CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NC_006833	Wolbachia endosymbiont strain TRS of Brugia malayi, complete sequence	1 crisprs	cas3	0	1	2	0

Results visualization

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CRISPR-Cas detection and classification

Crispr_ID: NC_006833_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_006833_1

99455-99537

Orphan

Consensus_repeat	Method
CCAAATTTAAAGTGTGTTAATTTACAAAA	CRISPRCasFinder

1 spacers

The CRISPR arrays of NC_006833_1

>merge|NC_006833|1|99455-99537|CRISPRCasFinder
CCAAATTTAAAGTGTGTTAATTTACAAAAGGAACCACCACCGGTGCCGCCTAAGCCAAATTTAAAGTGTGTTAATTTACAAAA

>NC_006833|1|1|99455-99537|CRISPRCasFinder
CCAAATTTAAAGTGTGTTAATTTACAAAA	GGAACCACCACCGGTGCCGCCTAAG
CCAAATTTAAAGTGTGTTAATTTACAAAA

Protein	Signature genes	Signature genes Name	Protein_function
NC_006833.1\|WP_011256280.1\|100940_101318_+\|holo-[acyl-carrier-protein]-synthase	unknown	unknown	gnl\|CDD\|237780
NC_006833.1\|WP_011256281.1\|101340_102132_-\|prolipoprotein-diacylglyceryl-transferase	unknown	unknown	gnl\|CDD\|234599
NC_006833.1\|WP_011256268.1\|89016_89241_-\|hypothetical-protein	unknown	unknown	unknown
NC_006833.1\|WP_011256279.1\|99666_100944_+\|proline--tRNA-ligase	unknown	unknown	gnl\|CDD\|237059
NC_006833.1\|WP_011256276.1\|95918_96713_+\|polysaccharide-deacetylase-family-protein	unknown	unknown	gnl\|CDD\|213022
NC_006833.1\|WP_011256284.1\|104273_104864_-\|CvpA-family-protein	unknown	unknown	gnl\|CDD\|367140
NC_006833.1\|WP_011256285.1\|104920_105517_-\|riboflavin-synthase	unknown	unknown	gnl\|CDD\|236455
NC_006833.1\|WP_011256289.1\|107353_108397_+\|phenylalanine--tRNA-ligase-subunit-alpha	unknown	unknown	gnl\|CDD\|234780
NC_006833.1\|WP_158676317.1\|103880_104030_+\|hypothetical-protein	unknown	unknown	unknown
NC_006833.1\|WP_011256273.1\|94155_94413_+\|DUF2312-domain-containing-protein	unknown	unknown	gnl\|CDD\|237474
NC_006833.1\|WP_011256274.1\|94413_94977_+\|UbiX-family-flavin-prenyltransferase	unknown	unknown	gnl\|CDD\|223241
NC_006833.1\|WP_011256277.1\|96703_98269_+\|penicillin-binding-protein	unknown	unknown	gnl\|CDD\|274573
NC_006833.1\|WP_011256269.1\|89237_89459_-\|hypothetical-protein	unknown	unknown	unknown
NC_006833.1\|WP_011256282.1\|102138_102588_-\|SsrA-binding-protein-SmpB	unknown	unknown	gnl\|CDD\|235455
NC_006833.1\|WP_011256275.1\|94980_95868_+\|bifunctional-methylenetetrahydrofolate-dehydrogenase/methenyltetrahydrofolate-cyclohydrolase-FolD	unknown	unknown	gnl\|CDD\|172675
NC_006833.1\|WP_136132027.1\|90083_90362_-\|hypothetical-protein	unknown	unknown	unknown
NC_006833.1\|WP_011256283.1\|103117_103330_+\|hypothetical-protein	unknown	unknown	unknown
NC_006833.1\|WP_011256271.1\|90507_90753_-\|hypothetical-protein	unknown	unknown	unknown
NC_006833.1\|WP_011256288.1\|106981_107209_-\|hypothetical-protein	unknown	unknown	unknown
NC_006833.1\|WP_011256272.1\|92859_94146_+\|DUF21-domain-containing-protein	unknown	unknown	gnl\|CDD\|226911

Protein	Function_ID	Function_description	E-value
NC_006833.1\|WP_011256282.1\|102138_102588_-\|SsrA-binding-protein-SmpB	gnl\|CDD\|235455	PRK05422, smpB, SsrA-binding protein SmpB.	1.39966e-77
NC_006833.1\|WP_011256280.1\|100940_101318_+\|holo-[acyl-carrier-protein]-synthase	gnl\|CDD\|237780	PRK14659, acpS, holo-[acyl-carrier-protein] synthase.	1.10874e-71
NC_006833.1\|WP_011256279.1\|99666_100944_+\|proline--tRNA-ligase	gnl\|CDD\|237059	PRK12325, PRK12325, prolyl-tRNA synthetase; Provisional.	0
NC_006833.1\|WP_011256276.1\|95918_96713_+\|polysaccharide-deacetylase-family-protein	gnl\|CDD\|213022	cd10917, CE4_NodB_like_6s_7s, Catalytic NodB homology domain of rhizobial NodB-like proteins. This family belongs to the large and functionally diverse carbohydrate esterase 4 (CE4) superfamily, whose members show strong sequence similarity with some variability due to their distinct carbohydrate substrates. It includes many rhizobial NodB chitooligosaccharide N-deacetylase (EC 3.5.1.-)-like proteins, mainly from bacteria and eukaryotes, such as chitin deacetylases (EC 3.5.1.41), bacterial peptidoglycan N-acetylglucosamine deacetylases (EC 3.5.1.-), and acetylxylan esterases (EC 3.1.1.72), which catalyze the N- or O-deacetylation of substrates such as acetylated chitin, peptidoglycan, and acetylated xylan. All members of this family contain a catalytic NodB homology domain with the same overall topology and a deformed (beta/alpha)8 barrel fold with 6- or 7 strands. Their catalytic activity is dependent on the presence of a divalent cation, preferably cobalt or zinc, and they employ a conserved His-His-Asp zinc-binding triad closely associated with the conserved catalytic base (aspartic acid) and acid (histidine) to carry out acid/base catalysis. Several family members show diversity both in metal ion specificities and in the residues that coordinate the metal.	6.43347e-75
NC_006833.1\|WP_011256285.1\|104920_105517_-\|riboflavin-synthase	gnl\|CDD\|236455	PRK09289, PRK09289, riboflavin synthase.	6.7638e-94
NC_006833.1\|WP_011256281.1\|101340_102132_-\|prolipoprotein-diacylglyceryl-transferase	gnl\|CDD\|234599	PRK00052, PRK00052, prolipoprotein diacylglyceryl transferase; Reviewed.	8.21289e-104
NC_006833.1\|WP_011256289.1\|107353_108397_+\|phenylalanine--tRNA-ligase-subunit-alpha	gnl\|CDD\|234780	PRK00488, pheS, phenylalanyl-tRNA synthetase subunit alpha; Validated.	0
NC_006833.1\|WP_011256273.1\|94155_94413_+\|DUF2312-domain-containing-protein	gnl\|CDD\|237474	PRK13694, PRK13694, hypothetical protein; Provisional.	2.70495e-30
NC_006833.1\|WP_011256274.1\|94413_94977_+\|UbiX-family-flavin-prenyltransferase	gnl\|CDD\|223241	COG0163, UbiX family flavin prenyltransferase [Coenzyme transport and metabolism].	2.76317e-102
NC_006833.1\|WP_011256277.1\|96703_98269_+\|penicillin-binding-protein	gnl\|CDD\|274573	TIGR03423, pbp2_mrdA, penicillin-binding protein 2. Members of this protein family are penicillin-binding protein 2 (PBP-2), a protein whose gene (designated pbpA or mrdA) generally is found next to the gene for RodA, a protein required for rod (bacillus) shape in many bacteria. PBP-2 acts as a transpeptidase for cell elongation (hence, rod-shape). [Cell envelope, Biosynthesis and degradation of murein sacculus and peptidoglycan].	4.44511e-169
NC_006833.1\|WP_011256275.1\|94980_95868_+\|bifunctional-methylenetetrahydrofolate-dehydrogenase/methenyltetrahydrofolate-cyclohydrolase-FolD	gnl\|CDD\|172675	PRK14187, PRK14187, bifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase FolD.	0
NC_006833.1\|WP_011256284.1\|104273_104864_-\|CvpA-family-protein	gnl\|CDD\|367140	pfam02674, Colicin_V, Colicin V production protein. Colicin V production protein is required in E. Coli for colicin V production from plasmid pColV-K30. This protein is coded for in the purF operon.	1.99176e-20
NC_006833.1\|WP_011256272.1\|92859_94146_+\|DUF21-domain-containing-protein	gnl\|CDD\|226911	COG4536, CorB, Putative Mg2+ and Co2+ transporter CorB [Inorganic ion transport and metabolism].	2.04777e-143

>NC_006833.1|WP_011256277.1|96703_98269_+|penicillin-binding-protein
MWIKNKVFNRRAFILGGIQLTISTIFSCRLYSLQIRNRQKYEKLADNNRIRVAAIMPKRGRILDRNGIELAVDKISYIVLFDKQKISSEEVDWETLSEIESNVTKSSETKITALYKRHYPFGSICSHTLGYTKKQQGINEAGISGIEYTYDHILKGKPGRSEQEINSKKRIVRELSSIPQQDGQDVQLTIDIDLQEKIAEIFKGHKGSVTAIDVGNGEILTLYNSPSYDNNLFANKLSNEAWEGLNTPSLPLVNRALSYQIPPGSIFKIIVALAGLKDGIITPEEKFSCVGYMKIGERRFCCLKSKVHGYVSLNEAMALSCNTYFYNIGKKISVDSLVEMARKFGIGSGPLIGAFKEEAPGLLPDKDWRTRKLYSEWYLGDTVNLVIGQGYVLTTPLQLAVLAARIATGKEVIPRIEMSKTMQDFPDIDIAHEHLSIVRKAMFNMVNIKAGTYRKGLSSIRIAGKTGTPEINSKGESHKLFIAYGPYHDPRYAISVFIEYGKAPRQDVAMANEILRYMLKG
>NC_006833.1|WP_011256276.1|95918_96713_+|polysaccharide-deacetylase-family-protein
MGLKAWLITTFLLLYPSATFCDDCNFNLPYRGLSCNLDLSHKNLSNIKKLLNNSDKFVALTFDDGPSSNRVNNIINILENYKAKATFFLLGERINKKTSEIVKKIYNAGHELGNHSWSHKKLTSLSSEKQLQELEKTNMVIKNAIERDVKWFRSPYGCHDDNLIKNTNQLNMCSILWTVDSLDWQGDKPEILVDRVVGNVHNGAIILFHDHDNKSNTVEALPQIIKILKKLGYEFVTLSEWEERVCKAKGVSMGEGVFKKILCG
>NC_006833.1|WP_011256275.1|94980_95868_+|bifunctional-methylenetetrahydrofolate-dehydrogenase/methenyltetrahydrofolate-cyclohydrolase-FolD
MTIIIDGKKIASGLCEKLSQRIDVLKREHSIFPCLKVIFVGNNPASQVYVRNKQKKAESIGISSETIVLPDNILENELIEKINELNNDRFVNGILVQLPLPNHINASKVINTVSVEKDVDAFHRENVGKLVKGEKNCLVPCTPKGALHLIKLVETNLSGKNAVVIGRSNIVGKPMFHLLLQENCTVTILHSQSKDLAEYCSKADVVVTAVGKPNFVQEGWIKEGAIVIDVGINSVSIEGKTKLIGDVDFDRVKEKTKAITPVPGGVGPMTIAFLMINTVIAACLQKKVDASDFVS
>NC_006833.1|WP_011256274.1|94413_94977_+|UbiX-family-flavin-prenyltransferase
MNNRIVIGISGASGSIYGMHILKALKGADCETHLVISRAGKTTIAHEITERLEDITSLADFYYSEEKIGEKIASGSFKTSGMIVAPCSMKTMSEIASGVTSNLLTRAADVTLKERRKLVLIVRESPLHLGHLQNMLKLTEMGAIIAPPMPAFYTKPKSLEDIISHSISKVLSLFDIKLPDFKEWQGV
>NC_006833.1|WP_011256273.1|94155_94413_+|DUF2312-domain-containing-protein
MGDAVKVIAEELKGYIERIEKLEQEKKNVQDQIHDVYAKAADKGWNIKVMKQIIRLRKMEDGDRAEQEILLNTYKRALGMSCEEN
>NC_006833.1|WP_011256272.1|92859_94146_+|DUF21-domain-containing-protein
MDWLLVSILSIIFVLLILSFLFSGAEIGLTSVSRSRVNKLKLDGNKRAKIIDHLLNKKELTIGTILLGNTIINITCSVLFTAIFINLFGNESVFLSTIVMTFCILLFCEVLPKTYAMQNPEKFTSFSAYFVLFFVKIFSPLTLGIQFIVNFILKLCGFHKNREAISAADAMRNMIALHRSEGTMLQQDLDMLSSILDLAETEISEIMTHRRNLFSLDIDRNKEELIKEILTSSHSRVPLWQKELDNIVGVVHVKNLINALREKDNKIEEVDIAQVMSKPCFLPESTPLSVQLHNFRKNRKHLAFVIDEYGALQGIVTLEDILEEIVGEISDEHDLITENFIKKMSDNVYHIEGKSTIRDINRQLHWDLPDEEATTLAGMIVNEIERIPDEGEEFSMFGFYFRILKKDKNIITVIEVQVKTDNTVTAID
>NC_006833.1|WP_011256271.1|90507_90753_-|hypothetical-protein
MEEKDSNFAMEKPGNNYVGCISSENGECKNFYDLKLNFVKYNSGNNSSLYPYYYNLENFGNFLEVDVKLRELIGLKKGLKD
>NC_006833.1|WP_136132027.1|90083_90362_-|hypothetical-protein
MELGAEVADQFLSEMNQTKIKIQDAKEATETARNVSKSFAQNAKDKNTELHDKVVNFTKKAETASENAEDFAREAFLSKQSTKTLKQETKEL
>NC_006833.1|WP_011256269.1|89237_89459_-|hypothetical-protein
MKQYTFRIDNKDPLYKKLIKLPTAYYRLKHDGNKHNIHSNNNVILEIGNNTNGVKLRWENDKIVLHKGSSALY
>NC_006833.1|WP_011256268.1|89016_89241_-|hypothetical-protein
MKNIEGQDFGVGLLFYNSGNPLTGVLKFINFYDENNLVLQKDQRRNRQALLDRGRLFSNYLHIKQGWCLCHNVW
>NC_006833.1|WP_011256279.1|99666_100944_+|proline--tRNA-ligase
MRLSQYYLPTLKEKPAHARIISHQYSLRAGLIKQIASGIYTWLPLGLRVLKNIEGIIRDEMNKSGAIEALMPCVQPASLWRESGRYDDYGKTMLRIRDRHEEDMLFGPTHEEVATDLIRDIVKSYKNLPLCLYQIQWKFRDEVRPRYGVMRGREFLMKDAYSFNVNYESALNSYNLMYKTYIKIFKRMGLIPIGVRADTGLIGGNLSHEFHILASTGESTLYYDNKFFELLESEDVKSLKSIYAVADDIHDPKTCPVPQEQLNVSKGIEIGHIFYFGDKYSKPMNAKVTAQDGKNVNIHMGSYGIGVSRLVGAIIEAFHDDKGITWPEAVAPFRVGLINLQTKTAEYVEIANKIYSTLKSDEVLYDDTEGSIGVKFAKMDLIGLPWQIIVGKKAVSENIIEIKNRATGKVEEVQIEEAINYFNVK
>NC_006833.1|WP_011256280.1|100940_101318_+|holo-[acyl-carrier-protein]-synthase
MIRGIGTDIVYIPRILRILQKYGKKFLNKIYTEQEIEISRKYNSQEMQAKYLAKRFAAKEAFVKALGGFSHGIIMKDIEIYNDVRGKPHLTVSKNFIFKDHMIHLSLSDDGDCATAFVIICSSLP
>NC_006833.1|WP_011256281.1|101340_102132_-|prolipoprotein-diacylglyceryl-transferase
MSLSPAIFSIGPVSIHWYSLAYVLGIVFAYWHLHKLDEQKIFTKNFYDSLLTATIIGIILGGRLGFVLIYDPISYINNPIEILKTWKGGMSFHGGAIGVLCAVIISCRRYNIPIFYTLDLISCGVPIGLFLGRIGNFVNGELFGRVTTMPWGMVFPESGDNLLRHPSQLYEAFFEGLLFFAIANSLFFLTRIRLYHGTLTGIAVIWYGTVRFVVEFFREPDYQVGYLWLDLTMGQLLSIFMTLLGIIVYLSALNSKFNTKSVA
>NC_006833.1|WP_011256282.1|102138_102588_-|SsrA-binding-protein-SmpB
MEVIAENRKARFEYFILEEFEAGMVLLSSEVKSLRERKVNISDAYVTEKNGEIWLHNMHIAEYKAANKKKHKPKRERKLLLHKKEINKLISQIKTAGVTIVPLSIYFNDKGLVKTRIAIVKGKKLYDKRATIKQREWNRAKSRLSKNNL
>NC_006833.1|WP_011256283.1|103117_103330_+|hypothetical-protein
MEKIENPRENIAYELVNNGSKLTNENKQKILELAKKIKKEENIASILKKSGNNAKKILTITVSFNDQEEK
>NC_006833.1|WP_158676317.1|103880_104030_+|hypothetical-protein
MKKVKKIISLTSTETADQELNTFKVSSSTGIKPCFDSGSSKGNPTDEEP
>NC_006833.1|WP_011256284.1|104273_104864_-|CvpA-family-protein
MLFDCLIIFIIVVCIIISITRGFIKELCALMFLFLSAFLTANHYDFFTINYSKYFNSKAMQNIFSTISVFIIFNLIFMIVNNWLMYILTPIRLGLIDRVTGTFVGALRGVLLSYVLFFAMHLYCYTVHDKKEEQSKIEAEDILPNWIINSYSYQALFATVEDIVDVYVPESLILKIKEIGEGMANQEKLKGDKKEE
>NC_006833.1|WP_011256285.1|104920_105517_-|riboflavin-synthase
MFKGIITNIGTIINTTIRSNSDQIFHIKAQNLSSIHEGDSIACSGVCLTVVDIINDIFTVQISQETMKVSNLGAWKVGKKINLEQAMRLSDKIDGHLVHGHVDETAKILTINQNLGSHEIKLSCPQELIKFVAKKGSVTLDGVSLTVNSVIGREFTVNIIPYTWQNTTFQYNKVNDYLNLEVDMIARYLDQLIQYKYN
>NC_006833.1|WP_011256288.1|106981_107209_-|hypothetical-protein
MHSSNDETKKKHEIDDLPKFFKEKSKEIGKAFSNKVVEISIIRSISVTSDEQEFSFKLRLLTIVDKDTHSIWILR
>NC_006833.1|WP_011256289.1|107353_108397_+|phenylalanine--tRNA-ligase-subunit-alpha
MNEELLNEIPLLEDKAVFEIESASSLQDLEKVRLSYLGRKGVIKAYFDDLRKVEDTEKKRDLGAIINVLRNKLDQLIMNKESILKAEEVNFKLQNEAIDITLPVRPEKIGRAHPLSKVMNEVKLIFAHMGFRAVNGPDIEDEFHVFDALNTPSHHPAREEQDTFYLKNKINDKRMMLRTHTSSMQIRAMKKAKTFPIKIVAAGRVYRNDFDATHTPMFHQMEGLYVNENVNMGQLKFTIHHFLNKFFGDKELKIRFRNSFFPFTEPSAEVDISYKESKWIEVLGCGIVHPNVFQNVGIDHTKYSGFAFGIGIERLAMLKYQISDLRNFYDNKISWLSHYGFHFSSLR

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NC_006833_1	1.1\|99484\|25\|NC_006833\|CRISPRCasFinder	99484-99508	25	NZ_AP014579	Burkholderia sp. RPE67 plasmid p1, complete sequence	391607-391631	4	0.84
NC_006833_1	1.1\|99484\|25\|NC_006833\|CRISPRCasFinder	99484-99508	25	MN693183	Marine virus AFVG_25M360, complete genome	20205-20229	5	0.8

1. spacer 1.1|99484|25|NC_006833|CRISPRCasFinder matches to NZ_AP014579 (Burkholderia sp. RPE67 plasmid p1, complete sequence) position: , mismatch: 4, identity: 0.84

ggaaccaccaccggtgccgcctaag	CRISPR spacer
ggaaccaccaccgttgccgccgccg	Protospacer
************* *******   *

2. spacer 1.1|99484|25|NC_006833|CRISPRCasFinder matches to MN693183 (Marine virus AFVG_25M360, complete genome) position: , mismatch: 5, identity: 0.8

ggaaccaccaccggtgccgcctaag	CRISPR spacer
cgaaccaccaccggagccgccttga	Protospacer
 ************* ******* ..

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

287110 : 299892

Cyanophage(25.0%)

tRNA

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_041571405.1\|287110_288853_-	type I secretion system permease/ATPase	W8CYL7	Bacillus_phage	2.2e-24	22.4
WP_011256418.1\|289040_290048_-\|tRNA	tRNA (adenosine(37)-N6)-threonylcarbamoyltransferase complex transferase subunit TsaD	A0A0R6PI74	Moraxella_phage	1.2e-62	40.5
WP_011256420.1\|291216_291579_-	hypothetical protein	NA	NA	NA	NA
WP_011256421.1\|291755_292364_+	superoxide dismutase	Q56AR7	Bacillus_thuringiensis_phage	1.2e-33	38.7
WP_041571407.1\|292365_293637_+	insulinase family protein	A0A2K9L1M6	Tupanvirus	4.1e-41	26.7
WP_011256423.1\|294344_294779_+	preprotein translocase subunit YajC	A0A1B1IVR5	uncultured_Mediterranean_phage	1.9e-14	48.2
WP_011256424.1\|294803_296624_+	glutamine--fructose-6-phosphate transaminase (isomerizing)	A7J689	Paramecium_bursaria_Chlorella_virus	2.3e-93	37.6
WP_158676336.1\|297348_297711_-	hypothetical protein	NA	NA	NA	NA
WP_011256426.1\|297707_298001_-	hypothetical protein	NA	NA	NA	NA
WP_041571547.1\|298134_299169_+	phosphoribosylformylglycinamidine cyclo-ligase	A0A1D7SE90	Cyanophage	5.1e-58	41.2
WP_011256428.1\|299169_299892_-	phosphoribosylaminoimidazolesuccinocarboxamide synthase	A0A1D7SPE1	Cyanophage	1.9e-38	40.3

DBSCAN-SWA_2

943957 : 1011533

Erwinia_phage(10.0%)

protease,integrase,tRNA

attL 950753:950773|attR 1013102:1013122

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_041571505.1\|943957_944512_+\|protease	ATP-dependent protease subunit HslV	NA	NA	NA	NA
WP_011256920.1\|944513_946004_+\|protease	ATP-dependent protease ATPase subunit HslU	A0A2H5BJT2	Erwinia_phage	4.2e-37	30.8
WP_011256922.1\|948159_950709_+	DNA polymerase I	A0A142F1Q9	Bacillus_phage	1.4e-56	37.4
950753:950773	attL	NA	NA	NA	NA
WP_160119453.1\|951325_952390_+	hypothetical protein	NA	NA	NA	NA
WP_011256924.1\|952384_953812_-\|protease	metalloprotease TldD	NA	NA	NA	NA
WP_050707679.1\|955268_955484_-	hypothetical protein	NA	NA	NA	NA
WP_050707680.1\|955495_955753_-	cation:dicarboxylase symporter family transporter	NA	NA	NA	NA
WP_011256925.1\|956641_957349_+	uroporphyrinogen-III synthase	NA	NA	NA	NA
WP_011256926.1\|957348_958131_+	exodeoxyribonuclease III	M1PSC0	Streptococcus_phage	6.3e-08	23.5
WP_041571506.1\|958743_959817_+	AI-2E family transporter	NA	NA	NA	NA
WP_011256928.1\|959939_960575_+	chromosomal DNA replication initiator DnaA	NA	NA	NA	NA
WP_011256929.1\|960946_961933_+\|integrase	tyrosine-type recombinase/integrase	A0A0K2CP59	Brevibacillus_phage	6.2e-29	28.3
WP_041571507.1\|961997_962711_+	1-acyl-sn-glycerol-3-phosphate acyltransferase	NA	NA	NA	NA
WP_011256931.1\|962774_963044_+	30S ribosomal protein S20	NA	NA	NA	NA
WP_011256932.1\|963109_964360_+	citrate synthase	NA	NA	NA	NA
WP_011256933.1\|965179_966118_-	FKBP-type peptidyl-prolyl cis-trans isomerase	NA	NA	NA	NA
WP_011256934.1\|966110_967028_-	polyprenyl synthetase family protein	NA	NA	NA	NA
WP_011256935.1\|967178_967445_+	acyl carrier protein	NA	NA	NA	NA
WP_011256936.1\|967451_968720_+	beta-ketoacyl-ACP synthase II	NA	NA	NA	NA
WP_011256937.1\|968817_970095_+	UDP-N-acetylglucosamine 1-carboxyvinyltransferase	NA	NA	NA	NA
WP_011256938.1\|970104_970974_+	FAD-dependent thymidylate synthase	M4QT16	Loktanella_phage	3.9e-75	50.3
WP_011256939.1\|971040_973131_-	collagenase	NA	NA	NA	NA
WP_011256941.1\|974464_974749_+	hypothetical protein	NA	NA	NA	NA
WP_158676309.1\|975642_975807_-	hypothetical protein	NA	NA	NA	NA
WP_041571508.1\|975991_978370_+	primosomal protein N'	NA	NA	NA	NA
WP_179943615.1\|978933_979533_+	recombination protein RecR	NA	NA	NA	NA
WP_158676310.1\|980831_980996_-	hypothetical protein	NA	NA	NA	NA
WP_011256944.1\|981612_982884_-	pyruvate dehydrogenase complex dihydrolipoamide acetyltransferase	NA	NA	NA	NA
WP_011256946.1\|983876_986672_-	hypothetical protein	NA	NA	NA	NA
WP_011256947.1\|986652_989007_-	type VI secretion protein	NA	NA	NA	NA
WP_011256948.1\|989037_989415_-	hypothetical protein	NA	NA	NA	NA
WP_011256949.1\|989525_990761_-	hypothetical protein	NA	NA	NA	NA
WP_011256950.1\|990872_991913_-	nitronate monooxygenase	NA	NA	NA	NA
WP_041571509.1\|991918_992440_-	cytochrome b	NA	NA	NA	NA
WP_041571510.1\|994434_995346_-	signal recognition particle-docking protein FtsY	D6PHS7	uncultured_phage	1.1e-14	36.4
WP_011256953.1\|995524_995917_+	Fe-S cluster assembly scaffold IscU	A0A218MKD1	uncultured_virus	7.2e-53	79.0
WP_011256954.1\|995923_996328_+	iron-sulfur cluster assembly accessory protein	A0A0P0CQC4	Ostreococcus_lucimarinus_virus	4.0e-14	33.9
WP_011256955.1\|996320_996776_+	molecular chaperone Hsc20	NA	NA	NA	NA
WP_011256956.1\|996753_998511_+	Fe-S protein assembly chaperone HscA	F2Y2E1	Organic_Lake_phycodnavirus	4.3e-89	36.2
WP_050707681.1\|998513_999260_-	signal peptidase I	NA	NA	NA	NA
WP_011256959.1\|999706_1000636_+	AEC family transporter	NA	NA	NA	NA
WP_041571512.1\|1000700_1002170_-\|tRNA	Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatA	NA	NA	NA	NA
WP_011256961.1\|1002820_1005199_-	DNA topoisomerase (ATP-hydrolyzing) subunit B	G3M9Z3	Bacillus_virus	7.8e-110	34.5
WP_041571513.1\|1006317_1006914_-	hypothetical protein	NA	NA	NA	NA
WP_011256963.1\|1006998_1007334_-	divalent-cation tolerance protein CutA	NA	NA	NA	NA
WP_011256964.1\|1007540_1009166_-	hypothetical protein	NA	NA	NA	NA
WP_011256965.1\|1009620_1010658_+\|protease	FtsH protease activity modulator HflK	NA	NA	NA	NA
WP_011256966.1\|1010660_1011533_+\|protease	protease modulator HflC	NA	NA	NA	NA
1013102:1013122	attR	NA	NA	NA	NA

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage