CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NC_004572	Tropheryma whipplei str. Twist, complete sequence	2 crisprs	DEDDh	1	1	2	0

Results visualization

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CRISPR-Cas detection and classification

Crispr_ID: NC_004572_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_004572_1

267626-267710

Orphan

Consensus_repeat	Method
ACCCAATCCAAAAAATACCGGGACAGACAA	CRISPRCasFinder

1 spacers

The CRISPR arrays of NC_004572_1

>merge|NC_004572|1|267626-267710|CRISPRCasFinder
ACCCAATCCAAAAAATACCGGGACAGACAAATGCGATATACAACCCAAATAGTCAACCCAATCCAAAAAATACCGGGACAGACAA

>NC_004572|1|1|267626-267710|CRISPRCasFinder
ACCCAATCCAAAAAATACCGGGACAGACAA	ATGCGATATACAACCCAAATAGTCA
ACCCAATCCAAAAAATACCGGGACAGACAA

Protein	Signature genes	Signature genes Name	Protein_function
NC_004572.3\|WP_044143904.1\|255495_255918_+\|hypothetical-protein	unknown	unknown	unknown
NC_004572.3\|WP_044143907.1\|262517_263147_+\|putative-Ig-domain-containing-protein	unknown	unknown	unknown
NC_004572.3\|WP_166806551.1\|273068_276632_+\|putative-Ig-domain-containing-protein	unknown	unknown	gnl\|CDD\|310150
NC_004572.3\|WP_155105162.1\|263964_265107_-\|MFS-transporter	unknown	unknown	gnl\|CDD\|340883
NC_004572.3\|WP_080502112.1\|257319_257682_+\|putative-Ig-domain-containing-protein	unknown	unknown	gnl\|CDD\|310150
NC_004572.3\|WP_011102420.1\|259505_260726_+\|aspartate-carbamoyltransferase	unknown	unknown	gnl\|CDD\|183362
NC_004572.3\|WP_038103833.1\|285099_286803_+\|dihydroxy-acid-dehydratase	unknown	unknown	gnl\|CDD\|234861
NC_004572.3\|WP_011102426.1\|276628_277975_+\|16S-rRNA-(adenine(1518)-N(6)/adenine(1519)-N(6))--dimethyltransferase	unknown	unknown	gnl\|CDD\|234708
NC_004572.3\|WP_044143906.1\|258402_258684_+\|putative-Ig-domain-containing-protein	unknown	unknown	gnl\|CDD\|310150
NC_004572.3\|WP_080502113.1\|261821_262091_+\|putative-Ig-domain-containing-protein	unknown	unknown	unknown
NC_004572.3\|WP_080502114.1\|280118_280712_+\|putative-Ig-domain-containing-protein	unknown	unknown	gnl\|CDD\|310150
NC_004572.3\|WP_155105130.1\|272520_272892_+\|hypothetical-protein	unknown	unknown	unknown
NC_004572.3\|WP_011096512.1\|288585_288828_+\|acetolactate-synthase-small-subunit	unknown	unknown	gnl\|CDD\|153150
NC_004572.3\|WP_011102423.1\|269282_270194_+\|ABC-transporter-permease	unknown	unknown	gnl\|CDD\|225088
NC_004572.3\|WP_011102428.1\|286847_288593_+\|acetolactate-synthase-large-subunit	unknown	unknown	gnl\|CDD\|236098
NC_004572.3\|WP_155105132.1\|257756_257906_+\|hypothetical-protein	unknown	unknown	unknown
NC_004572.3\|WP_155105133.1\|259338_259509_+\|hypothetical-protein	unknown	unknown	unknown
NC_004572.3\|WP_080502098.1\|280656_281118_+\|putative-Ig-domain-containing-protein	unknown	unknown	gnl\|CDD\|310150
NC_004572.3\|WP_011096520.1\|265209_266340_+\|peptide-chain-release-factor-2	unknown	unknown	gnl\|CDD\|234799
NC_004572.3\|WP_011102424.1\|270205_270841_+\|SsrA-binding-protein-SmpB	unknown	unknown	gnl\|CDD\|376590

Protein	Function_ID	Function_description	E-value
NC_004572.3\|WP_011102428.1\|286847_288593_+\|acetolactate-synthase-large-subunit	gnl\|CDD\|236098	PRK07789, PRK07789, acetolactate synthase 1 catalytic subunit; Validated.	0
NC_004572.3\|WP_155105162.1\|263964_265107_-\|MFS-transporter	gnl\|CDD\|340883	cd17325, MFS_MdtG_SLC18_like, bacterial MdtG-like and eukaryotic solute carrier 18 (SLC18) family of the Major Facilitator Superfamily of transporters. This family is composed of eukaryotic solute carrier 18 (SLC18) family transporters and related bacterial multidrug resistance (MDR) transporters including several proteins from Escherichia coli such as multidrug resistance protein MdtG, from Bacillus subtilis such as multidrug resistance proteins 1 (Bmr1) and 2 (Bmr2), and from Staphylococcus aureus such as quinolone resistance protein NorA. The family also includes Escherichia coli arabinose efflux transporters YfcJ and YhhS. MDR transporters are drug/H+ antiporters (DHA) that mediate the efflux of a variety of drugs and toxic compounds, and confer resistance to these compounds. The SLC18 transporter family includes vesicular monoamine transporters (VAT1 and VAT2), vesicular acetylcholine transporter (VAChT), and SLC18B1, which is proposed to be a vesicular polyamine transporter (VPAT). The MdtG/SLC18 family belongs to the Major Facilitator Superfamily (MFS) of membrane transport proteins, which are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	1.30138e-28
NC_004572.3\|WP_080502112.1\|257319_257682_+\|putative-Ig-domain-containing-protein	gnl\|CDD\|310150	pfam05345, He_PIG, Putative Ig domain. This alignment represents the conserved core region of ~90 residue repeat found in several haemagglutinins and other cell surface proteins. Sequence similarities to (pfam02494) and (pfam00801) suggest an Ig-like fold (personal obs:C. Yeats). So this family may be similar in function to the (pfam02639) and (pfam02638) domains. This domain is also found in the WisP family of proteins of Tropheryma whipplei.	1.70963e-05
NC_004572.3\|WP_011102420.1\|259505_260726_+\|aspartate-carbamoyltransferase	gnl\|CDD\|183362	PRK11891, PRK11891, aspartate carbamoyltransferase; Provisional.	0
NC_004572.3\|WP_038103833.1\|285099_286803_+\|dihydroxy-acid-dehydratase	gnl\|CDD\|234861	PRK00911, PRK00911, dihydroxy-acid dehydratase; Provisional.	0
NC_004572.3\|WP_044143906.1\|258402_258684_+\|putative-Ig-domain-containing-protein	gnl\|CDD\|310150	pfam05345, He_PIG, Putative Ig domain. This alignment represents the conserved core region of ~90 residue repeat found in several haemagglutinins and other cell surface proteins. Sequence similarities to (pfam02494) and (pfam00801) suggest an Ig-like fold (personal obs:C. Yeats). So this family may be similar in function to the (pfam02639) and (pfam02638) domains. This domain is also found in the WisP family of proteins of Tropheryma whipplei.	0.00650683
NC_004572.3\|WP_080502114.1\|280118_280712_+\|putative-Ig-domain-containing-protein	gnl\|CDD\|310150	pfam05345, He_PIG, Putative Ig domain. This alignment represents the conserved core region of ~90 residue repeat found in several haemagglutinins and other cell surface proteins. Sequence similarities to (pfam02494) and (pfam00801) suggest an Ig-like fold (personal obs:C. Yeats). So this family may be similar in function to the (pfam02639) and (pfam02638) domains. This domain is also found in the WisP family of proteins of Tropheryma whipplei.	0.0004801
NC_004572.3\|WP_011096512.1\|288585_288828_+\|acetolactate-synthase-small-subunit	gnl\|CDD\|153150	cd04878, ACT_AHAS, N-terminal ACT domain of the Escherichia coli IlvH-like regulatory subunit of acetohydroxyacid synthase (AHAS). ACT_AHAS: N-terminal ACT domain of the Escherichia coli IlvH-like regulatory subunit of acetohydroxyacid synthase (AHAS). AHAS catalyses the first common step in the biosynthesis of the three branched-chain amino acids. The first step involves the condensation of either pyruvate or 2-ketobutyrate with the two-carbon hydroxyethyl fragment derived from another pyruvate molecule, covalently bound to the coenzyme thiamine diphosphate. Bacterial AHASs generally consist of regulatory and catalytic subunits. The effector (valine) binding sites are proposed to be located in two symmetrically related positions in the interface between a pair of N-terminal ACT domains with the C-terminal domain of IlvH contacting the catalytic dimer. Plants Arabidopsis and Oryza have tandem IlvH subunits; both the first and second ACT domain sequences are present in this CD. Members of this CD belong to the superfamily of ACT regulatory domains.	3.0742e-23
NC_004572.3\|WP_011102423.1\|269282_270194_+\|ABC-transporter-permease	gnl\|CDD\|225088	COG2177, FtsX, Cell division protein [Cell division and chromosome partitioning].	9.32764e-41
NC_004572.3\|WP_166806551.1\|273068_276632_+\|putative-Ig-domain-containing-protein	gnl\|CDD\|310150	pfam05345, He_PIG, Putative Ig domain. This alignment represents the conserved core region of ~90 residue repeat found in several haemagglutinins and other cell surface proteins. Sequence similarities to (pfam02494) and (pfam00801) suggest an Ig-like fold (personal obs:C. Yeats). So this family may be similar in function to the (pfam02639) and (pfam02638) domains. This domain is also found in the WisP family of proteins of Tropheryma whipplei.	3.77518e-05
NC_004572.3\|WP_080502098.1\|280656_281118_+\|putative-Ig-domain-containing-protein	gnl\|CDD\|310150	pfam05345, He_PIG, Putative Ig domain. This alignment represents the conserved core region of ~90 residue repeat found in several haemagglutinins and other cell surface proteins. Sequence similarities to (pfam02494) and (pfam00801) suggest an Ig-like fold (personal obs:C. Yeats). So this family may be similar in function to the (pfam02639) and (pfam02638) domains. This domain is also found in the WisP family of proteins of Tropheryma whipplei.	1.14067e-05
NC_004572.3\|WP_011102426.1\|276628_277975_+\|16S-rRNA-(adenine(1518)-N(6)/adenine(1519)-N(6))--dimethyltransferase	gnl\|CDD\|234708	PRK00274, ksgA, 16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase RsmA.	1.61415e-63
NC_004572.3\|WP_011096520.1\|265209_266340_+\|peptide-chain-release-factor-2	gnl\|CDD\|234799	PRK00578, prfB, peptide chain release factor 2; Validated.	0
NC_004572.3\|WP_011102424.1\|270205_270841_+\|SsrA-binding-protein-SmpB	gnl\|CDD\|376590	pfam01668, SmpB, SmpB protein.	2.00388e-67

