CRISPRimmunity

Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NC_003140	Staphylococcus aureus subsp. aureus N315 plasmid pN315, complete sequence	0 crisprs	csa3	0	0	0	0
NC_002745	Staphylococcus aureus subsp. aureus N315, complete genome	12 crisprs	cas3,DEDDh,DinG,csa3,RT,WYL	7	1	5	2

1. NC_002745

CRISPR-Cas detection and classification

Crispr_ID: NC_002745_1

• CRISPR_ID: NC_002745_1
• CRISPR_location: 188427-188511
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NC_002745_1

Consensus_repeat	Method
TTCTACAGGCAATGCAAGTTGGGGTG	CRISPRCasFinder

spacers of NC_002745_1

>1.1|188453|33|NC_002745|CRISPRCasFinder
TGGGCCCCAACAAAGAGAAATTGGATTCCCAAT

CRISPR arrays and Neighbor proteins around NC_002745_1

CRISPR arrays

The CRISPR arrays of NC_002745_1

>merge|NC_002745|1|188427-188511|CRISPRCasFinder
TTCTACAGGCAATGCAAGTTGGGGTGTGGGCCCCAACAAAGAGAAATTGGATTCCCAATTTCTACAGACAATGCAAGTTGGGGTG

>NC_002745|1|1|188427-188511|CRISPRCasFinder
TTCTACAGGCAATGCAAGTTGGGGTG	TGGGCCCCAACAAAGAGAAATTGGATTCCCAAT
TTCTACAGACAATGCAAGTTGGGGTG

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_002745.2|WP_001237004.1|184374_184758_-|YbaN-family-protein	unknown	unknown	gnl|CDD|377291
NC_002745.2|WP_000171919.1|188954_189467_+|DUF4242-domain-containing-protein	unknown	unknown	gnl|CDD|379428
NC_002745.2|WP_000480603.1|184041_184368_-|staphylobilin-forming-heme-oxygenase-IsdI	unknown	unknown	gnl|CDD|183968
NC_002745.2|WP_000290397.1|185184_186672_+|aldehyde-dehydrogenase-family-protein	unknown	unknown	gnl|CDD|143435
NC_002745.2|WP_000197961.1|191530_192292_+|ABC-transporter-permease	unknown	unknown	gnl|CDD|223673
NC_002745.2|WP_000356963.1|188572_188776_-|hypothetical-protein	unknown	unknown	unknown
NC_002745.2|WP_001291020.1|178778_179984_+|glycosyltransferase-family-4-protein	unknown	unknown	gnl|CDD|340825
NC_002745.2|WP_000826862.1|195496_196747_+|MFS-transporter	unknown	unknown	gnl|CDD|340887
NC_002745.2|WP_000605281.1|197193_204369_+|amino-acid-adenylation-domain-containing-protein	unknown	unknown	gnl|CDD|237108
NC_002745.2|WP_000779504.1|181492_182755_+|nucleotide-sugar-dehydrogenase	unknown	unknown	gnl|CDD|223749
NC_002745.2|WP_001092004.1|193552_193912_+|DUF2294-domain-containing-protein	unknown	unknown	gnl|CDD|227896
NC_002745.2|WP_001230679.1|180551_181439_+|capsular-polysaccharide-type-5/8-biosynthesis-epimerase-CapN	unknown	unknown	gnl|CDD|187543
NC_002745.2|WP_000239647.1|177572_178778_+|capsular-polysaccharide-biosynthesis-protein	unknown	unknown	unknown
NC_002745.2|WP_000171645.1|192304_193336_+|acyl-CoA/acyl-ACP-dehydrogenase	unknown	unknown	gnl|CDD|224871
NC_002745.2|WP_000590854.1|189808_190549_+|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl|CDD|224041
NC_002745.2|WP_001013485.1|187318_188278_+|cation-transporter	unknown	unknown	gnl|CDD|224151
NC_002745.2|WP_000825098.1|179994_180552_+|sugar-transferase	unknown	unknown	gnl|CDD|225059
NC_002745.2|WP_000706135.1|194085_195111_+|NAD-dependent-formate-dehydrogenase	unknown	unknown	gnl|CDD|181041
NC_002745.2|WP_000826669.1|190562_191534_+|ABC-transporter-substrate-binding-protein	unknown	unknown	gnl|CDD|270271
NC_002745.2|WP_000723436.1|182831_183977_+|UDP-N-acetylglucosamine-2-epimerase-(non-hydrolyzing)	unknown	unknown	gnl|CDD|223458

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_002745.2|WP_001237004.1|184374_184758_-|YbaN-family-protein	gnl|CDD|377291	pfam04304, DUF454, Protein of unknown function (DUF454). Predicted membrane protein.	5.80598e-41
NC_002745.2|WP_000480603.1|184041_184368_-|staphylobilin-forming-heme-oxygenase-IsdI	gnl|CDD|183968	PRK13313, PRK13313, staphylobilin-forming heme oxygenase IsdI.	1.40112e-64
NC_002745.2|WP_000290397.1|185184_186672_+|aldehyde-dehydrogenase-family-protein	gnl|CDD|143435	cd07117, ALDH_StaphAldA1, Uncharacterized Staphylococcus aureus AldA1 (SACOL0154) aldehyde dehydrogenase-like. Uncharacterized aldehyde dehydrogenase from Staphylococcus aureus (AldA1, locus SACOL0154) and other similar sequences are present in this CD.	0
NC_002745.2|WP_000197961.1|191530_192292_+|ABC-transporter-permease	gnl|CDD|223673	COG0600, TauC, ABC-type nitrate/sulfonate/bicarbonate transport system, permease component [Inorganic ion transport and metabolism].	1.22607e-73
NC_002745.2|WP_000825098.1|179994_180552_+|sugar-transferase	gnl|CDD|225059	COG2148, WcaJ, Sugar transferases involved in lipopolysaccharide synthesis [Cell envelope biogenesis, outer membrane].	3.08096e-87
NC_002745.2|WP_000826862.1|195496_196747_+|MFS-transporter	gnl|CDD|340887	cd17329, MFS_MdtH_MDR_like, Multidrug resistance protein MdtH and similar multidrug resistance (MDR) transporters of the Major Facilitator Superfamily. This family is composed of Escherichia coli MdtH and similar multidrug resistance (MDR) transporters from bacteria and archaea, many of which remain uncharacterized. MDR transporters are drug/H+ antiporters (DHA) that mediate the efflux of a variety of drugs and toxic compounds, and confer resistance to these compounds. MdtH confers resistance to norfloxacin and enoxacin. MdtH-like MDR transporters belong to the Major Facilitator Superfamily (MFS) of membrane transport proteins, which are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	1.61322e-72
NC_002745.2|WP_000605281.1|197193_204369_+|amino-acid-adenylation-domain-containing-protein	gnl|CDD|237108	PRK12467, PRK12467, peptide synthase; Provisional.	0
NC_002745.2|WP_000779504.1|181492_182755_+|nucleotide-sugar-dehydrogenase	gnl|CDD|223749	COG0677, WecC, UDP-N-acetyl-D-mannosaminuronate dehydrogenase [Cell envelope biogenesis, outer membrane].	0
NC_002745.2|WP_001092004.1|193552_193912_+|DUF2294-domain-containing-protein	gnl|CDD|227896	COG5609, COG5609, Uncharacterized conserved protein [Function unknown].	6.06834e-49
NC_002745.2|WP_001230679.1|180551_181439_+|capsular-polysaccharide-type-5/8-biosynthesis-epimerase-CapN	gnl|CDD|187543	cd05232, UDP_G4E_4_SDR_e, UDP-glucose 4 epimerase, subgroup 4, extended (e) SDRs. UDP-glucose 4 epimerase (aka UDP-galactose-4-epimerase), is a homodimeric extended SDR. It catalyzes the NAD-dependent conversion of UDP-galactose to UDP-glucose, the final step in Leloir galactose synthesis. This subgroup is comprised of bacterial proteins, and includes the Staphylococcus aureus capsular polysaccharide Cap5N, which may have a role in the synthesis of UDP-N-acetyl-d-fucosamine. This subgroup has the characteristic active site tetrad and NAD-binding motif of the extended SDRs. Extended SDRs are distinct from classical SDRs. In addition to the Rossmann fold (alpha/beta folding pattern with a central beta-sheet) core region typical of all SDRs, extended SDRs have a less conserved C-terminal extension of approximately 100 amino acids. Extended SDRs are a diverse collection of proteins, and include isomerases, epimerases, oxidoreductases, and lyases; they typically have a TGXXGXXG cofactor binding motif. SDRs are a functionally diverse family of oxidoreductases that have a single domain with a structurally conserved Rossmann fold, an NAD(P)(H)-binding region, and a structurally diverse C-terminal region. Sequence identity between different SDR enzymes is typically in the 15-30% range; they catalyze a wide range of activities including the metabolism of steroids, cofactors, carbohydrates, lipids, aromatic compounds, and amino acids, and act in redox sensing. Classical SDRs have an TGXXX[AG]XG cofactor binding motif and a YXXXK active site motif, with the Tyr residue of the active site motif serving as a critical catalytic residue (Tyr-151, human 15-hydroxyprostaglandin dehydrogenase numbering). In addition to the Tyr and Lys, there is often an upstream Ser and/or an Asn, contributing to the active site; while substrate binding is in the C-terminal region, which determines specificity. The standard reaction mechanism is a 4-pro-S hydride transfer and proton relay involving the conserved Tyr and Lys, a water molecule stabilized by Asn, and nicotinamide. Atypical SDRs generally lack the catalytic residues characteristic of the SDRs, and their glycine-rich NAD(P)-binding motif is often different from the forms normally seen in classical or extended SDRs. Complex (multidomain) SDRs such as ketoreductase domains of fatty acid synthase have a GGXGXXG NAD(P)-binding motif and an altered active site motif (YXXXN). Fungal type ketoacyl reductases have a TGXXXGX(1-2)G NAD(P)-binding motif.	1.93098e-117
NC_002745.2|WP_000171645.1|192304_193336_+|acyl-CoA/acyl-ACP-dehydrogenase	gnl|CDD|224871	COG1960, CaiA, Acyl-CoA dehydrogenases [Lipid metabolism].	2.67474e-20
NC_002745.2|WP_000723436.1|182831_183977_+|UDP-N-acetylglucosamine-2-epimerase-(non-hydrolyzing)	gnl|CDD|223458	COG0381, WecB, UDP-N-acetylglucosamine 2-epimerase [Cell envelope biogenesis, outer membrane].	0
NC_002745.2|WP_001013485.1|187318_188278_+|cation-transporter	gnl|CDD|224151	COG1230, CzcD, Co/Zn/Cd efflux system component [Inorganic ion transport and metabolism].	4.11026e-108
NC_002745.2|WP_000171919.1|188954_189467_+|DUF4242-domain-containing-protein	gnl|CDD|379428	pfam14026, DUF4242, Protein of unknown function (DUF4242). This family of proteins is functionally uncharacterized. This family of proteins is found in bacteria and archaea. Proteins in this family are typically between 90 and 170 amino acids in length. There is a single completely conserved residue C that may be functionally important.	2.56603e-26
NC_002745.2|WP_000706135.1|194085_195111_+|NAD-dependent-formate-dehydrogenase	gnl|CDD|181041	PRK07574, PRK07574, NAD-dependent formate dehydrogenase.	0
NC_002745.2|WP_000826669.1|190562_191534_+|ABC-transporter-substrate-binding-protein	gnl|CDD|270271	cd13553, PBP2_NrtA_CpmA_like, Substrate binding domain of ABC-type nitrate/bicarbonate transporters, a member of the type 2 periplasmic binding fold superfamily. This subfamily includes nitrate (NrtA) and bicarbonate (CmpA) receptors. These domains are found in eubacterial perisplamic-binding proteins that serve as initial receptors in the ABC transport of bicarbonate, nitrate, taurine, or a wide range of aliphatic sulfonates, while other closest homologs are involved in thiamine (vitamin B1) biosynthetic pathway and desulfurization (DszB). After binding their ligand with high affinity, they interact with a cognate membrane transport complex comprised of two integral membrane domains and two cytoplasmically located ATPase domains. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis. These binding proteins belong to the PBP2 superfamily of periplasmic binding proteins that differ in size and ligand specificity, but have similar tertiary structures consisting of two globular subdomains connected by a flexible hinge. They have been shown to bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap.	6.75927e-52
NC_002745.2|WP_001291020.1|178778_179984_+|glycosyltransferase-family-4-protein	gnl|CDD|340825	cd03794, GT4_WbuB-like, Escherichia coli WbuB and similar proteins. This family is most closely related to the GT1 family of glycosyltransferases. WbuB in E. coli is involved in the biosynthesis of the O26 O-antigen. It has been proposed to function as an N-acetyl-L-fucosamine (L-FucNAc) transferase.	3.56278e-74
NC_002745.2|WP_000590854.1|189808_190549_+|ABC-transporter-ATP-binding-protein	gnl|CDD|224041	COG1116, TauB, ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component [Inorganic ion transport and metabolism].	2.18703e-112

Protein sequences

>NC_002745.2|WP_001013485.1|187318_188278_+|cation-transporter
MNGKKANTINRYKYFHHVNHQKIQQSSKKTLWASLIITLLFTVIEFVGGLVSNSLALLSDSFHMLSDVLALGLSMLAIYFASKKPTARYTFGYLRFEILVAFLNGLALIVISIWILYEAIVRIIYPQPIESGIMFMIASIGLLVNIILTIILVRSLKQEDNINIQSALWHFMGDLLNSIGVIVAVVLIYFTGWRIIDPIISIVISLIILRGGYKITRNAWLILMESVPQHLDTDQIMADIKNIDGILDVHEFHLWSITTEHYSLSAHVVLDKKYEGDDYQAIDQVSSLLKEKYGIAHSTLQIENLQLNPLDEPYFDKLT
>NC_002745.2|WP_000290397.1|185184_186672_+|aldehyde-dehydrogenase-family-protein
MAVNVRDYIAENYGLFINGEFVKGSSDETIEVTNPATGETLSHITRAKDKDVDHAVKVAQEAFESWSLTSKSERAQMLRDIGDKLMAQKDKIAMIETLNNGKPIRETTAIDIPFAARHFHYFASVIETEEGTVNDIDKDTMSIVRHEPIGVVGAVVAWNFPMLLAAWKIAPAIAAGNTIVIQPSSSTPLSLLEVAKIFQEVLPKGVVNILTGKGSESGNAIFNHDGVDKLSFTGSTDVGYQVAEAAAKHLVPATLELGGKSANIILDDANLDLAVEGIQLGILFNQGEVCSAGSRLLVHEKIYDQLVPRLQEAFSNIKVGDPQDEATQMGSQTGKDQLDKIQSYIDAAKESDAQILAGGHRLTENGLDKGFFFEPTLIAVPDNHHKLAQEEIFGPVLTVIKVKDDQEAIDIANDSEYGLAGGVFSQNITRALNIAKAVRTGRIWINTYNQVPEGAPFGGYKKSGIGRETYKGALSNYQQVKNIYIDTSNALKGLY
>NC_002745.2|WP_001237004.1|184374_184758_-|YbaN-family-protein
MRLILIVIGLIFTALGIAGAVLPLLPTTPFLLVAVFCFARSSDRFYNWLINQKIYKEYVENFYLHRGYTLQQKIKILISLYIVIGFSIYMVDVLAVRVGLIIMVIIQTAVLFTFVKTLPKSNHKIEE
>NC_002745.2|WP_000480603.1|184041_184368_-|staphylobilin-forming-heme-oxygenase-IsdI
MFMAENRLQLQKGSAEETIERFYNRQGIETIEGFQQMFVTKTLNTEDTDEVKILTIWESEDSFNNWLNSDVFKEAHKNVRLKSDDDGQQSPILSNKVFKYDIGYHYQK
>NC_002745.2|WP_000723436.1|182831_183977_+|UDP-N-acetylglucosamine-2-epimerase-(non-hydrolyzing)
MKKIMVIFGTRPEAIKMAPLVKEIDHNGNFEANIVITAQHRDMLDSVLSIFDIQADHDLNIMQDQQTLADLTANALAKLDSIINEEQPDMILVHGDTTTTFVGSLAAFYHQIPVGHVEAGLRTHQKYSPFPEELNRVMVSNIAELNFAPTVIAAKNLLFENKDKERIFITGNTVIDALSTTVQNDFVSTIINKHKGKKVILLTAHRRENIGEPMHQIFKAVRDLADEYKDVVFIYPMHRNPKVRAIAEKYLSGRNRIELIEPLDAIEFHNFTNQSYLVLTDSGGIQEEAPTFGKPVLVLRNHTERPEGVEAGTSRVIGTDYDNIVRNVKQLIEDDEAYQRMSQANNPYGDGQASRRICEAIEYYFGLRSDKPDEFVPLRHK
>NC_002745.2|WP_000779504.1|181492_182755_+|nucleotide-sugar-dehydrogenase
MKLTVVGLGYIGLPTSIMFAKHGVDVLGVDINQQTIDKLQSGQISIEEPGLQEVYEEVLSSGKLKVSTTPEASDVFIIAVPTPNNDDQYRSCDISLVMRALDSILPFLEKGNTIIVESTIAPKTMDDFVKPVIENLGFTIGEDICLVHCPERVLPGKILEELVHNNRIIGGVTKACIEAGKYVYRTFVQGEMIETDARTAEMSKLMENTYRDVNIALANELTKICNNLNINVLDVIEMANKHPRVNIHQPGPGVGGHCLAVDPYFIIAKDPENAKLIQTGREINNSMPAYVVDTTKQIIKALSGNKVTVFGLTYKGDVDDIRESPAFDIYELLNQEPDIEVCAYDPHVELDFVEHDMSHAVKDASLVLILSDHSEFKNLSDSHFDKMKHKVIFDTKNVVKSSFEDVSYYNYGNIFNFIDK
>NC_002745.2|WP_001230679.1|180551_181439_+|capsular-polysaccharide-type-5/8-biosynthesis-epimerase-CapN
MRKNILITGVHGYIGNALKDKLIEQGHQVDQINVRNQLWKSTSFKDYDVLIHTAALVHNNSPQARLSDYMQVNMLLTKQLAQKAKAEDVKQFIFMSTMAVYGKEGQVGKSDQIDTQTPMNPTTNYGISKKFAEQALQELISDSFKVAIVRPPMIYGAHCPGNFQRLMQLSKRLPIIPNINNQRSALYIKHLTAFIDQLISLEVTGVYHPQDSFYFDTSSVMYEIRRQSHRKTVLINMPSVLNKYFNKLSVFRKLFGNLTYSNTLYENNNALEVIPGKMSLVIADIMDETTTKDKA
>NC_002745.2|WP_000825098.1|179994_180552_+|sugar-transferase
MKRLFDVVSSIYGLVVLSPILLITALLIKMESPGPAIFKQKRPTINNELFNIYKFRSMKIDTPNVATDLMDSTSYITKTGKVIRKTSIDELPQLLNVLKGEMSIVGPRPALYNQYELIEKRTKANVHTIRPGVTGLAQVMGRDDITDDQKVAYDHYYLTHQSMMLDMYIIYKTIKNIVTSEGVHH
>NC_002745.2|WP_001291020.1|178778_179984_+|glycosyltransferase-family-4-protein
MSEKKILILCQYFYPEYVSSATLPTQLAEDLIANHINVDVMCGWPYEYSNHKQVSKTEMHRGIRIRRLKYSRFNNKSKVGRIINFFSLFSKFVINIPKMLKYDQILVYSNPPILPLIPDVLHRLLKKKYSFVVYDIAPDNAIKTGATRPGSMIDKLMRYINRHVYKNAENVIVLGTEMKNYLLNHQISKNADNIHVIPNWYDMRQLQDNRIYNDTFKAYREQYDKILLYSGNMGQLQDMETLISFLKLNKDQPQTLTILCGHGKKFADVKTAIEDHRIENVKMFEFLTGTDYADVLKIADVCIASLIKEGVGLGVPSKNYGYLAAKKPLVLIMDKQSDIVQHVEQYDAGIQIDNGDAHAIYNFINTHSSKELHEMGERAHQLFKDKYTREINTMKYYNLLK
>NC_002745.2|WP_000239647.1|177572_178778_+|capsular-polysaccharide-biosynthesis-protein
MVKKVFIMDSVKTIIGTLLIALGLQFLAYPIINQRVGNEAFGSILTIYTIITITSVVLGNTLNNIRLINMNLYKSNHYYWKFVSILLISILIESIALIIVFLYFFNLNTIDIIFLILLNILMCLRIYLNVFFRMTLKYNQILYIALIQFLGLLIGLFLYYLIQNWIVCFITSELFATIYTLVKLRGLTIGEYQSEDNNVVKDYVMLLSTNSLNNLNLYLDRLILLPIIGGTAVTISFLSTFIGKMLATFLYPINNVVLSYISVNESDNIKKQYLKTNLFAIAALCLVMIICYPITLIIVSLLYNIDSSLYSKFIILGNIGVLFNAVSIMIQTLNTKHASITLQANYMTLHTITFIFITILMTIAFGLNGFFWTTLFSNIIKYVILNIIGLKSKFINKKDVD
>NC_002745.2|WP_000356963.1|188572_188776_-|hypothetical-protein
MDKESVVASLARNKKIAVETMAGQRYIIERILHTNDEKHIHILKPKDVVLDVDSIKEIDENHLNDAT
>NC_002745.2|WP_000171919.1|188954_189467_+|DUF4242-domain-containing-protein
MTLFLLEANNLDFASTKEELEAKAASLSTKTIPTLIEVQATENLTHGYFIVEANDEAEAKQFLTEADISIQLVKEVRLVGKDLDEVKNGDAHVDYLVTWNIPEGITMDQYLARKKKNSVHYEEVPEVEFKRTYVCEDMSKCICLYNAPDEEAVRRARKAVDTPIDGIEKL
>NC_002745.2|WP_000590854.1|189808_190549_+|ABC-transporter-ATP-binding-protein
MIKIQQLQHHFGSHKVIHNFNLDISKGEIVTFIGKSGCGKSTLLNVIGGFIHPSSGRVIIDNEIKQQPSPDCLMLFQHHNLLPWKTINDNIRIGFQQKISDEEINAQLKLVDLEDRGKHFPEQLSGGMKQRVALCRAHVHKPNVILMDEPLGALDAFTRYKLQDQLVQLKHKTQSTIILVTHDIDEAIYLSDRIVLLGEGCNIISQYEITASHPRSRNDSHLLKIRNEIMETFALNHHQVEPEYYL
>NC_002745.2|WP_000826669.1|190562_191534_+|ABC-transporter-substrate-binding-protein
MKRLSIIVIIGIFIITGCDWQRTSKEPSKNAQNQQVIKIGYLPITHSANLMMTKKLLSQYNHPKYKLELVKFNNWPDLMDALNSGRIDGASTLIELAMKSKQKGSNIKAVALGHHEGNVIMGQKGMHLNEFNNGDDYHFGIPHRYSTHYLLLEELRKQLKIKPGHFSYHEMSPAEMPAALSEHRITGYSVAEPFGALGEKLGKGKTLKHGDDVIPDAYCCVLVLRGELLDQHKDVAQAFVQDYKKSGFKMNDRKQSVDIMTHHFKQSRDVLTQSAAWTSYGDLTIKPSGYQEITTLVKQHHLFNPPAYDDFVEPSLYKEASRS
>NC_002745.2|WP_000197961.1|191530_192292_+|ABC-transporter-permease
MTRPTNNKFILPIITFIIFLGIWEMVIIIGHYQPVLLPGPALVGKSIWTFIVTGEIFQHLAISLWRFVAGFVVALLVAIPLGFLLGRNRWLYNAIEPLFQLIRPISPIAWAPFVVLWFGIGSLPAIAIIFIAAFFPIVFNTIKGVRDIEPQYLKIAANLNLTGWSLYRNILFPGAFKQIMAGIHMAVGTSWIFLVSGEMIGAQSGLGFLIVDARNMLNLEDVLAAIFFIGLFGFIIDRFISYIEQFILRRFGE
>NC_002745.2|WP_000171645.1|192304_193336_+|acyl-CoA/acyl-ACP-dehydrogenase
MTLETLIKEQLDPHLVEVDEGTYYPRTFIQQLFVDGYFGEAALRKNAEVIEAVSQSCLTTGFCLWCQLAFSTYLENATQPHLNNDLQQQLLSGEILGATGLSNPMKSFNDLEKLNLEHTYVDGQLVVSGRMPAVSNIQEDHYFGAISKHESSDEFVMFILRANQDGITLVEKTNFLGVNGSATYQITLNQVVVPQSQIITHDAKQFAATIRPQFIAYQIPIGLGSIKSSLELIDAFSNAQNGINQYLEYDVEAFKKRYRQLREEYYAILDDGNLTSHLSELISLKKDIGYLLLDVNQASVVNGGSRAYTPYSPQVRKLKEGFFFAALTPTLRHLGKLEAELKG
>NC_002745.2|WP_001092004.1|193552_193912_+|DUF2294-domain-containing-protein
MNTIDTHTKEQQFSNLVRSYRKEYVGKGPNSIRVSFKDNWAIAHMTGVLSKVESFYLNDKRNESMLHYTRTEKIKQMYKEIDVNEMESLVGAKFVKLFTDIDLNDDEVISIFVFDKSIE
>NC_002745.2|WP_000706135.1|194085_195111_+|NAD-dependent-formate-dehydrogenase
MKIVALFPEAVEGQENQLLNTKKAIGLKTFLEERGHEFIILADNGEDLDKHLPDMDVIISAPFYPAYMTRERIEKAPNLKLAITAGVGSDHVDLAAASEHNIGVVEVTGSNTVSVAEHAVMDLLILLRNYEEGHRQSVEGEWNLSQVGNHAHELQHKTIGIFGFGRIGQLVAERLAPFNVTLQHYDPINQQDHKLSKFVSFDELVSSSDAITIHAPLTPETDNLFDKDVLSRMKKHSYLVNTARGKIVNRDALVEALASEHLQGYAGDVWYPQPAPADHPWRTMPRNAMTVHYSGMTLEAQKRIEDGVKDILERFFNHEPFQDKDIIVASGRIASKSYTAK
>NC_002745.2|WP_000826862.1|195496_196747_+|MFS-transporter
MKRLSTTLKVRLISNFLQLIITTAFIPFIALYLTDMLSQSIVGIYLVGLVVLKFPLSIISGYLIEIFPKKLLVLIYQATMVIMLVFMGVFGSHQLWQIIGFCVAYAIFTIVWGLQFPVMDTLIMDAITEDVEHYIYKISYWMTNLSVAIGALLGGLMYGYSMLLLFLIAACIFLIVLFILYIWLPQDRNQVKQSDDKRHASRYQKLQIMNIFRSYKLVLKDRNYMLLISGFSIIMMGEFSISSYIAIRLKDQFETISIGSYDITGAKMLAILLMINTVVVILLTYSISKVVLKIDFKKALITGLLIYIVGYSGLTYLNQFGLLVVFMIIATVGEIIYSPIVSEQRFKIIPKAKRGTYSAVNALGIHFSETLARLGIVLGVFLTSLQMGLYMFIVLTIGASMLVAGVFGGQKQVNTN
>NC_002745.2|WP_000605281.1|197193_204369_+|amino-acid-adenylation-domain-containing-protein
MIMGNLRFQQEYFRIYKNNTESTTHRNAYWVKLAKNVEATKMMYALSTIVQQHASIRHFFDVTTDDNLTMILHEFLPFIEIKQVPSSSANYDLEAFFKQELSTYHFNDSPLFKVKLFQFADAAYILLDFHVSIFDDSQIDIFLDDLCNAYRGNTVINNTRQHAHINRNDDKDNQDASHIALDSNYFRLENNSDIHIDSYFPIKHPFEQALYQTYLIDDMTSIDMASLAVSVYLANHIMSQQHDVTLGIHVPSHLPNDLHGNIVPLTLTIDAKDVCQRFTTDFNKCVLQNMSQLQCAKSSLSLETIFHCYHHMMSCCNDVIEDVHQIHDAHTSLADIEIFPHQHGFKIIYNSAAYDLLSIETLSDLVRNIYLQITEENGNKRTTVDELNLMTERDIQLYDDINLSLPEIDDAQTVVTLFEQQVEATPNHVAVQFDGVFITYQTLNARANDLAHRLRNQYGVEPNDRVAVIAEKSIEMIIAMIGVLKAGGAYVPIDPNYPSDRQEYILKDATPKVVITYQALYENGKQNINHIDLNKIAWKNIDNLSKCNTLEDHAYVIYTSGTTGNPKGTLIPHRGIVRLVHRNHYVPLNEETTILLSGTIAFDAATFEIYGALLNGGKLIVAKKEQLLNPIAVEQLINENDVNTMWLTSSLFNQIASERIEVLVPLKYLLIGGEVLNAKWVDLLNQKPKHPQIINGYGPTENTTFTTTYNIPNKVPNRIPIGKPILGTHVYIMQGERRCGVGIPGELCTSGFGLAAGYLNQPELTADKFIKDSNINQLMYRSGDIVRLLPDGNIDYLYRKDKQVKIRGFRIELSEVEHALERIQGINKAVVIVQNHDQDQYIVAYYEAMHTLSHNKIKSQLRMTLPEYMIPVNFMHIEQIPITINGKLDKKALPIMDYVDTDAYVAPSTDTEHLLCQIFADILHVNQVGIHDNFFELGGHSLKATLVVNRIEASTGKRLQIGDLLQKPTVFELAQAIAKVQEQNYEVIPEAIVKDDYVLSSAQKRMYLLWKSNHKDTVYNVPFLWRLSSGLNVAQLQQAVQHLIARHEILRTQYIVVDDEVRQRIVADVVADFEEVNTHFTDEQEIMRQFVAPFNLEKPSQIRVRYIRSPLHAYLFIDTHHIINDGMSNIQLMNDLNALYQHKLLLPLKLQYKDYSEWMSHRDMTKHRQYWLSQFKDEVPILSLPTDYVRPNIKTTNGAMMSFTMNQQMRQLLQKYVEKHQITDFMFFMSVVMTLLSRYARKDDVVVGSVMSARMHKGTEQMLGMFANTLVYRGQPSPDKMWTQFLQEVKEMSLEAYEHQEYPFECLVNDLDQSHDASRNPLFDVMLVLQNNETNHAHFGHSKLTHIQPKSVTAKFDLSFIIEEDRDDYTINIEYNTDLYHSETVRHMGNQCMIMIDYILKHQDTLQICDIPNGTEELLNWVNTHVNDRMLNVPGNKSIISYFNEVVSRQGNHVALVMNDLTMTYETLRNYVDAIAHMLLSNGVGNGQRVALFTERSFEMIAAMLATVKVGASYIPIDIDFPNKRQGAILEDAKVTAVMSYGVEIETTLPVIQLENAKGFVESKENEQYDDLHGNQLENTAMLDNEMYAIYTSGTTGMPKGVAIRQRNLLNLVHAWSTELQLGDNEVFLQHANIVFDASVMEIYCCLLNGHTLVIPDREERVNPEQLQQLINKHRVTVASIPLQMCSIMEDFYIEKLITGGATSTASFVKYIEKHCGTYFNAYGPSESTVITSYWSHHCGDLIPETIPIGKPLSNIQVYIMSDGLLCGIGMPGELCIAGDSLAIGYINRPELMADKWQNNPFGKGKLYHSGDLARYTSDGQIEFLGRIDKQVKVNGYRIELDEIENVILAIRGISDCVVTVSHFDTHDILNAYYVGEQQVEQDLKQYLNDQLPKYMIPKTITHIDCMPLTTNDKVDTTRLPNPSPIQQSNKVYSEPSNEIEQTFVDVFGEVLKQNDVGVDDDFFELGGNSLEAMLVVSHLKRFGHHISMQTLYQYKTVRQIVNYMYQNQQSLVALPDNLSELQKIVMSRYNLGILEDSLSHRPLGNTLLTGATGFLGAYLIEALQGYSHRIYCFIRADNEEIAWYKLMTNLNDYFSEETVEMMLSNIEVIVGDFECMDDVVLPENMDTIIHAGARTDHFGDDDEFEKVNVQGTVDVIRLAQQHHARLIYVSTISVGTYFDIDTEDVTFSEADVYKGQLLTSPYTRSKFYSELKVLEAVNNGLDGRIVRVGNLTSPYNGRWHMRNIKTNRFSMVMNDLLQLDCIGVSMAEMPVDFSFVDTTARQIVALAQVNTPQIIYHVLSPNKMPVKSLLECVKRKEIELVSDESFNEILQKQDMYETIGLTSVDREQQLAMIDTTLTLKIMNHISEKWPTITNNWLYHWAQYIKTIFNK

Crispr_ID: NC_002745_2

• CRISPR_ID: NC_002745_2
• CRISPR_location: 428213-428314
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NC_002745_2

Consensus_repeat	Method
TTATGAATTGAGTATTAAATTTG	CRISPRCasFinder

spacers of NC_002745_2

>2.1|428236|56|NC_002745|CRISPRCasFinder
AAAGTAAATTACAGTTCTATAGGTTTATAAAAAATCAGTTTTTAAATCAAAGCTAT

CRISPR arrays and Neighbor proteins around NC_002745_2

CRISPR arrays

The CRISPR arrays of NC_002745_2

>merge|NC_002745|2|428213-428314|CRISPRCasFinder
TTATGAATTGAGTATTAAATTTGAAAGTAAATTACAGTTCTATAGGTTTATAAAAAATCAGTTTTTAAATCAAAGCTATATATGAATTGAGTATTAAATTTG

>NC_002745|2|2|428213-428314|CRISPRCasFinder
TTATGAATTGAGTATTAAATTTG	AAAGTAAATTACAGTTCTATAGGTTTATAAAAAATCAGTTTTTAAATCAAAGCTAT
ATATGAATTGAGTATTAAATTTG

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_002745.2|WP_000424963.1|434504_436046_+|glutamine-hydrolyzing-GMP-synthase	unknown	unknown	gnl|CDD|234614
NC_002745.2|WP_000868259.1|419286_419670_-|hypothetical-protein	unknown	unknown	unknown
NC_002745.2|WP_000956137.1|428330_429287_-|hypothetical-protein	unknown	unknown	gnl|CDD|274008
NC_002745.2|WP_000930514.1|421009_422533_-|alkyl-hydroperoxide-reductase-subunit-F	unknown	unknown	gnl|CDD|237942
NC_002745.2|WP_000551643.1|436158_436695_-|hypothetical-protein	unknown	unknown	unknown
NC_002745.2|WP_000793018.1|431707_432976_+|purine-permease	unknown	unknown	gnl|CDD|274468
NC_002745.2|WP_000211677.1|418252_418462_-|hypothetical-protein	unknown	unknown	unknown
NC_002745.2|WP_000991018.1|424444_425833_-|L-cystine-transporter	unknown	unknown	gnl|CDD|224736
NC_002745.2|WP_000394698.1|429404_430067_-|hypothetical-protein	unknown	unknown	unknown
NC_002745.2|WP_000052781.1|422548_423118_-|peroxiredoxin	unknown	unknown	gnl|CDD|211789
NC_002745.2|WP_000041880.1|437086_437791_-|type-II-toxin-antitoxin-system-PemK/MazF-family-toxin	unknown	unknown	gnl|CDD|367091
NC_002745.2|WP_001557163.1|426679_427999_+|ISL3-like-element-IS1181-family-transposase	unknown	unknown	gnl|CDD|225995
NC_002745.2|WP_000264071.1|433013_434480_+|IMP-dehydrogenase	unknown	unknown	gnl|CDD|235507
NC_002745.2|WP_000158375.1|418639_419221_+|histidine-phosphatase-family-protein	unknown	unknown	gnl|CDD|223483
NC_002745.2|WP_001792089.1|425917_426016_+|hypothetical-protein	unknown	unknown	unknown
NC_002745.2|WP_000746679.1|419939_420566_-|NDxxF-motif-lipoprotein	unknown	unknown	gnl|CDD|380196
NC_002745.2|WP_001287099.1|423609_424365_+|NADPH-dependent-oxidoreductase	unknown	unknown	gnl|CDD|380322
NC_002745.2|WP_000763767.1|430209_430617_-|general-stress-protein	unknown	unknown	gnl|CDD|378584
NC_002745.2|WP_000159787.1|438189_438462_-|transposase	unknown	unknown	gnl|CDD|225511
NC_002745.2|WP_000421410.1|431129_431708_+|xanthine-phosphoribosyltransferase	unknown	unknown	gnl|CDD|181705

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_002745.2|WP_000991018.1|424444_425833_-|L-cystine-transporter	gnl|CDD|224736	COG1823, COG1823, Predicted Na+/dicarboxylate symporter [General function prediction only].	0
NC_002745.2|WP_000956137.1|428330_429287_-|hypothetical-protein	gnl|CDD|274008	TIGR02168, Chromosome_partition_protein_Smc, chromosome segregation protein SMC, common bacterial type. SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins].	0.00265416
NC_002745.2|WP_000930514.1|421009_422533_-|alkyl-hydroperoxide-reductase-subunit-F	gnl|CDD|237942	PRK15317, PRK15317, alkyl hydroperoxide reductase subunit F; Provisional.	0
NC_002745.2|WP_000159787.1|438189_438462_-|transposase	gnl|CDD|225511	COG2963, COG2963, Transposase and inactivated derivatives [DNA replication, recombination, and repair].	9.23077e-11
NC_002745.2|WP_000793018.1|431707_432976_+|purine-permease	gnl|CDD|274468	TIGR03173, pbuX, xanthine permease. All the seed members of this model are observed adjacent to genes for either xanthine phosphoribosyltransferase (for the conversion of xanthine to guanine, GenProp0696) or genes for the conversion of xanthine to urate and its concomitant catabolism (GenProp0640, GenProp0688, GenProp0686 and GenProp0687). A number of sequences scoring higher than trusted to this model are found in different genomic contexts, and the possibility exist that these transport related compounds in addition to or instead of xanthine itself. The outgroup to this family are sequences which are characterized as uracil permeases or are adjacent to established uracil phosphoribosyltransferases.	2.06593e-169
NC_002745.2|WP_000424963.1|434504_436046_+|glutamine-hydrolyzing-GMP-synthase	gnl|CDD|234614	PRK00074, guaA, GMP synthase; Reviewed.	0
NC_002745.2|WP_000052781.1|422548_423118_-|peroxiredoxin	gnl|CDD|211789	TIGR03137, AhpC, peroxiredoxin. This peroxiredoxin (AhpC, alkylhydroperoxide reductase subunit C) is one subunit of a two-subunit complex with subunit F(TIGR03140). Usually these are found as an apparent operon. The gene has been characterized in Bacteroides fragilis, where it is important in oxidative stress defense. This gene contains two invariant cysteine residues, one near the N-terminus and one near the C-terminus, each followed immediately by a proline residue. [Cellular processes, Detoxification, Cellular processes, Adaptations to atypical conditions].	1.50623e-124
NC_002745.2|WP_000041880.1|437086_437791_-|type-II-toxin-antitoxin-system-PemK/MazF-family-toxin	gnl|CDD|367091	pfam02452, PemK_toxin, PemK-like, MazF-like toxin of type II toxin-antitoxin system. PemK is a growth inhibitor in E. coli known to bind to the promoter region of the Pem operon, auto-regulating synthesis. This family represents the toxin molecule of a typical bacterial toxin-antitoxin system pairing. The family includes a number of different toxins, such as MazF, Kid, PemK, ChpA, ChpB and ChpAK.	5.38181e-08
NC_002745.2|WP_001557163.1|426679_427999_+|ISL3-like-element-IS1181-family-transposase	gnl|CDD|225995	COG3464, COG3464, Transposase and inactivated derivatives [DNA replication, recombination, and repair].	1.75686e-114
NC_002745.2|WP_000264071.1|433013_434480_+|IMP-dehydrogenase	gnl|CDD|235507	PRK05567, PRK05567, inosine 5'-monophosphate dehydrogenase; Reviewed.	0
NC_002745.2|WP_000421410.1|431129_431708_+|xanthine-phosphoribosyltransferase	gnl|CDD|181705	PRK09219, PRK09219, xanthine phosphoribosyltransferase; Validated.	9.01486e-119
NC_002745.2|WP_000746679.1|419939_420566_-|NDxxF-motif-lipoprotein	gnl|CDD|380196	NF033193, lipo_NDxxF, NDxxF motif lipoprotein. Members of this family are lipoproteins, about 200 amino acids long in precursor form, found in Staphylococcus aureus, Bacillus cereus, and various other Firmicutes. The protein family is named for one of its several highly conserved motifs.	1.15385e-71
NC_002745.2|WP_001287099.1|423609_424365_+|NADPH-dependent-oxidoreductase	gnl|CDD|380322	cd02146, NfsA-like, nitroreductase similar to Escherichia coli NfsA. This family contains NADPH-dependent flavin reductase and oxygen-insensitive nitroreductase. These enzymes are homodimeric flavoproteins that contain one FMN per monomer as a cofactor. Flavin reductase catalyzes the reduction of flavin by using NADPH as an electron donor. Oxygen-insensitive nitroreductase, such as NfsA protein in Escherichia coli, catalyzes reduction of nitrocompounds using NADPH as electron donor.	4.50551e-88
NC_002745.2|WP_000763767.1|430209_430617_-|general-stress-protein	gnl|CDD|378584	pfam11181, YflT, Heat induced stress protein YflT. YflT is a heat induced protein.	2.17298e-12
NC_002745.2|WP_000158375.1|418639_419221_+|histidine-phosphatase-family-protein	gnl|CDD|223483	COG0406, phoE, Broad specificity phosphatase PhoE and related phosphatases [General function prediction only].	2.4566e-49

Protein sequences

>NC_002745.2|WP_001557163.1|426679_427999_+|ISL3-like-element-IS1181-family-transposase
MCNDTLELLRIKDENIKYINQEIDVIIKGKKATVVNAVLTYKPSACYCCGVKNEGQIHKHGKRVSRITLLKTQGYNTYLNLAKQRFKCLECNGTFTAKTSIVDESCFISRCVTQKVIEEATKVKTEIDTAEDNCISPSTVSRIRTKAANSLRIKPFNCLPEHIAMDEFKSVKNVTGSMSFIFIDNDTHDVIDILENRTTRFLRAYFERFDLKNRQQVKTVTIDMYEPYVRLFRDLFPNAAIIFDRFHIVQHLNRELNKYRVQVMNEYRNKKGPNYTIFKNNWKVLLMDTSKTIFSKYRWNKSFKAYKRSSDIVEFMLSKDDILRRSYELVQGLRKDLRLCNWPKFINRLNSVSKKSVSKGVWKVVKYYRKHQRMLRNTIYYPAFNNGAIEGINNKIKLIKRISFGYRNFNNFKARIMMIFSLYKGEKKKTTKPNNGLAA
>NC_002745.2|WP_001792089.1|425917_426016_+|hypothetical-protein
MQLNVNMMKFDRWHKGICKQIVLNLVEKGEKG
>NC_002745.2|WP_000991018.1|424444_425833_-|L-cystine-transporter
MNAFLTLINIIVLVIFIVILHMMARKHISFAKRVFTALGIGIVFGVLLHLVYGTHSNVITSTSDWFNIVGQGYVALLQMIVMPLIFISIVAAFTKIQIGEKFAKIGSLIFIFLIGTVTIAAIVGVVYALVFGLDASTINLGNAEQARGSEIAKQAKDLTAHTLPQQILELLPKNPFLDFTGQRATSTIAVVIFASFIGFAYLRVARKQPDHGELLKRAIDAIYSLVMAIVTFVLRLTPYGVLAIMANTLSTSDFGAIWTLGKFLIASYAALITMYIIHLIILSLLGISPIRYVKKTLEVLIFAFTSRSSAGALPLNVQTQTRRLGVPEGIANFAATFGLSIGQNGCAGIYPAMLAIMVAPVANVEIDLQFIVTLIAVVIISSFGVAGVGGGATFASILVLSTLNLPVALAGVLISVEPLIDMGRTALNVNDSMLAGTGTAKLTKHWDKDTFESNDNAALTSH
>NC_002745.2|WP_001287099.1|423609_424365_+|NADPH-dependent-oxidoreductase
MSDYVYNLVKKHHSVRKFKNKPLSEDVVKKLVEAGQSASTSSFLQAYSIIGIDDEKIKENLREVSGQPYVVENGYLFVFVIDYYRHHLVDQHAETDMENAYGSTEGLLVGAIDAALVAENIAVTAEDMGYGIVFLGSLRNDVERVREILDLPDYVFPVFGMAVGEPADDENGAAKPRLPFDHVFHHNKYHADKETQYAQMADYDQTISEYYDQRTNGNRKETWSQQIEMFLGNKARLDMLEQLQKSGLIQR
>NC_002745.2|WP_000052781.1|422548_423118_-|peroxiredoxin
MSLINKEILPFTAQAFDPKKDQFKEVTQEDLKGSWSVVCFYPADFSFVCPTELEDLQNQYEELQKLGVNVFSVSTDTHFVHKAWHDHSDAISKITYTMIGDPSQTITRNFDVLDEATGLAQRGTFIIDPDGVVQASEINADGIGRDASTLAHKIKAAQYVRKNPGEVCPAKWEEGAKTLQPGLDLVGKI
>NC_002745.2|WP_000930514.1|421009_422533_-|alkyl-hydroperoxide-reductase-subunit-F
MLNADLKQQLKQLLELMEGNVEFVASLGSDEKSKELKELLTEISDMSPRLSLSEKSLKRTPSFSVNRPGEETGVTFAGIPLGHEFNSLVLAILQVSGRAPKEKQSIIDQIKNLEGSFHFETFISLTCQKCPDVVQALNLMSVINPNITHSMIDGAVFREESENIMAVPAVFLNGEEFGNGRMTIQDILSKLGSTADASEFENKEPYDVLIVGGGPASGSAAIYTARKGLRTGIVADRIGGQVNDTAGIENFITVKETTGSEFSSNLAAHIDQYDIDAMTGIRATDIEKTDEAIKVTLENGAVLESKTVIIATGAGWRKLNIPGEEQLINKGVAFCPHCDGPLFENKDVAVIGGGNSGVEAAIDLAGIVNHVTLFEFASELKADNVLQDRLRSLSNVDIKTNAKTTEVVGEDHVTGIRYEDMSTGEEHLLNLDGIFVQIGLLPNTSWLKDAVELNERGEIVIDRNNNTNVPGIFAAGDVTDQKNKQIIISMGAGANAALNAFDYIIRN
>NC_002745.2|WP_000746679.1|419939_420566_-|NDxxF-motif-lipoprotein
MKKRLLLSTFLASALILTGCASDQSDNEDHHTSTGIHAPKSAKKLETKDIFNSDKKNSDISDAEMKQAIEKYLSVNSDILDNKYIMQHKLDKQIDSQTKVTEKQAETLSHLSNLAVKNDLHFKKFVTENNIPKEYKKPVELMMNYFKALNSTIANVDEDIEKLSYQPQNKINVVDVPTKYAGDVNKKQQDKIKDFLKSKGIKSDVIDK
>NC_002745.2|WP_000868259.1|419286_419670_-|hypothetical-protein
MKVRITFIILAILSTIVCLFLAAMYPTGPNTVTFEQPYLFTLNIILMVLVALPSLVLAIYDYMSFRISSAILQFLGAISWFFLSLILSLTQFTPFTLASFITSIILFISAIITLAIGGKSVDKNDSH
>NC_002745.2|WP_000158375.1|418639_419221_+|histidine-phosphatase-family-protein
MTIYLVRHGESKSNYDNKHFRSYFCGQLDVPLTDTGTKSADDLCDYFKEKQIKHVYVSDLLRTQQTFEHIFPYDIASTTTPLLRERSLGVFEGEYKDEISANPKYEKYFNDPNFKDFRHSFSQKAPEGESYEDVYQRVEHFMNHVVNEDTQKDDIVIVAHQVVIRCLMVYFNKVSREEAVDLKVENCKPYIIE
>NC_002745.2|WP_000211677.1|418252_418462_-|hypothetical-protein
MTTQSFIFMNIILLDGATQRHPFFICQILAFLFPKFPHINLLLFYPILSTFSNIIIHIDHFHANKKDDN
>NC_002745.2|WP_000956137.1|428330_429287_-|hypothetical-protein
MLTKEFAQRVELSEKQVRKIVQHLEERGYQLSKTEYRGREATDFKEEDIELFKDIADKVKQTNSYDLAFDELEKEKDFLQVIVKNDDKNLPTNQNVAQLVEDLRLEIQKMREERHLLGQMMNQVHQQQQELKELQNQLTSKIDSNSESLKAIQTSQEAIQEAQASQAKVLAESTNKVEKNAVTEDKADSKDSKVAGVNTSTDAKTDTKAENAGDGTATKVDKEDQISATEAIEKASVEQSKNENAAETSNKEATVDADAQHDAEQQVAEAHAEASKQATSNDSLEAKAENDSTASQSEMSEPKPQEEKKGFFARLFNL
>NC_002745.2|WP_000394698.1|429404_430067_-|hypothetical-protein
MEFKTIQSVKDPHYNEALKLYDTKLNLSLTEDKRIIKRSLENNKTENDYVFIVGLENDVVVSLATAHYEATTNSAFLIYLFAKDLPNHDELMTQTLHQIEHELNLLSNLVHSRSINFLMMEVPKEPADLTQDNGLIIEHRRQFLYEHQFERQTEIDYIHPTNDGHTKKVDLFLKKNIKLTKDIYGTSVKSNYILKYVFANGIAREIIYALLEEMDLRKPF
>NC_002745.2|WP_000763767.1|430209_430617_-|general-stress-protein
MADITVVNDTGELYNVINQKKSEGYLESELTIISKSKLHLNDLHDSEISLISTSGTFSDRMTKLLTGEDGEHAVLSRYNLAPDELEKYKQLILDDKMLVVAVRDKSSHKEVQEHNSAYEEIDITHFAEASKGPKA
>NC_002745.2|WP_000421410.1|431129_431708_+|xanthine-phosphoribosyltransferase
MELLGQKVKEDGVVIDEKILKVDGFLNHQIDAKLMNEVGRTFYEQFKDKGITKILTIEASGIAPAIMAALHFDVPCLFAKKAKPSTLTDGYYETSIHSFTKNKTSTVIVSKEFLSEEDTVLIIDDFLANGDASLGLYDIAQQANAKTAGIGIVVEKSFQNGHQRLEEAGLTVSSLCKVASLEGNKVTLVGEE
>NC_002745.2|WP_000793018.1|431707_432976_+|purine-permease
MKNLILSVQHLLAMYAGAILVPIIVGTSLKFTPEQIAYLVTVDIFMCGVATFLQANKVTGTGLPIVLGCTFTAVAPMILIGQTKGIDVLYGSLFLSGILVIIIAPFFSHLVKFFPPVVTGSVVTIIGINLMPVAMNYLAGGQGAKDYGDVKNILLGLMTLIIILVLQRFTTGFIKSIAILIGLVLGTIGAGLLGMVDINQVNHAGWLGIPVPFRFSGFSFDVTSTLVFFILAIVSLIESTGVYHALSEITGKKLERKDFRKGYTAEGLAIVLGSIFNSFPYTAYSQNVGLVSLSGAKKNNVIYGMVVLLLICGCIPKLGALANIIPLPVLGGAMIAMFGMVMAYGVSILGHIDFKNQNNLLIIAVSVGLGTGISAVPQAFKGLGEQFAWLTQNGIVLGAISAIILNFFFNGIKYKQTEENVK
>NC_002745.2|WP_000264071.1|433013_434480_+|IMP-dehydrogenase
MWESKFAKESLTFDDVLLIPAQSDILPKDVDLSVQLSDKVKLNIPVISAGMDTVTESKMAIAMARQGGLGVIHKNMGVEEQADEVQKVKRSENGVISNPFFLTPEESVYEAEALMGKYRISGVPIVDNKEDRNLVGILTNRDLRFIEDFSIKIVDVMTQENLITAPVNTTLEEAEKILQKHKIEKLPLVKDGRLEGLITIKDIEKVIEFPNAAKDEHGRLLVAAAIGISKDTDIRAQKLVEAGVDVLVIDTAHGHSKGVIDQVKHIKKTYPEITLVAGNVATAEATKDLFEAGADIVKVGIGPGSICTTRVVAGVGVPQITAIYDCATEARKHGKAIIADGGIKFSGDIIKALAAGGHAVMLGSLLAGTEESPGATEIFQGRQYKVYRGMGSLGAMEKGSNDRYFQEDKAPKKFVPEGIEGRTAYKGALQDTIYQLMGGVRAGMGYTGSHDLRELREEAQFTRMGPAGLAESHPHNIQITKESPNYSF
>NC_002745.2|WP_000424963.1|434504_436046_+|glutamine-hydrolyzing-GMP-synthase
MEMAKEQELILVLDFGSQYNQLITRRIREMGVYSELHDHEISIEEIKKMNPKGIILSGGPNSVYEEGSFTIDPEIYNLGIPVLGICYGMQLTTKLLGGKVERANEREYGKAIINAKSDELFAGLPAEQTVWMSHSDKVIEIPEGFEVIADSPSTDYAAIEDKKRRIYGVQFHPEVRHTEYGNDLLNNFVRRVCDCKGQWTMENFIEIEIEKIRQRVGDRRVLCAMSGGVDSSVVAVLLHKAIGDQLTCIFVDHGLLRKGEGDMVMEQFGEGFNMNIIRVNAKDRFMNKLKGVSDPEQKRKIIGNEFVYVFDDEASKLKGVDFLAQGTLYTDVIESGTKTAQTIKSHHNVGGLPEDMEFELIEPINTLFKDEVRKLGIELGIPEHLVWRQPFPGPGLGIRVLGEITEDKLEIVRESDAILRQVIREEGLEREIWQYFTVLPNIQSVGVMGDYRTYDHTVGIRAVTSIDGMTSDFARIDWEVLQKISSRIVNEVDHVNRVVYDITSKPPSTIEWE
>NC_002745.2|WP_000551643.1|436158_436695_-|hypothetical-protein
MHNKNEFNKKLKDFIGSDKRMALVKGYINEYKLTTVLRALNNSDYTKGTIHTRSIGNLKQIVDNRIIPKNITQNKIFKLSNLTLEVNLYERNTIYHGDFAIYYPVESALIIETDTPRLINHINNNPVQKIFIITTNDWSFNTLELEKIVDETIIYDLKQEDPKQYEILYKNKHGKLPY
>NC_002745.2|WP_000041880.1|437086_437791_-|type-II-toxin-antitoxin-system-PemK/MazF-family-toxin
MSKNINQANSKLNTSNKKLKQAYSKSDSKNMKVIYMPHWLEFYSIAIHSDVTSNKKRYYKSFSRGTVVYVKLGSNIGSEFSGNHFCVILDNKDNKGKETVTIVPLSSKGNKNYLKLNESVLNLTATDLKKQIIDISSKVQALTQKYRDIDIKLSTEDKKLLSNLNQKANELYRVIGVYSKHKGKDTYVNISAITTISKRRISKINDSDPTGTIIISEDDMNEIEKQLKIKFFSN
>NC_002745.2|WP_000159787.1|438189_438462_-|transposase
MTKERRTFSSEFKLQMVRLYKNGKLKNEIIRKYDLKPSIISNSIKQHQNTGPFNHQDNLKSDEKELIKLRKEVQHLKMEHDVLKQILKLI

Crispr_ID: NC_002745_3

• CRISPR_ID: NC_002745_3
• CRISPR_location: 777160-777242
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NC_002745_3

Consensus_repeat	Method
CCAATTTCTACAGACAATGCAAGTTGG	CRISPRCasFinder

spacers of NC_002745_3

>3.1|777187|29|NC_002745|CRISPRCasFinder
CGGGGCCCCAACATAGAGAAATTGGAACG

CRISPR arrays and Neighbor proteins around NC_002745_3

CRISPR arrays

The CRISPR arrays of NC_002745_3

>merge|NC_002745|3|777160-777242|CRISPRCasFinder
CCAATTTCTACAGACAATGCAAGTTGGCGGGGCCCCAACATAGAGAAATTGGAACGCCAATTTCTACAGACAATGCAAGTTGG

>NC_002745|3|3|777160-777242|CRISPRCasFinder
CCAATTTCTACAGACAATGCAAGTTGG	CGGGGCCCCAACATAGAGAAATTGGAACG
CCAATTTCTACAGACAATGCAAGTTGG

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_002745.2|WP_000022323.1|764761_765766_+|biotin-dependent-carboxyltransferase-family-protein	unknown	unknown	gnl|CDD|224895
NC_002745.2|WP_000663030.1|775071_776130_+|histidinol-phosphate-transaminase	unknown	unknown	gnl|CDD|235106
NC_002745.2|WP_000562498.1|785693_786665_+|class-1b-ribonucleoside-diphosphate-reductase-subunit-beta	unknown	unknown	gnl|CDD|275027
NC_002745.2|WP_000499195.1|786845_787001_+|hypothetical-protein	unknown	unknown	unknown
NC_002745.2|WP_000708690.1|764067_764778_+|allophanate-hydrolase-subunit-1	unknown	unknown	gnl|CDD|224960
NC_002745.2|WP_001068501.1|781442_782309_-|DMT-family-transporter	unknown	unknown	gnl|CDD|223769
NC_002745.2|WP_001797134.1|763773_763980_+|hypothetical-protein	unknown	unknown	unknown
NC_002745.2|WP_000525106.1|768449_770333_+|ABC-F-family-ATP-binding-cassette-domain-containing-protein	unknown	unknown	gnl|CDD|223562
NC_002745.2|WP_000193751.1|779076_780582_-|peptide-MFS-transporter	unknown	unknown	gnl|CDD|225646
NC_002745.2|WP_000589248.1|772347_773325_+|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl|CDD|224050
NC_002745.2|WP_000429006.1|777889_778807_-|diacylglycerol-kinase-family-lipid-kinase	unknown	unknown	gnl|CDD|224513
NC_002745.2|WP_000855514.1|783470_785576_+|class-1b-ribonucleoside-diphosphate-reductase-subunit-alpha	unknown	unknown	gnl|CDD|236069
NC_002745.2|WP_000197262.1|776468_777011_+|5'-3'-deoxyribonucleotidase	unknown	unknown	gnl|CDD|226895
NC_002745.2|WP_000930014.1|780922_781423_-|NADPH-dependent-7-cyano-7-deazaguanine-reductase-QueF	unknown	unknown	gnl|CDD|223851
NC_002745.2|WP_000180991.1|773317_774832_+|ABC-transporter-permease/substrate-binding-protein	unknown	unknown	gnl|CDD|270328
NC_002745.2|WP_000098285.1|766239_768180_+|polyglycerol-phosphate-lipoteichoic-acid-synthase-LtaS	unknown	unknown	gnl|CDD|224287
NC_002745.2|WP_000983677.1|770344_772126_+|DNA-helicase-RecQ	unknown	unknown	gnl|CDD|273594
NC_002745.2|WP_000876318.1|787039_788011_+|ABC-transporter-permease	unknown	unknown	gnl|CDD|226965
NC_002745.2|WP_031760357.1|778897_778999_+|hypothetical-protein	unknown	unknown	unknown
NC_002745.2|WP_000692521.1|783109_783508_+|class-Ib-ribonucleoside-diphosphate-reductase-assembly-flavoprotein-NrdI	unknown	unknown	gnl|CDD|224694

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_002745.2|WP_000022323.1|764761_765766_+|biotin-dependent-carboxyltransferase-family-protein	gnl|CDD|224895	COG1984, DUR1, Allophanate hydrolase subunit 2 [Amino acid transport and metabolism].	1.25641e-144
NC_002745.2|WP_000663030.1|775071_776130_+|histidinol-phosphate-transaminase	gnl|CDD|235106	PRK03158, PRK03158, histidinol-phosphate aminotransferase; Provisional.	0
NC_002745.2|WP_000562498.1|785693_786665_+|class-1b-ribonucleoside-diphosphate-reductase-subunit-beta	gnl|CDD|275027	TIGR04171, ribonucleotide-diphosphate_reductase_subunit_beta, ribonucleoside-diphosphate reductase, class 1b, beta subunit. Members of this family are NrdF, the beta subunit of class 1b ribonucleotide reductase. This form uses a dimanganese moiety associated with a tyrosine radical to reduce the cellular requirement for iron. [Purines, pyrimidines, nucleosides, and nucleotides, 2'-Deoxyribonucleotide metabolism].	2.30551e-164
NC_002745.2|WP_000708690.1|764067_764778_+|allophanate-hydrolase-subunit-1	gnl|CDD|224960	COG2049, DUR1, Allophanate hydrolase subunit 1 [Amino acid transport and metabolism].	1.34598e-94
NC_002745.2|WP_001068501.1|781442_782309_-|DMT-family-transporter	gnl|CDD|223769	COG0697, RhaT, Permeases of the drug/metabolite transporter (DMT) superfamily [Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only].	3.04233e-10
NC_002745.2|WP_000197262.1|776468_777011_+|5'-3'-deoxyribonucleotidase	gnl|CDD|226895	COG4502, COG4502, 5'(3')-deoxyribonucleotidase [Nucleotide transport and metabolism].	3.14113e-108
NC_002745.2|WP_000525106.1|768449_770333_+|ABC-F-family-ATP-binding-cassette-domain-containing-protein	gnl|CDD|223562	COG0488, Uup, ATPase components of ABC transporters with duplicated ATPase domains [General function prediction only].	0
NC_002745.2|WP_000193751.1|779076_780582_-|peptide-MFS-transporter	gnl|CDD|225646	COG3104, PTR2, Dipeptide/tripeptide permease [Amino acid transport and metabolism].	1.22605e-172
NC_002745.2|WP_000589248.1|772347_773325_+|ABC-transporter-ATP-binding-protein	gnl|CDD|224050	COG1125, OpuBA, ABC-type proline/glycine betaine transport systems, ATPase components [Amino acid transport and metabolism].	1.28246e-155
NC_002745.2|WP_000429006.1|777889_778807_-|diacylglycerol-kinase-family-lipid-kinase	gnl|CDD|224513	COG1597, LCB5, Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase [Lipid metabolism / General function prediction only].	7.55646e-79
NC_002745.2|WP_000692521.1|783109_783508_+|class-Ib-ribonucleoside-diphosphate-reductase-assembly-flavoprotein-NrdI	gnl|CDD|224694	COG1780, NrdI, Protein involved in ribonucleotide reduction [Nucleotide transport and metabolism].	5.52807e-56
NC_002745.2|WP_000930014.1|780922_781423_-|NADPH-dependent-7-cyano-7-deazaguanine-reductase-QueF	gnl|CDD|223851	COG0780, COG0780, Enzyme related to GTP cyclohydrolase I [General function prediction only].	7.91282e-79
NC_002745.2|WP_000180991.1|773317_774832_+|ABC-transporter-permease/substrate-binding-protein	gnl|CDD|270328	cd13610, PBP2_ChoS, Substrate-binding domain ChoS of an osmoregulated ABC-type transporter and related proteins; type 2 periplasmic-binding protein fold. Osmoprotectant binding lipoprotein ChoS of Lactococcus lactis is predicted to be involved in uptake of compatible solutes such as choline and glycine betaine, but the relative substrate preference is not known. To counteract the efflux of water, microorganisms accumulate the compatible solutes for a sustained adjustment to high osmolarity surroundings. ChoS belongs to the type 2 periplasmic binding fold protein superfamily (PBP2). The PBP2 proteins are typically comprised of two globular subdomains connected by a flexible hinge and bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap.	3.03165e-152
NC_002745.2|WP_000098285.1|766239_768180_+|polyglycerol-phosphate-lipoteichoic-acid-synthase-LtaS	gnl|CDD|224287	COG1368, MdoB, Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily [Cell envelope biogenesis, outer membrane].	0
NC_002745.2|WP_000983677.1|770344_772126_+|DNA-helicase-RecQ	gnl|CDD|273594	TIGR01389, recQ, ATP-dependent DNA helicase RecQ. The ATP-dependent DNA helicase RecQ of E. coli is about 600 residues long. This model represents bacterial proteins with a high degree of similarity in domain architecture and in primary sequence to E. coli RecQ. The model excludes eukaryotic and archaeal proteins with RecQ-like regions, as well as more distantly related bacterial helicases related to RecQ. [DNA metabolism, DNA replication, recombination, and repair].	0
NC_002745.2|WP_000876318.1|787039_788011_+|ABC-transporter-permease	gnl|CDD|226965	COG4606, CeuB, ABC-type enterochelin transport system, permease component [Inorganic ion transport and metabolism].	1.32603e-150
NC_002745.2|WP_000855514.1|783470_785576_+|class-1b-ribonucleoside-diphosphate-reductase-subunit-alpha	gnl|CDD|236069	PRK07632, PRK07632, ribonucleotide-diphosphate reductase subunit alpha; Validated.	0

Protein sequences

>NC_002745.2|WP_000197262.1|776468_777011_+|5'-3'-deoxyribonucleotidase
MTRKSIAIDMDEVLADTLGEIIDAVNFRADLGIKMEALNGQKLKHVIPEHDGLITEVLREPGFFRHLKVMPHAQEVVKKLTEHYDVYIATAAMDVPTSFSDKYEWLLEFFPFLDPQHFVFCGRKNIVKADYLIDDNPRQLEIFTGTPIMFTAVHNINDDRFERVNSWKDVEQYFLDNIEK
>NC_002745.2|WP_000663030.1|775071_776130_+|histidinol-phosphate-transaminase
MKEQLNQLSAYQPGLSPRALKEKYGIEGDLYKLASNENLYGPSPKVKEAISAHLDELYYYPETGSPTLKAAISKHLNVDQSRILFGAGLDEVILMISRAVLTPGDTIVTSEATFGQYYHNAIVESANVIQVPLKDGGFDLEGILKEVNEDTSLVWLCNPNNPTGTYFNHESLDSFLSQVPPHVPVIIDEAYFEFVTAEDYPDTLALQQKYDNAFLLRTFSKAYGLAGLRVGYVVASEHAIEKWNIIRPPFNVTRISEYAAVAALEDQQYLKEVTHKNSVERERFYQLPQSEYFLPSQTNFIFVKTKRVNELYEALLNVGCITRPFPTGVRITIGFKEQNDKMLEVLSNFKYE
>NC_002745.2|WP_000180991.1|773317_774832_+|ABC-transporter-permease/substrate-binding-protein
MTNFFDILSERKGQLFSTMIEHIQISFIALLIATAIAVPLGILLTKTKTISEIVMNIAAILQTIPSLALLGLMIPLFGIGRVPAIIALVVYALLPILRNTYTGIKEVDPSLIEAAKGIGMKPFRRLTKVELPIAMPVIMAGVRTAMVLIIGTATLAALIGAGGLGDLILLGIDRNNASLILLGAIPAALLAIIFDLILRFMAKLSYKKLLMTLGVIVMIIILAIAIPMFAQKGDKITLAGKLGSEPSIITNMYKILIEEETKNTVEVKDGMGKTAFLFNALKSDDIDGYLEFTGTVLGELTKEPLKSKEEKKVYEQAKQSLEKKYQMTMLKPMKYNNTYALAVKRDFAKQHNIRTIGDLNKVKDQLKPGFTLEFNDRPDGYKAVQKAYNLNLDNIRTMEPKLRYQAINKGNINLIDAYSTDAELKQYDMVVLKDDKHVFPPYQGAPLFKESFLKKHPEIKKPLNKLENKISDEDMQMMNYKVTVKNEDPYTVAKDYLKAKGLIK
>NC_002745.2|WP_000589248.1|772347_773325_+|ABC-transporter-ATP-binding-protein
MIKFKNVTKRYGKHVAVDNISFNINEGEFFVLIGPSGCGKTTTLKMINRLIHLSEGYIYFKDKPISDYPVYEMRWDIGYVLQQIALFPHMTIKENIAQVPQMKKWKEKDIDKRVDELLDMVGLEPEKYKNRKPDELSGGQRQRVGVIRALAADPPVILMDEPFSALDPISREKLQDDLIELQTKIKKTIIFVTHDIQEAMKLGDKICLLNEGHIEQIDTPEGFKNNPQSEFVKQFMGSHLEDDAPCVEENAIIRDLDIMKPIDEVTSMSAYPIVYDNQPIEVLYQHLSESERVIVMQEDSVGQYVIDRKDIFKYLSQKKEVAQHD
>NC_002745.2|WP_000983677.1|770344_772126_+|DNA-helicase-RecQ
MMQQTLSHYFGYETFRPGQEEIISKVLDHRNVLGVLPTGGGKSICYQVPGLLLGGTTIVISPLISLMKDQVDQLKAMGIQAAFLNSSLTQKEQQRIEKALSNGEIQFLYVAPERFENRYFLNMLQRIKIHLVAFDEAHCISKWGHDFRPSYQNVISKVFTLPQDFTIIALTATATVEVQQDIREKLNIAQTDQIKTSTKRRNLIFKVNPTYQRQKFILDYIKTHDEDAGIIYCSTRKQVEELQEALESQKIESVIYHAGLSNKEREEAQNDFLFDRVKVVVATNAFGMGIDKSNVRFVIHYNMPGDLESYYQEAGRAGRDGLKSECILLFSERDINLHEYFITVSQADDDYKDKMGEKLTKMIQYTKTKKCLEATIVHYFEPNEKLEECEQCSNCVQQDKSYNMTQEAKMIISCIARMKQQESYSVIIQVLRGESTDYIKYKGYDQISTHGLMKGYTTSELSHLIDELRFKGFLNENDEILMCDTSIKKLLSNEVEVFTTPFKQKATEKVFINTVEGVDRVLFSQLVEVRKKLSDKLTIAPVSIFSDYTLEEFAKRKPASKQDMINIDGVGSYKLKHYCPAFLETIQNYKAKV
>NC_002745.2|WP_000525106.1|768449_770333_+|ABC-F-family-ATP-binding-cassette-domain-containing-protein
MGMEAYKIEHLNKSYADKTIFDNLDLSISEGEKIGLVGINGTGKSTLLKVIGGIDDDFTANVMHPNQYRIRYSSQKQDLNEDMTVFDAVLSSDTTTLRIIKQYEQAVQAYADDQSDKLFKRMIDAQDAMDQHDAWDYNAEIKTILSKLGIHDTTKYIKELSGGQQKRVVLAKTLIEQPDLLLLDEPTNHLDFESISWLINYVKQYPHTVLFVTHDRYFLNEVSTRIIELNRGKLASYPGNYESYIEMRAEREVTLQKQQQKQRALYKEELAWMRAGAKARTTKQQARINRFNDLENEVNQQYKDDKGELNLAYSRLGKQVFELEDLSKAINDKVLFEHLTEIIQKGERIGVVGPNGAGKTTLLNILSGEDQQFEGKLKTGQTVKVAYFKQTDETLDRDIRMIDYLREESEVAKEKDGTSVSITQLLERFLFPSATHGKKVYKLSGGEQKRLYLLRLLVHQPNVLLLDEPTNDLDTETLTILEDYIHTFGGTVITVSHDRYFLNKVAQSYWFIHDGQMEKIIGTFEDYESYKKSLDKNKSTLKQQSKSYTTVRKKNGLSYKEKLEYEQLMKRIEQAEVRMEEIDVLMIEASADYGKIKELNEEKEQLEIQYDLDITRWSELEEIKEQQ
>NC_002745.2|WP_000098285.1|766239_768180_+|polyglycerol-phosphate-lipoteichoic-acid-synthase-LtaS
MSSQKKKISLFAFFLLTVITITLKTYFSYYVDFSLGVKGLVQNLILLMNPYSLVALVLSVFLFFKGKKAFWFMFIGGFLLTFLLYANVVYFRFFSDFLTFSTLNQVGNVESMGGAVSASFKWYDFVYFIDTLVYLFILIFKTKWLDTKAFSKKFVPVVMAASVALFFLNLAFAETDRPELLTRTFDHKYLVKYLGPYNFTVYDGVKTIENNQQKALASEDDLTKVLNYTKQRQTEPNPEYYGVAKKKNIIKIHLESFQTFLINKKVNGKEVTPFLNKLSSGKEQFTYFPNFFHQTGQGKTSDSEFTMDNSLYGLPQGSAFSLKGDNTYQSLPAILDQKQGYKSDVMHGDYKTFWNRDQVYKHFGIDKFYDATYYDMSDKNVVNLGLKDKIFFKDSANYQAKMKSPFYSHLITLTNHYPFTLDEKDATIEKSNTGDATVDGYIQTARYLDEALEEYINDLKKKGLYDNSVIMIYGDHYGISENHNNAMEKLLGEKITPAKFTDLNRTGFWIKIPGKSGGINNEYAGQVDVMPTILHLAGIDTKNYLMFGTDLFSKGHNQVVPFRNGDFITKDYKYVNGKIYSNKNNELITTQPADFEKNKKQVEKDLEMSDNVLNGDLFRFYKNPDFKKVNPSKYKYETGPKANSKK
>NC_002745.2|WP_000022323.1|764761_765766_+|biotin-dependent-carboxyltransferase-family-protein
MSIIIEKSGLFSSFQDFGRRGYEHDGVIPCGALDTLAHEIANRLVANDKNEATLEMTNKMATIRFTEPTLIALAGGNVKAYTEHMTISPYKLYLLDKGDVLKFRETSYTSRVYLAVGGGFELDAWLGSNSTDFNVKIGGFKGRTLQDGDEIKLKRDYTARHHKLFENLAHTKQTDWGIDGYALSFNYMSDVFHVVKNKGTEDFKEDAIQRFVKHDYKVTSKANRMGMMLEGEKIKAFYEDMPPYQTVKKGTIQIKRDGTPIILLNDHYTLGSYPQIGTIASYHLTKLAQKPQGSRLKFQFIDILTAEKNLVKYSNWLNQLFHGIEYRMQLEMMK
>NC_002745.2|WP_000708690.1|764067_764778_+|allophanate-hydrolase-subunit-1
MKIYSQGDQAIVVAIEKEVSKSLTEDLLTLRSYLIEQNYPFIIEIVPSESDMMIVYDARDMIKHHNIQSPFLYMKALIESIHLNIKHDFNQQDLIEIPIVYGSKYGPDIESLLKHYKIKLETFIELHSKTQYFVSMMGYSPGFPYLTGLNKKLYINHTSKQKKFIPAGSVVLEGKKCGIVTTDTINDWLVIGYTPLSLFNPKESDFARLKLGDNIKFRPINENELEVGAFKDVNHN
>NC_002745.2|WP_001797134.1|763773_763980_+|hypothetical-protein
MIIVYIVLLLILVYVNYRLVNRLLSENRIYVVRLIVTITTVISFILVYALIHELMPFVVRAMDLMYHQ
>NC_002745.2|WP_000429006.1|777889_778807_-|diacylglycerol-kinase-family-lipid-kinase
MENKYTHGVLFYHEHSGLKNINQGIGEVTTALSSICKHLSIQLSENEGDIIKYCQEIKTKNYAKDVDILFILGGDGTVNELINGVMSHDLQLPIGILPGGTFNDFTKTLNIAPNHKQASEQMISAQVGTYDVIKINNQYALNFVGLGLIVQNAENVQDGSKDIFGKLSYIGSTVKTLLNPTQFNYQLSIDDKTYSGETTMILTANGPFIGGSRIPLTDLSPQDGELNTFIFNEQSFSILNDIFKKRDSMNWNEITQGIEHIPGKKISLTTDPAMKVDIDGEISLETPIDIEVIPNAIQLLTVNDL
>NC_002745.2|WP_031760357.1|778897_778999_+|hypothetical-protein
MVITDIDVYRVGRENIVIAVYNEHIKLLFILIS
>NC_002745.2|WP_000193751.1|779076_780582_-|peptide-MFS-transporter
MTQQNSHGNQIQDIPQTGFFGHPRGLGVLFFVEFWERFSYYGMRALLIFYMYFAVTDNGLGIDKTTAMSIMSVYGSLIYMTSIPGGWIADRITGTRGATLLGAVFIIIGHICLSLPFALIGLFTSMFFIIIGSGLMKPNISNIVGRLYPENDRRMDAGFVIFYMSVNMGALLSPIILQHFVNVKNFHGGFLIAAVGMALGLVWYVLFNRKNLGSVGMKPTNPLTPAEKKKYGLIIGSVVLAIVLIIVIGALTNSLSFNLVSNTVLVLGIALPIIYFTLIIRSKDVTDTERSRVKAFIPLFILGMVFWAIQEQGSNVLNIYGIEHSDMKLNLFGWKTNFGEAIFQSINPLFILLLAPIISLLWQKLGTKQPSLPVKFAIGTFLAGASYILIGIVGYASGSSNFSVNWVILSYIICVIGELCLSPTGNSAAVKLAPKAFNAQMMSIWYLTNASAQAINGTLVKLIEPLGQTNYFIFLGVVAIIVTTIVLAFSPLIIKAMKGIR
>NC_002745.2|WP_000930014.1|780922_781423_-|NADPH-dependent-7-cyano-7-deazaguanine-reductase-QueF
MAHGRQQDELQDITLLGNQDNTYNFDYRPDVLESFDNKHQGRDYFVKFNCPEFTSLCPITGQPDFATIYISYIPNVKMVESKSLKLYLFSFRNHGDFHEDCMNIIMNDLIELMDPHYIEVWGKFTPRGGISIDPYTNYGRPNSKYEKMAEHRLMNHDLYPEKIDNR
>NC_002745.2|WP_001068501.1|781442_782309_-|DMT-family-transporter
MNPKVKGIIAILISAIGFSFMSVFFRLAGDLPVFQKSLARNLVAMFIPLFFLYKYHQPMFGRLSSQPLLITRSTLGLIGVLLNIYAIDHMVLSDADSLMKLNPFWTILLSIVFLHEKVRKYQITAMIIAILGMLLIVKPEFSSSMIPSLAGLFSGIFAASAYTCVRALSSREAPYTIVFYFSLFSVIVLIPFTAYTYEPMSQMQILYLLGAGLAAAVGQIGVTLAYSFAAAKDISIFTYASIIFTAILGFVLFGESPDFYATLGYVVIIGASYYMFEKARRDAKIIKK
>NC_002745.2|WP_000692521.1|783109_783508_+|class-Ib-ribonucleoside-diphosphate-reductase-assembly-flavoprotein-NrdI
MKIIYFSFTGNVRRFIKRTELENTLEITAENCMEPVHEPFIIVTGTIGFGEVPEPVQSFLEVNHQYIRGVAASGNRNWGLNFAKAGRTISEEYNVPLLMKFELHGKNKDVIEFKNKVGNFNENHGREKVQSY
>NC_002745.2|WP_000855514.1|783470_785576_+|class-1b-ribonucleoside-diphosphate-reductase-subunit-alpha
MKTMEEKKYNHIELNNEVTKRREDGFFSLEKDQEALVAYLEEVKDKTIFFDTEIERLRYLVDNDFYFNVFDIYSEADLIEITDYAKSISFNFASYMSASKFFKDYALKTNDKSQYLEDYNQHVAIVALYLANGNKAQAKQFISAMVEQRYQPATPTFLNAGRARRGELVSCFLLEVDDSLNSINFIDSTAKQLSKIGGGVAINLSKLRARGEAIKGIKGVAKGVLPIAKSLEGGFSYADQLGQRPGAGAVYLNIFHYDVEEFLDTKKVNADEDLRLSTISTGLIVPSKFFDLAKEGKDFYMFAPHTVKEEYGVTLDDIDLEKYYDDMVANPNVEKKKKNAREMLNLIAQTQLQSGYPYLMFKDNANRVHPNSNIGQIKMSNLCTEIFQLQETSIINDYGIEDEIKRDISCNLGSLNIVNVMESGKFRDSVHSGMDALTVVSDVANIQNAPGVRKANSELHSVGLGVMNLHGYLAKNKIGYESEEAKDFANIFFMMMNFYSIERSMEIAKERGIKYQDFEKSDYANGKYFEFYTTQEFEPQFEKVRELFDGMAIPTSEDWKKLQQDVEQYGLYHAYRLAIAPTQSISYVQNATSSVMPIVDQIERRTYGNAETFYPMPFLSPQTMWYYKSAFNTDQMKLIDLIATIQTHIDQGISTILYVNSEISTRELARLYVYAHYKGLKSLYYTRNKLLSVEECTSCSI
>NC_002745.2|WP_000562498.1|785693_786665_+|class-1b-ribonucleoside-diphosphate-reductase-subunit-beta
MIAVNWNTQEDMTNMFWRQNISQMWVETEFKVSKDIASWKTLSEAEQDTFKKALAGLTGLDTHQADDGMPLVMLHTTDLRKKAVYSFMAMMEQIHAKSYSHIFTTLLPSSETNYLLDEWVLEEPHLKYKSDKIVANYHKLWGKEASIYDQYMARVTSVFLETFLFFSGFYYPLYLAGQGKMTTSGEIIRKILLDESIHGVFTGLDAQHLRNELSESEKQKADQEMYKLLNDLYLNEESYTKMLYDDLGITEDVLNYVKYNGNKALSNLGFEPYFEEREFNPIIENALDTTTKNHDFFSVKGDGYVLALNVEALQDDDFVFDNK
>NC_002745.2|WP_000499195.1|786845_787001_+|hypothetical-protein
MFYFTLSKQNTHSEKLNFSLIANINKIDTKLFERLLKLWSKNATINEKYYQ
>NC_002745.2|WP_000876318.1|787039_788011_+|ABC-transporter-permease
MKYLLKGNILLLLLILLTIISLFIGVSELSIKDLLHLTESQRNILFSSRIPRTMSILIAGSSLALAGLIMQQMMQNKFVSPTTAGTMEWAKLGILIALLFFPTGHILLKLVFAVICSICGTFLFVKIIDFIKVKDVIFVPLLGIMMGGIVASFTTFISLRTNAVQSIGNWLNGNFAIITSGRYEILYLSIPLLALTYLFANHFTIVGMGKDFTNNLGLSYEKLINIALFITATITALVVVTVGTLPFLGLVIPNIISIYRGDHLKNAIPHTMMLGAIFVLFSDIVGRIVVYPYEINIGLTIGVFGTIIFLILLMKGRKNYAQQ

Crispr_ID: NC_002745_4

• CRISPR_ID: NC_002745_4
• CRISPR_location: 818107-818185
• CRISPR_type: Unclear
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NC_002745_4

Consensus_repeat	Method
TGTAGAATTTCTTTTCGAAATTCT	CRISPRCasFinder

spacers of NC_002745_4

>4.1|818131|31|NC_002745|CRISPRCasFinder
CTGTGTTGGGGCCCCGCCAACTTGCATTGCC

CRISPR arrays and Neighbor proteins around NC_002745_4

CRISPR arrays

The CRISPR arrays of NC_002745_4

>merge|NC_002745|4|818107-818185|CRISPRCasFinder
TGTAGAATTTCTTTTCGAAATTCTCTGTGTTGGGGCCCCGCCAACTTGCATTGCCTGTAGAATTTCTTTTCGAAATTCT

>NC_002745|4|4|818107-818185|CRISPRCasFinder
TGTAGAATTTCTTTTCGAAATTCT	CTGTGTTGGGGCCCCGCCAACTTGCATTGCC
TGTAGAATTTCTTTTCGAAATTCT

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_002745.2|WP_000638419.1|812435_812672_+|CsbA-family-protein	unknown	unknown	gnl|CDD|227234
NC_002745.2|WP_001049165.1|827629_828217_+|ATP-dependent-Clp-endopeptidase-proteolytic-subunit-ClpP	unknown	unknown	gnl|CDD|178955
NC_002745.2|WP_000617735.1|805424_805997_+|ribosome-associated-translation-inhibitor-RaiA	unknown	unknown	gnl|CDD|224461
NC_002745.2|WP_000134963.1|822227_823163_+|thioredoxin-disulfide-reductase	unknown	unknown	gnl|CDD|273540
NC_002745.2|WP_000506531.1|806410_808942_+|preprotein-translocase-subunit-SecA	unknown	unknown	gnl|CDD|237259
NC_002745.2|WP_001792175.1|810520_810628_+|hypothetical-protein	unknown	unknown	unknown
NC_002745.2|WP_010956549.1|809256_810367_+|peptide-chain-release-factor-2	unknown	unknown	gnl|CDD|234799
NC_002745.2|WP_000006551.1|826121_827066_+|DNA-binding-protein-WhiA	unknown	unknown	gnl|CDD|273194
NC_002745.2|WP_001790092.1|808983_809088_+|hypothetical-protein	unknown	unknown	unknown
NC_002745.2|WP_001224793.1|820228_820714_+|acetyltransferase	unknown	unknown	gnl|CDD|100053
NC_002745.2|WP_000753319.1|810775_811615_+|CHAP-domain-containing-protein	unknown	unknown	gnl|CDD|226451
NC_002745.2|WP_000513305.1|819381_820221_+|prolipoprotein-diacylglyceryl-transferase	unknown	unknown	gnl|CDD|183527
NC_002745.2|WP_000816304.1|828459_829362_-|TIGR01777-family-protein	unknown	unknown	gnl|CDD|224015
NC_002745.2|WP_000662676.1|814933_817780_+|excinuclease-ABC-subunit-UvrA	unknown	unknown	gnl|CDD|234734
NC_002745.2|WP_000229241.1|812940_814926_+|excinuclease-ABC-subunit-UvrB	unknown	unknown	gnl|CDD|235395
NC_002745.2|WP_001248939.1|825015_826011_+|YvcK-family-protein	unknown	unknown	gnl|CDD|211689
NC_002745.2|WP_000057543.1|820721_822161_+|tetratricopeptide-repeat-protein	unknown	unknown	gnl|CDD|276808
NC_002745.2|WP_000958224.1|818443_819376_+|HPr-kinase/phosphorylase	unknown	unknown	gnl|CDD|235459
NC_002745.2|WP_000369722.1|824107_825019_+|RNase-adapter-RapZ	unknown	unknown	gnl|CDD|224574
NC_002745.2|WP_000538141.1|811788_812439_+|HD-domain-containing-protein	unknown	unknown	gnl|CDD|378993

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_002745.2|WP_000638419.1|812435_812672_+|CsbA-family-protein	gnl|CDD|227234	COG4897, CsbA, Uncharacterized protein conserved in bacteria [Function unknown].	4.73465e-34
NC_002745.2|WP_001049165.1|827629_828217_+|ATP-dependent-Clp-endopeptidase-proteolytic-subunit-ClpP	gnl|CDD|178955	PRK00277, clpP, ATP-dependent Clp protease proteolytic subunit; Reviewed.	4.59321e-148
NC_002745.2|WP_000617735.1|805424_805997_+|ribosome-associated-translation-inhibitor-RaiA	gnl|CDD|224461	COG1544, COG1544, Ribosome-associated protein Y (PSrp-1) [Translation, ribosomal structure and biogenesis].	1.13584e-37
NC_002745.2|WP_000134963.1|822227_823163_+|thioredoxin-disulfide-reductase	gnl|CDD|273540	TIGR01292, Thioredoxin_reductase, thioredoxin-disulfide reductase. This model describes thioredoxin-disulfide reductase, a member of the pyridine nucleotide-disulphide oxidoreductases (pfam00070). [Energy metabolism, Electron transport].	4.19425e-154
NC_002745.2|WP_000506531.1|806410_808942_+|preprotein-translocase-subunit-SecA	gnl|CDD|237259	PRK12904, PRK12904, preprotein translocase subunit SecA; Reviewed.	0
NC_002745.2|WP_000057543.1|820721_822161_+|tetratricopeptide-repeat-protein	gnl|CDD|276808	sd00008, TPR_YbbN, C-terminal Tetratricopeptide repeat (TPR) region of YbbN and similar motifs. The Tetratricopeptide repeat (TPR) typically contains 34 amino acids and is found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi, plants, and humans. It is present in a variety of proteins including those involved in chaperone, cell-cycle, transcription, and protein transport complexes. YbbN is a thioredoxin-like protein containing two tandem TPR repeats at the C-terminus, separated by two alpha helices. Its N-terminal thioredoxin-like domain is not a functional oxidoreductase. It functions in heat stress response and DNA synthesis as a chaperone or co-chaperone.	4.14043e-06
NC_002745.2|WP_010956549.1|809256_810367_+|peptide-chain-release-factor-2	gnl|CDD|234799	PRK00578, prfB, peptide chain release factor 2; Validated.	0
NC_002745.2|WP_000006551.1|826121_827066_+|DNA-binding-protein-WhiA	gnl|CDD|273194	TIGR00647, DNA_bind_WhiA, DNA-binding protein WhiA. This family describes a DNA-binding protein widely conserved in Gram-positive bacteria, and occasionally occurring elsewhere, such as in Thermotoga. It is associated with cell division, and in sporulating organisms with sporulation. [Cellular processes, Cell division].	7.40812e-153
NC_002745.2|WP_001248939.1|825015_826011_+|YvcK-family-protein	gnl|CDD|211689	TIGR01826, Putative_gluconeogenesis_factor, conserved hypothetical protein, cofD-related. This model represents a subfamily of conserved hypothetical proteins that forms a sister group to the family of CofD, (TIGR01819), LPPG:Fo 2-phospho-L-lactate transferase, an enzyme of cytochrome F420 biosynthesis. Both this family and TIGR01819 are within the scope of the pfam01933. [Hypothetical proteins, Conserved].	5.06652e-172
NC_002745.2|WP_000229241.1|812940_814926_+|excinuclease-ABC-subunit-UvrB	gnl|CDD|235395	PRK05298, PRK05298, excinuclease ABC subunit UvrB.	0
NC_002745.2|WP_000753319.1|810775_811615_+|CHAP-domain-containing-protein	gnl|CDD|226451	COG3942, COG3942, Surface antigen [General function prediction only].	1.97111e-42
NC_002745.2|WP_000513305.1|819381_820221_+|prolipoprotein-diacylglyceryl-transferase	gnl|CDD|183527	PRK12437, PRK12437, prolipoprotein diacylglyceryl transferase; Reviewed.	1.75588e-120
NC_002745.2|WP_000662676.1|814933_817780_+|excinuclease-ABC-subunit-UvrA	gnl|CDD|234734	PRK00349, uvrA, excinuclease ABC subunit UvrA.	0
NC_002745.2|WP_001224793.1|820228_820714_+|acetyltransferase	gnl|CDD|100053	cd04647, LbH_MAT_like, Maltose O-acyltransferase (MAT)-like: This family is composed of maltose O-acetyltransferase, galactoside O-acetyltransferase (GAT), xenobiotic acyltransferase (XAT) and similar proteins. MAT and GAT catalyze the CoA-dependent acetylation of the 6-hydroxyl group of their respective sugar substrates. MAT acetylates maltose and glucose exclusively while GAT specifically acetylates galactopyranosides. XAT catalyzes the CoA-dependent acetylation of a variety of hydroxyl-bearing acceptors such as chloramphenicol and streptogramin, among others. XATs are implicated in inactivating xenobiotics leading to xenobiotic resistance in patients. Members of this family contain a a left-handed parallel beta-helix (LbH) domain with at least 5 turns, each containing three imperfect tandem repeats of a hexapeptide repeat motif (X-[STAV]-X-[LIV]-[GAED]-X). They are trimeric in their active form.	4.85181e-30
NC_002745.2|WP_000816304.1|828459_829362_-|TIGR01777-family-protein	gnl|CDD|224015	COG1090, COG1090, Predicted nucleoside-diphosphate sugar epimerase [General function prediction only].	6.73087e-155
NC_002745.2|WP_000958224.1|818443_819376_+|HPr-kinase/phosphorylase	gnl|CDD|235459	PRK05428, PRK05428, HPr kinase/phosphorylase; Provisional.	1.22623e-170
NC_002745.2|WP_000369722.1|824107_825019_+|RNase-adapter-RapZ	gnl|CDD|224574	COG1660, COG1660, Predicted P-loop-containing kinase [General function prediction only].	4.97899e-170
NC_002745.2|WP_000538141.1|811788_812439_+|HD-domain-containing-protein	gnl|CDD|378993	pfam12917, HD_2, HD containing hydrolase-like enzyme. This is a family of bacterial and archaeal hydrolases.	6.51021e-58

Protein sequences

>NC_002745.2|WP_000662676.1|814933_817780_+|excinuclease-ABC-subunit-UvrA
MKEPSIVVKGARAHNLKDIDIELPKNKLIVMTGLSGSGKSSLAFDTIYAEGQRRYVESLSAYARQFLGQMDKPDVDTIEGLSPAISIDQKTTSKNPRSTVATVTEIYDYIRLLYARVGKPYCPNHNIEIESQTVQQMVDRIMELEARTKIQLLAPVIAHRKGSHEKLIEDIGKKGYVRLRIDGEIVDVNDVPTLDKNKNHTIEVVVDRLVVKDGIETRLADSIETALELSEGQLTVDVIDGEDLKFSESHACPICGFSIGELEPRMFSFNSPFGACPTCDGLGQKLTVDVDLVVPDKDKTLNEGAIEPWIPTSSDFYPTLLKRVCEVYKINMDKPFKKLTERQRDILLYGSGDKEIEFTFTQRQGGTRKRTMVFEGVVPNISRRFHESPSEYTREMMSKYMTELPCETCHGKRLSREALSVYVGGLNIGEVVEYSISQALNYYKNIDLSEQDQAIANQILKEIISRLTFLNNVGLEYLTLNRASGTLSGGEAQRIRLATQIGSRLTGVLYVLDEPSIGLHQRDNDRLINTLKEMRDLGNTLIVVEHDDDTMRAADYLVDIGPGAGEHGGQIVSSGTPQKVMKDKKSLTGQYLSGKKRIDVPEYRRPASDRKISIRGARSNNLKGIDVDIPLSIMTVVTGVSGSGKSSLVNEVLYKSLAQKINKSKVKPGLYDKIEGIDQLDKIIDIDQSPIGRTPRSNPATYTGVFDDIRDVFAQTNEAKIRGYQKGRFSFNVKGGRCEACKGDGIIKIEMHFLPDVYVPCEVCDGKRYNRETLEVTYKGKNIADILEMTVEEATQFFENIPKIKRKLQTLVDVGLGYVTLGQQATTLSGGEAQRVKLASELHKRSTGKSIYILDELTTGLHVDDISRLLKVLNRLVENGDTVVIIEHNLDVIKTADYIIDLGPEGGSGGGTIVATGTPEDIAQTKSSYTGKYLKEVLERDKQNTEDK
>NC_002745.2|WP_000229241.1|812940_814926_+|excinuclease-ABC-subunit-UvrB
MVEHYPFKIHSDFEPQGDQPQAIKEIVDGIKAGKRHQTLLGATGTGKTFTMSNVIKEVGKPTLIIAHNKTLAGQLYSEFKEFFPENRVEYFVSYYDYYQPEAYVPSTDTFIEKDASINDEIDQLRHSATSALFERDDVIIIASVSCIYGLGNPEEYKDLVVSVRVGMEMDRSELLRKLVDVQYTRNDIDFQRGTFRVRGDVVEIFPASKEELCIRVEFFGDEIDRIREVNYLTGEVLKEREHFAIFPASHFVTREEKLKVAIERIEKELEERLKELRDENKLLEAQRLEQRTNYDLEMMREMGFCSGIENYSVHLTLRPLGSTPYTLLDYFGDDWLVMIDESHVTLPQVRGMYNGDRARKQVLVDHGFRLPSALDNRPLKFEEFEEKTKQLVYVSATPGPYEIEHTDKMVEQIIRPTGLLDPKIEVRPTENQIDDLLSEIQTRVERNERVLVTTLTKKMSEDLTTYMKEAGIKVNYLHSEIKTLERIEIIRDLRMGTYDVIVGINLLREGIDIPEVSLVVILDADKEGFLRSNRSLIQTIGRAARNDKGEVIMYADKMTDSMKYAIDETQRRREIQMKHNEKHGITPKTINKKIHDLISATVENDENNDKAQTVIPKKMTKKERQKTIDNIEKEMKQAAKDLDFEKATELRDMLFELKAEG
>NC_002745.2|WP_000638419.1|812435_812672_+|CsbA-family-protein
MIWYFSAAFFPCVLVVLFSVITRSKWVGTILTLILIGASIYKEYFHNEWIIFIDVVSLLAGYLIIDQLEFHKHQDEDR
>NC_002745.2|WP_000538141.1|811788_812439_+|HD-domain-containing-protein
MGVHQYFKRLSDMERLIRLPGKFKYFEHNVAAHSFKVTKIAQYLATVEEYHGRKINWKSLYEKALNHDFAEVFTGDIKTPVKYASSELKKLFSQVEEEMVETFIEEEIPLQYRDVYKQRLQEGKDDSLEGQILSVADKIDLLYETFGEIQKRNPEELFFEIYEMSLETIIQFDHLASVQDFINNIIPEMLTENFIPRTELRETTMNILNKRKEENE
>NC_002745.2|WP_000753319.1|810775_811615_+|CHAP-domain-containing-protein
MKKTLTVTVSSVLAFLALNNAAHAQQHGTQVKTPVQHNYVSNVQAQTQSPTTYTVVAGDSLYKIALEHHLTLNQLYSYNPGVTPLIFPGDVISLVPQNKVKQTKAVKSPVRKASQAKKVVKQPVQQASKKVVVKQAPKQAVAKTVNVAYKPAQVQKSVPTVPVAHNYNKSVANRGNLYAYGNCTYYAFDRRAQLGRSIGSLWGNANNWNYAAKVAGFKVDKTPEVGAIFQTAAGPYGHVGVVESVNPNGTITVSEMNYAGFNVKSSRTILNPGKYNYIH
>NC_002745.2|WP_001792175.1|810520_810628_+|hypothetical-protein
MCLLKQHMQCAFSNITYGDFQGIELIVENVLNYMV
>NC_002745.2|WP_010956549.1|809256_810367_+|peptide-chain-release-factor-2
MELSEIKRNIDKYNQDLTQIRGSLDLENKETNIQEYEEMMAEPNFWDNQTKAQDIIDKNNALKAIVNGYKTLQAEVDDMDATWDLLQEEFDEEMKEDLEQEVINFKAKVDEYELQLLLDGPHDANNAILELHPGAGGTESQDWANMLFRMYQRYCEKKGFKVETVDYLPGDEAGIKSVTLLIKGHNAYGYLKAEKGVHRLVRISPFDSSGRRHTSFASCDVIPDFNNDEIEIEINPDDITVDTFRASGAGGQHINKTESAIRITHHPSGIVVNNQNERSQIKNREAAMKMLKSKLYQLKLEEQAREMAEIRGEQKEIGWGSQIRSYVFHPYSMVKDHRTNEETGKVDAVMDGDIGPFIESYLRQTMSHD
>NC_002745.2|WP_001790092.1|808983_809088_+|hypothetical-protein
MLWEESFYFTSVKYFKKCEEVVKRCYVLSFKKSV
>NC_002745.2|WP_000506531.1|806410_808942_+|preprotein-translocase-subunit-SecA
MGFLSKILDGNNKEIKQLGKLADKVIALEEKTAILTDEEIRNKTKQFQTELADIDNVKKQNDYLDKILPEAYALVREGSKRVFNMTPYKVQIMGGIAIHKGDIAEMRTGEGKTLTATMPTYLNALAGRGVHVITVNEYLSSVQSEEMAELYNFLGLTVGLNLNSKTTEEKREAYAQDITYSTNNELGFDYLRDNMVNYSEDRVMRPLHFAIIDEVDSILIDEARTPLIISGEAEKSTSLYTQANVFAKMLKQDEDYKYDEKTKAVHLTEQGADKAERMFKVENLYDVQNVDVISHINTALRAHVTLQRDVDYMVVDGEVLIVDQFTGRTMPGRRFSEGLHQAIEAKEGVQIQNESKTMASITFQNYFRMYNKLAGMTGTAKTEEEEFRNIYNMTVTQIPTNKPVQRNDKSDLIYISQKGKFDAVVEDVVEKHKAGQPVLLGTVAVETSEYISNLLKKRGIRHDVLNAKNHEREAEIVAGAGQKGAVTIATNMAGRGTDIKLGEGVEELGGLAVIGTERHESRRIDDQLRGRSGRQGDKGDSRFYLSLQDELMIRFGSERLQKMMSRLGLDDSTPIESKMVSRAVESAQKRVEGNNFDARKRILEYDEVLRKQREIIYNERNSIIDEEDSSQVVDAMLRSTLQRSINYYINTADDEPEYQPFIDYINDIFLQEGDITEDDIKGKDAEDIFEVVWAKIEAAYQSQKDILEEQMNEFERMILLRSIDSHWTDHIDTMDQLRQGIHLRSYAQQNPLRDYQNEGHELFDIMMQNIEEDTCKFILKSVVQVEDNIEREKTTEFGEAKHVSAEDGKEKVKPKPIVKGDQVGRNDDCPCGSGKKFKNCHGK
>NC_002745.2|WP_000617735.1|805424_805997_+|ribosome-associated-translation-inhibitor-RaiA
MIRFEIHGDNLTITDAIRNYIEEKIGKLERYFNDVPNAVAHVKVKTYSNSATKIEVTIPLKNVTLRAEERNDDLYAGIDLINNKLERQVRKYKTRINRKSRDRGDQEVFVAELQEMQETQVDNDAYDDNEIEIIRSKEFSLKPMDSEEAVLQMNLLGHDFFVFTDRETDGTSIVYRRKDGKYGLIQTSEQ
>NC_002745.2|WP_000958224.1|818443_819376_+|HPr-kinase/phosphorylase
MLTTEKLVETLKLDLIAGEEGLSKPIKNADISRPGLEMAGYFSHYASDRIQLLGTTELSFYNLLPDKDRAGRMRKLCRPETPAIIVTRGLQPPEELVEAAKELNTPLIVAKDATTSLMSRLTTFLEHALAKTTSLHGVLVDVYGVGVLITGDSGIGKSETALELVKRGHRLVADDNVEIRQINKDELIGKPPKLIEHLLEIRGLGIINVMTLFGAGSILTEKRIRLNINLENWNKQKLYDRVGLNEETLSILDTEITKKTIPVRPGRNVAVIIEVAAMNYRLNIMGINTAEEFSERLNEEIIKNSHKSEE
>NC_002745.2|WP_000513305.1|819381_820221_+|prolipoprotein-diacylglyceryl-transferase
MGIVFNYIDPVAFNLGPLSVRWYGIIIAVGILLGYFVAQRALVKAGLHKDTLVDIIFYSALFGFIAARIYFVIFQWPYYAENPSEIIKIWHGGIAIHGGLIGGFIAGVIVCKVKNLNPFQIGDIVAPSIILAQGIGRWGNFMNHEAHGGPVSRAFLEQLHLPNFIIENMYINGQYYHPTFLYESIWDVAGFIILVNIRKHLKLGETFFLYLTWYSIGRFFIEGLRTDSLMLTSNIRVAQLVSILLILISISLIVYRRIKYNPPLYSKVGALPWPTKKVK
>NC_002745.2|WP_001224793.1|820228_820714_+|acetyltransferase
MRKFLSKTHHHTNPLWRVYRLVKFSKVFKNVIIIEFSKFIPSMVLKRHIYKQLLNINIGNQSSIAYKVMLDIFYPELITIGSNSVIGYNVTILTHEALVDEFRYGPVTIGSNTLIGANATILPGITIGDNVKVAAGTVVSKDIPDNGFAYGNPMYIKMIRR
>NC_002745.2|WP_000057543.1|820721_822161_+|tetratricopeptide-repeat-protein
MAQKNNNVIPMTFDDAFYRKMAKQKFKQREYKRAAEYFEKVLELSPDDLEIQIDYAQCLVQLGIAKKAEHLFYDNIIYNRHLEDSFYELSQLNIEVNEPNKAFLFGINYVIVSDDQDYRDELDQMFDVKYQSEEQIELEAQLFVVQILFQYLFSQGRLKDAKNYVLHQPQEVQDHRVVRNLLAMCYLYLGEYDTAKALYEALLQEDSTDIYALCHYTLLLYNTKENEQYQKYLKILNKVVPMNDDESFKLGIVLSYLKQYRASQQLLYPLYKKGKFLSIQMYNALAYNYYYLGEEDESHYYWDKLKQISKVEIGHAPWVIENSKEVFDQHILPLLQSDDSHYRLYGIFLLDQLNGKEIVMTESIWQVLENLNNYEKLYLTYLVQGLTLNKLDFIHRGLLTLYQNELFVSENDLMVAWINQGELIIAEKVDLTDVEPYIGAFIYLYFKNQPRNVTKKQITTWLGITQYKLNKMIEFLLSI
>NC_002745.2|WP_000134963.1|822227_823163_+|thioredoxin-disulfide-reductase
MTEIDFDIAIIGAGPAGMTAAVYASRANLKTVMIERGIPGGQMANTEEVENFPGFEMITGPDLSTKMFEHAKKFGAVYQYGDIKSVEDKGEYKVINFGNKELTAKAVIIATGAEYKKIGVPGEQELGGRGVSYCAVCDGAFFKNKRLFVIGGGDSAVEEGTFLTKFADKVTIVHRRDELRAQRILQDRAFKNDKIDFIWSHTLKSINEKDGKVGSVTLTSTKDGSEETHEADGVFIYIGMKPLTAPFKDLGITNDVGYIVTKDDMTTSVPGIFAAGDVRDKGLRQIVTATGDGSIAAQSAAEYIEHLNDQA
>NC_002745.2|WP_000369722.1|824107_825019_+|RNase-adapter-RapZ
MDNNEKEKSKSELLVVTGLSGAGKSLVIQCLEDMGYFCVDNLPPVLLPKFVELMEQGNPSLRKVAIAIDLRGKELFNSLVAVVDKVKSESDVIIDVMFLEASTEKLISRYKETRRAHPLMEQGKRSLINAINDEREHLSQIRSIANFVIDTTKLSPKELKERIRRYYEDEEFETFTINVTSFGFKHGIQMDADLVFDVRFLPNPYYVVDLRPLTGLDKDVYNYVMKWKETEIFFEKLTDLLDFMIPGYKKEGKSQLVIAIGCTGGQHRSVALAERLGNYLNEVFEYNVYVHHRDAHIESGEKK
>NC_002745.2|WP_001248939.1|825015_826011_+|YvcK-family-protein
MRQIKVVLIGGGTGLSVMARGLREFPIDITAIVTVADNGGSTGKIRDEMDIPAPGDIRNVIAALSDSESVLSQLFQYRFEENQISGHSLGNLLIAGMTNITNDFGHAIKALSKILNIKGRVIPSTNTSVQLNAVMEDGEIVFGETNIPKKHKKIDRVFLEPNDVQPMEEAIDALREADLIVLGPGSLYTSVISNLCVNGISDALIHSDAPKLYVSNVMTQPGETDGYSVKDHIDAIHRQAGQPFIDYVICSTQTFNAQVLKKYEEKHSKPVEVNKAELEKESINVKTSSNLVEISENHLVRHNTKVLSTMIYDIALELISTIPFVPSDKRK
>NC_002745.2|WP_000006551.1|826121_827066_+|DNA-binding-protein-WhiA
MSFASEMKNELTRIDVDEMNAKAELSALIRMNGALSLSNQQFVINVQTENATTARRIYSLIKRVFNVEVEILVRKKMKLKKNNIYICRTKMKAKEILDELGILKDGIFTHEIDHSMIQDDEMRRSYLRGAFLAGGSVNNPETSSYHLEIFSQNESHAEGLTKLMNSYELNAKHLERKKGSITYLKEAEKISDFLSLIGGYQALLKFEDVRIVRDMRNSVNRLVNCETANLNKTVSAAMKQVESIKLIDKEIGIENLPDRLREIARIRVEHQEISLKELGEMVSTGPISKSGVNHRLRKLNDLADKIRNGEQIEL
>NC_002745.2|WP_001049165.1|827629_828217_+|ATP-dependent-Clp-endopeptidase-proteolytic-subunit-ClpP
MNLIPTVIETTNRGERAYDIYSRLLKDRIIMLGSQIDDNVANSIVSQLLFLQAQDSEKDIYLYINSPGGSVTAGFAIYDTIQHIKPDVQTICIGMAASMGSFLLAAGAKGKRFALPNAEVMIHQPLGGAQGQATEIEIAANHILKTREKLNRILSERTGQSIEKIQKDTDRDNFLTAEEAKEYGLIDEVMVPETK
>NC_002745.2|WP_000816304.1|828459_829362_-|TIGR01777-family-protein
MKQYLITGGTGMVGSQLVNEIKKSDSHITILTRHDQISNDKKISYVNWAKSGWEHKVPQNIDVVINLAGATLNKRWTPEYKQTLMLSRIQSTQALYELFKSRNKAPKVLFNASATGYYPPDLFMSYTEVYKTLPFDFLSDIVYQWERFAQQFEQLGTRVVIGRFGMILSNEGGALQTMKLPYKYYIGGKLGSGQQWYSWIHINDLIQAILFLINNESASGPFNLTAPIPERQNLFGYTLARAMHKPHETWAPSLAMRLILGQMSTVVLDTQKVLPNKIQALGFQFKYSNLKMALEDLIKE

Crispr_ID: NC_002745_5

• CRISPR_ID: NC_002745_5
• CRISPR_location: 873980-874061
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NC_002745_5

Consensus_repeat	Method
CCCCAACTTGCATTGTCTGTAGAA	CRISPRCasFinder

spacers of NC_002745_5

>5.1|874004|34|NC_002745|CRISPRCasFinder
ATTGAGAATCCAATTTCTCTTTGTTGGGGCCCAT

CRISPR arrays and Neighbor proteins around NC_002745_5

CRISPR arrays

The CRISPR arrays of NC_002745_5

>merge|NC_002745|5|873980-874061|CRISPRCasFinder
CCCCAACTTGCATTGTCTGTAGAAATTGAGAATCCAATTTCTCTTTGTTGGGGCCCATCCCCAACTTGCATTGCCTGTAGAA

>NC_002745|5|5|873980-874061|CRISPRCasFinder
CCCCAACTTGCATTGTCTGTAGAA	ATTGAGAATCCAATTTCTCTTTGTTGGGGCCCAT
CCCCAACTTGCATTGCCTGTAGAA

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_002745.2|WP_000520231.1|876615_877311_+|ABC-transporter-permease	unknown	unknown	gnl|CDD|224922
NC_002745.2|WP_001065801.1|875051_875348_+|thioredoxin-family-protein	unknown	unknown	gnl|CDD|239245
NC_002745.2|WP_001557544.1|868089_869982_+|tyrosine-type-recombinase/integrase	unknown	unknown	gnl|CDD|271187
NC_002745.2|WP_000571207.1|875597_876623_+|methionine-ABC-transporter-ATP-binding-protein	unknown	unknown	gnl|CDD|224058
NC_002745.2|WP_001072201.1|871424_872156_-|23S-rRNA-(adenine(2058)-N(6))-methyltransferase-Erm(A)	unknown	unknown	gnl|CDD|366074
NC_002745.2|WP_001006450.1|882382_883633_+|cysteine-desulfurase	unknown	unknown	gnl|CDD|131034
NC_002745.2|WP_001018962.1|874672_875059_+|topiosmerase	unknown	unknown	gnl|CDD|224572
NC_002745.2|WP_000205567.1|880969_882277_+|Fe-S-cluster-assembly-protein-SufD	unknown	unknown	gnl|CDD|223791
NC_002745.2|WP_000732324.1|877328_878150_+|MetQ/NlpA-family-ABC-transporter-substrate-binding-protein	unknown	unknown	gnl|CDD|224381
NC_002745.2|WP_001147952.1|864748_865069_-|thioredoxin-family-protein	unknown	unknown	gnl|CDD|239245
NC_002745.2|WP_000361059.1|869988_870366_+|transposase	unknown	unknown	unknown
NC_002745.2|WP_000290491.1|865726_866107_+|glycine-cleavage-system-protein-GcvH	unknown	unknown	gnl|CDD|234918
NC_002745.2|WP_000067268.1|870516_871299_+|aminoglycoside-nucleotidyltransferase-ANT(9)-Ia	unknown	unknown	gnl|CDD|184296
NC_002745.2|WP_001092058.1|872689_873352_+|methyltransferase-domain-containing-protein	unknown	unknown	gnl|CDD|225136
NC_002745.2|WP_000868132.1|867007_868093_+|tyrosine-type-recombinase/integrase	unknown	unknown	gnl|CDD|271186
NC_002745.2|WP_000168845.1|880110_880872_+|Fe-S-cluster-assembly-ATPase-SufC	unknown	unknown	gnl|CDD|223473
NC_002745.2|WP_000422908.1|864058_864598_+|nitroreductase	unknown	unknown	gnl|CDD|380312
NC_002745.2|WP_001183854.1|878931_879783_-|DUF368-domain-containing-protein	unknown	unknown	gnl|CDD|224946
NC_002745.2|WP_000752917.1|878503_878698_+|CsbD-family-protein	unknown	unknown	gnl|CDD|225777
NC_002745.2|WP_000589549.1|865212_865569_+|arsenate-reductase-family-protein	unknown	unknown	gnl|CDD|239334

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_002745.2|WP_000520231.1|876615_877311_+|ABC-transporter-permease	gnl|CDD|224922	COG2011, AbcD, ABC-type metal ion transport system, permease component [Inorganic ion transport and metabolism].	7.66296e-99
NC_002745.2|WP_001065801.1|875051_875348_+|thioredoxin-family-protein	gnl|CDD|239245	cd02947, TRX_family, TRX family; composed of two groups: Group I, which includes proteins that exclusively encode a TRX domain; and Group II, which are composed of fusion proteins of TRX and additional domains. Group I TRX is a small ancient protein that alter the redox state of target proteins via the reversible oxidation of an active site dithiol, present in a CXXC motif, partially exposed at the protein's surface. TRX reduces protein disulfide bonds, resulting in a disulfide bond at its active site. Oxidized TRX is converted to the active form by TRX reductase, using reducing equivalents derived from either NADPH or ferredoxins. By altering their redox state, TRX regulates the functions of at least 30 target proteins, some of which are enzymes and transcription factors. It also plays an important role in the defense against oxidative stress by directly reducing hydrogen peroxide and certain radicals, and by serving as a reductant for peroxiredoxins. At least two major types of functional TRXs have been reported in most organisms; in eukaryotes, they are located in the cytoplasm and the mitochondria. Higher plants contain more types (at least 20 TRX genes have been detected in the genome of Arabidopsis thaliana), two of which (types f amd m) are located in the same compartment, the chloroplast. Also included in the alignment are TRX-like domains which show sequence homology to TRX but do not contain the redox active CXXC motif. Group II proteins, in addition to either a redox active TRX or a TRX-like domain, also contain additional domains, which may or may not possess homology to known proteins.	7.01368e-14
NC_002745.2|WP_001557544.1|868089_869982_+|tyrosine-type-recombinase/integrase	gnl|CDD|271187	cd01187, INT_tnpB_C_Tn554, Putative Transposase B from transposon Tn554, C-terminal catalytic domain. This family includes putative Transposase B from transposon Tn554. It belongs to a DNA breaking-rejoining enzyme superfamily. The catalytic domain containing six conserved active site residues. The recombination reaction involves cleavage of a single strand of a DNA duplex by nucleophilic attack of a conserved tyrosine to give a 3' phosphotyrosyl protein-DNA adduct. In the second rejoining step, a terminal 5' hydroxyl attacks the covalent adduct to release the enzyme and generate duplex DNA. Many DNA breaking-rejoining enzymes also have N-terminal domains, which show little sequence or structure similarity.	6.6262e-52
NC_002745.2|WP_000571207.1|875597_876623_+|methionine-ABC-transporter-ATP-binding-protein	gnl|CDD|224058	COG1135, AbcC, ABC-type metal ion transport system, ATPase component [Inorganic ion transport and metabolism].	1.76735e-170
NC_002745.2|WP_001072201.1|871424_872156_-|23S-rRNA-(adenine(2058)-N(6))-methyltransferase-Erm(A)	gnl|CDD|366074	pfam00398, RrnaAD, Ribosomal RNA adenine dimethylase.	5.43116e-86
NC_002745.2|WP_001006450.1|882382_883633_+|cysteine-desulfurase	gnl|CDD|131034	TIGR01979, Probable_cysteine_desulfurase, cysteine desulfurases, SufSfamily. This model represents a subfamily of NifS-related cysteine desulfurases involved in FeS cluster formation needed for nitrogen fixation among other vital functions. Many cysteine desulfurases are also active as selenocysteine lyase and/or cysteine sulfinate desulfinase. This subfamily is associated with the six-gene SUF system described in E. coli and Erwinia as an FeS cluster formation system during oxidative stress. The active site Cys is this subfamily resembles GHHC with one or both His conserved. [Biosynthesis of cofactors, prosthetic groups, and carriers, Other].	0
NC_002745.2|WP_001018962.1|874672_875059_+|topiosmerase	gnl|CDD|224572	COG1658, COG1658, Small primase-like proteins (Toprim domain) [DNA replication, recombination, and repair].	2.45102e-36
NC_002745.2|WP_000205567.1|880969_882277_+|Fe-S-cluster-assembly-protein-SufD	gnl|CDD|223791	COG0719, SufB, Cysteine desulfurase activator SufB [Posttranslational modification, protein turnover, chaperones].	3.36148e-135
NC_002745.2|WP_000732324.1|877328_878150_+|MetQ/NlpA-family-ABC-transporter-substrate-binding-protein	gnl|CDD|224381	COG1464, NlpA, ABC-type metal ion transport system, periplasmic component/surface antigen [Inorganic ion transport and metabolism].	1.02861e-112
NC_002745.2|WP_001147952.1|864748_865069_-|thioredoxin-family-protein	gnl|CDD|239245	cd02947, TRX_family, TRX family; composed of two groups: Group I, which includes proteins that exclusively encode a TRX domain; and Group II, which are composed of fusion proteins of TRX and additional domains. Group I TRX is a small ancient protein that alter the redox state of target proteins via the reversible oxidation of an active site dithiol, present in a CXXC motif, partially exposed at the protein's surface. TRX reduces protein disulfide bonds, resulting in a disulfide bond at its active site. Oxidized TRX is converted to the active form by TRX reductase, using reducing equivalents derived from either NADPH or ferredoxins. By altering their redox state, TRX regulates the functions of at least 30 target proteins, some of which are enzymes and transcription factors. It also plays an important role in the defense against oxidative stress by directly reducing hydrogen peroxide and certain radicals, and by serving as a reductant for peroxiredoxins. At least two major types of functional TRXs have been reported in most organisms; in eukaryotes, they are located in the cytoplasm and the mitochondria. Higher plants contain more types (at least 20 TRX genes have been detected in the genome of Arabidopsis thaliana), two of which (types f amd m) are located in the same compartment, the chloroplast. Also included in the alignment are TRX-like domains which show sequence homology to TRX but do not contain the redox active CXXC motif. Group II proteins, in addition to either a redox active TRX or a TRX-like domain, also contain additional domains, which may or may not possess homology to known proteins.	2.4922e-24
NC_002745.2|WP_000290491.1|865726_866107_+|glycine-cleavage-system-protein-GcvH	gnl|CDD|234918	PRK01202, PRK01202, glycine cleavage system protein GcvH.	9.01516e-70
NC_002745.2|WP_000067268.1|870516_871299_+|aminoglycoside-nucleotidyltransferase-ANT(9)-Ia	gnl|CDD|184296	PRK13746, PRK13746, aminoglycoside resistance protein; Provisional.	2.99486e-84
NC_002745.2|WP_001092058.1|872689_873352_+|methyltransferase-domain-containing-protein	gnl|CDD|225136	COG2226, UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis [Coenzyme metabolism].	5.63343e-23
NC_002745.2|WP_000868132.1|867007_868093_+|tyrosine-type-recombinase/integrase	gnl|CDD|271186	cd01186, INT_tnpA_C_Tn554, Putative Transposase A from transposon Tn554, C-terminal catalytic domain. This family includes putative Transposase A from transposon Tn554. It belongs to a DNA breaking-rejoining enzyme superfamily. The catalytic domain contains six conserved active site residues. The recombination reaction involves cleavage of a single strand of a DNA duplex by nucleophilic attack of a conserved tyrosine to give a 3' phosphotyrosyl protein-DNA adduct. In the second rejoining step, a terminal 5' hydroxyl attacks the covalent adduct to release the enzyme and generate duplex DNA. Many DNA breaking-rejoining enzymes also have N-terminal domains, which show little sequence or structure similarity.	4.0175e-100
NC_002745.2|WP_000168845.1|880110_880872_+|Fe-S-cluster-assembly-ATPase-SufC	gnl|CDD|223473	COG0396, sufC, Cysteine desulfurase activator ATPase [Posttranslational modification, protein turnover, chaperones].	1.29081e-150
NC_002745.2|WP_000422908.1|864058_864598_+|nitroreductase	gnl|CDD|380312	cd02135, YdjA-like, nitroreductase family protein similar to Escherichia coli YdjA. A subfamily of the nitroreductase family containing uncharacterized proteins that are similar to nitroreductase YdjA from Escherichia coli. Nitroreductase catalyzes the reduction of nitroaromatic compounds such as nitrotoluenes, nitrofurans and nitroimidazoles. This process requires NAD(P)H as electron donor in an obligatory two-electron transfer and uses FMN as cofactor. The enzyme is typically a homodimer. Members of this family are also called NADH dehydrogenase, oxygen-insensitive NAD(P)H nitrogenase or dihydropteridine reductase.	2.10032e-49
NC_002745.2|WP_001183854.1|878931_879783_-|DUF368-domain-containing-protein	gnl|CDD|224946	COG2035, COG2035, Predicted membrane protein [Function unknown].	7.67366e-77
NC_002745.2|WP_000752917.1|878503_878698_+|CsbD-family-protein	gnl|CDD|225777	COG3237, COG3237, Uncharacterized protein conserved in bacteria [Function unknown].	5.95583e-07
NC_002745.2|WP_000589549.1|865212_865569_+|arsenate-reductase-family-protein	gnl|CDD|239334	cd03036, ArsC_like, Arsenate Reductase (ArsC) family, unknown subfamily; uncharacterized proteins containing a CXXC motif with similarity to thioredoxin (TRX)-fold arsenic reductases, ArsC. Proteins containing a redox active CXXC motif like TRX and glutaredoxin (GRX) function as protein disulfide oxidoreductases, altering the redox state of target proteins via the reversible oxidation of the active site dithiol. ArsC catalyzes the reduction of arsenate [As(V)] to arsenite [As(III)], using reducing equivalents derived from glutathione via GRX, through a single catalytic cysteine.	1.06191e-56

Protein sequences

>NC_002745.2|WP_001092058.1|872689_873352_+|methyltransferase-domain-containing-protein
MNTIESQFDKVAEDYDFVNELLNDYSFFVSNMSPKKGRALDIGCGSGLLVEKLASYYDEVVGIDISNQMLDLAKSKRQLTNTVYLNMNAEQLNFNEKFDFIVSRTTFHHLDDIASVIQQMKELLNEEGRIVILDNVSEVETPPTYVYKLGAIQEFLPHCFKFGIKNAIRIYNHNTSKSWLEHLASDKYLSEQNYYDLYEKLLPGCQFHKMGWAMGVVWTK
>NC_002745.2|WP_001072201.1|871424_872156_-|23S-rRNA-(adenine(2058)-N(6))-methyltransferase-Erm(A)
MNQKNPKDTQNFITSKKHVKEILNHTNISKQDNVIEIGSGKGHFTKELVKMSRSVTAIEIDGGLCQVTKEAVNPSENIKVIQTDILKFSFPKHINYKIYGNIPYNISTDIVKRITFESQAKYSYLIVEKGFAKRLQNLQRALGLLLMVEMDIKMLKKVPPLYFHPKPSVDSVLIVLERHQPLISKKDYKKYRSFVYKWVNREYRVLFTKNQFRQALKHANVTNINKLSKEQFLSIFNSYKLFH
>NC_002745.2|WP_000067268.1|870516_871299_+|aminoglycoside-nucleotidyltransferase-ANT(9)-Ia
MSNLINGKIPNQAIQTLKIVKDLFGSSIVGVYLFGSAVNGGLRINSDVDVLVVVNHSLPQLTRKKLTERLMTISGKIGNTDSVRPLEVTVINRSEVVPWQYPPKREFIYGEWLRGEFENGQIQEPSYDPDLAIVLAQARKNSISLFGPDSSSILVSVPLTDIRRAIKDSLPELIEGIKGDERNVILTLARMWQTVTTGEITSKDVAAEWAIPLLPKEHVTLLDIARKGYRGECDDKWEGLYSKVKALVKYMKNSIETSLN
>NC_002745.2|WP_000361059.1|869988_870366_+|transposase
MDKQVRNTTEIVRLAKQKSKKTREKVDKAISKFSIEGKVINFNSIAKEANVSKSWLYKEHDIRQRIESLRERQITANVVSKPKKSSRSEEILIKTLKRRVMELEKENKKLQNQIQKLYGDLYNKE
>NC_002745.2|WP_001557544.1|868089_869982_+|tyrosine-type-recombinase/integrase
MNASSKRKIISQSEISKKIAVMNEEMQGFWANNSWDIRKCPHPSAIELSKNPALRNRWVRFERVKNLWLRTELKYFYFYHLNNGIWNAKTVWIRKGTVINKMLDFLDLKYPSITSITEVPIEKAMTEYRTYLTKRGVRITTTNYKITANQEKTPVKANSYYVTNLKQFMEFYENFYFDGEEWDKDVWDRRNLPLPDDKVNPTQYEYTINFKGFRNTYFKQLVKRYCKLRLNVDSFSYVSDIAQRLKEFFNFLDMKFKQVQRVHQLTRVEIEAYLSELNMMGIKPSTITGRISILEGLFSTLLRLEWDDVPSKILIYSEDYPKIPRAKPRFIDEFVLEQLNSHLDKLPEYIATMTMIVQECGMRISELCTLKKGCLLEDKDGDFFLKYYQWKMKKEHIVPISKEVALLIKVREDKVSEEFPDSEYLFPRKDGSPLKQETFRGELNKLAYEQNIVDKSGEIYRFHAHAFRHTVGTRMINNGMPQHIVQKFLGHESPEMTSRYAHIFDETLKNEFTKFQEKLVTNNGDVLDLDEDNEVDDVELQWFKKNINAQVLPNGYCRLPVVAGGCPHANACLDCTHFCTSKQFLPQHEEQLERTEELLAIAKDKQWQRQVETNSRVKERLEQIIGSLTG
>NC_002745.2|WP_000868132.1|867007_868093_+|tyrosine-type-recombinase/integrase
MKVQRIEVENKPYPLYLLLDKEYQLIEPVMKFIKYLDNTGKSPNTIKAYCYHLKLLYEFMEQRGVILNDINFELLADFVGWLRYPSASNVIDLQSKKAIREETTVNTILNVVMSFLDYLSRLGEFKSIDVFKQAKGRNFKGFLHHVNKGRYQKNVLKLRVKKKQIRTLRSKEVKQIIDACHTKRDKLILMLMYEGGLRIGEVLSLRLEDIVTWDNQIHLTPRDVNVNEAYIKLRKERTIHVSKELMSLYTDYLIYEYSEELEHDYVFISLKEGYFGKPLKYQSVLDLVRRIVKRTGIEFTSHMLRHTHATQLIREGWDVAFVQKRLGHAHVQTTLNTYVHLSDQDMKNEFNKYLERKEHKK
>NC_002745.2|WP_000290491.1|865726_866107_+|glycine-cleavage-system-protein-GcvH
MAVPNELKYSKEHEWVKVEGNVATIGITEYAQSELGDIVFVELPETDDEINEGDTFGSVESVKTVSELYAPISGKVVEVNEELEDSPEFVNESPYEKAWMVKVEISDESQLEALLTAEKYSEMIGE
>NC_002745.2|WP_000589549.1|865212_865569_+|arsenate-reductase-family-protein
MIKFYQYKNCTTCKKAAKFLDEYGVSYEPIDIVQHTPTINEFKTIIANTGVEINKLFNTHGAKYRELDLKNKLQTLSDDEKLELLSSDGMLVKRPLAVMGDKITLGFKEDQYKETWLA
>NC_002745.2|WP_001147952.1|864748_865069_-|thioredoxin-family-protein
MQAIKSNESFKSIINSDTPVIVKFEAGWCPDCRAMDLWIDPIVEQYNDYQWYTVNRDELEDVVVENEVMGIPSLLVFKNGDKIAHLHSANAKSPEQVESFLAETFK
>NC_002745.2|WP_000422908.1|864058_864598_+|nitroreductase
MELQQAIANRRSVKKFKRDMHIDDALLYQAIEKAADAPNHGMREPWRVVHVPKDRLGDMSKDISKFAFPNELDKQQCHYDAVTKLGGMLLLILKTDPRQRQNDENYFAFGAYAQNLMLLLYEAGIGTCWKSPLYIYDPKVRKTLGIKKDEVLAGFLYLTDLEEDMPKAPRKNRNLITLY
>NC_002745.2|WP_001018962.1|874672_875059_+|topiosmerase
MAIVNKVIIVEGKSDKKRVQQVIAEPVNIICTHGTMSIDKLDDMIESLYDKQVFVLADSDDEGDRIRNWFKRYLSESEHIFIDKTYCQVANCPKQYLAHVLSKHGFTCKKETPLLPNINNERLVLVNE
>NC_002745.2|WP_001065801.1|875051_875348_+|thioredoxin-family-protein
MNNSLDIKDVTTFYEEDKHLIFGYTPTCGTCKVSERMLDIANEILQLPLLKIDLNFYPQFCKDMQIMSTPILLLMNKDKEVKRIYAFKSVTDLLENLK
>NC_002745.2|WP_000571207.1|875597_876623_+|methionine-ABC-transporter-ATP-binding-protein
MIELKEVVKEYRTKNKEVLAVDHVNLSIRAGSIYGVIGFSGAGKSTLIRMFNHLEAPTSGEVIIDGDHIGQLSKNGLRAKRQKVNMIFQHFNLLWSRTVLKNIMFPLEIAGVPRRRAKQKALELVELVGLKGREKAYPSELSGGQKQRVGIARALANDPTVLLCDEATSALDPQTTDEILDLLLKIREQQNLTIVLITHEMHVIRRICDEVAVMESGKVIEHGPVTQVFENPQHTVTKRFVKEDLNDDFETSLTELEPLEKDAYIVRLVFAGSTTTEPIVSSLSTAYDIKINILEANIKNTKNGTVGFLVLHIPYISSVDFGKFEKELIERQVKMEVLRHG
>NC_002745.2|WP_000520231.1|876615_877311_+|ABC-transporter-permease
MGKSFSEIINEMITMPNIQWPEVWTAIVETLYMTVVSTIFAFILGLILGVLLFLSAKGKSIGARLFYSIVSFIVNLFRAIPFIILILLLIPFTSLILGTISGPTGALPALIIGAAPFYARLVEIAFKEIDKGVIEAAWSMGANTWIVIRKVLLPEAMPALVSGITVTAIALVGSTAVAGVIGAGGLGNLAYLTGFTRNQNDVILVSTVFILIIVFIIQFIGDWLTNKLDKR
>NC_002745.2|WP_000732324.1|877328_878150_+|MetQ/NlpA-family-ABC-transporter-substrate-binding-protein
MKKLFGLILVLTFAVVLAACGNGNKSGSDDKKITVGASPAPHAEILEKAKPLLEKKGYDLDIKTINDYTTPNKLLDKGEIDANYFQHTPYLNTEKKDKGYKIVSAGDVHLEPMAVYSKKYKSLKELPKGATVYVSNNPAEQGRFLKFFVDAGLIKIKKGVKIEDAKFSDITENKKDIKFNNKQSAEFLPKIYQNEDADAVIINSNFAIEQKLNPKKDSIAVESAKDNPYANLIAVKEGHQDDKKIKALIEVLQSKDIQDFINEKYNGAVIPAK
>NC_002745.2|WP_000752917.1|878503_878698_+|CsbD-family-protein
MADESKFEQAKGNVKETVGNVTDNKNLENEGKEDKASGKAKEFVENAKEKATDFIDKVKGNKGE
>NC_002745.2|WP_001183854.1|878931_879783_-|DUF368-domain-containing-protein
MQQFKWINILKGFAMGTSDLVPGVSGGTIALLLGIYNQFIASISGIFSRRFWPSFTFLIPIIIGMLLAMGSLSNLFNYLLSQHHIPTMFFFGGLIIGIVPYLLKISNYKTSFTTKHYMMVIAGIAILIVITLMNNGDKHAGETLTLSTGLIIKYFIAGMCASSAMLLPGISGSFMLLVFGVYGTVMLAISEVVKLNFTGLPILLAVGFGVLAGFIISSKIIQYFLTHHKLMTFALIIGFVVGSLFAVFPGLPTNIVMWFVSLVVFIIGFIVSLTLGRITAENE
>NC_002745.2|WP_000168845.1|880110_880872_+|Fe-S-cluster-assembly-ATPase-SufC
MASTLEIKDLHVSIEDKEILKGVNLTINTDEIHAIMGPNGTGKSTLSSAIMGHPSYEVTKGEVLLDGVNILELEVDERAKAGLFLAMQYPSEITGVTNADFMRSAINAKREEGQEINLMQFIKKLDKNMDFLDIDKDMAQRYLNEGFSGGEKKRNEILQLMMLEPKFAILDEIDSGLDIDALKVVSKGINQMRGENFGALMITHYQRLLNYITPDKVHVMYAGKVVKSGGPELAKRLEEEGYEWVKEEFGSAE
>NC_002745.2|WP_000205567.1|880969_882277_+|Fe-S-cluster-assembly-protein-SufD
MTTDILNISEEQLVDYSKAHNEPSWMTELRKKALKLTETLEMPKPDKTKLRKWDFDSFKQHDVKGDVYQSLSQLPESVREIIDVDHSKNLVIQHNNTIAYTQVDDNASKDGVIVEGLADALMNHSDLVQKHFMKDAVTVDEHRITALHTALVNGGVFVYVPKNVVVEHPVQYVVLHDDKNASFYNHVIIVTEESAEVTYVENYLSNASGEGNQLNIISEVIAGANSNITYGSVDYMDKGFTGHIIRRGITEADASINWALGLMNEGSQIIDNTTNLFGDRSTSSLKSVVVGTGEQKINLTSKIVQYGKETDGYILKHGVMKEHASSVFNGIGYIKHGGTKSIANQESRVLMLSEHARGDANPILLIDEDDVQAGHAASVGRVDPDQLYYLMSRGISQREAERLVIHGFLDPVVRELPIEDVKRQLREVIERKVSK
>NC_002745.2|WP_001006450.1|882382_883633_+|cysteine-desulfurase
MNEVAEHSFDVNEVIKDFPILDQKVNGKRLAYLDSTATSQTPMQVLNVLEDYYKRYNSNVHRGVHTLGSLATDGYENARETVRRFINAKYFEEIIFTRGTTASINLVAHSYGDANVEEGDEIVVTEMEHHANIVPWQQLAKRKNATLKFIPMTADGELNIEDIKQTINDKTKIVAIAHISNVLGTINDVKTIAEIAHQHGAIISVDGAQAAPHMKLDMQEMNADFYSFSGHKMLGPTGIGVLFGKRELLQKMEPIEFGGDMIDFVSKYDATWADLPTKFEAGTPLIAQAIGLAEAIRYLERIGFDAIHKYEQELTIYAYEQMSAIEGIEIYGPPKDRRAGVITFNLQDVHPHDVATAVDTEGVAVRAGHHCAQPLMKWLNVSSTARASFYIYNTKEDIDQLINALKQTKEFFSYEF

Crispr_ID: NC_002745_6

• CRISPR_ID: NC_002745_6
• CRISPR_location: 1618584-1618668
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NC_002745_6

Consensus_repeat	Method
CACCCCAACTTGCATTGTCTGTAGAA	CRISPRCasFinder

spacers of NC_002745_6

>6.1|1618610|33|NC_002745|CRISPRCasFinder
ATTGGGAATCCAATTTCTCTGTGTTGGGGCCCA

CRISPR arrays and Neighbor proteins around NC_002745_6

CRISPR arrays

The CRISPR arrays of NC_002745_6

>merge|NC_002745|6|1618584-1618668|CRISPRCasFinder
CACCCCAACTTGCATTGTCTGTAGAAATTGGGAATCCAATTTCTCTGTGTTGGGGCCCACACCCCAACTTGCATTGCCTGTAGAA

>NC_002745|6|6|1618584-1618668|CRISPRCasFinder
CACCCCAACTTGCATTGTCTGTAGAA	ATTGGGAATCCAATTTCTCTGTGTTGGGGCCCA
CACCCCAACTTGCATTGCCTGTAGAA

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_002745.2|WP_001282560.1|1621305_1622280_-|DNA-polymerase-III-subunit-delta	unknown	unknown	gnl|CDD|235511
NC_002745.2|WP_001119021.1|1612238_1613378_-|molecular-chaperone-DnaJ	unknown	unknown	gnl|CDD|237656
NC_002745.2|WP_000218103.1|1617150_1618275_-|oxygen-independent-coproporphyrinogen-III-oxidase	unknown	unknown	gnl|CDD|236309
NC_002745.2|WP_000108668.1|1609189_1610536_-|tRNA-(N(6)-L-threonylcarbamoyladenosine(37)-C(2))--methylthiotransferase-MtaB	unknown	unknown	gnl|CDD|223694
NC_002745.2|WP_000048060.1|1608720_1608897_-|30S-ribosomal-protein-S21	unknown	unknown	gnl|CDD|234707
NC_002745.2|WP_001190120.1|1610542_1611295_-|16S-rRNA-(uracil(1498)-N(3))-methyltransferase	unknown	unknown	gnl|CDD|224303
NC_002745.2|WP_000627144.1|1616072_1617050_-|heat-inducible-transcription-repressor-HrcA	unknown	unknown	gnl|CDD|273017
NC_002745.2|WP_041202030.1|1607793_1608477_-|hypothetical-protein	unknown	unknown	gnl|CDD|223961
NC_002745.2|WP_000368338.1|1618840_1620664_-|elongation-factor-4	unknown	unknown	gnl|CDD|235462
NC_002745.2|WP_001019324.1|1626894_1627479_-|HD-domain-containing-protein	unknown	unknown	gnl|CDD|224627
NC_002745.2|WP_000034716.1|1613513_1615346_-|molecular-chaperone-DnaK	unknown	unknown	gnl|CDD|234715
NC_002745.2|WP_000084830.1|1625821_1626538_-|class-I-SAM-dependent-methyltransferase	unknown	unknown	gnl|CDD|379312
NC_002745.2|WP_000182211.1|1615414_1616041_-|nucleotide-exchange-factor-GrpE	unknown	unknown	gnl|CDD|237622
NC_002745.2|WP_000725167.1|1627468_1628038_-|nicotinate-(nicotinamide)-nucleotide-adenylyltransferase	unknown	unknown	gnl|CDD|273101
NC_002745.2|WP_001104607.1|1611296_1612235_-|50S-ribosomal-protein-L11-methyltransferase	unknown	unknown	gnl|CDD|283886
NC_002745.2|WP_001557362.1|1622336_1624538_-|DNA-internalization-related-competence-protein-ComEC/Rec2	unknown	unknown	gnl|CDD|225212
NC_002745.2|WP_001802022.1|1625095_1625782_-|ComEA-family-DNA-binding-protein	unknown	unknown	gnl|CDD|224472
NC_002745.2|WP_001274017.1|1621009_1621261_+|30S-ribosomal-protein-S20	unknown	unknown	gnl|CDD|178943
NC_002745.2|WP_000439693.1|1624542_1625004_-|ComE-operon-protein-2	unknown	unknown	gnl|CDD|131622
NC_002745.2|WP_001088020.1|1626540_1626894_-|ribosome-silencing-factor	unknown	unknown	gnl|CDD|223870

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_002745.2|WP_001282560.1|1621305_1622280_-|DNA-polymerase-III-subunit-delta	gnl|CDD|235511	PRK05574, holA, DNA polymerase III subunit delta; Reviewed.	1.85853e-102
NC_002745.2|WP_001119021.1|1612238_1613378_-|molecular-chaperone-DnaJ	gnl|CDD|237656	PRK14280, PRK14280, molecular chaperone DnaJ.	0
NC_002745.2|WP_000218103.1|1617150_1618275_-|oxygen-independent-coproporphyrinogen-III-oxidase	gnl|CDD|236309	PRK08599, PRK08599, oxygen-independent coproporphyrinogen III oxidase.	0
NC_002745.2|WP_000108668.1|1609189_1610536_-|tRNA-(N(6)-L-threonylcarbamoyladenosine(37)-C(2))--methylthiotransferase-MtaB	gnl|CDD|223694	COG0621, MiaB, 2-methylthioadenine synthetase [Translation, ribosomal structure and biogenesis].	0
NC_002745.2|WP_000048060.1|1608720_1608897_-|30S-ribosomal-protein-S21	gnl|CDD|234707	PRK00270, rpsU, 30S ribosomal protein S21; Reviewed.	1.15423e-10
NC_002745.2|WP_001190120.1|1610542_1611295_-|16S-rRNA-(uracil(1498)-N(3))-methyltransferase	gnl|CDD|224303	COG1385, COG1385, Uncharacterized protein conserved in bacteria [Function unknown].	1.90273e-91
NC_002745.2|WP_000627144.1|1616072_1617050_-|heat-inducible-transcription-repressor-HrcA	gnl|CDD|273017	TIGR00331, Heat-inducible_transcription_repressor_HrcA, heat shock gene repressor HrcA. HrcA represses the class I heat shock operons groE and dnaK; overproduction prevents induction of these operons by heat shock while deletion allows constitutive expression even at low temperatures. In Bacillus subtilis, hrcA is the first gene of the dnaK operon and so is itself a heat shock gene. [Regulatory functions, DNA interactions].	2.05887e-119
NC_002745.2|WP_041202030.1|1607793_1608477_-|hypothetical-protein	gnl|CDD|223961	COG1030, NfeD, Membrane-bound serine protease (ClpP class) [Posttranslational modification, protein turnover, chaperones].	3.55067e-63
NC_002745.2|WP_000368338.1|1618840_1620664_-|elongation-factor-4	gnl|CDD|235462	PRK05433, PRK05433, GTP-binding protein LepA; Provisional.	0
NC_002745.2|WP_001019324.1|1626894_1627479_-|HD-domain-containing-protein	gnl|CDD|224627	COG1713, COG1713, Predicted HD superfamily hydrolase involved in NAD metabolism [Coenzyme metabolism].	2.21948e-80
NC_002745.2|WP_000034716.1|1613513_1615346_-|molecular-chaperone-DnaK	gnl|CDD|234715	PRK00290, dnaK, molecular chaperone DnaK; Provisional.	0
NC_002745.2|WP_000084830.1|1625821_1626538_-|class-I-SAM-dependent-methyltransferase	gnl|CDD|379312	pfam13649, Methyltransf_25, Methyltransferase domain. This family appears to be a methyltransferase domain.	7.79783e-16
NC_002745.2|WP_000182211.1|1615414_1616041_-|nucleotide-exchange-factor-GrpE	gnl|CDD|237622	PRK14140, PRK14140, heat shock protein GrpE; Provisional.	3.74407e-81
NC_002745.2|WP_000725167.1|1627468_1628038_-|nicotinate-(nicotinamide)-nucleotide-adenylyltransferase	gnl|CDD|273101	TIGR00482, Probable_nicotinate-nucleotide_adenylyltransferase, nicotinate (nicotinamide) nucleotide adenylyltransferase. This model represents the predominant bacterial/eukaryotic adenylyltransferase for nicotinamide-nucleotide, its deamido form nicotinate nucleotide, or both. The first activity, nicotinamide-nucleotide adenylyltransferase (EC 2.7.7.1), synthesizes NAD by the salvage pathway, while the second, nicotinate-nucleotide adenylyltransferase (EC 2.7.7.18) synthesizes the immediate precursor of NAD by the de novo pathway. In E. coli, NadD activity is biased toward the de novo pathway while salvage activity is channeled through the multifunctional NadR protein, but this division of labor may be exceptional. The given name of this model, nicotinate (nicotinamide) nucleotide adenylyltransferase, reflects the lack of absolute specificity with respect to substrate amidation state in most species. [Biosynthesis of cofactors, prosthetic groups, and carriers, Pyridine nucleotides].	2.64141e-76
NC_002745.2|WP_001104607.1|1611296_1612235_-|50S-ribosomal-protein-L11-methyltransferase	gnl|CDD|283886	pfam06325, PrmA, Ribosomal protein L11 methyltransferase (PrmA). This family consists of several Ribosomal protein L11 methyltransferase (EC:2.1.1.-) sequences.	9.7051e-134
NC_002745.2|WP_001557362.1|1622336_1624538_-|DNA-internalization-related-competence-protein-ComEC/Rec2	gnl|CDD|225212	COG2333, ComEC, Predicted hydrolase (metallo-beta-lactamase superfamily) [General function prediction only].	3.64233e-90
NC_002745.2|WP_001802022.1|1625095_1625782_-|ComEA-family-DNA-binding-protein	gnl|CDD|224472	COG1555, ComEA, DNA uptake protein and related DNA-binding proteins [DNA replication, recombination, and repair].	1.06297e-33
NC_002745.2|WP_001274017.1|1621009_1621261_+|30S-ribosomal-protein-S20	gnl|CDD|178943	PRK00239, rpsT, 30S ribosomal protein S20; Reviewed.	1.42889e-17
NC_002745.2|WP_000439693.1|1624542_1625004_-|ComE-operon-protein-2	gnl|CDD|131622	TIGR02571, putative_dCMP_deaminase, ComE operon protein 2. This protein is found in the ComE operon for "late competence" as characterized in B. subtilis. Proteins in this family contain homology to a cytidine/deoxycytidine deaminase domain family (pfam00383), and may carry out this activity.	4.81051e-102
NC_002745.2|WP_001088020.1|1626540_1626894_-|ribosome-silencing-factor	gnl|CDD|223870	COG0799, COG0799, Uncharacterized homolog of plant Iojap protein [Function unknown].	5.95861e-47

Protein sequences

>NC_002745.2|WP_000218103.1|1617150_1618275_-|oxygen-independent-coproporphyrinogen-III-oxidase
MTVQSAYIHIPFCVRICTYCDFNKYFIQNQPVDEYLDALITEMSTAKYRNLKTMYVGGGTPTALSINQLERLLKAIRDTFTITGEYTFEANPDELTKEKVQLLEKYGVNRISMGVQTFKPELLSVLGRTHNTEDIYTSVLNAKNAGIKSISLDLMYHLPKQTIEDFEQSLDLALDMDIQHISSYGLILEPKTQFYNMYRKGLLKLPNEDLGADMYQLLMSKIEQSPFHQYEISNFALDGHESEHNKVYWFNEEYYGFGAGASGYVDGVRYTNINPVNHYIKAINKESKAILVSNKPSLTERMEEEMFLGLRLNEGVSSSRFKKKFDQSIESVFGQTINNLKEKELIVEKNDAIALTKRGKVIGNEVFEAFLIND
>NC_002745.2|WP_000627144.1|1616072_1617050_-|heat-inducible-transcription-repressor-HrcA
MITDRQLSILNAIVEDYVDFGQPVGSKTLIERHNLNVSPATIRNEMKQLEDLNYIEKTHSSSGRSPSQLGFRYYVNRLLEQTSHQKTNKLRRLNQLLVENQYDVSSALTYFADELSNISQYTTLVVHPNHKQDIINNVHLIRANPNLVIMVIVFSSGHVEHVHLASDIPFSNDKLNTISNFVTNKLTEFNQNLQDDIVSFVQSEQEEIFINKLINTMNNHISNQSNSIYMGGKVKLIDALNESNVSSIQPILQYIESNRIAELLQDISSPNINVKIGNEIDDSLSDISIVTSQYHFDETLKGQIAVIGPTAMHYQNVIQLLNRIW
>NC_002745.2|WP_000182211.1|1615414_1616041_-|nucleotide-exchange-factor-GrpE
MTNKDESVEKNTESTVEETNIKQNIDDSVEQAEESKGHLQDEAIEETSDENVIEEIDPKDQKINELQQLADENEEKYLRLYAEFENYKRRIQKENEINKTYQAQRVLTDILPAIDNIERALQIEGDDETFKSLQKGVQMVHESLINALKDNGLEVIKTEGEAFDPNIHQAVVQDDNPDFESGEITQELQKGYKLKDRVLRPSMVKVNQ
>NC_002745.2|WP_000034716.1|1613513_1615346_-|molecular-chaperone-DnaK
MSKIIGIDLGTTNSCVTVLEGDEPKVIQNPEGSRTTPSVVAFKNGETQVGEVAKRQAITNPNTVQSIKRHMGTDYKVDIEGKSYTPQEISAMILQNLKNTAESYLGEKVDKAVITVPAYFNDAERQATKDAGKIAGLEVERIINEPTAAALAYGLDKTDKDEKVLVFDLGGGTFDVSILELGDGVFEVLSTAGDNKLGGDDFDQVIIDYLVAEFKKENGVDLSQDKMALQRLKDAAEKAKKDLSGVSQTQISLPFISAGENGPLHLEVNLTRSKFEELSDSLIRRTMEPTRQAMKDAGLTNSDIDEVILVGGSTRIPAVQEAVKKEIGKEPNKGVNPDEVVAMGAAIQGGVITGDVKDVVLLDVTPLSLGIEILGGRMNTLIERNTTIPTSKSQIYSTAVDNQPSVDVHVLQGERPMAADNKTLGRFQLTDIPPAERGKPQIEVTFDIDKNGIVNVTAKDLGTNKEQRITIQSSSSLSDEEIDRMVKDAEVNAEADKKRREEVDLRNEADSLVFQVEKTLTDLGENIGEEDKKSAEEKKDALKTALEGQDIEDIKSKKEELEKVIQELSAKVYEQAAQQQQQAQGANAGQNNDSTVEDAEFKEVKDDDKK
>NC_002745.2|WP_001119021.1|1612238_1613378_-|molecular-chaperone-DnaJ
MAKRDYYEVLGISKDASKDEIKKAYRKLSKKYHPDINKEEGADEKFKEISEAYEVLSDDNKRASYDQFGHDGPQGFGGQGFNGSDFGGFSGFGGGGFEDIFSSFFGGGRQRDPNAPQKGDDLQYTMTLTFEEAVFGTTKEISIRKDVTCETCHGDGAKPGTSKKTCSYCNGAGHVAVEQNTILGRVRTEQVCPKCNGSGQEFEEACPTCHGKGTENKTVKLEVKVPEGVDNEQQIRLAGEGSPGVNGGPAGDLYVVFRVKPSETFKRDGDDIYYKLNVSFPQAALGDEIKIPTLNNEVMLTIPAGTQTGKQFRLKEKGIKNVHGYGYGDLYVDIKVVTPTKLTDRQKELMKEFAQLNGEEINEQPSNFKDRAKRFFKGE
>NC_002745.2|WP_001104607.1|1611296_1612235_-|50S-ribosomal-protein-L11-methyltransferase
MNWTELSIIINHEAVELATNILENHGSNGVVIEDSDDLINQPEDKYGEIYALKKEDYPDKGVRLKAYFNEMTYDDKLRQQIKDELLNLDELDQHNIQFSEQIIAETDWENEWKNYFHPFRASKKFTIVPSWETYAKEADEELCIELDPGMAFGTGDHPTTSMCLKAIETYVLPQHSVIDVGTGSGILSIASHLIGVKRIKALDIDEMAVSVAKENFRRNHCETLIEAVPGNLLKDETEKFDIVIANILAHIIDEMIEDAYNTLNEGGYFITSGIIKEKYEGIQSHMERVGFKIISEQHDNGWVCLVGQKVSE
>NC_002745.2|WP_001190120.1|1610542_1611295_-|16S-rRNA-(uracil(1498)-N(3))-methyltransferase
MQRYFIDQNADVSQRFFITKKEDIHHITNVMRYDVGSKIILTFNDQTVYLCEIADITSDKIAVDLKEKQNINTELPVDVTICSGLIKADKYEWLLQKATELGASSFIAVSMERSIVKLNEAKVVKKIERWQKIIKEAAEQSYRLVIPSIQFESNLKLICDTIDNYDYILIAYEEEAKDGELSNFKQTLQQFKAQDKVLMIFGPEGGLSENEISLFSNTSTVVGLGPRILRAETAPLYALSAISYEKELMG
>NC_002745.2|WP_000108668.1|1609189_1610536_-|tRNA-(N(6)-L-threonylcarbamoyladenosine(37)-C(2))--methylthiotransferase-MtaB
MSTVAFHTLGCKVNHYETEAIWQLFKEANYERVDFEANADVFVINTCTVTNTGDKKSRQIIRRAIRQNPDAVICVTGCYAQTSSAEIMEIPGVDVVVGTQDRHKLLGYIDEFRKERQPINGVGNIMKNRKYEELDVPYFTDRTRASLKIQEGCNNFCTFCIIPWARGLMRSRDPEKVVEQATQLVNSGYKEIVLTGIHTGGYGQDLKDYNLAQLLRDLETINGLERIRISSIEASQLTDEVIDVLERSTKVVRHLHIPLQSGSDTVLKRMRRKYTMDRFSERLTKLHKALPDLAVTSDVIVGFPGETEAEFQETYDFIVKHKFSELHVFPYSPRIGTPAARMDDQIDEEIKNERVHKLITLSNQLGKLYVSKFDQDVLEVIPEEQGDTEGTLVGYADNYMKVQFEGDESLIGQIVKVKITQANYPLNEGQAIKVVDFATNKSDREVLV
>NC_002745.2|WP_000048060.1|1608720_1608897_-|30S-ribosomal-protein-S21
MSKTVVRKNESLEDALRRFKRSVSKSGTIQEVRKREFYEKPSVKRKKKSEAARKRKFK
>NC_002745.2|WP_041202030.1|1607793_1608477_-|hypothetical-protein
MTTILESTAGDTWVEQVSNIIVQPIFTLILTCLTFLGFVYQLYSKKINAAGIIATLSLLILFLGFLIQGNVNMHSILIFSIGVILVVIELFVVGAVIGIIGMILITINITTLGDNLLFMLANVIVALILTIVEWVILVKIFNRKIPFLDKVILKDSTNSESGYNSHDNRSHLVGKTAQTVTDLRPAGIIFCENERIDAVSDGNFILRNKTVKILEVEGTRVVVREVD
>NC_002745.2|WP_000368338.1|1618840_1620664_-|elongation-factor-4
MDNEQRLKRRENIRNFSIIAHIDHGKSTLADRILENTKSVETRDMQDQLLDSMDLERERGITIKLNAVRLKYEAKDGNTYTFHLIDTPGHVDFTYEVSRSLAACEGAILVVDAAQGIEAQTLANVYLALDNELELLPVINKIDLPAAEPERVKQEIEDMIGLDQDDVVLASAKSNIGIEEILEKIVEVVPAPDGDPEAPLKALIFDSEYDPYRGVISSIRIVDGVVKAGDKIRMMATGKEFEVTEVGINTPKQLPVDELTVGDVGYIIASIKNVDDSRVGDTITLASRPASEPLQGYKKMNPMVYCGLFPIDNKNYNDLREALEKLQLNDASLEFEPESSQALGFGYRTGFLGMLHMEIIQERIEREFGIELIATAPSVIYQCILRDGSEVTVDNPAQMPDRDKIDKIFEPYVRATMMVPNDYVGAVMELCQRKRGQFINMDYLDDIRVNIVYELPLAEVVFDFFDQLKSNTKGYASFDYEFIENKESNLVKMDILLNGDKVDALSFIVHRDFAYERGKALVEKLKTLIPRQQFEVPVQAAIGQKIVARTNIKSMGKNVLAKCYGGDISRKRKLLEKQKAGKAKMKAVGNVEIPQDAFLAVLKMDDE
>NC_002745.2|WP_001274017.1|1621009_1621261_+|30S-ribosomal-protein-S20
MANIKSAIKRVKTTEKAEARNISQKSAMRTAVKNAKTAVSNNADNKNELVSLAVKLVDKAAQSNLIHSNKADRIKSQLMTANK
>NC_002745.2|WP_001282560.1|1621305_1622280_-|DNA-polymerase-III-subunit-delta
MSDNIVAIYGDVPELVEKQSAEIISQFLKSDRDDFNFVKYNLYEKEIAPIVEETLTLPFFSDKKAILVKNAYIFTGEKAPKDMAHNVDQLIEFIEKYDGENLIVFEIYQNKLDERKKLTKTLKKHARLKKIEQMSEEEIKKWIQSKLNENFKDIKRDALDLFIELTGINFNIVSQEIEKLILFLGDRPTINKQDVNQIINRSLEQNVFLLTEYIQKRKKEQAIHLVKDLITMKEEPIKLLALITSNYRLFYQCKILSQKGYSGQQIAKTIGVHPYRVKLALGQVRHYQLDELLNIVDACAETDYKLKSSYMDKQLILELFILSL
>NC_002745.2|WP_001557362.1|1622336_1624538_-|DNA-internalization-related-competence-protein-ComEC/Rec2
MLYVALSMIVGVLWNSSKVLSTFLFILLLYITYRKNKIVYAPISLFLIIFSSWYLHYSQQAIFNYINYIERNSQFNERAQVIQIQRQGSDTYKGRLSLKNEIYPFFLTDKKNFDLKKIESRNCIVKGQFKVNENKFVTLKLQSIVVQSCLESNRSNLIEKHKQFIMNRIYDSGIKFPDRIMALITGDVKEINEQFKERVKEIGIYHLLAVSGSHIAAIVFLIYQPLKRLNLPLFVIKGITIIVLTLYAQYTNYAPSAVRAIIMTTLVLLITKQIKIKGIQLLAFAFIIMFILNPLVVYDIGFQFSFIISFFIMLLFPFLQQLSKLQSLFIITFIAQLASFIVAIPNFHQLQWVGFLSNLIFVPYYSIILFPLSILFFITSHFIVGLTPLNYLVDLSFNFHDWLLDLFTRIKQSHFSVPKFNDWIFIIFIISVYYIFWLLAKRKYILVTFWTIIILTLLITFPTNSHHKITMLNVGQGDSILYEGGKNQNVLIDTGGKVIDDTKQPSYSISKYHILPTLNERGINELEYLILTHPHNDHIGEVEYIISHIKIKHIVIYNKGYSSNTLMLLSKLSHKYNIKLMDVRQVSSFKLGDSSFLFFDSFIPNSRDKNEYSIITMITYQNKKVLLMGDASKNNESLLLKKYNLPEIDILKVGHHGSKTSSSKEFIEMIKPKISLISSGKNNMYHLPNIEVVKRLQRIRSRIYNSQQNGQVTIDLDDNLKVDSNSYGNASGL
>NC_002745.2|WP_000439693.1|1624542_1625004_-|ComE-operon-protein-2
MERIKWEEYFMAQSHLLALRSTCQRLSVGATIVKDNRIIAGGYNGSVAGEVHCIDEGCLIEDGHCIRTIHAEMNALLQCAKQGVSTEGATIYVTHFPCLNCTKSIIQAGIKRIYYAEDYHNHEYATKLLKQSGIEFKKIPFSPEYVAKYLTKG
>NC_002745.2|WP_001802022.1|1625095_1625782_-|ComEA-family-DNA-binding-protein
MVLLYQFLLRYKDFLTQWKLYIISAVVLIMVLIGFIFWRQDDYTSRNFENKDTALKQSTSENNSLSKLEDVQVKDGDNSKNKGPVYVDVKGAVKHPNVYKMTSKDRVVDLLDKAQLLDDADVSRINLSEKLTDQKMIFIPHKGQKNVEPQIEVNSVHVKNGNTNNTKVNLNTASVSELMSVPGVGQAKANAIVEYRNQQGAFQEIDDLKKVKGFGSKTFDKLKSYFTI
>NC_002745.2|WP_000084830.1|1625821_1626538_-|class-I-SAM-dependent-methyltransferase
MSQYAEMSLVYDQLTQDQPYEKWFEIVKNHCKDESNILDIGCGTGSLTVQLEALGNVTGMDLSVDMLTVAAQKSANVNWLEGDMTSFDLQQQFDIITIFCDSLNYLQDETAVIETFINVYHHLTDSGVFIFDVHTVYKMMTLFNNQSYIDDKGDIFLAWDAVQGDLPLSVYHDMTFFIRHEDETYSRFDESHFQRTFDEKTYLSWLAQVGFKHVETFTDFNIDEHNEDTERLFFIAKK
>NC_002745.2|WP_001088020.1|1626540_1626894_-|ribosome-silencing-factor
MNSQELLAIAVDAIDNKKGEDTISLEMKGISDMTDYFVVTHGNNERQVQAIARAVKEVANEQNIEVKRMEGYNEARWILIDLADVVVHVFHKDERNYYNIEKLYQDAPLESYGQVAY
>NC_002745.2|WP_001019324.1|1626894_1627479_-|HD-domain-containing-protein
MNIEKAKRLAKEKLPEKRYNHSLRVAETAIKLAEIYDGDTSKVELAGVLHDFCKYDDLGKMYQIVRQYELGNDLLSYGSEILHGPVCAAIMEHEYGINDEEVLMAIKYHTTGRQQMTKTEKLIFIADYIEPGRTIPGVDDIRDMAYNQGSLDKTIYEISKRTVLFLIQKDITVYNKTIDCLNYYNYSDERIKDD
>NC_002745.2|WP_000725167.1|1627468_1628038_-|nicotinate-(nicotinamide)-nucleotide-adenylyltransferase
MKKIVLYGGQFNPIHTAHMIVASEVFHELQPDEFYFLPSFMSPLKKHNNFIDVQHRLTMIQMIIDELGFGDICDDEIKRGGQSYTYDTIKAFKEQHKDSELYFVIGTDQYNQLEKWYQIEYLKEMVTFVVVNRDKNSQNVENAMIAIQIPRVDISSTMIRQRVSEGKSIQVLVPKSVENYIKGEGLYEH

Crispr_ID: NC_002745_7

• CRISPR_ID: NC_002745_7
• CRISPR_location: 1653014-1653161
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 2 spacers

Consensus repeat of NC_002745_7

Consensus_repeat	Method
CTATGTTGGGGCCCCGTCCCCAACTTCCATTGCCTGT	PILER-CR

spacers of NC_002745_7

>7.1|1653055|25|NC_002745|PILER-CR
CTGTTGAAATTAGGGTTCCAATTTC
>7.2|1653121|22|NC_002745|PILER-CR
TGAAATTGGGGTTCCAATTTCT

CRISPR arrays and Neighbor proteins around NC_002745_7

CRISPR arrays

The CRISPR arrays of NC_002745_7

>merge|NC_002745|7|1653014-1653161|PILER-CR
GGGGCCCCGTCCCCAACTTCCATTGCCTGTTGAAATTAGGGTTCCAATTTCTCTGTGTTGGGGCCCCGCCAACTTCCATTGCCTGTTGAAATTGGGGTTCCAATTTCTCTATGTTGGGGCCCCGTCCCCAACTTCCATTGCCTGTAGA

>NC_002745|7|1|1653014-1653161|PILER-CR
GGGGCCCCGTCCCCAACTTCCATTGCCTGTTGAAATTAGGG	TTCCAATTTCTCTGTGTTGGGGCCC
CGCCAACTTCCATTGCCTGTTGAAATTGGGGTTCCAATTTC	TCTATGTTGGGGCCCCGTCCCC
AACTTCCATTGCCTGTAGA

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_002745.2|WP_000134779.1|1645435_1645744_-|DUF1292-domain-containing-protein	unknown	unknown	gnl|CDD|184235
NC_002745.2|WP_000985878.1|1655901_1656915_+|LLM-class-flavin-dependent-oxidoreductase	unknown	unknown	gnl|CDD|274646
NC_002745.2|WP_000682646.1|1659561_1660335_-|tRNA-threonylcarbamoyladenosine-dehydratase	unknown	unknown	gnl|CDD|224100
NC_002745.2|WP_000044799.1|1660795_1662562_-|aspartate--tRNA-ligase	unknown	unknown	gnl|CDD|234775
NC_002745.2|WP_000734075.1|1646513_1649144_-|alanine--tRNA-ligase	unknown	unknown	gnl|CDD|234701
NC_002745.2|WP_000567017.1|1651965_1652634_-|tetratricopeptide-repeat-protein	unknown	unknown	gnl|CDD|276809
NC_002745.2|WP_000939059.1|1645758_1646187_-|Holliday-junction-resolvase-RuvX	unknown	unknown	gnl|CDD|223886
NC_002745.2|WP_001283312.1|1649486_1651964_-|ATP-dependent-RecD-like-DNA-helicase	unknown	unknown	gnl|CDD|273632
NC_002745.2|WP_000137774.1|1643586_1644510_-|U32-family-peptidase	unknown	unknown	gnl|CDD|223896
NC_002745.2|WP_000009238.1|1657151_1657298_-|hypothetical-protein	unknown	unknown	unknown
NC_002745.2|WP_000342258.1|1644512_1645151_-|O-methyltransferase	unknown	unknown	gnl|CDD|226607
NC_002745.2|WP_000066097.1|1653328_1654447_-|tRNA-2-thiouridine(34)-synthase-MnmA	unknown	unknown	gnl|CDD|234664
NC_002745.2|WP_000426912.1|1646190_1646451_-|IreB-family-regulatory-phosphoprotein	unknown	unknown	gnl|CDD|180108
NC_002745.2|WP_001790559.1|1660334_1660463_-|hypothetical-protein	unknown	unknown	unknown
NC_002745.2|WP_000409157.1|1654447_1655590_-|cysteine-desulfurase	unknown	unknown	gnl|CDD|224029
NC_002745.2|WP_000704122.1|1657619_1658042_-|Rrf2-family-transcriptional-regulator	unknown	unknown	gnl|CDD|224870
NC_002745.2|WP_000648617.1|1641683_1642307_-|uridine-kinase	unknown	unknown	gnl|CDD|235492
NC_002745.2|WP_000848304.1|1642306_1643575_-|U32-family-peptidase	unknown	unknown	gnl|CDD|223896
NC_002745.2|WP_000752909.1|1657337_1657520_-|CsbD-family-protein	unknown	unknown	gnl|CDD|225777
NC_002745.2|WP_000102729.1|1658126_1659401_+|replication-associated-recombination-protein-A	unknown	unknown	gnl|CDD|237355

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_002745.2|WP_000134779.1|1645435_1645744_-|DUF1292-domain-containing-protein	gnl|CDD|184235	PRK13678, PRK13678, hypothetical protein; Provisional.	1.28539e-26
NC_002745.2|WP_000985878.1|1655901_1656915_+|LLM-class-flavin-dependent-oxidoreductase	gnl|CDD|274646	TIGR03558, oxido_grp_1, luciferase family oxidoreductase, group 1. The Pfam domain family pfam00296 is named for luciferase-like monooxygenases, but the family also contains several coenzyme F420-dependent enzymes. This protein family represents a well-resolved clade within family pfam00296 and shows no restriction to coenzyme F420-positive species, unlike some other clades within pfam00296. [Unknown function, Enzymes of unknown specificity].	1.35642e-173
NC_002745.2|WP_000682646.1|1659561_1660335_-|tRNA-threonylcarbamoyladenosine-dehydratase	gnl|CDD|224100	COG1179, COG1179, Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1 [Coenzyme metabolism].	1.59061e-126
NC_002745.2|WP_000044799.1|1660795_1662562_-|aspartate--tRNA-ligase	gnl|CDD|234775	PRK00476, aspS, aspartyl-tRNA synthetase; Validated.	0
NC_002745.2|WP_000734075.1|1646513_1649144_-|alanine--tRNA-ligase	gnl|CDD|234701	PRK00252, alaS, alanyl-tRNA synthetase; Reviewed.	0
NC_002745.2|WP_000567017.1|1651965_1652634_-|tetratricopeptide-repeat-protein	gnl|CDD|276809	sd00006, TPR, Tetratricopeptide repeat. The Tetratricopeptide repeat (TPR) typically contains 34 amino acids and is found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi, plants, and humans. It is present in a variety of proteins including those involved in chaperone, cell-cycle, transcription, and protein transport complexes. The number of TPR motifs varies among proteins. Those containing 5-6 tandem repeats generate a right-handed helical structure with an amphipathic channel that is thought to accommodate an alpha-helix of a target protein. It has been proposed that TPR proteins preferentially interact with WD-40 repeat proteins, but in many instances several TPR-proteins seem to aggregate to multi-protein complexes.	4.6095e-16
NC_002745.2|WP_000939059.1|1645758_1646187_-|Holliday-junction-resolvase-RuvX	gnl|CDD|223886	COG0816, COG0816, Predicted endonuclease involved in recombination (possible Holliday junction resolvase in Mycoplasmas and B. subtilis) [DNA replication, recombination, and repair].	3.40149e-56
NC_002745.2|WP_001283312.1|1649486_1651964_-|ATP-dependent-RecD-like-DNA-helicase	gnl|CDD|273632	TIGR01448, recD_rel, helicase, putative, RecD/TraA family. This model describes a family similar to RecD, the exodeoxyribonuclease V alpha chain of TIGR01447. Members of this family, however, are not found in a context of RecB and RecC and are longer by about 200 amino acids at the amino end. Chlamydia muridarum has both a member of this family and a RecD. [Unknown function, Enzymes of unknown specificity].	0
NC_002745.2|WP_000137774.1|1643586_1644510_-|U32-family-peptidase	gnl|CDD|223896	COG0826, COG0826, Collagenase and related proteases [Posttranslational modification, protein turnover, chaperones].	7.60817e-104
NC_002745.2|WP_000342258.1|1644512_1645151_-|O-methyltransferase	gnl|CDD|226607	COG4122, COG4122, Predicted O-methyltransferase [General function prediction only].	5.53366e-74
NC_002745.2|WP_000066097.1|1653328_1654447_-|tRNA-2-thiouridine(34)-synthase-MnmA	gnl|CDD|234664	PRK00143, mnmA, tRNA-specific 2-thiouridylase MnmA; Reviewed.	0
NC_002745.2|WP_000426912.1|1646190_1646451_-|IreB-family-regulatory-phosphoprotein	gnl|CDD|180108	PRK05473, IreB-like, IreB family regulatory phosphoprotein. IreB (EF1202) was characterized in Enterococcus faecalis as a small protein, well-conserved in the Firmicutes. It belongs to a system that includes the Ser/Thr protein kinase IreK, and phosphatase IreP, undergoes phosphorylation on threonine residues, and is involved in regulating cephalosporin resistance. This family was previously named DUF965 by Pfam model pfam06135.	3.05024e-47
NC_002745.2|WP_000409157.1|1654447_1655590_-|cysteine-desulfurase	gnl|CDD|224029	COG1104, NifS, Cysteine sulfinate desulfinase/cysteine desulfurase and related enzymes [Amino acid transport and metabolism].	0
NC_002745.2|WP_000704122.1|1657619_1658042_-|Rrf2-family-transcriptional-regulator	gnl|CDD|224870	COG1959, COG1959, Predicted transcriptional regulator [Transcription].	5.58388e-46
NC_002745.2|WP_000648617.1|1641683_1642307_-|uridine-kinase	gnl|CDD|235492	PRK05480, PRK05480, uridine/cytidine kinase; Provisional.	5.13835e-138
NC_002745.2|WP_000848304.1|1642306_1643575_-|U32-family-peptidase	gnl|CDD|223896	COG0826, COG0826, Collagenase and related proteases [Posttranslational modification, protein turnover, chaperones].	5.98972e-149
NC_002745.2|WP_000752909.1|1657337_1657520_-|CsbD-family-protein	gnl|CDD|225777	COG3237, COG3237, Uncharacterized protein conserved in bacteria [Function unknown].	4.22501e-07
NC_002745.2|WP_000102729.1|1658126_1659401_+|replication-associated-recombination-protein-A	gnl|CDD|237355	PRK13342, PRK13342, recombination factor protein RarA; Reviewed.	0

Protein sequences

>NC_002745.2|WP_000567017.1|1651965_1652634_-|tetratricopeptide-repeat-protein
MIDQQTIYQYIQNGKIEEALQALFGNIEEDPTIIENYINAGIVLADANEIEKAERFFQKALTIDPKNGVVFYNLANVYYNQQRYQEAIKLYQQALQTEIEQVDCNYMIGMAFNQLESFKLALPYLMTAAELDKDKDAEVQFQYGLVLCQLEMFNEAITQLKHVLTIDKNHVDARYNLGLALFMKNEDIDEAITHFKEAVTIDPKHLLSQHALKTFTKMKEEE
>NC_002745.2|WP_001283312.1|1649486_1651964_-|ATP-dependent-RecD-like-DNA-helicase
MSDPTLFDYSMIKGTVEAILFQNSDNFYTVLKVDTIETNEDFDTMPTVVGFLPNIVEGDVYTFKGQVVDHPRYGKQLKAETFEKEMPQTKEAIISYLSSDLFKGVGKKTAQNIVNTLGDNAINDILDDHSVLEKVSGLSKKKQKQIAEQISANQESEKIMIRLHDLGFGPKLSMAIYQFYLGDTLTILDRNPYQLIYDIKGIGFNKADQLARNIGIAYNDNERLKAALLYTLEEECIKQGHTYLPINVVIDLTVDVLNYQDEEVIEPEKLDEMLQYLNEEKRLIIDNEQVAIPSLYYSEIKSVQNLFRIKTHTNKLTEIEQSDLQMHIGEIEDANQVNYAASQKEALQTAINSKVMLLTGGPGTGKTTVIKGIVELYAEIHGLSLDYDDYVNDDYPVVLAAPTGRASKRLQESTGLEAMTIHRLIGWNQDTKPEDILENEINARLIIIDEMSMVDTWLFHQFLSAVPLDAQLIFVGDEDQLPSVGPGQVFKDLIESKAIPRVNLTEVYRQQDGSSIIELAHRMKLGQKIDITQRFHDRSFINCQANQIPTVVEKVVTSAVNKGYTMADIQVLAPMYKGNAGIKRLNQVLQDILNPKKKDTREIEFGDVVFRKGDKVLQLVNRPNDNIFNGDIGVIVGIFWAKENALNKDVLVVDFEGNEITFTKQDMMELTHAYCTSIHKSQGSEFPIVIMPIVKQYFRMLQRPILYTGLTRAKTSLVLLGDPEAFDIGLKTNGQARLTQLCTLLKNYFNSEDEEMLENTATNDTGASQTTIDDQVEAPMSSNDSGEVTSDSTKTDINVLTEATMFKIDPMINMGEITPYDFIER
>NC_002745.2|WP_000734075.1|1646513_1649144_-|alanine--tRNA-ligase
MKKLKASEIRQKYLDFFVEKGHMVEPSAPLVPIDDDTLLWINSGVATLKKYFDGRETPKKPRIVNSQKAIRTNDIENVGFTARHHTFFEMLGNFSIGDYFKQEAIEFAWEFLTSDKWMGMEPDKLYVTIHPEDMEAYNIWHKDIGLEESRIIRIEGNFWDIGEGPSGPNTEIFYDRGEAYGQDDPAEEMYPGGENERYLEVWNLVFSEFNHNKDHSYTPLPNKNIDTGMGLERMASVSQNVRTNYETDLFMPIMNEIEKVSGKQYLVNNEQDVAFKVIADHIRTIAFAISDGALPANEGRGYVLRRLLRRAVRFSQTLGINEPFMYKLVDIVADIMEPYYPNVKEKADFIKRVIKSEEERFHETLEDGLAILNELIKKAKATTNEINGKDAFKLYDTYGFPIELTEEIAVQAGLKVDMTTFESEMQQQRDRARQARQNSQSMQVQSEVLKNITSASTFVGYDTATAQTTLTHLIYNGEEVSQVEAGETVYFMLTETPFYAVSGGQVADTGIVYNDNFEIAVSEVTKAPNGQNLHKGVVQFGQVNVGATVSAEVNQNDRRDIQKNHSATHLLHAALKSVLGDHVNQAGSLVEADRLRFDFSHFGPMTNDEIDQVERLVNEEIWKGIDVNIQEMDIASAKEMGAMALFGEKYGDVVRVVNMAPFSIELCGGIHVRNTSEIGLFKIVSESGTGAGVRRIEALTGKAAFLYLEDIQEKFNTMKSQMKVKSDDQVVEKLTQLQDEEKALLKQLEQRDKEITSLKMGNIEDQVEEINGYKVLVTEVDVPNAKAIRSTMDDFKSKLQDTIIILASNVDDKVSMVATVPKSLTNNVKAGDLIKQMAPIVGGKGGGRPDMAQGGGTQPENISKSLSFIKDYIKNL
>NC_002745.2|WP_000426912.1|1646190_1646451_-|IreB-family-regulatory-phosphoprotein
MENFDKTMKFDYEELPTQDVRDVLNNVYRTLDERGYNAVNQIVGYLLSGDPAYIPRQNEARNQIRHIDRDVIMEELVSYYLKEQNK
>NC_002745.2|WP_000939059.1|1645758_1646187_-|Holliday-junction-resolvase-RuvX
MLQHKILGLDVGSRTVGIAISDIMGWTAQGLDTLRINEENNELGIDQLVDIIKKHNVGTVVIGLPKNMNNSIGFRGEASLTYKEKLLEAYPSIEIVMWDERLSTMAAERSLLEADVSRQKRKQVIDKMAAVFILQGYLDSLH
>NC_002745.2|WP_000134779.1|1645435_1645744_-|DUF1292-domain-containing-protein
MTEHNHDSQLEINNEEELLTLFDEEGNEVLYRKVLEFYHPEFKKEYVILAEEGAQSDEDDMIELVPMINEPDESGDGGKLVPIETDEEWDMIEEVVNTEMEE
>NC_002745.2|WP_000342258.1|1644512_1645151_-|O-methyltransferase
MDDLNKKYLIDLHQHQNSSIEVLREFAEGNEVPIVDRLTLDLIKQLIRMNNVKNILEIGTAIGYSSMQFASISDDIHVTTIERNETMIQYAKQNLATYHFENQVRIIEGNALEQFENVNDKVYDMIFIDAAKAQSKKFFEIYTPLLKHQGLVITDNVLYHGFVSDIGIVRSRNVRQMVKKVQDYNEWLIKQPGYTTNFLNIDDGLAISIKGE
>NC_002745.2|WP_000137774.1|1643586_1644510_-|U32-family-peptidase
MTELLVTPKSLSHMETLIDLGADAFVIGEQKFGLRLPGEFNRQQMTEAVALAHKNDKKVYAAVNGLFHNYHLDAVEDYINFLHEIRVDRIIFGDPAVVMYVKAQENPIPLHWNAETLVTNHFQCNYWGKRGASRAVLARELNLDEIINIKENSNVEIEVQVQGMTCMFQSKRMLLGNYYTFQDRQMKIERRNDEQSLLLYDEERQNNYPVYEDYNGTHIMSPNDICLIEELAPFFEAGIDSFKIDGILQTEEYINVVTEQYRQAIDLYNEDPEIYEDEKFMLIDPIEEIQPDHRPFDEGFLYKQTVY
>NC_002745.2|WP_000848304.1|1642306_1643575_-|U32-family-peptidase
MKTIEEIKSTPKTVMKKPELLAPAGNLEKLKIAVHYGADAVFLGGQEYGLRSNADNFTMEEIAEGVEFANRYGAKIYVTTNIIAHDENIEGLESYLRNLEKTGATGIIVADPLIIETCKEVAPKLEIHLSTQQSLSNYKAVEYWKEEGLDRVVLARETGAMEMREMKEKVDIEIEAFIHGAMCIAYSGRCTLSNHMTARDSNRGGCCQSCRWDYELLEVDDNGELDVFYNQGEVTPFAMSPKDLKLIESIPQMMDIGVDSLKIEGRMKSIHYIATVVSVYRKVIDAYAADPDNFKINPEWLIELDKCANRDTAPAFFEGTPGYEEQMFGQQQSKKSPFDFCGLVLDYNEDTKIATIQQRNNFKPGQEIEFFGPEIETFTQVVEAIYDEEGNSLDAARHPLQIVQIKVDRPIYPNNMMRKEIG
>NC_002745.2|WP_000648617.1|1641683_1642307_-|uridine-kinase
MKATTIIGIAGGSGSGKTTVTNEIMKNLEGHSVALLAQDYYYKDQKHLTFDERLETNYDHPFAFDNDLLIENLKDLKNGKAVEVPTYDYASHTRSDITIDFKPKDVIIVEGIFALENKVLRDMMDVKIYVDTDADLRILRRLTRDTKERGRSMDSVINQYLSVVRPMHDQFIEPTKKYADIIIPEGGSNKVAIDIMTTKIQSLVSKQ
>NC_002745.2|WP_000066097.1|1653328_1654447_-|tRNA-2-thiouridine(34)-synthase-MnmA
MSNKDIRVVVGMSGGVDSSVTAHVLKEQGYDVIGIFMKNWDDTDENGVCTATEDYNDVIEVCNQIGIPYYAVNFEKEYWDKVFTYFLDEYKKGRTPNPDVMCNKEIKFKAFLDHAMNLGADYVATGHYARIHRHEDGHVEMLRGVDNNKDQTYFLNQLSQQQLSKVMFPIGDIEKSEVRRIAEEQGLVTAKKKDSTGICFIGEKNFKTFLSQYLPAQPGDMITLDGKKMGKHSGLMYYTIGQRHGLGIGGDGDPWFVVGKNLKDNVLYVEQGFHHDALYSDYLIASDYSFVNPEDNDLDQGFECTAKFRYRQKDTKVFVKRENDHALRVTFAEPVRAITPGQAVVFYQGDVCLGGATIDDVFKNEGQLNYVV
>NC_002745.2|WP_000409157.1|1654447_1655590_-|cysteine-desulfurase
MEIYADYAATTPVKPEVVDAMMMIYNSHYGNPSSIHAKGRDARKYLDESRRQIAQLLGADTHEIIFTSGATESNNTAIKGIVKANEQLGNHIITSKIEHHSVLHVFEQLEREGFDVTYLDVDDTGAIDLDQLEETITDKTILVSIMFVNNEVGTVQQIYDIQDIIAETNAYFHVDAVQAIGHLDVKFDEFEIDAMSITAHKFGGPKGVGALLVKDHVTLDYPQLGGEQELKRRAGTENLAQIVGMAKALQLAEKNRDDNNIHLMNLKEQFLVKLQERAIPFELNGSMTDATGHIVNLYFPFVEVEMMLTLLDMAQIYVSSGSACTAGSTQPSHVLDAMFEDEERSNHSIRFSFNELTTENEINAIVAEIHKIYFKFKEES
>NC_002745.2|WP_000985878.1|1655901_1656915_+|LLM-class-flavin-dependent-oxidoreductase
MAIKYSALNLVPIREGDDERTAINDMVKLAQHLDELSYERYWIAEHHNAPNLVSSATALLIQHTLEHTKHIRVGSGGIMLPNHAPLIVAEQFGTMATLFPNRVDLGLGRAPGTDMMTASALRRDQHDGVYKFPEEVSLLQQYFGPAHQQAYVRAYPAVGKNVPLYILGSSTDSAHLAARKGLPYVFAGHFAPQQMKEAIEIYKTLFEPSDVLDEPYVIVCLNTIVAENDDEAQYLASSMAQVMVSITRGRMQPVQPPTHDLQNILTPREYAMAMERQKISLIGSENTVQQKIQDFMETYGEVNEIMAISYIYDKDMQLDSYRRFKNVINQINEKNTL
>NC_002745.2|WP_000009238.1|1657151_1657298_-|hypothetical-protein
MSFMDKAKDAVEKFKNSDNEQVKNVKDKINEYTGSNNEEKKENEDKEK
>NC_002745.2|WP_000752909.1|1657337_1657520_-|CsbD-family-protein
MADESKFDQFKGNVKETVGNVTDNKELEKEGQQDKATGKAKEVVENAKNKITDAIDKLKK
>NC_002745.2|WP_000704122.1|1657619_1658042_-|Rrf2-family-transcriptional-regulator
MKISTKGRYGLTLMISLAKKEGQGCISLKSIAEENNLSDLYLEQLVGPLRNAGLIRSVRGAKGGYQLRVPAEEISAGDIIRLLEGPITFVESIESEPPAQKQLWIRMRDAVRDVLDNTTLKYLAEYVDTSEDLDGYMFYI
>NC_002745.2|WP_000102729.1|1658126_1659401_+|replication-associated-recombination-protein-A
MSTEPLASRMRPKNIDEIISQQHLVGPKGIIRRMVDTKKLTSMIFYGPPGIGKTSIAKAISGSTQYKFRQLNAVTNTKKDMQLVVEEAKMSGQVILLLDEIHRLDKAKQDFLLPHLENGKIVLIGATTSNPYHAINPAIRSRAQIFELYPLNDEDVRQALTRAIEDDENGLKTYQPKIDEDAMTYFSTQSQGDVRSALNALELAVLSADNDKDGYRHVTLQDAKDCLQKGAFVSDKDGDMHYDVMSAFQKSIRGSDVNAALHYLARLIEAGDLPTIVRRLLVISYEDIGLASPNAGQRTLAAIESAERLGLPEARIPLSQAVIELCLSPKSNSAMSAIDSALSDIRNGHVGQIPNHLKDGHYQGAKDLGRSIGYKYPHQYVNGYVSQQYLPDKLKNKIYYEPKTTSKSEQQLKEIYNNLLKQRP
>NC_002745.2|WP_000682646.1|1659561_1660335_-|tRNA-threonylcarbamoyladenosine-dehydratase
MKHQFSRNELAIGQQGLDLLKQQTVVILGVGGVGSFAAEALARTNIGHIILIDKDDVDITNVNRQLHALTTTVGQSKVSLMEERIKLINPDCKVTPLHMFYTEETYEEIFDNYDIDYFVDASDTIMYKVHLMKECLDRGIKVISSMGAANKTDPTRFTISDISKTHTDPMAKIIRQKLKKLGIRKGIPVVFSDESPIVIREDVKDIVGDKNAINRKGQMPPSSNAFVPSVVGLICASYVVNDVLKDIPVRRIKDKGQ
>NC_002745.2|WP_001790559.1|1660334_1660463_-|hypothetical-protein
MGFIAFNKCFLVEFWENNQSDNAKYKILSYYVLMYKSVKEVK
>NC_002745.2|WP_000044799.1|1660795_1662562_-|aspartate--tRNA-ligase
MSKRTTYCGLVTEAFLGQEITLKGWVNNRRDLGGLIFVDLRDREGIVQVVFNPAFSEEALKIAETVRSEYVVEVQGTVTKRDPETVNPKIKTGQVEVQVTNIKVINKSETPPFSINEENVNVDENIRLKYRYLDLRRQELAQTFKMRHQITRSIRQYLDDEGFFDIETPVLTKSTPEGARDYLVPSRVHDGEFYALPQSPQLFKQLLMISGFDKYYQIVKCFRDEDLRADRQPEFTQVDIEMSFVDQEDVMQMGEEMLKKVVKEVKGVEINGAFPRMTYKEAMRRYGSDKPDTRFEMELIDVSQLGRDMDFKVFKDTVENDGEIKAIVAKGAAEQYTRKDMDALTEFVNIYGAKGLAWVKVVEDGLTGPIGRFFETENVETLLTLTGAEAGDLVMFVADKPNVVAQSLGALRVKLAKELGLIDETKLNFLWVTDWPLLEYDEDAKRYVAAHHPFTSPKEADIAKLGTAPEEAEANAYDIVLNGYELGGGSIRIHDGELQEKMFEVLGFTKEQAQEQFGFLLDAFKYGAPPHGGIALGLDRLVMLLTNRTNLRDTIAFPKTASATCLLTNAPGEVSDKQLEELSLRIRH

Crispr_ID: NC_002745_8

• CRISPR_ID: NC_002745_8
• CRISPR_location: 2054612-2054693
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers
• Cas_protein_info: DEDDh

Consensus repeat of NC_002745_8

Consensus_repeat	Method
GGCCCCCACCCCAACTTACATTGT	CRISPRCasFinder

spacers of NC_002745_8

>8.1|2054636|34|NC_002745|CRISPRCasFinder
TTGTAGAATTTCTTTTCGAAATTCTCTGTGTTGG

CRISPR arrays and Neighbor proteins around NC_002745_8

CRISPR arrays

The CRISPR arrays of NC_002745_8

>merge|NC_002745|8|2054612-2054693|CRISPRCasFinder
GGCCCCCACCCCAACTTACATTGTTTGTAGAATTTCTTTTCGAAATTCTCTGTGTTGGGGCCCCCACCCCAACTTGCATTGT

>NC_002745|8|7|2054612-2054693|CRISPRCasFinder
GGCCCCCACCCCAACTTACATTGT	TTGTAGAATTTCTTTTCGAAATTCTCTGTGTTGG
GGCCCCCACCCCAACTTGCATTGT

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_002745.2|WP_000791411.1|2051676_2052732_-|bi-component-leukocidin-LukGH-subunit-H	unknown	unknown	gnl|CDD|369625
NC_002745.2|WP_001293088.1|2061934_2062504_-|terminase-small-subunit	unknown	unknown	gnl|CDD|226251
NC_002745.2|WP_001035599.1|2061075_2061780_+|toxic-shock-syndrome-toxin-TSST-1	unknown	unknown	gnl|CDD|171853
NC_002745.2|WP_000694772.1|2046901_2047084_+|hypothetical-protein	unknown	unknown	unknown
NC_002745.2|WP_000591749.1|2046356_2046698_+|hypothetical-protein	unknown	unknown	unknown
NC_002745.2|WP_000358774.1|2062500_2062842_-|hypothetical-protein	unknown	unknown	unknown
NC_002745.2|WP_000846280.1|2063658_2064237_-|hypothetical-protein	unknown	unknown	unknown
NC_002745.2|WP_000746599.1|2057158_2057881_+|staphylococcal-enterotoxin-type-L	unknown	unknown	gnl|CDD|280949
NC_002745.2|WP_000448770.1|2063422_2063641_-|hypothetical-protein	unknown	unknown	gnl|CDD|374753
NC_002745.2|WP_000278088.1|2058049_2058850_-|staphylococcal-enterotoxin-type-C3	unknown	unknown	gnl|CDD|280949
NC_002745.2|WP_001031454.1|2044689_2045403_+|helix-turn-helix-transcriptional-regulator	unknown	unknown	gnl|CDD|225484
NC_002745.2|WP_000857180.1|2048482_2049520_+|site-specific-integrase	unknown	unknown	gnl|CDD|271189
NC_002745.2|WP_001558608.1|2047183_2048167_+|glycosyltransferase-family-2-protein	unknown	unknown	gnl|CDD|366154
NC_002745.2|WP_000771368.1|2062844_2063372_-|spore-coat-protein	unknown	unknown	gnl|CDD|227864
NC_002745.2|WP_000427213.1|2048177_2048420_+|hypothetical-protein	unknown	unknown	unknown
NC_002745.2|WP_000206625.1|2053167_2054391_+|ArgE/DapE-family-deacylase	unknown	unknown	gnl|CDD|181490
NC_002745.2|WP_000595392.1|2050638_2051655_-|bi-component-leukocidin-LukGH-subunit-G	unknown	unknown	gnl|CDD|369625
NC_002745.2|WP_001035616.1|2059636_2060197_+|DUF4888-domain-containing-protein	unknown	unknown	gnl|CDD|294014
NC_002745.2|WP_000759682.1|2045418_2046351_+|ATP-dependent-helicase	DEDDh	cd06127_DEDDh_CAS-I	gnl|CDD|235735
NC_002745.2|WP_001045079.1|2054834_2056142_+|TrkH-family-potassium-uptake-protein	unknown	unknown	gnl|CDD|273349

HMMScan for Signature genes

Protein	Cas_name	Cas_description	E-value	Identity	Coverage
NC_002745.2|WP_000759682.1|2045418_2046351_+|ATP-dependent-helicase	DEDDh	cd06127_DEDDh_CAS-I	4.9e-23	76.7	0.0

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_002745.2|WP_000791411.1|2051676_2052732_-|bi-component-leukocidin-LukGH-subunit-H	gnl|CDD|369625	pfam07968, Leukocidin, Leukocidin/Hemolysin toxin family.	1.84035e-77
NC_002745.2|WP_001293088.1|2061934_2062504_-|terminase-small-subunit	gnl|CDD|226251	COG3728, XtmA, Phage terminase, small subunit [DNA replication, recombination, and repair].	4.68659e-70
NC_002745.2|WP_001035599.1|2061075_2061780_+|toxic-shock-syndrome-toxin-TSST-1	gnl|CDD|171853	PRK13038, PRK13038, superantigen-like protein; Reviewed.	1.96896e-09
NC_002745.2|WP_000278088.1|2058049_2058850_-|staphylococcal-enterotoxin-type-C3	gnl|CDD|280949	pfam02876, Stap_Strp_tox_C, Staphylococcal/Streptococcal toxin, beta-grasp domain.	1.74895e-25
NC_002745.2|WP_000746599.1|2057158_2057881_+|staphylococcal-enterotoxin-type-L	gnl|CDD|280949	pfam02876, Stap_Strp_tox_C, Staphylococcal/Streptococcal toxin, beta-grasp domain.	6.68431e-31
NC_002745.2|WP_000448770.1|2063422_2063641_-|hypothetical-protein	gnl|CDD|374753	pfam16722, SAPIS-gp6, Pathogenicity island protein gp6 in Staphylococcus. SAPIS-gp6 is a family of proteins produced from the pathogenicity island SAPI1 in pathogenic Staphylococcus aureus. This is a mobile genetic element that carries genes for several superantigen toxins. SAPIS-gp6 is a dimeric protein produced from the pathogenicity island with a helix-loop-helix motif similar to that of bacteriophage scaffolding proteins. It is thought to determine the size of the capsids of distribution of the SAPI1 genome as it acts as an internal scaffolding protein during capsid size determination.	1.38272e-18
NC_002745.2|WP_001031454.1|2044689_2045403_+|helix-turn-helix-transcriptional-regulator	gnl|CDD|225484	COG2932, COG2932, Predicted transcriptional regulator [Transcription].	5.17989e-24
NC_002745.2|WP_000206625.1|2053167_2054391_+|ArgE/DapE-family-deacylase	gnl|CDD|181490	PRK08588, PRK08588, succinyl-diaminopimelate desuccinylase; Reviewed.	0
NC_002745.2|WP_001558608.1|2047183_2048167_+|glycosyltransferase-family-2-protein	gnl|CDD|366154	pfam00535, Glycos_transf_2, Glycosyl transferase family 2. Diverse family, transferring sugar from UDP-glucose, UDP-N-acetyl- galactosamine, GDP-mannose or CDP-abequose, to a range of substrates including cellulose, dolichol phosphate and teichoic acids.	3.06668e-26
NC_002745.2|WP_000771368.1|2062844_2063372_-|spore-coat-protein	gnl|CDD|227864	COG5577, COG5577, Spore coat protein [Cell envelope biogenesis, outer membrane].	5.42048e-39
NC_002745.2|WP_000857180.1|2048482_2049520_+|site-specific-integrase	gnl|CDD|271189	cd01189, INT_ICEBs1_C_like, C-terminal catalytic domain of integrases from bacterial phages and conjugate transposons. This family of tyrosine based site-specific integrases is has origins in bacterial phages and conjugate transposons. One member is the integrase from Bacillus subtilis conjugative transposon ICEBs1. ICEBs1 can be excised and transfered to various recipients in response to DNA damage or high concentrations of potential mating partners. The family belongs to the superfamily of DNA breaking-rejoining enzymes, which share the same fold in their catalytic domain and the overall reaction mechanism. The catalytic domain contains six conserved active site residues. Their overall reaction mechanism involves cleavage of a single strand of a DNA duplex by nucleophilic attack of a conserved tyrosine to give a 3' phosphotyrosyl protein-DNA adduct. In the second rejoining step, a terminal 5' hydroxyl attacks the covalent adduct to release the enzyme and generate duplex DNA.	5.76637e-25
NC_002745.2|WP_000759682.1|2045418_2046351_+|ATP-dependent-helicase	gnl|CDD|235735	PRK06195, PRK06195, DNA polymerase III subunit epsilon; Validated.	1.68456e-42
NC_002745.2|WP_000595392.1|2050638_2051655_-|bi-component-leukocidin-LukGH-subunit-G	gnl|CDD|369625	pfam07968, Leukocidin, Leukocidin/Hemolysin toxin family.	1.05827e-99
NC_002745.2|WP_001035616.1|2059636_2060197_+|DUF4888-domain-containing-protein	gnl|CDD|294014	cd15783, SA1633_like, Uncharacterized protein family conserved in Staphylococci. Some proteins in this family have been described as putative beta-lactamases. They are structurally similar to the C-terminal beta-grasp domains of Staphylococcal and Streptococcal superantigens.	1.47157e-43
NC_002745.2|WP_001045079.1|2054834_2056142_+|TrkH-family-potassium-uptake-protein	gnl|CDD|273349	TIGR00933, Trk_system_potassium_uptake_protein_trkH., potassium uptake protein, TrkH family. The proteins of the Trk family are derived from Gram-negative and Gram-positive bacteria, yeast and wheat. The proteins of E. coli K12 TrkH and TrkG as well as several yeast proteins have been functionally characterized.The E. coli TrkH and TrkG proteins are complexed to two peripheral membrane proteins, TrkA, an NAD-binding protein, and TrkE, an ATP-binding protein. This complex forms the potassium uptake system. [Transport and binding proteins, Cations and iron carrying compounds].	7.96864e-82

Protein sequences

>NC_002745.2|WP_000206625.1|2053167_2054391_+|ArgE/DapE-family-deacylase
MTTFSEKEKIQLLADIVELQTENNNEIDVCNYLKDLFDKYDIKSEILKVNEHRANIVAEIGNGSPILALSGHMDVVDAGNQDNWTYPPFQLTEKAGKLYGRGTTDMKGGLMALVITLIELKEQNQLPQGTIRLLATAGEEKEQEGAKLLADKGYLDDVDGLIIAEPTGSGIYYAHKGSMSCKVTATGKAVHSSVPFIGDNAIDTLLEFYNQFKEKYSELKKHDTKHELDVAPMFKSLIGKEISEEDANYASGLTAVCSIINGGKQFNSVPDEASLEFNVRPVPEYDNDFIESFFQNIINDVDSNKLSLDIPSNHRPVTSDKNSKLITTIKDVASSYVEQDEIFVSALVGATDASSFLGDNKDNVDLAIFGPGNPLMAHQIDEYIEKDMYLKYIDIFKEASIQYLKEK
>NC_002745.2|WP_000791411.1|2051676_2052732_-|bi-component-leukocidin-LukGH-subunit-H
MKNKKRVLIASSLSCAILLLSAATTQANSAHKDSQDQNKKEHVDKSQQKDKRNVTNKDKNSTVPDDIGKNGKITKRTETVYDEKTNILQNLQFDFIDDPTYDKNVLLVKKQGSIHSNLKFESHKEEKNSNWLKYPSEYHVDFQVKRNRKTEILDQLPKNKISTAKVDSTFSYSSGGKFDSTKGIGRTSSNSYSKTISYNQQNYDTIASGKNNNWHVHWSVIANDLKYGGEVKNRNDELLFYRNTRIATVENPELSFASKYRYPALVRSGFNPEFLTYLSNEKSNEKTQFEVTYTRNQDILKNRPGIHYAPPILEKNKDGQRLIVTYEVDWKNKTVKVVDKYSDDNKPYKEG
>NC_002745.2|WP_000595392.1|2050638_2051655_-|bi-component-leukocidin-LukGH-subunit-G
MIKQLYKNITICSLAISTALTVFPATSYAKINSEIKAVSEKNLDGDTKMYTRTATTSDSQKNITQSLQFNFLTEPNYDKETVFIKAKGTIGSGLRILDPNGYWNSTLRWPGSYSVSIQNVDDNNNTNVTDFAPKNQDESREVKYTYGYKTGGDFSINRGGLTGNITKESNYSETISYQQPSYRTLLDQSTSHKGVGWKVEAHLINNMGHDHTRQLTNDSDNRTKSEIFSLTRNGNLWAKDNFTPKDKMPVTVSEGFNPEFLAVMSHDKKDKGKSQFVVHYKRSMDEFKIDWNRHGFWGYWSGENHVDKKEEKLSALYEVDWKTHDVKFVKVLNDNEKK
>NC_002745.2|WP_000857180.1|2048482_2049520_+|site-specific-integrase
MKTRCYDGKKWQYEFKHEGKRYRKKGFRTKREANSAGLDKLNELRSGFNIDNYITLEEYFENWIKTYKQPVVKENTYRHYRNALQHIQKHKIGKMELSKINRQVYQKFINDHSKEHAKETIRKTNGAIRSALDDALYDGLIFKNPAYKVNYKAGKPTKSEQEKFISVTEYEILKDHVRKKRTRSSLALFIMICTGCRVSGARNIKIEHINQVKNTIFIDERKTDTSPRYISIAKSDMKHIMDVISTFAISYDGYIFKEAGSIINLQAINNALKSACRVNNIPIITSHALRHTHCSYLLAKGVSIHYISKRLGHKNIAITTSVYSHLLEEKFNEEDKKTTKILESM
>NC_002745.2|WP_000427213.1|2048177_2048420_+|hypothetical-protein
MENFNYNNIKKLVLENVDIDKVKEVYKDYELLNYTIKNQTLYMNDYEVAKVSEKHLNENINNLRGTVNLDEKCILSLTYL
>NC_002745.2|WP_001558608.1|2047183_2048167_+|glycosyltransferase-family-2-protein
MKKVSVIMPTFNNGEKLHRTISSVLNQTMKSTDYELIIIDDHSNDNGETLNVIKKYKGLVRFKQLKKNSGNASVPRNTGLKMSKAEYVFFLDSDDLLHERALEDLYNYGKENNSDLIIGKYGVEGKGRSVPKAIFEKGNVAKADIIDNSIFYALSVLKMFKKSVIDKNKIKFKTFSKTAEDQLFTIEFLMNSKNYSIKTDYEYYIVVNDFESSNHLSVNKSTGNQYFATINEIYKAIYKSPIYKNQEKRHQLAGKYTTRLLRHGQKKNFANSKMKYEDKIEWLNNFSKTINKVPRDSDKYVTQIFNLKLEAIRQNDLLAVMIADKLL
>NC_002745.2|WP_000694772.1|2046901_2047084_+|hypothetical-protein
MKIKNCKIKKETIVYEVLTSGNQPFTYELPKDLSSHNARKYLEFISQKLDGDKLTKEDSL
>NC_002745.2|WP_000591749.1|2046356_2046698_+|hypothetical-protein
MIKKIFTKKHVFLVIEDENHNHSDAVFGKSILLSIYVGVNKKTNSKSGKFIYLDRSKRIVRQSDITKIESANENDVDFYNLLKKEKEIVYSKNIVDKYNLANYIIYYEVSTKE
>NC_002745.2|WP_000759682.1|2045418_2046351_+|ATP-dependent-helicase
MKKYDIAVLDFETMNEHMNSPCEVAVSLIKDLSIVKVYSSYINPPNNRYNLKNAKIHKIPEDVILKAPKYPDIYQEILYLLKESHLIIAHNALFDISVLKNTNNYYDLPVPNFMYVDSINIFRSFHAISSFKLENLCSLYDIDKEKLHSAKFDVLALSKMLISLAKNNQHYSVLKLIHYMPKQYIRFSKYSNSPTKLFDSGFQKIHMKISEINKIEVESVIPILKDKNVVFTGNFDTEKQDLMILTRKKGAYIRSDVTAKTDILVEGVQDDKYKDVNGLVSKQRKAREYVGNGAKIQFLNEEDLINLIKE
>NC_002745.2|WP_001031454.1|2044689_2045403_+|helix-turn-helix-transcriptional-regulator
MNKERNIIIAKNIRKFLNDSNMSQKKLAELINIKPSTLSDYLNLRSNPSHGVIQRIADVFEVGKSDIDTTYKDDNDITSIYNKLTPPRQENVLNYANEQLEEQNSKGDNVVDINSYKQEKTPVNVNGCVSAGVGERLHDETLFTEMVKGPIPTHDLALKVNGDSMEPMFKDGEIIFVEKTHNIKNGQIGIFIIEEEAYVKKVFVEDDRLTLVSLNKDYDDLHFYRNESVRLIGKVIL
>NC_002745.2|WP_001045079.1|2054834_2056142_+|TrkH-family-potassium-uptake-protein
MNKVHKPLYFYLMLFFSTTIIGALLLYLPFTGKKPISFLDALFIASSAFTVTGLSPVDIGSQFNILGEIVILLLIQIGGLGIVTVTLLTLVFLNRKISMKNRFLIMVTWNIDEPGGVIKLIKHLAIYSLVTELIGMICLCLSFIPKFGIGKGLFLSLFTSVSAFNNAGFALFKNNLIDYSSDPIVIITISILIIFGGIGHFVVIDFINCKKLSKLSLHSKLVLTTTSILIIIGAITFFLLEQFNTMQHMGLVEKIGNSFFQSVTTRTAGFNSIDIASINKSTALMLMLLMFIGGAPLSAAGGIKITTFAVAFIFVLNYIRKENNVSVFNKEISDKHIKLSIVTINISFLFISIITFILSIINPNISLIKLLFEVVSAFGTVGLSMNLTTEYHGITKIIIIFVMLCGKVGLLTLLRTFIPPKSPKNYRYTKGQIYL
>NC_002745.2|WP_000746599.1|2057158_2057881_+|staphylococcal-enterotoxin-type-L
MKKRLLFVIVITLFIFSSNHTVLSNGDVGPGNLRNFYTKYEYVNLKNVKDKNSPESHRLEYSYKNDTLYAEFDNEYITSDLKGKNVDVFGISYKYGSNSRTIYGGVTKAENNKLDSPRIIPINLIINGKHQTVTTKSVSTDKKMVTAQEIDVKLRKYLQDEFNIYGHNDTGKGKEYGTSSKFYSGFDKGSVVFHMNDGSNFSYDLFYTGYGLPESFLKIYKDNKTVDSTQFHLDVEISKR
>NC_002745.2|WP_000278088.1|2058049_2058850_-|staphylococcal-enterotoxin-type-C3
MYKRLFISRVILIFALILVISTPNVLAESQPDPMPDDLHKSSEFTGTMGNMKYLYDDHYVSATKVKSVDKFLAHDLIYNISDKKLKNYDKVKTELLNEDLAKKYKDEVVDVYGSNYYVNCYFSSKDNVGKVTGGKTCMYGGITKHEGNHFDNGNLQNVLVRVYENKRNTISFEVQTDKKSVTAQELDIKARNFLINKKNLYEFNSSPYETGYIKFIENNGNTFWYDMMPAPGDKFDQSKYLMMYNDNKTVDSKSVKIEVHLTTKNG
>NC_002745.2|WP_001035616.1|2059636_2060197_+|DUF4888-domain-containing-protein
MNKKLLTKTLIASALVLTTVGSGFHSSSNYNGINNVAKAEQTTDNALWKNVRDALKDANIIDKTDNENVKVTYKIENGGENTIEGTANLENISTSNNPKINPQNVTKINITRKNSNYPNIDANNTWKKLTEKLKEKNIVNNGDNVSILSTDPKDETVFGKVGEDKSNVSNRYINPKDINEIQITKK
>NC_002745.2|WP_001035599.1|2061075_2061780_+|toxic-shock-syndrome-toxin-TSST-1
MNKKLLMNFFIVSPLLLATIATDFTPVPLSSNQIIKTAKASTNDNIKDLLDWYSSGSDTFTNSEVLDNSLGSMRIKNTDGSISLIIFPSPYYSPAFTKGEKVDLNTKRTKKSQHTSEGTYIHFQISGVTNTEKLPTPIELPLKVKVHGKDSPLKYWPKFDKKQLAISTLDFEIRHQLTQIHGLYRSSDKTGGYWKITMNDGSTYQSDLSKKFEYNTEKPPINIDEIKTIEAEIN
>NC_002745.2|WP_001293088.1|2061934_2062504_-|terminase-small-subunit
MSELTAKQARFVNEYIRTLNVTQSAIKAGYSANSAHVTGCRLLKKPHIKQYIQEQKDKVIDENVLTAKELLHVLTNAAVGDETETKEVVVKRGEYKENPQSGKVQLVYNEHVELVEVPIKPSDRLKARDMLGKYHKLFTDKHDINGNVPIFINIGEWDGDDEDLDKTVQEVSNANPNHTVIVDDIPLED
>NC_002745.2|WP_000358774.1|2062500_2062842_-|hypothetical-protein
MDKKQIKDFVCDYHKRTISDVLIDDEINTDEFFSIGDENSNEWMADDNIDDHIVKNHLEMIVDQVANDKEFYIFDSLIQGRSFKDISNVLECSEQSVRLWYETLLDKIVEVIE
>NC_002745.2|WP_000771368.1|2062844_2063372_-|spore-coat-protein
MKLLKTKNCLYYRNGDNKLSEYQLLTQFNPAFINKKIKMCEFQIESMYHMSASTTTCDEIMGVVSVSYPIEKLVIKIIETKAGLQNYKNRSINNMALLKKVLNHYTEKEQKQVVKYMRSNGRYKPYNVIERLQVDLYQASIKQRSERQKQRNTAIENSKIARVNAYHQSSYVKVV
>NC_002745.2|WP_000448770.1|2063422_2063641_-|hypothetical-protein
METKYELNNTKKVANAFGLNEADTNLLINAVDLDIKNNMQEISSELQQSEQSKQKQYGTTLQNLAKQNRIIK
>NC_002745.2|WP_000846280.1|2063658_2064237_-|hypothetical-protein
MKTESYFKEYNQFVIDQQKAIQELEQERNALESKIKIDKSTYKQLIMDGQDDKADNLYQATDADEKKLKALNKRLETKKSVSKEVKYQKTIELLKHQSELSSLYESEKQSALGKLKKVVDAYNEIIDEIEDINDRYEDEHQQYASIYSQEQLYDDKEAREALNGYFRENIFTSYINGNDLPYEHNNKLFLKR

Crispr_ID: NC_002745_9

• CRISPR_ID: NC_002745_9
• CRISPR_location: 2070257-2070345
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NC_002745_9

Consensus_repeat	Method
GTTTTTGACTGACTTCTCAATCA	CRISPRCasFinder

spacers of NC_002745_9

>9.1|2070280|43|NC_002745|CRISPRCasFinder
ATTTATAACTTTATTATACATAATCGTTTTTCTTTTGCAATAG

CRISPR arrays and Neighbor proteins around NC_002745_9

CRISPR arrays

The CRISPR arrays of NC_002745_9

>merge|NC_002745|9|2070257-2070345|CRISPRCasFinder
GTTTTTGACTGACTTCTCAATCAATTTATAACTTTATTATACATAATCGTTTTTCTTTTGCAATAGTTTTTCGACTGACTTCTCAATCA

>NC_002745|9|8|2070257-2070345|CRISPRCasFinder
GTTTTTGACTGACTTCTCAATCA	ATTTATAACTTTATTATACATAATCGTTTTTCTTTTGCAATAG
TTTTTCGACTGACTTCTCAATCA

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_002745.2|WP_001549197.1|2079075_2079210_-|delta-lysin-family-phenol-soluble-modulin	unknown	unknown	gnl|CDD|173213
NC_002745.2|WP_000917289.1|2074032_2074317_-|co-chaperone-GroES	unknown	unknown	gnl|CDD|178988
NC_002745.2|WP_001078344.1|2069024_2069351_-|DUF1474-family-protein	unknown	unknown	gnl|CDD|369323
NC_002745.2|WP_000240642.1|2072340_2073957_-|chaperonin-GroEL	unknown	unknown	gnl|CDD|234573
NC_002745.2|WP_000620857.1|2070411_2071086_+|helix-turn-helix-transcriptional-regulator	unknown	unknown	gnl|CDD|379188
NC_002745.2|WP_000153640.1|2070020_2070239_-|helix-turn-helix-transcriptional-regulator	unknown	unknown	gnl|CDD|197775
NC_002745.2|WP_000867951.1|2077690_2078476_+|carbon-nitrogen-family-hydrolase	unknown	unknown	gnl|CDD|143607
NC_002745.2|WP_001047698.1|2065039_2065681_-|hypothetical-protein	unknown	unknown	gnl|CDD|374630
NC_002745.2|WP_001058495.1|2069353_2069563_-|hypothetical-protein	unknown	unknown	unknown
NC_002745.2|WP_000179343.1|2071099_2072272_+|tyrosine-type-recombinase/integrase	unknown	unknown	gnl|CDD|271189
NC_002745.2|WP_000447473.1|2066367_2068077_-|DUF927-domain-containing-protein	unknown	unknown	gnl|CDD|227806
NC_002745.2|WP_001105696.1|2079445_2080009_+|accessory-gene-regulator-ArgB-like-protein	unknown	unknown	gnl|CDD|226899
NC_002745.2|WP_000784885.1|2069555_2069702_-|hypothetical-protein	unknown	unknown	unknown
NC_002745.2|WP_000356942.1|2065677_2066058_-|hypothetical-protein	unknown	unknown	unknown
NC_002745.2|WP_001002689.1|2068090_2068960_-|primase-C-terminal-domain-containing-protein	unknown	unknown	gnl|CDD|214926
NC_002745.2|WP_000481967.1|2069698_2070016_-|helix-turn-helix-domain-containing-protein	unknown	unknown	gnl|CDD|200128
NC_002745.2|WP_000120296.1|2075259_2076507_-|hypothetical-protein	unknown	unknown	gnl|CDD|236768
NC_002745.2|WP_001190615.1|2064248_2064590_-|hypothetical-protein	unknown	unknown	unknown
NC_002745.2|WP_000197635.1|2074491_2075235_+|CPBP-family-intramembrane-metalloprotease	unknown	unknown	gnl|CDD|376806
NC_002745.2|WP_000522381.1|2076703_2077330_+|nitroreductase-family-protein	unknown	unknown	gnl|CDD|226090

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_002745.2|WP_000917289.1|2074032_2074317_-|co-chaperone-GroES	gnl|CDD|178988	PRK00364, groES, co-chaperonin GroES; Reviewed.	5.94304e-45
NC_002745.2|WP_000240642.1|2072340_2073957_-|chaperonin-GroEL	gnl|CDD|234573	PRK00013, groEL, chaperonin GroEL; Reviewed.	0
NC_002745.2|WP_000620857.1|2070411_2071086_+|helix-turn-helix-transcriptional-regulator	gnl|CDD|379188	pfam13443, HTH_26, Cro/C1-type HTH DNA-binding domain. This is a helix-turn-helix domain that probably binds to DNA.	1.58614e-10
NC_002745.2|WP_000153640.1|2070020_2070239_-|helix-turn-helix-transcriptional-regulator	gnl|CDD|197775	smart00530, HTH_XRE, Helix-turn-helix XRE-family like proteins.	9.85461e-11
NC_002745.2|WP_000867951.1|2077690_2078476_+|carbon-nitrogen-family-hydrolase	gnl|CDD|143607	cd07583, nitrilase_5, Uncharacterized subgroup of the nitrilase superfamily (putative class 13 nitrilases). The nitrilase superfamily is comprised of nitrile- or amide-hydrolyzing enzymes and amide-condensing enzymes, which depend on a Glu-Lys-Cys catalytic triad. This superfamily has been classified in the literature based on global and structure based sequence analysis into thirteen different enzyme classes (referred to as 1-13). Class 13 represents proteins that at the time were difficult to place in a distinct similarity group; this subgroup represents either a new class or one that was included previously in class 13. Members of this superfamily generally form homomeric complexes, the basic building block of which is a homodimer.	5.69545e-126
NC_002745.2|WP_001047698.1|2065039_2065681_-|hypothetical-protein	gnl|CDD|374630	pfam16560, SAPI, Putative mobile pathogenicity island. SAPI is a family of putative Gram-positive mobile pathogenicity island proteins. SAPIs are responsible for many superantigen-related diseases in humans as they carry two or more superantigens.	3.70035e-117
NC_002745.2|WP_000197635.1|2074491_2075235_+|CPBP-family-intramembrane-metalloprotease	gnl|CDD|376806	pfam02517, Abi, CAAX protease self-immunity. Members of this family are probably proteases (after a isoprenyl group is attached to the Cys residue in the C-terminal CAAX motif of a protein to attach it to the membrane, the AAX tripeptide being removed by one of the CAAX prenyl proteases). The family contains the CAAX prenyl protease. The proteins contain a highly conserved Glu-Glu motif at the amino end of the alignment. The alignment also contains two histidine residues that may be involved in zinc binding. While they are involved in membrane anchoring of proteins in eukaryotes, little is known about their function in prokaryotes. In some known bacteriocin loci, Abi genes have been found downstream of bacteriocin structural genes where they are probably involved in self-immunity. Investigation of the bacteriocin-like loci in the Gram positive bacteria locus from Lactobacillus sakei 23K confirmed that the bacteriocin-like genes (sak23Kalphabeta) exhibited antimicrobial activity when expressed in a heterologous host and that the associated Abi gene (sak23Ki) conferred immunity against the cognate bacteriocin. Interestingly, the immunity genes from three similar systems conferred a high degree of cross-immunity against each other's bacteriocins, suggesting the recognition of a common receptor. Site-directed mutagenesis demonstrated that the conserved motifs constituting the putative proteolytic active site of the Abi proteins are essential for the immunity function of Sak23Ki - thus a new concept in self-immunity.	1.67124e-11
NC_002745.2|WP_000179343.1|2071099_2072272_+|tyrosine-type-recombinase/integrase	gnl|CDD|271189	cd01189, INT_ICEBs1_C_like, C-terminal catalytic domain of integrases from bacterial phages and conjugate transposons. This family of tyrosine based site-specific integrases is has origins in bacterial phages and conjugate transposons. One member is the integrase from Bacillus subtilis conjugative transposon ICEBs1. ICEBs1 can be excised and transfered to various recipients in response to DNA damage or high concentrations of potential mating partners. The family belongs to the superfamily of DNA breaking-rejoining enzymes, which share the same fold in their catalytic domain and the overall reaction mechanism. The catalytic domain contains six conserved active site residues. Their overall reaction mechanism involves cleavage of a single strand of a DNA duplex by nucleophilic attack of a conserved tyrosine to give a 3' phosphotyrosyl protein-DNA adduct. In the second rejoining step, a terminal 5' hydroxyl attacks the covalent adduct to release the enzyme and generate duplex DNA.	1.67501e-47
NC_002745.2|WP_000447473.1|2066367_2068077_-|DUF927-domain-containing-protein	gnl|CDD|227806	COG5519, COG5519, Superfamily II helicase and inactivated derivatives [DNA replication, recombination, and repair].	0
NC_002745.2|WP_001105696.1|2079445_2080009_+|accessory-gene-regulator-ArgB-like-protein	gnl|CDD|226899	COG4512, AgrB, Membrane protein putatively involved in post-translational modification of the autoinducing quorum-sensing peptide [Posttranslational modification, protein turnover, chaperones / Signal transduction mechanisms / Transcription].	6.65966e-71
NC_002745.2|WP_001549197.1|2079075_2079210_-|delta-lysin-family-phenol-soluble-modulin	gnl|CDD|173213	PRK14752, PRK14752, delta-lysin family phenol-soluble modulin.	8.25732e-15
NC_002745.2|WP_001002689.1|2068090_2068960_-|primase-C-terminal-domain-containing-protein	gnl|CDD|214926	smart00942, PriCT_1, Primase C terminal 1 (PriCT-1). This alpha helical domain is found at the C terminal of primases.	1.21323e-15
NC_002745.2|WP_000481967.1|2069698_2070016_-|helix-turn-helix-domain-containing-protein	gnl|CDD|200128	TIGR01764, Probable_excisionase, DNA binding domain, excisionase family. An excisionase, or Xis protein, is a small protein that binds and promotes excisive recombination; it is not enzymatically active. This model represents a number of putative excisionases and related proteins from temperate phage, plasmids, and transposons, as well as DNA binding domains of other proteins, such as a DNA modification methylase. This model identifies mostly small proteins and N-terminal regions of large proteins, but some proteins appear to have two copies. This domain appears similar, in both sequence and predicted secondary structure (PSIPRED) to the MerR family of transcriptional regulators (pfam00376). [Unknown function, General].	5.89089e-17
NC_002745.2|WP_000120296.1|2075259_2076507_-|hypothetical-protein	gnl|CDD|236768	PRK10819, PRK10819, transport protein TonB; Provisional.	8.13501e-10
NC_002745.2|WP_001078344.1|2069024_2069351_-|DUF1474-family-protein	gnl|CDD|369323	pfam07342, DUF1474, Protein of unknown function (DUF1474). This family consists of several bacterial proteins of around 100 residues in length. Members of this family seem to be found exclusively in Staphylococcus aureus. The function of this family is unknown.	1.179e-19
NC_002745.2|WP_000522381.1|2076703_2077330_+|nitroreductase-family-protein	gnl|CDD|226090	COG3560, FMR2, Predicted oxidoreductase related to nitroreductase [General function prediction only].	8.42197e-117

Protein sequences

>NC_002745.2|WP_000153640.1|2070020_2070239_-|helix-turn-helix-transcriptional-regulator
MTILANTRKFKEAMFLKGFNLSDLSRETGVGISYLSQIINGKKIPSPKLAKKMAEVLQVEVNELFEFEVKEA
>NC_002745.2|WP_000481967.1|2069698_2070016_-|helix-turn-helix-domain-containing-protein
MFNINIDEDEARELLEQAINARVDELAKEKYFMTYKELSNYLNLSKPTIEELLINNGMKYYMVGSTYRFKKSDVDEFMEQLTAHMNIQNNDFKQVNIKKLLEARQ
>NC_002745.2|WP_000784885.1|2069555_2069702_-|hypothetical-protein
MKMYLTYICLVSLLTILLLAISNMYVAFSVYAWLITLGCNLTGGLENE
>NC_002745.2|WP_001058495.1|2069353_2069563_-|hypothetical-protein
MNNEQKEVIEHVVYQLELSVVNNLESYEHTEYVNGIEVVSEISREKHLELIMKWCAQELKNNFQLEKGE
>NC_002745.2|WP_001078344.1|2069024_2069351_-|DUF1474-family-protein
MNREIKDLFSDLKLLKDSFEDLKDSNGWHFDELYPYEPNHVLNKDELIGEGFSYHERRIHNNQMFDLFHLYIEQFDNIIEKFYEIEKASSENFGEESDDAKNSIKVAE
>NC_002745.2|WP_001002689.1|2068090_2068960_-|primase-C-terminal-domain-containing-protein
MNEIKLEYDTHVSVVHYESLDSRSFKSFSKPEWSKLVNKLSVPIEANYKYARGVAVYGDIKDGANDHGETIKKHRNDVNVIYRDVIVLDYDEINDLKQLHEAISSVLSSVAWYWHTSFSHTTEQARIRLYIPLNERISADDYRKYTKVLANKIGHKVDEGSYQPSRCFALPVIQKGHIFIKRVNDCPIMNVDMLEQWSKEFEQSNASPNVIGYTRRDSEYWRELCFGTTEGNRNNALASLIGHLLRCHVNDYIVYSFALLWGQFACKPPMKEQEINATFQSILNKHYNN
>NC_002745.2|WP_000447473.1|2066367_2068077_-|DUF927-domain-containing-protein
METGKSDVLDKIEKINKKDSALQEIIPKGYEIEHHQCGVALYQLIPSKKEGEPDKKVFITNTIPQITERFEDIESNEVSFNMLFYDNKTPVNIAVSAEEISDSRQLLKLVNKKLDVTSSTSTKLVDYINVSKRYNPPLNVKVATRLGHVKGYFIYPYQEVMKDSNVKLFSNDKGFQKLIDSFRSKGTLQGYSKKVFAQIKDLPMVMVMLYASLGSVLLREFGLQPFIVEISGSTSTGKTFTLNLVSSVWGTSDLITTWSSTQNSIESMASFLNSFPMFKDDTRNTHPKFVTSTTYNFSSGESKSRSNINLTLNAKKEWRNILISTGESSIANMADEKAGVSARVVTLQDPPYPDNFDFTTLDKSFRENYGTLGLAFIKQYESKKDVYKNAFESYQRYFNQKGSNEIMQRLGRAFALLQVTGEVLNDIDGFEHDHFKIIEQAYDSMVKNNKTIDKPKQLLEELLQYLDANRNNIVGDGYDSVNYGDVKAVYKHDFLCIKNETVKNKLGHEMQTITGQWDKKGYLIKDKKRIQKQVKHKSQRHLGYAIKKEIIEELGFDFSISHNPYTESY
>NC_002745.2|WP_000356942.1|2065677_2066058_-|hypothetical-protein
MDKEQLKKYIYEYVKEYKEIPIYQLEDLFKEINHDYIGRTSITHDKDENIVFWSGWNKITMFALIELVKSEQLDLVYRGSFIMRYLLDGRVPNLPLAICYPEDGQQTDVPSWVPMVLRINKEEKIK
>NC_002745.2|WP_001047698.1|2065039_2065681_-|hypothetical-protein
MNLETIVNQFETRAGTLLRYYTGLLEHSKVQPCCFKLYNDPFDMVYVMMNSKLFGHVYIKDCKVRQSFELASPKHTEGLIRSIEGHYVGYELHDGKHLSISDMMASHLFEDEYFMYGLQTYAESNNSDVFEYLENGFDTDTLEGIQSSNTDVIANIEMLYQLATGINEPAPELVEGLKLVTEFVQDENATQEDYKALERKLNDLKASYYSLSK
>NC_002745.2|WP_001190615.1|2064248_2064590_-|hypothetical-protein
MQSIAEKETYHLPTEHLQVFNVIKNTSNKYITKTKILNQLGYEYNSSNERWLRRVINSLVYDYGYPIGCSYKPSERGYYIITTEQEKQQAMRSIKKLADGSMKRYEALKRIKV
>NC_002745.2|WP_000620857.1|2070411_2071086_+|helix-turn-helix-transcriptional-regulator
MIRNRLSELLSERGLKISRVAKDVKIARSSLTSMAQNDSEMIRYDAIDKLCSYLHISPSEFFEHNPINFDFTFDEEPNYKINDVFEGFEVTANITHAFSIENFDFEILVDVELDNRQKLNFDLDVSYKETEKITNSQHRFIFTIKNEDENIGLKKYVDSLSAGLKNLLFKKINQKLSGYVSEIIVKNIDDIEELFPNKGEKSTTLHKEILQTDSRLSSDIFKEY
>NC_002745.2|WP_000179343.1|2071099_2072272_+|tyrosine-type-recombinase/integrase
MASYEKRGNTWRYRISLGKDAETGKYKYISNSGFKRKSDAKHHAEMVERQLRNGDYIAPSTSTFKQVADDWISQYANEVKVSSVRAREKAIHHAIERFKNKPIQTIKKHDYQRFVNDISIQYSKNYVDSIVTSTNMIFKYAYDMKLIRILPSEGIKRPKKKVSVEELEDTEIHKKFLEKDELFQFLEIAKNHHSPQNSFEVFYTLAYTGMRAGELLALKWSDIDFENNTINITKTYYNPNNNKKQYQILTPKTESSIGKISVDPHVIKLLKNYKVDVQDTWKNELYVDNNFVFTDVNGYPLVIKKLQLWIKAILKKTNITNKQISTHSFRHTHCALLIEAGVHIKEIQERLRHKDINTTMNIYAKITNSYKKDASQKFSKLMENVSKDLF
>NC_002745.2|WP_000240642.1|2072340_2073957_-|chaperonin-GroEL
MVKQLKFSEDARQAMLRGVDQLANAVKVTIGPKGRNVVLDKEFTAPLITNDGVTIAKEIELEDPYENMGAKLVQEVANKTNEIAGDGTTTATVLAQAMIQEGLKNVTSGANPVGLRQGIDKAVKVAVEALHENSQKVENKNEIAQVGAISAADEEIGRYISEAMEKVGNDGVITIEESNGLNTELEVVEGMQFDRGYQSPYMVTDSDKMVAELERPYILVTDKKISSFQDILPLLEQVVQSNRPILIVADEVEGDALTNIVLNRMRGTFTAVAVKAPGFGDRRKAMLEDLAILTGAQVITDDLGLDLKDASIDMLGTASKVEVTKDNTTVVDGDGDENSIDARVSQLKSQIEETESDFDREKLQERLAKLAGGVAVIKVGAASETELKERKLRIEDALNSTRAAVEEGIVAGGGTALVNVYQKVSEIEAEGDIETGVNIVLKALTAPVRQIAENAGLEGSVIVERLKNAEPGVGFNAATNEWVNMLEAGIVDPTKVTRSALQHAASVAAMFLTTEAVVASIPEKNNDQPNMGGMPGMM
>NC_002745.2|WP_000917289.1|2074032_2074317_-|co-chaperone-GroES
MLKPIGNRVIIEKKEQEQTTKSGIVLTDSAKEKSNEGVIVAVGTGRLLNDGTRVTPEVKEGDRVVFQQYAGTEVKRDNETYLVLNEEDILAVIE
>NC_002745.2|WP_000197635.1|2074491_2075235_+|CPBP-family-intramembrane-metalloprotease
MTRLWASLLTVIIYILSQFLPLLIVKKLPFVQYSGIELTKAVIYIQLVLFLIAATTIILINLKIKNPTKLELEVKEPKKYIIPWALLGFALVMIYQMVVSIVLTQIYGGQQVSPNTEKLIIIARKIPIFIFFVSIIGPLLEEYVFRKVIFGELFNAIKGNRIVAFIIATTVSSLIFALAHNDFKFIPVYFGMGVIFSLAYVWTKRLAVPIIIHMLQNGFVVIFQLLNPEALKKATEQANFIYHIFIP
>NC_002745.2|WP_000120296.1|2075259_2076507_-|hypothetical-protein
MSYHWFKKMLLSTSILILSSSSLGLATHTVEAKDNLNGEKPTTNLNHNITSPSVNSEMNNNETGTPHESNQTGNEGTGSNSRDANPDSNNVKPDSNNQNPSTDSKPDPNNQNPSPNPKPDPDNPKPKPDPDKPKPNLDPKPDPDNPKPKPDPKPDPDKPKPNPDPKPDPDKPKPNPNPKPDPNKPNPNPSPDPDQPGDSNHSGGSKNGGTWNPNASDGSNQGQWQPNGNQGNSQNPTGNDFVSQRFLALANGAYKYNPYILNQINKLGKDYGEVTDEDIYNIIRKQNFSGNAYLNGLQQQSNYFRFQYFNPLKSERYYRNLDEQVLALITGEIGSMPDLKKPEDKPDSKQRSFEPHEKDDFTVVKKQEDNKKSASTAYSKSWLAIVCSMMVVFSIMLFLFVKRNKKKNKNESQRR
>NC_002745.2|WP_000522381.1|2076703_2077330_+|nitroreductase-family-protein
MGLFKKDKKAMTFDNAMEERRSIYNLKDSISISDDELESMIAHAVKHVPSSFNSQSTRIVLLLNDNNNKFWDNTKAILKEVMGENRDFEPTEQKIDNFKHSYGTILFYEDQDVVSGLQEQMPNYYDNFAIWSTQTNAMHQFAIWTALATKGIGASLQHYNPLVDEMTSKEFNIPKSWKLIAQMPFGDIREAAGEKTFNPVEDRFVIKK
>NC_002745.2|WP_000867951.1|2077690_2078476_+|carbon-nitrogen-family-hydrolase
MKVQIYQLPIIFGDSSKNETQITQWFEKNMNAEVDVVVLPEMWNNGYDLEHLNEKADNNLGQSFSFIKHLAEKYKVDIVAGSVSNIRNYQIFNTAFSVNKSGQLINEYDKVHLVPMLREHEFLTAGENVAEPFQLSDGTYVTQLICYDLRFPELLRYPARSGAKIAFYVAQWPMSRLQHWHSLLKARAIENNMFVIGTNSTGFDGNTEYAGHSIVINPNGDLVGELNESADILTVDLNLNEVEQQRENIPVFKSIKLDLYK
>NC_002745.2|WP_001549197.1|2079075_2079210_-|delta-lysin-family-phenol-soluble-modulin
MSCLILRIFILIKEGVISMAQDIISTIGDLVKWIIDTVNKFTKK
>NC_002745.2|WP_001105696.1|2079445_2080009_+|accessory-gene-regulator-ArgB-like-protein
MNYFDNKIDQFATYLQKRNNLDHIQFLQVRLGMQIIVGNFFKILVTYSISIFLSVFLFTLVTHLSYMLIRYNAHGAHAKSSILCYIQSILTFVFVPYFLINIDINFTYLLALSIIGLISVVIYAPAATKKQPIPIKLVKRKKYLSIIMYLLVLILSLIIHPFYAQFMLLGILVESITLLPIFFPKED

Crispr_ID: NC_002745_10

• CRISPR_ID: NC_002745_10
• CRISPR_location: 2206128-2206208
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers
• Cas_protein_info: csa3

Consensus repeat of NC_002745_10

Consensus_repeat	Method
CAACTTTAGTTGTTAGGGGCTCTT	CRISPRCasFinder

spacers of NC_002745_10

>10.1|2206152|33|NC_002745|CRISPRCasFinder
ATGCATGCGCTTAGCGCAGGCGCTCCTACTTTT

CRISPR arrays and Neighbor proteins around NC_002745_10

CRISPR arrays

The CRISPR arrays of NC_002745_10

>merge|NC_002745|10|2206128-2206208|CRISPRCasFinder
CAACTTTAGTTGTTAGGGGCTCTTATGCATGCGCTTAGCGCAGGCGCTCCTACTTTTCAACTTTAGTTGTTAGGGGCTTCT

>NC_002745|10|9|2206128-2206208|CRISPRCasFinder
CAACTTTAGTTGTTAGGGGCTCTT	ATGCATGCGCTTAGCGCAGGCGCTCCTACTTTT
CAACTTTAGTTGTTAGGGGCTTCT

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_002745.2|WP_001072201.1|2200192_2200924_+|23S-rRNA-(adenine(2058)-N(6))-methyltransferase-Erm(A)	unknown	unknown	gnl|CDD|366074
NC_002745.2|WP_001048266.1|2218144_2225590_-|DUF1542-domain-containing-protein	unknown	unknown	gnl|CDD|275089
NC_002745.2|WP_001557544.1|2202366_2204259_-|tyrosine-type-recombinase/integrase	unknown	unknown	gnl|CDD|271187
NC_002745.2|WP_000019734.1|2197064_2198042_+|CDF-family-zinc-efflux-transporter-CzrB	unknown	unknown	gnl|CDD|224151
NC_002745.2|WP_001024095.1|2195925_2196591_-|SDR-family-oxidoreductase	unknown	unknown	gnl|CDD|187554
NC_002745.2|WP_001292149.1|2216285_2216720_+|PTS-sugar-transporter-subunit-IIA	unknown	unknown	gnl|CDD|227014
NC_002745.2|WP_000361059.1|2201982_2202360_-|transposase	unknown	unknown	unknown
NC_002745.2|WP_000370925.1|2208143_2209001_-|Cof-type-HAD-IIB-family-hydrolase	unknown	unknown	gnl|CDD|223635
NC_002745.2|WP_000003759.1|2196742_2197063_+|Zn(II)-responsive-metalloregulatory-transcriptional-repressor-CzrA	csa3	COG0640_csa3_CAS-I-A	gnl|CDD|238042
NC_002745.2|WP_000067268.1|2201049_2201832_-|aminoglycoside-nucleotidyltransferase-ANT(9)-Ia	unknown	unknown	gnl|CDD|184296
NC_002745.2|WP_001092058.1|2198996_2199659_-|methyltransferase-domain-containing-protein	unknown	unknown	gnl|CDD|225136
NC_002745.2|WP_000334463.1|2210082_2211888_-|glutamine--fructose-6-phosphate-transaminase-(isomerizing)	unknown	unknown	gnl|CDD|234729
NC_002745.2|WP_000868132.1|2204255_2205341_-|tyrosine-type-recombinase/integrase	unknown	unknown	gnl|CDD|271186
NC_002745.2|WP_001802298.1|2206543_2206648_-|hypothetical-protein	unknown	unknown	unknown
NC_002745.2|WP_001127960.1|2194551_2195490_-|class-I-mannose-6-phosphate-isomerase	unknown	unknown	gnl|CDD|224399
NC_002745.2|WP_001792784.1|2207327_2207486_+|hypothetical-protein	unknown	unknown	unknown
NC_002745.2|WP_000908182.1|2209068_2209851_-|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl|CDD|224044
NC_002745.2|WP_000927371.1|2214141_2216274_+|BglG-family-transcription-antiterminator	unknown	unknown	gnl|CDD|226234
NC_002745.2|WP_000648723.1|2216719_2217826_+|mannitol-1-phosphate-5-dehydrogenase	unknown	unknown	gnl|CDD|235031
NC_002745.2|WP_000083807.1|2212568_2214107_+|PTS-mannitol-transporter-subunit-IICB	unknown	unknown	gnl|CDD|225123

HMMScan for Signature genes

Protein	Cas_name	Cas_description	E-value	Identity	Coverage
NC_002745.2|WP_000003759.1|2196742_2197063_+|Zn(II)-responsive-metalloregulatory-transcriptional-repressor-CzrA	csa3	COG0640_csa3_CAS-I-A	3.8e-21	70.4	0.1

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_002745.2|WP_001072201.1|2200192_2200924_+|23S-rRNA-(adenine(2058)-N(6))-methyltransferase-Erm(A)	gnl|CDD|366074	pfam00398, RrnaAD, Ribosomal RNA adenine dimethylase.	5.43116e-86
NC_002745.2|WP_001048266.1|2218144_2225590_-|DUF1542-domain-containing-protein	gnl|CDD|275089	TIGR04263, cell_wall_surface_anchor_family_protein, SasC/Mrp/FmtB intercellular aggregation domain. This domain, about 375 amino acids long on average, occurs only in Staphylococcus and Streptococcus. It occurs as a non-repetitive N-terminal domain of LPXTG-anchored surface proteins, including SasC, Mrp, and FmtB. This region in SasC was shown to be involved in cell aggregation and biofilm formation, which may explain the methicillin resistance seen for Mrp and FmtB.	1.54008e-108
NC_002745.2|WP_001557544.1|2202366_2204259_-|tyrosine-type-recombinase/integrase	gnl|CDD|271187	cd01187, INT_tnpB_C_Tn554, Putative Transposase B from transposon Tn554, C-terminal catalytic domain. This family includes putative Transposase B from transposon Tn554. It belongs to a DNA breaking-rejoining enzyme superfamily. The catalytic domain containing six conserved active site residues. The recombination reaction involves cleavage of a single strand of a DNA duplex by nucleophilic attack of a conserved tyrosine to give a 3' phosphotyrosyl protein-DNA adduct. In the second rejoining step, a terminal 5' hydroxyl attacks the covalent adduct to release the enzyme and generate duplex DNA. Many DNA breaking-rejoining enzymes also have N-terminal domains, which show little sequence or structure similarity.	6.6262e-52
NC_002745.2|WP_000019734.1|2197064_2198042_+|CDF-family-zinc-efflux-transporter-CzrB	gnl|CDD|224151	COG1230, CzcD, Co/Zn/Cd efflux system component [Inorganic ion transport and metabolism].	1.49165e-107
NC_002745.2|WP_001024095.1|2195925_2196591_-|SDR-family-oxidoreductase	gnl|CDD|187554	cd05243, SDR_a5, atypical (a) SDRs, subgroup 5. This subgroup contains atypical SDRs, some of which are identified as putative NAD(P)-dependent epimerases, one as a putative NAD-dependent epimerase/dehydratase. Atypical SDRs are distinct from classical SDRs. Members of this subgroup have a glycine-rich NAD(P)-binding motif that is very similar to the extended SDRs, GXXGXXG, and binds NADP. Generally, this subgroup has poor conservation of the active site tetrad; however, individual sequences do contain matches to the YXXXK active site motif, the upstream Ser, and there is a highly conserved Asp in place of the usual active site Asn throughout the subgroup. Atypical SDRs generally lack the catalytic residues characteristic of the SDRs, and their glycine-rich NAD(P)-binding motif is often different from the forms normally seen in classical or extended SDRs. Atypical SDRs include biliverdin IX beta reductase (BVR-B,aka flavin reductase), NMRa (a negative transcriptional regulator of various fungi), progesterone 5-beta-reductase like proteins, phenylcoumaran benzylic ether and pinoresinol-lariciresinol reductases, phenylpropene synthases, eugenol synthase, triphenylmethane reductase, isoflavone reductases, and others. SDRs are a functionally diverse family of oxidoreductases that have a single domain with a structurally conserved Rossmann fold, an NAD(P)(H)-binding region, and a structurally diverse C-terminal region. Sequence identity between different SDR enzymes is typically in the 15-30% range; they catalyze a wide range of activities including the metabolism of steroids, cofactors, carbohydrates, lipids, aromatic compounds, and amino acids, and act in redox sensing. Classical SDRs have an TGXXX[AG]XG cofactor binding motif and a YXXXK active site motif, with the Tyr residue of the active site motif serving as a critical catalytic residue (Tyr-151, human 15-hydroxyprostaglandin dehydrogenase numbering). In addition to the Tyr and Lys, there is often an upstream Ser and/or an Asn, contributing to the active site; while substrate binding is in the C-terminal region, which determines specificity. The standard reaction mechanism is a 4-pro-S hydride transfer and proton relay involving the conserved Tyr and Lys, a water molecule stabilized by Asn, and nicotinamide. In addition to the Rossmann fold core region typical of all SDRs, extended SDRs have a less conserved C-terminal extension of approximately 100 amino acids, and typically have a TGXXGXXG cofactor binding motif. Complex (multidomain) SDRs such as ketoreductase domains of fatty acid synthase have a GGXGXXG NAD(P)-binding motif and an altered active site motif (YXXXN). Fungal type ketoacyl reductases have a TGXXXGX(1-2)G NAD(P)-binding motif.	1.27122e-47
NC_002745.2|WP_000334463.1|2210082_2211888_-|glutamine--fructose-6-phosphate-transaminase-(isomerizing)	gnl|CDD|234729	PRK00331, PRK00331, isomerizing glutamine--fructose-6-phosphate transaminase.	0
NC_002745.2|WP_000370925.1|2208143_2209001_-|Cof-type-HAD-IIB-family-hydrolase	gnl|CDD|223635	COG0561, Cof, Predicted hydrolases of the HAD superfamily [General function prediction only].	6.8047e-59
NC_002745.2|WP_000003759.1|2196742_2197063_+|Zn(II)-responsive-metalloregulatory-transcriptional-repressor-CzrA	gnl|CDD|238042	cd00090, HTH_ARSR, Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to dissociate from DNA in the presence of metal ions.	1.8473e-17
NC_002745.2|WP_000067268.1|2201049_2201832_-|aminoglycoside-nucleotidyltransferase-ANT(9)-Ia	gnl|CDD|184296	PRK13746, PRK13746, aminoglycoside resistance protein; Provisional.	2.99486e-84
NC_002745.2|WP_001092058.1|2198996_2199659_-|methyltransferase-domain-containing-protein	gnl|CDD|225136	COG2226, UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis [Coenzyme metabolism].	5.63343e-23
NC_002745.2|WP_001292149.1|2216285_2216720_+|PTS-sugar-transporter-subunit-IIA	gnl|CDD|227014	COG4668, MtlA, Mannitol/fructose-specific phosphotransferase system, IIA domain [Carbohydrate transport and metabolism].	2.08822e-62
NC_002745.2|WP_000868132.1|2204255_2205341_-|tyrosine-type-recombinase/integrase	gnl|CDD|271186	cd01186, INT_tnpA_C_Tn554, Putative Transposase A from transposon Tn554, C-terminal catalytic domain. This family includes putative Transposase A from transposon Tn554. It belongs to a DNA breaking-rejoining enzyme superfamily. The catalytic domain contains six conserved active site residues. The recombination reaction involves cleavage of a single strand of a DNA duplex by nucleophilic attack of a conserved tyrosine to give a 3' phosphotyrosyl protein-DNA adduct. In the second rejoining step, a terminal 5' hydroxyl attacks the covalent adduct to release the enzyme and generate duplex DNA. Many DNA breaking-rejoining enzymes also have N-terminal domains, which show little sequence or structure similarity.	4.0175e-100
NC_002745.2|WP_000083807.1|2212568_2214107_+|PTS-mannitol-transporter-subunit-IICB	gnl|CDD|225123	COG2213, MtlA, Phosphotransferase system, mannitol-specific IIBC component [Carbohydrate transport and metabolism].	0
NC_002745.2|WP_001127960.1|2194551_2195490_-|class-I-mannose-6-phosphate-isomerase	gnl|CDD|224399	COG1482, ManA, Phosphomannose isomerase [Carbohydrate transport and metabolism].	7.24075e-129
NC_002745.2|WP_000648723.1|2216719_2217826_+|mannitol-1-phosphate-5-dehydrogenase	gnl|CDD|235031	PRK02318, PRK02318, mannitol-1-phosphate 5-dehydrogenase; Provisional.	0
NC_002745.2|WP_000908182.1|2209068_2209851_-|ABC-transporter-ATP-binding-protein	gnl|CDD|224044	COG1119, ModF, ABC-type molybdenum transport system, ATPase component/photorepair protein PhrA [Inorganic ion transport and metabolism].	1.29094e-106
NC_002745.2|WP_000927371.1|2214141_2216274_+|BglG-family-transcription-antiterminator	gnl|CDD|226234	COG3711, BglG, Transcriptional antiterminator [Transcription].	4.02509e-68

Protein sequences

>NC_002745.2|WP_000868132.1|2204255_2205341_-|tyrosine-type-recombinase/integrase
MKVQRIEVENKPYPLYLLLDKEYQLIEPVMKFIKYLDNTGKSPNTIKAYCYHLKLLYEFMEQRGVILNDINFELLADFVGWLRYPSASNVIDLQSKKAIREETTVNTILNVVMSFLDYLSRLGEFKSIDVFKQAKGRNFKGFLHHVNKGRYQKNVLKLRVKKKQIRTLRSKEVKQIIDACHTKRDKLILMLMYEGGLRIGEVLSLRLEDIVTWDNQIHLTPRDVNVNEAYIKLRKERTIHVSKELMSLYTDYLIYEYSEELEHDYVFISLKEGYFGKPLKYQSVLDLVRRIVKRTGIEFTSHMLRHTHATQLIREGWDVAFVQKRLGHAHVQTTLNTYVHLSDQDMKNEFNKYLERKEHKK
>NC_002745.2|WP_001557544.1|2202366_2204259_-|tyrosine-type-recombinase/integrase
MNASSKRKIISQSEISKKIAVMNEEMQGFWANNSWDIRKCPHPSAIELSKNPALRNRWVRFERVKNLWLRTELKYFYFYHLNNGIWNAKTVWIRKGTVINKMLDFLDLKYPSITSITEVPIEKAMTEYRTYLTKRGVRITTTNYKITANQEKTPVKANSYYVTNLKQFMEFYENFYFDGEEWDKDVWDRRNLPLPDDKVNPTQYEYTINFKGFRNTYFKQLVKRYCKLRLNVDSFSYVSDIAQRLKEFFNFLDMKFKQVQRVHQLTRVEIEAYLSELNMMGIKPSTITGRISILEGLFSTLLRLEWDDVPSKILIYSEDYPKIPRAKPRFIDEFVLEQLNSHLDKLPEYIATMTMIVQECGMRISELCTLKKGCLLEDKDGDFFLKYYQWKMKKEHIVPISKEVALLIKVREDKVSEEFPDSEYLFPRKDGSPLKQETFRGELNKLAYEQNIVDKSGEIYRFHAHAFRHTVGTRMINNGMPQHIVQKFLGHESPEMTSRYAHIFDETLKNEFTKFQEKLVTNNGDVLDLDEDNEVDDVELQWFKKNINAQVLPNGYCRLPVVAGGCPHANACLDCTHFCTSKQFLPQHEEQLERTEELLAIAKDKQWQRQVETNSRVKERLEQIIGSLTG
>NC_002745.2|WP_000361059.1|2201982_2202360_-|transposase
MDKQVRNTTEIVRLAKQKSKKTREKVDKAISKFSIEGKVINFNSIAKEANVSKSWLYKEHDIRQRIESLRERQITANVVSKPKKSSRSEEILIKTLKRRVMELEKENKKLQNQIQKLYGDLYNKE
>NC_002745.2|WP_000067268.1|2201049_2201832_-|aminoglycoside-nucleotidyltransferase-ANT(9)-Ia
MSNLINGKIPNQAIQTLKIVKDLFGSSIVGVYLFGSAVNGGLRINSDVDVLVVVNHSLPQLTRKKLTERLMTISGKIGNTDSVRPLEVTVINRSEVVPWQYPPKREFIYGEWLRGEFENGQIQEPSYDPDLAIVLAQARKNSISLFGPDSSSILVSVPLTDIRRAIKDSLPELIEGIKGDERNVILTLARMWQTVTTGEITSKDVAAEWAIPLLPKEHVTLLDIARKGYRGECDDKWEGLYSKVKALVKYMKNSIETSLN
>NC_002745.2|WP_001072201.1|2200192_2200924_+|23S-rRNA-(adenine(2058)-N(6))-methyltransferase-Erm(A)
MNQKNPKDTQNFITSKKHVKEILNHTNISKQDNVIEIGSGKGHFTKELVKMSRSVTAIEIDGGLCQVTKEAVNPSENIKVIQTDILKFSFPKHINYKIYGNIPYNISTDIVKRITFESQAKYSYLIVEKGFAKRLQNLQRALGLLLMVEMDIKMLKKVPPLYFHPKPSVDSVLIVLERHQPLISKKDYKKYRSFVYKWVNREYRVLFTKNQFRQALKHANVTNINKLSKEQFLSIFNSYKLFH
>NC_002745.2|WP_001092058.1|2198996_2199659_-|methyltransferase-domain-containing-protein
MNTIESQFDKVAEDYDFVNELLNDYSFFVSNMSPKKGRALDIGCGSGLLVEKLASYYDEVVGIDISNQMLDLAKSKRQLTNTVYLNMNAEQLNFNEKFDFIVSRTTFHHLDDIASVIQQMKELLNEEGRIVILDNVSEVETPPTYVYKLGAIQEFLPHCFKFGIKNAIRIYNHNTSKSWLEHLASDKYLSEQNYYDLYEKLLPGCQFHKMGWAMGVVWTK
>NC_002745.2|WP_000019734.1|2197064_2198042_+|CDF-family-zinc-efflux-transporter-CzrB
MSHSHHHDHMHSHVTTNNKKVLFISFLIIGLYMFIEIIGGLLANSLALLSDGIHMFSDTFSLGVALVAFIYAEKNATTTKTFGYKRFEVLAALFNGVTLFVISILIVFEAIKRFFVPSEVQSKEMLIISIIGLIVNIVVAFFMFKGGDTSHNLNMRGAFLHVIGDLLGSVGAITAAILIWAFGWTIADPIASILVSVIILKSAWGITKSSINILMEGTPSDVDIDEVITTIKKDSRIQSVHDCHVWTISNDMNALSCHVVVDHTLTMKECELLLENIEHDLLHLNIHHMTIQLETPNHKHDESIICSGTHSHSHNHHAHHHAHVH
>NC_002745.2|WP_000003759.1|2196742_2197063_+|Zn(II)-responsive-metalloregulatory-transcriptional-repressor-CzrA
MSEQYSEINTDTLERVTEIFKALGDYNRIRIMELLSVSEASVGHISHQLNLSQSNVSHQLKLLKSVHLVKAKRQGQSMIYSLDDIHVATMLKQAIHHANHPKESGL
>NC_002745.2|WP_001024095.1|2195925_2196591_-|SDR-family-oxidoreductase
MNILVIGANGGVGSLLVQQLAKENVPFTAGVRQSDQLNALKSQGMKAILVDVENDSIETLTETFKPFDKVIFSVGSGGNTGADKTIIVDLDGAVKSMIASKEANIKHYVMVSTYDSRRQAFDDSGDLKPYTIAKHYADDYLRRSGLNYTILHPGALTNAAGSGKIEAAQYFDGKGEIPREDVATVLKEIVTSNHFNHQEFQIISGEQDIKDALTQFEIEKD
>NC_002745.2|WP_001127960.1|2194551_2195490_-|class-I-mannose-6-phosphate-isomerase
MPLFLQPILKTKLWGGQRLSEFGYQLDNDTTGECWCVSAHPNGTSEIINGPYQGQTLDRIWSEHRELFGDFPSKDFPLLTKIVDARESLSIHVHPDNSYAYEHENGQYGKSECWYIIDAEEDAEIVIGTLAESREEVANHVQHGTIESILRYIKVKPGEFYFIPAGTVHTISSGILAYETMQSSDITYRLYDFNRQDNQYNDRPLNIEKALDVIQYNAPLPNILPESEIIENHKCTHIVSNDFFTLVKWEISGTLNYMKPREFCLVTVLEGEGQMIVDGEIFKLTTGTNFILTSEDLDSVFEGDFTLMISYV
>NC_002745.2|WP_001802298.1|2206543_2206648_-|hypothetical-protein
MLLLERTSMSDFEMLMVVLTIIGLVLISTQDHKK
>NC_002745.2|WP_001792784.1|2207327_2207486_+|hypothetical-protein
MSKSSDALFNSLTQSFELIEGVYNELVTDNLKIVMYKPRKESTSGRINRRFK
>NC_002745.2|WP_000370925.1|2208143_2209001_-|Cof-type-HAD-IIB-family-hydrolase
MDNVKAIFLDMDGTILHENNQASTYTKDVINQLREKGYKVFLATGRSHSEIHQLVPQDFAVNGIISSNGTIGEVDGEIIFKHGLSLAQVQQITNLAKRQQIYYEVFPFEGNRVSLKEDETWMRDMIRSQDPINGVSHSEWSSRQDALAGKIDWVTKFPEGEYSKIYLFSSNLEKITAFRDELKQNHVQLQISVSNSSRFNAETMAYQTDKGTGIKEMIAHFGIHQEETLVIGDSDNDRAMFEFGHYTVAMKNARPEIQALTSDVTAYTNEEDGAAKYLAKHFLAD
>NC_002745.2|WP_000908182.1|2209068_2209851_-|ABC-transporter-ATP-binding-protein
MLIQLDQIGRMKQGKTILKNISWQIAKGDKWILYGLNGAGKTTLLNILNAYEPATTGGVNLFGKMPGKVGYSAETVRQHIGFVSHSLLEKFQEGERVIDVVISGAFKSIGVYQDIDDEVRNEAHHLLKLVGISAKAQQYIGYLSTGEKQRVMIARALMGQPQVLILDEPAAGLDFIARESLLNILDSLSDSYPTLAMIYVTHFIEEITGNFTKILLLKDGESVQQGLIDDILTSENMSRFFQKNVAVQRWNNRFSMAMLE
>NC_002745.2|WP_000334463.1|2210082_2211888_-|glutamine--fructose-6-phosphate-transaminase-(isomerizing)
MCGIVGYIGYDNAKELLLKGLEKLEYRGYDSAGIAVVNDDNTTVFKEKGRIAELRKVADSSDFDGPVGIGHTRWATHGVPNHENSHPHQSSNGRFTLVHNGVIENYEELKGEYLQGVSFISETDTEVIVQLVEYFSNQGLSTEEAFTKVVSLLHGSYALGLLDAEDKDTIYVAKNKSPLLLGVGEGFNVIASDALAMLQVTSEYKEIHDHEIVIVKKDEVIIKDADGNVVERDSYIAEIDASDAEKGVYAHYMLKEIHEQPAVMRRIIQEYQDAEGNLKIDQDIINDVKEADRIYVIAAGTSYHAGLVGKEFLEKWAGVPTEVHVASEFVYNMPLLSEKPLFVYISQSGETADSRAVLVETNKLGHKSLTITNVAGSTLSREADHTLLLHAGPEIAVASTKAYTAQIAVLSILSQIVAKEHGREADIDLLRELAKVTTAIEAIVDDAPIMEQIATDFLETTRNAFFIGRTIDYNVSLEGALKLKEISYIQAEGFAGGELKHGTIALIEDGTPVVALATQENVNLSIRGNVKEVVARGAHPCIISMEGLEKEGDTYVIPHVHELLTPLVSVVALQLISYYAALHRDLDVDKPRNLAKSVTVE
>NC_002745.2|WP_000083807.1|2212568_2214107_+|PTS-mannitol-transporter-subunit-IICB
MSQTEEKKGIGRRVQAFGSFLSSMIMPNIGAFIAWGFIAAIFIDNGWLPNKDLATLAGPMITYLIPLLIAFSGGRLIYDLRGGIIAATATMGVIVALPDTPMLLGAMIMGPLVGWLMKKTDQLIQPRTPQGFEMLFNNFSAGILGFIMTIAGFKILAPLMKFIMHILSVAVEALVHAHLLPLVSILVEPAKIVFLNNAINHGVFTPLGADQAAKAGQSILYTIESNPGPGLGILLAYMIFGKGTAKATSYGAGIIHFLGGIHEIYFPYVLMRPLLFIAVILGGMTGVATYQATGFGFKSPASPGSFIVYCLNAPRGEFLHMLLGVFLAALVSFVVAALIMKFTREPKQDLEAATAQMENTKGKKSSVASKLVSSDKNVNTEENASGNVSETSSSDDDPEALLDNYNTEDVDAHNYNNINHVIFACDAGMGSSAMGASMLRNKFKKAGINDITVTNTAINQLPKDAQLVITQKKLTDRAIKQTPNAIHISVDNFLNSPRYEELLNNLKKDDQA
>NC_002745.2|WP_000927371.1|2214141_2216274_+|BglG-family-transcription-antiterminator
MLLSTREKEMIALLIKYHSQYITIHDIAQQLAVSSRTIHRELKGVEAYLTSFSLTLERANKKGLRIAGADSDLNDLKQSIAQHQTIDLSVEEQKVIIIYALIQAKEPVKQYSLAQEIGVSVQTLAKMLDDLELDLNKYQLSLSRKRGEGIYLVGTESKKREFLSQLMVNNLNSTSVYSVIENHFVFHSLNQIHKDFVDLERIFNVERLLMDYLSALPYQLTESSYLTLTVHIVLSISRIKNGEYVALNDDIYDSVQNTFEHKVASELADKLGQIYDVTFNQAEIAFITIHLRGAKRKNLNDTSLNNRCEENKIKAFVNKVEMISGMTFADLDTLVDGLTLHLNPAINRLQANIETYNPLTDMIKFKYPRLFENVRLALNDCWPDLIFPESEIAFIVLHFGGSIKNQGNRFLNILVVCSSGMGTSRLLSTRLEQVFSEIERITQASVSDLKSLDLSQYDGIISTVNLDIDSPYLTVNPLLPDSDISYVAQFLNTKSTFQETHDKSSNMIDKDDVHVETKDVDGNTSFENEQTSYLTSVFEKHLSDEKSEQLLHHMRSGLTLLDSVKIVSTEVKQWQTYIADYLYQCDVINDPTSFAELLEQRLIDNPGWILSPYPVAIPHLRDNMIKHPMILITVLEEPLTLPSIQNDNQTIKYMISMFIPDNDFMASLVSDLSEFLSLKLESIDTFMENPQELETLLRNKFLERIKKQFI
>NC_002745.2|WP_001292149.1|2216285_2216720_+|PTS-sugar-transporter-subunit-IIA
MSELFSNDNIFLNVNVNSQNEAIEKAGKALVDSGAVTDAYIQAMKDREQVVSTFMGNGLAIPHGTDEAKTNVIHSGLTLLQIPEGVDWDGEVVKVVVGIAGKDGEHLDLLSKIAITFSEEENVDRIVQAKSAEEIKQVFEEADA
>NC_002745.2|WP_000648723.1|2216719_2217826_+|mannitol-1-phosphate-5-dehydrogenase
MKAVHFGAGNIGRGFIGYILADNNVKVTFADVNEEIINALAHDHQYDVILADESKTTTRVNNVDAINSMQPSEALKQAILEADIITTAVGVNILPIIAKSFAPFLKEKTNHVNIVACENAIMATDTLKKAVLDITGPLGNNIHFANSAVDRIVPLQKNENILDVMVEPFYEWVVEKDAWYGPELNHIKYVDDLTPYIERKLLTVNTGHAYLAYAGKFAGKATVLDAVKDSSIEAGLRRVLAETSQYITNEFDFTEAEQAGYVEKIIDRFNNSYLSDEVTRVGRGTLRKIGPKDRIIKPLTYLYNKDLERTGLLNTAALLLKYDDTADQETVEKNNYIKEHGLKAFLSEYAKVDDGLADEIIEAYNSLS
>NC_002745.2|WP_001048266.1|2218144_2225590_-|DUF1542-domain-containing-protein
MNLFRQQKFSIRKFNVGIFSALIATVTFISTNPTTASAAEQNQPAQNQPAQPADANTQPNANAGAQANPAAQPANQGGQANPAGGAAQPAGQGNQADPNNAAQAQPGNQAAPANQAGQGNNQATPNNNATPANQTQPANAPAAAQPAAPVAANAQTQDPNASNTGEGSINTTLTFDDPAISTDENRQDPTVTVTDKVNGYSLINNGKIGFVNSELRRSDMFDKNNPQNYQAKGNVAALGRVNANDSTDHGNFNGITKTVNVKPDSELIINFTTMQTNSKQGATNLVIKDAKKNTELATVNVAKTGTAHLFKVPTDADRLDLQFIPDNTAVADASRITTNKDGYKYYSFIDNVGLFSGSHLYVKNRDLAPKATNNKEYTINTEIGNNGNFGASLKADQFKYEVTLPQGVTYVNDSLTTTFPNGNEDSTVLKNMTVNYDQTANKVTFTSQGVTTARGTHTKEVLFPDKSLKLSYKVNVANIDTPKNIDFNEKLTYRTASDVVINNAQPEVTLTADPFSVAVEMNKDALQQQVNSQVDNSHYTTASIAEYNKLKQQADTILNEDANHVETANRASQADIDGLVTKLQAALIDNQAAIAELDTKAQEKVTAAQQSKKVTQDEVAALVTKINNDKNNAIAEINKQTTSQGVTTEKDNGIAVLEQDVITPTVKPQAKQDIIQAVTTRKQQIKKSNASLQDEKDVANDKIGKIETKAIKDIDAATTNAQVEAIKTKAINDINQTTPATTAKAAALEEFDEVVQAQIDQAPLNPDTTNEEVAEAIERINAAKVSGVKAIEATTTAQDLERVKNEEIFKIENITDSTQTKMDAYKEVRQAATARKAQNATVSNATDEEVAEANAAVDAAQTEGLHDIQVVKSQQEVADTKAKVLDKINAIQTQAKVKPAADTEVENAYNTRKQEIQNSNASTTEEKEAAYTELDAKKQEARTNLDAANTNSDVTTAKDNGIAAINQVQAATTKKSDAKAEIAQKASERKTAIEAMNDSTTEEQQAAKDKVDQAVVTANADIDNATANTDVDNAKTTNEATIAAITPDANVKPAAKQAIADKVQAQETAIDANNGSTTEEKEAAKQQVQTEKTAADAAIDAAHSNVEVEAAKNAEIAKIEAIQPATTTKDNAKQAIATKANERKTAIAQTQDITAEEIAAANADVDNAVTQANSNIEAANSQNDVDQAKTTGETSIDQVTPTVNKKATARNEITAILNNKLQEIQATPDATDEEKQAADAEANTENGKANQAISAATTNAQVDEAKANAEAAINAVTPKVVKKQAAKDEIDQLQATQTNVINNDQNATNEEKEAAIQQLATAVTDAKNNITAATDDNGVDTAKDAGKNSIQSTQPATAVKSNAKNEVDQAVTTQNQAIDNTTGATTEEKNAAKDLVLKAKEKAYQDILNAQTTNDVTQIKDQAVADIQGITADTTIKDVAKDELATKANEQKALIAQTADATTEEKEQANQQVDAQLTQGNQNIENAQSIDDVNTAKDNAIQAIDPIQASTDVKTNARAELLTEMQNKITEILNNNETTNEEKGNDIGPVRAAYEEGLNNINAATTTGDVTTAKDTAVQKVQQLHANPVKKPAGKKELDQAAADKKTQIEQTPNASQQEINDAKQEVDTELNQAKTNVDQSSTNEYVDNAVKEGKAKINAVKTFSEYKKDALAKIEDAYNAKVNEADNSNASTSSEIAEAKQKLAELKQTADQNVNQATSKDDIEVQIHNDLDNINDYTIPTGKKESATTDLYAYADQKKNNISADTNATQDEKQQAIKQVDQNVQTALENINNGVDNGDVDDALTQGKAAIDTIQVDATVKPKANQAIEAKAEDTKESIDHSDQLTAEEKTEALAMIKQITDQAKQGITDATTTAEVEKAKAQGLEAFDNIQIDSTEKQKAIEELETALDQIEAGVNVDADATTEEKEAFTNALEDILSKATEDISDQTTNAEIATVKNSALEQLKAQRINPVVKKNALEAIREVVNKQIEIIKNADADASAKEIARTDLGRYFDRFADKLDKTQTNTEVAELQNVTIPAIEAIVPQNDPDANDTNNGTDNNDATANSNANATPENTGQPNVSETTDNGKADASPTTPNNSDAATGETTVTSATDDAKDKPQANNNSSADASTNSPTMDNDVTSKPEVESTNNGTTDKPVTETDNATPAESTTNNNSTTTATNENAPTGSTATAPTTASTEAASSADSKDNASVNDSKQNAEVNNSAESQSTNGKVAQPKSENKAKAEKDGRDSTNQSMVESTTETLPSADITEPNVPSNTSKDKEESTTNQTDAGQLKSETNVASNEADKSPSKADTEVSNKPSTSASSEAKDKMTSTNVSQKDDTATADTNDTQKSVGPVANNKAKDMQTNDTQKSVGSAANNKATQNDGANASPATVSNGSHSMHQDMLNVTKPEENKANAKSDQQGKVNKPKQQAKTLPDTGMSHNDDLPYAELALGAGMAFLIRRFTKKDQQTEE

Crispr_ID: NC_002745_11

• CRISPR_ID: NC_002745_11
• CRISPR_location: 2218449-2218534
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NC_002745_11

Consensus_repeat	Method
CCAACTGATTTTTGCGTATCATTAGT	CRISPRCasFinder

spacers of NC_002745_11

>11.1|2218475|34|NC_002745|CRISPRCasFinder
TTGCATATCTTTAGCTTTATTGTTTGCAACTGGG

CRISPR arrays and Neighbor proteins around NC_002745_11

CRISPR arrays

The CRISPR arrays of NC_002745_11

>merge|NC_002745|11|2218449-2218534|CRISPRCasFinder
CCAACTGATTTTTGCGTATCATTAGTTTGCATATCTTTAGCTTTATTGTTTGCAACTGGGCCAACTGATTTTTGCGTATCATTAGT

>NC_002745|11|10|2218449-2218534|CRISPRCasFinder
CCAACTGATTTTTGCGTATCATTAGT	TTGCATATCTTTAGCTTTATTGTTTGCAACTGGG
CCAACTGATTTTTGCGTATCATTAGT

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_002745.2|WP_000884735.1|2242101_2243289_-|UDPGP-type-1-family-protein	unknown	unknown	gnl|CDD|133036
NC_002745.2|WP_000636857.1|2239307_2239781_-|multidrug-efflux-transporter-SepA	unknown	unknown	gnl|CDD|374975
NC_002745.2|WP_000083807.1|2212568_2214107_+|PTS-mannitol-transporter-subunit-IICB	unknown	unknown	gnl|CDD|225123
NC_002745.2|WP_000334463.1|2210082_2211888_-|glutamine--fructose-6-phosphate-transaminase-(isomerizing)	unknown	unknown	gnl|CDD|234729
NC_002745.2|WP_000370925.1|2208143_2209001_-|Cof-type-HAD-IIB-family-hydrolase	unknown	unknown	gnl|CDD|223635
NC_002745.2|WP_000047255.1|2241399_2242083_-|hemolysin-III-family-protein	unknown	unknown	gnl|CDD|224191
NC_002745.2|WP_000167867.1|2229181_2230090_-|arginase	unknown	unknown	gnl|CDD|212515
NC_002745.2|WP_001237506.1|2239879_2241223_-|MFS-transporter	unknown	unknown	gnl|CDD|129794
NC_002745.2|WP_001292149.1|2216285_2216720_+|PTS-sugar-transporter-subunit-IIA	unknown	unknown	gnl|CDD|227014
NC_002745.2|WP_000347896.1|2228183_2228993_-|TIGR00159-family-protein	unknown	unknown	gnl|CDD|224539
NC_002745.2|WP_000868132.1|2204255_2205341_-|tyrosine-type-recombinase/integrase	unknown	unknown	gnl|CDD|271186
NC_002745.2|WP_001802298.1|2206543_2206648_-|hypothetical-protein	unknown	unknown	unknown
NC_002745.2|WP_001141007.1|2237542_2238985_-|multidrug-efflux-MFS-transporter-LmrS	unknown	unknown	gnl|CDD|129794
NC_002745.2|WP_000521495.1|2225867_2227223_-|phosphoglucosamine-mutase	unknown	unknown	gnl|CDD|237670
NC_002745.2|WP_000958531.1|2236330_2237395_-|P-loop-NTPase	unknown	unknown	gnl|CDD|378455
NC_002745.2|WP_000648723.1|2216719_2217826_+|mannitol-1-phosphate-5-dehydrogenase	unknown	unknown	gnl|CDD|235031
NC_002745.2|WP_000908182.1|2209068_2209851_-|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl|CDD|224044
NC_002745.2|WP_000927371.1|2214141_2216274_+|BglG-family-transcription-antiterminator	unknown	unknown	gnl|CDD|226234
NC_002745.2|WP_001792784.1|2207327_2207486_+|hypothetical-protein	unknown	unknown	unknown
NC_002745.2|WP_000894032.1|2227249_2228182_-|YbbR-like-domain-containing-protein	unknown	unknown	gnl|CDD|227193

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_002745.2|WP_000927371.1|2214141_2216274_+|BglG-family-transcription-antiterminator	gnl|CDD|226234	COG3711, BglG, Transcriptional antiterminator [Transcription].	4.02509e-68
NC_002745.2|WP_000636857.1|2239307_2239781_-|multidrug-efflux-transporter-SepA	gnl|CDD|374975	pfam17080, SepA, Multidrug Resistance efflux pump. SepA is a drug efflux protein that is involved in bacterial multidrug resistance. It is predicted to have four transmembrane domains.	3.20059e-30
NC_002745.2|WP_000894032.1|2227249_2228182_-|YbbR-like-domain-containing-protein	gnl|CDD|227193	COG4856, COG4856, Uncharacterized protein conserved in bacteria [Function unknown].	6.26423e-118
NC_002745.2|WP_000334463.1|2210082_2211888_-|glutamine--fructose-6-phosphate-transaminase-(isomerizing)	gnl|CDD|234729	PRK00331, PRK00331, isomerizing glutamine--fructose-6-phosphate transaminase.	0
NC_002745.2|WP_000370925.1|2208143_2209001_-|Cof-type-HAD-IIB-family-hydrolase	gnl|CDD|223635	COG0561, Cof, Predicted hydrolases of the HAD superfamily [General function prediction only].	6.8047e-59
NC_002745.2|WP_000167867.1|2229181_2230090_-|arginase	gnl|CDD|212515	cd09989, Arginase, Arginase family. This family includes arginase, also known as arginase-like amidino hydrolase family, and related proteins. Arginase is a binuclear Mn-dependent metalloenzyme and catalyzes hydrolysis of L-arginine to L-ornithine and urea (Arg, EC 3.5.3.1), the reaction being the fifth and final step in the urea cycle, providing the path for the disposal of nitrogenous compounds. Arginase controls cellular levels of arginine and ornithine which are involved in protein biosynthesis, and in production of creatine, polyamines, proline and nitric acid. In vertebrates, at least two isozymes have been identified: type I (ARG1) cytoplasmic or hepatic liver-type arginase and type II (ARG2) mitochondrial or non-hepatic arginase. Point mutations in human arginase ARG1 gene lead to hyperargininemia with consequent mental disorders, retarded development and early death. Hyperargininemia is associated with a several-fold increase in the activity of the mitochondrial arginase (ARG2), causing persistent ureagenesis in patients. ARG2 overexpression plays a critical role in the pathophysiology of cholesterol mediated endothelial dysfunction. Thus, arginase is a therapeutic target to treat asthma, erectile dysfunction, atherosclerosis and cancer.	9.8301e-146
NC_002745.2|WP_000884735.1|2242101_2243289_-|UDPGP-type-1-family-protein	gnl|CDD|133036	cd04193, UDPGlcNAc_PPase, UDPGlcNAc pyrophosphorylase catalayzes the synthesis of UDPGlcNAc. UDP-N-acetylglucosamine (UDPGlcNAc) pyrophosphorylase (UAP) (also named GlcNAc1P uridyltransferase), catalyzes the reversible conversion of UTP and GlcNAc1 to PPi and UDPGlcNAc. UDP-N-acetylglucosamine (UDPGlcNAc), the activated form of GlcNAc, is a key precursor of N- and O-linked glycosylations. It is essential for the synthesis of chitin (a major component of the fungal cell wall) and of the glycosylphosphatidylinositol (GPI) linker which anchors a variety of cell surface proteins to the plasma membrane. In bacteria, UDPGlcNAc represents an essential precursor for both peptidoglycan and lipopolysaccharide biosynthesis. Human UAP has two isoforms, resulting from alternative splicing of a single gene and differing by the presence or absence of 17 amino acids. UDPGlcNAc pyrophosphorylase shares significant sequence and structure conservation with UDPglucose pyrophosphorylase.	2.43588e-149
NC_002745.2|WP_001237506.1|2239879_2241223_-|MFS-transporter	gnl|CDD|129794	TIGR00711, Uncharacterized_MFS-type_transporter_YhcA, drug resistance transporter, EmrB/QacA subfamily. This subfamily of drug efflux proteins, a part of the major faciliator family, is predicted to have 14 potential membrane-spanning regions. Members with known activities include EmrB (multiple drug resistance efflux pump) in E. coli, FarB (antibacterial fatty acid resistance) in Neisseria gonorrhoeae, TcmA (tetracenomycin C resistance) in Streptomyces glaucescens, etc. In most cases, the efflux pump is described as having a second component encoded in the same operon, such as EmrA of E. coli. [Cellular processes, Toxin production and resistance, Transport and binding proteins, Other].	2.92638e-43
NC_002745.2|WP_001292149.1|2216285_2216720_+|PTS-sugar-transporter-subunit-IIA	gnl|CDD|227014	COG4668, MtlA, Mannitol/fructose-specific phosphotransferase system, IIA domain [Carbohydrate transport and metabolism].	2.08822e-62
NC_002745.2|WP_000868132.1|2204255_2205341_-|tyrosine-type-recombinase/integrase	gnl|CDD|271186	cd01186, INT_tnpA_C_Tn554, Putative Transposase A from transposon Tn554, C-terminal catalytic domain. This family includes putative Transposase A from transposon Tn554. It belongs to a DNA breaking-rejoining enzyme superfamily. The catalytic domain contains six conserved active site residues. The recombination reaction involves cleavage of a single strand of a DNA duplex by nucleophilic attack of a conserved tyrosine to give a 3' phosphotyrosyl protein-DNA adduct. In the second rejoining step, a terminal 5' hydroxyl attacks the covalent adduct to release the enzyme and generate duplex DNA. Many DNA breaking-rejoining enzymes also have N-terminal domains, which show little sequence or structure similarity.	4.0175e-100
NC_002745.2|WP_000083807.1|2212568_2214107_+|PTS-mannitol-transporter-subunit-IICB	gnl|CDD|225123	COG2213, MtlA, Phosphotransferase system, mannitol-specific IIBC component [Carbohydrate transport and metabolism].	0
NC_002745.2|WP_001141007.1|2237542_2238985_-|multidrug-efflux-MFS-transporter-LmrS	gnl|CDD|129794	TIGR00711, Uncharacterized_MFS-type_transporter_YhcA, drug resistance transporter, EmrB/QacA subfamily. This subfamily of drug efflux proteins, a part of the major faciliator family, is predicted to have 14 potential membrane-spanning regions. Members with known activities include EmrB (multiple drug resistance efflux pump) in E. coli, FarB (antibacterial fatty acid resistance) in Neisseria gonorrhoeae, TcmA (tetracenomycin C resistance) in Streptomyces glaucescens, etc. In most cases, the efflux pump is described as having a second component encoded in the same operon, such as EmrA of E. coli. [Cellular processes, Toxin production and resistance, Transport and binding proteins, Other].	1.85929e-81
NC_002745.2|WP_000521495.1|2225867_2227223_-|phosphoglucosamine-mutase	gnl|CDD|237670	PRK14316, glmM, phosphoglucosamine mutase; Provisional.	0
NC_002745.2|WP_000958531.1|2236330_2237395_-|P-loop-NTPase	gnl|CDD|378455	pfam10609, ParA, NUBPL iron-transfer P-loop NTPase. This family contains ATPases involved in plasmid partitioning. It also contains the cytosolic Fe-S cluster assembling factor NBP35 which is required for biogenesis and export of both ribosomal subunits.	6.43129e-115
NC_002745.2|WP_000648723.1|2216719_2217826_+|mannitol-1-phosphate-5-dehydrogenase	gnl|CDD|235031	PRK02318, PRK02318, mannitol-1-phosphate 5-dehydrogenase; Provisional.	0
NC_002745.2|WP_000908182.1|2209068_2209851_-|ABC-transporter-ATP-binding-protein	gnl|CDD|224044	COG1119, ModF, ABC-type molybdenum transport system, ATPase component/photorepair protein PhrA [Inorganic ion transport and metabolism].	1.29094e-106
NC_002745.2|WP_000347896.1|2228183_2228993_-|TIGR00159-family-protein	gnl|CDD|224539	COG1624, COG1624, Uncharacterized conserved protein [Function unknown].	2.13611e-103
NC_002745.2|WP_000047255.1|2241399_2242083_-|hemolysin-III-family-protein	gnl|CDD|224191	COG1272, COG1272, Predicted membrane protein, hemolysin III homolog [General function prediction only].	2.41003e-66

Protein sequences

>NC_002745.2|WP_000648723.1|2216719_2217826_+|mannitol-1-phosphate-5-dehydrogenase
MKAVHFGAGNIGRGFIGYILADNNVKVTFADVNEEIINALAHDHQYDVILADESKTTTRVNNVDAINSMQPSEALKQAILEADIITTAVGVNILPIIAKSFAPFLKEKTNHVNIVACENAIMATDTLKKAVLDITGPLGNNIHFANSAVDRIVPLQKNENILDVMVEPFYEWVVEKDAWYGPELNHIKYVDDLTPYIERKLLTVNTGHAYLAYAGKFAGKATVLDAVKDSSIEAGLRRVLAETSQYITNEFDFTEAEQAGYVEKIIDRFNNSYLSDEVTRVGRGTLRKIGPKDRIIKPLTYLYNKDLERTGLLNTAALLLKYDDTADQETVEKNNYIKEHGLKAFLSEYAKVDDGLADEIIEAYNSLS
>NC_002745.2|WP_001292149.1|2216285_2216720_+|PTS-sugar-transporter-subunit-IIA
MSELFSNDNIFLNVNVNSQNEAIEKAGKALVDSGAVTDAYIQAMKDREQVVSTFMGNGLAIPHGTDEAKTNVIHSGLTLLQIPEGVDWDGEVVKVVVGIAGKDGEHLDLLSKIAITFSEEENVDRIVQAKSAEEIKQVFEEADA
>NC_002745.2|WP_000927371.1|2214141_2216274_+|BglG-family-transcription-antiterminator
MLLSTREKEMIALLIKYHSQYITIHDIAQQLAVSSRTIHRELKGVEAYLTSFSLTLERANKKGLRIAGADSDLNDLKQSIAQHQTIDLSVEEQKVIIIYALIQAKEPVKQYSLAQEIGVSVQTLAKMLDDLELDLNKYQLSLSRKRGEGIYLVGTESKKREFLSQLMVNNLNSTSVYSVIENHFVFHSLNQIHKDFVDLERIFNVERLLMDYLSALPYQLTESSYLTLTVHIVLSISRIKNGEYVALNDDIYDSVQNTFEHKVASELADKLGQIYDVTFNQAEIAFITIHLRGAKRKNLNDTSLNNRCEENKIKAFVNKVEMISGMTFADLDTLVDGLTLHLNPAINRLQANIETYNPLTDMIKFKYPRLFENVRLALNDCWPDLIFPESEIAFIVLHFGGSIKNQGNRFLNILVVCSSGMGTSRLLSTRLEQVFSEIERITQASVSDLKSLDLSQYDGIISTVNLDIDSPYLTVNPLLPDSDISYVAQFLNTKSTFQETHDKSSNMIDKDDVHVETKDVDGNTSFENEQTSYLTSVFEKHLSDEKSEQLLHHMRSGLTLLDSVKIVSTEVKQWQTYIADYLYQCDVINDPTSFAELLEQRLIDNPGWILSPYPVAIPHLRDNMIKHPMILITVLEEPLTLPSIQNDNQTIKYMISMFIPDNDFMASLVSDLSEFLSLKLESIDTFMENPQELETLLRNKFLERIKKQFI
>NC_002745.2|WP_000083807.1|2212568_2214107_+|PTS-mannitol-transporter-subunit-IICB
MSQTEEKKGIGRRVQAFGSFLSSMIMPNIGAFIAWGFIAAIFIDNGWLPNKDLATLAGPMITYLIPLLIAFSGGRLIYDLRGGIIAATATMGVIVALPDTPMLLGAMIMGPLVGWLMKKTDQLIQPRTPQGFEMLFNNFSAGILGFIMTIAGFKILAPLMKFIMHILSVAVEALVHAHLLPLVSILVEPAKIVFLNNAINHGVFTPLGADQAAKAGQSILYTIESNPGPGLGILLAYMIFGKGTAKATSYGAGIIHFLGGIHEIYFPYVLMRPLLFIAVILGGMTGVATYQATGFGFKSPASPGSFIVYCLNAPRGEFLHMLLGVFLAALVSFVVAALIMKFTREPKQDLEAATAQMENTKGKKSSVASKLVSSDKNVNTEENASGNVSETSSSDDDPEALLDNYNTEDVDAHNYNNINHVIFACDAGMGSSAMGASMLRNKFKKAGINDITVTNTAINQLPKDAQLVITQKKLTDRAIKQTPNAIHISVDNFLNSPRYEELLNNLKKDDQA
>NC_002745.2|WP_000334463.1|2210082_2211888_-|glutamine--fructose-6-phosphate-transaminase-(isomerizing)
MCGIVGYIGYDNAKELLLKGLEKLEYRGYDSAGIAVVNDDNTTVFKEKGRIAELRKVADSSDFDGPVGIGHTRWATHGVPNHENSHPHQSSNGRFTLVHNGVIENYEELKGEYLQGVSFISETDTEVIVQLVEYFSNQGLSTEEAFTKVVSLLHGSYALGLLDAEDKDTIYVAKNKSPLLLGVGEGFNVIASDALAMLQVTSEYKEIHDHEIVIVKKDEVIIKDADGNVVERDSYIAEIDASDAEKGVYAHYMLKEIHEQPAVMRRIIQEYQDAEGNLKIDQDIINDVKEADRIYVIAAGTSYHAGLVGKEFLEKWAGVPTEVHVASEFVYNMPLLSEKPLFVYISQSGETADSRAVLVETNKLGHKSLTITNVAGSTLSREADHTLLLHAGPEIAVASTKAYTAQIAVLSILSQIVAKEHGREADIDLLRELAKVTTAIEAIVDDAPIMEQIATDFLETTRNAFFIGRTIDYNVSLEGALKLKEISYIQAEGFAGGELKHGTIALIEDGTPVVALATQENVNLSIRGNVKEVVARGAHPCIISMEGLEKEGDTYVIPHVHELLTPLVSVVALQLISYYAALHRDLDVDKPRNLAKSVTVE
>NC_002745.2|WP_000908182.1|2209068_2209851_-|ABC-transporter-ATP-binding-protein
MLIQLDQIGRMKQGKTILKNISWQIAKGDKWILYGLNGAGKTTLLNILNAYEPATTGGVNLFGKMPGKVGYSAETVRQHIGFVSHSLLEKFQEGERVIDVVISGAFKSIGVYQDIDDEVRNEAHHLLKLVGISAKAQQYIGYLSTGEKQRVMIARALMGQPQVLILDEPAAGLDFIARESLLNILDSLSDSYPTLAMIYVTHFIEEITGNFTKILLLKDGESVQQGLIDDILTSENMSRFFQKNVAVQRWNNRFSMAMLE
>NC_002745.2|WP_000370925.1|2208143_2209001_-|Cof-type-HAD-IIB-family-hydrolase
MDNVKAIFLDMDGTILHENNQASTYTKDVINQLREKGYKVFLATGRSHSEIHQLVPQDFAVNGIISSNGTIGEVDGEIIFKHGLSLAQVQQITNLAKRQQIYYEVFPFEGNRVSLKEDETWMRDMIRSQDPINGVSHSEWSSRQDALAGKIDWVTKFPEGEYSKIYLFSSNLEKITAFRDELKQNHVQLQISVSNSSRFNAETMAYQTDKGTGIKEMIAHFGIHQEETLVIGDSDNDRAMFEFGHYTVAMKNARPEIQALTSDVTAYTNEEDGAAKYLAKHFLAD
>NC_002745.2|WP_001792784.1|2207327_2207486_+|hypothetical-protein
MSKSSDALFNSLTQSFELIEGVYNELVTDNLKIVMYKPRKESTSGRINRRFK
>NC_002745.2|WP_001802298.1|2206543_2206648_-|hypothetical-protein
MLLLERTSMSDFEMLMVVLTIIGLVLISTQDHKK
>NC_002745.2|WP_000868132.1|2204255_2205341_-|tyrosine-type-recombinase/integrase
MKVQRIEVENKPYPLYLLLDKEYQLIEPVMKFIKYLDNTGKSPNTIKAYCYHLKLLYEFMEQRGVILNDINFELLADFVGWLRYPSASNVIDLQSKKAIREETTVNTILNVVMSFLDYLSRLGEFKSIDVFKQAKGRNFKGFLHHVNKGRYQKNVLKLRVKKKQIRTLRSKEVKQIIDACHTKRDKLILMLMYEGGLRIGEVLSLRLEDIVTWDNQIHLTPRDVNVNEAYIKLRKERTIHVSKELMSLYTDYLIYEYSEELEHDYVFISLKEGYFGKPLKYQSVLDLVRRIVKRTGIEFTSHMLRHTHATQLIREGWDVAFVQKRLGHAHVQTTLNTYVHLSDQDMKNEFNKYLERKEHKK
>NC_002745.2|WP_000521495.1|2225867_2227223_-|phosphoglucosamine-mutase
MGKYFGTDGVRGVANQELTPELAFKLGRYGGYVLAHNKGEKHPRVLVGRDTRVSGEMLESALIAGLISIGAEVMRLGIISTPGVAYLTRDMGAELGVMISASHNPVADNGIKFFGSDGFKLSDEQENEIEALLDQENPELPRPVGNDIVHYSDYFEGAQKYLSYLKSTVDVNFEGLKIVLDGANGSTSSLAPFLFGDLEADTETIGCSPDGYNINEKCGSTHPEKLAEKVVETESDFGLAFDGDGDRIIAVDENGQIVDGDQIMFIIGQEMHKNQELNNDMIVSTVMSNLGFYKALEQEGIKSNKTKVGDRYVVEEMRRGNYNLGGEQSGHIVMMDYNTTGDGLLTGIQLASVIKMTGKSLSELAGQMKKYPQSLINVRVTDKYRVEENVDVKEVMTKVEVEMNGEGRILVRPSGTEPLVRVMVEAATDEDAERFAQQIADVVQDKMGLDK
>NC_002745.2|WP_000894032.1|2227249_2228182_-|YbbR-like-domain-containing-protein
MLESKWGLRFIAFLLALFFFLSVNNVFGNIFNTGNLGQKSSKTIQDVPVEILYNTKDLHLTKAPETVNVTISGPQSKIIKIENPEDLRVVIDLSNAKAGKYQEKYQVKGLADDIHYSVKPKLANITLENKVTKKMTVQPDVSQSDIDPLYKITKQEVSPQTVKVTGGEEQLNDIAYLKATFKTNKKINGDTKDVAEVTAFDKKLNKLNVSIQPNEVNLQVKVEPFSKKVKVNVKQKGSLADDKELSSIDLEDKEIEIFGSRDDLQNISEVDAEVDLDGISESTEKTVKINLPEHVTKAQPSETKAYINVK
>NC_002745.2|WP_000347896.1|2228183_2228993_-|TIGR00159-family-protein
MDFSNFFQNLSTLKIVTSILDLLIVWYVLYLLITVFKGTKAIQLLKGILVIVIGQQISMILNLTATSKLFDIVIQWGVLALIVIFQPEIRRALEQLGRGSFLKRYTSNTYSKDEEKLIQSVSKAVQYMAKRRIGALIVFEKETGLQDYIETGIAMDSNISQELLINVFIPNTPLHDGAMIIQGTKIAAAASYLPLSDSPKISKSLGTRHRAAVGISEVSDAFTVIVSEETGDISVTFDGKLRRDISNEIFEELLAEHWFGTRFQKKGVK
>NC_002745.2|WP_000167867.1|2229181_2230090_-|arginase
MTKTKAIDIIGAPSTFGQRKLGVDLGPTAIRYAGLISRLKQLDLDVYDKGDIKVPAVNIEKFHSEQKGLRNYDEIIDVNQKLNKEVSASIENNRFPLVLGGDHSIAVGSVSAISKHYNNLGVIWYDAHGDLNIPEESPSGNIHGMPLRILTGEGPKELLELNSNVIKPENIVLIGMRDLDKGERQFIKDHNIKTFTMSDIDKLGIKEVIENTIEYLKSRNVDGVHLSLDVDALDPLETPGTGTRVLGGLSYRESHFALELLHQSHLISSMDLVEVNPLIDSNNHTAEQAVSLVGTFFGETLL
>NC_002745.2|WP_000958531.1|2236330_2237395_-|P-loop-NTPase
MLTVDQVKELVGEIKDPIIDVPLKETEGIVEVSIKEEKEHVSVKLAMAQLGGAPQLDLQMAVVNALKENGAKTVGIRFETLPEEKVNQFKPKEENKPKTIEGLLSQNNPVEFIAIASGKGGVGKSTVAVNLAVALAREGKKVGLVDADIYGFSVPDMMGIDEKPGIKGKEVIPVERHGVKVISMAFFVEENAPVIWRGPMLGKMLTNFFTEVKWGDIEYLILDLPPGTGDVALDVHTMLPSSKEIIVTTPHPTAAFVAARAGAMAKHTDHSILGVIENMSYFESKETGNKEYVFGKGGGTKLADELNTQLLGELPLEQPSWNPKDFAPSIYQSDDRLGKIYSSIAQKVIAATNK
>NC_002745.2|WP_001141007.1|2237542_2238985_-|multidrug-efflux-MFS-transporter-LmrS
MAKVELTTRRRNFIVAVMLISAFVAILNQTLLNTALPSIMRELNINESTSQWLVTGFMLVNGVMIPLTAYLMDRIKTRPLYLAAMGTFLLGSIVAALAPNFGVLMLARVIQAMGAGVLMPLMQFTLFTLFSKEHRGFAMGLAGLVIQFAPAIGPTVTGLIIDQASWRVPFIIIVGIALVAFVFGLVSISSYNEVKYTKLDKRSVMYSTIGFGLMLYAFSSAGDLGFTSPIVIGALIISMVIIYLFIRRQFNITNVLLNLRVFKNRTFALCTISSMIIMMSMVGPALLIPLYVQNSLSLSALLSGLVIMPGAIINGIMSVFTGKFYDKYGPRPLIYTGFTILTITTIMLCFLHTDTSYTYLIVVYAIRMFSVSLLMMPINTTGINSLRNEEISHGTAIMNFGRVMAGSLGTALMVTLMSFGAKIFLSTSPSHLTATEIKQQSIAIGVDISFAFVAVLVMAAYVIALFIREPKEIESNRRKF
>NC_002745.2|WP_000636857.1|2239307_2239781_-|multidrug-efflux-transporter-SepA
MIVNYLKHKFYNLLTTMIVLFIFVLSGAIFLTFLGFGLYGLSRILIYFRLGDFTYNRSMYDNLLYYGSYIIFGYFIIFAVEHLMDYFRKMLPENAYFRGATFHLISYTVATTLFYFIIHLNYVYINIDFWVIMVIIGFLYVCKLQFYPESKNLNNRK
>NC_002745.2|WP_001237506.1|2239879_2241223_-|MFS-transporter
MRLKSIITVIALILIMFMSAIESSIISLALPTIKQDLNAGNLISLIFTAYFIALVIANPIVGELLSRFKIIYVAIAGLLLFSIGSFMCGLSTNFTMLIISRVIQGFGSGVLMSLSQIVPKLAFEIPLRYKIMGIVGSVWGISSIIGPLLGGGILEFATWHWLFYINIPIAIIAIILVIWTFHFPEEETVAKSKFDTKGLTLFYVFIGLIMFALLNQQLLLLNFLSFILAIVVAMCLFKVEKHVSSPFLPVVEFNRSITLVFITDLLTAICLMGFNLYIPVYLQEQLGLSPLQSGLVIFPLSVAWITLNFNLHRIEAKLSRKVIYLLSFTLLLVSSIIISFGIKLPVLIAFVLILAGLSFGYIYTKDSVIVQEETSPLQMKKMMSFYGLTKNLGASIGSTIMGYLYAIQSGIFGPNLHNVLSAVAVISIGLIVLWVVFFKEQSSQSKE
>NC_002745.2|WP_000047255.1|2241399_2242083_-|hemolysin-III-family-protein
MSKSTKKSNDTIVETFKDIIPLSFGEEIGNAASHGVAALLTLLVLPYAAVHSYIAHGTLASVSMSIYVISIFMMFISSTIYHSMQNETPHKYILRIIDHSMIYVAISGTYTPILLTVVGGWIGWTVFILLWGTTLWGILYKSIAVKVNQKLSLIVYLVMGWVGIILLPIIFIRTSWIFILFIFLGGVSYTIGAWFYAQKNRPYFHMIWHIFIVIASLLHLIAILYFM
>NC_002745.2|WP_000884735.1|2242101_2243289_-|UDPGP-type-1-family-protein
MLDKNQLAKYKQDHLCEYEKIMSNNEKEALEEKVASLDLDFIAKLYNDLYINKKTIDDVSAVSEVKYDIKSQMSDDEIKRLEEQGLQAIKEGQFAVLLMAGGQGTRLGYKGPKGSFEIEGVSLFELQANQLKTLNHQSGHTIQWYIMTSDINHEETLAYFEAHSYFGYDQEAIHFFKQDNIVALSEEGKLILNQQGRIMETPNGNGGVFKSLDKAGYLEEMSNNGVKYIFLNNIDNVLVKVLDPLFAGFTVEHDYDITSKTIQPKPGESVGRLVNVDCKDTVLEYSELDPEVANQFNNANIGIHAFKLGFILNAVNRELPYHLAIKNLKQLDENFGVIEQPTLKFELFYFDIFTYGTSFVTLQVPREEEFSPLKNKEGKDSVATATEDLRRMGLI

Crispr_ID: NC_002745_12

• CRISPR_ID: NC_002745_12
• CRISPR_location: 2326428-2326508
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NC_002745_12

Consensus_repeat	Method
TCTATGTTGGGGCCCCGCCAACTTG	CRISPRCasFinder

spacers of NC_002745_12

>12.1|2326453|31|NC_002745|CRISPRCasFinder
CACATTATTGTAAGCTGACTTTCTGTCAGCT

CRISPR arrays and Neighbor proteins around NC_002745_12

CRISPR arrays

The CRISPR arrays of NC_002745_12

>merge|NC_002745|12|2326428-2326508|CRISPRCasFinder
TCTATGTTGGGGCCCCGCCAACTTGCACATTATTGTAAGCTGACTTTCTGTCAGCTTCTGTGTTGGGGCCCCGCCAACTTG

>NC_002745|12|11|2326428-2326508|CRISPRCasFinder
TCTATGTTGGGGCCCCGCCAACTTG	CACATTATTGTAAGCTGACTTTCTGTCAGCT
TCTGTGTTGGGGCCCCGCCAACTTG

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_002745.2|WP_000230173.1|2326651_2327674_-|GTP-3',8-cyclase-MoaA	unknown	unknown	gnl|CDD|274250
NC_002745.2|WP_000951058.1|2323978_2324419_+|winged-helix-DNA-binding-protein	unknown	unknown	gnl|CDD|197670
NC_002745.2|WP_000913024.1|2333009_2333615_-|ATP-binding-cassette-domain-containing-protein	unknown	unknown	gnl|CDD|226628
NC_002745.2|WP_000503822.1|2331298_2331805_-|molybdenum-cofactor-biosynthesis-protein-MoaB	unknown	unknown	gnl|CDD|223595
NC_002745.2|WP_000643986.1|2327693_2328293_-|molybdenum-cofactor-guanylyltransferase-MobA	unknown	unknown	gnl|CDD|234725
NC_002745.2|WP_000600967.1|2323052_2323817_-|VOC-family-protein	unknown	unknown	gnl|CDD|379203
NC_002745.2|WP_000184404.1|2324411_2325623_+|MFS-transporter	unknown	unknown	gnl|CDD|341042
NC_002745.2|WP_000866971.1|2328299_2328533_-|molybdopterin-converting-factor-subunit-1	unknown	unknown	gnl|CDD|340452
NC_002745.2|WP_001549681.1|2322809_2323061_+|hypothetical-protein	unknown	unknown	unknown
NC_002745.2|WP_000076930.1|2331835_2332840_-|ThiF-family-adenylyltransferase	unknown	unknown	gnl|CDD|181084
NC_002745.2|WP_000808495.1|2328538_2328985_-|molybdenum-cofactor-biosynthesis-protein-MoaE	unknown	unknown	gnl|CDD|223391
NC_002745.2|WP_000051210.1|2316961_2317126_+|hypothetical-protein	unknown	unknown	unknown
NC_002745.2|WP_000259717.1|2329480_2330740_-|molybdopterin-molybdotransferase-MoeA	unknown	unknown	gnl|CDD|238452
NC_002745.2|WP_000134526.1|2330802_2331297_+|cyclic-pyranopterin-monophosphate-synthase-MoaC	unknown	unknown	gnl|CDD|236483
NC_002745.2|WP_001792132.1|2326200_2326386_+|hypothetical-protein	unknown	unknown	unknown
NC_002745.2|WP_000066900.1|2325724_2326075_-|HTH-type-transcriptional-regulator-SarV	unknown	unknown	gnl|CDD|130944
NC_002745.2|WP_000413862.1|2321155_2322421_-|lipid-II:glycine-glycyltransferase-FemX	unknown	unknown	gnl|CDD|225224
NC_002745.2|WP_001161085.1|2317370_2317688_+|hypothetical-protein	unknown	unknown	unknown
NC_002745.2|WP_000602950.1|2328998_2329484_-|molybdopterin-guanine-dinucleotide-biosynthesis-protein-B	unknown	unknown	gnl|CDD|224677
NC_002745.2|WP_000592307.1|2317871_2321039_-|efflux-RND-transporter-permease-subunit	unknown	unknown	gnl|CDD|223911

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_002745.2|WP_000230173.1|2326651_2327674_-|GTP-3',8-cyclase-MoaA	gnl|CDD|274250	TIGR02666, Cyclic_pyranopterin_monophosphate_synthase, molybdenum cofactor biosynthesis protein A, bacterial. The model for this family describes molybdenum cofactor biosynthesis protein A, or MoaA, as found in bacteria. It does not include the family of probable functional equivalent proteins from the archaea. MoaA works together with MoaC to synthesize precursor Z from guanine. [Biosynthesis of cofactors, prosthetic groups, and carriers, Molybdopterin].	1.0538e-165
NC_002745.2|WP_000951058.1|2323978_2324419_+|winged-helix-DNA-binding-protein	gnl|CDD|197670	smart00347, HTH_MARR, helix_turn_helix multiple antibiotic resistance protein.	2.35323e-15
NC_002745.2|WP_000913024.1|2333009_2333615_-|ATP-binding-cassette-domain-containing-protein	gnl|CDD|226628	COG4148, ModC, ABC-type molybdate transport system, ATPase component [Inorganic ion transport and metabolism].	1.78595e-116
NC_002745.2|WP_000503822.1|2331298_2331805_-|molybdenum-cofactor-biosynthesis-protein-MoaB	gnl|CDD|223595	COG0521, MoaB, Molybdopterin biosynthesis enzymes [Coenzyme metabolism].	2.42221e-64
NC_002745.2|WP_000643986.1|2327693_2328293_-|molybdenum-cofactor-guanylyltransferase-MobA	gnl|CDD|234725	PRK00317, mobA, molybdopterin-guanine dinucleotide biosynthesis protein MobA; Reviewed.	2.15389e-66
NC_002745.2|WP_000600967.1|2323052_2323817_-|VOC-family-protein	gnl|CDD|379203	pfam13468, Glyoxalase_3, Glyoxalase-like domain. This domain is related to the Glyoxalase domain pfam00903.	1.50083e-38
NC_002745.2|WP_000184404.1|2324411_2325623_+|MFS-transporter	gnl|CDD|341042	cd17489, MFS_YfcJ_like, Escherichia coli YfcJ, YhhS, and similar transporters of the Major Facilitator Superfamily. This subfamily is composed of Escherichia coli membrane proteins, YfcJ and YhhS, Bacillus subtilis uncharacterized MFS-type transporter YwoG, and similar proteins. YfcJ and YhhS are putative arabinose efflux transporters. YhhS has been implicated glyphosate resistance. YfcJ-like arabinose efflux transporters belong to the bacterial MdtG-like and eukaryotic solute carrier 18 (SLC18) family of the Major Facilitator Superfamily (MFS) of transporters. MFS proteins are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	5.92881e-73
NC_002745.2|WP_000866971.1|2328299_2328533_-|molybdopterin-converting-factor-subunit-1	gnl|CDD|340452	cd00754, Ubl_MoaD, ubiquitin-like (Ubl) domain found in molybdenum cofactor biosynthesis protein D (MoaD) and similar proteins. MoaD, also termed molybdopterin synthase sulfur carrier subunit, or MPT synthase subunit 1, or MPT synthase small subunit, or molybdopterin-converting factor small subunit, or molybdopterin-converting factor subunit 1, is a conserved small sulfur carrier protein that has beta-grasp ubiquitin-like (Ubl) fold involved in biosynthesis of the molybdenum cofactor (Moco), an essential cofactor of a diverse group of redox enzymes. MoaD is activated in an ATP-dependent manner by sulfurtransferases similar to the activation mechanism of ubiquitin-activating enzyme E1.	8.16473e-25
NC_002745.2|WP_000076930.1|2331835_2332840_-|ThiF-family-adenylyltransferase	gnl|CDD|181084	PRK07688, PRK07688, thiamine/molybdopterin biosynthesis ThiF/MoeB-like protein; Validated.	6.83722e-133
NC_002745.2|WP_000808495.1|2328538_2328985_-|molybdenum-cofactor-biosynthesis-protein-MoaE	gnl|CDD|223391	COG0314, MoaE, Molybdopterin converting factor, large subunit [Coenzyme metabolism].	6.99133e-58
NC_002745.2|WP_000259717.1|2329480_2330740_-|molybdopterin-molybdotransferase-MoeA	gnl|CDD|238452	cd00887, MoeA, MoeA family. Members of this family are involved in biosynthesis of the molybdenum cofactor (MoCF), an essential cofactor of a diverse group of redox enzymes. MoCF biosynthesis is an evolutionarily conserved pathway present in eubacteria, archaea and eukaryotes. MoCF contains a tricyclic pyranopterin, termed molybdopterin (MPT). MoeA, together with MoaB, is responsible for the metal incorporation into MPT, the third step in MoCF biosynthesis. The plant homolog Cnx1 is a MoeA-MogA fusion protein. The mammalian homolog gephyrin is a MogA-MoeA fusion protein, that plays a critical role in postsynaptic anchoring of inhibitory glycine receptors and major GABAa receptor subtypes.	4.50966e-159
NC_002745.2|WP_000134526.1|2330802_2331297_+|cyclic-pyranopterin-monophosphate-synthase-MoaC	gnl|CDD|236483	PRK09364, moaC, cyclic pyranopterin monophosphate synthase MoaC.	2.93711e-97
NC_002745.2|WP_000066900.1|2325724_2326075_-|HTH-type-transcriptional-regulator-SarV	gnl|CDD|130944	TIGR01889, Pleiotropic_Regulator_Of_Virulence, staphylococcal accessory regulator family. This model represents a family of transcriptional regulatory proteins in Staphylococcus aureus and Staphylococcus epidermidis. Some members contain two tandem copies of this region. This family is related to the MarR transcriptional regulator family described by pfam01047. [Regulatory functions, DNA interactions].	2.64009e-20
NC_002745.2|WP_000413862.1|2321155_2322421_-|lipid-II:glycine-glycyltransferase-FemX	gnl|CDD|225224	COG2348, COG2348, Peptidoglycan interpeptide bridge formation enzyme [Cell wall/membrane/envelope biogenesis].	1.81413e-143
NC_002745.2|WP_000602950.1|2328998_2329484_-|molybdopterin-guanine-dinucleotide-biosynthesis-protein-B	gnl|CDD|224677	COG1763, MobB, Molybdopterin-guanine dinucleotide biosynthesis protein [Coenzyme metabolism].	9.59347e-51
NC_002745.2|WP_000592307.1|2317871_2321039_-|efflux-RND-transporter-permease-subunit	gnl|CDD|223911	COG0841, AcrB, Cation/multidrug efflux pump [Defense mechanisms].	0

Protein sequences

>NC_002745.2|WP_001792132.1|2326200_2326386_+|hypothetical-protein
MFRFISFGQLVVYSTTFIPKKDILQLNDLECDINVKEPLKINYVVIFGSGTEITFSQNLFR
>NC_002745.2|WP_000066900.1|2325724_2326075_-|HTH-type-transcriptional-regulator-SarV
MSNKVQRFIEAERELSQLKHWLKTTHKISIEEFVVLFKVYEAEKISGKELRDTLHFEMLWDTSKIDVIIRKIYKKELISKLRSETDERQVFYFYSTSQKKLLDKITKEIEVLSVTN
>NC_002745.2|WP_000184404.1|2324411_2325623_+|MFS-transporter
MTNQGSLNKSPIFTKSFTINFFVNFIVYLCMYLLLVVIAGYSKQAFDASDSLAGLVVGLFIVGSLIGRFATGKFVNQIGPKRLLFIGLIALIITQLLYFIDGSLAFLIFVRLINGIATAVVTTATGTIAAYVTPVNRKSEGISLFSLSLVLGTAIGPFLGMLLITKYAIDLLFIICVILGILGLIISLFIKVDFEVTNNKTETDVINKPRFSIHQFIAKEAIPVAVIMLLIGVTYASILTYLQAFALERHLVTAASYFFICYAIASLITRPIAGRLMDDKNENIIVYPAFIMLFLSFVCLISSYQSWLILLAGACLGLGYGNLSSAMQSIAIKVSPPIKYGIATSTFYVGLDAGVGFGPSFLGLFTHMFSYSEIFGFMAALAIITMLVYFLIHGRHVTRNAMN
>NC_002745.2|WP_000951058.1|2323978_2324419_+|winged-helix-DNA-binding-protein
MLSQEFFNSFITIYRPYLKLAEPILEKHNIYYGQWLILRDIAKHQPTTLIEISHRRAIEKPTARKTLKALIENDLITVENSLEDKRQKFLTLTPKGHELYEIVCLDVQKLQQAVVAKTNISQDQMQETINVMNQIHEILLKEAHND
>NC_002745.2|WP_000600967.1|2323052_2323817_-|VOC-family-protein
MILKFDHIIHYIDQLDRFSFPGDVIKLHSGGYHHKYGTFNKLGYINENYIELLDVENNEKLKKMAKTIEGGVAFATQIVQEKYEQGFKNICLRTNDIEAVKNKLQSEQVEVVGPIQMERDTHKDGKVKWQLLYIMNQDDDEIKPPFFIQWEESDSMRTKKLQKYFQKQFSIETVIVKSKNRSQTVSNWLKWFDMDIVEENDHYTDLILKNDDIYFRIEDGKVSKYHSVIIKDAQATSPYSIFIRGAIYRFEPLV
>NC_002745.2|WP_001549681.1|2322809_2323061_+|hypothetical-protein
MRTIILSLFIIMNIVAIIMTLSQPLTVNYFSLRVILIFFTFILSIFFILIKSSRLNNILTILSIVLVIIHMGILAHSTYVYLY
>NC_002745.2|WP_000413862.1|2321155_2322421_-|lipid-II:glycine-glycyltransferase-FemX
MEKMHITNQEHDAFVKSHPNGDLLQLTKWAETKKLTGWYARRIAVGRDGEVQGVAQLLFKKVPKLPYTLCYISRGFVVDYSNKEALNALLDSAKEIAKAEKAYAIKIDPDVEVDKGTDALQNLKALGFKHKGFKEGLSKDYIQPRMTMITPIDKNDDELLNSFERRNRSKVRLALKRGTTVERSDREGLKTFAELMKITGERDGFLTRDISYFENIYDALHEDGDAELFLVKLDPKENIAKVNQELNELHAEIAKWQQKMETSEKQAKKAQNMINDAQNKIAKNEDLKRDLEALEKEHPEGIYLSGALLMFAGSKSYYLYGASSNEFRDFLPNHHMQYTMMKYAREHGATTYDFGGTDNDPDKDSEHYGLWAFKKVWGTYLSEKIGEFDYILNQPLYQLIEQVKPRLTKAKIKISRKLKRK
>NC_002745.2|WP_000592307.1|2317871_2321039_-|efflux-RND-transporter-permease-subunit
MIKKLLQFSLGNKFAIFLMVVLVVLGGVYASAKLKLELLPNVQNPVISVTTTMPGATPQSTQDEISSKIDNQVRSLAYVKNVKTQSIQNASIVTVEYENNTDMDKAEEQLKKEIDKIKFKDEVGQPELRRNSMDAFPVLAYSFSNKENDLKKVTKVLNEQLIPKLQTVDGVQNAQLNGQTNREITLKFKQNELEKYGLTADDVENYLKTATRTTPLGLFQFGDKDKSIVVDGQYQSVDAFKNINIPLTLAGGQGQSQSQSDNKQNSAMSDVNQASPQQNSKASAPNNISGMPTAKLGDLADITVGDVRTSISKTNGKDAVNLQITKAQDANTVQVAKDVQRKIDTFVDENKDFNVTKTMDTAKPVEKSLYTMVEKASLGTIVAIIVILLFLRNIRTTAISIISIPLSLLMALIALKLSDVSLNILTLGALTVAIGRVIDDSIVVVENIYRRLTDSEEQLKGENLIISATTEVFKPIMSSTLVTIIVFLPLVFVSGSVGEMFRPFALAIAFSLLASLLVSITLVPALAATLFKKGVKRRNKQHQEGLGVVSTTYKKVLHWSLNHKWIVIILSTLILVATIVFGGPRLGTSFISAGDDKFLAITYTPKPGETEQAVLNHAKDVEKYLKQKKHVKTIQYSVGGSSPVDPTGSTNSMAIMVEYDNDTPNFDVEADKVIKHVDGFKHPGEWKNQDLGTGAGNKSVEVTVKGPSMDAIKSTVKDIEQKMKQVKGLANVKSDLSQTYDQYEIKVDQNKAAENGISASQLAMHLNENLPEKTVTTVKENGKTVDVKVKQNKQTDWSEDKLNNITLKKPTGGTIKLGDIATLVKTTTPSKLTQEQGDYATTVSAKVTNKDVGGTTRQVMSKINNLDKPNNVKVNIGGASDDINNAMTQLAFAMLAAIIIVYLILVITFKGGLAPFTILFSLPFTVIGVIIALLITGETISVPSLIGMLMLIGIVVTNAIVLIDRVINNEQQGMEMKEALIEAGGTRIRPILMTAIATIGALVPLLFGQDSSILISKGLAATVIGGLISSTLLTLVVVPVIYEILFTLKKRFTKR
>NC_002745.2|WP_001161085.1|2317370_2317688_+|hypothetical-protein
MQFYLILLAILYLIVSFISIFKMEVVFTRILRIIMGVLLLFVLALTTMSFPKENWWVFIVLLLLVGNVEVTGFKMLKKDLKGVNILNLMSLFIFVIYFILTIVLF
>NC_002745.2|WP_000051210.1|2316961_2317126_+|hypothetical-protein
MSLENQLAELKYDYVRLQGDLEKRESLNLDTSALVRQLKDIENEIRNVRAQMQD
>NC_002745.2|WP_000230173.1|2326651_2327674_-|GTP-3',8-cyclase-MoaA
MVEQIKDKLGRPIRDLRLSVTDRCNFRCDYCMPKEVFGDDFVFLPKNELLTFDEMARIAKVYAELGVKKIRITGGEPLMRRDLDVLIAKLNQIDGIEDIGLTTNGLLLKKHGQKLYDAGLRRINVSLDAIDDTLFQSINNRNIKATTILEQIDYATSIGLNVKVNVVIQKGINDDQIIPMLEYFKDKHIEIRFIEFMDVGNDNGWDFSKVVTKDEMLTMIEQHFEIDPVEPKYFGEVAKYYRHKDNGVQFGLITSVSQSFCSTCTRARLSSDGKFYGCLFATVDGFNVKAFIRSGVTDEELKEQFKALWQIRDDRYSDERTAQTVANRQRKKINMNYIGG
>NC_002745.2|WP_000643986.1|2327693_2328293_-|molybdenum-cofactor-guanylyltransferase-MobA
MKAIILAGGHSVRFGKPKAFAEVNGETFYSRVIKTLESTNMFNEIIISTNAQLATQFKYPNVVIDDENHNDKGPLAGIYTIMKQHPEEELFFVVSVDTPMITGKAVSTLYQFLVSHLIENHLDVAAFKEDGRFIPTIAFYSPNALGAITKALHSDNYSFKNIYHELSTDYLDVRDVDAPSYWYKNINYQHDLDALIQKL
>NC_002745.2|WP_000866971.1|2328299_2328533_-|molybdopterin-converting-factor-subunit-1
MKVLYFAEIKDILQKAQEDIVLEQALTVQQFEDLLFERYPQINNKKFQVAVNEEFVQKSDFIQPNDTVALIPPVSGG
>NC_002745.2|WP_000808495.1|2328538_2328985_-|molybdenum-cofactor-biosynthesis-protein-MoaE
MKQFEIVIEPIQTEQYREFTINEYQGAVVVFTGHVREWTKGVKTEYLEYEAYIPMAEKKLAQIGDEINEKWPGTITSIVHRIGPLQISDIAVLIAVSSPHRKDAYRANEYAIERIKEIVPIWKKEIWEDGSKWQGHQKGNYEEAKREE
>NC_002745.2|WP_000602950.1|2328998_2329484_-|molybdopterin-guanine-dinucleotide-biosynthesis-protein-B
MILQIVGYKKSGKTTLMRHIVSFLKTHGYTVATIKHHGHAKEDIQLQDSDVDHMKHFEAGADQSIVQGFQYQQTVTRVDNQNLTQIIEKSVTIDTNIVLVEGFKNADFEKVVVYRDEEELQVLQQLSNVCYSINVREHEDFTAFEQWLLNKIKNDCDTQLT
>NC_002745.2|WP_000259717.1|2329480_2330740_-|molybdopterin-molybdotransferase-MoeA
MVVEKRNPIPVKEAIQRIVNQQSSMPAITVALEKSLNHILAEDIVATYDIPRFDKSPYDGFAIRSVDSQGASGQNRIEFKVIDHIGAGSVSDKLVGDHEAVRIMTGAQIPNGADAVVMFEQTIELEDTFTIRKPFSKNENISLKGEETKTGDVVLKKGQVINPGAIAVLATYGYAEVKVIKQPSVAVIATGSELLDVNDVLEDGKIRNSNGPMIRALAEKLGLEVGIYKTQKDDLDSGIQVVKEAMEKHDIVITTGGVSVGDFDYLPEIYKAVKAEVLFNKVAMRPGSVTTVAFADGKYLFGLSGNPSACFTGFELFVKPAVKHMCGALEVFPQIIKATLMEDFTKANPFTRFIRAKATLTSAGATVVPSGFNKSGAVVAIAHANCMVMLPGGSRGFKAGHTVDIILTESDAAEEELLL
>NC_002745.2|WP_000134526.1|2330802_2331297_+|cyclic-pyranopterin-monophosphate-synthase-MoaC
MTEFTHINQQGHAKMVDVSDKQITKRTAVAHSSITVNETIFKQISNNTNTKGNVLNTAQIAGIMAAKNTSTIIPMCHPLPLTGIDVHFSWDETNAPLYTLNIQTTVSTTGKTGVEMEALTAASATALTIYDMTKAVDKGMIIGETYLESKSGGKSGDFQRQSGQ
>NC_002745.2|WP_000503822.1|2331298_2331805_-|molybdenum-cofactor-biosynthesis-protein-MoaB
MGEHQNVKLNRTVKAAVLTVSDTRDFVTDKGGQCVRQLLQADDVEVSDAHYTIVKDEKVAITTQVKKWLEEDIDVIITTGGTGIAQRDVTIEAVKPLLTKEIEGFGELFRYLSYVEDVGTRALLSRAVAGTVNNKLIFSIPGSTGAVKLALEKLIKPELNHLIHELTK
>NC_002745.2|WP_000076930.1|2331835_2332840_-|ThiF-family-adenylyltransferase
MSQERYSRQILFKQIGEIGQSKINQKCALIIGMGALGTHVAEGLVRAGIAKLIIVDRDYIEFSNLQRQTLFTEEDALKMMPKVVAAKKHLLALRSDVDIDGCIAHVDYYFLETHGQDVDVIIDATDNFETRQLINDFAYKHRIPWIYGGVVQSTYTEAAFIPGKTPCFNCLVPQLPALNLTCDTVGVIQPAVTMATSLQLRDAMKVLTEQPIDTKITYGDIWEGSHYSFGFSKMQRSDCTTCGDVPSYPYLNKNEQRYATLCGRDTVQYENASITHDILVQFLKQHQLNYRSNSYMVMFEFKGHRIVAFKGGRFLIHGMTRTSDATHLMNLLFG
>NC_002745.2|WP_000913024.1|2333009_2333615_-|ATP-binding-cassette-domain-containing-protein
MLKINVKYQLKNTLIRINIDDTEPKIYAVRGPSGIGKTTVLNMIAGLRKADEAIIEVNGQLLTDTTKNVNVKIQQRRIGYLFQDYQLFPNMTVYKNITFMAEPSKHIDQLIQTLNINHLMKQYPMTLSGGEAQRVALARALSTKPDLILLDEPFSSLDDTTKDESITLVKRIFNEWQIPIIFVTHSNYEAEQMAHEIITIG

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity
NC_002745_1	1.1|188453|33|NC_002745|CRISPRCasFinder	188453-188485	33	NC_002745.2	1348825-1348857	0	1.0
NC_002745_4	4.1|818131|31|NC_002745|CRISPRCasFinder	818131-818161	31	NC_002745.2	311624-311654	0	1.0
NC_002745_8	8.1|2054636|34|NC_002745|CRISPRCasFinder	2054636-2054669	34	NC_002745.2	818106-818139	0	1.0
NC_002745_8	8.1|2054636|34|NC_002745|CRISPRCasFinder	2054636-2054669	34	NC_002745.2	1137084-1137117	0	1.0
NC_002745_4	4.1|818131|31|NC_002745|CRISPRCasFinder	818131-818161	31	NC_002745.2	311569-311599	1	0.968
NC_002745_5	5.1|874004|34|NC_002745|CRISPRCasFinder	874004-874037	34	NC_002745.2	1348824-1348857	1	0.971
NC_002745_6	6.1|1618610|33|NC_002745|CRISPRCasFinder	1618610-1618642	33	NC_002745.2	823665-823697	1	0.97
NC_002745_6	6.1|1618610|33|NC_002745|CRISPRCasFinder	1618610-1618642	33	NC_002745.2	823724-823756	1	0.97
NC_002745_6	6.1|1618610|33|NC_002745|CRISPRCasFinder	1618610-1618642	33	NC_002745.2	1348825-1348857	1	0.97
NC_002745_8	8.1|2054636|34|NC_002745|CRISPRCasFinder	2054636-2054669	34	NC_002745.2	1745319-1745352	1	0.971
NC_002745_12	12.1|2326453|31|NC_002745|CRISPRCasFinder	2326453-2326483	31	NC_002745.2	830909-830939	1	0.968
NC_002745_12	12.1|2326453|31|NC_002745|CRISPRCasFinder	2326453-2326483	31	NC_002745.2	830965-830995	1	0.968
NC_002745_12	12.1|2326453|31|NC_002745|CRISPRCasFinder	2326453-2326483	31	NC_002745.2	831021-831051	1	0.968
NC_002745_12	12.1|2326453|31|NC_002745|CRISPRCasFinder	2326453-2326483	31	NC_002745.2	831077-831107	1	0.968
NC_002745_1	1.1|188453|33|NC_002745|CRISPRCasFinder	188453-188485	33	NC_002745.2	823665-823697	2	0.939
NC_002745_1	1.1|188453|33|NC_002745|CRISPRCasFinder	188453-188485	33	NC_002745.2	823724-823756	2	0.939
NC_002745_1	1.1|188453|33|NC_002745|CRISPRCasFinder	188453-188485	33	NC_002745.2	1437091-1437123	2	0.939
NC_002745_7	7.2|1653121|22|NC_002745|PILER-CR	1653121-1653142	22	NC_002745.2	1137206-1137227	2	0.909
NC_002745_7	7.2|1653121|22|NC_002745|PILER-CR	1653121-1653142	22	NC_002745.2	2054581-2054602	2	0.909
NC_002745_7	7.2|1653121|22|NC_002745|PILER-CR	1653121-1653142	22	NC_002745.2	2054698-2054719	2	0.909
NC_002745_8	8.1|2054636|34|NC_002745|CRISPRCasFinder	2054636-2054669	34	NC_002745.2	1353198-1353231	2	0.941
NC_002745_8	8.1|2054636|34|NC_002745|CRISPRCasFinder	2054636-2054669	34	NC_002745.2	2774105-2774138	2	0.941
NC_002745_12	12.1|2326453|31|NC_002745|CRISPRCasFinder	2326453-2326483	31	NC_002745.2	89940-89970	2	0.935
NC_002745_12	12.1|2326453|31|NC_002745|CRISPRCasFinder	2326453-2326483	31	NC_002745.2	387956-387986	2	0.935
NC_002745_12	12.1|2326453|31|NC_002745|CRISPRCasFinder	2326453-2326483	31	NC_002745.2	651750-651780	2	0.935
NC_002745_12	12.1|2326453|31|NC_002745|CRISPRCasFinder	2326453-2326483	31	NC_002745.2	831133-831163	2	0.935
NC_002745_12	12.1|2326453|31|NC_002745|CRISPRCasFinder	2326453-2326483	31	NC_002745.2	874316-874346	2	0.935
NC_002745_12	12.1|2326453|31|NC_002745|CRISPRCasFinder	2326453-2326483	31	NC_002745.2	1040093-1040123	2	0.935
NC_002745_12	12.1|2326453|31|NC_002745|CRISPRCasFinder	2326453-2326483	31	NC_002745.2	1142685-1142715	2	0.935
NC_002745_12	12.1|2326453|31|NC_002745|CRISPRCasFinder	2326453-2326483	31	NC_002745.2	1348783-1348813	2	0.935
NC_002745_12	12.1|2326453|31|NC_002745|CRISPRCasFinder	2326453-2326483	31	NC_002745.2	1437135-1437165	2	0.935
NC_002745_12	12.1|2326453|31|NC_002745|CRISPRCasFinder	2326453-2326483	31	NC_002745.2	1633248-1633278	2	0.935
NC_002745_12	12.1|2326453|31|NC_002745|CRISPRCasFinder	2326453-2326483	31	NC_002745.2	1950741-1950771	2	0.935
NC_002745_12	12.1|2326453|31|NC_002745|CRISPRCasFinder	2326453-2326483	31	NC_002745.2	2315652-2315682	2	0.935
NC_002745_12	12.1|2326453|31|NC_002745|CRISPRCasFinder	2326453-2326483	31	NC_002745.2	2491006-2491036	2	0.935

1. spacer 1.1|188453|33|NC_002745|CRISPRCasFinder matches to position: 1348825-1348857, mismatch: 0, identity: 1.0

tgggccccaacaaagagaaattggattcccaat	CRISPR spacer
tgggccccaacaaagagaaattggattcccaat	Protospacer
*********************************

2. spacer 4.1|818131|31|NC_002745|CRISPRCasFinder matches to position: 311624-311654, mismatch: 0, identity: 1.0

ctgtgttggggccccgccaacttgcattgcc	CRISPR spacer
ctgtgttggggccccgccaacttgcattgcc	Protospacer
*******************************

3. spacer 8.1|2054636|34|NC_002745|CRISPRCasFinder matches to position: 818106-818139, mismatch: 0, identity: 1.0

ttgtagaatttcttttcgaaattctctgtgttgg	CRISPR spacer
ttgtagaatttcttttcgaaattctctgtgttgg	Protospacer
**********************************

4. spacer 8.1|2054636|34|NC_002745|CRISPRCasFinder matches to position: 1137084-1137117, mismatch: 0, identity: 1.0

ttgtagaatttcttttcgaaattctctgtgttgg	CRISPR spacer
ttgtagaatttcttttcgaaattctctgtgttgg	Protospacer
**********************************

5. spacer 4.1|818131|31|NC_002745|CRISPRCasFinder matches to position: 311569-311599, mismatch: 1, identity: 0.968

ctgtgttggggccccgccaacttgcattgcc	CRISPR spacer
ctgtgttggggccccgccaacttgcattacc	Protospacer
****************************.**

6. spacer 5.1|874004|34|NC_002745|CRISPRCasFinder matches to position: 1348824-1348857, mismatch: 1, identity: 0.971

attgagaatccaatttctctttgttggggcccat	CRISPR spacer
attgggaatccaatttctctttgttggggcccat	Protospacer
****.*****************************

7. spacer 6.1|1618610|33|NC_002745|CRISPRCasFinder matches to position: 823665-823697, mismatch: 1, identity: 0.97

attgggaatccaatttctctgtgttggggccca	CRISPR spacer
attggaaatccaatttctctgtgttggggccca	Protospacer
*****.***************************

8. spacer 6.1|1618610|33|NC_002745|CRISPRCasFinder matches to position: 823724-823756, mismatch: 1, identity: 0.97

attgggaatccaatttctctgtgttggggccca	CRISPR spacer
attggaaatccaatttctctgtgttggggccca	Protospacer
*****.***************************

9. spacer 6.1|1618610|33|NC_002745|CRISPRCasFinder matches to position: 1348825-1348857, mismatch: 1, identity: 0.97

attgggaatccaatttctctgtgttggggccca	CRISPR spacer
attgggaatccaatttctctttgttggggccca	Protospacer
******************** ************

10. spacer 8.1|2054636|34|NC_002745|CRISPRCasFinder matches to position: 1745319-1745352, mismatch: 1, identity: 0.971

ttgtagaatttcttttcgaaattctctgtgttgg	CRISPR spacer
ttgtagaatttcttttcgaaattctttgtgttgg	Protospacer
*************************.********

11. spacer 12.1|2326453|31|NC_002745|CRISPRCasFinder matches to position: 830909-830939, mismatch: 1, identity: 0.968

cacattattgtaagctgactttctgtcagct	CRISPR spacer
cacattattgtaagctgactttccgtcagct	Protospacer
***********************.*******

12. spacer 12.1|2326453|31|NC_002745|CRISPRCasFinder matches to position: 830965-830995, mismatch: 1, identity: 0.968

cacattattgtaagctgactttctgtcagct	CRISPR spacer
cacattattgtaagctgactttccgtcagct	Protospacer
***********************.*******

13. spacer 12.1|2326453|31|NC_002745|CRISPRCasFinder matches to position: 831021-831051, mismatch: 1, identity: 0.968

cacattattgtaagctgactttctgtcagct	CRISPR spacer
cacattattgtaagctgactttccgtcagct	Protospacer
***********************.*******

14. spacer 12.1|2326453|31|NC_002745|CRISPRCasFinder matches to position: 831077-831107, mismatch: 1, identity: 0.968

cacattattgtaagctgactttctgtcagct	CRISPR spacer
cacattattgtaagctgactttccgtcagct	Protospacer
***********************.*******

15. spacer 1.1|188453|33|NC_002745|CRISPRCasFinder matches to position: 823665-823697, mismatch: 2, identity: 0.939

tgggccccaacaaagagaaattggattcccaat	CRISPR spacer
tgggccccaacacagagaaattggatttccaat	Protospacer
************ **************.*****

16. spacer 1.1|188453|33|NC_002745|CRISPRCasFinder matches to position: 823724-823756, mismatch: 2, identity: 0.939

tgggccccaacaaagagaaattggattcccaat	CRISPR spacer
tgggccccaacacagagaaattggatttccaat	Protospacer
************ **************.*****

17. spacer 1.1|188453|33|NC_002745|CRISPRCasFinder matches to position: 1437091-1437123, mismatch: 2, identity: 0.939

tgggccccaacaaagagaaattggattcccaat	CRISPR spacer
tggaccccaacaaagagaaattgtattcccaat	Protospacer
***.******************* *********

18. spacer 7.2|1653121|22|NC_002745|PILER-CR matches to position: 1137206-1137227, mismatch: 2, identity: 0.909

tgaaattggggttccaatttct	CRISPR spacer
tgaaattggtgatccaatttct	Protospacer
********* * **********

19. spacer 7.2|1653121|22|NC_002745|PILER-CR matches to position: 2054581-2054602, mismatch: 2, identity: 0.909

tgaaattggggttccaatttct	CRISPR spacer
tgaaattgggaatccaatttct	Protospacer
**********. **********

20. spacer 7.2|1653121|22|NC_002745|PILER-CR matches to position: 2054698-2054719, mismatch: 2, identity: 0.909

tgaaattggggttccaatttct	CRISPR spacer
tgaaattgggaatccaatttct	Protospacer
**********. **********

21. spacer 8.1|2054636|34|NC_002745|CRISPRCasFinder matches to position: 1353198-1353231, mismatch: 2, identity: 0.941

ttgtagaatttcttttcgaaattctctgtgttgg	CRISPR spacer
ttgtggaatttcttatcgaaattctctgtgttgg	Protospacer
****.********* *******************

22. spacer 8.1|2054636|34|NC_002745|CRISPRCasFinder matches to position: 2774105-2774138, mismatch: 2, identity: 0.941

ttgtagaatttcttttcgaaattctctgtgttgg	CRISPR spacer
ttgtagaatttcttttcgaaattctttttgttgg	Protospacer
*************************.* ******

23. spacer 12.1|2326453|31|NC_002745|CRISPRCasFinder matches to position: 89940-89970, mismatch: 2, identity: 0.935

cacattattgtaagctgactttctgtcagct	CRISPR spacer
cacattattgtaagctgactttccgccagct	Protospacer
***********************.*.*****

24. spacer 12.1|2326453|31|NC_002745|CRISPRCasFinder matches to position: 387956-387986, mismatch: 2, identity: 0.935

cacattattgtaagctgactttctgtcagct	CRISPR spacer
cacattattgtaagctgacttttcgtcagct	Protospacer
**********************..*******

25. spacer 12.1|2326453|31|NC_002745|CRISPRCasFinder matches to position: 651750-651780, mismatch: 2, identity: 0.935

cacattattgtaagctgactttctgtcagct	CRISPR spacer
cacattattgtaagctgacttttcgtcagct	Protospacer
**********************..*******

26. spacer 12.1|2326453|31|NC_002745|CRISPRCasFinder matches to position: 831133-831163, mismatch: 2, identity: 0.935

cacattattgtaagctgactttctgtcagct	CRISPR spacer
cacattattgtaagctgactttccgccagct	Protospacer
***********************.*.*****

27. spacer 12.1|2326453|31|NC_002745|CRISPRCasFinder matches to position: 874316-874346, mismatch: 2, identity: 0.935

cacattattgtaagctgactttctgtcagct	CRISPR spacer
cacattattgtaagctgactttccgccagct	Protospacer
***********************.*.*****

28. spacer 12.1|2326453|31|NC_002745|CRISPRCasFinder matches to position: 1040093-1040123, mismatch: 2, identity: 0.935

cacattattgtaagctgactttctgtcagct	CRISPR spacer
cacattattgtaagctgacttttcgtcagct	Protospacer
**********************..*******

29. spacer 12.1|2326453|31|NC_002745|CRISPRCasFinder matches to position: 1142685-1142715, mismatch: 2, identity: 0.935

cacattattgtaagctgactttctgtcagct	CRISPR spacer
cacattattgtaagctgacttttcgtcagct	Protospacer
**********************..*******

30. spacer 12.1|2326453|31|NC_002745|CRISPRCasFinder matches to position: 1348783-1348813, mismatch: 2, identity: 0.935

cacattattgtaagctgactttctgtcagct	CRISPR spacer
cacattattgtaagctgacttttcgtcagct	Protospacer
**********************..*******

31. spacer 12.1|2326453|31|NC_002745|CRISPRCasFinder matches to position: 1437135-1437165, mismatch: 2, identity: 0.935

cacattattgtaagctgactttctgtcagct	CRISPR spacer
cacattattgtaagctgacttttcgtcagct	Protospacer
**********************..*******

32. spacer 12.1|2326453|31|NC_002745|CRISPRCasFinder matches to position: 1633248-1633278, mismatch: 2, identity: 0.935

cacattattgtaagctgactttctgtcagct	CRISPR spacer
cacattattgtaagctgactttccgccagct	Protospacer
***********************.*.*****

33. spacer 12.1|2326453|31|NC_002745|CRISPRCasFinder matches to position: 1950741-1950771, mismatch: 2, identity: 0.935

cacattattgtaagctgactttctgtcagct	CRISPR spacer
cacattattgtaagctgacttttcgtcagct	Protospacer
**********************..*******

34. spacer 12.1|2326453|31|NC_002745|CRISPRCasFinder matches to position: 2315652-2315682, mismatch: 2, identity: 0.935

cacattattgtaagctgactttctgtcagct	CRISPR spacer
cacattattgtaagctgacttttcgtcagct	Protospacer
**********************..*******

35. spacer 12.1|2326453|31|NC_002745|CRISPRCasFinder matches to position: 2491006-2491036, mismatch: 2, identity: 0.935

cacattattgtaagctgactttctgtcagct	CRISPR spacer
cacattattgtaagctgactttccgccagct	Protospacer
***********************.*.*****

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NC_002745_11	11.1|2218475|34|NC_002745|CRISPRCasFinder	2218475-2218508	34	JN882286	Cronobacter phage vB_CsaP_GAP52, complete genome	23034-23067	8	0.765
NC_002745_11	11.1|2218475|34|NC_002745|CRISPRCasFinder	2218475-2218508	34	CP030544	Staphylococcus aureus strain ER04166.3 plasmid unnamed2, complete sequence	7567-7600	8	0.765

1. spacer 11.1|2218475|34|NC_002745|CRISPRCasFinder matches to JN882286 (Cronobacter phage vB_CsaP_GAP52, complete genome) position: , mismatch: 8, identity: 0.765

ttgcatatctttagctttattgtttgcaactggg	CRISPR spacer
ttgcatatctttagctttatagcttttatatgct	Protospacer
******************** *.** .*  **  

2. spacer 11.1|2218475|34|NC_002745|CRISPRCasFinder matches to CP030544 (Staphylococcus aureus strain ER04166.3 plasmid unnamed2, complete sequence) position: , mismatch: 8, identity: 0.765

ttgcatatctttagctttattgtttgcaactggg	CRISPR spacer
ttgaataactttagctttattgttataaacagta	Protospacer
*** *** ****************   *** * .

Prophage detection

Region	Region Position	Protein_number	Hit_taxonomy	Key_proteins	Att_site
DBSCAN-SWA_1	755279 : 763100	10	Hokovirus(16.67%)	NA	NA
DBSCAN-SWA_2	775071 : 789712	14	uncultured_Caudovirales_phage(50.0%)	NA	NA
DBSCAN-SWA_3	1668253 : 1677296	7	uncultured_Mediterranean_phage(50.0%)	tRNA	NA
DBSCAN-SWA_4	1808959 : 1866661	54	Staphylococcus_phage(95.35%)	tRNA,protease	NA
DBSCAN-SWA_5	1976120 : 2074317	126	Staphylococcus_phage(86.96%)	head,holin,terminase,coat,capsid,tail,portal,protease,integrase	attL 2056679:2056699|attR 2072338:2072358

Sequences of DBSCAN-SWA_1

Nucleotide sequences of DBSCAN-SWA_1

>NC_002745|755279:763100|DBSCAN-SWA
ATTATGACGTAATGTCTAATTTGTGTAATGTTACAGTCATCGTAGTTCCTACATCTATATCACTGCTTACACTGATTTTTGCGTTATTTTGTTGCGCGAGTTCATTAGCTATATATAAGCCTAATCCAGAACCACCCGTTTTTGTATTACGAGAGTTTTCTACTCTGAATGTACGTTCGAATATACGTTCTTGTAGTTCTGGTATAATGCCAATACCTTCATCGCTAATAGCAATGTCGATAGTATCTTGATCTTTGTTTTCACTAATATTAATATCAATGCGACTACCAACATTTGAAAATTTTAGCGCATTATCAAGTAAGTTTGTTAAAATACGCTCAAGTGGCGTTCGATATTGATAAAATGCATCAATTTCGCTACAGAAATTCACTTCTAATGTGCGGTTTTCATGTTTGATACGTTGCTCATATGGTTGCAATATTGATACAAGTAATTGGTCTAGTTGTATTAATTCTGGGGGATATGTTTTACCTGTATTTAAAGTGATAATATGAGTCATATCATCAAATAATGTTGATAATCTGTTTGCTTGTTTAATTAATATGTCGTATGACTCTTTAATCTCATGATCCTTTGTGATTATACCATCACGTAGTCCTTCAGAATATGAAATAATGCTTGCTAAAGGTGTTTTTAAATCATGGGCTAAGTTTTGAATCAGTTCTGTTTTTTCTTGTTGTTCGGATTTAATTTGATTCATTTGTTGCGTAATTTCAGAAGCCATTTTATTAAAAGATTGATTTAATTCATAAATTTCTTTTGGTGAATTAAACGTTTTATCATTGCTTGCGTAATTTCCGTTAGCAAATTGCTTAGTTTTTATATTAAACTGCTTAATTTTTTGTATAAGTGGATTAATAAAAATACTACATATTAATAAGGTTAAACAGCTTGTAATTATTGTCGTTAAGGTCAAAGTTAGTGTCATATGGCCGTTAAACCACATTAAAATATATGCAATTGCTAAAATAGTTGAAGTTAATAGTATACTCGAAACGACGCCAATAATGATTTGACTTCTAATTGATAACACCATTATCGGCTCCTTTCAAATTTATATCCTAATCCCCATACAGTTGTGATGGTATATGTTGTAAAGCTCTCTTTTTCTAATTTTTCTCTAATACGGTGTATATGGACATTCACGGTATTAGCATCTTCGTAATAGTCATATCCCCAAACTTTTTCAAGTAATTCTGATTTAGAAATAACTTCATTTTCTCTAGAAGCTAAATACCACAATAACTCAAATTCCTTAATACGCATAGGGACTTCGTGACCATTTACAGTCACAACTTTACTTAAGTTAATAAGTGTTAATTCATCAAACGACAGTTGTTCAACTGGTTGATGATGGTATTTCTTCATTCTTGTAAGTAAATTATTAATACGTAAAACGAGTTCCCTTGGACTAAATGGTTTTTTGACATAGTCATCTGCACCTAAAGTTAAGGCGTAAATGGTATCATGTTCTTGTGTTTTGGCAGTTAAATAGATAAAGGGGATATCTAATTTTTGCCTTTTCATTTCTTTGACAATGTCGTAACCATTAACTTCTGGCATCATGATATCAAGTACCATGATATCAATATCATTTGATAGTAAAGAAATTGCTTCTTTACCGCTAGTTGTCGTTGTTACTTTGTAACCTTCATATTCAAAATAGGTTTGACAAATGTCTACAATGTCTTGTTCATCATCCACGATCAGTAAGTGGGTCATCTATTTTTTCACCTCTGTTCTTACGACCTCTAAAGTAATTAATGATTTCTTTAAGTGAAATCTGTTTTAACAATGAGTGACTCATTAGTAAAAGGATAAAGAAAGTTAATTGAAGAGGATACGTAAATATCATATCTGCTAAGATATAATTTATCATAACAAAGGCTCCAAAGAAACTAGCAGCATATGCAAAAACTCCAAAAATTAAACCTAATCCAATTGCAATCTCTCCAAGTGGGACAACAATATCAAATAATGACGTCGTATGTGCAACTATATTTGCGAAAAACCACTTATACCACTCTGGTGAATCAGTATTGTTAGCGATGACTGGTACTAAACCTTTCAGCGTAAATCCGCCCGTTAATTTTTCGTAGCCTTGCATTAACATAACAATACCTGAACCCACACGAATGATAAATGTAACGAGTAGCAATAATTTATTCATGATGTTCACATTCTTTCTATTTATTGTGTGTAATTTATATAAACATAAGATTAAGCAACATAATGCGATTTGTAGTGTTATGTGAACAGGAAGTGTTTGAGCTCATGGGTTGCTTAAGCTAAACAAACCTCAAGCTCTAAAAAAATTTTACTTATGTGCTCTACAATCTTATGGGATTTAATAGTTGTATATATATTGAAAAAAGGAAAGTATGATTTCTACAAGCTAGGGGGGCTGTGAAATCATACGCTTTCCATTGAGTAATGAGTGTAATGTATATTTTTAAAATTTGTAATGTATAGTAATAGTATGTTGTATATAAAAGTTTAACTCAGAAATTGATTATTTTAATTTAGCGCCGCCGAAGATGACGTGAGCTTTTTTACAATAGATTGTTACTTCATCATATTTGCTTAAATCTACATTTTTAAGATCAAATGTTTGTTTTTCTTTATCGTAGTCAACCATTGCGATTTCTTTACCGTTTTTAATGTCGCCATTTTTTGTTAGGTAGACGTATAAATCTGGACCTTTTGATGATTTGTAGTTAGTAAGCATTAATTTACCATTTTTAATCTCAGCTTTACCTTCAACAGTTTCACCGTTTTTAGAACTGAATGTACCTGTTAGGTGTTTTGTTTTATCAGTTTTAACATTGCTATCTTCTGACTTTGTTTTTTGTTCAGTTTTGTTACCTTGATCTTGTGAATTAGAATTACCACAAGCGCCTAAAGTTAATACAGAGGCAACAGCACCAACTGCTAAAAAATATTTTGTATTCATGCTAACTCCTCATTTCTTCAATTTGATAAGTTAAGTTTAAAATGAAGGCAAATAATATGCCATTAACTAATTCTTAACTTCGTTTAAATATCGCTTAACTAATATTGAAGAAAGAATAATTTGAAAATGAAAATAATTGTCTGATTTAAATAAATAGGAGTCAAAATAAGAGGAGGGCATTTTTTTAGGTGAGAAAATATTTATCTGAACTAGATAACACTATAAAACACTTCTGATATTTTGAACTAAGAATATCAGAAGTGTTTTATAGTTTTGGTATTAAAATTTATAAACCTTTTGCCACAATAAAAACAACAAGAAAATAAGATAGACGATTAAATACAAGTACCAATATGGTGTTAAAACCATCATAACGATAAATGAAATGTTAATAATGATAAGTCCTTTAATCATTAGTTTCTTTATTTTGTTATTATTTTCAGCAGTTTCATCTAAGCTATTAAATGTTGAAATAAACAACATAATACCACCAATGATGAAAATTGCAGGGGCTAAAAATGGAATAGACATATATATTGATTGTGTACTTGAAAAGTCGGTAACACGTTGCGTTAAACTGACAACAATCGTTAATATGATAGCAATAAATTTTTGGTCTGTAATGTATACAGGTTTTAATTTTTTATCAATGTAAAACTGTAGTATCGTCCAAATGATAAACATCGTTATAGTACACAGAGTAATAAAGTTATATTTATCAATTATGAATGTATTTATAAAGGCGTTTATCGTAATAGATAACAACATTGCACTTAATGATAAATGTTGCATTTGATGCCTATATAAATTGAATCCAGTTATAAGTACGACGATAGCAATATTAATTAATATATATAAAATCATGATGGACTCCTGTTCGTTATACTTCAATCAACTATTATATCAATTAATATATTGTTATTCATTAGATATGACTTGTAAAAAGTAAAATAAGTTATCCTTTATACACCTTTTTTATTACTCCAAAGTAATGTATGAAGTTGTGGTAACACATAAACGTGATTCATATCATTACTTTGCATAACTAAATCCACCAACTGCTCGTAGCGTTCTAACAACTTTTCGGTATGATTATCTACGCTGTCTGATAAATATGGGTTACCAACTTGTAAATAGAAGGGAATATCTGGATAACGGTGGTGTATCATTTTGGCAAAATCATAATCTTTATCGTCGAATACAACTACTTTTAAGTTTAATGAGGAAGGTACGCATTGTGTAATCACTTCATCTAACTTTTTTAAATCAGGTGTCATAGTTGAACTTGGTGGTTTTGGACTAATCGTTAAATCATCAATTTGTGTCATCCAAGGTTGGAATTTACTGCCTTGTGTCTCCAGTGCGCTGAAAATACCTTTATCTTGAAATAAGTCAACTAACTCTTGGATACCTTTAATTAATGCTGGGTTACCACCAGAAATTGTAACGTGATTAAATAAATCGCCACCAATTCGTTTTAATTCATCATAAATTTCTTCAGCGGTCATGAGTTTTATATCGCCTTTAGCACTACCATCCCAAGTAAATGCAGAATCACACCAGCTACAGCGATAATCACATCCAGCTGTTCTCACAAACATCGTTTTTCTACCGATTACTCGACCTTCACCCTGAATGGTTGGACCGAATATTTCGAGTACAGGAATTTTAGCCATTAGTTACACCTGTTCCTTTGGTCTAAATACAACATAACTTGTTGGTGTTTCTCTTACAAATACTTGAATACATTTTGGTTGGTGTTCGAGCGATGCCAAATTTTCTTTAACAATTTGATAAATTGTTTCCGCTACGATTTCAGTTGAAGGGATTTTGTTTTTAAAAGCAGGTAAGTTATTTAACAGTTGATGGTCAAATTTACCGTGTATCATCTTTTTCAAATGGCTAAAGTTCACTAAGAAGCCAGTGTCATCTAGTTTATCACCGACAATTGTTAAATTAACAAAGTAAGTATGACCATGGACATTTTGACAAATACCTGCTTCTTCACAAGGAATGTGATGTGCAGCCGAAAAATTAAAATCTTTATTTAATTCGAATTGATATGGATGCGTTGTACTAGGATAGATTTGTTGTAACATTTTAAAGCGCTCCTTTACTTTCAAGATATTGATTTAGTCCACGTTGACGTAAATGACAAGCTGGACATTCACCACAGCCATCCCCAATGATACCGTTATAGCATGTTAATGTTTTTGTACGAATATAATCTAAAACTTCGAGTTCATCACTTAATTTCCACGTTTCTGCTTTGTTTAACCACATTAAAGGAGTATGAATGACAAAATCTTTGTCCATAGCTAGGCTTAATGTTACGTTCATTGATTTTATAAAACTATCGCGACAGTCTGGGTAGCCTGAAAAGTCTGTTTCACATACGCCTGTAATAATATGCTTAGCCCCAATTTGATAAGCTAGAGCGCCTGCAAACGACAAGAAAAGTAAATTTCTAGCTGGAACAAATGTATTAGGTATACCATCTTCATTATTAGTAATTTCCATATCATGTTGTGTTAATGCGTTTGGAGTAAGTTGTGATAATAATGACATATCTAAAACGTGATGTTTCATTCCTTGATCTTGTGCAATTTGTTTTGCGACTTCAATTTCAGTATCATGTCTTTGGCCATAATTAAACGTTACGAGTTCAACTTCTTTGAAATGTTTTTTTGCATAAAAGAGACATGTTGTACTGTCTTGACCACCACTAAAGACAACGATGGCTTTTTCATTATTTAATACACTTTCCATTTTGTAATTGCTCCTATCATTAATAATATTAATAAAGAGGTTAATGGCATTGATAAGCCCGTTTTTAATTTATAAAATAAAAAAAGCCTATCTCCATAAAAGATAGACGAAAGAAATGGGTTGCTCCTATAATATATATTAAAGGTTTACCAACGAATGTTTGAAATTTCAATGTCTAGTTTTTTATAGAGGGTTTCAGCTAGAAACCTCTGATATTCATTTATGTACGATGAATAGAATATACCATATATTAGTTAAAATCAAGGTCAGGATAATGACAATGCTTTTAAAGTTTTAGCTACATCCAATACATATTATAAAAATAAAACACATTTAGAACGGAGTATACAATGATTCTAGTCATAGATAATAATGATTCATTTACATATAATTTAATAGACTATATTAAGACTCAAACGAAACTAACAGTTCAAGTTGTTGGTATTGATAATCTGCTGATAGAAGACGTCATTAATATGAAGCCAAAAGCAATTGTTATTTCGCCTGGGCCGGGTAATCCGGATGATTATCCTATCTTGAATGAAGTGTTAGAACAATTTTATCAGCGTGTACCTATACTAGGTGTATGTTTAGGATTTCAATGTATCGTGTCTTATTTTGGTGGAAATATCATTCACGGCTATCATCCTGTACACGGACATACTACACAGTTACGCCATACCAATGAAGGTATTTTTCAAGGACTGCCTCAAAATTTCAATGTAATGCGTTATCATTCATTAATTGCTGACGGAGCGACTTTTCCAAATTGCTTAAAGATTACAGCAAAAAACGATGAAGCGATTATTATGGCATTTGAGCATATTAGATTTCCGGTTTTTGGTGTGCAATATCATCCTGAATCTATTTTGAGTGAATACGGTTATCGACAAGTTGAATTATTTTTATCGAAGGTAGGTGATTACTGTGAGAATAGAATATAATTATCGCTACTATTTAACTGAAAATGAATATAAGCAATACCATATTCAATTAAAGGGATTTATAAAGAAGTATGTTGCTACTAAGTTGGCTGATGTGGGAGAAGTGATACACTTTGCACAAGCGCAGCAACGACAAGGTAGATATGTCTCGTTATATTTAAGTTACGAAGCGGCAAAGTATTTTAATCATGTTATGTGTACACATTCATTAGCTAAAGATGATATTTATGCAGTAGCTTATAGTTTTGAAAAAGCGGAAAGCATAAATTCAACATATGAACATCAAACTTCTTATGTATCAAAGCATCATTTTTCATTTGTTGAATCTTCTGAGGTTATGATGACTAATATTAAACGTGTCCAACAAGCAATTGTTGAAGGTGAAACGTATCAAGTGAACTATACGGCGCGCTTAACGGATAACATTTATTATCCTATTAGTACTTTATATGAACGATTAACTCAATTTAGTAATGGTAATTATACTGCGTTATTACAAACTGATGAAATCCAAGTAGCGTCTATCTCACCAGAATTATTTTTTCAAAAAGGACAATTTAACAATGTCGATAACGTTATCATAAGCAAACCGATGAAAGGGACAATGCCTAGAGGTAAAACGGAAGCTGAAGATCAACAGTATTATAAATCATTGCAAACTTCTTCGAAAGATCGTGCAGAAAATGTCATGATTGTTGATTTGCTAAGAAACGATATAGGGAGAATATCACAGAGTGGCTCAATTAAGGTGTATAAACTATTTTTTATTGAGGCATATAAAACTGTATTTCAAATGACTTCGATGGTAAGTGGAACTTTAAAAACTAATACAGACTTAACTCAAATTTTAACATCGTTATTTCCTTGTGGTTCGATTACAGGTGCACCGAAACTGAATACAATGAAATATATTAAACAATTTGAAAGTTCACCTCGTGGTATATACTGCGGAGCAATTGGACTATTACTTCCAACTGAAGATGATAAAATGATTTTTAATATTCCGATTCGTACTATTGAGTATAAATATGGACAAGCGATTTATGGAGTCGGAGCAGGTATTACAATTGATTCTAAGCCAAAAGATGAAGTAAATGAATTTTACGCAAAAACCAAGATTTTGGAGATGTTATAA

Protein sequences of DBSCAN-SWA_1

>NC_002745|755279:763100|758531_759116_-|WP_000604990.1|DBSCAN-SWA
MILYILINIAIVVLITGFNLYRHQMQHLSLSAMLLSITINAFINTFIIDKYNFITLCTITMFIIWTILQFYIDKKLKPVYITDQKFIAIILTIVVSLTQRVTDFSSTQSIYMSIPFLAPAIFIIGGIMLFISTFNSLDETAENNNKIKKLMIKGLIIINISFIVMMVLTPYWYLYLIVYLIFLLFLLWQKVYKF
>NC_002745|755279:763100|755279_756335_-|WP_000244415.1|DBSCAN-SWA
MVLSIRSQIIIGVVSSILLTSTILAIAYILMWFNGHMTLTLTLTTIITSCLTLLICSIFINPLIQKIKQFNIKTKQFANGNYASNDKTFNSPKEIYELNQSFNKMASEITQQMNQIKSEQQEKTELIQNLAHDLKTPLASIISYSEGLRDGIITKDHEIKESYDILIKQANRLSTLFDDMTHIITLNTGKTYPPELIQLDQLLVSILQPYEQRIKHENRTLEVNFCSEIDAFYQYRTPLERILTNLLDNALKFSNVGSRIDINISENKDQDTIDIAISDEGIGIIPELQERIFERTFRVENSRNTKTGGSGLGLYIANELAQQNNAKISVSSDIDVGTTMTVTLHKLDITS
>NC_002745|755279:763100|756334_757021_-|WP_000149344.1|DBSCAN-SWA
MTHLLIVDDEQDIVDICQTYFEYEGYKVTTTTSGKEAISLLSNDIDIMVLDIMMPEVNGYDIVKEMKRQKLDIPFIYLTAKTQEHDTIYALTLGADDYVKKPFSPRELVLRINNLLTRMKKYHHQPVEQLSFDELTLINLSKVVTVNGHEVPMRIKEFELLWYLASRENEVISKSELLEKVWGYDYYEDANTVNVHIHRIREKLEKESFTTYTITTVWGLGYKFERSR
>NC_002745|755279:763100|756995_757469_-|WP_001037807.1|DBSCAN-SWA
MNKLLLLVTFIIRVGSGIVMLMQGYEKLTGGFTLKGLVPVIANNTDSPEWYKWFFANIVAHTTSLFDIVVPLGEIAIGLGLIFGVFAYAASFFGAFVMINYILADMIFTYPLQLTFFILLLMSHSLLKQISLKEIINYFRGRKNRGEKIDDPLTDRG
>NC_002745|755279:763100|761371_761965_+|WP_000604514.1|DBSCAN-SWA
MILVIDNNDSFTYNLIDYIKTQTKLTVQVVGIDNLLIEDVINMKPKAIVISPGPGNPDDYPILNEVLEQFYQRVPILGVCLGFQCIVSYFGGNIIHGYHPVHGHTTQLRHTNEGIFQGLPQNFNVMRYHSLIADGATFPNCLKITAKNDEAIIMAFEHIRFPVFGVQYHPESILSEYGYRQVELFLSKVGDYCENRI
>NC_002745|755279:763100|759931_760351_-|WP_000941336.1|DBSCAN-SWA
MLQQIYPSTTHPYQFELNKDFNFSAAHHIPCEEAGICQNVHGHTYFVNLTIVGDKLDDTGFLVNFSHLKKMIHGKFDHQLLNNLPAFKNKIPSTEIVAETIYQIVKENLASLEHQPKCIQVFVRETPTSYVVFRPKEQV
>NC_002745|755279:763100|760352_761021_-|WP_000446724.1|DBSCAN-SWA
MESVLNNEKAIVVFSGGQDSTTCLFYAKKHFKEVELVTFNYGQRHDTEIEVAKQIAQDQGMKHHVLDMSLLSQLTPNALTQHDMEITNNEDGIPNTFVPARNLLFLSFAGALAYQIGAKHIITGVCETDFSGYPDCRDSFIKSMNVTLSLAMDKDFVIHTPLMWLNKAETWKLSDELEVLDYIRTKTLTCYNGIIGDGCGECPACHLRQRGLNQYLESKGAL
>NC_002745|755279:763100|761948_763100_+|WP_001217791.1|DBSCAN-SWA
MRIEYNYRYYLTENEYKQYHIQLKGFIKKYVATKLADVGEVIHFAQAQQRQGRYVSLYLSYEAAKYFNHVMCTHSLAKDDIYAVAYSFEKAESINSTYEHQTSYVSKHHFSFVESSEVMMTNIKRVQQAIVEGETYQVNYTARLTDNIYYPISTLYERLTQFSNGNYTALLQTDEIQVASISPELFFQKGQFNNVDNVIISKPMKGTMPRGKTEAEDQQYYKSLQTSSKDRAENVMIVDLLRNDIGRISQSGSIKVYKLFFIEAYKTVFQMTSMVSGTLKTNTDLTQILTSLFPCGSITGAPKLNTMKYIKQFESSPRGIYCGAIGLLLPTEDDKMIFNIPIRTIEYKYGQAIYGVGAGITIDSKPKDEVNEFYAKTKILEML
>NC_002745|755279:763100|757811_758252_-|WP_001093562.1|DBSCAN-SWA
MNTKYFLAVGAVASVLTLGACGNSNSQDQGNKTEQKTKSEDSNVKTDKTKHLTGTFSSKNGETVEGKAEIKNGKLMLTNYKSSKGPDLYVYLTKNGDIKNGKEIAMVDYDKEKQTFDLKNVDLSKYDEVTIYCKKAHVIFGGAKLK
>NC_002745|755279:763100|759214_759928_-|WP_001062972.1|DBSCAN-SWA
MAKIPVLEIFGPTIQGEGRVIGRKTMFVRTAGCDYRCSWCDSAFTWDGSAKGDIKLMTAEEIYDELKRIGGDLFNHVTISGGNPALIKGIQELVDLFQDKGIFSALETQGSKFQPWMTQIDDLTISPKPPSSTMTPDLKKLDEVITQCVPSSLNLKVVVFDDKDYDFAKMIHHRYPDIPFYLQVGNPYLSDSVDNHTEKLLERYEQLVDLVMQSNDMNHVYVLPQLHTLLWSNKKGV

Homologous phage analysis in the prophage region

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000244415.1|755279_756335_-	two-component system sensor histidine kinase SaeS	A0A1V0SGX0	Hokovirus	3.6e-14	29.8
WP_000149344.1|756334_757021_-	response regulator transcription factor	NA	NA	NA	NA
WP_001037807.1|756995_757469_-	DoxX family protein	NA	NA	NA	NA
WP_001093562.1|757811_758252_-	DM13 domain-containing protein	NA	NA	NA	NA
WP_000604990.1|758531_759116_-	hypothetical protein	NA	NA	NA	NA
WP_001062972.1|759214_759928_-	7-carboxy-7-deazaguanine synthase QueE	A0A1U9WRB6	Streptococcus_virus	6.5e-52	43.5
WP_000941336.1|759931_760351_-	6-carboxytetrahydropterin synthase QueD	S4U060	uncultured_phage	6.3e-07	28.7
WP_000446724.1|760352_761021_-	7-cyano-7-deazaguanine synthase QueC	A0A2H4J8Q7	uncultured_Caudovirales_phage	9.6e-66	57.5
WP_000604514.1|761371_761965_+	aminodeoxychorismate/anthranilate synthase component II	A0A0P0IKJ1	Acinetobacter_phage	4.4e-38	42.9
WP_001217791.1|761948_763100_+	anthranilate synthase component I family protein	S4VNU7	Pandoravirus	4.6e-23	35.7

Sequences of DBSCAN-SWA_2

Nucleotide sequences of DBSCAN-SWA_2

>NC_002745|775071:789712|DBSCAN-SWA
TATGAAAGAACAACTTAATCAACTATCAGCATATCAGCCTGGTTTATCTCCAAGGGCATTGAAAGAAAAGTATGGCATTGAAGGAGATTTATATAAACTTGCATCAAATGAAAATTTGTATGGACCATCGCCTAAAGTTAAAGAAGCGATATCAGCACATTTAGATGAGTTATATTATTATCCTGAAACAGGATCACCGACATTAAAAGCGGCGATTAGTAAACATTTAAATGTAGATCAATCACGCATTTTATTTGGTGCGGGATTAGATGAAGTTATATTAATGATTTCTAGAGCAGTATTAACGCCAGGGGATACTATTGTTACAAGTGAAGCGACATTCGGTCAATATTATCACAATGCGATTGTTGAATCAGCTAATGTGATACAAGTACCTTTAAAAGATGGTGGCTTCGATTTAGAAGGTATTTTAAAAGAAGTTAATGAAGATACGTCATTGGTATGGTTATGTAATCCAAATAATCCTACAGGTACATATTTTAATCATGAGAGCTTAGATTCGTTTTTATCTCAAGTACCTCCACATGTACCAGTAATTATAGATGAAGCTTATTTTGAATTTGTGACAGCAGAGGACTACCCGGATACACTTGCTTTGCAACAAAAATATGACAATGCTTTCTTATTACGTACATTTTCAAAGGCGTATGGATTAGCGGGTTTACGTGTAGGATATGTGGTAGCAAGTGAACATGCGATTGAAAAATGGAACATCATTAGACCACCATTTAATGTGACACGTATATCTGAATACGCAGCAGTTGCAGCACTTGAAGATCAACAATATTTAAAAGAGGTAACACATAAAAATAGTGTTGAACGCGAAAGATTTTATCAATTACCTCAAAGTGAGTATTTCTTGCCAAGTCAAACGAATTTTATATTTGTAAAAACAAAGCGGGTAAATGAACTTTATGAAGCACTTTTAAATGTAGGGTGTATTACGCGACCATTTCCAACTGGTGTTAGAATTACAATTGGTTTTAAAGAACAAAATGATAAAATGTTAGAAGTTTTATCAAATTTTAAATACGAATAGTAAGTGGGGAGTGGGACAGAAATGATATTTTCTCAAAATTTATTTCGTCGTCCCACCCCAACTTGCATTGCCTGTAGAATTTCTTTTCGAAATTCTCTGTGTTGGGGCCCCTGACTAGAATTGAAAAAAGCTTGTTACAAGCGCATTTTCGTTCAGTCAACTACTGCCAATATAACTTTGTAGAGCATTGAACATTGATTTATGTCTCAAGCTCAATGCAGTGTGAATGATGAGGTGAGAGTATTCAGTGTAAAAAGCAACAATAGATGATATTGTTTTGTATCAATTGCTTTTTTGCTATACTGAATCAATACTGATATTTTGAGGAGAAGATTAAAATGACCCGTAAATCAATCGCGATTGATATGGATGAAGTATTGGCAGATACATTAGGAGAAATCATTGATGCTGTCAATTTTAGAGCGGATTTAGGTATTAAAATGGAAGCTTTGAATGGTCAAAAACTTAAACATGTTATTCCTGAACATGATGGATTAATTACAGAAGTATTGAGAGAACCAGGCTTCTTCAGACATCTTAAAGTGATGCCACATGCACAAGAAGTTGTGAAAAAATTAACTGAACATTATGATGTATATATTGCTACAGCAGCAATGGATGTACCAACATCATTTAGTGATAAATATGAATGGTTACTAGAGTTCTTTCCATTTTTAGATCCTCAGCATTTTGTTTTTTGTGGTAGAAAAAACATCGTTAAAGCTGATTATTTAATAGATGACAATCCTAGACAGCTTGAAATTTTTACTGGTACACCGATTATGTTTACAGCAGTGCATAATATTAATGATGATCGATTTGAACGCGTAAATAGCTGGAAAGATGTAGAACAGTATTTTTTAGATAATATTGAGAAATAAAATATATCACTTGAAAAATTTCATGTAGAAAAGATGATGGATAGGCTATAAAGTAATTGTGACTGAGATGAACTTTTATGTCTTAGACACTACAACACTATATTGGCAGTAGTTGACTGCGGGGCCCCAACATAGAGAAATTGGATTCCCAATTTCTACAGACAATGCAAGTTGGCGGGGCCCCAACATAGAGAAATTGGAACGCCAATTTCTACAGACAATGCAAGTTGGGGTGGGCCCCAACATAAAGAAATACTTTTTCTTTAGAAATTAGTATTTCTTATGGGAGTGGGACATAAATCAATGTTCTATGCTCTACGAAGTTATATTGGCAGTAGTTGACTGAACGAAAATGCGCTTGTAACAAGCTTTTTTCAATTCTAGTCAACCTTGCCGGCGGGGCCCCAACACAGAGAAATTGGATTCCCAATTTCTACAGACAATGCAAGTTGGGGTGGGACGACGAAATAAATTTTGCGAAAATATCATTTCTGTCCCACTCCCTCCTATTTTTAAGTACACATTAGCTTTGACTAATGATAAAGAATCGCTACATAATCAATCATTAGTCGTTCTTTATCATTTCCGTCCCGCTCTCAATAAATGTTAGTCTATCTCATTATTATAAATCGGATGAATGTGTTAATCTATGGCAGATTACACGTCATCCGATTTTTTATAGAATTTGAAAAAGACGCATAAACCACTATGATTTAAAATACAACATCAATCATTTTAGTGGCATGCGCCAAAATTATATGTCTGTTTTTGAAACAGGGTAATAGCTTAAAGCTAATAAAAACGAATATAAGGTGCGTTGAATCTTATGATTACACTCCAAACCTAATATAATATCGGGTCAAGATCATTCCGGATGCTTACAAATCATTGACAGTAAGTAACTGAATAGCATTTGGTATAACCTCAATATCAATAGGTGTTTCTAATGAAATTTCGCCATCAATATCAACTTTCATTGCTGGATCTGTTGTAAGTGAAATCTTTTTACCAGGTATATGCTCAATACCTTGAGTAATTTCATTCCAATTCATGCTATCACGCTTTTTAAAAATATCATTTAAAATACTGAAACTTTGTTCATTAAAAATGAAAGTGTTCAGTTCACCATCTTGAGGAGACAAATCAGTCAATGGTATACGACTACCACCAATGAATGGACCATTTGCTGTTAGTATCATGGTCGTTTCGCCAGAATATGTCTTATCATCTATTGATAATTGATAATTAAATTGTGTTGGATTTAGCAGTGTTTTGACAGTTGATCCAATATAACTCAATTTACCAAATATATCTTTTGAACCATCTTGTACGTTTTCAGCGTTTTGAACAATGAGACCTAAGCCAACAAAGTTGAGTGCATATTGATTATTTATTTTAATTACATCGTATGTACCAACTTGTGCAGAAATCATTTGTTCACTAGCTTGTTTATGATTAGGTGCTATATTTAGCGTTTTTGTAAAATCATTAAAAGTACCGCCTGGTAAAATGCCAATAGGGAGTTGAAGGTCATGTGACATAACACCATTTATAAGTTCGTTAACCGTGCCATCACCGCCAAGAATAAATAATATATCTACATCTTTTGCATAGTTTTTAGTTTTGATTTCTTGGCAATATTTAATAATGTCACCTTCGTTTTCACTCAATTGAATAGAAAGATGCTTACAAATTGAACTTAATGCTGTTGTAACTTCCCCAATACCTTGATTAATATTTTTTAATCCACTGTGTTCATGGTAAAAGAGGACACCATGTGTATATTTATTTTCCATAGTTTAGCCTACTTTCTAAAAATTGGTTCATTAAATATATATACCCACTTTTAATTGTTAATACCAAAAATATGTTTTTAAATAGAGAAAATGGTAATAACTGACATTGATGTCTATAGAGTGGGACGAGAAAATATAGTTATAGCTGTCTATAACGAGCATATTAAGCTTTTATTTATACTGATATCTTGAATTTAATTAATAGAAACCTATAAAAAAACAGTAAGCCATTTAAATGACTTACTGTTTTTTGAATTAGGCCAACAATATTAACGTATACCTTTCATCGCTTTGATGATTAAAGGTGAGAATGCTAATACAATTGTTGTAACAATAATTGCAACAACACCTAGGAAAATAAAGTAATTTGTTTGACCTAGTGGTTCTATTAACTTAACTAAAGTACCATTGATTGCTTGTGCAGAAGCGTTAGTTAAGTACCAAATACTCATCATTTGGGCATTAAATGCTTTAGGTGCTAACTTAACAGCAGCACTATTACCCGTTGGTGATAAGCATAGCTCACCGATAACACAAATAATGTACGATAAAATAACCCAGTTAACTGAGAAGTTTGATGAACCTGATGCATAACCTACAATACCAATTAGTATGTATGACGCACCTGCTAAGAACGTACCAATTGCAAATTTTACTGGCAGGCTAGGTTGTTTAGTTCCAAGCTTTTGCCATAAAAGTGAAATAATTGGAGCTAATAATAAAATAAATAATGGGTTAATTGATTGGAAGATCGCTTCACCAAAGTTTGTTTTCCAACCAAATAAGTTTAATTTCATATCTGAATGTTCAATTCCATATATGTTTAATACATTAGACCCTTGTTCTTGAATAGCCCAGAACACCATTCCAAGAATAAATAATGGAATAAATGCTTTAACACGAGAACGTTCAGTATCAGTGACATCTTTACTTCTAATAATTAAAGTGAAGTAAATGATTGGTAATGCAATACCTAATACTAAAACAGTATTACTAACTAAGTTAAATGATAATGAGTTAGTTAATGCACCAATAACGATAATTAATACAATTGCTAAGACAACACTTCCGATAATAAGACCATACTTTTTCTTTTCAGCTGGTGTCAATGGGTTAGTAGGTTTCATACCAACGCTACCTAAGTTTTTGCGGTTGAAAAGTACATACCATACTAAACCTAATGCCATACCAACTGCTGCAATCAAGAATCCGCCGTGGAAGTTTTTAACATTAACAAAGTGTTGCAAAATAATAGGTGATAATAATGCACCCATATTAACTGACATATAGAAAATAACAAAACCTGCATCCATACGTCTATCATTTTCAGGATATAAACGGCCAACGATATTTGAAATGTTTGGCTTCATTAAACCTGAACCAATAATGATGAAGAACATTGATGTGAATAAGCCGATTAATGCAAATGGTAAGCTTAAACAAATATGTCCGATAATAATAAAGACTGCACCTAATAAAGTAGCGCCTCTAGTGCCTGTAATTCTGTCAGCAATCCATCCGCCTGGTATTGATGTCATATAGATTAATGAACCATAAACTGACATAATTGACATAGCTGTTGTTTTATCAATTCCAAGGCCATTATCTGTTACGGCAAAGTACATGTAGAAAATGAGTAGGGCACGCATGCCATAATAACTAAACCTTTCCCAGAACTCTACAAAGAAGAGTACGCCTAGTCCTCGAGGATGCCCGAAAAATCCTGTTTGAGGTATGTCTTGAATTTGATTTCCATGGGAGTTTTGTTGTGTCATGTATACATCCCATCCTTTCTTCCCCTAATACAATAGTTTAAGTAAATTTGATTGTGCCTTATCAACTAAATATTCCAACAAATCACAAAAAAATAAAAATATTGAGAATATTCTGTTATTAAGCGCGCACAATTAATTAGAGATAATATAAAAATATACTTATTGACGTTAAAGTGCAATAGGTTTCTATAAAAATGTTGTTTAATTCGTGTACTAATATTCTTTTGGTGTACTTTGGTATAAAATGTTATTTTAATGTAACCTATTATGTATGCTAAATGAAAAACACACCAATAAGTTAGGAAAATCAACTTATTGGTGTGTTTATTAAATGATACATTTAACGATTATCTATTTTTTCGGGATATAAATCATGATTCATCAAACGATGCTCAGCCATTTTTTCATATTTAGAATTTGGACGTCCATAGTTTGTATAAGGATCAATAGAAATTCCACCACGTGGTGTGAACTTGCCCCAGACTTCAATATAATGTGGGTCCATAAGCTCTATCAAATCATTCATAATAATATTCATACAATCTTCGTGAAAATCACCGTGATTTCTGAAACTAAATAAGTATAATTTCAAAGATTTTGATTCAACCATTTTAACATTTGGAATATATGAAATATAGATAGTTGCAAAATCTGGTTGCCCAGTAATTGGACATAATGATGTAAATTCTGGACAGTTGAATTTTACGAAATAGTCACGACCTTGATGCTTATTATCAAACGATTCTAATACATCAGGACGATAGTCAAAATTGTAAGTATTGTCTTGATTTCCTAATAAAGTTATATCTTGTAATTCATCTTGTTGACGGCCATGTGCCATATAAAGCGCTCCTTTAAATTTATTTTTTTATTATTTTGGCGTCTCGGCGTGCTTTTTCAAACATGTAATAACTTGCACCGATAATAACGACGTAACCTAATGTTGCATAGAAATCTGGAGATTCTCCGAATAGAACAAATCCAAGTATTGCTGTGAAAATTATAGATGCATACGTAAAAATAGAAATATCTTTTGCTGCTGCAAAACTATATGCTAAAGTAACACCAATTTGACCCACAGCGGCAGCTAAGCCAGCCCCTAATAGATAAAGTATTTGCATCTGACTCATTGGTTCATAAGTATATGCAGTGAAAGGTATTAAAACGATGACAGAAAATAAGGAGAAGTAAAATACTATAGTATATGGTGCTTCTCTTGAACTAAGTGCTCGAACACATGTATATGCTGATGCTGCAAAAATACCTGAGAATAAGCCAGCTAATGATGGAATCATAGATGATGAAAATTCAGGTTTCACTATTAAAAGCATACCTAAAATAGCAATTATCATTGCTGTAATTTGATACTTCCTTACCTTTTCATGTAAGAAAACAATGCTTAATAAAATCGTCCAGAAAGGATTGAGTTTCATTAATGAATCGGCATCACTAAGTACCATATGATCAATGGCATAAATATTTAACAATACACCAATAAGTCCAAGTGTTGATCGTGTTATTAATAAGGGTTGACTTGAAAGTCTGCCAAACATTGGCTGATGGTATTTATATAAAAAAAATAATGGAATAAACATTGCTACTAAGTTTCGTGCTAATGATTTTTGAAAAACAGGAAGGTCACCTGCAAGTCTGAAAAACACTGACATAAAACTGAAACCAATAGCCGAAATTAAAATGGCAATGATACCTTTTACTTTAGGATTCAATTTTATCGCCTCTTTTATATAAAATTAACGTATTTATATTAGCATAAAACAACATGTTGTGCATAAATAGTTGAAATTTACTATAAAAAGACTATAATAGACTGTACCGAACAAACGTTCTGTGTTTATTTGTCGGAATAATAGGGCATTACACTTTTATGAATGTTTGTGTTATTACATAAAACAAATATCAATTCAGTATCAAGCTAATAAGCTTTTTCTTGATTTCTGTTGATACAATTGAGATTGACACAGATTTAAAAAAATCAAGTGATATCTACTAAAAAATTTTTTTAAATTTGTTCAAGTTTTTCTAATTTAGTATTGGTGCCTAGTTGGAACGTTTTACGAACATTCGATTAGAAAATGGCACTTTAAATCATAGTGTGTCTTATGTATAATGAAACACATAATATAGTGTTGGTGAAACGAAAAAGACACAATATCTTGTGTTTTGTATGCAAATGCTTTATTTATGAAGAAATTACATTTAAAAGTAATTTAACACAGAAATTTAATAGTTATTATCAATTAATAGTCATATTTTTAGAAAATGTACTGAGCAAATGGAAGATATCCAATGATGTAAATACTACATATAGTGATTTTTATACATTCAACCCATATAAGCTACTATTTTCTCAAATATAAATCTATGCAATTGGTTTACATTTGAGAAAATAAGTAGCTTCATTATAGTTAATACAATGCTGAGATAACCATAGTAACCATGTTGTTAAAGCATTTTTTAATTGGAATGACTACTTTATTTAAAAGGGTTGAAGAAAGAAGGTGATCCAATGAAAATAATATATTTTTCATTTACTGGAAATGTCCGTCGTTTTATTAAGAGAACAGAACTTGAAAATACGCTTGAGATTACAGCAGAAAATTGTATGGAACCAGTTCATGAACCGTTTATTATCGTTACTGGCACTATTGGATTTGGAGAAGTACCAGAACCCGTTCAATCTTTTTTAGAAGTTAATCATCAATACATCAGAGGTGTGGCAGCTAGCGGTAATCGAAATTGGGGACTAAATTTCGCAAAAGCGGGTCGCACGATATCAGAAGAGTATAATGTCCCTTTATTAATGAAGTTTGAGTTACATGGAAAAAACAAAGACGTTATTGAATTTAAGAACAAGGTGGGTAATTTTAATGAAAACCATGGAAGAGAAAAAGTACAATCATATTGAATTAAATAATGAGGTCACTAAACGAAGAGAAGATGGATTCTTTAGTTTAGAAAAAGACCAAGAAGCTTTAGTAGCTTATTTAGAAGAAGTAAAAGACAAAACAATCTTCTTCGATACTGAAATCGAGCGTTTACGTTATTTAGTAGACAACGATTTTTATTTCAATGTGTTTGATATTTATAGTGAAGCGGATCTAATTGAAATCACTGATTATGCAAAATCAATCTCGTTTAATTTTGCAAGTTATATGTCAGCTAGTAAATTTTTCAAAGATTACGCTTTGAAAACAAATGATAAAAGTCAATACTTAGAAGACTATAATCAACACGTTGCCATTGTTGCTTTATACCTAGCAAATGGTAATAAAGCACAAGCTAAACAATTTATTTCTGCTATGGTTGAACAAAGATATCAACCAGCGACACCAACATTTTTAAACGCAGGCCGTGCGCGTCGTGGTGAGCTAGTGTCATGTTTCTTATTAGAAGTGGATGACAGCTTAAATTCAATTAACTTTATTGATTCAACTGCAAAACAATTAAGTAAAATTGGGGGCGGCGTTGCAATTAACTTATCTAAATTGCGTGCACGTGGTGAAGCAATTAAAGGAATTAAAGGCGTAGCGAAAGGCGTTTTACCTATTGCTAAGTCACTTGAAGGTGGCTTTAGCTATGCAGATCAACTTGGTCAACGCCCTGGTGCTGGTGCTGTGTACTTAAATATCTTCCATTATGATGTAGAAGAATTTTTAGATACTAAAAAAGTAAATGCGGATGAAGATTTACGTTTATCTACAATATCAACTGGTTTAATTGTTCCATCTAAATTCTTCGATTTAGCTAAAGAAGGTAAGGACTTTTATATGTTTGCACCTCATACAGTTAAAGAAGAATATGGTGTGACATTAGACGATATCGATTTAGAAAAATATTATGATGACATGGTTGCAAACCCAAATGTTGAGAAAAAGAAAAAGAATGCGCGTGAAATGTTGAATTTAATTGCGCAAACACAATTACAATCAGGTTATCCATATTTAATGTTTAAAGATAATGCTAACAGAGTGCATCCGAATTCAAACATTGGACAAATTAAAATGAGTAACTTATGTACGGAAATTTTCCAACTACAAGAAACTTCAATTATTAATGACTATGGTATTGAAGACGAAATTAAACGTGATATTTCTTGTAACTTGGGCTCATTAAATATTGTTAATGTAATGGAAAGCGGAAAATTCAGAGATTCAGTTCACTCTGGTATGGACGCATTAACTGTTGTGAGTGATGTAGCAAATATTCAAAATGCACCAGGAGTTAGAAAAGCTAACAGTGAATTACATTCAGTTGGTCTTGGTGTGATGAATTTACACGGTTACCTAGCAAAAAATAAAATTGGTTATGAGTCAGAAGAAGCAAAAGATTTTGCAAATATCTTCTTTATGATGATGAATTTCTACTCAATCGAACGTTCAATGGAAATCGCTAAAGAGCGTGGTATCAAATATCAAGACTTTGAAAAGTCTGATTATGCTAATGGCAAATATTTCGAGTTCTATACAACTCAAGAATTTGAACCTCAATTCGAAAAAGTACGTGAATTATTCGATGGTATGGCTATTCCTACTTCTGAGGATTGGAAGAAACTACAACAAGATGTTGAACAATATGGTTTATATCATGCATATAGATTAGCAATTGCTCCAACACAAAGTATTTCTTATGTTCAAAATGCAACAAGTTCTGTAATGCCAATCGTTGACCAAATTGAACGTCGTACTTATGGTAATGCGGAAACATTTTACCCTATGCCATTCTTATCACCACAAACAATGTGGTACTACAAATCAGCATTCAATACTGATCAGATGAAATTAATCGATTTAATTGCGACAATTCAAACGCATATTGACCAAGGTATCTCAACGATCCTTTATGTTAATTCTGAAATTTCTACACGTGAGTTAGCAAGATTATATGTATATGCGCACTATAAAGGATTAAAATCACTTTACTATACTAGAAATAAATTATTAAGTGTAGAAGAATGTACAAGTTGTTCTATCTAACAATTAAATGTTGAAAATGACAAACAGCTAATCATCTGGTCTGAATTAGCAGATGATTAGACTGCTATGTCTGTATTTGTCAATTATTGAGTAACATTACAGGAGGAAATTATATTCATGATAGCTGTTAATTGGAACACACAAGAAGATATGACGAATATGTTTTGGAGACAAAATATATCTCAAATGTGGGTTGAAACAGAATTTAAAGTATCAAAAGACATTGCAAGTTGGAAGACTTTATCTGAAGCTGAACAAGACACATTTAAAAAAGCATTAGCTGGTTTAACAGGCTTAGATACACATCAAGCAGATGATGGCATGCCTTTAGTTATGCTACATACGACTGACTTAAGGAAAAAAGCAGTTTATTCATTTATGGCGATGATGGAGCAAATACACGCGAAAAGCTATTCACATATTTTCACAACACTATTACCATCTAGTGAAACAAACTACCTATTAGATGAATGGGTTTTAGAGGAACCCCATTTAAAATATAAATCTGATAAAATTGTTGCTAATTATCACAAACTTTGGGGTAAAGAAGCTTCGATATACGACCAATATATGGCCAGAGTTACGAGTGTATTTTTAGAAACATTCTTATTCTTCTCAGGTTTCTATTATCCACTATATCTTGCTGGTCAAGGGAAAATGACGACATCAGGTGAAATCATTCGTAAAATTCTTTTAGATGAATCTATTCATGGTGTATTTACCGGTTTAGATGCACAGCATTTACGAAATGAACTATCTGAAAGTGAGAAACAAAAAGCAGATCAAGAAATGTATAAATTGCTAAATGACTTGTATTTAAATGAAGAGTCATACACAAAAATGTTATACGATGATCTTGGAATCACTGAAGATGTGCTAAACTATGTTAAATATAATGGAAACAAAGCACTTTCAAACTTAGGCTTTGAACCTTATTTTGAGGAACGTGAATTTAACCCAATCATTGAGAATGCCTTAGATACAACAACTAAAAACCATGACTTCTTCTCAGTAAAAGGTGATGGTTATGTATTAGCATTAAACGTAGAAGCATTACAAGATGATGACTTTGTATTTGACAACAAATAACAATTAAATTAAAAGACCTTCACATGTAAAGGGAAATAGCGATTCGTTTCGTCTTGTCTCCTACATGTTGAAGGTCTTTTCTCTATGCTTAAAAGCGTATGCATATTTTGAAAAAGTAAAAATTGTATTTAATGATGTCAATGAGGCTAGAAAGTATACAAGATATTGCATTACAAAAGGGTGTTCTATTTTACTTTAAGCAAACAAAATACACATTCCGAAAAATTAAATTTCAGTTTAATTGCAAATATCAATAAAATTGACACTAAATTATTTGAAAGGCTATTGAAATTATGGTCAAAAAACGCTACTATTAATGAGAAATATTATCAATGATAATGATTATCATTAATTTAAAGGGAGAAAAATTTGTAATGAAGTATTTATTAAAGGGAAATATTTTGCTTCTATTACTAATATTGTTGACAATTATTTCGTTGTTCATAGGTGTGAGTGAACTATCAATTAAAGATTTACTACATTTAACTGAATCACAGCGGAATATTTTATTCTCAAGCCGAATACCAAGGACGATGAGTATTTTAATTGCTGGAAGTTCGTTGGCTTTAGCAGGCTTGATAATGCAACAAATGATGCAAAATAAGTTTGTTAGTCCGACTACAGCTGGAACGATGGAATGGGCTAAACTAGGTATTTTAATTGCTTTATTGTTCTTTCCAACCGGTCATATTTTATTAAAACTAGTATTTGCTGTTATTTGCAGTATTTGCGGTACGTTTTTATTTGTTAAAATCATTGATTTTATAAAAGTGAAAGATGTCATTTTTGTACCGCTTTTAGGAATTATGATGGGTGGGATTGTTGCAAGTTTCACAACCTTCATCTCATTGCGCACGAATGCTGTTCAAAGCATTGGTAACTGGCTTAACGGGAACTTTGCCATTATCACAAGTGGACGCTATGAAATTTTATATTTAAGTATTCCTCTTTTAGCATTGACATATCTTTTTGCTAATCATTTCACGATTGTAGGAATGGGTAAAGACTTTACTAATAATTTAGGTTTGAGTTACGAAAAATTAATTAACATCGCATTGTTTATTACTGCAACTATTACAGCATTGGTAGTGGTGACTGTTGGAACATTACCGTTCTTAGGACTAGTAATACCAAATATTATTTCAATTTATCGAGGTGATCATTTGAAAAATGCTATCCCTCATACGATGATGTTAGGTGCCATCTTTGTATTATTTTCTGATATAGTTGGCAGAATTGTTGTTTATCCATATGAAATAAATATTGGTTTAACAATAGGTGTATTTGGAACAATCATTTTCCTTATCTTGCTTATGAAAGGTAGGAAAAATTATGCGCAACAATAATAAAAAAATAATGCTTTTAATTGCAGTAACGTTATTAATTAGTATGCTGTACTTATTTGTAGGTATTGATTTTGAAATATTTGAATATCAATTTTCAAGTCGTTTAAGAAAGTTCATATTAATTATTTTAGTAGGTGCTGCCATTGCAACTTCAGTGGTGATTTTTCAAGCGATTACAAATAACCGTCTATTGACACCATCAATAATGGGGTTAGATGCAGTTTATTTATTTATCAAAGTATTGCCAGTCTTTTTATTTGGAATTCAATCGGTATGGGTTACTAATGTATATTTGAACTTTATATTAACACTTATAACGATGGTGTTATTCGCACTAATCCTATTCCAAGGTATCTTTAAAATTGGACATTTTTCAATTTATTTTATCTTACTTATTGGTGTCCTTTTAGGAACATTTTTTAGAAGCATAACAGGTTTTATTCAACTGATTATGGATCCTGAGTCATTTTTAGCAATACAAAGTAGTATGTTTGCTAATTTTAATGCTTCTAATTCGAATTTAGTTACTTTCTCAGCAGTGCTATTAGTAATCTTATTAGTCATTACAATTTTACTATTGCCTTATTTAGATGTATTGCTTTTAGGTCGTGCTGAAGCAATTAATCTTGGGATATCGTATGAAAAATTAACGCGAATTCTACTTGTAATAGTCTCAGTTTTAGTTTCTGTGTCAACTGCATTAGTAGGACCAATTACATTTTTAGGTTTATTAACTGTAAATCTAGCGCATGAACTAATGAAGACGTATGAACATAAGTATATTTTAATTGCGACAATTTGCTTGAGTTGGATTAGTTTATTTAGTGCGCAATGGGTAGTTGAAAATGTGTTTGAAGCTACGACAGAAATGAGTATACTTATTGATTTGATTGGTGGAAGTTATTTCATTTATCTATTAGTTAGAAGGAGAAATGCGCAATGATTCAAGTTGAAAATTTAACTAAAACTATAAATAATCAAATGATATTGGAAGATATTAGCATAGATATCGAAAAAGGTAAATTGACTTCTTTAATTGGACCTAATGGTGCGGGTAAGAGTACTTTACTTTCAGCGATATGTAGGTTAATTCGTTTTGATAACGGTGAAGTGAAAATAGATGGACAGCTCATGTCTGATTATAAAAATAATGACTTGTCGAAAAAAATATCTATATTAAAACAAACAAACCATACTGAAATGAATATTACGGTAGAGCAGTTGGTAAACTTTGGACGATTCCCTTATTCTAAAGGTCGTTTGACGAAAGAGGATCATGATATTGTCAATGATGCGCTAGATTTGTTGCAACTACAAGATATCAGAAATCGTAATATTAAGTCATTATCTGGTGGACAACGTCAGCGTGCATACATTGCAATGACAATAGCACAAGATACTGAATATATTTTGCTAGATGAACCATTAAATAATTTAGATATGAAGCATGCTGTTCAAATTATGCAAACGTTAAAAATGTTAGCGCATAAAATGAATAAAGCGATTGTCATTGTGTTACATGATATTAACTTTGCGTCCTGTTATTCAGATCAGATTGTAGCATTGAAAAACGGACAACTAGTTAAGTCAGATTTGAAAGATAATGTCATTCAAAGTAGTGTTTTAAGTGATTTATATGACATGAATATTCAAATTGAACATATAAGAAATCAAAGGATTTGTTTATATTTTAAGGATTGA

Protein sequences of DBSCAN-SWA_2

>NC_002745|775071:789712|777889_778807_-|WP_000429006.1|DBSCAN-SWA
MENKYTHGVLFYHEHSGLKNINQGIGEVTTALSSICKHLSIQLSENEGDIIKYCQEIKTKNYAKDVDILFILGGDGTVNELINGVMSHDLQLPIGILPGGTFNDFTKTLNIAPNHKQASEQMISAQVGTYDVIKINNQYALNFVGLGLIVQNAENVQDGSKDIFGKLSYIGSTVKTLLNPTQFNYQLSIDDKTYSGETTMILTANGPFIGGSRIPLTDLSPQDGELNTFIFNEQSFSILNDIFKKRDSMNWNEITQGIEHIPGKKISLTTDPAMKVDIDGEISLETPIDIEVIPNAIQLLTVNDL
>NC_002745|775071:789712|780922_781423_-|WP_000930014.1|DBSCAN-SWA
MAHGRQQDELQDITLLGNQDNTYNFDYRPDVLESFDNKHQGRDYFVKFNCPEFTSLCPITGQPDFATIYISYIPNVKMVESKSLKLYLFSFRNHGDFHEDCMNIIMNDLIELMDPHYIEVWGKFTPRGGISIDPYTNYGRPNSKYEKMAEHRLMNHDLYPEKIDNR
>NC_002745|775071:789712|787997_788954_+|WP_001245577.1|DBSCAN-SWA
MRNNNKKIMLLIAVTLLISMLYLFVGIDFEIFEYQFSSRLRKFILIILVGAAIATSVVIFQAITNNRLLTPSIMGLDAVYLFIKVLPVFLFGIQSVWVTNVYLNFILTLITMVLFALILFQGIFKIGHFSIYFILLIGVLLGTFFRSITGFIQLIMDPESFLAIQSSMFANFNASNSNLVTFSAVLLVILLVITILLLPYLDVLLLGRAEAINLGISYEKLTRILLVIVSVLVSVSTALVGPITFLGLLTVNLAHELMKTYEHKYILIATICLSWISLFSAQWVVENVFEATTEMSILIDLIGGSYFIYLLVRRRNAQ
>NC_002745|775071:789712|775071_776130_+|WP_000663030.1|DBSCAN-SWA
MKEQLNQLSAYQPGLSPRALKEKYGIEGDLYKLASNENLYGPSPKVKEAISAHLDELYYYPETGSPTLKAAISKHLNVDQSRILFGAGLDEVILMISRAVLTPGDTIVTSEATFGQYYHNAIVESANVIQVPLKDGGFDLEGILKEVNEDTSLVWLCNPNNPTGTYFNHESLDSFLSQVPPHVPVIIDEAYFEFVTAEDYPDTLALQQKYDNAFLLRTFSKAYGLAGLRVGYVVASEHAIEKWNIIRPPFNVTRISEYAAVAALEDQQYLKEVTHKNSVERERFYQLPQSEYFLPSQTNFIFVKTKRVNELYEALLNVGCITRPFPTGVRITIGFKEQNDKMLEVLSNFKYE
>NC_002745|775071:789712|779076_780582_-|WP_000193751.1|DBSCAN-SWA
MTQQNSHGNQIQDIPQTGFFGHPRGLGVLFFVEFWERFSYYGMRALLIFYMYFAVTDNGLGIDKTTAMSIMSVYGSLIYMTSIPGGWIADRITGTRGATLLGAVFIIIGHICLSLPFALIGLFTSMFFIIIGSGLMKPNISNIVGRLYPENDRRMDAGFVIFYMSVNMGALLSPIILQHFVNVKNFHGGFLIAAVGMALGLVWYVLFNRKNLGSVGMKPTNPLTPAEKKKYGLIIGSVVLAIVLIIVIGALTNSLSFNLVSNTVLVLGIALPIIYFTLIIRSKDVTDTERSRVKAFIPLFILGMVFWAIQEQGSNVLNIYGIEHSDMKLNLFGWKTNFGEAIFQSINPLFILLLAPIISLLWQKLGTKQPSLPVKFAIGTFLAGASYILIGIVGYASGSSNFSVNWVILSYIICVIGELCLSPTGNSAAVKLAPKAFNAQMMSIWYLTNASAQAINGTLVKLIEPLGQTNYFIFLGVVAIIVTTIVLAFSPLIIKAMKGIR
>NC_002745|775071:789712|783470_785576_+|WP_000855514.1|DBSCAN-SWA
MKTMEEKKYNHIELNNEVTKRREDGFFSLEKDQEALVAYLEEVKDKTIFFDTEIERLRYLVDNDFYFNVFDIYSEADLIEITDYAKSISFNFASYMSASKFFKDYALKTNDKSQYLEDYNQHVAIVALYLANGNKAQAKQFISAMVEQRYQPATPTFLNAGRARRGELVSCFLLEVDDSLNSINFIDSTAKQLSKIGGGVAINLSKLRARGEAIKGIKGVAKGVLPIAKSLEGGFSYADQLGQRPGAGAVYLNIFHYDVEEFLDTKKVNADEDLRLSTISTGLIVPSKFFDLAKEGKDFYMFAPHTVKEEYGVTLDDIDLEKYYDDMVANPNVEKKKKNAREMLNLIAQTQLQSGYPYLMFKDNANRVHPNSNIGQIKMSNLCTEIFQLQETSIINDYGIEDEIKRDISCNLGSLNIVNVMESGKFRDSVHSGMDALTVVSDVANIQNAPGVRKANSELHSVGLGVMNLHGYLAKNKIGYESEEAKDFANIFFMMMNFYSIERSMEIAKERGIKYQDFEKSDYANGKYFEFYTTQEFEPQFEKVRELFDGMAIPTSEDWKKLQQDVEQYGLYHAYRLAIAPTQSISYVQNATSSVMPIVDQIERRTYGNAETFYPMPFLSPQTMWYYKSAFNTDQMKLIDLIATIQTHIDQGISTILYVNSEISTRELARLYVYAHYKGLKSLYYTRNKLLSVEECTSCSI
>NC_002745|775071:789712|778897_778999_+|WP_031760357.1|DBSCAN-SWA
MVITDIDVYRVGRENIVIAVYNEHIKLLFILIS
>NC_002745|775071:789712|785693_786665_+|WP_000562498.1|DBSCAN-SWA
MIAVNWNTQEDMTNMFWRQNISQMWVETEFKVSKDIASWKTLSEAEQDTFKKALAGLTGLDTHQADDGMPLVMLHTTDLRKKAVYSFMAMMEQIHAKSYSHIFTTLLPSSETNYLLDEWVLEEPHLKYKSDKIVANYHKLWGKEASIYDQYMARVTSVFLETFLFFSGFYYPLYLAGQGKMTTSGEIIRKILLDESIHGVFTGLDAQHLRNELSESEKQKADQEMYKLLNDLYLNEESYTKMLYDDLGITEDVLNYVKYNGNKALSNLGFEPYFEEREFNPIIENALDTTTKNHDFFSVKGDGYVLALNVEALQDDDFVFDNK
>NC_002745|775071:789712|787039_788011_+|WP_000876318.1|DBSCAN-SWA
MKYLLKGNILLLLLILLTIISLFIGVSELSIKDLLHLTESQRNILFSSRIPRTMSILIAGSSLALAGLIMQQMMQNKFVSPTTAGTMEWAKLGILIALLFFPTGHILLKLVFAVICSICGTFLFVKIIDFIKVKDVIFVPLLGIMMGGIVASFTTFISLRTNAVQSIGNWLNGNFAIITSGRYEILYLSIPLLALTYLFANHFTIVGMGKDFTNNLGLSYEKLINIALFITATITALVVVTVGTLPFLGLVIPNIISIYRGDHLKNAIPHTMMLGAIFVLFSDIVGRIVVYPYEINIGLTIGVFGTIIFLILLMKGRKNYAQQ
>NC_002745|775071:789712|781442_782309_-|WP_001068501.1|DBSCAN-SWA
MNPKVKGIIAILISAIGFSFMSVFFRLAGDLPVFQKSLARNLVAMFIPLFFLYKYHQPMFGRLSSQPLLITRSTLGLIGVLLNIYAIDHMVLSDADSLMKLNPFWTILLSIVFLHEKVRKYQITAMIIAILGMLLIVKPEFSSSMIPSLAGLFSGIFAASAYTCVRALSSREAPYTIVFYFSLFSVIVLIPFTAYTYEPMSQMQILYLLGAGLAAAVGQIGVTLAYSFAAAKDISIFTYASIIFTAILGFVLFGESPDFYATLGYVVIIGASYYMFEKARRDAKIIKK
>NC_002745|775071:789712|776468_777011_+|WP_000197262.1|DBSCAN-SWA
MTRKSIAIDMDEVLADTLGEIIDAVNFRADLGIKMEALNGQKLKHVIPEHDGLITEVLREPGFFRHLKVMPHAQEVVKKLTEHYDVYIATAAMDVPTSFSDKYEWLLEFFPFLDPQHFVFCGRKNIVKADYLIDDNPRQLEIFTGTPIMFTAVHNINDDRFERVNSWKDVEQYFLDNIEK
>NC_002745|775071:789712|786845_787001_+|WP_000499195.1|DBSCAN-SWA
MFYFTLSKQNTHSEKLNFSLIANINKIDTKLFERLLKLWSKNATINEKYYQ
>NC_002745|775071:789712|788950_789712_+|WP_000616840.1|DBSCAN-SWA
MIQVENLTKTINNQMILEDISIDIEKGKLTSLIGPNGAGKSTLLSAICRLIRFDNGEVKIDGQLMSDYKNNDLSKKISILKQTNHTEMNITVEQLVNFGRFPYSKGRLTKEDHDIVNDALDLLQLQDIRNRNIKSLSGGQRQRAYIAMTIAQDTEYILLDEPLNNLDMKHAVQIMQTLKMLAHKMNKAIVIVLHDINFASCYSDQIVALKNGQLVKSDLKDNVIQSSVLSDLYDMNIQIEHIRNQRICLYFKD
>NC_002745|775071:789712|783109_783508_+|WP_000692521.1|DBSCAN-SWA
MKIIYFSFTGNVRRFIKRTELENTLEITAENCMEPVHEPFIIVTGTIGFGEVPEPVQSFLEVNHQYIRGVAASGNRNWGLNFAKAGRTISEEYNVPLLMKFELHGKNKDVIEFKNKVGNFNENHGREKVQSY

Homologous phage analysis in the prophage region

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000663030.1|775071_776130_+	histidinol-phosphate transaminase	A0A1X6WGT4	Pacmanvirus	7.9e-22	26.7
WP_000197262.1|776468_777011_+	5'-3'-deoxyribonucleotidase	NA	NA	NA	NA
WP_000429006.1|777889_778807_-	diacylglycerol kinase family lipid kinase	A0A1V0SBJ0	Catovirus	2.1e-07	22.0
WP_031760357.1|778897_778999_+	hypothetical protein	NA	NA	NA	NA
WP_000193751.1|779076_780582_-	peptide MFS transporter	A0A0P0IY73	Acinetobacter_phage	2.0e-58	32.2
WP_000930014.1|780922_781423_-	NADPH-dependent 7-cyano-7-deazaguanine reductase QueF	E7DN65	Pneumococcus_phage	5.9e-52	71.5
WP_001068501.1|781442_782309_-	DMT family transporter	NA	NA	NA	NA
WP_000692521.1|783109_783508_+	class Ib ribonucleoside-diphosphate reductase assembly flavoprotein NrdI	A0A2H4J545	uncultured_Caudovirales_phage	1.2e-52	72.0
WP_000855514.1|783470_785576_+	class 1b ribonucleoside-diphosphate reductase subunit alpha	A0A2H4J2N6	uncultured_Caudovirales_phage	0.0e+00	91.7
WP_000562498.1|785693_786665_+	class 1b ribonucleoside-diphosphate reductase subunit beta	A0A2H4J4P3	uncultured_Caudovirales_phage	4.2e-171	91.3
WP_000499195.1|786845_787001_+	hypothetical protein	NA	NA	NA	NA
WP_000876318.1|787039_788011_+	ABC transporter permease	A0A2H4IY97	uncultured_Caudovirales_phage	4.3e-139	78.9
WP_001245577.1|787997_788954_+	iron chelate uptake ABC transporter family permease subunit	A0A2H4J116	uncultured_Caudovirales_phage	1.2e-05	57.8
WP_000616840.1|788950_789712_+	ABC transporter ATP-binding protein	Q9EMR9	Amsacta_moorei_entomopoxvirus	6.5e-18	31.6

Sequences of DBSCAN-SWA_3

Nucleotide sequences of DBSCAN-SWA_3

>NC_002745|1668253:1677296|DBSCAN-SWA
ATTATTCGTCGTATGAGATTAAACTCATAACATCGTAATCTTTAATTTTTTCAATACCATTTAAATATTTCAATTCAATTATAAATGCAATACCTACTACGATACCGCCTAATTTTTCAACTAATTTTATTGCTGCTTCAATCGTACCACCAGTAGCTAATAAATCATCTGTAATTAACACACGTTGACCTGGTTTAATTGCATCTTTGTGCATTGTTAAAACATTTGTACCATATTCTAGGTCATACTCATAACGAATGACTTCACGAGGTAATTTCCCTTCTTTTCTAACAGGTGCAAAGCCAATCCCCATTGAATAAGCTACAGGACAGCCAATGATAAAGCCACGCGCTTCAGGTCCTACAACGATATCAACATCTCTGTCTTTTGCGTATTCTACAATTTTATCTGTTGCATAGCCATATGCTTCACCATTATCCATAATTGTAGTAATATCCTTGAAACTAACACCTGGTTTCGGCCAATCTTGAACTTCTGATACGTATTGCTTTAAATCCATTAATATTTCCTCCTAAATTGCTCACGACAATTGTGACTTTATCCAATTTTTTATTTCTGAAAAATCTTGATATAATAATTGCTTTTCAACATCCATACGTTGTTGTCTTAATTGATATACTTTGCTGGAATCAATCGATCTTTTATCAGGTTGTTGATTGATTCGAATTAAACCATCTTCTTGTGTTACAAATTTTAAGTCTAAGAAAACTTTCAACATGAATTTAAGTGTATCTGGTTTCACACTTAAATGTTGACACAATAACATACCCTCTTTCTGGATATTTGTTTCTTGTTTAGTTATTAATGCTTTATAACACTTTTTAAAAATATCCATATTAGGTATACCATCGAAGTAAATCGAATGATTATGTTGCAAAACTATATAAAGTTGAGAAAATTGCAGTTGTTGCAAGGAATTAGACAAGTCTTCCATTGACGTTGGTAAATCTCTTAATACTACTTTATCAGTTTGTTGTTTAATTTCTTCACCATAATAATATTCATTCGCATTTACTTTATCACTTTTAGGATGAATAAGCACGACAATATTTTCATCATTTTCTGTAAAAGGTAAACTTTTTCGCTTACTTCTATAATCTAATATTTGCTGTTCATTCATCGCAATATCTTGAATAATTAATTGCGGTGATTGATTACCATTCCATTCGTTGATTTGAACAGATCCTAATATATTAATTGGCTGTTCATCTTGTAACTCAGGTTCTAAGTGTCCATTTTGCCAAAATAGCGCGGCGATATTACTTTCACCAAGTGTCAATTTTAGATGATTTTTTTGTTGACCGATCGCCTTAACTGAAGAAACTGATAAATCATCCATTTCAAAAATAGGTCTAGAAAAATCTGTTCCGAAGGGTCTTAAACGATTCATATCACGAATATTTTTAATCGTTATATCATTTTCTGTTAATAATACGTCTACTGGCTTTACGGGATCTAACGAAGTTGTTTTAGATAATTCTTTCATCCATTTATTTAAACCTTCAGCTAACGATTCTATATTTTCAATATCCATCGTCATACCTGCAGCCATATGATGGCCGCCAAATTTAGCGATTAACTCTTGATGTGCTGATAGTATTTCAAACATCGACACTTGATCAATTGATCTGGCGGAACCTTTTGCATGATTTTGCTCCCTATCAATATTTAAAATTAATGTTGGCAAAGCAAATGTTTCGACAATTTTCGAAGCAACAATACCTAAGACACCTTCATGCCAATTTTCTTTTGCTAAAAGTAAAAATAAATCTCCCTTTTTAACTTTCGTTTCTGCCATAGCCATTGCTTCTTCTGTGATAGTTGCTACAATATCTTTTCTTTCACGGTTAAAATGTTCAACTTGTTCTGCTAAAAATGCAGCTTCTTCTTCGTCGTCAGTCATCAACAATTCGCAAGCTAATGATGCGTCATCTAAACGACCTACAGCATTAAGTCTAGGTCCAATAATAAAACCAATTGTTTCTTCATCAATATTGTCATTGTATCCCGCTTCTTTTAGCAATGCTTTAACAGAGGTCGGACATTGATCATTTAAGACTTTTAATCCTTGTTTCACTAATGATCGATTTTCATCAGTTAAGGATACTAAATCCGCAATGGTACCTATCGCAACTAATGCTTTAAAATAATCAGGTACATTTTCAATCAATGCTTGTGCTAATTTGTATGCAACACCTGCACCACACAATTGTTGGAACGGATAATTAAACGATGGATGCATTGGATGTACGATTGCATATGCTTCTGGTAATGTACTACCAATTTCATGATGATCAGTTACAATGACATCAACTCCTAAATCTTGAACCATTTTAATTTCATTATGACCTTGTATGCCATTATCAACAGTTATGATTAATGTTATGCCTTCATCATGAGCATTTCTAAATGCTAGTTCGTTTGGTCCATATCCTTCGGTAAAGCGGTTAGGAATATGCCATCCTACTTGTGCACCTAAAAGTTGTAATGTTGTCACTAAAATTGTAGTTGAGGTAACACCGTCGGCATCGTAATCACCATAAACTAGGATTTTCTCATCATTCGCTATCGCTCTTTTAATTCTTTCAATAGCCTTAGTCATATCGCTCAATTGCAATGCATCATGATTGACATCTGTGTCTGAAATGATGGATTCAATTGCTTGTTCATCAATAATCGATTTACTTTCTAATATTTTTTTTACGATTGGCGTTAACTTTAATTTTGATGTTAATTCATCACTTATGTATTCAGCTGGTTTAGTTAATTTCCACTTATACTTCGGTTTAATCATATATATTTACGCCTCATTTCCAAAAGACATTATATCTAAAATTACTTTAAATAAAAAGCACTTATCTAAATAATCAAGACTTTAATTATACCATTTTTTAAAAATGAATGCGGGAACTTATTTATATATATTTTGTTAAATTTAAATAAAGTAAAAAGCGGTATGTGAACTCTTTATTGTTTCACATACCGCTTAATTCATTTTAAACTAAAATCTTTTCATCGTTCGATTTCTTTTCTTTATATACAACTAATTTGTGTTTCGGCGATTTTTTCAACTGACGTTTTTTCATTATTCCCCATAGCGGAACGGCAATGAAGATTGAAGAGAATACACCAGAAATCAATCCGATAAATAATGCTAAAGTAAAGTTGAATATCGTAGGAGCACCGAAGAATAGTATAGCAACTACTACTACAATAACTGTTAATACTGTATTAATTGAACGTGTCATTGTCTGTCTAATTGATCTATTAACGATATCATCAATTTGTTCTGTTGTCGTAATCACTTTAACCTTTTGTAAGTTTTCACGTACACGGTCAAACGTTACGATTGTATCATTAATTGAATAACCGACAATTGTTAATACAGCGGCGATAAATGTTAAATCTACTTCAATTCTAAATAAACTGAAAATCGCTACTATAATGAATACATCATGTAATAATGCCAATACAGATGAAAGACCCATGCGCCATTCAAATCGTAATGATACATAGATGATGATACCTATCGATGCATAGATTAATGCAAGCATTGCATTTTTTGCTAATTCCTGTCCAATAATTGGTGATACAGTATTAATTTGAGGTGTGTCACCGAATTTCGATTTAATATTATCACTCAATTTATTATCTTGAGCACGCGTTAAATCGTCTTTAAATTGAACAGTTGCTACTTTATTATCTTTACCATTGATTTGAATTTGATCCGCTTTAAGTCCACTATCTTTTACAACTTGCTCAACCTTTTGTTGAGTAATTGCTTGTTTAGATTGGAAATCTACACGTGTACCACTTGAGAAATCAATTCCTAAGTTTAACTTGAAGATATAAAGAATAACTAAACCGACAACTACAATTAAAATACTTACTCCAATTAATGGCTTAGCTAATTTAACAAAATTCCATTTCTCGAATGAAGTTTTAAGGTCATGAACATCTACACCTTCATTAATATCATGTCGTTTATTCTTTTTAACACCAAATAACCAAAATTGATTTTTGAATATATTTGATGAAACAAGTAATGATAATAAGAATCTTGATAAGAACACGGCTGTAACAAAGATCATTAGAATACCTAATAATAACATTGTCGCGAAACCTTTAACTGAACTTTCACCGAAGAAGAATAATACTGCTGCGGCGATAACTGTTGTTAAGTTAGAATCAAAAATTGTTAGGAATGAACTTTTGTTTGCTTTAGAAAAGGCTTGCTTTATCGTTCTACCTATTCGAAGTTCATCCTTAATACGCTCATACATGATAATATTGGCATCTACAGCCATACCTACACCTAATACCAACGCCGCTAATCCTGGTAAAGTTAGAACCCCGGAAATGAAATTAAATGCTACTAACGTTAGATAGATATAAGTTGTCAATGCAATAATCGCTACTAAACCAGGTAATCGGTAGAATCCAAGCATGAATAAATAAATTAATGCTACACCAATAAACGATGCAAACACAGTTTTATCTAATGCATCTTGACCAAATTGGGCACCTACTGAGTTTGAATAAATTTCTTTCAAGTCAACTGGTAAAGAACCTGCATTTAACAATTCGGCGATTTGTTTTGCTTTTTTAACGCCTTCTTGTCCTTTAAATCCACCCGAGATTTCTACGCTATCAGAATTGATTGGTTGATCAACACTTGCTGCAGAAATAAATTTAGGGTTTTTCTTTTGTGCTTCTTTTTTATAGCTGTCACCTTTTTTGAAATCTAACCAAACAACCATGACATTATCACGTTTCTTAGAGATTTCTTCCGTTACTTTTTTAAATTTGTTTTTGTCTTTTACTTTAAAAGTAACTGTAGGCTGGTTTGTTTCCTGTTTAAATTCTTGTTTGGCAGATCCCTGTTTAATATCAGAACCGCTTAATTTTACTTTATCTTCTGCATCGCGAATTGTTAAATTAGCTTGAGAAGATAAAATTTTACGTGCTTCATTCTGGTCTGTTACACCAGCAAGTTGAACTCTAATTCTATTAGGTTCTTCAACTTGAATTTTAGGTTCCGAAACACCTAAAACGTTAACACGATTTTCTAATGTTTGCGCTGTTGATTGTAAGGCTTTTTTATCTATTTTGTCGCCTTTATTTAAAGGATCGACTTGATAAAGCACCTCAAATCCACCTTGCAAATCAAGTCCTAAATTGACATTCTTTATAACACTTTTATAAGTTGCAGCCATTCCGGCAAACAACAATACGACTAAAAGCAAGAACGCAATTATTCTACTACTTTTCTTCACATGAACACCTCATTATTTACGTATGTATTTAGAATACTTGAATACTATTTTATAACGCAAGTTAAATCTTTCTTACAAAATTTATTAGCCTTATACATATTAACATACTAGAGCAGGGAGTAAAAATAGTCATAGATATATTTAATTTAAATTTAACAATTATTATGTATCACAATTTCTTTTTTTGGAATAAAAATAAGCTATTCTACATACTACTTATAACTTAAAAAGGATGAAACGCTATTCGTTTCATCCTTTTTAATACCACTTCTCGTTATGAAGGGTCAACTTGTTTAATAGCAGGTTTTTCGAAAGTTAATTCAGTACCATGACCATTAACTGTAATAACAACAGTTGTTTCATCTACTGCTTTAACAGTACCTTTAATACCACCAATAGTTGTAATTCTTTGACCAGATTGAATGTTATTAATCAACTCACGATGCTGTTTCGCACGTTTTTGTTGTGGTCTGATCATCAAGAAATACATAACCGCAAAAATTACGACTATATATATTAGTAATGAAAATTGCATTTTATACGCTCCTCTTGCTTAAAAGTTTTTTGGGTTCTCAACATTTAATCCATATTGCTCGAAGAATTCTTCTTTGAAATCTAAAAGACGATCTTCTCGAATGGCTTGTCTTATATCTTCCATTAATTTTAGCAGAAAATGTAAATTATGAATAGTAGTAAGACGAATACCAAAAGTTTCCTCTGCCTTGATTAAATGACGTATATACGCTCTTGAATAGTTTTGACATGTATAACAGTCACAATTCTCATCTAACGGTCTTAAATCATCTGCAAATTTTGCATTTTTAATAACTAAACGACCTTGCGATGTCATACAAGTACCATTTCTGGCAATACGTGTCGGTAAGACACAATCAAACATATCCATGCCGCGAATACTACATTCGATTAACGCATCTGGAGATCCTACACCCATTAAATATCTTGGTTTATCTTTAGGCATAAACTGCTCTGTATGTTCAACCATTTTATACATAACCGGTTTAGGTTCACCAACTGACAAACCGCCGATTGCATAACCAGGAAAATCTAATTCTACTAAATCCTTTGCACTTTGTTCTCTTAAATCTTCATATTCGCCACCTTGTATAATGCCGAACAATGCTTGATCTTCAGGTCTTTGGTGTGCATCTAGACATCTTTTCGCCCAACGTGTTGTACGTTCAATAGATTTTTTTACATAATCATATTCAGCAGGCATCGGTGGACATTCATCAAATGCCATCATAATATCAGATCCTAAATCATTTTGAATTTGCATTGATTTCTCAGGACTCAAAAATAATTTAGACCCATTAGTATGATGTCTAAATTCCACGCCTTCTTCTGTAATTTTACGTAAATTACTTAAACTAAACACTTGGAAACCGCCTGAATCTGTAAGAATCGGACCATCCCAATTCATGAATTTATGTAATCCCCCAGCGTGTTTGATAATATCATTTCCGGGTTGTAACCACAAATGATATGTGTTGCCCAAAATGATTTTTGCTTCAATTTGTCTTAACTCTTCTGGACTCATTGTTTTAACGGTTGCTTTAGTACCAACTGGCATAAACATAGGTGTTTCAAATGAACCGTGTGGTGTGTGCACGATACCTAAACGCGCACCTGATTGTTTACAAGTTTTAATGTGTTCGTATGTTACTGCAGGCATATTCAAAATCCTCACATTCTTTTTATATAATTAACATTGCATCGCCAAAACTAAAGAATCTATATTCTAAATTTACTGCTGTTTTATAAGCATTCAGAACATTTTCACGAGTACTAAACGCTGATACTAGCATAACTAATGTTGATTTTGGTAAATGAAAATTAGTAATCTGGCCATCAATTGCTTTAAAATCAAATCCTGGATAAATAAATATATTAGTCCAGCCACTCGTTTCAACAAATTTATCATGATCGCGTCGAATTGTTTCAAGTGTACGTGTTGAAGTTGTACCAACTGATATAATGCGATGTCCTTTGGACTTAGTATCATTTAATAAATCAGCTGTTTCTTGTGTCATTTGATAATATTCACTATGCATTTCGTGGTCATTCACATCATCGACGCTCACCGGTCTAAACGTACCTAACCCAACATGTAATGTAACAAATGCGATATTAACGCCTTTATTTTTAATTTCAGTTAATAACTCATCAGTAAAATGTAATCCTGCTGTTGGTGCTGCCGCTGAACCACTTTCTTTAGCGTAAACTGTTTGATAACGATCTGGATCATCTAAACGTTCTTTGATGTATGGTGGCAGTGGCATTTCCCCTAATTCATCTAATCTTTCTTGTAAAATACCTTCATAATGTAAACGCATGATGCGTCCACCTTGATCCATTTCTTTTATGCACTCAGCTATAATTTTGCCATTACCAAAATTCAATTTATTACCAACTTTAATACGCTTAGCTGGTTTCAGTAAGACTTCCCAATCATTACCTTCAATTTGAGTTAACATTAACATTTCAACTTTTGCACCAGTTTCTTCTTTTAAACCAAAAAGTCTAGCTGGCATTACTCGCGTATCGTTAAGCACTAATGTATCACCAGGTCTAAAATACTCAATGATATCTTTGAAATGTAAATGTTTCATTTCACCAGTTTCTCTATCCATGACTAATAAACGACTATGATCACGATCTTTTAAAGGCGTTTGAGCAATTAATGATTCTGGTAAGTCATAGTCAAATTCTTCAATATTCACGTTATCCTCTCTCCTCATTCGACTTTGCAAAATGTTCATAAGCTAATGGTGTTGCTTTTCTGCCACGTGGCGTACGTTCTAAAAAGCCTTTCTGAATAAGAAATGGCTCATAAACGTCCTCAATTGTAATACGTTCTTCACCAATTGTTACGGCAATCGTATCTAAACCAACAGGTCCACCATTATACTGCTTAATAATACAGTTCATCATTTTATGATCAATGTAATCTAGTCCGTGTTGATCAACTTGAAGTAAACCTAATGCGTGCTTCGTTGTTTCAATGTATATTTGTTCATCTTCATTCACTTGCTGGAAGTCTCTTACCCGCTTCAATAGTCGATTTGCTACTCTTGGAGTCCCTCTAGAACGTTTAGCAAGTTCAATGGCACTTTCTTCATCAATACCTGTGCCTAAAACCTCAGCTGTTCTAATAATGATTTCTTTTAAATCTGATTCATTATAATATTCTAATCTTAAGTGCACACCAAATCGATCCCTTAGTGGACCTGTTAAGCTGCCAGCTCGCGTTGTTGCACCTACCAAAGTGAATGGAGGTAAGTCGATACGGATACTTCTAGCCTCATCGCCTTTACCAATGATAATATCTAAAAAGAAATCTTCCATTGCAGGGTATAACACTTCTTCAACAACACTACTCAGTCTGTGTATTTCATCAATAAACAATACATCTCCAGGTTGAAGTCCTGATAAAATTGCAGCCAAATCACCAGGTCTTTCTAATGAAGGCCCTGATACTGTACGTATATTAACTTCCATTTCATTGGCAATGATATTAGATAATGTTGTCTTACCTAATCCAGGGGGGCCAAAAAGCAATACATGATCTAATGGTTCATGACGAAGTTTAGCCGCTTTAATAAATACTTCTAAATTACTTTTTATTGAATTTTGACCAATATATTGTCGTAATCTCGTAGGTCTAAGCGACAATTCGAAATCAGTTTCTTCACTATGCATTGATTGATCAACCATACGCTCATTCAT

Protein sequences of DBSCAN-SWA_3

>NC_002745|1668253:1677296|1673823_1674084_-|WP_001160682.1|DBSCAN-SWA
MQFSLLIYIVVIFAVMYFLMIRPQQKRAKQHRELINNIQSGQRITTIGGIKGTVKAVDETTVVITVNGHGTELTFEKPAIKQVDPS
>NC_002745|1668253:1677296|1675264_1676290_-|WP_001019178.1|tRNA|DBSCAN-SWA
MNIEEFDYDLPESLIAQTPLKDRDHSRLLVMDRETGEMKHLHFKDIIEYFRPGDTLVLNDTRVMPARLFGLKEETGAKVEMLMLTQIEGNDWEVLLKPAKRIKVGNKLNFGNGKIIAECIKEMDQGGRIMRLHYEGILQERLDELGEMPLPPYIKERLDDPDRYQTVYAKESGSAAAPTAGLHFTDELLTEIKNKGVNIAFVTLHVGLGTFRPVSVDDVNDHEMHSEYYQMTQETADLLNDTKSKGHRIISVGTTSTRTLETIRRDHDKFVETSGWTNIFIYPGFDFKAIDGQITNFHLPKSTLVMLVSAFSTRENVLNAYKTAVNLEYRFFSFGDAMLII
>NC_002745|1668253:1677296|1668793_1671067_-|WP_000595011.1|DBSCAN-SWA
MIKPKYKWKLTKPAEYISDELTSKLKLTPIVKKILESKSIIDEQAIESIISDTDVNHDALQLSDMTKAIERIKRAIANDEKILVYGDYDADGVTSTTILVTTLQLLGAQVGWHIPNRFTEGYGPNELAFRNAHDEGITLIITVDNGIQGHNEIKMVQDLGVDVIVTDHHEIGSTLPEAYAIVHPMHPSFNYPFQQLCGAGVAYKLAQALIENVPDYFKALVAIGTIADLVSLTDENRSLVKQGLKVLNDQCPTSVKALLKEAGYNDNIDEETIGFIIGPRLNAVGRLDDASLACELLMTDDEEEAAFLAEQVEHFNRERKDIVATITEEAMAMAETKVKKGDLFLLLAKENWHEGVLGIVASKIVETFALPTLILNIDREQNHAKGSARSIDQVSMFEILSAHQELIAKFGGHHMAAGMTMDIENIESLAEGLNKWMKELSKTTSLDPVKPVDVLLTENDITIKNIRDMNRLRPFGTDFSRPIFEMDDLSVSSVKAIGQQKNHLKLTLGESNIAALFWQNGHLEPELQDEQPINILGSVQINEWNGNQSPQLIIQDIAMNEQQILDYRSKRKSLPFTENDENIVVLIHPKSDKVNANEYYYGEEIKQQTDKVVLRDLPTSMEDLSNSLQQLQFSQLYIVLQHNHSIYFDGIPNMDIFKKCYKALITKQETNIQKEGMLLCQHLSVKPDTLKFMLKVFLDLKFVTQEDGLIRINQQPDKRSIDSSKVYQLRQQRMDVEKQLLYQDFSEIKNWIKSQLS
>NC_002745|1668253:1677296|1674102_1675242_-|WP_001112045.1|tRNA|DBSCAN-SWA
MPAVTYEHIKTCKQSGARLGIVHTPHGSFETPMFMPVGTKATVKTMSPEELRQIEAKIILGNTYHLWLQPGNDIIKHAGGLHKFMNWDGPILTDSGGFQVFSLSNLRKITEEGVEFRHHTNGSKLFLSPEKSMQIQNDLGSDIMMAFDECPPMPAEYDYVKKSIERTTRWAKRCLDAHQRPEDQALFGIIQGGEYEDLREQSAKDLVELDFPGYAIGGLSVGEPKPVMYKMVEHTEQFMPKDKPRYLMGVGSPDALIECSIRGMDMFDCVLPTRIARNGTCMTSQGRLVIKNAKFADDLRPLDENCDCYTCQNYSRAYIRHLIKAEETFGIRLTTIHNLHFLLKLMEDIRQAIREDRLLDFKEEFFEQYGLNVENPKNF
>NC_002745|1668253:1677296|1668253_1668772_-|WP_000364542.1|DBSCAN-SWA
MDLKQYVSEVQDWPKPGVSFKDITTIMDNGEAYGYATDKIVEYAKDRDVDIVVGPEARGFIIGCPVAYSMGIGFAPVRKEGKLPREVIRYEYDLEYGTNVLTMHKDAIKPGQRVLITDDLLATGGTIEAAIKLVEKLGGIVVGIAFIIELKYLNGIEKIKDYDVMSLISYDE
>NC_002745|1668253:1677296|1676291_1677296_-|WP_001005768.1|DBSCAN-SWA
MNERMVDQSMHSEETDFELSLRPTRLRQYIGQNSIKSNLEVFIKAAKLRHEPLDHVLLFGPPGLGKTTLSNIIANEMEVNIRTVSGPSLERPGDLAAILSGLQPGDVLFIDEIHRLSSVVEEVLYPAMEDFFLDIIIGKGDEARSIRIDLPPFTLVGATTRAGSLTGPLRDRFGVHLRLEYYNESDLKEIIIRTAEVLGTGIDEESAIELAKRSRGTPRVANRLLKRVRDFQQVNEDEQIYIETTKHALGLLQVDQHGLDYIDHKMMNCIIKQYNGGPVGLDTIAVTIGEERITIEDVYEPFLIQKGFLERTPRGRKATPLAYEHFAKSNEERG
>NC_002745|1668253:1677296|1671269_1673549_-|WP_000749795.1|DBSCAN-SWA
MKKSSRIIAFLLLVVLLFAGMAATYKSVIKNVNLGLDLQGGFEVLYQVDPLNKGDKIDKKALQSTAQTLENRVNVLGVSEPKIQVEEPNRIRVQLAGVTDQNEARKILSSQANLTIRDAEDKVKLSGSDIKQGSAKQEFKQETNQPTVTFKVKDKNKFKKVTEEISKKRDNVMVVWLDFKKGDSYKKEAQKKNPKFISAASVDQPINSDSVEISGGFKGQEGVKKAKQIAELLNAGSLPVDLKEIYSNSVGAQFGQDALDKTVFASFIGVALIYLFMLGFYRLPGLVAIIALTTYIYLTLVAFNFISGVLTLPGLAALVLGVGMAVDANIIMYERIKDELRIGRTIKQAFSKANKSSFLTIFDSNLTTVIAAAVLFFFGESSVKGFATMLLLGILMIFVTAVFLSRFLLSLLVSSNIFKNQFWLFGVKKNKRHDINEGVDVHDLKTSFEKWNFVKLAKPLIGVSILIVVVGLVILYIFKLNLGIDFSSGTRVDFQSKQAITQQKVEQVVKDSGLKADQIQINGKDNKVATVQFKDDLTRAQDNKLSDNIKSKFGDTPQINTVSPIIGQELAKNAMLALIYASIGIIIYVSLRFEWRMGLSSVLALLHDVFIIVAIFSLFRIEVDLTFIAAVLTIVGYSINDTIVTFDRVRENLQKVKVITTTEQIDDIVNRSIRQTMTRSINTVLTVIVVVVAILFFGAPTIFNFTLALFIGLISGVFSSIFIAVPLWGIMKKRQLKKSPKHKLVVYKEKKSNDEKILV

Homologous phage analysis in the prophage region

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000364542.1|1668253_1668772_-	adenine phosphoribosyltransferase	A0A1V0SKE5	Klosneuvirus	5.6e-29	46.5
WP_000595011.1|1668793_1671067_-	single-stranded-DNA-specific exonuclease RecJ	A7KV88	Bacillus_phage	8.1e-64	29.3
WP_000749795.1|1671269_1673549_-	protein translocase subunit SecDF	A0A1B1IVP7	uncultured_Mediterranean_phage	1.8e-31	35.8
WP_001160682.1|1673823_1674084_-	preprotein translocase subunit YajC	A0A1B1IVR5	uncultured_Mediterranean_phage	8.2e-05	35.3
WP_001112045.1|1674102_1675242_-|tRNA	tRNA guanosine(34) transglycosylase Tgt	A0A1B1IVQ4	uncultured_Mediterranean_phage	5.4e-85	44.7
WP_001019178.1|1675264_1676290_-|tRNA	tRNA preQ1(34) S-adenosylmethionine ribosyltransferase-isomerase QueA	NA	NA	NA	NA
WP_001005768.1|1676291_1677296_-	Holliday junction branch migration DNA helicase RuvB	B3GAM6	uncultured_virus	1.7e-05	29.1

Sequences of DBSCAN-SWA_4

Nucleotide sequences of DBSCAN-SWA_4

>NC_002745|1808959:1866661|DBSCAN-SWA
ATTATGATTCTTTTTCGTTTTTAGTACGTCTTCTAGCTAACAAAGCCGCACCTGTAATCAGTGCAAATTCTTTCAATGGTAAATCCATTCCTTCAGAACCTGTATTTGGAAGTTCTTTTTCAACTTTGCGCGATTCATGTGTCTCTTCTTTTTTAATAGGCGTACAAACTTTTGGAGCTGGCTGAATTTCTTTTGGTGATACTTTCGTCGCTTCAGCTGGTAATTTAATTGCTAAAATTTCATCAACAATGAATTGCGTGTGTTGTTTGATGTCATTTAATGTCGCATCTTCATCAATCATTCTATTGCCATCTGCAACATATTGATCAATTAATACTTTTACTTTAGCTAATTGTTCTGGTGTTGCGATCGCTTTGAATTTCGCATATGTTTGTTGAGCAATGTTATCAATTCGCAGTAAGCTATTTTCTTTTTCAGTAATTACTGCTTCTATATCGCTTAATGCAACATTAAATCGTTTTAAAACTGCATCAACATCAGCATTAGTGCGTGCTGTTTTTAATTCTTCATCCATTTGTAATTTTAAAGCAGTTATAGCTTTTAATGCATCAGCCTTATTACGATTACTTACTTTTCGATAATTTTGCACTAAAGCAGTGACGCGTGCAAGATCATCATTAATCGTTTTTTCAGCATCTGGCTTTTTAATAGGATGTACATCTAAATCATGTATTGTTTGTAGATTTAATGATGCTGTTTTATCAACTTGTGCATTGCTACGATCTTGATCAATTTGTCCAATAGCAGTGTCATAAATATTTTGTAACTGTGCTAATATACTATTTCTTTCTTCTACCGTTGCTTGAATATTCGCTTCAATTGCTTGTTTTTTATCGTTGAATAATGTTGTCAATTGTTCTCGAGCAGACGCCTTTCTGTTAATAACAGGTTCGATTTCACGAATTTCGTTTTTCTCATCATGCAATAAATATGCCACATCAGCATTAGTCACTGCACTAGCAATTTGTTGTTTAGCTTTAATTAACTCTTTTTCAACTTGTGCTATTGCAATATTTTGTTCTTCATCTGTCGCTTCGTTATTTGCTTTAATTAAATTAATTTTATTTGTAGCGATATTTTGAATTTGTTGTAATGCTGTTGCTTTAACTGTTGTCGCTGGTTTAATTTTTGAAATAATATTTTGAGCATCTATACTATCTTGATTAACTTGGGCAGTCTTATCTGCATGATTGATCTGATCAATAGCCTGATTAAGTGCTTGTTCTACTAAATGTTTAGCAGCTAGTCTTTCTTCTTCAGTTGATAAATCGCTTTGATCGATTAGTGCATTTTGAGCTTCGGCTTTTACACCAACAGATTGACGCGCTGCTGGTTTAACTTGAACTTTAGGTAAAATCACTTTGATGTTGTCGTTGCCATCAGTCTCAGTTCGATCCACTTCTGCATTCGTTTTGTTTTGTGCAATGTCATTTTTAATTGTATTTACAATTTTATTTAAAGTATCAATAGCAACATCTCTTTCATCTTGAGTAGTATCCAACGTATTTCGGATTGCATCGAGTTGATTTTTATTATTTTCTTCAATGCTATCAAGCGCAGCTCGTTTACGTCTTACTTTAGGTTTTATTTGCTCAATTGCCTTGATTGTTTGATTTCTAACATCAGTAACAGCAGCATCTTGATTTGTATTTTCTATTTCTTGTTGCGCTTGTTTGAGTGTGTCGCTAATTAATTGATTCGCTTCATCTAATTCATCAACTGTTGCATGTGGTGTATCTTTTATTGATTCTACTTGATTTTCTGCAGTTGCTTTTATTGCTTGTTGTGCTTCAGGCTTAATTACAATATGAGGTTGTACACCTTTTAGTGTAGCAATGCCATTTGTTTCAACACGTTTCACATCATTATTCGTTACTGCTTGATTGATGTTTTGTAATGCAAGTTTTTCATTATTCGCTAATTGATTTAAAGCAACTTGTTTTTCTTCATCAGTCGCATGTTCAGCTTGCTCTATTTCTTGCTTTTTAGCCTCATATTGTTGCTTTACTGCATCTCTAGCAGCTGCTCTAACAATATGTTCAGGCGCTACTAAAGCAATGCTATCAAGCGCTTGACTTGTTGTATCATCAACTTGTTGATTTGTTCTATTATTCGTAATATCTGTCATGGCTTGATTTACAAATTCATTGATTTTATCTAGTGCTACTTGTCTTTCTTCTGCTGTTGCTTCTTTATCCTGATTAATCTTAGCACGTAATTCATTCGCTTTTTGATTGATTTTTTCACGTGCAGCTGGTTTAACTTTTGTTTCAGGTTGAATAATTTTAATCGCTGATACACCATTTGTTGCTGCTTGATTCACCTGACTATTCGTTTGAGCTTGGTCAATAGCTGCAAGTGCTTTTTCTTTTTCTTTAGCTAATGCTTGTGAAGCAACTTCTTTCTCATTATCTGTTGAATCAAGACTATTATCAATTTGCTGTTGCTTTTCTTTAACAGCTTTTTCAATATCTGCAATTGCCTTTGGTTTAATTACTACTTCAGCTTCAACATTATCTATAGCATTTACCGCTTGATTTGTAGTTGTGTCTACCTGATCATTTGTTTGGTTTTGATTAATTTGATTAATTGCTTGATCTTTAAGTTGATTGATTTGATTAACAGCAGCCTGCTTTTCTTCGTCAGTTGCATTAGGTGTTTGTTTAACCGCTTCAATACGCTTCGCCACTTCAGCAGTGATTTTATCTCGCGCTGCTTGTTTTTTTACTACATCAACTTGAACAGCATCGATATTATTCTCTGCTACTGTCGCAGCTTGGTCTACTTCTGCATTTGTGTTAGCTTGTTTAATACTTTCAATAGCTTGTTGTCTGTCTTGATTTAAAGTATTGATCGCAGCATTTTTCTCATCATTCGTTGCATCTGGTGTAGCATTGATTTCAGCTAATTTAGCATTATAATGCTGATTGATTTGTGCTAATGCTGCAGGTTTTTTAACAATATTTGGCTGAATCGCATTAATTGCTTTTGTACCTAATTGTTGCGCTTGATCTACTTCCGCATTTGTATCAGCTTGATTTATATTATTAATTGCCGTTGCTAACTCTTGATCCACTTGATTTAAAGCCACTTGCTTTTCTTCAGTTGTTGCATTTGTGTTTTGATTAATTTCTTGCTTTTTAGCAGTTGCTAAATCATTTAATACACCTGTAGCAGTTTGTTTCTTCGTTACATGCGGTTGAACTGCGCCGATTTGATTGACTGCATCGTCTCTAATACTATTGACCATCGCAGTAGTAGACGTCACACCAATATCAGTTAATGCTCTATTTTTAAGTGTATTGACACGATTTATCGCTTCTTGTTTCTCTTCTCGAGTCGCGCCAGGTGTAGCATTGATATTTGTTATCGCCTCTCGAGCTTTATCATTTACAGCATTGCGAGCATCCGTTTTAACTTGTGTTGCCGGTTGAATCACAACTATATTTTGTGTGCCCTGATCTTTTGCTTGTGCAACTTCTTGATTCGTATCTGCTGCATTAATATTTTGCTTCGCTGTGGCTACAGCTTGATCAAGTAATTGTTGTGCTGCTTGTTGTTCTTCGAGCGTCGCATCATTATTATTAAATATCGTATTATGTTGCGTTTCCGCACTTTTATCGATGGCATTTTTTGCATCTGTTTTTACTTTTGTAGCTGGTGTAATTGCTTGTATTCCTTGAATCGCATTTGTCTTTACTTGTTCAACATCAGCATTGGTATTAGCGTTTAAAATGTTTGTGTTTGCTGCAGTTACAGCAGCATTCACTTTGTCAATTGCTGCTTGTCTTTCTTCTTGAGTCGCATCAGGATTAGCATTGATTTCTGCGATATGTTGTTGTGCATCATGTGATACAGCATCCCTTGCAGCTTGCTTAACAACAGTTACAGGAGCAATTGGATTAATGGCATTTAGACCATCTCCTTTGGCGTTATCAACATCAGCATTTGTTGTTGCTTGATTGATTTGTTCTAAAGCATGGTTGGTTGCTTGAGTTAATTCGTTCAATGCTGCATTTTTCTCTTCCTGAGTTGCTTCTCTATTACTATTTATTTGTTGTCTTTTCGTTGCTGTTGCTTGGTTAATTGCATCTCTTGCAGCTTGTTTATGTGTCACTTGAGGAACAACTGCTCCAATAGTATTGATGCCATTATTTTTAGCTATTTCAACGTCAGCATTTGTAGTAGCATTCGTAACATTATCAATAGCATCTGTTTCATCCGTAGCTAATTGATTTAGTGCATCTTGAATCTCGTCTTCAGTAGCATCTGGTGTTGCATTGATAATTTCCCTTTGTTTCGTTGCTTTATCACGTATTGCTTTTTTAGCATTTGGTTTAACAACCGGTGTTGCAGTATCCCCACTTAAGGTCTGTATACCTTGATCTTTGATTCTAGTAACGCCATCATCAGTCGTTTGGTCACCAATATTACCAATTATTTCATTTTTATGTTCCTCGATAACTTGTATTGCTGCTTGTTTTTCTTCATCTGTCAATTCATCATTTTGATTAACTAAATCTTCCATTTGGTCAACTTTTTTATTAACTGCATTTTCAGCATCAACACTTCGAATTAACGTATGTTGCATTTGATTAGTTAATGAATCAATATCTGCTTGAGAAACTCTTTTATTTAATGGTACATTGTTACGATTTTCATCTAAAATCGTTTGTGCACGTCTTTTAAGATCATTAAAGATATCTAATGATGCAAATGTATAATCAGCTTGTTGAATGCGTCTATCAACCTCGGCTTGTAATGCATCTTTATTCATGATGATATCGATTGTATATGGATTTGTACTTACAGTATGACTTTCAGCAGGTGAATTAATAAAATCTTGTGTATATGTTTTATATGTTAATGTATCATTAAATGTTACTGTTCTTGGTGTCGGTACATTATTAACACGCAACTTATACTTTAAATCCAATATTTTATCAGGCATTAATCGTGCCGGCGAGTTACCTGAACCTCCACCAGTACTTTTAATTGTTATCACTCGATTCGCCGCATCATACGTCACATTAAAATCATTCATATCAACACCTGAATTACTGCTTGGAAAATCTTTAGTCAATGAGTTATTAACATATTCTACCCCTTCAGGTAATTGAACTTTATATACAAAATCATCTGTATTAAATGAAGCACCGAAGTTACCATTATTCTTTAATGAAGTTGTGACTGTAAATTCTTTATTATTAGTAGCTGTGGGTTCCATTGTTCGTCTTTCAACATAGACATGCGAACCAGAATGTAGACCAATTGAGTCAACAAAGTCATAGTATTTATAACCGTCTCTTAGTTGATAAATGCCACGCGCATCTGTTATTGCATCATTTTTAGGTACAAATTGAATTTTTAAGTGACTAACATTTTCAGGCACTTTAAACAAACGCCAAATCGGACCATAAGCTACTGATTTTTCTGCAATAACAGTATCATTATCAGCATTTTTAATTATTAAATTTGTCACACCTTGATAGTTTTTTGTAGTCATCGTATTAAATTCGAAAATTAATTCAGAATTTGGATTTACTGTTAAAGATTTTTCAATTCCATTAAAATCACCATGATCATTTGTATCATTTCCCTTAATACGACCTAATGCAATTACATTTCCTTGTGCTTGATAGTTCTTAGCATCTCCTGAATCAAACATACTTGTTCTAACCATCGCATGACTAAACACACCTACTTTACCACCATTGATAAGTGTAAAGCCTGGTAAATTATCAACAACTGTTACTGATGGTACAGAACGGTTGGTACTTGGTCTAATACCATTGTCATCAAAAGACAGCACTTCGTTAGGTGCATTTTGTCCTGCATTATTGGCATTAGGATCAGTTGTCGGCGTGTATGGCGCTGTAATTGCTACTGGTGCACCACCGTTTCCTGCCGCTGCAGCCGCTGGATCTGCTGGAGTTGCATTAGGATCTGCCGGTGCCGCACGTCTACTTCTCTTTTTCGGTCTATTAGATGCTTGTTCAGCAATTGCAACTAGCTCTGGTTTATCTGAAGAATGACGAACATCTTCTTGAATTTCCTTTAAAGTTAGATGTCCTCCTGAACCATTTTCATTTGTTTTATTAGGTACATTTAATGTGGTATTATTCGACACTACATCCTTATTATTAGCGTTTGACACTGTCTCAGTTGCTGTTGTATTGCCATCTGTATGATTATTGTTTTGTGCTGAAGGCGTACTTGATTGCACTGATGTTGGCGTAGCTTGATTTGCTATACTACCATTATTATGATTAACCAATGCTTGATTCGTTGATTGATTAGTTGTTGCAGATTGATTAGGTGTATTCTGAGCACTATTTGCTAAACCTCTATTATTAGCAACATTTGTATCTTGTGAATTTACAGGTGTGGCTTGATTAGTATCGCTTTGTACATTATTATCCGTAGTTAAGGCTTGTGCACCATTTGGGTTTGAAAGTAATAAAACTGTTCCGATTAAAGTAGAGAATATGCCTACTTTATACTTCCTAATACTATATTTATTTTTCTTTAACAAATTCATTTCATTTTCCTCCTGGTTGTCTGTTCTCTGCTGTGTTGTTTAGAATTATGCTAAAAATATACGCTCTCTCATATTATGTTTATAGCTATATTATTTTGTACAATATTTTAAGTTCACTCAATTTTATCATCATCATTTTATAAAATAAAGTTTTATTTTATTACAATTTAGTTTCCGTTTTGTAATTAAAATCTTAATAAAACATAACAAGAACGCTTTAGATTGTTTTGTAACAGAAAGTAATTCATACCAAAAAACACCAAGCAACCGAAACGTTACTTGGTGTCATTACAAATGTAATATTATTTTAAATTATGTCACTACTTTAAATACTTTTTATTTCCAAACCTTCATCGCCCCATGCGTGCATGCCGCCTTCGACATTTACGGCATCAATGCCATTTGCCTCTAAATATTCTACAACTTTAGCGCTTCGAACTCCACCAGCACATACAATATAATATATTTCATTTTTATTAAATGAATTTAAATTATCCGGAATGGTATCCATTGGAATCAACTTTGCATTAGGAATATATCCCATTGCTGTTTCTTCGTCAGTACGAACATCAACAATTTGAACTGGTTTAGATTCAAAAAGTTTGTTTTTTAATTCATCTGTAGTAATTGACTTCATTTCAAAGTCCTCCTTAAAACATTATTTAGCTACAATATTGACTAATTTTTGAGGAACAGCGATGACTTTCATGATGTCTTTACCTTCAATACTCGCTTTAACATTGTCATTAGATAAGGCAATTTCTTGCATTTCTTCTTTTGATGTATCTTTAGCAATTTTAATTTTAGCTCTCAATTTACCATTTACTTGAACAACGATTTCTACTTCATCATCTACAAGTAGTGCTTCGTCATAAGTTGGCCAAGGTTGGTACGTAATAGACTCTTCATGTCCTAATTTTGACCATAATTCTTCACCGATATGTGGTGCAATAGGTGCTAACATTTTAACGAAGCCTTCAATGTAAGGTTTATAAACTTCATCAACTTTATAACACTCATTAATAAATACCATTAATTGACTAATAGCAGTATTAAATCCTAATGTTTCAAAGTCTTCTGTTACCTTTTTAACAGTTTGGTTATAAACTTTATCTAAAGATTTATTATTTGTAGTTACAATTTTTGAACTCAATGTTCCATCTTCATTTACCATTAAACGCCATACGCGATCTAAGAATCGACGAGACCCATCTAATCCTTTTTCACTCCATGCAATTGCAGCATCTAAAGGTCCCATAAACATTTCGTAAAGACGTAAAGTATCTGCACCATGAGACTGTACTATATCATCAGGATTGATTACATTTCCTTTAGATTTACTCATCTTCTCATTACCTTCTCCTAAAATCATACCTTGGTTAAATAATTTTTGGAAAGGTTCTTTAGTAGGTACGATACCCAAATCATAAAGGACTTTATGCCAAAATCTTGCATATAATAAGTGAAGAACCGCATGTTCTACTCCACCGATATATAAATCAACAGGTAACCAATGTTTTAATTTTTCAGGATCTGCTAACATATTTTCATTTTTAGGATCGATGTAACGTAAATAATACCAACAACTACCTGCCCATTGTGGCATTGTATTTGTTTCACGACGTCCTTTCATACCTGTTTTTTCATCTACAACATTTACAAATGAATCAATATTAGCTAGTGGAGACTCACCAGTCCCTGATGGCTTGATTTCATCTGTTTCAGGTAACAACAATGGTAGCTCTTCTTCAGGAACAGTTGTCATTGTTCCATCTTCCCAATGAATGACAGGAATTGGTTCGCCCCAATAACGCTGACGACTGAATAACCAATCTCTTAATTTGTAATTAACTTTCTTTTCGCCAGCACCTTTTTGCTCTAATAATTGAATAGCTTTAGTAATTGCCGCTTCATTTTCTAAACCATCAAGTTCACCAGAATTAATATGTTTACCTTCACCAGTGTATGCTGCTTCTTCAACATTTCCACCTTCGATGACTTCAATGATTGGCAAATCAAACTTTTTAGCAAATTCATAATCTCTGTCATCATGCGCTGGTACTGCCATAATTGCTCCAGTACCATATGTTGATAATACATAATCAGCAATCCAAATTTGTACTTTTTCACCAGATAAAGGATTAATTGCATATGCACCAGTAAACACACCTGATTTATCTTTTGCTAAATCTGTACGTTCTAAATCTGACTTTTTAGAAGCTTCTGTTTGATAAGCTTTTACTTTTTCTTTATATTCATCAGTTGTAATTGAATTAACTAATGCATGTTCAGGACTTAAGACTAAGAATGATGCACCATAGATAGTGTCTGGTCTAGTCGTAAATACTTCTACTTTTCCTTCCGTATTATCTACATCAAATGAAACTTTGGCCCCTTCAGAACGTCCAATCCAATTGCGCTGCATATCTTTTAAAGACTCAGGCCAATCTAAATCATCTAAATCTGCTAATAATTGATCTGCATATTCTGTGATTTTAAGTACCCATTGTTTCATCGGCTTACGATAAACTGGATGTCCACCACGTTCAGAGACACCATCAATCACTTCTTCGTTAGATAAAACAGTGCCTAATGCTGGACACCAGTTAACTGCAACTTCATCAACGTATGCTAAACCTTTGTTATATAACTGTATGAAAATCCACTGTGTCCATTTATAGTATTCTGGATCTGTTGTATTAACTTCACGATCCCAATCATAACTGAACCCTAATTCTTTAATTTGTCGTTTAAAAGTTTGGATATTTTTCTTTGTAAATTCACGTGGGTCGTTGCCAGTGTCTAAAGCATATTGCTCTGCTGGTAATCCGAATGCATCCCACCCCATCGGATGTAATACATTATAACCTTGCATCCTTTTATATCTTGAAATGATATCTGTTGCTGTATAGCCCTCAGGATGTCCAACATGTAAACCAGCACCTGATGGATATGGAAACATGTCTAAAGCATAAAATTTCTTTTGACCTAAGTTATCATTTGTTTTAAATGTTTTATTTTCGTCCCAATAGTCTTGCCATTTCTTTTCAATTTGATTGTGGTTGTAATTCAACACATTTCCTCCTATTCAATAAAAAAGACACCTCTAACTATTCTATTTACATAGGGACGACATTTGCCGCGTTACCACCCTATTTCACAAAAATTGTGCACTCATTTTAATAGTAAGAGATGTCATTCATTCAATTTAAAATTAATACGATTTACATTTAGTCCTTAACACTAGCTCTCAGCATCACTAGCTTTCTGTAGAAAAGCTCCAAACGAAATTAAATTATACAAATTAATATTATGTTATAACGACATTTATTTCAAGTCTATAACGTTAATTCTATTTACTCATTATGCATCTATTTTTTTAGGTTGCGTATTATTCTCCTTGAAAACCATTAATAATATTAATGCAAATACAAGTAGTAGCATCATACCGATAAACATCATGCGCATATTAAACGCATCAACTAATACACCACCAAGAAATGGACCAAATGCTTTTCCTACTGTAGCAGCTGAATTCACAAAACCTTGGTACTGTCCTTGCTTACCATCTGGCGCTAACTGATTGGCTATAGTTGGAACTGCTGGCCATACAAACATTTCTCCAAAAGTTAAAATAATCATACCGACAACAAATATTGTAAAGTTTTCGGCAAAACTCGTGACAAAGAACGACAACATAAAAATGATGATGCCGACAAACATTTGCTTCTTTAAGTTTCCTTTTAACAGATAGAGAACCGGTTTAATTAATGGTTGTGCTACTAAAATCATTATTCCGTTAATTGTCCATAAAACACTATATTGTGCCATTGAAATATTAATAGATTGTGTAAATGATGCGATTGTAGACTCCCATTGAATATACGCAACCCAACAAATTGCAAACATTGCACAAATTAGTACTAATGAAATAAATCTTGCTTTATTCTTTTTACCAGTAATATCTAAATGAGTTGGATATTTAACTTTCGCATTAATTTCAATATTAAATTGCGTTACCGCGACAAGCGCAAACACAACATACATAATAAGATTGGCTAAAAAGATATAGTTAAAGCTAAATTCTGCGACAAAGCCGCCCATTGCAGCACCGACAGCCACACCAATATTTTGCGCTAAGTATATCGCATTAAACGTTTGTCTTCCGCCATTCGGCCACACTGCTCCAGCCATAGCGTATATCGCAGGAATAATCATTCCGCCACCAAAGCCTAACATTACAAGCCATACAGCATACCAAGGCCACCCGTGAAAGAAATTAAGTAGCGTTGTACTACAAAGACAAGTGAAAGTTCCAATTAAAATCGTCTTGTATCCACCTAATTTATCAAATAGTGAACCACCTAATAAGTTTCCAATAACCATGCCAAATGAATTTATCATTAGCACTAAACCAGCAACAGTTAAACTTTTTCCAAGTTCTTGTTTCATATAAATTGTATTTAAAGGCCACAAAAAACTGGAACCAGTAATATTTAACGCCATGCCAATTACTAGCCACCAGACTGATTTAGGTATATTCATATTTCATAGTTCCTCTCTCTTTTTTGTCAAACTATAATAAACACTATAACATTAAAATATGTTAAAATCTGTACTTAGAACTCTTTTTTTATAGAAAGGAAAATGACATATGGGCAATCATTTCCAATACGCTTTTGAAAACAAACGTTATCACACATGGAATTACCATTTAAAAAATAAATTTGGACAAAAAATATTTAAAGTTGCATTGGATGGCGGGTTTGACTGTCCTAACCGCGATGGCACTGTAGCACATGGTGGATGTACATTTTGTTCTGCTGCAGGTAGCGGGGACTTTGCAGGTAATCGTGCAGATTCAATCGCAGTACAATTTAAAGAAATTAAGGAAAAGATGCATGAGAAATGGCACGAAGGAAAATATATTGCTTATTTTCAGGCATTTACAAATACACATGCACCAGTTGAAGTATTAAAAGAAAAATTCGAACCTGTACTTAAAGAACCGGGTGTTGTAGGATTATCTATTGGTACGCGTCCTGACTGTCTACCAGACGATGTTGTCGAATATTTAGCAGATTTGAATCAACGAACATACTTATGGGTTGAATTAGGACTACAAACAATCCATCAGTCAACATCTGATTTAATCAATCGTGCCCATGATATGAAAACTTATTATGATGGTGTGGCAAAATTACGTAAGCATAATATCAATGTATGTACACACATCATTAATGGCTTACCTGGCGAAGACTATGACATGATGATGGCTACTGCCAAAGAAGTTGCACAAATGGATGTACAAGGTATTAAAATTCATTTACTTCATTTGTTAAAAGGTACACCGATGGTAAAACAATACGATAAAGGTTTATTAACTTTTATGACTCAAGAAGAGTACACAAACCTAGTTGTGGACCAATTAGAAGTGATTCCCCCTGAAATGATCGTTCACCGAATTACCGGTGATGGTCCAATAGATATCATGGTAGGTCCAATGTGGAGTGTTAATAAATGGGAAGTATTAAATGGCATCGATGCTGAATTAGCACGTAGAAATTCTTATCAAGGCTTGCGTTACAAGTCTAAGGTGAAGCAATGAAATTAGAACGTATACTCCCTTTTTCAAAAACACTTATTAAACAACATATAACACCAGAAAGTATTGTTGTGGACGCAACTTGCGGTAACGGCAATGACACTTTATTTTTAGCCGAACAAGTACCAGAAGGACATGTTTATGGTTTCGACATTCAAGATTTAGCTTTGGAAAATACACGTGATAAAGTTAAGGATTTCAATCATGTTTCTTTAATAAAAGATGGACATGAAAATATTGAACATCATATAAATGATGCACATAAAGGTCATATTGATGCAGCCATCTTTAACCTAGGTTATTTGCCTAAAGGTGATAAATCTATCGTGACAAAGCCTGACACGACAATCCAAGCTATTAATTCATTGCTATCATTAATGTCAATTGAAGGTATTATTGTACTTGTTATATATCATGGTCATAGCGAAGGACAAATTGAGAAGCATGCATTGCTTGATTACTTGAGTACTTTGGATCAAAAGCATGCGCAAGTTTTGCAATATCAATTTTTAAACCAACGTAATCATGCTCCATTCATTTGTGCCATAGAAAAAATTTCTTAAGCATTTGCTGCGCTATACTATTTATAATTTAGGATTGAGTAGTCAACATTTGAAAAATTAATACCAACAACAACAAAAAGAGGTTTTCAACTTAATGAAAACCTCTTTTTATGCTATTAAACTTACACAGCAATAATTGCGTTTAAACTATTTTGCATTGCTGTTGCTCTACTTGCAATGGCATCACTGATGAAATTCAACAACTCTACTTTCTCTTGTTGTAACTTTTCATTGAAATGAATAATAACTGTTCTTTCATCGTCAACAGGACGCTCTTTGTAAATCCATTCTAATTCAACTAAATTATTATACGTTCTCGTACGCTTATACGGTTTAACTTCAACAAATCTGTCCATTTCTTTAAGCGTCATAGAACCTTTTTGCCATAAAGTTAGTAAAATTAAAATTTCTTCTCTAGACATTTTGTATTCGCTTTCAATCTCGCTGAAAATTGAGTTAATGTCACCCAAAAGTGTTTCTAATTGCAAAATCCCAAATACAGTGTCGTTATTTACTTTTTTCATGCTAAACATCTCCCAATTAATAATCACATATTTAGCTACCATACAAGTATTAACAAACATCCCAACAATCCCAAAACTTGTATGTGCTAACTTATGCATAAAACTACAAGTGTAAATAAACTTGCTTTCTATTCAATTGTCAAAGTTGAATAAAATTAAATAAGTATAAAAACCAATAATCAATAGAGTTAATATTTAGAAATAAGATAATAGTACATAAAACAAATCACTCTATTACATATTAATTTTATAATTTATATACAAAGAAAATATATCAATATTACCATTAAATTGCAACAATTCTACATATATTTCTTCAAAAAAGATACGCATTGAATTTTTATTACATATAACTCTCATGAAAATTGATTAAACTAAATTAATTAGTTAGCCTTAAATTTAACAAATTAAATCAAACCGAATGAGGCTAAATTGGTTATTTTTCAAGATATGATTTGTATAAATCAAAACATTTCTTACAAATCAAATGTGTATAAAATGTGATATACATTCTCAACCTTAAAAAAGTAAAAAAAAGATGAGCATCTACTGTCTCATCTTTTTAGAATATTAAATTTCTACAATTTCGTCATCTTCAACAATAAAGCCCATTGTATTGACGCTGTTATTTAAGAAAGTCAGAATATAACGCATTACTTCATCACGTTCTGGCTCATTGTGAACCTCGTGGTAAAAACCTTGCCAAGCTTTAAAATATAATTCAGGTGTTTGATATTTTTCTTTAAACTCATCAATTGCCCTAGTATCAACAATTAAATCCTTCGTTCCATACATTAATAGCGTTGGCATTGGTTGAATGTCATGAATATGAGCCATCGTATCTTTCATCGTCTCATTAATTGTATTATACCAATGATACGTTGCTTTTTTTAACATTAAACCATCGTTAACTGTTTCTTCAACAATTTCTAAATTACGTGTTAAATCTTTTGGTTCTACACCAACATTAAAACGTGTGTCTTTTGAAATTTTACCTATATTTGAAACAAGTTTATCTTTACGATTTTTTCCATTCTTTTGAAGTTCTAGCATAGGAGAAATTAACATCATCCCCTCGATTGGCAATTCTACTTTTTCAAGTAAATTTAATAAAATCAAACCGCCAAGTCCTACCCCTAATACATAAGTAGGAATTTTATATTCATTAGCTATCTTTAACCAATCTAGCAAACTTTCGTGATACGTTTGAAAGTTTTCAATTTGTCCTTTATTAGCTCTTGAAGTTTGACCTTGACCAGGCAAATCTCCCATAATCACATGATAGCCATTTCTTCTTAACATCGTAATAACATATGCATATCTTCCCGTATGTTCTAATATATTATGAGCAATAACAACGACGCCTTTCGCATCATTTTCAGCTTCCCACTTCCACATTATTATACTGCCCCTTTTTCATTAATCTTCAATAACATAATTATAGCAAATTCACTATGTAGATTTCTATTTATAGTATTATTGTTGTCCATATTATTATATATAAATGAAATCAACATCAATAATAGTGTAATTATACATAATTATTTTTGATTGTTTTTTATGAAAACGCTTTCTCGAATATTTTTTTCATGCTAAACTTATTGTAAACACAAGGGTTTGGAGGAGTAGCAATGGCACTATTAAAGAATTTTTTTATCGGATTATCTAATAATAGTTTTTTAAACAACGCAGCAAAAAAAGTGGGCCCACGTTTGGGCGCCAATAAAGTCGTTGCCGGAAATACAATTCCAGAGTTAATTAATACAATCGAATACTTAAATGACAAGAATATCGCTGTTACGGTAGACAATTTAGGGGAATTTGTCGGTACAGTTGAAGAAAGTAATCATGCTAAAGAACAAATTTTAACAATTATGGACGCGCTTCATCAACATGGCGTAAAGGCACATATGTCTGTTAAATTGAGTCAGTTAGGTGCAGAATTCGACTTAGAATTAGCTTACCAAAATTTAAGAGAAATTTTACTTAAAGCAAATACTTACAACAATATGCATATAAATATTGATACTGAAAAATATGCTAGCCTGCAACAAATTGTTCAAGTTTTAGATCGCTTAAAAGGCGAATTTAGAAATGTTGGTACTGTAATTCAAGCATATTTATACGATAGCCACAAATTAGTTGATAAGTACCAAGATTTACGATTACGTTTGGTTAAAGGTGCATATAAAGAAAACGAATCAATTGCATTTCAATCTAAGGAAGACGTAGATGCAAATTACATCAAAATAATTGAACAACGTTTGTTAAACGCACGCAATTTCACTTCAATTGCAACACATGACCATCGCATCATTAATCATGTAAAACAATTTATGAAAGAAAATCACATTGAAAAAGATCGTATGGAATTCCAAATGCTCTATGGTTTTAGATCAGAGTTAGCAGAAGAAATCGCAAATGAAGGCTATAATTTCACTATTTATGTACCTTATGGCGATGATTGGTTTGCGTATTTTATGAGAAGATTAGCAGAACGCCCACAAAACCTATCTCTTGCTGTAAAAGAATTTGTGAAACCTGCTGGCTTAAAACGTGTTGGCATAATTGCAGCTTTAGGAGCTACAGTTATGTTAGGTTTAAGTACAATTAAAAAATTATGCCGTAAATAGAGCATGGCATAAACAATAATTTAGGAGTCTGGAACAATAATCAATGTTCTAGGCTCCTAAATGTTATATTGGCAGTTCTGAAACATTTATAAATCTTTGATTATGAACTCACAACAGCGCTCTATGCTTTTATAGATTTTAATAAATTAGCCATTTCAATTGCACTTACTGCTGCTTCGGCACCTTTATTACCAGCTTTCGTACCTGCTCTTTCCACAGCTTGTTCAATACTTTCAGTCGTTAAAATACCAAATATGACTGGTACATTAGTTTGATCATTTACTTTAGAAACACCTTTCGCGACTTCATTACAAACATAATCATAATGAGACGTAGCACCGCGAATTACGCATCCTAATGTAATTATTGCATCATAATTTCCTGATGAGGCTAATTTTTTAGCTACTAAAGGAATTTCAAACGCACCAGGAACAAATGCTACATCAATATTGTCTTCATTAACATCATGTCGAATCAAAGTATCTTTTGCACCTTCAAGTAATCTTCCAGTGATAAAATCATTAAATCGACTAACTACGATTGCAACTTTCAAATCTTTTCCAATTAATTTACCTTCAAAATTCATGTTAAAGTCCTCCTATATTAAATGACCCATTTTTATTTTTTTCGTTACCATATAATCATGATTATGTACCGTTTCTGGTACGATAACTTCAATTCTTTCTGCAATATCAATGCCATATTGTTTTAATCCCTCAAATTTACTTGGATTATTACTTAATAAATTGATATGTTCGATGTTAAAATATTTTAAAATCTGTGCAGCAATATGATAATCTCGTAAATCTTCATCAAAACCTAATGCTAAATTTGCAGTTACTGTATCATATCCTTGCTCAATTAATTCATATGCGCGTAATTTGTTTAACAATCCTATGCCACGACCTTCTTGAGGTAGATAAATAATCATGCCACCATGTTCATTGATATACTTCATAGACGATTCAAGTTGAGCACCACAATCACAACGTTGACTATGGAAAATATCGCCTGTAAGGCACGCAGAATGTAAGCGTACATTTTCATGTTGTCGAATTGCACCTTTTGTCAGTACAACTATCTCTTCATCTGTGTATGTCGCTTTAAAACCATACATATCAAATGTTCCGAAATCTGTAGGCATTTTCACTTTTGCCTTAAATTCAATTTCTGGTTCTAATTTTTTACGATATTCAATTAAATCATCAATCGTAATCATCTTTAATTGATGTTTTTCTTTAAAATTTTGTAAATCTTGTCCTTTCGCCATCGTGCCGTCATCATTCATAATCTCACAAATGACACCAGCGGGCTTGGCACCAGTAAGTTTAGCTAAATCAACAGCCGCTTCTGTGTGTCCATTTCTAGCTAATACGCCTTTATCTTGTGCTACTAATGGAAATAAATGACCAGGACGATTAAAATCTTTAGCTTCACTACTAGGATCAATGAGCTTTTTGGCAGTCAATGTACGTTCATAAGCACTAATTCCTGTTGTTGTATCTACATGATCAATACTCACTGTAAATTGCGTACCAAAGATGTCGGAGTTATCATCAACCATTTGTACCAAATCCAAACGTTGTGCAATATCTTTAGACACTGGTGCGCATATTAATCCCCTTGCTTCTTTCGCCATAAAATTAATGGTATTATCGTTCATCCATTCAGTAACCGCTACTAAATCACCTTCATTTTCACGATTCTCATCATCTACTACAATAATTGTTTCTCCATTTTTTAAAGCCATTAAAGCACTGTCAATATTATCGAATTGCATGCTACCCCTCCTAAAAACCAAATGCTCTTAATTTATCTACAGATAATTGGTCTTTATCTTTATTTAAAATATTTTCAACATATTTAAACAAAACGTCTGTTTCTAAATGTACTTTATCTCCTAATTTTTTGGATGATAAAATCGTTGAACGCCTCGTTTCTGGAATAAGATGAATGTCAAAACTGTTATCATGCTTATCAAATACCGTTAGACTTACACCATCCACAGTAATAGACCCTTGCTTAACTAACTGATTATTAATATGTTGGCTACATTGAATCGTAATAATTTTGGCATTGGCTGTTTCATTTATTTTTGAAACTGTTCCTAGTTCATCTACATGACCGAGGACAAAATGTCCACCAAACCTACCGTTACCACTCATGGCACGCTCTAAATTTACTTCTGATTGTCGCTTAACATCTGCTAAATAGGTTTTATTTTCAGTGCTTTTAATTACTTGAACAGTAAAAGATGTCTGATCAAAATCAATCACTGTTAAACATGCACCATTAACACTGATGGAATCACCAATATGCATATCTGCCGTAATCTTATGTGCTTCGATTTCAATCGTCCTGACTGATTGACGAATTTGAACACTTTTAACGACACCTATTTCTTCAACGATGCCAGTAAACATGCATCATCACTTCTTTCGTAAAGTTAATTTAACATTTTGATTTAATAACTCGGAATGAACAATTTCAAATTGGTTCGCATCTGGTATCTCAATCACATCATTTGTTTGATAAAATTGATAATTTCCAGATCCGCCAATTAATTTCGGGGCATAATAGAGAATAAATTCATCTATATAATTAGATTGGAGAAATTCTGAAGTAGTGGTTGGACCTGCCTCGACTAGCAAAGTTCCAACTCCTCTTTTATATAAATTGTGAAGAATTGTTGTTAAATCACAAGACTTCAAGTAAATAATTTCAATATGTGTTTGATTGCTTGTTAAATTTGGATTTTCAGTATATATCCAAATTGGTGTTGATTCATCTTGATAAATTTGCTGATTAAAATGAATATTCCCAGACTTAGACAATATTACTTTTATAGGGTTTTTTCCATCTTGAATACGTGTAGTATATTGTGGATCATCTAATTCAACTGTACGTCTTCCAGTTAACACTGCGTCGTGTCGATGTCTTAACTTATAGACATCTTGTTTAACCTCTTTGTTAGTAATCCATTGACTTTGTCCATTATCATTCGCTTGTTTACCATCTAAACTTGCAGATACTTTCACTGTAATTTGTGGCAGTTGCTTTGCTTTTGCTTTAAAAAAGTCTTGGTATAATTGTGATGCCCGTTCATCATCAACGCATTCAACCTCAATACCGTGAGCCCGTAACGTCTCATCACCATGTGTGTCTAACGAATTGTCTTTTGTTGCGTATACTACTTTTGCTATCTTACAATCAATAATTTTGTTAACACAGGGTGGTGTTGAACCAAAATGACTACATGGCTCTAACGTAATATAAATCGTCGCACCTTCAGCATTTTGTTGTGCCATATCAAGTGCTTGAACCTCCGCATGCTTGTCACCTTTTCTCAAGTGTGCACCAATACCAACAATCCTACCTTCATTAACTACAACAGCGCCAACGGGTGGATTAACACCTGTTTGACCTTGTACCATATTTGCAAGTTGAATCGCATAATCCATAAATTGACTCAAATGATCACCTCTATAAACAAAAATCCTCACATCATGAATTAAGATGCAAGGAGAAAAATTTATCGTTAAATAAGCCTATTTGTACACATTTTTACAAATACGCTACATTATCTTTGTCGATAATTAACATTCTTTCTCCCATCCAGACTTTAACTGTCGGCTCTAGAATCTCACTAGATCAGCCACTAATATGAAACATATTAGCAGGTCGCAGGCTTTATTTACTGCCGGTTGGGAATTTCACCCTGCCCCGAAAGAATTATATATGAAATTGTTATAGATTATTTGAGTACGTAGTATGTCAACTACATTTAAAATGATACTATATGTTTTCTGAAAAAACAATTAATGACGGTTTTAATTTAATATAATCTGAGTACTATAGGCATCTCATTGATATGATTCTTACTAACAGACATTAAAATCAAACCTTCAATTCGTCTCTATAGAGCGTTCTCTTTATTATCTTCTAGTTACAAATTATTGATTGTAACTGCGCTGTTGTTGCTCATTCGATTCTAAAGCATCATATAATTGAGATACTGTATGCGCAACTTGTTCTACTATCATTTTCACACCATTTCGTAGTTTATTAACACCGTTTGTCATTTGACCTATCGCAATCATATTTGTTAATGTTCCAAACCTTGGACTAATAACTTGATTGGTTTCCGGTATGATTTGTATGCCTCCCATTGGATGTGCTTGTACAATTTGTCTATTTTCAAGATTTTTAATTAATTGATCATCTTGATCCAATTCATTTAAATGACTTTTTGCACCTGTCGCGTTAATGACAACATTATACATGTCTACTGATTCTTGGTTTTTGTATGAAAAATAATACAACTTGCCATCATGTTTCACATCTTCTAAATCTTTTTTCAAAATTAAAGACTTATTTTCTATTAATTCAATAATTAGTTCAGCAGTTCTTGGAGGCATTGGATTTGAATTTAATTGAATCATCTTTGAGTATTTTTGATTAAATTGATGTTGATCTTCAATACTTAAGCTATTCCATATCCAATTTAAATTCTCTTTCAAATGTTCAATCATACTTTGGAAAATGCCCATTTCTGTTGGACGCGCTAAATCATACTTCAAATCTGCAATATGATTTCCTGTACGTCTATGTACTAATTTTTTAAAATCAATGTCATATTCAGCACATTCTTTTAAAAATAAAGAAACTATAGTATCAAGCGGTGCATTGCCGAAATGATGTTTTTTAATGTCATTTAATTTGTCTTTAGTTAAGTACTTGAATGTCACGTCTATCATTGTACCTCTTACACTTGGTAAATGAGCAGAACGACTCGTCATAGTAATTGGTAATTTCGGATGATGAGCAGCAACATAACGGACAACATCTAAACTGGCAAGGCCTGTACCAATAATCGCAATATCGTCCAGTTCATTTACTTCGTCTAACGTATTATATGTTGGATAAGGCGTAGCGATATATCCTTTTTTACCCTTTAAGTTATATGGATCATGGTAGGCAAATGTACCACATGTTAAAAATACATAATCGTACGCTTGCCATGATTGTTCTGAATTTGTAGTACATATGTAATAAGTTAAATTCGTTTCATCGATATTAGAATTTGTATAAATCTCTTGAACTTTATTATAATTAGTTGATATATTTGGATATTTTTTCGTGAACATAGATAAATAAGATTTCATATAATGTCCGAATACAAATCTCGGTAAATATGCAGGTTCATCAAAATTAAAATCAGTTTGTTGTTTATACCACTTCCAAAATTCAGTCTCATCATCTAAATTTAAACTCATCTTTTTCGAAGGCATATTAATTAGCAGCTCAGAACTATCATTTTGAAATGGTACGCCCTGTCCCATATTTACTTTATCATCGTATAAATCTATATCTAATTGATTAAACTTCGGGTGCTTAACTAACTCTCTCAATACACTTACACCAGCAGTTCCCATGCCTATTATTGCTACACGCATATATCATCCATCCTTTTGTAATTCAAAATATTATATTTAAACTATTACCTATAATTATAGCAATTTGGTATTTCCAATAAAATTTATTAAGGTAAGCTATTATTTCACTTTCACAACCATTAAACCATTTAAAACTTTTCATTTAATATCAACCTTAGTGTTTGTGTTAAAATATTTTTAACGAGGTGAATTAAATTGAAATTTATAGCAAAGATATTAATCTCATTAGTAATTCTATTTATGATTTTTAGTCGTAAAAACAAAGCTTCTTAATCAATACCCTTGATTACAAAATAAATTCAACTAAGGTGATTGGCCATACACTCAAGATATGGCTAATCACCTTTTTCAATGCAAAACAAAGAGTATATTTTGCAAAATCAATATCTATAATTTATCTTTAATACCCTTTTAATACTAAAACCAAATTCAAATTACATAGTCATATCGTGTAATATACCAAAGGAATATAGACATTCATCTATATAGATGATAATCTATTTAACGTCTAGGAGGTATGTTATGACGTATAAAGAACTAGCAACATTTTTAAAAGTTTTATCAGATTCAAGCAGATTAGAAATACTAGATTTACTTTCTTGTGGAGAGTTATGCGCTTGTGATTTGTTAGCACATTTTCAATTCTCTCAACCCACACTTAGCTATCATTTGAAAGCATTAGTAAAAACCAACTTAGTTACGACACGAAAAATCGGAAATAAACATTTATACCAGCTTAATCATAATATTTTTGAGTCCGTAATTAATAACTTGTCTAAGGTTCATACCTCTAACCAACGATGTTTTTGTCATAACCTTAAGACTGGTGAATGCTAATGATGACAACTTTAGCGACACTCATTTTTCTAGTAACTTTATTATTTGTATTATGGCAACCTAAAGGCCTAGATATTGGCATTACCGCATTAACTGGTGCCTTTATTGCTGTTATTACTGGTGTTGTAAGTTTTTCCGATGTTTTCGAAGTAACAGGTATTGTTTGGAATGCTACTTTGACTTTTGTCTCAGTCATTCTTATTTCATTAATATTAGATAAAGTTGGATTATTCGAATGGTCAGCTATTCACATGCTTCATGCTTCAAAAGGAAATGGTTTAAAAATGTTCGTTTATATCATATTATTGGGTGCCATTGTTGCTGCATTTTTCGCAAATGATGGCGCAGCGTTAATCTTAACGCCTATTGTATTAGCGATGGTTAAAAATATAGGTTTTAGTAAGCGGGCCATATTCCCTTTTATTATTGCGAGTGGTTTTATAGCTGACACAACTTCTTTACCTTTGATCGTGAGCAATCTAGTGAATATTATATCTGCTGATTATTTTCATGTAGGATTCGTTCGATATTTTAGTAGAATGATTATACCTAATTTATTCTCGCTTTTAGCAAGTATTATAGTATTGTGGTTATATTTTAGAAAGGCGATACCTAAAACGTTTGATGATAATAATATAAAGCATCCTAAAGATGCCATTAATGATTTAAAGCTATTTAAAATTTCATGGATTGTTCTAGTTATATTACTTTTCGGCTATCTAATCAGTGAATTTACTAAAATTCCGGTATCAATTTTCACTGGAATCATTGCTTTTATTTTTCTAATGTTGGCTCGTAAATCAAATGCTGTAAATATTAAGCAAGTCATTAAGGGCGCACCTTGGAATATAGTATTATTTTCAATTGGTATGTATATCGTCGTATTCGGCTTAAGAAATGCTGGCATTACTTTAATATTGGCTAAAATATTAGAATATATTTCCAATTACGGTCTATTTAGCACCATTTTGGGAATGGGCTTCATTTCAGCGTTTTTATCATCAATAATGAATAATATGCCTACAGTTTTAATAGATGCGATTGCTATTGGTCAATCAAATGTCCATGGCATGTTAAAAGAAGGCCTAATTTATGCGAATGTTATCGGTTCTGATTTAGGTCCAAAAATTACACCGATAGGCTCTTTAGCTACATTACTGTGGTTACACGTCTTAACACAAAAAGATGTTAAGATTTCTTGGGGCACATACTTTAAAACTGGTATCATCATTACAATTCCAGTACTATTTATAACCCTCATAGGGTTGTATCTAACACTTATCATATTTTAAGAAATAAAAAGACGCTTTCTATTTATTGCGATAGAAAGCGTCTTTTTATACTTGAGCAAGTTATATCATAACTTAACTCTATCAAATTACTTATTCAAATGTTTACTGTCATCTTTATACACAAAGTATTTGAAGTATTTTCCTTCAGTCTTCATATTCTTATAAAAGTCAGCGATAATTGTTGCATTACTTTCTGCCCACTTAATATCAGTAGCATATTGATGTTCTCCTGGATTTTTTGGATTCCATCTCATACTATACAATGTATTTTGATCTGTGCTTGATAAGAAGTGCTTATGAATGAAATCAGCACCGCCTGAAATAGCTTTTTCAGGTGTATCCCAACCATGCTTTTTAGCATATTCTGCACCTGTTTTAATTGGGTCTTTATCAAGGGCTCCTACTCCATAGAAATTGTAGTATTTTTTGCCATCAATTTCGACTCCATTAGCTAATTCACTTTTAACTGCGCCAGTTTCTAATAATGCATGTGAAATTAAATAAACTTCGTTAACGTGCTTATCTTTAGCAGCTTTTAAGAAATCATCCGTATGTTTCAATAACGTTGGTCTATCTACTAACATACGTTTAATTCTATTTTTATCAATCCCTTGATACTTTGATAAATCTAAAAATTGATATTTTTGCTTTTCATTATCGATAAAAGTACCGCTATCCATTGCACTTTTAATTTCAGTTGCAGATGCATCTCTCCATGCATCATTCTTTTTATTTGATACCTGTTGACTCGTATAATTATTTATTTGTTTCTTTGCTGCATCGTTTAATGTAACATTTAACTTTTCAATCTTAATGTCGGATTTAACATGTTTGAAAAATATCTGATCGGATATCATTGAGAAAAATAAAAATGAGACAACAGCAAATATGACAACAAGTCCTATTATTCCAAAAATAGAACCTTTCTTGTGTTTATTCATATCCACACCTCTTAGGTCATTGTTGTTATACATTCAGTTTGACTACGATAATAAAGTTTAACATTATTAAAACCGTTTAACAATTTTATCTATGCATTGTTACATATTCATAAATAAACAGTAATGTAAATGAAACGTTTTAAACCATTTATCAACATTACTTTACGTTGATCTACGAATCATAAATGTTTTATCTTTTTGTATAACCTTTGAAAACCTTTATATCAATAATCTTATTATTCACGTATTAAAAAACAAAAAATTCTTTTGTTCGTTTACTTAGTTTCTTTTTTATAATCCATCATAATAAAACTTGCTGCATTTGATCTATTTTTATAATAGTACTGATTTAAATCAATCGTGCCTTCAATTTGACCATCACGATACATCATTTCATTAGTGAAGTTATTTATCATCACGAAATCAGCGCGATCTCTTATAACATCTAAATCGTCGTTTCGTGCAAAAAAATGTTCTAAATTTAAATGTGCGTAATCCATTGTTACCTCCCGATTACAAATTTTGTTCTATCTACTATTTAGCAAAGTAATAATACATCATATCACATTAAATTAATTACTTATGTCTTATATTTAACACTTAATTTAGCGATTACGCAAATGAATGATTTTTCTAAATATTTTATTCTAACTTTATCCGGAAATATTTGTTATACGTATAACTTGGAGAATGACTACTTGAAATTTAATGACGTATACAACAAACACCACAAAATCATACACCATCTTTTAAAAAAATATAATATTAGCTATAATTATGATGAGTATTATCAACTACTCTTGATAAAAATGTGGCAATTGAGTCAGATATATAAACCCTCAAGCAAGCAATCTTTATCCTCTTTTTTATTCACTCGATTAAATTATTACCTTATCGATTTATTCAGACAACAAAATCAATTAAAAGATGTCATTTTATGTGAGAATAATTCACCAACATTAACTGAACAACCAACATACTTTAATGAACATGACCTTCGTTTACAAGATATCTTCAAGCTTTTAAATCATAGAGAAAGACTATGGCTCAAACTATACCTTGAAGGATACAAGCAATTTGAAATTGCTGAAATCATGTCATTATCGCTTTCAACGATTAAATTAATTAAGATGTCCGTTAAGCGTAAATGCCAACATAATTTTAATTAGTTTATTGTGAAATTTCGGTCGATGTGTTAGTGATGTTGAAACACCCTAACATCTTCATATAAATTTATTTTAACCATTAAATTAACAACTTATTATACGAGGAGTACTATATTTGCAAGACAATTCTACTAAATATCTACTTTATATCCAAACTGCTACTTCAAACCATCTCGAAACAAATTGTGTCTTTTTACATTGCGATTACATTCTTAAAGTTCCAATTAACAAACTCGTTTCATATTATGCGAAATTGCATTTATCATCACAAAGTGTGCTAATTGAGACTGCAAAAAACATACTAAATATTAATAAACTGGTTCCTATTTACATCAACCCAAAAACTATACTTTTTCCGTTAAAACATAAACGTGCACCGATACAAATTTATATCAATGCACATTATATTGTTGGTATGACTGCCATAGAGAATTCAACATTAATACATTTTCAAGAAGGCATTCAGCTAGAAGTTGATGAGCCATTTTCTCTAGTTTCAAAAAAATGTCATGAAAGTTTAGCTTTGAAGCACTTCATTGAAAATACTATTTCGAATTAAATTTAATTTCTAAAAGTTTCTTAGTAAAGTATGATGTCACAATTTTTATAAAATATATGCTAACAATCATTAATAAAATCGCTCCAATAATTGTTAAAATAACAACAGTTGTTGATAAATCTACCTTAGGACTAACGAAAAATTGTACGCCAGATAGACTTGTAATTAGCCCAAATAAAAACAAGCCTAATAAAGCAACATAAGCAAACATCATCACTACTAATGTAACAAACATACTATAACTTTTTGTTTCTTTATTTCGAAATACATTTTGTCTTAAGTAAGCATTAGCAAAGGTAACAGGCTTATTTAAGTTAACGCTGTCATCATCAGATATAGAAGATAATCGTTGATCTAATGCTTGTTTCTCCTTCTTGTTCAAAAACCATAATTGCTTTTTAACTTTTTTATCAAATGATGCTTTATTCATAATTAAGGATTTCTCTCCTTTATAATATTGACGTAATTTTAAACATTAGCGTCAATTGAAAGTGTATTTTATATATTTTACAGAAATATATGTATCAAATCTACAAAAATCCATATTACAATTTCATTTATGGTGATTTGACGCTAAAATACAGTCTGCTAATTTTTCAAACTAATGCTTTTTAGGTAGGTACAATGATAAATTTTAATCGTATATATGTTTCATATATAATGAATCTAGCCTTAACCATATTGCATTCAAAATAATTTTAAAAAATGAAAAGAAAGGATTTAGCATGCAAAAATTCAAAGACTTTTTTTACGATGATTTATCGGTTACACGAGGAAATTATTTTTTAACTTTAATGGCAGCATTTTTTATTACTATCATTTTATTTATCGGCATAGTTGTCAGTGAAGTACATTTACTTTATAGCATGCTAATTGTATTAGTAGGTTTAATTCTATTGAGGCTATTCAAAATCAATTTATTCTCTTTTAAAAAATTAACATTGTCTCAAGTTATTTATATTATAGGCGGTGCACTATTAATTTATGGGTTAGATAATCTTTATTTATATTTTCATGACGTACCGGCAAATGAACTACAATTAGAGCAAGAAATACGAAATACACCATTCTATATTTCTATTTTCACTGTTACCATCATCCCCGCTATTGTGGAAGAAATTGTTTTTCGCGGTATGATAATAAGGGTTATATTCAGAAAACACTTATTTTTAGGGTTACTTGTGTCTAGTTTAGTTTTTGCATCATTACACGAATCTGACACTTGGATTGGTTATTTACCTTACTTATATTCTGGTTTGATTTTTGGTCTAATTTATATAAAAACAAAACGATTAGAAGTGGTAATATTCATGCACTTCTTAAATAACTTGTTAGCTCTGCTCTTTATAATATGGGGATAATTTTGAGATAACCTTTCATATTATTTTCAAATTATCTATCTGATATTTATTTTATTGAACTTGAGTCACCACTTAAACTCAAAAATACGTGTCATCAAGTGCAAAATAATTTAGAACTAATACAAACATAAAAACTTTTGCTTTACGCTTAAAATCAAAAGTCACATACCTAGATATAAGTACAACTTGTATATTTTGTACTCTAATAAGTATGTGGCTTAAATAATATTTAATTCTTGAGTTGCATATAGTAATTGTTTTTATTCATTTTCTAAAATATGCGAGACTAATTTCCTTTTCTACTCCTGTTGAATCAATTTAGACTTTTTTATAACTCGGGCTTTTACTTAGCTGAATTTTGACTTCTTCTTCATTAATAACTATGATGGAAAAACCCCCATAAGCACAATGCCTATGAGGGTTTAAATATGTTTATAAATTATAGAATAGAAAGACCTGAAGATTGAATATCTTTCGCAAAGCCTTTAACTGTATCTACTGATAATTCGTTAATATCGCGACCTAAGTTTGTATTCACTTTTTTCACAACATCTGCAGGGCGTGTAATAATATCTGCACCAATTTCATCAGCTTGAATCACATTGAATAATTCGCGGCAACTTGCCCATAATAATTTAACGCCGTCTTTACTATGCGTAACTTTTACAGCCTCTTTCATTAATGGTAATGGATCTACGCCTGTATCTGCAATACGTCCTGCAAATACTGAAACATATGTTGGCACACCTTCAGTTACTGCTTCAGTTATTTCTTTAACTTGTTCAATTGTGTAAACAGCCGTAACGTTTAATCTCACATTGTCAGCTGAAAGTTTTTTAATTAAAGGAATCGTTGATTCACCTTTTGTATTTACAATAGGAATTTTAACAAATACATTTTCGCCATATTGTTTTAAAATTGCTGCTTCTTTTTCCATAGTTTCTAAATCGTCTGCAAATACTTCAAATGAAATTGAAGCATCTGGAATTTCTTTCACAGCTTCTTCAGCAAAAGCTTTGTAATCTGTTACGCCCGCTTTCGCCATTAAACTAGGATTTGTTGTAAAACCATCCACTTGTTTGTTTTTATAAGCTGCTTTCATTTCTTCAATATCTGCACCGTCCGCAAATACTTCTACATTTAGTTTAGCCATATAATATAGCCTCCTTGATTCTTATTAAAATTTTAACAACATCTGCATGTCTTTTTCTTACAACCATTTGTAAAAAATGATTTTTATTTCTTTGTTATATAAAACATTTATATCACGCTTTTATAATATATAGCTAATTTTTTGCCTATATTTTTTAAAAATGACTTTAGCAAACATTGTGTCTACAAGTTAATAAAACTATTGTTTTATGATTGTTTATGATACGATATGTAAATGATAATCATCCAGGAGGTCTAGCATGTCTCGTTCAAAAAAATACTTTTACTTATCTAGCTTAATGATTATTTTAAGCTTTTTCTTTAATACAAATAACGTTTTCCTAAGTGGATTTTTTAATTCTTTTATTAAATTAATACTTTTCTGCAGTGTTATTAACTCAATTGTACTAATTTTGTCTATAATTTTTGCAGATCGTTCAATTAAATCACTAAAGCCTGATGCAGATTGGATTAGAATTGCGAGTAAAAGTTTGCCTTGGATTATTCTAATTGTTATTTTAGTACATATCTTTTCAATTGTTCGTACATTCGGTTTTATTTAAAAAAGATAAAATGTCAATGTAGCGTTAATACAAAACAATACAATGTATCATGCTATAATGAGTAAAACAATTTGATGACGTTGTTGCGTATAAAAAATATTAGATTTTCGAAATCATAACTATGCATCTAATCGCTATAGTTATACAACAAGATATAACATATAATGAGGTTTGATAATGCATCGACAATTTTTGTCGTCGTGTTGCCAAAACCTCTTTTTTAAATTCAAACTACTTCTTTTCGAGGTGAACCAAATGCAATATGTATATATTTTTATCGGTGGTGCTTTAGGCGCTTTATTACGTTACCTCATTTCTTTTCTGAATACTGACGGAGGTTTTCCAATCGGAACACTGATAGCCAATTTGACTGGTGCCTTTGTAATGGGATTGCTAACAGCCTTAACAATTGCATTTTTTTCAAACCATCCGACCCTAAAAAAAGCTATTACGACTGGTTTTCTTGGTGCTTTAACGACTTTTTCAACATTTCAATTAGAATTAATACATATGTTTGATCATCAACAATTTATAACTTTACTACTATATGCTGTAACAAGTTATGTCTTTGGTATTTTGTTATGTTACGTCGGTATAAAACTAGGTGGTGGTTTATCATGATATCAATCATTTTAGTCATGATTGGCGGCGGTTTTGGCGCAATTGCTAGAAGTGCCATTACTGATTATTTTAATCATAAATTTACTTCAAAGTTACCTATCGCAACATTGATAGTAAATCTAGTTGGTAGTTTTTTAATTGGATTAACTATAGGCCTATCAATTTCAATCTCATGGTTCCCTGCGTTCTTTGTCACCGGTTTTTTAGGTGGCTTAACAACTTTCTCAACGTTAGCCAAGGAACTTACATTAATGATGACACCAAAATTTGATATTAACCTTTTTCTCAATTATTCACTTTTACAATTCATCATTGGATTTATAGCTTGTTATATTGGCTATCATATTTAAAAATAAAATGCTTCATTCAGCAAATAGGTAAATTACGACACCTTCCTGAACGAAGCATTTTTTAATTTTCATGCAAATTTTTTAACACCATATAATGCCTATCAAAATAAAACAATCTTTGTTGCCGTTTAAATAATGTGAATGTCAATAAATTCTCCAAACTAGTCGAAAATAAAACAGGCTGGGACATAAATCCCTAAAAAAACAGCAGTAAGATAATTTTCAATTAGAAAATATCTTACTGCTGTTCTCTATTTATACAATACTTCGTATTGAATGGCTTCGCTTTCCTAGGGTGCCGTCTCAGCCTCGGTCTTCGACTGGCACTGCTCCCTCAGGAGTCTCGCCATTAATACTACGTATTAACATGTAATTTTACTTTTACATACTTTAAAAAAATAAGACACTTTGCCCAACTTACACTACCAATAGAAACTTCTGTTAGAATTCCTTAAAATGATATTTCGCGATATGTAAATGAAATTGTTGAAACGATACCTGATAGCGAATTCGATGAATTCAGACATCATCGTGGCGCAACATCCTATCATCCAAAAATGATGTTAAAAATCATCTTATATGCATATACTCAATCTGTATTTTCTGGTCGTAGAATAGAGAAATTACTTCATGACAGTATTCGAATGATGTGGTTAGCTCAAGATCAAACACCTTCTTATAAAACTATTAATCGTTTTAGAGTGAATCCTAATACTGATGCGTTAATTGAATCTTTATTTATTCAGTTCCATAGTCAATGTTTAAAGCAAAATCTTATTGATAATAATTCAATTTTTATTGATGGTACATAAGTAGAAGCTAATGCCAATAGATATACATTTGTGTGGAAGAAAAGTATTCAAAATCACGAGAAGAAATAGATTTAATTGGTAGTCATTTAGATAAAGAAATCGAAGATTTAAATCATTCTATTTAGAACGAAGATTGTGCTCAAATTAGAAAACAGACCCGTAAAAAAGAACTGAGATTAAGAAGTTCAAAAAGAAATTTGATGATTATTCCGAAAGAAAAAATAAATATGAAGAACAAAAATCGATTCTTAAAGATAGAAATAGCTTTTCTAAAACTGATCATGATGCAACTTTTATGAGAATGAAGGAAGACCATATGAAAAATGGCCAACTTAAGCCAGGATACAATTTACAAATAGCGACAAATTCTCAATTTTTTTATCCTATGACCTATTTCAAACCCCAACAGATACTAGAACTTTAATTCCATTTTTAACAATGATTCAAAATACCTTCGGTTATTTACCAGAGTATATTGTAGCTGATGCAGGTTATGATAGTGAGCAAAACTATATGGCTATTATAGATGATTTTAATAAAACGCCACTTATTACGTATGGCATGTTTATTAAAGATAAAACTAGAAAGTTTAAAAGTGACATTTTTAACACTCAAAATTGGAAATATGACGAACTTAATGATGAATTTATATGTCCTAATAACAAAAGAATAGGTTTTAAAAGATATGCATACCGTAATGATAGATATGGTTTTAAACGTGACTTCAAGCTATATGAATGCGATGACTGTTCAGCATGTTCTTTGAGGCAACAATGCATGAAACCAAATTCGAAATCCAATAAGAAAATCATGAAGAATTATAATTGGGAATACTTTAAAGCCCAAATTAATCAAAAGCTTTCTGAACCAGAAACGAAAAAAATCTATAGTCAAAGAAAAATTGATGTAGAGCTTGTTTTTGGATTTATGAAGGCTATTTTGGGTTTCACTCGAATGTCAGTTCGAGGAATAAATAATGTTAAACGAGAGCTAGGTTTTGTATTAATGGCACTTAATATAAGGAAAATAGCAGCTCAACGAGCTGTACATTATAAAATACATATCAAAAAAGCTGATTTCTATCAAATAATTAATAGAAATCAACTTTTTTACATTGCCTAAGAACTTAATGTCCCAAGCCCTGACAATTCATCTAACCTTTTCATCAGTTGAGTGATTTTAATCTATCCTTCAAAAGTTTTTGGATCAGGTCCAATTCTCTTATCTTGATTTAAACCATCAATTCGCGTCATTTGTTCATCTGATAATTCGAAATCAAATATTTGGAAGTTTTCAGAGATTCTGTTTGGTGTTACCGATTTAGGGATTATAACCACACCATGCTGCACATTCCATCTTAAAACAACTTGGGCAGGTGACTTTCCTAATTCTTGAGCAATGTCTTTAATTGTCTCATCATTTAAAATTTGTGCATTCATCAATGGTGACCAAGATTCCATCACGATATGTTGTGCTGCCAAATATAATTTCAATTTATGTTGCGTTAAATATGGATGATATTCAACTTGATTAATTACAGGTTTAATTGACACTTGTGCCAACAAAGCTTCCAAATGTTCAGGTTCAAAATTGCTGACACCTATATTTTTAGCTTTATTATTTTTATATAAATCTTCCATACCTTTCCATGTATCAACCATTACGGCTTCGTTCGTGCCTGGCCAATGTACTAGATACAAATCTAAGTATTTTAAACCTAATCTAGATAAACTAGCTTCGTAAGCAGCTGCTACATTTTCACGACCGAAATCCTCAAAATATAATTTTGAAGTAATAAATAAGTCTTCTCTAGCAATACCAGTTGACTCCAATCCGGCACGAATGCCAGCACCTACTTGTTCTTCATTCCCATAAACTTTTGCGGTATCAATACTACGATATCCTTGTTCAATGGCATACTTAACACTTTCCATGCAATTTTCATCATTTTCCACACGAAATGTCCCTAAACCAATTTGTGGCATCGTGTTTCCATTATAAAATGTTTTAACCTCCATAAATATCGCCTCACCTTTTTGATGTATTATACCCTGTTATCATAACAAATCTGAGTTGAATACATGAGAAAAAACACTTAGAGCAATCAACCACTAAAATTCTAGTAATATCTCTCAAACATTAATCAAATTGTAAAAGCAATTATGTTTAATTTATGACAAACTAAAAAAGCCGAAGTCACAACATATAGTCATCACTTCAGCCTAACATTTAATTGAATGATTCAATTTTATCCATCATTTGTTGTAAGTCTTCCACGTTGTATTGAATACGACCATGGAATACAAATTTGTTAAAGAACTCGTCTAATTGTTCAGCACCGACAAGCACTTTGACAGCACTATTTTGATTATAATTTGAAATCGTTACATCGCCTTCATTTTTAGGATTAAAGTATAAAATTGAAGTTGGCGTATATTTGGCACCTAATTCTTTTTGTAAGTCTTCAGCCAATTGTTTAATCGCCTCAATTTGATCTGAATAATTTACAAAAGATAATGAACGTTTGTCATCATTTTGATCCATCACAATAGTTTGTGGTCTAGATTTATCTAAATCCAATGTATCAAATACTTGTTCCATTGGTGGTAAATCTTTAAATTGACCGCCACTAATACCATTATAAACATGACCTTTTAACAATTGAGAATCAATAATATAAAGACCAGTTCTTGTTAATACTAAATGACTAATTCGTTCAATATTATTAAAGCCATCCTTTGGTAAAAAGATATTTGCCATAATGTGCATATCTTCTGGTCGAATTCGTTTTTCTTTAACTAATCTTTCACGAATACCAATTAATCTCATGTCCGTTACATATTCACTATGATTTTTCGAGAACAATTTTAATGCGTCAATCTCACGATCTTTTGTACTAACCATGTGATTATAATCTTCTTGTTGTTTTGTAATTGTCTTTTTATTTTGAATACGCTCTTTCTCTAAAGCTTCTTCATGAGACTTTTTAATGTTTTGTTCTTGTTGTTCATACTTTTCTTCTGTTTGTCGCTTAACTTTTTTCTTACTACCTAAGGCAACTAAGAAAAGGACAAAAAAGATTAATGCAATGACTACTGCAATAATGAGTCCAATGACTACCGGTGAAGATAAATCCATCACAACAACGCTCCTTTTTAATATATGAATAACTTTAATTATAATAGAAAAGCTAAAGATTTTCGATACATATTATCATTTATATACCGAAAATCTTTTATTTAGCTATATTAAATTCATCTTAATATTTTACTGCGTCTTTTAATTCTTCCACTTTGTCTAATTTTTCCCATGGGAATAATACATCTGTACGTCCAAAATGACCATAAGCAGCAGTTTGTTTGTAAATCGGTTGTTTCAAATCAAGCATTTTAATAATGCCTGCAGGTCTTAGGTCAAAGTGTTTTCTAACTGCTTCGACAAGTTGTCCTTCAGAAACTTTACCTGTTCCAAATGTATCAATTGCAATTGACACTGGTTCTGCAACACCAATCGCATATGCCAATTGTACTTCACATTGATCTGCTAAACCTGCTGCAACAATATTTTTAGCCACATAACGTGCAGCATATGCAGCTGAGCGGTCTACTTTTGTAGGATCCTTACCACTGAAGCATCCGCCACCATGACGTGCATAGCCACCATACGTATCAACAATGATTTTACGTCCTGTTAATCCTGCATCACCTTGAGGTCCACCGATTACAAAGCGTCCTGTAGGATTGATGTAGAATTTAGTTTGTTCATTAATCAAGTTTTCTGGAACAGTTGGATAAATGACATGCGCTTTGATGTCTTCTTGAATTTGTTCAAGTGTCACATCATCAGCATGTTGTGTTGATACGACAATCGTATCAATACGTACTGGGTTATCATTTTCATCATATTCAACAGTGACCTGAACTTTACCGTCTGGTCGTAAATAATTTAACGTACCATCTTTACGCACATCAGATAAACGTTTTGCCAATTGATGTGATAAATAAATTGCTAGAGGCATGTACGTTTCTGTTTCATTCGTTGCGTAACCAAACATTAAACCTTGGTCACCTGCACCTGTTGCTTCAATTTCTTCTTCGCTATCTTTATCACGATACTCTAATGCTTTATCCACGCCTTGTGCAATGTCAGGTGATTGTTCATCAATCGCAGTTAAAATTGCCATTGTTTCATAATCATAACCATATTTTGCTCTTGTGTATCCAATTTCTTTAATTGTTTCTCTAACAACTTTCGGAATATCAACATATGTTGTTGTAGAAATTTCGCCGGCGATCAATGCCATACCTGTTGTAACAGTTGTTTCACAAGCTACACGTGCATTTGGGTCGTCTTTTAAAATAGCATCTAATATTGCATCTGACACTTGGTCAGCGATTTTATCTGGGTGTCCTTCTGTAACAGACTCTGAAGTAAATAATCGTTTGTTATTTAACATAGTTTGCTCCTTTAAATTTATATTACGAAAATTCTCTCTCTGTGAGCTAAATAAAAAAGACCTTCTAACTATTAATATAGAGAGAAGGCCTAATACGTCCATTCGCTCTTATCGTTCAGACCTATTTGTCTGCAAACGGTTTGGCACCTTTCTTTTATAAAAAAAGAGGTTGCTGGGTTTCATTGGGTCCATGTCCCTCCACCACTCAGGATAAGAGAATCCGTTAAAAATAATAGTACCTAATTAATGAATTAATGTCAATTTTTCACAAATAAATTTACAGTAAAATATTGTAGATTAATTATGTTAATGTGTTATACTAATTAAATGTAAAGGCTTACATTTAAATTATCGCTTTGGAGGGATTTAGGATGTCAGTAGACACATACACTGAAACAACTAAAATTGACAAATTACTGAAAAAACCAACGTCACATTTTCAACTTTCGACGACACAACTTTATAATAAAATCTTAGACAATAACGAAGGGGTATTAACAGAACTTGGTGCTGTTAATGCAAGTACTGGAAAATATACTGGTCGTTCGCCTAAAGACAAATTTTTTGTCTCTGAACCTTCATATAGAGATAACATTGATTGGGGAGAAATTAATCAACCTATCGATGAAGAAACTTTCTTGAAGTTATACCATAAAGTACTAGACTATTTAGATAAAAAAGATGAACTATACGTATTTAAAGGCTACGCTGGTAGCGATAAAGATACAATGTTAAAACTTACAGTCATCAATGAATTAGCATGGCATAATTTATTTGCTAAAAATATGTTTATTAGACCTGAATCAAAAGAAGAAGCTACAAAGATTAAACCTAACTTCACTATCGTTTCTGCACCACATTTTAAAGCAGATCCAGAAGTTGATGGTACTAAATCTGAAACCTTTGTCATTATTTCATTTAAACACAAAGTCATTTTAATCGGCGGTACTGAATACGCTGGTGAAATGAAAAAAGGTATCTTCTCTGTAATGAATTATCTCTTACCGATGCAAGATATTATGAGCATGCATTGCTCAGCAAACGTTGGTGAAAAAGGCGATGTTGCATTATTCTTTGGTCTATCTGGCACTGGTAAAACAACCTTATCGGCTGACCCACACCGTAAACTAATCGGTGATGATGAACACGGATGGAATAAAAACGGGGTCTTTAATATCGAAGGTGGCTGCTATGCAAAAGCAATTAATCTTTCCAAAGAAAAAGAACCACAGATTTTTGACGCAATCAAATATGGTGCAATTTTAGAGAACACTGTAGTTGCAGAAGATGGTTCAGTGGACTTTGAAGACAATCGTTATACAGAAAACACGCGTGCCGCTTATCCAATTAATCACATTGACAATATTGTAGTACCATCAAAAGCAGCACATCCAAATACAATTATTTTCTTAACTGCGGATGCATTTGGTGTTATTCCACCGATTTCAAAGTTAAATAAAGACCAAGCAATGTATCATTTCTTGAGTGGTTTCACTTCTAAATTAGCTGGTACAGAGCGTGGTGTGACAGAACCTGAACCATCATTCTCAACATGTTTCGGAGCACCGTTCTTCCCGTTACACCCTACTGTTTACGCTGATTTATTAGGTGAACTTATCGATTTACATGATGTTGATGTTTATCTTGTTAATACTGGATGGACTGGCGGAAAATATGGTGTAGGACGTAGAATCAGCTTACATTACACACGTCAAATGGTAAACCAAGCGATTTCTGGCAAATTGAAAAATGCAGAATATACAAAAGATAGTACGTTTGGTTTAAGCATTCCTGTAGAAATTGAAGATGTACCGAAAACAATTTTAAATCCAATTAATGCTTGGAGCGACAAAGAGAAATATAAAGCACAAGCAGAAGATTTAATTCAACGTTTTGAAAAGAACTTCGAAAAATTTGGTGAAAAAGTTGAACATATTGCTGAAAAAGGTAGCTTCAACAAATAAATTTGAATACTAATTAAAGAGCCAACCGTTGTTATAGTCTAACAATGGTTGGCTCCTCTTATTTTATGTGCTAAAAATTTATAGGCAATTTTATTACAACAATGCACATTTAAGGTGACCTTCATGCCAAACTCGCATCACTCATTTAATGGAAGCAGCACGTCTTCACATAAAGTACCGGTTCCTTACGCTATGCATGTTGCCCCACTTTGCATAAAGTACTTATCGTTAACTCAACGCAAGTTGTTCCTATTCACAAAAAGCACATACAGTTATCTGCATGGAGCACATTTTCATTGAAAGCGCATACCCCTCATTCAACGTATATCACACATCTTCAAAGCTTGATAGTTCCCATGCGCACACCACGTTTCATACTAGCTATGCAACTCAACTTGTTTCATAAACTCTTTAATATAAGTCAATGTTTCAACCATCGCTGGTGGTCTTGGCACATGTCCTTCTGCCATTTGATAAAATGTTTCATGCGTGGCACCTTTTAACTCTAGTTGGTCCGCTAAATAATACGCATGATGAATACCAACTTGCTGGTCTTTCCCTCCATGTACAATTAATATTGGCGGACTGTTTTCATTAATGTTTGGAATCGCTTGGCGTGCCTCATATGCCGCTCGATCTTTTTTCGGATGACCAATCATTCTTCGTAGCATGCCTCTTAAATCGACACGTTCTTCATACATTAAATCAATATCTGAGACACCACCCCAGATTGTATAACTTGTTACTGGTAAGTCTTGAAATGTCAACAATCCTTGTAAACCACCTCGCGAAAAACCAACCATGTGGATAAATGCATGTGGATATTTATCATGTAGCAACCTTAATAATTGCGTCACATCATTTAAATCGCCACGGTAAAATTCGTCTTTACCTTCACTCCCATTGTTACCTCGGTAGTATGGCCCAATCACTAAAGTTTGACTATCTGAAAATTGCATTAATCTACCTGCGCGCACACGTCCTACTTGACCTTTGCCACCTCGCAAATAAACTACAATGCGATTTACTTCATGATGTGGTGTCATCATTAAAGCTTTTACTTGTAAGTCATCTGACAAATATGTAATTTCTTCGAATTGATGCGTAAAAGATTCAATTGGCATTCGTTTACGTTTGATAAAATCCAAGTGATTGCACCCTCTCTACGCATTTTAAAATGGTACTATCTTGCAGTAAGAAACTCCGTTGTGCGAGTTCAATATCATTGATACAGTTAAACAACACTGGCCCTGCTGTTTCTAAATAATCGTTCTTGCTTACCAATGATTCAACTTCGATAAAATATACATCTTTTACAAAATCAGTTTGATCATGTGTTTCAATGGTATATTGTGCTATGTAATGAATATTTTTAACTTTGGCGCCTGTTTCTTCATATAATTCACGGGTAACTGCTTCAGCACTACTTTCCCCGCGTTCCCTTTTACCACCAGGAAATTCAATCCCCCGTAAATTATGTTTGGTAAAAAGCAATTGATTTTTAAACGTTGGAATAGCTAGCACATGATTGCCATCTGCTATCTCATTATCCTTTTTAAATGTCAAATTAACTTGACGATTATCTTTATCCCTAAACTTCACGCGCATCACATCCCTACATTGTATGTTAATATAATAGTTAATTACTATCGTTGGAGGCATTAATTATGAAAAAGATATTCTTGGCGATGATTCATTTTTATCAACGTTTCATTTCGCCACTCACTCCACCAACTTGTCGTTTTTATCCAACATGTTCAGAGTACACTAGAGAAGCGATTCAATACCACGGTGCTTTCAAAGGCCTTTATTTAGGCATCCGTCGTATTTTAAAATGTCATCCGCTTCATAAAGGTGGCTTTGACCCTGTTCCGTTAAAAAAAGACAAGTCAGCAAGCAAGCATTCACATAAACATAACCATTAATATGGTTGTAATTGAGTTATATCCACTAAAGGGGGGCGAAATTCGAGTCGCCCCTCTTTTAATATGCCTGATTTAGTAACCACATCTTGATCAAAATAATAACCTGCTGGTGTAACATCTCCTGGATAATCACCTTTACGAGCAAGCATCGCTGTAAAATAACGGCTTAAACCATATTCGTACATGCCGCCAATAACCACTTTTACACCATGACTTTTCAAAGTATCAATTGCCGTTTGCACTTTATCAATGCCACCTAGACGAAATGGTTTTAATACAACAACTTTCACATTGTATAATTCTATCAAATTAATTATGTCCAACAACGATGTTGCCTTTTCATCAAGGGCTATTGGAGGTATTGTTCCATCCACTACTTCATCAAGCATGGAGATATCTTTAAATGGCTCTTCGATATAAAGAACCTGTTCACGCGCTAATAGCTGTAACTGTGTGAAATCTTGACGATCCAATGACTCATTTGCATCTATAACCAATTGAAAGTGAAAGTCTAATTCCCGTAACACTCTAATTTGATGCATGATTTGAGGCGTCCATTTTAATTTAATTCTGGTCGGCTTTGTTGCTTTCAATGACTCTAGTTGTTTATTTGATAAGCCGCTCGCTGTCGCTCCATATGCTACTGAAAATGAAGGCAGTACATGAAACATTTGATACAATGCCATGACAATAGTTGCCCTTGCAGCAGGCGTATTTTCCAATGAATCTACTAATTTTAGTGCTGCTTCATACGTTTCAAATGATTTATTTCTATTATCTTCGAACCATTGCTCAATTACATGTTTCACTGAAGCAATTGTTTCATGATCATACCAATCTGTTTGAAAAGCGTTACATTCCCCGAAATATGCATTTCCTTTGTCATCAATCAATTCGATAAACAAACAATCACGATGCGTTAAAGTGACTTTCGGTGTTACAATTTGTGACTTAAATGGCTCACTATATTTATAAAAATGCAAAGCTGTCAACTTCATCAAATCATCCTCTATACAACTTATTTCTCTGTAATTTACCCGTTGATGTATAAGGTAAAGTATCAACCTTTTCAAAGTGTTTCGGTACTTTATATTTCGCTAAATGTTTTGATAAATATGCAATCAATTGTGCCTTTGAAATGTCACTTTCACTGACAAAATATAATTTAGGCACTTGGCCCCAAGTATCATCAGGATGCCCTACACATACTGCGTCACTGATACCTGGAAATTGCTTCGCTACCGTTTCAATTTGATATGGATAAATATTTTCACCGCCACTAATAATTAAATCTTTACGTCGGTCATAAATCATAACATAACCTTCATGATCTATTTCAGCAATGTCACCTGTATTAAAATAACCATTTTCAAACGTACCCGTTAAATCTGTTGGATACAAATATCCATTCATCACATTGGCACCTTTAATCATTAATTCTCCATGACCTTCTTTATTAGGATTTTTAATTTTAACGTCAACATTGGCACTTGGCATCCCTACAGTGTCAGGACGTGCATGCAACATTTCCGGTGTTGCTGTTAAAAATTGCGAACATGTCTCAGTCATACCAAATGAATTATAAATTGGCAGGTTATATTGTAATGCCGTCTCTATCATAGTGGCAGATAATTTAGCACCGCCGAGTAATATTTTTTGTAAATTATAAGGTTCATGTAAACCTTGTTGCATAAGCCAATTTAAAGTTTGTGGCACAAGCGAAATGTGCGTGATTCGTTCATTTTTAATCATCGTTAAAATTTGTTCGGCATTGAATTTATCAACAATGCGCACAGTAAAACCTTCAATAACAGCTCTTAAAAGTACACTGAGACCCGAAATATGATAAATCGGCAAGACAGATAGCCAATTAGTGTCACGATCAAATCCCAAGCTCTCTTTACATCCGATTGCACTGGCATAATGATTACGAAACGTTTGTGGCACCGCTTTTTGAGGGCCCGTTGTCCCTGATGTAAACATAATTGATGCAATGTCATCTAAATTAAATGATGTATTTAATATGTTGGACGGCGACTCTTTCGGCACCACAGTTTCATTCGATGTATCATATTGGATACCCATTGTGTTGTCCAACAAACCGTTCGTTGTAATATCCCTTCCAGCGAATTCAATATCATCCAGCGATACAATTTGAAACCCTCGCAATTCCAGTGGCAAGGTACAAAAAATCAATTGTACATCGATTGACCTCATCTGATTCGTCATCTCATTAGGTGTCAACCTTGTATTAATCATCGCAATTTCAATATTTGCCAACCAACATGCATGTATTAAAATGATCGATTGAATCGAATTATCTATGTATAGCCCGACACGAGATTGTTGATAAGCCTTGAGTCTTTTAGCCAATAGACTCGCTTCACAGTATAAATTTTGATAAGTATAAGATTCTTGACCGTCTGTTATCGCAATATGATGTCCATTTTGTTGTGCTTGTTTATATAACCAAAAGTCCATGCGTTATTCCTCCAAAATCATTTACATTATAATTATAACGATTTTATGACATTCTAGCAGTGGTTATGTTTAAAAATATAAAAAAGTAGACGAATTGATTCATTGATATGATTGTTATAATGCTCAATACATATCGTTATATCATTCGTCTACTATTATCAGTTATTTTTATTTAATTTTAGTGTCATTCTGTCATTTTGATGTGGTGATTTACCCATTGTTGCCACATCATCTGCAATGTCAATTGGTATACGATTCATGTCTTGTAATGCACTTAAATGGAATACTTCATCATCTAAATTTTCAATGAGATATACATAATATGTTACCTTGTCCTTTTTATATTTTAACGTTTTCCAAAAGTCCGGCTTGCAATTCAATACATTATCCGGAATATATTCAATAAATAAGTAACGTTTGCTGCCTACTTTGTCTATGAAATATTTTGCAGTGCCTTTTTCTATACCTCTTATATGTGCATAGTCTGCTGAAAAGTAAATACTACCTATTGTTTCATTATGTTGTTGTATTTCAAATCGTTGGCCTACTATTTTATTATTTGTGCCACAACTACTTAAAAAAATCAGTAGATATAGCATTAAACATATTTTCATCCCCTTGAATTTTAAAAACTTTTTCAAAAGCAACACCTCTAAAAATAAATACAATATATTATAGCAAATAGAAATTATTATTTTGTTAAATTATGTTGTCATGTTCGTGTCATTTTGAGTCGTAATACAACTTTACAATTATTAAATTAACACTTCTACAATCCAAAAATATTTTTAAAGTTTTGAAAAAAATTAAAGTATTTCCACTACTAATTTGGTAAAATATGATTATGTGATATAGTGAAAGCGTTTTACACTTAATAACTCCCTCTTAAATGCATCCAGGTTTTATGTAGTAAATCATGAAAATAACATATAAATATAGAGGAGATTTACCTTTGAATACAGAGAACAACAAGAATCAAAACCAATCTGTTAAAAATTCTGAAAGACGCGGCATGTTAAAAGGATGCGGCGGTTGCCTTATTTCTTTTATTTTATTAATAATCTTATTATCAGCCTGTTCAATGATGTTTAGTAATAATGACAATTCCACTAGTAATCAATCATCAAAAACGCAATTAACTCAAAAAGATGAAAATAAAAATGAAGATAAGCCTGAGGAAAAATCAGAAACAGCTACAGATGAGGATTTACAATCAACCGAAGAAGTACCCGCAAATGAAAATACTGAAAATAATCAACATGAAATTGATGAAATAACAACAAAAGATCAATCAGATGATGAAATTAACACACCAAACGTTGCAGAAGATAAATCACAAGACGACTTGAAAGATGATTTAAAAGAAAAGCAACAATCAAGTAACCATCATCAATCCACGCAACCTAAGACCTCACCATCAACTGAAACAAACAGGCAACAATCATTTGCTAATTGTAAGCAACTTAGACAAGTTTATCCGAATGGTGTCACTGCCGATCATCCAGCATATCGTCCACATTTAGATAGAGATAAAGATAATCGTGCATGTGAACCTGATAAAAATTAAACAACAAGCGAATTGAATTCAAATTGTATTTAGCTTTATGCACTAATCACATAGTAAATAATGAGGGAGATTTTTTAGGCATGAGCAATCAATTCAAAAGTGAAGAAGAACGAAGACAATGGGAACAATTCCAAGCTTTCCAAAATCAACAAAACCAACAGCACCAGCAATACGGACAAAAGAAATCTAAAAAAGGATGGTTCTGGGGTTGTGGTGGTTGTCTAGTATTATTTATTTTAATTATCATCGGTATTTCAGCTTGTACAGCTGGTGTCACTGGTAACCTTGGTGGAAATAGTTCTAAAGAAGCGAACAAAACCCATAAAATCGGTGAAACTGTTAAAAATGGCGACCTTGAAGTCACTGTAAATTCAGTGGAAACTATGAAATCTGTAGGACCGTCTCTTGCACCAACAAACGCTAAAGGTATATTTGTCGTTGCTGATGTGACGATTAAAAACAAAGGTAAAGAAGCGTTAACAATTGATAGTTCAATGTTTAAGTTAAAATCCGGTGATAAAACATTTGAAGCAGATAATACAGGTTCAATGTCTGCTAATCAAAGTGACAATGGTAGTATAGAAAATTCATTTTTCTTACAGCGTATAAATCCTGATAGCACTGCACAAGGTAAAATTGTTTTCGATGTGTCAGAAAACATAGCCAACGCAAAAGATAAAAAATTAGAAGTTATTTCTAGTTTATTTAGCGTCAAGAAGATTACATTTGATTTATCCGATGCTAAAAAAACATCAAAAGCTAAAAAAGACAAGCAAGATACAGAAGTAGCTGTTGCGAGTTCAAATAGCGATAATGTAAATTATGAAGCTTCGGCTACTACACCTGCTACAACTTCTAGTGCGGATACTGATTCTGAAGATAGCGAAAAGTCTAGTAAAGATGAGGATAAACAGAATGCGTCTAAAAGTGATAAATCTAGTGTAGAAAAAAGTGAATCTAATGAGGAAACTGCTACTGTAGAGCCCATGCCCCAGAGCAAACCTACCACTAGTGAAGCACCACCTAGTCAAAATAATCACAACGAAAATAACATGTATGATGCTTCAACAGAATAAATTTTCAGGGTAGCTCAGCTACCCTTCTTTTTCGGTAAAAATAAATATACATAGCAATATAAGGAGATTAAAAAATGAAATTCAAAGCTATCGTTGCAATCACATTATCATTTTCACTATTAACTGCCTGCGGTGCTAATCAACATAAAGAAAATAATAGTAAATCAAATGACACTACTAAAAAGACGCAAGAAACTGACAACACTACACAGTCAAATACAGAAAAGCAAATGACACCACAAGAAGCCGAAGATATCGTTCGAAACGATTACAAAGCAAGAGGTGCTAACGAAAATCAAACTTTAAATTATAAAACAAATCTTGAACGGAGTAATGAACATGAATATTATGTTGAACATCTAGTCCGCGATGCAGTTGGCACACCTTTAAAACGTTGCGCTATTGTTAATCGACACAATGGTACGATTATTAATATTTTTGATGATATGTCAGAAAAAGATAAAGAAGAATTTGAAGCATTTAAAAAGAGAAGCCCTAAATACAACCCAGGTATGAGTGATCATGATAAAACAGATGGTGAGTCAGAAGACATTCAACATCATGACAATGATAATAACAAAGCCATTCAAAATGATACACCAGATCAAAAAGCCGTTGATAAAAACGATAAAAATGCTGTTAATAAAGAAGAAAAACATGATAACCATGCAAAAAATTCAGCAGAAACTAAAGTTAAATAAGGGTATACTTTGATTAATTGTAATTTTTAGGAGAAAAACTATGATAACATTTGAGAATATACAACAACTTGAAAAATACACCTTAATGACTATGCATGGTCTTTTTAATCAACTTAAACTCGGTATTATTTCAATCGACAATGCAGAGCATACCCTCTTTACACCTTATATGATGGAATCACTCTCTTCCCTAGGTGTGAAACCAGACATTATCGATTTAATTCACAAAGGGACAGAGTTAGAAGACTTTGCAGCATTTAATTTATCAATTGAAGATACAGTTACAGTCTGTTTACAAAGAACTGAAGAACTATTAAATCAATACAAAAATGTGGAATTCAATGACAAAATATTAATCAATTGGCGTATTATACAAGAGTAATAGACATATAAAAGTCGAATGTAACTACGTGAGTACTGATTTTATTCTTTGTAAATTACAAGCATTTCATATCATAAAGTTTGAAAAGAGGTATATTGAAGTGGAGAAAAACGAATATACAGCTAAATATAATGAATATAGTCAATTATTAGACGCTACTTACTCGCAAGCTGTAGCATACCTTTTAAATAAATATGGCGCTGTAACCGATGATTATTATAAGGAAAAATCATACACGCGATTTTTAAATGGAGAAATCAAAAGTATTTCAAAAGGAAAATACACTAGAGCTAGCGAAGGATTATATTGTCATCACATAAGCGAAGACAAATTCCAAAACTTATCTGACCTAAGATTCATTTCCGAATTTAAGTACTCATACAACGTTCAAAAGAAAGAAAACTTAGTGTACTGTGATCTAATCGAGCATTTAATTTTACATGCAATTATTACAAAAGAATCCAATGGCCAATTTGGTGTGGCTGGATTATGTCAAATGATCAAACCAACAGTCATTGATTGGTACATTAGCGAATATACTCCAAAACCAGCATGGATGCAAGCCACCAAAGCACGTGCCTATTTGCCTAGAATATTAGTAGAGAAACTACTCATTAAAATTGACGATATGTTAGAAGGAATAGAAATATATGATTTCCTTGAGTCTAGATAAATGATTAATGGAGATTTATTTTTTGCTGTTGAGATTTTGTTATAGATGTTTAAACCTGTAATTAAATATATTTTATAAAATAGACCACGCATACCTATCTATAAACGGACAATGTTTATAAATGAGTTTGCATGGTCTTGAATTGTATTAAATTTCTTTTGGTTTTAATAGTTCACTTAGTGGTATGTCAACATTTTTTAGACAGTTTTCATGTGTATATTTTTAAATGCCACTGGCGTCAAATACTGTAATGAAGAATGTGGTCTAAAATTGTTGTACCAATTTACATAATCAAATAATTCTGTTTCTAACTGTTCTAAGTTTTCAAATTGCATTTGTTTTACAAATTCTGTTTTCATTGCTTTCATCGTTGCTTCCGCAACTGCGTTATCATAAGGACAACCTTTGGTACTTAATGAACGTTTTATTTTAAATGTTTCTAGGACTTCATCTATCAAATGATTATCAAATTCTTTGTCTCTATCAGTGTGGAATAGTTTGATTTGTTCAAGATTATGATTTATTCTGCTGATTGCTTTTGATACTAAATTGGCGTCCTTATTTTTACCTGCACTGTAACCAACAATTTCTCTATTAAATAGATCTATAAATAAACATATGTAATGCCATGTTCCTCCGACTTTTACATATGTCAAATCACTTACTAATGTCTCCATTGGTTGTTCTCTATTAAAAGCGCGATTCAAATGATTTTTAATTCGTTTTTCATTAGTTTCTATTTGATGATTTTTGTATTTAGCTTTCATATAAACAGAAACTAGATTTTTTCATAATCGACCTATCTTTTGTCCAGATACAGTGAGACCCTTGTCATTTAAATGATTTTTAATTCGTCTTGTACTAAAGACTTTTCTATTAGAATTAAAAATATTTATGGCGGCACGTTCTACGTTTGAATCATCTTTAGTGATTTTATTATCTTTTCTTTTTATAGAATCATAATAGGTACTTCTTGGTATTTTTAGGACTTTACACATTGCTGGTACTGAATATTGATGTGCATTCTTTTGAATGACTTCTATTTTTGCCCCATAATCAGCTCTTTTTCTTCATCTGTTAAGTTATCTTGGTGATTGAATGTACCCTTGTTTTGATGTTACTTTATCCATTTTCCTAACGTCAAAGGTGTTAAATCATACTCGCGTATAATTTCATTTCTTGGCTTACCATTTTCATATAATCTAACCATTTATAACTTAAACTCTGAACTAAATGTTCTTCTTTCTTAAATTAACAAAATCTACTCTCATAGAATTTGTCCAATTAGATGATATAATAGTAGAGTCGCCTATCTCTCAGGCGTCAATTTAGACGCAGAGAGGAGGTGTATAAGGTGATGCTTATTTTCGTTCACATCATAGCACCAGTCATCAGTGGCTGTGCCATTGCGTTTTTTTCTTATTGGCTAAGTAGACGCAATACAAAATAGGTGACATATAGCCGCACCAATAAAAATCCCCTCACTACCGCAAATAGTGAGGGGATTGGTGTATAAGTAAATACTTATTTTCGTTATCTCAATTATACTGCTAATCTTTCTCTTTGTAAAATATGCAAGGTTTTAAAGAGAAACATCAAGAACTAAAAAAGGCTCTATGCCAAATTGGCCTGATGAGTTCAATATCGGAAGTTAGGCAACTAAACATTGCTTAGCTTCCTTTTTACTTTTTGGAGCGTAAAGTTTTGAACATAATAATATTCGATTTCGCAAATGATTATAACTTCCTTAACCAAAAGATGTACGTTTAATTAATTTTATTTTGTTGTTTATCCCTTCTAAAGGACCATTTGATTATCCTTCGTTTTAAAGTTAATGCCTTCTTTCCAGTCAAACTGTGCTTGATGACTGGCTTTTGTCTCGAATCTCGTTTTGCCTTTAGGCGACAACCGTTGATAACCTTTCATAAAATAACGATTAAATTCATCATGTTTAAGGATATAAGCTCTAAATGTAGAATATGCACAGGTTAATCCATGTTTATCTTTCAAATATTGCCAAAGAATAAGCTTATAGTAGAACTTTTGTTCACTAGAGTCTGAAAGTAATTTTTCGATGATAGGATAATACTTGTCAATAATAGACTGACGATTTCTCTTTTTGGTTGGCTCAAAGCCATTTAAATATTTATCAACTGTTCTTCTATAAACACCCATGTGTCTCGCTATTTCACTTTTGTTTATTTTCATGTTTAAGTTCTCCATGACAATTTTTAATTTTGGTAAATCTGTAAGAGTAGTAACTTCAAAATCAGTATTTATGTCTAAAGATAATTTCATTGTTGTTCATCTCAATAAAATTATCTATAGGTTTTTAAAAATTGTACATGTTTAAACAATCAAAAGTGCACATTATTAAATTATCATTTCCAGTTAAACTGTCTTGATGATTGAATGACTCAGTATTTTGGTTTTGTTTTGTCTAATTTGAGAGAGTTAATGATGTTAGATTATATTCTCGTATAATTTCGTTTCTAGGCTTACCATTTTCATAAAGTTTAATTATTTTAATTTAAATTATTTACTAAAAGCTCTTCAGTCTCTTGTCACAATAAAATCGCCTAACCTCTTAGTTTAACAATATCTATTCCCATAGAATTTGTCCAACTAAGTGTAGACGATTCACTAAACTCCAAAAAAATAAATCCCAAATTATAATAGTTTCAATATTAATATATTACAATTTATTCATAGAATTTTTATCATTTTAATTAATAGGCTGTTATCTGGATTAAACAAACATTTTTTGTAATAGTTCTTTTTTACGTACTTTTAATCGTCCGACTTTTGAAGATTGTTTTTCAACCAATCTATCTATTTCACTGAAAAAATCACCGATTTTTTGTTGTTCTTCATAAGATGGCAATTTAGTCTTTATGTTTTGCAAGTCTTTTTGTGAGAGTACCAATTGTGATGTACCAGTTGCATATTTAATATATTCTTTTTTCAGTTGATAGTTTAAGTGTAATGTTAAATAATATTGATTTGCATCTATCCCTTTAAAGACAGGGTAATATTTACTAATAATACCTACATCAATCATTAGATTTAAATTAAACTTAAAAATTCCATCGTCGCTTCTTGAACGGTATGTTATATGATTTTTAGGGAGTATGAAATACCCAATATTACTCTCTGCAAAAGTTTTCCTATCTTTATAGTAGTCTGACTGAAGTATTAAACCTTGTCTTGACGATGTTAAAACAGGATATTCATTTTCATTAATAGTTCTTTTATTACTAAATTCTAATACATCTTTTAATTGCTTTTTGTTCCATCCTTTATAGTAATTACCTTCTTCATCTTTGAATCGTAATTCTTGTGAGAAGATTTTCTGTATATAGCATTTTTTCTGTTGTTGAAGTAATTCAAGTTTTTGTTCTTCTAATTCAATTTGTTGGTCAAGTTTGCTGAAGAATTGTCCTATTTTTTGTTGTTCTTCAAATATAGTTGGGGTGAAGATTTTTAAATTAGCAATTTCTTTGAAGTTTAGTCCTTCTCGACTACCTCCACTTTGTGCAAGGAAAATTTTTCTTTTACCTTTTCTTGATAATAGATACTGTCCAAAAAAATTATAATAATACTCTTTTTTTAATCTAATAATACATACATGTTGATTTAAATTAGCATGCGTTTCAACTATCGAATTAATGGCTGTTCTACCTATTGATGCTCCTGTAATATTTAAAAGAACATCACCATAGTACGTTCTACTATTTTTCATCTCATCATCTATATCTTTACTAATATAAACTAAGTCATTAAGATTTAATTTACCATTTCTAATATTTTGACTCCTTAAAAATGGTATGCCTTTGTTTGTATAGTTTTCACTTCCACCTTTGGGAGTCTTTCCACTACCTATTTTGGTAGTAAGATTCCCTAACTTCTTCTCTTCCCATTCGCCCTCAAATCCTGGGAATCTCAACTCTGGCACATTTTTCGTTTGTGTATTACTCATCTTTCAACACCCCAAGTTCTTTCAGGTATGCATTGATTTCTTGTTCAATTTCTGCGATTTCTTTGTCGATATTTTTCAAATCTTGTTGGACTTGATCTAAATCAATTGGTGCTTCTTCTTCGAATGTATCAACATATCGCGGTATGTTTAAGTTGTAATCGTTATCGGCGATCTCTTGTAATGTCGCGCTGTAGCTATATTTATCAATCGTTGCTTTACGCTTATATGTGTCTATAATACGTTCGACTTGGGCATCGCTTAAATGGTTTTGATTTTTTCCTTTTTCAAAATCATTGGATGCATCGATAAATAGTACGTTGTCGTCTTGTTGGCGACATTTTTTAAATACTAAAATACATGTTGGAATACTTGTCCCATAGAAAATATTGGCTGGTAACCCAATCACGGCTTCTAAGTAGTTCTTTTCTTCTATTAAATAGCGACGAATCACACCTTCTGCGGCACCACGGAATAATACACCATGTGGGAGTACGACTGCCATGGTACCTTCATCGTCTAGGTAATGTACCATGTGTTGAATAAAGGCAAAGTCTGCTTTGGATTTTGGCGCAAGCTTGCCGTAACCACTGAATCGTTCATCATTTTCAAATTTTGAATCTGCTGTCCATTTCGCACTGTATGGTGGGTTCGCAATAACCGCATCAAATGTATTGCCTAAAAAGGCTGGATTTTCCAATGTGTCATCATTACGGATCTCGAAGTTCTCATAACGCACATCATGTAATAACATATTCATGCGTGCTAAGTTGTATGTAGTATTGTTACGTTCTTGTCCGAAATAACGATACACTTGCGTTTCTTTACCAACACGTAACAACAATGAACCGGAACCACATGTTGGGTCGTACACGTGACGTAATTTATCTTTACCGTCTGTGACAATCTTCGCCAGTATCTTAGATACTTGTTGTGGTGTATAGAACTCGCCTGCTTTTTTACCCGCTGTCGCCGCAAAGCGCCCGATTAGGAATTCATATGCATCACCTAACATATCAATTTCCATGTCACTGTGAACGAATGGTAAGTCGTCAAGATTAACCATGACTTTAGAGATTAAAGCAGTACGTTCTTTGACATTGTTACCTAGTCGCGTTGAACTCAAATCCATATCGCTGAACAGCCCGATAAAGTCATTTTCACTTTCTTCACCTAATGTAGATGTTTCAACTTTGCGAATCGCCGTCGCTAGATGTTCTATATCGAAATCTTGCGTTTCAATTTCACGAATCATCGCACTGAATAAATCTTGTGGCTCAATGAAGTAACCGACTTGATCAATTAATTCTGCTTTTAAGTCTTCACGATATTCTTCATCTGCCCATGCTTCTTGATACGTGATGTCTTCACCTGACAAGGCATCTGCATATTCTTGTTCGGCTTTTTCAGATAAGAAGCGATAGAAAATCAAGCCTAAAATGTAATTACGGAATTCACTCGCATCCATGTTCCCTCTTAAATCATTCGCAATCGACCATAATTTTTTATGTAATTCAGCTTGTTGCTGACGTTGTTTTTCAGTAATAGACATGTGATTCCTCCGCCTTTGCATAAGTAATTTATCTCTTTGTGTAATAGATTTATTATAACATTTGGTTATGTTGCGATGTTGATAATTTGGATGTTGGTGGTGGAAATTTTGAGTTTTAGTGGCGCAATTGTTATTGAAAAATTTTATAGAAATGTTGTAGCTTTCAAATGCTTTCAAAATCATTTATATTCTTAATGATGTCAAAAAGTTGTTCATTCATACATAAATAAAACCAATCAACAATTGAGTTGGTGAAAATCAATCGTTGATTGGCTTTGATGCATATTAAATAATGCAATATATTAATAAATGTTAGTTATAGTATATTTTGTCAGGATTGGGTGAATGTCTAAGTTTTAATTATTTATCTAAATTATCTGCAATGAATTTCTTAATTTCAGGAGAGAAATAAACAGCAAATCCTCTTGTGCTTTCACCTGATGGCTTATTACCGGCATAGATTACACCAATAGCTTCGTGTTTACTATTTAATATAGGTGAACCAGAGCTACCAGGCTGAATAATTGCATCCGATGACACTATATTCCCATTCACTGATAATACTTTACCAGTTGATTCATACATTTGTAGTTTATTTCCATTAGGATTTGGATAACCAATGACTGATATAGGTTCATTTTCTTTAGCTTCTGATGCTATATTAAATTTACTAGTGAAATCTTTGAATTTTCTACCTTTTGGTTGTGTTGATTTTTCTTCAACTTGTACAACCGCAATATCTTCTTTACCAGGATAATCTACAATCTTAGTAACTTTATAAAGTCCACCACCGTTATTATAAAAACCATTAGGATGTGCTTTGATTTCATCACCGACTTTCATGTGATAGGTAACATGTTTATTGGTAATGATTGTATGATTTCCAACTACAAATCCTGTTCCAGCGCCCATCCATGTAACACCACTGTATGGTGCAACATTTGTATTTGTAATTTGTTTAACAGTATTTTCGGCTTTGGCTGTTTGTTGAATACCTTCAACCATTGTTGTGCCGACGCCAGTCACTGATGTTAAAATCGTCAATGCTGCAATACTTTTGATGATTATATTTTTATTCATTTTTGTGCTCCTCTAAGTATTCGTATAAATATAAGGTTAGGTTTTTGAAGTTTTATTTTTTAAATCATTTCGAATAAATAGAATCACAGAGATGTTTAAAATTGTTGATTTTGTTGTTAATTTCTAAAAATCATTTATCAATGTATGGATGGATGATTTATTTATCTAAATTATCTGCAATAAATTTCTTAATTTCAGGAGAGAAATAAACAGCAAATGACCTTGTACTTTCACCTGTTGGTTTATCACTAGCATACATAACACCAATTGCTTCTCGCTTACTATTTAATATAGGTGAACCAGAGCTGCCAGGTTGGACAACCGCATCAGATGTCACTATATTTCCATTCACTGATAGTACTTTACCAGTTGATTCATACATTTGTAGTTTATTTCCATTAGGATTTGGATAACCAATGACTGATATAGGTTCATTTTCTTTAGCTTCTGATGCTATATTAAATTTGCTAGTGAAATCTTTGAATTTTCTACCTTTTGGTTGCGTTGATTTTTCTTCAACTTGTACAACCGCAATATCTTCTTTACCAGGATAATCTACAATCTTAGTAACTTTATAAAGTCCACCACCGTTATTATAAAAACCATTAGGATGTGCTTTGATTTCATCACCGACTTTCATGTGATAAGTAACATGTTTATTGGTAATGATTGTATGATTCCCAACTACAAATCCTGTTCCAGCGCCCATCCATGTAACACCACTGTATGGTGCAACATTCGTGTTGGTAATTAATTTCACACTATTTTCTGCTTTGGCTGTTTGTTGAATACCATCAACCACTGTTGTGCCGACACCAGTTATTGATGTTAAAATCGTCAATGCCGCAATACTTTTGATGATTATATTTTTATTCATTTTTGTGCTCCTCTGTTTATTCATGATGCTTTTGATATAGACGTTTTTTTATGTTATATTCGACCGATGTTTTTCATTAAAATTATTGAACACATGCTCATGGTGTATATTTAAATTTGTTTATTGTTCAATGTGCTTTTGAATAAAATCTTTGATTTGAGGCGTAAAGTATACGGCACCATTATATTCAGAACCAATTTTTCCAATACCGCCATACACCACACCTATGACCTCATTGTTAGAATTTAGAACTGGTGATCCTGAATTCCCGGGTTCAATGTATGCATCAAAATTTAAAATATTGTCTTTGATTCTTTTTATAGTTCCTGTAGATTCAAACTGTTTAAAACTATTTTGAGCAGGTAATGGGTAACCAATAACTTTAATTTTGTCATCAACTTTAGCATCTTTCGCAAAATTGAATGCTTGGACATTTTCATTAAAATTAAAGCCTTTTGGTCCACGTTCAACTGCTTGTTCTTCAATATTCATGACAGAGATGTCTTCATCACCCGGATAATCAGAAATGCTTTTAATTTTATATATACCACCATTTCCTTTGTCACCGTTTGGATGGGCAGTAATTCTATCGCCAACTTTATAATCTTTTGATACATGTTTATTGGTGATAATTGTATTTTTTCCAATTACAAAACCTGTCGCATCCTTAAATGAAACGACGCCATTATATGGAAAATTATTTGTATCTTTAACTTGCGTAACATTCTTCTCTGCATTTGCTATTTGTTGTGTCTCTTCAACGACTGCAGCATTTATTCCAGTTACTGAGGTTAGAATGGCTAATGCTGCCATGCTTTTAATGACTATATTTTTATTCATTTTCAAGCTCCTTTACAATTCGAGATATGTTGCAACGCTCGTTTAAAGTCAATTTGTTTATTTATCTATGTTTTCTGCAATGAATTTTTTAATTTCTGGTGTAAAGTAGACGCCATATGCATTTCTGTTATCATCATTTTTTACATCAGAAGCAAAATGAATACCAACTAATTCGTTGTTGCTGTTTAATACAGGTGATCCAGAGTTTCCGCTTTCAGTATGCGCTGAATATACAATACTGCTACCTTCTACTGACATCACAGGGCCAGTTGACTCATATAAAACATATTTATTTTTGTATGGGTGTGGATAACCAATCACTTTAATTCGCTCACCAGCTTTAGCCCCTGCCGCATATTTGAATGGCGTTACATTATCATTAAAATTAAAGCCTTTTGGTCCACGTTCTATTGCACGCTCTTCAACTTGAATGACTGATACATCTTCTTTACCTGGATAATTAATAATCTTTTTAATCGAATAAATACCACCATTACCTTTATCACTATTTGGATGTGCAGTAATACGATCGCCCACTTTGTAATTTTTCGACACATGTTTATTTGTTAAAATAGTATTCTTTCCAACTACAAATCCAGTTGCACTTTTAAAAGCAACTACACCAGTATATGGAAAAATATTAGTATCTTGAATTTTTGTGACATTATTTTCTGCTTTGGCAGTTTGTTGAACTTCCTCAACCAATGTTGTTCCAATACCTGTTACAGATGTTAAAATTGTTAAAGTTGCTAAACTCTTGATGACTACGTTTTTGTTCATTTTAAGTTCCTCTTTTTTAATTATTTTGATATCTAGATACATAATTCAGTATATTTAGTTGGTTATGTAACCGTTTTCTTAATCACTCTTTAAAAAATCAACTTCACGAATGAATTGATGATACTTATTTTTCAATATTATTTTGAATAAATTCTTTTAATTGTGGTGTGAAATAAACACCGAAATTCTTTTCAGATTCATCTTTTCCACTACCTGCATATAAAATACCAATCAGTTCATGTTTAGAATTCAATACAGGAGATCCTGAATTACCTGGTTGTGCATACGCATCAAATTCTATAAACGTTCCACTGATATGGTTAATCGTTCCTGTCGATTCAAACATTTTATATTTTGTTTGTGCACCCTTTGGATAACCAATAACAGAAATTCTATCTTTCGCTTTTGCTCCTTCTGCAAATTTTGTATAACTAACGTTCTTATTAAAATTCAAACCTTCTGTACTTGTTTCATGAACATGAACTATCGCAAGGTCTTCTTTTCCAGGATATTCTACAATGTCTTTAACGTCGTAGTTTCCTCCGCCTTTACCTTTACTCGAATAATGTGCTGCTACTCTATTTTTAAAAATATCATTACTTTTAGCGATATGTTTGTTAGTTACGATTGTATTTTTACCAACAACTACACCAGTACCACCCGCAAATGCTACCACTGAATTGTATGGTGCCTTAGTTGCATCGGTAATTTCTTTGACATTCTTTTCTGCTTTGGCAATTGAATGAGGCTGATTAGAAATATTTTCAGCGAAACCAAGAGATGTTAAAATAGTTAAAGCAGTTAAACCTTTAACCATTACATTTTTATTCATATTTTACCTCCTTCCAAATTTATTTTTATAGTTAATGTATCTAGATACACATTTACTATATACATTTTAAATAAAAATATTAATTAAATATTAATTAACCACTTATTAACATTTTATTAAATAATTATACATGAATTGACTCATTTATTTAAATATGCTTAAAACTCAATATCACGCAATTAAAATTGACTTTTTAGGATTATTTTGGTCTTAAATATTAATTATTGAATTAAAATTGTAATATTTATTCGGAAATTAGGTAATTGAAAATATATGGCGGAATGGTGAACAATTCATGTATTTAAAATCTTTCACTTTATTATGTATTGTGTTTAACAATATTATTAGCGATTAGTTCCCCTATTATTTATGACAATATGCAGTCAATCAATGAAACATGTATGTATGAGTATATTTGGAACTAGTAATGTATTGTTAATTATTGAAGATGATTGAATTATGGAATTTTTTTCGAGATATGTTATTTCGGGGATCAGATTTTGCGATTTCGCCTTGGATAGAGTAGTTGCGATTTGTAAATACGTTTTTCAGGTTCGATTCAATTTCGTTGTTAAGATAATATGGATTAGTTTCACTGACATGTTGATGCATGTCTTTTTTGTTCTGATAAAGTATAAAATGTTTACTTAACATTACTTAGTATGACACCTGCTAATTCAAACATTATTTGAGACATTCTTTTCAAATTAATTATAAATTTTTACCTATAGACTAGTTTGATATTTATCTACATCTCAAAATTCTCATCAACAATCTTTCACATCCAACATTTTTACTTTAGTTTTTATAATTCAAAACAACAAAACGATGTTAAAAAATTATTCTATTTTTTAGTTAATAGATAGTTAATACATTTTTGATATTTAGTTAATTGTTCTTTTAAAAAATATTATTATATTTTCATTGTAAACGTTTACAATATAAAAAAAGGAGCAATTAAAATGAATACAAAATTTTTAGGTAAAACATTAGTAGCAAGTGCTTTAGTATTAACAACATTAGGAACAGGTTTACATTCTTCATACTTAGGATTAAATACAAATAAAGTTGTTAAAACAGCAAAAGCAGAAGAAAAAATGACAAATGGTCAATTGTGGAAAAAAGTTAAAGATTCATTAATTGATTCAAATATTATTAGTGGTAACGAAAATGAAGAGATTACAGTAACATATGTTAATAAAACCGGATATTCTTCAAGTGTTTCTGCCTATGGTAATAATAATGACGATTTTTCAAGTACTCCAAGTAATTTTTCTAAACTTAAGGAAATTGACTTGAAAAAAGATAATGTACCGTCAGATGATTTTAATACTACTGTTAGTGGTGAAGATAGTTGGAAAACACTTACATCTAAATTAAAGGAAAAAGGTTTGGTTACAGATGGACAAACAGTAACTATTCATTGTAATGATAAGTCTGACAATACAAAATCATCTGTTTCAGGTAAAGTAGGAGCAGATCTGACAAGTGGCAATGGAACTACATTCAAAAAACGCTTTATTGATAAAATCACAATTGATTAA

Protein sequences of DBSCAN-SWA_4

>NC_002745|1808959:1866661|1851697_1852348_+|WP_001795210.1|DBSCAN-SWA
MKITYKYRGDLPLNTENNKNQNQSVKNSERRGMLKGCGGCLISFILLIILLSACSMMFSNNDNSTSNQSSKTQLTQKDENKNEDKPEEKSETATDEDLQSTEEVPANENTENNQHEIDEITTKDQSDDEINTPNVAEDKSQDDLKDDLKEKQQSSNHHQSTQPKTSPSTETNRQQSFANCKQLRQVYPNGVTADHPAYRPHLDRDKDNRACEPDKN
>NC_002745|1808959:1866661|1841139_1841973_-|WP_000453306.1|DBSCAN-SWA
MEVKTFYNGNTMPQIGLGTFRVENDENCMESVKYAIEQGYRSIDTAKVYGNEEQVGAGIRAGLESTGIAREDLFITSKLYFEDFGRENVAAAYEASLSRLGLKYLDLYLVHWPGTNEAVMVDTWKGMEDLYKNNKAKNIGVSNFEPEHLEALLAQVSIKPVINQVEYHPYLTQHKLKLYLAAQHIVMESWSPLMNAQILNDETIKDIAQELGKSPAQVVLRWNVQHGVVIIPKSVTPNRISENFQIFDFELSDEQMTRIDGLNQDKRIGPDPKTFEG
>NC_002745|1808959:1866661|1821124_1821688_+|WP_000764419.1|DBSCAN-SWA
MKLERILPFSKTLIKQHITPESIVVDATCGNGNDTLFLAEQVPEGHVYGFDIQDLALENTRDKVKDFNHVSLIKDGHENIEHHINDAHKGHIDAAIFNLGYLPKGDKSIVTKPDTTIQAINSLLSLMSIEGIIVLVIYHGHSEGQIEKHALLDYLSTLDQKHAQVLQYQFLNQRNHAPFICAIEKIS
>NC_002745|1808959:1866661|1821810_1822212_-|WP_000757543.1|DBSCAN-SWA
MKKVNNDTVFGILQLETLLGDINSIFSEIESEYKMSREEILILLTLWQKGSMTLKEMDRFVEVKPYKRTRTYNNLVELEWIYKERPVDDERTVIIHFNEKLQQEKVELLNFISDAIASRATAMQNSLNAIIAV
>NC_002745|1808959:1866661|1833646_1833871_-|WP_000384171.1|DBSCAN-SWA
MDYAHLNLEHFFARNDDLDVIRDRADFVMINNFTNEMMYRDGQIEGTIDLNQYYYKNRSNAASFIMMDYKKETK
>NC_002745|1808959:1866661|1827274_1828318_-|WP_000077358.1|DBSCAN-SWA
MSQFMDYAIQLANMVQGQTGVNPPVGAVVVNEGRIVGIGAHLRKGDKHAEVQALDMAQQNAEGATIYITLEPCSHFGSTPPCVNKIIDCKIAKVVYATKDNSLDTHGDETLRAHGIEVECVDDERASQLYQDFFKAKAKQLPQITVKVSASLDGKQANDNGQSQWITNKEVKQDVYKLRHRHDAVLTGRRTVELDDPQYTTRIQDGKNPIKVILSKSGNIHFNQQIYQDESTPIWIYTENPNLTSNQTHIEIIYLKSCDLTTILHNLYKRGVGTLLVEAGPTTTSEFLQSNYIDEFILYYAPKLIGGSGNYQFYQTNDVIEIPDANQFEIVHSELLNQNVKLTLRKK
>NC_002745|1808959:1866661|1857929_1859159_-|WP_000072627.1|DBSCAN-SWA
MSNTQTKNVPELRFPGFEGEWEEKKLGNLTTKIGSGKTPKGGSENYTNKGIPFLRSQNIRNGKLNLNDLVYISKDIDDEMKNSRTYYGDVLLNITGASIGRTAINSIVETHANLNQHVCIIRLKKEYYYNFFGQYLLSRKGKRKIFLAQSGGSREGLNFKEIANLKIFTPTIFEEQQKIGQFFSKLDQQIELEEQKLELLQQQKKCYIQKIFSQELRFKDEEGNYYKGWNKKQLKDVLEFSNKRTINENEYPVLTSSRQGLILQSDYYKDRKTFAESNIGYFILPKNHITYRSRSDDGIFKFNLNLMIDVGIISKYYPVFKGIDANQYYLTLHLNYQLKKEYIKYATGTSQLVLSQKDLQNIKTKLPSYEEQQKIGDFFSEIDRLVEKQSSKVGRLKVRKKELLQKMFV
>NC_002745|1808959:1866661|1820174_1821128_+|WP_000526539.1|DBSCAN-SWA
MGNHFQYAFENKRYHTWNYHLKNKFGQKIFKVALDGGFDCPNRDGTVAHGGCTFCSAAGSGDFAGNRADSIAVQFKEIKEKMHEKWHEGKYIAYFQAFTNTHAPVEVLKEKFEPVLKEPGVVGLSIGTRPDCLPDDVVEYLADLNQRTYLWVELGLQTIHQSTSDLINRAHDMKTYYDGVAKLRKHNINVCTHIINGLPGEDYDMMMATAKEVAQMDVQGIKIHLLHLLKGTPMVKQYDKGLLTFMTQEEYTNLVVDQLEVIPPEMIVHRITGDGPIDIMVGPMWSVNKWEVLNGIDAELARRNSYQGLRYKSKVKQ
>NC_002745|1808959:1866661|1860871_1861006_-|WP_001791797.1|DBSCAN-SWA
MHYLICIKANQRLIFTNSIVDWFYLCMNEQLFDIIKNINDFESI
>NC_002745|1808959:1866661|1850939_1851395_-|WP_012840523.1|DBSCAN-SWA
MKICLMLYLLIFLSSCGTNNKIVGQRFEIQQHNETIGSIYFSADYAHIRGIEKGTAKYFIDKVGSKRYLFIEYIPDNVLNCKPDFWKTLKYKKDKVTYYVYLIENLDDEVFHLSALQDMNRIPIDIADDVATMGKSPHQNDRMTLKLNKNN
>NC_002745|1808959:1866661|1826635_1827268_-|WP_000493887.1|DBSCAN-SWA
MFTGIVEEIGVVKSVQIRQSVRTIEIEAHKITADMHIGDSISVNGACLTVIDFDQTSFTVQVIKSTENKTYLADVKRQSEVNLERAMSGNGRFGGHFVLGHVDELGTVSKINETANAKIITIQCSQHINNQLVKQGSITVDGVSLTVFDKHDNSFDIHLIPETRRSTILSSKKLGDKVHLETDVLFKYVENILNKDKDQLSVDKLRAFGF
>NC_002745|1808959:1866661|1854165_1854507_+|WP_000627540.1|DBSCAN-SWA
MITFENIQQLEKYTLMTMHGLFNQLKLGIISIDNAEHTLFTPYMMESLSSLGVKPDIIDLIHKGTELEDFAAFNLSIEDTVTVCLQRTEELLNQYKNVEFNDKILINWRIIQE
>NC_002745|1808959:1866661|1832516_1833371_-|WP_001032833.1|DBSCAN-SWA
MNKHKKGSIFGIIGLVVIFAVVSFLFFSMISDQIFFKHVKSDIKIEKLNVTLNDAAKKQINNYTSQQVSNKKNDAWRDASATEIKSAMDSGTFIDNEKQKYQFLDLSKYQGIDKNRIKRMLVDRPTLLKHTDDFLKAAKDKHVNEVYLISHALLETGAVKSELANGVEIDGKKYYNFYGVGALDKDPIKTGAEYAKKHGWDTPEKAISGGADFIHKHFLSSTDQNTLYSMRWNPKNPGEHQYATDIKWAESNATIIADFYKNMKTEGKYFKYFVYKDDSKHLNK
>NC_002745|1808959:1866661|1843214_1844411_-|WP_000933820.1|DBSCAN-SWA
MLNNKRLFTSESVTEGHPDKIADQVSDAILDAILKDDPNARVACETTVTTGMALIAGEISTTTYVDIPKVVRETIKEIGYTRAKYGYDYETMAILTAIDEQSPDIAQGVDKALEYRDKDSEEEIEATGAGDQGLMFGYATNETETYMPLAIYLSHQLAKRLSDVRKDGTLNYLRPDGKVQVTVEYDENDNPVRIDTIVVSTQHADDVTLEQIQEDIKAHVIYPTVPENLINEQTKFYINPTGRFVIGGPQGDAGLTGRKIIVDTYGGYARHGGGCFSGKDPTKVDRSAAYAARYVAKNIVAAGLADQCEVQLAYAIGVAEPVSIAIDTFGTGKVSEGQLVEAVRKHFDLRPAGIIKMLDLKQPIYKQTAAYGHFGRTDVLFPWEKLDKVEELKDAVKY
>NC_002745|1808959:1866661|1831137_1832430_+|WP_000989121.1|DBSCAN-SWA
MMTTLATLIFLVTLLFVLWQPKGLDIGITALTGAFIAVITGVVSFSDVFEVTGIVWNATLTFVSVILISLILDKVGLFEWSAIHMLHASKGNGLKMFVYIILLGAIVAAFFANDGAALILTPIVLAMVKNIGFSKRAIFPFIIASGFIADTTSLPLIVSNLVNIISADYFHVGFVRYFSRMIIPNLFSLLASIIVLWLYFRKAIPKTFDDNNIKHPKDAINDLKLFKISWIVLVILLFGYLISEFTKIPVSIFTGIIAFIFLMLARKSNAVNIKQVIKGAPWNIVLFSIGMYIVVFGLRNAGITLILAKILEYISNYGLFSTILGMGFISAFLSSIMNNMPTVLIDAIAIGQSNVHGMLKEGLIYANVIGSDLGPKITPIGSLATLLWLHVLTQKDVKISWGTYFKTGIIITIPVLFITLIGLYLTLIIF
>NC_002745|1808959:1866661|1853498_1854125_+|WP_000669024.1|DBSCAN-SWA
MKFKAIVAITLSFSLLTACGANQHKENNSKSNDTTKKTQETDNTTQSNTEKQMTPQEAEDIVRNDYKARGANENQTLNYKTNLERSNEHEYYVEHLVRDAVGTPLKRCAIVNRHNGTIINIFDDMSEKDKEEFEAFKKRSPKYNPGMSDHDKTDGESEDIQHHDNDNNKAIQNDTPDQKAVDKNDKNAVNKEEKHDNHAKNSAETKVK
>NC_002745|1808959:1866661|1808959_1815520_-|WP_001050566.1|DBSCAN-SWA
MNLLKKNKYSIRKYKVGIFSTLIGTVLLLSNPNGAQALTTDNNVQSDTNQATPVNSQDTNVANNRGLANSAQNTPNQSATTNQSTNQALVNHNNGSIANQATPTSVQSSTPSAQNNNHTDGNTTATETVSNANNKDVVSNNTTLNVPNKTNENGSGGHLTLKEIQEDVRHSSDKPELVAIAEQASNRPKKRSRRAAPADPNATPADPAAAAAGNGGAPVAITAPYTPTTDPNANNAGQNAPNEVLSFDDNGIRPSTNRSVPSVTVVDNLPGFTLINGGKVGVFSHAMVRTSMFDSGDAKNYQAQGNVIALGRIKGNDTNDHGDFNGIEKSLTVNPNSELIFEFNTMTTKNYQGVTNLIIKNADNDTVIAEKSVAYGPIWRLFKVPENVSHLKIQFVPKNDAITDARGIYQLRDGYKYYDFVDSIGLHSGSHVYVERRTMEPTATNNKEFTVTTSLKNNGNFGASFNTDDFVYKVQLPEGVEYVNNSLTKDFPSSNSGVDMNDFNVTYDAANRVITIKSTGGGSGNSPARLMPDKILDLKYKLRVNNVPTPRTVTFNDTLTYKTYTQDFINSPAESHTVSTNPYTIDIIMNKDALQAEVDRRIQQADYTFASLDIFNDLKRRAQTILDENRNNVPLNKRVSQADIDSLTNQMQHTLIRSVDAENAVNKKVDQMEDLVNQNDELTDEEKQAAIQVIEEHKNEIIGNIGDQTTDDGVTRIKDQGIQTLSGDTATPVVKPNAKKAIRDKATKQREIINATPDATEDEIQDALNQLATDETDAIDNVTNATTNADVEIAKNNGINTIGAVVPQVTHKQAARDAINQATATKRQQINSNREATQEEKNAALNELTQATNHALEQINQATTNADVDNAKGDGLNAINPIAPVTVVKQAARDAVSHDAQQHIAEINANPDATQEERQAAIDKVNAAVTAANTNILNANTNADVEQVKTNAIQGIQAITPATKVKTDAKNAIDKSAETQHNTIFNNNDATLEEQQAAQQLLDQAVATAKQNINAADTNQEVAQAKDQGTQNIVVIQPATQVKTDARNAVNDKAREAITNINATPGATREEKQEAINRVNTLKNRALTDIGVTSTTAMVNSIRDDAVNQIGAVQPHVTKKQTATGVLNDLATAKKQEINQNTNATTEEKQVALNQVDQELATAINNINQADTNAEVDQAQQLGTKAINAIQPNIVKKPAALAQINQHYNAKLAEINATPDATNDEKNAAINTLNQDRQQAIESIKQANTNAEVDQAATVAENNIDAVQVDVVKKQAARDKITAEVAKRIEAVKQTPNATDEEKQAAVNQINQLKDQAINQINQNQTNDQVDTTTNQAVNAIDNVEAEVVIKPKAIADIEKAVKEKQQQIDNSLDSTDNEKEVASQALAKEKEKALAAIDQAQTNSQVNQAATNGVSAIKIIQPETKVKPAAREKINQKANELRAKINQDKEATAEERQVALDKINEFVNQAMTDITNNRTNQQVDDTTSQALDSIALVAPEHIVRAAARDAVKQQYEAKKQEIEQAEHATDEEKQVALNQLANNEKLALQNINQAVTNNDVKRVETNGIATLKGVQPHIVIKPEAQQAIKATAENQVESIKDTPHATVDELDEANQLISDTLKQAQQEIENTNQDAAVTDVRNQTIKAIEQIKPKVRRKRAALDSIEENNKNQLDAIRNTLDTTQDERDVAIDTLNKIVNTIKNDIAQNKTNAEVDRTETDGNDNIKVILPKVQVKPAARQSVGVKAEAQNALIDQSDLSTEEERLAAKHLVEQALNQAIDQINHADKTAQVNQDSIDAQNIISKIKPATTVKATALQQIQNIATNKINLIKANNEATDEEQNIAIAQVEKELIKAKQQIASAVTNADVAYLLHDEKNEIREIEPVINRKASAREQLTTLFNDKKQAIEANIQATVEERNSILAQLQNIYDTAIGQIDQDRSNAQVDKTASLNLQTIHDLDVHPIKKPDAEKTINDDLARVTALVQNYRKVSNRNKADALKAITALKLQMDEELKTARTNADVDAVLKRFNVALSDIEAVITEKENSLLRIDNIAQQTYAKFKAIATPEQLAKVKVLIDQYVADGNRMIDEDATLNDIKQHTQFIVDEILAIKLPAEATKVSPKEIQPAPKVCTPIKKEETHESRKVEKELPNTGSEGMDLPLKEFALITGAALLARRRTKNEKES
>NC_002745|1808959:1866661|1844782_1846375_+|WP_000109906.1|DBSCAN-SWA
MSVDTYTETTKIDKLLKKPTSHFQLSTTQLYNKILDNNEGVLTELGAVNASTGKYTGRSPKDKFFVSEPSYRDNIDWGEINQPIDEETFLKLYHKVLDYLDKKDELYVFKGYAGSDKDTMLKLTVINELAWHNLFAKNMFIRPESKEEATKIKPNFTIVSAPHFKADPEVDGTKSETFVIISFKHKVILIGGTEYAGEMKKGIFSVMNYLLPMQDIMSMHCSANVGEKGDVALFFGLSGTGKTTLSADPHRKLIGDDEHGWNKNGVFNIEGGCYAKAINLSKEKEPQIFDAIKYGAILENTVVAEDGSVDFEDNRYTENTRAAYPINHIDNIVVPSKAAHPNTIIFLTADAFGVIPPISKLNKDQAMYHFLSGFTSKLAGTERGVTEPEPSFSTCFGAPFFPLHPTVYADLLGELIDLHDVDVYLVNTGWTGGKYGVGRRISLHYTRQMVNQAISGKLKNAEYTKDSTFGLSIPVEIEDVPKTILNPINAWSDKEKYKAQAEDLIQRFEKNFEKFGEKVEHIAEKGSFNK
>NC_002745|1808959:1866661|1856752_1856854_+|WP_001792025.1|DBSCAN-SWA
MQGFKEKHQELKKALCQIGLMSSISEVRQLNIA
>NC_002745|1808959:1866661|1847503_1847977_-|WP_000672013.1|DBSCAN-SWA
MKFRDKDNRQVNLTFKKDNEIADGNHVLAIPTFKNQLLFTKHNLRGIEFPGGKRERGESSAEAVTRELYEETGAKVKNIHYIAQYTIETHDQTDFVKDVYFIEVESLVSKNDYLETAGPVLFNCINDIELAQRSFLLQDSTILKCVERVQSLGFYQT
>NC_002745|1808959:1866661|1816178_1818596_-|WP_001557386.1|tRNA|DBSCAN-SWA
MLNYNHNQIEKKWQDYWDENKTFKTNDNLGQKKFYALDMFPYPSGAGLHVGHPEGYTATDIISRYKRMQGYNVLHPMGWDAFGLPAEQYALDTGNDPREFTKKNIQTFKRQIKELGFSYDWDREVNTTDPEYYKWTQWIFIQLYNKGLAYVDEVAVNWCPALGTVLSNEEVIDGVSERGGHPVYRKPMKQWVLKITEYADQLLADLDDLDWPESLKDMQRNWIGRSEGAKVSFDVDNTEGKVEVFTTRPDTIYGASFLVLSPEHALVNSITTDEYKEKVKAYQTEASKKSDLERTDLAKDKSGVFTGAYAINPLSGEKVQIWIADYVLSTYGTGAIMAVPAHDDRDYEFAKKFDLPIIEVIEGGNVEEAAYTGEGKHINSGELDGLENEAAITKAIQLLEQKGAGEKKVNYKLRDWLFSRQRYWGEPIPVIHWEDGTMTTVPEEELPLLLPETDEIKPSGTGESPLANIDSFVNVVDEKTGMKGRRETNTMPQWAGSCWYYLRYIDPKNENMLADPEKLKHWLPVDLYIGGVEHAVLHLLYARFWHKVLYDLGIVPTKEPFQKLFNQGMILGEGNEKMSKSKGNVINPDDIVQSHGADTLRLYEMFMGPLDAAIAWSEKGLDGSRRFLDRVWRLMVNEDGTLSSKIVTTNNKSLDKVYNQTVKKVTEDFETLGFNTAISQLMVFINECYKVDEVYKPYIEGFVKMLAPIAPHIGEELWSKLGHEESITYQPWPTYDEALLVDDEVEIVVQVNGKLRAKIKIAKDTSKEEMQEIALSNDNVKASIEGKDIMKVIAVPQKLVNIVAK
>NC_002745|1808959:1866661|1859151_1860708_-|WP_000028669.1|DBSCAN-SWA
MSITEKQRQQQAELHKKLWSIANDLRGNMDASEFRNYILGLIFYRFLSEKAEQEYADALSGEDITYQEAWADEEYREDLKAELIDQVGYFIEPQDLFSAMIREIETQDFDIEHLATAIRKVETSTLGEESENDFIGLFSDMDLSSTRLGNNVKERTALISKVMVNLDDLPFVHSDMEIDMLGDAYEFLIGRFAATAGKKAGEFYTPQQVSKILAKIVTDGKDKLRHVYDPTCGSGSLLLRVGKETQVYRYFGQERNNTTYNLARMNMLLHDVRYENFEIRNDDTLENPAFLGNTFDAVIANPPYSAKWTADSKFENDERFSGYGKLAPKSKADFAFIQHMVHYLDDEGTMAVVLPHGVLFRGAAEGVIRRYLIEEKNYLEAVIGLPANIFYGTSIPTCILVFKKCRQQDDNVLFIDASNDFEKGKNQNHLSDAQVERIIDTYKRKATIDKYSYSATLQEIADNDYNLNIPRYVDTFEEEAPIDLDQVQQDLKNIDKEIAEIEQEINAYLKELGVLKDE
>NC_002745|1808959:1866661|1828798_1830301_-|WP_001261668.1|DBSCAN-SWA
MRVAIIGMGTAGVSVLRELVKHPKFNQLDIDLYDDKVNMGQGVPFQNDSSELLINMPSKKMSLNLDDETEFWKWYKQQTDFNFDEPAYLPRFVFGHYMKSYLSMFTKKYPNISTNYNKVQEIYTNSNIDETNLTYYICTTNSEQSWQAYDYVFLTCGTFAYHDPYNLKGKKGYIATPYPTYNTLDEVNELDDIAIIGTGLASLDVVRYVAAHHPKLPITMTSRSAHLPSVRGTMIDVTFKYLTKDKLNDIKKHHFGNAPLDTIVSLFLKECAEYDIDFKKLVHRRTGNHIADLKYDLARPTEMGIFQSMIEHLKENLNWIWNSLSIEDQHQFNQKYSKMIQLNSNPMPPRTAELIIELIENKSLILKKDLEDVKHDGKLYYFSYKNQESVDMYNVVINATGAKSHLNELDQDDQLIKNLENRQIVQAHPMGGIQIIPETNQVISPRFGTLTNMIAIGQMTNGVNKLRNGVKMIVEQVAHTVSQLYDALESNEQQQRSYNQ
>NC_002745|1808959:1866661|1834652_1835096_+|WP_001153742.1|DBSCAN-SWA
MQDNSTKYLLYIQTATSNHLETNCVFLHCDYILKVPINKLVSYYAKLHLSSQSVLIETAKNILNINKLVPIYINPKTILFPLKHKRAPIQIYINAHYIVGMTAIENSTLIHFQEGIQLEVDEPFSLVSKKCHESLALKHFIENTISN
>NC_002745|1808959:1866661|1863562_1864285_-|WP_001039454.1|protease|DBSCAN-SWA
MNKNVVIKSLATLTILTSVTGIGTTLVEEVQQTAKAENNVTKIQDTNIFPYTGVVAFKSATGFVVGKNTILTNKHVSKNYKVGDRITAHPNSDKGNGGIYSIKKIINYPGKEDVSVIQVEERAIERGPKGFNFNDNVTPFKYAAGAKAGERIKVIGYPHPYKNKYVLYESTGPVMSVEGSSIVYSAHTESGNSGSPVLNSNNELVGIHFASDVKNDDNRNAYGVYFTPEIKKFIAENIDK
>NC_002745|1808959:1866661|1836896_1837610_-|WP_001096495.1|DBSCAN-SWA
MAKLNVEVFADGADIEEMKAAYKNKQVDGFTTNPSLMAKAGVTDYKAFAEEAVKEIPDASISFEVFADDLETMEKEAAILKQYGENVFVKIPIVNTKGESTIPLIKKLSADNVRLNVTAVYTIEQVKEITEAVTEGVPTYVSVFAGRIADTGVDPLPLMKEAVKVTHSKDGVKLLWASCRELFNVIQADEIGADIITRPADVVKKVNTNLGRDINELSVDTVKGFAKDIQSSGLSIL
>NC_002745|1808959:1866661|1815845_1816157_-|WP_000836461.1|DBSCAN-SWA
MKSITTDELKNKLFESKPVQIVDVRTDEETAMGYIPNAKLIPMDTIPDNLNSFNKNEIYYIVCAGGVRSAKVVEYLEANGIDAVNVEGGMHAWGDEGLEIKSI
>NC_002745|1808959:1866661|1823612_1823732_-|WP_001790712.1|DBSCAN-SWA
MMLISFIYNNMDNNNTINRNLHSEFAIIMLLKINEKGAV
>NC_002745|1808959:1866661|1856534_1856630_+|WP_001801861.1|DBSCAN-SWA
MMLIFVHIIAPVISGCAIAFFSYWLSRRNTK
>NC_002745|1808959:1866661|1852428_1853424_+|WP_000070642.1|DBSCAN-SWA
MSNQFKSEEERRQWEQFQAFQNQQNQQHQQYGQKKSKKGWFWGCGGCLVLFILIIIGISACTAGVTGNLGGNSSKEANKTHKIGETVKNGDLEVTVNSVETMKSVGPSLAPTNAKGIFVVADVTIKNKGKEALTIDSSMFKLKSGDKTFEADNTGSMSANQSDNGSIENSFFLQRINPDSTAQGKIVFDVSENIANAKDKKLEVISSLFSVKKITFDLSDAKKTSKAKKDKQDTEVAVASSNSDNVNYEASATTPATTSSADTDSEDSEKSSKDEDKQNASKSDKSSVEKSESNEETATVEPMPQSKPTTSEAPPSQNNHNENNMYDASTE
>NC_002745|1808959:1866661|1864409_1865117_-|WP_001039427.1|protease|DBSCAN-SWA
MNKNVMVKGLTALTILTSLGFAENISNQPHSIAKAEKNVKEITDATKAPYNSVVAFAGGTGVVVGKNTIVTNKHIAKSNDIFKNRVAAHYSSKGKGGGNYDVKDIVEYPGKEDLAIVHVHETSTEGLNFNKNVSYTKFAEGAKAKDRISVIGYPKGAQTKYKMFESTGTINHISGTFIEFDAYAQPGNSGSPVLNSKHELIGILYAGSGKDESEKNFGVYFTPQLKEFIQNNIEK
>NC_002745|1808959:1866661|1834069_1834540_+|WP_000671057.1|DBSCAN-SWA
MKFNDVYNKHHKIIHHLLKKYNISYNYDEYYQLLLIKMWQLSQIYKPSSKQSLSSFLFTRLNYYLIDLFRQQNQLKDVILCENNSPTLTEQPTYFNEHDLRLQDIFKLLNHRERLWLKLYLEGYKQFEIAEIMSLSLSTIKLIKMSVKRKCQHNFN
>NC_002745|1808959:1866661|1838789_1839143_+|WP_000623470.1|DBSCAN-SWA
MISIILVMIGGGFGAIARSAITDYFNHKFTSKLPIATLIVNLVGSFLIGLTIGLSISISWFPAFFVTGFLGGLTTFSTLAKELTLMMTPKFDINLFLNYSLLQFIIGFIACYIGYHI
>NC_002745|1808959:1866661|1822782_1823610_-|WP_000266096.1|DBSCAN-SWA
MWKWEAENDAKGVVVIAHNILEHTGRYAYVITMLRRNGYHVIMGDLPGQGQTSRANKGQIENFQTYHESLLDWLKIANEYKIPTYVLGVGLGGLILLNLLEKVELPIEGMMLISPMLELQKNGKNRKDKLVSNIGKISKDTRFNVGVEPKDLTRNLEIVEETVNDGLMLKKATYHWYNTINETMKDTMAHIHDIQPMPTLLMYGTKDLIVDTRAIDEFKEKYQTPELYFKAWQGFYHEVHNEPERDEVMRYILTFLNNSVNTMGFIVEDDEIVEI
>NC_002745|1808959:1866661|1848042_1848300_+|WP_000718107.1|DBSCAN-SWA
MKKIFLAMIHFYQRFISPLTPPTCRFYPTCSEYTREAIQYHGAFKGLYLGIRRILKCHPLHKGGFDPVPLKKDKSASKHSHKHNH
>NC_002745|1808959:1866661|1823843_1824845_+|WP_001196362.1|DBSCAN-SWA
MALLKNFFIGLSNNSFLNNAAKKVGPRLGANKVVAGNTIPELINTIEYLNDKNIAVTVDNLGEFVGTVEESNHAKEQILTIMDALHQHGVKAHMSVKLSQLGAEFDLELAYQNLREILLKANTYNNMHINIDTEKYASLQQIVQVLDRLKGEFRNVGTVIQAYLYDSHKLVDKYQDLRLRLVKGAYKENESIAFQSKEDVDANYIKIIEQRLLNARNFTSIATHDHRIINHVKQFMKENHIEKDRMEFQMLYGFRSELAEEIANEGYNFTIYVPYGDDWFAYFMRRLAERPQNLSLAVKEFVKPAGLKRVGIIAALGATVMLGLSTIKKLCRK
>NC_002745|1808959:1866661|1837869_1838172_+|WP_000091442.1|DBSCAN-SWA
MSRSKKYFYLSSLMIILSFFFNTNNVFLSGFFNSFIKLILFCSVINSIVLILSIIFADRSIKSLKPDADWIRIASKSLPWIILIVILVHIFSIVRTFGFI
>NC_002745|1808959:1866661|1835082_1835526_-|WP_001030469.1|DBSCAN-SWA
MNKASFDKKVKKQLWFLNKKEKQALDQRLSSISDDDSVNLNKPVTFANAYLRQNVFRNKETKSYSMFVTLVVMMFAYVALLGLFLFGLITSLSGVQFFVSPKVDLSTTVVILTIIGAILLMIVSIYFIKIVTSYFTKKLLEIKFNSK
>NC_002745|1808959:1866661|1854607_1855180_+|WP_000414216.1|DBSCAN-SWA
MEKNEYTAKYNEYSQLLDATYSQAVAYLLNKYGAVTDDYYKEKSYTRFLNGEIKSISKGKYTRASEGLYCHHISEDKFQNLSDLRFISEFKYSYNVQKKENLVYCDLIEHLILHAIITKESNGQFGVAGLCQMIKPTVIDWYISEYTPKPAWMQATKARAYLPRILVEKLLIKIDDMLEGIEIYDFLESR
>NC_002745|1808959:1866661|1849302_1850781_-|WP_000348364.1|DBSCAN-SWA
MDFWLYKQAQQNGHHIAITDGQESYTYQNLYCEASLLAKRLKAYQQSRVGLYIDNSIQSIILIHACWLANIEIAMINTRLTPNEMTNQMRSIDVQLIFCTLPLELRGFQIVSLDDIEFAGRDITTNGLLDNTMGIQYDTSNETVVPKESPSNILNTSFNLDDIASIMFTSGTTGPQKAVPQTFRNHYASAIGCKESLGFDRDTNWLSVLPIYHISGLSVLLRAVIEGFTVRIVDKFNAEQILTMIKNERITHISLVPQTLNWLMQQGLHEPYNLQKILLGGAKLSATMIETALQYNLPIYNSFGMTETCSQFLTATPEMLHARPDTVGMPSANVDVKIKNPNKEGHGELMIKGANVMNGYLYPTDLTGTFENGYFNTGDIAEIDHEGYVMIYDRRKDLIISGGENIYPYQIETVAKQFPGISDAVCVGHPDDTWGQVPKLYFVSESDISKAQLIAYLSKHLAKYKVPKHFEKVDTLPYTSTGKLQRNKLYRG
>NC_002745|1808959:1866661|1835821_1836457_+|WP_001168903.1|protease|DBSCAN-SWA
MQKFKDFFYDDLSVTRGNYFLTLMAAFFITIILFIGIVVSEVHLLYSMLIVLVGLILLRLFKINLFSFKKLTLSQVIYIIGGALLIYGLDNLYLYFHDVPANELQLEQEIRNTPFYISIFTVTIIPAIVEEIVFRGMIIRVIFRKHLFLGLLVSSLVFASLHESDTWIGYLPYLYSGLIFGLIYIKTKRLEVVIFMHFLNNLLALLFIIWG
>NC_002745|1808959:1866661|1830823_1831138_+|WP_000221177.1|DBSCAN-SWA
MTYKELATFLKVLSDSSRLEILDLLSCGELCACDLLAHFQFSQPTLSYHLKALVKTNLVTTRKIGNKHLYQLNHNIFESVINNLSKVHTSNQRCFCHNLKTGEC
>NC_002745|1808959:1866661|1866079_1866661_+|WP_001092780.1|DBSCAN-SWA
MNTKFLGKTLVASALVLTTLGTGLHSSYLGLNTNKVVKTAKAEEKMTNGQLWKKVKDSLIDSNIISGNENEEITVTYVNKTGYSSSVSAYGNNNDDFSSTPSNFSKLKEIDLKKDNVPSDDFNTTVSGEDSWKTLTSKLKEKGLVTDGQTVTIHCNDKSDNTKSSVSGKVGADLTSGNGTTFKKRFIDKITID
>NC_002745|1808959:1866661|1818883_1820065_-|WP_001025067.1|DBSCAN-SWA
MNIPKSVWWLVIGMALNITGSSFLWPLNTIYMKQELGKSLTVAGLVLMINSFGMVIGNLLGGSLFDKLGGYKTILIGTFTCLCSTTLLNFFHGWPWYAVWLVMLGFGGGMIIPAIYAMAGAVWPNGGRQTFNAIYLAQNIGVAVGAAMGGFVAEFSFNYIFLANLIMYVVFALVAVTQFNIEINAKVKYPTHLDITGKKNKARFISLVLICAMFAICWVAYIQWESTIASFTQSINISMAQYSVLWTINGIMILVAQPLIKPVLYLLKGNLKKQMFVGIIIFMLSFFVTSFAENFTIFVVGMIILTFGEMFVWPAVPTIANQLAPDGKQGQYQGFVNSAATVGKAFGPFLGGVLVDAFNMRMMFIGMMLLLVFALILLMVFKENNTQPKKIDA
>NC_002745|1808959:1866661|1842184_1843093_-|WP_000366163.1|DBSCAN-SWA
MDLSSPVVIGLIIAVVIALIFFVLFLVALGSKKKVKRQTEEKYEQQEQNIKKSHEEALEKERIQNKKTITKQQEDYNHMVSTKDREIDALKLFSKNHSEYVTDMRLIGIRERLVKEKRIRPEDMHIMANIFLPKDGFNNIERISHLVLTRTGLYIIDSQLLKGHVYNGISGGQFKDLPPMEQVFDTLDLDKSRPQTIVMDQNDDKRSLSFVNYSDQIEAIKQLAEDLQKELGAKYTPTSILYFNPKNEGDVTISNYNQNSAVKVLVGAEQLDEFFNKFVFHGRIQYNVEDLQQMMDKIESFN
>NC_002745|1808959:1866661|1825443_1826625_-|WP_001159037.1|DBSCAN-SWA
MQFDNIDSALMALKNGETIIVVDDENRENEGDLVAVTEWMNDNTINFMAKEARGLICAPVSKDIAQRLDLVQMVDDNSDIFGTQFTVSIDHVDTTTGISAYERTLTAKKLIDPSSEAKDFNRPGHLFPLVAQDKGVLARNGHTEAAVDLAKLTGAKPAGVICEIMNDDGTMAKGQDLQNFKEKHQLKMITIDDLIEYRKKLEPEIEFKAKVKMPTDFGTFDMYGFKATYTDEEIVVLTKGAIRQHENVRLHSACLTGDIFHSQRCDCGAQLESSMKYINEHGGMIIYLPQEGRGIGLLNKLRAYELIEQGYDTVTANLALGFDEDLRDYHIAAQILKYFNIEHINLLSNNPSKFEGLKQYGIDIAERIEVIVPETVHNHDYMVTKKIKMGHLI
>NC_002745|1808959:1866661|1846752_1847499_-|WP_001822900.1|DBSCAN-SWA
MPIESFTHQFEEITYLSDDLQVKALMMTPHHEVNRIVVYLRGGKGQVGRVRAGRLMQFSDSQTLVIGPYYRGNNGSEGKDEFYRGDLNDVTQLLRLLHDKYPHAFIHMVGFSRGGLQGLLTFQDLPVTSYTIWGGVSDIDLMYEERVDLRGMLRRMIGHPKKDRAAYEARQAIPNINENSPPILIVHGGKDQQVGIHHAYYLADQLELKGATHETFYQMAEGHVPRPPAMVETLTYIKEFMKQVELHS
>NC_002745|1808959:1866661|1861945_1862665_-|WP_001038704.1|protease|DBSCAN-SWA
MNKNIIIKSIAALTILTSITGVGTTVVDGIQQTAKAENSVKLITNTNVAPYSGVTWMGAGTGFVVGNHTIITNKHVTYHMKVGDEIKAHPNGFYNNGGGLYKVTKIVDYPGKEDIAVVQVEEKSTQPKGRKFKDFTSKFNIASEAKENEPISVIGYPNPNGNKLQMYESTGKVLSVNGNIVTSDAVVQPGSSGSPILNSKREAIGVMYASDKPTGESTRSFAVYFSPEIKKFIADNLDK
>NC_002745|1808959:1866661|1824966_1825431_-|WP_001008549.1|DBSCAN-SWA
MNFEGKLIGKDLKVAIVVSRFNDFITGRLLEGAKDTLIRHDVNEDNIDVAFVPGAFEIPLVAKKLASSGNYDAIITLGCVIRGATSHYDYVCNEVAKGVSKVNDQTNVPVIFGILTTESIEQAVERAGTKAGNKGAEAAVSAIEMANLLKSIKA
>NC_002745|1808959:1866661|1862785_1863505_-|WP_001038872.1|protease|DBSCAN-SWA
MNKNIVIKSMAALAILTSVTGINAAVVEETQQIANAEKNVTQVKDTNNFPYNGVVSFKDATGFVIGKNTIITNKHVSKDYKVGDRITAHPNGDKGNGGIYKIKSISDYPGDEDISVMNIEEQAVERGPKGFNFNENVQAFNFAKDAKVDDKIKVIGYPLPAQNSFKQFESTGTIKRIKDNILNFDAYIEPGNSGSPVLNSNNEVIGVVYGGIGKIGSEYNGAVYFTPQIKDFIQKHIEQ
>NC_002745|1808959:1866661|1848296_1849298_-|WP_000778528.1|DBSCAN-SWA
MKLTALHFYKYSEPFKSQIVTPKVTLTHRDCLFIELIDDKGNAYFGECNAFQTDWYDHETIASVKHVIEQWFEDNRNKSFETYEAALKLVDSLENTPAARATIVMALYQMFHVLPSFSVAYGATASGLSNKQLESLKATKPTRIKLKWTPQIMHQIRVLRELDFHFQLVIDANESLDRQDFTQLQLLAREQVLYIEEPFKDISMLDEVVDGTIPPIALDEKATSLLDIINLIELYNVKVVVLKPFRLGGIDKVQTAIDTLKSHGVKVVIGGMYEYGLSRYFTAMLARKGDYPGDVTPAGYYFDQDVVTKSGILKEGRLEFRPPLVDITQLQPY
>NC_002745|1808959:1866661|1861889_1861997_+|WP_011447030.1|DBSCAN-SWA
MLILLLISKNHLSMYGWMIYLSKLSAINFLISGEK
>NC_002745|1808959:1866661|1838427_1838793_+|WP_001200542.1|DBSCAN-SWA
MQYVYIFIGGALGALLRYLISFLNTDGGFPIGTLIANLTGAFVMGLLTALTIAFFSNHPTLKKAITTGFLGALTTFSTFQLELIHMFDHQQFITLLLYAVTSYVFGILLCYVGIKLGGGLS
>NC_002745|1808959:1866661|1861068_1861788_-|WP_001038752.1|protease|DBSCAN-SWA
MNKNIIIKSIAALTILTSVTGVGTTMVEGIQQTAKAENTVKQITNTNVAPYSGVTWMGAGTGFVVGNHTIITNKHVTYHMKVGDEIKAHPNGFYNNGGGLYKVTKIVDYPGKEDIAVVQVEEKSTQPKGRKFKDFTSKFNIASEAKENEPISVIGYPNPNGNKLQMYESTGKVLSVNGNIVSSDAIIQPGSSGSPILNSKHEAIGVIYAGNKPSGESTRGFAVYFSPEIKKFIADNLDK

Homologous phage analysis in the prophage region

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_001050566.1|1808959_1815520_-	LPXTG-anchored repetitive surface protein SasC	A0A2H4PQU6	Staphylococcus_phage	6.1e-306	98.3
WP_000836461.1|1815845_1816157_-	rhodanese-like domain-containing protein	A0A2H4PQR9	Staphylococcus_phage	4.8e-52	99.0
WP_001557386.1|1816178_1818596_-|tRNA	leucine--tRNA ligase	A0A2H4PQS0	Staphylococcus_phage	0.0e+00	99.5
WP_001025067.1|1818883_1820065_-	MFS transporter	A0A2H4PQR6	Staphylococcus_phage	7.3e-218	99.7
WP_000526539.1|1820174_1821128_+	TIGR01212 family radical SAM protein	A0A2H4PQV5	Staphylococcus_phage	2.2e-79	100.0
WP_000764419.1|1821124_1821688_+	class I SAM-dependent methyltransferase	A0A2H4PQV0	Staphylococcus_phage	8.3e-103	99.5
WP_000757543.1|1821810_1822212_-	MarR family transcriptional regulator	NA	NA	NA	NA
WP_000266096.1|1822782_1823610_-	alpha/beta hydrolase	NA	NA	NA	NA
WP_001790712.1|1823612_1823732_-	hypothetical protein	NA	NA	NA	NA
WP_001196362.1|1823843_1824845_+	proline dehydrogenase	A0A2H4PQT6	Staphylococcus_phage	2.6e-184	99.4
WP_001008549.1|1824966_1825431_-	6,7-dimethyl-8-ribityllumazine synthase	A0A2H4PQS3	Staphylococcus_phage	4.5e-70	100.0
WP_001159037.1|1825443_1826625_-	3,4-dihydroxy-2-butanone-4-phosphate synthase	A0A2H4PQS2	Staphylococcus_phage	5.6e-226	99.5
WP_000493887.1|1826635_1827268_-	riboflavin synthase	A0A2H4PQS5	Staphylococcus_phage	5.5e-111	98.6
WP_000077358.1|1827274_1828318_-	bifunctional diaminohydroxyphosphoribosylaminopyrimidine deaminase/5-amino-6-(5-phosphoribosylamino)uracil reductase RibD	A0A2H4PQS8	Staphylococcus_phage	5.3e-196	98.8
WP_001261668.1|1828798_1830301_-	FAD/NAD(P)-binding protein	A0A2H4PQX2	Staphylococcus_phage	1.9e-29	98.6
WP_000221177.1|1830823_1831138_+	winged helix-turn-helix transcriptional regulator	A0A2H4PQT4	Staphylococcus_phage	9.8e-53	98.1
WP_000989121.1|1831137_1832430_+	arsenite efflux transporter membrane subunit ArsB	A0A2H4PQU3	Staphylococcus_phage	5.0e-228	99.5
WP_001032833.1|1832516_1833371_-	glucosaminidase domain-containing protein	Q4ZCC7	Staphylococcus_virus	9.8e-39	38.6
WP_000384171.1|1833646_1833871_-	hypothetical protein	NA	NA	NA	NA
WP_000671057.1|1834069_1834540_+	RNA polymerase sigma factor	A0A2H4PQT5	Staphylococcus_phage	8.8e-82	98.1
WP_001153742.1|1834652_1835096_+	competence protein ComK	NA	NA	NA	NA
WP_001030469.1|1835082_1835526_-	hypothetical protein	A0A2H4PQT8	Staphylococcus_phage	2.4e-57	98.6
WP_001168903.1|1835821_1836457_+|protease	CPBP family intramembrane metalloprotease SdpA	NA	NA	NA	NA
WP_001096495.1|1836896_1837610_-	transaldolase	M1PR54	Cyanophage	9.4e-19	35.3
WP_000091442.1|1837869_1838172_+	hypothetical protein	NA	NA	NA	NA
WP_001200542.1|1838427_1838793_+	fluoride efflux transporter CrcB	A0A2H4PQR0	Staphylococcus_phage	3.6e-59	100.0
WP_000623470.1|1838789_1839143_+	CrcB family protein	A0A2H4PQQ7	Staphylococcus_phage	3.8e-21	94.0
WP_000453306.1|1841139_1841973_-	aldo/keto reductase	A0A2H4PQR8	Staphylococcus_phage	7.8e-158	99.3
WP_000366163.1|1842184_1843093_-	NERD domain-containing protein	A0A2H4PQQ8	Staphylococcus_phage	3.4e-138	100.0
WP_000933820.1|1843214_1844411_-	methionine adenosyltransferase	A0A2H4PQS6	Staphylococcus_phage	4.3e-218	99.5
WP_000109906.1|1844782_1846375_+	phosphoenolpyruvate carboxykinase (ATP)	A0A2H4PQN1	Staphylococcus_phage	0.0e+00	100.0
WP_001822900.1|1846752_1847499_-	S9 family peptidase	A0A2H4PQM6	Staphylococcus_phage	1.4e-142	98.8
WP_000672013.1|1847503_1847977_-	nucleoside triphosphatase YtkD	A0A2H4PQM4	Staphylococcus_phage	7.2e-84	98.7
WP_000718107.1|1848042_1848300_+	membrane protein insertion efficiency factor YidD	A0A2H4PQM5	Staphylococcus_phage	7.2e-46	100.0
WP_000778528.1|1848296_1849298_-	o-succinylbenzoate synthase	A0A2H4PQM0	Staphylococcus_phage	5.3e-185	97.3
WP_000348364.1|1849302_1850781_-	o-succinylbenzoate--CoA ligase	A0A2H4PQM9	Staphylococcus_phage	2.8e-283	97.6
WP_012840523.1|1850939_1851395_-	DUF4909 domain-containing protein	A0A2H4PQN7	Staphylococcus_phage	3.6e-80	99.3
WP_001795210.1|1851697_1852348_+	excalibur calcium-binding domain-containing protein	A0A2H4PQM8	Staphylococcus_phage	2.9e-51	94.0
WP_000070642.1|1852428_1853424_+	DUF4352 domain-containing protein	A0A2H4PQN2	Staphylococcus_phage	2.6e-67	97.9
WP_000669024.1|1853498_1854125_+	hypothetical protein	A0A2H4PQM7	Staphylococcus_phage	3.1e-74	79.8
WP_000627540.1|1854165_1854507_+	DUF3969 family protein	A0A2H4PQN6	Staphylococcus_phage	1.1e-54	94.7
WP_000414216.1|1854607_1855180_+	hypothetical protein	A0A2H4PQN4	Staphylococcus_phage	2.3e-23	93.1
WP_001801861.1|1856534_1856630_+	type I toxin-antitoxin system Fst family toxin PepA1	NA	NA	NA	NA
WP_001792025.1|1856752_1856854_+	hypothetical protein	NA	NA	NA	NA
WP_000072627.1|1857929_1859159_-	restriction endonuclease subunit S	A0A2H4PQP5	Staphylococcus_phage	4.0e-134	64.7
WP_000028669.1|1859151_1860708_-	type I restriction-modification system subunit M	A0A2H4PQP4	Staphylococcus_phage	1.6e-289	100.0
WP_001791797.1|1860871_1861006_-	hypothetical protein	NA	NA	NA	NA
WP_001038752.1|1861068_1861788_-|protease	serine protease SplF	A0A2H4PQP1	Staphylococcus_phage	1.9e-131	99.6
WP_011447030.1|1861889_1861997_+	hypothetical protein	NA	NA	NA	NA
WP_001038704.1|1861945_1862665_-|protease	serine protease SplD	A0A2H4PQP9	Staphylococcus_phage	4.6e-130	99.6
WP_001038872.1|1862785_1863505_-|protease	serine protease SplC	A0A2H4PQP7	Staphylococcus_phage	1.3e-129	98.7
WP_001039454.1|1863562_1864285_-|protease	serine protease SplB	A0A2H4PQN0	Staphylococcus_phage	3.5e-130	98.3
WP_001039427.1|1864409_1865117_-|protease	serine protease SplA	A0A2H4PQN3	Staphylococcus_phage	7.9e-127	97.0
WP_001092780.1|1866079_1866661_+	DUF4888 domain-containing protein	A0A2H4PQH6	Staphylococcus_phage	9.6e-54	64.8

Sequences of DBSCAN-SWA_5

Nucleotide sequences of DBSCAN-SWA_5

>NC_002745|1976120:2074317|DBSCAN-SWA
TATGAAAAGAAACTTTCCAAAATTAATAGCTTTAAGTTTAATATTTTCTTTAAGTGTTACCCCTATTGCAAACGCTGAGAGCAATTCAAATATCAAAGCAAAAGATAAGAAGCATGTGCAAGTTAATGTCGAGGACAAGAGTGTTCCTACTGACGTACGTAATTTAGCGCAAAAAGACTATCTTTCTTATGTTACTTCACTTGATAAAATCTATAATAAAGAGAAAGCCTCGTATACACTTGGTGAACCTTTTAAAATTTATAAATTCAACAAAAAGAGTGATGGTAATTATTATTTTCCAGTTTTGAACACTGAAGGTAATATCGATTATATAGTTACAATTTCACCAAAAATCACTAAGTATTCTAGTTCATCTTCTAAATACACAATCAATGTTTCTCCATTTTTATCTAAAGTCTTAAATCAATATAAAGATCAACAAATTACTATTTTGACAAACTCAAAAGGTTACTATGTGGTTACTCAAAATCATAAAGCTAAACTAGTACTAAAAACACCACGTCTAGAAGATAAAAAGTTAAAAAAGACTGAGAGTATACCTACTGGCAATAATGTAACGCAACTAAAGCAAAAAGCTTCTGTCACTATGCCAACTAGTCAATTTAAAAGTAATAATTATACTTACAACGAGCAATATATAAATAAACTTGAGAATTTCAAGATAAGAGAAACTCAAGGTAACAATGGTTGGTGTGCAGGCTATACGATGTCTGCATTACTAAATGCGACTTATAATACTAACAAATATCATGCAGAAGCTGTGATGAGATTTTTACACCCAAACTTACAAGGACAACGATTCCAATTTACTGGTTTAACGCCAAGAGAGATGATTTATTTTGGACAAACTCAGGGAAGAAGTCCACAACTTCTTAATAGAATGACTACATATAATGAAGTTGACAATCTTACTAAAAATAATAAAGGAATTGCTGTTTTAGGTAGTAGAGTAGAATCAAGAAATGGTATGCACGCAGGGCATGCCATGGCAGTTGTTGGGAACGCTAAATTAGATAATGGACAAGAGGTTATAATTATATGGAATCCATGGGATAATGGTTTTATGACTCAAGATGCTAAAAACAATGTTATTCCAGTATCCAATGGCGACCATTATCGATGGTATTCATCTATTTATGGTTATTAAAATTTGTATTTTAGAAAGGTAAATAATATTATGGAACAAATTGAATTATTTAGTATTGATAAATTCAAATGTAATTCAGAGGCTAAGTATTATCTTAATATTATTGAGGGAGAATGGCATCCTCAAGATTTAAATGATAGTCCTTTAAAATTTATTCTCAGTACCTCAGACGATTCTGATTACATTTGCAAATATATAAATACAGAACACAAACAACTCACATTATATAATAAAAATAATAGCTCAATTGTTATTGAAATATTTATACCAAATGATAATAAAATACTACTAACAATTATGAACACAGAAGCTTTGGGAACTTCTCCTAGAATGACTTTCATTAAGCATAAGTCATAAGACTATCTAGATATGATTAAGTAAACTATTAATCTTATTAAAGGTCTCTAGGAAGAAAAAATTTCATGCGATGAGATTGTTTTAGAAAAAGCGACGATATATATAATCTAACAATAATTTTTAAAATATTAAGAACCCCCAGCATATGCTTTATATAGCTTGCTGGGGGTTTCTCATACAATATGGATCGAGCATCTTGCATGTATAAACAAATAGGCTATTCAAAGTAAAATTACTCAAACTTTGAATAGCCTTTCCTCTTCAAATAGTCTTTATTTAAATTGGATTATGTTATTGGATTTTCTTACCTACAAAAACGATTTCTTGATGTGATACTTCAACCGTGCCATCTTTTTGCTCTTGAAACACGGGTTTTTCAATACGTTTTACCGGCATATACCCTTGCATTTTCATTCGTGACAAACAATCAGCAATTGTTTCATTCTCATTTACTTTGAATTTCATGTTCTACTACACTTTCCAGTTCTTCTGGTTCATAATCTTTAAGCTTTCTACGACGAATGCCTTTAGTCCAGAATCCACCATGTATGTTTCGAGGTTCATACGCAATGATAAATGCTTTCGGATCTAAATTTTTTATCGTATCCATCAATTTACGTTCATATTTTCTTGGTGTTAAAATTTGCATCACCATACGACTACCATCTCTACCAAACGCAGCATAGTGCGTAACGCCATATCCTAAATTTCGAAGTTCATTCGGTAAATCTAACTCATATTCTGCTGAAGTTACATTTACAACTGTATAACCTAATGCCAGTTTTTCTTCTATTTTCATACCAACAATGATACCTATTGAAAAACCAAATGCGTAGGCAATAATATTTTGAATATGGTCTAAATTAGACATAACCAAACCTAAACCAACGATATAAACTAATACTTCTAAAAAACTAACTGATGCAGCAATATAACGATAACCTTTCAACGTTAAAATTGTTCGCATCGTTAAAAACGTTACATAACAAACGTTAATGATAAATATAGTTAGTACCATTAACCATGGATTTTCTGTTACGAATGACATAAGGCGCCCCACTCTCTTTCAATTACACTTTAAATACCAAACTGCTTCAACCTAACCTTAATGAATGCATATTAATATAATATAGTACGAAAACTCTCATAAATAAATAGCGAATTTGTCATAAATAAAAATTTATTCTCAAATGAACATACTTACTTTAGTTCATACACTTTCAATTTATACACTGAAGTAGTCTAGCTGAATGTGGTTTAATGTTATTAATTCTAACTCATATTTAATTTAAGTCACACGTTAGAAGAAAAAATTAAATTAGGATTTTGGCCACGTGTATCTTGTATATGCAAGTTCACGTTTGTGTGCATTTCGTATATAATGATTTTCAATTACTTTTTGTTCTTCTGGCGTAACTGGCTTACCTTCTAAATAATTATCAATCGCCTCATAAGTTACACCTAATGCATCTTCATCTGGAAGCTGTGGTTTATCATCTTCTAAATCAGCAGTTGGCGTTTTTTCATATAATTCCTTTGGCGCACCAAGATACGCTAATAATTGACGACCTTGTCGTTTATTCAAACCAAATATAGGTGCGATATCTGCAGCACCATCACCGTACTTCGTATAAAACCCAGTTATATTTTCAGCTGAATGATCTGTTCCTACTACAATACCTTGTCGGTTTGAAGCAATTGAAAATTGTACTTTCATACGTTCACGCGCTTTTTCATTTCCTTTTTGGAAATCTGTAAGAACAATACCAGCTTCTTTTAATGATTGCACACTTTGATCAACTGCAGGCTTAATATTGACTGTTACTATTTCATCTGGTTCAATGAATCGCAAAGCTTGGTCAACTTCATCAGCATCTTTTTGAACTCCATAAGGTAATTTAACTGCAATAAACGTACAATCAATGCCTTCTTCACGTAATTCGTTAACAGACATTTGTACTAGTTTTCCAACTAATGTAGAATCTTGTCCTCCTGAAATACCTAACACTAAAGATTTTATAAATGAATGTGATTGTACATAATTTTTTATAAATTGCTTTAATTCCATAATTTCTTCAGCACTATCGATACGCTTTTTCACTTTCATTTCTTGTACAATAACGTCTTGTAATTTACTCATTATCTTCTTCCATCTCCTTAACGTGTTCCGCAACTTCAAAAATACGTTTATGTTTATTATCCCAACATGCCTTGCTTAAATCGACTGGATATTCTTGTGGATTAAGGAAACGCTTATTTTCATCCCAAATAGATTGTAATCCTTGTGCTAAATATTCACGTGATTCATCTTCTGTTGGCATTTGATATACTAATTTACCATTTTCATAAATATTATGATGCAAATCAATGGCTTCGAAAGATTTTATAAATTTCATTTTATAAGTATGCACTGGATGGAATAATTTTAAAGGTTGTTCATCGTATGGATTTTCATTTTCCAAAGTAATATAATCGCCTTCTGCCTTACCTGTTTTCTTGTTTATAATGCGATATACATTTTTCTTACCTGGCGTCGTAACCTTTTCAGCGTTATTTGATAATTTAATACGATCACTATATGAACCCTCTTCATTTTCAATAGCTACAAGTTTATATACTGCACCTAATGCTGGTTGATCGTATCCTGTAATCAGCTTTGTACCAACGCCCCAAGAATCTACTTTTGCACCTTGTGCTTTCAAACTCGTAATCGTTTCTTCATCCAAATCATTAGACGCGATAATTTTAGTTTCAGTAAATCCTGCTTCATCAAGCATACGTCTTGCCTCTTTAGATAAATAAGCGATATCTCCAGAATCCAATCGAATACCTACAAAGTTAATTTTGTCACCTAATTCTTTTGCAACTTTTATTGCATTTGGCACGCCAGATTTTAAAGTATGGAATGTATCTACTAGGAACACACAATTTTTATGTCTTTCAGCATATTTTTTGAAGGCAACATATTCATCTCCATAAGTTTGGACAAATGCGTGTGCATGTGTACCAGACACAGGTATACCAAATAATTTACCTGCCCTAACATTACTTGTAGAATCAAAGCCCCCGATGTAAGCAGCTCTAGCGCCCCACAATGCTGCATCAATTTCTTGCGCACGACGTGTACCAAACTCCATTAATTTATCATTTGATGCAATTTGACGAATTCTACTAGCCTTTGTTGTAATTAGTGTATGGAAATTTACAATGTTTAATAAAATTGTTTCTATTAATTGCGCTTGAATCAATGGTGCTTCTACGCGTAACAATGGTTCGTTACCAAAGCATAATTCGCCTTCTTGCATCGAACGAATGCTTCCTGTGAATTTTAAATCTTTTAAATATGATAAGAAATCATCCTTGTAGCCAATAGACTTTAAATATTCCAAATCAGATTCTGAAAATCCAAAATGTTCTATAAAATCAATGACGCGTTTTAAACCATTAAAAACAGCATAGCCACTATTAAATGGCATTTTTCTAAAATACAAATCAAATACAGCCATTTTTTCATGAATATTATCATTCCAATAACTTTCAGCCATATTTATTTGATATAAGTCATTATGTAACATTAAACTGTCGTCTTCTAATTGGTACACTTGTATCTCTCCAATCGACCTAAATATTTTCTTACATTTTATCATAATTCATTTTTTTATATACATAAGAGCCCCTTAATTTCCATACTTTTAATTAAAATCAACCAACAATTTAATGACATATACATAATTTTTAAGAGTATTTTAATAATGTAGACTATAATATAAAGCGAGGTGTTGTTAATGTTATTTAAAGAGGCTCAAGCTTTCATAGAAAACATGTATAAAGAGTGTCATTATGAAACGCAAATTATCAATAAACGTTTACATGACATTGAACTAGAAATAAAAGAAACTGGGACATATACACATACAGAAGAAGAACTTATTTATGGTGCTAAAATGGCTTGGCGTAATTCAAATCGTTGCATTGGTCGTTTATTTTGGGATTCGTTAAATGTCATTGATGCAAGAGATGTTACTGACGAAGCATCGTTCTTATCATCAATTACTTATCATATTACACAGGCTACAAATGAAGGTAAATTAAAGCCGTATATTACTATATATGCTCCAAAGGATGGACCTAAAATTTTCAACAATCAATTAATTCGCTATGCTGGCTATGACAATTGTGGTGATCCTGCTGAAAAAGAAGTTACACGCTTAGCAAATCACTTAGGTTGGAAAGGAAAAGGTACTAATTTTGACGTGTTACCACTGATTTACCAATTACCTAATGAGTCAGTTAAATTTTACGAATATCCTACTTCATTAATTAAAGAAGTACCTATTGAACATAATCATTATCCAAAATTAAGAAAATTGAACTTAAAATGGTATGCAGTCCCTATCATTTCCAATATGGACTTAAAAATCGGTGGCATTGTATATCCAACTGCACCCTTTAACGGTTGGTATATGGTAACTGAAATTGGCGTACGTAACTTTATTGATGATTACCGTTACAATTTACTAGAAAAAGTTGCAGATGCGTTTGAATTTGATACACTTAAAAATAATTCATTTAATAAAGATCGAGCACTTGTTGAATTGAACTATGCTGTGTATCATTCCTTTAAAAAAGAAGGCGTATCAATTGTCGATCATTTGACCGCTGCAAAGCAATTCGAACTATTCGAACGTAACGAAGCACAACAAGGTCGTCAAGTTACCGGAAAATGGTCTTGGCTAGCACCGCCATTATCTCCAACATTGACGTCAAATTATCATCACGGATATGACAATACAGTAAAAGATCCAAACTTTTTCTATAAAAAGAAAGAATCAAATGCTAACCAGTGCCCTTTCCATCATTAAGTTAGTAGAGGTGTAGCATATGCAATTATATTATTTAGGCCCTAAAGGTACATTTTCATATTTGGCTTGTCGTCAGTATTTTTCTGAAAATGAAGCAACTTTTCAACCAAAGTCAAATTTATTTGAAGTCATCAAGGCAGTTGCAGATGATGACACATCGATTGGTGTTGTCCCTATTGAAAATTCTATAGAAGGAACAATCAACATTGTGGCAGATGCACTTGCACAGCAAGATGTCTTTGCACACGGTGAAATACGTTTAGATATTAACTTTGCATTATATGGTAATGGAACAGATTCCATTTCTGATATTAAAAAAGTGTATTCTATTGCACCAGCAATCAGTCAAACAACAAATTACATACATCAACATCAATTTGACTATGATTATGTCGACAGTACAATTCAAAGTTTGACTAAAATTGAAAATGGCGTTGCAGCAATTGCACCTTTAGGTAGTGGCGAAGCTTATGGTTTTACACCTATTGATACACATATTGAAGACTATCCACATAACGTGACACGTTTTTTAGTTATAAAAAATCAGCAGCAATTTGATCAAAATGCGACATCATTGATGTTTTTAATTACACCAATGCATGATAAACCTGGGCTGTTAGCAAGTGTGCTTAATACATTTGCTTTGTTTAATATTAATTTATCCTGGATTGAGTCTCGTCCTTTAAAAACACAATTAGGTATGTATCGATTTTTCGTTCAGGCTGATTCTGCAATTACAACCGATATAAAGAAAGTCATTGCTATTTTAGAAACCTTAGATTTCAAAGTAGAAATGATTGGTGCTTTTAATTAAACTTTATTTTCTAGGTTCTACAATTTAAATAAAATAAAGAGTCAACCAAGGATTAAAATAGGAATCCATCCTTGGTTGACTTTCTTTTGTTTGTATTGTTTTTACACGATGCTGCGGTATACGTTTCATTACCACTCGTTCAAGCAATTGCTAATGTAACCTTTTATTTTTCGTTCTAATCTGCAATTACTATTTCAATGGCAGTGGTTGATTTATATCAATACCTAAAACTATAGGCATTACATAATACACGACTAAAATAATAATTATTGCACTGATTAAGTTTACCCAGAATCCTACTGATGCCATTTGTTTGATAGATATTTTACCTGAACCAAAGATAATTGCATTCGGTGGTGTCCCTACTGGTAACATGTATGCACAGTTAGCCGCCATAGCTGCAGGTGCCATAAGTAGTAATGGATGCACTCCAACAGCAACAGACAACGTTGCTAAAATCGGTAAAATCATCGTTGCAGTTGCAGTATTAGATGTCACTTCAGTTAAAAATAAGACAAAGATTGTTATGACAATTACAATAAGAATCGGACTAACACCATTTAATGATTTCAACTGTTCGCCTAACCATTTTGCTAAACCACTTTCAGAAATACCTTTCGCTAATGCTAAACCGCCACCAAATAAAATTAATACACCCCAAGGGAGCTCTTTTGCAACTTCCCAGTCAATGATACGGCGATGTTTTTCAGTATTTTTAGCTGGAATAATAAATAATAATATTGATATAAAAATAGCAATCGTACCATCTGCAACAGATGACGTAACTTCCCATTTTTTCAGAAGAAACTCTCTTGTAATCCATAATAAGCTGGCAAGTACAAAGATAGTTTGTACTACCTTTTCTTCATACTTCATTTTGCCAAGCTCGTCTAACTTTTGTTTAATTAACGTCTGACCACCAGGTAAATATTTCAAATCATGTCTAAACGCAACATATCTTAAATAGAGCCAAGTAATACCTAACAAAACAATGACCGTTGGAATCCCTACAATCATCCATTTAGCAAAACTAATTTCATGTCCAAAATGTTGCATGTATTGTCCTTTTAAAATAATTAATGGCGGGGTTCCGATTAATGTACCCAAGCCACCAATCGTACCTGCATAGCCAATTGCTAAAACTAGAGATTTTTCAAACTTTTGAATACTTGTTTGATTCGTATTGGCTTCTTGTAAATCATGTGCTTCCTTAATAATTGCTAAACCAATCGGAATCATAATCATTACAGCTGCAGTGTTCGATACAAACATAGATAAGAATCCTGTTGCCACCATGAATCCAAGTAATATTTTTGAAGTGCTTGCACCAATTAAATTAATAATAGTCAAAGCTACTCTCGTATGTAAATTCCATCTTTCCATTGCAATTGCCAAAATAAATCCACCTAAAAACAAAAAGATAATATCATTGCCATATTCGGATGATACTTGTTCTGGTGTAAGTATGTGACCTAATGGTAATAACACAATTGGTAATAAGCTCGTTGCTGCAATAGGAATTGCTTCAGTAATCCACCAAGTCGCAATCCATAAAGTAATCGCTAAGACATATACGCCTTTCCAAGGTAAGTCTTGTGGATGAAAGAACAATAATGTTAATAGGAAAAGTAATGGACCTAATATTAGTCCAATAAGTTGTCCCGCACTAAACGGTTTCTTTTTCTTTGATTTTGAAAAGAATGTTAAATACCTTTTCGATATCATTGATTGATGTTGATTGAAATAAGCCATAAATTTCCCCCTCATGATGATTATGACAAGCTACTTCAACTCACTATATTAGAGTATAGAAAGTTGTCTATCTTGTATTATCATTACCGTCAAAATACCCCTTTTATCAGATAATTGGGTTTATTATAGCATATTTATACCGTTTTATGAATGCGCTTTCAAAAATTATCTACTATTCTTAATCCTAATGTCATGCGAAACTTTTTACTTTTTTATTTCATCTATATTGATTGTAGTAACTTGAATACCCGCTTCAACAGGACTTAAAAACACTGTATCAATATCTTCTAAATGAATTGATTGAGTCGAATTATTGAATGTATTCCCAACGATTAATACATCTTTATGTTTAACATTATTATAATTACGTACATGTATCGCATCTTTAGACATTGATCCTTTAAATTCATTTCCAATTATATTCATATTTATGCCTGCTTGGGAACCTAAGTCTTTTCCTGTCATCACATCTGCTGCATTTTTACCATCTCTAACTCCTAAATATCTAATACCACCCTCACAGTTAATAAACTTATTATTAATAATGAAAGCATCTTTATACTTCAAGGGAGTTAATGCATAACCTTGTATATCTTCAAATATATTATTTCTAATATGAATATTCTCATAGTAACGATTATGTCTACTTGCATGTGAGCCAATAGCACGATTCCAACTTCCCATTTCGGGCAATTCTGAAGGTCCAAAATAACAATCTTCGATAACGACATTTTTCGTTATCGTACCATCTGTCGTTCCGAATTTTGGAAAAGCACCAGGTACTTGAATGTCTAATTGTATTGCTTCAGAATAAAAGCGTTCGCCACTATAGTCTATGAATCCTTCAAATGAACAGCTTTTAATATAGAGTCCGTTAATCCCACAAGCATCAATTGCATGACCACTCACTACATTCTTAATGGTCACACCTATTAATTGAATATCTTCAGCATGCCCAATGCACATAGCTGTATTGTTATAAGGATACGATACACCATTCATATCAAACTTGCCGCCTTTAATATGAATATGACTGTGTCCATTATAACCACGATAAAAACCAAAGCGATGACCATTTTTTAATAAAGGACCAGAATGACATCGGCGTAAAATAGTTTCATTATCTAACAAAAGTGTTGTATTGCCATATATCGTTAATGGTTTGCAAATATCATACGTCCCTTTCGGTATATAAACTGTCGTTGGTTTACATCTTCCACGATTTAACGCACGTTGTATTGCTCGAGTATCTTTAGTTTTGTTTATGCCTGTTAACCCATAATCTTTCATATTGATATACATAAATCGTCATCCTTTGTCTATTTTCTAATTACTCATATATTAACCAATTATTCAAATTATAATCGTGTTAGGTTGATTTAGCAGATAGTCATAAATCTCGTGATGCCATCTATTAGCATTTTTATATTCAAAACATCAACACTTGATATTAGTTCTAAGTTTGTCACATTTAGTATTCTATTACAGCTATTTTAAAACTATCGCAAAAACTTCTTATATTATTTGTTGATTGCGTGATTTGCTCTTCCAAAAAAGTTGATTAATCTATATACTTAATCTATATTTATATATTAACCATTAGGGTTAAAAATTACTCTAGCATTTATGAATAGATGGGAGTTTATTTTATTATATAGGAGAGATGTTGAATGACACATCGCGCACTATTAGTTGTTGACTATTCATATGACTTTATCGCAGATGACGGCTTACTAACATGCGGTAAACCTGGACAAAATATTGAAGATTTTATTGTTTCTCGTATCAATGACTTTAATTATTATCAAGACCATATATTCTTTTTAATGGATTTACATTATTTACATGACATTCATCATCCTGAAAGTAAATTATTCCCACCACACAATATCGTAGATACAAGTGGTAGAGAATTATACGGTAAAGTAGGTAAATTATACGAAACAATTAAAGCGCAACCTAATGTACATTTCATTGATAAAACGCGCTATGATTCGTTCTTTGGTACCCCGCTTGATAGTTTATTGAGAGAAAGAAGTATTAATCAAGTCGAAATCGTTGGTGTATGTACCGATATTTGCGTGTTACATACAGCAATTTCTGCATACAACTTAGGTTATAAAATTTCAGTACCTGCTGAGGGAGTGGCTTCATTTAATCAAAAAGGGCATGAATGGGCACTTGCACATTTCAAAAACTCATTAGGTGCAGAGGTAGAACAACACGTTTAAATCGTGCTAAAATAATTATAAAGAATACAATTTACAAGGGAGATATTTGACAATGGCTAAAACATATATTTTCGGACATAAGAATCCAGACACTGATGCAATTTCATCTGCGATTATTATGGCAGAATTTGAACAACTTAGAGGTAATTCAGGAGCCAAAGCATACCGTTTAGGTGATGTGAGTGCAGAAACTCAATTCGCGTTAGATACATTTAATGTACCTGCTCCGGAATTATTAACGGATGATTTAGATGGTCAAGATGTTATCTTAGTTGATCATAACGAATTCCAACAAAGTTCTGATACGATTGCCTCTGCTACAATTAAGCATGTAATTGATCATCACAGAATTGCAAATTTCGAAACTGCTGGCCCTTTATGTTATCGTGCTGAACCAGTTGGTTGTACAGCTACAATTTTATACAAAATGTTTAGAGAACGTGGCTTTGAAATTAAACCTGAAATTGCCGGTTTAATGTTATCAGCAATTATCTCAGATAGCTTACTTTTCAAATCACCAACATGTACACAACAAGACGTTAAAGCAGCTGAAGAATTAAAAGATATTGCTAAAGTTGATATTCAAAAGTACGGCTTAGATATGTTAAAAGCAGGTGCTTCAACAACTGATAAATCAGTTGAATTCTTATTAAACATGGATGCTAAATCATTTACTATGGGTGACTATGTGACTCGTATTGCACAAGTTAATGCTGTTGACCTTGACGAAGTGTTAAATCGTAAAGAAGATTTAGAAAAAGAAATGTTAGCTGTAAGTGCACAAGAAAAATATGACTTATTTGTACTTGTTGTTACTGACATCATTAATAGTGATTCTAAAATTTTAGTTGTAGGTGCTGAAAAAGATAAAGTCGGCGAAGCATTCAATGTTCAATTAGAAGATGACATGGCCTTCTTATCTGGTGTTGTTTCTCGAAAAAAACAAATCGTACCTCAAATCACTGAAGCATTAACAAAATAATACTATATTACTGTCTAATCATAGACATGTTGTATTTAACTAACAGTTCATTAAAGTAGAATTTATTTCACTTTCAATGAACTGTTTTTTATTTACGTTTGACTAATTTACAACCTTTTCAATAGTAGTTTTCATTCCTTTAGCTATCCTAACCCACAGATTAGTGATTTCTATACAATTCCTCTTTTGTCTTTACATTTTCTTAAAATATTTGCGATGTTGAGTATAAATTTTTGTTTTCTTCCTACCTTTTTCGTTATGATTAAAGTTATAAATATTATTATGTACACGATTCATCGCTCTATTTTCAACTTTCAACATATATAATTCGAAAGACCATTTAAAATTAACGGCCACAACAATCAAATCAATTAATCACTTTTTCCAAAATAATCATATAAGGAGGTTCTTTTCATTATGAATATCATTGAGCAAAAATTTTATGACAGTAAAGCTTTTTTCAATACACAACAAACTAAAGATATTAGTTTTAGAAAAGATCAATTAAAGAAGTTAAGCAAAGCTATTAAATCATACGAGAGCGATATTTTAGAAGCACTATATACAGATTTAGGAAAAAATAAAGTCGAAGCTTATGCTACTGAAATTGGCATAACTTTGAAAAGTATCAAAAATGCCCGTAAGGAACTTAAAAACTGGACTAAAACAAAAAATGTAGACACACCTTTATATTTATTTCCAACAAAAAGCTATATCAAAAAAGAACCTTATGGAACAGTTTTGATCATTGCACCATTTAACTATCCTTTTCAACTAGTATTCGAACCTTTAATCGGTGCTATTGCAGCAGGTAATACAGCAATTATTAAACCATCTGAGTTGACACCAAATGTTGCACGAGTGATTAAACGATTAATCAATGAAACATTTGATGCAAATTACATTGAAGTTATTGAGGGAGGAATTGAAGAAACGCAAACGTTAATTCACTTACCTTTTGACTATGTCTTCTTTACAGGAAGTGAAAATGTAGGCAAAATCGTTTATCAAGCTGCCAGCGAAAATTTAGTTCCTGTGACATTAGAAATGGGTGGTAAATCTCCAGTCATCGTTGATGAAACAGCGAATATTAAAGTTGCTAGTGAGCGCATTTGTTTTGGGAAATTCACTAATGCCGGCCAAACATGTGTTGCACCAGATTACATTTTAGTACACGAATCTGTAAAAGATGATTTAATCACAGCCCTATCAAAAACGTTGCGTGAATTTTATGGTCAAAATATACAACAAAGTCCAGATTATGGCCGCATTGTAAACCTTAAACATTATCATCGTCTGACTTCATTACTTAACAGTGCACAAATGAATATTGTATTTGGTGGTCATAGTGATGAGGATGAACGTTATATAGAACCAACATTGTTAGATCACGTTACAAGTGATTCAGCAATTATGCAAGAAGAAATTTTTGGTCCTATCTTACCGATTTTAACGTATCAGTCATTGGATGAAGCAATAGCCTTTATTCACCAAAGACCAAAACCTTTGAGTTTATATTTATTTAGCGAAGATGAAAATGCTACACAACGTGTAATAAACGAGTTATCATTTGGCGGCGGCGCTATTAATGATACATTGATGCACCTAGCGAATCCTAAATTACCATTTGGTGGTGTTGGCGCCTCAGGTATGGGACGCTATCATGGTAAATATTCATTCGACACTTTTACACATGAAAAAAGCTACATTTTCAAATCTACACGATTAGAATCAGGTGTCCATTTACCACCATATAAAGGTAAATTTAAATACATCAAAGCTTTCTTTAAAAATTAATTTTTGAGACAAAAATAAACCATGCTTCCATAATTTGATGTTCTTGAAAACAATAAATTTCAAGGTATACACAAATTTTTTGTAAACATGGTTTTCTTTTTATCATGATTAATTAAAGATTAAAATATGACACATACACCTTCAGATGCTACACGAGTATTATCACATAGAGTAATTTTACCTGTTTCTTTACTTCTTTCAAAAACAGTTACAACTGAATCTCCTTGCTCATGAGCACAAACTAAAAGGTCATCTGATGAGGCAATATTAAAATCTCTTGGGAATTGACCACCACTTTCAGTAATTGTTACTAGTTCTAAGTGTTGACCATTATCAAGAACTTTAAAAATTGCAATGCTATCATGCCCTCTATTAGATACATATAAGAATTGTTGATCATGAGACAAACGCACTGCTGCAAGTTTAGTATCTCCATCAAAGTTTTCAGGAATTGTTAAATGACGCTCGAGCTCTTCAAATTTACCGTCATTATATTCTGCAACACTCACAGTATTTGATAATTCGTGTACGACATAAGCAAATTTTCCATTATCATGAAATTCAATATGTCTTGTCCCATCACTATCTTTAAATAAAGATTCTTTATAAAATTCAAACCCGTTGTCATCAAATTTATAAGTAACGATACGATCAGCACCTAAATCTGTTACTGCAACGTACTTACCATCTGGAGTTTGATTAATATAATGTGCGTGTGGATGATCTTGTCTTTCATGTGTACCTGTTGGAAAATCATGTGCAAGTTCTTGAATTAGACGTATAATTTCACCTGTGTGCGTATTTAATTCATACATACGTATGATGCCAGCACCATATACCGCTTCAAATAAATATCGTTTATCTTCTGAAATCGATACATAACAACCTGTACCAGCTTTTGAAGACAAACATTTATTTAATAAATGCAATTCACCATTGTCATCAATTTTCAAACTCGCAACACCGCATTGTTCTCCTTCTTTGTTGATTCCATATAAAACTTCGTTATTACGCACCAAATATGTAGACGCTTCTAATTCAAATCCTATTTCTAATAAATCAATACGTGACTGATTTTCGTTTAATTCAAAACGATAAATCCCTTTACCATTCTTTTTAGTGTAAGAACCAATATATCCATTTGTCATTACTTTTACCCCTCCATGTCAGTCTTATTTTCATTTTATTAAATTTTAGCTAGAATTAACAATCATTTATCATTTCCTTAACGCTAAAACTGTTTAACTACTTTAAAAGAACTATTTGCTGTGATATGTCATTATTCGATTTTAATTAATCCCTCTTTTTTACTTACACGAGCATTAATTATTAACGCGTTTATGCTTCCACAAAATTTTTGTTGCAAAACAGAACACATGTTCGTATAATGTAATTATCAGATTGGGGTGAATTAAGGATGACAAGTTATGAAGAAGAAACTGATTATCGTAACGTTCCAAGAGAATTACTAGATAACAATATACCTATGGGAAGAGGCATGATTAAATGGGCTCCTTTTGCAACATTACCCGAACAATTCGAAACGATTCAACAATACATTATCGACCAAAACAAAATTACACGTCCTGTATTATCAGATGATCAATTGGCTGAGCTAAACATTCGGCTACACGAGGCGCTACAATATGCCCAACCTGTAGAAGTTAAATTTTATAATAATGGCTTTGTAGATTCAGTACGCTTAACCATTTATCGTATTGATGCTATTAATTATGAAATTGATGGTTATGTTTACAATCAGCAACAACGTCAAAAAATTTCTATCTTTGATATCTTAGATATTGTCTTGTTACCTTAATGCTTTGAACATAATTAAACAGATTGAGTATATGCATATAAGATGATTTTTAACATCATTTTTGGATGATAGGATGTTGCGCCACGATGATGTCTGAATTCATCGAATTCGCTATCAGGTATTGTTTCAACAATTTCATTAACATATCGTGAAATATCATTTTGAGGGATTCTAACAGAAGTTTCTATTGGTAGTGTAGTTGGGTCATGTTATAATTTTTATACATAAGGCACCTCGTTAATTTAGTTTAGTGGTATTTATTAAATTATAAGAAGGGACCCAACACAGAAAATTCATTTTATTGAATTTTACATTTATGTGCAAGTTGGGCAAAGTGTCTTATTTTTTAAAAGTATTTCAAAGTAAAATTACATGTTAATACGTAGTATTAATGGCGAGACTCCTGAGGGAGCAGTGCCAGTCGAAGACCAAGGCTGAGACGGCACCCTAGGAAAGCGAAGCCATTCAATACGAAGTATTGTATAAATAGAGAACAGCAGTAAGATATTTTCTAATTGAAAATTATCTTACTGCTGTTTTTTAGGGATTTATGTCCCAGCCTCTAAATGTTATTAGTTATTTTTACTTTCAATATCAGAAATAATTTCTTTAGTTTTTCTTTCAATATCTTCAAAATCTTTTTTAAAGATATAAGCAAATGCTACTACACCAACACCAGCAACTAATGTTGTAATAGCAACTAAGCTAAATACGAATTTAAACACACATTTAATAAAATTCCACATCTCAATTTCACCTCTGTTAAATTAAATACCTATCTACATTTCATTATACTATCATATATAGAATAATCATTAAATAAATACCCACTTTTACGAAATATATTCATCAAATTATATAGTGAGCAAGCTAATGATTATTTTCAAAAATGCCGAGGAACCTCTGTTTCAACGTGACATGACCTTATATGCTAATGTTAACAATGACTATTATCGTGAATGCTAACTTAAGATTGTTATTTATGATAAGATGATTTTAAGTTTTTAACTTAATATCCCCACCATCTATAAAAATATGTTTTAACTGATTGATAAGTCTTATACACCGAGAAATCACCTCAAACAATTTTATATTTCATTTAGTAAAATATAACTTTATTTAACATGACATTCAATATACATACGATTACTATTTATTTACAATATATTACAACTAAAAAGAAAGGGGCCGATGATATGCAACAAGTGATATCAGATATTATGACTTTTAGAGGTTCACATTTCGAGTTAGGTGTTAAAACTGGTAAATGGCTTCAACAAACACCTCTTCTAAAAAATCGAGAAAAAGAATGGAAAAAACGTGTCCCACGTTTCGATATAGATGTAAATGAAACTTATCAAATATTCCAAACTTACGCACCTCAAATATGGGAAGAATTAATGGGACTACAAAGTATACTCAAAATGCCAACACGCCAAATTATTTTAAACTTTGGACATTATCGTTTTACCGATTTAAAAGAAAGTGGTTGCACGGTCTTTCAAGGCAAAGACTTCATGGTTAGAAATTATGATTACCACCCTGCAACTTATGATGGTCGCTACTTACTATATCAACCTACAGATAGCGGTTTAGCTCAAATTGGTCCTGTATCAAGGGTAACTGGAAGAATGGATGGTATGAATGAGTCAGGATTAACTATGGGCTATAACTTTATGCACCGGAAGAAACCAGCAAATGGTTTTGTATGTTATATGATTGGTCGTCTAATTCTTGAAAATTGCCGAAATGTAACAGAAGCAATACAATTATTGAAAGAAATACCACACAGAAGCTCATTTAGCTACATACTGATGGACAAATCATTGAACCATGCAATTGTTGAAGTGACACCGAGATCAATAGATGTTCGTTATGATAATATATGTACAAATCATTTTGAAATATTAACACATGAAAATCGTAATTATACAAAAGAATCTAAAGAAAGACTGGCGCGTACCATTTCACAAACTAATGATAATTTAGATATGACTACAGCATTTAAGTTATTCAATAATCCTCAGTATGAAATTTACAGTAAACTATTCAAAAGCTGGTCTGGCACCATCCATACATCAATGTATCAACCTGAAACATTAACTGCATATTTTACATTGGGAGAAAATGCGCCACCAGAAATAATAGATTTCAAATCATGGTTAGATGGTCAAGACCTTAATATCACTCACTTTACTGGCAATATAGATACCGACTTAACTTTTGCCAACAAATAAATAACACCGATATTAGAGAAATTATGCTTCCTAATATCGGTGCTTACATCCTTTATTTATTCAACTTTGATATTACCATCAATCGTATAAAATTCTAAAACATTGTCGCTTTTCCCAACTTTACCATTAGTAAATGTTTTATTTTTAACTACGCTATCACCCGTTCCCGGATTTAGCTTTAGTATAGTGTCTTCAGGTTTACTATCATACTTAAAACGAATATCTCCTTGTTTAGTAGAAGCTTTTGCATCTACTTTTGATGGCATGTTTTTAAATTCAATGTCACCATGATCGTTTAAAAATATGGATTGTTTAATTTGACTCTTGTCGATTTGTAGCGTACCAATAACAACTTTAATATTGCTATTTTTAATGTTACTTTTACTAATATAAGTAGAACTATTATTTGTCTTTGAATCTAGTGCGTCAAGATTTGAGTTTTTAATAACTACTTCACCGTTAATGCTTTGAATACTTGTGTTCTCTAAATCAACATCACTGATTCTAACACTTCCTGCTCCAGATGATAGATTTAAACGTTTAATCATTTTATCAGGCATTTCAATCGTTAACGTTTTCTTATTCTCATGAAAAGGATTCATATCAATTGCATATCCTCTTGTCTTAGACCTTTTATCACTAATCTTCAACGTCTTATCTACTATATTAATTAATATATCATTGTCACCATCATATTTAACTCTAAATTGATTCCCCCGTTTTATACGAAGTTCTGTACTATCCAAATTTATAGATACATTGTCAAAAGCATCGTCTTTGAATGTTTTATCATATTGTTTAGTACCATATTTGTTTTTATCATAGCTGAACCAAATAATGGTTGCTGCTGTAAAAAAGACAACAAACACTAAAAGCCCAATAAAAAAGAATTTCTTCATTTTCTAACGCTTCCTTTGACAGTTTTAATATACCAAAGTAAATATTTTAAGATTAAACGATAAATGTATTCTAAAATCTTAAATATGACAATGATAAATACTAATCCTAATCCTGAATATGATATGGCAAAAAATACATTACTAATTGAGTCTACAATTCCTCTGGATATTGCTGATGCTAATAAAATAATTGGACAAAACAGCAGCAAAAGTGATATTAAAAATAATGCTAATACAAATAATCCAACTATAGATACTGGTATAAGGATGACAAAAATAGATAGAATGCCTAAACTTAATGAAGCAGCAACAGCTCTTGAAATATTTTCAAATGTTGGTTTAGATTCAGCATAATCAATAACACTTCTAGCTTTTGTTTCAGCTGCAACATCTTGTGGGTCTTTTAACTTCTTTAAAATTTCCCCTTCATCAACGCCATTAAGTTCTTGCTCATAAAAATAACGTTCATATTCATACATTTTTTGATCTCTTAAATGCCTAGGTAGCGCATCAAGTGCTGTTTCTAATTCATTTAAATAAGTAATCTTGTTCATATAGGTCACTCATCCCAATAAAATTATTTATTCGTTTTTTATAACTTTAAGACCTAAAGCTATTTACTAAAAAATTCAATACGTTTAATTTCTAAATCTTGATAAAGTAAGTTTAATTTTAAATGGTTATCTCTATCAATATACTTTACCGATGAGAAATCATTGCCAACTTTTGTTCTTTTATATCCGAATCCAAGATTTTCAATCGCGTTATTTATCGGCGAACCAATTCCCCCATCAAAATTAGTATGTATCTTTTCATCTCTTACTAATATTATCCCCTTAACGATGTTATCCTTTTCTCTCACTTTAACGGTAAGATCAGGGTGAGCTTTACTGTTATAAAATTTAAAACGATCAAACTTAATTTTTTTATTTACTTCATAGCCTTTTTTATCAAACTTCTCATTTAATTTAATATCGTTTATTTCAAGATTAGACAAATCCACAGTTTTCGTATGACGATATTGATATAAACCAATTAATACACCAAAAGAACAGATTAAAAATAATATAAACACAACCCAGCGATTTTGAATACGCACTGATGTCACCCTTTCTTTGTACTTATTTAAATATAGCATAAGGTGCCTCCCGTTTCATCCTTAACAAAAATTAACAAAGAATTTGCAATTAATTTATTTCATTACCTTTTATTACTATAAATTGGTATAATGTTGTAAATGCTAAAGGAGGTTTTTACAATGACAAATTTAGAAACTTATTTCAAAAATAGCCAACCCTTAAATGAATACATTGATGGAATGAAGACAAATCAAGATACCGTTCTCAGTATCTATCAATCATTTGAGTTACCAGAAGATGATTCACGCATCAAAAAAATAAAAGAGATGAATTATTCTAAAGTATTAGTAATTACTGAAGACTGGTGTGGAGATGCAATGATGAATCTCCCAATTCTAAAACACATCAGTGAAGCATTAAATTTAGAAGTACGCGTGTTCCATAGAGATGATGATACAAAACTGATCGATCAATATTTAACAAATGGTAAATCACGTGCAATTCCTATCTTCGTATTCTTGAATGATCAATTCGAACAAGAAACAGTTTGGGGACCAAGAGCAAATGAAGTCCAAAAATTTGTAACTGATGTTCGTGCTGATAAATTACCGAGCAAAGATCATCCAGACTATGCAGATTTAGAAAAAGAAACACACTTAGTTATATCAAACCGCTATAAAACTGACGCTTCATTTTGGAAAGCAGTTTATAATTCCATCCTAAATAAATTAGAAAATAAATAAATTTACAATAAGACAAACTTTGAGGTTGGGAAAATTTAAAATTCCCAACCTCAAAATTATTTTTATTAAATGTCTTTTTTAGCGACATATAAGATATTCAAAATGAAGAATATCACTATAGAACCTAATGAAATTACCCATTGCCAATTGCTAAAATCAAAGTTAGAGCTAATCATTTTATCAGTTAAGTAAGCAAAAGGGATATAATCAAAAGCATCTAAAACTTTTTCACCGTATCTTGGGATAAATGTAATAAAAGGTTTAATAAACGGTACAATGAGTACTAAAAATACACCTAATGAAAATATCATTGCTGTTTTTTGTGATGCAAGTGTGATTAAGAATAAAAACAAGCCAAAGAATAGTAAAAAGATTAGGAAGAACCATAAATTATCTACATATTTAGAAAACGCCAAATTTTTTCCATTACTAGATGCCTGCACAACAATCAAAATCACATAATGAATTAATGCAAATAATATTGAAATTAAAATAATTGAAATTGTTTTCGAAATAATGTATCCAACGCGTGTTTTAACTTTACTCATATATAGTTGAATTGTACCTTGTGAAAAATCACGCGTAATTGTCTTAACAACAAACATTAATCCAATTATTAACAATAACCATTTTGCTGCAGCAAATACAGATCCATAGACAATAATATGTTTCGGGTTATCCATCGAATTTGCCATAAGTATACTTTGAGTTGCAATCAAACTAGATACGACTAGTATCGCTAAATATGTTAAAGGACTTTTAAATATACTATAAAAATCATACTTAACTAAATTTAAAATTCTCATTATTTATCACCTCTTTGATTTATATTGAAGTACGTATCACGCAATGAACTTTTACGTGTTTCAATATATTTCGGATAAATATCTAATTCAGATAATGCTTTTAGTATAACTTGATAATTTTTTTGTGCATTGATCATTAAATGTCCGTCTGCTTTGTCGACATTTTGTAATTGGAAATGCTCTGCAAGATATTTTTCAGTTCTATCAAAGTCTTTATGATCAACAGTAACTATCGTTGTGTCAGATGCAACACCTACCTCCATGTTTACATCTTGAACAAAATGTCCGTCTCTTAAAAATACAGCTCTATCACAAATTAATTCAATATCTTCTAACTTATGACTTGATATTAGAATTCTCATATCAAGTTCATTTACTAAAGACTTAATTGTAGTCAGCACATCAATTGAGCCATCTGGATCCATACCATTTGTAGGCTCATCCAAGATTAAAAATTTAGGTTTATTCATTAAAGATACTGCAATTGCTAACTTTTGCTTCATCCCCATTGAATATTTCTTAACTTTCTTTTTAATATAAGGTCTCATACCAAATGCATCTATAATTTTGTCTGTGTATGCTTTATCAAAACCCTTACCTAATACTTGTGCAAATAATTTCAAGTTATACAATCCTGATTTATTATCATATAATTTAGGATGCTCAATTAAAAAACCGATATTATCTGCATTATCAATATCTACTTTTCCATCAAATTTAATAATATTACCATTCATTACTTTCATAATGGTTGTTTTACCAACACCGTTTTTTCCTATTAATCCGACAATTCTACTATCGCCAAAGTCAAAATCAATATCATTTAAAACGACATTTGAGCCGTATTTTTTTGTAATATGTTCTAATTTCATCGACTGCCTCCTTTAAATTTTCTAGTATTTATTTTATTGAGCTGTTTAAAATAATTAACAATAAGTATAACAATGCTGATAATTAGAAAACCAATATTTAAAATATATGAATATAAATCTGGGAATGATGATTGACTTAGAACAAAATAATTCACCAACACTATTGCAATTGAAAATAAAAATGGAACTAAAATGATAATAGTAAACACGTATATACCATATGGCACTTTGACTCTACGCAATTCTGTAAATTGACTAAATGCAATTGGTATAGACAAGAAGTTAGATATGACAAATGCATATGCAGTTGAAAAATAGATTGAATTTGGTTCAATCACATCTGCTTCATAAGCATATAAACTAATAACAAGCGTTCCAATTAATGTTAAAACAATGCATGTAATATAGTTGGCATTAAGCAATTGTTTTTTTGACACTGGTAAACTCATATAAAAATAATATGAATCATTACCACCTAATCTACGATTGAGTCTAAATAAGTGACCAGCATCTAAAATCCAAATAATCAATATTGTTGGACTTATAAAAGATTGCAATAGGTAAAAGAACTTTGTTGAGTCAAGCATTATATAAAAAGGATATAAGGTTAATAATAGAACATAGATGATAAGTGTATATCGTCGTAATTTAAAATTCCTAATTAACAATGCCTTCATTTAAAAACCTTCTTCCATCAATTTGATGTTTTCATGATATTTAGGTTTTCTCTTTTCAAGATAAACCATTAAGTTCTCAATAGAAGGTGTAGTGATATTCACTTTATGACCTAAAATTTCTTTAAATACTTGCGCATGTTCTGTTAATCCTATAAATCCCGTACGCTTATGTTCTTCATAAATAAGTAGAGATGCTAATTCATCATCAAGGTCCTCAGTTGCACCACTCACAACTTGATATCTTTGTAACAGTTGTTCTTTTGAACCATTTAAGATAACTTCACCGTCACTTAAGTGAATGATATAATCAGCTATTTTTTCTAAATCTGAGATAATGTGTGTCGACATGAATATTGTTTTATTTTCATCAATTAATTCTTGCTGAATTATCTCCAATAGCTCATTTCTAGCTAAGGGATCAAGACCTGAAGTAGGCTCATCAAAAATATACAATTCAGCATGATGTGAAAATGCAACTGCTAGTGATAATTTCATTTTCATCCCAGTCGAAAATGTTTTTATTGATTTATTGATTGGTAAATCGAACTTTTCAAGATAAAATTCAAATACTTGATGGTCCCATTTACGATAAAAAGGGGCAATCATTTTTTCAAGTTGCTTCGTAGTCCATCTCTCATTAAAATAATTTTCAGAGTAAACAAACCCAATACTATTCTTTAACTCTATCGGATTGAGAGCCATATCCTCTTCTAATACTCTAATAACACCAGTTTGTGGTTGATACAAATCCATAATTAACCTTATTATTGTGGTTTTACCAGCGCCATTTCTACCAATAAAACCAGTGACGAATCCTTGAGGAACTTTGAAAGAGATATTCTTTAAATTAAACTGATCACTTGAATAATTAACATTACTTAATTCTATGGCATTCATGATGATTCCTCCTCATAAATGAACGTTAAAATATCTTGAAGTTCCTCAAGTGACATTTCGATGGCTTGCGCTTCATTAACCAATTCTTTAACCAAATTTTCAATGGTAAAAAATTGTTTCTCTTTTAAAATAGAACTATCTTGCTCCTTAACAAAGGTCCCTTTTCCTCTAATTGTTGTAACAAAACCGTCTTTCTCTAAATCTTCATAAGCACGTTTGGTAGTAATCAAACTTACTTGAAGATCTTTGGCAAGTTCTCTCATTGACGGCAAATGCTCTCCAGGAGCAACATGTCCCTTTAAAATATTTTGTTTTACTTGTTGCTTAATCTGTTCATAAATCGGAAAATCACTATTGTTTTTTAAAATTATTTTCATCAACGTCCCCCTATCAACTTCTGTATATATACAATATACACAATATACACAGTTTTGTAAATATGCATGTCCATTATCAACCAGTCTTCAGAAATAACACTGAGTATTGTATTACTAGCAGTTGAATAAAATGAAATGACACTACCATTTAATCTTGCATTGTCTACTTCAATAAAAAAGACTGCTAAAACGAATGTCTTTAATCTCTACGTGACAACCGTAGCGTCAACATAAACAATCGTTTTAAACAGTCAATTCTATTTACTATTTTTACGTCGATCATTACTTCTACTTATAAAAGCACAAATCATAAACATAATCGCTGCTAATAATAATTTTATACCTTGGCTTTCATGATTAGTTGCTTGTAAATAATAACCAATAATAAATAAAATAATTGCAAGTACTACAAATATTTTTGTTAGATGTTTCAATTTATTTCACCTCAACATCGACATTATAACAAATATAAATTTTTTTAATAAGTTATTGAATTTCAAAAGTTCAAGGTACTAATCACTTTCAACTAAAATAGCGCAACAAAACCATTCAATCAAAATGATTATTGATTGCGATATATTGTGTTCAATGATATTATTTAAGTGTATCCACAGAATTATACTACACAACCCCAAGTCTGGTACCAGCAGACTTGGGGTTATTTATGTGTGTAGGATCATTTTTTATTTTTCCATTTCAGTTCTAACCAAAGTCGAAAAATAATTAGTAAGCCACCTGTAATAAGTGTCATCATCCCTTCTTGCCACCACATCATTACACTACACCTCCGTTCGACTAAAGTATCATACTGAAGGATGACCTACACCTATTCTAACATAAAAACAGAACATATGTTCGTATTTTGGCAGCAGATTTTACATATTATTCGTTAATTCACCAACAACACTTTATCTTTGGTATAATTAAAGATAATATATAGGCATACAATTTTTTTAAAGAGAGGTTAAGCAATAATGAATCCTTTAGCCCAAAGCTTAAATGAACAACTTCAACAGTCAAATGCAACTGCCTTTACAATGTTATCTGACTTAGGTCAAAATATGTTTTATCCAAAAGGCATTTTATCTCAATCTGCTGAAGCAAAGAGTACAACATATAATGCAACTATAGGTATGGCGACAAACAAAGACGGAAAAATGTTTGCATCATCTTTAGATGCAATGTTTAATGATTTAACTCCAGATGAAATATTCCCTTATGCGCCACCACAAGGCATCGAAGAATTACGTGATTTATGGCAACAAAAAATGTTGCGTGACAATCCAGAGCTATCAATCGACAACATGTCACTACCAATTGTTACGAATGCATTAACACATGGTTTATCTTTAGTTGGCGATTTATTTGTAAATCAAGGTGACACTATCTTGTTACCAGAGCATAATTGGGGTAATTACAAACTTGTTTTCAATACGAGAAATGGTGCAAACCTTCAAACATATCCTATCTTTGATAAAGACGGGCATTATACTACTGATTCACTTGTAGAAGCTTTACAATCATACAATAAAGATAAAGTCATTATGATTTTAAATTATCCTAATAATCCGACAGGTTACACACCTACGCATAAAGAAGTGACTACCATCGTCGATGCAATTAAAGCATTAGCTGATAAAGGTACAAAAGTTATAGCTGTTGTGGATGACGCATACTATGGTTTATTCTATGAAGATGTGTATACTCAATCATTATTTACTGCATTATCTAATTTAAATTCAAATGCAATATTACCTGTTCGTTTAGATGGTGCAACAAAAGAATTTTTCGCATGGGGATTCCGTGTTGGGTTTATGACATTTGGAACGTCTGATCAAACAACTAAAGAAGTATTAGAAGCCAAAGTAAAAGGTCTTATACGAAGTAACATTTCTAGTGGACCTCTTCCAACACAAAGCGCTGTTAAGCATGTATTAAAAAATAATAAACAATTCGATAAAGAAATCGAACAAAATATTCAAACATTAAAAGAACGCTATGAAGTCACTAAGGAAGTTGTCTATGCTGATCAATATCATTCACATTGGCAAGCCTATGACTTTAACTCTGGATACTTTATGGCAATAAAAGTTCATGATGTTGACCCTGAAGAACTTCGTAAACATTTAATTGAAAAATATTCAATTGGTGTTATTGCACTTAATGCAACAGATATTCGTATTGCGTTTAGCTGTGTAGAAAAAGAAGATATCCCACATGTATTTGATTCAATTGCTAAAGCGATTGATGACTTAAGATAATTAATTTCAACCAATAATCTGATGAGTATGACTCGGATTATTGGTTTTTTATTTTTAAAATTATTCCTTCTTTCAAAGTATCATAAGATATATTTTATTCAGCAACTTGTCAAACACTATACCTAATTAGTTTTATACATCTCTCCTAACAAAATTTAATTTATTTGGTACAAATTTATATAACTTTTGGCAAATCACTTCAAACATTCAAGCATCACATCTCTACAAATGTAAAAGGCACCCCACGATTGTGAGATGCCTTATTATAAAATTAAAGATTAGAATTTAAGTTCAATATCTACCTTTTTAATGTCAGTTGCTTTAAATACTCTTTCATCTTTATACTCAGTTTTTAAGTCTACATATTTTGACGAACCATTTTTAAAATACACTTTATACACTGCGCGTTCAGCAAGTCCTATGTCATGTTTAGTTATCCCTTGATCATTTGCCATTGCTGATTTAAGTTTTATACTTAAATCATTAATTGTAATTTTGCTTGCATTATAGAACACAAATTCATTTGAAACTATGTTTTCAAATTTATTTATTGTTACTGGGAATTTCACATTATTAGATTTATTTATTTTTTTTTTGATTTAGTGTATTGTTTTACATCAATATCAATCTTTTTAATATCTTTGGCACTAAATAAATTAGGTGTAAAGATGTCTGATTTTAAATTCACTACTTGTTTCTTTCCATTTTTGAAATATACTGTATATTTTGCTTGTTTCGCAAATTTTAAGTCAAGATCACTGATACCTCTTTCACTTTTTAATACAGATTTCACTTTGTCGTTTAAATATTTGTAACTAATTAATTGTTTATTCGAAATTTTTAGTTTTGATAAAATTGGTGTTGATGTGCCATTTACTGCAATTGTGTATGGTACATATCTGTCTGCTTTCGCTTTAGTTCCTGTTTTAACAGTAATTTCAATTCTCTTAACATCTTTCGCATGAACTAAGTTTGCTGTGTAATTTTTTGAATTTAACTGTAAGATTCTTTTACCACCATTTTTAAAATAAACAGTATAATAAGCTTTCTTAGCATATTTTAAATCTTGTTCACTAATACCTCTATCATGCTTCAGTACTGATTTTATTTGACTAGTTAAATTTTTGTAATTTGTCCAAGGTTTATTTGAAAATGAAAGATTCGATAAAATGTTTGTAGATGTACCATTTAGATTAATTGAATATGGAACTTGATAGTTTCTTTTAGCTTTATTTTCGATATGTTTTTTTGTATCTACGTTAATATTGATACTTTTAATATCACTTGAATTGATTAAATTCGCTGTGTAAATACCTGATTTCAAATCGATAACTTTCTTCGTTCCATTTTTAAAATTAACTGTATATTTCGCTTGCTTCGAAAGTCTTAAATCAACATCAGTAATACCTCTATTTGATTCTAAAACTGATTTAACTTTACCCTCTAAATCTTTGTAACTAATATTTTGATTTTTATTAAATGTTAGGTTTGATAAAATGTTTTGGCTTGTGCCGTTCACTGTGATTGTATATGGCACTTGAACATTTGCTTTAGCTTTATCTTTAGGTTGCTTTTTAGTATCTACGTTAACACTGATAGCTTTAATGTCACTTGTATTGATTAAGTCAGCTGTGTAGATACCTGATTTCAAATCGATAACTCTTTTTGTTCCATTTTTAAAATGAACCGTATATTCCGCTTGCTTTGAAAGTCTTAAATCGATATCACTAATACCTCTATTAAAGTATAAAACTGATTTAACTTTATTCTCTATATCTTTATAACTAATATTTTGATTCTTATTAAATGTTAAGCTTGATAAAATGTTTTGGCTTGTACCGTTCACAGTAATTGTATATGGAATCTGGATGTTAGAATGTCCATGGTGTAATGTACTTGATGATTTATCTAATGGCTTAGCTGCGGCAGATGCTTCGTTAGTATTAAAGTTTGCTCCTGTTGATGCTATAACGCCTAATGCTAATGTTGTTGTAATCAATGACTTAAATTTCATAAATTATCTCTCCTTTTTTATGTAATTCGTGATTGCAACTTTATTATAGCCAGACTTTCTCTATTTTTTGAATTAACTGAATATTAATAATAAATTATCTTTAACAATAATTTTTTAACACTGTTAAAAGTTCTTTTAATTTTGATTAACTAACTAATTTACAATACCTAAAATGTTGTTTGATTTTGTTTATACCAAGTTTCAAACTTAAATGTCATAACAATCTTCATTTCTTAATTCCGATTATATTTGTCGATTATATTTACAGCATCTTTATACTCAAAAAACATTTACTTAAAAATATAAATTCGATTTAATAATTAATTTAAATTTAGTTAATCAATTTTGCATCTATTTTGTTGTAAGCTATATAAAAGGAGTGATAATGATGGTAAAAAAAACAAAATCCAATTCACTAAAAAAAGTTGCAACACTTGCATTAGCAAATTTATTATTAGTTGGTGCACTTACTGACAATAGTGCCAAAGCCGAATCTAAGAAAGATGATACTGATTTGAAGTTAGTTAGTCATAACGTTTATATGTTATCGACCGTTTTGTATCCAAACTGGAGACTTTTAACATAAAATTACTTATCATTCAAAAAGTAAAACAGCATAATATCAAGGTTTATAACTTTATCATTATCAATAATACCTCATATAAAATAAAATTTTAGGGACTTTTTAGGGACTTTAAATTTAAAATTACAAGTTTAATAGAAACATCAAAATAATCACATGTTTGTGTGGAATGTACACCCCAAAAGCTAGACTGAAAAATCTATTTTTTGAGGTGTATTTTTATAGGTAAATATAATAAATTAGAGTAGACAACTCAGAATTCCAATTTTATAATAATATTGCTTGACATATCAAACTAGATAGTACTATTTTGAATATATTATTATAATCAAAAATTCATTGTAAACTTTTAGACAAAAGGAAGTAATAAAAACGTGAAATTTAAAACAACTAAAGAATGTAAAAGTAATAATATCTTTAAAAGAAGTCAAGAAATTAATAATAGAGAAAGTGAAAAGGGTTGTTTATGGGGCATTAGCATGTTGATTCTACTTTTCTTATTGATTCTGTTTGGAATAACTGCTTGTTCATCAAGCATTCACTTTATTAATTAGATTTTTTTACTTGGAGGTATCATGTGAAGAACCATACAAATATAATTAATATCTTATTAGTTATAGTCAACTCATTAACTCATTTTCTAACTCTAAACACCTCATTTTTTAATAGTTCAGCATCGGATTTCTGTTTTATCATAGGGGCTATATTTTTCTTGATCGGAATTTTTGTTGCAATATACGGTATGAAGCGAGCAACATATTGGTTAAACTTATTGATTTTATTTACCAATATTTTTTATTTTCTACACTTCTGTGTTTTACTTTTGTTAAAATATATAGGATTTAAATTATTTATTTATTTATGAAGGGTGTGTATTGTTATTTACCTAATTTATAGTCTAATTGTCTATTTCATCTGCATTATAAATTTTTTCATAATGGCTGCACCATTCTTAATGACTAATGCTGATTATGTATGGACGCCTATGACTACAGTTACGTTATTTATTTTGAGTTTGATTATTTTCTTGATATTTATAAAAACAAAAGATGTCGTTCATTTAACAATTTTCATATTAAACTTACTTTTTTCAATACTTTATTGTTTGCCTATACTGTTTTATTTATGAACACTTTTATATTATCTAGAAAATTAAAACCACCCGTAAAAGGGTGGTTTTTTTAATATTTACTTTTTAGTGCTTCGTCAATTTCGTTATAAATCTTTTGAAGTTGATATTTTGCTTCTGACATTTTCTTAAAGTCTTTTGACTTAAGAGCATACATTGCTTTTAGACCTGAAATTTTTATAGTTCGCTTATAATAAGTGTTTAAACTTCCAGTAGCTAATTCATTAACATTTAGTTCATCTAATAACGATTTTAATTCATTAGCTAACTTTTCGTTTTGATATTCATTCGATGTTGGCAAGCTTGTGCTAGCTTGTGCCTCATTTTTATCTAGATTAGTTACTAGTGGTGATGCTAAAACGATTGCTAAAGTTCCCGCAAGTATAGATTTTCTAATTTTCATTTTTTATTCTCCTTAGTAATTAGTACTAATTTATTTTAATGACTAACTAAAAAAAAGTACATTAATTATTCATTAACTATATAGATCTTCTTATTAAATGAAAATTAATAAATTATCAAATTGACATACCTTATTGTATTTATAGAAAAACAAAAAAAGGTAAGCACCGAAATGCTTACCTACTTCCCATAAACAATATAACACATATACATTGATTTGGAAAGCGCAAAAATAAATTTAATAAACTAGCCCGAAAAGGAGCAATACATAAAAAATGAAAGGCGCTCCTTGAAAACGCCCAAGGTAATATTAACATAAAATGGCTACTATTGCATTATCTAATTTTATTTAATTAAAACAAATATATAGCACAAAAAAACTAGCCCGAAGGCTAGCTTATGAATAGATGAAAATTTGAACACATTGCTGTGTCTAAGATAAATATAACACATATTAATTACTATTAATAGAAAAATTATAGCGTTTTTTAGATCATTTCAATTTATCAAGACCAAATTCATCAAAACACTAATTGAACTTTAATTTTTAGTTAAAAATAATTAATCTTTTATTAATTTCAAGTTAATTAATATATTTCGTCGATTAGATTAAACTCATTTTAGGAATTTCGCAAAACTAACTATAAATTTAAATATAGAATTTAAGGAGAATTAACATCATTATGAAAAAGAAATTAGCAACAACAGTTTTAGCATTAAGTTTTTTAACGGCAGGAATCAGTACACACCATCATTCAGCGAAAGCTTTTACTTTTGAACCGTTTCCTACAAATGAAGAAATAGAATCAAATAAGAAAATGTTAGAGAAAGAAAAAGCTTATAAAGAATCATTTAAAAATAGTGGTCTTCCTACAACGCTAGGAAAATTAGATGAACGTTTGAGAAATTATTTAGAGAAAGGCACAAAAAATACTGCTCAATTTGAAAAAATGGTTATTTTAACTGAAAATAAAGGTTACTATACAGTATATCTGAATACACCACTTGCTGAAGATAGAAAAAATGTTGAGTTACTAGGTAAAATGTATAAAACATACTTCTTTAAAAAAGGAGAGTCTAAATCATCTTATGTAATTAATGGTCCTGGTAAAACTAATGAATATGCATACTAATAGTAGTTACATAAATTAAAAGGTAGATATTTCTTTTTTATATAAAGGTTTGGCAGACATTTCATAACTTGCCAAACCTTTATATATCTAATTATCAAACTGCACTAAACTTACCAAAACCGCTTATTCTATTACCTGCCTTGTCTACCTCTCCTGTCGCTATATAACGACGTTGTCCACTATTAGCAATATAAGTAATCCATCTATAGCCATTAATGCAATATGCGCCGTCATATTTGATCGTTGCGTTATTGGGTAATACACCTGTAATTCTTGAATTAGTTGAATAGCCATCCCTCACGTTATTACCTTTAACATTGGCAACTGTGTAATAACCAGTCTCTTTTTTATACGGTCATTGTTTTTATCGAGTGTATAACCTGCTGGCACTGGTGAATTCTTTTCATTTTTAGCTGGTGTTTTAACATTACTGATACCTGATACACACTTCCAATAAAAATAACCACACCATTTAAGATGCGGTGTAGCGACTGTAATATTTCTATGTTGTTGAGATATATTTATCGAGTGAAGGGCAAAAAGGGTATCAATTGCCAGGATAAGTGTTAGGTTACTAGGCCACTTAACAGGCTATATAGTTCACTCCTACTATATACAATTAATTATAACATAAAAAGCACCCCGTAAACTATTATACGGGAATGCTAAAGTCATATATACTACGGGGGAGTAGTATGAAAACTATGCTCTCTATCATAAGAAAAAACACCCAGTGACATGCTTGGGTGAACAAGGATGTAAATAGTTGATGCATGTGTAACACATCATAACAAAAAATTAACCGGAAGGCTAGCTATAACATACAATCTAAAAAGACGTCCTTTGAATACGTCTAGAAAGATTATAACATAAAAAAATAGGCAAGTACCGAAGTACCTGCCTAAAAAAGGATTATCCACTTTTTCATCCTAACTGATTTCTCCCCATAAGTCACCTAATATCTGATTAGGTGGGGAAGAACCATTCGTGCATGAATGAGAATTTGATGAAAGATAATTTTCACTACACATATTCAATCAAGACATTGCTTTCTATAATAAACAACTATTTTGTTTTATTTCTTTTCTATAACAACCTTTGTAATTAAGTTGAATCCAGGGTTTTTAATATGCTCTGATAAATCTGGGACAACAAAACCTTTTTCTGTTATAGGGAAAGACTTCGTTTCTTCTTTTTTCTTATTCTTATCATAATAAGTGACTTCGATCTTTGCGCTTGGATCTAATTCAACTACTCTAAACTCTTTATATGCTGTCGCATCTAATGCCCATTCGACATAGTATTCAATTTTTTCTTTTGTAAGTGTAGTCCCAGGTTTAATAGGAAACTCGACATAATGAGGGGATAGCAATTCATTTCCTTTACTATCAACTCCAGTCACATTTACCATCAAATACGGGCCTGTTGGTTCAAAATAACTCGCGTCATCGCCTTTTTTATATTTTCCTTTGTCGAATGAACTTGATGCACTTACCTCATTAGTAATTGAAGAAAATGAGAATAATAACAATAAAACAGTTAAAAATAATAAACTTCTTTTGAGCATGGCGCTTCCTCCAAATATAATATATTTGTTTTTATTCATCTCTTTTTATAGCTAACACACTTATTTAAGATGATAAATATCAACAACTTCATTTTATATTGAGAAAATATTAAAAATCAAGAAAATATTAAAATAAACTAAACTTACATTAAAAAATAATTAACAAATATTTAACATTTTAACCTAAGAATTAAAATGCTTCTTTCACAATCAATCTCTCATGCCATATCCACTCATTATGATTGTTCCAATAAATGCGACACCAACCATCTATAATTTCAAACACATATATTAATGTTCCAGGCGCGTATACAGCCTGTCCAACATCGAATCTATAGTTAGTACGATTATCACCGTATCTAGTGGCTGAAGTAGCACCTAAGCCGTCGATTTTCGCATTAAAATAAGCACCTTTTGACCATTTAAGGTTATAAGGTGCTTTACTTCCAACTGTTATTTTACTTGCAGATTTACCGACTGCTTTTTGAGCAGGTGGGTTAATTTTATTTGTGATCTTATTCATTAAGCCCTCACTTTTATACTTAGGTCTAATAAAGTGAGTACAGCCGTAATAATTATCCCAACGTAACTTTGCAGGCGTATTTGCGTTACCGTCATAGTTTTGTTCCAAAATTAAAAATTGATTTGTATTACCACCATTAAACACTAAACCAATATGACCGTATTGTTTATATATTCCTTTGGTAAATACAGCCACATCACCTATTTGTGGAACAAACGATGGTGTGTTTTCATATACTGTTGCCATGTTTTTAAAATCGTTATTGATTGCATCTTTTGCATTTCCCCACATTCTAATTTCTAACAACCAATAAATGTAATCAACTGCTAAATCTGCACATTGGTAACCATACCAACCGTCAAAATCAATATATCTACCTTGATACCAACGTAACCTTGCTCTTGCTTCACTGTATGTTTTCATTATTTTACCTCCTAGTATTTTCTTCTTGGTTCTTCATATTCTAAAGCTTGGTGGCTATCACCTATACCTTTAGTAGTCGGGTCTTGAATCACACCAGTTAATACTAAAAATCCTAATATAGCGTTTAAACCGTCTGTTAATTGCTCTGTATAAACTTGAATATCATACCCAATAGCTTTGGCGATGTTTTGAGCAAATAAAAAGATAGCTGACAATATCGCTACCCAAAATGATTTTTGTTTCATTCTAATTTTCCAATTAATCATATTCTTATCTCCTTTTATCCAAAATAAAAAGACGACTAATAAGCCGTCTATTTGATATTTATATTATGGTGTGTTAATTTATATATAGAAAAAGGGCAACATGCGCAAACATGTTACCCTAGTGAGCCCGTTAAAAAGACGGTGGCTATTTTAGATTAAAGATTAAATTAATAACCATTTAACCATCGAAACCAGCCAAAGTTAGCGATGGTTATTTTTTATTGCTTAATTCAATAAGCTTGATTACTAGACCTATCAATGCAATAAGGAATAAACCAAACTGCAACATGGTACTAATTGTAATCATTAGGCGTCTCCTTTCTAAAGATTTCAGTAATGCCACCATAGGCACCACCTCCTTATACTCAGATAGCCACCATCTATCCAACTTGCTCAAAGCATATTATAGCACATATACTTTTTTTACTGCTTGTATACTTTCAGATTATTCTCGCTTTGTTCAAAACTATCTATAGAAATTTTTTATAAAACTTACAAACAGCAGTAAAAAAGTGAATGTTTTAAGTATAGTAATAAAATAACTTATGGTACTTTTTATAGATTTTAAATTTTTTCAGCCAAAATTTCACTCAAGTTGTATATAAATATATATCAATATGCATATTTTTAGACTTAATCGTTTTATTATCTCTATATATCCTCAACTGTGTATCTGGATATTGTCCTTGAGCACCAAATAAATCATAACCAACCGAATCACCAGAAGAAGGGTGAAACTCAATTAATCCTCTTTGTATTTTTCCATTAAATGCATCTGTGTTATATAAATTATATGTTTCATGTAAATAATGTCTTGACTGAAGGTCTAGCTCCTGAACAGTTACTTCTTTTTTATTAGTTTTAACCGTTCCCAAAGGTACTGTATTTTGTTTACCATCTATCCATAAGTTAATCGGTACTTTCTTTTCTTCCTCCAATTGATTATTATCATGTAACGTTACACCGCCATACATACAAGCTGTTTTGAATGGTGTACCCCCAGTACATTGATAACCATAATAAACACCATATAAATCCACTTTTTTCCCTTTGTATATATTGGCGGTGTCTTTTGAACCAAGGTCTACTAATAAATCATTATACCATTGATGACCTGTAAAAAAATCATTAAACAATATAGTGTTCTTTAAAAATTGATCATTACTCTCTTTATTTTCAATTATAGCACTTCCATTATGATAATAGGTTTGTCTAAGATTGCTTAAAGCAGTTCCCTGCAATTCAGACTTTTTTTGTAAATCTTTTCCATTTATTTCTTCGCTTTTCTCGCTACAATTTACAAATGGACTTGTTATCAACGTTAGGGCAATAAATGAAAGTAGTATAAATGTTGTTTTTTTTATTTTACTCACCTCTAAAGCATAATTCCATATAAACTTGTTATTATCCGAAATTTTTGTATAATAGATTATTTTTGTTGGAGTAATTATTAGTTATATACAATAATTATGGAATGATCATTATTTACTTATACATACATATATTACTATACCTTTTTTATACTTGTCTATAATATAATAAAAAGATTTCATTTTTACTCTATTATACATTTCAGATATCTTACTTACTTGGTATTGACAACACTTCCCAACTTCACTTGCAGTATGCTTCCTGTCTTTTGAGCTGTGTAATACCATGTACGTACCTCTTTTCAATCAAAATAAAAAGCCAGTGCCGATGCACTGACCAAAAACATTATTTACATTTACGACCATACAAATAACATGATAACCATCTTGCCCAACTCATTATGTCCACCTCCCTTAAGGTAATAACGCAGTAATTGATGCAGTAATGACTGCAATCATAACAATTGTTACAAGCGCCCATATGGCACCTACGAGCCATTTATTTTGGGCGAGTGTCTTTTCTTCATTTTTTTGCGCAACATCTACTTGCGTTTGATATCTTTCTTCAATTCTGTTTAATATCTTTGTTTGCTCTAAATTCTCATCTACAACTTTATCTTGCTTATCTTTAAGTTCTTTATGAGATTCTCTTAGTTCATTATGATGTTGCTTATGTTCCTCTCTAAGTTCAAGCACATGATCAGCTGTTTCGTTTGCTAGTATTTCAACATCATCAACACGTTCAACTAATTCAGAAAGCTCTTTTTTTATTTTCTGAATATCATCCAAAACTACACCTACTTTCTAAGAAAGCTATGAGCGTAATGCTCATAACTTAGTATAGTTACATTGTTTCGCTATCAACTGATTTATCAGATGACAAGTCAGTTCTATCCACAACTTCTTTCACAACTTTCACACCGTTTTGATTGCCTGTTAATTGATATAAAAGATTTAAAGTTTCAGCAATCTTTTTAGCGTTTTCCTCAGATTTAAAATCTTGTGCATAACTTGCTGAATCGGACGTTGTAAAACTGCCTACAAAATCTTGATACAAAACGCGCTCTGTTCCCTCTTTGTCAATTTGTACTAAAATAAATCTCTCTGTTTTTTTGATAATTTCATTTGCCATATTAAATGACCTCCTTAAATTTTTGTATAAAAATAGTGCCAAGGATTACTCTTCCTCAGCACTTTTGCTTTTTTCATTTTGTTCTTGTATATATGCTTTTAACATTGCATTTTCTTGTGTTAGTCTTGTGATTTCTTGCGATAAATAGTGAATTGTATATTGTGGATTGGCTTGTAAACCTTGATTGCTATCATTCATTTATTAATTCCTCCAGTTTTTCGATTTTTGATTGCTGGTTTTTAATAATAGGTATTAAATGAACCCAAAGTCTATCGTATGCGATACCTTCGATTTCTCCGTTGTCATCATAAATAACAAATTCATTAAATCCTAATTCTTCAACCTCTTCCGCTATTAAGCCAGTATGTCGACTAAGTTTAAAAGTATCATCAGATAACTTTTTACCACTTTCCAATTCTTTAGCCATTATTTCCGATTCATATTTGTCAAACCATGTACGAATTGGAAGCTTTAAAATCTCTTTTGAATGACTGAACTGATCGTCTTCATTGATGTATTGGTTTTCGATTGAAATTTTATACTTTTTGGCAGAAGTAGCACGCCCAATTGTTCCAGCAGAAGTAATGTGTAAGTTAGCAGGTGCTGAATAAGTACGCTTATAAATAGAATTAGAAGCGACTCTATCGCCAGCATTATCAGAACCTACCGCCAATAAATCATAACTTTGAATGCTAACGTAACTATTTCCATCTCTTCGTTTAACTAAGTTGAATTTGCCCATACCTGATTCAATTGTAGTGTCTCCGCCTGTAGCATAGTCACCATTAACGACTTGAACCAATCCTTTATTGCTACGTTTAGAAAATCTTAATCCAGCACCGTACTTATAGTTTTCATCTGAACCAAACATGATATAACCGTCAGTTTCGTATGCACTATCAGCGTTTGATAATGTGAATGCGAATCGGTTTAAACCAGGTTTATTTTTGGTGTTCGGAGATAAATATATCGGCGCTTCTCTACTTTCAATATTAGCTGAAGCATATGAATCGATAATAATTCGATTGTAGTCAGATGTTAAAGCGACTACACCGCCATAAGAATTGATTGTTATGCCATTCATACCACTATCACTGTAAGTTTTATCCCACCATTGAATAGTACCGGATGAACCTCCGTCTTCGCCTTCTCCATCAATATATGTTGAAATACCAAAATGTGACATATAAAGTGAACCGCCTGCGGTATTATTTCTAAACCTTAGATGTCCATCTTTAAGACGTGTGAATATATCATCGGTTGATCGTTTGCCTTTCCAAGTTCGTTGTACGATTCCGCCAAGTTCAATAAAATCATTTTGAACTTGTACATAACGGTTAGCATTTCCGCCTTTAATACCAATTCTATTCACATTGATGTCAAGACCTTCATTTGATAAGTTTAGGCTATTAACAATGTCATTTTTACCAACTTTGTTATTAATATTATTTGCGACTACATTAAATTCTCTATTCGCTGTTATATCAACTTTATCGCCACTAATTTTCACGCCATCTTTATCAATAGTATGTGAAGTAATCGCCCCATTTTCGTCATACCTTAAATAGATGCCTTTCATAGCATTTACAGTGATGTCTGCTAACAATCTTGATAGTGTTCTTTTAGAAGCATTAAACTCTTCTTTAGTAGTTCTTAATTTGATTTCCTTACCATTTTGTATAATTTGAGAACCATAGCGAGTCAATGTTTTCCTCTGTGCATCTGTGCTTTCTTTGACCTTGTTGTCTGTATAAGCATTAGCTTTCTTTTCAGCGTTTCTAGCCTTTAGTTCTGCGTTTTGTTTTGCCTCTTCAAGTTTAGCTTGAGCATCTTGTATAGCGCGTTGCTCTTCTTCCGAAATTTTACCATCAGCATACGCTTGCGATTCCTTCTCTTTAAGATCATCTTGAGCATCAATGTATGATTTTAAAGCTTCTTGCGCTTCTTGATTTGCTTGTTCAATACTTGCTTTAATCTCAGGATTATTGGACAAATCACTTAACTGGTCATCAGTATATTGTTTTTGTTCTTCCAATCCGTTTCGATATTCGTTTAACGTAACTTTATCTTTGATTTCACCTTTTAAAGTCGTTCTCTCAGCTTCAGCAGTATCTAAACGTTCAACAATACCGTCTTTGTCTGTTTTATAGTCCGATGTTTTTACATAGTCACGTAATTGTTCTTTTGTGGATTCTCTAGCTGCTTCAATAGCTGATTTAACAACATTAGGTTCTCCGACTAACTGCAAATCTTCATTCACCGTTAAACCAAATTTTGTTGCTATTATTTCCAACGCTTCTTTATATTTTTCATCAGTGTATTGTGACTGTAATAATTTAAATCTATCTGAAATGGCGATTTTGACATCTTCTACATCTGTATAAACATCTTGTAATTTCTTTCTATACTCAAGAAATAAAGCTTGTGTATCTACCAACCGACCAATCGTTGCAGTTTCGGGTGTCATAGATTCTAAATTATTTTTAATTTGATTATAAACATCAATCACAGCGTCTAAACTTGCTTGTAAGTCCGCTTTCAAATCATTATCTACTAAGTACTCGCTATTCAGTAATTCTGTAGCTTCTGACAAAAGACTAGCGTGTTGTATAGATAAATTAATAAAAATATTGTTTAATTCACTGAATAGCGCTTTCTCTCTTGTTATACCACCTAATTTTTCAACATCATTTGGTGTTGCTTCAATCCATCGACCATTCCAATATCTACGCAAGACAGCAACATCAGGGTTACTTGTATCATACCAAAGCATATCATTGACTGGATTTTCTGGCGGTGTATCACTTTTGTGTATTTTGCGTTCAAAGTATTCTAATTCACCATCTACAACATCTTTAACTATAGTGTTGATATTGCTAATATTGTCGTTTAATTTTTGGTGTATTAGGTTTAATCGCTTGTTAAACTCTTCTCGTAATTCTGATTCTTTGAACTCTTTAGGTTGACCGAATGTATATGTGCTATTTTCTGAAATTATGTTATATTCTTCAGCAATAACTTCTGCCTCTACATACAATGGCGGGTTAAAATCTCTATGTTTTACTCTGACTGTATCGCCAATTGATATAATCTCGTGCGGATACGTAACTTCCAAATCAGTAGAAGTAATCTCATATGACATAACTGCCGACTTACGTTTATTTAACTCTGTTTTGGCTAAAGAACTTAATCGTGTTTCATTCATATTTTGATCATCTGATTGTGGTTCATATATCCCCCAAATATAGCGCATAGGTAGGTTGAATTGACTTTGCGCTTCGTCATCTGTCACAACTAGCTCTAAACGCTTCCCTTTGTCATTTTCAGGTCCCACAGCAATTAATGCTGTTTTGATTTCTGACATATCAATCTTCCTAGTTAACCCAACCAAATCTTTACCATACTCAATTTCTTTACCTTTGAATAAGCTGTTTTTCTTTTTGAGTACCACATATCTACCTTTGACGGTATTAGAACTAAGCTCTATATAAAAATCCAATACCATTTTATAGGTTGTACATAATTGCTTTAAAACTTCATATCTAGTTTGATAAGAAGTCCATGACGTAGTACGTAAGCCATCGTATTCGGTTTGTTCAGAAACTTCCCAACCTGTATCGCTCAACACATCTTTCAATGCTTCTGAAGTTGTCTTTTTCTCAAATTTGCCTGGTGCATACGGTTTAGCTGTTGTTATATCAGCAAGATAAGACGCTATACATTCTATCTCTGTGTAGCCGTCCATCGTATCTTGAACCCAGTTAATAATAAATTCACGCCATTGTTTGTTTGAATCCCTTATAATAACACGATGTCGTTCACGGAACTTTTCAGCTCTTTCTGATGATATGAGCAGTTCAAGCATTTCTGAATTGTCATTAACATTACGTTTATGAATCGCTCTAACTAAGGAAGGGTCATCAGTAGAAAGGAAATCTATAATCTTGTCGTTAAAATCTAAAACATGTATCACACTCTCATCTCCTTTCTATAAATATCTATCTTGCCATTTAACCGTCGTATCAAAGACGTTTTCAGGTTGTATGATTAATTCACTGTACCCAGAATCAACATTGAAATAATTACTTCCAAACGATTTCTCGCTCAACATTGGTTCCTCATTGATGACAACACTTTTTGCTTGCATATCTATTTTCACTAAATCACCTTTTTGTATAATGACATCCCTTGCGCCTTTCGGTTTCGGTAGAATCTCCGTATTGAATGAACCTAATCCATTCATCTCCATCCACTTATAACCGTTATACTTCGCACTATAGATAGCTATGATAGAAGCTGGACGCTGATAAAACTTACCGCCATCTATCCACTCTTTCTCATCCATATCAATAGGTTTACGTCTATCTGGGTCTTTAATGTGATCAAATTTCCAAGTTTTAATAGAAAATTTATTACCTACTCTTCTGAGCCGCATATAAACAACGATTCTGTCCAAGTTATACATTATCGGTTTATTCTGATAGTCGTATATCTTTTTGGGGTCTCCTTTTTGGTTATACAACGTAACAACAATATGTCCTATTTTTCTATCATGATATTTATTTTCATAACCAATAGAAGCAAGTAACTTACCATCACTATCATAAATATGTTGTGCTGTTCTTCCGGCACCTTTACCTTTTTGTTCAACAATACATTTATAGGTAATTTGAAAATCTGTCATCGCTTTAGGGAGCCCTCGTTTCGTGCCAGCACCAACCCAACCTTTTGCATCAGGAAAATTAGTTGCTTTATATCCTTCGCCAAGATTGGATATCACAAAGTCACCGCCGACCTTACCACCTAAGTCATTACTTGGAATATCTTCAGTAATCATCTTAGTCCAACCTTTGAAATCACGAAACTCACTATGATAAACAGGAGGCATGTAATCCTTAACTTCTTTGGTTACCTCATCATCACCAACCATAAAATAATCTTCATCATTTTTAGTAATCATAAAGTAACTAGATGGTTTAATTGCTCGGGCTTCAACAATTAAAGGAGTGTCAGCAGTCCCACTATTTACAACTGAAACTTGGTCTGAAATCGCAGTATTTTTATTTCCTGTTACTGAATATTTGTAAGGGTCTGTTAGTACTACTTTGATAGTGAACTTAACAGGTATTGCAAATTCTTTGTGCAGCTTTATTGGTCCTTCAAAATAAGCGTTCCAGTACCAATCTTTAGATTTGAATTGTAATTTAACTTGTTCCTCGTAGTTAAAAAACTTTACTAATTCATTCAAGACGTCATCATGTGTTTTAATGCCGTTGTGAGATAAATAGTCATTACGTACCACCAAAGGTATATCAAAACTATAAGATTCAAGCCTACGCCCTTTATATATAGACCCCGAACGTCCATCTACATTTTCTGTTTTTAAAACATAATTAAAAGAGGGTATTTCAAACCCTCTTTCGACATACAACCAAGGAATTGTTTTGTTGTTCACTTTAATAGTGTCTATCATTGAATAGCAATTCCTCCTTTTCTAAACTTTACTTTTGTTGATTCTTGCCTTTCTCGCTTTTCTATAGACGCGTTCACCTTTTTATCAAAAGCGTATTCGTCAATAATCGGCTGATAATCTTTATCTGCAATCACATCGTTAGATTGCGCTATCTTCAGTAATAAAGCTATTTGTTGTTGCTGTTGTTCAATCATTTTCAATAATAAGCTTGGGTCATCAAACCCATTTACACTAGATAATTGACTAGGTCGTTTATTCTTACTTGCGTTTTTCCCTCTAACTTCCGCAGCTGCATAATGTAACATCTTCATTGCATCATTTCTACGAGCTGGATCTGTTGGAATAACCCATTCTGGATGACCGTCTTCACCTAAGTTATACCAACCATCAAAAACTTTTCCGCCTGTAGCATATGCGTAATCACCCGCACGCTTAAATCCATCCCAACCGTAGCGTCTAACAATGTACTGCATTGCTGAAATACCTTGATGAACCGGATTATTAAAGTTAGTATATCCACGTTTAGCGTTTGCTCTAAAAGTTGAGCCGATGATTTGGAATAATCCTCTTGATGGGTCTCCTCTTTGAGCATTTATATCCCAGTTATTCACTGCATTTGACTGGTAGTTACTTTCACGTTTTGCAACGCGCATCATTTGGTCATGAATCCACTTACCTTTATAACGACCACCTAAAATACTTTGCGCTTGTCGGATTACTCGACTGGCATAAGTTGCGCCACTTCCAGAAGTAGCACCGCCACCACCTATTGATAATCTTCCTTTTTTCTTAGCATTCCTTAAATATGGTTCAGGGTCAAAATGTCGTCCATTTCTCCTCATTTCAAAATGTAAATGTGGTCCTGTACTAAATCCGGTATTACCAGTTAAACCAACAACATCACCGGGCTTTACCATCGTGCCACTAGGTGGTGATTTGCTAAAGTTTTTCAAATGCGCAAATAGCATATCGATAACGCCACTAGTAATTTTTACATAATTACCATAACCACCAGACATAAATGGCATTCTTGTAAGTCTGCCACCCATCGGCGTTCTAACTTCTTGATATACAAATGGAAAATCGACACCTTCATGAAATGGTCTTCCAGTTGCAGCGGTATAAGCTGCGGTACGTCCATAATGATAATTAATTTTGTCAGGGTCTAATATTCCGCCGACTAAATCGCCACCGCCCATAGCTTCTAAATTTTCTTTTATCCAATCAGTAGCACTTTTCTTAATCTTAGACCATGCAGCTTTTGTTATGTCGCCTGCAATTCCCATACCTTTAGTTAAAGAATTGAAATCAATTCCAAAAGCTTCAAGTATATAATTTAAAAGTTTGCCTGGATTTTCAATAAAATCTAAAACATCGCCAACTTTATCGCCAAGCCATTTGGTACCTTTACCTATTTGATCTTTTGTCCAGTTAAATGCCGATGATGCACCGGATTTAATATCTTTCCACATAGTACCTATGCTAAATCTTGGAAGCGTTCCATTTAACATTGAATAAGTTTGTGCGCCGTTATATACTTTTGAACCTTTAGGTAAGTACGCTGTCGTATCTGTATTAGGCGTAAGTACCCGTTTGCCATTAGGGAATTCAATCATTTCATTTCTGAAACCATTCGGACCATTTCCACGTCCTTTATCCCCAACCGTAGCGAACGTATCCCGCGCAATCTTACCGTTCTTAACTAATCTTGTAGTAGTATGCGTATGTTCAGTACCAGTGTGTAACTTCGGTATTTTGTCCATACCCAACTTACCACCGACCCAGTTTAAACCTTCAATTAATTTATTAAGACCTCTTTTAACAGCGTCTACCATACCACCGATATGATCTTTAATTTTACCAATGATAGATTTTAAACCGTCACGCATGCTTCCAAAGATGTTACGCACTCTATCCCATAAGCGACCAGCTATACCTACAGTGTTATCTTTAATAGAGTTCCAGATGTTTGACATCCAATTTCTTAATTTAATAAATATATCTTTCGTCGCATTCCATAAACTTGTGAATTTAGACCTTACACCCGTAAATAACGAATGAGCCTTGCCGACGGTATTGCTTTTGATATTATTCCACGTACTAGATAACCAGTTTTTCATATTAGTGAAAATAGATTTAACACTATTGAATAAGAAACCAAAAATACTTTTTGTTGCATTCCAAATTGCCGATAATGATTTCTTGAAAACGCCTATTATAGCAACCCATATAATAGTTATTAAACCTTTTAGCAATCCGCCAAAGTACCTAACAACGCCAAGTATTTTGCCTACAAACCATAATTGAATTAAATTCCAAATTAACTGCACAGTACCTTTCAGTATCATTACAATGCCGTCCCAAACGCCTCGCCAGTTTCCTGTGAAAAGACTAGAGAACACTTTGATAATACCCAAAATAATATTAATAGCCCCTTGTATTACACCTTTGATATTTTCCCAAGTGCTGACAATCAAGGCTTTAACCGCCGGCCAAATAAATTGCATCACTTGCCAGATTGCGAACATAATTGGTTTAATTACAAAATTTAAAATAAATTCAAATATCGCTTTAATAAAGTTGCATATATTTTGAAGTGCTTGAACAATGGAAATTCCATTTTCATTAAAGAATCCATTGATTTGACTCCAAATATCTTTAGCAAAATCAACTATTGCTGATATCGCTTGTTTAAAGATGTTTTTAACAGAATCAATGAAAGGTTGAATAAATTGAATAAAATTACTAAATGTTTGTTTAACACTTTCAATTGCACCATTAACAAAATTTCTAAATGTTTCAGATTTCTTATAAGCAATTGTAAATGCGACTGCTAAACCAGCCAATACACCTAATACAATGCCAATTGGACCAGTTAAAGCTGTGAAGACAGTTCCTAATATAGGTACTTTAGTCGATAAAAAACTAATCAATCCACCAGCCTTTGCAATACTAGCTAATAATGGAGCTAATACAGTTACTGCGTTGCCAACTGTGCTTATGAATGCACCTAATCCAAAAACTACAGGACCAATTGCAGCAGCAATACCACCGAATATAACAATCGACCTTTTAGATCCATCACTTAAACTTGAAAACCAATCAACTGCTACAGATAGCTTTTTGATTAATTCTTCCATGACTGGAGCAAACGCACTTTCAATAGAAGCCCATACATCAGCACCTACTAATTTAAGTTTATTCATTGCTACTTTAAATCTTTCGGAGCCACTTTCAGAATCTTTAAATGTCTGATTGACCGTTCCTTGCGAATCTTCGATAGTTTTTAAGAACTCTTGGTAACTAAAGCGACCGCCTTTAATAGCATCTGCTAAATCAGGACCTGCTTTTGCACCAAATGCTTCAATCGCTAAACTTGTTGCGCTAGCTATATCCGGTGTCCTTTCAATTTCTGCTAATGTCTTCTTAAATTCTTCTCTTGGGTCTTTACCCGCTTTACCCCAATTGGATATAGCTTTTTTCAAACCACTGAAGGCTATTTCAGTATTAACACCTGATTTCTCCCATTGAGAGAATAAAGCGATTGATTCTTTCATCTCAAAGCCCATAGCCCTCATTGGAGCACCGTATTTAGTAATGCTATCAGCTAATGTATCAACACTTATACCGCTAGCCTGTGCTGCTTTCGCTACCATATCAAGTACACTTTGATACTCATCAGCTTCAATACCTGCATCACCCATTGCACGCGTAATTAATTGAACGGCTTGTACGCCGTCAGAACCTGTTATGTGACTAAATTTCAAGAATGACTCTGTGGCACTCTCAAGTTCTTTGCCAGTGAAACCTAACCTTGTGTTAACTTCCCCTAAAACACCGCCTACAGTCTCAGCGTCTTCTGGAAAGTTGCCATAAACATCTTTAAATGAATTCTGCAACTTCTTAAGCTCTCCGCCGGTTGCTCCTGTTGCTTGGGTAACTGTATCTAAACCTTTATCAACTTCTGCAAAAGCTTTTCCTGATGCTGCTGCAATACCTAAAACAGGTGCAGTTACACCAATCATCAAACCTTTACCAATGGATTTTAAACCATCACCCATTTTTGTTAATTTAGGTCCCATACTTTCAAAAACTTTACTGGTTTTTCCCCAGCCACTTTCTGCCATTCTTTGAGCTTCAACTTGAGCTTTTTTGAACTCTTCAAACTCAGTTGTTGTTTTTTCTAGTTCTTTTTCTAAAAAATTCAGCTCATTTGCTTGTTTGTTATATTCTTGTCGTAATTTTTGAGCTTCCGCGCTGTTTTCGCCCTGTTCTTGAGATACCTTGCCATATTGCTTGGCTAAATCATCAACGTTTTTCTTATAACCTGTGATAGTTCCATCAAGTTCTTTAATCCTTTGTTTGTAACTATGAGTTGATTTTTCGGTATATTTGAAGTTGTTACCGGTTAACTTTAAGTCAGAATTTAAAGTTTTAAAGTTTCGTTTGATTTCTGCAAATGATCTATTTAAATTTGCTGCATCTAAATCCAAACCTATAGATAAACCTTTTATTCTTTCTCCCATTTTTTACCTCCTTTCTAAAAAAGTTCAAAAAAATAACCCTAACCAAACGGTTAAGGTTAAAACGCATCAATTAAAGCCTCTGCTTTTTCTTCAGAAATGTCATTGTTTTTATTTTGATATATGGAAAGTACATAATGAAATGGCATTTTTAAAACTTCGTTAGCGTCTTTACCATTTTCAATTAAGTCCATCATGAGAGTATCCATATTTTTCAACATTGCTTTATATGTTAAATCTTCAGGCTTTATTTCATGTTCTGGATAAAATTTCTAGTTTCCTCAGTTTGCTGACCTTGAGTAATGAAAATCACTTGTTCACGAAGTGCATTCATTCCATCAGGTGCATGCATACGTTCTTTTAGGTCTTTAACTGTGAATTGGTTATCGTAAATTTTTACAACCATATCCATCAATCTGTCAGCGATTTCTCTTGGTTTCATCGTGCTATTTTCGTCCTCAATATCATCGATTAAATCCATTGCTTCGTATACAATTTCAAATGAAATGAAGTGTGGTGTTAAGTACGTTTGTAATTTAATTTCATTTGCTTTCGGGTCTTCTACTAATTGAATAATGTTACGTTTTAATTTTGCCATTTTATAATACTCTCCTTATTTTCAAATAAAATAGAGGGGTTGCCCCCTCTTATGCTTCTACATTTATTGTTATAGTGTCACTCATATTACCAACTGTTGCTTTAACCGTAGCAATGCCTTGTGCTTCCGCAGTAACTTGACCATCACTATTGATTGATACAATATTCGTTTGATCTGTTGTGTATTTCAATAACTTACTTTGATTAGATGGCTCTACTACAACATTTAAATCGTATGTGTCGCCAACTTTAAGTGTTTTAATGCTATCTGGTATATTAACCGACTTTACCGCAGTTTCCGATGAAGCCGGTTTTGTTACAAAGTTTCTTCGTTACCCTCTGTCACGTTTCCAGTATATTCTTCGCCTAAAATTTTCTTTAAGAAAGCCTCTTCGCCTTTTTCACCGTCTCCATCATGATTTGTCATGTTAGCTGAATCAAAGATATACTTACGTACTGACTTTTTATTATCAACTAAAGGGAAAAGTGCCTCACCTTCAACCTCTTCACTTGAGAAATCCCAATCTTTCTCAGCCGTTTCTCCATCGATTTTAGGATTTGTAAACATAACTTTAGGTAATAAAACTGTTCTAAATGTACCGTCTCTACGCTCTTGTCTGAACCATACAGCTACGTAATTGTTTTGTTTACCTTGTTTCTCTTCGTAAACGCCATCTTCATCATAATCTTCATTAAAAACAATTTTGCGAATCTCTTTAGGGAACGCATGCATTTGTAATGAGATTTTACCTTCTCCGTCTGTATTCCCTGATTCAATTGGACCGCCATCAGCATAAGCTGTTTTTAGTTCTCCACCAGTTTCAACACCAATTTTTTGTAATCCTCTTGTTTTTGTAATATCACTATATTTTAATTCCGCGCCTTCTTTCGTTAATTTAGCGAAACCTAAACCAGTAATGTTAATATACGCCTTTGGCGCACTTGCATGTTTTACTGCCATTTAATTTTCCTCCTTATAAAAAATGCCCTCGTAAACGCGAGAGCTTCTATATGTTTTAAATTCTTCTATATATTCCGGTTTTCCATTTGAAACATTTCCCATTTTTAGTTCAGACCATAATAACTTTTGAATGCGATTAGATATCTTATTTCTTATGATTCTCGCATTATATTCATCATTGTACTTAACAAAAACATCTATTTGGACAATATAACTATATGCACACTCATCTCCGTCAGTATAAGTTGTAGGTATTGGGTCGTCGATATCGTCAATAACAATAAAAGGTACATCAGTATCTTTTACATTAGGGTATTTATTGAACTTAATATTATTGATATTTACGTGCTCTCTAATAATTCTGTCTTGACTAATCACTTCATGAACTTTGTACAAAATATCAATCACAATTTTTTCAACTCCCTTTTTAGCGTCTCAAAATACTTATTTTGCCCTTGTCTTATTGCTCTATTAACACCGCCCATAGCTTTAGGTTTGATAAATTTACCTGTTCCTTTTTGAACGTGTCCATATTCAATTAAATGTACGATTTTATAACGGTCTTTAGAACCTCGCCAATGAACAGTAATTGTACGTTTTCCGTTTATCCATTCAGGTTTACTAAAACTTACCTCATTAATTAATGCTCCCGTATCTTTTGAGGGCTTTAGTTGTTTTTTTACTTCTTCAACAATTACCTTAGCACCAGCTATTAACGCCTTATCTTGAACTTTTACCATCTCTTTTATGCCAAAACGTTTTTCTAATTCTCTTTCTAATGCTTTATCACCTATCACTTTCACACTCATGAACTATATCCTCCACGAATCATAATAAAGTCTTTATTATCCAAATCTGGTGATACTTGCTTTATATTCAAACGATTTTTGAAATATCTTGATTCAATTTCAAGATAATGTTCTTCACTGGGTAAATAATCACCTTGCGGATCACGAATATACAATTTAATGTCATTTTGGGTTCCGTTTGAGATAGCTTGTTCTAATTCACGTAACCAGACACCATCAATACTCGCCCAACAGCTATATAATAATTTTTCTTCTTTTTCTCCAGCTTCTGGACCATTATTTTCAGTATACTTATAAAAATGAACACGAGTATTTAAACGTTTAGTTGTAATTCTAGGTTTTTTAAACACTTTCTTCATCTTCTGATACCTCCATTAGAGATAACGAAAAATCTATTATTTCAGGTCTGTAATTATCGTTGAAGTGTTCTAATAAATCTTGATAAGCATATCTAGCGCGTATAAGTATCAATTCTTGACCTATTAAATTCTCTAATTCAAAAACTCCGCACTGATTTTTTATACGCTCGTACGACATTTTTAACAACTGCTTTAAGTACTCATCCTCTGAATTATGGTCAATCTTTTCAAGTGATTTAAATTTGACAAGCAAATCATCAATCGTCATTGTCTTCACCATTCAATAAGTCGACGATTTCACTTTTAACCATTGAACTAGACGCTTTTTTTTGTAATGATTCGCATAGTTCTAATAATTCTTGTTTTGTCAGCTTATCTAAAGGTACGATATAAACTTTGTCGTACTTATTTTTGATTTGATTTGTCAACAATTCAACACGAGGATTGTTATACCCTTCAGCTGGATACAACTCCCCTACTTTGTACTTGTGTTGATTGTGCTCTATGTCTTTAAAAGCTCTAACAACTTTAAATTTCACCATTTTATCACCTCATAAAATTTTATAGTGTTTCTTCGGTACCTTCTAAAGCTGGCTTATGTCCTTTTAAATCTAATTTCCAAACAGCAGCAACTTTATTATCTTTCGCTTTGCCGTAAGCAAATTGTTTTGCAGTGTATAAATCCATATCATCTAACGCAAGTGTTTCTTTAAATTTCTGAACATTAATACCACCAGCTAAATAACCATCATATAAACCTTTAACGTACGTTAAAACCTTACCTGCTTCTTGGACTGTAGACTCGATAACATTCAAATTAAATGGTAAAGCAGTAACATATACGCCATTTGCATTTAAATGTGTATACTGTGCTTGAACCTCAAAAGCATCGGACGGATTAACAACCATTGTTACATTACCTTTAACCGCTACTGATTTACCTTTCTCGTTAGTTGAGTGGTATTTAAACACTTGCGTCAATTCATTAACCGTAGCGCGCGGATTAGCAAATGTAAGCGTACCTTGTTCTTCTTTCTCTGGATAAGCACCCTCAGTTACCGATACACCTTTTTGTACTTGACGGTTTAAGCCGATTGGTTGGTCTTTACCAGTACCTTTTAAGAACGCAGTTTCAAGCGCCACTGCAAATGCTTCTTCGATTTGAACACGAACAAATCTTTCAATCCACGCAGGACCAAAATCATTTAAATCTTTTGGTAAAACAACAAACGCTGTCAATTTATTTTGAATTGCTGTTTCTTCACTGAACGCAGCATCTAATTGACCTTTAATTTCACCATAGATTTTACCCCAAACGGCTACGCCAGAAGTTTCAGATTTTAAGAACTTCAAACGCAAACCAGCGTTTTTAATACCTAAATCAGCTAATAACGGATGATTCGTCGTCAAATCTTCAAAAATTCTATCAATTGTTTCTTCTGGCAAAAGTTTTTCTTCTTTATAGTTAACGTTTTTATTGATATCCATGAAGAAACTTCTTTGGTTTGCACTCAAAGATTGTGCTGATTTAGGTAAACTAGAAACTCTTTCAGCTTCTGCTTTTGCTTGTAATTTAGTTTCTTCAAATAGTTGGTTAATCATGTCACCGTACAATTCATTTTGTCTTTCTTGCGGTTCACCGTTGTTTACTGCATTAATAAATTCGTTTTTCGCATTTGCGAATGTTTCCGATAAATTTATAGTCATTTTATGACCTCCTATTTTTTGTATTAAAAAAGGAATCTTGAAAATCCATTTGCTGATACTTTACTATCTGCAACATCGATTTCTGATTCCTTTTCTTTCATATTTATTTTTTCAATTACTTTATTTGCTATTGCGTCAATATCAATGTTAACCTCTGGCGTTTTACTTACCAAAGCTGTTACACGATTTAATACATCTTTCGATAACACTTGTGTATTGCTTGCTACAATTTGCATATTGTCGTTTTCAAACATTTTACTATCCGCAAAACCTTGTTCAATGGCTTCATCAGCATTTAGCCACGTTTCCCTAGCCATCATTTCTACAAGTTCTTGTTTGTTTTTACCAGCTCTAACCGCATATGCCTCAGCCATTATTTGACCAACATGTTCTAATGTTTCTGCAGCATGATTTAGATCTTTCGCTTCTCCTTGCGCAATACTTGAAGGATTGTGAATCATCATTCTAGCAACCGGACTCATTTCGATGTGGTCACCAGCCATTGCGATAAGCGATGCCGCACTTGCTGCTATTGCTGTGATACGAACATTCACTTTGCCTTTATGAGCTCTTAAATGTGTATATATTTCACTACCAGCTACTAGGTTACCACCATTTGAGTTAATTATAATATCAACATCTTCATCACTAAATTCTAGTTGTGTTAAAACATCTTTAGGACAAGTCGAATCCATACCAAGCATTTCGTAAACCCATTTATCTTCGTTGGAAACGATGACGCCTTTAATCTCCGCTTTCATCTTCATCACCACCTTTCAAAGTGTTTTCATCTTTTTCTTTTTCATCATTTTCACCACTGTTAGCTTTTTCGTAGTTTTTAGTAATCAGGTATTCGTCTAATTCAGGATTGTCTGATGGTTCTTCACCTAACATAATCCGCACCTCATTCCTTGTAAATGAACCAGAACTTACAAGTTTGTCAATTGCTTCAGCATATTGAAGTGGGTCTTTTTTATTCACACCGACAATTTCTATTCTTGTATCTTTCAAATACATGCTTTGTGTTATGAGTTTCGCGTTTAATTCGTTCTGAATCTTTTTTAATAAAGGTGTTAAACAGAACTTCTCAAATACAAGCGTGTTTTTTTCCAAATCAGCTGTTTCTCCGTAAATCAAACCTGGAGGTATACCAATCATCAACGCAACATTTTTTATTGCATCTCTCATTAGCTCACTCAATTCAGAAAAAGGCATGTTACTATTCTTACCACCATTAGATAATTCCTCATAATCAAAACCTTCTATCAAAGGCGCGATTGCTAGTTGATTTTTATTAAAAGTATTGAATAATTTATTTGTGAACGCTTGTAATTTTTCTATATTCTTTTCGTCATATGCGCTAGAGGCAGATTTCAAAATCCCTCTTATTTGATAGTTTTTTAATTGTGCACCTATCATTCTTCCGAATATTTTCCCGTAATCTTCGAATAGACTTTCTACAAAGTGTGTCACTTTATTGTTGTTGTACTTTAAATATATGACCTCTTGCATTGTGAAAGTACGTTGATAAGTATAATCTTTAACCGTTACATCTTTGAATATATCATCATACAAAGCGTACTCTTCTCTGTAAAAGCTATCTGCGATAAGTAATTCTTTGCTGTCACTTACTACGATTAAAACCTCGTTATCATAAATTAGTTTATATATAACTTGTTGCCAAAAACTATCGCTTGATAAGTCAGTATTTGGTTTTATATTTAACTTGTAGTAAACATCATTCTTTTGAATTCTATTACCTTCCAATACTTTAAAATGACTTTGAGCGACAGCTCGCGCAACAAATTCAATACAACTATCAATCGCTAAACGTTTCACATACGCTTGTTGTGATAGATCTTCTATCATATCTAAATCAAGCATATATGTTATATCTTTCCTAGTTTTAAATATCTTTTCTAGAATACTCATGTCTCACCTCCTCTATTAGAAATCTATACTCATTAATGCATCAAGCGCTTTAGACATGTCTTTGTCTACTATATCGTCTGCTCTATATAATGCGTGAACAAAAGCCATGAACCCATCGGTTTTTCTTCTATTTTCATCTTTTTTAATATATTCTTTATTACCATCGGGTTTAACCTTTACTGCAACATTATTAGTAAACCAACGCATCAAAGGATTGTCTCCATATATTACGTTATGTTTCGCAAACATTGTATCGATACGTGGTGCAAGTAATCCATGTATTGCTTTTGGATTTCTAAGTACTTCAAGTTTTATGCCAGCATCCTCAAACGCACGTCTTACAATATCAGTTCTATAATTATCAGCTATGACTTTTTCAAGCCCATATTTTTCTCTAGCCTTTAAAAACCAATCAACTATATATTCAATTTCAATGACATCATCATCGACAATGGTCAATAATCCCATTTTTTCCCATTCTTTAATAGGAGGTTCTAATTTGACATCATCCAAAAACCCTTGTCTTACAAACGAATGTCCTAACCAAATGTAATCATCGTTTTTTCGGAATAATAGCCCTACACTTGCAAAATCTCGAATGTTTGCAAAGTCTAAACCACCAATACACATTTGATTATCTAAATTTGGTATCTCTCTATTAGTCGCTAGTATTTCTTTCCATGGTGCTATTACTTTTTCAAGGTCAACTTCAGGCAAATTCATTCGCTTAGTCATGAATTCGGGCTTATTTGAACGGTTGAATGGTAAATCGTTATATTCTTCTTCAATCGTGCTTAGCAGTGTTTTAGCGTATTCTGATAACGGTTTATGTAACATTGGGTTCGCCTTTTCCCACGTCTGTCTGTCATCAACTTCTTTTGGATCGTCTAACTTACAATAAAAAGCAAACAATCTACTATTTTTAACCTTGCCACTTAATACACTTGCAATTTTGTGCTTCATTGCATCGATATAACCCTCTCTAACAAAACCATCAGTACTTATATAAAACGTTCTTCTATTTTTCTTTTTACCTAATCCACCACGTTTGACGTTTACCATTTCAGGACCAAAGAAATAATGAATTTCATCAAAAATAACACACCCCTCACGTCCACCGTCTTTGGTTTTTGTGTTTGATGTGTTATATCGAATAACCGATTTAGTTGCACGGTTTATTATTTTTGCTTTACTAACTTCATAAGGAGCTTTTGGCGTTTTACCCGTCTTATTTCGTTTGTTATCCATTAAAACGGTTCTGATTTCATCAAACGATGTTTTTGCTTGATCTTCACTATTAGCAACAATGGAGATGTGATATTCTTTAACTCCGTGTAAGGGCGTAGAAAGAAAATCACTAATAGCACTTATTAGACCGTTTTTCCCGCCTCCACGTCCCATGAAAATAGCAAATTCTGTAAAGAAAGCTTCATCTGTATTTTTATCTATAAGAAATATATTAGCTATGATAAACCTTTGAAATGGTAATGTTGGAAAATACCATTTTTCAATAAATTTGATACAATCCTCGATTTTCTGTTCATCAAAATATACATCATCTCGTGAATATATATGTTTTTGTAGATAATTAAAGAGATCAATTCTTTCTTTATTTAAAATTATCTTTCCTTGTTTCCACAAATTTATATATTCATCAACGTATTTATTACTAATCATAGGTAATCATCAGATGGCGTTTCTGTGTCTTCTTTCTCTTCGGGCAATAAATCCGATAATTGTTTGATTATTTTTTGATATGCAGCATCTCTAGCATTAAATAGTTTGGCTACTGGTCTTTCCCTTTCATATGGTGGCGCCTTTTCAGATTGAGTAAATAAATCATAGTCACCTTTTTCTTTTATGTCTTCCCACATGTAATCAAGCATTACACGTAGCCTTGCTGCTTGAATAATTAAACCATCAACTACTTTTAATTTATTGCTAGGTATGTCTTTATATAATACTTGCAGCCTTTCTTTTTCTTTAAGCACTAAGTTTTCATCAACTATAATCTCCATTTCATCACCTGCCTTAAAATGGTTATAAGAGGGGGGGGTTATACATGGATTTTTAAAATTATCGCGAAGTCGAGCCCCTCCCCGTTCCCCAAGTATTTTGATCGCTTTTGATTTTTTTGACCCGGGGGTATTTACCATTTTTCGTCTTTCCATTTATTTTCTTTTTTTATAAATCTCTTTTCTTTTTTGTTGTGACATTTAATACACAGTGTTTCTAAATTGTTTAAGTCATGAGCAAACTCCGGATGATGTTCTAGCGATAATATATGATCTACATCCAACGACTTATGTTTGCTTTTGTCATATGTCGTTAACTTGCCGTCTCTCTTACATTGTTGACATTCATAATTATCTCTTTCTAGTACTCTTTTTCTTGTTGTTTGCCATTCTTTAGACTTATAGAATCGTATACGTTCGTCTTTAGTCATCATAATGTTTCACCTTATATAACTTAAGTAGTATCAAGACGCATCTATACTTGATGTGTAGTAATGTATTTACAATTAGTTTGAACATGTTCATACCTCATAAATAAAAAGACACATCACATAGTAATGCGCCTCTTGTTCATGCGTCGTATTAGCATTTAATAACCTTAAATATTAATCTGATACTAACATAATAAACTGTTTTAATGCGGACTTACATAGGGTAAAAGTCCGCTACACATAACCAATATACTTTGCTAACTTATCGATCAGTGCATTCCTTCTACGTAATATACTTGTCTTACTTGTACCAAAGTAATGTGCTATATCTTCCCATTCATAACAACCAATAGGACAATCCCAATATCTAAACCTTAATAACTCAAGCGTATCCTCATCACTTTCATCTATCAATCTATCTACACCGTTAACTATATTTCTTAATGTATTGTACCTGTTATCACTAAACTTCTTTATTGCACATCGTTCAATCGGATTACCCGGCAAATTACTTTTGCCAGCTCCCGCATTATCTGGTTCATGACTTTCAAGTAATTCATATTCTCGCATCTTCAACTCTCTTCGATAGTTATCGATGTGCTGAATGTATTCTTCAAGCTTTTTGATATCGTGTTTCTCAATCTTTATCATTCAATGCAATACCTCCGATAATATAAATTACTTTTTAATATCGTTATTTATTCGCTTCAATTCAATCCTGTATTCTTCTAACCCGTTGTATCCTTTAGTTTTAACTACTTCATCAAGTAGATAATCATTCATATATCTGAGTGCTTGTATCTCTCTTGCATGATCACTATTAATACTGATACAAACTAATAGCAATATAGCAAATACAATAGTCATAGTAATCCACATCACTCACTTACCTCCGCTCGAAAGACGTAATCACTCGGCGCCTCTACATCATCATTAGCTGTCATCATAATATATACTTGCTCAGTTACATACTTACCTAACTCGTACATTGCTAGTAAGAATAATAATCTTAGTATTTGCTTAATCATTTCCCACACTCCCTTATATTTTCAAACAACTGCCCTAATTTAATAACTGCACCTCTTTTAACTTGTGCCTCGTATTTGCGCTCAGCTTCTTCTTTACTCTCTGCCTCAACAACTGTAAACGTCTGATTATCTCTAGCAGTAGTAAAATGTTCATGTGGTTGTCCTGTTGAATCTTTGAATGTTGTGACTAAGTATTGTGTCATTCCTCATAGCTCCCTTGAACTTGTTTGAGCTTACTCATAAAAAACATTACTAAAAATGCTATTAAGATATGCGTCTTTTGATGTTTATAAGCAATTGTAGATATCATAAAGATAGTAGCAAGCATTAACATTTCATATATGTTTGTGTGTATAGTCTTTTTACTCTTAAGAAAAATAATTGCTATGCGATAAAAGAGATAAACGCCAAACCCTATTAAAAATATTTCTAACATGTCGCTCACTTCCCCAAAACCTCCTTGACTCGATCCAAGATGTCTTTACACGTATCCTTTTCCTGCGTCTGCTGTTCCATCTTGTCTTTCGTGGTTCCTTTTCATTTTCTTTTTGTATGCGTCAATGAGTTGGTCGATTGTATAGTAAGTATTGGCGTACAAAAAAGGCATTATTAAAACTTGTACAATACTATTATCAATACCTTTTACAAATTGTTCTGTTAGTGTATGCATTACATGAACAAAATAAACTGAATGTAGTTTAGGTAAAGTAACTTCATTTTCAATCAAATCAACCATAACCTCAGTAGTTTCTTCCAAATCTTCTTCATCAACAATAGTCAAAGTTAATTGCAAACTGAAAGCTAAGTAATCAGCAATCTCATCTAATTGTGTATCTAATGGCTTACCTGGTTGTTTCTTCCAATTTTTAAAAAACTCAAGTGTGTTAACCCACTCCGCAAATTCAATAATCATACTAGCTACTGTGTCATTTAAATTTCTAGTCGGTATTCTATCGTCGAACTTCTTTTGTATTTGTAATAACTCTTGTAACTGATCAATTGTTAATGTGTTAGTCATTTTCCTTGTTCCTCCTCATATTTATAGATAACTTGACCTGCCATAATTCCTACTGCTTCATCAAGTTCAATACCTTCTTTAACTGAATGTTGAATAGCATTTGTCATTCCATCAAGTATTTCATCAAATGCTCGCGCTTTCTTATACACGTCCTCAATCTCTTTTAGCAATCCCTCTGTGTCATTGCCGTTATACGCACTAGCACTTATAACGGATTGTTCAATTTGTTCACGATTATTCATCATTTCCATCTCCTCTAAAATAAAGTTAGTTGCTTCTGTTCCTCGTATTCCAAACCATGTTGCTTTATATATATTTCGAGCTCTTCAGCAGTATCAAATGTCTTTTTAACGCTTTGCCAACCTGGCACGATATGCCCGTGAAAGTAATAAGTGCCATTCACTACATGGATATGTGCCACTCGTTCGTTATCCTGATACAGATATCTCTTAGATCCGAAAAATTGGTTTAAGTATTCTTTGCGCGCGTTATATGTCATAGTCATTGCTCCCACAAGTCAAAAGCTCTTTGGACATAAAACTTCGCCTTTGCTAAATCCTCGTGTCCGTTTTTCAACGGTGCTCTAGATAGATATTTGATTGCATTACCTATTGCAAATGCTAATTGTGGTGGATACTGCGCCGTAACCTGTTCGATAAAATCTATAATTTCAATGTCGCCGTATGTGTAGTGCGCTGGTTGCTTAACATTGTCTTGTATTTCATTCATATCTACTTTTCTGTTACTGATTACACTCATTATGCTTCACTCCATTTCTTGAACATTTGGTTATAAGTATTATCAAACCAGTACGGATCACGTGAATGTTTCTGAGGTACATTAAACAAGTGTGGCTTCTTTCTTCTTAGCTCAGCCTCTCTCTTTCGCTTTCTTTCCAATTTGCGTTCGAGTCTAGCTTGTTCCAGTCTTTCTATTGTTTTCTTTTCTCTGTACTCGCTTAAACGCGTACCTTCTGGTGCGTCCATTGCTTCATGTAGTTCCCAACCGTCTTTTACTCTCTTAGAAACCATTCCAGCGGTTATACCGTGACTTTCTATTAATTCCATTTCAAATTTACTGAACCTATAAGGTTTATCATTTATTGTTACAATCCTTGCTTTTCTCGCCATTTTATCCACCTCTTATATTTCTTCTATTCGTATGATTATTTTGGGCTCAATTCCATAACGCTTTGAGCTAGTTATTTCTGTAATTTGGTTATCGTCTTTCCATACATGGCCATTACAAGCATCTAATACCGTTTTAATTAAGTTGTCGATATCCGGCTTAGTCACTTTATACTGCCCAACCATTTCGCTTTTCTTTTTCTTCGACCATGATTTAAGCAATGGAAAGTAAAAGTCTAATTCGATTTTTAGTGCGCGCTCTAGATTTAACTTAGGCATTTGCCCTTGTATATACGCTTTATGCTTTGTGTAAGACGTTGGCATGTAAGTTTGAACAAATCTACCTGTATTACGAAAGCGTGGACGAGGCGACCCCATCGGCGCATTAAACACTTCATTAAATTTAATTTCTATCTCCATGTAATCCCTCATATATATTCAAATAAGCTTGTTTGGTGTCCTAACTCCATTTGTTCATTATCAATAAGTGTATTTAATTCATAATCGTCTAAATACCAACGACGACCATTAAATTTTGTTTCTTTTATTCCAACAACTAAATGCCGACCATCTTTAAAATGTGGTGTAACTGAAAACATTTTGTTGCCGTCATGATCAAATAGATAGTATTTATCAAATGCATCCATTTTCAATCACTCCCATTTGCTATTTAGACGCTTAATAAAAGCTTCTCTGTCTTTCTCAAGGTTTTCATCTACTTCCGGCGTTTTCGTTTCTCTCGTGCTGTCTGTGAGCCATTTGGGTGTTTTTTCTTTTGATTGTTTAACGAAAGGTTTATAATTTTGTTTTTTGCTTTCAAGTTGTTGCTTTTCAAATGCACGTACTTGTTCAATAGATTTCAAGTTTGCATTAAGCCATGTATTCAAAATGCTTTTAGCATATCCCCAAGTAACTTTGTTTCTGTCTTTAGCGATTTTAAGTGATGCGGTAACTATTTCATCTGAATCATTTTCAAATGAATCAAGATAATAATTTAAATCGTCTAAATTGTAAGAAGTTATGAAACCGAATCCGTTATCTTGGAAGAAGTCGAAGGCGGTTGTCTTCTTCTTCTCATTATTCACATTCTTTTCATTATTATCTTTATTATCATTATTGTTTGTGTTGGTTTGATGTTGTTTTGATGTTGGGTTGATGTTTGACTGATGTTGTTTTGATGTTGGTTTGATGTCGTTTTGATGTTGGTTCCTGCCCTGCTCACTTTGATAAAAGTCATAATTGACAATGGTTATAAGGGTATATTTTGATGTTGTTTTGACTTCTAACATTCCATCACTCTCGAGTAAGTCAAGGAAGGTTTTCACTTTAAATCGTGACCAGTTAAAAAGGTCAGACAAGGTCAAAATCGATGTTAATCTTTGTCCTCTTTCTACGGTTACAATTTGGTTTCCAATAGGCACTTTTGCCTTTGAATGATTCGCTTCCATGAGTAAATATATCCATGCTTCAAACTTTGAAAATGTTCTCTTTTCTTTAAATAGCCAATGATTTTGAATTGAGCGATCAATACTTATCCAACCAGTCATATACACACCTCACTTTCAAACCGGTTAAATTAGAATGGTAAATCATTGTCATCTATTTCAATCGGACCATTTGCATTCGCAAACGGATTATCTTTTACTGGTTTGTTATTTGAATATTGCGATTGTCCACGTGTTTGTTGTACTTGTTGTTGATATAAATCTTGTTGAGTGTCATTTGAGTTTTTCGGTTCTAAAAATTGAATACTATCAGCAATAACTTCCGTAACGTATACACGTTGACCTTCCTTATTTTCATAGTTCCGCGTTTGTAACCTACCATCTACGCCCGCCAACGATCCTTTAGATAGGTATTTATTAACGTTCTCTGCTTGTTTTTTAAATACGATGATATTAATAAAGTCTGCCTCGCGCTCTCCTTGTGCATTCGTAAATGTGCGGTTAACTGCTAATGTGAATGATGCTACATTTACACCACTTTGAGTGGTTCTTAATTCTGGGTCTCTAGTTAAACGACCAACTAATATTGTTCTGTTTAGCATTTATAAACCTCCAACATAAACGGGCGCGCCCGTCACTTTTTGTATTTCACTTTTAATGTATTTTGCATTTGAATTTTGACTACTTAAATGAATTAAATGTATTTCTTCGAGTCTAGTTAAATCATTTGCTTTCAACATTCCGATAGCATGTTCTAAGCTAAAATGAGACTCCATAATTCTGTTTGCTAATGCGCTGTGTACACTGCCGTTTTTTATGTTTTCTTGCATTTGTTCATAGATATAATTAACTTCTAACATCATGTGCGTAATGCCGTTAAATTTGTATTTCAGATACTTCGTATCAGTAACATACAGGACCTTATAACCTAATGTGCTTTGTAATAAGAAAGCCACAGGCTCGTTAGCATCATGTTCAATGTCAAATGGTAAAATTGACCACGTACCAATTCGTAGCTCTTGCTTTGCCTTAATCGTGCATAAGCGATGACTTTCAAAATCCATAGCTCGTTGTGTTCCAGCAGTCATATAGCTGATTACACCATTGTCGACAAACTGCTTTGTGTACTTTGCATGATCACCATGTTCGTGTGTGATAAGACACCCTGCTATATGTCTTGTTTTATATTTGAAATGCTTTTGAACACGTTCAAATTTTATTCCTGCCTCAAGCAGTAACGTAGTACGTCCATCATTTAAGACGTAGCAGTTACCACTTGAACCAGTTGCTATTGTTTCAATTAAAATGGCTCTTCTTCGCTTTCTTTTTCTGTTGCAGGTTCTTTTATTTCTTCAAAGTCAGATACATCAATAGGTTTTTCATTTTCTAATTCTGTGTATTGTGCTTCTTCAAAAACTGGTGGTTCAAAATCCAATTGTTCTTGATTTGCATTTTCTTCAACTTCTGCATCCAATACTTCTTTGCGTTGACGTTGTTCAGATTCTTTAATTTGATTTGATAAAAGACTAGCGTCATCCGTGCTGTTTAAAATCTTTTTACATGCACGGTTTATTACAGTCTTTTTAGCCATTTCTTGAGGGAATCTTCTGTGTGTACCGTCTTCTTTAAATACACCGTTATAAACCATTTGTGATTGCTTCCACGCTTCTTCAATCTCTTCAAATGTCATGATTTCAGTGTAATTTCTACTTTCATCTTTAAATACAACTGTTGCATATGCACCGATAATGTTTTGTGTGTTTCTGTTACCAAAAGACTGTGTATGTTCAAGTTCAACAATTTTTCCGTTTTTAGTTTTATACTTAACTTCGTCACCTTCAAATATGACTTCTGCATTAATTTCTTCTGCGCCTGCTACACGTTTAGTTACTGCCATTGTTCCGTGGTAACTTCTTTGGAATTGAACCTTATCGCCATACATAATGAAATAGCCTTGATTCTTAGCAGGATTTAAACCTTGTACAACCATGTCCATTAAGGCGTTTGCTATGCTGGTTGAAGTTGCAAATTCCAGCGCTGGTTTATAACCATCTTTTTTAGATCCTTTTAATTCTTGCAGTTGTAACATTGCTGACTTCATTGCATTCTCAGGCGAATAGTTTGCAGGAAACTGTAAATCTCCTTGTGCTTCTAATGTCTTAACTCTAGATAGAACGTTGTCGCCCATTTTATTGTTTTTTAATAGTAATTCATTCGTCATTTTATATAGTCTCCATTCTTAATTTTTTATCTTGTTCATTTACTATCAATTGAATTTGTTGTGATTCTGTTTTGATAAGCTCTGTTACTGATTCAGCATTATCAATAAATATTGGCGCTGTAACTTTAAAATGTTTTGATAGTGTGTTGATGATATCTAAGCCAACATTAATTCTTGAGGCGTTATTTAAACCGCTGTCATACTCGACACCATTAACCGTTGTTGAACATGTTTCTTCTAATTCGCCGTTAACTAAGGTATTGAATAGCTTAAATTCAGCAATATCAAATTCGTTATTGATGTTTTCAGTAAGCATTTTGACTTTTGTTGTTGTAAATTCTTTTAAGATATAAAGGTCATGTGAATACTTTTCTTTTTCATCCAATAATCTGTCTTCTTCATTTCTTAATTCAGAAATAACATCATCTAGATGTTTATTTGATTTTTCGATTGATATTGACACTTCAATTTCTGATTTTTCTTGAGTAAGTTCGCTTATTTTGTCATCTATTCCTGAAACTTTATCTTGAATAGTTTTCCTGATGTTAGAGCGTTTTTGATTAATCTCATTTATCTCTAACATTACTGCTTTGTATTCGTCAGTTTGCGTAACGTCAACGTGAGTTATTTTCAACTTATTAATTTTGTTTTGTATTCTTGCTGAACGCTCTTCTGCTTCGTTGATTTTAATTTGTAAATTATTGTTGTCATCCTCTAATTTCTCGATAATTGGCTTTATTTTCTTGCCCTCTGAAATAATGTGATTGATAGATGTTTGTATTGTTTCTAATTCTTTCGATTTGTTTGCATTGAATTTCTGCAATGCTTTTTCTCTTACCTCACTCACTTGTTCAGCTGGTAACTGTTGACCACAACAACTACATACATTGTCATCAAGATATTCAAATTTTTGATTTTTAGCTTTTTCTAAATCACTTTTTAATCCTTTATGATTTTCTAATAATTGATTACGTCGATTTTCTTCATGTGTAATTTGTTGTTTGTTTTGCTTTAATCTTGTTTTAAGATTCGCAACCGTTCCATTTTCAACGTGTAGCTCATTTGTTAAAGCATGTATTTTGTTCTCATTACTGGCGCTATTATTAGCTTCTATGCGCTTCAATTCTGATTGTTTATCAGCTAATTGGTTACGCAAATTAATTTCTTCTGCACCGTTTTGAATATCTATACGCTCATTTTCAAGTTGCTCAATTTCTTGTTTTATGATTGTGTGTCTATCATTATCGAATTCCGGTACATCCTGCTTATTTTGTTGCGTTTGGTTAATACGTATCGGAATATCTTTGATATCTTTGTTAATCTGTTTTATCTTGTCTGTAAGAATCTTTTTCTTTGTTTCAATTTCGTGATCTCCAAGAATATTATTTAGTTCTTTAAAATCATCATTTGTTTTAATGACATCCTCATCATTGATTGGTTTAGCGATTTCAAACAACAAACTTCTTCGTTTCTTCCAATCTAGTAAGTTAAATGCTTGAGGGTTCGTAATTAACTTGAATACATCTTCATCAATCAGTTCATCAATACGAGCTTTATAATCCTTTACTTTTATTGATTCATCATTGATATATTGTTTCTTCGTTCGACTTCGTGAGTATTCCTTGCGATTCGTTTTTTGATTTATTGTGTACTTAGGATGTGACTCTTTTTTAAAAGTCGTAATTTTTCCGTCGATTTCAAATTCTGCGAAAACAGTCGGAATTAACTCATAATTTTCTTCGTTTTTTTCGTTTAAAGGTACAGGGTTAAATGATTTGGTTGAACCGTCTAAACCCTTATCGAAAAGCAGCCATTGTAATGCGGTTGCTGTTGTAGTCTTGCCAGTCGCATTATTGCCGTATATTTTTGCATCTTTACCGTCAAAGTTAAATTTTTCTTCTTTGATTCCAGCAAAGTTCGATATAGTTAACTTATTTATTTTCATATCTTTCCTCATGCTCCTTTTTTAATCTTCCGATGACCTCTTAGCACCTCGATAATTAAATTTTTTATTCGTTCATGGCTGTCTGGATTGATTTCATGTATCTGCACAAGCTTATTGTTTGTTTTGTAACTGTCGTGATAGTGCAAGAAATTAATCGATAAGTATCCGTGATGATTACGTTCAATTTCCAATAATGCTCGTTGGTTTGACAAAGTATATTCGTCGAATAACGTCTTAAAAATATTCAATATATTTCTTTCTGTATCTCTCATGCTTATACCTACCATTTCATGACTAAGTTAATTAGTCTGTCCTGTTCATCTGTGTTATTTTCAATCCATTCATAAATACTTTGTTTCAAAATATCTAAAGCTGTGTATAGATCGTTCTCGTCAGAAACTAGTAGCCCGTCAATTGAATTTCCTTCATGATCTAAAACGACTATTTCGACACTATATGCTCGCTTCTTAACTCTTAATTGAAAATCAAAGCCATCTACATTAAATATTTTTCGACATACGTCACCCGTTTTGTAATACATTGTTTTAGTCCTCCTTGTCGTCATCTATACCGAGAATTTTTTGTGATTTACACATTTGGAGAACATTGACAATATCTTTATAACTCTTAGTGCTATCCAATAAGTAAGCAAGATCAAAAGTATGACCAATCACAGAACTTGAACCTGCTAAATAATCTCCGTCGATAACTCCTATTGATGAGAAAAGCAAAATATCAAATTTACTTTCTCCCTTAATTTCTTTCGCTAATTCATACAATTCTGCCGTTTTTTCAGATAATAAGTCTTTTATTTCTTCCTGCGTCATGTCTTTATAATTTTTAGTCATGGTTGACTTCCTCCGTTTTTCGTTTTATATTTAACTTGAATTTTATTTCTTAAATGTTTGTTACTGTTACTTGTTGGCGCAAGTAGCAGTTTTTTTATTCTTCATAAAAGTATTCCTTATAGAATATGAATGTTGCGATACTTGCGAATCCTGCAATTGACCATGCTGTAGTGAAGTATAGAAACGGCATAAGTACAATCGCTAAGACTGTGAAGCATAGTACTGCTACTAGGTAGCTTTTATAAGTTTTACTCATTTGTTGTGCCCTCCTTTGTAAATCTCATTAAAATGTTCATCTACAAACTTATGCATCCTTCTTGCGTTAAACCTCCAACGATTAAAATTCTCATCAGGATAATGTACGATACCTTGTGCTCTTAACTCTTTTTCGAGTCTAGGGTGAAATAATAACCTGTCTTTGATTGTTTCATCAGATGCAATTTTTAATTTCTTCTTTAAGTCGCTCATGTTCCATACAGGGTCTAATGAGTAAGCTATTAACTCTTCATATTCATCTTTTGTGATAAGCACGTGTGTTTCAGGTATTGGAACTGTTACGTTTAAAATATGTGGCATTTCTATCTTTCCTTTCGTGTATAATGTTGTTATCAACCTAAGGTAGTGATAAGTATGAAATTAGATCATGATTGTGTTAGACATCTTTTGTTAGAAATTGAAACTAATAAAAAGATTGGTGAACCGCTCACCGAATACAATTTCAAAGATAATGTTGTATTTGGAAAATATGATTTTGAAACTGTAATGTATGCATTATTAAAACTGGAAGAAGCAAAGTATGTTAGTGTTAAATTCGGTTGGGAAGATGGACATATTTATGGTTATACAATTAACGATATAACTTGGTCAGGGCATGAATTTTTAGATAATATCCGAGACAATCACACTTGGAAAGAAGTTAAAAAAGTCGCAAACAAAACCACTAGTATGTCCGTAACATTGCTAAGCAAATTAGCTTTTAATTATCTAACACAAAAATTTAATCTAACTTAAATTCTTTTCCATCTATTAATCCATAAAAGTTATTTTTTAAATGCGGATGTCTTTCAAGCGTCATTTCAATAAAACGCTGGTCTATCATTAAGTCGTAGCCATCGTTGTATTGAATATTAACGGGTCGTCTATTACATTCTTCGTCATAGTAGTAATAGATGACTTTTTTGTTTTGAGCTTGCATTGTTCGTTCCTCCTATTAAGATGTTTGTTTTTCTCCTAAAAACTTATTAACAAAGTATTGTTGTCCTTTGCCTGTTACTTTTGGCGTCTTACTAATTGATGTGTGACCGTCCGAATGTGTGATTGATGTTTCTTTAATTTCGAATAACTCACGTTCCATTGAATACTGTGTAGGCATGTTATAATCCACACCCTTGCGTTTAATAAGGAATCCGTTTTGACGTAACCACTCAAACAATCTGCGTTGCCCGATGTTTATACCGTTTTGTTTAATGATCTTTGCTAACTCTCCAACTAAAATTGATGTCTTAGTAGTAGCTACTGCATCTGCAAATACAATTTTTGGTTTATCACGTTCAATCTTTGTTTCTAATTGATTGATTGTGTTGTTAGCAATTTTTAAAGCACGTTGCATAATCATTTCTGGGCTATTCCATGCTTTTTCAACTTGGATGAAGTATTGTCTTGCACGTTTGCCAGGTTCACTACGTTGAATCATTGCAATCTCTTTTGCAGTGTCTAGTGTGAGTGCGTGGTCAGTTTGATTCTGACGACCTCCTAGTGGGTTATGGACAAAAATGTCCGTGACTATATAATCGATATTTTCTTCAAATCCGTAATCACTCATTCTTTCAAACCATTTTTTGTATGGAGTCTTAACCTCTAATGCTTGATGAAGTTCTCGACCGCTGATTGCGATTTCTCCATTTTCTTTTTCTTGTATGTTGAACATTTCGCCTATGTTCGATTTTGTTTGTAATGCTTGCATATTGTTTGTGCTCCTTTCTGCTATACTCCTATTAAGGAGGTGAATGACTTATGACTGATGAAGCTAAATTTGTCCTTTTACAACTTTATTCAATTTACCTTGGTAGAATTGACGAAGGTATGTCTAAACATTCTGCATCTTATTTCGGTAGTGATGAATCCTCATTTAACGCTTTCTTTTTAGGTTTTAATTTTGAAGACTATATCGATGCAGTTCTTGAATTAAAGCATAGAGATTTTGTAATTGCTTCTGCTGAAGATGGCGGTTTTCTTGAGATGGCTCTTTCTCGAGAAGGTATCGCCTACTCAGAATCAGAATCCAAAAAAGATTACAAAACACTTATGGGTTTAATTAGAGATTTGAAAAAATTAATAATCTAAAATCCAATCATCTGCTATTAAATCGTCTGCGCTAGGCTGCCACCTTCCGGCGGCGGTTTGTCTTTTTTTCTTATAGTGTCTAGATACGACTAGGCATTGATAACGCTGCAAATTAGTTGGTAATATCCCATACACATCTTGATTCTCTCTCCTTATACTTATTCCTTTCTCCATCGCTAGCTTCGTTGCTTCTTGAATGTTCATTTGTTATTCCTCCTATTAAGATGTTTGTTTTTCTTTAAATGCTAAAATAATTGATTTCTTTTTATCGTTCGTAAATACGAAATTTTCGTATTCATTACCTAAAAAAATATCATCATATTTAACATTAAAAGCACTCATATACTTAGAAAGTAAACTATCTTTAATGTTTGTAGAGTCTTTTTCCATATTTTGAATTGTACGTGATGAGACCTTAAATAAATCTCCTAACTCTTTTTGAGTCAATCCGTAATCAGTCCTCAACTCTTTTAATGTTTTCATGTTGTCACCGCCTTTCGTAAACCTAATATAATACGAAATTTTCGTATTGTCAACATTAAATACGTTTTTTTCGTAAAAAACTTTACTATGATATGAAAATTTCGTATAATAAGAAAAAAAGGAGGTAAGTAATATGAACAAAGAAAGAAATATTATTATAGCCAAAAACATTAGAAAATTTCTCAACGATTCAAATATGTCTCAAAAGAAACTTGCTGAACTCATTAACATAAAACCATCTACTTTAAGCGATTATTTAAATTTACGTTCCAACCCCTCTCACGGCGTTATACAAAGGATAGCTGATGTTTTCGAGGTTGGTAAAAGCGACATAGATACTACATACAAAGACGATAACGACATCACTTCCATATACAACAAACTCACACCTCCCCGCCAAGAAAACGTACTTAACTATGCAAATGAACAATTGGAAGAACAGAATTCTAAAGGAGATAACGTTGTAGATATTAATTCATATAAACAGGAGAAAACTCCAGTTAACGTCAATGGTTGCGTCTCTGCTGGTGTAGGAGAACGTTTACACGATGAAACGCTATTTACTGAAATGGTTAAAGGACCTATCCCCACACACGATTTAGCGTTAAAAGTAAATGGTGATTCTATGGAACCTATGTTTAAAGATGGCGAAATCATATTTGTGGAGAAAACTCACAATATAAAGAATGGACAAATTGGTATATTCATCATTGAAGAAGAAGCGTATGTTAAGAAAGTCTTTGTTGAAGATGATAGATTGACTCTAGTTTCACTAAATAAAGATTACGACGATCTACACTTTTATAGAAATGAAAGTGTGAGGTTAATTGGAAAAGTTATTTTATAAAAGGAGCACTTGCAAATGAAAAAATATGATATTGCAGTCTTAGACTTTGAAACTATGAATGAACATATGAACAGCCCTTGCGAAGTTGCTGTATCTTTAATTAAGGATTTATCAATAGTAAAAGTTTATTCATCTTATATTAATCCTCCTAATAATAGATATAACTTGAAAAACGCTAAAATACATAAAATACCTGAAGATGTCATATTAAAAGCACCTAAATATCCAGATATTTACCAAGAAATTCTCTATCTTTTAAAAGAATCACATTTAATTATTGCTCATAATGCACTTTTTGATATTTCAGTATTAAAAAATACTAATAATTATTATGACTTACCTGTTCCAAACTTCATGTATGTCGATAGTATAAATATCTTTAGAAGCTTCCACGCAATCTCTAGTTTTAAATTAGAAAATTTGTGTAGCTTATATGATATCGATAAAGAAAAATTACATTCTGCTAAATTTGACGTGCTAGCTTTATCGAAGATGTTGATATCACTCGCTAAAAACAATCAGCATTATAGTGTATTAAAATTAATACATTATATGCCTAAGCAATACATTAGATTTAGCAAATATTCTAACTCTCCAACTAAACTTTTCGATTCAGGATTTCAAAAAATTCATATGAAAATATCTGAGATTAATAAAATAGAAGTGGAAAGTGTAATCCCTATTTTAAAAGATAAAAATGTTGTTTTTACAGGTAATTTTGACACTGAAAAACAAGATTTAATGATATTAACTAGAAAGAAAGGAGCTTATATCAGAAGTGACGTAACTGCAAAAACAGATATTTTAGTCGAAGGTGTTCAAGATGATAAATATAAAGATGTGAACGGACTAGTTTCAAAACAACGAAAAGCTCGAGAATATGTTGGAAATGGTGCAAAAATTCAATTTTTAAATGAAGAAGACTTAATAAATTTAATAAAGGAATAATAACGATGATCAAAAAAATTTTTACAAAAAAACATGTATTCTTAGTTATAGAAGATGAAAACCATAATCACAGCGATGCTGTTTTTGGAAAAAGTATATTACTTTCAATTTACGTCGGTGTGAATAAAAAGACTAATTCTAAATCAGGGAAATTTATATACCTTGACAGATCTAAAAGAATCGTTAGACAATCTGATATCACCAAAATAGAATCAGCTAACGAAAATGATGTAGATTTTTATAATTTACTGAAGAAAGAAAAGGAAATTGTTTATTCCAAAAATATAGTAGATAAATACAATTTAGCGAACTATATAATTTACTACGAAGTTAGTACTAAAGAATAAACCAATCCATTATTTCATAATACTAACCTTAAATTTACAGAGGTTTTAATTATGAAACATGAAAAAAGCAATCTTAACTTTAAGTCTTATATTTATTACCTACTACCTCACTTTTAAATATATGTGGATTAAAGAATTGAAGTATTAATCATGCTTATTTGAAAAAGACGTCTATTTCAGCAGTGTTTGAAAGGAAGTTTATAATGAAAATAAAAAATTGCAAAATAAAAAAAGAAACTATAGTATATGAAGTTTTAACTAGTGGTAATCAACCATTCACTTATGAGTTACCTAAAGATTTATCGTCACATAATGCGCGTAAATACTTGGAATTTATTTCACAAAAATTAGATGGCGATAAGTTAACCAAAGAAGATTCATTATGATTTTACTAAACAAAAAAACGCCTACTAGTGTGAAAACGTATTGATTAATAGCGCCTATGTGGCGCTTTAATATATAAAGTAAGCAAAGGAGAAATGAAAATGAAAAAAGTAAGTGTTATAATGCCAACATTCAATAACGGCGAAAAATTACATAGAACCATTAGTTCTGTATTAAATCAAACAATGAAGAGTACTGATTACGAATTAATTATTATTGATGATCATTCAAATGACAATGGTGAGACTTTGAATGTTATAAAAAAATATAAAGGATTAGTTCGTTTTAAACAATTAAAAAAGAATAGTGGAAATGCTAGCGTACCTAGAAATACAGGCTTAAAAATGAGCAAAGCTGAATATGTATTCTTTTTAGATTCTGATGATTTACTTCACGAAAGAGCACTAGAAGATTTATATAATTACGGCAAAGAAAATAATAGCGATTTAATAATTGGAAAATATGGAGTTGAAGGTAAAGGAAGAAGTGTTCCTAAAGCTATATTTGAGAAAGGAAATGTAGCGAAAGCTGATATTATTGATAATAGTATTTTTTATGCTTTATCAGTACTAAAAATGTTTAAAAAAAGTGTTATAGATAAAAACAAGATAAAATTCAAAACATTCTCTAAAACTGCTGAAGACCAATTATTTACTATAGAATTTTTGATGAATTCGAAAAATTACTCGATAAAAACCGACTATGAATACTATATTGTAGTCAACGATTTCGAGTCTAGCAATCATTTGTCAGTAAATAAAAGTACAGGAAATCAATATTTTGCTACTATAAACGAAATTTATAAAGCTATTTATAAAAGTCCAATTTATAAAAACCAAGAAAAAAGACACCAACTTGCCGGGAAGTATACAACTAGACTTTTAAGACACGGTCAGAAAAAGAATTTTGCAAATAGTAAAATGAAATATGAAGATAAAATCGAATGGTTAAACAACTTTTCTAAAACAATTAATAAAGTACCTAGAGACTCAGATAAATATGTCACACAAATATTCAACTTAAAATTAGAAGCAATAAGACAAAACGATTTATTAGCTGTGATGATTGCAGATAAGCTATTATAGGAGGAAAACAATGGAAAACTTTAATTATAATAACATAAAAAAACTTGTTCTTGAAAATGTTGATATAGATAAAGTAAAAGAAGTATACAAAGATTATGAATTACTTAATTATACAATAAAAAACCAAACACTTTACATGAACGATTATGAAGTTGCTAAAGTTTCTGAAAAACATCTAAACGAAAATATTAATAATCTAAGAGGCACGGTTAATCTAGACGAAAAATGTATTTTGTCACTAACCTATCTATAATGCGAAATTTCGGGTAGCTCGCCTACCCTTATTATTTTTTGCCAATTTTGAGGAGGGAACACATGAAAACACGTTGTTACGATGGTAAAAAATGGCAATATGAGTTTAAGCATGAAGGAAAAAGATACCGTAAGAAAGGTTTTAGAACAAAGCGTGAAGCTAATTCTGCTGGACTAGACAAGTTAAATGAGTTAAGAAGTGGTTTTAATATAGATAACTATATAACTCTTGAAGAATACTTCGAAAATTGGATTAAAACGTATAAACAACCTGTTGTTAAAGAAAATACCTACCGTCATTATAGAAATGCATTACAACATATACAAAAACATAAAATAGGTAAAATGGAGTTATCAAAGATAAATAGACAAGTTTATCAGAAATTCATAAACGACCATTCAAAAGAACACGCAAAAGAAACTATAAGAAAAACAAACGGTGCTATTCGGTCAGCTTTAGATGACGCATTATATGATGGACTTATTTTTAAAAACCCCGCTTATAAAGTTAATTATAAAGCCGGAAAACCTACGAAGTCAGAACAAGAAAAATTCATCTCGGTAACTGAATATGAAATACTAAAAGATCACGTCAGAAAGAAGAGAACTCGTTCATCATTAGCGCTATTCATAATGATTTGTACGGGTTGTCGTGTCAGTGGTGCAAGAAATATAAAGATTGAGCATATCAACCAAGTGAAAAACACTATATTTATTGACGAGCGAAAAACCGATACTTCCCCTAGATATATCAGTATCGCTAAATCTGATATGAAACACATTATGGACGTCATAAGTACATTTGCAATTAGCTATGATGGTTACATTTTCAAAGAAGCCGGATCTATAATTAACCTTCAGGCTATCAATAATGCTTTGAAATCAGCCTGTAGAGTCAATAATATACCAATTATTACATCGCACGCATTAAGACACACTCATTGTTCTTATTTACTAGCAAAAGGTGTATCTATACATTACATTTCTAAAAGATTAGGTCATAAAAATATAGCAATAACTACATCCGTGTATTCTCATTTGTTAGAAGAAAAATTTAATGAAGAGGACAAAAAAACAACTAAAATTTTAGAAAGTATGTAATTTAGGGACCCATTAGGGACTCCAAACCCAATAAATACTGTTGTTACAAGGTTTCTATGTATCCAAACTGGGGACAATATAAACGCGCTGATTTAATCGGACAATCTTCTTATATTAAAAATAATGATGTCGTAATATTCAATGAAGCATTTGATAATGGTGCATCAGACAAATTATTAAGTAATGTGAAAAAAGAATATCCTTACCAAACACCTGTACTCGGTCGTTCTCAATCAGGTTGGGACAAAACTGAAGGTAGCTACTCATCAACTGTTGCTGAAGATGGTGGCGTAGCGATTGTAAGTAAATATCCTATTAAAGAAAAAATCCAGCATGTTTTCAAAAGCGGTTGTGGATTCGATAATGATAGCAACAAAGGCTTTGTTTATACAAAAATAGAGAAAAATGGTAAGAACGTTCACGTTATCGGTACACATACACAATCTGAAGATTCACGTTGTGGTGCTGGACATGATCGAAAAATTAGAGCTGAACAAATGAAAGAAATCAGTGACTTTGTTAAAAAGAAAAATATCCCTAAAGATGAAACGGTATATATAGGTGGCGACCTTAATGTTAATAAAGGCACTCCAGAGTTCAAAGATATGCTTAAAAACTTGAATGTAAATGATGTTCTATATGCAGGTCATAATAGCACATGGGACCCTCAATCAAATTCAATTGCGAAATATAATTACCCTAATGGTAAACCAGAACATTTAGACTATATATTTACAGATAAAGATCATAAACAACCAAAACAATTAGTCAATGAAGTTGTGACTGAAAAACCTAAGCCATGGGATGTATATGCGTTCCCATATTACTACGTTTACAATGATTTTTCAGATCATTACCCAATCAAAGCCTATAGTAAATAGTGCTCAACTAACTAATAACTCGCTTCGTTCTAAAAGGACGAAGCGAGTTATATTGTTAAAATTTGAATTGACTTACATTTTAATAAAATCATCTTAACAACTTTAATTTTTCATTAATACAAGTCTTTACTCTACACTCAAACAAGATTCATACACTGCACATCATAATAAATCTATCTACTCAAATATAAATAAAAGTTACCTACTACATTCTATGTAGCAGGCAACTTTTATTACTTATTTCTTTTCATTATCATTAAGTACTTTTACAAACTTCACATCATGTGTCTTCCAATCAACTTCATATAATGCTGATAATTTTTCTTCTTTTTTATCTACATGGTTTTCACCAGACCAATAGCCCCAGAAACCATGGCGATTCCAATCTATTTTAAACTCATCCATTGATCTTTTATAATGAACAACAAATTGTGATTTACCTTTGTCTTTTTTATCATGTGACATAACAGCTAAAAATTCTGGATTAAACCCTTCAGACACAGTTACAGGCATTTTGTCTTTAGGTGTGAAATTATCTTTCGCCCATAAATTTCCATTTCGTGTTAAAGAAAAGATTTCACTTTTAGTTCTATTATCACTATCATTAGTTAATTGTCTCGTATGGTCATGTCCCATATTATTTATCAAATGTGCTTCTACTTTCCAACCTACACCTTTATGTGACGTAGATTGATCAAGTAATGTACGATATGATGGTTGTTGATAACTAATCGTCTCTGAATAATTACTCTCTTTTGTAATATTTCCAGTTAAGCCTCCACGATTAATCGAAAAATCTCCACCTGTTTTATAACCATACGTATATTTAACTTCTCTTGATTCATCCTGATTTTTTGGTGCAAAGTCAGTCACATTTGTATTGTTGTTGTCATCAACATTTTGAATTGAAACTGAATAAGATCCAGGCCATCTTAATGTACTATTCCAATAACCATTTGGGTCTAAAATTCTCAAACCACTACCAATTGTACCTTTTGCTTTAATAAATACTGTTTCTTTATCATAATTAGGTTCAGTTAAGAAATTAAATTGTAAGCTTTGAGTAATATTTTTTTGACTATCACTTGTTGTAGCTGTACGTGTATACATTTTAGTATCACCATCAAGATTCTTCTCAGAAACAGCTTTAATTTCAGAATTAATTTTTGCATAAGAAGTTGCCGGAAATACAGTTAATGCAGTAGATATTGCTAAACTACAAATTGTGATGTTTTTGTATAATTGTTTAATCATTAGTAATCCGCCCTTTCAATATTATCCTTCTTTATAAGGTTTATTGTCATCAGAATATTTATCAACGACTTTAACTGTTTTATTTTTCCAATCAACTTCATAAGTGACAATTAACCTTTGACCATCTTTATTTTTTTCTAAAATTGGAGGTGCATAATGTATTCCAGGTCTGTTTTTCAAAATATCTTGATTTCGTGTGTATGTTACTTCAAATTGCGTTTTCTCATTTGACTTTTCATTAGATAAATAAGTTAAAAATTCTGGATTAAAGCCACTTCTTACTAATGCTGGGTATCTATATTTTGAAGCAAAGCTTAGTTCAGGGTTTTCTACAGTAGCAATTCTCGTATTTCTATAGAATAATAATTCATCATTTCTATTTTTCACTTCTCCACCATACTTCAAGTCATTCGCAATAACTGACCAGTGTACATGCCAGTTATTATTTTTACCGCTGGCAATTGTGTCATAATTTTGCTGATTATAACTAATCGTTTTGGAGTAGCTATTTGATGAAGTTCGTCCAATACCTTTCGTTGAATCGAATTTACCACCTGAGCTATATGAAAATGTACTGTCTACTTTCGCAGTTGAAATTTTATTTTTCGGCAATTGGTCTAATATTTCAGTTTTACGATTTCTTTTTACTTGAAAATCTACATGGTACTCACTTGGATACTTTAACCAATTTGAATTTTTTTCTTCTTTATGAGATTCAAACTTTAAATTTGAATGAATTGAGCCTTGTTTTTTAACAAGTAATACATTCTTGTCATAAGTTGGATCATCGATAAAGTCGAATTGTAAATTTTGGAGTATATTTGTTTTCTCATCATATACTGTTTCAGTTCGTTTTGTGATTTTACCGTTTTTCCCAATATCATCAGGTACTGTTGAATTTTTATCTTTATTAGTAACATTACGTTTGTCTTTTTGTTGAGACTTATCAACATGTTCTTTCTTATTTTGATCTTGCGAGTCTTTATGAGCTGAATTTGCTTGAGTCGTTGCTGCTGATAACAATAAAATTGCACATGATAATGATGACGCTATTAAAACACGTTTTTTATTTTTCATTGTTATAACCTTCTTTCGTATGATTGATATTTGTTGATATGTATCGACATGTGAATAATATCACAAAAATAGAGAATATATATTTAACTATTTATTAAATGATTTTGTTAATATTATTAAATACTTTATCCTCTTTAAAAATAATGTGTGTACAAAGTCATTAATTTAGCAAATATTTTTATTTAGTAGTTAATAACCATCGATTTGAAATTTATATATAATTATTAGCTAAATAATATCCTGCATCTTTCTCATACAATTTACTATAAAATTAAGCATACCCGATATCAGTGTTAATAAGATCGTTGATACTAGACAGTTAATTTCATAGAACGAAATCAAATAACACGCTACTTTCTGCATTTTAAATTATGTTTAAGAATAAAAATTATGTTTATATAAATATATATACTACTTTGAAAAGGTGTGAGCTTAATGACAACTTTTAGTGAAAAAGAAAAAATTCAATTACTAGCAGATATTGTTGAACTACAAACTGAAAATAATAATGAAATAGACGTTTGTAATTATTTAAAAGATTTATTCGACAAGTACGATATTAAATCTGAAATTTTGAAAGTTAATGAACACCGCGCCAATATCGTTGCAGAAATCGGTAACGGCTCACCTATACTCGCATTGAGTGGTCATATGGATGTTGTTGATGCAGGAAATCAAGATAATTGGACTTATCCCCCTTTTCAACTCACAGAAAAAGCTGGCAAATTATACGGTCGAGGCACAACGGATATGAAAGGCGGTCTGATGGCTTTGGTCATCACACTCATTGAATTAAAAGAACAAAATCAATTGCCTCAAGGAACGATAAGATTACTAGCTACTGCTGGCGAAGAGAAAGAACAAGAAGGTGCCAAATTATTGGCTGATAAAGGCTATTTAGACGATGTAGATGGCTTAATTATTGCTGAACCAACTGGATCTGGAATTTATTATGCACATAAAGGGTCTATGTCATGTAAAGTAACTGCAACTGGCAAAGCTGTCCATAGCTCAGTTCCATTTATTGGTGACAATGCAATTGATACACTGCTTGAATTTTATAATCAATTTAAAGAAAAATATTCAGAGCTTAAAAAACATGATACTAAACATGAATTAGATGTTGCACCCATGTTCAAATCATTGATAGGAAAAGAAATTTCTGAAGAGGATGCAAATTATGCATCTGGTCTTACAGCTGTATGTTCGATTATAAATGGCGGCAAACAATTTAACTCTGTACCAGATGAAGCTTCACTTGAATTTAACGTAAGACCAGTTCCTGAGTATGATAACGACTTTATAGAATCGTTTTTCCAAAATATCATTAATGATGTGGATAGCAATAAGCTTTCACTCGATATTCCAAGCAATCACCGACCTGTAACAAGCGATAAAAATAGCAAATTAATTACTACGATTAAAGATGTAGCTTCTAGTTATGTAGAACAAGACGAAATATTTGTTTCAGCGCTTGTAGGTGCAACAGATGCCTCTAGTTTCTTAGGAGATAATAAGGACAATGTTGATTTAGCCATTTTTGGACCAGGTAATCCATTAATGGCACATCAAATCGATGAATATATTGAAAAAGATATGTACCTGAAATATATTGATATTTTTAAAGAGGCTTCCATTCAATATTTAAAAGAGAAATAAGAACGATGCTGTCAGCTGCCCTATTCGCGTGCTGGCAGTTTTTTATTGCGAATTTTAAGTTGATAGAAATAGCGATGAATATTGTTTGACTGTAAATATTCAAATATCAACAAGCACATTTTCATTGATTAAGTGATGTAAAACTGAAATTATGGTGGTGATTTGTCATACATATATTGCATTGTCTATTGAAATTGGGAATCCAATTTCTCTTTGTTGAGGCCCCCACCCCAACTTACATTGTTTGTAGAATTTCTTTTCGAAATTCTCTGTGTTGGGGCCCCCACCCCAACTTGCATTGTCTGTTGAAATTGGGAATCCAATTTCTCTGTGTTGGGGCCCCTGACTAGAATTGAAAAGTAATACACATCAGTAACATTTCTATTTTCATTTATGATATTATCTAATTATTAATTTATAATATAAAGGAGTATGCAATTAAAATGAACAAAGTCCACAAACCTTTATATTTTTATTTAATGCTTTTCTTCTCTACAACTATCATAGGTGCTCTTTTATTATATTTACCTTTCACTGGTAAAAAGCCAATATCTTTTTTAGATGCCCTATTTATAGCTTCAAGTGCATTTACAGTTACTGGCCTATCCCCAGTTGATATAGGATCACAGTTTAATATACTTGGTGAAATAGTAATACTATTATTAATTCAAATAGGTGGTCTGGGTATCGTGACCGTAACCCTATTGACACTAGTATTTTTAAATAGAAAGATATCAATGAAAAATAGATTCTTGATTATGGTTACATGGAATATTGACGAACCTGGTGGTGTTATTAAGCTAATTAAACACTTGGCTATTTATAGTTTAGTCACTGAATTAATTGGTATGATTTGTTTGTGTTTATCTTTTATACCAAAATTTGGTATAGGCAAAGGTTTATTTTTAAGCTTATTCACATCAGTATCAGCTTTTAATAATGCTGGATTTGCCCTTTTTAAGAATAACTTAATAGATTATTCTAGTGATCCAATTGTCATTATTACAATCTCAATACTCATAATATTTGGAGGTATTGGACATTTTGTCGTAATAGACTTTATTAATTGTAAAAAATTGAGTAAATTATCTTTACATTCTAAATTAGTCTTAACTACAACTAGTATCCTAATAATTATAGGAGCTATTACATTCTTTTTATTAGAACAGTTTAATACTATGCAACATATGGGACTAGTTGAAAAAATCGGAAATTCTTTTTTCCAATCAGTAACAACACGAACAGCGGGTTTTAACAGTATTGATATAGCAAGCATTAACAAATCTACCGCCTTAATGTTAATGTTACTTATGTTTATTGGTGGTGCCCCTCTCAGTGCAGCTGGAGGAATTAAAATAACTACTTTTGCAGTGGCGTTTATATTTGTTTTAAATTATATACGTAAAGAAAATAATGTTTCAGTATTCAATAAAGAAATATCTGACAAACATATAAAACTATCTATTGTTACCATTAATATCTCATTTCTATTTATCAGTATCATTACTTTTATATTATCGATAATTAATCCGAACATATCATTAATCAAGTTATTATTCGAAGTGGTTTCTGCATTCGGAACAGTCGGGTTAAGTATGAACCTTACCACAGAATATCATGGTATTACTAAAATAATTATTATATTCGTTATGCTTTGCGGTAAAGTAGGACTATTAACTTTATTAAGAACATTTATACCACCAAAAAGTCCTAAAAATTACCGCTACACTAAAGGACAAATTTATCTATAAAATAACTATCCATCTTTAACAAGAAATGAACTAGTGTTTTAATCTATTACATTTAAAAAACTACCTAAACAGGTAGTTTTTTGTTTTTTATTTATTTTAGGCCCATTAAATGTCTTATCTCTTTAATTAAGTAAAATGCACAAGTACACCTTTAAAAAGATTTACTCAAAACTAAACTATACCTAGTTAACCGCTTGTGATTAAGAAATTTTAAATGTGGTTTCTTTTAATTATGTCAACCACCCATAAGGATTTTAATCAAGCACTCATTCATTCCTGCACTCGCAATATGCATTACTTATAGAAGTGGATGCACTCTCATATTATGGCAATACCATAACTCCCGCACCATAATGATTTAAATACCATTATGAATCTCAATTACAAATTAGCACATAAAAAAGACGCCTCTCATAAGTTTAGTCAACTAATGGAAGGTGTCTTAAATTAAAATATTTTCATACGCTCTAATATTTATTTGGAACGAATCATACTCGTCTATCATGGAATGTTCTAGTTAGTCAAAACTAGAAACTGTTTTACATCATTCCCGGCATTAAGGGCGGTATGAAATAGATATAAATCACATACAAAAATACTATTAAATCAGTATCGTGTATTCTTTATACATTCAATTTTTTTAGTTTTTTTATTTCATTATGACCAATTTATGACCACCAATTATTACACACATAAATCTCTATAAGTATATTTGCAATGATCGATATGATGATTTTTCATTGCAATATAATGATTCTCTCAGCATCTTATATCACCTAATAAAGTTAATGTAAAATGTTAAAATTGATAAAACTATATAAATTTGTGCACCCAACATCACCTCATAATTAACGTATTCAAATACGTATTCACTGCCTGCAACGTGTGGAATGATACATATTTTTCTATAACTCTTCCTTTATAACCTTTTGTATTTTTTATGAATTTTCTAAAATTTATTATTCAACTTATATTTATAATGTTATTATAAATATAATGAAAAGGAAGTGCCTAATATGAAAAAAAGATTATTATTTGTAATTGTTATTACTTTATTTATTTTTTCTTCTAATCATACAGTCTTATCTAACGGCGATGTAGGTCCAGGAAATCTAAGAAATTTTTATACTAAATATGAATATGTGAATTTAAAGAATGTTAAAGACAAAAATTCACCAGAATCACACCGCTTAGAATACTCGTATAAAAATGATACATTGTATGCTGAATTTGACAATGAATATATAACTAGTGATCTAAAGGGAAAAAATGTCGATGTTTTTGGTATAAGCTATAAATATGGTTCTAACTCTCGTACTATATATGGTGGTGTTACTAAAGCAGAAAACAATAAATTAGATTCGCCAAGAATAATACCTATAAATTTAATTATCAATGGCAAGCATCAAACAGTTACAACTAAAAGTGTTTCTACAGATAAAAAAATGGTTACCGCACAAGAAATAGATGTCAAACTAAGAAAATACTTGCAAGATGAATTTAATATTTATGGACACAATGATACTGGTAAAGGTAAAGAATACGGCACTTCTTCAAAATTTTATAGCGGTTTTGATAAGGGGAGTGTAGTATTCCATATGAATGATGGTTCTAATTTCTCGTATGATTTATTTTACACAGGATACGGTCTTCCAGAAAGCTTCTTAAAAATTTACAAAGATAATAAAACTGTTGATTCAACACAATTTCATCTAGATGTCGAAATTTCAAAAAGATGATTCCAATTATTATAGTTTAGATTCACTGTATAAATAACCGCACTTTCTATTAATATAGAAGTGCGGTTTAATCTATATATATATGCATCCTAAAAAGGCAAGCACCGAAGTACTTACCTTTCAAATATATCTAATACTTTCACTTTTTATATCAAAATCGGATTAACATTATCCATTCTTTGTTGTAAGGTGGACTTCTATCTTCACACTTTTAGAATCAACCGTTTTATTGTCGTTGTACATCATTAAATATTTAGATTGGTCAAACTTATCGCCTGGTGCAGGCATCATATCATACCAAAAAGTATTGCCGTTATTTTCAATAAATTTTATATATCCTGTTTCATATGGTGAACTGTTAAACTCATACAAATTTTTTTTATTAATTAAAAAATTCCTAGCTTTTATGTCTAGTTCTTGAGCTGTTACACTTTTCTTATCAGTTTGCACTTCAAAAGAAATTGTGTTTCTTTTATTTTCATAAACTCTTACAAGTACATTTTGTAAGTTCCCATTATCAAAGTGGTTTCCTTCATGTTTTGTTATTCCTCCATACATACAAGTTTTACCACCTGTAACTTTACCTACATTATCTTTGGATGAAAAATAGCAGTTTACATAGTAATTTGATCCATACACATCAACTACTTCATCTTTGTACTTCTTTGCTAAATCTTCATTTAATAACTCTGTTTTCACTTTGTCATAATTTTTCAGTTTTTTATCACTAATGTTATAAATTAAATCATGTGCCAAAAATTTATCTACAGACTTAACTTTAGTTGCTGATACATAATGATCATCATATAAATATTTCATATTACCCATCGTACCAGTAAACTCACTTGATTTGTGCAAATCATCTGGCATAGGGTCTGGTTGACTCTCTGCTAAAACGTTGGGTGTAGAAATAACTAGTATCAGTGCGAATATCAAAATTACACGTGAAATAAATAATCTCTTATACATTTTTTATCTCCTTTATCCAACATTCCCAAAAAGTATCTAGATACACTTTAAATATATGTTATATTCTTAAATATTCAATTAAAAAATATTAAAAGAAAATTAATTATATTTAATGATTTATCTTTATTTATAGGAATTAAGTTATGCTTTGAAAATTAATTAACTATATTTCATTTGAACTTATATACAAAACTCTTTCTCTAAGAAAAACAGAGGATTTCTAAGCATCTTGAATTAATAACATTGTTTATATATTCACACTTTTATAATTAATGCATTCATTTTTGCAAATTCTAAAATTGGTTTCTACTGTTAATTTTATATTCATATATTTAATCTTATAGTCAAAATTATTTTTTTGCTGTTATAAGGAACTAGCTATATATTATATAACTACTATAACAACTCAATGTTAAATGCCATATGCGTTAATTGCCTATTTTGCTATAAAACTTAGTAAGTCATATAGTCGATTCCTATCGTATAGAGATATAATAATAGGCAAGTACCGAAGTACTTGCCTAAATATCAACAAGATTAACATGTGAATAATAATGGAAATAAAAAGTCAGCCCGAAGGCTAACTTACGAATAGATGAAAATTTGAACACATTGCTGTGTCTAAAATGATTATAGCATAAATGACGAATACTTCTAGCTCAAAATTATTATATTTTAATGATAAAATTTTATGTATTTGTTAATAATTATTTAATTGATTTACATAAATAATAATTGTAAAATTACTTTGTAATTGATTGCAAATAAGTTATAGGAGAAAATAAAATGAATAAAAAACTATTAACAAAAACATTGATAGCAAGTGCTTTAGTTTTAACAACAGTAGGTTCAGGTTTTCATTCTTCTTCAAATTATAATGGTATTAATAACGTTGCAAAAGCTGAGCAAACGACAGATAACGCATTGTGGAAAAATGTAAGAGACGCTTTAAAAGACGCGAATATTATCGATAAAACAGATAATGAAAATGTCAAGGTTACGTATAAAATAGAAAATGGTGGAGAAAATACCATAGAAGGAACAGCTAATTTAGAAAATATTAGTACTTCAAACAATCCTAAAATAAACCCTCAAAATGTTACAAAAATTAATATAACTAGAAAAAATTCGAACTACCCTAATATTGATGCTAATAATACATGGAAAAAATTAACAGAAAAATTGAAAGAAAAAAATATAGTGAACAACGGCGACAATGTTTCAATCTTAAGTACAGACCCTAAAGATGAGACTGTATTCGGTAAAGTAGGAGAAGATAAATCAAACGTAAGCAATAGATACATCAATCCTAAAGATATAAATGAAATTCAAATCACTAAAAAATAACTTTTTTCGAGAGGCAGATTACTCCTGCCTCTTTTCTTTTGAACAGTGATAATCTTCTGGATCTATGTAACACTCAATTACTTCAGATTCTTTACCTTTAACTTCCTTTAATTACTTTCTCTCTATCTCCTCAAAAAGTTGTGCTTTTTCATTTGTGATTGGAGTTGGGCGTTTTTTCATCGCGTTGTTTCAATTCCTTTTTAAGGTATTCTAATTCTCTCCTAGTCATATCAATTGTTTTTTTACTTCTCACCTTTAGTGAAATACTCTTATCCTTTCTCTTCTTGCGTTAATGTTGCTAATTAGTATAAAATACATGCGCCCATATATTCCAATGGTAGGACATTTAATTCTGGATTTTCAGCTATTTTCATAAATCTTTTATCTGATAATTTGCTTAATCCAATTTTCAAGCCATAGCCTAAATTCCCCATCCACTAAGTTATTTTGTTTCATATGGTTTTAATCTACGGCCAATCTCAAAGATAGATTGACCAGCGATGTTTAAAGTCATATTTCACGGATCCACATTTACGATAAACATATCTAGTTACACAATATTATCCCTTACTGCAACACAGGACGTTTCTCAGCGTAAAAAACACCACTAGAAAGTGACTTTAAAGAATATAACTAATTCAAACTTATATTAATTAATATTCTTTAAATGACCACTCACACTTTGTTTTTTGCTATTTGTAACTTTAAAATGTTGTTTAAATCTATATTTTTTTTTGATATAGCTCCCTATGTAACAAACACTTTTTAATTAATATATATTTAAACAATAATTTAGAGATGGTTAATTGATTCATTTAAATAATATTTATACATTCTATATGTAAACGTTTACACATTTGAATGAAGGAGAATTAAAAATGAATAAAAAATTACTAATGAATTTTTTTATCGTAAGCCCTTTGTTGCTTGCGACAATCGCTACAGATTTTACCCCTGTTCCCTTATCATCTAATCAAATAATCAAAACTGCAAAAGCATCTACAAACGATAATATAAAGGATTTGCTAGACTGGTATAGTAGTGGGTCTGACACTTTTACAAATAGTGAAGTTTTAGATAATTCCTTAGGATCTATGCGTATAAAAAACACAGATGGCAGCATCAGCCTTATAATTTTTCCGAGTCCTTATTATAGCCCTGCTTTTACAAAAGGGGAAAAAGTTGACTTAAACACAAAAAGAACTAAAAAAAGCCAACATACTAGCGAAGGAACTTATATCCATTTCCAAATAAGTGGCGTTACAAATACTGAAAAATTACCTACTCCAATAGAACTACCTTTAAAAGTTAAGGTTCATGGTAAAGATAGCCCCTTAAAGTATTGGCCAAAGTTCGATAAAAAACAATTAGCTATATCAACTTTAGACTTTGAAATTCGTCATCAGCTAACTCAAATACATGGATTATATCGTTCAAGCGATAAAACGGGTGGTTATTGGAAAATAACAATGAATGACGGATCCACATATCAAAGTGATTTATCTAAAAAGTTTGAATACAATACTGAAAAACCACCTATAAATATTGATGAAATAAAAACTATAGAAGCAGAAATTAATTAATTTACCACTTTTTCTGTAATAATTATTAATAAAGGGAGTCCGTTAATTATAATAAGCGTTCTCCCTTTTATCTTTATAACGCTTTAATATAAAGCTAGGGTGAATTAGTAAACTAATCCTCACTAACTCAATATGATAATCGTTTTTACTGTAATCAATCCTCTAACGGTATATCATCCACAATCACAGTATGATTAGGATTAGCGTTAGATACCTCTTGTACCGTCTTATCTAAATCTTCATCATCGCCATCCCATTCACCAATATTAATGAATATAGGCACATTCCCGTTAATATCATGCTTATCTGTAAATAACTTATGGTATTTACCCAACATATCACGAGCTTTTAAACGATCACTTGGCTTAATTGGCACCTCTACCAGTTCAACATGTTCGTTATAGACTAACTGTACTTTGCCACTTTGTGGATTCTCTTTATATTCTCCACGTTTGACCACAACTTCTTTCGTTTCTGTTTCATCACCGACTGCCGCATTCGTAAGCACATGTAGTAACTCTTTTGCGGTTAATACATTCTCATCTATAACCTTATCTTTTTGTTCTTGTATATATTGCTTGATGTGTGGCTTCTTTAATAACCTACATCCTGTCACATGTGCACTATTTGCGCTATAGCCTGCTTTTATGGCACTTTGTGTTACATTAAGTGTTCTTATATACTCATTCACAAAACGCGCTTGTTTTGCCGTTAACTCACTCATTCTATCACCTCCACAATTTTATCTAATAAGGTTTCATACCATAATCTTACAGATTGTTCTGAACACTCTAAGACATTGCTAATATCTTTAAAACTACGTCCTTGTATTAAAGAATCGAAAATATAAAACTCTTTATCATTAGCTACTTGGTCAACAATCATTTCTAAGTGATTCTTTACAATATGATCATCAATGTTATCGTCTGCCATCCATTCATTAGAATTTTCATCACCTATTGAAAAGAATTCATCGGTATTTATTTCATCATCTATCAACACATCACTTATAGTTCGCTTATGATAATCACAAACGAAGTCTTTTATTTGCTTTTTATCCATTGTTACACCACTTTTACATATGAAGATTGGTGATATGCATTTACTCGTGCAATCTTACTGTTTTCAATTGCTGTATTTCTTTGTTTTTGACGTTCTGAACGTTGTTTAATACTTGCTTGATACAAATCAACTTGTAAGCGTTCAATGACGTTGTAGGGCTTATATCGTCCATTTGAACGCATATATTTTACAACTTGCTTCTGCTCTTTTTCTGTATAATGATTTAGTACCTTTTTCAACAACGCCATATTATTTATAGATCTATTTTTATAGTTTTGTAACCCTGCTTTTGTTTCAATAATTTTGATAACTAATTTTTCAATCGGATATGAGACAGACACGACCCCCATTATTTCATCACATGTTGTGGTCGACGCACTCATATGGTACATACTTTCAATTTGGAATTCACACATCTTAATTTTTTTATTAATAAATGCTGGGTTAAATTGCGTTAATAGTTGATACTCAGATAGTTTATTGTCGCCATTACGATAATATAAACAATTCTTCGTTTTAAGCAGTTTCATTTATTCACCCCTATAAACAGAGCCTACCCGAATTGGATAGGCAATCATTGCTATTTAATAATCCTGTTTTGCTTAGCTAAATTTTGTAGCGTTGTACCATATTGCTTTTGCTTAGACTGTTCTGATTGTTGTAACTCACTTGAAATCTCCTGCATATTGTTTTTAATATCCAAATCAACTGCATTTATTAATAGATTTGTATCTGCTTCATTTAAACCAAATGCATTTGCGACCTTTTTAGTATTATTTAACTCGTATTTTGTTTCCATTTAATTACCCTTTCTTTTTAACGTTTTAAAAACAACTTGTTATTGTGTTCGTATGGCAAATCATTACCATTAATATATGATGTAAATATATTTTCTCTAAAGTAGCCATTCAATGCTTCCCTAGCCTCTTTATCATCATATAATTGTTCTTGACTATAAATACTCGCATATTGCTGATGCTCATCTTCATATCTATCATTAATATCTTCTATTTCATCAATGATCTCATTATATGCATCGACTACTTTTTTTAATTTACCTAAAGCTGATTGCTTTTCTGATTCGTATAATGATGACAACTCGCTTTGATGTTTTAATAATTCAATTGTCTTTTGATATTTAACTTCTTTCGACACACTTTTCTTTGTCTCTAAGCGTTTATTAAGTGCTTTTAGTTTCTTTTCATCAGCATCTGTTGCTTGATATAGGTTATCTGCTTTATCATCTTGTCCATCCATGATTAACTGTTTATATGTGGACTTATCTATCTTTATTTTACTCTCCAATGCATTACGCTCTTGTTCCAATTCTTGTATAGCCTTTTGTTGATCTATTACAAATTGGTTGTATTCTTTAAAGTACGATTCAGTTTTCATTTTTATCCCCTTTACACTTTAATTCGTTTCAAAGCTTCATAGCGTTTCATACTGCCATCAGCTAATTTCTTAATACTTCTCATCGCTTGTTGCTTTTCTTGTTCTGTCGTAATGATGTAATAACCACGTTCACTAGGTTTATAACTGCATCCGATAGGATAGCCATAATCATATACTAATGAATTGATTACTCTTCGTAACCATCGTTCATTGCTTGAATTATATTCATATCCCAATTGATTTAAGATTTTAGTTTTAGTAATATACTTATTGGACGTATTTTTTATCACATTGAAAACTTGCAGGTGTTCGGTGGGTAAATGATACGTCTCTTTTTCTGCGATACTTTGCATTTCTACACCTCTTTCTTTTAATTATTTCATACCTAAATTATACCATTTTTACAGGTCTAAAACAAACTTACGTTCGCTTTATAGCGCGTTTTATCAATTGTTTAGCTTATCATATATAACACTTATAAAATCATGTTATAAACTTAACGTTAGGCTTTTCACATTAACCTAATATAGAACTTAAGTTCGGTAAAATAACACGAACAAACAGCGAACAAACTTAACTTTTAGGCCTATGCCAAAAACACAAACTTTAGCTTGTATTAGCGTTAACAAAGTTCGCACACCTTGCACAAATCTTGCCATTTTTTCAATTCTCAAAGACTGTATACCTTCCGATTTTAAAAGCCAACACCTTCCGAAAACCTTACCATTTTAAACTGCTATACCTCGTATAAAATCATAGTATTTTATTAGGAGCCACACACTACATGTGACCCCTCATAACATTATTTACTCAAGCTATAGTAAGACGCTTTTAGATCATTCAATTTACGTTCTAAAGCCTTGTAATCCTCTTGTGTCGCATTCTCATCTTGTACAAACTCAGTTACTAATTTTAATCCCTCAACTAACTCTGGTGCTGGTTCATTGATTCCCGTAGCTAACTGATACAACATTTCAATATTCGCTATCACATCAGTATTACTTGATTGAATGCCCTCAAGTGTATCTGTATCAAATCCATTTTCTAGGTACTCAAACACATCACTATTATTTGATTCTGCATATGTTTGTAATCCATACATAAAATACTCATCTTCAAACAAATGACTAGCCATCATATCACTAATAGAAAGATGTTTACCGTCATGTAATTCATAACCTACATAATGCCCCTCTATGCTTCTTATAAGCCCCTCAGTGTGCTTAGGTGACGCTAATTCAAATGATTGCCTTACTTTACAATCTTTAATATATACATGACCGAATAGCTTGCTGTTCATCATCACGTATACCATATCAAATGGATCATTGTATAACTTAAAGCAACACGGTTGCACTTTACTATGTTCTAATAATCCTGTGTAGTACCTTAGTAACGTGCCTGCTCGTGTTTCAAATTGGTTTACGATAGTTTCTAAGTTCATTTGATTTTCTCCTCTTTATTTATTCTTAATACCATAGGCACCCATGAGGGCACGTCAGTTTGTTGTCCATCTTCTGGATAACAAATAGCTAATGGTAAATTAGGAACTCTACCATCCAACAAATAACGCATTATAAAACTACCTCTATACACTAAATCAAGTTGTTCACTTTTAACTAATTCAATCAACGCAAACATTGTAATTTTGTTCCATCCACTCCAAAACACAATATTCTCATCCTTATCGTGTGTGATACTAGTTCTCCCTATATAGTCGTGATTTATTTCTTTAAACAAATCTTCTAACTGATATATCGGTATCTCCTTATATTCTTTCACATATTCGTATATATACTTTTTAAGTTGTTCTTTATCCATGTGTAACCTCCATATTTATATTGATTGTGTACCATACACAGTTAAATACACACCTTTTTTTACTTTCGTGTACTGGTTAAAACATTGATATATATAGCCTCGTGATAATTAGTACACAAAGTACACAGAAATTTTAGTGATAGTTGTATATTATTTAGAAATCTACGATAATTAATTTATTAATTTTAACTATGACTATATATTTATATGTGTACATTGTGTACTTCGTGTACTATCTGCATGTAACTGTTGATATTATTGAATTTATCGAGTACACATATTTTAAAATTGAGTGTGTACTTGTGTGTACTAATAACTTTCTGTATATGGATTATGTGAAATCGAGAAATCAAATCCTAGTTCTTCAATTATTTCTTTTTTAATCGCATAACCCAGATGCCTTTGAGATTTATGTTTTACTTGTTTTTGAATTCTTTTTTTATCTTTTATTAAATAACCTTTTTTGTCCCATTGCCCTGTAATCGTCTGCATTTCGTGTCCTAATTTATTTTTAACAGTTTCGTTTTTAATACAAAGAAAATCATGTTTATATACCGCTTTAACATCTCCGTAATTTACTGAATCATAACCGTCACCTACAATATTATTTCTATTCGCATCTAAATATTGTAATAGTTCCTCTAACAGTTGCTTAGGTTTATCAATCGTCTTATTGTTTTTAACCATGCTGTCATAGGCTTGTTCGATAATTTTAAAATGGTCATGTTCAAACCCATCAATATCATTCAAAACCTCACCGGTAACTTGTAGTAACGCAAAGGCACGTCCTAAACGTTGCATGATTTCATTACTACCTTTTTGATTAAAATACCGTTGATAGCTCTCAAAAGCGTTCTTATACACGTCTTTTTTAGACTCATATTGTTTAATAAATGCCAACCCTAACGTTCCATAGTTCTCCCTAAACGATTTGTCTAATGTGGTAAAATCAAAATTATCTGGATATGGTGGATCTTGTAGTGTAACTACACGTGCTGATACACCCGCTTTTTCATCAGCCATATTTGCGATAGATGATTCACCAGTAGAAATTAAAATATTTCGCCATTCTTTTTTAGCATTTAGCGTTAAATTAATATTACTTCTCGATTTACTTTCACCACTAGAAAAGTTATATGTGGTACTGGTAACAAACTTAGGATGTGTGTTACGCGTATCATCTTTAAACATTGGAAATGAGTTCAAAAATGACGCCATTGATTCAATACTATTTTGAGTAGAACTCCATGTCGTAATAAGGTCACTGGTTCCCCAAACACTTGATACTAAGTTGAGTGTGAATGTTTTACCTGTGGATGTACTACCTGATATTTCTACAATAAAGGGTTGTAATCCAAATTCTCTTAATAAAACTGAGCCTAAAGATGCATACAACATAACCATTACCATTGGTAAATCTTTTATTTGAGCAAACACCTTTTTAGAGTAACCTTGTAGTGTTCCTTTACTTCGAAAAGAGTCTATTAACTTTTGAAACCCTTTATCATTGCTAAACAACTTGACATTGCTGTCTTTCATTACTTCTTGATAAGGATAAATAAAATAACCTTTCACATGCCCCAAACGCGTTGCAACTTTAACATTTAATGGTGGATTATACCTTTTAGATACATTAATATAGTCAACAAGTTTAGTAGATGTCGACGATGTTACATCTAGCTTTTTATTAACCAATTTCAAGAGTTGACGACTATCTGAAATTTCTTCGGCACTCACAGCTATATTTACTGGCGTTTTATTGTCATAGAAAAGCATATTAAAGCTAACTTCGTTACTCTCAATATCTTCAAAGCGTTCAGTAATTTGAGGGATTGTATTTGTGATAAAAACCTTTTTATCTGGTTCGCCTTCTTTTTTACTTGGTATAAGTTGGTATAAGGCAACACCGCATTGATGATGTTCAATTTCATAGCCTTTCGGTATAATTTCTTGTAAGGCACTATCTTTTTTATTAATTTTTTCAATTTTATCAAGTACATCACTTTTACCTGTTTCCATACAAAGCTCCTTTCTAATTGTTATAGTGTTTATTTAATATCGATTGAAAAGTAGCGTTGATTTCTTGTTCTTTCATAGGTGGTTTACATGCGAATTGTCCCCATAATAAAGCAAATGAATAAACAATATAATCATTAACGTGACATCTCAATAAATGCCCAATTAAGCTAGCTAGTGCATTGTTACGATTGCCTTCGGTTGTTCCAAAGCATAGCTCGCGCCAGTACTCACTATCGCGTCGAGTGTATCCTATGACATTAGGACTAGCATTTGATTGTTCAAACTCCTTCGACCACTGTTCGAGCATATCAACATTCATAATTGGACAGTCATTCACTCGCTTAATAAATATGTGTCCTTTTTGAATAACTGGTAACGCAAAACATCTACTTGGCTGATATGAACCTTCATCCACTTTATGGCCAATTTTATTTGCTAATACTTTTGTATATTTACGATAATCATCTGCACTTATTCGCTCATTCAGAGGGATATATAGGCGTATTCTAGCTTGTTCAGTTGTATGGCTAAACGATGTGTGCCAATACCATGCAACACTGCTTAAAACTGAGCTGATTGCTTCATGTAATTGCTTTAAATCATTTATTTCATCATAATCAAGTACAATCACATCTCTGTATATGACATTAACGTCATTGCGATGCTTTTTTATTGTTTCACCATGATCATTTGCACCGTCTTTAATATCACCGTACACAGCAACACCACGTGCATACTTATAATTCGCTTCTATAGGCACAGACAGTTTATTAACCAACTTACTCCATTCAGGTTTTGAAAAGCTCTTAAATGAACGTGAGTCTAAACTTTCATAATGTACCACTGAAACATGTGTGTCATATTCTAATTTAATTTCATTCATTTTTTGCACCTCTTAATGAAACAACAGAGCAAAGATGTTATAATAAGAATGTGTAATTTCTATATTACTCTGCTACTTTTATTGAATTCTTTGCGTCATCTGATTCCTCGCCAAAGTTCTCAGATGATGCTTTTTCTATTTCATAAAACTTTTCGATAATATTATCGAACTGCTCTATATAGAGATGGAATAAATCAAACATTTGATTATTGTGAATACGTCTCTCATGATAAGAAAATCCCTCTCCAATTAATTCATCTTTATTTAAGACATGATTTGGTTCATATGGATATAGCTCATCAAAATGCCAACCATTACTATCCTTTAAATCCTCAAAACTATCTTTCAACAACTTTAAATCGCTAAATAAATCTTTAATTTCCCGATTCATTTTTATTCTCCTTTCTCTAATTGAAAATTATTCTTTAATTCTTGTGCGCACCATTTCATTATCAATTCTAAGTGCTTTTCACGACTGATCTCTGAAACCACTTCAATACCATTAACATATTCTGTGTGTTCATAACTTTCCAAATTATTCACGACACTTAACTCAAGTTGATAAACCACGTGTTCTATTACTTCTTTTTGTTCATTATTCATTTTCTAATCCTCCTGTTAAATTACATCCTAAAGTTATTAGCCAAGCATAAACGCTAAAAGCAACATACATATTCGATATTGCTAGTAATAAAATTGTTAACAATGAAACTAAGCAAATATAAGTTAAGTACATTTTCATTGCCTTGCCTCCAATAACTTTTTGATATTGACTTGTTTAAAGTCGTTATTCTGGATATTCATATGAGCAGTAAGCTGTTCCATGAATTCATCTACATCAGACTTTTTGAATCTATACGTAGATCCGACCATATAATATTTCATGCCATTATTAATAAGTAATTCTTCAATAGTAGGCTTACTTAAATTCAGATAGTTAGACAACTCTTTGTAAGTCATAAAATATTTCTCTTTCGCTAATTCGTCCACACGTGCATTGATAGCCTGCTCAAGTAACTCACGTGCTTCATCTTCATCAATATTAATGTTGAACATTGGTTTATGCCTCCTTTACTTCAAATTCAAATAATTCATTTACCTCAACTTGTAAAACTTCTGCCATTTTCTTAGCTAATTTAGGGCTTGGAATCTTTTTACCATTAATAATTTGGCTTAAATAAGAAATTCCAACACCTGTTTCACGTGATAAATCAGATAAATTAAAGCCTTTTAAGAACATGGCTTCTTTAAACTTTCTAGTATTCGCTAAAATAGTCATAATTAAAATCCTCCTTCGTTTTTGACTGACTTCTCAATCAATTTATAACTTTATTATACATAATCGTTTTTCTTTTGCAATAGTTTTTCGACTGACTTCTCAATCATTTTTTATTTTTTTGTACATAAACGTCCAAAAAAATGCTATTATTAACATAATTAGGAGGTTTGTAATGATTAGAAATAGATTGTCTGAACTACTGTCAGAAAGAGGACTAAAAATATCTCGTGTTGCAAAAGATGTAAAAATAGCAAGAAGTTCACTTACTTCAATGGCACAAAATGATTCTGAAATGATAAGATATGATGCTATAGATAAATTATGTAGTTATCTGCACATATCTCCTTCAGAATTTTTTGAACATAATCCGATCAATTTTGACTTTACTTTTGATGAAGAACCGAATTATAAAATTAATGATGTTTTCGAGGGATTTGAAGTAACTGCAAACATTACTCACGCTTTTTCGATTGAAAATTTTGACTTTGAAATTTTAGTAGACGTCGAATTAGATAATAGGCAAAAATTAAATTTTGACTTAGACGTCTCATATAAAGAAACTGAAAAGATAACTAATTCACAACATAGATTTATTTTCACGATTAAAAATGAAGATGAAAATATCGGATTAAAAAAATACGTTGATAGTTTATCTGCAGGCCTTAAAAACTTGTTATTTAAAAAAATTAACCAAAAGTTAAGTGGGTATGTTTCTGAAATAATAGTAAAAAATATAGACGATATTGAAGAGCTTTTTCCAAATAAAGGCGAAAAAAGTACGACTCTACATAAAGAAATTTTACAAACTGATAGCCGTTTATCTAGTGATATTTTTAAAGAATATTAATCGAGGTGATCAAATGGCAAGTTATGAAAAACGCGGAAATACATGGCGCTATCGTATATCACTAGGAAAAGACGCAGAAACGGGCAAATATAAATATATTTCAAACTCAGGTTTTAAACGCAAATCAGACGCTAAACATCACGCTGAAATGGTTGAGCGTCAATTAAGAAATGGCGATTATATCGCACCGTCCACATCTACATTTAAACAGGTTGCTGACGATTGGATATCACAATATGCTAACGAAGTAAAAGTAAGTAGTGTCAGAGCACGCGAGAAAGCCATACATCATGCTATAGAACGCTTTAAGAACAAACCAATACAAACTATCAAAAAACACGATTATCAACGTTTTGTAAACGATATAAGCATACAGTATAGCAAGAATTATGTTGATAGCATTGTAACCTCTACAAATATGATATTTAAGTACGCTTATGATATGAAATTAATAAGAATATTGCCTAGCGAGGGTATTAAACGACCTAAAAAGAAAGTTAGTGTGGAAGAATTAGAAGATACTGAGATACATAAAAAGTTTCTTGAAAAAGATGAATTATTTCAATTTCTGGAAATTGCCAAAAATCACCATTCGCCACAAAATAGCTTTGAAGTGTTTTATACATTAGCATATACAGGCATGCGTGCAGGTGAATTATTGGCATTGAAGTGGTCTGATATAGACTTTGAGAATAACACAATCAATATTACAAAGACTTATTACAATCCGAATAACAATAAAAAGCAATATCAAATACTTACGCCAAAAACTGAAAGCTCAATCGGAAAAATTTCAGTTGATCCTCATGTGATTAAATTACTCAAAAATTATAAAGTGGATGTACAGGACACATGGAAAAACGAGTTGTATGTAGATAACAATTTCGTTTTTACTGATGTTAACGGCTATCCCCTCGTAATTAAGAAACTACAGTTATGGATAAAAGCTATACTTAAAAAGACTAACATAACTAATAAACAAATAAGCACTCATTCATTTCGTCATACTCATTGCGCGTTACTTATAGAGGCTGGTGTGCATATTAAGGAAATACAAGAACGCTTGCGACACAAAGATATAAACACCACTATGAACATCTACGCTAAGATTACGAACTCATACAAAAAAGACGCTTCCCAAAAGTTTAGTAAACTCATGGAAAACGTCTCAAAAGATTTATTTTAAAATTTCTATGACCAAATTACGACCACCCAATATTACAAACTTTATAAAATCAGCGTTTAACAGTCGTTTTACATCATTCCCGGCATGCCACCCATGTTAGGTTGGTCATTATTTTTTTCTGGAATTGATGCTACAACCGCTTCAGTCGTTAAGAACATTGCTGCAACACTTGCAGCATGTTGTAATGCTGAGCGTGTTACTTTAGTTGGATCAACGATACCTGCTTCTAACATATTAACCCACTCGTTTGTAGCAGCGTTAAAACCAACACCCGGCTCTGCGTTTTTCAAACGTTCTACAATAACAGAACCTTCTAATCCTGCATTTTCAGCAATTTGACGAACTGGTGCAGTTAGTGCTTTAAGTACAATATTTACACCTGTTTCAATGTCACCTTCTGCTTCAATTTCACTTACTTTTTGGTAAACATTTACTAATGCAGTACCACCACCTGCAACAATACCTTCTTCAACTGCTGCACGTGTAGAATTTAATGCATCTTCAATACGTAATTTACGTTCTTTAAGCTCTGTTTCACTTGCTGCACCTACTTTAATAACTGCAACACCACCTGCTAATTTAGCTAAGCGCTCTTGTAATTTTTCACGATCAAAGTCAGATTCAGTTTCTTCAATTTGAGATTTCAATTGGCTTACACGTGCATCAATGCTGTTTTCGTCACCGTCACCATCAACAACAGTGGTATTATCTTTAGTTACTTCTACTTTACTTGCAGTACCTAACATATCAATTGATGCATCTTTTAAATCTAAGCCTAAATCATCAGTAATCACTTGCGCACCAGTTAAAATAGCTAAATCTTCTAACATTGCTTTACGACGATCACCGAAACCAGGCGCCTTTACTGCAACAGCTGTAAATGTGCCACGCATTCGGTTTAGCACGATATTTGTTAATGCATCGCCTTCAACTTCATCAGCTACAATTAAGATTGGACGATTAGATTGAACCACTTGTTCTAATAAAGGTAAGATATCTTGGAAAGACGAGATTTTCTTATCTGTTACTAAAATGTATGGGCGTTCTAATTCAGCAACCATTTTATCTGAATCAGTAACCATATATGGTGATTGATAACCACGATCAAATTGCATACCTTCAACCACTTCTAGTTCAGTGTTTAGTCCATTTGATTCTTCAATTGTAATGACACCATCGTTACCTACTTTTTCCATAGCTTCAGAAATATAACGTCCAATTTCTTCATCTGCTGCTGAAATCGCACCTACTTGCGCTATTTCATTTTTATTTTCAACTTTTTGAGAATTTTCATGTAATGCTTCTACAGCAACTTTAACTGCTTTGTCGATACCTTGACGTAAACCAACTGGGTTCGCACCACTTGTAACATTTTTCAAGCCTTCTTGAATCATTGCTTGAGCTAATACTGTTGCAGTTGTCGTACCGTCACCAGCAATTTCATTTGTCTTATTTGCAACTTCTTGAACTAGTTTAGCCCCCATATTTTCATATGGATCTTCTAATTCGATTTCTTTAGCAATCGTTACACCATCGTTCGTAATTAAAGGTGCTGTAAACTCTTTATCTAATACAACATTACGTCCTTTAGGACCAATCGTTACTTTAACTGCATTTGCTAATTGGTCTACACCACGTAACATTGCTTGACGTGCATCTTCAGAGAATTTCAATTGTTTAACCATAAATGATAAACCTCCATTTGTTTAGTCATATTTCATTTTCGTTCTTTACAATTTATCTATGAATTTAATTTTATATTATTCAATTACCGCTAAAATATCTTCTTCATTTAATACTAGATATGTTTCATTATCTCGTTTAACTTCTGTACCAGCATATTGTTGGAACACGACACGGTCCCCTTCTTTCACTTCAGGAGTCACTCTTGTACCATCATTTAATAGACGTCCAGTTCCTACTGCAACGATAACGCCTTCGTTTGATTTTTCTTTAGCACTATCAGTTAAAACAATACCACTTTTAGTTGTTTGTTCTTGTTCTTTTTTCTCAATAATCACACGATTTCCAATTGGTTTTAGCAT

Protein sequences of DBSCAN-SWA_5

>NC_002745|1976120:2074317|2069353_2069563_-|WP_001058495.1|DBSCAN-SWA
MNNEQKEVIEHVVYQLELSVVNNLESYEHTEYVNGIEVVSEISREKHLELIMKWCAQELKNNFQLEKGE
>NC_002745|1976120:2074317|2037318_2037936_-|WP_064135358.1|DBSCAN-SWA
MKFERVQKHFKYKTRHIAGCLITHEHGDHAKYTKQFVDNGVISYMTAGTQRAMDFESHRLCTIKAKQELRIGTWSILPFDIEHDANEPVAFLLQSTLGYKVLYVTDTKYLKYKFNGITHMMLEVNYIYEQMQENIKNGSVHSALANRIMESHFSLEHAIGMLKANDLTRLEEIHLIHLSSQNSNAKYIKSEIQKVTGAPVYVGGL
>NC_002745|1976120:2074317|2034400_2034649_-|WP_000178987.1|DBSCAN-SWA
MTMTYNARKEYLNQFFGSKRYLYQDNERVAHIHVVNGTYYFHGHIVPGWQSVKKTFDTAEELEIYIKQHGLEYEEQKQLTLF
>NC_002745|1976120:2074317|2013336_2013489_-|WP_001000058.1|DBSCAN-SWA
MNDSNQGLQANPQYTIHYLSQEITRLTQENAMLKAYIQEQNEKSKSAEEE
>NC_002745|1976120:2074317|2029667_2031329_-|WP_000625088.1|terminase|DBSCAN-SWA
MISNKYVDEYINLWKQGKIILNKERIDLFNYLQKHIYSRDDVYFDEQKIEDCIKFIEKWYFPTLPFQRFIIANIFLIDKNTDEAFFTEFAIFMGRGGGKNGLISAISDFLSTPLHGVKEYHISIVANSEDQAKTSFDEIRTVLMDNKRNKTGKTPKAPYEVSKAKIINRATKSVIRYNTSNTKTKDGGREGCVIFDEIHYFFGPEMVNVKRGGLGKKKNRRTFYISTDGFVREGYIDAMKHKIASVLSGKVKNSRLFAFYCKLDDPKEVDDRQTWEKANPMLHKPLSEYAKTLLSTIEEEYNDLPFNRSNKPEFMTKRMNLPEVDLEKVIAPWKEILATNREIPNLDNQMCIGGLDFANIRDFASVGLLFRKNDDYIWLGHSFVRQGFLDDVKLEPPIKEWEKMGLLTIVDDDVIEIEYIVDWFLKAREKYGLEKVIADNYRTDIVRRAFEDAGIKLEVLRNPKAIHGLLAPRIDTMFAKHNVIYGDNPLMRWFTNNVAVKVKPDGNKEYIKKDENRRKTDGFMAFVHALYRADDIVDKDMSKALDALMSIDF
>NC_002745|1976120:2074317|2000107_2000488_-|WP_000691584.1|DBSCAN-SWA
MKIILKNNSDFPIYEQIKQQVKQNILKGHVAPGEHLPSMRELAKDLQVSLITTKRAYEDLEKDGFVTTIRGKGTFVKEQDSSILKEKQFFTIENLVKELVNEAQAIEMSLEELQDILTFIYEEESS
>NC_002745|1976120:2074317|2054834_2056142_+|WP_001045079.1|DBSCAN-SWA
MNKVHKPLYFYLMLFFSTTIIGALLLYLPFTGKKPISFLDALFIASSAFTVTGLSPVDIGSQFNILGEIVILLLIQIGGLGIVTVTLLTLVFLNRKISMKNRFLIMVTWNIDEPGGVIKLIKHLAIYSLVTELIGMICLCLSFIPKFGIGKGLFLSLFTSVSAFNNAGFALFKNNLIDYSSDPIVIITISILIIFGGIGHFVVIDFINCKKLSKLSLHSKLVLTTTSILIIIGAITFFLLEQFNTMQHMGLVEKIGNSFFQSVTTRTAGFNSIDIASINKSTALMLMLLMFIGGAPLSAAGGIKITTFAVAFIFVLNYIRKENNVSVFNKEISDKHIKLSIVTINISFLFISIITFILSIINPNISLIKLLFEVVSAFGTVGLSMNLTTEYHGITKIIIIFVMLCGKVGLLTLLRTFIPPKSPKNYRYTKGQIYL
>NC_002745|1976120:2074317|2044061_2044277_-|WP_001025404.1|DBSCAN-SWA
MNIQEATKLAMEKGISIRRENQDVYGILPTNLQRYQCLVVSRHYKKKRQTAAGRWQPSADDLIADDWILDY
>NC_002745|1976120:2074317|1994194_1995037_-|WP_000713072.1|DBSCAN-SWA
MKKFFFIGLLVFVVFFTAATIIWFSYDKNKYGTKQYDKTFKDDAFDNVSINLDSTELRIKRGNQFRVKYDGDNDILINIVDKTLKISDKRSKTRGYAIDMNPFHENKKTLTIEMPDKMIKRLNLSSGAGSVRISDVDLENTSIQSINGEVVIKNSNLDALDSKTNNSSTYISKSNIKNSNIKVVIGTLQIDKSQIKQSIFLNDHGDIEFKNMPSKVDAKASTKQGDIRFKYDSKPEDTILKLNPGTGDSVVKNKTFTNGKVGKSDNVLEFYTIDGNIKVE
>NC_002745|1976120:2074317|2000745_2000922_-|WP_000681968.1|DBSCAN-SWA
MKHLTKIFVVLAIILFIIGYYLQATNHESQGIKLLLAAIMFMICAFISRSNDRRKNSK
>NC_002745|1976120:2074317|2041824_2041986_-|WP_000048129.1|DBSCAN-SWA
MSKTYKSYLVAVLCFTVLAIVLMPFLYFTTAWSIAGFASIATFIFYKEYFYEE
>NC_002745|1976120:2074317|2001462_2002749_+|WP_001068542.1|DBSCAN-SWA
MNPLAQSLNEQLQQSNATAFTMLSDLGQNMFYPKGILSQSAEAKSTTYNATIGMATNKDGKMFASSLDAMFNDLTPDEIFPYAPPQGIEELRDLWQQKMLRDNPELSIDNMSLPIVTNALTHGLSLVGDLFVNQGDTILLPEHNWGNYKLVFNTRNGANLQTYPIFDKDGHYTTDSLVEALQSYNKDKVIMILNYPNNPTGYTPTHKEVTTIVDAIKALADKGTKVIAVVDDAYYGLFYEDVYTQSLFTALSNLNSNAILPVRLDGATKEFFAWGFRVGFMTFGTSDQTTKEVLEAKVKGLIRSNISSGPLPTQSAVKHVLKNNKQFDKEIEQNIQTLKERYEVTKEVVYADQYHSHWQAYDFNSGYFMAIKVHDVDPEELRKHLIEKYSIGVIALNATDIRIAFSCVEKEDIPHVFDSIAKAIDDLR
>NC_002745|1976120:2074317|2074032_2074317_-|WP_000917289.1|DBSCAN-SWA
MLKPIGNRVIIEKKEQEQTTKSGIVLTDSAKEKSNEGVIVAVGTGRLLNDGTRVTPEVKEGDRVVFQQYAGTEVKRDNETYLVLNEEDILAVIE
>NC_002745|1976120:2074317|2038016_2038937_-|WP_000180600.1|DBSCAN-SWA
MTNELLLKNNKMGDNVLSRVKTLEAQGDLQFPANYSPENAMKSAMLQLQELKGSKKDGYKPALEFATSTSIANALMDMVVQGLNPAKNQGYFIMYGDKVQFQRSYHGTMAVTKRVAGAEEINAEVIFEGDEVKYKTKNGKIVELEHTQSFGNRNTQNIIGAYATVVFKDESRNYTEIMTFEEIEEAWKQSQMVYNGVFKEDGTHRRFPQEMAKKTVINRACKKILNSTDDASLLSNQIKESEQRQRKEVLDAEVEENANQEQLDFEPPVFEEAQYTELENEKPIDVSDFEEIKEPATEKESEEEPF
>NC_002745|1976120:2074317|2064248_2064590_-|WP_001190615.1|DBSCAN-SWA
MQSIAEKETYHLPTEHLQVFNVIKNTSNKYITKTKILNQLGYEYNSSNERWLRRVINSLVYDYGYPIGCSYKPSERGYYIITTEQEKQQAMRSIKKLADGSMKRYEALKRIKV
>NC_002745|1976120:2074317|2027743_2028481_-|WP_000642728.1|protease|DBSCAN-SWA
MKAEIKGVIVSNEDKWVYEMLGMDSTCPKDVLTQLEFSDEDVDIIINSNGGNLVAGSEIYTHLRAHKGKVNVRITAIAASAASLIAMAGDHIEMSPVARMMIHNPSSIAQGEAKDLNHAAETLEHVGQIMAEAYAVRAGKNKQELVEMMARETWLNADEAIEQGFADSKMFENDNMQIVASNTQVLSKDVLNRVTALVSKTPEVNIDIDAIANKVIEKINMKEKESEIDVADSKVSANGFSRFLF
>NC_002745|1976120:2074317|2046356_2046698_+|WP_000591749.1|DBSCAN-SWA
MIKKIFTKKHVFLVIEDENHNHSDAVFGKSILLSIYVGVNKKTNSKSGKFIYLDRSKRIVRQSDITKIESANENDVDFYNLLKKEKEIVYSKNIVDKYNLANYIIYYEVSTKE
>NC_002745|1976120:2074317|1982525_1983320_+|WP_001177828.1|DBSCAN-SWA
MQLYYLGPKGTFSYLACRQYFSENEATFQPKSNLFEVIKAVADDDTSIGVVPIENSIEGTINIVADALAQQDVFAHGEIRLDINFALYGNGTDSISDIKKVYSIAPAISQTTNYIHQHQFDYDYVDSTIQSLTKIENGVAAIAPLGSGEAYGFTPIDTHIEDYPHNVTRFLVIKNQQQFDQNATSLMFLITPMHDKPGLLASVLNTFALFNINLSWIESRPLKTQLGMYRFFVQADSAITTDIKKVIAILETLDFKVEMIGAFN
>NC_002745|1976120:2074317|2010840_2010948_+|WP_031762631.1|DBSCAN-SWA
MIFILWCVNLYIEKGQHAQTCYPSEPVKKTVAILD
>NC_002745|1976120:2074317|2041427_2041730_-|WP_000165371.1|DBSCAN-SWA
MTKNYKDMTQEEIKDLLSEKTAELYELAKEIKGESKFDILLFSSIGVIDGDYLAGSSSVIGHTFDLAYLLDSTKSYKDIVNVLQMCKSQKILGIDDDKED
>NC_002745|1976120:2074317|2042360_2042741_+|WP_000762521.1|DBSCAN-SWA
MKLDHDCVRHLLLEIETNKKIGEPLTEYNFKDNVVFGKYDFETVMYALLKLEEAKYVSVKFGWEDGHIYGYTINDITWSGHEFLDNIRDNHTWKEVKKVANKTTSMSVTLLSKLAFNYLTQKFNLT
>NC_002745|1976120:2074317|2072340_2073957_-|WP_000240642.1|DBSCAN-SWA
MVKQLKFSEDARQAMLRGVDQLANAVKVTIGPKGRNVVLDKEFTAPLITNDGVTIAKEIELEDPYENMGAKLVQEVANKTNEIAGDGTTTATVLAQAMIQEGLKNVTSGANPVGLRQGIDKAVKVAVEALHENSQKVENKNEIAQVGAISAADEEIGRYISEAMEKVGNDGVITIEESNGLNTELEVVEGMQFDRGYQSPYMVTDSDKMVAELERPYILVTDKKISSFQDILPLLEQVVQSNRPILIVADEVEGDALTNIVLNRMRGTFTAVAVKAPGFGDRRKAMLEDLAILTGAQVITDDLGLDLKDASIDMLGTASKVEVTKDNTTVVDGDGDENSIDARVSQLKSQIEETESDFDREKLQERLAKLAGGVAVIKVGAASETELKERKLRIEDALNSTRAAVEEGIVAGGGTALVNVYQKVSEIEAEGDIETGVNIVLKALTAPVRQIAENAGLEGSVIVERLKNAEPGVGFNAATNEWVNMLEAGIVDPTKVTRSALQHAASVAAMFLTTEAVVASIPEKNNDQPNMGGMPGMM
>NC_002745|1976120:2074317|2028464_2029652_-|WP_000025274.1|portal|DBSCAN-SWA
MSILEKIFKTRKDITYMLDLDMIEDLSQQAYVKRLAIDSCIEFVARAVAQSHFKVLEGNRIQKNDVYYKLNIKPNTDLSSDSFWQQVIYKLIYDNEVLIVVSDSKELLIADSFYREEYALYDDIFKDVTVKDYTYQRTFTMQEVIYLKYNNNKVTHFVESLFEDYGKIFGRMIGAQLKNYQIRGILKSASSAYDEKNIEKLQAFTNKLFNTFNKNQLAIAPLIEGFDYEELSNGGKNSNMPFSELSELMRDAIKNVALMIGIPPGLIYGETADLEKNTLVFEKFCLTPLLKKIQNELNAKLITQSMYLKDTRIEIVGVNKKDPLQYAEAIDKLVSSGSFTRNEVRIMLGEEPSDNPELDEYLITKNYEKANSGENDEKEKDENTLKGGDEDESGD
>NC_002745|1976120:2074317|2031325_2031670_-|WP_000402904.1|DBSCAN-SWA
MEIIVDENLVLKEKERLQVLYKDIPSNKLKVVDGLIIQAARLRVMLDYMWEDIKEKGDYDLFTQSEKAPPYERERPVAKLFNARDAAYQKIIKQLSDLLPEEKEDTETPSDDYL
>NC_002745|1976120:2074317|2011379_2012153_-|WP_025174055.1|DBSCAN-SWA
MKKTTFILLSFIALTLITSPFVNCSEKSEEINGKDLQKKSELQGTALSNLRQTYYHNGSAIIENKESNDQFLKNTILFNDFFTGHQWYNDLLVDLGSKDTANIYKGKKVDLYGVYYGYQCTGGTPFKTACMYGGVTLHDNNQLEEEKKVPINLWIDGKQNTVPLGTVKTNKKEVTVQELDLQSRHYLHETYNLYNTDAFNGKIQRGLIEFHPSSGDSVGYDLFGAQGQYPDTQLRIYRDNKTIKSKNMHIDIYLYTT
>NC_002745|1976120:2074317|2003332_2004763_-|WP_001557458.1|DBSCAN-SWA
MKFKSLITTTLALGVIASTGANFNTNEASAAAKPLDKSSSTLHHGHSNIQIPYTITVNGTSQNILSSLTFNKNQNISYKDIENKVKSVLYFNRGISDIDLRLSKQAEYTVHFKNGTKRVIDLKSGIYTADLINTSDIKAISVNVDTKKQPKDKAKANVQVPYTITVNGTSQNILSNLTFNKNQNISYKDLEGKVKSVLESNRGITDVDLRLSKQAKYTVNFKNGTKKVIDLKSGIYTANLINSSDIKSININVDTKKHIENKAKRNYQVPYSINLNGTSTNILSNLSFSNKPWTNYKNLTSQIKSVLKHDRGISEQDLKYAKKAYYTVYFKNGGKRILQLNSKNYTANLVHAKDVKRIEITVKTGTKAKADRYVPYTIAVNGTSTPILSKLKISNKQLISYKYLNDKVKSVLKSERGISDLDLKFAKQAKYTVYFKNGKKQVVNLKSDIFTPNLFSAKDIKKIDIDVKQYTKSKKK
>NC_002745|1976120:2074317|2013003_2013291_-|WP_001262621.1|DBSCAN-SWA
MANEIIKKTERFILVQIDKEGTERVLYQDFVGSFTTSDSASYAQDFKSEENAKKIAETLNLLYQLTGNQNGVKVVKEVVDRTDLSSDKSVDSETM
>NC_002745|1976120:2074317|2036847_2037318_-|WP_000934759.1|DBSCAN-SWA
MLNRTILVGRLTRDPELRTTQSGVNVASFTLAVNRTFTNAQGEREADFINIIVFKKQAENVNKYLSKGSLAGVDGRLQTRNYENKEGQRVYVTEVIADSIQFLEPKNSNDTQQDLYQQQVQQTRGQSQYSNNKPVKDNPFANANGPIEIDDNDLPF
>NC_002745|1976120:2074317|2034645_2034903_-|WP_000111491.1|DBSCAN-SWA
MSVISNRKVDMNEIQDNVKQPAHYTYGDIEIIDFIEQVTAQYPPQLAFAIGNAIKYLSRAPLKNGHEDLAKAKFYVQRAFDLWEQ
>NC_002745|1976120:2074317|1977317_1977644_+|WP_000434933.1|DBSCAN-SWA
MEQIELFSIDKFKCNSEAKYYLNIIEGEWHPQDLNDSPLKFILSTSDDSDYICKYINTEHKQLTLYNKNNSSIVIEIFIPNDNKILLTIMNTEALGTSPRMTFIKHKS
>NC_002745|1976120:2074317|1996295_1996859_+|WP_000182842.1|DBSCAN-SWA
MTNLETYFKNSQPLNEYIDGMKTNQDTVLSIYQSFELPEDDSRIKKIKEMNYSKVLVITEDWCGDAMMNLPILKHISEALNLEVRVFHRDDDTKLIDQYLTNGKSRAIPIFVFLNDQFEQETVWGPRANEVQKFVTDVRADKLPSKDHPDYADLEKETHLVISNRYKTDASFWKAVYNSILNKLENK
>NC_002745|1976120:2074317|2026270_2026555_-|WP_000238236.1|DBSCAN-SWA
MVKFKVVRAFKDIEHNQHKYKVGELYPAEGYNNPRVELLTNQIKNKYDKVYIVPLDKLTKQELLELCESLQKKASSSMVKSEIVDLLNGEDNDD
>NC_002745|1976120:2074317|2034140_2034386_-|WP_001065108.1|DBSCAN-SWA
MNNREQIEQSVISASAYNGNDTEGLLKEIEDVYKKARAFDEILDGMTNAIQHSVKEGIELDEAVGIMAGQVIYKYEEEQGK
>NC_002745|1976120:2074317|2046901_2047084_+|WP_000694772.1|DBSCAN-SWA
MKIKNCKIKKETIVYEVLTSGNQPFTYELPKDLSSHNARKYLEFISQKLDGDKLTKEDSL
>NC_002745|1976120:2074317|2068090_2068960_-|WP_001002689.1|DBSCAN-SWA
MNEIKLEYDTHVSVVHYESLDSRSFKSFSKPEWSKLVNKLSVPIEANYKYARGVAVYGDIKDGANDHGETIKKHRNDVNVIYRDVIVLDYDEINDLKQLHEAISSVLSSVAWYWHTSFSHTTEQARIRLYIPLNERISADDYRKYTKVLANKIGHKVDEGSYQPSRCFALPVIQKGHIFIKRVNDCPIMNVDMLEQWSKEFEQSNASPNVIGYTRRDSEYWRELCFGTTEGNRNNALASLIGHLLRCHVNDYIVYSFALLWGQFACKPPMKEQEINATFQSILNKHYNN
>NC_002745|1976120:2074317|2042940_2043693_-|WP_001148605.1|DBSCAN-SWA
MQALQTKSNIGEMFNIQEKENGEIAISGRELHQALEVKTPYKKWFERMSDYGFEENIDYIVTDIFVHNPLGGRQNQTDHALTLDTAKEIAMIQRSEPGKRARQYFIQVEKAWNSPEMIMQRALKIANNTINQLETKIERDKPKIVFADAVATTKTSILVGELAKIIKQNGINIGQRRLFEWLRQNGFLIKRKGVDYNMPTQYSMERELFEIKETSITHSDGHTSISKTPKVTGKGQQYFVNKFLGEKQTS
>NC_002745|1976120:2074317|2025650_2026013_-|WP_000755150.1|head,tail|DBSCAN-SWA
MKKVFKKPRITTKRLNTRVHFYKYTENNGPEAGEKEEKLLYSCWASIDGVWLRELEQAISNGTQNDIKLYIRDPQGDYLPSEEHYLEIESRYFKNRLNIKQVSPDLDNKDFIMIRGGYSS
>NC_002745|1976120:2074317|2010534_2010789_-|WP_000611512.1|holin|DBSCAN-SWA
MINWKIRMKQKSFWVAILSAIFLFAQNIAKAIGYDIQVYTEQLTDGLNAILGFLVLTGVIQDPTTKGIGDSHQALEYEEPRRKY
>NC_002745|1976120:2074317|2032776_2032977_-|WP_001557462.1|DBSCAN-SWA
MWITMTIVFAILLLVCISINSDHAREIQALRYMNDYLLDEVVKTKGYNGLEEYRIELKRINNDIKK
>NC_002745|1976120:2074317|2044689_2045403_+|WP_001031454.1|DBSCAN-SWA
MNKERNIIIAKNIRKFLNDSNMSQKKLAELINIKPSTLSDYLNLRSNPSHGVIQRIADVFEVGKSDIDTTYKDDNDITSIYNKLTPPRQENVLNYANEQLEEQNSKGDNVVDINSYKQEKTPVNVNGCVSAGVGERLHDETLFTEMVKGPIPTHDLALKVNGDSMEPMFKDGEIIFVEKTHNIKNGQIGIFIIEEEAYVKKVFVEDDRLTLVSLNKDYDDLHFYRNESVRLIGKVIL
>NC_002745|1976120:2074317|2069024_2069351_-|WP_001078344.1|DBSCAN-SWA
MNREIKDLFSDLKLLKDSFEDLKDSNGWHFDELYPYEPNHVLNKDELIGEGFSYHERRIHNNQMFDLFHLYIEQFDNIIEKFYEIEKASSENFGEESDDAKNSIKVAE
>NC_002745|1976120:2074317|2034902_2035274_-|WP_000101279.1|DBSCAN-SWA
MARKARIVTINDKPYRFSKFEMELIESHGITAGMVSKRVKDGWELHEAMDAPEGTRLSEYREKKTIERLEQARLERKLERKRKREAELRRKKPHLFNVPQKHSRDPYWFDNTYNQMFKKWSEA
>NC_002745|1976120:2074317|2001164_2001263_-|WP_000990056.1|DBSCAN-SWA
MMWWQEGMMTLITGGLLIIFRLWLELKWKNKK
>NC_002745|1976120:2074317|2061075_2061780_+|WP_001035599.1|DBSCAN-SWA
MNKKLLMNFFIVSPLLLATIATDFTPVPLSSNQIIKTAKASTNDNIKDLLDWYSSGSDTFTNSEVLDNSLGSMRIKNTDGSISLIIFPSPYYSPAFTKGEKVDLNTKRTKKSQHTSEGTYIHFQISGVTNTEKLPTPIELPLKVKVHGKDSPLKYWPKFDKKQLAISTLDFEIRHQLTQIHGLYRSSDKTGGYWKITMNDGSTYQSDLSKKFEYNTEKPPINIDEIKTIEAEIN
>NC_002745|1976120:2074317|2033607_2034144_-|WP_000185693.1|DBSCAN-SWA
MTNTLTIDQLQELLQIQKKFDDRIPTRNLNDTVASMIIEFAEWVNTLEFFKNWKKQPGKPLDTQLDEIADYLAFSLQLTLTIVDEEDLEETTEVMVDLIENEVTLPKLHSVYFVHVMHTLTEQFVKGIDNSIVQVLIMPFLYANTYYTIDQLIDAYKKKMKRNHERQDGTADAGKGYV
>NC_002745|1976120:2074317|2042727_2042925_-|WP_001148856.1|DBSCAN-SWA
MQAQNKKVIYYYYDEECNRRPVNIQYNDGYDLMIDQRFIEMTLERHPHLKNNFYGLIDGKEFKLD
>NC_002745|1976120:2074317|2025996_2026281_-|WP_000150936.1|head,tail|DBSCAN-SWA
MTIDDLLVKFKSLEKIDHNSEDEYLKQLLKMSYERIKNQCGVFELENLIGQELILIRARYAYQDLLEHFNDNYRPEIIDFSLSLMEVSEDEESV
>NC_002745|1976120:2074317|2040890_2041154_-|WP_001205732.1|DBSCAN-SWA
MRDTERNILNIFKTLFDEYTLSNQRALLEIERNHHGYLSINFLHYHDSYKTNNKLVQIHEINPDSHERIKNLIIEVLRGHRKIKKGA
>NC_002745|1976120:2074317|2023934_2024159_-|WP_071621395.1|DBSCAN-SWA
MPDSIKTLKVGDTYDLNVVVEPSNQSKLLKYTTDQTNIVSINSDGQVTAEAQGIATVKATVGNMSDTITINVEA
>NC_002745|1976120:2074317|2047183_2048167_+|WP_001558608.1|DBSCAN-SWA
MKKVSVIMPTFNNGEKLHRTISSVLNQTMKSTDYELIIIDDHSNDNGETLNVIKKYKGLVRFKQLKKNSGNASVPRNTGLKMSKAEYVFFLDSDDLLHERALEDLYNYGKENNSDLIIGKYGVEGKGRSVPKAIFEKGNVAKADIIDNSIFYALSVLKMFKKSVIDKNKIKFKTFSKTAEDQLFTIEFLMNSKNYSIKTDYEYYIVVNDFESSNHLSVNKSTGNQYFATINEIYKAIYKSPIYKNQEKRHQLAGKYTTRLLRHGQKKNFANSKMKYEDKIEWLNNFSKTINKVPRDSDKYVTQIFNLKLEAIRQNDLLAVMIADKLL
>NC_002745|1976120:2074317|2063658_2064237_-|WP_000846280.1|DBSCAN-SWA
MKTESYFKEYNQFVIDQQKAIQELEQERNALESKIKIDKSTYKQLIMDGQDDKADNLYQATDADEKKLKALNKRLETKKSVSKEVKYQKTIELLKHQSELSSLYESEKQSALGKLKKVVDAYNEIIDEIEDINDRYEDEHQQYASIYSQEQLYDDKEAREALNGYFRENIFTSYINGNDLPYEHNNKLFLKR
>NC_002745|1976120:2074317|1992473_1992647_-|WP_000267034.1|DBSCAN-SWA
MWNFIKCVFKFVFSLVAITTLVAGVGVVAFAYIFKKDFEDIERKTKEIISDIESKNN
>NC_002745|1976120:2074317|1990201_1991230_-|WP_000181315.1|DBSCAN-SWA
MTNGYIGSYTKKNGKGIYRFELNENQSRIDLLEIGFELEASTYLVRNNEVLYGINKEGEQCGVASLKIDDNGELHLLNKCLSSKAGTGCYVSISEDKRYLFEAVYGAGIIRMYELNTHTGEIIRLIQELAHDFPTGTHERQDHPHAHYINQTPDGKYVAVTDLGADRIVTYKFDDNGFEFYKESLFKDSDGTRHIEFHDNGKFAYVVHELSNTVSVAEYNDGKFEELERHLTIPENFDGDTKLAAVRLSHDQQFLYVSNRGHDSIAIFKVLDNGQHLELVTITESGGQFPRDFNIASSDDLLVCAHEQGDSVVTVFERSKETGKITLCDNTRVASEGVCVIF
>NC_002745|1976120:2074317|2009085_2009577_-|WP_000920042.1|DBSCAN-SWA
MLKRSLLFLTVLLLLFSFSSITNEVSASSSFDKGKYKKGDDASYFEPTGPYLMVNVTGVDSKGNELLSPHYVEFPIKPGTTLTKEKIEYYVEWALDATAYKEFRVVELDPSAKIEVTYYDKNKKKEETKSFPITEKGFVVPDLSEHIKNPGFNLITKVVIEKK
>NC_002745|1976120:2074317|2017279_2018764_-|WP_000567396.1|tail|DBSCAN-SWA
MIDTIKVNNKTIPWLYVERGFEIPSFNYVLKTENVDGRSGSIYKGRRLESYSFDIPLVVRNDYLSHNGIKTHDDVLNELVKFFNYEEQVKLQFKSKDWYWNAYFEGPIKLHKEFAIPVKFTIKVVLTDPYKYSVTGNKNTAISDQVSVVNSGTADTPLIVEARAIKPSSYFMITKNDEDYFMVGDDEVTKEVKDYMPPVYHSEFRDFKGWTKMITEDIPSNDLGGKVGGDFVISNLGEGYKATNFPDAKGWVGAGTKRGLPKAMTDFQITYKCIVEQKGKGAGRTAQHIYDSDGKLLASIGYENKYHDRKIGHIVVTLYNQKGDPKKIYDYQNKPIMYNLDRIVVYMRLRRVGNKFSIKTWKFDHIKDPDRRKPIDMDEKEWIDGGKFYQRPASIIAIYSAKYNGYKWMEMNGLGSFNTEILPKPKGARDVIIQKGDLVKIDMQAKSVVINEEPMLSEKSFGSNYFNVDSGYSELIIQPENVFDTTVKWQDRYL
>NC_002745|1976120:2074317|2006214_2006475_+|WP_001791826.1|DBSCAN-SWA
MCIVIYLIYSLIVYFICIINFFIMAAPFLMTNADYVWTPMTTVTLFILSLIIFLIFIKTKDVVHLTIFILNLLFSILYCLPILFYL
>NC_002745|1976120:2074317|2023534_2023885_-|WP_001096355.1|DBSCAN-SWA
MAKLKRNIIQLVEDPKANEIKLQTYLTPHFISFEIVYEAMDLIDDIEDENSTMKPREIADRLMDMVVKIYDNQFTVKDLKERMHAPDGMNALREQVIFITQGQQTEETRNFIQNMK
>NC_002745|1976120:2074317|2024200_2024845_-|WP_000268740.1|tail|DBSCAN-SWA
MAVKHASAPKAYINITGLGFAKLTKEGAELKYSDITKTRGLQKIGVETGGELKTAYADGGPIESGNTDGEGKISLQMHAFPKEIRKIVFNEDYDEDGVYEEKQGKQNNYVAVWFRQERRDGTFRTVLLPKVMFTNPKIDGETAEKDWDFSSEEVEGEALFPLVDNKKSVRKYIFDSANMTNHDGDGEKGEEAFLKKILGEEYTGNVTEGNEETL
>NC_002745|1976120:2074317|2024845_2025253_-|WP_000565498.1|DBSCAN-SWA
MIDILYKVHEVISQDRIIREHVNINNIKFNKYPNVKDTDVPFIVIDDIDDPIPTTYTDGDECAYSYIVQIDVFVKYNDEYNARIIRNKISNRIQKLLWSELKMGNVSNGKPEYIEEFKTYRSSRVYEGIFYKEEN
>NC_002745|1976120:2074317|2050638_2051655_-|WP_000595392.1|DBSCAN-SWA
MIKQLYKNITICSLAISTALTVFPATSYAKINSEIKAVSEKNLDGDTKMYTRTATTSDSQKNITQSLQFNFLTEPNYDKETVFIKAKGTIGSGLRILDPNGYWNSTLRWPGSYSVSIQNVDDNNNTNVTDFAPKNQDESREVKYTYGYKTGGDFSINRGGLTGNITKESNYSETISYQQPSYRTLLDQSTSHKGVGWKVEAHLINNMGHDHTRQLTNDSDNRTKSEIFSLTRNGNLWAKDNFTPKDKMPVTVSEGFNPEFLAVMSHDKKDKGKSQFVVHYKRSMDEFKIDWNRHGFWGYWSGENHVDKKEEKLSALYEVDWKTHDVKFVKVLNDNEKK
>NC_002745|1976120:2074317|1981429_1982506_+|WP_000897635.1|DBSCAN-SWA
MLFKEAQAFIENMYKECHYETQIINKRLHDIELEIKETGTYTHTEEELIYGAKMAWRNSNRCIGRLFWDSLNVIDARDVTDEASFLSSITYHITQATNEGKLKPYITIYAPKDGPKIFNNQLIRYAGYDNCGDPAEKEVTRLANHLGWKGKGTNFDVLPLIYQLPNESVKFYEYPTSLIKEVPIEHNHYPKLRKLNLKWYAVPIISNMDLKIGGIVYPTAPFNGWYMVTEIGVRNFIDDYRYNLLEKVADAFEFDTLKNNSFNKDRALVELNYAVYHSFKKEGVSIVDHLTAAKQFELFERNEAQQGRQVTGKWSWLAPPLSPTLTSNYHHGYDNTVKDPNFFYKKKESNANQCPFHH
>NC_002745|1976120:2074317|2006527_2006878_-|WP_000702262.1|DBSCAN-SWA
MKIRKSILAGTLAIVLASPLVTNLDKNEAQASTSLPTSNEYQNEKLANELKSLLDELNVNELATGSLNTYYKRTIKISGLKAMYALKSKDFKKMSEAKYQLQKIYNEIDEALKSKY
>NC_002745|1976120:2074317|1993097_1994138_+|WP_001188043.1|DBSCAN-SWA
MQQVISDIMTFRGSHFELGVKTGKWLQQTPLLKNREKEWKKRVPRFDIDVNETYQIFQTYAPQIWEELMGLQSILKMPTRQIILNFGHYRFTDLKESGCTVFQGKDFMVRNYDYHPATYDGRYLLYQPTDSGLAQIGPVSRVTGRMDGMNESGLTMGYNFMHRKKPANGFVCYMIGRLILENCRNVTEAIQLLKEIPHRSSFSYILMDKSLNHAIVEVTPRSIDVRYDNICTNHFEILTHENRNYTKESKERLARTISQTNDNLDMTTAFKLFNNPQYEIYSKLFKSWSGTIHTSMYQPETLTAYFTLGENAPPEIIDFKSWLDGQDLNITHFTGNIDTDLTFANK
>NC_002745|1976120:2074317|1999214_2000111_-|WP_000991306.1|DBSCAN-SWA
MNAIELSNVNYSSDQFNLKNISFKVPQGFVTGFIGRNGAGKTTIIRLIMDLYQPQTGVIRVLEEDMALNPIELKNSIGFVYSENYFNERWTTKQLEKMIAPFYRKWDHQVFEFYLEKFDLPINKSIKTFSTGMKMKLSLAVAFSHHAELYIFDEPTSGLDPLARNELLEIIQQELIDENKTIFMSTHIISDLEKIADYIIHLSDGEVILNGSKEQLLQRYQVVSGATEDLDDELASLLIYEEHKRTGFIGLTEHAQVFKEILGHKVNITTPSIENLMVYLEKRKPKYHENIKLMEEGF
>NC_002745|1976120:2074317|2041982_2042306_-|WP_001120201.1|DBSCAN-SWA
MPHILNVTVPIPETHVLITKDEYEELIAYSLDPVWNMSDLKKKLKIASDETIKDRLLFHPRLEKELRAQGIVHYPDENFNRWRFNARRMHKFVDEHFNEIYKGGHNK
>NC_002745|1976120:2074317|2048482_2049520_+|WP_000857180.1|integrase|DBSCAN-SWA
MKTRCYDGKKWQYEFKHEGKRYRKKGFRTKREANSAGLDKLNELRSGFNIDNYITLEEYFENWIKTYKQPVVKENTYRHYRNALQHIQKHKIGKMELSKINRQVYQKFINDHSKEHAKETIRKTNGAIRSALDDALYDGLIFKNPAYKVNYKAGKPTKSEQEKFISVTEYEILKDHVRKKRTRSSLALFIMICTGCRVSGARNIKIEHINQVKNTIFIDERKTDTSPRYISIAKSDMKHIMDVISTFAISYDGYIFKEAGSIINLQAINNALKSACRVNNIPIITSHALRHTHCSYLLAKGVSIHYISKRLGHKNIAITTSVYSHLLEEKFNEEDKKTTKILESM
>NC_002745|1976120:2074317|2013481_2017264_-|WP_000582152.1|DBSCAN-SWA
MIHVLDFNDKIIDFLSTDDPSLVRAIHKRNVNDNSEMLELLISSERAEKFRERHRVIIRDSNKQWREFIINWVQDTMDGYTEIECIASYLADITTAKPYAPGKFEKKTTSEALKDVLSDTGWEVSEQTEYDGLRTTSWTSYQTRYEVLKQLCTTYKMVLDFYIELSSNTVKGRYVVLKKKNSLFKGKEIEYGKDLVGLTRKIDMSEIKTALIAVGPENDKGKRLELVVTDDEAQSQFNLPMRYIWGIYEPQSDDQNMNETRLSSLAKTELNKRKSAVMSYEITSTDLEVTYPHEIISIGDTVRVKHRDFNPPLYVEAEVIAEEYNIISENSTYTFGQPKEFKESELREEFNKRLNLIHQKLNDNISNINTIVKDVVDGELEYFERKIHKSDTPPENPVNDMLWYDTSNPDVAVLRRYWNGRWIEATPNDVEKLGGITREKALFSELNNIFINLSIQHASLLSEATELLNSEYLVDNDLKADLQASLDAVIDVYNQIKNNLESMTPETATIGRLVDTQALFLEYRKKLQDVYTDVEDVKIAISDRFKLLQSQYTDEKYKEALEIIATKFGLTVNEDLQLVGEPNVVKSAIEAARESTKEQLRDYVKTSDYKTDKDGIVERLDTAEAERTTLKGEIKDKVTLNEYRNGLEEQKQYTDDQLSDLSNNPEIKASIEQANQEAQEALKSYIDAQDDLKEKESQAYADGKISEEEQRAIQDAQAKLEEAKQNAELKARNAEKKANAYTDNKVKESTDAQRKTLTRYGSQIIQNGKEIKLRTTKEEFNASKRTLSRLLADITVNAMKGIYLRYDENGAITSHTIDKDGVKISGDKVDITANREFNVVANNINNKVGKNDIVNSLNLSNEGLDINVNRIGIKGGNANRYVQVQNDFIELGGIVQRTWKGKRSTDDIFTRLKDGHLRFRNNTAGGSLYMSHFGISTYIDGEGEDGGSSGTIQWWDKTYSDSGMNGITINSYGGVVALTSDYNRIIIDSYASANIESREAPIYLSPNTKNKPGLNRFAFTLSNADSAYETDGYIMFGSDENYKYGAGLRFSKRSNKGLVQVVNGDYATGGDTTIESGMGKFNLVKRRDGNSYVSIQSYDLLAVGSDNAGDRVASNSIYKRTYSAPANLHITSAGTIGRATSAKKYKISIENQYINEDDQFSHSKEILKLPIRTWFDKYESEIMAKELESGKKLSDDTFKLSRHTGLIAEEVEELGFNEFVIYDDNGEIEGIAYDRLWVHLIPIIKNQQSKIEKLEELINE
>NC_002745|1976120:2074317|1983391_1983499_+|WP_001802312.1|DBSCAN-SWA
MVDFLLFVLFLHDAAVYVSLPLVQAIANVTFYFSF
>NC_002745|1976120:2074317|1986742_1987303_+|WP_000149686.1|DBSCAN-SWA
MTHRALLVVDYSYDFIADDGLLTCGKPGQNIEDFIVSRINDFNYYQDHIFFLMDLHYLHDIHHPESKLFPPHNIVDTSGRELYGKVGKLYETIKAQPNVHFIDKTRYDSFFGTPLDSLLRERSINQVEIVGVCTDICVLHTAISAYNLGYKISVPAEGVASFNQKGHEWALAHFKNSLGAEVEQHV
>NC_002745|1976120:2074317|2058049_2058850_-|WP_000278088.1|DBSCAN-SWA
MYKRLFISRVILIFALILVISTPNVLAESQPDPMPDDLHKSSEFTGTMGNMKYLYDDHYVSATKVKSVDKFLAHDLIYNISDKKLKNYDKVKTELLNEDLAKKYKDEVVDVYGSNYYVNCYFSSKDNVGKVTGGKTCMYGGITKHEGNHFDNGNLQNVLVRVYENKRNTISFEVQTDKKSVTAQELDIKARNFLINKKNLYEFNSSPYETGYIKFIENNGNTFWYDMMPAPGDKFDQSKYLMMYNDNKTVDSKSVKIEVHLTTKNG
>NC_002745|1976120:2074317|2005720_2005900_+|WP_000669789.1|DBSCAN-SWA
MKFKTTKECKSNNIFKRSQEINNRESEKGCLWGISMLILLFLLILFGITACSSSIHFIN
>NC_002745|1976120:2074317|1995650_1996175_-|WP_000966288.1|DBSCAN-SWA
MLYLNKYKERVTSVRIQNRWVVFILFLICSFGVLIGLYQYRHTKTVDLSNLEINDIKLNEKFDKKGYEVNKKIKFDRFKFYNSKAHPDLTVKVREKDNIVKGIILVRDEKIHTNFDGGIGSPINNAIENLGFGYKRTKVGNDFSSVKYIDRDNHLKLNLLYQDLEIKRIEFFSK
>NC_002745|1976120:2074317|1977935_1978109_-|WP_000669862.1|DBSCAN-SWA
MKFKVNENETIADCLSRMKMQGYMPVKRIEKPVFQEQKDGTVEVSHQEIVFVGKKIQ
>NC_002745|1976120:2074317|1997664_1998537_-|WP_000763043.1|DBSCAN-SWA
MKLEHITKKYGSNVVLNDIDFDFGDSRIVGLIGKNGVGKTTIMKVMNGNIIKFDGKVDIDNADNIGFLIEHPKLYDNKSGLYNLKLFAQVLGKGFDKAYTDKIIDAFGMRPYIKKKVKKYSMGMKQKLAIAVSLMNKPKFLILDEPTNGMDPDGSIDVLTTIKSLVNELDMRILISSHKLEDIELICDRAVFLRDGHFVQDVNMEVGVASDTTIVTVDHKDFDRTEKYLAEHFQLQNVDKADGHLMINAQKNYQVILKALSELDIYPKYIETRKSSLRDTYFNINQRGDK
>NC_002745|1976120:2074317|2035924_2036818_-|WP_000148333.1|DBSCAN-SWA
MTGWISIDRSIQNHWLFKEKRTFSKFEAWIYLLMEANHSKAKVPIGNQIVTVERGQRLTSILTLSDLFNWSRFKVKTFLDLLESDGMLEVKTTSKYTLITIVNYDFYQSEQGRNQHQNDIKPTSKQHQSNINPTSKQHQTNTNNNDNKDNNEKNVNNEKKKTTAFDFFQDNGFGFITSYNLDDLNYYLDSFENDSDEIVTASLKIAKDRNKVTWGYAKSILNTWLNANLKSIEQVRAFEKQQLESKKQNYKPFVKQSKEKTPKWLTDSTRETKTPEVDENLEKDREAFIKRLNSKWE
>NC_002745|1976120:2074317|1991499_1991901_+|WP_000205106.1|DBSCAN-SWA
MTSYEEETDYRNVPRELLDNNIPMGRGMIKWAPFATLPEQFETIQQYIIDQNKITRPVLSDDQLAELNIRLHEALQYAQPVEVKFYNNGFVDSVRLTIYRIDAINYEIDGYVYNQQQRQKISIFDILDIVLLP
>NC_002745|1976120:2074317|2023346_2023484_-|WP_001549167.1|DBSCAN-SWA
MMDLIENGKDANEVLKMPFHYVLSIYQNKNNDISEEKAEALIDAF
>NC_002745|1976120:2074317|2009767_2010523_-|WP_000861026.1|DBSCAN-SWA
MKTYSEARARLRWYQGRYIDFDGWYGYQCADLAVDYIYWLLEIRMWGNAKDAINNDFKNMATVYENTPSFVPQIGDVAVFTKGIYKQYGHIGLVFNGGNTNQFLILEQNYDGNANTPAKLRWDNYYGCTHFIRPKYKSEGLMNKITNKINPPAQKAVGKSASKITVGSKAPYNLKWSKGAYFNAKIDGLGATSATRYGDNRTNYRFDVGQAVYAPGTLIYVFEIIDGWCRIYWNNHNEWIWHERLIVKEAF
>NC_002745|1976120:2074317|2057158_2057881_+|WP_000746599.1|DBSCAN-SWA
MKKRLLFVIVITLFIFSSNHTVLSNGDVGPGNLRNFYTKYEYVNLKNVKDKNSPESHRLEYSYKNDTLYAEFDNEYITSDLKGKNVDVFGISYKYGSNSRTIYGGVTKAENNKLDSPRIIPINLIINGKHQTVTTKSVSTDKKMVTAQEIDVKLRKYLQDEFNIYGHNDTGKGKEYGTSSKFYSGFDKGSVVFHMNDGSNFSYDLFYTGYGLPESFLKIYKDNKTVDSTQFHLDVEISKR
>NC_002745|1976120:2074317|2033325_2033571_-|WP_001282077.1|DBSCAN-SWA
MSDMLEIFLIGFGVYLFYRIAIIFLKSKKTIHTNIYEMLMLATIFMISTIAYKHQKTHILIAFLVMFFMSKLKQVQGSYEE
>NC_002745|1976120:2074317|1987355_1988285_+|WP_001140871.1|DBSCAN-SWA
MAKTYIFGHKNPDTDAISSAIIMAEFEQLRGNSGAKAYRLGDVSAETQFALDTFNVPAPELLTDDLDGQDVILVDHNEFQQSSDTIASATIKHVIDHHRIANFETAGPLCYRAEPVGCTATILYKMFRERGFEIKPEIAGLMLSAIISDSLLFKSPTCTQQDVKAAEELKDIAKVDIQKYGLDMLKAGASTTDKSVEFLLNMDAKSFTMGDYVTRIAQVNAVDLDEVLNRKEDLEKEMLAVSAQEKYDLFVLVVTDIINSDSKILVVGAEKDKVGEAFNVQLEDDMAFLSGVVSRKKQIVPQITEALTK
>NC_002745|1976120:2074317|2065677_2066058_-|WP_000356942.1|DBSCAN-SWA
MDKEQLKKYIYEYVKEYKEIPIYQLEDLFKEINHDYIGRTSITHDKDENIVFWSGWNKITMFALIELVKSEQLDLVYRGSFIMRYLLDGRVPNLPLAICYPEDGQQTDVPSWVPMVLRINKEEKIK
>NC_002745|1976120:2074317|2032332_2032749_-|WP_000590122.1|DBSCAN-SWA
MIKIEKHDIKKLEEYIQHIDNYRRELKMREYELLESHEPDNAGAGKSNLPGNPIERCAIKKFSDNRYNTLRNIVNGVDRLIDESDEDTLELLRFRYWDCPIGCYEWEDIAHYFGTSKTSILRRRNALIDKLAKYIGYV
>NC_002745|1976120:2074317|2069555_2069702_-|WP_000784885.1|DBSCAN-SWA
MKMYLTYICLVSLLTILLLAISNMYVAFSVYAWLITLGCNLTGGLENE
>NC_002745|1976120:2074317|2059636_2060197_+|WP_001035616.1|DBSCAN-SWA
MNKKLLTKTLIASALVLTTVGSGFHSSSNYNGINNVAKAEQTTDNALWKNVRDALKDANIIDKTDNENVKVTYKIENGGENTIEGTANLENISTSNNPKINPQNVTKINITRKNSNYPNIDANNTWKKLTEKLKEKNIVNNGDNVSILSTDPKDETVFGKVGEDKSNVSNRYINPKDINEIQITKK
>NC_002745|1976120:2074317|1985276_1986374_-|WP_000275727.1|DBSCAN-SWA
MYINMKDYGLTGINKTKDTRAIQRALNRGRCKPTTVYIPKGTYDICKPLTIYGNTTLLLDNETILRRCHSGPLLKNGHRFGFYRGYNGHSHIHIKGGKFDMNGVSYPYNNTAMCIGHAEDIQLIGVTIKNVVSGHAIDACGINGLYIKSCSFEGFIDYSGERFYSEAIQLDIQVPGAFPKFGTTDGTITKNVVIEDCYFGPSELPEMGSWNRAIGSHASRHNRYYENIHIRNNIFEDIQGYALTPLKYKDAFIINNKFINCEGGIRYLGVRDGKNAADVMTGKDLGSQAGINMNIIGNEFKGSMSKDAIHVRNYNNVKHKDVLIVGNTFNNSTQSIHLEDIDTVFLSPVEAGIQVTTINIDEIKK
>NC_002745|1976120:2074317|1979776_1981246_-|WP_000284436.1|DBSCAN-SWA
MYQLEDDSLMLHNDLYQINMAESYWNDNIHEKMAVFDLYFRKMPFNSGYAVFNGLKRVIDFIEHFGFSESDLEYLKSIGYKDDFLSYLKDLKFTGSIRSMQEGELCFGNEPLLRVEAPLIQAQLIETILLNIVNFHTLITTKASRIRQIASNDKLMEFGTRRAQEIDAALWGARAAYIGGFDSTSNVRAGKLFGIPVSGTHAHAFVQTYGDEYVAFKKYAERHKNCVFLVDTFHTLKSGVPNAIKVAKELGDKINFVGIRLDSGDIAYLSKEARRMLDEAGFTETKIIASNDLDEETITSLKAQGAKVDSWGVGTKLITGYDQPALGAVYKLVAIENEEGSYSDRIKLSNNAEKVTTPGKKNVYRIINKKTGKAEGDYITLENENPYDEQPLKLFHPVHTYKMKFIKSFEAIDLHHNIYENGKLVYQMPTEDESREYLAQGLQSIWDENKRFLNPQEYPVDLSKACWDNKHKRIFEVAEHVKEMEEDNE
>NC_002745|1976120:2074317|2018760_2023290_-|WP_000504568.1|tail|DBSCAN-SWA
MGERIKGLSIGLDLDAANLNRSFAEIKRNFKTLNSDLKLTGNNFKYTEKSTHSYKQRIKELDGTITGYKKNVDDLAKQYGKVSQEQGENSAEAQKLRQEYNKQANELNFLEKELEKTTTEFEEFKKAQVEAQRMAESGWGKTSKVFESMGPKLTKMGDGLKSIGKGLMIGVTAPVLGIAAASGKAFAEVDKGLDTVTQATGATGGELKKLQNSFKDVYGNFPEDAETVGGVLGEVNTRLGFTGKELESATESFLKFSHITGSDGVQAVQLITRAMGDAGIEADEYQSVLDMVAKAAQASGISVDTLADSITKYGAPMRAMGFEMKESIALFSQWEKSGVNTEIAFSGLKKAISNWGKAGKDPREEFKKTLAEIERTPDIASATSLAIEAFGAKAGPDLADAIKGGRFSYQEFLKTIEDSQGTVNQTFKDSESGSERFKVAMNKLKLVGADVWASIESAFAPVMEELIKKLSVAVDWFSSLSDGSKRSIVIFGGIAAAIGPVVFGLGAFISTVGNAVTVLAPLLASIAKAGGLISFLSTKVPILGTVFTALTGPIGIVLGVLAGLAVAFTIAYKKSETFRNFVNGAIESVKQTFSNFIQFIQPFIDSVKNIFKQAISAIVDFAKDIWSQINGFFNENGISIVQALQNICNFIKAIFEFILNFVIKPIMFAIWQVMQFIWPAVKALIVSTWENIKGVIQGAINIILGIIKVFSSLFTGNWRGVWDGIVMILKGTVQLIWNLIQLWFVGKILGVVRYFGGLLKGLITIIWVAIIGVFKKSLSAIWNATKSIFGFLFNSVKSIFTNMKNWLSSTWNNIKSNTVGKAHSLFTGVRSKFTSLWNATKDIFIKLRNWMSNIWNSIKDNTVGIAGRLWDRVRNIFGSMRDGLKSIIGKIKDHIGGMVDAVKRGLNKLIEGLNWVGGKLGMDKIPKLHTGTEHTHTTTRLVKNGKIARDTFATVGDKGRGNGPNGFRNEMIEFPNGKRVLTPNTDTTAYLPKGSKVYNGAQTYSMLNGTLPRFSIGTMWKDIKSGASSAFNWTKDQIGKGTKWLGDKVGDVLDFIENPGKLLNYILEAFGIDFNSLTKGMGIAGDITKAAWSKIKKSATDWIKENLEAMGGGDLVGGILDPDKINYHYGRTAAYTAATGRPFHEGVDFPFVYQEVRTPMGGRLTRMPFMSGGYGNYVKITSGVIDMLFAHLKNFSKSPPSGTMVKPGDVVGLTGNTGFSTGPHLHFEMRRNGRHFDPEPYLRNAKKKGRLSIGGGGATSGSGATYASRVIRQAQSILGGRYKGKWIHDQMMRVAKRESNYQSNAVNNWDINAQRGDPSRGLFQIIGSTFRANAKRGYTNFNNPVHQGISAMQYIVRRYGWDGFKRAGDYAYATGGKVFDGWYNLGEDGHPEWVIPTDPARRNDAMKMLHYAAAEVRGKNASKNKRPSQLSSVNGFDDPSLLLKMIEQQQQQIALLLKIAQSNDVIADKDYQPIIDEYAFDKKVNASIEKRERQESTKVKFRKGGIAIQ
>NC_002745|1976120:2074317|2033122_2033329_-|WP_000195784.1|DBSCAN-SWA
MTQYLVTTFKDSTGQPHEHFTTARDNQTFTVVEAESKEEAERKYEAQVKRGAVIKLGQLFENIRECGK
>NC_002745|1976120:2074317|2062500_2062842_-|WP_000358774.1|DBSCAN-SWA
MDKKQIKDFVCDYHKRTISDVLIDDEINTDEFFSIGDENSNEWMADDNIDDHIVKNHLEMIVDQVANDKEFYIFDSLIQGRSFKDISNVLECSEQSVRLWYETLLDKIVEVIE
>NC_002745|1976120:2074317|2045418_2046351_+|WP_000759682.1|DBSCAN-SWA
MKKYDIAVLDFETMNEHMNSPCEVAVSLIKDLSIVKVYSSYINPPNNRYNLKNAKIHKIPEDVILKAPKYPDIYQEILYLLKESHLIIAHNALFDISVLKNTNNYYDLPVPNFMYVDSINIFRSFHAISSFKLENLCSLYDIDKEKLHSAKFDVLALSKMLISLAKNNQHYSVLKLIHYMPKQYIRFSKYSNSPTKLFDSGFQKIHMKISEINKIEVESVIPILKDKNVVFTGNFDTEKQDLMILTRKKGAYIRSDVTAKTDILVEGVQDDKYKDVNGLVSKQRKAREYVGNGAKIQFLNEEDLINLIKE
>NC_002745|1976120:2074317|2035699_2035918_-|WP_000338528.1|DBSCAN-SWA
MDAFDKYYLFDHDGNKMFSVTPHFKDGRHLVVGIKETKFNGRRWYLDDYELNTLIDNEQMELGHQTSLFEYI
>NC_002745|1976120:2074317|1996924_1997665_-|WP_001221651.1|DBSCAN-SWA
MRILNLVKYDFYSIFKSPLTYLAILVVSSLIATQSILMANSMDNPKHIIVYGSVFAAAKWLLLIIGLMFVVKTITRDFSQGTIQLYMSKVKTRVGYIISKTISIILISILFALIHYVILIVVQASSNGKNLAFSKYVDNLWFFLIFLLFFGLFLFLITLASQKTAMIFSLGVFLVLIVPFIKPFITFIPRYGEKVLDAFDYIPFAYLTDKMISSNFDFSNWQWVISLGSIVIFFILNILYVAKKDI
>NC_002745|1976120:2074317|1978962_1979784_-|WP_000040866.1|DBSCAN-SWA
MSKLQDVIVQEMKVKKRIDSAEEIMELKQFIKNYVQSHSFIKSLVLGISGGQDSTLVGKLVQMSVNELREEGIDCTFIAVKLPYGVQKDADEVDQALRFIEPDEIVTVNIKPAVDQSVQSLKEAGIVLTDFQKGNEKARERMKVQFSIASNRQGIVVGTDHSAENITGFYTKYGDGAADIAPIFGLNKRQGRQLLAYLGAPKELYEKTPTADLEDDKPQLPDEDALGVTYEAIDNYLEGKPVTPEEQKVIENHYIRNAHKRELAYTRYTWPKS
>NC_002745|1976120:2074317|2061934_2062504_-|WP_001293088.1|terminase|DBSCAN-SWA
MSELTAKQARFVNEYIRTLNVTQSAIKAGYSANSAHVTGCRLLKKPHIKQYIQEQKDKVIDENVLTAKELLHVLTNAAVGDETETKEVVVKRGEYKENPQSGKVQLVYNEHVELVEVPIKPSDRLKARDMLGKYHKLFTDKHDINGNVPIFINIGEWDGDDEDLDKTVQEVSNANPNHTVIVDDIPLED
>NC_002745|1976120:2074317|2026574_2027720_-|WP_000154559.1|capsid|DBSCAN-SWA
MTINLSETFANAKNEFINAVNNGEPQERQNELYGDMINQLFEETKLQAKAEAERVSSLPKSAQSLSANQRSFFMDINKNVNYKEEKLLPEETIDRIFEDLTTNHPLLADLGIKNAGLRLKFLKSETSGVAVWGKIYGEIKGQLDAAFSEETAIQNKLTAFVVLPKDLNDFGPAWIERFVRVQIEEAFAVALETAFLKGTGKDQPIGLNRQVQKGVSVTEGAYPEKEEQGTLTFANPRATVNELTQVFKYHSTNEKGKSVAVKGNVTMVVNPSDAFEVQAQYTHLNANGVYVTALPFNLNVIESTVQEAGKVLTYVKGLYDGYLAGGINVQKFKETLALDDMDLYTAKQFAYGKAKDNKVAAVWKLDLKGHKPALEGTEETL
>NC_002745|1976120:2074317|2031801_2032101_-|WP_000988332.1|DBSCAN-SWA
MMTKDERIRFYKSKEWQTTRKRVLERDNYECQQCKRDGKLTTYDKSKHKSLDVDHILSLEHHPEFAHDLNNLETLCIKCHNKKEKRFIKKENKWKDEKW
>NC_002745|1976120:2074317|1995033_1995591_-|WP_001033971.1|DBSCAN-SWA
MNKITYLNELETALDALPRHLRDQKMYEYERYFYEQELNGVDEGEILKKLKDPQDVAAETKARSVIDYAESKPTFENISRAVAASLSLGILSIFVILIPVSIVGLFVLALFLISLLLLFCPIILLASAISRGIVDSISNVFFAISYSGLGLVFIIVIFKILEYIYRLILKYLLWYIKTVKGSVRK
>NC_002745|1976120:2074317|1988477_1988651_-|WP_001792184.1|DBSCAN-SWA
MIVVAVNFKWSFELYMLKVENRAMNRVHNNIYNFNHNEKGRKKTKIYTQHRKYFKKM
>NC_002745|1976120:2074317|2007560_2008010_+|WP_000727645.1|DBSCAN-SWA
MKKKLATTVLALSFLTAGISTHHHSAKAFTFEPFPTNEEIESNKKMLEKEKAYKESFKNSGLPTTLGKLDERLRNYLEKGTKNTAQFEKMVILTENKGYYTVYLNTPLAEDRKNVELLGKMYKTYFFKKGESKSSYVINGPGKTNEYAY
>NC_002745|1976120:2074317|2053167_2054391_+|WP_000206625.1|DBSCAN-SWA
MTTFSEKEKIQLLADIVELQTENNNEIDVCNYLKDLFDKYDIKSEILKVNEHRANIVAEIGNGSPILALSGHMDVVDAGNQDNWTYPPFQLTEKAGKLYGRGTTDMKGGLMALVITLIELKEQNQLPQGTIRLLATAGEEKEQEGAKLLADKGYLDDVDGLIIAEPTGSGIYYAHKGSMSCKVTATGKAVHSSVPFIGDNAIDTLLEFYNQFKEKYSELKKHDTKHELDVAPMFKSLIGKEISEEDANYASGLTAVCSIINGGKQFNSVPDEASLEFNVRPVPEYDNDFIESFFQNIINDVDSNKLSLDIPSNHRPVTSDKNSKLITTIKDVASSYVEQDEIFVSALVGATDASSFLGDNKDNVDLAIFGPGNPLMAHQIDEYIEKDMYLKYIDIFKEASIQYLKEK
>NC_002745|1976120:2074317|2025249_2025654_-|WP_000114226.1|DBSCAN-SWA
MSVKVIGDKALERELEKRFGIKEMVKVQDKALIAGAKVIVEEVKKQLKPSKDTGALINEVSFSKPEWINGKRTITVHWRGSKDRYKIVHLIEYGHVQKGTGKFIKPKAMGGVNRAIRQGQNKYFETLKRELKKL
>NC_002745|1976120:2074317|2051676_2052732_-|WP_000791411.1|DBSCAN-SWA
MKNKKRVLIASSLSCAILLLSAATTQANSAHKDSQDQNKKEHVDKSQQKDKRNVTNKDKNSTVPDDIGKNGKITKRTETVYDEKTNILQNLQFDFIDDPTYDKNVLLVKKQGSIHSNLKFESHKEEKNSNWLKYPSEYHVDFQVKRNRKTEILDQLPKNKISTAKVDSTFSYSSGGKFDSTKGIGRTSSNSYSKTISYNQQNYDTIASGKNNNWHVHWSVIANDLKYGGEVKNRNDELLFYRNTRIATVENPELSFASKYRYPALVRSGFNPEFLTYLSNEKSNEKTQFEVTYTRNQDILKNRPGIHYAPPILEKNKDGQRLIVTYEVDWKNKTVKVVDKYSDDNKPYKEG
>NC_002745|1976120:2074317|2043743_2044073_+|WP_000128909.1|DBSCAN-SWA
MTDEAKFVLLQLYSIYLGRIDEGMSKHSASYFGSDESSFNAFFLGFNFEDYIDAVLELKHRDFVIASAEDGGFLEMALSREGIAYSESESKKDYKTLMGLIRDLKKLII
>NC_002745|1976120:2074317|2069698_2070016_-|WP_000481967.1|DBSCAN-SWA
MFNINIDEDEARELLEQAINARVDELAKEKYFMTYKELSNYLNLSKPTIEELLINNGMKYYMVGSTYRFKKSDVDEFMEQLTAHMNIQNNDFKQVNIKKLLEARQ
>NC_002745|1976120:2074317|1983509_1985072_-|WP_000323161.1|DBSCAN-SWA
MAYFNQHQSMISKRYLTFFSKSKKKKPFSAGQLIGLILGPLLFLLTLLFFHPQDLPWKGVYVLAITLWIATWWITEAIPIAATSLLPIVLLPLGHILTPEQVSSEYGNDIIFLFLGGFILAIAMERWNLHTRVALTIINLIGASTSKILLGFMVATGFLSMFVSNTAAVMIMIPIGLAIIKEAHDLQEANTNQTSIQKFEKSLVLAIGYAGTIGGLGTLIGTPPLIILKGQYMQHFGHEISFAKWMIVGIPTVIVLLGITWLYLRYVAFRHDLKYLPGGQTLIKQKLDELGKMKYEEKVVQTIFVLASLLWITREFLLKKWEVTSSVADGTIAIFISILLFIIPAKNTEKHRRIIDWEVAKELPWGVLILFGGGLALAKGISESGLAKWLGEQLKSLNGVSPILIVIVITIFVLFLTEVTSNTATATMILPILATLSVAVGVHPLLLMAPAAMAANCAYMLPVGTPPNAIIFGSGKISIKQMASVGFWVNLISAIIIILVVYYVMPIVLGIDINQPLPLK
>NC_002745|1976120:2074317|2062844_2063372_-|WP_000771368.1|coat|DBSCAN-SWA
MKLLKTKNCLYYRNGDNKLSEYQLLTQFNPAFINKKIKMCEFQIESMYHMSASTTTCDEIMGVVSVSYPIEKLVIKIIETKAGLQNYKNRSINNMALLKKVLNHYTEKEQKQVVKYMRSNGRYKPYNVIERLQVDLYQASIKQRSERQKQRNTAIENSKIARVNAYHQSSYVKVV
>NC_002745|1976120:2074317|2048177_2048420_+|WP_000427213.1|DBSCAN-SWA
MENFNYNNIKKLVLENVDIDKVKEVYKDYELLNYTIKNQTLYMNDYEVAKVSEKHLNENINNLRGTVNLDEKCILSLTYL
>NC_002745|1976120:2074317|1978089_1978692_-|WP_000011542.1|DBSCAN-SWA
MSFVTENPWLMVLTIFIINVCYVTFLTMRTILTLKGYRYIAASVSFLEVLVYIVGLGLVMSNLDHIQNIIAYAFGFSIGIIVGMKIEEKLALGYTVVNVTSAEYELDLPNELRNLGYGVTHYAAFGRDGSRMVMQILTPRKYERKLMDTIKNLDPKAFIIAYEPRNIHGGFWTKGIRRRKLKDYEPEELESVVEHEIQSK
>NC_002745|1976120:2074317|2065039_2065681_-|WP_001047698.1|DBSCAN-SWA
MNLETIVNQFETRAGTLLRYYTGLLEHSKVQPCCFKLYNDPFDMVYVMMNSKLFGHVYIKDCKVRQSFELASPKHTEGLIRSIEGHYVGYELHDGKHLSISDMMASHLFEDEYFMYGLQTYAESNNSDVFEYLENGFDTDTLEGIQSSNTDVIANIEMLYQLATGINEPAPELVEGLKLVTEFVQDENATQEDYKALERKLNDLKASYYSLSK
>NC_002745|1976120:2074317|2066367_2068077_-|WP_000447473.1|DBSCAN-SWA
METGKSDVLDKIEKINKKDSALQEIIPKGYEIEHHQCGVALYQLIPSKKEGEPDKKVFITNTIPQITERFEDIESNEVSFNMLFYDNKTPVNIAVSAEEISDSRQLLKLVNKKLDVTSSTSTKLVDYINVSKRYNPPLNVKVATRLGHVKGYFIYPYQEVMKDSNVKLFSNDKGFQKLIDSFRSKGTLQGYSKKVFAQIKDLPMVMVMLYASLGSVLLREFGLQPFIVEISGSTSTGKTFTLNLVSSVWGTSDLITTWSSTQNSIESMASFLNSFPMFKDDTRNTHPKFVTSTTYNFSSGESKSRSNINLTLNAKKEWRNILISTGESSIANMADEKAGVSARVVTLQDPPYPDNFDFTTLDKSFRENYGTLGLAFIKQYESKKDVYKNAFESYQRYFNQKGSNEIMQRLGRAFALLQVTGEVLNDIDGFEHDHFKIIEQAYDSMVKNNKTIDKPKQLLEELLQYLDANRNNIVGDGYDSVNYGDVKAVYKHDFLCIKNETVKNKLGHEMQTITGQWDKKGYLIKDKKRIQKQVKHKSQRHLGYAIKKEIIEELGFDFSISHNPYTESY
>NC_002745|1976120:2074317|2070020_2070239_-|WP_000153640.1|DBSCAN-SWA
MTILANTRKFKEAMFLKGFNLSDLSRETGVGISYLSQIINGKKIPSPKLAKKMAEVLQVEVNELFEFEVKEA
>NC_002745|1976120:2074317|2070411_2071086_+|WP_000620857.1|DBSCAN-SWA
MIRNRLSELLSERGLKISRVAKDVKIARSSLTSMAQNDSEMIRYDAIDKLCSYLHISPSEFFEHNPINFDFTFDEEPNYKINDVFEGFEVTANITHAFSIENFDFEILVDVELDNRQKLNFDLDVSYKETEKITNSQHRFIFTIKNEDENIGLKKYVDSLSAGLKNLLFKKINQKLSGYVSEIIVKNIDDIEELFPNKGEKSTTLHKEILQTDSRLSSDIFKEY
>NC_002745|1976120:2074317|2044292_2044556_-|WP_000854072.1|DBSCAN-SWA
MKTLKELRTDYGLTQKELGDLFKVSSRTIQNMEKDSTNIKDSLLSKYMSAFNVKYDDIFLGNEYENFVFTNDKKKSIILAFKEKQTS
>NC_002745|1976120:2074317|2032976_2033126_-|WP_000595265.1|DBSCAN-SWA
MIKQILRLLFLLAMYELGKYVTEQVYIMMTANDDVEAPSDYVFRAEVSE
>NC_002745|1976120:2074317|2011000_2011177_-|WP_011447039.1|holin|DBSCAN-SWA
MDRWWLSEYKEVVPMVALLKSLERRRLMITISTMLQFGLFLIALIGLVIKLIELSNKK
>NC_002745|1976120:2074317|2012573_2012948_-|WP_000340977.1|DBSCAN-SWA
MDDIQKIKKELSELVERVDDVEILANETADHVLELREEHKQHHNELRESHKELKDKQDKVVDENLEQTKILNRIEERYQTQVDVAQKNEEKTLAQNKWLVGAIWALVTIVMIAVITASITALLP
>NC_002745|1976120:2074317|2035286_2035691_-|WP_000401969.1|DBSCAN-SWA
MEIEIKFNEVFNAPMGSPRPRFRNTGRFVQTYMPTSYTKHKAYIQGQMPKLNLERALKIELDFYFPLLKSWSKKKKSEMVGQYKVTKPDIDNLIKTVLDACNGHVWKDDNQITEITSSKRYGIEPKIIIRIEEI
>NC_002745|1976120:2074317|2003027_2003318_-|WP_000671712.1|DBSCAN-SWA
MKFPVTINKFENIVSNEFVFYNASKITINDLSIKLKSAMANDQGITKHDIGLAERAVYKVYFKNGSSKYVDLKTEYKDERVFKATDIKKVDIELKF
>NC_002745|1976120:2074317|2063422_2063641_-|WP_000448770.1|DBSCAN-SWA
METKYELNNTKKVANAFGLNEADTNLLINAVDLDIKNNMQEISSELQQSEQSKQKQYGTTLQNLAKQNRIIK
>NC_002745|1976120:2074317|1998533_1999214_-|WP_000645727.1|DBSCAN-SWA
MKALLIRNFKLRRYTLIIYVLLLTLYPFYIMLDSTKFFYLLQSFISPTILIIWILDAGHLFRLNRRLGGNDSYYFYMSLPVSKKQLLNANYITCIVLTLIGTLVISLYAYEADVIEPNSIYFSTAYAFVISNFLSIPIAFSQFTELRRVKVPYGIYVFTIIILVPFLFSIAIVLVNYFVLSQSSFPDLYSYILNIGFLIISIVILIVNYFKQLNKINTRKFKGGSR
>NC_002745|1976120:2074317|1988702_1990082_+|WP_001021210.1|DBSCAN-SWA
MNIIEQKFYDSKAFFNTQQTKDISFRKDQLKKLSKAIKSYESDILEALYTDLGKNKVEAYATEIGITLKSIKNARKELKNWTKTKNVDTPLYLFPTKSYIKKEPYGTVLIIAPFNYPFQLVFEPLIGAIAAGNTAIIKPSELTPNVARVIKRLINETFDANYIEVIEGGIEETQTLIHLPFDYVFFTGSENVGKIVYQAASENLVPVTLEMGGKSPVIVDETANIKVASERICFGKFTNAGQTCVAPDYILVHESVKDDLITALSKTLREFYGQNIQQSPDYGRIVNLKHYHRLTSLLNSAQMNIVFGGHSDEDERYIEPTLLDHVTSDSAIMQEEIFGPILPILTYQSLDEAIAFIHQRPKPLSLYLFSEDENATQRVINELSFGGGAINDTLMHLANPKLPFGGVGASGMGRYHGKYSFDTFTHEKSYIFKSTRLESGVHLPPYKGKFKYIKAFFKN
>NC_002745|1976120:2074317|2038938_2040882_-|WP_000700554.1|DBSCAN-SWA
MKINKLTISNFAGIKEEKFNFDGKDAKIYGNNATGKTTTATALQWLLFDKGLDGSTKSFNPVPLNEKNEENYELIPTVFAEFEIDGKITTFKKESHPKYTINQKTNRKEYSRSRTKKQYINDESIKVKDYKARIDELIDEDVFKLITNPQAFNLLDWKKRRSLLFEIAKPINDEDVIKTNDDFKELNNILGDHEIETKKKILTDKIKQINKDIKDIPIRINQTQQNKQDVPEFDNDRHTIIKQEIEQLENERIDIQNGAEEINLRNQLADKQSELKRIEANNSASNENKIHALTNELHVENGTVANLKTRLKQNKQQITHEENRRNQLLENHKGLKSDLEKAKNQKFEYLDDNVCSCCGQQLPAEQVSEVREKALQKFNANKSKELETIQTSINHIISEGKKIKPIIEKLEDDNNNLQIKINEAEERSARIQNKINKLKITHVDVTQTDEYKAVMLEINEINQKRSNIRKTIQDKVSGIDDKISELTQEKSEIEVSISIEKSNKHLDDVISELRNEEDRLLDEKEKYSHDLYILKEFTTTKVKMLTENINNEFDIAEFKLFNTLVNGELEETCSTTVNGVEYDSGLNNASRINVGLDIINTLSKHFKVTAPIFIDNAESVTELIKTESQQIQLIVNEQDKKLRMETI
>NC_002745|1976120:2074317|2041162_2041423_-|WP_000291510.1|DBSCAN-SWA
MYYKTGDVCRKIFNVDGFDFQLRVKKRAYSVEIVVLDHEGNSIDGLLVSDENDLYTALDILKQSIYEWIENNTDEQDRLINLVMKW
>NC_002745|1976120:2074317|1976120_1977287_+|WP_000827746.1|protease|DBSCAN-SWA
MKRNFPKLIALSLIFSLSVTPIANAESNSNIKAKDKKHVQVNVEDKSVPTDVRNLAQKDYLSYVTSLDKIYNKEKASYTLGEPFKIYKFNKKSDGNYYFPVLNTEGNIDYIVTISPKITKYSSSSSKYTINVSPFLSKVLNQYKDQQITILTNSKGYYVVTQNHKAKLVLKTPRLEDKKLKKTESIPTGNNVTQLKQKASVTMPTSQFKSNNYTYNEQYINKLENFKIRETQGNNGWCAGYTMSALLNATYNTNKYHAEAVMRFLHPNLQGQRFQFTGLTPREMIYFGQTQGRSPQLLNRMTTYNEVDNLTKNNKGIAVLGSRVESRNGMHAGHAMAVVGNAKLDNGQEVIIIWNPWDNGFMTQDAKNNVIPVSNGDHYRWYSSIYGY
>NC_002745|1976120:2074317|2071099_2072272_+|WP_000179343.1|integrase|DBSCAN-SWA
MASYEKRGNTWRYRISLGKDAETGKYKYISNSGFKRKSDAKHHAEMVERQLRNGDYIAPSTSTFKQVADDWISQYANEVKVSSVRAREKAIHHAIERFKNKPIQTIKKHDYQRFVNDISIQYSKNYVDSIVTSTNMIFKYAYDMKLIRILPSEGIKRPKKKVSVEELEDTEIHKKFLEKDELFQFLEIAKNHHSPQNSFEVFYTLAYTGMRAGELLALKWSDIDFENNTINITKTYYNPNNNKKQYQILTPKTESSIGKISVDPHVIKLLKNYKVDVQDTWKNELYVDNNFVFTDVNGYPLVIKKLQLWIKAILKKTNITNKQISTHSFRHTHCALLIEAGVHIKEIQERLRHKDINTTMNIYAKITNSYKKDASQKFSKLMENVSKDLF

Homologous phage analysis in the prophage region

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000827746.1|1976120_1977287_+|protease	cysteine protease staphopain A	NA	NA	NA	NA
WP_000434933.1|1977317_1977644_+	staphostatin A	NA	NA	NA	NA
WP_000669862.1|1977935_1978109_-	NETI motif-containing protein	NA	NA	NA	NA
WP_000011542.1|1978089_1978692_-	DUF2179 domain-containing protein	NA	NA	NA	NA
WP_000040866.1|1978962_1979784_-	ammonia-dependent NAD(+) synthetase	G3MA24	Bacillus_virus	2.3e-69	52.7
WP_000284436.1|1979776_1981246_-	nicotinate phosphoribosyltransferase	G3MA18	Bacillus_virus	5.9e-108	45.1
WP_000897635.1|1981429_1982506_+	nitric oxide synthase oxygenase	NA	NA	NA	NA
WP_001177828.1|1982525_1983320_+	prephenate dehydratase	NA	NA	NA	NA
WP_001802312.1|1983391_1983499_+	hypothetical protein	NA	NA	NA	NA
WP_000323161.1|1983509_1985072_-	SLC13 family permease	NA	NA	NA	NA
WP_000275727.1|1985276_1986374_-	pectate lyase	U5PWM6	Bacillus_phage	3.3e-47	34.6
WP_000149686.1|1986742_1987303_+	cysteine hydrolase	G3MA16	Bacillus_virus	2.0e-32	41.2
WP_001140871.1|1987355_1988285_+	manganese-dependent inorganic pyrophosphatase	NA	NA	NA	NA
WP_001792184.1|1988477_1988651_-	hypothetical protein	NA	NA	NA	NA
WP_001021210.1|1988702_1990082_+	aldehyde dehydrogenase	NA	NA	NA	NA
WP_000181315.1|1990201_1991230_-	lactonase family protein	NA	NA	NA	NA
WP_000205106.1|1991499_1991901_+	YolD-like family protein	U3PG23	Staphylococcus_phage	6.0e-23	42.9
WP_000267034.1|1992473_1992647_-	hypothetical protein	NA	NA	NA	NA
WP_001188043.1|1993097_1994138_+	linear amide C-N hydrolase	NA	NA	NA	NA
WP_000713072.1|1994194_1995037_-	DUF4097 family beta strand repeat protein	NA	NA	NA	NA
WP_001033971.1|1995033_1995591_-	DUF1700 domain-containing protein	NA	NA	NA	NA
WP_000966288.1|1995650_1996175_-	membrane protein	NA	NA	NA	NA
WP_000182842.1|1996295_1996859_+	thioredoxin family protein	NA	NA	NA	NA
WP_001221651.1|1996924_1997665_-	phenol-soluble modulin export ABC transporter permease subunit PmtD	NA	NA	NA	NA
WP_000763043.1|1997664_1998537_-	phenol-soluble modulin export ABC transporter ATP-binding protein PmtC	A0A2H4PQG7	Staphylococcus_phage	1.0e-27	36.0
WP_000645727.1|1998533_1999214_-	phenol-soluble modulin export ABC transporter permease subunit PmtB	NA	NA	NA	NA
WP_000991306.1|1999214_2000111_-	phenol-soluble modulin export ABC transporter ATP-binding protein PmtA	A0A2H4PQG7	Staphylococcus_phage	5.0e-17	30.2
WP_000691584.1|2000107_2000488_-	GntR family transcriptional regulator	NA	NA	NA	NA
WP_000681968.1|2000745_2000922_-	hypothetical protein	NA	NA	NA	NA
WP_000990056.1|2001164_2001263_-	hypothetical protein	NA	NA	NA	NA
WP_001068542.1|2001462_2002749_+	aminotransferase class I/II-fold pyridoxal phosphate-dependent enzyme	NA	NA	NA	NA
WP_000671712.1|2003027_2003318_-	MAP domain-containing protein	NA	NA	NA	NA
WP_001557458.1|2003332_2004763_-	MAP domain-containing protein	NA	NA	NA	NA
WP_000669789.1|2005720_2005900_+	hypothetical protein	A0A1W6JQ29	Staphylococcus_phage	2.2e-25	100.0
WP_001791826.1|2006214_2006475_+	hypothetical protein	M9NS66	Staphylococcus_phage	2.3e-23	100.0
WP_000702262.1|2006527_2006878_-	complement inhibitor SCIN-A	A7TWS0	Staphylococcus_phage	7.5e-54	100.0
WP_000727645.1|2007560_2008010_+	chemotaxis-inhibiting protein CHIPS	A0A075LZI2	Staphylococcus_phage	8.7e-79	100.0
WP_000920042.1|2009085_2009577_-	staphylokinase	A0A075LYD3	Staphylococcus_phage	8.0e-86	100.0
WP_000861026.1|2009767_2010523_-	CHAP domain-containing protein	A0A075LZV3	Staphylococcus_phage	1.2e-152	100.0
WP_000611512.1|2010534_2010789_-|holin	phage holin	D2JLG4	Staphylococcus_phage	4.1e-41	100.0
WP_031762631.1|2010840_2010948_+	hypothetical protein	NA	NA	NA	NA
WP_011447039.1|2011000_2011177_-|holin	putative holin-like toxin	D2JLG3	Staphylococcus_phage	2.2e-22	98.3
WP_025174055.1|2011379_2012153_-	staphylococcal enterotoxin type P	A0A075M4C7	Staphylococcus_phage	4.0e-148	99.6
WP_000340977.1|2012573_2012948_-	hypothetical protein	G4KNR3	Staphylococcus_phage	3.3e-39	100.0
WP_001262621.1|2013003_2013291_-	hypothetical protein	A0A1X9H0N7	Staphylococcus_phage	7.6e-44	100.0
WP_001000058.1|2013336_2013489_-	hypothetical protein	A0A1W6JPL6	Staphylococcus_phage	7.6e-19	100.0
WP_000582152.1|2013481_2017264_-	hypothetical protein	A0A068A201	Staphylococcus_phage	0.0e+00	99.6
WP_000567396.1|2017279_2018764_-|tail	phage tail family protein	A0A2I6PDJ0	Staphylococcus_phage	4.5e-297	99.8
WP_000504568.1|2018760_2023290_-|tail	phage tail tape measure protein	A0EX03	Staphylococcus_phage	0.0e+00	97.0
WP_001549167.1|2023346_2023484_-	hypothetical protein	A0A2I6PDX7	Staphylococcus_phage	3.4e-18	100.0
WP_001096355.1|2023534_2023885_-	hypothetical protein	G4KNQ8	Staphylococcus_phage	7.8e-59	100.0
WP_071621395.1|2023934_2024159_-	Ig-like domain-containing protein	A0A075LYE8	Staphylococcus_phage	3.0e-32	100.0
WP_000268740.1|2024200_2024845_-|tail	phage tail protein	G4KNQ7	Staphylococcus_phage	6.5e-120	100.0
WP_000565498.1|2024845_2025253_-	hypothetical protein	G4KNQ6	Staphylococcus_phage	7.1e-72	100.0
WP_000114226.1|2025249_2025654_-	HK97 gp10 family phage protein	G4KNQ5	Staphylococcus_phage	4.3e-69	100.0
WP_000755150.1|2025650_2026013_-|head,tail	head-tail adaptor protein	G4KNQ4	Staphylococcus_phage	4.4e-65	100.0
WP_000150936.1|2025996_2026281_-|head,tail	phage head-tail adapter protein	A0A2I6PDJ5	Staphylococcus_phage	2.3e-45	100.0
WP_000238236.1|2026270_2026555_-	hypothetical protein	A0A2I6PDJ3	Staphylococcus_phage	1.8e-45	100.0
WP_000154559.1|2026574_2027720_-|capsid	phage major capsid protein	G4KNQ3	Staphylococcus_phage	9.6e-215	100.0
WP_000642728.1|2027743_2028481_-|protease	Clp protease ClpP	G4KNQ2	Staphylococcus_phage	1.8e-129	100.0
WP_000025274.1|2028464_2029652_-|portal	phage portal protein	A0A2I6PDI1	Staphylococcus_phage	1.0e-219	100.0
WP_000625088.1|2029667_2031329_-|terminase	terminase large subunit	A0A2I6PDJ8	Staphylococcus_phage	0.0e+00	100.0
WP_000402904.1|2031325_2031670_-	hypothetical protein	G4KNP9	Staphylococcus_phage	9.4e-57	100.0
WP_000988332.1|2031801_2032101_-	HNH endonuclease	A0A2I6PDH9	Staphylococcus_phage	3.5e-52	100.0
WP_000590122.1|2032332_2032749_-	hypothetical protein	G4KNP7	Staphylococcus_phage	1.3e-76	100.0
WP_001557462.1|2032776_2032977_-	DUF1514 family protein	D2JLD9	Staphylococcus_phage	5.3e-28	98.5
WP_000595265.1|2032976_2033126_-	transcriptional activator RinB	A0A1W6JPZ2	Staphylococcus_phage	4.8e-18	100.0
WP_000195784.1|2033122_2033329_-	DUF1381 domain-containing protein	A0A2I6PEA2	Staphylococcus_phage	1.1e-17	94.1
WP_001282077.1|2033325_2033571_-	hypothetical protein	A0A2I6PDW7	Staphylococcus_phage	2.5e-35	98.8
WP_000185693.1|2033607_2034144_-	dUTP diphosphatase	Q9MBR0	Staphylococcus_prophage	1.6e-95	100.0
WP_001065108.1|2034140_2034386_-	DUF1024 family protein	Q8SDV5	Staphylococcus_phage	1.7e-36	95.1
WP_000178987.1|2034400_2034649_-	hypothetical protein	A0A0K1LL46	Staphylococcus_phage	7.5e-40	96.3
WP_000111491.1|2034645_2034903_-	DUF3310 domain-containing protein	A0A1X9H067	Staphylococcus_phage	6.3e-42	98.8
WP_000101279.1|2034902_2035274_-	hypothetical protein	A0A2I6PDG3	Staphylococcus_phage	1.4e-50	91.1
WP_000401969.1|2035286_2035691_-	RusA family crossover junction endodeoxyribonuclease	A0A075M042	Staphylococcus_phage	8.4e-73	100.0
WP_000338528.1|2035699_2035918_-	hypothetical protein	A0A1P8L6E4	Staphylococcus_phage	1.4e-37	100.0
WP_000148333.1|2035924_2036818_-	DnaD domain-containing protein	A0A1P8L6F0	Staphylococcus_phage	3.2e-141	100.0
WP_000934759.1|2036847_2037318_-	single-stranded DNA-binding protein	A0A1P8L6D9	Staphylococcus_phage	5.7e-81	100.0
WP_064135358.1|2037318_2037936_-	MBL fold metallo-hydrolase	A0A1P8L6F7	Staphylococcus_phage	1.2e-86	100.0
WP_000180600.1|2038016_2038937_-	recombinase RecT	A0A1P8L6F6	Staphylococcus_phage	5.1e-166	100.0
WP_000700554.1|2038938_2040882_-	AAA family ATPase	A0A1P8L6F1	Staphylococcus_phage	0.0e+00	100.0
WP_001205732.1|2040890_2041154_-	hypothetical protein	A0A2I6PDG2	Staphylococcus_phage	7.7e-43	100.0
WP_000291510.1|2041162_2041423_-	DUF1108 family protein	A0A1P8L6F5	Staphylococcus_phage	5.2e-44	100.0
WP_000165371.1|2041427_2041730_-	DUF2482 family protein	A0A1P8L6F8	Staphylococcus_phage	7.0e-48	100.0
WP_000048129.1|2041824_2041986_-	DUF1270 family protein	A0A1P8L6G0	Staphylococcus_phage	1.9e-20	100.0
WP_001120201.1|2041982_2042306_-	DUF771 domain-containing protein	A0A075LYF5	Staphylococcus_phage	3.0e-57	100.0
WP_000762521.1|2042360_2042741_+	DUF2513 domain-containing protein	Q9T1Z5	Staphylococcus_phage	1.2e-68	100.0
WP_001148856.1|2042727_2042925_-	hypothetical protein	O80075	Staphylococcus_phage	2.5e-30	100.0
WP_001148605.1|2042940_2043693_-	phage antirepressor KilAC domain-containing protein	M9NTH5	Staphylococcus_phage	1.1e-139	100.0
WP_000128909.1|2043743_2044073_+	hypothetical protein	M9NS98	Staphylococcus_phage	5.1e-52	98.2
WP_001025404.1|2044061_2044277_-	DUF2829 domain-containing protein	A0A0H3U4C7	Staphylococcus_phage	4.8e-35	100.0
WP_000854072.1|2044292_2044556_-	helix-turn-helix transcriptional regulator	A0A2I6PF09	Staphylococcus_phage	7.2e-41	100.0
WP_001031454.1|2044689_2045403_+	helix-turn-helix transcriptional regulator	M9NUL0	Staphylococcus_phage	1.2e-130	100.0
WP_000759682.1|2045418_2046351_+	ATP-dependent helicase	A0A2I6PEZ7	Staphylococcus_phage	5.7e-173	100.0
WP_000591749.1|2046356_2046698_+	hypothetical protein	A0A2I6PF04	Staphylococcus_phage	4.6e-56	100.0
WP_000694772.1|2046901_2047084_+	hypothetical protein	A0A2I6PDF8	Staphylococcus_phage	6.9e-27	100.0
WP_001558608.1|2047183_2048167_+	glycosyltransferase family 2 protein	NA	NA	NA	NA
WP_000427213.1|2048177_2048420_+	hypothetical protein	NA	NA	NA	NA
WP_000857180.1|2048482_2049520_+|integrase	site-specific integrase	Q38086	Staphylococcus_phage	1.4e-175	98.6
WP_000595392.1|2050638_2051655_-	bi-component leukocidin LukGH subunit G	A0A1X9IGW5	Staphylococcus_phage	6.7e-26	30.2
WP_000791411.1|2051676_2052732_-	bi-component leukocidin LukGH subunit H	A0A1X9IGW5	Staphylococcus_phage	2.8e-35	34.3
WP_000206625.1|2053167_2054391_+	ArgE/DapE family deacylase	NA	NA	NA	NA
WP_001045079.1|2054834_2056142_+	TrkH family potassium uptake protein	NA	NA	NA	NA
2056679:2056699	attL	NA	NA	NA	NA
WP_000746599.1|2057158_2057881_+	staphylococcal enterotoxin type L	A0A1X9H080	Staphylococcus_phage	2.1e-26	34.9
WP_000278088.1|2058049_2058850_-	staphylococcal enterotoxin type C3	A0A097PAT7	Streptococcus_pyogenes_phage	6.1e-51	47.5
WP_001035616.1|2059636_2060197_+	DUF4888 domain-containing protein	Q4ZBG8	Staphylococcus_virus	5.4e-62	68.1
WP_001035599.1|2061075_2061780_+	toxic shock syndrome toxin TSST-1	NA	NA	NA	NA
WP_001293088.1|2061934_2062504_-|terminase	terminase small subunit	Q4ZE85	Staphylococcus_phage	7.9e-101	97.4
WP_000358774.1|2062500_2062842_-	hypothetical protein	A0A1W6JQM3	Staphylococcus_phage	1.4e-57	99.1
WP_000771368.1|2062844_2063372_-|coat	spore coat protein	A0A1W6JQH7	Staphylococcus_phage	3.5e-87	97.1
WP_000448770.1|2063422_2063641_-	hypothetical protein	NA	NA	NA	NA
WP_000846280.1|2063658_2064237_-	hypothetical protein	A0A2H4JBG0	uncultured_Caudovirales_phage	4.8e-29	38.9
WP_001190615.1|2064248_2064590_-	hypothetical protein	Q4ZE66	Staphylococcus_phage	1.4e-57	99.1
WP_001047698.1|2065039_2065681_-	hypothetical protein	Q4ZE67	Staphylococcus_phage	7.2e-111	93.0
WP_000356942.1|2065677_2066058_-	hypothetical protein	Q4ZE71	Staphylococcus_phage	1.7e-67	96.8
WP_000447473.1|2066367_2068077_-	DUF927 domain-containing protein	Q4ZE73	Staphylococcus_phage	1.4e-302	92.8
WP_001002689.1|2068090_2068960_-	primase C-terminal domain-containing protein	Q4ZE74	Staphylococcus_phage	1.5e-164	96.2
WP_001078344.1|2069024_2069351_-	DUF1474 family protein	Q4ZE75	Staphylococcus_phage	1.5e-48	89.8
WP_001058495.1|2069353_2069563_-	hypothetical protein	Q4ZE76	Staphylococcus_phage	2.9e-29	94.2
WP_000784885.1|2069555_2069702_-	hypothetical protein	NA	NA	NA	NA
WP_000481967.1|2069698_2070016_-	helix-turn-helix domain-containing protein	A0A1W6JQE0	Staphylococcus_phage	9.2e-51	98.1
WP_000153640.1|2070020_2070239_-	helix-turn-helix transcriptional regulator	A0A2H4JB11	uncultured_Caudovirales_phage	1.3e-19	66.7
WP_000620857.1|2070411_2071086_+	helix-turn-helix transcriptional regulator	A0A2H4JGT9	uncultured_Caudovirales_phage	1.6e-39	45.8
WP_000179343.1|2071099_2072272_+|integrase	tyrosine-type recombinase/integrase	A0A1W6JQD3	Staphylococcus_phage	5.8e-215	96.2
WP_000240642.1|2072340_2073957_-	chaperonin GroEL	A0A240F779	uncultured_virus	3.4e-157	54.7
2072338:2072358	attR	NA	NA	NA	NA
WP_000917289.1|2074032_2074317_-	co-chaperone GroES	A0A221S386	uncultured_virus	4.7e-14	46.2

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage
NC_002745.2|WP_000681968.1|2000745_2000922_-|hypothetical-protein	2000745_2000922_-	58 aa aa	NA	WHTH_GntR	NA	1976120-2074317	yes
NC_002745.2|WP_000990056.1|2001164_2001263_-|hypothetical-protein	2001164_2001263_-	32 aa aa	NA	WHTH_GntR	NA	1976120-2074317	yes

Protein sequences of NC_002745.2|WP_000681968.1|2000745_2000922_-|hypothetical-protein

>NC_002745.2|WP_000681968.1|2000745_2000922_-|hypothetical-protein
MKHLTKIFVVLAIILFIIGYYLQATNHESQGIKLLLAAIMFMICAFISRSNDRRKNSK

WHTH_GntR HTH domain information

• Identity: 0.48484848484848486
• Hit_domain_coverage: 1.0

Self-targetings in the prophage

CRISPR ID	CRISPR type	Spacer info	Spacer location	Spacer length	Protospacer location	Mismatch
NC_002745_7	Orphan	7.2|1653121|22|NC_002745|PILER-CR	1653121-1653142	22	2054581-2054602	2
NC_002745_7	Orphan	7.2|1653121|22|NC_002745|PILER-CR	1653121-1653142	22	2054698-2054719	2

1. spacer 7.2|1653121|22|NC_002745|PILER-CR matches to NC_002745 position: 2054581-2054602, mismatch: 2

tgaaattggggttccaatttct	CRISPR spacer
tgaaattgggaatccaatttct	Protospacer
**********. **********

2. spacer 7.2|1653121|22|NC_002745|PILER-CR matches to NC_002745 position: 2054698-2054719, mismatch: 2

tgaaattggggttccaatttct	CRISPR spacer
tgaaattgggaatccaatttct	Protospacer
**********. **********

Protein sequences of NC_002745.2|WP_000990056.1|2001164_2001263_-|hypothetical-protein

>NC_002745.2|WP_000990056.1|2001164_2001263_-|hypothetical-protein
MMWWQEGMMTLITGGLLIIFRLWLELKWKNKK

WHTH_GntR HTH domain information

• Identity: 0.48484848484848486
• Hit_domain_coverage: 1.0

Self-targetings in the prophage

CRISPR ID	CRISPR type	Spacer info	Spacer location	Spacer length	Protospacer location	Mismatch
NC_002745_7	Orphan	7.2|1653121|22|NC_002745|PILER-CR	1653121-1653142	22	2054581-2054602	2
NC_002745_7	Orphan	7.2|1653121|22|NC_002745|PILER-CR	1653121-1653142	22	2054698-2054719	2

1. spacer 7.2|1653121|22|NC_002745|PILER-CR matches to NC_002745 position: 2054581-2054602, mismatch: 2

tgaaattggggttccaatttct	CRISPR spacer
tgaaattgggaatccaatttct	Protospacer
**********. **********

2. spacer 7.2|1653121|22|NC_002745|PILER-CR matches to NC_002745 position: 2054698-2054719, mismatch: 2

tgaaattggggttccaatttct	CRISPR spacer
tgaaattgggaatccaatttct	Protospacer
**********. **********