CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Target MGE spacer number	Prophage number
NC_004669	Enterococcus faecalis V583 plasmid pTEF1, complete sequence	0 crisprs	NA	0	1
NC_004668	Enterococcus faecalis V583, complete sequence	1 crisprs	DEDDh,csa3,cas3,cas14j,DinG,RT	0	14
NC_004670	Enterococcus faecalis V583 plasmid pTEF3, complete sequence	0 crisprs	NA	0	0
NC_004671	Enterococcus faecalis V583 plasmid pTEF2, complete sequence	1 crisprs	NA	4	0

Results visualization

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CRISPR-Cas detection and classification

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

5444 : 53567

Streptococcus_phage(55.56%)

bacteriocin,holin,transposase

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_001015311.1\|5444_6125_+\|transposase	IS6-like element IS1216 family transposase	A0A1X9I6C6	Streptococcus_phage	1.5e-127	99.6
WP_001038790.1\|6332_7070_+	23S rRNA (adenine(2058)-N(6))-methyltransferase Erm(B)	E4ZFQ0	Streptococcus_phage	1.4e-134	99.6
WP_001015311.1\|7582_8263_-\|transposase	IS6-like element IS1216 family transposase	A0A1X9I6C6	Streptococcus_phage	1.5e-127	99.6
WP_010730188.1\|8711_9035_+	quaternary ammonium compound efflux SMR transporter QacH	NA	NA	NA	NA
WP_025192524.1\|9847_10771_-	protein rep	NA	NA	NA	NA
WP_001015311.1\|10845_11526_-\|transposase	IS6-like element IS1216 family transposase	A0A1X9I6C6	Streptococcus_phage	1.5e-127	99.6
WP_010774254.1\|11563_12055_-	ABC transporter ATP-binding protein	NA	NA	NA	NA
WP_010708487.1\|12098_12233_-\|bacteriocin	LsbB family leaderless bacteriocin	NA	NA	NA	NA
WP_002387615.1\|12614_13304_-\|transposase	IS6 family transposase	A0A1X9I6C6	Streptococcus_phage	1.3e-54	48.7
WP_161797692.1\|13512_13665_+\|holin	putative holin-like toxin	NA	NA	NA	NA
WP_000615486.1\|13883_14360_-	single-stranded DNA-binding protein	A0A1S5PRS2	Streptococcus_phage	8.8e-21	49.5
WP_002387613.1\|15829_16585_-	hypothetical protein	A8ATL9	Listeria_phage	2.5e-17	44.6
WP_001245899.1\|16746_17013_-	hypothetical protein	A0A1W6JN36	Lactococcus_phage	2.0e-22	68.2
WP_001808764.1\|17019_17202_-	hypothetical protein	NA	NA	NA	NA
WP_010708485.1\|17619_18108_-	hypothetical protein	NA	NA	NA	NA
WP_002387611.1\|18113_18899_-	ArsR family transcriptional regulator	NA	NA	NA	NA
WP_002387610.1\|18895_19057_-	hypothetical protein	NA	NA	NA	NA
WP_011109603.1\|19756_21970_-	TraM recognition domain-containing protein	NA	NA	NA	NA
WP_011109604.1\|21956_24302_-	MAEBL family membrane protein	NA	NA	NA	NA
WP_002383639.1\|24319_24715_-	hypothetical protein	NA	NA	NA	NA
WP_011109606.1\|24671_27164_-	type VI secretion protein	NA	NA	NA	NA
WP_002365911.1\|27268_27727_-	single-stranded DNA-binding protein	Q9B008	Lactococcus_phage	6.6e-42	59.2
WP_002360791.1\|27883_28273_-	conjugal transfer protein	NA	NA	NA	NA
WP_002360793.1\|28272_28548_-	hypothetical protein	NA	NA	NA	NA
WP_002385553.1\|28537_29572_-	conjugal transfer protein	NA	NA	NA	NA
WP_002360796.1\|29564_29879_-	hypothetical protein	NA	NA	NA	NA
WP_002385554.1\|29878_30295_-	thioredoxin family protein	NA	NA	NA	NA
WP_010774160.1\|30278_30896_-	hypothetical protein	NA	NA	NA	NA
WP_010774159.1\|30898_32170_-	CHAP domain-containing protein	A0A1P8CMP9	Staphylococcus_phage	2.0e-11	37.3
WP_162781820.1\|32195_33053_-	LPXTG cell wall anchor domain-containing protein	NA	NA	NA	NA
WP_002365963.1\|33075_33954_-	hypothetical protein	NA	NA	NA	NA
WP_002370667.1\|33964_34225_-	hypothetical protein	NA	NA	NA	NA
WP_002364326.1\|34293_34680_-	hypothetical protein	NA	NA	NA	NA
WP_002379922.1\|34701_35055_-	pheromone response system RNA-binding regulator PrgU	NA	NA	NA	NA
WP_010785625.1\|35116_39007_-	LPXTG-anchored aggregation substance Asa1	NA	NA	NA	NA
WP_002360910.1\|39313_39649_-	DUF5406 domain-containing protein	F0PIH7	Enterococcus_phage	2.3e-39	69.4
WP_010713023.1\|40245_42918_-	surface exclusion protein SEA1/PrgA	NA	NA	NA	NA
WP_002365956.1\|42928_43234_-	hypothetical protein	NA	NA	NA	NA
WP_002365954.1\|43815_44172_-	hypothetical protein	NA	NA	NA	NA
WP_001015311.1\|44621_45302_-\|transposase	IS6-like element IS1216 family transposase	A0A1X9I6C6	Streptococcus_phage	1.5e-127	99.6
WP_002380753.1\|45921_47412_+	replication protein RepR	NA	NA	NA	NA
WP_000195429.1\|47518_48691_+\|transposase	IS256-like element IS256 family transposase	A0A0N9STL0	Staphylococcus_phage	3.5e-135	100.0
WP_000393259.1\|48747_49140_+	GNAT family N-acetyltransferase	A0A0N7GFH7	Staphylococcus_phage	6.9e-72	100.0
WP_001028144.1\|49140_50580_+	aminoglycoside O-phosphotransferase APH(2'')-Ia	A0A1X9I6C2	Streptococcus_phage	3.8e-285	100.0
WP_000195429.1\|50709_51882_-\|transposase	IS256-like element IS256 family transposase	A0A0N9STL0	Staphylococcus_phage	3.5e-135	100.0
WP_001015311.1\|52022_52703_-\|transposase	IS6-like element IS1216 family transposase	A0A1X9I6C6	Streptococcus_phage	1.5e-127	99.6
WP_002383791.1\|53041_53308_+	hypothetical protein	NA	NA	NA	NA
WP_002367773.1\|53297_53567_+	type II toxin-antitoxin system RelE/ParE family toxin	A0A1S5SCV8	Streptococcus_phage	3.3e-17	46.5

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

2. NC_004668

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CRISPR-Cas detection and classification

Crispr_ID: NC_004668_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_004668_1

3031984-3032057

Orphan

Consensus_repeat	Method
ATAGTTGGCGAGCAACAGAAAAAC	CRISPRCasFinder

1 spacers

The CRISPR arrays of NC_004668_1

>merge|NC_004668|1|3031984-3032057|CRISPRCasFinder
ATAGTTGGCGAGCAACAGAAAAACTCGATATAGAATTGGACGTAGAGCCAATAGTTGGTGAGCAACAGAAAAAC

>NC_004668|1|1|3031984-3032057|CRISPRCasFinder
ATAGTTGGCGAGCAACAGAAAAAC	TCGATATAGAATTGGACGTAGAGCCA
ATAGTTGGTGAGCAACAGAAAAAC

Protein	Signature genes	Signature genes Name	Protein_function
NC_004668.1\|WP_002354866.1\|3041100_3041472_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|226923
NC_004668.1\|WP_002354864.1\|3041560_3042358_-\|TIGR00282-family-metallophosphoesterase	unknown	unknown	gnl\|CDD\|379099
NC_004668.1\|WP_002359020.1\|3020332_3021199_-\|helix-turn-helix-domain-containing-protein	unknown	unknown	gnl\|CDD\|224343
NC_004668.1\|WP_002387396.1\|3034064_3035036_-\|ribose-phosphate-diphosphokinase	unknown	unknown	gnl\|CDD\|234929
NC_004668.1\|WP_002354877.1\|3027278_3027992_-\|trehalose-operon-repressor	unknown	unknown	gnl\|CDD\|274116
NC_004668.1\|WP_002378992.1\|3038523_3041100_-\|DNA-mismatch-repair-protein-MutS	unknown	unknown	gnl\|CDD\|235444
NC_004668.1\|WP_002387387.1\|3021366_3022671_-\|insulinase-family-protein	unknown	unknown	gnl\|CDD\|223685
NC_004668.1\|WP_002387394.1\|3031012_3031663_+\|beta-phosphoglucomutase	unknown	unknown	gnl\|CDD\|213672
NC_004668.1\|WP_002385181.1\|3032123_3032717_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|376232
NC_004668.1\|WP_002354883.1\|3024140_3024590_+\|large-conductance-mechanosensitive-channel-protein-MscL	unknown	unknown	gnl\|CDD\|376605
NC_004668.1\|WP_002387800.1\|3025444_3026155_-\|WxL-domain-containing-protein	unknown	unknown	gnl\|CDD\|372694
NC_004668.1\|WP_002387393.1\|3028253_3030998_+\|glycoside-hydrolase-family-65-protein	unknown	unknown	gnl\|CDD\|224471
NC_004668.1\|WP_002387390.1\|3026238_3026937_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|372694
NC_004668.1\|WP_002354863.1\|3042517_3044074_-\|ribonuclease-Y	unknown	unknown	gnl\|CDD\|237177
NC_004668.1\|WP_002354869.1\|3035780_3036335_-\|septum-formation-protein-Maf	unknown	unknown	gnl\|CDD\|238310
NC_004668.1\|WP_002378991.1\|3036359_3038492_-\|DNA-mismatch-repair-endonuclease-MutL	unknown	unknown	gnl\|CDD\|223400
NC_004668.1\|WP_002387388.1\|3022663_3023932_-\|insulinase-family-protein	unknown	unknown	gnl\|CDD\|223685
NC_004668.1\|WP_002399781.1\|3024630_3025347_-\|WxL-domain-containing-protein	unknown	unknown	gnl\|CDD\|372694
NC_004668.1\|WP_002354860.1\|3044470_3045517_-\|recombinase-RecA	unknown	unknown	gnl\|CDD\|236476
NC_004668.1\|WP_002354871.1\|3035210_3035648_-\|peptide-methionine-(R)-S-oxide-reductase-MsrB	unknown	unknown	gnl\|CDD\|234692

Protein	Function_ID	Function_description	E-value
NC_004668.1\|WP_002354866.1\|3041100_3041472_-\|hypothetical-protein	gnl\|CDD\|226923	COG4550, COG4550, Predicted membrane protein [Function unknown].	8.72333e-15
NC_004668.1\|WP_002354864.1\|3041560_3042358_-\|TIGR00282-family-metallophosphoesterase	gnl\|CDD\|379099	pfam13277, YmdB, YmdB-like protein. This family of putative phosphoesterases contains the B. subtilis protein YmdB.	2.68643e-155
NC_004668.1\|WP_002359020.1\|3020332_3021199_-\|helix-turn-helix-domain-containing-protein	gnl\|CDD\|224343	COG1426, COG1426, Predicted transcriptional regulator contains Xre-like HTH domain [Function unknown].	2.66641e-35
NC_004668.1\|WP_002387396.1\|3034064_3035036_-\|ribose-phosphate-diphosphokinase	gnl\|CDD\|234929	PRK01259, PRK01259, ribose-phosphate diphosphokinase.	0
NC_004668.1\|WP_002354877.1\|3027278_3027992_-\|trehalose-operon-repressor	gnl\|CDD\|274116	TIGR02404, Trehalose_operon_transcriptional_repressor, trehalose operon repressor, B. subtilis-type. This family consists of repressors of the GntR family typically associated with trehalose utilization operons. Trehalose is imported as trehalose-6-phosphate and then hydrolyzed by alpha,alpha-phosphotrehalase to glucose and glucose-6-P. This family includes repressors mostly from Gram-positive lineages and does not include the TreR from E. coli. [Regulatory functions, DNA interactions].	6.92052e-137
NC_004668.1\|WP_002378992.1\|3038523_3041100_-\|DNA-mismatch-repair-protein-MutS	gnl\|CDD\|235444	PRK05399, PRK05399, DNA mismatch repair protein MutS; Provisional.	0
NC_004668.1\|WP_002387387.1\|3021366_3022671_-\|insulinase-family-protein	gnl\|CDD\|223685	COG0612, PqqL, Predicted Zn-dependent peptidases [General function prediction only].	5.34847e-85
NC_004668.1\|WP_002387394.1\|3031012_3031663_+\|beta-phosphoglucomutase	gnl\|CDD\|213672	TIGR01990, bPGM, beta-phosphoglucomutase. This model represents the beta-phosphoglucomutase enzyme which catalyzes the interconverison of beta-D-glucose-1-phosphate and beta-D-glucose-6-phosphate. The 6-phosphate is capable of non-enzymatic anomerization (alpha <-> beta) while the 1-phosphate is not. A separate enzyme is responsible for the isomerization of the alpha anomers. Beta-D-glucose-1-phosphate results from the phosphorylysis of maltose (2.4.1.8), trehalose (2.4.1.64) or trehalose-6-phosphate (2.4.1.216). Alternatively, these reactions can be run in the synthetic direction to create the disaccharides. All sequenced genomes which contain a member of this family also appear to contain at least one putative maltose or trehalose phosphorylase. Three species, Lactococcus, Enterococcus and Neisseria appear to contain a pair of paralogous beta-PGM's. Beta-phosphoglucomutase is a member of the haloacid dehalogenase superfamily of hydrolase enzymes. These enzymes are characterized by a series of three catalytic motifs positioned within an alpha-beta (Rossman) fold. beta-PGM contains an inserted alpha helical domain in between the first and second conserved motifs and thus is a member of subfamily IA of the superfamily. The third catalytic motif comes in three variants, the third of which, containing a conserved DD or ED, is the only one found here as well as in several other related enzymes (TIGR01509). The enzyme from L. lactis has been extensively characterized including a remarkable crystal structure which traps the pentacoordinate transition state. [Energy metabolism, Biosynthesis and degradation of polysaccharides].	8.00327e-107
NC_004668.1\|WP_002385181.1\|3032123_3032717_+\|hypothetical-protein	gnl\|CDD\|376232	pfam18813, PBECR4, phage-Barnase-EndoU-ColicinE5/D-RelE like nuclease4. A predicted endoRNase of the Barnase-EndoU-ColicinE5/D-RelE like nuclease fold found in polyvalent proteins of phages and conjugative elements. The predicted active site contains a conserved histidine residue.	2.0486e-23
NC_004668.1\|WP_002354883.1\|3024140_3024590_+\|large-conductance-mechanosensitive-channel-protein-MscL	gnl\|CDD\|376605	pfam01741, MscL, Large-conductance mechanosensitive channel, MscL.	2.8499e-49
NC_004668.1\|WP_002387800.1\|3025444_3026155_-\|WxL-domain-containing-protein	gnl\|CDD\|372694	pfam13731, WxL, WxL domain surface cell wall-binding. The WxL motif appears in two or three copies in these bacterial proteins and confers a cell surface localization function. It seems likely that this region is the cell wall-binding domain of gram-positive bacteria, and may interact with the peptidoglycan.	5.10142e-16
NC_004668.1\|WP_002387393.1\|3028253_3030998_+\|glycoside-hydrolase-family-65-protein	gnl\|CDD\|224471	COG1554, ATH1, Trehalose and maltose hydrolases (possible phosphorylases) [Carbohydrate transport and metabolism].	2.12715e-173
NC_004668.1\|WP_002387390.1\|3026238_3026937_-\|hypothetical-protein	gnl\|CDD\|372694	pfam13731, WxL, WxL domain surface cell wall-binding. The WxL motif appears in two or three copies in these bacterial proteins and confers a cell surface localization function. It seems likely that this region is the cell wall-binding domain of gram-positive bacteria, and may interact with the peptidoglycan.	2.87509e-06
NC_004668.1\|WP_002354863.1\|3042517_3044074_-\|ribonuclease-Y	gnl\|CDD\|237177	PRK12704, PRK12704, phosphodiesterase; Provisional.	0
NC_004668.1\|WP_002354869.1\|3035780_3036335_-\|septum-formation-protein-Maf	gnl\|CDD\|238310	cd00555, Maf, Nucleotide binding protein Maf. Maf has been implicated in inhibition of septum formation in eukaryotes, bacteria and archaea, but homologs in B.subtilis and S.cerevisiae are nonessential for cell division. Maf has been predicted to be a nucleotide- or nucleic acid-binding protein with structural similarity to the hypoxanthine/xanthine NTP pyrophosphatase Ham1 from Methanococcus jannaschii, RNase H from Escherichia coli, and some other nucleotide or RNA-binding proteins.	1.6551e-85
NC_004668.1\|WP_002378991.1\|3036359_3038492_-\|DNA-mismatch-repair-endonuclease-MutL	gnl\|CDD\|223400	COG0323, MutL, DNA mismatch repair enzyme (predicted ATPase) [DNA replication, recombination, and repair].	0
NC_004668.1\|WP_002387388.1\|3022663_3023932_-\|insulinase-family-protein	gnl\|CDD\|223685	COG0612, PqqL, Predicted Zn-dependent peptidases [General function prediction only].	1.18101e-50
NC_004668.1\|WP_002399781.1\|3024630_3025347_-\|WxL-domain-containing-protein	gnl\|CDD\|372694	pfam13731, WxL, WxL domain surface cell wall-binding. The WxL motif appears in two or three copies in these bacterial proteins and confers a cell surface localization function. It seems likely that this region is the cell wall-binding domain of gram-positive bacteria, and may interact with the peptidoglycan.	3.31475e-23
NC_004668.1\|WP_002354860.1\|3044470_3045517_-\|recombinase-RecA	gnl\|CDD\|236476	PRK09354, recA, recombinase A; Provisional.	0
NC_004668.1\|WP_002354871.1\|3035210_3035648_-\|peptide-methionine-(R)-S-oxide-reductase-MsrB	gnl\|CDD\|234692	PRK00222, PRK00222, peptide-methionine (R)-S-oxide reductase MsrB.	2.48715e-93

>NC_004668.1|WP_002387394.1|3031012_3031663_+|beta-phosphoglucomutase
MTIGFIFDLDGVITDTAKFHYQAWKALADSLGIPIDETFNETLKGISRMDSLDRILVHGHRENAFTPAEKEALAQQKNDHYVQLLEQLTTEDVLPGVVPLLQQAQARHIPCAVASASKNAPLILEKLGVRAYFATIVDPDSLSKGKPDPEIFLAAADSIGVLPQNAIGFEDAQSGIDGLKAAGIYAVGLSASQPLIGADMQVSEMTELSVDALLNR
>NC_004668.1|WP_002387393.1|3028253_3030998_+|glycoside-hydrolase-family-65-protein
MSIQVHKEAPNMTILELTFATNQLTTTFFNHKLEPLHQKTFPFEALTIEETVPELCQLILAEAAPILGGIVADFPADFFSPEETLALVPQAVIQAFAEQLNTPLLTAAEQAAAPNLLEAFEEKRQYLAWHLDYYGYVPGKNEYAVESLLTVGNGFLGLRGTTPEMTISDDHYPATYIAGLYNTAASEVAGQVVENEDFVNAPDNQHIALKIGDATDWLTISPDTLQQLHRQLNLKTGLFVAEMILKDADNQQIKLTTKKIANMAQPNDYHLQYTFEPLNFSAPITLKTVTDGSVYNYNVARYRNLTAKHFQVTALSAQENKTVIEVCTNQSNLSVRETSLITGDFFEKEAITIQEEAEKIAQVVTVMAHQGTRYTLEKQVFVQASHAEQSWQVPFTPKDSFAAAAQESARAWQTLWQQANITVTGDLMSQKLLRIHSYHLLASASPFSNQAQALDVSITARGLHGEAYRGHIFWDEIFILPFYIQHYPDTAKQLLLYRYHRLEKAKENAAASQYRGAMYPWQSGRDGRETTQKLHLNPLNGHWGEDHSILQRHVSLAIAYNAWLYWHSTQDHEFMKQYGGEMLLEIAQFWNSAATLDDATGRFFIDKVMGPDEFHEGYPDQAESGLKNNAYTNLMVVWLFEELTNILALFSEEEQAQLFAKTQTTSADLARMQQIQNSLEIEVNSDGIIAQYEGYFGLKEIDWTAMKEKYGNIYRMDRILKAEGESPDDYKVAKQADTLMLFYNLDKTRVDQILEDLGYQLPADYLEKNLLYYLKRTSHGSTLSRIVHAQLAEMAQFHELSWQLYQEALYSDYRDIQGGTTAEGIHTGVMAATIHVTLATYAGVDTRQNELSICPNLPEHWQALAFQFIHQGVTYQFSLTQTSVTITADRDTQLLVQGALIPLTAERPKEVHYQ
>NC_004668.1|WP_002354877.1|3027278_3027992_-|trehalose-operon-repressor
MNKFHDIFLELEQQIVQGDYQPGDLLPSENQLVETYNVSRETIRKALNLLINAGYIQKKQGKGSIVLNFKKFNFPISGVTSYKELQQTQHIESHTHVVSLEEIPVERNLAQLTGWTEGAPVWRLVRQREIEGEVDILDIDYLIKEIVPELPKHRAEDSIFDYLENDLGLAISYAQKEITVEPLTEMDKQLIGEVEGNHVVVVRSIMNLEDTRCFGYTESRHRLNKFKFVEFARRRKL
>NC_004668.1|WP_002387390.1|3026238_3026937_-|hypothetical-protein
MMKKKMMASLLVGSAVVAASLAPLSAQAVTTGNTPVQVEFGGGTLDNETGNAGDNTAPDPTVPNTNFDLVKIPKAVTFNTTKISDSLQNISSTQQYLGYAIGDIRGTKEGWHVTASATLANGSEALAGNLNFSQIGYYSKFDATKQIYVYLTDAESLANYEADPTTPDFSGTNIPLSGDAIAIATASSGKGQGIWYSGIRTMNLEVTTPYQQIKAGAYTGNITWNLVAGPSI
>NC_004668.1|WP_002387800.1|3025444_3026155_-|WxL-domain-containing-protein
MKKKMMASLLVGSAVVGASLAPLSAQAVTTGNTPVTAEFAGGTLPDGNGVPNTVDPDPTKPNSNFDLLFIPREYDFGKLSISDDLTKPIPNKTDEGRAGNVESVGVGDIRGSKEGWHVTAQSTGMKLGEESLEGSITTGAMFLYPLIYNEETKTYDYQSADLADPVTKPETVDTTAFSIALGGDAVLLANATAGKGQGLWQFSFRPYLNITTPAYNIKAGAYTGNITWNLVAGPSI
>NC_004668.1|WP_002399781.1|3024630_3025347_-|WxL-domain-containing-protein
MKKKMMASLLVGSAVVGASLAPLSAQATTTGNTPVTAAFEGGTLPDGNGDANTVDPDPSGSNSNFDLLFIPREFNFGKLSISDDLTKPILNQRDPEATNGHTEMIGVGDVRGGKEGWHLTAQSNGLKLGTESLQGNIKVALITQLDLEYEATSNSYVALTTAVSTPEVRPQLAAPQNWTLDLGGEAQLMANAAAGQGQGLWQFSLFNTALNITTPANNIKAGAYTGSITWNLVAGPSV
>NC_004668.1|WP_002354883.1|3024140_3024590_+|large-conductance-mechanosensitive-channel-protein-MscL
MIKEFKEFIMRGSVLDLAVGVVIGSAFTAIVTQVVEGLITPLISLIFVLTTGKKSADDALGALVYKVEGVEFNIGSVISALITFLITAFVLFLIVKAANKMKNRGKKEEAAEEEVVPTSEDYLKEIRDLLAAQTPPAETVKTDSTFTEK
>NC_004668.1|WP_002387388.1|3022663_3023932_-|insulinase-family-protein
MSVQLVKGVNLHVIPTEKYKTVRLLVRFNTRLNHETITKRTLLSSLMETNSLNYPNQVKLSERLAELYGASFGIGVSKKGNQHWFNISMNIVNDHYLQDSQVLAEAVDFLKEIIFAPNIQAGQFEAETFQREKENLKAYLESIVEDKQTYASLALQSVYFNQSEDQKIPSFGTVAALAEETAASLAAYYQKMLAEDQVDIFVLGDVNEAELVPLFKQLPFTPREEGKAAIFYNQPIRNVIEERTEREVLAQSKLNLAYNTDIYYGDSYYFALQVFNGIFGGFPHSKLFMNVREKEHLAYYASSSIDTFRGFMTVQTGIDGKNRNQVLRLISTELENIRLGKIRELEIEQTKAMLKNQYILALDNAGAWLEKEYLNELMPQTMLTAEEWIARINAVTIPEIQEVAKRLELQAIFFLEGETEND
>NC_004668.1|WP_002387387.1|3021366_3022671_-|insulinase-family-protein
MIKKDYAQIKETLYTETLENGLKVYLLPKNDFQKTYGLFTTDYGSIDNTFVPIGQEEMIEVPDGIAHFLEHKMFEKEDGDVFQKFGQQGASANAFTSFTKTSYLFSTTDQVTQNLETLLDFVQSPYFTKETVEKEKGIIGQEIQMYLDDPNWRLFFGILGNLYPKHPLHIDIAGTVASIAEITAEDLYTCYNTFYHPSNMTLFVVGKMDPEALMAFIRENQAAKEFPAAQPIRRHFPEETAADIVKESAIEMTVTRAKVLVGLKGLDEVPTTGRDLMKYQVTVNLLLQLLFGNTSQNYLALYDEGLLDDSFSYDFNLDRSFHFADIGGDSEQPEVLAERIEAILLSATTSPELTEENLSLLKKKMIGKYFQSLNSLEYIANQFSQSLFGETTLFDKIEVIESIQLADVRQVAETFIREEGLSRFYMYPKGETEQ
>NC_004668.1|WP_002359020.1|3020332_3021199_-|helix-turn-helix-domain-containing-protein
MASVNIGETLKEARLQKNISIDELQQMTKIQKRYLEIIEQNDFESLPGTFYVRAFIRQYASAVGLDGNQLVDIYDGKEPAIVEEPKPVYEELEGSRKQLHDEEKQSSWLLRNLPAIAFSLIGLAIAVVVLYIMWQDQKAEPIIQTPATSASVEKPKESSQAPESSTQSSTPPSSSSEPEKKTAVAVVSDANNQVTATVKDANSPINITFKGTEGSCWIGVMVDGNYTYQHTLQAGETQTTALPANAANATLILGASNNVAIQVDGADLTLEKTPVLIRKDVTLGITYR
>NC_004668.1|WP_002385181.1|3032123_3032717_+|hypothetical-protein
MIEKKDFDTIRKAFLIYDTNFNNHMFTYTYQHRKTKKLLEMNVQFEAGNFMHLCGVDYYQIDKQGSCKFRFKATQFYRALKNNKVSLRGIKPKDDGTTGQKLQVIPLLEMLISPGVRICDGGKFYNLQYEKAIRSGKMIVALTCKENNKKYVPQSLLSLINQPRKSQSKSLTESHEVIKISKSELNSTSVIEVYDKF
>NC_004668.1|WP_002387396.1|3034064_3035036_-|ribose-phosphate-diphosphokinase
MSKHYFDPRLKIFSLNSNRPLAEKIADAVGVELGKCSVTQFSDGEIQVNIEESIRGAHVYVIQSTSSPVNDNLMELLIMIDALKRASAKTINVVMPYYGYARQDRKARAREPITAKLVANMIEKAGATRMLTLDLHAVQIQGFFDIPVDHLMGAPLIADYFIEHGIQGDDVVVVSPDHGGVTRARKLAEFLKAPIAIIDKRRPKANVAEVMNIIGHVEGKTCVLIDDMIDTAGTISLAANALKEAGAKDVYASCTHPVLSGPALQRIEDSAIERLVVTDSIYLSDDRKIVKIDEVSVGELIGDAIKRIHENKPVSPLFETKNK
>NC_004668.1|WP_002354871.1|3035210_3035648_-|peptide-methionine-(R)-S-oxide-reductase-MsrB
MTKPTEEELKQTLTDLQYAVTQENATERPFSGEYDDFYQDGIYVDIVSGEPLFSSLDKYDAGCGWPSFTKPIEKRGVKEKADFSHGMHRVEVRSQEADSHLGHVFTDGPLQEGGLRYCINAAALRFVPVADLEKEGYGEYLSLFK
>NC_004668.1|WP_002354869.1|3035780_3036335_-|septum-formation-protein-Maf
MQIILASQSPRRQELLKRVVPTFTIAPADIDETVGKDGLPAEYVAQMAAQKAAAIAEQSPEALVIGCDTIVALAGEILGKPTSREDGYRMLRLLSGKTHDVYTSVTLKQGEKERSATVHSTVTFYPLTDTEIHAYLDTAEYADKAGAYGIQGQGALLIEAIAGDYYAIMGLPIAKVARLLKEFN
>NC_004668.1|WP_002378991.1|3036359_3038492_-|DNA-mismatch-repair-endonuclease-MutL
MGKIQELSEQLANQIAAGEVVERPASVVKELVENALDAGSTQIDIFIEEAGLKTIQIIDNGEGIAKEDVLNAFKRHATSKIHTRDDLFRIRSLGFRGEALPSIASVSEMIVETATAEEEEGSYVILKGGKVEENRPAALRKGTKMTVSNLFYNTPARLKYVKTIQTELANIGDIVNRLALSHPKVAFRLVHDGHKMMSTTGNGDLKQTIAGIYGISTAKKMLKIEGKDLDFTLTGYVSLPEVTRASRNYLSTIINGRYIKNFALNKAIVAGYGSKLMVGRFPIAVLEIEMDPLLVDVNVHPTKQEVRLSKEKDLMALIEQAIQEVLSQEQLIPNAADNLRFKKKLPPEPKAEQMEIPLSTEQPAVKQRPGSLSYNPATGRFYAEHATDETPASSAPEAVNQTERAVDPMDDPFAPPVPESTSVAEETSAYETSSAAADSANHWETASNEQQVIAEETKITEVPDSEPSLRSSEAADEVFQEEMKLHPEFDANSAASQRELKQALNKLEEERPTERFPELEYFGQMHGTYLFAQSKDGLFIIDQHAAQERIKYEYFREKIGEVSDDLQELLVPIVIDYPNSDALKIKEQKETLAEVGIHLEDFGQNSFIVRAHPTWYPAGEEESIVREMIDMLLTTGSVSVKKFREATAIMMSCKRSIKANHYLNEQQARVLLKDLALCENPFNCPHGRPVLIHFTNSDMERMFKRIQDPH
>NC_004668.1|WP_002378992.1|3038523_3041100_-|DNA-mismatch-repair-protein-MutS
MPQKTKNTPMMEQYLSIKAQYKDAFLFYRLGDFYELFYEDAINAAQILELTLTSRNRNADDPIPMCGVPYHAAQGYIDTLIEQGYKVAICEQVEDPKTTKGMVKREVVQLVTPGTVMNSKGLEAKDNNYLTAVLTDGNQFGFAYVDLSTGELKTAVLADEEGVLNEASALQTKEMVLGSGIPESLKENLSLRLNIIFSTQETVEENAEFSFLTNELINPLEIEITGKLLSYLSVTQKRSLSHIQKAVEYQPDHFLKMDHYSKFNLELSQSIRTGQKKGTLLWLLDETKTAMGGRLLKQWLDRPLIQERQIKARQEMVQSLLNAYFERLDLQAALTNVYDLERLAGRVAFGSVNGRDLIQLRTSLEQVPTIRQLIVGINQGEWDDLLVDLNPVEDLVALIATAINEEAPLQITEGKVIKDGYNDQLDEYRDAMRNGKQWLAELEAKERQETGIKNLKIGYNRVFGYFIEITKSNLANLEEGKYERKQTLANAERFITPELKELERLILEAEEKSVELEYQLFLAVREQVKTNIDRLQTLAKTISAVDVLQSFATISERYQYVRPTLRSNTKNLAIVEGRHPVVEKVLGHQEYIPNSIRMNPETDILLITGPNMSGKSTYMRQLALTVVMAQIGCFVPAESAEMPIFDQIFTRIGASDDLIAGQSTFMVEMMEANQALRHATPNSLILFDELGRGTATYDGMALAQAIIEYIHREVQAKTLFSTHYHELTVLDETLKGLKNIHVGAVEKDGEVVFLHKMMEGPADKSYGIHVAKIAGLPSPLLERAATILSALEAEETTIPISVHHEEVSEVHEETEQLSLFKEVSTEELSVIDTLKKMNLLEMTPLDALNMLHQLQKRI
>NC_004668.1|WP_002354866.1|3041100_3041472_-|hypothetical-protein
MEPLNLDAQSNKELEKLLHLIGQDEVIQRYQAIEEKVKKNKKLTELVEEIKAAQKDAVQFAHYGKPTAEKEAIQRADAKTKEFDEHPLVVAYREQLIEANDLVQHVTALIQYRVNEELEKEGN
>NC_004668.1|WP_002354864.1|3041560_3042358_-|TIGR00282-family-metallophosphoesterase
MRILFIGDVVGSLGREALATYVPKLKKKYRPQVTIANGENAASGRGITGKIYKKFLQDGVDVVTMGNHTWDNKDIFEFIDDAKKMVRPANFPEDVPGQGMVFVKVNQLELAVINLQARTFMVPLEDPFKKAAELVAIARKRTPLIFVDFHGETTSEKQAMSWFLDGQVSAVVGTHTHVQTNDARILPKGTAFLSDVGMTGPYDGILGMKREPIIEKFMTALPKRFEVVETGRTILSACILEIDDQTGQAKMIEPIQISEDRPFQE
>NC_004668.1|WP_002354863.1|3042517_3044074_-|ribonuclease-Y
MVLNILLAIVGLIVGLGLGFVIAKSRHDKAINGAKISASSILENARKESETLKKEALLEAKEENQKYRSEIESELKESRLELKSQENRLIQREQTLDRKDDSLEKREGSLEEKEEKLGARQQLIDEREKEVENLINQQHQELERIASLSKEEAKSIIMKSTEEELNHELTLMVKESEQRAKEESDRKAKNLLSLAIQRCAADSVSETTVSVVTLPNDEMKGRIIGREGRNIRTLETLTGIDLIIDDTPEAVVLSGFDPIRREIARMTLEKLIQDGRIHPARIEEMVEKSRKEMDERIREYGEQAAFEVGAHTLHPDLIKILGRLRFRTSYGQNVLNHSIEVAKLAGVLAAELGEDVQLAKRAGLLHDIGKALDHEIEGSHVEIGAELAAKYKENSVVINAIASHHGDVEATSVISVLVAAADALSAARPGARSESLENYIRRLENLENISNSFEGVDSSFAVQAGREVRVMVKPEEISDLESVRLVRDIRKKIEDDLDYPGHIKVTVIRETRAVDYAK
>NC_004668.1|WP_002354860.1|3044470_3045517_-|recombinase-RecA
MADDRKVALDAALKKIEKNFGKGSIMKLGEKADQKISTIPSGSLALDVALGVGGYPRGRIIEVYGPESSGKTTVSLHAIAEVQRNGGTAAFIDAEHALDPQYAEKLGVNIDELLLSQPDTGEQGLEIADALVSSGAIDIVVIDSVAALVPRAEIDGEMGASHVGLQARLMSQALRKLSGSINKTKTIAIFINQIREKVGVMFGNPETTPGGRALKFYATVRLEVRRAEQLKQGTDIVGNRTKIKVVKNKVAPPFKVAEVDIMYGQGISQEGELLDMAVEKDLISKSGAWYGYKEERIGQGRENAKQYMADHPEMMAEVSKLVRDAYGIGDGSTITEEAEGQEELPLDE

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

289353 : 326185

Enterococcus_phage(97.92%)

capsid,head,integrase,holin,tail,portal

attL 288824:288838|attR 299795:299809

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
288824:288838	attL	NA	NA	NA	NA
WP_010714166.1\|289353_290568_-\|integrase	site-specific integrase	D2J023	Enterococcus_phage	2.1e-220	99.0
WP_010714167.1\|290723_291254_-	lipoprotein	D2J024	Enterococcus_phage	3.3e-85	98.9
WP_010714168.1\|291289_291967_-	ImmA/IrrE family metallo-endopeptidase	D2J025	Enterococcus_phage	5.4e-125	99.6
WP_002379958.1\|291986_292349_-	helix-turn-helix transcriptional regulator	D2J026	Enterococcus_phage	5.8e-57	100.0
WP_010714169.1\|292474_292687_+	helix-turn-helix transcriptional regulator	D2J027	Enterococcus_phage	1.9e-31	98.6
WP_002379960.1\|292765_293119_+	DUF1140 family protein	D2J028	Enterococcus_phage	4.9e-61	99.1
WP_002379961.1\|293124_293397_+	excisionase	D2J029	Enterococcus_phage	1.7e-45	100.0
WP_002407633.1\|293608_293809_+	hypothetical protein	D2J031	Enterococcus_phage	1.3e-31	98.5
WP_010714171.1\|293814_294033_+	aspartate decarboxylase	NA	NA	NA	NA
WP_010714172.1\|294029_294209_+	hypothetical protein	A0A0S2MY96	Enterococcus_phage	8.4e-17	76.8
WP_002399701.1\|294209_294404_+	hypothetical protein	D2J033	Enterococcus_phage	1.9e-27	96.9
WP_010773564.1\|294514_295204_+	DUF1642 domain-containing protein	D2J034	Enterococcus_phage	7.8e-79	64.9
WP_002399698.1\|295193_295442_+	hypothetical protein	NA	NA	NA	NA
WP_002399697.1\|295455_295608_+	hypothetical protein	D2J035	Enterococcus_phage	3.6e-21	100.0
WP_002399695.1\|295623_296103_+	hypothetical protein	D2J036	Enterococcus_phage	5.1e-45	86.8
WP_010714175.1\|296105_297278_+	DUF2800 domain-containing protein	D2J037	Enterococcus_phage	3.4e-223	99.5
WP_002399692.1\|297277_297526_+	2-hydroxyacyl-CoA dehydratase	D2J038	Enterococcus_phage	3.2e-35	97.5
WP_010714177.1\|297541_297871_+	hypothetical protein	D2J039	Enterococcus_phage	1.2e-53	98.2
WP_002399690.1\|297897_298473_+	DUF2815 family protein	D2J040	Enterococcus_phage	2.1e-101	99.0
WP_010714178.1\|298525_298747_+	hypothetical protein	D2J041	Enterococcus_phage	9.7e-15	59.5
WP_010714179.1\|298733_299282_+	hypothetical protein	D2J042	Enterococcus_phage	3.5e-90	95.6
WP_002399687.1\|299278_301240_+	DNA polymerase	D2J043	Enterococcus_phage	0.0e+00	99.5
299795:299809	attR	NA	NA	NA	NA
WP_002399686.1\|301252_301492_+	hypothetical protein	A0A0E3T926	Enterococcus_phage	5.4e-11	46.6
WP_002399685.1\|301510_301813_+	hypothetical protein	A0A1W6JHU2	Lactococcus_phage	2.6e-10	32.7
WP_010714181.1\|302014_304453_+	hypothetical protein	D2J048	Enterococcus_phage	0.0e+00	97.5
WP_010714182.1\|304825_305146_+	VRR-NUC domain-containing protein	D2J049	Enterococcus_phage	2.2e-52	95.3
WP_010714183.1\|305152_306526_+	DEAD/DEAH box helicase	D2J050	Enterococcus_phage	3.2e-265	99.3
WP_010714330.1\|306669_307140_+	hypothetical protein	D2J051	Enterococcus_phage	3.8e-61	80.1
WP_010714185.1\|307230_307680_+	hypothetical protein	D2IZL8	Enterococcus_phage	8.2e-69	83.9
WP_010714186.1\|307676_308933_+	hypothetical protein	D2J053	Enterococcus_phage	1.7e-233	96.7
WP_010714187.1\|308947_310480_+\|portal	phage portal protein	D2J056	Enterococcus_phage	3.4e-284	97.6
WP_011109439.1\|310409_311873_+	NAD+--arginine ADP-ribosyltransferase EFV	D2J057	Enterococcus_phage	2.6e-164	97.7
WP_010714189.1\|311865_312069_+	hypothetical protein	NA	NA	NA	NA
WP_010714190.1\|312126_312336_+	hypothetical protein	D2J059	Enterococcus_phage	6.3e-24	63.6
WP_002403766.1\|312472_313045_+	scaffold protein	D2J060	Enterococcus_phage	5.5e-94	99.5
WP_010714191.1\|313060_313924_+\|capsid	phage capsid protein	D2J061	Enterococcus_phage	6.9e-157	99.7
WP_010714192.1\|314226_314760_+	hypothetical protein	D2J063	Enterococcus_phage	1.3e-92	98.3
WP_002392896.1\|314759_315098_+\|head,tail	head-tail adaptor protein	D2J064	Enterococcus_phage	1.0e-60	100.0
WP_002403769.1\|315084_315516_+	HK97 gp10 family phage protein	D2J065	Enterococcus_phage	7.8e-77	100.0
WP_010714193.1\|315519_315903_+	hypothetical protein	D2J066	Enterococcus_phage	5.0e-67	99.2
WP_010714194.1\|315889_316516_+	hypothetical protein	D2J067	Enterococcus_phage	9.5e-108	98.5
WP_010714195.1\|316618_317059_+	hypothetical protein	D2J068	Enterococcus_phage	1.7e-66	94.5
WP_010714196.1\|317148_317373_+	hypothetical protein	D2J069	Enterococcus_phage	2.0e-31	97.3
WP_010714197.1\|317372_320522_+\|tail	tail protein	D2J070	Enterococcus_phage	3.6e-272	86.8
WP_010714198.1\|320534_321410_+\|tail	phage tail family protein	D2J071	Enterococcus_phage	3.6e-161	96.2
WP_010714199.1\|321409_322495_+	hypothetical protein	D2J072	Enterococcus_phage	1.1e-188	92.0
WP_010714200.1\|322505_323540_+	structural protein	D2J073	Enterococcus_phage	9.3e-92	56.0
WP_002405480.1\|323550_324342_+	hypothetical protein	D2J018	Enterococcus_phage	8.8e-34	84.0
WP_002379918.1\|324417_324672_+\|holin	holin	D2J075	Enterococcus_phage	8.5e-39	100.0
WP_002379919.1\|324674_324881_+\|holin	holin	A0A0S2MYF6	Enterococcus_phage	7.6e-30	98.5
WP_010774154.1\|324883_326185_+	LysM peptidoglycan-binding domain-containing protein	D2J077	Enterococcus_phage	2.3e-233	97.0

DBSCAN-SWA_2

877235 : 885149

Planktothrix_phage(16.67%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_002364714.1\|877235_878288_+	ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	2.0e-17	30.1
WP_002355795.1\|878287_879244_+	ATP-binding cassette domain-containing protein	A0A1J0FA64	Only_Syngen_Nebraska_virus	3.2e-06	23.9
WP_002355796.1\|879284_880355_+	helix-turn-helix domain-containing protein	A0A288TXV8	Enterococcus_phage	7.6e-89	49.0
WP_002355797.1\|880754_881276_+	translation initiation factor IF-3	A0A2L0UZ54	Agrobacterium_phage	3.0e-14	33.3
WP_002355798.1\|881389_881590_+	50S ribosomal protein L35	NA	NA	NA	NA
WP_002355799.1\|881650_882010_+	50S ribosomal protein L20	NA	NA	NA	NA
WP_002385048.1\|882055_882436_-	hypothetical protein	NA	NA	NA	NA
WP_002361363.1\|882503_882863_+	DUF1304 domain-containing protein	NA	NA	NA	NA
WP_025187394.1\|882930_883425_+	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_002379186.1\|883442_883958_+	GrpB family protein	A0A2K5B2B6	Erysipelothrix_phage	1.0e-38	48.8
WP_002380126.1\|883973_885149_-	SulP family inorganic anion transporter	A0A2H4J153	uncultured_Caudovirales_phage	3.3e-85	47.7

DBSCAN-SWA_3

1242192 : 1259965

Enterococcus_phage(46.15%)

tail,holin

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_002357859.1\|1242192_1244589_+	translation initiation factor IF-2	A0A2H4UTS4	Bodo_saltans_virus	1.7e-19	24.1
WP_002360497.1\|1244613_1244964_+	30S ribosome-binding factor RbfA	NA	NA	NA	NA
WP_002382231.1\|1245046_1245277_+	hypothetical protein	NA	NA	NA	NA
WP_002382232.1\|1245336_1245822_-	toxin	A0A097BY56	Enterococcus_phage	4.4e-60	70.5
WP_002360496.1\|1245856_1246339_-	helix-turn-helix domain-containing protein	R9QTP6	Staphylococcus_phage	2.6e-20	47.7
WP_002382234.1\|1246736_1247492_+	DnaD domain protein	A0A0K0MX39	Streptococcus_phage	6.7e-31	56.0
WP_002382235.1\|1247510_1248353_+	ATP-binding protein	A0A0P0I3L9	Lactobacillus_phage	4.4e-31	31.0
WP_002360492.1\|1248419_1248812_+	hypothetical protein	NA	NA	NA	NA
WP_002379371.1\|1248831_1249239_+	RinA family phage transcriptional activator	NA	NA	NA	NA
WP_002382237.1\|1249460_1249877_+	hypothetical protein	NA	NA	NA	NA
WP_002365550.1\|1249889_1250402_+\|tail	phage major tail protein, TP901-1 family	W6LP72	Streptococcus_phage	8.8e-35	49.4
WP_002357848.1\|1250434_1250794_+	hypothetical protein	A0A0F6N4J9	Staphylococcus_phage	7.6e-09	32.2
WP_002382238.1\|1250886_1251180_+	hypothetical protein	NA	NA	NA	NA
WP_002382239.1\|1251169_1254103_+	membrane protein	A0A1U9WR55	Streptococcus_virus	6.6e-10	25.3
WP_002382240.1\|1254104_1255031_+\|tail	phage tail family protein	C9E2K5	Enterococcus_phage	3.4e-146	78.2
WP_002379375.1\|1255043_1256501_+	hypothetical protein	C9E2K6	Enterococcus_phage	5.5e-175	47.7
WP_002379376.1\|1256533_1258303_+	hypothetical protein	A0A097BYA8	Enterococcus_phage	1.5e-142	71.6
WP_002357842.1\|1258326_1258722_+\|holin	phage holin family protein	F0PIJ6	Enterococcus_phage	2.8e-33	48.9
WP_002382241.1\|1258840_1259965_+	N-acetylmuramoyl-L-alanine amidase	A0A139ZVY1	Enterococcus_phage	3.2e-77	44.3

DBSCAN-SWA_4

1398096 : 1443843

Listeria_phage(47.73%)

plate,head,integrase,terminase,tail

attL 1398051:1398073|attR 1446151:1446173

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
1398051:1398073	attL	NA	NA	NA	NA
WP_010774185.1\|1398096_1399323_-\|integrase	site-specific integrase	A0A0P0I3D2	Lactobacillus_phage	6.5e-76	41.9
WP_010774186.1\|1399322_1399604_-	hypothetical protein	NA	NA	NA	NA
WP_010774187.1\|1399759_1400353_-	hypothetical protein	D2J022	Enterococcus_phage	1.1e-23	55.3
WP_010774188.1\|1400411_1401164_-	DUF4950 domain-containing protein	C9E2L5	Enterococcus_phage	5.7e-06	35.6
WP_010774189.1\|1401181_1401646_-	ImmA/IrrE family metallo-endopeptidase	R4IBK9	Listeria_phage	9.5e-20	35.8
WP_010774190.1\|1401666_1401990_-	helix-turn-helix transcriptional regulator	A8ATJ9	Listeria_phage	2.3e-17	66.7
WP_010774191.1\|1402155_1402341_+	helix-turn-helix transcriptional regulator	A8ATK0	Listeria_phage	2.1e-10	58.6
WP_050563765.1\|1402353_1402533_+	hypothetical protein	NA	NA	NA	NA
WP_025188979.1\|1402601_1403156_+	hypothetical protein	NA	NA	NA	NA
WP_002386711.1\|1403205_1403367_+	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_002392050.1\|1403378_1403546_+	hypothetical protein	NA	NA	NA	NA
WP_010774193.1\|1403546_1403762_+	hypothetical protein	NA	NA	NA	NA
WP_002392047.1\|1403817_1404108_+	hypothetical protein	NA	NA	NA	NA
WP_010774194.1\|1404112_1406236_+	AAA family ATPase	A0A1L2K2K3	Aeribacillus_phage	1.9e-51	26.3
WP_010774195.1\|1406236_1406491_+	hypothetical protein	NA	NA	NA	NA
WP_010774196.1\|1406480_1407668_+	hypothetical protein	NA	NA	NA	NA
WP_002390536.1\|1407667_1408369_+	MBL fold metallo-hydrolase	A0A1L2JY21	Aeribacillus_phage	6.0e-50	42.7
WP_002386717.1\|1408380_1409145_+	DnaD domain protein	A0A1B0Y2R2	Lactobacillus_phage	7.5e-14	61.4
WP_010774197.1\|1409160_1409658_+	recombination protein U	A0A1L2JY30	Aeribacillus_phage	1.2e-12	34.8
WP_002390537.1\|1409678_1409993_+	hypothetical protein	NA	NA	NA	NA
WP_002390538.1\|1410076_1410826_+	hypothetical protein	D2IZY3	Enterococcus_phage	6.7e-116	84.1
WP_002390542.1\|1410850_1411078_+	hypothetical protein	C9E2N4	Enterococcus_phage	6.2e-33	92.0
WP_002390543.1\|1411098_1411326_+	hypothetical protein	NA	NA	NA	NA
WP_010774198.1\|1411331_1411757_+	hypothetical protein	A0A097BY34	Enterococcus_phage	1.9e-35	56.2
WP_002399989.1\|1411740_1412178_+	hypothetical protein	D2IZL0	Enterococcus_phage	1.2e-13	38.4
WP_002399990.1\|1412178_1412517_+	hypothetical protein	A8E2L3	Enterococcus_phage	2.2e-26	77.8
WP_002399991.1\|1412513_1412867_+	DNA topoisomerase	NA	NA	NA	NA
WP_002399992.1\|1412863_1413451_+	DUF1642 domain-containing protein	D2IZL3	Enterococcus_phage	1.0e-55	60.0
WP_002399993.1\|1413447_1413933_+	hypothetical protein	C9E2P0	Enterococcus_phage	3.4e-89	98.1
WP_002399994.1\|1413933_1414251_+	replicase	NA	NA	NA	NA
WP_002399995.1\|1414244_1414451_+	hypothetical protein	D2IZL5	Enterococcus_phage	1.2e-27	86.4
WP_002377565.1\|1414451_1414631_+	hypothetical protein	NA	NA	NA	NA
WP_002377564.1\|1414762_1414951_+	hypothetical protein	NA	NA	NA	NA
WP_010774200.1\|1415051_1415636_+	positive control factor	NA	NA	NA	NA
WP_002399996.1\|1416342_1416645_+	hypothetical protein	NA	NA	NA	NA
WP_010774201.1\|1416689_1417958_+	DNA modification methylase	A0A2I4R670	Erysipelothrix_phage	1.2e-96	47.1
WP_002386742.1\|1418083_1418314_+	hypothetical protein	A8ATN7	Listeria_phage	8.0e-12	53.8
WP_002399998.1\|1418328_1419054_+\|terminase	terminase small subunit	A0A1W6JNJ8	Staphylococcus_phage	4.2e-06	32.4
WP_002399999.1\|1419034_1420471_+\|terminase	phage terminase large subunit	A5GYP8	Lactococcus_phage	3.5e-198	71.3
WP_002400000.1\|1420493_1421888_+	DUF1073 domain-containing protein	A8ATG1	Listeria_phage	4.0e-146	56.4
WP_002400001.1\|1421850_1423122_+\|head	phage head morphogenesis protein	A8ATG2	Listeria_phage	1.4e-52	41.6
WP_002390571.1\|1423114_1423279_+	hypothetical protein	NA	NA	NA	NA
WP_002386748.1\|1423335_1423623_+	hypothetical protein	A0A0S2MYE7	Enterococcus_phage	1.7e-27	68.3
WP_010774203.1\|1423615_1423825_+	LysM peptidoglycan-binding domain-containing protein	NA	NA	NA	NA
WP_010774204.1\|1423837_1424938_+	DUF2213 domain-containing protein	A8ATG4	Listeria_phage	2.5e-87	58.6
WP_002386751.1\|1424940_1425411_+	hypothetical protein	NA	NA	NA	NA
WP_010733792.1\|1425431_1426313_+	DUF2184 domain-containing protein	A8ATG6	Listeria_phage	6.7e-83	52.2
WP_010774205.1\|1426332_1426719_+	hypothetical protein	NA	NA	NA	NA
WP_002377536.1\|1426730_1427072_+	DUF4054 domain-containing protein	NA	NA	NA	NA
WP_010774206.1\|1427071_1427674_+	hypothetical protein	A8ATG9	Listeria_phage	7.2e-36	44.6
WP_002400009.1\|1427673_1428033_+	hypothetical protein	A0A2H4JDP3	uncultured_Caudovirales_phage	2.3e-13	43.7
WP_010717320.1\|1428019_1428496_+	hypothetical protein	A8ATH1	Listeria_phage	5.5e-23	42.8
WP_010717321.1\|1428492_1429530_+	DUF3383 family protein	A8ATH2	Listeria_phage	6.4e-101	56.4
WP_002377526.1\|1429545_1429944_+	hypothetical protein	A8ATH3	Listeria_phage	6.6e-30	54.0
WP_002386763.1\|1429996_1430329_+	hypothetical protein	A8ATH4	Listeria_phage	1.8e-25	56.9
WP_165439037.1\|1430369_1430510_+	hypothetical protein	A8ATH5	Listeria_phage	6.8e-06	67.6
WP_010774207.1\|1430512_1435678_+	peptidoglycan DD-metalloendopeptidase family protein	A8ATH6	Listeria_phage	1.6e-152	37.0
WP_002386767.1\|1435677_1436235_+	LysM peptidoglycan-binding domain-containing protein	A8ATH7	Listeria_phage	2.8e-34	43.2
WP_002377517.1\|1436244_1436607_+	hypothetical protein	A8ATH8	Listeria_phage	5.1e-29	46.6
WP_002390593.1\|1436607_1437438_+	hypothetical protein	A8ATH9	Listeria_phage	7.8e-65	45.8
WP_002377515.1\|1437437_1437770_+	hypothetical protein	A8ATI0	Listeria_phage	1.6e-21	50.0
WP_002390594.1\|1437769_1438117_+	DUF2634 domain-containing protein	A0A2H4J4S8	uncultured_Caudovirales_phage	2.9e-13	49.4
WP_002390596.1\|1438109_1439264_+\|plate	baseplate J/gp47 family protein	A8ATI2	Listeria_phage	1.3e-113	54.1
WP_002390597.1\|1439247_1439877_+	hypothetical protein	A8ATI3	Listeria_phage	3.1e-58	57.4
WP_002390599.1\|1439889_1441539_+\|tail	tail fiber protein	D2J018	Enterococcus_phage	7.6e-112	66.7
WP_002390600.1\|1441560_1441995_+	hypothetical protein	NA	NA	NA	NA
WP_002377507.1\|1441994_1442123_+	XkdX family protein	NA	NA	NA	NA
WP_002377506.1\|1442127_1442484_+	hypothetical protein	NA	NA	NA	NA
WP_002390601.1\|1442480_1442678_+	hypothetical protein	NA	NA	NA	NA
WP_002390604.1\|1442736_1443843_+	N-acetylmuramoyl-L-alanine amidase	V5URN7	Enterococcus_phage	6.2e-86	48.0
1446151:1446173	attR	NA	NA	NA	NA

DBSCAN-SWA_5

1723243 : 1731887

Synechococcus_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_002369276.1\|1723243_1723816_-	phosphoribosylglycinamide formyltransferase	M4QRX9	Synechococcus_phage	4.1e-25	35.1
WP_002369275.1\|1723812_1724844_-	phosphoribosylformylglycinamidine cyclo-ligase	A0A0E3FGG1	Synechococcus_phage	8.2e-56	44.4
WP_002382407.1\|1724845_1726285_-	amidophosphoribosyltransferase	A0A0M3SGR2	Mollivirus	2.1e-49	33.0
WP_002369272.1\|1726260_1728480_-	phosphoribosylformylglycinamidine synthase subunit PurL	A6N228	Microbacterium_phage	9.7e-147	39.9
WP_002369271.1\|1728476_1729151_-	phosphoribosylformylglycinamidine synthase subunit PurQ	NA	NA	NA	NA
WP_002357271.1\|1729151_1729403_-	phosphoribosylformylglycinamidine synthase subunit PurS	NA	NA	NA	NA
WP_002369269.1\|1729416_1730130_-	phosphoribosylaminoimidazolesuccinocarboxamide synthase	A0A0E3ELR0	Synechococcus_phage	5.7e-48	43.0
WP_002379523.1\|1730281_1731406_-	5-(carboxyamino)imidazole ribonucleotide synthase	NA	NA	NA	NA
WP_002365766.1\|1731398_1731887_-	5-(carboxyamino)imidazole ribonucleotide mutase	A0A2P0VNU7	Tetraselmis_virus	6.4e-19	42.0

DBSCAN-SWA_6

1762057 : 1804051

Clostridium_botulinum_C_phage(16.67%)

protease,transposase,integrase

attL 1802249:1802273|attR 1807314:1807338

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_002386892.1\|1762057_1762936_-\|protease	trypsin-like serine protease	NA	NA	NA	NA
WP_002369251.1\|1762960_1764493_-	M4 family metallopeptidase coccolysin	NA	NA	NA	NA
WP_002386893.1\|1764727_1766071_-	GHKL domain-containing protein	NA	NA	NA	NA
WP_002369249.1\|1766067_1766796_-	accessory gene regulator AgrB	NA	NA	NA	NA
WP_002369247.1\|1766884_1767628_-	response regulator transcription factor	NA	NA	NA	NA
WP_002382428.1\|1768034_1769993_-	amidase domain-containing protein	Q332B8	Clostridium_botulinum_C_phage	1.4e-19	37.4
WP_002382429.1\|1770074_1775702_-	DUF5110 domain-containing protein	NA	NA	NA	NA
WP_002369244.1\|1776205_1776601_-	hypothetical protein	NA	NA	NA	NA
WP_002382430.1\|1776648_1777698_-	alcohol dehydrogenase AdhP	A0A2K9L339	Tupanvirus	3.1e-26	25.3
WP_002369243.1\|1778179_1779160_+	nickel pincer cofactor biosynthesis protein LarC	NA	NA	NA	NA
WP_002357197.1\|1779174_1779885_+	aquaporin family protein	NA	NA	NA	NA
WP_002357196.1\|1780088_1780931_-	PTS system mannose/fructose/sorbose family transporter subunit IID	NA	NA	NA	NA
WP_002357194.1\|1780932_1781784_-	PTS sugar transporter subunit IIC	NA	NA	NA	NA
WP_002357192.1\|1781817_1782315_-	PTS transporter subunit IIB	NA	NA	NA	NA
WP_002369242.1\|1782329_1782761_-	PTS fructose transporter subunit IIA	NA	NA	NA	NA
WP_002369241.1\|1783341_1783629_+	hypothetical protein	NA	NA	NA	NA
WP_002369240.1\|1783874_1784390_-	galactose-6-phosphate isomerase subunit LacB	NA	NA	NA	NA
WP_002357188.1\|1784415_1784844_-	galactose-6-phosphate isomerase subunit LacA	NA	NA	NA	NA
WP_002357187.1\|1785066_1785561_+	PTS sugar transporter subunit IIA	NA	NA	NA	NA
WP_002357185.1\|1785562_1785865_+	PTS fructose transporter subunit IIB	NA	NA	NA	NA
WP_002357183.1\|1785959_1787363_+	PTS glucitol transporter subunit IIA	NA	NA	NA	NA
WP_002369238.1\|1787403_1788156_-	DeoR/GlpR transcriptional regulator	NA	NA	NA	NA
WP_002369236.1\|1788491_1789337_-	DUF4767 domain-containing protein	NA	NA	NA	NA
WP_002390435.1\|1789572_1790151_-	HD domain-containing protein	NA	NA	NA	NA
WP_002369233.1\|1790374_1791280_+	polysaccharide deacetylase	NA	NA	NA	NA
WP_002360100.1\|1791453_1791870_-	hypothetical protein	NA	NA	NA	NA
WP_002297659.1\|1793027_1794206_-\|integrase	site-specific integrase	S6C485	Thermus_phage	3.4e-29	30.5
WP_002297662.1\|1794308_1794620_-	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_002360096.1\|1794968_1795214_-	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_002297668.1\|1795207_1795609_-	sigma-70 family RNA polymerase sigma factor	NA	NA	NA	NA
WP_002369229.1\|1796176_1798012_-	beta-galactosidase	NA	NA	NA	NA
WP_002330923.1\|1798183_1799446_-	PTS sugar transporter subunit IIC	NA	NA	NA	NA
WP_002360092.1\|1799583_1799808_+	hypothetical protein	NA	NA	NA	NA
WP_002298159.1\|1799804_1799969_+	hypothetical protein	NA	NA	NA	NA
WP_002298157.1\|1800062_1801355_-\|transposase	IS256 family transposase	A0A218MNI5	uncultured_virus	3.9e-31	40.4
WP_002313174.1\|1801628_1801889_-	hypothetical protein	NA	NA	NA	NA
1802249:1802273	attL	NA	NA	NA	NA
WP_099704284.1\|1802493_1803655_+\|transposase	IS3 family transposase	A0A2I7SC85	Paenibacillus_phage	2.0e-79	51.3
WP_077497620.1\|1803727_1803934_+\|integrase,transposase	DDE-type integrase/transposase/recombinase	U5P429	Shigella_phage	2.0e-06	53.3
WP_002383094.1\|1803937_1804051_+\|transposase	IS3 family transposase	NA	NA	NA	NA
1807314:1807338	attR	NA	NA	NA	NA

DBSCAN-SWA_7

1821780 : 1832263

Streptococcus_phage(100.0%)

transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_002330911.1\|1821780_1823904_-\|transposase	transposase	A0A1S5SF30	Streptococcus_phage	6.2e-175	58.7
WP_002330910.1\|1823908_1826356_-	ATP-binding protein	A0A1S5SF64	Streptococcus_phage	0.0e+00	76.4
WP_002298826.1\|1826342_1826732_-	conjugal transfer protein	A0A1S5SEX7	Streptococcus_phage	2.5e-42	66.7
WP_002383098.1\|1826783_1827524_+	hypothetical protein	NA	NA	NA	NA
WP_002360078.1\|1827530_1828367_-	abortive infection family protein	NA	NA	NA	NA
WP_002369218.1\|1828431_1828935_-	antirestriction protein ArdA	A0A1S5SF25	Streptococcus_phage	1.2e-55	60.6
WP_002298822.1\|1828947_1829169_-	hypothetical protein	A0A1S5SEY0	Streptococcus_phage	4.5e-28	87.7
WP_002346915.1\|1829565_1830816_+\|transposase	IS110 family transposase	M1NSC9	Streptococcus_phage	6.1e-114	62.1
WP_002330905.1\|1830947_1831082_-	DUF3789 domain-containing protein	NA	NA	NA	NA
WP_002360076.1\|1831078_1832263_-	XRE family transcriptional regulator	A0A1S5SEX3	Streptococcus_phage	1.0e-142	62.1

DBSCAN-SWA_8

1907074 : 1947660

Enterococcus_phage(26.67%)

head,terminase,holin,tail,tRNA,portal

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_002379571.1\|1907074_1908844_-\|tRNA	aspartate--tRNA ligase	A0A2K9L424	Tupanvirus	3.0e-13	30.3
WP_002366882.1\|1908861_1910163_-\|tRNA	histidine--tRNA ligase	A0A2I2L577	Orpheovirus	8.8e-23	26.8
WP_002383130.1\|1910159_1910381_-	hypothetical protein	NA	NA	NA	NA
WP_002357080.1\|1910520_1910967_-\|tRNA	D-tyrosyl-tRNA(Tyr) deacylase	NA	NA	NA	NA
WP_002357079.1\|1910990_1913204_-	bifunctional (p)ppGpp synthetase/guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase	A0A2I2L310	Orpheovirus	1.3e-10	38.0
WP_002370972.1\|1913418_1914171_-	16S rRNA (uracil(1498)-N(3))-methyltransferase	NA	NA	NA	NA
WP_011109511.1\|1914172_1915120_-	50S ribosomal protein L11 methyltransferase	NA	NA	NA	NA
WP_002383131.1\|1915135_1915630_-	DUF3013 family protein	NA	NA	NA	NA
WP_002364174.1\|1915577_1916255_-	DNA-3-methyladenine glycosylase	NA	NA	NA	NA
WP_011109512.1\|1916383_1917661_+	replication-associated recombination protein A	A0A127AWE7	Bacillus_phage	2.4e-105	49.9
WP_002357068.1\|1917934_1918267_+	hypothetical protein	NA	NA	NA	NA
WP_002383133.1\|1918551_1919058_+	universal stress protein	NA	NA	NA	NA
WP_002357064.1\|1919169_1920357_-	acetate kinase	NA	NA	NA	NA
WP_025192526.1\|1920381_1920603_-	hypothetical protein	NA	NA	NA	NA
WP_010774221.1\|1920603_1921389_-	class I SAM-dependent methyltransferase	NA	NA	NA	NA
WP_002357061.1\|1921517_1921871_-	hypothetical protein	NA	NA	NA	NA
WP_002357060.1\|1921870_1922305_-	ComGF family competence protein	NA	NA	NA	NA
WP_002393943.1\|1922294_1922621_-	type II secretion system protein	NA	NA	NA	NA
WP_002364185.1\|1923421_1924363_-	ferrochelatase	NA	NA	NA	NA
WP_002383136.1\|1925102_1925351_-	hypothetical protein	NA	NA	NA	NA
WP_002357053.1\|1925422_1925623_-	cold-shock protein	Q9AZD3	Lactococcus_phage	1.6e-24	80.3
WP_002370962.1\|1926459_1927701_-	LysM peptidoglycan-binding domain-containing protein	A0A0S2MYF3	Enterococcus_phage	6.6e-169	71.7
WP_002384371.1\|1927701_1927935_-\|holin	phage holin	D2J020	Enterococcus_phage	1.9e-29	87.8
WP_002364191.1\|1927927_1928149_-	hypothetical protein	D2J019	Enterococcus_phage	2.5e-31	93.2
WP_002364192.1\|1928183_1928339_-	XkdX family protein	A0A1W6JQ64	Staphylococcus_phage	7.2e-09	55.6
WP_002383141.1\|1928340_1928685_-	hypothetical protein	NA	NA	NA	NA
WP_002364194.1\|1928674_1929166_-	hypothetical protein	NA	NA	NA	NA
WP_002357046.1\|1929165_1929453_-	collagen-like protein	NA	NA	NA	NA
WP_002357045.1\|1929449_1930046_-	hypothetical protein	NA	NA	NA	NA
WP_002387289.1\|1930939_1933747_-	CHAP domain-containing protein	Q9AZX5	Lactococcus_phage	1.5e-144	38.6
WP_011109514.1\|1933728_1934463_-\|tail	tail protein	NA	NA	NA	NA
WP_002387288.1\|1934452_1937350_-	tape measure protein	D7RWD8	Brochothrix_phage	5.4e-81	46.4
WP_002357039.1\|1937597_1937948_-	hypothetical protein	A0A2H4JAA8	uncultured_Caudovirales_phage	2.9e-05	33.3
WP_002387287.1\|1938000_1938849_-\|tail	tail protein	A0A288TYF3	Enterococcus_phage	3.2e-05	42.5
WP_002387286.1\|1938849_1939224_-	hypothetical protein	NA	NA	NA	NA
WP_002357036.1\|1939226_1939625_-	HK97 gp10 family phage protein	NA	NA	NA	NA
WP_002387285.1\|1939617_1939992_-	hypothetical protein	NA	NA	NA	NA
WP_002387282.1\|1939988_1940333_-	hypothetical protein	NA	NA	NA	NA
WP_002387281.1\|1940346_1940529_-	hypothetical protein	NA	NA	NA	NA
WP_002387280.1\|1940557_1941445_-	DUF5309 domain-containing protein	NA	NA	NA	NA
WP_010706493.1\|1941458_1942082_-	DUF4355 domain-containing protein	NA	NA	NA	NA
WP_002380436.1\|1942300_1942621_-	hypothetical protein	NA	NA	NA	NA
WP_002380437.1\|1942677_1942908_-	hypothetical protein	NA	NA	NA	NA
WP_010706494.1\|1942908_1944813_-\|head	head protein	NA	NA	NA	NA
WP_010706495.1\|1944787_1946260_-\|portal	phage portal protein	A0A0A7AQF2	Bacillus_phage	1.2e-31	26.7
WP_002387276.1\|1946271_1947660_-\|terminase	phage terminase large subunit	Q9AZ66	Lactococcus_phage	2.8e-176	67.4

DBSCAN-SWA_9

1954154 : 1962485

Lactobacillus_phage(25.0%)

integrase

attL 1950617:1950631|attR 1972673:1972687

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
1950617:1950631	attL	NA	NA	NA	NA
WP_002387271.1\|1954154_1955012_-	helix-turn-helix domain-containing protein	A0A0P0ICZ8	Lactobacillus_phage	1.8e-24	36.1
WP_002357010.1\|1955011_1955212_-	hypothetical protein	NA	NA	NA	NA
WP_002383799.1\|1955861_1956596_-	ERF family protein	A0A1W6JNQ5	Staphylococcus_phage	3.0e-20	29.9
WP_002383798.1\|1956588_1956906_-	hypothetical protein	NA	NA	NA	NA
WP_002383796.1\|1957101_1957440_-	hypothetical protein	NA	NA	NA	NA
WP_002378465.1\|1957476_1957686_-	hypothetical protein	D2IZ57	Enterococcus_phage	8.8e-18	74.2
WP_002357001.1\|1957740_1957929_+	YegP family protein	NA	NA	NA	NA
WP_002387270.1\|1957954_1958677_-	phage regulatory protein	D2IYT0	Enterococcus_phage	5.6e-43	46.5
WP_002403885.1\|1958699_1959011_-	hypothetical protein	NA	NA	NA	NA
WP_002383936.1\|1959022_1959214_-	hypothetical protein	NA	NA	NA	NA
WP_002387267.1\|1959509_1959851_+	helix-turn-helix transcriptional regulator	A0A1P8BMG3	Lactococcus_phage	3.2e-17	46.8
WP_002387266.1\|1959855_1960506_+	ImmA/IrrE family metallo-endopeptidase	S4U0J6	uncultured_phage	9.2e-13	29.9
WP_002387265.1\|1960601_1961231_+	SHOCT domain-containing protein	O48432	Lactobacillus_phage	2.7e-09	33.6
WP_002387264.1\|1961336_1962485_+\|integrase	site-specific integrase	A0A1C8E994	Bacillus_phage	1.1e-37	29.9
1972673:1972687	attR	NA	NA	NA	NA

DBSCAN-SWA_10

2002277 : 2020730

Enterococcus_phage(44.44%)

holin

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_002356948.1\|2002277_2003348_-	methionine ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	4.0e-29	35.1
WP_002359996.1\|2004909_2005158_+	hypothetical protein	A0A097BYB1	Enterococcus_phage	6.1e-34	91.5
WP_002359995.1\|2005176_2006145_-	Abi family protein	A0A059NT88	Lactococcus_phage	1.3e-79	43.5
WP_002399567.1\|2006955_2007957_-	endolysin	F0PIJ7	Enterococcus_phage	1.9e-86	68.4
WP_002359993.1\|2007928_2008207_-\|holin	holin	NA	NA	NA	NA
WP_002359992.1\|2008206_2008461_-	hypothetical protein	NA	NA	NA	NA
WP_002359991.1\|2008473_2008893_-	XkdX family protein	F0PIJ5	Enterococcus_phage	1.1e-56	85.4
WP_002399568.1\|2008880_2009741_-	collagen-like protein	F0PIJ4	Enterococcus_phage	1.2e-60	87.3
WP_002359989.1\|2009727_2010216_-	hypothetical protein	A0A1W6JI16	Lactococcus_phage	8.4e-35	46.0
WP_002359987.1\|2010228_2010921_-	hypothetical protein	NA	NA	NA	NA
WP_002359986.1\|2010917_2013494_-	endolysin	A0A1B1IM47	Lactococcus_phage	1.3e-30	46.6
WP_002359985.1\|2013530_2014442_-	hypothetical protein	NA	NA	NA	NA
WP_002399570.1\|2014447_2015563_-	hypothetical protein	NA	NA	NA	NA
WP_002399571.1\|2015567_2020730_-	tape measure protein	A0A1P8VVL4	Streptococcus_phage	1.5e-41	30.2

DBSCAN-SWA_11

2031762 : 2045460

Enterococcus_phage(52.94%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_002393641.1\|2031762_2032182_-	hypothetical protein	A0A2H4J1L3	uncultured_Caudovirales_phage	1.0e-17	50.0
WP_002399577.1\|2032171_2033374_-	ParB N-terminal domain-containing protein	Q708N6	Streptococcus_phage	3.9e-110	50.8
WP_002359961.1\|2033781_2034207_-	ArpU family transcriptional regulator	D2IYV6	Enterococcus_phage	7.6e-24	42.3
WP_002359960.1\|2034505_2034706_-	hypothetical protein	D2IYV2	Enterococcus_phage	1.6e-24	83.3
WP_002399578.1\|2034719_2035274_-	DUF3850 domain-containing protein	C9E2N9	Enterococcus_phage	5.7e-48	55.1
WP_002399580.1\|2035758_2036301_-	hypothetical protein	A0A0S2MYC7	Enterococcus_phage	4.6e-42	95.7
WP_002399581.1\|2036325_2036550_-	hypothetical protein	NA	NA	NA	NA
WP_002399583.1\|2036639_2036852_-	hypothetical protein	NA	NA	NA	NA
WP_011109521.1\|2036929_2037412_-	class I SAM-dependent methyltransferase	D2IYU6	Enterococcus_phage	4.8e-83	90.3
WP_021733001.1\|2037558_2037702_-	hypothetical protein	D2IYU4	Enterococcus_phage	7.4e-16	95.7
WP_002399586.1\|2037718_2038078_-	hypothetical protein	A0A2L0V129	Agrobacterium_phage	1.1e-12	41.6
WP_002399587.1\|2038080_2038413_-	hypothetical protein	A0A0S2MYB8	Enterococcus_phage	2.1e-21	58.4
WP_010774223.1\|2038409_2038835_-	RusA family crossover junction endodeoxyribonuclease	D2IYU2	Enterococcus_phage	6.1e-58	79.7
WP_002399589.1\|2038843_2039713_-	ATP-binding protein	U5PWH5	Bacillus_phage	6.1e-20	29.1
WP_010714058.1\|2039726_2040578_-	DUF4373 domain-containing protein	D2IZY0	Enterococcus_phage	1.7e-46	45.1
WP_002399591.1\|2040591_2041410_-	hypothetical protein	J7KGZ1	Streptococcus_phage	7.2e-63	50.4
WP_002399592.1\|2041369_2042293_-	recombinase RecT	Q708Q2	Streptococcus_phage	1.0e-65	53.8
WP_010706514.1\|2042282_2042615_-	hypothetical protein	NA	NA	NA	NA
WP_002399594.1\|2042637_2042928_-	hypothetical protein	NA	NA	NA	NA
WP_002399595.1\|2043012_2043339_-	hypothetical protein	NA	NA	NA	NA
WP_002359948.1\|2043339_2043549_-	hypothetical protein	NA	NA	NA	NA
WP_002393142.1\|2043691_2043925_-	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_002399596.1\|2043957_2044485_-	hypothetical protein	NA	NA	NA	NA
WP_002399597.1\|2044542_2044740_-	hypothetical protein	NA	NA	NA	NA
WP_002399598.1\|2044729_2044951_-	helix-turn-helix transcriptional regulator	A0A290G4F8	Caldibacillus_phage	1.3e-06	42.4
WP_002399599.1\|2045100_2045460_+	helix-turn-helix transcriptional regulator	A8ATJ9	Listeria_phage	2.8e-19	45.0

DBSCAN-SWA_12

2255994 : 2262733

Streptococcus_phage(83.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_010773630.1\|2255994_2256822_-	phosphoadenosine phosphosulfate reductase family protein	Q24LD4	Clostridium_phage	1.4e-18	29.9
WP_002368731.1\|2256824_2257283_-	DUF3846 domain-containing protein	NA	NA	NA	NA
WP_002368732.1\|2257333_2258320_-	replication initiator protein A	A0A286QNA4	Streptococcus_phage	4.2e-17	40.2
WP_137274864.1\|2258689_2258938_-	hypothetical protein	NA	NA	NA	NA
WP_002359817.1\|2258995_2259496_-	antirestriction protein ArdA	A0A1S5SF25	Streptococcus_phage	6.8e-48	56.1
WP_002298822.1\|2259508_2259730_-	hypothetical protein	A0A1S5SEY0	Streptococcus_phage	4.5e-28	87.7
WP_010706533.1\|2259734_2259854_-	DUF3789 domain-containing protein	NA	NA	NA	NA
WP_002359815.1\|2259868_2261053_-	XRE family transcriptional regulator	A0A1S5SEX3	Streptococcus_phage	8.0e-140	61.1
WP_002359814.1\|2261310_2261565_-	hypothetical protein	NA	NA	NA	NA
WP_002387062.1\|2261590_2262733_-	DNA (cytosine-5-)-methyltransferase	A0A1S5SEK0	Streptococcus_phage	6.2e-121	60.0

DBSCAN-SWA_13

2662196 : 2671936

Streptococcus_phage(57.14%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_002385686.1\|2662196_2664380_+	anaerobic ribonucleoside-triphosphate reductase	A0A0C5KKX3	Enterococcus_phage	3.1e-286	66.8
WP_002356379.1\|2664412_2665009_+	anaerobic ribonucleoside-triphosphate reductase activating protein	A0A0C5K925	Enterococcus_phage	6.0e-51	56.4
WP_002362328.1\|2665053_2666172_-	DNA polymerase IV	NA	NA	NA	NA
WP_002356377.1\|2666297_2667056_-	iron export ABC transporter permease subunit FetB	NA	NA	NA	NA
WP_002356375.1\|2667039_2667702_-	ATP-binding cassette domain-containing protein	G3M9Y6	Bacillus_virus	6.7e-19	31.1
WP_002359438.1\|2667716_2668589_-	16S rRNA (cytidine(1402)-2'-O)-methyltransferase	M1PLC5	Streptococcus_phage	1.1e-80	57.2
WP_002356372.1\|2668700_2669048_-	DNA replication initiation control protein YabA	M1PFV3	Streptococcus_phage	8.1e-16	36.7
WP_002356371.1\|2669040_2669880_-	stage 0 sporulation family protein	NA	NA	NA	NA
WP_002384059.1\|2669996_2670947_-	DNA polymerase III subunit delta'	M1NSC1	Streptococcus_phage	6.2e-34	33.0
WP_002356367.1\|2670948_2671278_-	hypothetical protein	NA	NA	NA	NA
WP_002356366.1\|2671297_2671936_-	dTMP kinase	M1PSC7	Streptococcus_phage	2.1e-54	53.8

DBSCAN-SWA_14

2692732 : 2741423

Enterococcus_phage(35.9%)

transposase,plate,capsid,head,integrase,protease,terminase,tail,holin,tRNA,portal

attL 2707556:2707570|attR 2738657:2738671

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_002362481.1\|2692732_2693443_-\|protease	rhomboid family intramembrane serine protease	NA	NA	NA	NA
WP_002384041.1\|2693453_2693996_-	5-formyltetrahydrofolate cyclo-ligase	NA	NA	NA	NA
WP_011109565.1\|2694083_2694854_-	alpha/beta fold hydrolase	NA	NA	NA	NA
WP_002356327.1\|2695019_2695595_+	DUF805 domain-containing protein	NA	NA	NA	NA
WP_002387214.1\|2695685_2697251_+	membrane protein	NA	NA	NA	NA
WP_002397478.1\|2697202_2698336_+	DUF4950 domain-containing protein	C9E2L5	Enterococcus_phage	6.1e-20	51.5
WP_002387217.1\|2698594_2699659_-	FUSC family protein	NA	NA	NA	NA
WP_002387218.1\|2699914_2700112_-	hypothetical protein	NA	NA	NA	NA
WP_000997695.1\|2701328_2702507_-\|transposase	IS256-like element ISEf1 family transposase	NA	NA	NA	NA
WP_002415467.1\|2703542_2704844_-	LysM peptidoglycan-binding domain-containing protein	D2J077	Enterococcus_phage	1.7e-231	96.1
WP_002367246.1\|2704846_2705053_-\|holin	holin	A0A0S2MYF6	Enterococcus_phage	3.4e-30	98.5
WP_002383824.1\|2705055_2705289_-\|holin	holin	D2J075	Enterococcus_phage	1.2e-23	69.0
WP_002380794.1\|2705323_2705461_-	XkdX family protein	NA	NA	NA	NA
WP_010714092.1\|2705460_2705835_-	hypothetical protein	NA	NA	NA	NA
WP_010714093.1\|2705849_2706401_-	hypothetical protein	NA	NA	NA	NA
WP_002383822.1\|2706400_2706718_-	hypothetical protein	NA	NA	NA	NA
WP_002383821.1\|2706710_2707028_-	hypothetical protein	NA	NA	NA	NA
WP_010714094.1\|2707020_2707929_-\|plate	phage baseplate upper protein	Q9AYV5	Lactococcus_phage	1.1e-11	26.7
2707556:2707570	attL	NA	NA	NA	NA
WP_010714095.1\|2707947_2710743_-	CHAP domain-containing protein	D7RWE0	Brochothrix_phage	1.9e-62	70.1
WP_002415248.1\|2710739_2711444_-	hypothetical protein	NA	NA	NA	NA
WP_010714097.1\|2711449_2713753_-\|tail	phage tail tape measure protein	V5UPR9	Enterococcus_phage	2.4e-79	56.0
WP_002380802.1\|2713944_2714400_-	hypothetical protein	A0A2H4J956	uncultured_Caudovirales_phage	2.6e-14	37.4
WP_025187539.1\|2714399_2715035_-\|tail	tail protein	A0A2H4JGN2	uncultured_Caudovirales_phage	2.0e-28	34.5
WP_002385662.1\|2715040_2715403_-	HK97 gp10 family phage protein	NA	NA	NA	NA
WP_002385661.1\|2715392_2715731_-	hypothetical protein	A0A1B0T6B7	Bacillus_phage	4.9e-26	54.1
WP_002365100.1\|2715720_2716047_-\|head	phage head closure protein	A0A0N7IRA3	Lactobacillus_phage	1.7e-20	52.4
WP_002385660.1\|2716024_2716315_-\|head,tail	phage gp6-like head-tail connector protein	A0A1B1P7M9	Bacillus_phage	7.4e-23	64.3
WP_002415255.1\|2716307_2717672_-\|capsid	phage major capsid protein	A0A1B2APY9	Phage_Wrath	1.3e-125	67.6
WP_002385658.1\|2717684_2718257_-\|head,protease	HK97 family phage prohead protease	A0A2H4J6Z9	uncultured_Caudovirales_phage	1.1e-62	62.4
WP_010714098.1\|2718228_2719455_-\|portal	phage portal protein	A0A2H4J9C7	uncultured_Caudovirales_phage	3.2e-147	66.3
WP_010706848.1\|2719473_2721201_-\|terminase	terminase large subunit	A0A2H4JDG5	uncultured_Caudovirales_phage	8.4e-255	70.7
WP_010714099.1\|2721197_2721650_-	hypothetical protein	A0A2H4JFK0	uncultured_Caudovirales_phage	6.1e-48	68.5
WP_002365108.1\|2721760_2722135_-	HNH endonuclease	A0A1B0T6C5	Bacillus_phage	2.0e-44	68.3
WP_010714100.1\|2722134_2722542_-	hypothetical protein	A0A1B1P7N8	Bacillus_phage	4.4e-13	39.4
WP_002358088.1\|2723069_2723537_-	ArpU family transcriptional regulator	D7RWH7	Brochothrix_phage	1.4e-07	27.2
WP_046091376.1\|2723744_2724026_-	hypothetical protein	D2IZL5	Enterococcus_phage	1.4e-26	83.1
WP_010714102.1\|2724160_2724343_-	hypothetical protein	C9E2P1	Enterococcus_phage	8.2e-20	80.0
WP_080113513.1\|2724356_2724512_-	DUF3850 domain-containing protein	C9E2N9	Enterococcus_phage	1.6e-19	91.8
WP_010714105.1\|2724835_2725654_+	DUF4393 domain-containing protein	E9LUL1	Lactobacillus_phage	7.0e-26	31.2
WP_002395701.1\|2725811_2726018_-	hypothetical protein	A0A1B1V001	Enterococcus_phage	8.7e-26	100.0
WP_010714107.1\|2726036_2726639_-	hypothetical protein	NA	NA	NA	NA
WP_010706850.1\|2726658_2727129_-	DUF1064 domain-containing protein	A0A1I9KKZ1	Lactobacillus_phage	8.4e-32	45.9
WP_002393796.1\|2727277_2727547_-	hypothetical protein	NA	NA	NA	NA
WP_002370005.1\|2727685_2728537_-	ATP-binding protein	U5PVD6	Bacillus_phage	6.4e-22	33.3
WP_010714108.1\|2728548_2729337_-	DnaD domain protein	A0A0N7IRA7	Lactobacillus_phage	1.4e-52	53.2
WP_002393795.1\|2729352_2730168_-	hypothetical protein	J7KGZ1	Streptococcus_phage	8.7e-61	50.6
WP_002393794.1\|2730130_2731147_-	recombinase RecT	A0A1S5SAA8	Streptococcus_phage	2.2e-61	44.5
WP_002370012.1\|2731249_2731474_-	hypothetical protein	D2IZX4	Enterococcus_phage	4.9e-22	67.1
WP_002385643.1\|2731470_2731770_-	hypothetical protein	NA	NA	NA	NA
WP_010785685.1\|2731836_2732016_-	hypothetical protein	A0A0S2MY96	Enterococcus_phage	2.2e-17	75.4
WP_002385641.1\|2732051_2732321_-	hypothetical protein	NA	NA	NA	NA
WP_002385638.1\|2732396_2732711_+	hypothetical protein	NA	NA	NA	NA
WP_002385636.1\|2732835_2733012_-	helix-turn-helix domain-containing protein	D2IZW2	Enterococcus_phage	1.3e-14	65.5
WP_002385635.1\|2733095_2733479_+	DUF2513 domain-containing protein	A0A2H4J4K9	uncultured_Caudovirales_phage	3.4e-15	38.8
WP_002385634.1\|2733475_2733694_-	DUF2829 domain-containing protein	NA	NA	NA	NA
WP_002385633.1\|2733990_2734323_+	helix-turn-helix transcriptional regulator	A0A097QQ00	Enterococcus_phage	7.4e-35	68.2
WP_002385632.1\|2734341_2734686_+	ImmA/IrrE family metallo-endopeptidase	A0A097QQ08	Enterococcus_phage	3.9e-47	78.9
WP_002385631.1\|2734743_2735472_+	ion transporter	A0A1B0Y2S3	Lactobacillus_phage	1.0e-15	50.3
WP_010774242.1\|2735626_2736808_+\|integrase	site-specific integrase	Q9AZK8	Lactococcus_phage	5.5e-48	31.8
WP_002356321.1\|2736910_2737060_-	50S ribosomal protein L33	NA	NA	NA	NA
WP_010706862.1\|2737185_2739321_-	penicillin-binding protein 2	NA	NA	NA	NA
2738657:2738671	attR	NA	NA	NA	NA
WP_002356319.1\|2739485_2741423_-\|tRNA	threonine--tRNA ligase	A0A2K9L297	Tupanvirus	4.0e-112	36.3

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

3. NC_004671

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Crispr_ID: NC_004671_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_004671_1

525-656

Orphan

Consensus_repeat	Method
TTTCGAAAGTGGGAAAAACCAAC	CRISPRCasFinder
TTCGTTCGAAAGTGGGAAAAACCAACC	PILER-CR

2 spacers

The CRISPR arrays of NC_004671_1

>merge|NC_004671|1|525-656|CRISPRCasFinder,PILER-CR
TCCCGAAAGTGGGAAAAACCAACCTTCGGATAAACATGATAAAATCGGCGTTTCTTTCGAAAGTGGGAAAAACCAACGTCCAGAAGAATCCAATAATACCAGTACTTTGTTCGAAAGTGGGAAAAACCAACC

>NC_004671|1|1|525-655|CRISPRCasFinder
TCCCGAAAGTGGGAAAAACCAAC	CTTCGGATAAACATGATAAAATCGGCGTTTC
TTTCGAAAGTGGGAAAAACCAAC	GTCCAGAAGAATCCAATAATACCAGTACTTT
GTTCGAAAGTGGGAAAAACCAAC

>NC_004671|1|1|528-656|PILER-CR
CGAAAGTGGGAAAAACCAACCTTCGGA	TAAACATGATAAAATCGGCGTTTCTTT
CGAAAGTGGGAAAAACCAACGTCCAGA	AGAATCCAATAATACCAGTACTTTGTT
CGAAAGTGGGAAAAACCAACC

Protein	Signature genes	Signature genes Name	Protein_function
NC_004671.1\|WP_011109619.1\|7091_9767_+\|surface-exclusion-protein-SEA1/PrgA	unknown	unknown	gnl\|CDD\|275124
NC_004671.1\|WP_002367672.1\|13938_14295_+\|pheromone-response-system-RNA-binding-regulator-PrgU	unknown	unknown	gnl\|CDD\|286680
NC_004671.1\|WP_010717212.1\|1279_2437_+\|TraB/GumN-family-protein	unknown	unknown	gnl\|CDD\|224828
NC_004671.1\|WP_002367673.1\|14322_15180_+\|pheromone-response-LPXTG-anchored-adhesin-PrgC	unknown	unknown	gnl\|CDD\|185628
NC_004671.1\|WP_002365885.1\|5821_6202_+\|PrgR	unknown	unknown	unknown
NC_004671.1\|WP_011109620.1\|15221_16121_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|319758
NC_004671.1\|WP_049084809.1\|4100_5081_-\|hypothetical-protein	unknown	unknown	unknown
NC_004671.1\|WP_002365857.1\|16140_16575_+\|hypothetical-protein	unknown	unknown	unknown
NC_004671.1\|WP_002395058.1\|9959_13877_+\|LPXTG-anchored-aggregation-substance-PrgB/Asc10	unknown	unknown	gnl\|CDD\|369832
NC_004671.1\|WP_002406527.1\|2485_4075_+\|peptide-ABC-transporter-substrate-binding-protein	unknown	unknown	gnl\|CDD\|173869

Protein	Function_ID	Function_description	E-value
NC_004671.1\|WP_011109619.1\|7091_9767_+\|surface-exclusion-protein-SEA1/PrgA	gnl\|CDD\|275124	TIGR04320, hypothetical_protein, SEC10/PgrA surface exclusion domain. This model describes a conserved domain found in surface proteins of a number of Firmutes. Many members have LPXTG C-terminal anchoring motifs and a substantial number have the KxYKxGKxW putative sorting signal at the N-terminus. The tetracycline resistance plasmid pCF10 in Enterococcus faecalis promotes conjugal plasmid transfer in response to sex pheromones, but PgrA/Sec10 encoded by that plasmid, a member of this family, specifically inhibits the ability of cells to receive homologous plasmids. The phenomenon is called surface exclusion.	1.54312e-41
NC_004671.1\|WP_002367672.1\|13938_14295_+\|pheromone-response-system-RNA-binding-regulator-PrgU	gnl\|CDD\|286680	pfam09627, PrgU, PrgU-like protein. This hypothetical protein of 125 residues is expressed in bacteria but is thought to be plasmid in origin. It forms a six beta-strand barrel with three accompanying alpha helices and is probably a homo-dimer in the cell. It may be involved in pheromone-inducible conjugation.	2.88662e-62
NC_004671.1\|WP_010717212.1\|1279_2437_+\|TraB/GumN-family-protein	gnl\|CDD\|224828	COG1916, COG1916, Uncharacterized homolog of PrgY (pheromone shutdown protein) [Function unknown].	3.63706e-89
NC_004671.1\|WP_002367673.1\|14322_15180_+\|pheromone-response-LPXTG-anchored-adhesin-PrgC	gnl\|CDD\|185628	PTZ00449, PTZ00449, 104 kDa microneme/rhoptry antigen; Provisional.	8.67929e-13
NC_004671.1\|WP_011109620.1\|15221_16121_+\|hypothetical-protein	gnl\|CDD\|319758	cd16427, TraM-like, C-terminal domain of transfer protein TraM. This family contains the C-terminal domain of transfer protein TraM of the G+ broad host range Enterococcus conjugative plasmid pIP501 and similar proteins. The protein localizes to the cell envelope and is part of the plasmid transfer system that is accessible from outside of the cell. TraM displays a fold similar to the type IV secretion system (T4SS) VirB8 proteins from A. tumefaciens and B. suis (G-) and to the transfer protein TcpC from C. perfringens plasmid pCW3 (G+), reinforcing the prediction that TraM performs a key role in the secretion process, which is underlined by its surface accessibility. It is also structurally related to members of the nuclear transport factor-2 (NTF-2)-like superfamily with a high similarity to the NTF-2 protein from Rattus norvegicus. TraM (categorized as T4SS VirB8-like class GAMMA) does not possess the binding pocket of classic VirB8 class ALPHA proteins, recognized by VirB8 interaction inhibitors.	4.43758e-21
NC_004671.1\|WP_002395058.1\|9959_13877_+\|LPXTG-anchored-aggregation-substance-PrgB/Asc10	gnl\|CDD\|369832	pfam08363, GbpC, Glucan-binding protein C. This domain is found in the Streptococcus Glucan-binding protein C (GbpC) and also in surface protein antigen (Spa)-family proteins which show sequence similarity to GbpC.	1.39785e-72
NC_004671.1\|WP_002406527.1\|2485_4075_+\|peptide-ABC-transporter-substrate-binding-protein	gnl\|CDD\|173869	cd08504, PBP2_OppA, The substrate-binding component of an ABC-type oligopetide import system contains the type 2 periplasmic binding fold. This family represents the periplasmic substrate-binding component of an ATP-binding cassette (ABC)-type oligopeptide transport system comprised of 5 subunits. The transport system OppABCDEF contains two homologous integral membrane proteins OppB and OppF that form the translocation pore; two homologous nucleotide-binding domains OppD and OppF that drive the transport process through binding and hydrolysis of ATP; and the substrate-binding protein or receptor OppA that determines the substrate specificity of the transport system. The dipeptide (DppA) and oligopeptide (OppA) binding proteins differ in several ways. The DppA binds dipeptides and some tripeptides and is involved in chemotaxis toward dipeptides, whereas the OppA binds peptides of a wide range of lengths (2-35 amino acid residues) and plays a role in recycling of cell wall peptides, which precludes any involvement in chemotaxis. Most of other periplasmic binding proteins are comprised of only two globular subdomains corresponding to domains I and III of the dipeptide/oligopeptide binding proteins. The structural topology of these domains is most similar to that of the type 2 periplasmic binding proteins (PBP2), which are responsible for the uptake of a variety of substrates such as phosphate, sulfate, polysaccharides, lysine/arginine/ornithine, and histidine. The PBP2 bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap. After binding their specific ligand with high affinity, they can interact with a cognate membrane transport complex comprised of two integral membrane domains and two cytoplasmically located ATPase domains. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis. Besides transport proteins, the PBP2 superfamily includes the ligand-binding domains from ionotropic glutamate receptors, LysR-type transcriptional regulators, and unorthodox sensor proteins involved in signal transduction.	0

>NC_004671.1|WP_010717212.1|1279_2437_+|TraB/GumN-family-protein
MEEDIVRLFYKGSEIILIGTSHISAESADLVRKTIQEENPDTICIEWDQKRYKKNIHPDEWDDTDIVKIIKNKQFPVFIFGVIYKLFQKKVSQDMNSLVGKEFVVAVDESKKLNIKFYLIDRDSSLTFKRAWRMLNFREKVKLPYAFGKIFEGAEETEEEVQNLLESENFEPVFEELKESYPNLWEVFVTERDDYLATKIQNTANGKTVAVLGKAHLKGVSDRLKNNQKSDLQKLEIIPPKKFGSKLLEWIIPGILLILLGVSFYQGTQVGIEQLLRWLLWNGGLAALFTVFALGHPLTVLTSLIFAPLATLLPMVSVGVFSAIVEATVRKPKVKDFQTMDLDLQSIKTIYKNRVLRVFLVFFLSSLGGLLGNIIGGLGIVKNLF
>NC_004671.1|WP_002406527.1|2485_4075_+|peptide-ABC-transporter-substrate-binding-protein
MLLVFASCGVNKSTEDSKKTNETKVEQIATLSAGTPVQSLDPATAVDQTSVTLLANVMEGLYRLDEKNQPQPAIAAGQPKISNGGKTYTIVIRDGAKWADGTDITADDFVTAWQRVLDPKTASPNVELFAAIKNAKEISIGKQQKETLGVKSKGNKTIEIELEEPTPYFTDLLALTAYFPVQQNAVKEYGKEYGTTKENIVTNGAFTLTDLNGVGISDKWTIAKNPKYWDKKHVAMEKIKFQVVKDINTGINLYNDGQLDDAPVAGEYSKQLENNKDFIRELSATTMFLEVNQRNKKSITSNKHARQAINFAIDREAISNKILTNGSIPAKGVVPSKLVYNPKTGKDFTNSSLVFLDKSKAKDSWEKAKKELKGTDLSIDIMVNEEDLSKKLGEYLQNELQDTLDGLKVSVTAVPATLQTERLNSGNFMIALSGWQADFADPVSFLANFESKSSLNHGGYANEEYDKLLKNNSSKRLQELKDAEKLILEDAGVIPLLQIGNAKLRNQKISEMKVHSIGAKYDYKTMEIK
>NC_004671.1|WP_049084809.1|4100_5081_-|hypothetical-protein
MVLFQPKLKECIILDYKELLEVLRKDLNFKKVDLYQEKSNKTRYREIELGEKSPTIEELISFTDTLGIRLSEFLYRGDITPLAASYYGKRKIEVASLINNFPELEKQFPEIYKDRFKNLQCYTLFTLCLIISKSLNNSLYTFKNKDIRELKNFYKNREVILGADYAILSHLYMAVPEYSNELDFLTEKLFPINQSYGDIHDHAVQLCIKNAVTVFLEKKDFEKADYFLEQFDIVRKVPSFILDGTINLEMIYLKHLRNFLKKRNMEEYLKAVNIVNLFSQLGENDTYKELVKEVTEIARKENFEVPSSLNIIADTFEGVGYLKSDK
>NC_004671.1|WP_002365885.1|5821_6202_+|PrgR
MIELKATDLHRITCQLTLFNRQRFKLYNGTTERIVYDFSGRNLLINPVSFETEQDMERFFRQVKLIYFDGKVVGYRGCSELPLKLECRAFKKMVKRQKMLLNAPFNYKVFEENEFREWCKKMRSYK
>NC_004671.1|WP_011109619.1|7091_9767_+|surface-exclusion-protein-SEA1/PrgA
MKKIASTGLSILVATGVAGIGGNEVQAAEQAQPKTPENSSTEQPTVKATQTTEQAITEKQQQVTEKQAIVDQKQQVADTAKKEKDAIDQSVKDQQAVVDQNKDALDQSQQAVTDQQAVVDEAKKVVDEATPSAIEKAKEQVATDTQAVDEQQKVVDQAQTDVNQQQAVVDEKAKETNAAKVQNEKDQQAVTAAKQEQAKLEELAKNAEAEKVKAEKEQAAKEAELANKQKEEAKAKDQKTKDDQAVADQQTVVTTSQEKVTDAKADTAAKQADLTAKENALKDKQAATKQAQNTLDNSKEELKGHKGINLPPKFSADYDTKLSAEEIATLEKTALEMNKNFPTSKEDEKNKDVMWDIQHLSADQKKELSVYTTELLNDVRKKLGLSQLSVSDQSIKFAWDIAKYSDTGEYMHDVIAINKAAKENGFKEYPGMNYYENLGGGYYETENGKVSKYTLQESIRKMLVNMLFDDGRLGYSHLHSLLQDGKTALGVSLSGEKNSISPKIHIISYGKEKLEDSSQYQNGEVASMKSKEELQQEIASNQEKLATAQQAESDAQQARSASQQALNTAKTTQATAEKELSVHKATLANLQAVATKSTTNYEEKVRQTATAEKSLQQTKDQLATINELIQNRAAVLEKAKTNVAEAQAIEQTSAKVLKEKQEAQKAEENTLNSLKEVLDLAKENLNQKQVALKTSTRSLSRLENAQPTYEKALNELNKAEAAVVQAQEAYENSMKSLEELKEQQAVATLAYAQAQEDLSNAKLELQQYQGVLRDLEAQQAEQRRQEALQEQVAKEQQRLEREAKQNQTLVASATSADKTPGLQQLSFSKQKEQPKAQALTHSEPRKTKQVAKAPESLPQTGEQQSIWLTIIGLLMAAGTINFKNKKRKKNS
>NC_004671.1|WP_002395058.1|9959_13877_+|LPXTG-anchored-aggregation-substance-PrgB/Asc10
MNQQTEVKKRFKMYKAKKHWIVAPILFLGVLGVVGLATDNVQAAELDTQPGSTTVHPDNPDPQLGSATPNTAVSEESAVQKDTTSQPTKAEEVASEKNGAEQSSATPNDTTNVQQPTVGAEKSAQEQPVVSPETTNEPLGQPTEVAPAENEANKSTSILKEFETPDVDKAVDEAKKDPNITVVEKPAEDLGNVSSKDLAAKEKEVDQLQKEQAKKIAQQAAELKAKNEKIAKENAEIAAKNKAEKERYEKEVAEYNKHKNENSYVNEAISKNLVFDQSVVTKDTKISSIKGGKFIKATDFNKVNAGDSKDIFTKLRKDMGGKATGNFQNSFVKEANLGSNGGYAVLLEKNKPVTVTYTGLNASYLGRKITKAEFVYELQSSPSQSGTLNAVFSNDPIITAFIGTNRVNGKDVKTRLTIKFFDASGKEVLPDKDSPFAYALSSLNSSLTNKGGHAEFVSDFGANNAFKYINGSYVKKQADGKFYSPEDIDYGTGPSGLKNSDWDAVGHKNAYFGSGVGLANGRISFSFGMTTKGKSNVPVSSAQWFAFSTNLNAQSVKPIFNYGNPKEPEKATIEFNGYKANVVPVLVPNKEVTDGQKNINDLNVKRGDSLQYIVTGDTTELAKVDPKTVTKQGIRDTFDAEKVTIDLSKVKVYQADASLNEKDLKAVAAAINSGKAKDVTASYDLNLDQNTVTAMMKTNADGSVVLAMGYKYLLVLPFVVKNVEGDFENTAVQLTNDGETVTNTVINHVPSSNPSKDVKADKNGTVGSVSLHDKDIPLQTKIYYEVKSSERPANYGGITEEWGMNDVLDTTHDRFTGKWHAITNYDLKVGDKTLKAGTDISAYILLENKDNKDLTFTMNQALLAALNEGSNKVGKQAWSVYLEVERIKTGDVENTQTENYNKELVRSNTVVTHTPDDPKPTKAVHNKKGEDINHGKVARGDVLSYEMTWDLKGYDKDFAFDTVDLATGVSFFDDYDETKVTPIKDLLRVKDSKGVDITNQFTISWDDAKGTVTISAKDPQAFILAYGGQELRVTLPTKVKADVSGDVYNSAEQNTFGQRIKTNTVVNHIPKVNPKKDVVIKVGDKQSQNGATIKLGEKFFYEFTSSDIPAEYAGVVEEWSISDKLDVKHDKFSGQWSVFANSNFVLADGTKVNKGDDISKLFTMTFDKGVVKITASQAFLDAMNLKENKNVAHSWKAFIGVERIAAGDVYNTIEESFNNEKIKTNTVVTHTPEKPQTPPEKTVIVPPTPKTPQAPVEPLVVEKASVVPELPKTGEKQNVLLTVVGSLAAMLGLAGLGFKRRKETK
>NC_004671.1|WP_002367672.1|13938_14295_+|pheromone-response-system-RNA-binding-regulator-PrgU
MEAVVAEREAKGMKEIAIQEKDLTLQWRGNTGKLVKVRLKNTRAMEMWYNKQITEENIQEITTLNIIKNGKSLALEVYPEKSIYVKPNLGRINVPVFFIKTPINRGIFEEIFGETLKS
>NC_004671.1|WP_002367673.1|14322_15180_+|pheromone-response-LPXTG-anchored-adhesin-PrgC
MKKIILSSLFSAVLVFGGGSITAFADDLGPTDPATPPITEPTDSSEPTNPTEPVDPAEPPVIPTDPTEPSKPTEPTTPSEPEKPTEPTTPIDPGTPVEPTEPSEPTEPSQPTEPTTPSEPEKPVTPEQPKEPTQPVIPEKPAEPETPKTPEQPTKPIDVVVTPSGEIDKTNQSAGTQPSIPIETSNLAEVTHVPSETTPITTEAGEEIVAVDKGVPLTKTPEGLKPISSSYKVLPSGNVEVKASDGKMKVLPHTGEKFTLLFSVLGSFFVLISGFFFFKKNKKKA
>NC_004671.1|WP_011109620.1|15221_16121_+|hypothetical-protein
MLCLFILFTTKQSHVLLNELGFNRKIDLVQGIEQLTKINADLKKSTDRILITYEIYYNVTDEKAFLRETMTLPVVEETVLQNMVQTVETNEEVRQEDLEAFLYLFKRNVSNKSKRIGRSTGSLKKKAEKQQKSTVFTTISRYSYFSVALLIFLAVGVFTGASFGSQSKPTSQNDSKLEERLTHLQEQVHEQPQVDVVARFFLSSLYSGEESDKATQKQVKKYVSEGVLKEIKGSKEQIRTLFLWESKKEGNQWLLTYVVTLKVAKEETEIRQMKVAMEKKNNNYQVTELPEEKEFTINE
>NC_004671.1|WP_002365857.1|16140_16575_+|hypothetical-protein
MKYERPLKRESQIKEFELGTHAAVIEKVQKKRSQKGNDMFLLSLLGKSNEKGVYFLTFGNDYTEDNLRYILASIQDNGVEIPDVDFGYNRETFEFLKGKDVYIQVEEQEYKGKVKHAVTNFLTQDEFEESEEMEFSESNTEEDW

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NC_004671_1	1.1\|548\|31\|NC_004671\|CRISPRCasFinder	548-578	31	NC_004671	Enterococcus faecalis V583 plasmid pTEF2, complete sequence	548-578	0	1.0
NC_004671_1	1.1\|548\|31\|NC_004671\|CRISPRCasFinder	548-578	31	NZ_CP015885	Enterococcus faecalis strain sorialis plasmid Efsorialis-p2, complete sequence	461-491	0	1.0
NC_004671_1	1.1\|548\|31\|NC_004671\|CRISPRCasFinder	548-578	31	NZ_CP040897	Enterococcus faecalis strain HA-1 plasmid punnamed	33655-33685	0	1.0
NC_004671_1	1.1\|548\|31\|NC_004671\|CRISPRCasFinder	548-578	31	NZ_CP046109	Enterococcus faecalis strain 133170041-3 plasmid pAD1, complete sequence	449-479	0	1.0
NC_004671_1	1.1\|548\|31\|NC_004671\|CRISPRCasFinder	548-578	31	NZ_CP028837	Enterococcus faecalis strain FC plasmid unnamed2, complete sequence	5472-5502	0	1.0
NC_004671_1	1.1\|548\|31\|NC_004671\|CRISPRCasFinder	548-578	31	NZ_CP030046	Enterococcus faecalis strain C54 plasmid pC54, complete sequence	43942-43972	0	1.0
NC_004671_1	1.1\|548\|31\|NC_004671\|CRISPRCasFinder	548-578	31	NC_011642	Enterococcus faecalis plasmid pMG2200, complete sequence	83451-83481	0	1.0
NC_004671_1	1.1\|548\|31\|NC_004671\|CRISPRCasFinder	548-578	31	NZ_CP028284	Enterococcus faecalis strain FDAARGOS_324 plasmid unnamed2, complete sequence	4997-5027	0	1.0
NC_004671_1	1.1\|548\|31\|NC_004671\|CRISPRCasFinder	548-578	31	NZ_CP030043	Enterococcus faecalis strain C25 plasmid pC25-1, complete sequence	773-803	0	1.0
NC_004671_1	1.2\|602\|31\|NC_004671\|CRISPRCasFinder	602-632	31	CP002494	Enterococcus faecalis 62 plasmid EF62pC, complete sequence	7642-7672	0	1.0
NC_004671_1	1.2\|602\|31\|NC_004671\|CRISPRCasFinder	602-632	31	MH830362	Enterococcus faecalis plasmid p4, complete sequence	66170-66200	0	1.0
NC_004671_1	1.2\|602\|31\|NC_004671\|CRISPRCasFinder	602-632	31	NZ_CP031028	Enterococcus faecalis strain TY1 isolate flatfish plasmid pDEF-1, complete sequence	12175-12205	0	1.0
NC_004671_1	1.2\|602\|31\|NC_004671\|CRISPRCasFinder	602-632	31	NZ_CP019514	Enterococcus faecalis strain CLB21560 plasmid pB, complete sequence	60905-60935	0	1.0
NC_004671_1	1.2\|602\|31\|NC_004671\|CRISPRCasFinder	602-632	31	NZ_CP036248	Enterococcus faecalis R712 plasmid pR712_02, complete sequence	92753-92783	0	1.0
NC_004671_1	1.2\|602\|31\|NC_004671\|CRISPRCasFinder	602-632	31	NZ_CP030046	Enterococcus faecalis strain C54 plasmid pC54, complete sequence	43888-43918	0	1.0
NC_004671_1	1.2\|602\|31\|NC_004671\|CRISPRCasFinder	602-632	31	NZ_CP028284	Enterococcus faecalis strain FDAARGOS_324 plasmid unnamed2, complete sequence	4943-4973	0	1.0
NC_004671_1	1.2\|602\|31\|NC_004671\|CRISPRCasFinder	602-632	31	NZ_KY513281	Enterococcus faecalis strain 6742 plasmid p6742_2, complete sequence	5073-5103	0	1.0
NC_004671_1	1.2\|602\|31\|NC_004671\|CRISPRCasFinder	602-632	31	NC_004671	Enterococcus faecalis V583 plasmid pTEF2, complete sequence	602-632	0	1.0
NC_004671_1	1.2\|602\|31\|NC_004671\|CRISPRCasFinder	602-632	31	NZ_CP015885	Enterococcus faecalis strain sorialis plasmid Efsorialis-p2, complete sequence	515-545	0	1.0
NC_004671_1	1.2\|602\|31\|NC_004671\|CRISPRCasFinder	602-632	31	NZ_CP040897	Enterococcus faecalis strain HA-1 plasmid punnamed	33709-33739	0	1.0
NC_004671_1	1.2\|602\|31\|NC_004671\|CRISPRCasFinder	602-632	31	NZ_CP046109	Enterococcus faecalis strain 133170041-3 plasmid pAD1, complete sequence	503-533	0	1.0
NC_004671_1	1.2\|602\|31\|NC_004671\|CRISPRCasFinder	602-632	31	NZ_CP049777	Enterococcus faecalis strain ES-1 plasmid unnamed2, complete sequence	503-533	0	1.0
NC_004671_1	1.2\|602\|31\|NC_004671\|CRISPRCasFinder	602-632	31	NZ_CP028837	Enterococcus faecalis strain FC plasmid unnamed2, complete sequence	5526-5556	0	1.0
NC_004671_1	1.2\|602\|31\|NC_004671\|CRISPRCasFinder	602-632	31	NC_011642	Enterococcus faecalis plasmid pMG2200, complete sequence	83505-83535	0	1.0
NC_004671_1	1.2\|602\|31\|NC_004671\|CRISPRCasFinder	602-632	31	LC499744	Enterococcus faecalis S7316 plasmid pS7316optrA DNA, complete sequence	9536-9566	0	1.0
NC_004671_1	1.2\|602\|31\|NC_004671\|CRISPRCasFinder	602-632	31	NZ_CP030043	Enterococcus faecalis strain C25 plasmid pC25-1, complete sequence	827-857	0	1.0
NC_004671_1	1.3\|555\|27\|NC_004671\|PILER-CR	555-581	27	NZ_CP030046	Enterococcus faecalis strain C54 plasmid pC54, complete sequence	43945-43971	0	1.0
NC_004671_1	1.3\|555\|27\|NC_004671\|PILER-CR	555-581	27	NZ_CP028284	Enterococcus faecalis strain FDAARGOS_324 plasmid unnamed2, complete sequence	5000-5026	0	1.0
NC_004671_1	1.3\|555\|27\|NC_004671\|PILER-CR	555-581	27	NC_004671	Enterococcus faecalis V583 plasmid pTEF2, complete sequence	549-575	0	1.0
NC_004671_1	1.3\|555\|27\|NC_004671\|PILER-CR	555-581	27	NZ_CP015885	Enterococcus faecalis strain sorialis plasmid Efsorialis-p2, complete sequence	462-488	0	1.0
NC_004671_1	1.3\|555\|27\|NC_004671\|PILER-CR	555-581	27	NZ_CP040897	Enterococcus faecalis strain HA-1 plasmid punnamed	33656-33682	0	1.0
NC_004671_1	1.3\|555\|27\|NC_004671\|PILER-CR	555-581	27	NZ_CP046109	Enterococcus faecalis strain 133170041-3 plasmid pAD1, complete sequence	450-476	0	1.0
NC_004671_1	1.3\|555\|27\|NC_004671\|PILER-CR	555-581	27	NZ_CP028837	Enterococcus faecalis strain FC plasmid unnamed2, complete sequence	5473-5499	0	1.0
NC_004671_1	1.3\|555\|27\|NC_004671\|PILER-CR	555-581	27	NC_011642	Enterococcus faecalis plasmid pMG2200, complete sequence	83452-83478	0	1.0
NC_004671_1	1.3\|555\|27\|NC_004671\|PILER-CR	555-581	27	NZ_CP030043	Enterococcus faecalis strain C25 plasmid pC25-1, complete sequence	774-800	0	1.0
NC_004671_1	1.4\|609\|27\|NC_004671\|PILER-CR	609-635	27	CP002494	Enterococcus faecalis 62 plasmid EF62pC, complete sequence	7645-7671	0	1.0
NC_004671_1	1.4\|609\|27\|NC_004671\|PILER-CR	609-635	27	MH830362	Enterococcus faecalis plasmid p4, complete sequence	66173-66199	0	1.0
NC_004671_1	1.4\|609\|27\|NC_004671\|PILER-CR	609-635	27	NZ_CP031028	Enterococcus faecalis strain TY1 isolate flatfish plasmid pDEF-1, complete sequence	12178-12204	0	1.0
NC_004671_1	1.4\|609\|27\|NC_004671\|PILER-CR	609-635	27	NZ_CP019514	Enterococcus faecalis strain CLB21560 plasmid pB, complete sequence	60908-60934	0	1.0
NC_004671_1	1.4\|609\|27\|NC_004671\|PILER-CR	609-635	27	NZ_CP036248	Enterococcus faecalis R712 plasmid pR712_02, complete sequence	92756-92782	0	1.0
NC_004671_1	1.4\|609\|27\|NC_004671\|PILER-CR	609-635	27	NZ_CP030046	Enterococcus faecalis strain C54 plasmid pC54, complete sequence	43891-43917	0	1.0
NC_004671_1	1.4\|609\|27\|NC_004671\|PILER-CR	609-635	27	NZ_CP028284	Enterococcus faecalis strain FDAARGOS_324 plasmid unnamed2, complete sequence	4946-4972	0	1.0
NC_004671_1	1.4\|609\|27\|NC_004671\|PILER-CR	609-635	27	NZ_KY513281	Enterococcus faecalis strain 6742 plasmid p6742_2, complete sequence	5074-5100	0	1.0
NC_004671_1	1.4\|609\|27\|NC_004671\|PILER-CR	609-635	27	NC_004671	Enterococcus faecalis V583 plasmid pTEF2, complete sequence	603-629	0	1.0
NC_004671_1	1.4\|609\|27\|NC_004671\|PILER-CR	609-635	27	NZ_CP015885	Enterococcus faecalis strain sorialis plasmid Efsorialis-p2, complete sequence	516-542	0	1.0
NC_004671_1	1.4\|609\|27\|NC_004671\|PILER-CR	609-635	27	NZ_CP040897	Enterococcus faecalis strain HA-1 plasmid punnamed	33710-33736	0	1.0
NC_004671_1	1.4\|609\|27\|NC_004671\|PILER-CR	609-635	27	NZ_CP046109	Enterococcus faecalis strain 133170041-3 plasmid pAD1, complete sequence	504-530	0	1.0
NC_004671_1	1.4\|609\|27\|NC_004671\|PILER-CR	609-635	27	NZ_CP049777	Enterococcus faecalis strain ES-1 plasmid unnamed2, complete sequence	504-530	0	1.0
NC_004671_1	1.4\|609\|27\|NC_004671\|PILER-CR	609-635	27	NZ_CP028837	Enterococcus faecalis strain FC plasmid unnamed2, complete sequence	5527-5553	0	1.0
NC_004671_1	1.4\|609\|27\|NC_004671\|PILER-CR	609-635	27	NC_011642	Enterococcus faecalis plasmid pMG2200, complete sequence	83506-83532	0	1.0
NC_004671_1	1.4\|609\|27\|NC_004671\|PILER-CR	609-635	27	LC499744	Enterococcus faecalis S7316 plasmid pS7316optrA DNA, complete sequence	9537-9563	0	1.0
NC_004671_1	1.4\|609\|27\|NC_004671\|PILER-CR	609-635	27	NZ_CP030043	Enterococcus faecalis strain C25 plasmid pC25-1, complete sequence	828-854	0	1.0
NC_004671_1	1.1\|548\|31\|NC_004671\|CRISPRCasFinder	548-578	31	CP002494	Enterococcus faecalis 62 plasmid EF62pC, complete sequence	7696-7726	1	0.968
NC_004671_1	1.1\|548\|31\|NC_004671\|CRISPRCasFinder	548-578	31	NZ_CP031028	Enterococcus faecalis strain TY1 isolate flatfish plasmid pDEF-1, complete sequence	12229-12259	1	0.968
NC_004671_1	1.1\|548\|31\|NC_004671\|CRISPRCasFinder	548-578	31	NZ_CP019514	Enterococcus faecalis strain CLB21560 plasmid pB, complete sequence	60959-60989	1	0.968
NC_004671_1	1.1\|548\|31\|NC_004671\|CRISPRCasFinder	548-578	31	NZ_CP036248	Enterococcus faecalis R712 plasmid pR712_02, complete sequence	92807-92837	1	0.968
NC_004671_1	1.2\|602\|31\|NC_004671\|CRISPRCasFinder	602-632	31	NC_013533	Enterococcus faecalis plasmid pBEE99, complete sequence	748-778	1	0.968
NC_004671_1	1.3\|555\|27\|NC_004671\|PILER-CR	555-581	27	CP002494	Enterococcus faecalis 62 plasmid EF62pC, complete sequence	7699-7725	1	0.963
NC_004671_1	1.3\|555\|27\|NC_004671\|PILER-CR	555-581	27	MH830362	Enterococcus faecalis plasmid p4, complete sequence	66227-66253	1	0.963
NC_004671_1	1.3\|555\|27\|NC_004671\|PILER-CR	555-581	27	NZ_CP031028	Enterococcus faecalis strain TY1 isolate flatfish plasmid pDEF-1, complete sequence	12232-12258	1	0.963
NC_004671_1	1.3\|555\|27\|NC_004671\|PILER-CR	555-581	27	NZ_CP019514	Enterococcus faecalis strain CLB21560 plasmid pB, complete sequence	60962-60988	1	0.963
NC_004671_1	1.3\|555\|27\|NC_004671\|PILER-CR	555-581	27	NZ_CP036248	Enterococcus faecalis R712 plasmid pR712_02, complete sequence	92810-92836	1	0.963
NC_004671_1	1.3\|555\|27\|NC_004671\|PILER-CR	555-581	27	NZ_CP049777	Enterococcus faecalis strain ES-1 plasmid unnamed2, complete sequence	450-476	1	0.963
NC_004671_1	1.4\|609\|27\|NC_004671\|PILER-CR	609-635	27	NC_013533	Enterococcus faecalis plasmid pBEE99, complete sequence	749-775	1	0.963
NC_004671_1	1.1\|548\|31\|NC_004671\|CRISPRCasFinder	548-578	31	MH830362	Enterococcus faecalis plasmid p4, complete sequence	66224-66254	2	0.935
NC_004671_1	1.1\|548\|31\|NC_004671\|CRISPRCasFinder	548-578	31	NZ_CP049777	Enterococcus faecalis strain ES-1 plasmid unnamed2, complete sequence	449-479	2	0.935
NC_004671_1	1.1\|548\|31\|NC_004671\|CRISPRCasFinder	548-578	31	NZ_KY513281	Enterococcus faecalis strain 6742 plasmid p6742_2, complete sequence	5019-5049	2	0.935
NC_004671_1	1.1\|548\|31\|NC_004671\|CRISPRCasFinder	548-578	31	NC_013533	Enterococcus faecalis plasmid pBEE99, complete sequence	694-724	2	0.935
NC_004671_1	1.1\|548\|31\|NC_004671\|CRISPRCasFinder	548-578	31	LC499744	Enterococcus faecalis S7316 plasmid pS7316optrA DNA, complete sequence	9482-9512	2	0.935
NC_004671_1	1.3\|555\|27\|NC_004671\|PILER-CR	555-581	27	NZ_KY513281	Enterococcus faecalis strain 6742 plasmid p6742_2, complete sequence	5020-5046	2	0.926
NC_004671_1	1.3\|555\|27\|NC_004671\|PILER-CR	555-581	27	NC_013533	Enterococcus faecalis plasmid pBEE99, complete sequence	695-721	2	0.926
NC_004671_1	1.3\|555\|27\|NC_004671\|PILER-CR	555-581	27	LC499744	Enterococcus faecalis S7316 plasmid pS7316optrA DNA, complete sequence	9483-9509	2	0.926
NC_004671_1	1.4\|609\|27\|NC_004671\|PILER-CR	609-635	27	MT711976	Streptomyces phage Coruscant, complete genome	87403-87429	5	0.815
NC_004671_1	1.4\|609\|27\|NC_004671\|PILER-CR	609-635	27	NC_023573	Staphylococcus phage phiSA012 DNA, complete genome	31964-31990	5	0.815
NC_004671_1	1.4\|609\|27\|NC_004671\|PILER-CR	609-635	27	JQ660954	Clostridium phage PhiS63, complete genome	22891-22917	6	0.778
NC_004671_1	1.2\|602\|31\|NC_004671\|CRISPRCasFinder	602-632	31	NC_023573	Staphylococcus phage phiSA012 DNA, complete genome	31963-31993	7	0.774
NC_004671_1	1.1\|548\|31\|NC_004671\|CRISPRCasFinder	548-578	31	NZ_CP022523	Pseudoalteromonas sp. NC201 plasmid pNC201, complete sequence	586541-586571	8	0.742
NC_004671_1	1.2\|602\|31\|NC_004671\|CRISPRCasFinder	602-632	31	MT711976	Streptomyces phage Coruscant, complete genome	87400-87430	8	0.742
NC_004671_1	1.2\|602\|31\|NC_004671\|CRISPRCasFinder	602-632	31	JQ660954	Clostridium phage PhiS63, complete genome	22890-22920	10	0.677

1. spacer 1.1|548|31|NC_004671|CRISPRCasFinder matches to NC_004671 (Enterococcus faecalis V583 plasmid pTEF2, complete sequence) position: , mismatch: 0, identity: 1.0

cttcggataaacatgataaaatcggcgtttc	CRISPR spacer
cttcggataaacatgataaaatcggcgtttc	Protospacer
*******************************

2. spacer 1.1|548|31|NC_004671|CRISPRCasFinder matches to NZ_CP015885 (Enterococcus faecalis strain sorialis plasmid Efsorialis-p2, complete sequence) position: , mismatch: 0, identity: 1.0

cttcggataaacatgataaaatcggcgtttc	CRISPR spacer
cttcggataaacatgataaaatcggcgtttc	Protospacer
*******************************

3. spacer 1.1|548|31|NC_004671|CRISPRCasFinder matches to NZ_CP040897 (Enterococcus faecalis strain HA-1 plasmid punnamed) position: , mismatch: 0, identity: 1.0

cttcggataaacatgataaaatcggcgtttc	CRISPR spacer
cttcggataaacatgataaaatcggcgtttc	Protospacer
*******************************

4. spacer 1.1|548|31|NC_004671|CRISPRCasFinder matches to NZ_CP046109 (Enterococcus faecalis strain 133170041-3 plasmid pAD1, complete sequence) position: , mismatch: 0, identity: 1.0

cttcggataaacatgataaaatcggcgtttc	CRISPR spacer
cttcggataaacatgataaaatcggcgtttc	Protospacer
*******************************

5. spacer 1.1|548|31|NC_004671|CRISPRCasFinder matches to NZ_CP028837 (Enterococcus faecalis strain FC plasmid unnamed2, complete sequence) position: , mismatch: 0, identity: 1.0

cttcggataaacatgataaaatcggcgtttc	CRISPR spacer
cttcggataaacatgataaaatcggcgtttc	Protospacer
*******************************

6. spacer 1.1|548|31|NC_004671|CRISPRCasFinder matches to NZ_CP030046 (Enterococcus faecalis strain C54 plasmid pC54, complete sequence) position: , mismatch: 0, identity: 1.0

cttcggataaacatgataaaatcggcgtttc	CRISPR spacer
cttcggataaacatgataaaatcggcgtttc	Protospacer
*******************************

7. spacer 1.1|548|31|NC_004671|CRISPRCasFinder matches to NC_011642 (Enterococcus faecalis plasmid pMG2200, complete sequence) position: , mismatch: 0, identity: 1.0

cttcggataaacatgataaaatcggcgtttc	CRISPR spacer
cttcggataaacatgataaaatcggcgtttc	Protospacer
*******************************

8. spacer 1.1|548|31|NC_004671|CRISPRCasFinder matches to NZ_CP028284 (Enterococcus faecalis strain FDAARGOS_324 plasmid unnamed2, complete sequence) position: , mismatch: 0, identity: 1.0

cttcggataaacatgataaaatcggcgtttc	CRISPR spacer
cttcggataaacatgataaaatcggcgtttc	Protospacer
*******************************

9. spacer 1.1|548|31|NC_004671|CRISPRCasFinder matches to NZ_CP030043 (Enterococcus faecalis strain C25 plasmid pC25-1, complete sequence) position: , mismatch: 0, identity: 1.0

cttcggataaacatgataaaatcggcgtttc	CRISPR spacer
cttcggataaacatgataaaatcggcgtttc	Protospacer
*******************************

10. spacer 1.2|602|31|NC_004671|CRISPRCasFinder matches to CP002494 (Enterococcus faecalis 62 plasmid EF62pC, complete sequence) position: , mismatch: 0, identity: 1.0

gtccagaagaatccaataataccagtacttt	CRISPR spacer
gtccagaagaatccaataataccagtacttt	Protospacer
*******************************

11. spacer 1.2|602|31|NC_004671|CRISPRCasFinder matches to MH830362 (Enterococcus faecalis plasmid p4, complete sequence) position: , mismatch: 0, identity: 1.0

gtccagaagaatccaataataccagtacttt	CRISPR spacer
gtccagaagaatccaataataccagtacttt	Protospacer
*******************************

12. spacer 1.2|602|31|NC_004671|CRISPRCasFinder matches to NZ_CP031028 (Enterococcus faecalis strain TY1 isolate flatfish plasmid pDEF-1, complete sequence) position: , mismatch: 0, identity: 1.0

gtccagaagaatccaataataccagtacttt	CRISPR spacer
gtccagaagaatccaataataccagtacttt	Protospacer
*******************************

13. spacer 1.2|602|31|NC_004671|CRISPRCasFinder matches to NZ_CP019514 (Enterococcus faecalis strain CLB21560 plasmid pB, complete sequence) position: , mismatch: 0, identity: 1.0

gtccagaagaatccaataataccagtacttt	CRISPR spacer
gtccagaagaatccaataataccagtacttt	Protospacer
*******************************

14. spacer 1.2|602|31|NC_004671|CRISPRCasFinder matches to NZ_CP036248 (Enterococcus faecalis R712 plasmid pR712_02, complete sequence) position: , mismatch: 0, identity: 1.0

gtccagaagaatccaataataccagtacttt	CRISPR spacer
gtccagaagaatccaataataccagtacttt	Protospacer
*******************************

15. spacer 1.2|602|31|NC_004671|CRISPRCasFinder matches to NZ_CP030046 (Enterococcus faecalis strain C54 plasmid pC54, complete sequence) position: , mismatch: 0, identity: 1.0

gtccagaagaatccaataataccagtacttt	CRISPR spacer
gtccagaagaatccaataataccagtacttt	Protospacer
*******************************

16. spacer 1.2|602|31|NC_004671|CRISPRCasFinder matches to NZ_CP028284 (Enterococcus faecalis strain FDAARGOS_324 plasmid unnamed2, complete sequence) position: , mismatch: 0, identity: 1.0

gtccagaagaatccaataataccagtacttt	CRISPR spacer
gtccagaagaatccaataataccagtacttt	Protospacer
*******************************

17. spacer 1.2|602|31|NC_004671|CRISPRCasFinder matches to NZ_KY513281 (Enterococcus faecalis strain 6742 plasmid p6742_2, complete sequence) position: , mismatch: 0, identity: 1.0

gtccagaagaatccaataataccagtacttt	CRISPR spacer
gtccagaagaatccaataataccagtacttt	Protospacer
*******************************

18. spacer 1.2|602|31|NC_004671|CRISPRCasFinder matches to NC_004671 (Enterococcus faecalis V583 plasmid pTEF2, complete sequence) position: , mismatch: 0, identity: 1.0

gtccagaagaatccaataataccagtacttt	CRISPR spacer
gtccagaagaatccaataataccagtacttt	Protospacer
*******************************

19. spacer 1.2|602|31|NC_004671|CRISPRCasFinder matches to NZ_CP015885 (Enterococcus faecalis strain sorialis plasmid Efsorialis-p2, complete sequence) position: , mismatch: 0, identity: 1.0

gtccagaagaatccaataataccagtacttt	CRISPR spacer
gtccagaagaatccaataataccagtacttt	Protospacer
*******************************

20. spacer 1.2|602|31|NC_004671|CRISPRCasFinder matches to NZ_CP040897 (Enterococcus faecalis strain HA-1 plasmid punnamed) position: , mismatch: 0, identity: 1.0

gtccagaagaatccaataataccagtacttt	CRISPR spacer
gtccagaagaatccaataataccagtacttt	Protospacer
*******************************

21. spacer 1.2|602|31|NC_004671|CRISPRCasFinder matches to NZ_CP046109 (Enterococcus faecalis strain 133170041-3 plasmid pAD1, complete sequence) position: , mismatch: 0, identity: 1.0

gtccagaagaatccaataataccagtacttt	CRISPR spacer
gtccagaagaatccaataataccagtacttt	Protospacer
*******************************

22. spacer 1.2|602|31|NC_004671|CRISPRCasFinder matches to NZ_CP049777 (Enterococcus faecalis strain ES-1 plasmid unnamed2, complete sequence) position: , mismatch: 0, identity: 1.0

gtccagaagaatccaataataccagtacttt	CRISPR spacer
gtccagaagaatccaataataccagtacttt	Protospacer
*******************************

23. spacer 1.2|602|31|NC_004671|CRISPRCasFinder matches to NZ_CP028837 (Enterococcus faecalis strain FC plasmid unnamed2, complete sequence) position: , mismatch: 0, identity: 1.0

gtccagaagaatccaataataccagtacttt	CRISPR spacer
gtccagaagaatccaataataccagtacttt	Protospacer
*******************************

24. spacer 1.2|602|31|NC_004671|CRISPRCasFinder matches to NC_011642 (Enterococcus faecalis plasmid pMG2200, complete sequence) position: , mismatch: 0, identity: 1.0

gtccagaagaatccaataataccagtacttt	CRISPR spacer
gtccagaagaatccaataataccagtacttt	Protospacer
*******************************

25. spacer 1.2|602|31|NC_004671|CRISPRCasFinder matches to LC499744 (Enterococcus faecalis S7316 plasmid pS7316optrA DNA, complete sequence) position: , mismatch: 0, identity: 1.0

gtccagaagaatccaataataccagtacttt	CRISPR spacer
gtccagaagaatccaataataccagtacttt	Protospacer
*******************************

26. spacer 1.2|602|31|NC_004671|CRISPRCasFinder matches to NZ_CP030043 (Enterococcus faecalis strain C25 plasmid pC25-1, complete sequence) position: , mismatch: 0, identity: 1.0

gtccagaagaatccaataataccagtacttt	CRISPR spacer
gtccagaagaatccaataataccagtacttt	Protospacer
*******************************

27. spacer 1.3|555|27|NC_004671|PILER-CR matches to NZ_CP030046 (Enterococcus faecalis strain C54 plasmid pC54, complete sequence) position: , mismatch: 0, identity: 1.0

ttcggataaacatgataaaatcggcgt	CRISPR spacer
ttcggataaacatgataaaatcggcgt	Protospacer
***************************

28. spacer 1.3|555|27|NC_004671|PILER-CR matches to NZ_CP028284 (Enterococcus faecalis strain FDAARGOS_324 plasmid unnamed2, complete sequence) position: , mismatch: 0, identity: 1.0

ttcggataaacatgataaaatcggcgt	CRISPR spacer
ttcggataaacatgataaaatcggcgt	Protospacer
***************************

29. spacer 1.3|555|27|NC_004671|PILER-CR matches to NC_004671 (Enterococcus faecalis V583 plasmid pTEF2, complete sequence) position: , mismatch: 0, identity: 1.0

ttcggataaacatgataaaatcggcgt	CRISPR spacer
ttcggataaacatgataaaatcggcgt	Protospacer
***************************

30. spacer 1.3|555|27|NC_004671|PILER-CR matches to NZ_CP015885 (Enterococcus faecalis strain sorialis plasmid Efsorialis-p2, complete sequence) position: , mismatch: 0, identity: 1.0

ttcggataaacatgataaaatcggcgt	CRISPR spacer
ttcggataaacatgataaaatcggcgt	Protospacer
***************************

31. spacer 1.3|555|27|NC_004671|PILER-CR matches to NZ_CP040897 (Enterococcus faecalis strain HA-1 plasmid punnamed) position: , mismatch: 0, identity: 1.0

ttcggataaacatgataaaatcggcgt	CRISPR spacer
ttcggataaacatgataaaatcggcgt	Protospacer
***************************

32. spacer 1.3|555|27|NC_004671|PILER-CR matches to NZ_CP046109 (Enterococcus faecalis strain 133170041-3 plasmid pAD1, complete sequence) position: , mismatch: 0, identity: 1.0

ttcggataaacatgataaaatcggcgt	CRISPR spacer
ttcggataaacatgataaaatcggcgt	Protospacer
***************************

33. spacer 1.3|555|27|NC_004671|PILER-CR matches to NZ_CP028837 (Enterococcus faecalis strain FC plasmid unnamed2, complete sequence) position: , mismatch: 0, identity: 1.0

ttcggataaacatgataaaatcggcgt	CRISPR spacer
ttcggataaacatgataaaatcggcgt	Protospacer
***************************

34. spacer 1.3|555|27|NC_004671|PILER-CR matches to NC_011642 (Enterococcus faecalis plasmid pMG2200, complete sequence) position: , mismatch: 0, identity: 1.0

ttcggataaacatgataaaatcggcgt	CRISPR spacer
ttcggataaacatgataaaatcggcgt	Protospacer
***************************

35. spacer 1.3|555|27|NC_004671|PILER-CR matches to NZ_CP030043 (Enterococcus faecalis strain C25 plasmid pC25-1, complete sequence) position: , mismatch: 0, identity: 1.0

ttcggataaacatgataaaatcggcgt	CRISPR spacer
ttcggataaacatgataaaatcggcgt	Protospacer
***************************

36. spacer 1.4|609|27|NC_004671|PILER-CR matches to CP002494 (Enterococcus faecalis 62 plasmid EF62pC, complete sequence) position: , mismatch: 0, identity: 1.0

tccagaagaatccaataataccagtac	CRISPR spacer
tccagaagaatccaataataccagtac	Protospacer
***************************

37. spacer 1.4|609|27|NC_004671|PILER-CR matches to MH830362 (Enterococcus faecalis plasmid p4, complete sequence) position: , mismatch: 0, identity: 1.0

tccagaagaatccaataataccagtac	CRISPR spacer
tccagaagaatccaataataccagtac	Protospacer
***************************

38. spacer 1.4|609|27|NC_004671|PILER-CR matches to NZ_CP031028 (Enterococcus faecalis strain TY1 isolate flatfish plasmid pDEF-1, complete sequence) position: , mismatch: 0, identity: 1.0

tccagaagaatccaataataccagtac	CRISPR spacer
tccagaagaatccaataataccagtac	Protospacer
***************************

39. spacer 1.4|609|27|NC_004671|PILER-CR matches to NZ_CP019514 (Enterococcus faecalis strain CLB21560 plasmid pB, complete sequence) position: , mismatch: 0, identity: 1.0

tccagaagaatccaataataccagtac	CRISPR spacer
tccagaagaatccaataataccagtac	Protospacer
***************************

40. spacer 1.4|609|27|NC_004671|PILER-CR matches to NZ_CP036248 (Enterococcus faecalis R712 plasmid pR712_02, complete sequence) position: , mismatch: 0, identity: 1.0

tccagaagaatccaataataccagtac	CRISPR spacer
tccagaagaatccaataataccagtac	Protospacer
***************************

41. spacer 1.4|609|27|NC_004671|PILER-CR matches to NZ_CP030046 (Enterococcus faecalis strain C54 plasmid pC54, complete sequence) position: , mismatch: 0, identity: 1.0

tccagaagaatccaataataccagtac	CRISPR spacer
tccagaagaatccaataataccagtac	Protospacer
***************************

42. spacer 1.4|609|27|NC_004671|PILER-CR matches to NZ_CP028284 (Enterococcus faecalis strain FDAARGOS_324 plasmid unnamed2, complete sequence) position: , mismatch: 0, identity: 1.0

tccagaagaatccaataataccagtac	CRISPR spacer
tccagaagaatccaataataccagtac	Protospacer
***************************

43. spacer 1.4|609|27|NC_004671|PILER-CR matches to NZ_KY513281 (Enterococcus faecalis strain 6742 plasmid p6742_2, complete sequence) position: , mismatch: 0, identity: 1.0

tccagaagaatccaataataccagtac	CRISPR spacer
tccagaagaatccaataataccagtac	Protospacer
***************************

44. spacer 1.4|609|27|NC_004671|PILER-CR matches to NC_004671 (Enterococcus faecalis V583 plasmid pTEF2, complete sequence) position: , mismatch: 0, identity: 1.0

tccagaagaatccaataataccagtac	CRISPR spacer
tccagaagaatccaataataccagtac	Protospacer
***************************

45. spacer 1.4|609|27|NC_004671|PILER-CR matches to NZ_CP015885 (Enterococcus faecalis strain sorialis plasmid Efsorialis-p2, complete sequence) position: , mismatch: 0, identity: 1.0

tccagaagaatccaataataccagtac	CRISPR spacer
tccagaagaatccaataataccagtac	Protospacer
***************************

46. spacer 1.4|609|27|NC_004671|PILER-CR matches to NZ_CP040897 (Enterococcus faecalis strain HA-1 plasmid punnamed) position: , mismatch: 0, identity: 1.0

tccagaagaatccaataataccagtac	CRISPR spacer
tccagaagaatccaataataccagtac	Protospacer
***************************

47. spacer 1.4|609|27|NC_004671|PILER-CR matches to NZ_CP046109 (Enterococcus faecalis strain 133170041-3 plasmid pAD1, complete sequence) position: , mismatch: 0, identity: 1.0

tccagaagaatccaataataccagtac	CRISPR spacer
tccagaagaatccaataataccagtac	Protospacer
***************************

48. spacer 1.4|609|27|NC_004671|PILER-CR matches to NZ_CP049777 (Enterococcus faecalis strain ES-1 plasmid unnamed2, complete sequence) position: , mismatch: 0, identity: 1.0

tccagaagaatccaataataccagtac	CRISPR spacer
tccagaagaatccaataataccagtac	Protospacer
***************************

49. spacer 1.4|609|27|NC_004671|PILER-CR matches to NZ_CP028837 (Enterococcus faecalis strain FC plasmid unnamed2, complete sequence) position: , mismatch: 0, identity: 1.0

tccagaagaatccaataataccagtac	CRISPR spacer
tccagaagaatccaataataccagtac	Protospacer
***************************

50. spacer 1.4|609|27|NC_004671|PILER-CR matches to NC_011642 (Enterococcus faecalis plasmid pMG2200, complete sequence) position: , mismatch: 0, identity: 1.0

tccagaagaatccaataataccagtac	CRISPR spacer
tccagaagaatccaataataccagtac	Protospacer
***************************

51. spacer 1.4|609|27|NC_004671|PILER-CR matches to LC499744 (Enterococcus faecalis S7316 plasmid pS7316optrA DNA, complete sequence) position: , mismatch: 0, identity: 1.0

tccagaagaatccaataataccagtac	CRISPR spacer
tccagaagaatccaataataccagtac	Protospacer
***************************

52. spacer 1.4|609|27|NC_004671|PILER-CR matches to NZ_CP030043 (Enterococcus faecalis strain C25 plasmid pC25-1, complete sequence) position: , mismatch: 0, identity: 1.0

tccagaagaatccaataataccagtac	CRISPR spacer
tccagaagaatccaataataccagtac	Protospacer
***************************

53. spacer 1.1|548|31|NC_004671|CRISPRCasFinder matches to CP002494 (Enterococcus faecalis 62 plasmid EF62pC, complete sequence) position: , mismatch: 1, identity: 0.968

cttcggataaacatgataaaatcggcgtttc	CRISPR spacer
cttcggataaacatgataaaatcggcatttc	Protospacer
**************************.****

54. spacer 1.1|548|31|NC_004671|CRISPRCasFinder matches to NZ_CP031028 (Enterococcus faecalis strain TY1 isolate flatfish plasmid pDEF-1, complete sequence) position: , mismatch: 1, identity: 0.968

cttcggataaacatgataaaatcggcgtttc	CRISPR spacer
cttcggataaacatgataaaatcggcatttc	Protospacer
**************************.****

55. spacer 1.1|548|31|NC_004671|CRISPRCasFinder matches to NZ_CP019514 (Enterococcus faecalis strain CLB21560 plasmid pB, complete sequence) position: , mismatch: 1, identity: 0.968

cttcggataaacatgataaaatcggcgtttc	CRISPR spacer
cttcggataaacatgataaaatcggcatttc	Protospacer
**************************.****

56. spacer 1.1|548|31|NC_004671|CRISPRCasFinder matches to NZ_CP036248 (Enterococcus faecalis R712 plasmid pR712_02, complete sequence) position: , mismatch: 1, identity: 0.968

cttcggataaacatgataaaatcggcgtttc	CRISPR spacer
cttcggataaacatgataaaatcggcatttc	Protospacer
**************************.****

57. spacer 1.2|602|31|NC_004671|CRISPRCasFinder matches to NC_013533 (Enterococcus faecalis plasmid pBEE99, complete sequence) position: , mismatch: 1, identity: 0.968

gtccagaagaatccaataataccagtacttt	CRISPR spacer
gtccagaagaatccaataataccaggacttt	Protospacer
************************* *****

58. spacer 1.3|555|27|NC_004671|PILER-CR matches to CP002494 (Enterococcus faecalis 62 plasmid EF62pC, complete sequence) position: , mismatch: 1, identity: 0.963

ttcggataaacatgataaaatcggcgt	CRISPR spacer
ttcggataaacatgataaaatcggcat	Protospacer
*************************.*

59. spacer 1.3|555|27|NC_004671|PILER-CR matches to MH830362 (Enterococcus faecalis plasmid p4, complete sequence) position: , mismatch: 1, identity: 0.963

ttcggataaacatgataaaatcggcgt	CRISPR spacer
ttcggataaacatgataaaatcagcgt	Protospacer
**********************.****

60. spacer 1.3|555|27|NC_004671|PILER-CR matches to NZ_CP031028 (Enterococcus faecalis strain TY1 isolate flatfish plasmid pDEF-1, complete sequence) position: , mismatch: 1, identity: 0.963

ttcggataaacatgataaaatcggcgt	CRISPR spacer
ttcggataaacatgataaaatcggcat	Protospacer
*************************.*

61. spacer 1.3|555|27|NC_004671|PILER-CR matches to NZ_CP019514 (Enterococcus faecalis strain CLB21560 plasmid pB, complete sequence) position: , mismatch: 1, identity: 0.963

ttcggataaacatgataaaatcggcgt	CRISPR spacer
ttcggataaacatgataaaatcggcat	Protospacer
*************************.*

62. spacer 1.3|555|27|NC_004671|PILER-CR matches to NZ_CP036248 (Enterococcus faecalis R712 plasmid pR712_02, complete sequence) position: , mismatch: 1, identity: 0.963

ttcggataaacatgataaaatcggcgt	CRISPR spacer
ttcggataaacatgataaaatcggcat	Protospacer
*************************.*

63. spacer 1.3|555|27|NC_004671|PILER-CR matches to NZ_CP049777 (Enterococcus faecalis strain ES-1 plasmid unnamed2, complete sequence) position: , mismatch: 1, identity: 0.963

ttcggataaacatgataaaatcggcgt	CRISPR spacer
ttcggataaacatgataaaatcagcgt	Protospacer
**********************.****

64. spacer 1.4|609|27|NC_004671|PILER-CR matches to NC_013533 (Enterococcus faecalis plasmid pBEE99, complete sequence) position: , mismatch: 1, identity: 0.963

tccagaagaatccaataataccagtac	CRISPR spacer
tccagaagaatccaataataccaggac	Protospacer
************************ **

65. spacer 1.1|548|31|NC_004671|CRISPRCasFinder matches to MH830362 (Enterococcus faecalis plasmid p4, complete sequence) position: , mismatch: 2, identity: 0.935

cttcggataaacatgataaaatcggcgtttc	CRISPR spacer
cttcggataaacatgataaaatcagcgttta	Protospacer
***********************.******

66. spacer 1.1|548|31|NC_004671|CRISPRCasFinder matches to NZ_CP049777 (Enterococcus faecalis strain ES-1 plasmid unnamed2, complete sequence) position: , mismatch: 2, identity: 0.935

cttcggataaacatgataaaatcggcgtttc	CRISPR spacer
cttcggataaacatgataaaatcagcgttta	Protospacer
***********************.******

67. spacer 1.1|548|31|NC_004671|CRISPRCasFinder matches to NZ_KY513281 (Enterococcus faecalis strain 6742 plasmid p6742_2, complete sequence) position: , mismatch: 2, identity: 0.935

cttcggataaacatgataaaatcggcgtttc	CRISPR spacer
cttcggataaacatgataaaatcaacgtttc	Protospacer
***********************..******

68. spacer 1.1|548|31|NC_004671|CRISPRCasFinder matches to NC_013533 (Enterococcus faecalis plasmid pBEE99, complete sequence) position: , mismatch: 2, identity: 0.935

cttcggataaacatgataaaatcggcgtttc	CRISPR spacer
cttcggataaacatgataaaatcaacgtttc	Protospacer
***********************..******

69. spacer 1.1|548|31|NC_004671|CRISPRCasFinder matches to LC499744 (Enterococcus faecalis S7316 plasmid pS7316optrA DNA, complete sequence) position: , mismatch: 2, identity: 0.935

cttcggataaacatgataaaatcggcgtttc	CRISPR spacer
cttcggataaacatgataaaatcaacgtttc	Protospacer
***********************..******

70. spacer 1.3|555|27|NC_004671|PILER-CR matches to NZ_KY513281 (Enterococcus faecalis strain 6742 plasmid p6742_2, complete sequence) position: , mismatch: 2, identity: 0.926

ttcggataaacatgataaaatcggcgt	CRISPR spacer
ttcggataaacatgataaaatcaacgt	Protospacer
**********************..***

71. spacer 1.3|555|27|NC_004671|PILER-CR matches to NC_013533 (Enterococcus faecalis plasmid pBEE99, complete sequence) position: , mismatch: 2, identity: 0.926

ttcggataaacatgataaaatcggcgt	CRISPR spacer
ttcggataaacatgataaaatcaacgt	Protospacer
**********************..***

72. spacer 1.3|555|27|NC_004671|PILER-CR matches to LC499744 (Enterococcus faecalis S7316 plasmid pS7316optrA DNA, complete sequence) position: , mismatch: 2, identity: 0.926

ttcggataaacatgataaaatcggcgt	CRISPR spacer
ttcggataaacatgataaaatcaacgt	Protospacer
**********************..***

73. spacer 1.4|609|27|NC_004671|PILER-CR matches to MT711976 (Streptomyces phage Coruscant, complete genome) position: , mismatch: 5, identity: 0.815

tccagaagaatccaataataccagtac	CRISPR spacer
tccagaagaagccaataaaaccactct	Protospacer
********** ******* **** * .

74. spacer 1.4|609|27|NC_004671|PILER-CR matches to NC_023573 (Staphylococcus phage phiSA012 DNA, complete genome) position: , mismatch: 5, identity: 0.815

tccagaagaatccaataataccagtac	CRISPR spacer
ttttgaagaatcctttaataccagtac	Protospacer
*.. *********  ************

75. spacer 1.4|609|27|NC_004671|PILER-CR matches to JQ660954 (Clostridium phage PhiS63, complete genome) position: , mismatch: 6, identity: 0.778

tccagaagaatccaataataccagtac	CRISPR spacer
aaacgaagaaaccaataatatcagtac	Protospacer
    ****** *********.******

76. spacer 1.2|602|31|NC_004671|CRISPRCasFinder matches to NC_023573 (Staphylococcus phage phiSA012 DNA, complete genome) position: , mismatch: 7, identity: 0.774

gtccagaagaatccaataataccagtacttt	CRISPR spacer
attttgaagaatcctttaataccagtactta	Protospacer
.*.. *********  **************

77. spacer 1.1|548|31|NC_004671|CRISPRCasFinder matches to NZ_CP022523 (Pseudoalteromonas sp. NC201 plasmid pNC201, complete sequence) position: , mismatch: 8, identity: 0.742

cttcggataaacatgataaaatcggcgtttc	CRISPR spacer
ccaccattaaaaatgataaaaacggcgtttt	Protospacer
*. * . **** ********* ********.

78. spacer 1.2|602|31|NC_004671|CRISPRCasFinder matches to MT711976 (Streptomyces phage Coruscant, complete genome) position: , mismatch: 8, identity: 0.742

gtccagaagaatccaataataccagtacttt	CRISPR spacer
atccagaagaagccaataaaaccactctgtg	Protospacer
.********** ******* **** * . *

79. spacer 1.2|602|31|NC_004671|CRISPRCasFinder matches to JQ660954 (Clostridium phage PhiS63, complete genome) position: , mismatch: 10, identity: 0.677

gtccagaagaatccaataataccagtacttt	CRISPR spacer
aaaacgaagaaaccaataatatcagtacaag	Protospacer
.    ****** *********.******

Prophage detection

Region	Region Position	Protein_number	Hit_taxonomy	Key_proteins	Att_site	Prophage annotation

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. NC_004669

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection

2. NC_004668

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Click the colored protein region to show detailed information

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection

3. NC_004671

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Click the colored protein region to show detailed information

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection