CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NC_013654	Escherichia coli SE15, complete genome	2 crisprs	DinG,cas3,RT,DEDDh,c2c9_V-U4,csa3	0	1	4	0
NC_013655	Escherichia coli SE15 plasmid pECSF1, complete sequence	0 crisprs	RT	0	0	1	0

Results visualization

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CRISPR-Cas detection and classification

Crispr_ID: NC_013654_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_013654_1

728607-728748

Orphan

Consensus_repeat	Method
GCCGGATGCGGCGTGAACGCCTTATCCGGCCTACAAAAGAAATGCAG	CRISPRCasFinder

1 spacers

The CRISPR arrays of NC_013654_1

>merge|NC_013654|1|728607-728748|CRISPRCasFinder
GCCGGATGCGGCGTGAACGCCTTATCCGGCCTACAAAAGAAATGCAGAAACCGTAGGCCTGATAAGACGCGCAAGCGTCGCATCAGGCAAACAGCGCCGGATGCGGCGTGAATGCCTTATCCGGCCTACAAAAGAAATGCAG

>NC_013654|1|1|728607-728748|CRISPRCasFinder
GCCGGATGCGGCGTGAACGCCTTATCCGGCCTACAAAAGAAATGCAG	AAACCGTAGGCCTGATAAGACGCGCAAGCGTCGCATCAGGCAAACAGC
GCCGGATGCGGCGTGAATGCCTTATCCGGCCTACAAAAGAAATGCAG

Protein	Signature genes	Signature genes Name	Protein_function
NC_013654.1\|WP_000775540.1\|726061_727828_+\|succinate-dehydrogenase-flavoprotein-subunit	unknown	unknown	gnl\|CDD\|181594
NC_013654.1\|WP_001235263.1\|727843_728560_+\|succinate-dehydrogenase-iron-sulfur-subunit-SdhB	unknown	unknown	gnl\|CDD\|235652
NC_013654.1\|WP_000725054.1\|740843_742037_+\|tetratricopeptide-repeat-protein	unknown	unknown	gnl\|CDD\|276809
NC_013654.1\|WP_000568275.1\|745163_746303_+\|cytochrome-d-ubiquinol-oxidase-subunit-II	unknown	unknown	gnl\|CDD\|184965
NC_013654.1\|WP_000509910.1\|735187_735910_-\|mannosyl-D-glycerate-transport/metabolism-system-transcriptional-repressor-MngR	unknown	unknown	gnl\|CDD\|182065
NC_013654.1\|WP_001181475.1\|728921_731723_+\|2-oxoglutarate-dehydrogenase-E1-component	unknown	unknown	gnl\|CDD\|236499
NC_013654.1\|WP_001048602.1\|733048_734215_+\|ADP-forming-succinate--CoA-ligase-subunit-beta	unknown	unknown	gnl\|CDD\|234813
NC_013654.1\|WP_000399432.1\|719269_720466_+\|UxaA-family-hydrolase	unknown	unknown	gnl\|CDD\|377287
NC_013654.1\|WP_000099866.1\|731737_732955_+\|2-oxoglutarate-dehydrogenase-complex-dihydrolipoyllysine-residue-succinyltransferase	unknown	unknown	gnl\|CDD\|235571
NC_013654.1\|WP_001054880.1\|736078_737995_+\|PTS-2-O-a-mannosyl-D-glycerate-transporter-subunit-IIABC	unknown	unknown	gnl\|CDD\|182066
NC_013654.1\|WP_000254365.1\|725714_726062_+\|succinate-dehydrogenase-membrane-anchor-subunit	unknown	unknown	gnl\|CDD\|181901
NC_013654.1\|WP_000263355.1\|725316_725721_+\|succinate-dehydrogenase-cytochrome-b556-subunit	unknown	unknown	gnl\|CDD\|181900
NC_013654.1\|WP_000735581.1\|720493_721462_+\|TRAP-transporter-substrate-binding-protein-DctP	unknown	unknown	gnl\|CDD\|270387
NC_013654.1\|WP_000785832.1\|723339_724623_-\|citrate-(Si)-synthase	unknown	unknown	gnl\|CDD\|180164
NC_013654.1\|WP_000126143.1\|721982_723293_+\|TRAP-transporter-large-permease	unknown	unknown	gnl\|CDD\|224509
NC_013654.1\|WP_000025458.1\|734214_735084_+\|succinate--CoA-ligase-subunit-alpha	unknown	unknown	gnl\|CDD\|180194
NC_013654.1\|WP_001237779.1\|721521_721983_+\|TRAP-transporter-small-permease	unknown	unknown	gnl\|CDD\|225632
NC_013654.1\|WP_000884361.1\|743579_745148_+\|cytochrome-ubiquinol-oxidase-subunit-I	unknown	unknown	gnl\|CDD\|185052
NC_013654.1\|WP_001305582.1\|724828_724936_-\|hypothetical-protein	unknown	unknown	unknown
NC_013654.1\|WP_000648958.1\|738012_740646_+\|mannosylglycerate-hydrolase	unknown	unknown	gnl\|CDD\|182093

Protein	Function_ID	Function_description	E-value
NC_013654.1\|WP_000775540.1\|726061_727828_+\|succinate-dehydrogenase-flavoprotein-subunit	gnl\|CDD\|181594	PRK08958, sdhA, succinate dehydrogenase flavoprotein subunit; Reviewed.	0
NC_013654.1\|WP_001235263.1\|727843_728560_+\|succinate-dehydrogenase-iron-sulfur-subunit-SdhB	gnl\|CDD\|235652	PRK05950, sdhB, succinate dehydrogenase iron-sulfur subunit; Reviewed.	3.48257e-167
NC_013654.1\|WP_000568275.1\|745163_746303_+\|cytochrome-d-ubiquinol-oxidase-subunit-II	gnl\|CDD\|184965	PRK15003, PRK15003, cytochrome d ubiquinol oxidase subunit II.	0
NC_013654.1\|WP_000509910.1\|735187_735910_-\|mannosyl-D-glycerate-transport/metabolism-system-transcriptional-repressor-MngR	gnl\|CDD\|182065	PRK09764, PRK09764, GntR family transcriptional regulator.	1.54929e-163
NC_013654.1\|WP_001181475.1\|728921_731723_+\|2-oxoglutarate-dehydrogenase-E1-component	gnl\|CDD\|236499	PRK09404, sucA, 2-oxoglutarate dehydrogenase E1 component; Reviewed.	0
NC_013654.1\|WP_001048602.1\|733048_734215_+\|ADP-forming-succinate--CoA-ligase-subunit-beta	gnl\|CDD\|234813	PRK00696, sucC, ADP-forming succinate--CoA ligase subunit beta.	0
NC_013654.1\|WP_000399432.1\|719269_720466_+\|UxaA-family-hydrolase	gnl\|CDD\|377287	pfam04295, GD_AH_C, D-galactarate dehydratase / Altronate hydrolase, C-terminus. Family members include the C termini of D-galactarate dehydratase (EC:4.2.1.42) which is thought to catalyze the reaction D-galactarate = 5-keto-4-deoxy-D-glucarate + H2O, and altronate hydrolase (altronic acid hydratase, EC:4.2.1.7), which catalyzes D-altronate = 2-keto-2-deoxygluconate + H2O. As purified, both enzymes are catalytically inactive in the absence of added Fe2+, Mn2+, and beta-mercaptoethanol. Synergistic activation of altronate hydrolase activity is seen in the presence of both iron and manganese ions, suggesting that the enzyme may have two ion binding sites. Mn2+ appears to be part of the enzyme active centre, but the function of the single bound Fe2+ ion is unknown. The hydratase has no Fe-S core.	5.6924e-134
NC_013654.1\|WP_000099866.1\|731737_732955_+\|2-oxoglutarate-dehydrogenase-complex-dihydrolipoyllysine-residue-succinyltransferase	gnl\|CDD\|235571	PRK05704, PRK05704, 2-oxoglutarate dehydrogenase complex dihydrolipoyllysine-residue succinyltransferase.	0
NC_013654.1\|WP_001054880.1\|736078_737995_+\|PTS-2-O-a-mannosyl-D-glycerate-transporter-subunit-IIABC	gnl\|CDD\|182066	PRK09765, PRK09765, PTS system 2-O-a-mannosyl-D-glycerate specific transporter subunit IIABC; Provisional.	0
NC_013654.1\|WP_000254365.1\|725714_726062_+\|succinate-dehydrogenase-membrane-anchor-subunit	gnl\|CDD\|181901	PRK09488, sdhD, succinate dehydrogenase membrane anchor subunit.	5.54037e-58
NC_013654.1\|WP_000263355.1\|725316_725721_+\|succinate-dehydrogenase-cytochrome-b556-subunit	gnl\|CDD\|181900	PRK09487, sdhC, succinate dehydrogenase cytochrome b556 subunit.	3.50714e-82
NC_013654.1\|WP_000735581.1\|720493_721462_+\|TRAP-transporter-substrate-binding-protein-DctP	gnl\|CDD\|270387	cd13669, PBP2_TRAP_TM0322_like, Periplasmic component of TRAP-type C4-dicarboxylate transport system TM0322 from Thermotoga maritima and similar proteins; the type 2 periplasmic binding protein fold. This subgroup includes the hyperthermophilic bacterium Thermotoga maritima TRAP-type C4-dicarboxylate transport system TM0322 and its closely related proteins. TRAP transporters are a large family of solute transporters ubiquitously found in bacteria and archaea. They are comprised of a periplasmic substrate-binding protein (SBP; often called the P subunit) and two unequally sized integral membrane components: a large transmembrane subunit involved in the translocation process (the M subunit) and a smaller membrane of unknown function (the Q subunit). The driving force of TRAP transporters is provided by electrochemical ion gradients (either protons or sodium ions) across the cytoplasmic membrane, rather than ATP hydrolysis. This substrate-binding domain belongs to the type 2 periplasmic binding fold protein superfamily (PBP2). The PBP2 proteins are typically comprised of two globular subdomains connected by a flexible hinge and bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap.	3.46494e-145
NC_013654.1\|WP_000785832.1\|723339_724623_-\|citrate-(Si)-synthase	gnl\|CDD\|180164	PRK05614, gltA, citrate synthase.	0
NC_013654.1\|WP_000126143.1\|721982_723293_+\|TRAP-transporter-large-permease	gnl\|CDD\|224509	COG1593, DctQ, TRAP-type C4-dicarboxylate transport system, large permease component [Carbohydrate transport and metabolism].	2.11617e-118
NC_013654.1\|WP_000025458.1\|734214_735084_+\|succinate--CoA-ligase-subunit-alpha	gnl\|CDD\|180194	PRK05678, PRK05678, succinyl-CoA synthetase subunit alpha; Validated.	0
NC_013654.1\|WP_001237779.1\|721521_721983_+\|TRAP-transporter-small-permease	gnl\|CDD\|225632	COG3090, DctM, TRAP-type C4-dicarboxylate transport system, small permease component [Carbohydrate transport and metabolism].	2.66483e-21
NC_013654.1\|WP_000884361.1\|743579_745148_+\|cytochrome-ubiquinol-oxidase-subunit-I	gnl\|CDD\|185052	PRK15097, PRK15097, cytochrome bd-I ubiquinol oxidase subunit CydA.	0
NC_013654.1\|WP_000725054.1\|740843_742037_+\|tetratricopeptide-repeat-protein	gnl\|CDD\|276809	sd00006, TPR, Tetratricopeptide repeat. The Tetratricopeptide repeat (TPR) typically contains 34 amino acids and is found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi, plants, and humans. It is present in a variety of proteins including those involved in chaperone, cell-cycle, transcription, and protein transport complexes. The number of TPR motifs varies among proteins. Those containing 5-6 tandem repeats generate a right-handed helical structure with an amphipathic channel that is thought to accommodate an alpha-helix of a target protein. It has been proposed that TPR proteins preferentially interact with WD-40 repeat proteins, but in many instances several TPR-proteins seem to aggregate to multi-protein complexes.	1.01578e-17
NC_013654.1\|WP_000648958.1\|738012_740646_+\|mannosylglycerate-hydrolase	gnl\|CDD\|182093	PRK09819, PRK09819, mannosylglycerate hydrolase.	0

>NC_013654.1|WP_001235263.1|727843_728560_+|succinate-dehydrogenase-iron-sulfur-subunit-SdhB
MRLEFSIYRYNPDVDDAPRMQDYTLEAEEGRDMMLLDALIQLKEKDPSLSFRRSCREGVCGSDGLNMNGKNGLACITPISALNQPGKKIVIRPLPGLPVIRDLVVDMGQFYAQYEKIKPYLLNNGQNPPAREHLQMPEQREKLDGLYECILCACCSTSCPSFWWNPDKFIGPAGLLAAYRFLIDSRDTETDSRLDGLSDAFSVFRCHSIMNCVSVCPKGLNPTRAIGHIKSMLLQRNA
>NC_013654.1|WP_000775540.1|726061_727828_+|succinate-dehydrogenase-flavoprotein-subunit
MKLPVREFDAVVIGAGGAGMRAALQISQSGQTCALLSKVFPTRSHTVSAQGGITVALGNTHEDNWEWHMYDTVKGSDYIGDQDAIEYMCKTGPEAILELEHMGLPFSRLDDGRIYQRPFGGQSKNFGGEQAARTAAAADRTGHALLHTLYQQNLKNHTTIFSEWYALDLVKNQDGAVVGCTALCIETGEVVYFKARATVLATGGAGRIYQSTTNAHINTGDGVGMAIRAGVPVQDMEMWQFHPTGIAGAGVLVTEGCRGEGGYLLNKHGERFMERYAPNAKDLAGRDVVARSIMIEIREGRGCDGPWGPHAKLKLDHLGKEVLESRLPGILELSRTFAHVDPVKEPIPVIPTCHYMMGGIPTKVTGQALTVNEKGEDVVVPGLFAVGEIACVSVHGANRLGGNSLLDLVVFGRAAGLHLQESIAEQGALRDASESDVEASLDRLNRWNNNRNGEDPVAIRKALQECMQHNFSVFREGDAMAKGLEQLKVIRERLKNARLDDTSSEFNTQRVECLELDNLMETAYATAVSANFRTESRGAHSRFDFPDRDDENWLCHSLYLPESESMTRRSVNMEPKLRPAFPPKIRTY
>NC_013654.1|WP_000254365.1|725714_726062_+|succinate-dehydrogenase-membrane-anchor-subunit
MVSNASALGRNGVHDFILVRATAIVLTLYIIYMVGFFATSGELTYEVWIGFFASAFTKVFTLLALFSILIHAWIGMWQVLTDYVKPLALRLMLQLVIVVALVVYVIYGFVVVWGV
>NC_013654.1|WP_000263355.1|725316_725721_+|succinate-dehydrogenase-cytochrome-b556-subunit
MWALFMIRNVKKQRPVNLDLQTIRFPVTAIASILHRVSGVITFVAVGILLWLLGTSLSSPEGFEQASAIMGSFFVKFIMWGILTALAYHVVVGIRHMMMDFGYLEETFEAGKRSAKISFVITVVLSLLAGVLVW
>NC_013654.1|WP_001305582.1|724828_724936_-|hypothetical-protein
MRKSYEVGISPKINLCNSVEVLTNSFGTVISGRQV
>NC_013654.1|WP_000785832.1|723339_724623_-|citrate-(Si)-synthase
MADTKAKLTLNGDTAVELDVLKGTLGQDVIDIRTLGSKGVFTFDPGFTSTASCESKITFIDGDEGILLHRGFPIDQLATDSNYLEVCYILLNGEKPTQEQYDEFKTTVTRHTMIHEQITRLFHAFRRDSHPMAVMCGITGALAAFYHDSLDVNNPRHREIAAFRLLSKMPTMAAMCYKYSIGQPFVYPRNDLSYAGNFLNMMFSTPCEPYEVNPILERAMDRILILHADHEQNASTSTVRTAGSSGANPFACIAAGIASLWGPAHGGANEAALKMLEEISSVKHIPEFVRRAKDKNDSFRLMGFGHRVYKNYDPRATVMRETCHEVLKELGTKDDLLEVAMELENIALNDPYFIEKKLYPNVDFYSGIILKAMGIPSSMFTVIFAMARTVGWIAHWSEMHSDGMKIARPRQLYTGYAQRDFKSDIKK
>NC_013654.1|WP_000126143.1|721982_723293_+|TRAP-transporter-large-permease
MTALSELLAGSWLDNWLMIIPLMFVCLFINMPVWLAMFCGILTYFLCYSNVPLMVAIQRLIATTQTPSLLAIPFFILLGTLMSYTGIAARILQIANVLIGRMRGGLGGANILVSTMMGGVSASNLADAAMLSRMMVPEMEQKGYSRGFAAAITASGSLITPIIPPGIALILYGLVADVSIGSMFMAGILPGLLCSAMLIVTVWLVAIRRGLKPSSEHWPKPKEVSVALVQAWPALFLIVAVIGGIRANIFTPTEAGAVAVLLVMFIGFVIYRELKISHVFTALSETARSTASVMLIIMASAALGWIFSLERAGITVAEFVTSLTDNKYVFLLIINLLLLVLGMFLEGSAILLILVPLLKPVVAHFGIDPVHFGIIMILNLSLGTLSPPVGTVMLLVCNTVQVSVGQFMREAVPLLISLILLLLVITYIPAISLLLV
>NC_013654.1|WP_001237779.1|721521_721983_+|TRAP-transporter-small-permease
MRLLGKMIEVAAVLTLFILVIMTIAAVIMRYCFHMPLQWTEEVSGLLMIWVVMFGAVVAERDNTHLSIPFLADALTSRGQRILAFLVSLMSIILLVVMAWSAWKLAAGTAFKTTQILKISWFWIDIAVTVGAIGVACFTALQLIKKTPRKEGE
>NC_013654.1|WP_000735581.1|720493_721462_+|TRAP-transporter-substrate-binding-protein-DctP
MKKLLTPLLFLLALFSPMLNAAPVTIKIAYESNPGEPADTVVKHWAELVKKKSNGDIVFELYPSSQLGSKQDITEQALMGMNIITISDVGFLTDYDADLGILFGPYLTEDPQKLFAIYASDWFKQKEQKLREKGVHIVMSNYLYGTRQIIAKKPIRTPEDLKGMKIRVPNNVMQIKAIEAMGATPTPMPLGDVYPALTQGMIDGVENPVSVLYGQKLHEQAKYLSMVNYLTNTSLWLGGEAFFSTLTPAQLDIIHQTAYEAGLYSQKITTEQDATMLKTMQEQGVEIIYPDVAPFKEKALKVYQQFPEWTPGLYDTIQQQLK
>NC_013654.1|WP_000399432.1|719269_720466_+|UxaA-family-hydrolase
MEGYVRQNGRPGIRNTVQVIFMVECASHVAKKIAEGFPCHDVQYFGFSGCYPSDYGYRLVKNLATHSNVGGVLIISLGCENFDRRRLEQEVRESGRPCHTLVIQENKGTTNTITLGKQLVAEMLEQLADTPRCILNWSDLVVGTICGGSDGTSGITGNPAVGRAFDQLLEKGATCIFEESGELLGCEQHMMSRAASSQARDAIEVAMTKAERYYSLMGLGSFSNGNAEGGLTTQEEKSLGAYTKSGDALIAGVILPTQQTPFPGLWLMDVVPDGEPRFGYPNINDSSEALELIASGCHMVLFTTGRGSVIGSVIAPIIKVCNNPQTWEHLSDDMDVNAGRVISEGATLDDIADDIMQVIEHVANGQYCAAERLEHQEFVLTYKAFDYSKSAVCRADPR
>NC_013654.1|WP_001181475.1|728921_731723_+|2-oxoglutarate-dehydrogenase-E1-component
MQNSALKAWLDSSYLSGANQSWIEQLYEDFLTDPDSVDANWRSTFQQLPGTGVKPDQFHSQTREYFRRLAKDASRYSSTISDPDTNVKQVKVLQLINAYRFRGHQHANLDPLGLWQQDKVADLDPSFHDLTEADFQETFNVGSFASGKETMKLGELLEALKQTYCGPIGAEYMHITSTEEKRWIQQRIESGRATFNSEEKKRFLSELTAAEGLERYLGAKFPGAKRFSLEGGDALIPMLKEMIRHAGNSGTREVVLGMAHRGRLNVLVNVLGKKPQDLFDEFAGKHKEHLGTGDVKYHMGFSSDFQTDGGLVHLALAFNPSHLEIVSPVVIGSVRARLDRLDEPSSNKVLPITIHGDAAVTGQGVVQETLNMSKARGYEVGGTVRIVINNQVGFTTSNPLDARSTPYCTDIGKMVQAPIFHVNADDPEAVAFVTRLALDFRNTFKRDVFIDLVCYRRHGHNEADEPSATQPLMYQKIKKHPTPRKIYADKLEQEKVATLEDATEMVNLYRDALDAGDCVVAEWRPMNMHSFTWSPYLNHEWDEEYPNKVEMKRLQELAKRISTVPEAVEMQSRVAKIYGDRQAMAAGEKLFDWGGAENLAYATLVDEGIPVRLSGEDSGRGTFFHRHAVIHNQSNGSTYTPLQHIHNGQGAFRVWDSVLSEEAVLAFEYGYATAEPRTLTIWEAQFGDFANGAQVVIDQFISSGEQKWGRMCGLVMLLPHGYEGQGPEHSSARLERYLQLCAEQNMQVCVPSTPAQVYHMLRRQALRGMRRPLVVMSPKSLLRHPLAVSSLEELANGTFLPAISEIDELDPKGVKRVVMCSGKVYYDLLEQRRKNNQHDVAIVRIEQLYPFPHKAMQEVLQQFAHVKDFVWCQEEPLNQGAWYCSQHHFREVIPFGASLRYAGRPASASPAVGYMSVHQKQQQDLVNDALNVE
>NC_013654.1|WP_000099866.1|731737_732955_+|2-oxoglutarate-dehydrogenase-complex-dihydrolipoyllysine-residue-succinyltransferase
MSSVDILVPDLPESVADATVATWHKKPGDVVVRDEVLVEIETDKVVLEVPASADGILDAVLEDEGTTVTSRQILGRLREGNSAGKETSAKSEEKASTPAQRQQASLEEQNNDALSPAIRRLLAEHNLDASAIKGTGVGGRLTREDVEKHLAKAPAKESAPAAAAPAAQPALAARSEKRVPMTRLRKRVAERLLEAKNSTAMLTTFNEVNMKPIMDLRKQYGEAFEKRHGIRLGFMSFYVKAVVEALKRYPEVNASIDGDDVVYHNYFDVSMAVSTPRGLVTPVLRDVDTLGMADIEKKIKELAVKGRDGKLTVEDLTGGNFTITNGGVFGSLMSTPIINPPQSAILGMHAIKDRPMAVNGQVEILPMMYLALSYDHRLIDGRESVGFLVTIKELLEDPTRLLLDV
>NC_013654.1|WP_001048602.1|733048_734215_+|ADP-forming-succinate--CoA-ligase-subunit-beta
MNLHEYQAKQLFARYGLPAPVGYACTTPREAEEAASKIGAGPWVVKCQVHAGGRGKAGGVKVVNSKEDIRAFAENWLGKRLVTYQTDANGQPVNQILVEAATDIAKELYLGAVVDRSSRRVVFMASTEGGVEIEKVAEETPHLIHKVALDPLTGPMPYQGRELAFKLGLEGKLVQQFTKIFMGLATIFLERDLALIEINPLVITKQGDLICLDGKLGADGNALFRQPDLREMRDQSQEDPREAQAAQWELNYVALDGNIGCMVNGAGLAMGTMDIVKLHGGEPANFLDVGGGATKERVTEAFKIILSDDKVKAVLVNIFGGIVRCDLIADGIIGAVAEVGVNVPVVVRLEGNNAELGAKKLADSGLNIIAAKGLTDAAQQVVAAVEGK
>NC_013654.1|WP_000025458.1|734214_735084_+|succinate--CoA-ligase-subunit-alpha
MSILIDKNTKVICQGFTGSQGTFHSEQAIAYGTKMVGGVTPGKGGTTHLGLPVFNTVREAVAATGATASVIYVPAPFCKDSILEAIDAGIKLIITITEGIPTLDMLTVKVKLDEAGVRMIGPNCPGVITPGECKIGIQPGHIHKPGKVGIVSRSGTLTYEAVKQTTDYGFGQSTCVGIGGDPIPGSNFIDILEMFEKDPQTEAIVMIGEIGGSAEEEAAAYIKEHVTKPVVGYIAGVTAPKGKRMGHAGAIIAGGKGTADEKFAALEAAGVKTVRSLADIGEALKTVLK
>NC_013654.1|WP_000509910.1|735187_735910_-|mannosyl-D-glycerate-transport/metabolism-system-transcriptional-repressor-MngR
MGHKPLYRQIADRIREQITCGELKPGDALPTESALQTEFGVSRVTVRQALRQLVEQQILESIQGSGTYVKEERVNYDIFQLTSFDEKLSDRHVETHSEVLIFEVIPADNFLQQQLQISEQDRVWHVKRVRYRKQKPVALEETWMPLALFPDLTWQVMENSKYHFIEEVKKMVIDRSEQEIIPLMPTEEMSRLLNISQTKPILEKVSRGYLVDGQVFEYSRNAFNTDDYKFTLIAQRKSPR
>NC_013654.1|WP_001054880.1|736078_737995_+|PTS-2-O-a-mannosyl-D-glycerate-transporter-subunit-IIABC
MNLTTLTHRDALCLNVRFTSREEAIHALTQRLAALGKISSTEQFLEEVYCRESLGPTALGEGLAVPHGKTAAVKEAAFAVATLSEPLQWEGVDGPEAVDLVVLLAIPPNEAGTTHMKLLTALTTRLADDELRARIQSATTPDELLSALDDKGDAQHTASFSYAPTIVCVTACPAGIAHTYMAAEYLEKAGRKLGVNIYVEKQGANGIEERLTAEQLNSATACIFAAEVAIKESERFNGIPALSVPVAEPIRHAEALIQQALTLKRSDETRTVQQDTQPVKSVKTELKQALLSGISFAVPLIVAGGTVLAVAVLLSQIFGLQDLFNEENSWLWMYRKLGGGMLGILMVPVLAAYTAYSLADKPALAPGFAAGLAANMIGSGFLGAVVGGLIAGYLMRWVKNHLRLSSKFNGFLTFYLYPVLGTLGAGSLMLFVVGEPVAWINNSLTAWLNVLSGNNALLLGAILGFMCSFDLGGPVNKAAYAFCLGAMANGVYGPYAIFASVKMVSAFTVTASTMLAPRLFKEFEIETGKSTWLLGLAGITEGAIPMAIEDPLRVIGSFVLGSMVTGAIVGAMNIGLSTPGAGIFSLFLLHDNGAGGVMAAIGWFGAALVGAAISTAILLIWRHHAVKHGNYLTDGVMP
>NC_013654.1|WP_000648958.1|738012_740646_+|mannosylglycerate-hydrolase
MKAVSRVHITPHMHWDREWYFTTEESRILLVNNMEEILCRLEQDNEYKYYVLDGQTAILEDYFAVKPENKDRVKKLVEGGKLIIGPWYTQTDTTIVSAESIVRNLMYGMRDCLAFGEPMKIGYLPDSFGMSGQLPHIYNGFGITRTMFWRGCSERHGTDKTEFLWQSSDGSEVTAQVLPLGYAIGKYLPADENGLRKRLDSYFDVLEKASVTKEILLPNGHDQMPLQQNIFEVMEKLREIYPQRKFVMSRFEEVFEQIEAQRESLAILKGEFIDGKYMRVHRTIGSTRMDIKIAHARIENKIVNLLEPLATLAWTLGFDYHHGLLEKMWKEILKNHAHDSIGCCCSDKVHREIVARFELAEDMADNLIRFYMRKIADNMPQSDADKLVLFNLMPWPREEVINTTVRLRGSQFNLRDGRGQPVPYFIRHAREIDPGLIDRQIVHYGNYDPFMEFDIQISQIVPSMGYRTLYIEANQPGNVVTPKSKTEGILENAFWQIALNEDGSLRLVDKDSGVRYDRVFQIEEGSDDGDEYDYSPAKEEWAITSANAKPQYDIIHEAWQSRAIIRYEIAVPRNLSERRAKQCSGRVGVETVITLSHNSRRIDADINLDNQADDHRIRVLIPTPFNTDVVLADTQFGSLTRPVKDCAMNVWQQEGWKEAPVPVWNMLNYAVLQEGRNGIAVFSEGLREFEVIGEENKTFAITLLRGVGLLGKEDLLLRPGRPSGIKMPVSDSQLRGSFSCRLSLFSYIGTPVTAGVAQQARAWLTPVQCYNKIPWDAMKLNKAKFNVPESYSLLKMPPVGCLISALKKAEDRQELILRLFNPAELTSCDATVAFSRKVMTCTETMMNERFNTEKNEVLKELALFLPGQSRTFSYRIV
>NC_013654.1|WP_000725054.1|740843_742037_+|tetratricopeptide-repeat-protein
MKKIVLPVALALLGMNAGAYAADVSIDILSATVKDKRIEGASVTLQRNGAQSVSGITNTSGSISLGTSFADNKDALLIVKKEGYSNLVVKCPCAGMTYAISPVMTNLDGMRVVLSWGEKPFDLDSHLIFPGGHIYFDSKEGTDANLDVDDTDSYGPETVTISKKHFGESYIYAVQDYSNKGLPNSNYLSASKAKVFVYVGSSLVRSYSVPAGKRGNIWTVFKLNPNGEFEDINSVTSANFNGTTLDVRDLATVIMPATDSSAPASPAMQNSGDTQLARKYNREGEAVYKTGQLEQAIQLFQQATELDGNYGQAFSNLGLAYQKNGNIAEAIWANRKAISLASGVNAATTRANSYYNIAKIYETSGQNAEALQHYQLAYTEKNKPSYEEAIARVKTKM
>NC_013654.1|WP_000884361.1|743579_745148_+|cytochrome-ubiquinol-oxidase-subunit-I
MLDIVELSRLQFALTAMYHFLFVPLTLGMAFLLAIMETVYVLSGKQIYKDMTKFWGKLFGINFALGVATGLTMEFQFGTNWSYYSHYVGDIFGAPLAIEGLMAFFLESTFVGLFFFGWDRLGKVQHMCVTWLVALGSNLSALWILVANGWMQNPIASDFNFETMRMEMVSFSELVLNPVAQVKFVHTVASGYVTGAMFILGISAWYMLKGRDFAFAKRSFAIAASFGMAAVLSVIVLGDESGYEMGDVQKTKLAAIEAEWETQPAPAAFTLFGIPDQEEETNKFAIQIPYALGIIATRSVDTPVIGLKELMVQHEERIRNGMKAYSLLEQLRSGSTDQAVRDQFNSMKKDLGYGLLLKRYTPNVADATEAQIQQATKDSIPRVAPLYFAFRIMVACGFLLLAIIALSFWSVIRNRIGEKKWLLRAALYGIPLPWIAVEAGWFVAEYGRQPWAIGEVLPTAVANSSLTAGDLIFSMVLICGLYTLFLVAELFLMFKFARLGPSSLKTGRYHFEQSSTTTQPAR
>NC_013654.1|WP_000568275.1|745163_746303_+|cytochrome-d-ubiquinol-oxidase-subunit-II
MIDYEVLRFIWWLLVGVLLIGFAVTDGFDMGVGMLTRFLGRNDTERRIMINSIAPHWDGNQVWLITAGGALFAAWPMVYAAAFSGFYVAMILVLASLFFRPVGFDYRSKIEETRWRNMWDWGIFIGSFVPPLVIGVAFGNLLQGVPFNVDEYLRLYYTGNFFQLLNPFGLLAGVVSVGMIITQGATYLQMRTVGELHLRTRATAQVAALVTLVCFALAGVWVMYGIDGYVVKSTMDHYAASNPLNKEVVREAGAWLVNFNNTPILWAIPALGVVLPLLTILTARMDKAAWAFVFSSLTLACIILTAGIAMFPFVMPSSTMMNASLTMWDATSSQLTLNVMTWVAVVLVPIILLYTAWCYWKMFGRITKEDIERNTHSLY

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Crispr_ID: NC_013654_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_013654_2

894815-894897

Orphan

I-F

Consensus_repeat	Method
AGTTCACTGCCGTACAGGCAGCT	CRISPRCasFinder

1 spacers

The CRISPR arrays of NC_013654_2

>merge|NC_013654|2|894815-894897|CRISPRCasFinder
AGTTCACTGCCGTACAGGCAGCTTAGAAATTGCCGCGGATCCTGTCTGCCAATAATGACAAGTTCACTGCCGTACAGGCAGAT

>NC_013654|2|2|894815-894897|CRISPRCasFinder
AGTTCACTGCCGTACAGGCAGCT	TAGAAATTGCCGCGGATCCTGTCTGCCAATAATGACA
AGTTCACTGCCGTACAGGCAGAT

Protein	Signature genes	Signature genes Name	Protein_function
NC_013654.1\|WP_001043561.1\|898258_900025_-\|cysteine/glutathione-ABC-transporter-permease/ATP-binding-protein-CydD	unknown	unknown	gnl\|CDD\|236870
NC_013654.1\|WP_001295343.1\|906550_907162_+\|outer-membrane-lipoprotein-chaperone-LolA	unknown	unknown	gnl\|CDD\|129638
NC_013654.1\|WP_001351020.1\|887190_888147_-\|DUF535-domain-containing-protein	unknown	unknown	gnl\|CDD\|225537
NC_013654.1\|WP_000410785.1\|891428_891653_-\|cold-shock-like-protein-CspD	unknown	unknown	gnl\|CDD\|77494
NC_013654.1\|WP_000488716.1\|884415_885111_-\|aquaporin-Z	unknown	unknown	gnl\|CDD\|235453
NC_013654.1\|WP_000491137.1\|883101_884001_-\|L-lysine-exporter-LysO	unknown	unknown	gnl\|CDD\|225287
NC_013654.1\|WP_000067797.1\|907172_908516_+\|replication-associated-recombination-protein-RarA	unknown	unknown	gnl\|CDD\|237355
NC_013654.1\|WP_001385255.1\|900147_901113_-\|thioredoxin-disulfide-reductase	unknown	unknown	gnl\|CDD\|182343
NC_013654.1\|WP_001040187.1\|895287_895506_-\|translation-initiation-factor-IF-1	unknown	unknown	gnl\|CDD\|178954
NC_013654.1\|WP_000746478.1\|888297_889413_+\|macrolide-transporter-subunit-MacA	unknown	unknown	gnl\|CDD\|183211
NC_013654.1\|WP_001241674.1\|895790_896495_-\|leucyl/phenylalanyl-tRNA--protein-transferase	unknown	unknown	gnl\|CDD\|234720
NC_013654.1\|WP_000520775.1\|891975_892296_+\|ATP-dependent-Clp-protease-adapter-ClpS	unknown	unknown	gnl\|CDD\|178809
NC_013654.1\|WP_000077084.1\|902285_906392_+\|DNA-translocase-FtsK	unknown	unknown	gnl\|CDD\|236669
NC_013654.1\|WP_000886683.1\|908606_909899_+\|serine--tRNA-ligase	unknown	unknown	gnl\|CDD\|235461
NC_013654.1\|WP_000188152.1\|889409_891356_+\|macrolide-ABC-transporter-ATP-binding-protein/permease-MacB	unknown	unknown	gnl\|CDD\|182528
NC_013654.1\|WP_000599803.1\|885535_887194_+\|ATP-dependent-endonuclease	unknown	unknown	gnl\|CDD\|226121
NC_013654.1\|WP_000934041.1\|892326_894603_+\|ATP-dependent-Clp-protease-ATP-binding-subunit-ClpA	unknown	unknown	gnl\|CDD\|236828
NC_013654.1\|WP_000228473.1\|901656_902151_+\|leucine-responsive-transcriptional-regulator-Lrp	unknown	unknown	gnl\|CDD\|183009
NC_013654.1\|WP_000458841.1\|881305_882958_-\|hydroxylamine-reductase	unknown	unknown	gnl\|CDD\|235391
NC_013654.1\|WP_001202204.1\|896536_898258_-\|cysteine/glutathione-ABC-transporter-ATP-binding-protein/permease-CydC	unknown	unknown	gnl\|CDD\|236865

Protein	Function_ID	Function_description	E-value
NC_013654.1\|WP_001043561.1\|898258_900025_-\|cysteine/glutathione-ABC-transporter-permease/ATP-binding-protein-CydD	gnl\|CDD\|236870	PRK11174, PRK11174, cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed.	0
NC_013654.1\|WP_001295343.1\|906550_907162_+\|outer-membrane-lipoprotein-chaperone-LolA	gnl\|CDD\|129638	TIGR00547, Outer-membrane_lipoprotein_carrier_protein, periplasmic chaperone LolA. This protein, LolA, is known so far only in the gamma and beta subdivisions of the Proteobacteria. The E. coli major outer lipoprotein (Lpp) of E. coli is released from the inner membrane as a complex with this chaperone in an energy-requiring process, and is then delivered to LolB for insertion into the outer membrane. LolA is involved in the delivery of lipoproteins generally, rather than just Lpp, and is an essential protein in E. coli, unlike Lpp itself. [Protein fate, Protein and peptide secretion and trafficking].	1.48786e-125
NC_013654.1\|WP_001351020.1\|887190_888147_-\|DUF535-domain-containing-protein	gnl\|CDD\|225537	COG2990, VirK, Uncharacterized protein conserved in bacteria [Function unknown].	3.43529e-131
NC_013654.1\|WP_000410785.1\|891428_891653_-\|cold-shock-like-protein-CspD	gnl\|CDD\|77494	PRK09937, PRK09937, cold shock-like protein CspD.	1.48016e-47
NC_013654.1\|WP_000488716.1\|884415_885111_-\|aquaporin-Z	gnl\|CDD\|235453	PRK05420, PRK05420, aquaporin Z; Provisional.	7.82992e-144
NC_013654.1\|WP_000491137.1\|883101_884001_-\|L-lysine-exporter-LysO	gnl\|CDD\|225287	COG2431, COG2431, Predicted membrane protein [Function unknown].	3.40497e-117
NC_013654.1\|WP_000067797.1\|907172_908516_+\|replication-associated-recombination-protein-RarA	gnl\|CDD\|237355	PRK13342, PRK13342, recombination factor protein RarA; Reviewed.	0
NC_013654.1\|WP_001385255.1\|900147_901113_-\|thioredoxin-disulfide-reductase	gnl\|CDD\|182343	PRK10262, PRK10262, thioredoxin reductase; Provisional.	0
NC_013654.1\|WP_001040187.1\|895287_895506_-\|translation-initiation-factor-IF-1	gnl\|CDD\|178954	PRK00276, infA, translation initiation factor IF-1; Validated.	8.41354e-49
NC_013654.1\|WP_000746478.1\|888297_889413_+\|macrolide-transporter-subunit-MacA	gnl\|CDD\|183211	PRK11578, PRK11578, macrolide transporter subunit MacA; Provisional.	0
NC_013654.1\|WP_001241674.1\|895790_896495_-\|leucyl/phenylalanyl-tRNA--protein-transferase	gnl\|CDD\|234720	PRK00301, aat, leucyl/phenylalanyl-tRNA--protein transferase; Reviewed.	1.92039e-139
NC_013654.1\|WP_000520775.1\|891975_892296_+\|ATP-dependent-Clp-protease-adapter-ClpS	gnl\|CDD\|178809	PRK00033, clpS, ATP-dependent Clp protease adaptor protein ClpS; Reviewed.	3.7104e-49
NC_013654.1\|WP_000077084.1\|902285_906392_+\|DNA-translocase-FtsK	gnl\|CDD\|236669	PRK10263, PRK10263, DNA translocase FtsK; Provisional.	0
NC_013654.1\|WP_000886683.1\|908606_909899_+\|serine--tRNA-ligase	gnl\|CDD\|235461	PRK05431, PRK05431, seryl-tRNA synthetase; Provisional.	0
NC_013654.1\|WP_000188152.1\|889409_891356_+\|macrolide-ABC-transporter-ATP-binding-protein/permease-MacB	gnl\|CDD\|182528	PRK10535, PRK10535, macrolide ABC transporter ATP-binding protein/permease MacB.	0
NC_013654.1\|WP_000599803.1\|885535_887194_+\|ATP-dependent-endonuclease	gnl\|CDD\|226121	COG3593, COG3593, Predicted ATP-dependent endonuclease of the OLD family [DNA replication, recombination, and repair].	0
NC_013654.1\|WP_000934041.1\|892326_894603_+\|ATP-dependent-Clp-protease-ATP-binding-subunit-ClpA	gnl\|CDD\|236828	PRK11034, clpA, ATP-dependent Clp protease ATP-binding subunit; Provisional.	0
NC_013654.1\|WP_000228473.1\|901656_902151_+\|leucine-responsive-transcriptional-regulator-Lrp	gnl\|CDD\|183009	PRK11169, PRK11169, leucine-responsive transcriptional regulator Lrp.	5.32926e-117
NC_013654.1\|WP_000458841.1\|881305_882958_-\|hydroxylamine-reductase	gnl\|CDD\|235391	PRK05290, PRK05290, hybrid cluster protein; Provisional.	0
NC_013654.1\|WP_001202204.1\|896536_898258_-\|cysteine/glutathione-ABC-transporter-ATP-binding-protein/permease-CydC	gnl\|CDD\|236865	PRK11160, PRK11160, cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed.	0

>NC_013654.1|WP_000934041.1|892326_894603_+|ATP-dependent-Clp-protease-ATP-binding-subunit-ClpA
MLNQELELSLNMAFARAREHRHEFMTVEHLLLALLSNPSAREALEACSVDLVALRQELEAFIEQTTPVLPASEEERDTQPTLSFQRVLQRAVFHVQSSGRNEVTGANVLVAIFSEQESQAAYLLRKHEVSRLDVVNFISHGTRKDEPTQSSDPGSQPNSEEQAGGEERMENFTTNLNQLARVGGIDPLIGREKELERAIQVLCRRRKNNPLLVGESGVGKTAIAEGLAWRIVQGDVPEVMADCTIYSLDIGSLLAGTKYRGDFEKRFKALLKQLEQDTNSILFIDEIHTIIGAGAASGGQVDAANLIKPLLSSGKIRVIGSTTYQEFSNIFEKDRALARRFQKIDITEPSIEETVQIINGLKPKYEAHHDVRYTAKAVRAAVELAVKYINDRHLPDKAIDVIDEAGARARLMPVSKRKKTVNVADIESVVARIARIPEKSVSQSDRDTLKNLGDRLKMLVFGQDKAIEALTEAIKMARAGLGHEHKPVGSFLFAGPTGVGKTEVTVQLSKALGIELLRFDMSEYMERHTVSRLIGAPPGYVGFDQGGLLTDAVIKHPHAVLLLDEIEKAHPDVFNILLQVMDNGTLTDNNGRKADFRNVVLVMTTNAGVRETERKSIGLIHQDNSTDAMEEIKKIFTPEFRNRLDNIIWFDHLSTDVIHQVVDKFIVELQVQLDQKGVSLEVSQEARNWLAEKGYDRAMGARPMARVIQDNLKKPLANELLFGSLVDGGQVTVALDKEKNELTYGFQSAQKHKAEAAH
>NC_013654.1|WP_000520775.1|891975_892296_+|ATP-dependent-Clp-protease-adapter-ClpS
MGKTNDWLDFDQLAEEKVRDALKPPSMYKVILVNDDYTPMDFVIDVLQKFFSYDVERATQLMLAVHYQGKAICGVFTAEVAETKVAMVNKYARENEHPLLCTLEKA
>NC_013654.1|WP_000410785.1|891428_891653_-|cold-shock-like-protein-CspD
MEKGTVKWFNNAKGFGFICPEGGGEDIFAHYSTIQMDGYRTLKAGQSVQFDVHQGPKGNHASVIVPVEVEAAVA
>NC_013654.1|WP_000188152.1|889409_891356_+|macrolide-ABC-transporter-ATP-binding-protein/permease-MacB
MTPLLELKDIRRSYPAGDEQVEVLKGISLDIYAGEMVAIVGASGSGKSTLMNILGCLDKATSGTYRVAGQDVATLDADALAQLRREHFGFIFQRYHLLSHLTAEQNVEVPAVYAGLEWKQRLLRAQELLQRLGLEDRTEYYPAQLSGGQQQRVSIARALMNGGQVILADEPTGALDSHSGEEVMAILHQLRDRGHTVIIVTHDPQVAAQAERVIEIRDGEIVRNPPAIEKVNATGGTEPVVNTASGWRQFVSGFNEALTMAWRALAANKMRTLLTMLGIIIGIASVVSIVVVGDAAKQMVLADIRSIGTNTIDVYPGKDFGDDDPQYQQALKYDDLIAIQKQPWVASATPAVSQNLRLRYNNVDVAASANGVSGDYFNVYGMTFSEGNTFNQEQLNGRAQVVVLDSNTRRQLFPHKADVVGEVILVGNMPARVIGVAEEKQSMFGSSKVLRVWLPYSTMSGRVMGQSWLNSITVRVKEGFDSAEAEQQLTRLLSLRHGKKDFFTWNMDGVLKTVEKTTRTLQLFLTLVAVISLVVGGIGVMNIMLVSVTERTREIGIRMAVGARASDVLQQFLIEAVLVCLVGGALGITLSLLIAFTLQLFLPGWEIGFSPLALLLAFLCSTVTGILFGWLPARNAARLDPVDALARE
>NC_013654.1|WP_000746478.1|888297_889413_+|macrolide-transporter-subunit-MacA
MKKRKTVKKRYVIAMVIVIAGLITLWRILNAPVPTYQTLIVRPGDLQQSVLATGKLDALRKVDVGAQVSGQLKTLSVAIGDKVKKDQLLGVIDPEQAENQIKEVEATLMELRAQRQQAEAELKLARVTYSRQQRLAQTQAVSQQDLDNAATEMAVKQAQIGTIDAQIKRNQASLDTAKTNLDYTRIVAPMAGEVTQITTLQGQTVIAAQQAPNILTLADMSTMLVKAQVSEADVIHLKPGQKAWFTVLGDPLTRYEGQIKDVLPTPEKINDAIFYYARFEVPNPNGLLRLDMTAQVHIQLTDVKNVLTIPLSALGDPVGDNRYKVKLLRNGETREREVTIGARNDTDVEIVKGLEAGDEVVIGEAKPGAAQ
>NC_013654.1|WP_001351020.1|887190_888147_-|DUF535-domain-containing-protein
MNMSQLTERTFTPSESLSSLSLFLSLARGQCRPGKFWHRRSFRQKFLLRSLIMPRLSVEWMNELSHWPNLNVLLTRQPRLPVRLHRPYLAANLSRKQLLEALRYHYALLRGCMSAEEFSLYLNTPGLQLAKLEGKNGEQFTLELTMMISMDKEGDSTILFRNSEGIPLAELTFTLCEYQGKRTMFIGGLQGAKWEIPHQEIQNATKACHGLFPKRLVMEAACLFAQRLQVEQIIAVSNETHIYRSLRYRDKEGKIHADYNAFWESVGGVCDAERHYRLPAQIARKEIAEIASKKRAEYRRRYEMLDAIQPQMATMFCS
>NC_013654.1|WP_000599803.1|885535_887194_+|ATP-dependent-endonuclease
MILERVEIVGFRGINRLSLMLEQNNVLIGENAWGKSSLLDALTLLLSPESDLYHFERDDFWFPPGDINGREHHLHIILTFRESLPGRHRVRRYRPLEACWTPCTDGYHRIFYRLEGESAEDGSVMTLRSFLDKDGHPIDVEDINDQARHLVRLMPVLRLRDARFMRRIRNGTVPNVPNVEVTARQLDFLARELSSHPQNLSDGQIRQGLSAMVQLLEHYFSEQGAGQARYRLMRRRASNEQRSWRYLDIINRMIDRPGGRSYRVILLGLFATLLQAKGTLRLDKDARPLLLIEDPETRLHPIMLSVAWHLLNLLPLQRIATTNSGELLSLTPVEHVCRLVRESSRVAAWRLGPSGLSTEDSRRISFHIRFNRPSSLFARCWLLVEGETETWVINELARQCGHHFDAEGIKVIEFAQSGLKPLVKFARRMGIEWHVLVDGDEAGKKYAATVRSLLNNDREAEREHLTALPALDMEHFMYRQGFSDVFHRVAQIPENIPMNLRKIISKAIHRSSKPDLAIEVAMEAGRRGVDSVPTLLKKMFSRVLWLARGRAD
>NC_013654.1|WP_000488716.1|884415_885111_-|aquaporin-Z
MFRKLAAECFGTFWLVFGGCGSAVLAAGFPELGIGFAGVALAFGLTVLTMAFAVGHISGGHFNPAVTIGLWAGGRFPAKEVVGYVIAQVVGGIVAAALLYLIASGKTGFDAAASGFASNGYGEHSPGGYSMLSALVVELVLSAGFLLVIHGATDKFAPAGFAPIAIGLALTLIHLISIPVTNTSVNPARSTAVAIFQGGWALEQLWFFWVVPIVGGIIGGLIYRTLLEKRN
>NC_013654.1|WP_000491137.1|883101_884001_-|L-lysine-exporter-LysO
MFSGLLIILVPLIVGYLIPLRQKAALRVINQLLSWMVYLILFFMGISLAFLDNLASNLLAILHYSAVSTTVILLCNIAALMWLERGLPWSNHHQQEKLPSRIAMALESLKLCGVVVIGFAIGLSGLAFLQHATEASEYTLILLLFLVGIQLRNNGMTLKQIVLNRRGMIVAVVVVASSLIGGLINAFILDLPINTALAMASGFGWYSLSGILLTESFGPVIGSAAFFNDLARELIAIMLIPGLIRRSRSTALGLCGATSMDFTLPVLQRTGGLDMVPAAIVHGFILSLLVPILIAFFSA
>NC_013654.1|WP_000458841.1|881305_882958_-|hydroxylamine-reductase
MFCVQCEQTIRTPAGNGCSYAQGMCGKTAETSDLQDLLIATLQGLSAWAVKAREYGIINHDVDSFAPRAFFSTLTNVNFDSPRIIGYAREAIALREALKAQCLAVDANARVDNPMADLQLVSDDLGELQRQAAEFTPNKDKAAIGENILGLRLLCLYGLKGAAAYMEHAHVLGQYDNDIYAQYHKIMAWLGTWPADMNALLECSMEIGQMNFKVMSILDAGETGKYGHPTPTQVNVKATAGKCILISGHDLKDLYNLLEQTEGTGVNVYTHGEMLPAHGYPELRKFKHLVGNYGSGWQNQQVEFARFPGPIVMTSNCIIDPTVGAYDDRIWTRSIVGWPGVRHLDGEDFSAVIAQAQQMAGFPYSEIPHLITVGFGRQTLLGAADTLIDLVSREKLRHIFLLGGCDGARGERHYFTDFATSVPDDCLILTLACGKYRFNKLEFGDIEGLPRLVDAGQCNDAYSAIILAVTLAEKLGCGVNDLPLSLVLSWFEQKAIVILLTLLSLGVKNIVTGPTAPGFLTPDLLAVLNEKFGLRSITTVEEDMKQLLSA
>NC_013654.1|WP_001040187.1|895287_895506_-|translation-initiation-factor-IF-1
MAKEDNIEMQGTVLETLPNTMFRVELENGHVVTAHISGKMRKNYIRILTGDKVTVELTPYDLSKGRIVFRSR
>NC_013654.1|WP_001241674.1|895790_896495_-|leucyl/phenylalanyl-tRNA--protein-transferase
MRLVQLSRHSIAFPSPEGALREPNGLLALGGDLSPARLLMAYQRGIFPWFSPGDPILWWSPDPRAVLWPESLHISRSMKRFHKRSPYRVTMNYAFGQVIEGCASDREEGTWITRGVVEAYHRLHELGHAHSIEVWREDELVGGMYGVAQGTLFCGESMFSRMENASKTALLVFCDEFIRHGGKLIDCQVLNDHTASLGACEIPRRDYLNYLNQMRLGRLSNNFWVPRCLFSPQE
>NC_013654.1|WP_001202204.1|896536_898258_-|cysteine/glutathione-ABC-transporter-ATP-binding-protein/permease-CydC
MRALLPYLALYKRHKWMLSLGIVLAIVTLLASIGLLTLSGWFLSASAVAGVAGLYSFNYMLPAAGVRGAAITRTAGRYFERLVSHDATFRVLQHLRIYTFSKLLPLSPAGLARYRQGELLNRVVADVDTLDHLYLRVISPLVGAFVVIMVVTIGLSFLDFTLAFTLGGIMLLTLFLMPPLFYRAGKSTGQNLTHLRGQYRQQLTAWLQGQAELTIFGASDRYRTQLENTEIQWLEAQRRQSELTALSQAIMLLIGALAVILMLWMASGGVGGNAQPGALIALFVFCALAAFEALAPVTGAFQHLGQVIASAVRITDLTDQKPKVTFPDTQTRVADRVSLTLRDVQFTYPEQSQQALKGIYLQVNAGEHIAILGRTGCGKSTLLQLLTRAWDPQQGEILLNDSPIASLNEAALRQTISVVPQRVHLFSATLRDNLLLASPGSSDEALAEILRRVGLEKLLEDAGLNSWLGEGGRQLSGGELRRLAIARALLHDAPLVLLDEPTEGLDATTESQILELLAEMMCEKTVLMVTHRLRGLSRFQQIIVMDNGQIIEQGTHAELLARQGRYYQFKQGL
>NC_013654.1|WP_001043561.1|898258_900025_-|cysteine/glutathione-ABC-transporter-permease/ATP-binding-protein-CydD
MNKSRQKELTRWLKQQSVISQRWLNISRLLGFVSGILIIAQAWFMARILQHMIMENIPREALLLPFTLLFLTFVLRAWVVWLRERVGYHAGQHIRFAIRRQVLDRLQQAGPAWIQGKPAGSWATLVLEQIDDMHDYYARYLPQMALAVSVPLLIVVAIFPSNWAAALILLGTAPLIPLFMALVGMGAADANRRNFLALARLSGHFLDRLRGMETLRIFGRGEAEIESIRSASEDFRQRTMEVLRLAFLSSGILEFFTSLSIALVAVYFGFSYLGELDFGHYDTGVTLAAGFLALILAPEFFQPLRDLGTFYHAKAQAVGAADSLKTFMETPLAHPQRGEAELASTDPVTIEAEDLFITSPEGKTLAGPLNFTLPAGQRAVLVGRSGSGKSSLLNALSGFLSYQGSLRINGIELRDLSPESWRKHLSWVGQNPQLPAATLRDNVLLARPDASEQELQTALDNAWVSEFLPLLPQGVDTPVGDQAARLSVGQAQRVAVARALLNPCSLLLLDEPAASLDAHSEQRVMEALNAASLRQTTLMVTHQLEDLADWDVIWVMQDGQIIEQGRYAELSVAGGPFATLLAHRQEEI
>NC_013654.1|WP_001385255.1|900147_901113_-|thioredoxin-disulfide-reductase
MGTTKHSKLLILGSGPAGYTAAVYAARANLQPVLITGMEKGGQLTTTTEVENWPGDPNDLTGPLLMERMHEHATKFETEIIFDHINKVDLQNRPFRLTGDSGEYTCDALIIATGASARYLGLPSEEAFKGRGVSACATCDGFFYRNQKVAVIGGGNTAVEEALYLSNIASEVHLIHRRDGFRAEKILIKRLMDKVENGNIILHTNRTLEEVTGDQMGVTGVRLRDTQNTDNIESLDVAGLFVAIGHSPNTAIFEGQLELENGYIKVQSGIHGNATQTSIPGVFAAGDVMDHIYRQAITSAGTGCMAALDAERYLDGLADAK
>NC_013654.1|WP_000228473.1|901656_902151_+|leucine-responsive-transcriptional-regulator-Lrp
MVDSKKRPGKDLDRIDRNILNELQKDGRISNVELSKRVGLSPTPCLERVRRLERQGFIQGYTALLNPHYLDASLLVFVEITLNRGAPDVFEQFNTAVQKLEEIQECHLVSGDFDYLLKTRVPDMSAYRKLLGETLLRLPGVNDTRTYVVMEEVKQSNRLVIKTR
>NC_013654.1|WP_000077084.1|902285_906392_+|DNA-translocase-FtsK
MSQEYTEDKEVTLTKLSSGRRLLEALLILIVLFAVWLMAALLSFNPSDPSWSQTAWHEPIHNLGGMPGAWLADTLFFIFGVMAYTIPVIIVGGCWFAWRHQSSDEYIDYFAVSLRIIGVLALILTSCGLAAINADDIWYFASGGVIGSLLSTTLQPLLHSSGGTIALLCVWAAGLTLFTGWSWVTIAEKLGGWILNILTFASNRTRRDDTWVDEDEYEDDEEYEDENHGKQHESRRARILRGALARRKRLAEKFINPMGRQTDAALFSGKRMDDDEEITYTVRGVAADPDDVLFSGNRATQPEYDEYDPLLNGAPITEPVAVAAAATTATQSWAAPVEPVTQTPPVASVDVPPAQSTVAWQPVPGPQTGEPVIAPAPEGYPQQPQYAQPAVQYNEPLQQPVQPQQPYYAPAAEQPAQQPYYAPAAEQPVQQPYYATAAEQPAQQPYYAPAPEQAVAGNAWQAEEQQSTFAPQSTYQTEQTYQQPAAQEPLYQQPQPVEQQPVVEPEPVVEETKPTRPPLYYFEEVEEKRAREREQLAAWYQPIPEPVKEPEPIKSSLKAPSVAAVPPVEAAAAVSPLASGVKKATLATGAAATVAAPVFSLANSGGPRPQVKEGIGPQLPRPKRIRVPTRRELASYGIKLPSQRAAEEKAREAQRNQYDSGDQYNDDEIDAMQQDELARQFAQTQQQRYGEQYQHDVPVNTEDADAAAEAELARQFAQTQQQRYSGEQPAGANPFSLDDFEFSPMKALLDDGPHEPLFTPIVEPVQQPQQPVAPQQQYQQPQQPVAPQPQYQQPQQPVAPQQQYQQPQQPVAQQPQYQQPQQPVTQQPQYQQPQQPVVPQPQYQQPQQPVAPQPQDTLLHPLLMRNGDSRPLHKPTTPLPSLDLLTPPPSEVEPVDTFALEQMARLVEARLADFRIKADVVNYSPGPVITRFELNLAPGVKAARISNLSRDLARSLSTVAVRVVEVIPGKPYVGLELPNKKRQTVYLREVLDNAKFRDNPSPLTVVLGKDIAGEPVVADLAKMPHLLVAGTTGSGKSVGVNAMILSMLYKAQPEDVRFIMIDPKMLELSVYEGIPHLLTEVVTDMKDAANALRWCVNEMERRYKLMSALGVRNLAGYNEKIAEADRMMRPIPDPYWKPGDSMDAQHPVLKKEPYIVVLVDEFADLMMTVGKKVEELIARLAQKARAAGIHLVLATQRPSVDVITGLIKANIPTRIAFTVSSKIDSRTILDQAGAESLLGMGDMLYSGPNSTLPVRVHGAFVRDQEVHAVVQDWKARGRPQYVDGITSDSESEGGAGGFDGAEELDPLFDQAVQFVTEKRKASISGVQRQFRIGYNRAARIIEQMEAQGIVSEQGHNGNREVLAPPPFD
>NC_013654.1|WP_001295343.1|906550_907162_+|outer-membrane-lipoprotein-chaperone-LolA
MKKIAITCALLSSLVASSVWADAASDLKSRLDKVSSFHASFTQKVTDGSGAAVQEGQGDLWVKRPNLFNWHMTQPDESILVSDGKTLWFYNPFVEQATATWLKDATGNTPFMLIARNQSSDWQQYNIKQNGDDFVLTPKASNGNLKQFTINVGRDGTIHQFSAVEQDDQRSSYQLKSQQNGAVDAAKFTFTPPQGVTVDDQRK
>NC_013654.1|WP_000067797.1|907172_908516_+|replication-associated-recombination-protein-RarA
MSNLSLDFSDNTFQPLAARMRPENLAQYIGQQHLLAVGKPLPRAIEAGHLHSMILWGPPGTGKTTLAEVIARYANADVERISAVTSGVKEIREAIERARQNRNAGRRTILFVDEVHRFNKSQQDAFLPHIEDGTITFIGATTENPSFELNSALLSRARVYLLKSLSTEDIEQVLTQAMEDKTRGYGGQDIVLPDETRRAIAELVNGDARRALNTLEMMADMAEVDDSGKRVLKPELLTEIAGERSARFDNKGDRFYDLISALHKSVRGSAPDAALYWYARIITAGGDPLYVARRCLAIASEDVGNADPRAMQVAIAAWDCFTRVGPAEGERAIAQAIVYLACAPKSNAVYTAFKAALADARERPDYDVPVHLRNAPTKLMKEMGYGQEYRYAHDEANAYAAGEVYFPPEIAQTRYYFPTNRGLEGKIGEKLAWLAEQDQNSPIKRYR
>NC_013654.1|WP_000886683.1|908606_909899_+|serine--tRNA-ligase
MLDPNLLRNEPDAVAEKLARRGFKLDVDKLGALEERRKVLQVKTENLQAERNSRSKSIGQAKARGEDIEPLRLEVNKLGEELDAAKAELDALQAEIRDIALTIPNLPADEVPVGKDENDNVEVSRWGTPREFDFEVRDHVTLGEMHSGLDFAAAVKLTGSRFVVMKGQIARMHRALSQFMLDLHTEQHGYSENYVPYLVNQDTLYGTGQLPKFAGDLFHTRPLEEEADTSNYALIPTAEVPLTNLVRGEIIDEDDLPIKMTAHTPCFRSEAGSYGRDTRGLIRMHQFDKVEMVQIVRPEDSMAALEEMTGHAEKVLQLLGLPYRKIILCTGDMGFGACKTYDLEVWIPAQNTYREISSCSNVWDFQARRMQARCRSKSDKKTRLVHTLNGSGLAVGRTLVAVMENYQQADGRIEVPEVLRPYMNGLEYIG

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NC_013654_1	1.1\|728654\|48\|NC_013654\|CRISPRCasFinder	728654-728701	48	NZ_AP023208	Escherichia coli strain TUM18781 plasmid pMTY18781-3, complete sequence	12111-12158	8	0.833
NC_013654_1	1.1\|728654\|48\|NC_013654\|CRISPRCasFinder	728654-728701	48	LR134125	Klebsiella aerogenes strain NCTC10006 genome assembly, plasmid: 5	424237-424284	8	0.833
NC_013654_1	1.1\|728654\|48\|NC_013654\|CRISPRCasFinder	728654-728701	48	NZ_CP044147	Escherichia coli O157 strain AR-0428 plasmid pAR-0428-2	7391-7438	10	0.792
NC_013654_1	1.1\|728654\|48\|NC_013654\|CRISPRCasFinder	728654-728701	48	CP044351	Escherichia coli strain 194195 plasmid p194195_1, complete sequence	84215-84262	10	0.792
NC_013654_1	1.1\|728654\|48\|NC_013654\|CRISPRCasFinder	728654-728701	48	NZ_AP023206	Escherichia coli strain TUM18781 plasmid pMTY18781-1_lncX3, complete sequence	87125-87172	10	0.792
NC_013654_1	1.1\|728654\|48\|NC_013654\|CRISPRCasFinder	728654-728701	48	NZ_CP053606	Escherichia coli strain NEB_Turbo plasmid F', complete sequence	229237-229284	11	0.771
NC_013654_1	1.1\|728654\|48\|NC_013654\|CRISPRCasFinder	728654-728701	48	NZ_CP053606	Escherichia coli strain NEB_Turbo plasmid F', complete sequence	229338-229385	11	0.771
NC_013654_1	1.1\|728654\|48\|NC_013654\|CRISPRCasFinder	728654-728701	48	NZ_CP053606	Escherichia coli strain NEB_Turbo plasmid F', complete sequence	229439-229486	11	0.771
NC_013654_1	1.1\|728654\|48\|NC_013654\|CRISPRCasFinder	728654-728701	48	NZ_CP053608	Escherichia coli strain NEB5-alpha_F'Iq plasmid F'Iq, complete sequence	239731-239778	11	0.771
NC_013654_1	1.1\|728654\|48\|NC_013654\|CRISPRCasFinder	728654-728701	48	NZ_CP053608	Escherichia coli strain NEB5-alpha_F'Iq plasmid F'Iq, complete sequence	239832-239879	11	0.771
NC_013654_1	1.1\|728654\|48\|NC_013654\|CRISPRCasFinder	728654-728701	48	NZ_CP053608	Escherichia coli strain NEB5-alpha_F'Iq plasmid F'Iq, complete sequence	239933-239980	11	0.771
NC_013654_1	1.1\|728654\|48\|NC_013654\|CRISPRCasFinder	728654-728701	48	NZ_CP044307	Escherichia coli strain C27A plasmid pC27A-2, complete sequence	15006-15053	11	0.771
NC_013654_1	1.1\|728654\|48\|NC_013654\|CRISPRCasFinder	728654-728701	48	NZ_CP014271	Escherichia coli K-12 strain K-12 DHB4 plasmid F128-(DHB4), complete sequence	230643-230690	11	0.771
NC_013654_1	1.1\|728654\|48\|NC_013654\|CRISPRCasFinder	728654-728701	48	NZ_CP014271	Escherichia coli K-12 strain K-12 DHB4 plasmid F128-(DHB4), complete sequence	230744-230791	11	0.771
NC_013654_1	1.1\|728654\|48\|NC_013654\|CRISPRCasFinder	728654-728701	48	NZ_CP014271	Escherichia coli K-12 strain K-12 DHB4 plasmid F128-(DHB4), complete sequence	230845-230892	11	0.771
NC_013654_1	1.1\|728654\|48\|NC_013654\|CRISPRCasFinder	728654-728701	48	NZ_CP014273	Escherichia coli K-12 strain K-12 C3026 plasmid F128-(C3026), complete sequence	211613-211660	11	0.771
NC_013654_1	1.1\|728654\|48\|NC_013654\|CRISPRCasFinder	728654-728701	48	NZ_CP014273	Escherichia coli K-12 strain K-12 C3026 plasmid F128-(C3026), complete sequence	211714-211761	11	0.771
NC_013654_1	1.1\|728654\|48\|NC_013654\|CRISPRCasFinder	728654-728701	48	NZ_CP014273	Escherichia coli K-12 strain K-12 C3026 plasmid F128-(C3026), complete sequence	211815-211862	11	0.771
NC_013654_1	1.1\|728654\|48\|NC_013654\|CRISPRCasFinder	728654-728701	48	NZ_AP023207	Escherichia coli strain TUM18781 plasmid pMTY18781-2, complete sequence	31250-31297	11	0.771
NC_013654_1	1.1\|728654\|48\|NC_013654\|CRISPRCasFinder	728654-728701	48	NZ_CP053606	Escherichia coli strain NEB_Turbo plasmid F', complete sequence	3371-3418	12	0.75
NC_013654_1	1.1\|728654\|48\|NC_013654\|CRISPRCasFinder	728654-728701	48	NZ_CP053606	Escherichia coli strain NEB_Turbo plasmid F', complete sequence	4012-4059	12	0.75
NC_013654_1	1.1\|728654\|48\|NC_013654\|CRISPRCasFinder	728654-728701	48	NZ_CP053606	Escherichia coli strain NEB_Turbo plasmid F', complete sequence	4113-4160	12	0.75
NC_013654_1	1.1\|728654\|48\|NC_013654\|CRISPRCasFinder	728654-728701	48	NZ_CP053606	Escherichia coli strain NEB_Turbo plasmid F', complete sequence	208980-209027	12	0.75
NC_013654_1	1.1\|728654\|48\|NC_013654\|CRISPRCasFinder	728654-728701	48	NZ_CP053608	Escherichia coli strain NEB5-alpha_F'Iq plasmid F'Iq, complete sequence	3370-3417	12	0.75
NC_013654_1	1.1\|728654\|48\|NC_013654\|CRISPRCasFinder	728654-728701	48	NZ_CP053608	Escherichia coli strain NEB5-alpha_F'Iq plasmid F'Iq, complete sequence	4011-4058	12	0.75
NC_013654_1	1.1\|728654\|48\|NC_013654\|CRISPRCasFinder	728654-728701	48	NZ_CP053608	Escherichia coli strain NEB5-alpha_F'Iq plasmid F'Iq, complete sequence	4112-4159	12	0.75
NC_013654_1	1.1\|728654\|48\|NC_013654\|CRISPRCasFinder	728654-728701	48	NZ_CP053608	Escherichia coli strain NEB5-alpha_F'Iq plasmid F'Iq, complete sequence	219474-219521	12	0.75
NC_013654_1	1.1\|728654\|48\|NC_013654\|CRISPRCasFinder	728654-728701	48	NZ_CP014271	Escherichia coli K-12 strain K-12 DHB4 plasmid F128-(DHB4), complete sequence	3370-3417	12	0.75
NC_013654_1	1.1\|728654\|48\|NC_013654\|CRISPRCasFinder	728654-728701	48	NZ_CP014271	Escherichia coli K-12 strain K-12 DHB4 plasmid F128-(DHB4), complete sequence	4011-4058	12	0.75
NC_013654_1	1.1\|728654\|48\|NC_013654\|CRISPRCasFinder	728654-728701	48	NZ_CP014271	Escherichia coli K-12 strain K-12 DHB4 plasmid F128-(DHB4), complete sequence	4112-4159	12	0.75
NC_013654_1	1.1\|728654\|48\|NC_013654\|CRISPRCasFinder	728654-728701	48	NZ_CP014271	Escherichia coli K-12 strain K-12 DHB4 plasmid F128-(DHB4), complete sequence	210308-210355	12	0.75
NC_013654_1	1.1\|728654\|48\|NC_013654\|CRISPRCasFinder	728654-728701	48	NZ_CP014273	Escherichia coli K-12 strain K-12 C3026 plasmid F128-(C3026), complete sequence	3370-3417	12	0.75
NC_013654_1	1.1\|728654\|48\|NC_013654\|CRISPRCasFinder	728654-728701	48	NZ_CP014273	Escherichia coli K-12 strain K-12 C3026 plasmid F128-(C3026), complete sequence	4011-4058	12	0.75
NC_013654_1	1.1\|728654\|48\|NC_013654\|CRISPRCasFinder	728654-728701	48	NZ_CP014273	Escherichia coli K-12 strain K-12 C3026 plasmid F128-(C3026), complete sequence	4112-4159	12	0.75
NC_013654_1	1.1\|728654\|48\|NC_013654\|CRISPRCasFinder	728654-728701	48	NZ_CP014273	Escherichia coli K-12 strain K-12 C3026 plasmid F128-(C3026), complete sequence	191263-191310	12	0.75
NC_013654_1	1.1\|728654\|48\|NC_013654\|CRISPRCasFinder	728654-728701	48	MT230402	Escherichia coli strain DH5alpha plasmid pESBL87, complete sequence	270-317	12	0.75
NC_013654_1	1.1\|728654\|48\|NC_013654\|CRISPRCasFinder	728654-728701	48	NZ_AP023206	Escherichia coli strain TUM18781 plasmid pMTY18781-1_lncX3, complete sequence	101195-101242	12	0.75
NC_013654_1	1.1\|728654\|48\|NC_013654\|CRISPRCasFinder	728654-728701	48	MT230312	Escherichia coli strain DH5alpha plasmid pESBL31, complete sequence	158-205	13	0.729

1. spacer 1.1|728654|48|NC_013654|CRISPRCasFinder matches to NZ_AP023208 (Escherichia coli strain TUM18781 plasmid pMTY18781-3, complete sequence) position: , mismatch: 8, identity: 0.833

aaaccgtaggcctgataagacgcgcaagcgtcgcatcaggcaaacagc	CRISPR spacer
gactcgtaggcctgataagacgcgccagcgtcgcatcaggcaccgaac	Protospacer
.* .********************* ****************   *.*

2. spacer 1.1|728654|48|NC_013654|CRISPRCasFinder matches to LR134125 (Klebsiella aerogenes strain NCTC10006 genome assembly, plasmid: 5) position: , mismatch: 8, identity: 0.833

aaaccgtaggcctgataagacgcgcaagcgtcg-catcaggcaaacagc	CRISPR spacer
aacctgtaggcctgataagacgcgcaagcgtcgccatcaggcatctca-	Protospacer
** *.**************************** *********  . .

3. spacer 1.1|728654|48|NC_013654|CRISPRCasFinder matches to NZ_CP044147 (Escherichia coli O157 strain AR-0428 plasmid pAR-0428-2) position: , mismatch: 10, identity: 0.792

aaaccgtaggcctgataagacgcgcaagcgtcgcatcaggcaaacagc	CRISPR spacer
gttttgtaggcatgataagacgcgccagcgtcgcatcaggcatccggc	Protospacer
.  ..****** ************* ****************  *.**

4. spacer 1.1|728654|48|NC_013654|CRISPRCasFinder matches to CP044351 (Escherichia coli strain 194195 plasmid p194195_1, complete sequence) position: , mismatch: 10, identity: 0.792

aaaccgtaggcctgataagacgcgcaagcgtcgcatcaggcaaacagc	CRISPR spacer
gttttgtaggcatgataagacgcgccagcgtcgcatcaggcatccggc	Protospacer
.  ..****** ************* ****************  *.**

5. spacer 1.1|728654|48|NC_013654|CRISPRCasFinder matches to NZ_AP023206 (Escherichia coli strain TUM18781 plasmid pMTY18781-1_lncX3, complete sequence) position: , mismatch: 10, identity: 0.792

aaaccgtaggcctgataagacgcgcaagcgtcgcatcaggcaaacagc	CRISPR spacer
attttgtaggcctgataagacgcggcagcgtcgcatcaggcatcgtgc	Protospacer
*  ..*******************  ****************    **

6. spacer 1.1|728654|48|NC_013654|CRISPRCasFinder matches to NZ_CP053606 (Escherichia coli strain NEB_Turbo plasmid F', complete sequence) position: , mismatch: 11, identity: 0.771

aaaccgtaggcctgataagacgcgcaagcgtcgcatcaggcaaacagc	CRISPR spacer
aatttgtaggcctgataagacgcgttagcgtcgcatcaggcatctgcg	Protospacer
** ..*******************. ****************  ..

7. spacer 1.1|728654|48|NC_013654|CRISPRCasFinder matches to NZ_CP053606 (Escherichia coli strain NEB_Turbo plasmid F', complete sequence) position: , mismatch: 11, identity: 0.771

aaaccgtaggcctgataagacgcgcaagcgtcgcatcaggcaaacagc	CRISPR spacer
aatttgtaggcctgataagacgcgttagcgtcgcatcaggcatctgcg	Protospacer
** ..*******************. ****************  ..

8. spacer 1.1|728654|48|NC_013654|CRISPRCasFinder matches to NZ_CP053606 (Escherichia coli strain NEB_Turbo plasmid F', complete sequence) position: , mismatch: 11, identity: 0.771

aaaccgtaggcctgataagacgcgcaagcgtcgcatcaggcaaacagc	CRISPR spacer
aatttgtaggcctgataagacgcgttagcgtcgcatcaggcatctgca	Protospacer
** ..*******************. ****************  ..

9. spacer 1.1|728654|48|NC_013654|CRISPRCasFinder matches to NZ_CP053608 (Escherichia coli strain NEB5-alpha_F'Iq plasmid F'Iq, complete sequence) position: , mismatch: 11, identity: 0.771

aaaccgtaggcctgataagacgcgcaagcgtcgcatcaggcaaacagc	CRISPR spacer
aatttgtaggcctgataagacgcgttagcgtcgcatcaggcatctgcg	Protospacer
** ..*******************. ****************  ..

10. spacer 1.1|728654|48|NC_013654|CRISPRCasFinder matches to NZ_CP053608 (Escherichia coli strain NEB5-alpha_F'Iq plasmid F'Iq, complete sequence) position: , mismatch: 11, identity: 0.771

aaaccgtaggcctgataagacgcgcaagcgtcgcatcaggcaaacagc	CRISPR spacer
aatttgtaggcctgataagacgcgttagcgtcgcatcaggcatctgcg	Protospacer
** ..*******************. ****************  ..

11. spacer 1.1|728654|48|NC_013654|CRISPRCasFinder matches to NZ_CP053608 (Escherichia coli strain NEB5-alpha_F'Iq plasmid F'Iq, complete sequence) position: , mismatch: 11, identity: 0.771

aaaccgtaggcctgataagacgcgcaagcgtcgcatcaggcaaacagc	CRISPR spacer
aatttgtaggcctgataagacgcgttagcgtcgcatcaggcatctgca	Protospacer
** ..*******************. ****************  ..

12. spacer 1.1|728654|48|NC_013654|CRISPRCasFinder matches to NZ_CP044307 (Escherichia coli strain C27A plasmid pC27A-2, complete sequence) position: , mismatch: 11, identity: 0.771

aaaccgtaggcctgataagacgcgcaagcgtcgcatcaggcaaacagc	CRISPR spacer
ggctcgtaggcatgataagacgcgccagcgtcgcatcaggcacctggt	Protospacer
.. .******* ************* ****************  ..*.

13. spacer 1.1|728654|48|NC_013654|CRISPRCasFinder matches to NZ_CP014271 (Escherichia coli K-12 strain K-12 DHB4 plasmid F128-(DHB4), complete sequence) position: , mismatch: 11, identity: 0.771

aaaccgtaggcctgataagacgcgcaagcgtcgcatcaggcaaacagc	CRISPR spacer
aatttgtaggcctgataagacgcgttagcgtcgcatcaggcatctgcg	Protospacer
** ..*******************. ****************  ..

14. spacer 1.1|728654|48|NC_013654|CRISPRCasFinder matches to NZ_CP014271 (Escherichia coli K-12 strain K-12 DHB4 plasmid F128-(DHB4), complete sequence) position: , mismatch: 11, identity: 0.771

aaaccgtaggcctgataagacgcgcaagcgtcgcatcaggcaaacagc	CRISPR spacer
aatttgtaggcctgataagacgcgttagcgtcgcatcaggcatctgcg	Protospacer
** ..*******************. ****************  ..

15. spacer 1.1|728654|48|NC_013654|CRISPRCasFinder matches to NZ_CP014271 (Escherichia coli K-12 strain K-12 DHB4 plasmid F128-(DHB4), complete sequence) position: , mismatch: 11, identity: 0.771

aaaccgtaggcctgataagacgcgcaagcgtcgcatcaggcaaacagc	CRISPR spacer
aatttgtaggcctgataagacgcgttagcgtcgcatcaggcatctgca	Protospacer
** ..*******************. ****************  ..

16. spacer 1.1|728654|48|NC_013654|CRISPRCasFinder matches to NZ_CP014273 (Escherichia coli K-12 strain K-12 C3026 plasmid F128-(C3026), complete sequence) position: , mismatch: 11, identity: 0.771

aaaccgtaggcctgataagacgcgcaagcgtcgcatcaggcaaacagc	CRISPR spacer
aatttgtaggcctgataagacgcgttagcgtcgcatcaggcatctgcg	Protospacer
** ..*******************. ****************  ..

17. spacer 1.1|728654|48|NC_013654|CRISPRCasFinder matches to NZ_CP014273 (Escherichia coli K-12 strain K-12 C3026 plasmid F128-(C3026), complete sequence) position: , mismatch: 11, identity: 0.771

aaaccgtaggcctgataagacgcgcaagcgtcgcatcaggcaaacagc	CRISPR spacer
aatttgtaggcctgataagacgcgttagcgtcgcatcaggcatctgcg	Protospacer
** ..*******************. ****************  ..

18. spacer 1.1|728654|48|NC_013654|CRISPRCasFinder matches to NZ_CP014273 (Escherichia coli K-12 strain K-12 C3026 plasmid F128-(C3026), complete sequence) position: , mismatch: 11, identity: 0.771

aaaccgtaggcctgataagacgcgcaagcgtcgcatcaggcaaacagc	CRISPR spacer
aatttgtaggcctgataagacgcgttagcgtcgcatcaggcatctgca	Protospacer
** ..*******************. ****************  ..

19. spacer 1.1|728654|48|NC_013654|CRISPRCasFinder matches to NZ_AP023207 (Escherichia coli strain TUM18781 plasmid pMTY18781-2, complete sequence) position: , mismatch: 11, identity: 0.771

aaaccgtaggcctgataagacgcgcaagcgtcgcatcaggcaaacagc	CRISPR spacer
cggctgtaggcctgataagacgcgacagcgtcgcatcaggcattgatt	Protospacer
 ..*.*******************  ****************   * .

20. spacer 1.1|728654|48|NC_013654|CRISPRCasFinder matches to NZ_CP053606 (Escherichia coli strain NEB_Turbo plasmid F', complete sequence) position: , mismatch: 12, identity: 0.75

aaaccgtaggcctgataagacgcgcaagcgtcgcatcaggcaaacagc	CRISPR spacer
ggctcgtaggcatgataagacgcgccagcgtcgcatcaggcacctgcg	Protospacer
.. .******* ************* ****************  ..

21. spacer 1.1|728654|48|NC_013654|CRISPRCasFinder matches to NZ_CP053606 (Escherichia coli strain NEB_Turbo plasmid F', complete sequence) position: , mismatch: 12, identity: 0.75

aaaccgtaggcctgataagacgcgcaagcgtcgcatcaggcaaacagc	CRISPR spacer
agtttgtaggcatgataagacgcgctagcgtcgcatcaggcatctgcg	Protospacer
*. ..****** ************* ****************  ..

22. spacer 1.1|728654|48|NC_013654|CRISPRCasFinder matches to NZ_CP053606 (Escherichia coli strain NEB_Turbo plasmid F', complete sequence) position: , mismatch: 12, identity: 0.75

aaaccgtaggcctgataagacgcgcaagcgtcgcatcaggcaaacagc	CRISPR spacer
agtttgtaggcatgataagacgcgccagcgtcgcatcaggcatctgcg	Protospacer
*. ..****** ************* ****************  ..

23. spacer 1.1|728654|48|NC_013654|CRISPRCasFinder matches to NZ_CP053606 (Escherichia coli strain NEB_Turbo plasmid F', complete sequence) position: , mismatch: 12, identity: 0.75

aaaccgtaggcctgataagacgcgcaagcgtcgcatcaggcaaacagc	CRISPR spacer
agtgggtaggcctgataagacgcgtcagcgtcgcatcaggcatctgag	Protospacer
*.   *******************. ****************  ...

24. spacer 1.1|728654|48|NC_013654|CRISPRCasFinder matches to NZ_CP053608 (Escherichia coli strain NEB5-alpha_F'Iq plasmid F'Iq, complete sequence) position: , mismatch: 12, identity: 0.75

aaaccgtaggcctgataagacgcgcaagcgtcgcatcaggcaaacagc	CRISPR spacer
ggctcgtaggcatgataagacgcgccagcgtcgcatcaggcacctgcg	Protospacer
.. .******* ************* ****************  ..

25. spacer 1.1|728654|48|NC_013654|CRISPRCasFinder matches to NZ_CP053608 (Escherichia coli strain NEB5-alpha_F'Iq plasmid F'Iq, complete sequence) position: , mismatch: 12, identity: 0.75

aaaccgtaggcctgataagacgcgcaagcgtcgcatcaggcaaacagc	CRISPR spacer
agtttgtaggcatgataagacgcgctagcgtcgcatcaggcatctgcg	Protospacer
*. ..****** ************* ****************  ..

26. spacer 1.1|728654|48|NC_013654|CRISPRCasFinder matches to NZ_CP053608 (Escherichia coli strain NEB5-alpha_F'Iq plasmid F'Iq, complete sequence) position: , mismatch: 12, identity: 0.75

aaaccgtaggcctgataagacgcgcaagcgtcgcatcaggcaaacagc	CRISPR spacer
agtttgtaggcatgataagacgcgccagcgtcgcatcaggcatctgcg	Protospacer
*. ..****** ************* ****************  ..

27. spacer 1.1|728654|48|NC_013654|CRISPRCasFinder matches to NZ_CP053608 (Escherichia coli strain NEB5-alpha_F'Iq plasmid F'Iq, complete sequence) position: , mismatch: 12, identity: 0.75

aaaccgtaggcctgataagacgcgcaagcgtcgcatcaggcaaacagc	CRISPR spacer
agtgggtaggcctgataagacgcgtcagcgtcgcatcaggcatctgag	Protospacer
*.   *******************. ****************  ...

28. spacer 1.1|728654|48|NC_013654|CRISPRCasFinder matches to NZ_CP014271 (Escherichia coli K-12 strain K-12 DHB4 plasmid F128-(DHB4), complete sequence) position: , mismatch: 12, identity: 0.75

aaaccgtaggcctgataagacgcgcaagcgtcgcatcaggcaaacagc	CRISPR spacer
ggctcgtaggcatgataagacgcgccagcgtcgcatcaggcacctgcg	Protospacer
.. .******* ************* ****************  ..

29. spacer 1.1|728654|48|NC_013654|CRISPRCasFinder matches to NZ_CP014271 (Escherichia coli K-12 strain K-12 DHB4 plasmid F128-(DHB4), complete sequence) position: , mismatch: 12, identity: 0.75

aaaccgtaggcctgataagacgcgcaagcgtcgcatcaggcaaacagc	CRISPR spacer
agtttgtaggcatgataagacgcgctagcgtcgcatcaggcatctgcg	Protospacer
*. ..****** ************* ****************  ..

30. spacer 1.1|728654|48|NC_013654|CRISPRCasFinder matches to NZ_CP014271 (Escherichia coli K-12 strain K-12 DHB4 plasmid F128-(DHB4), complete sequence) position: , mismatch: 12, identity: 0.75

aaaccgtaggcctgataagacgcgcaagcgtcgcatcaggcaaacagc	CRISPR spacer
agtttgtaggcatgataagacgcgccagcgtcgcatcaggcatctgcg	Protospacer
*. ..****** ************* ****************  ..

31. spacer 1.1|728654|48|NC_013654|CRISPRCasFinder matches to NZ_CP014271 (Escherichia coli K-12 strain K-12 DHB4 plasmid F128-(DHB4), complete sequence) position: , mismatch: 12, identity: 0.75

aaaccgtaggcctgataagacgcgcaagcgtcgcatcaggcaaacagc	CRISPR spacer
agtgggtaggcctgataagacgcgtcagcgtcgcatcaggcatctgag	Protospacer
*.   *******************. ****************  ...

32. spacer 1.1|728654|48|NC_013654|CRISPRCasFinder matches to NZ_CP014273 (Escherichia coli K-12 strain K-12 C3026 plasmid F128-(C3026), complete sequence) position: , mismatch: 12, identity: 0.75

aaaccgtaggcctgataagacgcgcaagcgtcgcatcaggcaaacagc	CRISPR spacer
ggctcgtaggcatgataagacgcgccagcgtcgcatcaggcacctgcg	Protospacer
.. .******* ************* ****************  ..

33. spacer 1.1|728654|48|NC_013654|CRISPRCasFinder matches to NZ_CP014273 (Escherichia coli K-12 strain K-12 C3026 plasmid F128-(C3026), complete sequence) position: , mismatch: 12, identity: 0.75

aaaccgtaggcctgataagacgcgcaagcgtcgcatcaggcaaacagc	CRISPR spacer
agtttgtaggcatgataagacgcgctagcgtcgcatcaggcatctgcg	Protospacer
*. ..****** ************* ****************  ..

34. spacer 1.1|728654|48|NC_013654|CRISPRCasFinder matches to NZ_CP014273 (Escherichia coli K-12 strain K-12 C3026 plasmid F128-(C3026), complete sequence) position: , mismatch: 12, identity: 0.75

aaaccgtaggcctgataagacgcgcaagcgtcgcatcaggcaaacagc	CRISPR spacer
agtttgtaggcatgataagacgcgccagcgtcgcatcaggcatctgcg	Protospacer
*. ..****** ************* ****************  ..

35. spacer 1.1|728654|48|NC_013654|CRISPRCasFinder matches to NZ_CP014273 (Escherichia coli K-12 strain K-12 C3026 plasmid F128-(C3026), complete sequence) position: , mismatch: 12, identity: 0.75

aaaccgtaggcctgataagacgcgcaagcgtcgcatcaggcaaacagc	CRISPR spacer
agtgggtaggcctgataagacgcgtcagcgtcgcatcaggcatctgag	Protospacer
*.   *******************. ****************  ...

36. spacer 1.1|728654|48|NC_013654|CRISPRCasFinder matches to MT230402 (Escherichia coli strain DH5alpha plasmid pESBL87, complete sequence) position: , mismatch: 12, identity: 0.75

aaaccgtaggcctgataagacgcgcaagcgtcgcatcaggcaaacagc	CRISPR spacer
ggtttgtaggcctgataagacgcgacagcgtcgcatcaggcattgatt	Protospacer
.. ..*******************  ****************   * .

37. spacer 1.1|728654|48|NC_013654|CRISPRCasFinder matches to NZ_AP023206 (Escherichia coli strain TUM18781 plasmid pMTY18781-1_lncX3, complete sequence) position: , mismatch: 12, identity: 0.75

aaaccgtaggcctgataagacgcgcaagcgtcgcatcaggcaaacagc	CRISPR spacer
taatacaaggcctgataagacgcgccagcgtcgcatcaggcgctgaat	Protospacer
 **.   ****************** ***************.   *..

38. spacer 1.1|728654|48|NC_013654|CRISPRCasFinder matches to MT230312 (Escherichia coli strain DH5alpha plasmid pESBL31, complete sequence) position: , mismatch: 13, identity: 0.729

aaaccgtaggcctgataagacgcgcaagcgtcgcatcaggcaaacagc	CRISPR spacer
gtctngtaggcctgataagacgcgtcagcgtcgcatcaggcttcaatt	Protospacer
.  . *******************. ***************    * .

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

1137396 : 1190863

Enterobacteria_phage(55.17%)

tail,lysis,portal,capsid,transposase,terminase,integrase,head,tRNA

attL 1130032:1130047|attR 1194724:1194739

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
1130032:1130047	attL	NA	NA	NA	NA
WP_001295972.1\|1137396_1138503_-\|tRNA	tRNA 2-thiouridine(34) synthase MnmA	NA	NA	NA	NA
WP_000476093.1\|1138556_1139018_-	phosphatase NudJ	NA	NA	NA	NA
WP_001248677.1\|1139027_1139681_-	23S rRNA pseudouridine(2457) synthase RluE	NA	NA	NA	NA
WP_000444487.1\|1139852_1141103_+	NADP-dependent isocitrate dehydrogenase	Q77Z09	Phage_21	3.8e-23	100.0
WP_000741335.1\|1141216_1142359_-\|integrase	phage integrase Arm DNA-binding domain-containing protein	Q77Z02	Phage_21	3.6e-206	100.0
WP_000088653.1\|1142348_1142585_-	excisionase	NA	NA	NA	NA
WP_000488406.1\|1142724_1142964_-	DUF4222 domain-containing protein	M1FPC8	Enterobacteria_phage	3.9e-38	94.9
WP_000763364.1\|1143011_1143230_-	TraR/DksA family transcriptional regulator	M1FQT7	Enterobacteria_phage	1.8e-34	95.8
WP_001308571.1\|1143328_1143610_-	hypothetical protein	A0A0P0ZE02	Stx2-converting_phage	1.2e-46	97.8
WP_000548537.1\|1143620_1143812_-	DUF1382 family protein	A0A0P0ZC67	Stx2-converting_phage	2.1e-26	98.4
WP_000149539.1\|1143784_1143967_-	DUF1317 domain-containing protein	A0A0N7CHV0	Escherichia_phage	6.3e-28	96.7
WP_000186858.1\|1143963_1144644_-	YqaJ viral recombinase family protein	A0A0P0ZCD4	Stx2-converting_phage	4.6e-132	99.6
WP_000100847.1\|1144640_1145426_-	phage recombination protein Bet	A0A1I9LJN0	Stx_converting_phage	6.3e-149	100.0
WP_000995417.1\|1145431_1145728_-	host-nuclease inhibitor protein Gam	A0A1I9LJN1	Stx_converting_phage	1.5e-47	96.9
WP_000233576.1\|1145803_1146010_-	phage encoded cell division inhibitor protein	K7P6H3	Enterobacteria_phage	3.2e-28	85.3
WP_000866321.1\|1146485_1146863_-	ASCH domain-containing protein	Q6SE87	Lactobacillus_prophage	1.3e-30	49.2
WP_000380252.1\|1146840_1147902_-	hypothetical protein	Q6SE88	Lactobacillus_prophage	2.9e-64	42.0
WP_000712396.1\|1147982_1148675_-	helix-turn-helix transcriptional regulator	Q76H56	Enterobacteria_phage	2.5e-109	85.3
WP_000184665.1\|1148785_1149013_+	helix-turn-helix domain-containing protein	Q76H55	Enterobacteria_phage	3.8e-22	69.0
WP_001182881.1\|1149043_1149583_+	hypothetical protein	M9NZI6	Enterobacteria_phage	8.9e-62	66.7
WP_000147914.1\|1149579_1150599_+	replication protein	A0A0M5M7Y1	Salmonella_phage	2.7e-112	64.7
WP_000788877.1\|1150595_1151297_+	Replication protein 14	K7P6G2	Enterobacteria_phage	9.9e-130	100.0
WP_000145918.1\|1151293_1151596_+	protein ren	A0A0N6WES4	Escherichia_phage	1.3e-41	93.5
WP_001070442.1\|1151663_1151996_+	SMR family multidrug efflux protein EmrE	NA	NA	NA	NA
WP_032143398.1\|1152044_1152194_+	hypothetical protein	NA	NA	NA	NA
WP_000709098.1\|1152251_1153778_+	recombinase family protein	Q3HQV4	Burkholderia_phage	2.7e-31	30.8
WP_000700204.1\|1154127_1155171_-	alpha/beta hydrolase	NA	NA	NA	NA
WP_072093903.1\|1155520_1155622_+	hypothetical protein	NA	NA	NA	NA
WP_001053004.1\|1155618_1156074_+	DNA base-flipping protein YbcN	I6PD71	Cronobacter_phage	1.2e-59	66.9
WP_000224907.1\|1156073_1156244_+	hypothetical protein	K7P7K0	Enterobacteria_phage	5.3e-13	67.9
WP_000774475.1\|1156236_1156527_+	DUF1364 domain-containing protein	K7PGZ6	Enterobacteria_phage	1.3e-46	93.8
WP_001099697.1\|1156523_1156886_+	crossover junction endodeoxyribonuclease RusA	K7PM48	Enterobacteria_phage	7.3e-60	95.7
WP_000971095.1\|1156882_1157023_+	YlcG family protein	K7PHH3	Enterobacteria_phage	1.7e-09	72.1
WP_001204794.1\|1157108_1157492_+	antitermination protein QuuD	A0A088CD47	Shigella_phage	2.0e-55	82.5
WP_000737277.1\|1157680_1158763_-	porin OmpC	Q1MVN1	Enterobacteria_phage	4.1e-167	79.0
WP_000839596.1\|1159352_1159568_+\|lysis	phage lysis protein EssD	A5LH82	Enterobacteria_phage	9.0e-34	100.0
WP_000075094.1\|1159567_1160065_+	lysozyme RrrD	A5LH83	Enterobacteria_phage	1.7e-91	99.4
WP_001441931.1\|1160061_1160505_+\|lysis	lysis protein	M1FJ79	Enterobacteria_phage	4.3e-70	92.5
WP_000084844.1\|1160543_1160918_+	hypothetical protein	M1FPD9	Enterobacteria_phage	1.5e-47	80.6
WP_012896773.1\|1161149_1161428_+	hypothetical protein	K7PJR7	Enterobacteria_phage	1.3e-08	87.5
WP_000867568.1\|1161509_1162058_+\|terminase	terminase small subunit	A0A0U2S671	Escherichia_phage	1.0e-57	84.2
WP_001573719.1\|1162029_1163958_+\|terminase	phage terminase large subunit family protein	A0A0K2FJ14	Enterobacteria_phage	1.1e-260	66.9
WP_000258997.1\|1163941_1164148_+\|head	phage head-stabilizing protein	K7PM10	Enterobacteria_phage	3.0e-10	55.4
WP_001441934.1\|1164144_1165737_+\|portal	phage portal protein	K7P6U7	Enterobacteria_phage	4.2e-184	60.9
WP_001253893.1\|1165726_1167232_+	S49 family peptidase	A0A0K2FI53	Enterobacteria_phage	7.9e-100	53.5
WP_000256813.1\|1167268_1167616_+\|head	head decoration protein	A0A2R9YJN3	Escherichia_phage	2.6e-22	58.1
WP_000522650.1\|1167673_1168702_+\|capsid	major capsid protein	C6ZCY2	Enterobacteria_phage	4.5e-115	61.6
WP_000201530.1\|1168753_1169128_+	hypothetical protein	NA	NA	NA	NA
WP_001204540.1\|1169120_1169474_+\|tail	tail attachment protein	A0A0K2FJB7	Enterobacteria_phage	3.4e-38	65.0
WP_001007370.1\|1169485_1170064_+\|tail	phage tail protein	A0A2R9YJK4	Escherichia_phage	1.1e-78	91.7
WP_000683150.1\|1170060_1170456_+\|tail	tail protein	A0A2R9YJI2	Escherichia_phage	2.9e-70	98.5
WP_001545921.1\|1170463_1171204_+\|tail	phage tail protein	A0A2I6TC77	Escherichia_phage	2.8e-130	98.0
WP_000479204.1\|1171219_1171642_+\|tail	phage minor tail protein G	A0A0K2FIQ8	Enterobacteria_phage	3.7e-71	97.9
WP_000459449.1\|1171623_1172058_+\|tail	phage tail assembly protein T	A0A0K2FJB3	Enterobacteria_phage	3.8e-63	98.3
WP_000840282.1\|1172050_1174612_+\|tail	phage tail tape measure protein	A0A2R9YJM8	Escherichia_phage	0.0e+00	88.8
WP_000847387.1\|1174608_1174938_+\|tail	phage tail protein	A0A2R9YJM0	Escherichia_phage	9.9e-56	94.5
WP_001152542.1\|1174937_1175636_+\|tail	phage minor tail protein L	A0A0K2FJ01	Enterobacteria_phage	5.2e-131	97.8
WP_000194748.1\|1175641_1176385_+\|tail	phage tail protein	K7PLW1	Enterobacteria_phage	3.3e-147	96.8
WP_000090860.1\|1176321_1176954_+\|tail	tail assembly protein	C6ZCZ4	Enterobacteria_phage	4.6e-94	97.6
WP_001298859.1\|1177561_1179103_+\|transposase	IS21-like element ISEc12 family transposase	K4I413	Acidithiobacillus_phage	1.7e-129	46.4
WP_001016257.1\|1179117_1179864_+	ATP-binding protein	U5N3V8	Enterobacteria_phage	3.5e-24	31.6
WP_001545960.1\|1183057_1184986_+\|tail	prophage tail fiber N-terminal domain-containing protein	A0A0E3M194	Enterobacteria_phage	7.5e-111	60.1
WP_000422741.1\|1185067_1185493_+	IS66 family insertion sequence hypothetical protein	Q6H9S5	Enterobacteria_phage	1.5e-48	99.0
WP_000624722.1\|1185489_1185840_+	IS66 family insertion sequence element accessory protein TnpB	A0A0P0ZBY2	Stx2-converting_phage	4.7e-40	66.4
WP_000080195.1\|1185870_1187484_+\|transposase	IS66-like element ISEc23 family transposase	A0A0P0ZEB3	Stx2-converting_phage	3.0e-182	63.6
WP_000654168.1\|1187651_1187930_+	hypothetical protein	A0A0E3JSQ1	Enterobacteria_phage	7.6e-25	57.6
WP_000355360.1\|1187942_1188236_+	hypothetical protein	NA	NA	NA	NA
WP_000968127.1\|1188327_1189185_-	iron/manganese ABC transporter permease subunit SitD	NA	NA	NA	NA
WP_001101733.1\|1189181_1190039_-	iron/manganese ABC transporter permease subunit SitC	NA	NA	NA	NA
WP_000983701.1\|1190035_1190863_-	iron/manganese ABC transporter ATP-binding protein SitB	M1HV27	Acanthocystis_turfacea_Chlorella_virus	8.7e-08	27.7
1194724:1194739	attR	NA	NA	NA	NA

DBSCAN-SWA_2

2056139 : 2064810

Escherichia_phage(28.57%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000272486.1\|2056139_2057243_-	UDP-galactopyranose mutase	E4ZFQ1	Streptococcus_phage	1.0e-133	59.5
WP_001393538.1\|2057250_2058498_-	O16 family O-antigen flippase	NA	NA	NA	NA
WP_001100981.1\|2058494_2059052_-	dTDP-4-dehydrorhamnose 3,5-epimerase	A0A291LA62	Escherichia_phage	7.8e-53	57.5
WP_000783975.1\|2059051_2059933_-	glucose-1-phosphate thymidylyltransferase RfbA	I7I009	Enterobacteria_phage	1.9e-106	63.8
WP_001023617.1\|2059990_2060890_-	dTDP-4-dehydrorhamnose reductase	A0A291LA50	Escherichia_phage	6.3e-28	34.5
WP_000699450.1\|2060889_2061975_-	dTDP-glucose 4,6-dehydratase	I7HTA3	Enterobacteria_phage	3.9e-101	53.9
WP_000183060.1\|2062347_2063241_-	UTP--glucose-1-phosphate uridylyltransferase GalF	A0A127AW70	Bacillus_phage	1.0e-46	42.0
WP_001115960.1\|2063415_2064810_-	colanic acid biosynthesis protein WcaM	A0A291LBB9	Klebsiella_phage	6.3e-19	31.9

DBSCAN-SWA_3

2160848 : 2169160

Enterobacteria_phage(83.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_001296230.1\|2160848_2162852_+	SWIM zinc finger family protein	Q9EYF6	Enterobacteria_phage	0.0e+00	95.7
WP_001296231.1\|2162976_2163438_+	YehR family lipoprotein	Q9EYF5	Enterobacteria_phage	3.2e-76	99.3
WP_001295430.1\|2163478_2163949_-	DUF1456 family protein	Q9EYF4	Enterobacteria_phage	1.8e-82	100.0
WP_000598641.1\|2163995_2164715_-	two-component system response regulator BtsR	NA	NA	NA	NA
WP_001295431.1\|2164711_2166397_-	two-component regulatory system sensor histidine kinase BtsS	Q9EYF3	Enterobacteria_phage	2.5e-304	99.6
WP_001240408.1\|2166618_2167350_+	HTH-type transcriptional regulator MlrA	Q9EYF2	Enterobacteria_phage	6.3e-111	98.5
WP_001216963.1\|2167409_2167517_+	protein YohO	NA	NA	NA	NA
WP_000783109.1\|2167497_2168229_-	glycine betaine ABC transporter permease YehW	NA	NA	NA	NA
WP_000569347.1\|2168233_2169160_-	glycine betaine ABC transporter ATP binding protein YehX	F2Y1V5	Organic_Lake_phycodnavirus	2.6e-08	26.8

DBSCAN-SWA_4

2748332 : 2755472

Escherichia_phage(83.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000103863.1\|2748332_2750894_+	DNA mismatch repair protein MutS	E3T5Q7	Cafeteria_roenbergensis_virus	1.6e-31	20.8
WP_001141293.1\|2750999_2751656_+	protein-serine/threonine phosphatase	A0A077SLQ6	Escherichia_phage	3.3e-50	46.1
WP_001296319.1\|2751706_2752474_-	DeoR/GlpR transcriptional regulator	A0A077SK06	Escherichia_phage	9.7e-70	57.4
WP_000847996.1\|2752669_2753578_+	NAD(P)-dependent oxidoreductase	A0A077SLF7	Escherichia_phage	1.9e-117	76.2
WP_000590411.1\|2753574_2754837_+	3-oxo-tetronate kinase	A0A077SLJ7	Escherichia_phage	2.2e-135	61.4
WP_001279004.1\|2754833_2755472_+	aldolase	A0A077SK32	Escherichia_phage	1.4e-82	74.5

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

2. NC_013655

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

33297 : 81061

Stx2-converting_phage(23.08%)

transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000080195.1\|33297_34911_+\|transposase	IS66-like element ISEc23 family transposase	A0A0P0ZEB3	Stx2-converting_phage	3.0e-182	63.6
WP_000948349.1\|36966_42237_+	conjugative transfer relaxase/helicase TraI	NA	NA	NA	NA
WP_000205725.1\|42256_43003_+	conjugal transfer pilus acetylase TraX	A0A077JBM8	Xanthomonas_phage	2.4e-09	30.8
WP_000704523.1\|43061_43922_+	alpha/beta hydrolase	A2RQC8	Archaeal_BJ1_virus	1.9e-10	23.5
WP_000139321.1\|44024_44585_+	fertility inhibition protein FinO	NA	NA	NA	NA
WP_001309245.1\|44713_44926_+	ANR family transcriptional regulator	NA	NA	NA	NA
WP_001233838.1\|45170_45632_+	thermonuclease family protein	A0A0R6PHV6	Moraxella_phage	4.2e-20	37.1
WP_001298565.1\|45677_45887_+	hemolysin expression modulator Hha	NA	NA	NA	NA
WP_000766808.1\|45924_46515_+	DUF2726 domain-containing protein	NA	NA	NA	NA
WP_001016257.1\|46722_47469_-	ATP-binding protein	K4HZD4	Acidithiobacillus_phage	5.0e-55	48.5
WP_001298859.1\|47483_49025_-\|transposase	IS21-like element ISEc12 family transposase	K4I413	Acidithiobacillus_phage	1.7e-129	46.4
WP_000080195.1\|49268_50882_-\|transposase	IS66-like element ISEc23 family transposase	A0A0P0ZEB3	Stx2-converting_phage	3.0e-182	63.6
WP_000624722.1\|50912_51263_-	IS66 family insertion sequence element accessory protein TnpB	A0A0P0ZBY2	Stx2-converting_phage	4.7e-40	66.4
WP_000422741.1\|51259_51685_-	IS66 family insertion sequence hypothetical protein	Q6H9S5	Enterobacteria_phage	1.5e-48	99.0
WP_000078109.1\|51880_52141_+	replication regulatory protein RepA	NA	NA	NA	NA
WP_001365705.1\|52373_52448_+	RepA leader peptide Tap	NA	NA	NA	NA
WP_000131004.1\|52440_53298_+	incFII family plasmid replication initiator RepA	NA	NA	NA	NA
WP_001067837.1\|54353_55058_+\|transposase	IS6-like element IS26 family transposase	A0A077SL39	Escherichia_phage	5.8e-138	99.1
WP_077459403.1\|55087_55315_+	DsbA family protein	NA	NA	NA	NA
WP_000949451.1\|55304_55811_+	protein disulfide oxidoreductase	NA	NA	NA	NA
WP_012372823.1\|55993_56809_+	Na(+)-translocating NADH-quinone reductase subunit C	NA	NA	NA	NA
WP_001332815.1\|57155_59042_+	FTR1 family iron permease	NA	NA	NA	NA
WP_000178050.1\|59082_59610_+	iron transporter	NA	NA	NA	NA
WP_000119836.1\|59713_61093_+	DUF2318 domain-containing protein	NA	NA	NA	NA
WP_000964653.1\|61095_62379_+	ABC transporter permease	NA	NA	NA	NA
WP_000729218.1\|62368_63499_+	ABC transporter permease	NA	NA	NA	NA
WP_000117262.1\|63503_64199_+	ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	7.5e-29	38.9
WP_001267176.1\|64185_64671_+	TlpA family protein disulfide reductase	NA	NA	NA	NA
WP_000874189.1\|64695_65181_+	hypothetical protein	NA	NA	NA	NA
WP_001189106.1\|66085_66574_-\|transposase	transposase	A0A077SK28	Escherichia_phage	6.7e-24	93.2
WP_000371882.1\|68087_68348_+	hypothetical protein	NA	NA	NA	NA
WP_000194542.1\|68344_68854_+	hypothetical protein	NA	NA	NA	NA
WP_000142452.1\|68873_69221_-	hypothetical protein	NA	NA	NA	NA
WP_001080732.1\|69349_69685_+	colicin transporter	NA	NA	NA	NA
WP_001224623.1\|72154_73030_+	ChaN family lipoprotein	NA	NA	NA	NA
WP_000981091.1\|73037_73814_+	energy transducer TonB	NA	NA	NA	NA
WP_001100763.1\|73982_76244_+	TonB-dependent receptor	NA	NA	NA	NA
WP_001020413.1\|76312_77488_+	enterotoxin production-related protein TieB	NA	NA	NA	NA
WP_000065240.1\|78809_79565_-	ATP-binding protein	U5N3V8	Enterobacteria_phage	3.2e-33	33.9
WP_000143800.1\|79561_81061_-\|transposase	IS21-like element ISEc10 family transposase	NA	NA	NA	NA

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. NC_013654

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CRISPR-Cas detection and classification

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Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection

2. NC_013655

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection