CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NC_009004	Lactococcus lactis subsp. cremoris MG1363, complete genome	1 crisprs	WYL,cas3,csa3,RT,DEDDh,DinG	0	0	12	0

Results visualization

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CRISPR-Cas detection and classification

Crispr_ID: NC_009004_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_009004_1

1484410-1484507

Orphan

Consensus_repeat	Method
CCTTTGGTCGTATTGAACTGACAGAA	CRISPRCasFinder

1 spacers

The CRISPR arrays of NC_009004_1

>merge|NC_009004|1|1484410-1484507|CRISPRCasFinder
CCTTTGGTCGTATTGAACTGACAGAACTATCAGCAAAGCTGATTGTTCATTTAGCTACCGATTCAATAACTCCCTTTGGTCGCATTGAACTGACAGAA

>NC_009004|1|1|1484410-1484507|CRISPRCasFinder
CCTTTGGTCGTATTGAACTGACAGAA	CTATCAGCAAAGCTGATTGTTCATTTAGCTACCGATTCAATAACTC
CCTTTGGTCGCATTGAACTGACAGAA

Protein	Signature genes	Signature genes Name	Protein_function
NC_009004.1\|WP_011835357.1\|1488358_1489042_-\|DNA-repair-protein-RadC	unknown	unknown	gnl\|CDD\|178801
NC_009004.1\|WP_011835346.1\|1471308_1471965_-\|endonuclease-III	unknown	unknown	gnl\|CDD\|223255
NC_009004.1\|WP_011835350.1\|1475840_1476767_-\|hypothetical-protein	unknown	unknown	unknown
NC_009004.1\|WP_011835352.1\|1480956_1482024_-\|SEL1-like-repeat-protein	unknown	unknown	gnl\|CDD\|276807
NC_009004.1\|WP_011835358.1\|1489159_1490977_-\|glutamine--fructose-6-phosphate-transaminase-(isomerizing)	unknown	unknown	gnl\|CDD\|234729
NC_009004.1\|WP_011835344.1\|1469856_1470630_-\|Nif3-like-dinuclear-metal-center-hexameric-protein	unknown	unknown	gnl\|CDD\|376614
NC_009004.1\|WP_011835351.1\|1476974_1480778_-\|bacterial-Ig-like-domain-containing-protein	unknown	unknown	unknown
NC_009004.1\|WP_011835354.1\|1483704_1484334_-\|orotate-phosphoribosyltransferase	unknown	unknown	gnl\|CDD\|234771
NC_009004.1\|WP_011835355.1\|1484826_1486734_-\|ATP-binding-cassette-domain-containing-protein	unknown	unknown	gnl\|CDD\|223562
NC_009004.1\|WP_011835345.1\|1470626_1471316_-\|tRNA-(adenine-N(1))-methyltransferase	unknown	unknown	gnl\|CDD\|225258
NC_009004.1\|WP_011835353.1\|1482281_1483553_-\|dihydroorotase	unknown	unknown	gnl\|CDD\|236479
NC_009004.1\|WP_011835359.1\|1491158_1491815_-\|phosphatase-PAP2-family-protein	unknown	unknown	gnl\|CDD\|239486
NC_009004.1\|WP_011835356.1\|1487521_1488172_+\|redox-sensing-transcriptional-repressor-Rex	unknown	unknown	gnl\|CDD\|225221
NC_009004.1\|WP_011835347.1\|1471986_1472655_-\|DnaD-domain-containing-protein	unknown	unknown	gnl\|CDD\|226445
NC_009004.1\|WP_011676069.1\|1486906_1487299_-\|transcriptional-regulator-Spx	unknown	unknown	gnl\|CDD\|239330
NC_009004.1\|WP_011835360.1\|1491824_1493150_-\|HAMP-domain-containing-protein	unknown	unknown	gnl\|CDD\|223715
NC_009004.1\|WP_011835348.1\|1472920_1475113_-\|BspA-family-leucine-rich-repeat-surface-protein	unknown	unknown	gnl\|CDD\|308794
NC_009004.1\|WP_153951976.1\|1484523_1484664_+\|hypothetical-protein	unknown	unknown	unknown
NC_009004.1\|WP_011835362.1\|1493689_1494376_-\|response-regulator-transcription-factor	unknown	unknown	gnl\|CDD\|223816
NC_009004.1\|WP_011835361.1\|1493153_1493669_-\|DUF2127-domain-containing-protein	unknown	unknown	gnl\|CDD\|226781

Protein	Function_ID	Function_description	E-value
NC_009004.1\|WP_011835346.1\|1471308_1471965_-\|endonuclease-III	gnl\|CDD\|223255	COG0177, Nth, Predicted EndoIII-related endonuclease [DNA replication, recombination, and repair].	1.30673e-108
NC_009004.1\|WP_011835357.1\|1488358_1489042_-\|DNA-repair-protein-RadC	gnl\|CDD\|178801	PRK00024, PRK00024, DNA repair protein RadC.	5.84967e-97
NC_009004.1\|WP_011835352.1\|1480956_1482024_-\|SEL1-like-repeat-protein	gnl\|CDD\|276807	sd00010, SLR, Sel1-like repeat. Sel1-like repeats (SLRs) share similar alpha-helical conformations with Tetratricopeptide repeats (TPRs), but with different consensus sequence lengths and superhelical topologies. SLRs contain 36 to 44 amino acids and are present in bacteria and eukaryotes but not in archaea. SLR proteins are involved in a variety of functions, and many serve as adaptor proteins for the assembly of macromolecular complexes. The SLR family was named after the Caenorhabditis elegans Sel1 protein which is predicted to fold into 11 SLRs, a transmembrane domain, and an N-terminal signal sequence. The human Sel1L protein contains an additional fibronectin type-II domain and an N-terminal PEST sequence. Its downregulation is associated with the development of breast and pancreatic carcinomas.	1.63546e-30
NC_009004.1\|WP_011835359.1\|1491158_1491815_-\|phosphatase-PAP2-family-protein	gnl\|CDD\|239486	cd03392, PAP2_like_2, PAP2_like_2 proteins. PAP2 is a super-family of phosphatases and haloperoxidases. This subgroup, which is specific to bacteria, lacks functional characterization and may act as a membrane-associated lipid phosphatase.	8.58999e-45
NC_009004.1\|WP_011835344.1\|1469856_1470630_-\|Nif3-like-dinuclear-metal-center-hexameric-protein	gnl\|CDD\|376614	pfam01784, NIF3, NIF3 (NGG1p interacting factor 3). This family contains several NIF3 (NGG1p interacting factor 3) protein homologs. NIF3 interacts with the yeast transcriptional coactivator NGG1p which is part of the ADA complex, the exact function of this interaction is unknown.	5.01288e-88
NC_009004.1\|WP_011835358.1\|1489159_1490977_-\|glutamine--fructose-6-phosphate-transaminase-(isomerizing)	gnl\|CDD\|234729	PRK00331, PRK00331, isomerizing glutamine--fructose-6-phosphate transaminase.	0
NC_009004.1\|WP_011835354.1\|1483704_1484334_-\|orotate-phosphoribosyltransferase	gnl\|CDD\|234771	PRK00455, pyrE, orotate phosphoribosyltransferase; Validated.	9.16895e-74
NC_009004.1\|WP_011835355.1\|1484826_1486734_-\|ATP-binding-cassette-domain-containing-protein	gnl\|CDD\|223562	COG0488, Uup, ATPase components of ABC transporters with duplicated ATPase domains [General function prediction only].	0
NC_009004.1\|WP_011835356.1\|1487521_1488172_+\|redox-sensing-transcriptional-repressor-Rex	gnl\|CDD\|225221	COG2344, COG2344, AT-rich DNA-binding protein [General function prediction only].	1.73114e-111
NC_009004.1\|WP_011835353.1\|1482281_1483553_-\|dihydroorotase	gnl\|CDD\|236479	PRK09357, pyrC, dihydroorotase; Validated.	0
NC_009004.1\|WP_011835345.1\|1470626_1471316_-\|tRNA-(adenine-N(1))-methyltransferase	gnl\|CDD\|225258	COG2384, COG2384, Predicted SAM-dependent methyltransferase [General function prediction only].	1.37364e-100
NC_009004.1\|WP_011835347.1\|1471986_1472655_-\|DnaD-domain-containing-protein	gnl\|CDD\|226445	COG3935, DnaD, Putative primosome component and related proteins [DNA replication, recombination, and repair].	1.85483e-64
NC_009004.1\|WP_011676069.1\|1486906_1487299_-\|transcriptional-regulator-Spx	gnl\|CDD\|239330	cd03032, ArsC_Spx, Arsenate Reductase (ArsC) family, Spx subfamily; Spx is a unique RNA polymerase (RNAP)-binding protein present in bacilli and some mollicutes. It inhibits transcription by binding to the C-terminal domain of the alpha subunit of RNAP, disrupting complex formation between RNAP and certain transcriptional activator proteins like ResD and ComA. In response to oxidative stress, Spx can also activate transcription, making it a general regulator that exerts both positive and negative control over transcription initiation. Spx has been shown to exert redox-sensitive transcriptional control over genes like trxA (TRX) and trxB (TRX reductase), genes that function in thiol homeostasis. This redox-sensitive activity is dependent on the presence of a CXXC motif, present in some members of the Spx subfamily, that acts as a thiol/disulfide switch. Spx has also been shown to repress genes in a sulfate-dependent manner independent of the presence of the CXXC motif.	2.21314e-55
NC_009004.1\|WP_011835360.1\|1491824_1493150_-\|HAMP-domain-containing-protein	gnl\|CDD\|223715	COG0642, BaeS, Signal transduction histidine kinase [Signal transduction mechanisms].	2.7038e-48
NC_009004.1\|WP_011835348.1\|1472920_1475113_-\|BspA-family-leucine-rich-repeat-surface-protein	gnl\|CDD\|308794	pfam03382, DUF285, Mycoplasma protein of unknown function, DUF285. This region appears distantly related to leucine rich repeats.	3.65234e-32
NC_009004.1\|WP_011835362.1\|1493689_1494376_-\|response-regulator-transcription-factor	gnl\|CDD\|223816	COG0745, OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription].	1.83306e-81
NC_009004.1\|WP_011835361.1\|1493153_1493669_-\|DUF2127-domain-containing-protein	gnl\|CDD\|226781	COG4331, COG4331, Predicted membrane protein [Function unknown].	1.23826e-54

>NC_009004.1|WP_011835354.1|1483704_1484334_-|orotate-phosphoribosyltransferase
MSISKAIAADLLEIKAVSLSPSQPFTWASGIKSPIYTDNRVTLAYPEVRSQIEGAFAELIKTEFPEVEVIAGTATAGIPHGAIIADYLKLPFAYIRSKPKDHGAGNQVEGRVAKGQKMVVVEDLISTGGSVLEAVAAAEREGADVLGVVAIFTYELEKANSKFADADVKLATLTNYSELIEIAKETGYVTKEELELLKKFKENQETWQA
>NC_009004.1|WP_011835353.1|1482281_1483553_-|dihydroorotase
MTLLIKNGRLIDPKSNRDEILDILIEENKIAKIGTNLSEENTEIIDASGLVIAPGLIDVHVHFREPGQTHKETIHSGAKSAAAGGFTTVVMMANTKPILSTPKVLTETLAIAKKEAIKIKAVASITQDFDGENLTDFAELIKAGAIGFSDDGIPLTDAGVLREALQKSKLTDSLLSIHEEDPNLIGTLGVNDGEVAHKCGFTGAPTVSEYSMMARDTMIAYETGARLHLQHLSAGESVEVVRFAKNLGAKITAEVTPQHFSITEQMIFEQGTNAKLNPPLRRDADISKIIAGLKDGTIDVIATDHAPHTHEEKNVSIDKAPSGMIGLETSLQLGLTNLVAKGHLTLLELLTKMTLNPAKLYDFDAGYLAEAGPADLVIFDAENTYQVGETFDSKATNSPFIYQKVQGQIKYTICDGNIVYQAK
>NC_009004.1|WP_011835352.1|1480956_1482024_-|SEL1-like-repeat-protein
MDKKNKHLNYEDRRKIEKLFNSNVTITEIAKEISHSRVAITNEVRRGLKKMRTSKGNIVERYYAEYAQQLYESTQSNKEKKPRFSETIKSKVKEKHQQGDSDKVIVVDIQEEFGTLAPAESTIRRWLKAFRDGQTSTIDRSYSRLGDEAYFNDDLDKATKYYEKGVQLGDTYAMTALADFYQNGKIVPQDWRKAYNLYEKAASLGDTKAMYMLSIYLDNGLGCEADSNQATFNLIKAANAGNSTGMVILASSLEHGSNLIKDLRKAVYWYRRAEEAGNVYAKKWLENHQEEVIKHLQDGVGFTDEEYLSYTWSKAHEEFGHLDKEITDKELQDLRDSGVISEISSQKPKKKKKDS
>NC_009004.1|WP_011835351.1|1476974_1480778_-|bacterial-Ig-like-domain-containing-protein
MGKYQSSHEEKQRGFRTWKSGKSWLYAASILVALAGVVGVTGASVKADSTPAPVTTSPVSTVTPFTTAPSASPAVTASTPTTDTDKGNVTNNTPTADTSASPEVTVSTPTADTDKASTTQQHVTMATPLQHKLLRATTPETSADAPSASSNLSTIYQATANITGAVSGTNLVISLSSDDGGINEPLTFTDSKSGDYSITLAKNNSSEVSNTTDIIWKDNKTGVTGTATAATDYQTNAVNIVTMRDGAPAALSYKDQTNLDVCDFYYTIGDKFDASKGFGGGTDASGNPIDFSSVKVDTSKVDLKTVGTYPVSYSVVDNTTEKTQTLVANVIVRSDPTLINLTGNNVNTNNNVNINQGATFDASQYLAYVRNLSGDSVDFSQVTVDTSHLNTAKAGVYPVYYSLPDSLITGGKYTAVLNVTVGSPLTGDASTFGVGGATVTEGDTNWAEEGSEKLLGSFWDSTGVSSATGVNSSGTKIILSGQNDKSTATYDSKAVDVNILGTYQVPITVIDPIGNSQTMYATVVVKPHDLLDGVWPDQSIQVSVPIGSNYNPMYGYPIYDDSEQQYTAVTNVNTNQEGYYQTVYAITNNSTGTDSNYKITANVRVYDDNTDGVTEQTAINAPMSSTGTVGQQWVVTDYGGNMNSISVTPSYPGESLSGFLSKYLTVSLTSKPEGSKAIAGIQAAYGDSNYGVMDCFFTPDASGSYTMTYIYTDPVSQKKVSASTVVTVPSTTTGSIDNMSISTNDVTVNQGKGLDFSNIVNSFVGADGKTVSGKDAWIWTGDDKGNIVTGDSENKVWNLTSWDPHAGAGVEDIIIDSSAVDTDKAGTYQIKYTASYDGSSKVLGTSTVTVVARDSQATLEAPKTATTAVNQPYDLTTGLMATDSTGKTINLTSGVSVAVNGKVISGTSYTPNTSGTYKIVYTNGTLSATTELIATDQSSLSAPTHHDMRTGQTYNIFTDVKALNAAGQEFSPTYQLTGQDVNGQSIDMTGLLTSANFVPKVAGIYMVTLTNGKKKATIKIAVAPSQVNSVVDEVTDNTDSAELISSTDRVLIGTVTVKKVGDTFNAYDEYVAGAAVDNNRPATTGVQATMASAIQDLLIKQYPDLATQIKSGYLNSTGILTNLVGVHIISNNVNMKKAGTYFVNYLIDSATMTFTTGDPLPAQIYDLKNMIVMRTVIVEADAVSTPNQNGGQTSKPGGGSTTTNTNSNGKTQVSMLATTYSRAKTITSASMLPITGENKSVSIVEMLLGASFISLTGLFIEMKRRKF
>NC_009004.1|WP_011835350.1|1475840_1476767_-|hypothetical-protein
MGEISSFTGVFTSMKNYIEKVIKIPFSCIVFLISIFLMFNPKLLSLIGINKWFPNQIKEIVLKIGQLFYSNMFFVSIGFVLFVLVLFGITYLPTEKIFPKDVELVNGKIKSWNSFSAFSTGINLFVLYLTTWWTYYFFINVLFNKNGFNHNFFISDKSNALYLNMTNSIIHSGYISSLNLLFMNIIFYLNIFITAYFIVQRLYQDIYILPKNSIKYNSIDTYFEYNSKVLTNSSDEETKIAILRYKHWDEAKYLLVKIPLTKNTFEWERWQQKEVWKLRKIPPAKKSIYIVLEDKELTNVIYAFDNFK
>NC_009004.1|WP_011835348.1|1472920_1475113_-|BspA-family-leucine-rich-repeat-surface-protein
MKKKLSKIQMLLLVTTLTAFSVGVVTYGPTVLNTQSITVSADTRASSGKWGEANWFLANDGELIFLGGDIGHPSQSLPEALREANVDPAAVKSIEFTTKTSANNISRAFVDLPELQKVLKLGNLNYSGSAESMFLSAANLEEIDLDGFDTSKITTMEYMFLGIKASTLDVSKFDTSNVTNMRGMFDGASNLTSLDLSSFDTSKVVDMSYLFVGLSKITELDVSSFNTSNVTNMRGMFDGVSNITSLDLSNFDTTKANDMNYMFLGAEKLEQLDISSFNTASVKSMKNMFSSMKALEKLDLTSFIISENTNSQAMFSGTNNLKNLKLGLKSQLNTGMNLENVPVTDGYTGKWQNVGSGTEDKPAGEHIWNSSEFMENFNAATMADTYVWQSLSGSEMELGEVTDYSNDKPLSDFISTATTPLNPYRYNVVLNNDHQFYSKLENGQLDTENIISLGSITGKTLYNKETVPVTYTTGDKKGQTTNFVNVSLEGDNWYWVDEHALNLDLAATYPSVNSDGIKLPDGMFLGSTITFGNNPAVSNSQMVSNAYNSQGKIIYESRAKLEDFATEAAPEAALAAFNKEIDRAVESWNAAINPNEPTIIKSSESTDSVTLVISPNPEGGGSATSIGNTGIESTLVNWALDPAAPDYDVNLLFITIRHELGHSLGLDHTSGGLYYGMPDGYRMNIDDDVMNAILSHTTGGYPWTQKTITQESIDTIHLILKNQNFSNPQH
>NC_009004.1|WP_011835347.1|1471986_1472655_-|DnaD-domain-containing-protein
MDYYDEYSKGHLVLPTVILSHFSELFPSAFDFLVWLYFFENREIAPSEIADKTGKKMSEVNQAIDSLSKFGAMKVTLIEIDGEMETFFDISPAFKHLDELVGSPALNLKAEDKKVQDEGQLKELISMFEAEMGMISPVQMEELRAWLFEDGYDLSLIKQALREAVLNRKVSLNYIKAILRNWKNDGVNSVQAIESRQMEREEAKRKKPQEDFYIPLDGPWNG
>NC_009004.1|WP_011835346.1|1471308_1471965_-|endonuclease-III
MLSKKRYLEALAIIEEMFPQAHGELVWETPFQLLIATILSAQATDKGVNKATPALFAAFPDAQAMSQAKVEEIEALIRTIGLYKTKAKNILRTSQMLVADFGGILPDLPKDKKLLQTLPGVGRKTANVVLAEAYGIPGIAVDTHVERVSKRLDIVAQKATVLEVEEKLMKLIPEDKWVQSHHHLIFFGRYHCTAKKPKCAGCPVLDYCKFGKKYLENE
>NC_009004.1|WP_011835345.1|1470626_1471316_-|tRNA-(adenine-N(1))-methyltransferase
MNEIKLSKRLKAVADYVDKGARLADIGSDHAYLPTYLVQKNEVEFAVAGEVVKGPFEIAKNHVAQANLKENIQVRLANGLAAIENVDKIDTIVIAGMGGILISEILEAGKGKLSSVKRLILQANNHGDTLRQWLIEHQFVIKAEQILLEAGKFYEIIVAEPTTNENPVLSANDLLFGPFLSKEKSVIFQQKWQKELNTLNKIIDRLPDEQTEKREEVLTEIAKIKEVLQ
>NC_009004.1|WP_011835344.1|1469856_1470630_-|Nif3-like-dinuclear-metal-center-hexameric-protein
MKISEFMSKYESFCPKELAVEGDPVGLQVGNPEQELTKVLVTLDIREQTVAEAKSLGVDLIIAKHPLIFRPLTALTSMDNQEKLVLDLAQAGIAVYTSHTNIDVVKGGLNDYFAQLLGLTDVEVLDDDEGLGRVGNIEGTDLSVLTEKVKEVFELDRLRLVTYNHDLTQKIERVAICGGSGGKLWPKALAKGADVYLTGDIYYHIGHDMLSAGLIGIDPGHYIEQKFIGLVADKLRSFGTDVKIYESQEKTNPFYDI
>NC_009004.1|WP_153951976.1|1484523_1484664_+|hypothetical-protein
MTNVTVVVVDSNKKHLPRDLASVKSIKTSSFLLTENPVSKNKISFS
>NC_009004.1|WP_011835355.1|1484826_1486734_-|ATP-binding-cassette-domain-containing-protein
MILLQGNGIARTFGGDVLFENISFSLQDQSRIALVGRNGAGKSTLLKIIAGVEEASRGTISKTKDLSMNYLAQDTGLNSQRTIFAEMLSVFDQLRQMEKQLRQMELQMGELGADELTLLMKRYDSLSEEFRMKNGFTYESEIKSVLNGFRFDESMWEREISSLSGGQKTRLALAKMLLEKPQLLILDEPTNHLDIETLAWLENYLKNYDGSLLIVSHDRYFLDKVVNEVLELSRGELTRFSGNYSRYVEQREQKLLLELKNFEKQQKEIAKLEDYVAKNLVRASTTKMAQSRRKKLEKMDRLDAPTSDDKSAHVTFTPEKTSGNVVLTVSEATVGYSDNRLSGPINIDERKGESLAIVGPNGVGKTTLIKSIVGQIPFLAGQAKLGANVTLGYYDQEQGRLTTSNTVLDELWNEHRLLNEVEIRNMLGAFLFSGDDVKKTVGMLSGGEKARLLLAKLAMNHDNFLVLDEPTNHLDIDSREVLENALIDFPGTILFVSHDRYFINRVATKVLEIAPEGSTEFLGDYDYYVEKKEEQLAQTDESDNGGLVESLAQQDFTAQKEAQKNRRKVEREITSCEEKLAELEIKIETLMLQMQENTSDFVKLGELQAEIDLLNDEKDETEMTLLEAMEELESL
>NC_009004.1|WP_011676069.1|1486906_1487299_-|transcriptional-regulator-Spx
MIKIYLSGSCSSCRKAKKWLRKRHIEFEEINLTKDIMEKDDLIKILSLTENGLEDVIATRGKTYSGLNHNFDELGLEEAYRLIQENPRLLKRPLIFDEQRLLIGFNEDGIRAFIPPEVRRVELRERLILI
>NC_009004.1|WP_011835356.1|1487521_1488172_+|redox-sensing-transcriptional-repressor-Rex
MTDHKPSKSLPKATAKRLPQYYRLFKSLVEENVTRTNSQLISEKIGVDAATIRRDFSLFGELGRRGYGYETKVLRDFFGELLGQDQETHIALIGVGNLGRALLHYQFQDRNKMRITQAYDISGNPLVGTQTDDGIPIYNISDLEKNVKKSDIKTAILSVRKENAQEVVDTLVKAGIKGFLNFAPIRLKVPSDVVVQSIDLTKELQTLLFFMGAQEE
>NC_009004.1|WP_011835357.1|1488358_1489042_-|DNA-repair-protein-RadC
MYELKEKSYPMQPRERLELLGEEYLSDVELLAILLRTGRKKYSSLNLALELLQHFGTLDNFRKASISELKEISGIGQTKAIELRAMIELGKRIQTTTRKRYGQVLSSKEYGMSLAFEMQNFEQEHLTATYLDGQNQIIEKKTIFIGAFNHATASPREILYHAVKNLSVGLLVAHNHPSGNLQPSQADKIFTKKIKNACDNIGINFIDHIIVGAGNYYSFRERDSNLF
>NC_009004.1|WP_011835358.1|1489159_1490977_-|glutamine--fructose-6-phosphate-transaminase-(isomerizing)
MCGIVGVVGSKNATDILMQGLEKLEYRGYDSAGIFVNGQKTAAKLVKSVGRIADLRAKLGIDVSGTSGIGHTRWATHGKPTEDNAHPHTSSSGRFVLVHNGVIENFVELKNEFLMNDSFKGQTDTEIAVHLIAKFAEEENLTTLEAFKKALKLIQGSYAFALMDREDADLIYVAKNKSPLLIGLGDGYNMVCSDAMAMIRETSEFMEIHDKELVVLTKDKVEVMDYEGQIISRDSYTAELDLSDIGKGTYPFYMLKEIDEQPAVMRKLIATYTNEDGTMKVDQDIIKGIQEADRIYIIAAGTSYHAGFGAKMMLEALTDTPVELGLASEWGYDMPLLSKKPFFIFLSQSGETADSRQVLVKVNELGLPSLTVTNVPGSTLSREATYTMLIGAGPEIAVASTKAYTGQIATLAFLAKAVGEAEGQAKAKDFDLVKELSLVAQSIESTLSEKDEIAAIVSELLPTTRSAFYIGRKQDYYVAMEASLKLKEISYIQCEGFAAGELKHGTISLIEKGTPVLALISNNEEVAAHTRGNVMETVARGASAITIVEEGVAREDDTIVINQVHPYLSAISMVIPTQLIAYYASMQRGLDVDKPRNLAKAVTVE
>NC_009004.1|WP_011835359.1|1491158_1491815_-|phosphatase-PAP2-family-protein
MNKKNYYILGTLTTLAFLILTVLVKIYYTHAPLPFDSPIQNWAFHLQSSSGLTFFFSHMTNIFGDKGGIIVAVLLALVLYLIFKEKKATIWFATMVISSLLINTAIKMIIGRDRPEIHRLAAFANEAGKSFPSGHSIFATIIFGSVFFICLRKLKNKSSKIALGILCLILIATVMFSRIFVGVHYPSDTIGGFLEGMSLLLFTYPTFIKYQEAAKKAN
>NC_009004.1|WP_011835360.1|1491824_1493150_-|HAMP-domain-containing-protein
MKKTESKTSANIITETFVRIFLIFTLLVTIIVSGIVAFTSLQIRESEGTSLISSVQEAAENGNVNWDEFKLDSEKDEKSTFVRLTRASGDIDESHGTSHFLKSRLSWGNFSLSKDVIFWYSSETAKNGNKVELWLNINIVVKSMIRAILVIVAVMIILFFIALILIRKAANTISQPLTDMMLATDEKEVKQLPVSKNPIEVRQLSQSFNRLLNRLNQKIENEQQFVSDASHELRTPVAAIRGHVTLLKRRWHEHPEIIDDSLSYIDEESLRMKGLIENLLTISRGNHLEVNKEKFNLTEFTDKVVSEIQPALSQKITFNGKSEIFVRADKMSLYKIIIVFIENAGKYSPQDSEIKVKISSENHQVELQVADEGVGIPEEEKINIFERFYRIDKSRSSEIPGTGLGLAIAKQYAQLNHAEVFVTNNTPKGSIFHLLMESIEN
>NC_009004.1|WP_011835361.1|1493153_1493669_-|DUF2127-domain-containing-protein
MEKVKNKEELLDVSFNAMLLGKSIFAFVEFLSGLLLIFIPLDLIKSTIQHLAASIAFAPLSSMITNAGERLTSDATLFAVIYLLLHGALKLVTLALLWRKILWSYPLSIVLLVGFITYQMFEFFNHGAISMLVLCVVDLVMIALTLLEYRKLKVQLSKGQSYSSLKNIKIN
>NC_009004.1|WP_011835362.1|1493689_1494376_-|response-regulator-transcription-factor
MTYHVLIVEDEPSISDYVKKELVFEDYQVSTAFDGLAALEVFEQAKPAVDVVLLDWMIPKLDGLTVLRRMKKIQPNTPIIFLTARDYIGDKVAGLDAGADDYITKPFEIEELLARLRLIFRKWSTSRSKVYELDYLKVDLTAHTTEVAGKTVNLTQREFALLSYFLEHRGIVVSRADILDDVWGMDFDGQENTVDAYVRYLRATIDLPNHKSLIETVRGVGYRLNGEG

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

32973 : 85063

Lactococcus_phage(70.97%)

tRNA,transposase,bacteriocin,integrase

attL 32370:32394|attR 51759:51783

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
32370:32394	attL	NA	NA	NA	NA
WP_011834138.1\|32973_33297_-	sigma-70 family RNA polymerase sigma factor	Q9AZI1	Lactococcus_phage	1.2e-42	82.2
WP_041931235.1\|33397_33730_-	hypothetical protein	Q9AZE0	Lactococcus_phage	3.4e-40	75.0
WP_011834140.1\|33805_34108_-	hypothetical protein	NA	NA	NA	NA
WP_011834141.1\|34424_35006_-	hypothetical protein	Q9AZI4	Lactococcus_phage	7.0e-89	89.6
WP_011834142.1\|35241_36870_-	DNA primase	Q9AZI5	Lactococcus_phage	0.0e+00	98.5
WP_011834143.1\|36880_37675_-	bifunctional DNA primase/polymerase	Q9AZI6	Lactococcus_phage	2.8e-144	91.7
WP_011834144.1\|37671_38007_-	hypothetical protein	Q9AZI7	Lactococcus_phage	4.2e-54	95.4
WP_011834146.1\|38254_38494_-	hypothetical protein	Q9AZJ0	Lactococcus_phage	2.2e-36	92.4
WP_011834147.1\|38535_38817_-	hypothetical protein	Q9AZJ1	Lactococcus_phage	1.2e-46	95.7
WP_011834148.1\|38828_39254_-	hypothetical protein	Q9AZF1	Lactococcus_phage	2.8e-71	92.2
WP_011834149.1\|39258_39453_-	DUF1655 domain-containing protein	Q9AZF2	Lactococcus_phage	5.7e-27	93.8
WP_011834150.1\|39568_39754_-	helix-turn-helix transcriptional regulator	A0A1X9I6I3	Streptococcus_phage	1.2e-05	42.6
WP_011834151.1\|39836_40163_+	hypothetical protein	NA	NA	NA	NA
WP_011834152.1\|40518_40734_-	hypothetical protein	NA	NA	NA	NA
WP_041931236.1\|40889_41282_+	helix-turn-helix domain-containing protein	A5GZ65	Lactococcus_phage	1.4e-37	60.9
WP_011834154.1\|41311_41866_+	hypothetical protein	Q9AZJ8	Lactococcus_phage	2.4e-102	92.4
WP_011834155.1\|41976_42207_+	hypothetical protein	Q9AZK0	Lactococcus_phage	1.2e-15	85.5
WP_011834156.1\|42279_42474_+	hypothetical protein	Q9AZK1	Lactococcus_phage	1.0e-28	98.4
WP_014734881.1\|42726_42984_+	hypothetical protein	NA	NA	NA	NA
WP_011834157.1\|43097_44423_+	DNA/RNA non-specific endonuclease	NA	NA	NA	NA
WP_011834158.1\|44504_44711_+	hypothetical protein	Q9AZK3	Lactococcus_phage	6.7e-18	64.7
WP_011834159.1\|45200_45443_+	hypothetical protein	Q9AZK2	Lactococcus_phage	5.1e-33	98.8
WP_010905058.1\|45578_45803_+	hypothetical protein	Q9AZK3	Lactococcus_phage	4.5e-36	100.0
WP_003331415.1\|46466_47690_+\|transposase	IS21-like element IS712 family transposase	A0A059NT83	Lactococcus_phage	4.9e-233	100.0
WP_003331414.1\|47701_48460_+	ATP-binding protein	A0A059NT77	Lactococcus_phage	5.3e-137	100.0
WP_011834160.1\|48561_48888_+	hypothetical protein	NA	NA	NA	NA
WP_010905061.1\|49621_49786_+\|bacteriocin	bacteriocin	Q9AZK6	Lactococcus_phage	7.9e-22	100.0
WP_010905062.1\|49907_50213_+\|bacteriocin	bacteriocin immunity protein	Q9AZK7	Lactococcus_phage	8.3e-49	100.0
WP_011834162.1\|50462_51647_+\|integrase	site-specific integrase	Q9AZK8	Lactococcus_phage	3.6e-225	99.5
WP_014734884.1\|52155_52869_-	alpha/beta hydrolase	NA	NA	NA	NA
51759:51783	attR	NA	NA	NA	NA
WP_011834164.1\|53630_53996_+	hypothetical protein	NA	NA	NA	NA
WP_011834165.1\|54400_54892_+	hypothetical protein	A0A1S5SAH9	Streptococcus_phage	2.4e-05	27.7
WP_014734885.1\|54929_55283_+	DUF1648 domain-containing protein	NA	NA	NA	NA
WP_011675106.1\|55404_55563_+	hypothetical protein	NA	NA	NA	NA
WP_041931237.1\|56003_56453_+	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_050750505.1\|56531_56777_+	TM2 domain-containing protein	NA	NA	NA	NA
WP_011834168.1\|56869_58492_-	SulP family inorganic anion transporter	NA	NA	NA	NA
WP_003138385.1\|58701_59877_-\|transposase	IS256-like element IS905 family transposase	A0A0N9STL0	Staphylococcus_phage	2.5e-32	32.3
WP_011834169.1\|60022_60544_+	N-acetyltransferase	A0A1P8CWJ6	Bacillus_phage	6.0e-31	42.1
WP_011834170.1\|60872_62048_+	pyridoxal phosphate-dependent aminotransferase	NA	NA	NA	NA
WP_011834171.1\|62145_62901_+	DNA repair protein RecO	NA	NA	NA	NA
WP_011834172.1\|63014_63896_+	Rgg/GadR/MutR family transcriptional regulator	NA	NA	NA	NA
WP_011834173.1\|64006_65242_+	MFS transporter	NA	NA	NA	NA
WP_011834174.1\|65272_66691_-	dihydrolipoyl dehydrogenase	A0A2K5B2C5	Erysipelothrix_phage	1.0e-40	27.2
WP_011834175.1\|66909_68502_-	2-oxo acid dehydrogenase subunit E2	NA	NA	NA	NA
WP_011834176.1\|68494_69475_-	alpha-ketoacid dehydrogenase subunit beta	NA	NA	NA	NA
WP_011834177.1\|69477_70602_-	thiamine pyrophosphate-dependent dehydrogenase E1 component subunit alpha	NA	NA	NA	NA
WP_011834178.1\|70690_71692_-	lipoate--protein ligase	NA	NA	NA	NA
WP_011834179.1\|71884_72739_-	glycerophosphodiester phosphodiesterase	A0A0S2MYI4	Enterococcus_phage	1.7e-11	30.4
WP_011834180.1\|72817_73468_-	HD domain-containing protein	A0A1S5XYU7	Kurlavirus	2.0e-15	32.9
WP_011834181.1\|73517_73844_-	hypothetical protein	NA	NA	NA	NA
WP_011834182.1\|73936_74962_-\|tRNA	tryptophan--tRNA ligase	NA	NA	NA	NA
WP_011834183.1\|75460_75898_+	OsmC family protein	NA	NA	NA	NA
WP_011834184.1\|76059_77373_+	APC family permease	NA	NA	NA	NA
WP_011834185.1\|77432_77783_+	hypothetical protein	NA	NA	NA	NA
WP_011834186.1\|77842_78838_-	phosphate acyltransferase PlsX	NA	NA	NA	NA
WP_011834187.1\|78940_79753_-	HAD family hydrolase	NA	NA	NA	NA
WP_011834188.1\|80128_81766_-	ATP-binding cassette domain-containing protein	A0A2K9L3Z8	Tupanvirus	5.3e-49	25.7
WP_011834189.1\|82265_82520_+	hypothetical protein	NA	NA	NA	NA
WP_011834190.1\|82639_83464_-	SDR family NAD(P)-dependent oxidoreductase	NA	NA	NA	NA
WP_164845598.1\|83679_85063_+\|transposase	IS3 family transposase	A0A1B1P773	Bacillus_phage	1.1e-55	41.8

DBSCAN-SWA_2

400610 : 412766

Streptococcus_phage(30.0%)

tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_011675460.1\|400610_400928_+	thioredoxin family protein	A0A0K2FIM3	Achromobacter_phage	9.0e-06	31.9
WP_011834456.1\|401033_401660_+\|tRNA	DUF4479 and tRNA-binding domain-containing protein	NA	NA	NA	NA
WP_011834457.1\|401821_403162_+	FAD-dependent oxidoreductase	NA	NA	NA	NA
WP_011834458.1\|403252_403642_+	single-stranded DNA-binding protein	A0A2I2MUI5	uncultured_Caudovirales_phage	2.0e-23	42.3
WP_011834459.1\|403760_404045_+	co-chaperone GroES	A0A221S386	uncultured_virus	1.1e-13	44.1
WP_011834460.1\|404131_405760_+	chaperonin GroEL	A0A219YK78	uncultured_virus	5.5e-155	56.4
WP_011675466.1\|405809_406622_-	MBL fold metallo-hydrolase	A0A0C5AJ83	Bacteriophage	1.5e-33	38.1
WP_173249647.1\|406812_408168_-	cell wall metabolism sensor histidine kinase WalK	W8CYF6	Bacillus_phage	1.4e-31	32.9
WP_003131580.1\|408232_408934_-	response regulator transcription factor	W8CYM9	Bacillus_phage	1.2e-42	39.7
WP_011834462.1\|409111_409747_+	dTMP kinase	M1PSC7	Streptococcus_phage	4.5e-73	65.5
WP_011834463.1\|409879_410740_+	DNA polymerase III subunit delta'	M1NSC1	Streptococcus_phage	1.1e-64	45.2
WP_011834464.1\|410789_411572_+	stage 0 sporulation family protein	NA	NA	NA	NA
WP_011834465.1\|411564_411891_+	DNA replication initiation control protein YabA	NA	NA	NA	NA
WP_011834466.1\|411890_412766_+	16S rRNA (cytidine(1402)-2'-O)-methyltransferase	M1PLC5	Streptococcus_phage	7.1e-101	66.4

DBSCAN-SWA_3

579633 : 634046

Lactococcus_phage(35.0%)

tRNA,protease,transposase,integrase

attL 607384:607443|attR 612848:612955

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_011675765.1\|579633_580299_+	YitT family protein	M1Q1P6	Streptococcus_phage	2.3e-19	29.8
WP_011834608.1\|580429_581314_+\|tRNA	tRNA (adenosine(37)-N6)-dimethylallyltransferase MiaA	NA	NA	NA	NA
WP_011834609.1\|581459_582128_+	hypothetical protein	NA	NA	NA	NA
WP_011675768.1\|582292_583195_+	SPFH domain-containing protein	A0A1V0SL90	Klosneuvirus	1.8e-35	35.2
WP_011834610.1\|583443_584460_-\|integrase	site-specific integrase	Q9AZR0	Lactococcus_phage	4.0e-71	42.9
WP_011834611.1\|584680_585172_-	hypothetical protein	Q9AZF8	Lactococcus_phage	3.6e-78	93.3
WP_011834612.1\|585447_585657_-	hypothetical protein	Q9AZF6	Lactococcus_phage	2.3e-26	83.6
WP_162466999.1\|585724_586003_-	hypothetical protein	Q9AZW4	Lactococcus_phage	5.5e-23	69.6
WP_162467000.1\|585941_586232_-	hypothetical protein	Q9G0E8	Lactococcus_phage	1.2e-12	81.8
WP_014734944.1\|586212_586389_-	hypothetical protein	NA	NA	NA	NA
WP_011834615.1\|586682_588290_+	glycosyltransferase family 39 protein	NA	NA	NA	NA
WP_161769936.1\|588213_589146_+	glycosyltransferase family 2 protein	V9QJB1	Oenococcus_phage	6.6e-81	49.7
WP_011834617.1\|589411_589903_-	hypothetical protein	NA	NA	NA	NA
WP_011834618.1\|589915_590290_-	PH domain-containing protein	A5GYQ0	Lactococcus_phage	7.1e-50	80.6
WP_011834619.1\|590634_590982_-	XRE family transcriptional regulator	A0A182BQC8	Lactococcus_phage	3.1e-44	76.3
WP_011834620.1\|591747_592671_+	ribonuclease Z	NA	NA	NA	NA
WP_014734945.1\|592663_593365_+	SDR family NAD(P)-dependent oxidoreductase	NA	NA	NA	NA
WP_011834622.1\|593537_595766_+	single-stranded-DNA-specific exonuclease RecJ	A7KV88	Bacillus_phage	2.3e-79	31.3
WP_011834623.1\|595889_596402_+	adenine phosphoribosyltransferase	A0A1V0SKE5	Klosneuvirus	5.3e-32	44.0
WP_011834624.1\|596617_597184_+	DNA-directed RNA polymerase subunit delta	NA	NA	NA	NA
WP_041931175.1\|597319_598960_+	endolytic transglycosylase MltG	NA	NA	NA	NA
WP_011834626.1\|599020_599491_+	transcription elongation factor GreA	NA	NA	NA	NA
WP_101928132.1\|601030_602177_+\|transposase	IS3 family transposase	U5P429	Shigella_phage	2.3e-46	41.0
WP_011834627.1\|602408_602864_+	CtsR family transcriptional regulator	NA	NA	NA	NA
WP_011834628.1\|602853_605304_+\|protease	ATP-dependent Clp protease ATP-binding subunit	A0A223W0B1	Agrobacterium_phage	2.4e-122	33.9
WP_011834629.1\|605438_605996_+	ribosome-associated translation inhibitor RaiA	NA	NA	NA	NA
WP_010905473.1\|606183_607485_+	phosphopyruvate hydratase	A0A1X9I5Z8	Streptococcus_phage	4.0e-217	87.6
607384:607443	attL	NA	NA	NA	NA
WP_011834630.1\|607573_608509_+\|integrase	tyrosine-type recombinase/integrase	A0A142F1N9	Bacillus_phage	4.0e-25	27.5
WP_011834631.1\|608635_609268_+	hypothetical protein	NA	NA	NA	NA
WP_102032783.1\|610647_611759_-\|transposase	IS3-like element IS981 family transposase	A0A1P8CWQ3	Bacillus_phage	4.7e-49	41.4
WP_011834633.1\|611838_612519_+	abortive infection protein	NA	NA	NA	NA
WP_011834634.1\|613052_613724_-	ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	1.9e-29	36.8
612848:612955	attR	NA	NA	NA	NA
WP_011834635.1\|613725_614799_-	ABC transporter permease	NA	NA	NA	NA
WP_011834636.1\|614810_615380_-	TetR/AcrR family transcriptional regulator	NA	NA	NA	NA
WP_011834637.1\|615569_617093_-	acyl-CoA synthetase	NA	NA	NA	NA
WP_011834638.1\|617286_618204_+	magnesium transporter CorA family protein	NA	NA	NA	NA
WP_011834639.1\|618463_620827_+	formate C-acetyltransferase	A0A2P0VNR5	Tetraselmis_virus	4.7e-107	31.6
WP_011834640.1\|620955_621615_+	dephospho-CoA kinase	NA	NA	NA	NA
WP_011834641.1\|621617_622835_+	multidrug efflux MFS transporter	NA	NA	NA	NA
WP_003129585.1\|622831_622978_+	50S ribosomal protein L33	NA	NA	NA	NA
WP_011834642.1\|623354_624617_+	FtsW/RodA/SpoVE family cell cycle protein	NA	NA	NA	NA
WP_011834643.1\|624721_628135_+	pyruvate carboxylase	NA	NA	NA	NA
WP_011834644.1\|628260_629586_+	citrate/2-methylcitrate synthase	NA	NA	NA	NA
WP_011834645.1\|629582_632129_+	aconitate hydratase AcnA	NA	NA	NA	NA
WP_011834646.1\|632148_633387_+	NADP-dependent isocitrate dehydrogenase	NA	NA	NA	NA
WP_011834647.1\|633446_634046_-\|protease	ATP-dependent Clp protease proteolytic subunit	A0A223W000	Agrobacterium_phage	7.1e-52	52.6

DBSCAN-SWA_4

643148 : 699801

Staphylococcus_phage(16.67%)

transposase,bacteriocin

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_102032784.1\|643148_644260_-\|transposase	IS3-like element IS981 family transposase	A0A1P8CWQ3	Bacillus_phage	2.8e-49	41.4
WP_102032798.1\|644314_645115_+	polysaccharide deacetylase family protein	NA	NA	NA	NA
WP_011834657.1\|645201_646551_-	branched-chain amino acid transport system II carrier protein	NA	NA	NA	NA
WP_011834658.1\|646766_647039_-	N-acetyltransferase	NA	NA	NA	NA
WP_011834662.1\|649641_650532_-\|transposase	IS982-like element ISLla2 family transposase	NA	NA	NA	NA
WP_041931256.1\|650981_654059_+	type I restriction endonuclease subunit R	NA	NA	NA	NA
WP_014734957.1\|654058_655678_+	type I restriction-modification system subunit M	A0A2H4PQP4	Staphylococcus_phage	3.2e-123	49.7
WP_063283236.1\|656261_656894_+	restriction endonuclease subunit S	A0A2H4PQP5	Staphylococcus_phage	8.1e-14	29.6
WP_003131454.1\|657079_658030_+	magnesium transporter CorA family protein	NA	NA	NA	NA
WP_011834666.1\|659930_660578_+	pyroglutamyl-peptidase I	NA	NA	NA	NA
WP_011834667.1\|660768_661965_-	amidohydrolase	NA	NA	NA	NA
WP_011834668.1\|663029_664286_+	OFA family MFS transporter	NA	NA	NA	NA
WP_101812836.1\|664403_664547_-\|transposase	IS3 family transposase	NA	NA	NA	NA
WP_011834669.1\|665113_665431_+	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_011834671.1\|665907_666210_-	hypothetical protein	NA	NA	NA	NA
WP_011834672.1\|666206_666383_-\|bacteriocin	lactococcin family bacteriocin	NA	NA	NA	NA
WP_101913470.1\|666519_666747_-	hypothetical protein	NA	NA	NA	NA
WP_011834674.1\|666945_667563_-	hypothetical protein	NA	NA	NA	NA
WP_011834675.1\|667839_668520_-\|transposase	IS6 family transposase	A0A1X9I6C6	Streptococcus_phage	4.2e-109	82.7
WP_011834676.1\|668848_669088_+	hypothetical protein	NA	NA	NA	NA
WP_011834677.1\|669247_669745_-	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_011834678.1\|670032_670245_+	hypothetical protein	NA	NA	NA	NA
WP_011834679.1\|671498_671690_+	hypothetical protein	NA	NA	NA	NA
WP_003140242.1\|671741_671918_+	hypothetical protein	NA	NA	NA	NA
WP_011834680.1\|672064_672550_+	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_003331415.1\|672798_674022_+\|transposase	IS21-like element IS712 family transposase	A0A059NT83	Lactococcus_phage	4.9e-233	100.0
WP_003331414.1\|674033_674792_+	ATP-binding protein	A0A059NT77	Lactococcus_phage	5.3e-137	100.0
WP_011834681.1\|676554_676701_+	hypothetical protein	NA	NA	NA	NA
WP_011834682.1\|677107_677389_+	hypothetical protein	NA	NA	NA	NA
WP_011834683.1\|677972_678140_+\|bacteriocin	lactococcin family bacteriocin	NA	NA	NA	NA
WP_011834671.1\|678146_678449_+	hypothetical protein	NA	NA	NA	NA
WP_011834685.1\|678700_680563_+	heavy metal translocating P-type ATPase	E4ZFI9	Streptococcus_phage	4.7e-102	36.0
WP_011834687.1\|681268_681496_+	heavy-metal-associated domain-containing protein	NA	NA	NA	NA
WP_031297113.1\|681544_682090_+	DNA-binding protein	NA	NA	NA	NA
WP_011834689.1\|682175_682865_+	Crp/Fnr family transcriptional regulator	NA	NA	NA	NA
WP_011834692.1\|683541_684558_+	murein tripeptide/oligopeptide ABC transporter ATP binding protein OppD	G9BWD6	Planktothrix_phage	3.8e-21	32.3
WP_010906164.1\|684554_685514_+	murein tripeptide/oligopeptide ABC transporter ATP binding protein OppF	G3M9Y6	Bacillus_virus	1.6e-13	31.1
WP_010906163.1\|685494_686454_+	murein tripeptide/oligopeptide ABC transporter permease OppB	NA	NA	NA	NA
WP_003140250.1\|686463_687348_+	murein tripeptide/oligopeptide ABC transporter permease OppC	NA	NA	NA	NA
WP_011834693.1\|687457_689260_+	oligopeptide ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_011834694.1\|689384_691268_+	endopeptidase PepO	E3T4I7	Cafeteria_roenbergensis_virus	1.8e-72	31.1
WP_011834695.1\|691570_692890_+\|transposase	IS4-like element IS1675 family transposase	NA	NA	NA	NA
WP_011834696.1\|693317_693521_+\|bacteriocin	lactococcin family bacteriocin	NA	NA	NA	NA
WP_011834697.1\|693513_693837_+\|bacteriocin	bacteriocin immunity protein	NA	NA	NA	NA
WP_011834698.1\|694245_694527_+\|bacteriocin	bacteriocin immunity protein	NA	NA	NA	NA
WP_010890674.1\|694697_695000_-	hypothetical protein	NA	NA	NA	NA
WP_011834700.1\|694992_695268_-	DUF2089 family protein	NA	NA	NA	NA
WP_041931261.1\|695524_695842_+	PadR family transcriptional regulator	NA	NA	NA	NA
WP_011834702.1\|695838_696666_+	hypothetical protein	NA	NA	NA	NA
WP_011834703.1\|696900_697455_+	recombinase family protein	A0A286S1P7	Klebsiella_phage	1.8e-41	49.7
WP_011834704.1\|697798_698404_-	AbiV family abortive infection protein	NA	NA	NA	NA
WP_102032785.1\|698692_699801_-\|transposase	IS3 family transposase	U5P429	Shigella_phage	3.3e-34	36.5

DBSCAN-SWA_5

775432 : 821910

Lactococcus_phage(98.31%)

transposase,head,protease,capsid,portal,terminase,bacteriocin,integrase,holin,tail

attL 766402:766418|attR 820943:820959

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
766402:766418	attL	NA	NA	NA	NA
WP_014734979.1\|775432_776911_+	sugar ABC transporter ATP-binding protein	A0A2H4PQG7	Staphylococcus_phage	5.9e-15	30.1
WP_041168731.1\|776913_777855_+	sugar ABC transporter permease	NA	NA	NA	NA
WP_011834767.1\|777866_778841_+	substrate-binding domain-containing protein	NA	NA	NA	NA
WP_011834768.1\|779031_780165_-\|integrase	site-specific integrase	A0A059NT56	Lactococcus_phage	1.2e-204	100.0
WP_011834769.1\|780290_780917_-	DUF308 domain-containing protein	A0A059NT54	Lactococcus_phage	1.2e-70	100.0
WP_011834770.1\|780973_781411_-	ImmA/IrrE family metallo-endopeptidase	A0A059NT76	Lactococcus_phage	6.3e-82	100.0
WP_011834771.1\|781407_781905_-	helix-turn-helix transcriptional regulator	A0A059NT51	Lactococcus_phage	2.2e-83	100.0
WP_011834772.1\|782306_783116_-	TIGR02391 family protein	A0A059NT45	Lactococcus_phage	2.8e-152	100.0
WP_003129361.1\|783269_783521_+	helix-turn-helix transcriptional regulator	A0A059NT65	Lactococcus_phage	1.9e-38	100.0
WP_011834773.1\|783535_783754_+	hypothetical protein	A0A059NT62	Lactococcus_phage	8.6e-32	100.0
WP_011834774.1\|783763_784477_+	phage antirepressor Ant	A0A059NT90	Lactococcus_phage	7.0e-131	100.0
WP_011834775.1\|784489_784726_+	helix-turn-helix domain-containing protein	A0A059NT59	Lactococcus_phage	4.3e-37	100.0
WP_011834776.1\|784879_785113_+	hypothetical protein	A0A059NT46	Lactococcus_phage	1.8e-35	100.0
WP_011834777.1\|785067_785346_-	hypothetical protein	A0A059NT68	Lactococcus_phage	1.1e-47	100.0
WP_002819828.1\|785451_785700_+	hypothetical protein	A0A059NT64	Lactococcus_phage	1.0e-36	100.0
WP_011834778.1\|785696_785873_+	putative transcriptional regulator	A0A059NT92	Lactococcus_phage	2.2e-25	100.0
WP_011834779.1\|785977_786496_+	host-nuclease inhibitor Gam family protein	A0A059NT60	Lactococcus_phage	6.9e-88	100.0
WP_011834780.1\|786504_787224_+	AAA family ATPase	A0A059NT47	Lactococcus_phage	4.4e-133	100.0
WP_011834781.1\|787223_787727_+	hypothetical protein	A0A059NT72	Lactococcus_phage	9.1e-93	100.0
WP_011834782.1\|787862_788702_+	phage replisome organiser protein	A0A059NT67	Lactococcus_phage	1.1e-132	100.0
WP_011834783.1\|788711_789596_+	ATP-binding protein	A0A059NT94	Lactococcus_phage	1.6e-164	100.0
WP_011834784.1\|789592_789757_+	hypothetical protein	A0A059NT61	Lactococcus_phage	1.9e-23	100.0
WP_014734980.1\|789746_790166_+	hypothetical protein	A0A059NT48	Lactococcus_phage	4.6e-74	100.0
WP_011834786.1\|790166_790406_+	DUF1031 domain-containing protein	A0A059NT75	Lactococcus_phage	1.4e-38	100.0
WP_011834787.1\|790511_791036_+	hypothetical protein	A0A059NT70	Lactococcus_phage	5.5e-93	100.0
WP_011676933.1\|791049_791256_+	DUF1125 domain-containing protein	A0A1P8BL00	Lactococcus_phage	2.4e-31	100.0
WP_011834788.1\|791248_791797_+	DUF1642 domain-containing protein	A0A059NT63	Lactococcus_phage	2.2e-100	100.0
WP_011834789.1\|791793_792213_+	dUTP diphosphatase	A0A059NT49	Lactococcus_phage	3.9e-73	100.0
WP_011834790.1\|792215_792554_+	hypothetical protein	A0A059NT79	Lactococcus_phage	8.6e-55	100.0
WP_011834791.1\|792550_793231_+	hypothetical protein	A0A059NT73	Lactococcus_phage	1.3e-129	100.0
WP_011834792.1\|793310_793529_+	hypothetical protein	A0A059NT96	Lactococcus_phage	2.9e-35	100.0
WP_011834793.1\|793525_793699_+	DUF1660 domain-containing protein	A0A059NT66	Lactococcus_phage	6.4e-30	100.0
WP_003131928.1\|794053_794479_+	DUF722 domain-containing protein	A0A059NT50	Lactococcus_phage	1.3e-76	100.0
WP_003331415.1\|794655_795879_+\|transposase	IS21-like element IS712 family transposase	A0A059NT83	Lactococcus_phage	4.9e-233	100.0
WP_003331414.1\|795890_796649_+	ATP-binding protein	A0A059NT77	Lactococcus_phage	5.3e-137	100.0
WP_011834794.1\|797029_797542_+\|terminase	terminase small subunit	A0A059NT97	Lactococcus_phage	6.0e-84	100.0
WP_011834795.1\|797531_798767_+\|terminase	PBSX family phage terminase large subunit	A0A059NT69	Lactococcus_phage	2.6e-242	100.0
WP_011834796.1\|798776_800285_+\|portal	phage portal protein	A0A059NT52	Lactococcus_phage	3.9e-264	100.0
WP_014734981.1\|800241_800406_+	hypothetical protein	NA	NA	NA	NA
WP_102032787.1\|800435_800678_+	hypothetical protein	NA	NA	NA	NA
WP_011834797.1\|800674_800962_+\|protease	ribosomal-processing cysteine protease Prp	A0A059NT85	Lactococcus_phage	1.7e-48	100.0
WP_011834798.1\|800967_802065_+\|capsid	minor capsid protein	A0A059NT80	Lactococcus_phage	4.3e-204	100.0
WP_011834799.1\|802097_802628_+	hypothetical protein	A0A059NT98	Lactococcus_phage	4.9e-97	100.0
WP_011834800.1\|802687_802846_+	hypothetical protein	A0A059NT71	Lactococcus_phage	2.6e-22	100.0
WP_011834801.1\|802842_803115_-	DUF3892 domain-containing protein	A0A059NT53	Lactococcus_phage	1.4e-39	100.0
WP_011834802.1\|803291_803918_+	DUF4355 domain-containing protein	A0A059NT87	Lactococcus_phage	2.7e-78	100.0
WP_011834803.1\|803929_805048_+	Ig-like domain-containing protein	A0A059NT82	Lactococcus_phage	1.1e-175	100.0
WP_011834804.1\|805068_805401_+\|head,tail	phage head-tail connector protein	A0A059NT99	Lactococcus_phage	1.3e-55	100.0
WP_011834805.1\|805381_805735_+	hypothetical protein	A0A059NT74	Lactococcus_phage	4.9e-61	100.0
WP_011676912.1\|805718_806267_+	hypothetical protein	A0A059NT55	Lactococcus_phage	6.0e-98	100.0
WP_011834806.1\|806266_806629_+	hypothetical protein	A0A059NT89	Lactococcus_phage	1.0e-61	100.0
WP_011834807.1\|806641_807055_+\|tail	major tail protein	A0A059NT84	Lactococcus_phage	1.6e-71	100.0
WP_011834808.1\|807131_807542_+	hypothetical protein	A0A059NTA0	Lactococcus_phage	1.3e-68	100.0
WP_014734984.1\|807565_807937_+	hypothetical protein	A0A059NT78	Lactococcus_phage	1.1e-47	100.0
WP_011834810.1\|807968_812669_+\|tail	tail protein	A0A059NT57	Lactococcus_phage	0.0e+00	100.0
WP_011834811.1\|812680_813046_+	hypothetical protein	A0A059NT91	Lactococcus_phage	1.4e-63	100.0
WP_011834812.1\|813057_815595_+	hypothetical protein	A0A059NT86	Lactococcus_phage	0.0e+00	100.0
WP_011676905.1\|815591_815729_+	hypothetical protein	NA	NA	NA	NA
WP_011834813.1\|815728_817222_+	hypothetical protein	A0A059NTA1	Lactococcus_phage	2.2e-280	100.0
WP_011834814.1\|817302_817608_+	hypothetical protein	A0A059NT81	Lactococcus_phage	2.8e-52	100.0
WP_011834815.1\|817594_817819_+\|holin	holin	A0A059NT58	Lactococcus_phage	1.1e-34	100.0
WP_011834816.1\|817815_819105_+	LysM peptidoglycan-binding domain-containing protein	A0A059NT93	Lactococcus_phage	3.3e-248	100.0
WP_011834817.1\|819286_820246_+	Abi family protein	A0A059NT88	Lactococcus_phage	2.2e-180	100.0
WP_173249648.1\|820517_820673_+\|holin	bacteriophage holin	A0A059NTA2	Lactococcus_phage	2.2e-21	98.0
WP_011834819.1\|821177_821600_+\|bacteriocin	garvicin Q family class II bacteriocin	NA	NA	NA	NA
820943:820959	attR	NA	NA	NA	NA
WP_011834820.1\|821604_821910_+\|bacteriocin	bacteriocin immunity protein	NA	NA	NA	NA

DBSCAN-SWA_6

945824 : 954765

Synechococcus_phage(33.33%)

transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_102032788.1\|945824_947217_+\|transposase	IS3 family transposase	A0A1B1P773	Bacillus_phage	5.9e-57	45.0
WP_011834921.1\|947598_948405_+	hypothetical protein	A0A1P8BMN5	Lactococcus_phage	2.2e-11	47.6
WP_011834922.1\|948592_951196_+	ATP-dependent chaperone ClpB	K4FB40	Cronobacter_phage	1.4e-123	32.7
WP_011834923.1\|951379_952402_+	phosphoribosylformylglycinamidine cyclo-ligase	A0A0E3F760	Synechococcus_phage	2.4e-60	41.5
WP_011676469.1\|952430_952979_+	phosphoribosylglycinamide formyltransferase	M4QRX9	Synechococcus_phage	1.5e-19	32.0
WP_014734995.1\|953169_954765_+	ABC transporter ATP-binding protein	F2Y1V6	Organic_Lake_phycodnavirus	6.6e-12	34.1

DBSCAN-SWA_7

1026183 : 1034978

Bacillus_phage(33.33%)

transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_011834981.1\|1026183_1027737_-	two-component sensor histidine kinase	W8CYF6	Bacillus_phage	3.5e-34	37.8
WP_011676390.1\|1027726_1028437_-	response regulator transcription factor	A0A1V0SGR9	Hokovirus	5.3e-06	30.1
WP_011676389.1\|1028620_1028956_+	putative DNA-binding protein	NA	NA	NA	NA
WP_011834982.1\|1029742_1030273_+	hypothetical protein	NA	NA	NA	NA
WP_164845598.1\|1030383_1031767_+\|transposase	IS3 family transposase	A0A1B1P773	Bacillus_phage	1.1e-55	41.8
WP_102032790.1\|1031841_1032943_+\|transposase	IS3 family transposase	U5P429	Shigella_phage	1.7e-38	40.4
WP_003331414.1\|1032984_1033743_-	ATP-binding protein	A0A059NT77	Lactococcus_phage	5.3e-137	100.0
WP_011834984.1\|1033754_1034978_-\|transposase	IS21-like element IS712 family transposase	A0A059NT83	Lactococcus_phage	2.4e-232	99.8

DBSCAN-SWA_8

1224963 : 1231444

Lactococcus_phage(83.33%)

transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_011835138.1\|1224963_1225821_+	aldo/keto reductase	A0A1V0SKP9	Klosneuvirus	1.2e-28	30.6
WP_011835139.1\|1226568_1226769_+	hypothetical protein	Q9AZK6	Lactococcus_phage	2.6e-06	55.8
WP_003132324.1\|1226899_1227100_+	cold shock domain-containing protein	Q9AZD3	Lactococcus_phage	8.2e-13	50.8
WP_011835124.1\|1227377_1227578_+	cold-shock protein	Q9AZD3	Lactococcus_phage	2.4e-28	93.9
WP_011835140.1\|1228093_1228333_+	GlsB/YeaQ/YmgE family stress response membrane protein	NA	NA	NA	NA
WP_011835141.1\|1228362_1228923_+	alkaline shock response membrane anchor protein AmaP	NA	NA	NA	NA
WP_011835142.1\|1228932_1229121_+	DUF2273 domain-containing protein	NA	NA	NA	NA
WP_011835143.1\|1229141_1229402_+	Asp23/Gls24 family envelope stress response protein	NA	NA	NA	NA
WP_003331414.1\|1229450_1230209_-	ATP-binding protein	A0A059NT77	Lactococcus_phage	5.3e-137	100.0
WP_003331415.1\|1230220_1231444_-\|transposase	IS21-like element IS712 family transposase	A0A059NT83	Lactococcus_phage	4.9e-233	100.0

DBSCAN-SWA_9

1505889 : 1519571

Bacillus_virus(25.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_011835376.1\|1505889_1508364_-	DNA topoisomerase IV subunit A	G3M9Z5	Bacillus_virus	1.8e-96	31.8
WP_011835377.1\|1508688_1509138_-	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_011835378.1\|1509134_1509968_-	3'-5' exonuclease	A0A0K2SUJ2	Clostridium_phage	1.2e-20	39.4
WP_014735065.1\|1509960_1510497_-	cysteine hydrolase	NA	NA	NA	NA
WP_011835380.1\|1510603_1512538_-	DNA topoisomerase IV subunit B	G3M9Z3	Bacillus_virus	5.4e-125	43.2
WP_011835381.1\|1512816_1513458_+	glycerol-3-phosphate 1-O-acyltransferase PlsY	NA	NA	NA	NA
WP_011675987.1\|1513631_1513850_+	redoxin NrdH	C3U2K9	Lactococcus_phage	5.8e-12	47.6
WP_011835382.1\|1513851_1514274_+	class Ib ribonucleoside-diphosphate reductase assembly flavoprotein NrdI	A0A142F1R4	Bacillus_phage	2.3e-12	36.4
WP_011835383.1\|1514410_1516579_+	class 1b ribonucleoside-diphosphate reductase subunit alpha	A8E2R1	Enterococcus_phage	5.6e-256	60.7
WP_011675984.1\|1516863_1517841_+	class 1b ribonucleoside-diphosphate reductase subunit beta	A0A096XT60	Enterococcus_phage	6.0e-117	65.7
WP_011835384.1\|1517950_1518886_-	ABC transporter permease	NA	NA	NA	NA
WP_011835385.1\|1518878_1519571_-	cell division ATP-binding protein FtsE	G9BWD6	Planktothrix_phage	1.2e-31	34.8

DBSCAN-SWA_10

2018736 : 2110526

111

Lactococcus_phage(74.19%)

head,transposase,tRNA,protease,capsid,portal,terminase,integrase,holin,tail

attL 2063322:2063344|attR 2107500:2107522

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_011835755.1\|2018736_2020614_-\|tRNA	tRNA uridine-5-carboxymethylaminomethyl(34) synthesis enzyme MnmG	NA	NA	NA	NA
WP_011676860.1\|2020998_2021562_-	hypothetical protein	NA	NA	NA	NA
WP_011835756.1\|2021694_2022063_-	DUF1033 family protein	NA	NA	NA	NA
WP_014735129.1\|2022176_2022578_-	Mini-ribonuclease 3	NA	NA	NA	NA
WP_011835758.1\|2022570_2023917_-\|tRNA	cysteine--tRNA ligase	A0A2L2DK39	Acanthamoeba_polyphaga_mimivirus	8.8e-50	30.9
WP_011676864.1\|2023929_2024523_-	DUF1211 domain-containing protein	NA	NA	NA	NA
WP_011835759.1\|2024536_2025136_-	serine O-acetyltransferase	NA	NA	NA	NA
WP_011835760.1\|2025241_2026012_-	hypothetical protein	NA	NA	NA	NA
WP_011835761.1\|2026279_2028580_-	polyribonucleotide nucleotidyltransferase	NA	NA	NA	NA
WP_011835762.1\|2028860_2030006_-	hypothetical protein	NA	NA	NA	NA
WP_011835763.1\|2030370_2031336_+	ribose-phosphate diphosphokinase	A0A2K9L2G2	Tupanvirus	1.8e-36	32.8
WP_011676870.1\|2031440_2031872_-	universal stress protein	NA	NA	NA	NA
WP_041931211.1\|2032171_2033296_+	cysteine desulfurase	H7BUW1	unidentified_phage	3.1e-32	37.1
WP_011835765.1\|2033321_2033666_+	DUF1831 domain-containing protein	NA	NA	NA	NA
WP_003132374.1\|2033754_2034942_-	elongation factor Tu	A0A076FFS6	Aureococcus_anophage	2.0e-34	29.4
WP_011835766.1\|2035185_2035368_+	hypothetical protein	NA	NA	NA	NA
WP_011835767.1\|2035426_2035543_+	DUF4044 domain-containing protein	NA	NA	NA	NA
WP_011835768.1\|2035602_2038401_-\|tRNA	isoleucine--tRNA ligase	A0A1V0SJ93	Klosneuvirus	8.7e-84	26.2
WP_011835770.1\|2038847_2039783_-	DivIVA domain-containing protein	NA	NA	NA	NA
WP_014735130.1\|2039839_2040631_-	RNA-binding protein	NA	NA	NA	NA
WP_011676877.1\|2040627_2040903_-	YggT family protein	NA	NA	NA	NA
WP_011835772.1\|2040902_2041493_-	cell division protein SepF	NA	NA	NA	NA
WP_011835773.1\|2041526_2042204_-	YggS family pyridoxal phosphate-dependent enzyme	NA	NA	NA	NA
WP_011835774.1\|2042200_2043460_-	cell division protein FtsZ	NA	NA	NA	NA
WP_011835775.1\|2043489_2044860_-	cell division protein FtsA	NA	NA	NA	NA
WP_011835776.1\|2045021_2045891_-	DegV family protein	A0A0N9SI50	Staphylococcus_phage	1.7e-14	35.3
WP_011835777.1\|2046007_2046736_-	23S rRNA (guanosine(2251)-2'-O)-methyltransferase RlmB	A0A2D1A6G0	Rhodococcus_phage	6.1e-05	27.7
WP_011835778.1\|2046899_2048000_-	FAD-binding oxidoreductase	NA	NA	NA	NA
WP_011835779.1\|2048137_2048983_-	aldo/keto reductase	A0A1V0SDE7	Indivirus	4.0e-32	33.7
WP_011835780.1\|2048994_2050320_-	MFS transporter	NA	NA	NA	NA
WP_011835781.1\|2050434_2051313_-	LysR family transcriptional regulator	NA	NA	NA	NA
WP_011835782.1\|2051328_2051733_-	MerR family transcriptional regulator	NA	NA	NA	NA
WP_011676889.1\|2051812_2053123_-	aminopeptidase C	R4TV59	Phaeocystis_globosa_virus	1.5e-62	31.7
WP_011835784.1\|2053251_2053926_-	HD domain-containing protein	NA	NA	NA	NA
WP_011835785.1\|2053943_2054447_-	hypothetical protein	NA	NA	NA	NA
WP_011835787.1\|2054583_2055264_-	5'-methylthioadenosine/adenosylhomocysteine nucleosidase	NA	NA	NA	NA
WP_011676893.1\|2055291_2055570_-	hypothetical protein	NA	NA	NA	NA
WP_011835788.1\|2055562_2056147_-	NUDIX hydrolase	NA	NA	NA	NA
WP_011835789.1\|2056247_2057624_-	bifunctional UDP-N-acetylglucosamine diphosphorylase/glucosamine-1-phosphate N-acetyltransferase GlmU	A0A0G2Y8M0	Acanthamoeba_polyphaga_mimivirus	1.2e-30	35.7
WP_011835790.1\|2057844_2058636_+	pyrroline-5-carboxylate reductase	A0A1X9I6T5	Streptococcus_phage	1.1e-31	33.2
WP_010906184.1\|2058719_2058989_-	30S ribosomal protein S15	NA	NA	NA	NA
WP_011835791.1\|2059159_2061037_-	Stk1 family PASTA domain-containing Ser/Thr kinase	A0A1V0SDC3	Indivirus	9.8e-23	32.4
WP_011835792.1\|2061036_2061813_-	Stp1/IreP family PP2C-type Ser/Thr phosphatase	NA	NA	NA	NA
WP_011835793.1\|2061935_2063210_-	16S rRNA (cytosine(967)-C(5))-methyltransferase RsmB	NA	NA	NA	NA
2063322:2063344	attL	NA	NA	NA	NA
WP_011835794.1\|2064417_2065275_-	lysozyme	Q8LTJ6	Lactococcus_phage	2.8e-102	88.6
WP_011835795.1\|2065276_2065738_-\|holin	phage holin	Q8LTJ7	Lactococcus_phage	1.2e-46	89.7
WP_011835796.1\|2065753_2066101_-	hypothetical protein	Q38132	Lactococcus_phage	7.5e-54	99.1
WP_011835797.1\|2066113_2066350_-	hypothetical protein	Q38320	Lactococcus_phage	3.2e-32	93.6
WP_011835798.1\|2066365_2071219_-	serine/threonine protein phosphatase	Q38319	Lactococcus_phage	0.0e+00	50.3
WP_011835799.1\|2071215_2072298_-\|tail	phage tail component	Q38318	Lactococcus_phage	1.9e-151	73.1
WP_011835800.1\|2072221_2072869_-\|tail	phage tail family protein	Q38318	Lactococcus_phage	1.3e-86	75.4
WP_011835801.1\|2072865_2078013_-\|tail	phage tail tape measure protein	Q8LTK2	Lactococcus_phage	0.0e+00	91.5
WP_011835802.1\|2078235_2078652_-	hypothetical protein	Q8LTK3	Lactococcus_phage	3.0e-65	98.6
WP_011835803.1\|2078796_2079390_-\|tail	tail protein	Q94MA4	Lactococcus_phage	8.4e-106	100.0
WP_011835804.1\|2079420_2079816_-	DUF806 family protein	Q9AZS3	Lactococcus_phage	5.7e-66	99.2
WP_011835805.1\|2079812_2080319_-	HK97 gp10 family phage protein	Q8LTK6	Lactococcus_phage	1.3e-86	98.2
WP_011835806.1\|2080320_2080671_-\|head	phage head closure protein	Q8LTK7	Lactococcus_phage	3.4e-54	94.8
WP_011835807.1\|2080645_2080969_-\|head,tail	phage gp6-like head-tail connector protein	Q94MA8	Lactococcus_phage	7.7e-53	98.1
WP_011835808.1\|2081169_2082384_-\|capsid	phage major capsid protein	Q9AZS7	Lactococcus_phage	3.1e-219	99.8
WP_010905934.1\|2082395_2083103_-\|protease	Clp protease ClpP	Q9AZS8	Lactococcus_phage	1.4e-120	100.0
WP_014735131.1\|2083145_2084324_-\|portal	phage portal protein	Q77P35	Lactococcus_phage	2.0e-223	99.2
WP_011835810.1\|2084320_2084530_-	DUF1056 family protein	Q9AZT0	Lactococcus_phage	1.5e-28	98.6
WP_011835811.1\|2084498_2086097_-\|terminase	terminase large subunit	Q8LTL2	Lactococcus_phage	6.9e-304	97.0
WP_011835812.1\|2087719_2088118_-\|terminase	phage terminase small subunit P27 family	Q8LTL3	Lactococcus_phage	4.9e-17	38.8
WP_011835813.1\|2088299_2088818_-	HNH endonuclease	Q94M78	Lactococcus_phage	2.5e-98	97.1
WP_011835814.1\|2088821_2089112_-	hypothetical protein	NA	NA	NA	NA
WP_011835815.1\|2089488_2089890_-	RinA family protein	Q9AZZ1	Lactococcus_phage	1.2e-68	99.2
WP_011835816.1\|2089972_2090158_-	hypothetical protein	Q8LTL6	Lactococcus_phage	1.6e-26	98.3
WP_011835817.1\|2090154_2090463_-	hypothetical protein	NA	NA	NA	NA
WP_014735134.1\|2090464_2090644_-	hypothetical protein	NA	NA	NA	NA
WP_162466997.1\|2090645_2090786_-	hypothetical protein	Q8LTL7	Lactococcus_phage	1.7e-20	97.8
WP_003331414.1\|2090894_2091653_-	ATP-binding protein	A0A059NT77	Lactococcus_phage	5.3e-137	100.0
WP_003331415.1\|2091664_2092888_-\|transposase	IS21-like element IS712 family transposase	A0A059NT83	Lactococcus_phage	4.9e-233	100.0
WP_014735135.1\|2092943_2093087_-	hypothetical protein	Q8LTL7	Lactococcus_phage	6.9e-14	90.0
WP_011835819.1\|2093447_2093657_+	hypothetical protein	NA	NA	NA	NA
WP_014735136.1\|2093705_2093906_-	DUF1660 domain-containing protein	A0A1P8BKA6	Lactococcus_phage	2.5e-30	84.8
WP_011835820.1\|2093902_2094133_-	hypothetical protein	A0A1P8BMS6	Lactococcus_phage	5.7e-10	46.2
WP_011835821.1\|2094151_2094490_-	DUF1140 family protein	A0A1B1IMW5	Lactococcus_phage	3.3e-54	95.5
WP_011835822.1\|2094490_2094910_-	dUTP diphosphatase	Q9MBX9	Lactococcus_phage	1.6e-71	98.6
WP_011835823.1\|2094906_2095464_-	DUF1642 domain-containing protein	Q9AZU5	Lactococcus_phage	4.2e-22	47.3
WP_011835824.1\|2095479_2095716_-	hypothetical protein	A0A023J2W2	Lactococcus_phage	2.8e-12	55.7
WP_014735137.1\|2095696_2095891_-	hypothetical protein	A0A1P8BKQ8	Lactococcus_phage	2.9e-23	91.5
WP_011835825.1\|2095887_2096085_-	DUF1125 domain-containing protein	NA	NA	NA	NA
WP_011835826.1\|2096085_2096352_-	hypothetical protein	NA	NA	NA	NA
WP_011835827.1\|2096332_2096665_-	hypothetical protein	Q9G0E0	Lactococcus_phage	2.8e-10	85.3
WP_011835830.1\|2097311_2097551_-	DUF1031 domain-containing protein	A0A059NT75	Lactococcus_phage	2.3e-38	98.7
WP_011835831.1\|2097547_2097922_-	DUF1064 domain-containing protein	Q9AZV2	Lactococcus_phage	5.2e-61	97.6
WP_011835832.1\|2097918_2098644_-	hypothetical protein	A0A1P8BKN5	Lactococcus_phage	1.4e-131	97.9
WP_011835833.1\|2098643_2099426_-	phage replisome organiser protein	A0A1P8BKN4	Lactococcus_phage	8.2e-125	95.4
WP_011835834.1\|2099554_2099980_-	single-stranded DNA-binding protein	Q9MC32	Lactococcus_phage	8.0e-74	97.9
WP_011835835.1\|2099972_2100107_-	translation initiation factor	Q0ILF6	Lactococcus_phage	2.4e-16	93.2
WP_011835836.1\|2100359_2100731_-	hypothetical protein	Q0ILF6	Lactococcus_phage	3.3e-68	100.0
WP_011835837.1\|2100739_2101135_-	hypothetical protein	A0A1P8BL23	Lactococcus_phage	2.5e-69	99.2
WP_011835838.1\|2101233_2101476_-	hypothetical protein	A0A1B1IMF7	Lactococcus_phage	3.7e-36	97.5
WP_014735139.1\|2101583_2101961_+	DUF2513 domain-containing protein	Q4ZCQ5	Staphylococcus_virus	7.2e-18	36.0
WP_011835840.1\|2101953_2102157_-	hypothetical protein	A0A2H4JBS5	uncultured_Caudovirales_phage	9.8e-06	39.2
WP_011835841.1\|2102252_2102522_-	hypothetical protein	NA	NA	NA	NA
WP_011835842.1\|2102535_2103294_-	phage repressor protein/antirepressor Ant	A0A1B1IMQ3	Lactococcus_phage	4.4e-91	72.2
WP_011835843.1\|2103306_2103555_-	helix-turn-helix transcriptional regulator	J7KK54	Streptococcus_phage	2.2e-07	51.7
WP_011835844.1\|2103659_2103896_+	hypothetical protein	NA	NA	NA	NA
WP_011835845.1\|2103867_2104089_-	hypothetical protein	NA	NA	NA	NA
WP_014735140.1\|2104463_2104661_-	hypothetical protein	NA	NA	NA	NA
WP_011835847.1\|2104944_2105442_+	helix-turn-helix domain-containing protein	J7KJ52	Streptococcus_phage	1.7e-22	50.4
WP_011835848.1\|2105447_2105882_+	zinc peptidase	NA	NA	NA	NA
WP_011835849.1\|2105895_2106231_+	hypothetical protein	NA	NA	NA	NA
WP_014735141.1\|2106298_2107480_+\|integrase	site-specific integrase	Q9AZK8	Lactococcus_phage	2.0e-90	47.5
WP_011676957.1\|2107774_2108281_-	Asp23/Gls24 family envelope stress response protein	NA	NA	NA	NA
2107500:2107522	attR	NA	NA	NA	NA
WP_011676958.1\|2108290_2108479_-	DUF2273 domain-containing protein	NA	NA	NA	NA
WP_011676959.1\|2108489_2109050_-	alkaline shock response membrane anchor protein AmaP	NA	NA	NA	NA
WP_011676960.1\|2109077_2109320_-	GlsB/YeaQ/YmgE family stress response membrane protein	NA	NA	NA	NA
WP_011835851.1\|2109554_2110526_-\|tRNA	methionyl-tRNA formyltransferase	NA	NA	NA	NA

DBSCAN-SWA_11

2212624 : 2227565

Lactococcus_phage(87.5%)

integrase,terminase

attL 2209415:2209430|attR 2227651:2227666

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
2209415:2209430	attL	NA	NA	NA	NA
WP_011835936.1\|2212624_2212957_-	hypothetical protein	Q9AZE0	Lactococcus_phage	4.8e-50	90.7
WP_011835937.1\|2212956_2213397_-\|terminase	terminase small subunit	Q9AZI3	Lactococcus_phage	8.3e-58	89.0
WP_011677047.1\|2213529_2214072_-	hypothetical protein	Q9AZI4	Lactococcus_phage	9.3e-51	82.2
WP_011835938.1\|2214288_2215917_-	DNA primase	Q9AZI5	Lactococcus_phage	1.4e-296	91.9
WP_011835939.1\|2215927_2216722_-	bifunctional DNA primase/polymerase	Q9AZI6	Lactococcus_phage	1.8e-151	95.8
WP_011835940.1\|2216718_2217054_-	hypothetical protein	Q9AZI7	Lactococcus_phage	4.2e-54	95.4
WP_011835941.1\|2217123_2217363_-	hypothetical protein	Q9AZJ0	Lactococcus_phage	5.3e-35	87.3
WP_011835942.1\|2217400_2217682_-	hypothetical protein	Q9AZJ1	Lactococcus_phage	2.5e-44	93.5
WP_011835945.1\|2217903_2218107_-	hypothetical protein	NA	NA	NA	NA
WP_011835946.1\|2218103_2218625_-	hypothetical protein	Q9AZJ3	Lactococcus_phage	7.0e-72	78.9
WP_011835947.1\|2218883_2219549_-	Rha family transcriptional regulator	R9QNB1	Lactococcus_phage	1.2e-47	48.7
WP_014735153.1\|2219711_2219933_-	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_011835948.1\|2220103_2220646_+	helix-turn-helix transcriptional regulator	A0A0P0IV68	Lactobacillus_phage	3.3e-08	50.8
WP_014735154.1\|2220867_2221098_+	hypothetical protein	Q9AZK0	Lactococcus_phage	3.5e-15	84.2
WP_014735155.1\|2221170_2221365_+	hypothetical protein	Q9AZK1	Lactococcus_phage	2.5e-27	93.8
WP_011835949.1\|2221546_2222281_+	hypothetical protein	NA	NA	NA	NA
WP_011835950.1\|2222486_2222672_+	hypothetical protein	NA	NA	NA	NA
WP_011835951.1\|2222858_2223923_+	hypothetical protein	A0A141E0C6	Streptococcus_phage	1.6e-102	54.6
WP_011835952.1\|2224574_2224889_+	hypothetical protein	NA	NA	NA	NA
WP_011835953.1\|2225692_2225887_+	hypothetical protein	Q9AZK6	Lactococcus_phage	3.7e-10	62.3
WP_011835954.1\|2226383_2227565_+\|integrase	site-specific integrase	Q9AZK8	Lactococcus_phage	3.1e-91	46.2
2227651:2227666	attR	NA	NA	NA	NA

DBSCAN-SWA_12

2479372 : 2491949

Lactococcus_phage(92.31%)

integrase

attL 2480030:2480045|attR 2489020:2489035

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_011836143.1\|2479372_2481373_-	ATP-dependent DNA helicase RecG	B2CRJ8	Acidianus_filamentous_virus	2.1e-07	24.0
2480030:2480045	attL	NA	NA	NA	NA
WP_041931367.1\|2481511_2481838_-	alkylphosphonate utilization protein	NA	NA	NA	NA
WP_011836145.1\|2481926_2483105_-\|integrase	site-specific integrase	Q9AZK8	Lactococcus_phage	3.6e-92	46.8
WP_011836146.1\|2483632_2484235_-	helix-turn-helix transcriptional regulator	A0A1P8BMN9	Lactococcus_phage	1.5e-12	59.1
WP_014735188.1\|2484396_2484600_+	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_011836147.1\|2484618_2485311_+	Bro-N domain-containing protein	Q9AZJ5	Lactococcus_phage	1.1e-19	47.8
WP_011836148.1\|2485564_2486098_+	hypothetical protein	Q9AZJ3	Lactococcus_phage	2.0e-50	62.1
WP_011836149.1\|2486090_2486372_+	hypothetical protein	Q9AZJ1	Lactococcus_phage	6.1e-46	94.6
WP_011836150.1\|2486414_2486654_+	hypothetical protein	Q9AZJ0	Lactococcus_phage	6.3e-36	91.1
WP_011836152.1\|2486901_2487231_+	hypothetical protein	Q9AZI7	Lactococcus_phage	2.9e-55	95.4
WP_011836153.1\|2487339_2488134_+	bifunctional DNA primase/polymerase	Q9AZI6	Lactococcus_phage	1.5e-150	94.7
WP_011836154.1\|2488144_2489773_+	DNA primase	Q9AZI5	Lactococcus_phage	3.4e-298	92.3
2489020:2489035	attR	NA	NA	NA	NA
WP_011836155.1\|2490000_2490543_+	hypothetical protein	Q9AZI4	Lactococcus_phage	4.2e-59	71.4
WP_011836156.1\|2490815_2491118_+	hypothetical protein	NA	NA	NA	NA
WP_011836157.1\|2491191_2491602_+	DUF722 domain-containing protein	Q9AZI2	Lactococcus_phage	8.2e-68	94.9
WP_011836158.1\|2491625_2491949_+	sigma-70 family RNA polymerase sigma factor	Q9AZI1	Lactococcus_phage	7.4e-48	89.7

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. NC_009004

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Click the colored protein region to show detailed information

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection