CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Target MGE spacer number	Prophage number
NC_011001	Burkholderia cenocepacia J2315 chromosome 2, complete sequence	1 crisprs	cas3,csa3,PD-DExK,RT,DinG	0	2
NC_011002	Burkholderia cenocepacia J2315 chromosome 3, complete sequence	0 crisprs	RT,PD-DExK	0	1
NC_011000	Burkholderia cenocepacia J2315 chromosome 1, complete sequence	0 crisprs	DEDDh,DinG,csa3,cas3,WYL	0	9
NC_011003	Burkholderia cenocepacia J2315 plasmid pBCJ2315, complete sequence	1 crisprs	RT	2	0

Results visualization

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CRISPR-Cas detection and classification

Crispr_ID: NC_011003_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_011003_1

1785-1971

Orphan

Consensus_repeat	Method
TGTAGTGTCGTTCTTCCAGCGATGCT	PILER-CR

2 spacers

The CRISPR arrays of NC_011003_1

>merge|NC_011003|1|1785-1971|PILER-CR
GTGACGTTCTTCCAGCGATGCTCTATATGGGACGGGCATGAGCGTGAGAGTGTGTACTCACCTTGCTCGGGGGGCAGCTTGACGGTGTCGTGTCGTTCTTCCAGCGATGCTGATAGGGCGCGGTCGTTCCTCCAGCGATGGTCGAGATGCCCTCTCTGTCCTGTACTGTCGTTCTTCCAGCGATGAT

>NC_011003|1|1|1785-1971|PILER-CR
GTGACGTTCTTCCAGCGATGCTCTAT	ATGGGACGGGCATGAGCGTGAGAGTGTGTACTCACCTTGCTCGGGGGGCAGCTTGACGGTGTC
GTGTCGTTCTTCCAGCGATGCTGATA	GGGCGCGGTCGTTCCTCCAGCGATGGTCGAGATGCCCTCTCTGTCCTGTA
CTGTCGTTCTTCCAGCGATGAT

Protein	Signature genes	Signature genes Name	Protein_function
NC_011003.1\|WP_006482121.1\|4208_7358_-\|error-prone-DNA-polymerase	unknown	unknown	gnl\|CDD\|235553
NC_011003.1\|WP_006482119.1\|0_672_+\|AAA-family-ATPase	unknown	unknown	gnl\|CDD\|349760
NC_011003.1\|WP_012492258.1\|9880_11413_+\|group-II-intron-reverse-transcriptase/maturase	RT	pfam00078_RT_CAS-I:CAS-III	gnl\|CDD\|275209
NC_011003.1\|WP_006482109.1\|2362_3220_+\|replication-initiator-protein-A	unknown	unknown	gnl\|CDD\|115680
NC_011003.1\|WP_006487437.1\|13075_14062_-\|hypothetical-protein	unknown	unknown	unknown
NC_011003.1\|WP_006487390.1\|15125_19508_-\|hemagglutinin	unknown	unknown	gnl\|CDD\|380308
NC_011003.1\|WP_006493623.1\|8763_9480_-\|translesion-DNA-synthesis-associated-protein-ImuA	unknown	unknown	gnl\|CDD\|380271
NC_011003.1\|WP_012493831.1\|7364_8843_-\|DNA-polymerase-Y-family-protein	unknown	unknown	gnl\|CDD\|176458
NC_011003.1\|WP_006482114.1\|671_1637_+\|ParB/RepB/Spo0J-family-partition-protein	unknown	unknown	gnl\|CDD\|272946
NC_011003.1\|WP_006487427.1\|14315_15089_-\|hypothetical-protein	unknown	unknown	unknown
NC_011003.1\|WP_006487412.1\|20223_21036_-\|hypothetical-protein	unknown	unknown	unknown
NC_011003.1\|WP_006493938.1\|11468_12380_-\|SOS-response-associated-peptidase-family-protein	unknown	unknown	gnl\|CDD\|376837

Protein	Function_ID	Function_description	E-value
NC_011003.1\|WP_006482114.1\|671_1637_+\|ParB/RepB/Spo0J-family-partition-protein	gnl\|CDD\|272946	TIGR00180, Probable_chromosome-partitioning_protein_ParB, ParB/RepB/Spo0J family partition protein. This model represents the most well-conserved core of a set of chromosomal and plasmid partition proteins related to ParB, including Spo0J, RepB, and SopB. Spo0J has been shown to bind a specific DNA sequence that, when introduced into a plasmid, can serve as partition site. Study of RepB, which has nicking-closing activity, suggests that it forms a transient protein-DNA covalent intermediate during the strand transfer reaction.	2.37522e-18
NC_011003.1\|WP_006482119.1\|0_672_+\|AAA-family-ATPase	gnl\|CDD\|349760	cd02042, ParAB_family, partition proteins ParAB family. ParA and ParB of Caulobacter crescentus belong to a conserved family of bacterial proteins implicated in chromosome segregation. ParB binds to DNA sequences adjacent to the origin of replication and localizes to opposite cell poles shortly following the initiation of DNA replication. ParB regulates the ParA ATPase activity by promoting nucleotide exchange in a fashion reminiscent of the exchange factors of eukaryotic G proteins. ADP-bound ParA binds single-stranded DNA, whereas the ATP-bound form dissociates ParB from its DNA binding sites. Increasing the fraction of ParA-ADP in the cell inhibits cell division, suggesting that this simple nucleotide switch may regulate cytokinesis. ParA shares sequence similarity to a conserved and widespread family of ATPases which includes the repA protein of the repABC operon in Rhizobium etli symbiotic plasmid. This operon is involved in the plasmid replication and partition.	2.21888e-25
NC_011003.1\|WP_012492258.1\|9880_11413_+\|group-II-intron-reverse-transcriptase/maturase	gnl\|CDD\|275209	TIGR04416, hypothetical_protein, group II intron reverse transcriptase/maturase. Members of this protein family are multifunctional proteins encoded in most examples of bacterial group II introns. These group II introns are mobile selfish genetic elements, often with multiple highly identical copies per genome. Member proteins have an N-terminal reverse transcriptase (RNA-directed DNA polymerase) domain (pfam00078) followed by an RNA-binding maturase domain (pfam08388). Some members of this family may have an additional C-terminal DNA endonuclease domain that this model does not cover. A region of the group II intron ribozyme structure should be detectable nearby on the genome by Rfam model RF00029. [Mobile and extrachromosomal element functions, Other].	1.72726e-142
NC_011003.1\|WP_006482109.1\|2362_3220_+\|replication-initiator-protein-A	gnl\|CDD\|115680	pfam07042, TrfA, TrfA protein. This family consists of several bacterial TrfA proteins. The trfA operon of broad-host-range IncP plasmids is essential to activate the origin of vegetative replication in diverse species. The trfA operon encodes two ORFs. The first ORF is highly conserved and encodes a putative single-stranded DNA binding protein (Ssb). The second, trfA, contains two translational starts as in the IncP alpha plasmids, generating related polypeptides of 406 (TrfA1) and 282 (TrfA2) amino acids. TrfA2 is very similar to the IncP alpha product, whereas the N-terminal region of TrfA1 shows very little similarity to the equivalent region of IncP alpha TrfA1. This region has been implicated in the ability of IncP alpha plasmids to replicate efficiently in Pseudomonas aeruginosa.	6.5383e-33
NC_011003.1\|WP_006493623.1\|8763_9480_-\|translesion-DNA-synthesis-associated-protein-ImuA	gnl\|CDD\|380271	NF033429, ImuA_translesion, translesion DNA synthesis-associated protein ImuA. A three-gene cassette encoding ImuA, ImuB, and ImuC (""inducible mutagenesis"") is induced by DNA damage, is capable of DNA synthesis across DNA damage lesions, and consequently is associated with mutagenesis. This family, ImuA (previously misnamed SulA in Pseudomonas putida) shows some homology to SulA itself and to RecA. ImuB resembles Y-family polymerases but may be catalytically inactive. ImuC is a C-family polymerase, and catalytically active.	1.23243e-77
NC_011003.1\|WP_006487390.1\|15125_19508_-\|hemagglutinin	gnl\|CDD\|380308	NF033477, EmaA_autotrans, collagen-binding adhesin autotransporter EmaA. EmaA (extracellular matrix protein adhesin ) is an outer membrane protein first described in Aggregatibacter (Actinobacillus) actinomycetemcomitans, a member of the Gammaproteobacteria. It is a glycoprotein, and has a C-terminal beta-barrel domain that marks it as an autotransporter. It serves as an adhesin that binds collagen, the most abundant material in the host extracellular matrix. It shares homology with the collagen-binding protein YadA of Yersinia enterocolitica.	1.42424e-08
NC_011003.1\|WP_006482121.1\|4208_7358_-\|error-prone-DNA-polymerase	gnl\|CDD\|235553	PRK05672, dnaE2, error-prone DNA polymerase; Validated.	0
NC_011003.1\|WP_012493831.1\|7364_8843_-\|DNA-polymerase-Y-family-protein	gnl\|CDD\|176458	cd03468, PolY_like, DNA Polymerase Y-family. Y-family DNA polymerases are a specialized subset of polymerases that facilitate translesion synthesis (TLS), a process that allows the bypass of a variety of DNA lesions. Unlike replicative polymerases, TLS polymerases lack proofreading activity and have low fidelity and low processivity. They use damaged DNA as templates and insert nucleotides opposite the lesions. The active sites of TLS polymerases are large and flexible to allow the accomodation of distorted bases. Expression of Y-family polymerases is often induced by DNA damage and is believed to be highly regulated. TLS is likely induced by the monoubiquitination of the replication clamp PCNA, which provides a scaffold for TLS polymerases to bind in order to access the lesion. Because of their high error rates, TLS polymerases are potential targets for cancer treatment and prevention.	5.83065e-59
NC_011003.1\|WP_006493938.1\|11468_12380_-\|SOS-response-associated-peptidase-family-protein	gnl\|CDD\|376837	pfam02586, SRAP, SOS response associated peptidase (SRAP). The SRAP family functions as a DNA-associated autoproteolytic switch that recruits diverse repair enzymes onto DNA damage. We propose that the human protein Q96FZ2:UniProtKB, the eukaryotic member of the SRAP family, which has been recently shown to bind specifically to DNA with 5-hydroxymethylcytosine, 5-formylcytosine and 5-carboxycytosine, is a sensor for these oxidized bases generated by the TET (tetrahedral aminopeptidase of the M42 family) enzymes from methylcytosine. Hence, its autoproteolytic activity might help it act as a switch that recruits DNA repair enzymes to remove these oxidized methylcytosine species as part of the DNA demethylation pathway downstream of the TET enzymes.	5.24258e-13

>NC_011003.1|WP_006482114.1|671_1637_+|ParB/RepB/Spo0J-family-partition-protein
MATFRKKAVAVERVAAVEEAASSAPIVGDPRMAPSLATISQLRGGEVGSSQGATKYEIGQTYEVPIGKIKSNSVNPRAIYTASAVSEMAESLTARGQGQSASAYVDEAGDIVLIDGERRLRGARAAGLPTLRVEIRPKPASERELYEEARAANVERKDQSPLDDALKWKELLSRKIYPTQVALAKALNLGEDHVSRTLSLAQLPSRIVQAAAEYPELLSLKMLNAIREFWEVKGEEETLELVLDAAKTGIGYRDVAARRKAAAKGTVKRPRSTREQLSFRGAKGEFKSFEEDGRIELKLKGLAPDVAAEISEKILALFPKE
>NC_011003.1|WP_006482119.1|0_672_+|AAA-family-ATPase
MVITIGAEKGGVAKTRLATHIAALAAAEDVDVVLLDTDKQGSAMSWSRIRNEEGVTPAIPVLALPANPARELANLANKYTLVVVDIGAQNYRTMLECALLSDLVLVPCGPDQQEVESTLNVFATLKDMGPRHESGEIPAYVVLTRVSPVEGSKATAELRAYLKSEDIRVFDSQIPQREAWRATGKTGRAVHELKGRDRSKKAIDEMEAVYREIIERINGAEVE
>NC_011003.1|WP_006482109.1|2362_3220_+|replication-initiator-protein-A
MANSIVDQVKAIAARASSAGVETQSHPTQIPLWPANVRGMPNALARSALFNVNKSNAPRSRMEKALIASVDGVEISFSGEELRQDDADVFLEVLHLARDTQLNEKVEFTGYSVLKSLGWGTSVKCYDRLVTTLERLQAGQVKVRFTGNKKGFVGSLIRKFLWKEGTETGTDGKTRWVAYVEPEIVALFSDDDYTRLAREQRQRLRYELSKWLHTYYHTHAVPFAHSVRFLHRQCGSQTKELFHFRANLKKALDELVKEGFLVSWTIDKSDLVHVVRASSRGAIAA
>NC_011003.1|WP_006482121.1|4208_7358_-|error-prone-DNA-polymerase
MDAGSFGALPAYAELQVASDFSFLHGASRAEEYVARAAQLGYSAIAITDECSLAGVVRAHVEAKSANMPLIIGSHFQLTAADGSSALAFTALAMNRDGYGNLCEFISLGRMRGKKGSYRLAPLDVDHPEAPYAHLRGLPDCLAILSPDFPANEQRLDAQVEWFARVFGDRAWIALTLHARAMDDIHRGVLERVAARHGVPVVATSWPLMHVRSRKPLQDVLTGIRVGRPVTECGYELAPNAERHLRSRLRLANLYPAGALEETVRVARRCTFSLDDLKYEYPDELVPAGTDPATYLREQTYIGARRRFPAGIPVDVQAQIEHELQLIADMHYEAYFLTVYDIVQFAREQGILCQGRGSAANSAVCYCLGVTEVDPSRQSMLFERFISKERNSPPDIDVDFEHQKREIVMQYIYRKYGRDRAALTAAVTTYRPRSALREAGKALGVDTAIVERVAKQHHWFDSRADLLQRFAEAGLDPEAPLNQQWAAFAAQLLGYPRHLSQHSGGFVISRGKLTRLVPVENAAMEDRSIIQWDKDDIEALGILKIDVLALGMLSMVRRALDMISEKRGETFELQDIPAQDKATYDMLCEGDSMGVFQVESRAQMSMLPRLRPQCFYDLVIEVAIVRPGPVQGGMVHPFLRRRQGLEPVTFPSEGMEKALARTLGVPIFQEQVMQVAMLAAGFSAGEADQLRRAMAAWKRKGGLEPYHERLVSGMLERGYDREFAESIFAQIKGFGEYGFPESHAASFALLVYSSAWLRRHEPAVFLAALLNSQPMGFYTPSQLLQDARRRGVEVLPVDVNVSTWDSAIEGSTTSAPVRLGFSLLRGMREDVAGRIELARAARPFVDVADLARRAQLDRHDLQVLARANALRSLAGGNRRAALWLAAAAVPDRDLLRGTERDDAVPALPQASEGHEIVTDYRAMGFTLGRHPLALLRDRLALDRLQSAEQLATLRSGQLARACGLVTVRQRPGTANGVLFMTLEDETGQVNVILWPGLLEKFRKDALGASLLAVYGVWQAEGKVRHLIASKLVDRTELLGALPTTAREFC
>NC_011003.1|WP_012493831.1|7364_8843_-|DNA-polymerase-Y-family-protein
MQVWIGVHLPHLNLEVFRPRSPAPSPDDARGLVVLEGGRVVALDRAARKLGVVAGMRRGGVLSLAPDAQIRERDAARERELVLGVAYALLQFTPSVVDADEDVVVLDVTASLRLFHGLRALRQRVRDVVASFGVTSAISVASSGPAAWMVARGLRGGLALSARSLRRALARVPLVVAPDARRYANWFEDLGCETLADLQRLPRAGLKKRCGTQLLDWLDQVAGTAPAAYDWLEMPPSFDTRVELMDRVEHAEALLFVARRLILQLTGWLTAKQLDVAAFALLLEHERGREAIAPTEIEIALGAPTRFEEHLTRLVKERLGHVELAGPVIAVRLVARSVQEAAAPSDSLFPEPGGTPQDHARLLELLTARLGAENVLVPAPMADYRPEPAARWVPMRDAPKPAPLPADLPRPAWLLAKPVPLLTRQHRPFYGTPLRMVSPGERIEGGWQDGQTVTRDYFVAEDDHGVCYWIYKERPTASDESEARFFLHGLFG
>NC_011003.1|WP_006493623.1|8763_9480_-|translesion-DNA-synthesis-associated-protein-ImuA
MHPALAHPEAIHPALWRASQLARPSVRGVDTGHLELTAELPGGGWPAGALIELLAPQPGIGELRLLAPVLARTAGKPVMLIQPPHALQPLALAYWGIDPSGFVTLPAPRTADALWAAEQALRAGTCAAVLLWQSHVRADALRRLNLAAQSGQALFYLFRPVAAARDASPAPLRLALAPKRDGIDVTFLKRRGPARDTPLFVPLSPSPILLNRHASLDRRASAAPQPRSVPATIAGAVA
>NC_011003.1|WP_012492258.1|9880_11413_+|group-II-intron-reverse-transcriptase/maturase
MTNGWEKSDSPIVAKKLANKPGQPDAESVERRGGAKGNTEWSRTRRTQSRISVSQRLDRVRQAARQRKKEKFTALYHLIDLDLLATAFFWLKRKAAAGVDGVTWHDYEQDLDRNLEDLHGRLRRQAYRALPSRRRYIPKADGKQRPLGIAALEDKIVQRALVAVLNAVYEMDFLGFSYGFRPQRSQHDALDALATGIARTSVSWILDADISRFFDTVDHDWLIRFVEHRIGDQRVIRLIRKWLKAGAMEDGVIEPTDEGTPQGSVISPLLANIYLHYVFDLWANQWRKRHAEGNVVIVRYADDVVVGFDKPHDAKRFRRAMQQRLEQFGLSVHPEKTRLIEFGRFAARNRASRGLGKPETFNFLGFTHISGRAKDGRFMLMRKTRSDRLRTALKGIKDELRHRWHQSIPEQGDWLRRVVQGYFNYHAVPTNFAALRAFRARVIDLWRLALRRRSQKDDTTWAKMHRLAKQWIPKARILHPWPVVRFDANHPRQEPGARIAHAGICAGGAQ
>NC_011003.1|WP_006493938.1|11468_12380_-|SOS-response-associated-peptidase-family-protein
MCYSAKIQANYREYVRRYGADMDIETFRRIFFARASGADIKIPKAVDAAFAGVDDEISAAIAAYRSQRTRKLETELFEQRARLAAAEKKLAVKITKKASEDVRIATDKIDAATRGLNDLRRQDLQERDSRIFPGWYAPVLIEVDGKRMVVPMRYRCRIPGWTEADEKQKNGSYNARADSLSTAWRKVFGFTHGLLLVDAFFENVKRDGQNVVLRFDPTPPQHMQVACLWTRTEIPGGDDLWSFAAITDDPPPEVAAAGHDRCIVPIKSSNVDAWLAPDPSRRAQLREILADRERPYYEHQLAA
>NC_011003.1|WP_006487437.1|13075_14062_-|hypothetical-protein
MPTPDNTFTNIRSIDVDRQGARLPIGSRVNFPFLDPLLPDQSNPVGVGAPDQLTAAAAPIGAHRMRVAKTVLPERVWPDDIPSPAPANAPRILRELKTRLSRYLDKPAQWLAQLNAANGSRRQQRSERRLACVQLARAMIKYCDLRTMRIGVPGAAGWIDFTLPYLAAQAGLSERRAERALRDLQKARLVKVRRQCELEETEQGVRYKGVASIKYLTSTLFESFGLGKWLRHERTRAHLRAQRRANQQRKRTQQGSALGAQLVEQLAGIEARARRQAAAAGAAQREAVDLDRAIKLRVGELLHAHPDWDRDTLYAAARRQLAPPGDSV
>NC_011003.1|WP_006487427.1|14315_15089_-|hypothetical-protein
MKRPNYRSALLAACVAVAAFLVTACFGHRAWPIVAATLLAIPLASLFVKATNRWRRQQAVDRPSVTITEATVWELRLNDVPAAEVPEHVVRRIEHELAQERQWDLRVASILSYAGAVLCQLAYTALCIPLAIFAFAGLSWATNPAGFAHLARQILNASETELRAVVDGLAWTAIGFSGMVLVMWHAFGGRTRIPDHYDEAWHEEIRLAARIAPRGEFTLHLSGQVVPAGFRVTRGPRLTVHYWPNSRRSSPNRHDVA
>NC_011003.1|WP_006487390.1|15125_19508_-|hemagglutinin
MGVDAHASGNSVAAGANSYAGWRDTAVGVQATATGDTSVAIGYQSNDAGRDRVVSVGASGLTRAVTNVTAGTTTTDAANVGQLPGTINGNVVTMGNMLTPGASVGPATVTNVAPGTLTGGSTDAVNGSQLFTTNLAVTTHKQMLDNLSGRVVNGTIGLVQQQAGAPGSGTITVGAQTGGTSVDLTGTDGARTISGVAAGTATTDAVNVGQLNTVASVASNSVQYDTTGHTSVTLGGAAAAAPVALTNVAAGTLSATSVDAVNGAQLFAANQAVANTSTSVTNLTNGINAGTVGLVQQTGGAPGSGPIAVGAQTGGMSVDFTGTNGARTLSGVAAGTATTDAVNVGQLSAVAGATANAVQYDSTGHTSVTLGGTTAASPVALTNVAAGTLSASSTDAVNGSQLNTTNQAVANTSTSVTNLMSGINAGTVGLVQQAGGAPGTGTITVGAQTSGTAVDFAGTNGARTLSGVAGGTATTDAVNVGQLNVVASTASNSVQYDNAGHTSVTLGGTAAAAPVALTNVAAGTLSASSTDAVNGAQLNTTNQAVANTSTSVTNLSASINAGTVGLVQQAGGAPGRGTITVGVQTGGTTVDFAGTNGARTLSGVAAGIAATDVVNVGQLDAVAGTASNSVQYDNADHTVVTLGGTAAGAPVALRNVAAGTLSAASADAVNGAQLFATNQAVASTSTSVTNLSASIDAGTVGLVRQAGGAPGSGPITVGAQTGGLSVDFAGTTGPRTLAGVAAGTAATDAVNVGQLSTVAGTASNSVQYDNAGHTSVTLGGTAAAAPVALTNVAAGTLSAASTDAVNGAQLNTTNQAVASTSRSLMNLSASIDAGTVGVVQQVGGAPGRGAITVGAQTGGTSVDFAGTSGARTLSGVAAGTAATDAVNVGQLGAVAGVAANAVQYDNAGHTSVTLGGASAAASVALTNVAAGTLSASSVDAVNGGQLFATNQAVANTSTVVTNLSNGIAAGTVGLVQQAGGAPGTGQITVGGQTGGTSVDFSGTDGTRKLSGVAAGTAATDAVNVSQLNAVAGVATNAVQYDNAGRTSVTLGGAGAAAPVALTNVAAGALSASSTDAVNGAQLYATNQALSGTTSTVNALSTGIAAGTIGLVQQAGGAPGTGMITIGAKTGGTAIDVSGTSGARQLKGVAAGTDATDAVNVSQLNATISSATANAVVYDSAARSIVTLGGLGASVPVTLRNVAAGVLSGNSTDAVNGSQLYMTNQAVAANTGAIDALTNSLTDVQRSMARNAAQLQPIVSADALKYFAASSTGAPASASGTETVAAGGNALAAGAHSVAIGTGAQAIGSGALALGANTSAKGSNSIALGQGSDASADNTVSIGNSATGLTRTLTNVSAGGAPTDAVNVRQLSDAVGGLRSQIEHDRADANGGSASAVAIASLPQAPAPGHSVVSIGGGTYAGQSAVAVGMSTYAGRWILKASGSTNTRGTVAAGAGAAYVW
>NC_011003.1|WP_006487412.1|20223_21036_-|hypothetical-protein
MSQHVKDYLTPDEAMQMLHAQLSHGADLYRFLLTRRVMHLTGGVVQHGPLAGFNIGRHATWREEDNASKVLGFYEQEVCALLDRLSGRCDVLVDLGGADGFYAVGMVERGHFRESHCFEIEDQSRANIAAIAADNGVAGRVHLYGAATSTFARDLTAAGVDFRRAAVLVDIESNEFEVLNTQCLHDLRHSHVIVEIHDFMRPHDGAQRYAELRERAQVDFHVHSFTTGARDPSSIPFLRNGWTDTDRWLLCSESRATLMTWLYLEPKETC

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NC_011003_1	1.2\|1900\|50\|NC_011003\|PILER-CR	1900-1949	50	NC_011003	Burkholderia cenocepacia J2315 plasmid pBCJ2315, complete sequence	1896-1945	0	1.0
NC_011003_1	1.2\|1900\|50\|NC_011003\|PILER-CR	1900-1949	50	NC_008545	Burkholderia cenocepacia HI2424 plasmid unnamed1, complete sequence	92027-92076	0	1.0
NC_011003_1	1.1\|1811\|63\|NC_011003\|PILER-CR	1811-1873	63	NC_011003	Burkholderia cenocepacia J2315 plasmid pBCJ2315, complete sequence	1807-1869	3	0.952
NC_011003_1	1.1\|1811\|63\|NC_011003\|PILER-CR	1811-1873	63	NC_008545	Burkholderia cenocepacia HI2424 plasmid unnamed1, complete sequence	92103-92165	3	0.952

1. spacer 1.2|1900|50|NC_011003|PILER-CR matches to NC_011003 (Burkholderia cenocepacia J2315 plasmid pBCJ2315, complete sequence) position: , mismatch: 0, identity: 1.0

gatagggcgcggtcgttcctccagcgatggtcgagatgccctctctgtcc	CRISPR spacer
gatagggcgcggtcgttcctccagcgatggtcgagatgccctctctgtcc	Protospacer
**************************************************

2. spacer 1.2|1900|50|NC_011003|PILER-CR matches to NC_008545 (Burkholderia cenocepacia HI2424 plasmid unnamed1, complete sequence) position: , mismatch: 0, identity: 1.0

gatagggcgcggtcgttcctccagcgatggtcgagatgccctctctgtcc	CRISPR spacer
gatagggcgcggtcgttcctccagcgatggtcgagatgccctctctgtcc	Protospacer
**************************************************

3. spacer 1.1|1811|63|NC_011003|PILER-CR matches to NC_011003 (Burkholderia cenocepacia J2315 plasmid pBCJ2315, complete sequence) position: , mismatch: 3, identity: 0.952

ctatatgggacgggcatgagcgtgagagtgtgtactcaccttgctcggggggcagcttga	CRISPR spacer
ctatatgggacgggcatgagcgtgagagtgtgtactcaccttgctcggggggcagcttga	Protospacer
************************************************************

4. spacer 1.1|1811|63|NC_011003|PILER-CR matches to NC_008545 (Burkholderia cenocepacia HI2424 plasmid unnamed1, complete sequence) position: , mismatch: 3, identity: 0.952

ctatatgggacgggcatgagcgtgagagtgtgtactcaccttgctcggggggcagcttga	CRISPR spacer
ctatatgggacgggcatgagcgtgagagtgtgtactcaccttgctcggggggcagcttga	Protospacer
************************************************************

Prophage detection

Region	Region Position	Protein_number	Hit_taxonomy	Key_proteins	Att_site	Prophage annotation

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

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CRISPR-Cas detection and classification

Crispr_ID: NC_011001_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_011001_1

1395471-1395579

Orphan

Consensus_repeat	Method
CCTTGCGGCGGCCCGGCGGAGGCTGA	CRISPRCasFinder

1 spacers

csa3

The CRISPR arrays of NC_011001_1

>merge|NC_011001|1|1395471-1395579|CRISPRCasFinder
CCTTGCGGCGGCCCGGCGGAGGCTGAGATGAAACGACCCCCACGCTCACTTTGTTCGCTGCCCCCCGCGGGGGCGGTCAGCCTCCTTGGGGCGGCCCGGCGGAGGCTGA

>NC_011001|1|1|1395471-1395579|CRISPRCasFinder
CCTTGCGGCGGCCCGGCGGAGGCTGA	GATGAAACGACCCCCACGCTCACTTTGTTCGCTGCCCCCCGCGGGGGCGGTCAGCCT
CCTTGGGGCGGCCCGGCGGAGGCTGA

Protein	Signature genes	Signature genes Name	Protein_function
NC_011001.1\|WP_006484863.1\|1392069_1392990_-\|dihydrodipicolinate-synthase-family-protein	unknown	unknown	gnl\|CDD\|188630
NC_011001.1\|WP_006491047.1\|1387540_1388563_-\|Ldh-family-oxidoreductase	unknown	unknown	gnl\|CDD\|224966
NC_011001.1\|WP_006488719.1\|1398237_1399281_+\|gentisate-1,2-dioxygenase	unknown	unknown	gnl\|CDD\|131325
NC_011001.1\|WP_006488722.1\|1399368_1400067_+\|fumarylacetoacetate-hydrolase-family-protein	unknown	unknown	gnl\|CDD\|223257
NC_011001.1\|WP_006488711.1\|1400101_1400743_+\|maleylacetoacetate-isomerase	unknown	unknown	gnl\|CDD\|273527
NC_011001.1\|WP_006488726.1\|1403865_1404300_+\|YeeE/YedE-family-protein	unknown	unknown	gnl\|CDD\|225264
NC_011001.1\|WP_006484864.1\|1393241_1394174_+\|4-hydroxyproline-epimerase	unknown	unknown	gnl\|CDD\|172473
NC_011001.1\|WP_006484690.1\|1383908_1384361_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|237864
NC_011001.1\|WP_006491351.1\|1395580_1395814_+\|(2Fe-2S)-binding-protein	unknown	unknown	gnl\|CDD\|379229
NC_011001.1\|WP_012493270.1\|1384394_1385258_+\|peptide-binding-protein	unknown	unknown	gnl\|CDD\|227324
NC_011001.1\|WP_006491048.1\|1388555_1390148_-\|aldehyde-dehydrogenase-(NADP(+))	unknown	unknown	gnl\|CDD\|143447
NC_011001.1\|WP_006495056.1\|1394170_1395298_+\|FAD-binding-oxidoreductase	unknown	unknown	gnl\|CDD\|223737
NC_011001.1\|WP_012493271.1\|1385377_1387237_-\|dihydroxy-acid-dehydratase	unknown	unknown	gnl\|CDD\|237104
NC_011001.1\|WP_006484701.1\|1382084_1383611_-\|sigma-70-family-RNA-polymerase-sigma-factor	unknown	unknown	gnl\|CDD\|274108
NC_011001.1\|WP_006488725.1\|1403525_1403876_+\|helix-turn-helix-transcriptional-regulator	csa3	COG0640_csa3_CAS-I-A	gnl\|CDD\|197713
NC_011001.1\|WP_006488717.1\|1402064_1403426_+\|aromatic-acid/H+-symport-family-MFS-transporter	unknown	unknown	gnl\|CDD\|273327
NC_011001.1\|WP_006488721.1\|1400775_1401984_+\|3-hydroxybenzoate-6-monooxygenase	unknown	unknown	gnl\|CDD\|181262
NC_011001.1\|WP_006488716.1\|1397129_1398074_-\|LysR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|274127
NC_011001.1\|WP_006491049.1\|1390218_1391844_-\|APC-family-permease	unknown	unknown	gnl\|CDD\|223605
NC_011001.1\|WP_012493272.1\|1395810_1397079_+\|NAD(P)/FAD-dependent-oxidoreductase	unknown	unknown	gnl\|CDD\|223523

Protein	Function_ID	Function_description	E-value
NC_011001.1\|WP_006484863.1\|1392069_1392990_-\|dihydrodipicolinate-synthase-family-protein	gnl\|CDD\|188630	cd00408, DHDPS-like, Dihydrodipicolinate synthase family. Dihydrodipicolinate synthase family. A member of the class I aldolases, which use an active-site lysine which stabilizes a reaction intermediate via Schiff base formation, and have TIM beta/alpha barrel fold. The dihydrodipicolinate synthase family comprises several pyruvate-dependent class I aldolases that use the same catalytic step to catalyze different reactions in different pathways and includes such proteins as N-acetylneuraminate lyase, MosA protein, 5-keto-4-deoxy-glucarate dehydratase, trans-o-hydroxybenzylidenepyruvate hydratase-aldolase, trans-2'-carboxybenzalpyruvate hydratase-aldolase, and 2-keto-3-deoxy- gluconate aldolase. The family is also referred to as the N-acetylneuraminate lyase (NAL) family.	1.76599e-97
NC_011001.1\|WP_006491047.1\|1387540_1388563_-\|Ldh-family-oxidoreductase	gnl\|CDD\|224966	COG2055, COG2055, Malate/L-lactate dehydrogenases [Energy production and conversion].	2.72002e-129
NC_011001.1\|WP_006488719.1\|1398237_1399281_+\|gentisate-1,2-dioxygenase	gnl\|CDD\|131325	TIGR02272, gentisate_12-dioxygenase, gentisate 1,2-dioxygenase. This family consists of gentisate 1,2-dioxygenases. This ring-opening enzyme acts in salicylate degradation that goes via gentisate rather than via catechol. It converts gentisate to maleylpyruvate. Some putative gentisate 1,2-dioxygenases are excluded by a relatively high trusted cutoff score because they are too closely related to known examples of 1-hydroxy-2-naphthoate dioxygenase. Therefore some homologs may be bona fide gentisate 1,2-dioxygenases even if they score below the given cutoffs.	0
NC_011001.1\|WP_006488722.1\|1399368_1400067_+\|fumarylacetoacetate-hydrolase-family-protein	gnl\|CDD\|223257	COG0179, MhpD, 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway) [Secondary metabolites biosynthesis, transport, and catabolism].	2.23284e-96
NC_011001.1\|WP_006488711.1\|1400101_1400743_+\|maleylacetoacetate-isomerase	gnl\|CDD\|273527	TIGR01262, Maleylacetoacetate_isomerase, maleylacetoacetate isomerase. Maleylacetoacetate isomerase is an enzyme of tyrosine and phenylalanine catabolism. It requires glutathione and belongs by homology to the zeta family of glutathione S-transferases. The enzyme (EC 5.2.1.2) is described as active also on maleylpyruvate, and the example from a Ralstonia sp. catabolic plasmid is described as a maleylpyruvate isomerase involved in gentisate catabolism. [Energy metabolism, Amino acids and amines].	8.38442e-95
NC_011001.1\|WP_006488726.1\|1403865_1404300_+\|YeeE/YedE-family-protein	gnl\|CDD\|225264	COG2391, COG2391, Predicted transporter component [General function prediction only].	2.10287e-12
NC_011001.1\|WP_006484864.1\|1393241_1394174_+\|4-hydroxyproline-epimerase	gnl\|CDD\|172473	PRK13970, PRK13970, 4-hydroxyproline epimerase.	0
NC_011001.1\|WP_006484690.1\|1383908_1384361_+\|hypothetical-protein	gnl\|CDD\|237864	PRK14950, PRK14950, DNA polymerase III subunits gamma and tau; Provisional.	7.44435e-05
NC_011001.1\|WP_006491351.1\|1395580_1395814_+\|(2Fe-2S)-binding-protein	gnl\|CDD\|379229	pfam13510, Fer2_4, 2Fe-2S iron-sulfur cluster binding domain. The 2Fe-2S ferredoxin family have a general core structure consisting of beta(2)-alpha-beta(2) which a beta-grasp type fold. The domain is around one hundred amino acids with four conserved cysteine residues to which the 2Fe-2S cluster is ligated. This cluster appears within sarcosine oxidase proteins.	1.16336e-17
NC_011001.1\|WP_012493270.1\|1384394_1385258_+\|peptide-binding-protein	gnl\|CDD\|227324	COG4991, COG4991, Uncharacterized protein with a bacterial SH3 domain homologue [Function unknown].	1.17804e-19
NC_011001.1\|WP_006491048.1\|1388555_1390148_-\|aldehyde-dehydrogenase-(NADP(+))	gnl\|CDD\|143447	cd07129, ALDH_KGSADH, Alpha-Ketoglutaric Semialdehyde Dehydrogenase. Alpha-Ketoglutaric Semialdehyde (KGSA) Dehydrogenase (KGSADH, EC 1.2.1.26) catalyzes the NAD(P)+-dependent conversion of KGSA to alpha-ketoglutarate. This CD contains such sequences as those seen in Azospirillum brasilense, KGSADH-II (D-glucarate/D-galactarate-inducible) and KGSADH-III (hydroxy-L-proline-inducible). Both show similar high substrate specificity for KGSA and different coenzyme specificity; KGSADH-II is NAD+-dependent and KGSADH-III is NADP+-dependent. Also included in this CD is the NADP(+)-dependent aldehyde dehydrogenase from Vibrio harveyi which catalyzes the oxidation of long-chain aliphatic aldehydes to acids.	0
NC_011001.1\|WP_006495056.1\|1394170_1395298_+\|FAD-binding-oxidoreductase	gnl\|CDD\|223737	COG0665, DadA, Glycine/D-amino acid oxidases (deaminating) [Amino acid transport and metabolism].	4.85089e-52
NC_011001.1\|WP_012493271.1\|1385377_1387237_-\|dihydroxy-acid-dehydratase	gnl\|CDD\|237104	PRK12448, PRK12448, dihydroxy-acid dehydratase; Provisional.	0
NC_011001.1\|WP_006484701.1\|1382084_1383611_-\|sigma-70-family-RNA-polymerase-sigma-factor	gnl\|CDD\|274108	TIGR02393, RNA_polymerase_sigma_factor_RpoD, RNA polymerase sigma factor RpoD, C-terminal domain. This model represents the well-conserved C-terminal region of the major, essential sigma factor of most bacteria. Members of this clade show considerable variability in domain architecture and molecular weight, as well as in nomenclature: RpoD in E. coli and other Proteobacteria, SigA in Bacillus subtilis and many other Gram-positive bacteria, HrdB in Streptomyces, MysA in Mycobacterium smegmatis, etc. [Transcription, Transcription factors].	2.3011e-88
NC_011001.1\|WP_006488725.1\|1403525_1403876_+\|helix-turn-helix-transcriptional-regulator	gnl\|CDD\|197713	smart00418, HTH_ARSR, helix_turn_helix, Arsenical Resistance Operon Repressor.	2.07261e-17
NC_011001.1\|WP_006488717.1\|1402064_1403426_+\|aromatic-acid/H+-symport-family-MFS-transporter	gnl\|CDD\|273327	TIGR00895, transport_protein, benzoate transport. [Transport and binding proteins, Carbohydrates, organic alcohols, and acids].	2.71938e-107
NC_011001.1\|WP_006488721.1\|1400775_1401984_+\|3-hydroxybenzoate-6-monooxygenase	gnl\|CDD\|181262	PRK08163, PRK08163, 3-hydroxybenzoate 6-monooxygenase.	0
NC_011001.1\|WP_006488716.1\|1397129_1398074_-\|LysR-family-transcriptional-regulator	gnl\|CDD\|274127	TIGR02424, TF_pcaQ, pca operon transcription factor PcaQ. Members of this family are LysR-family transcription factors associated with operons for catabolism of protocatechuate. Members occur only in Proteobacteria. [Energy metabolism, Other, Regulatory functions, DNA interactions].	2.04846e-48
NC_011001.1\|WP_006491049.1\|1390218_1391844_-\|APC-family-permease	gnl\|CDD\|223605	COG0531, PotE, Amino acid transporters [Amino acid transport and metabolism].	4.81968e-51
NC_011001.1\|WP_012493272.1\|1395810_1397079_+\|NAD(P)/FAD-dependent-oxidoreductase	gnl\|CDD\|223523	COG0446, HcaD, Uncharacterized NAD(FAD)-dependent dehydrogenases [General function prediction only].	3.72291e-23

>NC_011001.1|WP_006495056.1|1394170_1395298_+|FAD-binding-oxidoreductase
MSETKTDVVVIGAGIVGAACAHELAQRGLRVLVVDDASGGATGAGMGHLVAMDDNAAELALSHYSIELWRALSGEMPDGCAYRNCGTLWLAADAHEMDLARAKQATLAAHGVAGELIDAAALAQLEPMLRAGLGGALKIPGDAILYAPVTANWLLQRAPRVTVRRERAVAVDGPSVTLASGDVLRAERVVVANGVAARTLLPELPLRPKKGHLLITDRYPGHVSHQLVELGYAASAHASDGTSVAFNVQPRPTGQLLIGSSRQFDTEDAQVEPPVLARMLRRAVGYLPALADLNGIRAWTGFRSASPDGLPLLGEHPARPGVWLAVGHEGLGVTTAPGSARLVAALMAGERPPIEIEPYLPGRFLTASPVAGALT
>NC_011001.1|WP_006484864.1|1393241_1394174_+|4-hydroxyproline-epimerase
MKRIQIIDSHTGGEPTRLVVSGFPSLGDGTMAERRDVLAREHDRYRTACILEPRGSDVLVGALLCDPVAPDAAAGVIFFNNSGYLGMCGHGTIGVVRTLHHMGRIAPGVHRIETPVGTVEATLHDDLSVSVRNVPAYRHAQGVALDVPGYGPVKGDIAWGGNWFFLISDHGQRVAGDNVAALTAYASAVREGLERAGITGANGGEIDHIELFADDPEHDSRSFVLCPGLAYDRSPCGTGTSAKLACLAADGKLAPGAVWRQASVIGSVFHASYERADGGIVPTIRGSAHLSAEATLLIEEDDPFGWGIGS
>NC_011001.1|WP_006484863.1|1392069_1392990_-|dihydrodipicolinate-synthase-family-protein
MSRNAIQWTGVFPAVSTQFKPDFSLDIDATHRVVKNLVNDGVSGLVVCGTVGENTSLSTSEKLQVIEAARDAAGGKIPVIAGIAEFTTEFARNTVREAQRVGVDGVMVMPALVYSAKPHETAAHFRAVATSTDLPVMVYNNPPIYKNDVTPDVLIALQDCENIVCFKDSSGDTRRFIDLRNAVGDRFVLFAGLDDVVVESIAVGAEGWVSGMSNAFPKEGETLFRLAKQKRFDEALALYRWFMPLLHLDARPDLVQCIKLCEELVGRGSAITRPPRLALQGDTLAEVKAIVAKALETRPALPDVGL
>NC_011001.1|WP_006491049.1|1390218_1391844_-|APC-family-permease
MPGQGNAHPSVPLSRSAHPGAGHGKFKKQLSLTDLTFIGLGAIFGSGWLFAASHVSTIAGPAGIFSWLLGGFAVLLLGIVYCELGAALPRAGGVVRYPVFSHGPLLGYLMGFITLIAFSSLIAIEVVAARQYAAAWFPGLTVEGSSDPTTLGWLVQAALLCFFFYLNYSSVKTFAKANNIISIFKFIVPLSVIAVLFTFFKPANLTVHGFAPFGMPGIEMAVSAGGIIFAYLGLTPIVSVASEVRNPQRTIPIALILSILLSTLIYVLLQLAFIGSIPTAMLAAGWHDVSKAFSLPYRDIALALGVGWLAVMVVADAMISPSGCGNIYMNATPRVVYGWAKTGTFFKVFTRVDEASGIPRAGLWLTFGLAIFWTLPFPSWEALINIVSAALVLSYAVAPVSVAALRRTAPDLPRPFRASAFGLTGPASFVIAALIVYWSGWSTVSWLLGLQIVMFAIYLACRRWVPTAHLSLAEQVRSSAWLIAFYAAMIVLSYLGGFGGTGRLAHPYDTVVVAAVALVIYYWGANTGVRTDKLQLDDDED
>NC_011001.1|WP_006491048.1|1388555_1390148_-|aldehyde-dehydrogenase-(NADP(+))
MQLTGQLLIGQSAVAGQNGTLHAIAAATGAPLEPAFGGASLHDLETACALADDAFDTYRETSLDARAAFLDAIGRRIMALGDDLIERCVVETGLPRARIEGERGRTVGQLALFASLVRDGGFLDARIDPARPERKPLPRVDLRLRNVAVGPVAVFGASNFPLAFSVAGGDTASALAAGCPVIVKAHSAHPGTSELVGRAIQQAARECGMPAGVFSLLFDASREIGQALVADPRIKAVGFTGSRRGGVALMHIAAARPEPIPVYAEMSSINPVLLCPAALDARHDAIAPQFVASLTLGAGQFCTNPGLVLAVDGPALRAFESAAADAVRAVAAQTMLTPPIHASYAQGVAALRDHSAVALLAEGVEGGRHQARAALLAASADAFIAHPELRDEVFGPASLIVRCPDTDTLHRVLKSLEGQLTIAAHIADGDAALFAALRPTLERKAGRILVNGFGTGVEVGHAMVHGGPFPATSDTRTTSVGARAIERFLRPVSYQDVPDALLPDAIRSSNPLHVPQRIDGVPAPREVNHG
>NC_011001.1|WP_006491047.1|1387540_1388563_-|Ldh-family-oxidoreductase
MADHTTEVVLSLDEVHALALRVLTHHGMSDAHARAIANVITQGQRDECHSHGVYRLLVCVRSLKKGKVDPQAVPTLRRLSSSIVAVDAHRGFSLLSFETGLPVLVEMAKQHGIAAMAINHCYHFSALWPEVEAIAAEGLVGIAMNPSHSWVAPEGGREPVFGTNPIAFAWPRPGAEPFVFDFATSAIARGDIELHAKQGKAIPSHWAIDADGQPTTDPKAALQGAMRTFGGHKGSALAAMVELLGGALIGDMTSRESMDFDEGVGATPCHGELVIAFDPKVFLGDELDTGLARGERMFESIVAQGARLPSQRRFDARARSIANGVRIPKPLYDEILTLLD
>NC_011001.1|WP_012493271.1|1385377_1387237_-|dihydroxy-acid-dehydratase
MPTYRSKTSTAGRNMAGARSLWRATGMKDDDFSKPIIAVVNSFTQFVPGHVHLKDLGQLVAREIEAAGGVAKEFNTIAVDDGIAMGHDGMLYSLPSRDIIADSVEYMVNAHCADAMVCISNCDKITPGMLMAAMRLNIPVIFVSGGPMEAGKTRLANPVTKTVELKKLDLVDAMVIAADQSYSDADVAEVERSACPTCGSCSGMFTANSMNCLTEALGLSLPGNGTVVATHADREQLFKRAGRRIVELTRQHYEQDDERVLPRSVGFKAFENAMTLDIAMGGSTNTILHLLAIAQEAGIDFTMKDIDRLSRTVPQLCKVAPNTNKYHIEDVHRAGGIMAILGELERAGKLHTDVPTVHAPTLKDALDQWDIVLTQDDAVRTFYLAGPAGIPTQVAFSQNTRWPSLDLDRAEGCIRSYEHAFSKEGGLAVLTGNIALDGCVVKTAGVDESILVFEGSAHVTESQDEAVENILNDKVKAGDVVIVRYEGPKGGPGMQEMLYPTSYIKSKGLGKACALLTDGRFSGGTSGLSIGHCSPEAAAGGAIGLVRDGDRIRIDIPNRTIDVLVSDEELARRREEQNAKGWKPAQPRPRKVSAALKAYAKLVMSADKGAVRDLSLLDD
>NC_011001.1|WP_012493270.1|1384394_1385258_+|peptide-binding-protein
MRNTIVRSLCVVLAGLAAAPGVADAQSSAYTNSPAELFAGPAPDYPVVAQIPPGTALDVFGCLSDYTWCDVALPGVRGWIDAQLLDYPYQGSYVPLLEYGAIIGVPVTGFAIGAYWDRYYRHRPWYPDRDRWAHRAEPRLGPGGMPPAQGRPQPGAPLQVAPGGPPPVHDTRPSATRGGWNGANRVPPPAAPTPAPTPMPGGMGNARPASPAAPTPMPGGAGNARPANPPPAVLHSSPAPGGEGRTMPQPARQGGWGGGGYARPQGGGNGGGNHGGGGGGGPDELRH
>NC_011001.1|WP_006484690.1|1383908_1384361_+|hypothetical-protein
MNPISAARPAVVALAALALGGCYYTSPYGYAPYYAPVPATVTQREIPAAPTAPGPAASTVPQAEVDVGPAVPVYVAPAYVPPPYPYAPYPYAYPAYYSGWYGPPVTIGFWGRWGGGYWGGRGGYWHRPWGGGHWGGGHWGGGHWGGGHRH
>NC_011001.1|WP_006484701.1|1382084_1383611_-|sigma-70-family-RNA-polymerase-sigma-factor
MTTPRPTPRADTPLDPIIQLLALAGEQGYLTHADLVDALPPESDSPDALDVVRAALADIGIAVLDEPAVPAPFAGAAPVEVDRDALDEGRAMLGDLARGTSASTDPLALYMRRMHAVPLLTREGEIVLAREIETGRHQVLHAIAGYPPAVDALLERHRATGTTGSPDDDDADAPVPARYDTLQAAASALREAVHAHGTRSAEYRDARNHVAALLGSLAWVAPAVDDASRVVRALAAAPHDPSAGDAACFDAVARRALAAALSDGQQKVRDATRAMLEANLRLVLSIARKYLNRGVDLSDLVQDGCLGLMRAIEKFEYRRGFKFSTYATWWIRQAIARAVADRSRTIRVPVHVGDQYQRVQRHALRFRQRTGRRATPAELAAETGLAEDKLRAVLALPAEPVSLDTPLPDADTGLVELIEDQASASPFEQLADTRMRDCVRSLLRSVTPTEADVLRRRFGLGGAEPDTYDAIAQDAGMSRERVRQIEKRALAALRTAAEAENAQSFLDA
>NC_011001.1|WP_006491351.1|1395580_1395814_+|(2Fe-2S)-binding-protein
MIIHLDGRALTVADGATVAAAVAASGDDMTRVSCTGAARAPFCGMGICQECRMTIDGRRRLACQTLCRDGMQVERTR
>NC_011001.1|WP_012493272.1|1395810_1397079_+|NAD(P)/FAD-dependent-oxidoreductase
MNQERLSVDVAIVGAGPAGLSAARAAARSGATVAIVDDNPRAGGQIWRQPAASAPTPAAAERLAVLRQPNVTHLAATRIVAETQPGTLLLEDDERGLLLDFRTLILCCGARELLLPFPGWTLPGVTGAGGLQALIKYGLDVRGQRTVIAGSGPLLLASAATARHAGARVSHVLEQAAWGDVAGFGAGLWRWPSKLAQAAKLVTAAYRPAAYVVEAFGDQRLERVRIRQGDREFDVDCDRLACGFGLVPNTVLPRHLGCRIEHGAVAVDAHQRTSRDGYFAAGECTGVGGSELAMVEGEIAGYAATGQTDRLAALVARRARWQAFADAVRERFAIREPIRRLARADTLLCRCEDVRFDAVAREPGWTVAKLQSRCGMGACQGRVCGAAAQALFGWTPPAPRTPLVPARVGTLMLDGTGPCDGA
>NC_011001.1|WP_006488716.1|1397129_1398074_-|LysR-family-transcriptional-regulator
MDWTHRLRLRHLQVLLSLAGTGNLSQSAVALATTQPALSKWLKELEEDVGLPLFERHARGLRPTPYGEALIEHARRVEAQLDIARDDMAALREGGSGLVTIGTSGVAAADTVPFAVSQLLKRMPRAQVRLTESTMNQLMPQLARSELDIVVGRSGSTSVDPLLHAEALYVDPVVFVARPDHALAGATSLGWDDVLAYPWIVWPAGTPVHNALEAALHAAGRAQPPHCVESNSSILNLTLLNNTDLLGVASHRAARRFAQLNAIRILPMELEGQGAVSMYWHPDSANRAAVAATIECLRACAAPQVGGWEKVKVE
>NC_011001.1|WP_006488719.1|1398237_1399281_+|gentisate-1,2-dioxygenase
MTTHPDATRAAYYARIAEQRLAPLWESLHNLVPTSPQPAAQAAIWKYAQIRDLVMQAGSVISAEEAVRRVLVLENPGLPGKSSMTPSLYAGLQLILPGEIAPSHRHTQSALRFIVEGRGAWTAVNGERTTMHPGDFIITPSWAWHDHGNPSVEDGGEPVVWLDGLDIPLLAHLDAGFAENFPEAVQPVNRPEGDSFARFGHNMVPVRHRVSDPTSPVFSYPYARSREALDALYRNGELDAWDGVKLRYVNPATGGWPMPTIATFMQFLPAGFDGRTYRSTDATIYCVVEGRGAALIGDQAFAFAPHDIFVAPSWAPVRLSASSDSVLFSYSDRPVLSALNLLREARD
>NC_011001.1|WP_006488722.1|1399368_1400067_+|fumarylacetoacetate-hydrolase-family-protein
MTFVFPPEAPVALPVAGSDARFAVRRVYCVGRNYAAHAREMGFDPDREPPFFFCKPADSIVPVAYGETLDLAYPSQTQNYHYEAELVAVIGKGGSDIPLERALDHVWGYAVGLDMTRRDLQMKMREMGRPWEIGKAFDRSAPLGPVHRASDVGHVEQGGLWLTVNGATRQKSDVSHLIWSVAETVADLSKFFRLEPGDVIFTGTPEGVGPVVAGDVMKVGVERLGELTVRVV
>NC_011001.1|WP_006488711.1|1400101_1400743_+|maleylacetoacetate-isomerase
MQLHSFFNSSTSYRVRIALALKGLPYDTLPVNIRTGEHRDADYIAQVNPSAAVPALTDDDFRLGQSLAILDYLDQIQPTPRLIPLEPRRRARVLELAALIACDIHPVNNLRVLRYLDSELKVTPQQKSAWYRHWVAEGMAGVERLLARANAGPWCFGDAPTLADVCLVPQVANALRMDCDLSAYPRCLAVVEHARHEPAFEAAQPQRQPDYVA
>NC_011001.1|WP_006488721.1|1400775_1401984_+|3-hydroxybenzoate-6-monooxygenase
MGETINDGRRVLVIGGGIGGLATALALARQGIRVKLLEQAERIGEIGAGIQLAANAFNALDALGVGEAARGRAVLTDWLQLMDAIDAREVARIDTGAAYRDRFGNPYAVIHRADIHLSIYEAVKDHPLIEFRTSTQVCGFEQDGNGVTVIDQHGERYRADAVIGCDGVKSAIRQALIGDAHRVTGHVVYRAVVEVDNMPKDLQINAPVVWAGPHCHLVHYPLRGGRQYNLVVTFHSREQETWGVRDGSKEEVLSYFDGIHPLPKQMLDRPTSWKRWATADRDPVERWSAGRATVLGDAAHPMTQYIAQGACQALEDAVTLGAAVAQTDGDFEAAFALYERVRIPRTARVLYSAREMGRIYHAKGVERQVRNGLWVGRTDAQFYDALDWLHGWRAEDCLKTAA
>NC_011001.1|WP_006488717.1|1402064_1403426_+|aromatic-acid/H+-symport-family-MFS-transporter
MADTLSIDVSEWIDRHRIAPFQAAIVVLCFLIVAIDGFDTASIGFIAPVIRAEWGLSPARLAPVFGAGLAGLMAGALVFGPFGDRFGRKRLLLACVACFGIASAASASAGSLTELIVWRFVTGLGLGGAMPNAITLTSEYCPARRRSLLVTTMFCGFTIGSALGGLAAASLIEHHGWRAVLVVGGAAPLLLLPLLAWRLPESVRYLVNQGAPSARIATMLGRIAPDPHLAHASFIAPAGKPVGSPLGRLFAADLLRGTLLLWLTFFMSLLVIYLLSSWLPTLLRTTGATLQTAARVTAMFQVGGTLGAIILGWLMDRFDPHRVLACSYAAAGACVAAIGVFAASPWGAALAVFAAGFCVSGSQVGANALSAAFYPTECRTTGVSWANGIGRGGSVVGSMAGGAMLAMGVPLSTAFAVVAAPCVIAALAVLALGVVRAGVVRAAAADGMAGRQA
>NC_011001.1|WP_006488725.1|1403525_1403876_+|helix-turn-helix-transcriptional-regulator
MNDDLPAGLPAPDQMRAAAESACALLKVMSNPDRLLLLCELSQGECCVSDLEARLDIHQPTLSQQLGVLRDNALVRTRREGKTIRYSLDSPAVVAVMGVLYEQFCGATAKEARDAG
>NC_011001.1|WP_006488726.1|1403865_1404300_+|YeeE/YedE-family-protein
MQVDALHFTPWLSLAGGVLIGLAAAWLVALNGRIAGISGIVGGLLAAGGAERGWRVAFIAGMIVAPVAMHVAGSSLTPRIDAGWPELLAAGLLVGIGTRYAGGCTSGHGVCGMSRGALRSVVATATFMVAGFATVFVRLHVAGG

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

1138118 : 1184795

Burkholderia_phage(41.86%)

integrase,plate,terminase,capsid

attL 1138581:1138597|attR 1165850:1165866

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_006488884.1\|1138118_1140044_+	selenocysteine-specific translation elongation factor	A0A2K9KZ60	Tupanvirus	4.1e-16	31.5
1138581:1138597	attL	NA	NA	NA	NA
WP_012493219.1\|1140269_1141259_-\|integrase	site-specific integrase	A0A221SAN4	Ralstonia_phage	3.2e-09	33.3
WP_006488850.1\|1141474_1141807_-	hypothetical protein	A9YWU9	Burkholderia_phage	3.0e-12	59.4
WP_006488822.1\|1141803_1142325_-	DUF1643 domain-containing protein	A0A218L3S7	Pseudomonas_phage	2.7e-47	59.8
WP_012493220.1\|1142321_1142789_-	hypothetical protein	NA	NA	NA	NA
WP_012493221.1\|1142805_1143129_-	hypothetical protein	Q5QF38	Pseudomonas_virus	4.7e-10	43.8
WP_012493222.1\|1143125_1143410_-	hypothetical protein	NA	NA	NA	NA
WP_006488909.1\|1143406_1143712_-	hypothetical protein	NA	NA	NA	NA
WP_006488864.1\|1143708_1143951_-	helix-turn-helix domain-containing protein	F8TVE5	EBPR_siphovirus	2.0e-05	43.2
WP_006488915.1\|1143947_1144337_-	hypothetical protein	NA	NA	NA	NA
WP_006488885.1\|1144326_1144620_-	hypothetical protein	NA	NA	NA	NA
WP_012493223.1\|1144612_1145524_-	hypothetical protein	Q3HQW1	Burkholderia_phage	3.1e-06	49.3
WP_006488851.1\|1145507_1146017_-	hypothetical protein	H9C170	Pectobacterium_phage	1.4e-53	60.5
WP_006492894.1\|1146894_1147575_-	YqaJ viral recombinase family protein	A0A0U2BXF3	Paracoccus_phage	6.0e-31	38.5
WP_006488820.1\|1147567_1148425_-	hypothetical protein	A0A2H4J1F0	uncultured_Caudovirales_phage	6.6e-59	60.9
WP_006488837.1\|1148472_1149786_-	hypothetical protein	I6NMK7	Burkholderia_virus	2.5e-17	35.8
WP_006488910.1\|1149946_1150108_-	hypothetical protein	NA	NA	NA	NA
WP_006488853.1\|1150104_1150425_-	hypothetical protein	NA	NA	NA	NA
WP_006488889.1\|1150421_1150811_-	hypothetical protein	Q3HQW8	Burkholderia_phage	6.7e-11	46.7
WP_006488844.1\|1150859_1151096_-	hypothetical protein	NA	NA	NA	NA
WP_006488865.1\|1151160_1151316_-	hypothetical protein	NA	NA	NA	NA
WP_006492886.1\|1151535_1151826_-	hypothetical protein	NA	NA	NA	NA
WP_006488862.1\|1152483_1152867_-	type II toxin-antitoxin system death-on-curing family toxin	A0A222YZ88	Escherichia_phage	3.3e-18	44.8
WP_006488905.1\|1152867_1153044_-	hypothetical protein	NA	NA	NA	NA
WP_012493229.1\|1153137_1154670_-	group II intron reverse transcriptase/maturase	A0A0U4J920	Pseudomonas_phage	2.0e-34	34.5
WP_012493231.1\|1155355_1155760_-	hypothetical protein	NA	NA	NA	NA
WP_034178308.1\|1155843_1156092_+	hypothetical protein	K7PHA1	Enterobacteria_phage	2.6e-16	54.8
WP_006492900.1\|1156295_1156538_-	hypothetical protein	NA	NA	NA	NA
WP_006488823.1\|1156690_1156966_+	hypothetical protein	E5E3P2	Burkholderia_phage	7.3e-20	56.6
WP_006488817.1\|1156950_1157880_+	DUF1376 domain-containing protein	NA	NA	NA	NA
WP_034178303.1\|1157848_1158469_+	hypothetical protein	NA	NA	NA	NA
WP_006488872.1\|1158465_1158936_+	RusA family crossover junction endodeoxyribonuclease	A9YWY9	Burkholderia_phage	1.2e-62	80.1
WP_006488874.1\|1158946_1159276_+	hypothetical protein	A9YWZ0	Burkholderia_phage	7.2e-22	59.2
WP_012493233.1\|1159272_1159866_+	hypothetical protein	A9YWZ1	Burkholderia_phage	1.6e-80	78.4
WP_006492883.1\|1159974_1160154_+	hypothetical protein	NA	NA	NA	NA
WP_012493234.1\|1160234_1160549_+	hypothetical protein	NA	NA	NA	NA
WP_012493235.1\|1160499_1162047_+\|terminase	phage terminase large subunit	H9C0C7	Vibrio_phage	6.0e-111	45.1
WP_006488827.1\|1162043_1163627_+	DUF1073 domain-containing protein	A0A0P0I486	Acinetobacter_phage	5.0e-153	61.7
WP_143274665.1\|1163556_1164207_+\|capsid	minor capsid protein	A9YWZ8	Burkholderia_phage	2.7e-89	76.3
WP_006488880.1\|1164208_1165525_+	DUF2213 domain-containing protein	A0A0P0IRE1	Acinetobacter_phage	1.1e-73	47.6
WP_006488861.1\|1165537_1166026_+	hypothetical protein	A0A0P0I8F3	Acinetobacter_phage	1.4e-37	56.2
1165850:1165866	attR	NA	NA	NA	NA
WP_006488835.1\|1166036_1167074_+	DUF2184 domain-containing protein	A0A0N7IRF2	Acinetobacter_phage	1.7e-125	67.7
WP_006488891.1\|1167083_1167509_+	hypothetical protein	A0A2H4J9M7	uncultured_Caudovirales_phage	7.9e-05	40.5
WP_006488870.1\|1167564_1167948_+	DUF4054 domain-containing protein	A9YX25	Burkholderia_phage	9.1e-53	75.6
WP_006488871.1\|1167976_1168459_+	hypothetical protein	A9YX26	Burkholderia_phage	1.9e-71	86.2
WP_006488908.1\|1168462_1168834_+	hypothetical protein	A9YX28	Burkholderia_phage	1.3e-59	89.4
WP_006488819.1\|1168838_1169429_+	hypothetical protein	A9YX29	Burkholderia_phage	5.1e-95	86.7
WP_006488916.1\|1169438_1171250_+	DUF3383 family protein	A0A0P0I492	Acinetobacter_phage	2.0e-89	37.6
WP_006488900.1\|1171267_1171708_+	DUF3277 family protein	A0A0P0IKY2	Acinetobacter_phage	1.4e-41	58.2
WP_006488838.1\|1171710_1172163_+	hypothetical protein	A0A0N7IRF3	Acinetobacter_phage	3.5e-19	37.0
WP_006488906.1\|1172159_1172345_+	hypothetical protein	NA	NA	NA	NA
WP_006488896.1\|1172337_1174125_+	glucosaminidase domain-containing protein	A0A0M4REK7	Salmonella_phage	9.9e-25	33.7
WP_006488828.1\|1174121_1174727_+	hypothetical protein	A0A0P0IKS1	Acinetobacter_phage	2.6e-17	37.1
WP_006488856.1\|1174726_1175041_+	hypothetical protein	A0A0M4R5B7	Salmonella_phage	3.3e-16	48.4
WP_143284610.1\|1175303_1175537_+	hypothetical protein	NA	NA	NA	NA
WP_006488877.1\|1175706_1176684_+	hypothetical protein	A9YX04	Burkholderia_phage	3.1e-97	60.0
WP_006488811.1\|1176680_1177094_-	hypothetical protein	NA	NA	NA	NA
WP_006488810.1\|1177107_1177899_+	hypothetical protein	A9YX06	Burkholderia_phage	7.6e-70	53.6
WP_006488821.1\|1177906_1178257_+	hypothetical protein	A9YX11	Burkholderia_phage	7.6e-38	70.9
WP_006488913.1\|1178253_1179441_+\|plate	baseplate J/gp47 family protein	A9YX12	Burkholderia_phage	8.9e-147	69.4
WP_006488854.1\|1179442_1180159_+	DUF2612 domain-containing protein	A9YX13	Burkholderia_phage	4.2e-75	62.0
WP_006488881.1\|1180215_1181214_+	hypothetical protein	A9YX14	Burkholderia_phage	3.0e-31	42.2
WP_006488895.1\|1181229_1181808_+	hypothetical protein	NA	NA	NA	NA
WP_006488897.1\|1181825_1183382_+	pectate lyase	NA	NA	NA	NA
WP_006488833.1\|1183385_1183778_+	hypothetical protein	NA	NA	NA	NA
WP_006488859.1\|1184090_1184795_+	chitinase class I domain protein	A0A059VA40	Pseudomonas_phage	2.4e-27	41.7

DBSCAN-SWA_2

2103273 : 2136490

Escherichia_phage(55.56%)

integrase,plate,transposase,terminase

attL 2120246:2120260|attR 2142425:2142439

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_006483923.1\|2103273_2104215_+\|terminase	terminase small subunit	Q6V7Q7	Burkholderia_virus	6.2e-18	29.4
WP_012493420.1\|2104189_2105500_+\|terminase	putative phage terminase large subunit	NA	NA	NA	NA
WP_006483920.1\|2105509_2106970_+	hypothetical protein	A0A0U2S5X9	Escherichia_phage	4.6e-52	31.3
WP_006483917.1\|2107546_2107984_+	hypothetical protein	NA	NA	NA	NA
WP_127837577.1\|2108249_2108981_+	hypothetical protein	NA	NA	NA	NA
WP_006483930.1\|2109002_2109779_+	hypothetical protein	NA	NA	NA	NA
WP_006483941.1\|2109902_2110448_+	hypothetical protein	NA	NA	NA	NA
WP_006483925.1\|2110577_2111600_+	hypothetical protein	NA	NA	NA	NA
WP_006483921.1\|2111795_2112299_+	hypothetical protein	NA	NA	NA	NA
WP_006493766.1\|2112338_2112809_+	hypothetical protein	NA	NA	NA	NA
WP_006483932.1\|2112941_2113262_+	hypothetical protein	NA	NA	NA	NA
WP_006483949.1\|2113406_2114039_+	hypothetical protein	NA	NA	NA	NA
WP_006483915.1\|2114618_2115107_+	hypothetical protein	NA	NA	NA	NA
WP_006483914.1\|2115236_2116589_+	hypothetical protein	A0A0U2KD19	Escherichia_phage	4.7e-51	32.7
WP_012493428.1\|2116679_2117120_+	hypothetical protein	A0A0U2S616	Escherichia_phage	2.8e-21	37.3
WP_012493429.1\|2117201_2117735_+	hypothetical protein	NA	NA	NA	NA
WP_006483947.1\|2117890_2119933_+	hypothetical protein	NA	NA	NA	NA
WP_085964393.1\|2120048_2120865_+\|transposase	IS5-like element IS402 family transposase	A0A0N9SHJ4	Paenibacillus_phage	1.5e-07	35.0
2120246:2120260	attL	NA	NA	NA	NA
WP_012493432.1\|2120892_2121555_+	hypothetical protein	NA	NA	NA	NA
WP_012493433.1\|2121564_2121852_+	hypothetical protein	NA	NA	NA	NA
WP_012493434.1\|2121856_2123032_+	hypothetical protein	NA	NA	NA	NA
WP_012493435.1\|2123033_2123459_+	hypothetical protein	A0A0U2RTA8	Escherichia_phage	3.6e-10	34.9
WP_077181431.1\|2123576_2123891_+	hypothetical protein	NA	NA	NA	NA
WP_012493437.1\|2123894_2125103_+\|plate	baseplate J/gp47 family protein	A0A0U2RJZ0	Escherichia_phage	4.8e-55	34.2
WP_006483926.1\|2125173_2126739_+	SPRY domain protein	NA	NA	NA	NA
WP_102896096.1\|2128809_2129929_+\|transposase	IS3 family transposase	S5WIU1	Leptospira_phage	2.1e-49	39.9
WP_006482779.1\|2130014_2131601_+	hypothetical protein	C5IHQ4	Burkholderia_virus	2.2e-15	58.0
WP_006482782.1\|2131576_2132182_+	lysozyme	NA	NA	NA	NA
WP_034178565.1\|2132195_2132411_+	hypothetical protein	NA	NA	NA	NA
WP_012493440.1\|2132495_2132912_-	DUF4279 domain-containing protein	NA	NA	NA	NA
WP_012493441.1\|2132918_2133680_-	hypothetical protein	NA	NA	NA	NA
WP_006482778.1\|2133743_2134412_-	hypothetical protein	NA	NA	NA	NA
WP_127837578.1\|2134948_2135443_+	replication/maintenance protein RepL	NA	NA	NA	NA
WP_127837579.1\|2135677_2136490_-\|integrase	tyrosine-type recombinase/integrase	NA	NA	NA	NA
2142425:2142439	attR	NA	NA	NA	NA

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

3. NC_011002

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

573365 : 609590

Burkholderia_phage(90.2%)

capsid,plate,tail,integrase,transposase,holin

attL 591524:591540|attR 608050:608066

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_006485378.1\|573365_574499_+	acyltransferase	Q6QI96	Burkholderia_phage	3.6e-214	100.0
WP_006485406.1\|574699_577057_-	hypothetical protein	Q6QI97	Burkholderia_phage	0.0e+00	100.0
WP_012493761.1\|577056_577638_-\|tail	phage tail protein I	Q6QI98	Burkholderia_phage	1.4e-105	100.0
WP_006485373.1\|577630_578782_-\|plate	baseplate J/gp47 family protein	Q6QI99	Burkholderia_phage	2.7e-209	99.7
WP_006485365.1\|578778_579132_-	GPW/gp25 family protein	Q6QIA0	Burkholderia_phage	6.9e-63	100.0
WP_006485402.1\|579185_579788_-\|plate	phage baseplate assembly protein V	Q6QIA1	Burkholderia_phage	8.1e-88	100.0
WP_006485372.1\|579784_580990_-	phage late control D family protein	Q6QIA2	Burkholderia_phage	2.0e-218	100.0
WP_006485366.1\|580977_581187_-\|tail	tail protein X	Q6QIA3	Burkholderia_phage	4.4e-33	100.0
WP_006485408.1\|581186_582077_-\|tail	phage tail protein	Q6QIA4	Burkholderia_phage	8.8e-107	100.0
WP_006485356.1\|582078_584619_-\|tail	phage tail tape measure protein	A4JWL0	Burkholderia_virus	0.0e+00	91.8
WP_006485393.1\|584648_584891_+	hypothetical protein	A4JWK9	Burkholderia_virus	4.6e-34	96.2
WP_012493763.1\|584893_585097_-	hypothetical protein	Q6QIA7	Burkholderia_phage	3.4e-30	100.0
WP_006485398.1\|585023_585353_-\|tail	phage tail assembly protein	Q6QIA8	Burkholderia_phage	6.2e-50	100.0
WP_006485397.1\|585474_585999_-\|tail	phage major tail tube protein	Q6QIA9	Burkholderia_phage	5.9e-95	100.0
WP_006485369.1\|586001_587435_-\|tail	phage tail sheath subtilisin-like domain-containing protein	A4JWK5	Burkholderia_virus	2.6e-270	98.7
WP_006485405.1\|587438_587684_-	hypothetical protein	Q6QIB1	Burkholderia_phage	3.1e-38	100.0
WP_006485353.1\|587680_588145_-	Gp37 family protein	Q6QIB2	Burkholderia_phage	3.0e-82	100.0
WP_006485358.1\|588144_588597_-	DUF1320 domain-containing protein	Q6QIB3	Burkholderia_phage	5.5e-81	100.0
WP_006485381.1\|588598_588931_-	DUF2190 family protein	Q6QIB4	Burkholderia_phage	3.0e-52	100.0
WP_006485371.1\|589005_589929_-	hypothetical protein	A4JWK0	Burkholderia_virus	5.6e-165	95.1
WP_006485410.1\|589974_591093_-	hypothetical protein	Q6QIB7	Burkholderia_phage	2.3e-213	100.0
WP_034178535.1\|591307_591841_-	phage virion morphogenesis protein	Q6QIB8	Burkholderia_phage	4.8e-92	99.4
591524:591540	attL	NA	NA	NA	NA
WP_006485383.1\|591831_592668_-\|capsid	minor capsid protein	Q6QIB9	Burkholderia_phage	2.7e-166	100.0
WP_006485375.1\|592660_594136_-	DUF935 domain-containing protein	Q6QIC0	Burkholderia_phage	1.3e-285	100.0
WP_006485377.1\|594132_595635_-	hypothetical protein	Q6QIC1	Burkholderia_phage	6.1e-294	100.0
WP_006485391.1\|595631_596177_-	DUF3486 family protein	Q6QIC2	Burkholderia_phage	8.6e-89	100.0
WP_006485389.1\|596178_596511_-	hypothetical protein	Q6QIC3	Burkholderia_phage	8.7e-60	100.0
WP_006485409.1\|596507_596846_-	hypothetical protein	Q6QIC4	Burkholderia_phage	2.1e-53	100.0
WP_006485363.1\|596842_597442_-	hypothetical protein	Q6QIC6	Burkholderia_phage	9.8e-94	100.0
WP_006485414.1\|597438_598050_-	transglycosylase SLT domain-containing protein	Q6QIC7	Burkholderia_phage	7.4e-113	100.0
WP_006485400.1\|598052_598400_-\|holin	putative holin	Q6QIC8	Burkholderia_phage	8.0e-56	100.0
WP_006485403.1\|598466_598691_-	hypothetical protein	Q6QIC9	Burkholderia_phage	8.5e-35	100.0
WP_006485413.1\|598755_599292_-	hypothetical protein	Q6QID0	Burkholderia_phage	6.7e-94	100.0
WP_006485386.1\|599272_599461_-	hypothetical protein	A4JWP0	Burkholderia_virus	3.3e-24	93.5
WP_006485360.1\|599533_600316_-	hypothetical protein	Q6QID1	Burkholderia_phage	1.3e-143	100.0
WP_012493766.1\|600312_600729_-	helix-turn-helix transcriptional regulator	Q6QID2	Burkholderia_phage	7.1e-67	100.0
WP_006485399.1\|600856_601099_+	DNA-binding protein	Q6QID3	Burkholderia_phage	4.4e-37	100.0
WP_012493768.1\|601147_601384_-	hypothetical protein	Q6QID5	Burkholderia_phage	3.6e-36	100.0
WP_012493770.1\|601504_601984_+	hypothetical protein	Q6QID6	Burkholderia_phage	2.9e-88	100.0
WP_006485394.1\|601980_602283_+	helix-turn-helix domain-containing protein	Q6QID7	Burkholderia_phage	7.0e-48	100.0
WP_012493771.1\|602293_602506_+	hypothetical protein	Q6QID8	Burkholderia_phage	2.2e-32	100.0
WP_006485380.1\|602516_603470_+	hypothetical protein	Q6QID9	Burkholderia_phage	3.9e-169	100.0
WP_006485354.1\|603487_605287_+\|integrase,transposase	DDE-type integrase/transposase/recombinase	Q6QIE0	Burkholderia_phage	0.0e+00	100.0
WP_034178537.1\|605286_606498_+	AAA family ATPase	Q6QIE1	Burkholderia_phage	1.2e-223	100.0
WP_006485359.1\|606499_606829_+	hypothetical protein	Q6QIE2	Burkholderia_phage	4.4e-56	100.0
WP_012493772.1\|606864_607287_+	hypothetical protein	Q6QIE3	Burkholderia_phage	5.9e-77	100.0
WP_006485364.1\|607409_608027_+	DUF3164 family protein	Q6QIE4	Burkholderia_phage	1.3e-112	100.0
WP_006485362.1\|608090_608363_+	HU family DNA-binding protein	Q6QIE5	Burkholderia_phage	6.7e-42	100.0
608050:608066	attR	NA	NA	NA	NA
WP_006485374.1\|608393_608798_+	DUF2528 family protein	Q6QIE6	Burkholderia_phage	4.9e-73	100.0
WP_006485388.1\|608781_609222_+	regulatory protein GemA	Q6QIE7	Burkholderia_phage	3.0e-76	100.0
WP_006485401.1\|609218_609590_+	DNA-binding protein	Q6QIE8	Burkholderia_phage	8.5e-64	100.0

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

4. NC_011000

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

60763 : 171004

Burkholderia_phage(61.11%)

integrase,holin,plate,tail,transposase

attL 100330:100360|attR 125266:125296

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_012492245.1\|60763_61783_+\|transposase	IS110-like element ISBcen5 family transposase	NA	NA	NA	NA
WP_006488477.1\|62069_62858_+	ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_006491543.1\|62873_64304_+	FAD-binding oxidoreductase	NA	NA	NA	NA
WP_006490876.1\|64349_64922_-	PadR family transcriptional regulator	NA	NA	NA	NA
WP_006490878.1\|64990_65422_-	Cd(II)/Pb(II)-responsive transcriptional regulator	NA	NA	NA	NA
WP_012492246.1\|65503_68044_+	heavy metal translocating P-type ATPase	E4ZFI9	Streptococcus_phage	3.1e-133	45.3
WP_006489530.1\|68054_68432_+	zinc ribbon domain-containing protein	NA	NA	NA	NA
WP_012492247.1\|68590_69472_-	AraC family transcriptional regulator	NA	NA	NA	NA
WP_012492248.1\|69747_71211_+	mechanosensitive ion channel	NA	NA	NA	NA
WP_006489522.1\|71400_72813_+	ethanolamine permease	NA	NA	NA	NA
WP_006489528.1\|72952_74350_+	ethanolamine ammonia-lyase subunit EutB	NA	NA	NA	NA
WP_006489519.1\|74346_75144_+	ethanolamine ammonia-lyase subunit EutC	NA	NA	NA	NA
WP_012492249.1\|75136_76021_-	LysR family transcriptional regulator	NA	NA	NA	NA
WP_020979463.1\|76176_77799_+	MFS transporter	NA	NA	NA	NA
WP_034178592.1\|77941_78370_-	pyridoxamine 5'-phosphate oxidase family protein	NA	NA	NA	NA
WP_006489874.1\|78691_80218_+	aldehyde dehydrogenase	NA	NA	NA	NA
WP_006489872.1\|80394_80943_+	hypothetical protein	NA	NA	NA	NA
WP_006493582.1\|81148_82165_+	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_006483320.1\|82259_83357_-	hypothetical protein	NA	NA	NA	NA
WP_012492253.1\|83353_85057_-	thiamine pyrophosphate-binding protein	NA	NA	NA	NA
WP_006485674.1\|85335_85797_+	hypothetical protein	NA	NA	NA	NA
WP_006485672.1\|85793_86078_+	type II toxin-antitoxin system mRNA interferase toxin, RelE/StbE family	NA	NA	NA	NA
WP_006485681.1\|86235_87624_-	L-serine ammonia-lyase	NA	NA	NA	NA
WP_006485680.1\|87654_88797_-	alginate lyase family protein	NA	NA	NA	NA
WP_006485677.1\|88948_91876_-	aminomethyl-transferring glycine dehydrogenase	M4QFZ1	Prochlorococcus_phage	6.2e-258	51.0
WP_006485673.1\|91934_92315_-	glycine cleavage system protein GcvH	NA	NA	NA	NA
WP_006485675.1\|92441_93560_-	glycine cleavage system aminomethyltransferase GcvT	NA	NA	NA	NA
WP_006485676.1\|94027_94390_-	hypothetical protein	NA	NA	NA	NA
WP_006485682.1\|94593_95646_-	oxidoreductase	NA	NA	NA	NA
WP_006496277.1\|95947_96655_-	SGNH/GDSL hydrolase family protein	NA	NA	NA	NA
WP_012492254.1\|96965_99053_+	UvrD-helicase domain-containing protein	A7KV33	Bacillus_phage	1.8e-102	35.7
WP_006496275.1\|99159_100047_-	cytochrome c5 family protein	NA	NA	NA	NA
100330:100360	attL	NA	NA	NA	NA
WP_006484045.1\|100428_101505_-\|integrase	site-specific integrase	A0A1S5NNJ1	Burkholderia_phage	7.2e-164	81.7
WP_034178513.1\|101507_101780_+	hypothetical protein	NA	NA	NA	NA
WP_006484046.1\|102199_104992_-	toprim domain-containing protein	E5E3N5	Burkholderia_phage	0.0e+00	90.9
WP_006493879.1\|104997_105255_-	hypothetical protein	A4JWQ9	Burkholderia_virus	7.3e-14	57.1
WP_006485448.1\|105382_105631_-	ogr/Delta-like zinc finger family protein	K4PAZ0	Burkholderia_phage	3.5e-37	91.5
WP_006485450.1\|105812_106028_-	hypothetical protein	E5E3U1	Burkholderia_phage	4.4e-20	80.0
WP_077176263.1\|106154_106610_+	helix-turn-helix transcriptional regulator	E5E3U2	Burkholderia_phage	7.0e-44	62.3
WP_012492258.1\|107181_108714_+	group II intron reverse transcriptase/maturase	A0A0U4J920	Pseudomonas_phage	2.0e-34	34.5
WP_006485449.1\|108841_109138_+	hypothetical protein	E5E3U3	Burkholderia_phage	1.6e-12	50.5
WP_006485451.1\|109325_110396_-	phage late control D family protein	K4PAY4	Burkholderia_phage	1.1e-135	70.6
WP_006485447.1\|110392_110824_-\|tail	phage tail protein	K4NXK5	Burkholderia_phage	8.2e-42	67.4
WP_012492260.1\|110846_113417_-	hypothetical protein	E5E3U6	Burkholderia_phage	2.2e-134	46.7
WP_006484104.1\|113432_113546_-\|tail	GpE family phage tail protein	A0A089FGX3	Burkholderia_phage	1.1e-09	85.7
WP_171984197.1\|113554_113890_-\|tail	phage tail assembly protein	K4NXA3	Burkholderia_phage	1.5e-27	65.5
WP_006484101.1\|114002_114512_-\|tail	phage major tail tube protein	E5E3U9	Burkholderia_phage	1.5e-71	74.6
WP_006484096.1\|114540_115713_-\|tail	phage tail sheath protein	A4JWS7	Burkholderia_virus	3.0e-187	81.7
WP_006484105.1\|115767_116502_-\|tail	tail assembly chaperone	E5E3V1	Burkholderia_phage	1.8e-89	84.2
WP_006484087.1\|116517_119169_-\|tail	tail fiber protein	E5E3V2	Burkholderia_phage	0.0e+00	71.3
WP_006484097.1\|119175_119718_-\|tail	phage tail protein I	E5FFH2	Burkholderia_phage	5.2e-70	70.9
WP_006484106.1\|119710_120625_-\|plate	baseplate J/gp47 family protein	E5FFH3	Burkholderia_phage	1.5e-117	72.6
WP_006484088.1\|120621_120984_-	GPW/gp25 family protein	K4PAX6	Burkholderia_phage	2.6e-41	69.2
WP_006484112.1\|120980_121667_-\|plate	phage baseplate assembly protein V	K4NXJ5	Burkholderia_phage	2.0e-82	69.2
WP_006484113.1\|122175_122625_-\|tail	phage tail protein	E5E3V9	Burkholderia_phage	1.5e-30	54.2
WP_006484109.1\|122741_123182_-	protein lysB	K4NXJ2	Burkholderia_phage	1.4e-17	44.4
WP_006484095.1\|123178_124036_-	DUF3380 domain-containing protein	A4JWZ0	Burkholderia_virus	1.7e-91	65.8
WP_006484102.1\|124032_124299_-\|holin	phage holin family protein	E5E3W3	Burkholderia_phage	6.2e-24	65.5
WP_006484093.1\|124300_124645_-	membrane protein	A4JWU2	Burkholderia_virus	5.7e-38	77.9
WP_006484103.1\|124661_124868_-\|tail	tail protein X	E5E3W5	Burkholderia_phage	5.1e-18	64.7
WP_006484107.1\|125429_127049_+	TIGR04222 domain-containing membrane protein	NA	NA	NA	NA
125266:125296	attR	NA	NA	NA	NA
WP_034178448.1\|127288_129232_+	glycosyltransferase family protein	NA	NA	NA	NA
WP_006484098.1\|129386_130529_-	DegT/DnrJ/EryC1/StrS family aminotransferase	A0A0P0CNN6	Ostreococcus_mediterraneus_virus	2.5e-13	24.4
WP_006484115.1\|130558_132901_-	tetratricopeptide repeat protein	NA	NA	NA	NA
WP_006484091.1\|133157_133457_-	flagellar protein FliT	NA	NA	NA	NA
WP_006484094.1\|133482_134991_-	flagellar filament capping protein FliD	NA	NA	NA	NA
WP_006484100.1\|135123_136278_-	flagellin	NA	NA	NA	NA
WP_006401410.1\|136808_137021_+	30S ribosomal protein S21	NA	NA	NA	NA
WP_006484092.1\|137187_139311_-	TonB-dependent receptor	NA	NA	NA	NA
WP_006484111.1\|139540_140776_+	PepSY domain-containing protein	NA	NA	NA	NA
WP_006489711.1\|140860_141463_-	DNA-3-methyladenine glycosylase I	NA	NA	NA	NA
WP_012492265.1\|141604_142486_+	ATPase	NA	NA	NA	NA
WP_006489316.1\|142625_143450_+	Cof-type HAD-IIB family hydrolase	NA	NA	NA	NA
WP_006489324.1\|143589_144333_-	aquaporin Z	A0A1B1ISL4	uncultured_Mediterranean_phage	8.1e-05	50.8
WP_006489320.1\|144632_144929_+	H-NS histone family protein	F8TUP5	EBPR_podovirus	1.9e-10	41.1
WP_006489318.1\|145032_146097_-	glycosyltransferase family 4 protein	NA	NA	NA	NA
WP_162470859.1\|146412_146763_-	hypothetical protein	NA	NA	NA	NA
WP_006477348.1\|146728_147082_+	flagellar transcriptional regulator FlhD	NA	NA	NA	NA
WP_006493184.1\|147174_147729_+	flagellar transcriptional regulator FlhC	NA	NA	NA	NA
WP_006482649.1\|147909_148770_+	flagellar motor stator protein MotA	NA	NA	NA	NA
WP_006482647.1\|148783_149803_+	flagellar motor protein MotB	NA	NA	NA	NA
WP_006482646.1\|149827_150205_+	response regulator	NA	NA	NA	NA
WP_012492266.1\|150238_152506_+	chemotaxis protein CheA	NA	NA	NA	NA
WP_006486165.1\|152553_153069_+	chemotaxis protein CheW	NA	NA	NA	NA
WP_012492267.1\|153106_155065_+	Tar ligand binding domain-containing protein	A0A2H4J162	uncultured_Caudovirales_phage	1.4e-11	41.7
WP_006493442.1\|155068_156061_+	chemotaxis protein CheR	NA	NA	NA	NA
WP_006497454.1\|156057_156816_+	chemoreceptor glutamine deamidase CheD	NA	NA	NA	NA
WP_012492268.1\|156812_157904_+	chemotaxis response regulator protein-glutamate methylesterase	NA	NA	NA	NA
WP_006485893.1\|157971_158367_+	chemotaxis response regulator CheY	Q56AR1	Bacillus_thuringiensis_phage	6.0e-07	31.9
WP_006485885.1\|158369_159101_+	protein phosphatase CheZ	NA	NA	NA	NA
WP_012492269.1\|159360_159864_+	DUF2844 domain-containing protein	NA	NA	NA	NA
WP_006485888.1\|161282_161780_+	VOC family protein	NA	NA	NA	NA
WP_006485884.1\|162209_163409_+	flagellar type III secretion system protein FlhB	NA	NA	NA	NA
WP_006485892.1\|163405_165508_+	flagellar biosynthesis protein FlhA	NA	NA	NA	NA
WP_012492270.1\|165504_167304_+	flagellar biosynthesis protein FlhF	NA	NA	NA	NA
WP_006491878.1\|167296_168115_+	flagellar biosynthesis protein FlhG	NA	NA	NA	NA
WP_006484033.1\|168137_168872_+	RNA polymerase sigma factor FliA	NA	NA	NA	NA
WP_006484031.1\|169123_170542_+	adenosylhomocysteinase	S4VPF6	Pandoravirus	9.9e-44	30.1
WP_006477367.1\|170650_171004_+\|holin	phage holin family protein	NA	NA	NA	NA

DBSCAN-SWA_2

316768 : 373024

uncultured_Mediterranean_phage(40.0%)

transposase,plate,protease

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_006490629.1\|316768_317482_+\|transposase	transposase	NA	NA	NA	NA
WP_006490631.1\|317770_322474_+	glutamate synthase subunit alpha	NA	NA	NA	NA
WP_006490625.1\|322559_324026_+	glutamate synthase subunit beta	NA	NA	NA	NA
WP_006490627.1\|324401_325892_+	alanine:cation symporter family protein	NA	NA	NA	NA
WP_012492302.1\|325888_326455_+	RNA 2',3'-cyclic phosphodiesterase	NA	NA	NA	NA
WP_006482643.1\|326487_327771_-	D-amino acid dehydrogenase	NA	NA	NA	NA
WP_006482644.1\|327796_329059_-	MFS transporter	NA	NA	NA	NA
WP_012492303.1\|329187_329964_-	SDR family oxidoreductase	NA	NA	NA	NA
WP_006488528.1\|329960_331730_-	ABC transporter ATP-binding protein/permease	NA	NA	NA	NA
WP_006488532.1\|332349_333486_+	FAD-dependent oxidoreductase	NA	NA	NA	NA
WP_006488534.1\|333518_333716_+	sulfur carrier protein ThiS	NA	NA	NA	NA
WP_006488530.1\|333754_334570_+	thiazole synthase	NA	NA	NA	NA
WP_012492304.1\|334566_335691_+	thiamine phosphate synthase	NA	NA	NA	NA
WP_006477138.1\|335775_336597_+	ABC transporter ATP-binding protein	G3M9Y6	Bacillus_virus	3.1e-21	29.4
WP_006486220.1\|336593_337361_+	lipid asymmetry maintenance ABC transporter permease subunit MlaE	NA	NA	NA	NA
WP_006486221.1\|337385_337946_+	outer membrane lipid asymmetry maintenance protein MlaD	NA	NA	NA	NA
WP_020979879.1\|337977_338940_+	VacJ family lipoprotein	NA	NA	NA	NA
WP_012492305.1\|339051_339681_+	ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_006485329.1\|339677_339953_+	STAS domain-containing protein	NA	NA	NA	NA
WP_006485348.1\|340145_341072_+	ABC transporter ATP-binding protein	A0A2H4PQG7	Staphylococcus_phage	8.2e-23	30.2
WP_023476193.1\|341128_341890_+	ABC transporter permease	NA	NA	NA	NA
WP_006477131.1\|341943_342183_+	BolA family transcriptional regulator	NA	NA	NA	NA
WP_006485350.1\|342197_343547_+	UDP-N-acetylglucosamine 1-carboxyvinyltransferase	NA	NA	NA	NA
WP_006477129.1\|343543_344197_+	ATP phosphoribosyltransferase	NA	NA	NA	NA
WP_006485330.1\|344221_345538_+	histidinol dehydrogenase	NA	NA	NA	NA
WP_006485351.1\|345636_346710_+	histidinol-phosphate transaminase	NA	NA	NA	NA
WP_006477126.1\|346775_347363_+	imidazoleglycerol-phosphate dehydratase HisB	NA	NA	NA	NA
WP_006485349.1\|347424_348045_+	YchE family NAAT transporter	NA	NA	NA	NA
WP_012492306.1\|348041_348683_+	imidazole glycerol phosphate synthase subunit HisH	NA	NA	NA	NA
WP_006477123.1\|348846_349602_+	1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino]imidazole-4- carboxamide isomerase	NA	NA	NA	NA
WP_006485327.1\|349708_350482_+	imidazole glycerol phosphate synthase subunit HisF	NA	NA	NA	NA
WP_012492307.1\|350481_350898_+	phosphoribosyl-AMP cyclohydrolase	NA	NA	NA	NA
WP_006485344.1\|350894_351260_+	phosphoribosyl-ATP diphosphatase	NA	NA	NA	NA
WP_006485332.1\|351330_351723_+	membrane protein	NA	NA	NA	NA
WP_006485352.1\|351754_352120_+	histidine triad nucleotide-binding protein	NA	NA	NA	NA
WP_006477115.1\|352213_352444_+	Sec-independent protein translocase subunit TatA	NA	NA	NA	NA
WP_006485331.1\|352470_353010_+	Sec-independent protein translocase subunit TatB	NA	NA	NA	NA
WP_006485341.1\|353051_353840_+	twin-arginine translocase subunit TatC	A0A1B1IVR7	uncultured_Mediterranean_phage	1.8e-26	29.8
WP_006485345.1\|354049_355255_-	Do family serine endopeptidase	A0A1B1IRD3	uncultured_Mediterranean_phage	1.9e-11	34.3
WP_006485336.1\|355276_356023_+	Nif3-like dinuclear metal center hexameric protein	NA	NA	NA	NA
WP_006491868.1\|356241_356862_+	ubiquinol-cytochrome c reductase iron-sulfur subunit	NA	NA	NA	NA
WP_006485333.1\|356861_358244_+	cytochrome bc complex cytochrome b subunit	NA	NA	NA	NA
WP_006477108.1\|358265_359024_+	cytochrome c1	NA	NA	NA	NA
WP_006400565.1\|359118_359730_+	glutathione S-transferase N-terminal domain-containing protein	NA	NA	NA	NA
WP_006485328.1\|359801_360323_+\|protease	ClpXP protease specificity-enhancing factor	A0A1S5R3H3	Pseudomonas_phage	9.6e-21	52.0
WP_006485326.1\|360771_360975_+	hypothetical protein	NA	NA	NA	NA
WP_006485337.1\|361084_361885_-	transporter substrate-binding domain-containing protein	NA	NA	NA	NA
WP_006485338.1\|362166_362484_+	hypothetical protein	NA	NA	NA	NA
WP_006485334.1\|362565_362901_+	hypothetical protein	NA	NA	NA	NA
WP_006491869.1\|363014_363797_-	DotU family type IV/VI secretion system protein	NA	NA	NA	NA
WP_006477098.1\|363793_365140_-\|plate	type VI secretion system baseplate subunit TssK	NA	NA	NA	NA
WP_006485335.1\|365245_365845_-	type VI secretion system lipoprotein TssJ	NA	NA	NA	NA
WP_012492309.1\|366231_366858_+	hypothetical protein	NA	NA	NA	NA
WP_006484395.1\|366904_367420_+	type VI secretion system contractile sheath small subunit	NA	NA	NA	NA
WP_006484397.1\|367435_368926_+	type VI secretion system contractile sheath large subunit	NA	NA	NA	NA
WP_006477093.1\|368996_369500_+	type VI secretion system tube protein Hcp	NA	NA	NA	NA
WP_006477092.1\|369562_370048_+\|plate	type VI secretion system baseplate subunit TssE	NA	NA	NA	NA
WP_006484396.1\|370124_371960_+\|plate	type VI secretion system baseplate subunit TssF	NA	NA	NA	NA
WP_006484394.1\|371923_373024_+\|plate	type VI secretion system baseplate subunit TssG	NA	NA	NA	NA

DBSCAN-SWA_3

1223098 : 1278229

Paenibacillus_phage(28.57%)

transposase,integrase

attL 1215847:1215863|attR 1234480:1234496

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
1215847:1215863	attL	NA	NA	NA	NA
WP_012492455.1\|1223098_1224301_+\|integrase	integrase arm-type DNA-binding domain-containing protein	B7SYF8	Stenotrophomonas_phage	1.3e-108	50.8
WP_006481795.1\|1224367_1225225_+	hypothetical protein	NA	NA	NA	NA
WP_006481798.1\|1225498_1225702_+	hypothetical protein	NA	NA	NA	NA
WP_012492456.1\|1225705_1226032_+	hypothetical protein	NA	NA	NA	NA
WP_006481815.1\|1226077_1227535_+	DUF3987 domain-containing protein	NA	NA	NA	NA
WP_012492458.1\|1228248_1229448_+	inovirus-type Gp2 protein	NA	NA	NA	NA
WP_085964347.1\|1230089_1230907_-\|transposase	IS5-like element IS402 family transposase	A0A0N9SHJ4	Paenibacillus_phage	1.1e-07	35.0
WP_006481789.1\|1231980_1232850_-	ImmA/IrrE family metallo-endopeptidase	NA	NA	NA	NA
WP_006481786.1\|1232842_1233166_-	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_006481809.1\|1233333_1233498_+	hypothetical protein	NA	NA	NA	NA
WP_012492461.1\|1233592_1234837_+	nucleotidyltransferase	NA	NA	NA	NA
1234480:1234496	attR	NA	NA	NA	NA
WP_012492462.1\|1234837_1235308_+	hypothetical protein	NA	NA	NA	NA
WP_085964347.1\|1235667_1236485_-\|transposase	IS5-like element IS402 family transposase	A0A0N9SHJ4	Paenibacillus_phage	1.1e-07	35.0
WP_006492364.1\|1237518_1238112_-	CGNR zinc finger domain-containing protein	NA	NA	NA	NA
WP_006481826.1\|1238250_1239141_-	alpha/beta hydrolase	NA	NA	NA	NA
WP_158305052.1\|1239201_1239915_-	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_085964349.1\|1240205_1241334_+\|transposase	IS3-like element ISBcen15 family transposase	S5WIU1	Leptospira_phage	6.2e-49	43.4
WP_006481836.1\|1242602_1243580_+	DUF4105 domain-containing protein	NA	NA	NA	NA
WP_006481833.1\|1243657_1245031_+	hypothetical protein	NA	NA	NA	NA
WP_006481739.1\|1245110_1246451_-	AraC family transcriptional regulator	NA	NA	NA	NA
WP_006481741.1\|1246927_1248049_+	glycosyltransferase family 4 protein	NA	NA	NA	NA
WP_006481834.1\|1248045_1248807_+	polysaccharide deacetylase family protein	NA	NA	NA	NA
WP_006481742.1\|1248803_1250606_+	hypothetical protein	NA	NA	NA	NA
WP_006481779.1\|1251003_1252008_+	AraC family transcriptional regulator	NA	NA	NA	NA
WP_006481806.1\|1252016_1252754_-	SDR family oxidoreductase	NA	NA	NA	NA
WP_006481747.1\|1252796_1253699_-	transporter	NA	NA	NA	NA
WP_006481775.1\|1253722_1255252_-	aldehyde dehydrogenase	NA	NA	NA	NA
WP_006481808.1\|1255533_1256628_-	porin	NA	NA	NA	NA
WP_043033214.1\|1256838_1257540_-	Asp/Glu racemase	NA	NA	NA	NA
WP_006481780.1\|1257622_1258993_-	MFS transporter	NA	NA	NA	NA
WP_006481824.1\|1259004_1260144_-	FAD-dependent monooxygenase	NA	NA	NA	NA
WP_006481807.1\|1260155_1260638_-	thioesterase family protein	NA	NA	NA	NA
WP_006481832.1\|1260634_1262302_-	AMP-binding protein	NA	NA	NA	NA
WP_006481769.1\|1262323_1263205_-	VOC family protein	NA	NA	NA	NA
WP_006492256.1\|1263268_1264552_-	hypothetical protein	NA	NA	NA	NA
WP_006481792.1\|1264681_1265407_-	TetR family transcriptional regulator	NA	NA	NA	NA
WP_077176183.1\|1267179_1267554_+	IS66 family insertion sequence hypothetical protein	NA	NA	NA	NA
WP_006481817.1\|1267550_1267889_+	IS66 family insertion sequence element accessory protein TnpB	NA	NA	NA	NA
WP_006484960.1\|1267952_1269506_+\|transposase	IS66-like element ISBcen19 family transposase	A0A218MNE7	uncultured_virus	3.3e-125	46.4
WP_012492468.1\|1270535_1273043_+	type VI secretion system tip protein VgrG	A0A2H4JCD4	uncultured_Caudovirales_phage	3.7e-33	26.3
WP_006481774.1\|1273103_1275986_+	SH3 domain-containing protein	NA	NA	NA	NA
WP_012492469.1\|1275995_1276532_+	hypothetical protein	NA	NA	NA	NA
WP_012492470.1\|1276544_1276796_+	PAAR domain-containing protein	NA	NA	NA	NA
WP_041494516.1\|1276864_1277098_+	hypothetical protein	NA	NA	NA	NA
WP_102896096.1\|1277108_1278229_-\|transposase	IS3 family transposase	S5WIU1	Leptospira_phage	2.1e-49	39.9

DBSCAN-SWA_4

1377323 : 1426774

Bacillus_phage(21.43%)

transposase,plate,protease

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_006490511.1\|1377323_1379222_+\|protease	ATP-dependent zinc metalloprotease FtsH	M4QMW8	Micromonas_pusilla_virus	1.9e-111	41.0
WP_006493125.1\|1379250_1380192_+	dihydropteroate synthase	A0A0B5J4J5	Pandoravirus	8.3e-23	33.0
WP_006490564.1\|1380219_1381575_+	phosphoglucosamine mutase	NA	NA	NA	NA
WP_006490565.1\|1382014_1383049_+	phosphate ABC transporter substrate-binding protein PstS	A0A1D7SRJ6	Cyanophage	1.5e-44	35.6
WP_006490596.1\|1383143_1384130_+	phosphate ABC transporter permease PstC	NA	NA	NA	NA
WP_034178403.1\|1384126_1385020_+	phosphate ABC transporter permease PstA	NA	NA	NA	NA
WP_006490515.1\|1385035_1385884_+	phosphate ABC transporter ATP-binding protein PstB	W8CYL7	Bacillus_phage	9.5e-18	33.5
WP_006490618.1\|1385902_1386607_+	phosphate signaling complex protein PhoU	NA	NA	NA	NA
WP_006750313.1\|1386638_1387340_+	phosphate regulon transcriptional regulator PhoB	W8CYM9	Bacillus_phage	1.7e-33	37.3
WP_006490622.1\|1387397_1388717_+	phosphate regulon sensor histidine kinase PhoR	W8CYF6	Bacillus_phage	4.6e-35	36.0
WP_006490552.1\|1388804_1390868_-	polyphosphate kinase 1	NA	NA	NA	NA
WP_006490522.1\|1391147_1392662_+	exopolyphosphatase	NA	NA	NA	NA
WP_012492497.1\|1392768_1393209_-	hypothetical protein	NA	NA	NA	NA
WP_006490592.1\|1393669_1394131_+	phosphohistidine phosphatase SixA	NA	NA	NA	NA
WP_006490555.1\|1394302_1395109_+	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_006476323.1\|1395316_1395487_-	hypothetical protein	NA	NA	NA	NA
WP_006490588.1\|1395622_1395805_+	hypothetical protein	NA	NA	NA	NA
WP_006490551.1\|1395824_1397204_-	MATE family efflux transporter	NA	NA	NA	NA
WP_006493122.1\|1397214_1397538_-	DUF2288 domain-containing protein	NA	NA	NA	NA
WP_006490583.1\|1397610_1399230_-	AMP-binding protein	A0A2H4PQU7	Staphylococcus_phage	1.0e-60	33.8
WP_006490610.1\|1399598_1400291_-	peptidoglycan DD-metalloendopeptidase family protein	A0A1W6JQH9	Corynebacterium_phage	6.2e-07	38.1
WP_006490569.1\|1400423_1401335_-	aldose 1-epimerase	NA	NA	NA	NA
WP_006490581.1\|1401814_1402645_+	undecaprenyl-diphosphate phosphatase	NA	NA	NA	NA
WP_012492498.1\|1403501_1403879_+	DUF3592 domain-containing protein	NA	NA	NA	NA
WP_012492499.1\|1403903_1404476_+	hypothetical protein	NA	NA	NA	NA
WP_006490600.1\|1404477_1406355_-\|plate	type VI secretion system baseplate subunit TssF	NA	NA	NA	NA
WP_006490582.1\|1406494_1408606_+	type VI secretion system tip protein VgrG	A0A077K8Q4	Ralstonia_phage	2.0e-64	31.1
WP_012492501.1\|1408617_1409910_+	DUF2169 domain-containing protein	NA	NA	NA	NA
WP_020979811.1\|1409894_1411085_+	DUF4150 domain-containing protein	NA	NA	NA	NA
WP_006490573.1\|1411195_1411993_+	ankyrin repeat domain-containing protein	NA	NA	NA	NA
WP_085964368.1\|1412497_1413058_+	HNH/ENDO VII family nuclease	NA	NA	NA	NA
WP_124714746.1\|1413071_1413506_+	hypothetical protein	NA	NA	NA	NA
WP_012492505.1\|1413508_1413943_+	hypothetical protein	NA	NA	NA	NA
WP_006490534.1\|1414665_1416678_+	anti-phage defense ZorAB system ZorA	NA	NA	NA	NA
WP_102896096.1\|1417104_1418225_-\|transposase	IS3 family transposase	S5WIU1	Leptospira_phage	2.1e-49	39.9
WP_006490615.1\|1418643_1420284_+	hypothetical protein	NA	NA	NA	NA
WP_006482411.1\|1420373_1421147_-	AAA family ATPase	A0A2L1IVB6	Escherichia_phage	4.2e-81	56.9
WP_006482449.1\|1421143_1422172_-\|transposase	IS21-like element ISBcen13 family transposase	A0A2L1IVA1	Escherichia_phage	2.1e-72	44.1
WP_085964349.1\|1423780_1424910_-\|transposase	IS3-like element ISBcen15 family transposase	S5WIU1	Leptospira_phage	6.2e-49	43.4
WP_102896096.1\|1425653_1426774_-\|transposase	IS3 family transposase	S5WIU1	Leptospira_phage	2.1e-49	39.9

DBSCAN-SWA_5

1683684 : 1766346

Burkholderia_phage(92.31%)

capsid,holin,tail,plate,transposase,terminase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_127837586.1\|1683684_1684125_+\|transposase	transposase	NA	NA	NA	NA
WP_006483501.1\|1684226_1684688_-	DUF2147 domain-containing protein	NA	NA	NA	NA
WP_006483487.1\|1684862_1686548_-	ShlB/FhaC/HecB family hemolysin secretion/activation protein	NA	NA	NA	NA
WP_012492564.1\|1686692_1688117_-	collagen-like triple helix repeat-containing protein	NA	NA	NA	NA
WP_012492565.1\|1688157_1689831_-	collagen-like triple helix repeat-containing protein	NA	NA	NA	NA
WP_006483497.1\|1690508_1690679_+	Flp family type IVb pilin	NA	NA	NA	NA
WP_006483488.1\|1690766_1691261_+	prepilin peptidase	NA	NA	NA	NA
WP_006483477.1\|1691257_1691752_+	pilus assembly protein	NA	NA	NA	NA
WP_006483496.1\|1691846_1692752_+	Flp pilus assembly protein CpaB	NA	NA	NA	NA
WP_006483494.1\|1692774_1694106_+	type II and III secretion system protein family protein	NA	NA	NA	NA
WP_006483491.1\|1694181_1695420_+	fimbrial protein	NA	NA	NA	NA
WP_006483500.1\|1695423_1696776_+	CpaF family protein	NA	NA	NA	NA
WP_012492566.1\|1696768_1697749_+	type II secretion system F family protein	NA	NA	NA	NA
WP_006483478.1\|1697753_1698752_+	type II secretion system F family protein	NA	NA	NA	NA
WP_006483480.1\|1698781_1699609_+	hypothetical protein	NA	NA	NA	NA
WP_006483481.1\|1699632_1699962_+	DUF3613 domain-containing protein	NA	NA	NA	NA
WP_006483498.1\|1699974_1701786_+	hypothetical protein	NA	NA	NA	NA
WP_006483492.1\|1701799_1703191_+	sigma-54-dependent Fis family transcriptional regulator	NA	NA	NA	NA
WP_034178628.1\|1703245_1703953_+	DUF2968 domain-containing protein	NA	NA	NA	NA
WP_012492570.1\|1704034_1704601_-	RNA chaperone Hfq	NA	NA	NA	NA
WP_012492571.1\|1704896_1705181_+	hypothetical protein	NA	NA	NA	NA
WP_006485282.1\|1705208_1706126_-	DUF1571 domain-containing protein	NA	NA	NA	NA
WP_006485283.1\|1706155_1707910_-	AMP-binding protein	A0A2H4PQM9	Staphylococcus_phage	1.8e-39	25.9
WP_006485289.1\|1708067_1708889_-	TetR family transcriptional regulator	NA	NA	NA	NA
WP_006495319.1\|1709104_1710325_-	MFS transporter	NA	NA	NA	NA
WP_006485286.1\|1710606_1711149_+	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_006485279.1\|1711274_1711901_+	chromosome partitioning protein ParB	NA	NA	NA	NA
WP_006485288.1\|1711926_1713657_+	SulP family inorganic anion transporter	NA	NA	NA	NA
WP_006485285.1\|1713690_1714626_-	carbohydrate kinase	NA	NA	NA	NA
WP_006485275.1\|1714760_1715705_-	ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_006485281.1\|1715805_1716843_-	ribose ABC transporter permease	NA	NA	NA	NA
WP_006485287.1\|1716885_1718439_-	sugar ABC transporter ATP-binding protein	A0A2H4PQG7	Staphylococcus_phage	1.2e-13	27.5
WP_006491498.1\|1718425_1719673_-	ROK family protein	NA	NA	NA	NA
WP_006484154.1\|1720496_1721486_-	aliphatic sulfonate ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_006484152.1\|1722009_1724484_+	ribonuclease R	Q0GXV6	Lactococcus_phage	1.1e-69	33.5
WP_006484150.1\|1724632_1725376_+	23S rRNA (guanosine(2251)-2'-O)-methyltransferase RlmB	NA	NA	NA	NA
WP_006484228.1\|1725485_1726358_+	N-acetylmuramoyl-L-alanine amidase	A0A076YN96	Rhizobium_phage	1.3e-09	29.7
WP_006484224.1\|1726450_1727146_+	ribose-5-phosphate isomerase RpiA	NA	NA	NA	NA
WP_006484155.1\|1727428_1728145_+	FadR family transcriptional regulator	NA	NA	NA	NA
WP_006484160.1\|1729076_1729787_-	hypothetical protein	B5TAB3	Burkholderia_phage	4.8e-132	100.0
WP_006484129.1\|1729860_1732089_-	hypothetical protein	B5TAB2	Burkholderia_phage	0.0e+00	100.0
WP_006484169.1\|1732096_1733074_-	hypothetical protein	B5TAB1	Burkholderia_phage	1.8e-185	99.7
WP_012492575.1\|1733073_1733673_-	DUF2313 domain-containing protein	B5TAB0	Burkholderia_phage	9.7e-110	100.0
WP_006484194.1\|1733675_1734797_-\|plate	baseplate J/gp47 family protein	B5TAA9	Burkholderia_phage	5.2e-205	100.0
WP_006484137.1\|1734793_1735375_-	phage GP46 family protein	B5TAA8	Burkholderia_phage	1.9e-110	100.0
WP_006484159.1\|1735459_1735981_-\|plate	phage baseplate assembly protein	B5TAA7	Burkholderia_phage	5.0e-94	100.0
WP_006484189.1\|1735980_1737138_-	hypothetical protein	B5TAA6	Burkholderia_phage	6.7e-224	100.0
WP_012492576.1\|1737143_1738514_-	DNA circularization N-terminal domain-containing protein	B5TAA5	Burkholderia_phage	3.2e-257	99.8
WP_006484120.1\|1738513_1740949_-\|tail	phage tail tape measure protein	B5TAA4	Burkholderia_phage	0.0e+00	100.0
WP_006484197.1\|1740997_1741552_-\|tail	phage tail assembly protein	B5TAA3	Burkholderia_phage	8.2e-95	100.0
WP_012492578.1\|1741634_1742006_-	hypothetical protein	B5TAA2	Burkholderia_phage	3.1e-66	100.0
WP_006484128.1\|1742051_1743530_-\|tail	tail sheath protein	B5TAA1	Burkholderia_phage	4.6e-270	100.0
WP_006484122.1\|1743573_1743852_-	hypothetical protein	B5TAA0	Burkholderia_phage	4.3e-44	100.0
WP_006484182.1\|1743835_1744438_-	DUF1834 family protein	B5TA99	Burkholderia_phage	3.6e-112	100.0
WP_012492580.1\|1744437_1744869_-	phage virion morphogenesis protein	B5TA98	Burkholderia_phage	1.3e-76	100.0
WP_006484126.1\|1744865_1745369_-	DUF1320 family protein	B5TA97	Burkholderia_phage	2.4e-93	100.0
WP_006484139.1\|1745365_1745755_-	hypothetical protein	B5TA96	Burkholderia_phage	4.6e-28	100.0
WP_006484206.1\|1745829_1746777_-	hypothetical protein	B5TA95	Burkholderia_phage	2.5e-176	100.0
WP_006484162.1\|1746827_1747184_-	DUF2190 family protein	B5TA94	Burkholderia_phage	2.0e-54	100.0
WP_006484117.1\|1747229_1748375_-	hypothetical protein	B5TA92	Burkholderia_phage	1.0e-216	100.0
WP_006484119.1\|1748588_1748987_-	hypothetical protein	B5TA91	Burkholderia_phage	1.1e-69	100.0
WP_006484158.1\|1748983_1749424_-	regulatory protein GemA	B5TA90	Burkholderia_phage	2.6e-75	100.0
WP_006484225.1\|1749425_1749746_-	hypothetical protein	B5TA89	Burkholderia_phage	5.3e-54	100.0
WP_006484220.1\|1749745_1749913_-	hypothetical protein	NA	NA	NA	NA
WP_006484140.1\|1749909_1750743_-	hypothetical protein	B5TA88	Burkholderia_phage	9.3e-159	100.0
WP_006484135.1\|1750819_1751092_-	HU family DNA-binding protein	B5TA87	Burkholderia_phage	3.1e-39	100.0
WP_006484203.1\|1751154_1751547_-	hypothetical protein	B5TA86	Burkholderia_phage	2.4e-72	100.0
WP_006484130.1\|1751557_1752184_-	DUF3164 family protein	B5TA85	Burkholderia_phage	8.3e-112	100.0
WP_006484204.1\|1752180_1752768_-	hypothetical protein	B5TA84	Burkholderia_phage	7.6e-91	100.0
WP_006484217.1\|1752754_1753060_-	hypothetical protein	B5TA83	Burkholderia_phage	1.3e-46	100.0
WP_006484199.1\|1753056_1753245_-	hypothetical protein	B5TA82	Burkholderia_phage	7.2e-27	100.0
WP_006484208.1\|1753252_1754245_-	AAA family ATPase	B5TA81	Burkholderia_phage	5.3e-185	100.0
WP_012492581.1\|1754254_1755880_-\|transposase	Mu transposase C-terminal domain-containing protein	B5TA80	Burkholderia_phage	0.0e+00	100.0
WP_012492582.1\|1755919_1756972_-	hypothetical protein	B5TA79	Burkholderia_phage	8.9e-191	100.0
WP_006484183.1\|1756968_1757160_-	DNA-binding protein	B5TA78	Burkholderia_phage	3.5e-29	100.0
WP_012492584.1\|1757241_1757712_+	helix-turn-helix transcriptional regulator	B5TA77	Burkholderia_phage	2.6e-78	100.0
WP_006484125.1\|1757766_1758300_+	hypothetical protein	B5TA76	Burkholderia_phage	1.9e-93	100.0
WP_012492585.1\|1758292_1758901_+	hypothetical protein	B5TA75	Burkholderia_phage	7.6e-110	100.0
WP_006491508.1\|1759042_1759417_+\|holin	putative holin	B5TA74	Burkholderia_phage	8.0e-62	98.4
WP_006484177.1\|1759413_1760085_+	lytic transglycosylase domain-containing protein	B5TA73	Burkholderia_phage	1.4e-112	100.0
WP_006484148.1\|1760081_1760543_+	hypothetical protein	NA	NA	NA	NA
WP_006484200.1\|1760514_1760658_+	hypothetical protein	B5TA72	Burkholderia_phage	4.5e-21	100.0
WP_012492586.1\|1760647_1760872_+	TraR/DksA C4-type zinc finger protein	B5TA71	Burkholderia_phage	4.5e-36	100.0
WP_006484156.1\|1760868_1761159_+	hypothetical protein	B5TA70	Burkholderia_phage	2.8e-46	100.0
WP_006484211.1\|1761162_1761660_+	DUF1804 family protein	B5TA69	Burkholderia_phage	9.6e-87	100.0
WP_006484219.1\|1761666_1763283_+\|terminase	phage terminase large subunit	B5TA68	Burkholderia_phage	0.0e+00	100.0
WP_012492587.1\|1763272_1764808_+	DUF935 family protein	B5TA67	Burkholderia_phage	6.3e-278	99.8
WP_006484136.1\|1764852_1765113_+	hypothetical protein	B5TA66	Burkholderia_phage	5.1e-39	100.0
WP_006484205.1\|1765113_1766346_+\|capsid	minor capsid protein	B5TA65	Burkholderia_phage	4.4e-242	100.0

DBSCAN-SWA_6

2730638 : 2770761

Escherichia_phage(28.57%)

transposase,plate,protease

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_006487668.1\|2730638_2731139_-\|protease	serine protease inhibitor ecotin	NA	NA	NA	NA
WP_006478153.1\|2731282_2731609_+	hypothetical protein	NA	NA	NA	NA
WP_006487627.1\|2731807_2732212_-	hypothetical protein	NA	NA	NA	NA
WP_006487642.1\|2732329_2732710_+	DUF5594 family protein	NA	NA	NA	NA
WP_006487638.1\|2732895_2734263_+	MFS transporter	NA	NA	NA	NA
WP_006487659.1\|2734293_2734887_-	AAA family ATPase	A0A219VHB7	Ochrobactrum_phage	3.0e-26	64.0
WP_006487666.1\|2734879_2736304_-	alpha,alpha-trehalose-phosphate synthase (UDP-forming)	NA	NA	NA	NA
WP_006487640.1\|2736442_2736652_-	hypothetical protein	NA	NA	NA	NA
WP_006487661.1\|2736940_2737492_+	hypothetical protein	NA	NA	NA	NA
WP_006497148.1\|2737488_2737983_+	hypothetical protein	NA	NA	NA	NA
WP_052288951.1\|2738516_2738951_-	hypothetical protein	NA	NA	NA	NA
WP_012492761.1\|2739023_2739275_-	PAAR domain-containing protein	NA	NA	NA	NA
WP_077181119.1\|2739303_2739786_-	hypothetical protein	NA	NA	NA	NA
WP_006482449.1\|2741642_2742671_+\|transposase	IS21-like element ISBcen13 family transposase	A0A2L1IVA1	Escherichia_phage	2.1e-72	44.1
WP_006482411.1\|2742667_2743441_+	AAA family ATPase	A0A2L1IVB6	Escherichia_phage	4.2e-81	56.9
WP_085964347.1\|2745006_2745823_+\|transposase	IS5-like element IS402 family transposase	A0A0N9SHJ4	Paenibacillus_phage	1.1e-07	35.0
WP_012492764.1\|2745967_2746234_+	XapX domain-containing protein	NA	NA	NA	NA
WP_012492765.1\|2746483_2747656_-	porin	NA	NA	NA	NA
WP_012492766.1\|2747652_2749836_-	FUSC family protein	NA	NA	NA	NA
WP_006481910.1\|2749852_2750452_-	LUD domain-containing protein	NA	NA	NA	NA
WP_006481909.1\|2750448_2751822_-	lactate utilization protein	NA	NA	NA	NA
WP_006481907.1\|2751818_2752562_-	(Fe-S)-binding protein	NA	NA	NA	NA
WP_012492768.1\|2752618_2754367_-	D-lactate dehydrogenase	NA	NA	NA	NA
WP_006481906.1\|2754736_2755648_-	LysR family transcriptional regulator	NA	NA	NA	NA
WP_012492769.1\|2755951_2756815_-	NAD(P)-dependent oxidoreductase	NA	NA	NA	NA
WP_006491232.1\|2757926_2758262_+	PepSY domain-containing protein	NA	NA	NA	NA
WP_012492770.1\|2758318_2758915_+	undecaprenyl-diphosphatase	NA	NA	NA	NA
WP_006486529.1\|2758984_2759767_+	membrane protein	NA	NA	NA	NA
WP_012492771.1\|2759795_2760248_+	hypothetical protein	NA	NA	NA	NA
WP_006486551.1\|2760264_2761023_+	membrane protein	NA	NA	NA	NA
WP_085964354.1\|2761105_2761914_-\|transposase	IS5 family transposase	A0A0N9SHJ4	Paenibacillus_phage	6.7e-05	34.3
WP_006482764.1\|2761903_2763163_-\|transposase	IS256-like element IS1356 family transposase	A0A218MNI5	uncultured_virus	1.1e-43	44.4
WP_065814644.1\|2763338_2764565_-	ATP-binding protein	A0A2H4J2R8	uncultured_Caudovirales_phage	1.7e-100	49.0
WP_012492773.1\|2765320_2765806_-	hypothetical protein	NA	NA	NA	NA
WP_006486496.1\|2765809_2767567_-	DUF4150 domain-containing protein	NA	NA	NA	NA
WP_006486541.1\|2767559_2768903_-	DUF2169 domain-containing protein	NA	NA	NA	NA
WP_171984383.1\|2770116_2770761_+\|plate	type VI secretion system baseplate subunit TssF	NA	NA	NA	NA

DBSCAN-SWA_7

2800483 : 2859770

Leptospira_phage(28.57%)

transposase,integrase

attL 2811583:2811599|attR 2864631:2864647

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_102896096.1\|2800483_2801603_+\|transposase	IS3 family transposase	S5WIU1	Leptospira_phage	2.1e-49	39.9
WP_006486497.1\|2802192_2802981_-	alpha/beta hydrolase	NA	NA	NA	NA
WP_006489014.1\|2803110_2804037_+	LysR family transcriptional regulator	NA	NA	NA	NA
WP_006489025.1\|2804178_2804754_-	TetR/AcrR family transcriptional regulator	NA	NA	NA	NA
WP_085964374.1\|2804839_2805484_-	glutathione S-transferase	NA	NA	NA	NA
WP_006489030.1\|2806054_2806948_-	LysR family transcriptional regulator	NA	NA	NA	NA
WP_012492794.1\|2807051_2807930_+	alpha/beta hydrolase	NA	NA	NA	NA
WP_006489039.1\|2807948_2809367_+	3-isopropylmalate dehydratase large subunit	NA	NA	NA	NA
WP_006489026.1\|2809363_2809999_+	3-isopropylmalate dehydratase small subunit	NA	NA	NA	NA
WP_012492795.1\|2810151_2810769_+	TetR/AcrR family transcriptional regulator	NA	NA	NA	NA
WP_012492796.1\|2810916_2812143_+	MFS transporter	NA	NA	NA	NA
2811583:2811599	attL	NA	NA	NA	NA
WP_006489029.1\|2812166_2812373_+	hypothetical protein	NA	NA	NA	NA
WP_012492797.1\|2812877_2813315_+	TIGR03757 family integrating conjugative element protein	NA	NA	NA	NA
WP_006488999.1\|2814226_2815624_+	integrating conjugative element protein	NA	NA	NA	NA
WP_012492798.1\|2815620_2815971_+	hypothetical protein	NA	NA	NA	NA
WP_006489021.1\|2815984_2817502_+	conjugal transfer protein TraG	NA	NA	NA	NA
WP_006489024.1\|2817519_2817897_-	DUF3742 family protein	NA	NA	NA	NA
WP_006489018.1\|2817952_2818366_-	putative toxin-antitoxin system toxin component, PIN family	NA	NA	NA	NA
WP_006489017.1\|2818365_2818584_-	AbrB/MazE/SpoVT family DNA-binding domain-containing protein	NA	NA	NA	NA
WP_006489004.1\|2818915_2820712_+	TraI domain-containing protein	NA	NA	NA	NA
WP_006489022.1\|2820776_2821295_-	hypothetical protein	NA	NA	NA	NA
WP_006489015.1\|2821291_2822215_-	NAD(P)/FAD-dependent oxidoreductase	NA	NA	NA	NA
WP_009618094.1\|2822211_2822661_-	Rrf2 family transcriptional regulator	NA	NA	NA	NA
WP_009618091.1\|2822781_2823081_-	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_006489045.1\|2823185_2823809_+	LysR family substrate-binding domain-containing protein	NA	NA	NA	NA
WP_006397350.1\|2824401_2825151_-	ATP-binding protein	K4HZD4	Acidithiobacillus_phage	4.8e-82	60.7
WP_012492800.1\|2825167_2826724_-\|transposase	IS21-like element IS408 family transposase	K4I413	Acidithiobacillus_phage	1.6e-159	54.9
WP_012492801.1\|2827323_2827839_+	hypothetical protein	NA	NA	NA	NA
WP_006489001.1\|2827886_2828669_+	UPF0489 family protein	NA	NA	NA	NA
WP_006405724.1\|2828755_2829544_+	UPF0489 family protein	NA	NA	NA	NA
WP_006405725.1\|2829562_2829964_-	DUF4113 domain-containing protein	NA	NA	NA	NA
WP_034178583.1\|2830401_2830980_+	hypothetical protein	NA	NA	NA	NA
WP_006405727.1\|2831182_2832142_+	AraC family transcriptional regulator	NA	NA	NA	NA
WP_006489008.1\|2832264_2832831_+	carboxymuconolactone decarboxylase family protein	NA	NA	NA	NA
WP_006489046.1\|2832803_2833919_+	acyl-CoA/acyl-ACP dehydrogenase	NA	NA	NA	NA
WP_006489020.1\|2833915_2834710_+	ABC transporter ATP-binding protein	A0A285PWH2	Cedratvirus	3.4e-09	26.9
WP_006488996.1\|2835904_2836732_+	ABC transporter permease	NA	NA	NA	NA
WP_006405733.1\|2837023_2837785_-	DJ-1/PfpI family protein	NA	NA	NA	NA
WP_006405734.1\|2837871_2838675_-	alpha/beta hydrolase	NA	NA	NA	NA
WP_006405735.1\|2838835_2839753_+	LysR family transcriptional regulator	NA	NA	NA	NA
WP_006489005.1\|2842268_2843060_+	MBL fold metallo-hydrolase	NA	NA	NA	NA
WP_012492804.1\|2843803_2844853_+	carbon-nitrogen hydrolase family protein	NA	NA	NA	NA
WP_006489036.1\|2844904_2845858_-	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_012492805.1\|2846086_2846962_+	transporter	NA	NA	NA	NA
WP_006489043.1\|2847119_2848502_+\|transposase	IS1182 family transposase	NA	NA	NA	NA
WP_102896096.1\|2849953_2851073_+\|transposase	IS3 family transposase	S5WIU1	Leptospira_phage	2.1e-49	39.9
WP_006476181.1\|2853120_2854086_+\|transposase	IS110-like element ISBcen8 family transposase	Q75QL1	Wolbachia_phage	1.3e-23	34.2
WP_006482148.1\|2854504_2855974_-	DUF3987 domain-containing protein	A0A0K0N7B1	Gordonia_phage	3.4e-07	23.2
WP_006482143.1\|2856197_2856545_-	hypothetical protein	NA	NA	NA	NA
WP_006482147.1\|2856608_2856821_-	hypothetical protein	NA	NA	NA	NA
WP_012492806.1\|2857436_2858378_-	hypothetical protein	NA	NA	NA	NA
WP_006482144.1\|2858405_2859770_-\|integrase	integrase family protein	NA	NA	NA	NA
2864631:2864647	attR	NA	NA	NA	NA

DBSCAN-SWA_8

3418039 : 3426169

Enterobacteria_phage(33.33%)

transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_085964347.1\|3418039_3418856_+\|transposase	IS5-like element IS402 family transposase	A0A0N9SHJ4	Paenibacillus_phage	1.1e-07	35.0
WP_006485123.1\|3419148_3420414_-	glycosyltransferase	A0A1V0SAH6	Catovirus	6.4e-10	36.0
WP_006485127.1\|3420442_3421585_-	DegT/DnrJ/EryC1/StrS family aminotransferase	NA	NA	NA	NA
WP_012492907.1\|3421646_3422960_-	ABC transporter ATP-binding protein	M1HV27	Acanthocystis_turfacea_Chlorella_virus	6.4e-05	27.9
WP_006485117.1\|3422949_3423756_-	ABC transporter permease	NA	NA	NA	NA
WP_006485121.1\|3423823_3424732_-	dTDP-4-dehydrorhamnose reductase	I7HXC9	Enterobacteria_phage	1.9e-24	33.8
WP_006485116.1\|3424739_3425291_-	dTDP-4-dehydrorhamnose 3,5-epimerase	I7HJC4	Enterobacteria_phage	1.5e-51	54.7
WP_006485115.1\|3425275_3426169_-	glucose-1-phosphate thymidylyltransferase RfbA	A0A291LA53	Escherichia_phage	1.8e-96	59.2

DBSCAN-SWA_9

3571060 : 3580110

unidentified_phage(16.67%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_006484964.1\|3571060_3572611_+	polynucleotide adenylyltransferase PcnB	H7BUW3	unidentified_phage	9.5e-24	31.3
WP_006476832.1\|3572646_3573189_+	2-amino-4-hydroxy-6- hydroxymethyldihydropteridine diphosphokinase	NA	NA	NA	NA
WP_006484932.1\|3573185_3573872_+	deoxynucleoside kinase	A0A0M3UL55	Enterococcus_phage	7.2e-08	26.4
WP_006485002.1\|3573915_3574731_+	3-methyl-2-oxobutanoate hydroxymethyltransferase	A0A0N7HVJ8	Ostreococcus_lucimarinus_virus	1.8e-37	34.2
WP_006484970.1\|3574841_3576764_-	aminodeoxychorismate synthase component I	S4VT78	Pandoravirus	2.4e-56	37.0
WP_006476837.1\|3576767_3577904_-	molecular chaperone DnaJ	A0A1V0SBY2	Catovirus	5.0e-22	26.9
WP_006484920.1\|3578157_3580110_-	molecular chaperone DnaK	A0A1V0SH73	Hokovirus	2.5e-146	50.3

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. NC_011003

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CRISPR-Cas detection and classification

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Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection

2. NC_011001

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CRISPR-Cas detection and classification

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Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection

3. NC_011002

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection

4. NC_011000

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection