CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NC_003909	Bacillus cereus ATCC 10987, complete sequence	2 crisprs	DinG,cas3,csa3,WYL,c2c9_V-U4,c2c10_CAS-V-U3,cas14k,cas14j,RT,DEDDh	0	1	7	0
NC_005707	Bacillus cereus ATCC 10987 plasmid pBc10987, complete sequence	0 crisprs	RT,cas14j,csa3	0	0	0	0

Results visualization

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CRISPR-Cas detection and classification

Crispr_ID: NC_003909_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_003909_1

1919217-1919298

Orphan

Consensus_repeat	Method
AGTGAGTGATTACTCACTTTTGT	CRISPRCasFinder

1 spacers

The CRISPR arrays of NC_003909_1

>merge|NC_003909|1|1919217-1919298|CRISPRCasFinder
AGTGAGTGATTACTCACTTTTGTGTTGACTTTAATATTTGTGTTTCTTATAATAAGTTCAGTGAGTGATTACTCACTTTTTT

>NC_003909|1|1|1919217-1919298|CRISPRCasFinder
AGTGAGTGATTACTCACTTTTGT	GTTGACTTTAATATTTGTGTTTCTTATAATAAGTTC
AGTGAGTGATTACTCACTTTTTT

Protein	Signature genes	Signature genes Name	Protein_function
NC_003909.8\|WP_000737882.1\|1913074_1913470_+\|DUF2871-domain-containing-protein	unknown	unknown	gnl\|CDD\|378551
NC_003909.8\|WP_000108721.1\|1924665_1925631_-\|arsenic-resistance-protein	unknown	unknown	gnl\|CDD\|223869
NC_003909.8\|WP_000843007.1\|1914432_1915716_+\|aminopeptidase-P-family-protein	unknown	unknown	gnl\|CDD\|238520
NC_003909.8\|WP_000876191.1\|1909978_1911160_+\|NupC/NupG-family-nucleoside-CNT-transporter	unknown	unknown	gnl\|CDD\|224883
NC_003909.8\|WP_001983022.1\|1911196_1912498_+\|pyrimidine-nucleoside-phosphorylase	unknown	unknown	gnl\|CDD\|180387
NC_003909.8\|WP_000789787.1\|1914012_1914243_-\|DUF896-domain-containing-protein	unknown	unknown	gnl\|CDD\|167247
NC_003909.8\|WP_001128282.1\|1920955_1921837_+\|ATP-binding-cassette-domain-containing-protein	unknown	unknown	gnl\|CDD\|213197
NC_003909.8\|WP_000491565.1\|1921852_1922638_+\|ABC-transporter-permease-subunit	unknown	unknown	gnl\|CDD\|372253
NC_003909.8\|WP_000522523.1\|1925924_1926617_+\|FMN-dependent-NADH-azoreductase	unknown	unknown	gnl\|CDD\|184139
NC_003909.8\|WP_000354058.1\|1923291_1924539_+\|DUF4153-domain-containing-protein	unknown	unknown	unknown
NC_003909.8\|WP_000561063.1\|1913485_1913965_+\|cytochrome-c-biogenesis-protein-CcdC	unknown	unknown	gnl\|CDD\|377808
NC_003909.8\|WP_000750843.1\|1928299_1928719_+\|VOC-family-protein	unknown	unknown	gnl\|CDD\|319912
NC_003909.8\|WP_001284773.1\|1926857_1928216_+\|branched-chain-amino-acid-transport-system-II-carrier-protein	unknown	unknown	gnl\|CDD\|283235
NC_003909.8\|WP_000766743.1\|1916705_1918850_+\|DNA-topoisomerase-III	unknown	unknown	gnl\|CDD\|236078
NC_003909.8\|WP_000458515.1\|1915826_1916372_-\|hypothetical-protein	unknown	unknown	unknown
NC_003909.8\|WP_000358527.1\|1912531_1912927_+\|cytidine-deaminase	unknown	unknown	gnl\|CDD\|180142
NC_003909.8\|WP_000268447.1\|1920024_1920969_+\|ATP-binding-cassette-domain-containing-protein	unknown	unknown	gnl\|CDD\|213197
NC_003909.8\|WP_001017443.1\|1909204_1909876_+\|deoxyribose-phosphate-aldolase	unknown	unknown	gnl\|CDD\|234784
NC_003909.8\|WP_000070077.1\|1919314_1919971_+\|TetR/AcrR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|224228
NC_003909.8\|WP_000114295.1\|1929049_1930699_+\|copper-resistance-protein-CopC	unknown	unknown	gnl\|CDD\|224195

Protein	Function_ID	Function_description	E-value
NC_003909.8\|WP_000737882.1\|1913074_1913470_+\|DUF2871-domain-containing-protein	gnl\|CDD\|378551	pfam11070, DUF2871, Protein of unknown function (DUF2871). This family of proteins has no known function.	3.13268e-47
NC_003909.8\|WP_000108721.1\|1924665_1925631_-\|arsenic-resistance-protein	gnl\|CDD\|223869	COG0798, ACR3, Arsenite efflux pump ACR3 and related permeases [Inorganic ion transport and metabolism].	1.27031e-57
NC_003909.8\|WP_000843007.1\|1914432_1915716_+\|aminopeptidase-P-family-protein	gnl\|CDD\|238520	cd01087, Prolidase, Prolidase. E.C. 3.4.13.9. Also known as Xaa-Pro dipeptidase, X-Pro dipeptidase, proline dipeptidase., imidodipeptidase, peptidase D, gamma-peptidase. Catalyses hydrolysis of Xaa-Pro dipeptides; also acts on aminoacyl-hydroxyproline analogs. No action on Pro-Pro.	2.93355e-97
NC_003909.8\|WP_000876191.1\|1909978_1911160_+\|NupC/NupG-family-nucleoside-CNT-transporter	gnl\|CDD\|224883	COG1972, NupC, Nucleoside permease [Nucleotide transport and metabolism].	1.10494e-155
NC_003909.8\|WP_001983022.1\|1911196_1912498_+\|pyrimidine-nucleoside-phosphorylase	gnl\|CDD\|180387	PRK06078, PRK06078, pyrimidine-nucleoside phosphorylase; Reviewed.	0
NC_003909.8\|WP_001128282.1\|1920955_1921837_+\|ATP-binding-cassette-domain-containing-protein	gnl\|CDD\|213197	cd03230, ABC_DR_subfamily_A, ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A. This family of ATP-binding proteins belongs to a multi-subunit transporter involved in drug resistance (BcrA and DrrA), nodulation, lipid transport, and lantibiotic immunity. In bacteria and archaea, these transporters usually include an ATP-binding protein and one or two integral membrane proteins. Eukaryotic systems of the ABCA subfamily display ABC domains that are quite similar to this family. The ATP-binding domain shows the highest similarity between all members of the ABC transporter family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.	1.41669e-77
NC_003909.8\|WP_000114295.1\|1929049_1930699_+\|copper-resistance-protein-CopC	gnl\|CDD\|224195	COG1276, PcoD, Putative copper export protein [Inorganic ion transport and metabolism].	8.3369e-47
NC_003909.8\|WP_000491565.1\|1921852_1922638_+\|ABC-transporter-permease-subunit	gnl\|CDD\|372253	pfam12679, ABC2_membrane_2, ABC-2 family transporter protein. This family is related to the ABC-2 membrane transporter family.	0.000431349
NC_003909.8\|WP_000561063.1\|1913485_1913965_+\|cytochrome-c-biogenesis-protein-CcdC	gnl\|CDD\|377808	pfam07301, DUF1453, Protein of unknown function (DUF1453). This family consists of several hypothetical bacterial proteins of around 150 residues in length. The function of this family is unknown. Members of this family seem to be found exclusively in the Order Bacillales.	2.35227e-59
NC_003909.8\|WP_000789787.1\|1914012_1914243_-\|DUF896-domain-containing-protein	gnl\|CDD\|167247	PRK01631, PRK01631, hypothetical protein; Provisional.	3.70067e-35
NC_003909.8\|WP_000750843.1\|1928299_1928719_+\|VOC-family-protein	gnl\|CDD\|319912	cd07249, MMCE, Methylmalonyl-CoA epimerase (MMCE). MMCE, also called methylmalonyl-CoA racemase (EC 5.1.99.1) interconverts (2R)-methylmalonyl-CoA and (2S)-methylmalonyl-CoA. MMCE has been found in bacteria, archaea, and in animals. In eukaryotes, MMCE is an essential enzyme in a pathway that converts propionyl-CoA to succinyl-CoA, and is important in the breakdown of odd-chain length fatty acids, branched-chain amino acids, and other metabolites. In bacteria, MMCE participates in the reverse pathway for propionate fermentation, glyoxylate regeneration, and the biosynthesis of polyketide antibiotics. MMCE is closely related to glyoxalase I and type I extradiol dioxygenases.	3.64226e-47
NC_003909.8\|WP_001284773.1\|1926857_1928216_+\|branched-chain-amino-acid-transport-system-II-carrier-protein	gnl\|CDD\|283235	pfam05525, Branch_AA_trans, Branched-chain amino acid transport protein. This family consists of several bacterial branched-chain amino acid transport proteins which are responsible for the transport of leucine, isoleucine and valine via proton motive force.	2.82351e-175
NC_003909.8\|WP_000766743.1\|1916705_1918850_+\|DNA-topoisomerase-III	gnl\|CDD\|236078	PRK07726, PRK07726, DNA topoisomerase 3.	0
NC_003909.8\|WP_000522523.1\|1925924_1926617_+\|FMN-dependent-NADH-azoreductase	gnl\|CDD\|184139	PRK13555, PRK13555, FMN-dependent NADH-azoreductase.	7.9043e-142
NC_003909.8\|WP_000358527.1\|1912531_1912927_+\|cytidine-deaminase	gnl\|CDD\|180142	PRK05578, PRK05578, cytidine deaminase; Validated.	1.12357e-74
NC_003909.8\|WP_000268447.1\|1920024_1920969_+\|ATP-binding-cassette-domain-containing-protein	gnl\|CDD\|213197	cd03230, ABC_DR_subfamily_A, ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A. This family of ATP-binding proteins belongs to a multi-subunit transporter involved in drug resistance (BcrA and DrrA), nodulation, lipid transport, and lantibiotic immunity. In bacteria and archaea, these transporters usually include an ATP-binding protein and one or two integral membrane proteins. Eukaryotic systems of the ABCA subfamily display ABC domains that are quite similar to this family. The ATP-binding domain shows the highest similarity between all members of the ABC transporter family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.	2.4036e-77
NC_003909.8\|WP_001017443.1\|1909204_1909876_+\|deoxyribose-phosphate-aldolase	gnl\|CDD\|234784	PRK00507, PRK00507, deoxyribose-phosphate aldolase; Provisional.	1.30035e-125
NC_003909.8\|WP_000070077.1\|1919314_1919971_+\|TetR/AcrR-family-transcriptional-regulator	gnl\|CDD\|224228	COG1309, AcrR, Transcriptional regulator [Transcription].	3.91681e-19

>NC_003909.8|WP_000766743.1|1916705_1918850_+|DNA-topoisomerase-III
MKLIIAEKPDQGLALVSQFKYRRKDGYLEVEANELFPNGAYCTWAIGHLTQLCNPEHYHAEWKKWSLDTLPMIPERFQFEVTKSKYKQFNVVKQLLHNPQVTEIIHAGDAGREGELIVRNIINLCNVQKPMKRLWISSLTKQAIYQGFKNLLDESDTINTYYEAYTRSCADWVVGMNASRVFSILLKKKGMNDVFSAGRVQTPTLALIVKREKEIENFKSEPFWEVFATFNIEGKKYEGKWEKDSESRLKDPDMANKIAAFCQGKPAVVKEMKTERKEFQPPLLFNLSSLQATANKAFKFSPKKTLDITQALYQKGIVSYPRSDSNYVTQGEAATFPDILQKLSQFDEYKGLLPAPVESIMNNKRYVNEKKVTDHYAIIPTEQVTNPSKLSGDEKKIYDMIVRRLIAAHYEVAIFDYTTIVTLVDERAEFISKGKQQIQEGWRKVIFQDDKDDETILPIVAEGEEGKVVKVKVKEGKTQPPKRYTEGQLITLMKTAGKYLENEELEKVLKKTEGLGTEATRAGIITMLKDRKYIDVKKNQVYATDKGKVLITAIGDKILASPEMTAKWEQRLAEIGEGTASPATFMEQTKKLSAKIIEDAVEMSEKWDFTGLHVESIERKGSKFTTGKKVGSCKKCDGDVIDKSTFYGCSNYNTTQCDFTISKKILSKTISQKNMTKLLKGEKTDLIKGFKKGEKTFDAKLEWKDNKINFVFEN
>NC_003909.8|WP_000458515.1|1915826_1916372_-|hypothetical-protein
MFAYTLTALTLCCISIIITSYISKRNGTLMEYMVFIMSFSMSIGLSIGFYLGILFKGELLYSTLLAISISGCIGFLVGLRFHLYTALEGMFSGLMASMMGAMITEMLNAQQAHSILFISLLLTITITMSCMIQLLSETFSAFIQRRFLLLLSISVVIIVAVFVTFPDHTPPPSPGHDQHIH
>NC_003909.8|WP_000843007.1|1914432_1915716_+|aminopeptidase-P-family-protein
MKSTFFAQNRERLVNTLPDESITILFAGQAPHMSADAHYKFVPNRNFYYVTGIDEPNVIFMLKKVGGSVEETLFIEKSDPVMEKWVGKTVSNEEAEKISGIKKVVYLDSFEKTMSNVLFTENVKHLYLDLERREWNGTETKTLAFAKHVREQYPHVTIGNVYPNICELRVFKTEEEIEIMKEAIAVTKEGIYNVLKHAKADMMEYELEAQFDFTLKSSGIKHHAFNTILASGKNATVLHYEDNDAQIQNGDLVLLDLGAQKDYYNADISYTFPANGTFSSRQKQIYNIVLKALKETTEIIKPGLKFAALNEHAKKVLAEGCKAVGLIQEDEELSKYYYHGVSHFLGLDTHDVGTYKDRVLEEGMVITIEPGLYIEEESIGIRIEDDILVTKDGHENLSKDIIREVEEIEEFMRENNVHVKKDEVVTK
>NC_003909.8|WP_000789787.1|1914012_1914243_-|DUF896-domain-containing-protein
MKNILFRINELSKKEKVSGLTVDEKQEQQMLRQNYTQTFRGSLDSILLNTKIVDQNGHNVTPAALQDAQIRLKLSK
>NC_003909.8|WP_000561063.1|1913485_1913965_+|cytochrome-c-biogenesis-protein-CcdC
MIALLSSIVAVCMAVGVMFLRFKAAKKPVTKKKIILPPIFMSTGAMMYFLPEFRLTSLEIVEAITVGLIFSIFLIKTTKFEIRSEQIYMKPSKAFIFILVGLLAVRVALKSYLSQSIDLAELSGMFFLLAFAMIVSWRIAMYRSFTRLEKTIKRAGISK
>NC_003909.8|WP_000737882.1|1913074_1913470_+|DUF2871-domain-containing-protein
MKKLYNAAFSYLIIGLLSGVFAREYSKAQGIKGSTMLQLVHTHVLVLGFVFFLIALALCKVFHVQETKSFRAWFVVYNVGLLFTIATMLWRGLLQVNGTDFNGLSHMAGLGHVIISIGLVWFMILLKKSVK
>NC_003909.8|WP_000358527.1|1912531_1912927_+|cytidine-deaminase
MDKKKYIEEANKMLEKAYIPYSKFPVGAALVTKEGKIYTGCNIENASYGLCNCAERTAIFKAVSEGERDFSYLVITGETDGPISPCGACRQVIAEFCEPKMPVLLTNVKGDEKEVTVEQLLPGAFSIQDLK
>NC_003909.8|WP_001983022.1|1911196_1912498_+|pyrimidine-nucleoside-phosphorylase
MRMVDIIAKKRDGKELTTEEIKFFINGYTDGSIPDYQVSALAMAIFFKDMTDRERADLTMAMVESGETIDLSAIEGIKVDKHSTGGVGDTTTLVLGPLVAALDVPVAKMSGRGLGHTGGTIDKLEAVEGFHVEITKEQFIDIVNRDKVAVIGQTGNLTPADKKIYALRDVTGTVNSIPLIASSIMSKKIAAGADAIVLDVKTGAGAFMKTEEDAKELAHAMVRIGNNVGRQTMAVISDMSQPLGFAIGNALEVKEAIDTLKGEGPEDLTELVLVLGSQMVVLAKKANTLEEAREMLIEVMKNGKATEKFKEFLSNQGGDSSIVDNPEKMPQAKYVIDVPAKTSGVISNIVADEIGIAAMLLGAGRATKEDEIDLAVGLMLRKKVGDAVKEGEPFVTIYANRENVEDVKAKIYENISIAETAVAPKLVHTVITD
>NC_003909.8|WP_000876191.1|1909978_1911160_+|NupC/NupG-family-nucleoside-CNT-transporter
MKYLIGVLGLVLILGIAWLASNDRKKVKYRPIITMVILQFILGFLLLNTSVGNILISGIADGFGELLKYAADGVNFVFGGLVNQKEFSFFLSVLMPIVFISALIGILQHIKVLPIIVKSIGLALSKVNGMGKLESYNAVASAILGQSEVFISVKKQLGLLPEKRMYTLCASAMSTVSMSIVGSYMVLLKPQYVVTALVLNLFGGFIIASIINPYEVTEEEDMLEVQEEEKKTFFEVLGEYIIDGFKVAITVAAMLIGFVALIAFINAVFKGVIGISFQEILGYVFAPFAFIMGVPWHEAVNAGNIMATKLVSNEFVAMTDLAQGNFNFSDRTTAIISVFLVSFANFSSIGIIAGAVKSLNEKQGNVVARFGLKLLFGATLVSFLSATIVGLLF
>NC_003909.8|WP_001017443.1|1909204_1909876_+|deoxyribose-phosphate-aldolase
MNIAKLIDHTILKANTTKEDVMKVIEEAKEYKFASVCINPTWVKLAAEELAGHDVDVCTVIGFPLGASTTETKAFETKDAIAKGATEVDMVINVGALKDGDDELVEKDIYEVVQAAKGKALVKVIIETCLLTDEEKVRACELSVKAGADFVKTSTGFSTGGATAEDIALMRKTVGPNVGVKASGGVRTREDAEKMVAAGASRVGASASVAIVLNDAKGATDNY
>NC_003909.8|WP_000070077.1|1919314_1919971_+|TetR/AcrR-family-transcriptional-regulator
MSNPIFDKILAQGLIKGKTEKQQRIIETTIKLFAEKGYANTSTAEIAKVAGVSEGTIFKHYGKKDQLLLSVILPFVNDFFPNMAKELIEETMLEQTTSFEEFLRNLLKNRVAFITENKEIFRVIVKEIIYKEELKKELKPYFIKHVPVLFENIVEQFKEQGELIDLPADRILKMLFTLLAGFFVSRFVLMENHIISEEEIEDVVQFVMNGIKNKQSAE
>NC_003909.8|WP_000268447.1|1920024_1920969_+|ATP-binding-cassette-domain-containing-protein
MAVIQIDHLTKDYGHNRGVFDVSFKVEKGEVYGFLGPNGAGKTTTIRHIMGFSRPQVGKISVNGMNSWEKASEIQQDLGYLPGEIALPESLTGTEFIEMMAQLRGIEDMSHTNYLMKKFELDPSGSLKRMSLGMKRKLAIVTAFMHDPAVLILDEPTSALDPIMQKVFIEFIKEEKEKGKTILLSSHIFNEIDATCDKISIIKDGRLISTFVADDLRHNAEKTFKLEFDSKEVFERFKNEVPSHKKIKVISLKSHKNQVELRVNDADTNDFIAFISDYDLKFCSEIKFTLEDYFMKFYDRNSKNEGGGEQSATN
>NC_003909.8|WP_001128282.1|1920955_1921837_+|ATP-binding-cassette-domain-containing-protein
MPLIEINNMTKDYGDGRGIFDVSLSIEKGEVFGFVGTNGAGKTTTIRHMMGFLKPQSGNATINGMDCWKDSAEIKKMIGYIPGEIAFPDAPTGTEFLKRQAELLGLKDMSYAESIIKKLQLDPTANLKRMSKGMKQKTAIVAALMADPEILIFDEPTTGLDPLMRAEFISILDEQKKKGKTIFMSSHMFDEVEHTCDKVALIKDGKIIAVKSTKEIKYNQEKAYKIEFNSHEDYKLFLAEPFDFTEKRESQNQVIVNVHDRQINTLLKTLKGYNIKFITEIKYTLEKYFNSQY
>NC_003909.8|WP_000491565.1|1921852_1922638_+|ABC-transporter-permease-subunit
MFSKAIFKQTLKANFKLWIIFTVITSAMLAVMIAVFEPTTLTGMTDMVKGTPLADMMKNTTFLGMLASTFYSMHGVLLPVIFIMMTANSLIASQVDRGSMAYLLSTPTKRSTVVRTQALYLITSLIMMFVIVTGVGLAAIQIFQGNVDINISDFIMLNVGLFLLMFATSAISFFFSCLFNLSKNSLALGAGIPVAFFLFQLMGQVSKSLEKMKYLSLNTLFDTSAILNGDSVAIPFIILIGVGIILYGLGMRVFQQKDLPL
>NC_003909.8|WP_000354058.1|1923291_1924539_+|DUF4153-domain-containing-protein
MDINNLIIENMDNPHELERMYRKDPRAFRKSFSQAWDENLDSQVLAAWYERLHFKETANKEKVSLFQKGFLFMGMLAILAGLSTRIIFHFVEQEAIAPINLAFGVIPFIAAYFVYNNTPKKSIIYSLAALFLIAGLYLNMLPLNYKDSSILAYLHLPILLWVLLGLAFTGNEYSKGSTRLAYIKFNLEYCLLYASMAVSGMILAIFTMRLFSFVDLDIGEFYFSNVVLFGAAALAVVAAYLVSLNLKLAKNITPYISKIFSPLVLITLFIYLITVIWVGKNPFLDRNFLMAFNGILLGVLAVTIFSIVESDSDEKKSISDYINFALIVLALIIDTVALSAIVFRLSSYGITPNRLAVLGVNILIWANLIWIMFSYMRFLQNKSGPTAIQDAVTKYLPIYGLWAAFVIFTFPLIFN
>NC_003909.8|WP_000108721.1|1924665_1925631_-|arsenic-resistance-protein
MSTVEKIQTFIILFAVTCGIVLGQFHLIHMYSEQFIVPFLFFMLYGLFLSIPLKEIKNGFRNLKFAGTSLTINFLWTPLLAWGLGALFLSDHPALWVGFIMLMVTPCTDWYLIFTEIAKGNVALSTAILPVNLILQVLLLPIYLFLFAGVMKTVAVSVLVESIVIVIVLPFLLAHATKFIMNKLKKAETLENKLIPFFSSAQIVFLSLAIVAMFASQGKYLLQNMNVVLLLLIPVLLFFIINFVLGQFIGRVMRLSYKDTVSLNLTTLARNSPVALAIAVTAFPNEPLIALALVIGPLIELPVLACVSQVLLLIKKKKQYT
>NC_003909.8|WP_000522523.1|1925924_1926617_+|FMN-dependent-NADH-azoreductase
MGLFSSLFGKKEENTKVEGNKTMSKVLFVKANDRPAEQAVSSKMYETFVSTYKEANPNTEITELDLFALDLPYYGNIAISGGYKRSQGMELTAEEEKAVATVDQYLNQFLEADKVVFAFPLWNFTVPAPLITYISYLSQAGKTFKYTANGPEGLAGGKKVVVLGARGSDYSSEQMAPMEMAVNYVTTVLGFWGITNPETVVIEGHNQYPDRSQQIVEEGLEKVKKVAAKF
>NC_003909.8|WP_001284773.1|1926857_1928216_+|branched-chain-amino-acid-transport-system-II-carrier-protein
MANKVPFSFIVVIGLMLFALFFGAGNLIFPAMLGQSAGENVWIANAGFLVTGVGLPLLGVLAFGFSGKDDLQSLASRAHPVFGIVFTTVLYLAIGPLFAIPRTGNVSYEIGLKPFMPEGLGSTPLILFTIVFFSITCFFSLNPAKIVDIVGKILTPIKLTFIGILVIVAFIHPIGEMQAPVEAYTSHAFFKGFQEGYLTMDTLASFVFGIIIINAIKEKGAKTKTQIMVVCAKATIIAASILAIIYTALSYMGASSVAKLGHLENGGEVLAKVSNYYFGSYGGVLLGLMITVACLTTSVGLVSACSSFFHKLFPNVPYKAIAITLCIFSAIVANVGLTQLIAVSVPVLTAIYPLAIVLIFLTFFHSLFKGRAEVYQVSLTVTFIISLFDGLSAAGVNVEVVSQVFTKFLPMQEVGLGWIFPAIIGGFIGYGISVLKVKNQIQPAASANKKIG
>NC_003909.8|WP_000750843.1|1928299_1928719_+|VOC-family-protein
MKKTIDHIGIAVRDIDSTIRFYEKVLSGTLIDRYVSEAPGVESEVAILEVEGDRIELLAPTNNTTSPIARFIKQKGKGVHHVAYRVDDLDVALEELKEQGIRTLEHTLRINKHGRRLIYLNPADTEGTIIEYCDYPEEK
>NC_003909.8|WP_000114295.1|1929049_1930699_+|copper-resistance-protein-CopC
MSVKVMKRLGTLLFIVCVLIILIPKSASAHAYVVKSNPTENETLKKAPSVVKIEFDEDIQISSFNTLYVRDTSGKRVDLKDAHIDKKNKKLLEAGLEENLKNGLYSIQWKVISADGHPIQGVIPFRIGLAEAGADDIQVEEMGYVPQIDMIMERGILYTSFSLFIGVLFFNLIMYKGNATSVRSRSKNIIWISLLGIFISLLFNLPLQAKINADVSWLEAFNPLLLKETLQLSVFSYVWVTQMALISLLIIVTYFAMRREKLSSFKVWSIPIVLFIGILVMKAFNSHAYGLKFKDIAVVMDFLHLFAASLWIGGLSSIILLLRKEDNKWNMYWDMIKRFSPWATCAVIVILITGLFNSTFFIPTIHSLFDTKYGLALLAKVLLFIFMGILGIIHYVKGRMRAEQELGATVKVEFIIGIIIFVIVAFMTNVQTPPMPPTGPFTESKQLDNGYEMTLNVSPNKVGQNTFHITLKDENGQPVPDMEQIILTTQSLDMNMGKGSFKVSAVSPGEYEAEGMYINMTGNWNIQVHGLTKSLDSFDTDYRFIVGGR

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Crispr_ID: NC_003909_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_003909_2

5046910-5047101

Orphan

Consensus_repeat	Method
TCNTCNTCNTCTTCGTCT	CRT

4 spacers

The CRISPR arrays of NC_003909_2

>merge|NC_003909|2|5046910-5047101|CRT
TCTTCCTCTTCTTCTTCTTCAGTTTCATCATACTCAAGTTCTTCTTCAGCGAAGTCATCTTCATCTTCGTCTAAATCATCAAGATCATCGTCGTCTCCGTCTTCGTCTTCAAGAACCTTGTCCAAATCTTCTACATCATCATCTTCGTCTTCATTTCCATCTACATCATCAAAGTCATCTTCATCTTCGTCA

>NC_003909|2|1|5046910-5047101|CRT
TCTTCCTCTTCTTCTTCT	TCAGTTTCATCATACTCAAGTTCTTCTTCAGCGAAG
TCATCTTCATCTTCGTCT	AAATCATCAAGATCATCG
TCGTCTCCGTCTTCGTCT	TCAAGAACCTTGTCCAAATCTTCT
ACATCATCATCTTCGTCT	TCATTTCCATCTACATCATCAAAG
TCATCTTCATCTTCGTCA

Protein	Signature genes	Signature genes Name	Protein_function
NC_003909.8\|WP_000912422.1\|5044482_5045007_+\|DUF2529-domain-containing-protein	unknown	unknown	gnl\|CDD\|378487
NC_003909.8\|WP_001086788.1\|5052827_5054939_-\|(Fe-S)-binding-protein	unknown	unknown	gnl\|CDD\|223325
NC_003909.8\|WP_000398594.1\|5043912_5044281_-\|sporulation-initiation-phosphotransferase-Spo0F	unknown	unknown	gnl\|CDD\|381105
NC_003909.8\|WP_000280865.1\|5037256_5037844_-\|thymidine-kinase	unknown	unknown	gnl\|CDD\|235272
NC_003909.8\|WP_000609937.1\|5057553_5060232_+\|DUF4084-domain-containing-protein	unknown	unknown	gnl\|CDD\|372562
NC_003909.8\|WP_000238604.1\|5047577_5048207_-\|TetR/AcrR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|224228
NC_003909.8\|WP_000734728.1\|5060249_5060396_-\|quorum-sensing-peptide-PapR	unknown	unknown	gnl\|CDD\|368687
NC_003909.8\|WP_001011168.1\|5049432_5050563_-\|acyl-CoA-dehydrogenase	unknown	unknown	gnl\|CDD\|173847
NC_003909.8\|WP_000887065.1\|5035920_5036988_-\|peptide-chain-release-factor-1	unknown	unknown	gnl\|CDD\|234801
NC_003909.8\|WP_000116032.1\|5050635_5051487_-\|3-hydroxybutyryl-CoA-dehydrogenase	unknown	unknown	gnl\|CDD\|180269
NC_003909.8\|WP_000170453.1\|5045037_5046645_-\|CTP-synthase	unknown	unknown	gnl\|CDD\|235437
NC_003909.8\|WP_000047988.1\|5051536_5052718_-\|acetyl-CoA-C-acetyltransferase	unknown	unknown	gnl\|CDD\|181311
NC_003909.8\|WP_000545534.1\|5048271_5049411_-\|acyl-CoA-dehydrogenase-AcdA	unknown	unknown	gnl\|CDD\|173847
NC_003909.8\|WP_000442334.1\|5040146_5041112_-\|class-II-fructose-bisphosphatase	unknown	unknown	gnl\|CDD\|236536
NC_003909.8\|WP_000413260.1\|5041223_5042513_-\|UDP-N-acetylglucosamine-1-carboxyvinyltransferase	unknown	unknown	gnl\|CDD\|183779
NC_003909.8\|WP_000643437.1\|5037952_5038198_-\|type-B-50S-ribosomal-protein-L31	unknown	unknown	gnl\|CDD\|234969
NC_003909.8\|WP_001053898.1\|5038596_5039868_-\|transcription-termination-factor-Rho	unknown	unknown	gnl\|CDD\|236490
NC_003909.8\|WP_001131850.1\|5042844_5043702_-\|fructose-bisphosphate-aldolase	unknown	unknown	gnl\|CDD\|169068
NC_003909.8\|WP_000465820.1\|5055245_5056439_+\|cardiolipin-synthase	unknown	unknown	gnl\|CDD\|234967
NC_003909.8\|WP_000605888.1\|5056471_5057425_+\|UV-DNA-damage-repair-endonuclease-UvsE	unknown	unknown	gnl\|CDD\|235029

Protein	Function_ID	Function_description	E-value
NC_003909.8\|WP_000912422.1\|5044482_5045007_+\|DUF2529-domain-containing-protein	gnl\|CDD\|378487	pfam10740, DUF2529, Domain of unknown function (DUF2529). This domain is conserved in the Bacillales. The function is not known, but given this domains relationship to the SIS domain it may carry out a sugar isomerase reaction. Several members are annotated as being YWJG, a protein expressed downstream of pyrG, a gene encoding for cytidine triphosphate synthetase.	3.86421e-75
NC_003909.8\|WP_001086788.1\|5052827_5054939_-\|(Fe-S)-binding-protein	gnl\|CDD\|223325	COG0247, GlpC, Fe-S oxidoreductase [Energy production and conversion].	3.98861e-94
NC_003909.8\|WP_000398594.1\|5043912_5044281_-\|sporulation-initiation-phosphotransferase-Spo0F	gnl\|CDD\|381105	cd17553, REC_Spo0F-like, phosphoacceptor receiver (REC) domain of Spo0F and similar domains. Spo0F, a stand-alone response regulator containing only a REC domain with no output/effector domain, controls sporulation in Bacillus subtilis through the exchange of a phosphoryl group. Bacillus subtilis forms spores when conditions for growth become unfavorable. The initiation of sporulation is controlled by a phosphorelay (an expanded version of the two-component system) that consists of four main components: a histidine kinase (KinA), a secondary messenger (Spo0F), a phosphotransferase (Spo0B), and a transcription factor (Spo0A). REC domains function as phosphorylation-mediated switches within response regulators, but some also transfer phosphoryl groups in multistep phosphorelays.	2.77706e-64
NC_003909.8\|WP_000280865.1\|5037256_5037844_-\|thymidine-kinase	gnl\|CDD\|235272	PRK04296, PRK04296, thymidine kinase; Provisional.	5.22616e-103
NC_003909.8\|WP_000609937.1\|5057553_5060232_+\|DUF4084-domain-containing-protein	gnl\|CDD\|372562	pfam13321, DUF4084, Domain of unknown function (DUF4084). This family of Firmicute proteins is frequently associated with the EAL, GGDEF and PAS families, pfam00563, pfam00990, and pfam00989. The exact function is not known.	0
NC_003909.8\|WP_000238604.1\|5047577_5048207_-\|TetR/AcrR-family-transcriptional-regulator	gnl\|CDD\|224228	COG1309, AcrR, Transcriptional regulator [Transcription].	8.86765e-14
NC_003909.8\|WP_000734728.1\|5060249_5060396_-\|quorum-sensing-peptide-PapR	gnl\|CDD\|368687	pfam05968, Bacillus_PapR, Bacillus PapR protein. This family consists of the Bacillus species specific PapR protein. The papR gene belongs to the PlcR regulon and is located 70 bp downstream from plcR. It encodes a 48-amino-acid peptide. Disruption of the papR gene abolishes expression of the PlcR regulon, resulting in a large decrease in haemolysis and virulence in insect larvae. A processed form of PapR activates the PlcR regulon by allowing PlcR to bind to its DNA target. This activating mechanism is strain specific.	9.78729e-07
NC_003909.8\|WP_001011168.1\|5049432_5050563_-\|acyl-CoA-dehydrogenase	gnl\|CDD\|173847	cd01158, SCAD_SBCAD, Short chain acyl-CoA dehydrogenases and eukaryotic short/branched chain acyl-CoA dehydrogenases. Short chain acyl-CoA dehydrogenase (SCAD). SCAD is a mitochondrial beta-oxidation enzyme. It catalyzes the alpha,beta dehydrogenation of the corresponding trans-enoyl-CoA by FAD, which becomes reduced. The reduced form of SCAD is reoxidized in the oxidative half-reaction by electron-transferring flavoprotein (ETF), from which the electrons are transferred to the mitochondrial respiratory chain coupled with ATP synthesis. This subgroup also contains the eukaryotic short/branched chain acyl-CoA dehydrogenase(SBCAD), the bacterial butyryl-CoA dehydorgenase(BCAD) and 2-methylbutyryl-CoA dehydrogenase, which is involved in isoleucine catabolism. These enzymes are homotetramers.	0
NC_003909.8\|WP_000887065.1\|5035920_5036988_-\|peptide-chain-release-factor-1	gnl\|CDD\|234801	PRK00591, prfA, peptide chain release factor 1; Validated.	0
NC_003909.8\|WP_000116032.1\|5050635_5051487_-\|3-hydroxybutyryl-CoA-dehydrogenase	gnl\|CDD\|180269	PRK05808, PRK05808, 3-hydroxybutyryl-CoA dehydrogenase; Validated.	0
NC_003909.8\|WP_000170453.1\|5045037_5046645_-\|CTP-synthase	gnl\|CDD\|235437	PRK05380, pyrG, CTP synthetase; Validated.	0
NC_003909.8\|WP_000047988.1\|5051536_5052718_-\|acetyl-CoA-C-acetyltransferase	gnl\|CDD\|181311	PRK08235, PRK08235, acetyl-CoA C-acetyltransferase.	0
NC_003909.8\|WP_000545534.1\|5048271_5049411_-\|acyl-CoA-dehydrogenase-AcdA	gnl\|CDD\|173847	cd01158, SCAD_SBCAD, Short chain acyl-CoA dehydrogenases and eukaryotic short/branched chain acyl-CoA dehydrogenases. Short chain acyl-CoA dehydrogenase (SCAD). SCAD is a mitochondrial beta-oxidation enzyme. It catalyzes the alpha,beta dehydrogenation of the corresponding trans-enoyl-CoA by FAD, which becomes reduced. The reduced form of SCAD is reoxidized in the oxidative half-reaction by electron-transferring flavoprotein (ETF), from which the electrons are transferred to the mitochondrial respiratory chain coupled with ATP synthesis. This subgroup also contains the eukaryotic short/branched chain acyl-CoA dehydrogenase(SBCAD), the bacterial butyryl-CoA dehydorgenase(BCAD) and 2-methylbutyryl-CoA dehydrogenase, which is involved in isoleucine catabolism. These enzymes are homotetramers.	0
NC_003909.8\|WP_000442334.1\|5040146_5041112_-\|class-II-fructose-bisphosphatase	gnl\|CDD\|236536	PRK09479, glpX, fructose 1,6-bisphosphatase II; Reviewed.	0
NC_003909.8\|WP_000413260.1\|5041223_5042513_-\|UDP-N-acetylglucosamine-1-carboxyvinyltransferase	gnl\|CDD\|183779	PRK12830, PRK12830, UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Reviewed.	0
NC_003909.8\|WP_000643437.1\|5037952_5038198_-\|type-B-50S-ribosomal-protein-L31	gnl\|CDD\|234969	PRK01678, rpmE2, type B 50S ribosomal protein L31.	3.07711e-51
NC_003909.8\|WP_001053898.1\|5038596_5039868_-\|transcription-termination-factor-Rho	gnl\|CDD\|236490	PRK09376, rho, transcription termination factor Rho; Provisional.	0
NC_003909.8\|WP_001131850.1\|5042844_5043702_-\|fructose-bisphosphate-aldolase	gnl\|CDD\|169068	PRK07709, PRK07709, fructose-bisphosphate aldolase; Provisional.	0
NC_003909.8\|WP_000465820.1\|5055245_5056439_+\|cardiolipin-synthase	gnl\|CDD\|234967	PRK01642, cls, cardiolipin synthetase; Reviewed.	1.14281e-106
NC_003909.8\|WP_000605888.1\|5056471_5057425_+\|UV-DNA-damage-repair-endonuclease-UvsE	gnl\|CDD\|235029	PRK02308, uvsE, putative UV damage endonuclease; Provisional.	8.60034e-166

>NC_003909.8|WP_000170453.1|5045037_5046645_-|CTP-synthase
MTKYIFVTGGVVSSLGKGITAASLGRLLKNRGLNVTIQKFDPYINVDPGTMSPYQHGEVFVTDDGAETDLDLGHYERFIDINLNKYSNVTTGKIYSSVLQKERRGEYLGGTVQVIPHITNEIKERVYRSGRETNADVVITEIGGTVGDIESLPFLEAIRQIKSDIGRDNVMYIHCTLIPYLKAAGEMKTKPTQHSVKELRSLGIQPNIIVVRTEMPVSQDMKDKLALFCDIDTKAVIEARDADTLYAVPLSLQEQNMDQIVCDHLKLDNPAADMTEWTALVEKVRNLSKKTKIALVGKYVELQDAYISVVEALRHAGYSFDTDVEVKWVNAEHVTAENVQELVGDTDGILVPGGFGDRGVEGKIVAIQYARENKVPFLGICLGMQLASIEFARNVLGLEGANSSEINPDTPYAIIDLLPEQKDVEDLGGTLRLGLYPCKLAEETNAYNAYNEPVVYERHRHRYEFNNQFRPDMEKAGFVFSGTSPDGRLVEIVELKDHPWFVAAQFHPELVSRPNRPQPLFHDFVRASITNKESK
>NC_003909.8|WP_000912422.1|5044482_5045007_+|DUF2529-domain-containing-protein
MLKIFSTQLSGYFSRVSQKEEMNIEDSARLLAQALVGEGFIYLHGTNEMEGVVAEALFGAEPMKQAKRLFENGKEVEVTSADRVLLISRFSTDEEVVAIAKKLQADGHSIVGISAIQEGNESLEQYTDVHIDTKLLKGLIPDDEGNRYGFPSLMIALFAYHGIKFTIDEMLNEY
>NC_003909.8|WP_000398594.1|5043912_5044281_-|sporulation-initiation-phosphotransferase-Spo0F
MEGKILIVDDQYGIRVLLHEVFQKEGYQTFQAANGFQALDIVKKDNPDLVVLDMKIPGMDGIEILKHVKEIDESIKVILMTAYGELDMIQEAKDLGALMHFAKPFDIDEIRQAVRNELAVEA
>NC_003909.8|WP_001131850.1|5042844_5043702_-|fructose-bisphosphate-aldolase
MPLVSMKEMLNKALEGKYAVGQFNMNNLEWTQAILAAAEEEKSPVILGVSEGAARHMTGFKTVVAMVKALIEEMNITVPVAIHLDHGSSFEKCKEAIDAGFTSVMIDASHHPFEENVETTKKVVEYAHARNVSVEAELGTVGGQEDDVIAEGVIYADPAECKHLVEATGIDCLAPALGSVHGPYKGEPNLGFAEMEQVRDFTGVPLVLHGGTGIPTADIEKAISLGTSKINVNTENQIEFTKAVREVLNKDQEVYDPRKFIGPGRDAIKATVIGKIREFGSNGKA
>NC_003909.8|WP_000413260.1|5041223_5042513_-|UDP-N-acetylglucosamine-1-carboxyvinyltransferase
MEKLLIEGGRALNGTIRVSGAKNSAVALIPATILADTPVTIGGVPNISDVKMLGDLLEEIGGRVTYGQEEEMVVDPSNMVAMPLPNGKVKKLRASYYLMGAMLGRFKKAVIGLPGGCHLGPRPIDQHIKGFEALGAHVTNEQGAIYLRADELRGARIYLDVVSVGATINIMLAAVRAKGRTVIENAAKEPEIIDVATLLTSMGARIKGAGTDVIRIDGVDSLHGCHHTIIPDRIEAGTYMILGAASGGEVTVDNVIPQHLESVTAKLREAGVQVETNDDQITVNGDRRLKVVDIKTLVYPGFPTDLQQPFTTLLTKAHGTGVVTDTIYGARFKHIDELRRMNAQIKVEGRSAIVTGPVLLQGAKVKASDLRAGAALVIAGLMADGITEVTGLEHIDRGYENIVDKLKGLGANIWREQMTKQEIEEMKNA
>NC_003909.8|WP_000442334.1|5040146_5041112_-|class-II-fructose-bisphosphatase
MERSLSMELVRVTEAAALSSARWMGRGKKDEADGAATSAMRDVFDTIPMKGTVVIGEGEMDEAPMLYIGEKLGTGYGPRVDVAVDPLEGTNIVAAGGWNALAVIAIADHGNLLHAPDMYMDKIAVGPEAVGAVDIDAPIIDNLRAVAKAKNKDIEDVVATVLNRPRHQAIIEEIRKAGARIKLINDGDVAGAINTAFDRTGVDILFGSGGAPEGVLAAVALKCLGGEIHGKLLPQNEAELARCKKMGIDDINRILRMEDLVKGDDAIFAATGVTDGELLRGVQFKGSVGTTQSLVMRAKSGTVRFVDGRHSLNKKPNLVIK
>NC_003909.8|WP_001053898.1|5038596_5039868_-|transcription-termination-factor-Rho
MNLSIAALENMKLKELYELAKEFKISYYSKLTKKELIFAILKARAEKEGFFFMEGVLEIIQSEGFGFLRPINYSPSSEDIYISASQIRRFDLRNGDKVSGKVRPPKENERYFGLLQVEAVNGDDPESAKERVHFPALTPLYPDRQMKLETEPKKLPTRIMDLIAPVGFGQRGLIVAPPKAGKTSLLKEIAHSVTTNHPEAELIVLLIDERPEEVTDIERSVKGDVVSSTFDEVPENHIKVAELVLERAMRLVEHKKDVIILMDSITRLARAYNLVIPPSGRTLSGGIDPAAFHRPKRFFGAARNIEEGGSLTILATALVDTGSRMDDVIYEEFKGTGNMELHLDRSLAERRIFPAIDIRRSGTRKEDLLIPKEHLDKLWGIRKTMRDTPDFVEGFLRKLRQTKTNEEFLQNIVADSKRYVTTK
>NC_003909.8|WP_000643437.1|5037952_5038198_-|type-B-50S-ribosomal-protein-L31
MKAGIHPDYKKVVFMDTNTGFKFLSGSTRGSNETVEWEDGNTYPLLKVEISSDSHPFYTGRQKFATADGRVDRFNKKYGLK
>NC_003909.8|WP_000280865.1|5037256_5037844_-|thymidine-kinase
MYLINQNGWIEVICGSMFSGKSEELIRRVRRTQFAKQHAIVFKPCIDNRYSEEDVVSHNGLKVKAVPVSASKDIFEHITEEMDVIAIDEVQFFDGDIVEVVQVLANRGYRVIVAGLDQDFRGLPFGQVPQLMAIAEHVTKLQAVCSACGSPASRTQRLIDGEPAAFDDPIILVGASESYEPRCRHXHAVPTNKDK
>NC_003909.8|WP_000887065.1|5035920_5036988_-|peptide-chain-release-factor-1
MLDRLQAVENRYEKLNELLSDPAIISDSNKLREYSKEQSDIQETVEVYREYKDVREQLKDAKAMLEDKLDAEMREMVKEEVSELESQEKTLSERLKILLVPKDPNDDKNVIVEVRGAAGGDEAALFAGDLYRMYSRYAEVQGWKTEIIEASYTELGGYKEIIFMINGKGAFAKLKFENGAHRVQRVPETESGGRIHTSTATVAVLPEAEEVEIDIHEKDVRVDTFASSGPGGQSVNTTMSAVRLTHLPTGVVVSCQDEKSQIKNKEKAMKVLRARVYDKFRQEAQAEYDQNRKQAVGTGDRSERIRTYNFPQNRVTDHRIGLTIQKLDQILQGKLDDFINALVMEDQAQRMEAAE
>NC_003909.8|WP_000238604.1|5047577_5048207_-|TetR/AcrR-family-transcriptional-regulator
MVKHNVHASVKDEKLVALRREQMIKGAVQLFKQKGFPRTTTREIAKAAGFSIGTLYEYIRTKDDVLYLVCDSIYEHVKERLEEVVCTEKGSVESLKIAITNYFKVMDELQEEVLIMYQEVRFLPKESLPYVLEKEFQMVGMFENILEQCTENGTFTLNKKEIQLLAHNIFIQGQMWGFRRWALQKLYTLEEYTDMQIRYVLQGAHMLPK
>NC_003909.8|WP_000545534.1|5048271_5049411_-|acyl-CoA-dehydrogenase-AcdA
MHFKLSEEHEMIRKMVRDFAKNEVAPTAAERDEEERFDRALFDQMAELGLTGIPWPEEYGGIGSDYLAYVIAIEELSRVCASTGVTLSAHTSLAGWPIFKFGTEEQKQTFLRPMAEGKKIGAYGLTEPGSGSDAGGMKTIAKRDGDHYVLNGSKIFITNGGIADIYVVFALTDPESKQRGTSAFIVESDTPGFSVGKKESKLGIRSSPTTEIMFEDCRIPVENLLGEEGQGFKIAMQTLDGGRNGIAAQAVGIAQGALDASVEYARERHQFGKPIAVQQGIGFKLADMATDVEAARLLTYQAAWLESEGLPYGKESAMSKVFAGDAAMKVTTEAVQVFGGYGYTKDYPVERYMRDAKITQIYEGTQEIQRLVISRMLTK
>NC_003909.8|WP_001011168.1|5049432_5050563_-|acyl-CoA-dehydrogenase
MNFRFNEEQQMMRKMVRDFAQKEIAPFVPSMEQGVFPKEILQKMGELGLMGIPAPAKYGGAEMDFISYILAIEEISKVSATVGVILAVHTSVGMNPILYFGTEEQKEKYVSKLATGEYLGAFALTEPNAGSDAGSLKSRAVKKGDHYIINGSKVFITNGGEASTYIVFASTNPEAGKSGISAFIVEKDTPGLIIGKDEHKMGLLGSRTVQLTFEDMKVPAENLLGEEGQGFKVAMANLDVGRIGIGAQALGIAEAALACAIDYAKEREQFGKPIAAQQGIGFKLADMATSVEAARLLVYRAASLRAQGLPCGKEASIAKLFASKTAVEVAIEAVQVFGGYGYTKDYPVERFFRDAKITQIYEGTSEIQKLVISRAL
>NC_003909.8|WP_000116032.1|5050635_5051487_-|3-hydroxybutyryl-CoA-dehydrogenase
MSVQKIVVIGAGQMGSGIAQVCAMAGYDVKVQDLKQEQLDRGLAIITKNLARQVEKGRMKEEEKEATLNRLAVTLDLDCVKEADLIIEAAVEKMDIKKKIFANLDKIAPEHAILATNTSSLPITEIAAVTKRPEKVIGMHFMNPVPVMKLVEIIRGLATDDAVYETIEDITKKIGKVPVEVNDFPGFVSNRILLPMINEAIYTLYEGVATKEAIDEVMKLGMNHPMGPLTLADFIGLDTCLYIMEVLHEGLGDSKYRPCPLLRKYVNAGWLGRKTGRGFYVYE
>NC_003909.8|WP_000047988.1|5051536_5052718_-|acetyl-CoA-C-acetyltransferase
MSKTVILSAARTPVGKFGGSLKDVKATELGGIAIKAALERANVSASDVEEVIFGTVIQGGQGQIPSRQAARAAGIPWEVQTETVNKVCASGLRAVTLADQIIRTGDQSLIVAGGMESMSNSPYILRGARWGYRMGNNEVVDLNIADGLTCAFSGIHMGVYGGEVAKEDGISREAQDEWAYRSHQRAVSAHNEGRFEEEIVPVTIPQRKGDPIVVAKDEAPRADTTIEKLAKLKPVFDKTATVTAGNAPGLNDGGAALVLMSEDRAKQEGRKPLATILAHTAIAVESKDFPRTPGYAINALLEKTGKTIEDIDLFEINEAFAAVAIASTEIAGIDPEKLNVNGGAVAMGHPIGASGARIIVTLIHALKQRGGGIGIASICSGGGQGDAVMIEVH
>NC_003909.8|WP_001086788.1|5052827_5054939_-|(Fe-S)-binding-protein
MNSLLIMNWLAAIAVIAYAGYLFVYLIRTRMAYIQLGKKIEFDRRFKERWDLLKVNVFGQKKLLKDKKSGIIHVMFFYGFILVQFGAIDFVWKGLAPGSHLPLGPLYPAFTFFQEIVTLVILIAVFWAFHRRYVEKLVRLKRNFKSGLVLIFIGGLMISVLLGNGMGIIWHGEELSWSEPIASAIAYVFSGINETAAISVFYFSWWVHLLILLTFLVYVPQSKHAHLIAGPANVFFGRLSNPGKLEKIDFEDETQETFGVGKIEDFRQNQLIDLYACVECGRCTNMCPATGTGKMLSPMDLILKLRDHLTDKGAAVTSKAPWVPVVAFNNTQGNQLAMMAAGKGQQESAATTLAYDPSLIGDVITEEEIWACTTCRNCEDQCPVMNEHVDKIIDLRRYLVLTEGKMDAEAQRAMTNIERQGNPWGLNRKERETWRQGDDEVTVPTVKEKSKAGEEFEYLFWVGSMGSYDNRSQKIAISFAKLMNEAGISFAILGNKEKNSGDTPRRLGNEFVFQEMATKNIEEFEKAGVKKIVTIDPHAYNTFKNEYPDFGLQAEVYHHTELLAQWVKEGRLKPVHAIEETVTYHDSCYLGRYNEVYEAPRDILKAIPGVNLVEMARNRETGMCCGAGGGLMWMEETTGSRINVARTEQALAVQPSIIGTGCPYCLTMISDGTKAKEVEEKVQTLDVTEILERSVIGQKKEAI
>NC_003909.8|WP_000465820.1|5055245_5056439_+|cardiolipin-synthase
MFFLSLLLIGSTLWIVIDLSYGRIVHLKRVRSRSFPLRQSDFHLYTYGKDLYDALFTDIKQAKHHVHVLFFIVKNDKISREFLKLLIDKAKEGIEVRLLLDRLGSHHLSNEAIRSLQKHGVSFSFCHKVKFPFPFFSANQRNHRKITVIDGKIGYIGGFNIGEEYLGHNQKLGLWRDYHLRLTGEGIQDLQKQFLHDWLDDTDQNLLEASLYFPKQQPGTILHRFIPTDGAYLQNTFLYLIESAEKELFIGTPYFIPGRKIMNALLEARKRGVQITILVPEKADHPLVREAKFPYCRKLIQAGCNIYAFQQGFFHAKVIIVDDYICDIGTANFDMRSLYINHEINCLLYDEHFIQTVKNKFHEDLENASLLSLKDVSPNSLINRGKEWIGTILAFFL
>NC_003909.8|WP_000605888.1|5056471_5057425_+|UV-DNA-damage-repair-endonuclease-UvsE
MIMRFGYVSHAMALWDCSPAKTMTFTSFQKLSKQEREDKLYDVTRQNLEHTIRILHYNIAHEIPLYRLSSSIVPLATHPEVEFDYIGLFTPLWRKIGALIKEHNLRVSFHPNQFTLFTSDKPHITTNAITDMTYHYKVLDAIGIADSSYINIHVGGAYGNKEKAVERFHENIKKLPAHIKRQMTLENDDKTYTTAETLSICQKEKIPFVFDYHHHMANLCEEPLEELLPAIFETWAHTNILPKVHISSPKSKKEFRAHAEYIDLEFIKPFLHVAKKVNHNFDIMIESKQKDLAMLQFIHELSAIRGIKRINSSTLQW
>NC_003909.8|WP_000609937.1|5057553_5060232_+|DUF4084-domain-containing-protein
MINQKKYVHFVMIYIIIFSLWIFLIPKNLNIKEIGILFLFCFAALFSCYCLYKAIKKMKRGDKLFWVLLLCTCLCGLTMEITLFLHSLSIYDQVIFSYTALPFFIVQYILLFSGFAIKFIKHYSIRGLAQFSFDSIFIIIMNIYFTLTFILDRSSFRMLTTDHWVLIGYFIAQSLVIYAVISLYRREQYSASRISLIIGFTIILVYGYIHLFQLNAGMKTSSEVSYLIHTASILLIGLSSILYILDKPMQHETKTKYYRFDYVRFILPYFSIIITFSFIIFQPWDDKFMLIGLVLSLILLFLRQLYMWKDNQALIDTYEQLTTQLEDKVEEGASALSKSEQRYKSLFEDHPDAVFSLNMYGIFQQSNTACESLFTAYYCEVESYSLLHFIDSKDHDLLKKALQLTKKGRPQTLEVRTKEKEGYYYYLHITLIPTFINKEVVGMFGIARDITTLYEKQKQVEHLAFHDALTGLPNRRKFEKDLKNILNTAQTSASDVAVMFLDLDRFKKINDRLGHDVGDLLLIEVAKRLRSCLRSKDVVARQGGDEFTILLPDMYSEKSAAFIAEQILNILNKPFFIQGEELSITPSIGIAMYPDYGTDVTALMKNADMAMYRAKANGKNRFVFFSKEISIAQNEIQFLEGELAKALQQNEFFLEYQPQVSTKTKQIIGFEALLRWKHPKLGIVSPAQFIPLAEETGFIIELGNWILRTACLEAKRWHNQGFSHLKVGVNLSVVQFNHANLIPTISKVLEETELKPEALDIEITESIAINQNQSVVAKLEQLQNLGIQISIDDFGTGYSSLAYLTKYPINTLKIAREFICGITTSPLEEAIISSIITLSKELNLEVIAEGVETEEQWKFLYEQNCDHIQGFFISKPVSSKDVWRLLHKKTTV
>NC_003909.8|WP_000734728.1|5060249_5060396_-|quorum-sensing-peptide-PapR
MKKLLIGSLLTLAMAWGISLGDTALEKNQVISHNDQEVQLASDVPFEY

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NC_003909_2	2.3\|5047018\|24\|NC_003909\|CRT	5047018-5047041	24	NC_018878	Bacillus thuringiensis Bt407 plasmid BTB_502p, complete sequence	270501-270524	2	0.917
NC_003909_2	2.3\|5047018\|24\|NC_003909\|CRT	5047018-5047041	24	NZ_CP014203	Clostridium baratii strain CDC51267 plasmid pNPD11_1, complete sequence	65429-65452	3	0.875

1. spacer 2.3|5047018|24|NC_003909|CRT matches to NC_018878 (Bacillus thuringiensis Bt407 plasmid BTB_502p, complete sequence) position: , mismatch: 2, identity: 0.917

tcaagaaccttgtccaaatcttct	CRISPR spacer
tcaagaaccttgttcaactcttct	Protospacer
*************.*** ******

2. spacer 2.3|5047018|24|NC_003909|CRT matches to NZ_CP014203 (Clostridium baratii strain CDC51267 plasmid pNPD11_1, complete sequence) position: , mismatch: 3, identity: 0.875

tcaagaaccttgtccaaatcttct	CRISPR spacer
tcaagaaccttgtcaatatcttca	Protospacer
************** * ******

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

138255 : 188228

Bacillus_phage(33.33%)

tRNA,transposase,bacteriocin,integrase

attL 150786:150802|attR 178768:178784

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_011039908.1\|138255_138999_+\|tRNA	tRNA pseudouridine(38-40) synthase TruA	NA	NA	NA	NA
WP_001260793.1\|139151_139589_+	50S ribosomal protein L13	NA	NA	NA	NA
WP_000079986.1\|139610_140003_+	30S ribosomal protein S9	NA	NA	NA	NA
WP_001101006.1\|140165_140594_+	YbaK family protein	NA	NA	NA	NA
WP_000822436.1\|140660_141374_+	N-acetylmuramoyl-L-alanine amidase CwlD	E5DV68	Deep-sea_thermophilic_phage	1.2e-16	33.5
WP_000256603.1\|141518_142586_+	Mrp/NBP35 family ATP-binding protein	NA	NA	NA	NA
WP_000827521.1\|142642_143260_-	spore germination protein GerD	NA	NA	NA	NA
WP_001088515.1\|143399_144011_+	KinB signaling pathway activation protein KbaA	NA	NA	NA	NA
WP_000464707.1\|144115_144880_-	polysaccharide deacetylase family sporulation protein PdaB	NA	NA	NA	NA
WP_000900296.1\|145050_145269_+	hypothetical protein	NA	NA	NA	NA
150786:150802	attL	NA	NA	NA	NA
WP_000869571.1\|151253_152399_+	glycerate kinase	W6LM47	Streptococcus_phage	4.2e-53	41.8
WP_000711567.1\|152608_153502_+	arginase	A0A1V0SJM8	Klosneuvirus	1.1e-21	30.0
WP_001115703.1\|153750_154572_+	TIGR00159 family protein	NA	NA	NA	NA
WP_000359581.1\|154564_156052_+	hypothetical protein	NA	NA	NA	NA
WP_000521482.1\|156044_157391_+	phosphoglucosamine mutase	NA	NA	NA	NA
WP_001208183.1\|157677_157863_+	hypothetical protein	NA	NA	NA	NA
WP_000334168.1\|157875_159678_+	glutamine--fructose-6-phosphate transaminase (isomerizing)	M1HQK2	Paramecium_bursaria_Chlorella_virus	5.4e-103	39.9
WP_000730236.1\|160104_162642_+	DUF2726 domain-containing protein	NA	NA	NA	NA
WP_001084943.1\|163031_165779_+	ATP-dependent DNA helicase	A0A127AW80	Bacillus_phage	8.6e-36	26.0
WP_000687419.1\|166016_166253_-	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_000956454.1\|167218_167413_+	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_000794172.1\|167415_167922_+	DUF3278 domain-containing protein	NA	NA	NA	NA
WP_001047701.1\|168142_168349_-\|bacteriocin	Blp family class II bacteriocin	NA	NA	NA	NA
WP_001047700.1\|168374_168581_-\|bacteriocin	Blp family class II bacteriocin	NA	NA	NA	NA
WP_000764228.1\|168606_168813_-\|bacteriocin	Blp family class II bacteriocin	NA	NA	NA	NA
WP_000473021.1\|169055_171275_+	peptidase domain-containing ABC transporter	W8CYL7	Bacillus_phage	2.7e-48	29.8
WP_000041333.1\|171267_172581_+	HlyD family efflux transporter periplasmic adaptor subunit	NA	NA	NA	NA
WP_000710529.1\|172622_173303_+	hypothetical protein	NA	NA	NA	NA
WP_000181339.1\|173323_173596_+	hypothetical protein	NA	NA	NA	NA
WP_000273928.1\|173773_174238_-	hypothetical protein	NA	NA	NA	NA
WP_000284451.1\|174480_174981_+	DUF4652 domain-containing protein	NA	NA	NA	NA
WP_001129156.1\|175226_176066_+\|transposase	heteromeric transposase endonuclease subunit TnsA	NA	NA	NA	NA
WP_000605639.1\|176043_178185_+\|integrase,transposase	DDE-type integrase/transposase/recombinase	NA	NA	NA	NA
WP_000081379.1\|178181_179834_+	AAA family ATPase	NA	NA	NA	NA
178768:178784	attR	NA	NA	NA	NA
WP_000955035.1\|179827_181678_+	TniQ family protein	NA	NA	NA	NA
WP_000881882.1\|181706_183539_+	TniQ family protein	NA	NA	NA	NA
WP_001103054.1\|183853_185173_+	hypothetical protein	NA	NA	NA	NA
WP_000479526.1\|185194_185842_+	hypothetical protein	NA	NA	NA	NA
WP_000924690.1\|185810_186935_+	hypothetical protein	NA	NA	NA	NA
WP_001129185.1\|187394_188228_+\|transposase	heteromeric transposase endonuclease subunit TnsA	NA	NA	NA	NA

DBSCAN-SWA_2

338035 : 346408

Synechococcus_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000625677.1\|338035_339343_+	adenylosuccinate lyase	A0A2H4UUU6	Bodo_saltans_virus	4.9e-21	25.5
WP_001170542.1\|339431_340151_+	phosphoribosylaminoimidazolesuccinocarboxamide synthase	G8EYA2	Synechococcus_phage	5.2e-49	44.3
WP_000278826.1\|340143_340398_+	phosphoribosylformylglycinamidine synthase subunit PurS	NA	NA	NA	NA
WP_000666779.1\|340394_341078_+	phosphoribosylformylglycinamidine synthase subunit PurQ	NA	NA	NA	NA
WP_000055587.1\|341061_343281_+	phosphoribosylformylglycinamidine synthase II	A6N228	Microbacterium_phage	2.2e-162	41.2
WP_000879037.1\|343265_344681_+	amidophosphoribosyltransferase	A0A0M3SGR2	Mollivirus	4.3e-55	35.4
WP_001262431.1\|344783_345824_+	phosphoribosylformylglycinamidine cyclo-ligase	A0A0E3F760	Synechococcus_phage	6.1e-67	45.6
WP_000088595.1\|345820_346408_+	phosphoribosylglycinamide formyltransferase	M4QRX9	Synechococcus_phage	2.3e-26	36.0

DBSCAN-SWA_3

367569 : 434007

Erysipelothrix_phage(74.42%)

tail,holin,capsid,tRNA,terminase,protease,portal,head

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000086999.1\|367569_367860_+\|tRNA	Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatC	NA	NA	NA	NA
WP_000051445.1\|367875_369333_+\|tRNA	Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatA	NA	NA	NA	NA
WP_001047674.1\|369347_370775_+\|tRNA	Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatB	NA	NA	NA	NA
WP_000977677.1\|371244_372150_+	diacylglycerol kinase	A0A1V0SBJ0	Catovirus	2.8e-28	30.1
WP_000416676.1\|372295_373039_+	HAD family hydrolase	NA	NA	NA	NA
WP_001093016.1\|373193_374558_+	4-aminobutyrate--2-oxoglutarate transaminase	NA	NA	NA	NA
WP_000225163.1\|374674_376042_+	sigma 54-interacting transcriptional regulator	NA	NA	NA	NA
WP_000358113.1\|376034_377486_+	NADP-dependent succinate-semialdehyde dehydrogenase	NA	NA	NA	NA
WP_000263253.1\|377533_377857_+	multidrug efflux SMR transporter	NA	NA	NA	NA
WP_000891129.1\|377989_378481_+	DUF4352 domain-containing protein	NA	NA	NA	NA
WP_000007361.1\|378526_379756_-	aminopeptidase	NA	NA	NA	NA
WP_001233718.1\|379872_380955_-	polysaccharide deacetylase family protein	NA	NA	NA	NA
WP_001200497.1\|381129_382326_-	NupC family nucleoside transporter	NA	NA	NA	NA
WP_000105047.1\|382751_384134_+	23S rRNA (uracil(1939)-C(5))-methyltransferase RlmD	A0A2K5B251	Erysipelothrix_phage	4.5e-118	46.7
WP_001114081.1\|384455_384809_+	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_000577432.1\|384813_385866_+	DNA cytosine methyltransferase	G3CB01	Aeropyrum_pernix_spindle-shaped_virus	7.9e-22	49.1
WP_000494898.1\|385908_386865_-	NgoFVII family restriction endonuclease	NA	NA	NA	NA
WP_001199693.1\|386879_388742_-	hypothetical protein	NA	NA	NA	NA
WP_000772283.1\|388753_389902_-	NgoFVII family restriction endonuclease	NA	NA	NA	NA
WP_000028496.1\|389906_390137_-	helix-turn-helix transcriptional regulator	A0A2K5B261	Erysipelothrix_phage	2.1e-20	75.0
WP_000918425.1\|390338_392207_+	helix-turn-helix transcriptional regulator	E4ZFJ9	Streptococcus_phage	3.1e-77	29.9
WP_011039945.1\|392547_393213_+	sigma-70 family RNA polymerase sigma factor	A0A2K5B267	Erysipelothrix_phage	4.5e-15	31.9
WP_000682242.1\|393259_393478_+	hypothetical protein	A0A2I4R673	Erysipelothrix_phage	2.2e-19	61.1
WP_000034851.1\|393452_393776_+	hypothetical protein	A0A2K5B2A7	Erysipelothrix_phage	3.7e-23	62.4
WP_001064737.1\|394908_395457_+	DUF2815 family protein	A0A2K5B2A9	Erysipelothrix_phage	3.2e-91	89.5
WP_001084821.1\|395529_397464_+	DNA polymerase	A0A2K5B2B0	Erysipelothrix_phage	7.1e-295	74.9
WP_001124455.1\|397748_398348_-	TetR/AcrR family transcriptional regulator	NA	NA	NA	NA
WP_000573257.1\|398451_399165_+	GAP family protein	NA	NA	NA	NA
WP_000658732.1\|399190_399409_+	hypothetical protein	NA	NA	NA	NA
WP_000344037.1\|399793_400546_+	phage antirepressor Ant	A0A2H4IZX7	uncultured_Caudovirales_phage	3.9e-63	50.2
WP_000512442.1\|400545_400980_+	hypothetical protein	A0A2K5B270	Erysipelothrix_phage	2.4e-57	70.8
WP_000686160.1\|400976_403343_+	hypothetical protein	A0A1W6JQ82	Corynebacterium_phage	4.5e-243	51.8
WP_000891144.1\|403561_403843_+	VRR-NUC domain-containing protein	A0A2K5B272	Erysipelothrix_phage	2.2e-27	70.0
WP_000876794.1\|403823_405185_+	DEAD/DEAH box helicase	A0A2K5B273	Erysipelothrix_phage	2.9e-186	78.6
WP_000338537.1\|405184_405403_+	hypothetical protein	A0A2K5B274	Erysipelothrix_phage	1.6e-14	57.1
WP_000987998.1\|405399_405813_+	DUF1492 domain-containing protein	A0A2K5B275	Erysipelothrix_phage	3.8e-12	31.6
WP_001124952.1\|405969_406329_+	HNH endonuclease	A0A2K5B276	Erysipelothrix_phage	2.0e-41	64.4
WP_001029957.1\|406440_406992_+\|terminase	terminase	A0A2K5B277	Erysipelothrix_phage	3.9e-81	78.7
WP_000044888.1\|407012_408188_+	methionine adenosyltransferase	A0A2K5B278	Erysipelothrix_phage	4.8e-177	76.8
WP_000904378.1\|408168_409410_+	DNA modification methylase	A0A2I4R670	Erysipelothrix_phage	1.8e-187	76.3
WP_000041102.1\|409402_411562_+	DNA cytosine methyltransferase	A0A2K9V3X0	Faecalibacterium_phage	2.4e-33	60.6
WP_001166740.1\|411662_412355_+	hypothetical protein	A0A2K5B280	Erysipelothrix_phage	4.1e-51	49.3
WP_001021293.1\|412351_412579_+	DUF4314 domain-containing protein	NA	NA	NA	NA
WP_001002418.1\|412657_412846_+	DUF5049 domain-containing protein	NA	NA	NA	NA
WP_001228683.1\|412934_414539_+\|terminase	terminase large subunit	A0A2K5B285	Erysipelothrix_phage	2.3e-267	83.5
WP_001048933.1\|414583_415828_+\|portal	phage portal protein	A0A2K5B287	Erysipelothrix_phage	2.4e-179	72.4
WP_001225249.1\|415828_416518_+\|protease	Clp protease ClpP	Q6DMU1	Streptococcus_phage	1.3e-73	63.6
WP_000034931.1\|416537_417731_+\|capsid	phage major capsid protein	A0A2I4R671	Erysipelothrix_phage	1.2e-183	80.6
WP_000121277.1\|417743_417956_+	hypothetical protein	A0A2K5B289	Erysipelothrix_phage	2.8e-19	70.3
WP_000257312.1\|417982_418303_+\|head,tail	phage gp6-like head-tail connector protein	A0A2K5B290	Erysipelothrix_phage	6.3e-39	81.0
WP_000007827.1\|418304_418640_+\|head	phage head closure protein	A0A2K5B291	Erysipelothrix_phage	3.4e-27	54.5
WP_001140706.1\|418645_419077_+	HK97 gp10 family phage protein	A0A2K5B292	Erysipelothrix_phage	2.3e-44	60.1
WP_001022899.1\|419073_419415_+	hypothetical protein	A0A2K5B293	Erysipelothrix_phage	2.2e-29	52.3
WP_000190903.1\|419418_420009_+\|tail	phage tail protein	A0A2K5B294	Erysipelothrix_phage	1.4e-73	69.9
WP_000368171.1\|420020_420407_+	hypothetical protein	A0A2K5B295	Erysipelothrix_phage	4.3e-42	72.6
WP_000774661.1\|420609_423030_+	hypothetical protein	A0A2K5B297	Erysipelothrix_phage	3.0e-24	47.2
WP_000424206.1\|423043_423895_+\|tail	phage tail family protein	E2ELJ6	Clostridium_phage	3.0e-40	34.7
WP_000424787.1\|423897_425835_+	siphovirus ReqiPepy6 Gp37-like family protein	D2J072	Enterococcus_phage	3.6e-28	31.1
WP_000415659.1\|425852_426356_+	hypothetical protein	A0A1C9LWP9	Streptomyces_phage	1.1e-08	36.2
WP_041184639.1\|426372_428727_+	hypothetical protein	NA	NA	NA	NA
WP_000659472.1\|428803_429244_+\|holin	phage holin family protein	A0A2K5B2A2	Erysipelothrix_phage	1.6e-45	64.5
WP_000776688.1\|429275_429977_+	N-acetylmuramoyl-L-alanine amidase	H7BVK7	unidentified_phage	1.5e-48	43.5
WP_049779039.1\|430188_430395_+	hypothetical protein	A0A2K5B2B1	Erysipelothrix_phage	2.0e-06	50.0
WP_000724418.1\|430456_432019_+	recombinase family protein	A0A2K5B2B2	Erysipelothrix_phage	8.6e-158	54.2
WP_028988101.1\|432018_432432_+	recombinase	NA	NA	NA	NA
WP_000301253.1\|432435_434007_+	recombinase family protein	A0A2K5B2B4	Erysipelothrix_phage	1.4e-176	60.9

DBSCAN-SWA_4

1968961 : 1978291

Bacillus_phage(71.43%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000755518.1\|1968961_1970242_+	C40 family peptidase	A0A1V0DZX6	Clostridioides_phage	4.5e-11	31.5
WP_001194313.1\|1970339_1971104_-	alpha/beta hydrolase	NA	NA	NA	NA
WP_000453871.1\|1971343_1973104_+	ABC transporter ATP-binding protein	W8CYL7	Bacillus_phage	1.4e-268	96.5
WP_000937028.1\|1973192_1973870_+	response regulator transcription factor	W8CYM9	Bacillus_phage	1.7e-118	93.8
WP_001254314.1\|1973866_1974940_+	sensor histidine kinase	W8CYF6	Bacillus_phage	1.4e-175	89.9
WP_001131475.1\|1974963_1975527_-	DUF3139 domain-containing protein	NA	NA	NA	NA
WP_000818985.1\|1975745_1976465_+	3-ketoacyl-ACP reductase	W8CYX9	Bacillus_phage	5.9e-61	100.0
WP_000061725.1\|1976613_1977285_+	O-methyltransferase	W8CYT3	Bacillus_phage	7.7e-63	89.1
WP_001258521.1\|1977418_1978291_+	aminoglycoside 6-adenylyltransferase	A0A1X9I6F2	Streptococcus_phage	1.1e-64	44.0

DBSCAN-SWA_5

4172545 : 4235644

Klosneuvirus(22.22%)

coat,tRNA,protease

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000125362.1\|4172545_4173685_-\|tRNA	tRNA guanosine(34) transglycosylase Tgt	A0A1B1IVQ4	uncultured_Mediterranean_phage	2.5e-82	42.1
WP_000354028.1\|4173697_4174750_-\|tRNA	tRNA preQ1(34) S-adenosylmethionine ribosyltransferase-isomerase QueA	NA	NA	NA	NA
WP_000138163.1\|4174769_4174970_-	DUF2905 domain-containing protein	NA	NA	NA	NA
WP_000344461.1\|4174966_4175968_-	Holliday junction branch migration DNA helicase RuvB	A0A127AWE7	Bacillus_phage	4.0e-07	26.3
WP_000464508.1\|4175973_4176591_-	Holliday junction DNA helicase RuvA	NA	NA	NA	NA
WP_000871209.1\|4176791_4177322_-	BofC C-terminal domain-containing protein	NA	NA	NA	NA
WP_000723578.1\|4177442_4178372_-	DMT family transporter	NA	NA	NA	NA
WP_000426920.1\|4178439_4178760_-	winged helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_000721236.1\|4179204_4179639_+	hypothetical protein	NA	NA	NA	NA
WP_001093542.1\|4179671_4180313_-	YhcN/YlaJ family sporulation lipoprotein	NA	NA	NA	NA
WP_000690773.1\|4180496_4182338_-\|coat	spore coat assembly protein ExsA	NA	NA	NA	NA
WP_000025300.1\|4182563_4183670_-	quinolinate synthase NadA	NA	NA	NA	NA
WP_001092214.1\|4183700_4184534_-	carboxylating nicotinate-nucleotide diphosphorylase	NA	NA	NA	NA
WP_001138548.1\|4184553_4186083_-	L-aspartate oxidase	NA	NA	NA	NA
WP_000973743.1\|4186235_4187378_+	IscS subfamily cysteine desulfurase	A0A1X7QGF3	Faustovirus	5.4e-32	29.8
WP_000812272.1\|4187377_4187920_+	transcription repressor NadR	NA	NA	NA	NA
WP_000753185.1\|4188238_4189471_-	NADH:flavin oxidoreductase/NADH oxidase family protein	NA	NA	NA	NA
WP_000799860.1\|4189631_4189994_-	winged helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_085965931.1\|4190238_4191678_-	NADP-dependent glyceraldehyde-3-phosphate dehydrogenase	NA	NA	NA	NA
WP_000039471.1\|4192207_4192519_+	winged helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_000222508.1\|4192713_4193655_+	alpha/beta fold hydrolase	NA	NA	NA	NA
WP_000510688.1\|4193958_4194606_+	MOSC domain-containing protein	NA	NA	NA	NA
WP_000621719.1\|4194669_4195521_-	prephenate dehydratase	NA	NA	NA	NA
WP_001026315.1\|4195617_4197531_-	ABC transporter permease	NA	NA	NA	NA
WP_001011384.1\|4197580_4199503_-	ABC transporter permease	NA	NA	NA	NA
WP_000114533.1\|4199477_4200254_-	ABC transporter ATP-binding protein	W5SAS9	Pithovirus	2.1e-19	31.0
WP_000864964.1\|4200347_4201430_-	HAMP domain-containing histidine kinase	NA	NA	NA	NA
WP_000276716.1\|4201419_4202127_-	response regulator transcription factor	NA	NA	NA	NA
WP_000497114.1\|4202369_4203656_-	GTPase ObgE	NA	NA	NA	NA
WP_001037006.1\|4203655_4204204_-	Spo0B domain-containing protein	NA	NA	NA	NA
WP_000944958.1\|4204267_4204558_-	50S ribosomal protein L27	NA	NA	NA	NA
WP_011040706.1\|4204561_4204906_-\|protease	ribosomal-processing cysteine protease Prp	NA	NA	NA	NA
WP_000270908.1\|4204917_4205226_-	50S ribosomal protein L21	NA	NA	NA	NA
WP_000855436.1\|4205395_4206784_-	Rne/Rng family ribonuclease	NA	NA	NA	NA
WP_000599048.1\|4206851_4207712_-\|protease	stage IV sporulation intramembrane metalloprotease SpoIVFB	NA	NA	NA	NA
WP_000797467.1\|4207704_4208451_-	stage IV sporulation protein SpoIVFA	NA	NA	NA	NA
WP_000503311.1\|4208584_4209382_-	septum site-determining protein MinD	NA	NA	NA	NA
WP_000391517.1\|4209384_4210071_-	septum site-determining protein MinC	NA	NA	NA	NA
WP_000975746.1\|4210106_4210652_-	rod shape-determining protein MreD	NA	NA	NA	NA
WP_001135480.1\|4210666_4211518_-	rod shape-determining protein MreC	NA	NA	NA	NA
WP_000466737.1\|4211559_4212579_-	rod shape-determining protein MreB	NA	NA	NA	NA
WP_001013385.1\|4212736_4213414_-	DNA repair protein RadC	NA	NA	NA	NA
WP_000720486.1\|4213460_4214036_-	septum formation inhibitor Maf	NA	NA	NA	NA
WP_000360986.1\|4214257_4215220_-	hypothetical protein	NA	NA	NA	NA
WP_000582082.1\|4215385_4216687_-	bifunctional tetrahydrofolate synthase/dihydrofolate synthase	NA	NA	NA	NA
WP_000072229.1\|4216780_4219426_-\|tRNA	valine--tRNA ligase	A0A1V0SK04	Klosneuvirus	4.7e-164	42.7
WP_000366999.1\|4219819_4220845_-\|coat	spore coat protein YsxE	NA	NA	NA	NA
WP_000179722.1\|4220907_4221885_-	stage VI sporulation protein D	NA	NA	NA	NA
WP_000712955.1\|4221994_4223284_-	glutamate-1-semialdehyde 2,1-aminomutase	A0A1V0SKB7	Klosneuvirus	1.7e-05	34.1
WP_001087060.1\|4223283_4224273_-	porphobilinogen synthase	NA	NA	NA	NA
WP_000992369.1\|4224293_4225046_-	uroporphyrinogen-III synthase	NA	NA	NA	NA
WP_001226411.1\|4225048_4225978_-	hydroxymethylbilane synthase	NA	NA	NA	NA
WP_000008996.1\|4225993_4226827_-	cytochrome c biogenesis protein CcsA	NA	NA	NA	NA
WP_000547872.1\|4226844_4228179_-\|tRNA	glutamyl-tRNA reductase	NA	NA	NA	NA
WP_000228199.1\|4228595_4229048_+	MarR family transcriptional regulator	NA	NA	NA	NA
WP_000359781.1\|4229050_4229467_+	organic hydroperoxide resistance protein	NA	NA	NA	NA
WP_000869113.1\|4229501_4230098_-	ribosome biogenesis GTP-binding protein YsxC	NA	NA	NA	NA
WP_000097298.1\|4230094_4232425_-	endopeptidase La	A0A0R6PGP8	Moraxella_phage	8.6e-178	43.7
WP_041184788.1\|4232607_4234278_-\|protease	ATP-dependent protease LonB	E3T4F6	Cafeteria_roenbergensis_virus	7.4e-14	33.0
WP_000472282.1\|4234384_4235644_-\|protease	ATP-dependent Clp protease ATP-binding subunit ClpX	G3M9Z9	Bacillus_virus	1.3e-148	66.1

DBSCAN-SWA_6

4314900 : 4322585

Staphylococcus_phage(16.67%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000221082.1\|4314900_4315824_-	ABC transporter ATP-binding protein	A0A2H4PQG7	Staphylococcus_phage	2.0e-45	45.1
WP_011040738.1\|4315949_4316885_-	HAMP domain-containing histidine kinase	W8CYF6	Bacillus_phage	1.2e-21	25.9
WP_000018055.1\|4316886_4317579_-	response regulator transcription factor	B5LWA6	Feldmannia_species_virus	1.4e-06	28.8
WP_001293581.1\|4317748_4317922_+	hypothetical protein	NA	NA	NA	NA
WP_001014318.1\|4317922_4318117_+	YwbE family protein	NA	NA	NA	NA
WP_001255962.1\|4318156_4319356_-	class I SAM-dependent rRNA methyltransferase	W6LLI2	Streptococcus_phage	2.8e-71	41.2
WP_000587815.1\|4319654_4319978_+	heme oxygenase	NA	NA	NA	NA
WP_001086114.1\|4320044_4320809_-	class B sortase	NA	NA	NA	NA
WP_000403753.1\|4320841_4321612_-	ABC transporter ATP-binding protein	G3M9Y6	Bacillus_virus	2.2e-13	26.1
WP_001036854.1\|4321601_4322585_-	iron ABC transporter permease	A0A2H4IY97	uncultured_Caudovirales_phage	6.5e-18	27.7

DBSCAN-SWA_7

4697371 : 4740384

Prochlorococcus_phage(16.67%)

protease,coat

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000447121.1\|4697371_4698049_-\|protease	CPBP family intramembrane metalloprotease	NA	NA	NA	NA
WP_041184796.1\|4698123_4698927_-	DUF4111 domain-containing protein	NA	NA	NA	NA
WP_000248590.1\|4698979_4699288_-	YuzD family protein	NA	NA	NA	NA
WP_000431159.1\|4699494_4699731_+	NifU family protein	Q58MC7	Prochlorococcus_phage	2.0e-10	46.6
WP_001125488.1\|4699926_4700142_+	hypothetical protein	NA	NA	NA	NA
WP_000581277.1\|4700203_4701205_-\|coat	spore coat protein CotS	NA	NA	NA	NA
WP_000665103.1\|4701325_4701817_+	phosphatidylglycerophosphatase A	G3MBC5	Bacillus_virus	3.5e-41	53.8
WP_000402410.1\|4701837_4702317_-	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_001106074.1\|4702478_4703582_+	HpcH/HpaI aldolase/citrate lyase family protein	NA	NA	NA	NA
WP_000856289.1\|4703526_4704873_+	phosphoribosyltransferase domain-containing protein	NA	NA	NA	NA
WP_000241499.1\|4704878_4705991_+\|protease	cysteine protease StiP family protein	A0A172Q0S8	Acinetobacter_phage	8.9e-40	32.0
WP_000575371.1\|4705987_4706803_+	HAD hydrolase family protein	NA	NA	NA	NA
WP_000683407.1\|4707347_4707929_+	NAD(P)H-dependent oxidoreductase	NA	NA	NA	NA
WP_000276467.1\|4708154_4708919_-	TIGR01457 family HAD-type hydrolase	NA	NA	NA	NA
WP_000503352.1\|4709028_4709661_-	transcriptional regulator	NA	NA	NA	NA
WP_000274011.1\|4709732_4710173_-	DUF86 domain-containing protein	NA	NA	NA	NA
WP_000439091.1\|4710320_4711292_+	class II fructose-bisphosphatase	NA	NA	NA	NA
WP_000392606.1\|4711309_4711576_+	DUF3055 domain-containing protein	NA	NA	NA	NA
WP_001174570.1\|4711947_4712445_+	hypothetical protein	NA	NA	NA	NA
WP_000435941.1\|4712481_4712784_-	DUF1027 domain-containing protein	NA	NA	NA	NA
WP_000744038.1\|4712902_4713481_+	YhcN/YlaJ family sporulation lipoprotein	NA	NA	NA	NA
WP_000178117.1\|4713519_4714251_-	MerR family transcriptional regulator	NA	NA	NA	NA
WP_011040809.1\|4714351_4715167_+\|protease	YhfC family intramembrane metalloprotease	NA	NA	NA	NA
WP_000738183.1\|4715190_4715634_-	hypothetical protein	NA	NA	NA	NA
WP_000721033.1\|4715766_4716321_+	histidine phosphatase family protein	NA	NA	NA	NA
WP_000272744.1\|4716395_4716875_+	YbaK/EbsC family protein	NA	NA	NA	NA
WP_000166370.1\|4716895_4717792_-	lipoyl synthase	NA	NA	NA	NA
WP_000944661.1\|4717981_4718965_+	M23 family metallopeptidase	NA	NA	NA	NA
WP_011040810.1\|4719001_4719733_-	sporulation protein YunB	NA	NA	NA	NA
WP_000248463.1\|4719787_4720090_-	DUF1805 domain-containing protein	NA	NA	NA	NA
WP_071713399.1\|4720155_4721547_-	bifunctional metallophosphatase/5'-nucleotidase	NA	NA	NA	NA
WP_000356633.1\|4722145_4722475_+	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_000151201.1\|4722474_4723221_+	VanZ family protein	NA	NA	NA	NA
WP_001118823.1\|4723462_4724860_-	Fe-S cluster assembly protein SufB	NA	NA	NA	NA
WP_000009523.1\|4724908_4725340_-	iron-sulfur cluster assembly scaffold protein SufU	A0A0K1LS29	Mycobacterium_phage	1.5e-14	37.6
WP_001020761.1\|4725329_4726550_-	cysteine desulfurase SufS	Q2XUY6	environmental_halophage	3.6e-119	48.1
WP_000152160.1\|4726549_4727842_-	Fe-S cluster assembly protein SufD	NA	NA	NA	NA
WP_000929157.1\|4727857_4728643_-	Fe-S cluster assembly ATPase SufC	NA	NA	NA	NA
WP_000722393.1\|4728881_4729688_-	methionine ABC transporter substrate-binding lipoprotein MetQ	NA	NA	NA	NA
WP_000735105.1\|4729760_4730573_-	methionine ABC transporter substrate-binding lipoprotein MetQ	NA	NA	NA	NA
WP_000359556.1\|4730596_4731262_-	ABC transporter permease	NA	NA	NA	NA
WP_000601777.1\|4731254_4732280_-	methionine ABC transporter ATP-binding protein	NA	NA	NA	NA
WP_000781222.1\|4732693_4733038_-	hypothetical protein	NA	NA	NA	NA
WP_001974355.1\|4733192_4733501_-	thioredoxin family protein	NA	NA	NA	NA
WP_000263237.1\|4733504_4733849_-	hypothetical protein	NA	NA	NA	NA
WP_000026900.1\|4734175_4734559_-	glycine cleavage system protein GcvH	NA	NA	NA	NA
WP_000218967.1\|4734600_4734966_-	arsenate reductase family protein	M1PLC0	Streptococcus_phage	6.7e-21	48.6
WP_000826900.1\|4735470_4735998_-	hypothetical protein	NA	NA	NA	NA
WP_000713765.1\|4736141_4736789_+	phosphatase PAP2 family protein	NA	NA	NA	NA
WP_000666177.1\|4736845_4737859_-	PTS sugar transporter subunit IIC	NA	NA	NA	NA
WP_001002987.1\|4739076_4739325_-\|coat	spore coat protein	NA	NA	NA	NA
WP_001180555.1\|4739338_4739524_-	hypothetical protein	NA	NA	NA	NA
WP_000048022.1\|4739670_4740384_-\|protease	CPBP family intramembrane metalloprotease	NA	NA	NA	NA

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. NC_003909

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection