CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NC_006351	Burkholderia pseudomallei K96243 chromosome 2, complete sequence	2 crisprs	cas3,DinG,csa3	0	0	6	0
NC_006350	Burkholderia pseudomallei K96243 chromosome 1, complete sequence	3 crisprs	RT,WYL,DEDDh,DinG,csa3,cas3	0	1	7	0

Results visualization

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CRISPR-Cas detection and classification

Crispr_ID: NC_006351_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_006351_1

2635599-2635691

Orphan

Consensus_repeat	Method
GCGCGTCGGCGCGCGCGGCGGCGA	CRISPRCasFinder

1 spacers

The CRISPR arrays of NC_006351_1

>merge|NC_006351|1|2635599-2635691|CRISPRCasFinder
GCGCGTCGGCGCGCGCGGCGGCGATCAGCCGCTCGCGCTCGGCGGCGGCCTGCGCGAGCGCGTCCTTCAGCGCGTCGTCGCGCGCGGCGGCGA

>NC_006351|1|1|2635599-2635691|CRISPRCasFinder
GCGCGTCGGCGCGCGCGGCGGCGA	TCAGCCGCTCGCGCTCGGCGGCGGCCTGCGCGAGCGCGTCCTTCA
GCGCGTCGTCGCGCGCGGCGGCGA

Protein	Signature genes	Signature genes Name	Protein_function
NC_006351.1\|WP_004188221.1\|2637650_2638106_-\|F0F1-ATP-synthase-subunit-epsilon	unknown	unknown	gnl\|CDD\|184057
NC_006351.1\|WP_004524995.1\|2620062_2621136_+\|HlyD-family-efflux-transporter-periplasmic-adaptor-subunit	unknown	unknown	gnl\|CDD\|235136
NC_006351.1\|WP_009972311.1\|2632317_2633166_-\|F0F1-ATP-synthase-subunit-gamma	unknown	unknown	gnl\|CDD\|376304
NC_006351.1\|WP_004533317.1\|2630497_2631013_-\|hypothetical-protein	unknown	unknown	unknown
NC_006351.1\|WP_004552098.1\|2625633_2627469_+\|response-regulator	unknown	unknown	gnl\|CDD\|237425
NC_006351.1\|WP_004552097.1\|2624359_2625484_+\|ABC-transporter-permease	unknown	unknown	gnl\|CDD\|223912
NC_006351.1\|WP_004187193.1\|2635909_2636158_-\|F0F1-ATP-synthase-subunit-C	unknown	unknown	gnl\|CDD\|184067
NC_006351.1\|WP_009950383.1\|2640072_2641866_+\|polyhydroxyalkanoic-acid-synthase	unknown	unknown	gnl\|CDD\|213656
NC_006351.1\|WP_004540302.1\|2643276_2644455_+\|acetate/propionate-family-kinase	unknown	unknown	gnl\|CDD\|235922
NC_006351.1\|WP_004524990.1\|2627824_2629390_-\|methyl-accepting-chemotaxis-protein	unknown	unknown	gnl\|CDD\|185008
NC_006351.1\|WP_045606127.1\|2638095_2639712_-\|F0F1-ATP-synthase-subunit-beta	unknown	unknown	gnl\|CDD\|183615
NC_006351.1\|WP_162486647.1\|2645186_2646608_-\|hexose-kinase	unknown	unknown	gnl\|CDD\|238570
NC_006351.1\|WP_011205710.1\|2633162_2635163_-\|F0F1-ATP-synthase-subunit-alpha	unknown	unknown	gnl\|CDD\|183987
NC_006351.1\|WP_004530237.1\|2637153_2637654_-\|AtpZ/AtpI-family-protein	unknown	unknown	gnl\|CDD\|378198
NC_006351.1\|WP_011205708.1\|2621132_2624357_+\|ATP-binding-cassette-domain-containing-protein	unknown	unknown	gnl\|CDD\|224054
NC_006351.1\|WP_004187346.1\|2636154_2636856_-\|F0F1-ATP-synthase-subunit-A	unknown	unknown	gnl\|CDD\|237383
NC_006351.1\|WP_004524980.1\|2641876_2643280_+\|bifunctional-enoyl-CoA-hydratase/phosphate-acetyltransferase	unknown	unknown	gnl\|CDD\|236180
NC_006351.1\|WP_004201694.1\|2636852_2637161_-\|membrane-protein	unknown	unknown	gnl\|CDD\|274462
NC_006351.1\|WP_004524989.1\|2629930_2630440_+\|hypothetical-protein	unknown	unknown	unknown
NC_006351.1\|WP_011205709.1\|2631077_2632103_-\|alcohol-dehydrogenase-AdhP	unknown	unknown	gnl\|CDD\|176257

Protein	Function_ID	Function_description	E-value
NC_006351.1\|WP_004188221.1\|2637650_2638106_-\|F0F1-ATP-synthase-subunit-epsilon	gnl\|CDD\|184057	PRK13447, PRK13447, F0F1 ATP synthase subunit epsilon; Provisional.	4.44077e-63
NC_006351.1\|WP_004524995.1\|2620062_2621136_+\|HlyD-family-efflux-transporter-periplasmic-adaptor-subunit	gnl\|CDD\|235136	PRK03598, PRK03598, putative efflux pump membrane fusion protein; Provisional.	1.83012e-39
NC_006351.1\|WP_004524990.1\|2627824_2629390_-\|methyl-accepting-chemotaxis-protein	gnl\|CDD\|185008	PRK15048, PRK15048, methyl-accepting chemotaxis protein II; Provisional.	2.47951e-79
NC_006351.1\|WP_004552098.1\|2625633_2627469_+\|response-regulator	gnl\|CDD\|237425	PRK13557, PRK13557, histidine kinase; Provisional.	6.12457e-132
NC_006351.1\|WP_004552097.1\|2624359_2625484_+\|ABC-transporter-permease	gnl\|CDD\|223912	COG0842, COG0842, ABC-type multidrug transport system, permease component [Defense mechanisms].	1.904e-25
NC_006351.1\|WP_004187193.1\|2635909_2636158_-\|F0F1-ATP-synthase-subunit-C	gnl\|CDD\|184067	PRK13468, PRK13468, F0F1 ATP synthase subunit C; Provisional.	4.45015e-37
NC_006351.1\|WP_009950383.1\|2640072_2641866_+\|polyhydroxyalkanoic-acid-synthase	gnl\|CDD\|213656	TIGR01838, Poly-beta-hydroxybutyrate_polymerase, poly(R)-hydroxyalkanoic acid synthase, class I. This model represents the class I subfamily of poly(R)-hydroxyalkanoate synthases, which polymerizes hydroxyacyl-CoAs with three to five carbons in the hydroxyacyl backbone into aliphatic esters termed poly(R)-hydroxyalkanoic acids. These polymers accumulate as carbon and energy storage inclusions in many species and can amount to 90 percent of the dry weight of cell. [Fatty acid and phospholipid metabolism, Biosynthesis].	1.63529e-179
NC_006351.1\|WP_004540302.1\|2643276_2644455_+\|acetate/propionate-family-kinase	gnl\|CDD\|235922	PRK07058, PRK07058, acetate/propionate family kinase.	0
NC_006351.1\|WP_009972311.1\|2632317_2633166_-\|F0F1-ATP-synthase-subunit-gamma	gnl\|CDD\|376304	pfam00231, ATP-synt, ATP synthase.	1.49395e-33
NC_006351.1\|WP_045606127.1\|2638095_2639712_-\|F0F1-ATP-synthase-subunit-beta	gnl\|CDD\|183615	PRK12597, PRK12597, F0F1 ATP synthase subunit beta; Provisional.	0
NC_006351.1\|WP_162486647.1\|2645186_2646608_-\|hexose-kinase	gnl\|CDD\|238570	cd01164, FruK_PfkB_like, 1-phosphofructokinase (FruK), minor 6-phosphofructokinase (pfkB) and related sugar kinases. FruK plays an important role in the predominant pathway for fructose utilisation.This group also contains tagatose-6-phophate kinase, an enzyme of the tagatose 6-phosphate pathway, which responsible for breakdown of the galactose moiety during lactose metabolism by bacteria such as L. lactis.	1.21157e-108
NC_006351.1\|WP_011205710.1\|2633162_2635163_-\|F0F1-ATP-synthase-subunit-alpha	gnl\|CDD\|183987	PRK13343, PRK13343, F0F1 ATP synthase subunit alpha; Provisional.	0
NC_006351.1\|WP_004530237.1\|2637153_2637654_-\|AtpZ/AtpI-family-protein	gnl\|CDD\|378198	pfam09527, ATPase_gene1, Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter. This model represents a protein found encoded in F1F0-ATPase operons in several genomes, including Methanosarcina barkeri (archaeal) and Chlorobium tepidum (bacterial). It is a small protein (about 100 amino acids) with long hydrophobic stretches and is presumed to be a subunit of the enzyme. It carries two transmembrane helices and is a magnesium or calcium uniporter. The atp operon of alkaliphilic Bacillus pseudofirmus OF4, as in most prokaryotes, contains the eight structural genes for the F-ATPase (ATP synthase), which are preceded by an atpI gene that encodes a membrane protein with 2 TMSs. A tenth gene, atpZ, has been found in this operon, which is upstream of and overlapping with atpI.	4.39073e-17
NC_006351.1\|WP_011205708.1\|2621132_2624357_+\|ATP-binding-cassette-domain-containing-protein	gnl\|CDD\|224054	COG1131, CcmA, ABC-type multidrug transport system, ATPase component [Defense mechanisms].	2.27123e-92
NC_006351.1\|WP_004187346.1\|2636154_2636856_-\|F0F1-ATP-synthase-subunit-A	gnl\|CDD\|237383	PRK13421, PRK13421, F0F1 ATP synthase subunit A; Provisional.	1.54059e-122
NC_006351.1\|WP_004524980.1\|2641876_2643280_+\|bifunctional-enoyl-CoA-hydratase/phosphate-acetyltransferase	gnl\|CDD\|236180	PRK08190, PRK08190, bifunctional enoyl-CoA hydratase/phosphate acetyltransferase; Validated.	0
NC_006351.1\|WP_004201694.1\|2636852_2637161_-\|membrane-protein	gnl\|CDD\|274462	TIGR03165, F1F0_chp_2, F1/F0 ATPase, Methanosarcina type, subunit 2. Members of this protein family are uncharacterized, highly hydrophobic proteins encoded in the middle of apparent F1/F0 ATPase operons. We note, however, that this protein is both broadly and sparsely distributed. It is found in about only about two percent of microbial genomes sequenced, with the first ten examples found coming from the Euryarchaeota, Chlorobia, Betaproteobacteria, Deltaproteobacteria, and Planctomycetes. In most of these species, surrounding operon appears to represent a second F1/F0 ATPase system, and the member proteins belong to subfamilies with the same phylogenetic distribution as the current protein family.	3.23546e-10
NC_006351.1\|WP_011205709.1\|2631077_2632103_-\|alcohol-dehydrogenase-AdhP	gnl\|CDD\|176257	cd08297, CAD3, Cinnamyl alcohol dehydrogenases (CAD). These alcohol dehydrogenases are related to the cinnamyl alcohol dehydrogenases (CAD), members of the medium chain dehydrogenase/reductase family. NAD(P)(H)-dependent oxidoreductases are the major enzymes in the interconversion of alcohols and aldehydes, or ketones. Cinnamyl alcohol dehydrogenases (CAD) reduce cinnamaldehydes to cinnamyl alcohols in the last step of monolignal metabolism in plant cells walls. CAD binds 2 zinc ions and is NADPH- dependent. CAD family members are also found in non-plant species, e.g. in yeast where they have an aldehyde reductase activity. The medium chain dehydrogenases/reductase (MDR)/zinc-dependent alcohol dehydrogenase-like family, which contains the zinc-dependent alcohol dehydrogenase (ADH-Zn) and related proteins, is a diverse group of proteins related to the first identified member, class I mammalian ADH. MDRs display a broad range of activities and are distinguished from the smaller short chain dehydrogenases (~ 250 amino acids vs. the ~ 350 amino acids of the MDR). The MDR proteins have 2 domains: a C-terminal NAD(P) binding-Rossmann fold domain of a beta-alpha form and an N-terminal catalytic domain with distant homology to GroES. The MDR group contains a host of activities, including the founding alcohol dehydrogenase (ADH), quinone reductase, sorbitol dehydrogenase, formaldehyde dehydrogenase, butanediol DH, ketose reductase, cinnamyl reductase, and numerous others. The zinc-dependent alcohol dehydrogenases (ADHs) catalyze the NAD(P)(H)-dependent interconversion of alcohols to aldehydes or ketones. Active site zinc has a catalytic role, while structural zinc aids in stability. ADH-like proteins typically form dimers (typically higher plants, mammals) or tetramers (yeast, bacteria), and generally have 2 tightly bound zinc atoms per subunit. The active site zinc is coordinated by a histidine, two cysteines, and a water molecule. The second zinc seems to play a structural role, affects subunit interactions, and is typically coordinated by 4 cysteines.	3.61973e-180

>NC_006351.1|WP_011205710.1|2633162_2635163_-|F0F1-ATP-synthase-subunit-alpha
MTPTPDAPAAAAADAATGAGWLARRRGALARVALAPVAQAIGRVERVADGIAFVSGLEDTMLNEVLRFEGGVTGFAHTLDEDLISVVLLDPDAGVRAQTAVARTGAVLEVPAGPQLLGRVVDPLGRPLDGGAPLDAAHTLPIERAAPAIIERDLVSEPLDTGVLIVDALFTIGRGQRELIIGDRATGKTSLAIDAIVNQRHSDVICVYVAIGQRASAVRRVIDAVRRYGAPERCVFVVAPAACAPGLQWIAPFAGFSIAEYFRDRGQHALVVVDDLTKHAATHRELALLTREPPGREAYPGDIFYVHARLLERAAKLSAALGGGSLSALPIAETDAGNLAAYIPTNLISITDGQIVLDSALFAANQRPAVDVGLSVSRVGGKAQHPALRAASGRLRLDYAQFLELEAFTRFGGLTDARLRAQITRGERIRALITQPRFRALRTLDEVVLLKALAAGALDAMSPDLVAPLRERLPAWLDARIAALTPALAPPRDWLADDAALDALAESVGELIERIAADAARRATAGMPAEDAAGDIGGAFGGEQARGDADRDADHGANREVSREVSPEASREVSREVSCEVSHEADRDAAADAARVAGRAPGRAEPDRAAPRAMPDGPPRAQADGDRASASRPRPDARGDAARTAPSPQGGADANVDAEAEARHKR
>NC_006351.1|WP_009972311.1|2632317_2633166_-|F0F1-ATP-synthase-subunit-gamma
MSDKLAAIEARTDTARQLQTVIGAMQGVAAARAHEAQQRLPGIRASAATVGAAIGDALSAGARSGETAAGARAAPRARLVVVLCSEQGFVGAYNAQLIEHATRPGPSVSREYMMVGSRGAMLADAGGVPLVWRTPMAARADDVVHLANRITDALYAHLAKRGAQPVSIVHAMPGGAARLEVTERRLLPFDYARFDTAPRAQPPLVHLPPATLLAELAQAYVFVELCEAAMLAFAAENEARTRAMIAARESVERALGDLLQAYRIARQDEITADIVELAASGL
>NC_006351.1|WP_011205709.1|2631077_2632103_-|alcohol-dehydrogenase-AdhP
MAQYMKAAVVHAFGEPLRIEEVPVPTPGAGQILVNVKASGVCHTDLHAADGDWPVKPTLPFIPGHEGVGFVAAVGEGVRHVKEGDRVGVPWLYTACGHCEYCQTGWETLCHEQQNTGYSVYGSYAEYVLADPNYVGHLPSNVAFDEIAPILCAGVTVYKGIRVTDTRPGQWIAISGIGGLGHVAVQYAKAMGLHVVAVDVAPQKLELARKLGAAFVVDASKDDPAAVIQKEIGGVHGVLVTAVSRGAFAQALGMVRRGGTVSLNGLPPGDFPLPIFSTVLNGITVRGSIVGTRRDLQESLDFAAEGLVRAHIHRDKLEHINGVFSALREGKVDGRIVLTGQ
>NC_006351.1|WP_004533317.1|2630497_2631013_-|hypothetical-protein
MRRAMRGAGRASPSRARRYENVSKEPNTHREAGAPVHRYRLQVRNMNGECRTYELRLSSLDDGYTLEIDEWLNFPDMHLGDVTPVHVSRPVQFAVPAHEFYRRRRAFRTELIESVAAALRAGEVVRMRDSPDEYPGGHAGNPWVNWIRADLRANPGGRPPPVGDDMQDLIH
>NC_006351.1|WP_004524989.1|2629930_2630440_+|hypothetical-protein
MRRIYFLLPDADTARAIVDELLLKRIEWRHIHVVANDRVPLENLPEASIAQSSDLLPALARGTAAGGVTGALAGLAAIAFPPAGLTIAGGAVVAFAIAGAGFGAWVGTMIGVSVPNTRLKHFEDAVDNGELLMMIDVHRDRVEEIEALVKQHHPNAHLEGTDPTIPAFP
>NC_006351.1|WP_004524990.1|2627824_2629390_-|methyl-accepting-chemotaxis-protein
MPTLSFRQKLWLPLVISLIALLLVSISSAWLSYQTRMEERRNDLTNVAHVGLSIVREYAALAQRGVLTDAQARKEALERLRSVRYGSDGYFIVIDSSPRMIMHPIKPDTVGKDLRHVADADGRHHYLTFASVAQSPQGGFVDYVFAHPNAHPAKAVDKLGYVIRYAPWDWIISTGAYIDDIQAAFAKSLCLSAGVFALLAALLALSVVYTNRGIERMIGGDPRIAAHMAGVIASGDLATPFATRREDRSSLMFAISQMRDALANAVAQIRASAGYVATTAGEIADSNMDLSSHTECQATALQQAASSMQRLTERVRDTADRARAASELAGSAARITDRGGDMVVRVVAAMNDIRAESRKMVDIIGVIEGIAFQTNILALNAAVEAARAGNEGRGFAVVASEVRVLAQRSASAAKDIRALIGRAAERVGNGAELVEATGATIGEAQHAICRVTGIVQDIAAAATDQSQGLEQINAAVSQMDSVTRRNATLVEHAAIAAQSLNEQSRCLQDAVAAFRTEALGC
>NC_006351.1|WP_004552098.1|2625633_2627469_+|response-regulator
MHVEVFAQHSSCPGWHGEMARRIRAFDWSATELGPLERWPASLVAAVRTVLASPVPLVMLWGASGYMLYNDAYAAFAGGRHPYLLGQPVELGWPEVADFNRNVMRTCLAGGALSYRDKALVLLRNGRPEEVWMDLYYSPLAGDDGAPAGVLAVVVETTERVLAARHRDRAKAALHETNAELRRLTETLEQRVADAITERASIEEQLRQAQKMEAIGSLTGGIAHDFNNVLQVVSSNLQMLSAELGEDARAQRRIASAANAVARGAQLASHLLAFARRQPLAPAVLEPRGLIDGMREMLHRALGESVHVDADLRDDVWNVLADRHQFENALLNLAINARDAMRGEGTLKITACNIVLEAGRHARRNGLPPGEYVAFDIADNGVGMTPDILERVFEPFFTTKPDGQGTGLGLSMVFGFVKQSGGHTSIESAPGRGTTVRLLLPRCREAPAGEPAAQRRLPAEGGRETILVVEDDADVRLAVVDMLAQLGYKVITASDGEAGLLALESGAPIDLLFTDVIMPGRIKGGELARRAAQRVPPVPVLFTSGYTRDEIFHAGRLDPGVMLLGKPYRRDELAHKVRSVLDAHASARRARGARHAQADPRAKTAAARVQR
>NC_006351.1|WP_004552097.1|2624359_2625484_+|ABC-transporter-permease
MRRLAIVYRLGVKELWSLVRDPILLVLIAYTFTASIYSAATARPDTLHMAPIAIIDEDASPLSARIASAFFPPQFALPRMVTLAEADRGMNAGDFTFVLDIPPNFQRDVLAGRPAQIQLNVDATRMSQAFTGNGYVQQIVSGEIDDFARRYRANTAPPVDIAMHMRFNPNLDQTWFGSLMEVINNVTLLSMVLTGAALIREREHGTIEHLLVMPVTPGEIMLAKVWSMGLVVACAAAFSLAFVVRGALHVPIEGSVALFVIGMAIHLFATTSMGIFLATLVRSMPQFGMLLVLVLLPLQLLSGSLTPRESMPFAVQNIMLAAPTTHFVEIGQAILYRGAGIETVWRKFLILAVIGTALFLLSLKRFRKTIGQMA
>NC_006351.1|WP_011205708.1|2621132_2624357_+|ATP-binding-cassette-domain-containing-protein
MSAPSVVRFSDVSLRYGKTVALERITLEIPAGLTIGLIGPDGVGKSSLLALAAGARALQTGAVDALGGDMRSRRHRERVCRRIAYMPQGLGKNLYPTLSVEENLQFFARLFGHDADERRRRIDALTRSTGLFAFLSRPAGKLSGGMKQKLGLCCALIHDPDLLILDEPTTGVDPLARAQFWDLIARIRSERPAMSVIVATAYMDEAQRFDWLIAMDAGRVLATGAPAELLARTGCDSLEAAFIALLPEDERRGHKPVTLEPLRADAQTGTAIEARGLTMRFGDFTAVDHVSFRIRRGEIFGFLGSNGCGKSTTMKMLTGLLPATEGTAQLFGKTVDPKDINTRRRVGYMSQAFSLYSELTVRQNLVLHARLFGVPAAEIDARVDEMARRFGLADIYDMLPDSLPLGMRQRLSLAVAMVHKPELLILDEPTSGVDPVARDSFWQLMIDLARRDRVTIFISTHFMNEAQRCDRISLMHAGRVLASDAPAALVRARGAATLEEAFIGYLVDASAQEAQGGAGGRPGAGERAAGESLAGRGAATDGDADGAHARPAAYANGAAQHRAPDADAAGTDVAAETGARDDARTAHAAGHSAGNDVRATVGSEVGSEVASEAGLAASAESGSERGVAHGAERAREPAADAGAAIDVEPGASAESATAAVAPARHAESAATSPRAGNAPAGTPFAAAPPSHAAPAEPPHRAFSAQRALSYMWREMLELRRDPVRATLALIGSLVLMCVIGIGISLDVEDLTYAVLDRDQTELSHDYALNLSGSRYFVERPPIADYAALDRRMRDGELSLAIEIPPNFARDVERGAPAQIGMWIDGAMPQRAETIRGYAIGMHTMWLADKARHRLGVTLAPRAEVVTRYRYNPDVKSLPAMIPAVMPLLLLMLPAMLTALAVVRERELGSILNLYVTPVTRTEFLIGKQVPYVVLAMLNFLLMTMLARIAFDVPVKGSFMTLLLAVLIFNVVATGIGLLASTFTRSQVAAIVMTIIGTMIPTVQFAGLLTPLSSLEGTGRLIGLVYPATYMLSISRGVFNKALSLHDLYSQFWPLAASVPVILGATILLLKKQER
>NC_006351.1|WP_004524995.1|2620062_2621136_+|HlyD-family-efflux-transporter-periplasmic-adaptor-subunit
MIQVTRKQIVAAAAVVVVALGAYYGWTLLRHQGPGDGFASGNGRIEATEIDVATKLPGRIDAILVDEGDFVKAGQPLANMQIQVLRAQYDEATAQRQRALNTAAGVQSQVAQRKSDKAAAQAMVVLRESELDAAERRLARSQTLSREGASSLQELDDDRARARSAQAAVSAAAAQVAAAQAAIEATEAQLVAAHSAVTAADATVARVQADIDDSQLASPRDGRVQYRVAQPGEVLPAGGKVLNLVDLSDVYMTFFLPETVVGRVALGADARIILDAAPNYVIPATVSFVSSTAQFTPKTVETANERQKLMFRVKARIDRELLQKHLKLVKTGLPGVAWVRVDPSKPWPAQLMVKVPQ
>NC_006351.1|WP_004187193.1|2635909_2636158_-|F0F1-ATP-synthase-subunit-C
MNNLIEVVSIAAAALAVSFGAIGPALAEGRAVGAAMDAIARQPDASGTVSRTLFVGLAMIETMAIYCLVVALLLLFANPFVK
>NC_006351.1|WP_004187346.1|2636154_2636856_-|F0F1-ATP-synthase-subunit-A
MNASPLSTVPLFSVGPVGISAPVLATWAIMAVLVALALVARRRLSVDAPSRLQSVLELFVATVDAQIADTMQTPPARYRALIGTIFVLVFCANGASLVPGVEPPTAHLETDAALALVVLAATLYYGVRARGVRGYLATFAEPTWVMIPLNVVEQLTRTFSLIVRLFGNVMSGVFVIGIVLSLAGLFVPIPLMALDLLTGTVQAYIFMVLSMVFIGAAVSGDETSAPRRGQENT
>NC_006351.1|WP_004201694.1|2636852_2637161_-|membrane-protein
MIEMWETARASFDGIAAAIGLALGFAAGACHFVSLGWNSRLFVAGRAGVALALQFARVALAVAVLVVLARAGFGMLVAGSAGFFAARAIAVRRAAALTGARR
>NC_006351.1|WP_004530237.1|2637153_2637654_-|AtpZ/AtpI-family-protein
MMKRRPPEVKREAREARDDAARGDARHAGAGAAPDDPRGAARRDPPPGSRAARGGATHPAARAAEPAAPKPAADRVERAAHTAAARAARGARDPEPSLGRRLAQIGVLGWTIVAPTLAALALGRWLDRMFATRVFFSAPLLMLGAALGLWLAWRWMKAQQHGDRDD
>NC_006351.1|WP_004188221.1|2637650_2638106_-|F0F1-ATP-synthase-subunit-epsilon
MGAELRVTIATPARVCVDDLPIVSLRAEDASGAFGIRAGHVDFVTLLRASVVRWRTADGATHYAALDGGVLRVTRGARIEIACRDAVLGESLAELEAVVRGVRATQLDEKRRARVDETRLHAQAVRRLLTYLRPEHAKDGVHAPLKPETLE
>NC_006351.1|WP_045606127.1|2638095_2639712_-|F0F1-ATP-synthase-subunit-beta
MADPQATNGTGAACAERDASDVGDVSDVGDARDEGAGRVVAVRGAVVDVAFDGGALPALNEALTIPVDGASPILAEVHAHLSDAAVRALALGPTGGLRRGAAVRATGGPIRVPVGDAVLGRLLSVTGAPGDDGAALAADVERRPIHRGAPPLAEQKSANALFATGIKVIDLLAPLAQGGKAAMFGGAGVGKTVLVMELIHAMVERYRGISVFAGIGERSREGHEMLLDMRGSGVLGRTVLVYGQMNEPPGARWRVPLTALAIAEYFRDERAQNVLLLMDNVFRFVQAGAEVSGLLGRLPSRVGYQPTLASEVAALQERIASVEGAAVTAIEAVYVPADDFTDPAVTAIAAHVDSMVVLSRAMAAEGMYPAIDPVASSSILLDPLVVGEAHVEVAIEVRRVIEHYRELQDVIALLGIDELGADDRRLVGRARRLQRFLTQPFAVTEAFTGQAGASVEIADTIAGCRAILRGDCDDWRESSLYMVGTLDDARRKEAAAREADARREAAAAASVAGPGTTSGTTSDPASGSAEPQGARHGR
>NC_006351.1|WP_009950383.1|2640072_2641866_+|polyhydroxyalkanoic-acid-synthase
MDTRHAPESGAPDAPLPAHPPASYAPESPYRIFDLAKEASVAKLTSGLSPASLQLALADWLIHLAAAPGKRAELATLALRHAALLGQYLLEAATGRTPAAPAQPSPGDRRFRAGAWQLEPYRFWHQSFLLAEQWWRAATRDVPGVSPHHEDVVAFSARQMLDTFAPANYVATNPEIAQRTALTGGANLAQGVWNYLDDVRRLITKQPPAGAEQFELGRNLATTPGRVVFRNHLIELLQYSPTTPDVYAQPVLIVPAWIMKYYILDLSAHNSLIRYLVGEGHTVFCISWRNVDASDRDLSLDDYRKLGVMDALDTIGAIVPGEKIHATGYCLGGTLLSIAAAAMANTGDDRLASITLLAAQTDFAEPGELQLFIDDSEIHFLESMMWERGYLGAHQMAGSFQLLMSNDLIWSRVIHDYLLGERTPMIDLMAWNADSTRMPYRMHSEYLRHLFLDNDLATNRYVIDGQTVSVHNIRAPFFVVGTEHDHIAPWRSVYKIHYLSGSDVTFVLTAGGHNAGIVSEPGHAKRHYRMKMTAAAAPSISPDEWLAGATDFEGSWWPAWHAWLARHSSPQRVAPPPLGKPGARTLGDAPGTYVFQK
>NC_006351.1|WP_004524980.1|2641876_2643280_+|bifunctional-enoyl-CoA-hydratase/phosphate-acetyltransferase
MDREILQNRPFDSLAIGDSASLVRTASRDDIDLFAAMSGDVNPAHLDAAFAAHDLFGHVVVHGMWTGALVSAVLGTKLPGPGTIYLDQTLEFRHPVAPGDTITATVTVAEKRPEKRIVLLDTRCTNQDGHVVLRGTATVIAPDTPITWERVPGPEVAVRRHDRYETFVRDAREQPPLRTAIVHPCSPDALRAAIDARDANLIEPILIGPQAKIRAIADAAGVDLAGVPIEAVEHSHAAAARAVEMGGAGEVAALMKGSLHTDELLAAVIGPASRLRTERRISHVYAMDVPAYPKPLLITDAAINIAPTLEQKRDICQNAVDLLHVLGVERPRVAVLAAVETVNPKMPSTLDAAALTVMAARGQIAGAIVDGPLAFDNAVSAVAAMSKGIASPVAGDADVLLVPDLEAGNMLAKQLMYFAGADAAGLVLGARLPIILTSRADSLRVRIASAALAKLVAERTRAGALAS
>NC_006351.1|WP_004540302.1|2643276_2644455_+|acetate/propionate-family-kinase
MSEPLLLTFNAGSSTLKIGLYSVANGEPAPLGRGKIDFNRAPLQFEYANGGEAHAVPLAAPVTDDLHAVLDEALGWIDAHLSVHELVSVGHRVVHGGDTFDGPVRIDERTLDAIAALVPLAPLHQPQSVRLIRALRHVRPHLPQVASFDTAFHRTQSDLVRRFALPRALFDAGIKRYGFHGLSYRYVAGRLRERHPSIARGKVVAAHLGSGASLCALDAGVSRDTSMGFSTLDGIPMATRCGALDAGVVLHLQKTLGRTLDDVEQMLYHRSGLLGVSGVSGDARALLADPSAGARDALELFAFRIAGETARLAATLGGLDALVFTAGIGEHQPQTRAAVCERLRWLGVELDAHANARNAETVSRDGSRVAVLVVPTDEEQVIARDAASVLHA
>NC_006351.1|WP_162486647.1|2645186_2646608_-|hexose-kinase
MCAALARRARCSILAASGKRQAASGKRQAASGKRQAASGKRQAASGKRQAASGKRQAASGKRQAASGKRQAASGKRQAASGKRQAASGKRQAASGKQQAASSKQQAASSSRSSPGLMVRRRIERKHCGACPPRSTREPRTRASRCVVFPSRIPTLKPNVTMPEIVTLTPNPAIDVATCVERVTDTRKLRCGPARRDPGGGGINVARVLTRLGADCSAVYLAGGGTGLALRGLLADEGVRAHGIDIAGETRENFSVLETSTGREFRFVLPGPALAAHEWPRCVEALGRLADASRYLVMSGSLPPGMPDDCYARLARRASARGVRTVVDTSGPALAAALDAGVYLVKPSLGELRALTGLPLEDDGARLAAARAIVAGGRAQIVALTLGDAGALVVSRDDAVRLPGVKVAVRSAIGAGDSFVAGLVAALNRGANVADAARHALAAASASLLSTGTALGTKEDIARIYRELPGTIDA

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Crispr_ID: NC_006351_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_006351_2

3065942-3066087

Orphan

Consensus_repeat	Method
GCAGAGGCGCCGCCGCCGGAATACCCGATCATCGGGATGCTCGATCGCCGAAG	PILER-CR
CGGAATGCCCGATCATCGGGATGC	CRISPRCasFinder

2 spacers

The CRISPR arrays of NC_006351_2

>merge|NC_006351|2|3065942-3066087|PILER-CR,CRISPRCasFinder
TCGTCGGGATGCTCGATTGCCGCAGTCACCCTCCGCCGGGGCTCCGTCGTCGGAATGCCCGATCATCGGGATGCCTGCTCGCCGAAGCACTCCACCGCAGAGGCGCCGCCGCCGGAATACCCGATCATCGGGATGCTCGATCGCCG

>NC_006351|2|1|3065942-3066087|PILER-CR
TCGTCGGGATGCTCGATTGCCGCAGTCACCCTCCGCCGGGGCTCCGTCGTCGGAA	TGCCCGAT
CATCGGGATGCCTGCTCGCCGAAGCACTCCACCGCAGAGGCGCCGCCGCCGGAAT	ACCCGATCA
TCGGGATGCTCGATCGCCG

>NC_006351|2|2|3065992-3066077|CRISPRCasFinder
CGGAATGCCCGATCATCGGGATGC	CTGCTCGCCGAAGCACTCCACCGCAGAGGCGCCGCCGC
CGGAATACCCGATCATCGGGATGC

Protein	Signature genes	Signature genes Name	Protein_function
NC_006351.1\|WP_004552281.1\|3076640_3077294_+\|SagB/ThcOx-family-dehydrogenase	unknown	unknown	gnl\|CDD\|380318
NC_006351.1\|WP_004552282.1\|3078194_3079334_-\|porin	unknown	unknown	gnl\|CDD\|238208
NC_006351.1\|WP_004530665.1\|3073433_3075266_+\|STAS-domain-containing-protein	unknown	unknown	gnl\|CDD\|223732
NC_006351.1\|WP_004205322.1\|3058718_3059654_+\|LysR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|176109
NC_006351.1\|WP_004530663.1\|3075737_3076187_-\|CBS-domain-containing-protein	unknown	unknown	gnl\|CDD\|341411
NC_006351.1\|WP_004548017.1\|3059669_3060260_+\|hypothetical-protein	unknown	unknown	unknown
NC_006351.1\|WP_076848180.1\|3055788_3056145_-\|hypothetical-protein	unknown	unknown	unknown
NC_006351.1\|WP_004547986.1\|3079401_3081207_-\|fatty-acid--CoA-ligase	unknown	unknown	gnl\|CDD\|235730
NC_006351.1\|WP_004530666.1\|3072405_3073437_+\|nitroreductase-family-protein	unknown	unknown	gnl\|CDD\|236122
NC_006351.1\|WP_004530669.1\|3066654_3067926_+\|polyhydroxyalkanoate-depolymerase	unknown	unknown	gnl\|CDD\|130908
NC_006351.1\|WP_004523292.1\|3054056_3055289_-\|3-methyl-2-oxobutanoate-dehydrogenase-(2-methylpropanoyl-transferring)-subunit-alpha	unknown	unknown	gnl\|CDD\|223997
NC_006351.1\|WP_011205761.1\|3062507_3064781_-\|FAD-dependent-oxidoreductase	unknown	unknown	gnl\|CDD\|369639
NC_006351.1\|WP_004547976.1\|3060319_3062218_+\|GMC-family-oxidoreductase	unknown	unknown	gnl\|CDD\|225186
NC_006351.1\|WP_004529492.1\|3068153_3069995_+\|ribonucleotide-reductase-like-protein	unknown	unknown	gnl\|CDD\|180772
NC_006351.1\|WP_004196896.1\|3056259_3056421_-\|hypothetical-protein	unknown	unknown	unknown
NC_006351.1\|WP_004200700.1\|3057305_3058421_-\|SRPBCC-family-protein	unknown	unknown	gnl\|CDD\|378454
NC_006351.1\|WP_004529498.1\|3077354_3077789_-\|Hsp20/alpha-crystallin-family-protein	unknown	unknown	gnl\|CDD\|223149
NC_006351.1\|WP_004532595.1\|3070069_3071881_+\|bifunctional-aminoglycoside-phosphotransferase/ATP-binding-protein	unknown	unknown	gnl\|CDD\|225098
NC_006351.1\|WP_004187469.1\|3064913_3065309_-\|TraR/DksA-C4-type-zinc-finger-protein	unknown	unknown	gnl\|CDD\|224648
NC_006351.1\|WP_004196898.1\|3056540_3056981_+\|SRPBCC-family-protein	unknown	unknown	gnl\|CDD\|176863

Protein	Function_ID	Function_description	E-value
NC_006351.1\|WP_004552281.1\|3076640_3077294_+\|SagB/ThcOx-family-dehydrogenase	gnl\|CDD\|380318	cd02142, McbC_SagB-like_oxidoreductase, oxidase similar to the microcin B17 processing protein McbC. This family is the oxidase domain of NRPS (non-ribosomal peptide synthetase) and other systems that modify polypeptides by cyclizing a thioester to form a ring. These include EpoB, part of the epothilone biosynthesis pathway; TubD, part of the tubulysin biosynthesis pathway, MtsD, part of the myxothiozol biosynthesis pathway; IndC, part of the indigoidine biosynthesis pathway and TfxB, part of the trifitoxin processing pathway. All are FMN-dependent and oxidize the product of the cyclization of thioesters in short polypeptides.	4.23582e-20
NC_006351.1\|WP_004552282.1\|3078194_3079334_-\|porin	gnl\|CDD\|238208	cd00342, gram_neg_porins, Porins form aqueous channels for the diffusion of small hydrophillic molecules across the outer membrane. Individual 16-strand anti-parallel beta-barrels form a central pore, and trimerizes thru mainly hydrophobic interactions at the interface. Trimers are stabilized by hytrophillic clamping of Loop L2. Loop 3 bends into the pore, creating an elliptical constriction of about 7 x 11A, large enough to allow passage of a glucose molecule without steric hindrance. Removal of the C-terminal residue (usuallly F) destabilizes the trimer and removal of the 16th beta-sheet abolishes trimerization. Unlike typical membrane proteins, porins lack long hydrophobic stretches. Short turns are found at the smooth, periplasmic end, longer irregular loops are found at the rough, extracellular end. C-terminal residue forms salt bridge with N-terminus.	3.82792e-55
NC_006351.1\|WP_004530665.1\|3073433_3075266_+\|STAS-domain-containing-protein	gnl\|CDD\|223732	COG0659, SUL1, Sulfate permease and related transporters (MFS superfamily) [Inorganic ion transport and metabolism].	1.21999e-106
NC_006351.1\|WP_004205322.1\|3058718_3059654_+\|LysR-family-transcriptional-regulator	gnl\|CDD\|176109	cd08417, PBP2_Nitroaromatics_like, The C-terminal substrate binding domain of LysR-type transcriptional regulators that involved in the catabolism of nitroaromatic/naphthalene compounds and that of related regulators; contains the type 2 periplasmic binding fold. This CD includes the C-terminal substrate binding domain of LysR-type transcriptional regulators involved in the catabolism of dinitrotoluene and similar compounds, such as DntR, NahR, and LinR. The transcription of the genes encoding enzymes involved in such degradation is regulated and expression of these enzymes is enhanced by inducers, which are either an intermediate in the metabolic pathway or compounds to be degraded. Also included are related LysR-type regulators clustered together in phylogenetic trees, including NodD, ToxR, LeuO, SyrM, TdcA, and PnbR. This substrate-binding domain shows significant homology to the type 2 periplasmic binding proteins (PBP2), which are responsible for the uptake of a variety of substrates such as phosphate, sulfate, polysaccharides, lysine/arginine/ornithine, and histidine. The PBP2 bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap. After binding their specific ligand with high affinity, they can interact with a cognate membrane transport complex comprised of two integral membrane domains and two cytoplasmically located ATPase domains. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis.	7.67997e-62
NC_006351.1\|WP_004547986.1\|3079401_3081207_-\|fatty-acid--CoA-ligase	gnl\|CDD\|235730	PRK06187, PRK06187, long-chain-fatty-acid--CoA ligase; Validated.	0
NC_006351.1\|WP_004530666.1\|3072405_3073437_+\|nitroreductase-family-protein	gnl\|CDD\|236122	PRK07877, PRK07877, Rv1355c family protein.	7.9992e-31
NC_006351.1\|WP_004530669.1\|3066654_3067926_+\|polyhydroxyalkanoate-depolymerase	gnl\|CDD\|130908	TIGR01849, unnamed_protein_product, polyhydroxyalkanoate depolymerase, intracellular. This model represents an intracellular depolymerase for polyhydroxyalkanoate (PHA), a carbon and energy storing polyester that accumulates in granules in many bacterial species when carbon sources are abundant but other nutrients are limiting. This family is named for PHAs generally, rather than polyhydroxybutyrate (PHB) specificially as in Ralstonia eutropha H16, to avoid overcalling chemical specificity in other species. Note that this family lacks the classic GXSXG lipase motif and instead shows weak similarity to some [Fatty acid and phospholipid metabolism, Degradation].	4.16837e-113
NC_006351.1\|WP_004523292.1\|3054056_3055289_-\|3-methyl-2-oxobutanoate-dehydrogenase-(2-methylpropanoyl-transferring)-subunit-alpha	gnl\|CDD\|223997	COG1071, AcoA, Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit [Energy production and conversion].	5.32689e-143
NC_006351.1\|WP_011205761.1\|3062507_3064781_-\|FAD-dependent-oxidoreductase	gnl\|CDD\|369639	pfam07992, Pyr_redox_2, Pyridine nucleotide-disulphide oxidoreductase. This family includes both class I and class II oxidoreductases and also NADH oxidases and peroxidases. This domain is actually a small NADH binding domain within a larger FAD binding domain.	1.9178e-56
NC_006351.1\|WP_004547976.1\|3060319_3062218_+\|GMC-family-oxidoreductase	gnl\|CDD\|225186	COG2303, BetA, Choline dehydrogenase and related flavoproteins [Amino acid transport and metabolism].	5.29917e-35
NC_006351.1\|WP_004529492.1\|3068153_3069995_+\|ribonucleotide-reductase-like-protein	gnl\|CDD\|180772	PRK06948, PRK06948, ribonucleotide reductase-like protein; Provisional.	0
NC_006351.1\|WP_004530663.1\|3075737_3076187_-\|CBS-domain-containing-protein	gnl\|CDD\|341411	cd17775, CBS_pair_bact_arch, Two tandem repeats of the cystathionine beta-synthase (CBS pair) domains present in bacteria and archaea. The CBS domain, named after human CBS, is a small domain originally identified in cystathionine beta-synthase and is subsequently found in a wide range of different proteins. CBS domains usually occur in tandem repeats. They associate to form a so-called Bateman domain or a CBS pair based on crystallographic studies in bacteria. The CBS pair was used as a basis for this cd hierarchy since the human CBS proteins can adopt the typical core structure and form an intramolecular CBS pair. The interface between the two CBS domains forms a cleft that is a potential ligand binding site. The CBS pair coexists with a variety of other functional domains and this has been used to help in its classification here. It has been proposed that the CBS domain may play a regulatory role, although its exact function is unknown. Mutations of conserved residues within this domain are associated with a variety of human hereditary diseases, including congenital myotonia, idiopathic generalized epilepsy, hypercalciuric nephrolithiasis, and classic Bartter syndrome (CLC chloride channel family members), Wolff-Parkinson-White syndrome (gamma 2 subunit of AMP-activated protein kinase), retinitis pigmentosa (IMP dehydrogenase-1), and homocystinuria (cystathionine beta-synthase).	3.14402e-50
NC_006351.1\|WP_004200700.1\|3057305_3058421_-\|SRPBCC-family-protein	gnl\|CDD\|378454	pfam10604, Polyketide_cyc2, Polyketide cyclase / dehydrase and lipid transport. This family contains polyketide cylcases/dehydrases which are enzymes involved in polyketide synthesis. It also includes other proteins of the START superfamily.	2.16274e-11
NC_006351.1\|WP_004529498.1\|3077354_3077789_-\|Hsp20/alpha-crystallin-family-protein	gnl\|CDD\|223149	COG0071, IbpA, Molecular chaperone (small heat shock protein) [Posttranslational modification, protein turnover, chaperones].	9.00264e-33
NC_006351.1\|WP_004532595.1\|3070069_3071881_+\|bifunctional-aminoglycoside-phosphotransferase/ATP-binding-protein	gnl\|CDD\|225098	COG2187, COG2187, Uncharacterized protein conserved in bacteria [Function unknown].	3.75845e-75
NC_006351.1\|WP_004187469.1\|3064913_3065309_-\|TraR/DksA-C4-type-zinc-finger-protein	gnl\|CDD\|224648	COG1734, DksA, DnaK suppressor protein [Signal transduction mechanisms].	1.7869e-14
NC_006351.1\|WP_004196898.1\|3056540_3056981_+\|SRPBCC-family-protein	gnl\|CDD\|176863	cd07821, PYR_PYL_RCAR_like, Pyrabactin resistance 1 (PYR1), PYR1-like (PYL), regulatory component of abscisic acid receptors (RCARs), and related proteins. The PYR/PYL/RCAR-like family belongs to the SRPBCC (START/RHO_alpha_C/PITP/Bet_v1/CoxG/CalC) domain superfamily of proteins that bind hydrophobic ligands. SRPBCC domains have a deep hydrophobic ligand-binding pocket. PYR/PYL/RCAR plant proteins are receptors involved in signal transduction. They bind abscisic acid (ABA) and mediate its signaling. ABA is a vital plant hormone, which regulates plant growth, development, and response to environmental stresses. Upon binding ABA, these plant proteins interact with a type 2C protein phosphatase (PP2C), such as ABI1 and ABI2, and inhibit their activity. When ABA is bound, a loop (designated the gate/CL2 loop) closes over the ligand binding pocket, resulting in the weakening of the inactive PYL dimer and facilitating type 2C protein phosphatase binding. In the ABA:PYL1:ABI1 complex, the gate blocks substrate access to the phosphatase active site. A conserved Trp from PP2C inserts into PYL to lock the receptor in a closed formation. This group also contains Methylobacterium extorquens AM1 MxaD. The mxaD gene is located within the mxaFJGIR(S)ACKLDEHB cluster which encodes proteins involved in methanol oxidation. MxaD may participate in the periplasmic electron transport chain for oxidation of methanol. Mutants lacking MxaD exhibit a reduced growth on methanol, and a lower rate of respiration with methanol.	3.1145e-25

>NC_006351.1|WP_004187469.1|3064913_3065309_-|TraR/DksA-C4-type-zinc-finger-protein
MAAFDEHQLQVLGALLRACRQALQADVRAGERQRADEPYANLAGPAPDEGDEANADLFVDVDHALLGMKLAELRDVDAALQRIARRDYGCCADCGQPIAYERLLARPTALRCAPCQRAHERRFATQPRPSL
>NC_006351.1|WP_011205761.1|3062507_3064781_-|FAD-dependent-oxidoreductase
MREFDYLLVGGGIASVTAARTLRGEDASASIAILCGEPVLPYQRPPLSQEWLMGAVQPASITLHDAAFYVAQRIDIALGVRAEQLDRAKRIVRTSSGATFRYGKLLIATGASAKAPALPGFGLDGVHVLHTFAQAQALKDAAAHARRATVLGGGFLGVEIAATLQALGLQVTLVERAPGVMPSLRAPALGGHFEALCRARGIDVLTRCEVRRVLGAQCVEAVETSDGGTRPCDLFVAAVGVTPNCGWLDGSGLALGDGVEVDAFLQTADPDVFAAGDVAHFDDPIFGVRRRIEHWDNAVRQGRIAARNMLGHRLPYRDVSIFYGSVFGLSYNLLGYPVGATETIERGAFDEASYMQLYLADDVLRAAFTIDRPAVEIAALNDAIRLHVNVAAHKTKLSDPNYPLDKLPVQTILILQGGGALGAFECGAVKALEQHGVRPDVISAVSIGAFNGAIVASHPKGATKALEAFWRELSIALPLPYESQWREAWLSSYVLSFGVPNFLKPQWSQLGFDADRLRAKWTSFFDATAIEQLIARYVDFDSLGMSPTRLLIGAVDVETGEPRIFDSYVDRLSPAHVLASGSLPPGMPWTVVDGRPYWDGGVVSNSPLDLVIARCGQIGGRVFIVDLFSGSKALPTNLVEVMLRREEIAYMDRVRNDLRFEEYASDFRDLVDGILAHVDAPSANEIRQQPLYIRLMGNRAAIDIARITLNREGRLSFIEDYDFSSDAIAQLQQQGYDAALVALANGRSRRRRGRRRA
>NC_006351.1|WP_004547976.1|3060319_3062218_+|GMC-family-oxidoreductase
MLGATRSTLWGSRERPRIAAARAPGAAAIRMREEARECAGPRGAGRAPHRATAAGGKTGRRTVRAPSRARAGSNNQKVNRMKQQSYDYDYVVVGSGFGGSVSALRLSEKGYRVLVIEQGRRWTPENLPESTWNLSRWQWRPALGLRGFFSMRFFRHVVVLHGNAVGGGSITYANTLLVPPDKVWREGTWAGLEDWERVMPAHYATAKRMLGVVTNRRMDAADFRLKDMAKLIGVEKSFYPTEVGVFFGDDADAPGTRYADPYFGGAGPERTSCIGCGGCMVGCRHGAKNTLDRNYLYLAERLGAQVREQTKVVDVRPLDARADGAAGYAVEAVSLAAGARGAKSRLTCRGVVFAASSLGTQDLLMRLKEKGSLPRLSDALGKRVRTNAESLIGVRFPKSRVDLSKGVAIGSGIYIDEHTHIEATRYPSGSDTMGLLTTVLTRGAPGGLRVLVWLGALAKLVLTRPLSAWRMIDPRGFARETMIFLCMQTLEGHLTMRLKRRWFWPFSKQLATSGAKIPAYIPAANDFAQKAARALGGVPMTSLTEILLNVPMTAHCMGGAAMARDARDGVCDGRSRVFGYRNMYVCDGSVLGANLGVNPSLTITALAEHAMSHVPAAREQRWDSTAETPVAA
>NC_006351.1|WP_004548017.1|3059669_3060260_+|hypothetical-protein
MCRARGIGRQARGNATAPSPIAAAAIGARPRSAPRGPRISDAGRLAAARSAFAMHQERRKRNADRHGTHPYDADSRAAPREAPRFEHEPKKQRDAAQHEVDRDRAAREIRERIEHKARPDVRRAERPISQDVAQTPIGAAGAISPSTAHSIFLEIGLALAGRPIQVRRNRAPFTHGTPRRRPARGPTARTASPAPV
>NC_006351.1|WP_004205322.1|3058718_3059654_+|LysR-family-transcriptional-regulator
MIQNLRQLDLNLLLVFDALMQEQNLSRAAIRLHMSQPAVSNALTRLRQQLGEPLFTRTARGMTPTAQARTLYEPVRQALYLLQIGLGPQADFEPDTHHLFKLSMNDYGQTVLLPDLLAHIKSRAPNVMLSVQSDDAGSIPAQLTTGTLDLAIDYLHFDNPELCYEPLHEEHLVVIGRAGHPAFAGGLALRGYEESGHVSIQPRDRRGSPLEIVLGSARVRRVVHLQVPHYLTIPALVAKSDLLGTIPRRLAERFADVYALQIAPLPIDIAPIQVSLIWHRQQDAQPGLRWLREQVVLTHRAIIGCGEHAPA
>NC_006351.1|WP_004200700.1|3057305_3058421_-|SRPBCC-family-protein
MTQDVTVFRARYRASVHPRYNAWLHGGFVLAYGCAAIAFFLKDVARVSAVQWASVPAAFLLFNWLEFTVHRHVGHVKRRFGAMFYRRHTGDHHSFFANEQIAYREARDWRVILFPAWLIVVFSLGLFALHAVLGRFDANVAGLFASTMLGGYLLYECVHACEHLPDAHPLAKWPWIRQMRVLHRVHHRDALMRSCNFDVIWPLMDWLHGTLRWSEAPGADMSTRMRHEIDIACAGADVLAYASDASRWPEWHPSSLRVDGPAGSLAAGSRFDEDVRAAGRVDRLHWDVVRNEPGVMWQARAANTAGSLRILLTYECSGGPRGARFVRTLHYHSPNPLLRLANALVMRGRVERESAYSLTLLKRRLEAARDA
>NC_006351.1|WP_004196898.1|3056540_3056981_+|SRPBCC-family-protein
MKQQRIEIAEEFDAPVHQVFRFFSEHENLKSIFSPAKIRRISDGEPARNGVGSAREMRVPGAPPFVETVTAYQENELIEYRITRGSPLRDHLGVMRFVPIDERRTYFHYVITFEGKVPFVAPVVRHVLEGSIRRGLGKVATRRLWG
>NC_006351.1|WP_004196896.1|3056259_3056421_-|hypothetical-protein
MTMTLINVIVNRDDRRWTRSRIADAPRAGFERPAGGGRAVRTPSLGGENRMRV
>NC_006351.1|WP_076848180.1|3055788_3056145_-|hypothetical-protein
MRIAEALCARIVETRVDASAARPLPGSGAVTTARASTDISGLVRVAEAGGALPGRGSSSWAKVARAERRERRKPVDSGSERYRALGLSSCRDRTGRRPVASTAGERAACHAAGVPADR
>NC_006351.1|WP_004523292.1|3054056_3055289_-|3-methyl-2-oxobutanoate-dehydrogenase-(2-methylpropanoyl-transferring)-subunit-alpha
MSQYGPLRLHVPEPTGRPGCKTDFSYLRLSPAGKVRKPPIDVAPADTSDLAYGLVRVLDEHGRAVGPWAPDLDPDILRKGIRAMLKTRIFDARMQIAQRQKKISFYMQCLGEEAIAVAHTLALERGDMCFPTYRQQGILMVREYPLVDMMCQLMSNERDPLKGRQLPVMYSTRDAGFFSISGNLATQFIQAVGWAMASAIKGDTRIASAWIGDGATAEADFHTALTFAHVYRAPVILNVVNNQWAISTFQAIAGGEGATFAGRGVGCGIASLRVDGNDFLAVYAASRWAAERARRNLGPTLIEWVTYRAGPHSTSDDPTKYRPGDDWTNFPLGDPLERLKRHMIGIGVWSEQDHEDTKAALEAEVLAAQKEAERYGTLADEHVPNVASIFEDVYKEMPAHLRRQRQQLGV
>NC_006351.1|WP_004530669.1|3066654_3067926_+|polyhydroxyalkanoate-depolymerase
MLYAWLEAQREFFRACQPWAGAAQRAGAGAGARPAGWPTWGPMARAADAVPAPPPFAIASIEIDGAAVPVDECVVDDTPFCALRKFSRRLRGDAAARPAVFLCTPLAGHHAVMLRETVETILATRDVYVTDWRNARDVPPEAGAFGLDDYVCTLERFVAGAAGDGLHMMAVCQATVPALAAVALLAARDVHVTSVALLGGPVDTRSHPTLIDRFALEHDLDWFRRTAIDIVPPPYAGAGRRVYPGFIQHAAIIVAHPQRRASLESRYWAAWMTGDFAAAARCLREMNEYGAVLDMTERYFLDTIRVIFHERLLAQGRWSIGRRLVAPRRLTRTALCTIEGGRDDIAGAGQTHAAHALCDAVPDAVRERITEPDCDHYDLFLGPRWRRTIHPALDAFWTRAEAARAAAGEPRPTAERAERRIAH
>NC_006351.1|WP_004529492.1|3068153_3069995_+|ribonucleotide-reductase-like-protein
MRTINKRTRTIAHADSFVRMIGDMDDQPICDAVFADRYALPGEHSRAQACARVARALALAEPMATRSGAARRFYRNLLNGAFGAGRIMARAGAAPDQTMASCFVHPIRAPAALTRFHPNLDEALDEARLALAMGADIGYDFSAIPPAGARPDADHPDSPGVCAALDRFDRIGTQAGERDGRRRAQLAVLRCDHPDLLAFAAAKHRHAGRHARWTTLELAVAATDAFMQAVEQDLPWTLRHTAPPRDAPGGALPGADGAWTYASVPARHVWREIVSAARDGAGPGLVFVDAIDAADPLRGRERIDATSPCGAQPLPPYGSAMLGAIDLSRFVRNPFGAGGEPRFDFAAFDTAVRIEVRLLDNALDVTRWPLAAHARESYQKRRIGVGVTGLADMLAMMRLRYDSPAAREMARYIASDLRHHAYAASAELAAERGAYPLCDRHAHLDALRAGPPLPHAVCHAIERDGLRHSHLTSFAPVIGVSLAFGDHCSPGIEPARAWIEHRPVRAGAAGAPGMRAENHAHRLFRSLRGERAALPDYFATDADVAPGERLAMRVALQPYVDAGIDNTLTLANHYSLEEVNALLFAAWRAKLKSVAIRRADLARDAQPSDDDGV
>NC_006351.1|WP_004532595.1|3070069_3071881_+|bifunctional-aminoglycoside-phosphotransferase/ATP-binding-protein
MTTGAVAARRLPRRGTARGRRAPSRAFTIHGGDEMRRSRPPKPAKPAAVRRRPHGAARAHAIRGNGPQRRAVRERAARRLSRDIDAALRRASTYPHPAGPIVRIETHLSVVYLVGRFAYKRLKPFDFGFANFSELAARRRACEAELALNRPLAAPIYLAAGPLVRRARGLRLFGAGAAVDHVVRMRRFDERMLFSRLLARGALDAADIDAAATRLAAYHLHAPRDIPRRAYGSARELRRQLDDMLAPLERALGAALPASLRAWCVRRCDELAAHLDARRADGYVRACHGDLHLNNVVKRGRDALMFDCIDFDDALRWIDVINDLSFLLMDLHAHDRAALAHRLLNRWLDETGDFAGLAALPLYVAYRALVRALVATMRAGGDAAARAARIERARRYVDVAAHAARARRPCLLLCHGYSGSGKSVASRALADVSGAIRLSSDSERKRARPFAAVDARPLPASAYTPQQIDAQYERLRALARDVLRAGYTALVDATFLSHARRARFFALARELGVPVYVLDFHASRACLERRVDARAAARDDHSDAGAAVLATQRASADPLDADERARTIGFDTDVPLATLRSAGYWRPVLDALDAARVDAQATR
>NC_006351.1|WP_004530666.1|3072405_3073437_+|nitroreductase-family-protein
METSPLKTTTPEAIPPFDPSASVEDKLRLAIHYAILAPSSHNTQPWRFMVGDGSVMLCADRLRALSVVDPYDRELLISCGAALLNLRVALSRFGLAYVIDMFPSPSDPDVIALVRLDPHGYHDESLVPLFDAILERVTTRTPYANEAVPCDVQRALVDAGAAEGAEIACVDAPHALDEIAELIADADRLQFADPRFRRELANWVHPRRHDDGMPAFAAGVPALLDFATPVVASAIRTFDLGGGLAAMHHKLVDGSPLIVGISTASDDRDAWVAAGQALERVLLVAAAAGLTASYLNQPIEIDALRERLRPLLHVDAHPQLLLRIGRGPVVAHAPRRPLMDVVS
>NC_006351.1|WP_004530665.1|3073433_3075266_+|STAS-domain-containing-protein
MTERERAARGRNDARRGGGDSGGDDEAWRRWLPGIATLRTYRRAWLARDLYAGVALTAVLVPVGMSYAQAAGLPVIAGLNASIAALVGYAIFGPSRILVLGPDSALAALIAGAIAPLAHGEPAHAVALAAALALMSGGFCVLAGLLKLGFVTDLLSKPIQYGYLNGLALTLIASQLPSLLGTVPLGGTFVDQVASLAATVAQGRIDFASLALGGGCLAGIALLRRVAPAWPGMLIAVAGASIVAAWLGAAPDAGGAHAHVAYAHVANAHVALVGSLAGTLPPLGLPSISLADASRLIAGALAIAMVSVADISVLSHVFAQHDCSETDRNQELCALGAANLLAGMLRGCAVSSSASRTPVALAAGARTQLTSLVAAACIALLLVAPTLLARVPLAALAAVVVYSANALVDVRAIVRLYRVRRGECAVSVLCFAGVVLLGVVPGILLAVGLSLLSFVWRAWHPYDAVLGRVEGMHGYHDVSRHPGAALTRGLVAFRWDAPLFHANATIFRDHVRDAIAEADAPVRCVVIAAEPITDVDVTAADMLATLRDELAARRIALVFAEMKGPVKDRLRTYGLFEKIGADHFFPTVTDAIEHFTRMRKDVATARRARR
>NC_006351.1|WP_004530663.1|3075737_3076187_-|CBS-domain-containing-protein
MNAAEICTREVVACRRTDTVLDAAHLMRDRHVGDLIVVDDAGHAHAPVGMLTDRDIVLSLIAKDVDPAALFVGEIMSAPAAVVHEHDSLWTIAQRMRLTGVRRMPVVNADGALVGMVSVDDLLASVAALFDEIASISRRQIHFEEKARD
>NC_006351.1|WP_004552281.1|3076640_3077294_+|SagB/ThcOx-family-dehydrogenase
MSDPELLTYQPIAVALPGPAEAGAPAVIDLPPPDLGAGLPLMSALSLRASTREFSSAALAPTTLGELLWAADGVNRPTTGGRTAPSAHAFNEIDVYAALPDGVYRYDAALHRLLLKHAVDARNLTGYQDFVGAAPLDLIYVVRMSRLLSMPKPLRETFSAVAAGAIAQNVALYCASTGLGCVVRGWINHRLLAEALSLNEDELPILAQTVGKPAAHP
>NC_006351.1|WP_004529498.1|3077354_3077789_-|Hsp20/alpha-crystallin-family-protein
MSNVTRYDPFSLEPVSDLFQGLFRPLRGIADADDEKLASMKIDVTENDQAYAVKAELPGVDKNDINVQIDGNTVSISAKVERNKELKEGERVIRRERYSGEFARTFSLANELDRDAASAQYQDGVLSLTLPKKASSEKKKLTIG
>NC_006351.1|WP_004552282.1|3078194_3079334_-|porin
MGDVMNAKSIAAAALAVAQAGLAHAQSSVTLYGALDAGVLWQNTSAASFSPTAPNTGAVVRFKDGGVYSSLWGIKGTEDLGGGYRVNFRLQGAFDGGTGKFGLSDAPGAVAAFNQIATLGVSGPFGTFNAGRQIVPMIYAMADTDVRAARFFGSVLTAWLGLNTAAGWPGNSTNAPIGALYDSDALVYQSPAFGGASLALEYAPGGVPGGVQRGARASIVLKYASNALNLAAVYYNGHDTNPAPGASATGLDNNRFVYVGAQYKLKDVAVSASYGNGRNPARGDRVNLDMFAFGLGYRVSPFFRVSSGVYYLKDRNRSANRSTSIVLGADYELSKHTTLYAQGGRVDNRGTMAQMLAYGQPVAPGLATTAAMLGMRHSF
>NC_006351.1|WP_004547986.1|3079401_3081207_-|fatty-acid--CoA-ligase
MHATDQHSALNAAPSAYVYPLLVGQLLTHARGADAGRQIVYRGDVRHSYAQFRERIGRLAGALAALGVGADATVAVMDWDSHRYLESYFAIPMMGATLFTVNVRLSPRQIAHTLRDARASVVVAHADFLPLLEQVRDALGDSTCVIVACDGGAMPATSLPLAGEYERLVAAADPDYPFADFDENARAVLFYTTGTTGDPKGVCYSHRQIVLHALATAAALGAARDGQRLHRDDVYMPITPMFHVMAWGMPYIAVMLGLKIVLPGRYRAHALLDLRQAERVTFSHCVPAVLQMLLDEARLRACDLSGWKMIVGGSALPASLCRAARARHIDVFAGYGMSETGPVVALAQLRGTEGGVDVHADEDAGIDADVGAGIDVDTDVDADINANAGANASDSSVTTAAAHADDETAKRCAAGWPPPLVELRVVDAAMRDVPRDGRTPGEIVLRGPALALGYRGNPQASAALWAGGYLHTQDVAVMHGDGAIRIVDRIKDVIKTGGEWVSSLELEGLLNDIAGIRESAVVGVPDARWGERPAAVVVCERDAPLAAQDVRARLLEHVAANRISRYAVPECERIVFVDALPKTSVGKIDKKSLRRLVERID

You can click texts colored in the table to view more detailed information

Click the colored protein region to show detailed information

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

76173 : 141963

Ralstonia_phage(28.57%)

transposase,plate,holin

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_004544960.1\|76173_78369_+\|holin	phospholipase C, phosphocholine-specific	NA	NA	NA	NA
WP_004552613.1\|78944_79601_+	hypothetical protein	NA	NA	NA	NA
WP_023358215.1\|80154_81324_+\|transposase	IS30 family transposase	Q9MBM9	Staphylococcus_prophage	1.9e-32	30.1
WP_080002191.1\|82686_82941_+	SET domain-containing protein-lysine N-methyltransferase	NA	NA	NA	NA
WP_009939053.1\|82937_83957_-	AraC family transcriptional regulator	NA	NA	NA	NA
WP_004533753.1\|83976_84429_-	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_009939055.1\|84987_85833_+	ABC transporter permease	NA	NA	NA	NA
WP_023358505.1\|85819_86671_+	ABC transporter permease	NA	NA	NA	NA
WP_004552621.1\|86667_87699_+	extracellular solute-binding protein	NA	NA	NA	NA
WP_004528499.1\|88286_88592_+	H-NS histone family protein	NA	NA	NA	NA
WP_164927488.1\|88911_91692_+	type VI secretion system tip protein VgrG	A0A2H4JCD4	uncultured_Caudovirales_phage	8.9e-89	34.8
WP_011205330.1\|91705_93946_+	DUF3274 domain-containing protein	A0A077K801	Ralstonia_phage	3.1e-23	27.7
WP_045606150.1\|93964_95614_+	DUF2875 family protein	NA	NA	NA	NA
WP_004523722.1\|95623_95887_+	PAAR domain-containing protein	NA	NA	NA	NA
WP_004523721.1\|96301_96721_-	YjbQ family protein	NA	NA	NA	NA
WP_004523720.1\|96740_97067_-	thioredoxin family protein	NA	NA	NA	NA
WP_009922878.1\|97538_98231_+	hypothetical protein	NA	NA	NA	NA
WP_009939071.1\|98816_99536_-	DUF2244 domain-containing protein	NA	NA	NA	NA
WP_009939072.1\|99532_101128_-	cytochrome c oxidase subunit I	R9VX24	Flavobacterium_phage	3.2e-06	33.3
WP_162483434.1\|101425_102004_+	hypothetical protein	NA	NA	NA	NA
WP_004551158.1\|102279_103737_-	hypothetical protein	NA	NA	NA	NA
WP_153260193.1\|104081_104441_-	hypothetical protein	NA	NA	NA	NA
WP_011205333.1\|105289_107227_+	YadA-like family protein	A0A2C9CZG8	Yersinia_phage	4.5e-07	46.1
WP_004538932.1\|107293_108745_-	PhoPQ-regulated protein	NA	NA	NA	NA
WP_004523708.1\|108816_109032_+	hypothetical protein	NA	NA	NA	NA
WP_004549711.1\|109042_109597_-	hypothetical protein	NA	NA	NA	NA
WP_011205334.1\|110181_110727_+	type 1 fimbrial protein	NA	NA	NA	NA
WP_004523705.1\|110806_111529_+	fimbria/pilus periplasmic chaperone	NA	NA	NA	NA
WP_045606153.1\|111641_114386_+	fimbrial biogenesis outer membrane usher protein	NA	NA	NA	NA
WP_004529637.1\|114378_114951_+	type 1 fimbrial protein	NA	NA	NA	NA
WP_045606155.1\|114982_115672_+	DotU family type IV/VI secretion system protein	NA	NA	NA	NA
WP_011205338.1\|115674_117351_+	OmpA family protein	NA	NA	NA	NA
WP_004523700.1\|117728_118268_+	type VI secretion system contractile sheath small subunit	NA	NA	NA	NA
WP_004523699.1\|118301_119801_+	type VI secretion system contractile sheath large subunit	NA	NA	NA	NA
WP_004551170.1\|120000_120483_+	type VI secretion system tube protein Hcp	NA	NA	NA	NA
WP_004551171.1\|120610_121153_+	type VI secretion system lipoprotein TssJ	NA	NA	NA	NA
WP_004523698.1\|121158_122508_+\|plate	type VI secretion system baseplate subunit TssK	NA	NA	NA	NA
WP_004556024.1\|122504_123806_+	type VI secretion system protein TssL	NA	NA	NA	NA
WP_004551174.1\|123820_127729_+	type VI secretion system membrane subunit TssM	NA	NA	NA	NA
WP_004529647.1\|127918_128488_+	hypothetical protein	NA	NA	NA	NA
WP_045606158.1\|128585_131252_+	type VI secretion system tip protein VgrG	A0A077K8Q4	Ralstonia_phage	9.3e-35	26.0
WP_004523693.1\|131326_131596_+	PAAR domain-containing protein	NA	NA	NA	NA
WP_004556559.1\|131608_135061_+	RHS repeat protein	NA	NA	NA	NA
WP_011205341.1\|134953_136312_-	hypothetical protein	A0A292GJ55	Xanthomonas_phage	1.1e-108	44.8
WP_004536657.1\|136344_137373_-	fimbrial protein	NA	NA	NA	NA
WP_011205342.1\|137427_138498_-	type VI secretion system ImpA family N-terminal domain-containing protein	NA	NA	NA	NA
WP_011205343.1\|138516_139566_-\|plate	type VI secretion system baseplate subunit TssG	NA	NA	NA	NA
WP_004523687.1\|139562_141443_-\|plate	type VI secretion system baseplate subunit TssF	NA	NA	NA	NA
WP_004523686.1\|141444_141963_-\|plate	type VI secretion system baseplate subunit TssE	NA	NA	NA	NA

DBSCAN-SWA_2

532667 : 542526

Burkholderia_virus(58.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_004552315.1\|532667_533243_+	recombinase family protein	A0A219Y9V9	Aeromonas_phage	1.0e-23	39.6
WP_004552314.1\|533313_534429_-	DUF3396 domain-containing protein	E5E3X7	Burkholderia_phage	4.2e-175	80.1
WP_004552313.1\|534438_535173_-	VRR-NUC domain-containing protein	A4JWV4	Burkholderia_virus	5.1e-52	50.5
WP_004552312.1\|535169_535697_-	PAAR domain-containing protein	A4JWV5	Burkholderia_virus	2.8e-60	66.7
WP_009893919.1\|535976_536156_+	type II toxin-antitoxin system HicA family toxin	A0A0D4DC32	Acinetobacter_phage	1.2e-18	74.6
WP_004552310.1\|536200_536617_+	type II toxin-antitoxin system HicB family antitoxin	A0A0A8JBA5	Ralstonia_phage	7.2e-27	60.0
WP_004552308.1\|537045_537543_-	hypothetical protein	NA	NA	NA	NA
WP_004525420.1\|539213_539498_-	BrnA antitoxin family protein	K4NZP3	Burkholderia_phage	1.4e-10	50.0
WP_009939402.1\|539481_539655_-	BrnT family toxin	NA	NA	NA	NA
WP_004552388.1\|540322_540598_+	bacteriophage protein Gp49	Q6JIH4	Burkholderia_virus	2.3e-42	96.7
WP_009923452.1\|540607_540739_+	bacteriophage protein Gp48	Q8W6Q2	Burkholderia_virus	2.6e-15	97.7
WP_004552390.1\|540874_541096_+	hypothetical protein	NA	NA	NA	NA
WP_160469016.1\|541062_541362_+	hypothetical protein	Q6JIH9	Burkholderia_virus	1.0e-35	98.6
WP_038717720.1\|541536_542127_-	hypothetical protein	A4JX33	Burkholderia_virus	7.4e-102	97.4
WP_004537646.1\|542376_542526_+	bacteriophage protein Gp44	Q8W6Q6	Burkholderia_virus	3.3e-19	100.0

DBSCAN-SWA_3

695253 : 766775

Vibrio_phage(25.0%)

plate,holin

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_004525541.1\|695253_696021_-\|holin	phosphocholine cytidylyltransferase family protein	NA	NA	NA	NA
WP_004206084.1\|696059_697061_-	HpnL family protein	NA	NA	NA	NA
WP_004525542.1\|697057_697831_-	hypothetical protein	NA	NA	NA	NA
WP_004188272.1\|697827_698517_-	CDP-alcohol phosphatidyltransferase family protein	NA	NA	NA	NA
WP_004188420.1\|698881_700396_+	acetyl-CoA hydrolase/transferase family protein	NA	NA	NA	NA
WP_004525545.1\|702115_703054_+	type VI secretion system ImpA family N-terminal domain-containing protein	NA	NA	NA	NA
WP_004202234.1\|703087_703636_+	type VI secretion system contractile sheath small subunit	NA	NA	NA	NA
WP_004190846.1\|703638_705144_+	type VI secretion system contractile sheath large subunit	NA	NA	NA	NA
WP_004530039.1\|705287_705815_+	type VI secretion system tube protein Hcp	NA	NA	NA	NA
WP_004190879.1\|705894_706326_+	GPW/gp25 family protein	NA	NA	NA	NA
WP_004196180.1\|706339_708202_+\|plate	type VI secretion system baseplate subunit TssF	NA	NA	NA	NA
WP_004190851.1\|708198_709188_+\|plate	type VI secretion system baseplate subunit TssG	NA	NA	NA	NA
WP_004525547.1\|709190_712061_+	type VI secretion system ATPase TssH	A0A2I7REQ1	Vibrio_phage	2.4e-60	27.2
WP_004535244.1\|712051_714343_+	type VI secretion system tip protein VgrG	NA	NA	NA	NA
WP_004190563.1\|714508_716797_+	type VI secretion system tip protein VgrG	NA	NA	NA	NA
WP_004530041.1\|716800_719017_+	pentapeptide repeat-containing protein	NA	NA	NA	NA
WP_004525550.1\|719016_720087_+	pentapeptide repeat-containing protein	NA	NA	NA	NA
WP_004525551.1\|720089_720806_+	DUF3540 domain-containing protein	NA	NA	NA	NA
WP_004190606.1\|720848_721238_+	DUF4150 domain-containing protein	NA	NA	NA	NA
WP_004530042.1\|721243_721837_+	type VI secretion lipoprotein TssJ	NA	NA	NA	NA
WP_004525552.1\|721833_723195_+\|plate	type VI secretion system baseplate subunit TssK	NA	NA	NA	NA
WP_004525553.1\|723277_724936_+	DotU family type IV/VI secretion system protein	NA	NA	NA	NA
WP_004190265.1\|724932_728436_+	type VI secretion system membrane subunit TssM	NA	NA	NA	NA
WP_004190863.1\|728494_728854_+	hypothetical protein	NA	NA	NA	NA
WP_004190471.1\|728876_729302_+	hypothetical protein	NA	NA	NA	NA
WP_004536812.1\|729622_729898_+	hypothetical protein	NA	NA	NA	NA
WP_004528661.1\|730448_731348_+	alpha/beta hydrolase	NA	NA	NA	NA
WP_004530512.1\|731389_731680_-	hypothetical protein	NA	NA	NA	NA
WP_011205424.1\|731569_732889_+	glycosyltransferase	NA	NA	NA	NA
WP_004524286.1\|732885_734472_+	DHA2 family efflux MFS transporter permease subunit	NA	NA	NA	NA
WP_011205425.1\|734724_735720_+	glycosyltransferase family 2 protein	NA	NA	NA	NA
WP_004532079.1\|735845_736028_+	hypothetical protein	NA	NA	NA	NA
WP_004528656.1\|736024_737608_+	efflux transporter outer membrane subunit	NA	NA	NA	NA
WP_004186853.1\|738100_739354_+	efflux RND transporter periplasmic adaptor subunit	NA	NA	NA	NA
WP_009939521.1\|739866_741531_-	glycoside hydrolase family 32 protein	F8WPR5	Bacillus_phage	2.0e-56	31.4
WP_004186967.1\|741663_743148_-	glycoside hydrolase family 68 protein	NA	NA	NA	NA
WP_004530800.1\|743417_744434_+	substrate-binding domain-containing protein	NA	NA	NA	NA
WP_004523135.1\|744929_746129_+	formaldehyde dehydrogenase, glutathione-independent	A0A2K9L7I1	Tupanvirus	8.4e-12	27.2
WP_004198247.1\|746306_747332_-	GlxA family transcriptional regulator	NA	NA	NA	NA
WP_160457400.1\|747345_747630_+	hypothetical protein	NA	NA	NA	NA
WP_004523136.1\|747765_749040_+	serine hydroxymethyltransferase	A0A219Y950	Aeromonas_phage	5.3e-105	54.1
WP_004186989.1\|749112_750084_+	membrane dipeptidase	NA	NA	NA	NA
WP_004186987.1\|750234_750768_+	4-vinyl reductase	NA	NA	NA	NA
WP_004523137.1\|750828_752892_+	NADH:flavin oxidoreductase	NA	NA	NA	NA
WP_004186901.1\|752894_754820_+	(Fe-S)-binding protein	NA	NA	NA	NA
WP_004523138.1\|754824_755997_+	electron transfer flavoprotein subunit alpha/FixB family protein	NA	NA	NA	NA
WP_004535153.1\|755993_756779_+	electron transfer flavoprotein subunit beta	NA	NA	NA	NA
WP_004523139.1\|756803_758072_+	aromatic ring-hydroxylating dioxygenase subunit alpha	NA	NA	NA	NA
WP_004543120.1\|758092_759238_+	hybrid-cluster NAD(P)-dependent oxidoreductase	NA	NA	NA	NA
WP_004186918.1\|759347_760211_+	glycine betaine ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_004530057.1\|760391_762047_+	APC family permease	NA	NA	NA	NA
WP_004186920.1\|762133_763009_-	formyltetrahydrofolate deformylase	NA	NA	NA	NA
WP_004551409.1\|763152_764025_-	LysR family transcriptional regulator	NA	NA	NA	NA
WP_004186939.1\|764187_765741_+\|holin	choline-sulfatase	NA	NA	NA	NA
WP_004530058.1\|765737_766775_+\|holin	choline ABC transporter substrate-binding protein	NA	NA	NA	NA

DBSCAN-SWA_4

1391732 : 1495693

108

Burkholderia_virus(56.14%)

tail,protease,capsid,plate,transposase,terminase,head,portal,holin

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_004199327.1\|1391732_1392605_-\|protease	CPBP family intramembrane metalloprotease	NA	NA	NA	NA
WP_004199325.1\|1392816_1393521_-	fumarylacetoacetate hydrolase family protein	NA	NA	NA	NA
WP_004528273.1\|1393690_1394704_-	AraC family transcriptional regulator	NA	NA	NA	NA
WP_004202607.1\|1395401_1395545_+	hypothetical protein	NA	NA	NA	NA
WP_004199294.1\|1395560_1396082_+	sigma-70 family RNA polymerase sigma factor	A0A076YQ50	Rhizobium_phage	5.1e-06	27.1
WP_011205504.1\|1396078_1396903_+	anti-sigma factor	NA	NA	NA	NA
WP_004536762.1\|1396971_1397958_+	YceI family protein	NA	NA	NA	NA
WP_004528277.1\|1397997_1398357_+	lipoprotein	NA	NA	NA	NA
WP_004198480.1\|1398353_1398581_+	hypothetical protein	NA	NA	NA	NA
WP_004524116.1\|1398854_1399364_+	sigma-70 family RNA polymerase sigma factor	NA	NA	NA	NA
WP_011205506.1\|1399360_1400365_+	FecR family protein	NA	NA	NA	NA
WP_004556130.1\|1400491_1403158_+	TonB-dependent receptor	NA	NA	NA	NA
WP_011205508.1\|1403369_1404350_-	ABC transporter permease	NA	NA	NA	NA
WP_011205509.1\|1404342_1405428_-	ABC transporter permease	NA	NA	NA	NA
WP_011205510.1\|1405424_1407239_-	sugar ABC transporter ATP-binding protein	A0A2H4PQG7	Staphylococcus_phage	9.2e-10	25.2
WP_162486642.1\|1407235_1408246_-	sugar ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_004206353.1\|1408963_1409656_+	isoprenylcysteine carboxylmethyltransferase family protein	NA	NA	NA	NA
WP_011205513.1\|1410000_1410252_-	hypothetical protein	NA	NA	NA	NA
WP_004539126.1\|1410414_1411674_-	acyl-CoA dehydrogenase	NA	NA	NA	NA
WP_011205514.1\|1411893_1413363_-	MFS transporter	NA	NA	NA	NA
WP_038724247.1\|1413748_1413997_-	hypothetical protein	NA	NA	NA	NA
WP_004528289.1\|1414650_1414923_+	DUF4148 domain-containing protein	NA	NA	NA	NA
WP_009971776.1\|1415017_1416412_-	heavy metal sensor histidine kinase IrlS	W8CYF6	Bacillus_phage	2.0e-20	28.5
WP_004197868.1\|1416408_1417098_-	heavy metal response regulator transcription factor IrlR	W8CYM9	Bacillus_phage	1.7e-36	36.8
WP_004524131.1\|1417104_1420338_-	CusA/CzcA family heavy metal efflux RND transporter	NA	NA	NA	NA
WP_004551660.1\|1420383_1421853_-	efflux RND transporter periplasmic adaptor subunit	NA	NA	NA	NA
WP_028201463.1\|1421863_1423249_-	TolC family protein	NA	NA	NA	NA
WP_004197875.1\|1423484_1423769_-	hypothetical protein	NA	NA	NA	NA
WP_004524134.1\|1424166_1424307_-	bacteriophage protein	NA	NA	NA	NA
WP_004528293.1\|1424959_1425448_-	adenosine-specific kinase	NA	NA	NA	NA
WP_004197880.1\|1425779_1426265_+	YbaK/EbsC family protein	NA	NA	NA	NA
WP_009897097.1\|1426469_1426808_-	helix-turn-helix domain-containing protein	A4JWW9	Burkholderia_virus	5.4e-57	100.0
WP_004532752.1\|1427188_1427971_+	hypothetical protein	A4JWW8	Burkholderia_virus	6.7e-143	100.0
WP_009897093.1\|1428286_1428508_+	hypothetical protein	A4JWW6	Burkholderia_virus	1.6e-38	100.0
WP_009971783.1\|1428511_1428727_+	hypothetical protein	A4JWW5	Burkholderia_virus	2.1e-30	100.0
WP_004532784.1\|1428735_1428873_+	hypothetical protein	A4JWW4	Burkholderia_virus	2.8e-20	100.0
WP_009971784.1\|1429033_1429246_+	hypothetical protein	A4JWW3	Burkholderia_virus	1.1e-34	100.0
WP_009971785.1\|1429447_1430689_+	hypothetical protein	A4JWW2	Burkholderia_virus	1.7e-225	100.0
WP_006027270.1\|1430772_1430895_+	hypothetical protein	A4JWW1	Burkholderia_virus	7.7e-14	97.5
WP_009971786.1\|1430894_1432688_+	replication endonuclease	A4JWW0	Burkholderia_virus	0.0e+00	100.0
WP_009971787.1\|1432703_1432970_+	ogr/Delta-like zinc finger family protein	A4JWV9	Burkholderia_virus	3.1e-44	100.0
WP_004532731.1\|1432966_1433173_+	ogr/Delta-like zinc finger family protein	A4JWV8	Burkholderia_virus	8.7e-34	100.0
WP_004532770.1\|1433262_1433916_+	AAA family ATPase	A4JWV7	Burkholderia_virus	1.4e-114	100.0
WP_009897078.1\|1434149_1434272_+	CopG family transcriptional regulator	A4JWV6	Burkholderia_virus	5.9e-14	100.0
WP_004532793.1\|1434374_1434908_+	bacteriophage gp29 protein	A4JWV5	Burkholderia_virus	8.4e-97	100.0
WP_011205520.1\|1434904_1435642_+	VRR-NUC domain-containing protein	A4JWV4	Burkholderia_virus	5.9e-133	100.0
WP_029670743.1\|1435656_1436772_+	DUF3396 domain-containing protein	A4JWV3	Burkholderia_virus	3.7e-219	100.0
WP_024431052.1\|1437363_1437660_+	type II toxin-antitoxin system RelE/ParE family toxin	A4JWV2	Burkholderia_virus	1.1e-50	100.0
WP_009971793.1\|1437662_1438019_+	putative addiction module antidote protein	A4JWV1	Burkholderia_virus	1.5e-41	98.9
WP_011205524.1\|1438062_1439118_-\|portal	phage portal protein	A4JWQ2	Burkholderia_virus	7.5e-206	99.4
WP_009972550.1\|1439114_1440884_-\|terminase	terminase ATPase subunit family protein	K4NXI4	Burkholderia_phage	0.0e+00	99.2
WP_011205526.1\|1441027_1441837_+\|capsid	GPO family capsid scaffolding protein	A4JWU8	Burkholderia_virus	2.3e-146	98.9
WP_004532901.1\|1441870_1442884_+\|capsid	phage major capsid protein, P2 family	A4JWU7	Burkholderia_virus	5.5e-190	100.0
WP_004531049.1\|1442880_1443570_+\|terminase	terminase endonuclease subunit	K4NX86	Burkholderia_phage	2.5e-117	100.0
WP_004531050.1\|1443669_1444149_+\|head	head completion/stabilization protein	K4NZV5	Burkholderia_phage	5.8e-81	100.0
WP_009971798.1\|1444148_1444400_+	hypothetical protein	A4JWZ4	Burkholderia_virus	7.6e-40	100.0
WP_004524438.1\|1444396_1444603_+\|tail	tail protein X	K4PAW7	Burkholderia_phage	2.4e-31	100.0
WP_004524439.1\|1444617_1444962_+	membrane protein	K4NZQ3	Burkholderia_phage	2.9e-50	100.0
WP_004524440.1\|1444963_1445236_+\|holin	phage holin family protein	K4NX91	Burkholderia_phage	8.8e-42	100.0
WP_009941345.1\|1445232_1446045_+	DUF3380 domain-containing protein	A4JWZ0	Burkholderia_virus	1.2e-150	100.0
WP_009971799.1\|1446041_1446482_+	bacteriophage protein	K4NXJ2	Burkholderia_phage	3.8e-71	100.0
WP_004531054.1\|1446586_1447003_+\|tail	phage tail protein	A4JWT7	Burkholderia_virus	3.3e-72	100.0
WP_004531055.1\|1446999_1447467_+	phage virion morphogenesis protein	K4NZQ8	Burkholderia_phage	1.2e-78	100.0
WP_004534424.1\|1447620_1448124_+	hypothetical protein	K4NX96	Burkholderia_phage	2.8e-94	100.0
WP_045606069.1\|1448289_1449066_-	site-specific DNA-methyltransferase	K4NZW3	Burkholderia_phage	1.8e-148	99.2
WP_011205528.1\|1449239_1449920_+\|plate	phage baseplate assembly protein V	A4JWT3	Burkholderia_virus	5.3e-120	96.9
WP_004531058.1\|1449916_1450279_+\|plate	bacteriophage baseplate assembly protein W	K4PAX6	Burkholderia_phage	1.7e-61	100.0
WP_011205529.1\|1450275_1451181_+\|plate	baseplate assembly protein	K4NZR5	Burkholderia_phage	6.7e-163	99.7
WP_011205530.1\|1451173_1451728_+\|tail	phage tail protein I	A4JWT0	Burkholderia_virus	1.9e-99	99.5
WP_011205531.1\|1451738_1454102_+	bacteriophage protein gp17	A4JWY0	Burkholderia_virus	0.0e+00	99.1
WP_011205532.1\|1454118_1454790_+\|tail	tail assembly chaperone	A4JWS8	Burkholderia_virus	2.4e-112	96.4
WP_004531063.1\|1454845_1456018_+\|tail	phage tail sheath protein	Q45YG5	Burkholderia_virus	6.8e-224	100.0
WP_011205533.1\|1456033_1456543_+\|tail	phage major tail tube protein	K4NZR9	Burkholderia_phage	4.1e-93	99.4
WP_004531064.1\|1456600_1456945_+\|tail	phage tail assembly protein	K4NXA3	Burkholderia_phage	1.0e-55	100.0
WP_004552648.1\|1456953_1457067_+\|tail	GpE family phage tail protein	A0A089FGX3	Burkholderia_phage	5.4e-14	100.0
WP_045606072.1\|1457069_1460030_+	membrane protein	A4JWS3	Burkholderia_virus	0.0e+00	99.2
WP_009935906.1\|1460047_1460473_+\|tail	phage tail protein	A4JWS2	Burkholderia_virus	3.3e-72	99.3
WP_009971808.1\|1460472_1461573_+	phage late control D family protein	K4PAY4	Burkholderia_phage	5.8e-201	98.6
WP_172961430.1\|1461583_1462120_-\|transposase	IS21 family transposase	A4JWX0	Burkholderia_virus	8.2e-100	99.4
WP_009971809.1\|1462407_1463523_-	alanine dehydrogenase	NA	NA	NA	NA
WP_004524142.1\|1464247_1464577_-	H-NS histone family protein	NA	NA	NA	NA
WP_011205535.1\|1464590_1465142_-	ProQ/FinO family protein	NA	NA	NA	NA
WP_004542746.1\|1465653_1466418_+	fumarylacetoacetate hydrolase family protein	NA	NA	NA	NA
WP_004524145.1\|1466787_1467363_+	DUF2760 domain-containing protein	NA	NA	NA	NA
WP_004539133.1\|1467359_1469207_+	Hsp70 family protein	NA	NA	NA	NA
WP_011205537.1\|1469210_1472018_+	hsp70 family protein	A0A2H4UU19	Bodo_saltans_virus	3.0e-07	26.1
WP_004557566.1\|1472312_1473446_-	CapA family protein	S4VS02	Pandoravirus	9.5e-114	56.2
WP_162486637.1\|1473347_1473920_+	hypothetical protein	NA	NA	NA	NA
WP_004531797.1\|1474015_1474270_-	hypothetical protein	NA	NA	NA	NA
WP_004532969.1\|1474669_1475290_-	hypothetical protein	NA	NA	NA	NA
WP_004532967.1\|1475704_1476328_-	hypothetical protein	NA	NA	NA	NA
WP_011205538.1\|1476379_1478893_-	cation-translocating P-type ATPase	M1HM40	Paramecium_bursaria_Chlorella_virus	4.8e-57	27.9
WP_004528311.1\|1478990_1479470_-	carboxypeptidase regulatory-like domain-containing protein	NA	NA	NA	NA
WP_154585294.1\|1480038_1480509_-	hypothetical protein	NA	NA	NA	NA
WP_004531802.1\|1480558_1481305_+	class I SAM-dependent methyltransferase	NA	NA	NA	NA
WP_009981568.1\|1481558_1482989_-	thiamine pyridinylase	NA	NA	NA	NA
WP_004547623.1\|1483078_1483879_-	bifunctional hydroxymethylpyrimidine kinase/phosphomethylpyrimidine kinase	NA	NA	NA	NA
WP_004528317.1\|1484106_1484847_-	class I SAM-dependent methyltransferase	NA	NA	NA	NA
WP_004528318.1\|1484862_1485852_-	thymidylate synthase	NA	NA	NA	NA
WP_004528319.1\|1485853_1486309_-	hypothetical protein	NA	NA	NA	NA
WP_004528320.1\|1486305_1486782_-	NUDIX hydrolase	A0A0E3JJF3	Streptomyces_phage	1.6e-14	42.9
WP_004528321.1\|1486774_1486954_-	hypothetical protein	NA	NA	NA	NA
WP_004532962.1\|1487367_1488162_+	methyltransferase domain-containing protein	NA	NA	NA	NA
WP_004533011.1\|1488228_1489377_+	TauD/TfdA family dioxygenase	NA	NA	NA	NA
WP_004528326.1\|1489573_1490410_-	EamA family transporter	NA	NA	NA	NA
WP_004542846.1\|1491118_1492609_+	arginine-ornithine antiporter	NA	NA	NA	NA
WP_004532965.1\|1492917_1493526_+\|protease	rhomboid family intramembrane serine protease	NA	NA	NA	NA
WP_004528329.1\|1493692_1495693_-\|protease	ATP-dependent zinc metalloprotease FtsH	E5EQU5	Bathycoccus_sp._RCC1105_virus	6.4e-105	46.2

DBSCAN-SWA_5

2007997 : 2072041

Ostreococcus_tauri_virus(12.5%)

transposase,plate

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_009929993.1\|2007997_2009203_+\|transposase	IS110 family transposase	NA	NA	NA	NA
WP_004528767.1\|2009251_2011057_-	hypothetical protein	NA	NA	NA	NA
WP_004525366.1\|2011758_2012517_-	DeoR/GlpR transcriptional regulator	NA	NA	NA	NA
WP_045243639.1\|2013142_2014438_-	MFS transporter	NA	NA	NA	NA
WP_011205623.1\|2014765_2016235_-	mannitol dehydrogenase family protein	H8ZJP8	Ostreococcus_tauri_virus	1.9e-45	33.8
WP_004525363.1\|2016409_2017135_+	GntR family transcriptional regulator	NA	NA	NA	NA
WP_004525362.1\|2017156_2018365_+	D-galactonate dehydratase family protein	Q6A202	Oenococcus_phage	2.5e-43	29.2
WP_004198526.1\|2018413_2019445_+	Zn-dependent oxidoreductase	NA	NA	NA	NA
WP_004198523.1\|2020392_2020578_+	hypothetical protein	NA	NA	NA	NA
WP_004525361.1\|2020663_2021569_+	DMT family transporter	NA	NA	NA	NA
WP_004525360.1\|2021924_2022779_+	ammonia-dependent NAD(+) synthetase	G3MA24	Bacillus_virus	1.0e-59	47.4
WP_004545727.1\|2023033_2024068_-	TetR/AcrR family transcriptional regulator	NA	NA	NA	NA
WP_004546897.1\|2024179_2025397_+	Tm-1-like ATP-binding domain-containing protein	NA	NA	NA	NA
WP_004201924.1\|2025399_2026242_+	phosphoenolpyruvate hydrolase family protein	NA	NA	NA	NA
WP_004184911.1\|2026287_2026728_+	SRPBCC family protein	NA	NA	NA	NA
WP_004528780.1\|2027134_2028697_+	nitrite reductase, copper-containing	NA	NA	NA	NA
WP_004533161.1\|2028721_2029558_+	formylglycine-generating enzyme family protein	NA	NA	NA	NA
WP_004206326.1\|2029554_2030169_+	SCO family protein	NA	NA	NA	NA
WP_161935158.1\|2030571_2031063_+	hypothetical protein	NA	NA	NA	NA
WP_004206324.1\|2031207_2032233_+	N-acetylmuramoyl-L-alanine amidase	A0A076YN96	Rhizobium_phage	2.4e-07	27.1
WP_004525349.1\|2032360_2033761_+	autotransporter strand-loop-strand O-heptosyltransferase	NA	NA	NA	NA
WP_004557771.1\|2034695_2035334_+	YadA-like family protein	B0FIT1	Escherichia_phage	1.0e-08	37.0
WP_004553514.1\|2035413_2035791_+	hypothetical protein	NA	NA	NA	NA
WP_045606108.1\|2036033_2037986_-	type VI secretion system protein TssA	NA	NA	NA	NA
WP_004528788.1\|2037976_2038714_-	response regulator transcription factor	NA	NA	NA	NA
WP_011205628.1\|2038710_2040555_-	two-component system sensor kinase	NA	NA	NA	NA
WP_004530571.1\|2040814_2041309_+	type VI secretion system contractile sheath small subunit	NA	NA	NA	NA
WP_004200974.1\|2041305_2042832_+	type VI secretion system contractile sheath large subunit	NA	NA	NA	NA
WP_004525344.1\|2043051_2043561_+	type VI secretion system effector Hcp1	NA	NA	NA	NA
WP_004530572.1\|2043553_2044015_+\|plate	type VI secretion system baseplate subunit TssE	NA	NA	NA	NA
WP_004551874.1\|2044051_2045794_+\|plate	type VI secretion system baseplate subunit TssF	NA	NA	NA	NA
WP_004533373.1\|2045781_2046804_+\|plate	type VI secretion system baseplate subunit TssG	NA	NA	NA	NA
WP_011205629.1\|2046790_2049829_+	type VI secretion system ATPase TssH	A0A223W0B1	Agrobacterium_phage	9.1e-79	29.9
WP_009940775.1\|2049855_2052879_+	type VI secretion system tip protein VgrG	A0A077K8Q4	Ralstonia_phage	9.2e-23	24.8
WP_011205630.1\|2052904_2055547_+	pentapeptide repeat-containing protein	NA	NA	NA	NA
WP_004556233.1\|2055564_2056629_+	pentapeptide repeat-containing protein	NA	NA	NA	NA
WP_004551877.1\|2056625_2057378_+	DUF3540 domain-containing protein	NA	NA	NA	NA
WP_004200966.1\|2057406_2057799_+	DUF4150 domain-containing protein	NA	NA	NA	NA
WP_004533362.1\|2057808_2058606_+	type VI secretion system lipoprotein TssJ	NA	NA	NA	NA
WP_004536933.1\|2058638_2060036_+\|plate	type VI secretion system baseplate subunit TssK	NA	NA	NA	NA
WP_004551879.1\|2060032_2060698_+	DotU family type IV/VI secretion system protein	NA	NA	NA	NA
WP_181937968.1\|2060694_2064669_+	type VI secretion system membrane subunit TssM-5	NA	NA	NA	NA
WP_160447233.1\|2065385_2066609_+	Ig-like domain-containing protein	NA	NA	NA	NA
WP_004536825.1\|2066568_2066814_-	hypothetical protein	NA	NA	NA	NA
WP_009968906.1\|2067070_2067703_+	GTP cyclohydrolase I	A0A0P0HSD2	Acinetobacter_phage	7.6e-20	30.6
WP_004533180.1\|2068763_2070293_-	type III secretion system effector BopC	NA	NA	NA	NA
WP_004551886.1\|2070324_2070768_-	CesT family type III secretion system chaperone	NA	NA	NA	NA
WP_080003069.1\|2071435_2072041_+\|transposase	transposase	NA	NA	NA	NA

DBSCAN-SWA_6

2762408 : 2837551

Streptococcus_phage(14.29%)

transposase,plate

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_004529292.1\|2762408_2763137_+\|transposase	IS6 family transposase	A0A1X9I6C6	Streptococcus_phage	8.4e-23	31.7
WP_172644725.1\|2763533_2764790_+	amidohydrolase family protein	NA	NA	NA	NA
WP_004552566.1\|2764815_2765469_+	glutathione S-transferase	NA	NA	NA	NA
WP_004539275.1\|2765649_2766378_-\|transposase	IS6 family transposase	A0A1X9I6C6	Streptococcus_phage	1.2e-21	31.2
WP_004552499.1\|2766387_2766645_-	hypothetical protein	NA	NA	NA	NA
WP_023358425.1\|2766657_2766795_-	hypothetical protein	NA	NA	NA	NA
WP_009941129.1\|2767009_2768149_-	DUF746 domain-containing protein	NA	NA	NA	NA
WP_024429916.1\|2768148_2769909_-	ShlB/FhaC/HecB family hemolysin secretion/activation protein	NA	NA	NA	NA
WP_123874559.1\|2769902_2770421_-	hypothetical protein	NA	NA	NA	NA
WP_009941131.1\|2770429_2770759_-	hypothetical protein	NA	NA	NA	NA
WP_011205723.1\|2770765_2780077_-	hemagglutinin repeat-containing protein	NA	NA	NA	NA
WP_071811406.1\|2780228_2780426_-	hypothetical protein	NA	NA	NA	NA
WP_004533385.1\|2780426_2780690_-	putative Immunity protein 75	NA	NA	NA	NA
WP_038720255.1\|2781282_2785941_-	type IV secretion protein Rhs	A0A2H4JFP5	uncultured_Caudovirales_phage	8.3e-23	34.9
WP_004552171.1\|2785927_2787196_-	hypothetical protein	NA	NA	NA	NA
WP_004556461.1\|2787211_2789416_-	type VI secretion system tip protein VgrG	A0A077K8Q4	Ralstonia_phage	1.9e-41	27.5
WP_004525642.1\|2790627_2791848_-\|transposase	ISL3-like element ISBma1 family transposase	A9YX10	Burkholderia_phage	2.7e-239	99.8
WP_154585498.1\|2791879_2792146_-	hypothetical protein	NA	NA	NA	NA
WP_004540568.1\|2792730_2793330_-	dicarboxylate/amino acid:cation symporter	NA	NA	NA	NA
WP_004524853.1\|2793354_2793765_-	RidA family protein	NA	NA	NA	NA
WP_004524852.1\|2793879_2794989_-	asparaginase	NA	NA	NA	NA
WP_004552471.1\|2795169_2795802_+	PAS domain-containing protein	NA	NA	NA	NA
WP_004524850.1\|2796703_2797141_-	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_004552570.1\|2798377_2799451_-	porin	NA	NA	NA	NA
WP_004540527.1\|2799868_2801293_-	aldehyde dehydrogenase (NADP(+))	NA	NA	NA	NA
WP_011205727.1\|2801508_2802693_-	fumarylacetoacetate hydrolase family protein	NA	NA	NA	NA
WP_004524845.1\|2802703_2803591_-	aldose 1-epimerase	NA	NA	NA	NA
WP_009969404.1\|2803593_2804364_-	SDR family oxidoreductase	NA	NA	NA	NA
WP_004544686.1\|2804378_2805242_-	sugar ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	1.9e-13	25.4
WP_004524842.1\|2805238_2806207_-	ABC transporter permease	NA	NA	NA	NA
WP_004524841.1\|2806227_2807226_-	sugar ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_004524840.1\|2807263_2808466_-	mandelate racemase/muconate lactonizing enzyme family protein	Q6A202	Oenococcus_phage	6.9e-46	31.9
WP_004557914.1\|2808476_2809190_-	FadR family transcriptional regulator	NA	NA	NA	NA
WP_004544619.1\|2809321_2810212_+	SMP-30/gluconolactonase/LRE family protein	NA	NA	NA	NA
WP_004544660.1\|2810653_2811250_-	plasmid pRiA4b ORF-3 family protein	A0A2H4PDG5	Mycobacterium_phage	6.0e-27	38.1
WP_004529308.1\|2812869_2813217_-	IS66 family insertion sequence element accessory protein TnpB	A0A0P0ZBY2	Stx2-converting_phage	5.6e-41	73.8
WP_004555373.1\|2813213_2813621_-\|transposase	transposase	A0A0P0ZCV4	Stx2-converting_phage	4.9e-12	36.5
WP_011205729.1\|2814053_2816087_-	hypothetical protein	NA	NA	NA	NA
WP_004546333.1\|2816327_2818499_-	alpha-galactosidase	NA	NA	NA	NA
WP_004524829.1\|2818503_2819355_-	carbohydrate ABC transporter permease	NA	NA	NA	NA
WP_004524828.1\|2819355_2820279_-	sugar ABC transporter permease	NA	NA	NA	NA
WP_004552177.1\|2820341_2821583_-	extracellular solute-binding protein	NA	NA	NA	NA
WP_004524825.1\|2821618_2822863_-	ATP-binding cassette domain-containing protein	G9BWD6	Planktothrix_phage	7.1e-22	32.8
WP_009941141.1\|2822905_2823544_-	hypothetical protein	NA	NA	NA	NA
WP_004552181.1\|2825316_2826471_-	LacI family DNA-binding transcriptional regulator	NA	NA	NA	NA
WP_004548749.1\|2826776_2827034_+\|transposase	transposase	A0A1B0V7H9	Salmonella_phage	2.4e-09	60.4
WP_004524822.1\|2827810_2828551_+	hypothetical protein	NA	NA	NA	NA
WP_009941143.1\|2829282_2829711_-	DUF746 domain-containing protein	NA	NA	NA	NA
WP_045606131.1\|2829707_2830541_-	RHS repeat protein	NA	NA	NA	NA
WP_004539259.1\|2830500_2831211_-	hypothetical protein	NA	NA	NA	NA
WP_004203275.1\|2831226_2833431_-	type VI secretion system tip protein VgrG	A0A077K8Q4	Ralstonia_phage	9.6e-46	29.9
WP_004529320.1\|2833427_2836094_-	type VI secretion system ATPase TssH	K4FB40	Cronobacter_phage	1.8e-78	30.7
WP_004540225.1\|2836072_2837551_-\|plate	type VI secretion system baseplate subunit TssG	NA	NA	NA	NA

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

2. NC_006350

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Crispr_ID: NC_006350_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_006350_1

1499561-1499697

Orphan

Consensus_repeat	Method
CGCGTATGCGGCGAACGCCGGCGCGACAAGCGTTGCAGCGC	CRISPRCasFinder

1 spacers

The CRISPR arrays of NC_006350_1

>merge|NC_006350|1|1499561-1499697|CRISPRCasFinder
CGCGTATGCGGCGAACGCCGGCGCGACAAGCGTTGCAGCGCGGCGGACGAATGCCGTTCGCAAGTTCGCAGCGGTTCGCGCTGGAACGGCGTCTGCCGCGTATGCGGCGAACGCCGGTGCGACAAGCGTTGCAGCGC

>NC_006350|1|1|1499561-1499697|CRISPRCasFinder
CGCGTATGCGGCGAACGCCGGCGCGACAAGCGTTGCAGCGC	GGCGGACGAATGCCGTTCGCAAGTTCGCAGCGGTTCGCGCTGGAACGGCGTCTGC
CGCGTATGCGGCGAACGCCGGTGCGACAAGCGTTGCAGCGC

Protein	Signature genes	Signature genes Name	Protein_function
NC_006350.1\|WP_011204980.1\|1505094_1505919_+\|DUF1223-domain-containing-protein	unknown	unknown	gnl\|CDD\|369071
NC_006350.1\|WP_160974052.1\|1508126_1508339_+\|hypothetical-protein	unknown	unknown	unknown
NC_006350.1\|WP_004193488.1\|1496855_1497260_+\|aminoacyl-tRNA-hydrolase	unknown	unknown	gnl\|CDD\|181730
NC_006350.1\|WP_009936984.1\|1504643_1504934_+\|pentapeptide-MXKDX-repeat-protein	unknown	unknown	gnl\|CDD\|131998
NC_006350.1\|WP_004192878.1\|1483944_1484136_-\|hypothetical-protein	unknown	unknown	unknown
NC_006350.1\|WP_004550682.1\|1480967_1482023_-\|Fe(3+)-ABC-transporter-substrate-binding-protein	unknown	unknown	gnl\|CDD\|270260
NC_006350.1\|WP_004192284.1\|1508342_1509278_+\|EamA-family-transporter	unknown	unknown	gnl\|CDD\|183067
NC_006350.1\|WP_004521865.1\|1502062_1503994_-\|phosphomethylpyrimidine-synthase-ThiC	unknown	unknown	gnl\|CDD\|236451
NC_006350.1\|WP_011204976.1\|1487012_1490357_+\|exodeoxyribonuclease-V-subunit-gamma	unknown	unknown	gnl\|CDD\|335690
NC_006350.1\|WP_009936953.1\|1482262_1482442_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|320699
NC_006350.1\|WP_009936975.1\|1497669_1498953_-\|EAL-domain-containing-protein	unknown	unknown	gnl\|CDD\|238923
NC_006350.1\|WP_004193128.1\|1501626_1501839_-\|glycine-zipper-2TM-domain-containing-protein	unknown	unknown	gnl\|CDD\|182532
NC_006350.1\|WP_004191983.1\|1501150_1501375_-\|lipoprotein	unknown	unknown	unknown
NC_006350.1\|WP_011204978.1\|1494162_1496859_+\|AAA-family-ATPase	unknown	unknown	gnl\|CDD\|236783
NC_006350.1\|WP_004534567.1\|1484132_1486409_-\|FUSC-family-protein	unknown	unknown	gnl\|CDD\|372320
NC_006350.1\|WP_045606360.1\|1505909_1507082_+\|cytochrome-b/b6-domain-containing-protein	unknown	unknown	gnl\|CDD\|226602
NC_006350.1\|WP_009936979.1\|1499925_1500858_-\|DMT-family-transporter	unknown	unknown	gnl\|CDD\|273359
NC_006350.1\|WP_011204975.1\|1482583_1483948_-\|amino-acid-permease	unknown	unknown	gnl\|CDD\|182566
NC_006350.1\|WP_004526525.1\|1507097_1507889_+\|molybdopterin-dependent-oxidoreductase	unknown	unknown	gnl\|CDD\|239026
NC_006350.1\|WP_011204977.1\|1490353_1494166_+\|exodeoxyribonuclease-V-subunit-beta	unknown	unknown	gnl\|CDD\|236784

Protein	Function_ID	Function_description	E-value
NC_006350.1\|WP_011204980.1\|1505094_1505919_+\|DUF1223-domain-containing-protein	gnl\|CDD\|369071	pfam06764, DUF1223, Protein of unknown function (DUF1223). This family consists of several hypothetical proteins of around 250 residues in length which are found in both plants and bacteria. The function of this family is unknown. Structurally it lies in the Thioredoxin-like superfamily.	2.8519e-68
NC_006350.1\|WP_004193488.1\|1496855_1497260_+\|aminoacyl-tRNA-hydrolase	gnl\|CDD\|181730	PRK09256, PRK09256, aminoacyl-tRNA hydrolase.	3.43394e-65
NC_006350.1\|WP_009936984.1\|1504643_1504934_+\|pentapeptide-MXKDX-repeat-protein	gnl\|CDD\|131998	TIGR02953, conserved_hypothetical_protein, pentapeptide MXKDX repeat protein. Members of this protein family are small bacterial proteins, each with an N-terminal signal sequence followed by up to 11 imperfect repeats of a pentapeptide. The pentapeptide repeat usually follows the form Met-Xaa-Lys-Asp-Xaa.	1.67172e-05
NC_006350.1\|WP_004550682.1\|1480967_1482023_-\|Fe(3+)-ABC-transporter-substrate-binding-protein	gnl\|CDD\|270260	cd13542, PBP2_FutA1_ilke, Substrate binding domain of ferric iron-binding protein, a member of the type 2 periplasmic binding fold superfamily. FutA1 is the periplasmic component of an ABC-type iron transporter and serves as the primary receptor in Synerchosystis species. The periplasmic iron binding protein plays an essential role in the iron uptake pathway of Gram-negative pathogenic bacteria and is critical for survival of these pathogens within the host. After binding iron with high affinity, FutA1 interact with a cognate membrane transport complex comprised of two integral membrane domains and two cytoplasmically located ATPase. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis. The iron- and thiamine-binding proteins belong to the PBPI2 superfamily of periplasmic binding proteins that differ in size and ligand specificity, but have similar tertiary structures consisting of two globular subdomains connected by a flexible hinge. They have been shown to bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap.	9.86009e-154
NC_006350.1\|WP_004192284.1\|1508342_1509278_+\|EamA-family-transporter	gnl\|CDD\|183067	PRK11272, PRK11272, putative DMT superfamily transporter inner membrane protein; Provisional.	4.46808e-57
NC_006350.1\|WP_045606360.1\|1505909_1507082_+\|cytochrome-b/b6-domain-containing-protein	gnl\|CDD\|226602	COG4117, COG4117, Thiosulfate reductase cytochrome B subunit (membrane anchoring protein) [Energy production and conversion].	1.21242e-56
NC_006350.1\|WP_004521865.1\|1502062_1503994_-\|phosphomethylpyrimidine-synthase-ThiC	gnl\|CDD\|236451	PRK09284, PRK09284, thiamine biosynthesis protein ThiC; Provisional.	0
NC_006350.1\|WP_011204976.1\|1487012_1490357_+\|exodeoxyribonuclease-V-subunit-gamma	gnl\|CDD\|335690	pfam04257, Exonuc_V_gamma, Exodeoxyribonuclease V, gamma subunit. The Exodeoxyribonuclease V enzyme is a multi-subunit enzyme comprised of the proteins RecB, RecC (this family) and RecD. This enzyme plays an important role in homologous genetic recombination, repair of double strand DNA breaks resistance to UV irradiation and chemical DNA-damage. The enzyme (EC:3.1.11.5) catalyzes ssDNA or dsDNA-dependent ATP hydrolysis, hydrolysis of ssDNA or dsDNA and unwinding of dsDNA. This family consists of two AAA domains.	0
NC_006350.1\|WP_009936953.1\|1482262_1482442_+\|hypothetical-protein	gnl\|CDD\|320699	cd07340, M48B_Htpx_like, Peptidase M48 subfamily B HtpX-like membrane-bound metallopeptidase. This HtpX family of peptidase M48 subfamily B includes uncharacterized HtpX homologs and consists of proteins smaller than Ste24p, with homology restricted to the C-terminal half of Ste24p. HtpX expression is controlled by the Cpx stress response system, which senses abnormal membrane proteins. HtpX participates in the proteolytic quality control of these misfolded proteins by undergoing self-degradation and collaborating with FtsH, a membrane-bound and ATP-dependent protease, to eliminate them. HtpX, a zinc metalloprotease with an active site motif HEXXH, has an FtsH-like topology, and is capable of introducing endoproteolytic cleavages into SecY (also an FtsH substrate). However, HtpX does not have an ATPase activity and will only act against cytoplasmic regions of a target membrane protein. Thus, HtpX and FtsH have overlapping and/or complementary functions, which are especially important at high temperature; in E. coli and Xylella fastidiosa, HtpX is heat-inducible, while in Streptococcus gordonii it is not.	0.00619391
NC_006350.1\|WP_004193128.1\|1501626_1501839_-\|glycine-zipper-2TM-domain-containing-protein	gnl\|CDD\|182532	PRK10540, PRK10540, osmotically-inducible lipoprotein OsmB.	5.81885e-06
NC_006350.1\|WP_011204978.1\|1494162_1496859_+\|AAA-family-ATPase	gnl\|CDD\|236783	PRK10875, recD, exodeoxyribonuclease V subunit alpha.	1.43449e-72
NC_006350.1\|WP_004534567.1\|1484132_1486409_-\|FUSC-family-protein	gnl\|CDD\|372320	pfam12805, FUSC-like, FUSC-like inner membrane protein yccS. This family has similarities to the fusaric acid resistance protein family. The proteins are lodged in the inner membrane.	5.92051e-82
NC_006350.1\|WP_009936975.1\|1497669_1498953_-\|EAL-domain-containing-protein	gnl\|CDD\|238923	cd01948, EAL, EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2). The EAL domain has been shown to stimulate degradation of a second messenger, cyclic di-GMP, and is a good candidate for a diguanylate phosphodiesterase function. Together with the GGDEF domain, EAL might be involved in regulating cell surface adhesiveness in bacteria.	1.30559e-53
NC_006350.1\|WP_009936979.1\|1499925_1500858_-\|DMT-family-transporter	gnl\|CDD\|273359	TIGR00950, Uncharacterized_inner_membrane_transporter_YicL, Carboxylate/Amino Acid/Amine Transporter. [Transport and binding proteins, Amino acids, peptides and amines].	2.06538e-12
NC_006350.1\|WP_011204975.1\|1482583_1483948_-\|amino-acid-permease	gnl\|CDD\|182566	PRK10580, proY, putative proline-specific permease; Provisional.	0
NC_006350.1\|WP_004526525.1\|1507097_1507889_+\|molybdopterin-dependent-oxidoreductase	gnl\|CDD\|239026	cd02108, bact_SO_family_Moco, bacterial subgroup of the sulfite oxidase (SO) family of molybdopterin binding domains. This domain is found in a variety of oxidoreductases. Common features of all known members of this family, like sulfite oxidase and nitrite reductase, are that they contain one single pterin cofactor and part of the coordination of the metal (Mo) is a cysteine ligand of the protein and that they catalyze the transfer of an oxygen to or from a lone pair of electrons on the substrate. The specific function of this subgroup is unknown.	1.21624e-90
NC_006350.1\|WP_011204977.1\|1490353_1494166_+\|exodeoxyribonuclease-V-subunit-beta	gnl\|CDD\|236784	PRK10876, recB, exonuclease V subunit beta; Provisional.	0

>NC_006350.1|WP_009936975.1|1497669_1498953_-|EAL-domain-containing-protein
MPKTQGFSPESLISQFTRCDAGWCVRYHDVTLASAFQPVISITHKRVVGYEALARATDANGAPISPDTLFARAQARGETILLDRLTRCLHVANFAAQDTGACWLFLNVLPQMFDAGIAPGAFIEALCAHFALPPTRVVLEVIEQPSRNEVALARTIDMIQHGDFLIAVDDFGTGFSNFDRIWQIKPDIVKLDRSILERSLAASDAHRIIHHLVTMLHHAGTMVLAEGVENEDALQILMDADVDFVQGFCFGRPAPSLEHARRAAPARIEAAWRRFAERTKARCGDVVHPGFDTIERIMLTGAADYAQTRNLRDAAQRLLTSPIVRRVFVAEANGEQVEPSVTIETPEAPSATARRLAPLLPELHCNWSRRAYFQRAIAAPGRVALMGPHFSLTDGRDCYTAAVAIHLGTTLKVFCVDFDFSSYGDGR
>NC_006350.1|WP_004193488.1|1496855_1497260_+|aminoacyl-tRNA-hydrolase
MTLRYAFSPDEVELTAVRAQGAGGQNVNKVSSAIHLRFDIRASSLPDDVKARLFARADQRITREGVIVIKAQEYRTQEKNRAAALARLDTLIRSAGVTPRKRVATRPTRASKERRLAEKGRRSEVKSGRGRVVE
>NC_006350.1|WP_011204978.1|1494162_1496859_+|AAA-family-ATPase
MSVVDERFAWTGGLADRLPEPADFGLALAEGFARRIGMLSRRVGASAAAARWAARAAFAASRATAAGHVCVALRALAQRYDEPYDDVRAALAASGVTAFDGIVRGGECPLVVDRDGRLYLARYFEYETRLANALVERSRCGGAPACGADALSPDALGERLVRYFGPQKERGVDWQRVAALIALTGRVTIVSGGPGTGKTTTVVGVIACLLDAHPELRIALAAPTGKAAQRMQEALHARAGSLPAELAARLPRTSCTLHRLLGGGPGGRFAHHRDNPLPYDLVVVDEASMIDVALAAHLLDALAPNARLVLLGDKDQLAAVEAGAVFAELSARPAFSPATCATIARALGVGEAEFVAALPDGFVVQAVGAERVADARAAAADMDVAARGTAGAAAAAARATAAAAARMTTAAAAARGGAPESAAQRAPAPHAGRRGGGRASNRTVDDAQGSLFAFDDDAFGVGTSCGEPGAGAQGAGRRDGGAPSLDEPHAGRRDGGASPGVAHSRRDAFDARARSGPADVSDLENAARAYAPAGAAGPADSPADASFVEPAAWIEADELAWLDNAVFSFSEGASANAEADGRRSAAATATDAGARTAPPVAREATAPTPRETARSDGSAVAPLTDCVVWLERNYRFGLDSPIGRLSLAIRRGAVQDALDALSTQDDAAARFSDDGGATLSAATVEQLARGFAGYAAALRDALATPEPDALPLFDVLNRFRVLCATRTGARGAEEVNARMAAEVRRAVRVPLALGAHWFAGRPVMVTRNDYALGLFNGDIGIALPGARGALRVWFRGADGRARAVSPAALPPHDTAFALTVHKSQGSEFDDAALILPASFNRVLSRELVYTAITRARARVQVIGSRAVLALAIATRTARDSGLAARIADALRARQEGAR
>NC_006350.1|WP_011204977.1|1490353_1494166_+|exodeoxyribonuclease-V-subunit-beta
MSHVAPSGPSASELDVFACPLDGVNQIEASAGTGKTWNICALYVRLLLEKDLGADEILVVTFTKAATAELHERIRARLAQLAHALDTGDDGGDPFIARLFETTLAPERGLDPQTAAKRVRRALRAFDQAAIHTIHAFCQRALQEAPFAAAMPFAFEMEADDGALRFELAADFWRTRVEPVAAAYPAFAEWLVEYGAGPAALDAQLARRLKKPLARLRWDGLHAADDGAESAARAHFDTAAAIWRDERGVLGTLLADAQPSLNQRSHKPEAVSEALDAWARYFEQASAVAALPRAALKLTQSALEKATKKGGATPRHAFFDVAQALEAAVAALEAAQRARWLSLVEQWLDAAPAELAQRKRTRRVVSFDDLLANLYRALDAHPWLRETLRARYPAALIDEFQDTDPLQFAIFDTIFAPAGPLFLVGDPKQAIYSFRAADLHTYLAARARASARYTLAVNQRSTPAIVGACNRVFGANPRAFVLDGLDYEPVRAGSRVRAPLVDATDPLAGAGDFRIWTLPAGDDVLTKRDAQRHAAHACAAEIARLMRGARERAVTLGGEPLAASGIAVLVQTHRQGSLVKRVLAAWGIGSVELAQASVFATIDAEQLERVLAAIDAPGDLRRLRSALASDWFGLDAAALWRLEQGDAEQDGIDAAARGASGNGGGARAASAGAPAPSPADADAMGWVERFSRYRLLWRERGFAVMWRTLAGELRIAERLMAGADGERRVTDVNHLAELTQARASAQPGIAPTLRWLAAQRLEGGGDDAQLRLESDRNLVQIVTVHKSKGLEYAIVFCPFLNDGGLREPAGSGLPDAREYHDESGCAVLHYGCDDEAAERASREAVREQAAERARLVYVALTRAVYRCYLVAGTYQSSRSTKEARRSVLNWLVAGAGRDFDAWLKEPPEDAELAERWQALAGGPVTLGALPVPAHREPLAAGHDAQATRAARRATRGLRDAWRIASFSSLASAIARDESGIARAADDEMRPDHDALAAALGADALEPPDAAAAIAPAPAAAPRELAEDDILAFPRGAAAGECLHRLLELSNFADASTWPPAALRALHERPVEAELALAERLPAMMTRLVADLAATELVPGMRLAALDPARRLTEMEFLFPAPALDFNALRRLLAAHGYPDVALEAGTLAGFVKGFIDMIVEHDGRFWIVDWKSNHLGTTPEAYGERALDAAMAHHAYHLQALLYMVALHRYLRVRMHGYDYDAHIAGYLYVFVRGVRPDWRNGGASAGVHARRPARALIEALDALMREGDA
>NC_006350.1|WP_011204976.1|1487012_1490357_+|exodeoxyribonuclease-V-subunit-gamma
MLHLFYSNRHETLADALLDDLAFASDGAGPWAAQQVIVPSAALRRRLELDLAKRHGVCANVRFSYLAQWLWAQIGEVLTVPAHSPFAPDRLVWRCYRLLSDHGAAPWRASPRLAAYLAAADAPMRHELAHRIATVFDHYLTYRPEWLAQWQDGESIFALEGAPRHGGEAARDDEAWQAALWRALLAELSDSGMPPAHRFLREARAFDPDVIARARAKWPDAVSVFALPTMPPLHIALLRELSRWIDVRIYALSPCREFWFDIVTAARAESLDAADRLDYQEVGHPLLAEWGRQTQAQLHMLHELTESAAASDASRYADNPAPTWLARVQNAILDLQPEAALGEPPAERGVEVHVCHSLARQLEVLHDRLLAWFDADPNLAPSDVLVAMPDLATAGPLIDAVFGTPAGADAARIPYWITGLPPSQANPVARVLLDWLALPERDVGAPELVEWLRADAVAARYGIDATALETVQTWLAASGARRGLAPDAAEPPNPAVPAPRHTFADALTRLFLGYAMPDGAAPVSTWLPIAGAEGGEAELLGRLARFTDDLDGFARRIARDLTPQGWGDVFADALARFFDSGPAFADALSGVRDALDAMLAAMAEGAAGAALPAAVVRAGLAAALDDPARGGVPWGGVTFSSLTSLRGLPYRIVCLIGMDDGVLPSLARADEFDLMAVFAKLGDRQRRDDERNLFLDLLLAARERLLIAYTGRSIRDNAPLPPAALVDELLDHLAAASAGPDAPPDAVDAARRAFVIEHPLQPFSAEYFAPGGALFTYDASRATLARLLAEGARAQARPFFAAPLPAEPEQPVAFADFERFWRHPARSLLRARLGIVLLDAQAELVDTEPFELDYAGSDALAERVLPLLIETADAAAFEHALRVADASPEVPGGATGAVRRDHALDALAQLAGNVRRALADGATRVPFAFDVAPAWPAASDARWFGEHDAALAAAATREPLRLHGALARLTAAGQVIYRYARPGARDYLAAWLAHLVYCAIDPGGPRRTLWFGSGDTFEFAPVAAPLEQLAPLAALFRAGRRMPLAFFPRSAWALVSESESKAAGVWINDRVAGEADDASLALAWRGANPSLDEPFGALAHLVFDPLVEHLRRAS
>NC_006350.1|WP_004534567.1|1484132_1486409_-|FUSC-family-protein
MRYSVEIRKFFYSQYFFGGLRIALGVSLPAVLSLAVLHDRELGFTIATGALGACVVDMPGPLKYKHNEMLACSVIGFFSALATGLATPNIFALWLTIVPLTFALSLIVVYGNRWPQISFATLFMMVMTLEEKFTPLQALVNASWILAGGLWYTYWATIVSRWQARRIEQQALAESLFACASYLLARADFYDLDADLDECYRNLVARQITAVETQETARDIVLRNLPKLRRGKLDPGRTMMFNLFINSVDLHEMFVGAHTDYPLVRSTFGGSDLMIFYRDLIRKAAADLEEIGFAVLENRLPHSRISVKAELRAIEYEIELMRKKQFAATHPEAYAAVLATFRRIWSATRLIDKMRRNLSGSADAQRTELKIDKALTRFLQKRRMSPLLIFSNLNMGSPSLRHALRVTIAVAVGFWLGRLLPLTNAYWIVMTSIIILKPGYSLTKQRNAQRIVGTLIGCAASLALIYTVHEPHVLIAIMFGSMVMSYSLLLFNYAASVVFTSSYVLLLFHLLAPGNMRIIGERAIDTVVGCMIAIAASRLFPYWEYRAIGKLVADALATTRKYFEATWRAGRGKAAPAVPAADGAAAVPAVAAVVDAVAPGLDGDYQYRLARKNVHIAFANLGQAFQRMMLEPKAHQKFVPELNDLLVQTHVLGAQITAAAPLLRHACEQGNPPALERGMAAVREHLEQAEAGVPPPANQAETSKQLTRELDSMVVDAERSDAGADLAHDLKVLAHQCKQMLASSLLIRKDASVIRLPE
>NC_006350.1|WP_004192878.1|1483944_1484136_-|hypothetical-protein
MSRPPPPFLSTVSRRARTQGFPDYCPRASIGMIYPAPSCLYNFSSASAGPHRPADDTNHSETR
>NC_006350.1|WP_011204975.1|1482583_1483948_-|amino-acid-permease
MKNLQRHLSARHIRFLALGSAIGTGLFYGSASAIRLAGPAVILAYIVGGAAVYMVMRALGEMAVREPVPGSFGHYATENLGPFAGFVTGWTYTLEMVIVAIADITAFGIYMGFWFPHVPQWIWVLAIVAIICGLNLCHVKVFGELEFWLSIVKVGAIVAMIGGGAAILFTGMRLGSGGAPSLANLWSHGGFLPNGVGGLVASLSVVIFAYGGIEVIGMSAGEAKEPERAIPRAINAVPMRILLFYVLTMIVLMSIFPWTGVGANGSPFVQIFSALGVRSAAEILNLVVISAAISAINSDIFGAGRMMYAMALQGQAPRALAAMSARGVPWVTVLVMAGALLVGVVLNYLMPKDVFLMVAASATFATVWVWLMILLSQIAMRRRLGAAEVAALKFKVPFWPVGPALTIAFMAFVIAMLGYFDDTRVALFVGAAWLAILALVFYTRIRPRLAAVAR
>NC_006350.1|WP_009936953.1|1482262_1482442_+|hypothetical-protein
MNDPRSKKNPVFGVAMLIVVVIALVIGTILYNAISQKHEYDEAHPHAASAASAASAQHG
>NC_006350.1|WP_004550682.1|1480967_1482023_-|Fe(3+)-ABC-transporter-substrate-binding-protein
MFVKQARPLLRTLLRPLAFAFALAAVAPAAHAANEVNLYTTREPKLIQPLVDAFTKQSGIAVNTVFVKDGLLERVKAEGARSPADVLMTVDIGNLLDLVDGGLTQPVRSASLDGAIPANLRGAGGNWYALSLRDRVLYVDKNMQLDAITYESLADPKWKGKVCIRSGQHPYNTALVAAMIAHDGEAAAEQWLRGVKANLARKATGGDRDVARDILGGICDIGLANAYYAGHMKHAQPGTDARKWGDAIKVVRPTFANAKSGGTHVNVSGAAVAKHAPNRDNAVKLLEYLASPPAQALYAQANYEYPVRAGVALDPVIAGFGPLKVDPLPLVEIAKYRKRASQLVDKVGFDN
>NC_006350.1|WP_009936979.1|1499925_1500858_-|DMT-family-transporter
MNLKNALLLIVLAALWGASFLFIRVGVAEFGVAPLMALRVGIGALFLVALMLTRYAPRELIALLRQHAWPLFVVGLLNSAAPFCLFAFAELTLSAGVTSVINATTPLWGALVAYLWLKDSLSLPRALGLVIGFAGVLTLVWDQVFSPHGANPASPATAALAAAAALGATLLYGIAANFTKRKLTGVDPLVSATGSMVGATILLLPFALATWPAAPVSAHAWGSVLALGIACTGVAYFIFFHLIAHIGPARAITVTFVIPVFGILWGALFLGERVSFAMLEGCVIVLLGTALATGAIRRIPGVRPQRNETA
>NC_006350.1|WP_004191983.1|1501150_1501375_-|lipoprotein
MNKTLVAAALASVALAGCYYPYGYYPASGYYAAPVQTAPVYVAPAYPAYYYPAPSLSLNFGYWSGGGRGYWRHH
>NC_006350.1|WP_004193128.1|1501626_1501839_-|glycine-zipper-2TM-domain-containing-protein
MKSIRRIGVCAMLIATMASLSACDTMTTRQRNAAIGAGIGGVAGAAIGGNALSTIGGAAAGGLVGSQVGK
>NC_006350.1|WP_004521865.1|1502062_1503994_-|phosphomethylpyrimidine-synthase-ThiC
MNANPKFLSADARVDAAAVAPLPNSRKVYVTGSQPDIRVPMREITQADTPTSFGGEKNPPIYVYDTSGPYTDPDAKIDIRAGLPALRQRWIDARGDTETLAGLTSDYGRERAADPATAELRFPGLHRHPRRAKAGKNVTQMHYARQGIITPEMEYIAIRENQRRAEYLESLKASGPNGAKLAAMMGRQHAGQAFGAAAFGANAPAEITPEFVRDEVARGRAIIPANINHPETEPMIIGRNFLVKINANIGNSAVTSSIGEEVDKMTWAIRWGGDTVMDLSTGKHIHETREWIIRNSPVPIGTVPIYQALEKVNGKAEDLTWEIFRDTLIEQAEQGVDYFTIHAGVRLQYVPLTANRMTGIVSRGGSIMAKWCLAHHKESFLYEHFEEICEIMKAYDVSFSLGDGLRPGSIYDANDEAQLGELKTLGELTQIAWKHDVQVMIEGPGHVPMQLIKENMDLQLDWCKEAPFYTLGPLTTDIAPGYDHITSGIGAAMIGWFGTAMLCYVTPKEHLGLPNKDDVKEGIITYKLAAHAADLAKGHPGAQVRDNALSKARFEFRWQDQFNLGLDPDKAREFHDETLPKDSAKVAHFCSMCGPHFCSMKITQDVREFAAQQGVSENDALKKGMEVKAVEFVKSGSEIYHRQ
>NC_006350.1|WP_009936984.1|1504643_1504934_+|pentapeptide-MXKDX-repeat-protein
MKRNLIAFACVAGFALAAPFAHAQNDAMSKDGMGMSKDAMSKGAMSGDAMSKDAMSKDRMGKRHDHMAKGGMKAGPMSKDAMKEPMSSDKMSPMSN
>NC_006350.1|WP_011204980.1|1505094_1505919_+|DUF1223-domain-containing-protein
MSTDMSISFSVSLRAVAAALSLAAAGAAQAAADGACMARSPDGRQALVELYTSEGCSSCPPADDWLARLAARRAALRVVPLALHVDYWDGLGWADRFAQHRFTERQHALAARGGGRFVYTPEVAVDGRELRDWRDADAFGRRVVATAAAPARVGIALAAKRRAGALDVALSVTPRVGAPRALDAYLALYENGVESQVSAGENRGATLRHERVVRQWIGPLAATADAHASLDVRRALPLPANLRAADAARYGVAAFVEDPATGDVLQALDLPLCG
>NC_006350.1|WP_045606360.1|1505909_1507082_+|cytochrome-b/b6-domain-containing-protein
MRLNDARAIDQRTRVSPMSATPTTSASTTAMAGARASGAADAPARAPTGADVDAGATAWADATANATANATTDPTIDATADATTDAMANVTTDAATRVTANPPIHETANVPASTAAAATTEAVAGARAGAALDAAHPGATQTMSQTMSQTMAQTMAQTMAQTMTQTMTQAGTEAASPAGTDAAASGTCITRATRARRPIHPLWVRASHWLNALAAVTMALSGWRIYNASPIYAGFVFPRGATLGGWLGGALQWHFAAMWLLFFNGVFYLTMGVATGRFTRKLLPLSASGVARDLRDALRGRLSHDDLSVYNALQRAAYVAAIADLALLVLSGLVIWKSVQFPLLREWLGGYDRARVVHFWAMAFLVAFFVVHVAMAALVPRSLLAMLRGH
>NC_006350.1|WP_004526525.1|1507097_1507889_+|molybdopterin-dependent-oxidoreductase
MSENDRKKRENDIARIDRASLLIDVRKSLALPSRRLFGKRMLTLGGLAMLTGCTLRDDASVDDFLEKVSRANDRVQAWLFGPTRLAPTYAEADITRPFPFNAFYGIDEVPRVDADGFRLAVSGLVTGQRSWSLPALYALPHAEQITRHICVEGWSAIGRWGGTPFREFLRRVGADTSAKYVGFKCADDYYESIDMATALHPQTLLAFEYDGKRLPPEYGFPMKLRMPTKLGYKNPKHIVEIFVTNAYPGGYWVDQGYNWFGGS
>NC_006350.1|WP_160974052.1|1508126_1508339_+|hypothetical-protein
MLTKCGRHAAHVIIRVRLRVRSSPSVMFAAARSDLSFRTPPFPVIPVFPAPLAGGRIARRSTARRFTRAG
>NC_006350.1|WP_004192284.1|1508342_1509278_+|EamA-family-transporter
MTPFDRFLAFVARHPPRLPQSRSGRVALALVFIYFAWGSTYLALHVALESFPPLLLSGLRNLLAGVGLFVFAMRRRPVRPTLVEIRNAALVGTMLVTMSSGLIALGMRTVSSGSAAVMVATVPLFATVIASVAGRRVTGGEWGAVALGMVGIVVLNSGGPSSPGSTLGSITVLAGALFWAGGAHLAARLALPHDLFLSTALQIGLGGAASTCIAWVLGERIGHVAWVPGAAFVYLMLAGTMAAYVAYGYLIRHTSPIIASSCMYVNPVVAVALGALLLGEPVTAATVIATIAILGSVGLSFVFDPARRRAQ

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Crispr_ID: NC_006350_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_006350_2

2052199-2052297

Orphan

Consensus_repeat	Method
CGCGCGCCGCCGCCGCGCCCCCG	CRISPRCasFinder

1 spacers

The CRISPR arrays of NC_006350_2

>merge|NC_006350|2|2052199-2052297|CRISPRCasFinder
CGTGCGGCCGCGCGCCGCCGCCGCGCCCCCGGAACACGGATATCGCCGCGGCGCGCGCCCGGCGAATCCATTCGCGCGCCGTCCGCCGCGCCCCCGCCG

>NC_006350|2|2|2052199-2052297|CRISPRCasFinder
CGTGCGGCCGCGCGCCGCCGCCG	CGCCCCCGGAACACGGATATCGCCGCGGCGCGCGCCCGGCGAATCCATTCGCG
CGCCGTCCGCCGCGCCCCCGCCG

Protein	Signature genes	Signature genes Name	Protein_function
NC_006350.1\|WP_004526983.1\|2055326_2056583_+\|arginine-deiminase	unknown	unknown	gnl\|CDD\|234949
NC_006350.1\|WP_004192711.1\|2050379_2051318_+\|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|224050
NC_006350.1\|WP_004192820.1\|2042399_2042687_+\|hypothetical-protein	unknown	unknown	unknown
NC_006350.1\|WP_004521539.1\|2058927_2059722_-\|SDR-family-oxidoreductase	unknown	unknown	gnl\|CDD\|181762
NC_006350.1\|WP_004192049.1\|2060265_2061186_+\|LysR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|176163
NC_006350.1\|WP_004193559.1\|2051314_2052133_+\|ABC-transporter-permease	unknown	unknown	gnl\|CDD\|224095
NC_006350.1\|WP_004531280.1\|2045351_2046755_+\|MFS-transporter	unknown	unknown	gnl\|CDD\|182502
NC_006350.1\|WP_004531281.1\|2040268_2042011_-\|methyl-accepting-chemotaxis-citrate-transducer	unknown	unknown	gnl\|CDD\|185001
NC_006350.1\|WP_004193082.1\|2043298_2045275_+\|acyl-CoA-synthetase	unknown	unknown	gnl\|CDD\|236043
NC_006350.1\|WP_004526980.1\|2061470_2062175_+\|glutathione-S-transferase-N-terminal-domain-containing-protein	unknown	unknown	gnl\|CDD\|183298
NC_006350.1\|WP_004550481.1\|2048227_2049166_+\|ABC-transporter-substrate-binding-protein	unknown	unknown	gnl\|CDD\|270334
NC_006350.1\|WP_004550484.1\|2057746_2058685_+\|carbamate-kinase	unknown	unknown	gnl\|CDD\|183466
NC_006350.1\|WP_009937387.1\|2047095_2047866_-\|class-I-SAM-dependent-methyltransferase	unknown	unknown	gnl\|CDD\|379312
NC_006350.1\|WP_004521536.1\|2056647_2057658_+\|ornithine-carbamoyltransferase	unknown	unknown	gnl\|CDD\|179366
NC_006350.1\|WP_004521531.1\|2042723_2042912_-\|DUF3562-domain-containing-protein	unknown	unknown	gnl\|CDD\|378806
NC_006350.1\|WP_004192541.1\|2053848_2055309_+\|arginine-ornithine-antiporter	unknown	unknown	gnl\|CDD\|163522
NC_006350.1\|WP_004521540.1\|2059718_2060168_-\|heme-binding-protein	unknown	unknown	gnl\|CDD\|377163
NC_006350.1\|WP_011205058.1\|2062730_2063270_+\|winged-helix-turn-helix-transcriptional-regulator	unknown	unknown	gnl\|CDD\|224759
NC_006350.1\|WP_004521532.1\|2049162_2050383_+\|ABC-transporter-permease	unknown	unknown	gnl\|CDD\|224095
NC_006350.1\|WP_004198172.1\|2053355_2053688_+\|hypothetical-protein	unknown	unknown	unknown

Protein	Function_ID	Function_description	E-value
NC_006350.1\|WP_004192049.1\|2060265_2061186_+\|LysR-family-transcriptional-regulator	gnl\|CDD\|176163	cd08474, PBP2_CrgA_like_5, The C-terminal substrate binding domain of an uncharacterized LysR-type transcriptional regulator CrgA-like, contains the type 2 periplasmic binding fold. This CD represents the substrate binding domain of an uncharacterized LysR-type transcriptional regulator (LTTR) CrgA-like 5. The LTTRs are acting as both auto-repressors and activators of target promoters, controlling operons involved in a wide variety of cellular processes such as amino acid biosynthesis, CO2 fixation, antibiotic resistance, degradation of aromatic compounds, nodule formation of nitrogen-fixing bacteria, and synthesis of virulence factors, to name a few. In contrast to the tetrameric form of other LTTRs, CrgA from Neisseria meningitides assembles into an octameric ring, which can bind up to four 63-bp DNA oligonucleotides. Phylogenetic cluster analysis showed that the CrgA-like regulators form a subclass of the LTTRs that function as octamers. The CrgA is an auto-repressor of its own gene and activates the expression of the mdaB gene which coding for an NADPH-quinone reductase and that its action is increased by MBL (alpha-methylene-gamma-butyrolactone), an inducer of NADPH-quinone oxidoreductase. The structural topology of this substrate-binding domain is most similar to that of the type 2 periplasmic binding proteins (PBP2), which are responsible for the uptake of a variety of substrates such as phosphate, sulfate, polysaccharides, lysine/arginine/ornithine, and histidine. The PBP2 bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap. After binding their specific ligand with high affinity, they can interact with a cognate membrane transport complex comprised of two integral membrane domains and two cytoplasmically located ATPase domains. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis.	3.82358e-81
NC_006350.1\|WP_004526983.1\|2055326_2056583_+\|arginine-deiminase	gnl\|CDD\|234949	PRK01388, PRK01388, arginine deiminase; Provisional.	0
NC_006350.1\|WP_004550484.1\|2057746_2058685_+\|carbamate-kinase	gnl\|CDD\|183466	PRK12354, PRK12354, carbamate kinase; Reviewed.	0
NC_006350.1\|WP_004521539.1\|2058927_2059722_-\|SDR-family-oxidoreductase	gnl\|CDD\|181762	PRK09291, PRK09291, SDR family oxidoreductase.	7.48497e-166
NC_006350.1\|WP_004193559.1\|2051314_2052133_+\|ABC-transporter-permease	gnl\|CDD\|224095	COG1174, OpuBB, ABC-type proline/glycine betaine transport systems, permease component [Amino acid transport and metabolism].	2.10949e-62
NC_006350.1\|WP_004531280.1\|2045351_2046755_+\|MFS-transporter	gnl\|CDD\|182502	PRK10504, PRK10504, putative transporter; Provisional.	3.48527e-74
NC_006350.1\|WP_004531281.1\|2040268_2042011_-\|methyl-accepting-chemotaxis-citrate-transducer	gnl\|CDD\|185001	PRK15041, PRK15041, methyl-accepting chemotaxis protein.	5.16065e-108
NC_006350.1\|WP_004193082.1\|2043298_2045275_+\|acyl-CoA-synthetase	gnl\|CDD\|236043	PRK07529, PRK07529, AMP-binding domain protein; Validated.	0
NC_006350.1\|WP_004526980.1\|2061470_2062175_+\|glutathione-S-transferase-N-terminal-domain-containing-protein	gnl\|CDD\|183298	PRK11752, PRK11752, putative S-transferase; Provisional.	1.49489e-70
NC_006350.1\|WP_004550481.1\|2048227_2049166_+\|ABC-transporter-substrate-binding-protein	gnl\|CDD\|270334	cd13616, PBP2_OsmF, Substrate-binding domain OsmF of an osmoregulated ABC-type transporter; the type 2 periplasmic-binding protein fold. Osmoprotectant binding lipoprotein OsmF of an ABC transporter (YehZYXW) from Escherichia coli is predicted to be involved in uptake of compatible solutes such as choline, L-proline and glycine betaine, but the relative substrate preference is not known. To counteract the efflux of water, microorganisms accumulate the compatible solutes for a sustained adjustment to high osmolarity surroundings. OsmF belongs to the type 2 periplasmic binding fold protein superfamily (PBP2). The PBP2 proteins are typically comprised of two globular subdomains connected by a flexible hinge and bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap.	8.9029e-151
NC_006350.1\|WP_009937387.1\|2047095_2047866_-\|class-I-SAM-dependent-methyltransferase	gnl\|CDD\|379312	pfam13649, Methyltransf_25, Methyltransferase domain. This family appears to be a methyltransferase domain.	1.46549e-22
NC_006350.1\|WP_004521536.1\|2056647_2057658_+\|ornithine-carbamoyltransferase	gnl\|CDD\|179366	PRK02102, PRK02102, ornithine carbamoyltransferase; Validated.	0
NC_006350.1\|WP_004521531.1\|2042723_2042912_-\|DUF3562-domain-containing-protein	gnl\|CDD\|378806	pfam12085, DUF3562, Protein of unknown function (DUF3562). This family of proteins is functionally uncharacterized. This protein is found in bacteria. Proteins in this family are typically between 62 to 84 amino acids in length. This protein has two completely conserved residues (A and Y) that may be functionally important.	6.05092e-18
NC_006350.1\|WP_004192541.1\|2053848_2055309_+\|arginine-ornithine-antiporter	gnl\|CDD\|163522	TIGR03810, arginine-ornithine_antiporter, arginine-ornithine antiporter. Members of this protein family are the arginine/ornithine antiporter, ArcD. This exchanger of ornithine for arginine occurs in a system with arginine deiminase, ornithine carbamoyltransferase, and carbamate kinase, with together turn arginine to ornithine with the generation of ATP and release of CO2. [Transport and binding proteins, Amino acids, peptides and amines].	0
NC_006350.1\|WP_004521540.1\|2059718_2060168_-\|heme-binding-protein	gnl\|CDD\|377163	pfam03928, Haem_degrading, Haem-degrading. Haem_bdg is a bacterial protein that is up-regulated in response to haemin- and peroxide-based oxidative stress. It interacts with the SenS/SenR two-component signal transduction system. Iron binds to surface-exposed lysine residues of an octomeric assembly of the protein.	3.97468e-27
NC_006350.1\|WP_011205058.1\|2062730_2063270_+\|winged-helix-turn-helix-transcriptional-regulator	gnl\|CDD\|224759	COG1846, MarR, Transcriptional regulators [Transcription].	3.76003e-14
NC_006350.1\|WP_004521532.1\|2049162_2050383_+\|ABC-transporter-permease	gnl\|CDD\|224095	COG1174, OpuBB, ABC-type proline/glycine betaine transport systems, permease component [Amino acid transport and metabolism].	1.56661e-59
NC_006350.1\|WP_004192711.1\|2050379_2051318_+\|ABC-transporter-ATP-binding-protein	gnl\|CDD\|224050	COG1125, OpuBA, ABC-type proline/glycine betaine transport systems, ATPase components [Amino acid transport and metabolism].	1.75989e-144

>NC_006350.1|WP_004193559.1|2051314_2052133_+|ABC-transporter-permease
MTRAIKAASAATEAGALGAAGRRAPVMLARVAALAALAVMLARPGWLEPLFAPFADNGAPAIYRRASLLDLTLSHLAIVGAASAAGAVVALAAGIFVTRRAGAEFLPVARSVVHIGQTFPPVAVLALAVPAVGFGVKPVLIALILYGLLPIFESTIAGLQDVPAGAVDAARAMGMSALQRLAWIELPLAFPVVLNGIRLAVVINLGTATIGSTVAAKGLGDVIIAGLQTSNTAFVLQGGLVVALLAVLIYDALGVIGRWLAPASAAREEGGA
>NC_006350.1|WP_004192711.1|2050379_2051318_+|ABC-transporter-ATP-binding-protein
MIEIERVSRLFGDLAAVDDVSLAVARGTVTALVGASGSGKSTLLRMINRLIAPTSGTIRVDGVDTASVPAETLRRGIGYVIQGHGLFPHWTVARNVATVPRLLGWRAARVDARVRELLELFELDYDTYARKLPHQLSGGQQQRVGVARALAAEPAILLMDEPFGALDPIIRGKAQDDLVALQRRLGITVVIVTHDIDEALRLGDQIAVMDAGRILQAGSPAEILGRPQPGVVERLVAGLDRPLRLLALTRVDALAEPGAAPGEPISGALTLRDAISELLWRGARALPVSSADGAAARRITLDAIVAQAKRPA
>NC_006350.1|WP_004521532.1|2049162_2050383_+|ABC-transporter-permease
MTPRTAGGAAAPAPAPRPRAMPAWAARVDKVGVLIAALVAYAAFVLPFVTLRANRIAAGAELAPAAVFPALHAYALDALWAAGALFALVRSRAAWRAAVGVGLVFALGVAIGAAPAHLVTPDTPLARVSPAAGAWLLLFAFAVLIADALARIALAPAMRLVALAAASAALAAFIHGGFWDGLSVMQEYAVRADTFRNEAIRHLALVAGSVAAAVALGVPLGIGCTRSAALRGALLPLLNVVQTIPSIALYGLLMAPLAILAARVPLAARLGVSGIGVAPALIALFLYALLPIVSSVVVGFAQVPAAVVEAALAMGMTGRERLVAIELPLALPVVLSGVRIVLVQNIGLTAVAALIGGGGFGTFIFQGIGQSATDLVLLGALPTIALALVTAVLFEAATDLAKGARR
>NC_006350.1|WP_004550481.1|2048227_2049166_+|ABC-transporter-substrate-binding-protein
MKVPRFSRTLRAAAAALAVSLCAAAPGARAAGAVIVASKIDTEGNLLGNVISQVLKAHGIAVVDKIGLGATPIVRRALTTGEIDIYPEYTGNAAFFFNKADDPAWKNAAQGYALARQLDYAANRIVWLAPAPANNTWGVAVLNSIAQAQHLKTFSDFGKWVAAGGKVKLAASAEFVNSASALPSFEKAYGFKLKPEQMLVLSGGDTAATIKAAAQQTDGVNAAMVYGTDGGIAATGLAVLDDDKHVQPVYAPTPIIREAVLNAHPQIADYLKPVFASLDLKTLQALNARIQINGEPAAGVAASYLKAKGFVK
>NC_006350.1|WP_009937387.1|2047095_2047866_-|class-I-SAM-dependent-methyltransferase
MSSDPHTAPQSAPQNIYDDASFFEGYRTLRQGDTGLNGALESPAMKGLLPNLAGLHVLDLGCGFGDFARYARAHGAASVTAVDVSSRMLEEARARTDDGAVTYLQRSIETYHAATRAFDLVVSSLTLHYVEDYAGVVARIYDALRSNGRFVFSVEHPICTAYPHGWVRGDDGHKQHWPVDRYRQEGRRDTRWFVDGVVKYHRTVETYVNTLLKAGFTLTHLGEPAPVPDALAVRPDLEAECRRPPVLFLAAVRAGN
>NC_006350.1|WP_004531280.1|2045351_2046755_+|MFS-transporter
MRAGDFRVTAAVVASALFMQNLDSTVVATALPSMARELGVNVVFLSSAITSYLVALTVFIPVSGWIAERFGAKRVFIAAIAIFTAASVMCAAANGLATLVAARILQGAGGALMVPVGRLILYRGVSRHEMLAATTWLTMPALVGPLLGPPLGGFLTDALSWRAVFWINVPVGVAGAALAARLVPASAGERRAPADARGMLLVGAALAALMLGVETAGRDVLPAGAPALCLGAGVALGGLTIRHCRRVAHPVVDLSLLGIPTFHAATIAGSLFRAGAGALPFLVPLTLQVGFGASASRSGAITLASALGSLVMRPMTHAALHRAPMRTVLIAGSVSFAAVLAACATLSPAWPDAAVFALLLVGGLSRSLSFASLGALVFSDVPSERLSAATSFQGTAQQLMRAVGVAVAAGALHLAMLIGGRGQASRTDFAGAFAAIALVVLASVPMFAALPADAGEGLAGPARRPRP
>NC_006350.1|WP_004193082.1|2043298_2045275_+|acyl-CoA-synthetase
MAVRDIHDIEQIERVPLHARALPANTLQVFDERAAKTPDAPALTFFLDAGRLDRSHTWTFAELRADIVRTANVLASVGIGAGDVAAFVLPNLPDTHFAIWGGEAAGIAMAINPLLDGAQIAELVDAARAKVLICVAPTPGVDIWPKLAPHLDAMPTVETVIWVDLRPYVSLPKRAALAWIERREKARLRGARVRIVNLHAEMRRQPGDRLIRPRAIGPDEPSSYFCTGGTTGRPKIAVRTHGSEVFDVWAASETQARDDEGARTVFCGLPLFHVNGQLVTGLMAWLRGHHVVLGTPQGYRGKNVIARFWAIVEAYRINAFSGVPTLFAALLQQPVGRHDIGSLEYAACGAAPMPVELARSFERTTGVKIVEGYGLTESACIASLNPLDGERRIGSIGLRLPYQRMRAVIVDDTGRYVRDALVDEVGLIALAGPNVFRGYLDPAHERGLWIDIAGERWLNTGDLGRRDAHGYFWLVGRKKELIIRGGHNIDPRIIEDALAAHPAVALAAAIGRPDAHAGELPVAYVQLKAGASADEAALLAFAADAIAERAAVPKHVRILEAVPTTAVGKIFKPQLQRLEIADVVAACARDAQVALERVDVVQDARRGLVAQVAVRGAREALAERLARYAFPVDWSGDGAHARASEAQRDAAAARERAS
>NC_006350.1|WP_004521531.1|2042723_2042912_-|DUF3562-domain-containing-protein
MVQNRVDEIVQAIASETHTPAEAVSRLYEETLAEYSEGARVRDYLTVLVAKRVRETLRNRTH
>NC_006350.1|WP_004192820.1|2042399_2042687_+|hypothetical-protein
MRRSTDPDAFIDESKPRALTRCRDDATIYRCRMALQAKRSAHSFAVFDDDRMSCNAVSRIPRPPEPYGARTVAARPARMHRSPSPRSPRPAGSGD
>NC_006350.1|WP_004531281.1|2040268_2042011_-|methyl-accepting-chemotaxis-citrate-transducer
MNFQNMTVSTKLTLAFGALVGLVLLVSVLALHALGDANDRFASYVSGISARAEAAEQVRTAVDRRAIAARNLVLVTKPADVELEKAAVTQAEDDVQAHLRRLKELLSSASDGNDKARGLVADIDRVEAQYGPVALAIVNAALNNRHDEAITMMNDQCRPLLAQLVKATNAYSEYTRGRAQEMVRESADHYASQRLLLVGLCAAAIGAAVIAAILIARGLMRALGAEPATLGDVTRRVANGDLSPVAGAQTAPSGSVLASMGEMQASLVRLIGQVSTAADSIATGSSQIASGNQDLSSRTEHQASSLQETASSMEELTSTVRQNAENAQQASSLAANASEVAQKGSTVVGQVVDTMTDISQSSEKVAEITGIIESIAFQTNILALNAAVEAARAGEQGRGFAVVASEVRSLAQRSSSAAKEIKDLINASVQKIHGGSALAGEAGKTMTEVTQAVARVTDIMGEIAAASGEQSRGIEQVNQAIAQMDEVTQQNAALVEEAAAASKSLEEQGRHLTQAVSFFRASAASAAPQARHAAQAKPKAKRGVAAPAPAPRAAHAAPTFNKPAPALAAAATASDDWQTF
>NC_006350.1|WP_004198172.1|2053355_2053688_+|hypothetical-protein
MRICIENIQPGVTREELQAFLFKYTGKTFTDIQFIGQSGPRPGALIDIDGANWSALAEIRRRLHGMYWKRRRIGVWLFSFWDRSDAAEARRQREARTRQTRSTPMTTLRR
>NC_006350.1|WP_004192541.1|2053848_2055309_+|arginine-ornithine-antiporter
MAEVTQEQGVAAKSAANKLRLGALTALVVGSMIGGGIFSLPQNMAATAEAGAILIGWAITAIGMLTLAFVFQTLANRKPQLDGGVYAYAQAGFGDYMGFSSAWGYWISAWLGNVGYFVLLFSTLGYFFPVFGEGNTPAAIAGASVLLWAVHFLVLRGIREAAFVNLVTTVAKIVPLVVFILIGFFAFKLDVFRTDIWGRANPSLGSVMNQVRNMMLVTVWVFIGIEGASIFSARAEKRSDVGRATVIGFVGVLLALVLVNVLSLGIMTQPQLAKLQNPSMAAVLEHVVGHWGAVLISVGLVVSLAGALLSWVLLCAEIMFSAAKDRTMPAFLRKENANHVPANALWLTNAMVQVFLLITLFSQSTYLSLIYLATSMILIPYFWSAAYALLIAVRGETYEGDARARRKDLFVAALAVLYAVWLLYAGGLKYLLLSALLYAPGALFFAKAKRELGKPVFTAAEKLIFAAAAAAALAAAYALHSGLITL
>NC_006350.1|WP_004526983.1|2055326_2056583_+|arginine-deiminase
MSQAIPQVGVHSEVGKLRKVLVCSPGLAHQRLTPSNCDELLFDDVMWVNQAKRDHFDFVSKMRERGVEVLEMHNLLTETVQNPAALKWILDRKITPDNVGIGLVDEVRAWLEGLEPRALAEFLIGGVAASDIAGAERSKVLTLFRDYLGKSSFVLPPLPNMMFTRDTSCWIYGGVTLNPMHWPARRQETLLVAAVYKFHPAFTDAKFDVWYGDPDRDHGMATLEGGDVMPIGRGVVLVGMGERTSRQAVGQLAQALFAKGAAERVIVAGLPNSRASMHLDTVFSFCDRDLVTVFPEVVNRIVPFTLRPGGDARYGIDIEREDKPFVDVVAQALGLKSLRVVETGGNDFAAEREQWDDGNNMVCIEPGVVVGYDRNTYTNTLLRKAGVEVITIGSSELGRGRGGGHCMTCPVLRDPVDY
>NC_006350.1|WP_004521536.1|2056647_2057658_+|ornithine-carbamoyltransferase
MSFNLHNRNLLSLIHHNARELRYLLDLARDLKRAKYSGTEQPRLLRKNIALIFEKTSTRTRCAFEVAAYDQGANVTYIDPASSQIGHKESMRDTARVLGRMYDAIEYRGFSQEIVEELAHHAGVPVFNGLTDEYHPTQMLADVMTMREHSDKPLHDIRYAYLGDARNNMGNSLLLIGAKLGMDVRIGAPKSLWPAADFIAQCEAFAAESGARLTLTEDPYEAVKGVDFIHTDVWVSMGEPVEAWDERINALLPYQVNRKLIESTGNPRTRFMHCLPSFHNCETKVGKQIAERYPHLKDGIEVTDEVFESPRCIAFEQAENRMHTIKAVLVSTLGGI
>NC_006350.1|WP_004550484.1|2057746_2058685_+|carbamate-kinase
MRIVIALGGNALLQRNQPMTEVQQRENVKIAVAQIAQIAPGNELVIAHGNGPQVGLLALQGAAYPAVAPYPLDVLGAQTEGMIGYLIEQEMGNLLPPDAPFATLLTQVEVDPADPAFEHPTKPIGPVYSRDEAERLAQEKGWHIAPDGDKFRRVVPSPRPRRIFEIRPVKWLLEKGTIVICAGGGGIPTRYDANGKLSGVEAVIDKDLCASLLARELSADLLVIATDVDGAYLDWGKPTQALIEAAHPDELERLGFAAGSMGPKVQAAIEFARQTGHDAVIGSLADIVAIAEGRAGTRISVKVDGIRYRRPR
>NC_006350.1|WP_004521539.1|2058927_2059722_-|SDR-family-oxidoreductase
MTGKRILVTGAGSGFGREVALRLAAKGHCVIAGVQIAPQITELSAEAARRGLALDAVKLDVTCARERAQAARWDVDVLLNNAGAGEAGALVDLPVDIVRELFETNVFGPLELTQQVARGMIARGRGRIVFVSSIAGLITGAYTGAYCASKHALEAIAEAMHLELAAHGVQIAVVNPGPYRTGFNDRMMETPRRWLDPARDAATPETLTFPLEQFDPQEMIEKMVDVTEADGGLFRNLLPAAAEQIVRDEQAHAWTRRQNERRGA
>NC_006350.1|WP_004521540.1|2059718_2060168_-|heme-binding-protein
MSPELTLERALRIVEAGVAHAARLSAAGAAVAIAVVDAGAHLAAFARMDDAFIGAIDLATRKAGTAARFRMPSASLGALSGAGGPVRSIEHSNGGLVTFGGGLPLVDAHGRCVGAVGVSGGTVDDDAAIAQVCVDAFITLLNAAQGART
>NC_006350.1|WP_004192049.1|2060265_2061186_+|LysR-family-transcriptional-regulator
MTMKRDPLGGLHVFMSVVTHGNFTRAAAALGLTPAAVSLAIGQLESELKVKLFSRSTRGVSLTEAGQRYYDATAQPYRQVVDARDALNDARDEPEGLLRISALHLAKSVVTADVLAEFFRRYPKVSVEIRYEDHLVDIVKERLDAGIRLADRLQPGMVGVKIAPALTCALVATPGYLAQHGVPAKLADLARHMCIRFRFPKSGRLHKWPLRDGRRDVELDVAGRFVSTDTGAVIDAARAGAGIAFVFMRERIEDDLRRGTLREVLPGACRTLPPMWLYYANRKHVPPKLRAFIAVLREHAAADARR
>NC_006350.1|WP_004526980.1|2061470_2062175_+|glutathione-S-transferase-N-terminal-domain-containing-protein
MSDLSEFPITKKWPAQHPERIQLYSLPTPNGVKVSILLEETELPYEAHVVRFDTNDQMSPEFLSLNPNNKIPAIIDPHGPGGKPLALFESGAILLYLAEKTGRFIPADPARRYETIQWLMFQMGGIGPMFGQLGFFHKFAGREYEDKRPRERYVGEAKRLLGVLDGRLAHRRWIMDDAYTIADIATFPWVRNLIGFYEARELVEFDRYPNVARALDAFVARPAVARGLNIPARP
>NC_006350.1|WP_011205058.1|2062730_2063270_+|winged-helix-turn-helix-transcriptional-regulator
MKLIGKQSGAALPLDETLPAPDAAPLRLDEWLPYQLFLPAQHVARVLAEFYGPRYGIDQPAWRILATIVDRPGTNARQIGAALGMDAVSVSRGIAQLVGAGFARRDAARNDRRYACVMATPAGRAAFDDIAAVCIAVERRLLDVLTPEERATLAVALPKIGRESERIAIVGWQRLLDGA

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Crispr_ID: NC_006350_3

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_006350_3

3969167-3969238

Orphan

Consensus_repeat	Method
CGTCGTCGAACCCAATCGACCTCA	CRISPRCasFinder

1 spacers

The CRISPR arrays of NC_006350_3

>merge|NC_006350|3|3969167-3969238|CRISPRCasFinder
CGTCGTCGAACCCAATCGACCTCACTCCCGCAAAGCGGCAGCCGCACCACGCGTCGAACCCAATCGACCTCA

>NC_006350|3|3|3969167-3969238|CRISPRCasFinder
CGTCGTCGAACCCAATCGACCTCA	CTCCCGCAAAGCGGCAGCCGCACC
ACGCGTCGAACCCAATCGACCTCA

Protein	Signature genes	Signature genes Name	Protein_function
NC_006350.1\|WP_009910242.1\|3966422_3966755_-\|type-II-toxin-antitoxin-system-RelE/ParE-family-toxin	unknown	unknown	gnl\|CDD\|377579
NC_006350.1\|WP_011205299.1\|3967731_3968511_-\|bacteriophage-like-protein	unknown	unknown	unknown
NC_006350.1\|WP_004195754.1\|3962263_3962908_-\|lytic-polysaccharide-monooxygenase	unknown	unknown	gnl\|CDD\|237309
NC_006350.1\|WP_004542760.1\|3974690_3974993_-\|hypothetical-protein	unknown	unknown	unknown
NC_006350.1\|WP_011205301.1\|3969660_3971037_-\|bacteriophage-related-lipoprotein	unknown	unknown	gnl\|CDD\|224367
NC_006350.1\|WP_004195757.1\|3963948_3964173_+\|hypothetical-protein	unknown	unknown	unknown
NC_006350.1\|WP_009938965.1\|3974400_3974607_-\|bacteriophage-coat-protein	unknown	unknown	unknown
NC_006350.1\|WP_004524472.1\|3977436_3979524_-\|UvrD-helicase-domain-containing-protein	unknown	unknown	gnl\|CDD\|130146
NC_006350.1\|WP_009938954.1\|3964454_3966017_-\|ATP-binding-protein	unknown	unknown	gnl\|CDD\|379114
NC_006350.1\|WP_004552489.1\|3976224_3977124_+\|cytochrome	unknown	unknown	gnl\|CDD\|225784
NC_006350.1\|WP_004266306.1\|3963414_3963732_-\|hypothetical-protein	unknown	unknown	unknown
NC_006350.1\|WP_009938963.1\|3972213_3973947_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|283306
NC_006350.1\|WP_009938955.1\|3966097_3966415_-\|transcriptional-regulator	unknown	unknown	gnl\|CDD\|238045
NC_006350.1\|WP_045606441.1\|3979821_3980622_+\|hypothetical-protein	unknown	unknown	unknown
NC_006350.1\|WP_004525720.1\|3960413_3962075_-\|FAD-binding-oxidoreductase	unknown	unknown	gnl\|CDD\|223354
NC_006350.1\|WP_162486671.1\|3966796_3967540_-\|tyrosine-type-recombinase/integrase	unknown	unknown	gnl\|CDD\|271177
NC_006350.1\|WP_009938961.1\|3971033_3971939_-\|AAA-family-ATPase	unknown	unknown	gnl\|CDD\|283385
NC_006350.1\|WP_004198237.1\|3960131_3960266_+\|hypothetical-protein	unknown	unknown	unknown
NC_006350.1\|WP_020850070.1\|3974010_3974334_-\|hypothetical-protein	unknown	unknown	unknown
NC_006350.1\|WP_009938962.1\|3971935_3972217_-\|DUF2523-domain-containing-protein	unknown	unknown	gnl\|CDD\|371214

Protein	Function_ID	Function_description	E-value
NC_006350.1\|WP_009910242.1\|3966422_3966755_-\|type-II-toxin-antitoxin-system-RelE/ParE-family-toxin	gnl\|CDD\|377579	pfam05973, Gp49, Phage derived protein Gp49-like (DUF891). This family consists of hypothetical bacterial proteins of unknown function as well as phage Gp49 proteins.	6.4606e-34
NC_006350.1\|WP_004524472.1\|3977436_3979524_-\|UvrD-helicase-domain-containing-protein	gnl\|CDD\|130146	TIGR01074, ATP-dependent_DNA_helicase_Rep, ATP-dependent DNA helicase Rep. Designed to identify rep members of the uvrD/rep subfamily. [DNA metabolism, DNA replication, recombination, and repair].	0
NC_006350.1\|WP_009938963.1\|3972213_3973947_-\|hypothetical-protein	gnl\|CDD\|283306	pfam05616, Neisseria_TspB, Neisseria meningitidis TspB protein. This family consists of several Neisseria meningitidis TspB virulence factor proteins.	1.69968e-18
NC_006350.1\|WP_011205301.1\|3969660_3971037_-\|bacteriophage-related-lipoprotein	gnl\|CDD\|224367	COG1450, PulD, Type II secretory pathway, component PulD [Cell motility and secretion / Intracellular trafficking and secretion].	6.24826e-35
NC_006350.1\|WP_009938954.1\|3964454_3966017_-\|ATP-binding-protein	gnl\|CDD\|379114	pfam13304, AAA_21, AAA domain, putative AbiEii toxin, Type IV TA system. Several members are annotated as being of the abortive phage resistance system, in which case the family would be acting as the toxin for a type IV toxin-antitoxin resistance system.	7.70499e-13
NC_006350.1\|WP_004552489.1\|3976224_3977124_+\|cytochrome	gnl\|CDD\|225784	COG3245, CycB, Cytochrome c5 [Energy production and conversion].	1.07868e-20
NC_006350.1\|WP_009938955.1\|3966097_3966415_-\|transcriptional-regulator	gnl\|CDD\|238045	cd00093, HTH_XRE, Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators.	3.76716e-10
NC_006350.1\|WP_004525720.1\|3960413_3962075_-\|FAD-binding-oxidoreductase	gnl\|CDD\|223354	COG0277, GlcD, FAD/FMN-containing dehydrogenases [Energy production and conversion].	2.2097e-19
NC_006350.1\|WP_162486671.1\|3966796_3967540_-\|tyrosine-type-recombinase/integrase	gnl\|CDD\|271177	cd00796, INT_Rci_Hp1_C, Shufflon-specific DNA recombinase Rci and Bacteriophage Hp1_like integrase, C-terminal catalytic domain. Rci protein is a tyrosine recombinase specifically involved in Shufflon type of DNA rearrangement in bacteria. The shufflon of plasmid R64 consists of four invertible DNA segments which are separated and flanked by seven 19-bp repeat sequences. RCI recombinase facilitates the site-specific recombination between any inverted repeats results in an inversion of the DNA segment(s) either independently or in groups. HP1 integrase promotes site-specific recombination of the HP1 genome into that of Haemophilus influenza. Bacteriophage Hp1_like integrases are tyrosine based site specific recombinases. They belong to the superfamily of DNA breaking-rejoining enzymes, which share the same fold in their catalytic domain and the overall reaction mechanism. The catalytic domain contains six conserved active site residues. Their overall reaction mechanism is essentially identical and involves cleavage of a single strand of a DNA duplex by nucleophilic attack of a conserved tyrosine to give a 3' phosphotyrosyl protein-DNA adduct. In the second rejoining step, a terminal 5' hydroxyl attacks the covalent adduct to release the enzyme and generate duplex DNA.	1.73398e-55
NC_006350.1\|WP_009938961.1\|3971033_3971939_-\|AAA-family-ATPase	gnl\|CDD\|283385	pfam05707, Zot, Zonular occludens toxin (Zot). This family consists of bacterial and viral proteins which are very similar to the Zonular occludens toxin (Zot). Zot is elaborated by bacteriophages present in toxigenic strains of Vibrio cholerae. Zot is a single polypeptide chain of 44.8 kDa, with the ability to reversibly alter intestinal epithelial tight junctions, allowing the passage of macromolecules through mucosal barriers.	3.18985e-25
NC_006350.1\|WP_004195754.1\|3962263_3962908_-\|lytic-polysaccharide-monooxygenase	gnl\|CDD\|237309	PRK13211, PRK13211, N-acetylglucosamine-binding protein GbpA.	8.19814e-39
NC_006350.1\|WP_009938962.1\|3971935_3972217_-\|DUF2523-domain-containing-protein	gnl\|CDD\|371214	pfam10734, DUF2523, Protein of unknown function (DUF2523). This is a family of phage related proteins whose function is uncharacterized.	4.77177e-10

>NC_006350.1|WP_011205299.1|3967731_3968511_-|bacteriophage-like-protein
MHDASIGDFSPFRREWVIRGRNFGDGQVEVTATRFDRYMGALSLNARPKAKRGESENSESNLLDAAKRAKQQVRLRCKAIGADRMITLTYRENMQDKARLKRDFDALRRRLAKLSTFQYVATPERQKRGAWHLHVAVRGRQNYRVLRSIWQSIVGVGNGQINVRNPFKERGLRHKLAAYLAKYITKDFAEHALNEKRYWTSRGVVVPEVMPIDHIAANDPAEALKIAFKAALQAGATLDRCQAFWRQELGVFWLSTREN
>NC_006350.1|WP_162486671.1|3966796_3967540_-|tyrosine-type-recombinase/integrase
MSALKRVDVRKYVAVRLADGVQESTVKRELKFLSAAINFVRLECDCSDLPNPAQSLGLNGGEHRVRWISRAEASALILSASAYAKRPHLANFVRLALSTGCRKNELLALDWCRVDFEHSFLRLNAEHTKNGKRRVVPLNSAALSALRDQRDWVERKCSGSEWVFPAWSGKRIQTLQKGFNAACARVGIENFRIHDLRHTFASWLVMEGVSLYVVKDLLGHSSITVTERYAHLSPDQGRAAVQKLLPL
>NC_006350.1|WP_009910242.1|3966422_3966755_-|type-II-toxin-antitoxin-system-RelE/ParE-family-toxin
MKFDWTVVYYNERVKRDVFAFPAGILADYLRLLDLMQEFGADLRMPHSRAMGNGLFELRPKGREGIGRVFYCTHVGRQVVVLHSFVKKTQETPQHELRIAQARLREVRNG
>NC_006350.1|WP_009938955.1|3966097_3966415_-|transcriptional-regulator
MKRVRAEGFNPIPHTADDTARLLADSKVKAAYDALEDEYSALRAILAARQEAGLTQAQVAERMGTTASAVSRLEASLTSEKHSPSFATLRKYAAACGKRLVISFA
>NC_006350.1|WP_009938954.1|3964454_3966017_-|ATP-binding-protein
MTMKYRESQVDKELRQWFAKDMSKALLRRIMLIRGSLRGINSLDISFTYPITAFAGINGAGKSTILALACCAYHANKNGFKLPRRKNPYYTFSDFFIRHKEEAEPDGIEISYAIAYNNWKKTDSFPNGEGVAYQRRKKNKGGKWNDYQARVRKTVVFLGIERIVPHSERSQSRSYSRAFADTVPKGWEDKVREAVGFILSKKYDDLRYLEYSRYRLPIVKIGDLVYSGFNMGAGENALFEIFSTIYSCGEQALLVLDEIELGLHVKAQKLFMKKLKEVCNETGTQVICTTHSREIFECLPDDARYFVETIGGKTRLIGGISPEFAFAKMGAPGGNELDIFVEDDVARSILQAILPASIRTRVTIKVIGSATAIARQLAAHYVRKDQKPTLAIFDGDQRAKDADNLGHAKKMAENAGAEFDAWYKEHVGYLPGETWPEAWLVQKAIEAKMSTAVALAVEPDAVTGVLEYALQAGKHNEFYEIAKNVGLDKQQCLERLSAAVCASFPGDFAALLKLVADQLR
>NC_006350.1|WP_004195757.1|3963948_3964173_+|hypothetical-protein
MTHPESAGEPGDLNRILDSRIISRRLGDWRAYIRHAYVRVSAVRSGWEVRREPGGGEMMGMVKGYVYLSADYLA
>NC_006350.1|WP_004266306.1|3963414_3963732_-|hypothetical-protein
MHPIVRRLLLVAVFSPLSAAAFNEEQGYNQCILNALRGSRNPTATGLMRNACDQLYRNWAMLQPRDRAYHTCILDSLGDVKDTYAVQQLAAACSRQSEGAGPTFK
>NC_006350.1|WP_004195754.1|3962263_3962908_-|lytic-polysaccharide-monooxygenase
MSTTDSRSATKSSSISPRHGRVITPESRAVYLYEAGRLDFGQVNELEGGKFFPATQSGLRDPDAPDDVANGMPPRDGEIASGGRTADARAQLNEPDSVAHWQKHAVRSGQSLQISWSYSMPHKTRRWTYWITKPGWDTQARLARAHFEPDPLKVYLNTYQPYWGPDADKELIPQGETIHEFNLPTRTGYHVLLAVWDVADTANAFYQVIDLNFA
>NC_006350.1|WP_004525720.1|3960413_3962075_-|FAD-binding-oxidoreductase
MSYVYVDGADPRHSTLQKGFNLRWPPTAEAGAAAIYVCRTADDVIAASRDALAKGCRITVRSGGHCYEGFVANRLPDDHGRPLAIIDLGLMSGFDIDDRGQIASPFDAAGAPRYRVRVAAGRQNWDGYVGLYKTMGKTLPGGSCYSVGAGGHIVGGGYGLLSRLHGLTVDWLTGVDILAPAAGGALGAKHVHSGSTDPADRALFIACRGGGGGNFGVILNYYFNALPNAPRTAYWLTLAYDWSHFTQASFGHFLQTYWDWFSRNDANWNAADPALANGGLFTLLKLQHRSAGPIVLAIQYTGKDGTVGGPEDAPFIDFVDTMNAAANRLPVVWDRFVAPNLPALGHPLAGLRIAHAARSALKMDWLYLTQTINTSGANRRGKYKSAYQIGNFGETEVDALWRYLNGADDPRLSQTLVQIDSYGGCVNANDESANPTSVYQRRSLLKSQYQTYWTNPADDAFHVEWLHDLFSAVHADQGGKPYRDASGRYEGCYINYPDIDMKYLGSDPAQIDPRWLDLYYGDKAASLIATKRSVDPSNLFMHEMSIPLTPPLG
>NC_006350.1|WP_004198237.1|3960131_3960266_+|hypothetical-protein
MKGDMDVERTYWFTAAQTRDLTRGTLYVWCFRSRVYAMCAGAFV
>NC_006350.1|WP_011205301.1|3969660_3971037_-|bacteriophage-related-lipoprotein
MRRYCGLIVALMLSSGCRIAAGAVPPLPTLPVDATIGTSPAIQIPAAPVSTPLKHVPGTAFDLRFVTVAQVVDLIYQDAMHTPYVLGPDVLADNRLVSFRLDDAVRDVRAVMVDFLDSLGFRVTTKNGVDYVARKAADSRARVDQEVFVYRPRYRSAESLRSLVEPVIGTRSMIPMSAIAATPSAVTSPVQVPGAPISTASDVAVAPAAAGVQARGNELVIVGSRDEVAMLRKLVPDLDTAPGEVVVRGWVYEVANTDSANSAWSIAVRLLSGQLRLSSGDTSSDASAMRFTGPGVDAAISALNADSRFKVVSSPHVRIVSGERVRLNVGQQVPTQSSVSYQGSSGTPVQSITYQDAGLIFDVEPTVMRDVIELKVREEISDFVATKTGVDTSPTKNTRQLQTVTRLKDGELVVLGGLIQDRDATARSGYSWLPSFFDGRSSSKQRTEVLLVLQVQRI
>NC_006350.1|WP_009938961.1|3971033_3971939_-|AAA-family-ATPase
MITLITGVPGSGKTLHAVWLLTKIAKGRRVLVDGIRDLAIEHVEIDEPWLRQWHEKAEAQDLIVIDEAQRIYPPTTVSQKPTPDVEQLHVHRHKGVDFILITQHPQRISKTVRDLVGRHIHVRNLFGLKRAMLYEWDHCHNPSSLKDAVKRQWPYPREVFKLYTSAEVHTKKQAVVPKALFLLPIGIVVFVVLAVKIYHKARDGFGAEPVRHVESAAAASNAVVARPIDTVKSSEWRVAGRYSVDGVGYVALVAMDGRLRAVPVRGFSGQGARLTGEVDGKTVAGWTGVQTVKTEQYGGAK
>NC_006350.1|WP_009938962.1|3971935_3972217_-|DUF2523-domain-containing-protein
MSWASLLVSLVGPIVTRVLVALGIGFVTVAGIDAALNQVIQWMTASAGGIPTDIANVLALGGVGDAIAYVLGGISARVSFYMLTSTTRMVFSK
>NC_006350.1|WP_009938963.1|3972213_3973947_-|hypothetical-protein
MSCREVNVRRRIIGVWIALFAVFAMMCNQQAHAQALLAPVENFVINRAEAAILTRIAIQRGFAANDPRIAATLAGMGKASTALNVVSTGAGVALAFAGAPVWATLLAGAGIIALGTALQIGLAKLQWNDTSVSIDVDAVPASAGDHYEAVSPPAAGVDPAYRKLLAPELWAAQAGIPTYRNGYCQPNDSVCNAYPTTPGTGSNVANFWLTRGNFDILPGTLDQAAQFMWYLHYYNGHCGLTSGCASDDRNVSSVRLFFAPTINIPGNPIEMYYTETGSQAYVGLDGKTRYKSYVTTAKARAFQYRSDIVPSLVAEDVSKLWPKLPPNVASIPLPSSTLTKLVDETWKRAATDPDYKGLPYEPVYDGLVKPWVDENPKQVPTLGDLFTAPAHPGKQVVIDPNVQPDPNANPNPNPGTNPGTNPGTNPGTNPGTNPGTNPGTNPSTNPGTDPSTNPGTNPGTNPGTNPGTNPDPKPDPKPDPKPDPKFCALYPDASACAPLGSANDVDVRRESKSVSLAPISIGLTNGVCPHPYEVEVFGAPLRFDYAPICELAAKLRPLVLLLGALLAGLIFVTGLTV
>NC_006350.1|WP_020850070.1|3974010_3974334_-|hypothetical-protein
MKRLLCVALVGVVFGVRAAPGIDVVTCGPAPASLAAGAQVPCTLPDGSAGVQQVVHLTLVNDGATGDAPISGGIEAGMAVGSAVFLVLAIAFGMRALRRFVDSASES
>NC_006350.1|WP_009938965.1|3974400_3974607_-|bacteriophage-coat-protein
MKKLFVAALSLASAGAFAADAGTPTMDVTSVVASINGVGPNIVLVGGAVLAVAAVTFGYRTVRSFIGR
>NC_006350.1|WP_004542760.1|3974690_3974993_-|hypothetical-protein
MSKQKLTILQVVPRGGISKRTNQPWEIHTAQCVLEQETSEGKQILVGTINLPNALKDSAPGDYLAEFALQQSMEGKLEPRIVSLVPFGRPTAKPAANANA
>NC_006350.1|WP_004552489.1|3976224_3977124_+|cytochrome
MSEAPHGAPIKTPGQLIAVVIASFVIPIAIIVLFATYANHAFRTGAGTDGLSDEAVAKRIAPLAQVDIKDANAPHVYKTGEEVYKAVCVTCHGTGAAGAPKFGDAAAWAPRIAAGYDEVLHLALTGKGAMPPRGGTNPDDYSDYEIARAVVYMANQGGAKFAEPAQPAANAAPASGAAAASAPGASDAAANSQAAAAMAAIAALPKAGEAPAAGANAESSASAGKALYESTCQACHATGVLNAPKFGNKADWAPRLKDSMDTVYNFALHGKGAMPPKGGSNASDADVKAAVDYMVNAAK
>NC_006350.1|WP_004524472.1|3977436_3979524_-|UvrD-helicase-domain-containing-protein
MSAGLNSAQSEAVRYLDGPCLVLAGAGSGKTRVITQKIAHLIEAKGFEPRHIAAVTFTNKAAAEMRERVGKLLEGKTLTTPGKEGRKVPVNQLTVCTFHSLGVQILRQEAEHVGLKPQFSIMDSDDCFGMIQEQIGTTDKGLIRKIQTIISLWKNGLVAPEEAMTIAANEDEHQAALVYRNYVATLHAYQAVDFDDLIRLPTELFARNEPVRDRWQNRLRYLLIDEYQDTNACQYELLKLLAGPRAAFTAVGDDDQAIYGWRGATLENLAQLGKDFPKLHVIKLEQNYRSTVRILTAANNVIANNPKLFEKKLWSEHGMGDSITVTPCNDEEHEAESVVFRLSAHKFERRTQFRDYAILYRGNFQARVFEQVLRRERIPYVLSGGQSFFDKAEIKDLCAYLRLIANADDDPAFIRAVTTPRRGIGNTTLEALGAFAGQAKVSLFEAVYMGGIEARLSARQVEPLRIFCDFIQRLTDRADKEPATVVLDDMMEAIHYEAYLYDAYDERQAQTKWQNVLEFLEWLKRKGTKPEAEQAVDGEAEGFHNADGLADTGKNLLGLIQTVALMSMLEGKEEDPDAVRLSTVHASKGLEYPHVFLVGVEEGIMPHSGGSDDGPIDDERIEEERRLMYVAITRAQRSLHLNWCKKRKRARETIVCEQSRFIAEMGLDEAPPPTPEEAPMTPKDRLASLKALLQK
>NC_006350.1|WP_045606441.1|3979821_3980622_+|hypothetical-protein
MLALKLTLVPLFLLLVSIAGRRWGPSIAGWLAGLPVVAGPILFLVAVERGPAFGAHAALLSLSAIAASEAFSFAYAWTCRRHRWPLALALAAGLAAWAAAASALARLPATPPAATAVAFAATCFGQSCLPRGATLAPRAPLSHADLAGRLAAGAALALAVTSLAGALGPAWSGLLAVFPLLGSVLAVSSHRAHGPDFVVPLLRGMVFGRFSFAAFCLCVALTLPRQPALQAFAEAAALSVAVQGATKRLAARGPRPTALAQTATPD

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NC_006350_3	3.1\|3969191\|24\|NC_006350\|CRISPRCasFinder	3969191-3969214	24	MN035431	Leviviridae sp. isolate H2_Bulk_35_scaffold_4486 hypothetical protein (H2Bulk354486_000001) gene, partial cds; hypothetical protein (H2Bulk354486_000002) gene, complete cds; and RNA-dependent RNA polymerase (H2Bulk354486_000003) gene, partial cds	917-940	2	0.917
NC_006350_3	3.1\|3969191\|24\|NC_006350\|CRISPRCasFinder	3969191-3969214	24	MK524491	Mycobacterium phage Whabigail7, complete genome	48031-48054	3	0.875
NC_006350_3	3.1\|3969191\|24\|NC_006350\|CRISPRCasFinder	3969191-3969214	24	MT498041	Mycobacterium phage KingCyrus, complete genome	49006-49029	3	0.875
NC_006350_3	3.1\|3969191\|24\|NC_006350\|CRISPRCasFinder	3969191-3969214	24	KX619650	Mycobacterium phage Jerm, complete genome	48140-48163	3	0.875
NC_006350_3	3.1\|3969191\|24\|NC_006350\|CRISPRCasFinder	3969191-3969214	24	JN408460	Mycobacterium phage Turbido, complete genome	48033-48056	3	0.875
NC_006350_3	3.1\|3969191\|24\|NC_006350\|CRISPRCasFinder	3969191-3969214	24	MH077576	Mycobacterium phage AbbyPaige, complete genome	48089-48112	3	0.875
NC_006350_3	3.1\|3969191\|24\|NC_006350\|CRISPRCasFinder	3969191-3969214	24	KU985095	Mycobacterium phage ChipMunk, complete genome	48992-49015	3	0.875
NC_006350_3	3.1\|3969191\|24\|NC_006350\|CRISPRCasFinder	3969191-3969214	24	MH825704	Mycobacterium phage LilTurb, complete genome	48017-48040	3	0.875
NC_006350_3	3.1\|3969191\|24\|NC_006350\|CRISPRCasFinder	3969191-3969214	24	KU985093	Mycobacterium phage EvilGenius, complete genome	48993-49016	3	0.875

1. spacer 3.1|3969191|24|NC_006350|CRISPRCasFinder matches to MN035431 (Leviviridae sp. isolate H2_Bulk_35_scaffold_4486 hypothetical protein (H2Bulk354486_000001) gene, partial cds; hypothetical protein (H2Bulk354486_000002) gene, complete cds; and RNA-dependent RNA polymerase (H2Bulk354486_000003) gene, partial cds) position: , mismatch: 2, identity: 0.917

ctcccgcaaagcggcagccgcacc	CRISPR spacer
ctcctgcaaagcggcagcctcacc	Protospacer
****.************** ****

2. spacer 3.1|3969191|24|NC_006350|CRISPRCasFinder matches to MK524491 (Mycobacterium phage Whabigail7, complete genome) position: , mismatch: 3, identity: 0.875

ctcccgcaaagcggcagccgcacc	CRISPR spacer
ctcccgcagagcgacagccgcacg	Protospacer
********.****.*********

3. spacer 3.1|3969191|24|NC_006350|CRISPRCasFinder matches to MT498041 (Mycobacterium phage KingCyrus, complete genome) position: , mismatch: 3, identity: 0.875

ctcccgcaaagcggcagccgcacc	CRISPR spacer
ctcccgcagagcgacagccgcacg	Protospacer
********.****.*********

4. spacer 3.1|3969191|24|NC_006350|CRISPRCasFinder matches to KX619650 (Mycobacterium phage Jerm, complete genome) position: , mismatch: 3, identity: 0.875

ctcccgcaaagcggcagccgcacc	CRISPR spacer
ctcccgcagagcgacagccgcacg	Protospacer
********.****.*********

5. spacer 3.1|3969191|24|NC_006350|CRISPRCasFinder matches to JN408460 (Mycobacterium phage Turbido, complete genome) position: , mismatch: 3, identity: 0.875

ctcccgcaaagcggcagccgcacc	CRISPR spacer
ctcccgcagagcgacagccgcacg	Protospacer
********.****.*********

6. spacer 3.1|3969191|24|NC_006350|CRISPRCasFinder matches to MH077576 (Mycobacterium phage AbbyPaige, complete genome) position: , mismatch: 3, identity: 0.875

ctcccgcaaagcggcagccgcacc	CRISPR spacer
ctcccgcagagcgacagccgcacg	Protospacer
********.****.*********

7. spacer 3.1|3969191|24|NC_006350|CRISPRCasFinder matches to KU985095 (Mycobacterium phage ChipMunk, complete genome) position: , mismatch: 3, identity: 0.875

ctcccgcaaagcggcagccgcacc	CRISPR spacer
ctcccgcagagcgacagccgcacg	Protospacer
********.****.*********

8. spacer 3.1|3969191|24|NC_006350|CRISPRCasFinder matches to MH825704 (Mycobacterium phage LilTurb, complete genome) position: , mismatch: 3, identity: 0.875

ctcccgcaaagcggcagccgcacc	CRISPR spacer
ctcccgcagagcgacagccgcacg	Protospacer
********.****.*********

9. spacer 3.1|3969191|24|NC_006350|CRISPRCasFinder matches to KU985093 (Mycobacterium phage EvilGenius, complete genome) position: , mismatch: 3, identity: 0.875

ctcccgcaaagcggcagccgcacc	CRISPR spacer
ctcccgcagagcgacagccgcacg	Protospacer
********.****.*********

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

102608 : 212819

116

Burkholderia_phage(46.67%)

capsid,plate,holin,tRNA,terminase,tail,portal,head,protease,transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_038802333.1\|102608_103729_-\|transposase	IS3 family transposase	S5WIU1	Leptospira_phage	3.6e-49	39.5
WP_038719189.1\|104027_104717_-	hypothetical protein	NA	NA	NA	NA
WP_004525828.1\|105282_106440_+	DUF4382 domain-containing protein	NA	NA	NA	NA
WP_004533510.1\|106502_106658_+	lipoprotein	NA	NA	NA	NA
WP_004524602.1\|107001_107172_-	hypothetical protein	NA	NA	NA	NA
WP_004524603.1\|107333_107894_+	spermidine N1-acetyltransferase	NA	NA	NA	NA
WP_004525830.1\|108379_108727_+	hypothetical protein	NA	NA	NA	NA
WP_004197759.1\|108942_109497_+	YaeQ family protein	NA	NA	NA	NA
WP_004197761.1\|109681_110098_-	VOC family protein	NA	NA	NA	NA
WP_004553740.1\|110499_111594_+	bifunctional DNA-binding transcriptional regulator/O6-methylguanine-DNA methyltransferase Ada	A0A0G2Y1B6	Acanthamoeba_polyphaga_mimivirus	5.0e-19	36.9
WP_004553741.1\|111590_112532_+	DNA-3-methyladenine glycosylase 2 family protein	NA	NA	NA	NA
WP_004545670.1\|112690_114304_+	glutamate--cysteine ligase	NA	NA	NA	NA
WP_011204744.1\|114322_115771_-	RNA polymerase sigma factor RpoD/SigA	A0A2I7SAT0	Vibrio_phage	2.2e-30	33.5
WP_004545687.1\|116033_116582_-	hypothetical protein	NA	NA	NA	NA
WP_009935882.1\|117178_117748_-	Spy/CpxP family protein refolding chaperone	NA	NA	NA	NA
WP_004543087.1\|117850_118819_-	LysR family transcriptional regulator	NA	NA	NA	NA
WP_009935883.1\|118961_120056_+	polyamine ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_009935884.1\|120084_121197_+	histone deacetylase	A0A2K9KZC4	Tupanvirus	3.5e-36	30.5
WP_004535322.1\|121207_122083_+	N-carbamoylputrescine amidase	A7IVZ1	Paramecium_bursaria_Chlorella_virus	2.1e-73	47.0
WP_161605795.1\|122437_122749_+	hypothetical protein	NA	NA	NA	NA
WP_045606483.1\|123333_124425_+\|portal	phage portal protein	A4JWQ2	Burkholderia_virus	8.0e-195	99.7
WP_004523107.1\|124498_124783_-	hypothetical protein	NA	NA	NA	NA
WP_004200731.1\|124779_125262_-	DUF2778 domain-containing protein	NA	NA	NA	NA
WP_011204746.1\|125799_126804_-	SIR2 family protein	NA	NA	NA	NA
WP_154585512.1\|126906_127275_-	hypothetical protein	NA	NA	NA	NA
WP_004200732.1\|127677_128082_+	PaaI family thioesterase	NA	NA	NA	NA
WP_004189208.1\|128119_128989_+	patatin-like phospholipase family protein	NA	NA	NA	NA
WP_004525849.1\|129109_130126_-	D-2-hydroxyacid dehydrogenase family protein	NA	NA	NA	NA
WP_004189230.1\|130564_131620_+	LysR family transcriptional regulator	NA	NA	NA	NA
WP_004525850.1\|131842_134452_-	DNA topoisomerase III	A0A2P1ELA0	Moumouvirus	7.7e-18	25.7
WP_004190199.1\|134662_135034_-	thioredoxin family protein	NA	NA	NA	NA
WP_009935893.1\|135093_136284_-	DNA-protecting protein DprA	S6BFL3	Thermus_phage	2.0e-21	39.2
WP_004525852.1\|136512_137016_+	peptide deformylase	A0A067XQZ3	Caulobacter_phage	2.1e-12	34.3
WP_004549892.1\|137047_138031_+\|tRNA	methionyl-tRNA formyltransferase	E3SNR5	Prochlorococcus_phage	1.3e-07	38.0
WP_004189288.1\|138151_138787_+	LysE family translocator	NA	NA	NA	NA
WP_004189409.1\|138896_139754_+\|protease	zinc metalloprotease HtpX	NA	NA	NA	NA
WP_004189046.1\|140227_141637_+	16S rRNA (cytosine(967)-C(5))-methyltransferase RsmB	NA	NA	NA	NA
WP_004188929.1\|141633_142224_+	DUF4390 domain-containing protein	NA	NA	NA	NA
WP_004523096.1\|142225_144634_+	PAS domain-containing sensor histidine kinase	NA	NA	NA	NA
WP_009935896.1\|144634_145318_+	response regulator	NA	NA	NA	NA
WP_011204748.1\|147387_150180_-	toprim domain-containing protein	K4NXL6	Burkholderia_phage	0.0e+00	99.5
WP_004524471.1\|150191_150446_-	hypothetical protein	K4NZY7	Burkholderia_phage	4.5e-40	100.0
WP_038783529.1\|150442_150802_-	hypothetical protein	K4NXB4	Burkholderia_phage	2.5e-60	99.2
WP_004524469.1\|150804_151011_-	hypothetical protein	K4NZT3	Burkholderia_phage	2.7e-35	100.0
WP_004531069.1\|151179_151419_-	hypothetical protein	K4PAZ5	Burkholderia_phage	1.4e-35	100.0
WP_004524467.1\|151422_151617_-	hypothetical protein	K4NXL1	Burkholderia_phage	1.6e-26	100.0
WP_004524466.1\|151660_151858_-	hypothetical protein	K4NZY3	Burkholderia_phage	1.6e-29	100.0
WP_004549898.1\|151863_152082_-	hypothetical protein	K4NXB1	Burkholderia_phage	1.1e-34	100.0
WP_004524465.1\|152097_152643_-	Bro-N domain-containing protein	K4NZS9	Burkholderia_phage	7.8e-98	100.0
WP_004549899.1\|152728_152977_-	ogr/Delta-like zinc finger family protein	K4PAZ0	Burkholderia_phage	3.0e-41	100.0
WP_004549900.1\|152964_153261_-	phage DNA-binding protein	E5E3P2	Burkholderia_phage	5.4e-37	84.3
WP_004524462.1\|153264_153501_-	hypothetical protein	K4NZX7	Burkholderia_phage	6.9e-35	98.7
WP_004524461.1\|153584_154043_+	helix-turn-helix transcriptional regulator	E5E3P4	Burkholderia_phage	2.1e-59	80.1
WP_004524460.1\|154095_154845_+	phage-encoded membrane protein	E5E3P5	Burkholderia_phage	4.7e-53	43.1
WP_004524459.1\|154887_155388_+	hypothetical protein	NA	NA	NA	NA
WP_011204752.1\|155395_156493_-	phage late control D family protein	K4PAY4	Burkholderia_phage	2.7e-198	98.3
WP_011204753.1\|156492_156918_-\|tail	phage tail protein	A4JWS2	Burkholderia_virus	9.7e-72	99.3
WP_045606417.1\|156935_159896_-	hypothetical protein	A4JWX4	Burkholderia_virus	0.0e+00	96.2
WP_011204755.1\|159898_160012_-\|tail	GpE family phage tail protein	A4JWX5	Burkholderia_virus	1.9e-14	100.0
WP_004531064.1\|160020_160365_-\|tail	phage tail assembly protein	K4NXA3	Burkholderia_phage	1.0e-55	100.0
WP_004524455.1\|160422_160932_-\|tail	phage major tail tube protein	K4NZR9	Burkholderia_phage	4.9e-94	100.0
WP_004531063.1\|160947_162120_-\|tail	phage tail sheath protein	Q45YG5	Burkholderia_virus	6.8e-224	100.0
WP_011204756.1\|162175_162847_-\|tail	phage tail fiber assembly protein	K4NXJ9	Burkholderia_phage	6.6e-115	99.6
WP_045606415.1\|162863_165227_-	phage Tail collar domain protein	A4JWS9	Burkholderia_virus	0.0e+00	98.9
WP_009941339.1\|165237_165792_-\|tail	phage tail protein I	K4NXA0	Burkholderia_phage	8.5e-100	99.5
WP_011204758.1\|165784_166690_-\|plate	baseplate assembly protein	A4JWT1	Burkholderia_virus	6.1e-164	99.7
WP_004556607.1\|166686_167049_-\|plate	phage baseplate assembly protein	K4PAX6	Burkholderia_phage	5.0e-61	99.2
WP_009941342.1\|167045_167726_-\|plate	phage baseplate assembly protein V	A4JWT3	Burkholderia_virus	1.9e-122	99.1
WP_011204759.1\|167899_168658_+	site-specific DNA-methyltransferase	K4NZW3	Burkholderia_phage	1.1e-137	95.5
WP_011204760.1\|169057_169525_-	phage virion morphogenesis protein	K4NZQ8	Burkholderia_phage	3.9e-74	94.2
WP_011204761.1\|169521_169938_-\|tail	phage tail protein	A4JWT7	Burkholderia_virus	1.8e-70	97.1
WP_009909361.1\|170042_170483_-	phage-encoded lipoprotein	K4NXJ2	Burkholderia_phage	4.7e-69	98.6
WP_011204763.1\|170479_171292_-	DUF3380 domain-containing protein	A4JWZ0	Burkholderia_virus	1.2e-147	98.1
WP_004524440.1\|171288_171561_-\|holin	phage holin family protein	K4NX91	Burkholderia_phage	8.8e-42	100.0
WP_004524439.1\|171562_171907_-	membrane protein	K4NZQ3	Burkholderia_phage	2.9e-50	100.0
WP_004524438.1\|171921_172128_-\|tail	tail protein X	K4PAW7	Burkholderia_phage	2.4e-31	100.0
WP_004552636.1\|172124_172376_-	hypothetical protein	K4NXI9	Burkholderia_phage	8.4e-39	98.8
WP_004556517.1\|172375_172855_-\|head	head completion/stabilization protein	A4JWU5	Burkholderia_virus	2.2e-80	99.4
WP_009897056.1\|172954_173644_-\|terminase	terminase endonuclease subunit	A4JWP8	Burkholderia_virus	5.6e-117	99.1
WP_011204764.1\|173640_174651_-\|capsid	phage major capsid protein, P2 family	K4NZP8	Burkholderia_phage	8.3e-186	97.9
WP_004532870.1\|174684_175494_-\|capsid	GPO family capsid scaffolding protein	A4JWU8	Burkholderia_virus	3.2e-148	100.0
WP_011204765.1\|175637_177407_+\|terminase	terminase ATPase subunit family protein	A4JWU9	Burkholderia_virus	0.0e+00	99.8
WP_011204766.1\|177403_178459_+\|portal	phage portal protein	A4JWQ2	Burkholderia_virus	1.3e-205	99.4
WP_004202809.1\|178502_178859_-	putative addiction module antidote protein	A4JWV1	Burkholderia_virus	3.9e-42	100.0
WP_006027262.1\|178861_179158_-	type II toxin-antitoxin system RelE/ParE family toxin	A4JWV2	Burkholderia_virus	5.6e-50	99.0
WP_038782825.1\|179987_180551_-	hypothetical protein	NA	NA	NA	NA
WP_162486661.1\|180547_180904_-	hypothetical protein	NA	NA	NA	NA
WP_004190026.1\|182071_182806_+	7-cyano-7-deazaguanine synthase QueC	A0A1B0Z0B4	Vibrio_phage	1.6e-50	42.5
WP_004189241.1\|182899_183532_+	7-carboxy-7-deazaguanine synthase	R4TAH8	Halovirus	2.1e-06	30.9
WP_004189793.1\|183551_184004_+	6-carboxytetrahydropterin synthase QueD	A0A088FAL2	Vibrio_phage	7.6e-14	30.8
WP_004189570.1\|184423_185209_+	2-dehydro-3-deoxyglucarate aldolase	NA	NA	NA	NA
WP_004552446.1\|185205_185982_+	sel1 repeat family protein	NA	NA	NA	NA
WP_004189171.1\|186310_187459_-	rod shape-determining protein RodA	NA	NA	NA	NA
WP_011204769.1\|187470_189927_-	penicillin-binding protein 2	NA	NA	NA	NA
WP_004523092.1\|190110_190623_-	rod shape-determining protein MreD	NA	NA	NA	NA
WP_004189331.1\|190619_191693_-	rod shape-determining protein MreC	NA	NA	NA	NA
WP_004189550.1\|191812_192856_-	rod shape-determining protein	NA	NA	NA	NA
WP_004189769.1\|193220_193520_+\|tRNA	Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatC	NA	NA	NA	NA
WP_004525859.1\|193632_195123_+\|tRNA	Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatA	NA	NA	NA	NA
WP_004552444.1\|195125_196598_+\|tRNA	Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatB	NA	NA	NA	NA
WP_004189747.1\|196724_197564_+	hypothetical protein	NA	NA	NA	NA
WP_004190029.1\|197595_198366_+	exodeoxyribonuclease III	R4TWA8	Phaeocystis_globosa_virus	3.4e-30	33.8
WP_004534096.1\|198654_199719_-	NAD(P)-dependent alcohol dehydrogenase	A0A2K9L339	Tupanvirus	1.3e-80	45.8
WP_004531039.1\|199930_200875_+	AraC family transcriptional regulator	NA	NA	NA	NA
WP_004525863.1\|201248_202301_-	M48 family metallopeptidase	NA	NA	NA	NA
WP_004523086.1\|202290_203604_-	AmpG family muropeptide MFS transporter	NA	NA	NA	NA
WP_004545692.1\|203615_204230_-	methionine biosynthesis protein MetW	NA	NA	NA	NA
WP_004198305.1\|204226_205372_-	homoserine O-acetyltransferase	NA	NA	NA	NA
WP_004548171.1\|205720_206410_-	nucleoid occlusion factor SlmA	NA	NA	NA	NA
WP_004198307.1\|206376_207180_-	pyrimidine 5'-nucleotidase	NA	NA	NA	NA
WP_004200214.1\|207176_208076_-	acetylglutamate kinase	NA	NA	NA	NA
WP_004198312.1\|208400_208652_+	cysteine-rich CWC family protein	NA	NA	NA	NA
WP_004198314.1\|208669_209950_+	HAMP domain-containing histidine kinase	NA	NA	NA	NA
WP_004198315.1\|209969_210512_+	response regulator transcription factor	NA	NA	NA	NA
WP_004523084.1\|210929_212273_-\|protease	ATP-dependent protease ATPase subunit HslU	A0A191ZC11	Erwinia_phage	5.3e-39	28.4
WP_004203414.1\|212282_212819_-\|protease	ATP-dependent protease subunit HslV	NA	NA	NA	NA

DBSCAN-SWA_2

1039747 : 1050714

Streptococcus_phage(16.67%)

protease

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_004197486.1\|1039747_1041862_-	elongation factor G	E4ZFJ7	Streptococcus_phage	5.8e-56	26.7
WP_004530837.1\|1042162_1042672_-	DUF192 domain-containing protein	A0A1B1IUW8	uncultured_Mediterranean_phage	5.5e-13	41.2
WP_071810810.1\|1042863_1043082_-	hypothetical protein	NA	NA	NA	NA
WP_004189780.1\|1043344_1043923_-	pseudouridine synthase	NA	NA	NA	NA
WP_004189552.1\|1044190_1045450_+	NADP-dependent isocitrate dehydrogenase	Q77Z09	Phage_21	5.2e-12	63.0
WP_004189626.1\|1045422_1045605_-	hypothetical protein	NA	NA	NA	NA
WP_011204917.1\|1045617_1047237_+	multicopper oxidase family protein	NA	NA	NA	NA
WP_004196460.1\|1047366_1047570_-	cold-shock protein	A0A2H4N7Y6	Lake_Baikal_phage	6.8e-23	81.8
WP_004194131.1\|1048102_1048417_+\|protease	ATP-dependent Clp protease adapter ClpS	A0A218MMY6	uncultured_virus	4.4e-13	44.6
WP_004196461.1\|1048413_1050714_+\|protease	ATP-dependent Clp protease ATP-binding subunit ClpA	A0A223W0B1	Agrobacterium_phage	5.1e-167	42.1

DBSCAN-SWA_3

1614441 : 1622780

Ralstonia_virus(42.86%)

integrase

attL 1608720:1608735|attR 1617294:1617309

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
1608720:1608735	attL	NA	NA	NA	NA
WP_071810706.1\|1614441_1614870_-\|integrase	tyrosine-type recombinase/integrase	A0A1S5NNJ1	Burkholderia_phage	4.6e-21	47.4
WP_004521809.1\|1615047_1615761_-	immunity 52 family protein	A4PE26	Ralstonia_virus	1.5e-32	43.3
WP_014696823.1\|1615769_1616372_-	hypothetical protein	NA	NA	NA	NA
WP_004546986.1\|1616713_1617217_-	DUF4123 domain-containing protein	A4PE24	Ralstonia_virus	3.0e-19	40.1
WP_004534827.1\|1617219_1617642_-	PAAR domain-containing protein	A4JWV5	Burkholderia_virus	4.9e-15	48.3
1617294:1617309	attR	NA	NA	NA	NA
WP_011205000.1\|1617922_1618318_-	hypothetical protein	NA	NA	NA	NA
WP_004535561.1\|1618670_1618799_+	hypothetical protein	Q8W6S4	Burkholderia_virus	3.4e-12	78.6
WP_004527234.1\|1618834_1619068_-	immunity 52 family protein	A4PE26	Ralstonia_virus	4.3e-13	60.6
WP_004550288.1\|1619143_1619605_-	avidin/streptavidin family protein	NA	NA	NA	NA
WP_004534930.1\|1620543_1620726_+	hypothetical protein	NA	NA	NA	NA
WP_004193371.1\|1620852_1621476_-	phospholipase D family protein	NA	NA	NA	NA
WP_004192901.1\|1621670_1622780_-	class II histone deacetylase	A0A2K9L2T7	Tupanvirus	7.8e-36	31.0

DBSCAN-SWA_4

3017357 : 3026206

Tanapox_virus(16.67%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_004533881.1\|3017357_3018200_+	alpha/beta hydrolase	A7XCB7	Tanapox_virus	2.1e-17	26.6
WP_004533906.1\|3018542_3019466_-	histone deacetylase family protein	A0A2K9KZC4	Tupanvirus	8.4e-44	36.5
WP_045606458.1\|3019644_3020946_+	lytic murein transglycosylase B	NA	NA	NA	NA
WP_004550116.1\|3021172_3022075_-	cysteine synthase CysM	A0A1X9I5F1	Streptococcus_phage	3.3e-53	39.9
WP_004189725.1\|3022410_3022728_-	helix-hairpin-helix domain-containing protein	NA	NA	NA	NA
WP_004544120.1\|3022799_3023792_-	ADP-glyceromanno-heptose 6-epimerase	R9S880	Prochlorococcus_phage	9.1e-28	30.9
WP_009921652.1\|3023850_3024774_-	D-glycero-beta-D-manno-heptose-7-phosphate kinase	A0A2H4N7X4	Lake_Baikal_phage	1.3e-15	27.1
WP_004527508.1\|3024805_3026206_-	UDP-glucose/GDP-mannose dehydrogenase family protein	A0A127AXI2	Bacillus_phage	1.1e-79	38.5

DBSCAN-SWA_5

3368577 : 3381971

Burkholderia_phage(12.5%)

transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_004554094.1\|3368577_3369798_-\|transposase	ISL3-like element ISBma1 family transposase	A9YX10	Burkholderia_phage	3.0e-238	99.5
WP_004527676.1\|3369942_3370998_-	phosphoribosylformylglycinamidine cyclo-ligase	A0A1D7SEW4	Cyanophage	6.4e-72	44.4
WP_004196484.1\|3371296_3372022_+	DnaA regulatory inactivator Hda	NA	NA	NA	NA
WP_004194213.1\|3372043_3372730_+	HAD-IB family hydrolase	NA	NA	NA	NA
WP_004522151.1\|3372726_3374274_+	polynucleotide adenylyltransferase PcnB	H7BUW3	unidentified_phage	4.3e-24	31.2
WP_004527677.1\|3374310_3374838_+	2-amino-4-hydroxy-6- hydroxymethyldihydropteridine diphosphokinase	NA	NA	NA	NA
WP_004532195.1\|3374834_3375518_+	deoxynucleoside kinase	A0A249XZR7	Enterococcus_phage	2.0e-05	26.0
WP_004194137.1\|3375582_3376398_+	3-methyl-2-oxobutanoate hydroxymethyltransferase	A0A0N7HVJ8	Ostreococcus_lucimarinus_virus	8.8e-37	33.3
WP_004194350.1\|3376581_3378588_-	bifunctional anthranilate synthase component I family protein/class IV aminotransferase	S4VT78	Pandoravirus	9.7e-53	35.0
WP_004522147.1\|3378621_3379752_-	molecular chaperone DnaJ	A0A1V0SBY2	Catovirus	1.7e-22	27.6
WP_004194034.1\|3380018_3381971_-	molecular chaperone DnaK	A0A1V0SH73	Hokovirus	2.7e-148	49.2

DBSCAN-SWA_6

3665715 : 3722107

Pseudomonas_phage(12.5%)

integrase,tRNA,transposase,plate

attL 3669936:3669953|attR 3727490:3727507

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_004521984.1\|3665715_3667014_+\|tRNA	glutamyl-tRNA reductase	NA	NA	NA	NA
WP_004527811.1\|3667080_3668163_+	peptide chain release factor 1	A0A0S4KWG0	Pseudomonas_phage	6.7e-08	46.6
WP_004527812.1\|3668206_3669064_+	peptide chain release factor N(5)-glutamine methyltransferase	NA	NA	NA	NA
WP_004186955.1\|3669143_3669452_+	Grx4 family monothiol glutaredoxin	NA	NA	NA	NA
WP_004521981.1\|3669466_3670063_+	UbiX family flavin prenyltransferase	NA	NA	NA	NA
3669936:3669953	attL	NA	NA	NA	NA
WP_004521980.1\|3670346_3671135_+	dioxygenase	NA	NA	NA	NA
WP_004527813.1\|3671583_3673185_-	APC family permease	NA	NA	NA	NA
WP_004196837.1\|3673618_3673822_+	cold-shock protein	A0A2H4N7Y6	Lake_Baikal_phage	6.3e-21	73.1
WP_004198058.1\|3674008_3675271_-	Hsp70 family protein	NA	NA	NA	NA
WP_004198059.1\|3675932_3676538_-	nitroreductase family protein	NA	NA	NA	NA
WP_004521974.1\|3677023_3678307_-	MFS transporter	NA	NA	NA	NA
WP_004549931.1\|3678465_3679110_+	TetR/AcrR family transcriptional regulator	NA	NA	NA	NA
WP_004527819.1\|3679454_3680078_+	DUF1415 domain-containing protein	NA	NA	NA	NA
WP_004521971.1\|3680162_3681059_-	SAM-dependent methyltransferase	NA	NA	NA	NA
WP_004535007.1\|3681186_3682323_-	class I SAM-dependent methyltransferase	NA	NA	NA	NA
WP_004198068.1\|3682491_3682605_+	hypothetical protein	NA	NA	NA	NA
WP_004521968.1\|3682679_3683798_-	acyltransferase	NA	NA	NA	NA
WP_004527823.1\|3683796_3684276_+	hypothetical protein	NA	NA	NA	NA
WP_004199982.1\|3684235_3684739_-	LEA type 2 family protein	NA	NA	NA	NA
WP_004204896.1\|3685342_3687508_+	peptidase	A0A0P0IY26	Acinetobacter_phage	1.9e-46	27.1
WP_004185238.1\|3688563_3688800_+	hypothetical protein	NA	NA	NA	NA
WP_004204906.1\|3688902_3689133_+	hypothetical protein	NA	NA	NA	NA
WP_004199991.1\|3689748_3691017_+	HlyD family efflux transporter periplasmic adaptor subunit	NA	NA	NA	NA
WP_004545619.1\|3691031_3693293_+	peptidase domain-containing ABC transporter	A0A2R8FG22	Brazilian_cedratvirus	2.3e-10	31.9
WP_009938786.1\|3693289_3694738_+	TolC family protein	NA	NA	NA	NA
WP_004555447.1\|3694947_3695934_-	hypothetical protein	NA	NA	NA	NA
WP_004199998.1\|3696059_3696911_+	M15 family metallopeptidase	NA	NA	NA	NA
WP_004555848.1\|3697189_3701083_+	type VI secretion system membrane subunit TssM	NA	NA	NA	NA
WP_004200003.1\|3701079_3702069_+	type VI secretion system-associated protein TagF	NA	NA	NA	NA
WP_011205261.1\|3702073_3703006_+	OmpA family protein	NA	NA	NA	NA
WP_004549922.1\|3703204_3704326_-	type VI secretion system protein TssA	NA	NA	NA	NA
WP_004549921.1\|3704415_3707085_-	type VI secretion system ATPase TssH	A0A223W0B1	Agrobacterium_phage	1.7e-89	32.1
WP_004200010.1\|3707118_3708219_-\|plate	type VI secretion system baseplate subunit TssG	NA	NA	NA	NA
WP_004527836.1\|3708182_3710021_-\|plate	type VI secretion system baseplate subunit TssF	NA	NA	NA	NA
WP_004204912.1\|3710100_3710583_-\|plate	type VI secretion system baseplate subunit TssE	NA	NA	NA	NA
WP_004527837.1\|3710640_3711144_-	type VI secretion system tube protein Hcp	NA	NA	NA	NA
WP_004521953.1\|3711216_3712707_-	type VI secretion system contractile sheath large subunit	NA	NA	NA	NA
WP_004521952.1\|3712723_3713242_-	type VI secretion system contractile sheath small subunit	NA	NA	NA	NA
WP_004531875.1\|3713278_3713950_-	tetratricopeptide repeat protein	NA	NA	NA	NA
WP_004521950.1\|3714324_3714939_+	type VI secretion system lipoprotein TssJ	NA	NA	NA	NA
WP_004521949.1\|3715047_3716394_+\|plate	type VI secretion system baseplate subunit TssK	NA	NA	NA	NA
WP_004521948.1\|3716390_3717176_+	DotU family type IV/VI secretion system protein	NA	NA	NA	NA
WP_004535002.1\|3717660_3717999_-	DUF4102 domain-containing protein	Q8W6M6	Sinorhizobium_phage	1.2e-16	48.0
WP_009932052.1\|3718433_3719234_+	hypothetical protein	NA	NA	NA	NA
WP_004535005.1\|3719240_3720311_+	ImmA/IrrE family metallo-endopeptidase	NA	NA	NA	NA
WP_038802333.1\|3720593_3721713_+\|transposase	IS3 family transposase	S5WIU1	Leptospira_phage	3.6e-49	39.5
WP_076802946.1\|3721846_3722107_+\|integrase	tyrosine-type recombinase/integrase	C8CLF4	Xylella_phage	2.1e-16	68.1
3727490:3727507	attR	NA	NA	NA	NA

DBSCAN-SWA_7

3966097 : 3971939

Ralstonia_phage(50.0%)

integrase

attL 3964324:3964376|attR 3975871:3975923

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
3964324:3964376	attL	NA	NA	NA	NA
WP_009938955.1\|3966097_3966415_-	transcriptional regulator	A0A088CD40	Shigella_phage	4.3e-16	56.5
WP_009910242.1\|3966422_3966755_-	type II toxin-antitoxin system RelE/ParE family toxin	A0A088CBP5	Shigella_phage	9.8e-19	51.9
WP_162486671.1\|3966796_3967540_-\|integrase	tyrosine-type recombinase/integrase	Q9T1P3	Pseudomonas_phage	3.0e-52	46.2
WP_011205299.1\|3967731_3968511_-	bacteriophage-like protein	A0A1W5LU59	Ralstonia_phage	3.2e-36	42.2
WP_009938959.1\|3968967_3969561_-	hypothetical protein	A0A097ZIG8	Ralstonia_phage	7.6e-06	41.7
WP_011205301.1\|3969660_3971037_-	bacteriophage-related lipoprotein	NA	NA	NA	NA
WP_009938961.1\|3971033_3971939_-	AAA family ATPase	Q6UAZ2	Ralstonia_phage	4.9e-28	37.7
3975871:3975923	attR	NA	NA	NA	NA

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. NC_006351

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CRISPR-Cas detection and classification

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Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection

2. NC_006350

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CRISPR-Cas detection and classification

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Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection