CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Prophage number
NC_012003	Macrococcus caseolyticus JCSC5402 plasmid pMCCL8, complete sequence	0 crisprs	NA	0
NC_011995	Macrococcus caseolyticus JCSC5402 plasmid pMCCL1, complete sequence	0 crisprs	NA	0
NC_011998	Macrococcus caseolyticus JCSC5402 plasmid pMCCL4, complete sequence	0 crisprs	NA	0
NC_011996	Macrococcus caseolyticus JCSC5402 plasmid pMCCL2, complete sequence	0 crisprs	NA	1
NC_012000	Macrococcus caseolyticus JCSC5402 plasmid pMCCL5, complete sequence	0 crisprs	NA	0
NC_012002	Macrococcus caseolyticus JCSC5402 plasmid pMCCL7, complete sequence	0 crisprs	NA	0
NC_012001	Macrococcus caseolyticus JCSC5402 plasmid pMCCL6, complete sequence	0 crisprs	NA	0
NC_011997	Macrococcus caseolyticus JCSC5402 plasmid pMCCL3, complete sequence	0 crisprs	NA	0
NC_011999	Macrococcus caseolyticus JCSC5402, complete genome	3 crisprs	cas3,DEDDh,DinG,csa3	9

Results visualization

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CRISPR-Cas detection and classification

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

17669 : 64009

Streptococcus_phage(23.81%)

protease,transposase

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_012655858.1\|17669_18110_+\|protease	CPBP family intramembrane metalloprotease	NA	NA	NA	NA
WP_158298086.1\|18298_19555_+	toprim domain-containing protein	NA	NA	NA	NA
WP_012655860.1\|19551_20037_+	restriction endonuclease	NA	NA	NA	NA
WP_012655861.1\|20070_20394_+	hypothetical protein	NA	NA	NA	NA
WP_143935715.1\|20476_20695_+	hypothetical protein	NA	NA	NA	NA
WP_148184321.1\|21001_21646_+	class A sortase	NA	NA	NA	NA
WP_148184323.1\|21891_23021_-\|transposase	IS3 family transposase	A0A2I7SC85	Paenibacillus_phage	2.0e-79	55.0
WP_041636585.1\|23326_23704_-	BlaI/MecI/CopY family transcriptional regulator	NA	NA	NA	NA
WP_012655866.1\|23720_25424_-	hypothetical protein	NA	NA	NA	NA
WP_012655867.1\|25507_27532_+	PBP2a family beta-lactam-resistant peptidoglycan transpeptidase MecB	NA	NA	NA	NA
WP_041636568.1\|27538_28399_+	class A beta-lactamase	A0A1B0VBP7	Salmonella_phage	1.4e-24	31.2
WP_012655869.1\|28721_29954_+	DNA adenine methylase	A0A1P8BMM5	Lactococcus_phage	7.5e-32	29.6
WP_148184329.1\|30042_30894_+	Dam family site-specific DNA-(adenine-N6)-methyltransferase	A0A2K9VFX1	Escherichia_phage	5.9e-36	35.3
WP_148184331.1\|30958_32716_+	AlwI family type II restriction endonuclease	NA	NA	NA	NA
WP_041636569.1\|33057_33249_-	hypothetical protein	NA	NA	NA	NA
WP_012655872.1\|33251_33653_-	hypothetical protein	NA	NA	NA	NA
WP_012655873.1\|33812_34469_+	TIR domain-containing protein	NA	NA	NA	NA
WP_012655874.1\|34443_35154_+	hypothetical protein	NA	NA	NA	NA
WP_012655875.1\|35488_35788_+	type II toxin-antitoxin system RelE/ParE family toxin	NA	NA	NA	NA
WP_050742488.1\|35870_36128_+	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_012655876.1\|36346_36928_-	recombinase family protein	A0A0A7NPV4	Enterobacteria_phage	1.6e-40	49.4
WP_012655877.1\|37166_37616_-	hypothetical protein	NA	NA	NA	NA
WP_041636570.1\|37627_37999_-	hypothetical protein	NA	NA	NA	NA
WP_148184327.1\|38034_38331_-	hypothetical protein	NA	NA	NA	NA
WP_041636571.1\|38757_39717_-\|transposase	IS30 family transposase	W5R8L2	Staphylococcus_phage	5.1e-36	34.7
WP_012655880.1\|39932_41168_+	hypothetical protein	NA	NA	NA	NA
WP_012655881.1\|41205_42165_-\|transposase	IS30 family transposase	W5R8L2	Staphylococcus_phage	7.9e-37	35.0
WP_012655882.1\|42411_42705_+	hypothetical protein	NA	NA	NA	NA
WP_050742489.1\|42691_43138_+	YolD-like family protein	A0A1Q1PW34	Staphylococcus_phage	4.0e-15	40.9
WP_001015311.1\|43175_43856_+\|transposase	IS6-like element IS1216 family transposase	A0A1X9I6C6	Streptococcus_phage	1.5e-127	99.6
WP_012655884.1\|44168_45644_+	bifunctional aminoglycoside N-acetyltransferase AAC(6')-Ie/aminoglycoside O-phosphotransferase APH(2'')-Ia	A0A1X9I6C2	Streptococcus_phage	3.3e-284	99.8
WP_001814874.1\|46016_46100_+	23S rRNA methyltransferase attenuation leader peptide	NA	NA	NA	NA
WP_002292226.1\|46224_46962_+	23S rRNA (adenine(2058)-N(6))-methyltransferase Erm(B)	E4ZFQ0	Streptococcus_phage	1.4e-134	99.6
WP_000576156.1\|47316_47871_+	recombinase family protein	A0A0F7LA37	Escherichia_phage	2.3e-36	52.1
WP_001240982.1\|47874_50793_+\|transposase	Tn3 family transposase	A0A1B0V7H9	Salmonella_phage	1.1e-169	36.1
WP_012655885.1\|51099_54063_+\|transposase	Tn3 family transposase	A0A1B0V7H9	Salmonella_phage	6.8e-212	39.9
WP_050742490.1\|54172_54406_+	hypothetical protein	NA	NA	NA	NA
WP_012655886.1\|54617_54935_-	hypothetical protein	NA	NA	NA	NA
WP_001015311.1\|55373_56054_-\|transposase	IS6-like element IS1216 family transposase	A0A1X9I6C6	Streptococcus_phage	1.5e-127	99.6
WP_025906309.1\|56137_56410_+	hypothetical protein	NA	NA	NA	NA
WP_012655887.1\|56431_56737_+	hypothetical protein	NA	NA	NA	NA
WP_012655888.1\|56764_57376_-	recombinase family protein	A0A219YA40	Aeromonas_phage	1.8e-18	36.6
WP_012655889.1\|57702_58278_+	recombinase family protein	M9Q1K0	Clostridium_phage	1.2e-16	30.8
WP_025906304.1\|58361_58853_+	dihydrofolate reductase	A0A076GDN3	Bacillus_phage	2.9e-27	40.9
WP_012655891.1\|58849_59557_+	FAD-dependent thymidylate synthase	M1IEJ2	Bacillus_phage	8.0e-79	60.6
WP_012655892.1\|60100_60553_+	JAB domain-containing protein	A0A1B2LRS6	Wolbachia_phage	4.9e-13	36.1
WP_041636572.1\|60625_60982_+	hypothetical protein	NA	NA	NA	NA
WP_012655894.1\|61565_61955_+	hypothetical protein	NA	NA	NA	NA
WP_041636573.1\|62574_62823_+	hypothetical protein	NA	NA	NA	NA
WP_041636574.1\|62886_63117_+	hypothetical protein	NA	NA	NA	NA
WP_012655895.1\|63202_64009_+	ParA family protein	A0A1X9I765	Streptococcus_phage	8.7e-37	35.8

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

2. NC_011999

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CRISPR-Cas detection and classification

Crispr_ID: NC_011999_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_011999_1

1516380-1516470

Orphan

Consensus_repeat	Method
GGAGACTTTTTGCGGATAAAGGGAGAC	CRISPRCasFinder

1 spacers

csa3

The CRISPR arrays of NC_011999_1

>merge|NC_011999|1|1516380-1516470|CRISPRCasFinder
GGAGACTTTTTGCGGATAAAGGGAGACTTTTTGCGGATTTAAAGGAGACTTTTTGCGGATAAAGGGAGACTTTTTGCGGATAAAGGGAGAC

>NC_011999|1|1|1516380-1516470|CRISPRCasFinder
GGAGACTTTTTGCGGATAAAGGGAGAC	TTTTTGCGGATTTAAAGGAGACTTTTTGCGGATAAAG
GGAGACTTTTTGCGGATAAAGGGAGAC

Protein	Signature genes	Signature genes Name	Protein_function
NC_011999.1\|WP_012657307.1\|1518834_1519431_-\|1-acyl-sn-glycerol-3-phosphate-acyltransferase	unknown	unknown	gnl\|CDD\|153251
NC_011999.1\|WP_041636081.1\|1518287_1518494_+\|hypothetical-protein	unknown	unknown	unknown
NC_011999.1\|WP_012657313.1\|1526348_1528016_-\|formate--tetrahydrofolate-ligase	unknown	unknown	gnl\|CDD\|237403
NC_011999.1\|WP_012657297.1\|1507703_1509014_+\|cation:dicarboxylase-symporter-family-transporter	unknown	unknown	gnl\|CDD\|183075
NC_011999.1\|WP_041636080.1\|1515547_1515922_+\|single-stranded-DNA-binding-protein	unknown	unknown	gnl\|CDD\|377790
NC_011999.1\|WP_012657303.1\|1513980_1514316_-\|helix-turn-helix-transcriptional-regulator	csa3	COG0640_csa3_CAS-I-A	gnl\|CDD\|197713
NC_011999.1\|WP_012657302.1\|1513244_1513811_-\|tyrosine-type-recombinase/integrase	unknown	unknown	gnl\|CDD\|271192
NC_011999.1\|WP_012657311.1\|1522326_1523580_-\|tyrosine--tRNA-ligase	unknown	unknown	gnl\|CDD\|235645
NC_011999.1\|WP_012657310.1\|1521673_1522258_-\|LemA-family-protein	unknown	unknown	gnl\|CDD\|377192
NC_011999.1\|WP_041636077.1\|1509036_1509996_-\|IS30-family-transposase	unknown	unknown	gnl\|CDD\|225382
NC_011999.1\|WP_041636084.1\|1519557_1520751_+\|trypsin-like-peptidase-domain-containing-protein	unknown	unknown	gnl\|CDD\|273938
NC_011999.1\|WP_012657300.1\|1510835_1512356_+\|ABC-F-family-ATP-binding-cassette-domain-containing-protein	unknown	unknown	gnl\|CDD\|223562
NC_011999.1\|WP_012657304.1\|1514335_1514953_-\|CadD-family-cadmium-resistance-transporter	unknown	unknown	gnl\|CDD\|281580
NC_011999.1\|WP_120786731.1\|1516058_1516154_-\|type-I-toxin-antitoxin-system-Fst-family-toxin	unknown	unknown	unknown
NC_011999.1\|WP_012657306.1\|1516541_1518044_-\|histidine-ammonia-lyase	unknown	unknown	gnl\|CDD\|236484
NC_011999.1\|WP_158298081.1\|1510108_1510813_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|340863
NC_011999.1\|WP_012657312.1\|1523914_1526263_+\|penicillin-binding-protein	unknown	unknown	gnl\|CDD\|223815
NC_011999.1\|WP_012657301.1\|1512907_1513231_+\|hypothetical-protein	unknown	unknown	unknown
NC_011999.1\|WP_012657309.1\|1520822_1521674_-\|TPM-domain-containing-protein	unknown	unknown	gnl\|CDD\|224429
NC_011999.1\|WP_041636082.1\|1518574_1518787_+\|hypothetical-protein	unknown	unknown	unknown

Protein	Function_ID	Function_description	E-value
NC_011999.1\|WP_041636084.1\|1519557_1520751_+\|trypsin-like-peptidase-domain-containing-protein	gnl\|CDD\|273938	TIGR02037, Probable_periplasmic_serine_protease_do/HhoA-like, periplasmic serine protease, Do/DeqQ family. This family consists of a set proteins various designated DegP, heat shock protein HtrA, and protease DO. The ortholog in Pseudomonas aeruginosa is designated MucD and is found in an operon that controls mucoid phenotype. This family also includes the DegQ (HhoA) paralog in E. coli which can rescue a DegP mutant, but not the smaller DegS paralog, which cannot. Members of this family are located in the periplasm and have separable functions as both protease and chaperone. Members have a trypsin domain and two copies of a PDZ domain. This protein protects bacteria from thermal and other stresses and may be important for the survival of bacterial pathogens.// The chaperone function is dominant at low temperatures, whereas the proteolytic activity is turned on at elevated temperatures. [Protein fate, Protein folding and stabilization, Protein fate, Degradation of proteins, peptides, and glycopeptides].	2.69927e-88
NC_011999.1\|WP_012657313.1\|1526348_1528016_-\|formate--tetrahydrofolate-ligase	gnl\|CDD\|237403	PRK13505, PRK13505, formate--tetrahydrofolate ligase; Provisional.	0
NC_011999.1\|WP_012657297.1\|1507703_1509014_+\|cation:dicarboxylase-symporter-family-transporter	gnl\|CDD\|183075	PRK11283, gltP, glutamate/aspartate:proton symporter; Provisional.	1.62822e-175
NC_011999.1\|WP_041636080.1\|1515547_1515922_+\|single-stranded-DNA-binding-protein	gnl\|CDD\|377790	pfam07205, DUF1413, Domain of unknown function (DUF1413). This family consists of several hypothetical bacterial proteins which seem to be specific to firmicute species. Members of this family are typically around 100 residues in length. The function of this family is unknown.	1.96738e-17
NC_011999.1\|WP_012657303.1\|1513980_1514316_-\|helix-turn-helix-transcriptional-regulator	gnl\|CDD\|197713	smart00418, HTH_ARSR, helix_turn_helix, Arsenical Resistance Operon Repressor.	1.06816e-14
NC_011999.1\|WP_012657302.1\|1513244_1513811_-\|tyrosine-type-recombinase/integrase	gnl\|CDD\|271192	cd01192, INT_C_like_3, Uncharacterized site-specific tyrosine recombinase, C-terminal catalytic domain. Tyrosine recombinase (integrase) belongs to a DNA breaking-rejoining enzyme superfamily. The catalytic domain contains six conserved active site residues. The recombination reaction involves cleavage of a single strand of a DNA duplex by nucleophilic attack of a conserved tyrosine to give a 3' phosphotyrosyl protein-DNA adduct. In the second rejoining step, a terminal 5' hydroxyl attacks the covalent adduct to release the enzyme and generate duplex DNA. Many DNA breaking-rejoining enzymes also have N-terminal domains, which show little sequence or structure similarity.	1.79517e-52
NC_011999.1\|WP_012657311.1\|1522326_1523580_-\|tyrosine--tRNA-ligase	gnl\|CDD\|235645	PRK05912, PRK05912, tyrosyl-tRNA synthetase; Validated.	0
NC_011999.1\|WP_012657310.1\|1521673_1522258_-\|LemA-family-protein	gnl\|CDD\|377192	pfam04011, LemA, LemA family. The members of this family are related to the LemA protein. LemA contains an amino terminal predicted transmembrane helix. It has been predicted that the small amino terminus is extracellular. The exact molecular function of this protein is uncertain.	2.51459e-83
NC_011999.1\|WP_041636077.1\|1509036_1509996_-\|IS30-family-transposase	gnl\|CDD\|225382	COG2826, Tra8, Transposase and inactivated derivatives, IS30 family [DNA replication, recombination, and repair].	4.56826e-58
NC_011999.1\|WP_012657304.1\|1514335_1514953_-\|CadD-family-cadmium-resistance-transporter	gnl\|CDD\|281580	pfam03596, Cad, Cadmium resistance transporter.	2.62399e-83
NC_011999.1\|WP_012657306.1\|1516541_1518044_-\|histidine-ammonia-lyase	gnl\|CDD\|236484	PRK09367, PRK09367, histidine ammonia-lyase; Provisional.	0
NC_011999.1\|WP_158298081.1\|1510108_1510813_+\|hypothetical-protein	gnl\|CDD\|340863	cd06173, MFS_MefA_like, Macrolide efflux protein A and similar proteins of the Major Facilitator Superfamily of transporters. This family is composed of Streptococcus pyogenes macrolide efflux protein A (MefA) and similar transporters, many of which remain uncharacterized. Some members may be multidrug resistance (MDR) transporters, which are drug/H+ antiporters (DHAs) that mediate the efflux of a variety of drugs and toxic compounds, conferring resistance to these compounds. MefA confers resistance to 14-membered macrolides including erythromycin and to 15-membered macrolides. It functions as an efflux pump to regulate intracellular macrolide levels. The MefA-like family belongs to the Major Facilitator Superfamily (MFS) of membrane transport proteins, which are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	3.51462e-18
NC_011999.1\|WP_012657312.1\|1523914_1526263_+\|penicillin-binding-protein	gnl\|CDD\|223815	COG0744, MrcB, Membrane carboxypeptidase (penicillin-binding protein) [Cell envelope biogenesis, outer membrane].	1.99658e-155
NC_011999.1\|WP_012657300.1\|1510835_1512356_+\|ABC-F-family-ATP-binding-cassette-domain-containing-protein	gnl\|CDD\|223562	COG0488, Uup, ATPase components of ABC transporters with duplicated ATPase domains [General function prediction only].	6.28736e-83
NC_011999.1\|WP_012657309.1\|1520822_1521674_-\|TPM-domain-containing-protein	gnl\|CDD\|224429	COG1512, COG1512, Beta-propeller domains of methanol dehydrogenase type [General function prediction only].	1.56751e-29
NC_011999.1\|WP_012657307.1\|1518834_1519431_-\|1-acyl-sn-glycerol-3-phosphate-acyltransferase	gnl\|CDD\|153251	cd07989, LPLAT_AGPAT-like, Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: AGPAT-like. Lysophospholipid acyltransferase (LPLAT) superfamily member: acyltransferases of de novo and remodeling pathways of glycerophospholipid biosynthesis which catalyze the incorporation of an acyl group from either acylCoAs or acyl-acyl carrier proteins (acylACPs) into acceptors such as glycerol 3-phosphate, dihydroxyacetone phosphate or lyso-phosphatidic acid. Included in this subgroup are such LPLATs as 1-acyl-sn-glycerol-3-phosphate acyltransferase (AGPAT, PlsC), Tafazzin (product of Barth syndrome gene), and similar proteins.	2.57392e-36

>NC_011999.1|WP_120786731.1|1516058_1516154_-|type-I-toxin-antitoxin-system-Fst-family-toxin
MLTIFVQVLCSIVSGCIVALFSHWLSLNKKK
>NC_011999.1|WP_041636080.1|1515547_1515922_+|single-stranded-DNA-binding-protein
MKNNQISLRFNEEEFKALQKKALADGRTASAYAKEVILNNLGIVSTEKDLTLNEVHEKAQKFDSKKAFAIRDLFTDDEWGSFSKASRLSVGRLFFNSTKENGQYHDYYRFVDKKSSNLAYYVKL
>NC_011999.1|WP_012657304.1|1514335_1514953_-|CadD-family-cadmium-resistance-transporter
MFQTIITATVLYTATAVDLLVILLIFFARASTKKEYRNIYIGQYLGSIILILLSLFLAFVLNYVPEKWMLGLLGIIPIYFGVKVALYDDCAGEKRAKKELDKKGLSKLIGTVALVTIASCGADNIGLFVPYFVSLNMSNLIVTLITFLVLIFVLVFTAQKIANIPGIGGTIEKYSRWIMAVIYIGLGMFIIIENKTIQTILEFLF
>NC_011999.1|WP_012657303.1|1513980_1514316_-|helix-turn-helix-transcriptional-regulator
MNKSITCDIVCVHEDKVDKALDFLKIEKSQRLLNIFQKICDEKKLKIVLSLLSEKELCVCDIAIILDMSVASTSHHLRLLYKNDVLDFYKKGKMAYYFIKDEEIKLFFSNN
>NC_011999.1|WP_012657302.1|1513244_1513811_-|tyrosine-type-recombinase/integrase
MNSVEPIRDVQKIQEMKEALAYYGSERDVFLFNLGINCGLRVSDMLGLKKKDIKDYTIKLREQKTRKQKQIPLYHLKEDIDRYIQFLEDEDYLFKSNKLDFEGKSKPISRVQAYRILNHSAKSIGLSEIGTHSMRKTFGYHYYKKTKDVALLMDLFSHSSQAVTLRYIGINQDMMNDSISKAMINIYF
>NC_011999.1|WP_012657301.1|1512907_1513231_+|hypothetical-protein
MGNLIEHKYSSSHIFDNSLIVNNENKESNLEFFIQYYLLSQKKALKLLEEDINNKSKEDSSKLLIKDIKMSKENWDDFQSIINDFLSTLDGEENQLNIQISLSAIVD
>NC_011999.1|WP_012657300.1|1510835_1512356_+|ABC-F-family-ATP-binding-cassette-domain-containing-protein
MRNGINISNHDVTIQDNILFKIKKIIITKKDRIGIVAMNGTGKTTFLKNIKAHNTFDTINSNWDIKMLDQLPTHENLSGGEIVKKELEKVFNSTADCVLLDEPTSNLDSKNIKWLINKISETDKAVVIVSHDRNFLNKTVNKILYIEDEYLQVYIGNYDEYEEEMNKKYEKDLNLYKKQQYKKKKIEQEIIKKKNISKNLQKIKKGVSSSDWKDSRVTGGYESKEKSIAKQAKSLEKRISREFNFKKTYIQKDIKIQATGNLSLKKGTTLYNLNKVQIRNKDNSILNLNNLKIEFGDHIGIIGDNGSGKTTILEYLYSQNIRDCEEIYVYDNVSVGYFDQLLKQSNNNYTVLDIVSENSEQDKQVIFDTLGSLSINKDDMFKRYENLSGGQKVRVNIAKVLLGNHHLLLLDEPNNYLDIYAIKALESYLKNYPSTFILVSHDETLVKNTCEKIFILENNKLIDARKNSRYSNNNTDIQKSFLKDLAIINGESKEMEDLNQYIKKKL
>NC_011999.1|WP_158298081.1|1510108_1510813_+|hypothetical-protein
MEIIAVLFFLNINFRKNAIIEQDNEVENNKNSYSILNSVKYMLKKSKLSSLILGMFLMNFLLSALTIGLPVIMNEYFEKNTTALGIIQSSIPLGMIISGIVFVYIKINPNNLKITIISWLFCSILLIFIGLDLLLFRNNIFIFSVFLIIVNLFLGISLTAGKIPILTYSQKTINPHYQGRVFSILDVLIQVSIPLGILIYGFLFEFFNAINIFITTGIFVLILTTLTYRKISSI
>NC_011999.1|WP_041636077.1|1509036_1509996_-|IS30-family-transposase
MAYKHLNTDELTFIESYYHQDLSVKEIAKRLKRSRQTIYNVVNALKTGITALEYYQEYKQRKSNCGRHRIVLPENQSAYIREKVADGWTPDTIIGRGEHPIDCSVKTLYRMFKENVFSVQSLPMKGKRKPNGHCEKRGRQAFKRHISERIEEFPFFFQEFGHLEGDTIIGRNHGSAVITLVERISKMIITIRPQGRKADDIEDALHSMFSALPPHIFKSITFDCGKEFSNWKTICNRHDISIFFADPGTPSQRGLNEHSNGILRRSGLDKELDFNSVTDDHIISVAQNINHRPRKSLGYKTPLEVFMSFIEDEKLSSLF
>NC_011999.1|WP_012657297.1|1507703_1509014_+|cation:dicarboxylase-symporter-family-transporter
MSSVTEIKKPKKKKFISLPMQILIALILGVVVGALLNGQKEYVNYFQPLGDIFLHLIKMIVVPIVFCSLVISIAGTGDMKTVGRYGWKTLLYFEIITTLAIGLGIIFANVFKPGAGINKDLLPKGDVTKYTTNAEAAAESTYGNHMIDTIVNIIPTNIIDSMAQGQLLPVIFFSVFFGLGLAAIGKKGDPVRAFFDGFLDVIFWMTNQIMKYAPIGVFAFMAVTIINLGLGALIPLGKLALVVAGSMVFFIIVVLGAVAAMCKINIFHLLRILKDELLLAFSTSSSETVLPVIMDKMEKFGAPKEIVSFVIPTGYTFNLDGSALYQSIAALTIAQMYGVHLSVTEQLVLLLTLMLTSKGMAAVPGTSIVVLITTLTAMNIHPEGLALIIGIDRILDMMRTVVNVVGNSLSTLVIARWENRLDYEKSRKYYETYVNK
>NC_011999.1|WP_012657306.1|1516541_1518044_-|histidine-ammonia-lyase
MNLVLNGQDLTIESIKVLIAQDQNVEICEEALSRVKQSRKIVDDIIADQETVYGITTGFGLFSDVLIDQDKYEDLQLNLIRSHACGIGEPFNDDVALVMMILRLNTMLKGHSGVSTALVEQLVFFINQRIFPVIPAQGSLGASGDLAPLSHLALALVGEGEVIYKGVRQESSKVLQSLNRAPHTLQAKEGLALINGTQAMTSQGVISYIEAEQLAYDAEWIAALTHQALNGIVDAYDAHVHIVRNSKEQLSVANRMLDWLEGSSLTTRQGELRVQDAYSLRCIPQIHGASFQVLNYVKEKLECEMNAANDNPLIFDKDDETLVISGGNFHGQPVAFALDFLKIGVSELSNVSERRIERLVNPQLNGDLPAFLSPHPGLQSGAMIMQYAAASLVSENKTLAHPASVDSIPSSANQEDHVSMGTIASRHGYQIVENVRNVLAIECVIALQAVELKGVDKLSQKTKEKYEEYREFVPSITEDRQFHKDIKVVSDYLKRSAYKK
>NC_011999.1|WP_041636081.1|1518287_1518494_+|hypothetical-protein
MQILPQLFKGKLTAYQISTATDIDIATIESLFEDEAAVSSLDEATYLTLKQLEDELFNNDHRTGETTA
>NC_011999.1|WP_041636082.1|1518574_1518787_+|hypothetical-protein
MGVILLKASYPDTSQEHTEYKIIQNECEKVRYINQARNEFYKRMHRSDDEQVIKLEFIYPDDIETYYYKA
>NC_011999.1|WP_012657307.1|1518834_1519431_-|1-acyl-sn-glycerol-3-phosphate-acyltransferase
MYQFISRIIFFFVKILNKLKVSDKHHLPEDEAFIVTCNHESRVEIIMLAMSLYPLEIHYMAKQELFKTPLLNRFFRSVNAFPVNRENPGPSTLKIPVKLIKEGKIVGIFPSGQRNNAAPMKKGAATIAVLSKSTIVPAAYTGPLKFRDVIFKRQKCWIKFGAPIDSTTYLSQYNKTEAIEKITQQLEKSTKSIIVTMK
>NC_011999.1|WP_041636084.1|1519557_1520751_+|trypsin-like-peptidase-domain-containing-protein
MEQNNEYYNENSHLKAQHPKQQKAGFLKMVLAGVVGSVLTLGVTELPEYFSHDETETISPVTVDNTTTSKSTSNLSQMLEQVSPAIVGVINIQQAPSSIYDILSGNRSTDTTPAGTGSGVIYQVDGNNTYIVTNNHVVEGAKELKVKLSNGKTIDAELMGTDALTDIAVLKVTGQLNIKPVAFADSSKIRIGEPVYAIGNPLGLELAGTVTEGIVSSKERTMKVETSAGNASVKVIQTDAAINPGNSGGALINTSGQLIGINSMKISANQVEGIGFAIPSNDTKTIIEQLVKNGKVERPYIGLGLVGISDVPADYLKELKITQTKGVVVAQTDSVSRTKFNKGDVITAINGHKVESDSDVRNYIYTHHKAGDNVKFTVYRGDKKTEVTMTLRSTNNK
>NC_011999.1|WP_012657309.1|1520822_1521674_-|TPM-domain-containing-protein
MRRFTIFFASLLVFLTALPVSAAEPLPKLEQPRFVQDHIGIFKQQEKDALNQKGETLHSGTTAEILLMTMPSIGQEVKEDYALRAGREYGVGDKDKDNGIVILLNLDNNNENNNRGIEVMVGPGLQGVLNDAKVGRMIDTYAMPDIQKAMQADPDAKSETSRHYYAQAMIKLYNAIFDEISKSYGFDGEKYTRDTPIATQDDSVGNVSVFEIIIALFFLYLILSMFFGGGGRGGGGRGGRSKGPVIFFPTGGGFSSGGFSGGGFSGGGFGGGGFDGGGAGRSF
>NC_011999.1|WP_012657310.1|1521673_1522258_-|LemA-family-protein
MKKLLVPVIGLIVLLLVIGSMLIGPYNKLVDLDTEVEKSQAKIDTQLQRRLDLIPNLVETVKGYAKHEEKVFKDVSDARAKLAGANTMEEKAEANEQVSSALSRLIAIQENYPELKADTQFTGLRDELAGTENRIAVARNDYNDVVTEYNKVVKRFPGSIVAGLFGFEKKEFFKADSAAKDAPNVDFNSDKDSE
>NC_011999.1|WP_012657311.1|1522326_1523580_-|tyrosine--tRNA-ligase
MTSALLEDLRWRGLIYQETHPEEMEALLNKESVSVYCGTDPTADSLHIGHLLPFMTLKRFQAHGHRPVVLIGGATGMIGDPSGRTDERTLQTLAQVQHNVDGISKQMEQLFDFGTENGAIRVDNKDWLGKIDLLTFLRDYGKHVGVNYLLNKDSIASRLETGISFTEFTYTILQAIDFGHLNKTLNVKLQIGGSDQWGNITSGMELMRRMYGEVEAYGMTVPLVVKSDGKKFGKSEGGAVWLDRTKTTPYEFYQFWINTPDSDVIKFLKYFTFLSKEEIDALETSVENEPHLRLAQKRLAEEVTKYVHDESALEEAVNITDALFKGDLKALTADQLRTSFKDVPQAKVTTTNLVELLIEAGISPSKRQAREDITNGAISINGEKVQDVAYEIVATDKIEDEFTIIRRGKKKYFMIIH
>NC_011999.1|WP_012657312.1|1523914_1526263_+|penicillin-binding-protein
MANKTSYKDKFKRQLIGYKEGFKNIKFTPYVIFNGLYETVSKTLLFLITAGILFATLMFGIGSGYFLALVKDEPVKSNSELKKSLYEMTQSTTVYFGSGETLGNLNADTQRQVVKLKDMSPHVKDALIATEDESFYRHRGIVPKAFIRATAQEFLNTGVTSGGSTLTQQLIKNQLLTNETSFQRKAKEMMLSFKVEKALTKDEIIEAYLNVVSFGRNTNGQNIAGIEAAAQGIFGVKANELNIAQAAYIAGLPQNPYTYTPFLQDGSVKSKDDLAYGLTRQQYVLSRMYQENKISKAEFDKAKSFNIVKSFTKDVETPNEKYPFLTQEVEDEAVDILKYHFASKDNVSKTELDETPVLQEKYTNIAERAVRNDGYIVETTINKPIFDAMNAVKDNPNYYSYDRQVEVGGKTKSLSQEVGVLLKENKTGKIIAFVGGRDHDKSQNNHAMKTKRSPGSTIKPLLTYAPAMEYGITAPETMLLDKKFNYNGYEPENYARMEYGNVTTRYALENSLNLSTLRLYSSIQDKKPWELLNKMDFNIPESEQENLSLALGATDITLKNDVDGFSTLANGGNYQESYMIERIKAKDGKVIYQHEAKPERIYSASTAYMTTDMLRGVLDTGSAYSLKGTFLYNQDWAGKTGTTQDAKDSLFVAYNPKVTMGIWMGYDVPTTFDEENHYQLKLWRDIVNQISSIDQSQMGVGERFNQPKSVTKQNICQFTNNTSGCVSGESTKESLVSDKTDLTQKTLDTPDVLNRLGIKLDPATKSKIFTKSKQNTQKKKRN
>NC_011999.1|WP_012657313.1|1526348_1528016_-|formate--tetrahydrofolate-ligase
MTKYLSDLEIANQATIKPIAEIAEAAGIPDNAVEPYGHYKAKIDTSKVTTDKQGKVVLVTAMSPTPAGEGKSTVTVGISDAFKALGKNVMVALREPSLGPVFGMKGGATGGGHAQVLPMEEINLHFNGDLHAITTANNALAAFIDNHIYQGNKLNIDPRRVEWKRVIDMNDRALRQVVVGLGGPFKGVPREDGFDITVASEIMAVFCLSNNIEDLKENLGKMTIGYTYDRKPVTVKELGVEGALALILKDALKPNLVQTIEGTPALIHGGPFANIAHGCNSIIATKTARKLADIVVTESGFGSDLGAEKFMDIKARKADIQPDAIVVVATIRALKMHGGVAKTELSAENVEALKSGIQNLEKHIENLNQFGVESVIALNNFVTDTDAEREFVIKWAKERGVKLALTEVWEHGGEGGKDLANLVLEVLEQPQSFKPLYDLSLPVEEKIRTIVQKIYGADDVVFTDKAKKQLKTITDNGWNEYPVCMAKTQYSFSDDPKKLGRPSGFEITIRELIPKTGAGFIVALTGDIMTMPGLPKEPAALRMDVDKEGNAVGLF

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Crispr_ID: NC_011999_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_011999_2

1575516-1575605

Orphan

Consensus_repeat	Method
TTGGCTCATGTTTATTTTTTATGAGCCA	CRISPRCasFinder

1 spacers

The CRISPR arrays of NC_011999_2

>merge|NC_011999|2|1575516-1575605|CRISPRCasFinder
TTGGCTCATGTTTATTTTTTATGAGCCAACTTTGCCATTCTCCACACGCAACGAGCAACTTCTTGGCTCATGTTTATTTTTTATGAGCCA

>NC_011999|2|2|1575516-1575605|CRISPRCasFinder
TTGGCTCATGTTTATTTTTTATGAGCCA	ACTTTGCCATTCTCCACACGCAACGAGCAACTTC
TTGGCTCATGTTTATTTTTTATGAGCCA

Protein	Signature genes	Signature genes Name	Protein_function
NC_011999.1\|WP_041636092.1\|1569954_1570512_-\|energy-coupled-thiamine-transporter-ThiT	unknown	unknown	gnl\|CDD\|370542
NC_011999.1\|WP_012657358.1\|1572270_1573461_-\|bifunctional-3,4-dihydroxy-2-butanone-4-phosphate-synthase/GTP-cyclohydrolase-II	unknown	unknown	gnl\|CDD\|181774
NC_011999.1\|WP_012657354.1\|1568565_1569660_-\|AAA-family-ATPase	unknown	unknown	gnl\|CDD\|273670
NC_011999.1\|WP_041636090.1\|1566377_1566896_+\|helix-turn-helix-domain-containing-protein	unknown	unknown	gnl\|CDD\|225511
NC_011999.1\|WP_012657356.1\|1570780_1571773_+\|proline-dehydrogenase-family-protein	unknown	unknown	gnl\|CDD\|223580
NC_011999.1\|WP_012657352.1\|1567039_1567771_+\|IS3-family-transposase	unknown	unknown	gnl\|CDD\|222853
NC_011999.1\|WP_012657359.1\|1573460_1574084_-\|riboflavin-synthase	unknown	unknown	gnl\|CDD\|236455
NC_011999.1\|WP_012657367.1\|1583188_1583833_+\|ABC-transporter-permease	unknown	unknown	gnl\|CDD\|224095
NC_011999.1\|WP_012657357.1\|1571809_1572274_-\|6,7-dimethyl-8-ribityllumazine-synthase	unknown	unknown	gnl\|CDD\|234606
NC_011999.1\|WP_012657364.1\|1579561_1580497_-\|formimidoylglutamase	unknown	unknown	gnl\|CDD\|184317
NC_011999.1\|WP_012657370.1\|1585488_1586349_+\|hypothetical-protein	unknown	unknown	unknown
NC_011999.1\|WP_012657365.1\|1580489_1581941_-\|FAD/NAD(P)-binding-protein	unknown	unknown	gnl\|CDD\|226906
NC_011999.1\|WP_012657366.1\|1582056_1583187_+\|betaine/proline/choline-family-ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|224050
NC_011999.1\|WP_012657368.1\|1583833_1584733_+\|osmoprotectant-ABC-transporter-substrate-binding-protein	unknown	unknown	gnl\|CDD\|270326
NC_011999.1\|WP_012657363.1\|1578714_1579602_+\|LysR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|223656
NC_011999.1\|WP_012657360.1\|1574088_1575114_-\|bifunctional-diaminohydroxyphosphoribosylaminopyrimidine-deaminase/5-amino-6-(5-phosphoribosylamino)uracil-reductase-RibD	unknown	unknown	gnl\|CDD\|273015
NC_011999.1\|WP_041636463.1\|1575682_1576915_-\|imidazolonepropionase	unknown	unknown	gnl\|CDD\|236478
NC_011999.1\|WP_012657353.1\|1567817_1568555_-\|nicotinamide-mononucleotide-transporter	unknown	unknown	gnl\|CDD\|377432
NC_011999.1\|WP_012657369.1\|1584732_1585425_+\|ABC-transporter-permease	unknown	unknown	gnl\|CDD\|224095
NC_011999.1\|WP_041636093.1\|1576933_1578583_-\|urocanate-hydratase	unknown	unknown	gnl\|CDD\|235448

Protein	Function_ID	Function_description	E-value
NC_011999.1\|WP_041636092.1\|1569954_1570512_-\|energy-coupled-thiamine-transporter-ThiT	gnl\|CDD\|370542	pfam09515, Thia_YuaJ, Thiamine transporter protein (Thia_YuaJ). Members of this protein family have been assigned as thiamine transporters by a phylogenetic analysis of families of genes regulated by the THI element, a broadly conserved RNA secondary structure element through which thiamine pyrophosphate (TPP) levels can regulate transcription of many genes related to thiamine transport, salvage, and de novo biosynthesis. Species with this protein always lack the ThiBPQ ABC transporter. In some species (e.g. Streptococcus mutans and Streptococcus pyogenes), yuaJ is the only THI-regulated gene. Evidence from Bacillus cereus indicates thiamine uptake is coupled to proton translocation.	5.82492e-51
NC_011999.1\|WP_012657358.1\|1572270_1573461_-\|bifunctional-3,4-dihydroxy-2-butanone-4-phosphate-synthase/GTP-cyclohydrolase-II	gnl\|CDD\|181774	PRK09311, PRK09311, bifunctional 3,4-dihydroxy-2-butanone-4-phosphate synthase/GTP cyclohydrolase II.	0
NC_011999.1\|WP_012657354.1\|1568565_1569660_-\|AAA-family-ATPase	gnl\|CDD\|273670	TIGR01526, nadR_NMN_Atrans, nicotinamide-nucleotide adenylyltransferase, NadR type. The NadR protein of E. coli and closely related bacteria is both enzyme and regulatory protein. The first 60 or so amino acids, N-terminal to the region covered by this model, is a DNA-binding helix-turn-helix domain (pfam01381) responsible for repressing the nadAB genes of NAD de novo biosynthesis. The NadR homologs in Mycobacterium tuberculosis, Haemophilus influenzae, and others appear to lack the repressor domain. NadR has recently been shown to act as an enzyme of the salvage pathway of NAD biosynthesis, nicotinamide-nucleotide adenylyltransferase; members of this family are presumed to share this activity. E. coli NadR has also been found to regulate the import of its substrate, nicotinamide ribonucleotide, but it is not known if the other members of this model share that activity.	1.68871e-72
NC_011999.1\|WP_041636090.1\|1566377_1566896_+\|helix-turn-helix-domain-containing-protein	gnl\|CDD\|225511	COG2963, COG2963, Transposase and inactivated derivatives [DNA replication, recombination, and repair].	4.45525e-09
NC_011999.1\|WP_012657356.1\|1570780_1571773_+\|proline-dehydrogenase-family-protein	gnl\|CDD\|223580	COG0506, PutA, Proline dehydrogenase [Amino acid transport and metabolism].	1.29772e-64
NC_011999.1\|WP_012657352.1\|1567039_1567771_+\|IS3-family-transposase	gnl\|CDD\|222853	PHA02517, PHA02517, putative transposase OrfB; Reviewed.	7.28955e-41
NC_011999.1\|WP_012657359.1\|1573460_1574084_-\|riboflavin-synthase	gnl\|CDD\|236455	PRK09289, PRK09289, riboflavin synthase.	3.98948e-86
NC_011999.1\|WP_012657367.1\|1583188_1583833_+\|ABC-transporter-permease	gnl\|CDD\|224095	COG1174, OpuBB, ABC-type proline/glycine betaine transport systems, permease component [Amino acid transport and metabolism].	7.87312e-79
NC_011999.1\|WP_012657357.1\|1571809_1572274_-\|6,7-dimethyl-8-ribityllumazine-synthase	gnl\|CDD\|234606	PRK00061, ribH, 6,7-dimethyl-8-ribityllumazine synthase; Provisional.	3.09136e-82
NC_011999.1\|WP_012657364.1\|1579561_1580497_-\|formimidoylglutamase	gnl\|CDD\|184317	PRK13774, PRK13774, formimidoylglutamase; Provisional.	0
NC_011999.1\|WP_012657365.1\|1580489_1581941_-\|FAD/NAD(P)-binding-protein	gnl\|CDD\|226906	COG4529, COG4529, Uncharacterized protein conserved in bacteria [Function unknown].	5.50385e-34
NC_011999.1\|WP_012657366.1\|1582056_1583187_+\|betaine/proline/choline-family-ABC-transporter-ATP-binding-protein	gnl\|CDD\|224050	COG1125, OpuBA, ABC-type proline/glycine betaine transport systems, ATPase components [Amino acid transport and metabolism].	2.10069e-147
NC_011999.1\|WP_012657368.1\|1583833_1584733_+\|osmoprotectant-ABC-transporter-substrate-binding-protein	gnl\|CDD\|270326	cd13608, PBP2_OpuCC_like, Substrate-binding protein OpuCC of ABC-type osmoregulatory transporter and related proteins; the type 2 periplasmic-binding protein fold. This subfamily includes the periplasmic substrate-binding protein OpuCC of the ABC transporter OpuC (where Opu is osmoprotectant uptake), which can recognize a broad spectrum of compatible solutes, and its paralog OpuBC that can solely bind choline. To counteract the efflux of water, many microorganisms accumulate the compatible solutes for a sustained adjustment to high osmolarity surroundings. This substrate-binding domain belongs to the type 2 periplasmic binding fold protein superfamily (PBP2). The PBP2 proteins are typically comprised of two globular subdomains connected by a flexible hinge and bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap.	3.08473e-175
NC_011999.1\|WP_012657363.1\|1578714_1579602_+\|LysR-family-transcriptional-regulator	gnl\|CDD\|223656	COG0583, LysR, Transcriptional regulator [Transcription].	1.96829e-43
NC_011999.1\|WP_012657360.1\|1574088_1575114_-\|bifunctional-diaminohydroxyphosphoribosylaminopyrimidine-deaminase/5-amino-6-(5-phosphoribosylamino)uracil-reductase-RibD	gnl\|CDD\|273015	TIGR00326, eubact_ribD, riboflavin biosynthesis protein RibD. This model describes the ribD protein as found in Escherichia coli. The N-terminal domain includes the conserved zinc-binding site region captured in the model dCMP_cyt_deam and shared by proteins such as cytosine deaminase, mammalian apolipoprotein B mRNA editing protein, blasticidin-S deaminase, and Bacillus subtilis competence protein comEB. The C-terminal domain is homologous to the full length of yeast HTP reductase, a protein required for riboflavin biosynthesis. A number of archaeal proteins believed related to riboflavin biosynthesis contain only this C-terminal domain and are not found as full-length matches to this model. [Biosynthesis of cofactors, prosthetic groups, and carriers, Riboflavin, FMN, and FAD].	1.6142e-87
NC_011999.1\|WP_041636463.1\|1575682_1576915_-\|imidazolonepropionase	gnl\|CDD\|236478	PRK09356, PRK09356, imidazolonepropionase; Validated.	0
NC_011999.1\|WP_012657353.1\|1567817_1568555_-\|nicotinamide-mononucleotide-transporter	gnl\|CDD\|377432	pfam04973, NMN_transporter, Nicotinamide mononucleotide transporter. Members of this family are integral membrane proteins that are involved in transport of nicotinamide mononucleotide.	5.3088e-41
NC_011999.1\|WP_012657369.1\|1584732_1585425_+\|ABC-transporter-permease	gnl\|CDD\|224095	COG1174, OpuBB, ABC-type proline/glycine betaine transport systems, permease component [Amino acid transport and metabolism].	1.17517e-79
NC_011999.1\|WP_041636093.1\|1576933_1578583_-\|urocanate-hydratase	gnl\|CDD\|235448	PRK05414, PRK05414, urocanate hydratase; Provisional.	0

>NC_011999.1|WP_012657360.1|1574088_1575114_-|bifunctional-diaminohydroxyphosphoribosylaminopyrimidine-deaminase/5-amino-6-(5-phosphoribosylamino)uracil-reductase-RibD
MYINKAFELVKWTEGQTGMNPAVGCVIVKDDRIVGIGAHLTEGEAHAEVNAIHMAGSHAQGATLYCTLEPCSHHGKTPPCTEKIVAAGISKVVYAASDVTLSSGVKYMRSESIEVEKVECRAIDDFYAPFFTSKTSSLPYVTIKMATTVDGKTADDESISKWITNEKSRAHAHEVRYRMDAIMVGYNTYKKDIPTLDARLYKDKRIKKVIVTNGPFVLNTQDDNDYDRSRLIIVSAIEQHIEGVTVIHVPHLSPEHILKALYNERIRNLLIEGGMQTIRTFIEAKYYNEIHHYIAPKLLGGTSKHQFLTTDTLSSMRDMTHFNLVSVNQFDDDVLLIYRKA
>NC_011999.1|WP_012657359.1|1573460_1574084_-|riboflavin-synthase
MFTGIVEEVGTISQIKQQSDTTVMTINCQEILSDIHIGDSISVNGVCLTVTSFNTQSFTVDIVRGTSAITLFHTMKVGTQVNLERALLPTTRLGGHFVSGHIDTSVSVKRIQHNEKTYIIELECPEKFRRNVIPKGSVAVNGISLTIFELTNSITLNIIPETVRSTMLNTLKAGDKVHIEFDMLGKYILNQTKSSDTLTLSKLEMMM
>NC_011999.1|WP_012657358.1|1572270_1573461_-|bifunctional-3,4-dihydroxy-2-butanone-4-phosphate-synthase/GTP-cyclohydrolase-II
MFDSIEEALQDLKLGKPIIVVDDEDRENEGDLIAITDFMSEETINFMITHARGLVCVPISHALNDKLGLLPMTTDNQDPNKTAFTISIDHKDTTTGISAKERFMTVKALADNNVTLAQFNQPGHIFPLIAQQGGVLRRKGHTEACVDLAKLSGASETGVICEIIKDDGTMARRDDLVIYKEKHELKMITIDAIIDYIKSTKPLVTREAKVHMPTDFGTFQMYGYKEIYSDKEHVAYVKPYKGVPHIRIHSECLTGDVFHSKRCDCGKQLEEAMQHIDEHGGILLYLRQEGRGIGLINKLKAYEKIEQGLDTVEANHALGFRSDLRDYAVAASMLRDLGVHKVEVLTNNPHKIEGLKHYGIEVIERIPHQFQSVDENKNYLETKKQKLGHLLKENLI
>NC_011999.1|WP_012657357.1|1571809_1572274_-|6,7-dimethyl-8-ribityllumazine-synthase
MNYSAKLTGEGLKIAVVTSRFNHFITDRLTEGAIDTLERHGVVKEDIDIFLVPGAFELPFVASKLAQKKKYDAVITLGCVIRGATTHYDYVCNEAAKGIAKAGEYGTPVIFGVVTTESIEQAIERAGTKAGNKGGEAAISAIEMANLNKMMDEL
>NC_011999.1|WP_012657356.1|1570780_1571773_+|proline-dehydrogenase-family-protein
MGITRDFFIKLSENETLNTAAKKYGLALGAHKVVAGTDIETTIESIRALNAKNISATVDNLGEFVFSKEEATAAKNNILEMIQAIYDAGVDAHMSIKLTQIGLDVDPEFCYENVREILMKAYECGNMHVNMDTEDYNHTVQTFEMLDRLKGEFKNIGTVIQAYLFRASEEIDKYQDVRLRLVKGAYKEDASVAYQSKEEIDANYIKIIEQRLLNAKAMTSIATHDHNIIDHVKKFIAQHNLNKDLIEFQMLYGFRSELQVEIANSGYNFCTYVPYGQDWYGYFMRRLAERPQNLQLVYKSIATPEVKKNAGIAAGAAVGIIALSKLFKRK
>NC_011999.1|WP_041636092.1|1569954_1570512_-|energy-coupled-thiamine-transporter-ThiT
MNRERTVILLEIAMMAAFAMVLDFIDSQIKGIFFGLSLSFSMVPVLLLSFRRGVKAGMTAGFLWGLLQIAVGDAAGSIVHPLQGFLDYAFAFTLIGLAGLAGQPVNQVKIVIFTALAVFARYFIHFLSGWVYFGAYAPKGQPAWLYSLVYNGQVALINGVTCIIILVILFTVAPRLFSVANYNKY
>NC_011999.1|WP_012657354.1|1568565_1569660_-|AAA-family-ATPase
MRDLGVYFGTFAPCHVGHLEQIIRAKRENKNALVIVSGYDDDRGDKAGMSLTNRVKAMRELLKDDENVTVVTLDETNIPRYPAGWAPWLDLLKDKIQEQAVSLDLPMESVTFYVGEEEYIEPLDSYFTKAFAKSDVQITKVDRRITGISGTSIRENPILNWDFVTRPFRRFFVKNILVIGTASTGKTTLVRDLARRYSTSYSLEYSREYQTTRQVRDDELDIKDLHTIGIGQFELNRKHIHSPGTRKVFFADTDVMTTKLYTKLYAPKEDYEKIAPVFDYYISLQTWALIIVLPPTTNYVDDGFRDMSMADEKARLDMHQMFLDEIKYQGLEDRMVVLKGESFQEKYEEAHRLVDEILADGKDN
>NC_011999.1|WP_012657353.1|1567817_1568555_-|nicotinamide-mononucleotide-transporter
MFLVKDFKGFTTYEKLFFGLFMLVQVAILVYFRIIDGTTDWLNVVASVSGILCVIMSAKGRLSTFFYGLIQVASYGYISYMHKYYGEVGLQVVFGIFQFVGLYFWIRNMHSDYLTDDPNVQEVDSRGLDVKGWGITAIITAAIYSLVVYLLVSRTDANQPFVDGIATSLSLVGQTLMTLRYKEQWLFWILINIVSIFLWARGMFQNGAIDAAGVTMVVMWIGFLINSIYGYYYWKKLQHVNVENR
>NC_011999.1|WP_012657352.1|1567039_1567771_+|IS3-family-transposase
MIKEIINKHKNRIGYRTVTDELRELGFVVNHKKVLRIMRENNLLCTKFKHRNRTYKSYKGKVGKTAKNKLNRRFITNRPYQKLLTDVTQFNIKNGTKLYLSTIFDVCSKEIISYSISKRPTLKFVMESLLKAINVIPDLPCRTTIHTDQGWQYQHKSWVQTLKKNRIIQSMSRKGNCLDNSPMENFFGILKQEMFYGETFDSYDELEEEIIDYMEYYNLVRKKRKLKSKTPVEYRNLALMKVA
>NC_011999.1|WP_041636090.1|1566377_1566896_+|helix-turn-helix-domain-containing-protein
MNKKHDLDFKLKLIKEYKEGNIGYNSLSNKYDIDPSQLKTWTYQFDTFGIDGLISSMTRKKYSTDEKLRIIQYRITNQLSYKETARIFEITNPTLIAQWQMKYNQYGILGLESKPKGRASKTMKNKKVDNTSLNESERQELIRLREENRRLEIAIALEKKLQSLARKNQTKK
>NC_011999.1|WP_041636463.1|1575682_1576915_-|imidazolonepropionase
MNDLIIQNISELILPKKTDKPLKGAELADLKIIENGTVVIKDGKIVYAGEFNDEYVAGETIEAKGKTVSPALVDAHTHLVHGGSREHEMSLKRQGVSYLEILEQGGGIHSTVKATREASEDELFDKAEHELLRMIHHGVLSVESKSGYGLSLEHELKQLRVSKRLQEKYGINMKHTYLGPHAVPKDKDSDVFIKECINDLEKVKDLADFADIFCETSVFTIEQSREYMQAAKEHGLPVKIHADEIDPLGGLELAIEEHAISADHLVAASEKGKEMLKDSDTVAVLLPGTTFYLDKNEYADARGMLDNNGAIAIATDYNPGSCVTSNLQMVMSIAALKLKLSPKEIWNAVTVNAAKAIGLDAGTIDAGDEANIVVWHAKNHEYIPYQYGVNHAEKVIHKGKVIVENDFKLK
>NC_011999.1|WP_041636093.1|1576933_1578583_-|urocanate-hydratase
MGDIRAKKGLEIECKGWEQEAVLRMLYNNLDPEVAEHPEDLVVYGGIGKAARNWESFDAIVDSLRNLEKDETLLVQSGKPVAVFKTHDQAPRVLLSNSVLVPKWANWEHFNELDKKGLMMYGQMTAGSWIYIGSQGIVQGTYETFGELANQHFDGDLAGTITLTAGLGGMGGAQPLAVTMNGGVVIGIDVDESRIDKRIETRYCDVKTHSVDEAIRLATEAKDKKEALSIGLVGNAVDIYKELLEKNFKVDIVTDQTSAHDPLNGYVPVEYTFEETVRMRKENPEEVVRLAKKSMAKHVEYMLEYKKRGAVAFDYGNNIRQVAFDEGVTDAFSFPGFVPAYIRPLFCEGKGPFRFAALSGDPKDIERADEEMRKLFPDNKKLMRWLDLASEKIAFQGLPSRIAWLGYGERAKMGLALNKLVETGEISAPIVIGRDHLDAGSVASPNRETESMQDGSDAVGDWAVLNALINTAAGGSWISFHHGGGVGMGYSLHAGMVVVADGTKNAEERLQRVLTTDPGMGVVRHVDAGYDIAVNVAKEKGINVPMLDK
>NC_011999.1|WP_012657363.1|1578714_1579602_+|LysR-family-transcriptional-regulator
MKILHFEYYIAVVEHQSFTRASAYLHISQPSLTAAIKKLEAEIGYKLLTRSTKEIKITERGILFYQYAKDIVHKYQQTVEQMYDLNYSNTPKIKVGILESASKWVSAVIAQHKGHYTDQHYMIREILTTDAITQAITNYDVHIALSNEQLIHDDIISLPLYSEDYILTAPKDTFNNKRSVNLSDLPLILPNDSFQVRKHLNDYFLRHNIRPHIVLEVDRFETALNYVHERVGYAVIPKIYYQSHNASHLNAITIRPNISRTIYINYHKKRKHSTRVLSLIDCFIKYWDYGALQKT
>NC_011999.1|WP_012657364.1|1579561_1580497_-|formimidoylglutamase
MYSEADRTLWHGRIHDNDNHAHFTNSQLVQVVDAEGELTERFDVGILGYAVDRGVYLNQGRVGTKQGPDAIRTKFGNLPLMHDLSIADFGNVTTEEKFVEDVQHEYAELIDKTNDYAKFHLLIGGGHDISYAHFKGLKALYPEQSIGVINIDAHFDLRDSEYGTSGTGFKQILDEDADAGYLVLGLQEAGNTQHLFEVAEQYDVKYVLAEDIDYDTTDEIIQSFIEQYDIIMLTLCLDVIDSAFAPGVSAPCSFGLTPQQVERLIRAVLSYGKTRHLSIAEMNPEYDIDGRTAKLVGHIMFFAVHRNPSIL
>NC_011999.1|WP_012657365.1|1580489_1581941_-|FAD/NAD(P)-binding-protein
MRIAIIGAGVGGVSVMKYLHKEKKLKAEITVFDDKKYMGSGRAFQYDDPELLMNYPGNLISMKPNKQRDFIDWIQKSNVNKEIHLDEAENTSANRYYSRQLFGKYMREHFEKFANKKNVSIITDHARNVEFIGQEYVVSTQNGTYYFDAVFLSPGQFGPMDPYHLEGTTGYYKWPYPLHEKSIEANKDYAVIGTGLSSLDIVRYFIAHSTNKLALISRDGKVQSVRGKMQKVKFKYITHKKLEKIKVAHHGYIPLEELVERFKKELDRLDLDVEKLRINRLNPVRALNFDLSHPEEVGLMQSFVLEIVHIASYIWPFMTREDKAAYRKHYAPILDDYANPMPEGTAEELLDTLSSGRVEIYSGITDIEYKYNKFRIHTKDKELRVHYVFNATGPAKAYKDATEPNPLIENLVNQDLLIEHPDGGFYVTPIRNQVITREGVMSRFFMLGQKTSGVNYLDNGIMELIDEAKRTVKALAEEERLDV
>NC_011999.1|WP_012657366.1|1582056_1583187_+|betaine/proline/choline-family-ABC-transporter-ATP-binding-protein
MLEMNNVSKVYKGGKKAVSDLNISIKQGEFIAFIGTSGSGKTTAMRMINRMIEPTSGTITLDGKNIKELNPVQLRRKIGYVIQQIGLLPHMTIRDNITLVPKLLKWSEEDKNKKAEELIQLVDLPLSYLDLYPAQLSGGQQQRIGVVRALAADQDIILMDEPFGALDPLTRDTLQDLVKELQVKFNKTFIMVTHDMDEAIKLADRIVIMSNGEVVQLDTPNNILRRPANDFVRDFIGENRLIQTTPNVKTVDEAMVKPISVTAEKSIGEAIQIMRERRVDTLLITDNDNVLVGYVDIEDLSEAAKKSLSLSRIMNHNVYFVRSGVYLQDTVRTILKRNIRLIPVLDKHDRLLGVITRANLVDIVYDTIWGEALEEV
>NC_011999.1|WP_012657367.1|1583188_1583833_+|ABC-transporter-permease
MLAFLQENQAELLEKTWEHISISLLSLLAAIIVAVPLGIVLTKSDKLAKIVLSITSVLQTVPSLAILAMMIPFFGIGTVPAVIALFLYVLLPILNNTYLGIQSVNKDAREAGRAMGMTQNQLLRMVELPLAVPVIMSGIRLSAVYAISWATLASYIGAGGLGDFIFNGLNLYQPKLIIVGAVVVTLLALVTDFVLAYIEKITTPRGLVVSKGEK
>NC_011999.1|WP_012657368.1|1583833_1584733_+|osmoprotectant-ABC-transporter-substrate-binding-protein
MKKLLILLSCLLVLSGCGQNNQKETVKIASVYTTESQILANMIKLLVEKETDHPVELINNLGSGTVVHQAMMRGDANVSSARYTGTDLTGPLGKAPITDPDKARSVVVKGFEERFDQHYFDSYGFENTYAFMVTKETAKKYNLKTVSDMKKVAQNLRAGVDSSWMKRKGDGFEAFKKTYGFDFKDTKPMQIGLVYEAVNAGKMDVVLGYTTDGRIQSYDLVVLKDDLQFFPPYDANPVATNELLKKDPKIKKLLESMKDQISTEQMQKLNYEVDNNLKEPAVVAEAYLKSHNYFKGGAK
>NC_011999.1|WP_012657369.1|1584732_1585425_+|ABC-transporter-permease
MENLNTFEQFIHYFQDNAGYVFQLFLEHFLISIYGVLLAAIVGIPIGVWIARHRRLVAPVISVANIIQTIPAIALLALLMLAMGLGKKTVIMAVFLYALLPIIKNTYTGIKAVDEHIVDAGRGMGMTKRQLLTMVELPLSLSVIIAGIRIALVIAIGVTAIGSFIGAQSLGDIIIRGTNATDGTSIILAGALPTALMAVLADIILGLIERRLDPTKRKKLNQAAPSTENE
>NC_011999.1|WP_012657370.1|1585488_1586349_+|hypothetical-protein
MKSRQLLSLLLGSTLIFTACGQETKKTEDTKSEEKKAETSTESKSSETASEKKSSEVKDAEALVAKAQEKGQDIKSYHANLDTQLKSGSDTSNVKMEMSVDDAERTKISTDMQNQSMDMYIFDKKVIITQDGQNFIDATSAMEDQVKNQLDQLDYNSALETLNAYKDSEFKATDKGYELTKSFKGLDEYKQLSEATGSEDAVKALEGQLKDIDGKATIIFDKDFMMTKTITDINMTVKDKKMNTKTTATYDQYNQVKAIEIPAGAKNAQSIEELQKSEETSTEKAS

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Crispr_ID: NC_011999_3

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_011999_3

1843190-1843286

Orphan

Consensus_repeat	Method
TTTGTCCTCTTTCACTTGTCTAGGTGGCGGACTTCT	CRISPRCasFinder

1 spacers

The CRISPR arrays of NC_011999_3

>merge|NC_011999|3|1843190-1843286|CRISPRCasFinder
TTTGTCCTCTTTCACTTGTCTAGGTGGCGGACTTCTGTGTAGTTCGTCACCTACAGTTGGCTTTGTCCTCTTTCACTTATCTAGGTGGCGGACTTCT

>NC_011999|3|3|1843190-1843286|CRISPRCasFinder
TTTGTCCTCTTTCACTTGTCTAGGTGGCGGACTTCT	GTGTAGTTCGTCACCTACAGTTGGC
TTTGTCCTCTTTCACTTATCTAGGTGGCGGACTTCT

Protein	Signature genes	Signature genes Name	Protein_function
NC_011999.1\|WP_015912216.1\|1852360_1853209_+\|VOC-family-protein	unknown	unknown	gnl\|CDD\|225312
NC_011999.1\|WP_015912212.1\|1847948_1849388_-\|polyphosphate--AMP-phosphotransferase	unknown	unknown	gnl\|CDD\|274736
NC_011999.1\|WP_015912206.1\|1842336_1842882_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|374138
NC_011999.1\|WP_041636184.1\|1841170_1841677_-\|GNAT-family-N-acetyltransferase	unknown	unknown	gnl\|CDD\|366181
NC_011999.1\|WP_015912217.1\|1853362_1854220_-\|MurR/RpiR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|224651
NC_011999.1\|WP_015912198.1\|1836559_1837309_-\|ABC-transporter-permease	unknown	unknown	gnl\|CDD\|372253
NC_011999.1\|WP_015912202.1\|1839451_1840183_-\|DUF3169-family-protein	unknown	unknown	gnl\|CDD\|371493
NC_011999.1\|WP_015912218.1\|1854360_1855062_-\|GH32-C-terminal-domain-containing-protein	unknown	unknown	gnl\|CDD\|224536
NC_011999.1\|WP_015912200.1\|1838301_1838961_-\|response-regulator-transcription-factor	unknown	unknown	gnl\|CDD\|223816
NC_011999.1\|WP_015912208.1\|1844013_1844628_+\|amino-acid-transporter	unknown	unknown	gnl\|CDD\|224198
NC_011999.1\|WP_015912211.1\|1846978_1847734_+\|CPBP-family-intramembrane-metalloprotease	unknown	unknown	gnl\|CDD\|376806
NC_011999.1\|WP_015912210.1\|1846481_1846766_-\|co-chaperone-GroES	unknown	unknown	gnl\|CDD\|178988
NC_011999.1\|WP_015912199.1\|1837305_1838214_-\|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|224054
NC_011999.1\|WP_015912215.1\|1851277_1852141_-\|LPXTG-cell-wall-anchor-domain-containing-protein	unknown	unknown	gnl\|CDD\|236766
NC_011999.1\|WP_015912201.1\|1839076_1839439_-\|hypothetical-protein	unknown	unknown	unknown
NC_011999.1\|WP_041636183.1\|1840179_1840383_-\|helix-turn-helix-transcriptional-regulator	unknown	unknown	gnl\|CDD\|224393
NC_011999.1\|WP_015912209.1\|1844802_1846422_-\|chaperonin-GroEL	unknown	unknown	gnl\|CDD\|234573
NC_011999.1\|WP_015912207.1\|1843307_1843802_-\|hypothetical-protein	unknown	unknown	unknown
NC_011999.1\|WP_015912203.1\|1840580_1840934_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|274982
NC_011999.1\|WP_015912205.1\|1841961_1842330_+\|hypothetical-protein	unknown	unknown	unknown

Protein	Function_ID	Function_description	E-value
NC_011999.1\|WP_015912216.1\|1852360_1853209_+\|VOC-family-protein	gnl\|CDD\|225312	COG2514, COG2514, Predicted ring-cleavage extradiol dioxygenase [General function prediction only].	1.46606e-76
NC_011999.1\|WP_015912212.1\|1847948_1849388_-\|polyphosphate--AMP-phosphotransferase	gnl\|CDD\|274736	TIGR03708, poly_P_AMP_trns, polyphosphate:AMP phosphotransferase. Members of this protein family contain a domain duplication. The characterized member from Acinetobacter johnsonii is polyphosphate:AMP phosphotransferase (PAP), which can transfer the terminal phosphate from poly(P) to AMP, yielding ADP. In the opposite direction, this enzyme can synthesize poly(P). Each domain of this protein family is homologous to polyphosphate kinase, an enzyme that can run in the forward direction to extend a polyphosphate chain with a new terminal phosphate from ATP, or in reverse to make ATP (or GTP) from ADP (or GDP). [Central intermediary metabolism, Phosphorus compounds].	5.65317e-154
NC_011999.1\|WP_041636184.1\|1841170_1841677_-\|GNAT-family-N-acetyltransferase	gnl\|CDD\|366181	pfam00583, Acetyltransf_1, Acetyltransferase (GNAT) family. This family contains proteins with N-acetyltransferase functions such as Elp3-related proteins.	5.22381e-20
NC_011999.1\|WP_015912217.1\|1853362_1854220_-\|MurR/RpiR-family-transcriptional-regulator	gnl\|CDD\|224651	COG1737, RpiR, Transcriptional regulators [Transcription].	9.29963e-56
NC_011999.1\|WP_015912198.1\|1836559_1837309_-\|ABC-transporter-permease	gnl\|CDD\|372253	pfam12679, ABC2_membrane_2, ABC-2 family transporter protein. This family is related to the ABC-2 membrane transporter family.	9.76387e-05
NC_011999.1\|WP_015912202.1\|1839451_1840183_-\|DUF3169-family-protein	gnl\|CDD\|371493	pfam11368, DUF3169, Protein of unknown function (DUF3169). Some members in this family of proteins are annotated as membrane proteins however this cannot be confirmed. Currently there is no known function.	4.52484e-09
NC_011999.1\|WP_015912200.1\|1838301_1838961_-\|response-regulator-transcription-factor	gnl\|CDD\|223816	COG0745, OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription].	3.15667e-69
NC_011999.1\|WP_015912208.1\|1844013_1844628_+\|amino-acid-transporter	gnl\|CDD\|224198	COG1279, COG1279, Lysine efflux permease [General function prediction only].	5.35869e-58
NC_011999.1\|WP_015912211.1\|1846978_1847734_+\|CPBP-family-intramembrane-metalloprotease	gnl\|CDD\|376806	pfam02517, Abi, CAAX protease self-immunity. Members of this family are probably proteases (after a isoprenyl group is attached to the Cys residue in the C-terminal CAAX motif of a protein to attach it to the membrane, the AAX tripeptide being removed by one of the CAAX prenyl proteases). The family contains the CAAX prenyl protease. The proteins contain a highly conserved Glu-Glu motif at the amino end of the alignment. The alignment also contains two histidine residues that may be involved in zinc binding. While they are involved in membrane anchoring of proteins in eukaryotes, little is known about their function in prokaryotes. In some known bacteriocin loci, Abi genes have been found downstream of bacteriocin structural genes where they are probably involved in self-immunity. Investigation of the bacteriocin-like loci in the Gram positive bacteria locus from Lactobacillus sakei 23K confirmed that the bacteriocin-like genes (sak23Kalphabeta) exhibited antimicrobial activity when expressed in a heterologous host and that the associated Abi gene (sak23Ki) conferred immunity against the cognate bacteriocin. Interestingly, the immunity genes from three similar systems conferred a high degree of cross-immunity against each other's bacteriocins, suggesting the recognition of a common receptor. Site-directed mutagenesis demonstrated that the conserved motifs constituting the putative proteolytic active site of the Abi proteins are essential for the immunity function of Sak23Ki - thus a new concept in self-immunity.	1.67943e-10
NC_011999.1\|WP_015912209.1\|1844802_1846422_-\|chaperonin-GroEL	gnl\|CDD\|234573	PRK00013, groEL, chaperonin GroEL; Reviewed.	0
NC_011999.1\|WP_015912199.1\|1837305_1838214_-\|ABC-transporter-ATP-binding-protein	gnl\|CDD\|224054	COG1131, CcmA, ABC-type multidrug transport system, ATPase component [Defense mechanisms].	4.73334e-79
NC_011999.1\|WP_015912215.1\|1851277_1852141_-\|LPXTG-cell-wall-anchor-domain-containing-protein	gnl\|CDD\|236766	PRK10811, rne, ribonuclease E; Reviewed.	0.00129087
NC_011999.1\|WP_041636183.1\|1840179_1840383_-\|helix-turn-helix-transcriptional-regulator	gnl\|CDD\|224393	COG1476, COG1476, Predicted transcriptional regulators [Transcription].	5.47961e-26
NC_011999.1\|WP_015912210.1\|1846481_1846766_-\|co-chaperone-GroES	gnl\|CDD\|178988	PRK00364, groES, co-chaperonin GroES; Reviewed.	9.2799e-41
NC_011999.1\|WP_015912218.1\|1854360_1855062_-\|GH32-C-terminal-domain-containing-protein	gnl\|CDD\|224536	COG1621, SacC, Beta-fructosidases (levanase/invertase) [Carbohydrate transport and metabolism].	7.61533e-30
NC_011999.1\|WP_015912203.1\|1840580_1840934_-\|hypothetical-protein	gnl\|CDD\|274982	TIGR04104, hypothetical_protein, cxxc_20_cxxc protein. This small, uncommon, poorly conserved protein is found primarily in the Firmicutes. It features are pair of CxxC motifs separated by about 20 amino acids, followed by a highly hydrophobic region of about 45 amino acids. It has no conserved gene neighborhood, and its function is unknown.	9.00208e-23
NC_011999.1\|WP_015912206.1\|1842336_1842882_+\|hypothetical-protein	gnl\|CDD\|374138	pfam15814, FAM199X, Protein family FAM199X. This family of proteins is found in eukaryotes. The function of FAM199X is not known.	0.00982785

>NC_011999.1|WP_015912206.1|1842336_1842882_+|hypothetical-protein
MKTLKICGILLLLLMIPETTDAGGTQSSSSSGSSSSTSSSSSARSSTTSSAAVNASRINTMSRMNNTSRMNSSQNLQRAKANAVTLTPPVRNKMTQPLKYQAAHNQFLNNQIFYGAMYGHSSNVQRQQALIRQQLGNRKAYTISVKRNGRERLYIVSKEIYDRVESGDSVHIKNGVVTLKE
>NC_011999.1|WP_015912205.1|1841961_1842330_+|hypothetical-protein
MKRLSYIVILTLLLAACGNAKEKEAPDASGENVKKYDLVYAEVLNNGSESKMSMEVGYKDNKKLKSERFDTENVTEHILKDESAKPYILIKKNDVHIFRQPYIIFDNEGEFDAKVKKKSVVE
>NC_011999.1|WP_041636184.1|1841170_1841677_-|GNAT-family-N-acetyltransferase
MIQPCTIEDKQALQHIAYQTFDETFRAQNKKENIDHYLKTAFTDEKVERELSNPHSFFYFIFHEEQLAGYLKLNIKDAQTEPFDEHHLEIERIYILKQFQKHGLGQSLYQHALQKARALSCEHIWLGVWEKNTNAIDFYQKMGFTKVDQHAFFMGDDEQIDIIMLKNI
>NC_011999.1|WP_015912203.1|1840580_1840934_-|hypothetical-protein
MKCVHCNYKFTFKERMKVGWKPSTDTIVICPKCGGRQYISNKRMAKSYGLILLVELILIIAAPLIKIPIPLLTVLMIIALALVIVLLPLSLKLVAEKDGLLEEQFREMEKKQKRKSL
>NC_011999.1|WP_041636183.1|1840179_1840383_-|helix-turn-helix-transcriptional-regulator
MKNRLKELRAREGYNQTQLAKLAHVSRQTISLIERDDFMPSILTAVRIARIFNEQVEDIFIFEEDEL
>NC_011999.1|WP_015912202.1|1839451_1840183_-|DUF3169-family-protein
MSKKKNSGFLKIMIGMAFGAIAGYSIPALYDAVTSLQATYNIRILWYIVPILFVIALYLYFKSIHQFKAMNSDINLSEDDRFIYQVTYHNKASANVANAYHILLLSLCLSITILIEPETLHIIIFAVYFIACAIFYTFISKQTAKVLAAYPTITNSDVSIEFGDPNLMEKVIDGIDEGERLVMLRSLSKTYEIMILMLSVILMLLGIYQAATGENQYLAMFAIAAVLIYSTVVYYKKNEEFNR
>NC_011999.1|WP_015912201.1|1839076_1839439_-|hypothetical-protein
MRHIKRKPKQFVLIVILTLVYSSIHLYGNDHILWSIVYCLLIFIMLMTFFITTSDEEEINEQLDQEVKRLNMPRERLYQVTGYNRYEVSKSEDGQIIFWIPMSKKKVLLKKLKGMEPEQE
>NC_011999.1|WP_015912200.1|1838301_1838961_-|response-regulator-transcription-factor
MAHILIIEDDRDIADLLALTLSGHYDVTLAHDGKEGYMYIKEQAFDLILLDLMMPYMNGETLLGEIKHHTNTKVIIITAKHELEHKVNLLTLGADDYITKPFYQEEVLARVMVQLRNIEKGSSLITHRALKLDTEKREVTLNDKGIQLTNSEFDILTILMKHPEVPLSKQKIFNALGNGTYVGDDNTVSVHVSNIRKKFSQITDEPYIKTVWGIGFMLI
>NC_011999.1|WP_015912199.1|1837305_1838214_-|ABC-transporter-ATP-binding-protein
MESIIRTHQLEKTFKTNKGLKPLDFQLFKGEICAIIGKNGAGKSTFFKLLAGQLQPTRGEMAFFDYAAAESNRARKRMGFMIESPEFFAELTAYENLNYFRLQRGISSKDAVKRVIEAVDLSKYPATRFKEYSMGMKQRLGLALTLMTGPDCLVLDEPTNGLDAEGISDIRKLLLKLNKEQDITILISSHILSELQLVATRFLFIDKGQVIEDISREELHNRNRKSLKLIVNHPSRAARVLEESFTDLKYSVLPDNTLKLDNHVEDAAQINRILMQHDIDVKEIMTETNSLEDYFLSLGVTP
>NC_011999.1|WP_015912198.1|1836559_1837309_-|ABC-transporter-permease
MMNYMRSEAYKLLRTKGIYITYALCIMLLIIAALTLYYFGHNGEYFPYYRADFYYNNVFGMWLFIVMIGAVINSFLTNKESKRVLKQSISYGISRATIYFSKYLVALIAFTILCILGTIVLLTCGQLFFPKDTPAVEEFLLSLINFSPIILGAFSLVHALNMVIRRETIAIVSFIFILLGTSTVAYILTKINKAFDVFYNLTPKVLSDRVLSEFMNHNVELSADFWISSLIITTLSLFIGYRLFKKEDF
>NC_011999.1|WP_015912207.1|1843307_1843802_-|hypothetical-protein
MTYEAMFKRYNKMRRLSNDKENIEALLKQYKAFEIPVHSIHHDDYHNDEEVDPLYIYKLFHISDKHALNKIMDAAYKDKGDDTYPLGSELTYRSLIGKHNSGRGVSIVLESKDGKKVSNFKIYGQAQKLSELLLCYIPFEAMTEDIRSSDFQYFLECLDGNGFL
>NC_011999.1|WP_015912208.1|1844013_1844628_+|amino-acid-transporter
MIQSILHGFLLAFGLILPLGAQNVFVFNQGANHKSFKKIIPVVVIAGLCDTLLILLAVFGVSLLLNQYPALQLIIYSIGFIFLLYMAWSLWHESPSSKSDSTPMSAKKQISFALSVSLLNPHAIMDTIGVIGTNAAMYQHAEKIVFTITTISVSWIWFISLGLIGKLVGNIDQEGKFILALNKVSSIIIIAVALLIAKNIVEII
>NC_011999.1|WP_015912209.1|1844802_1846422_-|chaperonin-GroEL
MVKEIKFSEDARRAMLAGVDKLADAVKVTLGPKGRNVVLDKKFVAPLITNDGVTIAKEIELEDPYENMGAKLVAEVANKTNEIAGDGTTTATVLAQAMIQEGLKNVTSGANPVGIRQGIDKAVAVALEELAAISKTVSSKEEIAQVGSISAADEEIGQFISEAMEKVGNDGVITIEESKGFKTELEVVEGMQFDRGYASPYMVTDSDKMIADLENPYILITDKKISSFQDILPILEQIVQTSRPILIVAEDVDGDALTNIVLNRLRGTFTAVAVKAPGFGDRRKAMLEDLAILTGGQVITDDLGLDLKDTTVEMLGNAGKVHVTKDNTTIVEGRGDASNIDARVGQLKAQIEETTSEFDKEKLQERLAKLAGGVAVIKVGAATETELKERKLRIEDALNSTRAAVEEGIVAGGGTALVSIYNKVAAVEATGDVATGVKIVLKALEAPIRQIAENAGLEGSVIVEKIKHAETGVGYNAATDEWVNMIDAGIVDPTKVTRSALQNAASVAAMFLTTEAVVAEMPEENPTPDMGMGGMPGMM
>NC_011999.1|WP_015912210.1|1846481_1846766_-|co-chaperone-GroES
MLKPYGNRVVIQKTERETTTASGIVLTDSAKEKTNEGTVVAVGTGRILNNGERVEIGVSVGDRVVYEPFGGTEVKTGDESYIVLKEEDIIAIVE
>NC_011999.1|WP_015912211.1|1846978_1847734_+|CPBP-family-intramembrane-metalloprotease
MKHNRKWINILTVLLYIGSQLFVLIPTSIFLKQGLDNDAAFLKAIPYYVGSFVVASILVIYINTKINNKTRVERSVKTDTLSTIGLIVGGLFISLFTQMMLGMVNTYILNQPMESQNTTQIMGIAKQAPIFIILIAIVGPILEEFVFRKVIFGELYELIKGNRAVAFTISVLISGFIFSAAHSDFNHTLIYMGMSVVFSGLYVLSNRIIVPIAAHMLMNGFVVLMQVVFADKVIEAQKQLEQANLIWHLFN
>NC_011999.1|WP_015912212.1|1847948_1849388_-|polyphosphate--AMP-phosphotransferase
MTKIDKQLQLTTAELVRKTHEAGIPVMIVFEGIPASGKSRLSNELLLTLDAKYTNFYATKRPDEELLRYPFLYPYWNNIPKKGGVTLFFRSWYAQKLDFEEHGYKKDIIKDYDLLTQEIKGFESMLSDDGYVIIKFYLSVNEQKRQEHIEQTKKNPLTRWKAQEYEASIPTKVYQDGMIDLMKATEEIAPWTHIDYTERGKAVNEMYEVIIKRLEKALKAKEKSKQDERDGAFTEDFTTDMFEDTSDNMSKAEYKELLPKLQARIRELQYALYERKIPLMLVYEGMDAAGKGGNIKRVRESLDPTGYEVNAISAPTETELSYHYLWRFATDVPRSGHIEIFDRSWYGRVLVERVEGFATNKEWQRAYDEINKFEKALTIEGAIVIKFFLVLDKDEQLKRFEERQVTPEKQWKITDEDWRNREKWDLYLEASKDMIDNTTTEHAPWVIIPANNKRAARIKALKTIISVCEERLWNVKKLW
>NC_011999.1|WP_015912215.1|1851277_1852141_-|LPXTG-cell-wall-anchor-domain-containing-protein
MYKFKVKAVAALVCMLGLSTQNATLSEAADNSVTAEQPSSEQVESIKKESSLKSAEDKSPESPVIEIVSTEIIKEDETTEMPTTEAPTTEIPSKEQTPTTELPSVEVDQPTERPTTEVPTTEVPTTEVPTTEQPAPAFPSHDDADSTPPKYDDNDYSAGVVPPSPGTIDIPELPDTPVSPVELSDSESEYSSLEEDDDLLSIKPGKFKPTDGEAYYAALDKQVWDLVTREIGKSKKSHQDKDSKATSKQKQKVKKHAKLPDTGENVFMYVLASVSLLLSGLILLRKS
>NC_011999.1|WP_015912216.1|1852360_1853209_+|VOC-family-protein
MERQFFSKDTHIGAVHLNVNFMDNSVKFYHEILGMDIIEHTPTFSSLGVNDSVLIYLYQTNHARVQTAGLFHFALLVPSRAALGNIFYHLIKTEYPLAGASNHDVSEAIYLQDPEGNGIEIYRDVPSNEWQFEPNGNIVMGTSEMDYAAVIEANHNRPFDGMPKDTIIGHMHLSVIDLNQSIAFYNELFGLDVMTRYGSQAAFMATAGYHHHLGLNTWQHQTERARLDYPGLRKFDLNIPNEEDLQHFLETLSEKGLTQSKDENSNIIYDPSGIGIRIMTKN
>NC_011999.1|WP_015912217.1|1853362_1854220_-|MurR/RpiR-family-transcriptional-regulator
MYSVLGQITKMYDSFTPVEKRIADVVIEYPEKVVNLPIKEIAHLSNTSEAAIVRFSKRLGLSGIKVVKVELARELHTIADKKVPTKIELTDDEEVMKEKVFNNTIQALYNTEKVISAKVIDEAAQAITSAKRVMIFGVGNSRVVATDLHVKLMNIDQSAILATDLLSAITLLGHYEAGDVLFVTSETSKNKVITDICKYAKEKGIKIILLTQKFSSPAIRMADIVLAMAKEENEINLGYMTVRTAQLTIVDVLYLRVCAYLKDTVLSNMQNLNETRKITHEQENL
>NC_011999.1|WP_015912218.1|1854360_1855062_-|GH32-C-terminal-domain-containing-protein
MKESQVSSLTLQELNELEAQVGSKLNVYPSSFNYDITDHGFDYQPVAFMMDEQERCLLIGRIGDTLATPRIVSIEDGQLRQRPLLPSNRRGKLETAEGYATRKNVRLHPYEGDNYELVAEIIENNALEYILELRVSRKERTVLIYETEKRIFTVDRSDSGVIDELYTKFIALHEPLTKLHCIVHKQTIEIFINDGEAVMSMRINTSESADGIRTSAVHGDVYLKLWKYDLKEA

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

505679 : 514324

Acinetobacter_phage(33.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_012656385.1\|505679_506588_-	diacylglycerol kinase family lipid kinase	A0A1V0SBJ0	Catovirus	3.2e-11	24.5
WP_041636312.1\|506673_508155_-	peptide MFS transporter	A0A0P0IY73	Acinetobacter_phage	3.6e-73	37.4
WP_012656387.1\|508469_509984_-	peptide MFS transporter	A0A0P0IY73	Acinetobacter_phage	7.5e-74	36.9
WP_086038242.1\|510142_510643_-	NADPH-dependent 7-cyano-7-deazaguanine reductase QueF	E7DN65	Pneumococcus_phage	1.2e-49	65.1
WP_012656389.1\|510649_511507_-	DMT family transporter	NA	NA	NA	NA
WP_012656390.1\|511866_512256_+	class Ib ribonucleoside-diphosphate reductase assembly flavoprotein NrdI	A0A2H4J545	uncultured_Caudovirales_phage	2.5e-34	54.5
WP_012656391.1\|512218_514324_+	class 1b ribonucleoside-diphosphate reductase subunit alpha	A0A2H4J2N6	uncultured_Caudovirales_phage	0.0e+00	82.2

DBSCAN-SWA_2

570732 : 578649

Staphylococcus_phage(57.14%)

transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_148184246.1\|570732_571002_-\|transposase	IS3 family transposase	A0A0N9SIX5	Staphylococcus_phage	1.3e-10	75.0
WP_157821003.1\|571230_571371_+	hypothetical protein	NA	NA	NA	NA
WP_041636326.1\|571599_571821_+	hypothetical protein	A0A0N9SHA3	Staphylococcus_phage	2.2e-14	59.4
WP_148184248.1\|572049_572307_+	hypothetical protein	NA	NA	NA	NA
WP_012656439.1\|572528_573092_+	DUF5067 domain-containing protein	H9A0K2	Staphylococcus_phage	3.5e-16	34.4
WP_157819663.1\|573359_573521_+	hypothetical protein	NA	NA	NA	NA
WP_041635839.1\|573610_573865_-	hypothetical protein	NA	NA	NA	NA
WP_012656440.1\|574042_574765_+	type I 3-dehydroquinate dehydratase	W6LP76	Streptococcus_phage	4.6e-13	27.7
WP_012656441.1\|574834_575368_+	nitroreductase	NA	NA	NA	NA
WP_012656442.1\|575410_575734_-	thioredoxin family protein	A0A1X9I9P5	Staphylococcus_phage	9.2e-06	30.6
WP_012656443.1\|575861_576215_+	Spx/MgsR family RNA polymerase-binding regulatory protein	M1PLC0	Streptococcus_phage	1.3e-16	43.7
WP_012656444.1\|576288_576657_+	glycine cleavage system protein GcvH	NA	NA	NA	NA
WP_012656445.1\|576724_577114_+	topiosmerase	NA	NA	NA	NA
WP_041635840.1\|577085_577397_+	thioredoxin family protein	NA	NA	NA	NA
WP_148184250.1\|577542_578649_+	ATP-binding cassette domain-containing protein	G3M9Y6	Bacillus_virus	3.3e-26	33.3

DBSCAN-SWA_3

739939 : 748328

Synechococcus_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_041635867.1\|739939_740422_+	5-(carboxyamino)imidazole ribonucleotide mutase	A0A2P0VNU7	Tetraselmis_virus	1.7e-19	43.4
WP_012656596.1\|740408_741527_+	5-(carboxyamino)imidazole ribonucleotide synthase	NA	NA	NA	NA
WP_012656597.1\|741523_742225_+	phosphoribosylaminoimidazolesuccinocarboxamide synthase	A0A0E3F9V5	Synechococcus_phage	8.0e-47	41.6
WP_012656598.1\|742226_742487_+	phosphoribosylformylglycinamidine synthase subunit PurS	NA	NA	NA	NA
WP_012656599.1\|742486_743149_+	phosphoribosylformylglycinamidine synthase subunit PurQ	NA	NA	NA	NA
WP_012656600.1\|743151_745338_+	phosphoribosylformylglycinamidine synthase subunit PurL	A6N228	Microbacterium_phage	9.6e-139	38.1
WP_041635868.1\|745316_746735_+	amidophosphoribosyltransferase	A0A1B1ISH6	uncultured_Mediterranean_phage	2.3e-48	28.5
WP_012656602.1\|746737_747760_+	phosphoribosylformylglycinamidine cyclo-ligase	R9TMC7	Synechococcus_phage	5.1e-58	39.8
WP_012656603.1\|747761_748328_+	phosphoribosylglycinamide formyltransferase	M4QRX9	Synechococcus_phage	1.2e-29	41.1

DBSCAN-SWA_4

977329 : 1065189

131

Staphylococcus_phage(38.46%)

tRNA,portal,capsid,integrase,tail,terminase,head,holin

attL 997810:997826|attR 1044940:1044956

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_012656793.1\|977329_978859_+\|tRNA	tRNA (N6-isopentenyl adenosine(37)-C2)-methylthiotransferase MiaB	NA	NA	NA	NA
WP_012656794.1\|978861_979287_+	YlbF family regulator	NA	NA	NA	NA
WP_012656795.1\|979376_981917_+	DNA mismatch repair protein MutS	E3T5Q7	Cafeteria_roenbergensis_virus	4.2e-45	23.7
WP_012656796.1\|981926_983828_+	DNA mismatch repair endonuclease MutL	A0A1B2LRQ5	Wolbachia_phage	3.5e-60	31.7
WP_012656797.1\|983827_984370_+	glycerol-3-phosphate responsive antiterminator	NA	NA	NA	NA
WP_012656798.1\|984503_985322_+	aquaporin family protein	NA	NA	NA	NA
WP_012656799.1\|985340_986834_+	glycerol kinase GlpK	NA	NA	NA	NA
WP_012656800.1\|986854_988528_+	glycerol-3-phosphate dehydrogenase/oxidase	NA	NA	NA	NA
WP_012656801.1\|988656_989553_+	alpha/beta hydrolase	A7XCB7	Tanapox_virus	5.2e-06	27.4
WP_012656802.1\|989545_990484_+\|tRNA	tRNA (adenosine(37)-N6)-dimethylallyltransferase MiaA	NA	NA	NA	NA
WP_012656803.1\|990709_991183_-	glutathione peroxidase	Q70H87	Fowlpox_virus	7.6e-25	40.1
WP_012656804.1\|991241_992519_+	GTPase HflX	NA	NA	NA	NA
WP_012656805.1\|992523_993783_+	methionine gamma-lyase family protein	NA	NA	NA	NA
WP_041635912.1\|993869_994223_+	MerR family transcriptional regulator	NA	NA	NA	NA
WP_012656807.1\|994239_995577_+	type I glutamate--ammonia ligase	NA	NA	NA	NA
WP_012656808.1\|995685_996810_-\|integrase	site-specific integrase	A8ATM2	Listeria_phage	4.0e-24	28.8
WP_012656809.1\|996936_997887_-	Abi family protein	NA	NA	NA	NA
997810:997826	attL	NA	NA	NA	NA
WP_041635913.1\|997988_998372_-	hypothetical protein	NA	NA	NA	NA
WP_041635914.1\|998450_999476_-	SAP domain-containing protein	NA	NA	NA	NA
WP_012656812.1\|999505_999991_-	hypothetical protein	A0A2H4JD66	uncultured_Caudovirales_phage	3.5e-49	55.9
WP_012656813.1\|1000003_1000339_-	helix-turn-helix transcriptional regulator	A0A223LGP9	Staphylococcus_phage	4.9e-26	59.8
WP_041635915.1\|1000520_1000760_+	helix-turn-helix transcriptional regulator	A0A2H4J9X2	uncultured_Caudovirales_phage	2.2e-28	77.6
WP_012656814.1\|1000775_1001495_+	phage antirepressor KilAC domain-containing protein	Q8SDM9	Staphylococcus_phage	7.6e-85	63.3
WP_041635917.1\|1001874_1002063_+	helix-turn-helix transcriptional regulator	A0A0H4IP57	Staphylococcus_phage	4.1e-14	68.3
WP_041635918.1\|1002059_1002275_+	hypothetical protein	NA	NA	NA	NA
WP_041635919.1\|1002271_1002535_-	CRISPR-associated endonuclease Cas2	A0A0N9STP5	Staphylococcus_phage	2.9e-26	65.5
WP_050742472.1\|1002674_1002866_+	hypothetical protein	NA	NA	NA	NA
WP_158298070.1\|1002862_1003039_+	hypothetical protein	NA	NA	NA	NA
WP_157827427.1\|1003117_1003291_+	hypothetical protein	NA	NA	NA	NA
WP_148184259.1\|1003321_1003576_+	hypothetical protein	NA	NA	NA	NA
WP_158298071.1\|1003616_1003772_+	hypothetical protein	NA	NA	NA	NA
WP_012656815.1\|1003859_1004114_+	hypothetical protein	NA	NA	NA	NA
WP_041635923.1\|1004103_1004307_+	helix-turn-helix transcriptional regulator	A0A1W6JPB6	Staphylococcus_phage	9.8e-06	43.9
WP_012656817.1\|1005225_1006026_+	PD-(D/E)XK nuclease-like domain-containing protein	A0A290GJV0	Caldibacillus_phage	1.5e-65	51.9
WP_012656818.1\|1006044_1006371_+	hypothetical protein	NA	NA	NA	NA
WP_012656819.1\|1006363_1006822_+	single-stranded DNA-binding protein	A0A1Q1PW11	Staphylococcus_phage	1.5e-41	56.1
WP_012656820.1\|1006850_1007741_+	DnaD domain protein	A0A1Q1PVU4	Staphylococcus_phage	2.2e-57	55.4
WP_041635924.1\|1007741_1007987_+	hypothetical protein	NA	NA	NA	NA
WP_012656821.1\|1007998_1008364_+	hypothetical protein	B5SP14	Lactococcus_phage	3.5e-09	32.4
WP_157820996.1\|1008360_1008531_+	hypothetical protein	NA	NA	NA	NA
WP_041635925.1\|1008534_1009062_+	dUTP diphosphatase	NA	NA	NA	NA
WP_157821483.1\|1009158_1009317_+	hypothetical protein	NA	NA	NA	NA
WP_012656823.1\|1009303_1009729_+	RusA family crossover junction endodeoxyribonuclease	A0A1D6Z252	Staphylococcus_phage	3.5e-37	56.5
WP_070105570.1\|1010356_1010677_+	DUF3310 domain-containing protein	A0A1D6Z251	Staphylococcus_phage	5.2e-17	52.4
WP_012656825.1\|1010745_1011306_+	hypothetical protein	A0A2H4J6J3	uncultured_Caudovirales_phage	5.3e-09	30.5
WP_012656826.1\|1011451_1011718_+	hypothetical protein	NA	NA	NA	NA
WP_041635927.1\|1012080_1012560_+\|terminase	terminase small subunit	A0A0N9BAX3	Staphylococcus_phage	1.5e-23	43.3
WP_012656828.1\|1012552_1013803_+\|terminase	PBSX family phage terminase large subunit	A0A0H3U2R6	Staphylococcus_phage	9.2e-195	79.9
WP_148184261.1\|1013812_1015252_+\|portal	phage portal protein	Q4ZE36	Staphylococcus_virus	1.1e-154	59.6
WP_050742428.1\|1015232_1017017_+\|capsid	minor capsid protein	Q4ZE35	Staphylococcus_virus	3.9e-61	41.9
WP_041635928.1\|1017077_1017431_+	hypothetical protein	NA	NA	NA	NA
WP_041635929.1\|1017580_1018180_+	DUF4355 domain-containing protein	H9A0N2	Staphylococcus_phage	1.3e-05	33.3
WP_012656833.1\|1018195_1019107_+	hypothetical protein	Q4ZE33	Staphylococcus_virus	4.8e-124	75.7
WP_041635931.1\|1019152_1019419_+	hypothetical protein	NA	NA	NA	NA
WP_012656834.1\|1019402_1019726_+\|head,tail	phage head-tail connector protein	A0A1W6JNR3	Staphylococcus_phage	2.3e-17	45.9
WP_041635933.1\|1019725_1020028_+	hypothetical protein	NA	NA	NA	NA
WP_012656835.1\|1020021_1020366_+	HK97 gp10 family phage protein	I1W643	Staphylococcus_phage	1.9e-09	36.9
WP_012656836.1\|1020370_1020754_+	DUF3168 domain-containing protein	B7T0D6	Staphylococcus_virus	1.1e-08	28.2
WP_012656837.1\|1020765_1021320_+\|tail	phage major tail protein, TP901-1 family	A0A2P1JTU8	Anoxybacillus_phage	8.1e-26	39.9
WP_012656838.1\|1021385_1021763_+\|tail	tail assembly chaperone	A0A1J0MFH0	Staphylococcus_phage	9.4e-26	50.4
WP_012656839.1\|1021780_1022128_+	hypothetical protein	NA	NA	NA	NA
WP_012656840.1\|1022142_1025400_+	hypothetical protein	Q4ZC60	Staphylococcus_virus	5.0e-91	40.0
WP_148184263.1\|1025503_1026688_+	hypothetical protein	A0A0B5CU25	Listeria_phage	1.9e-16	32.4
WP_041635935.1\|1026730_1027543_+\|tail	phage tail family protein	NA	NA	NA	NA
WP_012656841.1\|1027539_1029714_+\|tail	phage tail protein	A0A1Q1PW30	Staphylococcus_phage	4.6e-32	43.3
WP_193330447.1\|1029661_1030345_+	hypothetical protein	Q4ZD63	Staphylococcus_phage	2.8e-44	74.5
WP_158298072.1\|1030337_1030505_+	hypothetical protein	NA	NA	NA	NA
WP_041635936.1\|1030550_1030826_+	hypothetical protein	Q4ZD61	Staphylococcus_phage	1.8e-26	65.1
WP_012656843.1\|1030839_1031352_+\|holin	phage holin family protein	H9A0W5	Staphylococcus_phage	3.5e-39	53.6
WP_050742430.1\|1031407_1032268_+	N-acetylmuramoyl-L-alanine amidase	M1PRV7	Streptococcus_phage	9.2e-45	38.1
WP_012656845.1\|1032925_1034080_-\|integrase	tyrosine-type recombinase/integrase	A0A2H4JCB7	uncultured_Caudovirales_phage	3.9e-22	25.6
WP_012656846.1\|1034084_1034546_-	ImmA/IrrE family metallo-endopeptidase	NA	NA	NA	NA
WP_148184264.1\|1034668_1034893_+	hypothetical protein	A0A0K1LLB1	Staphylococcus_phage	1.3e-06	46.9
WP_083754297.1\|1034883_1035198_-	hypothetical protein	A0A0K1LKD8	Staphylococcus_phage	9.5e-32	63.0
WP_012656848.1\|1035809_1036889_-	DUF4352 domain-containing protein	NA	NA	NA	NA
WP_012656849.1\|1036901_1037975_-	type I restriction enzyme HsdR N-terminal domain-containing protein	A0A1S5SAB0	Streptococcus_phage	7.6e-89	46.2
WP_041635938.1\|1038496_1038748_+	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_012656850.1\|1038863_1039367_+	hypothetical protein	A0A290FZK9	Caldibacillus_phage	3.1e-08	26.9
WP_050742431.1\|1039377_1039938_+	helix-turn-helix transcriptional regulator	H9A0L8	Staphylococcus_phage	1.8e-12	63.9
WP_041635940.1\|1039938_1040184_+	hypothetical protein	NA	NA	NA	NA
WP_041635941.1\|1040185_1040377_+	hypothetical protein	NA	NA	NA	NA
WP_041635943.1\|1040470_1040707_-	hypothetical protein	NA	NA	NA	NA
WP_041635944.1\|1040845_1041607_+	phage antirepressor KilAC domain-containing protein	A0A2H4JCT2	uncultured_Caudovirales_phage	1.3e-103	77.1
WP_041635945.1\|1041603_1041795_+	hypothetical protein	NA	NA	NA	NA
WP_012656853.1\|1041996_1042938_+	YqaJ viral recombinase family protein	A0A2H4JA52	uncultured_Caudovirales_phage	8.5e-76	46.2
WP_012656854.1\|1042943_1043774_+	recombination protein RecT	S6AVW6	Thermus_phage	5.3e-90	64.5
WP_012656855.1\|1043805_1044396_+	phage replisome organizer N-terminal domain-containing protein	A0A1S5SAV1	Streptococcus_phage	8.3e-29	52.5
WP_041635947.1\|1044367_1044697_+	DnaD domain protein	A0A0P0HRQ2	Lactobacillus_phage	2.6e-08	41.8
WP_041635949.1\|1044674_1045460_+	ATP-binding protein	A0A2I6PDA0	Staphylococcus_phage	6.1e-35	35.8
1044940:1044956	attR	NA	NA	NA	NA
WP_041635950.1\|1045485_1045809_+	hypothetical protein	NA	NA	NA	NA
WP_158298073.1\|1045801_1045978_+	hypothetical protein	NA	NA	NA	NA
WP_158298074.1\|1045949_1046126_+	hypothetical protein	NA	NA	NA	NA
WP_012656859.1\|1046122_1046632_+	single-stranded DNA-binding protein	A0A1W6JPL9	Staphylococcus_phage	6.2e-49	58.6
WP_041635952.1\|1046658_1046937_+	hypothetical protein	NA	NA	NA	NA
WP_041635954.1\|1046933_1047113_+	hypothetical protein	NA	NA	NA	NA
WP_041635956.1\|1047362_1047596_+	phage protein	A0A2H4JCC5	uncultured_Caudovirales_phage	1.5e-13	54.8
WP_012656860.1\|1047598_1048111_+	HNH endonuclease	NA	NA	NA	NA
WP_041635957.1\|1048122_1048629_+	hypothetical protein	NA	NA	NA	NA
WP_157820998.1\|1048641_1048815_+	hypothetical protein	NA	NA	NA	NA
WP_041635959.1\|1048817_1049039_+	hypothetical protein	NA	NA	NA	NA
WP_041635960.1\|1049051_1049294_+	hypothetical protein	NA	NA	NA	NA
WP_041635961.1\|1049321_1049513_+	hypothetical protein	NA	NA	NA	NA
WP_041635962.1\|1049514_1049739_+	hypothetical protein	NA	NA	NA	NA
WP_041635963.1\|1049769_1049994_+	hypothetical protein	NA	NA	NA	NA
WP_041635965.1\|1050062_1050257_+	hypothetical protein	A0A076G540	Staphylococcus_phage	6.1e-13	52.5
WP_041635966.1\|1050278_1050497_+	hypothetical protein	NA	NA	NA	NA
WP_041635967.1\|1050518_1050698_+	hypothetical protein	NA	NA	NA	NA
WP_158298075.1\|1050718_1050889_+	hypothetical protein	NA	NA	NA	NA
WP_041635968.1\|1051010_1051373_+	hypothetical protein	NA	NA	NA	NA
WP_157820996.1\|1051369_1051540_+	hypothetical protein	NA	NA	NA	NA
WP_148184302.1\|1051552_1051846_+	hypothetical protein	A0A142F1R8	Bacillus_phage	4.0e-32	68.4
WP_157821164.1\|1051860_1052034_+	hypothetical protein	NA	NA	NA	NA
WP_012656864.1\|1052548_1052953_+	hypothetical protein	A0A290FZR5	Caldibacillus_phage	1.7e-12	36.4
WP_012656865.1\|1053019_1053892_+	hypothetical protein	NA	NA	NA	NA
WP_041635969.1\|1054172_1054376_+	hypothetical protein	NA	NA	NA	NA
WP_012656866.1\|1054488_1055202_+	hypothetical protein	A0A2P1JTW4	Anoxybacillus_phage	5.2e-25	36.6
WP_012656867.1\|1055198_1056491_+\|terminase	PBSX family phage terminase large subunit	A0A2P1JTW5	Anoxybacillus_phage	3.7e-130	58.7
WP_012656868.1\|1056503_1058123_+	hypothetical protein	A0A1U9WQP5	Geobacillus_phage	1.9e-131	46.8
WP_012656869.1\|1058127_1059216_+	hypothetical protein	A0A2H4J2F6	uncultured_Caudovirales_phage	5.2e-69	42.5
WP_050742432.1\|1059190_1059502_+	ImmA/IrrE family metallo-endopeptidase	NA	NA	NA	NA
WP_167313621.1\|1059518_1059668_-	hypothetical protein	NA	NA	NA	NA
WP_012656871.1\|1060006_1060612_+	phage scaffolding protein	L0P7B0	Lactobacillus_phage	1.4e-15	28.7
WP_012656872.1\|1060625_1061000_+	hypothetical protein	NA	NA	NA	NA
WP_012656873.1\|1061026_1062031_+\|capsid	major capsid protein	A0A2H4J2G1	uncultured_Caudovirales_phage	1.4e-68	43.2
WP_041635970.1\|1062072_1062348_+	hypothetical protein	NA	NA	NA	NA
WP_012656874.1\|1062365_1062749_+	hypothetical protein	NA	NA	NA	NA
WP_012656875.1\|1062748_1063093_+	hypothetical protein	A0A218KCG8	Bacillus_phage	4.5e-11	39.1
WP_041635971.1\|1063082_1063565_+	HK97 gp10 family phage protein	A0A1U9WQQ7	Geobacillus_phage	4.5e-33	48.1
WP_012656877.1\|1063569_1063950_+	hypothetical protein	A0A2H4JAC9	uncultured_Caudovirales_phage	8.0e-17	40.7
WP_012656878.1\|1064013_1064592_+	hypothetical protein	M4ZS18	Bacillus_phage	1.2e-32	39.4
WP_012656879.1\|1064667_1065189_+	hypothetical protein	A0A218KCI2	Bacillus_phage	2.5e-08	33.8

DBSCAN-SWA_5

1071402 : 1081914

Staphylococcus_phage(85.71%)

tail,holin

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_012656883.1\|1071402_1071837_+	hypothetical protein	A0A286QMT6	Streptococcus_phage	7.3e-06	30.5
WP_012656884.1\|1071836_1075232_+\|tail	phage tail protein	A0A1Q1PW30	Staphylococcus_phage	4.7e-76	32.8
WP_158298076.1\|1075224_1075392_+	hypothetical protein	NA	NA	NA	NA
WP_041635973.1\|1075436_1075715_+	hypothetical protein	Q4ZD61	Staphylococcus_phage	1.3e-24	65.9
WP_012656885.1\|1075728_1076241_+\|holin	phage holin family protein	H9A0W5	Staphylococcus_phage	2.0e-39	54.3
WP_012656886.1\|1076346_1077309_+	family 20 glycosylhydrolase	NA	NA	NA	NA
WP_050742433.1\|1077385_1077652_+\|holin	phage holin	A0A1D6Z272	Staphylococcus_phage	1.2e-06	43.1
WP_012656887.1\|1077654_1078560_+	N-acetylmuramoyl-L-alanine amidase	A0A1W6JQL2	Staphylococcus_phage	3.1e-75	62.4
WP_012656888.1\|1078894_1080259_+	AAA family ATPase	NA	NA	NA	NA
WP_012656889.1\|1080251_1080857_+	hypothetical protein	NA	NA	NA	NA
WP_148184265.1\|1081476_1081914_-	YolD-like family protein	A0A1Q1PW34	Staphylococcus_phage	1.6e-16	39.8

DBSCAN-SWA_6

1370303 : 1388278

uncultured_Mediterranean_phage(27.27%)

tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_012657172.1\|1370303_1372082_-\|tRNA	aspartate--tRNA ligase	A0A2K9L0E9	Tupanvirus	1.1e-15	28.1
WP_012657173.1\|1372085_1373348_-\|tRNA	histidine--tRNA ligase	A0A2I2L577	Orpheovirus	3.4e-19	25.4
WP_012657174.1\|1373647_1374493_-	N-acetylmuramoyl-L-alanine amidase	A0A0N9SGH1	Paenibacillus_phage	5.2e-16	34.5
WP_012657175.1\|1374489_1374942_-\|tRNA	D-tyrosyl-tRNA(Tyr) deacylase	NA	NA	NA	NA
WP_012657176.1\|1374950_1377143_-	bifunctional (p)ppGpp synthetase/guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase	A0A2I2L310	Orpheovirus	2.4e-12	39.7
WP_012657177.1\|1377247_1377769_-	adenine phosphoribosyltransferase	A0A1V0SKE5	Klosneuvirus	9.6e-29	43.1
WP_041636043.1\|1377779_1380047_-	single-stranded-DNA-specific exonuclease RecJ	A7KV88	Bacillus_phage	4.9e-69	30.1
WP_041636044.1\|1380068_1381184_-	amidohydrolase	NA	NA	NA	NA
WP_012657180.1\|1381176_1382292_-	dipeptide epimerase	Q6A202	Oenococcus_phage	3.5e-12	25.3
WP_012657181.1\|1382443_1384735_-	protein translocase subunit SecDF	A0A1B1IVP7	uncultured_Mediterranean_phage	4.2e-28	31.4
WP_041636045.1\|1384798_1385077_-	preprotein translocase subunit YajC	A0A1B1IVR5	uncultured_Mediterranean_phage	3.8e-08	37.5
WP_012657182.1\|1385088_1386228_-\|tRNA	tRNA guanosine(34) transglycosylase Tgt	A0A1B1IVQ4	uncultured_Mediterranean_phage	1.9e-85	44.1
WP_012657183.1\|1386239_1387262_-\|tRNA	tRNA preQ1(34) S-adenosylmethionine ribosyltransferase-isomerase QueA	NA	NA	NA	NA
WP_012657184.1\|1387264_1388278_-	Holliday junction branch migration DNA helicase RuvB	A0A127AWE7	Bacillus_phage	6.2e-08	25.3

DBSCAN-SWA_7

1567039 : 1575114

Staphylococcus_phage(62.5%)

transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_012657352.1\|1567039_1567771_+\|transposase	IS3 family transposase	A0A2I6AZV9	Macacine_betaherpesvirus	7.6e-40	47.3
WP_012657353.1\|1567817_1568555_-	nicotinamide mononucleotide transporter	U5J9C5	Bacillus_phage	5.0e-31	37.4
WP_012657354.1\|1568565_1569660_-	AAA family ATPase	A0A2K9VDE3	Lactobacillus_phage	1.7e-67	37.4
WP_041636092.1\|1569954_1570512_-	energy-coupled thiamine transporter ThiT	NA	NA	NA	NA
WP_012657356.1\|1570780_1571773_+	proline dehydrogenase family protein	A0A2H4PQT6	Staphylococcus_phage	8.3e-106	59.5
WP_012657357.1\|1571809_1572274_-	6,7-dimethyl-8-ribityllumazine synthase	A0A2H4PQS3	Staphylococcus_phage	1.4e-42	69.3
WP_012657358.1\|1572270_1573461_-	bifunctional 3,4-dihydroxy-2-butanone-4-phosphate synthase/GTP cyclohydrolase II	A0A2H4PQS2	Staphylococcus_phage	2.4e-128	58.1
WP_012657359.1\|1573460_1574084_-	riboflavin synthase	A0A2H4PQS5	Staphylococcus_phage	5.3e-42	44.4
WP_012657360.1\|1574088_1575114_-	bifunctional diaminohydroxyphosphoribosylaminopyrimidine deaminase/5-amino-6-(5-phosphoribosylamino)uracil reductase RibD	A0A2H4PQS8	Staphylococcus_phage	2.4e-60	38.6

DBSCAN-SWA_8

1614773 : 1629860

Staphylococcus_phage(80.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_012657398.1\|1614773_1618304_-	S8 family serine peptidase	A0A217EQY2	Bacillus_phage	5.5e-19	35.9
WP_041636108.1\|1618398_1618593_-	hypothetical protein	NA	NA	NA	NA
WP_012657399.1\|1618697_1619408_-	transaldolase	E3SKN5	Synechococcus_phage	4.2e-19	35.1
WP_041636109.1\|1619542_1619839_+	hypothetical protein	NA	NA	NA	NA
WP_012657400.1\|1619877_1620213_+	CrcB family protein	A0A2H4PQR0	Staphylococcus_phage	3.9e-07	42.1
WP_012657401.1\|1620209_1620542_+	CrcB family protein	NA	NA	NA	NA
WP_041636110.1\|1620686_1621601_-	NERD domain-containing protein	A0A2H4PQQ8	Staphylococcus_phage	7.3e-56	44.8
WP_157819830.1\|1621818_1621989_+	hypothetical protein	NA	NA	NA	NA
WP_012657403.1\|1622030_1623221_-	methionine adenosyltransferase	A0A2H4PQS6	Staphylococcus_phage	3.7e-169	78.6
WP_041636111.1\|1623608_1625201_+	phosphoenolpyruvate carboxykinase (ATP)	A0A2H4PQN1	Staphylococcus_phage	2.7e-215	70.0
WP_050742445.1\|1625250_1626009_-	prolyl oligopeptidase family serine peptidase	A0A2H4PQM6	Staphylococcus_phage	3.3e-54	49.2
WP_012657406.1\|1625986_1626466_-	nucleoside triphosphatase YtkD	NA	NA	NA	NA
WP_041636113.1\|1626503_1627262_+	hypothetical protein	NA	NA	NA	NA
WP_041636114.1\|1627271_1627496_+	membrane protein insertion efficiency factor YidD	A0A2H4PQM5	Staphylococcus_phage	1.8e-24	65.8
WP_012657408.1\|1627531_1628494_-	hypothetical protein	A0A2H4PQM0	Staphylococcus_phage	3.6e-37	34.7
WP_041636116.1\|1628477_1629860_-	o-succinylbenzoate--CoA ligase	A0A2H4PQM9	Staphylococcus_phage	7.5e-89	41.3

DBSCAN-SWA_9

1637652 : 1670491

Staphylococcus_phage(65.38%)

portal,capsid,integrase,tail,terminase,head,protease,holin

attL 1636724:1636783|attR 1670746:1670825

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
1636724:1636783	attL	NA	NA	NA	NA
WP_070105564.1\|1637652_1638429_-	CHAP domain-containing protein	Q4ZC44	Staphylococcus_virus	1.2e-48	57.8
WP_012657417.1\|1638468_1638771_-\|holin	phage holin	A0A0H3UYV6	Geobacillus_virus	5.6e-13	44.9
WP_041636120.1\|1638790_1639231_-	hypothetical protein	NA	NA	NA	NA
WP_041636121.1\|1639293_1639581_-	hypothetical protein	Q4ZD61	Staphylococcus_phage	2.1e-25	61.8
WP_158298082.1\|1639626_1639794_-	hypothetical protein	NA	NA	NA	NA
WP_012657419.1\|1639786_1644463_-	hypothetical protein	A0A1Q1PVY1	Staphylococcus_phage	8.6e-254	37.3
WP_083754283.1\|1644478_1645561_-\|tail	phage tail family protein	A0A1Q1PVY2	Staphylococcus_phage	2.4e-122	59.4
WP_050742447.1\|1645567_1645999_-\|tail	phage tail family protein	A0A2H4J1X6	uncultured_Caudovirales_phage	5.0e-39	51.0
WP_012657422.1\|1646008_1650370_-	peptidoglycan DD-metalloendopeptidase family protein	A0A2H4J669	uncultured_Caudovirales_phage	3.6e-84	36.9
WP_158298083.1\|1650394_1650544_-	hypothetical protein	NA	NA	NA	NA
WP_012657423.1\|1650603_1650957_-	hypothetical protein	NA	NA	NA	NA
WP_012657424.1\|1651027_1651615_-	hypothetical protein	NA	NA	NA	NA
WP_012657425.1\|1651627_1652017_-	hypothetical protein	NA	NA	NA	NA
WP_012657426.1\|1652013_1652406_-	HK97 gp10 family phage protein	D2JLF2	Staphylococcus_phage	2.8e-09	33.3
WP_012657427.1\|1652402_1652726_-\|head,tail	head-tail adaptor protein	NA	NA	NA	NA
WP_012657428.1\|1652694_1653039_-\|head,tail	phage gp6-like head-tail connector protein	A0A0D4DBY0	Staphylococcus_phage	8.9e-07	33.7
WP_041636124.1\|1653010_1653217_-	hypothetical protein	NA	NA	NA	NA
WP_012657429.1\|1653231_1654365_-\|capsid	phage major capsid protein	A0A2H4J7D0	uncultured_Caudovirales_phage	1.0e-35	34.7
WP_041636125.1\|1654374_1654944_-\|head,protease	HK97 family phage prohead protease	D2JLE7	Staphylococcus_phage	2.3e-44	48.8
WP_012657431.1\|1654927_1656169_-\|portal	phage portal protein	A0A0D4DC70	Staphylococcus_phage	2.2e-47	32.6
WP_157827310.1\|1656172_1656346_-	hypothetical protein	NA	NA	NA	NA
WP_012657432.1\|1656342_1658049_-\|terminase	terminase	D2JLE4	Staphylococcus_phage	1.8e-156	51.2
WP_012657433.1\|1658045_1658531_-\|terminase	phage terminase small subunit P27 family	D7PQ38	Enterococcus_phage	5.8e-12	35.5
WP_041636483.1\|1658662_1659010_-	HNH endonuclease	A0A2H4J3B4	uncultured_Caudovirales_phage	6.4e-21	47.7
WP_012657435.1\|1659198_1659615_-	hypothetical protein	A0A1D6Z235	Staphylococcus_phage	4.6e-18	37.2
WP_157820257.1\|1659847_1660021_-	hypothetical protein	NA	NA	NA	NA
WP_041636127.1\|1660101_1660302_-	hypothetical protein	NA	NA	NA	NA
WP_012657436.1\|1660294_1660657_-	hypothetical protein	NA	NA	NA	NA
WP_012657437.1\|1660649_1661084_-	hypothetical protein	NA	NA	NA	NA
WP_041636128.1\|1661080_1661266_-	hypothetical protein	NA	NA	NA	NA
WP_012657438.1\|1661262_1661571_-	hypothetical protein	NA	NA	NA	NA
WP_148184307.1\|1661721_1662069_-	hypothetical protein	Q4ZD40	Staphylococcus_phage	1.0e-18	61.4
WP_158298084.1\|1662098_1662251_-	hypothetical protein	NA	NA	NA	NA
WP_041636130.1\|1662261_1662774_-	Holliday junction resolvase RecU	R9TMF8	Paenibacillus_phage	2.0e-15	34.8
WP_041636131.1\|1662894_1663083_-	hypothetical protein	NA	NA	NA	NA
WP_041636132.1\|1663096_1663345_-	hypothetical protein	NA	NA	NA	NA
WP_041636134.1\|1663367_1663850_-	single-stranded DNA-binding protein	H9A0L6	Staphylococcus_phage	7.2e-55	71.0
WP_012657441.1\|1663839_1664172_-	hypothetical protein	NA	NA	NA	NA
WP_041636135.1\|1664507_1664810_-	hypothetical protein	NA	NA	NA	NA
WP_012657443.1\|1664802_1665759_-	DnaD domain protein	A0A1J0MGB2	Staphylococcus_phage	1.2e-32	60.6
WP_041636137.1\|1665795_1666056_-	hypothetical protein	NA	NA	NA	NA
WP_041636138.1\|1666045_1666804_-	phage antirepressor KilAC domain-containing protein	Q8SDM9	Staphylococcus_phage	1.7e-95	71.5
WP_041636139.1\|1666893_1667082_-	hypothetical protein	NA	NA	NA	NA
WP_012657445.1\|1667078_1667387_-	DUF771 domain-containing protein	A0A1W6JPI1	Staphylococcus_phage	6.7e-06	36.5
WP_041636140.1\|1667409_1667631_-	helix-turn-helix transcriptional regulator	A0A1J0MFH4	Staphylococcus_phage	2.9e-19	62.3
WP_012657446.1\|1667768_1668398_+	helix-turn-helix domain-containing protein	A0A1J0MG99	Staphylococcus_phage	2.6e-73	64.6
WP_041636142.1\|1668469_1669321_+	HIRAN domain-containing protein	A0A1X9H037	Staphylococcus_phage	3.3e-10	23.8
WP_012657448.1\|1669432_1670491_+\|integrase	site-specific integrase	A0A2H4JGN1	uncultured_Caudovirales_phage	2.7e-86	44.9
1670746:1670825	attR	NA	NA	NA	NA

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. NC_011996

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection

2. NC_011999

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection