CRISPRimmunity

Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NC_004432	Mycoplasma penetrans HF-2, complete genome	4 crisprs	DEDDh	0	2	0	0

1. NC_004432

CRISPR-Cas detection and classification

Crispr_ID: NC_004432_1

• CRISPR_ID: NC_004432_1
• CRISPR_location: 664234-664325
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NC_004432_1

Consensus_repeat	Method
TTGGTTTTCCAATACTTTTTTCCTAAAAAT	CRISPRCasFinder

spacers of NC_004432_1

>1.1|664264|32|NC_004432|CRISPRCasFinder
TAATAAATTATATAAAAAATGGGAAAAAGTTA

CRISPR arrays and Neighbor proteins around NC_004432_1

CRISPR arrays

The CRISPR arrays of NC_004432_1

>merge|NC_004432|1|664234-664325|CRISPRCasFinder
TTGGTTTTCCAATACTTTTTTCCTAAAAATTAATAAATTATATAAAAAATGGGAAAAAGTTATTGGTTTTCCAATACTTTTTTCCTAAAAAT

>NC_004432|1|1|664234-664325|CRISPRCasFinder
TTGGTTTTCCAATACTTTTTTCCTAAAAAT	TAATAAATTATATAAAAAATGGGAAAAAGTTA
TTGGTTTTCCAATACTTTTTTCCTAAAAAT

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_004432.1|WP_011077342.1|659569_660043_-|23S-rRNA-(pseudouridine(1915)-N(3))-methyltransferase-RlmH	unknown	unknown	gnl|CDD|376840
NC_004432.1|WP_011077349.1|666499_666865_-|hypothetical-protein	unknown	unknown	unknown
NC_004432.1|WP_011077345.1|662085_662772_+|5'-methylthioadenosine/S-adenosylhomocysteine-nucleosidase	unknown	unknown	gnl|CDD|350159
NC_004432.1|WP_011077340.1|656177_657749_+|MFS-transporter	unknown	unknown	gnl|CDD|284977
NC_004432.1|WP_011077355.1|674657_675275_-|UPF0236-family-protein	unknown	unknown	gnl|CDD|284250
NC_004432.1|WP_011077337.1|653077_654109_-|aldo/keto-reductase	unknown	unknown	gnl|CDD|381305
NC_004432.1|WP_152023093.1|669427_671554_-|RelA/SpoT-family-protein	unknown	unknown	gnl|CDD|213552
NC_004432.1|WP_011077354.1|673822_674575_+|hypothetical-protein	unknown	unknown	unknown
NC_004432.1|WP_044891260.1|654906_655995_+|hypothetical-protein	unknown	unknown	unknown
NC_004432.1|WP_052270423.1|654227_654773_-|TetR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|274100
NC_004432.1|WP_011077351.1|668556_669318_-|hypothetical-protein	unknown	unknown	unknown
NC_004432.1|WP_044891261.1|664672_665731_+|NAD(P)-dependent-alcohol-dehydrogenase	unknown	unknown	gnl|CDD|176186
NC_004432.1|WP_011077346.1|662833_664165_-|ATP-binding-protein	unknown	unknown	gnl|CDD|224292
NC_004432.1|WP_011077348.1|665787_666390_-|RdgB/HAM1-family-non-canonical-purine-NTP-pyrophosphatase	unknown	unknown	gnl|CDD|238285
NC_004432.1|WP_011077344.1|661024_662074_+|nicotinate-nucleotide-adenylyltransferase	unknown	unknown	gnl|CDD|235947
NC_004432.1|WP_044891263.1|675316_676063_+|hypothetical-protein	unknown	unknown	unknown
NC_004432.1|WP_011077343.1|660051_660870_-|Cof-type-HAD-IIB-family-hydrolase	unknown	unknown	gnl|CDD|369792
NC_004432.1|WP_011077353.1|671799_673689_+|ribonuclease-J	unknown	unknown	gnl|CDD|223668
NC_004432.1|WP_011077341.1|657866_659516_+|APC-family-permease	unknown	unknown	gnl|CDD|372624
NC_004432.1|WP_011077350.1|666987_668361_-|ATP-binding-protein	unknown	unknown	gnl|CDD|224586

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_004432.1|WP_011077342.1|659569_660043_-|23S-rRNA-(pseudouridine(1915)-N(3))-methyltransferase-RlmH	gnl|CDD|376840	pfam02590, SPOUT_MTase, Predicted SPOUT methyltransferase. This family of proteins are predicted to be SPOUT methyltransferases.	3.34145e-62
NC_004432.1|WP_011077345.1|662085_662772_+|5'-methylthioadenosine/S-adenosylhomocysteine-nucleosidase	gnl|CDD|350159	cd09008, MTAN, 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidases. This subfamily includes both bacterial and plant 5'-methylthioadenosine/S-adenosylhomocysteine (MTA/SAH) nucleosidases (MTANs): bacterial MTANs show comparable efficiency in hydrolyzing MTA and SAH, while plant enzymes are highly specific for MTA and are unable to metabolize SAH or show significantly reduced activity towards SAH. MTAN is involved in methionine and S-adenosyl-methionine recycling, polyamine biosynthesis, and bacterial quorum sensing. This subfamily belongs to the nucleoside phosphorylase-I (NP-I) family, whose members accept a range of purine nucleosides as well as the pyrimidine nucleoside uridine. The NP-1 family includes phosphorolytic nucleosidases, such as purine nucleoside phosphorylase (PNPs, EC. 2.4.2.1), uridine phosphorylase (UP, EC 2.4.2.3), and 5'-deoxy-5'-methylthioadenosine phosphorylase (MTAP, EC 2.4.2.28), and hydrolytic nucleosidases, such as AMP nucleosidase (AMN, EC 3.2.2.4), and 5'-methylthioadenosine/S-adenosylhomocysteine (MTA/SAH) nucleosidase (MTAN, EC 3.2.2.16). The NP-I family is distinct from nucleoside phosphorylase-II, which belongs to a different structural family.	1.53403e-47
NC_004432.1|WP_011077340.1|656177_657749_+|MFS-transporter	gnl|CDD|284977	pfam07672, MFS_Mycoplasma, Mycoplasma MFS transporter. These proteins share some similarity with members of the Major Facilitator Superfamily (MFS).	1.24785e-93
NC_004432.1|WP_011077355.1|674657_675275_-|UPF0236-family-protein	gnl|CDD|284250	pfam06782, UPF0236, Uncharacterized protein family (UPF0236).	0.00214066
NC_004432.1|WP_152023093.1|669427_671554_-|RelA/SpoT-family-protein	gnl|CDD|213552	TIGR00691, PppGpp_synthetase., (p)ppGpp synthetase, RelA/SpoT family. The functions of E. coli RelA and SpoT differ somewhat. RelA (EC 2.7.6.5) produces pppGpp (or ppGpp) from ATP and GTP (or GDP). SpoT (EC 3.1.7.2) degrades ppGpp, but may also act as a secondary ppGpp synthetase. The two proteins are strongly similar. In many species, a single homolog to SpoT and RelA appears reponsible for both ppGpp synthesis and ppGpp degradation. (p)ppGpp is a regulatory metabolite of the stringent response, but appears also to be involved in antibiotic biosynthesis in some species. [Cellular processes, Adaptations to atypical conditions].	1.22085e-138
NC_004432.1|WP_011077337.1|653077_654109_-|aldo/keto-reductase	gnl|CDD|381305	cd19079, AKR_EcYajO-like, Escherichia coli YajO and similar proteins. Escherichia coli YajO is the prototype of this family. It is an uncharacterized aldo/keto reductase family oxidoreductase.	8.93102e-179
NC_004432.1|WP_052270423.1|654227_654773_-|TetR-family-transcriptional-regulator	gnl|CDD|274100	TIGR02366, conserved_hypothetical_protein, probable dihydroxyacetone kinase regulator. The seed alignment for this family was built from a set of closely related uncharacterized proteins associated with operons for the type of bacterial dihydroxyacetone kinase that transfers PEP-derived phosphate from a phosphoprotein, as in phosphotransferase system transport, rather than from ATP. Members have a TetR transcriptional regulator domain (pfam00440) at the N-terminus and sequence homology throughout.	1.05074e-06
NC_004432.1|WP_044891261.1|664672_665731_+|NAD(P)-dependent-alcohol-dehydrogenase	gnl|CDD|176186	cd05283, CAD1, Cinnamyl alcohol dehydrogenases (CAD). Cinnamyl alcohol dehydrogenases (CAD), members of the medium chain dehydrogenase/reductase family, reduce cinnamaldehydes to cinnamyl alcohols in the last step of monolignal metabolism in plant cells walls. CAD binds 2 zinc ions and is NADPH- dependent. CAD family members are also found in non-plant species, e.g. in yeast where they have an aldehyde reductase activity. The medium chain dehydrogenases/reductase (MDR)/zinc-dependent alcohol dehydrogenase-like family, which contains the zinc-dependent alcohol dehydrogenase (ADH-Zn) and related proteins, is a diverse group of proteins related to the first identified member, class I mammalian ADH. MDRs display a broad range of activities and are distinguished from the smaller short chain dehydrogenases (~ 250 amino acids vs. the ~ 350 amino acids of the MDR). The MDR proteins have 2 domains: a C-terminal NAD(P) binding-Rossmann fold domain of a beta-alpha form and an N-terminal catalytic domain with distant homology to GroES. The MDR group contains a host of activities, including the founding alcohol dehydrogenase (ADH), quinone reductase, sorbitol dehydrogenase, formaldehyde dehydrogenase, butanediol DH, ketose reductase, cinnamyl reductase, and numerous others. The zinc-dependent alcohol dehydrogenases (ADHs) catalyze the NAD(P)(H)-dependent interconversion of alcohols to aldehydes or ketones. Active site zinc has a catalytic role, while structural zinc aids in stability. ADH-like proteins typically form dimers (typically higher plants, mammals) or tetramers (yeast, bacteria), and generally have 2 tightly bound zinc atoms per subunit. The active site zinc is coordinated by a histidine, two cysteines, and a water molecule. The second zinc seems to play a structural role, affects subunit interactions, and is typically coordinated by 4 cysteines.	1.39675e-169
NC_004432.1|WP_011077346.1|662833_664165_-|ATP-binding-protein	gnl|CDD|224292	COG1373, COG1373, Predicted ATPase (AAA+ superfamily) [General function prediction only].	9.86142e-51
NC_004432.1|WP_011077348.1|665787_666390_-|RdgB/HAM1-family-non-canonical-purine-NTP-pyrophosphatase	gnl|CDD|238285	cd00515, HAM1, NTPase/HAM1. This family consists of the HAM1 protein and pyrophosphate-releasing xanthosine/ inosine triphosphatase. HAM1 protects the cell against mutagenesis by the base analog 6-N-hydroxylaminopurine (HAP) in E. Coli and S. cerevisiae. A Ham1-related protein from Methanococcus jannaschii is a novel NTPase that has been shown to hydrolyze nonstandard nucleotides such as XTP to XMP and ITP to IMP, but not the standard nucleotides, in the presence of Mg or Mn ions. The enzyme exists as a homodimer. The HAM1 protein may be acting as an NTPase by hydrolyzing the HAP triphosphate.	5.68807e-69
NC_004432.1|WP_011077344.1|661024_662074_+|nicotinate-nucleotide-adenylyltransferase	gnl|CDD|235947	PRK07152, nadD, nicotinate-nucleotide adenylyltransferase.	3.25474e-134
NC_004432.1|WP_011077343.1|660051_660870_-|Cof-type-HAD-IIB-family-hydrolase	gnl|CDD|369792	pfam08282, Hydrolase_3, haloacid dehalogenase-like hydrolase. This family contains haloacid dehalogenase-like hydrolase enzymes.	5.63933e-64
NC_004432.1|WP_011077353.1|671799_673689_+|ribonuclease-J	gnl|CDD|223668	COG0595, COG0595, mRNA degradation ribonucleases J1/J2 (metallo-beta-lactamase superfamily) [Translation, ribosomal structure and biogenesis; Replication, recombination and repair].	0
NC_004432.1|WP_011077341.1|657866_659516_+|APC-family-permease	gnl|CDD|372624	pfam13520, AA_permease_2, Amino acid permease.	5.73105e-36
NC_004432.1|WP_011077350.1|666987_668361_-|ATP-binding-protein	gnl|CDD|224586	COG1672, COG1672, Predicted ATPase (AAA+ superfamily) [General function prediction only].	2.18426e-12

Protein sequences

>NC_004432.1|WP_011077346.1|662833_664165_-|ATP-binding-protein
MEIKRDSYLKQLVSSIDNNLIKVITGIRRCGKSYLLNNIFKNYLISKGINEDQIIIIQLDKKVNEHLRSPDKLMDFLLEVLPKDKKTFLFIDEIQLCLSVNKYLKVKDTDQKVKIESNFYSILNQILYDYPNVNVYVTGSNSKMLSKDVLTEFRGRSWEIKVFPLSFSEFYNSYKELKDDDKNKAWNEYLLYGGMPNILNIESEIDKTKYLKDLFKLTYLKDIVEKNKLENDIVIENLLKILSSTMGSLTNTLNLTNTFKSEFDKTISWKILDKYINCFTDSFLINKSIRYDISGKKYAKNLYKYYFIDTGLRNACLDFRQLDRGFLMETIIYNELTRRGYSVDIGYLPIWEKNKDNKNIKKNLEVDFVANLASKRYYIQSTYNMNNYEKEVSESKGLLKIKDTFTKIIIEYESITNYYDENGVLHIGLLDFLLEPNILEKTI
>NC_004432.1|WP_011077345.1|662085_662772_+|5'-methylthioadenosine/S-adenosylhomocysteine-nucleosidase
MIGFIIALEEEITSIKDIDKNIKVYQTDFFKYYLFSKNNIDFVLVFSGVGKANAAACCLEIIKTFSLTKLINIGVCGVNKKDIKTDDVLLLSRNYYLDVDATEFGYKYGQVPKEKEYFENNNKLNSDIKSIFEVNEINYKECYGGTSDSFITLMNIDKLNKEVFNIVSAIDMEATAINQIASKTKIDTAFIKIVSDNILEEKNKYTENQISWPKTVTNIINLITNNIK
>NC_004432.1|WP_011077344.1|661024_662074_+|nicotinate-nucleotide-adenylyltransferase
MKKIIIFGGTFDPIHKGHIEIAKKAIKKVKADRLFFVPCNQHPDSKDISASKQERLDMINLSIQNMPEFEICEFELNNDQPSFTINTIRYFKEQYSNCLIYLLIGYDQLINFKTWHNYQEILDYVNIISHVRKVNKEELEKVDFPFIKIGNKNIDAASRELKINPNRKYLNDKVINYINENCVYAYDRLKLVMSEYRLNHCIETANIAKEIALKHKLYPLVKKAYVAGYYHDYAKEFDKDKQIKIAKKLKIKKYPSWKVLHGPVATYYMEKYFLIDDYQIITAIKNHTVPQDFSTLTKIIFIADKIAPRDDEAKKIRKDWTKTAFKDIDKCFKDIIDFYEGFYQNNIVK
>NC_004432.1|WP_011077343.1|660051_660870_-|Cof-type-HAD-IIB-family-hydrolase
MFSNVKYAYFDLDGTLIPNNKTISEETIKAFQHLQSKGVKVGIATGRSPYFVVPYQDRIKTNLPFICINGSFVVDEKKNVLLERPFPKSANILFDYLVSHQIDFLVYAQEGVYFSDIKHMYYEKLSNMAKTIGFEIDFDFKEVKDLEFFKNKKFLKILVSFKDENDKKKIEELVNKVDGITCASSQANVMDIFNSEADKAYGIEFVVKSFNGNNDEVIVFGDNENDIKMFQTFKNSVALKNAKPEVSKHAKFVTDLTCSENGVADFIFKNFK
>NC_004432.1|WP_011077342.1|659569_660043_-|23S-rRNA-(pseudouridine(1915)-N(3))-methyltransferase-RlmH
MKIKIICFGKIKDKNITALINEYLSKINHFTNLTIVELSEEKINNENSIGEIEEALKKESKKLIPYLENSFNVLLDIKGVQMDSIKFANSINQNLIISKDINFYIGSSHGISESIKNKFNLKLSFSELTFNHQIFRLILLEQIYRAFSILNNTKYHK
>NC_004432.1|WP_011077341.1|657866_659516_+|APC-family-permease
MNSNRSENSYSIDFNEVKQSVNVGKKKISFISAILIVIGSCIGSGIFLKSSSILSNTWYSLPLSITTWVVSAIAVIAMSLALIEITSVKSNNLGMIGWVKNFNKKFVYKACKNFMFFIYTPLSFFFMPLYVLNSFQDALTAFGASNNFGTSVDFLIWSFIAILISAWFIFSSGLNAKTGNIQNWIITSIKFFPIVIIIVLGFYIAIANNIGNDIVVTPDSSQKDPTSFAGISPVVGMFISFGAIFFAYDGFYFSNGVMTEMETPKKASFALIIGLSITTIIYLLIAIAMTFSNPKSGSLNDFSKFLQTKNASWVFGIVNLMVSIGICGIINGLSMWATRFAEDLIKSGELVLFYKYSNKLNPHRPIVGSIYTAIIALIMFVIFALIGGLAYTPGGYVDGYDAAGYNSMAKLLNFADLMGNWTSILVFAFIVAAIFSCLMNRKTNRIKVVKYKYFVPVAITSILIVGFGTAIQFASPFIDVIMMAVPSIRAQLTQEDIIGRIMLIVVLVVFIIAMIVPSVFDYDSKFLQTKFKFNVFKNEDGLDQVDLIG
>NC_004432.1|WP_011077340.1|656177_657749_+|MFS-transporter
MKNLSFGFKNKDTKSINQKTLTLMWSLMFLGYLLFVLQWYSIINFGSGWGQAFFENNRQSILVSSVPNWMITFGRSIGSILAGYFIAKLGHKYAVVFCLTLMVVSFPFIIIAQNQSWNSLSIAGGASITHDGVYETAVLGFSLFVIFRVFLAIGGTTLIVYTNSVIAKMNQNKKSKYIASNTFGLNIGAILANVFFIIPEVRSAVTNNYVWTIVLSIPIILISLISIIYLLFGIEVVAKDNKSQTEFTDNKKHTIKSVLKIKENYSLYCIFGIYLFSLVFSTGSGFRNFIEQSPANVAYLISVNQTSIASGYYAFVWPLFICVLMFSYVASAFTLTKFNKTSFNRKTYIATLLGTGMLFLLIAYLVVYFFGYSNYFALFFFYIFTFIAGAFLWGAQPIIFYIPQQQKQADANYVGTTAGLAWGIGYLLYTLLDASLSSIATYVVEEQFSNKINNALSNPNYSYSINTGPVIMFVLFWIILLFFFVCIYFLPSTGYKKDNQFIEFKNKWNPLNINHWKFKNFYI
>NC_004432.1|WP_044891260.1|654906_655995_+|hypothetical-protein
MKKAFIVKSEQGYKKLNLTKTIQLWEDGLRTTGKRGEYEWWYYDAKMDDGSTLVITFFTTNPTNTKGGFNPNIKIEFTRRDGSKVSDLIYVDKKDCYFNKNKCEVKMKDNFFIGDLNKYYIYVRSPKIEANIELSANVKSWRPETGFQQFGEKEYFAWLPSVPEGKTKATIRIDNSIEEFLGTGYHDHNWGNTSMLKLLHHWYWGRAKVGPYTVISCFLTTVKKYGYTKFPIFMIANEDKLICDDANNINFYTEEKQLSNTTGKWYDNKLVYDYNGVEGHYKITYVVKEIISSFSLLEDEGKKPQKFKRTLVNIFGLDPTYDRFNGEVIFEKIENNVVVEKHVNNATWELMHFRKDKKNKQV
>NC_004432.1|WP_052270423.1|654227_654773_-|TetR-family-transcriptional-regulator
MYEGNNVSAKASMNFLADALMNLLIKEKYINITISDLCEYAKLSRQTFYNVFESKSEILHYCLKREYEKQFKELSLNNEISIKDIINLFISFWNDNKQLLDNLINNQLEEIIVEEIRNCICLYTNHFVKKSNSKLQPYSTAMLAGALSQLQFVIFKNKNELSQQEIEALLIDFFNGNLYTL
>NC_004432.1|WP_011077337.1|653077_654109_-|aldo/keto-reductase
MEYIKLGNSDLKVSRICLGCMGFGDNKSGVHKWILDYQQTKEIIKLALDKGINFFDTAPVYAEGTSEEFLGRAIQELTKRENVVIATKFFPRSREAYEKGITGQQWVQQNLEQSLKRLNTDYVDLYILHLWDYNTPIEDILEGLNNAVKSKKVRAIGISNCYAWQLQKANDIAKANGWSQFVSIQGHYNLIFREEEREMIPFCEENNVALTPYSVLASGRLVKESNETSARLESDYIAKLKYDSSKEVDEIIINRVKELAKKKGLSNTQIALGWLLNKGVHSPIIGATKIKHIEEAVSAVGIKLSEEEIAYLSDPYVPHKLVGVMGNNKKGQFFDMTLKNNKK
>NC_004432.1|WP_044891261.1|664672_665731_+|NAD(P)-dependent-alcohol-dehydrogenase
MIDITKRITTKGKALFSKDGKIEDFTFERRALNDDDILIKIKYCGICHSDIHHGRSEWGKANYPTVMGHEIVGEVVATGNKVSKFKVGDNAGIGCMVNSCGNCDSCKVSEEQYCNDMVVTYGGLDKFNNNEMTYGGYSNYYVVKESFAIKVPQNVPLEYIAPLFCAGITTYSPIVFSKVKKGDKVAIAGFGGLGVMAVKYAKFLGADVYVIARNNKKEEEAKKLGVKKLYPSVESVDEKFDLIISTIPTKYEVMDYVNLLKVGGELALLGLPPVEEGWSLYPGNLIFKGHRKVYGSIIGGIKATQEMLDFSIKHNIYPEIEVISADQINEAFEKMTTGKAKFRYVIDMSTLK
>NC_004432.1|WP_011077348.1|665787_666390_-|RdgB/HAM1-family-non-canonical-purine-NTP-pyrophosphatase
MKIILATQNKRKLDEFIELSKNSNYPINFVIKPLKEDIGEIEENGNSYFENALIKANAVFNYYKEPVLSDDSGLELPEFKEILGIYSSRFAGINATDKENRYKLLDYLKSKNITETSAKYVCVLVYIFNQGEALSFKGEWEGKIIVSDNLNLDTGFGYDPMFVPKEYTITVSEMSISEKNLISHRAKAVNQFLNFLKDKK
>NC_004432.1|WP_011077349.1|666499_666865_-|hypothetical-protein
MIKKLKNKKLNKSPVLKETFSNRQESIVWENNTNRSLQQWDETKESQKEKEMKNNLEIELRKREEQVKIEKQKVFLSEIKKESLKEEESFSKRAEIDEKIRNKKRKEIKKRDIEYRNRNYG
>NC_004432.1|WP_011077350.1|666987_668361_-|ATP-binding-protein
MFFGRKKELDRISEKINSNKFENILLTGIKRIGKTSLLKKVSDNFEGYKIFFAATESGYDNNFKNLWNMVSKLFDVKFNLNDPNDILGFIFEKSLEHKILFIIDEYPYLKSNLKKLDSILQILIDHNHEKSKMKLIISGSYIKAMNNIISYSNPLYGRFTDRIVLKDLNYLEVSNFYPNYSLEDKVKMYSIFGGNPFYNSFIDNNISVNENIKRNILNNPFCLDSPIKIYGEEINNIEGANMVFNSIATGKHRYKDLVSGAVSLQNLPYVLEPLLEMGLINKQTPINMRDNKRKTLYYIEDNFIDFYYKYIFNNFNNFINMNTDDFFEEMIRNELETYTIPKKFEKLSREAILHMNLNKLNNINYKDIGKYWYDDPKTKTNMEFDVVCKDKEDSYVFFEVKFSKNPIGDNVVNKKIYQLNQLKINNYKLGFISKSGFDLSHKKDYILFDLKDLYLER
>NC_004432.1|WP_011077351.1|668556_669318_-|hypothetical-protein
MKMKNFNYDLKTKINYYQYLWLILVFCFLSFSLVIATIAVSIATNDFIAYAVLKGLASLAFLVIGIYSITKLKTAQRLKWKHFINLGFIFVSFVANILMNINLIASISTFLAAQCIYILYCNYNYKFTSKKELWLLTTYIPIIVLVNVLFGVGVFNRNAAYWTISNFYGIAIVTSIVYAIITYHRNQNMISLLTIITLLLLFVSSLLFMFKTFMITSYINNEADKTLTFFTLLTYFLSMNMNSLNLKNINFNY
>NC_004432.1|WP_152023093.1|669427_671554_-|RelA/SpoT-family-protein
MTTTNIKKRFLFLTGLLKQNNFSADQIKLVKKAFEFANLKHGSQIRKSGEPYMIHPLETAIYLAEWKMDVSTIITGLLHDVLEDTDCTREDMEKRFGKTILEMVETVTKVSKVSQETRSKETYDKENSEYIIRVIMSVSSNLRSVIVKIADRMHNMETINHLKKEKQIRIASETFNIYANIAGRLGLYHQKTRLLDLSFQVLEPEKYESIKNMIDTSLKNCRESLNNVSQQIKDILTSKGIDFTVVERIKGIYSTYKKIEKGIDIKNIHDLFALRIITNREDIECYRILGLIHINFTFLPQTFKDYISSPKLNLYQSLHTTITFRKVLLEIQIRNSAMDKTANFGVAAHWLYKQNEEDIKEVTSELMFDILNNSDKEISKKIKNIQLTKIYDVLLLNNNKWYVVNEGSTVLDLACRYKPEKIFYLKTVFKEGVPVDLNYNPIKDDVLSFEYNDGHEVLAHHSWEEYVTFEDAKKIFRSLATDNDEPNKLVRELKNALKDKLESAKEIKRRLAFLNFNTLESYLEFYKNFSNKEIVYGFLSKTRKWKKYYLELSKGISKYELLLYNIKDKNIFNCKKAIFTECCTKLPGMDIIGVLNKGVLFIHRFDCERVSDKSKKFILEWDLDKATELTRSYPATLIININSKIFKINPIIHFITSKGFEIDSFDSSLKEDNKVLTFKLQVNKINNLNLLITELTYKFEQISSVKFK
>NC_004432.1|WP_011077353.1|671799_673689_+|ribonuclease-J
MKNNNDNKNKFFNNKKNFNKKPNQNNSLNENDLENESKDEKKLIDIKQIPEEDRVDYSRFKNIPISNEFKNKPDHTYVFAVGGLDEVGKNSYAIEHNEETIMVDYGIKFASSDLLGINGIVANTSYFVENNRPIDALLLTHGHEDHIGGIPYLLQTTEVKKIYAPLLATELIKRRLSEFRDIKYNPEIIPFGDDSKVSTKYFEVDFFRVCHSIPDSFGMCIKTPNGRIVSAGDYRYDFGKDTDDTNIHKLVEMSNRGIDIFLSESTNSDQPGFSPSEDNIINNIETLIKNSKGRVFVATFASNLGRIEKIIERAIKSGRRVCIMGRSMEANIKTSKKLGYLKISESDFLTTKELNECKDREILVVLTGSQGEEMAALNQMALGKHPRLSLKPSDSIIMSSNPIPGNFKSVELLINRLYKQGVNMYTNSPNFRIHSSGHATIQELQMMFKILKPKYLIPIHGESKMLSAMKRNANSIGINPENVFVLTNGLKVELKDHNLKLTNQRIDACPIYIDKKVASKSTTDLINKRKLLSEEGIFNIIVLIDHKNKKVVKNPMLSTRGCFYAKDSSSLITKISFSVKDEIESLLNKEAEASKEKIKQAVANVVKFYVWKNKKKNPIVTTTVFDINK
>NC_004432.1|WP_011077354.1|673822_674575_+|hypothetical-protein
MLLKKLLLIGGGVVVGSTALASAIAIPISQSQLNSSSAEVPTDPNGNNQPNDQNGNNSQNGENNNNQNPDNNGNGGENINPAPDANEDNNLIKDVKLPEGGVVFRNFGDGFIQKEESFAYQVYSKGISSENDLNNKLNEWFNQNKDKDNFNGTHFFSVKDISFLSHFSNESYNYEVITYVNNSAKIIKTVDSSNNQDSQNSDSSILKNKVYSLEVTLKPASGHAWTDGTSQSKTITVYGVYSGVSNKSDK
>NC_004432.1|WP_011077355.1|674657_675275_-|UPF0236-family-protein
MNIDNHYINKSNLDYLDFSKKAESLIKKPNYFENSVEDERILNLRKCEEIANQLKELDESLFLNRKELTKKYNTKVYVWNKESRIIITPFGEVKFQRRSYFYIDQYNKKIWFYLLDDYINLEKYKRFDTNYKNRIFNKIKNDKVYSLEQLSKVNYRNCCKATVHNFLKGKVLNEEFDNQEKLVLDPSKNLYVNIDDTYVYFKNKD
>NC_004432.1|WP_044891263.1|675316_676063_+|hypothetical-protein
MKIKKAIKYLIPLSLTAVVVPISTASCSLYNSFSSNNGSSGNNDNNSTDGNNTTTTDPSQENYYKCTTNYKTVMTTLSTGELFANSPKILNYFYNELNNVQLLDEFGVIINLYDKVEDAANKDGYENSDLAGAYRIFCAAYLQYYDFSLSYVLGLKQIWKNEKIYSDDNPNEYSDEKKAILKQLNDSLNTYNNKNVRNIKSLLEFQIRYQNYIDEQEKTQELRKMFGYFNEANAFFGSVSSLYIKLNN

Crispr_ID: NC_004432_2

• CRISPR_ID: NC_004432_2
• CRISPR_location: 721167-721261
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NC_004432_2

Consensus_repeat	Method
TTAACTTCAACCATGTCAGTTTTTAGTTGAGC	CRISPRCasFinder

spacers of NC_004432_2

>2.1|721199|31|NC_004432|CRISPRCasFinder
AACATCTGTTTTTAATTCAACAATGTCTTTC

CRISPR arrays and Neighbor proteins around NC_004432_2

CRISPR arrays

The CRISPR arrays of NC_004432_2

>merge|NC_004432|2|721167-721261|CRISPRCasFinder
TTAACTTCAACCATGTCAGTTTTTAGTTGAGCAACATCTGTTTTTAATTCAACAATGTCTTTCTTCATTTCAACAATGTCTGCCTTAACTTGAAC

>NC_004432|2|2|721167-721261|CRISPRCasFinder
TTAACTTCAACCATGTCAGTTTTTAGTTGAGC	AACATCTGTTTTTAATTCAACAATGTCTTTC
TTCATTTCAACAATGTCTGCCTTAACTTGAAC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_004432.1|WP_044891382.1|716097_716577_+|peptide-methionine-(S)-S-oxide-reductase-MsrA	unknown	unknown	gnl|CDD|237597
NC_004432.1|WP_011077401.1|732759_733620_-|hypothetical-protein	unknown	unknown	unknown
NC_004432.1|WP_044891270.1|730910_731348_-|TM2-domain-containing-protein	unknown	unknown	gnl|CDD|377473
NC_004432.1|WP_011077388.1|719196_719757_+|peptide-deformylase	unknown	unknown	gnl|CDD|234668
NC_004432.1|WP_011077390.1|721636_722152_-|hypothetical-protein	unknown	unknown	unknown
NC_004432.1|WP_011077381.1|710796_713286_-|DEAD/DEAH-box-helicase-family-protein	unknown	unknown	gnl|CDD|214947
NC_004432.1|WP_011077386.1|717468_718527_-|23S-rRNA-(adenine(2503)-C(2))-methyltransferase-RlmN	unknown	unknown	gnl|CDD|237717
NC_004432.1|WP_011077392.1|722713_723904_-|acetate-kinase	unknown	unknown	gnl|CDD|234680
NC_004432.1|WP_011077383.1|714797_715439_-|hypothetical-protein	unknown	unknown	unknown
NC_004432.1|WP_129374455.1|729421_730894_-|MFS-transporter	unknown	unknown	gnl|CDD|349949
NC_004432.1|WP_044891271.1|731732_732668_-|hypothetical-protein	unknown	unknown	unknown
NC_004432.1|WP_052270425.1|713278_714808_-|Eco57I-restriction-modification-methylase-domain-containing-protein	unknown	unknown	gnl|CDD|369456
NC_004432.1|WP_011077397.1|728691_729429_-|glycerophosphodiester-phosphodiesterase	unknown	unknown	gnl|CDD|176506
NC_004432.1|WP_011077395.1|727526_727892_-|50S-ribosomal-protein-L7/L12	unknown	unknown	gnl|CDD|234671
NC_004432.1|WP_011077358.1|719923_720940_+|IS30-family-transposase	unknown	unknown	gnl|CDD|225382
NC_004432.1|WP_011077385.1|716684_717482_-|serine/threonine-protein-phosphatase	unknown	unknown	gnl|CDD|223704
NC_004432.1|WP_044891269.1|727919_728405_-|50S-ribosomal-protein-L10	unknown	unknown	gnl|CDD|240223
NC_004432.1|WP_052270424.1|709424_710609_-|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl|CDD|224059
NC_004432.1|WP_011077387.1|718526_719117_-|guanylate-kinase	unknown	unknown	gnl|CDD|213788
NC_004432.1|WP_011076843.1|724146_725703_+|DDE-type-integrase/transposase/recombinase	unknown	unknown	gnl|CDD|366234

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_004432.1|WP_044891382.1|716097_716577_+|peptide-methionine-(S)-S-oxide-reductase-MsrA	gnl|CDD|237597	PRK14054, PRK14054, peptide-methionine (S)-S-oxide reductase.	6.70344e-83
NC_004432.1|WP_044891270.1|730910_731348_-|TM2-domain-containing-protein	gnl|CDD|377473	pfam05154, TM2, TM2 domain. This family is composed of a pair of transmembrane alpha helices connected by a short linker. The function of this domain is unknown, however it occurs in a wide range or protein contexts.	5.27559e-10
NC_004432.1|WP_011077388.1|719196_719757_+|peptide-deformylase	gnl|CDD|234668	PRK00150, def, peptide deformylase; Reviewed.	4.74865e-47
NC_004432.1|WP_011077386.1|717468_718527_-|23S-rRNA-(adenine(2503)-C(2))-methyltransferase-RlmN	gnl|CDD|237717	PRK14455, PRK14455, ribosomal RNA large subunit methyltransferase N; Provisional.	3.53734e-159
NC_004432.1|WP_011077381.1|710796_713286_-|DEAD/DEAH-box-helicase-family-protein	gnl|CDD|214947	smart00974, T5orf172, This entry represents the putative helicase A859L.	1.42589e-09
NC_004432.1|WP_011077392.1|722713_723904_-|acetate-kinase	gnl|CDD|234680	PRK00180, PRK00180, acetate kinase A/propionate kinase 2; Reviewed.	0
NC_004432.1|WP_129374455.1|729421_730894_-|MFS-transporter	gnl|CDD|349949	cd06174, MFS, Major Facilitator Superfamily. The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of substrates including ions, sugar phosphates, drugs, neurotransmitters, nucleosides, amino acids, and peptides. They do so using the electrochemical potential of the transported substrates. Uniporters transport a single substrate, while symporters and antiporters transport two substrates in the same or in opposite directions, respectively, across membranes. MFS proteins are typically 400 to 600 amino acids in length, and the majority contain 12 transmembrane alpha helices (TMs) connected by hydrophilic loops. The N- and C-terminal halves of these proteins display weak similarity and may be the result of a gene duplication/fusion event. Based on kinetic studies and the structures of a few bacterial superfamily members, GlpT (glycerol-3-phosphate transporter), LacY (lactose permease), and EmrD (multidrug transporter), MFS proteins are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement. Bacterial members function primarily for nutrient uptake, and as drug-efflux pumps to confer antibiotic resistance. Some MFS proteins have medical significance in humans such as the glucose transporter Glut4, which is impaired in type II diabetes, and glucose-6-phosphate transporter (G6PT), which causes glycogen storage disease when mutated.	9.43492e-10
NC_004432.1|WP_052270425.1|713278_714808_-|Eco57I-restriction-modification-methylase-domain-containing-protein	gnl|CDD|369456	pfam07669, Eco57I, Eco57I restriction-modification methylase. homologs of the Escherichia coli Eco57I restriction-modification methylase are found in several phylogenetically diverse bacteria. The structure of TaqI has been solved.	1.05745e-48
NC_004432.1|WP_011077397.1|728691_729429_-|glycerophosphodiester-phosphodiesterase	gnl|CDD|176506	cd08563, GDPD_TtGDE_like, Glycerophosphodiester phosphodiesterase domain of Thermoanaerobacter tengcongensis and similar proteins. This subfamily corresponds to the glycerophosphodiester phosphodiesterase domain (GDPD) present in Thermoanaerobacter tengcongensis glycerophosphodiester phosphodiesterase (TtGDE, EC 3.1.4.46) and its uncharacterized homologs. Members in this family show high sequence similarity to Escherichia coli GP-GDE, which catalyzes the degradation of glycerophosphodiesters to produce sn-glycerol-3-phosphate (G3P) and the corresponding alcohols. Despite the fact that most of GDPD family members exist as the monomer, TtGDE can function as a dimeric unit. Its catalytic mechanism is based on the general base-acid catalysis, which is similar to that of phosphoinositide-specific phospholipases C (PI-PLCs, EC 3.1.4.11). A divalent metal cation is required for the enzyme activity of TtGDE.	8.86005e-95
NC_004432.1|WP_011077395.1|727526_727892_-|50S-ribosomal-protein-L7/L12	gnl|CDD|234671	PRK00157, rplL, 50S ribosomal protein L7/L12; Reviewed.	2.40369e-41
NC_004432.1|WP_011077358.1|719923_720940_+|IS30-family-transposase	gnl|CDD|225382	COG2826, Tra8, Transposase and inactivated derivatives, IS30 family [DNA replication, recombination, and repair].	8.33672e-73
NC_004432.1|WP_011077385.1|716684_717482_-|serine/threonine-protein-phosphatase	gnl|CDD|223704	COG0631, PTC1, Serine/threonine protein phosphatase [Signal transduction mechanisms].	1.03867e-50
NC_004432.1|WP_044891269.1|727919_728405_-|50S-ribosomal-protein-L10	gnl|CDD|240223	cd05797, Ribosomal_L10, Ribosomal protein L10 family, L10 subfamily; composed of bacterial 50S ribosomal protein and eukaryotic mitochondrial 39S ribosomal protein, L10. L10 occupies the L7/L12 stalk of the ribosome. The N-terminal domain (NTD) of L10 interacts with L11 protein and forms the base of the L7/L12 stalk, while the extended C-terminal helix binds to two or three dimers of the NTD of L7/L12 (L7 and L12 are identical except for an acetylated N-terminus). The L7/L12 stalk is known to contain the binding site for elongation factors G and Tu (EF-G and EF-Tu, respectively); however, there is disagreement as to whether or not L10 is involved in forming the binding site. The stalk is believed to be associated with GTPase activities in protein synthesis. In a neuroblastoma cell line, L10 has been shown to interact with the SH3 domain of Src and to activate the binding of the Nck1 adaptor protein with skeletal proteins such as the Wiskott-Aldrich Syndrome Protein (WASP) and the WASP-interacting protein (WIP). These bacteria and eukaryotic sequences have no additional C-terminal domain, present in other eukaryotic and archaeal orthologs.	1.87857e-50
NC_004432.1|WP_052270424.1|709424_710609_-|ABC-transporter-ATP-binding-protein	gnl|CDD|224059	COG1136, SalX, ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms].	1.84719e-91
NC_004432.1|WP_011077387.1|718526_719117_-|guanylate-kinase	gnl|CDD|213788	TIGR03263, Guanylate_kinase, guanylate kinase. Members of this family are the enzyme guanylate kinase, also called GMP kinase. This enzyme transfers a phosphate from ATP to GMP, yielding ADP and GDP. [Purines, pyrimidines, nucleosides, and nucleotides, Nucleotide and nucleoside interconversions].	8.07665e-85
NC_004432.1|WP_011076843.1|724146_725703_+|DDE-type-integrase/transposase/recombinase	gnl|CDD|366234	pfam00665, rve, Integrase core domain. Integrase mediates integration of a DNA copy of the viral genome into the host chromosome. Integrase is composed of three domains. The amino-terminal domain is a zinc binding domain pfam02022. This domain is the central catalytic domain. The carboxyl terminal domain that is a non-specific DNA binding domain pfam00552. The catalytic domain acts as an endonuclease when two nucleotides are removed from the 3' ends of the blunt-ended viral DNA made by reverse transcription. This domain also catalyzes the DNA strand transfer reaction of the 3' ends of the viral DNA to the 5' ends of the integration site.	2.70333e-06

Protein sequences

>NC_004432.1|WP_011077358.1|719923_720940_+|IS30-family-transposase
MFYTTITLNDTNKYRHLSYGEREIIGHMYFVQKKNINQIATELKRHRSTILREIRRNNNVEGYSAEKAQKKYIERRNHKNFFLWQKYKTFSELFAEKYNCKWHGVELTRHYIKENYPCVLVPSTKQIYNWIQTNKWIKKRSDKLRTAYIKGRKRKKGMFSKFDEKYVFPIWMRPKHILNRKEFGHWELDLVIGKRQSGYSNLLVMVERKTRNSFITKVENKNPFTINSAIKSLVNKNNLHVKTITIDNGIEFSKIGIAAYWIKCKVYYCEPYASYQRGSNENVNGLIRRVYKKGTDFSLLSDAEINNLQNKINRMPRKMFNYMSSDQYYKKCMNSLNW
>NC_004432.1|WP_011077388.1|719196_719757_+|peptide-deformylase
MFKKLDPSPKWIVYDNNPVMHKPIEDVVFPLTKEDEHVISQMLSYVDASYEGEADKYDIRAGIGIAAIQLGCPKKIIYIHLDDKNGEHKYLMANPKIIKESTSKMYLKNGEGCLSVKKDHKGLSIRKSIVWVKGIDLFTNKEIEVKATDLLAACFQHEVDHNNNKFYYNRINESDPYYVEKNWEEI
>NC_004432.1|WP_011077387.1|718526_719117_-|guanylate-kinase
MEEKNKKGKIIIISGPSGVGKKTIIDQVINNVDLNLTYSISMTTRLPREHEKNGVDYFFVSEEEFNSAIEKGELLEWAEFANNKYGTPIKNLYKLIGENKNVILEIEVQGATKVKDILNREDYISIFLIPPSIRELKRRLKIRDTETKEKIKQRIKRAKVELKLQNEYDFIILNDDAKNAADKLRHILYEKVLEKK
>NC_004432.1|WP_011077386.1|717468_718527_-|23S-rRNA-(adenine(2503)-C(2))-methyltransferase-RlmN
MLMNSIYSFTLQELKKELTKNNIKAFVAEQIFDWIYSKHVDSFDEMKNISKENIEKLKQLFSFENMVVDKLQVDKHDGTVKFLLKLEDGNFIETVIMKFNYGYSVCVTSQIGCNMACKFCASGLIRKKRNITVGEFIKQFIIAKEYVEKNFNDKLTHMVVMGIGEPFDNFENLIQFFEVIKQQKGLCISPRKITVSTCGLVEKIKEFADLKNQVNLAILLHAPNNEIRNKIMPINKVYSLDKVIEAMDYYIKVTKRRVTIEYILIKDVNDSDENAVELAKLLKGKLCYVNLIPYNKVVENNYFRSVRGKQFFDVLKKNNIQATIRLERGSSIDAACGQLRIKKILELRNAKV
>NC_004432.1|WP_011077385.1|716684_717482_-|serine/threonine-protein-phosphatase
MQKFNLEKFFNNNNNFIKLRRVLYSKSDTGTRQKNEDYAYCGTNKLLDNLLIVCDGIGSCRGSEKAAEIVAKTFVNSFLKQEYLLTNVNEWFEKNIERAKFAMIDHVLRFKDHNQMCTTLVLALSVEDTFHVFWIGDSRAYLIDKKSFEQLSDDHNLLNYLIKTGTPQEEIEAKGKKIYSLMNYISINTKDKQEYDYVSFKIKKNSFVFLASDGFYNFFSDLGSLYDILSHDGNAENLSNDLVNYALNNQSNDNISFSYIGFLKD
>NC_004432.1|WP_044891382.1|716097_716577_+|peptide-methionine-(S)-S-oxide-reductase-MsrA
MKKIYLAGGCFWGIEQYYNLNQKIISTNVGYLNSKIDNPTYKDVCNNITDAVEAVELTYDDQVISLNEIIDLLFKVIDPTSINKQGNDIGRQYRTGIYSRDSNELMAIQEKINELQNNYSKLIQTEVMLVDNYYLAEEYHQKYLEKNPNGYCHINLKAK
>NC_004432.1|WP_011077383.1|714797_715439_-|hypothetical-protein
MKNGKSKIDYKNTQFKNKERISKYGEVFTSQREVNEMIDLVSHEAIRLESRFLEQACGEGVFLMEILSRKLDAISKKFKRYKQDFVKNTIIAVSSLYGIDLLKDNVEKCRDNLLKIALNKYKGFFKDQNEKFVKTIKFILSVNIVCGNCLTMKDNNGEFIIFSEWSPLNDLYIKRTEYLFSELTDSDKDFFIPKELKEYKPIKYFDIGDIYEQ
>NC_004432.1|WP_052270425.1|713278_714808_-|Eco57I-restriction-modification-methylase-domain-containing-protein
MNNNHNPDVLNCIANLSSDEIFTSPEIANKLLDLLPREIWKNKNIRFLDPCCKTGVFLREITKRLIKGLEEEIPNLEKRINHILLNQVFGLSITELTGFISRRTLYCSKKANNKYSICDSFKDESGNIKYLLTDHMWNKDTCKMCGASVLNYSRSEKLETHAYSFIHFENLNEVFNMKFDVIVGNPPYHLSDGGGGIGSSAIPLYNKFVEQAIKMEPRYITMIIPSRWMIGGKGLDEFRNYMLACNKISTMVDYVNSSDCFSGVDVNGGICYFLWEKHYSGKCNFVNVEDGNTNTSSRYLLNGNKDFIRFNKAVSIVEKIKNHPSFKPFSSIVSFRNPFNIPSNANLKFTNPNNLLDLTKIYGFNKGRYEKFLHQDVLIEKNIVLRDRWKIFIPKAVGDANMKKRGLFLKPIKGIINSVCTETYLAIGPFDTEKEVDFCIEYMKTKFFHFLFGMKRISQNTTKETYDFIPLLDFSKIYTDAELYTMFQFSDEEINYIENIFSNKEFVNE
>NC_004432.1|WP_011077381.1|710796_713286_-|DEAD/DEAH-box-helicase-family-protein
MSNNYFQKQTNKIGKIYAYYDYRNNKEMKVGYTTRENPEDRIKEQFPVSAPVKKPFTMFFAKNAIRNDGTTFTDIEIHNALSRLGVQRKNGEWFDYNPEILNKAFFEVKHNKLNFEVNRTKDFSLREEQKEAIRVTKNYFLKNANEKYCKFLWNAKMRFGKTFTAYKFIQEMEYKNVLIVSFKPTVKTAWREDLQSHIDFENYIFINNLDKDETFKTLQKNSGKNIVCFSSFQDLLGKNKYGGIKVKNQWIHNNKWDLIIIDEYHFGAWRERSKDLFNEKDDDFYNSIEIMDALGIEQFPIKSKRYLYLSGTPFRAISNGEFLEDQIFNWTYTDEQSKKEQYKNDENNPYRCMPKMIMLTYKLPDNLREVALKGEFDEFSLNEFFSAKFNERNKKYEFIHGDQVNQFLNFLTGKHTIYLNERLKARDKQAPMPFLDEILLNNLSHTFWLLPNVASCYAMYDLLRETIEFKKYKIILAAGGKSKSGESLIEEIHKNMENPIETKTITLSCQKLTTGVTIRPWSGIFMLRSLKSPETYFQAAFRVQNSWTFKDDYNEVSKEENYKKECYIFDFDPNRALKQVVEYSQNLNTSNKVSTESKVKDFIKFLPILAYSSDTNIMEEVDAVKILDYTITNITYNMLVRKWESAMLVNVDNDTLKRIVSNKQALDILSKLEDFRNLNKDISIIISKSEQIKKLKTKSTESELTKEEKKLLSNDKKDEQSKRREVQKKLIKFATRIPIFMYLTDYREETLKDVITELEPDFFEKVTGLTIKDFDFLVSLNIFNEKIMNDAIWSFRRYEDSSLKYTGILKNKSEKIGLFNTKIVYYEDN
>NC_004432.1|WP_052270424.1|709424_710609_-|ABC-transporter-ATP-binding-protein
MNTKNSFDSINKKFESIYKMAESLVKNKNKNSIAYRAQIANAIEVLYNGLLELNELKPTEKKEIKLVKEIRTTFLSFLHKNITYIEQANWVNRNQTQMDNENLILKINNVSKYYSSKKMAIRVLQNINLEINNGDFVVFLGPSGSGKTTLMNLISGIDRPTTGNLWVNNYRLEEMDEKKLTIFRRNNIGYVFQRYGLLPNLTVLENVLMGSYLGKSSNSFLDNRIYKNTSYSKEELKKLNKDEKEKNNLNRKEELAKIENILKGLELFEFKDKYPYELSGGQKQRTSIARTIAKNPKIIFGDEPTGAVDSEMSGQIVKLFQKINEELKTTIIIITHDETIANYANKVFYILDGKLNRTVVKKKGEPIEMYNNKNNGISELEKSTNFINKTFKQI
>NC_004432.1|WP_011077390.1|721636_722152_-|hypothetical-protein
MDQNNKNNNKPFKGQFSEKEFISVIKGCKIVNVDHFITDSNVFVDDKNNVRIITTRAKCYMEIIKTKKEKLINEVIPPPKDKDSSIEVILGKILDKMEVIELDLKTLKEDVAQLKTDMVEVKSDVAQLKTDMVEVKSDVALLKQDVAILKADMIDVKSGKYCKNHNLYENA
>NC_004432.1|WP_011077392.1|722713_723904_-|acetate-kinase
MSKSILVINAGSSSLKFKLYDWNMAELVSGICERIGIDGFFKIEYKSNHETKKYEGNADFQNHDLAIDYLFNKLVELKIVDNLEDIVGVGHRIVQGGSLSESSLVDDKILKIIEDCITLAPLHNKPEADVLKIVMNKIPNTKNVAVFDTSFHTSIPKINSYYAIPKEWIENYGIKKYGFHGTSYRYITEKMHDILNINRPLNLIICHLGNGASVCCVKEDKSFDTTMGLTPLCGLIMGTRSGDIDPSVFDLVAKETGMSAAEIFNKLNKESGLKSICGSSDFRDIESNTQPGNDYEFATEIFVQRIVNYIAMYKNMLEDKVDGIVFTGGIGENVWNVRKQICQKIKGLDLNPSINETRVGEWARISQPLSRHKVFVVRTNEELKIAQDTQKIVSNN
>NC_004432.1|WP_011076843.1|724146_725703_+|DDE-type-integrase/transposase/recombinase
MSLKKTNQLFVILSLLEFNLVRCFFMKEIIKNNLTKFENSRFWILEEMGSLNKKGKLNPKTLSNKTGYSIKQSRRFIKSFKDNTFLISHKNKNKENVNKIKDEVKRAIIEKYIEVTTPCKEMSDGHYEMTHLDFYLDEIKDKFNVKYGFVNKLLNENFLLTSYSKKITRKTMKKKLKEGNLAELKIQEKILEFLRKYKPTYTEYLKTKNPPYVKHNYDFGHIVEVDACVSVWIGIKKYYIYHAIDAGTGKLLGFWIDDEETNFGYCKLLKQVLEKYGAPNIIKTDRRKTFWSENSVTNLTYCLNKLEIQVKSESQPTFKANVERSFKNAQQIYYKLFLKHGLNTKEKIQKNYQLIVDAYNQRYKKSEKGKRNQFIKISKDDLKDLFYTTKICKVLKGFYFFLNGKAMGLFTKEDKRVNMKNQILLRTNMLTGEKFVLDKNTKYFAREINDDLLNEYINEIHDNEFLKLEKIKRKSIATSKAIYQKNENTRIALERWSDSLKEREEKIKIREIELSLNI
>NC_004432.1|WP_011077395.1|727526_727892_-|50S-ribosomal-protein-L7/L12
MAKLSAKDIIDSLKEMSMLEIKDLIEAIETEFGVSAAAPVAVAAAPAGGAAAPSEVTVTLKDVGGNKVAVIKVVREITGLGLMEAKALVDNAPSKVKEGVKLADAENMKKQFAEAGATVEW
>NC_004432.1|WP_044891269.1|727919_728405_-|50S-ribosomal-protein-L10
MKKIIQFKDNLSSEISEQIKSSKSFIIFEYLGLDAATITKLRKDLFKTGSKLLVLKNNILRRALEKANIKEFGDLVGPNAIVWGTEDEIAPLKEVFNLTKDNECIKIKGSYVEGTFLDAQKTMSIASLPNREGLYSMLLSCLTGPIRGVLYALKAVSETKN
>NC_004432.1|WP_011077397.1|728691_729429_-|glycerophosphodiester-phosphodiesterase
MHKKVDISKTHTKILAHRGYSGIAPENTELAFETAVNFGFDGFEIDVHLTKDNQLVVIHDEDTYRTSLVKKMIKDSTLKELKELDQAAFFKINCPKQEILTLKELLDKFLYRISYLNIEIKTDIIVYPNIEKYLDELVKTYDDAYEKIIFSSFNFNSLKTLHELNPKWTNGFLWWTKSQFKAVNPEEIKKVCKYLHPWTEIYKKEKDNYLKLGLPFNLWTIKDAKVYEHYAKDKDVHFLISNYKY
>NC_004432.1|WP_129374455.1|729421_730894_-|MFS-transporter
MKANKKKDLSMWAKLKSLGPKTIIGILLLGAADCFVIAAPYYLKSLVPNLQVYLNVSEADVSTMTSIIGWVVLLTQLPGGWLADKISSKKLLSIATIMTGVITIWFGTLIIKSRDLDYVNLKIQYFIIFGLWGFATTPLFWTPLWKLVSQQGNKDNQGLVYGLQGSLNGIVGLVFVFGIGTAVSQVIEYNAGNTAITPEALEAQPGLVVPFAIYIYIFAACLLLIGVLVFFFVVEKPTSEKFAVNIKTFARVLQDWKLWALSVFLMGMYMFQSIFAYYLNQMLANVLLMPTVALLVISGFRLYGLRFLVSAWIGKKSDSFRSLTLLLLITLTVGLVIVAIFLFLPGISPSGTLNYFQTLSDGYKLFAMIFMSGLFLISSFLSWVMVTLRYAQMSEIQIPKNSYASANALMSFIGFSSDAWFYQLGSAIASDYTDPNTQVVTQTGYQIIIGIGMIVALIGLVAGFLVYWTNNKQLSKHNINYFRWRALNNA
>NC_004432.1|WP_044891270.1|730910_731348_-|TM2-domain-containing-protein
MEGKKQKKKYFLTQEEIIEDSKKANELKQQGLIYDREIPEYWSSGTSPYKKKTNLLLAIFLGFFGADRFYLKKYISAFIKLFFILIVTPVSIYLTVDPNLALYAAYPDIVIVFSILFYGTAAAFYFGDIVIGIVKPRDYDFQNLN
>NC_004432.1|WP_044891271.1|731732_732668_-|hypothetical-protein
MFKKKKIKTPFVVVLSFSRRTVAEIAKNTLSDKQILDKKLLKEKSYFSSEDYTFFNFVNDDNKVFRVIFQLVMKEKEKNKKKLFSELKYMFDCSDIEIINKQDFDFSKYNVNPLVRGEVHNFHTASKDEKIEESKPSVKKEVQQSPNIATVANEKYIAQSLESNTNADNKLNHYQQQNNNQLNGPQNLNSSINNANLVNPGSPANPVNPIIQQDPIYRNSNVANPANVLALKESNLNEINNAPVVSLSQQDNVNVPINSNQPNPNNFQSENVLNNNGANPNIPNYNNPNSFQNKKEDDVHYVKYNKENPFE
>NC_004432.1|WP_011077401.1|732759_733620_-|hypothetical-protein
MAKKIISRKKKDNQLIKSRVIEIKINEKTVVYIDEWYLEELVDIVKQYPGEKYAEMINQMIINTKRKKPSFPQLNLASHRVIDKKSNFFEFPTMEDYINETWLNQEKISLLKVNSVKKMRVKFSTVGGVPHIPSYLNNLSPNNMLTFIKEKSIIFKKATILINVSGNMNWKDYRKIIRDYFKLYDFESLSLGNISKTTENKIDYYRISIVKIRNGVNVNGQGLMFESADFLRRMMFMIYEIDPTNQYWNAYGNTIYNKDIQKLKEAEPYFTTILERYLNPSLILVE

Crispr_ID: NC_004432_3

• CRISPR_ID: NC_004432_3
• CRISPR_location: 1075257-1075351
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers
• Cas_protein_info: DinG

Consensus repeat of NC_004432_3

Consensus_repeat	Method
AACAACCAGTAGAATATGTTCAA	CRISPRCasFinder

spacers of NC_004432_3

>3.1|1075280|49|NC_004432|CRISPRCasFinder
GATCAACAATTTGAACAACCAGTAGAATATGTTCAAGATCAACAATTTG

CRISPR arrays and Neighbor proteins around NC_004432_3

CRISPR arrays

The CRISPR arrays of NC_004432_3

>merge|NC_004432|3|1075257-1075351|CRISPRCasFinder
ATCAACCAATTGAATCAATTCATGATCAACAATTTGAACAACCAGTAGAATATGTTCAAGATCAACAATTTGAGCAACCTGTAGAATATGTTCAA

>NC_004432|3|3|1075257-1075351|CRISPRCasFinder
ATCAACCAATTGAATCAATTCAT	GATCAACAATTTGAACAACCAGTAGAATATGTTCAAGATCAACAATTTG
AGCAACCTGTAGAATATGTTCAA

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_004432.1|WP_044891299.1|1080742_1081447_-|LemA-family-protein	unknown	unknown	gnl|CDD|224618
NC_004432.1|WP_044891297.1|1059325_1062895_-|hypothetical-protein	unknown	unknown	unknown
NC_004432.1|WP_011077630.1|1084732_1087147_-|DNA-polymerase-III-subunit-gamma/tau	unknown	unknown	gnl|CDD|235638
NC_004432.1|WP_011077617.1|1071968_1072748_+|hypothetical-protein	unknown	unknown	unknown
NC_004432.1|WP_011077623.1|1077051_1078464_-|proline--tRNA-ligase	unknown	unknown	gnl|CDD|236327
NC_004432.1|WP_044891298.1|1070373_1071834_-|tRNA-(N6-isopentenyl-adenosine(37)-C2)-methylthiotransferase-MiaB	unknown	unknown	gnl|CDD|184624
NC_004432.1|WP_011077619.1|1074083_1074884_-|aldo/keto-reductase	unknown	unknown	gnl|CDD|381297
NC_004432.1|WP_011077618.1|1072816_1074052_-|tyrosine--tRNA-ligase	unknown	unknown	gnl|CDD|235645
NC_004432.1|WP_011077612.1|1058457_1058979_-|bifunctional-pyr-operon-transcriptional-regulator/uracil-phosphoribosyltransferase-PyrR	unknown	unknown	gnl|CDD|235365
NC_004432.1|WP_011077621.1|1075682_1076396_+|16S-rRNA-(guanine(527)-N(7))-methyltransferase-RsmG	unknown	unknown	gnl|CDD|223434
NC_004432.1|WP_011077624.1|1078465_1079212_-|YebC/PmpR-family-DNA-binding-transcriptional-regulator	unknown	unknown	gnl|CDD|237084
NC_004432.1|WP_011077622.1|1076382_1077048_+|hypothetical-protein	unknown	unknown	gnl|CDD|224113
NC_004432.1|WP_011077629.1|1084441_1084726_-|YbaB/EbfC-family-nucleoid-associated-protein	unknown	unknown	gnl|CDD|234800
NC_004432.1|WP_152023104.1|1062986_1066442_-|hypothetical-protein	unknown	unknown	unknown
NC_004432.1|WP_011077628.1|1083833_1084439_-|recombination-protein-RecR	unknown	unknown	gnl|CDD|234616
NC_004432.1|WP_129374573.1|1066616_1070126_-|hypothetical-protein	unknown	unknown	unknown
NC_004432.1|WP_011077610.1|1056266_1057547_-|dihydroorotase	unknown	unknown	gnl|CDD|236479
NC_004432.1|WP_044891300.1|1081506_1083675_-|hypothetical-protein	unknown	unknown	unknown
NC_004432.1|WP_011077625.1|1079213_1080587_-|DEAD/DEAH-box-helicase	DinG	COG1199_DinG_CAS-IV-A	gnl|CDD|223587
NC_004432.1|WP_044891404.1|1057555_1058443_-|aspartate-carbamoyltransferase-catalytic-subunit	unknown	unknown	gnl|CDD|234849

HMMScan for Signature genes

Protein	Cas_name	Cas_description	E-value	Identity	Coverage
NC_004432.1|WP_011077625.1|1079213_1080587_-|DEAD/DEAH-box-helicase	DinG	COG1199_DinG_CAS-IV-A	3.9e-12	39.9	0.2

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_004432.1|WP_044891299.1|1080742_1081447_-|LemA-family-protein	gnl|CDD|224618	COG1704, LemA, Uncharacterized conserved protein [Function unknown].	1.98891e-42
NC_004432.1|WP_011077622.1|1076382_1077048_+|hypothetical-protein	gnl|CDD|224113	COG1192, Soj, ATPases involved in chromosome partitioning [Cell division and chromosome partitioning].	3.74509e-05
NC_004432.1|WP_011077630.1|1084732_1087147_-|DNA-polymerase-III-subunit-gamma/tau	gnl|CDD|235638	PRK05896, PRK05896, DNA polymerase III subunits gamma and tau; Validated.	0
NC_004432.1|WP_011077629.1|1084441_1084726_-|YbaB/EbfC-family-nucleoid-associated-protein	gnl|CDD|234800	PRK00587, PRK00587, YbaB/EbfC family nucleoid-associated protein.	1.82853e-30
NC_004432.1|WP_011077623.1|1077051_1078464_-|proline--tRNA-ligase	gnl|CDD|236327	PRK08661, PRK08661, prolyl-tRNA synthetase; Provisional.	0
NC_004432.1|WP_044891404.1|1057555_1058443_-|aspartate-carbamoyltransferase-catalytic-subunit	gnl|CDD|234849	PRK00856, pyrB, aspartate carbamoyltransferase catalytic subunit.	3.81511e-153
NC_004432.1|WP_011077619.1|1074083_1074884_-|aldo/keto-reductase	gnl|CDD|381297	cd19071, AKR_AKR1-5-like, AKR1/2/3/4/5 family of aldo-keto reductase (AKR) and similar proteins. Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. The family includes AKR1A/B/C/D/E/G/I, AKR2A/B/C/D/E, AKR3A/B/C/D/E/G, AKR4A/B/C, AKR5A/B/C/D/E/F/G/H, and similar proteins.	1.57751e-71
NC_004432.1|WP_011077618.1|1072816_1074052_-|tyrosine--tRNA-ligase	gnl|CDD|235645	PRK05912, PRK05912, tyrosyl-tRNA synthetase; Validated.	0
NC_004432.1|WP_011077612.1|1058457_1058979_-|bifunctional-pyr-operon-transcriptional-regulator/uracil-phosphoribosyltransferase-PyrR	gnl|CDD|235365	PRK05205, PRK05205, bifunctional pyr operon transcriptional regulator/uracil phosphoribosyltransferase PyrR.	5.52672e-88
NC_004432.1|WP_011077621.1|1075682_1076396_+|16S-rRNA-(guanine(527)-N(7))-methyltransferase-RsmG	gnl|CDD|223434	COG0357, GidB, Predicted S-adenosylmethionine-dependent methyltransferase involved in bacterial cell division [Cell envelope biogenesis, outer membrane].	2.63065e-46
NC_004432.1|WP_011077624.1|1078465_1079212_-|YebC/PmpR-family-DNA-binding-transcriptional-regulator	gnl|CDD|237084	PRK12378, PRK12378, YebC/PmpR family DNA-binding transcriptional regulator.	1.8858e-89
NC_004432.1|WP_011077628.1|1083833_1084439_-|recombination-protein-RecR	gnl|CDD|234616	PRK00076, recR, recombination protein RecR; Reviewed.	1.74842e-69
NC_004432.1|WP_044891298.1|1070373_1071834_-|tRNA-(N6-isopentenyl-adenosine(37)-C2)-methylthiotransferase-MiaB	gnl|CDD|184624	PRK14327, PRK14327, (dimethylallyl)adenosine tRNA methylthiotransferase; Provisional.	0
NC_004432.1|WP_011077610.1|1056266_1057547_-|dihydroorotase	gnl|CDD|236479	PRK09357, pyrC, dihydroorotase; Validated.	0
NC_004432.1|WP_011077625.1|1079213_1080587_-|DEAD/DEAH-box-helicase	gnl|CDD|223587	COG0513, SrmB, Superfamily II DNA and RNA helicases [DNA replication, recombination, and repair / Transcription / Translation, ribosomal structure and biogenesis].	4.09186e-76

Protein sequences

>NC_004432.1|WP_011077619.1|1074083_1074884_-|aldo/keto-reductase
MKKRIGYGSFEVNDVPTLKKCIKQAVLSGYDFVDTAYYYQNEEAIGKAIKELREEGFDKPILVQTKIWPEHYGNVRDAVLLSCQKLQTNKLDMCLLHRRHFNLNMDLSAWEQLIECQKEGLVGEIGVSNFDRDALEIMRQRTGVYPLSNQIELSVNNLREDRVVYNHSKGIEVQAWSPLGDLENNLKNPVLIEMAKKYNTDVAGVLIAYVGSLNCSIIVKTSNPDRVVSNYKAFQIILEESDVEKLKKLNTYKIKYSESFIYDIDN
>NC_004432.1|WP_011077618.1|1072816_1074052_-|tyrosine--tRNA-ligase
MKNKNILEFLKKRGYIYQGSNFDLIEKELIKGTSFYIGFDPTADSLHVGHFLTMMAVKHLQKAGNNPVIVVGGGTGSVGDPSGRSEIRKILDRKTIDYNCECLKKQMSKFISFEGKNKAVMVNNADWLLKINWIEFLREFGVCFSVNKMLAAEAFKVRFEQESGLSFLEFNYMLMQAYDFYYLNQNYNVNIQLGGSDQWSNILAGVDLIRRKSSKEAFALTLNLLTKHDGTKMGKTATGAIWLDKNKTSPYEFYQYWLNIDDQDVERFLLLLTELDDKTISDLCKEKGKKIVEAKKVLASELTKMIHGQEELDKAIEQSKAAFENASDNLPTYELKASDLNNDYSIANILVVTKLSPSKAESRRLITSNAVSVNETKITDVNTKLEDLKIDQTNFTLHKGKKNHIKVIINK
>NC_004432.1|WP_011077617.1|1071968_1072748_+|hypothetical-protein
MKKKLFSRLFKFGLPLVAVAVVPSVVSSCSSTVTTKTKVLNASNWNNGNVKYSELSSSNTSLESATFGSSFNSGNYIFIWGTLADSSFATFLYGSSGASATEEKSFENSTFLKSFFSSELSTSSVFGNVSLLLYIDTPPYNGDVTDNSAGETGYDSPTEQYTLDNVLKEANEGAAVGRYTAETLPLSYQLKVGNYMRGNKEAVTYREFVQYVKTVRPSVSGPENSGIIAFKKGKNPAAFSTSSTISDLTSYYTPSADDE
>NC_004432.1|WP_044891298.1|1070373_1071834_-|tRNA-(N6-isopentenyl-adenosine(37)-C2)-methylthiotransferase-MiaB
MDSKSTKKRDLSKYFLPDIRQARKRIKKADIIKDGFEIPANIINYGEGKTYHIKTFGCQSNLRDTEVMMGMLELIGYEYNEDVNTSDLVLLNTCAVREHAESKVFADIGILDRIKKSNPNFIFGVCGCMAQEEAVVNRILKSNFNVDFIFGTHNVHRILNLLEQVIFEKNLVVEVWSHEGNVIENLPSKRTNNLKGFVNVMYGCDKFCTYCIVPMTRGKIRSRRKEDILDEVHQMISEGYKEVTLIGQNVNSYGIDFDNGENYLFNNLLEDVAKTGIERVRFTTSNPWNFTRSIVDTMKKYPNIMPHIHLPIQSGDETILKKMNRPMKIGDYIDLVDYIRANIPNCSITTDLIVGFPNETKEQFNKTLELYKRIEFDNAFTFIYSKRDGTVAAIIPDEIPLSEKKERLQELNEMVKTFSKKNNEKYVNKVLDVLVDGPSKKDKTVISGYSPQWKVVNFTGSAKSGEIVKVLITSASRFTLNGKMID
>NC_004432.1|WP_129374573.1|1066616_1070126_-|hypothetical-protein
MVGFNNLNKSISSHNLNANSNSVVSSSSNTRASGTWNDESLIAKNDYLSNVNMPNGYLTISETDKTINLITWFGTQSWSYNVANSPFLAQGITGYNAANSTLVIHVYYLANYDRVLVYGTVNSTTTYVFQLNSDGTEYYVNNDDSNKVRNSSLISGRDTGVIGSAYSINLLNDNSAIILPKNFDKNVSTISATKFTFNSFTATPINYDLTGWSTSTDRVPSTAYSTWTFGSIIGVSESSDGSTSYLITKASSANGSTGQTLVHLVYFKFTNNVYETMISKTISHLTTSTVDLEKAYFKMLTTVRDSVPYSYVALVNNISDPNSVKLGAYSGATSSPLDDNNTTLFEFAPNSGTISNFFVMKKAAASIMDIFINPYNSRPYAVIKNYNANNFYFSDLLNNKANAANGPDNYLLSVKKWSNFPSVTSSSDNSRIDLIWRPIFESGVTTPRTVNGIVSVLRYADDATTTVSSSITYRFGVTDFTTASQTTTFIVFNASVINSYQNLTSQYYYLLPQDITNDIFEKFIYLTNADGSGTSANRPFNSNITIPNNSLTINNTNGTLSGTINLNITKWWLTSAAGTGTSNIYTIPVSVNLTGLATNSSLNFQIVNSKDINTTKYNKILEFQRTKYPNEITAQEILDNFIVFGNSLRLTTANVLMINANSNSGNTTPQSDQYITVTANNDDGTLAISWNLTSIISPSITVKSGSYTFNNFKHLNAWNQITLNDRVWNTLKTSKSPFQINVEDIISALNLSSGYVNDPSYWTWSPTYSESNNKVNYVKQSVDGNFTGTITYNRDKAGVPSTVPESYTKFEITSTHGTGFLTIDKLLGSHFETTLYYNENAASKLASSYDLSKVESDFANILENSLVFYNGWTTSSSVNYQITSTNNSQIVFSLSYKDNIETNLKKADGTNLVLDSEWINGIQSSNNNVLNLASSYSFAYNLTSVEYNYNLTTVDNKIDIKSVLNSSTTSSIDYTGMKASKFISSFYNGQTNSYDNFLKAFDLVKLPTNTSAINYYYISDVQLTSDDVNGTVTIYYTFTFPNAGDVEGSSSTSSIILSGFLTNQSFSNNWLIICSAIVGIILLMLASGSTSIFVYKKRMNKKRINYGLGSKDYELNLEKVQRNFSKSDIHKHRVRNTINSYHYGNQNSRANRDLKTYSKKLEEVKKMKK
>NC_004432.1|WP_152023104.1|1062986_1066442_-|hypothetical-protein
MIGFAVGFSNINNLASSEIASNYNAANSTRASDTWTDDSLIGANDLLSNPNTPNGYLVTNGTTINMITWFGSQSWSYNLSSSPFLTQISGFNTSKPITSHVYYLAKYDRILVYGTYDTSTTYVFQLNSDGSEYYVNKDDTNKVSNSSLISSSNSSVIGSVGSINLLSTESAIILPKTIDTSTYKLQATKFNLENFSTVAATYDASDLKTSSDAGATSIKTGYTISEIIGLTESSDGKISHLIMKGYSNGTAASTKTVSIAWIKLTNNVFTSAGKIDIATVSETGFNIDNAKFKLVNTFPTSGPVSYVSSINDISNENSIKPGVASDSSQNANQVIEINNNSSNMIKFFTESSKQGSVLDIFNNPYNNRPYVLLKHHQYNQLYFSDLLANKNNSGNAQDYLINIKEWSNFPGINTSNDTSRIGLIWKPIFENTSNVPTVIKGLVSSLTYANGSATPNTKLTRKFTITNFTTSTQQTSSYEDFHATILNSYTSLATENSHLLPQDIDNAIFQKYIYLKSVNGSTTNSPYTSTIIIPKDGLTISNDNGTIKGTVNLNINKWWLASGVYTIPISIDISGLATNSTSNFKIVNNSEINPNKYKKILELQKSKYPSNITAKEILDNFLEFGSSIKLTEANISIVNKTKNASSNTNTNTGTDKYITVTTNDDDGTLSISWNLTQIMSPSVTNRNGSYVFDNFLNLNAWSKITLNEKAWSTLKTSKSPFQVSVADIINSLNLSSGYKTEPQYWIWEPTVSIASNKEAYVKQSIDGNLTGKIKYNKTEAGNVTGNVQDTDLEFTIDSSKGSGFLTIAKLLGGNSTTTLYYNENGASKLASSYDLSKVESDFSNILANSLVFYNSWTTSESMKYTITSNVDSKIVFTLDYKDSIQTNLETGDGSKLVLDAEWISAIKTSNENVLALSSSYSFSYNLTSVQYNNNLNSTNNSIGITAIDESNQTYKKYSEMKPSKFINSFYDKQTNSYRSFLDSFDLVKLPTDTKAINYYYVNDIQLTSNDAEGTVTVYYTFVFPNAGDIEGSSSTSSIILKGFATNQTLSNNWLMICSIAVAVILLLLASGLGSVFFYKKKINTKRINYGIGSKNQELNLAVSQRQLGIFNVHKNKIRNTINGNNVVNTKTGNAKAKQYMKLLKEMKKSER
>NC_004432.1|WP_044891297.1|1059325_1062895_-|hypothetical-protein
MFANKKRLFKTILLSVSFSIIGSMVGLSIGLKNINNIVQNNVSENSNLYSSSSSNLNSKTTNWNDESLISNNDYKSNPNTPNGYLTVTDKTINMISWFGSKSWSYDVSNSVFLTQANITGYNPSSSTISIHVYYLANYDRILVYGTVNSNVTYVFQLNSDGTEYYVNDSDTNKVANSSLTSTRNSNVISSVNSINLLSSDSAIILPSNINTTNYQLEATKFSLVNFSAVKTTYDASEWTINTDATLTNIRTSYTLSGIIGLLQSYDATTSYLILSGHKQGTNANLKYVSIICVKLVNNTFSTANEIIFSEVSATNFNINNATFKIVNSFANNIPVAYVSLVNDISNPNGIKTGPDSSATSSWGNSKNINQVIEFNGNDGVQNNYYVSPTTGGTILDIYINPYNSNPYALIKNKSENTFYFSDLLTSKVAGKTDQLIRISNYRFFPNVTSVSDTTRINLIWRPIFEEGIGNVTVLKGLVSSLTYSDATSTTPNSTNTKRFTIVNFTPGRNQNVTFDDFYATTINSYENLVTNYYYLLPQDVSTTILEEFIYLKNISNNNKVFTSSIVIPTNGLTVLNDKGTVQGTVNLNVTKWWLTGTATSDTSNFFTIPISINISGLATNSTLSFKVVNNNEVNSTKYQNILNLRKTKYPSAITAAEILSTFLDFGSSIKLTEANILMKNNTSTNDNTTPSDTQYITVVANDNDGTLSITWNLNSIISPSVLERSGSYTFNNFLYLNAWSKLSLDDKAWNTLKASKSPFQVTITDIIDSLNLSSGYSKDPSYWTWTPTYSLTSNKTQYINQSLEGNLTGTIKYNRSLGQVSSSVPDSDLQFTIDSTKGAGFLTLSRLLGSVSTSTLYYNQNSASKLASSYDLAKVESDFNNILFNSLSFYNDWTTFENMNYNIISSSNNTIIFNLSYKDNISTNLKTADGSNLVLDSDWINAIKASSNNVLNLDASYSFSYSLTSIEYNYSLTSTENTISIESVVKSSSSLNLDYSKIKASKFVNEFYNSQTNNYSDFLKTFDLIKLPTDTTAINYYYISDVQLTSDDVNGTVTVYYTFTFPNAGDVVGSSLTSSVVLNGFVTNQAISNNWLIICSIIVGIILLMIASGSTSIFVYKKRINSKRNKYGLGSQEQDLNLEYVPRKIQHSARPKRVRNTINGHCLSNKNRTSNYINNYSKLMKQMKKQKRK
>NC_004432.1|WP_011077612.1|1058457_1058979_-|bifunctional-pyr-operon-transcriptional-regulator/uracil-phosphoribosyltransferase-PyrR
MKVLLDESGIKKSTMRISYEIIEKNKDIKNIVLVGIKKRGDVLATRIQKNIFELEKVMLPLETLDVTFYRDDQKDRNFSKAIESTNFETDLNNKTVIIVDDVLYTGRTIRAALEAILINSRPSKIQLACLIDRGHRELPIRGDFIGKNIPTSSDEQIQVFLNEIDNKEGVEIL
>NC_004432.1|WP_044891404.1|1057555_1058443_-|aspartate-carbamoyltransferase-catalytic-subunit
MTNLLSIDDLTNEQILNLIKRAIDIKENNNQIKRDDLYVANLFFENSTRTKMSFVVAQNKLGLKSIDFEVSTSSVNKGETLYDTCKTLEMIGVNMLVIRHSQKQYYKELENLEIPIINGGDGSGEHPTQCLLDLMTIYEKFKSFEGLKIAIVGDIKNSRVAKSNYKALTKLGAIVHFVAPDKFKDDEFNNYKEFDEIINEIDVCMLLRVQHERHESQDKTQEFINIYHQQHGLSLPRYNKLKENAIVMHPAPVNRGVEIDTTLVESDKSVIFLQMKNGMFMRQAVLEYIIAENNL
>NC_004432.1|WP_011077610.1|1056266_1057547_-|dihydroorotase
MLLKNCSILKNNKLIKSDILIKNNRIIKIAKKIENKNNEEEIDIKSNLVIPGLIDVHVHFREPGFIHKETIKTGSMSAAKGGFTTVMTMPNLNPVPHNLENLNVQLDLIKRHSVIRCIPYGSISVDENGEQLSDVENLSKYVFGFSDDGKGIQNNNLMYQAMLLAKKHNKPICAHCEDNSLANKGVINEGVASEKLNLKGINPLAETIQIARDLVLAKATKCHYHVCHVSTKESLELIKEAKKKKINVTCEVTPHHLLSIDQDILNDNGKWKMNPPLRSIQDQKALIKAVKNKLIDIIATDHAPHSKQEKNCSFNDAAFGIIGSEFAFSLLYTKFVKTKVFSLQLLVDLFTKNVAKIFKLPYGVLEENKIADLAVFDLNKSFEIKEDEILSKSKNTPYLNQKVYGVSLLTISNGKIVYLNEKELSV
>NC_004432.1|WP_011077621.1|1075682_1076396_+|16S-rRNA-(guanine(527)-N(7))-methyltransferase-RsmG
MNLKDLIKLLEVKFPQIDSNEVESKITIYKNYLQQENKIHNLTRLDKEEEIYQKYFYESILNFHNDLFDNKNINLLDIGSGSGVPGIFLKILFPHINLYIVESNTKKVNFLNNLVDKLELENVFISNQRCEDYIKDKIEFFDLITCRAVAELRILLELSFPGLKINGIGFFLKSNNYLVELDNAKNISSKLKIEEEPKIETIEYDGKTFVSLKYIKKNKVNNIFPRTWKEILNNDKN
>NC_004432.1|WP_011077622.1|1076382_1077048_+|hypothetical-protein
MIKINFIGLKDGGKSLSCFLLAKFFSKKNKTLILNIDLFSKYGLFLKKNLVTKKLEWNNKTIKLMPVNTNLDLMDLNINPDLQDNLENLIEYLSNSYEVILIDNLVALPSININVIHNSNFIISPFKIGQDILSFKNKVLNLFLSNSINSSNFKFLPLLSNNNTINMNEMLRLRKQLSSILFDIPIPYCEFKKYSDLAKNTKLLNQYNLVFEEIKNKIEIK
>NC_004432.1|WP_011077623.1|1077051_1078464_-|proline--tRNA-ligase
MSKIVKQEENFSKWYTSIIENANLVDYGLVKGTIMFKPYGFAIWKRIQEEFNKILVSLNTAEVCFPMLIPYSEFMKEKEHVEGFNPELFKVSHLGEKKLEDELVIRPTSEISFCNYFKKNIKSYNDLPCILNQWGSVFRVEKNTRPFLRTSEFLWQEQHAVFADKKEAFDFSITMVNEYKKFVNDYLSIAVLMGEKTENERFAGADNTFTIEALMPDGQVLQSATSHYLGTNFAKSYDLKYQTKNNNYDLMFQTSAGLSTRIIGAIIMSHSDNNGLVLPFKIAPIQFAIVTSNEVNKDSDELKAIYKNLFGYKYQTYFVEKSLGLQLQENEIKGIPFQLILGKKEIENNTITIYRRDTREKQNISFKEFNQNFIENLIKEYSSNLFNKTEKRLNSSIEFVNNIDEFKKALDNKKIISAYWSGNAEDEKKLKELTTATPRCFDWNQKIDKTKKCFFTNKPNAKLVYFARAY
>NC_004432.1|WP_011077624.1|1078465_1079212_-|YebC/PmpR-family-DNA-binding-transcriptional-regulator
MPRKHLIASGINKKQQTQAKLGNKLAKEIKAAAKVGGPNPEANPRLKAAIDKALQNNLSKESIEKNINGSIKDPSSLTDAEYEGYGPNGLRIIIKTLSDNDNRTISSLRGYFSKLKGEIAKPNSVKNSFIYGGEIIISNKDLTEDDLMEKILLSLEKIEVTDNDEPIQETNQHEDCFQIIVMPKYFYKIRQELETLGLKIIESEIKYIPTDYVDLNKEDYARLERFLDSCNEDDDVQWVISNFGEVIE
>NC_004432.1|WP_011077625.1|1079213_1080587_-|DEAD/DEAH-box-helicase
MIKEFKDFIQTTLTSEMDIKELNVLQTESIPIINKDKNVVLVSQTGTGKTLCYLLPILENINLDSKELQAVIVVPTKELIRQITKILSFFKKHNNKLSYLSIVNNASNVDFALESKSPNHQIIVCSPSKFNELTKYKTYVRSLQYIVLDEADMTLDLGFFGLVNQAFSSLKHINNIKKIATSATLHESLSVQVSKFFKNSIIIDKSKNIWENPNIKHYVIHYNHNEDKNKMLLNIIKKLNPFFGIVFCNTKKEVDALYDYIYQNKIPVLKLHSGLENRQRKNIFREIKENNINLLIATDLASRGVDIEGASHVISYDLPKEDLWYVHRAGRSGRKSYKGASYVFNDSNSIYQIERLSRKGIRWNHLKYYKHNLNEYQFKFKTRVKKETKVDLQIRDVINKASKKVKPNYKKKIKLQIQEIKRKAKRERIEELVNQQRLKKYKMESARKTRLKKERGY
>NC_004432.1|WP_044891299.1|1080742_1081447_-|LemA-family-protein
MLVDTRIPQNPQGFNLNVDNTQRVAKASAAQKFGWILLIILTFSVIYWISISWKNQFIDSQMRINEASSAIQVNEAKRRDTLIKLLEQTKGYMKHERETLELVTKYRGGVANSNETSKLDNQLSQFMMNLNVQYEQYPQLKADAIITELMSTSQYLETEIAASRRLYNQKVTSFNAEIFMFPKIAVASKIGLATFPMFQASAVQRQDVDMSSLTSYNTPTPAPANGGSTPAVVQ
>NC_004432.1|WP_044891300.1|1081506_1083675_-|hypothetical-protein
MNSEKDKILLSETKEVNNELEKVAYQAEQITELDNGPVKQTEAQPNLNNNNISNAAIAGAAMNMVQNFIVNPNEKNNQNGLNKNSSASPIKERNLTINYSAVTNNPIEMFYNHINNTIGTVFDDYFAIKFNQYKGVVKKTYELDLQITDLEGSIINKKKELQYTKRKWIHALFIISFVFIIGLFFFKKYKANLAMINQFKEFKNQQENNILDTSNNRFALMHSLLSTITLYDLYKYTFERYGFKISELIPTTRILKLLDNKNNIDVKCGISGLYKNTPFYDVLVRSLAWREVTTSRSESFPYTSYETVTDSNGKRRTVAVTKYETLTAYHHENTPFIDADNVLVFMTHYEPQLLFSTNNKKPNKYIELENKNFVKLYGLDVSGDAKNDISIQQRVNQFFTIKAQEDYLKWLDLNGKYTFDFFKLKDSFNIFNTSHDIFPLEAANHFIEDINILENNAEVNLDVLCNRIKDIAFNYFNKIIKMLQLPLLSPAINREWYKHNSNNYTIGNNLSEVYDDVDNISNFDSNYNALRFLDPKFFWFNTNKKPTKPIWFRLNESVKNKKDIIHFHYNMNSYWSETLIDYVTVVGMHVGTKVIGVPYEKFYFFTEEKFLSNLFANNKNVPRIYITPNVRHLIGKGTYENQEFVNLMIQKGIWCSNPNWLENFSRTKQLVTISDKLNEYNKDAQSSIVIDQYGFYFISNNKDTKNEFVESILLELKSIFSM
>NC_004432.1|WP_011077628.1|1083833_1084439_-|recombination-protein-RecR
MKPKEFEYFVEALKSLPTISNKNASKIAYFFLEADEVFYSQFLDRLTSLKSNIKFCLNCNNLTSDSLYCDICNTDSRDKNKLCIVSYLEDLEKIEASNSFSGLYFVLNTEIKHKDLKTAKKINLEKLENMINKFHVREILICTNMTIDGELTSSYIKNFIKEKNYNIDLYRLALGIPMNASIEYIDWESLKYSIENKRKID
>NC_004432.1|WP_011077629.1|1084441_1084726_-|YbaB/EbfC-family-nucleoid-associated-protein
MNMQKMLQQAKALQSKMEKKIKEFEQEEFEFVYQKSITIQIKGNYEIIKMDINKELIDPEDKTMLEEMISEAINEAISAITEEKEKITKGAMPF
>NC_004432.1|WP_011077630.1|1084732_1087147_-|DNA-polymerase-III-subunit-gamma/tau
MNNKIAFYRKYRPNSFNEIIGQKFIIKTLSNSIIKNKQSHAYIFSGPKGVGKTSIAKIFSKVLNCLNLKDGDCCNNCNNCNLINQNQAVDIVELDAASNNGVGEVRNIIDTINYLPSVLKYKVYIIDEAHMLSNAAWNTFLKLIEDPPKYLVFIFATTESYKFPPTIISRCQRYNFLKLNNSELKECLKSIAKKEKIKVEDNALNKIAELADGSLRDACSLIDQLDSYTNSDIKIEDIYNVFGILDVNEKINLLKSVWNSNVEQIINKINEYEVKGIDFYQLSIDLINLLYDKLVYERTKNVSLLKYLPSEQTNFLELQPKFIIKCLEVWQDNLNKIKTSSNPKFYFQLSCFESCKLFEFEFDTNLTANSYVVKNETELKEQLEQKVKPTKKETVKVELTEKNKPDKLKEEIKAEEIKVKPSKKEEIVEEKVIEQEKENNSAQEPILDTSNFKQVKLSESMKVVQIKGKPEGKKEVIEPQNKKINIVDNFVDNFVQVDHLDKDSDIFDEFGIVGKKSKAKTNKANKPKEVIKEEVIEKEIVKAPEVVVEKTEKKKPKTKSIESSSEQLSLFSFDNIEADSPTDYLEEQFESIEEENITEDSNVNTKKGNVDPTKEPIELPKDKKENKVEKKEEIAKPITQSVNKVKEEESFKEIDIDEAFLKIAVNSNNSEKEKVNNFFKSIKDSMPSNSFESSIKQMDRLIVVSNNGIAFSSADDLEIENINKINQSLEFLEYLKNKLNKVYLVIAITKDQAIKVGNEIRNNKLSPSNTKDVDIEFLNTKIKSKPTAKDLVESMLSELIIDEE

Crispr_ID: NC_004432_4

• CRISPR_ID: NC_004432_4
• CRISPR_location: 1330257-1330351
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NC_004432_4

Consensus_repeat	Method
TTTTTTTCAGCTTCTGCTTTTTG	CRISPRCasFinder

spacers of NC_004432_4

>4.1|1330280|49|NC_004432|CRISPRCasFinder
TTTTTCTTCAGCAGCTTTTTGCTTAGCTAACATTTCTTGTTTTTTAGCT

CRISPR arrays and Neighbor proteins around NC_004432_4

CRISPR arrays

The CRISPR arrays of NC_004432_4

>merge|NC_004432|4|1330257-1330351|CRISPRCasFinder
TTTTTTTCAGCTTCTGCTTTTTGTTTTTCTTCAGCAGCTTTTTGCTTAGCTAACATTTCTTGTTTTTTAGCTTCTTTTTCAGCTTCTGCTTTTTG

>NC_004432|4|4|1330257-1330351|CRISPRCasFinder
TTTTTTTCAGCTTCTGCTTTTTG	TTTTTCTTCAGCAGCTTTTTGCTTAGCTAACATTTCTTGTTTTTTAGCT
TCTTTTTCAGCTTCTGCTTTTTG

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_004432.1|WP_011077825.1|1326452_1326875_-|50S-ribosomal-protein-L16	unknown	unknown	gnl|CDD|236411
NC_004432.1|WP_011077829.1|1329105_1329522_-|50S-ribosomal-protein-L23	unknown	unknown	gnl|CDD|237035
NC_004432.1|WP_044891325.1|1341771_1342620_-|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl|CDD|224059
NC_004432.1|WP_011077837.1|1334574_1337958_-|preprotein-translocase-subunit-SecD	unknown	unknown	gnl|CDD|237276
NC_004432.1|WP_011077833.1|1331693_1332524_-|Cof-type-HAD-IIB-family-hydrolase	unknown	unknown	gnl|CDD|369792
NC_004432.1|WP_044891324.1|1341226_1341685_-|2-C-methyl-D-erythritol-2,4-cyclodiphosphate-synthase	unknown	unknown	gnl|CDD|178851
NC_004432.1|WP_052270432.1|1325731_1326460_-|50S-ribosomal-protein-L29	unknown	unknown	gnl|CDD|238243
NC_004432.1|WP_011077823.1|1324475_1325729_-|30S-ribosomal-protein-S3	unknown	unknown	gnl|CDD|234722
NC_004432.1|WP_011077822.1|1324181_1324457_-|30S-ribosomal-protein-S17	unknown	unknown	gnl|CDD|235532
NC_004432.1|WP_044891436.1|1333336_1333960_-|ribonuclease-HII	unknown	unknown	gnl|CDD|260003
NC_004432.1|WP_044891323.1|1331114_1331423_-|30S-ribosomal-protein-S10	unknown	unknown	gnl|CDD|179076
NC_004432.1|WP_011077828.1|1328231_1329071_-|50S-ribosomal-protein-L2	unknown	unknown	gnl|CDD|236488
NC_004432.1|WP_011077834.1|1332545_1333313_-|type-III-pantothenate-kinase	unknown	unknown	gnl|CDD|367441
NC_004432.1|WP_011077839.1|1340595_1341129_-|hypoxanthine-phosphoribosyltransferase	unknown	unknown	gnl|CDD|223707
NC_004432.1|WP_011077830.1|1329521_1330163_-|50S-ribosomal-protein-L4	unknown	unknown	gnl|CDD|235404
NC_004432.1|WP_011077826.1|1326897_1327923_-|50S-ribosomal-protein-L22	unknown	unknown	gnl|CDD|138835
NC_004432.1|WP_044891322.1|1327940_1328219_-|30S-ribosomal-protein-S19	unknown	unknown	gnl|CDD|178985
NC_004432.1|WP_011077821.1|1323782_1324151_-|50S-ribosomal-protein-L14	unknown	unknown	gnl|CDD|180117
NC_004432.1|WP_011077838.1|1338073_1340542_-|ATP-dependent-metallopeptidase-FtsH/Yme1/Tma-family-protein	unknown	unknown	gnl|CDD|273520
NC_004432.1|WP_011077836.1|1334046_1334565_-|adenine-phosphoribosyltransferase	unknown	unknown	gnl|CDD|235028

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_004432.1|WP_011077825.1|1326452_1326875_-|50S-ribosomal-protein-L16	gnl|CDD|236411	PRK09203, rplP, 50S ribosomal protein L16; Reviewed.	7.80888e-78
NC_004432.1|WP_011077829.1|1329105_1329522_-|50S-ribosomal-protein-L23	gnl|CDD|237035	PRK12280, rplW, 50S ribosomal protein L23; Reviewed.	1.01429e-32
NC_004432.1|WP_044891325.1|1341771_1342620_-|ABC-transporter-ATP-binding-protein	gnl|CDD|224059	COG1136, SalX, ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms].	3.84691e-90
NC_004432.1|WP_011077837.1|1334574_1337958_-|preprotein-translocase-subunit-SecD	gnl|CDD|237276	PRK13024, PRK13024, bifunctional preprotein translocase subunit SecD/SecF; Reviewed.	6.54062e-26
NC_004432.1|WP_011077833.1|1331693_1332524_-|Cof-type-HAD-IIB-family-hydrolase	gnl|CDD|369792	pfam08282, Hydrolase_3, haloacid dehalogenase-like hydrolase. This family contains haloacid dehalogenase-like hydrolase enzymes.	8.29629e-61
NC_004432.1|WP_044891324.1|1341226_1341685_-|2-C-methyl-D-erythritol-2,4-cyclodiphosphate-synthase	gnl|CDD|178851	PRK00084, ispF, 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase; Reviewed.	8.97625e-57
NC_004432.1|WP_052270432.1|1325731_1326460_-|50S-ribosomal-protein-L29	gnl|CDD|238243	cd00427, Ribosomal_L29_HIP, Ribosomal L29 protein/HIP. L29 is a protein of the large ribosomal Subunit. A homolog, called heparin/heparan sulfate interacting protein (HIP), has also been identified in mammals. L29 is located on the surface of the large ribosomal subunit, where it participates in forming a protein ring that surrounds the polypeptide exit channel, providing structural support for the ribosome. L29 is involved in forming the translocon binding site, along with L19, L22, L23, L24, and L31e. In addition, L29 and L23 form the interaction site for trigger factor (TF) on the ribosomal surface, adjacent to the exit tunnel. L29 forms numerous interactions with L23 and with the 23S rRNA. In some eukaryotes, L29 is referred to as L35, which is distinct from L35 found in bacteria and some eukaryotes (primarily plastids and mitochondria). The mammalian homolog, HIP, is found on the surface of many tissues and cell lines. It is believed to play a role in cell adhesion and modulation of blood coagulation. It has also been shown to inhibit apoptosis in cancer cells.	4.90725e-13
NC_004432.1|WP_011077823.1|1324475_1325729_-|30S-ribosomal-protein-S3	gnl|CDD|234722	PRK00310, rpsC, 30S ribosomal protein S3; Reviewed.	9.53228e-106
NC_004432.1|WP_011077822.1|1324181_1324457_-|30S-ribosomal-protein-S17	gnl|CDD|235532	PRK05610, rpsQ, 30S ribosomal protein S17; Reviewed.	1.74461e-39
NC_004432.1|WP_044891436.1|1333336_1333960_-|ribonuclease-HII	gnl|CDD|260003	cd07182, RNase_HII_bacteria_HII_like, Bacterial Ribonuclease HII-like. This family includes mostly bacterial type 2 RNases H, with some eukaryotic members. Bacterial RNase HII has a role in primer removal based on its involvement in ribonucleotide-specific catalytic activity in the presence of RNA/DNA hybrid substrates. Several bacteria, such as Bacillus subtilis, have two different type II RNases H, RNases HII and HIII; double deletion of these leads to cellular lethality. It appears that type I and type II RNases H also have overlapping functions in cells, as over-expression of Escherichia coli RNase HII can complement an RNase HI deletion phenotype. In Leishmania mitochondria, of the four distinct RNase H genes (H1, HIIA, HIIB, HIIC), HIIC is essential for the survival of the parasite and thus can be a potential target for anti-leishmanial chemotherapy. Ribonuclease H (RNase H) is classified into two families, type I (prokaryotic RNase HI, eukaryotic RNase H1 and viral RNase H) and type II (prokaryotic RNase HII and HIII, and eukaryotic RNase H2). RNase H endonucleolytically hydrolyzes an RNA strand when it is annealed to a complementary DNA strand in the presence of divalent cations, in DNA replication and repair.	2.07477e-77
NC_004432.1|WP_044891323.1|1331114_1331423_-|30S-ribosomal-protein-S10	gnl|CDD|179076	PRK00596, rpsJ, 30S ribosomal protein S10; Reviewed.	4.96433e-52
NC_004432.1|WP_011077828.1|1328231_1329071_-|50S-ribosomal-protein-L2	gnl|CDD|236488	PRK09374, rplB, 50S ribosomal protein L2; Validated.	3.31261e-169
NC_004432.1|WP_011077834.1|1332545_1333313_-|type-III-pantothenate-kinase	gnl|CDD|367441	pfam03309, Pan_kinase, Type III pantothenate kinase. Type III pantothenate kinase catalyzes the phosphorylation of pantothenate (Pan), the first step in the universal pathway of CoA biosynthesis.	1.69893e-34
NC_004432.1|WP_011077839.1|1340595_1341129_-|hypoxanthine-phosphoribosyltransferase	gnl|CDD|223707	COG0634, Hpt, Hypoxanthine-guanine phosphoribosyltransferase [Nucleotide transport and metabolism].	5.93319e-69
NC_004432.1|WP_011077830.1|1329521_1330163_-|50S-ribosomal-protein-L4	gnl|CDD|235404	PRK05319, rplD, 50S ribosomal protein L4; Provisional.	7.77228e-74
NC_004432.1|WP_011077826.1|1326897_1327923_-|50S-ribosomal-protein-L22	gnl|CDD|138835	PRK12279, PRK12279, 50S ribosomal protein L22/unknown domain fusion protein; Provisional.	2.02684e-162
NC_004432.1|WP_044891322.1|1327940_1328219_-|30S-ribosomal-protein-S19	gnl|CDD|178985	PRK00357, rpsS, 30S ribosomal protein S19; Reviewed.	5.20948e-53
NC_004432.1|WP_011077821.1|1323782_1324151_-|50S-ribosomal-protein-L14	gnl|CDD|180117	PRK05483, rplN, 50S ribosomal protein L14; Validated.	7.86577e-73
NC_004432.1|WP_011077838.1|1338073_1340542_-|ATP-dependent-metallopeptidase-FtsH/Yme1/Tma-family-protein	gnl|CDD|273520	TIGR01241, ATP-dependent_zinc_metalloprotease_FtsH, ATP-dependent metalloprotease FtsH. HflB(FtsH) is a pleiotropic protein required for correct cell division in bacteria. It has ATP-dependent zinc metalloprotease activity. It was formerly designated cell division protein FtsH. [Cellular processes, Cell division, Protein fate, Degradation of proteins, peptides, and glycopeptides].	0
NC_004432.1|WP_011077836.1|1334046_1334565_-|adenine-phosphoribosyltransferase	gnl|CDD|235028	PRK02304, PRK02304, adenine phosphoribosyltransferase; Provisional.	1.34428e-79

Protein sequences

>NC_004432.1|WP_011077830.1|1329521_1330163_-|50S-ribosomal-protein-L4
MSSVKLFKDLLGNTETVELKNKKLFISDKKINHQEIFNSVLVEEANSRQSTASTLTKAEVRGGGRKPYKQKHTGRARQGSIRNPHYVGGGRAFGPSPEKNYTLKQNSKAYKLAFQSAMTLKLNEQGLNLLVNKIDMKEPSTKTISKMLKKVSYENKKVLFVINDKNENFLKSCKNIQKVTSKMWNQVSVRDILNSDIAVIQEDAFDKISEVFA
>NC_004432.1|WP_011077829.1|1329105_1329522_-|50S-ribosomal-protein-L23
MDLLSVIIKPLHSEKSYSLRNEDIKKYVFEVNRNANKYEISLAFQLIYGIVPNKVNVVNRKPTPTRTGTRNPGMTKAKKIAYITLPHGVDIQIDEEPSKEKPKKENKKELVTERKEEKKEKPKKGVLSKLVKTSPKAK
>NC_004432.1|WP_011077828.1|1328231_1329071_-|50S-ribosomal-protein-L2
MPIRRVKARSSGIRQTVIIDYKKVLTTSTPEKSLVVSLKKHSGRNNNGKITVRHHGGGYKKKYRIIDFKRDKINKVATVKSIEYDPNRTSFISLVVYEDGEKRYIIAPKDLKIGDRILSSNKQIDIKVGNALPISLIPEGTFVHNIELYPGRGGQMIRSAGSSAQILGKDETGEYTIVKLSSGEVRKIANGCMATIGVVSNEDHNLVVIGKAGTNRHRGIRPTVRGSAMNPNDHPHGGGEGRSPVGHDAPRTPWGKRHMGVKTRNKKKQSNALIIRRKK
>NC_004432.1|WP_044891322.1|1327940_1328219_-|30S-ribosomal-protein-S19
MSRSSKKGPYIEPSLMKKVQAMKAADKKKPIKTWSRRSTIFPDFVGLNFEVHNGKSFVNVYVTEDMIGHKLGEFAQTRTFKQHTSNRKDLAK
>NC_004432.1|WP_011077826.1|1326897_1327923_-|50S-ribosomal-protein-L22
MQARAIQKNIHVSPRKAKLVCDLIRNKPVTNALSILENTNKKTAVFLKKLLHQAIANATNNHAMQADKLYVYHVVANQGSTLKRTSPRAKGSADLIRKRHTHLEIVLSDDVNERNKEIQAIKDRIKKRAANNKGYWAKQRAANEAGLKVVEKPKKAKPAQPKKPVEKKPQPKPEPKVVKEEPVKPVKAESLKREQEVLKVVETKPVEGAKKAKVEETAIIMISTKKEYADNLLNEELNKNVFFYKVTPVNPIKRVLIYTTTGKKGVVGEFDLDKIEILALSTAWKKYGQQSCMSKKDFDEYYKDSEKAHILISKEAFRYSRPKTLESYNMKKGPSGFQYLK
>NC_004432.1|WP_011077825.1|1326452_1326875_-|50S-ribosomal-protein-L16
MLEPKRTKYRRPHKVSYEGKAKGNKYVAFGEFGLMATNGAWISNRQIESARIAISKALGKTGKMWIRIFPHLSLTKKPLEVRMGSGKGSPEKWVAVVKAGTVMFEVANIPEEVARTALKNAGNKLSVNWKIVKKGEIAHD
>NC_004432.1|WP_052270432.1|1325731_1326460_-|50S-ribosomal-protein-L29
MIKELRTKTDNELGNLISKLKIQLLEMRFKIANGEVEGLHKFKEIKKTIAMAMTVLSERNVKISFSTFSTQLIKQKNGKQEIVSLSIVDERKDAVKSQPKAKPVEANKPAVSESKKEEPKKVETNNKPVAKPVVKKEQPVQSKPAAKPTAKPVAKPVAKTTASNSKPATSKPVSKPTGKPVAKPAASNSKPVASKPMAKPAAKPTGKPVAKPAAKPAASNSKPTTSKPASKTTAKAPVKGKK
>NC_004432.1|WP_011077823.1|1324475_1325729_-|30S-ribosomal-protein-S3
MGQKVNPNGLRLGINRNWESRWVAKDNRQTALWLVQDDKIRKHIFKVCKAAQVSHVEIERTQNKVDIFIHCSQPGIVLGKEMSNLKVLKQQLSYIVGRKTKVNVNVLPLDKPTFSARIIAREIADAIENRFSFRNAQKIAIKKVLASGAKGIKTNVSGRLGGVEMAREEGYSEGIVPLTTLRANIDYALEEAWTTYGLIGVKVWINRGELFKKNFSQNTKFEKKPIEKKREQQPVQQQKPQQPKPQPKVVKEVKQEEPAKPVKAESLKREQEVLKVVEAKPAEGAKKGKVEETAIIMISTKKEYADNLLNEDLNKNVFFYKVTPVNPIKRVLIYTTTGKKGVVGEFDLDKIEILAVSTAWRKYGQQSCMSKKDFDEYYKDSEKAHILISKEAFRYSRPKTLESYNMKKGPSGFQYLK
>NC_004432.1|WP_011077822.1|1324181_1324457_-|30S-ribosomal-protein-S17
MSSQVNTTRDSRRKILQGIVVSDKMQKTIVVQVERKSKHRLYKKLVITHKKYHAHDEKEECKIGDFVEIMETRPLSATKRWRLNKIIQKAK
>NC_004432.1|WP_011077821.1|1323782_1324151_-|50S-ribosomal-protein-L14
MIQFMTKLNVADNTGAKQVGVIKVLGGTKRRYASVGDIVVVSVKKAQPDGIVRKGQVCKAVIVRVKKNITRSSGNSLSFDDNACVIIKEDKTPRGSRIFGPVARELRDKGFSKIVSLAPEVL
>NC_004432.1|WP_044891323.1|1331114_1331423_-|30S-ribosomal-protein-S10
MKNEMKIKLFSYDHRLLDQSVRKIIKSSQDSGAKVKGPIPLPTKKEIFTICRSPHVNKTSREQFERRTHQRLIILLNTTEKTKEYLKNIIIPSGVDIQITLR
>NC_004432.1|WP_011077833.1|1331693_1332524_-|Cof-type-HAD-IIB-family-hydrolase
MYTKCIYFDIDGTLVPDGVTLTNKTIMAIRYLKDKNIKIGLATGRNIFFAEYFAKVLDVDMPLVCVNGAWIVTPKDYLNISTKYIDFKPQLQLLDVLYKEKKDFLVYTIDGVYSTSENQPFYKRLLSVQEKLKEKKIKSRLVYEMKVNPNLVFYSKQKLLKVLICYDNVSEKIKYENILSNIPNLAFSVSQNGIIDIYNGEVDKANGIEYAINNFRINKREVMVFGDNDNDLNMMKTFKMSVALKNADYQIRKAATYTTDFTCEEEGVADFIFKHF
>NC_004432.1|WP_011077834.1|1332545_1333313_-|type-III-pantothenate-kinase
MKNNQEYILVVDIGNSYTKIGIFEKEKENTTSIILFPTDSETNIATLSKKMNVFKKYNIKHSIVGSVVPKLKPTYFKTIKKMFNIEPYYISETTKYSFLIDESPNKELGDDLKALCEYCVSVNKNCIGISFGTAIASVYLKNNSLVGASIAAGLGFGLNKLIEKASLLKKSKIDKFSSDFFGTNTISALESGINNLRSGFAYNFYNQAKKDNLNSDLKCIITGGESYNINISSFEYEINKEAILLGFKKIYFLNN
>NC_004432.1|WP_044891436.1|1333336_1333960_-|ribonuclease-HII
MKNKLFDFDNSLREKYKNIIGLDEVGRGCIAGPLVVVGVILNPNFFDDRIKDSKLIKSIELRKELKNLILKNSISYQIEVVNSNIVDQLGPKQASVKGMTKIANGLINDYDLCLTDFEKIKDLEKPQMNLVKGDNTSFTIACASIIAKSTRDDYMEELDNKYPNYLFKNHQGYLTKKHLQLIHQYGPIKEVHRFSYKPIKLILNKSK
>NC_004432.1|WP_011077836.1|1334046_1334565_-|adenine-phosphoribosyltransferase
MGYEEIKNTIATIEDFPKKGISFKDITPLLLDHKKMNFIIDELAKFAKTIDFDIIVAPESRGFLFGLPLALNLKKPFVPIRKKGKLPREVISQEYELEYGKATIEVTKNDIPANSKVLIIDDLIATGGTTVAIQDLVTKLGSTVVGQAYLIELVGLCDYEKLQGKFFSMIKY
>NC_004432.1|WP_011077837.1|1334574_1337958_-|preprotein-translocase-subunit-SecD
MAFEKIKNGFNNFFGSVKLGFYNFFKSFNFASRSKGSKVFKSLFFFFLCAGSIVGVVFGLINLGENNRSQGLFGNTYNSSYRLDVSSATSESQAKDLASKAAEKFSNYLSYNNVKTNNINYEVKSGSNNGYEAYLYVSYSNVSLYYDDNFKNSSTGGYYEIDPNIYGINNARSNTVSAYYFNPQGTTPQDVFTFNNTRSGSGTNSRRSQVFTTSDFDYSSATIDTRKSGENSDNLNNYGINLKLTGSSYEYLNDAGLDASNSLSFASQSSSSSDDAGSTATANSDLQWIVVKDIDQLVNLLNYAKWVVLNYNNYRGNTSVSGGTQTKWMVYYDYLNSTNSSLVTWAEKAVNWTTNKTTVSAITPEYLIAAYEYALDHLNSSVKSTISNSSNFPEIQYDGDSSLIEVMKNYVIGVVSKVNYKQWFPSVTSTTTGLSGVSVTNFSIQPSAYQSSSYTSTASSDSSTSTSSLTVNTQATGDVSTAADTTTTTTTTGTTTRESLRSSYISSFKNLAFPTTFYSATPTSRNSSGWITSSNLPTMNLSYEVSNGTTSSNNNQITDSNNSLVNSNRNTTNYFGLNSWVSSPLIEQSIIDKISTYNSVFLASGVILLLVAIIVSVWYRIPGVMAAFAIIISFGFSISLLAVFQIDISISSILGLFIGVISSVMAASITMERMRRLVLQKNSVFDSIHIAIKKSMLTIIDLNITLIILGLSMFFIAKGELTDMGITMLLSSVFSLVVSFIFFLLPLYTYSGFKFSWSFKRNIWHINTNFKHKIHFSSKGWWIVWGVLIGVVVLSGIIFAVVGPNNSVYKNGSFVSMTVLGHTNSSVVDTNALFNAIKNALGSSWNLTFKNTSDYLSAVTGSNLQAQGYYYVVIQGYSQNSYSLETVQNLVRNALNGFYSSTTNSSSLINGIVNNVTLSSVSPAVLNTLVLRAVYALLAGYGFLAIYYAIRLNILTVLPVLLTSMLSTSVVVGVSYLVQFEINNLFVYVIAMSGIMSALFSCLYVSVTKTRFVKRRIFDGEKIQNFILNNLCSLYNVVYVTLIANVVIFALLAGLISPTIILLFINILIANAVAIPLGFFLIAHLYYYVILIRQKYVRTIVDNFDNRIRNEFKETDEQLIIGINKFY
>NC_004432.1|WP_011077838.1|1338073_1340542_-|ATP-dependent-metallopeptidase-FtsH/Yme1/Tma-family-protein
MEFNKLELLIIRALKLNTNSNKKNSFYNKFLNLRNKVLNIQKNSLDQPSDAPSNNKKRNLDQPDNPNQKEPGKARKIIWSFIIIILVLGVLALIILSGFSFSATSLNAASFTENGTSSFKITTNTNQTRTIGGAPSTIYQRDSTLYVIYIENSFSGYYYSAIITDISVSNNTASVGNGSNTTGGSTSNLQKGLQIANLLVDGSGNVYKNKDNNGSTTSGTTTFSLNSNLTSAMKLQGWSSNQSMSLPTSYSFYTAASLVLSILPFILLIGIIYYSMRKMGQAGGGQDNVFSIGKSQAKLAKSTVLFSDVAGIEEEKEELIEIVDYLKRPDRYAAMGARVPKGVILYGPPGTGKTLLAKAVAGEAKVPFFQVSGSAFEDMLVGVGAKRVRDLFNKAVKSAPAIIFIDEIDSVGSKRGKFETTAGSLADQTLNQLLAEMDGFNTKTGVIVMAATNRLDVLDDALLRPGRFDRHIQVNLPDIKERVAILKIHSRNKNISETVDLEDIARRTPGFSGAQLENVLNEATLLAVRRNKKSIYTEELDEAIDRVIAGPAKKTRVISLEEKRQIAFHEAGHAIVGMYTKGSEVVEKITIIPRGQAAGYTLSVPEIQELSIQKKSDLLGMVAGLLGGRASEEINFGKEFISTGAANDLYKATNIVRAMVTQFGMSPNVGLAQYYPSEGTVNPYQSKNFSESTSQLIDKEIERIFKERYEYAYKIIKEHNKEVELIVESLLLLETIVKPQIDFIHKYKQLPKEALEKKKELEEKKKAEDLIRKAKKESEASSKEEKEMDVEKKVQKPSASSTEPTSKPKKAPSKESSSDKKK
>NC_004432.1|WP_011077839.1|1340595_1341129_-|hypoxanthine-phosphoribosyltransferase
MDHRVEKILLTTEEIQKGIIEAAKWVDKTYQNKELVLVGLLKGCLPFFGQMISHITIDCLVDFMTVSSFQGKTYGVTEPQISHNISENITNKHVLLVDEIIDSALTLKYVKEYLMNNFNPASVEIITLLDKPAGRKVDLKPAYRCFEIENKFVVGYGCDYEGKLRNLPYVGVFKQDK
>NC_004432.1|WP_044891324.1|1341226_1341685_-|2-C-methyl-D-erythritol-2,4-cyclodiphosphate-synthase
MKYKIGNGIDIHKIKKEKCKQRLAGLDFELDYKIIAHSDGDIILHSISSAILGALSLQDLGTYFSDTDSKNKNLDSLEILSMCLNELKKQDYSISNVDITIICEYIIFKDIKDQIKSNLEKLLNNTEISLKATRYEEDKNMIQVNTVLLINK
>NC_004432.1|WP_044891325.1|1341771_1342620_-|ABC-transporter-ATP-binding-protein
MLEKNNQVKQKISVSEKKKNKLLKKQNSKIHKEIKRLNKPHDGPIEKKNTEGYIFELTDVTKKFSNGYLVNDVLKGINLKIKQGKFVVILGKSGSGKTTLMNILSALTRATTGSVVVNNHELINMKNNDLTNFRRKYVGYIFQEYGLLATLNVYDNILTGFNLNKENRDKKEIDEIIKLVELEQHKNKFPSELSGGQQQRVSIARAVAKKPLIIFGDEPTGAVDSSMSKKILQILKSVNKKYKTTIVLITHDKEIAKIADQVIVIKNGLIEEIIENPNPLEP

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NC_004432_2	2.1|721199|31|NC_004432|CRISPRCasFinder	721199-721229	31	NC_031065	Salmonella phage vB_SnwM_CGG4-1, complete genome	565-595	6	0.806
NC_004432_2	2.1|721199|31|NC_004432|CRISPRCasFinder	721199-721229	31	KJ000058	Salmonella phage STP4-a, complete genome	556-586	6	0.806
NC_004432_2	2.1|721199|31|NC_004432|CRISPRCasFinder	721199-721229	31	AP013647	Uncultured Mediterranean phage uvMED isolate uvMED-CGF-C72-MedDCM-OCT-S41-C96, *** SEQUENCING IN PROGRESS ***	11457-11487	6	0.806
NC_004432_1	1.1|664264|32|NC_004432|CRISPRCasFinder	664264-664295	32	AP014611	Serratia marcescens plasmid p11663 DNA, complete sequence, strain: 11663	148291-148322	7	0.781
NC_004432_1	1.1|664264|32|NC_004432|CRISPRCasFinder	664264-664295	32	NZ_CP038624	Arsenophonus nasoniae strain FIN plasmid pArsFIN12, complete sequence	9005-9036	7	0.781
NC_004432_1	1.1|664264|32|NC_004432|CRISPRCasFinder	664264-664295	32	NZ_CP017208	Borreliella burgdorferi strain B331 plasmid B331_cp32_6, complete sequence	11520-11551	7	0.781
NC_004432_1	1.1|664264|32|NC_004432|CRISPRCasFinder	664264-664295	32	MF417891	Uncultured Caudovirales phage clone 10S_13, partial genome	4466-4497	7	0.781
NC_004432_2	2.1|721199|31|NC_004432|CRISPRCasFinder	721199-721229	31	HQ331142	Salmonella phage S16, complete genome	565-595	7	0.774
NC_004432_1	1.1|664264|32|NC_004432|CRISPRCasFinder	664264-664295	32	CP003185	Thermoanaerobacterium saccharolyticum JW/SL-YS485 plasmid pMU3262, complete genome	21028-21059	8	0.75
NC_004432_1	1.1|664264|32|NC_004432|CRISPRCasFinder	664264-664295	32	NC_019956	Thermoanaerobacterium thermosaccharolyticum M0795 plasmid pTHETHE01, complete sequence	81257-81288	8	0.75
NC_004432_1	1.1|664264|32|NC_004432|CRISPRCasFinder	664264-664295	32	NC_017394	Borreliella burgdorferi JD1 plasmid JD1 cp32-1+5, complete sequence	11530-11561	8	0.75
NC_004432_1	1.1|664264|32|NC_004432|CRISPRCasFinder	664264-664295	32	NC_017394	Borreliella burgdorferi JD1 plasmid JD1 cp32-1+5, complete sequence	42253-42284	8	0.75
NC_004432_1	1.1|664264|32|NC_004432|CRISPRCasFinder	664264-664295	32	NZ_MK275627	Clostridium perfringens strain JXJA17 plasmid p9, complete sequence	2444-2475	8	0.75
NC_004432_1	1.1|664264|32|NC_004432|CRISPRCasFinder	664264-664295	32	NZ_CP017574	Bacillus thuringiensis strain SCG04-02 plasmid PSCG364, complete sequence	100011-100042	8	0.75
NC_004432_1	1.1|664264|32|NC_004432|CRISPRCasFinder	664264-664295	32	NC_014172	Bacillus thuringiensis BMB171 plasmid pBMB171, complete sequence	153758-153789	8	0.75
NC_004432_1	1.1|664264|32|NC_004432|CRISPRCasFinder	664264-664295	32	NZ_CP019918	Borreliella burgdorferi strain PAbe plasmid p_cp32-5-1, complete sequence	4879-4910	8	0.75
NC_004432_1	1.1|664264|32|NC_004432|CRISPRCasFinder	664264-664295	32	NZ_CP019918	Borreliella burgdorferi strain PAbe plasmid p_cp32-5-1, complete sequence	35557-35588	8	0.75
NC_004432_1	1.1|664264|32|NC_004432|CRISPRCasFinder	664264-664295	32	NZ_CP019919	Borreliella burgdorferi strain PAbe plasmid p_cp32-2, complete sequence	11517-11548	8	0.75
NC_004432_1	1.1|664264|32|NC_004432|CRISPRCasFinder	664264-664295	32	NZ_CP019920	Borreliella burgdorferi strain PAbe plasmid p_cp32-3, complete sequence	7164-7195	8	0.75
NC_004432_1	1.1|664264|32|NC_004432|CRISPRCasFinder	664264-664295	32	NZ_CP019921	Borreliella burgdorferi strain PAbe plasmid p_cp32-9-4, complete sequence	11687-11718	8	0.75
NC_004432_1	1.1|664264|32|NC_004432|CRISPRCasFinder	664264-664295	32	NZ_CP019921	Borreliella burgdorferi strain PAbe plasmid p_cp32-9-4, complete sequence	42200-42231	8	0.75
NC_004432_1	1.1|664264|32|NC_004432|CRISPRCasFinder	664264-664295	32	NZ_CP019926	Borreliella burgdorferi strain PAbe plasmid p_lp56, complete sequence	15088-15119	8	0.75
NC_004432_1	1.1|664264|32|NC_004432|CRISPRCasFinder	664264-664295	32	NZ_CP009595	Bacillus cereus strain 3a plasmid pBFC_3, complete sequence	35700-35731	8	0.75
NC_004432_1	1.1|664264|32|NC_004432|CRISPRCasFinder	664264-664295	32	NZ_CP009606	Bacillus cereus strain S2-8 plasmid pBFR_2, complete sequence	214413-214444	8	0.75
NC_004432_1	1.1|664264|32|NC_004432|CRISPRCasFinder	664264-664295	32	NC_018982	Borrelia burgdorferi 297 plasmid 297_cp32-9, complete sequence	3319-3350	8	0.75
NC_004432_1	1.1|664264|32|NC_004432|CRISPRCasFinder	664264-664295	32	NC_017398	Borreliella burgdorferi N40 plasmid N40_cp32-5, complete sequence	7070-7101	8	0.75
NC_004432_1	1.1|664264|32|NC_004432|CRISPRCasFinder	664264-664295	32	NZ_CP016746	Lactococcus lactis subsp. cremoris strain JM1 plasmid pMPJM1, complete sequence	141161-141192	8	0.75
NC_004432_1	1.1|664264|32|NC_004432|CRISPRCasFinder	664264-664295	32	NC_011722	Borreliella burgdorferi ZS7 plasmid ZS7_cp32-9, complete sequence	11634-11665	8	0.75
NC_004432_1	1.1|664264|32|NC_004432|CRISPRCasFinder	664264-664295	32	NC_000948	Borreliella burgdorferi B31 plasmid cp32-1, complete sequence	11598-11629	8	0.75
NC_004432_1	1.1|664264|32|NC_004432|CRISPRCasFinder	664264-664295	32	NC_000949	Borreliella burgdorferi B31 plasmid cp32-3, complete sequence	11598-11629	8	0.75
NC_004432_1	1.1|664264|32|NC_004432|CRISPRCasFinder	664264-664295	32	NC_000951	Borreliella burgdorferi B31 plasmid cp32-6, complete sequence	11608-11639	8	0.75
NC_004432_1	1.1|664264|32|NC_004432|CRISPRCasFinder	664264-664295	32	NC_000953	Borreliella burgdorferi B31 plasmid cp32-8, complete sequence	11598-11629	8	0.75
NC_004432_1	1.1|664264|32|NC_004432|CRISPRCasFinder	664264-664295	32	NC_000954	Borreliella burgdorferi B31 plasmid cp32-9, complete sequence	11687-11718	8	0.75
NC_004432_1	1.1|664264|32|NC_004432|CRISPRCasFinder	664264-664295	32	NC_000956	Borreliella burgdorferi B31 plasmid lp56, complete sequence	15088-15119	8	0.75
NC_004432_1	1.1|664264|32|NC_004432|CRISPRCasFinder	664264-664295	32	NZ_CP015800	Borrelia mayonii strain MN14-1539 plasmid cp32-3, complete sequence	11520-11551	8	0.75
NC_004432_1	1.1|664264|32|NC_004432|CRISPRCasFinder	664264-664295	32	NZ_CP019846	Borreliella burgdorferi plasmid cp32-1, complete sequence	11581-11612	8	0.75
NC_004432_1	1.1|664264|32|NC_004432|CRISPRCasFinder	664264-664295	32	NZ_CP019847	Borreliella burgdorferi plasmid cp32-3, complete sequence	11598-11629	8	0.75
NC_004432_1	1.1|664264|32|NC_004432|CRISPRCasFinder	664264-664295	32	NZ_CP019848	Borreliella burgdorferi plasmid cp32-4, complete sequence	11542-11573	8	0.75
NC_004432_1	1.1|664264|32|NC_004432|CRISPRCasFinder	664264-664295	32	NZ_CP019849	Borreliella burgdorferi plasmid cp32-5, complete sequence	11594-11625	8	0.75
NC_004432_1	1.1|664264|32|NC_004432|CRISPRCasFinder	664264-664295	32	NZ_CP019850	Borreliella burgdorferi plasmid cp32-9, complete sequence	11616-11647	8	0.75
NC_004432_1	1.1|664264|32|NC_004432|CRISPRCasFinder	664264-664295	32	NZ_CP019855	Borreliella burgdorferi plasmid lp56, complete sequence	15088-15119	8	0.75
NC_004432_1	1.1|664264|32|NC_004432|CRISPRCasFinder	664264-664295	32	NZ_CP019756	Borreliella burgdorferi strain B31_NRZ isolate B31 plasmid p_cp32-1_1, complete sequence	11595-11626	8	0.75
NC_004432_1	1.1|664264|32|NC_004432|CRISPRCasFinder	664264-664295	32	NZ_CP019756	Borreliella burgdorferi strain B31_NRZ isolate B31 plasmid p_cp32-1_1, complete sequence	42273-42304	8	0.75
NC_004432_1	1.1|664264|32|NC_004432|CRISPRCasFinder	664264-664295	32	NZ_CP019757	Borreliella burgdorferi strain B31_NRZ isolate B31 plasmid p_cp32-2, complete sequence	11517-11548	8	0.75
NC_004432_1	1.1|664264|32|NC_004432|CRISPRCasFinder	664264-664295	32	NZ_CP019758	Borreliella burgdorferi strain B31_NRZ isolate B31 plasmid p_cp32-3, complete sequence	11598-11629	8	0.75
NC_004432_1	1.1|664264|32|NC_004432|CRISPRCasFinder	664264-664295	32	NZ_CP019759	Borreliella burgdorferi strain B31_NRZ isolate B31 plasmid p_cp32-4, complete sequence	11543-11574	8	0.75
NC_004432_1	1.1|664264|32|NC_004432|CRISPRCasFinder	664264-664295	32	NZ_CP019760	Borreliella burgdorferi strain B31_NRZ isolate B31 plasmid p_cp32-9, complete sequence	11687-11718	8	0.75
NC_004432_1	1.1|664264|32|NC_004432|CRISPRCasFinder	664264-664295	32	NZ_CP019766	Borreliella burgdorferi strain B31_NRZ isolate B31 plasmid p_lp56, complete sequence	15068-15099	8	0.75
NC_004432_1	1.1|664264|32|NC_004432|CRISPRCasFinder	664264-664295	32	NZ_CP053994	Bacillus cereus strain FDAARGOS_780 plasmid unnamed1, complete sequence	288184-288215	8	0.75
NC_004432_1	1.1|664264|32|NC_004432|CRISPRCasFinder	664264-664295	32	NZ_CP043831	Bacillus sp. BS98 plasmid unnamed1	58365-58396	8	0.75
NC_004432_1	1.1|664264|32|NC_004432|CRISPRCasFinder	664264-664295	32	NC_004971	Borrelia burgdorferi 297 plasmid cp18-2, complete sequence	3302-3333	8	0.75
NC_004432_1	1.1|664264|32|NC_004432|CRISPRCasFinder	664264-664295	32	NC_011731	Borreliella burgdorferi ZS7 plasmid ZS7_cp32-1, complete sequence	11513-11544	8	0.75
NC_004432_1	1.1|664264|32|NC_004432|CRISPRCasFinder	664264-664295	32	NC_011735	Borreliella burgdorferi ZS7 plasmid ZS7_cp32-12, complete sequence	11513-11544	8	0.75
NC_004432_1	1.1|664264|32|NC_004432|CRISPRCasFinder	664264-664295	32	NZ_CP017203	Borreliella burgdorferi strain B331 plasmid B331_cp32_1, complete sequence	11606-11637	8	0.75
NC_004432_1	1.1|664264|32|NC_004432|CRISPRCasFinder	664264-664295	32	NZ_CP017205	Borreliella burgdorferi strain B331 plasmid B331_cp32_11, complete sequence	11607-11638	8	0.75
NC_004432_1	1.1|664264|32|NC_004432|CRISPRCasFinder	664264-664295	32	NZ_CP017206	Borreliella burgdorferi strain B331 plasmid B331_cp32_4, complete sequence	11611-11642	8	0.75
NC_004432_1	1.1|664264|32|NC_004432|CRISPRCasFinder	664264-664295	32	NZ_CP015784	Borrelia mayonii strain MN14-1420 plasmid cp32-3, complete sequence	11520-11551	8	0.75
NC_004432_1	1.1|664264|32|NC_004432|CRISPRCasFinder	664264-664295	32	NZ_CP009368	Bacillus cereus strain FM1 plasmid unnamed, complete sequence	261831-261862	8	0.75
NC_004432_1	1.1|664264|32|NC_004432|CRISPRCasFinder	664264-664295	32	NZ_CP009336	Bacillus thuringiensis strain HD1011 plasmid 1, complete sequence	49818-49849	8	0.75
NC_004432_1	1.1|664264|32|NC_004432|CRISPRCasFinder	664264-664295	32	NZ_CP053992	Bacillus cereus strain FDAARGOS_781 plasmid unnamed2, complete sequence	271200-271231	8	0.75
NC_004432_2	2.1|721199|31|NC_004432|CRISPRCasFinder	721199-721229	31	JX181825	Salmonella phage STML-198, complete genome	42737-42767	8	0.742
NC_004432_2	2.1|721199|31|NC_004432|CRISPRCasFinder	721199-721229	31	NC_042044	Salmonella phage Melville, complete genome	556-586	8	0.742
NC_004432_2	2.1|721199|31|NC_004432|CRISPRCasFinder	721199-721229	31	KX961632	Bacillus phage SBP8a, complete genome	155922-155952	8	0.742
NC_004432_2	2.1|721199|31|NC_004432|CRISPRCasFinder	721199-721229	31	NC_029073	Geobacillus virus E3, complete genome	95643-95673	8	0.742
NC_004432_1	1.1|664264|32|NC_004432|CRISPRCasFinder	664264-664295	32	NZ_CP024184	Moraxella osloensis strain KSH plasmid p4, complete sequence	38213-38244	9	0.719
NC_004432_1	1.1|664264|32|NC_004432|CRISPRCasFinder	664264-664295	32	NC_019700	Oscillatoria acuminata PCC 6304 plasmid pOSCIL6304.01, complete sequence	10331-10362	9	0.719
NC_004432_1	1.1|664264|32|NC_004432|CRISPRCasFinder	664264-664295	32	NZ_CP024445	Moraxella osloensis strain NP7 plasmid pNP7-2, complete sequence	84097-84128	9	0.719
NC_004432_1	1.1|664264|32|NC_004432|CRISPRCasFinder	664264-664295	32	NC_015708	Pseudoalteromonas sp. SANK 73390 plasmid pTML1 carrying thiomarinol biosynthesis cluster	46938-46969	9	0.719
NC_004432_1	1.1|664264|32|NC_004432|CRISPRCasFinder	664264-664295	32	NC_021325	Clostridium phage vB_CpeS-CP51, complete genome	28666-28697	9	0.719
NC_004432_1	1.1|664264|32|NC_004432|CRISPRCasFinder	664264-664295	32	NC_048074	Acinetobacter phage vB_AbaM_B09_Aci01-1, complete genome	55427-55458	9	0.719
NC_004432_2	2.1|721199|31|NC_004432|CRISPRCasFinder	721199-721229	31	MN693288	Marine virus AFVG_25M432, complete genome	32547-32577	9	0.71
NC_004432_1	1.1|664264|32|NC_004432|CRISPRCasFinder	664264-664295	32	CP033375	Lactobacillus fermentum strain DR9 plasmid unnamed4, complete sequence	24517-24548	10	0.688
NC_004432_1	1.1|664264|32|NC_004432|CRISPRCasFinder	664264-664295	32	NZ_CP023492	Lactobacillus plantarum strain NCIMB 700965 plasmid unamed2, complete sequence	22737-22768	10	0.688
NC_004432_1	1.1|664264|32|NC_004432|CRISPRCasFinder	664264-664295	32	NZ_CP034100	Lactobacillus fermentum strain LMT2-75 plasmid p1, complete sequence	4363-4394	10	0.688
NC_004432_1	1.1|664264|32|NC_004432|CRISPRCasFinder	664264-664295	32	NZ_CP026507	Lactobacillus plantarum strain NCIMB700965.EF.A plasmid punamed2, complete sequence	4411-4442	10	0.688

1. spacer 2.1|721199|31|NC_004432|CRISPRCasFinder matches to NC_031065 (Salmonella phage vB_SnwM_CGG4-1, complete genome) position: , mismatch: 6, identity: 0.806

aacatctgtttttaattcaacaatgtctttc	CRISPR spacer
gcattctgtttttaattcaacaatgtcttct	Protospacer
.   *************************..

2. spacer 2.1|721199|31|NC_004432|CRISPRCasFinder matches to KJ000058 (Salmonella phage STP4-a, complete genome) position: , mismatch: 6, identity: 0.806

aacatctgtttttaattcaacaatgtctttc	CRISPR spacer
gcattctgtttttaattcaacaatgtcttct	Protospacer
.   *************************..

3. spacer 2.1|721199|31|NC_004432|CRISPRCasFinder matches to AP013647 (Uncultured Mediterranean phage uvMED isolate uvMED-CGF-C72-MedDCM-OCT-S41-C96, *** SEQUENCING IN PROGRESS ***) position: , mismatch: 6, identity: 0.806

aacatctgtttttaattcaacaatgtctttc	CRISPR spacer
gttttctatttttaattcaacaatgtcttta	Protospacer
. . ***.********************** 

4. spacer 1.1|664264|32|NC_004432|CRISPRCasFinder matches to AP014611 (Serratia marcescens plasmid p11663 DNA, complete sequence, strain: 11663) position: , mismatch: 7, identity: 0.781

taataaattatataaaaaatgggaaaaagtta	CRISPR spacer
ttttaaattatataaaaaatcggtaaaagaat	Protospacer
*  ***************** ** *****   

5. spacer 1.1|664264|32|NC_004432|CRISPRCasFinder matches to NZ_CP038624 (Arsenophonus nasoniae strain FIN plasmid pArsFIN12, complete sequence) position: , mismatch: 7, identity: 0.781

taataaattatataaaaaatgggaa----aaagtta	CRISPR spacer
tattaaattatataaaaaaagggaactccaga----	Protospacer
** **************** *****    *.*    

6. spacer 1.1|664264|32|NC_004432|CRISPRCasFinder matches to NZ_CP017208 (Borreliella burgdorferi strain B331 plasmid B331_cp32_6, complete sequence) position: , mismatch: 7, identity: 0.781

taataaattatataaaaaatgggaaaaagtta	CRISPR spacer
ttactaattatataaaaaaggggaaaaatgtc	Protospacer
* *. ************** ********  * 

7. spacer 1.1|664264|32|NC_004432|CRISPRCasFinder matches to MF417891 (Uncultured Caudovirales phage clone 10S_13, partial genome) position: , mismatch: 7, identity: 0.781

taataaattatataaaaaatgggaaaaagtta	CRISPR spacer
atatgaattatataaaaaatgggcaaatgaca	Protospacer
  **.****************** *** * .*

8. spacer 2.1|721199|31|NC_004432|CRISPRCasFinder matches to HQ331142 (Salmonella phage S16, complete genome) position: , mismatch: 7, identity: 0.774

aacatctgtttttaattcaacaatgtctttc	CRISPR spacer
gcattctgttcttaattcaacaatgtcttct	Protospacer
.   ******.******************..

9. spacer 1.1|664264|32|NC_004432|CRISPRCasFinder matches to CP003185 (Thermoanaerobacterium saccharolyticum JW/SL-YS485 plasmid pMU3262, complete genome) position: , mismatch: 8, identity: 0.75

taataaattatataaaaaatgggaaaaagtta	CRISPR spacer
tttaaaactatataaaaaatgggagaaagcat	Protospacer
*   ***.****************.****.  

10. spacer 1.1|664264|32|NC_004432|CRISPRCasFinder matches to NC_019956 (Thermoanaerobacterium thermosaccharolyticum M0795 plasmid pTHETHE01, complete sequence) position: , mismatch: 8, identity: 0.75

taataaattatataaaaaatgggaaaaagtta	CRISPR spacer
tttaaaactatataaaaaatgggagaaagcat	Protospacer
*   ***.****************.****.  

11. spacer 1.1|664264|32|NC_004432|CRISPRCasFinder matches to NC_017394 (Borreliella burgdorferi JD1 plasmid JD1 cp32-1+5, complete sequence) position: , mismatch: 8, identity: 0.75

taataaattatataaaaaatgggaaaaagtta	CRISPR spacer
ttactaattatataaaaaagggggaaaatgtc	Protospacer
* *. ************** ***.****  * 

12. spacer 1.1|664264|32|NC_004432|CRISPRCasFinder matches to NC_017394 (Borreliella burgdorferi JD1 plasmid JD1 cp32-1+5, complete sequence) position: , mismatch: 8, identity: 0.75

taataaattatataaaaaatgggaaaaagtta	CRISPR spacer
ttactaattatataaaaaagggggaaaatgtc	Protospacer
* *. ************** ***.****  * 

13. spacer 1.1|664264|32|NC_004432|CRISPRCasFinder matches to NZ_MK275627 (Clostridium perfringens strain JXJA17 plasmid p9, complete sequence) position: , mismatch: 8, identity: 0.75

taataaattatataaaaaatgggaaaaagtta	CRISPR spacer
attcaaataatatagaaaatgggaaaaaagta	Protospacer
   .**** *****.*************. **

14. spacer 1.1|664264|32|NC_004432|CRISPRCasFinder matches to NZ_CP017574 (Bacillus thuringiensis strain SCG04-02 plasmid PSCG364, complete sequence) position: , mismatch: 8, identity: 0.75

taataaattatataaaaaatgggaaaaagtta	CRISPR spacer
tgaaaaactatataaagaatgggaaaattgga	Protospacer
*.* ***.********.**********    *

15. spacer 1.1|664264|32|NC_004432|CRISPRCasFinder matches to NC_014172 (Bacillus thuringiensis BMB171 plasmid pBMB171, complete sequence) position: , mismatch: 8, identity: 0.75

taataaattatataaaaaatgggaaaaagtta	CRISPR spacer
tgaaaaactatataaagaatgggaaaattgga	Protospacer
*.* ***.********.**********    *

16. spacer 1.1|664264|32|NC_004432|CRISPRCasFinder matches to NZ_CP019918 (Borreliella burgdorferi strain PAbe plasmid p_cp32-5-1, complete sequence) position: , mismatch: 8, identity: 0.75

taataaattatataaaaaatgggaaaaagtta	CRISPR spacer
ttactaattatataaaaaagggggaaaatgtc	Protospacer
* *. ************** ***.****  * 

17. spacer 1.1|664264|32|NC_004432|CRISPRCasFinder matches to NZ_CP019918 (Borreliella burgdorferi strain PAbe plasmid p_cp32-5-1, complete sequence) position: , mismatch: 8, identity: 0.75

taataaattatataaaaaatgggaaaaagtta	CRISPR spacer
ttactaattatataaaaaagggggaaaatgtc	Protospacer
* *. ************** ***.****  * 

18. spacer 1.1|664264|32|NC_004432|CRISPRCasFinder matches to NZ_CP019919 (Borreliella burgdorferi strain PAbe plasmid p_cp32-2, complete sequence) position: , mismatch: 8, identity: 0.75

taataaattatataaaaaatgggaaaaagtta	CRISPR spacer
ttactaattatataaaaaagggggaaaatgtc	Protospacer
* *. ************** ***.****  * 

19. spacer 1.1|664264|32|NC_004432|CRISPRCasFinder matches to NZ_CP019920 (Borreliella burgdorferi strain PAbe plasmid p_cp32-3, complete sequence) position: , mismatch: 8, identity: 0.75

taataaattatataaaaaatgggaaaaagtta	CRISPR spacer
ttactaattatataaaaaagggggaaaatgtc	Protospacer
* *. ************** ***.****  * 

20. spacer 1.1|664264|32|NC_004432|CRISPRCasFinder matches to NZ_CP019921 (Borreliella burgdorferi strain PAbe plasmid p_cp32-9-4, complete sequence) position: , mismatch: 8, identity: 0.75

taataaattatataaaaaatgggaaaaagtta	CRISPR spacer
ttactaattatataaaaaagggggaaaatgtc	Protospacer
* *. ************** ***.****  * 

21. spacer 1.1|664264|32|NC_004432|CRISPRCasFinder matches to NZ_CP019921 (Borreliella burgdorferi strain PAbe plasmid p_cp32-9-4, complete sequence) position: , mismatch: 8, identity: 0.75

taataaattatataaaaaatgggaaaaagtta	CRISPR spacer
ttactaattatataaaaaagggggaaaatgtc	Protospacer
* *. ************** ***.****  * 

22. spacer 1.1|664264|32|NC_004432|CRISPRCasFinder matches to NZ_CP019926 (Borreliella burgdorferi strain PAbe plasmid p_lp56, complete sequence) position: , mismatch: 8, identity: 0.75

taataaattatataaaaaatgggaaaaagtta	CRISPR spacer
ttactaattatataaaaaagggggaaaatgtc	Protospacer
* *. ************** ***.****  * 

23. spacer 1.1|664264|32|NC_004432|CRISPRCasFinder matches to NZ_CP009595 (Bacillus cereus strain 3a plasmid pBFC_3, complete sequence) position: , mismatch: 8, identity: 0.75

taataaattatataaaaaatgggaaaaagtta	CRISPR spacer
tgaaaaactatataaagaatgggaaaattgga	Protospacer
*.* ***.********.**********    *

24. spacer 1.1|664264|32|NC_004432|CRISPRCasFinder matches to NZ_CP009606 (Bacillus cereus strain S2-8 plasmid pBFR_2, complete sequence) position: , mismatch: 8, identity: 0.75

taataaattatataaaaaatgggaaaaagtta	CRISPR spacer
tgaaaaactatataaagaatgggaaaattgga	Protospacer
*.* ***.********.**********    *

25. spacer 1.1|664264|32|NC_004432|CRISPRCasFinder matches to NC_018982 (Borrelia burgdorferi 297 plasmid 297_cp32-9, complete sequence) position: , mismatch: 8, identity: 0.75

taataaattatataaaaaatgggaaaaagtta	CRISPR spacer
ttactaattatataaaaaagggggaaaatgtc	Protospacer
* *. ************** ***.****  * 

26. spacer 1.1|664264|32|NC_004432|CRISPRCasFinder matches to NC_017398 (Borreliella burgdorferi N40 plasmid N40_cp32-5, complete sequence) position: , mismatch: 8, identity: 0.75

taataaattatataaaaaatgggaaaaagtta	CRISPR spacer
ttactaattatataaaaaagggggaaaatgtc	Protospacer
* *. ************** ***.****  * 

27. spacer 1.1|664264|32|NC_004432|CRISPRCasFinder matches to NZ_CP016746 (Lactococcus lactis subsp. cremoris strain JM1 plasmid pMPJM1, complete sequence) position: , mismatch: 8, identity: 0.75

-taataaattatataaaaaatgggaaaaagtta	CRISPR spacer
gttgtaag-tatataaaaaaggggaaaaacatg	Protospacer
 * .***. *********** ********  *.

28. spacer 1.1|664264|32|NC_004432|CRISPRCasFinder matches to NC_011722 (Borreliella burgdorferi ZS7 plasmid ZS7_cp32-9, complete sequence) position: , mismatch: 8, identity: 0.75

taataaattatataaaaaatgggaaaaagtta	CRISPR spacer
ttactaattatataaaaaagggggaaaatgtc	Protospacer
* *. ************** ***.****  * 

29. spacer 1.1|664264|32|NC_004432|CRISPRCasFinder matches to NC_000948 (Borreliella burgdorferi B31 plasmid cp32-1, complete sequence) position: , mismatch: 8, identity: 0.75

taataaattatataaaaaatgggaaaaagtta	CRISPR spacer
ttactaattatataaaaaagggggaaaatgtc	Protospacer
* *. ************** ***.****  * 

30. spacer 1.1|664264|32|NC_004432|CRISPRCasFinder matches to NC_000949 (Borreliella burgdorferi B31 plasmid cp32-3, complete sequence) position: , mismatch: 8, identity: 0.75

taataaattatataaaaaatgggaaaaagtta	CRISPR spacer
ttactaattatataaaaaagggggaaaatgtc	Protospacer
* *. ************** ***.****  * 

31. spacer 1.1|664264|32|NC_004432|CRISPRCasFinder matches to NC_000951 (Borreliella burgdorferi B31 plasmid cp32-6, complete sequence) position: , mismatch: 8, identity: 0.75

taataaattatataaaaaatgggaaaaagtta	CRISPR spacer
ttactaattatataaaaaagggggaaaatgtc	Protospacer
* *. ************** ***.****  * 

32. spacer 1.1|664264|32|NC_004432|CRISPRCasFinder matches to NC_000953 (Borreliella burgdorferi B31 plasmid cp32-8, complete sequence) position: , mismatch: 8, identity: 0.75

taataaattatataaaaaatgggaaaaagtta	CRISPR spacer
ttactaattatataaaaaagggggaaaatgtc	Protospacer
* *. ************** ***.****  * 

33. spacer 1.1|664264|32|NC_004432|CRISPRCasFinder matches to NC_000954 (Borreliella burgdorferi B31 plasmid cp32-9, complete sequence) position: , mismatch: 8, identity: 0.75

taataaattatataaaaaatgggaaaaagtta	CRISPR spacer
ttactaattatataaaaaagggggaaaatgtc	Protospacer
* *. ************** ***.****  * 

34. spacer 1.1|664264|32|NC_004432|CRISPRCasFinder matches to NC_000956 (Borreliella burgdorferi B31 plasmid lp56, complete sequence) position: , mismatch: 8, identity: 0.75

taataaattatataaaaaatgggaaaaagtta	CRISPR spacer
ttactaattatataaaaaagggggaaaatgtc	Protospacer
* *. ************** ***.****  * 

35. spacer 1.1|664264|32|NC_004432|CRISPRCasFinder matches to NZ_CP015800 (Borrelia mayonii strain MN14-1539 plasmid cp32-3, complete sequence) position: , mismatch: 8, identity: 0.75

taataaattatataaaaaatgggaaaaagtta	CRISPR spacer
ttactaattatataaaaaagggggaaaatgtc	Protospacer
* *. ************** ***.****  * 

36. spacer 1.1|664264|32|NC_004432|CRISPRCasFinder matches to NZ_CP019846 (Borreliella burgdorferi plasmid cp32-1, complete sequence) position: , mismatch: 8, identity: 0.75

taataaattatataaaaaatgggaaaaagtta	CRISPR spacer
ttactaattatataaaaaagggggaaaatgtc	Protospacer
* *. ************** ***.****  * 

37. spacer 1.1|664264|32|NC_004432|CRISPRCasFinder matches to NZ_CP019847 (Borreliella burgdorferi plasmid cp32-3, complete sequence) position: , mismatch: 8, identity: 0.75

taataaattatataaaaaatgggaaaaagtta	CRISPR spacer
ttactaattatataaaaaagggggaaaatgtc	Protospacer
* *. ************** ***.****  * 

38. spacer 1.1|664264|32|NC_004432|CRISPRCasFinder matches to NZ_CP019848 (Borreliella burgdorferi plasmid cp32-4, complete sequence) position: , mismatch: 8, identity: 0.75

taataaattatataaaaaatgggaaaaagtta	CRISPR spacer
ttactaattatataaaaaagggggaaaatgtc	Protospacer
* *. ************** ***.****  * 

39. spacer 1.1|664264|32|NC_004432|CRISPRCasFinder matches to NZ_CP019849 (Borreliella burgdorferi plasmid cp32-5, complete sequence) position: , mismatch: 8, identity: 0.75

taataaattatataaaaaatgggaaaaagtta	CRISPR spacer
ttactaattatataaaaaagggggaaaatgtc	Protospacer
* *. ************** ***.****  * 

40. spacer 1.1|664264|32|NC_004432|CRISPRCasFinder matches to NZ_CP019850 (Borreliella burgdorferi plasmid cp32-9, complete sequence) position: , mismatch: 8, identity: 0.75

taataaattatataaaaaatgggaaaaagtta	CRISPR spacer
ttactaattatataaaaaagggggaaaatgtc	Protospacer
* *. ************** ***.****  * 

41. spacer 1.1|664264|32|NC_004432|CRISPRCasFinder matches to NZ_CP019855 (Borreliella burgdorferi plasmid lp56, complete sequence) position: , mismatch: 8, identity: 0.75

taataaattatataaaaaatgggaaaaagtta	CRISPR spacer
ttactaattatataaaaaagggggaaaatgtc	Protospacer
* *. ************** ***.****  * 

42. spacer 1.1|664264|32|NC_004432|CRISPRCasFinder matches to NZ_CP019756 (Borreliella burgdorferi strain B31_NRZ isolate B31 plasmid p_cp32-1_1, complete sequence) position: , mismatch: 8, identity: 0.75

taataaattatataaaaaatgggaaaaagtta	CRISPR spacer
ttactaattatataaaaaagggggaaaatgtc	Protospacer
* *. ************** ***.****  * 

43. spacer 1.1|664264|32|NC_004432|CRISPRCasFinder matches to NZ_CP019756 (Borreliella burgdorferi strain B31_NRZ isolate B31 plasmid p_cp32-1_1, complete sequence) position: , mismatch: 8, identity: 0.75

taataaattatataaaaaatgggaaaaagtta	CRISPR spacer
ttactaattatataaaaaagggggaaaatgtc	Protospacer
* *. ************** ***.****  * 

44. spacer 1.1|664264|32|NC_004432|CRISPRCasFinder matches to NZ_CP019757 (Borreliella burgdorferi strain B31_NRZ isolate B31 plasmid p_cp32-2, complete sequence) position: , mismatch: 8, identity: 0.75

taataaattatataaaaaatgggaaaaagtta	CRISPR spacer
ttactaattatataaaaaagggggaaaatgtc	Protospacer
* *. ************** ***.****  * 

45. spacer 1.1|664264|32|NC_004432|CRISPRCasFinder matches to NZ_CP019758 (Borreliella burgdorferi strain B31_NRZ isolate B31 plasmid p_cp32-3, complete sequence) position: , mismatch: 8, identity: 0.75

taataaattatataaaaaatgggaaaaagtta	CRISPR spacer
ttactaattatataaaaaagggggaaaatgtc	Protospacer
* *. ************** ***.****  * 

46. spacer 1.1|664264|32|NC_004432|CRISPRCasFinder matches to NZ_CP019759 (Borreliella burgdorferi strain B31_NRZ isolate B31 plasmid p_cp32-4, complete sequence) position: , mismatch: 8, identity: 0.75

taataaattatataaaaaatgggaaaaagtta	CRISPR spacer
ttactaattatataaaaaagggggaaaatgtc	Protospacer
* *. ************** ***.****  * 

47. spacer 1.1|664264|32|NC_004432|CRISPRCasFinder matches to NZ_CP019760 (Borreliella burgdorferi strain B31_NRZ isolate B31 plasmid p_cp32-9, complete sequence) position: , mismatch: 8, identity: 0.75

taataaattatataaaaaatgggaaaaagtta	CRISPR spacer
ttactaattatataaaaaagggggaaaatgtc	Protospacer
* *. ************** ***.****  * 

48. spacer 1.1|664264|32|NC_004432|CRISPRCasFinder matches to NZ_CP019766 (Borreliella burgdorferi strain B31_NRZ isolate B31 plasmid p_lp56, complete sequence) position: , mismatch: 8, identity: 0.75

taataaattatataaaaaatgggaaaaagtta	CRISPR spacer
ttactaattatataaaaaagggggaaaatgtc	Protospacer
* *. ************** ***.****  * 

49. spacer 1.1|664264|32|NC_004432|CRISPRCasFinder matches to NZ_CP053994 (Bacillus cereus strain FDAARGOS_780 plasmid unnamed1, complete sequence) position: , mismatch: 8, identity: 0.75

taataaattatataaaaaatgggaaaaagtta	CRISPR spacer
tgaaaaactatataaagaatgggaaaattgga	Protospacer
*.* ***.********.**********    *

50. spacer 1.1|664264|32|NC_004432|CRISPRCasFinder matches to NZ_CP043831 (Bacillus sp. BS98 plasmid unnamed1) position: , mismatch: 8, identity: 0.75

taataaattatataaaaaatgggaaaaagtta	CRISPR spacer
tgaaaaactatataaagaatgggaaaattgga	Protospacer
*.* ***.********.**********    *

51. spacer 1.1|664264|32|NC_004432|CRISPRCasFinder matches to NC_004971 (Borrelia burgdorferi 297 plasmid cp18-2, complete sequence) position: , mismatch: 8, identity: 0.75

taataaattatataaaaaatgggaaaaagtta	CRISPR spacer
ttactaattatataaaaaagggggaaaatgtc	Protospacer
* *. ************** ***.****  * 

52. spacer 1.1|664264|32|NC_004432|CRISPRCasFinder matches to NC_011731 (Borreliella burgdorferi ZS7 plasmid ZS7_cp32-1, complete sequence) position: , mismatch: 8, identity: 0.75

taataaattatataaaaaatgggaaaaagtta	CRISPR spacer
ttactaattatataaaaaagggggaaaatgtc	Protospacer
* *. ************** ***.****  * 

53. spacer 1.1|664264|32|NC_004432|CRISPRCasFinder matches to NC_011735 (Borreliella burgdorferi ZS7 plasmid ZS7_cp32-12, complete sequence) position: , mismatch: 8, identity: 0.75

taataaattatataaaaaatgggaaaaagtta	CRISPR spacer
ttactaattatataaaaaagggggaaaatgtc	Protospacer
* *. ************** ***.****  * 

54. spacer 1.1|664264|32|NC_004432|CRISPRCasFinder matches to NZ_CP017203 (Borreliella burgdorferi strain B331 plasmid B331_cp32_1, complete sequence) position: , mismatch: 8, identity: 0.75

taataaattatataaaaaatgggaaaaagtta	CRISPR spacer
ttactaattatataaaaaagggggaaaatgtc	Protospacer
* *. ************** ***.****  * 

55. spacer 1.1|664264|32|NC_004432|CRISPRCasFinder matches to NZ_CP017205 (Borreliella burgdorferi strain B331 plasmid B331_cp32_11, complete sequence) position: , mismatch: 8, identity: 0.75

taataaattatataaaaaatgggaaaaagtta	CRISPR spacer
ttactaattatataaaaaagggggaaaatgtc	Protospacer
* *. ************** ***.****  * 

56. spacer 1.1|664264|32|NC_004432|CRISPRCasFinder matches to NZ_CP017206 (Borreliella burgdorferi strain B331 plasmid B331_cp32_4, complete sequence) position: , mismatch: 8, identity: 0.75

taataaattatataaaaaatgggaaaaagtta	CRISPR spacer
ttactaattatataaaaaagggggaaaatgtc	Protospacer
* *. ************** ***.****  * 

57. spacer 1.1|664264|32|NC_004432|CRISPRCasFinder matches to NZ_CP015784 (Borrelia mayonii strain MN14-1420 plasmid cp32-3, complete sequence) position: , mismatch: 8, identity: 0.75

taataaattatataaaaaatgggaaaaagtta	CRISPR spacer
ttactaattatataaaaaagggggaaaatgtc	Protospacer
* *. ************** ***.****  * 

58. spacer 1.1|664264|32|NC_004432|CRISPRCasFinder matches to NZ_CP009368 (Bacillus cereus strain FM1 plasmid unnamed, complete sequence) position: , mismatch: 8, identity: 0.75

taataaattatataaaaaatgggaaaaagtta	CRISPR spacer
tgaaaaactatataaacaatgggaaaattgga	Protospacer
*.* ***.******** **********    *

59. spacer 1.1|664264|32|NC_004432|CRISPRCasFinder matches to NZ_CP009336 (Bacillus thuringiensis strain HD1011 plasmid 1, complete sequence) position: , mismatch: 8, identity: 0.75

taataaattatataaaaaatgggaaaaagtta	CRISPR spacer
tgaaaaactatataaacaatgggaaaattgga	Protospacer
*.* ***.******** **********    *

60. spacer 1.1|664264|32|NC_004432|CRISPRCasFinder matches to NZ_CP053992 (Bacillus cereus strain FDAARGOS_781 plasmid unnamed2, complete sequence) position: , mismatch: 8, identity: 0.75

taataaattatataaaaaatgggaaaaagtta	CRISPR spacer
tgaaaaactatataaagaatgggaaaattgga	Protospacer
*.* ***.********.**********    *

61. spacer 2.1|721199|31|NC_004432|CRISPRCasFinder matches to JX181825 (Salmonella phage STML-198, complete genome) position: , mismatch: 8, identity: 0.742

aacatctgtttttaattcaacaatgtctttc	CRISPR spacer
gcattctgttcttaattcaataatgtcttct	Protospacer
.   ******.*********.********..

62. spacer 2.1|721199|31|NC_004432|CRISPRCasFinder matches to NC_042044 (Salmonella phage Melville, complete genome) position: , mismatch: 8, identity: 0.742

aacatctgtttttaattcaacaatgtctttc	CRISPR spacer
gcattctgttcttaattcaataatgtcttct	Protospacer
.   ******.*********.********..

63. spacer 2.1|721199|31|NC_004432|CRISPRCasFinder matches to KX961632 (Bacillus phage SBP8a, complete genome) position: , mismatch: 8, identity: 0.742

-----aacatctgtttttaattcaacaatgtctttc	CRISPR spacer
gtataaa-----gtttctaattcaacaatatctttt	Protospacer
     **     ****.************.*****.

64. spacer 2.1|721199|31|NC_004432|CRISPRCasFinder matches to NC_029073 (Geobacillus virus E3, complete genome) position: , mismatch: 8, identity: 0.742

aacatctgtttttaattcaacaatgtctttc	CRISPR spacer
aatatctttttttaattcaacaaattggata	Protospacer
**.**** ***************  *   * 

65. spacer 1.1|664264|32|NC_004432|CRISPRCasFinder matches to NZ_CP024184 (Moraxella osloensis strain KSH plasmid p4, complete sequence) position: , mismatch: 9, identity: 0.719

taataaattatataaaaaatgggaaaaagtta	CRISPR spacer
agataaaaaatataaaaaatgggaaggatgtt	Protospacer
 .*****  ****************..*  * 

66. spacer 1.1|664264|32|NC_004432|CRISPRCasFinder matches to NC_019700 (Oscillatoria acuminata PCC 6304 plasmid pOSCIL6304.01, complete sequence) position: , mismatch: 9, identity: 0.719

taataaattatataaaaaatgggaaaaagtta	CRISPR spacer
gatcctttaatagaaaaaatgtgaaaaagtta	Protospacer
 * .   * *** ******** **********

67. spacer 1.1|664264|32|NC_004432|CRISPRCasFinder matches to NZ_CP024445 (Moraxella osloensis strain NP7 plasmid pNP7-2, complete sequence) position: , mismatch: 9, identity: 0.719

taataaattatataaaaaatgggaaaaagtta	CRISPR spacer
agataaaaaatataaaaaatgggaaggatgtt	Protospacer
 .*****  ****************..*  * 

68. spacer 1.1|664264|32|NC_004432|CRISPRCasFinder matches to NC_015708 (Pseudoalteromonas sp. SANK 73390 plasmid pTML1 carrying thiomarinol biosynthesis cluster) position: , mismatch: 9, identity: 0.719

taataaattatataaaaaatgggaaaaagtta	CRISPR spacer
ctgtatcttgtataaaaaattggaaaaagtct	Protospacer
. .**  **.********** *********. 

69. spacer 1.1|664264|32|NC_004432|CRISPRCasFinder matches to NC_021325 (Clostridium phage vB_CpeS-CP51, complete genome) position: , mismatch: 9, identity: 0.719

taataaattatataaaaaatgggaaaaagtta	CRISPR spacer
ttataaatgatataaaatatgggaatataaat	Protospacer
* ****** ******** ******* * .   

70. spacer 1.1|664264|32|NC_004432|CRISPRCasFinder matches to NC_048074 (Acinetobacter phage vB_AbaM_B09_Aci01-1, complete genome) position: , mismatch: 9, identity: 0.719

taataaattatataaaaaatgggaaaaagtta	CRISPR spacer
tttcccagtatataaaaaacgtgaaaaagttc	Protospacer
*  .  * ***********.* ********* 

71. spacer 2.1|721199|31|NC_004432|CRISPRCasFinder matches to MN693288 (Marine virus AFVG_25M432, complete genome) position: , mismatch: 9, identity: 0.71

aacatctgtttttaattcaacaatgtctttc	CRISPR spacer
cattgaagttttcaattcaacaatatctttt	Protospacer
 *.    *****.***********.*****.

72. spacer 1.1|664264|32|NC_004432|CRISPRCasFinder matches to CP033375 (Lactobacillus fermentum strain DR9 plasmid unnamed4, complete sequence) position: , mismatch: 10, identity: 0.688

taataaattatataaaaaatgggaaaaagtta	CRISPR spacer
taataaattaaataaacaatgggtttccatgt	Protospacer
********** ***** ******     .*  

73. spacer 1.1|664264|32|NC_004432|CRISPRCasFinder matches to NZ_CP023492 (Lactobacillus plantarum strain NCIMB 700965 plasmid unamed2, complete sequence) position: , mismatch: 10, identity: 0.688

taataaattatataaaaaatgggaaaaagtta	CRISPR spacer
taataaattaaataaacaatgggtttccatgt	Protospacer
********** ***** ******     .*  

74. spacer 1.1|664264|32|NC_004432|CRISPRCasFinder matches to NZ_CP034100 (Lactobacillus fermentum strain LMT2-75 plasmid p1, complete sequence) position: , mismatch: 10, identity: 0.688

taataaattatataaaaaatgggaaaaagtta	CRISPR spacer
taataaattaaataaacaatgggtttccatgt	Protospacer
********** ***** ******     .*  

75. spacer 1.1|664264|32|NC_004432|CRISPRCasFinder matches to NZ_CP026507 (Lactobacillus plantarum strain NCIMB700965.EF.A plasmid punamed2, complete sequence) position: , mismatch: 10, identity: 0.688

taataaattatataaaaaatgggaaaaagtta	CRISPR spacer
taataaattaaataaacaatgggtttccatgt	Protospacer
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