CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NC_004350	Streptococcus mutans UA159, complete sequence	1 crisprs	DEDDh,cas3,csm6,csa3,DinG,csn2,cas2,cas1,cas9,WYL,cas4,cas7,cas5	0	5	5	0

Results visualization

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CRISPR-Cas detection and classification

Crispr_ID: NC_004350_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_004350_1

1327814-1328245

TypeII

II-A,II-B

Consensus_repeat	Method
GTTTTGGAACCATTCGAAACAACACAGCTCTAAAAC	CRT
GTTTTGGAACCATTCGAAACAACACAGCTCTAAAAC	PILER-CR
GTTTTGGAACCATTCGAAACAACACAGCTCTAAAAC	CRISPRCasFinder

6 spacers

csn2,cas2,cas1,cas9

The CRISPR arrays of NC_004350_1

>merge|NC_004350|1|1327814-1328245|CRT,PILER-CR,CRISPRCasFinder
ATTTTAGTAAATCAGTAACTAACATGGCTCTAAAACTCAAATGTAGTAGTTACTTTCTTTTCACATGTTTTGGAACCATTCGAAACAACACAGCTCTAAAACTGTGGCAAGTCATGTCCGAATACATAGGCAGTTTTGGAACCATTCGAAACAACACAGCTCTAAAACGTTTGTCTATTGTCTAATTGAAAATATTTAGTTTTGGAACCATTCGAAACAACACAGCTCTAAAACCTAACTATGATGACACAACAGCTTTTAGCGGTTTTGGAACCATTCGAAACAACACAGCTCTAAAACAGAGCACTAACTGCGCTAGCTGGTTCAATCGTTTTGGAACCATTCGAAACAACACAGCTCTAAAACTCACCATATTAATTAATGGCGTTTCCTTTTGTTTTGGAACCATTCGAAACAACACAGCTCTAAAAC

>NC_004350|1|1|1327814-1328245|CRT
ATTTTAGTAAATCAGTAACTAACATGGCTCTAAAAC	TCAAATGTAGTAGTTACTTTCTTTTCACAT
GTTTTGGAACCATTCGAAACAACACAGCTCTAAAAC	TGTGGCAAGTCATGTCCGAATACATAGGCA
GTTTTGGAACCATTCGAAACAACACAGCTCTAAAAC	GTTTGTCTATTGTCTAATTGAAAATATTTA
GTTTTGGAACCATTCGAAACAACACAGCTCTAAAAC	CTAACTATGATGACACAACAGCTTTTAGCG
GTTTTGGAACCATTCGAAACAACACAGCTCTAAAAC	AGAGCACTAACTGCGCTAGCTGGTTCAATC
GTTTTGGAACCATTCGAAACAACACAGCTCTAAAAC	TCACCATATTAATTAATGGCGTTTCCTTTT
GTTTTGGAACCATTCGAAACAACACAGCTCTAAAAC

>NC_004350|1|1|1327880-1328245|PILER-CR
GTTTTGGAACCATTCGAAACAACACAGCTCTAAAAC	TGTGGCAAGTCATGTCCGAATACATAGGCA
GTTTTGGAACCATTCGAAACAACACAGCTCTAAAAC	GTTTGTCTATTGTCTAATTGAAAATATTTA
GTTTTGGAACCATTCGAAACAACACAGCTCTAAAAC	CTAACTATGATGACACAACAGCTTTTAGCG
GTTTTGGAACCATTCGAAACAACACAGCTCTAAAAC	AGAGCACTAACTGCGCTAGCTGGTTCAATC
GTTTTGGAACCATTCGAAACAACACAGCTCTAAAAC	TCACCATATTAATTAATGGCGTTTCCTTTT
GTTTTGGAACCATTCGAAACAACACAGCTCTAAAAC

>NC_004350|1|1|1327880-1328245|CRISPRCasFinder
GTTTTGGAACCATTCGAAACAACACAGCTCTAAAAC	TGTGGCAAGTCATGTCCGAATACATAGGCA
GTTTTGGAACCATTCGAAACAACACAGCTCTAAAAC	GTTTGTCTATTGTCTAATTGAAAATATTTA
GTTTTGGAACCATTCGAAACAACACAGCTCTAAAAC	CTAACTATGATGACACAACAGCTTTTAGCG
GTTTTGGAACCATTCGAAACAACACAGCTCTAAAAC	AGAGCACTAACTGCGCTAGCTGGTTCAATC
GTTTTGGAACCATTCGAAACAACACAGCTCTAAAAC	TCACCATATTAATTAATGGCGTTTCCTTTT
GTTTTGGAACCATTCGAAACAACACAGCTCTAAAAC

Protein	Signature genes	Signature genes Name	Protein_function
NC_004350.2\|WP_002263550.1\|1335359_1336226_-\|NADPH-dependent-oxidoreductase	unknown	unknown	gnl\|CDD\|377026
NC_004350.2\|WP_002262721.1\|1326837_1327731_+\|LexA-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|119397
NC_004350.2\|WP_002262719.1\|1324323_1326075_-\|glucan-binding-protein	unknown	unknown	gnl\|CDD\|369832
NC_004350.2\|WP_002262712.1\|1316937_1318578_-\|phosphoenolpyruvate-carboxykinase-(ATP)	unknown	unknown	gnl\|CDD\|236471
NC_004350.2\|WP_002262716.1\|1320860_1321688_-\|alpha/beta-hydrolase	unknown	unknown	gnl\|CDD\|223669
NC_004350.2\|WP_002262717.1\|1321716_1323552_-\|elongation-factor-4	unknown	unknown	gnl\|CDD\|235462
NC_004350.2\|WP_002262710.1\|1314685_1315666_+\|Gfo/Idh/MocA-family-oxidoreductase	unknown	unknown	gnl\|CDD\|223745
NC_004350.2\|WP_002262713.1\|1318896_1319553_+\|Pr6Pr-family-membrane-protein	unknown	unknown	unknown
NC_004350.2\|WP_002263546.1\|1329082_1329745_-\|type-II-A-CRISPR-associated-protein-Csn2	csn2	cd09758_csn2_CAS-II-A	gnl\|CDD\|213408
NC_004350.2\|WP_002263547.1\|1329734_1330079_-\|CRISPR-associated-endonuclease-Cas2	cas2	COG3512_cas2_CAS-II-A:CAS-II-B:CAS-II-C	gnl\|CDD\|226043
NC_004350.2\|WP_002262714.1\|1319617_1320226_-\|hypothetical-protein	unknown	unknown	unknown
NC_004350.2\|WP_002263549.1\|1330941_1334979_-\|type-II-CRISPR-RNA-guided-endonuclease-Cas9	cas9	COG3513_cas9_CAS-II-A:CAS-II-B:CAS-II-C	gnl\|CDD\|226044
NC_004350.2\|WP_002262711.1\|1315662_1316745_+\|DEAD/DEAH-box-helicase	unknown	unknown	gnl\|CDD\|223587
NC_004350.2\|WP_002262715.1\|1320305_1320782_-\|GNAT-family-N-acetyltransferase	unknown	unknown	gnl\|CDD\|366181
NC_004350.2\|WP_002263544.1\|1328399_1328777_-\|type-II-toxin-antitoxin-system-HicB-family-antitoxin	unknown	unknown	gnl\|CDD\|374224
NC_004350.2\|WP_002352327.1\|1338775_1340209_+\|FAD-dependent-oxidoreductase	unknown	unknown	gnl\|CDD\|180854
NC_004350.2\|WP_002280228.1\|1337784_1338651_-\|helix-turn-helix-transcriptional-regulator	unknown	unknown	gnl\|CDD\|197666
NC_004350.2\|WP_002352326.1\|1330075_1330942_-\|type-II-CRISPR-associated-endonuclease-Cas1	cas1	cd09720_cas1_CAS-II-A:CAS-II-B:CAS-II-C	gnl\|CDD\|187851
NC_004350.2\|WP_086956939.1\|1336341_1337690_-\|IS3-like-element-ISSmu1-family-transposase	unknown	unknown	gnl\|CDD\|222853
NC_004350.2\|WP_002263545.1\|1328794_1328986_-\|type-II-toxin-antitoxin-system-HicA-family-toxin	unknown	unknown	gnl\|CDD\|377942

Protein	Function_ID	Function_description	E-value
NC_004350.2\|WP_002262721.1\|1326837_1327731_+\|LexA-family-transcriptional-regulator	gnl\|CDD\|119397	cd06529, S24_LexA-like, Peptidase S24 LexA-like proteins are involved in the SOS response leading to the repair of single-stranded DNA within the bacterial cell. This family includes: the lambda repressor CI/C2 family and related bacterial prophage repressor proteins; LexA (EC 3.4.21.88), the repressor of genes in the cellular SOS response to DNA damage; MucA and the related UmuD proteins, which are lesion-bypass DNA polymerases, induced in response to mitogenic DNA damage; RulA, a component of the rulAB locus that confers resistance to UV, and RuvA, which is a component of the RuvABC resolvasome that catalyzes the resolution of Holliday junctions that arise during genetic recombination and DNA repair. The LexA-like proteins contain two-domains: an N-terminal DNA binding domain and a C-terminal domain (CTD) that provides LexA dimerization as well as cleavage activity. They undergo autolysis, cleaving at an Ala-Gly or a Cys-Gly bond, separating the DNA-binding domain from the rest of the protein. In the presence of single-stranded DNA, the LexA, UmuD and MucA proteins interact with RecA, activating self cleavage, thus either derepressing transcription in the case of LexA or activating the lesion-bypass polymerase in the case of UmuD and MucA. The LexA proteins are serine proteases that carry out catalysis using a serine/lysine dyad instead of the prototypical serine/histidine/aspartic acid triad found in most serine proteases. LexA sequence homologs are found in almost all of the bacterial genomes sequenced to date, covering a large number of phyla, suggesting both, an ancient origin and a widespread distribution of lexA and the SOS response.	4.87065e-23
NC_004350.2\|WP_002262719.1\|1324323_1326075_-\|glucan-binding-protein	gnl\|CDD\|369832	pfam08363, GbpC, Glucan-binding protein C. This domain is found in the Streptococcus Glucan-binding protein C (GbpC) and also in surface protein antigen (Spa)-family proteins which show sequence similarity to GbpC.	2.89456e-110
NC_004350.2\|WP_002262712.1\|1316937_1318578_-\|phosphoenolpyruvate-carboxykinase-(ATP)	gnl\|CDD\|236471	PRK09344, PRK09344, phosphoenolpyruvate carboxykinase.	3.37821e-12
NC_004350.2\|WP_002262716.1\|1320860_1321688_-\|alpha/beta-hydrolase	gnl\|CDD\|223669	COG0596, MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [General function prediction only].	1.95778e-06
NC_004350.2\|WP_002262717.1\|1321716_1323552_-\|elongation-factor-4	gnl\|CDD\|235462	PRK05433, PRK05433, GTP-binding protein LepA; Provisional.	0
NC_004350.2\|WP_002262710.1\|1314685_1315666_+\|Gfo/Idh/MocA-family-oxidoreductase	gnl\|CDD\|223745	COG0673, MviM, Predicted dehydrogenases and related proteins [General function prediction only].	3.80539e-46
NC_004350.2\|WP_002263546.1\|1329082_1329745_-\|type-II-A-CRISPR-associated-protein-Csn2	gnl\|CDD\|213408	cd09758, Csn2, CRISPR/Cas system-associated protein Csn2. Csn2 is a Nmeni subtype-specific Cas protein, which may function in the adaptation process which mediates the incorporation of foreign nucleic acids into the microbial host genome. Csn 2 may interact directly with double-stranded DNA. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA. Csn2 has been predicted to be a functional analog of Cas4 based on anti-correlated phyletic patterns; also known as SPy1049 family.	3.55029e-116
NC_004350.2\|WP_002263547.1\|1329734_1330079_-\|CRISPR-associated-endonuclease-Cas2	gnl\|CDD\|226043	COG3512, COG3512, CRISPR-associated protein, Cas2 homolog [Defense mechanisms].	1.02077e-50
NC_004350.2\|WP_002263550.1\|1335359_1336226_-\|NADPH-dependent-oxidoreductase	gnl\|CDD\|377026	pfam03358, FMN_red, NADPH-dependent FMN reductase.	2.74106e-38
NC_004350.2\|WP_002263549.1\|1330941_1334979_-\|type-II-CRISPR-RNA-guided-endonuclease-Cas9	gnl\|CDD\|226044	COG3513, COG3513, Predicted CRISPR-associated nuclease, contains McrA/HNH-nuclease and RuvC-like nuclease domain [Defense mechanisms].	0
NC_004350.2\|WP_002262711.1\|1315662_1316745_+\|DEAD/DEAH-box-helicase	gnl\|CDD\|223587	COG0513, SrmB, Superfamily II DNA and RNA helicases [DNA replication, recombination, and repair / Transcription / Translation, ribosomal structure and biogenesis].	5.1744e-94
NC_004350.2\|WP_002262715.1\|1320305_1320782_-\|GNAT-family-N-acetyltransferase	gnl\|CDD\|366181	pfam00583, Acetyltransf_1, Acetyltransferase (GNAT) family. This family contains proteins with N-acetyltransferase functions such as Elp3-related proteins.	2.76682e-16
NC_004350.2\|WP_002263544.1\|1328399_1328777_-\|type-II-toxin-antitoxin-system-HicB-family-antitoxin	gnl\|CDD\|374224	pfam15919, HicB_lk_antitox, HicB_like antitoxin of bacterial toxin-antitoxin system. This is a family of HicB-like antitoxins.	4.28207e-15
NC_004350.2\|WP_002352327.1\|1338775_1340209_+\|FAD-dependent-oxidoreductase	gnl\|CDD\|180854	PRK07121, PRK07121, FAD-binding protein.	3.86242e-40
NC_004350.2\|WP_002280228.1\|1337784_1338651_-\|helix-turn-helix-transcriptional-regulator	gnl\|CDD\|197666	smart00342, HTH_ARAC, helix_turn_helix, arabinose operon control protein.	5.57862e-21
NC_004350.2\|WP_002352326.1\|1330075_1330942_-\|type-II-CRISPR-associated-endonuclease-Cas1	gnl\|CDD\|187851	cd09720, Cas1_II, CRISPR/Cas system-associated protein Cas1. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas1 is the most universal CRISPR system protein thought to be involved in spacer intergration. Cas1 is metal-dependent deoxyribonuclease, also binds RNA; Shown to possess a unique fold consisting of a N-terminal beta-strand domain and a C-terminal alpha-helical domain.	1.89519e-129
NC_004350.2\|WP_086956939.1\|1336341_1337690_-\|IS3-like-element-ISSmu1-family-transposase	gnl\|CDD\|222853	PHA02517, PHA02517, putative transposase OrfB; Reviewed.	1.04276e-48
NC_004350.2\|WP_002263545.1\|1328794_1328986_-\|type-II-toxin-antitoxin-system-HicA-family-toxin	gnl\|CDD\|377942	pfam07927, HicA_toxin, HicA toxin of bacterial toxin-antitoxin,. HicA_toxin is a bacterial family of toxins that act as mRNA interferases. The antitoxin that neutralizes this is family HicB, pfam15919.	7.41502e-15

>NC_004350.2|WP_002262721.1|1326837_1327731_+|LexA-family-transcriptional-regulator
MGRGKLTPQDLEAMKAISANLQRLLAESGMKQSHLATILNIPTSSLNEYVKGKSLPKIGNIQKIADYFGLQKSDIDPRFASKKDSSTLDKINHIAKQLEMKRQIKVLDFCYQQSKEQDETASLSASDETTEDKVADKSNHTQYQKVVDSFIAKELNDQTIIHWDNVIKAKDLYQTFGRQYENIQIYGEVSAGTGIWVGHEKQETIKYPIPIPEHDIALIVNGNSMEPLFYNGDVIFVKKTKAIHHGQIIVVIVNNEAYVKKLYRKNKEIRLISLNPDYDDIILKEDDTIEVIGTVIT
>NC_004350.2|WP_002262719.1|1324323_1326075_-|glucan-binding-protein
MKSKTAKITLLSSLALAAFGATNVFADEASTQLNSDTVAAPTADTQASEPAATEKEQSPVVAVVESHTQGNTTTTTSQVTSKELEDAKANANQEGLEVTETEAQKQPSVEAADADNKAQAQTINTAVADYQKAKAEFPQKQEQYNKDFEKYQSDVKEYEAQKAAYEQYKKEVAQGLASGRVEKAQGLVFINEPEAKLSIEGVNQYLTKEARQKHATEDILQQYNTDNYTASDFTQANPYDPKEDTWFKMKVGDQISVTYDNIVNSKYNDKKISKVKINYTLNSSTNNEGSALVNLFHDPTKTIFIGAQTSNAGRNDKISVTMQIIFYDENGNEIDLSGNNAIMSLSSLNHWTTKYGDHVEKVNLGDNEFVKIPGSSVDLHGNEIYSAKDNQYKANGATFNGDGADGWDAVNADGTPRAATAYYGAGAMTYKGEPFTFTVGGNDQNLPTTIWFATNSAVAVPKDPGAKPTPPEKPELKKPTVTWHKNLVVETKTEEVPPVTPPTTPDEPTPEKPKTPEDPQSPVVAKSVSFRTARKGEMRVRERDYQPTLPHAGAAKQNGLATLGAISTAFAAATLIAARKKEN
>NC_004350.2|WP_002262717.1|1321716_1323552_-|elongation-factor-4
MTIEQLKNRQEKIRNFSIIAHIDHGKSTLADRILEQTETVSSREMQAQLLDSMDLERERGITIKLNAIELNYKAKNGETYIFHLIDTPGHVDFTYEVSRSLAACEGAILVVDAAQGIEAQTLANVYLALDNDLEILPVINKIDLPAADPERVRTEIEDVIGLDASEAVLASAKAGIGIEEILEQIVEKVPAPKGDVEAPLKALIFDSVYDAYRGVILQIRVMDGMVKPGDKIELMSNGKTFDVTEVGIFTPKAVNRDFLATGDVGYLAASIKTVADTRVGDTVTLADCPAEAPLHGYKQLNPMVFAGIYPIDSSKYNDMREALEKLQLNDASLHFEPETSQALGFGFRCGFLGLLHMDVIQERLEREFNIDLIMTAPSVVYHVYTTDGERLEVSNPSEFPDPTKVDSIEEPYVKAQIMVPQEYVGAVMELSQRKRGDFVTMDYIDNNRVNVIYQIPLAEIVFDFFDKLKSSTRGYASFDYDISEYRKSKLVKMDILLNGDKVDALSFIVHKEFAYERGKLIVEKLKKIIPRQQFEVPIQAAIGQKIVARSDIKALRKNVLAKCYGGDVSRKRKLLEKQKAGKKRMKSIGSVEVPQEAFLSVLSMDDDDKKK
>NC_004350.2|WP_002262716.1|1320860_1321688_-|alpha/beta-hydrolase
MAALNKEMVNTLLGPIYTCHREGNPCFVFLSGAGFFSTADNFANIIDKLPDSIGILTIDAPNSGYSPVSNQANVGLRDWVNAILMIFEHFKFQSYLLCVHSIGGFAALQIMNQSSKACLGFIGLEPTTVMIYRAGFSSDLYPQLALRRQKLKTAADRLNYLKDLSRSHFSSQQFKQLWRGYDYCQRQLNDVQSLPDFKIRLALGEEDFKTGISEKIPSIVFSESFREKEYLESEYLNKHTQTKLILCGQHHYLHWSETNSILEKVEQLLSNHEKL
>NC_004350.2|WP_002262715.1|1320305_1320782_-|GNAT-family-N-acetyltransferase
MSIRLAQVTDIPVLKELLNQIFQVHQTVRPDLFKNTDKGSKYSETELKELLQDESKPIFVYTDGKNRVLGHLFLVIKETKGSSVSKPLKTLFIDDLCVSKEARGQKIGQELFEFALKYAKKLGCYDLTLNVWNDNKGALAFYERQGLKARETKMEKIL
>NC_004350.2|WP_002262714.1|1319617_1320226_-|hypothetical-protein
MPRRRASRRKSKKKAVFSILLTGITLIIIGLAVYFISAYFTNTKKTANKEKTQTHIVNPKKDPEEKKEADSASKATSKFDLTTIATGDYSSAAGTWQNELGDQLKFNASGLESATIQNATDFTISSGQATNDGLYQATLTSADSTVVYNLLFVKGGTAIPENYFTTGYSDTSDTSRDRLYISSQTTFGSDDFSKGIFYKSEN
>NC_004350.2|WP_002262713.1|1318896_1319553_+|Pr6Pr-family-membrane-protein
MSKTQAFRSLIALLGLIGVSIQIKQSGWGMLLYYTTLSNVIVCSFLTYLVIKEKRNGSINSNPKLLRLKGGVTMTIMITFMVYHFLLAPKVRSYDYYTIRNFLVHYIVPLSTIFDTLICDRRKIYRWFDPIIWTCLPLLYFGFALINGLLLKWPIPGTADSPFPYFFINMNKYGAQQVLINALVIALLYLLFGYILLGIKQMIGQKRQVTDNSSLNMS
>NC_004350.2|WP_002262712.1|1316937_1318578_-|phosphoenolpyruvate-carboxykinase-(ATP)
MVTRQHFSEDSMRKNNSYFSALKATIETAFYENHVVPLKELAEAYRLAAKSPNTIVLDTPVAHAEDLGLPKDAKILLENSGGIVGRTAKARRIFGQDSKEDAKILQIIREAIFQARHRTFYRADAVVGLDEAFMLRAHLMVPQDDINNLYSWLNNFQVLNDTYRERLKKSKRYEETDIYIFSDPEWSHPDYPDGLVYFDTNHNCAAILGLHYFGELKKATLTLAWGTANRNKYVACHGGLKIFEKEGQKPYVASFFGLSGSGKSTLTHAKHNGKYRIDVLHDDAFVISEEDGSTIALEPAYFDKTNDYPAGHREQKYFVAVQNCGAALDKEGHLRLVTEDIRNGNGRTIKSRFSTPNRVDRINHPIQSIFWIMKDDSLPPLIRVTDPIMASIMGCTLVTTRSTAENTTDSLDALIIEPYANPFRVYPLVEDYIKFQHLFESGVNCYIINTGSYLGQDIPKETTLDVIEQVVDGTAKFEPFGSVKGFEYLSSSHYKIPNFDKAYVKIIRQRMKIRLQYLEAFNRKNPKLSLPDEAISHLKDVLANLG
>NC_004350.2|WP_002262711.1|1315662_1316745_+|DEAD/DEAH-box-helicase
MKTQFPSVWQDKLSQKHFSAFTTIQEAAFDPIKNGKSLLGISPTGSGKTLAYLWPSLLTLTPKKAQQLLILAPNTELAGQIFEVAKEWAQPLNLTAQLFLSGSSQKRQIERLKKGPEIIIGTPGRVFDLVKLKKIKMMNVNTIVLDEFDDLLGKSQIHFVKNIVKRVPRDHQMIYMSATNSIDRTFLADDTLEIDLSKQTVDTISHYYITVAKRERGELLRKFSNIPNFRGLVFFNRLSDLGANEERLQFSGASAVSLASDVNIKFRKVILEKFKNHELSLLLATDLVARGIDIELLETVINFDLPRDKDAYNHRAGRTGRMGKNGIVVTFISHPEELKKLKKFAHVSEVYLKNQILHKK
>NC_004350.2|WP_002262710.1|1314685_1315666_+|Gfo/Idh/MocA-family-oxidoreductase
MLKLGIIGTGSISHQFIEAAQLSQHYQLTAVYSRKLETAEAFSARYQNIACYDMLDDFFNDAFDVLYIASPNALHFEHAKLALEAGKHIIVEKPAFSTPEELSNIIHSAEKKQLFFFEAARNYHEESLLLIKEFLSHKTVIGADFSYAKYSSKMKDLLAGKLPNVFSDKFSGGALVDLGIYPIYAAIKLFGKPKSVNYTATQLENTIDLNGNGNLIYPDFHVSIRAGKNYNTLEYAEIYTSEGTLRLNHIQGISSAIFQKHDGSREKLALPDIEHLMLEEAKHFAEMMNNKNEVIYQTWLEDAKTASQILYQMRQSAGIVFEADKK
>NC_004350.2|WP_002263544.1|1328399_1328777_-|type-II-toxin-antitoxin-system-HicB-family-antitoxin
MLKSYPVIFHKEEEGYWVEFPEFGGGTQGEDLEEAMKNARQMLESVLASYLDEGLVLPISSDIQKISVEDGFATMIQADPSPYLKNNKAIRKNVTVPEWLIRLADRDRVNYSEVLTKALEKKLQL
>NC_004350.2|WP_002263545.1|1328794_1328986_-|type-II-toxin-antitoxin-system-HicA-family-toxin
MPLTGKELAKLAINNGWEEVRVRGSHHHFKKDGVSYIVTIPIHGNKVLKIGLEKKLLRDLNLL
>NC_004350.2|WP_002263546.1|1329082_1329745_-|type-II-A-CRISPR-associated-protein-Csn2
MKLNFPILDEPITLEKSTILVLEDVQVFAQMVRNLYQYDEDSELKFFNRKFKSLKPSELMLVTDILGYDVNAPSLLKLVHADLENQFNEKPEVKSMVEKLANTITELIAYECLENELDLEYDEITILELIKALGVKIETQSDTIFEKMFEVLQVYKYLNKKKLLVFINTLSYFKREEIAQILEYIHLSDMVVLFLEPRKIDGFAQYILDEDYFLITESNN
>NC_004350.2|WP_002263547.1|1329734_1330079_-|CRISPR-associated-endonuclease-Cas2
MSYRYMRMILMFDMPTDTAEERKAYRKFRKFLLSEGFIMHQFSVYSKLLLNNSANTAMIARLKENNPKKGNITLLTVTEKQFARMIYLNGERDTSIANSDSRLVFLGEAFPDET
>NC_004350.2|WP_002352326.1|1330075_1330942_-|type-II-CRISPR-associated-endonuclease-Cas1
MGWRTVVVNTHSKLSYKNNHLIFKDAYQTEMIHLSEIDILLLETTDIVLSTMLIKRLVDENILVIFCDDKRLPTAMLMPYYARHDSSLQLSHQISWTEEVKCDVWTTIIAQKILNQSCYLGECFYFEKSQSIMDLYHDLEPFDPSNREGHSARIYFNTLFGNVFSREQDNDINAGLDYGYTLLLSMFAREVVVSGCMTQFGLKHANQFNQFNFASDIMEPFRPIVDRIVYENRNNSFIKIKRELFSMFSDTYLYNNKEMYLTNIVSDYTKKVIKALNNDGKGVPEFRI
>NC_004350.2|WP_002263549.1|1330941_1334979_-|type-II-CRISPR-RNA-guided-endonuclease-Cas9
MKKPYSIGLDIGTNSVGWAVVTDDYKVPAKKMKVLGNTDKSHIEKNLLGALLFDSGNTAEDRRLKRTARRRYTRRRNRILYLQEIFSEEMGKVDDSFFHRLEDSFLVTEDKRGERHPIFGNLEEEVKYHENFPTIYHLRQYLADNPEKVDLRLVYLALAHIIKFRGHFLIEGKFDTRNNDVQRLFQEFLAVYDNTFENSSLQEQNVQVEEILTDKISKSAKKDRVLKLFPNEKSNGRFAEFLKLIVGNQADFKKHFELEEKAPLQFSKDTYEEELEVLLAQIGDNYAELFLSAKKLYDSILLSGILTVTDVGTKAPLSASMIQRYNEHQMDLAQLKQFIRQKLSDKYNEVFSDVSKDGYAGYIDGKTNQEAFYKYLKGLLNKIEGSGYFLDKIEREDFLRKQRTFDNGSIPHQIHLQEMRAIIRRQAEFYPFLADNQDRIEKLLTFRIPYYVGPLARGKSDFAWLSRKSADKITPWNFDEIVDKESSAEAFINRMTNYDLYLPNQKVLPKHSLLYEKFTVYNELTKVKYKTEQGKTAFFDANMKQEIFDGVFKVYRKVTKDKLMDFLEKEFDEFRIVDLTGLDKENKVFNASYGTYHDLCKILDKDFLDNSKNEKILEDIVLTLTLFEDREMIRKRLENYSDLLTKEQVKKLERRHYTGWGRLSAELIHGIRNKESRKTILDYLIDDGNSNRNFMQLINDDALSFKEEIAKAQVIGETDNLNQVVSDIAGSPAIKKGILQSLKIVDELVKIMGHQPENIVVEMARENQFTNQGRRNSQQRLKGLTDSIKEFGSQILKEHPVENSQLQNDRLFLYYLQNGRDMYTGEELDIDYLSQYDIDHIIPQAFIKDNSIDNRVLTSSKENRGKSDDVPSKDVVRKMKSYWSKLLSAKLITQRKFDNLTKAERGGLTDDDKAGFIKRQLVETRQITKHVARILDERFNTETDENNKKIRQVKIVTLKSNLVSNFRKEFELYKVREINDYHHAHDAYLNAVIGKALLGVYPQLEPEFVYGDYPHFHGHKENKATAKKFFYSNIMNFFKKDDVRTDKNGEIIWKKDEHISNIKKVLSYPQVNIVKKVEEQTGGFSKESILPKGNSDKLIPRKTKKFYWDTKKYGGFDSPIVAYSILVIADIEKGKSKKLKTVKALVGVTIMEKMTFERDPVAFLERKGYRNVQEENIIKLPKYSLFKLENGRKRLLASARELQKGNEIVLPNHLGTLLYHAKNIHKVDEPKHLDYVDKHKDEFKELLDVVSNFSKKYTLAEGNLEKIKELYAQNNGEDLKELASSFINLLTFTAIGAPATFKFFDKNIDRKRYTSTTEILNATLIHQSITGLYETRIDLNKLGGD
>NC_004350.2|WP_002263550.1|1335359_1336226_-|NADPH-dependent-oxidoreductase
MKLVAIVGSNASFSYNRLLLQFIKERFGQAFALEILEIKELPLFNQDSSAADCPLIQKLNEDILNADGIIIATAEHNQTITASLKSMLEWLSYQLHPFKNKPVMIVGASYYNQGTSHAQEHLRQILNAPGLDAWVMPGNEFFLGNASEVFDENNQIKDDDTVIYLAQCLQRFIRYVTVVQELKGDSIQLSDAISGASESVQEDSAASAMLEKRLSLQKKETNTPFERALDKTYGPALKDTLEDPFDKDLDAQYKAIKKQPIPFEKALDNIFGKDLGIETTDPLDNLLR
>NC_004350.2|WP_086956939.1|1336341_1337690_-|IS3-like-element-ISSmu1-family-transposase
MKLTYEDKVLIYELKNQGYSLEQLSNKFGIKISNLSYMIKLIDHYGIEIVKKGKNRYYSPELKQEIIDKVLLEGRSQIRVSLDYALPSHGMLPNWIAQYKKNRYTIVEKTRGRPPKMGRKPKKKSEEMTELEQLQKELEYLRAENAVPKKVERTPIEGRKRARRKTEIVRGLVTEFSLDILLKIIKLARSTYYYHLKQLDKSNKDHAIKAEIQAIFTEHKGNYGYRRMTLELRNRGFLVNHKKVQRLMKVLGLEARIRRKRKYSSYQGEVGKKADNLIQRQFEASKPMEKCYTDVTEFAIPASGQKLYLSPVLDGFNSEIIAYNLSTSPNLIQVKAMLEQAFTEKHYTNTILHSDQGWQYQHDFYHQFLENKGIQPSMSRKGNSPDNGMMESFFGILKSEMFYGYEKTFKSLKQLEQAIVDYIDYYNNKRIKVKLKGLSPVQYRTKSFT
>NC_004350.2|WP_002280228.1|1337784_1338651_-|helix-turn-helix-transcriptional-regulator
MVRFISNTLSQTLNEPFQQSHKSCKHLYILEILSQVVIVSDQKQVPLQPYDIILAQSFNHLQIDSLDRNPILLRLYSLDFDLPSPLNQYTVGDNPLIHDLMNDHTSEDAYILFTNLSDLICHAYLDALEKLENLRDNNDEQVYIDFQRQKLAGLLFTELLRQHDAKVSKFASRFPSVNVKYASKDSQSGAIMKYVSDNVHHISLKEAAAHFFYQANYFSRLCHELFGISFNQLKTTIRLEIAKEQLRLTTKSVEEISQELGYKAVSNFHRNFKSQTGMTPNDYRQDKQ
>NC_004350.2|WP_002352327.1|1338775_1340209_+|FAD-dependent-oxidoreductase
MEKEYKVDVVVAGAGGAGLAAAHAAAQNGLKVLVLEKLKQIGGNTRISSGFFAINTKEQNAAGLKLSTQEAIRQLQEHNHFLSNGALLKNIIEHAKETLEEIEKLGMEIKLNPTKNSTQFAHFGNDYQGGSYHMYMNKDSSYLQIQKSLEAMGVTFIFGVRMTELLQDSNGHVRGLKALNDAGESMTVHAKASIITTGGFGGDKRRVAKVMRTLNLRTLGVPNMGEGLSAMEAAGGVNIDGSALIHAAQMAQSTVTQETKGKQLAGFNDSPLTQLLLSPLLWVDPNGSRFTNEDVVYDTVQWANAAYGVGSKYYYVMDTATLESYTKQPLLTISKSGPGASQAKGDFVSLAEQAVQQGIAFKGDSLEELAQNSGMDPIAFKATVAEYNKAIASQNDEIFSKSASSLKYDVKKGPFYAFIAQVIYLGTVGGVRVDKDLRVLDAYMKAIPGLYTGGANAGGYYAPRNYPAYEGLASGFS

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Click the colored protein region to show detailed information

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NC_004350_1	1.4\|1328048\|30\|NC_004350\|CRT,PILER-CR,CRISPRCasFinder	1328048-1328077	30	AM749121	Streptococcus phage M102 complete genome	13449-13478	0	1.0
NC_004350_1	1.4\|1328048\|30\|NC_004350\|CRT,PILER-CR,CRISPRCasFinder	1328048-1328077	30	NC_012884	Streptococcus phage M102, complete genome	13449-13478	0	1.0
NC_004350_1	1.4\|1328048\|30\|NC_004350\|CRT,PILER-CR,CRISPRCasFinder	1328048-1328077	30	MT430910	Streptococcus phage smHBZ8, complete genome	18614-18643	2	0.933
NC_004350_1	1.4\|1328048\|30\|NC_004350\|CRT,PILER-CR,CRISPRCasFinder	1328048-1328077	30	NC_029030	Streptococcus phage APCM01, complete genome	13540-13569	2	0.933
NC_004350_1	1.5\|1328114\|30\|NC_004350\|CRT,PILER-CR,CRISPRCasFinder	1328114-1328143	30	MT430910	Streptococcus phage smHBZ8, complete genome	26942-26971	3	0.9
NC_004350_1	1.5\|1328114\|30\|NC_004350\|CRT,PILER-CR,CRISPRCasFinder	1328114-1328143	30	NC_029030	Streptococcus phage APCM01, complete genome	10585-10614	6	0.8
NC_004350_1	1.6\|1328180\|30\|NC_004350\|CRT,PILER-CR,CRISPRCasFinder	1328180-1328209	30	NZ_CP032183	Citrobacter freundii strain AR_0116 plasmid unnamed5, complete sequence	27369-27398	6	0.8
NC_004350_1	1.1\|1327850\|30\|NC_004350\|CRT	1327850-1327879	30	NZ_CP047443	Spiroplasma citri strain BLH-MB plasmid pSciBLHMB-6, complete sequence	6199-6228	7	0.767
NC_004350_1	1.3\|1327982\|30\|NC_004350\|CRT,PILER-CR,CRISPRCasFinder	1327982-1328011	30	MT774388	CrAssphage cr112_1, complete genome	78406-78435	7	0.767
NC_004350_1	1.6\|1328180\|30\|NC_004350\|CRT,PILER-CR,CRISPRCasFinder	1328180-1328209	30	AP014198	Uncultured Mediterranean phage uvMED isolate uvMED-GF-C73-MedDCM-OCT-S33-C13, * SEQUENCING IN PROGRESS *	27674-27703	7	0.767
NC_004350_1	1.3\|1327982\|30\|NC_004350\|CRT,PILER-CR,CRISPRCasFinder	1327982-1328011	30	MN693413	Marine virus AFVG_25M209, complete genome	35417-35446	8	0.733
NC_004350_1	1.3\|1327982\|30\|NC_004350\|CRT,PILER-CR,CRISPRCasFinder	1327982-1328011	30	NZ_CP014203	Clostridium baratii strain CDC51267 plasmid pNPD11_1, complete sequence	112061-112090	8	0.733
NC_004350_1	1.4\|1328048\|30\|NC_004350\|CRT,PILER-CR,CRISPRCasFinder	1328048-1328077	30	MN694564	Marine virus AFVG_250M1179, complete genome	1766-1795	8	0.733
NC_004350_1	1.1\|1327850\|30\|NC_004350\|CRT	1327850-1327879	30	NZ_CP017108	Lactobacillus salivarius strain CICC23174 plasmid pLS_1 sequence	207932-207961	9	0.7

1. spacer 1.4|1328048|30|NC_004350|CRT,PILER-CR,CRISPRCasFinder matches to AM749121 (Streptococcus phage M102 complete genome) position: , mismatch: 0, identity: 1.0

ctaactatgatgacacaacagcttttagcg	CRISPR spacer
ctaactatgatgacacaacagcttttagcg	Protospacer
******************************

2. spacer 1.4|1328048|30|NC_004350|CRT,PILER-CR,CRISPRCasFinder matches to NC_012884 (Streptococcus phage M102, complete genome) position: , mismatch: 0, identity: 1.0

ctaactatgatgacacaacagcttttagcg	CRISPR spacer
ctaactatgatgacacaacagcttttagcg	Protospacer
******************************

3. spacer 1.4|1328048|30|NC_004350|CRT,PILER-CR,CRISPRCasFinder matches to MT430910 (Streptococcus phage smHBZ8, complete genome) position: , mismatch: 2, identity: 0.933

ctaactatgatgacacaacagcttttagcg	CRISPR spacer
ctaattatgatgacacaacagcgtttagcg	Protospacer
****.***************** *******

4. spacer 1.4|1328048|30|NC_004350|CRT,PILER-CR,CRISPRCasFinder matches to NC_029030 (Streptococcus phage APCM01, complete genome) position: , mismatch: 2, identity: 0.933

ctaactatgatgacacaacagcttttagcg	CRISPR spacer
ctaactatgacgacacgacagcttttagcg	Protospacer
**********.*****.*************

5. spacer 1.5|1328114|30|NC_004350|CRT,PILER-CR,CRISPRCasFinder matches to MT430910 (Streptococcus phage smHBZ8, complete genome) position: , mismatch: 3, identity: 0.9

agagcactaactgcgctagctggttcaatc	CRISPR spacer
agcgcactcactgcgctagctggttcaatt	Protospacer
** ***** ********************.

6. spacer 1.5|1328114|30|NC_004350|CRT,PILER-CR,CRISPRCasFinder matches to NC_029030 (Streptococcus phage APCM01, complete genome) position: , mismatch: 6, identity: 0.8

agagcactaactgcgctagctggttcaatc	CRISPR spacer
atagcactatctgcgctagatggttttaac	Protospacer
* ******* ********* *****. * *

7. spacer 1.6|1328180|30|NC_004350|CRT,PILER-CR,CRISPRCasFinder matches to NZ_CP032183 (Citrobacter freundii strain AR_0116 plasmid unnamed5, complete sequence) position: , mismatch: 6, identity: 0.8

tcaccatattaattaatggcgtttcctttt	CRISPR spacer
tccgcatatgaagtaatggcgtttcctgct	Protospacer
**  ***** ** ************** .*

8. spacer 1.1|1327850|30|NC_004350|CRT matches to NZ_CP047443 (Spiroplasma citri strain BLH-MB plasmid pSciBLHMB-6, complete sequence) position: , mismatch: 7, identity: 0.767

tcaaatgtagtagttactttcttttcacat	CRISPR spacer
ccaaatgtagtagttatattctttaaaaag	Protospacer
.***************. ******  * *

9. spacer 1.3|1327982|30|NC_004350|CRT,PILER-CR,CRISPRCasFinder matches to MT774388 (CrAssphage cr112_1, complete genome) position: , mismatch: 7, identity: 0.767

gtttgtctattgtctaattgaaaatattta	CRISPR spacer
tttaatctattgtgtaattggaaatattgt	Protospacer
 ** .******** ******.*******

10. spacer 1.6|1328180|30|NC_004350|CRT,PILER-CR,CRISPRCasFinder matches to AP014198 (Uncultured Mediterranean phage uvMED isolate uvMED-GF-C73-MedDCM-OCT-S33-C13, *** SEQUENCING IN PROGRESS ***) position: , mismatch: 7, identity: 0.767

tcaccatattaattaatggcgtttcctttt	CRISPR spacer
taaccatatttataaatggcgtttccggcg	Protospacer
* ******** ** ************  .

11. spacer 1.3|1327982|30|NC_004350|CRT,PILER-CR,CRISPRCasFinder matches to MN693413 (Marine virus AFVG_25M209, complete genome) position: , mismatch: 8, identity: 0.733

gtttgtctattgtctaattgaaaatattta	CRISPR spacer
ataattctattatctaattggaaatattct	Protospacer
.*   ******.********.*******.

12. spacer 1.3|1327982|30|NC_004350|CRT,PILER-CR,CRISPRCasFinder matches to NZ_CP014203 (Clostridium baratii strain CDC51267 plasmid pNPD11_1, complete sequence) position: , mismatch: 8, identity: 0.733

gtttgtctattgtctaattgaaaatattta	CRISPR spacer
tcctcattactttctaattgaaaatattta	Protospacer
 ..*  .**.* ******************

13. spacer 1.4|1328048|30|NC_004350|CRT,PILER-CR,CRISPRCasFinder matches to MN694564 (Marine virus AFVG_250M1179, complete genome) position: , mismatch: 8, identity: 0.733

ctaactatgatgacacaacagcttttagcg	CRISPR spacer
ggaattatgatgacacaacagctgacggtg	Protospacer
  **.******************  ..*.*

14. spacer 1.1|1327850|30|NC_004350|CRT matches to NZ_CP017108 (Lactobacillus salivarius strain CICC23174 plasmid pLS_1 sequence) position: , mismatch: 9, identity: 0.7

tcaaatgtagtagttactttcttttcacat	CRISPR spacer
gcttgagtagtaattactttcttttcagtc	Protospacer
 *  . ******.**************  .

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

871724 : 878574

Bacillus_phage(50.0%)

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_002263288.1\|871724_872213_-	NADPH-dependent 7-cyano-7-deazaguanine reductase QueF	E7DN65	Pneumococcus_phage	1.1e-45	57.2
WP_002263289.1\|872225_872942_-	7-carboxy-7-deazaguanine synthase QueE	E7DN68	Pneumococcus_phage	4.8e-63	48.4
WP_002263290.1\|872938_873385_-	6-carboxytetrahydropterin synthase QueD	J9PV91	Bacillus_phage	1.1e-41	60.6
WP_002263291.1\|873384_874038_-	7-cyano-7-deazaguanine synthase QueC	A0A2H4J8Q7	uncultured_Caudovirales_phage	7.7e-60	52.4
WP_002263292.1\|874589_875024_+	winged helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_002263293.1\|875027_876830_+	ABC transporter ATP-binding protein	W8CYL7	Bacillus_phage	2.2e-32	24.7
WP_002263294.1\|876819_878574_+	ABC transporter ATP-binding protein	W8CYL7	Bacillus_phage	7.9e-43	27.8

DBSCAN-SWA_2

1019801 : 1028585

Bacillus_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_002262263.1\|1019801_1021517_+	phospho-sugar mutase	A0A1X9I671	Streptococcus_phage	9.8e-272	82.5
WP_002262262.1\|1021647_1023393_-	ABC transporter ATP-binding protein	W8CYL7	Bacillus_phage	5.8e-54	29.0
WP_002352279.1\|1023389_1025123_-	ABC transporter ATP-binding protein	W8CYL7	Bacillus_phage	4.0e-39	25.8
WP_002262260.1\|1025132_1025747_-	lysozyme family protein	A0A223LKM8	Bacillus_phage	1.2e-22	37.6
WP_002262259.1\|1025748_1026726_-	nucleoid-associated protein	NA	NA	NA	NA
WP_002262258.1\|1026722_1027985_-	serine hydroxymethyltransferase	A0A219YB23	Aeromonas_phage	4.3e-99	52.3
WP_002262257.1\|1027994_1028585_-	threonylcarbamoyl-AMP synthase	A0A291ATS8	Pandoravirus	9.5e-17	33.7

DBSCAN-SWA_3

1569393 : 1583237

Streptococcus_phage(84.62%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_002262695.1\|1569393_1570221_+	exodeoxyribonuclease III	M1PSC0	Streptococcus_phage	2.1e-123	76.9
WP_002262694.1\|1570285_1570909_-	endonuclease III	NA	NA	NA	NA
WP_002262693.1\|1570973_1571327_-	arsenate reductase family protein	M1PLC0	Streptococcus_phage	4.8e-40	67.0
WP_002262692.1\|1571363_1571858_-	methylated-DNA--[protein]-cysteine S-methyltransferase	M1PFU9	Streptococcus_phage	9.7e-47	56.1
WP_002262691.1\|1571946_1573128_-	D-3-phosphoglycerate dehydrogenase	M1NSB9	Streptococcus_phage	7.9e-180	79.6
WP_002262690.1\|1573213_1573768_-	GNAT family N-acetyltransferase	M1PSC3	Streptococcus_phage	1.6e-50	64.4
WP_002262689.1\|1573918_1574059_-	hypothetical protein	NA	NA	NA	NA
WP_002262688.1\|1574176_1575268_-	3-phosphoserine/phosphohydroxythreonine transaminase	M1Q1P2	Streptococcus_phage	1.2e-169	79.0
WP_002262687.1\|1575487_1575829_-	P-II family nitrogen regulator	NA	NA	NA	NA
WP_002262686.1\|1575844_1577080_-	ammonium transporter	NA	NA	NA	NA
WP_002263897.1\|1577384_1578251_-	16S rRNA (cytidine(1402)-2'-O)-methyltransferase	M1PLC5	Streptococcus_phage	3.8e-115	73.5
WP_002262684.1\|1578256_1578589_-	DNA replication initiation control protein YabA	M1PFV3	Streptococcus_phage	6.1e-29	58.2
WP_002262683.1\|1578581_1579388_-	signal peptidase II	NA	NA	NA	NA
WP_002262682.1\|1579384_1580260_-	DNA polymerase III subunit delta'	M1NSC1	Streptococcus_phage	7.6e-79	54.1
WP_002262681.1\|1580272_1580911_-	dTMP kinase	M1PSC7	Streptococcus_phage	3.4e-76	65.6
WP_002262680.1\|1580987_1581647_-	CBS domain-containing protein	M1NSC5	Streptococcus_phage	7.3e-66	59.7
WP_002262679.1\|1581762_1582473_-	ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	7.2e-19	28.9
WP_002262678.1\|1582472_1583237_-	ABC transporter ATP-binding protein	A0A2H4PQG7	Staphylococcus_phage	1.6e-16	26.4

DBSCAN-SWA_4

1779163 : 1789908

uncultured_Mediterranean_phage(50.0%)

transposase,bacteriocin,tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_002263348.1\|1779163_1780444_+\|tRNA	serine--tRNA ligase	A0A1B1IVT2	uncultured_Mediterranean_phage	8.8e-92	51.1
WP_002352361.1\|1781126_1781390_-\|bacteriocin	Blp family class II bacteriocin	NA	NA	NA	NA
WP_002263346.1\|1781693_1781879_-\|bacteriocin	ComC/BlpC family leader-containing pheromone/bacteriocin	NA	NA	NA	NA
WP_086956939.1\|1781998_1783347_-\|transposase	IS3-like element ISSmu1 family transposase	A0A1B1P773	Bacillus_phage	1.6e-64	51.5
WP_002263734.1\|1783455_1783617_-\|bacteriocin	ComC/BlpC family leader-containing pheromone/bacteriocin	NA	NA	NA	NA
WP_002263733.1\|1783661_1783916_-\|bacteriocin	Blp family class II bacteriocin	NA	NA	NA	NA
WP_002263739.1\|1786501_1787515_+	HlyD family efflux transporter periplasmic adaptor subunit	NA	NA	NA	NA
WP_002263740.1\|1787776_1787920_-	hypothetical protein	NA	NA	NA	NA
WP_002263742.1\|1788211_1789234_-	thiol reductase thioredoxin	NA	NA	NA	NA
WP_002263743.1\|1789719_1789908_-\|bacteriocin	Blp family class II bacteriocin	NA	NA	NA	NA

DBSCAN-SWA_5

2010534 : 2022135

Staphylococcus_phage(37.5%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_002262446.1\|2010534_2011140_-	transglycosylase SLT domain-containing protein	Q4Z8Z7	Staphylococcus_phage	5.5e-28	62.2
WP_002262447.1\|2011301_2012168_-	LysM peptidoglycan-binding domain-containing protein	A0A288TY55	Enterococcus_phage	1.3e-22	75.7
WP_002262448.1\|2012356_2013151_-	energy-coupling factor transporter transmembrane protein EcfT	NA	NA	NA	NA
WP_002262449.1\|2013143_2013986_-	energy-coupling factor transporter ATPase	A0A2H4PQG7	Staphylococcus_phage	9.1e-13	26.6
WP_002262450.1\|2013961_2014804_-	energy-coupling factor transporter ATPase	A0A2H4PQG7	Staphylococcus_phage	4.7e-17	27.2
WP_002262451.1\|2014807_2015350_-	CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase	NA	NA	NA	NA
WP_002262452.1\|2015361_2016339_-	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_002352377.1\|2016411_2017704_-	insulinase family protein	A0A2H4UVM3	Bodo_saltans_virus	8.0e-08	26.3
WP_002262454.1\|2017705_2018953_-	insulinase family protein	A0A1X9I714	Streptococcus_phage	1.1e-99	45.7
WP_002262455.1\|2019031_2019397_+	S4 domain-containing protein YaaA	A0A1X9I5V8	Streptococcus_phage	3.1e-18	57.3
WP_002262456.1\|2019399_2020491_+	DNA replication/repair protein RecF	NA	NA	NA	NA
WP_002262457.1\|2020653_2022135_-	IMP dehydrogenase	A0A1V0SHK8	Klosneuvirus	2.6e-95	40.3

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage