CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NC_012891	Streptococcus dysgalactiae subsp. equisimilis GGS_124 chromosome 1, complete sequence	4 crisprs	DEDDh,DinG,csm6,csa3,csn2,cas2,cas1,cas9,cas3	2	18	7	2

Results visualization

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CRISPR-Cas detection and classification

Crispr_ID: NC_012891_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_012891_1

828821-828928

Orphan

Consensus_repeat	Method
AGACGAGGAGCCTGCTCAAGAGGA	CRISPRCasFinder

1 spacers

The CRISPR arrays of NC_012891_1

>merge|NC_012891|1|828821-828928|CRISPRCasFinder
AGACGAGGAGCCTGCTCAAGAGGACGCCTTAAATCCAACACCTGAAGGCCAACCAACGCCTGAAGTTGACGAAGTACTGGCAGCAGACGAGGAACCTGCTCAAGAGGA

>NC_012891|1|1|828821-828928|CRISPRCasFinder
AGACGAGGAGCCTGCTCAAGAGGA	CGCCTTAAATCCAACACCTGAAGGCCAACCAACGCCTGAAGTTGACGAAGTACTGGCAGC
AGACGAGGAACCTGCTCAAGAGGA

Protein	Signature genes	Signature genes Name	Protein_function
NC_012891.1\|WP_171841606.1\|833691_834714_-\|IS30-family-transposase	unknown	unknown	gnl\|CDD\|225382
NC_012891.1\|WP_012766851.1\|838601_839345_+\|hypothetical-protein	unknown	unknown	unknown
NC_012891.1\|WP_041788944.1\|811797_813030_+\|HAMP-domain-containing-histidine-kinase	unknown	unknown	gnl\|CDD\|223715
NC_012891.1\|WP_003054200.1\|836335_836506_+\|hypothetical-protein	unknown	unknown	unknown
NC_012891.1\|WP_041788957.1\|824059_825379_+\|fibrinogen-binding-adhesin-SdrG-C-terminal-domain-containing-protein	unknown	unknown	gnl\|CDD\|380076
NC_012891.1\|WP_002984985.1\|811120_811789_+\|response-regulator-transcription-factor	unknown	unknown	gnl\|CDD\|223816
NC_012891.1\|WP_012766841.1\|818286_819165_+\|mevalonate-kinase	unknown	unknown	gnl\|CDD\|224493
NC_012891.1\|WP_041788951.1\|814616_816338_+\|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|224055
NC_012891.1\|WP_003062183.1\|832322_833504_-\|hydroxymethylglutaryl-CoA-synthase	unknown	unknown	gnl\|CDD\|213655
NC_012891.1\|WP_003062424.1\|819146_820091_+\|diphosphomevalonate-decarboxylase	unknown	unknown	gnl\|CDD\|130307
NC_012891.1\|WP_003054192.1\|836619_837849_+\|ATP-dependent-Clp-protease-ATP-binding-subunit-ClpX	unknown	unknown	gnl\|CDD\|235422
NC_012891.1\|WP_041788963.1\|829359_830877_-\|helix-turn-helix-domain-containing-protein	unknown	unknown	gnl\|CDD\|285470
NC_012891.1\|WP_012766848.1\|831064_832342_-\|hydroxymethylglutaryl-CoA-reductase,-degradative	unknown	unknown	gnl\|CDD\|153082
NC_012891.1\|WP_012766843.1\|821083_822076_+\|type-2-isopentenyl-diphosphate-Delta-isomerase	unknown	unknown	gnl\|CDD\|235465
NC_012891.1\|WP_003054187.1\|835818_836316_+\|dihydrofolate-reductase	unknown	unknown	gnl\|CDD\|365932
NC_012891.1\|WP_171841606.1\|825454_826477_+\|IS30-family-transposase	unknown	unknown	gnl\|CDD\|225382
NC_012891.1\|WP_003054196.1\|834898_835738_+\|thymidylate-synthase	unknown	unknown	gnl\|CDD\|234984
NC_012891.1\|WP_041788954.1\|820083_821097_+\|phosphomevalonate-kinase	unknown	unknown	gnl\|CDD\|224493
NC_012891.1\|WP_012766840.1\|816339_818082_+\|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|224055
NC_012891.1\|WP_012766850.1\|837858_838458_+\|YihA-family-ribosome-biogenesis-GTP-binding-protein	unknown	unknown	gnl\|CDD\|234770

Protein	Function_ID	Function_description	E-value
NC_012891.1\|WP_171841606.1\|833691_834714_-\|IS30-family-transposase	gnl\|CDD\|225382	COG2826, Tra8, Transposase and inactivated derivatives, IS30 family [DNA replication, recombination, and repair].	2.27304e-75
NC_012891.1\|WP_041788944.1\|811797_813030_+\|HAMP-domain-containing-histidine-kinase	gnl\|CDD\|223715	COG0642, BaeS, Signal transduction histidine kinase [Signal transduction mechanisms].	1.3541e-26
NC_012891.1\|WP_041788957.1\|824059_825379_+\|fibrinogen-binding-adhesin-SdrG-C-terminal-domain-containing-protein	gnl\|CDD\|380076	pfam17961, Big_8, Bacterial Ig domain. This entry represents a bacterial Ig-fold domain that is found in a wide range of bacterial cell surface adherence proteins.	9.089e-24
NC_012891.1\|WP_002984985.1\|811120_811789_+\|response-regulator-transcription-factor	gnl\|CDD\|223816	COG0745, OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription].	9.08126e-68
NC_012891.1\|WP_012766841.1\|818286_819165_+\|mevalonate-kinase	gnl\|CDD\|224493	COG1577, ERG12, Mevalonate kinase [Lipid metabolism].	1.4249e-102
NC_012891.1\|WP_041788951.1\|814616_816338_+\|ABC-transporter-ATP-binding-protein	gnl\|CDD\|224055	COG1132, MdlB, ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms].	8.38874e-136
NC_012891.1\|WP_003062183.1\|832322_833504_-\|hydroxymethylglutaryl-CoA-synthase	gnl\|CDD\|213655	TIGR01835, 3-hydroxy-3-methylglutaryl_CoA_synthase, 3-hydroxy-3-methylglutaryl CoA synthase, prokaryotic clade. This clade of hydroxymethylglutaryl-CoA (HMG-CoA) synthases is found in a limited spectrum of mostly gram-positive bacteria which make isopentenyl pyrophosphate (IPP) via the mevalonate pathway. This pathway is found primarily in eukaryotes and archaea, but the bacterial homologs are distinct, having aparrently diverged after being laterally transferred from an early eukaryote. HMG-CoA synthase is the first step in the pathway and joins acetyl-CoA with acetoacetyl-CoA with the release of one molecule of CoA. The Borellia sequence may have resulted from a separate lateral transfer event.	0
NC_012891.1\|WP_003062424.1\|819146_820091_+\|diphosphomevalonate-decarboxylase	gnl\|CDD\|130307	TIGR01240, Diphosphomevalonate_decarboxylase, diphosphomevalonate decarboxylase. This enzyme catalyzes the last step in the synthesis of isopentenyl diphosphate (IPP) in the mevalonate pathway. Alternate names: mevalonate diphosphate decarboxylase; pyrophosphomevalonate decarboxylase [Central intermediary metabolism, Other].	1.42438e-153
NC_012891.1\|WP_003054192.1\|836619_837849_+\|ATP-dependent-Clp-protease-ATP-binding-subunit-ClpX	gnl\|CDD\|235422	PRK05342, clpX, ATP-dependent Clp protease ATP-binding subunit ClpX.	0
NC_012891.1\|WP_041788963.1\|829359_830877_-\|helix-turn-helix-domain-containing-protein	gnl\|CDD\|285470	pfam08270, PRD_Mga, M protein trans-acting positive regulator (MGA) PRD domain. Mga is a DNA-binding protein that activates the expression of several important virulence genes in group A streptococcus in response to changing environmental conditions. This corresponds to the PRD like region.	1.1806e-09
NC_012891.1\|WP_012766848.1\|831064_832342_-\|hydroxymethylglutaryl-CoA-reductase,-degradative	gnl\|CDD\|153082	cd00644, HMG-CoA_reductase_classII, Class II hydroxymethylglutaryl-coenzyme A (HMG-CoA) reductase (HMGR). Hydroxymethylglutaryl-coenzyme A (HMG-CoA) reductase (HMGR), class II, prokaryotic enzyme is a homodimer. Class II enzymes are found primarily in prokaryotes and Archaeoglobus fulgidus and are soluble as they lack the membrane region. Enzymes catalyze the synthesis of coenzyme A and mevalonate in isoprenoid synthesis. Bacteria, such as Pseudomonas mevalonii, which rely solely on mevalonate for their carbon source, catalyze the reverse reaction, using an NAD-dependent HMGR to deacetylate mevalonate into 3-hydroxy-3-methylglutaryl-CoA. Human and bacterial HMGR differ in their active site architecture.	0
NC_012891.1\|WP_012766843.1\|821083_822076_+\|type-2-isopentenyl-diphosphate-Delta-isomerase	gnl\|CDD\|235465	PRK05437, PRK05437, isopentenyl pyrophosphate isomerase; Provisional.	2.05574e-162
NC_012891.1\|WP_003054187.1\|835818_836316_+\|dihydrofolate-reductase	gnl\|CDD\|365932	pfam00186, DHFR_1, Dihydrofolate reductase.	1.62651e-62
NC_012891.1\|WP_171841606.1\|825454_826477_+\|IS30-family-transposase	gnl\|CDD\|225382	COG2826, Tra8, Transposase and inactivated derivatives, IS30 family [DNA replication, recombination, and repair].	2.27304e-75
NC_012891.1\|WP_003054196.1\|834898_835738_+\|thymidylate-synthase	gnl\|CDD\|234984	PRK01827, thyA, thymidylate synthase; Reviewed.	9.16484e-116
NC_012891.1\|WP_041788954.1\|820083_821097_+\|phosphomevalonate-kinase	gnl\|CDD\|224493	COG1577, ERG12, Mevalonate kinase [Lipid metabolism].	1.50568e-81
NC_012891.1\|WP_012766840.1\|816339_818082_+\|ABC-transporter-ATP-binding-protein	gnl\|CDD\|224055	COG1132, MdlB, ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms].	9.62515e-152
NC_012891.1\|WP_012766850.1\|837858_838458_+\|YihA-family-ribosome-biogenesis-GTP-binding-protein	gnl\|CDD\|234770	PRK00454, engB, GTP-binding protein YsxC; Reviewed.	7.62008e-117

>NC_012891.1|WP_171841606.1|825454_826477_+|IS30-family-transposase
MSNINSTRKSSYSHLSATERGEIAAYLKMGKKPVEIARLLGRHRSTICREIKRGSVEQVKDKNGKQTFFNAYFADSGQRVYETNRQKSSYLKLNGCSARFIAQLESALTANIRLHSVDSFVQTYKVNHPEEVVPSTKTIYRYIKEGLLAIKPIDLPKMVSIRKRSKKVMKTNKKTLGKSIEERPEYINDRSEFGHWEIDLILGKKTKGEAVMLTLVERQTRYALGVKLEDKQSQTINRAVTHLISQYPIASITADNGSEFSLLSTLEAVDVYFAHPYSSHERGTNENFNGLLREYVPKGISLNPLTSEELDNYLTAINERPRRLLQYQSSTFLFELARTA
>NC_012891.1|WP_041788957.1|824059_825379_+|fibrinogen-binding-adhesin-SdrG-C-terminal-domain-containing-protein
MGTKNRKLKIEGETIVFKRERSRYSIRKNKCYGACSVFLGLTILTLAMAGGNVKAEEVGASNTPTSVEQPAAEVTENTSLVNTDNSSTETDQPASNSEEVTTLQPRAVAPANLVVENMEPKDVSDKIQVLDGKFLNVDQPIDPNQGENFDFETHFYVKDGVKSGDIFTIKLSDNISSFGDDSATIKNVEPLVDTTGDIIATGVANAKEKNITYTFTDAVSKKANVIGHIKFPLFIDRSKILENTTIPITVTVAGSSFTENISVNYTKAEELLSVITSVNKSGDIGQNVFETTYYVNNNKVNLSNPYIELFPINLQTKGPSSTDFSDLKNISIKLFRVPKNVELPSSFGVDTTQLEEVQNIDPRVIGDKIRIDLPKVSRDRYVMSVISPYKGNGENIEITGILYGGEQPSAVISSHILKEGTADASTEVPKGYFVEKPAL
>NC_012891.1|WP_012766843.1|821083_822076_+|type-2-isopentenyl-diphosphate-Delta-isomerase
MTNRKDDHIKYALKYQSPYNAFDDMELIHHSLPSYDVADINLSTHFAGQDFEFPFYINAMTGGSQKGKAVNEKLAKVAAATGIVMVTGSYSAALKNPNDASYRLHEVAEGLKLATNIGLDKPVERGQQTVKEMNPLFLQVHVNVMQELLMPEGERVFRTWKQHLADYASQIRVPIILKEVGFGMDVSTIKIAHELGIQTFDISGRGGTSFAYIENQRGLDRSYLNDWGQTTVQCLLNAQGLLDHVEILASGGVRHPLDMIKCLVLGARAVGLSRTVLELVEKYPVERVIDIVNGWKEDLKLIMCALDCRTIQDLRQVDYLLYGRLYQANH
>NC_012891.1|WP_041788954.1|820083_821097_+|phosphomevalonate-kinase
MLNYRVQTGGKLYLTGEYAILEPGQLALIQFIPLMITAEIGPSSHLQLASDMFDHKADMTPDASYGLIQATIKTFANYMGQSVEQLDPFSLSITGKLERDGKKFGIGSSGSVTLLTLKALSAYYQQPLSPELLFKLAAYTLLVQGDNGSMGDIACIAYQTLVAYTSFDRQQVSQWLSDMPLLDLLAKDWGYQIQVIEPALSCDFLVGWTKIPSISSQMIQQVKAKISPSFLTTSYELSQETIAALQSGDKEALKTSLTRASQLLRALDPVIYHPKLVTLVEACQWLDAVAKSSGSGGGDCGIALAFDRQAKETLINRWQAADIDLLYQERWGNHDES
>NC_012891.1|WP_003062424.1|819146_820091_+|diphosphomevalonate-decarboxylase
MDPNVITVTSYANIAIIKYWGKEDQSKMIPSTSSISLTLENMFTTTSVSFLPDTASSDQFYINGCLQDDKEHAKISAIIDQFRKPNQPFVKVETQNNMPTAAGLSSSSSGLSALVKACDQLFNTQLDQKALAQKAKFASGSASRSFFGPVAAWDKDSGDIYKVDTDLKMAMIMLVLNDAKKPISSRDGMKLCRETSTTFDEWIEKSAVDYQNMLTYLKANDFEKVGQLAESNALAMHTTTKTANPSFSYLTDESYQAMEAVKQLRQEGFSCYFTMDAGPNVKVLCLEKDLETLAARFEKDYRIIVSKTKDLPDA
>NC_012891.1|WP_012766841.1|818286_819165_+|mevalonate-kinase
MNEKIGYGKAHSKIILMGEHAVVYGYPAIALPLTDIEVVCHIFPADKPLVFDFYDTLSTAIYAALDYLQRLQEPIAYEIVSQVPQKRGMGSSAAVSIAAIRAVFSYCQEPLSDDLLEILVNKAEIIAHTNPSGLDAKTCLSDHAIKFIRNIGFETIKIDLGAFLIIADTGVHGHTREAVGKVAQFEETNLPYLAKLGRLTEAVEQAITQKDNQTIGQLMTQAHSALKAIGVSITKADQLVDVALKAGALGAKMTGGGLGGCMIALADTKEMAETISHKLQEEGAVNTWIQML
>NC_012891.1|WP_012766840.1|816339_818082_+|ABC-transporter-ATP-binding-protein
MALFKRLLSEIKVAKAAFATGIGLLLLATAAGQIAPLLLKQLIDHYLTPLAKGKSIILAHFKQLSWLYLALIIGSALLRYVSYRSLVYSSNKVVTQLRKQAFDVMQRLPISYFDHQPAGKIATRIINDTETLRNQFYDNLLSQIIISMAQIIFIYGVMIYLDLRSGLLLLLVIPIFYGIQVLYKRLTDQPMKAFYDARSAVNTQVNETMNGVSIIQLFHQENRMLEDFNQQINQMKKADDKIIFADSVASWTLTELVKYTMISAILAFIGYQFLQGKPGITVGKLFIYLNYLTRLFDILGTMVRQLPNIQRSQATGSRLMALLDQELEEDNPKEIHIDKGNVSFNHVSFAYEEGKNVLTDITIEAKQGETIALVGHTGSGKSSIMNLLYRFYTPQSGMITVDGQDIQAYSRESLRSQMGIVLQDPYLFSGTIASNVTMGNQSYSDQEVIEALEKVGAGPMIGRLDKGIHEPVYEKGASYSSGERQLIAFARTLITNPKILILDEATSHIDTETEEIIQRAMEVLKQGRTTFIIAHRLSTIQSANTILVLDKGRIVEHGNHQELLAKGGIYAQLSKLQEKV
>NC_012891.1|WP_041788951.1|814616_816338_+|ABC-transporter-ATP-binding-protein
MLSLMSRYIKQNKWTYIIIALTLFVYDASLIIPTKVIQSLIDAMSRYQLTQVSLMSHVLVLLGATILSYATAYVWHLKLFQEAVHFKFDLQQRAFRKLVFMRTPFYEKFRSGDMMTRFSTDVEALMDFIGYGLMIILYAGGMIAFIIPTMFLISWQMSLIGMIPISIMMVITYFITKKQEVLVEDARETISNLSDEVLETVEGIRVMRAYSKKAYMENHFAQKAEALADRWNRIAGYRGLYFPVYSVMIAISTLIILTVGLHFISKGEVSLGQVIALQLYLVSLVEPFAMLSDFILVYQTGRTSFRKINELIETGDDLEEDGHLKLESYDQIRLADYSFSYAKSSKPSLSAINLVLNKGETLGIVGKTGSGKTTLVRQLLRQYPVGQGQFYINGHHVLEYQRHALEEHIGYVPQEHVLFSKTVSENIAMGKEDATLEDILAAIATASFTDDLKGLSKGLDTKIGERGLSISGGQKQRISIARAFLSEPDLLILDDSLSAVDAKTETEIITHIQEERQGKTTIIVSHRLSAIQHADWVIVMDQGRIVEEGKPDQLLAQKGWYYEQYQRQQAQED
>NC_012891.1|WP_041788944.1|811797_813030_+|HAMP-domain-containing-histidine-kinase
MFNRIRIRFIMIASIAIFIILSSIVGIINTARCYQSQQEINRILHLISSNKGKLPGTTESSKRLGTKLSEDSLSQFRYYSVIFNANGHLLSSNTANISALDREEAQYFARLFAKSGEEKGSYRHQDSVYSYLITQLPNEEKLVVILDTTFYFRSVGDLLAVSVMLAFGGFIFFVVLVSLFSGMVIKPFVQNYEKQRRFITNAGHELKTPLAIISANNELVELMTGESEWTKSTSDQVKRLTGLINQMITLARLEEQPDVVLHMVDFSAIAQDAAEDFKSLVLKDGKRFDLTIQPNIMIKAEEKSLFELVTILVDNANKYCNPKGLVKVSLTTIGRRRKRAKLEVSNTYLEGKSIDYSRFFERFYREDESHNSKEKGYGIGLSMAESMVKLFKGTITVNYKNDAIVFTVVI
>NC_012891.1|WP_002984985.1|811120_811789_+|response-regulator-transcription-factor
MKILLAEDEWQMSNVLTTAMTHQGYDVDVVFNGQEAIDKAKDNAYDIMILDIMMPIKSGIEALKEIRASGNCSHIIMLTAMAEINDRVTGLDAGADDYLTKPFSLKELLARLRSMERRVESFTPQVLQFAGVTLNINEQELSAGNAIRLASKEGKLMAFLMLNQGKYLDTKTLYQHVWSDQEDYDTSIVWVYISYLRQKLLAIQANVIIAGDKDTSYCLLEK
>NC_012891.1|WP_041788963.1|829359_830877_-|helix-turn-helix-domain-containing-protein
MIQDYIEGKLTEQVTLLNALLDFQDIHLSQLATLVNAGEKKVADTLKDLVLLYEDQLSWTIKGGQVQLETSILDNKLHYFYAIYQNSLFLQTLHFFLDPKQKDFSDFSQSQFVSTATAYRLKKKCLNFLKEVGLIIRHNQIAGSEHRMRFLIALLHYRYGFPIYEFAKKDLDLVKDIIVTSNKTLNLAILENTPEEYQFFSYLVILSWYRHDYPLSDFCDHNLEHLKSIFIFDRVSTICSRVLEPKLGIQFSEREREYLFLAYCTTNNALYKDQWLVSDKKEMLQIVRLDTDIKYLLPHCEALFGSQISTSNSFTVACMFLMQNYLCGMQGLLPEGFFGHYHLDEEDHILLSIVTHLLDNWLKVLGIEEHNNTVACYLLTVHLRELIKLHLEPVPVYVFANNIADLSLLQTYLKLNFPTSVADIYGINILTSPCLESLNQKKGIILSDLRNRDYLKNLYQQQDHHFINFSMSFHALSQTVIAETIAKLRQENYQTFLNQLYSTLQ
>NC_012891.1|WP_012766848.1|831064_832342_-|hydroxymethylglutaryl-CoA-reductase,-degradative
MTNMNLNWAGFSKKTFEERLQLIKQFELLTPEHLQTLEEDCLLPIETANQLTENVLGRFALPFSIAPDFLINGVSYQVPFVTEEPSVVAAASFAAKLIKRSGGFASKVLKRQMIGQVALYDIDQVEEAKQTILANSDKLIAAANDAYPSIVKRGGGAREIRLEEKGDFLIFYLTVDTQEAMGANMVNTMMEALIPDLESLSKGQSLMAILSNYATESLVTASCQVDIRFLSRDKTEAQQLAKKMVLASQLAQADSYRAATHNKGIFNGIDAVVMATGNDWRAIEAGGHAYASRNGAYQGLSHWEFDQEQEVLLGQLTLPMPIASKGGSIGLNPTVSIAHDLLNQPDAKTLAQVIVSVGLAQNFAALKALTSSGIQAGHMKLHAKSLALLAGAKEEEVAPLVTSLLADKPMNLEKASQHLAILRNA
>NC_012891.1|WP_003062183.1|832322_833504_-|hydroxymethylglutaryl-CoA-synthase
MKIGIDKIGFATSQYVLKLDDLALARQTDPAKFSQGLLIEALSVTPVTEDIVTLAASAADQILTDEDKATIDMVILATESSVDQSKAAAIYVHHLMGIQPFARSFEVKEACYSATAALDYAKLHVAAKPESRVLVIASDIAKYGIDSAGESTQGAGSIAMLITANPRILELHQDNVAQTRDIMDFWRPNYSTTPFVNGVYSTKQYLDSLETTWQAYQDKTGAQLTDFAAFCFHLPFPKLALKGLNKMMDESLPVEHKEHLLENFQASITYSKQIGNIYTGSLYLGLLSLLENSKTLQAGDRIGLFSYGSGAVSEIFSGQLVAGYEQMLMTNRQTILDQRHRLSVAEYEELFYEEAKLDEQGNASFNTYLTSKFALTEIKDNQRLYQINDKYES
>NC_012891.1|WP_171841606.1|833691_834714_-|IS30-family-transposase
MSNINSTRKSSYSHLSATERGEIAAYLKMGKKPVEIARLLGRHRSTICREIKRGSVEQVKDKNGKQTFFNAYFADSGQRVYETNRQKSSYLKLNGCSARFIAQLESALTANIRLHSVDSFVQTYKVNHPEEVVPSTKTIYRYIKEGLLAIKPIDLPKMVSIRKRSKKVMKTNKKTLGKSIEERPEYINDRSEFGHWEIDLILGKKTKGEAVMLTLVERQTRYALGVKLEDKQSQTINRAVTHLISQYPIASITADNGSEFSLLSTLEAVDVYFAHPYSSHERGTNENFNGLLREYVPKGISLNPLTSEELDNYLTAINERPRRLLQYQSSTFLFELARTA
>NC_012891.1|WP_003054196.1|834898_835738_+|thymidylate-synthase
MTKADDIFKANIEKIMDEGVFSEQARPKYKDGRTANSKYITGAFAEYDLAKGEFPITTLRPIPIKSAIKELLWIYQDQTNSLDVLENKYNVHYWNEWEVGQTRTIGQRYGAVVKKHDIISKLLKQLAENPWNRRNVISLWDYEAFEETEGLLPCAFQTMFDVRRVGEDLYLDATLTQRSNDMLVAHHINAMQYVALQMMIAKHFGWKVGKFFYFVNNLHIYDNQFPQAKELLKRQPTDCQPKLVLNVPDGTNFFDIKPEDFELQDYEPVTPQLRFDLAI
>NC_012891.1|WP_003054187.1|835818_836316_+|dihydrofolate-reductase
MTKEMIAIWAEDEAGLIGVDGKLPWYLPRELQHFKETTLNQAILMGRVTFDGMNRRLLPNRQTLVMTRDVNYQVDGVLTMTSVEEVLDWYHAQEKTLYVIGGSKVLEAFDGYFNRVIKTVVHHQFEGDTYRPKLDLSRFREESQTFYPKDANNPYDFTVTVLKHQ
>NC_012891.1|WP_003054200.1|836335_836506_+|hypothetical-protein
MQRSIFGVFTAFLCAICVLCAIPAFRKNRYGLGTLFLLNAFTNLVNSIHAFYGTLF
>NC_012891.1|WP_003054192.1|836619_837849_+|ATP-dependent-Clp-protease-ATP-binding-subunit-ClpX
MAGNRTNDIKVYCSFCGKSQDEVKKIIAGNNVFICNECVALSQEIIKEELAEEVLADLTEVPKPKELLEVLNQYVVGQDRAKRALSVAVYNHYKRVSFTESRDDEDVELQKSNILMIGPTGSGKTFLAQTLAKSLNVPFAIADATSLTEAGYVGEDVENILLKLIQAADYNVERAERGIIYVDEIDKIAKKGENVSITRDVSGEGVQQALLKIIEGTVASVPPQGGRKHPNQEMIQIDTKNILFIVGGAFDGIEDIVKQRLGEKVIGFGQNSRKIDDNASYMQEIISEDIQKFGLIPEFIGRLPVVAALEQLNTSDLIQILTEPRNALVKQYQALLSYDGVELAFDKEALEAIANKAIERKTGARGLRSIIEETMLDIMFEIPSQEDVTKVRITKAAVEGKSKPVLETA
>NC_012891.1|WP_012766850.1|837858_838458_+|YihA-family-ribosome-biogenesis-GTP-binding-protein
MAEEQVLNTHNASILLSAANKSHYPQDDLPEIALAGRSNVGKSSFINTMLGRKNLARTSSKPGKTQLLNFFNIDDKLRFVDVPGYGYAKVSKSERAKWGKMIEEYLTSRDNLRAVVSLVDLRHEPSKEDVQMYEFLKYYDIPVIIVATKADKIPRGKWNKHESMVKKTLGFDKTDCFIIFSSVDRVGIDEAWDTILEHL
>NC_012891.1|WP_012766851.1|838601_839345_+|hypothetical-protein
MTRVAIGHPARKCLLWDRCSALCVFIIFLALLTMLFVIRYRNSSIEGIWKTASIDQKLGDDFAKRLTGLHQSPLIDDSLLTSSEMILQVKNNKAHLNFRVQVEKAAFAERLASYHENELLKILKDNHLVIGDLSQEEQQIIDSSMPAHHELEMILDQAFEKLASNIGGHYDRKTGSLSAIILKGNVNRILHTIDISELTTGHISLSKGITTPNGYFDYIKFGRKLELLGDEKIIFKKITEKSASGTS

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Crispr_ID: NC_012891_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_012891_2

1173568-1174793

TypeII

II-A,II-B

Consensus_repeat	Method
GTTTTGGGACCATTCAAAACAACATAGCTCTAAAAC	CRISPRCasFinder
GTTTTGGGACCATTCAAAACAACATAGCTCTAAAAC	CRT
GTTTTGGGACCATTCAAAACAACATAGCTCTAAAAC	PILER-CR
GTTTTGGGACCATTCAAAACAACATAGCTCTAAAAC	PILER-CR

18 spacers

csn2,cas2,cas1,cas9

The CRISPR arrays of NC_012891_2

>merge|NC_012891|2|1173568-1174793|CRISPRCasFinder,CRT,PILER-CR,PILER-CR
GAATTGGGACCATTCAAAACAACATAGCTCTAAAACACAGTTAAATAGCTTTGGTATCTTGTCGATGTTTTGGGACCATTCAAAACAACATAGCTCTAAAACTCATCAAGGCTCTGCGCACCACCCAACGGAGTTTTGGGACCATTCAAAACAACATAGCTCTAAAACGCCTTAGGAAACAAAGCATTTACACTACCAGTTTTGGGACCATTCAAAACAACATAGCTCTAAAACAAAAGTGGCTATCACGCTGACACAGACTAAGTTTTGGGACCATTCAAAACAACATAGCTCTAAAACAACACTGATTGTTCCAATTGTATTTGTAAAGTTTTGGGACCATTCAAAACAACATAGCTCTAAAACGTCACGCTGATATATGTCACCCAAATATAGGTTTTGGGACCATTCAAAACAACATAGCTCTAAAACACGCTTTAGCAGATGGAGCGGGGCTTACGAGGGTTTTGGGACCATTCAAAACAACATAGCTCTAAAACGCAAAAGCTTTCTCATATTTTACTCGATTCGTTTTGGGACCATTCAAAACAACATAGCTCTAAAACAGTATTCCAGTTCTCCATCAAGTAGTTCTCGTTTTGGGACCATTCAAAACAACATAGCTCTAAAACAATACAATCTCATGATTCGCAAACATCATGGTTTTGGGACCATTCAAAACAACATAGCTCTAAAACCATATTCTATTAATCCTTTATTTAAAAAATGTTTTGGGACCATTCAAAACAACATAGCTCTAAAACGCAACAGTGTTTTCACGGTGGTTGCACGCCGTTTTGGGACCATTCAAAACAACATAGCTCTAAAACAAGCATCATAGTAAACATATCTAGCACGCTGTTTTGGGACCATTCAAAACAACATAGCTCTAAAACATGCTCAAAAAGATGTGCTGTCCAACAGTAGTTTTGGGACCATTCAAAACAACATAGCTCTAAAACAAAGACGGTTTTTACTTTCAAAAATGAGATGTTTTGGGACCATTCAAAACAACATAGCTCTAAAACATGGTACAAGTAAAACTACCGCCCCAGTTAGTTTTGGGACCATTCAAAACAACATAGCTCTAAAACCAGACTTGGAATTGGCCAATGAGCGTGCCGGTTTTGGGACCATTCAAAACAACATAGCTCTAAAACTTCTGTCTAGCCCTTGTTCTTGACTCGTCTGTTTTGGGACCATTCAAAACAACATAGCTCTAAAAC

>NC_012891|2|2|1173568-1174793|CRISPRCasFinder
GAATTGGGACCATTCAAAACAACATAGCTCTAAAAC	ACAGTTAAATAGCTTTGGTATCTTGTCGAT
GTTTTGGGACCATTCAAAACAACATAGCTCTAAAAC	TCATCAAGGCTCTGCGCACCACCCAACGGA
GTTTTGGGACCATTCAAAACAACATAGCTCTAAAAC	GCCTTAGGAAACAAAGCATTTACACTACCA
GTTTTGGGACCATTCAAAACAACATAGCTCTAAAAC	AAAAGTGGCTATCACGCTGACACAGACTAA
GTTTTGGGACCATTCAAAACAACATAGCTCTAAAAC	AACACTGATTGTTCCAATTGTATTTGTAAA
GTTTTGGGACCATTCAAAACAACATAGCTCTAAAAC	GTCACGCTGATATATGTCACCCAAATATAG
GTTTTGGGACCATTCAAAACAACATAGCTCTAAAAC	ACGCTTTAGCAGATGGAGCGGGGCTTACGAGG
GTTTTGGGACCATTCAAAACAACATAGCTCTAAAAC	GCAAAAGCTTTCTCATATTTTACTCGATTC
GTTTTGGGACCATTCAAAACAACATAGCTCTAAAAC	AGTATTCCAGTTCTCCATCAAGTAGTTCTC
GTTTTGGGACCATTCAAAACAACATAGCTCTAAAAC	AATACAATCTCATGATTCGCAAACATCATG
GTTTTGGGACCATTCAAAACAACATAGCTCTAAAAC	CATATTCTATTAATCCTTTATTTAAAAAAT
GTTTTGGGACCATTCAAAACAACATAGCTCTAAAAC	GCAACAGTGTTTTCACGGTGGTTGCACGCC
GTTTTGGGACCATTCAAAACAACATAGCTCTAAAAC	AAGCATCATAGTAAACATATCTAGCACGCT
GTTTTGGGACCATTCAAAACAACATAGCTCTAAAAC	ATGCTCAAAAAGATGTGCTGTCCAACAGTA
GTTTTGGGACCATTCAAAACAACATAGCTCTAAAAC	AAAGACGGTTTTTACTTTCAAAAATGAGAT
GTTTTGGGACCATTCAAAACAACATAGCTCTAAAAC	ATGGTACAAGTAAAACTACCGCCCCAGTTA
GTTTTGGGACCATTCAAAACAACATAGCTCTAAAAC	CAGACTTGGAATTGGCCAATGAGCGTGCCG
GTTTTGGGACCATTCAAAACAACATAGCTCTAAAAC	TTCTGTCTAGCCCTTGTTCTTGACTCGTCT
GTTTTGGGACCATTCAAAACAACATAGCTCTAAAAC

>NC_012891|2|1|1173568-1174793|CRT
GAATTGGGACCATTCAAAACAACATAGCTCTAAAAC	ACAGTTAAATAGCTTTGGTATCTTGTCGAT
GTTTTGGGACCATTCAAAACAACATAGCTCTAAAAC	TCATCAAGGCTCTGCGCACCACCCAACGGA
GTTTTGGGACCATTCAAAACAACATAGCTCTAAAAC	GCCTTAGGAAACAAAGCATTTACACTACCA
GTTTTGGGACCATTCAAAACAACATAGCTCTAAAAC	AAAAGTGGCTATCACGCTGACACAGACTAA
GTTTTGGGACCATTCAAAACAACATAGCTCTAAAAC	AACACTGATTGTTCCAATTGTATTTGTAAA
GTTTTGGGACCATTCAAAACAACATAGCTCTAAAAC	GTCACGCTGATATATGTCACCCAAATATAG
GTTTTGGGACCATTCAAAACAACATAGCTCTAAAAC	ACGCTTTAGCAGATGGAGCGGGGCTTACGAGG
GTTTTGGGACCATTCAAAACAACATAGCTCTAAAAC	GCAAAAGCTTTCTCATATTTTACTCGATTC
GTTTTGGGACCATTCAAAACAACATAGCTCTAAAAC	AGTATTCCAGTTCTCCATCAAGTAGTTCTC
GTTTTGGGACCATTCAAAACAACATAGCTCTAAAAC	AATACAATCTCATGATTCGCAAACATCATG
GTTTTGGGACCATTCAAAACAACATAGCTCTAAAAC	CATATTCTATTAATCCTTTATTTAAAAAAT
GTTTTGGGACCATTCAAAACAACATAGCTCTAAAAC	GCAACAGTGTTTTCACGGTGGTTGCACGCC
GTTTTGGGACCATTCAAAACAACATAGCTCTAAAAC	AAGCATCATAGTAAACATATCTAGCACGCT
GTTTTGGGACCATTCAAAACAACATAGCTCTAAAAC	ATGCTCAAAAAGATGTGCTGTCCAACAGTA
GTTTTGGGACCATTCAAAACAACATAGCTCTAAAAC	AAAGACGGTTTTTACTTTCAAAAATGAGAT
GTTTTGGGACCATTCAAAACAACATAGCTCTAAAAC	ATGGTACAAGTAAAACTACCGCCCCAGTTA
GTTTTGGGACCATTCAAAACAACATAGCTCTAAAAC	CAGACTTGGAATTGGCCAATGAGCGTGCCG
GTTTTGGGACCATTCAAAACAACATAGCTCTAAAAC	TTCTGTCTAGCCCTTGTTCTTGACTCGTCT
GTTTTGGGACCATTCAAAACAACATAGCTCTAAAAC

>NC_012891|2|1|1173634-1174067|PILER-CR
GTTTTGGGACCATTCAAAACAACATAGCTCTAAAAC	TCATCAAGGCTCTGCGCACCACCCAACGGA
GTTTTGGGACCATTCAAAACAACATAGCTCTAAAAC	GCCTTAGGAAACAAAGCATTTACACTACCA
GTTTTGGGACCATTCAAAACAACATAGCTCTAAAAC	AAAAGTGGCTATCACGCTGACACAGACTAA
GTTTTGGGACCATTCAAAACAACATAGCTCTAAAAC	AACACTGATTGTTCCAATTGTATTTGTAAA
GTTTTGGGACCATTCAAAACAACATAGCTCTAAAAC	GTCACGCTGATATATGTCACCCAAATATAG
GTTTTGGGACCATTCAAAACAACATAGCTCTAAAAC	ACGCTTTAGCAGATGGAGCGGGGCTTACGAGG
GTTTTGGGACCATTCAAAACAACATAGCTCTAAAACGCAAAAGCTTTCTCATATTTTACTCGATTCGTTTTGGGACCATTCAAAACAACATAGCTCTAAAACAGTATTCCAGTTCTCCATCAAGTAGTTCTCGTTTTGGGACCATTCAAAACAACATAGCTCTAAAACAATACAATCTCATGATTCGCAAACATCATGGTTTTGGGACCATTCAAAACAACATAGCTCTAAAACCATATTCTATTAATCCTTTATTTAAAAAATGTTTTGGGACCATTCAAAACAACATAGCTCTAAAACGCAACAGTGTTTTCACGGTGGTTGCACGCCGTTTTGGGACCATTCAAAACAACATAGCTCTAAAACAAGCATCATAGTAAACATATCTAGCACGCTGTTTTGGGACCATTCAAAACAACATAGCTCTAAAAC	ATGCTCAAAAAGATGTGCTGTCCAACAGTA
GTTTTGGGACCATTCAAAACAACATAGCTCTAAAAC	AAAGACGGTTTTTACTTTCAAAAATGAGAT
GTTTTGGGACCATTCAAAACAACATAGCTCTAAAAC	ATGGTACAAGTAAAACTACCGCCCCAGTTA
GTTTTGGGACCATTCAAAACAACATAGCTCTAAAAC	CAGACTTGGAATTGGCCAATGAGCGTGCCG
GTTTTGGGACCATTCAAAACAACATAGCTCTAAAAC	TTCTGTCTAGCCCTTGTTCTTGACTCGTCT


>NC_012891|2|2|1174428-1174793|PILER-CR
	TCATCAAGGCTCTGCGCACCACCCAACGGA
GTTTTGGGACCATTCAAAACAACATAGCTCTAAAAC	GCCTTAGGAAACAAAGCATTTACACTACCA
GTTTTGGGACCATTCAAAACAACATAGCTCTAAAAC	AAAAGTGGCTATCACGCTGACACAGACTAA
GTTTTGGGACCATTCAAAACAACATAGCTCTAAAAC	AACACTGATTGTTCCAATTGTATTTGTAAA
GTTTTGGGACCATTCAAAACAACATAGCTCTAAAAC	GTCACGCTGATATATGTCACCCAAATATAG
GTTTTGGGACCATTCAAAACAACATAGCTCTAAAAC	ACGCTTTAGCAGATGGAGCGGGGCTTACGAGG
GTTTTGGGACCATTCAAAACAACATAGCTCTAAAACGCAAAAGCTTTCTCATATTTTACTCGATTCGTTTTGGGACCATTCAAAACAACATAGCTCTAAAACAGTATTCCAGTTCTCCATCAAGTAGTTCTCGTTTTGGGACCATTCAAAACAACATAGCTCTAAAACAATACAATCTCATGATTCGCAAACATCATGGTTTTGGGACCATTCAAAACAACATAGCTCTAAAACCATATTCTATTAATCCTTTATTTAAAAAATGTTTTGGGACCATTCAAAACAACATAGCTCTAAAACGCAACAGTGTTTTCACGGTGGTTGCACGCCGTTTTGGGACCATTCAAAACAACATAGCTCTAAAACAAGCATCATAGTAAACATATCTAGCACGCTGTTTTGGGACCATTCAAAACAACATAGCTCTAAAAC	ATGCTCAAAAAGATGTGCTGTCCAACAGTA
GTTTTGGGACCATTCAAAACAACATAGCTCTAAAAC	AAAGACGGTTTTTACTTTCAAAAATGAGAT
GTTTTGGGACCATTCAAAACAACATAGCTCTAAAAC	ATGGTACAAGTAAAACTACCGCCCCAGTTA
GTTTTGGGACCATTCAAAACAACATAGCTCTAAAAC	CAGACTTGGAATTGGCCAATGAGCGTGCCG
GTTTTGGGACCATTCAAAACAACATAGCTCTAAAAC	TTCTGTCTAGCCCTTGTTCTTGACTCGTCT
GTTTTGGGACCATTCAAAACAACATAGCTCTAAAAC

Protein	Signature genes	Signature genes Name	Protein_function
NC_012891.1\|WP_012767095.1\|1167722_1168892_-\|DUF2974-domain-containing-protein	unknown	unknown	gnl\|CDD\|371412
NC_012891.1\|WP_002989934.1\|1165450_1165942_-\|PTS-system-mannose/fructose/N-acetylgalactosamine-transporter-subunit-IIB	unknown	unknown	gnl\|CDD\|225976
NC_012891.1\|WP_003058441.1\|1169081_1169378_-\|bacteriocin-immunity-protein	unknown	unknown	gnl\|CDD\|370205
NC_012891.1\|WP_012767110.1\|1183500_1184631_-\|oxygen-independent-coproporphyrinogen-III-oxidase	unknown	unknown	gnl\|CDD\|236309
NC_012891.1\|WP_003058431.1\|1169377_1169608_-\|bacteriocin	unknown	unknown	gnl\|CDD\|366773
NC_012891.1\|WP_003060137.1\|1172993_1173452_-\|nucleoside-diphosphate-kinase	unknown	unknown	gnl\|CDD\|179085
NC_012891.1\|WP_041789028.1\|1174895_1175558_-\|type-II-A-CRISPR-associated-protein-Csn2	csn2	cd09758_csn2_CAS-II-A	gnl\|CDD\|213408
NC_012891.1\|WP_002984855.1\|1184692_1185334_-\|hypothetical-protein	unknown	unknown	unknown
NC_012891.1\|WP_012767109.1\|1182738_1183491_-\|acyl-[acyl-carrier-protein]-thioesterase	unknown	unknown	gnl\|CDD\|226401
NC_012891.1\|WP_003056620.1\|1185457_1186813_-\|phosphoglucosamine-mutase	unknown	unknown	gnl\|CDD\|237670
NC_012891.1\|WP_012767105.1\|1175885_1176755_-\|type-II-CRISPR-associated-endonuclease-Cas1	cas1	cd09720_cas1_CAS-II-A:CAS-II-B:CAS-II-C	gnl\|CDD\|187851
NC_012891.1\|WP_012767097.1\|1169815_1170466_-\|HD-domain-containing-protein	unknown	unknown	gnl\|CDD\|224336
NC_012891.1\|WP_003054515.1\|1181974_1182739_-\|TIGR01457-family-HAD-type-hydrolase	unknown	unknown	gnl\|CDD\|319832
NC_012891.1\|WP_003062642.1\|1166592_1167612_-\|YeiH-family-putative-sulfate-export-transporter	unknown	unknown	gnl\|CDD\|225411
NC_012891.1\|WP_041789030.1\|1181345_1181975_-\|TIGR01906-family-membrane-protein	unknown	unknown	gnl\|CDD\|226884
NC_012891.1\|WP_003062486.1\|1170478_1170916_-\|peptide-methionine-(R)-S-oxide-reductase-MsrB	unknown	unknown	gnl\|CDD\|234692
NC_012891.1\|WP_012767106.1\|1176754_1180870_-\|type-II-CRISPR-RNA-guided-endonuclease-Cas9	cas9	COG3513_cas9_CAS-II-A:CAS-II-B:CAS-II-C	gnl\|CDD\|226044
NC_012891.1\|WP_003060515.1\|1165960_1166386_-\|PTS-mannose-transporter-subunit-IIA	unknown	unknown	gnl\|CDD\|225446
NC_012891.1\|WP_012767104.1\|1175547_1175889_-\|CRISPR-associated-endonuclease-Cas2	cas2	COG3512_cas2_CAS-II-A:CAS-II-B:CAS-II-C	gnl\|CDD\|226043
NC_012891.1\|WP_012767098.1\|1171091_1172924_-\|elongation-factor-4	unknown	unknown	gnl\|CDD\|235462

Protein	Function_ID	Function_description	E-value
NC_012891.1\|WP_012767095.1\|1167722_1168892_-\|DUF2974-domain-containing-protein	gnl\|CDD\|371412	pfam11187, DUF2974, Protein of unknown function (DUF2974). This bacterial family of proteins has no known function.	8.10306e-78
NC_012891.1\|WP_002989934.1\|1165450_1165942_-\|PTS-system-mannose/fructose/N-acetylgalactosamine-transporter-subunit-IIB	gnl\|CDD\|225976	COG3444, COG3444, Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IIB [Carbohydrate transport and metabolism].	8.80769e-55
NC_012891.1\|WP_003058441.1\|1169081_1169378_-\|bacteriocin-immunity-protein	gnl\|CDD\|370205	pfam08951, EntA_Immun, Enterocin A Immunity. Gram-positive lactobacilli produce bacteriocins to kill closely-related competitor species. To protect themselves from the bacteriocidal activity of this molecule they co-express an immunity protein (for discussion of this operon see Bacteriocin_IIc pfam10439). The immunity protein structure is a soluble, cytoplasmic, antiparallel four alpha-helical globular bundle with a fifth, more flexible and more divergent C-terminal helical hair-pin. The C-terminal hair-pin recognizes the C-terminus of the producer bacteriocin and this interaction is sufficient to dis-orient the bacteriocin within the membrane and close up the permeabilising pore that on its own the bacteriocin creates. These immunity proteins interact in the same way with other bacteriocins, family Bacteriocin_II, pfam01721. Since many enterococci can produce more than one bacteriocin it seems likely that the whole operon can be carried on transferable plasmids.	0.000236171
NC_012891.1\|WP_012767110.1\|1183500_1184631_-\|oxygen-independent-coproporphyrinogen-III-oxidase	gnl\|CDD\|236309	PRK08599, PRK08599, oxygen-independent coproporphyrinogen III oxidase.	0
NC_012891.1\|WP_003058431.1\|1169377_1169608_-\|bacteriocin	gnl\|CDD\|366773	pfam01721, Bacteriocin_II, Class II bacteriocin. The bacteriocins are small peptides that inhibit the growth of various bacteria. Bacteriocins of lactic acid bacteria may inhibit their target cells by permeabilising the cell membrane.	2.52035e-05
NC_012891.1\|WP_003060137.1\|1172993_1173452_-\|nucleoside-diphosphate-kinase	gnl\|CDD\|179085	PRK00668, ndk, mulitfunctional nucleoside diphosphate kinase/apyrimidinic endonuclease/3'-; Validated.	5.05917e-75
NC_012891.1\|WP_041789028.1\|1174895_1175558_-\|type-II-A-CRISPR-associated-protein-Csn2	gnl\|CDD\|213408	cd09758, Csn2, CRISPR/Cas system-associated protein Csn2. Csn2 is a Nmeni subtype-specific Cas protein, which may function in the adaptation process which mediates the incorporation of foreign nucleic acids into the microbial host genome. Csn 2 may interact directly with double-stranded DNA. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA. Csn2 has been predicted to be a functional analog of Cas4 based on anti-correlated phyletic patterns; also known as SPy1049 family.	9.41873e-121
NC_012891.1\|WP_012767109.1\|1182738_1183491_-\|acyl-[acyl-carrier-protein]-thioesterase	gnl\|CDD\|226401	COG3884, FatA, Acyl-ACP thioesterase [Lipid metabolism].	1.70587e-108
NC_012891.1\|WP_003056620.1\|1185457_1186813_-\|phosphoglucosamine-mutase	gnl\|CDD\|237670	PRK14316, glmM, phosphoglucosamine mutase; Provisional.	0
NC_012891.1\|WP_012767105.1\|1175885_1176755_-\|type-II-CRISPR-associated-endonuclease-Cas1	gnl\|CDD\|187851	cd09720, Cas1_II, CRISPR/Cas system-associated protein Cas1. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas1 is the most universal CRISPR system protein thought to be involved in spacer intergration. Cas1 is metal-dependent deoxyribonuclease, also binds RNA; Shown to possess a unique fold consisting of a N-terminal beta-strand domain and a C-terminal alpha-helical domain.	3.47501e-131
NC_012891.1\|WP_012767097.1\|1169815_1170466_-\|HD-domain-containing-protein	gnl\|CDD\|224336	COG1418, COG1418, Predicted HD superfamily hydrolase [General function prediction only].	9.0259e-34
NC_012891.1\|WP_003054515.1\|1181974_1182739_-\|TIGR01457-family-HAD-type-hydrolase	gnl\|CDD\|319832	cd07530, HAD_Pase_UmpH-like, UmpH/NagD family phosphatase, similar to Escherichia coli UmpH UMP phosphatase/NagD nucleotide phosphatase and Mycobacterium tuberculosis Rv1692 glycerol 3-phosphate phosphatase. Escherichia coli UmpH/NagD is a ribonucleoside tri-, di-, and monophosphatase with a preference for purines, it shows peak activity with UMP and functions in UMP-degradation. It is also an effective phosphatase with AMP, GMP and CMP. Mycobacterium tuberculosis phosphatase, Rv1692 is a glycerol 3-phosphate phosphatase. Rv1692 is the final enzyme involved in glycerophospholipid recycling/catabolism. This subfamily belongs to the UmpH/NagD phosphatase family, and to the haloacid dehalogenase-like (HAD) hydrolases, a large superfamily of diverse enzymes that catalyze carbon or phosphoryl group transfer reactions on a range of substrates, using an active site aspartate in nucleophilic catalysis. Members of this superfamily include 2-L-haloalkanoic acid dehalogenase, azetidine hydrolase, phosphonoacetaldehyde hydrolase, phosphoserine phosphatase, phosphomannomutase, P-type ATPases and many others. HAD hydrolases are found in all three kingdoms of life, and most genomes are predicted to contain multiple HAD-like proteins. Members possess a highly conserved alpha/beta core domain, and many also possess a small cap domain, the fold and function of which is variable. HAD hydrolases are sometimes referred to as belonging to the DDDD superfamily of phosphohydrolases.	4.34174e-127
NC_012891.1\|WP_003062642.1\|1166592_1167612_-\|YeiH-family-putative-sulfate-export-transporter	gnl\|CDD\|225411	COG2855, COG2855, Predicted membrane protein [Function unknown].	8.42758e-103
NC_012891.1\|WP_041789030.1\|1181345_1181975_-\|TIGR01906-family-membrane-protein	gnl\|CDD\|226884	COG4478, COG4478, Predicted membrane protein [Function unknown].	1.94922e-80
NC_012891.1\|WP_003062486.1\|1170478_1170916_-\|peptide-methionine-(R)-S-oxide-reductase-MsrB	gnl\|CDD\|234692	PRK00222, PRK00222, peptide-methionine (R)-S-oxide reductase MsrB.	2.05206e-85
NC_012891.1\|WP_012767106.1\|1176754_1180870_-\|type-II-CRISPR-RNA-guided-endonuclease-Cas9	gnl\|CDD\|226044	COG3513, COG3513, Predicted CRISPR-associated nuclease, contains McrA/HNH-nuclease and RuvC-like nuclease domain [Defense mechanisms].	0
NC_012891.1\|WP_003060515.1\|1165960_1166386_-\|PTS-mannose-transporter-subunit-IIA	gnl\|CDD\|225446	COG2893, ManX, Phosphotransferase system, mannose/fructose-specific component IIA [Carbohydrate transport and metabolism].	4.93402e-30
NC_012891.1\|WP_012767104.1\|1175547_1175889_-\|CRISPR-associated-endonuclease-Cas2	gnl\|CDD\|226043	COG3512, COG3512, CRISPR-associated protein, Cas2 homolog [Defense mechanisms].	4.20536e-57
NC_012891.1\|WP_012767098.1\|1171091_1172924_-\|elongation-factor-4	gnl\|CDD\|235462	PRK05433, PRK05433, GTP-binding protein LepA; Provisional.	0

>NC_012891.1|WP_003060137.1|1172993_1173452_-|nucleoside-diphosphate-kinase
MEQTFFMIKPDGVERGLVGEVLRRIERRGFTFERLELRQASPELLAKHYEALVTKPFYPELEAYMTSGPVLIGVLSGNRVISSWRTMMGVTNPKDALPGTIRGDFAQAPGDDGGIFNVVHGSDSRDSARREIALWFNQAELDSSAIFPKDNQ
>NC_012891.1|WP_012767098.1|1171091_1172924_-|elongation-factor-4
MNSQDLKKRQEKIRNFSIIAHIDHGKSTLADRILEKTETVSSREMQAQLLDSMDLERERGITIKLNAIELNYTAKDGETYIFHLIDTPGHVDFTYEVSRSLAACEGAILVVDAAQGIEAQTLANVYLALDNDLEILPVINKIDLPAADPERVRHEVEDVIGLDASEAVLASAKAGIGIEEILEQIVEKVPAPTGDVDAPLQALIFDSVYDAYRGVILQVRIVNGIVKPGDKIQMMSNGKTFDVTEVGIFTPKAVGRDFLATGDVGYVAASIKTVADTRVGDTVTLANNPAKEALHGYKQMNPMVFAGIYPIESNKYNDLREALEKLQLNDASLQFEPETSQALGFGFRCGFLGLLHMDVIQERLEREFNIDLIMTAPSVVYHVHTTDGDMIEVSNPSEFPDPTRVASIEEPYVKAQIMVPQEFVGAVMELSQRKRGDFVTMDYIDDNRVNVIYQIPLAEIVFDFFDKLKSSTRGYASFDYEISEYRKSQLVKMDILLNGDKVDALSFIVHKEFAYERGKIIVEKLKKIIPRQQFEVPIQAAIGQKIVARSDIKALRKNVLAKCYGGDVSRKRKLLEKQKAGKKRMKSIGSVEVPQEAFLSVLSMDEDAKK
>NC_012891.1|WP_003062486.1|1170478_1170916_-|peptide-methionine-(R)-S-oxide-reductase-MsrB
METKDDLKKRIGDLSYEVTQHAATERPFTGKYDDFFEKGIYVDIVSGEVLFSSLDKFNSGCGWPAFSKPIENRMVTNHDDSSYGMRRVEVKSREAGSHLGHVFSDGPQEAGGLRYCINSAALKFIPYDQMEKEGYAQWLTLFDEK
>NC_012891.1|WP_012767097.1|1169815_1170466_-|HD-domain-containing-protein
MTEKEAQLLAQAEAWVKEKLAADASGHDFWHVIRVCRLAKIIAQEEEGDVFICQLAALLHDMADDKLNADPKKARQDILAWLAGHDVSQKQSDQVMTIIDTISFKGGHGKPLTNLEAKIVQDADRLDAIGAIGIARCMVYSGHTGRLIHDPDRLPRETMTVEEYRKDGTAIMHFYEKLLTLKERMNTAYGRQLAEHRHQVLVSYLDEFYAEWDGLR
>NC_012891.1|WP_003058431.1|1169377_1169608_-|bacteriocin
MNTKIFEKFDFMDNEKLAYIDGGAGSGKTVYQGNGLYCNKVKCWVNWAETWTTIANNSVMNVLTGGNAGWHSGGAL
>NC_012891.1|WP_003058441.1|1169081_1169378_-|bacteriocin-immunity-protein
MSGLNWFSGGNERQQQASLLIKDLVADLKQSGGKEPLQKVLLSFDEELKRGESSIPFILSRMTVAVSTVLKEHQITLSAKESDQLDDLYALLQIRYGY
>NC_012891.1|WP_012767095.1|1167722_1168892_-|DUF2974-domain-containing-protein
MATLLDYIKTNGNRDYHSLALNELDVAVINEIGYLAFDELVADDNHLEATIKLSQLPLLQTREIKGDPYDFLNTKERLDLFQMMCQSKRFSELTLSHYINDINTEFEKQFAAMVFRLPSIDYTQLVFRGTDDSLIGWKEDFKLTYMREIPAHRSAIDYIKTYHTYYPNQKLVLSGHSKGGNLALYAASFVPKNVQASLKDIYLFDSPGLIKEFLTHPGYQAIRRRLVVIKPQDAIIGVMLYCDVPEKIVQSQSYGLLQHQMVNWQITPNAQFKRAPKRSALSYDLEETFKDWTNQLSKQDLKLLCDTFFDCLASSGITSLNVFSLDDKAFLTLMRVISSLQSIDHEKKKVMVKSLHQLMVTYGSYRRRDISENIHNHLQQLLTLTKGIK
>NC_012891.1|WP_003062642.1|1166592_1167612_-|YeiH-family-putative-sulfate-export-transporter
MSTYLRKLPGLLLCLLLALPAWYLGRLFPIIGAPVFAILLGMLLALFYHHRDKTKEGISFTSKYILQTAVVLLGFGLNLTQVMAVGMQSLPIIVSTVATALLVAYGLQKWLGLDVNTATLVGVGSSICGGSAIAATAPVIKAKDDEIAKAISVIFLFNILAALLFPSLGQLLGLSNEGFAIFAGTAVNDTSSVTATATAWDAIHHSNTLDGATIVKLTRTLAIIPITLGLSLYRAKKEHENVTEEGFSLSKSFPRFILFFLLASLITTLMTSFGLSADVFHSLKELSKFFIVMAMAAIGLNTNLVKLIKTGGQAILLGAICWVAITLVSLGMQFALGIW
>NC_012891.1|WP_003060515.1|1165960_1166386_-|PTS-mannose-transporter-subunit-IIA
MKRKFLIGSHGRLASGLQSSIDILAGMGQTLETIDAYVDDSDYTSRIDDFIAGVAADEQGLIFTDLLGGSVNQKMVTAVMNSGKDNIFLITNSNLATLLSLVFLKPGEALTKDEIVTVINESQVQLVDLVPETNSEDDFFD
>NC_012891.1|WP_002989934.1|1165450_1165942_-|PTS-system-mannose/fructose/N-acetylgalactosamine-transporter-subunit-IIB
MITQIRVDDRLIHGQVAVVWTKELNAPLLVVANDEAAKNEITQMTLKMAVPNGMKLLIRSVEDSIKLFNDPRATDKRIFVIVNSVKDACAIAKEVPDLEAVNVANVGRFDKSDPASKVKVTPSLLLNPEEMAAAKELVSLPELDVFNQVLPSNTKVHLSQLVN
>NC_012891.1|WP_041789028.1|1174895_1175558_-|type-II-A-CRISPR-associated-protein-Csn2
MNLNFPLLDEPIPLRGGTILVLEDVCVFSKIVQYCYQYEEDSELKFFDHKMKTIKESEIMLVTDILGFDVNSSTILKLIHADLESQFNEKPEVKSMIDKLVATITELIVFECLENELDLEYDEITILELIKSLGVKVETQSDTIFEKCLEILQIFKYLTKKKLLIFVNSGAFLTKDEVASLQEYISLTNLTVLFLEARELYDFPQYILDEDYFLITKNMV
>NC_012891.1|WP_012767104.1|1175547_1175889_-|CRISPR-associated-endonuclease-Cas2
MSYRYMRMILMFDMPTDTAEERKVYRKFRKFLLSEGFIMHQFSIYSKLLLNNTANNAMIGRLREHNPHKGNITLLTVTEKQFARMIYLHGERNNCIANSDERLVFLGEAFDES
>NC_012891.1|WP_012767105.1|1175885_1176755_-|type-II-CRISPR-associated-endonuclease-Cas1
MAGWRTVVVNTHSKLSYKNNHLIFKDAYKTELIHLSEIDILLLETTDIVLSTMLVKRLVDENVLVIFCDNKRLPTAMLMPFYGRHDSSLQLGKQMSWSEEVKSEVWTTIIAQKILNQSCYLGVCSYFEKSQSIMDLYHGLELFDPSNREGHAARIYFNTLFGNDFSREQDNVINAGLDYGYTLLLSMFAREVVVSGCMTQFGLKHANQFNQFNFASDIMEPFRPLVDKIIFENRNQPFPKIKRELFTLFSDTFLYNGKEMYLTNIVSDYTKKVVKALNNEGKGVPEFRI
>NC_012891.1|WP_012767106.1|1176754_1180870_-|type-II-CRISPR-RNA-guided-endonuclease-Cas9
MDKKYSIGLDIGTNSVGWAVITDDYKVPSKKFKVLGNTDRHSIKKNLIGALLFDSGETAEATRLKRTARRRYTRRKNRIRYLQEIFSSEMSKVDDSFFHRLEESFLVEEDKKHERHPIFGNIVDEVAYHEKYPTIYHLRKKLADSTDKADLRLIYLALAHMIKFRGHFLIEGDLNPDNSDMDKLFIQLVQTYNQLFEENPINASRVDAKAILSARLSKSRRLENLIAQLPGEKRNGLFGNLIALSLGLTPNFKSNFDLAEDAKLQLSKDTYDDDLDNLLAQIGDQYADLFLAAKNLSDAILLSDILRVNSEITKAPLSASMIKRYDEHHQDLTLLKALVRQQLPEKYKEIFFDQSKNGYAGYIDGGASQEEFYKFIKPILEKMDGTEELLAKLNREDLLRKQRTFDNGSIPHQIHLGELHAILRRQEDFYPFLKDNREKIEKILTFRIPYYVGPLARGNSRFAWMTRKSEETITPWNFEEVVDKGASAQSFIERMTNFDKNLPNEKVLPKHSLLYEYFTVYNELTKVKYVTEGMRKPEFLSGKQKEAIVDLLFKTNRKVTVKQLKEDYFKKIECFDSVEISGVEDRFNASLGTYHDLLKIIKDKDFLDNEENEDILEDIVLTLTLFEDKEMIEERLKKYANLFDDKVMKQLKRRHYTGWGRLSRKLINGIRDKQSGKTILDFLKSDGFANRNFMQLINDDSLTFKEAIQKAQVSGQGHSLHEQIANLAGSPAIKKGILQSVKVVDELVKVMGHKPENIVIEMARENQTTQKGQKNSRERMKRIEEGIKELGSQILKEHPVENTQLQNEKLYLYYLQNGRDMYVDQELDINRLSDYDVDHIVPQSFIKDDSIDNKILTRSDKNRGKSDNVPSEEVVKKMKNYWRQLLNAKLITQRKFDNLTKAERGGLSELDKAGFIKRQLVETRQITKHVAQILDSRMNTKYDENDKLIREVKVITLKSKLVSDFRKDFQFYKVREINNYHHAHDAYLNAVVGTALIKKYTKLESEFVYGDYKVYDVRKMIAKSEQEIGKATAKRFFYSNIMNFFKTEITLANGEIRKRPLIETNEETGEIVWDKGRDFATVRKVLSMPQVNIVKKTEVQTGALTNESIYARGSFDKLISRKHRFESSKYGGFGSPTVTYSVLVVAKSKVQDGKVKKIKTGKELIGMTLLDKLVFEKNPLKFIEDKGYGNVQIDKCIKLPKYSLFEFENGTRRMLASVMANNNSRGDLQKANEMFLPAKLVTLLYHAHKIESSKELEHEAYILDHYNDLYQLLSYIERFASLYVDVEKNISKVKELFSNIESYSISEICSSVINLLTLTASGAPADFKFLGTTIPRKRYGSPQSILSSTLIHQSITGLYETRIDLSQLGGD
>NC_012891.1|WP_041789030.1|1181345_1181975_-|TIGR01906-family-membrane-protein
MVENTKLLCSWLWLLALAILMTIYSAWLWYPLEVDHLKLEQVVFMSKDAILHNYNGLLNYLTNPFETSLTFASFRSSTDGLKHFADVKWLFHLTQVVFLGLLYPTVKDFKQRFKTKSFWSIQRPLMIAALFPLMIGLMASVIGFENFFTLFHKVLFVGDSNWLFDPLKDPVIWILPEVFFLHCFLFFMTVYEIILWSLVGLARWQRPKI
>NC_012891.1|WP_003054515.1|1181974_1182739_-|TIGR01457-family-HAD-type-hydrolase
MPYKGYLIDLDGTIYQGKNRIPAGERFIKRLQEKGLPYLLVTNNTTRTPEMVQDMLSKQFNVETGIETIYTATMATVDYMNDMNRGKTAYVIGETGLKSAIAAAGYVEELENPAYVVVGLDSQVTYDMLATATLAIQKGALFIGTNPDLNIPTERGLMPGAGALNALLEAATRVKPVFIGKPNAIIMNKSLEVLGIQRSEAVMVGDNYLTDIMAGIQNDIATILVTTGFTRPEEVPTLPIQPDHVLSSLDEWRL
>NC_012891.1|WP_012767109.1|1182738_1183491_-|acyl-[acyl-carrier-protein]-thioesterase
MGLSYREDIKLPFELCDVKSDIKFPLLLDYCLTVSGRQSAQLGRSNDYLLEQYGLIWIVTDYEATIHRLPHFQETITIETKALSYNKFFCYRQFYIYDQEGGLLVDILAYFALLNPDTRKVATIPEDLVAPFETDFVKKLHRVPKMPLLEQSIDRDYYVRYFDIDMNGHVNNSKYLDWMYDVLGCEFLKTHQPLKMTLKYVKEVSPGGQITSSYHLDQLTSYHQITSDGQLNAQAMIEWRAIKQTESEID
>NC_012891.1|WP_012767110.1|1183500_1184631_-|oxygen-independent-coproporphyrinogen-III-oxidase
MSKKPTSAYVHIPFCTQICYYCDFSKVFIQNQPVDAYLEALIQEFESYDIHDLKTLYIGGGTPTAITADQLEYLLSHLERNLNLDDLEEFTIEANPGDLTPDKIEVLEHSAVNRISLGVQTFNNKQLKQIGRSHNEEQIYSTIANLKTAGFHNISIDLIYALPGQTLAQVKENVAKALALDIPHLSLYSLILEHHTVFMNKMRRGKLNLPTEDLEAEMFEYIISEMEANGFEHYEISNFTKPGFESRHNLMYWDNVEYFGCGAGASGYLNGIRYQNRVPIQHYLKAVEAGNARLNEEVLRKEEMMEEELFLGLRKKTGVSIQRFQEKFDISFEERYGTIVRDLQDQGLLVKDDAFVRMTKKGLFLGDSVAERFILD
>NC_012891.1|WP_002984855.1|1184692_1185334_-|hypothetical-protein
MTKQQIEKLADLLPPFAAKLYLDMIPEFQEGYASYVYQTQKEDTQNRRIKQLTKSFARLLDTPSFYVMPLSVQVGKQLLRNEEIACHSLSSVEAIQAFEAAVEDEKEVLQLLRNGSRLALLVLEEANETVHMDLGILTKVEQKVISPAMLTAIEEYLLATTEGNALQLTVTVEQGAARTFYQAHGFHQKADDLVFKPTDGKLICQMVKDLFKA
>NC_012891.1|WP_003056620.1|1185457_1186813_-|phosphoglucosamine-mutase
MGKYFGTDGVRGEANVELTPELAFKLGRFGGYVLSQHETERPKVFVARDTRISGEMLESALIAGLLSVGIEVYKLGVLATPGVSYLVRTEKASAGVMISASHNPALDNGIKFFGNDGFKLADDQELEIEALLDAPKDTLPRPSAEGLGTLVDYPEGLRKYEKFLVTTGTDLSGMTVALDTANGAASVSARDVFLDLNAEIAVIGEKPNGLNINDGVGSTHPEQLQELVKETGADLGLAFDGDSDRLIAVDETGEIVDGDRIMFIIGKYLSEKGLLAHNTIVTTVMSNLGFHKALDKQGINKAITAVGDRYVVEEMRHSGYNLGGEQSGHVIIMDYNTTGDGQLTAIQLTKVMKETGKSLSELAAEVTIYPQKLVNIRVENSMKERAMEVPAIANIIAKMEDEMAGNGRILVRPSGTEPLLRVMAEAPTDAEVDYYVDTIADVVRTEIGCDN

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Crispr_ID: NC_012891_3

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_012891_3

1601511-1601673

Unclear

Consensus_repeat	Method
TTCAAATATGATTTTTCGTATATTAATATATAGTAAA	PILER-CR

2 spacers

cas3

The CRISPR arrays of NC_012891_3

>merge|NC_012891|3|1601511-1601673|PILER-CR
TTCTAATACGATTTTTCGTATATTGTTTTATTTTAAAAAGCTTTTGTTTCCTTAAGCTTGATTTTATTATATATGATTTTTCGTATATAGTCAACTATTTTTTCTGTTTTTTTGTATTTTTTTCTCTTGAAATATGATTTTTCGTATGTTAATATATAGTAGA

>NC_012891|3|3|1601511-1601673|PILER-CR
TTCTAATACGATTTTTCGTATATTGTTTTATTTTAAA	AAGCTTTTGTTTCCTTAAGCTTGATTTTATTAT
ATATGATTTTTCGTATATAGTCAACTATTTTTTCTGT	TTTTTTGTATTTTTTTCTCTTGAAATATGATTTTTCG
TATGTTAATATATAGTAGA

Protein	Signature genes	Signature genes Name	Protein_function
NC_012891.1\|WP_012767417.1\|1604581_1605358_+\|recombination-regulator-RecX	unknown	unknown	gnl\|CDD\|237619
NC_012891.1\|WP_003061431.1\|1605439_1605973_+\|DUF402-domain-containing-protein	unknown	unknown	gnl\|CDD\|184219
NC_012891.1\|WP_012767410.1\|1600907_1601159_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|225848
NC_012891.1\|WP_012767406.1\|1598964_1599747_-\|ATP-binding-protein	unknown	unknown	gnl\|CDD\|236153
NC_012891.1\|WP_012767413.1\|1602022_1602400_+\|ImmA/IrrE-family-metallo-endopeptidase	unknown	unknown	gnl\|CDD\|368753
NC_012891.1\|WP_012767412.1\|1601697_1602039_+\|helix-turn-helix-transcriptional-regulator	unknown	unknown	gnl\|CDD\|238045
NC_012891.1\|WP_041789110.1\|1603267_1604434_+\|tyrosine-type-recombinase/integrase	unknown	unknown	gnl\|CDD\|271175
NC_012891.1\|WP_012767404.1\|1598476_1598827_-\|hypothetical-protein	unknown	unknown	unknown
NC_012891.1\|WP_012767419.1\|1614406_1615072_-\|ComF-family-protein	unknown	unknown	gnl\|CDD\|223970
NC_012891.1\|WP_003061817.1\|1613778_1614327_-\|ribosome-associated-translation-inhibitor-RaiA	unknown	unknown	gnl\|CDD\|224461
NC_012891.1\|WP_012767408.1\|1600549_1600756_-\|hypothetical-protein	unknown	unknown	unknown
NC_012891.1\|WP_012767409.1\|1600736_1600877_-\|hypothetical-protein	unknown	unknown	unknown
NC_012891.1\|WP_012767403.1\|1598235_1598490_-\|hypothetical-protein	unknown	unknown	unknown
NC_012891.1\|WP_012767407.1\|1599733_1600549_-\|phage-replisome-organizer-N-terminal-domain-containing-protein	unknown	unknown	gnl\|CDD\|130775
NC_012891.1\|WP_012767414.1\|1602408_1603095_+\|hypothetical-protein	unknown	unknown	unknown
NC_012891.1\|WP_012767411.1\|1601288_1601501_-\|helix-turn-helix-transcriptional-regulator	unknown	unknown	gnl\|CDD\|238045
NC_012891.1\|WP_003059901.1\|1615043_1616369_-\|DEAD/DEAH-box-helicase	cas3	cd09639_cas3_CAS-I	gnl\|CDD\|226583
NC_012891.1\|WP_012767402.1\|1597732_1598215_-\|siphovirus-Gp157-family-protein	unknown	unknown	gnl\|CDD\|368503
NC_012891.1\|WP_012767401.1\|1597057_1597732_-\|ERF-family-protein	unknown	unknown	gnl\|CDD\|377346
NC_012891.1\|WP_003053435.1\|1606026_1606338_+\|DUF960-domain-containing-protein	unknown	unknown	gnl\|CDD\|368760

Protein	Function_ID	Function_description	E-value
NC_012891.1\|WP_012767417.1\|1604581_1605358_+\|recombination-regulator-RecX	gnl\|CDD\|237619	PRK14135, recX, recombination regulator RecX; Provisional.	3.16389e-110
NC_012891.1\|WP_003061431.1\|1605439_1605973_+\|DUF402-domain-containing-protein	gnl\|CDD\|184219	PRK13662, PRK13662, hypothetical protein; Provisional.	1.46475e-132
NC_012891.1\|WP_012767413.1\|1602022_1602400_+\|ImmA/IrrE-family-metallo-endopeptidase	gnl\|CDD\|368753	pfam06114, Peptidase_M78, IrrE N-terminal-like domain. This entry includes the catalytic domain of the protein ImmA, which is a metallopeptidase containing an HEXXH zinc-binding motif from peptidase family M78. ImmA is encoded on a conjugative transposon. Conjugating bacteria are able to transfer conjugative transposons that can, for example, confer resistance to antibiotics. The transposon is integrated into the chromosome, but during conjugation excises itself and then moves to the recipient bacterium and re-integrate into its chromosome. Typically a conjugative tranposon encodes only the proteins required for this activity and the proteins that regulate it. During exponential growth, the ICEBs1 transposon of Bacillus subtilis is inactivated by the immunity repressor protein ImmR, which is encoded by the transposon and represses the genes for excision and transfer. Cleavage of ImmR relaxes repression and allows transfer of the transposon. ImmA has been shown to be essential for the cleavage of ImmR. This domain is also found in in metalloprotease IrrE, a central regulator of DNA damage repair in Deinococcaceae, HTH-type transcriptional regulators RamB and PrpC.	7.25281e-10
NC_012891.1\|WP_012767412.1\|1601697_1602039_+\|helix-turn-helix-transcriptional-regulator	gnl\|CDD\|238045	cd00093, HTH_XRE, Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators.	0.000216198
NC_012891.1\|WP_012767410.1\|1600907_1601159_-\|hypothetical-protein	gnl\|CDD\|225848	COG3311, AlpA, Predicted transcriptional regulator [Transcription].	0.00104763
NC_012891.1\|WP_012767406.1\|1598964_1599747_-\|ATP-binding-protein	gnl\|CDD\|236153	PRK08116, PRK08116, hypothetical protein; Validated.	2.65427e-28
NC_012891.1\|WP_041789110.1\|1603267_1604434_+\|tyrosine-type-recombinase/integrase	gnl\|CDD\|271175	cd00397, DNA_BRE_C, DNA breaking-rejoining enzymes, C-terminal catalytic domain. The DNA breaking-rejoining enzyme superfamily includes type IB topoisomerases and tyrosine based site-specific recombinases (integrases) that share the same fold in their catalytic domain containing conserved active site residues. The best-studied members of this diverse superfamily include Human topoisomerase I, the bacteriophage lambda integrase, the bacteriophage P1 Cre recombinase, the yeast Flp recombinase, and the bacterial XerD/C recombinases. Their overall reaction mechanism is essentially identical and involves cleavage of a single strand of a DNA duplex by nucleophilic attack of a conserved tyrosine to give a 3' phosphotyrosyl protein-DNA adduct. In the second rejoining step, a terminal 5' hydroxyl attacks the covalent adduct to release the enzyme and generate duplex DNA. The enzymes differ in that topoisomerases cleave and then rejoin the same 5' and 3' termini, whereas a site-specific recombinase transfers a 5' hydroxyl generated by recombinase cleavage to a new 3' phosphate partner located in a different duplex region. Many DNA breaking-rejoining enzymes also have N-terminal domains, which show little sequence or structure similarity.	2.5436e-25
NC_012891.1\|WP_012767419.1\|1614406_1615072_-\|ComF-family-protein	gnl\|CDD\|223970	COG1040, ComFC, Predicted amidophosphoribosyltransferases [General function prediction only].	3.68848e-51
NC_012891.1\|WP_003061817.1\|1613778_1614327_-\|ribosome-associated-translation-inhibitor-RaiA	gnl\|CDD\|224461	COG1544, COG1544, Ribosome-associated protein Y (PSrp-1) [Translation, ribosomal structure and biogenesis].	2.5279e-37
NC_012891.1\|WP_012767407.1\|1599733_1600549_-\|phage-replisome-organizer-N-terminal-domain-containing-protein	gnl\|CDD\|130775	TIGR01714, hypothetical_phage_protein, phage replisome organizer, putative, N-terminal region. This model represents the N-terminal domain of a small family of phage proteins. The protein contains a region of low-complexity sequence that reflects DNA direct repeats able to function as an origin of phage replication. The region covered by this model is N-terminal to the low-complexity region. [Mobile and extrachromosomal element functions, Prophage functions].	1.5934e-44
NC_012891.1\|WP_003059901.1\|1615043_1616369_-\|DEAD/DEAH-box-helicase	gnl\|CDD\|226583	COG4098, comFA, Superfamily II DNA/RNA helicase required for DNA uptake (late competence protein) [DNA replication, recombination, and repair].	0
NC_012891.1\|WP_012767411.1\|1601288_1601501_-\|helix-turn-helix-transcriptional-regulator	gnl\|CDD\|238045	cd00093, HTH_XRE, Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators.	0.00208945
NC_012891.1\|WP_012767402.1\|1597732_1598215_-\|siphovirus-Gp157-family-protein	gnl\|CDD\|368503	pfam05565, Sipho_Gp157, Siphovirus Gp157. This family contains both viral and bacterial proteins which are related to the Gp157 protein of the Streptococcus thermophilus SFi bacteriophages. It is thought that bacteria possessing the gene coding for this protein have an increased resistance to the bacteriophage.	6.9424e-38
NC_012891.1\|WP_012767401.1\|1597057_1597732_-\|ERF-family-protein	gnl\|CDD\|377346	pfam04404, ERF, ERF superfamily. The DNA single-strand annealing proteins (SSAPs), such as RecT, Red-beta, ERF and Rad52, function in RecA-dependent and RecA-independent DNA recombination pathways. This family includes proteins related to ERF.	6.70788e-29
NC_012891.1\|WP_003053435.1\|1606026_1606338_+\|DUF960-domain-containing-protein	gnl\|CDD\|368760	pfam06124, DUF960, Staphylococcal protein of unknown function (DUF960). This family consists of several hypothetical proteins from several species of Staphylococcus. The function of this family is unknown.	2.63618e-38

>NC_012891.1|WP_012767411.1|1601288_1601501_-|helix-turn-helix-transcriptional-regulator
MKNIEYIRKEKGVSLVDIADCLHLKSQTVREKINGDSDFKFGEALKVQQTFFPEFDIIYLFKERKEISVV
>NC_012891.1|WP_012767410.1|1600907_1601159_-|hypothetical-protein
MDNILLSLSDWIKEIIEKTVNRLVQMKLDELNAELWTREKVAERLGMSPGTFDKYYRHDKNFPKELPGVRWKKAEIIAWLNNK
>NC_012891.1|WP_012767409.1|1600736_1600877_-|hypothetical-protein
MKLFNFIFAKPKKQEQIKHDTLRASSEKQWAEFDAYMRKQYGTTTN
>NC_012891.1|WP_012767408.1|1600549_1600756_-|hypothetical-protein
MEQQLIKDNEFLRDENTRLNKEFSELNHAVAKANLLDVIIEEGYILQSTLDKCIAKLDEIDRRELERG
>NC_012891.1|WP_012767407.1|1599733_1600549_-|phage-replisome-organizer-N-terminal-domain-containing-protein
MADNKKYYYLKLKENFFESDEAIILESMSDGYIYSNILLKLYLRSLKNDGLLMFNNLIPYNAQMLATITRHQVGTIEKAIQIFRDLQLIEILDNGAIYMTNIQNFVGKSSSQADYMRNYREKKVGLTNVNQNSYICEPEIEIEIEKDKKIDINIDIKTEVEEEIKDSSATADEKSNFNIFEYYQSRIGVLDGYQAEKLNAYIKIDKLESKLVKRAIDRAADNSKRSFGYVNSILKSWAQNGITTITQQDEEQRQFQSKNSKQEEVSEYDTW
>NC_012891.1|WP_012767406.1|1598964_1599747_-|ATP-binding-protein
MILGDEDAFAKIAISYQQNTKKEDTVCEKHGCRYITVLKTGLTVCPDCHREELENQNTLHVQKQYERELENKRLYYLKKLSIMDDELENASFDNFRAETSKHKEVLSWAKAMANDWFLGGKGNIIMTGKAGRGKSHLAYSIIRGLSDKTKKLGLLVNVTDLLSEIKRDFSKEAFWMDKLKDVDYLVLDDLGAEKVSDWSTSIIYSLLNKRTNTIITTNLTPAEIRKIYGERIASRIRKGCDKSHIMEFDGMNDERMKLWN
>NC_012891.1|WP_012767404.1|1598476_1598827_-|hypothetical-protein
MELLNHLTDLEKRVFCFIPMGAERKVSNEEIRKTFGLTDREVRQIVYDLIQKGVPVVASKQKDGGYYLPTTKMERQEGLRANKSQVRSEIKRIKAVESVDLIEFAKAASEVRNGRN
>NC_012891.1|WP_012767403.1|1598235_1598490_-|hypothetical-protein
MVEIRINEETITFDSNFRDAFIFTIDCLRGSEEPTLKQTYQEFKDYTDEDLMDYIETEFDVWPELVINRRIDSKWSTKQHILDD
>NC_012891.1|WP_012767402.1|1597732_1598215_-|siphovirus-Gp157-family-protein
MAYLYELEGIAAYLESLDLDDETFQNTLDSIDFQSDLENNIEYFVKMLKNVQADAEMYKAEKEAFYKKQKQAEAKAEKYKETIRRAMELSQKKKVDAGMFKVSLRRSKKIEILDETKIPLDYMQEKIEYKPMKSEISKALKSGIEVSGVELIETESLQVK
>NC_012891.1|WP_012767401.1|1597057_1597732_-|ERF-family-protein
MKKSESITEYAKAFCKAQLEVKQPLKDKDNPFFKSKYVPLENVTEAITKAFANNGISFSQDPTTNTENGYIDVATLVMHTSGEWVEYGPLSVKPTKNDVQGAGSAITYAKRYALSAIFGITSDQDDDGNEASKPNNPSQSPKATTKKTQKTGYQTPKISNIQVETYKSDLNDIAKTTNQNVEELTKWLTDTLKIKSLEDLHTEQIVSTDDLINKLKKRAGLKND
>NC_012891.1|WP_012767412.1|1601697_1602039_+|helix-turn-helix-transcriptional-regulator
MDEKDLKRIIESRYNSVRAFAIENDIPYTTMRSILERGVMNAKAETIFKICDALGINPESFAEEKSDWQSTIDLSNLRERVVMFDGKPLSDDDVKKIEAIIKLSLGVGNGEDK
>NC_012891.1|WP_012767413.1|1602022_1602400_+|ImmA/IrrE-family-metallo-endopeptidase
MVKINEILSQYNIKLFEFPDTMWDRSGFYYPDHRIIYVNKNLSEKDRKKVILHEIGHIEHDPKQYQRLLLKYENQADRFMVRELIKDYLSDHDIYSFDWLKFANYYKISTSWGQEMIQDEFRKLI
>NC_012891.1|WP_012767414.1|1602408_1603095_+|hypothetical-protein
MKIGLRTPSLKKSIKARTTGKIKRALKKTVNPVYGKKGVGLITDPKKAIYNKVYKKTTFGGLSGIDLNSSKNHSFLDLFKSPKKEKKSEVKRKEIELTNLVNECEHKLFLYNQSMTIVNDTTNPDTFFNNLDTAKYSLERAVEISKYDFINASGDDLEKGLERLTNEKLNIEEEFVKRYYFDNIKKANVLKTEKGKQNNLSKGKERLLEYRDKFEDDTIKLIDILYNN
>NC_012891.1|WP_041789110.1|1603267_1604434_+|tyrosine-type-recombinase/integrase
MKYNKTKYPNIFWYVTLKGKRYYIRRGYYLNGEKKEATESNIKTIREARLILAEIERKIENNEFAYNKNLTVDEYWEIYVDNRLKAGAWSPDTYVERTNIFKNHISSKFGNKKMNAINRIEYENYINNLLNTNSRSTVKHIYDVFSIMLNHAVKNKMLDDNIIKFIDIGDSEIKPINKRRSMQEFKAWDKIAREMLDDYDYAMVRITYLGLRRSEVAGIKLGNITFNDKDCAVVKIDESRTRGRKDGGSLKTAYSERYVYLDFETSQLLKKAIDTSIKIAVCNDRILNKADFLFLGDDEKVKPSFVGKPIGSHYIYCLFKKINKNCDVHFTPHMMRHFFATQGQIAGVPIEHMAAALGHSNNYMTSQYTHIKDEVGENVTAAFMGSIK
>NC_012891.1|WP_012767417.1|1604581_1605358_+|recombination-regulator-RecX
MKITKIEKKKRLYLVEFDDNDALYVTEDTVVHFMLSKDKVLDNDQLEDIKHFAQLSYGKNLALYFLSFQQRSQKQVKDYLLKHDIDESIIPDIIHHLQQDKWLDDAKLAETYIRQNQLNGDKGPQVLKQKLLQKGIASHDIDPILSQTDFNQLAQKVSQKLFSKYQGKLPPKALKDKLMQSLLTKGFSYDSAKHSLNQLNFDQDNQDIEDLLDKELDKQYRKLSRKYDGYTLKQKLYQTLYRKGYPSDDITSKLRDYL
>NC_012891.1|WP_003061431.1|1605439_1605973_+|DUF402-domain-containing-protein
MKLPKEGDFITIQSYKHDGRLHRTWRDTMVLKTTENALIGVNDHTLVTESDGRRWVTREPAIVYFHKKYWFNIIAMIRDNGVSYYCNLASPYMMDTEALKYIDYDLDVKVFADGEKRLLDVDEYEVHKKEMQYSADMDFILKENVKILVDWINHEKGPFSKAYISIWYKRYLELKNR
>NC_012891.1|WP_003053435.1|1606026_1606338_+|DUF960-domain-containing-protein
MAFQKAKERYASFGVATSLPPELIDTFWEIIDHYLKGVFPLNNLLVFKLIKNKQYLSYEYIDRKRGLRIVFDYKARFDPFYPRTIYVVDNSGIETILLPHEIN
>NC_012891.1|WP_003061817.1|1613778_1614327_-|ribosome-associated-translation-inhibitor-RaiA
MIKFSIRGENIEVTEAIRDYVESKLTKIEKYFVEEQEIDARVNLKVYREKSSKVEVTIPLGSVTLRAEDVSQDMYGSIDLVVDKIERQIRKNKTKIAKKHREKVPTGQVFTTEFEAEQVDETPEVKVVRTKNLTLKPMDVEEARLQMELLGHDFFIYTDAEDGETNILYRREDGDLGLIEAK
>NC_012891.1|WP_012767419.1|1614406_1615072_-|ComF-family-protein
MICLLCQQFSPLPLRITDILFLKPQTTTLCQECQQGFQKISFTSCQTCNAPSQSSPCSDCLEWKVKGYEVNHKSLYQYNAAMKAYFSQYKFQGDYLLRHVFAQELAQVIKKDYPDFTPVPVPISKERYEERHFNQVTAILEAGNINYCMLFKRMDTSRQSSKTKNERLLSKDAYRLSTLSELPAKILIIDDIYTTGSTIIALKKLLMHVGNSDIKSLSIAR
>NC_012891.1|WP_003059901.1|1615043_1616369_-|DEAD/DEAH-box-helicase
MEGIENSYGRLFLKHQLPKEVNHLAKTLESIVAIKGKVTCQRCHYQITAEARLPSGTYYCRFCLVFGRNQADRPLYYIPPHPFPIANYLQWKGILTPYQESISNQLVKNVHAKKPTLVHAVTGAGKTEMIYGAIAAVVNAGGWVCLASPRVDVCIELANRLKAAFSCRVTLLHADSEAYQRSPIIVATTHQLLTFYKAFDLLIIDEVDAFPFVNNHQLQYAAQQAAKEGASSIVLTATSTKELEEQVKSGELEKLTLARRFHGNPLILPKFIRSFGLLKKIHCQKLPRALVKSISQQRKTGCPLLIFLPIIAMAELVTELLKLAFPEEQIACVSSQSADRVKDIDAFRQGKKGILVTTTILERGVTFPGVDVFVLMAQHRGYSSQSLVQIAGRVGRSIERPTGKVYFFHDGISQAMRNARKEIKEMNQKGYLNDMPPMSTI

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Crispr_ID: NC_012891_4

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_012891_4

2067331-2067427

Orphan

Consensus_repeat	Method
AAAAACCCAATTTTTTTTCGTCTTAT	CRISPRCasFinder

1 spacers

The CRISPR arrays of NC_012891_4

>merge|NC_012891|4|2067331-2067427|CRISPRCasFinder
AAAAACCCAATTTTTTTTCGTCTTATTTTTGCAAAATCTATATTAACGCAAATAAATTTGGTTGCCAAGATAAAAATCCAATTTTTTTTCGTCTTAT

>NC_012891|4|3|2067331-2067427|CRISPRCasFinder
AAAAACCCAATTTTTTTTCGTCTTAT	TTTTGCAAAATCTATATTAACGCAAATAAATTTGGTTGCCAAGAT
AAAAATCCAATTTTTTTTCGTCTTAT

Protein	Signature genes	Signature genes Name	Protein_function
NC_012891.1\|WP_012767678.1\|2075946_2077845_-\|tRNA-uridine-5-carboxymethylaminomethyl(34)-synthesis-enzyme-MnmG	unknown	unknown	gnl\|CDD\|235362
NC_012891.1\|WP_002982092.1\|2070325_2070937_-\|30S-ribosomal-protein-S4	unknown	unknown	gnl\|CDD\|235411
NC_012891.1\|WP_012767671.1\|2066547_2067111_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|226144
NC_012891.1\|WP_012767667.1\|2064563_2065085_-\|hypothetical-protein	unknown	unknown	unknown
NC_012891.1\|WP_012767676.1\|2073430_2073883_-\|50S-ribosomal-protein-L9	unknown	unknown	gnl\|CDD\|234659
NC_012891.1\|WP_014612651.1\|2065371_2065569_-\|hypothetical-protein	unknown	unknown	unknown
NC_012891.1\|WP_012767669.1\|2065686_2066019_-\|hypothetical-protein	unknown	unknown	unknown
NC_012891.1\|WP_012767668.1\|2065094_2065463_-\|hypothetical-protein	unknown	unknown	unknown
NC_012891.1\|WP_012767677.1\|2073879_2075856_-\|DHH-family-phosphoesterase	unknown	unknown	gnl\|CDD\|226404
NC_012891.1\|WP_014612653.1\|2066242_2066485_-\|hypothetical-protein	unknown	unknown	unknown
NC_012891.1\|WP_003055134.1\|2071125_2071593_-\|helix-turn-helix-transcriptional-regulator	unknown	unknown	gnl\|CDD\|238045
NC_012891.1\|WP_011285321.1\|2067126_2067315_-\|helix-turn-helix-transcriptional-regulator	unknown	unknown	gnl\|CDD\|238045
NC_012891.1\|WP_012767672.1\|2067483_2067927_+\|helix-turn-helix-transcriptional-regulator	unknown	unknown	gnl\|CDD\|238045
NC_012891.1\|WP_014612652.1\|2065549_2065690_-\|hypothetical-protein	unknown	unknown	unknown
NC_012891.1\|WP_003045773.1\|2062500_2062674_-\|hypothetical-protein	unknown	unknown	unknown
NC_012891.1\|WP_003055136.1\|2071745_2072018_-\|Veg-family-protein	unknown	unknown	gnl\|CDD\|226872
NC_012891.1\|WP_012767673.1\|2068237_2068762_+\|hypothetical-protein	unknown	unknown	unknown
NC_012891.1\|WP_012767666.1\|2062960_2064574_-\|hypothetical-protein	unknown	unknown	unknown
NC_012891.1\|WP_012767674.1\|2069005_2070169_+\|site-specific-integrase	unknown	unknown	gnl\|CDD\|271189
NC_012891.1\|WP_041789162.1\|2072033_2073395_-\|replicative-DNA-helicase	unknown	unknown	gnl\|CDD\|180232

Protein	Function_ID	Function_description	E-value
NC_012891.1\|WP_011285321.1\|2067126_2067315_-\|helix-turn-helix-transcriptional-regulator	gnl\|CDD\|238045	cd00093, HTH_XRE, Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators.	0.00222954
NC_012891.1\|WP_012767672.1\|2067483_2067927_+\|helix-turn-helix-transcriptional-regulator	gnl\|CDD\|238045	cd00093, HTH_XRE, Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators.	6.56289e-06
NC_012891.1\|WP_002982092.1\|2070325_2070937_-\|30S-ribosomal-protein-S4	gnl\|CDD\|235411	PRK05327, rpsD, 30S ribosomal protein S4; Validated.	8.00838e-118
NC_012891.1\|WP_012767671.1\|2066547_2067111_-\|hypothetical-protein	gnl\|CDD\|226144	COG3617, COG3617, Prophage antirepressor [Transcription].	2.45933e-25
NC_012891.1\|WP_041789162.1\|2072033_2073395_-\|replicative-DNA-helicase	gnl\|CDD\|180232	PRK05748, PRK05748, replicative DNA helicase; Provisional.	0
NC_012891.1\|WP_012767678.1\|2075946_2077845_-\|tRNA-uridine-5-carboxymethylaminomethyl(34)-synthesis-enzyme-MnmG	gnl\|CDD\|235362	PRK05192, PRK05192, tRNA uridine-5-carboxymethylaminomethyl(34) synthesis enzyme MnmG.	0
NC_012891.1\|WP_003055136.1\|2071745_2072018_-\|Veg-family-protein	gnl\|CDD\|226872	COG4466, Veg, Uncharacterized protein conserved in bacteria [Function unknown].	3.00913e-32
NC_012891.1\|WP_012767674.1\|2069005_2070169_+\|site-specific-integrase	gnl\|CDD\|271189	cd01189, INT_ICEBs1_C_like, C-terminal catalytic domain of integrases from bacterial phages and conjugate transposons. This family of tyrosine based site-specific integrases is has origins in bacterial phages and conjugate transposons. One member is the integrase from Bacillus subtilis conjugative transposon ICEBs1. ICEBs1 can be excised and transfered to various recipients in response to DNA damage or high concentrations of potential mating partners. The family belongs to the superfamily of DNA breaking-rejoining enzymes, which share the same fold in their catalytic domain and the overall reaction mechanism. The catalytic domain contains six conserved active site residues. Their overall reaction mechanism involves cleavage of a single strand of a DNA duplex by nucleophilic attack of a conserved tyrosine to give a 3' phosphotyrosyl protein-DNA adduct. In the second rejoining step, a terminal 5' hydroxyl attacks the covalent adduct to release the enzyme and generate duplex DNA.	8.65124e-46
NC_012891.1\|WP_012767676.1\|2073430_2073883_-\|50S-ribosomal-protein-L9	gnl\|CDD\|234659	PRK00137, rplI, 50S ribosomal protein L9; Reviewed.	2.30533e-54
NC_012891.1\|WP_012767677.1\|2073879_2075856_-\|DHH-family-phosphoesterase	gnl\|CDD\|226404	COG3887, COG3887, Predicted signaling protein consisting of a modified GGDEF domain and a DHH domain [Signal transduction mechanisms].	0
NC_012891.1\|WP_003055134.1\|2071125_2071593_-\|helix-turn-helix-transcriptional-regulator	gnl\|CDD\|238045	cd00093, HTH_XRE, Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators.	5.57805e-13

>NC_012891.1|WP_011285321.1|2067126_2067315_-|helix-turn-helix-transcriptional-regulator
MLITENIAVKVRKKRAVKQLGKVELSKKLGITPPTLSKIEAGNYKAPKRIYASVMEWLAEDY
>NC_012891.1|WP_012767671.1|2066547_2067111_-|hypothetical-protein
MNKQVSIFEEVNGNMRQVMQVIATTDFQGHQLDIYGDIQEPLFMARDVAEMIDYSQTTQGKWNVAKMISLVDEDEKLKGIPNGNTLINSGTKVWFLTEHGLYEVLMRSSKPKAKEFKKAVKNILKEIRLNGYYMQGELIQNSQPTPDIDDLSYVKQKLTDLQNVDSLQDLRWKMAKLYHVIETLDEY
>NC_012891.1|WP_014612653.1|2066242_2066485_-|hypothetical-protein
MKATTYKELKKWINEGVDLAELAQAYADKVPSVDREQFEAVTQEIFNVLEGVSLMLDDKVLIYNRKAEQKRLNDIEQGDY
>NC_012891.1|WP_012767669.1|2065686_2066019_-|hypothetical-protein
MKYRVETNPFSKDRYTPEQLEMFKNRQLSKDKAEAYFTRLYNQHIAWVIIANVMTEYVNKFRKSATSFEEAWEALGYQRTTEIVFRAVNGLPCSEKDTGELETYLSEVSA
>NC_012891.1|WP_014612652.1|2065549_2065690_-|hypothetical-protein
MRSIEELKAIAEYILEHMTDSEKAHFPNMTREEIKGLIIKYDSSRT
>NC_012891.1|WP_014612651.1|2065371_2065569_-|hypothetical-protein
MTVQELNLTPTQTLVLFIVLGLVGLLLSLSKPLIEIDLPEDTQVPKPRQNANYGAYIQSQNHYYN
>NC_012891.1|WP_012767668.1|2065094_2065463_-|hypothetical-protein
MTYQKIPKYLNHGRTQTMELIFNHRTIITIRREQMQLLSREAELELLEKVGCYLEKRWQLELENKDDWDLIPRQDLLEKLDITGTTLKNWEKEGLKSYQSPFENSKKVYYRKSDIYNFLSVD
>NC_012891.1|WP_012767667.1|2064563_2065085_-|hypothetical-protein
MDYLEVTMTKDCVKIFNFLYKYPTKAYQKDEYFKLLYMHPLDSFLTSFSLSGIRVKVTDKPVLAGWKLVRDIEVRIATGELLEMIEELEICYLRKHQTVSYVEIKFYVVYLLTYGIRSRYDMQFFTKLLFCCGYDQETVISIYSNITKNTRLSRDFITLQAKLYQTKKGTHEH
>NC_012891.1|WP_012767666.1|2062960_2064574_-|hypothetical-protein
MSIKENIDKLVSMEWTESIFGQSKMKADYKRQLSKVIELDTLSNIHHNGETYAVSNQEVMYLSESKGRTHKFISGNVKTKSKGKGRDSQKYLVVSFDHQFPPFAKLVVDYLLGRFTFFNNKLYDVNNRQAQVLDDFTIQSLYGFKKDNPFILEILEGIHQTLNIRPAKQLEAYKISGRDFIIDLKEHRLYRTNPSPDSSFFKFYDVDYHAAIGSKKKVGKFLGYVIADHDSLHNATLQAYYIAQVACGLKSKQNFFISKSGVRTGKGLRHIGLSGIFNKIDVELDLLIKGGFEASNAWGAFAGGEMALATEQGDIVGDKMERVLKIIATEKTHMARSIGGNLGTVNLTSVLCIDTNRTVALSDEMNGRAVLIQYQNRPEGETDLEREKAFEEYWQTFTEMDKSPKIEGVIGFLLVSLDYFRKNDMKFDWRAVEVVNDDDLDDFQVYLINHLSEKDFVERDSYVRELYNSTYGKNNNQAGQRMRTIGVKSYRKQTTGGRKIPGYKVDNIKRFNKFSGGEKENTNIFDMFEKLNQPPPP
>NC_012891.1|WP_003045773.1|2062500_2062674_-|hypothetical-protein
MKIKLFYQKHNESLDDFEYRVNQFTLSVSVIDIKFSEATYGNYEDMSTTTSLLVLYR
>NC_012891.1|WP_012767672.1|2067483_2067927_+|helix-turn-helix-transcriptional-regulator
MENRLQKIRKEQTNLNQKDFFDQVVNKKLNLDISFRTYQNWENPKNTIKPDKAQILADYFGVWLPYLLGNSNIRTEEQANFLAEMNKRINSEGDSFFFDMTVTESDEHDLLYNYRQLETPYKNQVRKFTRDMWELQKESKNFSPKSP
>NC_012891.1|WP_012767673.1|2068237_2068762_+|hypothetical-protein
MKKLVTLGATVLSILFLVACSNNSQPKTATKQTTTKEVVTNKTENKTPKNQKYKIGDKLTFNNGLEITVTNAEFTDERNEFDETNPEKVLKVTYNVVNNTDKEYLVSSEMELYVGNKKMETYPITSTTETLSSGRSYENAVTGFGVNGNEKMELEVKPTFSMSNEKFVVELDLQ
>NC_012891.1|WP_012767674.1|2069005_2070169_+|site-specific-integrase
MNIKEYKKKNGTIVYRTSVYLGVDQVTGKKARTTITASTKKGVKIKARDALNNFAMNGYTVKEKPTVTTYKELTALWWESYKNTIKPNSRQSMEGIVRLHILPAFGDCKLSRLTTPVIQQQVNKWANNANKGIKGAYANYSFLNNINRRILQYGVTMQVIEHNPARDVIIPRKQNNKEHKVKFFSNQELKQFLNYLDDLDLSSYENFFDYVLYKTLLATGCRIGEVLALEWSDIDLEKGTIKVSKTLNRYQETNTPKSKAGLRDIEIDRATVLLLKQYKNRQQVLSWDLGRSETIVFTPFTTKYAYACLLRKRLQKHFKAAGVPDISFHGFRHTHATIMLYAGIEAKDLQYRLGHSNISMTLNTYVHATKEGAKKAVSIFETAISNL
>NC_012891.1|WP_002982092.1|2070325_2070937_-|30S-ribosomal-protein-S4
MSRYTGPSWKQSRRLGLSLTGTGKELARRNYVPGQHGPNNRSKLSEYGLQLAEKQKLRFSYGLGEKQFRNLFVQATKIKEGTLGFNFMVLLERRLDNVVYRLGLATTRRQARQFVNHGHILVDGKRVDIPSYRVDPGQVISVREKSMKVPAILEAVEATLGRPAFVSFDAEKLEGSLTRLPERDEINPEINEALVVEFYNKML
>NC_012891.1|WP_003055134.1|2071125_2071593_-|helix-turn-helix-transcriptional-regulator
MDKQTILALKLKDYRDKNGLTQAQLAEQLEVSDKTISKWENGETYPSKRNMLAISEKLHFSLEALMIEETQVKTDYRKLSFKYTFYAYLAIFFVSMLILSSRYAANSLGDYNIEERLRAVLDMSLRSNCYAIPAAICIGLVFYYYIFPKQNVEDE
>NC_012891.1|WP_003055136.1|2071745_2072018_-|Veg-family-protein
MSDAFADVAKMKKIKEDIKAHEGQLVELTLENGRKREKNKIGRLIEVYSSLFIIEYNDSSDVPGAINNSYVESYTYSDILTEKTLIRYLD
>NC_012891.1|WP_041789162.1|2072033_2073395_-|replicative-DNA-helicase
MPEVAELRVQPQDLLAEQSVLGSIFISPDKLITVREFISPDDFYKYAHKIIFRAMITLSDRNDAIDATTVRTILDNQGDLQNIGGLSYIVELVNSVPTSANADYYAKIVAEKAMLRDIIARLTDTVNLAYEGASDSEDIIAGAERALIEINEHSNRSGFRKISDVLKVNYENLEARSKQTSDVTGLPTGFRDLDKITTGLHPDQLIILAARPAVGKTAFVLNIAQNVGTKQKRAVAIFSLEMGAESLVDRMLAAEGMVDSHSLRTGQLTDQDWNNVTIAQGALAEAPIYIDDTPGIKITEIRARSRKLSQEVDGGLGLIVIDYLQLITGTKPENRQQEVSDISRQLKILAKELKVPVIALSQLSRGVEQRQDKRPVLSDIRESGSIEQDADIVAFLYRDDYYRKEGEEAEEAIEDNTIEVILEKNRAGARGTVKLMFQKEYNKFSTIAQFEER
>NC_012891.1|WP_012767676.1|2073430_2073883_-|50S-ribosomal-protein-L9
MKVIFLADVKGKGKKGEIKEVPTGYAQNFLIKKNLAKEATSQSIGELKGKQKAEEKAQAEILAETQAIKAILDEDKTRVQFQEKVGPDGRTFGSITAKKISEELQKQFGVKVDKRHIILDHPIRAIGLVEVPVKLHKEVTAEIKLTITEA
>NC_012891.1|WP_012767677.1|2073879_2075856_-|DHH-family-phosphoesterase
MKRFRFETIHLIMMGLILFGLLALCVRIMQSKMLILSAIFLVLLFVVALLWYQKEVYELSDLDHIELLNEQTEDNLKTLLDKMPVGVVQFDQETNAVEWYNPYAELIFTTEDGLLQNHLIQQILTEKRRGDISQTFEVSGNKYTSYIDVASGIFYFFDSFVGNRQSADASMLRPVVGIISVDNYDDLTDDLSDADTSKINSFVANFIDEFMESKQIFYRRVNMDRYYFFTDFKTLKALMDDKFSVLEEFRKEAQEAQRPLTLSIGISFGEEKHSQIGQVALENLNIALVRGGDQIVIRENADHTNPIYFGGGSVSTVKRSRTRTRAMMTAISDRIKMVDNVFIVGHRKLDMDALGSAVGMQFFASNIIENSFAVYNPDEMSSDIERAIERLQADGKTRLISISQAMGLVTPRSLLVMVDHSKISLTLSKEFYEQFEDVIVVDHHRRDDDFPDNAILTFIESGASSAAELVTELIQFQNARKRLNKIQSSVLMAGIMLDTKNFSTRVTSRTFDVASYLRSKGSDSVEIQTISATDFDEYKQVNEIILQGQRLGDSIIVAAGENGKLYSNVIASKAADTILSMAHVEASFVLVETESHKIAISARSRSKINVQRVMEKLGGGGHFNLAACQLTDISLPQAKALLLETIDSTMKETGEVES
>NC_012891.1|WP_012767678.1|2075946_2077845_-|tRNA-uridine-5-carboxymethylaminomethyl(34)-synthesis-enzyme-MnmG
MTHEFTESYDVIVIGAGHAGVEASLATSRMGCKTLLATINLDMLAFMPCNPSIGGSAKGIVVREIDALGGEMGKNIDKTYIQMKMLNTGKGPAVRALRAQADKSLYAREMKHTVEKQANLTLRQTMIDDILVEDGRVVGVLTATGQKFAAKTVVVTTGTALRGEIILGELKYSSGPNNSLASVTLADNLKKLGLEIGRFKTGTPPRVKASSIDYDQTEIQPGDDKPNHFSFMSKDADYLKDQIPCWLTYTNQTSHDIINQNLYRAPMFSGIVKGVGPRYCPSIEDKIVRFADKERHQLFLEPEGRDTEEVYVQGLSTSLPEDVQKELIHSIKGLEKAEMMRTGYAIEYDIVLPHQLRATLETKLISGLFTAGQTNGTSGYEEAAGQGIIAGINAALKVQGKPELILKRSDAYIGVMIDDLVTKGTLEPYRLLTSRAEYRLILRHDNADMRLTEIGRDIGLVDDDRWNAFEIKKNQFDNELKRLDSIKLKPIKETNDRVQDLGFKPLTDAMTAKEFMRRPEIDYATAVSFVGPAAEDLDAKIIELLETEIKYEGYIRKALDQVAKMKRMEEKRIPANIDWDAIDSIATEARQKFKKINPETIGQASRISGVNPADISILMVYLEGNGKARRKS

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity
NC_012891_2	2.7\|1174000\|32\|NC_012891\|CRISPRCasFinder,CRT,PILER-CR	1174000-1174031	32	NC_012891.1	1596359-1596390	0	1.0
NC_012891_2	2.17\|1174662\|30\|NC_012891\|CRISPRCasFinder,CRT,PILER-CR	1174662-1174691	30	NC_012891.1	1751196-1751225	0	1.0

1. spacer 2.7|1174000|32|NC_012891|CRISPRCasFinder,CRT,PILER-CR matches to position: 1596359-1596390, mismatch: 0, identity: 1.0

acgctttagcagatggagcggggcttacgagg	CRISPR spacer
acgctttagcagatggagcggggcttacgagg	Protospacer
********************************

2. spacer 2.17|1174662|30|NC_012891|CRISPRCasFinder,CRT,PILER-CR matches to position: 1751196-1751225, mismatch: 0, identity: 1.0

cagacttggaattggccaatgagcgtgccg	CRISPR spacer
cagacttggaattggccaatgagcgtgccg	Protospacer
******************************

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NC_012891_2	2.1\|1173604\|30\|NC_012891\|CRISPRCasFinder,CRT	1173604-1173633	30	MK448681	Streptococcus phage Javan141, complete genome	39295-39324	0	1.0
NC_012891_2	2.1\|1173604\|30\|NC_012891\|CRISPRCasFinder,CRT	1173604-1173633	30	MK448690	Streptococcus phage Javan169, complete genome	43082-43111	0	1.0
NC_012891_2	2.1\|1173604\|30\|NC_012891\|CRISPRCasFinder,CRT	1173604-1173633	30	MK448856	Streptococcus phage Javan158, complete genome	18374-18403	0	1.0
NC_012891_2	2.4\|1173802\|30\|NC_012891\|CRISPRCasFinder,CRT,PILER-CR	1173802-1173831	30	MK448769	Streptococcus phage Javan471, complete genome	26865-26894	0	1.0
NC_012891_2	2.4\|1173802\|30\|NC_012891\|CRISPRCasFinder,CRT,PILER-CR	1173802-1173831	30	MK448684	Streptococcus phage Javan151, complete genome	26865-26894	0	1.0
NC_012891_2	2.4\|1173802\|30\|NC_012891\|CRISPRCasFinder,CRT,PILER-CR	1173802-1173831	30	MK448679	Streptococcus phage Javan137, complete genome	29407-29436	0	1.0
NC_012891_2	2.5\|1173868\|30\|NC_012891\|CRISPRCasFinder,CRT,PILER-CR	1173868-1173897	30	MK448834	Streptococcus phage Javan91, complete genome	29641-29670	0	1.0
NC_012891_2	2.5\|1173868\|30\|NC_012891\|CRISPRCasFinder,CRT,PILER-CR	1173868-1173897	30	KT388093	Streptococcus phage A25, complete genome	25659-25688	0	1.0
NC_012891_2	2.5\|1173868\|30\|NC_012891\|CRISPRCasFinder,CRT,PILER-CR	1173868-1173897	30	MK449009	Streptococcus phage Javan88, complete genome	31345-31374	0	1.0
NC_012891_2	2.5\|1173868\|30\|NC_012891\|CRISPRCasFinder,CRT,PILER-CR	1173868-1173897	30	KY349816	Streptococcus phage Str01, complete genome	13700-13729	0	1.0
NC_012891_2	2.6\|1173934\|30\|NC_012891\|CRISPRCasFinder,CRT,PILER-CR	1173934-1173963	30	MK448848	Streptococcus phage Javan126, complete genome	34238-34267	0	1.0
NC_012891_2	2.6\|1173934\|30\|NC_012891\|CRISPRCasFinder,CRT,PILER-CR	1173934-1173963	30	MK448857	Streptococcus phage Javan164, complete genome	34238-34267	0	1.0
NC_012891_2	2.6\|1173934\|30\|NC_012891\|CRISPRCasFinder,CRT,PILER-CR	1173934-1173963	30	MK448677	Streptococcus phage Javan133, complete genome	35238-35267	0	1.0
NC_012891_2	2.6\|1173934\|30\|NC_012891\|CRISPRCasFinder,CRT,PILER-CR	1173934-1173963	30	NC_009018	Streptococcus phage phi3396, complete genome	35487-35516	0	1.0
NC_012891_2	2.6\|1173934\|30\|NC_012891\|CRISPRCasFinder,CRT,PILER-CR	1173934-1173963	30	MK448682	Streptococcus phage Javan143, complete genome	37329-37358	0	1.0
NC_012891_2	2.6\|1173934\|30\|NC_012891\|CRISPRCasFinder,CRT,PILER-CR	1173934-1173963	30	MK448854	Streptococcus phage Javan146, complete genome	40069-40098	0	1.0
NC_012891_2	2.6\|1173934\|30\|NC_012891\|CRISPRCasFinder,CRT,PILER-CR	1173934-1173963	30	MK448680	Streptococcus phage Javan139, complete genome	34762-34791	0	1.0
NC_012891_2	2.8\|1174068\|30\|NC_012891\|CRISPRCasFinder,CRT	1174068-1174097	30	MK448690	Streptococcus phage Javan169, complete genome	41759-41788	0	1.0
NC_012891_2	2.10\|1174200\|30\|NC_012891\|CRISPRCasFinder,CRT	1174200-1174229	30	MK448769	Streptococcus phage Javan471, complete genome	14382-14411	0	1.0
NC_012891_2	2.10\|1174200\|30\|NC_012891\|CRISPRCasFinder,CRT	1174200-1174229	30	MK448684	Streptococcus phage Javan151, complete genome	14382-14411	0	1.0
NC_012891_2	2.10\|1174200\|30\|NC_012891\|CRISPRCasFinder,CRT	1174200-1174229	30	MK448680	Streptococcus phage Javan139, complete genome	15962-15991	0	1.0
NC_012891_2	2.11\|1174266\|30\|NC_012891\|CRISPRCasFinder,CRT	1174266-1174295	30	MK448848	Streptococcus phage Javan126, complete genome	10450-10479	0	1.0
NC_012891_2	2.11\|1174266\|30\|NC_012891\|CRISPRCasFinder,CRT	1174266-1174295	30	MK448857	Streptococcus phage Javan164, complete genome	10450-10479	0	1.0
NC_012891_2	2.11\|1174266\|30\|NC_012891\|CRISPRCasFinder,CRT	1174266-1174295	30	MK448677	Streptococcus phage Javan133, complete genome	11442-11471	0	1.0
NC_012891_2	2.13\|1174398\|30\|NC_012891\|CRISPRCasFinder,CRT	1174398-1174427	30	MK448792	Streptococcus phage Javan521, complete genome	22320-22349	0	1.0
NC_012891_2	2.13\|1174398\|30\|NC_012891\|CRISPRCasFinder,CRT	1174398-1174427	30	NC_009018	Streptococcus phage phi3396, complete genome	19987-20016	0	1.0
NC_012891_2	2.13\|1174398\|30\|NC_012891\|CRISPRCasFinder,CRT	1174398-1174427	30	MK448679	Streptococcus phage Javan137, complete genome	20334-20363	0	1.0
NC_012891_2	2.13\|1174398\|30\|NC_012891\|CRISPRCasFinder,CRT	1174398-1174427	30	MK448682	Streptococcus phage Javan143, complete genome	21996-22025	0	1.0
NC_012891_2	2.13\|1174398\|30\|NC_012891\|CRISPRCasFinder,CRT	1174398-1174427	30	MK448770	Streptococcus phage Javan477, complete genome	22320-22349	0	1.0
NC_012891_2	2.16\|1174596\|30\|NC_012891\|CRISPRCasFinder,CRT,PILER-CR	1174596-1174625	30	KT388093	Streptococcus phage A25, complete genome	28129-28158	0	1.0
NC_012891_2	2.16\|1174596\|30\|NC_012891\|CRISPRCasFinder,CRT,PILER-CR	1174596-1174625	30	KY349816	Streptococcus phage Str01, complete genome	16170-16199	0	1.0
NC_012891_2	2.18\|1174728\|30\|NC_012891\|CRISPRCasFinder,CRT,PILER-CR	1174728-1174757	30	MK449010	Streptococcus phage Javan90, complete genome	431-460	0	1.0
NC_012891_2	2.18\|1174728\|30\|NC_012891\|CRISPRCasFinder,CRT,PILER-CR	1174728-1174757	30	MK448681	Streptococcus phage Javan141, complete genome	431-460	0	1.0
NC_012891_2	2.18\|1174728\|30\|NC_012891\|CRISPRCasFinder,CRT,PILER-CR	1174728-1174757	30	MK448833	Streptococcus phage Javan87, complete genome	431-460	0	1.0
NC_012891_2	2.18\|1174728\|30\|NC_012891\|CRISPRCasFinder,CRT,PILER-CR	1174728-1174757	30	MK448856	Streptococcus phage Javan158, complete genome	431-460	0	1.0
NC_012891_3	3.1\|1601548\|33\|NC_012891\|PILER-CR	1601548-1601580	33	MK448681	Streptococcus phage Javan141, complete genome	2854-2886	0	1.0
NC_012891_4	4.1\|2067357\|45\|NC_012891\|CRISPRCasFinder	2067357-2067401	45	MK448333	Streptococcus satellite phage Javan145, complete genome	2769-2813	0	1.0
NC_012891_4	4.1\|2067357\|45\|NC_012891\|CRISPRCasFinder	2067357-2067401	45	MK448340	Streptococcus satellite phage Javan156, complete genome	2769-2813	0	1.0
NC_012891_2	2.4\|1173802\|30\|NC_012891\|CRISPRCasFinder,CRT,PILER-CR	1173802-1173831	30	MK448960	Streptococcus phage Javan492, complete genome	31506-31535	1	0.967
NC_012891_2	2.4\|1173802\|30\|NC_012891\|CRISPRCasFinder,CRT,PILER-CR	1173802-1173831	30	MK448973	Streptococcus phage Javan522, complete genome	32918-32947	1	0.967
NC_012891_2	2.4\|1173802\|30\|NC_012891\|CRISPRCasFinder,CRT,PILER-CR	1173802-1173831	30	MK448762	Streptococcus phage Javan447, complete genome	31638-31667	1	0.967
NC_012891_2	2.4\|1173802\|30\|NC_012891\|CRISPRCasFinder,CRT,PILER-CR	1173802-1173831	30	MK448952	Streptococcus phage Javan472, complete genome	31902-31931	1	0.967
NC_012891_2	2.4\|1173802\|30\|NC_012891\|CRISPRCasFinder,CRT,PILER-CR	1173802-1173831	30	NC_004585	Streptococcus prophage 315.2, complete genome	32224-32253	1	0.967
NC_012891_2	2.4\|1173802\|30\|NC_012891\|CRISPRCasFinder,CRT,PILER-CR	1173802-1173831	30	MK448966	Streptococcus phage Javan508, complete genome	32079-32108	1	0.967
NC_012891_2	2.4\|1173802\|30\|NC_012891\|CRISPRCasFinder,CRT,PILER-CR	1173802-1173831	30	NC_009018	Streptococcus phage phi3396, complete genome	29056-29085	1	0.967
NC_012891_2	2.4\|1173802\|30\|NC_012891\|CRISPRCasFinder,CRT,PILER-CR	1173802-1173831	30	MK448959	Streptococcus phage Javan488, complete genome	32767-32796	1	0.967
NC_012891_2	2.4\|1173802\|30\|NC_012891\|CRISPRCasFinder,CRT,PILER-CR	1173802-1173831	30	NC_004587	Streptococcus prophage 315.4, complete genome	31345-31374	1	0.967
NC_012891_2	2.4\|1173802\|30\|NC_012891\|CRISPRCasFinder,CRT,PILER-CR	1173802-1173831	30	NC_003157	Streptococcus pyogenes strain NIH1 putative methionine sulfoxide reductase gene, complete cds; and integrated temperate phage PhiNIH1.1, complete genome	32615-32644	1	0.967
NC_012891_2	2.4\|1173802\|30\|NC_012891\|CRISPRCasFinder,CRT,PILER-CR	1173802-1173831	30	MK448682	Streptococcus phage Javan143, complete genome	31069-31098	1	0.967
NC_012891_2	2.4\|1173802\|30\|NC_012891\|CRISPRCasFinder,CRT,PILER-CR	1173802-1173831	30	MK448766	Streptococcus phage Javan465, complete genome	32296-32325	1	0.967
NC_012891_2	2.4\|1173802\|30\|NC_012891\|CRISPRCasFinder,CRT,PILER-CR	1173802-1173831	30	MK448778	Streptococcus phage Javan493, complete genome	32558-32587	1	0.967
NC_012891_2	2.4\|1173802\|30\|NC_012891\|CRISPRCasFinder,CRT,PILER-CR	1173802-1173831	30	MK448977	Streptococcus phage Javan530, complete genome	31250-31279	1	0.967
NC_012891_2	2.4\|1173802\|30\|NC_012891\|CRISPRCasFinder,CRT,PILER-CR	1173802-1173831	30	MK448680	Streptococcus phage Javan139, complete genome	28496-28525	1	0.967
NC_012891_2	2.4\|1173802\|30\|NC_012891\|CRISPRCasFinder,CRT,PILER-CR	1173802-1173831	30	MK448845	Streptococcus phage Javan118, complete genome	27435-27464	1	0.967
NC_012891_2	2.4\|1173802\|30\|NC_012891\|CRISPRCasFinder,CRT,PILER-CR	1173802-1173831	30	MK448788	Streptococcus phage Javan511, complete genome	31250-31279	1	0.967
NC_012891_2	2.4\|1173802\|30\|NC_012891\|CRISPRCasFinder,CRT,PILER-CR	1173802-1173831	30	MK448950	Streptococcus phage Javan464, complete genome	31983-32012	1	0.967
NC_012891_2	2.4\|1173802\|30\|NC_012891\|CRISPRCasFinder,CRT,PILER-CR	1173802-1173831	30	MK448957	Streptococcus phage Javan484, complete genome	36734-36763	1	0.967
NC_012891_2	2.4\|1173802\|30\|NC_012891\|CRISPRCasFinder,CRT,PILER-CR	1173802-1173831	30	MK448975	Streptococcus phage Javan526, complete genome	33340-33369	1	0.967
NC_012891_2	2.4\|1173802\|30\|NC_012891\|CRISPRCasFinder,CRT,PILER-CR	1173802-1173831	30	MK448678	Streptococcus phage Javan135, complete genome	31098-31127	1	0.967
NC_012891_2	2.4\|1173802\|30\|NC_012891\|CRISPRCasFinder,CRT,PILER-CR	1173802-1173831	30	MK448782	Streptococcus phage Javan501, complete genome	35698-35727	1	0.967
NC_012891_2	2.4\|1173802\|30\|NC_012891\|CRISPRCasFinder,CRT,PILER-CR	1173802-1173831	30	MK448673	Streptococcus phage Javan119, complete genome	35790-35819	1	0.967
NC_012891_2	2.6\|1173934\|30\|NC_012891\|CRISPRCasFinder,CRT,PILER-CR	1173934-1173963	30	MK448769	Streptococcus phage Javan471, complete genome	32720-32749	1	0.967
NC_012891_2	2.6\|1173934\|30\|NC_012891\|CRISPRCasFinder,CRT,PILER-CR	1173934-1173963	30	MK448684	Streptococcus phage Javan151, complete genome	32720-32749	1	0.967
NC_012891_2	2.7\|1174000\|32\|NC_012891\|CRISPRCasFinder,CRT,PILER-CR	1174000-1174031	32	MK448685	Streptococcus phage Javan155, complete genome	8495-8526	1	0.969
NC_012891_2	2.7\|1174000\|32\|NC_012891\|CRISPRCasFinder,CRT,PILER-CR	1174000-1174031	32	MK448791	Streptococcus phage Javan517, complete genome	8973-9004	1	0.969
NC_012891_2	2.7\|1174000\|32\|NC_012891\|CRISPRCasFinder,CRT,PILER-CR	1174000-1174031	32	NC_004587	Streptococcus prophage 315.4, complete genome	9068-9099	1	0.969
NC_012891_2	2.7\|1174000\|32\|NC_012891\|CRISPRCasFinder,CRT,PILER-CR	1174000-1174031	32	MK448690	Streptococcus phage Javan169, complete genome	10403-10434	1	0.969
NC_012891_2	2.7\|1174000\|32\|NC_012891\|CRISPRCasFinder,CRT,PILER-CR	1174000-1174031	32	NC_003157	Streptococcus pyogenes strain NIH1 putative methionine sulfoxide reductase gene, complete cds; and integrated temperate phage PhiNIH1.1, complete genome	10338-10369	1	0.969
NC_012891_2	2.7\|1174000\|32\|NC_012891\|CRISPRCasFinder,CRT,PILER-CR	1174000-1174031	32	MK448977	Streptococcus phage Javan530, complete genome	8973-9004	1	0.969
NC_012891_2	2.7\|1174000\|32\|NC_012891\|CRISPRCasFinder,CRT,PILER-CR	1174000-1174031	32	MK448854	Streptococcus phage Javan146, complete genome	12316-12347	1	0.969
NC_012891_2	2.7\|1174000\|32\|NC_012891\|CRISPRCasFinder,CRT,PILER-CR	1174000-1174031	32	MK448788	Streptococcus phage Javan511, complete genome	8973-9004	1	0.969
NC_012891_2	2.7\|1174000\|32\|NC_012891\|CRISPRCasFinder,CRT,PILER-CR	1174000-1174031	32	MK448853	Streptococcus phage Javan144, complete genome	8495-8526	1	0.969
NC_012891_2	2.7\|1174000\|32\|NC_012891\|CRISPRCasFinder,CRT,PILER-CR	1174000-1174031	32	MK448683	Streptococcus phage Javan149, complete genome	12376-12407	1	0.969
NC_012891_2	2.10\|1174200\|30\|NC_012891\|CRISPRCasFinder,CRT	1174200-1174229	30	MK448698	Streptococcus phage Javan187, complete genome	14455-14484	1	0.967
NC_012891_2	2.10\|1174200\|30\|NC_012891\|CRISPRCasFinder,CRT	1174200-1174229	30	MK448895	Streptococcus phage Javan274, complete genome	15458-15487	1	0.967
NC_012891_2	2.13\|1174398\|30\|NC_012891\|CRISPRCasFinder,CRT	1174398-1174427	30	NC_004584	Streptococcus prophage 315.1, complete genome	21913-21942	1	0.967
NC_012891_2	2.13\|1174398\|30\|NC_012891\|CRISPRCasFinder,CRT	1174398-1174427	30	MK448978	Streptococcus phage Javan532, complete genome	21808-21837	1	0.967
NC_012891_2	2.13\|1174398\|30\|NC_012891\|CRISPRCasFinder,CRT	1174398-1174427	30	MK448785	Streptococcus phage Javan507, complete genome	21808-21837	1	0.967
NC_012891_3	3.2\|1601618\|37\|NC_012891\|PILER-CR	1601618-1601654	37	MK448681	Streptococcus phage Javan141, complete genome	2798-2834	1	0.973
NC_012891_4	4.1\|2067357\|45\|NC_012891\|CRISPRCasFinder	2067357-2067401	45	MK448522	Streptococcus satellite phage Javan519, complete genome	1870-1914	1	0.978
NC_012891_4	4.1\|2067357\|45\|NC_012891\|CRISPRCasFinder	2067357-2067401	45	MK448330	Streptococcus satellite phage Javan136, complete genome	2770-2814	1	0.978
NC_012891_4	4.1\|2067357\|45\|NC_012891\|CRISPRCasFinder	2067357-2067401	45	MK448328	Streptococcus satellite phage Javan130, complete genome	2770-2814	1	0.978
NC_012891_4	4.1\|2067357\|45\|NC_012891\|CRISPRCasFinder	2067357-2067401	45	MK448513	Streptococcus satellite phage Javan479, complete genome	1870-1914	1	0.978
NC_012891_4	4.1\|2067357\|45\|NC_012891\|CRISPRCasFinder	2067357-2067401	45	MK448332	Streptococcus satellite phage Javan142, complete genome	2777-2821	1	0.978
NC_012891_4	4.1\|2067357\|45\|NC_012891\|CRISPRCasFinder	2067357-2067401	45	MK448331	Streptococcus satellite phage Javan138, complete genome	2777-2821	1	0.978
NC_012891_2	2.4\|1173802\|30\|NC_012891\|CRISPRCasFinder,CRT,PILER-CR	1173802-1173831	30	MK448946	Streptococcus phage Javan456, complete genome	35811-35840	2	0.933
NC_012891_2	2.4\|1173802\|30\|NC_012891\|CRISPRCasFinder,CRT,PILER-CR	1173802-1173831	30	MK448775	Streptococcus phage Javan489, complete genome	34194-34223	2	0.933
NC_012891_2	2.4\|1173802\|30\|NC_012891\|CRISPRCasFinder,CRT,PILER-CR	1173802-1173831	30	MK448794	Streptococcus phage Javan525, complete genome	31317-31346	2	0.933
NC_012891_2	2.4\|1173802\|30\|NC_012891\|CRISPRCasFinder,CRT,PILER-CR	1173802-1173831	30	MK448955	Streptococcus phage Javan478, complete genome	34390-34419	2	0.933
NC_012891_2	2.4\|1173802\|30\|NC_012891\|CRISPRCasFinder,CRT,PILER-CR	1173802-1173831	30	MK448763	Streptococcus phage Javan451, complete genome	26895-26924	2	0.933
NC_012891_2	2.4\|1173802\|30\|NC_012891\|CRISPRCasFinder,CRT,PILER-CR	1173802-1173831	30	MK448953	Streptococcus phage Javan474, complete genome	35915-35944	2	0.933
NC_012891_2	2.4\|1173802\|30\|NC_012891\|CRISPRCasFinder,CRT,PILER-CR	1173802-1173831	30	MK448944	Streptococcus phage Javan452, complete genome	34963-34992	2	0.933
NC_012891_2	2.4\|1173802\|30\|NC_012891\|CRISPRCasFinder,CRT,PILER-CR	1173802-1173831	30	MK448772	Streptococcus phage Javan483, complete genome	32091-32120	2	0.933
NC_012891_2	2.4\|1173802\|30\|NC_012891\|CRISPRCasFinder,CRT,PILER-CR	1173802-1173831	30	MK448962	Streptococcus phage Javan496, complete genome	22550-22579	2	0.933
NC_012891_2	2.4\|1173802\|30\|NC_012891\|CRISPRCasFinder,CRT,PILER-CR	1173802-1173831	30	MK448958	Streptococcus phage Javan486, complete genome	31676-31705	2	0.933
NC_012891_2	2.4\|1173802\|30\|NC_012891\|CRISPRCasFinder,CRT,PILER-CR	1173802-1173831	30	MK448951	Streptococcus phage Javan470, complete genome	31580-31609	2	0.933
NC_012891_2	2.4\|1173802\|30\|NC_012891\|CRISPRCasFinder,CRT,PILER-CR	1173802-1173831	30	MK448793	Streptococcus phage Javan523, complete genome	32727-32756	2	0.933
NC_012891_2	2.4\|1173802\|30\|NC_012891\|CRISPRCasFinder,CRT,PILER-CR	1173802-1173831	30	MK448765	Streptococcus phage Javan459, complete genome	31315-31344	2	0.933
NC_012891_2	2.4\|1173802\|30\|NC_012891\|CRISPRCasFinder,CRT,PILER-CR	1173802-1173831	30	MK448954	Streptococcus phage Javan476, complete genome	31114-31143	2	0.933
NC_012891_2	2.6\|1173934\|30\|NC_012891\|CRISPRCasFinder,CRT,PILER-CR	1173934-1173963	30	MK448859	Streptococcus phage Javan170, complete genome	39727-39756	2	0.933
NC_012891_2	2.6\|1173934\|30\|NC_012891\|CRISPRCasFinder,CRT,PILER-CR	1173934-1173963	30	MK448688	Streptococcus phage Javan161, complete genome	39685-39714	2	0.933
NC_012891_2	2.6\|1173934\|30\|NC_012891\|CRISPRCasFinder,CRT,PILER-CR	1173934-1173963	30	MK448683	Streptococcus phage Javan149, complete genome	36707-36736	2	0.933
NC_012891_2	2.7\|1174000\|32\|NC_012891\|CRISPRCasFinder,CRT,PILER-CR	1174000-1174031	32	MK448795	Streptococcus phage Javan527, complete genome	15595-15626	2	0.938
NC_012891_2	2.7\|1174000\|32\|NC_012891\|CRISPRCasFinder,CRT,PILER-CR	1174000-1174031	32	NC_028700	Streptococcus phage T12, complete genome	9869-9900	2	0.938
NC_012891_2	2.7\|1174000\|32\|NC_012891\|CRISPRCasFinder,CRT,PILER-CR	1174000-1174031	32	MK448790	Streptococcus phage Javan515, complete genome	10325-10356	2	0.938
NC_012891_2	2.7\|1174000\|32\|NC_012891\|CRISPRCasFinder,CRT,PILER-CR	1174000-1174031	32	MK448793	Streptococcus phage Javan523, complete genome	10193-10224	2	0.938
NC_012891_2	2.7\|1174000\|32\|NC_012891\|CRISPRCasFinder,CRT,PILER-CR	1174000-1174031	32	MK448954	Streptococcus phage Javan476, complete genome	9993-10024	2	0.938
NC_012891_2	2.7\|1174000\|32\|NC_012891\|CRISPRCasFinder,CRT,PILER-CR	1174000-1174031	32	MK448950	Streptococcus phage Javan464, complete genome	9915-9946	2	0.938
NC_012891_2	2.9\|1174134\|30\|NC_012891\|CRISPRCasFinder,CRT	1174134-1174163	30	MK448775	Streptococcus phage Javan489, complete genome	10358-10387	2	0.933
NC_012891_2	2.9\|1174134\|30\|NC_012891\|CRISPRCasFinder,CRT	1174134-1174163	30	MK448794	Streptococcus phage Javan525, complete genome	8553-8582	2	0.933
NC_012891_2	2.9\|1174134\|30\|NC_012891\|CRISPRCasFinder,CRT	1174134-1174163	30	MK448763	Streptococcus phage Javan451, complete genome	7583-7612	2	0.933
NC_012891_2	2.9\|1174134\|30\|NC_012891\|CRISPRCasFinder,CRT	1174134-1174163	30	MK448765	Streptococcus phage Javan459, complete genome	8553-8582	2	0.933
NC_012891_2	2.13\|1174398\|30\|NC_012891\|CRISPRCasFinder,CRT	1174398-1174427	30	MK448860	Streptococcus phage Javan172, complete genome	21823-21852	2	0.933
NC_012891_2	2.1\|1173604\|30\|NC_012891\|CRISPRCasFinder,CRT	1173604-1173633	30	NC_009018	Streptococcus phage phi3396, complete genome	37420-37449	3	0.9
NC_012891_2	2.4\|1173802\|30\|NC_012891\|CRISPRCasFinder,CRT,PILER-CR	1173802-1173831	30	MK448852	Streptococcus phage Javan140, complete genome	31193-31222	3	0.9
NC_012891_2	2.10\|1174200\|30\|NC_012891\|CRISPRCasFinder,CRT	1174200-1174229	30	MK448818	Streptococcus phage Javan597, complete genome	20342-20371	3	0.9
NC_012891_2	2.4\|1173802\|30\|NC_012891\|CRISPRCasFinder,CRT,PILER-CR	1173802-1173831	30	MK448779	Streptococcus phage Javan497, complete genome	31151-31180	4	0.867
NC_012891_2	2.4\|1173802\|30\|NC_012891\|CRISPRCasFinder,CRT,PILER-CR	1173802-1173831	30	MK448968	Streptococcus phage Javan512, complete genome	31151-31180	4	0.867
NC_012891_2	2.4\|1173802\|30\|NC_012891\|CRISPRCasFinder,CRT,PILER-CR	1173802-1173831	30	MK448864	Streptococcus phage Javan180, complete genome	22077-22106	4	0.867
NC_012891_2	2.4\|1173802\|30\|NC_012891\|CRISPRCasFinder,CRT,PILER-CR	1173802-1173831	30	MK448797	Streptococcus phage Javan531, complete genome	31151-31180	4	0.867
NC_012891_2	2.4\|1173802\|30\|NC_012891\|CRISPRCasFinder,CRT,PILER-CR	1173802-1173831	30	NC_004589	Streptococcus prophage 315.6, complete genome	31248-31277	4	0.867
NC_012891_2	2.11\|1174266\|30\|NC_012891\|CRISPRCasFinder,CRT	1174266-1174295	30	NZ_CP036355	Bacillus sp. SYJ plasmid unnamed1, complete sequence	194049-194078	4	0.867
NC_012891_2	2.11\|1174266\|30\|NC_012891\|CRISPRCasFinder,CRT	1174266-1174295	30	CP008939	Candidatus Caedibacter acanthamoebae plasmid Plasmid_00003, complete sequence	27192-27221	4	0.867
NC_012891_2	2.4\|1173802\|30\|NC_012891\|CRISPRCasFinder,CRT,PILER-CR	1173802-1173831	30	MK448933	Streptococcus phage Javan420, complete genome	34909-34938	5	0.833
NC_012891_2	2.11\|1174266\|30\|NC_012891\|CRISPRCasFinder,CRT	1174266-1174295	30	NC_011412	Clostridium perfringens plasmid pCP8533etx, complete sequence	32356-32385	5	0.833
NC_012891_2	2.11\|1174266\|30\|NC_012891\|CRISPRCasFinder,CRT	1174266-1174295	30	LR588166	Pseudomonas phage vB_PaeM_MIJ3	197412-197441	5	0.833
NC_012891_2	2.3\|1173736\|30\|NC_012891\|CRISPRCasFinder,CRT,PILER-CR	1173736-1173765	30	MK448925	Streptococcus phage Javan386, complete genome	30665-30694	6	0.8
NC_012891_2	2.8\|1174068\|30\|NC_012891\|CRISPRCasFinder,CRT	1174068-1174097	30	MN693492	Marine virus AFVG_25M361, complete genome	3579-3608	6	0.8
NC_012891_2	2.11\|1174266\|30\|NC_012891\|CRISPRCasFinder,CRT	1174266-1174295	30	MT080586	UNVERIFIED: Staphylococcus phage vB_SauM_EW2, complete genome	91842-91871	6	0.8
NC_012891_2	2.11\|1174266\|30\|NC_012891\|CRISPRCasFinder,CRT	1174266-1174295	30	MT080594	UNVERIFIED: Staphylococcus phage vB_SauM_EW4, complete genome	6005-6034	6	0.8
NC_012891_2	2.11\|1174266\|30\|NC_012891\|CRISPRCasFinder,CRT	1174266-1174295	30	MT080582	UNVERIFIED: Staphylococcus phage vB_SauM_EW1, complete genome	23908-23937	6	0.8
NC_012891_2	2.11\|1174266\|30\|NC_012891\|CRISPRCasFinder,CRT	1174266-1174295	30	AP013721	Uncultured Mediterranean phage uvMED isolate uvMED-CGF-C22A-MedDCM-OCT-S45-C35, * SEQUENCING IN PROGRESS *	31134-31163	6	0.8
NC_012891_2	2.11\|1174266\|30\|NC_012891\|CRISPRCasFinder,CRT	1174266-1174295	30	AP014427	Uncultured Mediterranean phage uvMED isolate uvMED-CGF-C22-MedDCM-OCT-S28-C14, * SEQUENCING IN PROGRESS *, 3 ordered pieces	25972-26001	6	0.8
NC_012891_2	2.11\|1174266\|30\|NC_012891\|CRISPRCasFinder,CRT	1174266-1174295	30	MK448860	Streptococcus phage Javan172, complete genome	12441-12470	6	0.8
NC_012891_2	2.11\|1174266\|30\|NC_012891\|CRISPRCasFinder,CRT	1174266-1174295	30	NZ_CP036355	Bacillus sp. SYJ plasmid unnamed1, complete sequence	18476-18505	7	0.767
NC_012891_2	2.11\|1174266\|30\|NC_012891\|CRISPRCasFinder,CRT	1174266-1174295	30	MT074137	Bacteroides phage DAC16, complete genome	147918-147947	7	0.767
NC_012891_2	2.11\|1174266\|30\|NC_012891\|CRISPRCasFinder,CRT	1174266-1174295	30	MT074142	Bacteroides phage DAC23, complete genome	149949-149978	7	0.767
NC_012891_2	2.11\|1174266\|30\|NC_012891\|CRISPRCasFinder,CRT	1174266-1174295	30	MT074141	Bacteroides phage DAC22, complete genome	150393-150422	7	0.767
NC_012891_2	2.11\|1174266\|30\|NC_012891\|CRISPRCasFinder,CRT	1174266-1174295	30	MN692988	Marine virus AFVG_117M76, complete genome	31501-31530	7	0.767
NC_012891_2	2.11\|1174266\|30\|NC_012891\|CRISPRCasFinder,CRT	1174266-1174295	30	MT074146	Bacteroides phage SJC03, complete genome	137600-137629	7	0.767
NC_012891_2	2.11\|1174266\|30\|NC_012891\|CRISPRCasFinder,CRT	1174266-1174295	30	MT074139	Bacteroides phage DAC19, complete genome	150030-150059	7	0.767
NC_012891_2	2.11\|1174266\|30\|NC_012891\|CRISPRCasFinder,CRT	1174266-1174295	30	MT074140	Bacteroides phage DAC20, complete genome	150029-150058	7	0.767
NC_012891_2	2.11\|1174266\|30\|NC_012891\|CRISPRCasFinder,CRT	1174266-1174295	30	NZ_KY303941	Enterococcus faecalis strain 3 plasmid pGTC3, complete sequence	7136-7165	7	0.767
NC_012891_2	2.11\|1174266\|30\|NC_012891\|CRISPRCasFinder,CRT	1174266-1174295	30	NZ_KT897276	Clostridium botulinum strain INGR16-02E1 plasmid pINGR16-02E1, complete sequence	112814-112843	7	0.767
NC_012891_2	2.11\|1174266\|30\|NC_012891\|CRISPRCasFinder,CRT	1174266-1174295	30	NZ_KT897280	Clostridium botulinum strain FI1111E1 plasmid pFI1111E1, complete sequence	122540-122569	7	0.767
NC_012891_2	2.11\|1174266\|30\|NC_012891\|CRISPRCasFinder,CRT	1174266-1174295	30	NZ_KT897275	Clostridium botulinum strain IFR 12/29 plasmid p12/29, complete sequence	117744-117773	7	0.767
NC_012891_2	2.11\|1174266\|30\|NC_012891\|CRISPRCasFinder,CRT	1174266-1174295	30	NZ_KT897277	Clostridium botulinum strain ST0210E1 plasmid pST0210E1, complete sequence	112814-112843	7	0.767
NC_012891_2	2.11\|1174266\|30\|NC_012891\|CRISPRCasFinder,CRT	1174266-1174295	30	NZ_KT897278	Clostridium botulinum strain FWSKR40E1 plasmid pFWSKR40E1, complete sequence	119965-119994	7	0.767
NC_012891_2	2.11\|1174266\|30\|NC_012891\|CRISPRCasFinder,CRT	1174266-1174295	30	NZ_KT897279	Clostridium botulinum strain SWKR38E2 plasmid pSWKR38E2, complete sequence	121101-121130	7	0.767
NC_012891_2	2.11\|1174266\|30\|NC_012891\|CRISPRCasFinder,CRT	1174266-1174295	30	NC_011973	Bacillus cereus Q1 plasmid pBc239, complete sequence	129653-129682	7	0.767
NC_012891_2	2.11\|1174266\|30\|NC_012891\|CRISPRCasFinder,CRT	1174266-1174295	30	NC_011777	Bacillus cereus AH820 plasmid pAH820_272, complete sequence	10873-10902	7	0.767
NC_012891_2	2.11\|1174266\|30\|NC_012891\|CRISPRCasFinder,CRT	1174266-1174295	30	NZ_CP017256	Clostridium taeniosporum strain 1/k plasmid pCt3, complete sequence	79472-79501	7	0.767
NC_012891_2	2.11\|1174266\|30\|NC_012891\|CRISPRCasFinder,CRT	1174266-1174295	30	NZ_CP047086	Bacillus paranthracis strain BC307 plasmid pCE1, complete sequence	220458-220487	7	0.767
NC_012891_2	2.11\|1174266\|30\|NC_012891\|CRISPRCasFinder,CRT	1174266-1174295	30	NZ_CP022346	Bacillus thuringiensis strain c25 plasmid unnamed1, complete sequence	123281-123310	7	0.767
NC_012891_2	2.11\|1174266\|30\|NC_012891\|CRISPRCasFinder,CRT	1174266-1174295	30	MT774385	CrAssphage cr108_1, complete genome	27158-27187	7	0.767
NC_012891_2	2.14\|1174464\|30\|NC_012891\|CRISPRCasFinder,CRT,PILER-CR	1174464-1174493	30	FR682616	Roseovarius sp. 217 phage 1 partial genome sequence	73884-73913	7	0.767
NC_012891_2	2.14\|1174464\|30\|NC_012891\|CRISPRCasFinder,CRT,PILER-CR	1174464-1174493	30	FR719956	Roseovarius Plymouth Podovirus 1 partial sequence	74005-74034	7	0.767
NC_012891_2	2.16\|1174596\|30\|NC_012891\|CRISPRCasFinder,CRT,PILER-CR	1174596-1174625	30	NC_019763	Oscillatoria nigro-viridis PCC 7112 plasmid pOSC7112.01, complete sequence	103091-103120	7	0.767
NC_012891_3	3.1\|1601548\|33\|NC_012891\|PILER-CR	1601548-1601580	33	FR671407	Streptococcus phage 34117	34186-34218	7	0.788
NC_012891_3	3.1\|1601548\|33\|NC_012891\|PILER-CR	1601548-1601580	33	MK044828	Streptococcus phage 33888, complete genome	30752-30784	7	0.788
NC_012891_3	3.1\|1601548\|33\|NC_012891\|PILER-CR	1601548-1601580	33	KT337344	Streptococcus phage phiARI0274b, partial genome	31479-31511	7	0.788
NC_012891_3	3.1\|1601548\|33\|NC_012891\|PILER-CR	1601548-1601580	33	NC_031929	Streptococcus phage phiARI0468-1, complete genome	37495-37527	7	0.788
NC_012891_3	3.1\|1601548\|33\|NC_012891\|PILER-CR	1601548-1601580	33	FR671410	Streptococcus phage 8140	33103-33135	7	0.788
NC_012891_3	3.1\|1601548\|33\|NC_012891\|PILER-CR	1601548-1601580	33	KT337345	Streptococcus phage phiARI0285-1, partial genome	30688-30720	7	0.788
NC_012891_3	3.1\|1601548\|33\|NC_012891\|PILER-CR	1601548-1601580	33	NC_024370	Streptococcus phage IC1, complete sequence	37243-37275	7	0.788
NC_012891_3	3.1\|1601548\|33\|NC_012891\|PILER-CR	1601548-1601580	33	NC_024357	Streptococcus phage K13, complete sequence	35906-35938	7	0.788
NC_012891_3	3.1\|1601548\|33\|NC_012891\|PILER-CR	1601548-1601580	33	NC_031920	Streptococcus phage phiARI0004, complete genome	37601-37633	7	0.788
NC_012891_3	3.1\|1601548\|33\|NC_012891\|PILER-CR	1601548-1601580	33	FR671411	Streptococcus phage 2167	33473-33505	7	0.788
NC_012891_3	3.1\|1601548\|33\|NC_012891\|PILER-CR	1601548-1601580	33	KT337362	Streptococcus phage phiARI0598b, partial genome	33058-33090	7	0.788
NC_012891_3	3.1\|1601548\|33\|NC_012891\|PILER-CR	1601548-1601580	33	KT337340	Streptococcus phage phiARI0031, complete genome	39157-39189	7	0.788
NC_012891_3	3.1\|1601548\|33\|NC_012891\|PILER-CR	1601548-1601580	33	KT337342	Streptococcus phage phiARI0131-2, complete genome	31411-31443	7	0.788
NC_012891_3	3.1\|1601548\|33\|NC_012891\|PILER-CR	1601548-1601580	33	MK448917	Streptococcus phage Javan362, complete genome	2844-2876	7	0.788
NC_012891_3	3.1\|1601548\|33\|NC_012891\|PILER-CR	1601548-1601580	33	KY065457	Streptococcus phage IPP16, complete genome	3831-3863	7	0.788
NC_012891_3	3.1\|1601548\|33\|NC_012891\|PILER-CR	1601548-1601580	33	MK448891	Streptococcus phage Javan266, complete genome	2849-2881	7	0.788
NC_012891_3	3.1\|1601548\|33\|NC_012891\|PILER-CR	1601548-1601580	33	KY065486	Streptococcus phage IPP46, complete genome	2713-2745	7	0.788
NC_012891_3	3.1\|1601548\|33\|NC_012891\|PILER-CR	1601548-1601580	33	MK448740	Streptococcus phage Javan367, complete genome	2286-2318	7	0.788
NC_012891_3	3.1\|1601548\|33\|NC_012891\|PILER-CR	1601548-1601580	33	KY065500	Streptococcus phage IPP64, complete genome	2714-2746	7	0.788
NC_012891_3	3.1\|1601548\|33\|NC_012891\|PILER-CR	1601548-1601580	33	MK448910	Streptococcus phage Javan336, complete genome	3527-3559	7	0.788
NC_012891_3	3.1\|1601548\|33\|NC_012891\|PILER-CR	1601548-1601580	33	KY065449	Streptococcus phage IPP5, complete genome	4471-4503	7	0.788
NC_012891_3	3.1\|1601548\|33\|NC_012891\|PILER-CR	1601548-1601580	33	NC_010945	Streptococcus phage PH15, complete genome	2921-2953	7	0.788
NC_012891_2	2.3\|1173736\|30\|NC_012891\|CRISPRCasFinder,CRT,PILER-CR	1173736-1173765	30	NZ_CP053970	Bacillus thuringiensis strain FDAARGOS_796 plasmid unnamed2, complete sequence	303651-303680	8	0.733
NC_012891_2	2.3\|1173736\|30\|NC_012891\|CRISPRCasFinder,CRT,PILER-CR	1173736-1173765	30	NZ_CP053979	Bacillus thuringiensis strain FDAARGOS_795 plasmid unnamed3, complete sequence	211864-211893	8	0.733
NC_012891_2	2.3\|1173736\|30\|NC_012891\|CRISPRCasFinder,CRT,PILER-CR	1173736-1173765	30	NZ_CP013277	Bacillus thuringiensis serovar israelensis strain AM65-52 plasmid pAM65-52-2-350K, complete sequence	80585-80614	8	0.733
NC_012891_2	2.3\|1173736\|30\|NC_012891\|CRISPRCasFinder,CRT,PILER-CR	1173736-1173765	30	NZ_CP039723	Bacillus thuringiensis strain BT-59 plasmid p2, complete sequence	197586-197615	8	0.733
NC_012891_2	2.3\|1173736\|30\|NC_012891\|CRISPRCasFinder,CRT,PILER-CR	1173736-1173765	30	NZ_CP009348	Bacillus thuringiensis HD1002 plasmid 2, complete sequence	80585-80614	8	0.733
NC_012891_2	2.3\|1173736\|30\|NC_012891\|CRISPRCasFinder,CRT,PILER-CR	1173736-1173765	30	NZ_CP045024	Bacillus thuringiensis strain JW-1 plasmid p2, complete sequence	80585-80614	8	0.733
NC_012891_2	2.3\|1173736\|30\|NC_012891\|CRISPRCasFinder,CRT,PILER-CR	1173736-1173765	30	NC_018516	Bacillus thuringiensis HD-789 plasmid pBTHD789-1, complete sequence	126797-126826	8	0.733
NC_012891_2	2.3\|1173736\|30\|NC_012891\|CRISPRCasFinder,CRT,PILER-CR	1173736-1173765	30	NZ_CP009334	Bacillus thuringiensis strain HD1011 plasmid 2, complete sequence	60993-61022	8	0.733
NC_012891_2	2.4\|1173802\|30\|NC_012891\|CRISPRCasFinder,CRT,PILER-CR	1173802-1173831	30	NZ_CP014308	Burkholderia sp. PAMC 26561 plasmid unnamed1, complete sequence	339808-339837	8	0.733
NC_012891_2	2.4\|1173802\|30\|NC_012891\|CRISPRCasFinder,CRT,PILER-CR	1173802-1173831	30	NZ_CP014309	Burkholderia sp. PAMC 26561 plasmid unnamed2, complete sequence	495298-495327	8	0.733
NC_012891_2	2.9\|1174134\|30\|NC_012891\|CRISPRCasFinder,CRT	1174134-1174163	30	NZ_CP015006	Aminobacter aminovorans strain KCTC 2477 plasmid pAA01, complete sequence	414805-414834	8	0.733
NC_012891_2	2.11\|1174266\|30\|NC_012891\|CRISPRCasFinder,CRT	1174266-1174295	30	NZ_LR214986	Mycoplasma cynos strain NCTC10142 plasmid 13	358024-358053	8	0.733
NC_012891_2	2.11\|1174266\|30\|NC_012891\|CRISPRCasFinder,CRT	1174266-1174295	30	MH319743	Marine virus AG-345-E15 Ga0172270_13 genomic sequence	11504-11533	8	0.733
NC_012891_2	2.15\|1174530\|30\|NC_012891\|CRISPRCasFinder,CRT,PILER-CR	1174530-1174559	30	NZ_CP030933	Enterococcus gilvus strain CR1 plasmid pCR1A, complete sequence	29277-29306	8	0.733
NC_012891_2	2.15\|1174530\|30\|NC_012891\|CRISPRCasFinder,CRT,PILER-CR	1174530-1174559	30	NC_028969	Brevibacillus phage Osiris, complete genome	25705-25734	8	0.733
NC_012891_2	2.15\|1174530\|30\|NC_012891\|CRISPRCasFinder,CRT,PILER-CR	1174530-1174559	30	NC_041976	Brevibacillus phage Jimmer2, complete genome	25737-25766	8	0.733
NC_012891_2	2.15\|1174530\|30\|NC_012891\|CRISPRCasFinder,CRT,PILER-CR	1174530-1174559	30	KT151958	Brevibacillus phage Powder, complete genome	25742-25771	8	0.733
NC_012891_2	2.15\|1174530\|30\|NC_012891\|CRISPRCasFinder,CRT,PILER-CR	1174530-1174559	30	KC595515	Brevibacillus phage Jimmer1, complete genome	25737-25766	8	0.733
NC_012891_2	2.16\|1174596\|30\|NC_012891\|CRISPRCasFinder,CRT,PILER-CR	1174596-1174625	30	NC_019679	Rivularia sp. PCC 7116 plasmid pRIV7116.01, complete sequence	22892-22921	8	0.733
NC_012891_3	3.1\|1601548\|33\|NC_012891\|PILER-CR	1601548-1601580	33	KT337341	Streptococcus phage phiARI0131-1, complete genome	1917-1949	8	0.758
NC_012891_3	3.1\|1601548\|33\|NC_012891\|PILER-CR	1601548-1601580	33	KT337352	Streptococcus phage phiARI0460-1, complete genome	37998-38030	8	0.758
NC_012891_3	3.1\|1601548\|33\|NC_012891\|PILER-CR	1601548-1601580	33	FR671406	Streptococcus phage 040922	36985-37017	8	0.758
NC_012891_3	3.1\|1601548\|33\|NC_012891\|PILER-CR	1601548-1601580	33	MK044829	Streptococcus phage 109751, complete genome	3241-3273	8	0.758
NC_012891_3	3.1\|1601548\|33\|NC_012891\|PILER-CR	1601548-1601580	33	KY065480	Streptococcus phage IPP40, complete genome	3421-3453	8	0.758
NC_012891_3	3.1\|1601548\|33\|NC_012891\|PILER-CR	1601548-1601580	33	KY065478	Streptococcus phage IPP38, complete genome	3420-3452	8	0.758
NC_012891_3	3.1\|1601548\|33\|NC_012891\|PILER-CR	1601548-1601580	33	KY065497	Streptococcus phage IPP61, complete genome	3421-3453	8	0.758
NC_012891_3	3.1\|1601548\|33\|NC_012891\|PILER-CR	1601548-1601580	33	KY065451	Streptococcus phage IPP9, complete genome	3088-3120	8	0.758
NC_012891_3	3.1\|1601548\|33\|NC_012891\|PILER-CR	1601548-1601580	33	KY065488	Streptococcus phage IPP50, complete genome	3226-3258	8	0.758
NC_012891_3	3.1\|1601548\|33\|NC_012891\|PILER-CR	1601548-1601580	33	KJ417497	Streptococcus phage Spn1, complete genome	3523-3555	8	0.758
NC_012891_3	3.1\|1601548\|33\|NC_012891\|PILER-CR	1601548-1601580	33	KY065467	Streptococcus phage IPP26, complete genome	3226-3258	8	0.758
NC_012891_2	2.14\|1174464\|30\|NC_012891\|CRISPRCasFinder,CRT,PILER-CR	1174464-1174493	30	NZ_CP009975	Pseudomonas putida S12 plasmid pTTS12, complete sequence	123965-123994	9	0.7
NC_012891_2	2.14\|1174464\|30\|NC_012891\|CRISPRCasFinder,CRT,PILER-CR	1174464-1174493	30	NZ_CP040126	Pseudomonas aeruginosa strain PA298 plasmid pBM908, complete sequence	120972-121001	9	0.7
NC_012891_2	2.14\|1174464\|30\|NC_012891\|CRISPRCasFinder,CRT,PILER-CR	1174464-1174493	30	NZ_CP016215	Pseudomonas aeruginosa strain PA121617 plasmid pBM413, complete sequence	193395-193424	9	0.7
NC_012891_2	2.14\|1174464\|30\|NC_012891\|CRISPRCasFinder,CRT,PILER-CR	1174464-1174493	30	NZ_CP029096	Pseudomonas aeruginosa strain AR439 plasmid unnamed2, complete sequence	146188-146217	9	0.7
NC_012891_2	2.14\|1174464\|30\|NC_012891\|CRISPRCasFinder,CRT,PILER-CR	1174464-1174493	30	NZ_CP045917	Pseudomonas aeruginosa strain CF39S plasmid pCF39S, complete sequence	111911-111940	9	0.7
NC_012891_2	2.14\|1174464\|30\|NC_012891\|CRISPRCasFinder,CRT,PILER-CR	1174464-1174493	30	CP003983	Candidatus Tremblaya phenacola PAVE plasmid, complete sequence	553-582	9	0.7
NC_012891_2	2.14\|1174464\|30\|NC_012891\|CRISPRCasFinder,CRT,PILER-CR	1174464-1174493	30	MF344571	Pseudomonas aeruginosa plasmid pR31014-IMP, complete sequence	111693-111722	9	0.7
NC_012891_2	2.14\|1174464\|30\|NC_012891\|CRISPRCasFinder,CRT,PILER-CR	1174464-1174493	30	MF344568	Pseudomonas aeruginosa plasmid p727-IMP, complete sequence	112945-112974	9	0.7
NC_012891_2	2.14\|1174464\|30\|NC_012891\|CRISPRCasFinder,CRT,PILER-CR	1174464-1174493	30	MF344570	Pseudomonas aeruginosa plasmid pA681-IMP, complete sequence	112691-112720	9	0.7
NC_012891_2	2.14\|1174464\|30\|NC_012891\|CRISPRCasFinder,CRT,PILER-CR	1174464-1174493	30	CP027478	Pseudomonas koreensis strain P19E3 plasmid p1, complete sequence	186403-186432	9	0.7
NC_012891_2	2.14\|1174464\|30\|NC_012891\|CRISPRCasFinder,CRT,PILER-CR	1174464-1174493	30	NZ_CP015879	Pseudomonas citronellolis strain SJTE-3 plasmid pRBL16, complete sequence	41581-41610	9	0.7
NC_012891_2	2.14\|1174464\|30\|NC_012891\|CRISPRCasFinder,CRT,PILER-CR	1174464-1174493	30	NZ_KY883660	Pseudomonas putida strain SY153 plasmid pSY153-MDR, complete sequence	115341-115370	9	0.7
NC_012891_3	3.2\|1601618\|37\|NC_012891\|PILER-CR	1601618-1601654	37	MN694381	Marine virus AFVG_250M1042, complete genome	28904-28940	10	0.73
NC_012891_3	3.2\|1601618\|37\|NC_012891\|PILER-CR	1601618-1601654	37	MK496795	Capybara microvirus Cap3_SP_446, complete genome	3464-3500	10	0.73
NC_012891_3	3.2\|1601618\|37\|NC_012891\|PILER-CR	1601618-1601654	37	NZ_CP034130	Klebsiella quasipneumoniae strain G4584 plasmid pG4584_218.9Kb, complete sequence	32075-32111	11	0.703
NC_012891_3	3.2\|1601618\|37\|NC_012891\|PILER-CR	1601618-1601654	37	NZ_CP034138	Klebsiella quasipneumoniae subsp. similipneumoniae strain G747 plasmid pG747_218.9Kb, complete sequence	32074-32110	11	0.703
NC_012891_3	3.2\|1601618\|37\|NC_012891\|PILER-CR	1601618-1601654	37	NZ_CP017473	Enterobacter cloacae strain M12X01451 plasmid pM12X01451, complete sequence	46942-46978	11	0.703
NC_012891_3	3.2\|1601618\|37\|NC_012891\|PILER-CR	1601618-1601654	37	NZ_CP010123	Escherichia coli strain C5 plasmid A, complete genome	146872-146908	11	0.703

1. spacer 2.1|1173604|30|NC_012891|CRISPRCasFinder,CRT matches to MK448681 (Streptococcus phage Javan141, complete genome) position: , mismatch: 0, identity: 1.0

acagttaaatagctttggtatcttgtcgat	CRISPR spacer
acagttaaatagctttggtatcttgtcgat	Protospacer
******************************

2. spacer 2.1|1173604|30|NC_012891|CRISPRCasFinder,CRT matches to MK448690 (Streptococcus phage Javan169, complete genome) position: , mismatch: 0, identity: 1.0

acagttaaatagctttggtatcttgtcgat	CRISPR spacer
acagttaaatagctttggtatcttgtcgat	Protospacer
******************************

3. spacer 2.1|1173604|30|NC_012891|CRISPRCasFinder,CRT matches to MK448856 (Streptococcus phage Javan158, complete genome) position: , mismatch: 0, identity: 1.0

acagttaaatagctttggtatcttgtcgat	CRISPR spacer
acagttaaatagctttggtatcttgtcgat	Protospacer
******************************

4. spacer 2.4|1173802|30|NC_012891|CRISPRCasFinder,CRT,PILER-CR matches to MK448769 (Streptococcus phage Javan471, complete genome) position: , mismatch: 0, identity: 1.0

aaaagtggctatcacgctgacacagactaa	CRISPR spacer
aaaagtggctatcacgctgacacagactaa	Protospacer
******************************

5. spacer 2.4|1173802|30|NC_012891|CRISPRCasFinder,CRT,PILER-CR matches to MK448684 (Streptococcus phage Javan151, complete genome) position: , mismatch: 0, identity: 1.0

aaaagtggctatcacgctgacacagactaa	CRISPR spacer
aaaagtggctatcacgctgacacagactaa	Protospacer
******************************

6. spacer 2.4|1173802|30|NC_012891|CRISPRCasFinder,CRT,PILER-CR matches to MK448679 (Streptococcus phage Javan137, complete genome) position: , mismatch: 0, identity: 1.0

aaaagtggctatcacgctgacacagactaa	CRISPR spacer
aaaagtggctatcacgctgacacagactaa	Protospacer
******************************

7. spacer 2.5|1173868|30|NC_012891|CRISPRCasFinder,CRT,PILER-CR matches to MK448834 (Streptococcus phage Javan91, complete genome) position: , mismatch: 0, identity: 1.0

aacactgattgttccaattgtatttgtaaa	CRISPR spacer
aacactgattgttccaattgtatttgtaaa	Protospacer
******************************

8. spacer 2.5|1173868|30|NC_012891|CRISPRCasFinder,CRT,PILER-CR matches to KT388093 (Streptococcus phage A25, complete genome) position: , mismatch: 0, identity: 1.0

aacactgattgttccaattgtatttgtaaa	CRISPR spacer
aacactgattgttccaattgtatttgtaaa	Protospacer
******************************

9. spacer 2.5|1173868|30|NC_012891|CRISPRCasFinder,CRT,PILER-CR matches to MK449009 (Streptococcus phage Javan88, complete genome) position: , mismatch: 0, identity: 1.0

aacactgattgttccaattgtatttgtaaa	CRISPR spacer
aacactgattgttccaattgtatttgtaaa	Protospacer
******************************

10. spacer 2.5|1173868|30|NC_012891|CRISPRCasFinder,CRT,PILER-CR matches to KY349816 (Streptococcus phage Str01, complete genome) position: , mismatch: 0, identity: 1.0

aacactgattgttccaattgtatttgtaaa	CRISPR spacer
aacactgattgttccaattgtatttgtaaa	Protospacer
******************************

11. spacer 2.6|1173934|30|NC_012891|CRISPRCasFinder,CRT,PILER-CR matches to MK448848 (Streptococcus phage Javan126, complete genome) position: , mismatch: 0, identity: 1.0

gtcacgctgatatatgtcacccaaatatag	CRISPR spacer
gtcacgctgatatatgtcacccaaatatag	Protospacer
******************************

12. spacer 2.6|1173934|30|NC_012891|CRISPRCasFinder,CRT,PILER-CR matches to MK448857 (Streptococcus phage Javan164, complete genome) position: , mismatch: 0, identity: 1.0

gtcacgctgatatatgtcacccaaatatag	CRISPR spacer
gtcacgctgatatatgtcacccaaatatag	Protospacer
******************************

13. spacer 2.6|1173934|30|NC_012891|CRISPRCasFinder,CRT,PILER-CR matches to MK448677 (Streptococcus phage Javan133, complete genome) position: , mismatch: 0, identity: 1.0

gtcacgctgatatatgtcacccaaatatag	CRISPR spacer
gtcacgctgatatatgtcacccaaatatag	Protospacer
******************************

14. spacer 2.6|1173934|30|NC_012891|CRISPRCasFinder,CRT,PILER-CR matches to NC_009018 (Streptococcus phage phi3396, complete genome) position: , mismatch: 0, identity: 1.0

gtcacgctgatatatgtcacccaaatatag	CRISPR spacer
gtcacgctgatatatgtcacccaaatatag	Protospacer
******************************

15. spacer 2.6|1173934|30|NC_012891|CRISPRCasFinder,CRT,PILER-CR matches to MK448682 (Streptococcus phage Javan143, complete genome) position: , mismatch: 0, identity: 1.0

gtcacgctgatatatgtcacccaaatatag	CRISPR spacer
gtcacgctgatatatgtcacccaaatatag	Protospacer
******************************

16. spacer 2.6|1173934|30|NC_012891|CRISPRCasFinder,CRT,PILER-CR matches to MK448854 (Streptococcus phage Javan146, complete genome) position: , mismatch: 0, identity: 1.0

gtcacgctgatatatgtcacccaaatatag	CRISPR spacer
gtcacgctgatatatgtcacccaaatatag	Protospacer
******************************

17. spacer 2.6|1173934|30|NC_012891|CRISPRCasFinder,CRT,PILER-CR matches to MK448680 (Streptococcus phage Javan139, complete genome) position: , mismatch: 0, identity: 1.0

gtcacgctgatatatgtcacccaaatatag	CRISPR spacer
gtcacgctgatatatgtcacccaaatatag	Protospacer
******************************

18. spacer 2.8|1174068|30|NC_012891|CRISPRCasFinder,CRT matches to MK448690 (Streptococcus phage Javan169, complete genome) position: , mismatch: 0, identity: 1.0

gcaaaagctttctcatattttactcgattc	CRISPR spacer
gcaaaagctttctcatattttactcgattc	Protospacer
******************************

19. spacer 2.10|1174200|30|NC_012891|CRISPRCasFinder,CRT matches to MK448769 (Streptococcus phage Javan471, complete genome) position: , mismatch: 0, identity: 1.0

aatacaatctcatgattcgcaaacatcatg	CRISPR spacer
aatacaatctcatgattcgcaaacatcatg	Protospacer
******************************

20. spacer 2.10|1174200|30|NC_012891|CRISPRCasFinder,CRT matches to MK448684 (Streptococcus phage Javan151, complete genome) position: , mismatch: 0, identity: 1.0

aatacaatctcatgattcgcaaacatcatg	CRISPR spacer
aatacaatctcatgattcgcaaacatcatg	Protospacer
******************************

21. spacer 2.10|1174200|30|NC_012891|CRISPRCasFinder,CRT matches to MK448680 (Streptococcus phage Javan139, complete genome) position: , mismatch: 0, identity: 1.0

aatacaatctcatgattcgcaaacatcatg	CRISPR spacer
aatacaatctcatgattcgcaaacatcatg	Protospacer
******************************

22. spacer 2.11|1174266|30|NC_012891|CRISPRCasFinder,CRT matches to MK448848 (Streptococcus phage Javan126, complete genome) position: , mismatch: 0, identity: 1.0

catattctattaatcctttatttaaaaaat	CRISPR spacer
catattctattaatcctttatttaaaaaat	Protospacer
******************************

23. spacer 2.11|1174266|30|NC_012891|CRISPRCasFinder,CRT matches to MK448857 (Streptococcus phage Javan164, complete genome) position: , mismatch: 0, identity: 1.0

catattctattaatcctttatttaaaaaat	CRISPR spacer
catattctattaatcctttatttaaaaaat	Protospacer
******************************

24. spacer 2.11|1174266|30|NC_012891|CRISPRCasFinder,CRT matches to MK448677 (Streptococcus phage Javan133, complete genome) position: , mismatch: 0, identity: 1.0

catattctattaatcctttatttaaaaaat	CRISPR spacer
catattctattaatcctttatttaaaaaat	Protospacer
******************************

25. spacer 2.13|1174398|30|NC_012891|CRISPRCasFinder,CRT matches to MK448792 (Streptococcus phage Javan521, complete genome) position: , mismatch: 0, identity: 1.0

aagcatcatagtaaacatatctagcacgct	CRISPR spacer
aagcatcatagtaaacatatctagcacgct	Protospacer
******************************

26. spacer 2.13|1174398|30|NC_012891|CRISPRCasFinder,CRT matches to NC_009018 (Streptococcus phage phi3396, complete genome) position: , mismatch: 0, identity: 1.0

aagcatcatagtaaacatatctagcacgct	CRISPR spacer
aagcatcatagtaaacatatctagcacgct	Protospacer
******************************

27. spacer 2.13|1174398|30|NC_012891|CRISPRCasFinder,CRT matches to MK448679 (Streptococcus phage Javan137, complete genome) position: , mismatch: 0, identity: 1.0

aagcatcatagtaaacatatctagcacgct	CRISPR spacer
aagcatcatagtaaacatatctagcacgct	Protospacer
******************************

28. spacer 2.13|1174398|30|NC_012891|CRISPRCasFinder,CRT matches to MK448682 (Streptococcus phage Javan143, complete genome) position: , mismatch: 0, identity: 1.0

aagcatcatagtaaacatatctagcacgct	CRISPR spacer
aagcatcatagtaaacatatctagcacgct	Protospacer
******************************

29. spacer 2.13|1174398|30|NC_012891|CRISPRCasFinder,CRT matches to MK448770 (Streptococcus phage Javan477, complete genome) position: , mismatch: 0, identity: 1.0

aagcatcatagtaaacatatctagcacgct	CRISPR spacer
aagcatcatagtaaacatatctagcacgct	Protospacer
******************************

30. spacer 2.16|1174596|30|NC_012891|CRISPRCasFinder,CRT,PILER-CR matches to KT388093 (Streptococcus phage A25, complete genome) position: , mismatch: 0, identity: 1.0

atggtacaagtaaaactaccgccccagtta	CRISPR spacer
atggtacaagtaaaactaccgccccagtta	Protospacer
******************************

31. spacer 2.16|1174596|30|NC_012891|CRISPRCasFinder,CRT,PILER-CR matches to KY349816 (Streptococcus phage Str01, complete genome) position: , mismatch: 0, identity: 1.0

atggtacaagtaaaactaccgccccagtta	CRISPR spacer
atggtacaagtaaaactaccgccccagtta	Protospacer
******************************

32. spacer 2.18|1174728|30|NC_012891|CRISPRCasFinder,CRT,PILER-CR matches to MK449010 (Streptococcus phage Javan90, complete genome) position: , mismatch: 0, identity: 1.0

ttctgtctagcccttgttcttgactcgtct	CRISPR spacer
ttctgtctagcccttgttcttgactcgtct	Protospacer
******************************

33. spacer 2.18|1174728|30|NC_012891|CRISPRCasFinder,CRT,PILER-CR matches to MK448681 (Streptococcus phage Javan141, complete genome) position: , mismatch: 0, identity: 1.0

ttctgtctagcccttgttcttgactcgtct	CRISPR spacer
ttctgtctagcccttgttcttgactcgtct	Protospacer
******************************

34. spacer 2.18|1174728|30|NC_012891|CRISPRCasFinder,CRT,PILER-CR matches to MK448833 (Streptococcus phage Javan87, complete genome) position: , mismatch: 0, identity: 1.0

ttctgtctagcccttgttcttgactcgtct	CRISPR spacer
ttctgtctagcccttgttcttgactcgtct	Protospacer
******************************

35. spacer 2.18|1174728|30|NC_012891|CRISPRCasFinder,CRT,PILER-CR matches to MK448856 (Streptococcus phage Javan158, complete genome) position: , mismatch: 0, identity: 1.0

ttctgtctagcccttgttcttgactcgtct	CRISPR spacer
ttctgtctagcccttgttcttgactcgtct	Protospacer
******************************

36. spacer 3.1|1601548|33|NC_012891|PILER-CR matches to MK448681 (Streptococcus phage Javan141, complete genome) position: , mismatch: 0, identity: 1.0

aagcttttgtttccttaagcttgattttattat	CRISPR spacer
aagcttttgtttccttaagcttgattttattat	Protospacer
*********************************

37. spacer 4.1|2067357|45|NC_012891|CRISPRCasFinder matches to MK448333 (Streptococcus satellite phage Javan145, complete genome) position: , mismatch: 0, identity: 1.0

ttttgcaaaatctatattaacgcaaataaatttggttgccaagat	CRISPR spacer
ttttgcaaaatctatattaacgcaaataaatttggttgccaagat	Protospacer
*********************************************

38. spacer 4.1|2067357|45|NC_012891|CRISPRCasFinder matches to MK448340 (Streptococcus satellite phage Javan156, complete genome) position: , mismatch: 0, identity: 1.0

ttttgcaaaatctatattaacgcaaataaatttggttgccaagat	CRISPR spacer
ttttgcaaaatctatattaacgcaaataaatttggttgccaagat	Protospacer
*********************************************

39. spacer 2.4|1173802|30|NC_012891|CRISPRCasFinder,CRT,PILER-CR matches to MK448960 (Streptococcus phage Javan492, complete genome) position: , mismatch: 1, identity: 0.967

aaaagtggctatcacgctgacacagactaa	CRISPR spacer
aaaagtggctatcacgctgacacaggctaa	Protospacer
*************************.****

40. spacer 2.4|1173802|30|NC_012891|CRISPRCasFinder,CRT,PILER-CR matches to MK448973 (Streptococcus phage Javan522, complete genome) position: , mismatch: 1, identity: 0.967

aaaagtggctatcacgctgacacagactaa	CRISPR spacer
aaaagtggctatcacgctgacacaggctaa	Protospacer
*************************.****

41. spacer 2.4|1173802|30|NC_012891|CRISPRCasFinder,CRT,PILER-CR matches to MK448762 (Streptococcus phage Javan447, complete genome) position: , mismatch: 1, identity: 0.967

aaaagtggctatcacgctgacacagactaa	CRISPR spacer
aaaagtggctatcacgctgacacaggctaa	Protospacer
*************************.****

42. spacer 2.4|1173802|30|NC_012891|CRISPRCasFinder,CRT,PILER-CR matches to MK448952 (Streptococcus phage Javan472, complete genome) position: , mismatch: 1, identity: 0.967

aaaagtggctatcacgctgacacagactaa	CRISPR spacer
aaaagtggctatcacgctgacacaggctaa	Protospacer
*************************.****

43. spacer 2.4|1173802|30|NC_012891|CRISPRCasFinder,CRT,PILER-CR matches to NC_004585 (Streptococcus prophage 315.2, complete genome) position: , mismatch: 1, identity: 0.967

aaaagtggctatcacgctgacacagactaa	CRISPR spacer
aaaagtggctatcacgctgacacaggctaa	Protospacer
*************************.****

44. spacer 2.4|1173802|30|NC_012891|CRISPRCasFinder,CRT,PILER-CR matches to MK448966 (Streptococcus phage Javan508, complete genome) position: , mismatch: 1, identity: 0.967

aaaagtggctatcacgctgacacagactaa	CRISPR spacer
aaaagtggctatcacgctgacacaggctaa	Protospacer
*************************.****

45. spacer 2.4|1173802|30|NC_012891|CRISPRCasFinder,CRT,PILER-CR matches to NC_009018 (Streptococcus phage phi3396, complete genome) position: , mismatch: 1, identity: 0.967

aaaagtggctatcacgctgacacagactaa	CRISPR spacer
aaaagtggctatcacgctgacacaggctaa	Protospacer
*************************.****

46. spacer 2.4|1173802|30|NC_012891|CRISPRCasFinder,CRT,PILER-CR matches to MK448959 (Streptococcus phage Javan488, complete genome) position: , mismatch: 1, identity: 0.967

aaaagtggctatcacgctgacacagactaa	CRISPR spacer
aaaagtggctatcacgctgacacaggctaa	Protospacer
*************************.****

47. spacer 2.4|1173802|30|NC_012891|CRISPRCasFinder,CRT,PILER-CR matches to NC_004587 (Streptococcus prophage 315.4, complete genome) position: , mismatch: 1, identity: 0.967

aaaagtggctatcacgctgacacagactaa	CRISPR spacer
aaaagtggctatcacgctgacacaggctaa	Protospacer
*************************.****

48. spacer 2.4|1173802|30|NC_012891|CRISPRCasFinder,CRT,PILER-CR matches to NC_003157 (Streptococcus pyogenes strain NIH1 putative methionine sulfoxide reductase gene, complete cds; and integrated temperate phage PhiNIH1.1, complete genome) position: , mismatch: 1, identity: 0.967

aaaagtggctatcacgctgacacagactaa	CRISPR spacer
aaaagtggctatcacgctgacacaggctaa	Protospacer
*************************.****

49. spacer 2.4|1173802|30|NC_012891|CRISPRCasFinder,CRT,PILER-CR matches to MK448682 (Streptococcus phage Javan143, complete genome) position: , mismatch: 1, identity: 0.967

aaaagtggctatcacgctgacacagactaa	CRISPR spacer
aaaagtggctatcacgctgacacaggctaa	Protospacer
*************************.****

50. spacer 2.4|1173802|30|NC_012891|CRISPRCasFinder,CRT,PILER-CR matches to MK448766 (Streptococcus phage Javan465, complete genome) position: , mismatch: 1, identity: 0.967

aaaagtggctatcacgctgacacagactaa	CRISPR spacer
aaaagtggctatcacgctgacacaggctaa	Protospacer
*************************.****

51. spacer 2.4|1173802|30|NC_012891|CRISPRCasFinder,CRT,PILER-CR matches to MK448778 (Streptococcus phage Javan493, complete genome) position: , mismatch: 1, identity: 0.967

aaaagtggctatcacgctgacacagactaa	CRISPR spacer
aaaagtggctatcacgctgacacaggctaa	Protospacer
*************************.****

52. spacer 2.4|1173802|30|NC_012891|CRISPRCasFinder,CRT,PILER-CR matches to MK448977 (Streptococcus phage Javan530, complete genome) position: , mismatch: 1, identity: 0.967

aaaagtggctatcacgctgacacagactaa	CRISPR spacer
aaaagtggctatcacgctgacacaggctaa	Protospacer
*************************.****

53. spacer 2.4|1173802|30|NC_012891|CRISPRCasFinder,CRT,PILER-CR matches to MK448680 (Streptococcus phage Javan139, complete genome) position: , mismatch: 1, identity: 0.967

aaaagtggctatcacgctgacacagactaa	CRISPR spacer
aaaagtgactatcacgctgacacagactaa	Protospacer
*******.**********************

54. spacer 2.4|1173802|30|NC_012891|CRISPRCasFinder,CRT,PILER-CR matches to MK448845 (Streptococcus phage Javan118, complete genome) position: , mismatch: 1, identity: 0.967

aaaagtggctatcacgctgacacagactaa	CRISPR spacer
aaaagtggctatcacgctgacacaggctaa	Protospacer
*************************.****

55. spacer 2.4|1173802|30|NC_012891|CRISPRCasFinder,CRT,PILER-CR matches to MK448788 (Streptococcus phage Javan511, complete genome) position: , mismatch: 1, identity: 0.967

aaaagtggctatcacgctgacacagactaa	CRISPR spacer
aaaagtggctatcacgctgacacaggctaa	Protospacer
*************************.****

56. spacer 2.4|1173802|30|NC_012891|CRISPRCasFinder,CRT,PILER-CR matches to MK448950 (Streptococcus phage Javan464, complete genome) position: , mismatch: 1, identity: 0.967

aaaagtggctatcacgctgacacagactaa	CRISPR spacer
aaaagtagctatcacgctgacacagactaa	Protospacer
******.***********************

57. spacer 2.4|1173802|30|NC_012891|CRISPRCasFinder,CRT,PILER-CR matches to MK448957 (Streptococcus phage Javan484, complete genome) position: , mismatch: 1, identity: 0.967

aaaagtggctatcacgctgacacagactaa	CRISPR spacer
aaaagtggctatcacgctgacacaggctaa	Protospacer
*************************.****

58. spacer 2.4|1173802|30|NC_012891|CRISPRCasFinder,CRT,PILER-CR matches to MK448975 (Streptococcus phage Javan526, complete genome) position: , mismatch: 1, identity: 0.967

aaaagtggctatcacgctgacacagactaa	CRISPR spacer
aaaagtggctatcacgctgacacaggctaa	Protospacer
*************************.****

59. spacer 2.4|1173802|30|NC_012891|CRISPRCasFinder,CRT,PILER-CR matches to MK448678 (Streptococcus phage Javan135, complete genome) position: , mismatch: 1, identity: 0.967

aaaagtggctatcacgctgacacagactaa	CRISPR spacer
aaaagtgactatcacgctgacacagactaa	Protospacer
*******.**********************

60. spacer 2.4|1173802|30|NC_012891|CRISPRCasFinder,CRT,PILER-CR matches to MK448782 (Streptococcus phage Javan501, complete genome) position: , mismatch: 1, identity: 0.967

aaaagtggctatcacgctgacacagactaa	CRISPR spacer
aaaagtggctatcacgctgacacaggctaa	Protospacer
*************************.****

61. spacer 2.4|1173802|30|NC_012891|CRISPRCasFinder,CRT,PILER-CR matches to MK448673 (Streptococcus phage Javan119, complete genome) position: , mismatch: 1, identity: 0.967

aaaagtggctatcacgctgacacagactaa	CRISPR spacer
aaaagtggctatcacgctgacacaggctaa	Protospacer
*************************.****

62. spacer 2.6|1173934|30|NC_012891|CRISPRCasFinder,CRT,PILER-CR matches to MK448769 (Streptococcus phage Javan471, complete genome) position: , mismatch: 1, identity: 0.967

gtcacgctgatatatgtcacccaaatatag	CRISPR spacer
gtcacgctgatatatgttacccaaatatag	Protospacer
*****************.************

63. spacer 2.6|1173934|30|NC_012891|CRISPRCasFinder,CRT,PILER-CR matches to MK448684 (Streptococcus phage Javan151, complete genome) position: , mismatch: 1, identity: 0.967

gtcacgctgatatatgtcacccaaatatag	CRISPR spacer
gtcacgctgatatatgttacccaaatatag	Protospacer
*****************.************

64. spacer 2.7|1174000|32|NC_012891|CRISPRCasFinder,CRT,PILER-CR matches to MK448685 (Streptococcus phage Javan155, complete genome) position: , mismatch: 1, identity: 0.969

acgctttagcagatggagcggggcttacgagg	CRISPR spacer
acgctttagcagatggagcggggcttacgaag	Protospacer
******************************.*

65. spacer 2.7|1174000|32|NC_012891|CRISPRCasFinder,CRT,PILER-CR matches to MK448791 (Streptococcus phage Javan517, complete genome) position: , mismatch: 1, identity: 0.969

acgctttagcagatggagcggggcttacgagg	CRISPR spacer
acgctttagcagatggagcggggcttacgaag	Protospacer
******************************.*

66. spacer 2.7|1174000|32|NC_012891|CRISPRCasFinder,CRT,PILER-CR matches to NC_004587 (Streptococcus prophage 315.4, complete genome) position: , mismatch: 1, identity: 0.969

acgctttagcagatggagcggggcttacgagg	CRISPR spacer
acgctttagcagatggagcggggcttacgaag	Protospacer
******************************.*

67. spacer 2.7|1174000|32|NC_012891|CRISPRCasFinder,CRT,PILER-CR matches to MK448690 (Streptococcus phage Javan169, complete genome) position: , mismatch: 1, identity: 0.969

acgctttagcagatggagcggggcttacgagg	CRISPR spacer
acgctttagcagatggagcggggcttacgaag	Protospacer
******************************.*

68. spacer 2.7|1174000|32|NC_012891|CRISPRCasFinder,CRT,PILER-CR matches to NC_003157 (Streptococcus pyogenes strain NIH1 putative methionine sulfoxide reductase gene, complete cds; and integrated temperate phage PhiNIH1.1, complete genome) position: , mismatch: 1, identity: 0.969

acgctttagcagatggagcggggcttacgagg	CRISPR spacer
acgctttagcagatggagcggggcttacgaag	Protospacer
******************************.*

69. spacer 2.7|1174000|32|NC_012891|CRISPRCasFinder,CRT,PILER-CR matches to MK448977 (Streptococcus phage Javan530, complete genome) position: , mismatch: 1, identity: 0.969

acgctttagcagatggagcggggcttacgagg	CRISPR spacer
acgctttagcagatggagcggggcttacgaag	Protospacer
******************************.*

70. spacer 2.7|1174000|32|NC_012891|CRISPRCasFinder,CRT,PILER-CR matches to MK448854 (Streptococcus phage Javan146, complete genome) position: , mismatch: 1, identity: 0.969

acgctttagcagatggagcggggcttacgagg	CRISPR spacer
acgctttagcagatggagcggggcttacgaag	Protospacer
******************************.*

71. spacer 2.7|1174000|32|NC_012891|CRISPRCasFinder,CRT,PILER-CR matches to MK448788 (Streptococcus phage Javan511, complete genome) position: , mismatch: 1, identity: 0.969

acgctttagcagatggagcggggcttacgagg	CRISPR spacer
acgctttagcagatggagcggggcttacgaag	Protospacer
******************************.*

72. spacer 2.7|1174000|32|NC_012891|CRISPRCasFinder,CRT,PILER-CR matches to MK448853 (Streptococcus phage Javan144, complete genome) position: , mismatch: 1, identity: 0.969

acgctttagcagatggagcggggcttacgagg	CRISPR spacer
acgctttagcagatggagcggggcttacgaag	Protospacer
******************************.*

73. spacer 2.7|1174000|32|NC_012891|CRISPRCasFinder,CRT,PILER-CR matches to MK448683 (Streptococcus phage Javan149, complete genome) position: , mismatch: 1, identity: 0.969

acgctttagcagatggagcggggcttacgagg	CRISPR spacer
acgctttagcagatggagcggggcttacgaag	Protospacer
******************************.*

74. spacer 2.10|1174200|30|NC_012891|CRISPRCasFinder,CRT matches to MK448698 (Streptococcus phage Javan187, complete genome) position: , mismatch: 1, identity: 0.967

aatacaatctcatgattcgcaaacatcatg	CRISPR spacer
aatacaatctcatgattcgcaaacatcata	Protospacer
*****************************.

75. spacer 2.10|1174200|30|NC_012891|CRISPRCasFinder,CRT matches to MK448895 (Streptococcus phage Javan274, complete genome) position: , mismatch: 1, identity: 0.967

aatacaatctcatgattcgcaaacatcatg	CRISPR spacer
aatataatctcatgattcgcaaacatcatg	Protospacer
****.*************************

76. spacer 2.13|1174398|30|NC_012891|CRISPRCasFinder,CRT matches to NC_004584 (Streptococcus prophage 315.1, complete genome) position: , mismatch: 1, identity: 0.967

aagcatcatagtaaacatatctagcacgct	CRISPR spacer
aagcatcacagtaaacatatctagcacgct	Protospacer
********.*********************

77. spacer 2.13|1174398|30|NC_012891|CRISPRCasFinder,CRT matches to MK448978 (Streptococcus phage Javan532, complete genome) position: , mismatch: 1, identity: 0.967

aagcatcatagtaaacatatctagcacgct	CRISPR spacer
aagcatcacagtaaacatatctagcacgct	Protospacer
********.*********************

78. spacer 2.13|1174398|30|NC_012891|CRISPRCasFinder,CRT matches to MK448785 (Streptococcus phage Javan507, complete genome) position: , mismatch: 1, identity: 0.967

aagcatcatagtaaacatatctagcacgct	CRISPR spacer
aagcatcacagtaaacatatctagcacgct	Protospacer
********.*********************

79. spacer 3.2|1601618|37|NC_012891|PILER-CR matches to MK448681 (Streptococcus phage Javan141, complete genome) position: , mismatch: 1, identity: 0.973

gtcaactattttttctgtttttttgtatttttttctc	CRISPR spacer
gtcaactatttttcctgtttttttgtatttttttctc	Protospacer
*************.***********************

80. spacer 4.1|2067357|45|NC_012891|CRISPRCasFinder matches to MK448522 (Streptococcus satellite phage Javan519, complete genome) position: , mismatch: 1, identity: 0.978

ttttgcaaaatctatattaacgcaaataaatttggttgccaagat	CRISPR spacer
ttttgcaaaatctatattaacgcaaataaatttggttgtcaagat	Protospacer
**************************************.******

81. spacer 4.1|2067357|45|NC_012891|CRISPRCasFinder matches to MK448330 (Streptococcus satellite phage Javan136, complete genome) position: , mismatch: 1, identity: 0.978

ttttgcaaaatctatattaacgcaaataaatttggttgccaagat	CRISPR spacer
ttttgcaaaatctatattaacgcaaataaatttggttgtcaagat	Protospacer
**************************************.******

82. spacer 4.1|2067357|45|NC_012891|CRISPRCasFinder matches to MK448328 (Streptococcus satellite phage Javan130, complete genome) position: , mismatch: 1, identity: 0.978

ttttgcaaaatctatattaacgcaaataaatttggttgccaagat	CRISPR spacer
ttttgcaaaatctatattaacgcaaataaatttggttgtcaagat	Protospacer
**************************************.******

83. spacer 4.1|2067357|45|NC_012891|CRISPRCasFinder matches to MK448513 (Streptococcus satellite phage Javan479, complete genome) position: , mismatch: 1, identity: 0.978

ttttgcaaaatctatattaacgcaaataaatttggttgccaagat	CRISPR spacer
ttttgcaaaatctatattaacgcaaataaatttggttgtcaagat	Protospacer
**************************************.******

84. spacer 4.1|2067357|45|NC_012891|CRISPRCasFinder matches to MK448332 (Streptococcus satellite phage Javan142, complete genome) position: , mismatch: 1, identity: 0.978

ttttgcaaaatctatattaacgcaaataaatttggttgccaagat	CRISPR spacer
ttttgcaaaatctatattaacgcaaataaatttggttgtcaagat	Protospacer
**************************************.******

85. spacer 4.1|2067357|45|NC_012891|CRISPRCasFinder matches to MK448331 (Streptococcus satellite phage Javan138, complete genome) position: , mismatch: 1, identity: 0.978

ttttgcaaaatctatattaacgcaaataaatttggttgccaagat	CRISPR spacer
ttttgcaaaatctatattaacgcaaataaatttggttgtcaagat	Protospacer
**************************************.******

86. spacer 2.4|1173802|30|NC_012891|CRISPRCasFinder,CRT,PILER-CR matches to MK448946 (Streptococcus phage Javan456, complete genome) position: , mismatch: 2, identity: 0.933

aaaagtggctatcacgctgacacagactaa	CRISPR spacer
aaaagtggctgtcacgctgacacaggctaa	Protospacer
**********.**************.****

87. spacer 2.4|1173802|30|NC_012891|CRISPRCasFinder,CRT,PILER-CR matches to MK448775 (Streptococcus phage Javan489, complete genome) position: , mismatch: 2, identity: 0.933

aaaagtggctatcacgctgacacagactaa	CRISPR spacer
aaaagtggctgtcacgctgacacaggctaa	Protospacer
**********.**************.****

88. spacer 2.4|1173802|30|NC_012891|CRISPRCasFinder,CRT,PILER-CR matches to MK448794 (Streptococcus phage Javan525, complete genome) position: , mismatch: 2, identity: 0.933

aaaagtggctatcacgctgacacagactaa	CRISPR spacer
aaaagtggctgtcacgctgacacaggctaa	Protospacer
**********.**************.****

89. spacer 2.4|1173802|30|NC_012891|CRISPRCasFinder,CRT,PILER-CR matches to MK448955 (Streptococcus phage Javan478, complete genome) position: , mismatch: 2, identity: 0.933

aaaagtggctatcacgctgacacagactaa	CRISPR spacer
aaaagtggctgtcacgctgacacaggctaa	Protospacer
**********.**************.****

90. spacer 2.4|1173802|30|NC_012891|CRISPRCasFinder,CRT,PILER-CR matches to MK448763 (Streptococcus phage Javan451, complete genome) position: , mismatch: 2, identity: 0.933

aaaagtggctatcacgctgacacagactaa	CRISPR spacer
aaaagtggctgtcacgctgacacaggctaa	Protospacer
**********.**************.****

91. spacer 2.4|1173802|30|NC_012891|CRISPRCasFinder,CRT,PILER-CR matches to MK448953 (Streptococcus phage Javan474, complete genome) position: , mismatch: 2, identity: 0.933

aaaagtggctatcacgctgacacagactaa	CRISPR spacer
aaaagtggctgtcacgctgacacaggctaa	Protospacer
**********.**************.****

92. spacer 2.4|1173802|30|NC_012891|CRISPRCasFinder,CRT,PILER-CR matches to MK448944 (Streptococcus phage Javan452, complete genome) position: , mismatch: 2, identity: 0.933

aaaagtggctatcacgctgacacagactaa	CRISPR spacer
aaaagtggctgtcacgctgacacaggctaa	Protospacer
**********.**************.****

93. spacer 2.4|1173802|30|NC_012891|CRISPRCasFinder,CRT,PILER-CR matches to MK448772 (Streptococcus phage Javan483, complete genome) position: , mismatch: 2, identity: 0.933

aaaagtggctatcacgctgacacagactaa	CRISPR spacer
aaaagtggctgtcacgctgacacaggctaa	Protospacer
**********.**************.****

94. spacer 2.4|1173802|30|NC_012891|CRISPRCasFinder,CRT,PILER-CR matches to MK448962 (Streptococcus phage Javan496, complete genome) position: , mismatch: 2, identity: 0.933

aaaagtggctatcacgctgacacagactaa	CRISPR spacer
aaaagtggctgtcacgctgacacaggctaa	Protospacer
**********.**************.****

95. spacer 2.4|1173802|30|NC_012891|CRISPRCasFinder,CRT,PILER-CR matches to MK448958 (Streptococcus phage Javan486, complete genome) position: , mismatch: 2, identity: 0.933

aaaagtggctatcacgctgacacagactaa	CRISPR spacer
aaaagtggctgtcacgctgacacaggctaa	Protospacer
**********.**************.****

96. spacer 2.4|1173802|30|NC_012891|CRISPRCasFinder,CRT,PILER-CR matches to MK448951 (Streptococcus phage Javan470, complete genome) position: , mismatch: 2, identity: 0.933

aaaagtggctatcacgctgacacagactaa	CRISPR spacer
aaaagtggctgtcacgctgacacaggctaa	Protospacer
**********.**************.****

97. spacer 2.4|1173802|30|NC_012891|CRISPRCasFinder,CRT,PILER-CR matches to MK448793 (Streptococcus phage Javan523, complete genome) position: , mismatch: 2, identity: 0.933

aaaagtggctatcacgctgacacagactaa	CRISPR spacer
aaaagtggctgtcacgctgacacaggctaa	Protospacer
**********.**************.****

98. spacer 2.4|1173802|30|NC_012891|CRISPRCasFinder,CRT,PILER-CR matches to MK448765 (Streptococcus phage Javan459, complete genome) position: , mismatch: 2, identity: 0.933

aaaagtggctatcacgctgacacagactaa	CRISPR spacer
aaaagtggctgtcacgctgacacaggctaa	Protospacer
**********.**************.****

99. spacer 2.4|1173802|30|NC_012891|CRISPRCasFinder,CRT,PILER-CR matches to MK448954 (Streptococcus phage Javan476, complete genome) position: , mismatch: 2, identity: 0.933

aaaagtggctatcacgctgacacagactaa	CRISPR spacer
aaaagtggctgtcacgctgacacaggctaa	Protospacer
**********.**************.****

100. spacer 2.6|1173934|30|NC_012891|CRISPRCasFinder,CRT,PILER-CR matches to MK448859 (Streptococcus phage Javan170, complete genome) position: , mismatch: 2, identity: 0.933

gtcacgctgatatatgtcacccaaatatag	CRISPR spacer
gtcacactgatatatgttacccaaatatag	Protospacer
*****.***********.************

101. spacer 2.6|1173934|30|NC_012891|CRISPRCasFinder,CRT,PILER-CR matches to MK448688 (Streptococcus phage Javan161, complete genome) position: , mismatch: 2, identity: 0.933

gtcacgctgatatatgtcacccaaatatag	CRISPR spacer
gtcacactgatatatgttacccaaatatag	Protospacer
*****.***********.************

102. spacer 2.6|1173934|30|NC_012891|CRISPRCasFinder,CRT,PILER-CR matches to MK448683 (Streptococcus phage Javan149, complete genome) position: , mismatch: 2, identity: 0.933

gtcacgctgatatatgtcacccaaatatag	CRISPR spacer
gtcacgctgacatatgttacccaaatatag	Protospacer
**********.******.************

103. spacer 2.7|1174000|32|NC_012891|CRISPRCasFinder,CRT,PILER-CR matches to MK448795 (Streptococcus phage Javan527, complete genome) position: , mismatch: 2, identity: 0.938

acgctttagcagatggagcggggcttacgagg	CRISPR spacer
acgctttagcagatggagtggagcttacgagg	Protospacer
******************.**.**********

104. spacer 2.7|1174000|32|NC_012891|CRISPRCasFinder,CRT,PILER-CR matches to NC_028700 (Streptococcus phage T12, complete genome) position: , mismatch: 2, identity: 0.938

acgctttagcagatggagcggggcttacgagg	CRISPR spacer
acgctttagcagatggagtggagcttacgagg	Protospacer
******************.**.**********

105. spacer 2.7|1174000|32|NC_012891|CRISPRCasFinder,CRT,PILER-CR matches to MK448790 (Streptococcus phage Javan515, complete genome) position: , mismatch: 2, identity: 0.938

acgctttagcagatggagcggggcttacgagg	CRISPR spacer
acgctttagcagatggagtggagcttacgagg	Protospacer
******************.**.**********

106. spacer 2.7|1174000|32|NC_012891|CRISPRCasFinder,CRT,PILER-CR matches to MK448793 (Streptococcus phage Javan523, complete genome) position: , mismatch: 2, identity: 0.938

acgctttagcagatggagcggggcttacgagg	CRISPR spacer
acgctttagcagatggagtggagcttacgagg	Protospacer
******************.**.**********

107. spacer 2.7|1174000|32|NC_012891|CRISPRCasFinder,CRT,PILER-CR matches to MK448954 (Streptococcus phage Javan476, complete genome) position: , mismatch: 2, identity: 0.938

acgctttagcagatggagcggggcttacgagg	CRISPR spacer
acgctttagcagatggagtggagcttacgagg	Protospacer
******************.**.**********

108. spacer 2.7|1174000|32|NC_012891|CRISPRCasFinder,CRT,PILER-CR matches to MK448950 (Streptococcus phage Javan464, complete genome) position: , mismatch: 2, identity: 0.938

acgctttagcagatggagcggggcttacgagg	CRISPR spacer
acgctttagcagatggagtggagcttacgagg	Protospacer
******************.**.**********

109. spacer 2.9|1174134|30|NC_012891|CRISPRCasFinder,CRT matches to MK448775 (Streptococcus phage Javan489, complete genome) position: , mismatch: 2, identity: 0.933

agtattccagttctccatcaagtagttctc	CRISPR spacer
aatactccagttctccatcaagtagttctc	Protospacer
*.**.*************************

110. spacer 2.9|1174134|30|NC_012891|CRISPRCasFinder,CRT matches to MK448794 (Streptococcus phage Javan525, complete genome) position: , mismatch: 2, identity: 0.933

agtattccagttctccatcaagtagttctc	CRISPR spacer
aatactccagttctccatcaagtagttctc	Protospacer
*.**.*************************

111. spacer 2.9|1174134|30|NC_012891|CRISPRCasFinder,CRT matches to MK448763 (Streptococcus phage Javan451, complete genome) position: , mismatch: 2, identity: 0.933

agtattccagttctccatcaagtagttctc	CRISPR spacer
aatactccagttctccatcaagtagttctc	Protospacer
*.**.*************************

112. spacer 2.9|1174134|30|NC_012891|CRISPRCasFinder,CRT matches to MK448765 (Streptococcus phage Javan459, complete genome) position: , mismatch: 2, identity: 0.933

agtattccagttctccatcaagtagttctc	CRISPR spacer
aatactccagttctccatcaagtagttctc	Protospacer
*.**.*************************

113. spacer 2.13|1174398|30|NC_012891|CRISPRCasFinder,CRT matches to MK448860 (Streptococcus phage Javan172, complete genome) position: , mismatch: 2, identity: 0.933

aagcatcatagtaaacatatctagcacgct	CRISPR spacer
aagcgtcatagtaaacatacctagcacgct	Protospacer
****.**************.**********

114. spacer 2.1|1173604|30|NC_012891|CRISPRCasFinder,CRT matches to NC_009018 (Streptococcus phage phi3396, complete genome) position: , mismatch: 3, identity: 0.9

acagttaaatagctttggtatcttgtcgat	CRISPR spacer
acagttaaatagctttggtatcttgctgag	Protospacer
*************************..**

115. spacer 2.4|1173802|30|NC_012891|CRISPRCasFinder,CRT,PILER-CR matches to MK448852 (Streptococcus phage Javan140, complete genome) position: , mismatch: 3, identity: 0.9

aaaagtggctatcacgctgacacagactaa	CRISPR spacer
taaagtggcaattacgctgacacagactaa	Protospacer
 ******** **.*****************

116. spacer 2.10|1174200|30|NC_012891|CRISPRCasFinder,CRT matches to MK448818 (Streptococcus phage Javan597, complete genome) position: , mismatch: 3, identity: 0.9

aatacaatctcatgattcgcaaacatcatg	CRISPR spacer
aatgcaatctcacgattcgcaaacatcata	Protospacer
***.********.****************.

117. spacer 2.4|1173802|30|NC_012891|CRISPRCasFinder,CRT,PILER-CR matches to MK448779 (Streptococcus phage Javan497, complete genome) position: , mismatch: 4, identity: 0.867

aaaagtggctatcacgctgacacagactaa	CRISPR spacer
aaaagtggctgtcacgctgacacagccgca	Protospacer
**********.************** *  *

118. spacer 2.4|1173802|30|NC_012891|CRISPRCasFinder,CRT,PILER-CR matches to MK448968 (Streptococcus phage Javan512, complete genome) position: , mismatch: 4, identity: 0.867

aaaagtggctatcacgctgacacagactaa	CRISPR spacer
aaaagtggctgtcacgctgacacagccgca	Protospacer
**********.************** *  *

119. spacer 2.4|1173802|30|NC_012891|CRISPRCasFinder,CRT,PILER-CR matches to MK448864 (Streptococcus phage Javan180, complete genome) position: , mismatch: 4, identity: 0.867

aaaagtggctatcacgctgacacagactaa	CRISPR spacer
aaaagtggctatcacgctgacgcagccgca	Protospacer
*********************.*** *  *

120. spacer 2.4|1173802|30|NC_012891|CRISPRCasFinder,CRT,PILER-CR matches to MK448797 (Streptococcus phage Javan531, complete genome) position: , mismatch: 4, identity: 0.867

aaaagtggctatcacgctgacacagactaa	CRISPR spacer
aaaagtggctgtcacgctgacacagccgca	Protospacer
**********.************** *  *

121. spacer 2.4|1173802|30|NC_012891|CRISPRCasFinder,CRT,PILER-CR matches to NC_004589 (Streptococcus prophage 315.6, complete genome) position: , mismatch: 4, identity: 0.867

aaaagtggctatcacgctgacacagactaa	CRISPR spacer
aaaagtggctgtcacgctgacacagccgca	Protospacer
**********.************** *  *

122. spacer 2.11|1174266|30|NC_012891|CRISPRCasFinder,CRT matches to NZ_CP036355 (Bacillus sp. SYJ plasmid unnamed1, complete sequence) position: , mismatch: 4, identity: 0.867

-catattctattaatcctttatttaaaaaat	CRISPR spacer
ggata-tctattaatccttaattttaaaaat	Protospacer
  *** ************* **** ******

123. spacer 2.11|1174266|30|NC_012891|CRISPRCasFinder,CRT matches to CP008939 (Candidatus Caedibacter acanthamoebae plasmid Plasmid_00003, complete sequence) position: , mismatch: 4, identity: 0.867

-catattctattaatcctttatttaaaaaat	CRISPR spacer
agatagtct-ttaatcctttctttaaaaaat	Protospacer
  *** *** ********** **********

124. spacer 2.4|1173802|30|NC_012891|CRISPRCasFinder,CRT,PILER-CR matches to MK448933 (Streptococcus phage Javan420, complete genome) position: , mismatch: 5, identity: 0.833

aaaagtggctatcacgctgacacagactaa	CRISPR spacer
gaaagtcgctatcacgttgacacagaaaaa	Protospacer
.***** *********.*********  **

125. spacer 2.11|1174266|30|NC_012891|CRISPRCasFinder,CRT matches to NC_011412 (Clostridium perfringens plasmid pCP8533etx, complete sequence) position: , mismatch: 5, identity: 0.833

catattctattaatcctttatttaaaaaat	CRISPR spacer
taggttttattaatcctttatttataaaat	Protospacer
.* .**.***************** *****

126. spacer 2.11|1174266|30|NC_012891|CRISPRCasFinder,CRT matches to LR588166 (Pseudomonas phage vB_PaeM_MIJ3) position: , mismatch: 5, identity: 0.833

catattc-tattaatcctttatttaaaaaat	CRISPR spacer
-ttatgcatattaatcctttatataaaagat	Protospacer
  *** * ************** *****.**

127. spacer 2.3|1173736|30|NC_012891|CRISPRCasFinder,CRT,PILER-CR matches to MK448925 (Streptococcus phage Javan386, complete genome) position: , mismatch: 6, identity: 0.8

gccttaggaaacaaagcatttacactacca	CRISPR spacer
tgctttggaaacaaagcattgacactgaca	Protospacer
  *** ************** *****. **

128. spacer 2.8|1174068|30|NC_012891|CRISPRCasFinder,CRT matches to MN693492 (Marine virus AFVG_25M361, complete genome) position: , mismatch: 6, identity: 0.8

gcaaaagctttctcatattttactcgattc---	CRISPR spacer
gcaagagctttctcatattt---ttgaatcatt	Protospacer
****.***************   *.** **

129. spacer 2.11|1174266|30|NC_012891|CRISPRCasFinder,CRT matches to MT080586 (UNVERIFIED: Staphylococcus phage vB_SauM_EW2, complete genome) position: , mismatch: 6, identity: 0.8

catattctattaatcctttatttaaaaaat	CRISPR spacer
aatattttatttatcctttatttaccatat	Protospacer
 *****.**** ************  * **

130. spacer 2.11|1174266|30|NC_012891|CRISPRCasFinder,CRT matches to MT080594 (UNVERIFIED: Staphylococcus phage vB_SauM_EW4, complete genome) position: , mismatch: 6, identity: 0.8

catattctattaatcctttatttaaaaaat	CRISPR spacer
aatattttatttatcctttatttaccatat	Protospacer
 *****.**** ************  * **

131. spacer 2.11|1174266|30|NC_012891|CRISPRCasFinder,CRT matches to MT080582 (UNVERIFIED: Staphylococcus phage vB_SauM_EW1, complete genome) position: , mismatch: 6, identity: 0.8

catattctattaatcctttatttaaaaaat	CRISPR spacer
aatattttatttatcctttatttaccatat	Protospacer
 *****.**** ************  * **

132. spacer 2.11|1174266|30|NC_012891|CRISPRCasFinder,CRT matches to AP013721 (Uncultured Mediterranean phage uvMED isolate uvMED-CGF-C22A-MedDCM-OCT-S45-C35, *** SEQUENCING IN PROGRESS ***) position: , mismatch: 6, identity: 0.8

catattctattaatcctttatttaaaaaat	CRISPR spacer
tagattgttttaatcctttatttaaagatt	Protospacer
.* *** * *****************.* *

133. spacer 2.11|1174266|30|NC_012891|CRISPRCasFinder,CRT matches to AP014427 (Uncultured Mediterranean phage uvMED isolate uvMED-CGF-C22-MedDCM-OCT-S28-C14, *** SEQUENCING IN PROGRESS ***, 3 ordered pieces) position: , mismatch: 6, identity: 0.8

catattctattaatcctttatttaaaaaat	CRISPR spacer
tagattgttttaatcctttatttaaagatt	Protospacer
.* *** * *****************.* *

134. spacer 2.11|1174266|30|NC_012891|CRISPRCasFinder,CRT matches to MK448860 (Streptococcus phage Javan172, complete genome) position: , mismatch: 6, identity: 0.8

catattctattaatcctttatttaaaaaat	CRISPR spacer
ctaaatcaattaatccttgatttaaaaagt	Protospacer
*  * ** ********** *********.*

135. spacer 2.11|1174266|30|NC_012891|CRISPRCasFinder,CRT matches to NZ_CP036355 (Bacillus sp. SYJ plasmid unnamed1, complete sequence) position: , mismatch: 7, identity: 0.767

catattcta----ttaatcctttatttaaaaaat	CRISPR spacer
----tttcaagctttaatcttttatttaaaaaat	Protospacer
    **..*    ******.**************

136. spacer 2.11|1174266|30|NC_012891|CRISPRCasFinder,CRT matches to MT074137 (Bacteroides phage DAC16, complete genome) position: , mismatch: 7, identity: 0.767

catattctattaatcctttatttaaaaaat	CRISPR spacer
gtggttctattaatcctaaatttaaaaatt	Protospacer
   .*************  ********* *

137. spacer 2.11|1174266|30|NC_012891|CRISPRCasFinder,CRT matches to MT074142 (Bacteroides phage DAC23, complete genome) position: , mismatch: 7, identity: 0.767

catattctattaatcctttatttaaaaaat	CRISPR spacer
gtggttctattaatcctaaatttaaaaatt	Protospacer
   .*************  ********* *

138. spacer 2.11|1174266|30|NC_012891|CRISPRCasFinder,CRT matches to MT074141 (Bacteroides phage DAC22, complete genome) position: , mismatch: 7, identity: 0.767

catattctattaatcctttatttaaaaaat	CRISPR spacer
gtggttctattaatcctaaatttaaaaatt	Protospacer
   .*************  ********* *

139. spacer 2.11|1174266|30|NC_012891|CRISPRCasFinder,CRT matches to MN692988 (Marine virus AFVG_117M76, complete genome) position: , mismatch: 7, identity: 0.767

catattctattaatcctttatttaaaaaat	CRISPR spacer
tgtattcttttattcctttatttaaatttt	Protospacer
..****** *** *************   *

140. spacer 2.11|1174266|30|NC_012891|CRISPRCasFinder,CRT matches to MT074146 (Bacteroides phage SJC03, complete genome) position: , mismatch: 7, identity: 0.767

catattctattaatcctttatttaaaaaat	CRISPR spacer
gtggttctattaatcctaaatttaaaaatt	Protospacer
   .*************  ********* *

141. spacer 2.11|1174266|30|NC_012891|CRISPRCasFinder,CRT matches to MT074139 (Bacteroides phage DAC19, complete genome) position: , mismatch: 7, identity: 0.767

catattctattaatcctttatttaaaaaat	CRISPR spacer
gtggttctattaatcctaaatttaaaaatt	Protospacer
   .*************  ********* *

142. spacer 2.11|1174266|30|NC_012891|CRISPRCasFinder,CRT matches to MT074140 (Bacteroides phage DAC20, complete genome) position: , mismatch: 7, identity: 0.767

catattctattaatcctttatttaaaaaat	CRISPR spacer
gtggttctattaatcctaaatttaaaaatt	Protospacer
   .*************  ********* *

143. spacer 2.11|1174266|30|NC_012891|CRISPRCasFinder,CRT matches to NZ_KY303941 (Enterococcus faecalis strain 3 plasmid pGTC3, complete sequence) position: , mismatch: 7, identity: 0.767

catattctattaatcctttatttaaaaaat	CRISPR spacer
taaaatctattaatcctttatttcaaagta	Protospacer
.* * ****************** ***.

144. spacer 2.11|1174266|30|NC_012891|CRISPRCasFinder,CRT matches to NZ_KT897276 (Clostridium botulinum strain INGR16-02E1 plasmid pINGR16-02E1, complete sequence) position: , mismatch: 7, identity: 0.767

catattctattaatcctttatttaaaaaat	CRISPR spacer
atgatgtttttaatcctttatttacaaaat	Protospacer
   ** .* *************** *****

145. spacer 2.11|1174266|30|NC_012891|CRISPRCasFinder,CRT matches to NZ_KT897280 (Clostridium botulinum strain FI1111E1 plasmid pFI1111E1, complete sequence) position: , mismatch: 7, identity: 0.767

catattctattaatcctttatttaaaaaat	CRISPR spacer
atgatgtttttaatcctttatttacaaaat	Protospacer
   ** .* *************** *****

146. spacer 2.11|1174266|30|NC_012891|CRISPRCasFinder,CRT matches to NZ_KT897275 (Clostridium botulinum strain IFR 12/29 plasmid p12/29, complete sequence) position: , mismatch: 7, identity: 0.767

catattctattaatcctttatttaaaaaat	CRISPR spacer
atgatgtttttaatcctttatttacaaaat	Protospacer
   ** .* *************** *****

147. spacer 2.11|1174266|30|NC_012891|CRISPRCasFinder,CRT matches to NZ_KT897277 (Clostridium botulinum strain ST0210E1 plasmid pST0210E1, complete sequence) position: , mismatch: 7, identity: 0.767

catattctattaatcctttatttaaaaaat	CRISPR spacer
atgatgtttttaatcctttatttacaaaat	Protospacer
   ** .* *************** *****

148. spacer 2.11|1174266|30|NC_012891|CRISPRCasFinder,CRT matches to NZ_KT897278 (Clostridium botulinum strain FWSKR40E1 plasmid pFWSKR40E1, complete sequence) position: , mismatch: 7, identity: 0.767

catattctattaatcctttatttaaaaaat	CRISPR spacer
atgatgtttttaatcctttatttacaaaat	Protospacer
   ** .* *************** *****

149. spacer 2.11|1174266|30|NC_012891|CRISPRCasFinder,CRT matches to NZ_KT897279 (Clostridium botulinum strain SWKR38E2 plasmid pSWKR38E2, complete sequence) position: , mismatch: 7, identity: 0.767

catattctattaatcctttatttaaaaaat	CRISPR spacer
atgatgtttttaatcctttatttacaaaat	Protospacer
   ** .* *************** *****

150. spacer 2.11|1174266|30|NC_012891|CRISPRCasFinder,CRT matches to NC_011973 (Bacillus cereus Q1 plasmid pBc239, complete sequence) position: , mismatch: 7, identity: 0.767

catattcta----ttaatcctttatttaaaaaat	CRISPR spacer
----tttcaagctttaatcttttatttaaaaaat	Protospacer
    **..*    ******.**************

151. spacer 2.11|1174266|30|NC_012891|CRISPRCasFinder,CRT matches to NC_011777 (Bacillus cereus AH820 plasmid pAH820_272, complete sequence) position: , mismatch: 7, identity: 0.767

catattcta----ttaatcctttatttaaaaaat	CRISPR spacer
----tttcaagctttaatcttttatttaaaaaat	Protospacer
    **..*    ******.**************

152. spacer 2.11|1174266|30|NC_012891|CRISPRCasFinder,CRT matches to NZ_CP017256 (Clostridium taeniosporum strain 1/k plasmid pCt3, complete sequence) position: , mismatch: 7, identity: 0.767

catattctattaatcctttatttaaaaaat	CRISPR spacer
aaaattctattaattctttatttactttat	Protospacer
 * ***********.*********    **

153. spacer 2.11|1174266|30|NC_012891|CRISPRCasFinder,CRT matches to NZ_CP047086 (Bacillus paranthracis strain BC307 plasmid pCE1, complete sequence) position: , mismatch: 7, identity: 0.767

catattcta----ttaatcctttatttaaaaaat	CRISPR spacer
----tttcaagctttaatcttttatttaaaaaat	Protospacer
    **..*    ******.**************

154. spacer 2.11|1174266|30|NC_012891|CRISPRCasFinder,CRT matches to NZ_CP022346 (Bacillus thuringiensis strain c25 plasmid unnamed1, complete sequence) position: , mismatch: 7, identity: 0.767

catattcta----ttaatcctttatttaaaaaat	CRISPR spacer
----tttcaagctttaatcttttatttaaaaaat	Protospacer
    **..*    ******.**************

155. spacer 2.11|1174266|30|NC_012891|CRISPRCasFinder,CRT matches to MT774385 (CrAssphage cr108_1, complete genome) position: , mismatch: 7, identity: 0.767

catattctattaatcctttatttaaaaaat	CRISPR spacer
catattctattaatcctgtatatgatgtag	Protospacer
***************** *** *.* . *

156. spacer 2.14|1174464|30|NC_012891|CRISPRCasFinder,CRT,PILER-CR matches to FR682616 (Roseovarius sp. 217 phage 1 partial genome sequence) position: , mismatch: 7, identity: 0.767

atgctcaaaaagatgtgctgtccaacagta	CRISPR spacer
atgctcagaaagatgtactgtcctatcatc	Protospacer
*******.********.****** *. .*

157. spacer 2.14|1174464|30|NC_012891|CRISPRCasFinder,CRT,PILER-CR matches to FR719956 (Roseovarius Plymouth Podovirus 1 partial sequence) position: , mismatch: 7, identity: 0.767

atgctcaaaaagatgtgctgtccaacagta	CRISPR spacer
atgctcagaaagatgtactgtcctatcatc	Protospacer
*******.********.****** *. .*

158. spacer 2.16|1174596|30|NC_012891|CRISPRCasFinder,CRT,PILER-CR matches to NC_019763 (Oscillatoria nigro-viridis PCC 7112 plasmid pOSC7112.01, complete sequence) position: , mismatch: 7, identity: 0.767

atggtacaagtaaaactaccgccccagtta	CRISPR spacer
ctagtacaaacaaaactaccgccccagaac	Protospacer
 *.******..****************

159. spacer 3.1|1601548|33|NC_012891|PILER-CR matches to FR671407 (Streptococcus phage 34117) position: , mismatch: 7, identity: 0.788

aagcttttgtttccttaagcttgattttattat	CRISPR spacer
tttttgttatttccttaagcttgattatattat	Protospacer
   .* **.***************** ******

160. spacer 3.1|1601548|33|NC_012891|PILER-CR matches to MK044828 (Streptococcus phage 33888, complete genome) position: , mismatch: 7, identity: 0.788

aagcttttgtttccttaagcttgattttattat	CRISPR spacer
tttttgttatttccttaagcttgattatattat	Protospacer
   .* **.***************** ******

161. spacer 3.1|1601548|33|NC_012891|PILER-CR matches to KT337344 (Streptococcus phage phiARI0274b, partial genome) position: , mismatch: 7, identity: 0.788

aagcttttgtttccttaagcttgattttattat	CRISPR spacer
tttttgttatttccttaagcttgatttaattat	Protospacer
   .* **.****************** *****

162. spacer 3.1|1601548|33|NC_012891|PILER-CR matches to NC_031929 (Streptococcus phage phiARI0468-1, complete genome) position: , mismatch: 7, identity: 0.788

aagcttttgtttccttaagcttgattttattat	CRISPR spacer
tttttgttatttccttaagcttgattatattat	Protospacer
   .* **.***************** ******

163. spacer 3.1|1601548|33|NC_012891|PILER-CR matches to FR671410 (Streptococcus phage 8140) position: , mismatch: 7, identity: 0.788

aagcttttgtttccttaagcttgattttattat	CRISPR spacer
tttttgttatttccttaagcttgattatattat	Protospacer
   .* **.***************** ******

164. spacer 3.1|1601548|33|NC_012891|PILER-CR matches to KT337345 (Streptococcus phage phiARI0285-1, partial genome) position: , mismatch: 7, identity: 0.788

aagcttttgtttccttaagcttgattttattat	CRISPR spacer
tttttgttatttccttaagcttgattatattat	Protospacer
   .* **.***************** ******

165. spacer 3.1|1601548|33|NC_012891|PILER-CR matches to NC_024370 (Streptococcus phage IC1, complete sequence) position: , mismatch: 7, identity: 0.788

aagcttttgtttccttaagcttgattttattat	CRISPR spacer
tttttgttatttccttaagcttgatttaattat	Protospacer
   .* **.****************** *****

166. spacer 3.1|1601548|33|NC_012891|PILER-CR matches to NC_024357 (Streptococcus phage K13, complete sequence) position: , mismatch: 7, identity: 0.788

aagcttttgtttccttaagcttgattttattat	CRISPR spacer
tttttgttatttccttaagcttgattatattat	Protospacer
   .* **.***************** ******

167. spacer 3.1|1601548|33|NC_012891|PILER-CR matches to NC_031920 (Streptococcus phage phiARI0004, complete genome) position: , mismatch: 7, identity: 0.788

aagcttttgtttccttaagcttgattttattat	CRISPR spacer
tttttgttatttccttaagcttgatttaattat	Protospacer
   .* **.****************** *****

168. spacer 3.1|1601548|33|NC_012891|PILER-CR matches to FR671411 (Streptococcus phage 2167) position: , mismatch: 7, identity: 0.788

aagcttttgtttccttaagcttgattttattat	CRISPR spacer
ggtttgttatttccttaagcttgattatattat	Protospacer
.. .* **.***************** ******

169. spacer 3.1|1601548|33|NC_012891|PILER-CR matches to KT337362 (Streptococcus phage phiARI0598b, partial genome) position: , mismatch: 7, identity: 0.788

aagcttttgtttccttaagcttgattttattat	CRISPR spacer
tttttgttatttccttaagcttgatttaattat	Protospacer
   .* **.****************** *****

170. spacer 3.1|1601548|33|NC_012891|PILER-CR matches to KT337340 (Streptococcus phage phiARI0031, complete genome) position: , mismatch: 7, identity: 0.788

aagcttttgtttccttaagcttgattttattat	CRISPR spacer
tttttgttatttccttaagcttgatttaattat	Protospacer
   .* **.****************** *****

171. spacer 3.1|1601548|33|NC_012891|PILER-CR matches to KT337342 (Streptococcus phage phiARI0131-2, complete genome) position: , mismatch: 7, identity: 0.788

aagcttttgtttccttaagcttgattttattat	CRISPR spacer
tttttgttatttccttaagcttgatttaattat	Protospacer
   .* **.****************** *****

172. spacer 3.1|1601548|33|NC_012891|PILER-CR matches to MK448917 (Streptococcus phage Javan362, complete genome) position: , mismatch: 7, identity: 0.788

aagcttttgtttccttaagcttgattttattat	CRISPR spacer
gctttgttatttccttaagcttgatttaattat	Protospacer
.  .* **.****************** *****

173. spacer 3.1|1601548|33|NC_012891|PILER-CR matches to KY065457 (Streptococcus phage IPP16, complete genome) position: , mismatch: 7, identity: 0.788

aagcttttgtttccttaagcttgattttattat	CRISPR spacer
gttttattatttccttaagcttgatttaattat	Protospacer
.  .* **.****************** *****

174. spacer 3.1|1601548|33|NC_012891|PILER-CR matches to MK448891 (Streptococcus phage Javan266, complete genome) position: , mismatch: 7, identity: 0.788

aagcttttgtttccttaagcttgattttattat	CRISPR spacer
gttttgttatttccttaagcttgattatattat	Protospacer
.  .* **.***************** ******

175. spacer 3.1|1601548|33|NC_012891|PILER-CR matches to KY065486 (Streptococcus phage IPP46, complete genome) position: , mismatch: 7, identity: 0.788

aagcttttgtttccttaagcttgattttattat	CRISPR spacer
ggtttgttatttccttaagcttgattatattat	Protospacer
.. .* **.***************** ******

176. spacer 3.1|1601548|33|NC_012891|PILER-CR matches to MK448740 (Streptococcus phage Javan367, complete genome) position: , mismatch: 7, identity: 0.788

aagcttttgtttccttaagcttgattttattat	CRISPR spacer
tttttgttatttccttaagcttgatttaattat	Protospacer
   .* **.****************** *****

177. spacer 3.1|1601548|33|NC_012891|PILER-CR matches to KY065500 (Streptococcus phage IPP64, complete genome) position: , mismatch: 7, identity: 0.788

aagcttttgtttccttaagcttgattttattat	CRISPR spacer
ggtttgttatttccttaagcttgattatattat	Protospacer
.. .* **.***************** ******

178. spacer 3.1|1601548|33|NC_012891|PILER-CR matches to MK448910 (Streptococcus phage Javan336, complete genome) position: , mismatch: 7, identity: 0.788

aagcttttgtttccttaagcttgattttattat	CRISPR spacer
tttttgttatttccttaagcttgatttaattat	Protospacer
   .* **.****************** *****

179. spacer 3.1|1601548|33|NC_012891|PILER-CR matches to KY065449 (Streptococcus phage IPP5, complete genome) position: , mismatch: 7, identity: 0.788

aagcttttgtttccttaagcttgattttattat	CRISPR spacer
tttttgttatttccttaagcttgatttaattat	Protospacer
   .* **.****************** *****

180. spacer 3.1|1601548|33|NC_012891|PILER-CR matches to NC_010945 (Streptococcus phage PH15, complete genome) position: , mismatch: 7, identity: 0.788

aagcttttgtttccttaagcttgattttattat	CRISPR spacer
atgatcgttttttcttaagcttgatttaattat	Protospacer
* * *. * ***.************** *****

181. spacer 2.3|1173736|30|NC_012891|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP053970 (Bacillus thuringiensis strain FDAARGOS_796 plasmid unnamed2, complete sequence) position: , mismatch: 8, identity: 0.733

gccttaggaaacaaagcatttacactacca	CRISPR spacer
ggaagaggtaagaaagcatttacactactg	Protospacer
*    *** ** ****************..

182. spacer 2.3|1173736|30|NC_012891|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP053979 (Bacillus thuringiensis strain FDAARGOS_795 plasmid unnamed3, complete sequence) position: , mismatch: 8, identity: 0.733

gccttaggaaacaaagcatttacactacca	CRISPR spacer
ggaagaggtaagaaagcatttacactactg	Protospacer
*    *** ** ****************..

183. spacer 2.3|1173736|30|NC_012891|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP013277 (Bacillus thuringiensis serovar israelensis strain AM65-52 plasmid pAM65-52-2-350K, complete sequence) position: , mismatch: 8, identity: 0.733

gccttaggaaacaaagcatttacactacca	CRISPR spacer
ggaagaggtaagaaagcatttacactactg	Protospacer
*    *** ** ****************..

184. spacer 2.3|1173736|30|NC_012891|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP039723 (Bacillus thuringiensis strain BT-59 plasmid p2, complete sequence) position: , mismatch: 8, identity: 0.733

gccttaggaaacaaagcatttacactacca	CRISPR spacer
ggaagaggtaagaaagcatttacactactg	Protospacer
*    *** ** ****************..

185. spacer 2.3|1173736|30|NC_012891|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP009348 (Bacillus thuringiensis HD1002 plasmid 2, complete sequence) position: , mismatch: 8, identity: 0.733

gccttaggaaacaaagcatttacactacca	CRISPR spacer
ggaagaggtaagaaagcatttacactactg	Protospacer
*    *** ** ****************..

186. spacer 2.3|1173736|30|NC_012891|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP045024 (Bacillus thuringiensis strain JW-1 plasmid p2, complete sequence) position: , mismatch: 8, identity: 0.733

gccttaggaaacaaagcatttacactacca	CRISPR spacer
ggaagaggtaagaaagcatttacactactg	Protospacer
*    *** ** ****************..

187. spacer 2.3|1173736|30|NC_012891|CRISPRCasFinder,CRT,PILER-CR matches to NC_018516 (Bacillus thuringiensis HD-789 plasmid pBTHD789-1, complete sequence) position: , mismatch: 8, identity: 0.733

gccttaggaaacaaagcatttacactacca	CRISPR spacer
ggaagaggtaagaaagcatttacactactg	Protospacer
*    *** ** ****************..

188. spacer 2.3|1173736|30|NC_012891|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP009334 (Bacillus thuringiensis strain HD1011 plasmid 2, complete sequence) position: , mismatch: 8, identity: 0.733

gccttaggaaacaaagcatttacactacca	CRISPR spacer
ggaagaggtaagaaagcatttacactactg	Protospacer
*    *** ** ****************..

189. spacer 2.4|1173802|30|NC_012891|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP014308 (Burkholderia sp. PAMC 26561 plasmid unnamed1, complete sequence) position: , mismatch: 8, identity: 0.733

aaaagtggctatcacgctgacacagactaa	CRISPR spacer
attcgtggcaatgacgctgacacagacggc	Protospacer
*   ***** ** ************** .

190. spacer 2.4|1173802|30|NC_012891|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP014309 (Burkholderia sp. PAMC 26561 plasmid unnamed2, complete sequence) position: , mismatch: 8, identity: 0.733

aaaagtggctatcacgctgacacagactaa	CRISPR spacer
attcgtggcaatgacgctgacacagacggc	Protospacer
*   ***** ** ************** .

191. spacer 2.9|1174134|30|NC_012891|CRISPRCasFinder,CRT matches to NZ_CP015006 (Aminobacter aminovorans strain KCTC 2477 plasmid pAA01, complete sequence) position: , mismatch: 8, identity: 0.733

agtattccagttctccatcaagtagttctc	CRISPR spacer
atgcgcccagttctccatcaggtagttcca	Protospacer
*    .**************.*******.

192. spacer 2.11|1174266|30|NC_012891|CRISPRCasFinder,CRT matches to NZ_LR214986 (Mycoplasma cynos strain NCTC10142 plasmid 13) position: , mismatch: 8, identity: 0.733

catattctattaatcctttatttaaaaaat	CRISPR spacer
caacaaatattaatccattatttaaaaata	Protospacer
**     ********* ***********

193. spacer 2.11|1174266|30|NC_012891|CRISPRCasFinder,CRT matches to MH319743 (Marine virus AG-345-E15 Ga0172270_13 genomic sequence) position: , mismatch: 8, identity: 0.733

catattctattaatcctttatttaaaaaat	CRISPR spacer
ttaaatcttttaatcctttatttaaagtac	Protospacer
.  * *** *****************. *.

194. spacer 2.15|1174530|30|NC_012891|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP030933 (Enterococcus gilvus strain CR1 plasmid pCR1A, complete sequence) position: , mismatch: 8, identity: 0.733

aaagacggtttttactttcaaaaatgagat	CRISPR spacer
tgaagggttttttattttcaaaaatgagag	Protospacer
 .*.. * ******.**************

195. spacer 2.15|1174530|30|NC_012891|CRISPRCasFinder,CRT,PILER-CR matches to NC_028969 (Brevibacillus phage Osiris, complete genome) position: , mismatch: 8, identity: 0.733

aaagacggtttttactttcaaaaatgagat	CRISPR spacer
ataactcctttttactttcaaaaattagag	Protospacer
* *. .  ***************** ***

196. spacer 2.15|1174530|30|NC_012891|CRISPRCasFinder,CRT,PILER-CR matches to NC_041976 (Brevibacillus phage Jimmer2, complete genome) position: , mismatch: 8, identity: 0.733

aaagacggtttttactttcaaaaatgagat	CRISPR spacer
ataactcctttttactttcaaaaattagag	Protospacer
* *. .  ***************** ***

197. spacer 2.15|1174530|30|NC_012891|CRISPRCasFinder,CRT,PILER-CR matches to KT151958 (Brevibacillus phage Powder, complete genome) position: , mismatch: 8, identity: 0.733

aaagacggtttttactttcaaaaatgagat	CRISPR spacer
ataactcctttttactttcaaaaattagag	Protospacer
* *. .  ***************** ***

198. spacer 2.15|1174530|30|NC_012891|CRISPRCasFinder,CRT,PILER-CR matches to KC595515 (Brevibacillus phage Jimmer1, complete genome) position: , mismatch: 8, identity: 0.733

aaagacggtttttactttcaaaaatgagat	CRISPR spacer
ataactcctttttactttcaaaaattagag	Protospacer
* *. .  ***************** ***

199. spacer 2.16|1174596|30|NC_012891|CRISPRCasFinder,CRT,PILER-CR matches to NC_019679 (Rivularia sp. PCC 7116 plasmid pRIV7116.01, complete sequence) position: , mismatch: 8, identity: 0.733

atggtacaagtaaaactaccgccccagtta	CRISPR spacer
atggtacaactaaaaccaccgccagtagca	Protospacer
********* ******.******   . .*

200. spacer 3.1|1601548|33|NC_012891|PILER-CR matches to KT337341 (Streptococcus phage phiARI0131-1, complete genome) position: , mismatch: 8, identity: 0.758

aagcttttgtttccttaagcttgattttattat	CRISPR spacer
ttacctccttttccttaagcttgatttaattat	Protospacer
  .*.*.. ****************** *****

201. spacer 3.1|1601548|33|NC_012891|PILER-CR matches to KT337352 (Streptococcus phage phiARI0460-1, complete genome) position: , mismatch: 8, identity: 0.758

aagcttttgtttccttaagcttgattttattat	CRISPR spacer
ttacctccttttccttaagcttgatttaattat	Protospacer
  .*.*.. ****************** *****

202. spacer 3.1|1601548|33|NC_012891|PILER-CR matches to FR671406 (Streptococcus phage 040922) position: , mismatch: 8, identity: 0.758

aagcttttgtttccttaagcttgattttattat	CRISPR spacer
ttacctccttttccttaagcttgatttaattat	Protospacer
  .*.*.. ****************** *****

203. spacer 3.1|1601548|33|NC_012891|PILER-CR matches to MK044829 (Streptococcus phage 109751, complete genome) position: , mismatch: 8, identity: 0.758

aagcttttgtttccttaagcttgattttattat	CRISPR spacer
ttacctccttttccttaagcttgatttaattat	Protospacer
  .*.*.. ****************** *****

204. spacer 3.1|1601548|33|NC_012891|PILER-CR matches to KY065480 (Streptococcus phage IPP40, complete genome) position: , mismatch: 8, identity: 0.758

aagcttttgtttccttaagcttgattttattat	CRISPR spacer
ttacctccttttccttaagcttgatttaattat	Protospacer
  .*.*.. ****************** *****

205. spacer 3.1|1601548|33|NC_012891|PILER-CR matches to KY065478 (Streptococcus phage IPP38, complete genome) position: , mismatch: 8, identity: 0.758

aagcttttgtttccttaagcttgattttattat	CRISPR spacer
ttacctccttttccttaagcttgatttaattat	Protospacer
  .*.*.. ****************** *****

206. spacer 3.1|1601548|33|NC_012891|PILER-CR matches to KY065497 (Streptococcus phage IPP61, complete genome) position: , mismatch: 8, identity: 0.758

aagcttttgtttccttaagcttgattttattat	CRISPR spacer
ttacctccttttccttaagcttgatttaattat	Protospacer
  .*.*.. ****************** *****

207. spacer 3.1|1601548|33|NC_012891|PILER-CR matches to KY065451 (Streptococcus phage IPP9, complete genome) position: , mismatch: 8, identity: 0.758

aagcttttgtttccttaagcttgattttattat	CRISPR spacer
ttacctccttttccttaagcttgatttaattat	Protospacer
  .*.*.. ****************** *****

208. spacer 3.1|1601548|33|NC_012891|PILER-CR matches to KY065488 (Streptococcus phage IPP50, complete genome) position: , mismatch: 8, identity: 0.758

aagcttttgtttccttaagcttgattttattat	CRISPR spacer
ttacctccttttccttaagcttgatttaattat	Protospacer
  .*.*.. ****************** *****

209. spacer 3.1|1601548|33|NC_012891|PILER-CR matches to KJ417497 (Streptococcus phage Spn1, complete genome) position: , mismatch: 8, identity: 0.758

aagcttttgtttccttaagcttgattttattat	CRISPR spacer
ttacctccttttccttaagcttgatttaattat	Protospacer
  .*.*.. ****************** *****

210. spacer 3.1|1601548|33|NC_012891|PILER-CR matches to KY065467 (Streptococcus phage IPP26, complete genome) position: , mismatch: 8, identity: 0.758

aagcttttgtttccttaagcttgattttattat	CRISPR spacer
ttacctccttttccttaagcttgatttaattat	Protospacer
  .*.*.. ****************** *****

211. spacer 2.14|1174464|30|NC_012891|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP009975 (Pseudomonas putida S12 plasmid pTTS12, complete sequence) position: , mismatch: 9, identity: 0.7

atgctcaaaaagatgtgctgtccaacagta	CRISPR spacer
ctgctcaaaatgatgttctgtccatggagg	Protospacer
 ********* ***** *******  .. .

212. spacer 2.14|1174464|30|NC_012891|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP040126 (Pseudomonas aeruginosa strain PA298 plasmid pBM908, complete sequence) position: , mismatch: 9, identity: 0.7

atgctcaaaaagatgtgctgtccaacagta	CRISPR spacer
ctgctcaaaatgatgttctgtccatggagg	Protospacer
 ********* ***** *******  .. .

213. spacer 2.14|1174464|30|NC_012891|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP016215 (Pseudomonas aeruginosa strain PA121617 plasmid pBM413, complete sequence) position: , mismatch: 9, identity: 0.7

atgctcaaaaagatgtgctgtccaacagta	CRISPR spacer
ctgctcaaaatgatgttctgtccatggagg	Protospacer
 ********* ***** *******  .. .

214. spacer 2.14|1174464|30|NC_012891|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP029096 (Pseudomonas aeruginosa strain AR439 plasmid unnamed2, complete sequence) position: , mismatch: 9, identity: 0.7

atgctcaaaaagatgtgctgtccaacagta	CRISPR spacer
ctgctcaaaatgatgttctgtccatggagg	Protospacer
 ********* ***** *******  .. .

215. spacer 2.14|1174464|30|NC_012891|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP045917 (Pseudomonas aeruginosa strain CF39S plasmid pCF39S, complete sequence) position: , mismatch: 9, identity: 0.7

atgctcaaaaagatgtgctgtccaacagta	CRISPR spacer
ctgctcaaaatgatgttctgtccatggagg	Protospacer
 ********* ***** *******  .. .

216. spacer 2.14|1174464|30|NC_012891|CRISPRCasFinder,CRT,PILER-CR matches to CP003983 (Candidatus Tremblaya phenacola PAVE plasmid, complete sequence) position: , mismatch: 9, identity: 0.7

atgctcaaaaagatgtgctgtccaacagta	CRISPR spacer
caaatcaaagagatttgctgtccaacatct	Protospacer
  . *****.**** ************ .

217. spacer 2.14|1174464|30|NC_012891|CRISPRCasFinder,CRT,PILER-CR matches to MF344571 (Pseudomonas aeruginosa plasmid pR31014-IMP, complete sequence) position: , mismatch: 9, identity: 0.7

atgctcaaaaagatgtgctgtccaacagta	CRISPR spacer
ctgctcaaaatgatgttctgtccatggagg	Protospacer
 ********* ***** *******  .. .

218. spacer 2.14|1174464|30|NC_012891|CRISPRCasFinder,CRT,PILER-CR matches to MF344568 (Pseudomonas aeruginosa plasmid p727-IMP, complete sequence) position: , mismatch: 9, identity: 0.7

atgctcaaaaagatgtgctgtccaacagta	CRISPR spacer
ctgctcaaaatgatgttctgtccatggagg	Protospacer
 ********* ***** *******  .. .

219. spacer 2.14|1174464|30|NC_012891|CRISPRCasFinder,CRT,PILER-CR matches to MF344570 (Pseudomonas aeruginosa plasmid pA681-IMP, complete sequence) position: , mismatch: 9, identity: 0.7

atgctcaaaaagatgtgctgtccaacagta	CRISPR spacer
ctgctcaaaatgatgttctgtccatggagg	Protospacer
 ********* ***** *******  .. .

220. spacer 2.14|1174464|30|NC_012891|CRISPRCasFinder,CRT,PILER-CR matches to CP027478 (Pseudomonas koreensis strain P19E3 plasmid p1, complete sequence) position: , mismatch: 9, identity: 0.7

atgctcaaaaagatgtgctgtccaacagta	CRISPR spacer
ctgctcaaaatgatgttctgtccatggagg	Protospacer
 ********* ***** *******  .. .

221. spacer 2.14|1174464|30|NC_012891|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP015879 (Pseudomonas citronellolis strain SJTE-3 plasmid pRBL16, complete sequence) position: , mismatch: 9, identity: 0.7

atgctcaaaaagatgtgctgtccaacagta	CRISPR spacer
ctgctcaaaatgatgttctgtccatggagg	Protospacer
 ********* ***** *******  .. .

222. spacer 2.14|1174464|30|NC_012891|CRISPRCasFinder,CRT,PILER-CR matches to NZ_KY883660 (Pseudomonas putida strain SY153 plasmid pSY153-MDR, complete sequence) position: , mismatch: 9, identity: 0.7

atgctcaaaaagatgtgctgtccaacagta	CRISPR spacer
ctgctcaaaatgatgttctgtccatggagg	Protospacer
 ********* ***** *******  .. .

223. spacer 3.2|1601618|37|NC_012891|PILER-CR matches to MN694381 (Marine virus AFVG_250M1042, complete genome) position: , mismatch: 10, identity: 0.73

gtcaactattttttctgtttttttgtatttttttctc	CRISPR spacer
tttttttattttttttgtttttttgttttttttattt	Protospacer
 *.  .********.*********** ****** .*.

224. spacer 3.2|1601618|37|NC_012891|PILER-CR matches to MK496795 (Capybara microvirus Cap3_SP_446, complete genome) position: , mismatch: 10, identity: 0.73

gtcaactattttttctgtttttttgtatttttttctc	CRISPR spacer
ttttaaatttttttatgtttttttttatttttttgtg	Protospacer
 *. *   ****** ********* ********* *

225. spacer 3.2|1601618|37|NC_012891|PILER-CR matches to NZ_CP034130 (Klebsiella quasipneumoniae strain G4584 plasmid pG4584_218.9Kb, complete sequence) position: , mismatch: 11, identity: 0.703

gtcaactattttttctgtttttttgtatttttttctc	CRISPR spacer
tttttttattttttctctttttttttattttttctct	Protospacer
 *.  .********** ******* ********....

226. spacer 3.2|1601618|37|NC_012891|PILER-CR matches to NZ_CP034138 (Klebsiella quasipneumoniae subsp. similipneumoniae strain G747 plasmid pG747_218.9Kb, complete sequence) position: , mismatch: 11, identity: 0.703

gtcaactattttttctgtttttttgtatttttttctc	CRISPR spacer
tttttttattttttctctttttttttattttttctct	Protospacer
 *.  .********** ******* ********....

227. spacer 3.2|1601618|37|NC_012891|PILER-CR matches to NZ_CP017473 (Enterobacter cloacae strain M12X01451 plasmid pM12X01451, complete sequence) position: , mismatch: 11, identity: 0.703

gtcaactattttttctgtttttttgtatttttttctc	CRISPR spacer
ttggtattttttttgtgttttttggtattttttttat	Protospacer
 * .  * ****** ******** **********. .

228. spacer 3.2|1601618|37|NC_012891|PILER-CR matches to NZ_CP010123 (Escherichia coli strain C5 plasmid A, complete genome) position: , mismatch: 11, identity: 0.703

gtcaactattttttctgtttttttgtatttttttctc	CRISPR spacer
tggagttattttttgtgtttttttgtgtttttggttt	Protospacer
   *..******** ***********.*****  .*.

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

32854 : 43267

Microbacterium_phage(16.67%)

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_012766411.1\|32854_36580_+	phosphoribosylformylglycinamidine synthase	A6N228	Microbacterium_phage	1.7e-34	25.9
WP_012766412.1\|36698_38150_+	amidophosphoribosyltransferase	A0A0M3SGR2	Mollivirus	5.5e-58	34.0
WP_041788703.1\|38302_39331_+	phosphoribosylformylglycinamidine cyclo-ligase	A0A1D7SE90	Cyanophage	6.2e-64	43.6
WP_012766414.1\|39323_39878_+	phosphoribosylglycinamide formyltransferase	M4QRX9	Synechococcus_phage	2.2e-23	34.1
WP_015057184.1\|39984_40497_+	VanZ family protein	NA	NA	NA	NA
WP_012766416.1\|40515_42060_+	bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase	Q58MG4	Prochlorococcus_phage	3.7e-76	48.4
WP_003055557.1\|42139_43267_-	SH3 domain-containing protein	F8HGP2	Streptococcus_phage	9.1e-08	28.6

DBSCAN-SWA_2

418419 : 427983

Streptococcus_phage(81.82%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_003062488.1\|418419_419184_+	ABC transporter ATP-binding protein	A0A2H4PQG7	Staphylococcus_phage	7.2e-17	28.3
WP_171841621.1\|419189_419894_+	ATP-binding cassette domain-containing protein	G9BWD6	Planktothrix_phage	3.0e-17	28.4
WP_003059946.1\|419938_420601_+	CBS domain-containing protein	M1NSC5	Streptococcus_phage	1.2e-60	57.4
WP_012766617.1\|420687_421323_+	dTMP kinase	M1PSC7	Streptococcus_phage	1.8e-69	66.3
WP_012766618.1\|421338_422211_+	DNA polymerase III subunit delta'	M1NSC1	Streptococcus_phage	7.7e-55	41.4
WP_003058683.1\|422207_423008_+	signal peptidase II	NA	NA	NA	NA
WP_003058686.1\|423000_423324_+	DNA replication initiation control protein YabA	M1PFV3	Streptococcus_phage	7.0e-30	64.2
WP_003058668.1\|423328_424192_+	16S rRNA (cytidine(1402)-2'-O)-methyltransferase	M1PLC5	Streptococcus_phage	3.5e-116	76.0
WP_003062448.1\|424218_424611_+	hypothetical protein	NA	NA	NA	NA
WP_003058655.1\|424657_425287_-	copper homeostasis protein CutC	NA	NA	NA	NA
WP_012766619.1\|425403_426495_+	3-phosphoserine/phosphohydroxythreonine transaminase	M1Q1P2	Streptococcus_phage	6.9e-130	63.1
WP_003061315.1\|426520_427072_+	GNAT family N-acetyltransferase	M1PSC3	Streptococcus_phage	3.0e-49	53.6
WP_003062357.1\|427132_427630_+	methylated-DNA--[protein]-cysteine S-methyltransferase	M1PFU9	Streptococcus_phage	1.4e-40	52.9
WP_012766620.1\|427626_427983_+	arsenate reductase family protein	M1PLC0	Streptococcus_phage	1.8e-39	65.0

DBSCAN-SWA_3

443741 : 493852

Mycobacterium_phage(14.29%)

transposase,bacteriocin,tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_041788833.1\|443741_445739_+\|tRNA	methionine--tRNA ligase	A0A1V0SHR2	Klosneuvirus	6.0e-87	35.7
WP_003055629.1\|446271_447285_+	class 1b ribonucleoside-diphosphate reductase subunit beta	R4TBI6	Mycobacterium_phage	2.9e-98	53.4
WP_003055616.1\|447288_447762_+	class Ib ribonucleoside-diphosphate reductase assembly flavoprotein NrdI	F8WQ19	Bacillus_phage	3.7e-11	37.8
WP_012766631.1\|447745_449932_+	class 1b ribonucleoside-diphosphate reductase subunit alpha	A8E2R1	Enterococcus_phage	8.3e-167	43.1
WP_003055639.1\|450229_451564_+	branched-chain amino acid transport system II carrier protein	NA	NA	NA	NA
WP_003060834.1\|451901_452765_-\|transposase	IS982 family transposase	NA	NA	NA	NA
WP_041788838.1\|452926_453280_+	hypothetical protein	NA	NA	NA	NA
WP_003054401.1\|453628_453865_+	DUF2829 domain-containing protein	NA	NA	NA	NA
WP_003054338.1\|453857_454556_+	3-oxoacyl-ACP reductase	NA	NA	NA	NA
WP_003049859.1\|454552_454795_+	DUF3977 family protein	NA	NA	NA	NA
WP_012766632.1\|454812_455262_+	ASCH domain-containing protein	NA	NA	NA	NA
WP_003054341.1\|455263_456223_+	Gfo/Idh/MocA family oxidoreductase	NA	NA	NA	NA
WP_003054334.1\|456556_457894_+	MFS transporter	NA	NA	NA	NA
WP_003061627.1\|458065_459448_+	bifunctional UDP-N-acetylglucosamine diphosphorylase/glucosamine-1-phosphate N-acetyltransferase GlmU	A0A2K9L4K9	Tupanvirus	1.6e-30	35.6
WP_003059987.1\|459478_460033_+	NUDIX hydrolase	NA	NA	NA	NA
WP_003054365.1\|460033_460285_+	hypothetical protein	NA	NA	NA	NA
WP_003054376.1\|460302_460998_+	5'-methylthioadenosine/adenosylhomocysteine nucleosidase	NA	NA	NA	NA
WP_003059888.1\|461070_461718_-	metal-dependent transcriptional regulator	NA	NA	NA	NA
WP_003054333.1\|461863_462796_+	metal ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_003054363.1\|462860_463586_+	metal ABC transporter ATP-binding protein	A0A1V0SE00	Indivirus	8.1e-18	31.8
WP_003054335.1\|463586_464435_+	metal ABC transporter permease	NA	NA	NA	NA
WP_012766633.1\|464565_465372_-	peptidylprolyl isomerase	A0A2H4UTF4	Bodo_saltans_virus	2.1e-22	37.8
WP_041789178.1\|465589_467998_+	DNA translocase FtsK	S5VNE3	Mycobacterium_phage	2.5e-87	51.1
WP_012766635.1\|468066_468420_-	DUF3397 domain-containing protein	NA	NA	NA	NA
WP_171841606.1\|468575_469598_-\|transposase	IS30 family transposase	H7BUM7	unidentified_phage	4.8e-40	32.7
WP_003049875.1\|469839_470265_+	50S ribosomal protein L11	NA	NA	NA	NA
WP_003049876.1\|470370_471060_+	50S ribosomal protein L1	NA	NA	NA	NA
WP_003054374.1\|471517_471685_-	hypothetical protein	NA	NA	NA	NA
WP_003049878.1\|471966_472695_+	UMP kinase	NA	NA	NA	NA
WP_003054381.1\|472723_473281_+	ribosome recycling factor	NA	NA	NA	NA
WP_012766638.1\|473389_474247_+	S1 RNA-binding domain-containing protein	NA	NA	NA	NA
WP_003054395.1\|474319_474829_+	peptide-methionine (S)-S-oxide reductase MsrA	NA	NA	NA	NA
WP_003054340.1\|474825_475041_+	YozE family protein	NA	NA	NA	NA
WP_012766639.1\|475199_476396_+	LysM peptidoglycan-binding domain-containing protein	A0A0E3XB61	Gordonia_phage	2.8e-15	38.7
WP_041788841.1\|476706_478479_+	oleate hydratase	NA	NA	NA	NA
WP_012766641.1\|478639_479701_+	PhoH family protein	W8D063	Erwinia_phage	1.2e-46	50.0
WP_003054351.1\|479747_480323_+	uracil-DNA glycosylase family protein	NA	NA	NA	NA
WP_003054373.1\|480481_480979_+	rRNA maturation RNase YbeY	NA	NA	NA	NA
WP_003054389.1\|480959_481367_+	diacylglycerol kinase	NA	NA	NA	NA
WP_012766643.1\|481487_482384_+	GTPase Era	NA	NA	NA	NA
WP_012766645.1\|482706_484113_-	ATP-binding cassette domain-containing protein	F2Y2R6	Organic_Lake_phycodnavirus	1.2e-14	27.6
WP_003062179.1\|484416_484644_+	hypothetical protein	NA	NA	NA	NA
WP_002994587.1\|484692_485010_+	hypothetical protein	NA	NA	NA	NA
WP_012766647.1\|485417_485657_+\|bacteriocin	bacteriocin	NA	NA	NA	NA
WP_003054392.1\|485670_485856_+	hypothetical protein	NA	NA	NA	NA
WP_012766649.1\|486539_487289_+	response regulator transcription factor	NA	NA	NA	NA
WP_012766650.1\|487289_488624_+	GHKL domain-containing protein	NA	NA	NA	NA
WP_011017462.1\|488684_488810_-\|bacteriocin	ComC/BlpC family leader-containing pheromone/bacteriocin	NA	NA	NA	NA
WP_012766651.1\|488900_490265_-\|bacteriocin	bacteriocin secretion accessory protein	NA	NA	NA	NA
WP_003062135.1\|490275_492429_-	peptide cleavage/export ABC transporter	W8CYL7	Bacillus_phage	5.7e-43	28.3
WP_171841606.1\|492829_493852_+\|transposase	IS30 family transposase	H7BUM7	unidentified_phage	4.8e-40	32.7

DBSCAN-SWA_4

1075304 : 1124047

Streptococcus_phage(68.63%)

integrase,portal,capsid,holin,transposase,terminase

attL 1081640:1081699|attR 1117122:1117233

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_003053549.1\|1075304_1078415_-	DNA polymerase III subunit alpha	A0A2L1IZ23	Streptomyces_phage	2.6e-121	29.3
WP_003053565.1\|1078601_1078973_+	GntR family transcriptional regulator	NA	NA	NA	NA
WP_012767007.1\|1078972_1079671_+	ABC transporter ATP-binding protein	A0A2H4PQG7	Staphylococcus_phage	3.7e-20	27.7
WP_003053541.1\|1079680_1080469_+	hypothetical protein	NA	NA	NA	NA
WP_003053567.1\|1080604_1081219_-	TVP38/TMEM64 family protein	M1Q152	Streptococcus_phage	8.6e-53	55.4
1081640:1081699	attL	NA	NA	NA	NA
WP_012767008.1\|1081809_1081998_-	hypothetical protein	A3F673	Streptococcus_phage	3.9e-17	76.3
WP_012767009.1\|1082236_1083220_+	DNA/RNA non-specific endonuclease	A7J2B8	Streptococcus_phage	9.2e-166	97.7
WP_011888781.1\|1083281_1083482_-	CsbD family protein	J7KJ36	Streptococcus_phage	5.3e-20	81.8
WP_012767010.1\|1083670_1084183_-	hypothetical protein	NA	NA	NA	NA
WP_012767011.1\|1084579_1085782_-	glucosaminidase domain-containing protein	A7J2B5	Streptococcus_phage	1.2e-220	91.0
WP_012767013.1\|1085893_1086349_-\|holin	phage holin family protein	A0A0M4R3G6	Streptococcus_phage	2.4e-60	78.8
WP_012767014.1\|1086351_1087008_-	hypothetical protein	Q938J7	Temperate_phage	2.1e-20	32.7
WP_012767015.1\|1087010_1087439_-	DUF1617 family protein	Q938J8	Temperate_phage	1.9e-54	79.3
WP_012767016.1\|1087448_1089158_-	hypothetical protein	M1PRW0	Streptococcus_phage	1.6e-40	61.2
WP_012767017.1\|1089166_1089820_-	hypothetical protein	A0A097PBF7	Streptococcus_pyogenes_phage	1.0e-80	71.0
WP_012767018.1\|1089819_1090605_-	collagen-like protein	A3F657	Streptococcus_phage	2.6e-17	72.6
WP_012767021.1\|1092540_1093236_-	hypothetical protein	M1Q167	Streptococcus_phage	5.4e-43	40.4
WP_012767023.1\|1095251_1095812_-	HNH endonuclease	Q38127	Lactococcus_phage	8.9e-81	79.0
WP_012767024.1\|1095898_1096489_-	hypothetical protein	Q38126	Lactococcus_phage	3.5e-51	61.4
WP_012767025.1\|1096488_1096860_-	DUF5361 domain-containing protein	M1PL84	Streptococcus_phage	1.6e-33	59.2
WP_041788999.1\|1096874_1097138_-	hypothetical protein	A0A0B5A2F3	Streptococcus_phage	3.8e-18	54.1
WP_041789002.1\|1097148_1097742_-	hypothetical protein	M1PKG8	Streptococcus_phage	2.4e-60	64.5
WP_012767027.1\|1097753_1098089_-	hypothetical protein	A0A1P8BMR5	Lactococcus_phage	8.3e-34	64.0
WP_041789004.1\|1098089_1098326_-	hypothetical protein	A0A0B5A7G2	Streptococcus_phage	1.1e-21	72.7
WP_012767029.1\|1098318_1098657_-	hypothetical protein	M1PFF8	Streptococcus_phage	5.8e-43	70.3
WP_012767030.1\|1098619_1099039_-	hypothetical protein	A0A0B5A2F6	Streptococcus_phage	1.3e-47	71.5
WP_012767031.1\|1099059_1099293_-	hypothetical protein	M1PL08	Streptococcus_phage	3.9e-14	56.8
WP_012767032.1\|1099294_1100188_-\|capsid	phage major capsid protein	M1PFL0	Streptococcus_phage	4.4e-122	71.3
WP_041789006.1\|1100205_1100646_-	DUF4355 domain-containing protein	A0A0B5A7G6	Streptococcus_phage	2.1e-37	59.0
WP_041789008.1\|1100725_1102141_-\|terminase	terminase	A0A0B5A091	Streptococcus_phage	2.9e-213	74.2
WP_012767035.1\|1102204_1102474_-	hypothetical protein	A0A097PAR8	Streptococcus_pyogenes_phage	2.8e-24	74.4
WP_003047515.1\|1102535_1102733_-	hypothetical protein	S6C469	Thermus_phage	1.1e-06	46.2
WP_012767036.1\|1102732_1103944_-	hypothetical protein	Q7Y4I9	Streptococcus_phage	2.8e-116	66.8
WP_012767037.1\|1103936_1105205_-\|portal	phage portal protein	A0A1X9I693	Streptococcus_phage	4.3e-192	76.7
WP_003051714.1\|1105201_1105558_-	hypothetical protein	M1PRL3	Streptococcus_phage	1.1e-07	60.0
WP_011054690.1\|1105705_1106050_-	HNH endonuclease	M1Q0W7	Streptococcus_phage	3.2e-41	69.4
WP_012767038.1\|1106157_1106577_-	DUF1492 domain-containing protein	A0A1X9I5B5	Streptococcus_phage	3.5e-58	82.0
WP_012767039.1\|1106652_1106904_-	hypothetical protein	M1PF60	Streptococcus_phage	1.6e-18	59.0
WP_012767040.1\|1106917_1107187_-	hypothetical protein	A0A1P8VVR6	Streptococcus_phage	5.8e-46	98.9
WP_012767042.1\|1107361_1107874_-	hypothetical protein	Q708P9	Streptococcus_phage	8.7e-67	77.4
WP_012767043.1\|1107870_1108212_-	hypothetical protein	M1PKX3	Streptococcus_phage	1.7e-13	42.0
WP_012767044.1\|1108386_1108554_-	hypothetical protein	A0A1S5SEF3	Streptococcus_phage	5.1e-08	55.6
WP_012767045.1\|1108563_1109361_-	PD-(D/E)XK nuclease-like domain-containing protein	J7KGZ1	Streptococcus_phage	4.7e-136	88.3
WP_012767046.1\|1109353_1109554_-	hypothetical protein	NA	NA	NA	NA
WP_012767047.1\|1109550_1110477_-	recombinase RecT	M1NRN6	Streptococcus_phage	1.9e-91	72.2
WP_012767048.1\|1110637_1110844_-	hypothetical protein	NA	NA	NA	NA
WP_012767049.1\|1110852_1110993_-	hypothetical protein	NA	NA	NA	NA
WP_010922205.1\|1110989_1111223_-	hypothetical protein	Q938N1	Temperate_phage	2.8e-36	96.1
WP_012767050.1\|1111203_1111590_-	DnaD domain-containing protein	Q938N2	Temperate_phage	9.6e-26	50.4
WP_012767052.1\|1112079_1112265_-	hypothetical protein	Q938N3	Temperate_phage	1.8e-22	93.4
WP_012767053.1\|1112266_1112557_-	hypothetical protein	A0A097PAT8	Streptococcus_pyogenes_phage	6.1e-41	84.2
WP_012767054.1\|1112846_1113050_-	hypothetical protein	NA	NA	NA	NA
WP_012767055.1\|1113107_1113521_+	hypothetical protein	NA	NA	NA	NA
WP_019418745.1\|1113522_1113681_-	hypothetical protein	NA	NA	NA	NA
WP_012767056.1\|1113693_1113909_-	hypothetical protein	M1Q1B4	Streptococcus_phage	6.9e-26	81.2
WP_012767057.1\|1114215_1114566_+	helix-turn-helix transcriptional regulator	M1PKY8	Streptococcus_phage	2.1e-43	75.7
WP_012767058.1\|1114568_1114955_+	ImmA/IrrE family metallo-endopeptidase	A7J268	Streptococcus_phage	2.2e-38	69.8
WP_012767059.1\|1114965_1115388_+	hypothetical protein	NA	NA	NA	NA
WP_050742413.1\|1115600_1115867_+	hypothetical protein	M1PF81	Streptococcus_phage	9.6e-09	87.1
WP_012767061.1\|1115990_1117079_+\|integrase	site-specific integrase	A0A097PAS9	Streptococcus_pyogenes_phage	1.4e-202	98.6
WP_003060624.1\|1117441_1118062_+	DUF3862 domain-containing protein	NA	NA	NA	NA
1117122:1117233	attR	NA	NA	NA	NA
WP_003057625.1\|1119924_1121130_-	30S ribosomal protein S1	NA	NA	NA	NA
WP_003057631.1\|1121518_1121749_-	DUF2969 domain-containing protein	NA	NA	NA	NA
WP_015057616.1\|1121812_1122835_-	branched-chain amino acid aminotransferase	NA	NA	NA	NA
WP_012767065.1\|1123036_1124047_+\|transposase	IS30 family transposase	H7BWC8	unidentified_phage	3.0e-34	33.3

DBSCAN-SWA_5

1565919 : 1604434

Streptococcus_pyogenes_phage(51.92%)

integrase,portal,tail,capsid,holin,terminase

attL 1558329:1558344|attR 1606235:1606250

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
1558329:1558344	attL	NA	NA	NA	NA
WP_012767354.1\|1565919_1566849_-	ATP-binding cassette domain-containing protein	A0A2H4PQG7	Staphylococcus_phage	2.6e-37	43.3
WP_012767355.1\|1567308_1568667_-	23S rRNA (uracil(1939)-C(5))-methyltransferase RlmD	NA	NA	NA	NA
WP_012767356.1\|1568856_1569039_-	hypothetical protein	A3F673	Streptococcus_phage	2.6e-18	75.0
WP_012767357.1\|1569209_1569584_+	anti-CRISPR protein AcrIIA3	NA	NA	NA	NA
WP_012767358.1\|1569583_1570186_+	AP2 domain-containing protein	A0A096XV31	Lactococcus_phage	3.4e-09	31.5
WP_023611751.1\|1570187_1570403_+	hypothetical protein	B3GW25	Streptococcus_phage	3.7e-11	52.1
WP_003055855.1\|1570471_1570711_+	hypothetical protein	NA	NA	NA	NA
WP_012767360.1\|1570913_1572263_-	glucosaminidase domain-containing protein	A0A1P8VVM5	Streptococcus_phage	2.1e-197	81.9
WP_012767361.1\|1572264_1572597_-\|holin	phage holin	A0A097PBF6	Streptococcus_pyogenes_phage	2.2e-47	90.9
WP_012767362.1\|1572596_1572920_-	hypothetical protein	A0A097PAX2	Streptococcus_pyogenes_phage	4.7e-50	95.3
WP_012767363.1\|1572932_1573097_-	hypothetical protein	A0A097PAU6	Streptococcus_pyogenes_phage	2.3e-21	92.6
WP_012767364.1\|1573068_1573419_-	DUF1366 domain-containing protein	A0A097PAX5	Streptococcus_pyogenes_phage	2.1e-43	76.7
WP_012767365.1\|1573434_1575312_-	hypothetical protein	A0A097PAT0	Streptococcus_pyogenes_phage	1.8e-122	43.4
WP_012767366.1\|1575322_1578691_-\|tail	phage tail protein	A0A097PBF5	Streptococcus_pyogenes_phage	0.0e+00	78.1
WP_012767367.1\|1578691_1580176_-\|tail	phage tail family protein	A0A097PAW9	Streptococcus_pyogenes_phage	2.6e-180	64.5
WP_012767368.1\|1580176_1581361_-	hypothetical protein	A0A097PAU2	Streptococcus_pyogenes_phage	3.3e-170	94.9
WP_012767369.1\|1581579_1582140_-	HNH endonuclease	Q38127	Lactococcus_phage	3.0e-97	94.1
WP_012767370.1\|1582205_1582910_-	hypothetical protein	A0A097PAU2	Streptococcus_pyogenes_phage	2.8e-71	89.2
WP_012767371.1\|1582902_1583361_-	hypothetical protein	A0A097PAX1	Streptococcus_pyogenes_phage	1.5e-78	95.4
WP_012767372.1\|1583333_1583651_-	hypothetical protein	A0A097PAS6	Streptococcus_pyogenes_phage	4.1e-51	97.1
WP_012767373.1\|1583662_1584169_-\|tail	phage major tail protein, TP901-1 family	A0A097PBF4	Streptococcus_pyogenes_phage	2.9e-78	98.7
WP_012767374.1\|1584180_1584591_-	DUF5072 family protein	A0A097PAW5	Streptococcus_pyogenes_phage	2.3e-70	99.3
WP_012767375.1\|1584592_1584988_-	hypothetical protein	A0A097PAT9	Streptococcus_pyogenes_phage	8.2e-57	94.7
WP_012767376.1\|1584984_1585296_-	hypothetical protein	A0A097PAW7	Streptococcus_pyogenes_phage	9.4e-48	94.2
WP_012767377.1\|1585292_1585637_-	hypothetical protein	A0A097PAS2	Streptococcus_pyogenes_phage	2.4e-52	94.7
WP_012767378.1\|1585650_1585944_-	Rho termination factor N-terminal domain-containing protein	A0A097PBF3	Streptococcus_pyogenes_phage	4.1e-45	96.9
WP_012767379.1\|1585955_1586846_-	hypothetical protein	A0A097PAW2	Streptococcus_pyogenes_phage	5.2e-83	97.5
WP_041789106.1\|1586863_1587433_-	DUF4355 domain-containing protein	A0A097PAW3	Streptococcus_pyogenes_phage	1.0e-55	85.3
WP_012767381.1\|1587675_1587903_-	hypothetical protein	Q938K9	Temperate_phage	3.6e-17	61.4
WP_012767382.1\|1587909_1588818_-\|capsid	minor capsid protein	A0A097PBF2	Streptococcus_pyogenes_phage	9.0e-83	93.9
WP_012767383.1\|1588786_1590112_-\|portal	phage portal protein	A0A097PAT2	Streptococcus_pyogenes_phage	3.9e-236	96.5
WP_012767384.1\|1590111_1591386_-\|terminase	PBSX family phage terminase large subunit	A0A097PAV9	Streptococcus_pyogenes_phage	9.9e-237	93.4
WP_012767385.1\|1591375_1591756_-	hypothetical protein	A0A097PAR5	Streptococcus_pyogenes_phage	3.0e-64	99.2
WP_012767387.1\|1592284_1592725_-	ArpU family transcriptional regulator	Q938L8	Temperate_phage	2.5e-78	98.6
WP_012767389.1\|1593082_1593616_-	DUF1642 domain-containing protein	A0A2I6QQU0	Streptococcus_phage	8.0e-23	48.0
WP_012767390.1\|1593605_1593854_-	hypothetical protein	NA	NA	NA	NA
WP_012767391.1\|1593857_1594127_-	hypothetical protein	J7KK64	Streptococcus_phage	4.8e-16	60.5
WP_012767392.1\|1594123_1594528_-	hypothetical protein	A0A1S5SAN0	Streptococcus_phage	1.8e-11	37.3
WP_012767393.1\|1594524_1594737_-	hypothetical protein	NA	NA	NA	NA
WP_012767395.1\|1595114_1595402_-	DUF1599 domain-containing protein	J7KBY0	Streptococcus_phage	4.8e-30	66.3
WP_012767396.1\|1595398_1595647_-	hypothetical protein	Q938M4	Temperate_phage	3.7e-31	82.7
WP_012767397.1\|1595643_1596000_-	hypothetical protein	A0A1P8VVP9	Streptococcus_phage	2.4e-39	68.6
WP_012767398.1\|1595996_1596437_-	RusA family crossover junction endodeoxyribonuclease	A0A097PAS0	Streptococcus_pyogenes_phage	2.7e-72	89.7
WP_012767400.1\|1596645_1597065_-	single-stranded DNA-binding protein	Q938M7	Temperate_phage	5.5e-67	92.8
WP_012767401.1\|1597057_1597732_-	ERF family protein	Q938M8	Temperate_phage	8.2e-97	83.5
WP_012767402.1\|1597732_1598215_-	siphovirus Gp157 family protein	Q938M9	Temperate_phage	2.7e-46	94.4
WP_012767403.1\|1598235_1598490_-	hypothetical protein	Q938N0	Temperate_phage	1.7e-39	90.5
WP_012767404.1\|1598476_1598827_-	hypothetical protein	A0A097PAU3	Streptococcus_pyogenes_phage	3.8e-37	68.1
WP_012767406.1\|1598964_1599747_-	ATP-binding protein	A0A097PAQ0	Streptococcus_pyogenes_phage	2.7e-144	97.7
WP_012767407.1\|1599733_1600549_-	phage replisome organizer N-terminal domain-containing protein	A0A1L2JXW0	Streptococcus_phage	7.9e-70	60.5
WP_012767408.1\|1600549_1600756_-	hypothetical protein	NA	NA	NA	NA
WP_012767409.1\|1600736_1600877_-	hypothetical protein	A0A097PAR2	Streptococcus_pyogenes_phage	8.0e-15	92.9
WP_012767410.1\|1600907_1601159_-	hypothetical protein	A0A1P8VVV6	Streptococcus_phage	7.6e-40	94.0
WP_012767411.1\|1601288_1601501_-	helix-turn-helix transcriptional regulator	J7KBP9	Streptococcus_phage	9.2e-31	95.7
WP_012767412.1\|1601697_1602039_+	helix-turn-helix transcriptional regulator	J7KJZ4	Streptococcus_phage	3.4e-51	91.2
WP_012767413.1\|1602022_1602400_+	ImmA/IrrE family metallo-endopeptidase	A0A1P8VVK5	Streptococcus_phage	6.4e-67	96.8
WP_012767414.1\|1602408_1603095_+	hypothetical protein	A0A1P8VVT3	Streptococcus_phage	1.0e-118	96.9
WP_041789110.1\|1603267_1604434_+\|integrase	tyrosine-type recombinase/integrase	A3F610	Streptococcus_phage	1.3e-78	42.8
1606235:1606250	attR	NA	NA	NA	NA

DBSCAN-SWA_6

2030557 : 2042058

Streptococcus_phage(50.0%)

tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_012767643.1\|2030557_2033113_-	DNA mismatch repair protein MutS	A0A1V0SGG8	Hokovirus	5.9e-39	25.2
WP_012767644.1\|2033099_2033453_-	YlbF family regulator	NA	NA	NA	NA
WP_003055516.1\|2033449_2033887_-	arginine repressor	NA	NA	NA	NA
WP_012767645.1\|2034175_2035867_+\|tRNA	arginine--tRNA ligase	A0A2I2L3K1	Orpheovirus	4.9e-74	32.4
WP_003062372.1\|2035936_2037334_-	ABC-F family ATP-binding cassette domain-containing protein	A0A1B0RXA0	Streptococcus_phage	8.5e-48	28.3
WP_003055540.1\|2037511_2038426_-	YitT family protein	M1Q1P6	Streptococcus_phage	2.0e-53	40.1
WP_003060132.1\|2038455_2039355_-	YitT family protein	M1Q1P6	Streptococcus_phage	6.1e-47	35.2
WP_003055524.1\|2039375_2040317_-	YitT family protein	NA	NA	NA	NA
WP_012767646.1\|2040309_2042058_-\|tRNA	aspartate--tRNA ligase	A0A1V0SJ84	Klosneuvirus	4.5e-14	26.1

DBSCAN-SWA_7

2062500 : 2073395

Streptococcus_phage(66.67%)

integrase

attL 2059630:2059643|attR 2072212:2072225

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
2059630:2059643	attL	NA	NA	NA	NA
WP_003045773.1\|2062500_2062674_-	hypothetical protein	A0A1X9I5U0	Streptococcus_phage	6.6e-11	59.6
WP_012767666.1\|2062960_2064574_-	hypothetical protein	A0A1P8BMF9	Lactococcus_phage	9.2e-147	52.9
WP_012767667.1\|2064563_2065085_-	hypothetical protein	NA	NA	NA	NA
WP_012767668.1\|2065094_2065463_-	hypothetical protein	A0A1X9I6M4	Streptococcus_phage	3.4e-12	47.1
WP_014612651.1\|2065371_2065569_-	hypothetical protein	NA	NA	NA	NA
WP_014612652.1\|2065549_2065690_-	hypothetical protein	NA	NA	NA	NA
WP_012767669.1\|2065686_2066019_-	hypothetical protein	NA	NA	NA	NA
WP_014612653.1\|2066242_2066485_-	hypothetical protein	NA	NA	NA	NA
WP_012767671.1\|2066547_2067111_-	hypothetical protein	A0A0A7S0G2	Clostridium_phage	7.4e-27	47.1
WP_011285321.1\|2067126_2067315_-	helix-turn-helix transcriptional regulator	A0A1X9I5U7	Streptococcus_phage	1.7e-12	59.7
WP_012767672.1\|2067483_2067927_+	helix-turn-helix transcriptional regulator	A0A1X9I723	Streptococcus_phage	1.8e-07	48.6
WP_012767673.1\|2068237_2068762_+	hypothetical protein	A8ASM1	Listeria_phage	5.3e-11	34.3
WP_012767674.1\|2069005_2070169_+\|integrase	site-specific integrase	A0A1X9I6A9	Streptococcus_phage	2.1e-161	70.5
WP_002982092.1\|2070325_2070937_-	30S ribosomal protein S4	NA	NA	NA	NA
WP_003055134.1\|2071125_2071593_-	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_003055136.1\|2071745_2072018_-	Veg family protein	NA	NA	NA	NA
WP_041789162.1\|2072033_2073395_-	replicative DNA helicase	A0A1P8VVQ6	Streptococcus_phage	1.1e-153	63.0
2072212:2072225	attR	NA	NA	NA	NA

Anti-CRISPR protein detection

Acr_ID: NC_012891.1|WP_000384270.1|257180_257507_+|replication-initiator-protein-A

Click the colored protein region to show detailed information

Acr_ID: NC_012891.1|WP_012767393.1|1594524_1594737_-|hypothetical-protein

Click the colored protein region to show detailed information

Acr ID

Acr position

Acr size

Homology with known anti

Neighbor HTH/AcRanker

Neighbor Aca

In prophage

Protospacer in prophage

NC_012891.1|WP_000384270.1|257180_257507_+|replication-initiator-protein-A

257180_257507_+

108 aa aa

hit_Aca_id	identity	query_coverage	hit_coverage
gnl\|BL_ORD_ID\|63	0.9444444444444444	1	1.0

NC_012891.1|WP_012767393.1|1594524_1594737_-|hypothetical-protein

1594524_1594737_-

70 aa aa

1565919-1604434

yes

CRISPR ID	CRISPR type	Spacer info	Spacer location	Spacer length	Protospacer location	Mismatch
NC_012891_2	TypeII	2.7\|1174000\|32\|NC_012891\|CRISPRCasFinder,CRT,PILER-CR	1174000-1174031	32	1596390-1596359	0

1. spacer 2.7|1174000|32|NC_012891|CRISPRCasFinder,CRT,PILER-CR matches to NC_012891 position: 1596390-1596359, mismatch: 0

acgctttagcagatggagcggggcttacgagg	CRISPR spacer
acgctttagcagatggagcggggcttacgagg	Protospacer
********************************

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. NC_012891

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

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Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information