>NC_004572.3|WP_011096520.1|265209_266340_+|peptide-chain-release-factor-2
MNITELFDSLKEIEKTFSEITSVVSPVLLSKRIAELTARVSDPDLWTTPDRAQQIARELSITKAQLDRLTNLEAQLDEMRVLVTLLENEHDAGLLDEGSRKAKLLLEEANHLLIQNMLNNEYDCYPAVLTIRAGAGGIDAADFAQMLLRMYIRWAQKHSSEAIVMDISYAEEAGIRSATLRIDLPFAFGKLHQESGTHRLVRISPFNAAGKRHTSFAAVEVIPLLEEVSSIEITNDEIRIDVFRSSGPGGQSVNTTDSAVRITHLPTGIVVSCQNEKSQIQNRESAMRILRARLLLNKRQEEAAIRKELAGNIVASWGEQVRNYVLAPYQLVKDLRSLHESSMPDKVFDGDIDGFIDAGIKWHAQKHILNQNGTRE
>NC_004572.3|WP_155105162.1|263964_265107_-|MFS-transporter
MVEGGLLPSVALIAAHESSSSALAGLAVSAGLIGYLASNIPGGIVVSRFGELRGMMIALSCAGISVLINIFSSSVALLTFGVFLSGFSFGAYGVARHSFMTLYTPLKVRARAFSVLGGAFRLGGALGTFLVSGVVVLTGNVRSVFVVHLAIVILLVIFLFLVRNVQKTDKSPKMLAEQPNSIKAMWEAVQSKKGQLITIGSAAGILAAARVSRSVILPLVGLHVGLKPEQITFIIGIGSTLEAFLFYSSGYVMDKWGRVWSAAPALFMVGGAYLLVFFAESYVAFLAISLLMGIGNALGSGIILTLGADLAGTSDQTAFISVWRLVTDIGQSVGPLGMSTLLGITSLTGAAGVMGLTCFAAAGIMIRYLHIYLPNKRAKT
>NC_004572.3|WP_044143907.1|262517_263147_+|putative-Ig-domain-containing-protein
MPLTHHIYTVVVTGTAPTVTNNATTLTSTIVSATYTFLVTSTTPGLSSTATGVSIGQTNITITPTTQGYITSYTVASTDATSGGTSANGLPKGLTLNSSGTITGSIDTSVTPGEYKVSFYAFASPVATLRIPSYLVTYTFYVLPSNSSSVHALTSPSRACNKQTYCGLIMQNIALDDASTSFTVKAIPNYYDYPSDFKNKLSHRVTSVM
>NC_004572.3|WP_080502113.1|261821_262091_+|putative-Ig-domain-containing-protein
MTPTTQGYITSYTVTNTDITSGGTNANGLPKGLTLDATKGTITGSIDGGVSTELYKVTITATAPSYSSSTTLTSTSVTATYTILITPVV
>NC_004572.3|WP_011102420.1|259505_260726_+|aspartate-carbamoyltransferase
MTAHNTPKVHCVIRQALRGQRIGPRQLAEQIGVDIKQLWSWLEPTWSQTLDIPQSILHDLEDAIDDTSAFYNTQHLLSIDQINRRSLERLFYVTDMFQPLARRQVRCNILNGAVLVCLFYEASTRTRFSFSTAFSRMGGAVVTEADMLQSSSVAKGESTSDTSRVISGYADIVVVRHSELGFAERYASDSLVPVINAGDGSGEHPTQAILDVYTIESEFLYREKTIDGSCIAIIGDLKHGRTVHSLIKLLSLYEGLTFKIFSITDLELPNDFHDLLSGRGHTLEVCDSLRNAVNAADVIYATRVQTERIAQDLTAVTGCRLTREVLDDCKKDVIVLHPLPRDSRPDALDIGTDLDSYSGFMPFGQANNGVPVRMAIFSEILGITDKIEFADSIPWARRIPYPQALP
>NC_004572.3|WP_155105133.1|259338_259509_+|hypothetical-protein
MQNIALDDASTSFTVKAIPNYYDYPSSFKSSFTHTVTLWNYKSTAKSQGRLIKLVM
>NC_004572.3|WP_044143906.1|258402_258684_+|putative-Ig-domain-containing-protein
MCCVTCNTTTYTNLSYTVTNTTETSPTGSGGLPKGLTLDTTKGEITGSIDTGVSQGIYTVVVTGTAPTVTSNATTLSSTTVSAVYTILVTHNP
>NC_004572.3|WP_155105132.1|257756_257906_+|hypothetical-protein
MTSTLPNGNTTVSSVTAAPLPNGKVTFTWPTDVLTEGGPEYSKQKNKYQ
>NC_004572.3|WP_080502112.1|257319_257682_+|putative-Ig-domain-containing-protein
MTPTTQGYITSYTVTNTGVTSGGTGANGLPKGLSIDTTKGTITGSIDTGVTPGEYVATITVTYSNASTSKTEVSPVLPSSSVHALTSPNRTAYPQVTCSHYSATGTRLCYVTCHLLPPAV
>NC_004572.3|WP_044143904.1|255495_255918_+|hypothetical-protein
MPSISGTEVNGKFSYPTDVLTKGGKDYSQQITTKPMTVIYTTGRGQSLPPGLTLNTSTARNASTSFPVKAIPNYYDYPGDFKSKLSHRVTLWNYTAAGNGVPSIHAVTSYLPNGSDTFLYPTNALTTGGSGYSSQENKYQ
>NC_004572.3|WP_011102423.1|269282_270194_+|ABC-transporter-permease
MFTFILSELIHNVRRSASMVSSVIIVTFISLTFVGTAALMQLQIVHMKSFWYDRAQVAIFLCTEHSSQSTCSAGKATEEQKDSVRQRLDSSVIKPLIEKYYFENHEQAYKNFKEQFKNNKIVELTTPDQLNETFWVKLHNPSQSTVIIEAFNDISGVDSVVDQRQYLNQIFYILNLASVTSISIAAVMLIAAVMLIATTIRLSAFTRRKEIEIMRLVGASNFFVQAPFVLEGIFAASIGALLSSIAIVSIAQFFITDYLAVKLPVVSFFSVGDSLIIVPIIFGIAILLSGLSAKFSISRSLRV
>NC_004572.3|WP_011102424.1|270205_270841_+|SsrA-binding-protein-SmpB
MHRRSSKSYSSRNSKIPERSKIPDCVIASNKSAEYNYFLDKTFEAGLVLLGSEVKSVRQQKISLSEAYIYEDNSEIWLANLYIPEHKTGGWTNHNPRRLRKLLLHKYQIARLRKDLLIPGITLVPIKFYFRNGRAKLLIALARGKKLIDKREVIKEREATLEANRALKHRLRRPRAQRNTQRSVTPRRTRENKNVRGSKARSARRNVRREN
>NC_004572.3|WP_155105130.1|272520_272892_+|hypothetical-protein
MSSIKDVTLPGGKYTVPSVNAVAVIVNGIYIYPTDVLTKGGEGYSQQVTPAPSHMQLRRNKRSTTQSLKYTNHPLFIPTNTIFIIQQSGSATISDSFPPILGATSITYSTQSLHIPNIYLTSP
>NC_004572.3|WP_166806551.1|273068_276632_+|putative-Ig-domain-containing-protein
MQNIALDDASTSFTVKAIPNYYDYPSDFKNKLSHRVTLWNYINAGNGVPSISGTEVNNKLTYPTDVLTKGGSGYSSQTTSVPMTVIYTMDTKKNPLPSGLTLITSTVPQYLFTYTRTTTQTYTSTYTSKSPSYSSYPVTITARLVYITKQPYIKAGEGKARHIAISEITAYRTFFTSYTHTIYSYANPSLKARVLLYTQSQSNVSITPILYGSFSISTYVLVDTTGATSGSTGLPKGLSIDTTKGEITGSIDGGVTPGEYKVSFYAFASPVATLRIPSYLVTYTFYVLPSNSSSVHALTSPSRTASVTFMSTTYTNLSYTVTNTTETSPTGSGGLPKGLTLDTTKGEITGSIDTGVTPGEYVAIITVTYSSNSKTEVSPSTVTYTHTFLVDQSTTPSLSNQATGVSIGQTNITITPKTTGYITSYTVASTDATSGGTSANGLPKGLTLNSSGTITGSIDTSVSQGIYTVVVTGTAPTVTNNATTLTSTIVSATYTFLVTSTTPGLSSTATGVSIGQTNITITPTTQGYITSYTVTNTTETSPTGSGGLPKGLTLDTTKGTITGSIDTGVTTGLYKVTITATAPSYSSSATTLTSTIVSAVYTICVYNSLGLAYLGYLVTQPYKDIYNYFKGSDDCGHTAPWVANAAAAGLLGLIGGLAALPTRKSTTKIPTTKKTTTKRTTRRTTQPPITIPKPTATTLTPRTTNRVRFTSRASQLQSNLPFRSNYLSPDLISPSISYTSQDLVVTVYKHASSVYMTQVLGPATYSLPNFVTYDTDPGVNRVPVYLFLNTTDGRLSGSVEANTGTYTFPVVVNGVYTVPYTVVVTELPSQDLVVTVYKHASSVYMTQVLGPATYSLPNFVTYDTDPGVNRVPVYLFLNTTDGRLSGSVEANTGTYTFPVVVNGVYTVPYTVVVTELPSQDLVVTVYKHASSVYMTQVLGPATYSLPNFVTYDTDPGVNRVPVYLFLNTTDGRLSGSVEANTGTYTFPVVVNGVYTVPYTVVVTELPSQDLVVTVYKHASSVYMTQVLGPATYSLPNFVTYDTDPGVNRVPVYLFLNTTDGRLSGSVEANTGTYTFPVVVNGVYTVPYTVVVTELPSQDLVVTVYKHASSVYMTQVLGPATYSLPNFVTYDTDPGVNRVPVYLFLNTTDGRLSGSVEANTGTYTFPVVVNGVYTVPYTVVVTELPSQV
>NC_004572.3|WP_011102426.1|276628_277975_+|16S-rRNA-(adenine(1518)-N(6)/adenine(1519)-N(6))--dimethyltransferase
MIHGHDYYSAVKRFVPYKRFGQHFVTDPNICNKIVTLAGVAPGDCVLEIGPGFGALTVALAKAKATVCGVEIDTRLFNALCKVIPAALSAPQPCTGQSHTDQPCDLGRLCDPHELPHRFTDERTDKLPTSQLHGLQVTSGSQHPTNQGVHDTGLRDTHKSDTHNATPRDRALLHDPGLHDTGLQGDVTQGYMTQGVRHSTNLNSANQHSDRQYSDDQSGDGQHSTVEESILEAEKLSIAARTNTHSTDTRHDNTHEHMRKWGEVYLINDDALKLRALPITPKMLVANLPYNIAVPLIMHVLQQFPSIVSATIMLQSEVADRICAKPPSRSAGAVTAKAAWFGHWKKVMKVARHVFYPIPGVDSVIVQFIRDEKSDCEVLREATFSLIEDAFSKRRKMLRQSLRYIPQADFVAAGIDPMLRAENLSVDNFMNLAKRRVYSTGRNLTHLA
>NC_004572.3|WP_080502114.1|280118_280712_+|putative-Ig-domain-containing-protein
MQSSRGFFGSITSDLGGVLLGGIAGIITGLLGSSTAPSLSNQATGVSIGQNSITITPKTTGYITSYTVTNTGVTSGGTGANGLPKGLSIDTTKGEITGSIDTGVSQGIYTVVVTGTAPTVTNNATTLTSTIVSATYTFLVTSTTPGLSGTATGVSIGQNSITITPNARGSPSSYAVTPINVIYGRCYIRWNWCKWST
>NC_004572.3|WP_080502098.1|280656_281118_+|putative-Ig-domain-containing-protein
MLYMADATSGGTGANGLPKGLTLNTTNGTITGSIDTSVSQGIYTVVVTGTAPTVTNNATTLTSTIVSATYTFLVTSTTPGLSGTATGVSIGQTNITITPKTTGYITGYTVTTYTHVNLVYTMDAKGVDTACLICLYWWVPDWLLMEARIFMER
>NC_004572.3|WP_038103833.1|285099_286803_+|dihydroxy-acid-dehydratase
MSSDANACEIDIKPRSRVVTHGIEATTSRGMLRAVGMGDADWEKPQIGIASSWNNITPCNLSLDRLAQGAREGVHAAGGYPLQFCTISVSDGISMGHEGMHFSLVSREVITDSVETVLMAEALDGVVLLAGCDKSLPGMLMAAARLDVSAVFLYAGSIAPGYVTLKCGESKEVTIIDSFEAVGAYKAGLIDQDDLGRIERAICPGEGACGGMYTANTMASVAEALGMSLLGSASPPSADRRRDVYAHKSGEAVVELLKRGITARDILTKEAFENAIAVVMALGGSTNAVLHLLAIAHEAHVPLTIDDFNKIGNRVPHIADLKPFGRYVMNDVDRVGGIPVVINALMREGFIHGDVITVSGRTMAEEISDINPGLPDGKVIHSFSSPLHPTGGIKVLKGTLAPDGAVAKTAGFDTVVFQGPAMVFDRERAAMDALSAGNIKKGSVIVIRYEGPKGGPGMREMLAITAAIKGSGLGKDVLLLTDGRFSGGTTGLCIGHIAPEAVDLGPIAFVQDGDIIRVDIEKSGIDVLVDEKQLRARHLTPPPPRYTSGVLSKYSKLVKSASLGAIT
>NC_004572.3|WP_011102428.1|286847_288593_+|acetolactate-synthase-large-subunit
MVRISGAQAVIKSLEELGIDLVFGIPGGAILEVYNSLFSSSIRHILVRHEQGAGHAAEGYACSSGKLGVCLATSGPGATNLVTAIADAYMDSVPILAITGQVYSHLLGSDAFQESDIIGITMPITKHAFSVKRATEIPAAIFAGAKIATTGRPGPVLIDITKDAQQDEFDFMWPPKSIDLSGYSVAQNIPDTLAQFADGFFDMLSGSIRPVIYAGGGTVRSGASEELIRFAEGFGIPVVTTLTARGVLPDSNRLNLGMPGMHGTVAAILALQKSDLLIALGTRFDDRVTGRLDSFAQNARVVHVDIDPAEIGKNRRPDLFVIGDVKEVLGYINSHSENKTTGDLTAWWRSLEKMRQIYPLVFPQKSSDGNLSPGYVIKRLGELSGPDAIYATGVGQHQMWASQAISFSRPNSFLTSGGAGTMGYAVPAAMGAKAANPEKIVWAIDGDGCFQMTNQELATCSVNGLPIKVAVINNRSLGMVRQWQGLFYNKRYSQTDLNTGDAYIPDFCKLAESYSCASCRVSSVDEVDNAIEFALAINDRPVVIDFVVCKDSMVWPMVPQGLGNSHLKYLQDVSPVWHDNE
>NC_004572.3|WP_011096512.1|288585_288828_+|acetolactate-synthase-small-subunit
MNRDVTISVLAKDTPGLLARLSCVFSRRGKNIISFSAVRDLDKIGFSRITIVCDPENIDQIIKQLNKLVDVLDARLDNYG

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Crispr_ID: NC_004572_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_004572_2

511338-511527

Orphan

Consensus_repeat	Method
AGCAGAGCTTGAAGCAGAACTTGCGGGACTTAGGCAA	PILER-CR

2 spacers

The CRISPR arrays of NC_004572_2

>merge|NC_004572|2|511338-511527|PILER-CR
AGCAGAGCTCGAAGCAGAACTTGCGGGACTTAGGCAAAATTTTGATGATGAAAGGAGACAAAGACTGCAAGAGCTTGAAGCAGAACTTGCGCAGAAGAGGTCTGCCGGTGAAGCGGAAATCGAGGAGCTAACACAGCGATCTGGAATAATCCGAGCAGAGCTTGAAGCAGAACTTGCGGGACTTAGGCAA

>NC_004572|2|1|511338-511527|PILER-CR
AGCAGAGCTCGAAGCAGAACTTGCGGGACTTAGGCAA	AATTTTGATGATGAAAGGAGACAAAGACT
GCAAGAGCTTGAAGCAGAACTTGCGCAGAAGAGGTCT	GCCGGTGAAGCGGAAATCGAGGAGCTAACACAGCGATCTGGAATAATCCGAGCAGAGCTTGA
AGCAGAACTTGCGGGACTTAGGCAA

Protein	Signature genes	Signature genes Name	Protein_function
NC_004572.3\|WP_011102562.1\|504021_504324_-\|aspartyl/glutamyl-tRNA-amidotransferase-subunit-C	unknown	unknown	gnl\|CDD\|178810
NC_004572.3\|WP_011096292.1\|521918_522437_-\|F0F1-ATP-synthase-subunit-B	unknown	unknown	gnl\|CDD\|180240
NC_004572.3\|WP_011096296.1\|516998_518423_-\|F0F1-ATP-synthase-subunit-beta	unknown	unknown	gnl\|CDD\|236447
NC_004572.3\|WP_011096293.1\|521140_521929_-\|F0F1-ATP-synthase-subunit-delta	unknown	unknown	gnl\|CDD\|237387
NC_004572.3\|WP_011096310.1\|500034_500991_+\|endonuclease/exonuclease/phosphatase-family-protein	unknown	unknown	gnl\|CDD\|377028
NC_004572.3\|WP_155105139.1\|499156_499711_-\|ECF-transporter-S-component	unknown	unknown	gnl\|CDD\|378252
NC_004572.3\|WP_011096294.1\|519501_521130_-\|F0F1-ATP-synthase-subunit-alpha	unknown	unknown	gnl\|CDD\|236448
NC_004572.3\|WP_011096295.1\|518471_519482_-\|F0F1-ATP-synthase-subunit-gamma	unknown	unknown	gnl\|CDD\|235535
NC_004572.3\|WP_011096300.1\|513050_513989_-\|cation-transporter	unknown	unknown	gnl\|CDD\|224151
NC_004572.3\|WP_011102565.1\|507437_508589_-\|aminotransferase-class-V-fold-PLP-dependent-enzyme	unknown	unknown	gnl\|CDD\|224029
NC_004572.3\|WP_044143924.1\|508585_510262_-\|hypothetical-protein	unknown	unknown	unknown
NC_004572.3\|WP_011096298.1\|516268_516541_-\|30S-ribosomal-protein-S15	unknown	unknown	gnl\|CDD\|180170
NC_004572.3\|WP_011096297.1\|516712_516997_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|376940
NC_004572.3\|WP_011102561.1\|502550_504125_-\|Asp-tRNA(Asn)/Glu-tRNA(Gln)-amidotransferase-subunit-GatA	unknown	unknown	gnl\|CDD\|234572
NC_004572.3\|WP_011102558.1\|497541_499089_-\|ATP-binding-cassette-domain-containing-protein	unknown	unknown	gnl\|CDD\|213192
NC_004572.3\|WP_011102564.1\|506335_507415_-\|tRNA-2-thiouridine(34)-synthase-MnmA	unknown	unknown	gnl\|CDD\|234664
NC_004572.3\|WP_011102569.1\|514016_516233_-\|polyribonucleotide-nucleotidyltransferase	unknown	unknown	gnl\|CDD\|131743
NC_004572.3\|WP_011096301.1\|511987_513067_+\|AI-2E-family-transporter	unknown	unknown	gnl\|CDD\|223701
NC_004572.3\|WP_011102560.1\|501039_502554_-\|Asp-tRNA(Asn)/Glu-tRNA(Gln)-amidotransferase-subunit-GatB	unknown	unknown	gnl\|CDD\|235489
NC_004572.3\|WP_033799964.1\|504462_506349_-\|NAD-dependent-DNA-ligase-LigA	unknown	unknown	gnl\|CDD\|236137

Protein	Function_ID	Function_description	E-value
NC_004572.3\|WP_011102562.1\|504021_504324_-\|aspartyl/glutamyl-tRNA-amidotransferase-subunit-C	gnl\|CDD\|178810	PRK00034, gatC, Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatC.	7.22196e-09
NC_004572.3\|WP_011096292.1\|521918_522437_-\|F0F1-ATP-synthase-subunit-B	gnl\|CDD\|180240	PRK05759, PRK05759, F0F1 ATP synthase subunit B; Validated.	4.899e-32
NC_004572.3\|WP_011096296.1\|516998_518423_-\|F0F1-ATP-synthase-subunit-beta	gnl\|CDD\|236447	PRK09280, PRK09280, F0F1 ATP synthase subunit beta; Validated.	0
NC_004572.3\|WP_011096293.1\|521140_521929_-\|F0F1-ATP-synthase-subunit-delta	gnl\|CDD\|237387	PRK13430, PRK13430, F0F1 ATP synthase subunit delta; Provisional.	2.40963e-28
NC_004572.3\|WP_011096310.1\|500034_500991_+\|endonuclease/exonuclease/phosphatase-family-protein	gnl\|CDD\|377028	pfam03372, Exo_endo_phos, Endonuclease/Exonuclease/phosphatase family. This large family of proteins includes magnesium dependent endonucleases and a large number of phosphatases involved in intracellular signalling. This family includes: AP endonuclease proteins EC:4.2.99.18, DNase I proteins EC:3.1.21.1, Synaptojanin an inositol-1,4,5-trisphosphate phosphatase EC:3.1.3.56, Sphingomyelinase EC:3.1.4.12, and Nocturnin.	2.08922e-15
NC_004572.3\|WP_155105139.1\|499156_499711_-\|ECF-transporter-S-component	gnl\|CDD\|378252	pfam09819, ABC_cobalt, ABC-type cobalt transport system, permease component. Members of this family of prokaryotic proteins include various hypothetical proteins as well as ABC-type cobalt transport systems.	2.15335e-27
NC_004572.3\|WP_011096294.1\|519501_521130_-\|F0F1-ATP-synthase-subunit-alpha	gnl\|CDD\|236448	PRK09281, PRK09281, F0F1 ATP synthase subunit alpha; Validated.	0
NC_004572.3\|WP_011096295.1\|518471_519482_-\|F0F1-ATP-synthase-subunit-gamma	gnl\|CDD\|235535	PRK05621, PRK05621, F0F1 ATP synthase subunit gamma; Validated.	9.51063e-104
NC_004572.3\|WP_011096300.1\|513050_513989_-\|cation-transporter	gnl\|CDD\|224151	COG1230, CzcD, Co/Zn/Cd efflux system component [Inorganic ion transport and metabolism].	4.95308e-66
NC_004572.3\|WP_011102565.1\|507437_508589_-\|aminotransferase-class-V-fold-PLP-dependent-enzyme	gnl\|CDD\|224029	COG1104, NifS, Cysteine sulfinate desulfinase/cysteine desulfurase and related enzymes [Amino acid transport and metabolism].	8.09545e-94
NC_004572.3\|WP_033799964.1\|504462_506349_-\|NAD-dependent-DNA-ligase-LigA	gnl\|CDD\|236137	PRK07956, ligA, NAD-dependent DNA ligase LigA; Validated.	0
NC_004572.3\|WP_011096298.1\|516268_516541_-\|30S-ribosomal-protein-S15	gnl\|CDD\|180170	PRK05626, rpsO, 30S ribosomal protein S15; Reviewed.	2.38521e-44
NC_004572.3\|WP_011096297.1\|516712_516997_-\|hypothetical-protein	gnl\|CDD\|376940	pfam02823, ATP-synt_DE_N, ATP synthase, Delta/Epsilon chain, beta-sandwich domain. Part of the ATP synthase CF(1). These subunits are part of the head unit of the ATP synthase. The subunit is called epsilon in bacteria and delta in mitochondria. In bacteria the delta (D) subunit is equivalent to the mitochondrial Oligomycin sensitive subunit, OSCP (pfam00213).	1.65841e-12
NC_004572.3\|WP_011102561.1\|502550_504125_-\|Asp-tRNA(Asn)/Glu-tRNA(Gln)-amidotransferase-subunit-GatA	gnl\|CDD\|234572	PRK00012, gatA, Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatA.	0
NC_004572.3\|WP_011102558.1\|497541_499089_-\|ATP-binding-cassette-domain-containing-protein	gnl\|CDD\|213192	cd03225, ABC_cobalt_CbiO_domain1, First domain of the ATP-binding cassette component of cobalt transport system. Domain I of the ABC component of a cobalt transport family found in bacteria, archaea, and eukaryota. The transition metal cobalt is an essential component of many enzymes and must be transported into cells in appropriate amounts when needed. This ABC transport system of the CbiMNQO family is involved in cobalt transport in association with the cobalamin (vitamin B12) biosynthetic pathways. Most of cobalt (Cbi) transport systems possess a separate CbiN component, the cobalt-binding periplasmic protein, and they are encoded by the conserved gene cluster cbiMNQO. Both the CbiM and CbiQ proteins are integral cytoplasmic membrane proteins, and the CbiO protein has the linker peptide and the Walker A and B motifs commonly found in the ATPase components of the ABC-type transport systems.	2.14053e-52
NC_004572.3\|WP_011102564.1\|506335_507415_-\|tRNA-2-thiouridine(34)-synthase-MnmA	gnl\|CDD\|234664	PRK00143, mnmA, tRNA-specific 2-thiouridylase MnmA; Reviewed.	1.72777e-174
NC_004572.3\|WP_011102569.1\|514016_516233_-\|polyribonucleotide-nucleotidyltransferase	gnl\|CDD\|131743	TIGR02696, polyribonucleotide_nucleotidyltransferase, guanosine pentaphosphate synthetase I/polynucleotide phosphorylase. Sohlberg, et al. present characterization of two proteins from Streptomyces coelicolor. The protein in this family was shown to have poly(A) polymerase activity and may be responsible for polyadenylating RNA in this species. Reference 2 showed that a nearly identical plasmid-encoded protein from Streptomyces antibioticus is a bifunctional enzyme that acts also as a guanosine pentaphosphate synthetase.	0
NC_004572.3\|WP_011102560.1\|501039_502554_-\|Asp-tRNA(Asn)/Glu-tRNA(Gln)-amidotransferase-subunit-GatB	gnl\|CDD\|235489	PRK05477, gatB, Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatB.	0
NC_004572.3\|WP_011096301.1\|511987_513067_+\|AI-2E-family-transporter	gnl\|CDD\|223701	COG0628, yhhT, Predicted permease, member of the PurR regulon [General function prediction only].	5.06847e-33

>NC_004572.3|WP_044143924.1|508585_510262_-|hypothetical-protein
MYARFYCLGFGVLVLRLKISVFCLLFAGIFLLASAVLQQLFFVELFGYKKDHFSTSSGYILLRENELFEQPDMSVQVSITPRGNPEPFEKSAGIYTAYSSEIQEWLKHYSYSVFDFAANTLSLGGSGKDPMSFLARNRDFFISQELPDKNGRIRLNPPRGVSVLLQIPGPAMVEVVRITPMAGLFMWLPLIVGLLLITLGLIVYVWSKFKSKRNPYGRRSTYISGYTKRRPLRHFFTFIICLPLVAGTSIACGSDKDNISSLELLREMHAHKIAKRVVETLHVADSRLSDPQSAMAGTALRLRQAAYKVLRKNKNAKVDLPAFDTAASVRLILPENTKSWPRVLLLVIDSSDGPSGEKLPPLAVLLRQNNPLDNYLIEYLARLTPNIVLPKLPTAEDGSILVRPESKLLAVQPSDIIAKYRAMLNTAGSSKLFDQSADILASQIRSSRSAKQKSLAGNSIIIFRDRQSGQIGMTTANGGALVFVDMLELERVIPSGGYSIVPQSGGEVSLLSGIVSSLRGIETTYSSQLLFYIPTVGSNERIALLGFTRGIASAREVR
>NC_004572.3|WP_011102565.1|507437_508589_-|aminotransferase-class-V-fold-PLP-dependent-enzyme
MMFGTYLDYAAHAPLMPEAAAVYQEFCNMPGNASSSHFYGRHMRAVIEKAKEGILTALNAPPGTEVSFTSGGTESINTCIYGTYLFRNSFVSHINDGNISKKIILANPADHTAQLSSIKSLPYAEIVWLPIDKYARVLPDSLEQAILQKDPNKIALFACTWVNSELGTISPVYDYARICQTYDIPVHIDSVAATSLIDFSRLVGKVSLSIAGHKIGAPPGTGAILSSFSFPPLLRGGNQQRLRSGSVDPLGSTSLSIALNRKVQSLRALRQRLVEVVLSAVPEAVVNSDTQDSSDAILNVSFPGCSSDTLLYLFDEAKIAISSGSACHSGVIQPSHVMSAVGLKPDLAKATLRFSLGWASTFDDIEVLSQNLGDIYKKALIAK
>NC_004572.3|WP_011102564.1|506335_507415_-|tRNA-2-thiouridine(34)-synthase-MnmA
MKVLAAMSGGVDSAVAAARAVDMGHDVVGVHLALSRSASGKRGCCTPRDAQDAAQAAQAIGIPFYVWDFSEEFQEKVIDNFISEYSAGRTPNPCLRCNEHIKFSSLLRRALALGFDAVCTGHYARVFLDEDGTYQLHRASSWAKDQSYVLAVLQQAQLKHCYFPLGATPSKKLVRQEADERGLKVSKKPDSHDVCFIPSSNTGAWLSQRIGRRDGDIIDDLGQRVGSHTGAFAYTVGQRKGLRLSSPAWDGKPRYVLDIEPISNTVVVGPRESLRVDELSGAFTTTGWCFTSRPIECSVQVRAHSDPVSAIAFIRDDVLVVRPDEPVFAVAKGQSAAIYRGTRVLGQLMIDNTKKYASS
>NC_004572.3|WP_033799964.1|504462_506349_-|NAD-dependent-DNA-ligase-LigA
MPHPDGDLDRRIELLTAQIIAARKAYYQENTSLMSDVEYDALEHELKDAEHAKGFSDRNSPSLTVGIAAQLNLFEPVKHIEPMLSLDNVFSLDQLHSWYEKTKKICPEGDQCTFVCELKIDGVGVSLRYANGYLISAATRGDGAIGEDITQNMLYVPSIPPRIALPGIFEIRGEAFIKRDEFDRINQLSLERSKQFANPRNFVSGCIRTKTPNMRYLESISFYAHGFTQVYGYTSGGMNLHSDITASGGVKTEIEHGMFSAYSRLSECKIPVNSYNRLCTNFSEIESYIENIRLNRQCVPYAIDGIVVKIDSLQKQALLGSTTKAPRWAVAYKFPSESTVTRLLDIEVSVGRTGRVTPYAVLQPIQLDGSEVSRATLHNQKVIGDKDLLIGDYVRIRKAGDIVPEVLCALPEKRDGSEVLFKMPSLCPSCGAELMPSKLGDIDLRCPNMQSCLVQLAGRLEYIGSRGVLDIAYLAEENAYALSHLRKFGKSAEVQLFKITIDDLVALEFMYKGNMRSPFRKKGDSFPGFEEPTKSAQDMVDSIERAKRSPLWKFLLALNIRHIGPASAKALADHFGSIESIINAKIDELLKVRSLGETIAISVHDWFRDPWRVELVNTWRSDGALFGH
>NC_004572.3|WP_011102562.1|504021_504324_-|aspartyl/glutamyl-tRNA-amidotransferase-subunit-C
MSISIDQVKSLARLACIDVTDSEADVLSRELSQIIDRLGFVKNGISDKSITGDVSEPLSNNTGCFRHDTPGPVLDIAPVLSNGEDGMFRISAISGEDSAF
>NC_004572.3|WP_011102561.1|502550_504125_-|Asp-tRNA(Asn)/Glu-tRNA(Gln)-amidotransferase-subunit-GatA
MIRRAPFLILLRFCRMGKMACSGYPPFQGRIVLSEMPAHRLAALIRSKEVSALEVAESFIDNIEASDSRICAFLYTDFSYTRDVARRVDEELKSATKLSPLAGVPIAVKDMILTRDMPTTAGSKILEGWIPPYNATVIERISRARMPILGKTNQDEFGMGSSTEYSAYKTTRNPWDLSRTAGGSGGGSSAAVSASQAPLALGTDTGGSIRLPAHCTGTVGIRPTYGSVSRYGVIALASSFDQVGPCSSNILDAALLHEVIAGYDPADAVSIKDQDLNFSQAAYEGANRGISGVRLGFVNPSNWCNSKITDLFGRTLKSLESEGAVLHEVQFPNFDHAVQAYYLIMQAEASSNLSRYDSIRFGPQEMAASASGTVSKTRSIRFGPEVKRRILLGTHILSAGYYDDFYMSAQKIRLLVKRDFAKIFSLVDVLLLPTAPTPAFKLGEKIDHHTSMYKSDTATTPASLAGLPAGSIPMGVIDGLPVGLQIIAPGQFDSRVYSTGAAIEQIIGDIHAMKNTKHNTGQTA
>NC_004572.3|WP_011102560.1|501039_502554_-|Asp-tRNA(Asn)/Glu-tRNA(Gln)-amidotransferase-subunit-GatB
MSEVVTYEDALKDFEPIIGLEVHVELSTQTKLFSSAPNIAGPLASCASQGPNTLVTPVCLGLPGSLPTVNERAVDYGIALGLALGCSIADELIFARKNYFYPDLPKNYQISQFDSPLAYDGKLEVETESGDVFFVEIERAHLEEDAGKLAHKSSTGRIQGAQYSLIDYNRSGVPLVEIVSRPVFADRCAPQVARVFVELIREIVLSLGVSNARLERGNIRCDANVSLRPRGLGAGILPNRTETKNLNSLRSIERAIRYEIQRQATLISSGELVRQETRHWREDRGITLSGRVKADSHEYRYFPEPDLLPIPIPSDKVEAIRLSMPEHPLALRRRLKAEWKFSDLQFRDVLNSSVLKQVDETVRAGATPDGAKKWWTGEITRIASQRRCNASDLISPEAVAEIELLISKGILNDSLARKVLAAVIDESLSVQQAIEKYDLSLTESASVERVLEKVLSENQEVVQKVISGKTQAVGVLVGSCMKALGGKADASKLRQTILNRLLPR
>NC_004572.3|WP_011096310.1|500034_500991_+|endonuclease/exonuclease/phosphatase-family-protein
MIKKIFLICFFVSCSALFFISDTLPEQVRYISQDFLPWLIVPILIFLVPSLIRFSLIPSLVGTITVIFWATQIGISALPSGESQVPDLTIVTQDMNSEASVSEAQTTHRSRNNSPPDNINRDVKTLLESNPDIIALQGIKNAAIGTLVGSLSPSFPFWHIFGTVGIWSKKPLENAVMLQLGSKLTSAGKIDIKISKEQTVRMYVVSLRKNQLDRLAQDEYEGMIKDLSVYLSQENSEKLIVVGGFGMSARDSRFKKLLKNNLKDMHTASWGFDFTWPSVFPLIDLDHILSTGFTATGGKLIHLEGSDHKGILMGLKHT
>NC_004572.3|WP_155105139.1|499156_499711_-|ECF-transporter-S-component
MIRRVIDIVYATVLSVVYALILLSLNYAYGLLSLLFSILPGISGVLTGLFVLGGPLGGIIVRKPGAAVFVSTLGALIESTLGVQWGWLNLLYGFAQGLAAETIFLICCYRIYTPFIAILSGLSAVSSGLFVEIILAALLEHTSLYIVIYVSTSLISGAAIGIFSWKIYLALKKSGALDPLDTFK
>NC_004572.3|WP_011102558.1|497541_499089_-|ATP-binding-cassette-domain-containing-protein
MSNPNIVATQSAIREDVEISNWSFSHSGETIINNLSLSIRQGERVLIIGPSGCGKSTLLLALAGLVHGFRGSILIGGEQPAPDQTAFVMQDPDSQVIFPNIGDEVAFPLELTMPNRRDIWEAVSMGLKSVGLSLPTTTQSDKLSHGQKQCLSIACAFASCPKILLLDEPLASLDKNSTEQVLKCFDSLFDVMGSSFAYTTFITGHDVEPWINRVDRVVVFNSKGSLSYDLPVGAIKNNKAILQKAGVFYKHRTLGNRSGPRTLHDSNRPVIMEVTNLAVTRGKNNLFENVTFQVHSGECIAIIGPNGVGKTSILLTVSGLMRAKRGDIFFECCMHDSRGRCQYSCGMNRDILTHTSPCGSFRNMHPPARCIKKPRHMARNLRKHTAIVMQNPEHQFLASSVDRELALGKGNCFGNDDLLERLNLLDAKSLNPFTLSWGQKRRLALAISVSMRPRILLLDEPLVGQDADISDQIVDFLIDLKLKGLGILIATHSKPLIDALADRVMELKAGEIAWK
>NC_004572.3|WP_011096301.1|511987_513067_+|AI-2E-family-transporter
MSRIDTSNNDKRTAGVFHIYQPFLTGFRATLGVGLGILCCLLILRMGVLFAYIGLALFITLAIEPLISALVKLGISRGVSVVLLLLFFSAFLGVALWLIIPILTSETALLWKTVSSFMTEGNYRQFISLLRKAIPDFDFNELLQQGWLWIQNNVTTITGSVVNIGIGIVNTVTGIVIVLILTIYFSATLPTIKATGYKLVPASRREFVKDTLEDVLSSVGRYTAGQFLLASINGTLTLLIFSILQFKYPILMAFIAFIGSMIPLVGTISSSALISGITLFSAQGWTVWAVVIYYLVYMNVEAYVISPKIMKKAVSVPGSLVVISALAGGMLAGVPGAVVAVPAAASIVVLIKRVLIDAK
>NC_004572.3|WP_011096300.1|513050_513989_-|cation-transporter
MFGVLLHGHTHSSFDVHINVSIYKRLFIALCLTVGFTLIELLAVYLSASVTLASDAGHMFIDSLGLFNALIAARLVAKSNRNSHRTYGLYRVEVFSAGVSILIMFFLAFLIAKESIMRLVYPEEHISGWVIFVTGIAGLLVNLSAVLVLHSAKQKGINLRAAYMEVLSDAIASVSVMLSAILIILTGLTIIDSIAAIAIVLFICYRAAKLGKEVIRILLQASPVDIQEVESSLLGIDGVISVDHLHAWTLSDEKHIATANILIHKQTDQNKVLVEAERILYEQYGILHTTLQISPMRLESRLACGGPVISHR
>NC_004572.3|WP_011102569.1|514016_516233_-|polyribonucleotide-nucleotidyltransferase
MDDVQFSEGVIDNGRFGTRTIRFETGRLARQAQGSVVAYLDGETMLLSSTSVGKQPKEDCDFFPLTVDVEERSYAAGKIPGSYFRREGRPSTEAILACRLIDRPLRPSFNAGLRNEVQVIVTVLSIAPGEFYEALAINAASASTLVSGLPFSGPIGGVRLALIDGQWVAFPRYEDLSGAVFDLTVAGRVFVNESGKEDIAIMMVEAEATESAWDLIHSHGAKKPNEEVIEEGIESAKVFIRTLCDIQRDLASKLSLSHTEPDLYPDYSDSVHSFVEGLVKSDLEKVYRGNHDSGYAPNALSASDEIKQKAYDAFHDAVLSGRFDQDSLSQFPHAYKAVLKDVVRTCVLEGFARMDGRGLSDIRPLDAEVQVVPRVHGSAVFQRGETQVLGVTTLNMLKMEQQIDSLAPIVSKRYIHHYNFPPYSTGEVGRVGSPKRREIGHGFLAERALVPVLPSREDFPYAIRQVSEALGSNGSTSMGSVCASTLSLLNAGVPLRAPVAGIAMGLISGRVDGEMRYVTLTDISGSEDALGDMDFKVAGTSDFITALQLDTKLDGIPAHVLSEALAHARSARLAILDVLTRVIDSPDQMSEYAPRVVRVKIPVQKIGELIGPKGKVINSIQDETGAEISIEDDGTVYIGSSQADSSEKAVAMVNSIVNPVEPCVGSQFLGTVVKNMPFGSFISLVPGKDGLLHISEIRKMVDGRHLESVDEVLSVGQKVLVEVSKIDDRGKLCLVAVK
>NC_004572.3|WP_011096298.1|516268_516541_-|30S-ribosomal-protein-S15
MARKLDMDKGAIISEYGLSKGDTGSPEVQIALLTARIARLTQHLKEHSFDHHSRRGLMLMVGRRRRLLSYLHGVDVSRYRAILSNLGLRR
>NC_004572.3|WP_011096297.1|516712_516997_-|hypothetical-protein
MATFETKVVSAKSFSLTCSATLVVARTRAGEIGIMAGHEPLLAALVPGSVKIFDSVNSVRALKTGRGFLCMNNNVLEIVASDIEVDTLEQLHGA
>NC_004572.3|WP_011096296.1|516998_518423_-|F0F1-ATP-synthase-subunit-beta
MTGDAVGRIVRVTGSVVDVEFSRNNLPGVFNALKTRVNRSGKEIEITLEVAQHLGDDLVRTVAMQSTDGLIRGQEVLDTGGHITVPVGDATKGRVFNVVGEVLNSNGEDIKFDEYWSIHRKPPEFSLLESKTQLFETGIKVIDLLTPYVQGGKIGLFGGAGVGKTVLIQEMIQRVAQDHGGVSVFAGVGERTREGNDLIREMQDAGVFDKTALVFGQMDEPPGTRLRVALSALTMAEYFRDVQKQDVLLFIDNIFRFTQAGSEVSTLLGRIPSAVGYQPNLADEMGVLQERITSTRGHSITSLQAIYVPADDYTDPAPATTFAHLDATTELSREIASKGLYPAVDPLASTSRILDPKYIGKDHYRVAVTVKQILQRDKELREIIAILGIDELSEEDRVTVARARRIEQFLSQNTYMAKKFTGVDGSTVPLQETIDGFDAICRGDCDHIPEQAFFNVGGLEDVERKWSKLQKELG
>NC_004572.3|WP_011096295.1|518471_519482_-|F0F1-ATP-synthase-subunit-gamma
MGAQLRVYRGKAASASVTKKITSAMELIAASRIVRAREKCGAFAPYAAALSRAVSTVLSYSDERHPLITQIEHPRRSAILVFASDRGLAGSFNAQVMNEAVQLGDNLTERSIETDYYLIGRKAVNFFNFRKIPFVQSWIGSSERPTFEMAQEISRTIFSCFLPARQDNKHDLGAQVVEAENIDMPHTPDMGDMQNNTFRRKVDEVYIVFNRFVNLVNQVPTAFRLIPMEVVDEVSSSSNIQREHDRPVLPLYSFEPDVTSVLDELLKEYVESRVFDTLLQSATAKHAATQRAMKSASDNADKLIEKYTRLANNARQAEITQQISEIIGGAGALDSG
>NC_004572.3|WP_011096294.1|519501_521130_-|F0F1-ATP-synthase-subunit-alpha
MSKQPIITSEEVRGVIRNLLDSTLSAAREANEFEVGRVVDAADGVAHIEGLPALMASELVEFSNGTFGVTLNLDEDLAGVVVLGEFDGIVEGMDVRSTGRVLSIPVGDAFLGRVVDPLGRPVDGLGEVPHETYRELELQAAGVMQRRSVHEPIQTGIKAIDTMIPIGRGQRQLIIGDRQTGKTTIAIDTIINQKDNWSDPEKRVFCIYVAIGQKGSTIAGVKRVLEEAGCMEYTTIVATPASDPAGFKYIAPYSGSAIGQHWMYQGRHVLIVFDDLSKQAEAYRAISLLLRRPPGREAYPGDVFYLHSRLLERCAKLSDEMGGGSMTGLPIIETKANDISAYIPTNVISITDGQIFLQSDLFNANQRPAVDVGISVSRVGGDAQIKSIKKVSGMLKLELAQYRALEAFSMFASDLDAVSRRQLDRGARLSELLRQQQQSPYPVEDQVVSIWVGSNGYIDDIPLSDVLDFERDLLEYLRNRTSILDDLRTCGDLTDALLERLKEAVESFKNKVYFMRVDEREKDPLEDENIGQEELVRSRRAN
>NC_004572.3|WP_011096293.1|521140_521929_-|F0F1-ATP-synthase-subunit-delta
MPGSSSRSSLAHLRNRLSECSDLQSLYEVAVLLAISRRLRSSLVSRSLSCVSKQKLIAELTGKDPDAFICMAVSLRWSEPIDLLYAFEEMFIRASCTRRFADCRDFLDELFWVSSIVDSHKILDKTLSARFLPAYSKKQLISGVFAGAHEGTLAVLEYFACYMQKKRAFRECVFFAEKIVADELGAQIADVTTERPLSREQRDELVDVLSRRFKRRIILREVINEKVFGGVRVQVNHSVIDDTVAVHLNNLALSFGALETFS
>NC_004572.3|WP_011096292.1|521918_522437_-|F0F1-ATP-synthase-subunit-B
MKFAQPHNPLLPSVPDIVFSAIVLAIVLPFFWWFVIPRISKLLSDRSSLIEGKISEAASAHARALETLELRKQQLDEAKSEASQIRQEARDDAQLILQQARETADETAERVMLHAREQIQAEKAAALLSLRSEIATLALAAAGKAVSEKLDDDKKSRELVSASIAKMAEDAG

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity
NC_004572_1	1.1\|267656\|25\|NC_004572\|CRISPRCasFinder	267656-267680	25	NC_004572.3	268892-268916	1	0.96

1. spacer 1.1|267656|25|NC_004572|CRISPRCasFinder matches to position: 268892-268916, mismatch: 1, identity: 0.96

atgcgatatacaacccaaatagtca	CRISPR spacer
atgcgatatacaacccaaacagtca	Protospacer
*******************.*****

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NC_004572_2	2.1\|511375\|29\|NC_004572\|PILER-CR	511375-511403	29	MN693998	Marine virus AFVG_250M48, complete genome	21353-21381	7	0.759
NC_004572_2	2.1\|511375\|29\|NC_004572\|PILER-CR	511375-511403	29	MN694494	Marine virus AFVG_250M305, complete genome	9647-9675	7	0.759

1. spacer 2.1|511375|29|NC_004572|PILER-CR matches to MN693998 (Marine virus AFVG_250M48, complete genome) position: , mismatch: 7, identity: 0.759

aattttgatgatgaaaggagacaaagact	CRISPR spacer
gagagagaagaagaaaggagacaaagact	Protospacer
.*    ** ** *****************

2. spacer 2.1|511375|29|NC_004572|PILER-CR matches to MN694494 (Marine virus AFVG_250M305, complete genome) position: , mismatch: 7, identity: 0.759

aattttgatgatgaaaggagacaaagact	CRISPR spacer
gtgcttgatgatgaaagtatacaaagatt	Protospacer
.  .************* * *******.*

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

28321 : 35119

Escherichia_phage(33.33%)

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_011096002.1\|28321_28864_+	5-(carboxyamino)imidazole ribonucleotide mutase	A0A2P0VNU7	Tetraselmis_virus	3.7e-23	45.0
WP_011102305.1\|29088_29511_-	hypothetical protein	NA	NA	NA	NA
WP_011096004.1\|29814_30678_-	dTDP-4-dehydrorhamnose reductase	A0A1D8EQE2	Escherichia_phage	3.8e-30	37.5
WP_011096005.1\|30674_31658_-	dTDP-glucose 4,6-dehydratase	I7HTA3	Enterobacteria_phage	1.2e-75	44.7
WP_011096006.1\|31902_32526_+	dTDP-4-dehydrorhamnose 3,5-epimerase family protein	H9NC63	Sphingomonas_phage	1.8e-13	32.4
WP_011096007.1\|32581_33460_+	glucose-1-phosphate thymidylyltransferase RfbA	A0A291LA53	Escherichia_phage	2.5e-90	57.2
WP_011096008.1\|33467_34316_-	glycosyltransferase family 2 protein	NA	NA	NA	NA
WP_011096009.1\|34312_35119_-	ABC transporter ATP-binding protein	Q9EMR9	Amsacta_moorei_entomopoxvirus	1.9e-12	25.9

DBSCAN-SWA_2

670348 : 679615

Indivirus(14.29%)

protease

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_011102659.1\|670348_671287_-	riboflavin biosynthesis protein RibF	A0A1V0SD03	Indivirus	1.3e-07	35.4
WP_011096139.1\|671319_672012_-	uracil-DNA glycosylase	U5U481	Elephant_endotheliotropic_herpesvirus	7.0e-35	38.9
WP_155105175.1\|672018_672696_-	ABC transporter permease	NA	NA	NA	NA
WP_155105176.1\|672784_673546_-	ATP-binding cassette domain-containing protein	A0A2H4PQG7	Staphylococcus_phage	3.5e-19	29.7
WP_155105146.1\|673770_674220_-	DUF3180 domain-containing protein	NA	NA	NA	NA
WP_011102663.1\|674212_676513_-	dihydropteroate synthase	A0A0B5J4J5	Pandoravirus	1.9e-20	31.8
WP_011096134.1\|676549_677095_-	GTP cyclohydrolase I	A0A1W7AF02	Streptococcus_virus	5.5e-19	37.3
WP_011102664.1\|677108_679109_-\|protease	ATP-dependent zinc metalloprotease FtsH	E5ESM9	Bathycoccus_sp._RCC1105_virus	1.3e-105	45.9
WP_011096132.1\|679111_679615_-	hypoxanthine phosphoribosyltransferase	A0A1V0SEQ1	Hokovirus	9.6e-10	28.6

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. NC_004572

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection