CRISPRimmunity

Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NC_000921	Helicobacter pylori J99, complete sequence	3 crisprs	cas14j,DEDDh	0	1	1	0

1. NC_000921

CRISPR-Cas detection and classification

Crispr_ID: NC_000921_1

• CRISPR_ID: NC_000921_1
• CRISPR_location: 59871-59978
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NC_000921_1

Consensus_repeat	Method
AGAAAACCTAACTAAAGAAAAAAC	CRISPRCasFinder

spacers of NC_000921_1

>1.1|59895|60|NC_000921|CRISPRCasFinder
AGAATTAAATAACAAGATTACTGGGTTAGCCACAGAAAAAGAAAGGTTAGCCGCAGACAA

CRISPR arrays and Neighbor proteins around NC_000921_1

CRISPR arrays

The CRISPR arrays of NC_000921_1

>merge|NC_000921|1|59871-59978|CRISPRCasFinder
TCAAAGGCTAACCACAGAAAAAACAGAATTAAATAACAAGATTACTGGGTTAGCCACAGAAAAAGAAAGGTTAGCCGCAGACAAAGAAAACCTAACTAAAGAAAGCAG

>NC_000921|1|1|59871-59978|CRISPRCasFinder
TCAAAGGCTAACCACAGAAAAAAC	AGAATTAAATAACAAGATTACTGGGTTAGCCACAGAAAAAGAAAGGTTAGCCGCAGACAA
AGAAAACCTAACTAAAGAAAGCAG

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_000921.1|WP_000899119.1|66646_67000_+|hypothetical-protein	unknown	unknown	unknown
NC_000921.1|WP_000378836.1|45189_46188_-|hydrogenase-expression/formation-protein-HypE	unknown	unknown	gnl|CDD|273984
NC_000921.1|WP_000536945.1|60489_61473_+|hypothetical-protein	unknown	unknown	gnl|CDD|224117
NC_000921.1|WP_160442686.1|66968_69413_+|DNA-translocase-FtsK	unknown	unknown	gnl|CDD|224588
NC_000921.1|WP_001099400.1|69486_70284_-|urease-accessory-protein-UreD	unknown	unknown	gnl|CDD|223899
NC_000921.1|WP_000357456.1|70911_71682_-|urease-accessory-protein-UreF	unknown	unknown	gnl|CDD|223900
NC_000921.1|WP_000827169.1|48439_49432_-|AguA-family-protein	unknown	unknown	gnl|CDD|225505
NC_000921.1|WP_001169408.1|54919_58477_-|aldehyde-dehydrogenase-family-protein	unknown	unknown	gnl|CDD|143443
NC_000921.1|WP_000510345.1|53402_54893_-|sodium/proline-symporter-PutP	unknown	unknown	gnl|CDD|273981
NC_000921.1|WP_000988455.1|63897_64467_+|hypothetical-protein	unknown	unknown	unknown
NC_000921.1|WP_000092092.1|64482_64743_+|hypothetical-protein	unknown	unknown	gnl|CDD|377587
NC_000921.1|WP_041925870.1|46190_48443_-|carbamoyltransferase-HypF	unknown	unknown	gnl|CDD|272929
NC_000921.1|WP_000614628.1|49490_50183_-|site-specific-DNA-methyltransferase	unknown	unknown	gnl|CDD|334588
NC_000921.1|WP_000375120.1|66225_66645_+|SMI1/KNR4-family-protein	unknown	unknown	gnl|CDD|378155
NC_000921.1|WP_010882488.1|50160_50718_-|DNA-cytosine-methyltransferase	unknown	unknown	gnl|CDD|223348
NC_000921.1|WP_000852783.1|64753_66256_+|5-amino-6-(5-phosphoribosylamino)uracil-reductase	unknown	unknown	gnl|CDD|379604
NC_000921.1|WP_000238747.1|70283_70883_-|urease-accessory-protein-UreG	unknown	unknown	gnl|CDD|129208
NC_000921.1|WP_000848997.1|58797_59007_+|hypothetical-protein	unknown	unknown	unknown
NC_000921.1|WP_001874436.1|52192_52975_-|type-II-restriction-endonuclease	unknown	unknown	gnl|CDD|368834
NC_000921.1|WP_001180464.1|51151_52183_-|site-specific-DNA-methyltransferase	unknown	unknown	gnl|CDD|225100

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_000921.1|WP_001099400.1|69486_70284_-|urease-accessory-protein-UreD	gnl|CDD|223899	COG0829, UreH, Urease accessory protein UreH [Posttranslational modification, protein turnover, chaperones].	3.7649e-105
NC_000921.1|WP_000378836.1|45189_46188_-|hydrogenase-expression/formation-protein-HypE	gnl|CDD|273984	TIGR02124, Hydrogenase_expression/formation_protein_HypE, hydrogenase expression/formation protein HypE. This family contains HypE (or HupE), a protein required for expression of catalytically active hydrogenase in many systems. It appears to be an accessory protein involved in maturation rather than a regulatory protein involved in expression. HypE shows considerable homology to the thiamine-monophosphate kinase ThiL (TIGR01379) and other enzymes.	5.36283e-176
NC_000921.1|WP_000536945.1|60489_61473_+|hypothetical-protein	gnl|CDD|224117	COG1196, Smc, Chromosome segregation ATPases [Cell division and chromosome partitioning].	2.64912e-16
NC_000921.1|WP_160442686.1|66968_69413_+|DNA-translocase-FtsK	gnl|CDD|224588	COG1674, FtsK, DNA segregation ATPase FtsK/SpoIIIE and related proteins [Cell division and chromosome partitioning].	8.57336e-122
NC_000921.1|WP_000357456.1|70911_71682_-|urease-accessory-protein-UreF	gnl|CDD|223900	COG0830, UreF, Urease accessory protein UreF [Posttranslational modification, protein turnover, chaperones].	3.15336e-94
NC_000921.1|WP_000827169.1|48439_49432_-|AguA-family-protein	gnl|CDD|225505	COG2957, COG2957, Peptidylarginine deiminase and related enzymes [Amino acid transport and metabolism].	0
NC_000921.1|WP_001169408.1|54919_58477_-|aldehyde-dehydrogenase-family-protein	gnl|CDD|143443	cd07125, ALDH_PutA-P5CDH, Delta(1)-pyrroline-5-carboxylate dehydrogenase, PutA. The proline catabolic enzymes of the aldehyde dehydrogenase (ALDH) protein superfamily, proline dehydrogenase and Delta(1)-pyrroline-5-carboxylate dehydrogenase (P5CDH, (EC=1.5.1.12 )), catalyze the two-step oxidation of proline to glutamate; P5CDH catalyzes the oxidation of glutamate semialdehyde, utilizing NAD+ as the electron acceptor. In some bacteria, the two enzymes are fused into the bifunctional flavoenzyme, proline utilization A (PutA) These enzymes play important roles in cellular redox control, superoxide generation, and apoptosis. In certain prokaryotes such as Escherichia coli, PutA is also a transcriptional repressor of the proline utilization genes.	0
NC_000921.1|WP_000510345.1|53402_54893_-|sodium/proline-symporter-PutP	gnl|CDD|273981	TIGR02121, Osmoregulated_proline_transporter, sodium/proline symporter. This family consists of the sodium/proline symporter (proline permease) from a number of Gram-negative and Gram-positive bacteria and from the archaeal genus Methanosarcina. Using the related pantothenate permease as an outgroup, candidate sequences from Bifidobacterium longum and several from archaea are found to be outside the clade defined by known proline permeases. These sequences, scoring between 570 and -40, define the range between trusted and noise cutoff scores. [Transport and binding proteins, Amino acids, peptides and amines].	0
NC_000921.1|WP_000092092.1|64482_64743_+|hypothetical-protein	gnl|CDD|377587	pfam06013, WXG100, Proteins of 100 residues with WXG. ESAT-6 is a small protein appears to be of fundamental importance in virulence and protective immunity in Mycobacterium tuberculosis. homologs have been detected in other Gram-positive bacterial species. It may represent a novel secretion system potentially driven by the pfam01580 domains in the YukA-like proteins.	0.000968589
NC_000921.1|WP_000614628.1|49490_50183_-|site-specific-DNA-methyltransferase	gnl|CDD|334588	pfam01555, N6_N4_Mtase, DNA methylase. Members of this family are DNA methylases. The family contains both N-4 cytosine-specific DNA methylases and N-6 Adenine-specific DNA methylases.	1.7131e-55
NC_000921.1|WP_000375120.1|66225_66645_+|SMI1/KNR4-family-protein	gnl|CDD|378155	pfam09346, SMI1_KNR4, SMI1 / KNR4 family (SUKH-1). Proteins in this family are involved in the regulation of 1,3-beta-glucan synthase activity and cell-wall formation. Genome contextual information showed that SMI1 are primary immunity proteins in bacterial toxin systems.	2.79096e-08
NC_000921.1|WP_010882488.1|50160_50718_-|DNA-cytosine-methyltransferase	gnl|CDD|223348	COG0270, Dcm, Site-specific DNA methylase [DNA replication, recombination, and repair].	4.68169e-19
NC_000921.1|WP_000852783.1|64753_66256_+|5-amino-6-(5-phosphoribosylamino)uracil-reductase	gnl|CDD|379604	pfam14414, WHH, A nuclease of the HNH/ENDO VII superfamily with conserved WHH. WHH is a predicted nuclease of the HNH/ENDO VII superfamily of the treble clef fold. The name is derived from the conserved motif WHH. It is found in bacterial polymorphic toxin systems and functions as a toxin module. WHH is the shortest version of HNH nuclease families. Like AHH and LHH, the WHH nuclease contains 4 conserved histidines of which the first one is predicted to bind a metal-ion and other three ones are involved in activation of water molecule for hydrolysis.	1.07832e-09
NC_000921.1|WP_000238747.1|70283_70883_-|urease-accessory-protein-UreG	gnl|CDD|129208	TIGR00101, Urease_accessory_protein_UreG, urease accessory protein UreG. This model represents UreG, a GTP hydrolase that acts in the assembly of the nickel metallocenter of urease. It is found only in urease-positive species, although some urease-positive species (e.g. Bacillus subtilis) lack this protein. A similar protein, hypB, is an accessory protein for expression of hydrogenase, which also uses nickel. [Central intermediary metabolism, Nitrogen metabolism].	2.71579e-140
NC_000921.1|WP_041925870.1|46190_48443_-|carbamoyltransferase-HypF	gnl|CDD|272929	TIGR00143, Carbamoyltransferase_HypF, [NiFe] hydrogenase maturation protein HypF. A previously described regulatory effect of HypF mutatation is attributable to loss of activity of a regulatory hydrogenase. A zinc finger-like region CXXCX(18)CXXCX(24)CXXCX(18)CXXC region further supported the regulatory hypothesis. However, more recent work (PUBMED:11375153) shows the direct effect is on the activity of expressed hydrogenases with nickel/iron centers, rather than on expression. [Protein fate, Protein modification and repair].	0
NC_000921.1|WP_001874436.1|52192_52975_-|type-II-restriction-endonuclease	gnl|CDD|368834	pfam06300, Tsp45I, Tsp45I type II restriction enzyme. This family consists of several type II restriction enzymes.	4.08234e-138
NC_000921.1|WP_001180464.1|51151_52183_-|site-specific-DNA-methyltransferase	gnl|CDD|225100	COG2189, COG2189, Adenine specific DNA methylase Mod [DNA replication, recombination, and repair].	2.30604e-48

Protein sequences

>NC_000921.1|WP_000848997.1|58797_59007_+|hypothetical-protein
MKTIKNGIMIGTLGALLLSGCSSFDAQRFACLPKDHSSKDASTKKEAQYIPKGFFDPYSSNLNHWDSTF
>NC_000921.1|WP_001169408.1|54919_58477_-|aldehyde-dehydrogenase-family-protein
MQKIIEDSLELAKKLQDSISNHLSEQEKAFHFKMQKLLNNPENKVMLIELMDRSFRCLDNKARFEMIEHVLDKYKSREIFSSFEKWLLMGFLSFGKMLPDMSVPFFVNKIRSDTKAMVLDQEESQLRERILKRKNEKIILNVNFIGEEVLGEEEASARFEKYSQALKSNYIQYISIKITTIFSQINILDFEYSKKEIVKRLDALYALALEEEKKQGMPKFINLDMEEFRDLELTVESFMESIAKFDLNAGIVLQAYIPDSYEYLKKLHAFSKERVLKGLKPIKIRFVKGANMESEETIASMKDWALPTFSSKQDTDSNYNKMLDFVLEGDNYKYIHIGAASHNIFEIAYVYTRIHALNDPVVLEHFSFEMLEGMSLQASQELKEMHKLILYAPVCDEAHFNNAIAYLVRRLDENTSSDNFMKAFFNLKVGTSEWKDQEQRFLNSLKGIATLDNTTHRTQDRNAKQTGHTTYPNHSFKNESDTDFILKANREWAKKVRDKMHNAPILELYPEIDGRFEDPNLTPLEVFDRIHHKKIASVHLADKEAILKALEVAKSDKSRFSQKSFTEIHALLSQTAQLFRERRGDLIGISALEVGKTFAETDAEVSEAIDFLEFYPYSLRVLQEQNKKTKFTPKGVGVVIAPWNFPVGISVGTIAAPLAAGNRVIYKPSSLSSVTGYKLCECFWDAGVPRDALIYLPSKGSDISEHLLKDESIKFAILTGGEDTAYKMLKANPTLALSAETGGKNATIVSKMADRDQAIKNVIHSAFSNSGQKCSATSLLVLEKEVYEDENFKKTLIDATLSLSVGDPFDFKNKIGALADKPNEKVIKAIDELKSYENYEIPASFVDDNPYLMKPSIKYGTKKGDFTHQTELFTPILSVMKAKDLDEAIEIVNSTGYGLTSALESLDEREWEYYLERIEAGNIYINKPTTGAIVLRQPFGGVKKSAVGFGRKVGIFNYITQFVNIHQEEEDENALKNPLSEALEGLTQKGYDEHTHELKRAIFMAKSYAYHYKHEFSQAKDYVKIRGEDNLFSYTKVTSVGYRITEKDTLSDMLGVALACLISQIPLTISIENERANKDLTFFLECLKALQANAPIVYESLQKFSEKLNAFNRVRYLKSDLDLLHEQASRLGMVLATAKPCLNGRFELLYYHLERSVSISYHRYGNLGSRVLRQPTCHKSCCAEK
>NC_000921.1|WP_000510345.1|53402_54893_-|sodium/proline-symporter-PutP
MGHVVLSTPIVTMFVVYSLLMLYIGFYFYKQNETTEDYFLGDRSMGPVISALSAGASDMSGWLLMGLPGALYVGGLINSHIAIGLSLGALINWVFVAKRLRIYTSVIANSITISDYFETRFSDDKHILRLISAFVILIFFIFYISSGLVSGAKLFEATFGIQYTYALSIGTLIIVSYTFLGGYKAVCWTDLIQGLLMMSALIVVPIVMIIHLGGIGEGIKIIREIKPENLSFLQGSSVVAIISSLAWGLGYFGQPHILVRFMSIRSIRDVPKATTIGISWMVISLIGACVMGLLGVAYVHKFDLSLEDPEKIFIVMSQLLFNPWITGILLSAILAAVMSTASSQLLVSSSTIAEDFYATIFNKNAPQKLVMTISRLSVLGVACIAFFISTDKNASILSIVSYAWAGFGASFGSVILFSLFWSRMTRIGAIAGMLSGASTVILYDKFGKSFLDIYEIVPGFIVASVAIVAFSLFSSVRSGTKEAFETMLKEIESLKH
>NC_000921.1|WP_001874436.1|52192_52975_-|type-II-restriction-endonuclease
MNYWTKLSIEYANQRSYLDDLFQVYPTIPEGLREIDSKIWSNVEYHFKRKDNLALITELLNLDLFPIKDSYMAYLKRDKSALERNPRTINRICGRLYEMGLNKIFEKCSEPKETNRQIGPMFKDWINNKSLGVEPVDLNDFIANENDAILKASDNVMAEFAKSHLNYHHHKGLDFVARFNKKYIIGEAKFLTDFGGHQNAQFNDAINTIETPNIKAIKVAILDGVLYIESNNKMRKLLDTTYRNYHIMSALVLREFLYQI
>NC_000921.1|WP_001180464.1|51151_52183_-|site-specific-DNA-methyltransferase
MQNLLIQAENAIALLFLLNDKNLKGKIDLIYIDPPFATNNHFTITNGRATTISNSKNGDIAYSDKVVGMDFMEFLKQRLVLLKELLSEQGSIYVHTDYKIGHYVKVMLDEIFGIQNFRNEITRIKCNPKNFKRIGYGNIKDMILFYSKGKNPIFNEPKIPYTPQDLEKRFPKIDKDKRRYTTVPIHAPGEVESGECSKAFKGMLPPKGRHWRTDIATLERWDKEGLIEYSNNNNPRKKIYALEQVGKRVQDIWEFKDPQYPSYPTEKNAQLLDLIIKTSSNKDSIVLDCFCGSGTTLKSAFLLQRKFIGIDNSDLAIQACKNKLETITKDLFVSQNFYDFLVF
>NC_000921.1|WP_010882488.1|50160_50718_-|DNA-cytosine-methyltransferase
MLVSRFLNAIDPFNLGVLLSRFQIKNGCIYGVCSYKVSKFTPGYEESKARVLNALNILSKHQIWQSNQESVTKVKGTFVFILENDLHLDENSFYKKLLNLIIDNDFFNRSHLVTPSNGTNSHPELHRSITPREAARIQSFSDDYIFYGNKTSVCKQIGNAVPPLLALALGKAILKSARNDTNPSR
>NC_000921.1|WP_000614628.1|49490_50183_-|site-specific-DNA-methyltransferase
MIQIHHANAFEIIKDFHQQNLKVDAIITDPPYNISVKNNFSTLKSAKRQGIDFGEWDKNFKLLEWIARYASLINPNGCMVIFCSYRFISYIADFLEENGFVVKDFIQWVKNNPMPRNIHRRYVQDTEFALWAVKKKAKWVFNKPKNEKYLRPLILKSPVVSGIERVKHPTQKSLTLMEKIISTHTNPNDTVLDPFMGSGTTGLACKNLKRNFIGIESEKEYFQIAQKRLS
>NC_000921.1|WP_000827169.1|48439_49432_-|AguA-family-protein
MKRMLAEFEKIQAILMAFPHEFGDWAYCIEEARESFLHIIQTIAKHAKVLVCVHTNDTIGYETLKNLPGVEIARIDTNDTWARDFGAISVENHGVLECLDFGFNGWGLKYPSNLDNQVNFKLKHLGFLKHPLKTMPYILEGGSIESDGAGSILTNTQCLLEKNRNPHLNQNGIETMLKKELGAKQVLWYSYGYLKGDDTDSHTDTLARFLNKDTIVYSACEDENDEHYTALKKMQEELKTFKKLDGTPYKLIPLEIPKAVYNENQQRLPATYVNFLLCNNALIVPTYNDPNDTLILETLRQHTPLEVIGVDCNTLIKQHGSLHCVTMQLY
>NC_000921.1|WP_041925870.1|46190_48443_-|carbamoyltransferase-HypF
MNKITLFGVVQGVGMRPFVYILAQKLGLVGFVRNAQAALEIVLPAHKTESFLNALKKGLPPLALVEKIIISPYDKALHFNDFRILESKNHPLNLLSQIPKDLGVCEDCLCEIRDKNSPYFHYAFNSCAKCGARYSLLNAMPYDRENSALKPFKLCKFCASVYKDAHNKRFHIQGISCKKCGIALNYKRFKNDDALLECAKDIQKGKIIALKGLGGFALLCDARNFKTIERLRLLKNRPLKPFALMFKDLNAAKQHAFLNALECESLNSVSAPILLARKKPDTQLAPNIAKNSPFYGVILPYTPLHALLLDLLDSPIVFTSANFSSLPLASDEKEIDSLHFIFDFKLTHNRTIIHRIDDSIAQRVDNAIRPMRLVRGFAPLYLTLPKRSFNAPKKILALGAEQKGHFSLLDSETSVLLLSPFCGDLSVLENEKHFKETLNFFLKTYDFKPTLLACDEHQNYTTTKMAFDFNTPLLQVQHHHAHFLASVLDALLQDPHLNHPFIGIVWDGSGAYENKIYGAECFVGDLERIEEVARFEEFWLLGGQKAIKEPRRLVLEIALKHQLNKLLKRVQKHFKEDELGIFKQMHDKKIQSVATNSIGRLFDIVAFSLGVVGTISFEAESGQVLENLALQSDEIAFYPFEIKNSVVRLKEFYQAFEKDLGVLEPKRIAKKFFNSLVEIITALIAPFKGHVVVCSGGVFCNQLLCEQLAKRLKKLQREYFFHKHFPPNDSSIPVGQALMAYFNPTIIKKG
>NC_000921.1|WP_000378836.1|45189_46188_-|hydrogenase-expression/formation-protein-HypE
MDSVTLACGNGGKETNALIERVFMPYLKEWIVAFDEDAPKFEASGEYCVSTDSFVITPLIFNGGDIGKLCVCGSANDVSVQGGEPLYLNMGFILEEGLEIPLLKQILQSIQKELFKANLKLLSLDTKVVPKGSVDKLFINTTCIGKIIKPGISSRHLQQGQAIILSDTIANHGASLFATRHEIKLKTNLQSDCQLLYPLLKPLFLSDLKIDALRDATRGGLASVLNEWANSSRVKIVIEEEKIPLKEETKGICEILGLEPYALANEGVFVLALNQKDAPKALEILKSNEKAKNACVIGGVFENPYPSVVLKNAWGFERILEMPEGELLPRIC
>NC_000921.1|WP_000536945.1|60489_61473_+|hypothetical-protein
MGTLIEKWFGFSQIREELEARISELEDENTELLREREYLAAETSELKDANDQLRQKNDKLFITKDKLTKENTELFAENESLSVKISGLEHSNDQLWQNNNKLTKEKAELKTEKDILAKENTRLLAARDRLTEEKRELTTEKERLKRENTELTHKITELTKENKALTTENDKLNHQVTALTNERDSLEQERARLQDAHGFLEKRCTNLEKENQRLTDKLKQLESAQKSLENTNNQLRQALENSNVQLAQAKEKIAIEKSELEREIARLKSLEGMEAKSDLDLHNRRLASANEDLKRQNRKLEEENIALKERVDGLNEQLSKLQPQKPQ
>NC_000921.1|WP_000988455.1|63897_64467_+|hypothetical-protein
MMTKNAYAFVVIEKSIMVFKCAKDKGLIPITEGFVPLKEGFLRSFKERCNLDFLENLDLLFLYDYQFPSEVFSLCKDLKNSIWDRKLVVVLVEALEGFKGLNLSLKIEDRHSNSLGNGVQKLLTNADLGSNHKPIVIDSMKTYHQSQQEKYKRERGETLEVRPTTPPSYGGGSIRISGDKKPDSNEENF
>NC_000921.1|WP_000092092.1|64482_64743_+|hypothetical-protein
MSRVQMDTEEVREFVGHLERFKELLNEEVNSLNGHFHNLESWQDARRDKFSEVLDNLKGTFNEFNEAAQEQIAWLKERIRVLEEDY
>NC_000921.1|WP_000852783.1|64753_66256_+|5-amino-6-(5-phosphoribosylamino)uracil-reductase
MAEWKTDTEEVKKVVGRCREFKRSLQEEKCSPFIKDLDSYALKIIVERRKTEMQLEKAIGELKKAKSNEDDAKVALRVLQGASVVSWIWPPARIAATAAIVAAEAVLKFMKEDTEKCKRNVELLERMLEIYSNQAKASANLMNQAWEGIKKRLHFYTDKHQEFIRRLKQASDAIDNEYNFPTPGVLLEYDFERPAISYTPKKSVFNERLKDLRENFSASLYADLKDKIHHNALSNDDLERMIAFREQEFEKSLEDWMGAYSYDENPNDELDRMAISKEQELEKSLEDLMPSVLGVPSYNESLTLAKNRCVKNFKEALEGFTEKIKESPNDSNAINEAFDNLETELERATENLSQKIDPVLERNENYTQKALEYREFLESRKESFIVDEKNPYPEEVSFNEWRWAEFDSVFSAIVPLEDLNKTACAHHALKALQATLKDNDLGFDATELEQIAKGFIPRGYLWHFDANVLGNLALVREELLLGVKHTKGYSLWTEFLQKQN
>NC_000921.1|WP_000375120.1|66225_66645_+|SMI1/KNR4-family-protein
MDRISTETELNWEFVESLNENALSDLEERLEIGFSDAFKDFIKRSNYGFSQLRYFMVGNESYMFKHVLNFNLESLLIDFMQSLKEWLEPEEIVFANDGYGGYYLWNTTTDVVLFLDTDNGSKKVLLNLNMFLKKLESRG
>NC_000921.1|WP_000899119.1|66646_67000_+|hypothetical-protein
MLFSHKVFLEGCTNELRRICDSFVEGAMQDDLGQKLKSEALENMLKIAHDLENLEQETQYEMRKINEQLEEAKRLEKQVDMQDRHSQSEIDRLMREAKEHEREAKRRYGEYLKDKND
>NC_000921.1|WP_160442686.1|66968_69413_+|DNA-translocase-FtsK
MVNILRIKMIEISEWLQKLDDALDKVVAKKEPESFLKPIISPIEDYQKSVRQIQAQFTDAPKFNEEGAYPQFLSCGLLQVRGKNGANMEFLLPKVYPFPPKSLYIEHEKDGQFLREMLMRLLSSAPLVQLEVILIDALSLGGIFNLARRLLDKNNDFIYQQRILTESKEIEEALKHLHEYLKVNLQEKLAGFRDFVHYNENAKDSLPLKALFLSGVDALSKDALYYLEKIMRFGSKNGVLSFVNLESEKNNQSAEDLKRYAEFFKDRTSFECLKYLNVEIISDQGIKSQHMQDFADKIKAYYKQKKEVKRELKDLQRDKEFWTKSSQHEVSVPVGWDINHKEVCFKIGNEQNHTLICDHSGSGKSNFLHVLIQNLAFYYDPDEVQLFLLDYKEGVEFNAYVADPALEHARLVSVASSISYGITFLKWLCDEMQKRADRFKQFNVKDLSDYRKHEKMPRLIVVIDEFQVLFSDNKSTKAVEGHLNTLLKKGRSYGVHLVLATQTMRGTDINPSFKAQIANRIALPMDAEDSSSVLGDDAACEIQKPEGIFNNNGGNRKYHTKMSVPKAPDDFKSFLTKIHAEFNQRNLAPIDRKIYNGETPLKMPDTLKANEMRLHLGKKVDYEQKDLIVEFESNESHLLVVIQDLNARIALMKLLFQNVKSANKELVFCNKEKRLIRSFDAQKEYGITPVENILSVLDTAMNPNSALVIDNLNEAKELHDKVGAEKLKSFLEKAIDNEQYCVIFAHDFRQIKTNYHFDKLKELLNNHFKQCLAFRCNGENLNAIKSDLPPPSKLNVLLIELSKDSVTEFRPFSL
>NC_000921.1|WP_001099400.1|69486_70284_-|urease-accessory-protein-UreD
MNTYAQESKLRLKTKIGADGRCVIEDNFFTPPFKLMAPFYPKDDLAEIMLLAVSPGLMKGDAQDMQLNIGPNCKLRITSQSFEKIHNTEDGFASRDMHIVVGENAFLDFAPFPLIPFENAHFKGNTTISLRSSSQLLYSEIIVAGRVARNELFKFNRLHTKISILQDEKPIYYDNTILDPKTTNMNNMCMFDGYTHYLNLVLVNCPIELSGARELIEESEGVDGAVSKIASSHLCLKALAKGSEPLLHLREKIARLVTQTTTQKV
>NC_000921.1|WP_000238747.1|70283_70883_-|urease-accessory-protein-UreG
MVKIGVCGPVGSGKTALIEALTRHMSKDYDMAVITNDIYTKEDAEFMCKNSVMPRDRIIGVETGGCPHTAIREDASMNLEAVEEMHGRFPNLELLLIESGGDNLSATFNPELADFTIFVIDVAEGDKIPRKGGPGITRSDLLVINKIDLAPYVGADLKVMERDSKKMRGEKPFIFTNIRAKEGLDDVIAWIKRNALLED
>NC_000921.1|WP_000357456.1|70911_71682_-|urease-accessory-protein-UreF
MDKGKSVKSTKKSVGMPPKTPKTDNNANSHVDNEFLILQVNDAVFPIGSYTHSFGLETYIQQKKVTNKESALEYLKANLSSQFLYTEMLSLKLTYESTLQQDLKKILGIEEVIMLSTSPMELRLANQKLGNRFIKTLQAMNELDMGAFFNAYAQTTKDPTHATSYGVFAASLNMELKKALRHYLYAQTSNMVINCVKSVPLSQNDGQKILLSLQSPFNQLIEKTLELDESHLCAASVQNDIKAMQHESLYSRLYMS

Crispr_ID: NC_000921_2

• CRISPR_ID: NC_000921_2
• CRISPR_location: 82182-82288
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NC_000921_2

Consensus_repeat	Method
AACGACGACATGGGTAATAGCAACGA	CRISPRCasFinder

spacers of NC_000921_2

>2.1|82208|55|NC_000921|CRISPRCasFinder
CGACATGGGTAATAGCAACGACATGGGCGATGACATGAATAACGCGAACGACATG

CRISPR arrays and Neighbor proteins around NC_000921_2

CRISPR arrays

The CRISPR arrays of NC_000921_2

>merge|NC_000921|2|82182-82288|CRISPRCasFinder
AACGATGATACGGGTAACACTAACGACGACATGGGTAATAGCAACGACATGGGCGATGACATGAATAACGCGAACGACATGAACGACGACATGGGTAACAGCAACGA

>NC_000921|2|2|82182-82288|CRISPRCasFinder
AACGATGATACGGGTAACACTAACGA	CGACATGGGTAATAGCAACGACATGGGCGATGACATGAATAACGCGAACGACATG
AACGACGACATGGGTAACAGCAACGA

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_000921.1|WP_000901274.1|72219_72807_-|acid-activated-urea-channel	unknown	unknown	gnl|CDD|259831
NC_000921.1|WP_000688418.1|76298_77636_-|phosphoglucosamine-mutase	unknown	unknown	gnl|CDD|184621
NC_000921.1|WP_000061443.1|86328_87681_-|FAD-dependent-oxidoreductase	unknown	unknown	gnl|CDD|240393
NC_000921.1|WP_000724295.1|73030_74740_-|urease-subunit-beta	unknown	unknown	gnl|CDD|184438
NC_000921.1|WP_001199062.1|92101_93031_-|ACP-S-malonyltransferase	unknown	unknown	gnl|CDD|272922
NC_000921.1|WP_000167675.1|85356_85782_-|50S-ribosomal-protein-L13	unknown	unknown	gnl|CDD|181703
NC_000921.1|WP_001273627.1|77725_77995_+|30S-ribosomal-protein-S20	unknown	unknown	gnl|CDD|178943
NC_000921.1|WP_001918721.1|93457_93676_+|hypothetical-protein	unknown	unknown	gnl|CDD|377384
NC_000921.1|WP_000583091.1|71705_72218_-|urease-accessory-protein-UreE	unknown	unknown	gnl|CDD|237322
NC_000921.1|WP_000935478.1|75813_76305_-|lipoprotein-signal-peptidase	unknown	unknown	gnl|CDD|234739
NC_000921.1|WP_001168427.1|86133_86322_-|DUF5408-family-protein	unknown	unknown	gnl|CDD|340117
NC_000921.1|WP_000250152.1|91395_92091_-|aminodeoxyfutalosine-nucleosidase	unknown	unknown	gnl|CDD|180148
NC_000921.1|WP_000779233.1|74743_75460_-|urease-subunit-alpha	unknown	unknown	gnl|CDD|184439
NC_000921.1|WP_000357456.1|70911_71682_-|urease-accessory-protein-UreF	unknown	unknown	gnl|CDD|223900
NC_000921.1|WP_000025168.1|78113_79172_+|peptide-chain-release-factor-1	unknown	unknown	gnl|CDD|234801
NC_000921.1|WP_160442684.1|89127_91200_-|RNA-polymerase-sigma-factor-RpoD	unknown	unknown	gnl|CDD|235549
NC_000921.1|WP_000719120.1|79585_80353_+|outer-membrane-protein	unknown	unknown	gnl|CDD|280099
NC_000921.1|WP_000843375.1|82799_84821_-|methyl-accepting-chemotaxis-protein	unknown	unknown	gnl|CDD|214599
NC_000921.1|WP_001227269.1|84970_85360_-|30S-ribosomal-protein-S9	unknown	unknown	gnl|CDD|178888
NC_000921.1|WP_001268623.1|87734_89108_-|hypothetical-protein	unknown	unknown	gnl|CDD|366353

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_000921.1|WP_000901274.1|72219_72807_-|acid-activated-urea-channel	gnl|CDD|259831	cd13404, UreI_AmiS_like, UreI/AmiS family, proton-gated urea channel and putative amide transporters. This family includes UreI proton-gated urea channels as well as putative amide transporters (AmiS of the amidase gene cluster). Helicobacter pylori UreI (HpUreI), a proton-gated inner membrane urea channel opens in acidic pH to allow urea influx to the cytoplasm. There urea is metabolized, producing NH3 and CO2, leading to buffering of the periplasm. This action is essential for the survival of H. pylori in the stomach, and has been identified as a mechanism that could be clinically targeted to prevent various illnesses associated with infection by H. pylori. UreI and the related amide channels (AmiS) appear to function as hexamers, and have 6 predicted transmembrane segments. UreI has also been shown have a lipid "plug" in the center of the hexamer. Urea enters at the periplasmic opening of UreI and must pass 2 constriction sites, one on each side of a conserved Glu (Glu 177, H. pylori numbering), to reach the cytoplasm. Urea/thiourea selectivity is diminished by mutation of a conserved Trp to Ala or Phe in constriction site 2 (cytoplasmic). Channel functionality is greatly diminished by mutation of a conserved Trp in constriction site 1 (periplasmic) and a conserved Tyr in constriction site 2, and to a lesser extent a conserved Phe in site 1. In the cytoplasm, urease hydrolyzes urea to form ammonia and carbamate, which decomposes to carbonic acid. UreI is fully open at pH 5.0 to facilitate urea influx, but closes at neutral pH, preventing over-alkalization. Glu 177 (H. pylori numbering) is present in urea channel proteins, but absent in the related amide channels, suggesting that it plays a role in urea specificity.	5.78484e-75
NC_000921.1|WP_000688418.1|76298_77636_-|phosphoglucosamine-mutase	gnl|CDD|184621	PRK14324, glmM, phosphoglucosamine mutase; Provisional.	0
NC_000921.1|WP_000061443.1|86328_87681_-|FAD-dependent-oxidoreductase	gnl|CDD|240393	PTZ00383, PTZ00383, malate:quinone oxidoreductase; Provisional.	1.52311e-172
NC_000921.1|WP_000724295.1|73030_74740_-|urease-subunit-beta	gnl|CDD|184438	PRK13985, ureB, urease subunit alpha.	0
NC_000921.1|WP_001199062.1|92101_93031_-|ACP-S-malonyltransferase	gnl|CDD|272922	TIGR00128, Malonyl_CoA-acyl_carrier_protein_transacylase, malonyl CoA-acyl carrier protein transacylase. This enzyme of fatty acid biosynthesis transfers the malonyl moeity from coenzyme A to acyl-carrier protein. The seed alignment for this family of proteins contains a single member each from a number of bacterial species but also an additional pair of closely related, uncharacterized proteins from B. subtilis, one of which has a long C-terminal extension. [Fatty acid and phospholipid metabolism, Biosynthesis].	2.47495e-149
NC_000921.1|WP_000167675.1|85356_85782_-|50S-ribosomal-protein-L13	gnl|CDD|181703	PRK09216, rplM, 50S ribosomal protein L13; Reviewed.	2.62572e-78
NC_000921.1|WP_001273627.1|77725_77995_+|30S-ribosomal-protein-S20	gnl|CDD|178943	PRK00239, rpsT, 30S ribosomal protein S20; Reviewed.	9.45572e-24
NC_000921.1|WP_001918721.1|93457_93676_+|hypothetical-protein	gnl|CDD|377384	pfam04556, DpnII, DpnII restriction endonuclease. Members of this family are type II restriction enzymes (EC:3.1.21.4). They recognize the double-stranded unmethylated sequence GATC and cleave before G-1. http://rebase.neb.com/rebase/enz/DpnII.html.	6.63712e-15
NC_000921.1|WP_000583091.1|71705_72218_-|urease-accessory-protein-UreE	gnl|CDD|237322	PRK13261, ureE, urease accessory protein UreE; Provisional.	1.12528e-46
NC_000921.1|WP_000935478.1|75813_76305_-|lipoprotein-signal-peptidase	gnl|CDD|234739	PRK00376, lspA, lipoprotein signal peptidase.	1.87012e-41
NC_000921.1|WP_001168427.1|86133_86322_-|DUF5408-family-protein	gnl|CDD|340117	pfam17402, DUF5408, Family of unknown function (DUF5408). This is a family of unknown function found in Helicobacteraceae. Family members are predicted to contain one trans-membrane region.	3.07569e-07
NC_000921.1|WP_000250152.1|91395_92091_-|aminodeoxyfutalosine-nucleosidase	gnl|CDD|180148	PRK05584, PRK05584, 5'-methylthioadenosine/adenosylhomocysteine nucleosidase.	7.93452e-115
NC_000921.1|WP_000779233.1|74743_75460_-|urease-subunit-alpha	gnl|CDD|184439	PRK13986, PRK13986, urease subunit beta.	4.7279e-143
NC_000921.1|WP_000357456.1|70911_71682_-|urease-accessory-protein-UreF	gnl|CDD|223900	COG0830, UreF, Urease accessory protein UreF [Posttranslational modification, protein turnover, chaperones].	3.15336e-94
NC_000921.1|WP_000025168.1|78113_79172_+|peptide-chain-release-factor-1	gnl|CDD|234801	PRK00591, prfA, peptide chain release factor 1; Validated.	0
NC_000921.1|WP_160442684.1|89127_91200_-|RNA-polymerase-sigma-factor-RpoD	gnl|CDD|235549	PRK05658, PRK05658, RNA polymerase sigma factor RpoD; Validated.	0
NC_000921.1|WP_000719120.1|79585_80353_+|outer-membrane-protein	gnl|CDD|280099	pfam01856, HP_OMP, Helicobacter outer membrane protein. This family seems confined to Helicobacter. It is predicted to be an outer membrane protein based on its pattern of alternating hydrophobic amino acids similar to porins.	4.79329e-42
NC_000921.1|WP_000843375.1|82799_84821_-|methyl-accepting-chemotaxis-protein	gnl|CDD|214599	smart00283, MA, Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). Thought to undergo reversible methylation in response to attractants or repellants during bacterial chemotaxis.	5.84701e-36
NC_000921.1|WP_001227269.1|84970_85360_-|30S-ribosomal-protein-S9	gnl|CDD|178888	PRK00132, rpsI, 30S ribosomal protein S9; Reviewed.	8.38483e-68
NC_000921.1|WP_001268623.1|87734_89108_-|hypothetical-protein	gnl|CDD|366353	pfam00877, NLPC_P60, NlpC/P60 family. The function of this domain is unknown. It is found in several lipoproteins.	1.45251e-18

Protein sequences

>NC_000921.1|WP_000719120.1|79585_80353_+|outer-membrane-protein
MKKIFLGMALAFSVSMAEKSGAFLGGGFQYSNLENQNTTRTPSANNNTPINTSMFGNNQAAPAQETPSVINTNNYGQMYGVDAMAGYKWFFGKTKRFGFRTYGYYSYNHANLSFVGSKLGIMDGASQVNNFTYGVGFDALYNFYESKEGYNTAGLFVGFGLGGDSFIVQGESYLKSQMQICNNTAGCSASMNTSYFQMPVEFGFRSNFSKHSGIEVGFKLPLFTNQFYKERGVDGSVDVFYKRNFSIYFNYMINL
>NC_000921.1|WP_000025168.1|78113_79172_+|peptide-chain-release-factor-1
MSILAEKLSSILKRYDELTALLSSVEVVSDIKKLTELSKEQSSIEEISVASKEYLSVLEGIKENKELLEDKELSELAKEELKILEIQKSELETAIKQLLIPKDPNDDKNIYLELRAGTGGDEAGIFVGDLFKAYCRYADLKKWKVEIVSSSENSVGGYKEIIVLIKGKGVYSRLKFEAGTHRVQRVPETESQGRIHTSAITVAIMPEVDDVEVSINPSDLKIEVFRAGGHGGQCVNTTDSAVRITHLPTNISVSMQDEKSQHKNKDKALKILKARLYEKQIEEQQLANAKDRKEQVGSGDRSERIRTYNYPQNRLSEHRINLTLYSLEEIMLSGNLDEVINPLIAHAQSQFE
>NC_000921.1|WP_001273627.1|77725_77995_+|30S-ribosomal-protein-S20
MANHKSAEKRIRQTIKRTERNRFYKTKVKNIIKAVREAVAINDVAKAQERLKIANKELHKFVSKGILKKNTASRKVSRLNASVKKIALA
>NC_000921.1|WP_000688418.1|76298_77636_-|phosphoglucosamine-mutase
MKIFGTDGVRGKAGVKLTPMFVMRLGIAAGLYFKKHSQTNKILIGKDTRKSGYMVENALVSALTSIGYNVIQIGPMPTPAIAFLTEDMRCDAGIMISASHNPFEDNGIKFFNSYGYKLKEEEERAIEEIFHDEELLHSSYKVGESVGSAKRIDDVIGRYIAHLKHSFPKHLNLQKLRIVLDTANGAAYKVAPVVFSELGADVLVINDEPNGCNINEQCGALHPNQLSQEVKKYRADLGFAFDGDADRLVVVDNLGNIVHGDKLLGVLGVYQKSKNALSSQAVVATSMSNLALKEYLKSQDLELKHCAIGDKFVSECMRLNKANFGGEQSGHIIFSDYAKTGDGLVCALQVSALVLESKLVSSIALNPFELYPQSLVNLNIQKKPPLESLKGYSALLKELDQLEIRHLIRYSGTENKLRILLEAKDEKLLESKMQELKEFFEGQLC
>NC_000921.1|WP_000935478.1|75813_76305_-|lipoprotein-signal-peptidase
MLNTTQKSLLVFMGVFFLIFGVDQAIKHAILEGFHYESLVIDIVLVFNKGVAFSLLSFLEGGLKYLQILLILGLFIFLMRQKELFKSHAIEFGMVFGAGVSNVLDRFVHGGVVDYVYYHYGFDFAIFNFADVMIDVGVGVLLLRQFFFKQKQNKIKGIITLFK
>NC_000921.1|WP_000779233.1|74743_75460_-|urease-subunit-alpha
MKLTPKELDKLMLHYAGELARKRKEKGIKLNYVEAVALISAHIMEEARAGKKTAAELMQEGRTLLKPDDVMDGVASMIHEVGIEAMFPDGTKLVTVHTPIEANGKLVPGELFLKNEDITINEGKKAVSVKVKNVGDRPVQIGSHFHFFEVNRCLDFDREKTFGKRLDIASGTAVRFEPGEEKSVELIDIGGNRRIFGFNALVDRQADNESKKIALHRAKERGFHGAKSDDNYVKTIKE
>NC_000921.1|WP_000724295.1|73030_74740_-|urease-subunit-beta
MKKISRKEYVSMYGPTTGDKVRLGDTDLIAEVEHDYTIYGEELKFGGGKTLREGMSQSNNPSKEELDLIITNALIVDYTGIYKADIGIKDGKIAGIGKGGNKDMQDGVKNNLSVGPATEALAGEGLIVTAGGIDTHIHFISPQQIPTAFASGVTTMIGGGTGPADGTNATTITPGRRNLKWMLRAAEEYSMNLGFLAKGNASNDASLADQIEAGAIGFKIHEDWGTTPSAINHALDVADKYDVQVAIHTDTLNEAGCVEDTMAAIAGRTMHTFHTEGAGGGHAPDIIKVAGEHNILPASTNPTIPFTVNTEAEHMDMLMVCHHLDKSIKEDVQFADSRIRPQTIAAEDTLHDMGIFSITSSDSQAMGRVGEVITRTWQTADKNKKEFGRLKEEKGDNDNFRIKRYLSKYTINPAIAHGISEYVGSVEVGKVADLVLWSPAFFGVKPNMIIKGGFIALSQMGDANASIPTPQPVYYREMFAHHGKAKYDANITFVSQAAYDKGIKEELGLERQVLPVKNCRNITKKDMQFNDTTAHIEVNPETYHVFVDGKEVTSKPANKVSLAQLFSIF
>NC_000921.1|WP_000901274.1|72219_72807_-|acid-activated-urea-channel
MLGLVLLYVGIVLISNGICGLTKVDPKSTAVMNFFVGGLSIVCNVVVITYSALHPTAPVEGAEDIVQVSHHLTSFYGPATGLLFGFTYLYAAINHTFGLDWRPYSWYSLFVAINTVPAAILSHYSDMLDDHKVLGITEGDWWAIIWLAWGVLWLTAFIENILKIPLGKFTPWLAIIEGILTAWIPAWLLFIQHWV
>NC_000921.1|WP_000583091.1|71705_72218_-|urease-accessory-protein-UreE
MIIERLVGNLRDLNPLDFNVDHVDLEWFETRKKIARFKTRQGKDIAIRLKDAPKLGLSQGDILFKEEKEIIAVNILDSEVIHIQAKSVAEVAKICYEIGNRHAALYYGESQFEFKTPFEKPTLALLEKLGVQNRVLSSKLDSKERLTVSMPHSEPNFKVSLASDFKVVVK
>NC_000921.1|WP_000357456.1|70911_71682_-|urease-accessory-protein-UreF
MDKGKSVKSTKKSVGMPPKTPKTDNNANSHVDNEFLILQVNDAVFPIGSYTHSFGLETYIQQKKVTNKESALEYLKANLSSQFLYTEMLSLKLTYESTLQQDLKKILGIEEVIMLSTSPMELRLANQKLGNRFIKTLQAMNELDMGAFFNAYAQTTKDPTHATSYGVFAASLNMELKKALRHYLYAQTSNMVINCVKSVPLSQNDGQKILLSLQSPFNQLIEKTLELDESHLCAASVQNDIKAMQHESLYSRLYMS
>NC_000921.1|WP_000843375.1|82799_84821_-|methyl-accepting-chemotaxis-protein
MKSTRIGSKIVMMVCAVVIVISAVMGVIISYKVESVLQSQATELLQKKAQLVSFKIQGIMKRIFMGANTLERFLSDENGAINDTLKRRMLSEFLLANPHVLLVSAIYTNNNERMITAMNMDSKIAYPNTALNENMTNQIHSLKSITRSDPYYKEVNGDKIYGMDITLPLMGKNQNVIGALNFFLNIDAFYTDVVGKKKSNTFLMGKDGRILINPNREIQDKILSAINPDKRVAKAVEYYNQNEAGTLSYHSLSGNTETFLAIQPFDFFEEKGNNGNHWRWAIGKYVNKSLVFKEATNTKFIIITTLILGVLVLAFLVFIIISNLITKRISRVNNTLNDFFNLLNNPKNNHAISLTPPSAYDEIGQMQASINENILKTQESIQADNKAIQNSIEVTNYVENGDFTQEIACVPKNKDLQALRNTINSIIQYFRNQIGADIESLNNALEHYKNLDFTHHIQNPKANMEKALNTLGQEISSMLKASLGFANALNHESKDLKTCVDNLTKTAHKQERSLKNTTQSLEEITNIITMIDSKSQEMISQGEDIKSVVDMIRDIADQTNLLALNAAIEAARAGEHGRGFAVVADEVRKLAERTQKSLSEIEANINILVQSIADNAESIKMQNKGVENIHNSINALQQDVQDNLTIANHSLQVSTKIDGISQDILEDVSKKKF
>NC_000921.1|WP_001227269.1|84970_85360_-|30S-ribosomal-protein-S9
MRKIYATGKRKTAIAKVWLTPGKGELSINEQSLNQWLGGHEAIKMKVMQPLLLTKQEQSVDIKAVVFGGGYSAQAEALRHGISKALNAYDIAFRAILKPKGLLTRDSRVVERKKYGKRKARRSPQFSKR
>NC_000921.1|WP_000167675.1|85356_85782_-|50S-ribosomal-protein-L13
MTKTAKVNDIVRDWVVLDAKDKVFGRLITEIAVLLRGKHRPFYTPNVDCGDFVVVINANKVKFSGMKLEDKEYFTHSGYFGSTKSKTLQEMLEKTPEKLYHLAVRGMLPKTKLGKAMIKKLKVYRDDKHPHTAQTSKKDAK
>NC_000921.1|WP_001168427.1|86133_86322_-|DUF5408-family-protein
MQKEQEAQEIAKKAVKIVFFLGLVVVLLMMINLYMLINQINASAQMSHQIKKIEERLNQEQK
>NC_000921.1|WP_000061443.1|86328_87681_-|FAD-dependent-oxidoreductase
MSMEFDAVIIGGGVSGCATFYTLSEYSSLKRVAIVEKCSKLAQISSSAKANSQTIHDGSIETNYTPEKAKKVRLSAYKTRQYALNKGLQNEVIFETQKMAIGVGDEECEFMKKRYESFKEIFVGLEEFDKQKIKELEPNVILGANGIDRHENIIGHGYRKDWSTMNFAKLSENFVEEALKLKPNNQVFLNFKVKKIEKRNDTYAVISEDAEEVYAKFVLVNAGSYALPLAQSMGYGLDLGCLPVAGSFYFVPDLLRGKVYTVQNPKLPFAAVHGDPDAVIKGKTRIGPTALTMPKLERNKCWLKGISLELLKMDLNRDVFKIAFDLMSDKEIRNYVFKNMVFELPIIGKRKFLKDAQKIIPTLSLEDLEYAHGFGEVRPQVLDRTKRKLELGEKKICTHKGITFNMTPSPGATSCLQNALVDSQEIAAYLGESFELERFYKDLSPEELEN
>NC_000921.1|WP_001268623.1|87734_89108_-|hypothetical-protein
MRYFLVVFLFLFVGCMKKDFTLKDLSLPQEASSYLASSQNSSHNNQSIDPQALRENLKESYLKAWYSPWLDAKVKSNKKEVFWILKEMNKSTGYGEDLKPNAKAFNDELIKNMDIERYPSTKIKAVVVRNNDVRAVPTNKPYYLSPKGYPFDRFQNSLVFPGTPVLITPFNPDKTYPPLQSSFVYGWIKVSELAYMRDKEIELLTKLKNYDMPIKEKNPLYTDYGEFYPHAKIGELFPLIPQIQNASQIPPKKELKAYGFLKDAKGYAALQSVFLDEKDFFVFPKAFTSEIMAYFINTMLGQKYGWGGLLGNRDCSAFTRDSFANFGILLPRNSYAQSRYANNYVDLSSMKAKEKEDYIIKNATPFGTLIYLKGHIMLYLGERNHQAIVAHSIWSVQTQKHFKTLSHKIGGVVITSLWLAEEHNGAFSKKKLLIDRVLGMSDLKDFVHKTSSPLNAN
>NC_000921.1|WP_160442684.1|89127_91200_-|RNA-polymerase-sigma-factor-RpoD
MGSYFMECPMKKKANEEKAPKRAKQEAKTEATQENKAKESNKENKNNKAKEGKIKEAKTKESKVKETAKEPIPVKKLSFNEALEELFANSLSDCVSYESIIQISAKVPTLAQIKKIKELCQKYQKKLVSSSEYAKKLNAIDKIKNTEEKQKVLDEELEDGYDFLKEKDFLEWSRSDSPVRMYLREMGDIKLLSKDEEIELSKQIRLGEDIILDAICSVPYLIDFIYAYKDALINRERRVKELFRSFDDDDENSVSDPKKDDDSEEDEENEERKKVVSEKDKKRVEKVQESFKALDKAKKEWLKALEAPIDEKEDELVRSLTLAYKRQTLKDRLYDLEPTSKLINELVKTMETTLKSGDGFEKELKRLEYKLPLFNDTLIANHKKILANITNMTKEDIIAQVPEATMVSVYMDLKKLFLTKEASEEGFDLAPNKLKEILEQIKRGKLISDRAKNKMAKSNLRLVVSIAKRFTSRGLPFLDLIQEGNIGLMKAVDKFEHEKGFKFSTYATWWIKQAISRAIADQARTIRIPIHMIDTINRINKVMRKHIQETGKEPDLEVVAEEVGLSLDKVKNVIKVTKEPISLETPVGNDDDGKFGDFVEDKNIVSSIDHIMREDLKAQIESVLDQLNEREKAVIRMRFGLLDDESDRTLEEIGKELNVTRERVRQIESSAIKKLRSPQYGRILRNYLRI
>NC_000921.1|WP_000250152.1|91395_92091_-|aminodeoxyfutalosine-nucleosidase
MVQKIGILGAMREEITPILELFGVDFEEIPLGGNVFHKGVYHNKEIIVAYSKIGKVHSTLTTTSMILAFGVQKVLFSGVAGSLVKDLKINDLLVATQLVQHDVDLSAFDHPLGFIPESAIFIETSGSLNALAKKIANEQHIALKEGVIASGDQFVHSKERKEFLVSEFKASAVEMEGASVAFVCQKFGVPCCVLRSISDNADEKAGMSFDEFLEKSAHTSAKFLKSMVDEL
>NC_000921.1|WP_001199062.1|92101_93031_-|ACP-S-malonyltransferase
MQYALLFPGQGSQCIGMGKSFYESHTLAKELFERASNVLKVDMKKTLFEENELLKESAYTQPAIYLVSYIAYQLLNKQANGGLKPVFALGHSLGEVSAVSLSGALDFEKALKLTHQRGKMMQEACANKDASMMVVLGVSEESLLSLCQRTKNVWCANFNGGMQVVLAGVKDDLKALEPTLKEMGAKRVVFLEMSVASHCPFLEPMIFKFQELLEKSLKDKFHFEIISNATNEAYHNKSKAVELLSLQLTQPVRYQDCVKSNNDRVDVFFELGCGSVLKGLNKRLSNKPTISVGDNKGLDEAIEFLEEYV
>NC_000921.1|WP_001918721.1|93457_93676_+|hypothetical-protein
MKNHLPFDTFLKSLKTSNRTLDFFTDWQKCLKNKNEISIALNHLNFLLGKDTKELKNCIKPFLKNTPKLLMF

Crispr_ID: NC_000921_3

• CRISPR_ID: NC_000921_3
• CRISPR_location: 946471-946672
• CRISPR_type: Orphan
• Repeat_type: I-B
• Spacer_info: 3 spacers

Consensus repeat of NC_000921_3

Consensus_repeat	Method
TTCAATCAAGGCACTTATAATTTTAATAACA	PILER-CR

spacers of NC_000921_3

>3.1|946502|29|NC_000921|PILER-CR
GCGCCACTTTAAGCTTCAATAACAGCAAT
>3.2|946562|31|NC_000921|PILER-CR
CAGCGCCCAATCCACTTTTGAAAACAGCAAT
>3.3|946624|23|NC_000921|PILER-CR
ATACTAGCTTTAATAACGACACC

CRISPR arrays and Neighbor proteins around NC_000921_3

CRISPR arrays

The CRISPR arrays of NC_000921_3

>merge|NC_000921|3|946471-946672|PILER-CR
TTCAATCAAGGGACTTATAATTTTAGTAACAGCGCCACTTTAAGCTTCAATAACAGCAATTTCAATCAAGGGACTTATCACTTTAACAGCGCCCAATCCACTTTTGAAAACAGCAATTTCAATCAAGGCACTTATAATTTTAATGACAATACTAGCTTTAATAACGACACCTTCAATCAAGGCACTTATAATTTTAATAGCA

>NC_000921|3|1|946471-946672|PILER-CR
TTCAATCAAGGGACTTATAATTTTAGTAACA	GCGCCACTTTAAGCTTCAATAACAGCAAT
TTCAATCAAGGGACTTATCACTTTAACAGCG	CCCAATCCACTTTTGAAAACAGCAATTTCAA
TCAAGGCACTTATAATTTTAATGACAATACT	AGCTTTAATAACGACACCTTCAA
TCAAGGCACTTATAATTTTAATAGCA

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_000921.1|WP_000894602.1|928329_930360_+|ATP-dependent-helicase	unknown	unknown	gnl|CDD|223288
NC_000921.1|WP_000410405.1|957597_958140_+|GTP-cyclohydrolase-I-FolE	unknown	unknown	gnl|CDD|129173
NC_000921.1|WP_001115880.1|954112_954319_-|4-oxalocrotonate-tautomerase-family-protein	unknown	unknown	gnl|CDD|129125
NC_000921.1|WP_000998444.1|937357_939805_-|TonB-dependent-receptor	unknown	unknown	gnl|CDD|273808
NC_000921.1|WP_000236788.1|960524_961127_+|6-pyruvoyl-tetrahydropterin-synthase-family-protein	unknown	unknown	gnl|CDD|223792
NC_000921.1|WP_000688593.1|944611_945610_+|type-I-glyceraldehyde-3-phosphate-dehydrogenase	unknown	unknown	gnl|CDD|273675
NC_000921.1|WP_001034747.1|959863_960523_+|hypothetical-protein	unknown	unknown	unknown
NC_000921.1|WP_000592444.1|931523_933086_+|Hop-family-adhesin-AlpA	unknown	unknown	gnl|CDD|280099
NC_000921.1|WP_000722501.1|959063_959867_+|5'/3'-nucleotidase-SurE	unknown	unknown	gnl|CDD|223570
NC_000921.1|WP_001099637.1|954487_955069_+|recombination-protein-RecR	unknown	unknown	gnl|CDD|273176
NC_000921.1|WP_001240296.1|943773_944466_-|Bax-inhibitor-1/YccA-family-protein	unknown	unknown	gnl|CDD|198414
NC_000921.1|WP_001052441.1|955065_956211_+|tRNA-pseudouridine(13)-synthase-TruD	unknown	unknown	gnl|CDD|272903
NC_000921.1|WP_001126571.1|940416_943674_-|carbamoyl-phosphate-synthase-large-subunit	unknown	unknown	gnl|CDD|235393
NC_000921.1|WP_001160423.1|952942_954043_+|Hop-family-outer-membrane-protein-HopJ/HopK	unknown	unknown	gnl|CDD|280099
NC_000921.1|WP_160442690.1|956179_957130_+|zinc-metalloprotease-HtpX	unknown	unknown	gnl|CDD|235081
NC_000921.1|WP_000806979.1|935475_937020_-|outer-membrane-beta-barrel-protein-HofG	unknown	unknown	gnl|CDD|334957
NC_000921.1|WP_000070317.1|958155_959067_+|polyprenyl-synthetase-family-protein	unknown	unknown	gnl|CDD|223220
NC_000921.1|WP_000427189.1|927175_928321_+|class-I-SAM-dependent-methyltransferase	unknown	unknown	gnl|CDD|223897
NC_000921.1|WP_000812557.1|933107_934691_+|Hop-family-adhesin-AlpB	unknown	unknown	gnl|CDD|280099
NC_000921.1|WP_001229954.1|939980_940412_-|hypothetical-protein	unknown	unknown	gnl|CDD|376519

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_000921.1|WP_000894602.1|928329_930360_+|ATP-dependent-helicase	gnl|CDD|223288	COG0210, UvrD, Superfamily I DNA and RNA helicases [DNA replication, recombination, and repair].	3.53696e-134
NC_000921.1|WP_000410405.1|957597_958140_+|GTP-cyclohydrolase-I-FolE	gnl|CDD|129173	TIGR00063, GTP_cyclohydrolase_1, GTP cyclohydrolase I. alternate names: Punch (Drosophila),GTP cyclohydrolase I (EC 3.5.4.16) catalyzes the biosynthesis of formic acid and dihydroneopterin triphosphate from GTP. This reaction is the first step in the biosynthesis of tetrahydrofolate in prokaryotes, of tetrahydrobiopterin in vertebrates, and of pteridine-containing pigments in insects. [Biosynthesis of cofactors, prosthetic groups, and carriers, Folic acid].	2.71842e-106
NC_000921.1|WP_001115880.1|954112_954319_-|4-oxalocrotonate-tautomerase-family-protein	gnl|CDD|129125	TIGR00013, Probable_tautomerase_K2, 4-oxalocrotonate tautomerase family enzyme. 4-oxalocrotonate tautomerase is a homohexamer in which each monomer is very small, at about 62 amino acids. Pro-1 of the mature protein serves as a general base. The enzyme functions in meta-cleavage pathways of aromatic hydrocarbon catabolism. Because several Arg residues located near the active site in the crystal structure of Pseudomonas putida are not conserved among all members of this family, because the literature describes a general role in the isomerization of beta,gamma-unsaturated enones to their alpha,beta-isomers, and because of the presence of fairly distantly related paralogs in Campylobacter jejuni, the family is regarded as not necessarily uniform in function. [Energy metabolism, Other].	2.46126e-26
NC_000921.1|WP_000998444.1|937357_939805_-|TonB-dependent-receptor	gnl|CDD|273808	TIGR01786, hemoglobin-haptoglobin-binding_protein, TonB-dependent hemoglobin/transferrin/lactoferrin receptor family protein. This model represents a family of TonB-dependent outer membrane receptor/transporters acting on iron-containing proteins such as hemoglobin, transferrin and lactoferrin. Two subfamily models with a narrower scope are contained within this model, the heme/hemoglobin receptor family protein model (TIGR01785) and the transferrin/lactoferrin receptor family model (TIGR01776). Accessions which score above trusted to this model while not scoring above trusted to the more specific models are most likely to be hemoglobin transporters. Nearly all of the species containing trusted hits to this model have access to hemoglobin, transferrin or lactoferrin or related proteins in their biological niche. [Transport and binding proteins, Cations and iron carrying compounds, Transport and binding proteins, Porins].	4.22774e-44
NC_000921.1|WP_000688593.1|944611_945610_+|type-I-glyceraldehyde-3-phosphate-dehydrogenase	gnl|CDD|273675	TIGR01534, Glyceraldehyde-3-phosphate_dehydrogenase, glyceraldehyde-3-phosphate dehydrogenase, type I. This model represents glyceraldehyde-3-phosphate dehydrogenase (GAPDH), the enzyme responsible for the interconversion of 1,3-diphosphoglycerate and glyceraldehyde-3-phosphate, a central step in glycolysis and gluconeogenesis. Forms exist which utilize NAD (EC 1.2.1.12), NADP (EC 1.2.1.13) or either (1.2.1.59). In some species, NAD- and NADP- utilizing forms exist, generally being responsible for reactions in the anabolic and catabolic directions respectively. Two Pfam models cover the two functional domains of this protein; pfam00044 represents the N-terminal NAD(P)-binding domain and pfam02800 represents the C-terminal catalytic domain. An additional form of gap gene is found in gamma proteobacteria and is responsible for the conversion of erythrose-4-phosphate (E4P) to 4-phospho-erythronate in the biosynthesis of pyridoxine. This pathway of pyridoxine biosynthesis appears to be limited, however, to a relatively small number of bacterial species although it is prevalent among the gamma-proteobacteria. This enzyme is described by TIGR001532. These sequences generally score between trusted and noise to this GAPDH model due to the close evolutionary relationship. There exists the possiblity that some forms of GAPDH may be bifunctional and act on E4P in species which make pyridoxine and via hydroxythreonine and lack a separate E4PDH enzyme (for instance, the GAPDH from Bacillus stearothermophilus has been shown to posess a limited E4PD activity as well as a robust GAPDH activity). There are a great number of sequences in the databases which score between trusted and noise to this model, nearly all of them due to fragmentary sequences. It seems that study of this gene has been carried out in many species utilizing PCR probes which exclude the extreme ends of the consenses used to define this model. The noise level is set relative not to E4PD, but the next closest outliers, the class II GAPDH's (found in archaea, TIGR01546) and aspartate semialdehyde dehydrogenase (ASADH, TIGR01296) both of which have highest-scoring hits around -225 to the prior model. [Energy metabolism, Glycolysis/gluconeogenesis].	3.41936e-158
NC_000921.1|WP_000236788.1|960524_961127_+|6-pyruvoyl-tetrahydropterin-synthase-family-protein	gnl|CDD|223792	COG0720, COG0720, 6-pyruvoyl-tetrahydropterin synthase [Coenzyme metabolism].	1.68474e-20
NC_000921.1|WP_000592444.1|931523_933086_+|Hop-family-adhesin-AlpA	gnl|CDD|280099	pfam01856, HP_OMP, Helicobacter outer membrane protein. This family seems confined to Helicobacter. It is predicted to be an outer membrane protein based on its pattern of alternating hydrophobic amino acids similar to porins.	8.21921e-55
NC_000921.1|WP_000722501.1|959063_959867_+|5'/3'-nucleotidase-SurE	gnl|CDD|223570	COG0496, SurE, Predicted acid phosphatase [General function prediction only].	4.00622e-125
NC_000921.1|WP_001099637.1|954487_955069_+|recombination-protein-RecR	gnl|CDD|273176	TIGR00615, Recombination_protein_RecR, recombination protein RecR. All proteins in this family for which functions are known are involved in the initiation of recombination and recombinational repair. RecF is also required. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair].	4.59827e-95
NC_000921.1|WP_001240296.1|943773_944466_-|Bax-inhibitor-1/YccA-family-protein	gnl|CDD|198414	cd10432, BI-1-like_bacterial, Bacterial BAX inhibitor (BI)-1/YccA-like proteins. This family is comprised of bacterial relatives of the mammalian members of the BAX inhibitor (BI)-1 like family of small transmembrane proteins, which have been shown to have an antiapoptotic effect either by stimulating the antiapoptotic function of Bcl-2, a well-characterized oncogene, or by inhibiting the proapoptotic effect of Bax, another member of the Bcl-2 family. In plants, BI-1 like proteins play a role in pathogen resistance. A characterized prokaryotic member, Escherichia coli YccA, has been shown to interact with ATP-dependent protease FtsH, which degrades abnormal membrane proteins as part of a quality control mechanism to keep the integrity of biological membranes.	9.43326e-53
NC_000921.1|WP_001052441.1|955065_956211_+|tRNA-pseudouridine(13)-synthase-TruD	gnl|CDD|272903	TIGR00094, tRNA_pseudouridine_synthase_D, tRNA pseudouridine synthase, TruD family. an EGAD loading error caused one member to be called surE, but that's an adjacent gene. MJ11364 is a strong partial match from 50 to 230 aa. [Protein synthesis, tRNA and rRNA base modification].	1.6213e-137
NC_000921.1|WP_001126571.1|940416_943674_-|carbamoyl-phosphate-synthase-large-subunit	gnl|CDD|235393	PRK05294, carB, carbamoyl-phosphate synthase large subunit.	0
NC_000921.1|WP_001160423.1|952942_954043_+|Hop-family-outer-membrane-protein-HopJ/HopK	gnl|CDD|280099	pfam01856, HP_OMP, Helicobacter outer membrane protein. This family seems confined to Helicobacter. It is predicted to be an outer membrane protein based on its pattern of alternating hydrophobic amino acids similar to porins.	7.47989e-48
NC_000921.1|WP_160442690.1|956179_957130_+|zinc-metalloprotease-HtpX	gnl|CDD|235081	PRK02870, PRK02870, heat shock protein HtpX; Provisional.	0
NC_000921.1|WP_000806979.1|935475_937020_-|outer-membrane-beta-barrel-protein-HofG	gnl|CDD|334957	pfam02521, HP_OMP_2, Putative outer membrane protein. This family consists of putative outer membrane proteins from Helicobacter pylori (campylobacter pylori).	1.72546e-178
NC_000921.1|WP_000070317.1|958155_959067_+|polyprenyl-synthetase-family-protein	gnl|CDD|223220	COG0142, IspA, Geranylgeranyl pyrophosphate synthase [Coenzyme metabolism].	2.61898e-75
NC_000921.1|WP_000427189.1|927175_928321_+|class-I-SAM-dependent-methyltransferase	gnl|CDD|223897	COG0827, COG0827, Adenine-specific DNA methylase [DNA replication, recombination, and repair].	2.69274e-52
NC_000921.1|WP_000812557.1|933107_934691_+|Hop-family-adhesin-AlpB	gnl|CDD|280099	pfam01856, HP_OMP, Helicobacter outer membrane protein. This family seems confined to Helicobacter. It is predicted to be an outer membrane protein based on its pattern of alternating hydrophobic amino acids similar to porins.	1.01727e-53
NC_000921.1|WP_001229954.1|939980_940412_-|hypothetical-protein	gnl|CDD|376519	pfam01300, Sua5_yciO_yrdC, Telomere recombination. This domain has been shown to bind preferentially to dsRNA. The domain is found in SUA5 as well as HypF and YrdC. It has also been shown to be required for telomere recombniation in yeast.	0.000527858

Protein sequences

>NC_000921.1|WP_000688593.1|944611_945610_+|type-I-glyceraldehyde-3-phosphate-dehydrogenase
MKIFINGFGRIGRCVLRAILERNDTNPQLEVIGINDPANWEILAYLLEHDSTHGLLNKEVRYSNGKLIIGSLEIPVFNSIKDLKGVGVIIECSGKFLEPKTLENYLLLGAKKVLLSAPFMGEYDEKQYPTLVYGVNHFLYQNQAIVSNASCTTNAIAPICAILDKAFSIKEGMLTTIHSYTSDQKLIDLAHPLDKRRSRAAASNIIPTTTKAALALHKVLPNLKNKMHGHSVRVPSLDVSMIDLSLFLEKKALKDPINDLLITASKGTLKGVLEIDLKERVSSDFISNPNSVIIAPDLTFTLENMVKIMGWYDNEWGYSNRLVDMAQFMYHY
>NC_000921.1|WP_001240296.1|943773_944466_-|Bax-inhibitor-1/YccA-family-protein
MALYDRANSRNAYAEDSVLHESELVSFVKTTYKFFAGSLLLATVGALLGLMNFQAVVQYKWVFFIAEIVAFFGLMFSKSKPGLNLFMLFAFTSLSGVTLVPLLGMVIAKAGLGAVWQALGMTTIVFGLMSVYALKTKNDLANMGKMLFIALIVVVVCSLINLFLGSPMFQVVIAGASAILFSLYIAYDTQNIVKGMYDSPIDAAVSLYLDFLNVFISILQIIGIFSDRDK
>NC_000921.1|WP_001126571.1|940416_943674_-|carbamoyl-phosphate-synthase-large-subunit
MPKRTDISNILLIGSGPIVIGQACEFDYSGTQSCKTLKSLGYRVILINSNPATVMTDPEFSHQTYIQPITPENIAAIIKKEKIDAILPTMGGQTALNAVMQMHQRGMLEGVELLGAKIEAIKKGEDRQAFKEAMLKIGMDLPKGRYAYSELEALEAISEIGFPAIIRASFTLAGGGSGVAYNIEEFQELAKNALDASPINEILIEESLLGWKEYEMEVIRDGKDNCIIVCCIENIDPMGVHTGDSITIAPSLTLTDKEYQRMRDASFAILREIGVDTGGSNVQFAIHPETLRMVVIEMNPRVSRSSALASKATGFPIAKVATMLAVGFSLDEIKNDITNTPASFEPSLDYIVVKIPRFAFEKFAGVSSTLGTSMKSIGEVMAIGGNFLEALQKALCSLENNWLGFESLSKDLEAIKKEIRRPNPKRLLYIADAFRLGVSVDEVFELCQIDRWFLSQIQKLVKAEEGINSSVLTDAKKLRGLKNLGFSDARIATKIKENENLEVSPFEVELARSNLQIAPHFEEVDTCAAEFLSLTPYLYSTYAPNPLPPIGNKQEKQEKKILIIGSGPNRIGQGIEFDYCCVHASFALKDLNIKSVMLNCNPETVSTDYDTSDTLYFEPIHFECVKSIIQRERVDGIIVHFGGQTPLKLAKDLAKMQAPIIGTPFKVIDIAEDREKFSLFLKELDIKQPENGMAKSVDEAYSIANAIGFPIIVRPSYVLGGQHMQILENIEELRHYLESVTHSLEISPKNPLLIDKFLEKAVELDVDAICDKKEVYIAGILQHIEEAGIHSGDSACFIPSTLSPEILDEIERVSAKIALHLGVVGLLNIQFAVYQNSLYLIEVNPRASRTVPFLSKALGVPLAKVATRVMVLEDLKEALKFYDKKNIVEYSKGVYKPKMPHFVALKEAVFPFNKLYGSDLILGPEMKSTGEVMGIARSLGLAFFKAQTACFNPIKNKGLIFVSIKDKDKEEACVLMKRLVELGFELCTTEGTHKALEKAGVKSLKVLKISEGRPNIMDLMMNGEISMAINTSDHKSQDDAKLIRASVLKNHVSYFTTLSAIEVLLLALEESSQEDELLALQDYLK
>NC_000921.1|WP_001229954.1|939980_940412_-|hypothetical-protein
MALVYLAQSDTTIGLLSKDSEKLNALKGRPKNQSVLIESTDFTTLKSLVRAPNAFKNLVRRSAKTTFIYPNSKAVRVVKGRHGDFLKRFKTLYSTSANLTQCAYDKEIASNLADVIVSDERGLFESGSSKIFKLYKHKKVRVR
>NC_000921.1|WP_000998444.1|937357_939805_-|TonB-dependent-receptor
MNDKRFRKYCSFSIFLSLLGTFELEAKEEEKEEKKTERNKDKEKNAQHTLGKVTTQAAKIFNYNNQTTISSKELERRQANQISDMFRRNPNINVGGGAVIAQKIYVRGIEDRLARVTVDGVAQMGASYGHQGNTIIDPGMLKSVVVTKGAAQASAGPMALIGAIKMETRSASDFIPKGKDYAISGAATFLTNFGDRETIMGAYRNHHFDALLYYTHQNIFYYRDGDNAMKNLFDPKADNKVTASPSEQNNVMAKINGYLSERDTLTLSYNMTRDNANRPLRANFTGTFLPYSCGDFNAFPNEKNPSDCLFENDASLFKTYSVNLVHNVSLNYEREGGSRFGDPKLKINGYTSIRNVQIDPLFRPSDIATTIPFTPNPQLSQGEENQCVAQGGIYDALKQTCSITFKSLGGGSVVANKNLFIINSGFNANVIHTIDHKNDNLLEYGLNYQNLTTFDKAIPDSELVKPGDAPDACLRVTGPDDPNMNGRCQRNGATANVVGVYAQANYTLHPMVTLGAGTRYDVYTLVDKDWQLHVTQGFSPSAALNVSPLENLNFRLSYAYVTRGPMPGGLVWMRQDNLRYNRNLKPEIGQNAEFNTEYSSQYFDFRAAGFVQLISNYINQFSSTLFVTNLPAQDIIYVPGYEVSGTAKYKGFSLGLSVARSWPSLKGRLIADVYELAATTGNVFILTASYTIPRTGLSITWLSRFVTNLSYCSYSPYRNGPTDIDRRPSNCPKTPGIFHVHKPGYGVSSFFITYKPTYKKLKGLSLNAVFNNVFNQQYIDQASPVMSPDEPNQDKYARGMAEPGFNARFEISYKF
>NC_000921.1|WP_000806979.1|935475_937020_-|outer-membrane-beta-barrel-protein-HofG
MKQEKYFLTSSLSLLSFLLCPVEAFDYRFSGRVENFSKIGFNNSQINTKKGIYPTESFIDIVTLAQVKVNLLPKGTENHRLSVSLGGAIAAIPYDKTKYYINQANGKVFGSIVENFIGGYHGYFFNKYLGPAYAGTSQSASYHARPYVVDTAFLRYDYKDVFGFKAGRYEANIDFMSGSNQGWEVYYQPYKTETQRLRFWWWSSFGRGLAFNSWIYEFFATVPYLKKGGNPSNSNDFINYGWHGITTTYSYKGLDAQFFYYFAPKTYNAPGFKLVYDTNRNFENVGFRSQSMIMTTFPLYYRGWYNPETNTYSLEDSTPHGSLLGRNGVTLNIRQVFWWDNFNWSIGFYNTFGNSDAFLGSHTMPRGNNTSYISNEISVTTRHAGMIGYDFWDNTAYDGLADAITNANTFTFYTSVGGIHKRFAWHVFGRVSHANKNALGQVGRANEYSLQFNASYAFTESVLLNFRITYYGARINKGYQAGYFGAPKFNNPDGDFSANYQDRSYMMTNLTLKF
>NC_000921.1|WP_000812557.1|933107_934691_+|Hop-family-adhesin-AlpB
MKQNLKPFKMIKENLMTQSQKVRFLAPLSLALSLSFNPVGAEEDGGFMTFGYELGQVVQQVKNPGKIKAEELAGLLNSTTTNNTNINIAGTGGNVAGTLGNLFMNQLGNLIDLYPTLKTNNLHQCGSTNSGNGATAAAATNNSPCFQGNLALYNEMVDSIKTLSQNISKNIFQGDNNTTSANLSNQLSELNTASVYLTYMNSFLNANNQAGGIFQNNTNQAYENGVTAQQIAYVLKQASITMGPSGDSGAAGAFLDAALAQHVFNSANAGNDLSAKEFTSLVQNIVNNSQNALTLANNANISNSTGYQVSYGGNIDQARSTQLLNNTTNTLAKVTALNNELKANPWLGNFAAGNSSQVNAFNGFITKIGYKQFFGENKNVGLRYYGFFSYNGAGVGNGPTYNQVNLLTYGVGTDVLYNVFSRSFGSRSLNAGFFGGIQLAGDTYISTLRNSPQLASRPTATKFQFLFDVGLRMNFGILKKDLKSHNQHSIEIGVQIPTIYNTYYKAGGAEVKYFRPYSVYWVYGYAF
>NC_000921.1|WP_000592444.1|931523_933086_+|Hop-family-adhesin-AlpA
MIKKNRTLFLSLALCASISYAEDDGGFFTVGYQLGQVMQDVQNPGGAKSDELARELNADVTNNILNNNTGGNVAGALSNAFSQYLYSLLGAYPTKLNGNDVSANALLSGAVGSGTCAAAGTAGGTTLNTQSACTAAGYYWLPSLTDRILSTIGSQTNYGTNTNFPNMQQQLTYLNAGNVFFNAMNKALEKNGTATANSTSSTSGATGSDGQTYSQQAIQYLQGQQNILNNAANLLKQDELLLEAFNSAVAANIGNKEFNSAAFTGLVQGIIDQSQLVYNELTKNTISGSAVNNAGINSNQANAVQGRASQLPNALYNVQVTLDKINALNNQVRSMPYLPQFRAGNSRATNILNGFYTKVGYKQFFGKKRNIGLRYYGFFSYNGASVGFRSTQNNVGLYTYGVGTDVLYNIFSRSYQNRSVDMGFFSGIQLAGETFQSTLRDDPNVKLHGKINNTHFQFLFDFGMRMNFGKLDGKSNRHNQHTVEFGVVVPTIYNTYYKSAGTTVKYFRPYSVYWSYGYSF
>NC_000921.1|WP_000894602.1|928329_930360_+|ATP-dependent-helicase
MLETLQLNPEQLKAASALQGHNLIIASAGTGKTSTIVGRILHLLNNGIKPEEILLLTFTNKASNEMIARVAKYSKLSSKIEAGTFHAVAYRYLKEHYPNLSLKQPKELRKLLESIVDTKNALTDEDKKPYTSQHLYALYSLYTNALKQEDFSAWLSSKNPEHAPYAAFYENILEEFENTKKKHDYIDYNDLLLLFKKAMLERSSPYKEVLCDEFQDTNPLQESILDAINPPSLFCVGDYDQSIYAFNGADISIISNFTQKYKNARVFTLTKNYRSSKEILDLANQVIQHNQRIYPKNLEVVKSGKFNKPTLLNYNDNIAQCQDIAKRIVMRKNFKEVAVIFRNNASADQLEAALRSHNVPSKRKGSASFFESKEVALALDICALLFNPKDIMAAIHILSYISDIGSNTAKDIHEALMLLGNGDLKSALIQPNQEAKIYTKKKEITSMGLFEEIFALENSSRFNSVIDKAFHSHPVLMHPKISLNGAKMLSDFFILYTKAPIHSPSALIKHILESAFFQTFKTRLLKERSKNKDGSYNEFKKLQAQKRFNEKMDLLSSLAKNYQNLGRFLNGTLIGSSEATQGEGVNLLSVHASKGLEFKDVYIIDLMEGRFPNHKLMNTGGGIEEERRLFYVAITRAKENLWLSYAKNELRENAKPKEHKPSVFLYEAGLLKLDSK
>NC_000921.1|WP_000427189.1|927175_928321_+|class-I-SAM-dependent-methyltransferase
MENFLYQLEIKTLGQVFTPKNIVDFMLILKHNHGSVLEPSAGDGSFLKRLKKAVGIEIDPKICPKNALCMDFFDYPLENQFNTIIGNPPYVKHKDIAPSTKEKLHYSLFDERSNLYLFFIEKAIKHLKPKGELIFITPRDFLKSTSSVKLNEWIYKEGTITHFFELGDQKIFPNAMPNCVIFRFCKGDFSRITNDGLQFVCKKGILYFLNQSYTQKLSEVFKVKVGAVSGCDKIFKNETYGNLEFVTSITKRTNVLEKMVFVNKPNDYLLQHKDSLMQRKIKKFNENNWFEWGRMHHISPKKRIYVNAKTHQKNPFFIHQCPNYDGSILALFPYNQNLDLQNLCDKLNAINWQELGFVCDGRFLFSQRSLENALLPKDFLN
>NC_000921.1|WP_001160423.1|952942_954043_+|Hop-family-outer-membrane-protein-HopJ/HopK
MQFQKTLLSLSLLFLSYCIAEENGAYASVGFEYSISHAVEHNNPFLNQERIQTISNAQNKIYKLNQVKNEITNMPNTFNYINNALKNNAKLTPTEKQAETYYLQSTLQNIEKIVMLSGGVASNPKLVQALEKMQEPITNPLELVENLKNLELQFSQSQNSMLSSLSSQIAQISNSLNALDPSSYSKNVSSMYGVGLSVGYKHFFTKKKNQGFRYYLFYDYGYTNFGFVGNGFDGLGKMNNHLYGLGIDYLFNFIDNAQKHSSVGFYVGFALAGSSWVGSGLGMWVSQMDFINNYLTDYRAKMHTSFFQIPLNFGVRVNVDRHNGFEMGLKIPLAVNSFYETHGKGLNASLFFKRLVMFNVSYVYSF
>NC_000921.1|WP_001115880.1|954112_954319_-|4-oxalocrotonate-tautomerase-family-protein
MPFINIKLVPENGGPTNEQKQQLIEGVSDLMVKVLNKNKASIVVIIDEVDSNNYGLGGESIHHLRQKN
>NC_000921.1|WP_001099637.1|954487_955069_+|recombination-protein-RecR
MNTYKNSLNHFLNLVDCLEKIPNVGKKSAFKMAYHLGLENPYLALKITHALRNALENLKTCASCNALSETEVSEICSDESRQNSQLCMVLHPRDVFILEDLKDFLGRYYVLNSIEDVDFNALEKRLIGENIKEIIFAFPPTLANDSLMLYIEDKLQHLHLTFTKIAQGVPTGVNFENIDSVSLSRAFNSRIKA
>NC_000921.1|WP_001052441.1|955065_956211_+|tRNA-pseudouridine(13)-synthase-TruD
MNLNFMPLLHAYNHVSIDFHFNSSARDFCVHEVPLYEFSNTGEHAVIQVRKSGLSTLEMLQIFSQILGVKIAELGYAGLKDKNALTTQFISLPKKYAPLLEKNTSNFQERNLKILSLNYHHNKIKLGHLKGNRFFMRFKKMTPLNAQKTEQVLEQIAQFGMPNYFGSQRFGKFNDNHKEGLKILQNETKFAHQKLNAFLISSYQSYLFNSLLSKRLEISKIISAFSVKESLEFFKQKNLSVHSNALKALKNQAHPFKILEGDVMRHYPYGKFFDALELEKESERFLNKEAVPTGLLDGKKALYAKNLSLEIEKGFQHNLLSGHAKTLGSRRFFWVFVENITSQYIKEKAQFELEFYLPKGSYASALLKEIKHEKGENNDEF
>NC_000921.1|WP_160442690.1|956179_957130_+|zinc-metalloprotease-HtpX
MRKEKIMTNFEKIIAQNRLKTNAVLTTYCAIFAFIGLLVDAIRINANDLGIALFKLMTFQIFPTITIVMFVVAFVIILVCIQNFSSIMLSGDEYKLIDPSKVLSSKENQIHRLLLELLEEAKLHFEPKLYIINAPYMNAFASGWDESNSLIALTSALIERLDRDELKAVIAHELSHIRHNDIRLTMCVGILSNIMLLVANFSVYFFMGNRKNSGANLARMILWVLQIILPFLTLLLQMYLSRTREYMADSGAAFLMHDNKPMIRALQKISNDYTNNDYKEIDKNSTRSAAYLFNAEMFSTHPSIKNRIQSLRKRVI
>NC_000921.1|WP_000410405.1|957597_958140_+|GTP-cyclohydrolase-I-FolE
MEKFFNQFFENIGEDKNREGLKETPKRVQELWKFLYKGYKEDPRVALKSAYFQGVCDEMIVAQNIEFYSTCEHHLLPFFGNISVGYIPKEKIVGISAIAKLIEIYSKRLQIQERLTTQIAETFDEIIEPRGVIVVCEAKHLCMSMQGVQKQNAIIKTSVLRGLFKKDPKTRAEFMQLLKS
>NC_000921.1|WP_000070317.1|958155_959067_+|polyprenyl-synthetase-family-protein
MSNPNLSFYCNECERFESFLKNHYLHLEGFHPYLEKAFFEMVLNGGKRFRPKLFLAVLCSLVGKKDYSNQQTEYFKIALSIECLHTYSLIHDDLPCMDNAILRRNHPTLHAKYDETTAVLIGDALNTYSFELLSNSLLESRIIVELVKILSANGGIKGMILGQALDCYFENTPLNLEQLTFLHEHKTAKLISASLIMGLVASGINDEELLKWLQAFGLKMGLCFQVLDDIIDVTQDEKESGKTTHLDSAKNSFVNLLGLKKASGYAQTLKTEILNDLNALEPTYLSLQENLNALLNTLFKGKT
>NC_000921.1|WP_000722501.1|959063_959867_+|5'/3'-nucleotidase-SurE
MKKILLTNDDGYHAKGIKALEQALENMAEIYVVAPKHEKSACSQCITITAPLRAEKIKGKEGRHYRIDDGTPSDCVYLAINELFKHVCFDLVISGINLGSNMGEDTIYSGTVAGAIEGTIQGVPSIAISQILSNKNKNTPLSFDLAQKIIQDLVQNVFTKGYPLKGRKLLNVNVPNCSLQEYKGERITPKGYRLYKKEVHKRTDPKNESYFWLGLHPLKWQKRENEDRLSDFDAIASNHASITPLNLDLTSYDDLKSLESWHEGMLK
>NC_000921.1|WP_001034747.1|959863_960523_+|hypothetical-protein
MNKKHRLAFLGLIVGVLFFFSACQHRLHMGYYSEVTGDYLFNYNSTIVVAYDRSDAMTSYYINVIVYELQKLGFYNVFTQAEFPLDKAKNVIYVRIVRNISAVPFYQYNYQLIDQVNKPCYFLGGQFYCSQTPTDYYAINGFSEQILMSANSHFILDWYDVVLQKRVLYVDGSVSGRTCGYQMLYRDLIKSTIKRIDFNRPERYYYNLRLPLYQPCYRQ
>NC_000921.1|WP_000236788.1|960524_961127_+|6-pyruvoyl-tetrahydropterin-synthase-family-protein
MVIRRLYKFCASHVVRNCSSLKCAQNIHGHNYEVEVFIETNRLDNANMALDFGLMQQEMQTFIDSFDHAHHFWDKESPEFQRFIENHCVRYVKCSFNLSAESYALMFLYYLTKILQKSVFSNNEGELKVSSVRVHETKNGYAESFLKDLENPHFKSLVHDHCVSFSQGIQSLWHDKDFFHKIISDEKQCFFHAKPLHQIP

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NC_000921_3	3.2|946562|31|NC_000921|PILER-CR	946562-946592	31	MK448589	Streptococcus satellite phage Javan632, complete genome	4592-4622	6	0.806
NC_000921_3	3.2|946562|31|NC_000921|PILER-CR	946562-946592	31	NZ_CP022523	Pseudoalteromonas sp. NC201 plasmid pNC201, complete sequence	752261-752291	7	0.774
NC_000921_3	3.2|946562|31|NC_000921|PILER-CR	946562-946592	31	U88974	Streptococcus thermophilus temperate bacteriophage O1205, complete genome	23169-23199	8	0.742
NC_000921_3	3.2|946562|31|NC_000921|PILER-CR	946562-946592	31	NC_004303	Streptococcus phage O1205, complete genome	23169-23199	8	0.742

1. spacer 3.2|946562|31|NC_000921|PILER-CR matches to MK448589 (Streptococcus satellite phage Javan632, complete genome) position: , mismatch: 6, identity: 0.806

cagcgc-ccaatccacttttgaaaacagcaat	CRISPR spacer
-accgtaccaatcgccttttgaaaacagcaag	Protospacer
 * **. ******  **************** 

2. spacer 3.2|946562|31|NC_000921|PILER-CR matches to NZ_CP022523 (Pseudoalteromonas sp. NC201 plasmid pNC201, complete sequence) position: , mismatch: 7, identity: 0.774

--cagcgcccaatccacttttgaaaacagcaat	CRISPR spacer
atcaagg--caatctccttttgaaaacagcaac	Protospacer
  **. *  *****. ****************.

3. spacer 3.2|946562|31|NC_000921|PILER-CR matches to U88974 (Streptococcus thermophilus temperate bacteriophage O1205, complete genome) position: , mismatch: 8, identity: 0.742

cagcgcccaatccacttttgaaaacagcaat	CRISPR spacer
tagcgcccaaaacacttttgaaaactgatcc	Protospacer
.*********  ************* *   .

4. spacer 3.2|946562|31|NC_000921|PILER-CR matches to NC_004303 (Streptococcus phage O1205, complete genome) position: , mismatch: 8, identity: 0.742

cagcgcccaatccacttttgaaaacagcaat	CRISPR spacer
tagcgcccaaaacacttttgaaaactgatcc	Protospacer
.*********  ************* *   .

Prophage detection

Region	Region Position	Protein_number	Hit_taxonomy	Key_proteins	Att_site
DBSCAN-SWA_1	1492475 : 1503407	9	uncultured_virus(16.67%)	NA	NA

Sequences of DBSCAN-SWA_1

Nucleotide sequences of DBSCAN-SWA_1

>NC_000921|1492475:1503407|DBSCAN-SWA
ACTAACCTTTTAATTCATTCCAACGCTTAGCGATAAACGCGCTTGTTTCTAACGGCACCCTCAAAGGATAGACTTCATCATTAAGAATGCGTTGGATTTCTTGCTGCAACTCTGGGGCGTTTTTTTCTTCAATTTCAAAAATCAATTCGTCATGCACTTGCAAAAGCAGCCTCACCGAAGGGTTGTTTTTGAAACGCTCGCTCACTTTAAGCATGCCTAATTTCAATAAATCGCTGGCACTCCCTTGAAAAATCGCATTCACGCCCTCTCGCAAATAATTGCCCTTGACATAATCATTCACGCCGGTAAAATCAAACACCCGGTAACGCCCCAGCAAAGTAAAAGCTTTAGAAGTTTTTAAAATCTCTTCTCGCATGCCATTCAAATAATCTTTAATGCTAGGGAATCGCTTGAAATACGCTTCTATGTAACTTTTAGCCTCACTTAAAGGGATGCTTAAAGTTTCGCTCAATTTCTTACTCCCCATGCCATACACCAGCCCAAAATTAATGCTTTTAGCGATGGATCGTTTTTCTTTGGCTAAATCTTCTCCAAACAACGCCTTAGAAGTTTCTAAATGGATGTCTCGCCCCTTTAAAAACGCTTCCATTAAATCCTTATCCTGGCTGAAATGGGCCAACAAGCGTAATTCAATCTGCGAATAATCCACCCCTAATAAACAATATTCTTTAGAGCTAGCGATAAAACCCTTACGAATGAGTAAGCCTTTAGGCGATCGCACCGGGATATTTTGCAAATTAGGCGAATGCGAGCTTAAACGCCCGGTAGCTGTGCCGGTTTGGATGAAAGTGGTATGGATTTTATCGTCTTTGTCTTTTAAGCGCAATAAGGGGGTCGTGTAAGTGTTAAAAAGCTTATTCAATTCCCTGTATTCTAAAATCAAAGGGATGCTTGGGTGCTTGTCTAGGATTTTTAACAAGTTTTTTTCATCGGTAGAGTGGCTTTTATTTTTAGGAAGCCCTAATTTATCATACAAGACTTCGCCAAGTTGCTTGGGCGAATTGAGGTTGAAATCCACGCCGATTAGATCCAAAATTTGGCGCTCTAAAACGTTTAATTCATTCTTAAACTCCTGCTCTAAGCGCTTGAAATAAGGCGCATCAATCTTAAAGCCTTGAAATTCCATGCCCATTAAAACTTTCACAAACGGCGTTTCAATGTCTCTAGCTAAAGTGAGCAAATCCTCTTCTAGCCCCCCTTTTTCAAAGTATTCGCACAAACGCTTTAAGGCGTTTAATTCCATGCTTAAAAGTTCTGATTTTTCCGCCTTACTTTTTGTCTTAAAATCTTTGATCTTTTCATGCGGGATTAAATCTTCTTTTAAATATTCCTTTAAAACCTCATCAAACCCCACTTTTTCCGGATTCTTTAAAAACGCTAAAATCTGAGTGTCTTGGATGCGGATATTTTCCAAAGGCACCTGATATTTGGCTTTTAAAAAGCTTAATAAAGGCTTTAAATCATGCCCAATGATACACGCATGCTGTAACATTTGAGAAAAAGCGTTTTGTAAAAATTCCAAAGAAAAGGGCGAAAACAACGCCTCTTCTAAAGGTAAAAAATAGCCTTGATCTTGTAATAAAAACGCTAGGGCTAGAATTTTTTTGTCTTTATCCAAAACCAAACGCATAAAAACCCTAGCGTTAGGGTTTTCTAATTTTTCTAAAAACATGCTCAAAGGCTCAGCGCTTTCTAAAACAATCATGCGCGATTTTTTAGGGGCGTTGTCTAAGGCGGGGGTATTGTCTAATATAGGCGTGCTGTTTAATATGGGCACGTTTTCTACAATGAAAGGGGAATTTTCTAAATCCCTTAAGGTAGAAATGAAACCATATTCTTTCAATTCATCTTTGATTTTCAACAAGGGGTTTTCGCTCGGAAAAGCGCAACTTAAAAAATCAAATTCTTTAATGCATCCTCTTTCTAAAGTGGCTAATTCTTTGCTTAAAAAGGCGCTTCCTTTGTCTTGTATCAAGGCTTGATACATTTTAGGGCTGAGTAAATTTTTCGCCAAGTCTAAATTTTCATAGATTTTTTCCAAGCTCCCTAATCGCTGCAACAATTCCTTAGCGTTCTTGCTCCCAATGCCTTTAACCCCCTTGTAATTATCGCTGCTATCCCCCACAATGCCCTGATAATCCGTGAATTGACTCGGCAAAATCCCGTATTTTTCCACGCAATCTTTCGCCAAAAACTCCGTTTTGCCATCAAAAAGCGCGATTTTATCGCTCAAAAGCTGGTTAAAATCCTTATCTTTAGAATAAATGCGGGTTTTATAAGGGCTTAGCGTGGCTAAACTTGCGATCACATCATCGGCTTCAAACCCTCCCACCTCCACGCAAGTAAAACCCATTTTTTGCAACCATTCTAAGGCGATAGGGATTTGTAAAAGCATCTCTTTAGGGGCGTCTTTACGATTTTGTTTGTATTCGCCCAGTTTTTCAGCTCTTTTAGTTTTAGTCTGGCTTTCTAGGGCGAACACGATAAAAGGCATGTTTTTTCTGTCTTTATAAAATTTTTTAACCATGCCCACAAGCCCCGTTAAAAGCCCTGTAGGAAAGCCCTTATCGTTGGTTAAAGGCTTATTTTTAGCGCTCATGTAATAGCTTCTAAACAAATACGCAAAGGTATCAATTAAAGCTAAAGTCCCTTCTTTAATGACTGGCTGCTCCATTCAATCCCTTTTTAATCAAGCGAATTTTAAGTTTATTGTAACACAAGCTGGACCTCATCTATTTCAAAATAACGAGTCTTTTTGAATAGGCGTTTCTTGGCTGATAACTTCTTTTGTAGCCTGTATTTTAGCGTCGCAGTATTGAACCACGCCTTGAATGGTTTGCTTCATCAGGGCGTTGATTAGGGTGTGCATGAAATCAAAATCAATACCATCAAGGCTTTGAGTTTTAGCGGTGGGTTTTAGGGGTAGTTGGATTTTTTGCTCCCTAAAAGTTTTATCAATATCCCTAACTAATACACTCAATAAAGGGCGTTTTAAGGCGTTTAAAAGCGTTGTGAAATAGTGGGCTATGCGTGAATTAATTTTATTTTTAATTTCAGTTTTTGGTGTGATTTTTCGCATGAATTGTCCCGCATACCATGACTTTTTACGATAGAAAAAATCCATTTGCAAAAGCCCTAAACTCCAAGTAAATGGTGGGTTTAAATTTTCTGCATTGACAAATCCTGTAGTTTGCAAAACGCCTTGATTTTGCGAAGTTCTTGTAATATAATCGTAATCTTGTCCTTGCGTTAAAGCGTCTTTATTAAAGCTTAAGGTTTTTTCAATTTCAAACAAATCCCCTAATTTGAAGTGTTGCCATGTCAAGCCGCATGGGGTATTACCCCCCCCCCCCCCAGAATTATTGAAAACATTAAGGGCATTTTCTTCATCGTTAGAAAGGGTGGTGTTTTCTAGCCCTGTAGCTTTTAAATAAGCCTGAAGTTCGGCGAGCCGACACTGCTCAAGTTCGGCTATGAATTTTTCCATGAAATCAAAATCAATACCCTCAAGGGTTTGAGTGTTAGCGGTGGGTTTTAGGGGTAGAATGACTTTATCGTTTTTAATTTTTGCCCATGAACACATGTTTTCATAGCCGAATTTTTTATGGTAACCAAAAAATAGCGTGGATAAAAACAAGCCGATTTTATGGTTGATTTCAAATTTAGGTTTGAGAGAAAATACCCTAGCATGTGTTACCATTTTATAAGCAAAACTGCGATAAAACGCGCAACCAAACATGTCAATAGTAATGGTATGGCTTTCAAAAACTTTTGCTTTTATATCGCTTTGCCCTAAAACGCCATTATTGCTAAGCCCTGCGGTGATGACAAATTCGCCCTTATGATTGATGTGGCGTTTTTGAATGTCAAAATCGCCGTTACTCGCTTCAAACAAATCCCCTAATTTGAACTCGCCCCACTTAATAGCGTTGAGTTGGCTGCTAAGGGGGCCAATCACTTTGGGGGCGTTTGGTTTTTTAAAATCAAACCCACTTCATAAGAAAGGTAATCGGCTATCGTTCTTTTAAAATCCTCCAATTCGGGTTTGGTGTCGGTGGGTTTGTTTTGGTTCCAGTCGCTCCCGTTTTTGGGGTCTATGGTGTTTTCATAGTAGTCATCTTCGCTTAAAAATTTCAAACATGATTGGCCAATATGGACTAAATCCACGACTTCGTTGTAGCGCTCTTTGGCGTTATGCGTGTCTTTTAAATTGTGGCTGGCTTTGGCTTTTTTGCGATTCGCTCTAGCGTAGCCGTCGTTACTGAAATTAATAAATTTCACCCTTTGCTTAGCATCATGCTTTTCATTGACCCTAAAAACATAGATGTGGGTTTGAACGCTGCTTTTGCCGATAAATAAATCTAAAGGCATTTTAATGCTCGCTAAAAGCGTGTGTTTTTCTAAAATCCTTACATTGTATTCTTTGGCTTTACCGCTGCCGGCGCTTGATTGGATGATCACGCTCGCATAACCGCTTTGCATTTTTTCTAAAGCCTGCTCCACAAACACCATGCCATTACCGGGAGCGGAATAAGGCGGGTTTAAAACAAAAGCGTTAGCTTTAAACTCTTTGTCATTGACTTTGCCATCAAAACCGCTCAAGCTGTCTTGGTTTAAGATTTGACTGCTCCCATCGCCCATTAAAATCATGTTTAACACCGCTAGAATATGGATATCCGGTAAGATTTCTATGCCTAAAAGTTGCTTGGCTTTAATGTGGGCGATTTTTTGCTCTAATTCCTCTGGGCTGGTGATACGCTTTTTAGCGTCTTCTATCATCAAATTCATGCTTGCGACTAATAACCCAGCACTCCCGGTAGCAAAATCCCACACGAAACTATCCTTATTGACTTTGGAGAGTCTGGCTAAAAGCGTGGCGACATAAGGGGGTGTGAGCACCACATCGTTTAATTTATCTTGCGTGAAACCCAACCAGCGATACATTTCATTGAACAATTTACCGGTAAAATCCGTGCTAAGACCGATTTTATAATAAACGCCCAAATTATCTACAATCTCACTAAAACAGCGCTTCAAACGGCTTTCGCCATTAATGGCTTTGTTGTTGTTTTCGTTTTTTAATAAAGGCTCTAATGAAGAAATAATGCTTTCCCTTTTCTCTAAAGGCAACTGCTTACGCTCTAAAAAGGATCGGATTTTTCTAAGTATTTTATCACCATCTCTTTCTCCGTTCTCATCGCTGGATTTTAAATCTTCTTTGTTTAGGGGGGCTACCAGATTAGGGATGCCTAAATTAGCGATAATGCTCGCAATCACTAAATATACCCGATTGTGTTCGCTTAAAAAATTCTTTTCTTTGTCATAAATATTGTTATTGAGCTGCATTAAGCAGTCTTCTATTTCTTGGTTTTTCTTTTCTCTAATGCGTTCTAAATCTTCATCGCTTAAAGAAAGGGTGTCTACTCGTTTAATAAAGTCGTTAAAATGCTTACGGCTTAAAAAGGAGAGATCGCTATAAGCTTGCTCGCCTTTTGAAACATCTATCCCCATGCCCAAATTGCTTTTATTCACATAATAGACAGCGATTTGAGAGCGTATGTCGCCTTTATTGTCTTTATAACCTGTGATACCTATGGCGATGCATTCAGTGTAGTCCGTGTGGTGTAAAATCGCATTAGCGTAATGCAAAGCCCCATTTAGGGCGTATTCTCTAATGTTTTTATAATGAGACTCATGGTTTTTAAAATTTTCTACCAGTTTGTTTTTGTCTAATTTAACGAGCTTGTCTTTTAATCCTTTGTATTCTATTAAAACAGGGATTCTTCTGTTAGGGTATTGTGTGTTTAATAAAAGTTTCACATCAGGGCGGTTACCCCCTAAACCCCAACTTTTAGAAGCGTAATTTTTTAAAGCTTCATCAATTTCTGTATTCAGGCTTTCTTGCTCTAGTTTGTATTCTAGGTTATAACTTCTTAACTCGTTGTTGAACTTATCAGCAATTAGAGGCTCAATAGATTGAACTTTATTCATGGGTATCCTTTTTAAAAAATAAAATTATAACTCATTCATCCGCGCTGCAAAGCGCGATCGCAAAGTGCGCTTTGATGTTTAGGGTTTTAAGGTATTTTAGGGCTTCTTTTAGGGTGGTGCCGGTGGTGATAATATCATCTAGCAAGAAATAATCTAAACTTTCATCGCCCCTGAAAGTGAAATTCCGTGGGTTATTGGCGCGAAATTCTAAGCTTTTCCCGGCATACGAAACAGCATTATTAGCCCTTAAACGCCCGTAAGTGGCTTTTAAATTCCCTTGACAAAAGCCTTTTAAAAGCGCGGCGGAATGCGAGTAAAAGGATTTGATTTTATCGTCAATGGCGATGCCATAAAGGGGGGTATTCAAGCCTTGTTCTTGCAGGATTTTCACAAATTCCGCGCCGGCTTTTTGAGAAAGCAAGGGTAAAATGCGAGAGCCAATCAGCGCGTATTTGCTTTTAATAAGCTCTTCTATTTCGCTATAAGCGTAAAAACTATACACGCTCACGCCCTCTAAAACCCTTAACTTTAAGCTTAAGGGCAAATCGTTCAGGCAATTTGGGCAAAGGGGCTTAAAGGAAAGCTTCAAACAGGTTAAACAACGCATTCAATAAAGGTGGCGATTTTTTCGTGCAAGTTTTTAGCGCTTTTTTGAGCGTCTAATTCCAAAACTTCGCACCCGAATTTTTCTTGTAACGCATAAGCGTGGGTTTTGAGCTTTTGCTGGATGGTGAGCAATTTTTCTATGCCTTGGTTTTCTATTTTGTCTAAACTTTTAAGGCTTAAGCGCTGTTTTAAGTTCTCTTTATTTATGAGTAACAGAATGATTTTTTCAGGTAAGACGCTTTGAGTGGCGAGCAGGTTTAATTCTAAGCTTGAAAATTGGCTATAAGCCATGCCAGAAATCAAACTCCTGTCGCTAATGATGAGCTTTTTTTCTTTCAATGCCGGTTTTATCACGCTTTCTATATGCTCAGCCCTATCGCTTAAGAATAAAAACGCTCTAGCCAATTCGCTGATGTTTTCATTTAAAGCGATACGCCTTAAACTCTCGCCCATTCTCGTCCCCCCTGGCTCTTTGGTAAAAAGGGCGTTTTTAAACCGGTCTTTTAACAATCCTACTTGAGTGCTTTTGCCCGCGCCATCAACGCCTTCTAACACCACATACATTTTTTAAACCTTTGAAATAAAAGGGTAAATTTCTTTAGGCACTAAATGGCTCGCATCGCCCTTATGCGCGATAATGGATCGCACGATAGAAGAGCTGATGAAAGCGTTTTGTAAAGTGGGCATGAAATACAAGGTCTCTAATTCGTGGTTTAAGGATTTGTTCGCATAGCCCATTTGCAATTCGTATTCAAAATCGCTCACCACCCTTAAGCCCCTAACTAGCACTTTGCAATGATACTCTTTAGCCAGATCGGCTAATAGCCCCTCAAACGCAACGCATTCTACATTTTTAAAACTTTTAGTGGCCAGTTGCATCATTTTTAAGCGCTCATCTAAACTAAACATGGGGTTTTTAGCGCTTGAGTGCGCCACAGCCACAATGAGCTTTTCAAACAATTCGCTGGATCGGTGGATGATGTCTATATGCCCGTTAGTGACCGGATCAAAAGTGCCCGGGTAAATGCCGATTTTTTGCATCAGTTCATTCCCCATCGTGGGTATAAGTCATTTTCTATTCCCAAGCTGTCAAACCACTTCCCCACTAAAAAATCTTGCATCGCTTCTAAAGTCTTGCTCTGGGTATAATAAGTCATCATCGGCGGCGCGATGATCGCATTAGAATGGGCGAGTTTGAGCAAATTTTCTAACATGATAGCGCTTAAAGGCATTTCTCTAGGGGCAATGAGTAAGGGGCGCTTTTCTTTCAGCATGACAGAGGCGCTCCTAGAAATCAAATCCCCCCCAAAGCCATGCGCGATTTTAGCCACCATGTCCATGCTCGCTGGAATGATCGCCATTTTATGGATACCATAACTCCCTGAGGCGATGCTCGCATGGATGTCTTGCTCGTTAAAAAAAGTCGCGCTAGGCCGTAAGTCTTTCATGGCGTTTTTAAGGTTGATGTTAGATTCTTCTAACGCCACGACATGCGCGTTTTTAGACGCCACGACAAAAATTTCAATTTCTTTAGGTAATTTCTCTAAAAACCGCAAGGCTAGGGGTATCCCGCTCGCCCCGCTGATGCCTAAAACTAATTTCATGAATATCCTTTATAAGATTTGCGCTTTAGAGCTGCTCAACACTTTCGCTTTTAAGATTTTATTGCTTTCTAAATTCTTCGCTTGAATGATTTGATGGAGCGCGCCATTTTCTAGGGCTTTTAGGCTTATTTCTATGCTGATTTGCCCCTCTTCATACACCCCAGTGATAATGTCGTTTTTACGCACGATGATTAAAGCTTGGGTTTTATCTGCGCTTAAAAGCGTGTCAGGGGGGATGAAATGTTTCGCGCTCACTTTATCGATCGCACCCTCTAATAAGGGGTTAGAAAGCGCGCCAAACAAAACGCGCTCTTTTTTAGTGTTGTTGGCGGTGATGTTCTCGTCTTTTTTAATCGTGCTAGCGCTTTTAAAAGCTTGCATGCTGCCTATCACGCTATAACGCACCGGTAGGCGTAAATTAGGCTCATTTTCCAATCTTAAAAACACGACCCCATCTTTTTTAAGCTTGTTAGAAGCGTTCAATTCATAGCTTAAAATGGAAGCGTGAGAAAAACGCTCTGGGATTTCTAAATTAATTGTTTCAATTTCCAATTTTAAGTCTTTGTATTCTTTGAGATAGGTTTCTTTGATTTCTGTTTTAAGCGCGTTCAAATCTAGGGCGAACAATGCGTTTAAACCTATCAAAAAAAGGGTTAAAATTTTCAAAACTCGTTATCCACTTTTTCTACAAATTTTTCTGAAATTTTATCATAGACATTCCCTCCGCAATTGATTTTCAAGCACAAACCGCTCAAGCCTTTTTCTACGCCTAAAACCCTCCCGGTGCCAAAAATCTTATGTTTGATCAAATCCCCCACTTTAATGGGCGTATCTTTTTGGTGATTTTGTTTAGGAGGCTTGTCTTGTTGGAGCAACTGGGCTTCTTCTAAAAACACAGAGGGCGAGCAAGAAATTTTCCTCCCAAAATACGAACGCTCTTTGACATAAGAAAGTTGTAATTCTTCTTTAGCCCTAGTGATCGCCACGTAAGCCAAGCGCCTTTCTTCTTCCAAATCGCTTTCTTGATTGAACCCCCTATGCGGGAAAAACCCCTCTTCTAACCCGATCACAAACACATGCTTAAACTCTAAGCCCTTACTCATATGCACGCTCATGCAACTCACTTTTTGCGCGTTTTCTGTATTATGGACATCCAGTGCGCTTTCATTCAAAAAATCCAGTAAAGAATGCGTGGGGTTAGTTTTAAAATGCTCTTTCACTAAACTTAAAAGCTCTTTAACAAAGCCCTCTCTTTCTTCGTAATTGTCTTCTTTTTCATAGCTTTTTAAAAGGTTAGTCTCTTCTAAAAACCGCTCGCAAAACTTCTCTACTGAAATTTCAAAAGCCTCCCTCAAACGCCCTATCATAGCGGTGAATTTCTTTAAAGCGTATTCGTTTTTAGGGTTGAGTTTGTCTTTAAACGCCCCAATTTTTAGCGCTTCTTCTAAATTCAAACCCTCTTCATCTAAAAGAGAAAAAATCCATTCTTGAGTGATCTTGCCAAGGCCTCTTGGGGGCTTGTTTAAAACGCGTTTAATAAAAAAGCGATCGTCTTTTTTCGCCACCACATGCATGAGTGCCAAAGCGTCTTTAACCTCGGCTCTTTCATAGAAACTCACCGCACCAATGAGCCTATAAGGGATATTCAAAGCGTTCAAGCTCTCTTCAATGCTGCGGCTAAGCCCATTTAAACGATACAAAATAGCGATATTTTCTAAATTCTCGCCCTTCTTTAAAAGGGCTTTGATCTGATAAGCCACATCCAGGCTCTCTTCTTTTTGCGTGGGGTATTCTTTACAAATCACGCTTTTGTGCGAACCTTTGAAACTTTGAAGCGTTTTAATGTGGCGGTGTTGGTTATGGCTGATCAGGGAATTAGCGCACGCTAAGATTTCAGCGCTAGAGCGGTAGTTGGTCTCTAATTTCACTATTTTAGCCCCTTTAAAATGCTTGGAAAAATTTAAAATGTTAGAAATATCAGCCCCCCTAAACCCATAAATGCTCTGATCGTCATCGCCCACCACGCACAAATTATGGTGCGTGAAACTCAATTGTTTTAAAAATTCCAGTTGCAGGGCGTTCGTGTCTTGATACTCATCTACCATAATGTAATGGTAGCGTTCGCTGGTCTCTTTGGCGAGTTTTTCATTATCTTGTAAAATCTTAAGGCTCAAACAAAGCAAATCGTCAAAATCCACTAAATTGTCTTTTTTGAGCGCGTTTTGATAAAGCTCATACGCTTTGTAACATTCGCTATCTTGCACGCTCAAATCCATCATGCCGTTTTTGATTTGAGAAATGCTCGCCCTGAAATTTGAAATTTTGAGCTGTTTGCAGAGCGTTTTCACTTCATCGCTATCTAGCACCGAAAAATCGCACGCCCTTTTTAAAAGATTCATGTGTTGCCTTAAAAACAGCAAACCAAAACGATGGAAAGTGCAAAGCAAGGGGGGGATAAGGGCTTGGTTTTTCAACAATTTCAAAGCCCTTTCTTGCATTTCTTTACTCGCTTTATTGGTGAAAGTGAGCGTTAAAGTGTTTTCGCTAGGCACGCCACAAGCGCCAATCAAATACGCTAAACGGCTCGTTAAAGTCTTAGTCTTACCGCTCCCAGCTCCCGCTAAAATCAATAAAGGCCCTTGAATGTGGCATGCGGCAATTTTTTGCGCTCCGTTCAAATTGTCTAAAATGCTTTTTTCAAAACCCATTAT

Protein sequences of DBSCAN-SWA_1

>NC_000921|1492475:1503407|1500705_1501362_-|WP_000699043.1|DBSCAN-SWA
MKILTLFLIGLNALFALDLNALKTEIKETYLKEYKDLKLEIETINLEIPERFSHASILSYELNASNKLKKDGVVFLRLENEPNLRLPVRYSVIGSMQAFKSASTIKKDENITANNTKKERVLFGALSNPLLEGAIDKVSAKHFIPPDTLLSADKTQALIIVRKNDIITGVYEEGQISIEISLKALENGALHQIIQAKNLESNKILKAKVLSSSKAQIL
>NC_000921|1492475:1503407|1496449_1498486_-|WP_001045380.1|DBSCAN-SWA
MNKVQSIEPLIADKFNNELRSYNLEYKLEQESLNTEIDEALKNYASKSWGLGGNRPDVKLLLNTQYPNRRIPVLIEYKGLKDKLVKLDKNKLVENFKNHESHYKNIREYALNGALHYANAILHHTDYTECIAIGITGYKDNKGDIRSQIAVYYVNKSNLGMGIDVSKGEQAYSDLSFLSRKHFNDFIKRVDTLSLSDEDLERIREKKNQEIEDCLMQLNNNIYDKEKNFLSEHNRVYLVIASIIANLGIPNLVAPLNKEDLKSSDENGERDGDKILRKIRSFLERKQLPLEKRESIISSLEPLLKNENNNKAINGESRLKRCFSEIVDNLGVYYKIGLSTDFTGKLFNEMYRWLGFTQDKLNDVVLTPPYVATLLARLSKVNKDSFVWDFATGSAGLLVASMNLMIEDAKKRITSPEELEQKIAHIKAKQLLGIEILPDIHILAVLNMILMGDGSSQILNQDSLSGFDGKVNDKEFKANAFVLNPPYSAPGNGMVFVEQALEKMQSGYASVIIQSSAGSGKAKEYNVRILEKHTLLASIKMPLDLFIGKSSVQTHIYVFRVNEKHDAKQRVKFINFSNDGYARANRKKAKASHNLKDTHNAKERYNEVVDLVHIGQSCLKFLSEDDYYENTIDPKNGSDWNQNKPTDTKPELEDFKRTIADYLSYEVGLILKNQTPPK
>NC_000921|1492475:1503407|1499659_1500133_-|WP_001169238.1|DBSCAN-SWA
MQKIGIYPGTFDPVTNGHIDIIHRSSELFEKLIVAVAHSSAKNPMFSLDERLKMMQLATKSFKNVECVAFEGLLADLAKEYHCKVLVRGLRVVSDFEYELQMGYANKSLNHELETLYFMPTLQNAFISSSIVRSIIAHKGDASHLVPKEIYPFISKV
>NC_000921|1492475:1503407|1498517_1499093_-|WP_001203557.1|DBSCAN-SWA
MRCLTCLKLSFKPLCPNCLNDLPLSLKLRVLEGVSVYSFYAYSEIEELIKSKYALIGSRILPLLSQKAGAEFVKILQEQGLNTPLYGIAIDDKIKSFYSHSAALLKGFCQGNLKATYGRLRANNAVSYAGKSLEFRANNPRNFTFRGDESLDYFLLDDIITTGTTLKEALKYLKTLNIKAHFAIALCSADE
>NC_000921|1492475:1503407|1495232_1496453_-|WP_000580077.1|DBSCAN-SWA
MIGPLSSQLNAIKWGEFKLGDLFEASNGDFDIQKRHINHKGEFVITAGLSNNGVLGQSDIKAKVFESHTITIDMFGCAFYRSFAYKMVTHARVFSLKPKFEINHKIGLFLSTLFFGYHKKFGYENMCSWAKIKNDKVILPLKPTANTQTLEGIDFDFMEKFIAELEQCRLAELQAYLKATGLENTTLSNDEENALNVFNNSGGGGGNTPCGLTWQHFKLGDLFEIEKTLSFNKDALTQGQDYDYITRTSQNQGVLQTTGFVNAENLNPPFTWSLGLLQMDFFYRKKSWYAGQFMRKITPKTEIKNKINSRIAHYFTTLLNALKRPLLSVLVRDIDKTFREQKIQLPLKPTAKTQSLDGIDFDFMHTLINALMKQTIQGVVQYCDAKIQATKEVISQETPIQKDSLF
>NC_000921|1492475:1503407|1492475_1495169_-|WP_000437564.1|DBSCAN-SWA
MEQPVIKEGTLALIDTFAYLFRSYYMSAKNKPLTNDKGFPTGLLTGLVGMVKKFYKDRKNMPFIVFALESQTKTKRAEKLGEYKQNRKDAPKEMLLQIPIALEWLQKMGFTCVEVGGFEADDVIASLATLSPYKTRIYSKDKDFNQLLSDKIALFDGKTEFLAKDCVEKYGILPSQFTDYQGIVGDSSDNYKGVKGIGSKNAKELLQRLGSLEKIYENLDLAKNLLSPKMYQALIQDKGSAFLSKELATLERGCIKEFDFLSCAFPSENPLLKIKDELKEYGFISTLRDLENSPFIVENVPILNSTPILDNTPALDNAPKKSRMIVLESAEPLSMFLEKLENPNARVFMRLVLDKDKKILALAFLLQDQGYFLPLEEALFSPFSLEFLQNAFSQMLQHACIIGHDLKPLLSFLKAKYQVPLENIRIQDTQILAFLKNPEKVGFDEVLKEYLKEDLIPHEKIKDFKTKSKAEKSELLSMELNALKRLCEYFEKGGLEEDLLTLARDIETPFVKVLMGMEFQGFKIDAPYFKRLEQEFKNELNVLERQILDLIGVDFNLNSPKQLGEVLYDKLGLPKNKSHSTDEKNLLKILDKHPSIPLILEYRELNKLFNTYTTPLLRLKDKDDKIHTTFIQTGTATGRLSSHSPNLQNIPVRSPKGLLIRKGFIASSKEYCLLGVDYSQIELRLLAHFSQDKDLMEAFLKGRDIHLETSKALFGEDLAKEKRSIAKSINFGLVYGMGSKKLSETLSIPLSEAKSYIEAYFKRFPSIKDYLNGMREEILKTSKAFTLLGRYRVFDFTGVNDYVKGNYLREGVNAIFQGSASDLLKLGMLKVSERFKNNPSVRLLLQVHDELIFEIEEKNAPELQQEIQRILNDEVYPLRVPLETSAFIAKRWNELKG
>NC_000921|1492475:1503407|1501358_1503407_-|WP_079993041.1|DBSCAN-SWA
MMGFEKSILDNLNGAQKIAACHIQGPLLILAGAGSGKTKTLTSRLAYLIGACGVPSENTLTLTFTNKASKEMQERALKLLKNQALIPPLLCTFHRFGLLFLRQHMNLLKRACDFSVLDSDEVKTLCKQLKISNFRASISQIKNGMMDLSVQDSECYKAYELYQNALKKDNLVDFDDLLCLSLKILQDNEKLAKETSERYHYIMVDEYQDTNALQLEFLKQLSFTHHNLCVVGDDDQSIYGFRGADISNILNFSKHFKGAKIVKLETNYRSSAEILACANSLISHNQHRHIKTLQSFKGSHKSVICKEYPTQKEESLDVAYQIKALLKKGENLENIAILYRLNGLSRSIEESLNALNIPYRLIGAVSFYERAEVKDALALMHVVAKKDDRFFIKRVLNKPPRGLGKITQEWIFSLLDEEGLNLEEALKIGAFKDKLNPKNEYALKKFTAMIGRLREAFEISVEKFCERFLEETNLLKSYEKEDNYEEREGFVKELLSLVKEHFKTNPTHSLLDFLNESALDVHNTENAQKVSCMSVHMSKGLEFKHVFVIGLEEGFFPHRGFNQESDLEEERRLAYVAITRAKEELQLSYVKERSYFGRKISCSPSVFLEEAQLLQQDKPPKQNHQKDTPIKVGDLIKHKIFGTGRVLGVEKGLSGLCLKINCGGNVYDKISEKFVEKVDNEF
>NC_000921|1492475:1503407|1499080_1499656_-|WP_000289745.1|DBSCAN-SWA
MYVVLEGVDGAGKSTQVGLLKDRFKNALFTKEPGGTRMGESLRRIALNENISELARAFLFLSDRAEHIESVIKPALKEKKLIISDRSLISGMAYSQFSSLELNLLATQSVLPEKIILLLINKENLKQRLSLKSLDKIENQGIEKLLTIQQKLKTHAYALQEKFGCEVLELDAQKSAKNLHEKIATFIECVV
>NC_000921|1492475:1503407|1500132_1500696_-|WP_000780089.1|DBSCAN-SWA
MKLVLGISGASGIPLALRFLEKLPKEIEIFVVASKNAHVVALEESNINLKNAMKDLRPSATFFNEQDIHASIASGSYGIHKMAIIPASMDMVAKIAHGFGGDLISRSASVMLKEKRPLLIAPREMPLSAIMLENLLKLAHSNAIIAPPMMTYYTQSKTLEAMQDFLVGKWFDSLGIENDLYPRWGMN

Homologous phage analysis in the prophage region

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000437564.1|1492475_1495169_-	DNA polymerase I	A0A218MKQ4	uncultured_virus	3.8e-60	33.3
WP_000580077.1|1495232_1496453_-	restriction endonuclease subunit S	A0A1W6JNN3	Staphylococcus_phage	3.7e-07	25.6
WP_001045380.1|1496449_1498486_-	N-6 DNA methylase	A0A2H4JBT5	uncultured_Caudovirales_phage	8.3e-76	34.3
WP_001203557.1|1498517_1499093_-	ComF family protein	NA	NA	NA	NA
WP_000289745.1|1499080_1499656_-	dTMP kinase	Q2XUX0	environmental_halophage	1.0e-10	38.6
WP_001169238.1|1499659_1500133_-	pantetheine-phosphate adenylyltransferase	A0A1B1IVQ3	uncultured_Mediterranean_phage	3.3e-28	45.5
WP_000780089.1|1500132_1500696_-	UbiX family flavin prenyltransferase	NA	NA	NA	NA
WP_000699043.1|1500705_1501362_-	flagellar basal body P-ring formation protein FlgA	NA	NA	NA	NA
WP_079993041.1|1501358_1503407_-	DNA helicase UvrD	A7KV33	Bacillus_phage	1.8e-91	35.3