CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NC_012491	Brevibacillus brevis NBRC 100599, complete genome	2 crisprs	csa3,WYL,cas14j,RT,DEDDh,Cas14u_CAS-V,DinG,cas3	1	0	8	0

Results visualization

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CRISPR-Cas detection and classification

Crispr_ID: NC_012491_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_012491_1

502645-502759

Orphan

Consensus_repeat	Method
CTGCGACTGAATTCGCAAGTGAAACAAA	CRISPRCasFinder

1 spacers

csa3

The CRISPR arrays of NC_012491_1

>merge|NC_012491|1|502645-502759|CRISPRCasFinder
CTGCGACTGAATTCGCAAGTGAAACAAACGTATCAGAGGTTCGTCGTCAGAACCAACAATCCGCACAACGCTCTGCTTCCAAAGGTGCTGCGACTGAATTCGCAAGTGAGACAAA

>NC_012491|1|1|502645-502759|CRISPRCasFinder
CTGCGACTGAATTCGCAAGTGAAACAAA	CGTATCAGAGGTTCGTCGTCAGAACCAACAATCCGCACAACGCTCTGCTTCCAAAGGTG
CTGCGACTGAATTCGCAAGTGAGACAAA

Protein	Signature genes	Signature genes Name	Protein_function
NC_012491.1\|WP_012684240.1\|505067_506399_+\|IS3-family-transposase	unknown	unknown	gnl\|CDD\|222853
NC_012491.1\|WP_012684244.1\|511074_511503_+\|anti-sigma-regulatory-factor	unknown	unknown	gnl\|CDD\|340411
NC_012491.1\|WP_012684239.1\|503632_504670_+\|outer-membrane-lipoprotein-sorting-protein	unknown	unknown	gnl\|CDD\|225390
NC_012491.1\|WP_012684231.1\|497654_498947_+\|arsenic-transporter	unknown	unknown	gnl\|CDD\|185342
NC_012491.1\|WP_007721089.1\|510212_510512_+\|CopG-family-ribbon-helix-helix-protein	unknown	unknown	gnl\|CDD\|223932
NC_012491.1\|WP_012684243.1\|508779_509982_+\|alanine-racemase	unknown	unknown	gnl\|CDD\|143481
NC_012491.1\|WP_012684230.1\|496834_497548_+\|SDR-family-oxidoreductase	unknown	unknown	gnl\|CDD\|235914
NC_012491.1\|WP_012684229.1\|496248_496800_+\|NAD(P)H-dependent-oxidoreductase	unknown	unknown	gnl\|CDD\|376808
NC_012491.1\|WP_012684238.1\|502981_503368_+\|holo-ACP-synthase	unknown	unknown	gnl\|CDD\|234610
NC_012491.1\|WP_012684228.1\|495596_496220_+\|ester-cyclase	unknown	unknown	gnl\|CDD\|377824
NC_012491.1\|WP_012684234.1\|500085_501705_+\|GMC-family-oxidoreductase	unknown	unknown	gnl\|CDD\|225186
NC_012491.1\|WP_012684245.1\|511508_512510_+\|PP2C-family-protein-serine/threonine-phosphatase	unknown	unknown	gnl\|CDD\|225118
NC_012491.1\|WP_012684232.1\|499079_499469_+\|hypothetical-protein	unknown	unknown	unknown
NC_012491.1\|WP_012684242.1\|508336_508777_+\|hypothetical-protein	unknown	unknown	unknown
NC_012491.1\|WP_012684236.1\|502158_502410_-\|NrdH-redoxin	unknown	unknown	gnl\|CDD\|239274
NC_012491.1\|WP_012684241.1\|506777_508151_+\|hypothetical-protein	unknown	unknown	unknown
NC_012491.1\|WP_012684235.1\|501801_502137_+\|winged-helix-turn-helix-transcriptional-regulator	csa3	COG0640_csa3_CAS-I-A	gnl\|CDD\|238042
NC_012491.1\|WP_005830205.1\|510515_510866_+\|type-II-toxin-antitoxin-system-PemK/MazF-family-toxin	unknown	unknown	gnl\|CDD\|367091
NC_012491.1\|WP_012684233.1\|499496_500099_+\|gluconate-2-dehydrogenase-subunit-3-family-protein	unknown	unknown	gnl\|CDD\|379295
NC_012491.1\|WP_007721121.1\|495087_495426_-\|helix-turn-helix-transcriptional-regulator	unknown	unknown	gnl\|CDD\|224647

Protein	Function_ID	Function_description	E-value
NC_012491.1\|WP_012684244.1\|511074_511503_+\|anti-sigma-regulatory-factor	gnl\|CDD\|340411	cd16934, HATPase_RsbT-like, Histidine kinase-like ATPase domain of the anti sigma-B factor Bacillus subtilis serine/threonine-protein kinase RsbT, and related domains. This family includes the histidine kinase-like ATPase (HATPase) domain of Bacillus subtilis serine/threonine-protein kinase RsbT, a component of the stressosome signaling complex of Bacillus subtilis. The stressosome is formed from multiple copies of three proteins, a sensor protein RsbR, a scaffold protein RsbS, and RsbT, and responds to environmental changes by initiating a protein partner switching cascade. Stress perception increases the phosphorylation of RsbR and RsbS, by RsbT. Subsequent dissociation of RsbT from the stressosome activates the sigma-B cascade, leading to the release of the alternative sigma factor, sigma-B.	1.51614e-41
NC_012491.1\|WP_012684239.1\|503632_504670_+\|outer-membrane-lipoprotein-sorting-protein	gnl\|CDD\|225390	COG2834, LolA, Outer membrane lipoprotein-sorting protein [Cell envelope biogenesis, outer membrane].	2.36857e-25
NC_012491.1\|WP_012684231.1\|497654_498947_+\|arsenic-transporter	gnl\|CDD\|185342	PRK15445, PRK15445, arsenical efflux pump membrane protein ArsB.	0
NC_012491.1\|WP_007721089.1\|510212_510512_+\|CopG-family-ribbon-helix-helix-protein	gnl\|CDD\|223932	COG0864, NikR, Predicted transcriptional regulators containing the CopG/Arc/MetJ DNA-binding domain and a metal-binding domain [Transcription].	3.24091e-21
NC_012491.1\|WP_012684243.1\|508779_509982_+\|alanine-racemase	gnl\|CDD\|143481	cd00430, PLPDE_III_AR, Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzyme Alanine Racemase. This family includes predominantly bacterial alanine racemases (AR), some serine racemases (SerRac), and putative bifunctional enzymes containing N-terminal UDP-N-acetylmuramoyl-tripeptide:D-alanyl-D-alanine ligase (murF) and C-terminal AR domains. These proteins are fold type III PLP-dependent enzymes that play essential roles in peptidoglycan biosynthesis. AR catalyzes the interconversion between L- and D-alanine, which is an essential component of the peptidoglycan layer of bacterial cell walls. SerRac converts L-serine into its D-enantiomer (D-serine) for peptidoglycan synthesis. murF catalyzes the addition of D-Ala-D-Ala to UDPMurNAc-tripeptide, the final step in the synthesis of the cytoplasmic precursor of bacterial cell wall peptidoglycan. Members of this family contain an N-terminal PLP-binding TIM-barrel domain and a C-terminal beta-sandwich domain. They exist as homodimers with active sites that lie at the interface between the TIM barrel domain of one subunit and the beta-sandwich domain of the other subunit. AR and other members of this family require dimer formation and the presence of the PLP cofactor for catalytic activity. Fungal ARs and eukaryotic serine racemases, which are fold types I and II PLP-dependent enzymes respectively, are excluded from this family.	3.74342e-179
NC_012491.1\|WP_012684230.1\|496834_497548_+\|SDR-family-oxidoreductase	gnl\|CDD\|235914	PRK07041, PRK07041, SDR family oxidoreductase.	6.80203e-91
NC_012491.1\|WP_012684229.1\|496248_496800_+\|NAD(P)H-dependent-oxidoreductase	gnl\|CDD\|376808	pfam02525, Flavodoxin_2, Flavodoxin-like fold. This family consists of a domain with a flavodoxin-like fold. The family includes bacterial and eukaryotic NAD(P)H dehydrogenase (quinone) EC:1.6.99.2. These enzymes catalyze the NAD(P)H-dependent two-electron reductions of quinones and protect cells against damage by free radicals and reactive oxygen species. This enzyme uses a FAD co-factor. The equation for this reaction is:- NAD(P)H + acceptor <=> NAD(P)(+) + reduced acceptor. This enzyme is also involved in the bioactivation of prodrugs used in chemotherapy. The family also includes acyl carrier protein phosphodiesterase EC:3.1.4.14. This enzyme converts holo-ACP to apo-ACP by hydrolytic cleavage of the phosphopantetheine residue from ACP. This family is related to pfam03358 and pfam00258.	2.74161e-44
NC_012491.1\|WP_012684238.1\|502981_503368_+\|holo-ACP-synthase	gnl\|CDD\|234610	PRK00070, acpS, 4'-phosphopantetheinyl transferase; Provisional.	1.38842e-44
NC_012491.1\|WP_012684228.1\|495596_496220_+\|ester-cyclase	gnl\|CDD\|377824	pfam07366, SnoaL, SnoaL-like polyketide cyclase. This family includes SnoaL a polyketide cyclase involved in nogalamycin biosynthesis. This family was formerly known as DUF1486. The proteins in this family adopt a distorted alpha-beta barrel fold. Structural data together with site-directed mutagenesis experiments have shown that SnoaL has a different mechanism to that of the classical aldolase for catalyzing intramolecular aldol condensation.	3.96211e-47
NC_012491.1\|WP_012684234.1\|500085_501705_+\|GMC-family-oxidoreductase	gnl\|CDD\|225186	COG2303, BetA, Choline dehydrogenase and related flavoproteins [Amino acid transport and metabolism].	2.21506e-72
NC_012491.1\|WP_012684245.1\|511508_512510_+\|PP2C-family-protein-serine/threonine-phosphatase	gnl\|CDD\|225118	COG2208, RsbU, Serine phosphatase RsbU, regulator of sigma subunit [Signal transduction mechanisms / Transcription].	8.37066e-61
NC_012491.1\|WP_012684240.1\|505067_506399_+\|IS3-family-transposase	gnl\|CDD\|222853	PHA02517, PHA02517, putative transposase OrfB; Reviewed.	1.16256e-39
NC_012491.1\|WP_012684236.1\|502158_502410_-\|NrdH-redoxin	gnl\|CDD\|239274	cd02976, NrdH, NrdH-redoxin (NrdH) family; NrdH is a small monomeric protein with a conserved redox active CXXC motif within a TRX fold, characterized by a glutaredoxin (GRX)-like sequence and TRX-like activity profile. In vitro, it displays protein disulfide reductase activity that is dependent on TRX reductase, not glutathione (GSH). It is part of the NrdHIEF operon, where NrdEF codes for class Ib ribonucleotide reductase (RNR-Ib), an efficient enzyme at low oxygen levels. Under these conditions when GSH is mostly conjugated to spermidine, NrdH can still function and act as a hydrogen donor for RNR-Ib. It has been suggested that the NrdHEF system may be the oldest RNR reducing system, capable of functioning in a microaerophilic environment, where GSH was not yet available. NrdH from Corynebacterium ammoniagenes can form domain-swapped dimers, although it is unknown if this happens in vivo. Domain-swapped dimerization, which results in the blocking of the TRX reductase binding site, could be a mechanism for regulating the oxidation state of the protein.	1.9609e-14
NC_012491.1\|WP_012684235.1\|501801_502137_+\|winged-helix-turn-helix-transcriptional-regulator	gnl\|CDD\|238042	cd00090, HTH_ARSR, Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to dissociate from DNA in the presence of metal ions.	8.66553e-21
NC_012491.1\|WP_005830205.1\|510515_510866_+\|type-II-toxin-antitoxin-system-PemK/MazF-family-toxin	gnl\|CDD\|367091	pfam02452, PemK_toxin, PemK-like, MazF-like toxin of type II toxin-antitoxin system. PemK is a growth inhibitor in E. coli known to bind to the promoter region of the Pem operon, auto-regulating synthesis. This family represents the toxin molecule of a typical bacterial toxin-antitoxin system pairing. The family includes a number of different toxins, such as MazF, Kid, PemK, ChpA, ChpB and ChpAK.	7.47696e-41
NC_012491.1\|WP_012684233.1\|499496_500099_+\|gluconate-2-dehydrogenase-subunit-3-family-protein	gnl\|CDD\|379295	pfam13618, Gluconate_2-dh3, Gluconate 2-dehydrogenase subunit 3. This family corresponds to subunit 3 of the Gluconate 2-dehydrogenase enzyme that catalyzes the conversion of gluconate to 2-dehydro-D-gluconate EC:1.1.99.3.	1.0871e-23
NC_012491.1\|WP_007721121.1\|495087_495426_-\|helix-turn-helix-transcriptional-regulator	gnl\|CDD\|224647	COG1733, COG1733, Predicted transcriptional regulators [Transcription].	8.94367e-38

>NC_012491.1|WP_012684236.1|502158_502410_-|NrdH-redoxin
MAHKVIIYTQVTCGPCQEEKMWLTSNNIAFEDRDIRQNEAFFQEAIQLGASMTPVTYIEKENGEQIVIHGFDKEELKKALDLN
>NC_012491.1|WP_012684235.1|501801_502137_+|winged-helix-turn-helix-transcriptional-regulator
MEMDLMQVLFLSETYKLLGDKTRLTIMALLQVQSLCVRDLVEILQTSQPSVSQHLAKLKTHGLVKERRKGPWVYYSVNTECSPEVKQILSNLPDMSPVVKQKSAASEPSFG
>NC_012491.1|WP_012684234.1|500085_501705_+|GMC-family-oxidoreductase
MTSHDHHTITHRPTPVDQRKYADDADVCIVGAGAAGGVLAYELAKAGLRVVVLEAGPFWDPQHDFASDELSMRRLAWQETRLVAGKDPLRLGHNNSGRGIGGGTVHFTGVFLRFHESDFKTKTVDGVGEDWPITYQDLAPYYDKIEREIAVSGPNHFPWGSFQGPYPYPVREPISANAQLFREGCEKLGIESVVAPLAILSGPFDGRPPCINRGFCNQGCMPNAKYSGLIHHIPKAIAEGAEVLADCMVTEILMAGDRVGGVLFNHNGLTYRQMARVVILAGFVVETPRLLLSSANAQFPQGLANSSGWVGKAIMPHSSHDVYGRLPEEVRLYKGTPVLALTQHFYETDRERGFARGYTLSAHGSRPVGMAAAIAAEREDGSYLWGKQLRETMLDYNMYARITLVGEVLPHPDNRVTLSGEKDEYGMPIPTVTFSYQENDKQLYKHAIGQMNRIIEAMGGHPEHVVSDTAHLMGGCRMGNDRETSVVNEYGQSHDIPNLFIAGASTFVTSSGSNPTNTVMALAARTADKIIEAMKKQDV
>NC_012491.1|WP_012684233.1|499496_500099_+|gluconate-2-dehydrogenase-subunit-3-family-protein
MEKPGRYPSYDVWDQHTEWDAHTRKVVGARRMPAIANQFFTKHESLLLQTVVGVLVNDHRLEVLTFVVEHLDNTTASNIGESQRKVGIPPKKEFYRSGLKGIDAESHAAYGTDFVALKLDQQEAVLQHVANGGIQNQEAWKDFAPADFFKRLLHDTVSAYYSHPLVWSDIGYGGPAYPRGYVRVEKGLTDPWEAKTNDES
>NC_012491.1|WP_012684232.1|499079_499469_+|hypothetical-protein
MWHGWPIERVLILFTGLAFALIAVQVTLFHSRQNFRHWAMWIPVLELPVFAVTAIVLSFVNAGWLRWVFALMMVVGMVGGLYGAYLHTVGVGQRVGGYSQGQNFLVGPPVILPLLITAMSALGLLALFW
>NC_012491.1|WP_012684231.1|497654_498947_+|arsenic-transporter
MVWISCFLFLITLTLVIWQPRGLSIGYPAVGGALLALAIGVVTIGDVAEVTSIVWNATLALIGIIIISLVLDEVGFFEWAALHMARFAKGNGRLMFVYVILLGSLVSALFTNDGAALILTPIVLAQVRALKLDGKTVLAFVMASGFIADTSSLPFVISNLVNIVSADYFDIGFAAYAAKMIIPTLFSIGGSLLVLYLYFRKSIPAQIDLSHLKNPEEAIRDHRMFRLAWPILAVLLIGFFISESIHTPVSIIIAGAAIIFCLAARKSEAIAMRRIMKEAPWVVVVFSIGMYVVVWGLHNAKLTDLVKDALDWFMGHGLLATTLGTGFLAAALSSVMNNLPTVIFNALAIAGTQADGVLREAMIYANVIGSDLGPKITPIGSLATLLWLHVLGRKDVTITWGQYFRTGVILTVPTLMFTLLGLYLTLVYFS
>NC_012491.1|WP_012684230.1|496834_497548_+|SDR-family-oxidoreductase
MLHNQKIVIIGGSSGIGLETAKQAVALGAGVIIASRSEEKLQKAKESLGSKASAYTLDITDEQQVQAFFEKVGTFDHLVVSAAETSGGSFLQTDTAQARKLFDNKFWGQYYAAKYGAPKISTNGSITLFSGVVAYKAMIGSSALGAVNAAVSNLGQTLALELAPIRVNIVSPGIIDTPSRSKMPEDVRENFYATLADKLPVKRVGQAKDVAQSVLYLLQNSFVTGTVLHVEGGHILL
>NC_012491.1|WP_012684229.1|496248_496800_+|NAD(P)H-dependent-oxidoreductase
MKKILIINGHQKYGSSEGKLNQTLTDHMVRLLEKENHVRTTIIQNGYQIEEEHEKFLWADMVIYQTPIYWFSVPGLMKTYMDEVYAYGLFFKGANQYGRGGLLTGKKYMFSTTWNAPEKAFNDPTQFFNGESLEDAISHLHRVQEFLGMQPVKSFACYDVIKNPQIDRFVSELEAHLKQVLSF
>NC_012491.1|WP_012684228.1|495596_496220_+|ester-cyclase
MIPLTKKMSSIAGIAVIFGTMLFTTACATDSKTSAYDKQTAVLSAKTDVQLLKDLPQPVSMTIDSSLDSTKATEMVQAAQRFYGFWNTGNEELIAQTVSPSFIDNTLPKGRPQGPDGLLFASRNFRKAVPDLQCKVEDLLVVGDKVTARLSFTGTSKGEFMGKPLVGKPIQFMAIDVLRIQDGKLVEDWHLEDNLTFMQQIGVLAEN
>NC_012491.1|WP_007721121.1|495087_495426_-|helix-turn-helix-transcriptional-regulator
MNVLEPIELNKGTPGQPCPIAKTLDVIGTKWTFLIIRDLLIEGTLRFSDLLKSMDGISPKTLSLRLKELEEHGILERKVFPEVPPRVEYTLTEKGKRLEGIFIELKRFGLHL
>NC_012491.1|WP_012684238.1|502981_503368_+|holo-ACP-synthase
MIIGTGVDIVEIERIATLIKRQERAIKHFLTTDEQQLLHGKSETRQAEMVAGRFAAKEAGAKALGTGIGAVLSFLDMEILPNHLGKPVMTIKNEVYSKLDLDPTRVHIHVSISHSQSHAIAQVIVEER
>NC_012491.1|WP_012684239.1|503632_504670_+|outer-membrane-lipoprotein-sorting-protein
MKRVALPLVLLLVFTLFLGGCFGQKTPEDVVSDLNGALGKMTGYKSQAVLTMQTGSTPMEYDVQVWYEKPTNYRVALTSKQRGITQIILRNNEGVFVLTPHLNKSFRFQSGWPENNGPLYLYETLAKSIIDDTERQMKMEEKQYVFEVKANYSGNRSLTKQKIWLTEDFKPTHAEIMDASMNPLVRIDFTDFSFNPMFDKDAFDKERNMTTSSLTTIPTMAQTNGQVVKQPNSQFGVIVPTYMPEGVKQGDIEPVTRDGERKVILTYKGTYNYKVIEGRPTAASVSYEQGMPVNLGFTVGVLAQTGENQRLLTWELDGIEYTIAGDLPEEEMVNVAQSTYGLSAK
>NC_012491.1|WP_012684240.1|505067_506399_+|IS3-family-transposase
MSKNRISFTEHEIHMLEKNQNVLRVTGKNITYSSMFKFTAVQAYREGQTPIEIFLQAGFPLEIIGRHTPKKCLHRWRKVYTTFGEAGLIEERRGKGSTGRKSEGELSAEEKLRRAEARIRLLEAENELLKKLEALERQTNKTLSSPERFQLISLVLRKHGLKRVTRYLCQIAEVSSSGYYRWCSAEEQRQIREEADERDFLLIKEHFETRKGRAGVLVIKMRLERMNGAVMNHKKIRRLMQKFKLVTLIRKANPYRKMAKATQEHRTCPNLLKRQFDQGIPEKVLLTDITYLRYGTGQWAYLSCVKDGATKQILAHYLSSTLELSLVKRTLDLLIKRLDGNVHPDAIFHSDQGMHYTHLTTRRLIAEAGFKQSMSRKGNCWDNASMESFFGHMKDELEYKDCVSLQELRQRVNEYVTYYNSERYQWTLKKMTPDETRNHLIAA
>NC_012491.1|WP_012684241.1|506777_508151_+|hypothetical-protein
MFSKTKMGMLMGTMAVVLSLGSIGGAMAADSAKPTSLNKPVEVKFKTGKMGHHGGVGFKENKELLSLLKLDADKLKEELAAGKTLAAIAQAQGVDTADVVALLVDQQEAKLKGAVTAGKLTQEQADKLSENLSDRVKEQVENSKPDKGFGRGGFIGGFEKNEELLSLLKLDADKLQEELKADKSLATIAEAQGVSVDDLVALLVKQQETKLKEAVAAGKLTQEQADKMNEKANERVKEMVQNTHHGRGPGREMGFEKNQELLSLLKLDADKLQEELKAEKSLATIAETQGVSVDDLVALLVKQQETKLKEAVAAGKLTQEQADKMNEKASERVKEMVQNTHHGRGPGKGMGIEKNEELLSLLKLDADKLKEEQKAGKSLATIAKEQGVEVDDVIKLLVGQHETKLKEAVKAGKLTQEQADKRSEELTAMVQKMVDGSFEKVVFPKHEKEKKDQKETM
>NC_012491.1|WP_012684242.1|508336_508777_+|hypothetical-protein
MKKPSNEVLYQEASTYKDMLLRKSWKMRINETVMFVLGMMILAQFFPTNDTRFKVLVFAIAIAVVGLSPFMYKSVLRPVYKLTKTHLIISLSGQEKSYPLSEVEQIYEGRHFYLVGGKKESLMVSRQFLSHLNERLFYYKKGNKRR
>NC_012491.1|WP_012684243.1|508779_509982_+|alanine-racemase
MKSFCRDTWVEVDLDAIRANLETFKRHLPEKTDIMAVVKADGYGHGAVHVGKEALASGADSLAVALLDEALILRRAGITAPILVLGYTPVESIVTASELEVELTAYSVEWITEANDILQKNDHKPVGIHVKTDTGMGRLGVRTKEDLLAVVGALEECSKLKWTGIFTHFACADEPDTTHVRRQHDLFQSFLQALREANKKLPTVHCCNTAAAIAFPDWGYDTIRLGIGLYGLYPSLYMKERADVILTPALALKTRIAHVKKADEPFTVSYGATHTAQPDEWIATLPIGYADGYSRLLSNRGEVLYNGTRYPIAGRVCMDQIMVSLNSTEAAVNDEVVLYGKQGDEEISLDEIADLLGTINYEVPCMLNYRIPRLYLRDQKVTDVFHPLTMKHSSHENVNI
>NC_012491.1|WP_007721089.1|510212_510512_+|CopG-family-ribbon-helix-helix-protein
MVGGGFVLSKSNTKRIMISLPQHLLQEVDGVIQKEKSNRSEFIRQAMHLYLKERKKRTIRETMQKGYMEMAKINLNMASEAFGAEEEADHTLVRLVSGV
>NC_012491.1|WP_005830205.1|510515_510866_+|type-II-toxin-antitoxin-system-PemK/MazF-family-toxin
MIVKRGDVFFADLSPVVGSEQGGVRPVLVIQNDIGNRFSPTVIVAAITAQIQKAKLPTHVEIDAKTYGFDRDSVILLEQIRTIDKQRLTDKITHLDDEMMDRVNESLQISLGLIDF
>NC_012491.1|WP_012684244.1|511074_511503_+|anti-sigma-regulatory-factor
MVVADYSPETINIEQESDIVTARQVGRNMSKLFGFGTITQSRIATSISELARNIYLYAGAGAIIISPIEREGMIGLQITANDNGPGIPDIRQALDDGYSTSGALGAGLPGVRRMMDEFEIHSTLGEGTRVVVVKWSDQAKEE
>NC_012491.1|WP_012684245.1|511508_512510_+|PP2C-family-protein-serine/threonine-phosphatase
MVTRSFQEEYVKILRDYLSAQGEDQLYGAQQLGKWMLSQDISPEEITDLHAQALEQLGEVPEFVRSSFSILTEVMIEYGNEHRSVNSWRNRHQQMESEIAVAKAMQQSLLPSEVPVYSELEIGVVSIAAKQISGDYYDFIEQSEGRFGVAIADITGKGMPAAMCMSMVKYGLDSLGQMELGPDEMLHHLNRIVGRNIDPSMFVTMMFGSYDSKKHCFRYAMAGHEPGFLYRSAEGKFYDLEGRGNALGLCPNSEYEVQEICLEINDVLILLTDGVTECKNNRYYLQREELVHHLQKEVGESAQKMANGLYNRLLLLSQFNLLDDYTMIVLRRT

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Crispr_ID: NC_012491_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_012491_2

2232716-2232865

Orphan

Consensus_repeat	Method
TGAGAGTCCAAACATGAG	CRT

3 spacers

The CRISPR arrays of NC_012491_2

>merge|NC_012491|2|2232716-2232865|CRT
TGAGAGCCCAAACATGAGGCCAAATGTCAGACCCAATGTGCGACCAAATGAGAGTCCAAACATGCGGCCAAATGTGCGACCGAATGAGAGTCCAAACATGAGACCAAATGTCAGACCGAACGTAAGGCCAAACGAAAGTCCAAACATGAG

>NC_012491|2|1|2232716-2232865|CRT
TGAGAGCCCAAACATGAG	GCCAAATGTCAGACCCAATGTGCGACCAAA
TGAGAGTCCAAACATGCG	GCCAAATGTGCGACCGAA
TGAGAGTCCAAACATGAG	ACCAAATGTCAGACCGAACGTAAGGCCAAA
CGAAAGTCCAAACATGAG

Protein	Signature genes	Signature genes Name	Protein_function
NC_012491.1\|WP_012685849.1\|2237081_2237225_+\|hypothetical-protein	unknown	unknown	unknown
NC_012491.1\|WP_012685852.1\|2239683_2240013_-\|helix-turn-helix-domain-containing-protein	unknown	unknown	gnl\|CDD\|225511
NC_012491.1\|WP_012685837.1\|2225091_2225517_-\|VOC-family-protein	unknown	unknown	gnl\|CDD\|319947
NC_012491.1\|WP_012685853.1\|2240200_2240659_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|380310
NC_012491.1\|WP_007724250.1\|2226506_2226791_+\|4a-hydroxytetrahydrobiopterin-dehydratase	unknown	unknown	gnl\|CDD\|376528
NC_012491.1\|WP_012685850.1\|2237229_2238762_+\|amino-acid-permease	unknown	unknown	gnl\|CDD\|273331
NC_012491.1\|WP_012685855.1\|2242138_2242969_+\|DUF3100-domain-containing-protein	unknown	unknown	gnl\|CDD\|378631
NC_012491.1\|WP_162023108.1\|2238850_2239717_-\|IS3-family-transposase	unknown	unknown	gnl\|CDD\|222853
NC_012491.1\|WP_012685839.1\|2226902_2227223_+\|hypothetical-protein	unknown	unknown	unknown
NC_012491.1\|WP_012685845.1\|2230439_2231954_-\|histidine-ammonia-lyase	unknown	unknown	gnl\|CDD\|236484
NC_012491.1\|WP_041749367.1\|2232283_2232475_-\|hypothetical-protein	unknown	unknown	unknown
NC_012491.1\|WP_012685838.1\|2225692_2226430_+\|methyltransferase-domain-containing-protein	unknown	unknown	gnl\|CDD\|379312
NC_012491.1\|WP_012685840.1\|2227219_2227984_+\|DUF3109-family-protein	unknown	unknown	unknown
NC_012491.1\|WP_012685854.1\|2240935_2242111_+\|amidohydrolase	unknown	unknown	gnl\|CDD\|349941
NC_012491.1\|WP_041749370.1\|2233401_2234328_-\|UV-DNA-damage-repair-endonuclease-UvsE	unknown	unknown	gnl\|CDD\|235029
NC_012491.1\|WP_012685841.1\|2228040_2228550_+\|acyl-CoA-thioesterase	unknown	unknown	gnl\|CDD\|224523
NC_012491.1\|WP_012685844.1\|2229919_2230360_-\|thiol-disulfide-oxidoreductase-DCC-family-protein	unknown	unknown	gnl\|CDD\|225556
NC_012491.1\|WP_012685842.1\|2228625_2229546_+\|aldo/keto-reductase	unknown	unknown	gnl\|CDD\|381312
NC_012491.1\|WP_041749369.1\|2233122_2233443_+\|hypothetical-protein	unknown	unknown	unknown
NC_012491.1\|WP_012685848.1\|2234518_2236936_+\|EAL-domain-containing-protein	unknown	unknown	gnl\|CDD\|236645

Protein	Function_ID	Function_description	E-value
NC_012491.1\|WP_012685853.1\|2240200_2240659_+\|hypothetical-protein	gnl\|CDD\|380310	NF033479, Efa1_rel_toxin, LifA/Efa1-related large cytotoxin. Members of this family are large and almost certainly multifunctional proteins found in various pathogens from genus Chlamydia, about 3000 amino acids in size and related to lymphostatin (Efa1/LifA) from enteropathogenic Escherichia coli. Roles have been suggested for Efa1 (EHEC factor for adherence) in adhesion, so some members have been annotated as adherence proteins rather than cytotoxins.	0.00413683
NC_012491.1\|WP_012685852.1\|2239683_2240013_-\|helix-turn-helix-domain-containing-protein	gnl\|CDD\|225511	COG2963, COG2963, Transposase and inactivated derivatives [DNA replication, recombination, and repair].	6.2734e-06
NC_012491.1\|WP_012685837.1\|2225091_2225517_-\|VOC-family-protein	gnl\|CDD\|319947	cd08359, VOC_like, uncharacterized subfamily of vicinal oxygen chelate (VOC) family. The vicinal oxygen chelate (VOC) superfamily is composed of structurally related proteins with paired beta.alpha.beta.beta.beta motifs that provide a metal coordination environment with two or three open or readily accessible coordination sites to promote direct electrophilic participation of the metal ion in catalysis. VOC domain is found in a variety of structurally related metalloproteins, including the bleomycin resistance protein, glyoxalase I, and type I ring-cleaving dioxygenases. A bound metal ion is required for protein activities for the members of this superfamily. A variety of metal ions have been found in the catalytic centers of these proteins including Fe(II), Mn(II), Zn(II), Ni(II) and Mg(II). The protein superfamily contains members with or without domain swapping. The proteins of this family share three conserved metal binding amino acids with the type I extradiol dioxygenases, which shows no domain swapping.	5.34977e-44
NC_012491.1\|WP_007724250.1\|2226506_2226791_+\|4a-hydroxytetrahydrobiopterin-dehydratase	gnl\|CDD\|376528	pfam01329, Pterin_4a, Pterin 4 alpha carbinolamine dehydratase. Pterin 4 alpha carbinolamine dehydratase is also known as DCoH (dimerization cofactor of hepatocyte nuclear factor 1-alpha).	3.66629e-29
NC_012491.1\|WP_012685850.1\|2237229_2238762_+\|amino-acid-permease	gnl\|CDD\|273331	TIGR00907, Choline_transport_protein, amino acid permease (GABA permease). [Transport and binding proteins, Amino acids, peptides and amines].	6.23772e-84
NC_012491.1\|WP_012685855.1\|2242138_2242969_+\|DUF3100-domain-containing-protein	gnl\|CDD\|378631	pfam11299, DUF3100, Protein of unknown function (DUF3100). Some members in this family of proteins are annotated as membrane proteins however this cannot be confirmed. Currently no function is known.	4.12213e-109
NC_012491.1\|WP_162023108.1\|2238850_2239717_-\|IS3-family-transposase	gnl\|CDD\|222853	PHA02517, PHA02517, putative transposase OrfB; Reviewed.	7.96244e-52
NC_012491.1\|WP_012685845.1\|2230439_2231954_-\|histidine-ammonia-lyase	gnl\|CDD\|236484	PRK09367, PRK09367, histidine ammonia-lyase; Provisional.	0
NC_012491.1\|WP_012685848.1\|2234518_2236936_+\|EAL-domain-containing-protein	gnl\|CDD\|236645	PRK10060, PRK10060, cyclic di-GMP phosphodiesterase.	4.70553e-145
NC_012491.1\|WP_012685838.1\|2225692_2226430_+\|methyltransferase-domain-containing-protein	gnl\|CDD\|379312	pfam13649, Methyltransf_25, Methyltransferase domain. This family appears to be a methyltransferase domain.	1.75309e-22
NC_012491.1\|WP_012685854.1\|2240935_2242111_+\|amidohydrolase	gnl\|CDD\|349941	cd08021, M20_Acy1_YhaA-like, M20 Peptidase aminoacylase 1 subfamily, includes Bacillus subtilis YhaA and Staphylococcus aureus amidohydrolase, SACOL0085. Peptidase M20 family, uncharacterized subfamily of bacterial proteins predicted as putative amidohydrolases or hippurate hydrolases. These are a class of zinc binding homodimeric enzymes involved in hydrolysis of N-acetylated proteins. N-terminal acetylation of proteins is a widespread and highly conserved process that is involved in protection and stability of proteins. Several types of aminoacylases can be distinguished on the basis of substrate specificity. Aminoacylase 1 (ACY1) breaks down cytosolic aliphatic N-acyl-alpha-amino acids (except L-aspartate), especially N-acetyl-methionine and acetyl-glutamate into L-amino acids and an acyl group. However, ACY1 can also catalyze the reverse reaction, the synthesis of acetylated amino acids. ACY1 may also play a role in xenobiotic bioactivation as well as the inter-organ processing of amino acid-conjugated xenobiotic derivatives (S-substituted-N-acetyl-L-cysteine). This family includes Staphylococcus aureus amidohydrolase, SACOL0085, which contains two manganese ions in the active site, and forms a homotetramer with variations in interdomain orientation which possibly plays a role in the regulation of catalytic activity.	0
NC_012491.1\|WP_041749370.1\|2233401_2234328_-\|UV-DNA-damage-repair-endonuclease-UvsE	gnl\|CDD\|235029	PRK02308, uvsE, putative UV damage endonuclease; Provisional.	1.91203e-129
NC_012491.1\|WP_012685841.1\|2228040_2228550_+\|acyl-CoA-thioesterase	gnl\|CDD\|224523	COG1607, COG1607, Acyl-CoA hydrolase [Lipid metabolism].	6.77543e-62
NC_012491.1\|WP_012685844.1\|2229919_2230360_-\|thiol-disulfide-oxidoreductase-DCC-family-protein	gnl\|CDD\|225556	COG3011, COG3011, Predicted thiol-disulfide oxidoreductase [General function prediction only].	7.7555e-45
NC_012491.1\|WP_012685842.1\|2228625_2229546_+\|aldo/keto-reductase	gnl\|CDD\|381312	cd19086, AKR_AKR11C1, AKR11C family of aldo-keto reductase (AKR). Bacillus subtilis uncharacterized oxidoreductase YqkF is a founding member of aldo-keto reductase family 11 member C1 (AKR11C1). It may function as oxidoreductase. This family also includes Bacillus halodurans AKR11C1, an NADPH-dependent 4-hydroxy-2,3-trans-nonenal reductase.	1.30711e-115

>NC_012491.1|WP_041749367.1|2232283_2232475_-|hypothetical-protein
MIGLSDLGFSGEGLIGDGIDGEGNGIAEEGGFGISLGRLGSAVGIGGILRRFSTEFYTSFRMN
>NC_012491.1|WP_012685845.1|2230439_2231954_-|histidine-ammonia-lyase
MNQQVNVVKVDGDQLRIEDVVSIARSATHIQITEEALHRVRASRAMVERMVSQQEVVYGITTGFGKFSDVMIHDEDVSKLQENLIMSHACGMGDPYAVEVVRAMMALRINALAKGYSGIREETLLQLVELCNRGVHPIIPQQGSLGASGDLAPLAHMVLVMLGKGEALVNGKRLSGKEALSEVGLSPIRLEAKEGLALINGTQAMTAQLCLALYDSRVLLESAELIAAMTIEALRGIPKAFDPQLHLIRPHPGQQESAKRLLQHLSGSKRTTGQGELRVQDPYSLRCLPQVHGATRDTLEYVWTTVTRECNSVTDNPILFTETGDVISGGNFHGQPMAFAADFLAIAMAELANISERRTERLVNPQLSGLPGFLTENGGLHSGFMITQYVAASIVSENKVLCHPASVDSIPSSANQEDHVSMGTTSARKLRTIVSNVTKVLAIEYLAAAQAIDFGSGDLGTGTARAYEQLRRVIPRLHEDREMHPDLVKAEELIHQGTLAFVTE
>NC_012491.1|WP_012685844.1|2229919_2230360_-|thiol-disulfide-oxidoreductase-DCC-family-protein
MEGCLMKAGREVDHPAYLLLFDGVCHLCHGAVQFILKRDPHGYIHFASLQSQRAQEILSHYNYQEKDMSSVVFIANGQLYTKSDAILHVGRKLQGGWPLLSNVARLIPRPVRNPIYDWVARNRYRWMGKAEQCLLPTPQIRSRFLD
>NC_012491.1|WP_012685842.1|2228625_2229546_+|aldo/keto-reductase
MKYRRLGKTDLNVSVIGVGTWQFGGEWGLDFSQEAVDQILDKAKDLGINLIDTAECYGDHLSEQLIGGYLKKNRREDWIVATKFGHHFHDKFSRTNHYGAAEVQQQLEKSLQALQTDYIDLYQFHSGPDEAFDNDDLWTYLDKQVQAGTIRHLGLSIAKNDNMHQTSAATSVNAKAIQVVYNRLDQKPEEGVFASCQQQDLGVLARVPLASGYLSGKYKPGSVFGGNDVRHRHDQEHVNKLLLQVEEIKKNEVPEGMDMAQWALAWCLKHPAVTTVIPGSKSPAQVEANAKAADYVSDEHPQAMSK
>NC_012491.1|WP_012685841.1|2228040_2228550_+|acyl-CoA-thioesterase
MNVKTTQESRTIQASLVQPSDTNYHGTIFGGTMMAYIDEVAAIAAMRHSRRPVVTASIDSIDFLAPVKMGHSICLEAFVSSTGKTSMEIFVKVVSENLQTGKRILTATSFLTFVALDEEGNPTEVPAIVPETEEEERLMATADERKKMRKERKGNLQDFVSQLNIEKSI
>NC_012491.1|WP_012685840.1|2227219_2227984_+|DUF3109-family-protein
MKTKRAFRYVGTPDPMSDKEAYHCEKYIKKHKHSLVRAGQYLVDVSALHALFHLDCWNCRTVHRETCCEGGQPYAVEEWQIPIMEGEIPSISAGLQDEAERNHWLLHGVWDRNEPRGTIRMRHGNCLFYQENNGRYGCAIHAYAEQAGREVEPLKPYSCQLYPIDLIDTGEGILLTAVTNETSSFSRWGTDYLEQFYCASPARRKLATHIDDKLFALDGYRPAYKWNLPLLRYILQEEAERIEGILGSSYQLER
>NC_012491.1|WP_012685839.1|2226902_2227223_+|hypothetical-protein
MDIQQHEQLIQVLAEYKNQKASVTFTQWDTDREEEEEVTQFQAQLLETKLTDNEFEEKDLLLVFTTEEGEEMEILMEIPGDEVDLASYEEGHLRIFGTEAEIVLQK
>NC_012491.1|WP_007724250.1|2226506_2226791_+|4a-hydroxytetrahydrobiopterin-dehydratase
MSKLSLEQVKLYLSKVPGWKLVEDRMALSRTYHCRDFSTAISFVNRVAEMLEHDNQHVEIHLAGGTVTFTLATREAKGLTGKDFALAQTISKVS
>NC_012491.1|WP_012685838.1|2225692_2226430_+|methyltransferase-domain-containing-protein
MAEEWFERSFREDYVLVYRHRDDSAADGEIANLLERLPVKDTGRVLDLCCGSGRHSRALARRGYEVVGVDLSPVLLQLAEEQNTYPQLSFARCDMRDIPFREEFDIVVNLFTSFGYFSTDEENANVIRNMAQALKTKGEVVIDFLNAAYVIDNLVPHSTKEVSGMLIKEERWIQDGFVKKRILISDESSNEPREYMEQVRLFSAEQMIAMLTEAGFEKIQVFGNYLFEEYVAHESPRMIFYAVKQ
>NC_012491.1|WP_012685837.1|2225091_2225517_-|VOC-family-protein
MKVNSFYPVILTEQVETSSKFYREHFGFDIVFEADWYVSMQNQSSTPAFELAILNPSHDTIPQGFRKPVEGGLILNFEVDDVDAEYERLIVKAGLPLHLDIRDEDFGQRHFITSDPNGILLDIIKVIPPSEAFADSYVAPV
>NC_012491.1|WP_041749369.1|2233122_2233443_+|hypothetical-protein
MKIAANTWTTANITSIMNEECIIIMTVANYGMTVAVHLGEVHHLHPRVAVAPPPDTIIDIDGIIDEDVGVTADVHFEGYEEGRQLIKRRPFPYSIRKCFNSDSFFL
>NC_012491.1|WP_041749370.1|2233401_2234328_-|UV-DNA-damage-repair-endonuclease-UvsE
MIRMGYACISVKTKNNPNKKTTVAQVNKLDPPARLKKLRQVMQANFFNLMDLLAYNVENQIFLYRLPSEFVPLATHPVAAEWDWAKEFAWDFQKAGNYIRNHGIRLTAHPGHYSILNSDKPSVLEATIADFSYHAKVFDLLGLDDNSVLVTHVGGVYEDKASSLARFASNFEQLPENVKRRVVVENDDTSFTMREVLELCERIGVPMVLDIHHHNCHSDGEDWTEYLPRIIQTWGERTPKMHMSSPKSANDFRAHADDIDPEAFLTFVSALADYNVDIILECKNKDDALLTLRRELKKKGVAVEAFTN
>NC_012491.1|WP_012685848.1|2234518_2236936_+|EAL-domain-containing-protein
MNSLDQSYSMTLFFLSYFISAMASYTALDLGARLHYAKGRGRVFLLCAGAVSMGLGIWAMYFVAMLALHLPIAVEYDHLIVFFSIVLAVLSSALTLWIVSEQSMSKTRVVKGSVVIGTGIAGMHYTGMAAMMMNAVILYDWLWFTVSIFVAILFSMVALILTFQLRSVDPVEGLWRKIFAGLLMGASITGMHYTGMYATTFVAHEHMTIAVIPYDDSGLIATMIGIVSVLILVVTLASVYVDKQFAGKTLRVLESDQRYKSLFEHNYDGVIFYSIDGTQSVMNPAAMRLTKEQSLPLEKLKTMCISTDAELISTHFTNAVQGDARNCDITLTTREGCQLHLNMTHTPVFVDQQITGVFMIVRDITNKKEYEAKINYLAFHDSLTGLPNRRFVEQQLDQVIMEAQKTDQQVYVLFLDLDHFKLVNDSLGHDFGDLLLQEASLRLRECVGKKGTVYRLGGDEFMVILTDVTEREVSSMANEINETIEQAFFIHGHELYITTSIGISRYPEDGQDRSVLMRNADAAMYAAKDKGKNSFHLYVPNLEQAVNDKMNIQNELNRALARQEFLLHYQPQVSAKSGAIVGVEALIRWDHPERGLLLPDQFISVAEETGLIVPIGEWVLRTACKQNKQWQDQGLKPLRVAVNLSARQFLKQDFTQMIAEILHQTRLAPEYLELEITESSMIDVHRATQALKELKQLGVHVAIDDFGTGYSSLYYLKEFPLNRLKIDRSFVRDMIEQPSNQAIVSTIISMAHHLQMHVIAEGVETKEELAFLQEHLCEEVQGYLFSRPLPSEDVAFYLQAQKGVS
>NC_012491.1|WP_012685849.1|2237081_2237225_+|hypothetical-protein
MLALGVILLLFTIGVAIAIGYRANESVRHFDESAHESFIGSQAEREG
>NC_012491.1|WP_012685850.1|2237229_2238762_+|amino-acid-permease
MQQEKEQQLLEDRRDLNKFGYAQELLRDMGGFSNFAISFSIISILTGAVSLYGHGLLYGGSGMMGFGWTLVALFVILIAASMSELASAIPTAGALYHWAAILGSKRWGWYTAWINLIGQIGIVAGIDYSFSLFADPLLASAFGYTSTETTTLILFGITLLLHGTFNHIGIRLVARLNDFSAWYHIGVVVILVGSLVFFSRNDLQPLDYLFQVGQTFSDKPYAIAFLIGLLQAQWTFTGYDASAHTIEETINPRVRAAWGIYTSVAFSFIFGFIMLAFVTLSIKNAAAASEAENAFIYVISEALGGTFGSVVLWLVTFAMWFCGLASITSFSRMLYAFSRDKGMPWSHQWAEISTKYRTPAKAIWLVIILSFALALFDYIVKSINPNTSYTTLAFLTAVSVVGLYVAYGIPLYLKLRAESRGLFQRKHYGPWHLGNWSKPINVLSLIWIVFISIMMVIPPNQTAGYALIAMFLVLLIMDLAYYRKHFRGPQAALGNSEEDIKRQEAKFRDS
>NC_012491.1|WP_162023108.1|2238850_2239717_-|IS3-family-transposase
MQNKHIVVDELRDKRSVQELCACLGISRSGYYAYVKRKDNDPDEHLKRKIRSIYEERDKTVGYRRVQDELYRQYNLKVNHKKVLRLMQELGMQAIIRRKYIHRTSYETAVSDGRITENLLQRNFTAEGPNQKWVTDVTQFRVFDHRIYLSAIKDLWNNEIVAYHLSQRNDNPLVLETFKKAFEKQKDVAGLIVHSDQGYQYTSHAYHDMLPKVGAQISMSRRGNCYDNASMESFFSHLKVEALYPYDIRSIEEAQRRIEEFILFYNEKRAQRKLNKLTPVEYRRQLIA
>NC_012491.1|WP_012685852.1|2239683_2240013_-|helix-turn-helix-domain-containing-protein
MAVKGHKCKHYPETLKVEAVRLHVEEGWSYRKIAEHLGVQDKYRVRTWMRKYRENGDASFKDGRGNPYRVETEQDREIRRLQLEVDVLKKWLQILNREGCKTSTSSLTS
>NC_012491.1|WP_012685853.1|2240200_2240659_+|hypothetical-protein
MKRMRWLLLTMGIVLMAQATSLVPQVSGYDKYVREGNSSNRYEVAGITNAGAFEAFFEKLQEAVKNSDKTEVAKHVRYPLRVNKDGKSQFIRDEQQFLEEYNRIMTEKVKEAFLQQKVTDTFVNDQGVMVGNGEIWLGQFSNRFVVFAINVE
>NC_012491.1|WP_012685854.1|2240935_2242111_+|amidohydrolase
MSLETKKWADEVAEQVISWRRYLHQHPELSFEEEKTSQFIYETLESFGNLELSRPTKTSVVARLIGSQPGKVLGIRADIDALPIHEENDVPYASGKAGVMHACGHDGHTAMLLGAAKILSQYKDQIKGEVRFFFQHAEELPPGGAAEIVRAGAADGLDSIIGIHLASYMPVGKFGVLYGALTSSTDRFDIKIQGKGGHSSQPEASVDPIVIGAQVITGLQQIVSRNVSALDKVVISVTMLNAGTAYNIIPDSMTLTGSTRCFDAQIRQNIPMWIERIVKGITEAHGASYEFTFSHGYTSVVNDKQVTKLMEDTIRERWGEEEIIYIDPLMPGEDFSEYLKKAPGCFIQLGAGNPDKGFTYPHHHPRFDFDEDAMVRGVELFVRAAQKVVME
>NC_012491.1|WP_012685855.1|2242138_2242969_+|DUF3100-domain-containing-protein
MAEARVNEYKLHFLVLILVALTEFIGTKKISIGIGVIALFPMLYALVLGGAISWPKFKFLSEKEMNVAANILGVSFLIFIAKLGANIGPELPKLLGSGVSLVVQEMGHIVGTIALGLPIALWLGLKREAIGATYSLDREPNLAIIVEKFGGNSAEARGALGVYICGTLFGAIYMSILASILGSSGLFHPISLAMGAAVGSGSMMAAATGSLAVIFPEAQKDIAFYSGAANLMMSIVGTYVCIFFSLPVTQKLYAWLEPIIGRKSASSAAEGGRKSA

You can click texts colored in the table to view more detailed information

Click the colored protein region to show detailed information

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity
NC_012491_2	2.3\|2232818\|30\|NC_012491\|CRT	2232818-2232847	30	NC_012491.1	2232986-2233015	2	0.933

1. spacer 2.3|2232818|30|NC_012491|CRT matches to position: 2232986-2233015, mismatch: 2, identity: 0.933

accaaatgtcagaccgaacgtaaggccaaa	CRISPR spacer
accaaatatcagaccgaatgtaaggccaaa	Protospacer
*******.**********.***********

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

616721 : 624591

Geobacillus_virus(16.67%)

transposase

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_041749768.1\|616721_617843_-\|transposase	IS200/IS605 family element transposase accessory protein TnpB	A0A0H3UZC2	Geobacillus_virus	1.1e-130	64.7
WP_012684340.1\|618209_618929_+	phosphoribosylaminoimidazolesuccinocarboxamide synthase	M4SM18	Cyanophage	8.3e-47	43.3
WP_012684341.1\|618921_619170_+	phosphoribosylformylglycinamidine synthase subunit PurS	A0A0E3FJ99	Synechococcus_phage	9.8e-08	36.2
WP_012684342.1\|619174_619867_+	phosphoribosylformylglycinamidine synthase subunit PurQ	NA	NA	NA	NA
WP_012684343.1\|619847_622091_+	phosphoribosylformylglycinamidine synthase subunit PurL	A6N228	Microbacterium_phage	4.5e-176	44.2
WP_012684344.1\|622075_623494_+	amidophosphoribosyltransferase	A0A0M3SGR2	Mollivirus	5.2e-53	34.2
WP_012684345.1\|623550_624591_+	phosphoribosylformylglycinamidine cyclo-ligase	Q58MH8	Prochlorococcus_phage	8.8e-66	44.4

DBSCAN-SWA_2

3012342 : 3133601

Geobacillus_phage(18.75%)

plate,capsid,head,protease,holin,terminase,portal,tail

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_015891181.1\|3012342_3013098_+\|protease	CPBP family intramembrane metalloprotease	NA	NA	NA	NA
WP_015891182.1\|3013335_3016455_+	efflux RND transporter permease subunit	S5VTK5	Leptospira_phage	1.5e-89	26.4
WP_015891183.1\|3016479_3017814_+	efflux RND transporter periplasmic adaptor subunit	NA	NA	NA	NA
WP_015891184.1\|3017835_3018618_+	linear gramicidin aldoreductase LgrE	NA	NA	NA	NA
WP_041749430.1\|3018614_3020159_+	aldo/keto reductase	NA	NA	NA	NA
WP_015891186.1\|3020243_3021008_-	ABC transporter permease	NA	NA	NA	NA
WP_015891187.1\|3021009_3021945_-	ABC transporter ATP-binding protein	A0A2H4PQG7	Staphylococcus_phage	5.2e-25	32.8
WP_015891188.1\|3022438_3029266_+	linear gramicidin non-ribosomal peptide synthetase LgrA	A0A2K9KZV5	Tupanvirus	5.6e-161	26.1
WP_015891189.1\|3029270_3052508_+	linear gramicidin non-ribosomal peptide synthetase LgrB	A0A2K9KZV5	Tupanvirus	9.4e-91	26.1
WP_015891191.1\|3071725_3073069_-	recombinase family protein	A0A1B1P7M0	Bacillus_phage	1.5e-142	55.8
WP_015891192.1\|3073311_3073692_-	helix-turn-helix transcriptional regulator	A0A0C5AN12	Bacteriophage	1.3e-19	47.2
WP_015891193.1\|3073901_3074120_+	helix-turn-helix transcriptional regulator	A0A0C5ABM3	Bacteriophage	2.9e-11	58.3
WP_015891195.1\|3074945_3075188_+	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_015891196.1\|3075224_3075476_+	hypothetical protein	NA	NA	NA	NA
WP_041749433.1\|3075622_3075907_+	hypothetical protein	NA	NA	NA	NA
WP_015891199.1\|3075899_3076181_+	hypothetical protein	NA	NA	NA	NA
WP_041749434.1\|3076177_3076423_+	hypothetical protein	NA	NA	NA	NA
WP_041749435.1\|3077296_3077947_+	ATP-binding protein	A0A059VK34	Pseudomonas_phage	1.5e-07	29.3
WP_015891202.1\|3077939_3079319_+	replicative DNA helicase	A0A1P8VVQ6	Streptococcus_phage	2.4e-103	45.7
WP_050763832.1\|3079460_3080237_+	Rha family transcriptional regulator	A0A2I7SDG8	Paenibacillus_phage	1.5e-38	44.3
WP_015891204.1\|3080259_3080916_+	hypothetical protein	NA	NA	NA	NA
WP_015891205.1\|3080949_3081114_+	hypothetical protein	NA	NA	NA	NA
WP_015891206.1\|3081259_3081982_+	glycosyltransferase family 2 protein	NA	NA	NA	NA
WP_015891207.1\|3082049_3082694_+	hypothetical protein	A0A2H4J4R7	uncultured_Caudovirales_phage	6.5e-11	30.1
WP_155801087.1\|3083250_3083598_+\|terminase	P27 family phage terminase small subunit	Q0H265	Geobacillus_phage	8.6e-18	45.8
WP_041749857.1\|3083590_3085315_+\|terminase	terminase large subunit	Q0H264	Geobacillus_phage	2.4e-257	71.9
WP_015891211.1\|3085320_3086535_+\|portal	phage portal protein	Q0H263	Geobacillus_phage	2.9e-145	63.4
WP_015891212.1\|3086531_3087125_+\|head,protease	HK97 family phage prohead protease	Q0H262	Geobacillus_phage	2.9e-74	73.3
WP_015891213.1\|3087106_3088387_+\|capsid	phage major capsid protein	Q0H261	Geobacillus_phage	4.8e-90	57.4
WP_155801088.1\|3088404_3088545_+	Rho termination factor N-terminal domain-containing protein	NA	NA	NA	NA
WP_015891214.1\|3088535_3088811_+	hypothetical protein	Q0H259	Geobacillus_phage	3.1e-34	78.7
WP_015891215.1\|3088807_3089425_+\|head	phage head closure protein	A0A0S2SXM4	Bacillus_phage	9.0e-10	38.0
WP_015891216.1\|3089421_3089865_+	hypothetical protein	NA	NA	NA	NA
WP_015891217.1\|3089857_3090286_+	HK97 gp10 family phage protein	NA	NA	NA	NA
WP_015891218.1\|3090298_3091357_+\|tail	phage tail sheath subtilisin-like domain-containing protein	A0A0A8WJL8	Clostridium_phage	3.6e-75	47.5
WP_015891219.1\|3091376_3091811_+\|tail	phage tail tube protein	A0A0K2SUB8	Clostridium_phage	5.9e-16	37.9
WP_015891220.1\|3091835_3092219_+	hypothetical protein	NA	NA	NA	NA
WP_155801090.1\|3092520_3094230_+	tape measure protein	M1HMP3	Bacillus_virus	3.4e-30	38.0
WP_041749437.1\|3094241_3094664_+	hypothetical protein	NA	NA	NA	NA
WP_015891223.1\|3094668_3095685_+	hypothetical protein	NA	NA	NA	NA
WP_041749438.1\|3095696_3096161_+	DUF2577 domain-containing protein	NA	NA	NA	NA
WP_015891225.1\|3096157_3096595_+	DUF2634 domain-containing protein	NA	NA	NA	NA
WP_041749861.1\|3096621_3097653_+\|plate	baseplate J/gp47 family protein	S6AVU3	Thermus_phage	5.5e-44	36.8
WP_015891227.1\|3097645_3098248_+	DUF2313 domain-containing protein	NA	NA	NA	NA
WP_015891228.1\|3098260_3098620_+	hypothetical protein	F8WQ03	Bacillus_phage	1.5e-12	42.6
WP_015891229.1\|3098624_3098945_+	hypothetical protein	NA	NA	NA	NA
WP_015891230.1\|3098946_3099501_+	hypothetical protein	NA	NA	NA	NA
WP_015891231.1\|3099517_3101191_+	hypothetical protein	NA	NA	NA	NA
WP_015891232.1\|3101187_3101364_+	hypothetical protein	NA	NA	NA	NA
WP_015891233.1\|3101350_3102526_+	polysaccharide deacetylase family protein	G3MB53	Bacillus_virus	2.0e-58	35.6
WP_015891234.1\|3102603_3102861_+	hemolysin XhlA family protein	D2J075	Enterococcus_phage	1.2e-08	39.5
WP_015891235.1\|3102861_3103149_+\|holin	phage holin family protein	A0A2H4JAH4	uncultured_Caudovirales_phage	6.3e-06	40.7
WP_015891236.1\|3103148_3103832_+	glycoside hydrolase family 73 protein	A0A0K2CP65	Brevibacillus_phage	2.8e-52	70.4
WP_015891237.1\|3104033_3105029_+	hypothetical protein	A0A0K2CYL7	Paenibacillus_phage	1.4e-41	35.2
WP_081437243.1\|3105049_3105457_+	hypothetical protein	R9W0N7	Paenibacillus_phage	2.1e-15	37.4
WP_155801091.1\|3105434_3105851_+	hypothetical protein	NA	NA	NA	NA
WP_155801092.1\|3106022_3106169_+	hypothetical protein	NA	NA	NA	NA
WP_155801093.1\|3106165_3106366_+	hypothetical protein	NA	NA	NA	NA
WP_015891239.1\|3106501_3107341_+	hypothetical protein	NA	NA	NA	NA
WP_015891241.1\|3108107_3108575_-	hypothetical protein	NA	NA	NA	NA
WP_015891242.1\|3108599_3109013_-	hypothetical protein	NA	NA	NA	NA
WP_015891243.1\|3109140_3109452_-	aspartyl-phosphate phosphatase Spo0E family protein	NA	NA	NA	NA
WP_015891244.1\|3109707_3111075_-	helix-turn-helix transcriptional regulator	A0A0K2CP77	Brevibacillus_phage	3.1e-95	42.8
WP_015891246.1\|3115517_3130775_+	linear gramicidin non-ribosomal peptide synthetase LgrD	A0A2K9KZV5	Tupanvirus	3.3e-193	29.5
WP_007729128.1\|3130879_3131074_+	PLDc N-terminal domain-containing protein	NA	NA	NA	NA
WP_015891247.1\|3131106_3132024_+	ABC transporter ATP-binding protein	A0A2H4PQG7	Staphylococcus_phage	1.2e-26	34.2
WP_015891248.1\|3132023_3132809_+	ABC transporter permease	NA	NA	NA	NA
WP_015891249.1\|3132824_3133601_+\|protease	CPBP family intramembrane metalloprotease	NA	NA	NA	NA

DBSCAN-SWA_3

3694048 : 3743737

Bacillus_phage(30.43%)

plate,capsid,protease,tRNA,holin,terminase,portal,tail

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_172801914.1\|3694048_3695443_-\|protease	ATP-dependent protease ATPase subunit HslU	A0A191ZC11	Erwinia_phage	9.1e-42	26.7
WP_015891764.1\|3695466_3696009_-\|protease	ATP-dependent protease subunit HslV	NA	NA	NA	NA
WP_015891765.1\|3696024_3696969_-	tyrosine recombinase XerC	A0A0K2CP59	Brevibacillus_phage	9.5e-35	31.9
WP_015891766.1\|3697030_3698344_-\|tRNA	FADH(2)-oxidizing methylenetetrahydrofolate--tRNA-(uracil(54)-C(5))- methyltransferase TrmFO	NA	NA	NA	NA
WP_015891767.1\|3698383_3700462_-	type I DNA topoisomerase	A0A1V0SB35	Catovirus	7.3e-104	36.2
WP_041749491.1\|3700568_3701687_-	DNA-protecting protein DprA	NA	NA	NA	NA
WP_015891769.1\|3701810_3702713_-	succinate--CoA ligase subunit alpha	NA	NA	NA	NA
WP_007719385.1\|3702757_3703918_-	ADP-forming succinate--CoA ligase subunit beta	NA	NA	NA	NA
WP_041749492.1\|3704104_3705160_-	hypothetical protein	NA	NA	NA	NA
WP_015891771.1\|3705196_3706090_-	ATP-binding protein	NA	NA	NA	NA
WP_015891772.1\|3706174_3706513_-	SCP2 sterol-binding domain-containing protein	NA	NA	NA	NA
WP_015891773.1\|3706584_3706899_-	YbjQ family protein	NA	NA	NA	NA
WP_015891774.1\|3707021_3707834_-	GGDEF domain-containing protein	NA	NA	NA	NA
WP_015891775.1\|3707830_3708187_-	hypothetical protein	NA	NA	NA	NA
WP_015891776.1\|3708216_3708939_-	EAL domain-containing protein	NA	NA	NA	NA
WP_015891778.1\|3709430_3709739_+\|protease	protease inhibitor I42 family protein	NA	NA	NA	NA
WP_015891781.1\|3711051_3711324_+	helix-turn-helix transcriptional regulator	A0A0K2CYN0	Paenibacillus_phage	2.1e-11	40.5
WP_015891782.1\|3711594_3712092_+	hypothetical protein	NA	NA	NA	NA
WP_041749493.1\|3712314_3713292_-	thermonuclease family protein	A0A1P8CWK6	Bacillus_phage	7.3e-38	51.1
WP_015891784.1\|3713326_3714043_-	restriction endonuclease	NA	NA	NA	NA
WP_015891785.1\|3714574_3714847_-	YolD-like family protein	NA	NA	NA	NA
WP_015891786.1\|3715292_3715985_-	hypothetical protein	NA	NA	NA	NA
WP_041749496.1\|3716106_3716328_+	hypothetical protein	NA	NA	NA	NA
WP_015891787.1\|3716616_3716754_-	hypothetical protein	NA	NA	NA	NA
WP_015891788.1\|3716758_3717571_-	N-acetylmuramoyl-L-alanine amidase	A0A0M4S688	Bacillus_phage	2.6e-33	47.9
WP_015891789.1\|3717573_3718032_-\|holin	phage holin family protein	Q0H258	Geobacillus_phage	2.8e-08	30.3
WP_015891790.1\|3718151_3718301_-	hypothetical protein	NA	NA	NA	NA
WP_015891791.1\|3718297_3718531_-	hypothetical protein	NA	NA	NA	NA
WP_015891792.1\|3718543_3719233_-	hypothetical protein	NA	NA	NA	NA
WP_015891793.1\|3719247_3720369_-	hypothetical protein	F8WQ05	Bacillus_phage	6.0e-52	31.7
WP_015891794.1\|3720371_3722444_-	DUF4815 domain-containing protein	F8WQ05	Bacillus_phage	1.2e-133	36.7
WP_155801099.1\|3722455_3722977_-	hypothetical protein	A0A0A0RML6	Bacillus_phage	5.1e-14	31.8
WP_015891796.1\|3722989_3723715_-	hypothetical protein	NA	NA	NA	NA
WP_015891797.1\|3723711_3724458_-\|plate	baseplate J/gp47 family protein	S6AVU3	Thermus_phage	2.2e-10	45.8
WP_015891798.1\|3724450_3724888_-	DUF2634 domain-containing protein	A0A0N7ACH4	Bacillus_phage	8.9e-12	34.8
WP_015891799.1\|3724884_3725316_-	DUF2577 domain-containing protein	A0A2H4IZR8	uncultured_Caudovirales_phage	8.2e-18	47.2
WP_015891800.1\|3725312_3726305_-	hypothetical protein	NA	NA	NA	NA
WP_015891801.1\|3726332_3726893_-	hypothetical protein	A0A2H4J2N2	uncultured_Caudovirales_phage	2.5e-22	37.9
WP_015891802.1\|3727374_3729729_-\|tail	phage tail tape measure protein	A0A097I4X9	Vibrio_phage	4.5e-17	24.5
WP_015891803.1\|3729732_3729876_-	hypothetical protein	NA	NA	NA	NA
WP_015891804.1\|3729926_3730358_-	hypothetical protein	NA	NA	NA	NA
WP_015891805.1\|3730394_3730796_-\|tail	phage tail tube protein	NA	NA	NA	NA
WP_015891806.1\|3730807_3732223_-\|tail	phage tail protein	A0A0A8WI77	Clostridium_phage	3.2e-34	30.6
WP_015891807.1\|3732223_3732409_-	hypothetical protein	NA	NA	NA	NA
WP_041749498.1\|3732371_3732866_-	hypothetical protein	NA	NA	NA	NA
WP_015891808.1\|3732858_3733353_-	HK97 gp10 family phage protein	NA	NA	NA	NA
WP_015891809.1\|3733352_3733739_-	hypothetical protein	NA	NA	NA	NA
WP_015891810.1\|3733726_3734044_-	DNA-packaging protein	NA	NA	NA	NA
WP_015891811.1\|3734024_3734198_-	hypothetical protein	NA	NA	NA	NA
WP_041749882.1\|3734220_3735186_-\|capsid	phage major capsid protein	A0A2H4JCG0	uncultured_Caudovirales_phage	2.0e-51	40.2
WP_015891813.1\|3735211_3735904_-	hypothetical protein	NA	NA	NA	NA
WP_015891814.1\|3735900_3736113_-\|protease	ribosomal-processing cysteine protease Prp	NA	NA	NA	NA
WP_015891815.1\|3736166_3737075_-\|capsid	minor capsid protein	A0A2H4J4W7	uncultured_Caudovirales_phage	5.1e-09	25.8
WP_015891816.1\|3737071_3738619_-\|portal	phage portal protein	I1TJV4	Clostridium_phage	8.3e-28	23.6
WP_015891817.1\|3738643_3740053_-\|terminase	terminase	G1JWB7	Mycobacterium_phage	9.2e-34	26.2
WP_015891818.1\|3740033_3740657_-	hypothetical protein	A0A1B1P7C9	Bacillus_phage	2.8e-27	42.4
WP_015891819.1\|3740738_3741152_-	hypothetical protein	NA	NA	NA	NA
WP_015891820.1\|3741270_3742002_-	DUF4145 domain-containing protein	NA	NA	NA	NA
WP_015891821.1\|3742066_3742300_-	hypothetical protein	A8ATN7	Listeria_phage	1.9e-05	35.1
WP_015891822.1\|3742438_3743737_-	DNA modification methylase	A0A2I4R670	Erysipelothrix_phage	1.5e-91	45.3

DBSCAN-SWA_4

3751850 : 3758815

Bacillus_phage(28.57%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_015891837.1\|3751850_3752666_-	DNA adenine methylase	A0A2H4JFS7	uncultured_Caudovirales_phage	3.5e-62	50.4
WP_015891838.1\|3752779_3753862_+	DUF3578 domain-containing protein	NA	NA	NA	NA
WP_041749502.1\|3753998_3754217_+	hypothetical protein	NA	NA	NA	NA
WP_015891839.1\|3754259_3755252_-	DnaD domain protein	U6C6J3	Ralstonia_phage	9.4e-33	61.1
WP_155801126.1\|3755271_3755628_-	HNH endonuclease	S5MCD9	Brevibacillus_phage	1.2e-35	60.7
WP_015891841.1\|3755796_3756741_-	recombinase RecT	Q38143	Bacillus_phage	9.8e-48	37.3
WP_015891842.1\|3756740_3757610_-	YqaJ viral recombinase family protein	S6C475	Thermus_phage	1.2e-68	48.7
WP_015891843.1\|3757728_3758436_-	hypothetical protein	A0A0S2MVI5	Bacillus_phage	1.6e-82	62.6
WP_015891844.1\|3758443_3758815_-	hypothetical protein	A0A1L2JY32	Aeribacillus_phage	1.3e-35	65.2

DBSCAN-SWA_5

3938792 : 3947045

Cyanophage(16.67%)

tail

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_015892022.1\|3938792_3940292_-	glucose-6-phosphate dehydrogenase	M4SP85	Cyanophage	2.6e-79	37.3
WP_015892023.1\|3940389_3941010_-	arylformamidase	NA	NA	NA	NA
WP_015892024.1\|3941147_3942326_-	AAA family ATPase	R4TQL5	Phaeocystis_globosa_virus	5.7e-13	24.8
WP_015892025.1\|3942510_3943035_-\|tail	phage tail protein	A0A222ZG41	Arthrobacter_phage	3.6e-15	33.7
WP_015892026.1\|3943050_3943560_-\|tail	phage tail protein	A0A0E3HIJ7	Synechococcus_phage	5.9e-07	35.8
WP_015892027.1\|3943587_3944103_-\|tail	phage tail protein	G0YKE5	Acinetobacter_phage	1.1e-05	47.4
WP_015892028.1\|3944157_3944634_-	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_015892029.1\|3944865_3945183_+	winged helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_015892030.1\|3945280_3946378_+	saccharopine dehydrogenase	NA	NA	NA	NA
WP_041749519.1\|3946406_3947045_-	orotate phosphoribosyltransferase	S4W4D9	Pandoravirus	3.5e-25	34.1

DBSCAN-SWA_6

4412606 : 4455782

Bacillus_phage(42.86%)

bacteriocin,plate,tail

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_007721249.1\|4412606_4413455_+\|bacteriocin	bacteriocin family protein	NA	NA	NA	NA
WP_015892427.1\|4413598_4414417_+	alpha/beta hydrolase	NA	NA	NA	NA
WP_015892428.1\|4414471_4415680_-	PLP-dependent aminotransferase family protein	NA	NA	NA	NA
WP_015892429.1\|4415875_4416346_-	hypothetical protein	NA	NA	NA	NA
WP_015892430.1\|4416500_4417682_-	pyridoxal phosphate-dependent aminotransferase	NA	NA	NA	NA
WP_015892431.1\|4417941_4419198_-	MFS transporter	A0A2H4PQR6	Staphylococcus_phage	1.1e-59	35.1
WP_015892432.1\|4419201_4419684_-	cyclic pyranopterin monophosphate synthase MoaC	NA	NA	NA	NA
WP_015892433.1\|4419856_4420396_+	methylated-DNA--[protein]-cysteine S-methyltransferase	A0A2K9V7K0	Bandra_megavirus	3.3e-16	44.4
WP_015892434.1\|4420388_4421102_+	2OG-Fe(II) oxygenase	NA	NA	NA	NA
WP_015892435.1\|4421114_4421933_+	radical SAM protein	NA	NA	NA	NA
WP_015892436.1\|4422036_4422744_+	molybdenum cofactor biosynthesis protein MoaE	NA	NA	NA	NA
WP_015892437.1\|4422748_4423774_+	ThiF family adenylyltransferase	A0A1V0SAV8	Catovirus	3.6e-11	29.7
WP_015892438.1\|4423837_4424902_-	HAMP domain-containing sensor histidine kinase	W8CYF6	Bacillus_phage	2.9e-80	47.7
WP_015892439.1\|4424898_4425573_-	response regulator transcription factor	W8CYM9	Bacillus_phage	3.8e-86	69.9
WP_015892440.1\|4425576_4427334_-	ABC transporter ATP-binding protein	W8CYL7	Bacillus_phage	5.0e-178	63.1
WP_015892441.1\|4427621_4430351_+	aconitate hydratase AcnA	NA	NA	NA	NA
WP_015892442.1\|4430527_4431709_+	alanine racemase	NA	NA	NA	NA
WP_015892443.1\|4431772_4432096_+	DUF3892 domain-containing protein	NA	NA	NA	NA
WP_015892444.1\|4432181_4432685_-	DUF4188 domain-containing protein	NA	NA	NA	NA
WP_015892445.1\|4432694_4433327_-	TetR/AcrR family transcriptional regulator	NA	NA	NA	NA
WP_041749553.1\|4433739_4434156_+	MarR family transcriptional regulator	NA	NA	NA	NA
WP_041749908.1\|4434178_4435468_+	MFS transporter	NA	NA	NA	NA
WP_015892448.1\|4435545_4436292_-	IclR family transcriptional regulator	NA	NA	NA	NA
WP_015892450.1\|4437300_4438125_-	aldo/keto reductase	A0A2H4PQR8	Staphylococcus_phage	1.1e-66	49.4
WP_015892451.1\|4438203_4439841_-	hypothetical protein	NA	NA	NA	NA
WP_041749554.1\|4439877_4441986_-\|tail	phage tail protein	NA	NA	NA	NA
WP_015892453.1\|4442010_4444254_-\|plate	putative baseplate assembly protein	NA	NA	NA	NA
WP_041749555.1\|4444271_4447346_-\|plate	putative baseplate assembly protein	NA	NA	NA	NA
WP_015892455.1\|4447392_4447794_-	GPW/gp25 family protein	NA	NA	NA	NA
WP_015892456.1\|4447811_4448537_-	hypothetical protein	NA	NA	NA	NA
WP_015892457.1\|4448533_4449649_-	phage late control D family protein	NA	NA	NA	NA
WP_015892458.1\|4449656_4450292_-	hypothetical protein	NA	NA	NA	NA
WP_015892459.1\|4450349_4454192_-	hypothetical protein	NA	NA	NA	NA
WP_015892460.1\|4454225_4454690_-\|tail	phage tail protein	NA	NA	NA	NA
WP_015892461.1\|4454695_4454887_-	hypothetical protein	NA	NA	NA	NA
WP_007721338.1\|4454883_4455261_-	hypothetical protein	NA	NA	NA	NA
WP_007721341.1\|4455350_4455782_-\|tail	phage tail protein	NA	NA	NA	NA

DBSCAN-SWA_7

5664838 : 5692356

Geobacillus_phage(28.57%)

plate,capsid,head,protease,holin,terminase,portal,tail

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_081437243.1\|5664838_5665246_-	hypothetical protein	R9W0N7	Paenibacillus_phage	2.1e-15	37.4
WP_015891237.1\|5665266_5666262_-	hypothetical protein	A0A0K2CYL7	Paenibacillus_phage	1.4e-41	35.2
WP_015891236.1\|5666463_5667147_-	glycoside hydrolase family 73 protein	A0A0K2CP65	Brevibacillus_phage	2.8e-52	70.4
WP_015891235.1\|5667146_5667434_-\|holin	phage holin family protein	A0A2H4JAH4	uncultured_Caudovirales_phage	6.3e-06	40.7
WP_015891234.1\|5667434_5667692_-	hemolysin XhlA family protein	D2J075	Enterococcus_phage	1.2e-08	39.5
WP_015891233.1\|5667769_5668945_-	polysaccharide deacetylase family protein	G3MB53	Bacillus_virus	2.0e-58	35.6
WP_015891232.1\|5668931_5669108_-	hypothetical protein	NA	NA	NA	NA
WP_015891231.1\|5669104_5670778_-	hypothetical protein	NA	NA	NA	NA
WP_015891230.1\|5670794_5671349_-	hypothetical protein	NA	NA	NA	NA
WP_015891229.1\|5671350_5671671_-	hypothetical protein	NA	NA	NA	NA
WP_015891228.1\|5671675_5672035_-	hypothetical protein	F8WQ03	Bacillus_phage	1.5e-12	42.6
WP_015891227.1\|5672047_5672650_-	DUF2313 domain-containing protein	NA	NA	NA	NA
WP_041749861.1\|5672642_5673674_-\|plate	baseplate J/gp47 family protein	S6AVU3	Thermus_phage	5.5e-44	36.8
WP_015891225.1\|5673700_5674138_-	DUF2634 domain-containing protein	NA	NA	NA	NA
WP_041749438.1\|5674134_5674599_-	DUF2577 domain-containing protein	NA	NA	NA	NA
WP_015891223.1\|5674610_5675627_-	hypothetical protein	NA	NA	NA	NA
WP_041749437.1\|5675631_5676054_-	hypothetical protein	NA	NA	NA	NA
WP_155801090.1\|5676065_5677775_-	tape measure protein	M1HMP3	Bacillus_virus	3.4e-30	38.0
WP_015891220.1\|5678076_5678460_-	hypothetical protein	NA	NA	NA	NA
WP_015891219.1\|5678484_5678919_-\|tail	phage tail tube protein	A0A0K2SUB8	Clostridium_phage	5.9e-16	37.9
WP_015891218.1\|5678938_5679997_-\|tail	phage tail sheath subtilisin-like domain-containing protein	A0A0A8WJL8	Clostridium_phage	3.6e-75	47.5
WP_015891217.1\|5680009_5680438_-	HK97 gp10 family phage protein	NA	NA	NA	NA
WP_015891216.1\|5680430_5680874_-	hypothetical protein	NA	NA	NA	NA
WP_015891215.1\|5680870_5681488_-\|head	phage head closure protein	A0A0S2SXM4	Bacillus_phage	9.0e-10	38.0
WP_015891214.1\|5681484_5681760_-	hypothetical protein	Q0H259	Geobacillus_phage	3.1e-34	78.7
WP_155801088.1\|5681750_5681891_-	Rho termination factor N-terminal domain-containing protein	NA	NA	NA	NA
WP_015891213.1\|5681908_5683189_-\|capsid	phage major capsid protein	Q0H261	Geobacillus_phage	4.8e-90	57.4
WP_015891212.1\|5683170_5683764_-\|head,protease	HK97 family phage prohead protease	Q0H262	Geobacillus_phage	2.9e-74	73.3
WP_015891211.1\|5683760_5684975_-\|portal	phage portal protein	Q0H263	Geobacillus_phage	2.9e-145	63.4
WP_041749857.1\|5684980_5686705_-\|terminase	terminase large subunit	Q0H264	Geobacillus_phage	2.4e-257	71.9
WP_155801087.1\|5686697_5687045_-\|terminase	P27 family phage terminase small subunit	Q0H265	Geobacillus_phage	8.6e-18	45.8
WP_015891207.1\|5687601_5688246_-	hypothetical protein	A0A2H4J4R7	uncultured_Caudovirales_phage	6.5e-11	30.1
WP_015891206.1\|5688313_5689036_-	glycosyltransferase family 2 protein	NA	NA	NA	NA
WP_015891205.1\|5689181_5689346_-	hypothetical protein	NA	NA	NA	NA
WP_015891204.1\|5689379_5690036_-	hypothetical protein	NA	NA	NA	NA
WP_050763832.1\|5690058_5690835_-	Rha family transcriptional regulator	A0A2I7SDG8	Paenibacillus_phage	1.5e-38	44.3
WP_015891202.1\|5690976_5692356_-	replicative DNA helicase	A0A1P8VVQ6	Streptococcus_phage	2.4e-103	45.7

DBSCAN-SWA_8

6213462 : 6222827

Caulobacter_phage(42.86%)

protease

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_015894022.1\|6213462_6213918_+	tellurite resistance TerB family protein	Q1MVI3	Enterobacteria_phage	9.0e-15	32.1
WP_015894023.1\|6214001_6215207_+	HpcH/HpaI aldolase/citrate lyase family protein	NA	NA	NA	NA
WP_041749736.1\|6215271_6216519_+	phosphoribosyltransferase family protein	A0A172Q0Y1	Acinetobacter_phage	3.3e-11	28.4
WP_015894025.1\|6216540_6217686_+\|protease	cysteine protease StiP family protein	A0A172Q0S8	Acinetobacter_phage	2.0e-39	33.1
WP_015894026.1\|6217682_6218498_+	hypothetical protein	NA	NA	NA	NA
WP_015894027.1\|6218688_6219294_+	TerD family protein	K4JRX3	Caulobacter_phage	1.4e-23	31.5
WP_015894028.1\|6219351_6219933_+	TerD family protein	K4JRX3	Caulobacter_phage	1.7e-26	40.0
WP_015894029.1\|6219969_6220554_+	TerD family protein	K4JRX3	Caulobacter_phage	1.4e-28	37.9
WP_015894030.1\|6220683_6221919_+	TerD family protein	NA	NA	NA	NA
WP_015894031.1\|6221936_6222827_+	DUF475 domain-containing protein	S5MAL1	Bacillus_phage	2.3e-62	49.6

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. NC_012491

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection