CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NC_013939	Deferribacter desulfuricans SSM1, complete genome	3 crisprs	DEDDh,csa3,WYL,cas3,cas5,cas7,cas8b1,cas6,cas2,cas1,cas4,Cas9_archaeal	0	5	2	0
NC_013940	Deferribacter desulfuricans SSM1 megaplasmid pDF308, complete sequence	2 crisprs	c2c9_V-U4,cas3,cas5,cas7,cas8b1,cas6	0	19	4	0

Results visualization

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CRISPR-Cas detection and classification

Crispr_ID: NC_013939_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_013939_1

311406-311545

Orphan

Consensus_repeat	Method
ATGGTCCAGGATTTGGTAGAGGATATGGTATGATGGGGCCTGGA	CRISPRCasFinder

1 spacers

The CRISPR arrays of NC_013939_1

>merge|NC_013939|1|311406-311545|CRISPRCasFinder
ATGGTCCAGGATTTGGTAGAGGATATGGTATGATGGGGCCTGGAATGATGGGTTCTGGAATGATGGGGCCTGGATACGGTTATCAGGGTAATGGTTATGGTCCAGGATTTGGTAGAGGATATGGTATGATGGGGCCTGGA

>NC_013939|1|1|311406-311545|CRISPRCasFinder
ATGGTCCAGGATTTGGTAGAGGATATGGTATGATGGGGCCTGGA	ATGATGGGTTCTGGAATGATGGGGCCTGGATACGGTTATCAGGGTAATGGTT
ATGGTCCAGGATTTGGTAGAGGATATGGTATGATGGGGCCTGGA

Protein	Signature genes	Signature genes Name	Protein_function
NC_013939.1\|WP_013007051.1\|302553_302931_+\|hypothetical-protein	unknown	unknown	unknown
NC_013939.1\|WP_013007058.1\|310339_310756_+\|SoxR-reducing-system-RseC-family-protein	unknown	unknown	gnl\|CDD\|377263
NC_013939.1\|WP_013007065.1\|315047_315236_-\|50S-ribosomal-protein-L28	unknown	unknown	gnl\|CDD\|234736
NC_013939.1\|WP_013007055.1\|308172_308445_+\|metal-sensing-transcriptional-repressor	unknown	unknown	gnl\|CDD\|197394
NC_013939.1\|WP_041223545.1\|305424_307881_+\|copper-translocating-P-type-ATPase	unknown	unknown	gnl\|CDD\|319783
NC_013939.1\|WP_013007056.1\|308649_308886_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|225993
NC_013939.1\|WP_013007063.1\|314119_314371_+\|hypothetical-protein	unknown	unknown	unknown
NC_013939.1\|WP_153801501.1\|314373_315015_+\|dephospho-CoA-kinase	unknown	unknown	gnl\|CDD\|234620
NC_013939.1\|WP_013007050.1\|302089_302488_+\|hypothetical-protein	unknown	unknown	unknown
NC_013939.1\|WP_193333235.1\|311889_312132_+\|SHOCT-domain-containing-protein	unknown	unknown	gnl\|CDD\|225993
NC_013939.1\|WP_013007062.1\|313374_314139_+\|fumarylacetoacetate-hydrolase-family-protein	unknown	unknown	gnl\|CDD\|223257
NC_013939.1\|WP_013007054.1\|307899_308130_+\|heavy-metal-associated-domain-containing-protein	unknown	unknown	gnl\|CDD\|182635
NC_013939.1\|WP_013007067.1\|317801_318812_+\|uroporphyrinogen-decarboxylase	unknown	unknown	gnl\|CDD\|234644
NC_013939.1\|WP_013007052.1\|302956_305287_+\|cadmium-translocating-P-type-ATPase	unknown	unknown	gnl\|CDD\|319847
NC_013939.1\|WP_013007070.1\|320612_321200_+\|UbiX-family-flavin-prenyltransferase	unknown	unknown	gnl\|CDD\|180312
NC_013939.1\|WP_013007068.1\|318811_319762_+\|ferrochelatase	unknown	unknown	gnl\|CDD\|234585
NC_013939.1\|WP_013007069.1\|319764_320616_+\|UbiA-family-prenyltransferase	unknown	unknown	gnl\|CDD\|237247
NC_013939.1\|WP_084742569.1\|308924_310316_+\|multicopper-oxidase-domain-containing-protein	unknown	unknown	gnl\|CDD\|236810
NC_013939.1\|WP_013007059.1\|310771_311158_+\|DUF302-domain-containing-protein	unknown	unknown	gnl\|CDD\|269820
NC_013939.1\|WP_041223547.1\|315392_317414_-\|PAS-domain-S-box-protein	unknown	unknown	gnl\|CDD\|236901

Protein	Function_ID	Function_description	E-value
NC_013939.1\|WP_013007058.1\|310339_310756_+\|SoxR-reducing-system-RseC-family-protein	gnl\|CDD\|377263	pfam04246, RseC_MucC, Positive regulator of sigma(E), RseC/MucC. This bacterial family of integral membrane proteins represents a positive regulator of the sigma(E) transcription factor, namely RseC/MucC. The sigma(E) transcription factor is up-regulated by cell envelope protein misfolding, and regulates the expression of genes that are collectively termed ECF (devoted to Extra-Cellular Functions). In Pseudomonas aeruginosa, de-repression of sigma(E) is associated with the alginate-overproducing phenotype characteristic of chronic respiratory tract colonisation in cystic fibrosis patients. The mechanism by which RseC/MucC positively regulates the sigma(E) transcription factor is unknown. RseC is also thought to have a role in thiamine biosynthesis in Salmonella typhimurium. In addition, this family also includes an N-terminal part of RnfF, a Rhodobacter capsulatus protein, of unknown function, that is essential for nitrogen fixation. This protein also contains an ApbE domain pfam02424, which is itself involved in thiamine biosynthesis.	1.12437e-22
NC_013939.1\|WP_013007055.1\|308172_308445_+\|metal-sensing-transcriptional-repressor	gnl\|CDD\|197394	cd10159, CsoR-like_DUF156_2, Uncharacterized family 2; belongs to a superfamily containing transcriptional regulators CsoR (copper-sensitive operon repressor), RcnR, and FrmR, and related domains; this family was previously known as part of DUF156. Uncharacterized family 2, belonging to a larger superfamily that contains various transcriptional regulators that respond to different stressors such as Cu(I), Ni(I), sulfite, and formaldehyde, and includes CsoRs (copper-sensitive operon repressors). CsoRs form homotetramers (dimer of dimers). In Mycobacterium tuberculosis CsoR, within each dimer, two Cys residues on opposite subunits, along with a His residue, bind the Cu(I) ion (forming a triagonal S2N coordination complex, C-H-C). These residues are conserved in the majority of members of this superfamily, including this family, and a conserved Tyr and a Glu residue that facilitate allosteric regulation of DNA binding for CsoRs are also conserved.	1.79094e-31
NC_013939.1\|WP_041223545.1\|305424_307881_+\|copper-translocating-P-type-ATPase	gnl\|CDD\|319783	cd02094, P-type_ATPase_Cu-like, P-type heavy metal-transporting ATPase, similar to human copper-transporting ATPases, ATP7A and ATP7B. The mammalian copper-transporting P-type ATPases, ATP7A and ATP7B are key molecules required for the regulation and maintenance of copper homeostasis. Menkes and Wilson diseases are caused by mutation in ATP7A and ATP7B respectively. This subfamily includes other copper-transporting ATPases such as: Bacillus subtilis CopA , Archeaoglobus fulgidus CopA, and Saccharomyces cerevisiae Ccc2p. This subclass of P-type ATPase is also referred to as CPx-type ATPases because their amino acid sequences contain a characteristic CPC or CPH motif associated with a stretch of hydrophobic amino acids and N-terminal ion-binding sequences. This subfamily belongs to the P-type ATPases, a large family of integral membrane transporters that are of critical importance in all kingdoms of life. They generate and maintain (electro-) chemical gradients across cellular membranes, by translocating cations, heavy metals and lipids, and are distinguished from other main classes of transport ATPases (F- , V- , and ABC- type) by the formation of a phosphorylated (P-) intermediate state in the catalytic cycle.	0
NC_013939.1\|WP_013007056.1\|308649_308886_+\|hypothetical-protein	gnl\|CDD\|225993	COG3462, COG3462, Predicted membrane protein [Function unknown].	1.67416e-09
NC_013939.1\|WP_013007065.1\|315047_315236_-\|50S-ribosomal-protein-L28	gnl\|CDD\|234736	PRK00359, rpmB, 50S ribosomal protein L28; Reviewed.	2.60045e-22
NC_013939.1\|WP_153801501.1\|314373_315015_+\|dephospho-CoA-kinase	gnl\|CDD\|234620	PRK00081, coaE, dephospho-CoA kinase; Reviewed.	4.91874e-74
NC_013939.1\|WP_013007067.1\|317801_318812_+\|uroporphyrinogen-decarboxylase	gnl\|CDD\|234644	PRK00115, hemE, uroporphyrinogen decarboxylase; Validated.	1.9283e-178
NC_013939.1\|WP_193333235.1\|311889_312132_+\|SHOCT-domain-containing-protein	gnl\|CDD\|225993	COG3462, COG3462, Predicted membrane protein [Function unknown].	3.76357e-14
NC_013939.1\|WP_013007062.1\|313374_314139_+\|fumarylacetoacetate-hydrolase-family-protein	gnl\|CDD\|223257	COG0179, MhpD, 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway) [Secondary metabolites biosynthesis, transport, and catabolism].	3.31534e-112
NC_013939.1\|WP_013007054.1\|307899_308130_+\|heavy-metal-associated-domain-containing-protein	gnl\|CDD\|182635	PRK10671, copA, copper-exporting P-type ATPase CopA.	6.80037e-11
NC_013939.1\|WP_013007052.1\|302956_305287_+\|cadmium-translocating-P-type-ATPase	gnl\|CDD\|319847	cd07548, P-type_ATPase-Cd_Zn_Co_like, P-type heavy metal-transporting ATPase, similar to Bacillus subtilis CadA which appears to transport cadmium, zinc and cobalt but not copper out of the cell. Bacillus subtilis CadA/YvgW appears to transport cadmium, zinc and cobalt but not copper, out of the cell. Functions in metal ion resistance and cellular metal ion homeostasis. CadA/YvgW is also important for sporulation in B. subtilis, the significant specific expression of the cadA/yvgW gene during the late stage of sporulation, is controlled by forespore-specific sigma factor, sigma G, and mother cell-specific sigma factor, sigma E. This subfamily also includes Helicobacter pylori CadA an essential resistance pump with ion specificity towards Cd(2+), Zn(2+) and Co(2+), and Zn-transporting ATPase, ZiaA(N) in Synechocystis PCC 6803. Transcription of ziaA is induced by Zn under the control of the Zn responsive repressor ZiaR. This subclass of P-type ATPase is also referred to as CPx-type ATPases because their amino acid sequences contain a characteristic CPC or CPH motif associated with a stretch of hydrophobic amino acids and N-terminal ion-binding sequences. This subfamily belongs to the P-type ATPases, a large family of integral membrane transporters that are of critical importance in all kingdoms of life. They generate and maintain (electro-) chemical gradients across cellular membranes, by translocating cations, heavy metals and lipids, and are distinguished from other main classes of transport ATPases (F- , V- , and ABC- type) by the formation of a phosphorylated (P-) intermediate state in the catalytic cycle.	0
NC_013939.1\|WP_013007070.1\|320612_321200_+\|UbiX-family-flavin-prenyltransferase	gnl\|CDD\|180312	PRK05920, PRK05920, aromatic acid decarboxylase; Validated.	5.55316e-77
NC_013939.1\|WP_013007068.1\|318811_319762_+\|ferrochelatase	gnl\|CDD\|234585	PRK00035, hemH, ferrochelatase; Reviewed.	5.21604e-93
NC_013939.1\|WP_013007069.1\|319764_320616_+\|UbiA-family-prenyltransferase	gnl\|CDD\|237247	PRK12886, ubiA, prenyltransferase; Reviewed.	3.09802e-115
NC_013939.1\|WP_084742569.1\|308924_310316_+\|multicopper-oxidase-domain-containing-protein	gnl\|CDD\|236810	PRK10965, PRK10965, multicopper oxidase; Provisional.	5.78546e-123
NC_013939.1\|WP_013007059.1\|310771_311158_+\|DUF302-domain-containing-protein	gnl\|CDD\|269820	cd14797, DUF302, Uncharacterized domain family DUF302. These domains are mostly found in bacterial single-domain proteins and have been shown to form homodimers; they may also bind zinc. Also characterized as COG3439.	3.62739e-38
NC_013939.1\|WP_041223547.1\|315392_317414_-\|PAS-domain-S-box-protein	gnl\|CDD\|236901	PRK11360, PRK11360, two-component system sensor histidine kinase AtoS.	6.03803e-39

>NC_013939.1|WP_013007059.1|310771_311158_+|DUF302-domain-containing-protein
MNYYLSKKVSYSFDETVLKTKELLKVVGFGVLYELDMKSLLKEKIDVDIEKYFILGACNPHFGYKALQTEPNIGTVIPCNVVIRKISDNETEVSTINPVKQMSIVENTDLEEIANEIFSRLSNVISRL
>NC_013939.1|WP_013007058.1|310339_310756_+|SoxR-reducing-system-RseC-family-protein
MSKIKKVCGKVIEVNGNKVVVSVVQFAGCSHCESRDTCAVASGKSFQVELVTDKAVKVGDVVELYMMKREIYKNGFLAYILPVVALMFGAIIGSYIDKNFGNGYIAPLLSLLFLAIYFVGLRYYIRNKEVNYKINKII
>NC_013939.1|WP_084742569.1|308924_310316_+|multicopper-oxidase-domain-containing-protein
MGLAGALLVGGLGIPKGFANEKSEWDTLPTPPLLENESNEKGYVKYTLNVQQGMYEYFTGVKVPSLGYNGNILGPTLKAKKGDIVEIKVKNFLKEETTVHWHGMVVPGEMDGGPHQVVSPNGSEWTARFKVEQQAATLWYHPHGIGTTASQVYGGLGGLFIVEDENRLNLPNEYGVDDIPLVIQDKRFSQKGDLLYLTNMNDIMYGMLGNKVLVNGVIEPKKTIPRGKVRFRILNASNARSYNLKFNNKLPFVIIASDGGLLEKPIKVNDVLLSPGERVEIVADFSEFDEGSEILFGDRGYNFLTLKVGKKGKRYEIPTRLIDIDKISEKDVVRVREFVLSGLGHMVTINGKQFQMNRIDENTKIGTTEIWRVSVRMGMHGMMGGGRNSIIHNFHAHGVLFQVLKRNGRKPTGHEQGWKDTIALRNGDTVDLIMNFRKKGVFMYHCHILEHEDNGMMGQFLVS
>NC_013939.1|WP_013007056.1|308649_308886_+|hypothetical-protein
MYGYRWFGFMWMFKILVWILIIVGFVLFLIIIVRSFGGIKQHDKAVESKRLLEILKERYAKGEIDRDVYLKMKKDLES
>NC_013939.1|WP_013007055.1|308172_308445_+|metal-sensing-transcriptional-repressor
MDRKEALQYLKTARGQTDAVIKMVEGGKYCIDISKQILACIALLKKANVNILNSHLQSCVKKAISSRDGEDIERKLKELAEIIEYLNKVL
>NC_013939.1|WP_013007054.1|307899_308130_+|heavy-metal-associated-domain-containing-protein
MKKTIIIEGMSCDHCVMSVKKELESLSCTDNVEVEIGKAVVECSDIDDNALIEAVEEAGYTVKEIIAENDEKGCCN
>NC_013939.1|WP_041223545.1|305424_307881_+|copper-translocating-P-type-ATPase
MREKIFTVKGMTCASCVNRIEKKVSKIDGIEKVSVNLATEKMLVSFNPEKVDDEKIKNAVKDAGYDIEEGSDLKTVSIPIKGMTCSSCANAISKNIGKLDGIKSANVNFASEKAVVTYDPSKVRLSEIKKAITDAGYKPLDIEKGDSVDYEKKRRDKEIKTLKLKVIISAIFSIPLLYISMGHLIGLNLPDFINPQKHPFNFALAQALLVIPIIIAGYKFYTIGFKNLFKLSPNMDSLIAIGTSSAIVYGLYGVIAIFFGNTKYVNDLYFETAGVIITLILLGKYLESVSKGKTSEAIKKLMGLQPKTALILKDGKEMEIPVDEVEVGDIVIVKPGEKIPVDGVIIDGYTSVDESMLTGESIPVEKRVGDKVIGGSINKNGNIKFKATKVGKDTALAQIIKLVEEAQGSKAPIAKLADIISGYFVPVVIAIAILSAVAWYFAGAGGIFALTIFISVLVIACPCALGLATPTAIMVGTGKGAENGILIKSGEALETAHKIDTVVFDKTGTITEGKPKVTDVVVFDNFTKNDLLSLAASAEKGSEHPLGDAIVRAAEERGLEFKKVDKFLAIPGFGIEVHIDNKQIYLGNIELMREKGVDITSQMNLFEKLAKEGKTPMFVAVDGKLKGIIAVADTVKPSSVKAVEKLHEMGIKVAMITGDNKRTAEAIAKEVGIDIVLAEVLPQDKANEVKKLQERGHVVAMVGDGINDAPALAQADIGIAIGSGTDVAMESADIVLMKSDLLDVVTAIQLSKATIRNIKQNLFWAFAYNTLGIPIAAGVLHIFGGPLLSPMIAAAAMAFSSVSVVTNALRLKKFKIEH
>NC_013939.1|WP_013007052.1|302956_305287_+|cadmium-translocating-P-type-ATPase
MVKNNKKDEMLCTLDGLDCPSCAAKIEQAFHKNGLDYAMINFTSKSVKLKNSDIEKAKEILKKVEPNIHLIPNKKIQKYYLVGLSCADCAKRIEERIRKIKGLENVTLNFAAGTIAFDPRFLDKVEEIIKEVEPGVTLQKIDSDVDDEPIEENNKLATLVMVVSFFLLIIGIIFKQKLHNTPYSVAEYILFLSIYLLVGWKVLTTAIRNILRGNFFDENFLMTIATTGAIIIHQLPEAVGVMLFYYVGEYFQELAVNNSRKSIKALLDIKAEYANLRLNGTTKKVSPEMVNVGDIIVIKPGERVPLDGVVIDGVSFVDTSALTGESVPKKVKKGDDVLAGMVNTNGLLTVKVTKKFEDSSLAKILDLVENAGSRKAPTEKFITKFSRYYTPVVVIGAALLAIVPPLIIPGAAFNDWIYRALILLVISCPCALVVSIPLGYFGGIGGSSKKGILVKGANFLEVLAKLHTVVFDKTGTLTKGVFKVAEIKSINGFSEEDVLKYAAIAEANSNHPIAVSILEAYKGDLNLDDIEKYEEIAGHGIKVIYKGKEIIVGNDRFFHKENIEHQDYCNLEGTVVYVAVDGIFVGYLIISDEIKDDAKDTITKLKKIGVKRTVMLTGDDKSVAENVAAKLGIDDVYANLLPEDKVYKVEELLKGLNEKEKLAFVGDGINDAPVITRADVGIAMGGLGSDAAIEAADVVIMDDKPSKIVTAIEISRFTKKIVVQNIMFALGVKFIFVFLGSFGMATMWEAVFADVGVALLAVLNATRTLKFKGSSN
>NC_013939.1|WP_013007051.1|302553_302931_+|hypothetical-protein
MKIPLLGFFVIINLYVFSILGYAFGNTQYSNFDDKSNAHSIIKIGFWNNDCMNYYMPNKSKKKMLNIIKKYIKSNYPNWEIISIESTKVPMGIMYVIYTMDNSGNKYIFRINPWGYVMGPFEVKK
>NC_013939.1|WP_013007050.1|302089_302488_+|hypothetical-protein
MKKVFLTLLGVVGLIFILSYGYAWMGPWGGYGYNGYAQGYSSMMQGPWMDYCMDMHYGQAGAGVQISKEVAVKNVKDLLASNYPGWKVENVESFRMPMGTMYNVVASDKSGNKFMFRVNPWGYVMGPFQLIN
>NC_013939.1|WP_193333235.1|311889_312132_+|SHOCT-domain-containing-protein
MHGYGGFGGFGFMGIFSMVIWLVILIVIIYFLFMFIRDFGSKNSITKTGKNHALNILKERYARGEITKEEYLSMKNDLEN
>NC_013939.1|WP_013007062.1|313374_314139_+|fumarylacetoacetate-hydrolase-family-protein
MKLLRFKTGEVEKKGVLVDGKIRRVLGTFFDNFTVTDEIYEIDEVHFLPPVIPSKIVCIGRNYADHAKELGNEVPTEPLIFLKPNSAINNHEGLIIYPEQSNRVDYEAELAIVIKKRCKSVSEEDALDYVLGYTCFNDITARDIQKKEGKFTRAKSFDTFAPFGPFIETEFESFDNLSVKSFVNGEIRQDGNTKDMIFKVPQLISFISKVMTLYPGDVIATGTPEGVGELKPGDVVEVEVEGVGRLRNYVTKEN
>NC_013939.1|WP_013007063.1|314119_314371_+|hypothetical-protein
MSQKKIKIECLQCGVCCYFFDISTLNKPQFERCKHLRDDGKCANYENRPKVCRDFQPDEICVLISTLSFEDKIKVLKKIYGVK
>NC_013939.1|WP_153801501.1|314373_315015_+|dephospho-CoA-kinase
MYLGLTGNIASGKSTAAKFFEEYGCYTIDADEISRKVMKKGKDAYFKIVEAFGDNILLEDGEINRGKLKQIVFDDDRKRVILEDIVHPAIHEYEKRLVSEIKSKDDKAIIITQAALIVEKKTFDRFDGIIVVYVDYDSQLKRLLQRDNIDLNLAQKIISAQMPYEEKLKYANFIIDNSKDLSHLKNEVKRVYEVLKIYQYAKKQLKKRRVTFR
>NC_013939.1|WP_013007065.1|315047_315236_-|50S-ribosomal-protein-L28
MARRCDICGKGPMFGHTISHAHNVSRRVFYPNVHKVRVIENGKVVRKKVCTKCLKAGKVQKA
>NC_013939.1|WP_041223547.1|315392_317414_-|PAS-domain-S-box-protein
MSVERQEFFYIFTDLANKTTVAILIYQDNKIIFANPATSQITGYKNDELIGMNFWELVDDNFKEVVKKRGLERQRGLDSHHKYNVLVKRKDGKKRWVLLEGRTTIYRGRPAGLVTAIDIHEEKVSKQHLEQQAILLSILNKLDNKLKNVLTEEQLLNIVKKSIAKHPDITCFTFFLFDDNKNITNFTSYNLKKSLFNKYINKSYEELPGCFQQLKAKKTLVVSKGKLYSFCKGCILSKRNRGDFVVLKRLEYKENLLGFISITFQREHKTLEKFEHILLNEILNTIAKTIFELNQNLALNKLEENFKTFLENNIAAIAITTPQGSFIDCNQAFLNLFNYSSKEEVLKTPASSFYKDNKQRKYFIKLLKNKKVVKNIEMTYLDKNGNEVFVLENAVGKFEGDELKYIYSFLYDITFHRKIANHLINTEKLASINALTGNIAHEINNLLTPIATLSSHLLSDKDVNPKVKNILKLISDSAFKASNIINRVLEFSMVEKSAKKLVSPEKLLNDFIEIYKDNIPKNISLQIHCDSDIPAIEADYNQIFQVFRNIFTNSIEALPNGGNIKITLKKVSPETLPTEIQDFERNYIEFTFKDNGLGIKKEHLSKVFEPFYTTKQDKESLGLGLYSAYSIIKQHNGHIIIDSEENKGTEVKIYLPTILDAFNTTNEEHLKKQ
>NC_013939.1|WP_013007067.1|317801_318812_+|uroporphyrinogen-decarboxylase
MKNDLLLKVLDGEKVERPPIWLMRQAGRYMKEYRDVRSKVTFLELCKTPELACEVTLQPIRAFGLDAAIVFSDILIPIEPMGVELDFNPAPVIANPIRSKTDAEKLTLVDPYKDLNFVIETVKLLVSKLDVPLIGFSGAPFTLACYMVEGKGSKNFDVIKTFMRNDEDGYRILMEKLSDSTIKYLQAQIDNGCPVVQIFDTWAGVLSPYDYEKYVFPYVDYIINNLKNAKVIYFAKNGATFFNSLKKLKCDALGVDWSVNLEDYAKLTDDEFVLQGNMDPTLLFASQDKIREMTKTIINEGKNIKGHIFNLGHGILPQTPVENVEFLVKFVKGEVE
>NC_013939.1|WP_013007068.1|318811_319762_+|ferrochelatase
MDLLYVMYMGGPDNIDGIEEFLFNLFSDRDIIDFKIGGLQKYLAKIIAKSRSKKVAPEYIKMGCGSPQTKYLIKLLEKVKVYYKEITKRELETEIGMCYYKPYIEETASKLQNGDYENIYIMTMYPQYSYTTSGVCFKRLFNATNIKPINKSYKVIPFWHLSEEYNKCIVKRIKSASERLGVELENCHLLYSAHSLPEYTLSKGDVYVEQLKAQIDLICSMLGSVKNYELAFQSRTGPIKWLGPETKTVIESYVEKRVDNIIVVPISFVSDHIETLIELDEQYIKFAKENGLNIERIESLNDSDDFAKAVVNILRG
>NC_013939.1|WP_013007069.1|319764_320616_+|UbiA-family-prenyltransferase
MEKVISFFRMIKVEHTLFALPFAFTGAIIAAKGIPSIDKIFWIAVAMLGARSGAMGFNRVADAEIDAKNPRTANREIPAGKISKKEAIIYIIISFLLYFLAAYKLNPLCFKLSPIPVIIFILYSYTKRFTFLCHLILGIALGLAPMGAWVAITGSIDFRIVLLGVGVMFWVAGFDLIYAIQDIDFDREHNLFSIPRFIGIKNSIYLARAFHLIAFVLFLYAKFIFNLGILYLIGVILCGLFMIYEHSIIKPNDLSKLDMAFFNLNAYISLTIFVFTFFDVVVL
>NC_013939.1|WP_013007070.1|320612_321200_+|UbiX-family-flavin-prenyltransferase
MRKIFIGMTGASGSLYAGYFLHELCKLDDVKLFFTCTDDSVKNIYYEHNNLYNIDDFFSFYKIDRSKLTVYDYRDFAAPVSSGSFKVDDYVIIPASMGCIGRIANGISSNLIERAADVALKEKRRLTILFREAPLNSIHLENMLKLSNLGANIIPAAPAFYHKPEDIKDLIYFIIGKMFDIMNVEHNLFKRWKST

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Crispr_ID: NC_013939_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_013939_2

514731-516696

TypeI-B

Consensus_repeat	Method
GTTTCAATTCCTCATAGGCACTCTAAAAAC	CRISPRCasFinder
GTTTCAATTCCTCTTAGGCACTCTAAAAAC	CRT
GTTTCAATTCCTCTTAGGCACTCTAAAAAC	PILER-CR

29 spacers

cas3,cas5,cas7,cas8b1,cas6,cas2,cas1,cas4

The CRISPR arrays of NC_013939_2

>merge|NC_013939|2|514731-516696|CRISPRCasFinder,CRT,PILER-CR
AATTCAATTCCTCTTAGGCACTCTAAAAACCAGAAATAACAGGTTCAATCAAAGTATATGATAGAAAGTTTCAATTCCTCTTAGGCACTCTAAAAACAGAGTTAATTTTTTGTTGTACTCTTGTTCAAGGTACTGTTTCAATTCCTCTTAGGCACTCTAAAAACCAATCAAATCAAAAGCTGAGTATGTTGTATCTACTACAGTTTCAATTCCTCTTAGGCACTCTAAAAACATGTCCCAGGTTTTGTTTATTTGTTAGTGGATAGGAGTTTCAATTCCTCTTAGGCACTCTAAAAACCAAGTATTGATGCAGTAGCTTGTGAGGTGGGTGATGGTTTCAATTTCTCTTAGGCACTCTAAAAACGCTCCTCAAGACTCATCTTGACAATTTGACGACCATGTTTCAATTCCTCTTAGGCACTCTAAAAACAAGAGCTTGAGAAGGGACTCGAAAGGTTTCTTGCAGTCAGTTTCAATTCCTCTTAGGCACTCTAAAAACGTGAAAATCCATCTCGGGGATAAAGAGGAAATAAAAGAGTTTCAATTCCTCTTAGGCACTCTAAAAACTATTAAATCGTTTATACTTGATGTTGCAGATGTGCTGTTTCAATTCCTCATAGGCACTCTAAAAACTTTCAAAGAGAATAAAAAGATAATTCTAACTGAAGATGGTTTCAATTCCTCATAGGCACTCTAAAAACAATATTTATATGAAATCATTGAATCAAAAGATAACAAGTTTCAATTCCTCATAGGCACTCTAAAAACCTCACTGTGTTTTAGAAATTAGAAGCTTAAAAAATGGGTTTCAATTCCTCTTAGGCACTCTAAAAACTTTTTATACCATTGATTAGCTCGTTGTTCGATATTGTGTTTCAATTCCTCTTAGGCACTCTAAAAACCCGCTTATCGCTGCAGCTGTCAAAACGGGGAAAGATAGTTTCAATTCCTCTTAGGCACTCTAAAAACCTCTGCACAAAGCTTGTTATCAGGCTCGGCGAACAGGGGTTTCAATTCCTCTTAGGCACTCTAAAAACCTATAGCAATTTCATCCTTGTCTTTCATTAGGGAAGTTTCAATTCCTCTTAGGCACTCTAAAAACAAATATCTAAAGTTACTTTACGAATAGGAAACCATTGTTTCAATTCCTCTTAGGCACTCTAAAAACAAAGAAAACTAATGAAGGGGGTAGTTATGAAATATAAGTTTCAATTCCTCTTAGGCACTCTAAAAACATATTTATTGCATAAACGAAAATAATGATGGAAATGGTTTCAATTCCTCTTAGGCACTCTAAAAACATGGGCTTTTGTTGCCATAAAAGCATATCTATTTTGTTTCAATTCCTCTTAGGCACTCTAAAAACCCAACCCTTTTCCATAAATAGTTATATTACAGTCTCTGTTTCAATTCCTCTTAGGCACTCTAAAAACTACATCAGTTCAATCTCCCGTTGTTTTTCAATTGTTGTTTCAATTCCTCTTAGGCACTCTAAAAACAGAAAAGATTAATCAATTTGGGGTTACTGTTCAATTGTTTCAATTCCTCTTAGGCACTCTAAAAACTTTTAAAATTGTATCCACCATATTGGTCTTCAATGGCGTTTCAATTCCTCTTAGGCACTCTAAAAACTTGAACAAATTCTGCAAGGTTGGTCTGAACAAGATACGTTTCAATTCCTCTTAGGCACTCTAAAAACGAAAACATTCAGAAATGAACATTGTGAATGGTATTCGTTTCAATTCCTCTTAGGCACTCTAAAAACTTGACATAGAAGTTGAACAAGGAAGTGATACAAGTCTGTTTCAATTCCTCTTAGGCACTCTAAAAACATATATAACATCAGAATCTTTAAACCAACGCGGAAAAGTTTCAATTCCTCTTAGGCACTCTAAAAACTATATTATATAAAGAAAACAGACCATCCTTGTAGATAGTTTCAATTCCTCTTAGGCACTCTAAAAAC

>NC_013939|2|2|514731-516696|CRISPRCasFinder
AATTCAATTCCTCTTAGGCACTCTAAAAAC	CAGAAATAACAGGTTCAATCAAAGTATATGATAGAAA
GTTTCAATTCCTCTTAGGCACTCTAAAAAC	AGAGTTAATTTTTTGTTGTACTCTTGTTCAAGGTACT
GTTTCAATTCCTCTTAGGCACTCTAAAAAC	CAATCAAATCAAAAGCTGAGTATGTTGTATCTACTACA
GTTTCAATTCCTCTTAGGCACTCTAAAAAC	ATGTCCCAGGTTTTGTTTATTTGTTAGTGGATAGGA
GTTTCAATTCCTCTTAGGCACTCTAAAAAC	CAAGTATTGATGCAGTAGCTTGTGAGGTGGGTGATG
GTTTCAATTTCTCTTAGGCACTCTAAAAAC	GCTCCTCAAGACTCATCTTGACAATTTGACGACCAT
GTTTCAATTCCTCTTAGGCACTCTAAAAAC	AAGAGCTTGAGAAGGGACTCGAAAGGTTTCTTGCAGTCA
GTTTCAATTCCTCTTAGGCACTCTAAAAAC	GTGAAAATCCATCTCGGGGATAAAGAGGAAATAAAAGA
GTTTCAATTCCTCTTAGGCACTCTAAAAAC	TATTAAATCGTTTATACTTGATGTTGCAGATGTGCT
GTTTCAATTCCTCATAGGCACTCTAAAAAC	TTTCAAAGAGAATAAAAAGATAATTCTAACTGAAGATG
GTTTCAATTCCTCATAGGCACTCTAAAAAC	AATATTTATATGAAATCATTGAATCAAAAGATAACAA
GTTTCAATTCCTCATAGGCACTCTAAAAAC	CTCACTGTGTTTTAGAAATTAGAAGCTTAAAAAATGG
GTTTCAATTCCTCTTAGGCACTCTAAAAAC	TTTTTATACCATTGATTAGCTCGTTGTTCGATATTGT
GTTTCAATTCCTCTTAGGCACTCTAAAAAC	CCGCTTATCGCTGCAGCTGTCAAAACGGGGAAAGATA
GTTTCAATTCCTCTTAGGCACTCTAAAAAC	CTCTGCACAAAGCTTGTTATCAGGCTCGGCGAACAGGG
GTTTCAATTCCTCTTAGGCACTCTAAAAAC	CTATAGCAATTTCATCCTTGTCTTTCATTAGGGAA
GTTTCAATTCCTCTTAGGCACTCTAAAAAC	AAATATCTAAAGTTACTTTACGAATAGGAAACCATT
GTTTCAATTCCTCTTAGGCACTCTAAAAAC	AAAGAAAACTAATGAAGGGGGTAGTTATGAAATATAA
GTTTCAATTCCTCTTAGGCACTCTAAAAAC	ATATTTATTGCATAAACGAAAATAATGATGGAAATG
GTTTCAATTCCTCTTAGGCACTCTAAAAAC	ATGGGCTTTTGTTGCCATAAAAGCATATCTATTTT
GTTTCAATTCCTCTTAGGCACTCTAAAAAC	CCAACCCTTTTCCATAAATAGTTATATTACAGTCTCT
GTTTCAATTCCTCTTAGGCACTCTAAAAAC	TACATCAGTTCAATCTCCCGTTGTTTTTCAATTGTT
GTTTCAATTCCTCTTAGGCACTCTAAAAAC	AGAAAAGATTAATCAATTTGGGGTTACTGTTCAATT
GTTTCAATTCCTCTTAGGCACTCTAAAAAC	TTTTAAAATTGTATCCACCATATTGGTCTTCAATGGC
GTTTCAATTCCTCTTAGGCACTCTAAAAAC	TTGAACAAATTCTGCAAGGTTGGTCTGAACAAGATAC
GTTTCAATTCCTCTTAGGCACTCTAAAAAC	GAAAACATTCAGAAATGAACATTGTGAATGGTATTC
GTTTCAATTCCTCTTAGGCACTCTAAAAAC	TTGACATAGAAGTTGAACAAGGAAGTGATACAAGTCT
GTTTCAATTCCTCTTAGGCACTCTAAAAAC	ATATATAACATCAGAATCTTTAAACCAACGCGGAAAA
GTTTCAATTCCTCTTAGGCACTCTAAAAAC	TATATTATATAAAGAAAACAGACCATCCTTGTAGATA
GTTTCAATTCCTCTTAGGCACTCTAAAAAC

>NC_013939|2|1|514731-516696|CRT
AATTCAATTCCTCTTAGGCACTCTAAAAAC	CAGAAATAACAGGTTCAATCAAAGTATATGATAGAAA
GTTTCAATTCCTCTTAGGCACTCTAAAAAC	AGAGTTAATTTTTTGTTGTACTCTTGTTCAAGGTACT
GTTTCAATTCCTCTTAGGCACTCTAAAAAC	CAATCAAATCAAAAGCTGAGTATGTTGTATCTACTACA
GTTTCAATTCCTCTTAGGCACTCTAAAAAC	ATGTCCCAGGTTTTGTTTATTTGTTAGTGGATAGGA
GTTTCAATTCCTCTTAGGCACTCTAAAAAC	CAAGTATTGATGCAGTAGCTTGTGAGGTGGGTGATG
GTTTCAATTTCTCTTAGGCACTCTAAAAAC	GCTCCTCAAGACTCATCTTGACAATTTGACGACCAT
GTTTCAATTCCTCTTAGGCACTCTAAAAAC	AAGAGCTTGAGAAGGGACTCGAAAGGTTTCTTGCAGTCA
GTTTCAATTCCTCTTAGGCACTCTAAAAAC	GTGAAAATCCATCTCGGGGATAAAGAGGAAATAAAAGA
GTTTCAATTCCTCTTAGGCACTCTAAAAAC	TATTAAATCGTTTATACTTGATGTTGCAGATGTGCT
GTTTCAATTCCTCATAGGCACTCTAAAAAC	TTTCAAAGAGAATAAAAAGATAATTCTAACTGAAGATG
GTTTCAATTCCTCATAGGCACTCTAAAAAC	AATATTTATATGAAATCATTGAATCAAAAGATAACAA
GTTTCAATTCCTCATAGGCACTCTAAAAAC	CTCACTGTGTTTTAGAAATTAGAAGCTTAAAAAATGG
GTTTCAATTCCTCTTAGGCACTCTAAAAAC	TTTTTATACCATTGATTAGCTCGTTGTTCGATATTGT
GTTTCAATTCCTCTTAGGCACTCTAAAAAC	CCGCTTATCGCTGCAGCTGTCAAAACGGGGAAAGATA
GTTTCAATTCCTCTTAGGCACTCTAAAAAC	CTCTGCACAAAGCTTGTTATCAGGCTCGGCGAACAGGG
GTTTCAATTCCTCTTAGGCACTCTAAAAAC	CTATAGCAATTTCATCCTTGTCTTTCATTAGGGAA
GTTTCAATTCCTCTTAGGCACTCTAAAAAC	AAATATCTAAAGTTACTTTACGAATAGGAAACCATT
GTTTCAATTCCTCTTAGGCACTCTAAAAAC	AAAGAAAACTAATGAAGGGGGTAGTTATGAAATATAA
GTTTCAATTCCTCTTAGGCACTCTAAAAAC	ATATTTATTGCATAAACGAAAATAATGATGGAAATG
GTTTCAATTCCTCTTAGGCACTCTAAAAAC	ATGGGCTTTTGTTGCCATAAAAGCATATCTATTTT
GTTTCAATTCCTCTTAGGCACTCTAAAAAC	CCAACCCTTTTCCATAAATAGTTATATTACAGTCTCT
GTTTCAATTCCTCTTAGGCACTCTAAAAAC	TACATCAGTTCAATCTCCCGTTGTTTTTCAATTGTT
GTTTCAATTCCTCTTAGGCACTCTAAAAAC	AGAAAAGATTAATCAATTTGGGGTTACTGTTCAATT
GTTTCAATTCCTCTTAGGCACTCTAAAAAC	TTTTAAAATTGTATCCACCATATTGGTCTTCAATGGC
GTTTCAATTCCTCTTAGGCACTCTAAAAAC	TTGAACAAATTCTGCAAGGTTGGTCTGAACAAGATAC
GTTTCAATTCCTCTTAGGCACTCTAAAAAC	GAAAACATTCAGAAATGAACATTGTGAATGGTATTC
GTTTCAATTCCTCTTAGGCACTCTAAAAAC	TTGACATAGAAGTTGAACAAGGAAGTGATACAAGTCT
GTTTCAATTCCTCTTAGGCACTCTAAAAAC	ATATATAACATCAGAATCTTTAAACCAACGCGGAAAA
GTTTCAATTCCTCTTAGGCACTCTAAAAAC	TATATTATATAAAGAAAACAGACCATCCTTGTAGATA
GTTTCAATTCCTCTTAGGCACTCTAAAAAC

>NC_013939|2|1|514733-516696|PILER-CR
TTCAATTCCTCTTAGGCACTCTAAAAACCA	GAAATAACAGGTTCAATCAAAGTATATGATAGAAAGT
TTCAATTCCTCTTAGGCACTCTAAAAACAG	AGTTAATTTTTTGTTGTACTCTTGTTCAAGGTACTGT
TTCAATTCCTCTTAGGCACTCTAAAAACCA	ATCAAATCAAAAGCTGAGTATGTTGTATCTACTACAGT
TTCAATTCCTCTTAGGCACTCTAAAAACAT	GTCCCAGGTTTTGTTTATTTGTTAGTGGATAGGAGT
TTCAATTCCTCTTAGGCACTCTAAAAACCA	AGTATTGATGCAGTAGCTTGTGAGGTGGGTGATGGT
TTCAATTTCTCTTAGGCACTCTAAAAACGC	TCCTCAAGACTCATCTTGACAATTTGACGACCATGT
TTCAATTCCTCTTAGGCACTCTAAAAACAA	GAGCTTGAGAAGGGACTCGAAAGGTTTCTTGCAGTCAGT
TTCAATTCCTCTTAGGCACTCTAAAAACGT	GAAAATCCATCTCGGGGATAAAGAGGAAATAAAAGAGT
TTCAATTCCTCTTAGGCACTCTAAAAACTA	TTAAATCGTTTATACTTGATGTTGCAGATGTGCTGT
TTCAATTCCTCATAGGCACTCTAAAAACTT	TCAAAGAGAATAAAAAGATAATTCTAACTGAAGATGGT
TTCAATTCCTCATAGGCACTCTAAAAACAA	TATTTATATGAAATCATTGAATCAAAAGATAACAAGT
TTCAATTCCTCATAGGCACTCTAAAAACCT	CACTGTGTTTTAGAAATTAGAAGCTTAAAAAATGGGT
TTCAATTCCTCTTAGGCACTCTAAAAACTT	TTTATACCATTGATTAGCTCGTTGTTCGATATTGTGT
TTCAATTCCTCTTAGGCACTCTAAAAACCC	GCTTATCGCTGCAGCTGTCAAAACGGGGAAAGATAGT
TTCAATTCCTCTTAGGCACTCTAAAAACCT	CTGCACAAAGCTTGTTATCAGGCTCGGCGAACAGGGGT
TTCAATTCCTCTTAGGCACTCTAAAAACCT	ATAGCAATTTCATCCTTGTCTTTCATTAGGGAAGT
TTCAATTCCTCTTAGGCACTCTAAAAACAA	ATATCTAAAGTTACTTTACGAATAGGAAACCATTGT
TTCAATTCCTCTTAGGCACTCTAAAAACAA	AGAAAACTAATGAAGGGGGTAGTTATGAAATATAAGT
TTCAATTCCTCTTAGGCACTCTAAAAACAT	ATTTATTGCATAAACGAAAATAATGATGGAAATGGT
TTCAATTCCTCTTAGGCACTCTAAAAACAT	GGGCTTTTGTTGCCATAAAAGCATATCTATTTTGT
TTCAATTCCTCTTAGGCACTCTAAAAACCC	AACCCTTTTCCATAAATAGTTATATTACAGTCTCTGT
TTCAATTCCTCTTAGGCACTCTAAAAACTA	CATCAGTTCAATCTCCCGTTGTTTTTCAATTGTTGT
TTCAATTCCTCTTAGGCACTCTAAAAACAG	AAAAGATTAATCAATTTGGGGTTACTGTTCAATTGT
TTCAATTCCTCTTAGGCACTCTAAAAACTT	TTAAAATTGTATCCACCATATTGGTCTTCAATGGCGT
TTCAATTCCTCTTAGGCACTCTAAAAACTT	GAACAAATTCTGCAAGGTTGGTCTGAACAAGATACGT
TTCAATTCCTCTTAGGCACTCTAAAAACGA	AAACATTCAGAAATGAACATTGTGAATGGTATTCGT
TTCAATTCCTCTTAGGCACTCTAAAAACTT	GACATAGAAGTTGAACAAGGAAGTGATACAAGTCTGT
TTCAATTCCTCTTAGGCACTCTAAAAACAT	ATATAACATCAGAATCTTTAAACCAACGCGGAAAAGT
TTCAATTCCTCTTAGGCACTCTAAAAACTA	TATTATATAAAGAAAACAGACCATCCTTGTAGATAGT
TTCAATTCCTCTTAGGCACTCTAAAAAC

Protein	Signature genes	Signature genes Name	Protein_function
NC_013939.1\|WP_013007285.1\|521834_523511_-\|TIGR02556-family-CRISPR-associated-protein	cas8b1	cd09672_cas8b1_CAS-I-B	gnl\|CDD\|378190
NC_013939.1\|WP_013007277.1\|511215_512169_+\|iron-ABC-transporter-permease	unknown	unknown	gnl\|CDD\|376439
NC_013939.1\|WP_013007286.1\|523494_524271_-\|CRISPR-associated-endoribonuclease-Cas6	cas6	COG1583_cas6_CAS-I:CAS-III:CAS-IV	gnl\|CDD\|187889
NC_013939.1\|WP_013007289.1\|525584_526079_-\|CRISPR-associated-protein-Cas4	cas4	pfam01930_cas4_CAS-I	gnl\|CDD\|366863
NC_013939.1\|WP_041223572.1\|513921_514104_+\|hypothetical-protein	unknown	unknown	unknown
NC_013939.1\|WP_013007282.1\|519842_520535_-\|type-I-B-CRISPR-associated-protein-Cas5	cas5	cls001430_cas5_CAS-I-B	gnl\|CDD\|131641
NC_013939.1\|WP_013007279.1\|516926_519263_-\|CRISPR-associated-helicase/endonuclease-Cas3	cas3	COG1203_cas3_CAS-I	gnl\|CDD\|224124
NC_013939.1\|WP_013007280.1\|519249_519522_-\|type-II-toxin-antitoxin-system-mRNA-interferase-toxin,-RelE/StbE-family	unknown	unknown	gnl\|CDD\|225583
NC_013939.1\|WP_013007273.1\|506774_507626_+\|kinase/pyrophosphorylase	unknown	unknown	gnl\|CDD\|377080
NC_013939.1\|WP_013007287.1\|524315_524582_-\|CRISPR-associated-endonuclease-Cas2	cas2	cd09725_cas2_CAS-I:CAS-II:CAS-III:CAS-V	gnl\|CDD\|187856
NC_013939.1\|WP_013007281.1\|519522_519771_-\|type-II-toxin-antitoxin-system-Phd/YefM-family-antitoxin	unknown	unknown	gnl\|CDD\|376852
NC_013939.1\|WP_013007278.1\|512165_512975_+\|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|224045
NC_013939.1\|WP_013007276.1\|510697_511213_+\|cob(I)yrinic-acid-a,c-diamide-adenosyltransferase	unknown	unknown	gnl\|CDD\|376827
NC_013939.1\|WP_013007288.1\|524585_525578_-\|type-I-B-CRISPR-associated-endonuclease-Cas1	cas1	cd09722_cas1_CAS-I-B	gnl\|CDD\|274695
NC_013939.1\|WP_041223574.1\|514323_514506_+\|hypothetical-protein	unknown	unknown	unknown
NC_013939.1\|WP_013007275.1\|509876_510701_+\|ABC-transporter-substrate-binding-protein	unknown	unknown	gnl\|CDD\|238564
NC_013939.1\|WP_041223571.1\|512967_513762_+\|energy-transducer-TonB	unknown	unknown	gnl\|CDD\|223880
NC_013939.1\|WP_041223840.1\|520886_521783_-\|type-I-B-CRISPR-associated-protein-Cas7/Csh2	cas7	cd09690_cas7_CAS-I-B	gnl\|CDD\|274217
NC_013939.1\|WP_013007274.1\|507972_509877_+\|TonB-dependent-receptor	unknown	unknown	gnl\|CDD\|238657
NC_013939.1\|WP_013007272.1\|504796_506788_+\|NAD-dependent-DNA-ligase-LigA	unknown	unknown	gnl\|CDD\|236137

Protein	Function_ID	Function_description	E-value
NC_013939.1\|WP_013007285.1\|521834_523511_-\|TIGR02556-family-CRISPR-associated-protein	gnl\|CDD\|378190	pfam09484, Cas_TM1802, CRISPR-associated protein TM1802 (cas_TM1802). Clusters of short DNA repeats with non-homologous spacers, which are found at regular intervals in the genomes of phylogenetically distinct prokaryotic species, comprise a family with recognisable features. This family is known as CRISPR (short for Clustered, Regularly Interspaced Short Palindromic Repeats). A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins. This minor cas protein is found in at least five prokaryotic genomes: Methanosarcina mazei, Sulfurihydrogenibium azorense, Thermotoga maritima, Carboxydothermus hydrogenoformans, and Dictyoglomus thermophilum, the first of which is archaeal while the rest are bacterial.	1.27181e-140
NC_013939.1\|WP_013007277.1\|511215_512169_+\|iron-ABC-transporter-permease	gnl\|CDD\|376439	pfam01032, FecCD, FecCD transport family. This is a sub-family of bacterial binding protein-dependent transport systems family. This Pfam entry contains the inner components of this multicomponent transport system.	1.67001e-63
NC_013939.1\|WP_013007286.1\|523494_524271_-\|CRISPR-associated-endoribonuclease-Cas6	gnl\|CDD\|187889	cd09759, Cas6_I-A, CRISPR/Cas system-associated RAMP superfamily protein Cas6. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas6 is an endoribonuclease that generates crRNAs, predicted subunit of Cascade complex; RAMP superfamily protein; Possesses double RRM/ferredoxin fold.	3.32429e-33
NC_013939.1\|WP_013007289.1\|525584_526079_-\|CRISPR-associated-protein-Cas4	gnl\|CDD\|366863	pfam01930, Cas_Cas4, Domain of unknown function DUF83. This domain has no known function. The domain contains three conserved cysteines at its C-terminus.	1.50416e-62
NC_013939.1\|WP_013007282.1\|519842_520535_-\|type-I-B-CRISPR-associated-protein-Cas5	gnl\|CDD\|131641	TIGR02592, hypothetical_protein_CTC_01466, CRISPR-associated protein Cas5, subtype I-B/HMARI. This is a CRISPR-associated protein unique to the hmari subtype of cas genes and CRISPR repeat, which is the only subtype present in Haloarcula marismortui ATCC 43049. The hmari type, though uncommon, is also found in the Aquificae, Thermotogae, Firmicutes, and Dictyoglomi.	1.7578e-39
NC_013939.1\|WP_013007279.1\|516926_519263_-\|CRISPR-associated-helicase/endonuclease-Cas3	gnl\|CDD\|224124	COG1203, COG1203, CRISPR-associated helicase Cas3 [Defense mechanisms].	1.01531e-43
NC_013939.1\|WP_013007280.1\|519249_519522_-\|type-II-toxin-antitoxin-system-mRNA-interferase-toxin,-RelE/StbE-family	gnl\|CDD\|225583	COG3041, COG3041, Uncharacterized protein conserved in bacteria [Function unknown].	2.43482e-08
NC_013939.1\|WP_013007273.1\|506774_507626_+\|kinase/pyrophosphorylase	gnl\|CDD\|377080	pfam03618, Kinase-PPPase, Kinase/pyrophosphorylase. This family of regulatory proteins has ADP-dependent kinase and inorganic phosphate-dependent pyrophosphorylase activity.	4.7587e-132
NC_013939.1\|WP_013007287.1\|524315_524582_-\|CRISPR-associated-endonuclease-Cas2	gnl\|CDD\|187856	cd09725, Cas2_I_II_III, CRISPR/Cas system-associated protein Cas2. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas2 is present in majority of CRISPR/Cas systems along with Cas1; RNAse specific to U-rich regions; Possesses an RRM/ferredoxin fold.	1.46723e-29
NC_013939.1\|WP_013007281.1\|519522_519771_-\|type-II-toxin-antitoxin-system-Phd/YefM-family-antitoxin	gnl\|CDD\|376852	pfam02604, PhdYeFM_antitox, Antitoxin Phd_YefM, type II toxin-antitoxin system. Members of this family act as antitoxins in type II toxin-antitoxin systems. When bound to their toxin partners, they can bind DNA via the N-terminus and repress the expression of operons containing genes encoding the toxin and the antitoxin. This domain complexes with Txe toxins containing pfam06769, Fic/DOC toxins containing pfam02661 and YafO toxins containing pfam13957.	2.56022e-05
NC_013939.1\|WP_013007278.1\|512165_512975_+\|ABC-transporter-ATP-binding-protein	gnl\|CDD\|224045	COG1120, FepC, ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components [Inorganic ion transport and metabolism / Coenzyme metabolism].	6.05938e-100
NC_013939.1\|WP_013007276.1\|510697_511213_+\|cob(I)yrinic-acid-a,c-diamide-adenosyltransferase	gnl\|CDD\|376827	pfam02572, CobA_CobO_BtuR, ATP:corrinoid adenosyltransferase BtuR/CobO/CobP. This family consists of the BtuR, CobO, CobP proteins all of which are Cob(I)alamin adenosyltransferase, EC:2.5.1.17, involved in cobalamin (vitamin B12) biosynthesis. These enzymes catalyze the adenosylation reaction: ATP + cob(I)alamin + H2O <=> phosphate + diphosphate + adenosylcobalamin.	3.0248e-89
NC_013939.1\|WP_013007288.1\|524585_525578_-\|type-I-B-CRISPR-associated-endonuclease-Cas1	gnl\|CDD\|274695	TIGR03641, cas1_HMARI, CRISPR-associated endonuclease Cas1, subtype I-B/HMARI/TNEAP. The CRISPR-associated protein Cas1 is virtually universal to CRISPR systems. CRISPR, an acronym for Clustered Regularly Interspaced Short Palindromic Repeats, is prokaryotic immunity system for foreign DNA, mostly from phage. CRISPR systems belong to different subtypes, distinguished by both nature of the repeats, the makeup of the cohort of associated Cas proteins, and by molecular phylogeny within the more universal Cas proteins such as this one. This model is of type EXCEPTION and provides more specific information than the EQUIVALOG model TIGR00287. It describes Cas1 subgroup that includes Cas1 proteins of the related HMARI and TNEAP subtypes of CRISPR/Cas system.	1.4427e-154
NC_013939.1\|WP_013007275.1\|509876_510701_+\|ABC-transporter-substrate-binding-protein	gnl\|CDD\|238564	cd01144, BtuF, Cobalamin binding protein BtuF. These proteins have been shown to function as initial receptors in ABC transport of vitamin B12 (cobalamin) in eubacterial and some archaeal species. They belong to the TroA superfamily of helical backbone metal receptor proteins that share a distinct fold and ligand binding mechanism. A typical TroA protein is comprised of two globular subdomains connected by a single helix and can bind the metal ion in the cleft between these domains. In addition, these proteins sometimes have a low complexity region containing a metal-binding histidine-rich motif (repetitive HDH sequence).	6.09927e-41
NC_013939.1\|WP_041223571.1\|512967_513762_+\|energy-transducer-TonB	gnl\|CDD\|223880	COG0810, TonB, Periplasmic protein TonB, links inner and outer membranes [Cell envelope biogenesis, outer membrane].	2.31508e-14
NC_013939.1\|WP_041223840.1\|520886_521783_-\|type-I-B-CRISPR-associated-protein-Cas7/Csh2	gnl\|CDD\|274217	TIGR02590, hypothetical_protein_MM_0563, CRISPR-associated protein Cas7/Csh2, subtype I-B/HMARI. This model represents one of two closely related CRISPR-associated proteins that belong to the larger family of TIGR01595. Members are the Csh2 protein of the Hmari subtype of CRISPR/cas system. CRISPR stands for Clustered Regularly Interspaced Short Palindromic Repeats. The related model is TIGR02589, the Csd3 protein of the Dvulg CRISPR subtype.	5.44749e-88
NC_013939.1\|WP_013007274.1\|507972_509877_+\|TonB-dependent-receptor	gnl\|CDD\|238657	cd01347, ligand_gated_channel, TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel. Energy (proton-motive force) and TonB-dependent conformational alteration of channel (parts of plug, and loops 7 and 8) allow passage of ligand. FepA residues 12-18 form the TonB box, which mediates the interaction with the TonB-containing inner membrane complex. TonB preferentially interacts with ligand-bound receptors. Transport thru the channel may resemble passage thru an air lock. In this model, ligand binding leads to closure of the extracellular end of pore, then a TonB-mediated signal facillitates opening of the interior side of pore, deforming the N-terminal plug and allowing passage of the ligand to the periplasm. Such a mechanism would prevent the free diffusion of small molecules thru the pore.	5.97351e-56
NC_013939.1\|WP_013007272.1\|504796_506788_+\|NAD-dependent-DNA-ligase-LigA	gnl\|CDD\|236137	PRK07956, ligA, NAD-dependent DNA ligase LigA; Validated.	0

>NC_013939.1|WP_041223574.1|514323_514506_+|hypothetical-protein
MTRKKLLDKKISEKLSLDSEKDKPITFFGSRLLTDSEIESLRKKAEQADQFYKEFFSKQN
>NC_013939.1|WP_041223572.1|513921_514104_+|hypothetical-protein
MYSGDSFFYVIGMIIVAIIIFIIAREFNCWYWKINKRLQLLEEINQNLKELLELQKRQKG
>NC_013939.1|WP_041223571.1|512967_513762_+|energy-transducer-TonB
MNNYSQNRFLIISIFISLTLHGVILIKYKVFHINFFDNDKSITINFEFKRAEKVKNDVPEGKKAAKINNLNFQNNNSHKNKIFKKPDLVKKHKEIIKKKIKNNIQKTVAFIPDKQIEVKKSSVQKIDDVKIDKQGLASNNHINKDFTEESNKVVKQDVSLLQDKKNYKNEQKFFDSNKYFNYVLNYIRDNLPYPYLARKRGIEGSVKVKIWINEAGKVVKVELLQSSGFKLLDKNTKYFLTKLTLKEKPPYEVNFTLTLEYKLL
>NC_013939.1|WP_013007278.1|512165_512975_+|ABC-transporter-ATP-binding-protein
MSYILKVKNLCAGYENGFSLKDINFSMKKSEFLGLIGPNGSGKSTFLKTLIGTLKKYSGEIFIQDKKIESYSRKELSRLIAYVPQKIENVEITVIDYLKLGRLPYFDNFQFFESKKDLDVINYYISFFQIENLIDKYLFQLSGGEQQIVSIASALIQEPTLLLLDEPTAHLDINHQIQIMDILKILNQEKGVSIVIVLHDLNLAAEYCDNLVLLKNGHIAASGSPEDVLNYKTIEKVYDMVVVSMKNPISNKPFVLPVSKLLMDKYKNE
>NC_013939.1|WP_013007277.1|511215_512169_+|iron-ABC-transporter-permease
MDKKTFLKKIGILLIFLGLLFLLNVFYNYDLKKVDLKILQVIRLPRALLAISVGGILSVSAAVLQGVFRNPLVETYTLGISGGAGIGVALAISLGLNKIFGYYALPFFGFLGALAVFWLIYQFALRKRFFEVDKVLMIGVMISFISSALLMLILSLSKTESINNVIYWLMGSLDESDYFVIFLTLIVSFIILIVFGLISNRLNGFLLGVEKGSSLGIDIVGLTKLTVFLACFSCAFAVSSSGIIPFVGIVVPHILKAIYGNDFRFLVPASFISGAAFMLFADLVAKIIISPNELPVGVITGIIGGIIFINIYRKRLK
>NC_013939.1|WP_013007276.1|510697_511213_+|cob(I)yrinic-acid-a,c-diamide-adenosyltransferase
MKGMVHVYTGNGKGKTTAAFGLALRGIGAGKSVYIIQFIKSMEYSEIKAFKKYFPFVPIEQFGRGCFIINKPEKEDILEAKKGFERVKELLKRKDIDILILDEINIAIYYGMIDCAELIEQLKNRNQEMEVVITGRYAKKELIDFADLVTEMKEVKHYYNSGVKARDGIER
>NC_013939.1|WP_013007275.1|509876_510701_+|ABC-transporter-substrate-binding-protein
MRKVLFRAAFVQLFFFFLFLNSLFAEINRVVSVVPSITKQLIYFKAQETIVGCSSYCKLAKDTNVQIVGNIININVEKIYSLKPDIVFVSNMTDVRDVEKLKKLGIKAAVFSYPKSIEEFFTQVKEIGKLTGYQKAANKAINISKKLFAELSNRCNALKGKKVFMEIGVKPLYSVPKDTYLNDFLLRLGLINITGKLKDGIINREYVIKENPDIIMIMDMGYKAKEEISYWHKFKFLNAVKNNKILLLEADKVASPALPEFFEYFKKILYRMCK
>NC_013939.1|WP_013007274.1|507972_509877_+|TonB-dependent-receptor
MNRKIVVLFLLISFSIVNFVFANDKKIVIFGEKITESEVENKANVIVITKEDIDKINPQTVYDILETIPGVSVKSYDLKHSLVIMGGFDGEKGGLNNVIMLNGRRITNPDMSTPDLSLIPVDMIERVEVYLGGGSVLFGDRATGGAINIVTKKPYKNSFTVKADGGSYGYYNIYAEGVFANERYSFIINADKLGMEGYRDNSEFYSGTVSGQFSYYLDKLEITFDTLYNDQRYGLPGSLTESDIANYGRKHSNTPLDGGDDYSKSFGLKLSYDLSENSKIVFDSNIRQRNRSYYLYVKTNDELKTKIYQLYYDFKLNKKNYSNHLQVGVEYEKDNLETESTWSSSKLDRKRKAVYFYDTFSISKIFGEYGYRYSKLNDDYDTYDKSKDTSEKAYTGVIGYNITKNHKIYIKYDRSFRFPTTDEMIEYSFVQYDYVLNDSLDTQVDKTYEIGFKSDYKKYFVHLSVYKQVSNSEIFTNPTYVPYANTNFDTEKKVFNMNTGYDDNNILLMLSYNYIDSVITEDGYDDSFVPLVSKHTIKATAGYRTKAGFGVYYFVRYYSDYYVGNDYKNTYDKMDGYAISDLKLEYKKKNYEIYFKVNNLFNEQYYSYVNNYGYGNNYYPAPERNYMAGVKVKF
>NC_013939.1|WP_013007273.1|506774_507626_+|kinase/pyrophosphorylase
MKNIDVFLGKKGDDLKRIFIISDGTGQSAINLMRACLIQFEEQHVRLTVFSKVNTKEQIESILNQAREQKAFVAFTLVKKELRRYMHKLCHDYEIIHHDILGPPVEKLSNFLGAKPLENPNLLRRVDDKYFKRIEAIEFTINHDDGKNLKGLKEADIVILGLSRVSKTPTSFFLAQLGYKVVNIPIVPEIPLPKELFEIDQKKIVCLVMDPEVLQKVRMERMKHYKTTSNYTDLKRIFEELEFVYDLVKKNRQWHIVDTTNKSVEETAREIISCIYGREQELY
>NC_013939.1|WP_013007272.1|504796_506788_+|NAD-dependent-DNA-ligase-LigA
MDESILKEYQKLVDEINYHDYRYYVLNDPVISDYEYDQLYKRLKEIESKYPEIISPYSPTQRVGYAPVSNLKTVKHEVKMLSLDNTYNEGELKDFYNRVLKNLESVPSFVVEPKIDGAAVSLTYEDGILQIGATRGDGVTGEDVTHNVKTIKSIPLKIAVKGKLVVRGEVFLPKSEFERINDERVKNGLEPFANPRNAAAGTLKLLDPRIAAQRNLDIFIYSVDIGRKHDTHFDDLNYLKGLGFKVNPLIKKVESFEDIISHIENLGKMRDELDYEIDGAVIKVNEYSYQEQLGETIKYPRWAVAFKYPPELKTTVLKDVIFQVGRTGIITPVAVLEPVHISGSVVKRATLHNEDEIRRLDVKIGDTVFVEKSGEIIPKIIKVVKEKRTGKEKEIVFPEKCPVCNGLVRKENAYYVCLNPDCSAKLKASIIHFASRDAMDIKGLGEAIVERFVDLGFLKSIADIYTLDFEKIALLDGFGKKSAENLKKSIEDSKNRSFDRVLYALGIRHVGIKTARILTNHFKNIEKLQKATIEELVSIDEVGEIIAKSVYYTLRDENFLKLIERLKSYGLKFSMEDDKENKSEKLKGLKFVITGTLSKPRNYYVELIEKLGGEVSSSVSKKTDYVIVGEDPGSKYNKAISLGVKTINEEEFYKLIGGTDEKY
>NC_013939.1|WP_013007279.1|516926_519263_-|CRISPR-associated-helicase/endonuclease-Cas3
MKYINSKLHSHPDRLLEKHTSQVIELANKYYSEISINDKILKDILTIITFSHDIGKSTQFFQDYILGDKELKNKLETKHAHLGGIAGLFLTDRYLKSKNIDNPFLLSLSYILPKRHHSNLKDFLNDLVIEEEDIKILQTQINSIDKEKFKNFLQNVETCDKNLINFSFEEIDFQQIKQTLRKIRRFIRKLKDEKSIDYYINTVFMFSLILDADKSDVGIKTDKNILFKDIQIKPEIVDNFVKNLSFEETEIINLRKKAYKEVAEKEIDINQKIYTLTLPTGLGKTLISFKTALKIAEKLKKEKGINLKIIYCLPFLSIIEQNFSVFENVLKENDINLDSSILLKHHHLTGFSYKSKVDEFDYNTSRLLIEGWNSKIITTTFLQFFYSLIGNKNKMLRKFHRLANSVAILDEIQSIPHKYWLLIKEVLCRMAEKFNFYIIFSTATQPMIFEKKKYIELASKDYFEHIDRYDVFINKTQQTIELFYSNLNIEDNKTYLFIMNTVSSAKMLFEFLKKDFKDEIIFLSTHIIPKERLKRIKELKNHNKRIAVSTQLVEAGVDIDFDIVYRDFAPFDSLNQSAGRCNREGKKEKGKFYIVKLFDDKNNRSYSSYIYDSVLINATDEILEKEIYSEKEFIGLVNKYFEKIKQIKSDKVSLDMLEMLYTLKFSAEKEKDKIKSIEDFVLIKEDYYKEDVFIEIDNEAKKVWEEYTKIWQLQDLFERKKAFDSIKSDFYKFVVSVPIKDNPPPIENNFYFVPYENIHEYYDLETGFKVKGGLFFSF
>NC_013939.1|WP_013007280.1|519249_519522_-|type-II-toxin-antitoxin-system-mRNA-interferase-toxin,-RelE/StbE-family
MYSLVFTEIYLKREKEFLKKHKDLIPRYKKVLKLLELDPHHPSLRLHKLKGKFKDKYSVSITMSYRIILTFVIVKKEIVLIDIGHHDEVY
>NC_013939.1|WP_013007281.1|519522_519771_-|type-II-toxin-antitoxin-system-Phd/YefM-family-antitoxin
MILSANDLKTKGISFVEKLIKKYNEVFITVRGKKKFVILPVEEYEKLKEAELDKIIKEAEEDYKKGRYIKETAEEHFQRLGI
>NC_013939.1|WP_013007282.1|519842_520535_-|type-I-B-CRISPR-associated-protein-Cas5
MKVLVFDIWGDFGHFKKFYTTSSPLTFSVPPPTAVYGMLGAILGFGKNEYLQYLNVKTTKIAIQILNPIKKTRMTINLIDTKNSNSFHLIKSRTQIKTEFLRNPAYRFYVNINNEDLFNKLIQRVKNKETYYTLSLGLANLLANFKYIGAFKAEPTGNADFVNSAILSKNVENIEVEEGKKYFKEKLPIDMNQNREVLKYEDVIMELNGQKLEGNFKNCYKIEDKIVSFF
>NC_013939.1|WP_041223840.1|520886_521783_-|type-I-B-CRISPR-associated-protein-Cas7/Csh2
MIKNRREYLFLYDVSFANPNGDPNDENKPRIDEETGKNIVTDVRLKRTIRDYLKDFEGLEIFVREIADENGKIQDAKARAKDFENNPEKILNECIDVRLFGGTIPITTGKNKDSSITYTGAVQFNMGQSLHRVKLEYIKGTGAFASTAGKEQKTFREEWILPYSLIAFHGVANENAAKTTKLTDTDLEYLKKGMWEGTKNLITRSKNEQIPRLLIEVIYKNEVHSHIGELHRYIKLESEKADEELRSTDDFILNIDELIYALEEEADKIEKVLYKIDRNLRLNKDFSSEKINFEKIEI
>NC_013939.1|WP_013007285.1|521834_523511_-|TIGR02556-family-CRISPR-associated-protein
MLTAIKDLGEILLEKENKTPIDILIENPDSSGTYKVVWALEFDKDLNFQKLSVEEFKAESPYIYLYKRASGSNAPDFSPTSRVTEPEKTFTKKLLKWLEGHNNIIEIKNIYNELVKNKDEIIKKLEELNQQTKDNKILTIKIDGKYLYEIENPDFKKILLEDYLNKIKEISKKDAVCSVCGEKKEEVFTTSQIYKFYTLDKECYITGGFNKKEAWKNFPICEKCFLKVDFAKKFVEEHLKYNFYSKTYYLIPKMILNVPEALDEINEILTSEEKIQKLTNEQRKTITGDKEEILDIIKDYKDVVSFYFLFLKKDNAAERILLLIEDVFPSRIHFIYETKTKIDRIFEQNYTFAKLNEFLKEFDKLFFEVIDKIFRSGKLNFKTLIQIFNRKIRSDFLNNKNFNYTVIDALMNINFFEELCLINCEENKMEKTKFDKIFEKVGKSLNTPAKRGIFLLGALTQMLLNIQGQERESTPFFKNLKGLKMNEENIKGLLPKVINKLMEYERFDKGKQELTKEISKEFLAQEKFGLTIDEINFYFASGMALSKEVANIIYEKEE
>NC_013939.1|WP_013007286.1|523494_524271_-|CRISPR-associated-endoribonuclease-Cas6
MKIKLLFNSDNEYIILPIHHNYLLQSMFYNNLPTPLANFLHEIGFFYYKRQFKLFTFSKIQSKYFELIREKSKITKIKYKTPITIFISSAINDFTKNWGETFLKKENIFLGKNPLYLESIEVLQNPYFEEDFIIKTLSPITAYKTFENGKKYYRYYSPSEPEFQYLIKENLRKKFEIITGEEISEFPIEIQPIKTKKVLFKYKDFPIEAYEGTFKIKTIPELFKTVYDAGLGAKNSQGFGMVEILNNTIKREKYVDSY
>NC_013939.1|WP_013007287.1|524315_524582_-|CRISPR-associated-endonuclease-Cas2
MFIILVYDANEKRVQKFHKTCKKYLTWVQNSVFEGEITEANLRILTDELKDIMDENEDSVLIYKFRTKKYYERDSIGISKPSHEDLFF
>NC_013939.1|WP_013007288.1|524585_525578_-|type-I-B-CRISPR-associated-endonuclease-Cas1
MKKPIYIFNDGELKRKDNTLFFIKDNEKKTIPINAVSEIHVFGEIDINKRALEFLTKNKIPLYFYNYYGYYIGSYYPREYLNAGIIILKQAEFYLNKEERLFLAKSFVSGGLSNILKNLNYYKKTKLEKITPYIEQIEEKSKKINNKSSISSLMALEGEIRKIYYDAFNVILNFEDFYFDKRTKRPPENPINALISFGNSLIYTTILSQIYRTHLDPRIGYLHETNQRSFSLNLDLAEVFKPIIVDRVIFSLINKKQIQLKHFEQEIDFTYLNEKGRQIFIKLFEEKLATTINYKNIGKVSYRKLIRLECYKLYKHFLKEDIYKPFITNW
>NC_013939.1|WP_013007289.1|525584_526079_-|CRISPR-associated-protein-Cas4
MDTVNINGTLIWYYYICPREVWFIGHSIEADQENDFLALGRHIHDFYYKKQKKEFIIDNTIKIDILPGKKVIGEIKKSSKYLKSATMQIAFYLYFLKQKGINLSGELLFPEERKKKKIFLTKEIENELKNAISNINKILNMDKPPKATKIHYCKNCAYKEMCWS

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Crispr_ID: NC_013939_3

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_013939_3

526129-527564

TypeI-B

Consensus_repeat	Method
GTTTCAATTCCTCATAGGCACTCTAAAAAC	CRISPRCasFinder
GTTTCAATTCCTCATAGGCACTCTAAAAAC	CRT
GTTTCAATTCCTCATAGGCACTCTAAAAAC	PILER-CR

21 spacers

cas4,cas1,cas2,cas6,cas8b1,cas7,cas5,cas3

The CRISPR arrays of NC_013939_3

>merge|NC_013939|3|526129-527564|CRISPRCasFinder,CRT,PILER-CR
ACTTCAAATCCTTTAAGGCACTTTAAAAACAAAGAACTTGAGAAGGAAGTTTATATTGATCTACCTTGTTTCAAATCCTTTTAGGCACTCTAAAAACTCAACCAATCTATATTAGTCCGAATTATATTCATTTGAGTTTCAATTCCTCATAGGCACTCTAAAAACTGATGAATGAGGAAATACCAATTTCGCCTGATGATCGTTTCAATTCCTCATAGGCACTCTAAAAACAAAAACAAAAGATAAGGCAATCGCAAAACGCCTATTGTTTCAATTCCTCATAGGCACTCTAAAAACTTGATGAAGCTCAAAAAATATTCGATAGGAAATTTTAGTTTCAATTCCTCATAGGCACTCTAAAAACTAACAAATAGTGAATCAGATTCAGTTTACAAATGATGTTTCAATTCCTCATAGGCACTCTAAAAACTAACAAATAGTGAATCAGATTCAGTTTACAAATGATGTTTCAATTCCTCATAGGCACTCTAAAAACATAATAGGCATTACTGTAATAAATAAAGTAGTTAAAAGTTTCAATTCCTCATAGGCACTCTAAAAACGAAAAATTAGGAAAAGCACGCTAAAAAGCGTGCTTTTTGTTTCAATTCCTCATAGGCACTCTAAAAACTTGTCAATCCAAATATTACAGTTGTGCAATTTGCGCAACGTTTCAATTCCTCATAGGCACTCTAAAAACAATTGTACAAATCTGTAATTTTCTTTTTGTTGTTTAGGTTTCAATTCCTCATAGGCACTCTAAAAACTTGTCAAATAAATAACTAATGTAATTGTGCAAATCTGGTTTCAATTCCTCATAGGCACTCTAAAAACAGACTCAACGACGGTTTTATGGAGCATTATAGATGGTTGTTTCAATTCCTCATAGGCACTCTAAAAACGATGGTTTGACCTTCAAAACCTTGCGAACGAAATTATTGTTTCAATTCCTCATAGGCACTCTAAAAACTTCCAAAAAACTTGTGGGGTTGGAAGAAGCAGGAAAAGTTTCAATTCCTCATAGGCACTCTAAAAACTTGCAACCCTTCATGCTTTGAACTTTGTTCAAAGCGAAAGTTTCAATTCCTCATAGGCACTCTAAAAACAAGGGGCTCAAAGCGTGGAATAATAAAAGAGTTTTCGTTTCAATTCCTCATAGGCACTCTAAAAACTAATAGCTCTTCTTGGTCCGCTATTAACAGCAAAGTCGTTTCAATTCCTCATAGGCACTCTAAAAACGAACGCGCTCATATCTATGGACATCTTTTAAACCCGTTTCAATTCCTCATAGGCACTCTAAAAACATTTCTGGACTCTATGGACATAATGGACACTTTTTTGTTTCAATTCCTCATAGGCACTCTAAAAACAAAACCCGACGCCATTATTAATGTCATCGGGTTTTCGTTTCAATTCCTCATAGGCACTCTAAAAAC

>NC_013939|3|3|526129-527564|CRISPRCasFinder
ACTTCAAATCCTTTAAGGCACTTTAAAAAC	AAAGAACTTGAGAAGGAAGTTTATATTGATCTACCTT
GTTTCAAATCCTTTTAGGCACTCTAAAAAC	TCAACCAATCTATATTAGTCCGAATTATATTCATTTGA
GTTTCAATTCCTCATAGGCACTCTAAAAAC	TGATGAATGAGGAAATACCAATTTCGCCTGATGATC
GTTTCAATTCCTCATAGGCACTCTAAAAAC	AAAAACAAAAGATAAGGCAATCGCAAAACGCCTATT
GTTTCAATTCCTCATAGGCACTCTAAAAAC	TTGATGAAGCTCAAAAAATATTCGATAGGAAATTTTA
GTTTCAATTCCTCATAGGCACTCTAAAAAC	TAACAAATAGTGAATCAGATTCAGTTTACAAATGAT
GTTTCAATTCCTCATAGGCACTCTAAAAAC	TAACAAATAGTGAATCAGATTCAGTTTACAAATGAT
GTTTCAATTCCTCATAGGCACTCTAAAAAC	ATAATAGGCATTACTGTAATAAATAAAGTAGTTAAAA
GTTTCAATTCCTCATAGGCACTCTAAAAAC	GAAAAATTAGGAAAAGCACGCTAAAAAGCGTGCTTTTT
GTTTCAATTCCTCATAGGCACTCTAAAAAC	TTGTCAATCCAAATATTACAGTTGTGCAATTTGCGCAAC
GTTTCAATTCCTCATAGGCACTCTAAAAAC	AATTGTACAAATCTGTAATTTTCTTTTTGTTGTTTAG
GTTTCAATTCCTCATAGGCACTCTAAAAAC	TTGTCAAATAAATAACTAATGTAATTGTGCAAATCTG
GTTTCAATTCCTCATAGGCACTCTAAAAAC	AGACTCAACGACGGTTTTATGGAGCATTATAGATGGTT
GTTTCAATTCCTCATAGGCACTCTAAAAAC	GATGGTTTGACCTTCAAAACCTTGCGAACGAAATTATT
GTTTCAATTCCTCATAGGCACTCTAAAAAC	TTCCAAAAAACTTGTGGGGTTGGAAGAAGCAGGAAAA
GTTTCAATTCCTCATAGGCACTCTAAAAAC	TTGCAACCCTTCATGCTTTGAACTTTGTTCAAAGCGAAA
GTTTCAATTCCTCATAGGCACTCTAAAAAC	AAGGGGCTCAAAGCGTGGAATAATAAAAGAGTTTTC
GTTTCAATTCCTCATAGGCACTCTAAAAAC	TAATAGCTCTTCTTGGTCCGCTATTAACAGCAAAGTC
GTTTCAATTCCTCATAGGCACTCTAAAAAC	GAACGCGCTCATATCTATGGACATCTTTTAAACCC
GTTTCAATTCCTCATAGGCACTCTAAAAAC	ATTTCTGGACTCTATGGACATAATGGACACTTTTTT
GTTTCAATTCCTCATAGGCACTCTAAAAAC	AAAACCCGACGCCATTATTAATGTCATCGGGTTTTC
GTTTCAATTCCTCATAGGCACTCTAAAAAC

>NC_013939|3|2|526129-527564|CRT
ACTTCAAATCCTTTAAGGCACTTTAAAAAC	AAAGAACTTGAGAAGGAAGTTTATATTGATCTACCTT
GTTTCAAATCCTTTTAGGCACTCTAAAAAC	TCAACCAATCTATATTAGTCCGAATTATATTCATTTGA
GTTTCAATTCCTCATAGGCACTCTAAAAAC	TGATGAATGAGGAAATACCAATTTCGCCTGATGATC
GTTTCAATTCCTCATAGGCACTCTAAAAAC	AAAAACAAAAGATAAGGCAATCGCAAAACGCCTATT
GTTTCAATTCCTCATAGGCACTCTAAAAAC	TTGATGAAGCTCAAAAAATATTCGATAGGAAATTTTA
GTTTCAATTCCTCATAGGCACTCTAAAAAC	TAACAAATAGTGAATCAGATTCAGTTTACAAATGAT
GTTTCAATTCCTCATAGGCACTCTAAAAAC	TAACAAATAGTGAATCAGATTCAGTTTACAAATGAT
GTTTCAATTCCTCATAGGCACTCTAAAAAC	ATAATAGGCATTACTGTAATAAATAAAGTAGTTAAAA
GTTTCAATTCCTCATAGGCACTCTAAAAAC	GAAAAATTAGGAAAAGCACGCTAAAAAGCGTGCTTTTT
GTTTCAATTCCTCATAGGCACTCTAAAAAC	TTGTCAATCCAAATATTACAGTTGTGCAATTTGCGCAAC
GTTTCAATTCCTCATAGGCACTCTAAAAAC	AATTGTACAAATCTGTAATTTTCTTTTTGTTGTTTAG
GTTTCAATTCCTCATAGGCACTCTAAAAAC	TTGTCAAATAAATAACTAATGTAATTGTGCAAATCTG
GTTTCAATTCCTCATAGGCACTCTAAAAAC	AGACTCAACGACGGTTTTATGGAGCATTATAGATGGTT
GTTTCAATTCCTCATAGGCACTCTAAAAAC	GATGGTTTGACCTTCAAAACCTTGCGAACGAAATTATT
GTTTCAATTCCTCATAGGCACTCTAAAAAC	TTCCAAAAAACTTGTGGGGTTGGAAGAAGCAGGAAAA
GTTTCAATTCCTCATAGGCACTCTAAAAAC	TTGCAACCCTTCATGCTTTGAACTTTGTTCAAAGCGAAA
GTTTCAATTCCTCATAGGCACTCTAAAAAC	AAGGGGCTCAAAGCGTGGAATAATAAAAGAGTTTTC
GTTTCAATTCCTCATAGGCACTCTAAAAAC	TAATAGCTCTTCTTGGTCCGCTATTAACAGCAAAGTC
GTTTCAATTCCTCATAGGCACTCTAAAAAC	GAACGCGCTCATATCTATGGACATCTTTTAAACCC
GTTTCAATTCCTCATAGGCACTCTAAAAAC	ATTTCTGGACTCTATGGACATAATGGACACTTTTTT
GTTTCAATTCCTCATAGGCACTCTAAAAAC	AAAACCCGACGCCATTATTAATGTCATCGGGTTTTC
GTTTCAATTCCTCATAGGCACTCTAAAAAC

>NC_013939|3|2|526662-527564|PILER-CR
GTTTCAATTCCTCATAGGCACTCTAAAAAC	GAAAAATTAGGAAAAGCACGCTAAAAAGCGTGCTTTTT
GTTTCAATTCCTCATAGGCACTCTAAAAAC	TTGTCAATCCAAATATTACAGTTGTGCAATTTGCGCAAC
GTTTCAATTCCTCATAGGCACTCTAAAAAC	AATTGTACAAATCTGTAATTTTCTTTTTGTTGTTTAG
GTTTCAATTCCTCATAGGCACTCTAAAAAC	TTGTCAAATAAATAACTAATGTAATTGTGCAAATCTG
GTTTCAATTCCTCATAGGCACTCTAAAAAC	AGACTCAACGACGGTTTTATGGAGCATTATAGATGGTT
GTTTCAATTCCTCATAGGCACTCTAAAAAC	GATGGTTTGACCTTCAAAACCTTGCGAACGAAATTATT
GTTTCAATTCCTCATAGGCACTCTAAAAAC	TTCCAAAAAACTTGTGGGGTTGGAAGAAGCAGGAAAA
GTTTCAATTCCTCATAGGCACTCTAAAAAC	TTGCAACCCTTCATGCTTTGAACTTTGTTCAAAGCGAAA
GTTTCAATTCCTCATAGGCACTCTAAAAAC	AAGGGGCTCAAAGCGTGGAATAATAAAAGAGTTTTC
GTTTCAATTCCTCATAGGCACTCTAAAAAC	TAATAGCTCTTCTTGGTCCGCTATTAACAGCAAAGTC
GTTTCAATTCCTCATAGGCACTCTAAAAAC	GAACGCGCTCATATCTATGGACATCTTTTAAACCC
GTTTCAATTCCTCATAGGCACTCTAAAAAC	ATTTCTGGACTCTATGGACATAATGGACACTTTTTT
GTTTCAATTCCTCATAGGCACTCTAAAAAC	AAAACCCGACGCCATTATTAATGTCATCGGGTTTTC
GTTTCAATTCCTCATAGGCACTCTAAAAAC

Protein	Signature genes	Signature genes Name	Protein_function
NC_013939.1\|WP_161595863.1\|527870_528641_-\|RNA-pseudouridine-synthase	unknown	unknown	gnl\|CDD\|223638
NC_013939.1\|WP_013007285.1\|521834_523511_-\|TIGR02556-family-CRISPR-associated-protein	cas8b1	cd09672_cas8b1_CAS-I-B	gnl\|CDD\|378190
NC_013939.1\|WP_013007286.1\|523494_524271_-\|CRISPR-associated-endoribonuclease-Cas6	cas6	COG1583_cas6_CAS-I:CAS-III:CAS-IV	gnl\|CDD\|187889
NC_013939.1\|WP_013007295.1\|531868_532756_+\|complex-I-NDUFA9-subunit-family-protein	unknown	unknown	gnl\|CDD\|187579
NC_013939.1\|WP_013007298.1\|534193_537763_-\|pyruvate:ferredoxin-(flavodoxin)-oxidoreductase	unknown	unknown	gnl\|CDD\|131231
NC_013939.1\|WP_013007282.1\|519842_520535_-\|type-I-B-CRISPR-associated-protein-Cas5	cas5	cls001430_cas5_CAS-I-B	gnl\|CDD\|131641
NC_013939.1\|WP_013007299.1\|537995_539651_+\|AMP-binding-protein	unknown	unknown	gnl\|CDD\|236236
NC_013939.1\|WP_013007279.1\|516926_519263_-\|CRISPR-associated-helicase/endonuclease-Cas3	cas3	COG1203_cas3_CAS-I	gnl\|CDD\|224124
NC_013939.1\|WP_013007280.1\|519249_519522_-\|type-II-toxin-antitoxin-system-mRNA-interferase-toxin,-RelE/StbE-family	unknown	unknown	gnl\|CDD\|225583
NC_013939.1\|WP_013007292.1\|529322_529673_-\|CidA/LrgA-family-protein	unknown	unknown	gnl\|CDD\|377131
NC_013939.1\|WP_041223579.1\|529819_530491_+\|DNA-repair-protein-RadC	unknown	unknown	gnl\|CDD\|178801
NC_013939.1\|WP_013007287.1\|524315_524582_-\|CRISPR-associated-endonuclease-Cas2	cas2	cd09725_cas2_CAS-I:CAS-II:CAS-III:CAS-V	gnl\|CDD\|187856
NC_013939.1\|WP_013007281.1\|519522_519771_-\|type-II-toxin-antitoxin-system-Phd/YefM-family-antitoxin	unknown	unknown	gnl\|CDD\|376852
NC_013939.1\|WP_153801506.1\|528637_529330_-\|CidB/LrgB-family-autolysis-modulator	unknown	unknown	gnl\|CDD\|377236
NC_013939.1\|WP_013007294.1\|530487_531861_+\|DUF4139-domain-containing-protein	unknown	unknown	gnl\|CDD\|379285
NC_013939.1\|WP_013007296.1\|532883_533462_-\|orotate-phosphoribosyltransferase	unknown	unknown	gnl\|CDD\|273579
NC_013939.1\|WP_013007288.1\|524585_525578_-\|type-I-B-CRISPR-associated-endonuclease-Cas1	cas1	cd09722_cas1_CAS-I-B	gnl\|CDD\|274695
NC_013939.1\|WP_041223580.1\|533454_534150_-\|orotidine-5'-phosphate-decarboxylase	unknown	unknown	gnl\|CDD\|234695
NC_013939.1\|WP_041223840.1\|520886_521783_-\|type-I-B-CRISPR-associated-protein-Cas7/Csh2	cas7	cd09690_cas7_CAS-I-B	gnl\|CDD\|274217
NC_013939.1\|WP_013007289.1\|525584_526079_-\|CRISPR-associated-protein-Cas4	cas4	pfam01930_cas4_CAS-I	gnl\|CDD\|366863

Protein	Function_ID	Function_description	E-value
NC_013939.1\|WP_161595863.1\|527870_528641_-\|RNA-pseudouridine-synthase	gnl\|CDD\|223638	COG0564, RluA, Pseudouridylate synthases, 23S RNA-specific [Translation, ribosomal structure and biogenesis].	1.6064e-27
NC_013939.1\|WP_013007285.1\|521834_523511_-\|TIGR02556-family-CRISPR-associated-protein	gnl\|CDD\|378190	pfam09484, Cas_TM1802, CRISPR-associated protein TM1802 (cas_TM1802). Clusters of short DNA repeats with non-homologous spacers, which are found at regular intervals in the genomes of phylogenetically distinct prokaryotic species, comprise a family with recognisable features. This family is known as CRISPR (short for Clustered, Regularly Interspaced Short Palindromic Repeats). A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins. This minor cas protein is found in at least five prokaryotic genomes: Methanosarcina mazei, Sulfurihydrogenibium azorense, Thermotoga maritima, Carboxydothermus hydrogenoformans, and Dictyoglomus thermophilum, the first of which is archaeal while the rest are bacterial.	1.27181e-140
NC_013939.1\|WP_013007286.1\|523494_524271_-\|CRISPR-associated-endoribonuclease-Cas6	gnl\|CDD\|187889	cd09759, Cas6_I-A, CRISPR/Cas system-associated RAMP superfamily protein Cas6. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas6 is an endoribonuclease that generates crRNAs, predicted subunit of Cascade complex; RAMP superfamily protein; Possesses double RRM/ferredoxin fold.	3.32429e-33
NC_013939.1\|WP_013007295.1\|531868_532756_+\|complex-I-NDUFA9-subunit-family-protein	gnl\|CDD\|187579	cd05271, NDUFA9_like_SDR_a, NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, subunit 9, 39 kDa, (NDUFA9) -like, atypical (a) SDRs. This subgroup of extended SDR-like proteins are atypical SDRs. They have a glycine-rich NAD(P)-binding motif similar to the typical SDRs, GXXGXXG, and have the YXXXK active site motif (though not the other residues of the SDR tetrad). Members identified include NDUFA9 (mitochondrial) and putative nucleoside-diphosphate-sugar epimerase. Atypical SDRs generally lack the catalytic residues characteristic of the SDRs, and their glycine-rich NAD(P)-binding motif is often different from the forms normally seen in classical or extended SDRs. Atypical SDRs include biliverdin IX beta reductase (BVR-B,aka flavin reductase), NMRa (a negative transcriptional regulator of various fungi), progesterone 5-beta-reductase like proteins, phenylcoumaran benzylic ether and pinoresinol-lariciresinol reductases, phenylpropene synthases, eugenol synthase, triphenylmethane reductase, isoflavone reductases, and others. SDRs are a functionally diverse family of oxidoreductases that have a single domain with a structurally conserved Rossmann fold, an NAD(P)(H)-binding region, and a structurally diverse C-terminal region. Sequence identity between different SDR enzymes is typically in the 15-30% range; they catalyze a wide range of activities including the metabolism of steroids, cofactors, carbohydrates, lipids, aromatic compounds, and amino acids, and act in redox sensing. Classical SDRs have an TGXXX[AG]XG cofactor binding motif and a YXXXK active site motif, with the Tyr residue of the active site motif serving as a critical catalytic residue (Tyr-151, human 15-hydroxyprostaglandin dehydrogenase numbering). In addition to the Tyr and Lys, there is often an upstream Ser and/or an Asn, contributing to the active site; while substrate binding is in the C-terminal region, which determines specificity. The standard reaction mechanism is a 4-pro-S hydride transfer and proton relay involving the conserved Tyr and Lys, a water molecule stabilized by Asn, and nicotinamide. In addition to the Rossmann fold core region typical of all SDRs, extended SDRs have a less conserved C-terminal extension of approximately 100 amino acids, and typically have a TGXXGXXG cofactor binding motif. Complex (multidomain) SDRs such as ketoreductase domains of fatty acid synthase have a GGXGXXG NAD(P)-binding motif and an altered active site motif (YXXXN). Fungal type ketoacyl reductases have a TGXXXGX(1-2)G NAD(P)-binding motif.	1.18043e-67
NC_013939.1\|WP_013007298.1\|534193_537763_-\|pyruvate:ferredoxin-(flavodoxin)-oxidoreductase	gnl\|CDD\|131231	TIGR02176, pyruvate_flavodoxin/ferrodoxin_oxidoreductase, pyruvate:ferredoxin (flavodoxin) oxidoreductase, homodimeric. This model represents a single chain form of pyruvate:ferredoxin (or flavodoxin) oxidoreductase. This enzyme may transfer electrons to nitrogenase in nitrogen-fixing species. Portions of this protein are homologous to gamma subunit of the four subunit pyruvate:ferredoxin (flavodoxin) oxidoreductase.	0
NC_013939.1\|WP_013007282.1\|519842_520535_-\|type-I-B-CRISPR-associated-protein-Cas5	gnl\|CDD\|131641	TIGR02592, hypothetical_protein_CTC_01466, CRISPR-associated protein Cas5, subtype I-B/HMARI. This is a CRISPR-associated protein unique to the hmari subtype of cas genes and CRISPR repeat, which is the only subtype present in Haloarcula marismortui ATCC 43049. The hmari type, though uncommon, is also found in the Aquificae, Thermotogae, Firmicutes, and Dictyoglomi.	1.7578e-39
NC_013939.1\|WP_013007299.1\|537995_539651_+\|AMP-binding-protein	gnl\|CDD\|236236	PRK08315, PRK08315, AMP-binding domain protein; Validated.	0
NC_013939.1\|WP_013007279.1\|516926_519263_-\|CRISPR-associated-helicase/endonuclease-Cas3	gnl\|CDD\|224124	COG1203, COG1203, CRISPR-associated helicase Cas3 [Defense mechanisms].	1.01531e-43
NC_013939.1\|WP_013007280.1\|519249_519522_-\|type-II-toxin-antitoxin-system-mRNA-interferase-toxin,-RelE/StbE-family	gnl\|CDD\|225583	COG3041, COG3041, Uncharacterized protein conserved in bacteria [Function unknown].	2.43482e-08
NC_013939.1\|WP_013007292.1\|529322_529673_-\|CidA/LrgA-family-protein	gnl\|CDD\|377131	pfam03788, LrgA, LrgA family. This family is uncharacterized. It contains the protein LrgA that has been hypothesized to export murein hydrolases.	2.36352e-31
NC_013939.1\|WP_041223579.1\|529819_530491_+\|DNA-repair-protein-RadC	gnl\|CDD\|178801	PRK00024, PRK00024, DNA repair protein RadC.	1.99744e-58
NC_013939.1\|WP_013007287.1\|524315_524582_-\|CRISPR-associated-endonuclease-Cas2	gnl\|CDD\|187856	cd09725, Cas2_I_II_III, CRISPR/Cas system-associated protein Cas2. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas2 is present in majority of CRISPR/Cas systems along with Cas1; RNAse specific to U-rich regions; Possesses an RRM/ferredoxin fold.	1.46723e-29
NC_013939.1\|WP_013007281.1\|519522_519771_-\|type-II-toxin-antitoxin-system-Phd/YefM-family-antitoxin	gnl\|CDD\|376852	pfam02604, PhdYeFM_antitox, Antitoxin Phd_YefM, type II toxin-antitoxin system. Members of this family act as antitoxins in type II toxin-antitoxin systems. When bound to their toxin partners, they can bind DNA via the N-terminus and repress the expression of operons containing genes encoding the toxin and the antitoxin. This domain complexes with Txe toxins containing pfam06769, Fic/DOC toxins containing pfam02661 and YafO toxins containing pfam13957.	2.56022e-05
NC_013939.1\|WP_153801506.1\|528637_529330_-\|CidB/LrgB-family-autolysis-modulator	gnl\|CDD\|377236	pfam04172, LrgB, LrgB-like family. The two products of the lrgAB operon are potential membrane proteins, and LrgA and LrgB are both thought to control of murein hydrolase activity and penicillin tolerance.	4.35036e-88
NC_013939.1\|WP_013007294.1\|530487_531861_+\|DUF4139-domain-containing-protein	gnl\|CDD\|379285	pfam13598, DUF4139, Domain of unknown function (DUF4139). This family is usually found at the C-terminus of proteins.	1.54645e-21
NC_013939.1\|WP_013007296.1\|532883_533462_-\|orotate-phosphoribosyltransferase	gnl\|CDD\|273579	TIGR01367, Orotate_phosphoribosyltransferase, orotate phosphoribosyltransferase, Thermus family. This model represents a distinct clade of orotate phosphoribosyltransferases. Members include the experimentally determined example from Thermus aquaticus and additional examples from Caulobacter crescentus, Helicobacter pylori, Mesorhizobium loti, and related species. [Purines, pyrimidines, nucleosides, and nucleotides, Pyrimidine ribonucleotide biosynthesis].	8.88788e-75
NC_013939.1\|WP_013007288.1\|524585_525578_-\|type-I-B-CRISPR-associated-endonuclease-Cas1	gnl\|CDD\|274695	TIGR03641, cas1_HMARI, CRISPR-associated endonuclease Cas1, subtype I-B/HMARI/TNEAP. The CRISPR-associated protein Cas1 is virtually universal to CRISPR systems. CRISPR, an acronym for Clustered Regularly Interspaced Short Palindromic Repeats, is prokaryotic immunity system for foreign DNA, mostly from phage. CRISPR systems belong to different subtypes, distinguished by both nature of the repeats, the makeup of the cohort of associated Cas proteins, and by molecular phylogeny within the more universal Cas proteins such as this one. This model is of type EXCEPTION and provides more specific information than the EQUIVALOG model TIGR00287. It describes Cas1 subgroup that includes Cas1 proteins of the related HMARI and TNEAP subtypes of CRISPR/Cas system.	1.4427e-154
NC_013939.1\|WP_041223580.1\|533454_534150_-\|orotidine-5'-phosphate-decarboxylase	gnl\|CDD\|234695	PRK00230, PRK00230, orotidine-5'-phosphate decarboxylase.	2.96789e-102
NC_013939.1\|WP_041223840.1\|520886_521783_-\|type-I-B-CRISPR-associated-protein-Cas7/Csh2	gnl\|CDD\|274217	TIGR02590, hypothetical_protein_MM_0563, CRISPR-associated protein Cas7/Csh2, subtype I-B/HMARI. This model represents one of two closely related CRISPR-associated proteins that belong to the larger family of TIGR01595. Members are the Csh2 protein of the Hmari subtype of CRISPR/cas system. CRISPR stands for Clustered Regularly Interspaced Short Palindromic Repeats. The related model is TIGR02589, the Csd3 protein of the Dvulg CRISPR subtype.	5.44749e-88
NC_013939.1\|WP_013007289.1\|525584_526079_-\|CRISPR-associated-protein-Cas4	gnl\|CDD\|366863	pfam01930, Cas_Cas4, Domain of unknown function DUF83. This domain has no known function. The domain contains three conserved cysteines at its C-terminus.	1.50416e-62

>NC_013939.1|WP_013007289.1|525584_526079_-|CRISPR-associated-protein-Cas4
MDTVNINGTLIWYYYICPREVWFIGHSIEADQENDFLALGRHIHDFYYKKQKKEFIIDNTIKIDILPGKKVIGEIKKSSKYLKSATMQIAFYLYFLKQKGINLSGELLFPEERKKKKIFLTKEIENELKNAISNINKILNMDKPPKATKIHYCKNCAYKEMCWS
>NC_013939.1|WP_013007288.1|524585_525578_-|type-I-B-CRISPR-associated-endonuclease-Cas1
MKKPIYIFNDGELKRKDNTLFFIKDNEKKTIPINAVSEIHVFGEIDINKRALEFLTKNKIPLYFYNYYGYYIGSYYPREYLNAGIIILKQAEFYLNKEERLFLAKSFVSGGLSNILKNLNYYKKTKLEKITPYIEQIEEKSKKINNKSSISSLMALEGEIRKIYYDAFNVILNFEDFYFDKRTKRPPENPINALISFGNSLIYTTILSQIYRTHLDPRIGYLHETNQRSFSLNLDLAEVFKPIIVDRVIFSLINKKQIQLKHFEQEIDFTYLNEKGRQIFIKLFEEKLATTINYKNIGKVSYRKLIRLECYKLYKHFLKEDIYKPFITNW
>NC_013939.1|WP_013007287.1|524315_524582_-|CRISPR-associated-endonuclease-Cas2
MFIILVYDANEKRVQKFHKTCKKYLTWVQNSVFEGEITEANLRILTDELKDIMDENEDSVLIYKFRTKKYYERDSIGISKPSHEDLFF
>NC_013939.1|WP_013007286.1|523494_524271_-|CRISPR-associated-endoribonuclease-Cas6
MKIKLLFNSDNEYIILPIHHNYLLQSMFYNNLPTPLANFLHEIGFFYYKRQFKLFTFSKIQSKYFELIREKSKITKIKYKTPITIFISSAINDFTKNWGETFLKKENIFLGKNPLYLESIEVLQNPYFEEDFIIKTLSPITAYKTFENGKKYYRYYSPSEPEFQYLIKENLRKKFEIITGEEISEFPIEIQPIKTKKVLFKYKDFPIEAYEGTFKIKTIPELFKTVYDAGLGAKNSQGFGMVEILNNTIKREKYVDSY
>NC_013939.1|WP_013007285.1|521834_523511_-|TIGR02556-family-CRISPR-associated-protein
MLTAIKDLGEILLEKENKTPIDILIENPDSSGTYKVVWALEFDKDLNFQKLSVEEFKAESPYIYLYKRASGSNAPDFSPTSRVTEPEKTFTKKLLKWLEGHNNIIEIKNIYNELVKNKDEIIKKLEELNQQTKDNKILTIKIDGKYLYEIENPDFKKILLEDYLNKIKEISKKDAVCSVCGEKKEEVFTTSQIYKFYTLDKECYITGGFNKKEAWKNFPICEKCFLKVDFAKKFVEEHLKYNFYSKTYYLIPKMILNVPEALDEINEILTSEEKIQKLTNEQRKTITGDKEEILDIIKDYKDVVSFYFLFLKKDNAAERILLLIEDVFPSRIHFIYETKTKIDRIFEQNYTFAKLNEFLKEFDKLFFEVIDKIFRSGKLNFKTLIQIFNRKIRSDFLNNKNFNYTVIDALMNINFFEELCLINCEENKMEKTKFDKIFEKVGKSLNTPAKRGIFLLGALTQMLLNIQGQERESTPFFKNLKGLKMNEENIKGLLPKVINKLMEYERFDKGKQELTKEISKEFLAQEKFGLTIDEINFYFASGMALSKEVANIIYEKEE
>NC_013939.1|WP_041223840.1|520886_521783_-|type-I-B-CRISPR-associated-protein-Cas7/Csh2
MIKNRREYLFLYDVSFANPNGDPNDENKPRIDEETGKNIVTDVRLKRTIRDYLKDFEGLEIFVREIADENGKIQDAKARAKDFENNPEKILNECIDVRLFGGTIPITTGKNKDSSITYTGAVQFNMGQSLHRVKLEYIKGTGAFASTAGKEQKTFREEWILPYSLIAFHGVANENAAKTTKLTDTDLEYLKKGMWEGTKNLITRSKNEQIPRLLIEVIYKNEVHSHIGELHRYIKLESEKADEELRSTDDFILNIDELIYALEEEADKIEKVLYKIDRNLRLNKDFSSEKINFEKIEI
>NC_013939.1|WP_013007282.1|519842_520535_-|type-I-B-CRISPR-associated-protein-Cas5
MKVLVFDIWGDFGHFKKFYTTSSPLTFSVPPPTAVYGMLGAILGFGKNEYLQYLNVKTTKIAIQILNPIKKTRMTINLIDTKNSNSFHLIKSRTQIKTEFLRNPAYRFYVNINNEDLFNKLIQRVKNKETYYTLSLGLANLLANFKYIGAFKAEPTGNADFVNSAILSKNVENIEVEEGKKYFKEKLPIDMNQNREVLKYEDVIMELNGQKLEGNFKNCYKIEDKIVSFF
>NC_013939.1|WP_013007281.1|519522_519771_-|type-II-toxin-antitoxin-system-Phd/YefM-family-antitoxin
MILSANDLKTKGISFVEKLIKKYNEVFITVRGKKKFVILPVEEYEKLKEAELDKIIKEAEEDYKKGRYIKETAEEHFQRLGI
>NC_013939.1|WP_013007280.1|519249_519522_-|type-II-toxin-antitoxin-system-mRNA-interferase-toxin,-RelE/StbE-family
MYSLVFTEIYLKREKEFLKKHKDLIPRYKKVLKLLELDPHHPSLRLHKLKGKFKDKYSVSITMSYRIILTFVIVKKEIVLIDIGHHDEVY
>NC_013939.1|WP_013007279.1|516926_519263_-|CRISPR-associated-helicase/endonuclease-Cas3
MKYINSKLHSHPDRLLEKHTSQVIELANKYYSEISINDKILKDILTIITFSHDIGKSTQFFQDYILGDKELKNKLETKHAHLGGIAGLFLTDRYLKSKNIDNPFLLSLSYILPKRHHSNLKDFLNDLVIEEEDIKILQTQINSIDKEKFKNFLQNVETCDKNLINFSFEEIDFQQIKQTLRKIRRFIRKLKDEKSIDYYINTVFMFSLILDADKSDVGIKTDKNILFKDIQIKPEIVDNFVKNLSFEETEIINLRKKAYKEVAEKEIDINQKIYTLTLPTGLGKTLISFKTALKIAEKLKKEKGINLKIIYCLPFLSIIEQNFSVFENVLKENDINLDSSILLKHHHLTGFSYKSKVDEFDYNTSRLLIEGWNSKIITTTFLQFFYSLIGNKNKMLRKFHRLANSVAILDEIQSIPHKYWLLIKEVLCRMAEKFNFYIIFSTATQPMIFEKKKYIELASKDYFEHIDRYDVFINKTQQTIELFYSNLNIEDNKTYLFIMNTVSSAKMLFEFLKKDFKDEIIFLSTHIIPKERLKRIKELKNHNKRIAVSTQLVEAGVDIDFDIVYRDFAPFDSLNQSAGRCNREGKKEKGKFYIVKLFDDKNNRSYSSYIYDSVLINATDEILEKEIYSEKEFIGLVNKYFEKIKQIKSDKVSLDMLEMLYTLKFSAEKEKDKIKSIEDFVLIKEDYYKEDVFIEIDNEAKKVWEEYTKIWQLQDLFERKKAFDSIKSDFYKFVVSVPIKDNPPPIENNFYFVPYENIHEYYDLETGFKVKGGLFFSF
>NC_013939.1|WP_161595863.1|527870_528641_-|RNA-pseudouridine-synthase
MKLVDYLSQQFNISKRLAKKYIKEKKVLIDGKFAKENLEITNIENHHISLNIDIKKIEYNLDEFIISNYENVIFLYKPPFMHTERHKLEDSLTISDIVSEHFKEYKLISRLDFETDGVIAAIKDGYKPENVLKKYLAVVIGNFPEDTIVFNKIVYKKRKKVKVLEEIDLEHLSNIKVINSDKNYSLLEITIFKATRHQIRAHLSFLGFPILGDTLYGDKQYKRLMLSCIYTKIDNFEAHSPKKENFIKEYQNLISV
>NC_013939.1|WP_153801506.1|528637_529330_-|CidB/LrgB-family-autolysis-modulator
MIENPIFSVMITFLVFYLASKLYNKYRFILFNPVLISITSLILLLKLINLDYHTYFKGAKIISFFLGPSVVALGVPLYLQFEEIKKRGISIIISIIIGSIVGILSAALTAKLLGASKVVVASIAPKSVTTPIAMGISKKIGGIPSLTAAIVIATGVLGAVIGPAFLKLTGIKNKVAVGLAIGSASHGIGTARAFEEGELEGASSSLAICLNGIATAIFTPIIFYIIYKLL
>NC_013939.1|WP_013007292.1|529322_529673_-|CidA/LrgA-family-protein
MVKSLTIIFLYLFIGDTISTLLNIPIPGNVIGMILLTISLKTNLIKLESVKPAADVLVKNMAFLFVPPGVGIMIYFDLIKKEFIPIVISYFFSTLAVLFIVGKVQQIMDKKNESNN
>NC_013939.1|WP_041223579.1|529819_530491_+|DNA-repair-protein-RadC
MKKEKPHYLGHRKRLKERFVNNPSSLADYEIVELLLGYVVRGKDVKPQAKNILAHVGGIQNIFKISDDIEGVGSETVLFFNIIKDLFRRCEYSNLRENETILNSPTAVFKFLKFEVGFDDVEKLIAVFLDSKGRIKEYKVLSSGSVNESYFPPKELAKQALVRDAVAVILAHNHPSGNLKPSQSDIRYTKNVKNALELVDIALVDHIIVTKNGFLSFKQEELL
>NC_013939.1|WP_013007294.1|530487_531861_+|DUF4139-domain-containing-protein
MNRLFVVCLMLILFATNLFAAKVDIYRDFVFYETTLKNGFIGFNKDVDVRCNGKSVNLVTENTLKLKCFLCDLYNKKNELTKESEKLSSELKLIDSTIKNVKLNSNEFLQFNIKVADEISNIKSKQQDLLYEINKINNLFSKSAPDNVPYFVQDENCSLVKMKFSGVSFNIVNQLNVENIAGDKAKLRIIKKAKIVNKSGVDIVADEAKLMFKSSSSFQGELSFNPWVVNIFEPFKRFLKSKSVQKSDVFESKEEIVDKGNREYLIKNFVLPANGKEKDFILNSAVKIGDYELITYPYLNKNVFREISFELPFDLESNSWTVSIGDEQFSNITGKQVKNRYKLLAGKLYDVKVERKRILDFEESAGFFGNKKRINDGYIITLTNISNINSYSLKVVDRVPVSKNEKIEVKDVKVSEDKCSINSEGKVECNIVLPPNKSIDIKVTFTILYDKDVEITY
>NC_013939.1|WP_013007295.1|531868_532756_+|complex-I-NDUFA9-subunit-family-protein
MKIFLTGGTGFVGTEILKYALSKDYEVTLLVRNPDKVKVKNDRIDIVVGDVLKPKTYLDKLNNVDCVVHLVGIIREIPKEGVTFQRYHFEATKMIVDAAKEGDVKRFIHMSANGARSEAITDYHKTKYLAEEYVRNSGLTYTIFKPSVIYGPGDSFINMLNDFLKKTPVFSYFGDGSYSMQPVYVADVAKIFVDAIENSDTFNKTFTVCGPEVLSYKELLRLICEVTNRKRLFIPVPEFIISFMITLFGKFQWFPLTRDQFEMLREGNTCENMEIYKLLQFEPKNIKDTLKKYLK
>NC_013939.1|WP_013007296.1|532883_533462_-|orotate-phosphoribosyltransferase
MDKNEILEIYKRHNALLKGHFLLSSGLHSDTYLQSALVMQYPVIAEEIIKELVKDIYHLNFVTVVSPAIGGIRFGYELARLLKKRAIFTERVDGKMTLRRGFTLEKGEKVIIAEDVVTTGKSTKECIDAVLEHGAEVVAICSLIDRSNGNAKFDYEFYPLLRINVETYEPENCPLCKQGVPIEKPGSRFLKK
>NC_013939.1|WP_041223580.1|533454_534150_-|orotidine-5'-phosphate-decarboxylase
MKPEIIVALDFSDFDDGKNIVETLDKEITFYKIGLEAYLSIGEKLIDYLVSKNKKVFLDLKFHDIPNTVKKAALAAAKKGVFMFNLHIQGGYDMIKETVAAVKSINSDVLIIGVTLLTSLDENYLNQYNINFNNSADYVLHLAKIGREAGLDGVVSSAKETPLIKKHLGEEFLTITPGIRLATNNIDDQKRVVTPKDAKKMGTDFMVIGRPITQSQDPKYTVKLIKEELNG
>NC_013939.1|WP_013007298.1|534193_537763_-|pyruvate:ferredoxin-(flavodoxin)-oxidoreductase
MSQRKYVNVDGNTAAAYVAHATNEVIAIYPITPSSVMGELADEMSAKGQKNIWGTVPKVIEMQSEGGAAGACHGSLSAGALTTTFTASQGLLLMIPNMYKIAGELTPTVFHVSARAVATHALSIFGDHSDVMACRQTGWALLASNNPQEVMDFALIAQASTLESRVPFLHFFDGFRTSHEIQKIEQLSHDDMRVMIDDELVRKHKERALNPEKPVIKGTSQNPDVFFQSREAVNKYYEKVPEIVQKQMDKFFELTGRRYNLVDYVGAPDAEKVIVIMGSGADVTHETVEYLNSQGEKVGVIKIRLYRPFPLEAFINALPKTVKKIAVLDRTKEPGSLGEPLYLDVRTAIGEAMQKKMVNFDRYPVIVGGRYGLGSKDFTPAMVKAVFDNLDKDEPINGFSVGIKDDVTFKSLDYDPNWLTPQDDVFNGMFYGLGSDGTVGANKNSAKIIGELTDNFVQAYFVYDSKKSGSMTVSHVRFGKKPIRSSYLIQEADFVACHNFSFLEQYEILKPLKKGGIFLLNSIYTKDEVWDKLPKEVQEQIIEKEAKFYVINANKIAEEIGLGGRVNVILQTAFFKISNVIPFDKAVDAIKDAIKKTYGKYGDEVVNMNIKAVEAGMNEVYEVNYPKQITSNTKMHKYIDNPDAPEIVRKAISKMIAMEGDDVPVSWLPDDGTYPTGTSKYEKRNIALNVPEWDPEVCIQCGICSFVCPHATIRMKVYDPKYLENAPETFKAVDAKGKEFAGMKFTIQVSVEDCTGCGACVYNCPAKSKTDPTKKAINMVPQPPIREQESKNWEFFLTIPDLDYSKYNKATLKGSQLAPHLFEFSGACAGCGETPYVRLVTHLFGDRAIIANATGCSSIYGGNLPTTPYTKRADGRGPAWSNSLFEDNAEFGLGMSLAVEKFKQQATELLTELKDKVGADLAEEILNADQSDQVGVEKQRERVAKLKEILKGLDDDKAKLLYDVADYLIKKSVWIIGGDGWAYDIGYGGLDHVLAQKNNVNILVLDTEVYSNTGGQSSKATNIGAFAKFAFSGKENPKKDLGMMAMSYGHVYVAQVSLSNPAQCIKAFVEAESYDGPSIIIANCHCIAHGIDMSKGVEHQRLAVQSGYWLLYRFDPRLTEQGKNPLQLDTKELKKSVSEFLKAENRFRAVAKMFPERAKMLAEFLDETIKRRFSIYKQLSTKMECSEEN
>NC_013939.1|WP_013007299.1|537995_539651_+|AMP-binding-protein
MKDFSFIEQTIGDYLKYIAKEYSDNEAVVYPFRNLRMTYRELDEYTDKLAYALLKLGVKKGDHVAIWANNIPEWIYLLFATAKIGAVLVTVNTLYRERELEYLLKQSDSKFLFLVEKYKTLNYVETLYNIYPELKESKKSDKFPLLEKVIIFDERQFDGIMKFSDLVKMGDDIDYKKLNEVMNSLHFDDVINMQYTSGTTGFPKGVMLTHYNILNNAYAIGHVMNFTDKDRLCIPVPFFHCFGLVLSILVCLTHGATMVPVENFNPIEVLKTVEKERCTALHGVPTMFISELQVLEHEKFDISSLRTGIMAGSPCPVEVMRKVMEVMNMSEITIVYGQTEASPGITQTRVDDDIEKRVATVGKELPGVEVKIVDPTTGKECPPNVAGELCARGYNVMKGYYKMEEATKKAIDEDGWLHTGDLALKTEDGYYVITGRIKDMIIRGGENIYPKEIEDFLYTYDAIEDVQIVGVPDKKYGEEVMAFIKLKPKYRGKVTPDDIRAFCKGKIADYKIPKYIEFVDEYPMTASGKIQKYKLREMAIDKLNLEPVLNK

You can click texts colored in the table to view more detailed information

Click the colored protein region to show detailed information

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NC_013939_2	2.12\|515499\|37\|NC_013939\|CRISPRCasFinder,CRT	515499-515535	37	NZ_CP053952	Bacillus cereus strain FDAARGOS_798 plasmid unnamed1, complete sequence	10513-10549	10	0.73
NC_013939_2	2.12\|515499\|37\|NC_013939\|CRISPRCasFinder,CRT	515499-515535	37	NZ_CP053949	Bacillus cereus strain FDAARGOS_799 plasmid unnamed1, complete sequence	140663-140699	10	0.73
NC_013939_2	2.41\|515501\|37\|NC_013939\|PILER-CR	515501-515537	37	NZ_CP053952	Bacillus cereus strain FDAARGOS_798 plasmid unnamed1, complete sequence	10513-10549	10	0.73
NC_013939_2	2.41\|515501\|37\|NC_013939\|PILER-CR	515501-515537	37	NZ_CP053949	Bacillus cereus strain FDAARGOS_799 plasmid unnamed1, complete sequence	140663-140699	10	0.73
NC_013939_3	3.9\|526692\|38\|NC_013939\|CRISPRCasFinder,CRT,PILER-CR	526692-526729	38	EU409559	Lactobacillus phage JCL1032, complete genome	49224-49261	10	0.737
NC_013939_3	3.17\|527235\|36\|NC_013939\|CRISPRCasFinder,CRT,PILER-CR	527235-527270	36	MN693520	Marine virus AFVG_25M327, complete genome	46874-46909	10	0.722
NC_013939_3	3.1\|526159\|37\|NC_013939\|CRISPRCasFinder,CRT	526159-526195	37	MN694287	Marine virus AFVG_250M724, complete genome	34179-34215	11	0.703

1. spacer 2.12|515499|37|NC_013939|CRISPRCasFinder,CRT matches to NZ_CP053952 (Bacillus cereus strain FDAARGOS_798 plasmid unnamed1, complete sequence) position: , mismatch: 10, identity: 0.73

ctcactgtgttttagaaattagaagcttaaaaaatgg	CRISPR spacer
ttcgatatgttttaaaaattagaagctcaaaaatgtt	Protospacer
.**. *.*******.************.*****

2. spacer 2.12|515499|37|NC_013939|CRISPRCasFinder,CRT matches to NZ_CP053949 (Bacillus cereus strain FDAARGOS_799 plasmid unnamed1, complete sequence) position: , mismatch: 10, identity: 0.73

ctcactgtgttttagaaattagaagcttaaaaaatgg	CRISPR spacer
ttcgatatgttttaaaaattagaagctcaaaaatgtt	Protospacer
.**. *.*******.************.*****

3. spacer 2.41|515501|37|NC_013939|PILER-CR matches to NZ_CP053952 (Bacillus cereus strain FDAARGOS_798 plasmid unnamed1, complete sequence) position: , mismatch: 10, identity: 0.73

ctcactgtgttttagaaattagaagcttaaaaaatgg	CRISPR spacer
ttcgatatgttttaaaaattagaagctcaaaaatgtt	Protospacer
.**. *.*******.************.*****

4. spacer 2.41|515501|37|NC_013939|PILER-CR matches to NZ_CP053949 (Bacillus cereus strain FDAARGOS_799 plasmid unnamed1, complete sequence) position: , mismatch: 10, identity: 0.73

ctcactgtgttttagaaattagaagcttaaaaaatgg	CRISPR spacer
ttcgatatgttttaaaaattagaagctcaaaaatgtt	Protospacer
.**. *.*******.************.*****

5. spacer 3.9|526692|38|NC_013939|CRISPRCasFinder,CRT,PILER-CR matches to EU409559 (Lactobacillus phage JCL1032, complete genome) position: , mismatch: 10, identity: 0.737

gaaaaattaggaaaagcacgctaaaaagcgtgcttttt	CRISPR spacer
aggccactaaaaaaagcacgttcaaaagcgtgcttttt	Protospacer
...  *.**..*********.* ***************

6. spacer 3.17|527235|36|NC_013939|CRISPRCasFinder,CRT,PILER-CR matches to MN693520 (Marine virus AFVG_25M327, complete genome) position: , mismatch: 10, identity: 0.722

aaggggctcaaagcgtggaataataaaagagttttc	CRISPR spacer
aaaaaagagtaagggtggaataataaaaaagttttc	Protospacer
**....    *** **************.*******

7. spacer 3.1|526159|37|NC_013939|CRISPRCasFinder,CRT matches to MN694287 (Marine virus AFVG_250M724, complete genome) position: , mismatch: 11, identity: 0.703

aaagaacttgagaaggaagtttatattgatctacctt	CRISPR spacer
ttagaacttcagaaggaagtttataatggcattaaat	Protospacer
  ******* *************** **.. *    *

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

159279 : 172832

Bacillus_phage(25.0%)

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_013006915.1\|159279_159975_+	ribonuclease III	H8ZJC7	Ostreococcus_tauri_virus	5.0e-25	34.4
WP_013006916.1\|159975_160986_+	radical SAM protein	NA	NA	NA	NA
WP_013006917.1\|160909_161440_+	16S rRNA (guanine(966)-N(2))-methyltransferase RsmD	NA	NA	NA	NA
WP_041223525.1\|161433_161925_+	pantetheine-phosphate adenylyltransferase	A0A1B1IVQ3	uncultured_Mediterranean_phage	2.8e-30	50.7
WP_013006919.1\|161905_162928_+	deoxyguanosinetriphosphate triphosphohydrolase	NA	NA	NA	NA
WP_041223526.1\|162945_164142_+	response regulator	W8CYM9	Bacillus_phage	9.6e-08	29.1
WP_013006921.1\|164155_164515_+	response regulator	W8CYM9	Bacillus_phage	3.8e-16	39.3
WP_013006922.1\|164511_164979_+	chemotaxis protein CheW	NA	NA	NA	NA
WP_013006923.1\|164989_167137_+	HAMP domain-containing protein	A0A2H4J162	uncultured_Caudovirales_phage	2.9e-15	49.5
WP_013006924.1\|167142_169470_+	response regulator	Q56AR1	Bacillus_thuringiensis_phage	1.9e-12	25.3
WP_013006925.1\|169450_169819_+	hypothetical protein	NA	NA	NA	NA
WP_013006926.1\|169796_171191_+	response regulator	NA	NA	NA	NA
WP_013006927.1\|171177_172224_+	phosphoribosylformylglycinamidine cyclo-ligase	Q58MH8	Prochlorococcus_phage	5.0e-61	42.6
WP_013006928.1\|172220_172832_+	phosphoribosylglycinamide formyltransferase	M4QRX9	Synechococcus_phage	1.1e-28	40.1

DBSCAN-SWA_2

1192888 : 1200924

Tetraselmis_virus(16.67%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_013007905.1\|1192888_1193386_+	5-(carboxyamino)imidazole ribonucleotide mutase	A0A2P0VNU7	Tetraselmis_virus	7.5e-23	44.1
WP_013007906.1\|1193386_1193998_+	threonylcarbamoyl-AMP synthase	NA	NA	NA	NA
WP_013007907.1\|1194059_1194335_+	integration host factor subunit alpha	A0A0H3UZA0	Geobacillus_virus	1.0e-13	41.6
WP_013007908.1\|1194327_1194642_+	MerR family transcriptional regulator	NA	NA	NA	NA
WP_041223650.1\|1194770_1195010_-	hypothetical protein	NA	NA	NA	NA
WP_013007909.1\|1195112_1195892_+	ParA family protein	E9LUK9	Lactobacillus_phage	6.7e-10	24.6
WP_013007910.1\|1195894_1197403_+	Hsp70 family protein	F2Y2E1	Organic_Lake_phycodnavirus	5.6e-61	30.8
WP_013007911.1\|1197445_1199386_+	methyl-accepting chemotaxis protein	A0A2H4J162	uncultured_Caudovirales_phage	6.8e-11	60.9
WP_013007912.1\|1199418_1200924_+	chemotaxis protein CheW	A0A248SKJ8	Salicola_phage	2.3e-06	29.1

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

2. NC_013940

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Crispr_ID: NC_013940_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_013940_1

77878-78375

TypeI-B

Consensus_repeat	Method
GTTTCAACTCCTGATAGGTACAATATAAAC	CRISPRCasFinder
GTTTCAACTCCTGATAGGTACAATATAAAC	CRT
GTTTCAACTCCTGATAGGTACAATATAAAC	PILER-CR

7 spacers

cas3,cas5,cas7,cas8b1,cas6

The CRISPR arrays of NC_013940_1

>merge|NC_013940|1|77878-78375|CRISPRCasFinder,CRT,PILER-CR
AAATTAATTCCTAATAGGTACAATACAAACAGAACACCTAAAATAATTACCACAACTATAACTTCTGTGTTTCAACTCCTAATAGGTACAATATAAACAAAAATCACCATTACATCATTTATTGCTTTTGTAATGTTTCAACTCCTGATAGGTACAATATAAACACTGATTATTTTGAGATATGGTGGGATGCAGATAAATTGTTTCAACTCCTGATAGGTACAATATAAACAAAGTTTAATAAAAAGGAAAGATGTGTCGGATATAAGTTTCAACTCCTGATAGGTACAATATAAACTGAAATGATGTATTTGATGAAAGTGATACAACGTGGTTTCAACTCCTGATAGGTACAATATAAACGTGCTTAGTAATACTAATACACAAATATTTTTGAAAACGTTTCAACTCCTGATAGGTACAATATAAACAGCTCAACAAAAATAGCATAACTACTAGCTGTAAGCGGTTTCAACTCCTGATAGGTACAATATAAAC

>NC_013940|1|1|77878-78375|CRISPRCasFinder
AAATTAATTCCTAATAGGTACAATACAAAC	AGAACACCTAAAATAATTACCACAACTATAACTTCTGT
GTTTCAACTCCTAATAGGTACAATATAAAC	AAAAATCACCATTACATCATTTATTGCTTTTGTAAT
GTTTCAACTCCTGATAGGTACAATATAAAC	ACTGATTATTTTGAGATATGGTGGGATGCAGATAAATT
GTTTCAACTCCTGATAGGTACAATATAAAC	AAAGTTTAATAAAAAGGAAAGATGTGTCGGATATAA
GTTTCAACTCCTGATAGGTACAATATAAAC	TGAAATGATGTATTTGATGAAAGTGATACAACGTG
GTTTCAACTCCTGATAGGTACAATATAAAC	GTGCTTAGTAATACTAATACACAAATATTTTTGAAAAC
GTTTCAACTCCTGATAGGTACAATATAAAC	AGCTCAACAAAAATAGCATAACTACTAGCTGTAAGCG
GTTTCAACTCCTGATAGGTACAATATAAAC

>NC_013940|1|1|77878-78375|CRT
AAATTAATTCCTAATAGGTACAATACAAAC	AGAACACCTAAAATAATTACCACAACTATAACTTCTGT
GTTTCAACTCCTAATAGGTACAATATAAAC	AAAAATCACCATTACATCATTTATTGCTTTTGTAAT
GTTTCAACTCCTGATAGGTACAATATAAAC	ACTGATTATTTTGAGATATGGTGGGATGCAGATAAATT
GTTTCAACTCCTGATAGGTACAATATAAAC	AAAGTTTAATAAAAAGGAAAGATGTGTCGGATATAA
GTTTCAACTCCTGATAGGTACAATATAAAC	TGAAATGATGTATTTGATGAAAGTGATACAACGTG
GTTTCAACTCCTGATAGGTACAATATAAAC	GTGCTTAGTAATACTAATACACAAATATTTTTGAAAAC
GTTTCAACTCCTGATAGGTACAATATAAAC	AGCTCAACAAAAATAGCATAACTACTAGCTGTAAGCG
GTTTCAACTCCTGATAGGTACAATATAAAC

>NC_013940|1|1|77946-78375|PILER-CR
GTTTCAACTCCTAATAGGTACAATATAAAC	AAAAATCACCATTACATCATTTATTGCTTTTGTAAT
GTTTCAACTCCTGATAGGTACAATATAAAC	ACTGATTATTTTGAGATATGGTGGGATGCAGATAAATT
GTTTCAACTCCTGATAGGTACAATATAAAC	AAAGTTTAATAAAAAGGAAAGATGTGTCGGATATAA
GTTTCAACTCCTGATAGGTACAATATAAAC	TGAAATGATGTATTTGATGAAAGTGATACAACGTG
GTTTCAACTCCTGATAGGTACAATATAAAC	GTGCTTAGTAATACTAATACACAAATATTTTTGAAAAC
GTTTCAACTCCTGATAGGTACAATATAAAC	AGCTCAACAAAAATAGCATAACTACTAGCTGTAAGCG
GTTTCAACTCCTGATAGGTACAATATAAAC

Protein	Signature genes	Signature genes Name	Protein_function
NC_013940.1\|WP_013008926.1\|75652_75883_-\|hypothetical-protein	unknown	unknown	unknown
NC_013940.1\|WP_013008925.1\|75257_75596_-\|hypothetical-protein	unknown	unknown	unknown
NC_013940.1\|WP_013008930.1\|81034_81730_-\|type-I-B-CRISPR-associated-protein-Cas5	cas5	cls001430_cas5_CAS-I-B	gnl\|CDD\|131641
NC_013940.1\|WP_013008928.1\|77148_77820_+\|hypothetical-protein	unknown	unknown	unknown
NC_013940.1\|WP_013008921.1\|70107_70680_-\|dUTP-diphosphatase	unknown	unknown	gnl\|CDD\|234802
NC_013940.1\|WP_013008932.1\|82682_84569_-\|TIGR02556-family-CRISPR-associated-protein	cas8b1	cd09672_cas8b1_CAS-I-B	gnl\|CDD\|378190
NC_013940.1\|WP_161595894.1\|68432_69278_+\|Flp-pilus-assembly-complex-ATPase-component-TadA	unknown	unknown	gnl\|CDD\|273613
NC_013940.1\|WP_013008922.1\|71056_71929_+\|DsbA-family-protein	unknown	unknown	gnl\|CDD\|224565
NC_013940.1\|WP_013008929.1\|78607_81013_-\|CRISPR-associated-helicase/endonuclease-Cas3	cas3	COG1203_cas3_CAS-I	gnl\|CDD\|224124
NC_013940.1\|WP_013008936.1\|88195_88540_+\|hypothetical-protein	unknown	unknown	unknown
NC_013940.1\|WP_013008923.1\|72100_73600_+\|PhoH-family-protein	unknown	unknown	gnl\|CDD\|224787
NC_013940.1\|WP_013008933.1\|84608_85379_-\|CRISPR-associated-endoribonuclease-Cas6	cas6	COG1583_cas6_CAS-I:CAS-III:CAS-IV	gnl\|CDD\|187889
NC_013940.1\|WP_013008931.1\|81742_82651_-\|type-I-B-CRISPR-associated-protein-Cas7/Csh2	cas7	cd09690_cas7_CAS-I-B	gnl\|CDD\|274217
NC_013940.1\|WP_013008927.1\|76161_77127_+\|tyrosine-type-recombinase/integrase	unknown	unknown	gnl\|CDD\|227308
NC_013940.1\|WP_013008938.1\|88956_89433_+\|hypothetical-protein	unknown	unknown	unknown
NC_013940.1\|WP_013008937.1\|88577_88898_+\|hypothetical-protein	unknown	unknown	unknown
NC_013940.1\|WP_013008920.1\|69274_69844_-\|hypothetical-protein	unknown	unknown	unknown
NC_013940.1\|WP_013008935.1\|87747_88086_+\|hypothetical-protein	unknown	unknown	unknown
NC_013940.1\|WP_013008924.1\|73658_75251_+\|bacteriohemerythrin	unknown	unknown	gnl\|CDD\|214599
NC_013940.1\|WP_153801540.1\|86846_87746_+\|nucleotidyl-transferase-AbiEii/AbiGii-toxin-family-protein	unknown	unknown	unknown

Protein	Function_ID	Function_description	E-value
NC_013940.1\|WP_013008923.1\|72100_73600_+\|PhoH-family-protein	gnl\|CDD\|224787	COG1875, COG1875, NYN ribonuclease and ATPase of PhoH family domains [General function prediction only].	2.66375e-116
NC_013940.1\|WP_013008933.1\|84608_85379_-\|CRISPR-associated-endoribonuclease-Cas6	gnl\|CDD\|187889	cd09759, Cas6_I-A, CRISPR/Cas system-associated RAMP superfamily protein Cas6. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas6 is an endoribonuclease that generates crRNAs, predicted subunit of Cascade complex; RAMP superfamily protein; Possesses double RRM/ferredoxin fold.	9.03796e-35
NC_013940.1\|WP_013008931.1\|81742_82651_-\|type-I-B-CRISPR-associated-protein-Cas7/Csh2	gnl\|CDD\|274217	TIGR02590, hypothetical_protein_MM_0563, CRISPR-associated protein Cas7/Csh2, subtype I-B/HMARI. This model represents one of two closely related CRISPR-associated proteins that belong to the larger family of TIGR01595. Members are the Csh2 protein of the Hmari subtype of CRISPR/cas system. CRISPR stands for Clustered Regularly Interspaced Short Palindromic Repeats. The related model is TIGR02589, the Csd3 protein of the Dvulg CRISPR subtype.	4.33948e-90
NC_013940.1\|WP_013008927.1\|76161_77127_+\|tyrosine-type-recombinase/integrase	gnl\|CDD\|227308	COG4974, XerD, Site-specific recombinase XerD [DNA replication, recombination, and repair].	6.15439e-31
NC_013940.1\|WP_013008930.1\|81034_81730_-\|type-I-B-CRISPR-associated-protein-Cas5	gnl\|CDD\|131641	TIGR02592, hypothetical_protein_CTC_01466, CRISPR-associated protein Cas5, subtype I-B/HMARI. This is a CRISPR-associated protein unique to the hmari subtype of cas genes and CRISPR repeat, which is the only subtype present in Haloarcula marismortui ATCC 43049. The hmari type, though uncommon, is also found in the Aquificae, Thermotogae, Firmicutes, and Dictyoglomi.	3.46809e-29
NC_013940.1\|WP_013008921.1\|70107_70680_-\|dUTP-diphosphatase	gnl\|CDD\|234802	PRK00601, dut, dUTP diphosphatase.	7.17715e-71
NC_013940.1\|WP_013008932.1\|82682_84569_-\|TIGR02556-family-CRISPR-associated-protein	gnl\|CDD\|378190	pfam09484, Cas_TM1802, CRISPR-associated protein TM1802 (cas_TM1802). Clusters of short DNA repeats with non-homologous spacers, which are found at regular intervals in the genomes of phylogenetically distinct prokaryotic species, comprise a family with recognisable features. This family is known as CRISPR (short for Clustered, Regularly Interspaced Short Palindromic Repeats). A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins. This minor cas protein is found in at least five prokaryotic genomes: Methanosarcina mazei, Sulfurihydrogenibium azorense, Thermotoga maritima, Carboxydothermus hydrogenoformans, and Dictyoglomus thermophilum, the first of which is archaeal while the rest are bacterial.	1.27844e-84
NC_013940.1\|WP_161595894.1\|68432_69278_+\|Flp-pilus-assembly-complex-ATPase-component-TadA	gnl\|CDD\|273613	TIGR01420, pilT_fam, pilus retraction protein PilT. This model represents the PilT subfamily of proteins related to GspE, a protein involved in type II secretion (also called the General Secretion Pathway). PilT is an apparent cytosolic ATPase associated with type IV pilus systems. It is not required for pilin biogenesis, but is required for twitching motility and social gliding behaviors, shown in some species, powered by pilus retraction. Members of this family may be found in some species that type IV pili but have related structures for DNA uptake and natural transformation. [Cell envelope, Surface structures, Cellular processes, Chemotaxis and motility].	2.51373e-74
NC_013940.1\|WP_013008922.1\|71056_71929_+\|DsbA-family-protein	gnl\|CDD\|224565	COG1651, DsbG, Protein-disulfide isomerase [Posttranslational modification, protein turnover, chaperones].	6.68255e-17
NC_013940.1\|WP_013008929.1\|78607_81013_-\|CRISPR-associated-helicase/endonuclease-Cas3	gnl\|CDD\|224124	COG1203, COG1203, CRISPR-associated helicase Cas3 [Defense mechanisms].	2.052e-48
NC_013940.1\|WP_013008924.1\|73658_75251_+\|bacteriohemerythrin	gnl\|CDD\|214599	smart00283, MA, Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). Thought to undergo reversible methylation in response to attractants or repellants during bacterial chemotaxis.	2.79392e-55

>NC_013940.1|WP_013008928.1|77148_77820_+|hypothetical-protein
MKNINSDITQQDIIDNFQNLYANFLQKIDNLIQDNLDNITSNTINHLYYLQFNLLKNFKGNSSGFTGLSEFLIVRFIIHYITKKYNQNFKLLPITKDIKYWQSQNFKINVQQTIKLPKPVKVGNKKQNKIQPDIIIKKENKIISYIEIKIYLKDFKILEDLIKKYEVLLENNKNNYKLLFILFNGNDNIMEKLDKYKLQNTWFNYIVLNKSNKKFIDAVNKIV
>NC_013940.1|WP_013008927.1|76161_77127_+|tyrosine-type-recombinase/integrase
MELEPLIKDNLVNDLIRWKKLFIEDLRVRNYSNNTIELYSKEIDYFIEYSRGYVDEMDINDINRPYIQGSLAYREEISIKDSISSNTKQIYIKALKQFFIFITENNREYKDYTTIFRKIKIVTQTKEKEYLTEQEISKLLNYLEVLKSRRESIVTFRNVFLIKLLLYSGLRISEALQLKFTDFEEIAINNTYYYQIKVKGKGQTESYAYVPKELIEDEYLYLSESYSNKHNNIFITRNGSILKRQDAYKIITNIYKKAGINKTGIHLLRHTFAMKLVNAGVDLLHIKELLRHKNVNSTLVYAKSTQQMVDESFKKSILNKD
>NC_013940.1|WP_013008926.1|75652_75883_-|hypothetical-protein
MSELKNNITNKNNTTEFVNKRIDLTKKSLKQIKIIASILDDNVDNKFDKNTISYIINKAVNHYFNSEEIQNQLKEL
>NC_013940.1|WP_013008925.1|75257_75596_-|hypothetical-protein
MLNTDKELITILELTKIETLPPKDDDRLIILSQEVTKMIYSYLNIQKITEFELWNTYFSKYMKYENFLSCLQNSQGKYKYIKYILSFYRYITNKTYNLSTNSSLINNHSIIT
>NC_013940.1|WP_013008924.1|73658_75251_+|bacteriohemerythrin
MKINLKIKISLGILFVGILGGIIGLFNIYGISNNISLSLLIKLDLFLMFLGTVSAVAIIIYLNSYIFKNLNVLKRNIANISQGILEFENMNNKSKDELSETVSNMYKSCIKISDILKEFFKTSLELKSASEDLANASDEAHKNLTELNDEVQSISTAAEELNSTSKNIYDNSVEIVESITNSESKLNDSINIISENKEQVEKVAETSSLVVEKVTEFRKLSEEISRIVSTINEIADQTNLLALNAAIEAARAGEHGRGFAVVADEVRKLANKTTDSTKLIEEAIKSIQQEADDISNVVMKEQEEVKNSVTKVNESIESINLVKESFNDVKLRVESITNAINEESLAIEDITRNITNVSYKLNEIKNIVDKTQQSSGELLEISVQLMENISFFKIDYKGKFIEWSDKLSVGIDKFDEQHKNLVRLVNEIYDAVNADKSAVVLEKILNELVEYTVYHFNSEEEAFKRFEYPEYEKHREIHEDLKEQVGEFLERYKKGDTAIGFNLLNFLKKWLVNHIMGEDKKYGAFLKGKI
>NC_013940.1|WP_013008923.1|72100_73600_+|PhoH-family-protein
MQAKLYVLDTNILLYDPDSLNGFEEHVVCIPSVVLEELDKFKKDNNIRGLNARKVIRKLDTWINKEHYNIIIKNTNFDIHIISTRNDLNSIVFIINFITKTKEGAKTLLLDENKNDDKIIIDVQNIEKYKEKIFNVLSDKYNFDLKIKNMIFVSKDLHLRIKAKLFDILTEDYRKHKLVKLPSFNGLYLTVPSEIINQIYSKGEYFFEETHGKYIFENNYTGYSLKKFLEETGFSSNYENIDADTTINYNDYFLIRSNENEKHSVLVRFVGDKLLKVENINEVFGIYPKNHKQKFFIDALLNDTIDVVFGIGVAGSGKTLLSIAAGLYLTLEQKKYNKIIVTRPVIPFGRDIGFLPGSAEEKVHPYMLPIFDNIDFIFKDEEKVNVTSKDYLMQSDLISIMPLPFIRGRSFNNSFIIVDEAQNLTPLEVKTILTRVGENSKIVLTGDIFQIDVPYIDERDNGLIVAAESFRENNIKNSAVIFFDHCERSIVADIASQIL
>NC_013940.1|WP_013008922.1|71056_71929_+|DsbA-family-protein
MKKNILKIINFVMLLLFVLTSISMASGNSYSNTISQKLKKIIESKDNNIEVTVEKSIPSKEIAGFAYVLLKIHPKGNKELSQELFVLSNGKYIIPALIDIDKDLNMLDLVKIDINKIQFNPDKNKLELGNADAKVKIVMFSDFECPFCRQAFPFIKNLAQKYNKQVAVYHYNFPLNFHKHARNLAIVYEAGKELGLNLADVLYSMKLDNIKSIDDILNNLKDKIPAPKYGKLKDLVKKSNKYNKIIESDMKVGSDLGVKGTPFFIINGSIISGFNPNLIKIAVDKYVKSK
>NC_013940.1|WP_013008921.1|70107_70680_-|dUTP-diphosphatase
MKIPYYYCVNCAQAEILTNHKVYCKLKSQVNTYDVGINYQKVTECPVYNVRIKKIHPDAQIPQYATNGSSGFDFYTVEEIVIQPKETKLIKTGLQIALPIGYELQIRPRSGLSLKTPLRVANTPGTVDADYRGEICILVWNTEDKPITIEKGTRIAQGVICKIEQVNFIETDELDDTDRGDGGFGSTGVK
>NC_013940.1|WP_013008920.1|69274_69844_-|hypothetical-protein
MLLKYYKKVEKNLEKQYEEKYEEISTKLEKSLSLENELKGKIININRKIDELKSQLQKYRSEYDAVSNQVEYYEKQLKLMDTKLYYILMLIKKYVETNKITTIKTNYHHNKIWIMLYANLNNNKIDIYFISIEQKKDGLYNVIRLNNLNKKSSSKVFNDTQLIDYLEKIIKHHKTIIKNNILNIINKID
>NC_013940.1|WP_161595894.1|68432_69278_+|Flp-pilus-assembly-complex-ATPase-component-TadA
MELANNYISSYEHEIKSEIKLKNYLKRISSLNFSFGLDNYRFRGNLFVASNIIHCVLRIISSDIKSFEELGFNRTQMISLLNSKSHGLILISGVTGSGKSTTAASILDYYNKTRKYHIITIEDPVEYKLVEKQSKITQREVGSDTVNFKQALKDSLRQKPHVLFIGEVRDLEVAEILLHATLTGHLVITTIHASSVIQSINRFIGLFPASQEEVIKRTFAHVLLGCINQRLEYVPTSNKMQLKYEMLIVDDTARVIIQQDKRMYGQLKDVMRRQGSPILEY
>NC_013940.1|WP_013008929.1|78607_81013_-|CRISPR-associated-helicase/endonuclease-Cas3
MATKSGLLSHPDKQLEDHISNVIKLVNNFYDNTKLNDNILKNILTIISFAHDVGKATTAFQEYIKGNSELKNKPETTHSLFGACISLYLTDRYLKSINQNNDFLLFLSFVIPRLHHSNLVDVYQITLLDENQIELLTTQLNLLKINQDQFYQFIENTKINNKDLIKFNLNEINFNNIILLIRQINKFIKNIRTTVNGLNKTNILLKSRINSKPINIDYYIIVSLLYSILIDADKSDAGIKADKNILFKRDNLSSEIIDNFINTLKFKKTDIVKLRQQAFQEITTKDIDINNKIYTLTLPTGLGKTLLSFKLALKLSNKIKEEKNVIPKIIYCLPFLSVIEQNYNVIKSVLETNNIKVDNSILIKHHYLTDMTYTYQNDEFEYDTSKLLIEGWNGQIITTTFLQFFYSLIGNKNKMLRKFHKLTNSIVILDEIQSIPQKYWLLLKEVLNKMAEKFNFYVILTTATQPMIFDKKQYIELASNNYFDKLDRYVVNINKDLKTVDEFYYSLNIEKNKTYLFIMNTVNSAKRLYELLKKEYKNDILFLSTHITPKERLKRIQQIKNNDKRIVVSTQLVEAGVDIDFDVVYRDFAPLDSLIQSAGRCNRNGEKTTGIFNILKLYNENHQGRLYGSYIYDTLLLTATEQILDKEFFTEPEFIQLTNKYFQKVNEIKSNSDSLELLKILSELKFTYEKDNNKITSVEDFKLINNNYPRIDVFIQLDDTAVTIWKEYIKISNIKDYLERKRLFNNIKKDFFEYIISVPIKDNMNIPPIENNFYYVPIDNLDDYYDYETGFKTDSNLYIAL
>NC_013940.1|WP_013008930.1|81034_81730_-|type-I-B-CRISPR-associated-protein-Cas5
MKVLVFDIWGDYAHYRKFYTTSSPLTFSCPTPTAVYGMLGAILGTKGYKHLEIFNYSTTKLGIQILKPITKVRMSTNYVLAKEINDLWYLKDRTPIQVEYLKNPSFRLFIHINNNEIFTNLINKIQNKLLYYTVSLGTANLIANYKYIGVFKAEHINHTDTIKTIIPLENIENIKAVSGKKYFKETLPVDMSTDRQVKLYKEILMELNGAALEGEFKECYKLDNGDIISFI
>NC_013940.1|WP_013008931.1|81742_82651_-|type-I-B-CRISPR-associated-protein-Cas7/Csh2
MSENIVKNRREYLFLYDVKYANPNGDPNDENRPRIDEETQINIVTDVRLKRTIRDYLLNYENKEIFIREIFNKNGKLQEAKDRAANFGKNPEKILAECIDIRLFGATIPLEKKSNSGKSITFTGPIQFNIGQSLHKVKLMHIKGTGAFASGENKEQKTFREDWVLPYSLIAFHAILNEQAAVDTKLTDEDVEYFKKAMWEGTKNLITRSKTEQLPRLLIEVIFKEGVCTHIGELHKYVKIESELEDEEIRSTEDFVLNVDELIDVLEEYADKIEKVTFKVDRKLKLNKPLASDEVKFEKIEF
>NC_013940.1|WP_013008932.1|82682_84569_-|TIGR02556-family-CRISPR-associated-protein
MITALKDLGELVYNDYITGLYDSKILSSKISIAELCDIKSLSDIKSLSDEKINIFTDTLTDDLSNDSYIIREWCLEFDNNYELISPNIIEKDFQKENSYLYLYKRGSSRGTNYSPAFLDKNANTKLNKLEQWFKNHLHINEIAQMFNEVEKHKNTILNDLIKLTQIINPKKSSREKAIFTIKINGKYLFEIDKPNFKRILVEDYILKVTNNFQKTFSTCSICRTHKQVFSTSEIFRFYTTDKVVYVAGGFDKDKAWKNFPICLECFIKAIIGRKTVENNFKYSFYGSNYILIPKIILNKDNTILDEINNLLAVDKKQQNISNENRKYITNNKSEILDIISTYKDAISFYFLFLKKDNSAERIVLLVEDVYPSRLKTIFNAKEKIDKLFNIDYNLSYIYEFVKNDNKLFFDITNKIFKGGHLDFNLFIRLQMDGIREKLFKDNSRNKNKLKKTILSAIMNVRFLEELEILNKEVKPMQENSKFNEIFEKIGKKLNTPARRGIFLLGALVEKLIEIQKGKRTNSPFIKQLKGGKLTEKDIQSLFTNTLVKYREYDAYYPFVRILAKEISNYLLKENKFHMTVDEINYYLFAGTSYYNDVIEIAKQIAEEQKQIQNNNNENNTEENTNKNE
>NC_013940.1|WP_013008933.1|84608_85379_-|CRISPR-associated-endoribonuclease-Cas6
MRMKIEINSNKNFILLPINHKHIIQGFLYNNLPKPLSDFLHNIGFFYYKRQFKLFTFSNLYSSYFQIITIQDNKKTDKYIKFKTPVTLYIASGINNFINNWNNNFLLSDNLKLGDNTVYIESIEVLPQPEITNKCLINTLSPITVYRTLENKKYHYYNPNDIDFNVLVKNNIKKKYALLTNTIINDFDFNMKNIKYKKIITKYIKKPKINKDFIIEAYDGIFEIETEPEILKTIYDVGLGAKNSQGFGMFSIIKNN
>NC_013940.1|WP_153801540.1|86846_87746_+|nucleotidyl-transferase-AbiEii/AbiGii-toxin-family-protein
MKRNAKSKSRGKNMEYKKFSNNITSTNITDDNFDWEHLLNVACKFHKIFPDGILIGGSVASIYAMHRVSFDIDFVFNDLKEKFEKFIDILEKGEIEVDNVKEEWEWELARMAKGKVILGNFDGVETGLRQLMRTKPLETTLYEVKPGKFIKIPTIEETLRTKAWMILSRNATRDYLDFCALAKQLYSEDPARLIKAMESFDDYYIDMYDKLKKRKPENKKSPLLQLLKQLAEPKPFDLNKIDLKKYKGIVKPWTEWKNIKKISQDAAVVLTEALTGIEPTFKKEIETKVKRDNDNLMEL
>NC_013940.1|WP_013008935.1|87747_88086_+|hypothetical-protein
MSNKNYENTKFTYRNIDKIDDMPETIEEVVSIFERGNDNQIIKLLALCQKEPFSEIANLVLDVCDYMEDNPEHAVYGLPTLFKKTILYYRNESKLESDLDKPFDNSLDDLNI
>NC_013940.1|WP_013008936.1|88195_88540_+|hypothetical-protein
MRKLFLVLTSFIILAMVIGCSGSSITMDDLKMLYPFFRDTKLQCSLDGNEVKCFDKRDKSNVVFYLNEKNIITKVVLKLKKGADVTITEKGKILKLIDEANSDYYRRKNTRRLF
>NC_013940.1|WP_013008937.1|88577_88898_+|hypothetical-protein
MSHVPEKNNVKMDYPLLFSAAEFLIGLTGAFGAIFVIMSLIPAIRYGLNFYALLSAILSLLGIILGMGIGFAFMRMVAASIDTRNYLYDIYLELKNLDKKTETKQE
>NC_013940.1|WP_013008938.1|88956_89433_+|hypothetical-protein
MKKLLVIFGLTTFLLVNNLFSVSYATENKTKTSEKPYYIIFDKNFIEHSLKGLTGCKILKVGKGDVSSYGITDFEYMSSTVDRKKGLPVKLYKFITNSLEIEKKYVQKRGYNALIVQDVEYVYGFDTNDSMSIINGKVGSRSLAVAVVYVDALIKCRN

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Crispr_ID: NC_013940_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_013940_2

85558-86387

TypeI-B

Consensus_repeat	Method
GTTTCAACTCCTGATAGGTACAATATAAAC	CRISPRCasFinder
GTTTCAACTCCTGATAGGTACAATATAAAC	CRT
GTTTCAACTCCTGATAGGTACAATATAAAC	PILER-CR

12 spacers

cas6,cas8b1,cas7,cas5,cas3

The CRISPR arrays of NC_013940_2

>merge|NC_013940|2|85558-86387|CRISPRCasFinder,CRT,PILER-CR
ACCTTATCTCCTAATAGATACAATACAAACAGAACACCTAAAATAATTACCACAACTATAACTTCTGTGTTTCAACTCCTGATAGGTACAATATAAACAAATATGGTAAACTAAAAGTTGATGATTACGTATATAGTTTCAACTCCTGATAGGTACAATATAAACGATATTCTTTGCAGTATACACCTTTATATTTAAACCGTTTCAACTCCTGATAGGTACAATATAAACTTGATAAATCAGTTGGACCAGAAATTAATTTCATTAGGTTTCAACTCCTGATAGGTACAATATAAACCTCATCCAATTCCTAAGTGTGAATTTGCTAACCTTGTTTCAACTCCTGATAGGTACAATATAAACTAGAAACAAATTTTTTGGAGCATGCTGCAAGAGGTGTGTTTCAACTCCTGATAGGTACAATATAAACTTGCACAAGCATATCCTTGCGCATGTACCAAGCCTCTTTGTTTCAACTCCTGATAGGTACAATATAAACTGCTTTTGCTGTTGTTTTTGTTGCTGTTGTTTTAGTTTCAACTCCTGATAGGTACAATATAAACTAACTATTGATGATATATTCTGTTTTGTTGTGCCTGTGTTTCAACTCCTGATAGGTACAATATAAACTTATATTTTTGTATAAATTATATGTATATGCATATTGTTTCAACTCCTGATAGGTACAATATAAACGCTTCAGCAATTCCATACTTATCACTTATTTTTATTGGTTTCAACTCCTGATAGGTACAATATAAACTGTATTTTTCAAAGTTTTTATCTTTTGTAACAAATTCGTTTCAACTCCTGATAGGTACAATATAAAC

>NC_013940|2|2|85558-86387|CRISPRCasFinder
ACCTTATCTCCTAATAGATACAATACAAAC	AGAACACCTAAAATAATTACCACAACTATAACTTCTGT
GTTTCAACTCCTGATAGGTACAATATAAAC	AAATATGGTAAACTAAAAGTTGATGATTACGTATATA
GTTTCAACTCCTGATAGGTACAATATAAAC	GATATTCTTTGCAGTATACACCTTTATATTTAAACC
GTTTCAACTCCTGATAGGTACAATATAAAC	TTGATAAATCAGTTGGACCAGAAATTAATTTCATTAG
GTTTCAACTCCTGATAGGTACAATATAAAC	CTCATCCAATTCCTAAGTGTGAATTTGCTAACCTT
GTTTCAACTCCTGATAGGTACAATATAAAC	TAGAAACAAATTTTTTGGAGCATGCTGCAAGAGGTGT
GTTTCAACTCCTGATAGGTACAATATAAAC	TTGCACAAGCATATCCTTGCGCATGTACCAAGCCTCTTT
GTTTCAACTCCTGATAGGTACAATATAAAC	TGCTTTTGCTGTTGTTTTTGTTGCTGTTGTTTTA
GTTTCAACTCCTGATAGGTACAATATAAAC	TAACTATTGATGATATATTCTGTTTTGTTGTGCCTGT
GTTTCAACTCCTGATAGGTACAATATAAAC	TTATATTTTTGTATAAATTATATGTATATGCATATT
GTTTCAACTCCTGATAGGTACAATATAAAC	GCTTCAGCAATTCCATACTTATCACTTATTTTTATTG
GTTTCAACTCCTGATAGGTACAATATAAAC	TGTATTTTTCAAAGTTTTTATCTTTTGTAACAAATTC
GTTTCAACTCCTGATAGGTACAATATAAAC

>NC_013940|2|2|85558-86387|CRT
ACCTTATCTCCTAATAGATACAATACAAAC	AGAACACCTAAAATAATTACCACAACTATAACTTCTGT
GTTTCAACTCCTGATAGGTACAATATAAAC	AAATATGGTAAACTAAAAGTTGATGATTACGTATATA
GTTTCAACTCCTGATAGGTACAATATAAAC	GATATTCTTTGCAGTATACACCTTTATATTTAAACC
GTTTCAACTCCTGATAGGTACAATATAAAC	TTGATAAATCAGTTGGACCAGAAATTAATTTCATTAG
GTTTCAACTCCTGATAGGTACAATATAAAC	CTCATCCAATTCCTAAGTGTGAATTTGCTAACCTT
GTTTCAACTCCTGATAGGTACAATATAAAC	TAGAAACAAATTTTTTGGAGCATGCTGCAAGAGGTGT
GTTTCAACTCCTGATAGGTACAATATAAAC	TTGCACAAGCATATCCTTGCGCATGTACCAAGCCTCTTT
GTTTCAACTCCTGATAGGTACAATATAAAC	TGCTTTTGCTGTTGTTTTTGTTGCTGTTGTTTTA
GTTTCAACTCCTGATAGGTACAATATAAAC	TAACTATTGATGATATATTCTGTTTTGTTGTGCCTGT
GTTTCAACTCCTGATAGGTACAATATAAAC	TTATATTTTTGTATAAATTATATGTATATGCATATT
GTTTCAACTCCTGATAGGTACAATATAAAC	GCTTCAGCAATTCCATACTTATCACTTATTTTTATTG
GTTTCAACTCCTGATAGGTACAATATAAAC	TGTATTTTTCAAAGTTTTTATCTTTTGTAACAAATTC
GTTTCAACTCCTGATAGGTACAATATAAAC

>NC_013940|2|2|85626-86387|PILER-CR
GTTTCAACTCCTGATAGGTACAATATAAAC	AAATATGGTAAACTAAAAGTTGATGATTACGTATATA
GTTTCAACTCCTGATAGGTACAATATAAAC	GATATTCTTTGCAGTATACACCTTTATATTTAAACC
GTTTCAACTCCTGATAGGTACAATATAAAC	TTGATAAATCAGTTGGACCAGAAATTAATTTCATTAG
GTTTCAACTCCTGATAGGTACAATATAAAC	CTCATCCAATTCCTAAGTGTGAATTTGCTAACCTT
GTTTCAACTCCTGATAGGTACAATATAAAC	TAGAAACAAATTTTTTGGAGCATGCTGCAAGAGGTGT
GTTTCAACTCCTGATAGGTACAATATAAAC	TTGCACAAGCATATCCTTGCGCATGTACCAAGCCTCTTT
GTTTCAACTCCTGATAGGTACAATATAAAC	TGCTTTTGCTGTTGTTTTTGTTGCTGTTGTTTTA
GTTTCAACTCCTGATAGGTACAATATAAAC	TAACTATTGATGATATATTCTGTTTTGTTGTGCCTGT
GTTTCAACTCCTGATAGGTACAATATAAAC	TTATATTTTTGTATAAATTATATGTATATGCATATT
GTTTCAACTCCTGATAGGTACAATATAAAC	GCTTCAGCAATTCCATACTTATCACTTATTTTTATTG
GTTTCAACTCCTGATAGGTACAATATAAAC	TGTATTTTTCAAAGTTTTTATCTTTTGTAACAAATTC
GTTTCAACTCCTGATAGGTACAATATAAAC

Protein	Signature genes	Signature genes Name	Protein_function
NC_013940.1\|WP_013008926.1\|75652_75883_-\|hypothetical-protein	unknown	unknown	unknown
NC_013940.1\|WP_013008925.1\|75257_75596_-\|hypothetical-protein	unknown	unknown	unknown
NC_013940.1\|WP_013008930.1\|81034_81730_-\|type-I-B-CRISPR-associated-protein-Cas5	cas5	cls001430_cas5_CAS-I-B	gnl\|CDD\|131641
NC_013940.1\|WP_013008941.1\|91448_92045_-\|hypothetical-protein	unknown	unknown	unknown
NC_013940.1\|WP_013008928.1\|77148_77820_+\|hypothetical-protein	unknown	unknown	unknown
NC_013940.1\|WP_013008932.1\|82682_84569_-\|TIGR02556-family-CRISPR-associated-protein	cas8b1	cd09672_cas8b1_CAS-I-B	gnl\|CDD\|378190
NC_013940.1\|WP_013008933.1\|84608_85379_-\|CRISPR-associated-endoribonuclease-Cas6	cas6	COG1583_cas6_CAS-I:CAS-III:CAS-IV	gnl\|CDD\|187889
NC_013940.1\|WP_013008942.1\|92213_94121_+\|hypothetical-protein	unknown	unknown	unknown
NC_013940.1\|WP_013008937.1\|88577_88898_+\|hypothetical-protein	unknown	unknown	unknown
NC_013940.1\|WP_013008929.1\|78607_81013_-\|CRISPR-associated-helicase/endonuclease-Cas3	cas3	COG1203_cas3_CAS-I	gnl\|CDD\|224124
NC_013940.1\|WP_013008936.1\|88195_88540_+\|hypothetical-protein	unknown	unknown	unknown
NC_013940.1\|WP_013008940.1\|90358_91411_-\|hypothetical-protein	unknown	unknown	unknown
NC_013940.1\|WP_013008939.1\|89578_90187_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|237030
NC_013940.1\|WP_013008931.1\|81742_82651_-\|type-I-B-CRISPR-associated-protein-Cas7/Csh2	cas7	cd09690_cas7_CAS-I-B	gnl\|CDD\|274217
NC_013940.1\|WP_013008927.1\|76161_77127_+\|tyrosine-type-recombinase/integrase	unknown	unknown	gnl\|CDD\|227308
NC_013940.1\|WP_013008938.1\|88956_89433_+\|hypothetical-protein	unknown	unknown	unknown
NC_013940.1\|WP_013008935.1\|87747_88086_+\|hypothetical-protein	unknown	unknown	unknown
NC_013940.1\|WP_013008924.1\|73658_75251_+\|bacteriohemerythrin	unknown	unknown	gnl\|CDD\|214599
NC_013940.1\|WP_013008943.1\|94289_95093_+\|hypothetical-protein	unknown	unknown	unknown
NC_013940.1\|WP_153801540.1\|86846_87746_+\|nucleotidyl-transferase-AbiEii/AbiGii-toxin-family-protein	unknown	unknown	unknown

Protein	Function_ID	Function_description	E-value
NC_013940.1\|WP_013008927.1\|76161_77127_+\|tyrosine-type-recombinase/integrase	gnl\|CDD\|227308	COG4974, XerD, Site-specific recombinase XerD [DNA replication, recombination, and repair].	6.15439e-31
NC_013940.1\|WP_013008931.1\|81742_82651_-\|type-I-B-CRISPR-associated-protein-Cas7/Csh2	gnl\|CDD\|274217	TIGR02590, hypothetical_protein_MM_0563, CRISPR-associated protein Cas7/Csh2, subtype I-B/HMARI. This model represents one of two closely related CRISPR-associated proteins that belong to the larger family of TIGR01595. Members are the Csh2 protein of the Hmari subtype of CRISPR/cas system. CRISPR stands for Clustered Regularly Interspaced Short Palindromic Repeats. The related model is TIGR02589, the Csd3 protein of the Dvulg CRISPR subtype.	4.33948e-90
NC_013940.1\|WP_013008930.1\|81034_81730_-\|type-I-B-CRISPR-associated-protein-Cas5	gnl\|CDD\|131641	TIGR02592, hypothetical_protein_CTC_01466, CRISPR-associated protein Cas5, subtype I-B/HMARI. This is a CRISPR-associated protein unique to the hmari subtype of cas genes and CRISPR repeat, which is the only subtype present in Haloarcula marismortui ATCC 43049. The hmari type, though uncommon, is also found in the Aquificae, Thermotogae, Firmicutes, and Dictyoglomi.	3.46809e-29
NC_013940.1\|WP_013008932.1\|82682_84569_-\|TIGR02556-family-CRISPR-associated-protein	gnl\|CDD\|378190	pfam09484, Cas_TM1802, CRISPR-associated protein TM1802 (cas_TM1802). Clusters of short DNA repeats with non-homologous spacers, which are found at regular intervals in the genomes of phylogenetically distinct prokaryotic species, comprise a family with recognisable features. This family is known as CRISPR (short for Clustered, Regularly Interspaced Short Palindromic Repeats). A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins. This minor cas protein is found in at least five prokaryotic genomes: Methanosarcina mazei, Sulfurihydrogenibium azorense, Thermotoga maritima, Carboxydothermus hydrogenoformans, and Dictyoglomus thermophilum, the first of which is archaeal while the rest are bacterial.	1.27844e-84
NC_013940.1\|WP_013008933.1\|84608_85379_-\|CRISPR-associated-endoribonuclease-Cas6	gnl\|CDD\|187889	cd09759, Cas6_I-A, CRISPR/Cas system-associated RAMP superfamily protein Cas6. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas6 is an endoribonuclease that generates crRNAs, predicted subunit of Cascade complex; RAMP superfamily protein; Possesses double RRM/ferredoxin fold.	9.03796e-35
NC_013940.1\|WP_013008929.1\|78607_81013_-\|CRISPR-associated-helicase/endonuclease-Cas3	gnl\|CDD\|224124	COG1203, COG1203, CRISPR-associated helicase Cas3 [Defense mechanisms].	2.052e-48
NC_013940.1\|WP_013008924.1\|73658_75251_+\|bacteriohemerythrin	gnl\|CDD\|214599	smart00283, MA, Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). Thought to undergo reversible methylation in response to attractants or repellants during bacterial chemotaxis.	2.79392e-55
NC_013940.1\|WP_013008939.1\|89578_90187_+\|hypothetical-protein	gnl\|CDD\|237030	PRK12270, kgd, multifunctional oxoglutarate decarboxylase/oxoglutarate dehydrogenase thiamine pyrophosphate-binding subunit/dihydrolipoyllysine-residue succinyltransferase subunit.	0.000355696

>NC_013940.1|WP_013008933.1|84608_85379_-|CRISPR-associated-endoribonuclease-Cas6
MRMKIEINSNKNFILLPINHKHIIQGFLYNNLPKPLSDFLHNIGFFYYKRQFKLFTFSNLYSSYFQIITIQDNKKTDKYIKFKTPVTLYIASGINNFINNWNNNFLLSDNLKLGDNTVYIESIEVLPQPEITNKCLINTLSPITVYRTLENKKYHYYNPNDIDFNVLVKNNIKKKYALLTNTIINDFDFNMKNIKYKKIITKYIKKPKINKDFIIEAYDGIFEIETEPEILKTIYDVGLGAKNSQGFGMFSIIKNN
>NC_013940.1|WP_013008932.1|82682_84569_-|TIGR02556-family-CRISPR-associated-protein
MITALKDLGELVYNDYITGLYDSKILSSKISIAELCDIKSLSDIKSLSDEKINIFTDTLTDDLSNDSYIIREWCLEFDNNYELISPNIIEKDFQKENSYLYLYKRGSSRGTNYSPAFLDKNANTKLNKLEQWFKNHLHINEIAQMFNEVEKHKNTILNDLIKLTQIINPKKSSREKAIFTIKINGKYLFEIDKPNFKRILVEDYILKVTNNFQKTFSTCSICRTHKQVFSTSEIFRFYTTDKVVYVAGGFDKDKAWKNFPICLECFIKAIIGRKTVENNFKYSFYGSNYILIPKIILNKDNTILDEINNLLAVDKKQQNISNENRKYITNNKSEILDIISTYKDAISFYFLFLKKDNSAERIVLLVEDVYPSRLKTIFNAKEKIDKLFNIDYNLSYIYEFVKNDNKLFFDITNKIFKGGHLDFNLFIRLQMDGIREKLFKDNSRNKNKLKKTILSAIMNVRFLEELEILNKEVKPMQENSKFNEIFEKIGKKLNTPARRGIFLLGALVEKLIEIQKGKRTNSPFIKQLKGGKLTEKDIQSLFTNTLVKYREYDAYYPFVRILAKEISNYLLKENKFHMTVDEINYYLFAGTSYYNDVIEIAKQIAEEQKQIQNNNNENNTEENTNKNE
>NC_013940.1|WP_013008931.1|81742_82651_-|type-I-B-CRISPR-associated-protein-Cas7/Csh2
MSENIVKNRREYLFLYDVKYANPNGDPNDENRPRIDEETQINIVTDVRLKRTIRDYLLNYENKEIFIREIFNKNGKLQEAKDRAANFGKNPEKILAECIDIRLFGATIPLEKKSNSGKSITFTGPIQFNIGQSLHKVKLMHIKGTGAFASGENKEQKTFREDWVLPYSLIAFHAILNEQAAVDTKLTDEDVEYFKKAMWEGTKNLITRSKTEQLPRLLIEVIFKEGVCTHIGELHKYVKIESELEDEEIRSTEDFVLNVDELIDVLEEYADKIEKVTFKVDRKLKLNKPLASDEVKFEKIEF
>NC_013940.1|WP_013008930.1|81034_81730_-|type-I-B-CRISPR-associated-protein-Cas5
MKVLVFDIWGDYAHYRKFYTTSSPLTFSCPTPTAVYGMLGAILGTKGYKHLEIFNYSTTKLGIQILKPITKVRMSTNYVLAKEINDLWYLKDRTPIQVEYLKNPSFRLFIHINNNEIFTNLINKIQNKLLYYTVSLGTANLIANYKYIGVFKAEHINHTDTIKTIIPLENIENIKAVSGKKYFKETLPVDMSTDRQVKLYKEILMELNGAALEGEFKECYKLDNGDIISFI
>NC_013940.1|WP_013008929.1|78607_81013_-|CRISPR-associated-helicase/endonuclease-Cas3
MATKSGLLSHPDKQLEDHISNVIKLVNNFYDNTKLNDNILKNILTIISFAHDVGKATTAFQEYIKGNSELKNKPETTHSLFGACISLYLTDRYLKSINQNNDFLLFLSFVIPRLHHSNLVDVYQITLLDENQIELLTTQLNLLKINQDQFYQFIENTKINNKDLIKFNLNEINFNNIILLIRQINKFIKNIRTTVNGLNKTNILLKSRINSKPINIDYYIIVSLLYSILIDADKSDAGIKADKNILFKRDNLSSEIIDNFINTLKFKKTDIVKLRQQAFQEITTKDIDINNKIYTLTLPTGLGKTLLSFKLALKLSNKIKEEKNVIPKIIYCLPFLSVIEQNYNVIKSVLETNNIKVDNSILIKHHYLTDMTYTYQNDEFEYDTSKLLIEGWNGQIITTTFLQFFYSLIGNKNKMLRKFHKLTNSIVILDEIQSIPQKYWLLLKEVLNKMAEKFNFYVILTTATQPMIFDKKQYIELASNNYFDKLDRYVVNINKDLKTVDEFYYSLNIEKNKTYLFIMNTVNSAKRLYELLKKEYKNDILFLSTHITPKERLKRIQQIKNNDKRIVVSTQLVEAGVDIDFDVVYRDFAPLDSLIQSAGRCNRNGEKTTGIFNILKLYNENHQGRLYGSYIYDTLLLTATEQILDKEFFTEPEFIQLTNKYFQKVNEIKSNSDSLELLKILSELKFTYEKDNNKITSVEDFKLINNNYPRIDVFIQLDDTAVTIWKEYIKISNIKDYLERKRLFNNIKKDFFEYIISVPIKDNMNIPPIENNFYYVPIDNLDDYYDYETGFKTDSNLYIAL
>NC_013940.1|WP_013008928.1|77148_77820_+|hypothetical-protein
MKNINSDITQQDIIDNFQNLYANFLQKIDNLIQDNLDNITSNTINHLYYLQFNLLKNFKGNSSGFTGLSEFLIVRFIIHYITKKYNQNFKLLPITKDIKYWQSQNFKINVQQTIKLPKPVKVGNKKQNKIQPDIIIKKENKIISYIEIKIYLKDFKILEDLIKKYEVLLENNKNNYKLLFILFNGNDNIMEKLDKYKLQNTWFNYIVLNKSNKKFIDAVNKIV
>NC_013940.1|WP_013008927.1|76161_77127_+|tyrosine-type-recombinase/integrase
MELEPLIKDNLVNDLIRWKKLFIEDLRVRNYSNNTIELYSKEIDYFIEYSRGYVDEMDINDINRPYIQGSLAYREEISIKDSISSNTKQIYIKALKQFFIFITENNREYKDYTTIFRKIKIVTQTKEKEYLTEQEISKLLNYLEVLKSRRESIVTFRNVFLIKLLLYSGLRISEALQLKFTDFEEIAINNTYYYQIKVKGKGQTESYAYVPKELIEDEYLYLSESYSNKHNNIFITRNGSILKRQDAYKIITNIYKKAGINKTGIHLLRHTFAMKLVNAGVDLLHIKELLRHKNVNSTLVYAKSTQQMVDESFKKSILNKD
>NC_013940.1|WP_013008926.1|75652_75883_-|hypothetical-protein
MSELKNNITNKNNTTEFVNKRIDLTKKSLKQIKIIASILDDNVDNKFDKNTISYIINKAVNHYFNSEEIQNQLKEL
>NC_013940.1|WP_013008925.1|75257_75596_-|hypothetical-protein
MLNTDKELITILELTKIETLPPKDDDRLIILSQEVTKMIYSYLNIQKITEFELWNTYFSKYMKYENFLSCLQNSQGKYKYIKYILSFYRYITNKTYNLSTNSSLINNHSIIT
>NC_013940.1|WP_013008924.1|73658_75251_+|bacteriohemerythrin
MKINLKIKISLGILFVGILGGIIGLFNIYGISNNISLSLLIKLDLFLMFLGTVSAVAIIIYLNSYIFKNLNVLKRNIANISQGILEFENMNNKSKDELSETVSNMYKSCIKISDILKEFFKTSLELKSASEDLANASDEAHKNLTELNDEVQSISTAAEELNSTSKNIYDNSVEIVESITNSESKLNDSINIISENKEQVEKVAETSSLVVEKVTEFRKLSEEISRIVSTINEIADQTNLLALNAAIEAARAGEHGRGFAVVADEVRKLANKTTDSTKLIEEAIKSIQQEADDISNVVMKEQEEVKNSVTKVNESIESINLVKESFNDVKLRVESITNAINEESLAIEDITRNITNVSYKLNEIKNIVDKTQQSSGELLEISVQLMENISFFKIDYKGKFIEWSDKLSVGIDKFDEQHKNLVRLVNEIYDAVNADKSAVVLEKILNELVEYTVYHFNSEEEAFKRFEYPEYEKHREIHEDLKEQVGEFLERYKKGDTAIGFNLLNFLKKWLVNHIMGEDKKYGAFLKGKI
>NC_013940.1|WP_153801540.1|86846_87746_+|nucleotidyl-transferase-AbiEii/AbiGii-toxin-family-protein
MKRNAKSKSRGKNMEYKKFSNNITSTNITDDNFDWEHLLNVACKFHKIFPDGILIGGSVASIYAMHRVSFDIDFVFNDLKEKFEKFIDILEKGEIEVDNVKEEWEWELARMAKGKVILGNFDGVETGLRQLMRTKPLETTLYEVKPGKFIKIPTIEETLRTKAWMILSRNATRDYLDFCALAKQLYSEDPARLIKAMESFDDYYIDMYDKLKKRKPENKKSPLLQLLKQLAEPKPFDLNKIDLKKYKGIVKPWTEWKNIKKISQDAAVVLTEALTGIEPTFKKEIETKVKRDNDNLMEL
>NC_013940.1|WP_013008935.1|87747_88086_+|hypothetical-protein
MSNKNYENTKFTYRNIDKIDDMPETIEEVVSIFERGNDNQIIKLLALCQKEPFSEIANLVLDVCDYMEDNPEHAVYGLPTLFKKTILYYRNESKLESDLDKPFDNSLDDLNI
>NC_013940.1|WP_013008936.1|88195_88540_+|hypothetical-protein
MRKLFLVLTSFIILAMVIGCSGSSITMDDLKMLYPFFRDTKLQCSLDGNEVKCFDKRDKSNVVFYLNEKNIITKVVLKLKKGADVTITEKGKILKLIDEANSDYYRRKNTRRLF
>NC_013940.1|WP_013008937.1|88577_88898_+|hypothetical-protein
MSHVPEKNNVKMDYPLLFSAAEFLIGLTGAFGAIFVIMSLIPAIRYGLNFYALLSAILSLLGIILGMGIGFAFMRMVAASIDTRNYLYDIYLELKNLDKKTETKQE
>NC_013940.1|WP_013008938.1|88956_89433_+|hypothetical-protein
MKKLLVIFGLTTFLLVNNLFSVSYATENKTKTSEKPYYIIFDKNFIEHSLKGLTGCKILKVGKGDVSSYGITDFEYMSSTVDRKKGLPVKLYKFITNSLEIEKKYVQKRGYNALIVQDVEYVYGFDTNDSMSIINGKVGSRSLAVAVVYVDALIKCRN
>NC_013940.1|WP_013008939.1|89578_90187_+|hypothetical-protein
MSNFYIEVYEDNELIKIIDFHLPSNPYSYSYSKKKILNKIKNTKANYNFYLDVCSIAEIFFTPPNLLKNSEYILATESFTEGSFTTVLDDDKFDSKKLLIVMVTLERWSIDGFIWKVFYGEDAKVFGKKLEELMCKYDTDLETEKTNLQLFEEDYIKTGKYQELLKQYNIKEINLNKININKKPNKEKTQNLSLHHPQDTFF
>NC_013940.1|WP_013008940.1|90358_91411_-|hypothetical-protein
MAKVLKPLNVSTQYIKEIDNLTDTDMVNLEPIDLKQMKNLLFNNKNHLNFNKAIAEKILNYFQQSLRDLAKLDLNTKDDKLKFIKLLALNNYFIEYRLEDLLNHLTPKEKDAFIKNYMKSYEQVQDIYKENQHDFKYYLEEAITDLGIDTFENYLNIDKGNMIKNVVFNNLLHTEESLSNLIGNLINFFDGMTPIMILGSAFIKNNLQILDGSQNEEKLVNEILNLNVDDEIKQYLLMDLFNKDIMEYRQENNKFIEQNSQLYNLYIDAFKSVGIDLEKELDKVSRLAQKDPDFDLNNPKNLNKLDTVTLTALNFYKTVRQRFSMDQKDDLKFNDPTSFFAPKPDRDLSM
>NC_013940.1|WP_013008941.1|91448_92045_-|hypothetical-protein
MKVIDKEKKKNIKNLYITTNDELLYFQNETEQTKDNNIYISQLQKLQQKALNKLRQLQKINKKIPGEYLVTLEYITPIDNNPNKYKTLIDTFKLMYEENSVPKYDINKRLLNTFYYVYDEINDKFTSKLVIAIETTLDKKTLNYSILYRSSDLTSEKLIQVMDEIKQVIDNYVFEITPETNNINLKQIDTSYNQDLSL
>NC_013940.1|WP_013008942.1|92213_94121_+|hypothetical-protein
MFENFKDNYNIKQNKKFQKNYNNTYNNELNKIYSNFITSLIKTFDQNAKESQTVFRNFDIKVPMANIKGKRFIQTAADKNNNFKMVFIDYVWNDFVKRADIDSISKAIISSVKNIISSDKYNNVFALWKQVNNLLSDPLKYMVQNKNEEIKVRNILVSRIIKTINDFINNNTDRLFNKFSEIHSKEQNMIQKNATSIKANIRKHLTSMFKNSMMGMSTESFIGIKTAVNYIYTTSILNTKENISQNDILTKYPLLFKIYKNLDKLKNNPDSYKMLFNVIYENQPDVLNVINNQINNIEKQFESFNNPYYMYYKKYISFLKAYFTYQHNVLKICKNYVNNKIDRETLNKLLNKIKVNFETEKFTLQDFYTKVLKMNTINPTIVNSLAHILETFFVHQPVIPEFLAYEYKHLIDFFEPVLPSESKLFMKQDPLSNFLDKVLGEDKPTKQDSDNEIKERGKIIDALLDLVKDNNIPINDKEIEEEMKKYGLDTSDPEKIIEFKKELLSKNIIPTLEQTNYQIFSMIQDIKSLISSTIYANYVTLTDLNKFKNLNDFYEIDIERRFLNLNYKYPLVDINEIIEKETTNEKKTSTLYLDKFITLSCYLNYISKLILKELNKQKPEVSKDLGYNAEMNLNY
>NC_013940.1|WP_013008943.1|94289_95093_+|hypothetical-protein
MSQKYKYSDITLKLMVLIYYLFSLLYVFINIDLKYILDTKVIGFVLINLFLFNQIVIKKSFNKTYRDVVYGFLNTLILTIFAMMFFAMCLKFFIHIVYLKYVLFNFLLLQMILIVSYYLIINKSYIKGYLTFIFLFSIFIIYTLNQIYNYDNVIYLSLFLSTIILIVSINLIGYKYLRFYLIHKNRLMYQILFYYNQLMNGKQATQTTNELWKDIFIFSYKKHIENKYYIYLDNLVKNNIYFYIDLLSHSITFIKYLSLHHPQDTFF

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NC_013940_1	1.1\|77908\|38\|NC_013940\|CRISPRCasFinder,CRT	77908-77945	38	NC_013940	Deferribacter desulfuricans SSM1 megaplasmid pDF308, complete sequence	77908-77945	0	1.0
NC_013940_1	1.1\|77908\|38\|NC_013940\|CRISPRCasFinder,CRT	77908-77945	38	NC_013940	Deferribacter desulfuricans SSM1 megaplasmid pDF308, complete sequence	85588-85625	0	1.0
NC_013940_1	1.2\|77976\|36\|NC_013940\|CRISPRCasFinder,CRT,PILER-CR	77976-78011	36	NC_013940	Deferribacter desulfuricans SSM1 megaplasmid pDF308, complete sequence	77976-78011	0	1.0
NC_013940_1	1.3\|78042\|38\|NC_013940\|CRISPRCasFinder,CRT,PILER-CR	78042-78079	38	NC_013940	Deferribacter desulfuricans SSM1 megaplasmid pDF308, complete sequence	78042-78079	0	1.0
NC_013940_1	1.4\|78110\|36\|NC_013940\|CRISPRCasFinder,CRT,PILER-CR	78110-78145	36	NC_013940	Deferribacter desulfuricans SSM1 megaplasmid pDF308, complete sequence	78110-78145	0	1.0
NC_013940_1	1.5\|78176\|35\|NC_013940\|CRISPRCasFinder,CRT,PILER-CR	78176-78210	35	NC_013940	Deferribacter desulfuricans SSM1 megaplasmid pDF308, complete sequence	78176-78210	0	1.0
NC_013940_1	1.6\|78241\|38\|NC_013940\|CRISPRCasFinder,CRT,PILER-CR	78241-78278	38	NC_013940	Deferribacter desulfuricans SSM1 megaplasmid pDF308, complete sequence	78241-78278	0	1.0
NC_013940_1	1.7\|78309\|37\|NC_013940\|CRISPRCasFinder,CRT,PILER-CR	78309-78345	37	NC_013940	Deferribacter desulfuricans SSM1 megaplasmid pDF308, complete sequence	78309-78345	0	1.0
NC_013940_2	2.1\|85588\|38\|NC_013940\|CRISPRCasFinder,CRT	85588-85625	38	NC_013940	Deferribacter desulfuricans SSM1 megaplasmid pDF308, complete sequence	77908-77945	0	1.0
NC_013940_2	2.1\|85588\|38\|NC_013940\|CRISPRCasFinder,CRT	85588-85625	38	NC_013940	Deferribacter desulfuricans SSM1 megaplasmid pDF308, complete sequence	85588-85625	0	1.0
NC_013940_2	2.2\|85656\|37\|NC_013940\|CRISPRCasFinder,CRT,PILER-CR	85656-85692	37	NC_013940	Deferribacter desulfuricans SSM1 megaplasmid pDF308, complete sequence	85656-85692	0	1.0
NC_013940_2	2.3\|85723\|36\|NC_013940\|CRISPRCasFinder,CRT,PILER-CR	85723-85758	36	NC_013940	Deferribacter desulfuricans SSM1 megaplasmid pDF308, complete sequence	85723-85758	0	1.0
NC_013940_2	2.4\|85789\|37\|NC_013940\|CRISPRCasFinder,CRT,PILER-CR	85789-85825	37	NC_013940	Deferribacter desulfuricans SSM1 megaplasmid pDF308, complete sequence	85789-85825	0	1.0
NC_013940_2	2.5\|85856\|35\|NC_013940\|CRISPRCasFinder,CRT,PILER-CR	85856-85890	35	NC_013940	Deferribacter desulfuricans SSM1 megaplasmid pDF308, complete sequence	85856-85890	0	1.0
NC_013940_2	2.6\|85921\|37\|NC_013940\|CRISPRCasFinder,CRT,PILER-CR	85921-85957	37	NC_013940	Deferribacter desulfuricans SSM1 megaplasmid pDF308, complete sequence	85921-85957	0	1.0
NC_013940_2	2.7\|85988\|39\|NC_013940\|CRISPRCasFinder,CRT,PILER-CR	85988-86026	39	NC_013940	Deferribacter desulfuricans SSM1 megaplasmid pDF308, complete sequence	85988-86026	0	1.0
NC_013940_2	2.8\|86057\|34\|NC_013940\|CRISPRCasFinder,CRT,PILER-CR	86057-86090	34	NC_013940	Deferribacter desulfuricans SSM1 megaplasmid pDF308, complete sequence	86057-86090	0	1.0
NC_013940_2	2.9\|86121\|37\|NC_013940\|CRISPRCasFinder,CRT,PILER-CR	86121-86157	37	NC_013940	Deferribacter desulfuricans SSM1 megaplasmid pDF308, complete sequence	86121-86157	0	1.0
NC_013940_2	2.10\|86188\|36\|NC_013940\|CRISPRCasFinder,CRT,PILER-CR	86188-86223	36	NC_013940	Deferribacter desulfuricans SSM1 megaplasmid pDF308, complete sequence	86188-86223	0	1.0
NC_013940_2	2.11\|86254\|37\|NC_013940\|CRISPRCasFinder,CRT,PILER-CR	86254-86290	37	NC_013940	Deferribacter desulfuricans SSM1 megaplasmid pDF308, complete sequence	86254-86290	0	1.0
NC_013940_2	2.12\|86321\|37\|NC_013940\|CRISPRCasFinder,CRT,PILER-CR	86321-86357	37	NC_013940	Deferribacter desulfuricans SSM1 megaplasmid pDF308, complete sequence	86321-86357	0	1.0
NC_013940_2	2.8\|86057\|34\|NC_013940\|CRISPRCasFinder,CRT,PILER-CR	86057-86090	34	MG592566	Vibrio phage 1.197.A._10N.286.54.F2, partial genome	13446-13479	7	0.794
NC_013940_2	2.8\|86057\|34\|NC_013940\|CRISPRCasFinder,CRT,PILER-CR	86057-86090	34	MT438761	Listeria virus P61, complete genome	116400-116433	8	0.765
NC_013940_1	1.4\|78110\|36\|NC_013940\|CRISPRCasFinder,CRT,PILER-CR	78110-78145	36	NZ_KY303941	Enterococcus faecalis strain 3 plasmid pGTC3, complete sequence	80766-80801	9	0.75
NC_013940_2	2.8\|86057\|34\|NC_013940\|CRISPRCasFinder,CRT,PILER-CR	86057-86090	34	MG592465	Vibrio phage 1.090.B._10N.286.48.F1, partial genome	12774-12807	9	0.735
NC_013940_2	2.8\|86057\|34\|NC_013940\|CRISPRCasFinder,CRT,PILER-CR	86057-86090	34	MT511058	Escherichia phage vB_EcoD_SU57, complete genome	29515-29548	9	0.735
NC_013940_2	2.8\|86057\|34\|NC_013940\|CRISPRCasFinder,CRT,PILER-CR	86057-86090	34	NZ_LT599052	Lactococcus lactis subsp. lactis strain A12 plasmid pA12-3, complete sequence	26180-26213	9	0.735
NC_013940_2	2.11\|86254\|37\|NC_013940\|CRISPRCasFinder,CRT,PILER-CR	86254-86290	37	NZ_CP020607	Lactococcus lactis subsp. lactis bv. diacetylactis strain FM03 plasmid pLd3, complete sequence	129-165	9	0.757
NC_013940_2	2.8\|86057\|34\|NC_013940\|CRISPRCasFinder,CRT,PILER-CR	86057-86090	34	MN694754	Marine virus AFVG_250M450, complete genome	8380-8413	10	0.706
NC_013940_2	2.8\|86057\|34\|NC_013940\|CRISPRCasFinder,CRT,PILER-CR	86057-86090	34	MN693398	Marine virus AFVG_25M63, complete genome	56005-56038	10	0.706
NC_013940_1	1.5\|78176\|35\|NC_013940\|CRISPRCasFinder,CRT,PILER-CR	78176-78210	35	NC_019526	Enterobacteria phage vB_KleM-RaK2, complete genome	182513-182547	11	0.686
NC_013940_2	2.8\|86057\|34\|NC_013940\|CRISPRCasFinder,CRT,PILER-CR	86057-86090	34	MK448824	Streptococcus phage Javan637, complete genome	39404-39437	11	0.676
NC_013940_2	2.8\|86057\|34\|NC_013940\|CRISPRCasFinder,CRT,PILER-CR	86057-86090	34	MK449002	Streptococcus phage Javan642, complete genome	39359-39392	11	0.676
NC_013940_2	2.8\|86057\|34\|NC_013940\|CRISPRCasFinder,CRT,PILER-CR	86057-86090	34	MK449003	Streptococcus phage Javan648, complete genome	39359-39392	11	0.676
NC_013940_2	2.8\|86057\|34\|NC_013940\|CRISPRCasFinder,CRT,PILER-CR	86057-86090	34	MN692986	Marine virus AFVG_117M62, complete genome	8673-8706	13	0.618
NC_013940_2	2.12\|86321\|37\|NC_013940\|CRISPRCasFinder,CRT,PILER-CR	86321-86357	37	MK448993	Streptococcus phage Javan616, complete genome	35749-35785	13	0.649

1. spacer 1.1|77908|38|NC_013940|CRISPRCasFinder,CRT matches to NC_013940 (Deferribacter desulfuricans SSM1 megaplasmid pDF308, complete sequence) position: , mismatch: 0, identity: 1.0

agaacacctaaaataattaccacaactataacttctgt	CRISPR spacer
agaacacctaaaataattaccacaactataacttctgt	Protospacer
**************************************

2. spacer 1.1|77908|38|NC_013940|CRISPRCasFinder,CRT matches to NC_013940 (Deferribacter desulfuricans SSM1 megaplasmid pDF308, complete sequence) position: , mismatch: 0, identity: 1.0

agaacacctaaaataattaccacaactataacttctgt	CRISPR spacer
agaacacctaaaataattaccacaactataacttctgt	Protospacer
**************************************

3. spacer 1.2|77976|36|NC_013940|CRISPRCasFinder,CRT,PILER-CR matches to NC_013940 (Deferribacter desulfuricans SSM1 megaplasmid pDF308, complete sequence) position: , mismatch: 0, identity: 1.0

aaaaatcaccattacatcatttattgcttttgtaat	CRISPR spacer
aaaaatcaccattacatcatttattgcttttgtaat	Protospacer
************************************

4. spacer 1.3|78042|38|NC_013940|CRISPRCasFinder,CRT,PILER-CR matches to NC_013940 (Deferribacter desulfuricans SSM1 megaplasmid pDF308, complete sequence) position: , mismatch: 0, identity: 1.0

actgattattttgagatatggtgggatgcagataaatt	CRISPR spacer
actgattattttgagatatggtgggatgcagataaatt	Protospacer
**************************************

5. spacer 1.4|78110|36|NC_013940|CRISPRCasFinder,CRT,PILER-CR matches to NC_013940 (Deferribacter desulfuricans SSM1 megaplasmid pDF308, complete sequence) position: , mismatch: 0, identity: 1.0

aaagtttaataaaaaggaaagatgtgtcggatataa	CRISPR spacer
aaagtttaataaaaaggaaagatgtgtcggatataa	Protospacer
************************************

6. spacer 1.5|78176|35|NC_013940|CRISPRCasFinder,CRT,PILER-CR matches to NC_013940 (Deferribacter desulfuricans SSM1 megaplasmid pDF308, complete sequence) position: , mismatch: 0, identity: 1.0

tgaaatgatgtatttgatgaaagtgatacaacgtg	CRISPR spacer
tgaaatgatgtatttgatgaaagtgatacaacgtg	Protospacer
***********************************

7. spacer 1.6|78241|38|NC_013940|CRISPRCasFinder,CRT,PILER-CR matches to NC_013940 (Deferribacter desulfuricans SSM1 megaplasmid pDF308, complete sequence) position: , mismatch: 0, identity: 1.0

gtgcttagtaatactaatacacaaatatttttgaaaac	CRISPR spacer
gtgcttagtaatactaatacacaaatatttttgaaaac	Protospacer
**************************************

8. spacer 1.7|78309|37|NC_013940|CRISPRCasFinder,CRT,PILER-CR matches to NC_013940 (Deferribacter desulfuricans SSM1 megaplasmid pDF308, complete sequence) position: , mismatch: 0, identity: 1.0

agctcaacaaaaatagcataactactagctgtaagcg	CRISPR spacer
agctcaacaaaaatagcataactactagctgtaagcg	Protospacer
*************************************

9. spacer 2.1|85588|38|NC_013940|CRISPRCasFinder,CRT matches to NC_013940 (Deferribacter desulfuricans SSM1 megaplasmid pDF308, complete sequence) position: , mismatch: 0, identity: 1.0

agaacacctaaaataattaccacaactataacttctgt	CRISPR spacer
agaacacctaaaataattaccacaactataacttctgt	Protospacer
**************************************

10. spacer 2.1|85588|38|NC_013940|CRISPRCasFinder,CRT matches to NC_013940 (Deferribacter desulfuricans SSM1 megaplasmid pDF308, complete sequence) position: , mismatch: 0, identity: 1.0

agaacacctaaaataattaccacaactataacttctgt	CRISPR spacer
agaacacctaaaataattaccacaactataacttctgt	Protospacer
**************************************

11. spacer 2.2|85656|37|NC_013940|CRISPRCasFinder,CRT,PILER-CR matches to NC_013940 (Deferribacter desulfuricans SSM1 megaplasmid pDF308, complete sequence) position: , mismatch: 0, identity: 1.0

aaatatggtaaactaaaagttgatgattacgtatata	CRISPR spacer
aaatatggtaaactaaaagttgatgattacgtatata	Protospacer
*************************************

12. spacer 2.3|85723|36|NC_013940|CRISPRCasFinder,CRT,PILER-CR matches to NC_013940 (Deferribacter desulfuricans SSM1 megaplasmid pDF308, complete sequence) position: , mismatch: 0, identity: 1.0

gatattctttgcagtatacacctttatatttaaacc	CRISPR spacer
gatattctttgcagtatacacctttatatttaaacc	Protospacer
************************************

13. spacer 2.4|85789|37|NC_013940|CRISPRCasFinder,CRT,PILER-CR matches to NC_013940 (Deferribacter desulfuricans SSM1 megaplasmid pDF308, complete sequence) position: , mismatch: 0, identity: 1.0

ttgataaatcagttggaccagaaattaatttcattag	CRISPR spacer
ttgataaatcagttggaccagaaattaatttcattag	Protospacer
*************************************

14. spacer 2.5|85856|35|NC_013940|CRISPRCasFinder,CRT,PILER-CR matches to NC_013940 (Deferribacter desulfuricans SSM1 megaplasmid pDF308, complete sequence) position: , mismatch: 0, identity: 1.0

ctcatccaattcctaagtgtgaatttgctaacctt	CRISPR spacer
ctcatccaattcctaagtgtgaatttgctaacctt	Protospacer
***********************************

15. spacer 2.6|85921|37|NC_013940|CRISPRCasFinder,CRT,PILER-CR matches to NC_013940 (Deferribacter desulfuricans SSM1 megaplasmid pDF308, complete sequence) position: , mismatch: 0, identity: 1.0

tagaaacaaattttttggagcatgctgcaagaggtgt	CRISPR spacer
tagaaacaaattttttggagcatgctgcaagaggtgt	Protospacer
*************************************

16. spacer 2.7|85988|39|NC_013940|CRISPRCasFinder,CRT,PILER-CR matches to NC_013940 (Deferribacter desulfuricans SSM1 megaplasmid pDF308, complete sequence) position: , mismatch: 0, identity: 1.0

ttgcacaagcatatccttgcgcatgtaccaagcctcttt	CRISPR spacer
ttgcacaagcatatccttgcgcatgtaccaagcctcttt	Protospacer
***************************************

17. spacer 2.8|86057|34|NC_013940|CRISPRCasFinder,CRT,PILER-CR matches to NC_013940 (Deferribacter desulfuricans SSM1 megaplasmid pDF308, complete sequence) position: , mismatch: 0, identity: 1.0

tgcttttgctgttgtttttgttgctgttgtttta	CRISPR spacer
tgcttttgctgttgtttttgttgctgttgtttta	Protospacer
**********************************

18. spacer 2.9|86121|37|NC_013940|CRISPRCasFinder,CRT,PILER-CR matches to NC_013940 (Deferribacter desulfuricans SSM1 megaplasmid pDF308, complete sequence) position: , mismatch: 0, identity: 1.0

taactattgatgatatattctgttttgttgtgcctgt	CRISPR spacer
taactattgatgatatattctgttttgttgtgcctgt	Protospacer
*************************************

19. spacer 2.10|86188|36|NC_013940|CRISPRCasFinder,CRT,PILER-CR matches to NC_013940 (Deferribacter desulfuricans SSM1 megaplasmid pDF308, complete sequence) position: , mismatch: 0, identity: 1.0

ttatatttttgtataaattatatgtatatgcatatt	CRISPR spacer
ttatatttttgtataaattatatgtatatgcatatt	Protospacer
************************************

20. spacer 2.11|86254|37|NC_013940|CRISPRCasFinder,CRT,PILER-CR matches to NC_013940 (Deferribacter desulfuricans SSM1 megaplasmid pDF308, complete sequence) position: , mismatch: 0, identity: 1.0

gcttcagcaattccatacttatcacttatttttattg	CRISPR spacer
gcttcagcaattccatacttatcacttatttttattg	Protospacer
*************************************

21. spacer 2.12|86321|37|NC_013940|CRISPRCasFinder,CRT,PILER-CR matches to NC_013940 (Deferribacter desulfuricans SSM1 megaplasmid pDF308, complete sequence) position: , mismatch: 0, identity: 1.0

tgtatttttcaaagtttttatcttttgtaacaaattc	CRISPR spacer
tgtatttttcaaagtttttatcttttgtaacaaattc	Protospacer
*************************************

22. spacer 2.8|86057|34|NC_013940|CRISPRCasFinder,CRT,PILER-CR matches to MG592566 (Vibrio phage 1.197.A._10N.286.54.F2, partial genome) position: , mismatch: 7, identity: 0.794

tgcttttgctgttgtttttgttgctgttgtttta	CRISPR spacer
ttatattgctgttgtgtttgttgctgctgttgtt	Protospacer
*  * ********** **********.**** *

23. spacer 2.8|86057|34|NC_013940|CRISPRCasFinder,CRT,PILER-CR matches to MT438761 (Listeria virus P61, complete genome) position: , mismatch: 8, identity: 0.765

tgcttttgctgttgtttttgttgctgttgtttta	CRISPR spacer
tgtgcttgctgttgttgttgttgttgttgtactg	Protospacer
**. .*********** ******.****** .*.

24. spacer 1.4|78110|36|NC_013940|CRISPRCasFinder,CRT,PILER-CR matches to NZ_KY303941 (Enterococcus faecalis strain 3 plasmid pGTC3, complete sequence) position: , mismatch: 9, identity: 0.75

aaagtttaataaaaaggaaagatgtgtcggatataa	CRISPR spacer
tcagtttcataaaaaggaaggatgtgtcctagttta	Protospacer
  ***** ***********.********  *  * *

25. spacer 2.8|86057|34|NC_013940|CRISPRCasFinder,CRT,PILER-CR matches to MG592465 (Vibrio phage 1.090.B._10N.286.48.F1, partial genome) position: , mismatch: 9, identity: 0.735

---tgcttttgctgttgtttttgttgctgttgtttta	CRISPR spacer
tgttgctgctgttgttgttgttgttgttgttgat---	Protospacer
   **** .**.******* ******.***** *

26. spacer 2.8|86057|34|NC_013940|CRISPRCasFinder,CRT,PILER-CR matches to MT511058 (Escherichia phage vB_EcoD_SU57, complete genome) position: , mismatch: 9, identity: 0.735

---tgcttttgctgttgtttttgttgctgttgtttta	CRISPR spacer
tgttgctgttgttgttgttgttgctgttgttgct---	Protospacer
   **** ***.******* ***.**.*****.*

27. spacer 2.8|86057|34|NC_013940|CRISPRCasFinder,CRT,PILER-CR matches to NZ_LT599052 (Lactococcus lactis subsp. lactis strain A12 plasmid pA12-3, complete sequence) position: , mismatch: 9, identity: 0.735

tgcttttgctgttgtttttgttgctgttgtttta	CRISPR spacer
tcgtgttgctgttgcttgtgttgctgttgctcgt	Protospacer
*  * *********.** ***********.*.

28. spacer 2.11|86254|37|NC_013940|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP020607 (Lactococcus lactis subsp. lactis bv. diacetylactis strain FM03 plasmid pLd3, complete sequence) position: , mismatch: 9, identity: 0.757

gcttcagcaattccatacttatcacttatttt-tattg	CRISPR spacer
aatgtcgcaattccaaacttatcatttattttatgtt-	Protospacer
. * . ********* ********.******* *.**

29. spacer 2.8|86057|34|NC_013940|CRISPRCasFinder,CRT,PILER-CR matches to MN694754 (Marine virus AFVG_250M450, complete genome) position: , mismatch: 10, identity: 0.706

tgcttttgctgttgtttttgttgctgttgtttta	CRISPR spacer
tccagcggctgttgttgctgttgctgttgttgcg	Protospacer
* *  . ********* .************* ..

30. spacer 2.8|86057|34|NC_013940|CRISPRCasFinder,CRT,PILER-CR matches to MN693398 (Marine virus AFVG_25M63, complete genome) position: , mismatch: 10, identity: 0.706

tgcttttgctgttgtttttgttgctgttgtttta	CRISPR spacer
tttactctctgttgtttctgtagctgttgtttct	Protospacer
* . .*. *********.*** **********.

31. spacer 1.5|78176|35|NC_013940|CRISPRCasFinder,CRT,PILER-CR matches to NC_019526 (Enterobacteria phage vB_KleM-RaK2, complete genome) position: , mismatch: 11, identity: 0.686

tgaaatgatgtatttgatgaaagtgatacaacgtg	CRISPR spacer
aagaatgatgaattttatgaaagtgatatagatga	Protospacer
 ..******* **** ************.*.   .

32. spacer 2.8|86057|34|NC_013940|CRISPRCasFinder,CRT,PILER-CR matches to MK448824 (Streptococcus phage Javan637, complete genome) position: , mismatch: 11, identity: 0.676

tgcttttgctgttgtttttgttgctgttgtttta	CRISPR spacer
aatttttactgttgtttttggtgctgtatgcaca	Protospacer
 ..****.************ ******   . .*

33. spacer 2.8|86057|34|NC_013940|CRISPRCasFinder,CRT,PILER-CR matches to MK449002 (Streptococcus phage Javan642, complete genome) position: , mismatch: 11, identity: 0.676

tgcttttgctgttgtttttgttgctgttgtttta	CRISPR spacer
aatttttactgttgtttttggtgctgtatgcaca	Protospacer
 ..****.************ ******   . .*

34. spacer 2.8|86057|34|NC_013940|CRISPRCasFinder,CRT,PILER-CR matches to MK449003 (Streptococcus phage Javan648, complete genome) position: , mismatch: 11, identity: 0.676

tgcttttgctgttgtttttgttgctgttgtttta	CRISPR spacer
aatttttactgttgtttttggtgctgtatgcaca	Protospacer
 ..****.************ ******   . .*

35. spacer 2.8|86057|34|NC_013940|CRISPRCasFinder,CRT,PILER-CR matches to MN692986 (Marine virus AFVG_117M62, complete genome) position: , mismatch: 13, identity: 0.618

tgcttttgctgttgtttttgttgctgttgtttta---	CRISPR spacer
---ctttgttgctgttgttgctgttgctgttgagtat	Protospacer
   .****.**.**** ***.**.**.****  .

36. spacer 2.12|86321|37|NC_013940|CRISPRCasFinder,CRT,PILER-CR matches to MK448993 (Streptococcus phage Javan616, complete genome) position: , mismatch: 13, identity: 0.649

tgtatttttcaaagtttttatcttttgtaacaaattc	CRISPR spacer
cagtgttttcaaggttttcatcttttgtaacctcgct	Protospacer
..   *******.*****.************    ..

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

548 : 64201

Helicobacter_phage(35.71%)

transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_013008875.1\|548_974_-\|transposase	IS200/IS605 family transposase	A0A1S5RHE3	Helicobacter_phage	2.6e-48	67.9
WP_013008876.1\|996_2328_+\|transposase	transposase	A0A1B0VCD8	Salmonella_phage	9.8e-86	45.6
WP_041224012.1\|2452_2806_+	hypothetical protein	NA	NA	NA	NA
WP_013008877.1\|2868_3534_+	hypothetical protein	NA	NA	NA	NA
WP_013008878.1\|3646_4219_+	hypothetical protein	NA	NA	NA	NA
WP_013008879.1\|4242_4461_+	hypothetical protein	NA	NA	NA	NA
WP_013008880.1\|4520_4808_+	late competence development ComFB family protein	NA	NA	NA	NA
WP_013008881.1\|4861_6979_+	type I DNA topoisomerase	M1PXL0	Moumouvirus	4.0e-57	30.6
WP_013008882.1\|7091_10115_+	hypothetical protein	NA	NA	NA	NA
WP_013008883.1\|10141_11395_+	hypothetical protein	NA	NA	NA	NA
WP_013008884.1\|11509_11881_+	hypothetical protein	NA	NA	NA	NA
WP_013008885.1\|11906_13721_+	RepB family plasmid replication initiator protein	NA	NA	NA	NA
WP_013008886.1\|13717_14437_+	hypothetical protein	NA	NA	NA	NA
WP_013008887.1\|14460_16104_+	hypothetical protein	E3T4K4	Cafeteria_roenbergensis_virus	5.4e-09	23.9
WP_013008888.1\|16075_16606_+	redoxin domain-containing protein	NA	NA	NA	NA
WP_013008889.1\|16689_17178_+	prepilin-type N-terminal cleavage/methylation domain-containing protein	NA	NA	NA	NA
WP_013008890.1\|17225_18821_+	hypothetical protein	R9TEZ5	Vibrio_phage	6.6e-12	25.3
WP_013008891.1\|18880_20134_+	hypothetical protein	NA	NA	NA	NA
WP_013008892.1\|20157_20784_+	hypothetical protein	NA	NA	NA	NA
WP_013008893.1\|20801_21962_+	hypothetical protein	NA	NA	NA	NA
WP_013008894.1\|22008_23793_+	type II/IV secretion system protein	NA	NA	NA	NA
WP_013008895.1\|23816_24944_+	type II secretion system F family protein	NA	NA	NA	NA
WP_013008896.1\|24982_25378_+	hypothetical protein	NA	NA	NA	NA
WP_013008897.1\|25463_26315_-	hypothetical protein	NA	NA	NA	NA
WP_013008898.1\|26514_27015_+	hypothetical protein	NA	NA	NA	NA
WP_013008899.1\|27044_27758_+	hypothetical protein	NA	NA	NA	NA
WP_013008900.1\|27763_28696_+	hypothetical protein	NA	NA	NA	NA
WP_013008901.1\|28804_29176_+	hypothetical protein	NA	NA	NA	NA
WP_013008902.1\|29249_31229_+	type IV secretion system DNA-binding domain-containing protein	NA	NA	NA	NA
WP_013008903.1\|31218_31809_+	prepilin-type N-terminal cleavage/methylation domain-containing protein	NA	NA	NA	NA
WP_013008904.1\|31908_32316_+	PilZ domain-containing protein	NA	NA	NA	NA
WP_013008905.1\|32350_35575_+	hypothetical protein	NA	NA	NA	NA
WP_013008906.1\|35690_36338_+	EcsC family protein	NA	NA	NA	NA
WP_162527618.1\|36838_37138_+	hypothetical protein	NA	NA	NA	NA
WP_013008907.1\|37209_39102_+	hypothetical protein	NA	NA	NA	NA
WP_041224013.1\|39126_39609_+	hypothetical protein	NA	NA	NA	NA
WP_013008875.1\|39601_40027_-\|transposase	IS200/IS605 family transposase	A0A1S5RHE3	Helicobacter_phage	2.6e-48	67.9
WP_013008876.1\|40049_41381_+\|transposase	transposase	A0A1B0VCD8	Salmonella_phage	9.8e-86	45.6
WP_041224014.1\|41491_42643_+	hypothetical protein	NA	NA	NA	NA
WP_041224015.1\|42726_44847_+	hypothetical protein	NA	NA	NA	NA
WP_013008875.1\|44843_45269_-\|transposase	IS200/IS605 family transposase	A0A1S5RHE3	Helicobacter_phage	2.6e-48	67.9
WP_013008876.1\|45291_46623_+\|transposase	transposase	A0A1B0VCD8	Salmonella_phage	9.8e-86	45.6
WP_041224016.1\|46807_47035_+	hypothetical protein	NA	NA	NA	NA
WP_013008908.1\|47121_50715_+	metallophosphoesterase	W5QUL3	Bacillus_phage	1.3e-10	27.8
WP_041224017.1\|50823_51018_+	hypothetical protein	NA	NA	NA	NA
WP_013008875.1\|51014_51440_-\|transposase	IS200/IS605 family transposase	A0A1S5RHE3	Helicobacter_phage	2.6e-48	67.9
WP_013008876.1\|51462_52794_+\|transposase	transposase	A0A1B0VCD8	Salmonella_phage	9.8e-86	45.6
WP_041224018.1\|53024_53786_+	hypothetical protein	NA	NA	NA	NA
WP_013008909.1\|53865_54570_+	hypothetical protein	NA	NA	NA	NA
WP_013008910.1\|54599_54812_+	hypothetical protein	NA	NA	NA	NA
WP_013008911.1\|54838_56026_+	hypothetical protein	NA	NA	NA	NA
WP_013008912.1\|56097_58455_+	hypothetical protein	NA	NA	NA	NA
WP_013008913.1\|58475_60962_+	hypothetical protein	NA	NA	NA	NA
WP_050742541.1\|61098_61548_+	DUF4402 domain-containing protein	NA	NA	NA	NA
WP_013008914.1\|61664_62033_+	hypothetical protein	NA	NA	NA	NA
WP_013008915.1\|62071_62425_+	hypothetical protein	NA	NA	NA	NA
WP_013008875.1\|62421_62847_-\|transposase	IS200/IS605 family transposase	A0A1S5RHE3	Helicobacter_phage	2.6e-48	67.9
WP_013008876.1\|62869_64201_+\|transposase	transposase	A0A1B0VCD8	Salmonella_phage	9.8e-86	45.6

DBSCAN-SWA_2

76161 : 127789

Helicobacter_phage(38.46%)

integrase,transposase

attL 72638:72655|attR 107867:107884

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
72638:72655	attL	NA	NA	NA	NA
WP_013008927.1\|76161_77127_+\|integrase	tyrosine-type recombinase/integrase	A0A2L1IV36	Escherichia_phage	1.5e-11	29.9
WP_013008928.1\|77148_77820_+	hypothetical protein	NA	NA	NA	NA
WP_013008929.1\|78607_81013_-	CRISPR-associated helicase/endonuclease Cas3	A0A2R2ZGW0	Clostridioides_phage	1.8e-13	21.7
WP_013008930.1\|81034_81730_-	type I-B CRISPR-associated protein Cas5	NA	NA	NA	NA
WP_013008931.1\|81742_82651_-	type I-B CRISPR-associated protein Cas7/Csh2	NA	NA	NA	NA
WP_013008932.1\|82682_84569_-	TIGR02556 family CRISPR-associated protein	NA	NA	NA	NA
WP_013008933.1\|84608_85379_-	CRISPR-associated endoribonuclease Cas6	NA	NA	NA	NA
WP_153801540.1\|86846_87746_+	nucleotidyl transferase AbiEii/AbiGii toxin family protein	NA	NA	NA	NA
WP_013008935.1\|87747_88086_+	hypothetical protein	NA	NA	NA	NA
WP_013008936.1\|88195_88540_+	hypothetical protein	NA	NA	NA	NA
WP_013008937.1\|88577_88898_+	hypothetical protein	NA	NA	NA	NA
WP_013008938.1\|88956_89433_+	hypothetical protein	NA	NA	NA	NA
WP_013008939.1\|89578_90187_+	hypothetical protein	NA	NA	NA	NA
WP_013008940.1\|90358_91411_-	hypothetical protein	NA	NA	NA	NA
WP_013008941.1\|91448_92045_-	hypothetical protein	NA	NA	NA	NA
WP_013008942.1\|92213_94121_+	hypothetical protein	NA	NA	NA	NA
WP_013008943.1\|94289_95093_+	hypothetical protein	NA	NA	NA	NA
WP_013008875.1\|95089_95515_-\|transposase	IS200/IS605 family transposase	A0A1S5RHE3	Helicobacter_phage	2.6e-48	67.9
WP_013008876.1\|95537_96869_+\|transposase	transposase	A0A1B0VCD8	Salmonella_phage	9.8e-86	45.6
WP_041224019.1\|97087_102430_+	hypothetical protein	NA	NA	NA	NA
WP_013008875.1\|102426_102852_-\|transposase	IS200/IS605 family transposase	A0A1S5RHE3	Helicobacter_phage	2.6e-48	67.9
WP_013008876.1\|102874_104206_+\|transposase	transposase	A0A1B0VCD8	Salmonella_phage	9.8e-86	45.6
WP_041224020.1\|104783_106373_+	hypothetical protein	NA	NA	NA	NA
WP_161595895.1\|106741_108028_-	hypothetical protein	NA	NA	NA	NA
107867:107884	attR	NA	NA	NA	NA
WP_013008945.1\|108060_109554_-	hypothetical protein	NA	NA	NA	NA
WP_013008946.1\|109798_110332_+	hypothetical protein	NA	NA	NA	NA
WP_013008947.1\|110339_110951_-	hypothetical protein	NA	NA	NA	NA
WP_013008948.1\|111259_112015_-	hypothetical protein	NA	NA	NA	NA
WP_153801541.1\|112139_112484_-	hypothetical protein	NA	NA	NA	NA
WP_013008949.1\|112836_113592_+	hypothetical protein	NA	NA	NA	NA
WP_013008950.1\|113616_114318_+	metallophosphoesterase	A0A0K2FMM4	Mycobacterium_phage	4.5e-13	28.8
WP_161595896.1\|114369_114528_+	hypothetical protein	NA	NA	NA	NA
WP_013008951.1\|114514_114784_+	hypothetical protein	NA	NA	NA	NA
WP_013008875.1\|114780_115206_-\|transposase	IS200/IS605 family transposase	A0A1S5RHE3	Helicobacter_phage	2.6e-48	67.9
WP_013008876.1\|115228_116560_+\|transposase	transposase	A0A1B0VCD8	Salmonella_phage	9.8e-86	45.6
WP_013008952.1\|116597_117161_+	hypothetical protein	NA	NA	NA	NA
WP_013008953.1\|117305_117581_+	hypothetical protein	NA	NA	NA	NA
WP_013008954.1\|117613_118381_+	FliA/WhiG family RNA polymerase sigma factor	NA	NA	NA	NA
WP_013008875.1\|118557_118983_-\|transposase	IS200/IS605 family transposase	A0A1S5RHE3	Helicobacter_phage	2.6e-48	67.9
WP_013008876.1\|119005_120337_+\|transposase	transposase	A0A1B0VCD8	Salmonella_phage	9.8e-86	45.6
WP_013008955.1\|120470_121010_+	thermonuclease family protein	NA	NA	NA	NA
WP_013008956.1\|121138_123682_+	ATP-binding protein	NA	NA	NA	NA
WP_013008957.1\|123709_124006_+	hypothetical protein	NA	NA	NA	NA
WP_013008958.1\|124030_125107_+	hypothetical protein	NA	NA	NA	NA
WP_041224022.1\|125149_125794_+	hypothetical protein	NA	NA	NA	NA
WP_153801543.1\|125843_126017_+	hypothetical protein	NA	NA	NA	NA
WP_013008875.1\|126009_126435_-\|transposase	IS200/IS605 family transposase	A0A1S5RHE3	Helicobacter_phage	2.6e-48	67.9
WP_013008876.1\|126457_127789_+\|transposase	transposase	A0A1B0VCD8	Salmonella_phage	9.8e-86	45.6

DBSCAN-SWA_3

141232 : 170455

Salmonella_phage(33.33%)

transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_013007001.1\|141232_142444_+\|transposase	IS256 family transposase	A0A220NQR7	Corynebacterium_phage	2.8e-31	30.0
WP_041224027.1\|142411_142765_-	hypothetical protein	S4TSS7	Salmonella_phage	4.4e-09	41.1
WP_013008970.1\|142775_143183_-	hypothetical protein	NA	NA	NA	NA
WP_013008971.1\|143405_144065_+	hypothetical protein	NA	NA	NA	NA
WP_013008972.1\|144133_144811_+	hypothetical protein	NA	NA	NA	NA
WP_013008973.1\|144849_145221_+	hypothetical protein	NA	NA	NA	NA
WP_013008974.1\|145277_145670_+	hypothetical protein	NA	NA	NA	NA
WP_013008875.1\|145666_146092_-\|transposase	IS200/IS605 family transposase	A0A1S5RHE3	Helicobacter_phage	2.6e-48	67.9
WP_013008876.1\|146114_147446_+\|transposase	transposase	A0A1B0VCD8	Salmonella_phage	9.8e-86	45.6
WP_013008975.1\|147606_149055_+	RNA-splicing ligase RtcB	A0A2R2ZGS4	Clostridioides_phage	6.5e-67	36.2
WP_041224028.1\|149131_149323_+	hypothetical protein	NA	NA	NA	NA
WP_041224029.1\|149478_149724_+	hypothetical protein	NA	NA	NA	NA
WP_013008976.1\|149733_150411_+	hypothetical protein	NA	NA	NA	NA
WP_013008977.1\|150581_151607_+	hypothetical protein	A0A1V0SKG9	Klosneuvirus	5.7e-17	25.9
WP_013008978.1\|151627_152644_+	nucleotidyltransferase domain-containing protein	K0NVU0	Escherichia_virus	6.9e-15	25.8
WP_013008979.1\|152681_153035_+	hypothetical protein	NA	NA	NA	NA
WP_013008980.1\|153045_153630_+	hypothetical protein	NA	NA	NA	NA
WP_041224031.1\|153793_154132_+	hypothetical protein	NA	NA	NA	NA
WP_013008981.1\|154259_154502_-	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_013008982.1\|154512_155790_-	type II toxin-antitoxin system HipA family toxin	NA	NA	NA	NA
WP_013008983.1\|156134_156602_-	hypothetical protein	NA	NA	NA	NA
WP_153801544.1\|156641_156953_-	hypothetical protein	NA	NA	NA	NA
WP_013008985.1\|157016_157952_-	ankyrin repeat domain-containing protein	NA	NA	NA	NA
WP_013008986.1\|158014_158827_-	hypothetical protein	A0A1L7N1D2	Ralstonia_phage	2.5e-07	24.7
WP_013008987.1\|158846_159662_-	hypothetical protein	NA	NA	NA	NA
WP_013008988.1\|159944_161339_-	DNA double-strand break repair nuclease NurA	NA	NA	NA	NA
WP_050742542.1\|161400_162024_-	ATP-binding protein	NA	NA	NA	NA
WP_013008875.1\|162030_162456_-\|transposase	IS200/IS605 family transposase	A0A1S5RHE3	Helicobacter_phage	2.6e-48	67.9
WP_013008876.1\|162478_163810_+\|transposase	transposase	A0A1B0VCD8	Salmonella_phage	9.8e-86	45.6
WP_050742543.1\|163786_165199_-	DUF87 domain-containing protein	NA	NA	NA	NA
WP_013008989.1\|165203_166418_-	site-specific DNA-methyltransferase	NA	NA	NA	NA
WP_013008990.1\|166555_167356_-	hypothetical protein	NA	NA	NA	NA
WP_041224032.1\|167536_167851_-	hypothetical protein	NA	NA	NA	NA
WP_013008991.1\|167883_168348_-	chemotaxis protein CheX	NA	NA	NA	NA
WP_013008875.1\|168675_169101_-\|transposase	IS200/IS605 family transposase	A0A1S5RHE3	Helicobacter_phage	2.6e-48	67.9
WP_013008876.1\|169123_170455_+\|transposase	transposase	A0A1B0VCD8	Salmonella_phage	9.8e-86	45.6

DBSCAN-SWA_4

180073 : 228900

Helicobacter_phage(22.22%)

transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_013008875.1\|180073_180499_-\|transposase	IS200/IS605 family transposase	A0A1S5RHE3	Helicobacter_phage	2.6e-48	67.9
WP_013008876.1\|180521_181853_+\|transposase	transposase	A0A1B0VCD8	Salmonella_phage	9.8e-86	45.6
WP_041224035.1\|182037_183177_+	ATP-binding domain-containing protein	G5CQY8	Megavirus	2.3e-19	26.5
WP_013009003.1\|183546_184122_+	hypothetical protein	NA	NA	NA	NA
WP_013009004.1\|184259_187073_-	S8 family serine peptidase	A0A1B0T6A2	Bacillus_phage	3.9e-15	26.4
WP_013009005.1\|187265_188528_-	GGDEF domain-containing protein	G3MA91	Bacillus_virus	4.4e-19	33.1
WP_013009006.1\|188854_189409_+	hypothetical protein	NA	NA	NA	NA
WP_013009007.1\|189440_190280_-	hypothetical protein	NA	NA	NA	NA
WP_013009008.1\|190472_190826_+	hypothetical protein	NA	NA	NA	NA
WP_013009009.1\|190838_191810_+	hypothetical protein	NA	NA	NA	NA
WP_168902629.1\|191910_193515_-	Cache 3/Cache 2 fusion domain-containing protein	A0A2H4J162	uncultured_Caudovirales_phage	3.2e-14	49.5
WP_013009011.1\|193768_195496_-	Cache 3/Cache 2 fusion domain-containing protein	A0A2H4J162	uncultured_Caudovirales_phage	4.0e-07	91.2
WP_013008875.1\|195502_195928_-\|transposase	IS200/IS605 family transposase	A0A1S5RHE3	Helicobacter_phage	2.6e-48	67.9
WP_013008876.1\|195950_197282_+\|transposase	transposase	A0A1B0VCD8	Salmonella_phage	9.8e-86	45.6
WP_013009012.1\|197258_197723_-	hypothetical protein	NA	NA	NA	NA
WP_153801553.1\|197855_198086_-	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_013009014.1\|198422_198686_-	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_153801546.1\|198917_199529_-	hypothetical protein	NA	NA	NA	NA
WP_013009016.1\|199608_199941_-	STAS domain-containing protein	NA	NA	NA	NA
WP_013009017.1\|200004_200292_-	hypothetical protein	NA	NA	NA	NA
WP_013009018.1\|200327_201146_-	purine-binding chemotaxis protein CheW	NA	NA	NA	NA
WP_013009019.1\|201422_201854_+	hypothetical protein	NA	NA	NA	NA
WP_013009020.1\|201920_202817_+	chemotaxis protein CheW	Q56AR1	Bacillus_thuringiensis_phage	2.5e-29	29.4
WP_013009021.1\|202867_203248_+	response regulator	NA	NA	NA	NA
WP_013009022.1\|203446_205561_+	chemotaxis protein CheW	A0A1V0SGR9	Hokovirus	3.4e-08	34.2
WP_041224036.1\|205644_205926_-	hypothetical protein	NA	NA	NA	NA
WP_013009023.1\|205989_206397_-	DUF1232 domain-containing protein	NA	NA	NA	NA
WP_013009024.1\|206547_206799_-	hypothetical protein	NA	NA	NA	NA
WP_013009025.1\|206909_208094_-	GGDEF domain-containing protein	A0A127AWB9	Bacillus_phage	7.0e-19	35.2
WP_153801547.1\|208233_208746_+	hypothetical protein	NA	NA	NA	NA
WP_013008875.1\|208734_209160_-\|transposase	IS200/IS605 family transposase	A0A1S5RHE3	Helicobacter_phage	2.6e-48	67.9
WP_013008876.1\|209182_210514_+\|transposase	transposase	A0A1B0VCD8	Salmonella_phage	9.8e-86	45.6
WP_041224037.1\|210580_210919_+	hypothetical protein	NA	NA	NA	NA
WP_013009027.1\|210972_211962_-	hypothetical protein	NA	NA	NA	NA
WP_013009028.1\|212269_214201_+	DNA gyrase subunit B	G3M9Z3	Bacillus_virus	1.2e-137	44.5
WP_013009029.1\|214310_215762_+	hypothetical protein	NA	NA	NA	NA
WP_013009030.1\|215856_216804_+	hypothetical protein	NA	NA	NA	NA
WP_013009031.1\|216862_218206_-	toprim domain-containing protein	NA	NA	NA	NA
WP_013009032.1\|218516_220481_+	hypothetical protein	NA	NA	NA	NA
WP_013009033.1\|220576_223078_+	DNA topoisomerase 4 subunit A	A0A172JHV7	Bacillus_phage	4.2e-90	30.8
WP_013009034.1\|223169_224132_-	hypothetical protein	NA	NA	NA	NA
WP_013009035.1\|224226_225099_-	hypothetical protein	NA	NA	NA	NA
WP_013009036.1\|225136_226177_-	hypothetical protein	NA	NA	NA	NA
WP_013009037.1\|226292_227114_-	hypothetical protein	NA	NA	NA	NA
WP_013008875.1\|227120_227546_-\|transposase	IS200/IS605 family transposase	A0A1S5RHE3	Helicobacter_phage	2.6e-48	67.9
WP_013008876.1\|227568_228900_+\|transposase	transposase	A0A1B0VCD8	Salmonella_phage	9.8e-86	45.6

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. NC_013939

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection

2. NC_013940

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection