CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NC_009332	Streptococcus pyogenes str. Manfredo, complete genome	2 crisprs	DEDDh,cas3,DinG,csa3	0	0	8	0

Results visualization

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CRISPR-Cas detection and classification

Crispr_ID: NC_009332_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_009332_1

819458-819558

Orphan

Consensus_repeat	Method
TATAATTAGACTATACCAATTTT	CRISPRCasFinder

1 spacers

The CRISPR arrays of NC_009332_1

>merge|NC_009332|1|819458-819558|CRISPRCasFinder
TATAATTAGACTATACCAATTTTATGTTTGACAAGACATTGTGGATATTATATACTGTAAACATAATGTTTTTATCGGTATAATTAGACTATACCAATTAT

>NC_009332|1|1|819458-819558|CRISPRCasFinder
TATAATTAGACTATACCAATTTT	ATGTTTGACAAGACATTGTGGATATTATATACTGTAAACATAATGTTTTTATCGG
TATAATTAGACTATACCAATTAT

Protein	Signature genes	Signature genes Name	Protein_function
NC_009332.1\|WP_011888832.1\|812890_816001_+\|DNA-polymerase-III-subunit-alpha	unknown	unknown	gnl\|CDD\|180917
NC_009332.1\|WP_002984447.1\|817156_818659_+\|pyruvate-kinase	unknown	unknown	gnl\|CDD\|235619
NC_009332.1\|WP_002984449.1\|818876_819434_+\|signal-peptidase-I	unknown	unknown	gnl\|CDD\|274044
NC_009332.1\|WP_011888835.1\|825707_826943_-\|cation-diffusion-facilitator-family-transporter	unknown	unknown	gnl\|CDD\|223131
NC_009332.1\|WP_002984444.1\|816080_817094_+\|6-phosphofructokinase	unknown	unknown	gnl\|CDD\|235111
NC_009332.1\|WP_002984437.1\|811636_812335_-\|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|224054
NC_009332.1\|WP_011284831.1\|828913_831232_+\|DNA-helicase-PcrA	unknown	unknown	gnl\|CDD\|273429
NC_009332.1\|WP_011888830.1\|806218_808483_+\|glycogen/starch/alpha-glucan-family-phosphorylase	unknown	unknown	gnl\|CDD\|340853
NC_009332.1\|WP_011017835.1\|810841_811627_-\|hypothetical-protein	unknown	unknown	unknown
NC_009332.1\|WP_002989617.1\|812334_812706_-\|GntR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|224639
NC_009332.1\|WP_002989607.1\|810100_810715_+\|TVP38/TMEM64-family-protein	unknown	unknown	gnl\|CDD\|223475
NC_009332.1\|WP_002984469.1\|831594_831843_+\|GlsB/YeaQ/YmgE-family-stress-response-membrane-protein	unknown	unknown	gnl\|CDD\|225170
NC_009332.1\|WP_011888833.1\|819609_821424_+\|glutamine--fructose-6-phosphate-transaminase-(isomerizing)	unknown	unknown	gnl\|CDD\|234729
NC_009332.1\|WP_002984455.1\|822061_822703_+\|amino-acid-ABC-transporter-permease	unknown	unknown	gnl\|CDD\|223836
NC_009332.1\|WP_011528695.1\|821619_821955_+\|alkylphosphonate-utilization-protein	unknown	unknown	gnl\|CDD\|225380
NC_009332.1\|WP_011888831.1\|808739_809360_-\|DUF3862-domain-containing-protein	unknown	unknown	gnl\|CDD\|289729
NC_009332.1\|WP_002984465.1\|827062_828385_-\|sodium:alanine-symporter-family-protein	unknown	unknown	gnl\|CDD\|224040
NC_009332.1\|WP_002984457.1\|822712_823342_+\|amino-acid-ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|224051
NC_009332.1\|WP_011888834.1\|824564_825338_+\|CAMP-factor-pore-forming-toxin-Cfa	unknown	unknown	gnl\|CDD\|369335
NC_009332.1\|WP_002984460.1\|823357_824194_+\|amino-acid-ABC-transporter-substrate-binding-protein	unknown	unknown	gnl\|CDD\|270217

Protein	Function_ID	Function_description	E-value
NC_009332.1\|WP_011888832.1\|812890_816001_+\|DNA-polymerase-III-subunit-alpha	gnl\|CDD\|180917	PRK07279, dnaE, DNA polymerase III DnaE; Reviewed.	0
NC_009332.1\|WP_002984447.1\|817156_818659_+\|pyruvate-kinase	gnl\|CDD\|235619	PRK05826, PRK05826, pyruvate kinase; Provisional.	0
NC_009332.1\|WP_002984449.1\|818876_819434_+\|signal-peptidase-I	gnl\|CDD\|274044	TIGR02227, Inactive_signal_peptidase_IA., signal peptidase I, bacterial type. This model represents signal peptidase I from most bacteria. Eukaryotic sequences are likely organellar. Several bacteria have multiple paralogs, but these represent isozymes of signal peptidase I. Virtually all known bacteria may be presumed to A related model finds a simlar protein in many archaea and a few bacteria, as well as a microsomal (endoplasmic reticulum) protein in eukaryotes. [Protein fate, Protein and peptide secretion and trafficking].	2.3728e-38
NC_009332.1\|WP_011888835.1\|825707_826943_-\|cation-diffusion-facilitator-family-transporter	gnl\|CDD\|223131	COG0053, MMT1, Predicted Co/Zn/Cd cation transporters [Inorganic ion transport and metabolism].	3.5462e-96
NC_009332.1\|WP_002984444.1\|816080_817094_+\|6-phosphofructokinase	gnl\|CDD\|235111	PRK03202, PRK03202, ATP-dependent 6-phosphofructokinase.	0
NC_009332.1\|WP_002984457.1\|822712_823342_+\|amino-acid-ABC-transporter-ATP-binding-protein	gnl\|CDD\|224051	COG1126, GlnQ, ABC-type polar amino acid transport system, ATPase component [Amino acid transport and metabolism].	1.89978e-111
NC_009332.1\|WP_011284831.1\|828913_831232_+\|DNA-helicase-PcrA	gnl\|CDD\|273429	TIGR01073, ATP-dependent_DNA_helicase_PcrA, ATP-dependent DNA helicase PcrA. Designed to identify pcrA members of the uvrD/rep subfamily. [DNA metabolism, DNA replication, recombination, and repair].	0
NC_009332.1\|WP_011888830.1\|806218_808483_+\|glycogen/starch/alpha-glucan-family-phosphorylase	gnl\|CDD\|340853	cd04300, GT35_Glycogen_Phosphorylase, glycogen phosphorylase and similar proteins. This is a family of oligosaccharide phosphorylases. It includes yeast and mammalian glycogen phosphorylases, plant starch/glucan phosphorylase, as well as the maltodextrin phosphorylases of bacteria. The members of this family catalyze the breakdown of oligosaccharides into glucose-1-phosphate units. They are important allosteric enzymes in carbohydrate metabolism. The allosteric control mechanisms of yeast and mammalian members of this family are different from that of bacterial members. The members of this family belong to the GT-B structural superfamily of glycoslytransferases, which have characteristic N- and C-terminal domains each containing a typical Rossmann fold. The two domains have high structural homology despite minimal sequence homology. The large cleft that separates the two domains includes the catalytic center and permits a high degree of flexibility.	0
NC_009332.1\|WP_002984437.1\|811636_812335_-\|ABC-transporter-ATP-binding-protein	gnl\|CDD\|224054	COG1131, CcmA, ABC-type multidrug transport system, ATPase component [Defense mechanisms].	7.28377e-64
NC_009332.1\|WP_002989617.1\|812334_812706_-\|GntR-family-transcriptional-regulator	gnl\|CDD\|224639	COG1725, COG1725, Predicted transcriptional regulators [Transcription].	4.0536e-49
NC_009332.1\|WP_002989607.1\|810100_810715_+\|TVP38/TMEM64-family-protein	gnl\|CDD\|223475	COG0398, COG0398, Uncharacterized conserved protein [Function unknown].	1.14841e-31
NC_009332.1\|WP_002984469.1\|831594_831843_+\|GlsB/YeaQ/YmgE-family-stress-response-membrane-protein	gnl\|CDD\|225170	COG2261, COG2261, Predicted membrane protein [Function unknown].	1.43969e-13
NC_009332.1\|WP_011888833.1\|819609_821424_+\|glutamine--fructose-6-phosphate-transaminase-(isomerizing)	gnl\|CDD\|234729	PRK00331, PRK00331, isomerizing glutamine--fructose-6-phosphate transaminase.	0
NC_009332.1\|WP_002984455.1\|822061_822703_+\|amino-acid-ABC-transporter-permease	gnl\|CDD\|223836	COG0765, HisM, ABC-type amino acid transport system, permease component [Amino acid transport and metabolism].	1.36474e-71
NC_009332.1\|WP_011528695.1\|821619_821955_+\|alkylphosphonate-utilization-protein	gnl\|CDD\|225380	COG2824, PhnA, Uncharacterized Zn-ribbon-containing protein involved in phosphonate metabolism [Inorganic ion transport and metabolism].	2.87366e-64
NC_009332.1\|WP_011888831.1\|808739_809360_-\|DUF3862-domain-containing-protein	gnl\|CDD\|289729	pfam12978, DUF3862, Domain of Unknown Function with PDB structure (DUF3862). Structure 3D4E shared structural similarity to beta-lactamase inhibitory proteins (BLIP) which already include 1XXM, 1S0W, 1JTG, 2G2U, 2G2W, 2B5R, and 3due. All of structures are involved in beta-lactamase inhibitor complex. (REF http://www.topsan.org/Proteins/JCSG/3d4e).	4.55552e-87
NC_009332.1\|WP_002984465.1\|827062_828385_-\|sodium:alanine-symporter-family-protein	gnl\|CDD\|224040	COG1115, AlsT, Na+/alanine symporter [Amino acid transport and metabolism].	0
NC_009332.1\|WP_011888834.1\|824564_825338_+\|CAMP-factor-pore-forming-toxin-Cfa	gnl\|CDD\|369335	pfam07373, CAMP_factor, CAMP factor (Cfa). This family consists of several bacterial CAMP factor (Cfa) proteins which seem to be specific to Streptococcus species. The CAMP reaction is a synergistic lysis of erythrocytes by the interaction of an extracellular protein (CAMP factor) produced by some streptococcal species with the Staphylococcus aureus sphingomyelinase C (beta-toxin).	2.3962e-98
NC_009332.1\|WP_002984460.1\|823357_824194_+\|amino-acid-ABC-transporter-substrate-binding-protein	gnl\|CDD\|270217	cd00996, PBP2_AatB_like, Polar amino acids-binding domain of ATP-binding cassette transporter-like systems that belong to the type 2 periplasmic binding fold protein superfamily. This subfamily includes periplasmic binding domain of ATP-binding cassette transporter-like systems that serve as initial receptors in the ABC transport of amino acids and their derivatives in eubacteria. After binding their ligand with high affinity, they interact with a cognate membrane transport complex comprised of two integral membrane domains and two cytoplasmically-located ATPase. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis. The Abp proteins belong to the PBPI superfamily of periplasmic binding proteins that differ in size and ligand specificity, but have similar tertiary structures consisting of two globular subdomains connected by a flexible hinge. They have been shown to bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap.	4.79673e-109

>NC_009332.1|WP_002984449.1|818876_819434_+|signal-peptidase-I
MVKRDFIRNILLLLIVIIGAILLRIFVFSTFKVSPETANTYLKSGDLVTIKKNIQPKYKDFVVYRVGKKDYVSRVIAVEGDSVTYMDDIFYLNNMVESQAYLEKMKAHYLNHAPFGTLYTDDFTVATITADKYQKVPKGKYLLLNDNRKNTNDSRRFGLINASQIKGLVTFRVLPLSDFGFVEVE
>NC_009332.1|WP_002984447.1|817156_818659_+|pyruvate-kinase
MNKRVKIVATLGPAVEIRGGKKYGEDGYWAGQLDVEESAKKIAELIEAGANVFRFNFSHGDHKEQGDRMATVRLAEEIARQKVGFLLDTKGPEMRTELFADDAKEFSYVTGEKIRVATTQGIQSTRDVIALNVAGSLDIYDEVEVGHTILIDDGKLGLKVIDKDIATRQFIVEVENDGIIAKQKGVNIPNTKIPFPALAERDNADIRFGLEQGLNFIAISFVRTAKDVEEVREICRETGNDHVQLFAKIENQQGIDNLDEIIEAADGIMIARGDMGIEVPFEMVPVFQKMIITKVNAAGKAVITATNMLETMTEKPRATRSEVSDVFNAVIDGTDATMLSGESANGKYPVESVRTMATIDRNAQTLLNEYGRLDSSAFPRTNKTDVIASAVKDATHSMDIKLVVTITETGNTARAISKFRPDADILAVTFDEKVQRALMINWGVIPVLAEKPASTDDMFEVAERVAVEAGLVQSGDNIVIVAGVPVGTGGTNTMRVRTVK
>NC_009332.1|WP_002984444.1|816080_817094_+|6-phosphofructokinase
MKRIAVLTSGGDAPGMNAAIRAVVRKAISEGMEVYGINRGYAGMVDGDIFPLGSKEVGDKISRGGTFLYSARYPEFAQLEGQLAGIEQLKKHGIEGVVVIGGDGSYHGAMRLTEHGFPAVGIPGTIDNDIAGTDYTIGFDTAVNTAVEAIDKLRDTSSSHGRTFVVEVMGRNAGDIALWAGIASGADQIIVPEEEFDIEKVASTIQYDFEHKGKNHHIIVLAEGVMSGEAFAQKLKEAGDKSDLRVTNLGHILRGGSPTARDRVIASWMGSHAVELLKEGKGGLAVGIHNEELVESPILGTAEEGALFSLTEEGKIIVNNPHKARLDFAALNRSLSQ
>NC_009332.1|WP_011888832.1|812890_816001_+|DNA-polymerase-III-subunit-alpha
MFAQLDTKTVYSFMDSLIDLNHYFERAKQFGYHTIGIMDKDNLYGAYHFIKGCQKNGLQPVLGLEVEILYQERQVLLNLIAQNTQGYHQLLKISTAKMSGKLHMDYLCQHLEGIAVIIPSKGWSDTLVVPFDYYIGVDQYTDLSHMDSKRQLIPLRTVRYFAQDDMETLHMLHAIRDNLSLAETPVVESDQELADCQQLTTFYQTHCPQALQNLEDLVSGIYYDFDTNLKLPHFNRDKSAKQELQELTEAGLKEKGLWKEPYQSRLLHELVIISDMGFDDYFLIVWDLLRFGRSKGYYMGMGRGSAAGSLVAYALNITGIDPVQHDLLFERFLNKERYSMPDIDIDLPDIYRSEFLRYVRNRYGSDHSAQIVTFSTFGPKQAIRDVFKRFGVPEYELTNLTKKIGFKDSLATVYEKSISFRQVINSRTEFQKAFAIAKRIEGNPRQTSIHAAGIVMSDDTLTNHIPLKSGDDMMITQYDAHAVEANGLLKMDFLGLRNLTFVQKMQEKVAKDYGCQIDIAAIDLEDPQTLALFAKGDTKGIFQFEQNGAINLLKRIKPQRFEEIVATTSLNRPGASDYTTNFIKRREGQEKIDLIDPVIAPILEPTYGIMLYQEQVMQIAQVYAGFTLGKADLLRRAMSKKNLQEMQKMEEDFIASAKHLGRAEETARGLFKRMEKFAGYGFNRSHAFAYSALAFQLAYFKAHYPAVFYDIMMNYSSSDYITDALESDFQVAQVTINSIPYTDKIEASKIYMGLKNIKGLPRDFAYWIIEQRPFNSVEDFLTRAPEKYQKKFFLEPLIKIGLFDYFEPNRKKILDNLDGLLVFVNELGSLFSDSSFSWVDTKDYSATEKYSLEQEIVGVGMSKHPLIDIAEKSTQTFTPISQLVKESEAVVLIQIDSIRIIRTKTSGQQMAFLSVNDTKKKLDVTLFPQEYAIYKDQLKEGEFYYLKGRIKERDHRLQMVCQQVQMAISQKYWLLVENHQFDSQISEILGAFPGTTPVVIHYQKNKETIALTKIQVHVTENLKEKLRPFVLKTVFR
>NC_009332.1|WP_002989617.1|812334_812706_-|GntR-family-transcriptional-regulator
MSWKFDEKSPIYAQIAQHVMMQIISQEIKSGDQLPTVREYAEIAGVNPNTMQRAFTELEREGMVYSQRTAGRFVTDDQKLIARKRRELAISELESFITNMTKMGFSHTEIIPVLTSFLKEDSQ
>NC_009332.1|WP_002984437.1|811636_812335_-|ABC-transporter-ATP-binding-protein
MAHLLQLHHVSKSYREKKAIDDLTITIPNGKIIGLLGPNGSGKTTLIKLINGLLQPNKGEIVIDGYRPCVETKKIISYLPDTTYLNENMRIKDMLEFFSDFYSDFDKSKATSLLRDLELDPEDRFKTLSKGNKEKVQLILVMSRKARLYVLDEPIGGVDPAARDYILKTIINSYCENASVIISTHLISDIEPILDEVIFLKQGRLFLSGNADDLRQEYQQSIDSLFRETYKV
>NC_009332.1|WP_011017835.1|810841_811627_-|hypothetical-protein
MFGKLLKYEFRSIGKWYFALNAFVIAIAAILSFTIKLFAQSNSDGLFGVLTNKMLPLTLGLTFGSLIAGSLLSTLLIIIKRFSKSVFGREGYLTLTLPVNSHQIILSKLLASFICSVFNTIILAFAIAIVIVPMFNVNELLEGFFNSFKMDYFINMLTVLAYVLLSTFTSILLIYLSISIGQLFSNRRGLMAFIAYFILVILISVAATYVHNHIFNINTSADSFPFTEQKTTYLLILEQFIEMIMFYLATNFIIKNKLNLQ
>NC_009332.1|WP_002989607.1|810100_810715_+|TVP38/TMEM64-family-protein
MTKRNSKAYILWQKIIKILGIIALIGTFFLAFWLYRLGILNDSNALKDLVQRYRLWGPFVFIVVQIIQIVFPVIPGGLTTVAGFLIFGPVTGFIYNYVGIIIGSIVLFLLVKTYGRKFILLFVNDKTFYKYERRLETPGYEKLFIFCMASPVSPADIMVMITGLTDMSLKRFVTILLITKPISIIGYSYLFIFGKDVISWFLQH
>NC_009332.1|WP_011888831.1|808739_809360_-|DUF3862-domain-containing-protein
MTKKHLLTLLLISFFTSFLVACSTTKDKEPQPSDSEIITPRLHQAAHQDKRANFEKIKLATVDSSFTGGTSLEELISLFGEPNQHDPKTAGEVTIDAYTWQFDQVTLTVNLYQNSSIVKTISNFTFARELGLSQKEYQQLQKGMSYEDVKKILTEPDNYSQASSSDHQTLQAIWVSGLKTDTSGANISLVFENNQLTEMSQVGLEE
>NC_009332.1|WP_011888830.1|806218_808483_+|glycogen/starch/alpha-glucan-family-phosphorylase
MTRFTEYVETKLGKSLTQASNEEIYLSLLNFVKEEASHKAKNSAKRKVYYISAEFLIGKLLSNNLINLGIYKDIKEELAAAGKSIAEVEDVELEPSLGNGGLGRLASCFIDSIASLGINGEGVGLNYHCGLFKQVFKHNEQEAEPNYWIEDQSWLVPTNISYDVPFKNFTLKSRLDRIDVLGYKRDTKNYLNLFDIEGVDYGLIKDGISFDKTQIAKNLTLFLYPDDSDKNGELLRIYQQYFMVSNAAQLIIDEAIERGSNLHDLADYAYVQINDTHPSMVIPELIRLLTEKHGFDFDEAVAVVKNMVGYTNHTILAEALEKWPTAYLNEVVPHLVTIIEKLDALVRSEVSDPAVQIIDESGRVHMAHMDIHFATSVNGVAALHTEILKNSELKAFYDLYPEKFNNKTNGITFRRWLEFANQDLADYIKELIGDEYLTDATKLEKLMAFADDKAVHAKLAEIKFDNKLALKRYLKDNKDIELDEHSIIDTQIKRFHEYKRQQMNALYVIHKYLEIKKGNLPKRKITVIFGGKAAPAYIIAQDIIHLILCLSELINNDPEVSPYLNVHLVENYNVTVAEHLIPATDISEQISLASKEASGTGNMKFMLNGALTLGTMDGANVEIAELAGMENIYTFGKDSDTIINLYATASYVAKDYYDNHPAIKAAVNFIISPELLAFGNEERLDRLYKELISKDWFMTLIDLEEYIEVKEKMLADYEDQDLWMTKVVHNIAKAGFFSSDRTIEQYNEDIWHSR
>NC_009332.1|WP_011888833.1|819609_821424_+|glutamine--fructose-6-phosphate-transaminase-(isomerizing)
MCGIVGVVGNRNATDILMQGLEKLEYRGYDSAGIFVANANQTNLIKSVGRIADLRAKIGIDVAGSTGIGHTRWATHGQSTEDNAHPHTSQTGRFVLVHNGVIENYLHIKTEFLAGHDFKGQTDTEIAVHLIGKFVEEDKLSVLEAFKKALSIIEGSYAFALMDSQATDTIYVAKNKSPLLIGLGEGYNMVCSDAMAMIRETSEFMEIHDKELVILTKDKVTVTDYDGKELIRDSYTAELDLSDIGKGTYPFYMLKEIDEQPTVMRQLISTYADETGNVQVDPAIITSIQEADRLYILAAGTSYHAGFATKNILEQLTDTPVELGVASEWGYHMPLLSKKPMFILLSQSGETADSRQVLVKANAMGIPSLTVTNVPGSTLSREATYTMLIHAGPEIAVASTKAYTAQIAALAFLAKAVGEANGKQEALDFNLVHELSLVAQSIEATLSEKDLVAEKVQALLATTRNAFYIGRGNDYYVAMEAALKLKEISYIQCEGFAAGELKHGTISLIEEDTPVIALISSSQLVASHTRGNIQEVAARGAHVLTVVEEGLDREGDDIIVNKVHPFLAPIAMVIPTQLIAYYASLQRGLDVDKPRNLAKAVTVE
>NC_009332.1|WP_011528695.1|821619_821955_+|alkylphosphonate-utilization-protein
MSLPNCLQCQSEYVYEDGLLLICPMCAFEWTPGEEATEEEGLVALDSNGVRLSDGDTITVIKDLKVKGAPKDLKQGTRVKNIRLVEGDHNIDCKIDGFGAMKLKSEFVKKI
>NC_009332.1|WP_002984455.1|822061_822703_+|amino-acid-ABC-transporter-permease
MTYIQQVLPSLLDGALVTLQVFFIVIILSIPLGAILAFLMKVPFKPLQWFLTLYVWMMRGTPLLLQLIFFYYVLPSVGISFDRMPAAILAFTLNYAAYFAEIFRGGIEAIPKGQYEAAKVLKLKPLQTIRYIILPQVFKIVLPSVFNEVINLVKDSSLVYVLGVGDLLLASKTAANRDATLAPMFIAGLIYLLLIGLVTIISKQVEKRFNYYQ
>NC_009332.1|WP_002984457.1|822712_823342_+|amino-acid-ABC-transporter-ATP-binding-protein
MLELKNISKQFGQKTIFDGFNLTVQDGEVLSLVGPSGGGKTTLLRMLAGLESIDSGQVFYNGEDVGIDHLENRNLLGFVFQDFQLFPHLTVLDNLTLSPTITMGKQKADAKEKALDLLARLGLKEHAQVYPYSLSGGQKQRVALARAMMIDPQIIGYDEPTSALDPELRQTVEALIVQNREMGITQIVVTHDLVFAEAISDRIIRVNPK
>NC_009332.1|WP_002984460.1|823357_824194_+|amino-acid-ABC-transporter-substrate-binding-protein
MIIKKRTVAILAIASSFFLVACQATKSLKSGDAWGVYQKQKSITVGFDNTFVPMGYKDESGKCKGFDIDLAKEVFHQYGLKVNFQAINWDMKEAELNNGKIDVIWNGYSITKERQNKVAFTDSYMRNEQIIVVKKRSDIKTISDMKHKVLGAQSASSGYDSLLRTPKLLKDFIKNKDANQYETFTQAFIDLKSDRIDGILIDKVYANYYLAKEGQLENYRMIPTTFENEAFSVGLRKEDKTLQAKINRAFRVLYQNGKFQAISEKWFGDDVATANIKS
>NC_009332.1|WP_011888834.1|824564_825338_+|CAMP-factor-pore-forming-toxin-Cfa
MKPKHLLCLSTVVAGLALFSTMTHSVLADDASNPDTILMNNSQANFQRDALVQKLDEGHQQLEAIKHEAKGTDIEATVNKAIDAVDHMKSSIRFNTETIYDFSSIGARVEALSDAIKAIVFSTTQLTHKVEKAHTDMGFAITKLVIRIIDPFASVDAIKAQVQEIKALEEKVINYPDLQPTDRATIYTKAKLNKAIWNTRLERDKKVLGIKPFDVYNRLNKAITHAVGVQLNPTTTVQQVDDEVIAVQNALETALKS
>NC_009332.1|WP_011888835.1|825707_826943_-|cation-diffusion-facilitator-family-transporter
MTQDPIANLKLARKGPIVSIIVYLLLSVAKLLAGYLLNASSLIADGFNNLSDIVGNVALLIGLHLASQPADANHKFGHWKIEDLSSLVTSFIMFLVGFQVLIHTIKSIFSGQQVDIDPLGAIVGIVSAFVMLGVYVFNKRLSKRVKSSALVAASKDNLADAVTSIGTSIAIIAASLHLPVIDHIAAMIITFFILKTAFDIFMESSFSLSDGFDSRHLKKYEKAILEIPKIVSVKSQRARTYGSNVYLDIVLEMNPDLSVYESHSITEKVEQLLSDQFSIYDIDIHVEPAMIPEEEIFDNVAKKLYRYEKLILSKVPDYDHYIAKSFQLVDANGQTVNYEQFLNQEIYYPSNFNHFQIESISQKTMLVTYQLNGNQRTSIWRRHESWSLLFHQITPIAKRQLHHTHYRIVKM
>NC_009332.1|WP_002984465.1|827062_828385_-|sodium:alanine-symporter-family-protein
MIALVKLIDNLVWGPPLLILLVGTGIYLTSRLGLIQILKLPRAFKLIFSDDEGHGDISSFAALATALAATVGTGNIVGVATAIKSGGPGALFWMWVAAFFGMATKYAEGVLAIKYRTKDANGHISGGPMYYIVNGMGTKWKPLAILFAGSGILVALFGIGTFAQVNSITSSLGHSFGLSPQMVSIVLAIFVAAIIFGGIHSISKVAEKVVPFMAIFYILSSLAVIFSHYQQLLPVIRLVFQSAFTPTAAIGGFAGSLMKDAIQKGIARGVFSNESGLGSAPIAAAAAKTNESVEQGLISMTGTFIDTIIICTLTGLSILVTGQWTGQLEGAPLTQSAFATVFGNLGTFGLTFSLVLFAFTTILGWSYYGERCFEFLFGITHLTYFRIVFILMVGLGGFLKLELIWVLADIVNGLMALPNLIALLALSPVVILETKHYFIK
>NC_009332.1|WP_011284831.1|828913_831232_+|DNA-helicase-PcrA
MNPLLNGMNDRQAQAVQTTEGPLLIMAGAGSGKTRVLTHRIAYLIDEKFVNPWNILAITFTNKAAREMKERALSLNPATKDTLIATFHSMCVRILRREADHIGYNRNFTIVDPGEQRTLMKRILKQLNIDPKKWNERSILGTISNAKNDLLDEKGYEAQAADMYSQIVARCYKAYQEELRRSEALDFDDLIMMTLRLFDANPDVLAYYQQRYQYIHVDEYQDTNHAQYQLIKLLASRFKNICVVGDADQSIYGWRGADMQNILDFEKDYPDAKVVLLEENYRSTKKILQAANDVINNNRNRRPKKLWTQNADGEQLVYYRANDERDEAVFVASTISNMSQELGKNFKDFAVLYRTNAQSRTIEEALLKSNIPYTMVGGTKFYSRKEIRDLIAYLTIVANPADNISFERIVNEPKRGVGPGTLDKLRQFAYESDQSLLEAASNLLMSPLKGKAAQAIMDLANILGQLRQDLDQMSITDLAEALLEKTGYLDSLRLQNTLESQARIENIEEFLSVTKNFDESSASQEEDETGVDRLGRFLNDLALIADTDDSQAEAAEVTLMTLHAAKGLEFPVVFLIGMEEGVFPLSRASEDPDELEEERRLAYVGITRAEEVLFMTNANTRTLFGKSSYNRPTRFLKEISEELLSYKGLARPAQSSFGVRFSTETHTQFGQGMSLSEALQARKAQAQVRQSAQPMQAHTIPSASTSSVLPFGSNSSVEEVTWQIGDIAHHKKWGDGTVLEVSGSGKTMELKIKFPEVGLKKLLASVAPIEKK
>NC_009332.1|WP_002984469.1|831594_831843_+|GlsB/YeaQ/YmgE-family-stress-response-membrane-protein
MGLIWTLIVGALIGVIAGALTKKGGSMGWIANIAAGLVGSSVGQALLGSWGPSLAGMSLIPSVIGAVIVVMITSFVLNKTNN

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Crispr_ID: NC_009332_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_009332_2

1674639-1674784

Orphan

Consensus_repeat	Method
TCATTTTGTAGAAAAAGAAAATTTCTAACTCTTCGCTTTTTCCTACCATAACAT	CRISPRCasFinder

1 spacers

The CRISPR arrays of NC_009332_2

>merge|NC_009332|2|1674639-1674784|CRISPRCasFinder
TCATTTTGTAGAAAAAGAAAATTTCTAACTCTTCGCTTTTTCCTACCATAACATTAAAAGCGCATTGAGCTTGTCAATAATCGCTTCTGGAGTCATTTTGTAGAAAAAGAAAATTTCTAACTCTTCGCTTTTTCCTACCATAACAT

>NC_009332|2|2|1674639-1674784|CRISPRCasFinder
TCATTTTGTAGAAAAAGAAAATTTCTAACTCTTCGCTTTTTCCTACCATAACAT	TAAAAGCGCATTGAGCTTGTCAATAATCGCTTCTGGAG
TCATTTTGTAGAAAAAGAAAATTTCTAACTCTTCGCTTTTTCCTACCATAACAT

Protein	Signature genes	Signature genes Name	Protein_function
NC_009332.1\|WP_002982458.1\|1682252_1682927_-\|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|224059
NC_009332.1\|WP_002982507.1\|1664957_1665158_-\|CsbD-family-protein	unknown	unknown	gnl\|CDD\|225777
NC_009332.1\|WP_011889189.1\|1668993_1672446_-\|C5a-peptidase-ScpA/B	unknown	unknown	gnl\|CDD\|173801
NC_009332.1\|WP_041174199.1\|1659915_1661544_+\|ABC-transporter-substrate-binding-protein	unknown	unknown	gnl\|CDD\|173883
NC_009332.1\|WP_011889187.1\|1665326_1667798_-\|pneumococcal-type-histidine-triad-protein	unknown	unknown	gnl\|CDD\|273578
NC_009332.1\|WP_002991237.1\|1680275_1680929_-\|response-regulator-transcription-factor	unknown	unknown	gnl\|CDD\|223816
NC_009332.1\|WP_011889191.1\|1676831_1677083_-\|hypothetical-protein	unknown	unknown	unknown
NC_009332.1\|WP_011889186.1\|1664250_1664877_+\|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|224049
NC_009332.1\|WP_011889190.1\|1672814_1674293_-\|M-protein	unknown	unknown	gnl\|CDD\|224117
NC_009332.1\|WP_011889188.1\|1667810_1668731_-\|metal-ABC-transporter-substrate-binding-lipoprotein/laminin-binding-adhesin-Lmb	unknown	unknown	gnl\|CDD\|238499
NC_009332.1\|WP_002982442.1\|1684605_1684890_-\|hypothetical-protein	unknown	unknown	unknown
NC_009332.1\|WP_011889194.1\|1685576_1685813_+\|hypothetical-protein	unknown	unknown	unknown
NC_009332.1\|WP_011185011.1\|1661656_1662634_+\|ABC-transporter-permease	unknown	unknown	gnl\|CDD\|223674
NC_009332.1\|WP_011889193.1\|1682913_1684182_-\|efflux-RND-transporter-periplasmic-adaptor-subunit	unknown	unknown	gnl\|CDD\|223914
NC_009332.1\|WP_002991236.1\|1678890_1680279_-\|HAMP-domain-containing-histidine-kinase	unknown	unknown	gnl\|CDD\|223715
NC_009332.1\|WP_002991239.1\|1681022_1682240_-\|ABC-transporter-permease	unknown	unknown	gnl\|CDD\|182528
NC_009332.1\|WP_002982439.1\|1685036_1685333_-\|DUF4298-domain-containing-protein	unknown	unknown	gnl\|CDD\|372919
NC_009332.1\|WP_011889185.1\|1662630_1663452_+\|ABC-transporter-permease	unknown	unknown	gnl\|CDD\|224094
NC_009332.1\|WP_003059481.1\|1663463_1664267_+\|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|223521
NC_009332.1\|WP_011889192.1\|1677160_1678789_-\|CHAP-domain-containing-protein	unknown	unknown	gnl\|CDD\|226451

Protein	Function_ID	Function_description	E-value
NC_009332.1\|WP_002982458.1\|1682252_1682927_-\|ABC-transporter-ATP-binding-protein	gnl\|CDD\|224059	COG1136, SalX, ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms].	8.84255e-116
NC_009332.1\|WP_002982507.1\|1664957_1665158_-\|CsbD-family-protein	gnl\|CDD\|225777	COG3237, COG3237, Uncharacterized protein conserved in bacteria [Function unknown].	7.43573e-06
NC_009332.1\|WP_011889189.1\|1668993_1672446_-\|C5a-peptidase-ScpA/B	gnl\|CDD\|173801	cd07475, Peptidases_S8_C5a_Peptidase, Peptidase S8 family domain in Streptococcal C5a peptidases. Streptococcal C5a peptidase (SCP), is a highly specific protease and adhesin/invasin. The subtilisin-like protease domain is located at the N-terminus and contains a protease-associated domain inserted into a loop. There are three fibronectin type III (Fn) domains at the C-terminus. SCP binds to integrins with the help of Arg-Gly-Asp motifs which are thought to stabilize conformational changes required for substrate binding. Peptidases S8 or Subtilases are a serine endo- and exo-peptidase clan. They have an Asp/His/Ser catalytic triad similar to that found in trypsin-like proteases, but do not share their three-dimensional structure and are not homologous to trypsin. The stability of subtilases may be enhanced by calcium, some members have been shown to bind up to 4 ions via binding sites with different affinity. Some members of this clan contain disulfide bonds. These enzymes can be intra- and extracellular, some function at extreme temperatures and pH values.	2.27926e-76
NC_009332.1\|WP_041174199.1\|1659915_1661544_+\|ABC-transporter-substrate-binding-protein	gnl\|CDD\|173883	cd08518, PBP2_NikA_DppA_OppA_like_19, The substrate-binding component of an uncharacterized ABC-type nickel/dipeptide/oligopeptide-like import system contains the type 2 periplasmic binding fold. This CD represents the substrate-binding domain of an uncharacterized ATP-binding cassette (ABC) type nickel/dipeptide/oligopeptide-like transporter. The oligopeptide-binding protein OppA and the dipeptide-binding protein DppA show significant sequence similarity to NikA, the initial nickel receptor. The DppA binds dipeptides and some tripeptides and is involved in chemotaxis toward dipeptides, whereas the OppA binds peptides of a wide range of lengths (2-35 amino acid residues) and plays a role in recycling of cell wall peptides, which precludes any involvement in chemotaxis. Most of other periplasmic binding proteins are comprised of only two globular subdomains corresponding to domains I and III of the dipeptide/oligopeptide binding proteins. The structural topology of these domains is most similar to that of the type 2 periplasmic binding proteins (PBP2), which are responsible for the uptake of a variety of substrates such as phosphate, sulfate, polysaccharides, lysine/arginine/ornithine, and histidine. The PBP2 bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap. After binding their specific ligand with high affinity, they can interact with a cognate membrane transport complex comprised of two integral membrane domains and two cytoplasmically located ATPase domains. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis. Besides transport proteins, the PBP2 superfamily includes the ligand-binding domains from ionotropic glutamate receptors, LysR-type transcriptional regulators, and unorthodox sensor proteins involved in signal transduction.	0
NC_009332.1\|WP_011889187.1\|1665326_1667798_-\|pneumococcal-type-histidine-triad-protein	gnl\|CDD\|273578	TIGR01363, pneumococcal_histidine_triad_A_protein, streptococcal histidine triad protein. This model represents the N-terminal half of a family of Streptococcal proteins that contain a signal peptide and then up to five repeats of a region that includes a His-X-X-His-X-His (histidine triad) motif. Three repeats are found in the seed alignment. Additional copies in more poorly conserved regions may be detected. Members of this family from Streptococcus pneumoniae are suggested to cleave human C3, and the member PhpA has been shown in vaccine studies to be a protective antigen in mice. [Cellular processes, Pathogenesis].	0
NC_009332.1\|WP_002991237.1\|1680275_1680929_-\|response-regulator-transcription-factor	gnl\|CDD\|223816	COG0745, OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription].	6.27645e-69
NC_009332.1\|WP_011889186.1\|1664250_1664877_+\|ABC-transporter-ATP-binding-protein	gnl\|CDD\|224049	COG1124, DppF, ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism / Inorganic ion transport and metabolism].	5.33186e-91
NC_009332.1\|WP_011889190.1\|1672814_1674293_-\|M-protein	gnl\|CDD\|224117	COG1196, Smc, Chromosome segregation ATPases [Cell division and chromosome partitioning].	4.3463e-12
NC_009332.1\|WP_011889188.1\|1667810_1668731_-\|metal-ABC-transporter-substrate-binding-lipoprotein/laminin-binding-adhesin-Lmb	gnl\|CDD\|238499	cd01017, AdcA, Metal binding protein AdcA. These proteins have been shown to function in the ABC uptake of Zn2+ and Mn2+ and in competence for genetic transformation and adhesion. The AdcA proteins belong to the TroA superfamily of helical backbone metal receptor proteins that share a distinct fold and ligand binding mechanism. They are comprised of two globular subdomains connected by a long alpha helix and they bind their ligand in the cleft between these domains. In addition, many of these proteins have a low complexity region containing metal binding histidine-rich motif (repetitive HDH sequence).	4.72316e-122
NC_009332.1\|WP_011185011.1\|1661656_1662634_+\|ABC-transporter-permease	gnl\|CDD\|223674	COG0601, DppB, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism].	8.91601e-107
NC_009332.1\|WP_011889193.1\|1682913_1684182_-\|efflux-RND-transporter-periplasmic-adaptor-subunit	gnl\|CDD\|223914	COG0845, AcrA, Membrane-fusion protein [Cell envelope biogenesis, outer membrane].	4.03226e-22
NC_009332.1\|WP_002991236.1\|1678890_1680279_-\|HAMP-domain-containing-histidine-kinase	gnl\|CDD\|223715	COG0642, BaeS, Signal transduction histidine kinase [Signal transduction mechanisms].	6.31387e-31
NC_009332.1\|WP_002991239.1\|1681022_1682240_-\|ABC-transporter-permease	gnl\|CDD\|182528	PRK10535, PRK10535, macrolide ABC transporter ATP-binding protein/permease MacB.	9.36566e-52
NC_009332.1\|WP_002982439.1\|1685036_1685333_-\|DUF4298-domain-containing-protein	gnl\|CDD\|372919	pfam14131, DUF4298, Domain of unknown function (DUF4298). This family of proteins is functionally uncharacterized. This family of proteins is found in bacteria and eukaryotes. Proteins in this family are typically between 94 and 105 amino acids in length. There are two completely conserved residues (Y and D) that may be functionally important.	2.929e-24
NC_009332.1\|WP_011889185.1\|1662630_1663452_+\|ABC-transporter-permease	gnl\|CDD\|224094	COG1173, DppC, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism].	1.43494e-69
NC_009332.1\|WP_003059481.1\|1663463_1664267_+\|ABC-transporter-ATP-binding-protein	gnl\|CDD\|223521	COG0444, DppD, ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism / Inorganic ion transport and metabolism].	3.85753e-80
NC_009332.1\|WP_011889192.1\|1677160_1678789_-\|CHAP-domain-containing-protein	gnl\|CDD\|226451	COG3942, COG3942, Surface antigen [General function prediction only].	1.76681e-58

>NC_009332.1|WP_011889190.1|1672814_1674293_-|M-protein
MARENTNKHYSLRKLKKGTASVAVALSVLGAGLVVNTNEVSAAVTRGTINDPQRAKEALDKYELENHDLKTKNEGLKTENEGLKTENEGLKTENEGLKTEKKEHEAENDKLKQQRDTLSTQKETLEREVQNTQYNNETLKIKNGDLTKELNKTRQELANKQQESKENEKALNELLEKTVKDKIAKEQENKETIGTLKKILDETVKDKIAKEQENKETIGTLKKILDETVKDKLAKEQKSKQNIGALKQELAKKDEANKISDASRKGLRRDLDASREAKKQLEAEHQKLEEQNKISEASRKGLRRDLDASREAKKQLEAEHQKLEEQNKISEASRKGLRRDLDASREAKKQVEKALEEANSKLAALEKLNKELEESKKLTEKEKAELQAKLEAEAKALKEQLAKQAEELAKLRAGKASDSQTPDTKPGNKAVPGKGQAPQAGTKPNQNKAPMKETKRQLPSTGETANPFFTAAALTVMATAGVAAVVKRKEEN
>NC_009332.1|WP_011889189.1|1668993_1672446_-|C5a-peptidase-ScpA/B
MRKKQKLPFDKLAIALMSTSILLNAQSDIKANTVTEDTPVTEQAVETPQPTAVSEEAPSSKKTKTPQTPDDAEETVADEANDLAPQAPAKTADTPATSKATIRDLNDPSQVKTLQEKAGKGAGTVVAVIDAGFDKNHEAWRLTDKTKARYQSKEDLEKAKKEHGITYGEWVNDKVAYYHDYSKDGKTAVDQEHGTHVSGILSGNAPSETKEPYRLEGAMPEAQLLLMRVEIVNGLADYARNYAQAIRDAVNLGAKVINMSFGNAALAYANLPDETKKAFDYAKSKGVSIVTSAGNDSSFGGKTRLPLADHPDYGVVGTPAAADSTLTVASYSPDKQLTETATVKTADKQDKEMPVLSTNRFEPNKAYDYAYANRGTKEDDFKDVKGKIALIERGDIDFKDKIANAKKAGAVGVLIYDNQDKGFPIELPNVDQMPAAFISRKDGLLLKDNPQKTITFNATPKVLPTASGTKLSRFSSWGLTADGNIKPDIAAPGQDILSSVANNKYAKLSGTSMSAPLVAGIMGLLQKQYETQYPDMTPSERLDLAKKVLMSSATALYDEDEKAYFSPRQQGAGAVDAKKASAATMYVTDKDNTSSKVHLNNVSDTFEVTVTVHNKSDKPQELYYQATVQTDKVDGKHFALAPKALYETSWQKITIPANSSKQVTVPIDASRFSKDLLAQMKNGYFLEGFVRFKQDPKKEELMSIPYIGFRGDFGNLSALEKPIYDSKDGSSYYHEANSDAKDQLDGDGLQFYALKNNFTALTTESNPWTIIKAVKEGVENIEDIESSEITETIFAGTFAKQDDDSHYYIHRHANGKPYAAISPNGDGNRDYVQFQGTFLRNAKNLVAEVLDKEGNVVWTSEVTEQVVKNYNNDLASTLGSTRFEKTRWDGKDKDGKVVANGTYTYRVRYTPISSGAKEQHTDFDVIVDNTTPEVATSATFSTEDRRLTLASKPKTSQPVYRERIAYTYMDEDLPTTEYISPNEDGTFTLPEEAETMEGATVPLKMSDFTYVVEDMAGNITYTPVTKLLEGHSNKPEQDGSDQVPDKKPETNPEQDGSDQAPDKKPETKPEQDGSGQTPGKTPQKGQPSRTLEKRSSKRALATKASARDQLPTTNDKDTNRLHLLKLVMTTFFFGLVAHIFKTKRQKETKK
>NC_009332.1|WP_011889188.1|1667810_1668731_-|metal-ABC-transporter-substrate-binding-lipoprotein/laminin-binding-adhesin-Lmb
MKKGFFLMAIVVSLVMIAGCDKSANPKQPTQGMSVVTSFYPMYAMTKEVSGDLNDVRMIQSGAGIHSFEPSVNDVAAIYDADLFVYHSHTLEAWARDLDPNLKKSKVDVFEASKPLTLDRVKGLEDMEVTQGIDPATLYDPHTWTDPVLAGEEAVNIAKELGRLDPKHKDSYTKKAKAFKKEAEQLTEEYTQKFKKVRSKTFVTQHTAFSYLAKRFGLKQLGISGISPEQEPSPRQLKEIQDFVKEYNVKTIFAEDNVNPKIAHAIAKSTGAKVKTLSPLEAAPSGNKTYLENLRANLEVLYQQLK
>NC_009332.1|WP_011889187.1|1665326_1667798_-|pneumococcal-type-histidine-triad-protein
MKKTYGYIGSVAAILLATHIGSYQLGKHHMGPVTKDNQIAYIDDSKGKAKAPKTNKTMDQISAEEGISAEQIVVKITDQGYVTSHGDHYHFYNGKVPYDAIISEELLMTDPNYHFKQSDVINEILDGYVIKVNGNYYVYLKPGSKRKNIRTKQQIAEQVAKGTKEAKEKGLAQVAHLSKEEVAAVNEAKRQGRYTTDDGYIFSPTDIIDDLGDAYLVPHGNHYHYIPKKDLSPSELAAAQAYWSQKQGRGARPSDYRPTPAPGRRKAPIPDVTPNPGQGHQPDNGGYHPAPPRPNDASQNKHQRDEFKGKTFKELLDQLHRLDLKYRHVEEDGLIFEPTQVIKSNAFGYVVPHGDHYHIIPRSQLSPLEMELADRYLAGQTEDNDSGSEHSKPSDKEVTHTFLGHRIKAYGKGLDGKPYDTSDAYVFSKESIHSVDKSGVTAKHGDHFHYIGFGELEQYELDEVANWVKAKGQADELAAALDQEQGKEKPLFDTKKVSRKVTKDGKVGYIMPKDGKDYFYARDQLDLTQIAFAEQELMLKDKKHYRYDIVDTGIEPRLAVDVSSLPMHAGNATYDTGSSFVIPHIDHIHVVPYSWLTRDQIATIKYVMQHPEVRPDVWSKPGHEESGSVIPNVTPLDKRAGMPNWQIIHSAEEVQKALAEGRFATPDGYIFDPRDVLAKETFVWKDGSFSIPRADGSSLRTINKSDLSQAEWQQAQELLAKKNAGDATDTDKPKEKQQADKSNENQQPSEASKEEEKESDDFIDSLPDYGLDRATLEDHINQLAQKANIDPKYLIFQPEGVQFYNKNGELVTYDIKTLQQINP
>NC_009332.1|WP_002982507.1|1664957_1665158_-|CsbD-family-protein
MSEEKLKSKIEQASGGLKEGAGKLTGDKELEAKGFVEKTIAKGKELADDAKEAVEGAVDAVKEKLK
>NC_009332.1|WP_011889186.1|1664250_1664877_+|ABC-transporter-ATP-binding-protein
MTLEAKKLGFYHKKDQWLFKEIDLEVAPGQILGIFGQSGCGKTSLSRVLAGFLQPKYGEVLVDGSHLPNKAFRPVQLIQQHPEQTMNPLWPMKKSLEEAYYPSQDLRDAFGIQEKWLKRRPSELSGGELQRFSIVRSLHPETKYLIADEMTTMLDSITQASVWKSLLEIVKDRNLGLIVISHDFDMLEKLCDACYMIEENRTQLFKHT
>NC_009332.1|WP_003059481.1|1663463_1664267_+|ABC-transporter-ATP-binding-protein
MTETLLSIKDLSITFTQYGRFLKPFQSTPIQALNLEVKKGELLAIIGASGSGKSLLAHAIMDILPKNAAVTGDMIYRGQSLTSKRIKQLRGKEMTLIPQSVNYLDPSMKVKHQVRLGISENAKATQEGLFQQFGLKESDGDLYPFQLSGGMLRRVLFTTCISDTVSLIIADEPTPGLHPDALQMVLDQLRSFADKGISVIFITHDIVAASQIADRITIFKEGKAIETAPASFFSGGGEQLQTEFARRLWRTLPQQDFLKGVTHDLRG
>NC_009332.1|WP_011889185.1|1662630_1663452_+|ABC-transporter-permease
MILKRRTMVLWQLGIAISLILSILALNLYFYRTPLETNAALRNLAPSLNHLFGTDGLGRDMFVRTIKGLYFSLQVGLLGALMGVFLATVFGVLAGLGNSLIDKIIAWLVDLFIGMPHLIFMILISFVVGKGAQGVIIATAVTHWPSLARLIRNEVYDLKNKAFVQLSKSMGKTPYYIVRHHILPLIASQIFIGFILLFPHVILHEASMTFLGFGLSAEQPSVGIILSEAAKHISLGNWWLVVFPGLYLILVVNAFDTIGESLKKLFYPQTDHF
>NC_009332.1|WP_011185011.1|1661656_1662634_+|ABC-transporter-permease
MKRTTIIIIWKIIRCITLIFGVSVLTFVLLKQSPVDPVMASVNYDTSLTPAQYKAIAHHYGLDKPALVQYFIWLKNVIQGHLGTSLVYRQPVSDIIRSRAGASFILMGLSWILSGLIGFILGTLSAFHQGKLLDRVVRWFSYLQISVPTFWIGLIFLLIFSVQLGWFPIGISSPIGTLSQDITLADRIKHLMLPVFTLSILGIANVTLHTRTKMMSVLSSEYVLFARARGETQWQIFKNHCLRNAIVPAITLHFSYFGELFGGSVLAEQVFSYPGLGSTLTEAGLKSDTPLLLAIVMIGTLFVFAGNLIADILNSIINPQLRRKV
>NC_009332.1|WP_041174199.1|1659915_1661544_+|ABC-transporter-substrate-binding-protein
MSKYLKYFSIITLFLTGLILVACQQQKPQTKERQRKQRPKDELVVSMGAKLPHEFDPKDRYGVHNEGNITHSTLLKRSPELDIKGELAKTYHLSEDGLTWSFDLHDDFKFSNGEPVTADDVKFTYDMLKADGKAWDLTFIKNVEVVGKNQINIHLTEAHSTFTAQLTEIPIVPKKHYNDKYKSNPIGSGPYMVKEYKAGEQAIFVRNPYWHGKKPYFKKWTWVLLDENTALAALESGDVDMIYATPELASKKVKGTRLLDIPSNDVRGLSLPYVKKGVITDSPDGYPVGNDVTSDPAIRKALTIGLNRQKVLDTVLNGYGKPAYSIIDKTPFWNPKTAIKDNKVAKAKQLLTKAGWKEQADGSRKKGDLDAAFDLYYPTNDQLRANLAVEVAEQAKALGITIKLKASNWDEMATKSHDSALLYAGGRHHAQQFYESHHPSLAGKGWTNITFYNNPTVTKYLDKAMTSSDLDKANEYWKLAQWDGKTGASTLGDLPNVWLVSLNHTYIGDKRINVGKQGVHSHGHDWSLLTNIAEWTWDESTK
>NC_009332.1|WP_011889191.1|1676831_1677083_-|hypothetical-protein
MTKKVTTPSQKTKKRVRNGYLLKLGTACLLLSILSYGIGLLGQPSMENTFMGIASVAMLGSVCFFIIFALNRIFDALEDNLRD
>NC_009332.1|WP_011889192.1|1677160_1678789_-|CHAP-domain-containing-protein
MKKRKLLAVTLLSTILLNSAVPLVVADTSLRNSTSSTDQPTTADTDTDDESETPKKDKKSKETASQHDTQKDHKPSHNHPTPPSNDTKQTDQASSEATDKPNKDKNNTNQPNSSDQSTPSPKDQSSQKESQNKDGRPTPSPDQQKDQTPDKTPEKSADKTPEKGPEKATEKTPEPNRDAPKPNQPPLAAAAPVFAPWRESDKDLSKLKPSSRSSAAYVRHWTGDSAYTHNLLSRRYGITAEQLDGFLNSLGIHYDKERLNGKRLLEWEKLTGLDVRAIVAIAMAESSLGTQGVAKEKEANMFGYGAFDFNPNNAKKYSDEVAIRHMVEDTIIANKNQTFERQDLKAKKWSLGQLDTLIDGGVYFTDTSGSGQRRADIMTKLDQWIDDHGSTPEIPEHLKITSGTQFSEVPVGYKRSQPQNVLTYKSETYSFGQCTWYAYNRVKELGYQVDRYMGNGGDWQRKPGFVTTHKPKVGYVVSFAPGQAGADATYGHVAVVEQIKEDGSILISESNVMGLGTISYRTFTAEQARLLTYVVGDKLPRP
>NC_009332.1|WP_002991236.1|1678890_1680279_-|HAMP-domain-containing-histidine-kinase
MRLIKKTFLVINGLIIVVVTSILLVLYFAMPIYYTKVKDKEVKREFDQTSKQIKGKTVTEIRDILTKKINKDNIWYSLVDSDNQLLYPSLQLLDGVSESKDSQNVNIVTTFDNSYSNVKVMSQKVTLRDGKKMTLLGQSSLQPVTDASKVLLDLYPSLLIFSVTVGSIVAYLYSRTSSRRILSMSQTAKKMVNLEPNLTCTIHGKDEIAMLASDINRLYASLSTSIKSLQKEYEKASDSEREKSEFLRMTSHELKTPITSVIGMIDGMLYNVGDFADRDKYLRKCRDVLEGQAQLVQSILSLSKIETLASQNQELFSLKSSLEEEMEVFLVLSELKHLKVTINLEEQFVKANKVYLLKAIKNIIDNAFHYTKPGGQVMIQLKDNQLVIKNEAETLLTQQQMKQLFQPFYRPDYSRNRKDGGTGLGLFITHQILDQHHLAYRFVVLDQRWMVFTIDFPSHHDD
>NC_009332.1|WP_002991237.1|1680275_1680929_-|response-regulator-transcription-factor
MFKILVVEDDDTISQVICEFLKANNYDPDCVFDGQAALDKWQTTSYDLIILDIMLPSLSGLEVLKTIRKTSDVPIIMLTALDDEYTQLVSFNHLISDYVTKPFSPLILIKRIENVLRVSTPDEKRQIGDLLVDETEHSVYWQGTLVKLTKKEYDIIDYLAKRHQKIVTRDQLMDDIWGYSELDTRVLDNHIKNLRKKMTGIPLKTITGMGYLLGERE
>NC_009332.1|WP_002991239.1|1681022_1682240_-|ABC-transporter-permease
MEDIIAALGSILSHKMRSILTMLGIIIGIGAIIAIFSIIEGNTENTKRQLIGGSNNTINIVFNKKSSIDPKFPDKSNAKKPDYLPFMAEEELSKIQQVKGVKNALISYGIDDKVYHLGQKSSAKISAITKNVAEVRRMTFIKGSDFSDKDFIDQKQVIYLEKSLYESLFPKDDGLGKFVEVMGNPFRVIGVFESKEQSGLTSGTEKIAYIPLHQWYNINGVVDATPEITIQTYRADDLKPVAKRVSDMLNQTIPKSDYMFGVMNLKEFERQLDNLNKSNFVLLAGIASISLIVGGIGVMNIMLVSVTERTREIGIKKALGARRKLILKQFLIEAVILTLLGGVIGVISGMVSGLIITRSLEYPYILSLFSVVLSLAFCCIIGIVFGLLPAIKASKLDPIEALRFE
>NC_009332.1|WP_002982458.1|1682252_1682927_-|ABC-transporter-ATP-binding-protein
MLNLKDIRKSYHLGTEEFAILKGIDLEVNEGDFLAIMGPSGSGKSTLMNIIGCLDKPGSGSYAIEGRDVSSLSDNELADLRNQKIGFVFQNFNLMPKLTACQNVELPLTYMNVPKKERRKRALEMLKLVGLEERSEFKPMELSGGQKQRVAIARALVTNPSFILGDEPTGALDTKTSVQIMDLFKQFNDNGKTIIIITHEPEVAALCKKTVILRDGNIEHSDIE
>NC_009332.1|WP_011889193.1|1682913_1684182_-|efflux-RND-transporter-periplasmic-adaptor-subunit
MFQLRKKMTRKQLALLSAGVLTCVVGGSYLIMNHQQQEVVSSVNKVKALTIKEAMEQGKDISLTLAGEVTANNSSKVKIDSSKGEVKEVFVKKGDVVKVGQPLFSYETSQRLTAQSSEFDVQTKANQLQVAKTNAALKWETYNRKVNEINTLKSRYNTAPDESLLEQIRSAEDSVSQALSDAKTADSDVKTAQIELDKANATATMEKGKLEYDTVKSDTAGTIVSLNTDLPNQSKSKKENETFMEIIDKSKMLVKGNISEFDRDKLKIDQKVEVIDRKDNSKKWTGKVTQVGNLKAEEKGQGQGQGGNDQQDNPNQAKFPYVIELDQSDKQPLIGSHTYVNVLNNVPEAGKIVLKETFTMAENGKTYVWKVDKNKVKKQEIKTKPFSKGYVEVTSGLTMQDKIAQPLPGMKDGMEVGSIVKP
>NC_009332.1|WP_002982442.1|1684605_1684890_-|hypothetical-protein
MKFKKVLVIPALALAATCFLTACGTKKDSKKEEVKEIKMSDIKDDAVSKKTKVVDGEEVTEYTTKDGNVIQIPAGNEEGMESKDAGGSGAPAKN
>NC_009332.1|WP_002982439.1|1685036_1685333_-|DUF4298-domain-containing-protein
MTKQDQLIVEKMEQTYEAFSPKLANLIEALDAFKEHYEEYATLRNFYSSDEWFRLANQPWDDIPCGVLSEDLLFDMIGDHNQLLADILDLAPIMYKHM
>NC_009332.1|WP_011889194.1|1685576_1685813_+|hypothetical-protein
MTHRFFLTPLSTLWRRLRPKRYSKKVLADEPTSYQPPIAHGPCDDTHQLLEDKSLSDDYLIATSAMRHLWYWGYSQIG

You can click texts colored in the table to view more detailed information

Click the colored protein region to show detailed information

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

490302 : 555874

Temperate_phage(47.17%)

tRNA,holin,tail,terminase,portal,capsid

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_002988958.1\|490302_491238_+\|tRNA	methionyl-tRNA formyltransferase	M4QRX9	Synechococcus_phage	6.0e-05	38.5
WP_011184816.1\|491227_492550_+	16S rRNA (cytosine(967)-C(5))-methyltransferase RsmB	NA	NA	NA	NA
WP_002983660.1\|492587_493328_+	Stp1/IreP family PP2C-type Ser/Thr phosphatase	NA	NA	NA	NA
WP_011888669.1\|493324_495223_+	Stk1 family PASTA domain-containing Ser/Thr kinase	B5LWE2	Feldmannia_species_virus	3.2e-21	30.3
WP_011888670.1\|495345_496038_+	cell wall-active antibiotics response protein	NA	NA	NA	NA
WP_002991890.1\|496034_497039_+	sensor histidine kinase	NA	NA	NA	NA
WP_011888671.1\|497031_497673_+	response regulator transcription factor	NA	NA	NA	NA
WP_011888672.1\|497709_499110_+	bifunctional Cof-type HAD-IIB family hydrolase/peptidylprolyl isomerase	A0A1V0S9I2	Catovirus	5.4e-26	43.5
WP_002991882.1\|499109_499487_+	S1 RNA-binding domain-containing protein	NA	NA	NA	NA
WP_011888673.1\|499504_500446_-	cysteine synthase A	A0A1X9I5F1	Streptococcus_phage	1.7e-129	77.2
WP_009880468.1\|500573_501206_-	YigZ family protein	A0A1X9I5T8	Streptococcus_phage	3.2e-63	54.3
WP_011184811.1\|501261_502587_+	DEAD/DEAH box helicase	A0A1X9I5S6	Streptococcus_phage	3.1e-116	50.8
WP_002983685.1\|502558_503224_+	ComF family protein	NA	NA	NA	NA
WP_002988974.1\|503303_503852_+	ribosome-associated translation inhibitor RaiA	NA	NA	NA	NA
WP_002983693.1\|511629_512163_-	DUF402 domain-containing protein	NA	NA	NA	NA
WP_011888675.1\|512242_513019_-	recombination regulator RecX	NA	NA	NA	NA
WP_011888677.1\|514515_515937_-	DUF4041 domain-containing protein	M1PLF9	Streptococcus_phage	1.9e-140	75.2
WP_041174188.1\|515951_516338_-	ImmA/IrrE family metallo-endopeptidase	A0A1P8VVK5	Streptococcus_phage	1.2e-52	76.8
WP_011888679.1\|516321_516663_-	helix-turn-helix transcriptional regulator	J7KJZ4	Streptococcus_phage	1.2e-48	85.8
WP_014635614.1\|516860_517073_+	DNA-binding protein	J7KBP9	Streptococcus_phage	9.2e-31	95.7
WP_011888681.1\|517100_517820_+	phage antirepressor KilAC domain-containing protein	M1Q1T4	Streptococcus_phage	7.4e-88	70.3
WP_011284879.1\|517917_518157_-	hypothetical protein	NA	NA	NA	NA
WP_011054585.1\|518323_518509_+	helix-turn-helix transcriptional regulator	A0A1X9I6I3	Streptococcus_phage	3.3e-16	72.1
WP_011888682.1\|518579_518831_+	hypothetical protein	A0A1P8VVV6	Streptococcus_phage	2.6e-40	97.6
WP_011017881.1\|518861_518999_+	hypothetical protein	A0A097PAR2	Streptococcus_pyogenes_phage	3.4e-18	100.0
WP_011888683.1\|519092_519809_+	replication initiator protein A	A0A097PBE7	Streptococcus_pyogenes_phage	2.9e-129	93.7
WP_011888684.1\|519795_520578_+	ATP-binding protein	A0A097PAQ0	Streptococcus_pyogenes_phage	1.0e-143	97.3
WP_011285579.1\|520718_521072_+	hypothetical protein	A0A097PAU3	Streptococcus_pyogenes_phage	2.8e-16	54.0
WP_011018143.1\|521052_521307_+	hypothetical protein	Q938N0	Temperate_phage	3.7e-42	98.8
WP_011018142.1\|521328_521811_+	siphovirus Gp157 family protein	Q938M9	Temperate_phage	8.2e-51	100.0
WP_011106686.1\|522908_523112_+	hypothetical protein	Q938M6	Temperate_phage	4.7e-32	100.0
WP_011285574.1\|523111_523552_+	RusA family crossover junction endodeoxyribonuclease	A0A097PAS0	Streptococcus_pyogenes_phage	4.5e-80	97.9
WP_011284873.1\|523548_523905_+	hypothetical protein	A0A097PAU4	Streptococcus_pyogenes_phage	2.9e-61	100.0
WP_002995955.1\|524146_524383_+	DUF3310 domain-containing protein	A0A097PAQ7	Streptococcus_pyogenes_phage	2.4e-40	100.0
WP_002995952.1\|524379_524550_+	hypothetical protein	Q938M0	Temperate_phage	7.9e-09	87.1
WP_011284869.1\|524546_524831_+	hypothetical protein	A0A097PAV1	Streptococcus_pyogenes_phage	2.6e-36	86.2
WP_011888685.1\|524832_525465_+	SAM-dependent DNA methyltransferase	L0P368	Streptococcus_phage	5.1e-85	68.6
WP_011888686.1\|525469_525949_+	DUF1642 domain-containing protein	A0A141E0J6	Streptococcus_phage	6.5e-24	41.9
WP_002987493.1\|525945_526116_+	hypothetical protein	A0A097PAS8	Streptococcus_pyogenes_phage	2.9e-27	100.0
WP_011888687.1\|526399_526834_+	ArpU family transcriptional regulator	J7KDQ1	Streptococcus_phage	1.7e-71	94.4
WP_010922073.1\|528977_529454_+	hypothetical protein	Q938L4	Temperate_phage	4.9e-48	68.4
WP_010922074.1\|529536_530748_+\|terminase	PBSX family phage terminase large subunit	Q938L3	Temperate_phage	3.7e-225	99.7
WP_010922075.1\|530761_532264_+\|portal	phage portal protein	Q938L2	Temperate_phage	5.9e-281	99.6
WP_010922077.1\|533761_533989_+	hypothetical protein	NA	NA	NA	NA
WP_011888689.1\|534075_534342_+	hypothetical protein	Q938K9	Temperate_phage	6.4e-37	95.5
WP_011888690.1\|534467_535082_+	hypothetical protein	Q938K8	Temperate_phage	3.8e-93	93.1
WP_011888691.1\|535085_535904_+\|capsid	N4-gp56 family major capsid protein	Q79S85	Temperate_phage	2.0e-145	99.6
WP_011888692.1\|535957_536374_+	hypothetical protein	Q938K7	Temperate_phage	9.6e-56	98.2
WP_011888693.1\|536363_536696_+	hypothetical protein	Q79S86	Temperate_phage	6.2e-58	99.1
WP_010922083.1\|536695_537052_+	hypothetical protein	Q79S88	Temperate_phage	4.5e-62	100.0
WP_011888694.1\|537048_537447_+\|capsid	phage capsid protein	Q79S87	Temperate_phage	6.5e-70	98.5
WP_011018120.1\|537446_537908_+	hypothetical protein	Q938K6	Temperate_phage	1.9e-60	78.8
WP_011888695.1\|537951_538386_+	hypothetical protein	Q938K5	Temperate_phage	4.2e-70	97.9
WP_011888696.1\|538389_538971_+	hypothetical protein	Q938K4	Temperate_phage	1.0e-100	94.3
WP_011888697.1\|542211_542928_+\|tail	phage tail family protein	Q938K2	Temperate_phage	1.2e-135	99.2
WP_011888698.1\|542924_545069_+\|tail	phage tail protein	Q938K1	Temperate_phage	0.0e+00	95.1
WP_011017589.1\|545065_546076_+	hyaluronoglucosaminidase	Q938K0	Temperate_phage	7.8e-136	75.8
WP_002983467.1\|547985_548417_+	DUF1617 family protein	Q938J8	Temperate_phage	1.3e-63	89.5
WP_011888699.1\|548419_549052_+	hypothetical protein	Q938J7	Temperate_phage	3.2e-42	48.6
WP_011184730.1\|549061_549517_+\|holin	phage holin family protein	A0A0M4R3G6	Streptococcus_phage	2.3e-63	81.5
WP_011888700.1\|549628_550834_+	glucosaminidase domain-containing protein	Q938J4	Temperate_phage	1.8e-203	83.5
WP_011017840.1\|550973_551498_+	DUF4065 domain-containing protein	Q938J3	Temperate_phage	4.0e-99	100.0
WP_011888701.1\|551485_552352_+	DUF334 domain-containing protein	Q938J2	Temperate_phage	1.1e-133	99.7
WP_011888702.1\|552401_552836_-	hypothetical protein	NA	NA	NA	NA
WP_011285611.1\|553107_553908_-	streptodornase Sda3	NA	NA	NA	NA
WP_011184907.1\|554145_554328_+	hypothetical protein	A3F673	Streptococcus_phage	4.4e-21	83.3
WP_011888703.1\|554518_555874_+	23S rRNA (uracil(1939)-C(5))-methyltransferase RlmD	A0A2K5B251	Erysipelothrix_phage	5.1e-74	33.2

DBSCAN-SWA_2

631030 : 693862

Streptococcus_phage(56.45%)

transposase,tRNA,tail,protease,terminase,portal,integrase,capsid

attL 654418:654437|attR 690403:690422

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_011888738.1\|631030_633832_+\|tRNA	isoleucine--tRNA ligase	H2EEZ0	Moumouvirus	2.1e-69	26.7
WP_002983878.1\|634095_634398_-	DUF1827 family protein	NA	NA	NA	NA
WP_002989103.1\|634448_634904_-	NUDIX hydrolase	NA	NA	NA	NA
WP_011888739.1\|635031_637314_-\|protease	ATP-dependent Clp protease ATP-binding subunit	A0A2C9CYX3	Yersinia_phage	8.3e-125	39.7
WP_002983885.1\|637611_637842_+	YkuJ family protein	NA	NA	NA	NA
WP_002983887.1\|637968_638655_+	amino acid ABC transporter permease	NA	NA	NA	NA
WP_011888740.1\|638654_639389_+	amino acid ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	1.6e-34	38.8
WP_011888741.1\|639537_640947_+	deoxyribodipyrimidine photo-lyase	A0A1V0SGL1	Hokovirus	2.6e-60	33.1
WP_011888742.1\|640956_641955_-\|transposase	IS30-like element IS1239 family transposase	H7BW61	unidentified_phage	1.0e-31	34.6
WP_011888743.1\|642210_643905_+	phospho-sugar mutase	A0A1X9I671	Streptococcus_phage	2.7e-128	42.4
WP_002989114.1\|644112_644967_+	bifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase	A0A249XZQ2	Enterococcus_phage	4.4e-39	39.4
WP_011017997.1\|645119_646460_+	exodeoxyribonuclease VII large subunit	A0A1V0SIT1	Klosneuvirus	8.2e-40	30.9
WP_002983901.1\|646437_646653_+	exodeoxyribonuclease VII small subunit	NA	NA	NA	NA
WP_011888744.1\|646652_647525_+	polyprenyl synthetase family protein	NA	NA	NA	NA
WP_011017996.1\|647517_648345_+	TlyA family RNA methyltransferase	NA	NA	NA	NA
WP_002983907.1\|648331_648802_+	arginine repressor	NA	NA	NA	NA
WP_011017995.1\|648822_650484_+	DNA repair protein RecN	NA	NA	NA	NA
WP_011888745.1\|650655_651594_+	LPXTG cell wall anchor domain-containing protein	NA	NA	NA	NA
WP_002983913.1\|651809_652661_+	DegV family protein	A0A0N9SI50	Staphylococcus_phage	5.4e-13	35.7
WP_011888746.1\|652653_653496_+	SGNH/GDSL hydrolase family protein	NA	NA	NA	NA
WP_002989129.1\|653473_654061_+	YpmS family protein	NA	NA	NA	NA
WP_002983920.1\|654159_654435_+	HU family DNA-binding protein	A7KV42	Bacillus_phage	2.6e-25	73.0
654418:654437	attL	NA	NA	NA	NA
WP_003051793.1\|654524_655667_-\|integrase	site-specific integrase	M1NRJ9	Streptococcus_phage	2.4e-173	77.4
WP_011285632.1\|655790_656057_-	DUF4177 domain-containing protein	NA	NA	NA	NA
WP_011888747.1\|656068_656455_-	hypothetical protein	M1PFJ2	Streptococcus_phage	3.3e-34	55.5
WP_011888748.1\|656457_656808_-	helix-turn-helix transcriptional regulator	C5J980	Streptococcus_phage	1.1e-33	62.6
WP_011888749.1\|657115_657331_+	hypothetical protein	M1Q1B4	Streptococcus_phage	4.1e-26	81.2
WP_011888751.1\|657840_658026_+	helix-turn-helix transcriptional regulator	J7KH19	Streptococcus_phage	8.1e-23	85.2
WP_002990080.1\|658104_658416_+	hypothetical protein	A0A1S5SA25	Streptococcus_phage	4.1e-43	78.4
WP_011888752.1\|658417_658603_+	hypothetical protein	Q938N3	Temperate_phage	1.8e-22	91.8
WP_002985388.1\|659120_659507_+	DnaD domain-containing protein	Q938N2	Temperate_phage	2.8e-25	55.0
WP_002985387.1\|659487_659721_+	hypothetical protein	Q938N1	Temperate_phage	6.1e-36	94.8
WP_011017992.1\|659717_659858_+	hypothetical protein	NA	NA	NA	NA
WP_011017565.1\|659866_660073_+	hypothetical protein	NA	NA	NA	NA
WP_011888754.1\|660128_660458_+	hypothetical protein	J7KGX3	Streptococcus_phage	3.8e-47	87.2
WP_011888755.1\|660460_661237_+	phage recombination protein Bet	A0A1S5SFP4	Streptococcus_phage	1.3e-114	81.5
WP_011888756.1\|661246_662275_+	DUF1351 domain-containing protein	E8ZD61	Streptococcus_phage	9.5e-121	65.9
WP_011888757.1\|662470_662812_+	hypothetical protein	M1NS23	Streptococcus_phage	3.1e-12	38.7
WP_011888758.1\|662808_663321_+	hypothetical protein	Q708P9	Streptococcus_phage	2.1e-65	76.8
WP_011888759.1\|663520_663763_+	hypothetical protein	A7J287	Streptococcus_phage	1.6e-23	73.8
WP_011888760.1\|663752_664517_+	site-specific DNA-methyltransferase	Q9MCL7	Streptococcus_virus	1.8e-129	89.4
WP_011888761.1\|664564_664858_+	hypothetical protein	A0A097PAR1	Streptococcus_pyogenes_phage	3.0e-48	97.9
WP_011888762.1\|664854_665376_+	DUF1642 domain-containing protein	Q938L9	Temperate_phage	1.5e-69	77.5
WP_002987493.1\|665372_665543_+	hypothetical protein	A0A097PAS8	Streptococcus_pyogenes_phage	2.9e-27	100.0
WP_011888763.1\|665809_666229_+	DUF1492 domain-containing protein	A0A1X9I5B5	Streptococcus_phage	1.9e-56	79.9
WP_010922469.1\|666337_666682_+	HNH endonuclease	M1Q0W7	Streptococcus_phage	5.5e-41	68.5
WP_002994106.1\|666830_667187_+	hypothetical protein	M1PRL3	Streptococcus_phage	2.4e-07	57.8
WP_011017979.1\|667183_668452_+\|portal	phage portal protein	A0A1X9I693	Streptococcus_phage	2.4e-190	76.2
WP_011017978.1\|668444_669938_+	hypothetical protein	M1Q184	Streptococcus_phage	3.7e-89	55.6
WP_002994100.1\|669943_670168_+	hypothetical protein	NA	NA	NA	NA
WP_011054687.1\|670244_670397_+	hypothetical protein	NA	NA	NA	NA
WP_002986828.1\|670389_670656_+	hypothetical protein	Q938K9	Temperate_phage	6.4e-37	95.5
WP_011888764.1\|670657_670894_+	hypothetical protein	M1IRA5	Streptococcus_phage	1.2e-31	80.3
WP_011888765.1\|670975_672391_+\|terminase	terminase	A0A0B5A091	Streptococcus_phage	8.2e-216	75.1
WP_011888766.1\|672461_672923_+	DUF4355 domain-containing protein	M1Q1L0	Streptococcus_phage	1.7e-37	52.6
WP_011888767.1\|672947_673859_+\|capsid	phage major capsid protein	M1PFL0	Streptococcus_phage	1.4e-112	66.7
WP_010922460.1\|673858_674059_+	hypothetical protein	NA	NA	NA	NA
WP_011054682.1\|674068_674491_+	hypothetical protein	A0A0B5A2F6	Streptococcus_phage	8.2e-47	67.2
WP_011054681.1\|674450_674789_+	hypothetical protein	A0A0B5A086	Streptococcus_phage	8.1e-45	75.0
WP_000032787.1\|674781_675018_+	hypothetical protein	A0A1P8BMT2	Lactococcus_phage	2.5e-21	66.7
WP_000573598.1\|675018_675354_+	hypothetical protein	A0A1P8BMR5	Lactococcus_phage	9.8e-35	64.9
WP_011888768.1\|675365_675944_+	hypothetical protein	A0A1X9I5X2	Streptococcus_phage	2.9e-58	62.9
WP_010922455.1\|675954_676218_+	hypothetical protein	A0A0B5A2F3	Streptococcus_phage	1.0e-18	55.8
WP_011528785.1\|676232_676604_+	DUF5361 domain-containing protein	M1PL84	Streptococcus_phage	1.2e-33	59.2
WP_011888769.1\|676603_678961_+	hypothetical protein	M1NRG5	Streptococcus_phage	2.5e-145	50.9
WP_011888770.1\|678957_679653_+	hypothetical protein	M1Q167	Streptococcus_phage	4.2e-40	37.7
WP_041174190.1\|679634_681611_+\|tail	phage tail protein	M1PKG3	Streptococcus_phage	2.2e-97	49.1
WP_011888772.1\|681607_682624_+	hyaluronoglucosaminidase	Q938K0	Temperate_phage	4.5e-147	81.4
WP_011888773.1\|682638_684423_+	hypothetical protein	Q938J9	Temperate_phage	2.6e-97	48.3
WP_011888774.1\|684434_684863_+	DUF1617 family protein	Q938J8	Temperate_phage	2.4e-62	88.6
WP_011888775.1\|684865_685498_+	hypothetical protein	Q938J7	Temperate_phage	2.9e-43	49.5
WP_002988799.1\|685508_685808_+	hypothetical protein	Q938J6	Temperate_phage	3.5e-36	82.3
WP_011888776.1\|685804_685990_+	hypothetical protein	Q938J5	Temperate_phage	1.2e-23	91.8
WP_011888778.1\|686103_687327_+	glucosaminidase domain-containing protein	A0A1P8VVM5	Streptococcus_phage	3.7e-164	60.5
WP_011888780.1\|687613_688585_+	Abi family protein	A0A059NT88	Lactococcus_phage	3.3e-75	42.3
WP_011888781.1\|688768_688969_+	CsbD family protein	J7KJ36	Streptococcus_phage	5.3e-20	81.8
WP_011888782.1\|689190_689985_+	DNA/RNA non-specific endonuclease	A7J2B8	Streptococcus_phage	8.9e-26	35.6
WP_011888783.1\|690050_690233_+	hypothetical protein	A3F673	Streptococcus_phage	1.1e-21	81.7
WP_011888784.1\|690764_692627_+	cadmium-translocating P-type ATPase	E4ZFI9	Streptococcus_phage	7.0e-90	34.1
690403:690422	attR	NA	NA	NA	NA
WP_011017962.1\|692698_692872_+	hypothetical protein	NA	NA	NA	NA
WP_011888785.1\|692926_693862_-	dihydroorotate oxidase	A0A1V0SH91	Hokovirus	7.9e-66	45.5

DBSCAN-SWA_3

1010354 : 1072678

Streptococcus_phage(70.59%)

transposase,head,tail,terminase,portal,integrase,capsid

attL 1030089:1030137|attR 1069906:1069954

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_111677588.1\|1010354_1010516_-\|transposase	IS3 family transposase	NA	NA	NA	NA
WP_011888918.1\|1010819_1012583_-	dihydrolipoyl dehydrogenase	A0A2K5B2C5	Erysipelothrix_phage	2.6e-33	25.3
WP_011017711.1\|1012913_1014323_-	dihydrolipoamide acetyltransferase	NA	NA	NA	NA
WP_041174208.1\|1014507_1015506_-	alpha-ketoacid dehydrogenase subunit beta	NA	NA	NA	NA
WP_002989983.1\|1015564_1016533_-	thiamine pyrophosphate-dependent dehydrogenase E1 component subunit alpha	NA	NA	NA	NA
WP_011888920.1\|1016817_1018725_-	ABC-F family ATP-binding cassette domain-containing protein	A0A2K9L3Z8	Tupanvirus	3.4e-55	30.9
WP_011017709.1\|1018770_1019097_-	hypothetical protein	NA	NA	NA	NA
WP_002984871.1\|1019126_1019912_-	esterase family protein	NA	NA	NA	NA
WP_002984872.1\|1020044_1021706_-	ribonuclease J	NA	NA	NA	NA
WP_011017707.1\|1021909_1022668_-	ABC transporter ATP-binding protein	A0A1V0SE00	Indivirus	5.9e-11	28.3
WP_002991975.1\|1022664_1023534_-	ABC transporter permease	NA	NA	NA	NA
WP_011184452.1\|1023878_1024877_-	ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_011888922.1\|1025230_1026883_+	PavA family fibronectin-binding protein Fbp54	A0A1J0F9J4	Only_Syngen_Nebraska_virus	1.7e-07	41.0
WP_002984878.1\|1026941_1028189_-	tetratricopeptide repeat protein	NA	NA	NA	NA
WP_002990002.1\|1028178_1029360_-	AI-2E family transporter	NA	NA	NA	NA
WP_011017701.1\|1029417_1029894_-	8-oxo-dGTP diphosphatase	NA	NA	NA	NA
1030089:1030137	attL	NA	NA	NA	NA
WP_010922229.1\|1030497_1031208_-	streptococcal pyrogenic exotoxin SpeH	NA	NA	NA	NA
WP_011888923.1\|1032183_1033518_-	lysin	Q5MY96	Streptococcus_phage	5.0e-247	92.8
WP_002990010.1\|1033629_1033815_-	hypothetical protein	Q938J5	Temperate_phage	1.9e-24	95.1
WP_002990012.1\|1033811_1034108_-	hypothetical protein	Q938J6	Temperate_phage	3.7e-46	98.0
WP_011888924.1\|1034117_1034750_-	hypothetical protein	Q938J7	Temperate_phage	5.2e-45	50.0
WP_011888925.1\|1034752_1035181_-	DUF1617 family protein	Q938J8	Temperate_phage	3.1e-57	82.1
WP_011888926.1\|1035192_1037079_-	gp58-like family protein	Q938J9	Temperate_phage	1.7e-208	82.3
WP_011888927.1\|1037093_1038209_-	hyaluronoglucosaminidase	Q938K0	Temperate_phage	1.6e-142	74.9
WP_011888928.1\|1038205_1040185_-\|tail	phage tail protein	A7J2A7	Streptococcus_phage	0.0e+00	92.8
WP_011054865.1\|1040194_1041037_-	hypothetical protein	A7J2A6	Streptococcus_phage	8.8e-157	97.9
WP_011888929.1\|1041048_1045431_-	tape measure protein	A7J2A5	Streptococcus_phage	2.5e-226	75.2
WP_011888930.1\|1045445_1045679_-	hypothetical protein	A7J2A4	Streptococcus_phage	1.3e-33	98.7
WP_011888931.1\|1045753_1046209_-	hypothetical protein	A7J2A3	Streptococcus_phage	5.3e-76	99.3
WP_011054869.1\|1046262_1046862_-\|tail	phage major tail protein, TP901-1 family	A7J2A2	Streptococcus_phage	1.7e-90	97.1
WP_011054870.1\|1046873_1047233_-	hypothetical protein	A7J2A1	Streptococcus_phage	1.2e-57	98.3
WP_011106640.1\|1047236_1047581_-	HK97 gp10 family phage protein	A7J2A0	Streptococcus_phage	5.1e-55	98.2
WP_011054872.1\|1047577_1047856_-	hypothetical protein	A7J299	Streptococcus_phage	1.9e-47	100.0
WP_011888932.1\|1047866_1048223_-\|head,tail	phage head-tail connector protein	A7J298	Streptococcus_phage	7.9e-59	99.2
WP_002983429.1\|1048234_1049122_-	hypothetical protein	A7J297	Streptococcus_phage	2.1e-161	100.0
WP_011888933.1\|1049134_1049704_-	DUF4355 domain-containing protein	A7J296	Streptococcus_phage	1.9e-83	100.0
WP_011888934.1\|1049865_1050132_-	hypothetical protein	Q938K9	Temperate_phage	2.9e-37	96.6
WP_011054876.1\|1050136_1050325_-	hypothetical protein	A7J294	Streptococcus_phage	7.4e-24	100.0
WP_032465703.1\|1050352_1051801_-\|capsid	minor capsid protein	A7J293	Streptococcus_phage	1.2e-278	99.8
WP_011888936.1\|1051760_1053293_-\|portal	phage portal protein	A7J292	Streptococcus_phage	2.2e-291	99.6
WP_011888937.1\|1053308_1054586_-\|terminase	PBSX family phage terminase large subunit	A7J291	Streptococcus_phage	6.9e-246	99.8
WP_011106637.1\|1054575_1055028_-\|terminase	terminase small subunit	A7J290	Streptococcus_phage	6.9e-76	100.0
WP_011888938.1\|1055117_1055534_-	transcriptional regulator	A7J289	Streptococcus_phage	9.5e-72	98.6
WP_011054882.1\|1055666_1055939_-	hypothetical protein	A7J287	Streptococcus_phage	5.7e-25	73.3
WP_023079587.1\|1055931_1056102_-	hypothetical protein	A7J285	Streptococcus_phage	2.8e-22	98.1
WP_011888939.1\|1056102_1057425_-	DEAD/DEAH box helicase family protein	A7J284	Streptococcus_phage	5.6e-251	97.3
WP_011054885.1\|1057421_1057697_-	VRR-NUC domain-containing protein	A7J283	Streptococcus_phage	2.9e-45	96.7
WP_011888940.1\|1058082_1060467_-	DNA primase	A7J282	Streptococcus_phage	1.6e-275	94.2
WP_011888941.1\|1060471_1062394_-	DNA polymerase	A7J280	Streptococcus_phage	0.0e+00	99.1
WP_086934854.1\|1062436_1063000_-	DUF2815 family protein	D2J040	Enterococcus_phage	3.3e-51	58.5
WP_011888943.1\|1063008_1064166_-	DUF2800 domain-containing protein	A7J278	Streptococcus_phage	1.0e-216	98.2
WP_002988708.1\|1064165_1064465_-	hypothetical protein	A7J277	Streptococcus_phage	1.8e-43	100.0
WP_002983407.1\|1064552_1064756_-	hypothetical protein	A7J276	Streptococcus_phage	9.4e-33	100.0
WP_012560645.1\|1064901_1065288_-	hypothetical protein	A7J274	Streptococcus_phage	4.3e-58	89.0
WP_012560644.1\|1065284_1065488_-	hypothetical protein	NA	NA	NA	NA
WP_011888947.1\|1065480_1065651_-	hypothetical protein	A7J273	Streptococcus_phage	1.2e-20	89.3
WP_011888948.1\|1065652_1065964_-	hypothetical protein	A1EAC3	Streptococcus_phage	5.0e-49	86.3
WP_001112862.1\|1066042_1066234_-	hypothetical protein	A0A141DZR9	Streptococcus_phage	4.7e-18	69.8
WP_011888949.1\|1066284_1067073_+	hypothetical protein	NA	NA	NA	NA
WP_011888950.1\|1067098_1067269_-	hypothetical protein	X2L066	Streptococcus_phage	5.1e-08	55.8
WP_011888951.1\|1067564_1067915_+	helix-turn-helix transcriptional regulator	M1PKY8	Streptococcus_phage	1.6e-35	62.6
WP_011888952.1\|1067917_1068304_+	hypothetical protein	M1PFJ2	Streptococcus_phage	7.3e-34	55.5
WP_011285632.1\|1068315_1068582_+	DUF4177 domain-containing protein	NA	NA	NA	NA
WP_011888953.1\|1068709_1069849_+\|integrase	site-specific integrase	A1EAB7	Streptococcus_phage	1.2e-119	56.3
WP_002984881.1\|1069931_1070972_-	dTDP-glucose 4,6-dehydratase	A0A1D7XFE8	Escherichia_phage	1.1e-68	43.9
1069906:1069954	attR	NA	NA	NA	NA
WP_002990099.1\|1071215_1071809_-	dTDP-4-dehydrorhamnose 3,5-epimerase	H9NC63	Sphingomonas_phage	3.7e-08	28.2
WP_002992970.1\|1071808_1072678_-	glucose-1-phosphate thymidylyltransferase RfbA	K7QKA7	Escherichia_phage	2.4e-101	64.6

DBSCAN-SWA_4

1175890 : 1186493

Streptococcus_phage(57.14%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_011889000.1\|1175890_1177033_-	cysteine desulfurase	A0A1X6WFP1	Pacmanvirus	6.3e-25	27.5
WP_011889001.1\|1177267_1177708_+	hypothetical protein	NA	NA	NA	NA
WP_011889002.1\|1177737_1179006_+	bifunctional folylpolyglutamate synthase/dihydrofolate synthase	NA	NA	NA	NA
WP_011889003.1\|1179093_1180446_-	glutathione-disulfide reductase	A0A2K5B2C5	Erysipelothrix_phage	1.0e-29	24.7
WP_002985134.1\|1180666_1181008_-	YlbF/YmcA family competence regulator	A0A1X9I5Y8	Streptococcus_phage	5.9e-19	40.2
WP_011889004.1\|1181068_1182235_-	chorismate synthase	A0A291AU41	Pandoravirus	5.8e-34	32.8
WP_002985140.1\|1182328_1183015_-	type I 3-dehydroquinate dehydratase	W6LP76	Streptococcus_phage	7.0e-88	68.9
WP_011889005.1\|1183011_1184175_-	class I SAM-dependent rRNA methyltransferase	W6LLI2	Streptococcus_phage	2.6e-143	65.1
WP_011889006.1\|1184282_1186493_+	LTA synthase family protein	W6LM83	Streptococcus_phage	6.5e-268	68.9

DBSCAN-SWA_5

1221921 : 1314683

104

Streptococcus_phage(53.97%)

head,tRNA,holin,tail,protease,terminase,portal,capsid

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_011889021.1\|1221921_1224327_-\|tRNA	phenylalanine--tRNA ligase subunit beta	NA	NA	NA	NA
WP_003057440.1\|1224536_1225580_-\|tRNA	phenylalanine--tRNA ligase subunit alpha	A0A2K9L3A8	Tupanvirus	4.6e-30	34.3
WP_011017613.1\|1226761_1226950_-	DNA-directed RNA polymerase subunit beta	NA	NA	NA	NA
WP_002994428.1\|1226953_1228225_-	UDP-N-acetylglucosamine 1-carboxyvinyltransferase	NA	NA	NA	NA
WP_011889022.1\|1228289_1228547_-	DUF1146 domain-containing protein	NA	NA	NA	NA
WP_002994425.1\|1228812_1229229_-	F0F1 ATP synthase subunit epsilon	NA	NA	NA	NA
WP_003057452.1\|1229241_1230648_-	F0F1 ATP synthase subunit beta	NA	NA	NA	NA
WP_002985236.1\|1230810_1231686_-	F0F1 ATP synthase subunit gamma	NA	NA	NA	NA
WP_011889023.1\|1231704_1233210_-	F0F1 ATP synthase subunit alpha	NA	NA	NA	NA
WP_002985240.1\|1233225_1233762_-	F0F1 ATP synthase subunit delta	NA	NA	NA	NA
WP_002985242.1\|1233761_1234256_-	F0F1 ATP synthase subunit B	NA	NA	NA	NA
WP_011889024.1\|1234273_1234990_-	F0F1 ATP synthase subunit A	NA	NA	NA	NA
WP_002985249.1\|1235024_1235222_-	F0F1 ATP synthase subunit C	NA	NA	NA	NA
WP_011017609.1\|1235613_1236636_-	diacylglycerol kinase family lipid kinase	A0A1V0SBJ0	Catovirus	3.6e-19	27.9
WP_011017608.1\|1236649_1238608_-	NAD-dependent DNA ligase LigA	A0A0K2QQN8	Ralstonia_phage	9.9e-103	34.9
WP_011017607.1\|1238801_1239302_-	QueT transporter family protein	E7DN70	Pneumococcus_phage	5.4e-05	32.4
WP_011889025.1\|1239579_1242312_-	endonuclease/exonuclease/phosphatase family protein	NA	NA	NA	NA
WP_011889027.1\|1242884_1244003_-	ABC transporter permease	NA	NA	NA	NA
WP_002985266.1\|1243999_1245127_-	ABC transporter permease	NA	NA	NA	NA
WP_002990429.1\|1245135_1246059_-	ABC transporter ATP-binding protein	W6JKT0	Anomala_cuprea_entomopoxvirus	6.7e-33	38.1
WP_002985270.1\|1246081_1246765_-	hypothetical protein	NA	NA	NA	NA
WP_002985272.1\|1246761_1247433_-\|protease	CPBP family intramembrane metalloprotease	NA	NA	NA	NA
WP_011889028.1\|1247407_1248766_-	YcaO-like family protein	NA	NA	NA	NA
WP_002985275.1\|1248785_1249844_-	streptolysin associated protein SagC	NA	NA	NA	NA
WP_002990438.1\|1249840_1250791_-	streptolysin S biosynthesis dehydrogenase SagB	NA	NA	NA	NA
WP_002985285.1\|1251012_1251174_-	TOMM family cytolysin streptolysin S	NA	NA	NA	NA
WP_002985288.1\|1251943_1253251_-	phosphopyruvate hydratase	A0A1X9I5Z8	Streptococcus_phage	1.2e-240	96.6
WP_011889029.1\|1253477_1253939_+	YueI family protein	W6LLD2	Streptococcus_phage	1.1e-17	39.5
WP_011017601.1\|1254070_1255795_-	septation ring formation regulator EzrA	NA	NA	NA	NA
WP_011889030.1\|1256162_1258115_-	DNA topoisomerase (ATP-hydrolyzing) subunit B	G3M9Z3	Bacillus_virus	8.9e-144	45.9
WP_002994056.1\|1258115_1258685_-	hydrolase	NA	NA	NA	NA
WP_002985298.1\|1259699_1260047_-	50S ribosomal protein L19	NA	NA	NA	NA
WP_011889031.1\|1260161_1261424_-	chloride channel protein	A0A1X9I5Z9	Streptococcus_phage	3.2e-94	50.5
WP_011889032.1\|1261416_1261701_-	chorismate mutase	NA	NA	NA	NA
WP_002985303.1\|1261875_1262325_-	flavodoxin	NA	NA	NA	NA
WP_011017597.1\|1262718_1263660_+	bifunctional oligoribonuclease/PAP phosphatase NrnA	NA	NA	NA	NA
WP_002985307.1\|1263774_1264035_+	type B 50S ribosomal protein L31	NA	NA	NA	NA
WP_011889033.1\|1264131_1265331_-	SIS domain-containing protein	NA	NA	NA	NA
WP_011889034.1\|1265350_1266073_-	GntR family transcriptional regulator	NA	NA	NA	NA
WP_011889035.1\|1266229_1267777_-	zinc ABC transporter substrate-binding protein AdcA	NA	NA	NA	NA
WP_038433138.1\|1267928_1269347_-	C69 family dipeptidase	NA	NA	NA	NA
WP_002985324.1\|1269658_1270417_+	DNase Mf2	NA	NA	NA	NA
WP_002985327.1\|1270527_1271235_+	streptococcal pyrogenic exotoxin SpeC	A0A097PAT7	Streptococcus_pyogenes_phage	3.9e-09	27.1
WP_002985329.1\|1271302_1272508_-	glucosaminidase domain-containing protein	Q938J4	Temperate_phage	1.6e-204	83.3
WP_000609113.1\|1272623_1272851_-\|holin	phage holin	A7J2B3	Streptococcus_phage	5.8e-31	98.7
WP_002987582.1\|1272847_1273123_-	hypothetical protein	A7J2B2	Streptococcus_phage	2.6e-41	100.0
WP_011017592.1\|1273132_1273750_-	DUF1366 domain-containing protein	Q938J7	Temperate_phage	5.0e-77	89.3
WP_002983467.1\|1273752_1274184_-	DUF1617 family protein	Q938J8	Temperate_phage	1.3e-63	89.5
WP_011889036.1\|1274195_1276082_-	gp58-like family protein	Q938J9	Temperate_phage	3.4e-217	84.6
WP_011017589.1\|1276094_1277105_-	hyaluronoglucosaminidase	Q938K0	Temperate_phage	7.8e-136	75.8
WP_011527560.1\|1277101_1279246_-\|tail	phage tail protein	Q938K1	Temperate_phage	0.0e+00	94.7
WP_011527559.1\|1279242_1279950_-\|tail	phage tail family protein	Q938K2	Temperate_phage	6.8e-94	71.9
WP_002985338.1\|1279949_1283873_-\|tail	phage tail tape measure protein	J7KDT4	Streptococcus_phage	1.9e-238	48.5
WP_021299462.1\|1283885_1284035_-	hypothetical protein	J7KBS0	Streptococcus_phage	1.7e-15	85.7
WP_011017586.1\|1284082_1284409_-	hypothetical protein	J7KK85	Streptococcus_phage	8.3e-39	75.0
WP_011017585.1\|1284461_1285070_-	hypothetical protein	J7KKC8	Streptococcus_phage	6.7e-74	71.9
WP_011017584.1\|1285085_1285511_-	hypothetical protein	J7KBZ9	Streptococcus_phage	7.2e-67	84.4
WP_011527557.1\|1285507_1285885_-	HK97 gp10 family phage protein	J7KDM3	Streptococcus_phage	1.8e-45	72.8
WP_011017582.1\|1285881_1286229_-\|head	phage head closure protein	J7KJ42	Streptococcus_phage	2.9e-50	88.2
WP_011017581.1\|1286225_1286528_-\|head,tail	phage head-tail connector protein	J7KC36	Streptococcus_phage	1.3e-41	88.8
WP_011017580.1\|1286672_1287860_-\|capsid	phage major capsid protein	J7KJ82	Streptococcus_phage	1.3e-158	74.7
WP_011017579.1\|1287884_1288550_-\|protease	Clp protease ClpP	M1Q115	Streptococcus_phage	3.5e-92	78.1
WP_011017578.1\|1288527_1289748_-\|portal	phage portal protein	J7KDU3	Streptococcus_phage	6.9e-187	81.9
WP_002985363.1\|1289781_1290006_-	hypothetical protein	Q938K9	Temperate_phage	3.6e-17	61.4
WP_002985365.1\|1289998_1290169_-	hypothetical protein	J7KK43	Streptococcus_phage	2.3e-08	62.5
WP_024623442.1\|1290165_1291920_-	amino acid transporter	J7KKD1	Streptococcus_phage	0.0e+00	96.1
WP_002985368.1\|1291923_1292154_-	hypothetical protein	NA	NA	NA	NA
WP_002985371.1\|1292156_1292624_-\|terminase	phage terminase small subunit P27 family	J7KC46	Streptococcus_phage	3.9e-82	98.7
WP_002985375.1\|1292794_1293133_-	HNH endonuclease	J7KH36	Streptococcus_phage	3.0e-55	90.7
WP_001132273.1\|1293368_1293554_+	type II toxin-antitoxin system HicA family toxin	D6PSW1	Lactobacillus_phage	1.7e-09	54.0
WP_002987543.1\|1293605_1293983_+	type II toxin-antitoxin system HicB family antitoxin	I3NLB2	Bifidobacterium_phage	3.3e-15	44.0
WP_011017575.1\|1294109_1295039_-	DNA adenine methylase	A0A126HAU2	Lactococcus_phage	4.9e-100	71.8
WP_011017574.1\|1295621_1296059_-	DUF1492 domain-containing protein	A0A097PBF1	Streptococcus_pyogenes_phage	6.7e-76	97.9
WP_002987471.1\|1296328_1296964_-	SAM-dependent DNA methyltransferase	L0P368	Streptococcus_phage	5.5e-87	67.9
WP_002987468.1\|1296963_1297365_-	hypothetical protein	NA	NA	NA	NA
WP_011017571.1\|1297555_1298038_-	class I SAM-dependent methyltransferase	A0A097PAU8	Streptococcus_pyogenes_phage	9.6e-92	98.8
WP_011889038.1\|1298041_1298326_-	hypothetical protein	A0A097PAV1	Streptococcus_pyogenes_phage	1.0e-37	88.3
WP_011017569.1\|1298322_1298736_-	hypothetical protein	Q938M1	Temperate_phage	6.4e-36	65.2
WP_002987593.1\|1298745_1299015_-	hypothetical protein	A0A1P8VVR6	Streptococcus_phage	3.1e-47	100.0
WP_011017568.1\|1299011_1299296_-	DUF3310 domain-containing protein	A0A1P8VVP5	Streptococcus_phage	7.0e-50	100.0
WP_002985380.1\|1299473_1299986_-	hypothetical protein	Q708P9	Streptococcus_phage	8.4e-62	73.2
WP_002985383.1\|1299982_1300324_-	hypothetical protein	M1NS23	Streptococcus_phage	3.1e-12	38.7
WP_002988362.1\|1300500_1301298_-	PD-(D/E)XK nuclease-like domain-containing protein	J7KGZ1	Streptococcus_phage	6.6e-130	83.8
WP_000594115.1\|1301290_1301491_-	hypothetical protein	NA	NA	NA	NA
WP_010922474.1\|1301487_1302477_-	recombinase RecT	A0A286QMX3	Streptococcus_phage	5.8e-59	44.2
WP_010922475.1\|1302476_1302809_-	hypothetical protein	J7KGX3	Streptococcus_phage	2.2e-42	78.7
WP_011017565.1\|1302864_1303071_-	hypothetical protein	NA	NA	NA	NA
WP_011017992.1\|1303079_1303220_-	hypothetical protein	NA	NA	NA	NA
WP_002985387.1\|1303216_1303450_-	hypothetical protein	Q938N1	Temperate_phage	6.1e-36	94.8
WP_002985388.1\|1303430_1303817_-	DnaD domain-containing protein	Q938N2	Temperate_phage	2.8e-25	55.0
WP_002985392.1\|1304314_1304500_-	hypothetical protein	Q938N3	Temperate_phage	2.0e-21	83.6
WP_002985395.1\|1304501_1304639_-	hypothetical protein	NA	NA	NA	NA
WP_011889039.1\|1304725_1304908_+	hypothetical protein	NA	NA	NA	NA
WP_002985404.1\|1305048_1305810_-	phage repressor protein/antirepressor Ant	A0A0C5AEJ9	Bacteriophage	1.6e-85	61.9
WP_002985407.1\|1305858_1306047_-	helix-turn-helix transcriptional regulator	A0A0B5A7F0	Streptococcus_phage	2.6e-13	63.3
WP_001008979.1\|1306098_1306740_+	hypothetical protein	J7KJ31	Streptococcus_phage	1.5e-116	100.0
WP_002985414.1\|1306838_1306997_-	hypothetical protein	J7KH24	Streptococcus_phage	7.1e-20	88.5
WP_002985417.1\|1307356_1308121_+	helix-turn-helix transcriptional regulator	E8ZDN4	Streptococcus_phage	2.0e-83	64.5
WP_002985420.1\|1308130_1308436_+	membrane protein	NA	NA	NA	NA
WP_011017563.1\|1308558_1309974_+	recombinase family protein	A5GZ62	Lactococcus_phage	1.4e-109	47.2
WP_011017562.1\|1310150_1311062_-	DNA-binding protein WhiA	Q7AWZ3	Streptococcus_phage	2.9e-105	64.4
WP_011889040.1\|1311058_1312036_-	YvcK family protein	A1IMD5	Streptococcus_phage	4.0e-137	73.8
WP_002985434.1\|1312032_1312923_-	RNase adapter RapZ	A0A0R8VB27	Thermobifida_phage	8.8e-06	29.8
WP_002985437.1\|1313336_1314683_-\|tRNA	asparagine--tRNA ligase	A0A2P1EMB4	Moumouvirus	1.1e-55	30.8

DBSCAN-SWA_6

1387936 : 1394433

Streptococcus_phage(66.67%)

portal

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_023077463.1\|1387936_1388614_-	asparagine synthetase A	A0A167RLM0	Powai_lake_megavirus	3.1e-11	28.6
WP_011017510.1\|1388637_1388976_-	Fic family protein	NA	NA	NA	NA
WP_009880563.1\|1389392_1389701_-	hypothetical protein	Q6DMT0	Streptococcus_phage	3.7e-20	62.2
WP_009880562.1\|1389766_1390219_-\|portal	phage portal protein	E4ZFM3	Streptococcus_phage	4.4e-62	85.6
WP_002985604.1\|1390322_1390595_-	hypothetical protein	E4ZFM1	Streptococcus_phage	4.1e-07	50.7
WP_011889070.1\|1390613_1390919_-	type II toxin-antitoxin system RelE/ParE family toxin	NA	NA	NA	NA
WP_002991611.1\|1390918_1391221_-	type II toxin-antitoxin system RelB/DinJ family antitoxin	NA	NA	NA	NA
WP_014635353.1\|1391275_1391452_-	hypothetical protein	M1PSF2	Streptococcus_phage	1.2e-20	86.2
WP_162009224.1\|1391476_1392361_+	hypothetical protein	NA	NA	NA	NA
WP_001176803.1\|1392360_1392585_+	hypothetical protein	NA	NA	NA	NA
WP_002990647.1\|1393760_1394234_+	DUF2326 domain-containing protein	NA	NA	NA	NA
WP_011889073.1\|1394223_1394433_+	helix-turn-helix domain-containing protein	A0A2K5B263	Erysipelothrix_phage	4.8e-16	60.0

DBSCAN-SWA_7

1451035 : 1506731

Streptococcus_phage(33.33%)

bacteriocin,tRNA,protease

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_002985729.1\|1451035_1451236_-\|bacteriocin	class IIb bacteriocin, lactobin A/cerein 7B family	NA	NA	NA	NA
WP_002992018.1\|1451248_1451476_-\|bacteriocin	bacteriocin	NA	NA	NA	NA
WP_002987564.1\|1452670_1452853_-\|bacteriocin	class IIb bacteriocin, lactobin A/cerein 7B family	NA	NA	NA	NA
WP_002994504.1\|1452867_1453113_-\|bacteriocin	bacteriocin	NA	NA	NA	NA
WP_002985741.1\|1454070_1454547_-	NUDIX hydrolase	NA	NA	NA	NA
WP_002985743.1\|1454566_1455463_-	GTPase Era	NA	NA	NA	NA
WP_002985746.1\|1455582_1455990_-	diacylglycerol kinase	NA	NA	NA	NA
WP_002985748.1\|1455970_1456468_-	rRNA maturation RNase YbeY	NA	NA	NA	NA
WP_002990783.1\|1456626_1457202_-	uracil-DNA glycosylase family protein	NA	NA	NA	NA
WP_002985751.1\|1457247_1458300_-	PhoH family protein	W8D063	Erwinia_phage	1.2e-46	50.0
WP_011889097.1\|1458458_1460231_-	oleate hydratase	NA	NA	NA	NA
WP_011889098.1\|1460545_1461703_-	LysM peptidoglycan-binding domain-containing protein	A0A0E3XB61	Gordonia_phage	5.4e-16	40.5
WP_002985757.1\|1461858_1462074_-	YozE family protein	NA	NA	NA	NA
WP_002985759.1\|1462070_1462580_-	peptide-methionine (S)-S-oxide reductase MsrA	NA	NA	NA	NA
WP_011889099.1\|1462652_1463510_-	S1 RNA-binding domain-containing protein	NA	NA	NA	NA
WP_002985763.1\|1463618_1464176_-	ribosome recycling factor	NA	NA	NA	NA
WP_002985765.1\|1464204_1464933_-	UMP kinase	NA	NA	NA	NA
WP_002985768.1\|1465254_1465944_-	50S ribosomal protein L1	NA	NA	NA	NA
WP_002990800.1\|1466049_1466475_-	50S ribosomal protein L11	NA	NA	NA	NA
WP_086934860.1\|1466699_1466996_+	DUF3397 domain-containing protein	NA	NA	NA	NA
WP_011889100.1\|1467065_1469471_-	DNA translocase FtsK	S5VNE3	Mycobacterium_phage	3.8e-88	51.7
WP_002985776.1\|1469687_1470494_+	peptidylprolyl isomerase	A0A2H4UTF4	Bodo_saltans_virus	1.5e-20	36.6
WP_011889101.1\|1470641_1471496_-	metal ABC transporter permease	NA	NA	NA	NA
WP_011889102.1\|1471496_1472222_-	metal ABC transporter ATP-binding protein	A0A1V0SE00	Indivirus	4.8e-18	33.0
WP_011889103.1\|1472285_1473218_-	metal ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_011184242.1\|1473363_1474011_+	metal-dependent transcriptional regulator	NA	NA	NA	NA
WP_011184241.1\|1474109_1474451_-	hypothetical protein	NA	NA	NA	NA
WP_011889104.1\|1474601_1475297_-	5'-methylthioadenosine/adenosylhomocysteine nucleosidase	NA	NA	NA	NA
WP_002990826.1\|1475316_1475568_-	hypothetical protein	NA	NA	NA	NA
WP_011889105.1\|1475567_1476122_-	NUDIX hydrolase	NA	NA	NA	NA
WP_011889106.1\|1476152_1477535_-	bifunctional UDP-N-acetylglucosamine diphosphorylase/glucosamine-1-phosphate N-acetyltransferase GlmU	A0A2K9L4K9	Tupanvirus	3.8e-32	36.4
WP_002993065.1\|1477708_1479046_-	MFS transporter	NA	NA	NA	NA
WP_011889107.1\|1479378_1480338_-	Gfo/Idh/MocA family oxidoreductase	NA	NA	NA	NA
WP_011889108.1\|1480413_1481112_-	3-oxoacyl-ACP reductase	A0A0N9R355	Chrysochromulina_ericina_virus	1.0e-09	25.2
WP_002990844.1\|1481104_1481341_-	DUF2829 domain-containing protein	NA	NA	NA	NA
WP_011889109.1\|1481703_1482204_+	hypothetical protein	NA	NA	NA	NA
WP_023077780.1\|1482297_1482549_-	hypothetical protein	NA	NA	NA	NA
WP_011889111.1\|1482744_1483209_-	hypothetical protein	NA	NA	NA	NA
WP_011889112.1\|1483669_1484422_+	ADP-ribosyltransferase	NA	NA	NA	NA
WP_011054229.1\|1484626_1486807_-	class 1b ribonucleoside-diphosphate reductase subunit alpha	A8E2R1	Enterococcus_phage	1.2e-170	43.2
WP_002990870.1\|1486773_1487262_-	class Ib ribonucleoside-diphosphate reductase assembly flavoprotein NrdI	R4JF54	Bacillus_phage	1.3e-11	37.5
WP_011889113.1\|1487265_1488279_-	class 1b ribonucleoside-diphosphate reductase subunit beta	R4TBI6	Mycobacterium_phage	7.2e-97	53.0
WP_011184224.1\|1488773_1490774_-\|tRNA	methionine--tRNA ligase	A0A1V0SHR2	Klosneuvirus	4.6e-87	35.1
WP_010921939.1\|1491013_1491721_-	DUF1275 domain-containing protein	NA	NA	NA	NA
WP_011889116.1\|1492492_1497433_-\|protease	CXC chemokine-degrading serine protease SpyCEP	NA	NA	NA	NA
WP_011889117.1\|1497698_1498880_-	L-lactate oxidase	NA	NA	NA	NA
WP_011889118.1\|1499113_1499941_+	exodeoxyribonuclease III	M1PSC0	Streptococcus_phage	4.5e-129	79.3
WP_002995120.1\|1500014_1500371_-	arsenate reductase family protein	M1PLC0	Streptococcus_phage	2.8e-40	66.7
WP_009880724.1\|1500670_1501300_+	copper homeostasis protein CutC	NA	NA	NA	NA
WP_011889119.1\|1501296_1501713_-	hypothetical protein	NA	NA	NA	NA
WP_002985836.1\|1501739_1502603_-	16S rRNA (cytidine(1402)-2'-O)-methyltransferase	M1PLC5	Streptococcus_phage	1.7e-115	75.0
WP_002985838.1\|1502607_1502931_-	DNA replication initiation control protein YabA	M1PFV3	Streptococcus_phage	1.3e-28	59.4
WP_011017422.1\|1503335_1503575_-	hypothetical protein	NA	NA	NA	NA
WP_011889120.1\|1503593_1504469_-	DNA polymerase III subunit delta'	M1NSC1	Streptococcus_phage	1.0e-62	44.4
WP_011017420.1\|1504486_1505122_-	dTMP kinase	M1PSC7	Streptococcus_phage	3.5e-65	63.4
WP_002985847.1\|1505370_1505646_-	YlbG family protein	NA	NA	NA	NA
WP_002985850.1\|1506140_1506731_-\|protease	ATP-dependent Clp protease proteolytic subunit	A0A223W000	Agrobacterium_phage	2.6e-54	55.7

DBSCAN-SWA_8

1761596 : 1781322

Streptococcus_phage(60.0%)

tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_011889221.1\|1761596_1763579_-	DNA mismatch repair endonuclease MutL	A0A1B2LRQ5	Wolbachia_phage	2.3e-62	30.1
WP_011889222.1\|1765034_1766024_-	DUF3644 domain-containing protein	A0A0N9RUA4	Staphylococcus_phage	2.8e-77	47.0
WP_011889223.1\|1766049_1766325_-	helix-turn-helix domain-containing protein	O48392	Streptococcus_phage	6.4e-16	44.6
WP_011889224.1\|1766675_1767632_-	helix-turn-helix transcriptional regulator	A0A060QNS7	Streptococcus_phage	3.6e-13	39.3
WP_011889225.1\|1767786_1768020_+	helix-turn-helix transcriptional regulator	X2KUC2	Streptococcus_phage	5.8e-10	47.0
WP_011889226.1\|1768313_1768646_+	hypothetical protein	NA	NA	NA	NA
WP_011889227.1\|1768645_1768837_+	hypothetical protein	NA	NA	NA	NA
WP_003045763.1\|1768848_1769178_+	hypothetical protein	NA	NA	NA	NA
WP_011889228.1\|1769180_1769453_+	hypothetical protein	A0A1X9I5U9	Streptococcus_phage	5.2e-18	58.8
WP_011889229.1\|1769453_1770320_+	primase C-terminal domain-containing protein	A0A1X9I6L2	Streptococcus_phage	5.2e-120	73.4
WP_011889230.1\|1770339_1771842_+	DNA primase	Q9AZI5	Lactococcus_phage	7.0e-64	37.5
WP_011889231.1\|1772155_1772329_+	hypothetical protein	A0A1X9I5U0	Streptococcus_phage	5.1e-11	59.6
WP_011529113.1\|1772334_1772508_+	hypothetical protein	NA	NA	NA	NA
WP_023077351.1\|1772509_1773067_+	hypothetical protein	A0A1X9I5U4	Streptococcus_phage	1.9e-30	55.7
WP_011889233.1\|1773140_1773629_+	hypothetical protein	A0A1X9I5V2	Streptococcus_phage	5.1e-48	57.4
WP_011889234.1\|1774032_1774395_+	DUF1492 domain-containing protein	A0A2H4JFS1	uncultured_Caudovirales_phage	1.2e-06	31.6
WP_011889235.1\|1774369_1774753_+	ArpU family transcriptional regulator	A0A286QPF1	Streptococcus_phage	6.8e-08	34.7
WP_011889236.1\|1774954_1775617_+	hypothetical protein	NA	NA	NA	NA
WP_011185079.1\|1776011_1778567_-	DNA mismatch repair protein MutS	A0A1V0SGG8	Hokovirus	4.0e-43	23.3
WP_011889237.1\|1778553_1778760_-	YlbF family regulator	NA	NA	NA	NA
WP_002982171.1\|1778902_1779340_-	arginine repressor	NA	NA	NA	NA
WP_002991367.1\|1779630_1781322_+\|tRNA	arginine--tRNA ligase	A0A2I2L3K1	Orpheovirus	2.4e-73	32.2

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. NC_009332

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection