CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NC_003923	Staphylococcus aureus subsp. aureus MW2, complete genome	12 crisprs	cas3,DEDDh,DinG,csa3,WYL	7	5	9	0

Results visualization

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CRISPR-Cas detection and classification

Crispr_ID: NC_003923_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_003923_1

166817-166901

Orphan

Consensus_repeat	Method
TTCTACAGGCAATGCAAGTTGGGGTG	CRISPRCasFinder

1 spacers

The CRISPR arrays of NC_003923_1

>merge|NC_003923|1|166817-166901|CRISPRCasFinder
TTCTACAGGCAATGCAAGTTGGGGTGTGGGCCCCAACAAAGAGAAATTGGATTCCCAATTTCTACAGACAATGCAAGTTGGGGTG

>NC_003923|1|1|166817-166901|CRISPRCasFinder
TTCTACAGGCAATGCAAGTTGGGGTG	TGGGCCCCAACAAAGAGAAATTGGATTCCCAAT
TTCTACAGACAATGCAAGTTGGGGTG

Protein	Signature genes	Signature genes Name	Protein_function
NC_003923.1\|WP_000779494.1\|159883_161146_+\|nucleotide-sugar-dehydrogenase	unknown	unknown	gnl\|CDD\|223749
NC_003923.1\|WP_000826671.1\|168951_169926_+\|ABC-transporter-substrate-binding-protein	unknown	unknown	gnl\|CDD\|270271
NC_003923.1\|WP_000605278.1\|175585_182761_+\|amino-acid-adenylation-domain-containing-protein	unknown	unknown	gnl\|CDD\|237108
NC_003923.1\|WP_000356963.1\|166962_167166_-\|hypothetical-protein	unknown	unknown	unknown
NC_003923.1\|WP_000826862.1\|173888_175139_+\|MFS-transporter	unknown	unknown	gnl\|CDD\|340887
NC_003923.1\|WP_000197961.1\|169922_170684_+\|ABC-transporter-permease	unknown	unknown	gnl\|CDD\|223673
NC_003923.1\|WP_000290397.1\|163575_165063_+\|aldehyde-dehydrogenase-family-protein	unknown	unknown	gnl\|CDD\|143435
NC_003923.1\|WP_000590847.1\|168197_168938_+\|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|224041
NC_003923.1\|WP_001237002.1\|162765_163149_-\|YbaN-family-protein	unknown	unknown	gnl\|CDD\|377291
NC_003923.1\|WP_000706137.1\|172477_173503_+\|NAD-dependent-formate-dehydrogenase	unknown	unknown	gnl\|CDD\|181041
NC_003923.1\|WP_001291010.1\|157169_158375_+\|glycosyltransferase-family-4-protein	unknown	unknown	gnl\|CDD\|340825
NC_003923.1\|WP_001092004.1\|171944_172304_+\|DUF2294-domain-containing-protein	unknown	unknown	gnl\|CDD\|227896
NC_003923.1\|WP_001013481.1\|165708_166668_+\|cation-transporter	unknown	unknown	gnl\|CDD\|224151
NC_003923.1\|WP_000171919.1\|167343_167856_+\|DUF4242-domain-containing-protein	unknown	unknown	gnl\|CDD\|379428
NC_003923.1\|WP_000723452.1\|161222_162368_+\|UDP-N-acetylglucosamine-2-epimerase-(non-hydrolyzing)	unknown	unknown	gnl\|CDD\|223458
NC_003923.1\|WP_001238807.1\|155897_157136_+\|oligosaccharide-flippase-family-protein	unknown	unknown	gnl\|CDD\|240532
NC_003923.1\|WP_000171644.1\|170696_171728_+\|acyl-CoA/acyl-ACP-dehydrogenase	unknown	unknown	gnl\|CDD\|224871
NC_003923.1\|WP_000480603.1\|162432_162759_-\|staphylobilin-forming-heme-oxygenase-IsdI	unknown	unknown	gnl\|CDD\|183968
NC_003923.1\|WP_000825101.1\|158385_158943_+\|sugar-transferase	unknown	unknown	gnl\|CDD\|225059
NC_003923.1\|WP_001230668.1\|158942_159830_+\|capsular-polysaccharide-type-5/8-biosynthesis-epimerase-CapN	unknown	unknown	gnl\|CDD\|187543

Protein	Function_ID	Function_description	E-value
NC_003923.1\|WP_000779494.1\|159883_161146_+\|nucleotide-sugar-dehydrogenase	gnl\|CDD\|223749	COG0677, WecC, UDP-N-acetyl-D-mannosaminuronate dehydrogenase [Cell envelope biogenesis, outer membrane].	0
NC_003923.1\|WP_000826671.1\|168951_169926_+\|ABC-transporter-substrate-binding-protein	gnl\|CDD\|270271	cd13553, PBP2_NrtA_CpmA_like, Substrate binding domain of ABC-type nitrate/bicarbonate transporters, a member of the type 2 periplasmic binding fold superfamily. This subfamily includes nitrate (NrtA) and bicarbonate (CmpA) receptors. These domains are found in eubacterial perisplamic-binding proteins that serve as initial receptors in the ABC transport of bicarbonate, nitrate, taurine, or a wide range of aliphatic sulfonates, while other closest homologs are involved in thiamine (vitamin B1) biosynthetic pathway and desulfurization (DszB). After binding their ligand with high affinity, they interact with a cognate membrane transport complex comprised of two integral membrane domains and two cytoplasmically located ATPase domains. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis. These binding proteins belong to the PBP2 superfamily of periplasmic binding proteins that differ in size and ligand specificity, but have similar tertiary structures consisting of two globular subdomains connected by a flexible hinge. They have been shown to bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap.	3.99971e-50
NC_003923.1\|WP_000605278.1\|175585_182761_+\|amino-acid-adenylation-domain-containing-protein	gnl\|CDD\|237108	PRK12467, PRK12467, peptide synthase; Provisional.	0
NC_003923.1\|WP_000826862.1\|173888_175139_+\|MFS-transporter	gnl\|CDD\|340887	cd17329, MFS_MdtH_MDR_like, Multidrug resistance protein MdtH and similar multidrug resistance (MDR) transporters of the Major Facilitator Superfamily. This family is composed of Escherichia coli MdtH and similar multidrug resistance (MDR) transporters from bacteria and archaea, many of which remain uncharacterized. MDR transporters are drug/H+ antiporters (DHA) that mediate the efflux of a variety of drugs and toxic compounds, and confer resistance to these compounds. MdtH confers resistance to norfloxacin and enoxacin. MdtH-like MDR transporters belong to the Major Facilitator Superfamily (MFS) of membrane transport proteins, which are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	1.61322e-72
NC_003923.1\|WP_000197961.1\|169922_170684_+\|ABC-transporter-permease	gnl\|CDD\|223673	COG0600, TauC, ABC-type nitrate/sulfonate/bicarbonate transport system, permease component [Inorganic ion transport and metabolism].	1.22607e-73
NC_003923.1\|WP_000290397.1\|163575_165063_+\|aldehyde-dehydrogenase-family-protein	gnl\|CDD\|143435	cd07117, ALDH_StaphAldA1, Uncharacterized Staphylococcus aureus AldA1 (SACOL0154) aldehyde dehydrogenase-like. Uncharacterized aldehyde dehydrogenase from Staphylococcus aureus (AldA1, locus SACOL0154) and other similar sequences are present in this CD.	0
NC_003923.1\|WP_000590847.1\|168197_168938_+\|ABC-transporter-ATP-binding-protein	gnl\|CDD\|224041	COG1116, TauB, ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component [Inorganic ion transport and metabolism].	1.69369e-112
NC_003923.1\|WP_001237002.1\|162765_163149_-\|YbaN-family-protein	gnl\|CDD\|377291	pfam04304, DUF454, Protein of unknown function (DUF454). Predicted membrane protein.	3.10235e-41
NC_003923.1\|WP_000706137.1\|172477_173503_+\|NAD-dependent-formate-dehydrogenase	gnl\|CDD\|181041	PRK07574, PRK07574, NAD-dependent formate dehydrogenase.	0
NC_003923.1\|WP_001291010.1\|157169_158375_+\|glycosyltransferase-family-4-protein	gnl\|CDD\|340825	cd03794, GT4_WbuB-like, Escherichia coli WbuB and similar proteins. This family is most closely related to the GT1 family of glycosyltransferases. WbuB in E. coli is involved in the biosynthesis of the O26 O-antigen. It has been proposed to function as an N-acetyl-L-fucosamine (L-FucNAc) transferase.	2.36047e-71
NC_003923.1\|WP_001092004.1\|171944_172304_+\|DUF2294-domain-containing-protein	gnl\|CDD\|227896	COG5609, COG5609, Uncharacterized conserved protein [Function unknown].	6.06834e-49
NC_003923.1\|WP_001013481.1\|165708_166668_+\|cation-transporter	gnl\|CDD\|224151	COG1230, CzcD, Co/Zn/Cd efflux system component [Inorganic ion transport and metabolism].	3.08716e-108
NC_003923.1\|WP_000171919.1\|167343_167856_+\|DUF4242-domain-containing-protein	gnl\|CDD\|379428	pfam14026, DUF4242, Protein of unknown function (DUF4242). This family of proteins is functionally uncharacterized. This family of proteins is found in bacteria and archaea. Proteins in this family are typically between 90 and 170 amino acids in length. There is a single completely conserved residue C that may be functionally important.	2.56603e-26
NC_003923.1\|WP_000723452.1\|161222_162368_+\|UDP-N-acetylglucosamine-2-epimerase-(non-hydrolyzing)	gnl\|CDD\|223458	COG0381, WecB, UDP-N-acetylglucosamine 2-epimerase [Cell envelope biogenesis, outer membrane].	0
NC_003923.1\|WP_001238807.1\|155897_157136_+\|oligosaccharide-flippase-family-protein	gnl\|CDD\|240532	cd13127, MATE_tuaB_like, Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins. This family might function as a translocase for lipopolysaccharides and participate in the biosynthesis of cell wall components such as teichuronic acid. The integral membrane proteins from the MATE family are involved in exporting metabolites across the cell membrane and are responsible for multidrug resistance (MDR) in many bacteria and animals. A number of family members are involved in the synthesis of peptidoglycan components in bacteria.	1.56476e-21
NC_003923.1\|WP_000171644.1\|170696_171728_+\|acyl-CoA/acyl-ACP-dehydrogenase	gnl\|CDD\|224871	COG1960, CaiA, Acyl-CoA dehydrogenases [Lipid metabolism].	2.35031e-20
NC_003923.1\|WP_000480603.1\|162432_162759_-\|staphylobilin-forming-heme-oxygenase-IsdI	gnl\|CDD\|183968	PRK13313, PRK13313, staphylobilin-forming heme oxygenase IsdI.	1.40112e-64
NC_003923.1\|WP_000825101.1\|158385_158943_+\|sugar-transferase	gnl\|CDD\|225059	COG2148, WcaJ, Sugar transferases involved in lipopolysaccharide synthesis [Cell envelope biogenesis, outer membrane].	3.22743e-86
NC_003923.1\|WP_001230668.1\|158942_159830_+\|capsular-polysaccharide-type-5/8-biosynthesis-epimerase-CapN	gnl\|CDD\|187543	cd05232, UDP_G4E_4_SDR_e, UDP-glucose 4 epimerase, subgroup 4, extended (e) SDRs. UDP-glucose 4 epimerase (aka UDP-galactose-4-epimerase), is a homodimeric extended SDR. It catalyzes the NAD-dependent conversion of UDP-galactose to UDP-glucose, the final step in Leloir galactose synthesis. This subgroup is comprised of bacterial proteins, and includes the Staphylococcus aureus capsular polysaccharide Cap5N, which may have a role in the synthesis of UDP-N-acetyl-d-fucosamine. This subgroup has the characteristic active site tetrad and NAD-binding motif of the extended SDRs. Extended SDRs are distinct from classical SDRs. In addition to the Rossmann fold (alpha/beta folding pattern with a central beta-sheet) core region typical of all SDRs, extended SDRs have a less conserved C-terminal extension of approximately 100 amino acids. Extended SDRs are a diverse collection of proteins, and include isomerases, epimerases, oxidoreductases, and lyases; they typically have a TGXXGXXG cofactor binding motif. SDRs are a functionally diverse family of oxidoreductases that have a single domain with a structurally conserved Rossmann fold, an NAD(P)(H)-binding region, and a structurally diverse C-terminal region. Sequence identity between different SDR enzymes is typically in the 15-30% range; they catalyze a wide range of activities including the metabolism of steroids, cofactors, carbohydrates, lipids, aromatic compounds, and amino acids, and act in redox sensing. Classical SDRs have an TGXXX[AG]XG cofactor binding motif and a YXXXK active site motif, with the Tyr residue of the active site motif serving as a critical catalytic residue (Tyr-151, human 15-hydroxyprostaglandin dehydrogenase numbering). In addition to the Tyr and Lys, there is often an upstream Ser and/or an Asn, contributing to the active site; while substrate binding is in the C-terminal region, which determines specificity. The standard reaction mechanism is a 4-pro-S hydride transfer and proton relay involving the conserved Tyr and Lys, a water molecule stabilized by Asn, and nicotinamide. Atypical SDRs generally lack the catalytic residues characteristic of the SDRs, and their glycine-rich NAD(P)-binding motif is often different from the forms normally seen in classical or extended SDRs. Complex (multidomain) SDRs such as ketoreductase domains of fatty acid synthase have a GGXGXXG NAD(P)-binding motif and an altered active site motif (YXXXN). Fungal type ketoacyl reductases have a TGXXXGX(1-2)G NAD(P)-binding motif.	7.33242e-118

>NC_003923.1|WP_001013481.1|165708_166668_+|cation-transporter
MNGKKANTINRYKYFHHVNHQKIQQSSKKTLWASLIITLLFTVIEFVGGLVSNSLALLSDSFHMLSDVLALGLSMLAIYFASKKPTARYTFGYLRFEILAAFLNGLALIVISIWILYEAIVRIIYPQPIESGIMFMIASIGLLVNIILTIILVRSLKQEDNINIQSALWHFMGDLLNSIGVIVAVVLIYFTGWRIIDPIISIVISLIILRGGYKITRNAWLILMESVPQHLDTDQIMADIKNIDGILDVHEFHLWSITTEHYSLSAHVVLDKKYEGDDYQAIDQVSSLLKEKYGIAHSTLQIENLQLNPLDEPYFDKLT
>NC_003923.1|WP_000290397.1|163575_165063_+|aldehyde-dehydrogenase-family-protein
MAVNVRDYIAENYGLFINGEFVKGSSDETIEVTNPATGETLSHITRAKDKDVDHAVKVAQEAFESWSLTSKSERAQMLRDIGDKLMAQKDKIAMIETLNNGKPIRETTAIDIPFAARHFHYFASVIETEEGTVNDIDKDTMSIVRHEPIGVVGAVVAWNFPMLLAAWKIAPAIAAGNTIVIQPSSSTPLSLLEVAKIFQEVLPKGVVNILTGKGSESGNAIFNHDGVDKLSFTGSTDVGYQVAEAAAKHLVPATLELGGKSANIILDDANLDLAVEGIQLGILFNQGEVCSAGSRLLVHEKIYDQLVPRLQEAFSNIKVGDPQDEATQMGSQTGKDQLDKIQSYIDAAKESDAQILAGGHRLTENGLDKGFFFEPTLIAVPDNHHKLAQEEIFGPVLTVIKVKDDQEAIDIANDSEYGLAGGVFSQNITRALNIAKAVRTGRIWINTYNQVPEGAPFGGYKKSGIGRETYKGALSNYQQVKNIYIDTSNALKGLY
>NC_003923.1|WP_001237002.1|162765_163149_-|YbaN-family-protein
MRLILIVIGLIFTALGIAGAVLPLLPTTPFLLVAVFCFARSSDRFYNWLINQKIYKEYVENFYLHRGYTLQQKIKILISLYIVIGFSIYMVDVLAVRIGLIIMVIIQTAVLFTFVKTLPKSNHKIEE
>NC_003923.1|WP_000480603.1|162432_162759_-|staphylobilin-forming-heme-oxygenase-IsdI
MFMAENRLQLQKGSAEETIERFYNRQGIETIEGFQQMFVTKTLNTEDTDEVKILTIWESEDSFNNWLNSDVFKEAHKNVRLKSDDDGQQSPILSNKVFKYDIGYHYQK
>NC_003923.1|WP_000723452.1|161222_162368_+|UDP-N-acetylglucosamine-2-epimerase-(non-hydrolyzing)
MKKIMVIFGTRPEAIKMAPLVKEIDHNGNFEANIVITAQHRDMLDSVLSIFDIQADHDLNIMQDQQTLAGLTANALAKLDSIINEEQPDMILVHGDTTTTFVGSLAAFYHQIPVGHVEAGLRTHQKYSPFPEELNRVMVSNIAELNFAPTVIAAKNLLFENKDKERIFITGNTVIDALSTTVQNDFVSTIINKHKGKKVILLTAHRRENIGEPMHQIFKAVRDLADEYKDVVFIYPMHRNPKVRAIAEKYLSGRNRIELIEPLDAIEFHNFTNQSYLVLTDSGGIQEEAPTFGKPVLVLRNHTERPEGVEAGTSRVIGTDYDNIVRNVKQLIEDDEAYQRMSQANNPYGDGQASRRICEAIEYYFGLRTDKPDEFVPLRHK
>NC_003923.1|WP_000779494.1|159883_161146_+|nucleotide-sugar-dehydrogenase
MKLTVVGLGYIGLPTSIMFAKHGVDVLGVDINQQTIDKLQSGQISIEEPGLQEIYEEVLSSGKLKVSTTPEASDVFIIAVPTPNNDDQYRSCDISLVMRALDSILPFLKKGNTIIVESTIAPKTMDDFVKPVIENLGFTIGEDIYLVHCPERVLPGKILEELVHNNRIIGGVTKACIEAGKRVYRTFVQGEMIETDARTAEMSKLMENTYRDVNIALANELTKICNNLNINVLDVIEMANKHPRVNIHQPGPGVGGHCLAVDPYFIIAKDPENAKLIQTGREINNSMPAYVVDTTKQIIKALSGNKVTVFGLTYKGDVDDIRESPAFDIYELLNQEPDIEVCAYDPHVELDFVEHDMSHAVKDASLVLILSDHSEFKNLSDSHFDKMKHKVIFDTKNVVKSSFEDVSYYNYGNIFNFIDK
>NC_003923.1|WP_001230668.1|158942_159830_+|capsular-polysaccharide-type-5/8-biosynthesis-epimerase-CapN
MRKNILITGVHGYIGNALKDKLIEQGHQVDQINVRNQLWKSTSFKDYDALIHTAALVHNNSPQARLSDYMQVNMLLTKQLAQKAKSEDVKQFIFMSTMAVYGKEGQVGKSDQIDTQTPMNPTTNYGISKKFAEQALQELISDSFKVAIVRPPMIYGAHCPGNFQRLMQLSKRLPIIPNINNQRSALYIKHLTAFIDQLISLEVTGVYHPQDSFYFDTSSVMYEIRRQSHRKTVLINMPSVLNKYFNKLSVFRKLFGNLIYSNTLYENNNALEVIPGKMSLVIADIMDETTTKDKA
>NC_003923.1|WP_000825101.1|158385_158943_+|sugar-transferase
MKRLFDVVSSIYGLVVLSPILLITALLIKMESPGPAIFKQKRPTINNELFNIYKFRSMKIDTPNVATDLMDSTSYITKTGKVIRKTSIDELPQLLNVLKGEMSIVGPRPALYNQYELIEKRTKVNVHTIRPGVTGLAQVMGRDDITDDQKVAYDHYYLTHQSMMLDMYIIYKTIKNIVTSEGVHH
>NC_003923.1|WP_001291010.1|157169_158375_+|glycosyltransferase-family-4-protein
MSEKKILILCQYFYPEYVSSATLPTQLAEDLIANHINVDVMCGWPYEYSNHKQVSKTEMHRGICIRRLKYSRFNNKSKVGRIINFFSLFSKFVINIPKMLKYDQILVYSNPPILPLIPDVLHRLLKKKYSFVVYDIAPDNAIKTGATRPGSMIDKLMRYINRHVYKNAENVIVLGTEMKNYLLNHQISKNADNIHVIPNWYDMRQLQDNRIYNDTFKAYREQYDKILLYSGNMGQLQDMETLISFLKLNKDQPQTLTILCGHGKKFADVKTAIEDHRIENVKMFEFLTGTDYADVLKIADVCIASLIKEGVGLGVPSKNYGYLAAKKALVLIMDKQSDIVQHVEQYDAGIQIDNGDAHAIYNFINTHSSKELHEMGERAHQLFKDKYTREINTMKYYNLLK
>NC_003923.1|WP_001238807.1|155897_157136_+|oligosaccharide-flippase-family-protein
MRLNKFIGDSFLMILSSGIAQVILIITTPIITRLYSPTEFGEFTIFSNIAMILIPIINARYDLLIVNTKNDRSANILSQISFLISLLILLILIPIFAISACLYPNFILDFIFIIIMLFLVSLTNIFTNYLNKERKYKVLSLINVFRAGSMALLQIIFGLLALGSLGLIIGFSLSYIAGITLGYKTFKKHFNIVRDKEETKALFLENKNQLVYSTPSILLNSLSFSVVVFFIGILYTNTEVGIYGMAIRVLGIPVTIISLGLSKIFMQQANDYYIEHGNFRNLLLKFSSILVIVSIILYVPLYLFSEELVNILLGHSWVDAITVIKIVIPLFVIRLIVSTVSLSVIVLQKQQLELILQALFLIGTTATFVISKMLNLTFLNFVSINTIVLIVSYMIFFIALYYFAKNKQFKNS
>NC_003923.1|WP_000356963.1|166962_167166_-|hypothetical-protein
MDKESVVASLARNKKIAVETMAGQRYIIERILHTNDEKHIHILKPKDVVLDVDSIKEIDENHLNDAT
>NC_003923.1|WP_000171919.1|167343_167856_+|DUF4242-domain-containing-protein
MTLFLLEANNLDFASTKEELEAKAASLSTKTIPTLIEVQATENLTHGYFIVEANDEAEAKQFLTEADISIQLVKEVRLVGKDLDEVKNGDAHVDYLVTWNIPEGITMDQYLARKKKNSVHYEEVPEVEFKRTYVCEDMSKCICLYNAPDEEAVRRARKAVDTPIDGIEKL
>NC_003923.1|WP_000590847.1|168197_168938_+|ABC-transporter-ATP-binding-protein
MIKIQQLQHHFGSHKVIHNFNLDISKGEIVTFIGKSGCGKSTLLNIIGGFIHPSSGRVIIDNEIKQQPSPDCLMLFQHHNLLPWKTINDNIRIGFRQKISDEEINAQLKLVDLEGRGKHFPEQLSGGMKQRVALCRAHVHKPNVILMDEPLGALDAFTRYKLQDQLVQLKHKTQSTIILVTHDIDEAIYLSDRIVLLGEGCNIISQYEITASHPRSRNDSHLLKVRNEIMETFALNHHQVEPEYYL
>NC_003923.1|WP_000826671.1|168951_169926_+|ABC-transporter-substrate-binding-protein
MKRLSIIVIIGIFIITGCDWQRTSKEPSKNAQNQQVIKIGYLPITHSANLMMTKKLLSQYNHPKYKLELVKFNNWPDLMDALNSGRIDGASTLIELAMKSKQKGSNIKAVALGHHEGNVIMGQKGMHLNEFNNNGDDYHFGIPHRYSTHYLLLEELRKQLKIKPGHFSYHEMSPAEMPAALSEHRITGYSVAEPFGALGEKLGKGKTLKHGDDVIPDAYCCVLVLRGELLDQHKDVAQAFVQDYKKSGFKMNDRKQSVDIMTHHFKQSRDVLTQSAAWTSYGDLTIKPSGYQEITTLVKQHHLFNPPAYDDFVEPSLYKEASRS
>NC_003923.1|WP_000197961.1|169922_170684_+|ABC-transporter-permease
MTRPTNNKFILPIITFIIFLGIWEMVIIIGHYQPVLLPGPALVGKSIWTFIVTGEIFQHLAISLWRFVAGFVVALLVAIPLGFLLGRNRWLYNAIEPLFQLIRPISPIAWAPFVVLWFGIGSLPAIAIIFIAAFFPIVFNTIKGVRDIEPQYLKIAANLNLTGWSLYRNILFPGAFKQIMAGIHMAVGTSWIFLVSGEMIGAQSGLGFLIVDARNMLNLEDVLAAIFFIGLFGFIIDRFISYIEQFILRRFGE
>NC_003923.1|WP_000171644.1|170696_171728_+|acyl-CoA/acyl-ACP-dehydrogenase
MTLETLIKEQLDPHLVEVDEGTYYPRTFIQQLFVDGYFGEAALRKNAEVIEAVSQSCLTTGFCLWCQLAFSTYLENATQPHLNNDLQQQLLSGEILGATGLSNPMKSFNDLEKLNLEHTYVDGQLVVSGRMPAVSNIQEDHYFGAISKHESSDEFVMFILRANQDGITLVEKTNFLGVNGSATYQITLNQVVVPQSQIITHDAKQFAATIRPQFIAYQIPIGLGSIKSSLELIDAFSNAQNGINQYLEYDVEAFKKRYRQLREEYYAILDDGNLTSHLNELISLKKDIGYLLLDVNQASVVNGGSRAYTPYSPQVRKLKEGFFFAALTPTLRHLGKLEAELKG
>NC_003923.1|WP_001092004.1|171944_172304_+|DUF2294-domain-containing-protein
MNTIDTHTKEQQFSNLVRSYRKEYVGKGPNSIRVSFKDNWAIAHMTGVLSKVESFYLNDKRNESMLHYTRTEKIKQMYKEIDVNEMESLVGAKFVKLFTDIDLNDDEVISIFVFDKSIE
>NC_003923.1|WP_000706137.1|172477_173503_+|NAD-dependent-formate-dehydrogenase
MKIVALFPEAVEGQENQLLNTKKALGLKTFLEERGHEFIILADNGEDLDKHLPDMDVIISAPFYPAYMTRERIEKAPNLKLAITAGVGSDHVDLAAASEHNIGVVEVTGSNTVSVAEHAVMDLLILLRNYEEGHRQSVEGEWNLSQVGNHAHELQHKTIGIFGFGRIGQLVAERLAPFNVTLQHYDPINQQDHKLSKFVSFDELVSTSDAITIHAPLTPETDNLFDKDVLSRMKKHSYLVNTARGKIVNRDALVEALASEHLQGYAGDVWYPQPAPADHPWRTMPRNAMTVHYSGMTLEAQKRIEDGVKDILERFFNHEPFQDKDIIVASGRIASKSYTAK
>NC_003923.1|WP_000826862.1|173888_175139_+|MFS-transporter
MKRLSTTLKVRLISNFLQLIITTAFIPFIALYLTDMLSQSIVGIYLVGLVVLKFPLSIISGYLIEIFPKKLLVLIYQATMVIMLVFMGVFGSHQLWQIIGFCVAYAIFTIVWGLQFPVMDTLIMDAITEDVEHYIYKISYWMTNLSVAIGALLGGLMYGYSMLLLFLIAACIFLIVLFILYIWLPQDRNQVKQSDDKRHASRYQKLQIMNIFRSYKLVLKDRNYMLLISGFSIIMMGEFSISSYIAIRLKDQFETISIGSYDITGAKMLAILLMINTVVVILLTYSISKVVLKIDFKKALITGLLIYIVGYSGLTYLNQFGLLVVFMIIATVGEIIYSPIVSEQRFKIIPKAKRGTYSAVNALGIHFSETLARLGIVLGVFLTSLQMGLYMFIVLTIGASMLVAGVFGGQKQVNTN
>NC_003923.1|WP_000605278.1|175585_182761_+|amino-acid-adenylation-domain-containing-protein
MIMGNLRFQQEYFRIYKNNTESTTHRNAYWVKLAKNVEATKMMYALSTIVQQHASIRHFFDVTTDDNLTMILHEFLPFIEIKQVPSSSANYDLEAFFKQELSTYHFNDSPLFKVKLFQFADAAYILLDFHVSIFDDSQIDIFLDDLCNAYRGNTVINNTRQHAHINRNDDKDNQDASHIALDSNYFRLENNSDIHIDSYFPIKHPFEQALYQTYLIDDMTSIDMASLAVSVYLANHIMSQQHDVTLGIHVPSHLPNDLHGNIVPLTLTIDAKDVCQRFTTDFNKCVLQNMSQLQCAKSSLSLETIFHCYHHMMSCCNDVIEDVHQIHDAHTSLADIEIFPHQHGFKIIYNSAAYDLLSIETLSDLVRNIYLQITEENGNKRTTVDELNLMTERDIQLYDDINLSLPEIDDAQTVVTLFEQQVEATPNHVAVQFDGVFITYQTLNARANDLAHRLRNQYGVEPNDRVAVIAEKSIEMIIAMIGVLKAGGAYVPIDLNYPSDRQEYILKDVTPKVVITYQALYENGKQNINHIDLNKIAWKNIDNLSKCNTLEDHAYVIYTSGTTGNPKGTLIPHRGIVRLVHQNHYVPLNEETTILLSGTIAFDAATFEIYGALLNGGKLIVAKKEQLLNPIAVEQLINENDVNTMWLTSSLFNQIASERIEVLVPLKYLLIGGEVLNAKWVDLLNQKPKHPQIINGYGPTENTTFTTTYNIPNKVPNRIPIGKPILGTHVYIMQGERRCGVGIPGELCTSGFGLAAGYLNQPELTADKFIKDSNINQLMYRSGDIVRLLPDGNIDYLYRKDKQVKIRGFRIELSEVEHALERIQGINKAVVIVQNHDQDQYIVAYYEAMHTLSHNKIKSQLRMTLPEYMIPVNFMHIEQIPITINGKLDKKALPIMDYVDTDAYVAPSTDTEHLLCQIFADILHVNQVGIHDNFFELGGHSLKATLVVNRIEASTGKRLQIGDLLQKPTVFELAQAIAKVQEQNYEVIPETIVKDDYVLSSAQKRMYLLWKSNHKDTVYNVPFLWRLSSELNVAQLRQAVQRLIARHEILRTQYIVVDDEVRQRIVADVAVDFEEVNTHFTDEQEIMRQFVAPFNLEKPSQIRVRYIRSPLHAYLFIDTHHIINDGMSNIQLMNDLNALYQHKLLLPLKLQYKDYSEWMSHRDMTKHRQYWLSQFKDEVPILSLPTDYVRPNIKTTNGAMMSFTMNQQMRQLLQKYVEKHQITDFMFFMSVVMTLLSRYARKDDVVVGSVMSARMHKGTEQMLGMFANTLVYRGQPSPDKMWTQFLQEVKEMSLEAYEHQEYPFECLVNDLDQSHDASRNPLFDVMLVLQNNETNHAHFGHSKLTHIQPKSVTAKFDLSFIIEEDRDDYTINIEYNTDLYHSETVRHMGNQCMIMIDYILKHQDTLQICDIPNGTEELLNWVNTHVNDRMLNVPGNKSIISYFNEVVSRQGNHVALVMNDLTMTYETLRNYVDAIAHMLLSNGVGNGQRVALFTERSFEMIAAMLATVKVGASYIPIDIDFPNKRQGAILEDAKVTAVMSYGVEIETTLPVIQLENAKGFVESKENEQYDDLHGNQLENTAMLDNEMYAIYTSGTTGMPKGVAIRQRNLLNLVHAWSTELQLGDNEVFLQHANIVFDASVMEIYCCLLNGHTLVIPDREERVNPEQLQQLINKHRVTVASIPLQMCSVMEDFYIEKLITGGATSTASFVKYIEKHCGTYFNAYGPSESTVITSYWSHQCGDLIPETIPIGKPLSNIQVYIMSDGLLCGIGMPGELCIAGDSLAIGYINRPELMADKWQNNPFGKGKLYHSGDLARYTSDGQIEFLGRIDKQVKVNGYRIELDEIENAILAIRGISDCVVTVSHFDTHDILNAYYVGEQQMEQDLKQYLNDHLPKYMIPKTITHIDYMPLTTNDKVDTTRLPNPSTIQQSNKVYSEPSNEIEQTFVDVFGEVLKQNDVGVDDDFFELGGNSLEAMLVVSHLKRFGHHISMQTLYQYKTVRQIVNYMHQNQQSLVALPDNLSELQKIVMSRYNLGVLEDSLSHRPIGNTLLTGATGFLGAYLIEALQGYSHRIYCFIRADNEEIARYKLMTNLNDYFSEETVEMMLSNIEVIVGDFECMDDVVLPENMDTIIHAGARTDHFGDDDEFEKVNVQGTVDVIRLAQQHHARLIYVSTISVGTYFDIDTEDVTFSEADVYKGQLLTSPYTRSKFYSELKVLEAVNNGLDGRIVRVGNLTSPYNGRWHMRNIKTNRFSMVMNDLLQLDCIGVSMAEMPVDFSFVDTTARQIVALAQVNTPQIIYHVLSPNKMPVKSLLECVKRKEIELVSDESFNEILQKQDMYETIGLTSVDREQQLAMIDTTLTLKIMNHISEKWPTITNNWLYHWAQYIKTIFNK

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Crispr_ID: NC_003923_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_003923_2

290101-290291

Orphan

Consensus_repeat	Method
GTGCAAGTTGGCGGGGCCCCAACA	CRT

3 spacers

The CRISPR arrays of NC_003923_2

>merge|NC_003923|2|290101-290291|CRT
GTGTTATATTGGCGGGCCCCAACATAGAAGCTGGCGGAAAGTCAGCATACAATAATGTGCAAGTTGGCGGGGCCCCAACACAGAGAATTTCGAAAAGAAATTCTACAGGCAATGCAAGTTGGCGGGGCCCCAACATAGAAGCTGGCGGAAAGTCAGCTTACAATAATGTGCAAGTTGGCGGGGCCCCAACA

>NC_003923|2|1|290101-290291|CRT
GTGTTATATTGGCGGGCCCCAACA	TAGAAGCTGGCGGAAAGTCAGCATACAATAAT
GTGCAAGTTGGCGGGGCCCCAACA	CAGAGAATTTCGAAAAGAAATTCTACAGGCA
ATGCAAGTTGGCGGGGCCCCAACA	TAGAAGCTGGCGGAAAGTCAGCTTACAATAAT
GTGCAAGTTGGCGGGGCCCCAACA

Protein	Signature genes	Signature genes Name	Protein_function
NC_003923.1\|WP_000240920.1\|278581_280270_+\|CDP-glycerol-glycerophosphotransferase-family-protein	unknown	unknown	gnl\|CDD\|367953
NC_003923.1\|WP_001789860.1\|291364_291499_+\|hypothetical-protein	unknown	unknown	unknown
NC_003923.1\|WP_000975365.1\|280302_282024_+\|poly(ribitol-phosphate)-beta-N-acetylglucosaminyltransferase	unknown	unknown	gnl\|CDD\|376098
NC_003923.1\|WP_000757884.1\|294070_295069_-\|LacI-family-DNA-binding-transcriptional-regulator	unknown	unknown	gnl\|CDD\|224525
NC_003923.1\|WP_001066553.1\|295969_297346_-\|MFS-transporter	unknown	unknown	gnl\|CDD\|129794
NC_003923.1\|WP_000337383.1\|297579_298572_+\|linear-amide-C-N-hydrolase	unknown	unknown	gnl\|CDD\|225591
NC_003923.1\|WP_000164010.1\|288600_290037_+\|6-phospho-beta-glucosidase	unknown	unknown	gnl\|CDD\|181973
NC_003923.1\|WP_000182738.1\|291596_292511_-\|ribokinase	unknown	unknown	gnl\|CDD\|274000
NC_003923.1\|WP_000922317.1\|286940_287645_-\|GntR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|225099
NC_003923.1\|WP_000608831.1\|282167_282842_+\|iron-sulfur-cluster-repair-di-iron-protein-ScdA	unknown	unknown	gnl\|CDD\|183940
NC_003923.1\|WP_000029204.1\|292957_293839_-\|ribose-transporter-RbsU	unknown	unknown	gnl\|CDD\|284268
NC_003923.1\|WP_000607067.1\|286131_286833_+\|antiholin-like-protein-LrgB	unknown	unknown	gnl\|CDD\|179810
NC_003923.1\|WP_000950281.1\|283085_284840_+\|sensor-histidine-kinase	unknown	unknown	gnl\|CDD\|225814
NC_003923.1\|WP_000747873.1\|292538_292943_-\|D-ribose-pyranase	unknown	unknown	gnl\|CDD\|183318
NC_003923.1\|WP_001793213.1\|285695_286139_+\|antiholin-like-murein-hydrolase-modulator-LrgA	unknown	unknown	gnl\|CDD\|235222
NC_003923.1\|WP_000066930.1\|287793_288585_+\|PTS-glucose-transporter-subunit-IIA	unknown	unknown	gnl\|CDD\|225101
NC_003923.1\|WP_001159765.1\|295449_295842_+\|hypothetical-protein	unknown	unknown	unknown
NC_003923.1\|WP_000736792.1\|298897_299848_+\|glycine-glycine-endopeptidase-LytM	unknown	unknown	gnl\|CDD\|226451
NC_003923.1\|WP_000031274.1\|290584_291346_-\|class-I-SAM-dependent-methyltransferase	unknown	unknown	gnl\|CDD\|379312
NC_003923.1\|WP_000645456.1\|284842_285583_+\|DNA-binding-response-regulator	unknown	unknown	gnl\|CDD\|184495

Protein	Function_ID	Function_description	E-value
NC_003923.1\|WP_000240920.1\|278581_280270_+\|CDP-glycerol-glycerophosphotransferase-family-protein	gnl\|CDD\|367953	pfam04464, Glyphos_transf, CDP-Glycerol:Poly(glycerophosphate) glycerophosphotransferase. Wall-associated teichoic acids are a heterogeneous class of phosphate-rich polymers that are covalently linked to the cell wall peptidoglycan of gram-positive bacteria. They consist of a main chain of phosphodiester-linked polyols and/or sugar moieties attached to peptidoglycan via a linkage unit. CDP-glycerol:poly(glycerophosphate) glycerophosphotransferase is responsible for the polymerization of the main chain of the teichoic acid by sequential transfer of glycerol-phosphate units from CDP-glycerol to the linkage unit lipid.	4.42901e-119
NC_003923.1\|WP_000975365.1\|280302_282024_+\|poly(ribitol-phosphate)-beta-N-acetylglucosaminyltransferase	gnl\|CDD\|376098	pfam18674, TarS_C1, TarS beta-glycosyltransferase C-terminal domain 1. Beta-glycosyltransferase TarS is an enzyme responsible for the glycosylation of wall teichoic acid polymers of the S. aureus cell wall, a process that has been shown to be specifically responsible for methicillin resistance in MRSA. It contains a trimerization domain composed of tandem carbohydrate binding motifs.The two C-terminally localized regions composed of a series of beta-sheets participate in an extensive trimerization interface and they assume an immunoglobulin-like fold. It is suggested that both carbohydrate binding domains may be involved in polyRboP binding, however unlike pullulanase, the CBMs of TarS are involved in the formation of an extensive trimerization interface.	6.64158e-35
NC_003923.1\|WP_000757884.1\|294070_295069_-\|LacI-family-DNA-binding-transcriptional-regulator	gnl\|CDD\|224525	COG1609, PurR, Transcriptional regulators [Transcription].	2.77715e-100
NC_003923.1\|WP_001066553.1\|295969_297346_-\|MFS-transporter	gnl\|CDD\|129794	TIGR00711, Uncharacterized_MFS-type_transporter_YhcA, drug resistance transporter, EmrB/QacA subfamily. This subfamily of drug efflux proteins, a part of the major faciliator family, is predicted to have 14 potential membrane-spanning regions. Members with known activities include EmrB (multiple drug resistance efflux pump) in E. coli, FarB (antibacterial fatty acid resistance) in Neisseria gonorrhoeae, TcmA (tetracenomycin C resistance) in Streptomyces glaucescens, etc. In most cases, the efflux pump is described as having a second component encoded in the same operon, such as EmrA of E. coli. [Cellular processes, Toxin production and resistance, Transport and binding proteins, Other].	7.58117e-30
NC_003923.1\|WP_000337383.1\|297579_298572_+\|linear-amide-C-N-hydrolase	gnl\|CDD\|225591	COG3049, COG3049, Penicillin V acylase and related amidases [Cell envelope biogenesis, outer membrane].	5.1195e-152
NC_003923.1\|WP_000164010.1\|288600_290037_+\|6-phospho-beta-glucosidase	gnl\|CDD\|181973	PRK09589, celA, 6-phospho-beta-glucosidase; Reviewed.	0
NC_003923.1\|WP_000182738.1\|291596_292511_-\|ribokinase	gnl\|CDD\|274000	TIGR02152, Putative_ribokinase, ribokinase. This model describes ribokinase, an enzyme catalyzing the first step in ribose catabolism. The rbsK gene encoding ribokinase typically is found with ribose transport genes. Ribokinase belongs to the carbohydrate kinase pfkB family (pfam00294). In the wide gulf between the current trusted (360 bit) and noise (100 bit) cutoffs are a number of sequences, few of which are clustered with predicted ribose transport genes but many of which are currently annotated as if having ribokinase activity. Most likely some have this function and others do not. [Energy metabolism, Sugars].	4.25837e-143
NC_003923.1\|WP_000922317.1\|286940_287645_-\|GntR-family-transcriptional-regulator	gnl\|CDD\|225099	COG2188, PhnF, Transcriptional regulators [Transcription].	3.50966e-63
NC_003923.1\|WP_000608831.1\|282167_282842_+\|iron-sulfur-cluster-repair-di-iron-protein-ScdA	gnl\|CDD\|183940	PRK13276, PRK13276, iron-sulfur cluster repair di-iron protein ScdA.	7.18502e-154
NC_003923.1\|WP_000029204.1\|292957_293839_-\|ribose-transporter-RbsU	gnl\|CDD\|284268	pfam06800, Sugar_transport, Sugar transport protein. This is a family of bacterial sugar transporters approximately 300 residues long. Members include glucose uptake proteins, ribose transport proteins, and several putative and hypothetical membrane proteins probably involved in sugar transport across bacterial membranes. These members are transmembrane proteins which are usually 5+5 duplications. This model recognizes a set of five TMs,.	4.46997e-117
NC_003923.1\|WP_000607067.1\|286131_286833_+\|antiholin-like-protein-LrgB	gnl\|CDD\|179810	PRK04288, PRK04288, antiholin-like protein LrgB; Provisional.	5.86643e-124
NC_003923.1\|WP_000950281.1\|283085_284840_+\|sensor-histidine-kinase	gnl\|CDD\|225814	COG3275, LytS, Putative regulator of cell autolysis [Signal transduction mechanisms].	0
NC_003923.1\|WP_000747873.1\|292538_292943_-\|D-ribose-pyranase	gnl\|CDD\|183318	PRK11797, PRK11797, D-ribose pyranase; Provisional.	1.143e-69
NC_003923.1\|WP_001793213.1\|285695_286139_+\|antiholin-like-murein-hydrolase-modulator-LrgA	gnl\|CDD\|235222	PRK04125, PRK04125, antiholin-like protein LrgA.	4.17541e-63
NC_003923.1\|WP_000066930.1\|287793_288585_+\|PTS-glucose-transporter-subunit-IIA	gnl\|CDD\|225101	COG2190, NagE, Phosphotransferase system IIA components [Carbohydrate transport and metabolism].	3.3186e-53
NC_003923.1\|WP_000736792.1\|298897_299848_+\|glycine-glycine-endopeptidase-LytM	gnl\|CDD\|226451	COG3942, COG3942, Surface antigen [General function prediction only].	6.59985e-33
NC_003923.1\|WP_000031274.1\|290584_291346_-\|class-I-SAM-dependent-methyltransferase	gnl\|CDD\|379312	pfam13649, Methyltransf_25, Methyltransferase domain. This family appears to be a methyltransferase domain.	1.48144e-27
NC_003923.1\|WP_000645456.1\|284842_285583_+\|DNA-binding-response-regulator	gnl\|CDD\|184495	PRK14084, PRK14084, DNA-binding response regulator.	4.37999e-152

>NC_003923.1|WP_000164010.1|288600_290037_+|6-phospho-beta-glucosidase
MTKLPRNFMWGGALAANQFEGGYDKGGKGLSVIDVMTSGAHGKARQITKSIDQNHYYPNHEGIDFYHRYKEDIALFNEMGLKCLRTSIAWTRIFPNGDEDVPNEEGLAFYDRIFDELIAQDIEPVVTLSHFEMPLHLAKHYGGFRNREVVDYFVHFARVVFERYKDKVTYWMTFNEINNQMDTSNPIFLWTNSGVALTENDNPEEVLYQVAHHELLASALAVRLGKEINPKFKIGTMISHVPIYPYSCHPKDMMEAQIANRLRFFFPDVQVRGYYPSYAKKMLARKGYDVGWQEGDDSILQQGTVDYIGFSYYMSTAVKHDVDTTVENNIVNGGLNHSVENPHIATSDWGWAIDPDGLRYTLNVLYDRYQLPLFIVENGFGAVDEVVDGHIHDDYRIEYLKAHITAAIEAVDQDGVDLIGYTPWGIIDIVSFTTGEMKKRYGLIYVDRDNDGHGTMERLKKDSFYWYQQVIASNGDKL
>NC_003923.1|WP_000066930.1|287793_288585_+|PTS-glucose-transporter-subunit-IIA
MSNKYKEQAQDILTAVGGVENIVDATYDTKCITIHMQHTIPSTANEVKQIVDVTSVAENDAQLVIKLNGNVDEVYQQLQRLIKNANVEESENTDNINSQDTSYIPQVKVTTPILVKAPIAGRRILLKEVRDSIFREKMVGEGLAIKAHEESKVIAPFNGLISMIVPTKHAVRIQSEDGVDIVIHIGVNTVDLEGKGFKCFVKQNDRVEAGQTLLQFDQQYIQQQGYNADVIVVISNSADLGKVELTMNEIITTEDVIFKIFKN
>NC_003923.1|WP_000922317.1|286940_287645_-|GntR-family-transcriptional-regulator
MLKYEHIAKQLNAFIHQSKFKPGDKLPSVTQLKERYQVSKSTIIKALGLLEQDGLIYQAQGSGIYVRNIADANRINVFKTNGFSKSLGEHRMTSKVLVFKEMATPPKSVQDELQLNADDTVYYLERLRFVDDDVLCIEYSYYHKEIVKYLNDDIAKGSIFDYLESNMKLRIGFSDIFFNVDKLTSSEASLLQLSTGEPCLRYHQTFYTMTGKPFDSSDIVFHYRHAQFYIPSKK
>NC_003923.1|WP_000607067.1|286131_286833_+|antiholin-like-protein-LrgB
MINHLALNTPYFGILLSVIPFFLATILFEKTNRFFLFAPLFVSMVFGVAFLYLTGIPYKTYKIGGDIIYFFLEPATICFAIPLYKKREVLVKHWHRIIGGIGIGTVVALLIILTFAKLAQFANDVILSMLPQAATTAIALPVSAGIGGIKELTSLAVILNGVIIYALGNKFLKLFRITNPIARGLALGTSGHTLGVAPAKELGPVEESMASIALVLVGVVVVAVVPVFVAIFF
>NC_003923.1|WP_001793213.1|285695_286139_+|antiholin-like-murein-hydrolase-modulator-LrgA
MVVKQQKDASKPAHFFHQVIVIALVLFVSKIIESFMPIPMPGSVIGLVLLFVLLCTGAVKLGEVEKVGTTLTNNIGLLFVPAGISVVNSLGVISQAPFLIIGLIIVSTILLLICTGYVTQIIMKVTSRSKGDKVTKKIKIEEAQAHD
>NC_003923.1|WP_000645456.1|284842_285583_+|DNA-binding-response-regulator
MKALIIDDEPLARNELTYLLNEIGGFEEINEAENVKETLEALLINQYDIIFLDVNLMDENGIELGAKIQKMKEPPAIIFATAHDQYAVQAFELNATDYILKPFGQKRIEQAVNKVRATKAKDDNSASAIANDMSANFDQSLPVEIDDKIHMLKQQNIIGIGTHNGITTIHTTNHKYETTEPLNRYEKRLNPAYFIRIHRSYIINTKHIKEVQQWFNYTYMVILTNGVKMQVGRSFMKDFKASIGLL
>NC_003923.1|WP_000950281.1|283085_284840_+|sensor-histidine-kinase
MLSLTMLLLERVGLIIILAYVLMNIPYFKNLMNRRRTWKARWQLCIIFSLFALMSNLTGIVIDHQHSLSGSVYFRLDDDVSLANTRVLTIGVAGLVGGPFVGLFVGVISGIFRVYMGGADAQVYLISSIFIGIIAGYFGLQAQRRKRYPSIAKSAMIGIVMEMIQMLSILTFSHDKAYAVDLISLIALPMIIVNSVGTAIFMSIIISTLKQEEQMKAVQTHDVLQLMNQTLPYFKEGLNRESAQQIAMIIKNLMKVSAVAITSKNEILSHVGAGSDHHIPTNEILTSLSKDVLKSGKLKEVHTKEEIGCSHPNCPLRAAIVIPLEMHGSIVGTLKMYFTNPNDLTFVERQLAEGLANIFSSQIELGEAETQSKLLKDAEIKSLQAQVSPHFFFNSINTISALVRINSEKARELLLELSYFFRANLQGSKQHTITLDKELSQVRAYLSLEQARYPGRFNININVEDKYRDVLVPPFLIQILVENAIKHAFTNRKQGNDIDVSVIKETATHVRIIVQDNGQGISKDKMHLLGETSVESESGTGSALENLNLRLKGLFGKSAALQFESTSSGTTFWCVLPYERQEEE
>NC_003923.1|WP_000608831.1|282167_282842_+|iron-sulfur-cluster-repair-di-iron-protein-ScdA
MINKNDIVADVVTDYPKAADIFRSVGIDFCCGGQVSIEAASLEKKNVDLNELLQRLNDVEQTNTPGSLNPKFLNVSSLIQYIQAAYHEPLREEFKNLTPYVTKLSKVHGPNHPYLVELKETYDTFKNGMLEHMQKEDDVDFPKLIKYEQGEVVDDINTVIDDLVSDHIATGQLLVKMSDLTSSYEPPIEACGTWRLVYQRLKALEVLTHEHVHLENHVLFKKVS
>NC_003923.1|WP_000975365.1|280302_282024_+|poly(ribitol-phosphate)-beta-N-acetylglucosaminyltransferase
MMKFSVIVPTYNSEKYITELLNSLAKQDFPKTEFEVVVVDDCSTDQTLQIVEKYRNKLNLKVSQLETNSGGPGKPRNVALKQAEGEFVLFVDSDDYINKETLKDAAAFIDEHHSDVLLIKMKGVNGRGVPQSMFKETAPEVTLLNSRIIYTLSPTKIYRTTLLKDNDIYFPEELKSAEDQLFTMKAYLNANRISVLSDKAYYYATKREGEHMSSAYVSPEDFYEVMRLIAVEILNADLEEAHKDQILAEFLNRHFSFSRTNGFSLKVKLEDQPQWINALGDFIQAVPERVDALVMSKLRPLLHYARAKDIDNYRTVEESYRQGQYYRFDIVDGKLNIQFNEGEPYFEGIDIAKPKVKMTAFKFDNHKIVTELTLNEFMIGEGHYDVRLKLHSRNKKHTMYVPLSVNANKQYRFNIMLEDIKAYLPKEKIWDVFLEVQIGTEVFEVRVGNQRNKYAYTAETSALIHLNNDFYRLTPYFTKDFNNISLYFTAITLTDSISLKLKGKNKIILTGLDRGYVFEEGMASVVLKDDMIMGMLSQTSENEVEILLSKDIKKRDFKNIVKLNTAHMTYSLK
>NC_003923.1|WP_000240920.1|278581_280270_+|CDP-glycerol-glycerophosphotransferase-family-protein
MVKSKIYIDKIYWERVQLFVEGHSENLDLEDSNFVLRNLTETRTMKANDVKIDGNQFVCRFNVAILDNGYYLPEDKYLLVNEQELDYIAQLNPDVINDAYQNLKPEQEEEYNELETQNGKINFLLQTYLKEFRKGGISKKTVYTVTPEISSDVNEFVLDVVVTTPEVKSIYIVRKYKELRKYFRKQSFNTRQFIFKAIFNTTKFFHLKKGNTVLFTSDSRPTMSGNFEYIYNEMLRQNLDKKYDIHTVFKANITDRRGIIDKFRLPYLLGKADYIFVDDFHPLIYTVRFRRSQEVIQVWHAVGAFKTVGFSRTGKKGGPFIDSLNHRSYTKAYVSSETDIPFYAEAFGIKEKNVVPTGVPRTDVLFDEAYATQIKQEMEDELPIIKGKKVILFAPTFRGSGHGTAHYPFFKIDFERLARYCEKNNAVVLFKMHPFVKNRLNIADKHKQYFVDVSDFREVNDILFITDLLISDYSSLIYEYAVFKKPMIFYAFDLEDYITTRDFYEPYESFVPGKIVQSFDALMDALDNEDYEGEKVIPFLDKHFKYQDGRSSERLVRNLFGS
>NC_003923.1|WP_000031274.1|290584_291346_-|class-I-SAM-dependent-methyltransferase
MSKEAGHTFLAKLGKTRLRPGGKEATDWLIQQGAFSQDKQVLEVACNMCTTSIYLAHTYGCHIQGVDINKKALEKAQENISAAGLESYIQVQQANAVKLPFDDNQFDIVLNEAMLTMLPITIKEKALREYYRVLKPGGILLTHDIVIVNESHATHVVKSLSAAINVNVSPQTKLGWLDLYNQAGFNHVHYHTGPMSLMTPKGLIYDEGIVGTIKIINNALKKENRPMFCKMFKTMTKLRKDMNYITFVAKKED
>NC_003923.1|WP_001789860.1|291364_291499_+|hypothetical-protein
MIIIIINIAYLYAIIWKLKRLQKIVTSFITKHESTSIGLVENYF
>NC_003923.1|WP_000182738.1|291596_292511_-|ribokinase
MTNKVVILGSTNVDQFLTVERYAQPGETLHVEEAQKAFGGGKGANQAIATARMQADTTFITKIGTDGVADFILEDFKAAHIDTSYIIKSTEAKTGQAFITVNAEGQNTIYVYGGANMTMTPEDVINAKDAIINADFVVAQLEVPIPAIISAFEIAKAHGVTTVLNPAPAKALPNELLSLIDIIVPNETEAELLSGIKVTNEQSMKDNANYFLSLGIKTVLITLGKQGTYFATKNQSQHIEAYKVNAIDTTAAGDTFIGAFVSRLNKSQDNLADAIDFGNKASSLTVQKHGAQASIPLLEEVNQV
>NC_003923.1|WP_000747873.1|292538_292943_-|D-ribose-pyranase
MKKSAVLNEHISKAIATIGHFDLLTINDAGMPIPNDHRRIDLAVTKNLPRFIDVLATVLEEMEIQKIYLAEEIKEHNPTQLQQIKQLISSEIEIIFIPHEEMKSNLAHPLNKGNIRTGETTPYSNIALESNVTF
>NC_003923.1|WP_000029204.1|292957_293839_-|ribose-transporter-RbsU
MSIVALLIGLGPLIGWGFFPTVASKFGGKPVHQIIGATVGTLIFAIILAVVTSSGFPTGTNLLFALLSGAGWGFGQIITFKAFELVGSSRAMPVTTAFQLLGASLWGVFALGNWPGIGHKIIGFTALVVILIGARMTVWSERKEASNAKNLRRAVVLLLIGEFGYWLYSAAPQATSIDGLTAFLPQAMGMVIVAVIYGFMNMKAENPFRNKITWLQIISGFFFAFGALTYLISAQPNMNGLATGFILSQTSVVLATLTGIYFLKQHKTSKEMVITIIGLVLILVAASVTVFIK
>NC_003923.1|WP_000757884.1|294070_295069_-|LacI-family-DNA-binding-transcriptional-regulator
MKKVSIKDVAREAGVSVTTVSHILNHNDSRFSATTIKNVHAVSERLGYAPNKHAKQLRGSKIQTIGVILPSLTNPFFSALMQSIHDHKPSDVDLCFLTSTATDLYDNIKHLIDRGIDGLIIAQYISSPDALNNYLKKHHVPYVVLDQNDHQGYTDFVRTNEYQGGQLAAQHLIELGHNNMMIVAPYDMMANMSTRVAGFVDTLRANQLPEPQIVHTELSKRGGLTIVDDIMVQSATAIFAINDELAIGILRGLIEHGISIPKDISLIGYDDIDYAAYVSPPLTTVAQPITDIGKTSLTLLLQRLQHLDKSIDMIELPTTLKIRATTGYHLSN
>NC_003923.1|WP_001159765.1|295449_295842_+|hypothetical-protein
MQFKLKEEEIISFLELKYPEKEFEYGRLLVGQHKRDDLDVYYFGDTFLMCTIISFKTFEIKETVELSYDAVNRIVLKDGWLFRKMRIETMQKVLKYGTSKLMLTDFQKENYNKYIQGQKQRVIFENGHFV
>NC_003923.1|WP_001066553.1|295969_297346_-|MFS-transporter
MNNTQSSPRSNIIIAIMLSALTYWLFAQSFINIGPLVGQTYQTSPAVLNLSISLTSFATGIFMVAAGDIADKIGQLRMTYMGLIISMFASLLLIISDITALLIIGRILQGLSAAILLPSTVGVLNNQFKGEHLRRAISYLMISTVGGIGLAGVIGGLIATNFGWQTNFIISIVIAFIAILLLKGTPEKVSQHSHRHPFDYKGMSIFAVMIGSFTLLLTQGFEQGWFSTFSFICLSIFIITTLIFIIIERRHEVPFIDFSVLRNRPFIGAFLNNFVLNSGLGVTVVFFIYAQTHLGLSAAQSGLVTLPYAIVAVAMIRLGEKATLRFGGKLMLIIGPLFPVIGITIISMTQLSASQYVIAVIIGFVICAIGNGLVATPGLTIAIFSMPNEKVGLATGLYKMSGTLGGAFGIALSTTVFSMLQLNYAPSVAATVTFIVSIVLMILGSLSAYMIIPKTVKS
>NC_003923.1|WP_000337383.1|297579_298572_+|linear-amide-C-N-hydrolase
MCTGFTIQTLNNQVLLGRTMDYDYPLDGSPAVTPRNYRWTSRTGTTGQTQYGFIGTGTDMEGFIYGDGVNEHGVAISTQYFRGYSSYGSTHKAGAMNITQNEIVTWILGYTTSIEDMKQQASQIHVVAVYLNDIGEVPPLHYHVSDATGHSVEVSFKEGEVVIKDNPIGVLTNHPDLDWHYSNLRQYINISPYPATAKLLEGVTIEPLGNEAGTFGLPGGFTSTERFVRMAFMKANIAQNNDKEMDLMNAFYLLDAVNIPIGIVRPHDADNHYTMYQTVINLTTRTLYIKYYGSNELVALKLTDDLINRKDMTIFKPEKHITIRKLNDNQ
>NC_003923.1|WP_000736792.1|298897_299848_+|glycine-glycine-endopeptidase-LytM
MKKLTAAAIATMGFATFTMAHQADAAETTNTQQAHTQMSTQSQDVSYGTYYTIDSNGDYHHTPDGNWNQAMFDNKEYSYTFVDAQGHTHYFYNCYPKNANANGSGQTYVNPAIAGDNNDYTASQSQQHINQYGYQSNVGPDASYYSHSNNNQAYNSHDGNGKVNYPNGTSNQNGGLASKATASGHAKDASWLTSRKQLQPYGQYHGGGAHYGVDYAMPENSPVYSLTDGTVVQAGWSNYGGGNQVTIKEANSNNYQWYMHNNRLTVSAGDKVKAGDQIAYSGSTGNSTAPHVHFQRMSGGIGNQYAVDPTSYLQSR

You can click texts colored in the table to view more detailed information

Click the colored protein region to show detailed information

Crispr_ID: NC_003923_3

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_003923_3

656523-656611

Orphan

Consensus_repeat	Method
CTAAAGGTGAAGAGGAACGCAGTTGGAT	CRISPRCasFinder

1 spacers

The CRISPR arrays of NC_003923_3

>merge|NC_003923|3|656523-656611|CRISPRCasFinder
CTAAAGGTGAAGAGGAACGCAGTTGGATATTAAGGCACAACTGCATAAAAGCCTCTAATCACTAAAGGTGAAGAGGAACGCAGTTGGAT

>NC_003923|3|2|656523-656611|CRISPRCasFinder
CTAAAGGTGAAGAGGAACGCAGTTGGAT	ATTAAGGCACAACTGCATAAAAGCCTCTAATCA
CTAAAGGTGAAGAGGAACGCAGTTGGAT

Protein	Signature genes	Signature genes Name	Protein_function
NC_003923.1\|WP_001200748.1\|651984_652995_+\|alcohol-dehydrogenase-AdhP	unknown	unknown	gnl\|CDD\|181842
NC_003923.1\|WP_000359085.1\|653271_653688_+\|DUF1934-domain-containing-protein	unknown	unknown	gnl\|CDD\|226896
NC_003923.1\|WP_001788301.1\|664275_665205_-\|DMT-family-transporter	unknown	unknown	gnl\|CDD\|225778
NC_003923.1\|WP_000362978.1\|659426_660227_+\|alpha/beta-hydrolase	unknown	unknown	gnl\|CDD\|223669
NC_003923.1\|WP_000169042.1\|665399_665624_-\|DUF2922-domain-containing-protein	unknown	unknown	gnl\|CDD\|378571
NC_003923.1\|WP_000749057.1\|656682_657570_+\|ABC-transporter-substrate-binding-protein	unknown	unknown	gnl\|CDD\|238563
NC_003923.1\|WP_011053017.1\|657718_658669_+\|iron-ABC-transporter-permease	unknown	unknown	gnl\|CDD\|376439
NC_003923.1\|WP_000180230.1\|649641_650937_+\|HD-domain-containing-protein	unknown	unknown	gnl\|CDD\|224004
NC_003923.1\|WP_000655099.1\|653071_653179_+\|hypothetical-protein	unknown	unknown	unknown
NC_003923.1\|WP_000735558.1\|660362_660869_+\|hypothetical-protein	unknown	unknown	unknown
NC_003923.1\|WP_001021145.1\|653684_655346_+\|arginine--tRNA-ligase	unknown	unknown	gnl\|CDD\|234964
NC_003923.1\|WP_001045423.1\|661915_662704_+\|alpha/beta-hydrolase	unknown	unknown	gnl\|CDD\|223669
NC_003923.1\|WP_001222133.1\|661030_661747_+\|hypothetical-protein	unknown	unknown	unknown
NC_003923.1\|WP_000901765.1\|655736_656372_+\|endonuclease-III-domain-containing-protein	unknown	unknown	gnl\|CDD\|225140
NC_003923.1\|WP_000808902.1\|647271_648210_+\|aldo/keto-reductase	unknown	unknown	gnl\|CDD\|381309
NC_003923.1\|WP_000477504.1\|649125_649602_+\|GNAT-family-N-acetyltransferase	unknown	unknown	gnl\|CDD\|366181
NC_003923.1\|WP_000633782.1\|648420_648957_+\|flavodoxin-family-protein	unknown	unknown	gnl\|CDD\|223728
NC_003923.1\|WP_001018677.1\|662953_663328_-\|transcriptional-regulator	unknown	unknown	gnl\|CDD\|130944
NC_003923.1\|WP_001788287.1\|650964_651486_+\|YwhD-family-protein	unknown	unknown	gnl\|CDD\|378039
NC_003923.1\|WP_000365354.1\|658723_659443_+\|HAD-family-hydrolase	unknown	unknown	gnl\|CDD\|223943

Protein	Function_ID	Function_description	E-value
NC_003923.1\|WP_001200748.1\|651984_652995_+\|alcohol-dehydrogenase-AdhP	gnl\|CDD\|181842	PRK09422, PRK09422, ethanol-active dehydrogenase/acetaldehyde-active reductase; Provisional.	0
NC_003923.1\|WP_000359085.1\|653271_653688_+\|DUF1934-domain-containing-protein	gnl\|CDD\|226896	COG4506, COG4506, Uncharacterized protein conserved in bacteria [Function unknown].	6.64437e-58
NC_003923.1\|WP_000362978.1\|659426_660227_+\|alpha/beta-hydrolase	gnl\|CDD\|223669	COG0596, MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [General function prediction only].	2.45049e-26
NC_003923.1\|WP_000169042.1\|665399_665624_-\|DUF2922-domain-containing-protein	gnl\|CDD\|378571	pfam11148, DUF2922, Protein of unknown function (DUF2922). This bacterial family of proteins has no known function.	1.74707e-13
NC_003923.1\|WP_000749057.1\|656682_657570_+\|ABC-transporter-substrate-binding-protein	gnl\|CDD\|238563	cd01143, YvrC, Periplasmic binding protein YvrC. These proteins are predicted to function as initial receptors in ABC transport of metal ions in eubacteria and archaea. They belong to the TroA superfamily of periplasmic metal binding proteins that share a distinct fold and ligand binding mechanism. A typical TroA protein is comprised of two globular subdomains connected by a single helix and can bind the metal ion in the cleft between these domains.	5.51028e-73
NC_003923.1\|WP_011053017.1\|657718_658669_+\|iron-ABC-transporter-permease	gnl\|CDD\|376439	pfam01032, FecCD, FecCD transport family. This is a sub-family of bacterial binding protein-dependent transport systems family. This Pfam entry contains the inner components of this multicomponent transport system.	2.7531e-48
NC_003923.1\|WP_000180230.1\|649641_650937_+\|HD-domain-containing-protein	gnl\|CDD\|224004	COG1078, COG1078, HD superfamily phosphohydrolases [General function prediction only].	1.70707e-150
NC_003923.1\|WP_001045423.1\|661915_662704_+\|alpha/beta-hydrolase	gnl\|CDD\|223669	COG0596, MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [General function prediction only].	9.91231e-35
NC_003923.1\|WP_001788301.1\|664275_665205_-\|DMT-family-transporter	gnl\|CDD\|225778	COG3238, COG3238, Uncharacterized protein conserved in bacteria [Function unknown].	6.05558e-37
NC_003923.1\|WP_001021145.1\|653684_655346_+\|arginine--tRNA-ligase	gnl\|CDD\|234964	PRK01611, argS, arginyl-tRNA synthetase; Reviewed.	0
NC_003923.1\|WP_000901765.1\|655736_656372_+\|endonuclease-III-domain-containing-protein	gnl\|CDD\|225140	COG2231, COG2231, Uncharacterized protein related to Endonuclease III [DNA replication, recombination, and repair].	6.89847e-90
NC_003923.1\|WP_000808902.1\|647271_648210_+\|aldo/keto-reductase	gnl\|CDD\|381309	cd19083, AKR_AKR11A1_11D1, AKR11A and AKR11D families of aldo-keto reductase (AKR). Bacillus subtilis aldo-keto reductase IolS, also called vegetative protein 147 (VEG147), is a founding member of aldo-keto reductase family 11 member A1 (AKR11A1). It is able to reduce the standard aldo-keto reductase (AKR) substrates DL-glyceraldehyde, D-erythrose, and methylglyoxal in the presence of NADPH, albeit with poor efficiency in vitro. Bacillus aryabhattai aldo keto reductase is a founding member of aldo-keto reductase family 11 member D1 (AKR11D1).	7.3194e-168
NC_003923.1\|WP_000477504.1\|649125_649602_+\|GNAT-family-N-acetyltransferase	gnl\|CDD\|366181	pfam00583, Acetyltransf_1, Acetyltransferase (GNAT) family. This family contains proteins with N-acetyltransferase functions such as Elp3-related proteins.	1.13315e-11
NC_003923.1\|WP_000633782.1\|648420_648957_+\|flavodoxin-family-protein	gnl\|CDD\|223728	COG0655, WrbA, Multimeric flavodoxin WrbA [General function prediction only].	3.16348e-26
NC_003923.1\|WP_001018677.1\|662953_663328_-\|transcriptional-regulator	gnl\|CDD\|130944	TIGR01889, Pleiotropic_Regulator_Of_Virulence, staphylococcal accessory regulator family. This model represents a family of transcriptional regulatory proteins in Staphylococcus aureus and Staphylococcus epidermidis. Some members contain two tandem copies of this region. This family is related to the MarR transcriptional regulator family described by pfam01047. [Regulatory functions, DNA interactions].	1.77309e-26
NC_003923.1\|WP_001788287.1\|650964_651486_+\|YwhD-family-protein	gnl\|CDD\|378039	pfam08741, YwhD, YwhD family. This family of proteins are currently uncharacterized. They are around 170 amino acids in length.	8.7406e-98
NC_003923.1\|WP_000365354.1\|658723_659443_+\|HAD-family-hydrolase	gnl\|CDD\|223943	COG1011, COG1011, Predicted hydrolase (HAD superfamily) [General function prediction only].	3.6864e-38

>NC_003923.1|WP_000901765.1|655736_656372_+|endonuclease-III-domain-containing-protein
MLGTDELYKVLYEHLGPQFWWPADNDIEMMLGAILVQNTRWRNAEIALNQVKEHTHFNPNHILELPIETLQSLIHSSGFYKSKSLTIKTLLTWLARHHFNYQEINERYKGGLRKELLSLKGIGSETADVLLVYIFGRIEFIPDSYTRKIYDKLGYENTKNYDQLKKVVTLPNHFTNQDANEFHALLDVFGKHYFRDKDIKNYDFLEPYFKK
>NC_003923.1|WP_001021145.1|653684_655346_+|arginine--tRNA-ligase
MNIIDQVKQTLVEEIAASINKAGLADEIPDIKIEVPKDTKNGDYATNIAMVLTKIAKRNPREIAQAIVDNLDTEKAHVKQIDIAGPGFINFYLDNQYLTAIIPEAIEKGDQFGHVNESKGQNVLLEYVSANPTGDLHIGHARNAAVGDALANILTAAGYNVTREYYINDAGNQITNLARSIETRFFEALGDNSYSMPEDGYNGKDIIEIGKDLAEKHPEIKDYSEEARLKEFRKLGVEYEMAKLKNDLAEFNTHFDNWFSETSLYEKGEILEVLAKMKELGYTYEADGATWLRTTDFKDDKDRVLIKNDGTYTYFLPDIAYHFDKVKRGNDILIDLFGADHHGYINRLKASLETFGVDSNRLEIQIMQMVRLMENGKEVKMSKRTGNAITLREIMDEVGVDAARYFLTMRSPDSHFDFDMELAKEQSQDNPVYYAQYAHARICSILKQAKEQGIEVTAANDFTTITNEKAIELLKKVADFEPTIESAAEHRSAHRITNYIQDLASHFHKFYNAEKVLTDDIEKTKAHVAMIEAVRITLKNALAMVGVSAPESM
>NC_003923.1|WP_000359085.1|653271_653688_+|DUF1934-domain-containing-protein
MDKKVSIQTKQVLKQHNEKEKFEFTTEGTWQQRQSNFIRYVEQIEDATVNVTIKVDDDSVKLIRKGDINMNLHFVEGQTTTTFYDISAGRIPLDVKTLRILHFVSGDGGKLKIHYELYQDNEKMGSYQYEINYKEIGE
>NC_003923.1|WP_000655099.1|653071_653179_+|hypothetical-protein
MKDSENLVFFGFEVLFVFYKMAYIYEALIKYGIVN
>NC_003923.1|WP_001200748.1|651984_652995_+|alcohol-dehydrogenase-AdhP
MRAAVVTKDHKVSIEDKKLRALKPGEALVQTEYCGVCHTDLHVKNADFGDVTGVTLGHEGIGKVIEVAEDVESLKIGDRVSIAWMFESCGRCEYCTTGRETLCRSVKNAGYTVDGAMAEQVIVTADYAVKVPEKLDPAAASSITCAGVTTYKAVKVSNVKPGQWLGVFGIGGLGNLALQYAKNVMGAKIVAFDINDDKLAFAKELGADAIINSKDVDPVAEVMKLTDNKGLDATVVTSVAKTPFNQAVDVVKAGARVVAVGLPVDKMNLDIPRLVLDGIEVVGSLVGTRQDLREAFEFAAENKVTPKVQLRKLEEINDIFEEMENGTITGRMVIKF
>NC_003923.1|WP_001788287.1|650964_651486_+|YwhD-family-protein
MEVISLSEKKGFNFNIIKNDPLDGHKGTNIGSISLDNIAPVFIDVANKEAFIDIGGMHARAKVEKGVKWITDKAAVEGDEAKEYWLCWVTTERNEQGPYYAGLTACYLLVNKAIRRGYKSMPEHVNMMDKSMKHHIIIDQIGDENKAILKDFLMNHDEGMWKHSSDALHQAFN
>NC_003923.1|WP_000180230.1|649641_650937_+|HD-domain-containing-protein
MTNAYVDLKLVEEKVFKDPIHRYIHVEDQLIWDLIKTKEFQRLRRIRQLGTLYLSFHTAEHSRFGHSLGVYEIVRRLIDESFIGHDAWDNKDRPLALCAALLHDLGHGPFSHSFEKIFNTDHEAYTQAIITGDTEVNAVLRKVAPEFPREVAEVINKTHHNKLVISMISSQIDADRMDYLQRDAYFTGVSYGAFDMERILRLMRPSKDEVLIKESGMHAVENFIMSRYQMYWQIYFHPVSRGGEVLLNNCLKRAKQLYNEGYEFKLHPHDFIPFFEETVTIEQYVELDEAVVTYYLEKWTKEDDAILSDLASRFINRDLFKYIPFDGSIITISELQELFEAGGINPDYYFVSEAFSDLPYDYDRPGSNRKPIHLLRQDGTIREISNQSLVIHSITGINRQDYKLYYPREMVAKIKDKTIREAIENLINELN
>NC_003923.1|WP_000477504.1|649125_649602_+|GNAT-family-N-acetyltransferase
MFKVRQATEKDVVQIRDVATKAWFNTYLNIYAATTVNHLLEASYNEHHLKKRLQEQLFLVVEEGNDIVGFANFIYGEELYLSAHYVKPESQHTGYGTALLNEGLSRFEDKFEGVYLEVDNKNEEAVAYYKEQGFTILRSYEPEMYGEKLDLALMYKAF
>NC_003923.1|WP_000633782.1|648420_648957_+|flavodoxin-family-protein
MITVLFGGSRPNGNTAQLTKFALQDLEYQWIDVTQHQFKPIRDVRHTAETITSYDDDYLPILDKILASDTIIFASPVYWYSISAPLKAFIEHWSETLQDKRYPNFKAQMAEKDFRVILVGGDCPKIKAKPAITQMKYSLDFLGATLNGYIIGTAEKPGDIMKDNYALARATEWNSILQ
>NC_003923.1|WP_000808902.1|647271_648210_+|aldo/keto-reductase
MKQFVNLGKSDVEVFPIALGTNAVGGHNLYPNLDEEQGKDVVRQAINHGINLLDTAYIYGPERSEELVGEVVKEYPREQIKIATKGSHEFDENQEVHQNNQPEYLKQQVENSLKRLQTDYIDLYYIHFPDNNTPKDQAVAALQELKEQGKIKAIGVSNFTLDQLKEANKDGYVDVVQLEYNLLHRENEAVLQYCVDHQITFIPYFPLASGILAGKYDENTKFSDHRTTRRDFKPGVFEENVRRVKALESIAAAHQTSIANIVLAFYLTRPAIDVIIPGAKRAEQVVENIKAADIVLSDDEIQYIDELFPIED
>NC_003923.1|WP_000749057.1|656682_657570_+|ABC-transporter-substrate-binding-protein
MKKSLIAFILIFMLVLSGCGMKDNDKQGSNDNGSSKSPYHRIVSLMPSNTEILYELGLGKYIVGVSTVDDYPKDVKEGKKQFDALNLNKEELLKEKPDLILAHESQKATANKVLSSLEKQGIKVVYVKDAQSIDETYNTFKQIGKLTHHDKQAEQLVEETKDNIDKVIDSIPAHHKKSKVFIEVSSKPEIYTAGKHTFFNDMLEKLEAQNVYSDINGWNPVTKESIIKKNPDILISTEAKTRSDYMDIIKKRGGFNKINAVKNTRIEVVNGDEVSRPGPRIDEGLKELRDAIYRK
>NC_003923.1|WP_011053017.1|657718_658669_+|iron-ABC-transporter-permease
MTFNKVLLSWIVILIITTSIYLFWQLGDINDVFNQSILINVRLPRLLEALLTGMILTVAGLIFQTVLNNALADSFTLGLASGATFGSGLALFLGLTTLWIPVFSITFSLITLIIVLVITSVLSQGYPVRILILSGLMIGALFNSLLYFLILLKPRKLNTIANYLFGGFGDAEYSNVSIIAITFIIALFGIFIILNQLKLLQLGELKSQSLGLNVQLITYIALCIASMITAINVAYVGIIGFIGMVIPQLIRKWQWKQSLGRQLALNIVIGGQIMVMADFIGSHILSPVQIPASIIIALIGIPVLFYMLISQSKRLH
>NC_003923.1|WP_000365354.1|658723_659443_+|HAD-family-hydrolase
MDLNQIKAVVFDLEGTLLDRVKSREKFIEEQYERFHDYLIHVQLADFKKAFIELDDDEDNDKPDLYKEIIKRFHVDRLTWKDLFNDFEMHFYRYVFPYYDTLYTLEKLSQKGFQIGVIANGKSKIKQFRLHSLGLMHVINYLSTSETVGFRKPHPKIFEDMIDQLGVLPEQIMYVGDDALNDVAPARAMGMVSVWYKQEDAEIEPLEEEVDFTITTVEELLTILPIKNDNKGENYGSIY
>NC_003923.1|WP_000362978.1|659426_660227_+|alpha/beta-hydrolase
MDLFTRKDGTSIHYSTLGEGYPIVLIHTVLDNYSVFNKLAAQLAKSFQVVLIDLRGHGYSDKPRHIEIKDFSDDIVELLKYLYIEEVAFVCHEMGGIIGADISVRYPEFTSSLMLVNPTSIEGELPEERLFRKYAHIIRNWDPEKQDKFLNKRKYYRPRKMNRFLKHVVDTNEISTKEEIQAVKEVFKNADISQTYRNVVVPTKIIAGEFGERTTRLEAKEVADLIQNADFEVYQESSAFPFVEEQERFVEDTASFINKHHDEKHV
>NC_003923.1|WP_000735558.1|660362_660869_+|hypothetical-protein
MKKLLTASIIACSVVMGVGLVNTSAEAASGNSIDTVKQLIKGDQSLENVKIGESIKDVLTKYKNPMYSYNEDGTEHYYEFHTKKGMLLVTTDGKKNNGKVTHISMMYNDANGPTYQAVKNYVGKAVTHTEYSKVAGNFGYIEKGKTTYQFASAPKDKNIKLYRIDLEK
>NC_003923.1|WP_001222133.1|661030_661747_+|hypothetical-protein
MRINDKILLENIEDYFNHKGLSPHLIDDIKEKVITDIKNSEKKDQDYIEYKRKSPAQIILMIQRNLFALQMNPVIFFIINFILISYLYDKQYVQFQAITGMSLFYCLVIFPMTIVVYLRVSQKNYLRSNKIEMIMGTIIAIISLLLIILQAFNITWGVIPITNFGHQFFFFIGIILVIAGIFYKRLEFSGIGLLFCQKTVDAMIHNPQSAQIFSLIIWILLVVLVIYFTIRLSSRTRL
>NC_003923.1|WP_001045423.1|661915_662704_+|alpha/beta-hydrolase
MNKVTINPQIQLTYQIEGKGDPIILLHGLDGNLAGFEDLQHQLASSYKVLTYDLRGHGKSSKSESYDLNDHVEDLKILMEKLNIHEAHILGHDLGGVVAKLFTDKYAYRVKSLTTIASKKDDLIHSFTQLLIQYQDDIAGFNKSEAYILLFSKLFRNQEKTMKWYQKQRIYSIKSEDDSAVAIRSLILHKDEPMYLKKRTCVPTLLINGEHDPLIKDKNHFKLEAHFLNVTKKIFEHSGHAPHIEEPEAFMNYYLNFLKSVS
>NC_003923.1|WP_001018677.1|662953_663328_-|transcriptional-regulator
MAITKINDCFELLSMVTYADKLKSLIKKEFSISFEEFAVLTYISENKEKEYYLKDIINHLNYKQPQVVKAVKILSQEDYFDKKRNEHDERTVLILVNAQQRKKIESLLSRVNKRITEANNEIEL
>NC_003923.1|WP_001788301.1|664275_665205_-|DMT-family-transporter
MLLFYIIGVLVGMLIPIQTSVNSRLSLYTKSPFYTSFISFSVGTICLIILNIIINPEVFTIHFYNNQSFNYTWVVGGLLGVSFLTGNLLLLPKLGATLTVIATVAGQIIMGVIIDTFGLFGATIHDFNLIKAIGVLLLIVGIVIMNQFNKNNLLLTDQKYLLFWLLLGFIFGFFPPIQTTINSALASHTHSPAFASLVSFTIGSITLLILTAIFNRSLKLKTSHLKFGKLKPIYFTGGILGMAFVTANIILMPHMGAALTTLIGMFGQILMGILIDHFGLFGSPKIAMTSRKTIGLLCILTGIILLRLF
>NC_003923.1|WP_000169042.1|665399_665624_-|DUF2922-domain-containing-protein
MTKTLELSFKSSLDKPVKLQLPQLNNVVTEQVARDSMNALVDLNIIKSNSGTITKVHSAQIIDKTTTVLFEDKK

You can click texts colored in the table to view more detailed information

Click the colored protein region to show detailed information

Crispr_ID: NC_003923_4

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_003923_4

813797-813877

Unclear

Consensus_repeat	Method
TTCTTTATGTTGGGGCCCCGCCAACT	CRISPRCasFinder

1 spacers

The CRISPR arrays of NC_003923_4

>merge|NC_003923|4|813797-813877|CRISPRCasFinder
TTCTTTATGTTGGGGCCCCGCCAACTTGCATTGTTTGTAGAATTTCTTTTCGAAATTCTTTATGTTGGGGCCCCGCCAACT

>NC_003923|4|3|813797-813877|CRISPRCasFinder
TTCTTTATGTTGGGGCCCCGCCAACT	TGCATTGTTTGTAGAATTTCTTTTCGAAA
TTCTTTATGTTGGGGCCCCGCCAACT

Protein	Signature genes	Signature genes Name	Protein_function
NC_003923.1\|WP_000369722.1\|819597_820509_+\|RNase-adapter-RapZ	unknown	unknown	gnl\|CDD\|224574
NC_003923.1\|WP_000958224.1\|814113_815046_+\|HPr-kinase/phosphorylase	unknown	unknown	gnl\|CDD\|235459
NC_003923.1\|WP_001224793.1\|815898_816384_+\|acetyltransferase	unknown	unknown	gnl\|CDD\|100053
NC_003923.1\|WP_000513312.1\|815051_815891_+\|prolipoprotein-diacylglyceryl-transferase	unknown	unknown	gnl\|CDD\|183527
NC_003923.1\|WP_010956549.1\|804983_806094_+\|peptide-chain-release-factor-2	unknown	unknown	gnl\|CDD\|234799
NC_003923.1\|WP_000617735.1\|801151_801724_+\|ribosome-associated-translation-inhibitor-RaiA	unknown	unknown	gnl\|CDD\|224461
NC_003923.1\|WP_001790092.1\|804710_804815_+\|hypothetical-protein	unknown	unknown	unknown
NC_003923.1\|WP_000816305.1\|823958_824861_-\|TIGR01777-family-protein	unknown	unknown	gnl\|CDD\|224015
NC_003923.1\|WP_072360986.1\|806247_806355_+\|hypothetical-protein	unknown	unknown	unknown
NC_003923.1\|WP_000057543.1\|816391_817831_+\|tetratricopeptide-repeat-protein	unknown	unknown	gnl\|CDD\|276808
NC_003923.1\|WP_000229237.1\|808667_810653_+\|excinuclease-ABC-subunit-UvrB	unknown	unknown	gnl\|CDD\|235395
NC_003923.1\|WP_000753321.1\|806502_807342_+\|CHAP-domain-containing-protein	unknown	unknown	gnl\|CDD\|226451
NC_003923.1\|WP_001049165.1\|823128_823716_+\|ATP-dependent-Clp-endopeptidase-proteolytic-subunit-ClpP	unknown	unknown	gnl\|CDD\|178955
NC_003923.1\|WP_000506531.1\|802137_804669_+\|preprotein-translocase-subunit-SecA	unknown	unknown	gnl\|CDD\|237259
NC_003923.1\|WP_000006551.1\|821611_822556_+\|DNA-binding-protein-WhiA	unknown	unknown	gnl\|CDD\|273194
NC_003923.1\|WP_000662681.1\|810660_813507_+\|excinuclease-ABC-subunit-UvrA	unknown	unknown	gnl\|CDD\|234734
NC_003923.1\|WP_000538141.1\|807515_808166_+\|HD-domain-containing-protein	unknown	unknown	gnl\|CDD\|378993
NC_003923.1\|WP_000134963.1\|817897_818833_+\|thioredoxin-disulfide-reductase	unknown	unknown	gnl\|CDD\|273540
NC_003923.1\|WP_001248939.1\|820505_821501_+\|YvcK-family-protein	unknown	unknown	gnl\|CDD\|211689
NC_003923.1\|WP_000638419.1\|808162_808399_+\|CsbA-family-protein	unknown	unknown	gnl\|CDD\|227234

Protein	Function_ID	Function_description	E-value
NC_003923.1\|WP_000369722.1\|819597_820509_+\|RNase-adapter-RapZ	gnl\|CDD\|224574	COG1660, COG1660, Predicted P-loop-containing kinase [General function prediction only].	4.97899e-170
NC_003923.1\|WP_000958224.1\|814113_815046_+\|HPr-kinase/phosphorylase	gnl\|CDD\|235459	PRK05428, PRK05428, HPr kinase/phosphorylase; Provisional.	1.22623e-170
NC_003923.1\|WP_001224793.1\|815898_816384_+\|acetyltransferase	gnl\|CDD\|100053	cd04647, LbH_MAT_like, Maltose O-acyltransferase (MAT)-like: This family is composed of maltose O-acetyltransferase, galactoside O-acetyltransferase (GAT), xenobiotic acyltransferase (XAT) and similar proteins. MAT and GAT catalyze the CoA-dependent acetylation of the 6-hydroxyl group of their respective sugar substrates. MAT acetylates maltose and glucose exclusively while GAT specifically acetylates galactopyranosides. XAT catalyzes the CoA-dependent acetylation of a variety of hydroxyl-bearing acceptors such as chloramphenicol and streptogramin, among others. XATs are implicated in inactivating xenobiotics leading to xenobiotic resistance in patients. Members of this family contain a a left-handed parallel beta-helix (LbH) domain with at least 5 turns, each containing three imperfect tandem repeats of a hexapeptide repeat motif (X-[STAV]-X-[LIV]-[GAED]-X). They are trimeric in their active form.	4.85181e-30
NC_003923.1\|WP_000513312.1\|815051_815891_+\|prolipoprotein-diacylglyceryl-transferase	gnl\|CDD\|183527	PRK12437, PRK12437, prolipoprotein diacylglyceryl transferase; Reviewed.	4.82832e-120
NC_003923.1\|WP_010956549.1\|804983_806094_+\|peptide-chain-release-factor-2	gnl\|CDD\|234799	PRK00578, prfB, peptide chain release factor 2; Validated.	0
NC_003923.1\|WP_000617735.1\|801151_801724_+\|ribosome-associated-translation-inhibitor-RaiA	gnl\|CDD\|224461	COG1544, COG1544, Ribosome-associated protein Y (PSrp-1) [Translation, ribosomal structure and biogenesis].	1.13584e-37
NC_003923.1\|WP_000134963.1\|817897_818833_+\|thioredoxin-disulfide-reductase	gnl\|CDD\|273540	TIGR01292, Thioredoxin_reductase, thioredoxin-disulfide reductase. This model describes thioredoxin-disulfide reductase, a member of the pyridine nucleotide-disulphide oxidoreductases (pfam00070). [Energy metabolism, Electron transport].	4.19425e-154
NC_003923.1\|WP_000816305.1\|823958_824861_-\|TIGR01777-family-protein	gnl\|CDD\|224015	COG1090, COG1090, Predicted nucleoside-diphosphate sugar epimerase [General function prediction only].	1.79553e-154
NC_003923.1\|WP_000006551.1\|821611_822556_+\|DNA-binding-protein-WhiA	gnl\|CDD\|273194	TIGR00647, DNA_bind_WhiA, DNA-binding protein WhiA. This family describes a DNA-binding protein widely conserved in Gram-positive bacteria, and occasionally occurring elsewhere, such as in Thermotoga. It is associated with cell division, and in sporulating organisms with sporulation. [Cellular processes, Cell division].	7.40812e-153
NC_003923.1\|WP_000057543.1\|816391_817831_+\|tetratricopeptide-repeat-protein	gnl\|CDD\|276808	sd00008, TPR_YbbN, C-terminal Tetratricopeptide repeat (TPR) region of YbbN and similar motifs. The Tetratricopeptide repeat (TPR) typically contains 34 amino acids and is found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi, plants, and humans. It is present in a variety of proteins including those involved in chaperone, cell-cycle, transcription, and protein transport complexes. YbbN is a thioredoxin-like protein containing two tandem TPR repeats at the C-terminus, separated by two alpha helices. Its N-terminal thioredoxin-like domain is not a functional oxidoreductase. It functions in heat stress response and DNA synthesis as a chaperone or co-chaperone.	4.14043e-06
NC_003923.1\|WP_000229237.1\|808667_810653_+\|excinuclease-ABC-subunit-UvrB	gnl\|CDD\|235395	PRK05298, PRK05298, excinuclease ABC subunit UvrB.	0
NC_003923.1\|WP_000753321.1\|806502_807342_+\|CHAP-domain-containing-protein	gnl\|CDD\|226451	COG3942, COG3942, Surface antigen [General function prediction only].	1.82721e-42
NC_003923.1\|WP_001049165.1\|823128_823716_+\|ATP-dependent-Clp-endopeptidase-proteolytic-subunit-ClpP	gnl\|CDD\|178955	PRK00277, clpP, ATP-dependent Clp protease proteolytic subunit; Reviewed.	4.59321e-148
NC_003923.1\|WP_000506531.1\|802137_804669_+\|preprotein-translocase-subunit-SecA	gnl\|CDD\|237259	PRK12904, PRK12904, preprotein translocase subunit SecA; Reviewed.	0
NC_003923.1\|WP_000662681.1\|810660_813507_+\|excinuclease-ABC-subunit-UvrA	gnl\|CDD\|234734	PRK00349, uvrA, excinuclease ABC subunit UvrA.	0
NC_003923.1\|WP_000538141.1\|807515_808166_+\|HD-domain-containing-protein	gnl\|CDD\|378993	pfam12917, HD_2, HD containing hydrolase-like enzyme. This is a family of bacterial and archaeal hydrolases.	6.51021e-58
NC_003923.1\|WP_001248939.1\|820505_821501_+\|YvcK-family-protein	gnl\|CDD\|211689	TIGR01826, Putative_gluconeogenesis_factor, conserved hypothetical protein, cofD-related. This model represents a subfamily of conserved hypothetical proteins that forms a sister group to the family of CofD, (TIGR01819), LPPG:Fo 2-phospho-L-lactate transferase, an enzyme of cytochrome F420 biosynthesis. Both this family and TIGR01819 are within the scope of the pfam01933. [Hypothetical proteins, Conserved].	5.06652e-172
NC_003923.1\|WP_000638419.1\|808162_808399_+\|CsbA-family-protein	gnl\|CDD\|227234	COG4897, CsbA, Uncharacterized protein conserved in bacteria [Function unknown].	4.73465e-34

>NC_003923.1|WP_000662681.1|810660_813507_+|excinuclease-ABC-subunit-UvrA
MKEPSIVVKGARAHNLKDIDIELPKNKLIVMTGLSGSGKSSLAFDTIYAEGQRRYVESLSAYARQFLGQMDKPDVDTIEGLSPAISIDQKTTSKNPRSTVATVTEIYDYIRLLYARVGKPYCPNHNIEIESQTVQQMVDRIMELEARTKIQLLAPVIAHRKGSHEKLIEDIGKKGYVRLRIDGEIVDVNDVPTLDKNKNHTIEVVVDRLVVKDGIETRLADSIETALELSEGQLTVDVIDGEDLKFSESHACPICGFSIGELEPRMFSFNSPFGACPTCDGLGQKLTVDVDLVVPDKDKTLNEGAIEPWIPTSSDFYPTLLKRVCEVYKINMDKPFKKLTERQRDILLYGSGDKEIEFTFTQRQGGTRKRTMVFEGVVPNISRRFHESPSEYTREMMSKYMTELPCETCHGKRLSREALSVYVGGLNIGEVVEYSISQALNYYKNIDLSEQDQAIANQILKEIISRLTFLNNVGLEYLTLNRASGTLSGGEAQRIRLATQIGSRLTGVLYVLDEPSIGLHQRDNDRLINTLKEMRDLGNTLIVVEHDDDTMRAADYLVDIGPGAGEHGGQIVSSGTPQKVMKDKKSLTGQYLSGKKRIEVPEYRRPASDRKISIRGARSNNLKGVDVDIPLSIMTVVTGVSGSGKSSLVNEVLYKSLAQKINKSKVKPGLYDKIEGIDQLDKIIDIDQSPIGRTPRSNPATYTGVFDDIRDVFAQTNEAKIRGYQKGRFSFNVKGGRCEACKGDGIIKIEMHFLPDVYVPCEVCDGKRYNRETLEVTYKGKNIADILEMTVEEATQFFENIPKIKRKLQTLVDVGLGYVTLGQQATTLSGGEAQRVKLASELHKRSTGKSIYILDEPTTGLHVDDISRLLKVLNRLVENGDTVVIIEHNLDVIKTADYIIDLGPEGGSGGGTIVATGTPEDIAQTKSSYTGKYLKEVLERDKQNTEDK
>NC_003923.1|WP_000229237.1|808667_810653_+|excinuclease-ABC-subunit-UvrB
MVEHYPFKIHSDFEPQGDQPQAIEEIVEGIKAGKRHQTLLGATGTGKTFTMSNVIKEVGKPTLIIAHNKTLAGQLYSEFKEFFPENRVEYFVSYYDYYQPEAYVPSTDTFIEKDASINDEIDQLRHSATSALFERDDVIIIASVSCIYGLGNPEEYKDLVVSVRVGMEMDRSELLRKLVDVQYTRNDIDFQRGTFRVRGDVVEIFPASKEELCIRVEFFGDEIDRIREVNYLTGEVLKEREHFAIFPASHFVTREEKLKVAIERIEKELEERLKELRDENKLLEAQRLEQRTNYDLEMMREMGFCSGIENYSVHLTLRPLGSTPYTLLDYFGDDWLVMIDESHVTLPQVRGMYNGDRARKQVLVDHGFRLPSALDNRPLKFEEFEEKTKQLVYVSATPGPYEIEHTDKMVEQIIRPTGLLDPKIEVRPTENQIDDLLSEIQTRVERNERVLVTTLTKKMSEDLTTYMKEAGIKVNYLHSEIKTLERIEIIRDLRMGTYDVIVGINLLREGIDIPEVSLVVILDADKEGFLRSNRSLIQTIGRAARNDKGEVIMYADKMTDSMKYAIDETQRRREIQMKHNEKHGITPKTINKKIHDLISATVENDENNDKAQTVIPKKMTKKERQKTIDNIEKEMKQAAKDLDFEKATELRDMLFELKAEG
>NC_003923.1|WP_000638419.1|808162_808399_+|CsbA-family-protein
MIWYFSAAFFPCVLVVLFSVITRSKWVGTILTLILIGASIYKEYFHNEWIIFIDVVSLLAGYLIIDQLEFHKHQDEDR
>NC_003923.1|WP_000538141.1|807515_808166_+|HD-domain-containing-protein
MGVHQYFKRLSDMERLIRLPGKFKYFEHNVAAHSFKVTKIAQYLATVEEYHGRKINWKSLYEKALNHDFAEVFTGDIKTPVKYASSELKKLFSQVEEEMVETFIEEEIPLQYRDVYKQRLQEGKDDSLEGQILSVADKIDLLYETFGEIQKRNPEELFFEIYEMSLETIIQFDHLASVQDFINNIIPEMLTENFIPRTELRETTMNILNKRKEENE
>NC_003923.1|WP_000753321.1|806502_807342_+|CHAP-domain-containing-protein
MKKTLTVTVSSVLAFLALNNAAHAQQHGTQVKTPVQHNYVSNVQAQTQSPTTYTVVAGDSLYKIALEHHLTLNQLYSYNPGVTPLIFPGDVISLVPQNKVKQTKAVKTPVRKASQAKKVVKQPVQQASKKVVVKQAPKQAVAKTVNVAYKPAQVQKSVPTVPVAHNYNKSVANRGNLYAYGNCTYYAFDRRAQLGRSIGSLWGNANNWNYAAKVAGFKVDKTPEVGAIFQTAAGPYGHVGVVESVNPNGTITVSEMNYAGFNVKSSRTILNPGKYNYIH
>NC_003923.1|WP_072360986.1|806247_806355_+|hypothetical-protein
MYLLKQHMQCAFSNITYGDFQGIELIVENVLNYMV
>NC_003923.1|WP_010956549.1|804983_806094_+|peptide-chain-release-factor-2
MELSEIKRNIDKYNQDLTQIRGSLDLENKETNIQEYEEMMAEPNFWDNQTKAQDIIDKNNALKAIVNGYKTLQAEVDDMDATWDLLQEEFDEEMKEDLEQEVINFKAKVDEYELQLLLDGPHDANNAILELHPGAGGTESQDWANMLFRMYQRYCEKKGFKVETVDYLPGDEAGIKSVTLLIKGHNAYGYLKAEKGVHRLVRISPFDSSGRRHTSFASCDVIPDFNNDEIEIEINPDDITVDTFRASGAGGQHINKTESAIRITHHPSGIVVNNQNERSQIKNREAAMKMLKSKLYQLKLEEQAREMAEIRGEQKEIGWGSQIRSYVFHPYSMVKDHRTNEETGKVDAVMDGDIGPFIESYLRQTMSHD
>NC_003923.1|WP_001790092.1|804710_804815_+|hypothetical-protein
MLWEESFYFTSVKYFKKCEEVVKRCYVLSFKKSV
>NC_003923.1|WP_000506531.1|802137_804669_+|preprotein-translocase-subunit-SecA
MGFLSKILDGNNKEIKQLGKLADKVIALEEKTAILTDEEIRNKTKQFQTELADIDNVKKQNDYLDKILPEAYALVREGSKRVFNMTPYKVQIMGGIAIHKGDIAEMRTGEGKTLTATMPTYLNALAGRGVHVITVNEYLSSVQSEEMAELYNFLGLTVGLNLNSKTTEEKREAYAQDITYSTNNELGFDYLRDNMVNYSEDRVMRPLHFAIIDEVDSILIDEARTPLIISGEAEKSTSLYTQANVFAKMLKQDEDYKYDEKTKAVHLTEQGADKAERMFKVENLYDVQNVDVISHINTALRAHVTLQRDVDYMVVDGEVLIVDQFTGRTMPGRRFSEGLHQAIEAKEGVQIQNESKTMASITFQNYFRMYNKLAGMTGTAKTEEEEFRNIYNMTVTQIPTNKPVQRNDKSDLIYISQKGKFDAVVEDVVEKHKAGQPVLLGTVAVETSEYISNLLKKRGIRHDVLNAKNHEREAEIVAGAGQKGAVTIATNMAGRGTDIKLGEGVEELGGLAVIGTERHESRRIDDQLRGRSGRQGDKGDSRFYLSLQDELMIRFGSERLQKMMSRLGLDDSTPIESKMVSRAVESAQKRVEGNNFDARKRILEYDEVLRKQREIIYNERNSIIDEEDSSQVVDAMLRSTLQRSINYYINTADDEPEYQPFIDYINDIFLQEGDITEDDIKGKDAEDIFEVVWAKIEAAYQSQKDILEEQMNEFERMILLRSIDSHWTDHIDTMDQLRQGIHLRSYAQQNPLRDYQNEGHELFDIMMQNIEEDTCKFILKSVVQVEDNIEREKTTEFGEAKHVSAEDGKEKVKPKPIVKGDQVGRNDDCPCGSGKKFKNCHGK
>NC_003923.1|WP_000617735.1|801151_801724_+|ribosome-associated-translation-inhibitor-RaiA
MIRFEIHGDNLTITDAIRNYIEEKIGKLERYFNDVPNAVAHVKVKTYSNSATKIEVTIPLKNVTLRAEERNDDLYAGIDLINNKLERQVRKYKTRINRKSRDRGDQEVFVAELQEMQETQVDNDAYDDNEIEIIRSKEFSLKPMDSEEAVLQMNLLGHDFFVFTDRETDGTSIVYRRKDGKYGLIQTSEQ
>NC_003923.1|WP_000958224.1|814113_815046_+|HPr-kinase/phosphorylase
MLTTEKLVETLKLDLIAGEEGLSKPIKNADISRPGLEMAGYFSHYASDRIQLLGTTELSFYNLLPDKDRAGRMRKLCRPETPAIIVTRGLQPPEELVEAAKELNTPLIVAKDATTSLMSRLTTFLEHALAKTTSLHGVLVDVYGVGVLITGDSGIGKSETALELVKRGHRLVADDNVEIRQINKDELIGKPPKLIEHLLEIRGLGIINVMTLFGAGSILTEKRIRLNINLENWNKQKLYDRVGLNEETLSILDTEITKKTIPVRPGRNVAVIIEVAAMNYRLNIMGINTAEEFSERLNEEIIKNSHKSEE
>NC_003923.1|WP_000513312.1|815051_815891_+|prolipoprotein-diacylglyceryl-transferase
MGIVFNYIDPVAFNLGPLSVRWYGIIIAVGILLGYFVAQRALVKAGLHKDTLVDIIFYSALFGFIAARIYFVIFQWPYYVENPSEIIKIWHGGIAIHGGLIGGFIAGVIVCKVKNLNPFQIGDIVAPSIILAQGIGRWGNFMNHEAHGGPVSRAFLEKLHLPNFIIENMYINGQYYHPTFLYESIWDVAGFIILVNIRKHLKLGETFFLYLTWYSIGRFFIEGLRTDSLMLTSNIRVAQLVSILLILISISLIVYRRIKYNPPLYSKVGALPWPTKKVK
>NC_003923.1|WP_001224793.1|815898_816384_+|acetyltransferase
MRKFLSKTHHHTNPLWRVYRLVKFSKVFKNVIIIEFSKFIPSMVLKRHIYKQLLNINIGNQSSIAYKVMLDIFYPELITIGSNSVIGYNVTILTHEALVDEFRYGPVTIGSNTLIGANATILPGITIGDNVKVAAGTVVSKDIPDNGFAYGNPMYIKMIRR
>NC_003923.1|WP_000057543.1|816391_817831_+|tetratricopeptide-repeat-protein
MAQKNNNVIPMTFDDAFYRKMAKQKFKQREYKRAAEYFEKVLELSPDDLEIQIDYAQCLVQLGIAKKAEHLFYDNIIYNRHLEDSFYELSQLNIEVNEPNKAFLFGINYVIVSDDQDYRDELDQMFDVKYQSEEQIELEAQLFVVQILFQYLFSQGRLKDAKNYVLHQPQEVQDHRVVRNLLAMCYLYLGEYDTAKALYEALLQEDSTDIYALCHYTLLLYNTKENEQYQKYLKILNKVVPMNDDESFKLGIVLSYLKQYRASQQLLYPLYKKGKFLSIQMYNALAYNYYYLGEEDESHYYWDKLKQISKVEIGHAPWVIENSKEVFDQHILPLLQSDDSHYRLYGIFLLDQLNGKEIVMTESIWQVLENLNNYEKLYLTYLVQGLTLNKLDFIHRGLLTLYQNELFVSENDLMVAWINQGELIIAEKVDLTDVEPYIGAFIYLYFKNQPRNVTKKQITTWLGITQYKLNKMIEFLLSI
>NC_003923.1|WP_000134963.1|817897_818833_+|thioredoxin-disulfide-reductase
MTEIDFDIAIIGAGPAGMTAAVYASRANLKTVMIERGIPGGQMANTEEVENFPGFEMITGPDLSTKMFEHAKKFGAVYQYGDIKSVEDKGEYKVINFGNKELTAKAVIIATGAEYKKIGVPGEQELGGRGVSYCAVCDGAFFKNKRLFVIGGGDSAVEEGTFLTKFADKVTIVHRRDELRAQRILQDRAFKNDKIDFIWSHTLKSINEKDGKVGSVTLTSTKDGSEETHEADGVFIYIGMKPLTAPFKDLGITNDVGYIVTKDDMTTSVPGIFAAGDVRDKGLRQIVTATGDGSIAAQSAAEYIEHLNDQA
>NC_003923.1|WP_000369722.1|819597_820509_+|RNase-adapter-RapZ
MDNNEKEKSKSELLVVTGLSGAGKSLVIQCLEDMGYFCVDNLPPVLLPKFVELMEQGNPSLRKVAIAIDLRGKELFNSLVAVVDKVKSESDVIIDVMFLEASTEKLISRYKETRRAHPLMEQGKRSLINAINDEREHLSQIRSIANFVIDTTKLSPKELKERIRRYYEDEEFETFTINVTSFGFKHGIQMDADLVFDVRFLPNPYYVVDLRPLTGLDKDVYNYVMKWKETEIFFEKLTDLLDFMIPGYKKEGKSQLVIAIGCTGGQHRSVALAERLGNYLNEVFEYNVYVHHRDAHIESGEKK
>NC_003923.1|WP_001248939.1|820505_821501_+|YvcK-family-protein
MRQIKVVLIGGGTGLSVMARGLREFPIDITAIVTVADNGGSTGKIRDEMDIPAPGDIRNVIAALSDSESVLSQLFQYRFEENQISGHSLGNLLIAGMTNITNDFGHAIKALSKILNIKGRVIPSTNTSVQLNAVMEDGEIVFGETNIPKKHKKIDRVFLEPNDVQPMEEAIDALREADLIVLGPGSLYTSVISNLCVNGISDALIHSDAPKLYVSNVMTQPGETDGYSVKDHIDAIHRQAGQPFIDYVICSTQTFNAQVLKKYEEKHSKPVEVNKAELEKESINVKTSSNLVEISENHLVRHNTKVLSTMIYDIALELISTIPFVPSDKRK
>NC_003923.1|WP_000006551.1|821611_822556_+|DNA-binding-protein-WhiA
MSFASEMKNELTRIDVDEMNAKAELSALIRMNGALSLSNQQFVINVQTENATTARRIYSLIKRVFNVEVEILVRKKMKLKKNNIYICRTKMKAKEILDELGILKDGIFTHEIDHSMIQDDEMRRSYLRGAFLAGGSVNNPETSSYHLEIFSQNESHAEGLTKLMNSYELNAKHLERKKGSITYLKEAEKISDFLSLIGGYQALLKFEDVRIVRDMRNSVNRLVNCETANLNKTVSAAMKQVESIKLIDKEIGIENLPDRLREIARIRVEHQEISLKELGEMVSTGPISKSGVNHRLRKLNDLADKIRNGEQIEL
>NC_003923.1|WP_001049165.1|823128_823716_+|ATP-dependent-Clp-endopeptidase-proteolytic-subunit-ClpP
MNLIPTVIETTNRGERAYDIYSRLLKDRIIMLGSQIDDNVANSIVSQLLFLQAQDSEKDIYLYINSPGGSVTAGFAIYDTIQHIKPDVQTICIGMAASMGSFLLAAGAKGKRFALPNAEVMIHQPLGGAQGQATEIEIAANHILKTREKLNRILSERTGQSIEKIQKDTDRDNFLTAEEAKEYGLIDEVMVPETK
>NC_003923.1|WP_000816305.1|823958_824861_-|TIGR01777-family-protein
MKQYLITGGTGMVGSQLVNEIKKSDSHITILTRHDQISNDKKISYVNWAKSGWEHKVPQNIDVVINLAGATLNKRWTPEYKQTLMLSRIQSTQALYELFKSRNKAPKVLFNASATGYYPPDLFMSYTEVYKTLPFDFLSDIVYQWERFAQQFEQLGTRVVIGRFGMILSNEGGALQTMKLPYKYYIGGRLGSGQQWYSWIHINDLIQAILFLINNESASGPFNLTAPIPERQNLFGYTLARAMHKPHETWAPSLAMRLILGQMSTVVLDTQKVLPNKIQALGFQFKYSNLKMALEDLIKE

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Crispr_ID: NC_003923_5

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_003923_5

875680-875761

Orphan

Consensus_repeat	Method
CCCCAACTTGCATTGTCTGTAGAA	CRISPRCasFinder

1 spacers

The CRISPR arrays of NC_003923_5

>merge|NC_003923|5|875680-875761|CRISPRCasFinder
CCCCAACTTGCATTGTCTGTAGAAATTGAGAATCCAATTTCTCTTTGTTGGGGCCCATCCCCAACTTGCATTGCCTGTAGAA

>NC_003923|5|4|875680-875761|CRISPRCasFinder
CCCCAACTTGCATTGTCTGTAGAA	ATTGAGAATCCAATTTCTCTTTGTTGGGGCCCAT
CCCCAACTTGCATTGCCTGTAGAA

Protein	Signature genes	Signature genes Name	Protein_function
NC_003923.1\|WP_000589549.1\|873624_873981_+\|arsenate-reductase-family-protein	unknown	unknown	gnl\|CDD\|239334
NC_003923.1\|WP_001140696.1\|868783_869365_+\|histidine-phosphatase-family-protein	unknown	unknown	gnl\|CDD\|223483
NC_003923.1\|WP_001183858.1\|880574_881426_-\|DUF368-domain-containing-protein	unknown	unknown	gnl\|CDD\|224946
NC_003923.1\|WP_000932228.1\|874697_875576_+\|DUF1963-domain-containing-protein	unknown	unknown	gnl\|CDD\|226395
NC_003923.1\|WP_000569884.1\|870209_870704_-\|GNAT-family-N-acetyltransferase	unknown	unknown	gnl\|CDD\|372596
NC_003923.1\|WP_000422910.1\|872471_873011_+\|nitroreductase	unknown	unknown	gnl\|CDD\|380312
NC_003923.1\|WP_000255544.1\|869437_870055_-\|amino-acid-transporter	unknown	unknown	gnl\|CDD\|224198
NC_003923.1\|WP_001018962.1\|876316_876703_+\|topiosmerase	unknown	unknown	gnl\|CDD\|224572
NC_003923.1\|WP_000150012.1\|871672_872389_+\|type-I-3-dehydroquinate-dehydratase	unknown	unknown	gnl\|CDD\|184156
NC_003923.1\|WP_000974464.1\|871102_871525_-\|organic-hydroperoxide-resistance-protein	unknown	unknown	gnl\|CDD\|274649
NC_003923.1\|WP_000732326.1\|878972_879794_+\|MetQ/NlpA-family-ABC-transporter-substrate-binding-protein	unknown	unknown	gnl\|CDD\|224381
NC_003923.1\|WP_001065801.1\|876695_876992_+\|thioredoxin-family-protein	unknown	unknown	gnl\|CDD\|239245
NC_003923.1\|WP_000571218.1\|877241_878267_+\|methionine-ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|224058
NC_003923.1\|WP_000520233.1\|878259_878955_+\|ABC-transporter-permease	unknown	unknown	gnl\|CDD\|224922
NC_003923.1\|WP_000290489.1\|874138_874519_+\|glycine-cleavage-system-protein-GcvH	unknown	unknown	gnl\|CDD\|234918
NC_003923.1\|WP_000205570.1\|882612_883920_+\|Fe-S-cluster-assembly-protein-SufD	unknown	unknown	gnl\|CDD\|223791
NC_003923.1\|WP_000752917.1\|880147_880342_+\|CsbD-family-protein	unknown	unknown	gnl\|CDD\|225777
NC_003923.1\|WP_000168845.1\|881753_882515_+\|Fe-S-cluster-assembly-ATPase-SufC	unknown	unknown	gnl\|CDD\|223473
NC_003923.1\|WP_001006454.1\|884025_885276_+\|cysteine-desulfurase	unknown	unknown	gnl\|CDD\|131034
NC_003923.1\|WP_001147953.1\|873160_873481_-\|thioredoxin-family-protein	unknown	unknown	gnl\|CDD\|239245

Protein	Function_ID	Function_description	E-value
NC_003923.1\|WP_000589549.1\|873624_873981_+\|arsenate-reductase-family-protein	gnl\|CDD\|239334	cd03036, ArsC_like, Arsenate Reductase (ArsC) family, unknown subfamily; uncharacterized proteins containing a CXXC motif with similarity to thioredoxin (TRX)-fold arsenic reductases, ArsC. Proteins containing a redox active CXXC motif like TRX and glutaredoxin (GRX) function as protein disulfide oxidoreductases, altering the redox state of target proteins via the reversible oxidation of the active site dithiol. ArsC catalyzes the reduction of arsenate [As(V)] to arsenite [As(III)], using reducing equivalents derived from glutathione via GRX, through a single catalytic cysteine.	1.06191e-56
NC_003923.1\|WP_001140696.1\|868783_869365_+\|histidine-phosphatase-family-protein	gnl\|CDD\|223483	COG0406, phoE, Broad specificity phosphatase PhoE and related phosphatases [General function prediction only].	1.48716e-48
NC_003923.1\|WP_001183858.1\|880574_881426_-\|DUF368-domain-containing-protein	gnl\|CDD\|224946	COG2035, COG2035, Predicted membrane protein [Function unknown].	4.58436e-76
NC_003923.1\|WP_000932228.1\|874697_875576_+\|DUF1963-domain-containing-protein	gnl\|CDD\|226395	COG3878, COG3878, Uncharacterized protein conserved in bacteria [Function unknown].	5.66518e-74
NC_003923.1\|WP_000569884.1\|870209_870704_-\|GNAT-family-N-acetyltransferase	gnl\|CDD\|372596	pfam13420, Acetyltransf_4, Acetyltransferase (GNAT) domain.	2.53639e-47
NC_003923.1\|WP_000422910.1\|872471_873011_+\|nitroreductase	gnl\|CDD\|380312	cd02135, YdjA-like, nitroreductase family protein similar to Escherichia coli YdjA. A subfamily of the nitroreductase family containing uncharacterized proteins that are similar to nitroreductase YdjA from Escherichia coli. Nitroreductase catalyzes the reduction of nitroaromatic compounds such as nitrotoluenes, nitrofurans and nitroimidazoles. This process requires NAD(P)H as electron donor in an obligatory two-electron transfer and uses FMN as cofactor. The enzyme is typically a homodimer. Members of this family are also called NADH dehydrogenase, oxygen-insensitive NAD(P)H nitrogenase or dihydropteridine reductase.	1.62265e-48
NC_003923.1\|WP_000255544.1\|869437_870055_-\|amino-acid-transporter	gnl\|CDD\|224198	COG1279, COG1279, Lysine efflux permease [General function prediction only].	1.6558e-60
NC_003923.1\|WP_001018962.1\|876316_876703_+\|topiosmerase	gnl\|CDD\|224572	COG1658, COG1658, Small primase-like proteins (Toprim domain) [DNA replication, recombination, and repair].	2.45102e-36
NC_003923.1\|WP_000150012.1\|871672_872389_+\|type-I-3-dehydroquinate-dehydratase	gnl\|CDD\|184156	PRK13575, PRK13575, type I 3-dehydroquinate dehydratase.	1.05028e-146
NC_003923.1\|WP_000974464.1\|871102_871525_-\|organic-hydroperoxide-resistance-protein	gnl\|CDD\|274649	TIGR03561, organ_hyd_perox, peroxiredoxin, Ohr subfamily. pfam02566, OsmC-like protein, contains several deeply split clades of homologous proteins. The clade modeled here includes the protein Ohr, or organic hydroperoxide resistance protein. [Cellular processes, Detoxification].	1.70812e-60
NC_003923.1\|WP_000732326.1\|878972_879794_+\|MetQ/NlpA-family-ABC-transporter-substrate-binding-protein	gnl\|CDD\|224381	COG1464, NlpA, ABC-type metal ion transport system, periplasmic component/surface antigen [Inorganic ion transport and metabolism].	2.15951e-112
NC_003923.1\|WP_001065801.1\|876695_876992_+\|thioredoxin-family-protein	gnl\|CDD\|239245	cd02947, TRX_family, TRX family; composed of two groups: Group I, which includes proteins that exclusively encode a TRX domain; and Group II, which are composed of fusion proteins of TRX and additional domains. Group I TRX is a small ancient protein that alter the redox state of target proteins via the reversible oxidation of an active site dithiol, present in a CXXC motif, partially exposed at the protein's surface. TRX reduces protein disulfide bonds, resulting in a disulfide bond at its active site. Oxidized TRX is converted to the active form by TRX reductase, using reducing equivalents derived from either NADPH or ferredoxins. By altering their redox state, TRX regulates the functions of at least 30 target proteins, some of which are enzymes and transcription factors. It also plays an important role in the defense against oxidative stress by directly reducing hydrogen peroxide and certain radicals, and by serving as a reductant for peroxiredoxins. At least two major types of functional TRXs have been reported in most organisms; in eukaryotes, they are located in the cytoplasm and the mitochondria. Higher plants contain more types (at least 20 TRX genes have been detected in the genome of Arabidopsis thaliana), two of which (types f amd m) are located in the same compartment, the chloroplast. Also included in the alignment are TRX-like domains which show sequence homology to TRX but do not contain the redox active CXXC motif. Group II proteins, in addition to either a redox active TRX or a TRX-like domain, also contain additional domains, which may or may not possess homology to known proteins.	7.01368e-14
NC_003923.1\|WP_000571218.1\|877241_878267_+\|methionine-ABC-transporter-ATP-binding-protein	gnl\|CDD\|224058	COG1135, AbcC, ABC-type metal ion transport system, ATPase component [Inorganic ion transport and metabolism].	3.37873e-170
NC_003923.1\|WP_000520233.1\|878259_878955_+\|ABC-transporter-permease	gnl\|CDD\|224922	COG2011, AbcD, ABC-type metal ion transport system, permease component [Inorganic ion transport and metabolism].	9.67625e-100
NC_003923.1\|WP_000290489.1\|874138_874519_+\|glycine-cleavage-system-protein-GcvH	gnl\|CDD\|234918	PRK01202, PRK01202, glycine cleavage system protein GcvH.	2.95269e-69
NC_003923.1\|WP_000205570.1\|882612_883920_+\|Fe-S-cluster-assembly-protein-SufD	gnl\|CDD\|223791	COG0719, SufB, Cysteine desulfurase activator SufB [Posttranslational modification, protein turnover, chaperones].	9.26601e-136
NC_003923.1\|WP_000752917.1\|880147_880342_+\|CsbD-family-protein	gnl\|CDD\|225777	COG3237, COG3237, Uncharacterized protein conserved in bacteria [Function unknown].	5.95583e-07
NC_003923.1\|WP_000168845.1\|881753_882515_+\|Fe-S-cluster-assembly-ATPase-SufC	gnl\|CDD\|223473	COG0396, sufC, Cysteine desulfurase activator ATPase [Posttranslational modification, protein turnover, chaperones].	1.29081e-150
NC_003923.1\|WP_001006454.1\|884025_885276_+\|cysteine-desulfurase	gnl\|CDD\|131034	TIGR01979, Probable_cysteine_desulfurase, cysteine desulfurases, SufSfamily. This model represents a subfamily of NifS-related cysteine desulfurases involved in FeS cluster formation needed for nitrogen fixation among other vital functions. Many cysteine desulfurases are also active as selenocysteine lyase and/or cysteine sulfinate desulfinase. This subfamily is associated with the six-gene SUF system described in E. coli and Erwinia as an FeS cluster formation system during oxidative stress. The active site Cys is this subfamily resembles GHHC with one or both His conserved. [Biosynthesis of cofactors, prosthetic groups, and carriers, Other].	0
NC_003923.1\|WP_001147953.1\|873160_873481_-\|thioredoxin-family-protein	gnl\|CDD\|239245	cd02947, TRX_family, TRX family; composed of two groups: Group I, which includes proteins that exclusively encode a TRX domain; and Group II, which are composed of fusion proteins of TRX and additional domains. Group I TRX is a small ancient protein that alter the redox state of target proteins via the reversible oxidation of an active site dithiol, present in a CXXC motif, partially exposed at the protein's surface. TRX reduces protein disulfide bonds, resulting in a disulfide bond at its active site. Oxidized TRX is converted to the active form by TRX reductase, using reducing equivalents derived from either NADPH or ferredoxins. By altering their redox state, TRX regulates the functions of at least 30 target proteins, some of which are enzymes and transcription factors. It also plays an important role in the defense against oxidative stress by directly reducing hydrogen peroxide and certain radicals, and by serving as a reductant for peroxiredoxins. At least two major types of functional TRXs have been reported in most organisms; in eukaryotes, they are located in the cytoplasm and the mitochondria. Higher plants contain more types (at least 20 TRX genes have been detected in the genome of Arabidopsis thaliana), two of which (types f amd m) are located in the same compartment, the chloroplast. Also included in the alignment are TRX-like domains which show sequence homology to TRX but do not contain the redox active CXXC motif. Group II proteins, in addition to either a redox active TRX or a TRX-like domain, also contain additional domains, which may or may not possess homology to known proteins.	7.31384e-24

>NC_003923.1|WP_000932228.1|874697_875576_+|DUF1963-domain-containing-protein
MLNIQDVSHLSKKEQKAYNRFVESVENGNLPVLPCIEMVLKEMKEETLNQSKIGGMPFLKSFKDIPLDENNVPMVLLAQINLDNLPEQQELFPVKEGILQFWISSEDQMYGMSENLKGNNINSRLVYIKEPITDLSLENIQAHLKSLDADNEDIPFSGAFSIEFRLSKQTITCTDYKYDEDVLALWNKVNPSFALKSMFGGYDELMEPVCNTFTAKEPFNQLGGYPYFDQIDPRTNDQELKMYDRVLLQIDSTRDGNSSIIWGDLGIANILVKSTDLEAMKFDDYMYSWDCS
>NC_003923.1|WP_000290489.1|874138_874519_+|glycine-cleavage-system-protein-GcvH
MAVPNELKYSKEHEWVKVEGNVATIGITEYAQSELGDIVFVELPETDDEINEGDTFGSVESVKTVSELYAPISGKVVEVNEELEDSPEFVNESPYEKAWMVKVEISDESQIEALLTAEKYSEMIGE
>NC_003923.1|WP_000589549.1|873624_873981_+|arsenate-reductase-family-protein
MIKFYQYKNCTTCKKAAKFLDEYGVSYEPIDIVQHTPTINEFKTIIANTGVEINKLFNTHGAKYRELDLKNKLQTLSDDEKLELLSSDGMLVKRPLAVMGDKITLGFKEDQYKETWLA
>NC_003923.1|WP_001147953.1|873160_873481_-|thioredoxin-family-protein
MQAIKSNESFKSVINSDTPVIVKFEAGWCPDCRAMDLWIDPIVEQYKDYQWYTVNRDELEDVVVENEVMGIPSLLVFKNGDKIAHLHSANAKSPEQVESFLAETFK
>NC_003923.1|WP_000422910.1|872471_873011_+|nitroreductase
MELQQAIANRRSVKKFKRDMHIDDALLYQAIEKAADAPNHGMREPWRVVHVPKDRLGDMSKDISKFAFPNELDKQQCHYDAVTKLGGMLLLILKTDPRQRQNDENYFAFGAYAQNLMLLLYEAGIGTCWKSPLYIYDPKVRKTLGIKKDEVLSGFLYLTDLEEDMPKAPRKNRNLITLY
>NC_003923.1|WP_000150012.1|871672_872389_+|type-I-3-dehydroquinate-dehydratase
MTHVEVVATIAPQLSIEETLIQKINHRIDAIDVLELRIDQIENVTVDQVAEMITKLKVMQDSFKLLVTYRTKLQGGYGQFINDLYLNLISDLANINGIDMIDIEWQADIDIEKHQRIITHLQQYNKEVVISHHNFESTPPLDELQFIFFKMQKFNPEYVKLAVMPHNKNDVLNLLQAMSTFSDTMDCKVVGISMSKLGLISRTAQGVFGGALTYGCIGEPQAPGQIDVTDLKAQVTLY
>NC_003923.1|WP_000974464.1|871102_871525_-|organic-hydroperoxide-resistance-protein
MAIHYETKATNVGGRKGHVYTDDRALDIDIVSPAQADGKATNPEQLFAAGYASCFNGAFDLILKQNKVRDAHPEVTLTVRLEDDSDSESPKLSVSIDATIKNVISQEEAEKYLQMAHEFCPYSKATQGNINVDLNVNVVD
>NC_003923.1|WP_000569884.1|870209_870704_-|GNAT-family-N-acetyltransferase
MIEIKTLTNNDFNEYKRLVSTVNEEFTQDSHYSQTMTDTLIHDILNQGSPKCIVFGCYENETLIATAALEQIRYVGKEHKSLIKYNFVTNNDKSINSELINFIINYARQNNYESLLTSIVSNNIGAKVFYSALGFDILGFEKNAIKIGNTYFDEHWLFYDLINK
>NC_003923.1|WP_000255544.1|869437_870055_-|amino-acid-transporter
MVTAIIHGFILAIGLILPLGAQNVFIFNQGANQPKYRYVLPAIIAAGLSDSLLIIIAVVGVSIIIMSLPVLQAIIYIVGLIFLMYMAWTIWHDKPSTDGEAQIMSPMKQVSFALSVSLLNPHAILDTIGVIGSSAALYSGSNKIAFTIACISVSWLWFFLLAILGEMVGSIDKTGKLLTIINKLSSIIIIIVALMILQKLIQLLF
>NC_003923.1|WP_001140696.1|868783_869365_+|histidine-phosphatase-family-protein
MAKTLYLMRHGQTLFNFKGLIQGFGDSPLTELGIAQAQKARSYYETKGINFDLYASSTQERASDTLENVAPNQSYQRFKGLKEWHFGLFEGESVYLFDNLYKPEDLFGDRIVPFKGEARQQVEDRIVKTLHDIMSQTKNNALVVSHGTIMGVFLRYCLKLDEALKHNIGNCNILKFEYDNGTFKFVELIDPNL
>NC_003923.1|WP_001018962.1|876316_876703_+|topiosmerase
MAIVNKVIIVEGKSDKKRVQQVIAEPVNIICTHGTMSIDKLDDMIESLYDKQVFVLADSDDEGDRIRNWFKRYLSESEHIFIDKTYCQVANCPKQYLAHVLSKHGFTCKKETPLLPNINNERLVLVNE
>NC_003923.1|WP_001065801.1|876695_876992_+|thioredoxin-family-protein
MNNSLDIKDVTTFYEEDKHLIFGYTPTCGTCKVSERMLDIANEILQLPLLKIDLNFYPQFCKDMQIMSTPILLLMNKDKEVKRIYAFKSVTDLLENLK
>NC_003923.1|WP_000571218.1|877241_878267_+|methionine-ABC-transporter-ATP-binding-protein
MIELKEVVKEYRTKNKEVLAVDHVNLSIRAGSIYGVIGFSGAGKSTLIRMFNHLEAPTSGEVIIDGDHIGQLSKNGLRAKRQKVSMIFQHFNLLWSRTVLKNIMFPLEIAGVPRRRAKQKALELVELVGLKGREKAYPSELSGGQKQRVGIARALANDPTVLLCDEATSALDPQTTDEILDLLLKIREQQNLTIVLITHEMHVIRRICDEVAVMESGKVIEQGPVTQVFENPQHTVTKRFVKDDLNDDFETSLTELEPLEKDAYIVRLVFAGSTTTEPIVSSLSTAYDIKINILEANIKNTKNGTVGFLVLHIPYISSVDFGKFEKELIERQVKMEVLRHG
>NC_003923.1|WP_000520233.1|878259_878955_+|ABC-transporter-permease
MGKSFSEIINEMITMPNIQWPEVWTAIVETLYMTVVSTIFAFILGLILGVLLFLSAKGKSIGARLFYSIVSFIVNLFRAIPFIILILLLIPFTSLILGTISGPTGALPALIIGAAPFYARLVEIAFKEIDKGVIEAAWSMGANTWTVIRKVLLPEAMPALVSGITVTAIALVGSTAVAGVIGAGGLGNLAYLTGFTRNQNDVILVSTVFILIIVFIIQFIGDWLTNKLDKR
>NC_003923.1|WP_000732326.1|878972_879794_+|MetQ/NlpA-family-ABC-transporter-substrate-binding-protein
MKKLFGLILVLTFAVVLAACGNGNKSGSDDKKITVGASPAPHAEILEKAKPLLEKKGYELDIKTINDYTTPNKLLDKGEIDANYFQHTPYLNTEKKDKGYKIVSAGDVHLEPMAVYSKKYKSLKELPKGATVYVSNNPAEQGRFLKFFVDAGLIKIKKGVKIEDAKFSDITENKKDIKFNNKQSAEFLPKIYQNEDADAVIINSNFAIEQKLNPKKDSIAVESAKDNPYANLIAVKEGHQDDKKIKALIEVLQSKDIQDFINEKYNGAVIPAK
>NC_003923.1|WP_000752917.1|880147_880342_+|CsbD-family-protein
MADESKFEQAKGNVKETVGNVTDNKNLENEGKEDKASGKAKEFVENAKEKATDFIDKVKGNKGE
>NC_003923.1|WP_001183858.1|880574_881426_-|DUF368-domain-containing-protein
MQQFKWINILKGFAMGTSDLVPGVSGGTIALLLGIYNQFIASISGIFSRRFWPSFTFLIPIIIGMLLAMGSLSNLFNYLLSQHHIPTMFFFGGLIIGIVPYLLKISNYKTSFTTKHYMMVIAGIAILIVITLMNNGDKHAGETLTLSTSLIIKYFIAGMCASSAMLLPGISGSFMLLVFGVYGTVMLAISEVVKLNFAGLPILLAVGFGVLAGFIISSKIIQYFLTHHKLMTFALIIGFVVGSLFAVFPGLPTNIVMWFVSLVVFIIGFIVSLTLGRITAENE
>NC_003923.1|WP_000168845.1|881753_882515_+|Fe-S-cluster-assembly-ATPase-SufC
MASTLEIKDLHVSIEDKEILKGVNLTINTDEIHAIMGPNGTGKSTLSSAIMGHPSYEVTKGEVLLDGVNILELEVDERAKAGLFLAMQYPSEITGVTNADFMRSAINAKREEGQEINLMQFIKKLDKNMDFLDIDKDMAQRYLNEGFSGGEKKRNEILQLMMLEPKFAILDEIDSGLDIDALKVVSKGINQMRGENFGALMITHYQRLLNYITPDKVHVMYAGKVVKSGGPELAKRLEEEGYEWVKEEFGSAE
>NC_003923.1|WP_000205570.1|882612_883920_+|Fe-S-cluster-assembly-protein-SufD
MTTDILNISEEQLVDYSKAHNEPSWMTELRKKALKLTETLEMPKPDKTKLRKWDFDSFKQHDVKGDVYQSLSQLPESVREIIDVDHSKNLVIQHNNTIAYTQVDDNASKDGVIVEGLADALMNHSDLVQKYFMKDAVTVDEHRITALHTALVNGGVFVYVPKNVVVEHPVQYVVLHDDENASFYNHVIIVTEESAEVTYVENYLSNASGEGNQLNIISEVIAGANSNITYGSVDYMDKGFTGHIIRRGITEADASINWALGLMNEGSQIIDNTTNLFGDRSTSSLKSVVIGTGEQKINLTSKIVQYGKETDGYILKHGVMKEHASSVFNGIGYIKHGGTKSIANQESRVLMLSEHARGDANPILLIDEDDVQAGHAASVGRVDPDQLYYLMSRGISQREAERLVIHGFLDPVVRELPIEDVKRQLREVIERKVSK
>NC_003923.1|WP_001006454.1|884025_885276_+|cysteine-desulfurase
MNEVAEHSFDVNEVIKDFPILDQKVNGKRLAYLDSTATSQTPVQVLNVLEDYYKRYNSNVHRGVHTLGSLATDGYENARETVRRFINAKYFEEIIFTRGTTASINLVAHSYGDANVEEGDEIVVTEMEHHANIVPWQQLAKRKNATLKFIPMTADGELNIEDIKQTINDKTKIVAIAHISNVLGTINDVKTIAEIAHQHGAIISVDGAQAAPHMKLDMQEMNADFYSFSGHKMLGPTGIGVLFGKRELLQKMEPIEFGGDMIDFVSKYDATWADLPTKFEAGTPLIAQAIGLAEAIRYLERIGFDAIHKYEQELTIYAYEQMSAIEGIEIYGPPKDRRAGVITFNLQDVHPHDVATAVDTEGVAVRAGHHCAQPLMKWLNVSSTARASFYIYNTKEDVDQLINALKQTKEFFSYEF

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Crispr_ID: NC_003923_6

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_003923_6

1698537-1698622

Orphan

Consensus_repeat	Method
TCTGTGTTGGGGCCCCATCCCCAACTT	CRISPRCasFinder

1 spacers

The CRISPR arrays of NC_003923_6

>merge|NC_003923|6|1698537-1698622|CRISPRCasFinder
TCTGTGTTGGGGCCCCATCCCCAACTTGCACATTATTGAAATCTGACTTTTGGTCAGCTTCTGTGTTGGGGCCCCGTCCCCAACTT

>NC_003923|6|5|1698537-1698622|CRISPRCasFinder
TCTGTGTTGGGGCCCCATCCCCAACTT	GCACATTATTGAAATCTGACTTTTGGTCAGCT
TCTGTGTTGGGGCCCCGTCCCCAACTT

Protein	Signature genes	Signature genes Name	Protein_function
NC_003923.1\|WP_000734072.1\|1692103_1694734_-\|alanine--tRNA-ligase	unknown	unknown	gnl\|CDD\|234701
NC_003923.1\|WP_000682646.1\|1705037_1705811_-\|tRNA-threonylcarbamoyladenosine-dehydratase	unknown	unknown	gnl\|CDD\|224100
NC_003923.1\|WP_000044799.1\|1706271_1708038_-\|aspartate--tRNA-ligase	unknown	unknown	gnl\|CDD\|234775
NC_003923.1\|WP_000752909.1\|1702813_1702996_-\|CsbD-family-protein	unknown	unknown	gnl\|CDD\|225777
NC_003923.1\|WP_000134779.1\|1691025_1691334_-\|DUF1292-domain-containing-protein	unknown	unknown	gnl\|CDD\|184235
NC_003923.1\|WP_000066094.1\|1698804_1699923_-\|tRNA-2-thiouridine(34)-synthase-MnmA	unknown	unknown	gnl\|CDD\|234664
NC_003923.1\|WP_001283308.1\|1695076_1697554_-\|ATP-dependent-RecD-like-DNA-helicase	unknown	unknown	gnl\|CDD\|273632
NC_003923.1\|WP_000426912.1\|1691780_1692041_-\|IreB-family-regulatory-phosphoprotein	unknown	unknown	gnl\|CDD\|180108
NC_003923.1\|WP_000939059.1\|1691348_1691777_-\|Holliday-junction-resolvase-RuvX	unknown	unknown	gnl\|CDD\|223886
NC_003923.1\|WP_001790559.1\|1705810_1705939_-\|hypothetical-protein	unknown	unknown	unknown
NC_003923.1\|WP_000137775.1\|1689176_1690100_-\|U32-family-peptidase	unknown	unknown	gnl\|CDD\|223896
NC_003923.1\|WP_000848309.1\|1687896_1689165_-\|U32-family-peptidase	unknown	unknown	gnl\|CDD\|223896
NC_003923.1\|WP_000567030.1\|1697555_1698224_-\|tetratricopeptide-repeat-protein	unknown	unknown	gnl\|CDD\|276809
NC_003923.1\|WP_000009238.1\|1702627_1702774_-\|hypothetical-protein	unknown	unknown	unknown
NC_003923.1\|WP_000102740.1\|1703602_1704877_+\|replication-associated-recombination-protein-A	unknown	unknown	gnl\|CDD\|237355
NC_003923.1\|WP_000985895.1\|1701377_1702391_+\|LLM-class-flavin-dependent-oxidoreductase	unknown	unknown	gnl\|CDD\|274646
NC_003923.1\|WP_000342266.1\|1690102_1690741_-\|O-methyltransferase	unknown	unknown	gnl\|CDD\|226607
NC_003923.1\|WP_000409158.1\|1699923_1701066_-\|cysteine-desulfurase	unknown	unknown	gnl\|CDD\|224029
NC_003923.1\|WP_000648617.1\|1687273_1687897_-\|uridine-kinase	unknown	unknown	gnl\|CDD\|235492
NC_003923.1\|WP_000704122.1\|1703095_1703518_-\|Rrf2-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|224870

Protein	Function_ID	Function_description	E-value
NC_003923.1\|WP_000734072.1\|1692103_1694734_-\|alanine--tRNA-ligase	gnl\|CDD\|234701	PRK00252, alaS, alanyl-tRNA synthetase; Reviewed.	0
NC_003923.1\|WP_000682646.1\|1705037_1705811_-\|tRNA-threonylcarbamoyladenosine-dehydratase	gnl\|CDD\|224100	COG1179, COG1179, Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1 [Coenzyme metabolism].	1.59061e-126
NC_003923.1\|WP_000044799.1\|1706271_1708038_-\|aspartate--tRNA-ligase	gnl\|CDD\|234775	PRK00476, aspS, aspartyl-tRNA synthetase; Validated.	0
NC_003923.1\|WP_000752909.1\|1702813_1702996_-\|CsbD-family-protein	gnl\|CDD\|225777	COG3237, COG3237, Uncharacterized protein conserved in bacteria [Function unknown].	4.22501e-07
NC_003923.1\|WP_000134779.1\|1691025_1691334_-\|DUF1292-domain-containing-protein	gnl\|CDD\|184235	PRK13678, PRK13678, hypothetical protein; Provisional.	1.28539e-26
NC_003923.1\|WP_000066094.1\|1698804_1699923_-\|tRNA-2-thiouridine(34)-synthase-MnmA	gnl\|CDD\|234664	PRK00143, mnmA, tRNA-specific 2-thiouridylase MnmA; Reviewed.	0
NC_003923.1\|WP_001283308.1\|1695076_1697554_-\|ATP-dependent-RecD-like-DNA-helicase	gnl\|CDD\|273632	TIGR01448, recD_rel, helicase, putative, RecD/TraA family. This model describes a family similar to RecD, the exodeoxyribonuclease V alpha chain of TIGR01447. Members of this family, however, are not found in a context of RecB and RecC and are longer by about 200 amino acids at the amino end. Chlamydia muridarum has both a member of this family and a RecD. [Unknown function, Enzymes of unknown specificity].	0
NC_003923.1\|WP_000426912.1\|1691780_1692041_-\|IreB-family-regulatory-phosphoprotein	gnl\|CDD\|180108	PRK05473, IreB-like, IreB family regulatory phosphoprotein. IreB (EF1202) was characterized in Enterococcus faecalis as a small protein, well-conserved in the Firmicutes. It belongs to a system that includes the Ser/Thr protein kinase IreK, and phosphatase IreP, undergoes phosphorylation on threonine residues, and is involved in regulating cephalosporin resistance. This family was previously named DUF965 by Pfam model pfam06135.	3.05024e-47
NC_003923.1\|WP_000939059.1\|1691348_1691777_-\|Holliday-junction-resolvase-RuvX	gnl\|CDD\|223886	COG0816, COG0816, Predicted endonuclease involved in recombination (possible Holliday junction resolvase in Mycoplasmas and B. subtilis) [DNA replication, recombination, and repair].	3.40149e-56
NC_003923.1\|WP_000137775.1\|1689176_1690100_-\|U32-family-peptidase	gnl\|CDD\|223896	COG0826, COG0826, Collagenase and related proteases [Posttranslational modification, protein turnover, chaperones].	4.87045e-104
NC_003923.1\|WP_000848309.1\|1687896_1689165_-\|U32-family-peptidase	gnl\|CDD\|223896	COG0826, COG0826, Collagenase and related proteases [Posttranslational modification, protein turnover, chaperones].	1.93695e-148
NC_003923.1\|WP_000567030.1\|1697555_1698224_-\|tetratricopeptide-repeat-protein	gnl\|CDD\|276809	sd00006, TPR, Tetratricopeptide repeat. The Tetratricopeptide repeat (TPR) typically contains 34 amino acids and is found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi, plants, and humans. It is present in a variety of proteins including those involved in chaperone, cell-cycle, transcription, and protein transport complexes. The number of TPR motifs varies among proteins. Those containing 5-6 tandem repeats generate a right-handed helical structure with an amphipathic channel that is thought to accommodate an alpha-helix of a target protein. It has been proposed that TPR proteins preferentially interact with WD-40 repeat proteins, but in many instances several TPR-proteins seem to aggregate to multi-protein complexes.	5.22121e-16
NC_003923.1\|WP_000102740.1\|1703602_1704877_+\|replication-associated-recombination-protein-A	gnl\|CDD\|237355	PRK13342, PRK13342, recombination factor protein RarA; Reviewed.	0
NC_003923.1\|WP_000985895.1\|1701377_1702391_+\|LLM-class-flavin-dependent-oxidoreductase	gnl\|CDD\|274646	TIGR03558, oxido_grp_1, luciferase family oxidoreductase, group 1. The Pfam domain family pfam00296 is named for luciferase-like monooxygenases, but the family also contains several coenzyme F420-dependent enzymes. This protein family represents a well-resolved clade within family pfam00296 and shows no restriction to coenzyme F420-positive species, unlike some other clades within pfam00296. [Unknown function, Enzymes of unknown specificity].	1.49102e-173
NC_003923.1\|WP_000342266.1\|1690102_1690741_-\|O-methyltransferase	gnl\|CDD\|226607	COG4122, COG4122, Predicted O-methyltransferase [General function prediction only].	1.23148e-73
NC_003923.1\|WP_000409158.1\|1699923_1701066_-\|cysteine-desulfurase	gnl\|CDD\|224029	COG1104, NifS, Cysteine sulfinate desulfinase/cysteine desulfurase and related enzymes [Amino acid transport and metabolism].	0
NC_003923.1\|WP_000648617.1\|1687273_1687897_-\|uridine-kinase	gnl\|CDD\|235492	PRK05480, PRK05480, uridine/cytidine kinase; Provisional.	5.13835e-138
NC_003923.1\|WP_000704122.1\|1703095_1703518_-\|Rrf2-family-transcriptional-regulator	gnl\|CDD\|224870	COG1959, COG1959, Predicted transcriptional regulator [Transcription].	5.58388e-46

>NC_003923.1|WP_000567030.1|1697555_1698224_-|tetratricopeptide-repeat-protein
MIDQQTIYQYIQNGKIEEALQALFGNIEENPTIIENYINAGIVLADANEIEKAERFFQKALTIDPKNGVVFYNLANVYYNQQRYQEAIKLYQQALQTEIEQVDCNYMIGMAFNQLESFKLALPYLMTAAELDKDKDAEVQFQYGLVLCQLEMFNEAITQLKHVLTIDKNHVDARYNLGLALFMKNEDIDEAITHFKEAVTIDPKHLLSQHALKTFTKMKEEE
>NC_003923.1|WP_001283308.1|1695076_1697554_-|ATP-dependent-RecD-like-DNA-helicase
MSDPTLFDYSMIKGTVEAILFQNSDNFYTVLKVDTIETNEDFDTMPTVVGFLPNIVEGDVYTFKGQVVDHPRYGKQLKAETFEKEMPQTKEAIISYLSSDLFKGVGKKTAQNIVNTLGDNAINDILDDHSVLEKVSGLSKKKQKQIAEQISANQESEKIMIRLHDLGFGPKLSMAIYQFYLGDTLTILDRNPYQLIYDIKGIGFNKADQLARNIGIAYNDNERLKAALLYTLEEECIKQGHTYLPINVVIDLTVDVLNYQDEEVIEPEKLDEMLQYLNEEKRLIIDNEQVAIPSLYYSEIKSVQNLFRIKTHTNKLTEIEQSDLQMHIGEIEDANQVNYAASQKEALQTAINSKVMLLTGGPGTGKTTVIKGIVELYAEIHGLSLDYDDYVNDDYPVVLAAPTGRASKRLQESTGLEAMTIHRLIGWNQDTKPEDILENEINARLIIIDEMSMVDTWLFHQFLSAVPLDAQLIFVGDEDQLPSVGPGQVFKDLIESKAIPRVNLTEVYRQQDGSSIIELAHRMKLGQKIDITQRFHDRSFINCQANQIPTVVEKVVTSAVNKGYTMADIQVLAPMYKGNAGIKRLNQVLQDILNPKKKDTREIEFGDVVFRKGDKVLQLVNRPNDNIFNGDIGVIVGIFWAKENALNKDVLVVDFEGNEITFTKQDMMELTHAYCTSIHKSQGSEFPIVIMPIVKQYFRMLQRPILYTGLTRAKMSLVLLGDPEAFDIGLKTNGQARLTQLCTLLKNYFNSEDEEMLENTATNDTGASQTTIDDQVEAPMSSNDSGEVTSDSTKTDINVLTEATMFKIDPMINMGEITPYDFIER
>NC_003923.1|WP_000734072.1|1692103_1694734_-|alanine--tRNA-ligase
MKKLKASEIRQKYLDFFVEKGHMVEPSAPLVPIDDDTLLWINSGVATLKKYFDGRETPKKPRIVNSQKAIRTNDIENVGFTARHHTFFEMLGNFSIGDYFKQEAIEFAWEFLTSDKWMGMEPDKLYVTIHPEDMEAYNIWHKDIGLEESRIIRIEGNFWDIGEGPSGPNTEIFYDRGEAYGQDDPAEEMYPGGENERYLEVWNLVFSEFNHNKDHSYTPLPNKNIDTGMGLERMASVSQNVRTNYETDLFMPIMNEIEKVSGKQYLVNNEQDVAFKVIADHIRTIAFAISDGALPANEGRGYVLRRLLRRAVRFSQTLGINEPFMYKLVDIVADIMEPYYPNVKEKADFIKRVIKSEEERFHETLEDGLAILNELIKKAKATTNEINGKDAFKLYDTYGFPIELTEEIAVQAGLKVDMTTFESEMQQQRDRARQARQNSQSMQVQSEVLKNITSASTFVGYDTATAQTTLTHLIYNGEEVSQVEAGETVYFMLTETPFYAVSGGQVADTGIVYNDNFEIAVSEVTKAPNGQNLHKGVVQFGQVNVGATVSAEVNQNDRRDIQKNHSATHLLHAALKSVLGDHVNQAGSLVEADRLRFDFSHFGPMTNDEIDQVERLVNEEIWKGIDVNIQEMDIASAKEMGAMALFGEKYGDVVRVVNMAPFSIELCGGIHVRNTSEIGLFKIVSESGTGAGVRRIEALTGKAAFLYLEDIQEKFNTMKSQLKVKSDDQVVDKLTQLQDEEKALLKQLEQRDKEITSLKMGNIENQVEEINGYKVLVTEVDVPNAKAIRSTMDDFKSKLQDTIIILASNVDDKVSMVATVPKSLTNNVKAGDLIKQMAPIVGGKGGGRPDMAQGGGTQPENISKSLSFIKDYIKNL
>NC_003923.1|WP_000426912.1|1691780_1692041_-|IreB-family-regulatory-phosphoprotein
MENFDKTMKFDYEELPTQDVRDVLNNVYRTLDERGYNAVNQIVGYLLSGDPAYIPRQNEARNQIRHIDRDVIMEELVSYYLKEQNK
>NC_003923.1|WP_000939059.1|1691348_1691777_-|Holliday-junction-resolvase-RuvX
MLQHKILGLDVGSRTVGIAISDIMGWTAQGLDTLRINEENNELGIDQLVDIIKKHNVGTVVIGLPKNMNNSIGFRGEASLTYKEKLLEAYPSIEIVMWDERLSTMAAERSLLEADVSRQKRKQVIDKMAAVFILQGYLDSLH
>NC_003923.1|WP_000134779.1|1691025_1691334_-|DUF1292-domain-containing-protein
MTEHNHDSQLEINNEEELLTLFDEEGNEVLYRKVLEFYHPEFKKEYVILAEEGAQSDEDDMIELVPMINEPDESGDGGKLVPIETDEEWDMIEEVVNTEMEE
>NC_003923.1|WP_000342266.1|1690102_1690741_-|O-methyltransferase
MDDLNKKYLIDLHQHQNSSIEVLREFAEVNEVPIVDRLTLDLIKQLIRMNNVKNILEIGTAIGYSSMQFASISDDIHVTTIERNETMIQYAKQNLATYHFENQVRIIEGNALEQFENVNDKVYDMIFIDAAKAQSKKFFEIYTPLLKHQGLVITDNVLYHGFVSDIGIVRSRNVRQMVKKVQDYNEWLIKQPGYTTNFLNIDDGLAISIKGE
>NC_003923.1|WP_000137775.1|1689176_1690100_-|U32-family-peptidase
MTELLVTPKSLSHMETLIDLGADAFVIGEQKFGLRLPGEFNRQQMTEAVALAHKNDKKVYAAVNGLFHNYHLDAVEDYINFLHEIRVDRIIFGDPAVVMYVKAQENPIPLHWNAETLVTNHFQCNYWGKRGASRAVLARELNLDEIINIKENSNVEIEVQVQGMTCMFQSKRMLLGNYYTFQDRQMKIERRNDEQSLLLYDEERQNNYPVYEDYNGTHIMSPNDICLIEELAPFFEAGIDSFKIDGILQTEEYINVVTEQYRQAIDLYNEDPEIYEDEKFMLMDPIEEIQPDHRPFDEGFLYKQTVY
>NC_003923.1|WP_000848309.1|1687896_1689165_-|U32-family-peptidase
MKTIEEIKSTPKTVMKKPELLAPAGNLEKLKIAVHYGADAVFLGGQEYGLRSNADNFTMKEIAEGVEFANRYGAKIYVTTNIIAHDENIEGLESYLRNLEKTGATGIIVADPLIIETCKEVAPKLEIHLSTQQSLSNYKAVEYWKEEGLDRVVLARETGAMEMREMKEKVDIEIEAFIHGAMCIAYSGRCTLSNHMTARDSNRGGCCQSCRWDYELLEVDDNGELDVFYNQGEVTPFAMSPKDLKLIESIPQMMDIGVDSLKIEGRMKSIHYIATVVSVYRKVIDAYAADPDNFKINPEWLIELDKCANRDTAPAFFEGTPGYEEQMFGQQQSKKSPFDFCGLVLDYNEDTKIATIQQRNNFKPGQEIEFFGPEIETFTQVVEAIYDEEGNSLDAARHPLQIVQIKVDRPIYPNNMMRKEIG
>NC_003923.1|WP_000648617.1|1687273_1687897_-|uridine-kinase
MKATTIIGIAGGSGSGKTTVTNEIMKNLEGHSVALLAQDYYYKDQKHLTFDERLETNYDHPFAFDNDLLIENLKDLKNGKAVEVPTYDYASHTRSDITIDFKPKDVIIVEGIFALENKVLRDMMDVKIYVDTDADLRILRRLTRDTKERGRSMDSVINQYLSVVRPMHDQFIEPTKKYADIIIPEGGSNKVAIDIMTTKIQSLVSKQ
>NC_003923.1|WP_000066094.1|1698804_1699923_-|tRNA-2-thiouridine(34)-synthase-MnmA
MSNKDIRVVVGMSGGVDSSVTAHVLKEQGYDVIGIFMKNWDDTDENGVCTATEDYNDVIEVCNQIGIPYYAVNFEKEYWDKVFTYFLDEYKKGRTPNPDVMCNKEIKFKAFLDHAMNLGADYVATGHYARIHRHEDGHVEMLRGVDNNKDQTYFLNQLSQQQLSKVMFPIGDIEKIEVRRIAEEQGLVTAKKKDSTGICFIGEKNFKTFLSQYLPAQPGDMITLDGKKMGKHSGLMYYTIGQRHGLGIGGDGDPWFVVGKNLKDNVLYVEQGFHHDALYSDYLIASDYSFVNPEDNDLDQGFECTAKFRYRQKDTKVFVKRENDHALRVTFAEPVRAITPGQAVVFYQGDVCLGGATIDDVFKNEGQLNYVV
>NC_003923.1|WP_000409158.1|1699923_1701066_-|cysteine-desulfurase
MEIYADYAATTPVKPEVVDAMMMIYNSHYGNPSSIHAKGRDARKYLDESRRQIAQLLGADTHEIIFTSGATESNNTAIKGIVKANEQLGNHIITSKIEHHSVLHVFEQLEREGFDVTYLDVDDTGAIDLDQLEETITDKTILVSIMFVNNEVGTVQQIYDIQDIIAETNAYFHVDAVQAIGHLDVKFDEFEIDAMSITAHKFGGPKGVGALLVKDHVTLDYPQLGGEQELKRRAGTENLAQIVGMAKALQLAEKNRDDNNIHLMNLKEQFLVKLQERAIPFELNGSMTDATGHIVNLYFPFVEVETMLTLLDMAQIYVSSGSACTAGSTQPSHVLDAMFEDEERSNHSIRFSFNELTTENEINAIVAEIHKIYFKFKEES
>NC_003923.1|WP_000985895.1|1701377_1702391_+|LLM-class-flavin-dependent-oxidoreductase
MAIKYSALNLVPIREGEDERTAINDMVKLAQHLDELSYERYWIAEHHNAPNLVSSATALLIQHTLEHTKHIRVGSGGIMLPNHAPLIVAEQFGTMATLFPNRVDLGLGRAPGTDMMTASALRRDQHDGVYKFPEEVSLLQQYFGPAHQQAYVRAYPAVGKNVPLYILGSSTDSAHLAARKGLPYVFAGHFAPQQMKEAIEIYKTLFEPSDVLDEPYVIVCLNTIVAENDDEAQYLASSMAQVMVSITRGRMQPVQPPTHELQNILTPREYAMAMERQKISLIGSENTVQQKIQDFMETYGEVNEIMAISYIYDKDMQLDSYRRFKNVINQINEKNTL
>NC_003923.1|WP_000009238.1|1702627_1702774_-|hypothetical-protein
MSFMDKAKDAVEKFKNSDNEQVKNVKDKINEYTGSNNEEKKENEDKEK
>NC_003923.1|WP_000752909.1|1702813_1702996_-|CsbD-family-protein
MADESKFDQFKGNVKETVGNVTDNKELEKEGQQDKATGKAKEVVENAKNKITDAIDKLKK
>NC_003923.1|WP_000704122.1|1703095_1703518_-|Rrf2-family-transcriptional-regulator
MKISTKGRYGLTLMISLAKKEGQGCISLKSIAEENNLSDLYLEQLVGPLRNAGLIRSVRGAKGGYQLRVPAEEISAGDIIRLLEGPITFVESIESEPPAQKQLWIRMRDAVRDVLDNTTLKYLAEYVDTSEDLDGYMFYI
>NC_003923.1|WP_000102740.1|1703602_1704877_+|replication-associated-recombination-protein-A
MSTEPLASRMRPKNIDEIISQQHLVGPRGIIRRMVDTKKLTSMIFYGPPGIGKTSIAKAISGSTQYKFRQLNAVTNTKKDMQLVVEEAKMSGQVILLLDEIHRLDKAKQDFLLPHLENGKIVLIGATTSNPYHAINPAIRSRAQIFELYPLNDEDVRQALTRAIEDEENGLKTYQPKIDEDAMTYFSTQSQGDVRSALNALELAVLSADNDKDGYRHVTLQDAKDCLQKGAFVSDKDGDMHYDVMSAFQKSIRGSDVNAALHYLARLIEAGDLPTIVRRLLVISYEDIGLASPNAGQRTLAAIESAERLGLPEARIPLSQAVIELCLSPKSNSAMSAIDSALSDIRNGHVGQIPNHLKDGHYQGAKDLGRSIGYKYPHQYVNGYVSQQYLPDKLKNKIYYEPKTTSKSEQQLKEIYNNLLKQRP
>NC_003923.1|WP_000682646.1|1705037_1705811_-|tRNA-threonylcarbamoyladenosine-dehydratase
MKHQFSRNELAIGQQGLDLLKQQTVVILGVGGVGSFAAEALARTNIGHIILIDKDDVDITNVNRQLHALTTTVGQSKVSLMEERIKLINPDCKVTPLHMFYTEETYEEIFDNYDIDYFVDASDTIMYKVHLMKECLDRGIKVISSMGAANKTDPTRFTISDISKTHTDPMAKIIRQKLKKLGIRKGIPVVFSDESPIVIREDVKDIVGDKNAINRKGQMPPSSNAFVPSVVGLICASYVVNDVLKDIPVRRIKDKGQ
>NC_003923.1|WP_001790559.1|1705810_1705939_-|hypothetical-protein
MGFIAFNKCFLVEFWENNQSDNAKYKILSYYVLMYKSVKEVK
>NC_003923.1|WP_000044799.1|1706271_1708038_-|aspartate--tRNA-ligase
MSKRTTYCGLVTEAFLGQEITLKGWVNNRRDLGGLIFVDLRDREGIVQVVFNPAFSEEALKIAETVRSEYVVEVQGTVTKRDPETVNPKIKTGQVEVQVTNIKVINKSETPPFSINEENVNVDENIRLKYRYLDLRRQELAQTFKMRHQITRSIRQYLDDEGFFDIETPVLTKSTPEGARDYLVPSRVHDGEFYALPQSPQLFKQLLMISGFDKYYQIVKCFRDEDLRADRQPEFTQVDIEMSFVDQEDVMQMGEEMLKKVVKEVKGVEINGAFPRMTYKEAMRRYGSDKPDTRFEMELIDVSQLGRDMDFKVFKDTVENDGEIKAIVAKGAAEQYTRKDMDALTEFVNIYGAKGLAWVKVVEDGLTGPIGRFFETENVETLLTLTGAEAGDLVMFVADKPNVVAQSLGALRVKLAKELGLIDETKLNFLWVTDWPLLEYDEDAKRYVAAHHPFTSPKEADIAKLGTAPEEAEANAYDIVLNGYELGGGSIRIHDGELQEKMFEVLGFTKEQAQEQFGFLLDAFKYGAPPHGGIALGLDRLVMLLTNRTNLRDTIAFPKTASATCLLTNAPGEVSDKQLEELSLRIRH

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Crispr_ID: NC_003923_7

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_003923_7

1784403-1784489

Orphan

Consensus_repeat	Method
ATGCAAGTTGGGGTGGGGCCCCAACATAGA	CRISPRCasFinder

1 spacers

The CRISPR arrays of NC_003923_7

>merge|NC_003923|7|1784403-1784489|CRISPRCasFinder
ATGCAAGTTGGGGTGGGGCCCCAACATAGAGAATTTCGAAAAGAAATTCTACAGACCATGCAAGTTGGGGTGGGCCCCAACATAGAA

>NC_003923|7|6|1784403-1784489|CRISPRCasFinder
ATGCAAGTTGGGGTGGGGCCCCAACATAGA	GAATTTCGAAAAGAAATTCTACAGACC
ATGCAAGTTGGGGTGGGCCCCAACATAGAA

Protein	Signature genes	Signature genes Name	Protein_function
NC_003923.1\|WP_000634175.1\|1790294_1790795_+\|universal-stress-protein	unknown	unknown	gnl\|CDD\|366180
NC_003923.1\|WP_000818525.1\|1771566_1772928_+\|amino-acid-permease	unknown	unknown	gnl\|CDD\|224038
NC_003923.1\|WP_000471572.1\|1777235_1778093_-\|acetyl-CoA-carboxylase-carboxyltransferase-subunit-beta	unknown	unknown	gnl\|CDD\|235547
NC_003923.1\|WP_000840574.1\|1792330_1793278_-\|class-I-SAM-dependent-methyltransferase	unknown	unknown	gnl\|CDD\|223897
NC_003923.1\|WP_000689998.1\|1789035_1790154_-\|alanine-dehydrogenase	unknown	unknown	gnl\|CDD\|240630
NC_003923.1\|WP_001232648.1\|1773275_1775033_-\|pyruvate-kinase	unknown	unknown	gnl\|CDD\|235784
NC_003923.1\|WP_000160435.1\|1784579_1785878_-\|CBS-domain-containing-protein	unknown	unknown	gnl\|CDD\|226594
NC_003923.1\|WP_000883645.1\|1776291_1777236_-\|acetyl-CoA-carboxylase-carboxyltransferase-subunit-alpha	unknown	unknown	gnl\|CDD\|235580
NC_003923.1\|WP_000040069.1\|1791040_1792243_-\|acetate-kinase	unknown	unknown	gnl\|CDD\|234680
NC_003923.1\|WP_000829167.1\|1770097_1771219_-\|citrate-synthase	unknown	unknown	gnl\|CDD\|184468
NC_003923.1\|WP_000626074.1\|1783184_1784126_-\|pApA-hydrolase-Pde2	unknown	unknown	gnl\|CDD\|223691
NC_003923.1\|WP_000226910.1\|1779966_1783164_-\|DNA-polymerase-III-subunit-alpha	unknown	unknown	gnl\|CDD\|223660
NC_003923.1\|WP_000058389.1\|1778287_1779517_-\|NAD-dependent-malic-enzyme-4	unknown	unknown	gnl\|CDD\|235976
NC_003923.1\|WP_000717561.1\|1775054_1776023_-\|6-phosphofructokinase	unknown	unknown	gnl\|CDD\|235111
NC_003923.1\|WP_000123164.1\|1768780_1770049_-\|NADP-dependent-isocitrate-dehydrogenase	unknown	unknown	gnl\|CDD\|180792
NC_003923.1\|WP_000777188.1\|1786800_1787490_-\|metal-dependent-hydrolase	unknown	unknown	gnl\|CDD\|234811
NC_003923.1\|WP_000136253.1\|1793400_1793895_-\|thiol-peroxidase	unknown	unknown	gnl\|CDD\|179055
NC_003923.1\|WP_001789984.1\|1788813_1788912_-\|hypothetical-protein	unknown	unknown	unknown
NC_003923.1\|WP_000161667.1\|1787664_1788720_+\|aminopeptidase-P-family-protein	unknown	unknown	gnl\|CDD\|223085
NC_003923.1\|WP_000277602.1\|1786082_1786496_+\|universal-stress-protein	unknown	unknown	gnl\|CDD\|366180

Protein	Function_ID	Function_description	E-value
NC_003923.1\|WP_000634175.1\|1790294_1790795_+\|universal-stress-protein	gnl\|CDD\|366180	pfam00582, Usp, Universal stress protein family. The universal stress protein UspA is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. UspA enhances the rate of cell survival during prolonged exposure to such conditions, and may provide a general "stress endurance" activity. The crystal structure of Haemophilus influenzae UspA reveals an alpha/beta fold similar to that of the Methanococcus jannaschii MJ0577 protein, which binds ATP, though UspA lacks ATP-binding activity.	9.27306e-36
NC_003923.1\|WP_000818525.1\|1771566_1772928_+\|amino-acid-permease	gnl\|CDD\|224038	COG1113, AnsP, Gamma-aminobutyrate permease and related permeases [Amino acid transport and metabolism].	0
NC_003923.1\|WP_000471572.1\|1777235_1778093_-\|acetyl-CoA-carboxylase-carboxyltransferase-subunit-beta	gnl\|CDD\|235547	PRK05654, PRK05654, acetyl-CoA carboxylase carboxyltransferase subunit beta.	0
NC_003923.1\|WP_000840574.1\|1792330_1793278_-\|class-I-SAM-dependent-methyltransferase	gnl\|CDD\|223897	COG0827, COG0827, Adenine-specific DNA methylase [DNA replication, recombination, and repair].	2.86206e-56
NC_003923.1\|WP_000689998.1\|1789035_1790154_-\|alanine-dehydrogenase	gnl\|CDD\|240630	cd05305, L-AlaDH, Alanine dehydrogenase NAD-binding and catalytic domains. Alanine dehydrogenase (L-AlaDH) catalyzes the NAD-dependent conversion of pyruvate to L-alanine via reductive amination. Like formate dehydrogenase and related enzymes, L-AlaDH is comprised of 2 domains connected by a long alpha helical stretch, each resembling a Rossmann fold NAD-binding domain. The NAD-binding domain is inserted within the linear sequence of the more divergent catalytic domain. Ligand binding and active site residues are found in the cleft between the subdomains. L-AlaDH is typically hexameric and is critical in carbon and nitrogen metabolism in micro-organisms.	0
NC_003923.1\|WP_001232648.1\|1773275_1775033_-\|pyruvate-kinase	gnl\|CDD\|235784	PRK06354, PRK06354, pyruvate kinase; Provisional.	0
NC_003923.1\|WP_000160435.1\|1784579_1785878_-\|CBS-domain-containing-protein	gnl\|CDD\|226594	COG4109, COG4109, Predicted transcriptional regulator containing CBS domains [Transcription].	0
NC_003923.1\|WP_000883645.1\|1776291_1777236_-\|acetyl-CoA-carboxylase-carboxyltransferase-subunit-alpha	gnl\|CDD\|235580	PRK05724, PRK05724, acetyl-CoA carboxylase carboxyltransferase subunit alpha; Validated.	0
NC_003923.1\|WP_000040069.1\|1791040_1792243_-\|acetate-kinase	gnl\|CDD\|234680	PRK00180, PRK00180, acetate kinase A/propionate kinase 2; Reviewed.	0
NC_003923.1\|WP_000829167.1\|1770097_1771219_-\|citrate-synthase	gnl\|CDD\|184468	PRK14035, PRK14035, citrate synthase; Provisional.	0
NC_003923.1\|WP_000626074.1\|1783184_1784126_-\|pApA-hydrolase-Pde2	gnl\|CDD\|223691	COG0618, COG0618, Exopolyphosphatase-related proteins [General function prediction only].	1.30182e-98
NC_003923.1\|WP_000226910.1\|1779966_1783164_-\|DNA-polymerase-III-subunit-alpha	gnl\|CDD\|223660	COG0587, DnaE, DNA polymerase III, alpha subunit [DNA replication, recombination, and repair].	0
NC_003923.1\|WP_000058389.1\|1778287_1779517_-\|NAD-dependent-malic-enzyme-4	gnl\|CDD\|235976	PRK07232, PRK07232, bifunctional malic enzyme oxidoreductase/phosphotransacetylase; Reviewed.	0
NC_003923.1\|WP_000717561.1\|1775054_1776023_-\|6-phosphofructokinase	gnl\|CDD\|235111	PRK03202, PRK03202, ATP-dependent 6-phosphofructokinase.	0
NC_003923.1\|WP_000123164.1\|1768780_1770049_-\|NADP-dependent-isocitrate-dehydrogenase	gnl\|CDD\|180792	PRK07006, PRK07006, isocitrate dehydrogenase; Reviewed.	0
NC_003923.1\|WP_000777188.1\|1786800_1787490_-\|metal-dependent-hydrolase	gnl\|CDD\|234811	PRK00685, PRK00685, metal-dependent hydrolase; Provisional.	3.09103e-133
NC_003923.1\|WP_000136253.1\|1793400_1793895_-\|thiol-peroxidase	gnl\|CDD\|179055	PRK00522, tpx, thiol peroxidase.	8.69777e-99
NC_003923.1\|WP_000161667.1\|1787664_1788720_+\|aminopeptidase-P-family-protein	gnl\|CDD\|223085	COG0006, PepP, Xaa-Pro aminopeptidase [Amino acid transport and metabolism].	1.48195e-125
NC_003923.1\|WP_000277602.1\|1786082_1786496_+\|universal-stress-protein	gnl\|CDD\|366180	pfam00582, Usp, Universal stress protein family. The universal stress protein UspA is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. UspA enhances the rate of cell survival during prolonged exposure to such conditions, and may provide a general "stress endurance" activity. The crystal structure of Haemophilus influenzae UspA reveals an alpha/beta fold similar to that of the Methanococcus jannaschii MJ0577 protein, which binds ATP, though UspA lacks ATP-binding activity.	6.00154e-19

>NC_003923.1|WP_000626074.1|1783184_1784126_-|pApA-hydrolase-Pde2
MISTLNEIMKCIEDNDTIIIHRHVRPDPDAYGSQLGLKYYIQQKFPQKQVFAVGEAESSLSFIGELDNIDDKTYQDALVIVCDTANAPRIDDERYSTGRKLIKIDHHPAVDQYGDINLVNTNASSTSEIIYDLISHFNDEAIVNKDIASVLYLGIVGDTGRFLFNNTSEHTMEIAGKLIGHDIDHNALLNKMMEKDPKMLPFQGYVLQHFELMDDGFCQVKITEDVLEQFGIQPNEASQFVNTIADIKGLKIWVFAVDEGNEIRCRLRSKGQLIINDIAQDFGGGGHPNASGVSVDSWDEFEQLATALRTKLN
>NC_003923.1|WP_000226910.1|1779966_1783164_-|DNA-polymerase-III-subunit-alpha
MVAYLNIHTAYDLLNSSLKIEDAVRLAVSENVDALAITDTNVLYGFPKFYDACIANNIKPIFGMTIYVTNGLNTVETVVLAKNNDGLKDLYQLSSEIKMNALEHVSFELLKRFSNNMIIIFKKVGDQHRDIVQVFETHNDTYMDHLSISIQGRKHVWIQNVCYQTRQDADTISALAAIRDNTKLDLIHDQEDFGAHFLTEKEINQLDINQEYLTQVDVIAQKCDAELKYHQSLLPQYETPNDESAKKYLWRVLVTQLKKLELNYDVYLERLKYEYKVITNMGFEDYFLIVSDLIHYAKTNDVMVGPGRGSSAGSLVSYLLGITTIDPIKFNLLFERFLNPERVTMPDIDIDFEDTRRERVIQYVQEKYGELHVSGIVTFGHLLARAVARDVGRIMGFDEVTLNEISSLIPHKLGITLDEAYQIDDFKKFVHRNHRHERWFSICKKLEGLPRHTSTHAAGIIINDHPLYEYAPLTKGDTGLLTQWTMTEAERIGLLKIDFLGLRNLSIIHQILTQVKKDLGINIDIEKIPFDDQKVFELLSQGDTTGIFQLESDGVRSVLKKLKPEHFEDIVAVTSLYRPGPMEEIPTYITRRHDPSKVQYLHPHLEPILKNTYGVIIYQEQIMQIASTFANFSYGEADILRRAMSKKNRAVLESERQHFIEGAKQNGYHEDISKQIFDLILKFADYGFPRAHAVSYSKIAYIMSFLKVHYPNYFYANILSNVIGSEKKTAQMIEEAKKQGITILPPNINESHWFYKPSQEGIYLSIGTIKGVGYQSVKVIVDERYQNGKFKDFFDFARRIPKRVKTRKLLEALILVGAFDAFGKTRSTLLQAIDQVLDGDLNIEQDGFLFDILTPKQMYEDKEELPDALISQYEKEYLGFYVSQHPVDKKFVAKQYLTIFKLSNAQNNKPILVQFDKVKQIRTKNGQNMAFVTLNDGIETLDGVIFPNQFKKYEELLSHNDLFIVSGKFDHRKQQRQLIINEIQTLATFEEQKLAFAKQIIIRNKSQIDMFEEMIKATKENANDVVLSFYDETIKQMTTLGYINQKDSMFNNFIQSFNPSDIRLI
>NC_003923.1|WP_000058389.1|1778287_1779517_-|NAD-dependent-malic-enzyme-4
MSLRDEALEMHKRNQGKLEVKPNVKVTNKEELSLAYSPGVAEPCKDIYEDKRKVYDYTIKGNTVAVITDGTAVLGLGNIGPEASIPVMEGKAVLFKSFAGINGVPIALNTTDTEEIIKTVKLLEPNYGGINLEDISAPRCFEIEERLKKETNIPVFHDDQHGTAIVTMAGLVNALRVVNKDIAKIKVVLNGAGAAGIAIVKLLYAYGVRNMVMCDSRGAIFEGRSYGMNPTKDVVAKWTNKDKIEGSLEEVVKDADVFIGVSVANALSQDMVKSMADNPIIFAMANPNPEIIPDDAKAAGARVVGTGRSDYPNQINNVLAFPGIFRGALEVEATHINEEMKKAAVEAIADLIDSSELNEDYCIPGPFDKRVAPSVARNVAKAAMESGVARIEVDPQDVYDKTMKLTDLQ
>NC_003923.1|WP_000471572.1|1777235_1778093_-|acetyl-CoA-carboxylase-carboxyltransferase-subunit-beta
MFKDFFNRTKKKKYLTVQDSKNNDVPAGIMTKCPKCKKIMYTKELAENLNVCFNCDHHIALTAYKRIEAISDEGSFTEFDKGMTSANPLDFPSYLEKIEKDQQKTGLKEAVVTGTAQLDGMKFGVAVMDSRFRMGSMGSVIGEKICRIIDYCTENRLPFILFSASGGARMQEGIISLMQMGKTSVSLKRHSDAGLLYISYLTHPTTGGVSASFASVGDINLSEPKALIGFAGRRVIEQTINEKLPDDFQTAEFLLEHGQLDKVVHRNNMRQTLSEILKIHQEVTK
>NC_003923.1|WP_000883645.1|1776291_1777236_-|acetyl-CoA-carboxylase-carboxyltransferase-subunit-alpha
MLDFEKPLFEIRNKIESLKESQDKNDVDLQEEIDMLEASLERETKKIYTNLKPWDRVQIARLQERPTTLDYIPYIFDSFMELHGDRNFRDDPAMIGGIGFLNGRAVTVIGQQRGKDTKDNIYRNFGMAHPEGYRKALRLMKQAEKFNRPIFTFIDTKGAYPGKAAEERGQSESIATNLIEMASLKVPVIAIVIGEGGSGGALGIGIANKVLMLENSTYSVISPEGAAALLWKDSNLAKIAAETMKITAHDIKQLGIIDDVISEPLGGAHKDIEQQALAIKSAFVAQLDSLESLSRDEIANDRFEKFRNIGSYIE
>NC_003923.1|WP_000717561.1|1775054_1776023_-|6-phosphofructokinase
MKKIAVLTSGGDSPGMNAAVRAVVRTAIYNEIEVYGVYHGYQGLLNDDIHKLELGSVGDTIQRGGTFLYSARCPEFKEQEVRKVAIENLRKRGIEGLVVIGGDGSYRGAQRISEECKEIQTIGIPGTIDNDINGTDFTIGFDTALNTIIGLVDKIRDTASSHARTFIIEAMGRDCGDLALWAGLSVGAETIVVPEVKTDIKEIADKIEQGIKRGKKHSIVLVAEGCMTAQDCQKELSQYINVDNRVSVLGHVQRGGSPTGADRVLASRLGGYAVDLLMQGETAKGVGIKNNKIVATSFDEIFDGKDHKFDYSLYELANKLSI
>NC_003923.1|WP_001232648.1|1773275_1775033_-|pyruvate-kinase
MRKTKIVCTIGPASESEEMIEKLINAGMNVARLNFSHGSHEEHKGRIDTIRKVAKRLDKIVAILLDTKGPEIRTHNMKDGIIELERGNEVIVSMNEVEGTPEKFSVTYENLINDVQVGSYILLDDGLIELQVKDIDHAKKEVKCDILNSGELKNKKGVNLPGVRVSLPGITEKDAEDIRFGIKENVDFIAASFVRRPSDVLEIREILEEQKANISVFPKIENQEGIDNIAEILEVSDGLMVARGDMGVEIPPEKVPMVQKDLIRQCNKLGKPVITATQMLDSMQRNPRATRAEASDVANAIYDGTDAVMLSGETAAGLYPEEAVKTMRNIAVSAEAAQDYKKLLSDRTKLVETSLVNAIGISVAHTALNLNVKAIVAATESGSTARTISKYRPHSDIIAVTPSEETARQCSIVWGVQPVVKKGRKSTDALLNNAVATAVETGRVSNGDLIIITAGVPTGETGTTNMMKIHLVGDEIANGQGIGRGSVVGTTLVAETVKDLEGKDLSDKVIVTNSIDETFVPYVEKALGLITEENGITSPSAIVGLEKGIPTVVGVEKAVKNISNNMLVTIDAAQGKIFEGYANVL
>NC_003923.1|WP_000818525.1|1771566_1772928_+|amino-acid-permease
MAEKLQRELSNRHIQLIAIGGAIGTGLFLGAGQTIALTGPSILLTYIIIGFMLFMFMRGLGEIIIQNTEFKSFADVTNTYIGPFAGFVTGWTYWFCWIITGMAEVTAVAKYVSFWFPEIPNWISALFCVLLLMSFNLLSARLFGELEFWFSIIKIATIIGLIVVGFVMILFAFKTQFGHASFTNLYEHGIFAKGASGFFMSFQMALFSFVGIEMIGVTAGETKDPVKTIPKAINSVPIRILIFYVGALAVIMSIIPWQQVDPDNSPFVKLFALIGIPFAAGLINFVVLTAAASSCNSGIFSNSRMLFGLSSQQQAPPNFSKTNKYGVPHVAIFASSALLLVAALLNYIFPDATKVFTYVTTISTVLFLVVWGLIIIAYINYSRKNPDLHKNATYKLLGGKYMGYLIFVFFIFVFGLLFINVDTRRAIYFIPIWFILLAFMYLRYKRIAAKSNK
>NC_003923.1|WP_000829167.1|1770097_1771219_-|citrate-synthase
MAELQRGLEGVIAAETKISSIIESQLTYAGYDIDDLAENAQFEEVIFLLWNYRLPNEEELAHLKGKLNQYMTLNPRVYTHFEEYVTDHVHPMTALRTSLSYIAHFDPDAENESDENRYERAMRIQAKVASLVTAFARVRQDKEPLKPNPDLSYAANFLYMLRGELPTDIEVEAFNKALILHADHELNASAFTARCAVSSLSDMYSGIVAAVGSLKGPLHGGANEQVMTMLSEIGSIENVDAYLDEKFANKDKVMGFGHRVYKDGDPRAKYLREMSRQITKDAGREELFEMSVKMEKRMAEEKGLIPNVDFYSASVYHCMEIPHDLFTPIFAVSRSAGWIAHILEQYKDNRIMRPRAKYIGETNRKYIPLEERK
>NC_003923.1|WP_000123164.1|1768780_1770049_-|NADP-dependent-isocitrate-dehydrogenase
MTAEKITQGTEGLNVPNEPIIPFIIGDGIGPDIWKAASRVIDAAVEKAYNGEKRIEWKEVLAGQKAFDTTGEWLPQETLDTIKEYLIAVKGPLTTPIGGGIRSLNVALRQELDLFTCLRPVRWFKGVPSPVKRPQDVDMVIFRENTEDIYAGIEFKEGTTEVKKVIDFLQNEMGATNIRFPETSGIGIKPVSKEGTERLVRAAIQYAIDNNRKSVTLVHKGNIMKFTEGSFKQWGYDLALSEFGDQVFTWQQYDEIVEKEGRDAANAAQEKAEKEGKIIIKDSIADIFLQQILTRPAEHDVVATMNLNGDYISDALAAQVGGIGIAPGANINYETGHAIFEATHGTAPKYAGLNKVNPSSVILSSVLMLEHLGWQEAADKITDSIEDTIASKVVTYDFARLMDGAEEVSTSAFADELIKNLK
>NC_003923.1|WP_000160435.1|1784579_1785878_-|CBS-domain-containing-protein
MTKHEQILDYIESLSIGSKISVRKIAKFLNVSEGTAYRAIKDADKMGMVATIDRVGTVRIEKRNRNEIEHLTFNEIVNIIDGQVLGGNKGITKMVSKFAIGAMELKDILKYIGPKTLLIVGNREDVQIEALKRGTAILITGGFKPSNKVINFANEHDLPVLSSSYDTFLVANIINKALFNQKIRKDILIVQDIMTPLDDLSVLFDTMKIADYKRMANRTGHTRFPVVNESYKLVGIVTSREMINTKDDDEIDKVMTRNPIYVNAMSTVASCAHMMIWEGIELIPVVSSNKKTVGVINRQDVLKSMQLLGRQPQMGETINDQIAKYITMNQDGITVEVSPLLINHYGTVSKAAFVSIIEETIQYEMRKFKKGNVMIENLNIVYIKTVPIESHITVRFGILDVGRNFAKIEVNMHSQNDKVASALVICQMFDEV
>NC_003923.1|WP_000277602.1|1786082_1786496_+|universal-stress-protein
MYKNILLGVDTQLKNEKALKEVSKLAGEGTVVTVLNAISEQDAQASIKAGVHLNKLTEERSKRLEKTRKALEDYGIDYDQIIVRGNAKEELLKHANSGKYEIVVLSNRKAEDKKKFVLGSVSHKVAKRATIPVLIVK
>NC_003923.1|WP_000777188.1|1786800_1787490_-|metal-dependent-hydrolase
MKLSFHGQSTIYLEGNNKKVIVDPFISNNPKCDLNIETVQVDYIVLTHGHFDHFGDVVELAKKTGATVIGSAEMADYLSSYHGVENVHGMNIGGKANFDFGSVKFVQAFHSSSFTHENGIPVYLGMPMGIVFEVEGKTIYHTGDTGLFSDMSLIAKRHPVDVCFVPIGDNFTMGIDDASYAINEFIKPKISVPIHYDTFPLIEQDPQQFKDAVNVGDVQILKPGESVQF
>NC_003923.1|WP_000161667.1|1787664_1788720_+|aminopeptidase-P-family-protein
MTKISKIIDELNNQQADAAWITTPLNVYYFTGYRSEPHERLFALLIKKDGKQVLFCPKMEVEEVKASPFTGEIVGYLDTENPFSLYPQTINKLLIESEHLTVARQKQLISGFNVNSFGDVDLTIKQLRNIKSEDEISKIRKAAELADKCIEIGVSYLKEGVTEREVVNHIEQTIKQYGVNEMSFDTMVLFGDHAASPHGTPGDRRLKSNEYVLFDLGVIYEHYCSDMTRTIKFGEPSKEAQEIYNIVLEAETSAIQAIKPGIPLKDIDHIARNIISEKGYGEYFPHRLGHGLGLQEHEYQDVSSTNSNLLEAGMVITIEPGIYVPSVAGVRIEDDILVTNEGYEVLTHYEK
>NC_003923.1|WP_001789984.1|1788813_1788912_-|hypothetical-protein
MNDIDLIHYMLLMNIPAYVFLACLLHIAFRLG
>NC_003923.1|WP_000689998.1|1789035_1790154_-|alanine-dehydrogenase
MKIGIPREIKNNENRVGLSPSGVHALVESGHTVLVETNAGSGSFFEDVDYKEAGAEIVAEQAKVWDVDMVIKVKEPLESEYPYFKEGLVLFTYLHLANEEKLTQALIDRKVISIAYETVQLPDRSLPLLSPMSEVAGRMSAQVGAEFLQKLNGGMGILLGGVPGVPKGKVTIIGGGQAGTNAAKIALGLGADVTILDVNPKRLQQLDDLFGGRVHTIMSNPLNIELYVKQSDLVIGAVLIPGAKAPRLVTEDMIKQMKNGSVIIDIAIDQGGIFETTDKITTHDDPTYIKHGVVHYAVANMPGAVPRTSTLALNNATLPYALMLANKGYREAFKSNQPLSLGLNTYKGHVTNKGVAEAFEMEYKSVEEALQL
>NC_003923.1|WP_000634175.1|1790294_1790795_+|universal-stress-protein
MITYKNILIAVDGSHEAEWAFNRAVGVAKRNDAKLTIVNVIDSRTYSSYEVYDAQFTEKSKHFAEELLNGYKEVATNAGVKDVETRLEFGSPKSIIPKKLAHEINADLIMSGTSGLNAVERFIVGSVSESIVRHAPCDVLVVRTEELPADFQPQVATTQLREKYQN
>NC_003923.1|WP_000040069.1|1791040_1792243_-|acetate-kinase
MSKLILAINAGSSSLKFQLIRMPEEELVTKGLVERIGLKDSIFTIEVNGEKVKTVQDIKDHVEAVDIMLDAFKAHNIINDINDIDGTGHRVVHGGEKFPESVAITDEVEKEIEELSELAPLHNPANLMGIRAFRKLLPNIPHVAIFDTAFHQTMPEKAYLYSLPYHYYKDYGIRKYGFHGTSHKFVSQRAAEMLDKPIEDLRIISCHIGNGASIAAIDGGKSIDTSMGFTPLAGVTMGTRSGNIDPALIPFIMEKTGKTAEQVLEILNKESGLLGLSGTSSDLRDLSEEAESGKARSQMALDVFASKIHKYIGSYAARMHGVDVIVFTAGIGENSVEIRAKVLEGLEFMGVYWDPKKNENLLRGKEGFINYPHSPVKVVVIPTDEESMIARDVMTFGGLK
>NC_003923.1|WP_000840574.1|1792330_1793278_-|class-I-SAM-dependent-methyltransferase
MAEQQTIMERLFHTLDEKAKTLNNENGQSFIENLGLAMEQVYTNERGLLEQSTLQDRRKAFQFAYLSLMQEEKIQANHQITPDSIGLILGFLVERFMNNQEELHIVDIASGAGHLSATVKEVLPEIAVMHHLIEVDPVLSRVSVHLANFLEIPFDVYPQDAIMPLPLEEADIVIGDFPVGYYPIDERSKEFKLGFEEGHSYSHYLLIEQAINALKDAGYAFLVVPSNIFTGEHVKQLEKYIATETEMQAFLNLPPTLFKNEKARKSILILQKKKSGETKPVEVLLANIPDFKIPSQFQGFMTELNQWMDTNRPKK
>NC_003923.1|WP_000136253.1|1793400_1793895_-|thiol-peroxidase
MTEITFKGGPIHLKGQQINEGDFAPDFTVLDNDLNQVTLADYAGKKKLISVVPSIDTGVCDQQTRKFNSDASKEEGIVLTISADLPFAQKRWCASAGLDNVITLSDHRDLSFGENYGVVMEELRLLARAVFVLDADNKVVYKEIVSEGTDFPDFDAALAAYKNI

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Crispr_ID: NC_003923_8

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_003923_8

2226064-2226144

Orphan

Consensus_repeat	Method
CAACTTTAGTTGTTAGGGGCTCTT	CRISPRCasFinder

1 spacers

csa3

The CRISPR arrays of NC_003923_8

>merge|NC_003923|8|2226064-2226144|CRISPRCasFinder
CAACTTTAGTTGTTAGGGGCTCTTATGCATGCGCTTAGCGCAGGCGCTCCTACTTTTCAACTTTAGTTGTTAGGGGCTTCT

>NC_003923|8|7|2226064-2226144|CRISPRCasFinder
CAACTTTAGTTGTTAGGGGCTCTT	ATGCATGCGCTTAGCGCAGGCGCTCCTACTTTT
CAACTTTAGTTGTTAGGGGCTTCT

Protein	Signature genes	Signature genes Name	Protein_function
NC_003923.1\|WP_000908178.1\|2229005_2229788_-\|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|224044
NC_003923.1\|WP_001024095.1\|2222570_2223236_-\|SDR-family-oxidoreductase	unknown	unknown	gnl\|CDD\|187554
NC_003923.1\|WP_001802298.1\|2226479_2226584_-\|hypothetical-protein	unknown	unknown	unknown
NC_003923.1\|WP_000648723.1\|2236656_2237763_+\|mannitol-1-phosphate-5-dehydrogenase	unknown	unknown	gnl\|CDD\|235031
NC_003923.1\|WP_000019743.1\|2223709_2224690_+\|CDF-family-zinc-efflux-transporter-CzrB	unknown	unknown	gnl\|CDD\|224151
NC_003923.1\|WP_000927361.1\|2234078_2236211_+\|BglG-family-transcription-antiterminator	unknown	unknown	gnl\|CDD\|226234
NC_003923.1\|WP_000083807.1\|2232505_2234044_+\|PTS-mannitol-transporter-subunit-IICB	unknown	unknown	gnl\|CDD\|225123
NC_003923.1\|WP_000521495.1\|2245873_2247229_-\|phosphoglucosamine-mutase	unknown	unknown	gnl\|CDD\|237670
NC_003923.1\|WP_000495683.1\|2224955_2226047_+\|hypothetical-protein	unknown	unknown	unknown
NC_003923.1\|WP_000123402.1\|2218890_2220264_-\|EVE-domain-containing-protein	unknown	unknown	gnl\|CDD\|376640
NC_003923.1\|WP_000003759.1\|2223387_2223708_+\|Zn(II)-responsive-metalloregulatory-transcriptional-repressor-CzrA	csa3	COG0640_csa3_CAS-I-A	gnl\|CDD\|238042
NC_003923.1\|WP_000160304.1\|2216545_2217256_+\|purine-nucleoside-phosphorylase	unknown	unknown	gnl\|CDD\|180275
NC_003923.1\|WP_000808817.1\|2220935_2221166_-\|hypothetical-protein	unknown	unknown	unknown
NC_003923.1\|WP_001127960.1\|2221196_2222135_-\|class-I-mannose-6-phosphate-isomerase	unknown	unknown	gnl\|CDD\|224399
NC_003923.1\|WP_001292149.1\|2236222_2236657_+\|PTS-sugar-transporter-subunit-IIA	unknown	unknown	gnl\|CDD\|227014
NC_003923.1\|WP_000070866.1\|2217376_2217820_-\|DNA-starvation/stationary-phase-protection-protein	unknown	unknown	gnl\|CDD\|223854
NC_003923.1\|WP_001792784.1\|2227263_2227422_+\|hypothetical-protein	unknown	unknown	unknown
NC_003923.1\|WP_001123300.1\|2218019_2218433_-\|thiol-disulfide-oxidoreductase-DCC-family-protein	unknown	unknown	gnl\|CDD\|225556
NC_003923.1\|WP_000334465.1\|2230019_2231825_-\|glutamine--fructose-6-phosphate-transaminase-(isomerizing)	unknown	unknown	gnl\|CDD\|234729
NC_003923.1\|WP_000370917.1\|2228080_2228938_-\|Cof-type-HAD-IIB-family-hydrolase	unknown	unknown	gnl\|CDD\|223635

Protein	Function_ID	Function_description	E-value
NC_003923.1\|WP_000908178.1\|2229005_2229788_-\|ABC-transporter-ATP-binding-protein	gnl\|CDD\|224044	COG1119, ModF, ABC-type molybdenum transport system, ATPase component/photorepair protein PhrA [Inorganic ion transport and metabolism].	9.14849e-105
NC_003923.1\|WP_001024095.1\|2222570_2223236_-\|SDR-family-oxidoreductase	gnl\|CDD\|187554	cd05243, SDR_a5, atypical (a) SDRs, subgroup 5. This subgroup contains atypical SDRs, some of which are identified as putative NAD(P)-dependent epimerases, one as a putative NAD-dependent epimerase/dehydratase. Atypical SDRs are distinct from classical SDRs. Members of this subgroup have a glycine-rich NAD(P)-binding motif that is very similar to the extended SDRs, GXXGXXG, and binds NADP. Generally, this subgroup has poor conservation of the active site tetrad; however, individual sequences do contain matches to the YXXXK active site motif, the upstream Ser, and there is a highly conserved Asp in place of the usual active site Asn throughout the subgroup. Atypical SDRs generally lack the catalytic residues characteristic of the SDRs, and their glycine-rich NAD(P)-binding motif is often different from the forms normally seen in classical or extended SDRs. Atypical SDRs include biliverdin IX beta reductase (BVR-B,aka flavin reductase), NMRa (a negative transcriptional regulator of various fungi), progesterone 5-beta-reductase like proteins, phenylcoumaran benzylic ether and pinoresinol-lariciresinol reductases, phenylpropene synthases, eugenol synthase, triphenylmethane reductase, isoflavone reductases, and others. SDRs are a functionally diverse family of oxidoreductases that have a single domain with a structurally conserved Rossmann fold, an NAD(P)(H)-binding region, and a structurally diverse C-terminal region. Sequence identity between different SDR enzymes is typically in the 15-30% range; they catalyze a wide range of activities including the metabolism of steroids, cofactors, carbohydrates, lipids, aromatic compounds, and amino acids, and act in redox sensing. Classical SDRs have an TGXXX[AG]XG cofactor binding motif and a YXXXK active site motif, with the Tyr residue of the active site motif serving as a critical catalytic residue (Tyr-151, human 15-hydroxyprostaglandin dehydrogenase numbering). In addition to the Tyr and Lys, there is often an upstream Ser and/or an Asn, contributing to the active site; while substrate binding is in the C-terminal region, which determines specificity. The standard reaction mechanism is a 4-pro-S hydride transfer and proton relay involving the conserved Tyr and Lys, a water molecule stabilized by Asn, and nicotinamide. In addition to the Rossmann fold core region typical of all SDRs, extended SDRs have a less conserved C-terminal extension of approximately 100 amino acids, and typically have a TGXXGXXG cofactor binding motif. Complex (multidomain) SDRs such as ketoreductase domains of fatty acid synthase have a GGXGXXG NAD(P)-binding motif and an altered active site motif (YXXXN). Fungal type ketoacyl reductases have a TGXXXGX(1-2)G NAD(P)-binding motif.	1.27122e-47
NC_003923.1\|WP_000370917.1\|2228080_2228938_-\|Cof-type-HAD-IIB-family-hydrolase	gnl\|CDD\|223635	COG0561, Cof, Predicted hydrolases of the HAD superfamily [General function prediction only].	7.97122e-60
NC_003923.1\|WP_000648723.1\|2236656_2237763_+\|mannitol-1-phosphate-5-dehydrogenase	gnl\|CDD\|235031	PRK02318, PRK02318, mannitol-1-phosphate 5-dehydrogenase; Provisional.	0
NC_003923.1\|WP_000019743.1\|2223709_2224690_+\|CDF-family-zinc-efflux-transporter-CzrB	gnl\|CDD\|224151	COG1230, CzcD, Co/Zn/Cd efflux system component [Inorganic ion transport and metabolism].	1.20197e-108
NC_003923.1\|WP_000521495.1\|2245873_2247229_-\|phosphoglucosamine-mutase	gnl\|CDD\|237670	PRK14316, glmM, phosphoglucosamine mutase; Provisional.	0
NC_003923.1\|WP_000083807.1\|2232505_2234044_+\|PTS-mannitol-transporter-subunit-IICB	gnl\|CDD\|225123	COG2213, MtlA, Phosphotransferase system, mannitol-specific IIBC component [Carbohydrate transport and metabolism].	0
NC_003923.1\|WP_000123402.1\|2218890_2220264_-\|EVE-domain-containing-protein	gnl\|CDD\|376640	pfam01878, EVE, EVE domain. This domain was formerly known as DUF55. Crystal structures have shown that this domain is part of the PUA superfamily. This domain has been named EVE and is thought to be RNA-binding.	3.86989e-06
NC_003923.1\|WP_000003759.1\|2223387_2223708_+\|Zn(II)-responsive-metalloregulatory-transcriptional-repressor-CzrA	gnl\|CDD\|238042	cd00090, HTH_ARSR, Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to dissociate from DNA in the presence of metal ions.	1.8473e-17
NC_003923.1\|WP_000160304.1\|2216545_2217256_+\|purine-nucleoside-phosphorylase	gnl\|CDD\|180275	PRK05819, deoD, DeoD-type purine-nucleoside phosphorylase.	2.10672e-157
NC_003923.1\|WP_000927361.1\|2234078_2236211_+\|BglG-family-transcription-antiterminator	gnl\|CDD\|226234	COG3711, BglG, Transcriptional antiterminator [Transcription].	1.10767e-67
NC_003923.1\|WP_001127960.1\|2221196_2222135_-\|class-I-mannose-6-phosphate-isomerase	gnl\|CDD\|224399	COG1482, ManA, Phosphomannose isomerase [Carbohydrate transport and metabolism].	7.24075e-129
NC_003923.1\|WP_000070866.1\|2217376_2217820_-\|DNA-starvation/stationary-phase-protection-protein	gnl\|CDD\|223854	COG0783, Dps, DNA-binding ferritin-like protein (oxidative damage protectant) [Inorganic ion transport and metabolism].	1.22744e-67
NC_003923.1\|WP_001123300.1\|2218019_2218433_-\|thiol-disulfide-oxidoreductase-DCC-family-protein	gnl\|CDD\|225556	COG3011, COG3011, Predicted thiol-disulfide oxidoreductase [General function prediction only].	4.46591e-45
NC_003923.1\|WP_000334465.1\|2230019_2231825_-\|glutamine--fructose-6-phosphate-transaminase-(isomerizing)	gnl\|CDD\|234729	PRK00331, PRK00331, isomerizing glutamine--fructose-6-phosphate transaminase.	0
NC_003923.1\|WP_001292149.1\|2236222_2236657_+\|PTS-sugar-transporter-subunit-IIA	gnl\|CDD\|227014	COG4668, MtlA, Mannitol/fructose-specific phosphotransferase system, IIA domain [Carbohydrate transport and metabolism].	2.08822e-62

>NC_003923.1|WP_000495683.1|2224955_2226047_+|hypothetical-protein
MFTYFKSAFKNAKPQLLITLIYALIAFAVIAVVYLLANFQLAKYVQTIAIYSQFGQKPPVDAYLKVIAVLLIAAVVSLFVLVQIFIGITNVMKRAMSHEKVKFTDLFIAFKKGNYLKSVLIGLVSIAMIIVLSLLTSLLYKLFSPVSEMIMNSVQSSYADSTHLIGIAITTQSIIIIVVLLIKAIITWLLLIPVFNFMTSFVESTNDKVKTHLANGFKAMKNGQKTFFKFFIGILLLNLIIILFKTPVGYLISFNTQSLSQSVAENIIRVYTVMTIILFVVIHAIILMGIVQYYLKRGQKITKDKVKTADKNKKVVTEPKNTKVENDKVTTSVETKTEKAQDSLNDNTTKTMTSDKPEDNQPK
>NC_003923.1|WP_000019743.1|2223709_2224690_+|CDF-family-zinc-efflux-transporter-CzrB
MSHSHHHHDHMHSHVTTNNKKVLFISFLIIGLYMFIEIIGGLLANSLALLSDGIHMFSDTFSLGVALVAFIYAEKNATTTKTFGYKRFEVLAALFNGVTLFVISILIVFEAIKRFFVPSEVQSKEMLIISIIGLIVNIVVAFFMFKGGDTSHNLNMRGAFLHVIGDLLGSVGAITAAILIWAFGWTIADPIASILVSVIILKSAWGITKSSINILMEGTPSDVDIDEVITTIKKDSRIQSVHDCHVWTISNDMNALSCHVVVDHTLTMKECELLLENIEHDLLHLNIHHMTIQLETPNHKHDESIICSGTHSHSHNHHAHHHAHAH
>NC_003923.1|WP_000003759.1|2223387_2223708_+|Zn(II)-responsive-metalloregulatory-transcriptional-repressor-CzrA
MSEQYSEINTDTLERVTEIFKALGDYNRIRIMELLSVSEASVGHISHQLNLSQSNVSHQLKLLKSVHLVKAKRQGQSMIYSLDDIHVATMLKQAIHHANHPKESGL
>NC_003923.1|WP_001024095.1|2222570_2223236_-|SDR-family-oxidoreductase
MNILVIGANGGVGSLLVQQLAKENVPFTAGVRQSDQLNALKSQGMKAILVDVENDSIETLTETFKPFDKVIFSVGSGGNTGADKTIIVDLDGAVKSMIASKEANIKHYVMVSTYDSRRQAFDDSGDLKPYTIAKHYADDYLRRSGLNYTILHPGALTNAAGSGKIEAAQYFDGKGEIPREDVATVLKEIVTSNHFNHQEFQIISGEQDIKDALTQFEIEKD
>NC_003923.1|WP_001127960.1|2221196_2222135_-|class-I-mannose-6-phosphate-isomerase
MPLFLQPILKTKLWGGQRLSEFGYQLDNDTTGECWCVSAHPNGTSEIINGPYQGQTLDRIWSEHRELFGDFPSKDFPLLTKIVDARESLSIHVHPDNSYAYEHENGQYGKSECWYIIDAEEDAEIVIGTLAESREEVANHVQHGTIESILRYIKVKPGEFYFIPAGTVHTISSGILAYETMQSSDITYRLYDFNRQDNQYNDRPLNIEKALDVIQYNAPLPNILPESEIIENHKCTHIVSNDFFTLVKWEISGTLNYMKPREFCLVTVLEGEGQMIVDGEIFKLTTGTNFILTSEDLDSVFEGDFTLMISYV
>NC_003923.1|WP_000808817.1|2220935_2221166_-|hypothetical-protein
MKQFLYIALVCGVIAGLGAFLHIPQYPSMTIPRIVAILGIISAMLTFKDKQISASLKFSALLINVLPLCGTFVASN
>NC_003923.1|WP_000123402.1|2218890_2220264_-|EVE-domain-containing-protein
MTAETNYFWLNCGYNRWNHNEPLVGQTALFESGAHFNPSQGFRAFKKAKVGDQVIFYQVQTDTGLLGCGEIISVETGAQNKIRVQFRFNEQLKPLTADYLKRSEALEFRMSNMKETLFNQITAEEFDLISGLGKGEIKIPRYFFLAETEEFEPGNQYTIYTHTYNGIKRNGYHFYTQLEEGDNIIFYNRTKNQSVVGIGEVSKHIHEKPPIPGRTNSTVIEVSYEKDITPITLSTLNKHPKLKNLYFLQENAKQAIASMSQAQYDAIIEMSDNNGLKSPFEMVQKPDMLESEKEEALKPFILLVVDRKEEGLKAANDLLQKANANPVITTGHPDFSEDMLYGKYLPNETGALYYREGFITQLMPKKDKSYLVIDNFNRIDTDIFQTYINVLEGYEVTLPRYNKDGNMIKWSRQKDSFYYFNPNWHIVGITYDSLEEIKEKYSEQFLKYTRIVKVKHD
>NC_003923.1|WP_001123300.1|2218019_2218433_-|thiol-disulfide-oxidoreductase-DCC-family-protein
MPIVYYDGNCIYCYNYVIWLIQHDLPRNYQFATLKGEVGQQFFKQHPEAANKNSVILQKGDCIYFESQAIIKLITALPNRTKLLGVGLWLVPKPVRNFGYRMFANNRNRMWKTTWHQPNDYEKSFFLDDNAKVKLTD
>NC_003923.1|WP_000070866.1|2217376_2217820_-|DNA-starvation/stationary-phase-protection-protein
MSNQQDVVKELNQQVANWTVAYTKLHNFHWYVKGPNFFSLHVKFEELYNEASQYVDELAERILAVGGNPVGTLTECLEQSIVKEAAKGYSAEQMVEELSQDFTNISKQLENAIEIAGNAGDDVSEDMFIGMQTSVDKHNWMFKSYLS
>NC_003923.1|WP_000160304.1|2216545_2217256_+|purine-nucleoside-phosphorylase
MTKGTPHIQPNGVKIAKTVLMPGDPLRAKYIADNFLENVEQFNDVRNMFGYTGTYKGKEVSVMGSGMGIPSIGIYSYELYNFFDVDTIIRIGSCGALQENVNLYDVIIAQAASTNSNYVDQYNIPGHFAPIADFELVTKAKNVADQIGATTHVGNVLSSDTFYNADPTFNDAWKKMGILGIEMESAGLYLNAIHAGKKALGIFTVSDHILRDEATTPEERQNSFTQMMEIALEIAE
>NC_003923.1|WP_001802298.1|2226479_2226584_-|hypothetical-protein
MLLLERTSMSDFEMLMVVLTIIGLVLISTQDHKK
>NC_003923.1|WP_001792784.1|2227263_2227422_+|hypothetical-protein
MSKSSDALFNSLTQSFELIEGVYNELVTDNLKIVMYKPRKESTSGRINRRFK
>NC_003923.1|WP_000370917.1|2228080_2228938_-|Cof-type-HAD-IIB-family-hydrolase
MDNVKAIFLDMDGTILHENNQASPYTKDVINRLREKGYKVFLATGRSHSEIHQLVPQDFAVNGIISSNGTIGEVDGEIIFKHGLSLAQVQQITNLAKRQQIYYEVFPFEGNRVSLKEDETWMRDMIRSQDPINGVSHSEWSSRQDALAGKIDWVTKFPEGEYSKIYLFSSNLEKITAFRDELKQNHVQLQISVSNSSRFNAETMAYQTDKGTGIKEMIAHFGIHQEETLVIGDSDNDRAMFEFGHYTVAMKNARPEIQALTSDVTAYTNEEDGAAKYLAKHFLAD
>NC_003923.1|WP_000908178.1|2229005_2229788_-|ABC-transporter-ATP-binding-protein
MLIQLDQIGRMKQGKTILKKISWQIAKGDKWILYGLNGAGKTTLLNILNAYEPATSGTVNLFGKMPGKVGYSAETVRQHIGFVSHSLLEKFQEGERVIDVVISGAFKSIGVYQDIDEEVRNEAHQLLKLVGMSAKAQQYIGYLSTGEKQRVMIARALMGQPQVLILDEPAAGLDFIARESLLSILDSLSDSYPMLAMIYVTHFIEEITSNFTKILLLKDGESVQQGLIDDILTSENMSRFFQKNVAVQRWNNRFSMAMLE
>NC_003923.1|WP_000334465.1|2230019_2231825_-|glutamine--fructose-6-phosphate-transaminase-(isomerizing)
MCGIVGYIGYDNAKELLLKGLEKLEYRGYDSAGIAVVNDDNTTVFKEKGRIAELRKVADSSDFDGPVGIGHTRWATHGVPNHENSHPHQSSNGRFTLVHNGVIENYEELKGEYLQGVSFISETDTEVIVQLVEYFSNQGLSTEEAFTKVVSLLHGSYALGLLDAEDKDTIYVAKNKSPLLLGVGEGFNVIASDALAMLQVTSEYKEIHDHEIVIVKKDEVIIKDADGNVVERDSYIAEIDASDAEKGVYAHYMLKEIHEQPAVMRRIIQEYQDAEGNLKIDQDIINDVKEADRIYVIAAGTSYHAGLVGKEFLEKWAGVPTEVHVASEFVYNMPLLSEKPLFVYISQSGETADSRAVLVETNKLGHKSLTITNVAGSTLSREADHTLLLHAGPEIAVASTKAYTAQIAVLSILSQIVAKEHGREADIDLLRELAKVTTAIEAIVDDAPIMEQIATDFLETTRNAFFIGRTIDYNVSLEGALKLKEISYIQAEGFAGGELKHGTIALIEEGTPVVGLATQEKVNLSIRGNVKEVVARGAHPCIISMEGLEKEGDTYVIPHVHELLTPLVSVVALQLISYYAALHRDLDVDKPRNLAKSVTVE
>NC_003923.1|WP_000083807.1|2232505_2234044_+|PTS-mannitol-transporter-subunit-IICB
MSQTEEKKGIGRRVQAFGSFLSSMIMPNIGAFIAWGFIAAIFIDNGWLPNKDLATLAGPMITYLIPLLIAFSGGRLIYDLRGGIIAATATMGVIVALPDTPMLLGAMIMGPLVGWLMKKTDQLIQPRTPQGFEMLFNNFSAGILGFIMTIAGFKILAPLMKFIMHILSVAVEALVHAHLLPLVSILVEPAKIVFLNNAINHGVFTPLGADQAAKAGQSILYTIESNPGPGLGILLAYMIFGKGTAKATSYGAGIIHFLGGIHEIYFPYVLMRPLLFIAVILGGMTGVATYQATGFGFKSPASPGSFIVYCLNAPRGEFLHMLLGVFLAALVSFVVAALIMKFTREPKQDLEAATAQMENTKGKKSSVASKLVSSDKNVNTEENASGNVSETSSSDDDPEALLDNYNTEDVDAHNYNNINHVIFACDAGMGSSAMGASMLRNKFKKAGINDITVTNTAINQLPKDAQLVITQKKLTDRAIKQTPNAIHISVDNFLNSPRYEELLNNLKKDDQA
>NC_003923.1|WP_000927361.1|2234078_2236211_+|BglG-family-transcription-antiterminator
MLLSTREKEMIALLIKYHGQYITIHDIAQQLAVSSRTIHRELKGVEAYLTSFSLTLERANKKGLRIAGTDSDLNDLKQSIAQHQTIDLSVEEQKVIIIYALIQAKEPVKQYSLAQEIGVSVQTLAKMLDDLELDLNKYQLSLSRKRGEGIYLVGTESKKREFLSQLMVNNLNSTSVYSVIENHFVFHSLNQIHKDFVDLERIFNVERLLMDYLSALPYQLTESSYLTLTVHIVLSISRIKNGEYVALNDDIYDSVQNTFEHKVASELADKLGQIYDVTFNQAEIAFITIHLRGAKRKNLNDTSLNNRCEENKIKAFVNKVEMISGMTFADLDTLVDGLTLHLNPAINRLQANIETYNPLTDMIKFKYPRLFENVRLALNDCWPDLIFPESEIAFIVLHFGGSIKNQGNRFLNILVVCSSGMGTSRLLSTRLEQVFSEIERITQASVSDLKSLDLSQYDGIISTVNLDIDSPYLTVNPLLPDSDISYVAQFLNTKSTFQETHDKSSNMIDKDDVHVETKDIDGNTSFENEQTSYLTSVFEKHLSDEKSEQLMHHMRSGLTLLDSVKIVSTEVKQWQTYIADYLYQCDAINDPTSFAELLEQRLIDNPGWILSPYPVAIPHLRDNMIKHPMVLITVLEEPLILPSIQNDNQTIKYMISMFIPDNDFMASLVSDLSEFLSLKLESIDTFMENPQELETLLRNKFLERIKKQFI
>NC_003923.1|WP_001292149.1|2236222_2236657_+|PTS-sugar-transporter-subunit-IIA
MSELFSNDNIFLNVNVNSQNEAIEKAGKALVDSGAVTDAYIQAMKDREQVVSTFMGNGLAIPHGTDEAKTNVIHSGLTLLQIPEGVDWDGEVVKVVVGIAGKDGEHLDLLSKIAITFSEEENVDRIVQAKSAEEIKQVFEEADA
>NC_003923.1|WP_000648723.1|2236656_2237763_+|mannitol-1-phosphate-5-dehydrogenase
MKAVHFGAGNIGRGFIGYILADNNVKVTFADVNEEIINALAHDHQYDVILADESKTTTRVNNVDAINSMQPSEALKQAILEADIITTAVGVNILPIIAKSFAPFLKEKTNHVNIVACENAIMATDTLKKAVLDITGPLGNNIHFANSAVDRIVPLQKNENILDVMVEPFYEWVVEKDAWYGPELNHIKYVDDLTPYIERKLLTVNTGHAYLAYAGKFAGKATVLDAVKDSSIEAGLRRVLAETSQYITNEFDFTEAEQAGYVEKIIDRFNNSYLSDEVTRVGRGTLRKIGPKDRIIKPLTYLYNKDLERTGLLNTAALLLKYDDTADQETVEKNNYIKEHGLKAFLSEYAKVDDGLADEIIEAYNSLS
>NC_003923.1|WP_000521495.1|2245873_2247229_-|phosphoglucosamine-mutase
MGKYFGTDGVRGVANQELTPELAFKLGRYGGYVLAHNKGEKHPRVLVGRDTRVSGEMLESALIAGLISIGAEVMRLGIISTPGVAYLTRDMGAELGVMISASHNPVADNGIKFFGSDGFKLSDEQENEIEALLDQENPELPRPVGNDIVHYSDYFEGAQKYLSYLKSTVDVNFEGLKIVLDGANGSTSSLAPFLFGDLEADTETIGCSPDGYNINEKCGSTHPEKLAEKVVETESDFGLAFDGDGDRIIAVDENGQIVDGDQIMFIIGQEMHKNQELNNDMIVSTVMSNLGFYKALEQEGIKSNKTKVGDRYVVEEMRRGNYNLGGEQSGHIVMMDYNTTGDGLLTGIQLASVIKMTGKSLSELAGQMKKYPQSLINVRVTDKYRVEENVDVKEVMTKVEVEMNGEGRILVRPSGTEPLVRVMVEAATDEDAERFAQQIADVVQDKMGLDK

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Crispr_ID: NC_003923_9

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_003923_9

2238386-2238472

Orphan

Consensus_repeat	Method
GCCAACTGATGTTTGCGTATCATTAGT	CRISPRCasFinder

1 spacers

The CRISPR arrays of NC_003923_9

>merge|NC_003923|9|2238386-2238472|CRISPRCasFinder
GCCAACTGATGTTTGCGTATCATTAGTTTGCATATCTTTAGCTTTATTGTTTGCAACTGAGCCAACTGATGTTTGCATATCATTAGT

>NC_003923|9|8|2238386-2238472|CRISPRCasFinder
GCCAACTGATGTTTGCGTATCATTAGT	TTGCATATCTTTAGCTTTATTGTTTGCAACTGA
GCCAACTGATGTTTGCATATCATTAGT

Protein	Signature genes	Signature genes Name	Protein_function
NC_003923.1\|WP_000908178.1\|2229005_2229788_-\|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|224044
NC_003923.1\|WP_000370917.1\|2228080_2228938_-\|Cof-type-HAD-IIB-family-hydrolase	unknown	unknown	gnl\|CDD\|223635
NC_003923.1\|WP_000648723.1\|2236656_2237763_+\|mannitol-1-phosphate-5-dehydrogenase	unknown	unknown	gnl\|CDD\|235031
NC_003923.1\|WP_000521495.1\|2245873_2247229_-\|phosphoglucosamine-mutase	unknown	unknown	gnl\|CDD\|237670
NC_003923.1\|WP_000884735.1\|2262061_2263249_-\|UDPGP-type-1-family-protein	unknown	unknown	gnl\|CDD\|133036
NC_003923.1\|WP_000083807.1\|2232505_2234044_+\|PTS-mannitol-transporter-subunit-IICB	unknown	unknown	gnl\|CDD\|225123
NC_003923.1\|WP_000347896.1\|2248189_2248999_-\|TIGR00159-family-protein	unknown	unknown	gnl\|CDD\|224539
NC_003923.1\|WP_000495683.1\|2224955_2226047_+\|hypothetical-protein	unknown	unknown	unknown
NC_003923.1\|WP_001802298.1\|2226479_2226584_-\|hypothetical-protein	unknown	unknown	unknown
NC_003923.1\|WP_001237503.1\|2259839_2261183_-\|MFS-transporter	unknown	unknown	gnl\|CDD\|129794
NC_003923.1\|WP_000927361.1\|2234078_2236211_+\|BglG-family-transcription-antiterminator	unknown	unknown	gnl\|CDD\|226234
NC_003923.1\|WP_000167873.1\|2249187_2250096_-\|arginase	unknown	unknown	gnl\|CDD\|212515
NC_003923.1\|WP_000047255.1\|2261359_2262043_-\|hemolysin-III-family-protein	unknown	unknown	gnl\|CDD\|224191
NC_003923.1\|WP_001793373.1\|2259267_2259741_-\|multidrug-efflux-transporter-SepA	unknown	unknown	gnl\|CDD\|374975
NC_003923.1\|WP_001792784.1\|2227263_2227422_+\|hypothetical-protein	unknown	unknown	unknown
NC_003923.1\|WP_001141006.1\|2257502_2258945_-\|multidrug-efflux-MFS-transporter-LmrS	unknown	unknown	gnl\|CDD\|129794
NC_003923.1\|WP_000894032.1\|2247255_2248188_-\|YbbR-like-domain-containing-protein	unknown	unknown	gnl\|CDD\|227193
NC_003923.1\|WP_000334465.1\|2230019_2231825_-\|glutamine--fructose-6-phosphate-transaminase-(isomerizing)	unknown	unknown	gnl\|CDD\|234729
NC_003923.1\|WP_000958531.1\|2256290_2257355_-\|P-loop-NTPase	unknown	unknown	gnl\|CDD\|378455
NC_003923.1\|WP_001292149.1\|2236222_2236657_+\|PTS-sugar-transporter-subunit-IIA	unknown	unknown	gnl\|CDD\|227014

Protein	Function_ID	Function_description	E-value
NC_003923.1\|WP_000908178.1\|2229005_2229788_-\|ABC-transporter-ATP-binding-protein	gnl\|CDD\|224044	COG1119, ModF, ABC-type molybdenum transport system, ATPase component/photorepair protein PhrA [Inorganic ion transport and metabolism].	9.14849e-105
NC_003923.1\|WP_000370917.1\|2228080_2228938_-\|Cof-type-HAD-IIB-family-hydrolase	gnl\|CDD\|223635	COG0561, Cof, Predicted hydrolases of the HAD superfamily [General function prediction only].	7.97122e-60
NC_003923.1\|WP_000648723.1\|2236656_2237763_+\|mannitol-1-phosphate-5-dehydrogenase	gnl\|CDD\|235031	PRK02318, PRK02318, mannitol-1-phosphate 5-dehydrogenase; Provisional.	0
NC_003923.1\|WP_000521495.1\|2245873_2247229_-\|phosphoglucosamine-mutase	gnl\|CDD\|237670	PRK14316, glmM, phosphoglucosamine mutase; Provisional.	0
NC_003923.1\|WP_000884735.1\|2262061_2263249_-\|UDPGP-type-1-family-protein	gnl\|CDD\|133036	cd04193, UDPGlcNAc_PPase, UDPGlcNAc pyrophosphorylase catalayzes the synthesis of UDPGlcNAc. UDP-N-acetylglucosamine (UDPGlcNAc) pyrophosphorylase (UAP) (also named GlcNAc1P uridyltransferase), catalyzes the reversible conversion of UTP and GlcNAc1 to PPi and UDPGlcNAc. UDP-N-acetylglucosamine (UDPGlcNAc), the activated form of GlcNAc, is a key precursor of N- and O-linked glycosylations. It is essential for the synthesis of chitin (a major component of the fungal cell wall) and of the glycosylphosphatidylinositol (GPI) linker which anchors a variety of cell surface proteins to the plasma membrane. In bacteria, UDPGlcNAc represents an essential precursor for both peptidoglycan and lipopolysaccharide biosynthesis. Human UAP has two isoforms, resulting from alternative splicing of a single gene and differing by the presence or absence of 17 amino acids. UDPGlcNAc pyrophosphorylase shares significant sequence and structure conservation with UDPglucose pyrophosphorylase.	2.43588e-149
NC_003923.1\|WP_000083807.1\|2232505_2234044_+\|PTS-mannitol-transporter-subunit-IICB	gnl\|CDD\|225123	COG2213, MtlA, Phosphotransferase system, mannitol-specific IIBC component [Carbohydrate transport and metabolism].	0
NC_003923.1\|WP_000347896.1\|2248189_2248999_-\|TIGR00159-family-protein	gnl\|CDD\|224539	COG1624, COG1624, Uncharacterized conserved protein [Function unknown].	2.13611e-103
NC_003923.1\|WP_000958531.1\|2256290_2257355_-\|P-loop-NTPase	gnl\|CDD\|378455	pfam10609, ParA, NUBPL iron-transfer P-loop NTPase. This family contains ATPases involved in plasmid partitioning. It also contains the cytosolic Fe-S cluster assembling factor NBP35 which is required for biogenesis and export of both ribosomal subunits.	6.43129e-115
NC_003923.1\|WP_001237503.1\|2259839_2261183_-\|MFS-transporter	gnl\|CDD\|129794	TIGR00711, Uncharacterized_MFS-type_transporter_YhcA, drug resistance transporter, EmrB/QacA subfamily. This subfamily of drug efflux proteins, a part of the major faciliator family, is predicted to have 14 potential membrane-spanning regions. Members with known activities include EmrB (multiple drug resistance efflux pump) in E. coli, FarB (antibacterial fatty acid resistance) in Neisseria gonorrhoeae, TcmA (tetracenomycin C resistance) in Streptomyces glaucescens, etc. In most cases, the efflux pump is described as having a second component encoded in the same operon, such as EmrA of E. coli. [Cellular processes, Toxin production and resistance, Transport and binding proteins, Other].	2.27036e-43
NC_003923.1\|WP_000927361.1\|2234078_2236211_+\|BglG-family-transcription-antiterminator	gnl\|CDD\|226234	COG3711, BglG, Transcriptional antiterminator [Transcription].	1.10767e-67
NC_003923.1\|WP_000167873.1\|2249187_2250096_-\|arginase	gnl\|CDD\|212515	cd09989, Arginase, Arginase family. This family includes arginase, also known as arginase-like amidino hydrolase family, and related proteins. Arginase is a binuclear Mn-dependent metalloenzyme and catalyzes hydrolysis of L-arginine to L-ornithine and urea (Arg, EC 3.5.3.1), the reaction being the fifth and final step in the urea cycle, providing the path for the disposal of nitrogenous compounds. Arginase controls cellular levels of arginine and ornithine which are involved in protein biosynthesis, and in production of creatine, polyamines, proline and nitric acid. In vertebrates, at least two isozymes have been identified: type I (ARG1) cytoplasmic or hepatic liver-type arginase and type II (ARG2) mitochondrial or non-hepatic arginase. Point mutations in human arginase ARG1 gene lead to hyperargininemia with consequent mental disorders, retarded development and early death. Hyperargininemia is associated with a several-fold increase in the activity of the mitochondrial arginase (ARG2), causing persistent ureagenesis in patients. ARG2 overexpression plays a critical role in the pathophysiology of cholesterol mediated endothelial dysfunction. Thus, arginase is a therapeutic target to treat asthma, erectile dysfunction, atherosclerosis and cancer.	6.64002e-146
NC_003923.1\|WP_000047255.1\|2261359_2262043_-\|hemolysin-III-family-protein	gnl\|CDD\|224191	COG1272, COG1272, Predicted membrane protein, hemolysin III homolog [General function prediction only].	2.41003e-66
NC_003923.1\|WP_001793373.1\|2259267_2259741_-\|multidrug-efflux-transporter-SepA	gnl\|CDD\|374975	pfam17080, SepA, Multidrug Resistance efflux pump. SepA is a drug efflux protein that is involved in bacterial multidrug resistance. It is predicted to have four transmembrane domains.	3.24535e-30
NC_003923.1\|WP_001141006.1\|2257502_2258945_-\|multidrug-efflux-MFS-transporter-LmrS	gnl\|CDD\|129794	TIGR00711, Uncharacterized_MFS-type_transporter_YhcA, drug resistance transporter, EmrB/QacA subfamily. This subfamily of drug efflux proteins, a part of the major faciliator family, is predicted to have 14 potential membrane-spanning regions. Members with known activities include EmrB (multiple drug resistance efflux pump) in E. coli, FarB (antibacterial fatty acid resistance) in Neisseria gonorrhoeae, TcmA (tetracenomycin C resistance) in Streptomyces glaucescens, etc. In most cases, the efflux pump is described as having a second component encoded in the same operon, such as EmrA of E. coli. [Cellular processes, Toxin production and resistance, Transport and binding proteins, Other].	1.08461e-81
NC_003923.1\|WP_000894032.1\|2247255_2248188_-\|YbbR-like-domain-containing-protein	gnl\|CDD\|227193	COG4856, COG4856, Uncharacterized protein conserved in bacteria [Function unknown].	6.26423e-118
NC_003923.1\|WP_000334465.1\|2230019_2231825_-\|glutamine--fructose-6-phosphate-transaminase-(isomerizing)	gnl\|CDD\|234729	PRK00331, PRK00331, isomerizing glutamine--fructose-6-phosphate transaminase.	0
NC_003923.1\|WP_001292149.1\|2236222_2236657_+\|PTS-sugar-transporter-subunit-IIA	gnl\|CDD\|227014	COG4668, MtlA, Mannitol/fructose-specific phosphotransferase system, IIA domain [Carbohydrate transport and metabolism].	2.08822e-62

>NC_003923.1|WP_000648723.1|2236656_2237763_+|mannitol-1-phosphate-5-dehydrogenase
MKAVHFGAGNIGRGFIGYILADNNVKVTFADVNEEIINALAHDHQYDVILADESKTTTRVNNVDAINSMQPSEALKQAILEADIITTAVGVNILPIIAKSFAPFLKEKTNHVNIVACENAIMATDTLKKAVLDITGPLGNNIHFANSAVDRIVPLQKNENILDVMVEPFYEWVVEKDAWYGPELNHIKYVDDLTPYIERKLLTVNTGHAYLAYAGKFAGKATVLDAVKDSSIEAGLRRVLAETSQYITNEFDFTEAEQAGYVEKIIDRFNNSYLSDEVTRVGRGTLRKIGPKDRIIKPLTYLYNKDLERTGLLNTAALLLKYDDTADQETVEKNNYIKEHGLKAFLSEYAKVDDGLADEIIEAYNSLS
>NC_003923.1|WP_001292149.1|2236222_2236657_+|PTS-sugar-transporter-subunit-IIA
MSELFSNDNIFLNVNVNSQNEAIEKAGKALVDSGAVTDAYIQAMKDREQVVSTFMGNGLAIPHGTDEAKTNVIHSGLTLLQIPEGVDWDGEVVKVVVGIAGKDGEHLDLLSKIAITFSEEENVDRIVQAKSAEEIKQVFEEADA
>NC_003923.1|WP_000927361.1|2234078_2236211_+|BglG-family-transcription-antiterminator
MLLSTREKEMIALLIKYHGQYITIHDIAQQLAVSSRTIHRELKGVEAYLTSFSLTLERANKKGLRIAGTDSDLNDLKQSIAQHQTIDLSVEEQKVIIIYALIQAKEPVKQYSLAQEIGVSVQTLAKMLDDLELDLNKYQLSLSRKRGEGIYLVGTESKKREFLSQLMVNNLNSTSVYSVIENHFVFHSLNQIHKDFVDLERIFNVERLLMDYLSALPYQLTESSYLTLTVHIVLSISRIKNGEYVALNDDIYDSVQNTFEHKVASELADKLGQIYDVTFNQAEIAFITIHLRGAKRKNLNDTSLNNRCEENKIKAFVNKVEMISGMTFADLDTLVDGLTLHLNPAINRLQANIETYNPLTDMIKFKYPRLFENVRLALNDCWPDLIFPESEIAFIVLHFGGSIKNQGNRFLNILVVCSSGMGTSRLLSTRLEQVFSEIERITQASVSDLKSLDLSQYDGIISTVNLDIDSPYLTVNPLLPDSDISYVAQFLNTKSTFQETHDKSSNMIDKDDVHVETKDIDGNTSFENEQTSYLTSVFEKHLSDEKSEQLMHHMRSGLTLLDSVKIVSTEVKQWQTYIADYLYQCDAINDPTSFAELLEQRLIDNPGWILSPYPVAIPHLRDNMIKHPMVLITVLEEPLILPSIQNDNQTIKYMISMFIPDNDFMASLVSDLSEFLSLKLESIDTFMENPQELETLLRNKFLERIKKQFI
>NC_003923.1|WP_000083807.1|2232505_2234044_+|PTS-mannitol-transporter-subunit-IICB
MSQTEEKKGIGRRVQAFGSFLSSMIMPNIGAFIAWGFIAAIFIDNGWLPNKDLATLAGPMITYLIPLLIAFSGGRLIYDLRGGIIAATATMGVIVALPDTPMLLGAMIMGPLVGWLMKKTDQLIQPRTPQGFEMLFNNFSAGILGFIMTIAGFKILAPLMKFIMHILSVAVEALVHAHLLPLVSILVEPAKIVFLNNAINHGVFTPLGADQAAKAGQSILYTIESNPGPGLGILLAYMIFGKGTAKATSYGAGIIHFLGGIHEIYFPYVLMRPLLFIAVILGGMTGVATYQATGFGFKSPASPGSFIVYCLNAPRGEFLHMLLGVFLAALVSFVVAALIMKFTREPKQDLEAATAQMENTKGKKSSVASKLVSSDKNVNTEENASGNVSETSSSDDDPEALLDNYNTEDVDAHNYNNINHVIFACDAGMGSSAMGASMLRNKFKKAGINDITVTNTAINQLPKDAQLVITQKKLTDRAIKQTPNAIHISVDNFLNSPRYEELLNNLKKDDQA
>NC_003923.1|WP_000334465.1|2230019_2231825_-|glutamine--fructose-6-phosphate-transaminase-(isomerizing)
MCGIVGYIGYDNAKELLLKGLEKLEYRGYDSAGIAVVNDDNTTVFKEKGRIAELRKVADSSDFDGPVGIGHTRWATHGVPNHENSHPHQSSNGRFTLVHNGVIENYEELKGEYLQGVSFISETDTEVIVQLVEYFSNQGLSTEEAFTKVVSLLHGSYALGLLDAEDKDTIYVAKNKSPLLLGVGEGFNVIASDALAMLQVTSEYKEIHDHEIVIVKKDEVIIKDADGNVVERDSYIAEIDASDAEKGVYAHYMLKEIHEQPAVMRRIIQEYQDAEGNLKIDQDIINDVKEADRIYVIAAGTSYHAGLVGKEFLEKWAGVPTEVHVASEFVYNMPLLSEKPLFVYISQSGETADSRAVLVETNKLGHKSLTITNVAGSTLSREADHTLLLHAGPEIAVASTKAYTAQIAVLSILSQIVAKEHGREADIDLLRELAKVTTAIEAIVDDAPIMEQIATDFLETTRNAFFIGRTIDYNVSLEGALKLKEISYIQAEGFAGGELKHGTIALIEEGTPVVGLATQEKVNLSIRGNVKEVVARGAHPCIISMEGLEKEGDTYVIPHVHELLTPLVSVVALQLISYYAALHRDLDVDKPRNLAKSVTVE
>NC_003923.1|WP_000908178.1|2229005_2229788_-|ABC-transporter-ATP-binding-protein
MLIQLDQIGRMKQGKTILKKISWQIAKGDKWILYGLNGAGKTTLLNILNAYEPATSGTVNLFGKMPGKVGYSAETVRQHIGFVSHSLLEKFQEGERVIDVVISGAFKSIGVYQDIDEEVRNEAHQLLKLVGMSAKAQQYIGYLSTGEKQRVMIARALMGQPQVLILDEPAAGLDFIARESLLSILDSLSDSYPMLAMIYVTHFIEEITSNFTKILLLKDGESVQQGLIDDILTSENMSRFFQKNVAVQRWNNRFSMAMLE
>NC_003923.1|WP_000370917.1|2228080_2228938_-|Cof-type-HAD-IIB-family-hydrolase
MDNVKAIFLDMDGTILHENNQASPYTKDVINRLREKGYKVFLATGRSHSEIHQLVPQDFAVNGIISSNGTIGEVDGEIIFKHGLSLAQVQQITNLAKRQQIYYEVFPFEGNRVSLKEDETWMRDMIRSQDPINGVSHSEWSSRQDALAGKIDWVTKFPEGEYSKIYLFSSNLEKITAFRDELKQNHVQLQISVSNSSRFNAETMAYQTDKGTGIKEMIAHFGIHQEETLVIGDSDNDRAMFEFGHYTVAMKNARPEIQALTSDVTAYTNEEDGAAKYLAKHFLAD
>NC_003923.1|WP_001792784.1|2227263_2227422_+|hypothetical-protein
MSKSSDALFNSLTQSFELIEGVYNELVTDNLKIVMYKPRKESTSGRINRRFK
>NC_003923.1|WP_001802298.1|2226479_2226584_-|hypothetical-protein
MLLLERTSMSDFEMLMVVLTIIGLVLISTQDHKK
>NC_003923.1|WP_000495683.1|2224955_2226047_+|hypothetical-protein
MFTYFKSAFKNAKPQLLITLIYALIAFAVIAVVYLLANFQLAKYVQTIAIYSQFGQKPPVDAYLKVIAVLLIAAVVSLFVLVQIFIGITNVMKRAMSHEKVKFTDLFIAFKKGNYLKSVLIGLVSIAMIIVLSLLTSLLYKLFSPVSEMIMNSVQSSYADSTHLIGIAITTQSIIIIVVLLIKAIITWLLLIPVFNFMTSFVESTNDKVKTHLANGFKAMKNGQKTFFKFFIGILLLNLIIILFKTPVGYLISFNTQSLSQSVAENIIRVYTVMTIILFVVIHAIILMGIVQYYLKRGQKITKDKVKTADKNKKVVTEPKNTKVENDKVTTSVETKTEKAQDSLNDNTTKTMTSDKPEDNQPK
>NC_003923.1|WP_000521495.1|2245873_2247229_-|phosphoglucosamine-mutase
MGKYFGTDGVRGVANQELTPELAFKLGRYGGYVLAHNKGEKHPRVLVGRDTRVSGEMLESALIAGLISIGAEVMRLGIISTPGVAYLTRDMGAELGVMISASHNPVADNGIKFFGSDGFKLSDEQENEIEALLDQENPELPRPVGNDIVHYSDYFEGAQKYLSYLKSTVDVNFEGLKIVLDGANGSTSSLAPFLFGDLEADTETIGCSPDGYNINEKCGSTHPEKLAEKVVETESDFGLAFDGDGDRIIAVDENGQIVDGDQIMFIIGQEMHKNQELNNDMIVSTVMSNLGFYKALEQEGIKSNKTKVGDRYVVEEMRRGNYNLGGEQSGHIVMMDYNTTGDGLLTGIQLASVIKMTGKSLSELAGQMKKYPQSLINVRVTDKYRVEENVDVKEVMTKVEVEMNGEGRILVRPSGTEPLVRVMVEAATDEDAERFAQQIADVVQDKMGLDK
>NC_003923.1|WP_000894032.1|2247255_2248188_-|YbbR-like-domain-containing-protein
MLESKWGLRFIAFLLALFFFLSVNNVFGNIFNTGNLGQKSSKTIQDVPVEILYNTKDLHLTKAPETVNVTISGPQSKIIKIENPEDLRVVIDLSNAKAGKYQEKYQVKGLADDIHYSVKPKLANITLENKVTKKMTVQPDVSQSDIDPLYKITKQEVSPQTVKVTGGEEQLNDIAYLKATFKTNKKINGDTKDVAEVTAFDKKLNKLNVSIQPNEVNLQVKVEPFSKKVKVNVKQKGSLADDKELSSIDLEDKEIEIFGSRDDLQNISEVDAEVDLDGISESTEKTVKINLPEHVTKAQPSETKAYINVK
>NC_003923.1|WP_000347896.1|2248189_2248999_-|TIGR00159-family-protein
MDFSNFFQNLSTLKIVTSILDLLIVWYVLYLLITVFKGTKAIQLLKGILVIVIGQQISMILNLTATSKLFDIVIQWGVLALIVIFQPEIRRALEQLGRGSFLKRYTSNTYSKDEEKLIQSVSKAVQYMAKRRIGALIVFEKETGLQDYIETGIAMDSNISQELLINVFIPNTPLHDGAMIIQGTKIAAAASYLPLSDSPKISKSLGTRHRAAVGISEVSDAFTVIVSEETGDISVTFDGKLRRDISNEIFEELLAEHWFGTRFQKKGVK
>NC_003923.1|WP_000167873.1|2249187_2250096_-|arginase
MTKTKAIDIIGAPSTFGQRKLGVDLGPTAIRYAGLISRLKQLDLDVYDKGDIKVPVVNIEKFHSEQKGLRNYDEIIDVNQKLNKEVSASIENNRFPLVLGGDHSIAVGSVSAISKHYNNLGVIWYDAHGDLNIPEESPSGNIHGMPLRILTGEGPKELLELNSNVIKPENIVLIGMRDLDKGERQFIKDHNIKTFTMSDIDKLGIKEVIENTIEYLKSRNVDGVHLSLDVDALDPLETPGTGTRVLGGLSYRESHFALELLHQSHLISSMDLVEVNPLIDSNNHTAEQAVSLVGTFFGETLL
>NC_003923.1|WP_000958531.1|2256290_2257355_-|P-loop-NTPase
MLTVDQVKELVGEIKDPIIDVPLKETEGIVEVSIKEEKEHVSVKLAMAQLGGAPQLDLQMAVVNALKENGAKTVGIRFETLPEEKVNQFKPKEENKPKTIEGLLSQNNPVEFIAIASGKGGVGKSTVAVNLAVALAREGKKVGLVDADIYGFSVPDMMGIDEKPGIKGKEVIPVERHGVKVISMAFFVEENAPVIWRGPMLGKMLTNFFTEVKWGDIEYLILDLPPGTGDVALDVHTMLPSSKEIIVTTPHPTAAFVAARAGAMAKHTDHSILGVIENMSYFESKETGNKEYVFGKGGGTKLADELNTQLLGELPLEQPSWNPKDFAPSIYQSDDRLGKIYSSIAQKVIAATNK
>NC_003923.1|WP_001141006.1|2257502_2258945_-|multidrug-efflux-MFS-transporter-LmrS
MAKVELTTRRRNFIVAVMLISAFVAILNQTLLNTALPSIMRELNINESTSQWLVTGFMLVNGVMIPLTAYLMDRIKTRPLYLAAMGTFLLGSIVAALAPNFGVLMLARVIQAMGAGVLMPLMQFTLFTLFSKEHRGFAMGLAGLVIQFAPAIGPTVTGLIIDQASWRVPFIIIVGIALVAFVFGLVSISSYNEVKYTKLDKRSVMYSTIGFGLMLYAFSSAGDLGFTSPIVIGALIISMVIIYLFIRRQFNITNALLNLRVFKNRTFALCTISSMIIMMSMVGPALLIPLYVQNSLSLSALLSGLVIMPGAIINGIMSVFTGKFYDKYGPRPLIYTGFTILTITTIMLCFLHTDTSYTYLIVVYAIRMFSVSLLMMPINTTGINSLRNEEISHGTAIMNFGRVMAGSLGTALMVTLMSFGAKIFLSTSPSHLTATEIKQQSIAIGVDISFAFVAVLVMAAYVIALFIREPKEIESNRRKF
>NC_003923.1|WP_001793373.1|2259267_2259741_-|multidrug-efflux-transporter-SepA
MIVNYLKHKFYNLLTTMVVLFIFVLSGAIFLTFLGFGLYGLSRILIYFRLGDFTYNRSMYDNLLYYGSYIIFGYFIIFAVEHLMDYFRKMLPENAYFRGATFHLISYTVATTLFYFIIHLNYVYINIDFWVIMVIIGFLYVCKLQFYPESKNLNNRK
>NC_003923.1|WP_001237503.1|2259839_2261183_-|MFS-transporter
MRLKSIITVIALILIMFMSAIESSIISLALPTIKQDLNAGNLISLIFTAYFIALVIANPIVGELLSRFKIIYVAIAGLLLFSIGSFMCGLSTNFTMLIISRVIQGFGSGVLMSLSQIVPKLAFEIPLRYKIMGIVGSVWGISSIIGPLLGGGILEFATWHWLFYINIPIAIIAIILVIWTFHFPEEETVAKSKFDTKGLTLFYVFIGLIMFALLNQQLLLLNFLSFILAIVVAMCLFKVEKHVSSPFLPVVEFNRSITLVFITDLLTAICLMGFNLYIPVYLQEQLGLSPLQSGLVIFPLSLAWITLNFNLHRIEAKLSRKVIYLLSFTLLLVSSIIISFGIKLPVLIAFVLILAGLSFGYIYTKDSVIVQEETSPLQMKKMMSFYGLTKNLGASIGSTIMGYLYAIQSGIFGPNLHNVLSAVAVISIGLIVLWVVFFKEQSSQSKE
>NC_003923.1|WP_000047255.1|2261359_2262043_-|hemolysin-III-family-protein
MSKSTKKSNDTIVETFKDIIPLSFGEEIGNAASHGVAALLTLLVLPYAAVHSYIAHGTLASVSMSIYVISIFMMFISSTIYHSMQNETPHKYILRIIDHSMIYVAISGTYTPILLTVVGGWIGWTVFILLWGTTLWGILYKSIAVKVNQKLSLIVYLVMGWVGIILLPIIFIRTSWIFILFIFLGGVSYTIGAWFYAQKNRPYFHMIWHIFIVIASLLHLIAILYFM
>NC_003923.1|WP_000884735.1|2262061_2263249_-|UDPGP-type-1-family-protein
MLDKNQLAKYKQDHLCEYEKIMSNNEKEALEEKVASLDLDFIAKLYNDLYINKKTIDDVSAVSEVKYDIKSQMSDDEIKRLEEQGLQAIKEGQFAVLLMAGGQGTRLGYKGPKGSFEIEGVSLFELQANQLKTLNHQSGHTIQWYIMTSDINHEETLAYFEAHSYFGYDQEAIHFFKQDNIVALSEEGKLILNQQGRIMETPNGNGGVFKSLDKAGYLEEMSNNGVKYIFLNNIDNVLVKVLDPLFAGFTVEHDYDITSKTIQPKPGESVGRLVNVDCKDTVLEYSELDPEVANQFNNANIGIHAFKLGFILNAVNRELPYHLAIKNLKQLDENFGVIEQPTLKFELFYFDIFTYGTSFVTLQVPREEEFSPLKNKEGKDSVATATEDLRRMGLI

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Crispr_ID: NC_003923_10

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_003923_10

2337571-2337656

Orphan

Consensus_repeat	Method
CCAACTTGCACATTATTGTAAGCTGACTTT	CRISPRCasFinder

1 spacers

The CRISPR arrays of NC_003923_10

>merge|NC_003923|10|2337571-2337656|CRISPRCasFinder
CCAACTTGCACATTATTGTAAGCTGACTTTTCGTCACCTTCTATGTTGGGGCCCCGCCAACTTGCACATTATTGTAAGCTGACTTT

>NC_003923|10|9|2337571-2337656|CRISPRCasFinder
CCAACTTGCACATTATTGTAAGCTGACTTT	TCGTCACCTTCTATGTTGGGGCCCCG
CCAACTTGCACATTATTGTAAGCTGACTTT

Protein	Signature genes	Signature genes Name	Protein_function
NC_003923.1\|WP_001790034.1\|2337381_2337552_+\|hypothetical-protein	unknown	unknown	unknown
NC_003923.1\|WP_000051210.1\|2328142_2328307_+\|hypothetical-protein	unknown	unknown	unknown
NC_003923.1\|WP_000230173.1\|2337833_2338856_-\|GTP-3',8-cyclase-MoaA	unknown	unknown	gnl\|CDD\|274250
NC_003923.1\|WP_000134536.1\|2341984_2342479_+\|cyclic-pyranopterin-monophosphate-synthase-MoaC	unknown	unknown	gnl\|CDD\|236483
NC_003923.1\|WP_001161085.1\|2328551_2328869_+\|hypothetical-protein	unknown	unknown	unknown
NC_003923.1\|WP_000184413.1\|2335592_2336804_+\|MFS-transporter	unknown	unknown	gnl\|CDD\|341042
NC_003923.1\|WP_000592298.1\|2329052_2332220_-\|efflux-RND-transporter-permease-subunit	unknown	unknown	gnl\|CDD\|223911
NC_003923.1\|WP_000808500.1\|2339720_2340167_-\|molybdenum-cofactor-biosynthesis-protein-MoaE	unknown	unknown	gnl\|CDD\|223391
NC_003923.1\|WP_000866971.1\|2339481_2339715_-\|molybdopterin-converting-factor-subunit-1	unknown	unknown	gnl\|CDD\|340452
NC_003923.1\|WP_000913019.1\|2344191_2344797_-\|ATP-binding-cassette-domain-containing-protein	unknown	unknown	gnl\|CDD\|226628
NC_003923.1\|WP_000643988.1\|2338875_2339475_-\|molybdenum-cofactor-guanylyltransferase-MobA	unknown	unknown	gnl\|CDD\|234725
NC_003923.1\|WP_001566779.1\|2333990_2334242_+\|hypothetical-protein	unknown	unknown	unknown
NC_003923.1\|WP_000259724.1\|2340662_2341922_-\|molybdopterin-molybdotransferase-MoeA	unknown	unknown	gnl\|CDD\|238452
NC_003923.1\|WP_000602937.1\|2340180_2340666_-\|molybdopterin-guanine-dinucleotide-biosynthesis-protein-B	unknown	unknown	gnl\|CDD\|224677
NC_003923.1\|WP_000600973.1\|2334233_2334998_-\|VOC-family-protein	unknown	unknown	gnl\|CDD\|379203
NC_003923.1\|WP_000066900.1\|2336905_2337256_-\|HTH-type-transcriptional-regulator-SarV	unknown	unknown	gnl\|CDD\|130944
NC_003923.1\|WP_000413863.1\|2332336_2333602_-\|lipid-II:glycine-glycyltransferase-FemX	unknown	unknown	gnl\|CDD\|225224
NC_003923.1\|WP_000076923.1\|2343017_2344022_-\|ThiF-family-adenylyltransferase	unknown	unknown	gnl\|CDD\|181084
NC_003923.1\|WP_000503820.1\|2342480_2342987_-\|molybdenum-cofactor-biosynthesis-protein-MoaB	unknown	unknown	gnl\|CDD\|223595
NC_003923.1\|WP_000951060.1\|2335159_2335600_+\|winged-helix-DNA-binding-protein	unknown	unknown	gnl\|CDD\|197670

Protein	Function_ID	Function_description	E-value
NC_003923.1\|WP_000866971.1\|2339481_2339715_-\|molybdopterin-converting-factor-subunit-1	gnl\|CDD\|340452	cd00754, Ubl_MoaD, ubiquitin-like (Ubl) domain found in molybdenum cofactor biosynthesis protein D (MoaD) and similar proteins. MoaD, also termed molybdopterin synthase sulfur carrier subunit, or MPT synthase subunit 1, or MPT synthase small subunit, or molybdopterin-converting factor small subunit, or molybdopterin-converting factor subunit 1, is a conserved small sulfur carrier protein that has beta-grasp ubiquitin-like (Ubl) fold involved in biosynthesis of the molybdenum cofactor (Moco), an essential cofactor of a diverse group of redox enzymes. MoaD is activated in an ATP-dependent manner by sulfurtransferases similar to the activation mechanism of ubiquitin-activating enzyme E1.	8.16473e-25
NC_003923.1\|WP_000230173.1\|2337833_2338856_-\|GTP-3',8-cyclase-MoaA	gnl\|CDD\|274250	TIGR02666, Cyclic_pyranopterin_monophosphate_synthase, molybdenum cofactor biosynthesis protein A, bacterial. The model for this family describes molybdenum cofactor biosynthesis protein A, or MoaA, as found in bacteria. It does not include the family of probable functional equivalent proteins from the archaea. MoaA works together with MoaC to synthesize precursor Z from guanine. [Biosynthesis of cofactors, prosthetic groups, and carriers, Molybdopterin].	1.0538e-165
NC_003923.1\|WP_000134536.1\|2341984_2342479_+\|cyclic-pyranopterin-monophosphate-synthase-MoaC	gnl\|CDD\|236483	PRK09364, moaC, cyclic pyranopterin monophosphate synthase MoaC.	9.25584e-98
NC_003923.1\|WP_000643988.1\|2338875_2339475_-\|molybdenum-cofactor-guanylyltransferase-MobA	gnl\|CDD\|234725	PRK00317, mobA, molybdopterin-guanine dinucleotide biosynthesis protein MobA; Reviewed.	5.68918e-67
NC_003923.1\|WP_000592298.1\|2329052_2332220_-\|efflux-RND-transporter-permease-subunit	gnl\|CDD\|223911	COG0841, AcrB, Cation/multidrug efflux pump [Defense mechanisms].	0
NC_003923.1\|WP_000808500.1\|2339720_2340167_-\|molybdenum-cofactor-biosynthesis-protein-MoaE	gnl\|CDD\|223391	COG0314, MoaE, Molybdopterin converting factor, large subunit [Coenzyme metabolism].	5.56799e-58
NC_003923.1\|WP_000913019.1\|2344191_2344797_-\|ATP-binding-cassette-domain-containing-protein	gnl\|CDD\|226628	COG4148, ModC, ABC-type molybdate transport system, ATPase component [Inorganic ion transport and metabolism].	3.32197e-115
NC_003923.1\|WP_000184413.1\|2335592_2336804_+\|MFS-transporter	gnl\|CDD\|341042	cd17489, MFS_YfcJ_like, Escherichia coli YfcJ, YhhS, and similar transporters of the Major Facilitator Superfamily. This subfamily is composed of Escherichia coli membrane proteins, YfcJ and YhhS, Bacillus subtilis uncharacterized MFS-type transporter YwoG, and similar proteins. YfcJ and YhhS are putative arabinose efflux transporters. YhhS has been implicated glyphosate resistance. YfcJ-like arabinose efflux transporters belong to the bacterial MdtG-like and eukaryotic solute carrier 18 (SLC18) family of the Major Facilitator Superfamily (MFS) of transporters. MFS proteins are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	1.54033e-72
NC_003923.1\|WP_000259724.1\|2340662_2341922_-\|molybdopterin-molybdotransferase-MoeA	gnl\|CDD\|238452	cd00887, MoeA, MoeA family. Members of this family are involved in biosynthesis of the molybdenum cofactor (MoCF), an essential cofactor of a diverse group of redox enzymes. MoCF biosynthesis is an evolutionarily conserved pathway present in eubacteria, archaea and eukaryotes. MoCF contains a tricyclic pyranopterin, termed molybdopterin (MPT). MoeA, together with MoaB, is responsible for the metal incorporation into MPT, the third step in MoCF biosynthesis. The plant homolog Cnx1 is a MoeA-MogA fusion protein. The mammalian homolog gephyrin is a MogA-MoeA fusion protein, that plays a critical role in postsynaptic anchoring of inhibitory glycine receptors and major GABAa receptor subtypes.	6.35078e-159
NC_003923.1\|WP_000951060.1\|2335159_2335600_+\|winged-helix-DNA-binding-protein	gnl\|CDD\|197670	smart00347, HTH_MARR, helix_turn_helix multiple antibiotic resistance protein.	2.28933e-15
NC_003923.1\|WP_000600973.1\|2334233_2334998_-\|VOC-family-protein	gnl\|CDD\|379203	pfam13468, Glyoxalase_3, Glyoxalase-like domain. This domain is related to the Glyoxalase domain pfam00903.	4.64519e-37
NC_003923.1\|WP_000066900.1\|2336905_2337256_-\|HTH-type-transcriptional-regulator-SarV	gnl\|CDD\|130944	TIGR01889, Pleiotropic_Regulator_Of_Virulence, staphylococcal accessory regulator family. This model represents a family of transcriptional regulatory proteins in Staphylococcus aureus and Staphylococcus epidermidis. Some members contain two tandem copies of this region. This family is related to the MarR transcriptional regulator family described by pfam01047. [Regulatory functions, DNA interactions].	2.64009e-20
NC_003923.1\|WP_000413863.1\|2332336_2333602_-\|lipid-II:glycine-glycyltransferase-FemX	gnl\|CDD\|225224	COG2348, COG2348, Peptidoglycan interpeptide bridge formation enzyme [Cell wall/membrane/envelope biogenesis].	3.69463e-143
NC_003923.1\|WP_000076923.1\|2343017_2344022_-\|ThiF-family-adenylyltransferase	gnl\|CDD\|181084	PRK07688, PRK07688, thiamine/molybdopterin biosynthesis ThiF/MoeB-like protein; Validated.	3.23825e-132
NC_003923.1\|WP_000503820.1\|2342480_2342987_-\|molybdenum-cofactor-biosynthesis-protein-MoaB	gnl\|CDD\|223595	COG0521, MoaB, Molybdopterin biosynthesis enzymes [Coenzyme metabolism].	9.7838e-65
NC_003923.1\|WP_000602937.1\|2340180_2340666_-\|molybdopterin-guanine-dinucleotide-biosynthesis-protein-B	gnl\|CDD\|224677	COG1763, MobB, Molybdopterin-guanine dinucleotide biosynthesis protein [Coenzyme metabolism].	4.35501e-50

>NC_003923.1|WP_001790034.1|2337381_2337552_+|hypothetical-protein
MFRFISFGQLVVYSTTFIPKKDILQLNGMECDINVKEPLKIYYVVILKSGIEMIFS
>NC_003923.1|WP_000066900.1|2336905_2337256_-|HTH-type-transcriptional-regulator-SarV
MSNKVQRFIEAERELSQLKHWLKTTHKISIEEFVVLFKVYEAEKISGKELRDTLHFEMLWDTSKIDVIIRKIYKKELISKLRSETDERQVFYFYSTSQKKLLDKITKEIEVLSVTN
>NC_003923.1|WP_000184413.1|2335592_2336804_+|MFS-transporter
MTNQGSLNKSPIFTKSFTINFFVNFIVYLCMYLLLVVIAGYSKQAFDASDSLAGLVVGLFIVGSLIGRFATGKFVNQIGPKRLLFIGLIALIITQLLYFIDGSLAFLIFVRLINGIATAVVTTATGTIAAYVTPVNRKSEGISLFSLSLVLGTAIGPFLGMLLITKYPIDLLFIICVILGILGLIISLFIKVDFEVTNNKTETNVIDKPRFSIHQFIAKEAIPVAVIMLLIGVTYASILTYLQAFALERHLVTAASYFFICYAIASLITRPIAGRLMDDKNENIIVYPAFIMLFLSFVCLISSYQSWLILLAGACLGLGYGNLSSAMQSIAIKVSPPIKYGIATSTFYVGLDAGVGFGPSFLGLFTHMFSYSEIFGFMAALAIITMLVYFLIHGRHVTRNAMN
>NC_003923.1|WP_000951060.1|2335159_2335600_+|winged-helix-DNA-binding-protein
MLSQEFFNSFITIYRPYLKLAEPILEKHNIYYGQWLILRDIAKHQPTTLIEISHRRAIEKPTARKTLKALIENDLITVENSLEDKRQKFLTLTPKGHELYEIVCLDVQKLQQAVVAKTNISQDQMQETINVMNQIHKILLKETHND
>NC_003923.1|WP_000600973.1|2334233_2334998_-|VOC-family-protein
MILKFDHIIHYIDQLDRFSFPGDVIKLHSGGYHHKYGTFNKLGYINENYIELLDVENNEKLKKMAKTIEGGVAFATQIVQEKYEQGFKNICLRTNNIEAVKNKLQSERVEVVGPIQMERDTHKDGKVKWQLLYIMNQDDDEIKPPFFIQWEESDSMRTKKLQKYFQKQFSIETVIVKSKNRSQTVSNWLKWFDMDIVEENDHYTDLILKNDDIYFRIEDGKVSKYHSVIIKDAQATSPYSIFIRGAIYRFEPLV
>NC_003923.1|WP_001566779.1|2333990_2334242_+|hypothetical-protein
MRTIILSLFIIMNIVAIIMTLSQPLTVNYFSLRVILIFFTFILSIFFILIKSSRLNNILTILSIVLAIIHMGILAHSTYVYLY
>NC_003923.1|WP_000413863.1|2332336_2333602_-|lipid-II:glycine-glycyltransferase-FemX
MEKMHITNQEHDAFVKSHPNGDLLQLTKWAETKKLTGWYARRIAVGRDGEVQGVAQLLFKKVPKLPYTLCYISRGFVVDYSNKEALNALLDSAKEIAKAEKAYAIKIDPDVEVDKGTDALQNLKALGFKHKGFKEGLSKDYIQPRMTMITPIDKNDDELLNSFERRNRSKVRLALKRGTTVERSDREGLKTFAELMKITGERDGFLTRDISYFENIYDALHEDGDAELFLVKLDPKENIAKVNQELNELHAEIAKWQQKMETSEKQAKKAQNMINDAQNKIAKNEDLKRDLEALEKEHPEGIYLSGALLMFAGSKSYYLYGASSNEFRDFLPNHHMQYTMMKYAREHGATTYDFGGTDNDPDKDSEHYGLWAFKKVWGTYLSEKIGEFDYVLNQPLYQLIEQVKPRLTKAKIKISRKLKRK
>NC_003923.1|WP_000592298.1|2329052_2332220_-|efflux-RND-transporter-permease-subunit
MIKKLLQFSLGNKFAIFLMVVLVVLGGVYASAKLKLELLPNVQNPVISVTTTMPGATPQSTQDEISSKIDNQVRSLAYVKNVKTQSIQNASIVTVEYENNTDMDKAEEQLKKEIDKIKFKDEVGQPELRRNSMDAFPVLAYSFSNKENDLKKVTKVLNEQLIPKLQTVDGVQNAQLNGQTNREITLKFKQNELEKYGLTADDVENYLKTATRTTPLGLFQFGDKDKSIVVDGQYQSVDAFKNINIPLTFAGGQGQSQSQSDNKQNSAMSDVNQASPQQNSKASAPNNISGMPTAKLGDLADITVGDVRTSISKTNGKDAVNLQITKAQDANTVQVAKDVQRKIDTFVDENKDFNVTKTMDTAKPVEKSLYTMVEKASLGTIVAIIVILLFLRNIRTTAISIISIPLSLLMALIALKLSDVSLNILTLGALTVAIGRVIDDSIVVVENIYRRLTDSEEQLKGENLIISATTEVFKPIMSSTLVTIIVFLPLVFVSGSVGEMFRPFALAIAFSLLASLLVSITLVPALAATLFKKGVKRRNKQHQEGLGVVSTTYKKVLHWSLNHKWIVIILSTLILVVTIVFGGPRLGTSFISAGDDKFLAITYTPKPGETEQAVLNHAKDVEKYLKQKKHVKTIQYSVGGSSPVDPTGSTNSMAIMVEYDNDTPNFDVEADKVIKHADGFKHPGEWKNQDLGTGAGNKSVEVTVKGPSMDAIKSTVKDIEQKMKQVKGLANVKSDLSQTYDQYEIKVDQNKAAENGISASQLAMHLNENLPEKTVTTVKENGKTVDVKVKQNKQTDWSEDKLNNITLKKPTGGTIKLGNIATLVKTTTPSKLTQEQGDYATTVSAKVTNKDVGGTTRQVMSKINNLDKPNNVKVNIGGASDDINNAMTQLAFAMLAAIIIVYLILVITFKGGLAPFTILFSLPFTVIGVIIALLITGETISVPSLIGMLMLIGIVVTNAIVLIDRVINNEQQGMEMKEALIEAGGTRIRPILMTAIATIGALVPLLFGQDSSILISKGLAATVIGGLISSTLLTLVVVPVIYEILFTLKKRFTKR
>NC_003923.1|WP_001161085.1|2328551_2328869_+|hypothetical-protein
MQFYLILLAILYLIVSFISIFKMEVVFTRILRIIMGVLLLFVLALTTMSFPKENWWVFIVLLLLVGNVEVTGFKMLKKDLKGVNILNLMSLFIFVIYFILTIVLF
>NC_003923.1|WP_000051210.1|2328142_2328307_+|hypothetical-protein
MSLENQLAELKYDYVRLQGDLEKRESLNLDTSALVRQLKDIENEIRNVRAQMQD
>NC_003923.1|WP_000230173.1|2337833_2338856_-|GTP-3',8-cyclase-MoaA
MVEQIKDKLGRPIRDLRLSVTDRCNFRCDYCMPKEVFGDDFVFLPKNELLTFDEMARIAKVYAELGVKKIRITGGEPLMRRDLDVLIAKLNQIDGIEDIGLTTNGLLLKKHGQKLYDAGLRRINVSLDAIDDTLFQSINNRNIKATTILEQIDYATSIGLNVKVNVVIQKGINDDQIIPMLEYFKDKHIEIRFIEFMDVGNDNGWDFSKVVTKDEMLTMIEQHFEIDPVEPKYFGEVAKYYRHKDNGVQFGLITSVSQSFCSTCTRARLSSDGKFYGCLFATVDGFNVKAFIRSGVTDEELKEQFKALWQIRDDRYSDERTAQTVANRQRKKINMNYIGG
>NC_003923.1|WP_000643988.1|2338875_2339475_-|molybdenum-cofactor-guanylyltransferase-MobA
MKAIILAGGHSVRFGKPKAFAEVNGETFYSRVIKTLESTNMFNEIIISTNAQLATQFKYPNVVIDDENHNDKGPLAGIYTIMKQHPEEELFFVVSVDTPMITGKAVSTLYQFLVSHLIENHLDVAAFKEDGRFIPTIAFYSPNALGAITKALHSDNYSFKNVYHELSTDYLDVRDVDAPSYWYKNINYQHDLDALIQKL
>NC_003923.1|WP_000866971.1|2339481_2339715_-|molybdopterin-converting-factor-subunit-1
MKVLYFAEIKDILQKAQEDIVLEQALTVQQFEDLLFERYPQINNKKFQVAVNEEFVQKSDFIQPNDTVALIPPVSGG
>NC_003923.1|WP_000808500.1|2339720_2340167_-|molybdenum-cofactor-biosynthesis-protein-MoaE
MKQFEIVTEPIQTEQYREFTINEYQGAVVVFTGHVREWTKGVKTEYLEYEAYIPMAEKKLAQIGDEINEKWPGTITSIVHRIGPLQISDIAVLIAVSSPHRKDAYRANEYAIERIKEIVPIWKKEIWEDGSKWQGHQKGNYEEAKREE
>NC_003923.1|WP_000602937.1|2340180_2340666_-|molybdopterin-guanine-dinucleotide-biosynthesis-protein-B
MILQIVGYKKSGKTTLMRHIVSFLKSHGYTVATIKHHGHGKEDIQLQDSDVDHMKHFEAGADQSIVQGFQYQQTVTRVDNQNLTQIIEKSVTIDTNIVLVEGFKNADFEKVVVYRNEEELQVLQQLSNVCYSINVREHEDFTAFEQWLLNKIKNDCDTQLT
>NC_003923.1|WP_000259724.1|2340662_2341922_-|molybdopterin-molybdotransferase-MoeA
MVVEKRNPIPVKEAIQRIVNQQSSMPAITVALEKSLNHILAEDIVATYDIPRFDKSPYDGFAIRSVDSQGASGQNRIEFKVIDHIGAGSVSDKLVGDHEAVRIMTGAQIPNGADAVVMFEQTIELEDTFTIRKPFSKNENISLKGEETTTGDVVLKKGQVINPGAIAVLATYGYAEVKVIKQPSVAVIATGSELLDVNDVLEDGKIRNSNGPMIRALAEKLGLEVGIYKTQKDDLDSGIQVVKEAMEKHDIVITTGGVSVGDFDYLPEIYKAVKAEVLFNKVAMRPGSVTTVAFVDGKYLFGLSGNPSACFTGFELFVKPAVKHMCGALEVFPQIIKATLMEDFTKANPFTRFIRAKATLTSAGATVVPSGFNKSGAVVAIAHANCMVMLPGGSRGFKAGHTVDIILTESDAAEEELLL
>NC_003923.1|WP_000134536.1|2341984_2342479_+|cyclic-pyranopterin-monophosphate-synthase-MoaC
MTEFTHINQQGHAKMVDVSDKQITKRTAVAHSSITVNKTIFKQISNNTNTKGNVLNTAQIAGIMAAKNTSTIIPMCHPLPLTGIDVHFSWDETNAPLYTLNIQTTVSTTGKTGVEMEALTAASATALTIYDMTKAVDKGMIIGETYLESKSGGKSGDFQRQSNQ
>NC_003923.1|WP_000503820.1|2342480_2342987_-|molybdenum-cofactor-biosynthesis-protein-MoaB
MGEHQNVKLNRTVKAAVLTVSDTRDFDTDKGGQCVRQLLQADDVEVSDAHYTIVKDEKVAITTQVKKWLEEDIDVIITTGGTGIAQRDVTIEAVKPLLTKEIEGFGELFRYLSYVEDVGTRALLSRAVAGTVNNKLIFSIPGSTGAVKLALEKLIKPELNHLIHELTK
>NC_003923.1|WP_000076923.1|2343017_2344022_-|ThiF-family-adenylyltransferase
MSQERYSRQILFKQIGEIGQSKINQKCALIIGMGALGTHVAEGLVRAGIAKLIIVDRDYIEFSNLQRQTLFTEEDALKMMPKVVAAKKHLLALRSDVDIDDYIAHVDYYFLETHGQDVDVIIDATDNFETRQLINDFAYKHRIPWIYGGVVQSTYTEAAFIPGKTPCFNCLVPQLPALNLTCDTVGVIQPAVTMATSLQLRDAMKVLTEQPIDTKITYGDIWDGSHYSFGFSKMQRSDCTTCGDVPSYPYLNKNEQRYATLCGRDTVQYENASITHDILVQFLKQHQLNYRSNSYMVMFEFKGHRIVAFKGGRFLIHGMTRTSDATHLMNLLFG
>NC_003923.1|WP_000913019.1|2344191_2344797_-|ATP-binding-cassette-domain-containing-protein
MLKINVKYQLKNTLIRINIDDTEPKIYAVRGPSGIGKTTVLNMIAGLRKADEAIIEVNGQLLTDTAKNVNVKIQQRRIGYLFQDYQLFPNMTVYKNITFMAEPSEHIDQLIQTLNIDHLMKQYPMTLSGGEAQRVALARALSTKPDLILLDEPFSSLDDTTKDESITLVKRIFNEWQIPIIFVTHSNYEAEQMAHEIITIG

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Crispr_ID: NC_003923_11

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_003923_11

2504458-2504536

Orphan

Consensus_repeat	Method
CCAACTTGCATTGTCTCTAGAAA	CRISPRCasFinder

1 spacers

The CRISPR arrays of NC_003923_11

>merge|NC_003923|11|2504458-2504536|CRISPRCasFinder
CCAACTTGCATTGTCTCTAGAAATTGGGAATCCAATTTCTCTTAGTTGGGACTCCGCCAACTTGCATTGTCTGTAGAAA

>NC_003923|11|10|2504458-2504536|CRISPRCasFinder
CCAACTTGCATTGTCTCTAGAAA	TTGGGAATCCAATTTCTCTTAGTTGGGACTCCG
CCAACTTGCATTGTCTGTAGAAA

Protein	Signature genes	Signature genes Name	Protein_function
NC_003923.1\|WP_001192075.1\|2507770_2508982_+\|multidrug-effflux-MFS-transporter	unknown	unknown	gnl\|CDD\|340878
NC_003923.1\|WP_000690199.1\|2510409_2511216_-\|metallophosphoesterase	unknown	unknown	gnl\|CDD\|163441
NC_003923.1\|WP_001176871.1\|2505727_2506870_+\|glycerate-kinase	unknown	unknown	gnl\|CDD\|272872
NC_003923.1\|WP_000482647.1\|2504842_2504950_-\|type-I-toxin-antitoxin-system-Fst-family-toxin	unknown	unknown	unknown
NC_003923.1\|WP_000971548.1\|2496060_2497176_-\|pyridoxal-phosphate-dependent-aminotransferase-family-protein	unknown	unknown	gnl\|CDD\|223234
NC_003923.1\|WP_000286878.1\|2495357_2496050_-\|6-carboxyhexanoate--CoA-ligase	unknown	unknown	gnl\|CDD\|224342
NC_003923.1\|WP_001046645.1\|2497153_2498161_-\|biotin-synthase-BioB	unknown	unknown	gnl\|CDD\|235755
NC_003923.1\|WP_000783428.1\|2493850_2494828_+\|bi-component-gamma-hemolysin-HlgAB/HlgCB-subunit-B	unknown	unknown	gnl\|CDD\|273388
NC_003923.1\|WP_000456497.1\|2509104_2509578_-\|AraC-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|226231
NC_003923.1\|WP_001793334.1\|2500239_2500407_-\|hypothetical-protein	unknown	unknown	unknown
NC_003923.1\|WP_001185692.1\|2513048_2515127_+\|sodium:proton-antiporter	unknown	unknown	gnl\|CDD\|223104
NC_003923.1\|WP_001080281.1\|2509690_2510347_+\|C39-family-peptidase	unknown	unknown	gnl\|CDD\|227323
NC_003923.1\|WP_000486494.1\|2500637_2502371_-\|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|224055
NC_003923.1\|WP_001110081.1\|2498162_2499521_-\|adenosylmethionine--8-amino-7-oxononanoate-transaminase	unknown	unknown	gnl\|CDD\|273109
NC_003923.1\|WP_000779360.1\|2505083_2505470_-\|flippase-GtxA	unknown	unknown	gnl\|CDD\|225155
NC_003923.1\|WP_001064815.1\|2502395_2504159_-\|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|224055
NC_003923.1\|WP_000101538.1\|2511501_2512911_+\|amino-acid-permease	unknown	unknown	gnl\|CDD\|224038
NC_003923.1\|WP_000831301.1\|2506929_2507589_+\|membrane-protein	unknown	unknown	gnl\|CDD\|222878
NC_003923.1\|WP_001217916.1\|2499498_2500185_-\|dethiobiotin-synthase	unknown	unknown	gnl\|CDD\|223210
NC_003923.1\|WP_000200943.1\|2494879_2495347_-\|QueT-transporter-family-protein	unknown	unknown	gnl\|CDD\|377623

Protein	Function_ID	Function_description	E-value
NC_003923.1\|WP_001192075.1\|2507770_2508982_+\|multidrug-effflux-MFS-transporter	gnl\|CDD\|340878	cd17320, MFS_MdfA_MDR_like, Multidrug transporter MdfA and similar multidrug resistance (MDR) transporters of the Major Facilitator Superfamily. This family is composed of bacterial multidrug resistance (MDR) transporters including several proteins from Escherichia coli such as MdfA (also called chloramphenicol resistance pump Cmr), EmrD, MdtM, MdtL, bicyclomycin resistance protein (also called sulfonamide resistance protein), and the uncharacterized inner membrane transport protein YdhC. EmrD is a proton-dependent secondary transporter, first identified as an efflux pump for uncouplers of oxidative phosphorylation. It expels a range of drug molecules and amphipathic compounds across the inner membrane of E. coli. Similarly, MdfA is a secondary multidrug transporter that exports a broad spectrum of structurally and electrically dissimilar toxic compounds. These MDR transporters are drug/H+ antiporters (DHA) belonging to the Major Facilitator Superfamily (MFS) of membrane transport proteins, which are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	3.81144e-73
NC_003923.1\|WP_000690199.1\|2510409_2511216_-\|metallophosphoesterase	gnl\|CDD\|163441	TIGR03729, acc_ester, putative phosphoesterase. Members of this protein family belong to the larger family pfam00149 (calcineurin-like phosphoesterase), a family largely defined by small motifs of metal-chelating residues. The subfamily in this model shows a good but imperfect co-occurrence in species with domain TIGR03715 that defines a novel class of signal peptide typical of the accessory secretory system.	1.39132e-107
NC_003923.1\|WP_001176871.1\|2505727_2506870_+\|glycerate-kinase	gnl\|CDD\|272872	TIGR00045, Glycerate_kinase, glycerate kinase. The only characterized member of this family so far is the glycerate kinase GlxK (EC 2.7.1.31) of E. coli. This enzyme acts after glyoxylate carboligase and 2-hydroxy-3-oxopropionate reductase (tartronate semialdehyde reductase) in the conversion of glyoxylate to 3-phosphoglycerate (the D-glycerate pathway) as a part of allantoin degradation. [Energy metabolism, Other].	0
NC_003923.1\|WP_000779360.1\|2505083_2505470_-\|flippase-GtxA	gnl\|CDD\|225155	COG2246, COG2246, Predicted membrane protein [Function unknown].	1.41026e-22
NC_003923.1\|WP_001046645.1\|2497153_2498161_-\|biotin-synthase-BioB	gnl\|CDD\|235755	PRK06256, PRK06256, biotin synthase; Validated.	0
NC_003923.1\|WP_000783428.1\|2493850_2494828_+\|bi-component-gamma-hemolysin-HlgAB/HlgCB-subunit-B	gnl\|CDD\|273388	TIGR01002, synergohymenotropic_toxin, beta-channel forming cytolysin. This family of cytolytic pore-forming proteins includes alpha toxin and leukocidin F and S subunits from Staphylococcus aureus, hemolysin II of Bacillus cereus, and related toxins. [Cellular processes, Toxin production and resistance].	5.50766e-128
NC_003923.1\|WP_000456497.1\|2509104_2509578_-\|AraC-family-transcriptional-regulator	gnl\|CDD\|226231	COG3708, COG3708, Uncharacterized protein conserved in bacteria [Function unknown].	2.01209e-37
NC_003923.1\|WP_000971548.1\|2496060_2497176_-\|pyridoxal-phosphate-dependent-aminotransferase-family-protein	gnl\|CDD\|223234	COG0156, BioF, 7-keto-8-aminopelargonate synthetase and related enzymes [Coenzyme metabolism].	3.62949e-138
NC_003923.1\|WP_001185692.1\|2513048_2515127_+\|sodium:proton-antiporter	gnl\|CDD\|223104	COG0025, NhaP, NhaP-type Na+/H+ and K+/H+ antiporters [Inorganic ion transport and metabolism].	2.07656e-103
NC_003923.1\|WP_001080281.1\|2509690_2510347_+\|C39-family-peptidase	gnl\|CDD\|227323	COG4990, COG4990, Uncharacterized protein conserved in bacteria [Function unknown].	2.51069e-72
NC_003923.1\|WP_000486494.1\|2500637_2502371_-\|ABC-transporter-ATP-binding-protein	gnl\|CDD\|224055	COG1132, MdlB, ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms].	6.79158e-143
NC_003923.1\|WP_001110081.1\|2498162_2499521_-\|adenosylmethionine--8-amino-7-oxononanoate-transaminase	gnl\|CDD\|273109	TIGR00508, hypothetical_protein_DESPIG_00326, adenosylmethionine-8-amino-7-oxononanoate transaminase. All members of the seed alignment have been demonstrated experimentally to act as EC 2.6.1.62, an enzyme in the biotin biosynthetic pathway. Alternate names include 7,8-diaminopelargonic acid aminotransferase, DAPA aminotransferase, and adenosylmethionine-8-amino-7-oxononanoate aminotransferase. The gene symbol is bioA in E. coli and BIO3 in S. cerevisiae. [Biosynthesis of cofactors, prosthetic groups, and carriers, Biotin].	0
NC_003923.1\|WP_000286878.1\|2495357_2496050_-\|6-carboxyhexanoate--CoA-ligase	gnl\|CDD\|224342	COG1424, BioW, Pimeloyl-CoA synthetase [Coenzyme metabolism].	3.89049e-130
NC_003923.1\|WP_001064815.1\|2502395_2504159_-\|ABC-transporter-ATP-binding-protein	gnl\|CDD\|224055	COG1132, MdlB, ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms].	5.9561e-146
NC_003923.1\|WP_000101538.1\|2511501_2512911_+\|amino-acid-permease	gnl\|CDD\|224038	COG1113, AnsP, Gamma-aminobutyrate permease and related permeases [Amino acid transport and metabolism].	0
NC_003923.1\|WP_000831301.1\|2506929_2507589_+\|membrane-protein	gnl\|CDD\|222878	PHA02562, 46, endonuclease subunit; Provisional.	0.00700231
NC_003923.1\|WP_001217916.1\|2499498_2500185_-\|dethiobiotin-synthase	gnl\|CDD\|223210	COG0132, BioD, Dethiobiotin synthetase [Coenzyme metabolism].	1.45777e-70
NC_003923.1\|WP_000200943.1\|2494879_2495347_-\|QueT-transporter-family-protein	gnl\|CDD\|377623	pfam06177, QueT, QueT transporter. This family includes the queT gene encoding a hypothetical integral membrane protein with 5 predicted transmembrane regions. The queT genes in Firmicutes are often preceded by the PreQ1 (7-aminomethyl-7-deazaguanine) riboswitches of two distinct classes, suggesting involvement of the QueT transporters in uptake of a queuosine biosynthetic intermediate.	0.00179995

>NC_003923.1|WP_001064815.1|2502395_2504159_-|ABC-transporter-ATP-binding-protein
MNNQTNWIKILSGFASDSKWKIMLSILLSIISVFSGLVPYWAVFKIILMMINNAYTINSIMVYIFIALIAYISQVCCFGASTMLSHITAYEILSEIRKKLAQKLMRLPLGVVESKKIGELKNIFVDKVETIELPLAHMIPEVIGNLLLSAAIFLYIMLIDWRMASALLVTIPISIFAFKKVMSGFNETYAEQMKSNNYMNSAIVEFIEGIEVIKTFNQSQSSYKKYKDAVDNYKIHTLNWFKNTWGYMNLGASVLPSTFLGILPVGMYLISINQLNYAEFFLCIVLSLGVVAPIKNFTNYVNHLKSIQYALTEVNQILSLEELVLSTKFKKPQHYEIAFNNVGFSYNKDKDDLVFKHLSFTVPENNFTAIVGASGSGKSTIAKLISRYWDVTSGEITIGGINIKDIESKQLNDLVGFVGQDNFLLNLTFKENIKLGNPEATDEAVEKAAKLAQCHEFIEKLPDGYDTNVGTVGDKLSGGEKQRVTIARMILKDAPIIVLDEATAYVDPDNEQKIQEALNVLTQDKTLIVIAHRLSTIQHADQIIVLGKQQILEKGSHHLLIKLNGNYKKMWDTHMHTKDWGINTGHN
>NC_003923.1|WP_000486494.1|2500637_2502371_-|ABC-transporter-ATP-binding-protein
MFQITFKILNWIRPYKARMILGFSMSFLNAIFIALPIFLAAKIFNNVLSHKPIYMKDILNVVIIMVLLVIGRFITAYFKSKSHESIAYEMSAKERLDIGDKLKNVRLGYFNSHHSNELTTIVTTDLTFLENFAMKMVDVVVNGYILITVLILSLLVVSWQVSLLACIGVLLSFFAIQLLERKSRQNAPAYHNVQNQLVEKVLEVIRGIQVIKSFAKENTSLKSFNQAVNESKRINTKIEMQYIPFNLLHLLSLKVVSIMIVLVACLLYMNHSIDLPTLIMISIFSFVIFDSVENINSAAHVLEMIDMTIDDIEKIKNAPELDENGKNLTIKNENIAFQNVNFSYDDKQVIKNVNFEIPTQTSTAIIGPSGSGKSTLCHLLLRFYDIDDGNIRIDGVDIKDMTLSTLMSKISAVFQKVYLFNDTIENNILFGNPGATKEEIIRAAKQACCHDFIMSLPEGYQTMLNEKGSNLSGGEKQRISIARAILKDAPIIILDEATASIDPENEQLIQTAINELSKGKTVITIAHKLETIKNADQIIVLNEGEIIQKGSHDELIRKPGMYQDFIRIKSKSAGWKL
>NC_003923.1|WP_001793334.1|2500239_2500407_-|hypothetical-protein
MQLLILTDIFYRIAVYICPNSLRSLSHFNSKVKILPKFIVILRSLNSSFLEKHAP
>NC_003923.1|WP_001217916.1|2499498_2500185_-|dethiobiotin-synthase
MRIFITSTNTDVGKTYVTKHLYHALKTRGHRVCIFKPFQTEERQDGTFPDLEVFKNECDLSYDITSLYTFKQPVSPHLAFKMTDQIFLNKQRVLDKVKVLDKEFDFILIEGAGGIAVPIYEGTDDFYMTKDLINDCADCVISVLPSKLGAISDAIVHQDYVNQNVSASNFLIMNRYTDSYIEKDNQITIGKLTNKTVYTFEEHATYENFSEAFLKQLIGVKNELHTTT
>NC_003923.1|WP_001110081.1|2498162_2499521_-|adenosylmethionine--8-amino-7-oxononanoate-transaminase
MNYTQQLKQKDSEYVWHPFTQMGVYSKEETIIIEKGKGSYLYDTNGNKYLDGYASLWVNVHGHNNKYLNKVIKKQLNKIAHSTLLGSSNIPSIELAEKLIEITPSNLRKVFYSDTGSASVEIAIKMAYQYWKNIDREKYAKKNKFITLNHGYHGDTIGAVSVGGIKTFHKIFKDLIFENIQVESPSFYRSNYDTENEMMTAILTNIEQILIERNDEIAGFILEPLIQGATGLFVHPKGFLKEVEKLCKKYDVLLICDEVAVGFGRTGKMFACNHEDVQPDIMCLGKAITGGYLPLAATLTSQKIYNAFLSDSHGVNTFFHGHTYTGNQIVCTVALENIRLYEKRKLLSHIETTSSTLEKQLHALKRHRNVGDVRGRGLMFGVELVTDKDSKTPLEIEKVERIVRKCKENGLMIRNLENVITFVPVLSMSNKEVKTMVRIFKKAVHNILDRKC
>NC_003923.1|WP_001046645.1|2497153_2498161_-|biotin-synthase-BioB
MNLAKRILQGEQLTKETVLKIYEDTNIDTLDLLNEAYILRKHYFGKKVKLNMILNAKSGICPENCGYCGQSRDIKQKQRYALIPEEQIIDGAKVAHDNHIGTYCIVMSGRGPSDKEVDHISNTVRTIKSQHPQLKICACLGLTNDEQAKKLKSAGVDRYNHNINTSENYHDNVVTTHSYKDRTDTIELMKANNISPCSGVICGMGESNQDIVDMAFALKEMDADSIPINFLHPIKGTKFGSMDDLTPMKCLRIVALFRLINPTKEIRIAGGREVNLRSLQPLALKAANSIFVGDYLITGGQPNQLDYDMINDLGFEIDYDTCENKENKNDVSRAN
>NC_003923.1|WP_000971548.1|2496060_2497176_-|pyridoxal-phosphate-dependent-aminotransferase-family-protein
MMFQEQIDLLQQKGLYRSLKSVGYIDRQYIEVENKRCTNYTSNDYLGLGQIAFDKDDFERFMRKYSYHLSSSRLISGSSTAYEEIETMLAGWLGYSACTILNSGYDANLALFNIFKNTNCVVFSDQENHASIIDGIKLSGLEKVIYKHLDIADLEKRLEKYPNQNIPKIIISDSAFSTNGDVVDIGQLVSLKHKYNATLILDVSHSFGIENYSNYQGVDILTSSLSKACGAYGGVILSSNDVKDMLINHGRPLIYSSSLPIYNLYFIKRNIEKLINADDRRTKLNSLSKYFNQKLKALNVNYNSSNSPIKFIEFDDIEAAENIHQTLLKHHVFTSYLRYPTVTKPMLRISLSYFHTEQDIDRLFEILHQED
>NC_003923.1|WP_000286878.1|2495357_2496050_-|6-carboxyhexanoate--CoA-ligase
MYSIKMRSSNQDVHISGAETICEFDKIEQTVQRFYNKGFFHENGQPDFLNIKIQKIMEPIQQIKALQIIEDDKANLQHLTQECGVTEQALNQGMTYIKNETVYTGAIILSAISGKRLDSFGQRGIRATHFSFEDINNKGDLNERVTDALAIASCINAHPYVKGELCVSDDLTYTTGYFASAKIGYHRLFDIKPVNTRYGGRIIFVDDRIDLNHYISFLESTPKQVVYERV
>NC_003923.1|WP_000200943.1|2494879_2495347_-|QueT-transporter-family-protein
MTSKDITQISVIAAILTILAALKIPSIIPGLDFQLSAPAALLILAFFGIKKYFLGGLLSSLLLLVFGVFNPINVIISIIFRVIAIAVVYLLKINVLSLVLASVLGSLVSRLLLSIILNLPVWVVLLNAIPGVIFTLIVAIPLYLTLRKRMAVLLR
>NC_003923.1|WP_000783428.1|2493850_2494828_+|bi-component-gamma-hemolysin-HlgAB/HlgCB-subunit-B
MKMNKLVKSSVATSMALLLLSGTANAEGKITPVSVKKVDDKVTLYKTTATADSDKFKISQILTFNFIKDKSYDKDTLVLKATGNINSGFVKPNPNDYDFSKLYWGAKYNVSISSQSNDSVNVVDYAPKNQNEEFQVQNTLGYTFGGDISISNGLSGGLNGNTAFSETINYKQESYRTTLSRNTNYKNVGWGVEAHKIMNNGWGPYGRDSFHPTYGNELFLAGRQSSAYAGQNFIAQHQMPLLSRSNFNPEFLSVLSHRQDGAKKSKITVTYQREMDLYQIRWNGFYWAGANYKNFKTRTFKSTYEIDWENHKVKLLDTKETENNK
>NC_003923.1|WP_000482647.1|2504842_2504950_-|type-I-toxin-antitoxin-system-Fst-family-toxin
MFNLLIDIMTSALSGCLVAFFAHWLRTRNNKKGDK
>NC_003923.1|WP_000779360.1|2505083_2505470_-|flippase-GtxA
MKLTQTHAEILKFIIVGGINTLNYYVVYLLLLKLLHIEYMISHITGFLVAFVISYYLNCYFVYRVKPTWRKFISFPITQIVNVSLQTVLLYVFVSWLNLPAEIAPFAGLVITIPITFVLSKWILKDSN
>NC_003923.1|WP_001176871.1|2505727_2506870_+|glycerate-kinase
MQLQKIVIAPDSFKESMTAQQVGNIIKQAFTNVYGNTLHYDIIPMADGGEGTTDALMHATGATKYTVIVNDPLMRPIEACYARADEQQIAIIEMAAASGLDLLEKEERNPLYTSSYGTGELIKDALNHGAKTIILGIGGSATNDGGTGMLSALGVQFTDVNGDLLQMNGANLAHIAQIDITNLDSRLKEVTFKVACDVSNPLLGENGATYIYGPQKGADAKMIPKLDFAMSHYHDKIKMCTGKSVNQIPGSGAAGGMGAALLAFCETTLTKGIDVVFDITDFHQRIKDADLVITGEGRMDYQTIFGKTPVGVALAAKQYHIPVIAICGSLGENYQHVYDFGIDSAYSIISSPSTLEDVLQNSEQNLLNTATDIARILKLQ
>NC_003923.1|WP_000831301.1|2506929_2507589_+|membrane-protein
MKRTDKYRDSYQYDNQNQNHRRQSEDASYRQQYAKGDPEEHPERYYNGRDYRREQILEEENEKSRRSKKWLYIIIAILLIIVAIFVTRALLNNDSDKVSNDPKVSQNYKKQVENQDGQINQQVDNAKENIKNNQKTDDIIKNLQNQIDNLKQQEQNKADSKLTQFYQDQINKLTEANNALKNNASQGKIESMLNDINTKFDSIKSKLESLFKDENGGAN
>NC_003923.1|WP_001192075.1|2507770_2508982_+|multidrug-effflux-MFS-transporter
MQSTKTKTKHFSFLLLITLGVMTAFGPLTIDMYVPSLPKVQGDFGSTTSEIQLTLSFTMIGLALGQFIFGPLSDAFGRKRIAVSILIIFILVSGLSMFVDQLPLFLTLRFIQGLTGGGVIVIAKASAGDKFSGNALAKFLASLMVVNGIITILAPLAGGLALSVATWRSIFTILTIVALIILIGVASQLPKTSKDELKQVNFSSVIKDFGSLLKKPAFIIPMLLQGLTYVMLFSYSSASPFITQKLYNMTPQQFSIMFAVNGVGLIIVSQVVALLVEKLHRHILLIILTIIQVVGVALIILTLTFHLPLWVLLIAFFLNVCPVTSIGPLGFTMAMEERTGGSGNASSLLGLFQFILGGAVAPLVGLKGEFNTSPYMIIIFITAILLVSLQIIYFKMIKKQHVA
>NC_003923.1|WP_000456497.1|2509104_2509578_-|AraC-family-transcriptional-regulator
MEYQLQQLASLTLVGIKETYENGRQAQQHIAGFWQRCYQEGVIADLQLKNNGDLAGILGLCISELDGKMSYMIAVTGDNSADIEKYDVITLASSKYMVFEAQGAVPKAVQQKMEEVHHYIHQYQADTVKSAPFFELYQDGDTTSEKYITEIWMPVKG
>NC_003923.1|WP_001080281.1|2509690_2510347_+|C39-family-peptidase
MNRKILPVKPISQLFPIPMVMGCEGVSAAMMLQYNNQHIPATEIMRHWPTHPNNPHKGYVGHHLFIKLGNYHQTIFPEAYVPFLQKYNPNIVDGTGKSLEDLKGIIDQGQPVLIYHTNLGSKPLLRVFRFDNKPAKQVSNIHVTLLIGYDDYYYYYIDPLWSHIRRGLVLPAIIPNRKQIIKIRKEKMEYSFNSPGRKCIYVQPHSYTIENQQQNKHT
>NC_003923.1|WP_000690199.1|2510409_2511216_-|metallophosphoesterase
MKIGTIADLHIDRHNKKTSEDYLEALVEIVKYKKLDILLIAGDISNHYQLTHQFITQLTKQLDIPVKFVPGNHDLWEVESMTTQDIWNNYKSMSQCLVGKPFIVNEEWAIIGHTGWYDYSFAAQRFSLEHLQKGKHYGATWQDKERISWGISDQNLSKIAAEQVKKDILEVGNRRVILVTHVVTHPDFIVPMPHRIFDFYNAFIGTSDFNPLYAMFDIPYSIMGHVHFRKSVIDDGRCYLCPCLGYPRQWRSEDIYQEINETIQIIEI
>NC_003923.1|WP_000101538.1|2511501_2512911_+|amino-acid-permease
MARKLHRELNNRHIQLIAIGGAIGTGLFLGSGQTISLTGPSLLFTYMIIGVVLFAFMRALGELLLSNTRFNSFVDIANEYLGPFGGFVIGWTYWLCWIVSSMSDLTAMGQYFAFWYPQVPNWITVLFIVLILISFNLLGARLFGELEFWFSIIKVVTIIAMVIVGLVLIFFSFKTHYGHASFTNLISHGGMFPGGTFGFLMSFQIAVYSFIGIELIGVTAGETKDPEKTLPKAINNVPIRILLFYIGGLLVIMSVIPWNDIDPNSSPFVKLFTLIGVPFAAGVVNFVVLTAAASATNSGIYSNSRILFGLSQQGLGPKVLNKTNSHGVPYLSMLVSSIALLIAALLNYIFPNAIQLFIYVTTLSTVLFLVVWAMIIVAYLMYLKKHPEAHKNSKFKLIGGKPIAYIILAFFFFVFILLFFSDETRAAIYISPFWFIFLFFFYKKYKTNAEKLAYEQRQNDSGHFRYDNQ
>NC_003923.1|WP_001185692.1|2513048_2515127_+|sodium:proton-antiporter
MALLEAFLIFIFAVIISSVINNRFPQIPTAFIQIALGVVIFIIPIQVDFQFNSEVFMFAVIAPLLFVEGTHVSRTKLLEYRKPILLMSMALVFATVVGVGYFIHWIWPALPMPAAFAIAAILCPTDAVAVSAITRGKLLPKGSMTILEGESLLNDAAGIISFKIAVTALVTGTFSLFQAVEQFIISTILGVLIGAIIGFVVVRIRIDLTANKGLKDNNTLTFIQLLTPFVVYFLAEEVHASGIIAVVIAGLIHGLERDRLIRAQTELQMNYHQIWNTFSYALNGFVFVVLGFMIPTVVIDIFQTEPDNFSFLIVITILIAIAIYACRFVWVYFWYKDFYFPKNIQSYLDEEHDSHETPPSRVRYAFIMTMCGIHGTISLSMALTLPFIITKGQAFEYRNDLLFIASFMVLISLILAQIVLPLITPSAEDTTFKGMTYQSAKIFIVQKVIQHFKNESKKDKNDTNYRPVLNQYYGELLFLLNSEPDNQNTKELKRLEDIAKVIETSTLERLIDKGKATYQDINNYRNIVELTETHRTASFVEKFANFFKMLWLRLKAMKHYKALNKESKKQEFENSFKDVQKIMRIVNHNIILRLKEEQNSTNVLEVSLVINHYYDMSRSLKWRAQRRKERQENSNQIIPQAMFHNHKLEALYLQRHLLDELIRKNKINNIVAAQIRENINYNEIVLSLQSKH

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Crispr_ID: NC_003923_12

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_003923_12

2644481-2644588

Orphan

Consensus_repeat	Method
ATTATTATAAATAATAAGTACACTACGGTTTACAGTTGG	CRISPRCasFinder

1 spacers

The CRISPR arrays of NC_003923_12

>merge|NC_003923|12|2644481-2644588|CRISPRCasFinder
ATTATTATAAATAATAAGTACACTACGGTTTACAGTTGGATCTTCGCTCCAACTGCATAAGAGCCACTAATTATTATAAATAATAAGTACACTACGGTTTACAGTTGG

>NC_003923|12|11|2644481-2644588|CRISPRCasFinder
ATTATTATAAATAATAAGTACACTACGGTTTACAGTTGG	ATCTTCGCTCCAACTGCATAAGAGCCACTA
ATTATTATAAATAATAAGTACACTACGGTTTACAGTTGG

Protein	Signature genes	Signature genes Name	Protein_function
NC_003923.1\|WP_001221402.1\|2641472_2641664_+\|cell-wall-inhibition-responsive-protein-CwrA	unknown	unknown	unknown
NC_003923.1\|WP_000076661.1\|2644660_2644867_+\|copper-chaperone-CopZ	unknown	unknown	gnl\|CDD\|225328
NC_003923.1\|WP_000160454.1\|2651111_2652605_-\|NAD(P)/FAD-dependent-oxidoreductase	unknown	unknown	gnl\|CDD\|224154
NC_003923.1\|WP_000725225.1\|2653260_2654028_-\|CHAP-domain-containing-protein	unknown	unknown	gnl\|CDD\|226451
NC_003923.1\|WP_000686167.1\|2647558_2649067_-\|NAD(P)/FAD-dependent-oxidoreductase	unknown	unknown	gnl\|CDD\|224154
NC_003923.1\|WP_000432897.1\|2632914_2634909_-\|ferrous-iron-transport-protein-B	unknown	unknown	gnl\|CDD\|223447
NC_003923.1\|WP_000932073.1\|2634920_2635148_-\|ferrous-iron-transport-protein-A	unknown	unknown	gnl\|CDD\|224830
NC_003923.1\|WP_000379821.1\|2654388_2656200_-\|acetyltransferase	unknown	unknown	gnl\|CDD\|224748
NC_003923.1\|WP_000178307.1\|2649078_2649942_-\|phytoene/squalene-synthase-family-protein	unknown	unknown	gnl\|CDD\|224478
NC_003923.1\|WP_000625079.1\|2645977_2647132_-\|aminotransferase-class-I/II-fold-pyridoxal-phosphate-dependent-enzyme	unknown	unknown	gnl\|CDD\|181219
NC_003923.1\|WP_000259685.1\|2638900_2640445_-\|L-glutamate-gamma-semialdehyde-dehydrogenase	unknown	unknown	gnl\|CDD\|179543
NC_003923.1\|WP_000871731.1\|2649978_2651106_-\|glycosyltransferase-family-2-protein	unknown	unknown	gnl\|CDD\|132997
NC_003923.1\|WP_001795496.1\|2652597_2653086_-\|glycosyl-4,4'-diaponeurosporenoate-acyltransferase	unknown	unknown	unknown
NC_003923.1\|WP_000136500.1\|2640634_2641234_-\|sugar-O-acetyltransferase	unknown	unknown	gnl\|CDD\|100047
NC_003923.1\|WP_001796738.1\|2638621_2638789_-\|hypothetical-protein	unknown	unknown	unknown
NC_003923.1\|WP_001051422.1\|2635363_2637853_-\|fatty-acid-efflux-MMPL-transporter-FarE	unknown	unknown	gnl\|CDD\|225272
NC_003923.1\|WP_000111118.1\|2632731_2632902_-\|FeoB-associated-Cys-rich-membrane-protein	unknown	unknown	gnl\|CDD\|378908
NC_003923.1\|WP_000665232.1\|2637997_2638546_+\|fatty-acid-efflux-pump-transcriptional-regulator-FarR	unknown	unknown	gnl\|CDD\|224228
NC_003923.1\|WP_000024129.1\|2641903_2644312_+\|copper-translocating-P-type-ATPase	unknown	unknown	gnl\|CDD\|319783
NC_003923.1\|WP_000161366.1\|2644956_2645955_-\|D-lactate-dehydrogenase	unknown	unknown	gnl\|CDD\|181499

Protein	Function_ID	Function_description	E-value
NC_003923.1\|WP_000076661.1\|2644660_2644867_+\|copper-chaperone-CopZ	gnl\|CDD\|225328	COG2608, CopZ, Copper chaperone [Inorganic ion transport and metabolism].	3.85103e-21
NC_003923.1\|WP_000160454.1\|2651111_2652605_-\|NAD(P)/FAD-dependent-oxidoreductase	gnl\|CDD\|224154	COG1233, COG1233, Phytoene dehydrogenase and related proteins [Secondary metabolites biosynthesis, transport, and catabolism].	8.07149e-132
NC_003923.1\|WP_000686167.1\|2647558_2649067_-\|NAD(P)/FAD-dependent-oxidoreductase	gnl\|CDD\|224154	COG1233, COG1233, Phytoene dehydrogenase and related proteins [Secondary metabolites biosynthesis, transport, and catabolism].	1.03717e-133
NC_003923.1\|WP_000432897.1\|2632914_2634909_-\|ferrous-iron-transport-protein-B	gnl\|CDD\|223447	COG0370, FeoB, Fe2+ transport system protein B [Inorganic ion transport and metabolism].	0
NC_003923.1\|WP_000932073.1\|2634920_2635148_-\|ferrous-iron-transport-protein-A	gnl\|CDD\|224830	COG1918, FeoA, Fe2+ transport system protein A [Inorganic ion transport and metabolism].	9.02667e-20
NC_003923.1\|WP_000379821.1\|2654388_2656200_-\|acetyltransferase	gnl\|CDD\|224748	COG1835, COG1835, Predicted acyltransferases [Lipid metabolism].	6.58134e-84
NC_003923.1\|WP_000178307.1\|2649078_2649942_-\|phytoene/squalene-synthase-family-protein	gnl\|CDD\|224478	COG1562, ERG9, Phytoene/squalene synthetase [Lipid metabolism].	2.37403e-100
NC_003923.1\|WP_000625079.1\|2645977_2647132_-\|aminotransferase-class-I/II-fold-pyridoxal-phosphate-dependent-enzyme	gnl\|CDD\|181219	PRK08068, PRK08068, transaminase; Reviewed.	2.7078e-143
NC_003923.1\|WP_000161366.1\|2644956_2645955_-\|D-lactate-dehydrogenase	gnl\|CDD\|181499	PRK08605, PRK08605, D-lactate dehydrogenase; Validated.	0
NC_003923.1\|WP_000871731.1\|2649978_2651106_-\|glycosyltransferase-family-2-protein	gnl\|CDD\|132997	cd00761, Glyco_tranf_GTA_type, Glycosyltransferase family A (GT-A) includes diverse families of glycosyl transferases with a common GT-A type structural fold. Glycosyltransferases (GTs) are enzymes that synthesize oligosaccharides, polysaccharides, and glycoconjugates by transferring the sugar moiety from an activated nucleotide-sugar donor to an acceptor molecule, which may be a growing oligosaccharide, a lipid, or a protein. Based on the stereochemistry of the donor and acceptor molecules, GTs are classified as either retaining or inverting enzymes. To date, all GT structures adopt one of two possible folds, termed GT-A fold and GT-B fold. This hierarchy includes diverse families of glycosyl transferases with a common GT-A type structural fold, which has two tightly associated beta/alpha/beta domains that tend to form a continuous central sheet of at least eight beta-strands. The majority of the proteins in this superfamily are Glycosyltransferase family 2 (GT-2) proteins. But it also includes families GT-43, GT-6, GT-8, GT13 and GT-7; which are evolutionarily related to GT-2 and share structure similarities.	9.85714e-23
NC_003923.1\|WP_000136500.1\|2640634_2641234_-\|sugar-O-acetyltransferase	gnl\|CDD\|100047	cd03357, LbH_MAT_GAT, Maltose O-acetyltransferase (MAT) and Galactoside O-acetyltransferase (GAT): MAT and GAT catalyze the CoA-dependent acetylation of the 6-hydroxyl group of their respective sugar substrates. MAT acetylates maltose and glucose exclusively at the C6 position of the nonreducing end glucosyl moiety. GAT specifically acetylates galactopyranosides. Furthermore, MAT shows higher affinity toward artificial substrates containing an alkyl or hydrophobic chain as well as a glucosyl unit. Active MAT and GAT are homotrimers, with each subunit consisting of an N-terminal alpha-helical region and a C-terminal left-handed parallel alpha-helix (LbH) subdomain with 6 turns, each containing three imperfect tandem repeats of a hexapeptide repeat motif (X-[STAV]-X-[LIV]-[GAED]-X).	5.94515e-91
NC_003923.1\|WP_000259685.1\|2638900_2640445_-\|L-glutamate-gamma-semialdehyde-dehydrogenase	gnl\|CDD\|179543	PRK03137, PRK03137, 1-pyrroline-5-carboxylate dehydrogenase; Provisional.	0
NC_003923.1\|WP_001051422.1\|2635363_2637853_-\|fatty-acid-efflux-MMPL-transporter-FarE	gnl\|CDD\|225272	COG2409, COG2409, Predicted drug exporters of the RND superfamily [General function prediction only].	1.58078e-171
NC_003923.1\|WP_000111118.1\|2632731_2632902_-\|FeoB-associated-Cys-rich-membrane-protein	gnl\|CDD\|378908	pfam12669, P12, Virus attachment protein p12 family. This family of proteins are related to Virus attachment protein p12 from the African swine fever virus. The family appears to contain an N-terminal signal peptide followed by a short cysteine rich region. The cysteine rich region is extremely variable and it is possible that only the N-terminal region is homologous.	0.00119197
NC_003923.1\|WP_000665232.1\|2637997_2638546_+\|fatty-acid-efflux-pump-transcriptional-regulator-FarR	gnl\|CDD\|224228	COG1309, AcrR, Transcriptional regulator [Transcription].	8.81924e-09
NC_003923.1\|WP_000024129.1\|2641903_2644312_+\|copper-translocating-P-type-ATPase	gnl\|CDD\|319783	cd02094, P-type_ATPase_Cu-like, P-type heavy metal-transporting ATPase, similar to human copper-transporting ATPases, ATP7A and ATP7B. The mammalian copper-transporting P-type ATPases, ATP7A and ATP7B are key molecules required for the regulation and maintenance of copper homeostasis. Menkes and Wilson diseases are caused by mutation in ATP7A and ATP7B respectively. This subfamily includes other copper-transporting ATPases such as: Bacillus subtilis CopA , Archeaoglobus fulgidus CopA, and Saccharomyces cerevisiae Ccc2p. This subclass of P-type ATPase is also referred to as CPx-type ATPases because their amino acid sequences contain a characteristic CPC or CPH motif associated with a stretch of hydrophobic amino acids and N-terminal ion-binding sequences. This subfamily belongs to the P-type ATPases, a large family of integral membrane transporters that are of critical importance in all kingdoms of life. They generate and maintain (electro-) chemical gradients across cellular membranes, by translocating cations, heavy metals and lipids, and are distinguished from other main classes of transport ATPases (F- , V- , and ABC- type) by the formation of a phosphorylated (P-) intermediate state in the catalytic cycle.	0
NC_003923.1\|WP_000725225.1\|2653260_2654028_-\|CHAP-domain-containing-protein	gnl\|CDD\|226451	COG3942, COG3942, Surface antigen [General function prediction only].	1.53845e-31

>NC_003923.1|WP_000024129.1|2641903_2644312_+|copper-translocating-P-type-ATPase
MANTKKTTLDITGMTCAACSNRIEKKLNKLDDVNAQVNLTTEKATVEYNPDQHDVQEFINTIQHLGYGVAVETVELDITGMTCAACSSRIEKVLNKMDGVQNATVNLTTEQAKVDYYPEETDADKLVTRIQKLGYDASIKDNNKDQTSRKAEALQHKLIKLIISAVLSLPLLMLMFVHLFNMHIPALFTNPWFQFILATPVQFIIGWQFYVGAYKNLRNGGANMDVLVAVGTSAAYFYSIYEMVRWLNGSTTQPHLYFETSAVLITLILFGKYLEARAKSQTTNALGELLSLQAKEARILKDGNEVMIPLNEVHVGDTLIVKPGEKIPVDGKIIKGMTAIDESMLTGESIPVEKNVDDTVIGSTMNKNGTITMTATKVGGDTALANIIKVVEEAQSSKAPIQRLADIISGYFVPIVVGIALLTFIVWITLVTPGTFEPALVASISVLVIACPCALGLATPTSIMVGTGRAAENGILFKGGEFVERTHQIDTIVLDKTGTITNGRPVVTDYHGDNQTLQLLATAEKDSEHPLAEAIVNYAKEKQLTLTETTTFKAVPGHGIEATIDHHHILVGNRKLMADNDISLPKHISDDLTYYERDGKTAMLIAVNYSLTGIIAVADTVKDHAKDAIKQLHDMGIEVAMLTGDNKNTAQAIAKQVGIDTVIADILPEEKAAQIAKLQQQGKKVAMVGDGVNDAPALVKADIGIAIGTGTEVAIEAADITILGGDLMLIPKAIYASKATIRNIRQNLFWAFGYNIAGIPIAALGLLAPWVAGAAMALSSVSVVTNALRLKKMRLEPRRKDA
>NC_003923.1|WP_001221402.1|2641472_2641664_+|cell-wall-inhibition-responsive-protein-CwrA
MRILITGTVAILIILGLVKTIQDHEMTNDTSRQLSDNKDDDKVIHLNNFKNLHAKEFNPSDFF
>NC_003923.1|WP_000136500.1|2640634_2641234_-|sugar-O-acetyltransferase
MTEKEKMLAEKWYDANFDQYLINERARAKDICFELNHTRPSATNKRKELIDQLFQTTTDNVSISIPFDTDYGWNVKLGKNVYVNTNCYFMDGGQITIGDNVFIGPNCGFYTATHPLNFHHRNEGFEKAGPIHIGSNTWFGGHVAVLPGVTIGEGSVIGAGSVVTKDIPPHSLAVGNPCKVVRKIDNDLPSETLNDETIK
>NC_003923.1|WP_000259685.1|2638900_2640445_-|L-glutamate-gamma-semialdehyde-dehydrogenase
MVVEFKNEPGYDFSVQENVDMFKKALKDVEKELGQDIPLVINGEKIFKDDKIKSINPADTSQVIANASKATKQDVEDAFKAADEAYKSWKTWSANDRAELMLRVSAIIRRRKAEIAAIMVYEAGKPWDEAVGDAAEGIDFIEYYARSMMDLAQGKPVLDREGEHNKYFYKSIGTGVTIPPWNFPFAIMAGTTLAPVVAGNTVLLKPAEDTPYIAYKLMEILEEAGLPKGVVNFVPGDPKEIGDYLVDHKDTHFVTFTGSRATGTRIYERSAVVQEGQNFLKRVIAEMGGKDAIVVDENIDTDMAAEAIVTSAFGFSGQKCSACSRAIVHKDVYDEVLEKSIKLTKELTLGNTVDNTYMGPVINKKQFDKIKNYIEIGKEEGKLEQGGGTDDSKGYFVEPTIISGLKSKDRIMQEEIFGPVVGFVKVNDFDEAIEVANDTDYGLTGAVITNNREHWIKAVNEFDVGNLYLNRGCTSAVVGYHPFGGFKMSGTDAKTGSPDYLLHFLEQKVVSEMF
>NC_003923.1|WP_001796738.1|2638621_2638789_-|hypothetical-protein
MRYVISIIMGIVLAIWSFKQLSQSHLDSGFIFFFIVYVLCISYFNSDKHDKNKKR
>NC_003923.1|WP_000665232.1|2637997_2638546_+|fatty-acid-efflux-pump-transcriptional-regulator-FarR
MKETDLRVIKTKKALSSSLLQLLEQQLFQTITVNQICDNALVHRTTFYKHFYDKYDLLEYLFNQLTKDYFARDISDRLNHPFQTISDTINNKEDLRDIAEFQEEDAEFNKVLKNVCIKIMHNDIKNNRDRIDIDSDIPDNLIFYIYDSLIEGFMHWIKDEKIDWPGEEIDKIFHKVINIKIK
>NC_003923.1|WP_001051422.1|2635363_2637853_-|fatty-acid-efflux-MMPL-transporter-FarE
MAKFLYKMGTFIAKHKWSAVIAWIVIVAAILIPLATNAPKFDNDIKMTGLESLDTNKKIEKHFNQDSEKAQIRVVFKTTKDDGIVQPNITKDIKKTLDDIKKDDKHIDKISDPYENKQISKDKTTAFADITYDVSQTSLKDGSRDNVKSHLKDLRDNHNVQTELTGTGMTSTEVGGNSELVGIIVAFVVLLITFGSVIAAGLPIISALIGLASGVGIISLLTYAFDIPNVTLTLAVMIGLAVGIDYALFILFRYRQVMKTETDYIKGIGLAIGTAGSAVIFAGVTVVIAVCGLSLVGIDFLAVMGFASAISVIFAVFSALTLLPALISIFHKRIKVNKLQSNFKKDIDTPWSKFITGNALAAVLLGLIILVAAAIPVSHMRLGIPDDGVKPADSTQKKAYDIISDKFGEGFNGQIPMLINVKDKKDDPQGLQQDLQSVYKDIKDKKNVDIVTPPQMSKDNDYALMVVIPKKGPNAESTNDLVHDLRDYHKDAQDKYGFKTEISGQSVINIDMSKKLNEAIPLFATVIVVLAFFLLMIVFRSILIPLKAVLGFVLSLMATLGFTTLVMQDGFMKGLFGIETTGPMLAFLPVITIGILFGLAMDYEVFLMSRIHEEYSKTGDNDYSIKVGLKESGPVIVAAALIMFSVFFAFVFQEDVMIKSMGMALAFGVLFDAFVVRMMLIPALTKLFGKGSWYLPAWLNRIIPRVDIEGHALEKYKTVESQESEAKDSKETYDTTFKIYPQGATNVSKHQDVHGQDDVRSIVLDDKTMALYQEVKQQSASSFFLYDALIDYQNKHQLNSKQQVTNIEQLNKNIEKLNQLLEKNLRNKS
>NC_003923.1|WP_000932073.1|2634920_2635148_-|ferrous-iron-transport-protein-A
MLNIKNGEMNKAYKIKRMDIANENMLYRLSAFGLTDDAIITIKQKCLFKGPCIIEVNGQQLSIRHCDACSIALEE
>NC_003923.1|WP_000432897.1|2632914_2634909_-|ferrous-iron-transport-protein-B
MENYCILGNPNVGKTSLFNALTGSYEYIGNWSGVTVEKKVGKLKENVGQLIDLPGTYDLSPISKDETVVTDYLLNDSFSGIINIVDASQLKRNMQLTVQLLELNQPIYIGLNMIDVATKRGIKIDYHKLMKKLKTPIFPVVARTGKGTKHLLGEIKHLGEGYQPHFKINYGEKIEETIKNMCQIIMTETSHDKYQARFIAIQFLLNNMQIANELNSEVVNKLSSLRDQVDKQVEAVSVRREMERIRNHYIETLLQDVVTYPDEDKQYFSSRIDKILTHKYIGMPIFLAIMWLIFQTTFTWIGTPLSDQLDAFIGGTFTDSVKTIMNYLGVIPFLQDLITDGIIAGVGSVLVFVPQIVVLFFFISLLEDSGYMARIAVLMDRIMESFGLSGKSFIPMIIGFGCNVPSIMAARSIENEKERLTTILIAPFMSCSARLPVYALFVGIFFKENQSLVVLSLYVLGIIMAFLVSTVLTKTILKNDNAIFIVELPTYRVPSIKTLWRSTWEKAKGFVRKAGTFIFGGSVVIWLLSYVGPHGINVNINQSFLHMVGSFFGMLVQPLGFGTWQAGATLVPGFLAKEVIVSSMAIIYSSGDAGLVNVIQNQFTPLSAYAFMIFILLYIPCVSTVAAIRKETYSWKWTALAVVYPLVTAYVLTFIFYQIGHLFV
>NC_003923.1|WP_000111118.1|2632731_2632902_-|FeoB-associated-Cys-rich-membrane-protein
MSVIINILIFLAIFGYALYTLVKFFKRSKQGKCGTCDINRDCCGTEQHTANHFPGK
>NC_003923.1|WP_000076661.1|2644660_2644867_+|copper-chaperone-CopZ
MSQEILNVEGMSCGHCKSAVESALNNIDGVTSADVNLENGQVSVQYDDSKVAVSQMKDAIEDQGYDVV
>NC_003923.1|WP_000161366.1|2644956_2645955_-|D-lactate-dehydrogenase
MTKIKIMSVRDEDMPYIKAWAEKHHVEVDITKEALTDDNVEGVAGYDGLSLSQQIPLSEHVYKRLNELGIKQIAQRSAGFDTYDLELANKYNLIVSNVPSYSPNSIAEFAVNQAINVVRHFNQIQTKVREHDFRWEPTILSKSIKDLKVAVIGTGRIGRVVADIFANGYQSDVVAYDPFPNAKIATYVDYKDTIEEAVEGADIVTLHVPATKYNHYLFNAELFKHFKKGAVFVNCARGSLVDTKALLDALDNGVIKGAALDTYEFERKLFPSDQRGKTLNDPLLESLIDREDVILTPHIAFYTEAAVKNLIVDALDATLDVLQTGDTRLRVN
>NC_003923.1|WP_000625079.1|2645977_2647132_-|aminotransferase-class-I/II-fold-pyridoxal-phosphate-dependent-enzyme
MISNKLANIPDSYFGKTMGRKIEHGPLPLINMAVGIPDGPTPQGIIDHFQQALTIPENQKYGAFHGKEAFKQAIVDFYQRQYNVTLDKEDEVCILYGTKNGLVAVPTCVINPGDYVLLPDPGYTDYLAGVLLADGKPVPLNLEPPHYLPDWSTVDSQIIDKTKLIYLTYPNNPTGSTATKEVFDEAIAKFKDTDTKIVHDFAYGAFGFDAKNPSILASENGKDVAIEIYSLSKGYNMSGFRVGFAVGNKDMIQALKKYQTHTNAGMFGALQDAAIYALNHYDDFLEEQSNVFKTRRDRFEAMLAKADLPFVHAKGGIYVWLETPPGYDSEQFEQFLVQEKSILVAPGKPFGENGNRYVRISLALDDQKLDEAAIRLTELAYLYE
>NC_003923.1|WP_000686167.1|2647558_2649067_-|NAD(P)/FAD-dependent-oxidoreductase
MKIAVIGAGVTGLAAAARIASQGHEVTIFEKNNNVGGRMNQLKKDGFTFDMGPTIVMMPDVYKDVFTACGKNYEDYIELRQLRYIYDVYFDHDDRITVPTDLAELQQMLESIEPGSTHGFMSFLTDVYKKYEIARRYFLERTYRKPSDFYNMTSLVQGAKLKTLNHADQLIEHYIDNEKIQKLLAFQTLYIGIDPKRGPSLYSIIPMIEMMFGVHFIKGGMYGMAQGLAQLNKDLGVNIELNAEIEQIIIDPKFKRADAIKVNGDIRKFDKILCTADFPSVAESLMPDFAPIKKYPPHKIADLDYSCSAFLMYIGIDIDVTDQVRLHNVIFSDDFRGNIEEIFEGRLSYDPSIYVYVPAVADKSLAPEGKTGIYVLMPTPELKTGSGIDWSDEALTQQIKEIIYRKLATIEVFEDIKSHIVSETIFTPNDFEQTYHAKFGSAFGLMPTLAQSNYYRPQNVSRDYKDLYFAGASTHPGAGVPIVLTSAKITVDEMIKDIEQGV
>NC_003923.1|WP_000178307.1|2649078_2649942_-|phytoene/squalene-synthase-family-protein
MTMMDMNFKYCHKIMKKHSKSFSYAFDLLPEDQRKAVWAIYAVCRKIDDSIDVYGDIQFLNQIKEDIQSIEKYPYEHHHFQSDRRIMMALQHVAQHKNIAFQSFYNLIDTVYKDQHFTMFETDAELFGYCYGVAGTVGEVLTPILSDHETHQTYDVARRLGESLQLINILRDVGEDFDNERIYFSKQRLKQYEVDIAEVYQNGVNNHYIDLWEYYAAIAEKDFQDVMDQIKVFSIEAQPIIELAARIYIEILDEVRQANYTLHERVFVDKRKKAKLFHEINSKYHRI
>NC_003923.1|WP_000871731.1|2649978_2651106_-|glycosyltransferase-family-2-protein
MKWLSRILTVIVTMSMACGALIFNRRHQLKAKTLNFNHKALTIIIPARNEEKRIGHLLHSIIQQQVPVDVIVMNDGSTDETARVARSYGATVVDVVDDTDGKWYGKSHACYQGVTHACTNRIAFVDADVTFLRKDAVETLINQYQLQGEKGLLSVQPYHITKRFYEGFSAIFNLMTVVGMNVFSTLDDGRTNQHAFGPVTLTNKEDYYATGGHKSANRHIIEGFALGSAYTSQSLPVTVYEGFPFVAFRMYQEGFQSLQEGWTKHLSTGAGGTKPKIMTAIVLWLFGSIASILGLCLSLKYRQMSVRKMVALYLSYTTQFIYLHRRVGQFSNLLMVCHPLLFMFFTKIFIQSWKQTHRYGVVEWKGRQYSISKEQ
>NC_003923.1|WP_000160454.1|2651111_2652605_-|NAD(P)/FAD-dependent-oxidoreductase
MTKHIIVIGGGLGGISAAIRMAQSGYSVSLYEQNNHIGGKVNRHESDGFGFDLGPSILTMPYIFEKLFEYSKKQMSDYVTIKRLPHQWRSFFPDGTTIDLYEGIKETGQHNAILSKQDIEELQNYLNYTRRIDRITEKGYFNYGLDTLSQIIKFHGPLNALINYDYVHTMQQAIDKRISNPYLRQMLGYFIKYVGSSSYDAPAVLSMLFHMQQEQGLWYVEGGIHHLANALEKLAREEGVTIHTGARVDNIKTYQRRVTGVRLDTGEFVKADYIISNMEVIPTYKYLIHLDTQRLNKLEREFEPASSGYVMHLGVACQYPQLAHHNFFFTENAYLNYQQVFHEKVLPDDPTIYLVNTNKTDHTQAPVGYENIKVLPHIPYIQDQPFTTEDYAKFRDKILDKLEKMGLTDLRKHIIYEDVWTPEDIEKNYRSNRGAIYGFVADKKKNKGFKFPKESQYFENLYFVGGSVNPGGGIPMVTLSGQQVADKINAREAKNRK
>NC_003923.1|WP_001795496.1|2652597_2653086_-|glycosyl-4,4'-diaponeurosporenoate-acyltransferase
MKKYIKTAFFCSMYWLIVQLNIANLGTRIPDKYFRQKYIIFKSFNFEKHGKFWNKWFYVRKWKHKILDGHQLNQNIYDQRHLMTINTDEIEKMIIETKRAELIHWISILPVIIFNKGPRLVKYINIFYAMIANVPIIIVQRYNRPRLTQLLRILKRRGERHD
>NC_003923.1|WP_000725225.1|2653260_2654028_-|CHAP-domain-containing-protein
MKKIVTATIATAGLATIAFAGHDAQAAEQNNNGYNSNDAQSYSYTYTIDAQGNYHYTWTGNWNPSQLTQNNTYYYNNYNTYSYNNASYNNYYNHSYQYNNYTNNSQTATNNYYTGGSGASYSTTSNNVHVTTTAAPSSNGRSISNGYASGSNLYTSGQCTYYVFDRVGGKIGSTWGNASNWANAAASSGYTVNNTPKVGAIMQTTQGYYGHVAYVEGVNSNGSVRVSEMNYGHGAGVVTSRTISANQAGSYNFIH
>NC_003923.1|WP_000379821.1|2654388_2656200_-|acetyltransferase
MDTKDFKRLEKMYSPRYLPGLDGLRAFAVIGIIIYHLNAQWLSGGFLGVDTFFVISGYLITSLLISEYYRTQKIDLLEFWKRRLKRLIPAVLFLICVVLTFTLIFKPELIIQMKRDAIAAIFYVSNWWYISQNVDYFNQFAIEPLKHLWSLAIEEQFYLLFPLVITFLLHRFKPRNIIQTLFIVSLISLGLMIVIHFITGDNSRVYFGTDTRLQTLLLGCILAFIWPPFALKKDISKKIVVSLDIIGISGFAVLMTLFFIVGDQDQWIYNGGFYIISFATLFIIAIAVHPSSLFAKFLSMKPLLIIGKRSYSLYLWHYPIIVFVNSYYVQGQIPVYVYIIEILLTALMAEISYRFIETPIRKKGFKAFAFLPKKKGQFARTVLVILLLVPSIVVLSGQFDALGKQHEAEKKEKKTEFKTTKKKVVKKDKQEDKQTANSKEDIKKSSPLLIGDSVMVDIGNVFTKKIPNAQIDGKVGRQLVDATPIVKSQYKDYAKKGQKVVVELGTNGAFTKDQLNELLDSFGKADIYLVSIRVPRDYEGRINKLIYEAAEKRSNVHLVDWYKASAGHPEYFAYDGIHLEYAGSKALTDLIVKTMETHATNKK

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Click the colored protein region to show detailed information

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity
NC_003923_1	1.1\|166843\|33\|NC_003923\|CRISPRCasFinder	166843-166875	33	NC_003923.1	1067886-1067918	0	1.0
NC_003923_1	1.1\|166843\|33\|NC_003923\|CRISPRCasFinder	166843-166875	33	NC_003923.1	1440645-1440677	0	1.0
NC_003923_1	1.1\|166843\|33\|NC_003923\|CRISPRCasFinder	166843-166875	33	NC_003923.1	1992728-1992760	0	1.0
NC_003923_2	2.2\|290181\|31\|NC_003923\|CRT	290181-290211	31	NC_003923.1	141481-141511	0	1.0
NC_003923_2	2.2\|290181\|31\|NC_003923\|CRT	290181-290211	31	NC_003923.1	166797-166827	0	1.0
NC_003923_2	2.2\|290181\|31\|NC_003923\|CRT	290181-290211	31	NC_003923.1	819320-819350	0	1.0
NC_003923_2	2.2\|290181\|31\|NC_003923\|CRT	290181-290211	31	NC_003923.1	875751-875781	0	1.0
NC_003923_2	2.2\|290181\|31\|NC_003923\|CRT	290181-290211	31	NC_003923.1	924483-924513	0	1.0
NC_003923_2	2.2\|290181\|31\|NC_003923\|CRT	290181-290211	31	NC_003923.1	1041765-1041795	0	1.0
NC_003923_2	2.2\|290181\|31\|NC_003923\|CRT	290181-290211	31	NC_003923.1	1041881-1041911	0	1.0
NC_003923_2	2.2\|290181\|31\|NC_003923\|CRT	290181-290211	31	NC_003923.1	1350827-1350857	0	1.0
NC_003923_2	2.2\|290181\|31\|NC_003923\|CRT	290181-290211	31	NC_003923.1	1440751-1440781	0	1.0
NC_003923_2	2.2\|290181\|31\|NC_003923\|CRT	290181-290211	31	NC_003923.1	1483471-1483501	0	1.0
NC_003923_2	2.2\|290181\|31\|NC_003923\|CRT	290181-290211	31	NC_003923.1	1483529-1483559	0	1.0
NC_003923_2	2.2\|290181\|31\|NC_003923\|CRT	290181-290211	31	NC_003923.1	1992659-1992689	0	1.0
NC_003923_2	2.2\|290181\|31\|NC_003923\|CRT	290181-290211	31	NC_003923.1	2371826-2371856	0	1.0
NC_003923_2	2.3\|290236\|32\|NC_003923\|CRT	290236-290267	32	NC_003923.1	1142505-1142536	0	1.0
NC_003923_2	2.3\|290236\|32\|NC_003923\|CRT	290236-290267	32	NC_003923.1	1226473-1226504	0	1.0
NC_003923_2	2.3\|290236\|32\|NC_003923\|CRT	290236-290267	32	NC_003923.1	1226529-1226560	0	1.0
NC_003923_4	4.1\|813823\|29\|NC_003923\|CRISPRCasFinder	813823-813851	29	NC_003923.1	2776985-2777013	0	1.0
NC_003923_2	2.1\|290125\|32\|NC_003923\|CRT	290125-290156	32	NC_003923.1	1142505-1142536	1	0.969
NC_003923_2	2.1\|290125\|32\|NC_003923\|CRT	290125-290156	32	NC_003923.1	1226473-1226504	1	0.969
NC_003923_2	2.1\|290125\|32\|NC_003923\|CRT	290125-290156	32	NC_003923.1	1226529-1226560	1	0.969
NC_003923_2	2.2\|290181\|31\|NC_003923\|CRT	290181-290211	31	NC_003923.1	274915-274945	1	0.968
NC_003923_2	2.2\|290181\|31\|NC_003923\|CRT	290181-290211	31	NC_003923.1	944058-944088	1	0.968
NC_003923_2	2.2\|290181\|31\|NC_003923\|CRT	290181-290211	31	NC_003923.1	1483587-1483617	1	0.968
NC_003923_2	2.2\|290181\|31\|NC_003923\|CRT	290181-290211	31	NC_003923.1	1698510-1698540	1	0.968
NC_003923_2	2.2\|290181\|31\|NC_003923\|CRT	290181-290211	31	NC_003923.1	2611707-2611737	1	0.968
NC_003923_2	2.3\|290236\|32\|NC_003923\|CRT	290236-290267	32	NC_003923.1	1678836-1678867	1	0.969
NC_003923_2	2.3\|290236\|32\|NC_003923\|CRT	290236-290267	32	NC_003923.1	2776878-2776909	1	0.969
NC_003923_4	4.1\|813823\|29\|NC_003923\|CRISPRCasFinder	813823-813851	29	NC_003923.1	367908-367936	1	0.966
NC_003923_4	4.1\|813823\|29\|NC_003923\|CRISPRCasFinder	813823-813851	29	NC_003923.1	1226425-1226453	1	0.966
NC_003923_4	4.1\|813823\|29\|NC_003923\|CRISPRCasFinder	813823-813851	29	NC_003923.1	1483594-1483622	1	0.966
NC_003923_4	4.1\|813823\|29\|NC_003923\|CRISPRCasFinder	813823-813851	29	NC_003923.1	1841763-1841791	1	0.966
NC_003923_5	5.1\|875704\|34\|NC_003923\|CRISPRCasFinder	875704-875737	34	NC_003923.1	1440645-1440678	1	0.971
NC_003923_2	2.1\|290125\|32\|NC_003923\|CRT	290125-290156	32	NC_003923.1	1678836-1678867	2	0.938
NC_003923_2	2.1\|290125\|32\|NC_003923\|CRT	290125-290156	32	NC_003923.1	2776878-2776909	2	0.938
NC_003923_2	2.2\|290181\|31\|NC_003923\|CRT	290181-290211	31	NC_003923.1	819262-819292	2	0.935
NC_003923_2	2.2\|290181\|31\|NC_003923\|CRT	290181-290211	31	NC_003923.1	1142450-1142480	2	0.935
NC_003923_2	2.3\|290236\|32\|NC_003923\|CRT	290236-290267	32	NC_003923.1	1664307-1664338	2	0.938
NC_003923_4	4.1\|813823\|29\|NC_003923\|CRISPRCasFinder	813823-813851	29	NC_003923.1	166804-166832	2	0.931
NC_003923_4	4.1\|813823\|29\|NC_003923\|CRISPRCasFinder	813823-813851	29	NC_003923.1	274910-274938	2	0.931
NC_003923_4	4.1\|813823\|29\|NC_003923\|CRISPRCasFinder	813823-813851	29	NC_003923.1	819257-819285	2	0.931
NC_003923_4	4.1\|813823\|29\|NC_003923\|CRISPRCasFinder	813823-813851	29	NC_003923.1	875746-875774	2	0.931
NC_003923_4	4.1\|813823\|29\|NC_003923\|CRISPRCasFinder	813823-813851	29	NC_003923.1	924490-924518	2	0.931
NC_003923_4	4.1\|813823\|29\|NC_003923\|CRISPRCasFinder	813823-813851	29	NC_003923.1	1142457-1142485	2	0.931
NC_003923_4	4.1\|813823\|29\|NC_003923\|CRISPRCasFinder	813823-813851	29	NC_003923.1	1142568-1142596	2	0.931
NC_003923_4	4.1\|813823\|29\|NC_003923\|CRISPRCasFinder	813823-813851	29	NC_003923.1	1664245-1664273	2	0.931
NC_003923_10	10.1\|2337601\|26\|NC_003923\|CRISPRCasFinder	2337601-2337626	26	NC_003923.1	1142379-1142404	2	0.923

1. spacer 1.1|166843|33|NC_003923|CRISPRCasFinder matches to position: 1067886-1067918, mismatch: 0, identity: 1.0

tgggccccaacaaagagaaattggattcccaat	CRISPR spacer
tgggccccaacaaagagaaattggattcccaat	Protospacer
*********************************

2. spacer 1.1|166843|33|NC_003923|CRISPRCasFinder matches to position: 1440645-1440677, mismatch: 0, identity: 1.0

tgggccccaacaaagagaaattggattcccaat	CRISPR spacer
tgggccccaacaaagagaaattggattcccaat	Protospacer
*********************************

3. spacer 1.1|166843|33|NC_003923|CRISPRCasFinder matches to position: 1992728-1992760, mismatch: 0, identity: 1.0

tgggccccaacaaagagaaattggattcccaat	CRISPR spacer
tgggccccaacaaagagaaattggattcccaat	Protospacer
*********************************

4. spacer 2.2|290181|31|NC_003923|CRT matches to position: 141481-141511, mismatch: 0, identity: 1.0

cagagaatttcgaaaagaaattctacaggca	CRISPR spacer
cagagaatttcgaaaagaaattctacaggca	Protospacer
*******************************

5. spacer 2.2|290181|31|NC_003923|CRT matches to position: 166797-166827, mismatch: 0, identity: 1.0

cagagaatttcgaaaagaaattctacaggca	CRISPR spacer
cagagaatttcgaaaagaaattctacaggca	Protospacer
*******************************

6. spacer 2.2|290181|31|NC_003923|CRT matches to position: 819320-819350, mismatch: 0, identity: 1.0

cagagaatttcgaaaagaaattctacaggca	CRISPR spacer
cagagaatttcgaaaagaaattctacaggca	Protospacer
*******************************

7. spacer 2.2|290181|31|NC_003923|CRT matches to position: 875751-875781, mismatch: 0, identity: 1.0

cagagaatttcgaaaagaaattctacaggca	CRISPR spacer
cagagaatttcgaaaagaaattctacaggca	Protospacer
*******************************

8. spacer 2.2|290181|31|NC_003923|CRT matches to position: 924483-924513, mismatch: 0, identity: 1.0

cagagaatttcgaaaagaaattctacaggca	CRISPR spacer
cagagaatttcgaaaagaaattctacaggca	Protospacer
*******************************

9. spacer 2.2|290181|31|NC_003923|CRT matches to position: 1041765-1041795, mismatch: 0, identity: 1.0

cagagaatttcgaaaagaaattctacaggca	CRISPR spacer
cagagaatttcgaaaagaaattctacaggca	Protospacer
*******************************

10. spacer 2.2|290181|31|NC_003923|CRT matches to position: 1041881-1041911, mismatch: 0, identity: 1.0

cagagaatttcgaaaagaaattctacaggca	CRISPR spacer
cagagaatttcgaaaagaaattctacaggca	Protospacer
*******************************

11. spacer 2.2|290181|31|NC_003923|CRT matches to position: 1350827-1350857, mismatch: 0, identity: 1.0

cagagaatttcgaaaagaaattctacaggca	CRISPR spacer
cagagaatttcgaaaagaaattctacaggca	Protospacer
*******************************

12. spacer 2.2|290181|31|NC_003923|CRT matches to position: 1440751-1440781, mismatch: 0, identity: 1.0

cagagaatttcgaaaagaaattctacaggca	CRISPR spacer
cagagaatttcgaaaagaaattctacaggca	Protospacer
*******************************

13. spacer 2.2|290181|31|NC_003923|CRT matches to position: 1483471-1483501, mismatch: 0, identity: 1.0

cagagaatttcgaaaagaaattctacaggca	CRISPR spacer
cagagaatttcgaaaagaaattctacaggca	Protospacer
*******************************

14. spacer 2.2|290181|31|NC_003923|CRT matches to position: 1483529-1483559, mismatch: 0, identity: 1.0

cagagaatttcgaaaagaaattctacaggca	CRISPR spacer
cagagaatttcgaaaagaaattctacaggca	Protospacer
*******************************

15. spacer 2.2|290181|31|NC_003923|CRT matches to position: 1992659-1992689, mismatch: 0, identity: 1.0

cagagaatttcgaaaagaaattctacaggca	CRISPR spacer
cagagaatttcgaaaagaaattctacaggca	Protospacer
*******************************

16. spacer 2.2|290181|31|NC_003923|CRT matches to position: 2371826-2371856, mismatch: 0, identity: 1.0

cagagaatttcgaaaagaaattctacaggca	CRISPR spacer
cagagaatttcgaaaagaaattctacaggca	Protospacer
*******************************

17. spacer 2.3|290236|32|NC_003923|CRT matches to position: 1142505-1142536, mismatch: 0, identity: 1.0

tagaagctggcggaaagtcagcttacaataat	CRISPR spacer
tagaagctggcggaaagtcagcttacaataat	Protospacer
********************************

18. spacer 2.3|290236|32|NC_003923|CRT matches to position: 1226473-1226504, mismatch: 0, identity: 1.0

tagaagctggcggaaagtcagcttacaataat	CRISPR spacer
tagaagctggcggaaagtcagcttacaataat	Protospacer
********************************

19. spacer 2.3|290236|32|NC_003923|CRT matches to position: 1226529-1226560, mismatch: 0, identity: 1.0

tagaagctggcggaaagtcagcttacaataat	CRISPR spacer
tagaagctggcggaaagtcagcttacaataat	Protospacer
********************************

20. spacer 4.1|813823|29|NC_003923|CRISPRCasFinder matches to position: 2776985-2777013, mismatch: 0, identity: 1.0

tgcattgtttgtagaatttcttttcgaaa	CRISPR spacer
tgcattgtttgtagaatttcttttcgaaa	Protospacer
*****************************

21. spacer 2.1|290125|32|NC_003923|CRT matches to position: 1142505-1142536, mismatch: 1, identity: 0.969

tagaagctggcggaaagtcagcatacaataat	CRISPR spacer
tagaagctggcggaaagtcagcttacaataat	Protospacer
********************** *********

22. spacer 2.1|290125|32|NC_003923|CRT matches to position: 1226473-1226504, mismatch: 1, identity: 0.969

tagaagctggcggaaagtcagcatacaataat	CRISPR spacer
tagaagctggcggaaagtcagcttacaataat	Protospacer
********************** *********

23. spacer 2.1|290125|32|NC_003923|CRT matches to position: 1226529-1226560, mismatch: 1, identity: 0.969

tagaagctggcggaaagtcagcatacaataat	CRISPR spacer
tagaagctggcggaaagtcagcttacaataat	Protospacer
********************** *********

24. spacer 2.2|290181|31|NC_003923|CRT matches to position: 274915-274945, mismatch: 1, identity: 0.968

cagagaatttcgaaaagaaattctacaggca	CRISPR spacer
catagaatttcgaaaagaaattctacaggca	Protospacer
** ****************************

25. spacer 2.2|290181|31|NC_003923|CRT matches to position: 944058-944088, mismatch: 1, identity: 0.968

cagagaatttcgaaaagaaattctacaggca	CRISPR spacer
cagagaatttctaaaagaaattctacaggca	Protospacer
*********** *******************

26. spacer 2.2|290181|31|NC_003923|CRT matches to position: 1483587-1483617, mismatch: 1, identity: 0.968

cagagaatttcgaaaagaaattctacaggca	CRISPR spacer
cagagaatttcgaaaagaaattctacagaca	Protospacer
****************************.**

27. spacer 2.2|290181|31|NC_003923|CRT matches to position: 1698510-1698540, mismatch: 1, identity: 0.968

cagagaatttcgaaaagaaattctacaggca	CRISPR spacer
cagagaatttcgtaaagaaattctacaggca	Protospacer
************ ******************

28. spacer 2.2|290181|31|NC_003923|CRT matches to position: 2611707-2611737, mismatch: 1, identity: 0.968

cagagaatttcgaaaagaaattctacaggca	CRISPR spacer
cagagaatttcgaaatgaaattctacaggca	Protospacer
*************** ***************

29. spacer 2.3|290236|32|NC_003923|CRT matches to position: 1678836-1678867, mismatch: 1, identity: 0.969

tagaagctggcggaaagtcagcttacaataat	CRISPR spacer
tagaagctggcggaaagtcagcttacgataat	Protospacer
**************************.*****

30. spacer 2.3|290236|32|NC_003923|CRT matches to position: 2776878-2776909, mismatch: 1, identity: 0.969

tagaagctggcggaaagtcagcttacaataat	CRISPR spacer
tagaagctggcggaaagtcaggttacaataat	Protospacer
********************* **********

31. spacer 4.1|813823|29|NC_003923|CRISPRCasFinder matches to position: 367908-367936, mismatch: 1, identity: 0.966

tgcattgtttgtagaatttcttttcgaaa	CRISPR spacer
tgcattgcttgtagaatttcttttcgaaa	Protospacer
*******.*********************

32. spacer 4.1|813823|29|NC_003923|CRISPRCasFinder matches to position: 1226425-1226453, mismatch: 1, identity: 0.966

tgcattgtttgtagaatttcttttcgaaa	CRISPR spacer
tgcattgtctgtagaatttcttttcgaaa	Protospacer
********.********************

33. spacer 4.1|813823|29|NC_003923|CRISPRCasFinder matches to position: 1483594-1483622, mismatch: 1, identity: 0.966

tgcattgtttgtagaatttcttttcgaaa	CRISPR spacer
tgcattgtctgtagaatttcttttcgaaa	Protospacer
********.********************

34. spacer 4.1|813823|29|NC_003923|CRISPRCasFinder matches to position: 1841763-1841791, mismatch: 1, identity: 0.966

tgcattgtttgtagaatttcttttcgaaa	CRISPR spacer
tgcattgtctgtagaatttcttttcgaaa	Protospacer
********.********************

35. spacer 5.1|875704|34|NC_003923|CRISPRCasFinder matches to position: 1440645-1440678, mismatch: 1, identity: 0.971

attgagaatccaatttctctttgttggggcccat	CRISPR spacer
attgggaatccaatttctctttgttggggcccat	Protospacer
****.*****************************

36. spacer 2.1|290125|32|NC_003923|CRT matches to position: 1678836-1678867, mismatch: 2, identity: 0.938

tagaagctggcggaaagtcagcatacaataat	CRISPR spacer
tagaagctggcggaaagtcagcttacgataat	Protospacer
********************** ***.*****

37. spacer 2.1|290125|32|NC_003923|CRT matches to position: 2776878-2776909, mismatch: 2, identity: 0.938

tagaagctggcggaaagtcagcatacaataat	CRISPR spacer
tagaagctggcggaaagtcaggttacaataat	Protospacer
*********************  *********

38. spacer 2.2|290181|31|NC_003923|CRT matches to position: 819262-819292, mismatch: 2, identity: 0.935

cagagaatttcgaaaagaaattctacaggca	CRISPR spacer
cagagaatttcgaaaagaatttctacagaca	Protospacer
******************* ********.**

39. spacer 2.2|290181|31|NC_003923|CRT matches to position: 1142450-1142480, mismatch: 2, identity: 0.935

cagagaatttcgaaaagaaattctacaggca	CRISPR spacer
cagagaatttcaaaaagaaattctacagaca	Protospacer
***********.****************.**

40. spacer 2.3|290236|32|NC_003923|CRT matches to position: 1664307-1664338, mismatch: 2, identity: 0.938

tagaagctggcggaaagtcagcttacaataat	CRISPR spacer
tagaagctgacgaaaagtcagcttacaataat	Protospacer
*********.**.*******************

41. spacer 4.1|813823|29|NC_003923|CRISPRCasFinder matches to position: 166804-166832, mismatch: 2, identity: 0.931

tgcattgtttgtagaatttcttttcgaaa	CRISPR spacer
tgcattgcctgtagaatttcttttcgaaa	Protospacer
*******..********************

42. spacer 4.1|813823|29|NC_003923|CRISPRCasFinder matches to position: 274910-274938, mismatch: 2, identity: 0.931

tgcattgtttgtagaatttcttttcgaaa	CRISPR spacer
tgcattgcctgtagaatttcttttcgaaa	Protospacer
*******..********************

43. spacer 4.1|813823|29|NC_003923|CRISPRCasFinder matches to position: 819257-819285, mismatch: 2, identity: 0.931

tgcattgtttgtagaatttcttttcgaaa	CRISPR spacer
tgcattgtctgtagaaattcttttcgaaa	Protospacer
********.******* ************

44. spacer 4.1|813823|29|NC_003923|CRISPRCasFinder matches to position: 875746-875774, mismatch: 2, identity: 0.931

tgcattgtttgtagaatttcttttcgaaa	CRISPR spacer
tgcattgcctgtagaatttcttttcgaaa	Protospacer
*******..********************

45. spacer 4.1|813823|29|NC_003923|CRISPRCasFinder matches to position: 924490-924518, mismatch: 2, identity: 0.931

tgcattgtttgtagaatttcttttcgaaa	CRISPR spacer
tgcattgcctgtagaatttcttttcgaaa	Protospacer
*******..********************

46. spacer 4.1|813823|29|NC_003923|CRISPRCasFinder matches to position: 1142457-1142485, mismatch: 2, identity: 0.931

tgcattgtttgtagaatttcttttcgaaa	CRISPR spacer
tgcattgtctgtagaatttctttttgaaa	Protospacer
********.***************.****

47. spacer 4.1|813823|29|NC_003923|CRISPRCasFinder matches to position: 1142568-1142596, mismatch: 2, identity: 0.931

tgcattgtttgtagaatttcttttcgaaa	CRISPR spacer
tgcattgtctgtagaatttctttttgaaa	Protospacer
********.***************.****

48. spacer 4.1|813823|29|NC_003923|CRISPRCasFinder matches to position: 1664245-1664273, mismatch: 2, identity: 0.931

tgcattgtttgtagaatttcttttcgaaa	CRISPR spacer
tgcattgcctgtagaatttcttttcgaaa	Protospacer
*******..********************

49. spacer 10.1|2337601|26|NC_003923|CRISPRCasFinder matches to position: 1142379-1142404, mismatch: 2, identity: 0.923

tcgtcaccttctatgttggggccccg	CRISPR spacer
tcgtcagcttctgtgttggggccccg	Protospacer
****** *****.*************

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NC_003923_7	7.1\|1784433\|27\|NC_003923\|CRISPRCasFinder	1784433-1784459	27	KM359505	Prochlorococcus phage P-TIM68, complete genome	102710-102736	5	0.815
NC_003923_4	4.1\|813823\|29\|NC_003923\|CRISPRCasFinder	813823-813851	29	MN693281	Marine virus AFVG_25M371, complete genome	6448-6476	7	0.759
NC_003923_9	9.1\|2238413\|33\|NC_003923\|CRISPRCasFinder	2238413-2238445	33	JN882286	Cronobacter phage vB_CsaP_GAP52, complete genome	23035-23067	7	0.788
NC_003923_9	9.1\|2238413\|33\|NC_003923\|CRISPRCasFinder	2238413-2238445	33	CP030544	Staphylococcus aureus strain ER04166.3 plasmid unnamed2, complete sequence	7568-7600	7	0.788
NC_003923_2	2.1\|290125\|32\|NC_003923\|CRT	290125-290156	32	NZ_CP044300	Escherichia coli strain P59A plasmid pP59A-2, complete sequence	114277-114308	8	0.75
NC_003923_6	6.1\|1698564\|32\|NC_003923\|CRISPRCasFinder	1698564-1698595	32	MT889383	Mycobacterium phage MiniLon, complete genome	11248-11279	9	0.719
NC_003923_6	6.1\|1698564\|32\|NC_003923\|CRISPRCasFinder	1698564-1698595	32	KT281791	Mycobacterium phage Lolly9, complete genome	11248-11279	9	0.719

1. spacer 7.1|1784433|27|NC_003923|CRISPRCasFinder matches to KM359505 (Prochlorococcus phage P-TIM68, complete genome) position: , mismatch: 5, identity: 0.815

gaatttcgaaaagaaattctacagacc	CRISPR spacer
ctatttccaaaagaaattatacagatc	Protospacer
  ***** ********** ******.*

2. spacer 4.1|813823|29|NC_003923|CRISPRCasFinder matches to MN693281 (Marine virus AFVG_25M371, complete genome) position: , mismatch: 7, identity: 0.759

tgcattgtttgtagaatttcttttcgaaa	CRISPR spacer
tgcattgtttgtaggatttcttctaagtg	Protospacer
**************.*******.* .. .

3. spacer 9.1|2238413|33|NC_003923|CRISPRCasFinder matches to JN882286 (Cronobacter phage vB_CsaP_GAP52, complete genome) position: , mismatch: 7, identity: 0.788

ttgcatatctttagctttattgtttgcaactga	CRISPR spacer
ttgcatatctttagctttatagcttttatatgc	Protospacer
******************** *.** .*  **

4. spacer 9.1|2238413|33|NC_003923|CRISPRCasFinder matches to CP030544 (Staphylococcus aureus strain ER04166.3 plasmid unnamed2, complete sequence) position: , mismatch: 7, identity: 0.788

ttgcatatctttagctttattgtttgcaactga	CRISPR spacer
ttgaataactttagctttattgttataaacagt	Protospacer
*** *** ****************   *** *

5. spacer 2.1|290125|32|NC_003923|CRT matches to NZ_CP044300 (Escherichia coli strain P59A plasmid pP59A-2, complete sequence) position: , mismatch: 8, identity: 0.75

tagaagctggcggaaagtcagcatacaataat	CRISPR spacer
aagaagctggcggaacttcagcattagttaaa	Protospacer
 **************  *******  . ***

6. spacer 6.1|1698564|32|NC_003923|CRISPRCasFinder matches to MT889383 (Mycobacterium phage MiniLon, complete genome) position: , mismatch: 9, identity: 0.719

gcacattattgaaatctgacttttggtcagct	CRISPR spacer
accccttcttgaaatctgactttaggtcctga	Protospacer
.* * ** *************** ****

7. spacer 6.1|1698564|32|NC_003923|CRISPRCasFinder matches to KT281791 (Mycobacterium phage Lolly9, complete genome) position: , mismatch: 9, identity: 0.719

gcacattattgaaatctgacttttggtcagct	CRISPR spacer
accccttcttgaaatctgactttaggtcctga	Protospacer
.* * ** *************** ****

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

750912 : 758733

Hokovirus(16.67%)

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000244415.1\|750912_751968_-	two-component system sensor histidine kinase SaeS	A0A1V0SGX0	Hokovirus	3.6e-14	29.8
WP_000149344.1\|751967_752654_-	response regulator transcription factor	NA	NA	NA	NA
WP_001037807.1\|752628_753102_-	DoxX family protein	NA	NA	NA	NA
WP_001093562.1\|753444_753885_-	DM13 domain-containing protein	NA	NA	NA	NA
WP_000604990.1\|754164_754749_-	hypothetical protein	NA	NA	NA	NA
WP_001062972.1\|754847_755561_-	7-carboxy-7-deazaguanine synthase QueE	A0A1U9WRB6	Streptococcus_virus	6.5e-52	43.5
WP_000941336.1\|755564_755984_-	6-carboxytetrahydropterin synthase QueD	S4U060	uncultured_phage	6.3e-07	28.7
WP_000446724.1\|755985_756654_-	7-cyano-7-deazaguanine synthase QueC	A0A2H4J8Q7	uncultured_Caudovirales_phage	9.6e-66	57.5
WP_000604515.1\|757004_757598_+	aminodeoxychorismate/anthranilate synthase component II	A0A0P0IKJ1	Acinetobacter_phage	1.2e-38	43.5
WP_001217797.1\|757581_758733_+	anthranilate synthase component I family protein	S4VNU7	Pandoravirus	2.1e-23	36.1

DBSCAN-SWA_2

770705 : 785436

uncultured_Caudovirales_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000663032.1\|770705_771764_+	histidinol-phosphate transaminase	A0A1X6WGT4	Pacmanvirus	1.8e-21	26.7
WP_000197271.1\|772058_772601_+	5'-3'-deoxyribonucleotidase	NA	NA	NA	NA
WP_000429008.1\|773281_774199_-	diacylglycerol kinase family lipid kinase	A0A1V0SBJ0	Catovirus	2.8e-07	22.4
WP_031760357.1\|774288_774390_+	hypothetical protein	NA	NA	NA	NA
WP_000193751.1\|774467_775973_-	peptide MFS transporter	A0A0P0IY73	Acinetobacter_phage	2.0e-58	32.2
WP_000930014.1\|776313_776814_-	NADPH-dependent 7-cyano-7-deazaguanine reductase QueF	E7DN65	Pneumococcus_phage	5.9e-52	71.5
WP_001068497.1\|776833_777700_-	DMT family transporter	NA	NA	NA	NA
WP_000692521.1\|778500_778899_+	class Ib ribonucleoside-diphosphate reductase assembly flavoprotein NrdI	A0A2H4J545	uncultured_Caudovirales_phage	1.2e-52	72.0
WP_000855505.1\|778861_780967_+	class 1b ribonucleoside-diphosphate reductase subunit alpha	A0A2H4J2N6	uncultured_Caudovirales_phage	0.0e+00	91.7
WP_000562498.1\|781084_782056_+	class 1b ribonucleoside-diphosphate reductase subunit beta	A0A2H4J4P3	uncultured_Caudovirales_phage	4.2e-171	91.3
WP_000499195.1\|782569_782725_+	hypothetical protein	NA	NA	NA	NA
WP_000876318.1\|782763_783735_+	ABC transporter permease	A0A2H4IY97	uncultured_Caudovirales_phage	4.3e-139	78.9
WP_001245573.1\|783721_784678_+	iron chelate uptake ABC transporter family permease subunit	A0A2H4J116	uncultured_Caudovirales_phage	1.2e-05	57.8
WP_000616840.1\|784674_785436_+	ABC transporter ATP-binding protein	Q9EMR9	Amsacta_moorei_entomopoxvirus	6.5e-18	31.6

DBSCAN-SWA_3

836063 : 853484

Staphylococcus_phage(57.14%)

capsid,integrase,terminase

attL 838723:838740|attR 851670:851687

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_001050053.1\|836063_838436_+	ribonuclease R	Q0GXV6	Lactococcus_phage	2.3e-93	38.9
WP_001085185.1\|838457_838922_+	SsrA-binding protein SmpB	W5RAM5	Staphylococcus_phage	1.5e-81	100.0
838723:838740	attL	NA	NA	NA	NA
WP_000586155.1\|839477_839693_-	hypothetical protein	NA	NA	NA	NA
WP_025174195.1\|839704_840811_-\|integrase	site-specific integrase	A0A1B2AQ00	Phage_Wrath	2.0e-76	43.0
WP_000583241.1\|840825_841563_-	helix-turn-helix transcriptional regulator	A0A1W6JQE6	Staphylococcus_phage	1.2e-05	31.2
WP_000163543.1\|841714_841933_+	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_000773732.1\|841944_842091_+	hypothetical protein	NA	NA	NA	NA
WP_001058500.1\|842083_842308_+	hypothetical protein	A0A1W6JPA6	Staphylococcus_phage	2.9e-14	60.3
WP_001103961.1\|842308_842608_+	DUF1474 family protein	Q4ZE75	Staphylococcus_phage	5.9e-31	66.7
WP_000985236.1\|842699_845072_+	primase	A0A2H4JCU9	uncultured_Caudovirales_phage	2.7e-147	41.2
WP_001081425.1\|845744_846089_+	hypothetical protein	A0A1W6JQD5	Staphylococcus_phage	2.7e-40	65.2
WP_000884055.1\|846313_846520_+	hypothetical protein	NA	NA	NA	NA
WP_000657544.1\|846506_847565_+\|capsid	phage capsid protein	A0A0K2CZ99	Paenibacillus_phage	3.6e-14	26.6
WP_000253086.1\|847746_848238_+	hypothetical protein	A0A2H4JB26	uncultured_Caudovirales_phage	7.9e-25	41.1
WP_100292232.1\|848234_848390_+\|terminase	terminase	A0A1W6JQF0	Staphylococcus_phage	5.3e-20	94.0
WP_000122406.1\|848598_849576_+	DUF4868 domain-containing protein	NA	NA	NA	NA
WP_000499373.1\|849591_850152_+	hypothetical protein	NA	NA	NA	NA
WP_001035625.1\|850451_851006_-	DUF4888 domain-containing protein	A0A1W6JQE5	Staphylococcus_phage	5.2e-73	76.1
WP_001043551.1\|851794_852595_+	staphylococcal enterotoxin type C2	A0A097PAT7	Streptococcus_pyogenes_phage	8.0e-51	43.8
851670:851687	attR	NA	NA	NA	NA
WP_000746597.1\|852761_853484_-	staphylococcal enterotoxin type L	A0A1X9H080	Staphylococcus_phage	1.6e-26	34.9

DBSCAN-SWA_4

1043245 : 1051718

Synechococcus_phage(33.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000861572.1\|1043245_1043728_+	5-(carboxyamino)imidazole ribonucleotide mutase	A0A2P0VNU7	Tetraselmis_virus	6.2e-22	44.7
WP_000009495.1\|1043714_1044839_+	5-(carboxyamino)imidazole ribonucleotide synthase	NA	NA	NA	NA
WP_000174053.1\|1044842_1045547_+	phosphoribosylaminoimidazolesuccinocarboxamide synthase	M4R1E8	Synechococcus_phage	7.3e-48	42.1
WP_000848350.1\|1045546_1045810_+	phosphoribosylformylglycinamidine synthase subunit PurS	NA	NA	NA	NA
WP_000666799.1\|1045811_1046483_+	phosphoribosylformylglycinamidine synthase I	NA	NA	NA	NA
WP_000032727.1\|1046475_1048665_+	phosphoribosylformylglycinamidine synthase subunit PurL	A6N228	Microbacterium_phage	1.0e-140	39.7
WP_000483713.1\|1048643_1050128_+	amidophosphoribosyltransferase	A0A0M3SGR2	Mollivirus	3.2e-45	31.7
WP_000030823.1\|1050120_1051149_+	phosphoribosylformylglycinamidine cyclo-ligase	Q58MH8	Prochlorococcus_phage	1.3e-61	41.4
WP_000238663.1\|1051151_1051718_+	phosphoribosylglycinamide formyltransferase	M4QRX9	Synechococcus_phage	1.0e-28	40.1

DBSCAN-SWA_5

1493286 : 1574930

Staphylococcus_phage(82.67%)

plate,capsid,protease,head,portal,tRNA,tail,holin,integrase,terminase

attL 1533674:1533691|attR 1579138:1579155

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000858792.1\|1493286_1494579_-\|tRNA	asparagine--tRNA ligase	M1PB22	Moumouvirus	1.9e-54	31.1
WP_000525081.1\|1494900_1497594_-	ATP-dependent helicase DinG	A0A1X9I5C8	Streptococcus_phage	8.2e-47	34.4
WP_000049923.1\|1497617_1498589_-	biotin--[acetyl-CoA-carboxylase] ligase	NA	NA	NA	NA
WP_000361543.1\|1498575_1499778_-\|tRNA	CCA tRNA nucleotidyltransferase	H7BUW3	unidentified_phage	3.2e-35	42.5
WP_000690035.1\|1499782_1500925_-	N-acetyl-alpha-D-glucosaminyl L-malate synthase BshA	NA	NA	NA	NA
WP_000839926.1\|1501166_1501484_-	nucleotide pyrophosphohydrolase	NA	NA	NA	NA
WP_031774998.1\|1501819_1502500_-	zinc metallopeptidase	NA	NA	NA	NA
WP_000154680.1\|1502571_1503159_-	DUF1405 domain-containing protein	NA	NA	NA	NA
WP_000005212.1\|1503148_1503724_-	YpiB family protein	G3MAV7	Bacillus_virus	2.1e-08	27.2
WP_000389510.1\|1503737_1504982_-	hypothetical protein	NA	NA	NA	NA
WP_000245895.1\|1504988_1506287_-	3-phosphoshikimate 1-carboxyvinyltransferase	NA	NA	NA	NA
WP_000776341.1\|1506296_1507361_-	3-dehydroquinate synthase	NA	NA	NA	NA
WP_001269923.1\|1507386_1508553_-	chorismate synthase	A0A291AU41	Pandoravirus	2.0e-34	32.1
WP_000789519.1\|1508939_1509140_-	hypothetical protein	NA	NA	NA	NA
WP_000442479.1\|1509349_1509799_-	nucleoside-diphosphate kinase	D2E8E1	Anguillid_herpesvirus	8.3e-29	44.5
WP_001096470.1\|1509890_1510850_-	polyprenyl synthetase family protein	A0A1V0SE37	Indivirus	1.3e-10	24.4
WP_000774684.1\|1510851_1511577_-	demethylmenaquinone methyltransferase	NA	NA	NA	NA
WP_000450555.1\|1511579_1512152_-	heptaprenyl diphosphate synthase component 1	NA	NA	NA	NA
WP_001043863.1\|1512582_1512855_-	HU family DNA-binding protein	A7KV42	Bacillus_phage	4.2e-28	73.3
WP_000161738.1\|1513025_1514024_-	NAD(P)H-dependent glycerol-3-phosphate dehydrogenase	NA	NA	NA	NA
WP_000165530.1\|1514040_1515351_-	ribosome biogenesis GTPase Der	NA	NA	NA	NA
WP_000133954.1\|1515572_1516748_-	30S ribosomal protein S1	NA	NA	NA	NA
WP_000644391.1\|1517445_1518105_-	(d)CMP kinase	NA	NA	NA	NA
WP_000681769.1\|1518181_1519150_+	asparaginase	NA	NA	NA	NA
WP_001174260.1\|1519264_1520251_-	YpdA family putative bacillithiol disulfide reductase	NA	NA	NA	NA
WP_031867547.1\|1520411_1520528_-	hypothetical protein	NA	NA	NA	NA
WP_000069296.1\|1520652_1522113_-	elastin-binding protein EbpS	NA	NA	NA	NA
WP_000902120.1\|1522265_1523645_-	ATP-dependent DNA helicase RecQ	L7RCS0	Acanthamoeba_polyphaga_moumouvirus	2.9e-56	33.6
WP_001163801.1\|1523634_1524588_-	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_001151997.1\|1524695_1524944_+	ferredoxin	A0A127AYY7	Bacillus_phage	8.3e-15	48.0
WP_001186912.1\|1525049_1525595_-	ECF transporter S component	NA	NA	NA	NA
WP_000476340.1\|1526004_1526919_-	DUF1672 domain-containing protein	NA	NA	NA	NA
WP_000476881.1\|1526975_1527893_-	DUF1672 domain-containing protein	NA	NA	NA	NA
WP_000476866.1\|1527950_1528856_-	DUF1672 domain-containing protein	NA	NA	NA	NA
WP_000470336.1\|1528946_1529132_-	hypothetical protein	A0ZS61	Staphylococcus_virus	1.7e-25	100.0
WP_024937002.1\|1529380_1530364_-	Panton-Valentine bi-component leukocidin subunit F	A0A2I6PEU3	Staphylococcus_phage	4.0e-185	100.0
WP_000239545.1\|1530359_1531298_-	Panton-Valentine bi-component leukocidin subunit S	A0A2I6PER8	Staphylococcus_phage	3.7e-180	100.0
WP_000909207.1\|1531687_1533142_-	N-acetylmuramoyl-L-alanine amidase	M1TB12	Staphylococcus_phage	3.4e-289	100.0
WP_000339141.1\|1533152_1533455_-\|holin	phage holin	A0A2I6PF56	Staphylococcus_phage	3.1e-48	100.0
WP_000466784.1\|1533590_1533890_-	DUF2951 domain-containing protein	A0A2I6PER2	Staphylococcus_phage	2.0e-31	100.0
1533674:1533691	attL	NA	NA	NA	NA
WP_000916020.1\|1533935_1534100_-	XkdX family protein	A0A2I6PES4	Staphylococcus_phage	4.9e-24	100.0
WP_001166599.1\|1534092_1534482_-	DUF2977 domain-containing protein	A0A2I6PER1	Staphylococcus_phage	2.2e-62	100.0
WP_000067140.1\|1534481_1535948_-\|plate	phage baseplate upper protein	A7TWK6	Staphylococcus_phage	7.6e-257	100.0
WP_000429551.1\|1535947_1537858_-	minor structural protein	A0A2I6PF35	Staphylococcus_phage	0.0e+00	100.0
WP_000179858.1\|1537873_1538164_-	hypothetical protein	U5U457	Staphylococcus_phage	2.1e-49	100.0
WP_000384474.1\|1538163_1539747_-\|tail	phage tail protein	A0A2I6PEQ5	Staphylococcus_phage	9.3e-309	100.0
WP_001190533.1\|1539755_1540580_-\|tail	phage tail family protein	A0A2I6PER3	Staphylococcus_phage	4.1e-159	100.0
WP_001003441.1\|1540579_1546780_-\|tail	phage tail tape measure protein	A0A2I6PF36	Staphylococcus_phage	0.0e+00	99.5
WP_000438833.1\|1546793_1546952_-	hypothetical protein	A0A2I6PES8	Staphylococcus_phage	1.2e-19	100.0
WP_000589166.1\|1547002_1547344_-	hypothetical protein	A0A2I6PEQ2	Staphylococcus_phage	1.5e-54	100.0
WP_000169128.1\|1547401_1547857_-	Ig domain-containing protein	A0A2I6PF45	Staphylococcus_phage	1.3e-77	100.0
WP_000807536.1\|1547948_1548590_-\|tail	tail protein	A0A2I6PEP6	Staphylococcus_phage	5.9e-121	100.0
WP_001023806.1\|1548624_1549020_-	DUF3168 domain-containing protein	A0A2I6PEQ4	Staphylococcus_phage	8.8e-67	100.0
WP_000110023.1\|1549020_1549422_-	hypothetical protein	A0A2I6PF54	Staphylococcus_phage	8.1e-68	100.0
WP_000395498.1\|1549418_1549751_-	hypothetical protein	A0A2I6PES3	Staphylococcus_phage	4.1e-57	100.0
WP_000050973.1\|1549762_1550041_-\|head,tail	phage gp6-like head-tail connector protein	A0A2I6PEQ1	Staphylococcus_phage	2.1e-46	100.0
WP_001142734.1\|1550109_1551273_-\|capsid	phage major capsid protein	A0A2I6PEQ3	Staphylococcus_phage	1.2e-217	100.0
WP_000061866.1\|1551284_1552058_-\|protease	Clp protease ClpP	A0A2I6PEQ7	Staphylococcus_phage	2.4e-137	100.0
WP_001100665.1\|1552041_1553280_-\|portal	phage portal protein	A0A2I6PF26	Staphylococcus_phage	1.2e-234	100.0
WP_000153544.1\|1553284_1554976_-\|terminase	terminase large subunit	Q4ZD20	Staphylococcus_virus	0.0e+00	100.0
WP_000778933.1\|1554965_1555271_-\|terminase	P27 family phage terminase small subunit	A0A2I6PEQ6	Staphylococcus_phage	2.9e-49	100.0
WP_000160692.1\|1555398_1555713_-	HNH endonuclease	A0A2I6PF37	Staphylococcus_phage	4.2e-56	99.0
WP_000528512.1\|1555869_1556307_-	transcriptional regulator	A0A2I6PEN3	Staphylococcus_phage	7.9e-77	100.0
WP_001793488.1\|1556319_1557687_-	DEAD/DEAH box helicase	A0A2I6PE95	Staphylococcus_phage	1.7e-263	100.0
WP_001548892.1\|1557667_1557958_-	VRR-NUC domain-containing protein	A0A2I6PE31	Staphylococcus_phage	6.5e-51	100.0
WP_001801650.1\|1558091_1558190_+	hypothetical protein	A0A2I6PDP6	Staphylococcus_phage	3.7e-11	100.0
WP_000884870.1\|1558298_1560746_-	virulence-associated E family protein	A0A2I6PEP4	Staphylococcus_phage	0.0e+00	100.0
WP_000265252.1\|1561033_1561234_-	DUF1514 family protein	A0A2I6PEP5	Staphylococcus_phage	4.9e-26	100.0
WP_000237867.1\|1561301_1561454_-	transcriptional activator RinB	A0A2I6PEM5	Staphylococcus_phage	4.4e-19	96.0
WP_001125015.1\|1561456_1561657_-	hypothetical protein	A0A2I6PF22	Staphylococcus_phage	1.8e-28	100.0
WP_000195817.1\|1561631_1561820_-	DUF1381 domain-containing protein	A0A2H4PQK3	Staphylococcus_phage	1.8e-25	100.0
WP_001282074.1\|1561816_1562062_-	hypothetical protein	A0A2I6PDW7	Staphylococcus_phage	5.0e-36	100.0
WP_001061841.1\|1562098_1562632_-	dUTP diphosphatase	A0A2H4PQJ1	Staphylococcus_phage	2.1e-95	100.0
WP_000889679.1\|1562646_1562808_-	hypothetical protein	A0A2H4PQJ5	Staphylococcus_phage	4.9e-24	100.0
WP_000454993.1\|1562808_1563090_-	hypothetical protein	A0A2I6PCT3	Staphylococcus_phage	1.4e-47	100.0
WP_000028424.1\|1563090_1563264_-	hypothetical protein	A0A2H4PQJ2	Staphylococcus_phage	1.8e-24	100.0
WP_001826875.1\|1563253_1563505_-	DUF1024 family protein	A0A2H4PQK1	Staphylococcus_phage	8.4e-39	100.0
WP_000132192.1\|1563519_1563762_-	hypothetical protein	A0A2D1G5G2	Staphylococcus_phage	5.6e-40	98.8
WP_000235322.1\|1563776_1563977_-	hypothetical protein	A0A2I6PEM3	Staphylococcus_phage	4.3e-30	98.5
WP_000022728.1\|1563979_1564237_-	DUF3310 domain-containing protein	A0A2I6PEN5	Staphylococcus_phage	2.6e-43	100.0
WP_000113974.1\|1564236_1564638_-	PVL family protein	A0A2I6PEL5	Staphylococcus_phage	1.2e-68	100.0
WP_001164629.1\|1564637_1564823_-	DUF3113 family protein	A0A2I6PEM8	Staphylococcus_phage	7.0e-27	100.0
WP_001801657.1\|1564835_1566788_-	DNA polymerase	A0A2I6PEL4	Staphylococcus_phage	0.0e+00	100.0
WP_000645048.1\|1566855_1567413_-	DUF2815 family protein	A0A2I6PEP8	Staphylococcus_phage	1.8e-97	100.0
WP_000762552.1\|1567438_1568605_-	DUF2800 domain-containing protein	A0A2I6PEL9	Staphylococcus_phage	1.4e-221	100.0
WP_000985979.1\|1568601_1568964_-	hypothetical protein	A0A2I6PEM7	Staphylococcus_phage	3.7e-56	100.0
WP_000174994.1\|1568978_1569302_-	hypothetical protein	A0A2I6PF12	Staphylococcus_phage	5.9e-53	100.0
WP_001285963.1\|1569380_1569542_-	DUF1270 family protein	A0A2I6PEZ9	Staphylococcus_phage	5.0e-21	100.0
WP_001124190.1\|1569554_1569818_-	helix-turn-helix domain-containing protein	A0A2I6PDM6	Staphylococcus_phage	1.1e-44	100.0
WP_001036302.1\|1569842_1570058_-	hypothetical protein	A0A2I6PDN5	Staphylococcus_phage	1.3e-32	100.0
WP_001128433.1\|1570112_1570478_+	hypothetical protein	A0A2I6PF07	Staphylococcus_phage	2.4e-63	100.0
WP_001025401.1\|1570446_1570692_-	DUF2829 domain-containing protein	A0A2I6PF15	Staphylococcus_phage	5.1e-41	100.0
WP_000272860.1\|1570707_1570956_-	helix-turn-helix transcriptional regulator	A0A2I6PED6	Staphylococcus_phage	4.8e-39	98.8
WP_001260485.1\|1571119_1571443_+	helix-turn-helix transcriptional regulator	R4WAK9	Staphylococcus_phage	4.5e-53	99.1
WP_000525002.1\|1571455_1571917_+	hypothetical protein	A0A0H3U308	Staphylococcus_phage	4.3e-81	97.4
WP_000755718.1\|1571934_1572369_+	hypothetical protein	A0A2I6PEM0	Staphylococcus_phage	1.2e-24	100.0
WP_000449653.1\|1572397_1572793_+	hypothetical protein	A0A2I6PEJ7	Staphylococcus_phage	1.4e-69	99.2
WP_001166482.1\|1572991_1573615_-	hypothetical protein	B7T0F3	Staphylococcus_virus	9.8e-105	99.5
WP_000264191.1\|1573724_1574930_+\|integrase	site-specific integrase	M1RZA8	Staphylococcus_phage	1.0e-222	100.0
1579138:1579155	attR	NA	NA	NA	NA

DBSCAN-SWA_6

1635790 : 1644120

Staphylococcus_phage(16.67%)

tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_001213908.1\|1635790_1636576_-	metal ABC transporter ATP-binding protein	A0A2H4PQG7	Staphylococcus_phage	8.0e-19	28.3
WP_000924220.1\|1636701_1637592_-	deoxyribonuclease IV	A0A2H4UU70	Bodo_saltans_virus	3.4e-26	36.0
WP_001062177.1\|1637601_1638948_-	DEAD/DEAH box helicase	A0A1V0SIR5	Klosneuvirus	2.4e-55	34.0
WP_000683932.1\|1639061_1640162_-	Nif3-like dinuclear metal center hexameric protein	A0A1S5V250	Saudi_moumouvirus	5.2e-08	29.6
WP_000624585.1\|1640164_1640842_-\|tRNA	tRNA (adenine-N(1))-methyltransferase	NA	NA	NA	NA
WP_001283055.1\|1640972_1642079_-	RNA polymerase sigma factor RpoD	A0A2I7SAT0	Vibrio_phage	1.1e-37	38.1
WP_001217235.1\|1642302_1644120_-	DNA primase	A0A0K1LMQ9	Caulobacter_phage	7.9e-54	36.0

DBSCAN-SWA_7

1713729 : 1722772

uncultured_Mediterranean_phage(50.0%)

tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000364542.1\|1713729_1714248_-	adenine phosphoribosyltransferase	A0A1V0SKE5	Klosneuvirus	5.6e-29	46.5
WP_000594997.1\|1714269_1716543_-	single-stranded-DNA-specific exonuclease RecJ	A7KV88	Bacillus_phage	3.1e-63	29.1
WP_000749795.1\|1716745_1719025_-	protein translocase subunit SecDF	A0A1B1IVP7	uncultured_Mediterranean_phage	1.8e-31	35.8
WP_001160682.1\|1719299_1719560_-	preprotein translocase subunit YajC	A0A1B1IVR5	uncultured_Mediterranean_phage	8.2e-05	35.3
WP_001112045.1\|1719578_1720718_-\|tRNA	tRNA guanosine(34) transglycosylase Tgt	A0A1B1IVQ4	uncultured_Mediterranean_phage	5.4e-85	44.7
WP_001019178.1\|1720740_1721766_-\|tRNA	tRNA preQ1(34) S-adenosylmethionine ribosyltransferase-isomerase QueA	NA	NA	NA	NA
WP_001005768.1\|1721767_1722772_-	Holliday junction branch migration DNA helicase RuvB	B3GAM6	uncultured_virus	1.7e-05	29.1

DBSCAN-SWA_8

1846760 : 1922552

Staphylococcus_phage(94.64%)

protease,transposase,tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_001050541.1\|1846760_1853321_-	LPXTG-anchored repetitive surface protein SasC	A0A2H4PQU6	Staphylococcus_phage	5.9e-301	96.8
WP_000836465.1\|1853646_1853958_-	rhodanese-like domain-containing protein	A0A2H4PQR9	Staphylococcus_phage	1.6e-52	100.0
WP_001789004.1\|1853979_1856403_-\|tRNA	leucine--tRNA ligase	A0A2H4PQS0	Staphylococcus_phage	0.0e+00	99.7
WP_001025071.1\|1856690_1857872_-	MFS transporter	A0A2H4PQR6	Staphylococcus_phage	6.2e-217	99.7
WP_000526539.1\|1857981_1858935_+	TIGR01212 family radical SAM protein	A0A2H4PQV5	Staphylococcus_phage	2.2e-79	100.0
WP_000764419.1\|1858931_1859495_+	class I SAM-dependent methyltransferase	A0A2H4PQV0	Staphylococcus_phage	8.3e-103	99.5
WP_000757543.1\|1859614_1860016_-	MarR family transcriptional regulator	NA	NA	NA	NA
WP_000266096.1\|1860589_1861417_-	alpha/beta hydrolase	NA	NA	NA	NA
WP_001790712.1\|1861419_1861539_-	hypothetical protein	NA	NA	NA	NA
WP_001196354.1\|1861650_1862652_+	proline dehydrogenase	A0A2H4PQT6	Staphylococcus_phage	9.0e-185	99.7
WP_001008549.1\|1862773_1863238_-	6,7-dimethyl-8-ribityllumazine synthase	A0A2H4PQS3	Staphylococcus_phage	4.5e-70	100.0
WP_001159035.1\|1863250_1864432_-	3,4-dihydroxy-2-butanone-4-phosphate synthase	A0A2H4PQS2	Staphylococcus_phage	1.7e-227	100.0
WP_000493886.1\|1864442_1865075_-	riboflavin synthase	A0A2H4PQS5	Staphylococcus_phage	6.4e-112	99.0
WP_000077351.1\|1865081_1866125_-	bifunctional diaminohydroxyphosphoribosylaminopyrimidine deaminase/5-amino-6-(5-phosphoribosylamino)uracil reductase RibD	A0A2H4PQS8	Staphylococcus_phage	1.7e-197	99.7
WP_001261671.1\|1866605_1868108_-	FAD/NAD(P)-binding protein	A0A2H4PQX2	Staphylococcus_phage	1.5e-29	98.6
WP_000221179.1\|1868630_1868945_+	winged helix-turn-helix transcriptional regulator	A0A2H4PQT4	Staphylococcus_phage	2.0e-53	100.0
WP_000989116.1\|1868944_1870237_+	arsenite efflux transporter membrane subunit ArsB	A0A2H4PQU3	Staphylococcus_phage	1.1e-227	99.8
WP_001032833.1\|1870323_1871178_-	glucosaminidase domain-containing protein	Q4ZCC7	Staphylococcus_virus	9.8e-39	38.6
WP_000384171.1\|1871453_1871678_-	hypothetical protein	NA	NA	NA	NA
WP_000671052.1\|1871876_1872347_+	RNA polymerase sigma factor	A0A2H4PQT5	Staphylococcus_phage	1.0e-82	99.4
WP_001153742.1\|1872459_1872903_+	competence protein ComK	NA	NA	NA	NA
WP_001030469.1\|1872889_1873333_-	hypothetical protein	A0A2H4PQT8	Staphylococcus_phage	2.4e-57	98.6
WP_001168907.1\|1873628_1874264_+\|protease	CPBP family intramembrane metalloprotease SdpA	NA	NA	NA	NA
WP_001096494.1\|1874703_1875417_-	transaldolase	M1PR54	Cyanophage	5.5e-19	35.3
WP_000091445.1\|1875676_1875979_+	hypothetical protein	NA	NA	NA	NA
WP_001200542.1\|1876234_1876600_+	fluoride efflux transporter CrcB	A0A2H4PQR0	Staphylococcus_phage	3.6e-59	100.0
WP_000623476.1\|1876596_1876950_+	CrcB family protein	A0A2H4PQQ7	Staphylococcus_phage	2.0e-22	98.3
WP_000453314.1\|1877332_1878166_-	aldo/keto reductase	A0A2H4PQR8	Staphylococcus_phage	5.4e-159	100.0
WP_000366158.1\|1878377_1879286_-	NERD domain-containing protein	A0A2H4PQQ8	Staphylococcus_phage	1.7e-137	99.0
WP_000933822.1\|1879410_1880604_-	methionine adenosyltransferase	A0A2H4PQS6	Staphylococcus_phage	1.9e-218	99.7
WP_000109910.1\|1880975_1882568_+	phosphoenolpyruvate carboxykinase (ATP)	A0A2H4PQN1	Staphylococcus_phage	0.0e+00	99.8
WP_016169057.1\|1882945_1883692_-	S9 family peptidase	A0A2H4PQM6	Staphylococcus_phage	2.2e-143	99.2
WP_000672013.1\|1883696_1884170_-	nucleoside triphosphatase YtkD	A0A2H4PQM4	Staphylococcus_phage	7.2e-84	98.7
WP_000718107.1\|1884235_1884493_+	membrane protein insertion efficiency factor YidD	A0A2H4PQM5	Staphylococcus_phage	7.2e-46	100.0
WP_000778532.1\|1884489_1885491_-	o-succinylbenzoate synthase	A0A2H4PQM0	Staphylococcus_phage	2.8e-186	97.9
WP_000348356.1\|1885495_1886974_-	o-succinylbenzoate--CoA ligase	A0A2H4PQM9	Staphylococcus_phage	2.6e-281	97.0
WP_072419835.1\|1887132_1887588_-	DUF4909 domain-containing protein	A0A2H4PQN7	Staphylococcus_phage	5.7e-78	97.3
WP_001793444.1\|1887890_1888541_+	excalibur calcium-binding domain-containing protein	A0A2H4PQM8	Staphylococcus_phage	3.0e-56	99.1
WP_000070649.1\|1888621_1889617_+	DUF4352 domain-containing protein	A0A2H4PQN2	Staphylococcus_phage	4.2e-73	97.2
WP_000669017.1\|1889690_1890317_+	hypothetical protein	A0A2H4PQM7	Staphylococcus_phage	3.6e-91	94.7
WP_000627541.1\|1890357_1890699_+	DUF3969 family protein	A0A2H4PQN6	Staphylococcus_phage	8.1e-53	92.0
WP_000414202.1\|1890799_1891372_+	hypothetical protein	A0A2H4PQN4	Staphylococcus_phage	3.3e-22	89.7
WP_000375477.1\|1892500_1892677_-	hypothetical protein	NA	NA	NA	NA
WP_000070811.1\|1892687_1893071_-	hypothetical protein	NA	NA	NA	NA
WP_001549059.1\|1893674_1893818_-\|transposase	transposase	A0A2H4PQU1	Staphylococcus_phage	6.4e-20	100.0
WP_001801861.1\|1894020_1894116_+	type I toxin-antitoxin system Fst family toxin PepA1	NA	NA	NA	NA
WP_001791893.1\|1894238_1894340_+	hypothetical protein	NA	NA	NA	NA
WP_001037045.1\|1894687_1895065_-	DUF1433 domain-containing protein	NA	NA	NA	NA
WP_000831218.1\|1895585_1899698_-	ATP-binding protein	A0A2H4PQT3	Staphylococcus_phage	0.0e+00	100.0
WP_000072623.1\|1900547_1901747_-	restriction endonuclease subunit S	A0A2H4PQP5	Staphylococcus_phage	1.6e-228	99.7
WP_000028669.1\|1901739_1903296_-	type I restriction-modification system subunit M	A0A2H4PQP4	Staphylococcus_phage	1.6e-289	100.0
WP_001791797.1\|1903459_1903594_-	hypothetical protein	NA	NA	NA	NA
WP_001038709.1\|1903658_1904378_-\|protease	serine protease SplF	A0A2H4PQP1	Staphylococcus_phage	9.2e-131	99.2
WP_001038865.1\|1904498_1905218_-\|protease	serine protease SplC	A0A2H4PQP7	Staphylococcus_phage	1.1e-131	100.0
WP_001039444.1\|1905275_1905998_-\|protease	serine protease SplB	A0A2H4PQN0	Staphylococcus_phage	6.4e-132	100.0
WP_001005059.1\|1906122_1906830_-\|protease	serine protease SplA	A0A2H4PQN3	Staphylococcus_phage	7.7e-130	99.6
WP_001092763.1\|1907793_1908360_+	DUF4888 domain-containing protein	A0A2H4PQH6	Staphylococcus_phage	3.3e-99	100.0
WP_000586140.1\|1908833_1909532_-	hypothetical protein	A0A2H4PQH0	Staphylococcus_phage	3.8e-113	94.4
WP_000581552.1\|1909528_1910290_-	lantibiotic immunity ABC transporter MutE/EpiE family permease subunit	A0A2H4PQH2	Staphylococcus_phage	4.4e-131	100.0
WP_001096791.1\|1910286_1910979_-	lantibiotic protection ABC transporter ATP-binding subunit	A0A2H4PQG7	Staphylococcus_phage	6.2e-124	100.0
WP_000691541.1\|1911001_1912375_-	S8 family serine peptidase	A0A2H4PQH1	Staphylococcus_phage	2.9e-258	100.0
WP_000504439.1\|1912384_1912903_-	flavoprotein	A0A2H4PQG9	Staphylococcus_phage	2.0e-95	100.0
WP_000566596.1\|1912918_1914163_-	lanthionine synthetase C family protein	A0A2H4PQH9	Staphylococcus_phage	5.1e-238	100.0
WP_001092608.1\|1914155_1917149_-	lantibiotic dehydratase	A0A2H4PQG8	Staphylococcus_phage	0.0e+00	97.0
WP_000416756.1\|1917213_1917357_-	gallidermin/nisin family lantibiotic	A0A2H4PQH4	Staphylococcus_phage	5.3e-14	80.9
WP_000416759.1\|1918093_1918237_-	gallidermin/nisin family lantibiotic	NA	NA	NA	NA
WP_000782464.1\|1918478_1919462_-	bi-component leukocidin LukED subunit D	A0A2H4PQH7	Staphylococcus_phage	2.3e-185	99.1
WP_000473596.1\|1919463_1920399_-	bi-component leukocidin LukED subunit E	A0A2H4PQI5	Staphylococcus_phage	1.4e-174	100.0
WP_001086056.1\|1921295_1921751_+	hypothetical protein	Q4ZCB9	Staphylococcus_virus	6.3e-61	76.2
WP_000206350.1\|1921763_1922552_+	DUF1828 domain-containing protein	A0A2H4PQI0	Staphylococcus_phage	5.3e-140	95.8

DBSCAN-SWA_9

2016638 : 2103827

102

Staphylococcus_phage(91.3%)

capsid,protease,head,portal,tail,holin,integrase,terminase

attL 2053396:2053413|attR 2099856:2099873

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000827761.1\|2016638_2017805_+\|protease	cysteine protease staphopain A	NA	NA	NA	NA
WP_000434534.1\|2017835_2018162_+	staphostatin A	NA	NA	NA	NA
WP_000669861.1\|2018453_2018627_-	NETI motif-containing protein	NA	NA	NA	NA
WP_000011542.1\|2018607_2019210_-	DUF2179 domain-containing protein	NA	NA	NA	NA
WP_000040866.1\|2019480_2020302_-	ammonia-dependent NAD(+) synthetase	G3MA24	Bacillus_virus	2.3e-69	52.7
WP_000284425.1\|2020294_2021764_-	nicotinate phosphoribosyltransferase	G3MA18	Bacillus_virus	1.7e-107	45.1
WP_000897635.1\|2021947_2023024_+	nitric oxide synthase oxygenase	NA	NA	NA	NA
WP_001177816.1\|2023043_2023838_+	prephenate dehydratase	NA	NA	NA	NA
WP_001802312.1\|2023909_2024017_+	hypothetical protein	NA	NA	NA	NA
WP_000323164.1\|2024027_2025590_-	SLC13 family permease	NA	NA	NA	NA
WP_000275710.1\|2025794_2026892_-	pectate lyase	U5PWM6	Bacillus_phage	1.6e-46	34.3
WP_000149686.1\|2027263_2027824_+	cysteine hydrolase	G3MA16	Bacillus_virus	2.0e-32	41.2
WP_001140871.1\|2027876_2028806_+	manganese-dependent inorganic pyrophosphatase	NA	NA	NA	NA
WP_001790680.1\|2029000_2029174_-	hypothetical protein	NA	NA	NA	NA
WP_001021214.1\|2029225_2030605_+	aldehyde dehydrogenase	NA	NA	NA	NA
WP_000181322.1\|2030724_2031753_-	lactonase family protein	NA	NA	NA	NA
WP_000205106.1\|2032022_2032424_+	YolD-like family protein	U3PG23	Staphylococcus_phage	6.0e-23	42.9
WP_000267034.1\|2032996_2033170_-	hypothetical protein	NA	NA	NA	NA
WP_001188043.1\|2033620_2034661_+	linear amide C-N hydrolase	NA	NA	NA	NA
WP_000713072.1\|2034717_2035560_-	DUF4097 family beta strand repeat protein	NA	NA	NA	NA
WP_001033971.1\|2035556_2036114_-	DUF1700 domain-containing protein	NA	NA	NA	NA
WP_000966288.1\|2036173_2036698_-	membrane protein	NA	NA	NA	NA
WP_000182842.1\|2036818_2037382_+	thioredoxin family protein	NA	NA	NA	NA
WP_001221657.1\|2037447_2038188_-	phenol-soluble modulin export ABC transporter permease subunit PmtD	NA	NA	NA	NA
WP_000763048.1\|2038187_2039060_-	phenol-soluble modulin export ABC transporter ATP-binding protein PmtC	A0A2H4PQG7	Staphylococcus_phage	6.1e-28	35.2
WP_000645726.1\|2039056_2039737_-	phenol-soluble modulin export ABC transporter permease subunit PmtB	NA	NA	NA	NA
WP_000991301.1\|2039737_2040634_-	phenol-soluble modulin export ABC transporter ATP-binding protein PmtA	A0A2H4PQG7	Staphylococcus_phage	1.1e-16	30.2
WP_000691584.1\|2040630_2041011_-	GntR family transcriptional regulator	NA	NA	NA	NA
WP_000681968.1\|2041269_2041446_-	hypothetical protein	NA	NA	NA	NA
WP_000990056.1\|2041688_2041787_-	hypothetical protein	NA	NA	NA	NA
WP_001068523.1\|2041986_2043273_+	aminotransferase class I/II-fold pyridoxal phosphate-dependent enzyme	NA	NA	NA	NA
WP_001793419.1\|2043901_2045647_-	MAP domain-containing protein	NA	NA	NA	NA
WP_000669791.1\|2046604_2046784_+	hypothetical protein	A0A1W6JQ29	Staphylococcus_phage	1.4e-24	98.3
WP_001791826.1\|2047094_2047355_+	hypothetical protein	M9NS66	Staphylococcus_phage	2.3e-23	100.0
WP_000702263.1\|2047407_2047758_-	complement inhibitor SCIN-A	A0A1P8L6B0	Staphylococcus_phage	7.5e-54	100.0
WP_000920039.1\|2049255_2049747_-	staphylokinase	A0A1W6JQ12	Staphylococcus_phage	6.8e-85	98.8
WP_000861038.1\|2049937_2050693_-	CHAP domain-containing protein	D2JLG5	Staphylococcus_phage	3.4e-152	100.0
WP_000611512.1\|2050704_2050959_-\|holin	phage holin	D2JLG4	Staphylococcus_phage	4.1e-41	100.0
WP_031762631.1\|2051010_2051118_+	hypothetical protein	NA	NA	NA	NA
WP_011447039.1\|2051170_2051347_-\|holin	putative holin-like toxin	D2JLG3	Staphylococcus_phage	2.2e-22	98.3
WP_000750412.1\|2051455_2052229_-	staphylococcal enterotoxin type A	A0A1X9H080	Staphylococcus_phage	1.1e-145	100.0
WP_000340977.1\|2052601_2052976_-	hypothetical protein	G4KNR3	Staphylococcus_phage	3.3e-39	100.0
WP_001262624.1\|2053031_2053319_-	hypothetical protein	A0A1X9H0N7	Staphylococcus_phage	2.2e-43	98.9
WP_001000058.1\|2053364_2053517_-	hypothetical protein	A0A1W6JPL6	Staphylococcus_phage	7.6e-19	100.0
2053396:2053413	attL	NA	NA	NA	NA
WP_000582131.1\|2053509_2057292_-	hypothetical protein	A0A1X9H096	Staphylococcus_phage	0.0e+00	99.5
WP_001154317.1\|2057307_2058798_-\|tail	phage tail family protein	R9QST9	Staphylococcus_phage	3.1e-298	100.0
WP_001133533.1\|2058797_2063447_-\|tail	phage tail tape measure protein	A0A1V0E5H1	Staphylococcus_phage	0.0e+00	94.7
WP_000570353.1\|2063502_2063625_-	hypothetical protein	D2JLF6	Staphylococcus_phage	6.9e-15	100.0
WP_000442601.1\|2063684_2064131_-	hypothetical protein	D2JLF5	Staphylococcus_phage	5.4e-73	100.0
WP_000570652.1\|2064195_2065149_-	Ig-like domain-containing protein	A7TWD0	Staphylococcus_phage	6.2e-175	100.0
WP_000611454.1\|2065149_2065530_-	hypothetical protein	D2JLF3	Staphylococcus_phage	2.2e-67	99.2
WP_000501244.1\|2065526_2065904_-	HK97 gp10 family phage protein	D2JLF2	Staphylococcus_phage	1.1e-61	100.0
WP_000975314.1\|2065903_2066239_-\|head,tail	head-tail adaptor protein	A7TWC7	Staphylococcus_phage	1.1e-59	100.0
WP_001177483.1\|2066225_2066558_-\|head,tail	phage head-tail connector protein	D2JLF0	Staphylococcus_phage	2.1e-58	100.0
WP_001252099.1\|2066566_2066725_-	hypothetical protein	D2JLE9	Staphylococcus_phage	3.2e-20	100.0
WP_000849950.1\|2066760_2068008_-\|capsid	phage major capsid protein	A7TWC4	Staphylococcus_phage	5.0e-209	100.0
WP_000032525.1\|2068095_2068680_-\|head,protease	HK97 family phage prohead protease	D2JLE7	Staphylococcus_phage	9.8e-107	100.0
WP_000511065.1\|2068672_2069923_-\|portal	phage portal protein	D2JLE6	Staphylococcus_phage	4.8e-236	99.8
WP_000365299.1\|2069928_2070129_-	hypothetical protein	A0A1P8L6D3	Staphylococcus_phage	5.8e-27	100.0
WP_000133304.1\|2070142_2071837_-\|terminase	phage terminase large subunit	D2JLE4	Staphylococcus_phage	0.0e+00	100.0
WP_000919026.1\|2071839_2072307_-\|terminase	phage terminase small subunit P27 family	D2JLE3	Staphylococcus_phage	1.1e-81	100.0
WP_000817289.1\|2072435_2072780_-	HNH endonuclease	D2JLE2	Staphylococcus_phage	4.2e-65	100.0
WP_000406191.1\|2072795_2073248_-	nucleoside triphosphate pyrophosphohydrolase family protein	D2JLE1	Staphylococcus_phage	1.4e-79	100.0
WP_000282755.1\|2073362_2073833_-	hypothetical protein	D2JLE0	Staphylococcus_phage	1.7e-69	99.3
WP_001570807.1\|2073855_2074056_-	DUF1514 family protein	A0A2I6PDV9	Staphylococcus_phage	4.0e-28	98.5
WP_001005262.1\|2074055_2074706_-	hypothetical protein	D2JLD8	Staphylococcus_phage	8.9e-117	100.0
WP_000595265.1\|2074864_2075014_-	transcriptional activator RinB	A0A1W6JPZ2	Staphylococcus_phage	4.8e-18	100.0
WP_000401978.1\|2075354_2075759_-	RusA family crossover junction endodeoxyribonuclease	A0A0H3U2W2	Staphylococcus_phage	6.9e-67	91.0
WP_000338527.1\|2075767_2075986_-	hypothetical protein	A0A1P8L6E4	Staphylococcus_phage	4.0e-37	98.6
WP_000148328.1\|2075992_2076886_-	DnaD domain-containing protein	A0A0E3TAG7	Staphylococcus_phage	1.6e-137	97.6
WP_000934765.1\|2076915_2077386_-	single-stranded DNA-binding protein	A0A1P8L6D9	Staphylococcus_phage	7.7e-78	96.2
WP_072353921.1\|2077386_2078004_-	MBL fold metallo-hydrolase	A0A1W6JPL3	Staphylococcus_phage	1.3e-85	98.1
WP_000138475.1\|2078084_2079005_-	recombinase RecT	A0A2I6PDH5	Staphylococcus_phage	2.3e-166	100.0
WP_047211354.1\|2079006_2080962_-	AAA family ATPase	A0A2I6PDH3	Staphylococcus_phage	0.0e+00	98.6
WP_001205732.1\|2080958_2081222_-	hypothetical protein	A0A2I6PDG2	Staphylococcus_phage	7.7e-43	100.0
WP_000291488.1\|2081230_2081491_-	DUF1108 family protein	A0A2I6PDH1	Staphylococcus_phage	2.6e-43	100.0
WP_000066020.1\|2081583_2081745_-	DUF1270 domain-containing protein	A0A2I6PDF7	Staphylococcus_phage	1.9e-20	100.0
WP_001120197.1\|2081741_2082062_-	DUF771 domain-containing protein	A0A2I6PDH6	Staphylococcus_phage	1.5e-56	100.0
WP_000275058.1\|2082120_2082753_+	hypothetical protein	A7TW95	Staphylococcus_phage	1.5e-113	100.0
WP_000939496.1\|2082767_2082908_-	hypothetical protein	A0A2I6PDG0	Staphylococcus_phage	1.9e-16	100.0
WP_001148861.1\|2082938_2083136_-	hypothetical protein	A0A1W6JPV3	Staphylococcus_phage	1.2e-24	100.0
WP_001148337.1\|2083151_2083901_-	phage antirepressor KilAC domain-containing protein	Q8SDM9	Staphylococcus_phage	4.4e-136	99.6
WP_000351243.1\|2083957_2084497_+	hypothetical protein	A7TW92	Staphylococcus_phage	1.7e-97	100.0
WP_000435341.1\|2084520_2084781_-	transcriptional regulator	A7TW91	Staphylococcus_phage	2.7e-40	100.0
WP_000338186.1\|2084798_2085023_-	DUF739 family protein	A7TW90	Staphylococcus_phage	4.5e-36	100.0
WP_001208482.1\|2085181_2085952_+	helix-turn-helix domain-containing protein	A0A1P8L6G7	Staphylococcus_phage	6.2e-141	100.0
WP_001033320.1\|2086147_2086876_+	staphylococcal enterotoxin type Q	A0EX09	Staphylococcus_phage	2.3e-28	34.9
WP_000733771.1\|2086899_2087628_+	staphylococcal enterotoxin type K	A0EX09	Staphylococcus_phage	6.4e-23	32.3
WP_000857194.1\|2087711_2088749_+\|integrase	site-specific integrase	E9LT82	Staphylococcus_phage	1.0e-194	99.7
WP_000595401.1\|2089867_2090884_-	bi-component leukocidin LukGH subunit G	A0A2I6PER8	Staphylococcus_phage	2.3e-26	29.3
WP_000791417.1\|2090905_2091958_-	bi-component leukocidin LukGH subunit H	A0A2I6PDF3	Staphylococcus_phage	1.6e-35	32.1
WP_000206623.1\|2092393_2093617_+	ArgE/DapE family deacylase	NA	NA	NA	NA
WP_000812008.1\|2093988_2094834_-	class I SAM-dependent methyltransferase	NA	NA	NA	NA
WP_000825510.1\|2094895_2095807_-	iron-hydroxamate ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_001045079.1\|2095967_2097275_+	TrkH family potassium uptake protein	NA	NA	NA	NA
WP_000022887.1\|2098128_2098572_-	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_072419900.1\|2098677_2099115_-	hypothetical protein	NA	NA	NA	NA
WP_001293059.1\|2099431_2100022_-\|terminase	terminase small subunit	Q4ZE85	Staphylococcus_phage	1.2e-96	94.7
2099856:2099873	attR	NA	NA	NA	NA
WP_000128898.1\|2100018_2100231_-	hypothetical protein	Q4ZE86	Staphylococcus_phage	1.1e-23	74.3
WP_000240642.1\|2100932_2102549_-	chaperonin GroEL	A0A240F779	uncultured_virus	3.4e-157	54.7
WP_000917289.1\|2102624_2102909_-	co-chaperone GroES	A0A221S386	uncultured_virus	4.7e-14	46.2
WP_000197635.1\|2103083_2103827_+\|protease	CPBP family intramembrane metalloprotease	NA	NA	NA	NA

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. NC_003923

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CRISPR-Cas detection and classification

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Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection