CRISPRimmunity

Please click to download your results

Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Target MGE spacer number	Prophage number
NC_005139	Vibrio vulnificus YJ016 chromosome I, complete sequence	1 crisprs	cas3,DinG,csa3,DEDDh,RT,WYL,csx1	0	4
NC_005128	Vibrio vulnificus YJ016 plasmid pYJ016, complete sequence	0 crisprs	NA	0	0
NC_005140	Vibrio vulnificus YJ016 chromosome II, complete sequence	2 crisprs	WYL,cas3,csa3,DEDDh,cas6,csm3gr7,csx10gr5,cas10,cas1,cas2,csx1,csx16	1	1

Results visualization

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Crispr_ID: NC_005139_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_005139_1

2293875-2293984

Orphan

Consensus_repeat	Method
GCCTCTTTGGCCGCTTTTTCCTTCGC	CRISPRCasFinder

1 spacers

The CRISPR arrays of NC_005139_1

>merge|NC_005139|1|2293875-2293984|CRISPRCasFinder
GCCTCTTTGGCCGCTTTTTCCTTCGCTATGCGCTCTTGCTCTGCCTTAGCGGCGGCTTCTTTTTCACGGCGAGCTTTTTCTTCTGCCTCTTTTGCCGCTTTTTCCTTCGC

>NC_005139|1|1|2293875-2293984|CRISPRCasFinder
GCCTCTTTGGCCGCTTTTTCCTTCGC	TATGCGCTCTTGCTCTGCCTTAGCGGCGGCTTCTTTTTCACGGCGAGCTTTTTCTTCT
GCCTCTTTTGCCGCTTTTTCCTTCGC

Protein	Signature genes	Signature genes Name	Protein_function
NC_005139.1\|WP_011080043.1\|2295645_2296065_-\|tol-pal-system-associated-acyl-CoA-thioesterase	unknown	unknown	gnl\|CDD\|274304
NC_005139.1\|WP_043877270.1\|2301537_2302998_-\|chemotaxis-protein	unknown	unknown	gnl\|CDD\|206779
NC_005139.1\|WP_011080048.1\|2291511_2292057_-\|peptidoglycan-associated-lipoprotein-Pal	unknown	unknown	gnl\|CDD\|182744
NC_005139.1\|WP_011080038.1\|2300852_2301467_-\|Holliday-junction-branch-migration-protein-RuvA	unknown	unknown	gnl\|CDD\|234645
NC_005139.1\|WP_011150785.1\|2296209_2296512_-\|cyd-operon-protein-YbgE	unknown	unknown	gnl\|CDD\|131167
NC_005139.1\|WP_011150783.1\|2292088_2293438_-\|Tol-Pal-system-protein-TolB	unknown	unknown	gnl\|CDD\|235312
NC_005139.1\|WP_011150787.1\|2299826_2300831_-\|Holliday-junction-branch-migration-DNA-helicase-RuvB	unknown	unknown	gnl\|CDD\|234619
NC_005139.1\|WP_011080044.1\|2294972_2295656_-\|protein-TolQ	unknown	unknown	gnl\|CDD\|182743
NC_005139.1\|WP_043877268.1\|2289518_2290580_-\|quinolinate-synthase-NadA	unknown	unknown	gnl\|CDD\|236489
NC_005139.1\|WP_043877267.1\|2287390_2287948_-\|DUF1190-domain-containing-protein	unknown	unknown	gnl\|CDD\|377691
NC_005139.1\|WP_011080052.1\|2287956_2288373_-\|DUF350-domain-containing-protein	unknown	unknown	gnl\|CDD\|226289
NC_005139.1\|WP_013571418.1\|2297777_2299364_-\|cytochrome-ubiquinol-oxidase-subunit-I	unknown	unknown	gnl\|CDD\|185052
NC_005139.1\|WP_011150786.1\|2296624_2297761_-\|cytochrome-d-ubiquinol-oxidase-subunit-II	unknown	unknown	gnl\|CDD\|184965
NC_005139.1\|WP_043877269.1\|2290713_2291496_-\|tol-pal-system-protein-YbgF	unknown	unknown	gnl\|CDD\|224643
NC_005139.1\|WP_011150773.1\|2282925_2285343_-\|hybrid-sensor-histidine-kinase/response-regulator	unknown	unknown	gnl\|CDD\|274362
NC_005139.1\|WP_043877266.1\|2286225_2287389_-\|glutathionylspermidine-synthase-family-protein	unknown	unknown	gnl\|CDD\|367631
NC_005139.1\|WP_011080055.1\|2285570_2286140_+\|UPF0149-family-protein	unknown	unknown	gnl\|CDD\|274071
NC_005139.1\|WP_011150779.1\|2288372_2289413_-\|potassium-channel-protein	unknown	unknown	gnl\|CDD\|369572
NC_005139.1\|WP_000270284.1\|2296504_2296612_-\|cytochrome-bd-I-oxidase-subunit-CydX	unknown	unknown	gnl\|CDD\|227227
NC_005139.1\|WP_011080045.1\|2294532_2294973_-\|ExbD/TolR-family-protein	unknown	unknown	gnl\|CDD\|274306

Protein	Function_ID	Function_description	E-value
NC_005139.1\|WP_011080043.1\|2295645_2296065_-\|tol-pal-system-associated-acyl-CoA-thioesterase	gnl\|CDD\|274304	TIGR02799, Acyl-CoA_thioesterase_YbgC, tol-pal system-associated acyl-CoA thioesterase. The tol-pal system consists of five critical genes. Inner membrane proteins TolQ and TolR convert protomotive force to energy that is transduced through TolA to an outer membrane complex of TolB and Pal. The system is known to be required to maintain outer membrane integrity. In a system with several homologous parts, ExbB and ExbD transduces energy through TonB to a variety of outer membrane proteins, many of which are siderophore receptors. The tol-pal system therefore may also be involved in transport. This family consists of a protein nearly always found in operons with the genes of the tol-pal system. The significance of this thioesterase to the tol-pal system is unclear, but either of two observations may be relevant. First, Pal, or peptidoglycan-associated lipoprotein, has a conserved N-terminal cleavage and acylation that makes it a lipoprotein. Second, the tol-pal system is implicated not only in the import of certain organics but also in the maintenance of outer membrane integrity (by an unknown mechanism).	2.03521e-66
NC_005139.1\|WP_043877270.1\|2301537_2302998_-\|chemotaxis-protein	gnl\|CDD\|206779	cd11386, MCP_signal, Methyl-accepting chemotaxis protein (MCP), signaling domain. Methyl-accepting chemotaxis proteins (MCPs or chemotaxis receptors) are an integral part of the transmembrane protein complex that controls bacterial chemotaxis, together with the histidine kinase CheA, the receptor-coupling protein CheW, receptor-modification enzymes, and localized phosphatases. MCPs contain a four helix trans membrane region, an N-terminal periplasmic ligand binding domain, and a C-terminal HAMP domain followed by a cytoplasmic signaling domain. This C-terminal signaling domain dimerizes into a four-helix bundle and interacts with CheA through the adaptor protein CheW.	6.4167e-32
NC_005139.1\|WP_011080048.1\|2291511_2292057_-\|peptidoglycan-associated-lipoprotein-Pal	gnl\|CDD\|182744	PRK10802, PRK10802, peptidoglycan-associated lipoprotein Pal.	2.82383e-68
NC_005139.1\|WP_011080038.1\|2300852_2301467_-\|Holliday-junction-branch-migration-protein-RuvA	gnl\|CDD\|234645	PRK00116, ruvA, Holliday junction branch migration protein RuvA.	1.37636e-103
NC_005139.1\|WP_011150785.1\|2296209_2296512_-\|cyd-operon-protein-YbgE	gnl\|CDD\|131167	TIGR02112, Protein_ybgE., cyd operon protein YbgE. This model describes a small protein of unknown function, about 100 amino acids in length, essentially always found in an operon with CydAB, subunits of the cytochrome d terminal oxidase. It appears to be an integral membrane protein. It is found so far only in the Proteobacteria. [Energy metabolism, Electron transport].	9.30222e-33
NC_005139.1\|WP_011150783.1\|2292088_2293438_-\|Tol-Pal-system-protein-TolB	gnl\|CDD\|235312	PRK04792, tolB, Tol-Pal system protein TolB.	0
NC_005139.1\|WP_011150787.1\|2299826_2300831_-\|Holliday-junction-branch-migration-DNA-helicase-RuvB	gnl\|CDD\|234619	PRK00080, ruvB, Holliday junction branch migration DNA helicase RuvB.	0
NC_005139.1\|WP_011080044.1\|2294972_2295656_-\|protein-TolQ	gnl\|CDD\|182743	PRK10801, PRK10801, Tol-Pal system protein TolQ.	1.24957e-120
NC_005139.1\|WP_043877268.1\|2289518_2290580_-\|quinolinate-synthase-NadA	gnl\|CDD\|236489	PRK09375, PRK09375, quinolinate synthase NadA.	0
NC_005139.1\|WP_043877267.1\|2287390_2287948_-\|DUF1190-domain-containing-protein	gnl\|CDD\|377691	pfam06693, DUF1190, Protein of unknown function (DUF1190). This family consists of several hypothetical Enterobacterial proteins of around 212 residues in length and is known as YjfM in Escherichia coli. The function of this family is unknown.	6.78979e-21
NC_005139.1\|WP_011080052.1\|2287956_2288373_-\|DUF350-domain-containing-protein	gnl\|CDD\|226289	COG3766, COG3766, Predicted membrane protein [Function unknown].	1.03443e-33
NC_005139.1\|WP_013571418.1\|2297777_2299364_-\|cytochrome-ubiquinol-oxidase-subunit-I	gnl\|CDD\|185052	PRK15097, PRK15097, cytochrome bd-I ubiquinol oxidase subunit CydA.	0
NC_005139.1\|WP_011150786.1\|2296624_2297761_-\|cytochrome-d-ubiquinol-oxidase-subunit-II	gnl\|CDD\|184965	PRK15003, PRK15003, cytochrome d ubiquinol oxidase subunit II.	4.04741e-174
NC_005139.1\|WP_043877269.1\|2290713_2291496_-\|tol-pal-system-protein-YbgF	gnl\|CDD\|224643	COG1729, COG1729, Uncharacterized protein conserved in bacteria [Function unknown].	5.94067e-49
NC_005139.1\|WP_011150773.1\|2282925_2285343_-\|hybrid-sensor-histidine-kinase/response-regulator	gnl\|CDD\|274362	TIGR02956, sensor_protein_TorS, TMAO reductase sytem sensor TorS. This protein, TorS, is part of a regulatory system for the torCAD operon that encodes the pterin molybdenum cofactor-containing enzyme trimethylamine-N-oxide (TMAO) reductase (TorA), a cognate chaperone (TorD), and a penta-haem cytochrome (TorC). TorS works together with the inducer-binding protein TorT and the response regulator TorR. TorS contains histidine kinase ATPase (pfam02518), HAMP (pfam00672), phosphoacceptor (pfam00512), and phosphotransfer (pfam01627) domains and a response regulator receiver domain (pfam00072). [Signal transduction, Two-component systems].	2.15783e-86
NC_005139.1\|WP_043877266.1\|2286225_2287389_-\|glutathionylspermidine-synthase-family-protein	gnl\|CDD\|367631	pfam03738, GSP_synth, Glutathionylspermidine synthase preATP-grasp. This region contains the Glutathionylspermidine synthase enzymatic activity EC:6.3.1.8. This is the C-terminal region in bi-enzymes. Glutathionylspermidine (GSP) synthetases of Trypanosomatidae and Escherichia coli couple hydrolysis of ATP (to ADP and Pi) with formation of an amide bond between spermidine and the glycine carboxylate of glutathione (gamma-Glu-Cys-Gly). In the pathogenic trypanosomatids, this reaction is the penultimate step in the biosynthesis of the antioxidant metabolite, trypanothione (N1,N8-bis-(glutathionyl)spermidine), and is a target for drug design. This region, the pre-ATP grasp region, probably carries the substrate-binding site.	0
NC_005139.1\|WP_011080055.1\|2285570_2286140_+\|UPF0149-family-protein	gnl\|CDD\|274071	TIGR02292, Hypothetical_protein_yecA., yecA family protein. This family resembles pfam03695 (version pfam03695.3), uncharacterised protein family UPF0149, but is broader in scope and includes additional proteins. It includes E. coli proteins YgfB and YecA. The function of this family of proteins is unknown. The crystal structure is known for the member from Haemophilus influenzae (Ygfb, HI0817). [Unknown function, General].	1.28273e-36
NC_005139.1\|WP_011150779.1\|2288372_2289413_-\|potassium-channel-protein	gnl\|CDD\|369572	pfam07885, Ion_trans_2, Ion channel. This family includes the two membrane helix type ion channels found in bacteria.	1.01726e-13
NC_005139.1\|WP_000270284.1\|2296504_2296612_-\|cytochrome-bd-I-oxidase-subunit-CydX	gnl\|CDD\|227227	COG4890, COG4890, Predicted outer membrane lipoprotein [Function unknown].	1.62085e-12
NC_005139.1\|WP_011080045.1\|2294532_2294973_-\|ExbD/TolR-family-protein	gnl\|CDD\|274306	TIGR02801, Protein_TolR, TolR protein. The model describes the inner membrane protein TolR, part of the TolR/TolQ complex that transduces energy from the proton-motive force, through TolA, to an outer membrane complex made up of TolB and Pal (peptidoglycan-associated lipoprotein). The complex is required to maintain outer membrane integrity, and defects may cause a defect in the import of some organic compounds in addition to the resulting morphologic. While several gene pairs homologous to talR and tolQ may be found in a single genome, but the scope of this model is set to favor finding only bone fide TolR, supported by operon structure as well as by score. [Transport and binding proteins, Other, Cellular processes, Pathogenesis].	3.00961e-40

>NC_005139.1|WP_011150783.1|2292088_2293438_-|Tol-Pal-system-protein-TolB
MKKRLLMGLLVLLSSVTNVANAALELIITDGIDSARPIAIVPFKWQGTKALPVDISSVVASDLQRSGKFSPVPTSKMPQTPYNESEINFDAWTNLGVDTLLTGSVTQNEKGEYVINYQLVDVVRGQLTSGQSRALEDGQLVLSKDHVLFNKVATITAPRMREYAHRISDLIYEQLTGERGAFLTRIAYVVVNDKDKFPYQLRVADYDGFNERLVLRSKQPLMSPAWSPDGRQLAYVSFQNGQAEIFVLNIYTGEHEKLTSFPRHNGAPRFSPDGKKLAIVLSKTGSLQIYTLDLQTRQLTQITRDRSNNTEPFWHPDGKSLIFTSDRGGKPQIYRVNLSDGSTSRLTWQGSQNLGGQITPDGRFLIMVNRSDSGFNLAKQDLETGAVQVLTKTLLDESPSIAPNGGMVIYSSIYDKKNVLSMVSIDGRFKARLPATNGRVRAPAWSPFL
>NC_005139.1|WP_011080048.1|2291511_2292057_-|peptidoglycan-associated-lipoprotein-Pal
MQLNKVLKGLLIALPVMAVTACSSSDDAASNAGTSTETNQTTSGSANTTDTTVVTPIDQNGQLSEQELKEQALRETQTIYFAFDNATISSDYEEMLAAHAAYLSKNVNLKVTIEGHADERGTPEYNIALGERRAQAVAKYLQALGVQADQIAIVSYGEEKPLLLGQTEEVYAKNRRAVLVY
>NC_005139.1|WP_043877269.1|2290713_2291496_-|tol-pal-system-protein-YbgF
MFSNTKRAVTLTLLASAANLAFAAPAPVSDLNSDSTNTSVASATSSSAPETDVQRLERLLQNRNRVQLQMQQQIDQMSQEIAELRGQLERNSYDMQQMLERQRELFIELDRVRNEIKTVGTPTQATAVEEGGEQGVFSSNVDEQTAYQNAVDLILKKRDYAGAIAAFKQFQIDFPDSNFAPNSHYWLGQLYFAQKQDKEAAKSFAAVVSYKDSNKRADALVKLGDIAARNNNPEQAKKYYQQAIDEHPGSASAKVAKSKL
>NC_005139.1|WP_043877268.1|2289518_2290580_-|quinolinate-synthase-NadA
MSHILDKIDTVYPFPPKPIPLTQDEKAAYIASIKQLLKEKDAVLIAHYYTDPEIQALAEETGGFVGDSLEMAKFGNRHPAGTLIIAGVRFMGESAKILTPEKRILMPTLEAECSLDLGCPADKFTEFCDAHPDHTVVVYANTSAAVKARADWVVTSSIALEIVEHLDAEDKPIIWGPDRHLGSYIANKTGADMLLWQGECVVHDEFSADALRKMKAVYPDAAILVHPESPASVVELADAVGSTSQLIKAAKELPQQKMIVATDKGIFFKMQQLVPEKELIEAPTAGAGATCRSCAHCPWMAMNGLKAIETALREGGEQHEIFVDEALRVKSLIPLNRMLDFAEKLNMQVKGNV
>NC_005139.1|WP_011150779.1|2288372_2289413_-|potassium-channel-protein
MSVWFLLKKWFQAHVFSLSNRNLFILLVCYVALCWLLLTWAGEQALTENVTTFVYYLMVTASTVGYGDLSPATPLGRWVVILVVIPGGLSLFAALLGRVASSVIDYWRAGVLGKRRVRVNNHILLLGWNGQRTVHLIRMLQHEEVGKRPIVLCSRSDIENPLPGEIGFVKVTSYTDALEMANANVADASCIIVDNQQDDITLSAALYCANINPNAHLLAYFKDDALGQLLSQHCPKAECIPAVGAEMLAKAAVDPGSSALHQELLASTRGMTQYSVEYPKHLAQTNVDALFSFLKKHHQATLIAVDVGQGIELNPHLDRKVPSGAKLFYIADERIHSFEWEAIKEN
>NC_005139.1|WP_011080052.1|2287956_2288373_-|DUF350-domain-containing-protein
MSVLSGLLAGFTNFLLYFSLSIAFVLAFKFIYVRLTPYDEWKLIKEHSNTAAAIALSGAFLGYCIAISGAAKNAISLVDFAVWGVVAMCAQVIAFAIVRFVLVPRITERIERDEIPAGIISATVSISVGVLNAACMSY
>NC_005139.1|WP_043877267.1|2287390_2287948_-|DUF1190-domain-containing-protein
MKRSSNVKKSSFEKIMPAIPYVLFGGFFAYTVYEPETEGYIFKDADHCKRNNPEFGAQCDLAYQEALARAEYSAPKYSSSQACRSEFSDDECHYSSVYHSYIPRMNSFFYTADTSGLKNSSKSFFSEPLYRYKHGYYSGSGVSYGSTLGKAVNINTSSLKSSGGTIGKVMSRGGFGRSVSVSRGG
>NC_005139.1|WP_043877266.1|2286225_2287389_-|glutathionylspermidine-synthase-family-protein
MFRREIEERAHWRALAKRYGFGFHTMYGQPYWDESAYYQFNLQQIEQDLEAPTEEIHQMCLSIVDKVVHNEQLLARFGIPQPMWEQVRLSWMMNEPSLYSRLDFAYAGNGPAKLYENNADTPTSLFETAFWQWLWLEDVVNQGSVSRRADQFNILQDFLIERFRQIARFQPGQTLHFSCCKETEEDRATVQYLEDCAKEAGLQTAFVFIEDIGIDSRSCFVDAENRVIRWMFKLYPWEEMFSDEYSRFLSEAKVNWLEPMWKSVLSNKALLPLLWQEFEGHPNLLPAYFSDDPKASSLKDFVIKPLFSREGANIEIVRNGKTHHKTEGPYGEGRFIVQQYCPLPKFGNSHTLIGSWLVNDKAAGISIREDSSIITQDLARYLPHVIL
>NC_005139.1|WP_011080055.1|2285570_2286140_+|UPF0149-family-protein
MNLHNIIALPELEGKLLNHAKTQGFVTSMAAAPNILPPNEWLPFLWGGEETAPFLDGEQLESYIDAIVNLWNQARPALIEGTWQWPEECALDEAEIVNEATRDFCEGLLQGWQLARDDWETLMPEHSEENALLGGVLLSLTMLYDPETTIATLSEQGFDGLDQFAEIFNAMPMMLCGLTQRGVMLADEQ
>NC_005139.1|WP_011150773.1|2282925_2285343_-|hybrid-sensor-histidine-kinase/response-regulator
MRIRSSLRKKSIYALSLYLCFFIATIGSVAYLVVEPPVRSNIERNLDLRTELLASQIKSPFNRAVGVLNSLVGVAQSQQKGENQPQILGKIIASSDQVIASGGVWPEPQQIDGSLRYVSLFFNKGEDGRIEQIHSYNNPESSGYHTESWYLSVVNLPENSVAWSNVYTDPYTQVQMITASQPYFIDGEFAGVATVDISLETLFDFVKGHTEKYQLGVSISDPGGKLLLEHAFHLTRDRYISEIEVADIGWRVRVINSQLTVSDEVFGQVMRVEAGILPFLLICVLVGYYTLNRYVIKPIISIAKKVDVSKTGGIIDIHYDSEDEIKHLIETINEKTVYLEAEKVKAQASTNAKTAFLATLSHEIRTPMNGVLGTAQILLKTPLNEEQRKHLKTLYDSGDHMMTLLNEILDYSKIEQGHMEFDNNPFPFDSIIGSVNSVYYTLCAEKGLQFKVYSTVPTGRWYCADKARLRQVLFNLLNNAVKFTARGLVEVYFEEHTREQANYLSIKVKDTGIGIPESAQKRIFRPFEQAESSTTRRFGGTGLGLAIVKQIAEQMGGSVAVSSQVGLGTCFTVELALECTSPETESPEPRYKLNYQGLRALIVEDNRTNAIIIETFLRNKGFSCERVENGEQAIACVTQHPFDLILMDNHMPVMDGIEAITAIRAMDSPCRHTLIFGCTADVFKETRERMLGVGADHIIAKPIVEAELDDALFQHAKLLYQFRAEDVQAQIEEQSIESLLVGFYIAIENGELTQAHNAISQIRGQHKDAIEPALAQSLARIEQQLSENKQPDQEEINLLTVLLAD
>NC_005139.1|WP_011080045.1|2294532_2294973_-|ExbD/TolR-family-protein
MAGYQPKKRKMTAEINVVPYIDVMLVLLIIFMATAPFVSQGVDVELPKTSNAKTMSDLAGESDSSFIIIEVDSEGNLGLSVNNDEVQRGLSLEDVIVRVKAELSLKPNSPVAVGGDAATPYAEVVLLLDELSKAGIEKVGLLTDIK
>NC_005139.1|WP_011080044.1|2294972_2295656_-|protein-TolQ
MTADISILDLFLQASLLVKLVMLTLLGMSVVSWAMIIKRSKVLSKAAKDAEEFEDKFWSGIDLSQLYQQIKARKDELSGTEEIFYAGFTEFARLRKTNPTSPDFVMEGTGRAMRVAVSREVDELETSLPFLATVGSITPYIGLFGTVWGIMHAFIALGEVKQATLSMVAPGIAEALIATAMGLFAAIPAVMAYNRFASKVGKLEHNYSTFSEEFHSILHRQAMAGSQ
>NC_005139.1|WP_011080043.1|2295645_2296065_-|tol-pal-system-associated-acyl-CoA-thioesterase
MNGIRQPFTWPVTVYYEDTDAGGVVYHSNYLKFFERARTELLRSVGISQNVLLEQNIGFVVRHMDIDFIQGARLDQHLTILTKIGEIKRASLLFCQELVNDDGKLLCKATVKVACIDNVKMKPIAIPTSIISELTNSDC
>NC_005139.1|WP_011150785.1|2296209_2296512_-|cyd-operon-protein-YbgE
MSNLDARIASLHDPLDKTILKVIALLLGFLHVGLVMWDPEAYATAIGGFNALIGPALIWAVCSSMVYGVGFKPRKWVWQLLFSPYFSLSILLFLTALYIL
>NC_005139.1|WP_000270284.1|2296504_2296612_-|cytochrome-bd-I-oxidase-subunit-CydX
MWYFAWILGVLLACAFGIINALWLEHSEMMDKDSE
>NC_005139.1|WP_011150786.1|2296624_2297761_-|cytochrome-d-ubiquinol-oxidase-subunit-II
MFDYEILRLIWWVLIGVLLVGFAVTDGFDMGVGALVPVIGKNDTERRVMINTIAPHWDGNQVWLITAGGALFAAWPLVYATSFSGFYLAMYVTLAALWLRPLGLDYRSKIENPKWRNAWDGAICFSGAVPPVIFGVAFGNLLQGVPFELNNLLMSEYKGSFFALLNPFALLCGVLSLMLFVLQGATWLQMKTTEALHTRARNVAQIAGLVVVALFVIGGFWVQSIEGYVITSTIDTFADSNPLNKEVVQQAGAWMANFETYPAMWAAPVLGVFMPLLAVIASRFERGGFAFLFSSLANAGVILTAGFAMFPFVMPSSLVPAHSLTMWDSTASELTLGLMTAVAAVMVPVILGYTTWTYYKMFGRLDKKHIEDNDVSAY
>NC_005139.1|WP_013571418.1|2297777_2299364_-|cytochrome-ubiquinol-oxidase-subunit-I
MIDVVDLSRLQFALTAMYHFLFVPLTLGMAFLLAIMESLYVMTDKQIYKDMTKFWGKLFGINFALGVATGLTMEFQFGTNWSYYSHYVGDIFGAPLAIEALVAFFLESTFVGLFFFGWERLSKRQHLAVTWLVALGSNFSALWILVANGWMQNPVGAEFNFETMRMEMVSFAEVVLNPVAQVKFVHTVASGYTTGAMFILGISSYYLLKGRDVAFARRSFAIAASFGMASILSVIVLGDESGYELGEVQKVKLAAVEAEWHTEPAPAAFTLFGLPNQETMHTDYAIKIPYVMGIIATRSFDEQVTGLRDLRDQHVDRIRNGMYAYELLEKLRAGDRSEANKAAFDEVKGDLGYGLLLKRYTDKVTDATEEQIQAAADDSIPTVWPLFMSFRIMVGCGFIMLFVFGAAFVQTCRQKIEQKPWILKAALFSIPLPWIAIEAGWFVAEYGRQPWAVGEILPTHVAASALTIGELWTSLFAILALYTVFLIAEVYLMLKFARKGPSSLKTGRYHFEQNGESIEDKVNRQVEA
>NC_005139.1|WP_011150787.1|2299826_2300831_-|Holliday-junction-branch-migration-DNA-helicase-RuvB
MIEADRLIAPENPAFRDEDVIDRAIRPKKLADYQGQDHVRDQMEIFIKAAQLRNEALDHLLIFGPPGLGKTTLANIVANEMGVNIRTTSGPVLEKAGDLAALLTNLEENDVLFIDEIHRLSPMVEEVLYPAMEDYQLDIMIGEGPAARSIKIDLPPFTLIGATTRAGSLTSPLRDRFGITQRLEYYKIPDLQNIVQRSADCLGLSMEAEGALEVARRARGTPRIANRLLRRVRDFAEVKGNGHICADTADKALNMLDVDSKGFDYMDRKLLLAIMEKFGGGPVGLDNMAAAIGEEKDTIEDVLEPYLIQQGYLQRTPRGRIATDRAYLHFGIEK
>NC_005139.1|WP_011080038.1|2300852_2301467_-|Holliday-junction-branch-migration-protein-RuvA
MIGRLRGILLEKQPPELLIEVNGIGYEVQMPMSCFYELPNIGEEAIIYTHFVVREDAQLLYGFNTVKERALFREVIKANGVGPKLGLAILSGMTASQFVASVEREDISTLVKLPGVGKKTAERLVVEMKDRLKGWSAGDLFTPFTDAAPVDSGSTSSNSAEEEAVSALLALGYKPVQASKVVSQIAKPDMTSEQLIREALKSMV
>NC_005139.1|WP_043877270.1|2301537_2302998_-|chemotaxis-protein
MNPAHLWHRFCVPSQAQWTSAQQRQAAILSLFTFIAFLVGLYSLFKWSRHGHESLITTSIALILCELAAAAVLRWSRQPILALNIGFVGMVTHALNIIYQSGGVVESTQTYWVPLLIVAFFLSATRIMALIWSGSVIMIAALMTYFHLSGVAFPQLELASSALRVEIWSGTVLPLVVICIAQAYTAGQRDKAISGAERATAQSEEAALNAKQGAANLTQVLQQATVSSTELNQVSLALDSQSQTLDAQVSQLNLNCQSQASAAEEISQQIHHIAEGLNESGRFVSELQQRSETVHQQAAESSRLLVDSTQAITQILTSHEQIMRVADLITSVAEQTNLLALNAAIEAARAGEQGRGFAVVAEQVRELSSKSSYSALEIRQLLDRSEQEVRHGQQVVHLSAERMENIIAQINTIHVDVQALADIVRQQNQAVKELDDASSEVALNVANTKCVADVVADNGSELRQHVNKVRLLSNQLDQVISKNATH

You can click texts colored in the table to view more detailed information

Click the colored protein region to show detailed information

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

540195 : 548284

Vibrio_phage(33.33%)

tRNA,transposase,integrase

attL 530736:530750|attR 550864:550878

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
530736:530750	attL	NA	NA	NA	NA
WP_167524320.1\|540195_540892_+\|transposase	IS1 family transposase	A0A0U2RK18	Escherichia_phage	9.1e-67	51.7
WP_011149473.1\|540908_542138_-\|integrase	tyrosine-type recombinase/integrase	A0A1V0E8G8	Vibrio_phage	5.3e-110	47.9
WP_011078714.1\|542524_544399_-	RNA polymerase sigma factor RpoD	A0A2I7SAT0	Vibrio_phage	3.2e-34	32.2
WP_026130526.1\|544498_546262_-	DNA primase	A0A1S5RFR1	Helicobacter_phage	1.5e-44	29.0
WP_011078712.1\|546348_546792_-	GatB/YqeY domain-containing protein	A0A292GL36	Xanthomonas_phage	2.9e-26	46.6
WP_001145625.1\|546820_547036_-	30S ribosomal protein S21	NA	NA	NA	NA
WP_011078711.1\|547264_548284_+\|tRNA	tRNA (adenosine(37)-N6)-threonylcarbamoyltransferase complex transferase subunit TsaD	A0A0R6PI74	Moraxella_phage	4.8e-109	58.9
550864:550878	attR	NA	NA	NA	NA

DBSCAN-SWA_2

760665 : 767720

Faustovirus(16.67%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_011149600.1\|760665_761880_+	IscS subfamily cysteine desulfurase	A0A0H3TPH2	Faustovirus	2.2e-31	31.6
WP_011078536.1\|761923_762307_+	Fe-S cluster assembly scaffold IscU	A0A218MKD1	uncultured_virus	2.0e-52	77.4
WP_011149601.1\|762379_762703_+	iron-sulfur cluster assembly protein IscA	A0A2H4N7N5	Lake_Baikal_phage	1.8e-25	52.3
WP_011149602.1\|762763_763279_+	co-chaperone HscB	NA	NA	NA	NA
WP_011149603.1\|763300_765154_+	Fe-S protein assembly chaperone HscA	A0A0N9QXN8	Chrysochromulina_ericina_virus	6.3e-107	39.0
WP_011078532.1\|765165_765504_+	ISC system 2Fe-2S type ferredoxin	NA	NA	NA	NA
WP_011078531.1\|765585_765780_+	Fe-S cluster assembly protein IscX	NA	NA	NA	NA
WP_011078530.1\|765932_767231_+	aminopeptidase PepB	Q6GYZ8	Mycoplasma_phage	6.5e-34	32.8
WP_011078529.1\|767294_767720_+	nucleoside-diphosphate kinase	A0A167REB2	Powai_lake_megavirus	5.1e-20	41.4

DBSCAN-SWA_3

863122 : 869830

Staphylococcus_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_011149676.1\|863122_864262_+	glutamate 5-kinase	A0A1X9I5D0	Streptococcus_phage	1.6e-65	40.7
WP_080505638.1\|864274_865543_+	glutamate-5-semialdehyde dehydrogenase	A0A1X9I5D4	Streptococcus_phage	1.8e-100	49.2
WP_011149678.1\|865743_866193_+	transcriptional regulator NrdR	NA	NA	NA	NA
WP_011149679.1\|866212_867319_+	bifunctional diaminohydroxyphosphoribosylaminopyrimidine deaminase/5-amino-6-(5-phosphoribosylamino)uracil reductase RibD	A0A1V0SE20	Indivirus	5.5e-42	33.3
WP_011078426.1\|867320_867977_+	riboflavin synthase	A0A2H4PQS5	Staphylococcus_phage	1.2e-33	35.9
WP_043877087.1\|868074_869184_+	bifunctional 3,4-dihydroxy-2-butanone-4-phosphate synthase/GTP cyclohydrolase II	A0A2H4PQS2	Staphylococcus_phage	3.0e-64	40.4
WP_011078424.1\|869359_869830_+	6,7-dimethyl-8-ribityllumazine synthase	A0A2H4PQS3	Staphylococcus_phage	2.2e-32	48.7

DBSCAN-SWA_4

2860181 : 2875429

uncultured_Mediterranean_phage(22.22%)

tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_011151142.1\|2860181_2862764_-\|tRNA	alanine--tRNA ligase	A0A1V0SK38	Klosneuvirus	2.9e-78	37.9
WP_011151143.1\|2862943_2863405_-	recombination regulator RecX	NA	NA	NA	NA
WP_011079524.1\|2863508_2864558_-	recombinase RecA	A0A2D1GPX2	Mycobacterium_phage	1.4e-111	60.1
WP_011151145.1\|2864691_2865195_-	nicotinamide-nucleotide amidase	B5TK85	Pseudomonas_phage	1.4e-24	43.9
WP_043877315.1\|2865278_2867840_+	DNA mismatch repair protein MutS	A0A1V0SC35	Catovirus	1.0e-30	22.2
WP_011151147.1\|2867915_2868908_-	RNA polymerase sigma factor RpoS	F4YCU2	Synechococcus_phage	1.5e-35	34.8
WP_039554645.1\|2868988_2869885_-	peptidoglycan DD-metalloendopeptidase family protein	I3PV79	Clostridium_phage	1.5e-13	34.1
WP_011079519.1\|2869928_2870555_-	protein-L-isoaspartate(D-aspartate) O-methyltransferase	A0A1B1IU40	uncultured_Mediterranean_phage	2.1e-38	53.6
WP_011151150.1\|2870557_2871325_-	5'/3'-nucleotidase SurE	A0A1B1ITZ2	uncultured_Mediterranean_phage	6.9e-68	51.0
WP_026130623.1\|2871330_2872374_-\|tRNA	tRNA pseudouridine(13) synthase TruD	NA	NA	NA	NA
WP_011151152.1\|2872415_2872892_-	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase	NA	NA	NA	NA
WP_011151153.1\|2872888_2873602_-	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase	NA	NA	NA	NA
WP_011079514.1\|2873601_2873883_-	cell division protein FtsB	NA	NA	NA	NA
WP_013571121.1\|2874127_2875429_-	phosphopyruvate hydratase	A0A1X9I5Z8	Streptococcus_phage	4.7e-133	58.9

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

2. NC_005140

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Crispr_ID: NC_005140_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_005140_1

1691478-1691653

TypeIII

Consensus_repeat	Method
GTTTCAGACATGCCCGGTTTAGACGGGATTAAGAC	CRISPRCasFinder

2 spacers

cas10,csm3gr7,csx10gr5,cas6,cas1,cas2,csx1,csx16

The CRISPR arrays of NC_005140_1

>merge|NC_005140|1|1691478-1691653|CRISPRCasFinder
GTTTCAGACATGCCCGGTTTAGACGGGATTAAGACCTAATACACCGCACCACTTCTTAAACTATCAACAAAGGTTTCAGACATGCCCGGTTTAGACGGGATTAAGACACTGCAAGAGTCACCAATAGTTTTATAGGTTTCGGTTTCAGACATGCCCGGTTTAGACGGGATAACGAA

>NC_005140|1|1|1691478-1691653|CRISPRCasFinder
GTTTCAGACATGCCCGGTTTAGACGGGATTAAGAC	CTAATACACCGCACCACTTCTTAAACTATCAACAAAG
GTTTCAGACATGCCCGGTTTAGACGGGATTAAGAC	ACTGCAAGAGTCACCAATAGTTTTATAGGTTTCG
GTTTCAGACATGCCCGGTTTAGACGGGATAACGAA

Protein	Signature genes	Signature genes Name	Protein_function
NC_005140.1\|WP_011152745.1\|1685901_1687479_-\|hypothetical-protein	csx10gr5	cls000748_csx10gr5_CAS-III-D	gnl\|CDD\|131722
NC_005140.1\|WP_043877604.1\|1688074_1689850_-\|hypothetical-protein	cas10	cls000686_cas10_CAS-III	unknown
NC_005140.1\|WP_011152748.1\|1690470_1691262_+\|hypothetical-protein	unknown	unknown	unknown
NC_005140.1\|WP_011152746.1\|1687475_1688078_-\|hypothetical-protein	csm3gr7	cd09726_csm3gr7_CAS-III-D	gnl\|CDD\|187857
NC_005140.1\|WP_011152758.1\|1702365_1702512_+\|hypothetical-protein	unknown	unknown	unknown
NC_005140.1\|WP_043877606.1\|1696969_1697260_+\|CRISPR-associated-protein-Csx16	csx16	pfam09652_csx16_CAS-I:CAS-III	gnl\|CDD\|200203
NC_005140.1\|WP_011152756.1\|1698532_1699708_+\|TIGR02221-family-CRISPR-associated-protein	csx1	cd09668_csx1_CAS-III	gnl\|CDD\|274040
NC_005140.1\|WP_043877607.1\|1697290_1698520_+\|CRISPR-associated-protein-Csx16	csx16	pfam09652_csx16_CAS-I:CAS-III	gnl\|CDD\|200203
NC_005140.1\|WP_011152743.1\|1683965_1684481_-\|hypothetical-protein	unknown	unknown	unknown
NC_005140.1\|WP_011081941.1\|1679757_1680213_+\|peptide-methionine-(R)-S-oxide-reductase-MsrB	unknown	unknown	gnl\|CDD\|376583
NC_005140.1\|WP_011152752.1\|1694068_1694347_+\|CRISPR-associated-endonuclease-Cas2	cas2	cd09725_cas2_CAS-I:CAS-II:CAS-III:CAS-V	gnl\|CDD\|187856
NC_005140.1\|WP_011152741.1\|1680901_1681792_-\|CRISPR-system-precrRNA-processing-endoribonuclease-RAMP-protein-Cas6	cas6	mkCas0066_cas6_CAS-I:CAS-III	gnl\|CDD\|337605
NC_005140.1\|WP_011152740.1\|1680209_1680737_+\|peptide-methionine-(S)-S-oxide-reductase-MsrA	unknown	unknown	gnl\|CDD\|376578
NC_005140.1\|WP_011152757.1\|1699933_1702207_+\|hypothetical-protein	unknown	unknown	unknown
NC_005140.1\|WP_011152744.1\|1684477_1685905_-\|hypothetical-protein	csm3gr7	cd09726_csm3gr7_CAS-III-D	gnl\|CDD\|377130
NC_005140.1\|WP_011081943.1\|1702517_1702766_+\|DUF3297-family-protein	unknown	unknown	gnl\|CDD\|371696
NC_005140.1\|WP_043877603.1\|1681788_1683951_-\|TIGR03986-family-CRISPR-associated-RAMP-protein	csm3gr7	cls000253_csm3gr7_CAS-III-A:CAS-III-D	gnl\|CDD\|274902
NC_005140.1\|WP_043877605.1\|1693775_1694060_+\|CRISPR-associated-endonuclease-Cas2	cas2	cd09725_cas2_CAS-I:CAS-II:CAS-III:CAS-V	gnl\|CDD\|187856
NC_005140.1\|WP_052281496.1\|1695360_1696662_-\|TIGR02584-family-CRISPR-associated-protein	csx1	cd09686_csx1_CAS-III	gnl\|CDD\|187817
NC_005140.1\|WP_011152750.1\|1691703_1693776_+\|CRISPR-associated-endonuclease-Cas1	cas1	cd09634_cas1_CAS-I:CAS-II:CAS-III:CAS-V	gnl\|CDD\|187766

Protein	Cas_name	Cas_description	E-value	Identity	Coverage
NC_005140.1\|WP_011152745.1\|1685901_1687479_-\|hypothetical-protein	csx10gr5	cls000748_csx10gr5_CAS-III-D	2.5e-36	119.8	0.0
NC_005140.1\|WP_043877604.1\|1688074_1689850_-\|hypothetical-protein	cas10	cls000686_cas10_CAS-III	0	1427.8	4.7
NC_005140.1\|WP_011152750.1\|1691703_1693776_+\|CRISPR-associated-endonuclease-Cas1	cas1	cd09634_cas1_CAS-I:CAS-II:CAS-III:CAS-V	6.7e-94	309.2	0.0
NC_005140.1\|WP_011152752.1\|1694068_1694347_+\|CRISPR-associated-endonuclease-Cas2	cas2	cd09725_cas2_CAS-I:CAS-II:CAS-III:CAS-V	6.8e-24	78.7	0.1
NC_005140.1\|WP_043877606.1\|1696969_1697260_+\|CRISPR-associated-protein-Csx16	csx16	pfam09652_csx16_CAS-I:CAS-III	5.6e-44	143.1	0.0
NC_005140.1\|WP_011152756.1\|1698532_1699708_+\|TIGR02221-family-CRISPR-associated-protein	csx1	cd09668_csx1_CAS-III	2.3e-87	287.2	0.0
NC_005140.1\|WP_011152744.1\|1684477_1685905_-\|hypothetical-protein	csm3gr7	cd09726_csm3gr7_CAS-III-D	4.4e-28	93.6	0.0
NC_005140.1\|WP_043877607.1\|1697290_1698520_+\|CRISPR-associated-protein-Csx16	csx16	pfam09652_csx16_CAS-I:CAS-III	1.9e-38	125.4	0.7
NC_005140.1\|WP_011152741.1\|1680901_1681792_-\|CRISPR-system-precrRNA-processing-endoribonuclease-RAMP-protein-Cas6	cas6	mkCas0066_cas6_CAS-I:CAS-III	2.7e-62	205.6	0.1
NC_005140.1\|WP_011152746.1\|1687475_1688078_-\|hypothetical-protein	csm3gr7	cd09726_csm3gr7_CAS-III-D	5.2e-19	64.1	0.0
NC_005140.1\|WP_043877603.1\|1681788_1683951_-\|TIGR03986-family-CRISPR-associated-RAMP-protein	csm3gr7	cls000253_csm3gr7_CAS-III-A:CAS-III-D	4.1e-196	648.4	0.1
NC_005140.1\|WP_052281496.1\|1695360_1696662_-\|TIGR02584-family-CRISPR-associated-protein	csx1	cd09686_csx1_CAS-III	2.1e-100	329.6	0.0
NC_005140.1\|WP_043877605.1\|1693775_1694060_+\|CRISPR-associated-endonuclease-Cas2	cas2	cd09725_cas2_CAS-I:CAS-II:CAS-III:CAS-V	7.6e-24	78.5	0.2

Protein	Function_ID	Function_description	E-value
NC_005140.1\|WP_011152741.1\|1680901_1681792_-\|CRISPR-system-precrRNA-processing-endoribonuclease-RAMP-protein-Cas6	gnl\|CDD\|337605	pfam10040, CRISPR_Cas6, CRISPR-associated endoribonuclease Cas6. Cas6 is a member of the RAMP (repeat-associated mysterious protein) superfamily. It is among the most widely distributed Cas proteins and is found in both bacteria and archaea. Cas6 functions in the generation of CRISPR-derived guide RNAs for invader defense in prokaryotes.	6.86665e-06
NC_005140.1\|WP_011152752.1\|1694068_1694347_+\|CRISPR-associated-endonuclease-Cas2	gnl\|CDD\|187856	cd09725, Cas2_I_II_III, CRISPR/Cas system-associated protein Cas2. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas2 is present in majority of CRISPR/Cas systems along with Cas1; RNAse specific to U-rich regions; Possesses an RRM/ferredoxin fold.	1.30813e-22
NC_005140.1\|WP_043877606.1\|1696969_1697260_+\|CRISPR-associated-protein-Csx16	gnl\|CDD\|200203	TIGR02620, hypothetical_protein, putative CRISPR-associated protein, VVA1548 family. This model represents a conserved domain of about 95 amino acids exclusively in species with CRISPR (Clustered Regularly Interspaced Short Palidromic Repeats). In all bacterial species with members so far (Vibrio vulnificus YJ016, Mannheimia succiniciproducens MBEL55E, and Nitrosomonas europaea ATCC 19718) and but not in the archaeon Methanothermobacter thermautotrophicus str. Delta H, the gene for this protein is in the midst of a cluster of Cas protein gene near CRISPR repeats.	5.79554e-53
NC_005140.1\|WP_011152756.1\|1698532_1699708_+\|TIGR02221-family-CRISPR-associated-protein	gnl\|CDD\|274040	TIGR02221, CRISPR-associated_protein_Csx1_2, CRISPR-associated protein, TM1812 family. CRISPR is a term for Clustered Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR associated) proteins. This family, represented by TM1812 of Thermotoga maritima, is found also in Vibrio vulnificus YJ016, Nitrosomonas europaea ATCC 19718, a large plasmid of Synechocystis sp. PCC 6803, and Fibrobacter succinogenes S85.	7.89384e-107
NC_005140.1\|WP_043877607.1\|1697290_1698520_+\|CRISPR-associated-protein-Csx16	gnl\|CDD\|200203	TIGR02620, hypothetical_protein, putative CRISPR-associated protein, VVA1548 family. This model represents a conserved domain of about 95 amino acids exclusively in species with CRISPR (Clustered Regularly Interspaced Short Palidromic Repeats). In all bacterial species with members so far (Vibrio vulnificus YJ016, Mannheimia succiniciproducens MBEL55E, and Nitrosomonas europaea ATCC 19718) and but not in the archaeon Methanothermobacter thermautotrophicus str. Delta H, the gene for this protein is in the midst of a cluster of Cas protein gene near CRISPR repeats.	2.86569e-48
NC_005140.1\|WP_043877605.1\|1693775_1694060_+\|CRISPR-associated-endonuclease-Cas2	gnl\|CDD\|187856	cd09725, Cas2_I_II_III, CRISPR/Cas system-associated protein Cas2. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas2 is present in majority of CRISPR/Cas systems along with Cas1; RNAse specific to U-rich regions; Possesses an RRM/ferredoxin fold.	4.04797e-24
NC_005140.1\|WP_011152744.1\|1684477_1685905_-\|hypothetical-protein	gnl\|CDD\|377130	pfam03787, RAMPs, RAMP superfamily. The molecular function of these proteins is not yet known. However, they have been identified and called the RAMP (Repair Associated Mysterious Proteins) superfamily. The members of this family have no known function they are around 300 amino acids in length and have several conserved motifs.	3.75195e-17
NC_005140.1\|WP_011152745.1\|1685901_1687479_-\|hypothetical-protein	gnl\|CDD\|131722	TIGR02674, cas_cyan_RAMP_2, CRISPR-associated RAMP protein, Csx10 family. CRISPR is a widespread repeat family in prokaryotes. At least 45 different protein families occur in prokaryotes only when these repeats are present. This family, a minor CRISPR-associated protein family, seems largely restricted to the Cyanobacteria. It belongs to the RAMP superfamily (pfam03787).	2.80409e-10
NC_005140.1\|WP_011152740.1\|1680209_1680737_+\|peptide-methionine-(S)-S-oxide-reductase-MsrA	gnl\|CDD\|376578	pfam01625, PMSR, Peptide methionine sulfoxide reductase. This enzyme repairs damaged proteins. Methionine sulfoxide in proteins is reduced to methionine.	5.97288e-87
NC_005140.1\|WP_011152746.1\|1687475_1688078_-\|hypothetical-protein	gnl\|CDD\|187857	cd09726, RAMP_I_III, CRISPR/Cas system-associated RAMP superfamily protein. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; RAMP superfamily proteins.	3.81694e-18
NC_005140.1\|WP_011081943.1\|1702517_1702766_+\|DUF3297-family-protein	gnl\|CDD\|371696	pfam11730, DUF3297, Protein of unknown function (DUF3297). This family is expressed in Proteobacteria and Actinobacteria. The function is not known.	1.13889e-44
NC_005140.1\|WP_043877603.1\|1681788_1683951_-\|TIGR03986-family-CRISPR-associated-RAMP-protein	gnl\|CDD\|274902	TIGR03986, CRISPR-associated_protein, CRISPR-associated protein. Members of this protein family, part of the larger RAMP family, are found exclusively in species with CRISPR systems, in local contexts containing other RAMP (Repeat-Associated Mystery Proteins).	2.49111e-167
NC_005140.1\|WP_011081941.1\|1679757_1680213_+\|peptide-methionine-(R)-S-oxide-reductase-MsrB	gnl\|CDD\|376583	pfam01641, SelR, SelR domain. Methionine sulfoxide reduction is an important process, by which cells regulate biological processes and cope with oxidative stress. MsrA, a protein involved in the reduction of methionine sulfoxides in proteins, has been known for four decades and has been extensively characterized with respect to structure and function. However, recent studies revealed that MsrA is only specific for methionine-S-sulfoxides. Because oxidized methionines occur in a mixture of R and S isomers in vivo, it was unclear how stereo-specific MsrA could be responsible for the reduction of all protein methionine sulfoxides. It appears that a second methionine sulfoxide reductase, SelR, evolved that is specific for methionine-R-sulfoxides, the activity that is different but complementary to that of MsrA. Thus, these proteins, working together, could reduce both stereoisomers of methionine sulfoxide. This domain is found both in SelR proteins and fused with the peptide methionine sulfoxide reductase enzymatic domain pfam01625. The domain has two conserved cysteine and histidines. The domain binds both selenium and zinc. The final cysteine is found to be replaced by the rare amino acid selenocysteine in some members of the family. This family has methionine-R-sulfoxide reductase activity.	3.12709e-69
NC_005140.1\|WP_052281496.1\|1695360_1696662_-\|TIGR02584-family-CRISPR-associated-protein	gnl\|CDD\|187817	cd09686, Csx1_III-U, CRISPR/Cas system-associated protein Csx1. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Protein of this family often fused to HTH domain; Some proteins could have an additional fusion with RecB-family nuclease domain; Core domain appears to have a Rossmann-like fold; loosely associated with CRISPR/Cas systems; also known as NE0113 family.	6.5094e-115
NC_005140.1\|WP_011152750.1\|1691703_1693776_+\|CRISPR-associated-endonuclease-Cas1	gnl\|CDD\|187766	cd09634, Cas1_I-II-III, CRISPR/Cas system-associated protein Cas1. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas1 is the most universal CRISPR system protein thought to be involved in spacer integration; Cas1 is metal-dependent deoxyribonuclease, also binds RNA; Shown to possess a unique fold consisting of a N-terminal beta-strand domain and a C-terminal alpha-helical domain.	6.45344e-101

>NC_005140.1|WP_011152748.1|1690470_1691262_+|hypothetical-protein
MRVKPSQRPLILLLILLSSAGVAGVQPGSYPSLAQARLGTHDHTVSSEPNALLHAIERGHAIPLKFDAQFKANSPYLFPSRLYQDEYWRQKAINVTWLKAMQQLVSEFACAEYRYRHRLIETQQCYQEQAKHQQQPKEGMPFFSGQFLQRTLEINQDNRFNQVSYQMWLPSGEQESLRSVLGSVHELGTFFGRLADHRSLVLSVRVNVYQLSNEGGRGDTLTRAPMLYFVLLPTAKALANQPTQREAALYAWQQARVILVGKP
>NC_005140.1|WP_043877604.1|1688074_1689850_-|hypothetical-protein
MYYCYLFEAKSIQAYLFQSNKLRDVISASERLDRLVDSSAESVLGMVLNTAKLSSDLFDVAPDSPQSIYFLRCKGGAFYAYCRSESPLLALRSGWTLTLSQLFPSLIYTDALSQAENLPQAMTLGLKQLNTDRNSPHPCLPLATSLVLRTARTGKGAVPLSRLATQGSVQSERELDIDTELHRQAYQLFGMRDSAALQDSFTPEELKGVVRYPINFETQFPFAGAVDALTRDQRDAIKDMALIHIDGNGLGILLRQLKQVLHAQPVEEYQHAFRAFSAALSAATQKAAQESTRMVYQQVSSEGAYSTVVLPMRPIVLGGDDVTLFCRADLAIDYAETFCIAFQRESQKILAPLYQRYLANSDIKPYLTASGGVLFHKAGHPFPHCHQLVEGLCEQAKILTKSVYGTQSNKVGPAALAFYRVSNATQSDIGALIEQAQTFALSAGEQICLTQCSYFVSMTDDEQAALESELGKPLLVNRSLGKLRDLIQVSNNKVGKAPMSMSKWRQLATLLSQRDFVEAKRLYNRSRALCLESQKVTEFDRRVSALSGETTSEAAWCWKASNQWQTFINDVLLVEHFQPVSIPQVAQEEVE
>NC_005140.1|WP_011152746.1|1687475_1688078_-|hypothetical-protein
MKSYQVTIDIHSEWHVGSGEEGGTYADALVLKNPHNLPFLPGKALKGLFRDSFLVAHDNRWFGGELTTEAIELLFGHQGQVEHTHGALSFSNAELSSEESAYFELYPEHTRHCYRVHFSTAINGQTGVAKQTSLRAMEVAIPLRLYARIELDDQRLDSRMQQQVNEWLEMCSTLILGLGAKRTRGLGQATVSIEPVGVQG
>NC_005140.1|WP_011152745.1|1685901_1687479_-|hypothetical-protein
MKIYYALTTLDSLVLSQTNATTNNHQVLDYIPGSAVLGALAGKLYDSLTDEQSWHLFHSGKVQFGPAYCEIDGEMGWPIPASWHYPKGEAVFEHNSLTHHVKNQAGIDALDLDEAVQFKQCRSGYINSRGKQGSVKQGMVTKTALNRESGAVKDGSLFSYAYLAKGQRFIGWVECDSAEYYDLLEGSLVGQHRIGRSRGTEFGRVSIELLAAPDVLPVSLNERLVLWCLSDCQCVDFQGMPTFTPELCDLVLGAKGTLNQQQSFIRSNSITRFNQKRGGFDSEQLVISKGSVLVFDDVELCEDQLHQLSGQGIGLNRQQGLGWVAVNPSWAYQKGLSEQPLFAAPSFELSSLAAKSAVAASAENSPLIAWIEQQADRQNQHAMELDGAKSLLQAIILAYVSVRKYNRVIHSHQAGPSSSQWRRIAELLREGRLDWQALLFDKKNGICNASNDPLGWGITWHDGQHYVTFSEYFQGLLEQSEVQLSVSQMRRFLEQLCRYDLSVYQELKTAAKDFTLSIKVEEANA
>NC_005140.1|WP_011152744.1|1684477_1685905_-|hypothetical-protein
MSKVNVANLVIETVSPLAITSGLREAAFDTALVRDCNGLPMIPATSIAGVWSHLAEKYFGREIREYWFGRASEGNDDYCRSRFVISHGVLHDQHGQPVRGLVQPRVIDEDGVLKVCVQERPYHRERVAINDRGVAKPHAKFDQIVLPKGLRFSVQVRWEQDGAEPLLALWNLRQMAFGSSTRNGLGQVKLVLSDLERFDLSEGAHIGTRIQHYCRHAPVPENNFLAQEVVGAEHLLAQLPLQALDNWRCGSGAELLGSHGRLEQQVSLITYSEPYWQWQNGQAVWQSAKAVLCGSSIKGILAHRISYHYRRHLQCWAEEISLEASPAQWEEKPAGLNQFFGYSDEHDHEKSLAGIFIVDDSELEYEHTALRYHNAIDRFTGGVRKGALYSEELLFKPRFTLRIWLAEPLSYLQSVRQFDPVFKLALESTLEDLKQGLLPFGAGSGRGVCLVEQSAHEDWITNLHWLVDQNKEVQR
>NC_005140.1|WP_011152743.1|1683965_1684481_-|hypothetical-protein
MTIALYTQLQQQNNQCLSENDRSFPSIGIEMPNIVESHLTIETVQCQRQELFRKIIDFAPQQGWVCYRDGVEIRSEAPTRSDVIEAEYLHRGDSLVVRHLNGETYLLSYLREGHQDGTGVMCYREQKMRLRNDITSSANHVVYRVWFQQSQSGLTQGRWLPKVQQFVGFVD
>NC_005140.1|WP_043877603.1|1681788_1683951_-|TIGR03986-family-CRISPR-associated-RAMP-protein
MSSKIHAPYHFVPLSKWVYMPDWAHLVSHDVPFKDGLSGIIEYTVNNQTPLCVGSEQTKQDDGSSVVKFARDPLKNLVIPSSTMKGMLRSVLEIVGFGKFNQLDDRRFSFRDISDARCNYLSNIIKPYPPKAGWLKFDVARQQWSFTPCQYAKIKHADLKKAFDIEIKNDLPAVKKYQRFPLSFSFQANISQPKGKQKNCWVEQLGKGSTQGHVIFTNKRIISTGKPSDYEFSYFFYSPEPRKVKWQIDQQVQDFFDNHNLEQIEYLKKNPQHELGIPVFALIKGEKIHSIGLAKMPRVSYKNSTKELTEVQNKAHFSDLYFDLAELIFGTLREEGLGLKSRVSFSDAYCTSGSEHMLYSSNLVVLNEPKPTFYPAYIEQDHDNHRAQYNDYDHSQPLSGHKRYIVKRPADRQLESNVVGTNRRVAGSMELCPVGQEFRGKIVFHNLKPVELGAILWCMQLEQGSYHQMGHGKPMGAGVVTVSPTLSVVRSNERDFDGNVDKLVELFVTHMEAKHPNGQWRLSPQLENMLAIGRMDDNVEINTRYMDINKREFQTAKKEFAKLDLFNGLARKEPTSFNPEKCPSEAFASGRLAALFEPTELWQKTIFDAKETRLRTLREEQLAQEERRLKEVKLAGMTEHQRYFVELKEKVSQANPTDRAPLLRDALSHLIGLADPTESDVARELYQLARSYELHKSPKKRVDEHKQLLAKLLDVYEIKQ
>NC_005140.1|WP_011152741.1|1680901_1681792_-|CRISPR-system-precrRNA-processing-endoribonuclease-RAMP-protein-Cas6
MMVLNELASRFELVRFRVSLLLKEDTQLPEFKGSMWHGWFGQVLKAYDGTVYHICFGHFEERQPKPYVVCPVGDNKCHWRKGELIQVEISLFGQACELAHRVVDAIIASTNNPNIGIGGRKVSYQLVSVASVTPEGLKAGLYKTWLSDWAAGSFHHSSTPQELAMQFITPTRIKHHGQLVRYEVPNVGFWINHIIRRLVLLSQFWVLDNEHLVDTIYQEALSLTPPHLDNTESSVLWEDWKRYSKSSHEFQPFGGLVGHVSFFGELHSLVPYFKVGEQLQIGGKTTFGLGRYQLIC
>NC_005140.1|WP_011152740.1|1680209_1680737_+|peptide-methionine-(S)-S-oxide-reductase-MsrA
MNTQLATFGGGCFWCTEAMFSQLKGVLDVKSGYSGGHVKHPCYREVCSGKTGHAEVIQVSFDPDIIRYEALLLVHLTTHNPTTLNRQGADRGTQYRSIILAHDEEQKRIAQQVIAEVAPYFDEPIVTEVVDFEQFYQAETHHQNYYSDNPKKQYCAVVIEPKLRRLRERYADLLG
>NC_005140.1|WP_011081941.1|1679757_1680213_+|peptide-methionine-(R)-S-oxide-reductase-MsrB
MLTWQDIITFTHQGNPQPDTVVRKSDAQWREQLGEAQYYVMRQHGTERPFSNQMCELFEPGLYRCAGCQNLLFDSGSKFDSRTGWPSFAQPMKSNAISYHLDETLARPRIEVRCNQCESHLGHVFPDGPAPSGLRYCVNAVSIEKVNQEAS
>NC_005140.1|WP_011152750.1|1691703_1693776_+|CRISPR-associated-endonuclease-Cas1
MAIHLTIEELQTSWKKVSANKGIAGVDGVTIQTFAIHLDTNLNTLLSAWNHGNYAPSPYRPLTIQPNEKKTRQLAIPTVADRIIHTAIAQKLVAKFEPEFEHISYGYRPNRSYTHAIRHIEQLRNQGYLYVLDADIKGYFDHICHKRLKQILQKYLEDNWVESIMTLLLSQQMPAQTLLFGVELGRGIPQGSPLSPLLANLYLDGFDEALLDRGEQIVRYADDFVVLVTHEQQAQHCLAFVTQYLASLKLQLNTEKTRVVSFQDGFTFLGVSFLDNMVLPLKTHTEKALVNIGKHELEMADDEALSLHSEEDEALNQTLWHSNLPPALRSLQAAIYDDDNVLPIEPDQARIERLSLNHIARLKLVYIHKQGAAVHKRGNRINVFFDGKPLNSIPANTIDMMLCFGAVHLTQAVQRFCLENDISVVWLSQSGQYLGCMSAPFQGDPLLTAAQVNSRADPDVRNHLAKFFIRSKINNALGVMRRQGKKQQRNKEQEKRIVHLREQLDAHQTLASIRGTEGAAAREYFSWFRQQFSADWGFNSRNRQPPKDPINAMLSYGYTLLFHNIRALVEARGLLPHLGYLHGSQPRQPSLVLDLMEGYRPWLVDELVLQLAGKKLITPEQFTTHKNGVLLNREGKRLFIQSLEQRFLSQHQHPTLKIKADTRRLIDIQVLELRHQLLSGQWSLTQQRIR
>NC_005140.1|WP_043877605.1|1693775_1694060_+|CRISPR-associated-endonuclease-Cas2
MSREHYVICYDISERQTRYRVEKALLGYGERVQYSVFECRLTTGQFFALRHELRRWLEDGDRVNYFRLCLHCQRRRLTQGAMVAWQSQPFDYID
>NC_005140.1|WP_011152752.1|1694068_1694347_+|CRISPR-associated-endonuclease-Cas2
MLWLISFDISDDKRRRRAVKLLLGYGNRTQYSVFECLLKRSQLRQIQQKMQAVIEPSDRVLYYPLCGKDALCRYADGAGQVYWPDALYLIDE
>NC_005140.1|WP_052281496.1|1695360_1696662_-|TIGR02584-family-CRISPR-associated-protein
MKKAILLSIAGLTPQVITETLYGIHTEQQENHQWLWPEEIQIITTRLGKEQILLGLLTKDSDGYSQLEKLCHDYQRPVPYIDESTIYVIPDAQGNPVADARSKQDHEALASFIVRHVAELCAQDDIVLHASLAGGRKTMTFFLGYALALFAREQDRLSHVLVDEEYENNRHFYYPTRKTHVIPGRGENSQLDASKANVTLAEIPFIRHKHMLPKESLTCLTTRSYRALTKTQNALQYRESIHLSFNLLQREVSVMDMVVDFRQHPLELAFYAMFATQFKRYGVYHFHKPSEQSLDLHLTDLLLQQLERIAGLPIRDYSTELAQGDKRRFMAEYEQRATALTERDIPMRGGGRQDIARTYHELNAGMSGKFFSDKLNKLKRILSQALVPELADLIMPAQVFDKDNPNQIRPYSTGGQQKSPYGLWLKAEQISIR
>NC_005140.1|WP_043877606.1|1696969_1697260_+|CRISPR-associated-protein-Csx16
MNWFISRHAGAKQWAVEQGLEVDCFISHLDIAQIGEGDKVIGTLPVQIAASVCEKGARYFHLSLTVPEIWRGKELSLEQMKACQAKIEEFSVRICS
>NC_005140.1|WP_043877607.1|1697290_1698520_+|CRISPR-associated-protein-Csx16
MNYLICKYSGAQEWLSQQGIHIDHVVDSIHLIDVSQGDKVYGDVPVSLLRDLSKKQVSYWEIKADIHHSVDPTTVEAEYLKRVDAQLIKTELHIGLSGYFKRCRHYVADRWKRMGHWYRRAERSPRLIWAYTTLSLLFFAWFGDLAGGSHLFEWAIGRSSSTGVLDVWPTLISLTGYVLFSSLLIRAGRGFLPGLRSVKVTKTTKARRVLLLNLSHLPNLSEVNGQFHVSLRNQDQETTYHFQGELLTDLAKLNEIEAQGFRWNGTQLLRALAKHIDRVELLVLLSTKDLGSHRNEMGSHHFAPRVKQLLSQYVDHYRCKIVVEPRLLHPQNVGETYDILNEVLSDLIVKEHIRDQDICLDITGGTAAMSCAAAMATIHRNSQFQYVSTDGKGEVYQQDLQLTVSPAKA
>NC_005140.1|WP_011152756.1|1698532_1699708_+|TIGR02221-family-CRISPR-associated-protein
MKTFVTFIGRGQQDRSSEVKRYQTAVYQFEDGSLTPPVTFVGKTLIEHLAPQKVIVAGTSGSMWDELCPEGLSEDFHLLLMERADQQSVDHVLLKELQDTLNHSSIGPRFHLVLLPDSASESQQVAFFSAITEHIDHHDVITLDITHGFRFMPILAFACIQFLQFVKRVEVDDLLYALLRFNQPSPICSLKQLLEIGKWVNALGQFDHSGDLRVFESLLEKQCWDPQHIRQLCRGAFLERTTNSSDARAQLLPLLNYKWRTPIGELISDEFQSRVSWVRKPKRGERECELAHLYLQRNDFLRALIYGLEGRISKTVDAYQLGDDFQDREAAKNILKDEYGEPFHHLLQLRNNLAHGVRTRTTGKRSWINQAVTDPNLLPDRITALFKQLDI
>NC_005140.1|WP_011152757.1|1699933_1702207_+|hypothetical-protein
MHKMFKTTALFGSLSILFGCGGGSGSDSSGQPSQPIREVIAMDGFLKNAVVFEDANNNLRWDENEPLLGLTNEFGKLKINTPKDSQIGVMTINAHSELANKLAAIDDRYQGIETIDMDIPDKAMGKEVVFVAPKGVNILSPFSHLVSSIAFSEQIDASEAQQKLETELNTHGFELNTLGNYLESGSKAQHKLAQLFTDSFGTHQHKVSELWPGFVEESVFAVNQLSDVQLADPTMRPSVDGDMNTPVQFNRKLVRNKSAIAQLYTVWSQMPDISLGDTGEFFRIDLSALEVNGQPTPMLTDPDVKEGKVTYLVQNHYSAPLSTSTTLVNGVTVSIDHDGSSLVLSSERIQHVGTVPVMLHAVDRDQNGEIVQYQVFLLEVRTSSANKAPYVVANAEENLQATVDSDWIVQKGQEFNYNINVADLFADVENDSLNIDVSGSALDIGLNGVTKDGVITISGIPVKSYQEDHTRHTLTISATDNFNSRQASVTLTLPEIWHGELNQTNPLIGKNWYYIDSVEEDGQVKNYCRFINFSNGKVTQTLANVYDYHGCQQASQSVIQSTFYTETTLTSLKERLLFNTKIYTMRYRQKVQSGEAYAVSIDLYEGAKNKRVFMFYSDINEVKQRLDLDSVNANDSATFHWTLPLEDRLVSATIRSVVSDQTIELAFIPPKGITLTCEDLRNLWEISGGLYGISNSSWGSRECTEVLEGDNIYPQFTFSLSRGDNLANGESYSVNVDVNRKSTFDYIEPLKFNLKKD
>NC_005140.1|WP_011152758.1|1702365_1702512_+|hypothetical-protein
MKEIGAMFSQLKGGFFLRANLPGHVPQAESLNRALALSTMAHFLAISG
>NC_005140.1|WP_011081943.1|1702517_1702766_+|DUF3297-family-protein
MNDTTAKPALPDRLSGNARSPFFVKECFDHQIGIRFNGKERNDVEEYCVSEGWIKIASPKAKDRYGNPMLIQLKGTVEAYYV

You can click texts colored in the table to view more detailed information

Click the colored protein region to show detailed information

Crispr_ID: NC_005140_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_005140_2

1694586-1695317

TypeIII

Consensus_repeat	Method
GTTTCAGACATGCCCGGTTTAGACGGGATTAAGAC	PILER-CR
GTTTCAGACATGCCCGGTTTAGACGGGATTAAGAC	CRISPRCasFinder
GTTTCAGACATGCCCGGTTTAGACGGGATTAAGAC	CRT

10 spacers

cas2,cas1,cas10,csm3gr7,csx10gr5,csx1,csx16

The CRISPR arrays of NC_005140_2

>merge|NC_005140|2|1694586-1695317|PILER-CR,CRISPRCasFinder,CRT
GTTTCAGACATGCCCGGTTTAGACGGGATTAAGACAAAACCACAAGGTTTTCGTAGCCGTTTTGTAGCCGTTTCAGACATGCCCGGTTTAGACGGGATTAAGACATGCACCTTTTGCATTTAAGATGGTTTCCTGCTGTTTCAGACATGCCCGGTTTAGACGGGATTAAGACATCAAAGGCTTTACCCTTGATGCATCCTTCAACATGTTTCAGACATGCCCGGTTTAGACGGGATTAAGACTCTAGTAACCAACGACGCAACATGCTTCGAGCATTGTTTCAGACATGCCCGGTTTAGACGGGATTAAGACTCGTTATGCTGGTTGCTGTTCAGCTCTAATAATGTTTCAGACATGCCCGGTTTAGACGGGATTAAGACACCAGCCTCGCAGTAGCGATTCTTTAATCTGGTTGGTTTCAGACATGCCCGGTTTAGACGGGATTAAGACAACTCTTTATCATCCATGTAAACAGCAAATGCAGTTGGTTTCAGACATGCCCGGTTTAGACGGGATTAAGACTATGATCTGTACGATGACCTTGTCCAAAAACATGTTTCAGACATGCCCGGTTTAGACGGGATTAAGACACGTTTAGAAAACGAAATCTATTTTTGTTCACCTCAAGTTTCAGACATGCCCGGTTTAGACGGGATTAAGACGCTAAAAACTTTAATCAAATTGGTAAACATTTCCAGTTTCAGACATGCCCGGTTTCTGCTTAGCAAAAGA

>NC_005140|2|1|1694586-1695247|PILER-CR
GTTTCAGACATGCCCGGTTTAGACGGGATTAAGAC	AAAACCACAAGGTTTTCGTAGCCGTTTTGTAGCC
GTTTCAGACATGCCCGGTTTAGACGGGATTAAGAC	ATGCACCTTTTGCATTTAAGATGGTTTCCTGCT
GTTTCAGACATGCCCGGTTTAGACGGGATTAAGAC	ATCAAAGGCTTTACCCTTGATGCATCCTTCAACAT
GTTTCAGACATGCCCGGTTTAGACGGGATTAAGAC	TCTAGTAACCAACGACGCAACATGCTTCGAGCATT
GTTTCAGACATGCCCGGTTTAGACGGGATTAAGAC	TCGTTATGCTGGTTGCTGTTCAGCTCTAATAAT
GTTTCAGACATGCCCGGTTTAGACGGGATTAAGAC	ACCAGCCTCGCAGTAGCGATTCTTTAATCTGGTTG
GTTTCAGACATGCCCGGTTTAGACGGGATTAAGAC	AACTCTTTATCATCCATGTAAACAGCAAATGCAGTTG
GTTTCAGACATGCCCGGTTTAGACGGGATTAAGAC	TATGATCTGTACGATGACCTTGTCCAAAAACAT
GTTTCAGACATGCCCGGTTTAGACGGGATTAAGAC	ACGTTTAGAAAACGAAATCTATTTTTGTTCACCTCAA
GTTTCAGACATGCCCGGTTTAGACGGGATTAAGAC

>NC_005140|2|2|1694586-1695247|CRISPRCasFinder
GTTTCAGACATGCCCGGTTTAGACGGGATTAAGAC	AAAACCACAAGGTTTTCGTAGCCGTTTTGTAGCC
GTTTCAGACATGCCCGGTTTAGACGGGATTAAGAC	ATGCACCTTTTGCATTTAAGATGGTTTCCTGCT
GTTTCAGACATGCCCGGTTTAGACGGGATTAAGAC	ATCAAAGGCTTTACCCTTGATGCATCCTTCAACAT
GTTTCAGACATGCCCGGTTTAGACGGGATTAAGAC	TCTAGTAACCAACGACGCAACATGCTTCGAGCATT
GTTTCAGACATGCCCGGTTTAGACGGGATTAAGAC	TCGTTATGCTGGTTGCTGTTCAGCTCTAATAAT
GTTTCAGACATGCCCGGTTTAGACGGGATTAAGAC	ACCAGCCTCGCAGTAGCGATTCTTTAATCTGGTTG
GTTTCAGACATGCCCGGTTTAGACGGGATTAAGAC	AACTCTTTATCATCCATGTAAACAGCAAATGCAGTTG
GTTTCAGACATGCCCGGTTTAGACGGGATTAAGAC	TATGATCTGTACGATGACCTTGTCCAAAAACAT
GTTTCAGACATGCCCGGTTTAGACGGGATTAAGAC	ACGTTTAGAAAACGAAATCTATTTTTGTTCACCTCAA
GTTTCAGACATGCCCGGTTTAGACGGGATTAAGAC

>NC_005140|2|1|1694586-1695317|CRT
GTTTCAGACATGCCCGGTTTAGACGGGATTAAGAC	AAAACCACAAGGTTTTCGTAGCCGTTTTGTAGCC
GTTTCAGACATGCCCGGTTTAGACGGGATTAAGAC	ATGCACCTTTTGCATTTAAGATGGTTTCCTGCT
GTTTCAGACATGCCCGGTTTAGACGGGATTAAGAC	ATCAAAGGCTTTACCCTTGATGCATCCTTCAACAT
GTTTCAGACATGCCCGGTTTAGACGGGATTAAGAC	TCTAGTAACCAACGACGCAACATGCTTCGAGCATT
GTTTCAGACATGCCCGGTTTAGACGGGATTAAGAC	TCGTTATGCTGGTTGCTGTTCAGCTCTAATAAT
GTTTCAGACATGCCCGGTTTAGACGGGATTAAGAC	ACCAGCCTCGCAGTAGCGATTCTTTAATCTGGTTG
GTTTCAGACATGCCCGGTTTAGACGGGATTAAGAC	AACTCTTTATCATCCATGTAAACAGCAAATGCAGTTG
GTTTCAGACATGCCCGGTTTAGACGGGATTAAGAC	TATGATCTGTACGATGACCTTGTCCAAAAACAT
GTTTCAGACATGCCCGGTTTAGACGGGATTAAGAC	ACGTTTAGAAAACGAAATCTATTTTTGTTCACCTCAA
GTTTCAGACATGCCCGGTTTAGACGGGATTAAGAC	GCTAAAAACTTTAATCAAATTGGTAAACATTTCCA
GTTTCAGACATGCCCGGTTTCTGCTTAGCAAAAGA

Protein	Signature genes	Signature genes Name	Protein_function
NC_005140.1\|WP_011152745.1\|1685901_1687479_-\|hypothetical-protein	csx10gr5	cls000748_csx10gr5_CAS-III-D	gnl\|CDD\|131722
NC_005140.1\|WP_043877604.1\|1688074_1689850_-\|hypothetical-protein	cas10	cls000686_cas10_CAS-III	unknown
NC_005140.1\|WP_011152748.1\|1690470_1691262_+\|hypothetical-protein	unknown	unknown	unknown
NC_005140.1\|WP_011152750.1\|1691703_1693776_+\|CRISPR-associated-endonuclease-Cas1	cas1	cd09634_cas1_CAS-I:CAS-II:CAS-III:CAS-V	gnl\|CDD\|187766
NC_005140.1\|WP_011152746.1\|1687475_1688078_-\|hypothetical-protein	csm3gr7	cd09726_csm3gr7_CAS-III-D	gnl\|CDD\|187857
NC_005140.1\|WP_011152758.1\|1702365_1702512_+\|hypothetical-protein	unknown	unknown	unknown
NC_005140.1\|WP_043877606.1\|1696969_1697260_+\|CRISPR-associated-protein-Csx16	csx16	pfam09652_csx16_CAS-I:CAS-III	gnl\|CDD\|200203
NC_005140.1\|WP_011152762.1\|1703299_1704652_-\|carbohydrate-ABC-transporter-substrate-binding-protein	unknown	unknown	gnl\|CDD\|224567
NC_005140.1\|WP_011152757.1\|1699933_1702207_+\|hypothetical-protein	unknown	unknown	unknown
NC_005140.1\|WP_011152743.1\|1683965_1684481_-\|hypothetical-protein	unknown	unknown	unknown
NC_005140.1\|WP_043877605.1\|1693775_1694060_+\|CRISPR-associated-endonuclease-Cas2	cas2	cd09725_cas2_CAS-I:CAS-II:CAS-III:CAS-V	gnl\|CDD\|187856
NC_005140.1\|WP_043877607.1\|1697290_1698520_+\|CRISPR-associated-protein-Csx16	csx16	pfam09652_csx16_CAS-I:CAS-III	gnl\|CDD\|200203
NC_005140.1\|WP_011152756.1\|1698532_1699708_+\|TIGR02221-family-CRISPR-associated-protein	csx1	cd09668_csx1_CAS-III	gnl\|CDD\|274040
NC_005140.1\|WP_015728397.1\|1704660_1706640_-\|methyl-accepting-chemotaxis-protein	unknown	unknown	gnl\|CDD\|223910
NC_005140.1\|WP_015728395.1\|1702965_1703223_+\|DUF2999-family-protein	unknown	unknown	gnl\|CDD\|288110
NC_005140.1\|WP_011152752.1\|1694068_1694347_+\|CRISPR-associated-endonuclease-Cas2	cas2	cd09725_cas2_CAS-I:CAS-II:CAS-III:CAS-V	gnl\|CDD\|187856
NC_005140.1\|WP_011081943.1\|1702517_1702766_+\|DUF3297-family-protein	unknown	unknown	gnl\|CDD\|371696
NC_005140.1\|WP_043877603.1\|1681788_1683951_-\|TIGR03986-family-CRISPR-associated-RAMP-protein	csm3gr7	cls000253_csm3gr7_CAS-III-A:CAS-III-D	gnl\|CDD\|274902
NC_005140.1\|WP_052281496.1\|1695360_1696662_-\|TIGR02584-family-CRISPR-associated-protein	csx1	cd09686_csx1_CAS-III	gnl\|CDD\|187817
NC_005140.1\|WP_011152744.1\|1684477_1685905_-\|hypothetical-protein	csm3gr7	cd09726_csm3gr7_CAS-III-D	gnl\|CDD\|377130

Protein	Cas_name	Cas_description	E-value	Identity	Coverage
NC_005140.1\|WP_011152745.1\|1685901_1687479_-\|hypothetical-protein	csx10gr5	cls000748_csx10gr5_CAS-III-D	2.5e-36	119.8	0.0
NC_005140.1\|WP_043877604.1\|1688074_1689850_-\|hypothetical-protein	cas10	cls000686_cas10_CAS-III	0	1427.8	4.7
NC_005140.1\|WP_011152750.1\|1691703_1693776_+\|CRISPR-associated-endonuclease-Cas1	cas1	cd09634_cas1_CAS-I:CAS-II:CAS-III:CAS-V	6.7e-94	309.2	0.0
NC_005140.1\|WP_011152746.1\|1687475_1688078_-\|hypothetical-protein	csm3gr7	cd09726_csm3gr7_CAS-III-D	5.2e-19	64.1	0.0
NC_005140.1\|WP_043877606.1\|1696969_1697260_+\|CRISPR-associated-protein-Csx16	csx16	pfam09652_csx16_CAS-I:CAS-III	5.6e-44	143.1	0.0
NC_005140.1\|WP_043877605.1\|1693775_1694060_+\|CRISPR-associated-endonuclease-Cas2	cas2	cd09725_cas2_CAS-I:CAS-II:CAS-III:CAS-V	7.6e-24	78.5	0.2
NC_005140.1\|WP_043877607.1\|1697290_1698520_+\|CRISPR-associated-protein-Csx16	csx16	pfam09652_csx16_CAS-I:CAS-III	1.9e-38	125.4	0.7
NC_005140.1\|WP_011152756.1\|1698532_1699708_+\|TIGR02221-family-CRISPR-associated-protein	csx1	cd09668_csx1_CAS-III	2.3e-87	287.2	0.0
NC_005140.1\|WP_011152752.1\|1694068_1694347_+\|CRISPR-associated-endonuclease-Cas2	cas2	cd09725_cas2_CAS-I:CAS-II:CAS-III:CAS-V	6.8e-24	78.7	0.1
NC_005140.1\|WP_043877603.1\|1681788_1683951_-\|TIGR03986-family-CRISPR-associated-RAMP-protein	csm3gr7	cls000253_csm3gr7_CAS-III-A:CAS-III-D	4.1e-196	648.4	0.1
NC_005140.1\|WP_052281496.1\|1695360_1696662_-\|TIGR02584-family-CRISPR-associated-protein	csx1	cd09686_csx1_CAS-III	2.1e-100	329.6	0.0
NC_005140.1\|WP_011152744.1\|1684477_1685905_-\|hypothetical-protein	csm3gr7	cd09726_csm3gr7_CAS-III-D	4.4e-28	93.6	0.0

Protein	Function_ID	Function_description	E-value
NC_005140.1\|WP_011152745.1\|1685901_1687479_-\|hypothetical-protein	gnl\|CDD\|131722	TIGR02674, cas_cyan_RAMP_2, CRISPR-associated RAMP protein, Csx10 family. CRISPR is a widespread repeat family in prokaryotes. At least 45 different protein families occur in prokaryotes only when these repeats are present. This family, a minor CRISPR-associated protein family, seems largely restricted to the Cyanobacteria. It belongs to the RAMP superfamily (pfam03787).	2.80409e-10
NC_005140.1\|WP_015728395.1\|1702965_1703223_+\|DUF2999-family-protein	gnl\|CDD\|288110	pfam11212, DUF2999, Protein of unknown function (DUF2999). This family of proteins with unknown function appears to be restricted to Gammaproteobacteria.	3.46868e-34
NC_005140.1\|WP_011152750.1\|1691703_1693776_+\|CRISPR-associated-endonuclease-Cas1	gnl\|CDD\|187766	cd09634, Cas1_I-II-III, CRISPR/Cas system-associated protein Cas1. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas1 is the most universal CRISPR system protein thought to be involved in spacer integration; Cas1 is metal-dependent deoxyribonuclease, also binds RNA; Shown to possess a unique fold consisting of a N-terminal beta-strand domain and a C-terminal alpha-helical domain.	6.45344e-101
NC_005140.1\|WP_011152746.1\|1687475_1688078_-\|hypothetical-protein	gnl\|CDD\|187857	cd09726, RAMP_I_III, CRISPR/Cas system-associated RAMP superfamily protein. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; RAMP superfamily proteins.	3.81694e-18
NC_005140.1\|WP_043877606.1\|1696969_1697260_+\|CRISPR-associated-protein-Csx16	gnl\|CDD\|200203	TIGR02620, hypothetical_protein, putative CRISPR-associated protein, VVA1548 family. This model represents a conserved domain of about 95 amino acids exclusively in species with CRISPR (Clustered Regularly Interspaced Short Palidromic Repeats). In all bacterial species with members so far (Vibrio vulnificus YJ016, Mannheimia succiniciproducens MBEL55E, and Nitrosomonas europaea ATCC 19718) and but not in the archaeon Methanothermobacter thermautotrophicus str. Delta H, the gene for this protein is in the midst of a cluster of Cas protein gene near CRISPR repeats.	5.79554e-53
NC_005140.1\|WP_011152762.1\|1703299_1704652_-\|carbohydrate-ABC-transporter-substrate-binding-protein	gnl\|CDD\|224567	COG1653, UgpB, ABC-type sugar transport system, periplasmic component [Carbohydrate transport and metabolism].	1.3357e-47
NC_005140.1\|WP_043877605.1\|1693775_1694060_+\|CRISPR-associated-endonuclease-Cas2	gnl\|CDD\|187856	cd09725, Cas2_I_II_III, CRISPR/Cas system-associated protein Cas2. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas2 is present in majority of CRISPR/Cas systems along with Cas1; RNAse specific to U-rich regions; Possesses an RRM/ferredoxin fold.	4.04797e-24
NC_005140.1\|WP_043877607.1\|1697290_1698520_+\|CRISPR-associated-protein-Csx16	gnl\|CDD\|200203	TIGR02620, hypothetical_protein, putative CRISPR-associated protein, VVA1548 family. This model represents a conserved domain of about 95 amino acids exclusively in species with CRISPR (Clustered Regularly Interspaced Short Palidromic Repeats). In all bacterial species with members so far (Vibrio vulnificus YJ016, Mannheimia succiniciproducens MBEL55E, and Nitrosomonas europaea ATCC 19718) and but not in the archaeon Methanothermobacter thermautotrophicus str. Delta H, the gene for this protein is in the midst of a cluster of Cas protein gene near CRISPR repeats.	2.86569e-48
NC_005140.1\|WP_011152756.1\|1698532_1699708_+\|TIGR02221-family-CRISPR-associated-protein	gnl\|CDD\|274040	TIGR02221, CRISPR-associated_protein_Csx1_2, CRISPR-associated protein, TM1812 family. CRISPR is a term for Clustered Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR associated) proteins. This family, represented by TM1812 of Thermotoga maritima, is found also in Vibrio vulnificus YJ016, Nitrosomonas europaea ATCC 19718, a large plasmid of Synechocystis sp. PCC 6803, and Fibrobacter succinogenes S85.	7.89384e-107
NC_005140.1\|WP_015728397.1\|1704660_1706640_-\|methyl-accepting-chemotaxis-protein	gnl\|CDD\|223910	COG0840, Tar, Methyl-accepting chemotaxis protein [Cell motility and secretion / Signal transduction mechanisms].	1.01513e-60
NC_005140.1\|WP_011152752.1\|1694068_1694347_+\|CRISPR-associated-endonuclease-Cas2	gnl\|CDD\|187856	cd09725, Cas2_I_II_III, CRISPR/Cas system-associated protein Cas2. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas2 is present in majority of CRISPR/Cas systems along with Cas1; RNAse specific to U-rich regions; Possesses an RRM/ferredoxin fold.	1.30813e-22
NC_005140.1\|WP_011081943.1\|1702517_1702766_+\|DUF3297-family-protein	gnl\|CDD\|371696	pfam11730, DUF3297, Protein of unknown function (DUF3297). This family is expressed in Proteobacteria and Actinobacteria. The function is not known.	1.13889e-44
NC_005140.1\|WP_043877603.1\|1681788_1683951_-\|TIGR03986-family-CRISPR-associated-RAMP-protein	gnl\|CDD\|274902	TIGR03986, CRISPR-associated_protein, CRISPR-associated protein. Members of this protein family, part of the larger RAMP family, are found exclusively in species with CRISPR systems, in local contexts containing other RAMP (Repeat-Associated Mystery Proteins).	2.49111e-167
NC_005140.1\|WP_052281496.1\|1695360_1696662_-\|TIGR02584-family-CRISPR-associated-protein	gnl\|CDD\|187817	cd09686, Csx1_III-U, CRISPR/Cas system-associated protein Csx1. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Protein of this family often fused to HTH domain; Some proteins could have an additional fusion with RecB-family nuclease domain; Core domain appears to have a Rossmann-like fold; loosely associated with CRISPR/Cas systems; also known as NE0113 family.	6.5094e-115
NC_005140.1\|WP_011152744.1\|1684477_1685905_-\|hypothetical-protein	gnl\|CDD\|377130	pfam03787, RAMPs, RAMP superfamily. The molecular function of these proteins is not yet known. However, they have been identified and called the RAMP (Repair Associated Mysterious Proteins) superfamily. The members of this family have no known function they are around 300 amino acids in length and have several conserved motifs.	3.75195e-17

>NC_005140.1|WP_011152752.1|1694068_1694347_+|CRISPR-associated-endonuclease-Cas2
MLWLISFDISDDKRRRRAVKLLLGYGNRTQYSVFECLLKRSQLRQIQQKMQAVIEPSDRVLYYPLCGKDALCRYADGAGQVYWPDALYLIDE
>NC_005140.1|WP_043877605.1|1693775_1694060_+|CRISPR-associated-endonuclease-Cas2
MSREHYVICYDISERQTRYRVEKALLGYGERVQYSVFECRLTTGQFFALRHELRRWLEDGDRVNYFRLCLHCQRRRLTQGAMVAWQSQPFDYID
>NC_005140.1|WP_011152750.1|1691703_1693776_+|CRISPR-associated-endonuclease-Cas1
MAIHLTIEELQTSWKKVSANKGIAGVDGVTIQTFAIHLDTNLNTLLSAWNHGNYAPSPYRPLTIQPNEKKTRQLAIPTVADRIIHTAIAQKLVAKFEPEFEHISYGYRPNRSYTHAIRHIEQLRNQGYLYVLDADIKGYFDHICHKRLKQILQKYLEDNWVESIMTLLLSQQMPAQTLLFGVELGRGIPQGSPLSPLLANLYLDGFDEALLDRGEQIVRYADDFVVLVTHEQQAQHCLAFVTQYLASLKLQLNTEKTRVVSFQDGFTFLGVSFLDNMVLPLKTHTEKALVNIGKHELEMADDEALSLHSEEDEALNQTLWHSNLPPALRSLQAAIYDDDNVLPIEPDQARIERLSLNHIARLKLVYIHKQGAAVHKRGNRINVFFDGKPLNSIPANTIDMMLCFGAVHLTQAVQRFCLENDISVVWLSQSGQYLGCMSAPFQGDPLLTAAQVNSRADPDVRNHLAKFFIRSKINNALGVMRRQGKKQQRNKEQEKRIVHLREQLDAHQTLASIRGTEGAAAREYFSWFRQQFSADWGFNSRNRQPPKDPINAMLSYGYTLLFHNIRALVEARGLLPHLGYLHGSQPRQPSLVLDLMEGYRPWLVDELVLQLAGKKLITPEQFTTHKNGVLLNREGKRLFIQSLEQRFLSQHQHPTLKIKADTRRLIDIQVLELRHQLLSGQWSLTQQRIR
>NC_005140.1|WP_011152748.1|1690470_1691262_+|hypothetical-protein
MRVKPSQRPLILLLILLSSAGVAGVQPGSYPSLAQARLGTHDHTVSSEPNALLHAIERGHAIPLKFDAQFKANSPYLFPSRLYQDEYWRQKAINVTWLKAMQQLVSEFACAEYRYRHRLIETQQCYQEQAKHQQQPKEGMPFFSGQFLQRTLEINQDNRFNQVSYQMWLPSGEQESLRSVLGSVHELGTFFGRLADHRSLVLSVRVNVYQLSNEGGRGDTLTRAPMLYFVLLPTAKALANQPTQREAALYAWQQARVILVGKP
>NC_005140.1|WP_043877604.1|1688074_1689850_-|hypothetical-protein
MYYCYLFEAKSIQAYLFQSNKLRDVISASERLDRLVDSSAESVLGMVLNTAKLSSDLFDVAPDSPQSIYFLRCKGGAFYAYCRSESPLLALRSGWTLTLSQLFPSLIYTDALSQAENLPQAMTLGLKQLNTDRNSPHPCLPLATSLVLRTARTGKGAVPLSRLATQGSVQSERELDIDTELHRQAYQLFGMRDSAALQDSFTPEELKGVVRYPINFETQFPFAGAVDALTRDQRDAIKDMALIHIDGNGLGILLRQLKQVLHAQPVEEYQHAFRAFSAALSAATQKAAQESTRMVYQQVSSEGAYSTVVLPMRPIVLGGDDVTLFCRADLAIDYAETFCIAFQRESQKILAPLYQRYLANSDIKPYLTASGGVLFHKAGHPFPHCHQLVEGLCEQAKILTKSVYGTQSNKVGPAALAFYRVSNATQSDIGALIEQAQTFALSAGEQICLTQCSYFVSMTDDEQAALESELGKPLLVNRSLGKLRDLIQVSNNKVGKAPMSMSKWRQLATLLSQRDFVEAKRLYNRSRALCLESQKVTEFDRRVSALSGETTSEAAWCWKASNQWQTFINDVLLVEHFQPVSIPQVAQEEVE
>NC_005140.1|WP_011152746.1|1687475_1688078_-|hypothetical-protein
MKSYQVTIDIHSEWHVGSGEEGGTYADALVLKNPHNLPFLPGKALKGLFRDSFLVAHDNRWFGGELTTEAIELLFGHQGQVEHTHGALSFSNAELSSEESAYFELYPEHTRHCYRVHFSTAINGQTGVAKQTSLRAMEVAIPLRLYARIELDDQRLDSRMQQQVNEWLEMCSTLILGLGAKRTRGLGQATVSIEPVGVQG
>NC_005140.1|WP_011152745.1|1685901_1687479_-|hypothetical-protein
MKIYYALTTLDSLVLSQTNATTNNHQVLDYIPGSAVLGALAGKLYDSLTDEQSWHLFHSGKVQFGPAYCEIDGEMGWPIPASWHYPKGEAVFEHNSLTHHVKNQAGIDALDLDEAVQFKQCRSGYINSRGKQGSVKQGMVTKTALNRESGAVKDGSLFSYAYLAKGQRFIGWVECDSAEYYDLLEGSLVGQHRIGRSRGTEFGRVSIELLAAPDVLPVSLNERLVLWCLSDCQCVDFQGMPTFTPELCDLVLGAKGTLNQQQSFIRSNSITRFNQKRGGFDSEQLVISKGSVLVFDDVELCEDQLHQLSGQGIGLNRQQGLGWVAVNPSWAYQKGLSEQPLFAAPSFELSSLAAKSAVAASAENSPLIAWIEQQADRQNQHAMELDGAKSLLQAIILAYVSVRKYNRVIHSHQAGPSSSQWRRIAELLREGRLDWQALLFDKKNGICNASNDPLGWGITWHDGQHYVTFSEYFQGLLEQSEVQLSVSQMRRFLEQLCRYDLSVYQELKTAAKDFTLSIKVEEANA
>NC_005140.1|WP_011152744.1|1684477_1685905_-|hypothetical-protein
MSKVNVANLVIETVSPLAITSGLREAAFDTALVRDCNGLPMIPATSIAGVWSHLAEKYFGREIREYWFGRASEGNDDYCRSRFVISHGVLHDQHGQPVRGLVQPRVIDEDGVLKVCVQERPYHRERVAINDRGVAKPHAKFDQIVLPKGLRFSVQVRWEQDGAEPLLALWNLRQMAFGSSTRNGLGQVKLVLSDLERFDLSEGAHIGTRIQHYCRHAPVPENNFLAQEVVGAEHLLAQLPLQALDNWRCGSGAELLGSHGRLEQQVSLITYSEPYWQWQNGQAVWQSAKAVLCGSSIKGILAHRISYHYRRHLQCWAEEISLEASPAQWEEKPAGLNQFFGYSDEHDHEKSLAGIFIVDDSELEYEHTALRYHNAIDRFTGGVRKGALYSEELLFKPRFTLRIWLAEPLSYLQSVRQFDPVFKLALESTLEDLKQGLLPFGAGSGRGVCLVEQSAHEDWITNLHWLVDQNKEVQR
>NC_005140.1|WP_011152743.1|1683965_1684481_-|hypothetical-protein
MTIALYTQLQQQNNQCLSENDRSFPSIGIEMPNIVESHLTIETVQCQRQELFRKIIDFAPQQGWVCYRDGVEIRSEAPTRSDVIEAEYLHRGDSLVVRHLNGETYLLSYLREGHQDGTGVMCYREQKMRLRNDITSSANHVVYRVWFQQSQSGLTQGRWLPKVQQFVGFVD
>NC_005140.1|WP_043877603.1|1681788_1683951_-|TIGR03986-family-CRISPR-associated-RAMP-protein
MSSKIHAPYHFVPLSKWVYMPDWAHLVSHDVPFKDGLSGIIEYTVNNQTPLCVGSEQTKQDDGSSVVKFARDPLKNLVIPSSTMKGMLRSVLEIVGFGKFNQLDDRRFSFRDISDARCNYLSNIIKPYPPKAGWLKFDVARQQWSFTPCQYAKIKHADLKKAFDIEIKNDLPAVKKYQRFPLSFSFQANISQPKGKQKNCWVEQLGKGSTQGHVIFTNKRIISTGKPSDYEFSYFFYSPEPRKVKWQIDQQVQDFFDNHNLEQIEYLKKNPQHELGIPVFALIKGEKIHSIGLAKMPRVSYKNSTKELTEVQNKAHFSDLYFDLAELIFGTLREEGLGLKSRVSFSDAYCTSGSEHMLYSSNLVVLNEPKPTFYPAYIEQDHDNHRAQYNDYDHSQPLSGHKRYIVKRPADRQLESNVVGTNRRVAGSMELCPVGQEFRGKIVFHNLKPVELGAILWCMQLEQGSYHQMGHGKPMGAGVVTVSPTLSVVRSNERDFDGNVDKLVELFVTHMEAKHPNGQWRLSPQLENMLAIGRMDDNVEINTRYMDINKREFQTAKKEFAKLDLFNGLARKEPTSFNPEKCPSEAFASGRLAALFEPTELWQKTIFDAKETRLRTLREEQLAQEERRLKEVKLAGMTEHQRYFVELKEKVSQANPTDRAPLLRDALSHLIGLADPTESDVARELYQLARSYELHKSPKKRVDEHKQLLAKLLDVYEIKQ
>NC_005140.1|WP_052281496.1|1695360_1696662_-|TIGR02584-family-CRISPR-associated-protein
MKKAILLSIAGLTPQVITETLYGIHTEQQENHQWLWPEEIQIITTRLGKEQILLGLLTKDSDGYSQLEKLCHDYQRPVPYIDESTIYVIPDAQGNPVADARSKQDHEALASFIVRHVAELCAQDDIVLHASLAGGRKTMTFFLGYALALFAREQDRLSHVLVDEEYENNRHFYYPTRKTHVIPGRGENSQLDASKANVTLAEIPFIRHKHMLPKESLTCLTTRSYRALTKTQNALQYRESIHLSFNLLQREVSVMDMVVDFRQHPLELAFYAMFATQFKRYGVYHFHKPSEQSLDLHLTDLLLQQLERIAGLPIRDYSTELAQGDKRRFMAEYEQRATALTERDIPMRGGGRQDIARTYHELNAGMSGKFFSDKLNKLKRILSQALVPELADLIMPAQVFDKDNPNQIRPYSTGGQQKSPYGLWLKAEQISIR
>NC_005140.1|WP_043877606.1|1696969_1697260_+|CRISPR-associated-protein-Csx16
MNWFISRHAGAKQWAVEQGLEVDCFISHLDIAQIGEGDKVIGTLPVQIAASVCEKGARYFHLSLTVPEIWRGKELSLEQMKACQAKIEEFSVRICS
>NC_005140.1|WP_043877607.1|1697290_1698520_+|CRISPR-associated-protein-Csx16
MNYLICKYSGAQEWLSQQGIHIDHVVDSIHLIDVSQGDKVYGDVPVSLLRDLSKKQVSYWEIKADIHHSVDPTTVEAEYLKRVDAQLIKTELHIGLSGYFKRCRHYVADRWKRMGHWYRRAERSPRLIWAYTTLSLLFFAWFGDLAGGSHLFEWAIGRSSSTGVLDVWPTLISLTGYVLFSSLLIRAGRGFLPGLRSVKVTKTTKARRVLLLNLSHLPNLSEVNGQFHVSLRNQDQETTYHFQGELLTDLAKLNEIEAQGFRWNGTQLLRALAKHIDRVELLVLLSTKDLGSHRNEMGSHHFAPRVKQLLSQYVDHYRCKIVVEPRLLHPQNVGETYDILNEVLSDLIVKEHIRDQDICLDITGGTAAMSCAAAMATIHRNSQFQYVSTDGKGEVYQQDLQLTVSPAKA
>NC_005140.1|WP_011152756.1|1698532_1699708_+|TIGR02221-family-CRISPR-associated-protein
MKTFVTFIGRGQQDRSSEVKRYQTAVYQFEDGSLTPPVTFVGKTLIEHLAPQKVIVAGTSGSMWDELCPEGLSEDFHLLLMERADQQSVDHVLLKELQDTLNHSSIGPRFHLVLLPDSASESQQVAFFSAITEHIDHHDVITLDITHGFRFMPILAFACIQFLQFVKRVEVDDLLYALLRFNQPSPICSLKQLLEIGKWVNALGQFDHSGDLRVFESLLEKQCWDPQHIRQLCRGAFLERTTNSSDARAQLLPLLNYKWRTPIGELISDEFQSRVSWVRKPKRGERECELAHLYLQRNDFLRALIYGLEGRISKTVDAYQLGDDFQDREAAKNILKDEYGEPFHHLLQLRNNLAHGVRTRTTGKRSWINQAVTDPNLLPDRITALFKQLDI
>NC_005140.1|WP_011152757.1|1699933_1702207_+|hypothetical-protein
MHKMFKTTALFGSLSILFGCGGGSGSDSSGQPSQPIREVIAMDGFLKNAVVFEDANNNLRWDENEPLLGLTNEFGKLKINTPKDSQIGVMTINAHSELANKLAAIDDRYQGIETIDMDIPDKAMGKEVVFVAPKGVNILSPFSHLVSSIAFSEQIDASEAQQKLETELNTHGFELNTLGNYLESGSKAQHKLAQLFTDSFGTHQHKVSELWPGFVEESVFAVNQLSDVQLADPTMRPSVDGDMNTPVQFNRKLVRNKSAIAQLYTVWSQMPDISLGDTGEFFRIDLSALEVNGQPTPMLTDPDVKEGKVTYLVQNHYSAPLSTSTTLVNGVTVSIDHDGSSLVLSSERIQHVGTVPVMLHAVDRDQNGEIVQYQVFLLEVRTSSANKAPYVVANAEENLQATVDSDWIVQKGQEFNYNINVADLFADVENDSLNIDVSGSALDIGLNGVTKDGVITISGIPVKSYQEDHTRHTLTISATDNFNSRQASVTLTLPEIWHGELNQTNPLIGKNWYYIDSVEEDGQVKNYCRFINFSNGKVTQTLANVYDYHGCQQASQSVIQSTFYTETTLTSLKERLLFNTKIYTMRYRQKVQSGEAYAVSIDLYEGAKNKRVFMFYSDINEVKQRLDLDSVNANDSATFHWTLPLEDRLVSATIRSVVSDQTIELAFIPPKGITLTCEDLRNLWEISGGLYGISNSSWGSRECTEVLEGDNIYPQFTFSLSRGDNLANGESYSVNVDVNRKSTFDYIEPLKFNLKKD
>NC_005140.1|WP_011152758.1|1702365_1702512_+|hypothetical-protein
MKEIGAMFSQLKGGFFLRANLPGHVPQAESLNRALALSTMAHFLAISG
>NC_005140.1|WP_011081943.1|1702517_1702766_+|DUF3297-family-protein
MNDTTAKPALPDRLSGNARSPFFVKECFDHQIGIRFNGKERNDVEEYCVSEGWIKIASPKAKDRYGNPMLIQLKGTVEAYYV
>NC_005140.1|WP_015728395.1|1702965_1703223_+|DUF2999-family-protein
MNPILAMLKENNISDEQINELFQTLTQNPLAAMATIAQLGLPQEQLQMLMAQVMQNPALIKEAVEELGLDFSKVEEAKAKLQQPQ
>NC_005140.1|WP_011152762.1|1703299_1704652_-|carbohydrate-ABC-transporter-substrate-binding-protein
MINKWIGALGLLVCSQVMASELVIESWRADDKALWEQKIIPAFEASHPGIKVTFRPVKNVNYMPTLWENLKAGKAGDLITCRPFDDSLALFKAGHLAEITEMAGMENFPSFAQAPWQTDSGAQTFCVPMASVIHGFFYNKQIFNQLGLSVPKTRDQFFSVLDKVKADGRYVPLAMSGSESWVSSELGFQNIGPNYWKGEDGRLALINGQERLDDGQYVQVFEELARWRRYLGTGGENRDYGATNDLFTSGKAAFYVAGSWEIAPFTDKLDFGVMPPPVANQGDGCFFTDHTDIGMGMNPASKNPQAAMAFLQWLTTPQFAELYTNSLPGFFSLSNHFFEVSNPAAREMMEWRDQCDSTIRVATQILSRGQPKLGDELAEVSQAVLLGKMAPKAAATRLENGLKDWYAPHKNSKAKGQECQCSAVTPLATSSVSMTESAVVSVEGEESLSE
>NC_005140.1|WP_015728397.1|1704660_1706640_-|methyl-accepting-chemotaxis-protein
MSLSIVQRISAGFVLMLLLLILLGVISTLKIQGINDGLSEVSDRATPLVVAVAGLKEALQESNRWVLEYRASEEAAELPQLSSRFKSQQARFRELSQEMNQFTSAEESQAQFQQVLQATNQFYADSDKVLAKHGEWVDALVKRRELEIAFIRLEDTYQWAADLLLQQSSSQRSMRNKAELITSGIARDLKNIRRADAKTDLNALEKVLSKDIEMARKRLERVLVPEDVKARYVANLNRLQELALGKQGLLETMRRAQQLENDLVIQNQQVDTSLSNSLAKLDDMARAAGTIAERSRTLADEAVSSANFWIMAVSAISAAVALIIGYTTAMSIKNPLQKINKELAYMAKGDMTRRINYQTGCEFGELSRSIDMLADKTGELLSQITAGSRHLVDEASRSAEISERAMARVQEQKSQTDQVAAAITELEVSATEVARSTDGAKDEVDRADAEAKSGRQKVANTRKITEQLAHDMEAAVGITHKLGEFSNNIGSILDVIRGIAEQTNLLALNAAIEAARAGDAGRGFAVVADEVRALATRTQTSTEEIQKMIENLQHSSKEVVEVMGRSQDQTRTCVEQTREMDTALQSIAERMSAIKEMADQVAHAAQEQILVSQSVAHHVTGISEVAHETEREARESASSSEVLADLAAKQQQLIAHFKV

You can click texts colored in the table to view more detailed information

Click the colored protein region to show detailed information

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NC_005140_2	2.8\|1695108\|33\|NC_005140\|PILER-CR,CRISPRCasFinder,CRT	1695108-1695140	33	NZ_CP007648	Lactobacillus salivarius strain JCM1046 plasmid pMP1046B, complete sequence	54303-54335	8	0.758

1. spacer 2.8|1695108|33|NC_005140|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP007648 (Lactobacillus salivarius strain JCM1046 plasmid pMP1046B, complete sequence) position: , mismatch: 8, identity: 0.758

tatgatctgtacgatgaccttgtccaaaaacat	CRISPR spacer
tggactgagtatgatgaccttgcccaaaaacat	Protospacer
*. . *  ***.**********.**********

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

918830 : 973560

Vibrio_phage(43.33%)

terminase,integrase,holin

attL 947790:947807|attR 969228:969245

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_043877517.1\|918830_931892_-	PLxRFG domain-containing protein	A0A240F4T3	Ochrobactrum_phage	0.0e+00	29.2
WP_011152141.1\|932009_933530_-	hypothetical protein	M4MHC7	Vibrio_phage	7.6e-42	35.4
WP_043877651.1\|933529_933769_-	hypothetical protein	NA	NA	NA	NA
WP_011152143.1\|933772_934201_-	hypothetical protein	A0A1I9KFD7	Aeromonas_phage	3.3e-19	47.5
WP_011152144.1\|934205_934862_-	hypothetical protein	A0A1I9KFE8	Aeromonas_phage	7.1e-37	44.2
WP_011152145.1\|934862_935291_-	hypothetical protein	NA	NA	NA	NA
WP_011152147.1\|935262_935832_-	hypothetical protein	NA	NA	NA	NA
WP_011152148.1\|935848_937081_-	hypothetical protein	NA	NA	NA	NA
WP_011152149.1\|937077_940047_-	DUF1983 domain-containing protein	A0A1I9KGC4	Aeromonas_phage	3.0e-34	54.0
WP_193343218.1\|940046_941654_-	hypothetical protein	A0A1I9KFD2	Aeromonas_phage	5.4e-131	45.7
WP_011152151.1\|941717_942620_-	hypothetical protein	A0A2I7RR76	Vibrio_phage	1.4e-54	41.1
WP_011152152.1\|942616_946090_-	hypothetical protein	M4M9Z4	Vibrio_phage	6.5e-121	34.5
WP_011152153.1\|946089_946719_-	hypothetical protein	Q08J85	Stx2-converting_phage	1.9e-23	32.9
WP_011152154.1\|946718_947315_-	hypothetical protein	NA	NA	NA	NA
WP_011152155.1\|947317_947767_-	hypothetical protein	A0A2R2Z354	Escherichia_phage	9.4e-25	46.6
947790:947807	attL	NA	NA	NA	NA
WP_011152156.1\|947827_948208_-	hypothetical protein	M4MCI2	Vibrio_phage	1.6e-09	35.8
WP_011152157.1\|948228_949434_-	DUF4043 family protein	A0A2L1IV46	Escherichia_phage	2.4e-123	55.6
WP_193343219.1\|949500_950526_-	ATPase	A0A2L1IV47	Escherichia_phage	2.1e-27	33.3
WP_011152159.1\|950648_951239_-	hypothetical protein	A0A2I7RB79	Vibrio_phage	1.6e-27	50.4
WP_039507672.1\|951323_951506_-	hypothetical protein	NA	NA	NA	NA
WP_011152162.1\|951585_951744_-	hypothetical protein	NA	NA	NA	NA
WP_043877518.1\|951755_952274_-	glycoside hydrolase family 108 protein	H9C0H1	Vibrio_phage	9.8e-58	60.9
WP_026130473.1\|952433_952739_-\|holin	phage holin family protein	R9TR41	Vibrio_phage	1.5e-18	44.2
WP_043877519.1\|952867_954955_-	hypothetical protein	A0A1U9AJF2	Stx1_converting_phage	2.8e-204	58.8
WP_011152166.1\|954954_956652_-\|terminase	terminase	A0A1I9KFB6	Aeromonas_phage	2.7e-221	64.5
WP_011152167.1\|956644_957496_-	hypothetical protein	NA	NA	NA	NA
WP_011152169.1\|957873_959052_-\|integrase	site-specific integrase	A0A067ZJC5	Vibrio_phage	1.8e-75	40.0
WP_017789209.1\|959052_959217_-	hypothetical protein	NA	NA	NA	NA
WP_011152171.1\|959206_960016_-	hypothetical protein	NA	NA	NA	NA
WP_011152173.1\|960260_960722_-	VRR-NUC domain-containing protein	M4SRS1	Psychrobacter_phage	2.1e-11	33.6
WP_155116722.1\|960718_961741_-	DUF968 domain-containing protein	R9TRM9	Vibrio_phage	4.4e-62	39.7
WP_011152175.1\|962216_963260_-	hypothetical protein	A0A2I7QZV1	Vibrio_phage	4.6e-22	42.0
WP_011152177.1\|963664_963919_-	helix-turn-helix domain-containing protein	A0A0M3LQ90	Mannheimia_phage	2.0e-11	50.7
WP_011152178.1\|964080_964725_+	LexA family transcriptional regulator	K7PK07	Enterobacteria_phage	3.4e-28	35.3
WP_011152179.1\|965080_965269_+	hypothetical protein	NA	NA	NA	NA
WP_043877520.1\|965278_965830_+	hypothetical protein	NA	NA	NA	NA
WP_011152181.1\|965795_966323_+	PadR family transcriptional regulator	H9EB19	Vibrio_phage	2.0e-13	32.0
WP_011152182.1\|966337_966979_+	AAA family ATPase	J9Q7R7	Salmonella_phage	2.0e-15	29.4
WP_043877521.1\|966978_967260_+	hypothetical protein	NA	NA	NA	NA
WP_011152184.1\|967271_967490_+	AlpA family phage regulatory protein	NA	NA	NA	NA
WP_011152185.1\|967486_968422_+	hypothetical protein	A0A2I7R7C8	Vibrio_phage	7.0e-06	27.0
WP_017789197.1\|968794_969220_+	hypothetical protein	NA	NA	NA	NA
WP_011152189.1\|969264_970263_+	nucleoid-associated protein YejK	A0A1V0E8C0	Vibrio_phage	6.0e-88	52.0
969228:969245	attR	NA	NA	NA	NA
WP_011152190.1\|970358_970844_+	AP2 domain-containing protein	NA	NA	NA	NA
WP_011152191.1\|971057_971396_+	hypothetical protein	A0A240F4V4	Ochrobactrum_phage	2.1e-21	46.0
WP_011152192.1\|971395_971578_+	ANR family transcriptional regulator	NA	NA	NA	NA
WP_043877522.1\|971852_972140_+	restriction alleviation protein, Lar family	NA	NA	NA	NA
WP_011152193.1\|972151_972310_+	hypothetical protein	NA	NA	NA	NA
WP_039546560.1\|973170_973560_+	hypothetical protein	A0A2K8HWN7	Pseudomonas_phage	4.5e-31	56.5

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. NC_005139

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Click the colored protein region to show detailed information

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection

2. NC_005140

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection