CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NC_006349	Burkholderia mallei ATCC 23344 chromosome 2, complete sequence	3 crisprs	csa3,cas3	0	0	4	0
NC_006348	Burkholderia mallei ATCC 23344 chromosome 1, complete sequence	1 crisprs	csa3,DEDDh,DinG,WYL,cas3	0	1	10	0

Results visualization

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CRISPR-Cas detection and classification

Crispr_ID: NC_006349_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_006349_1

124506-124598

Orphan

Consensus_repeat	Method
TCGCCGCCGCGCGCGACGACGCGC	CRISPRCasFinder

1 spacers

The CRISPR arrays of NC_006349_1

>merge|NC_006349|1|124506-124598|CRISPRCasFinder
TCGCCGCCGCGCGCGACGACGCGCTGAAGGACGCGCTCGCGCAGGCCGCCGCCGAGCGCGAGCGGCTGATCGCCGCCGCGCGCGCCGACGCGC

>NC_006349|1|1|124506-124598|CRISPRCasFinder
TCGCCGCCGCGCGCGACGACGCGC	TGAAGGACGCGCTCGCGCAGGCCGCCGCCGAGCGCGAGCGGCTGA
TCGCCGCCGCGCGCGCCGACGCGC

Protein	Signature genes	Signature genes Name	Protein_function
NC_006349.2\|WP_004188377.1\|135839_139055_-\|ATP-binding-cassette-domain-containing-protein	unknown	unknown	gnl\|CDD\|224054
NC_006349.2\|WP_004187376.1\|132727_134563_-\|response-regulator	unknown	unknown	gnl\|CDD\|237425
NC_006349.2\|WP_164929804.1\|113612_115130_+\|hexose-kinase	unknown	unknown	gnl\|CDD\|238570
NC_006349.2\|WP_004188594.1\|116937_118341_-\|bifunctional-enoyl-CoA-hydratase/phosphate-acetyltransferase	unknown	unknown	gnl\|CDD\|236180
NC_006349.2\|WP_004188840.1\|118351_120145_-\|polyhydroxyalkanoic-acid-synthase	unknown	unknown	gnl\|CDD\|213656
NC_006349.2\|WP_044302747.1\|130779_132384_+\|methyl-accepting-chemotaxis-protein	unknown	unknown	gnl\|CDD\|185008
NC_006349.2\|WP_004187687.1\|129195_129711_+\|hypothetical-protein	unknown	unknown	unknown
NC_006349.2\|WP_004188073.1\|120505_122110_+\|F0F1-ATP-synthase-subunit-beta	unknown	unknown	gnl\|CDD\|183615
NC_006349.2\|WP_004188537.1\|140117_141644_-\|efflux-transporter-outer-membrane-subunit	unknown	unknown	gnl\|CDD\|182103
NC_006349.2\|WP_004188303.1\|127042_127891_+\|F0F1-ATP-synthase-subunit-gamma	unknown	unknown	gnl\|CDD\|376304
NC_006349.2\|WP_004187158.1\|129768_130278_-\|hypothetical-protein	unknown	unknown	unknown
NC_006349.2\|WP_004198321.1\|128105_129131_+\|alcohol-dehydrogenase-AdhP	unknown	unknown	gnl\|CDD\|176257
NC_006349.2\|WP_004187193.1\|124038_124287_+\|F0F1-ATP-synthase-subunit-C	unknown	unknown	gnl\|CDD\|184067
NC_006349.2\|WP_004188438.1\|122551_123043_+\|AtpZ/AtpI-family-protein	unknown	unknown	gnl\|CDD\|378198
NC_006349.2\|WP_004187346.1\|123340_124042_+\|F0F1-ATP-synthase-subunit-A	unknown	unknown	gnl\|CDD\|237383
NC_006349.2\|WP_004188525.1\|134712_135837_-\|ABC-transporter-permease	unknown	unknown	gnl\|CDD\|223912
NC_006349.2\|WP_004188458.1\|115762_116941_-\|acetate/propionate-family-kinase	unknown	unknown	gnl\|CDD\|235922
NC_006349.2\|WP_004201694.1\|123035_123344_+\|membrane-protein	unknown	unknown	gnl\|CDD\|274462
NC_006349.2\|WP_004188355.1\|125033_127046_+\|F0F1-ATP-synthase-subunit-alpha	unknown	unknown	gnl\|CDD\|183987
NC_006349.2\|WP_004188221.1\|122099_122555_+\|F0F1-ATP-synthase-subunit-epsilon	unknown	unknown	gnl\|CDD\|184057

Protein	Function_ID	Function_description	E-value
NC_006349.2\|WP_004188377.1\|135839_139055_-\|ATP-binding-cassette-domain-containing-protein	gnl\|CDD\|224054	COG1131, CcmA, ABC-type multidrug transport system, ATPase component [Defense mechanisms].	1.59115e-92
NC_006349.2\|WP_004187376.1\|132727_134563_-\|response-regulator	gnl\|CDD\|237425	PRK13557, PRK13557, histidine kinase; Provisional.	2.51413e-132
NC_006349.2\|WP_164929804.1\|113612_115130_+\|hexose-kinase	gnl\|CDD\|238570	cd01164, FruK_PfkB_like, 1-phosphofructokinase (FruK), minor 6-phosphofructokinase (pfkB) and related sugar kinases. FruK plays an important role in the predominant pathway for fructose utilisation.This group also contains tagatose-6-phophate kinase, an enzyme of the tagatose 6-phosphate pathway, which responsible for breakdown of the galactose moiety during lactose metabolism by bacteria such as L. lactis.	3.18235e-109
NC_006349.2\|WP_004188594.1\|116937_118341_-\|bifunctional-enoyl-CoA-hydratase/phosphate-acetyltransferase	gnl\|CDD\|236180	PRK08190, PRK08190, bifunctional enoyl-CoA hydratase/phosphate acetyltransferase; Validated.	0
NC_006349.2\|WP_004188840.1\|118351_120145_-\|polyhydroxyalkanoic-acid-synthase	gnl\|CDD\|213656	TIGR01838, Poly-beta-hydroxybutyrate_polymerase, poly(R)-hydroxyalkanoic acid synthase, class I. This model represents the class I subfamily of poly(R)-hydroxyalkanoate synthases, which polymerizes hydroxyacyl-CoAs with three to five carbons in the hydroxyacyl backbone into aliphatic esters termed poly(R)-hydroxyalkanoic acids. These polymers accumulate as carbon and energy storage inclusions in many species and can amount to 90 percent of the dry weight of cell. [Fatty acid and phospholipid metabolism, Biosynthesis].	6.3979e-179
NC_006349.2\|WP_044302747.1\|130779_132384_+\|methyl-accepting-chemotaxis-protein	gnl\|CDD\|185008	PRK15048, PRK15048, methyl-accepting chemotaxis protein II; Provisional.	2.56608e-79
NC_006349.2\|WP_004188073.1\|120505_122110_+\|F0F1-ATP-synthase-subunit-beta	gnl\|CDD\|183615	PRK12597, PRK12597, F0F1 ATP synthase subunit beta; Provisional.	0
NC_006349.2\|WP_004188537.1\|140117_141644_-\|efflux-transporter-outer-membrane-subunit	gnl\|CDD\|182103	PRK09837, PRK09837, Cu(I)/Ag(I) efflux RND transporter outer membrane protein.	7.30998e-99
NC_006349.2\|WP_004188303.1\|127042_127891_+\|F0F1-ATP-synthase-subunit-gamma	gnl\|CDD\|376304	pfam00231, ATP-synt, ATP synthase.	1.10329e-32
NC_006349.2\|WP_004198321.1\|128105_129131_+\|alcohol-dehydrogenase-AdhP	gnl\|CDD\|176257	cd08297, CAD3, Cinnamyl alcohol dehydrogenases (CAD). These alcohol dehydrogenases are related to the cinnamyl alcohol dehydrogenases (CAD), members of the medium chain dehydrogenase/reductase family. NAD(P)(H)-dependent oxidoreductases are the major enzymes in the interconversion of alcohols and aldehydes, or ketones. Cinnamyl alcohol dehydrogenases (CAD) reduce cinnamaldehydes to cinnamyl alcohols in the last step of monolignal metabolism in plant cells walls. CAD binds 2 zinc ions and is NADPH- dependent. CAD family members are also found in non-plant species, e.g. in yeast where they have an aldehyde reductase activity. The medium chain dehydrogenases/reductase (MDR)/zinc-dependent alcohol dehydrogenase-like family, which contains the zinc-dependent alcohol dehydrogenase (ADH-Zn) and related proteins, is a diverse group of proteins related to the first identified member, class I mammalian ADH. MDRs display a broad range of activities and are distinguished from the smaller short chain dehydrogenases (~ 250 amino acids vs. the ~ 350 amino acids of the MDR). The MDR proteins have 2 domains: a C-terminal NAD(P) binding-Rossmann fold domain of a beta-alpha form and an N-terminal catalytic domain with distant homology to GroES. The MDR group contains a host of activities, including the founding alcohol dehydrogenase (ADH), quinone reductase, sorbitol dehydrogenase, formaldehyde dehydrogenase, butanediol DH, ketose reductase, cinnamyl reductase, and numerous others. The zinc-dependent alcohol dehydrogenases (ADHs) catalyze the NAD(P)(H)-dependent interconversion of alcohols to aldehydes or ketones. Active site zinc has a catalytic role, while structural zinc aids in stability. ADH-like proteins typically form dimers (typically higher plants, mammals) or tetramers (yeast, bacteria), and generally have 2 tightly bound zinc atoms per subunit. The active site zinc is coordinated by a histidine, two cysteines, and a water molecule. The second zinc seems to play a structural role, affects subunit interactions, and is typically coordinated by 4 cysteines.	0
NC_006349.2\|WP_004187193.1\|124038_124287_+\|F0F1-ATP-synthase-subunit-C	gnl\|CDD\|184067	PRK13468, PRK13468, F0F1 ATP synthase subunit C; Provisional.	4.45015e-37
NC_006349.2\|WP_004188438.1\|122551_123043_+\|AtpZ/AtpI-family-protein	gnl\|CDD\|378198	pfam09527, ATPase_gene1, Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter. This model represents a protein found encoded in F1F0-ATPase operons in several genomes, including Methanosarcina barkeri (archaeal) and Chlorobium tepidum (bacterial). It is a small protein (about 100 amino acids) with long hydrophobic stretches and is presumed to be a subunit of the enzyme. It carries two transmembrane helices and is a magnesium or calcium uniporter. The atp operon of alkaliphilic Bacillus pseudofirmus OF4, as in most prokaryotes, contains the eight structural genes for the F-ATPase (ATP synthase), which are preceded by an atpI gene that encodes a membrane protein with 2 TMSs. A tenth gene, atpZ, has been found in this operon, which is upstream of and overlapping with atpI.	7.77353e-17
NC_006349.2\|WP_004187346.1\|123340_124042_+\|F0F1-ATP-synthase-subunit-A	gnl\|CDD\|237383	PRK13421, PRK13421, F0F1 ATP synthase subunit A; Provisional.	1.54059e-122
NC_006349.2\|WP_004188525.1\|134712_135837_-\|ABC-transporter-permease	gnl\|CDD\|223912	COG0842, COG0842, ABC-type multidrug transport system, permease component [Defense mechanisms].	6.54035e-26
NC_006349.2\|WP_004188458.1\|115762_116941_-\|acetate/propionate-family-kinase	gnl\|CDD\|235922	PRK07058, PRK07058, acetate/propionate family kinase.	0
NC_006349.2\|WP_004201694.1\|123035_123344_+\|membrane-protein	gnl\|CDD\|274462	TIGR03165, F1F0_chp_2, F1/F0 ATPase, Methanosarcina type, subunit 2. Members of this protein family are uncharacterized, highly hydrophobic proteins encoded in the middle of apparent F1/F0 ATPase operons. We note, however, that this protein is both broadly and sparsely distributed. It is found in about only about two percent of microbial genomes sequenced, with the first ten examples found coming from the Euryarchaeota, Chlorobia, Betaproteobacteria, Deltaproteobacteria, and Planctomycetes. In most of these species, surrounding operon appears to represent a second F1/F0 ATPase system, and the member proteins belong to subfamilies with the same phylogenetic distribution as the current protein family.	3.23546e-10
NC_006349.2\|WP_004188355.1\|125033_127046_+\|F0F1-ATP-synthase-subunit-alpha	gnl\|CDD\|183987	PRK13343, PRK13343, F0F1 ATP synthase subunit alpha; Provisional.	0
NC_006349.2\|WP_004188221.1\|122099_122555_+\|F0F1-ATP-synthase-subunit-epsilon	gnl\|CDD\|184057	PRK13447, PRK13447, F0F1 ATP synthase subunit epsilon; Provisional.	4.44077e-63

>NC_006349.2|WP_004187193.1|124038_124287_+|F0F1-ATP-synthase-subunit-C
MNNLIEVVSIAAAALAVSFGAIGPALAEGRAVGAAMDAIARQPDASGTVSRTLFVGLAMIETMAIYCLVVALLLLFANPFVK
>NC_006349.2|WP_004187346.1|123340_124042_+|F0F1-ATP-synthase-subunit-A
MNASPLSTVPLFSVGPVGISAPVLATWAIMAVLVALALVARRRLSVDAPSRLQSVLELFVATVDAQIADTMQTPPARYRALIGTIFVLVFCANGASLVPGVEPPTAHLETDAALALVVLAATLYYGVRARGVRGYLATFAEPTWVMIPLNVVEQLTRTFSLIVRLFGNVMSGVFVIGIVLSLAGLFVPIPLMALDLLTGTVQAYIFMVLSMVFIGAAVSGDETSAPRRGQENT
>NC_006349.2|WP_004201694.1|123035_123344_+|membrane-protein
MIEMWETARASFDGIAAAIGLALGFAAGACHFVSLGWNSRLFVAGRAGVALALQFARVALAVAVLVVLARAGFGMLVAGSAGFFAARAIAVRRAAALTGARR
>NC_006349.2|WP_004188438.1|122551_123043_+|AtpZ/AtpI-family-protein
MMKRRPPEVKREARDDAARGDARHAGAGAAPDDPRGAARRDPSPGSRAARGGATHPAARAAEPAAPKPAADRVERAAHTAAARAARGARDPEPSLGRRLAQIGVLGWTIVAPTLAALALGRWLDRMFATRVFFSAPLLMLGAALGLWLAWRWMKAQQHGDRDD
>NC_006349.2|WP_004188221.1|122099_122555_+|F0F1-ATP-synthase-subunit-epsilon
MGAELRVTIATPARVCVDDLPIVSLRAEDASGAFGIRAGHVDFVTLLRASVVRWRTADGATHYAALDGGVLRVTRGARIEIACRDAVLGESLAELEAVVRGVRATQLDEKRRARVDETRLHAQAVRRLLTYLRPEHAKDGVHAPLKPETLE
>NC_006349.2|WP_004188073.1|120505_122110_+|F0F1-ATP-synthase-subunit-beta
MADPQATNGTGAVCAERDASDVGDVSDVGDARDEGAGRVVAVRGAVVDVAFDGGALPALNEALTIPVDGAAPILAEVHAHLSDAAVRALALGPTGGLRRGAAVRATGGPIRVPVGDAVLGRLLSVTGAPGDDGAALAADVERRPIHRGAPLLAEQKSANALFATGIKVIDLLAPLAQGGKAAMFGGAGVGKTVFVMELIHAMVERYRGISVFAGIGERSREGHEMLLDMRGSGVLGRTVLVYGQMNEPPGARWRVPLTALAIAEYFRDERAQNVLLLMDNVFRFVQAGAEVSGLLGRLPSRVGYQPTLASEVAALQERIASVEGAAVTAIEAVYVPADDFTDPAVTAIAAHVDSMVVLSRAMAAEGMYPAIDPVASSSILLDPLVVGEAHVEVAIEVRRVIEHYRELQDVIALLGIDELGADDRRLVGRARRLQRFLTQPFAVTEAFTGQAGASVEIADTIAGCRAILRGDCDDWRESSLYMVGTLDDARRKEAAAREADARREAAAAASGAGPGTTSDPASGSAEPQGARHGR
>NC_006349.2|WP_004188840.1|118351_120145_-|polyhydroxyalkanoic-acid-synthase
MDTRHAPESGAPDAPLPAHPPASYAPESPYRIFDLAKEASVAKLTSGLSPASLQLALADWLIHLAAAPGKRAELATLALRHAALLGQYLLEAATGRTPAAPAQPSPGDRRFRAGAWQLEPYRFWHQSFLLAEQWWRAATRDVPGVSPHHEDVVAFSARQMLDTFAPANYVATNPEIAQRTALTGGANLAQGVWNYLDDVRRLITKQPPAGAEQFELGRNLATTPGRVVFRNHLIELLQYSPTTPDVYAQPVLIVPAWIMKYYILDLSAHNSLIRYLVGEGHTVFCISWRNVDASDRDLSLDDYRKLGVMDALDTIGAIVPGEKIHATGYCLGGTLLSIAAAAMANTGDDRLASITLLAAQTDFAEPGELQLFIDDSEIHFLESMMWERGYLGAHQMAGSFQLLMSNDLIWSRVIHDYLLGERTPMIDLMAWNADSTRMPYRMHSEYLRHLFLDNDLATNRYVIDGQTVSVHNIRAPFFVVGTEHDHIAPWRSVYKIHYLSGSDVTFVLTAGGHNAGIVSEPGHAKRHYRMKMTAAAAPSISPDEWLAGATDFEGSWWPAWHAWLARHSSPQRVAPPPLGKPGAHTLGDAPGTYVFQK
>NC_006349.2|WP_004188594.1|116937_118341_-|bifunctional-enoyl-CoA-hydratase/phosphate-acetyltransferase
MDREILQNRPFDSLAIGDSASLVRTASRDDIDLFAAMSGDVNPAHLDAAFAAHDLFGHVVVHGMWTGALVSAVLGTKLPGPGTIYLDQTLEFRHPVAPGDTITATVTVAEKRPEKRIVLLDTRCTNQDGHVVLRGTATVIAPDTPITWERVPGPEVAVRRHDRYETFVRDAREQPPLRTAIVHPCSPDALRAAIDARDANLIEPILIGPQAKIRAIADAAGVDLAGVPIEAVEHSHAAAARAVEMGGAGEVAALMKGSLHTDELLAAVIGPASRLRTERRISHVYAMDVPAYPKPLLITDAAINIAPTLEQKRDICQNAVDLLHVLGVERPRVAVLAAVETVNPKMPSTLDAAALTVMAARGQIAGAIVDGPLAFDNAVSAVAAMSKGIASPVAGDADVLLVPDLEAGNMLAKQLMYFAGADAAGLVLGTRLPIILTSRADSLRVRIASAALAKLVAERTRAGALAS
>NC_006349.2|WP_004188458.1|115762_116941_-|acetate/propionate-family-kinase
MSEPLLLTFNAGSSTLKIGLYSVANGEPAPLGRGKIDFNRAPLQFEYANGGEAHAVPLAAPVTDDLHAVLDEALGWIDAHLSVHELVSVGHRVVHGGDTFDGPVRIDERTLDAIAALVPLAPLHQPQSVRLIRALRHVRPHLPQVASFDTAFHRTQSDLVRRFALPRALFDAGIKRYGFHGLSYRYVAGRLRERHPSIARGKVVAAHLGSGASLCALDAGVSRDTSMGFSTLDGIPMATRCGALDAGVVLHLQKTLGRTLDDVEQMLYHRSGLLGVSGVSGDARALLADPSAGARDALELFAFRIAGETARLAATLGGLDALVFTAGIGEHQPQTRAAVCERLRWLSVELDAHANARNAETVSRDGSRVAVLVVPTDEEQVIARDAASVLHA
>NC_006349.2|WP_164929804.1|113612_115130_+|hexose-kinase
MRGACASRAMFDTGGKRQAASGKRQAASGKRQAASGKRQAASGKQQAASSKQQAASSKQQAASSKQQAASSKQQAASSKQQAASSKQQAASSKQQAASSKQQAASSKQQAASSKQQAASSKQQAASSKQQAASSKQQAASSSRPAPVLMVRRRIERKHCGACPPRSTREPRTRASRCVVFPSRIPTLKPNVTMPEIVTLTPNPAIDVATCVERVTDTRKLRCGPARRDPGGGGINVARVLTRLGADCSAVYLAGGGTGLALRGLLADEGVRAHGIDIAGETRENFSVLETSTGREFRFVLPGPALAAHEWPRCVEALGRLADASRYLVMSGSLPPGMPDDCYARLARRASARGVRTVVDTSGPALAAALDAGVYLVKPSLGELRALTGLPLEDDGARLAAARAIVAGGRAQIVALTLGDAGALVVSRDDAVRLPGVKVAVRSAIGAGDSFVAGLVAALNRGANVADAARHALAAASASLLSTGPALGTKEDIARIYRELPGTIDA
>NC_006349.2|WP_004188355.1|125033_127046_+|F0F1-ATP-synthase-subunit-alpha
MTPTPDAPAAADAATGAGWLARRRGALARVALAPIAQAIGRVERVADGIAFVSGLEDTMLNEVLRFEGGVTGFAHTLDEDLISVVLLDPDAGVRAQTAVARTGAVLEVPAGPQLLGRVVDPLGRPLDGGAPLDAAHTLPIERAAPAIIERDLVSEPLDTGVLIVDALFTIGRGQRELIIGDRATGKTSLAIDAIVNQRHSDVICVYVAIGQRASAVRRVIDAVRRYGAPERCVFVVAPAACAPGLQWIAPFAGFSIAEYFRDRGQHALVVVDDLTKHAATHRELALLTREPPGREAYPGDIFYVHARLLERAAKLSAALGGGSLSALPIAETDAGNLAAYIPTNLISITDGQIVLDSALFAANQRPAVDVGLSVSRVGGKAQHPALRAASGRLRLDYAQFLELEAFTRFGGLTDARLRAQITRGERIRALITQPRFRALRTLDEVVLLKALAAGTLDAMSPDLVAPLRERLPAWLDARIAALTPALAPPRDWLADDAALDALAESVGELIERIAADAARRATAGMPAEDAAGDIGGAFGGEQARGDADRDADHGANREVSREVSPEASREVSREVSREVSHEADRDAAADAARVAGRAPGRAEPDRAVPRAMPDGPPRAQADGDRASASRPPPDARGDAARTAPSPQGGADANVNADANVDAEAEARHKR
>NC_006349.2|WP_004188303.1|127042_127891_+|F0F1-ATP-synthase-subunit-gamma
MSDKLAAIEARTDTARQLQTVIGAMQGVAAARAHEAQQRLPGIRASAATVGAAIGDALSAGARSGETAAGARAAPRARFVVVLCSEQGFVGAYNAQLIEHATRPGPSVSREYMMVGSRGAMLADAGGVPLVWRTPMAARADDVVHLANRITDALYAHLAKRGAQPVSIVHAMPGGAARLEVTERRLLPFDYARFDTAPRAQPPLVHLPPATLLAELAQAYVFVELCEAAMLAFAAENEARTRAMIAARESVERALGDLLQAYRIARQDEITADIVELAASGL
>NC_006349.2|WP_004198321.1|128105_129131_+|alcohol-dehydrogenase-AdhP
MAQYMKAAVVHAFGEPLRIEEVPVPTPGAGQILVNVKASGVCHTDLHAADGDWPVKPTLPFIPGHEGVGFVAAVGEGVRHVKEGDRVGVPWLYTACGHCEYCQTGWETLCHEQQNTGYSVNGSYAEYVLADPNYVGHLPSNVAFDEIAPILCAGVTVYKGIRVTDTRPGQWIAISGIGGLGHVAVQYAKAMGLHVVAVDVAPQKLELARKLGATFVVDASKDDPAAVIQKEIGGVHGVLVTAVSRGAFAQALGMVRRGGTVSLNGLPPGDFPLPIFSTVLNGITVRGSIVGTRRDLQESLDFAAEGLVRAHIHRDKLEHINGVFSALREGKVDGRIVLTGQ
>NC_006349.2|WP_004187687.1|129195_129711_+|hypothetical-protein
MRRAMRGAGRASPSRARRYENVSKEPNTHREAGAPVHRYRLQVRNMNGECRTYELRLSSLDDGYTLEIDEWLNFPDTHLGDVTPVHVSRPVQFAVPAHEFYRRRRAFRTELIESVAAALRAGEVVRMRDSPDEYPGGHAGNPWVNWIRADLRANPGGRPPPVGDDMQDLIH
>NC_006349.2|WP_004187158.1|129768_130278_-|hypothetical-protein
MRRIYFLLPDADTARAIVDELLLKRIEWRHIHVVANDRVPLENLPEASIAQSSDLLPALARGTAADGVTGALAGLAAIAFPPAGLTIAGGAVVAFAIAGAGFGAWVSTMIGVSVPNTRLKHFEDAVDNGELLMMIDVHRDRVEEIEALVKQHHPNAHLEGTDPTIPAFP
>NC_006349.2|WP_044302747.1|130779_132384_+|methyl-accepting-chemotaxis-protein
MAPFHRRTTRNARTPTLSFRQKLWLPLVISLIALLLVSISSAWLSYQTRMEERRNDLTNVAHVGLSIVREYAALAQRGVLTDAQARKEALERLRSVRYGSDGYFIVIDSSPRMIMHPIKPDTVGKDLRHVADADGRHHYLTFASVAQSPQGGFVDYVFAHPNAHPAKAVDKLGYVIRYAPWDWIISTGAYIDDIQAAFAKSLCLSAGVFALLAALLALSVVYTNRGIERMIGGDPRIAAHMAGVIASGDLATPFATRREDRSSLMFAISQMRDALANAVAQIRASAGYVATTAGEIADSNMDLSSHTECQATALQQAASSMQRLTERVRDTADRARAASELAGSAARITDRGGDMVVRVVAAMNDIRAESRKMVDIIGVIEGIAFQTNILALNAAVEAARAGNEGRGFAVVASEVRVLAQRSASAAKDIRALIGRAAERVGNGAELVEATGATIGEAQHAICRVTGIVQDIAAAATDQSQGLEQINAAVSQMDSVTRRNATLVEHAAIAAQSLNEQSRCLQDAVAAFRTEALGC
>NC_006349.2|WP_004187376.1|132727_134563_-|response-regulator
MHVEVFAQHPSCPGWHGEMARRIRAFDWSATELGPLERWPASLVAAVRTVLASPVPLVMLWGASGYMLYNDAYAAFAGGRHPYLLGQPVELGWPEVADFNRNVMRTCLAGGALSYRDKALVLLRNGRPEEVWMDLYYSPLAGDDGAPAGVLAVVVETTERVLAARHRDRAKAALHETNAELRRLTETLEQRVADAITERASIEEQLRQAQKMEAIGSLTGGIAHDFNNVLQVVSSNLQMLSAELGEDARAQRRIASAANAVARGAQLASHLLAFARRQPLAPAVLDPRGLIDGMREMLHRALGESVHVDADLRDDVWNVLADRHQFENALLNLAINARDAMRGEGTLKITACNIVLEAGRHARRNGLPPGEYVAFDIADNGVGMTPDILERVFEPFFTTKPDGQGTGLGLSMVFGFVKQSGGHTSIESAPGRGTTVRLLLPRCREAPAGEPAAQRRLPAEGGRETILVVEDDADVRLAVVDMLAQLGYKVITASDGEAGLLALESGAPIDLLFTDVIMPGRIKGGELARRAAQRVPPVPVLFTSGYTRDEIFHAGRLDPGVMLLGKPYRRDELAHKVRSVLDAHASARRAHGARHAQADPRAKTAAARVQR
>NC_006349.2|WP_004188525.1|134712_135837_-|ABC-transporter-permease
MRRLAIIYRLGVKELWSLVRDPILLVLIAYTFTASIYSAATARPDTLHMAPIAIIDEDASPLSARIASAFFPPQFALPRMVTLAEADRGMDAGDFTFALDIPPNFQRDVLAGRPAQIQLNVDATRMSQAFTGNGYVQQIVSGEIDDFARRYRANTAPPVDIAMHMRFNPNLDQTWFGSLMEVINNVTLLSMVLTGAALIREREHGTIEHLLVMPVTPGEIMLAKVWSMGLVVACAAAFSLAFVVRGALHVPIEGSVALFVIGMAIHLFATTSMGIFLATLVRSMPQFGMLLVLVLLPLQLLSGSLTPRESMPFAVQNIMLAAPTTHFVEIGQAILYRGAGIETVWRQFLILAVIGTALFLLSLKRFRKTIGQMA
>NC_006349.2|WP_004188377.1|135839_139055_-|ATP-binding-cassette-domain-containing-protein
MSAPSVVRFSDVSLRYGKTVALERITLEIPAGLTIGLIGPDGVGKSSLLALAAGARALQTGAVDALGGDMRSRRHRERVCRRIAYMPQGLGKNLYPTLSVEENLQFFARLFGHDADERRRRIDALTRSTGLFAFLSRPAGKLSGGMKQKLGLCCALIHDPDLLILDEPTTGVDPLARAQFWDLIARIRSERPAMSVIVATAYMDEAQRFDWLIAMDAGRVLATGAPAELLARTGCDSLEAAFIALLPEDERRGHKPVTLEPLRADAQTGTAIEARGLTMRFGDFTAVDHVSFRIRRGEIFGFLGSNGCGKSTTMKMLTGLLPATEGTAQLFGKTVDPKDINTRRRVGYMSQAFSLYSELTVRQNLVLHARLFGVPAAEIDARVDEMARRFGLADIYDMLPDSLPLGMRQRLSLAVAMVHKPELLILDEPTSGVDPVARDSFWQLMIDLARRDRVTIFISTHFMNEAQRCDRISLMHAGRVLASDAPAALVRARGAATLEEAFIGYLVDASAQEAQEAQGGAGERPGAGERAAGESVAGRGAATDGDADGAHARPAAYANGAAQHRAPDADAAGTDVAAETGARDDARTAHAAGHSAGNDVRATVGSEVGSEVASEAGLAASAESGSERGVAHGAERAREPAADAGAAIDVEPGASAESATAAVAPARHAESAATSPRAGNAPAGTPFAAAPAEPPHRAFSAQRALSYMWREMLELRRDPVRATLALIGSLVLMCVIGIGISLDVEDLTYAVLDRDQTELSHDYALNLSGSRYFVERPPIADYAALDRRMRDGELSLAIEIPPNFARDVERGAPAQIGMWIDGAMPQRAETIRGYAIGMHTMWLADKARHRLGVTLAPRAEVVTRYRYNPDVKSLPAMIPAVMPLLLLMLPAMLTALAVVRERELGSILNLYVTPVTRTEFLIGKQVPYVVLAMLNFLLMTMLARIAFDVPVKGSFMTLLLAVLIFNVVATGIGLLASTFTRSQVAAIVMTIIGTMIPTVQFAGLLTPLSSLEGTGRLIGLVYPATYMLSISRGVFNKALSLHELYSQFWPLAACVPVILGATILLLKKQER
>NC_006349.2|WP_004188537.1|140117_141644_-|efflux-transporter-outer-membrane-subunit
MTMRNDARHDERHQRRRGIARRAARHAAALALCAAVSGCLSLAPDYARKPPPVPAAYPAYPGEPGAGSRTLEQLGWRAYFVDPRLQALIETALANNRDLRIAAQRVEQARAAYGIRRADQYPTIAANAAYLRFREPGGLLLPSPIIGELYSASLSEVQWEIDFWGRVRSLKAAALDTFLASDASRRAVTVSLIGQVADAYLALCAYDERLALTNETIASRRDSLRIFRRRYEEGAISKLDLTQSEILLQQAQTLGSQLQQARDVQQHALDLLVGTNAAARTPASLDDASIAPDLAPGLPSELLANRPDVVAAEYQLRAAHANIGAARAAFFPRIALTSSIGTGSTELHNLFASGTAAWNFIPNLSVPIFDAGRNIGNLKLANARRDEALAQYEKTIQTAFRDVADALAARHWLADQVRIAQETLATQAERARLAKLRYDSGAARFLEVLDAQRDLLNAQQQLVQTRRALLASRVALYAALGGRLDEPARDGAAPRPSPEPSAKQGPLS

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Crispr_ID: NC_006349_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_006349_2

1076602-1076764

Orphan

Consensus_repeat	Method
GGCGGGCCGGCCGCCG---------------------------CGCGGGCG	PILER-CR

2 spacers

The CRISPR arrays of NC_006349_2

>merge|NC_006349|2|1076602-1076764|PILER-CR
GGCCGCTCGGCCGCCGCGCGGGCGCGTGTTCCACGTGGCGGCCTGCGCCGTGTCGGCCGCGGCGGCCGTGCGGAGCGGGCCGGCCGCCGCGGCGATGGTGGCCGCGCGGATCACGTGGATCACGTTGACGGCGTTGAACGGCGGGCCGGCCGCCGCGCGGGCG

>NC_006349|2|1|1076602-1076764|PILER-CR
GGCCGCTCGGCCGCCGCGCGGGCG	CGTGTTCCACGTGGCGGCCTGCGCCGTGTCGGCCGCGGCGGCCGTGCGG
AGCGGGCCGGCCGCCGCGGCGATG	GTGGCCGCGCGGATCACGTGGATCACGTTGACGGCGTTGAACGGCGGG
CCGGCCGCCGCGCGGGCG

Protein	Signature genes	Signature genes Name	Protein_function
NC_006349.2\|WP_004197695.1\|1090544_1092242_+\|WD40-repeat-domain-containing-protein	unknown	unknown	gnl\|CDD\|238121
NC_006349.2\|WP_004184915.1\|1089588_1089885_+\|hypothetical-protein	unknown	unknown	unknown
NC_006349.2\|WP_004197872.1\|1069081_1070551_-\|efflux-RND-transporter-periplasmic-adaptor-subunit	unknown	unknown	gnl\|CDD\|273386
NC_006349.2\|WP_004197868.1\|1065106_1065796_-\|heavy-metal-response-regulator-transcription-factor-IrlR	unknown	unknown	gnl\|CDD\|130454
NC_006349.2\|WP_004197879.1\|1073657_1074146_-\|adenosine-specific-kinase	unknown	unknown	gnl\|CDD\|377190
NC_006349.2\|WP_004524134.1\|1072864_1073005_-\|bacteriophage-protein	unknown	unknown	unknown
NC_006349.2\|WP_004199160.1\|1084799_1087901_+\|efflux-RND-transporter-permease-subunit	unknown	unknown	gnl\|CDD\|169983
NC_006349.2\|WP_004266238.1\|1088035_1089574_+\|efflux-RND-transporter-outer-membrane-subunit-OprB	unknown	unknown	gnl\|CDD\|182103
NC_006349.2\|WP_004184876.1\|1083705_1084803_+\|efflux-RND-transporter-periplasmic-adaptor-subunit	unknown	unknown	gnl\|CDD\|273776
NC_006349.2\|WP_004197883.1\|1076880_1077489_+\|rhomboid-family-intramembrane-serine-protease	unknown	unknown	gnl\|CDD\|223777
NC_006349.2\|WP_004199609.1\|1089930_1090548_+\|GTP-cyclohydrolase-II	unknown	unknown	gnl\|CDD\|234745
NC_006349.2\|WP_004199606.1\|1077613_1079614_-\|ATP-dependent-zinc-metalloprotease-FtsH	unknown	unknown	gnl\|CDD\|273520
NC_006349.2\|WP_004184790.1\|1075225_1076581_+\|amino-acid-permease	unknown	unknown	gnl\|CDD\|163522
NC_006349.2\|WP_004197870.1\|1065802_1069036_-\|CusA/CzcA-family-heavy-metal-efflux-RND-transporter	unknown	unknown	gnl\|CDD\|129992
NC_006349.2\|WP_011204480.1\|1080986_1082753_+\|amidohydrolase-family-protein	unknown	unknown	gnl\|CDD\|226179
NC_006349.2\|WP_004197875.1\|1072182_1072467_-\|hypothetical-protein	unknown	unknown	unknown
NC_006349.2\|WP_004197880.1\|1074472_1074958_+\|YbaK/EbsC-family-protein	unknown	unknown	gnl\|CDD\|239824
NC_006349.2\|WP_004197873.1\|1070561_1071947_-\|TolC-family-protein	unknown	unknown	gnl\|CDD\|224455
NC_006349.2\|WP_004199157.1\|1082883_1083555_-\|transcriptional-regulator	unknown	unknown	gnl\|CDD\|225222
NC_006349.2\|WP_004184766.1\|1063715_1065110_-\|heavy-metal-sensor-histidine-kinase-IrlS	unknown	unknown	gnl\|CDD\|273593

Protein	Function_ID	Function_description	E-value
NC_006349.2\|WP_004197695.1\|1090544_1092242_+\|WD40-repeat-domain-containing-protein	gnl\|CDD\|238121	cd00200, WD40, WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from its N-terminus and the WD dipeptide at its C-terminus and is 40 residues long, hence the name WD40; between GH and WD lies a conserved core; serves as a stable propeller-like platform to which proteins can bind either stably or reversibly; forms a propeller-like structure with several blades where each blade is composed of a four-stranded anti-parallel b-sheet; instances with few detectable copies are hypothesized to form larger structures by dimerization; each WD40 sequence repeat forms the first three strands of one blade and the last strand in the next blade; the last C-terminal WD40 repeat completes the blade structure of the first WD40 repeat to create the closed ring propeller-structure; residues on the top and bottom surface of the propeller are proposed to coordinate interactions with other proteins and/or small ligands; 7 copies of the repeat are present in this alignment.	3.31012e-39
NC_006349.2\|WP_004197872.1\|1069081_1070551_-\|efflux-RND-transporter-periplasmic-adaptor-subunit	gnl\|CDD\|273386	TIGR00999, Nickel-cobalt-cadmium_resistance_protein_NccB, Membrane Fusion Protein cluster 2 (function with RND porters). [Transport and binding proteins, Other].	4.97736e-65
NC_006349.2\|WP_004197868.1\|1065106_1065796_-\|heavy-metal-response-regulator-transcription-factor-IrlR	gnl\|CDD\|130454	TIGR01387, Transcriptional_regulatory_protein_PcoR, heavy metal response regulator. Members of this family contain a response regulator receiver domain (pfam00072) and an associated transcriptional regulatory region (pfam00486). This group is separated phylogenetically from related proteins with similar architecture and contains a number of proteins associated with heavy metal resistance efflux systems for copper, silver, cadmium, and/or zinc. Most members encoded by genes adjacent to genes for encoding a member of the heavy metal sensor histidine kinase family (TIGRFAMs:TIGR01386), its partner in the two-component response regulator system. [Regulatory functions, DNA interactions].	2.40938e-111
NC_006349.2\|WP_004197879.1\|1073657_1074146_-\|adenosine-specific-kinase	gnl\|CDD\|377190	pfam04008, Adenosine_kin, Adenosine specific kinase. The structure of a member of this family from the hyperthermophilic archaeon Pyrobaculum aerophilum contains a modified histidine residue which is interpreted as stable phosphorylation. In vitro binding studies confirmed that adenosine and AMP but not ADP or ATP bind to the protein.	3.29857e-108
NC_006349.2\|WP_004266238.1\|1088035_1089574_+\|efflux-RND-transporter-outer-membrane-subunit-OprB	gnl\|CDD\|182103	PRK09837, PRK09837, Cu(I)/Ag(I) efflux RND transporter outer membrane protein.	5.59568e-111
NC_006349.2\|WP_004199160.1\|1084799_1087901_+\|efflux-RND-transporter-permease-subunit	gnl\|CDD\|169983	PRK09579, PRK09579, multidrug efflux RND transporter permease subunit.	0
NC_006349.2\|WP_004184876.1\|1083705_1084803_+\|efflux-RND-transporter-periplasmic-adaptor-subunit	gnl\|CDD\|273776	TIGR01730, COG0845:_Membrane-fusion_protein, RND family efflux transporter, MFP subunit. This model represents the MFP (membrane fusion protein) component of the RND family of transporters. RND refers to Resistance, Nodulation, and cell Division. It is, in part, a subfamily of pfam00529 (Pfam release 7.5) but hits substantial numbers of proteins missed by that model. The related HlyD secretion protein, for which pfam00529 is named, is outside the scope of this model. Attributed functions imply outward transport. These functions include nodulation, acriflavin resistance, heavy metal efflux, and multidrug resistance proteins. Most members of this family are found in Gram-negative bacteria. The proposed function of MFP proteins is to bring the inner and outer membranes together and enable transport to the outside of the outer membrane. Note, however, that a few members of this family are found in Gram-positive bacteria, where there is no outer membrane. [Transport and binding proteins, Unknown substrate].	9.65507e-71
NC_006349.2\|WP_004197883.1\|1076880_1077489_+\|rhomboid-family-intramembrane-serine-protease	gnl\|CDD\|223777	COG0705, COG0705, Membrane associated serine protease [Amino acid transport and metabolism].	8.96274e-30
NC_006349.2\|WP_004199609.1\|1089930_1090548_+\|GTP-cyclohydrolase-II	gnl\|CDD\|234745	PRK00393, ribA, GTP cyclohydrolase II RibA.	6.64755e-109
NC_006349.2\|WP_004199606.1\|1077613_1079614_-\|ATP-dependent-zinc-metalloprotease-FtsH	gnl\|CDD\|273520	TIGR01241, ATP-dependent_zinc_metalloprotease_FtsH, ATP-dependent metalloprotease FtsH. HflB(FtsH) is a pleiotropic protein required for correct cell division in bacteria. It has ATP-dependent zinc metalloprotease activity. It was formerly designated cell division protein FtsH. [Cellular processes, Cell division, Protein fate, Degradation of proteins, peptides, and glycopeptides].	0
NC_006349.2\|WP_004184790.1\|1075225_1076581_+\|amino-acid-permease	gnl\|CDD\|163522	TIGR03810, arginine-ornithine_antiporter, arginine-ornithine antiporter. Members of this protein family are the arginine/ornithine antiporter, ArcD. This exchanger of ornithine for arginine occurs in a system with arginine deiminase, ornithine carbamoyltransferase, and carbamate kinase, with together turn arginine to ornithine with the generation of ATP and release of CO2. [Transport and binding proteins, Amino acids, peptides and amines].	4.43391e-175
NC_006349.2\|WP_004197870.1\|1065802_1069036_-\|CusA/CzcA-family-heavy-metal-efflux-RND-transporter	gnl\|CDD\|129992	TIGR00914, Nickel-cobalt-cadmium_resistance_protein_NccA, heavy metal efflux pump, CzcA family. This model represents a family of H+/heavy metal cation antiporters. This family is one of several subfamilies within the scope of pfam00873. [Cellular processes, Detoxification, Transport and binding proteins, Cations and iron carrying compounds].	0
NC_006349.2\|WP_011204480.1\|1080986_1082753_+\|amidohydrolase-family-protein	gnl\|CDD\|226179	COG3653, COG3653, N-acyl-D-aspartate/D-glutamate deacylase [Secondary metabolites biosynthesis, transport, and catabolism].	7.21127e-151
NC_006349.2\|WP_004197880.1\|1074472_1074958_+\|YbaK/EbsC-family-protein	gnl\|CDD\|239824	cd04332, YbaK_like, YbaK-like. The YbaK family of deacylase domains includes the INS amino acid-editing domain of the bacterial class II prolyl tRNA synthetase (ProRS), and it's trans-acting homologs, YbaK, ProX, and PrdX. The primary function of INS is to hydrolyze mischarged cysteinyl-tRNA(Pro)'s, thus helping ensure the fidelity of translation. Organisms whose ProRS lacks the INS domain express an INS homolog in trans (e.g. YbaK, ProX, or PrdX).	4.00352e-32
NC_006349.2\|WP_004197873.1\|1070561_1071947_-\|TolC-family-protein	gnl\|CDD\|224455	COG1538, TolC, Outer membrane protein [Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion].	1.82633e-32
NC_006349.2\|WP_004199157.1\|1082883_1083555_-\|transcriptional-regulator	gnl\|CDD\|225222	COG2345, COG2345, Predicted transcriptional regulator [Transcription].	5.95232e-60
NC_006349.2\|WP_004184766.1\|1063715_1065110_-\|heavy-metal-sensor-histidine-kinase-IrlS	gnl\|CDD\|273593	TIGR01386, Probable_sensor_protein_PcoS, heavy metal sensor kinase. Members of this family contain a sensor histidine kinase domain (pfam00512) and a domain found in bacterial signal proteins (pfam00672). This group is separated phylogenetically from related proteins with similar architecture and contains a number of proteins associated with heavy metal resistance efflux systems for copper, silver, cadmium, and/or zinc.	0

>NC_006349.2|WP_004184790.1|1075225_1076581_+|amino-acid-permease
MKHSVRHPFHPSTPLPASASAPLRAAAPRQLPFALLTALVIGSMIGSGIFSLPQNMASGAGAGAIVIGWAITGVGMLMLALVYQTLAHRKPELDNGVYAYAHASAGDFVGFNSAWGYWVSAWIGNVGYLVIVFGTLGYAFPAFGDGNTRAALAFQPHRFTTDFWGNVHLPGVLDQVKSTMLITVWVFIGIEGASVYSARAKNRDDVGRATIVGFVVVLLLLMAVSLLSLGIVSQPELAAMKNPSMAGVLEKAIGRTGVAIAGVGLLVSVGGALLAWTLLAAEAMFTPAKDGVMPAFLSRENAHGVPANALWATNGLVQLFLLVTLVSNATYQALISLATSMILVPYLFSAVYALVIAIKGEGYAPGEAVRVRDATIGAVATVYCGWLLYAAGPKYLLLSALLYAPGALLYAWAKRERGERPFKPFEAAILIALVAFASLAGWLVAAGRISL
>NC_006349.2|WP_004197880.1|1074472_1074958_+|YbaK/EbsC-family-protein
MSMSVTLQECLRQKASRYEVIHHPYSHSNMEAAAAAHVPGDRLAKTVLLEDAQGYVAAVLPTTHAVRLSELWAKTGRHLVLAKEVELRELFKDCDVGALPPVCMAYGMQTFLDDSLARQPDVYFEAGDHEELVHMDRDEFLALMDKAERASFSHKIQGVVS
>NC_006349.2|WP_004197879.1|1073657_1074146_-|adenosine-specific-kinase
MLQLLSVAIDKPDTANFILGQTHFIKSVEDIHEALVGAVPGIRFGLAFCEASGKRLVRHSGTGAALTELACRNALAIGAGHCFLVFLGDGFYPLNVLNAIKAVPEVCRIFCATANPTEVVVAQSDQGRSILGVVDGFSPLGIETDEDVRWRKDLLRNIGYKA
>NC_006349.2|WP_004524134.1|1072864_1073005_-|bacteriophage-protein
MSLAAQDLIELLRLAQGGAGALTLHLLREIAGNLIAFGVADCRGGC
>NC_006349.2|WP_004197875.1|1072182_1072467_-|hypothetical-protein
MKRATSLAFAALFALAASSAFAHGMPERVFKERKPIRADARQEPSQRDASSAGCASGCPAGAALSRQDDRASGASPSSVGVEAAAGVHPAVNGG
>NC_006349.2|WP_004197873.1|1070561_1071947_-|TolC-family-protein
MPKRIFAALVSAAIAASAVQAQAQPAPAPSAPDGPAAAPPDARAASVSVTPAVSPAPISTSTVSVAPPALSLDDALALAAANNPLLKSARSSADASVGALVQAGARPNPTVSFLQEGFGRQERTTTAVVSQPIELGGKRRSRVDAASYGRESALASLDGRAAALRADVTGAFYGVLAAQRQLQVADESAAIAARSADMADKRARAGKVSPVEATKARVAQTAAQIELSNAQTRVAAALARLANATGSADVRGRAASGDLDALPAAEPLPQLLGRLDDAPLARAAKADMLRTNAQIAIERAKRVPDITVSAGVKHVVTGGAPDNQAVVGISIPLPLFDTNRGALLEAVHNAAKASADFDAERARLRLDLTQAYANYERATGEARRLKADVLPAARQSLDAMSRGYQLGKFGFLDVLDAQRTLFDAQSRYVQALADAHQSYADIERVVGAPARDASRPLAQLR
>NC_006349.2|WP_004197872.1|1069081_1070551_-|efflux-RND-transporter-periplasmic-adaptor-subunit
MQRKPLILAGAAAAGALAIVLALARAPSTSSAPAASGAAAAAPASGATGPHGGAMFAQGALSAEIVLSEKPDDARLVVYPFVDGKPVEQGAAVSATLTRHDGERVALQFAQAGAKYTSAQPIARPHVFDASIDVRIGARSASFPFSRADGAIALDDAQLGAARIGIARAGPAQIITSFQLPGEIKFNEDRTAHVVPRVAGIVERVAVSIGENVKPGQVLAVIASTDLADRRSELMTAERRLQAARTSYAREKTLWEERISAEQDYLQAQVQLREAEIAAANARQKLAALNASAASGALNRYELRAPFAGTIVEKHIAPGEAIAADANVFVVSDLSSVWAEMAVPAQRLNDVRVGRHATVSAAAFESKSSGPIAYVGALLGEQTRTAPARVVLPNPDGAWRPGMFVNVTVDAGAQNVPVAVESDALQDVDGAPAVFVRTPKGFVAQAIETGRRDERRVEIVKGLAPGQTYAAANSFVLKAELGKGVADEH
>NC_006349.2|WP_004197870.1|1065802_1069036_-|CusA/CzcA-family-heavy-metal-efflux-RND-transporter
MFERLIRFAIAHRWLVMLAIVAAASLGVYSYQKLPIDAVPDITNVQVQVNTSAPGYSPLEAEQRITYPVETAMAGLPNLEQTRSISRYGLSQVTVIFKDGTDIYFARQLVNERIQEAKDKLPPGIAPAMGPTSTGLGEIYLWTVEADAGARKPDGTRYTSADLRELQDWVVRPQLRNVPGVTEVNSIGGYVKEYRVAPNPTKLMSYGLTLADVVRALERNNDNVGAGYIEKRGEQYLVRVPGQARSAEDIANIVLVNAGGVPVRMKDIGAVDLGRELRTGAATANGEEVVLGTVFMLMGENSRTVAKAVAARMADVNRTLPAGVRAIAVYDRTVLVEKAVRTVKKNLLEGAVLVIAVLFLFLGNIRAAVITALVIPLSMLMTFTGMVNAKVSANLMSLGALDFGIIVDGAVVIVENCIRRLAHAQQAAGRPLTRDERFAEVFAASQEARRALIFGQLIIMVVYLPIFALTGVEGKMFHPMAITVVMALAAAMALTVTFIPAAVALFIGRRVEEKENRLMSAAKRLYAPVLDAFVARPGQVLAGATAVVALSLVLATRLGSEFIPSLNEGDLAVSAQRIPGTSLTQSVAMQQSIEKTLKARFPEIDRVFARTGTAEIAADPMPPNLSDGYIMLKPADQWPDPRKSRDALRGEIEAVLAQLPGNAYEFSQPIQLRFNELISGVRSDVAVKIFGDDMATLNATGEQIAAALQKVPGASEVKVEQTTGLPVLTVNLDRDKLARYGVTVGDVQDTVAAAVGGRKAGLLFQGDRRFDIVVRLPDELRTDVEAIKRLPIALPLAAPAGASGPLAQAPYVPLAELATVDTSPGPNQISREDGKRRVVVSANVRGRDVGSFVADARERIASDVRVPAGYWLSWGGQFEQLQSASERLKIVVPLALAMVFVLLFVMFNNAKDGLLVFTGIPFALTGDVVSLWLRGIPLSITAAVGFIALSGVAVLNSLVMISFIRNLRDEGAPLDAAVREGALTRLRPVLMTALVASLGFLPMAFATGTGAEVQRPLATVVIGGILSSTALTLLVLPVLYRVAHAAPPRATLGARAAGWLARLAPAAVLRRRRESSR
>NC_006349.2|WP_004197868.1|1065106_1065796_-|heavy-metal-response-regulator-transcription-factor-IrlR
MRILIVEDEPKTGMYLRKGLTEAGFIADWVEDGVTGLHQAETEEYDLIILDVMLPGHDGWTVLERLRRAHSTPVLFLTARDDVGDRVKGLELGADDYVVKPFDFVELVARVRSILRRGQARESTVLRIADLELDLTRRKATRQGDVVLLTAKEFALLWLLMRREGEILPRATIASQVWDMNFNSDTNVVDAAIRRLRSKIDDAYEPKLIHTVRGMGYVLEVRSASAPSR
>NC_006349.2|WP_004184766.1|1063715_1065110_-|heavy-metal-sensor-histidine-kinase-IrlS
MIRRLLPRTLRARLTALIILSTAATLALSGVALYSALHNRLVGMSSYEMSATLAAMRTHLANVANVDDIPRKSDLWIDQLHGHQNLDLAIYDTDGRLRFATRGFVAPRPALGAPQTRVPASAAPAGATFSYLADDAPLRGGNPRTARIVVQYDGKNDHALLRAYAYTVVVIEVLAVVLTAALAYGIAMLGLSPLRRLVARAEQMSSSRLAQPLPELDTSGELKEMEHAFNAMLKRLDESFVRLSQFSSNLAHDMRTPLTNLLAEAQVALSKPRTADEYRDVIESSIDEYQRLSRMIEDMLFLARSDNAQSHLAIRTLDAAAQAERVAGYYEPMAEDAEVSIVVRGKAEVRADALLYHRALSNLISNALNHAPRGSTITIECAQAADAATISVSDTGRGIEAPHRERIFERFYRVDPARHNSASGTGLGLAIVRSIMENHGGTCGVDSEPHVRTTFWLKFPAHAA
>NC_006349.2|WP_004197883.1|1076880_1077489_+|rhomboid-family-intramembrane-serine-protease
MTLAIVVLNVIGFLVELAAPERVLSLFALWPPRAGAGLPPAAAPAFHVWQLVTYSALHAGLSHLLFNMLGLVMFGRDVERALGRARFGTLYLASVVCGALTQLALARYSAAAAAPTIGASAGVFGVLAAYALLYPSRRVVLLIPPIPMRAWVFALLYAGGELLLGVAGAASGIAHFAHLGGMFGAIALMLAWGRPRSEWPVQ
>NC_006349.2|WP_004199606.1|1077613_1079614_-|ATP-dependent-zinc-metalloprotease-FtsH
MKSETGYMGFVVVLVFMVLLALQLATLSAPATQIAYSDFRKLAAAAQLDDLEVSPTRITGVLRSASAAAALPASDAEAIKRAGTPWRFSTKRVTDERLIDTLAATGTRYRGADDDTWIGTLASWIVPIAVFALVWNLMLRRPRGGLQDWSGVGKSKPRVYVEAKTGIDFDDIAGIDEAKAELQQIVAFLRAPARYQRLGGKIPKGVLIVGAPGTGKTLLAKAVAGEAGVPFFSTSGSSFVEMFVGVGAARVRDLFEQAQQKAPCIIFIDELDALGKVRGAGLASGNDEREQTLNQLLVEMDGFQANSGVILMAATNRPEILDPALLRPGRFDRHIAIDRPDLTGRRQILSVHVKHVKLGPDVDLGELASHTPGFVGADLANIVNEAALHAAELDKPAIDMSDFDEAIDRAMTGMERKSRVMSEREKITIAHHEAGHALIAQTRAHSDPVKKVSIIPRGIAALGYTQQVPTEDRYVLRKSELLDRLDVLLGGRVAEEIVFGDVSTGAENDLERATEMARHMVARYGMSERIGLATFGDADTQGLSPLVWQRGGERCSESTATRIDDEIQRLLAEAHDRVSRTLKERRGALERIAGYLLEHEVVDHDKLVRLVNDEPTPEPGARDPGGDAAKRSGIGAAPAKPPAEVGSAELRDPARKADNADHSVPQ
>NC_006349.2|WP_011204480.1|1080986_1082753_+|amidohydrolase-family-protein
MTRYDTIIRNGLWFDGTLAEPRPRELGIRDGRVAAVSDTPLAADGASVIDATGKWVMPGFIDIHTHYDAEILVSPGLPESVRHGVTSVFLGSCSLSTVHANALDCTDLFSRVEALPREQMLAVLSRVKTWDTAAAYVRHLESLPLGPNVAAFLGHSDLRTHVLGLGRAVDDRVRPHEAELQRMERLLDDALDAGFVGLSSMTTPWDKLDGERYRSKSLPSTFATWREYRRLNRVLRRRGRVLQSAPNTTNPLNGLLFMAESCGYFVRKPLRTSLLVAADSKAAPRGTIDVQLGGVRVANALFRGELVWQHLPVPFEVYADGIDFVIFEEFGAGRAALHLADALERNKLLQNEGYRREFRRQVGKGFDLRLWTRDLHDTRIVGCPDASVVGKSFGQVANERGVHPADAFLDLVVAHGQRLRWCMTIANHRADVLDRIATHPALQIGFADSGAHLRNMAFYNAPVRFLRRVREAERAGRPFMSVQQAVHRLTGELGAYFGVDAGTLRAGDRADIAIVDPAHLDASVDASVDAYHEEDMAVFGGLRRLVNRSGAAIAATLVNGQLVYRDGAFAEGFGDTRRSGRFLRAAAR
>NC_006349.2|WP_004199157.1|1082883_1083555_-|transcriptional-regulator
MDDNFSKQEIPVSERVLNVLKRRGPLQAAELGAYLGTTGEAARQQLKKLEAEGLVEAQNVPQGVGRPARIWRLTSLGHGHFPDAHADMTVDLIRIIRTTLGQPTLDLLIAARETEMRRTYAHTLAGVTDPEERIARLAELRDREGYFAEWSRAPDGDGWLFIENHCPICAAATACQGFCRSELEIFREMLGDALTIERIEHIPAGARRCAYRIRPSGAGAGGE
>NC_006349.2|WP_004184876.1|1083705_1084803_+|efflux-RND-transporter-periplasmic-adaptor-subunit
MGRRLLLALALLAFIFGGLFLWRESRVQAADHPPAPPAALTVSAVAVRAAPERVTLDAVGSLDAVRQVTLAPEVAGRVVALQFDAGSAVRKGQLIVQLFDEPERAKLASIQAKAAYAKRQLDRSQALAQTGAEPRNLFDRHRFDFDAAAADIRETQAVITQKAVRAPFDGVLGLRRVNLGQYLNAGDAIATLTDLDTLYANFTVPQKNLSQLRLGQSVSITTDAYPERTLVARVSAIEPQIGTDTRNVAVQATLPNPDHLLRPGMYIQARLELPPRERALTVPDTAVQTSQRGESVLVVGKPGRDGLGVVRLQPVRTGRRADGRIAIADGLRPGDVVVTSGQVRLAAGDRVKVALDDGAGSGAAQ
>NC_006349.2|WP_004199160.1|1084799_1087901_+|efflux-RND-transporter-permease-subunit
MNAGAPHDSGAARARFTDVFVRRPVLSLVFSLLILLVGLRALMSLPVRQYPALESATISVATDYPGASQELMQGFVTTPIAQSIATADGIEYITSTTTQGKSVVKARLRLNANADRAMTEVMAKVQQVKYKLPADAYDSVITKLTDAPTAVMYLGFASDALSIAQITDYVVRVAQPLVTTVPGVASAEILGGQNLAMRVWLDATRLAAHGLSAGDVAAAIRANNVQAAPGQVKGSLTIADISANTDLTDVGAFNEMVVKSAPNGGGLVRLKDVATVEIGGENYNSSALMNGRRAVYIAVNATPAGNPLEIVRGVGAVLPAIERNKPASVQIANMFDGARFVNASIAEVRSTLTEAIAIVVVVIFLFLGSFRAVIIPVLTIPLSLVGSAALMLAAGFSLNLLTLLAMVLAIGLVVDDAIVVVENIHRHIEQGEPPVRAALIGAREIASPVLVMMATLISVYAPIGLMGGLTGLLFKEFAFTLAGAVLVSGIVALTLSPMLGSLLLTSRMSEGRVAKAIERTLERVTHAYRRGLHASLAARPAILLIGAGVLAGIVLLFSGVKRELAPQEDQGSIMVAVKAPQYANLDYMERYAPDIERVFRTLPEADTSFILNSYGGSNLGFAGVNLVDWDKRTRSAAALQALIQARGDGIRGERVFAFQLPALPASSGGLPIQMVLRTPSGFADLYAQMERIKAAAQKSGLFAVLDSDLTFDSRAVGVTIDRNQANTLGVTMKDIADTLAVLVGENYVNRFNFKGRSYDVIPQVSRSERLSSEMLSRYYVKTGSGRMIPLSTVIQVTNGSQANALSQFNQMNAATFSAVPAPGVTMGDAVAFLEAQKLPAGFSIDWLGESRQYVQEGNRLAVTFGFALIVIFLVLAAQFESLRDPLVILVSVPLSICGALAPLYLGFATLNIYTQIGLVTLIGLISKHGILMVSFANDLQRHEGLDRRAAIERAAAVRLRPILMTTAAMVAGLVPLVFAAGAGAASRFAIGITVSTGMLVGTLFVLPTVYTFVAKDHGAAMRSERAQLLAATR
>NC_006349.2|WP_004266238.1|1088035_1089574_+|efflux-RND-transporter-outer-membrane-subunit-OprB
MRTAVRAAAVAAAFFAAGCTLAPRYERPAAPVSGAFPADGVYAAQPGAAPGARSANGQAAVDIGWREFFVDPRLQRLIEIALKNNRDLRVSVLNVEASRAQYQITRAGLFPTLSGTGTGTIQRTPAGVSITGQPLISRTYNVGVSASWELDLFGRVQSLKDQALAQYFATAQARKAAEISLVASVADQYLTLLSTDDLLQVTQNTLKSARASYDLTKLQFDNGTGSELDLRQAQTVVETALASQQAQARARAQALNALVLLIGEPLPDDLPADLPLNAQNLLTDIPAGLPSDLLTRRPDIMQAEETLRAANANIGAARAAFFPKISLTSAFGTASTTLGGLFKAGTAAWSFAPNIALPIFEGGQNIANLDLAHVQKRIEIANYEKAIQSAFREVSDGLAARGTYDQQIAALERNEHAQQRRYDLSDLRYRNGVDSYLSVLTAQTDLYSAQQQLISARLARWTNLVDLYRALGGGWLERAGETPRPADAPVDYGKAAPAPAASASARTAAVIG
>NC_006349.2|WP_004184915.1|1089588_1089885_+|hypothetical-protein
MRQPNARQHSARRPSAARAGRERIGRTWRTKKKTDREMIGDTVIGTDAQSAMLLHNRTQQPIKSSPRTRETATNRKSIQAFDITIQKLPCSSQCVSQC
>NC_006349.2|WP_004199609.1|1089930_1090548_+|GTP-cyclohydrolase-II
MSASVRTRVNVPIRPRTAQQRFDAEMVTFQGLCDSAEHLALVFGPLADAPLVRVHSECLTGDVFGSARCDCGEQLDESVAMFGREGGILLYLRQEGRGIGLYNKLDAYRLQISQGLDTFAANRALNFPDDLRDFRVAAQMLQALGVTEISLVTNNPDKVSQIEKHGIRIRRVLQTGVFVNTTNHGYLRAKIDHHRHAINLSQELQ
>NC_006349.2|WP_004197695.1|1090544_1092242_+|WD40-repeat-domain-containing-protein
MITHRAPISGIAAHRDQYVLTAGYDNQVILWDAKTQRPLARAMHDHLANQGAFSPDGAYVVTSSSDYSARLWTVPDLRLVAVFADQEDDVEMSVFHPDKPLVATASRDHRVRVYDFGGKLLHTFSGHTADVISVEWMRGADEIVSSSDDGTIKRWSLANNGLVADIDLDGIETDTIAIAADGRIFAGNDEGEIISIGVDGARATIAAHDAGVKRLVLDGERGLLVSLSYDRTMRLWKVGAAGEPRALGGAALPPEVWPRSCSFEGDEHIVFSTFHSSYRRYNWKTERWDAAELPPTHGVNAVQPVDGHLWTIGDAGIVRVDQREHARTGSLCNFLAPAGELILTGGQLGKVFDARSGRELHQHRSPLNCGVAFARDGAAHAVIGTYTGEGIVLRIDGTRATHVADLPLHANAVKGIAISGDLIFSVAADASATWYRASTLEPAFELKRAHDKIANGCAGLGDGYFASVSRDLKLRIWSPDSHAEVIATPHTHSIKCVAASADGRYVATGSYNGRVAVYDRVETRWALDARVTTAGVSSLAYDPAARAFLASSYDGNVYRIPLERA

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Crispr_ID: NC_006349_3

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_006349_3

2214654-2214799

Orphan

Consensus_repeat	Method
GCAGAGGCGCCGCCGCCGGAATACCCGATCATCGGGATGCTCGATCGCCGAAG	PILER-CR
CGGAATGCCCGATCATCGGGATGC	CRISPRCasFinder

2 spacers

The CRISPR arrays of NC_006349_3

>merge|NC_006349|3|2214654-2214799|PILER-CR,CRISPRCasFinder
TCGTCGGGATGCTCGATTGCCGCAGTCACCCTCCGCCGGGGCTCCGTCGTCGGAATGCCCGATCATCGGGATGCCTGCTCGCCGAAGCACTCCACCGCAGAGGCGCCGCCGCCGGAATACCCGATCATCGGGATGCTCGATCGCCG

>NC_006349|3|2|2214654-2214799|PILER-CR
TCGTCGGGATGCTCGATTGCCGCAGTCACCCTCCGCCGGGGCTCCGTCGTCGGAA	TGCCCGAT
CATCGGGATGCCTGCTCGCCGAAGCACTCCACCGCAGAGGCGCCGCCGCCGGAAT	ACCCGATCA
TCGGGATGCTCGATCGCCG

>NC_006349|3|2|2214704-2214789|CRISPRCasFinder
CGGAATGCCCGATCATCGGGATGC	CTGCTCGCCGAAGCACTCCACCGCAGAGGCGCCGCCGC
CGGAATACCCGATCATCGGGATGC

Protein	Signature genes	Signature genes Name	Protein_function
NC_006349.2\|WP_004187710.1\|2218786_2220589_+\|bifunctional-aminoglycoside-phosphotransferase/ATP-binding-protein	unknown	unknown	gnl\|CDD\|225098
NC_006349.2\|WP_004188488.1\|2208722_2208920_+\|hypothetical-protein	unknown	unknown	unknown
NC_006349.2\|WP_004200700.1\|2205958_2207074_-\|SRPBCC-family-protein	unknown	unknown	gnl\|CDD\|378454
NC_006349.2\|WP_004187057.1\|2200196_2201648_-\|2-oxo-acid-dehydrogenase-subunit-E2	unknown	unknown	gnl\|CDD\|237001
NC_006349.2\|WP_011204700.1\|2224009_2224384_+\|hypothetical-protein	unknown	unknown	unknown
NC_006349.2\|WP_011204701.1\|2225980_2226415_-\|Hsp20/alpha-crystallin-family-protein	unknown	unknown	gnl\|CDD\|223149
NC_006349.2\|WP_004187792.1\|2222144_2223977_+\|STAS-domain-containing-protein	unknown	unknown	gnl\|CDD\|223732
NC_006349.2\|WP_004187216.1\|2211188_2213462_-\|FAD-dependent-oxidoreductase	unknown	unknown	gnl\|CDD\|369639
NC_006349.2\|WP_004529492.1\|2216870_2218712_+\|ribonucleotide-reductase-like-protein	unknown	unknown	gnl\|CDD\|180772
NC_006349.2\|WP_004200699.1\|2202698_2203931_-\|3-methyl-2-oxobutanoate-dehydrogenase-(2-methylpropanoyl-transferring)-subunit-alpha	unknown	unknown	gnl\|CDD\|223997
NC_006349.2\|WP_004188034.1\|2215356_2216622_+\|polyhydroxyalkanoate-depolymerase	unknown	unknown	gnl\|CDD\|130908
NC_006349.2\|WP_004188830.1\|2208979_2210878_+\|GMC-family-oxidoreductase	unknown	unknown	gnl\|CDD\|225186
NC_006349.2\|WP_004200705.1\|2225259_2225913_+\|SagB/ThcOx-family-dehydrogenase	unknown	unknown	gnl\|CDD\|380318
NC_006349.2\|WP_004205322.1\|2207371_2208307_+\|LysR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|176109
NC_006349.2\|WP_004187469.1\|2213594_2213990_-\|TraR/DksA-C4-type-zinc-finger-protein	unknown	unknown	gnl\|CDD\|224648
NC_006349.2\|WP_004188244.1\|2226820_2227951_-\|porin	unknown	unknown	gnl\|CDD\|238208
NC_006349.2\|WP_004187137.1\|2224356_2224806_-\|CBS-domain-containing-protein	unknown	unknown	gnl\|CDD\|341411
NC_006349.2\|WP_004188282.1\|2201649_2202693_-\|alpha-ketoacid-dehydrogenase-subunit-beta	unknown	unknown	gnl\|CDD\|223101
NC_006349.2\|WP_162473582.1\|2220722_2221019_+\|quinone-oxidoreductase	unknown	unknown	unknown
NC_006349.2\|WP_004196898.1\|2205183_2205624_+\|SRPBCC-family-protein	unknown	unknown	gnl\|CDD\|176863

Protein	Function_ID	Function_description	E-value
NC_006349.2\|WP_004187710.1\|2218786_2220589_+\|bifunctional-aminoglycoside-phosphotransferase/ATP-binding-protein	gnl\|CDD\|225098	COG2187, COG2187, Uncharacterized protein conserved in bacteria [Function unknown].	9.00049e-75
NC_006349.2\|WP_004200699.1\|2202698_2203931_-\|3-methyl-2-oxobutanoate-dehydrogenase-(2-methylpropanoyl-transferring)-subunit-alpha	gnl\|CDD\|223997	COG1071, AcoA, Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit [Energy production and conversion].	8.93075e-143
NC_006349.2\|WP_004200700.1\|2205958_2207074_-\|SRPBCC-family-protein	gnl\|CDD\|378454	pfam10604, Polyketide_cyc2, Polyketide cyclase / dehydrase and lipid transport. This family contains polyketide cylcases/dehydrases which are enzymes involved in polyketide synthesis. It also includes other proteins of the START superfamily.	2.16274e-11
NC_006349.2\|WP_004187057.1\|2200196_2201648_-\|2-oxo-acid-dehydrogenase-subunit-E2	gnl\|CDD\|237001	PRK11856, PRK11856, branched-chain alpha-keto acid dehydrogenase subunit E2; Reviewed.	1.49267e-132
NC_006349.2\|WP_004187137.1\|2224356_2224806_-\|CBS-domain-containing-protein	gnl\|CDD\|341411	cd17775, CBS_pair_bact_arch, Two tandem repeats of the cystathionine beta-synthase (CBS pair) domains present in bacteria and archaea. The CBS domain, named after human CBS, is a small domain originally identified in cystathionine beta-synthase and is subsequently found in a wide range of different proteins. CBS domains usually occur in tandem repeats. They associate to form a so-called Bateman domain or a CBS pair based on crystallographic studies in bacteria. The CBS pair was used as a basis for this cd hierarchy since the human CBS proteins can adopt the typical core structure and form an intramolecular CBS pair. The interface between the two CBS domains forms a cleft that is a potential ligand binding site. The CBS pair coexists with a variety of other functional domains and this has been used to help in its classification here. It has been proposed that the CBS domain may play a regulatory role, although its exact function is unknown. Mutations of conserved residues within this domain are associated with a variety of human hereditary diseases, including congenital myotonia, idiopathic generalized epilepsy, hypercalciuric nephrolithiasis, and classic Bartter syndrome (CLC chloride channel family members), Wolff-Parkinson-White syndrome (gamma 2 subunit of AMP-activated protein kinase), retinitis pigmentosa (IMP dehydrogenase-1), and homocystinuria (cystathionine beta-synthase).	1.39507e-50
NC_006349.2\|WP_011204701.1\|2225980_2226415_-\|Hsp20/alpha-crystallin-family-protein	gnl\|CDD\|223149	COG0071, IbpA, Molecular chaperone (small heat shock protein) [Posttranslational modification, protein turnover, chaperones].	2.04683e-32
NC_006349.2\|WP_004187792.1\|2222144_2223977_+\|STAS-domain-containing-protein	gnl\|CDD\|223732	COG0659, SUL1, Sulfate permease and related transporters (MFS superfamily) [Inorganic ion transport and metabolism].	2.60835e-107
NC_006349.2\|WP_004187216.1\|2211188_2213462_-\|FAD-dependent-oxidoreductase	gnl\|CDD\|369639	pfam07992, Pyr_redox_2, Pyridine nucleotide-disulphide oxidoreductase. This family includes both class I and class II oxidoreductases and also NADH oxidases and peroxidases. This domain is actually a small NADH binding domain within a larger FAD binding domain.	7.15563e-57
NC_006349.2\|WP_004529492.1\|2216870_2218712_+\|ribonucleotide-reductase-like-protein	gnl\|CDD\|180772	PRK06948, PRK06948, ribonucleotide reductase-like protein; Provisional.	0
NC_006349.2\|WP_004188034.1\|2215356_2216622_+\|polyhydroxyalkanoate-depolymerase	gnl\|CDD\|130908	TIGR01849, unnamed_protein_product, polyhydroxyalkanoate depolymerase, intracellular. This model represents an intracellular depolymerase for polyhydroxyalkanoate (PHA), a carbon and energy storing polyester that accumulates in granules in many bacterial species when carbon sources are abundant but other nutrients are limiting. This family is named for PHAs generally, rather than polyhydroxybutyrate (PHB) specificially as in Ralstonia eutropha H16, to avoid overcalling chemical specificity in other species. Note that this family lacks the classic GXSXG lipase motif and instead shows weak similarity to some [Fatty acid and phospholipid metabolism, Degradation].	1.36366e-112
NC_006349.2\|WP_004188830.1\|2208979_2210878_+\|GMC-family-oxidoreductase	gnl\|CDD\|225186	COG2303, BetA, Choline dehydrogenase and related flavoproteins [Amino acid transport and metabolism].	1.06055e-34
NC_006349.2\|WP_004200705.1\|2225259_2225913_+\|SagB/ThcOx-family-dehydrogenase	gnl\|CDD\|380318	cd02142, McbC_SagB-like_oxidoreductase, oxidase similar to the microcin B17 processing protein McbC. This family is the oxidase domain of NRPS (non-ribosomal peptide synthetase) and other systems that modify polypeptides by cyclizing a thioester to form a ring. These include EpoB, part of the epothilone biosynthesis pathway; TubD, part of the tubulysin biosynthesis pathway, MtsD, part of the myxothiozol biosynthesis pathway; IndC, part of the indigoidine biosynthesis pathway and TfxB, part of the trifitoxin processing pathway. All are FMN-dependent and oxidize the product of the cyclization of thioesters in short polypeptides.	6.31252e-20
NC_006349.2\|WP_004205322.1\|2207371_2208307_+\|LysR-family-transcriptional-regulator	gnl\|CDD\|176109	cd08417, PBP2_Nitroaromatics_like, The C-terminal substrate binding domain of LysR-type transcriptional regulators that involved in the catabolism of nitroaromatic/naphthalene compounds and that of related regulators; contains the type 2 periplasmic binding fold. This CD includes the C-terminal substrate binding domain of LysR-type transcriptional regulators involved in the catabolism of dinitrotoluene and similar compounds, such as DntR, NahR, and LinR. The transcription of the genes encoding enzymes involved in such degradation is regulated and expression of these enzymes is enhanced by inducers, which are either an intermediate in the metabolic pathway or compounds to be degraded. Also included are related LysR-type regulators clustered together in phylogenetic trees, including NodD, ToxR, LeuO, SyrM, TdcA, and PnbR. This substrate-binding domain shows significant homology to the type 2 periplasmic binding proteins (PBP2), which are responsible for the uptake of a variety of substrates such as phosphate, sulfate, polysaccharides, lysine/arginine/ornithine, and histidine. The PBP2 bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap. After binding their specific ligand with high affinity, they can interact with a cognate membrane transport complex comprised of two integral membrane domains and two cytoplasmically located ATPase domains. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis.	7.67997e-62
NC_006349.2\|WP_004187469.1\|2213594_2213990_-\|TraR/DksA-C4-type-zinc-finger-protein	gnl\|CDD\|224648	COG1734, DksA, DnaK suppressor protein [Signal transduction mechanisms].	1.7869e-14
NC_006349.2\|WP_004188244.1\|2226820_2227951_-\|porin	gnl\|CDD\|238208	cd00342, gram_neg_porins, Porins form aqueous channels for the diffusion of small hydrophillic molecules across the outer membrane. Individual 16-strand anti-parallel beta-barrels form a central pore, and trimerizes thru mainly hydrophobic interactions at the interface. Trimers are stabilized by hytrophillic clamping of Loop L2. Loop 3 bends into the pore, creating an elliptical constriction of about 7 x 11A, large enough to allow passage of a glucose molecule without steric hindrance. Removal of the C-terminal residue (usuallly F) destabilizes the trimer and removal of the 16th beta-sheet abolishes trimerization. Unlike typical membrane proteins, porins lack long hydrophobic stretches. Short turns are found at the smooth, periplasmic end, longer irregular loops are found at the rough, extracellular end. C-terminal residue forms salt bridge with N-terminus.	2.53339e-55
NC_006349.2\|WP_004188282.1\|2201649_2202693_-\|alpha-ketoacid-dehydrogenase-subunit-beta	gnl\|CDD\|223101	COG0022, AcoB, Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit [Energy production and conversion].	0
NC_006349.2\|WP_004196898.1\|2205183_2205624_+\|SRPBCC-family-protein	gnl\|CDD\|176863	cd07821, PYR_PYL_RCAR_like, Pyrabactin resistance 1 (PYR1), PYR1-like (PYL), regulatory component of abscisic acid receptors (RCARs), and related proteins. The PYR/PYL/RCAR-like family belongs to the SRPBCC (START/RHO_alpha_C/PITP/Bet_v1/CoxG/CalC) domain superfamily of proteins that bind hydrophobic ligands. SRPBCC domains have a deep hydrophobic ligand-binding pocket. PYR/PYL/RCAR plant proteins are receptors involved in signal transduction. They bind abscisic acid (ABA) and mediate its signaling. ABA is a vital plant hormone, which regulates plant growth, development, and response to environmental stresses. Upon binding ABA, these plant proteins interact with a type 2C protein phosphatase (PP2C), such as ABI1 and ABI2, and inhibit their activity. When ABA is bound, a loop (designated the gate/CL2 loop) closes over the ligand binding pocket, resulting in the weakening of the inactive PYL dimer and facilitating type 2C protein phosphatase binding. In the ABA:PYL1:ABI1 complex, the gate blocks substrate access to the phosphatase active site. A conserved Trp from PP2C inserts into PYL to lock the receptor in a closed formation. This group also contains Methylobacterium extorquens AM1 MxaD. The mxaD gene is located within the mxaFJGIR(S)ACKLDEHB cluster which encodes proteins involved in methanol oxidation. MxaD may participate in the periplasmic electron transport chain for oxidation of methanol. Mutants lacking MxaD exhibit a reduced growth on methanol, and a lower rate of respiration with methanol.	3.1145e-25

>NC_006349.2|WP_004187469.1|2213594_2213990_-|TraR/DksA-C4-type-zinc-finger-protein
MAAFDEHQLQVLGALLRACRQALQADVRAGERQRADEPYANLAGPAPDEGDEANADLFVDVDHALLGMKLAELRDVDAALQRIARRDYGCCADCGQPIAYERLLARPTALRCAPCQRAHERRFATQPRPSL
>NC_006349.2|WP_004187216.1|2211188_2213462_-|FAD-dependent-oxidoreductase
MREFDYLLVGGGIASVTAARTLRGEDASASIAILCGEPVLPYQRPPLSQEWLMGAVQPASITLHDAAFYAAQRIDIALGVRAEQLDRAKRIVRTSSGATFRYGKLLIATGASAKAPALPGFGLDGVHVLHTFAQAQALKDAAAHARRATVLGGGFLGVEIAATLQALGLQVTLVERAPGVMPSLRAPALGGHFEALCRARGIDVLTRCEVRRVLGAQCVEAVETSDGGTRPCDLFVAAVGVTPNCGWLDGSGLALGDGVEVDAFLQTADPDVFAAGDVAHFDDPIFGVRRRIEHWDNAVRQGRIAARNMLGHRLPYRDVSIFYGSVFGLSYNLLGYPVGATETIERGAFDEASYMQLYLADDVLRAAFTIDRPAVEIAALNDAIRLHVNVAAHKMKLSDPNYPLDKLPVQTILILQGGGALGAFECGAVKALEQHGVRPDVISAVSIGAFNGAIVASHPKGATKALEAFWRELSIALPLPYESQWREAWLSSYVLSFGVPNFLKPQWSQLGFDADRLRAKWTSFFDATAIEQLIARYVDFDSLGMSPTRLLIGAVDVETGEPRIFDSYVDRLSPAHVLASGSLPPGMPWTVVDGRPYWDGGVVSNSPLDLVIARCGQIGGRVFIVDLFSGSKALPTNLVEVMLRREEIAYMDRVRNDLRFEEYASDFRDLVDGILAHVDAPSANEIRQQPLYIRLMGNRAAIDIARITLNREGRLSFIEDYDFSSDAIAQLQQQGYDAALVALANGRSRRRRGRRRA
>NC_006349.2|WP_004188830.1|2208979_2210878_+|GMC-family-oxidoreductase
MLGATRSTLWGSRERPRIAAARAPGAAAIRMREEARECAGPRGAGRAPHRATAAGGKTGRRTVRAPSRARVGSNNQKVNRMKQQSYDYDYVVVGSGFGGSVSALRLSEKGYRVLVIEQGRRWTPENLPESTWNLSRWQWRPALGLHGFFSMRFFRHVVVLHGNAVGGGSITYANTLLVPPNKVWREGTWAGLEDWERVMPAHYATAKRMLGVVTNRRMDAADFRLKDMAKLIGVEKSFYPTEVGVFFGDDADAPGTRYADPYFGGAGPERTSCIGCGGCMVGCRHGAKNTLDRNYLYLAERLGAQVREQTKVVDVRPLDARADGAAGYAVEAVSLAAGARGAKSRLTCRGVVFAASSLGTQDLLMRLKEKGSLPRLSDALGKRVRTNAESLIGVRFPKSRVDLSKGVAIGSGIYIDEHTHIEATRYPSGSDTMGLLTTVLTRGAPGGLRVLVWLGALAKLVLTRPLSAWRMIDPRGFARETMIFLCMQTLEGHLTMRLKRRWFWPFSKQLATSGAKIPAYIPAANDFAQKAARALGGVPMTSLTEILLNVPMTAHCMGGAAMARDARDGVCDGRSRVFGYRNMYVCDGSVLGANLGVNPSLTITALAEHAMSHVPAAREQRWDSTAETPVAA
>NC_006349.2|WP_004188488.1|2208722_2208920_+|hypothetical-protein
MAQTPIGAAGAISPSTARSIFLEIGLALAGRPIQVRRNRAPFTHGTPRRRPARGPTARTASPAPV
>NC_006349.2|WP_004205322.1|2207371_2208307_+|LysR-family-transcriptional-regulator
MIQNLRQLDLNLLLVFDALMQEQNLSRAAIRLHMSQPAVSNALTRLRQQLGEPLFTRTARGMTPTAQARTLYEPVRQALYLLQIGLGPQADFEPDTHHLFKLSMNDYGQTVLLPDLLAHIKSRAPNVMLSVQSDDAGSIPAQLTTGTLDLAIDYLHFDNPELCYEPLHEEHLVVIGRAGHPAFAGGLALRGYEESGHVSIQPRDRRGSPLEIVLGSARVRRVVHLQVPHYLTIPALVAKSDLLGTIPRRLAERFADVYALQIAPLPIDIAPIQVSLIWHRQQDAQPGLRWLREQVVLTHRAIIGCGEHAPA
>NC_006349.2|WP_004200700.1|2205958_2207074_-|SRPBCC-family-protein
MTQDVTVFRARYRASVHPRYNAWLHGGFVLAYGCAAIAFFLKDVARVSAVQWASVPAAFLLFNWLEFTVHRHVGHVKRRFGAMFYRRHTGDHHSFFANEQIAYREARDWRVILFPAWLIVVFSLGLFALHAVLGRFDANVAGLFASTMLGGYLLYECVHACEHLPDAHPLAKWPWIRQMRVLHRVHHRDALMRSCNFDVIWPLMDWLHGTLRWSEAPGADMSTRMRHEIDIACAGADVLAYASDASRWPEWHPSSLRVDGPAGSLAAGSRFDEDVRAAGRVDRLHWDVVRNEPGVMWQARAANTAGSLRILLTYECSGGPRGARFVRTLHYHSPNPLLRLANALVMRGRVERESAYSLTLLKRRLEAARDA
>NC_006349.2|WP_004196898.1|2205183_2205624_+|SRPBCC-family-protein
MKQQRIEIAEEFDAPVHQVFRFFSEHENLKSIFSPAKIRRISDGEPARNGVGSAREMRVPGAPPFVETVTAYQENELIEYRITRGSPLRDHLGVMRFVPIDERRTYFHYVITFEGKVPFVAPVVRHVLEGSIRRGLGKVATRRLWG
>NC_006349.2|WP_004200699.1|2202698_2203931_-|3-methyl-2-oxobutanoate-dehydrogenase-(2-methylpropanoyl-transferring)-subunit-alpha
MSQYGPLRLHVPEPTGRPGCKTDFSYLRLSPAGKVRKPPIDVAPADTSDLAYGLVRVLDEHGRAVGPWAPDLDPDILRKGIRAMLKTRIFDARMQIAQRQKKISFYMQCLGEEAIAVAHTLALERGDMCFPTYRQQGILMVREYPLVDMMCQLMSNERDPLKGRQLPVMYSTRDAGFFSISGNLATQFIQAVGWAMASAIKGDTRIASAWIGDGATAEADFHTALTFAHVYRAPVILNVVNNQWAISTFQAIAGGEGATFAGRGVGCGIASLRVDGNDFLAVYAASRWAAERARRNLGPTLIEWVTYRAGPHSTSDDPTKYRPGDDWTNFPLGDPLERLKRHMIGIGVWSEQDHEDTKAALEAEVLAAQKEAERYGMLADEHVPNVASIFEDVYKEMPAHLRRQRQQLGV
>NC_006349.2|WP_004188282.1|2201649_2202693_-|alpha-ketoacid-dehydrogenase-subunit-beta
MTTASKEGPAASPMTMIQALRSAMDVMLERDGNVVVFGQDVGYFGGVFRCTEGLQNKYGKSRVFDAPINEGGIVGAAVGMGAYGLRPVCEIQFADYFYPASDQIVSEAARLRYRSAAEFIAPLTIRMPCGGGIYGGQTHSQSPEAMFTQVCGLRTVMPSNPYDAKGLLISAIENDDPVIFLEPKRLYNGPFDGHHERPVTPWSKHPASLVPDGYYTVPLDSAAIVRAGGDVTVLTYGTTVHVSLAAAEETGIDAEVIDLRSLWPLDLDTIVESVRRTGRCVVVHEATRTCGFGAELIALVQEHCFHWLEAPVERVTGWDTPYPHAQEWAYFPGPNRVGDALRRAMEN
>NC_006349.2|WP_004187057.1|2200196_2201648_-|2-oxo-acid-dehydrogenase-subunit-E2
MGVHVIKMPDIGEGIAEVELGLWHVKVGDRVKEDQATADVMTDKASVEIPSPVTGVVVALGGKEGDVLAVGSELVRLEVEGDGNHKAEPDGGARAAAAQPERVADTAHAHASAAAKSARGEHGAGHGRDDARAASSGTSSGASHTQHAEREARGHRESSEYREDRSVSRGASQTDVERGPASPPPARRPGERPLASPAVRKRAWDLGVELRYVHGTGEAGRILHEDLDAYLQGRGAAAQRARGGQAAYVERHDEEAVPVIGLRRKIAQRMQDAKRRIPHFSYVEEIDVTELEALRAELNRKYGDTRGRLTVLPLLARAMVIALREFPQINARYDDEAGVVTRHGAVHLGIATQSKAGLMVPVVRHAEARDPWSIAAEVARLADAARAGRAERDELSGSTITITSLGALGGIASTPVINSPEVGIVGVNRIVERPMFRGGAVVARKLMNLSSSFDHRVIDGMDAAEFIQAVRALLEQPALLFVE
>NC_006349.2|WP_004188034.1|2215356_2216622_+|polyhydroxyalkanoate-depolymerase
MLYAWLEAQREFFRACQPWAGAAQRAGAGARPAGWPTWGPMARAADAVPAPPPFAIASIEIDGAAVPVDECVVDDTPFCALRKFSRRLRGDAAARPAVFLCTPLAGHHAVMLRETVETILATRDVYVTDWRNARDVPPEAGAFGLDDYVCTLERFVAGAAGDGLHMMAVCQATVPALAAVALLAARDVHVTSVALLGGPVDTRSHPTLIDRFALEHDLDWFRRTAIDIVPPPYAGAGRRVYPGFIQHAAIIVAHPQRRASLESRYWTAWMTGDFAAAARCLREMNEYGAVLDMTERYFLDTIRVIFHERLLAQGRWSIGRRLVAPRRLTRTALCTIEGGRDDIAGAGQTHAAHALCDAVPDAVRERITEPDCDHYDLFLGPRWRRTIHPALDAFWTRAEAARAAAGEPRPTAERAERRIAH
>NC_006349.2|WP_004529492.1|2216870_2218712_+|ribonucleotide-reductase-like-protein
MRTINKRTRTIAHADSFVRMIGDMDDQPICDAVFADRYALPGEHSRAQACARVARALALAEPMATRSGAARRFYRNLLNGAFGAGRIMARAGAAPDQTMASCFVHPIRAPAALTRFHPNLDEALDEARLALAMGADIGYDFSAIPPAGARPDADHPDSPGVCAALDRFDRIGTQAGERDGRRRAQLAVLRCDHPDLLAFAAAKHRHAGRHARWTTLELAVAATDAFMQAVEQDLPWTLRHTAPPRDAPGGALPGADGAWTYASVPARHVWREIVSAARDGAGPGLVFVDAIDAADPLRGRERIDATSPCGAQPLPPYGSAMLGAIDLSRFVRNPFGAGGEPRFDFAAFDTAVRIEVRLLDNALDVTRWPLAAHARESYQKRRIGVGVTGLADMLAMMRLRYDSPAAREMARYIASDLRHHAYAASAELAAERGAYPLCDRHAHLDALRAGPPLPHAVCHAIERDGLRHSHLTSFAPVIGVSLAFGDHCSPGIEPARAWIEHRPVRAGAAGAPGMRAENHAHRLFRSLRGERAALPDYFATDADVAPGERLAMRVALQPYVDAGIDNTLTLANHYSLEEVNALLFAAWRAKLKSVAIRRADLARDAQPSDDDGV
>NC_006349.2|WP_004187710.1|2218786_2220589_+|bifunctional-aminoglycoside-phosphotransferase/ATP-binding-protein
MTTGAVAARRLPRRGTARGRRAPSRAFTIHGGDEMRRSRPPKPAKPAAVRRRPHGAARAHAIRGNGPQRRAVRERAARRLSRDIDAALRRASTYPHPAGPIVRIETHLSVVYLVGRFAYKRLKPFDFGFANFTELAARRRACEAELALNRPLAAPIYLAAGPLVRRARGLRLFGAGAAVDHVVRMRRFDERMLFSRLLARGALDAADIDAAATRLAAYHLHAPRDIPRRAYGSARELRRQLDDMLAPLERALGAALPASLRAWCVRRCDELAAHLDARRADGYVRACHGDLHLNNVVKRGRDALMFDCIDFDDALRWIDVINDLSFLLMDLHAHDRAALAHRLLNRWLDETGDFAGLAALPLYVAYRALVRALVATMRAGGDAAARAARIERARRYVDVAAHAARARRPCLLLCHGYSGSGKSVASRALADVSGAIRLSSDSERKRARPFAAVDARPLPASAYTPQQIDAQYERLRALARDVLRAGYTALVDATFLSHARRARFFALARELGVPVYVLDFHASRACLERRVDARAAARDDRSDAGAAVLATQRASADPLDADERARTIGFDTDVPLATLRSAGYWRPVLDAARVDAQATR
>NC_006349.2|WP_162473582.1|2220722_2221019_+|quinone-oxidoreductase
MPHRTAPHRNGNGNGNGDGNDDRTPPPAGSARAARRADSRANRTRSRAHARRAGEIRRSRGPRRNGHRPRERRPNARSTHRPSAVDLGQSAPAGRSID
>NC_006349.2|WP_004187792.1|2222144_2223977_+|STAS-domain-containing-protein
MTERERAARGRNDARRGGGDSGGDDEAWRRWLPGIATLRTYRRAWLARDLYAGVALTAVLVPVGMSYAQAAGLPVIAGLNASIAALVGYAIFGPSRILVLGPDSALAALIAGAIAPLAHGEPAHAVALAAALALMSGGFCVLAGLLKLGFVTDLLSKPIQYGYLNGLALTLIASQLPSLLGTVPLGGTFVDQVASLAATVAQGRIDFASLALGGGCLAGIALLRRVAPAWPGMLIAVAGASIVAAWLGAAPDAGGAHAHVAYAHVANAHVALVGSLAGTLPPLGLPSISLADASRLIAGALAIAMVSVADISVLSHVFAQHDGSETDRNQELCALGAANLLAGMLRGCAVSSSASRTPVALAAGARTQLTSLVAAACIALLLIAPTLLARVPLAALAAVVVYSANALVDVRAIVRLYRVRRGECAVSVLCFAGVVLLGVVPGILLAVGLSLLSFVWRAWHPYDAVLGRVEGMHGYHDVSRHPGATLTRGLVAFRWDAPLFHANATIFRDHVRDAIAEAGAPVRCVVIAAEPITDVDVTAADMLATLRDELAARRIALVFAEMKGPVKDRLRTYGLFEKIGADHFFPTVTDAIEHFTRMRKDVATARRARR
>NC_006349.2|WP_011204700.1|2224009_2224384_+|hypothetical-protein
MRARAPIRLGGSARLRSVDDDGAGAQAIEAVRRRHGIGHHDAVSVNAAQAARLRAVARTPNCALDRLDAARFAALRIDDVDISVAVALGIDINVAFPLDIDIDATRRETRRDDSIRQSRAFSSK
>NC_006349.2|WP_004187137.1|2224356_2224806_-|CBS-domain-containing-protein
MNAAEICTREVVACRRTDTVLDAAHLMRDRHVGDLIVVDDAGHAHAPVGMLTDRDIVLSLIAKEVDPAALFVGEIMSAPAAVVHEHDSLWTIAQRMRLTGVRRMPVVNADGALVGMVSVDDLLASVAALFDEIASISRRQIHFEEKARD
>NC_006349.2|WP_004200705.1|2225259_2225913_+|SagB/ThcOx-family-dehydrogenase
MSDPELLTYQPIAVALPGPAEAGAPAVIDLPPPDLGAGLPLMSALSLRASTREFSSAALAPTTLGELLWAADGVNRPTTGGRTAPSAHAFNEIDIYAALPDGVYRYDAALHRLLLKHAVDARNLTGYQDFVGAAPLDLIYVVRMSRLLSMPKPLRETFSAVAAGAIAQNVALYCASTGLGCVVRGWINHRLLAEALSLNEDELPILAQTVGKPAAHP
>NC_006349.2|WP_011204701.1|2225980_2226415_-|Hsp20/alpha-crystallin-family-protein
MSNVTRYDPFSLEPVSDLFRGLFRPLRGIADADDEKLASMKIDVTENDQAYAVKAELPGVDKNDINVQIDGNTVSISAKVERNKELKEGERVIRRERYSGEFARTFSLANELDRDAASAQYQDGVLSLTLPKKASSEKKKLTIG
>NC_006349.2|WP_004188244.1|2226820_2227951_-|porin
MMNAKSIAAAALAVAQAGLAHAQSSVTLYGALDAGVLWQNTSAASFSPTAPNTGAVVRFKDGGVYSSLWGIKGTEDLGGGYRVNFRLQGAFDGGTGKFGLSDAPGAVAAFNQIATLGVSGPFGTFNAGRQIVPMIYAMADTDVRAARFFGSVLTAWLGLNTAAGWPGNSTNAPIGALYDSDALVYQSPAFGGASLALEYAPGGVPGGVQRGARASIVLKYASNALNLAAVYYNGHDTNPAPGASATGLDNNRFVYVGAQYKLKDVAVSASYGNGRNPARGDRVNLDMFAFGLGYRVSPFFRVSSGVYYLKDRNRSANRSTSIVLGADYELSKHTTLYAQGGRVDNRGTMAQMLAYGQPVAPGLATTAAMLGMRHSF

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Click the colored protein region to show detailed information

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

384322 : 434026

Leptospira_phage(25.0%)

transposase,plate

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_004190585.1\|384322_385726_+\|plate	type VI secretion system baseplate subunit TssK	NA	NA	NA	NA
WP_004190689.1\|385741_387058_+	DotU family type VI secretion system protein	NA	NA	NA	NA
WP_004190681.1\|387060_390690_+	type VI secretion system membrane subunit TssM	NA	NA	NA	NA
WP_004190273.1\|391586_391814_-	hypothetical protein	NA	NA	NA	NA
WP_004190797.1\|391812_394410_+	protein kinase	M1I231	Acanthocystis_turfacea_Chlorella_virus	5.0e-09	26.6
WP_004190988.1\|394462_395542_+	type VI secretion system protein TssA	NA	NA	NA	NA
WP_004190671.1\|395604_396183_+	type VI secretion system contractile sheath small subunit	NA	NA	NA	NA
WP_004190849.1\|396175_397684_+	type VI secretion system contractile sheath large subunit	NA	NA	NA	NA
WP_004190698.1\|397743_398235_+	type VI secretion system tube protein Hcp	NA	NA	NA	NA
WP_004196148.1\|398253_398814_+\|plate	type VI secretion system baseplate subunit TssE	NA	NA	NA	NA
WP_004190509.1\|398818_400690_+\|plate	type VI secretion system baseplate subunit TssF	NA	NA	NA	NA
WP_004196149.1\|400686_402177_+\|plate	type VI secretion system baseplate subunit TssG	NA	NA	NA	NA
WP_004190714.1\|402155_404810_+	type VI secretion system ATPase TssH	K4FB40	Cronobacter_phage	2.3e-78	30.8
WP_004203275.1\|404806_407011_+	type VI secretion system tip protein VgrG	A0A077K8Q4	Ralstonia_phage	9.6e-46	29.9
WP_004196151.1\|407085_407739_+	hypothetical protein	NA	NA	NA	NA
WP_004196154.1\|407668_408727_+	RHS repeat protein	NA	NA	NA	NA
WP_038802950.1\|408754_409875_-\|transposase	IS3 family transposase	S5WIU1	Leptospira_phage	3.6e-49	39.5
WP_011204340.1\|410548_411529_-	methyltransferase domain-containing protein	NA	NA	NA	NA
WP_004190776.1\|412045_413470_+	cytosine permease	NA	NA	NA	NA
WP_004190245.1\|413466_414405_+	NAD-dependent protein deacetylase	S5M4R0	Bacillus_phage	1.4e-14	25.3
WP_004190461.1\|414367_415045_+	DUF938 domain-containing protein	NA	NA	NA	NA
WP_004190588.1\|415368_415512_-	hypothetical protein	NA	NA	NA	NA
WP_004190614.1\|415500_416916_+	NADP-dependent phosphogluconate dehydrogenase	M4QQM4	Ostreococcus_lucimarinus_virus	2.1e-41	30.2
WP_011204342.1\|417114_417447_+	DUF4148 domain-containing protein	NA	NA	NA	NA
WP_004196156.1\|417840_418203_+	cupin	NA	NA	NA	NA
WP_011204344.1\|418481_419246_+	peptidoglycan DD-metalloendopeptidase family protein	NA	NA	NA	NA
WP_004190805.1\|419376_420012_-	Pr6Pr family membrane protein	NA	NA	NA	NA
WP_004190603.1\|420280_420817_+	cytochrome b	NA	NA	NA	NA
WP_004190837.1\|420977_421373_+	DUF2946 domain-containing protein	NA	NA	NA	NA
WP_004190808.1\|421460_423698_+	TonB-dependent copper receptor	NA	NA	NA	NA
WP_004196164.1\|424048_425074_+	triacylglycerol lipase	NA	NA	NA	NA
WP_004190433.1\|425118_426153_+	lipase secretion chaperone	NA	NA	NA	NA
WP_004200631.1\|426254_427784_-	PLP-dependent aminotransferase family protein	NA	NA	NA	NA
WP_004190757.1\|427892_428993_+	ABC transporter ATP-binding protein	G3M9Y6	Bacillus_virus	5.2e-24	31.5
WP_004190781.1\|429067_430114_+	ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_004196172.1\|430214_431474_+	ABC transporter permease	NA	NA	NA	NA
WP_038802950.1\|432905_434026_-\|transposase	IS3 family transposase	S5WIU1	Leptospira_phage	3.6e-49	39.5

DBSCAN-SWA_2

437266 : 510578

Bacillus_phage(25.0%)

holin,transposase,plate

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_004196180.1\|437266_439129_+\|plate	type VI secretion system baseplate subunit TssF	NA	NA	NA	NA
WP_004190851.1\|439125_440115_+\|plate	type VI secretion system baseplate subunit TssG	NA	NA	NA	NA
WP_004196185.1\|442978_445225_+	type VI secretion system tip protein VgrG	NA	NA	NA	NA
WP_004190563.1\|445390_447679_+	type VI secretion system tip protein VgrG	NA	NA	NA	NA
WP_004200633.1\|447682_449899_+	pentapeptide repeat-containing protein	NA	NA	NA	NA
WP_004202229.1\|449898_450969_+	pentapeptide repeat-containing protein	NA	NA	NA	NA
WP_004266663.1\|450971_451688_+	DUF3540 domain-containing protein	NA	NA	NA	NA
WP_004190606.1\|451730_452120_+	DUF4150 domain-containing protein	NA	NA	NA	NA
WP_004196199.1\|452304_453450_+\|plate	type VI secretion system baseplate subunit TssK	NA	NA	NA	NA
WP_004206248.1\|453468_454077_+\|plate	type VI secretion system baseplate subunit TssK	NA	NA	NA	NA
WP_004190463.1\|454159_455818_+	DotU family type IV/VI secretion system protein	NA	NA	NA	NA
WP_004190265.1\|455814_459318_+	type VI secretion system membrane subunit TssM	NA	NA	NA	NA
WP_004190863.1\|459376_459736_+	hypothetical protein	NA	NA	NA	NA
WP_004190471.1\|459758_460184_+	hypothetical protein	NA	NA	NA	NA
WP_004190745.1\|460504_460780_+	hypothetical protein	NA	NA	NA	NA
WP_004186983.1\|461330_462230_+	alpha/beta hydrolase	NA	NA	NA	NA
WP_004201077.1\|462271_462562_-	hypothetical protein	NA	NA	NA	NA
WP_004186962.1\|462451_463771_+	glycosyltransferase	NA	NA	NA	NA
WP_004184379.1\|463767_465354_+	DHA2 family efflux MFS transporter permease subunit	NA	NA	NA	NA
WP_004186828.1\|465618_466614_+	glycosyltransferase family 2 protein	NA	NA	NA	NA
WP_004196352.1\|466918_468514_+	efflux transporter outer membrane subunit	NA	NA	NA	NA
WP_004186853.1\|468994_470248_+	efflux RND transporter periplasmic adaptor subunit	NA	NA	NA	NA
WP_004198244.1\|470849_472514_-	glycoside hydrolase family 32 protein	F8WPR5	Bacillus_phage	5.4e-57	31.4
WP_004186967.1\|472646_474131_-	glycoside hydrolase family 68 protein	NA	NA	NA	NA
WP_004186794.1\|474400_475417_+	substrate-binding domain-containing protein	NA	NA	NA	NA
WP_004186783.1\|475856_477056_+	formaldehyde dehydrogenase, glutathione-independent	A0A2K9L7I1	Tupanvirus	1.9e-11	26.8
WP_004198247.1\|477233_478259_-	GlxA family transcriptional regulator	NA	NA	NA	NA
WP_162473486.1\|478272_478557_+	hypothetical protein	NA	NA	NA	NA
WP_004186965.1\|478692_479967_+	serine hydroxymethyltransferase	A0A219Y950	Aeromonas_phage	6.9e-105	54.1
WP_004186989.1\|480039_481011_+	membrane dipeptidase	NA	NA	NA	NA
WP_004186987.1\|481161_481695_+	4-vinyl reductase	NA	NA	NA	NA
WP_004186960.1\|481755_483819_+	NADH:flavin oxidoreductase	NA	NA	NA	NA
WP_004186901.1\|483821_485747_+	(Fe-S)-binding protein	NA	NA	NA	NA
WP_004186905.1\|485751_486924_+	electron transfer flavoprotein subunit alpha/FixB family protein	NA	NA	NA	NA
WP_004186884.1\|486920_487706_+	drug:proton antiporter	NA	NA	NA	NA
WP_004186879.1\|487730_488999_+	aromatic ring-hydroxylating dioxygenase subunit alpha	NA	NA	NA	NA
WP_004186910.1\|489019_490165_+	hybrid-cluster NAD(P)-dependent oxidoreductase	NA	NA	NA	NA
WP_004186918.1\|490274_491138_+	glycine betaine ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_004186811.1\|491318_492974_+	APC family permease	NA	NA	NA	NA
WP_004186920.1\|493060_493936_-	formyltetrahydrofolate deformylase	NA	NA	NA	NA
WP_021252052.1\|494079_494952_-	LysR family transcriptional regulator	NA	NA	NA	NA
WP_004186939.1\|495114_496668_+\|holin	choline-sulfatase	NA	NA	NA	NA
WP_004186847.1\|496664_497558_+	glycine/betaine ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_004198249.1\|497554_497677_+	hypothetical protein	NA	NA	NA	NA
WP_004200640.1\|497785_498928_+	porin	NA	NA	NA	NA
WP_004200641.1\|498982_500209_-	M20/M25/M40 family metallo-hydrolase	NA	NA	NA	NA
WP_004198575.1\|500326_502030_-	M36 family metallopeptidase	NA	NA	NA	NA
WP_004186852.1\|502501_503446_-	GlxA family transcriptional regulator	NA	NA	NA	NA
WP_011204354.1\|503713_504664_+\|holin	choline ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_004186835.1\|504746_505676_+	3-keto-5-aminohexanoate cleavage protein	NA	NA	NA	NA
WP_024900416.1\|505790_506756_+	L-carnitine dehydrogenase	NA	NA	NA	NA
WP_004200643.1\|506758_507256_+	thioesterase family protein	NA	NA	NA	NA
WP_004186844.1\|507291_508251_+	alpha/beta hydrolase	NA	NA	NA	NA
WP_004543123.1\|508597_508906_-	DUF4148 domain-containing protein	NA	NA	NA	NA
WP_038802950.1\|509457_510578_-\|transposase	IS3 family transposase	S5WIU1	Leptospira_phage	3.6e-49	39.5

DBSCAN-SWA_3

869776 : 911023

Leptospira_phage(50.0%)

transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_038802950.1\|869776_870897_-\|transposase	IS3 family transposase	S5WIU1	Leptospira_phage	3.6e-49	39.5
WP_004198724.1\|871918_873973_-	sugar phosphate isomerase/epimerase and 4-hydroxyphenylpyruvate domain-containing protein	NA	NA	NA	NA
WP_004204041.1\|874232_874688_+	type II 3-dehydroquinate dehydratase	NA	NA	NA	NA
WP_004198727.1\|874684_875539_+	shikimate dehydrogenase	NA	NA	NA	NA
WP_004194588.1\|875586_876933_+	MFS transporter	NA	NA	NA	NA
WP_004194610.1\|877186_878296_-	2-aminoethylphosphonate--pyruvate transaminase	NA	NA	NA	NA
WP_004194640.1\|878533_879616_+	2-aminoethylphosphonate ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_004194602.1\|879672_880770_+	2-aminoethylphosphonate ABC transport system ATP-binding subunit PhnT	G3M9Y6	Bacillus_virus	5.5e-26	32.5
WP_004194612.1\|880747_881695_+	2-aminoethylphosphonate ABC transporter permease subunit	NA	NA	NA	NA
WP_004194685.1\|881684_882545_+	2-aminoethylphosphonate ABC transport system, membrane component PhnV	NA	NA	NA	NA
WP_004199121.1\|882588_883860_+	phosphonoacetate hydrolase	NA	NA	NA	NA
WP_004194628.1\|883856_885311_+	phosphonoacetaldehyde dehydrogenase	NA	NA	NA	NA
WP_004194622.1\|885315_885867_+	HD domain-containing protein	A0A2K9L141	Tupanvirus	2.3e-20	34.1
WP_038802950.1\|892020_893141_-\|transposase	IS3 family transposase	S5WIU1	Leptospira_phage	3.6e-49	39.5
WP_004198117.1\|893311_893458_+	DUF3563 family protein	NA	NA	NA	NA
WP_011204222.1\|893582_895046_-\|transposase	IS1182-like element ISBma2 family transposase	A0A1X9I5T2	Streptococcus_phage	2.0e-79	38.3
WP_004198119.1\|895254_895533_+	hypothetical protein	NA	NA	NA	NA
WP_004198120.1\|895545_896391_-	23S rRNA (adenine(2030)-N(6))-methyltransferase RlmJ	NA	NA	NA	NA
WP_004198121.1\|896539_897511_-	aldo/keto reductase	NA	NA	NA	NA
WP_004204588.1\|897698_898487_+	3-hydroxybutyrate dehydrogenase	NA	NA	NA	NA
WP_004191998.1\|898691_900155_-\|transposase	IS1182-like element ISBma2 family transposase	A0A1X9I5T2	Streptococcus_phage	8.8e-80	38.6
WP_004198124.1\|900298_901498_-	aspartate/tyrosine/aromatic aminotransferase	NA	NA	NA	NA
WP_004199587.1\|901785_903876_+	excinuclease ABC subunit UvrB	NA	NA	NA	NA
WP_004266710.1\|904099_904651_+	iron transporter	NA	NA	NA	NA
WP_004198127.1\|904710_905040_+	cupredoxin domain-containing protein	NA	NA	NA	NA
WP_004198128.1\|905099_905942_+	FTR1 family protein	NA	NA	NA	NA
WP_004198129.1\|905938_907339_+	4Fe-4S binding protein	NA	NA	NA	NA
WP_004199588.1\|907398_907809_+	heme-binding protein	NA	NA	NA	NA
WP_038802950.1\|907954_909074_+\|transposase	IS3 family transposase	S5WIU1	Leptospira_phage	3.6e-49	39.5
WP_038802950.1\|909902_911023_-\|transposase	IS3 family transposase	S5WIU1	Leptospira_phage	3.6e-49	39.5

DBSCAN-SWA_4

1014423 : 1094684

Leptospira_phage(40.0%)

protease,transposase,integrase

attL 1014356:1014415|attR 1097906:1099142

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
1014356:1014415	attL	NA	NA	NA	NA
WP_038802950.1\|1014423_1015543_+\|transposase	IS3 family transposase	S5WIU1	Leptospira_phage	3.6e-49	39.5
WP_004202536.1\|1015757_1020554_-	DEAD/DEAH box helicase	NA	NA	NA	NA
WP_004551771.1\|1021078_1021597_-	hypothetical protein	NA	NA	NA	NA
WP_004184606.1\|1021926_1022445_-	metal-dependent hydrolase	NA	NA	NA	NA
WP_004184536.1\|1023312_1025034_+	gamma-glutamyltransferase	NA	NA	NA	NA
WP_004201091.1\|1025230_1026547_-	TolC family protein	NA	NA	NA	NA
WP_004184472.1\|1026939_1027113_+	hypothetical protein	NA	NA	NA	NA
WP_004184640.1\|1027359_1027545_+	hypothetical protein	NA	NA	NA	NA
WP_004184575.1\|1027681_1029805_+	peptidase domain-containing ABC transporter	W8CYL7	Bacillus_phage	2.5e-27	24.9
WP_004184588.1\|1029801_1030824_+	hypothetical protein	NA	NA	NA	NA
WP_004528592.1\|1030836_1032132_+	HlyD family efflux transporter periplasmic adaptor subunit	NA	NA	NA	NA
WP_038802950.1\|1034024_1035144_+\|transposase	IS3 family transposase	S5WIU1	Leptospira_phage	3.6e-49	39.5
WP_004184552.1\|1036310_1037027_-	TetR/AcrR family transcriptional regulator	NA	NA	NA	NA
WP_004184355.1\|1037105_1038404_+	FAD-dependent oxidoreductase	NA	NA	NA	NA
WP_076841794.1\|1038573_1039017_+	divalent metal cation transporter	NA	NA	NA	NA
WP_004528582.1\|1039120_1040191_-	DMT family transporter	NA	NA	NA	NA
WP_004536930.1\|1040326_1040917_-	YigZ family protein	A0A1X9I5T8	Streptococcus_phage	5.8e-22	39.4
WP_038730458.1\|1040937_1041222_-	hypothetical protein	NA	NA	NA	NA
WP_004184214.1\|1041694_1042219_-	sigma-70 family RNA polymerase sigma factor	NA	NA	NA	NA
WP_004197859.1\|1042248_1042479_-	hypothetical protein	NA	NA	NA	NA
WP_004197860.1\|1042886_1044647_+	fatty acyl-AMP ligase	NA	NA	NA	NA
WP_004184602.1\|1044643_1046404_+	acyl-CoA dehydrogenase	NA	NA	NA	NA
WP_004184547.1\|1046400_1048194_+	acyl-CoA dehydrogenase	NA	NA	NA	NA
WP_004184201.1\|1048204_1048495_+	acyl carrier protein	NA	NA	NA	NA
WP_004184597.1\|1048929_1049733_+	2OG-Fe dioxygenase family protein	NA	NA	NA	NA
WP_038802950.1\|1061800_1062921_-\|transposase	IS3 family transposase	S5WIU1	Leptospira_phage	3.6e-49	39.5
WP_004197866.1\|1063330_1063603_+	DUF4148 domain-containing protein	NA	NA	NA	NA
WP_004184766.1\|1063715_1065110_-	heavy metal sensor histidine kinase IrlS	W8CYF6	Bacillus_phage	1.2e-20	28.9
WP_004197868.1\|1065106_1065796_-	heavy metal response regulator transcription factor IrlR	W8CYM9	Bacillus_phage	1.7e-36	36.8
WP_004197870.1\|1065802_1069036_-	CusA/CzcA family heavy metal efflux RND transporter	NA	NA	NA	NA
WP_004197872.1\|1069081_1070551_-	efflux RND transporter periplasmic adaptor subunit	NA	NA	NA	NA
WP_004197873.1\|1070561_1071947_-	TolC family protein	NA	NA	NA	NA
WP_004197875.1\|1072182_1072467_-	hypothetical protein	NA	NA	NA	NA
WP_004524134.1\|1072864_1073005_-	bacteriophage protein	NA	NA	NA	NA
WP_004197879.1\|1073657_1074146_-	adenosine-specific kinase	NA	NA	NA	NA
WP_004197880.1\|1074472_1074958_+	YbaK/EbsC family protein	NA	NA	NA	NA
WP_004184790.1\|1075225_1076581_+	amino acid permease	NA	NA	NA	NA
WP_004197883.1\|1076880_1077489_+\|protease	rhomboid family intramembrane serine protease	NA	NA	NA	NA
WP_004199606.1\|1077613_1079614_-\|protease	ATP-dependent zinc metalloprotease FtsH	E5EQU5	Bathycoccus_sp._RCC1105_virus	1.1e-104	46.2
WP_011204480.1\|1080986_1082753_+	amidohydrolase family protein	NA	NA	NA	NA
WP_004199157.1\|1082883_1083555_-	transcriptional regulator	NA	NA	NA	NA
WP_004184876.1\|1083705_1084803_+	efflux RND transporter periplasmic adaptor subunit	NA	NA	NA	NA
WP_004199160.1\|1084799_1087901_+	efflux RND transporter permease subunit	S5VTK5	Leptospira_phage	3.6e-46	22.0
WP_004266238.1\|1088035_1089574_+	efflux RND transporter outer membrane subunit OprB	NA	NA	NA	NA
WP_004184915.1\|1089588_1089885_+	hypothetical protein	NA	NA	NA	NA
WP_004199609.1\|1089930_1090548_+	GTP cyclohydrolase II	A0A2H4PQS2	Staphylococcus_phage	6.9e-34	44.6
WP_004197695.1\|1090544_1092242_+	WD40 repeat domain-containing protein	NA	NA	NA	NA
WP_004197696.1\|1092238_1092919_+	1,6-didemethyltoxoflavin N1-methyltransferase	NA	NA	NA	NA
WP_024900397.1\|1092992_1094684_-\|integrase	tyrosine-type recombinase/integrase	NA	NA	NA	NA
1097906:1099142	attR	NA	NA	NA	NA

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

2. NC_006348

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Crispr_ID: NC_006348_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_006348_1

3187717-3187909

Orphan

Consensus_repeat	Method
CGCCGCCGCCACCGCCGCCGCCACCGCCGCCACCGCCGCC	PILER-CR

2 spacers

The CRISPR arrays of NC_006348_1

>merge|NC_006348|1|3187717-3187909|PILER-CR
CGCCGCCACCGCCGCCGCCACCGCCGCCGCCGCCGCCGCCGCTGCGCGCACCCGCGCCGCCGCCACCCGACGCGCGGCCGCCACCGCCGCCGCGCTCCATGTCCCGGCCGCCGCCGTAACCGCCGCCGCCGCCACCGTAGCCGCCGTCGTCACCGCCGCCGCCACCGCCGCCGCCACCGCCGCCACCGCCGCC

>NC_006348|1|1|3187717-3187909|PILER-CR
CGCCGCCACCGCCGCCGCCACCGCCGCCGCCGCCGCCGCC	GCTGCGCGCACCCGCGCCGCCGCCACCCGACGCGC
GGCCGCCACCGCCGCCGCGCTCCATGTCCCGGCCGCCGCC	GTAACCGCCGCCGCCGCCACCGTAGCCGCCGTCGTCACCGCCGCCGCCACCGCCGCCGCC
ACCGCCGCCACCGCCGCC

Protein	Signature genes	Signature genes Name	Protein_function
NC_006348.1\|WP_004195195.1\|3192851_3193937_+\|membrane-protein	unknown	unknown	gnl\|CDD\|223701
NC_006348.1\|WP_004193486.1\|3177176_3178373_+\|MFS-transporter	unknown	unknown	gnl\|CDD\|340882
NC_006348.1\|WP_004195180.1\|3180109_3180901_-\|molybdopterin-dependent-oxidoreductase	unknown	unknown	gnl\|CDD\|239026
NC_006348.1\|WP_004195184.1\|3182043_3182868_-\|DUF1223-domain-containing-protein	unknown	unknown	gnl\|CDD\|369071
NC_006348.1\|WP_004192284.1\|3178720_3179656_-\|EamA-family-transporter	unknown	unknown	gnl\|CDD\|183067
NC_006348.1\|WP_004193339.1\|3183028_3183334_-\|pentapeptide-MXKDX-repeat-protein	unknown	unknown	gnl\|CDD\|131998
NC_006348.1\|WP_004193824.1\|3175567_3175978_-\|hypothetical-protein	unknown	unknown	unknown
NC_006348.1\|WP_004200146.1\|3200479_3201019_+\|HAD-family-hydrolase	unknown	unknown	gnl\|CDD\|224692
NC_006348.1\|WP_004195199.1\|3195165_3196023_-\|DUF4743-domain-containing-protein	unknown	unknown	gnl\|CDD\|239648
NC_006348.1\|WP_038802950.1\|3186053_3187174_-\|IS3-family-transposase	unknown	unknown	gnl\|CDD\|372671
NC_006348.1\|WP_004195190.1\|3188364_3189552_-\|MFS-transporter	unknown	unknown	gnl\|CDD\|341025
NC_006348.1\|WP_004193963.1\|3183983_3185915_+\|phosphomethylpyrimidine-synthase-ThiC	unknown	unknown	gnl\|CDD\|236451
NC_006348.1\|WP_004195200.1\|3196035_3196620_-\|LysE-family-translocator	unknown	unknown	gnl\|CDD\|224199
NC_006348.1\|WP_004195206.1\|3199496_3200480_+\|KpsF/GutQ-family-sugar-phosphate-isomerase	unknown	unknown	gnl\|CDD\|182814
NC_006348.1\|WP_004195204.1\|3197359_3199369_-\|potassium-efflux-system-protein	unknown	unknown	gnl\|CDD\|235131
NC_006348.1\|WP_004195210.1\|3201024_3201639_+\|LPS-export-ABC-transporter-periplasmic-protein-LptC	unknown	unknown	gnl\|CDD\|275202
NC_006348.1\|WP_004195192.1\|3189765_3192633_+\|excinuclease-ABC-subunit-UvrA	unknown	unknown	gnl\|CDD\|234734
NC_006348.1\|WP_004195197.1\|3194232_3195114_-\|formyltetrahydrofolate-deformylase	unknown	unknown	gnl\|CDD\|235676
NC_006348.1\|WP_004195181.1\|3180916_3182053_-\|cytochrome-b/b6-domain-containing-protein	unknown	unknown	gnl\|CDD\|226602
NC_006348.1\|WP_004192698.1\|3176109_3176862_-\|membrane-protein	unknown	unknown	gnl\|CDD\|227049

Protein	Function_ID	Function_description	E-value
NC_006348.1\|WP_004195195.1\|3192851_3193937_+\|membrane-protein	gnl\|CDD\|223701	COG0628, yhhT, Predicted permease, member of the PurR regulon [General function prediction only].	3.14277e-15
NC_006348.1\|WP_004193486.1\|3177176_3178373_+\|MFS-transporter	gnl\|CDD\|340882	cd17324, MFS_NepI_like, Purine ribonucleoside efflux pump NepI and similar transporters of the Major Facilitator Superfamily. This family is composed of purine efflux pumps such as Escherichia coli NepI and Bacillus subtilis PbuE, sugar efflux transporters such as Corynebacterium glutamicum arabinose efflux permease, multidrug resistance (MDR) transporters such as Streptomyces lividans chloramphenicol resistance protein (CmlR), and similar proteins. NepI and PbuE are involved in the efflux of purine ribonucleosides such as guanosine, adenosine and inosine, as well as purine bases like guanine, adenine, and hypoxanthine, and purine base analogs. They play a role in the maintenance of cellular purine base pools, as well as in protecting the cells and conferring resistance against toxic purine base analogs such as 6-mercaptopurine. MDR transporters are drug/H+ antiporters (DHA) that mediate the efflux of a variety of drugs and toxic compounds, and confer resistance to these compounds. The NepI-like family belongs to the Major Facilitator Superfamily (MFS) of membrane transport proteins, which are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	8.94618e-60
NC_006348.1\|WP_004195180.1\|3180109_3180901_-\|molybdopterin-dependent-oxidoreductase	gnl\|CDD\|239026	cd02108, bact_SO_family_Moco, bacterial subgroup of the sulfite oxidase (SO) family of molybdopterin binding domains. This domain is found in a variety of oxidoreductases. Common features of all known members of this family, like sulfite oxidase and nitrite reductase, are that they contain one single pterin cofactor and part of the coordination of the metal (Mo) is a cysteine ligand of the protein and that they catalyze the transfer of an oxygen to or from a lone pair of electrons on the substrate. The specific function of this subgroup is unknown.	1.58666e-90
NC_006348.1\|WP_004195184.1\|3182043_3182868_-\|DUF1223-domain-containing-protein	gnl\|CDD\|369071	pfam06764, DUF1223, Protein of unknown function (DUF1223). This family consists of several hypothetical proteins of around 250 residues in length which are found in both plants and bacteria. The function of this family is unknown. Structurally it lies in the Thioredoxin-like superfamily.	3.14399e-68
NC_006348.1\|WP_004192284.1\|3178720_3179656_-\|EamA-family-transporter	gnl\|CDD\|183067	PRK11272, PRK11272, putative DMT superfamily transporter inner membrane protein; Provisional.	4.46808e-57
NC_006348.1\|WP_004193339.1\|3183028_3183334_-\|pentapeptide-MXKDX-repeat-protein	gnl\|CDD\|131998	TIGR02953, conserved_hypothetical_protein, pentapeptide MXKDX repeat protein. Members of this protein family are small bacterial proteins, each with an N-terminal signal sequence followed by up to 11 imperfect repeats of a pentapeptide. The pentapeptide repeat usually follows the form Met-Xaa-Lys-Asp-Xaa.	0.000353246
NC_006348.1\|WP_004200146.1\|3200479_3201019_+\|HAD-family-hydrolase	gnl\|CDD\|224692	COG1778, COG1778, Low specificity phosphatase (HAD superfamily) [General function prediction only].	1.33155e-78
NC_006348.1\|WP_004195199.1\|3195165_3196023_-\|DUF4743-domain-containing-protein	gnl\|CDD\|239648	cd03676, Nudix_hydrolase_3, Members of the Nudix hydrolase superfamily catalyze the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes belong to this superfamily requires a divalent cation, such as Mg2+ or Mn2+, for their activity and contain a highly conserved 23-residue nudix motif (GX5EX7REUXEEXGU, where U = I, L or V), which functions as a metal binding and catalytic site. Substrates of nudix hydrolases include intact and oxidatively damaged nucleoside triphosphates, dinucleoside polyphosphates, nucleotide-sugars and dinucleotide enzymes. These substrates are metabolites or cell signaling molecules that require regulation during different stages of the cell cycle or during periods of stress. In general, the role of the nudix hydrolase is to sanitize the nucleotide pools and to maintain cell viability, thereby serving as surveillance & "house-cleaning" enzymes. Substrate specificity is used to define families within the superfamily. Differences in substrate specificity are determined by the N-terminal extension or by residues in variable loop regions. Mechanistically, substrate hydrolysis occurs by a nucleophilic substitution reaction, with variation in the numbers and roles of divalent cations required.	6.89631e-81
NC_006348.1\|WP_038802950.1\|3186053_3187174_-\|IS3-family-transposase	gnl\|CDD\|372671	pfam13683, rve_3, Integrase core domain.	2.07519e-34
NC_006348.1\|WP_004195190.1\|3188364_3189552_-\|MFS-transporter	gnl\|CDD\|341025	cd17472, MFS_YajR_like, Escherichia coli inner membrane transport protein YajR and similar multidrug-efflux transporters of the Major Facilitator Superfamily. This family is composed of Escherichia coli inner membrane transport protein YajR and some uncharacterized multidrug-efflux transporters. YajR is a putative proton-driven major facilitator superfamily (MFS) transporter found in many gram-negative bacteria. Unlike most MFS transporters, YajR contains a C-terminal, cytosolic YAM domain, which may play an essential role for the proper functioning of the transporter. YajR-like transporters belong to the Major Facilitator Superfamily (MFS) of membrane transport proteins, which are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	3.31309e-122
NC_006348.1\|WP_004193963.1\|3183983_3185915_+\|phosphomethylpyrimidine-synthase-ThiC	gnl\|CDD\|236451	PRK09284, PRK09284, thiamine biosynthesis protein ThiC; Provisional.	0
NC_006348.1\|WP_004195200.1\|3196035_3196620_-\|LysE-family-translocator	gnl\|CDD\|224199	COG1280, RhtB, Putative threonine efflux protein [Amino acid transport and metabolism].	5.1192e-37
NC_006348.1\|WP_004195206.1\|3199496_3200480_+\|KpsF/GutQ-family-sugar-phosphate-isomerase	gnl\|CDD\|182814	PRK10892, PRK10892, arabinose-5-phosphate isomerase KdsD.	1.26452e-136
NC_006348.1\|WP_004195204.1\|3197359_3199369_-\|potassium-efflux-system-protein	gnl\|CDD\|235131	PRK03562, PRK03562, glutathione-regulated potassium-efflux system protein KefC; Provisional.	2.37135e-95
NC_006348.1\|WP_004195210.1\|3201024_3201639_+\|LPS-export-ABC-transporter-periplasmic-protein-LptC	gnl\|CDD\|275202	TIGR04409, LptC_YrbK, LPS export ABC transporter periplasmic protein LptC. Members of this family are LptC, a periplasmic protein tethered to the inner membrane in the lipopolysaccharide (LPS)exporter transenvelope complex (Lpt), which is responsible for conducting LPS to the outer leaflet of the outer membrane in most Gram-negative bacteria. LptC is homologous to LptA, another member of the transenvelope complex. Genes lptC and lptA are often adjacent. [Cell envelope, Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides, Transport and binding proteins, Other].	4.08373e-55
NC_006348.1\|WP_004195192.1\|3189765_3192633_+\|excinuclease-ABC-subunit-UvrA	gnl\|CDD\|234734	PRK00349, uvrA, excinuclease ABC subunit UvrA.	0
NC_006348.1\|WP_004195197.1\|3194232_3195114_-\|formyltetrahydrofolate-deformylase	gnl\|CDD\|235676	PRK06027, purU, formyltetrahydrofolate deformylase; Reviewed.	0
NC_006348.1\|WP_004195181.1\|3180916_3182053_-\|cytochrome-b/b6-domain-containing-protein	gnl\|CDD\|226602	COG4117, COG4117, Thiosulfate reductase cytochrome B subunit (membrane anchoring protein) [Energy production and conversion].	3.43617e-56
NC_006348.1\|WP_004192698.1\|3176109_3176862_-\|membrane-protein	gnl\|CDD\|227049	COG4705, COG4705, Uncharacterized membrane-anchored protein conserved in bacteria [Function unknown].	7.15424e-88

>NC_006348.1|WP_038802950.1|3186053_3187174_-|IS3-family-transposase
MKKRFTEQQIIGFLKEAEAGMPVKELCRKHGFSDASFYTWRAKFGGMEVSEARRLKGLEVENARLKKLLAEAMLDMEALKVVVKGKPLSPQAKREAVLAIREKVNISERRACRLVGLSRSVLHYDAKPDHENEVLAARLVKLAHERRRFGYRRLHALVEREGTHANHKRIYRLYREAGLAVRRRRKRHGVMIEREQLALPGAPNEVWSIDFVMDALSNGRRVKCLTVVDDFTKEAVDIVVDHGISGLYVARALDRAARFRGYPKAVRTDQGPEFTSRALDQWAYANGVTLKLIQAGKPTQNAYIESFNGKFRDECLNEHWFTTLAHARAVIAAWRQDYNEQRPHSALNYLAPSEFAAKHRATADAPAAFQELV
>NC_006348.1|WP_004193963.1|3183983_3185915_+|phosphomethylpyrimidine-synthase-ThiC
MNANPKFLSADARVDAAAVAPLPNSRKVYVTGSQPDIRVPMREITQADTPTSFGGEKNPPIYVYDTSGPYTDPDAKIDIRAGLPALRQRWIDARGDTETLSGLTSDYGRERAADPATAELRFPGLHRHPRRAKAGKNVTQMHYARQGIITPEMEYIAIRENQRRAEYLESLKASGPNGAKLAAMMGRQHAGQAFGAAAFGANAPAEITPEFVRDEVARGRAIIPANINHPETEPMIIGRNFLVKINANIGNSAVTSSIGEEVDKMTWAIRWGGDTVMDLSTGKHIHETREWIIRNSPVPIGTVPIYQALEKVNGKAEDLTWEIFRDTLIEQAEQGVDYFTIHAGVRLQYVPLTANRMTGIVSRGGSIMAKWCLAHHKESFLYEHFEEICEIMKAYDVSFSLGDGLRPGSIYDANDEAQLGELKTLGELTQIAWKHDVQVMIEGPGHVPMQLIKENMDLQLDWCKEAPFYTLGPLTTDIAPGYDHITSGIGAAMIGWFGTAMLCYVTPKEHLGLPNKDDVKEGIITYKLAAHAADLAKGHPGAQVRDNALSKARFEFRWQDQFNLGLDPDKAREFHDETLPKDSAKVAHFCSMCGPHFCSMKITQDVREFAAQQGVSENDALKKGMEVKAVEFVKSGSEIYHRQ
>NC_006348.1|WP_004193339.1|3183028_3183334_-|pentapeptide-MXKDX-repeat-protein
MKRNLIAFACVAGFALAAPFAHAQNDAMSKDGMGMSKDAMSKGAMSGDAMSKDAMSKDAMSKDRMGKRHDHMAKGGMKAGPMSKDAMKEPMSSDKMSPMSN
>NC_006348.1|WP_004195184.1|3182043_3182868_-|DUF1223-domain-containing-protein
MSTDMSISFSVSLRAVAAALSLAAAGAAQAAADGACMARSPDGRQALVELYTSEGCSSCPPADDWLARLAARRAALRVVPLALHVDYWDGLGWADRFAQHRFTERQHALAARGGGRFVYTPEVAVDGRELRDWRDADAFGRRVVATAAEPARVGIALAAKRRAGALDVALSVTPRVGAPRALDAYLALYENGVESQVRAGENRGATLRHERVVRQWIGPLAATADAHASLDVRRALPLPANLRAADAARYGVAAFVEDPATGDVLQALDLPLCG
>NC_006348.1|WP_004195181.1|3180916_3182053_-|cytochrome-b/b6-domain-containing-protein
MRLNDARAIDQRTRVSPMSATPTTSASTTAMAGARASGAADAPARAPTGADIDAGATAWAEANANATANATTDPTIDATADATTDAMANVTTDAATRVTANPPIHETANVPASTAAAATTEAVAGARAGAALDAAHPGATQTMSQTMAQTMAQTMTQAGTEAASPAGTDAAASGACITRATRARRPIHPLWVRASHWLNALAAVTMALSGWRIYNASPIYAGFVFPRGATLGGWLGGALQWHFAAMWLLFFNGVFYLTMGVATGRFTRKLLPLSASGVARDLRDALRGRLSHDDLSVYNALQRAAYVAAIADLALLVLSGLVIWKSVQFPLLREWLGGYDRARVVHFWAMAFLVAFFVVHVAMAALVPRSLLAMLRGH
>NC_006348.1|WP_004195180.1|3180109_3180901_-|molybdopterin-dependent-oxidoreductase
MSENDRKKRENDIARIDRASLLIDVRKSLALPSRRLFGKRMLTLGGLAMLTGCTLRDDASVDDFLEKVSRANDRVQAWLFGPTRLAPTYAKADITRPFPFNAFYGIDDVPRVDADGFRLAVSGLVTGQRSWSLPALYALPHAEQITRHICVEGWSAIGRWGGTPFREFLRRVGADTSAKYVGFKCADDYYESIDMATALHPQTLLAFEYDGKRLPPEYGFPMKLRMPTKLGYKNPKHIVEIFVTNAYPGGYWVDQGYNWFGGS
>NC_006348.1|WP_004192284.1|3178720_3179656_-|EamA-family-transporter
MTPFDRFLAFVARHPPRLPQSRSGRVALALVFIYFAWGSTYLALHVALESFPPLLLSGLRNLLAGVGLFVFAMRRRPVRPTLVEIRNAALVGTMLVTMSSGLIALGMRTVSSGSAAVMVATVPLFATVIASVAGRRVTGGEWGAVALGMVGIVVLNSGGPSSPGSTLGSITVLAGALFWAGGAHLAARLALPHDLFLSTALQIGLGGAASTCIAWVLGERIGHVAWVPGAAFVYLMLAGTMAAYVAYGYLIRHTSPIIASSCMYVNPVVAVALGALLLGEPVTAATVIATIAILGSVGLSFVFDPARRRAQ
>NC_006348.1|WP_004193486.1|3177176_3178373_+|MFS-transporter
MSSQPRHSAGTPGHYSRSLLLLLATIAGVSVANIYYNQPLLDAFRASFPGSASWIGVVPTATQLGYATGMLVLAPLGDRFDRRTLILLQIAGLSAALVVAAAAPTLGVLAAASLAIGILATIAQQAVPFAAEIAPPAARGQAVGTVMSGLLLGILLARTAAGFVAEYFGWRAVFAASVAALAALAAVIVARLPRSSPTSTLPYGKLLASMWQLVRELRGLREASMTGGAIFAAFSAFWPVLTLLLAGAPFHLGPQAAGLFGIVGAAGALAAPYAGRFADKRGPRAIISLAIALIAASFAIFALSGASLIGLVIGVIVLDVGVQAAQISNQSRIYALKPDARSRVNTVFMVCYFIGGAIGSSAGVAAWRATGWLGMCAVGLLFSIVAAIVHFRGGAGAR
>NC_006348.1|WP_004192698.1|3176109_3176862_-|membrane-protein
MLNKVPEVTLAFWIVKIMSTTVGETGADYLAVHVGLGAAVTGALTACLLVGALALQWRARAYVPWIYWLNIVLVSVAGTQITDALTDGLGVSLHVSTPLFAAALAATFALWYRSERTLSIHTIVTPRREGFYWAAILLTFALGTAAGDLATEALGLGFRLGIVAFGGAIALVAAAALGGMNRVLAFWLAYILTRPLGASLGDFLSQAQAYGGLGLGTIRTSAVFLAVIVALVAGLSVAAARAGRLGARGR
>NC_006348.1|WP_004193824.1|3175567_3175978_-|hypothetical-protein
MIKRKLIAFAAAPALALAAFGIGTVSPAGVAPSMAEAATVSKLGDLSPFRAIAVDVAQRVDKGDLAGAKARIKDLETSWDDAEPSLKPRAAADWHAVDHAIDRALTALRADRPQAGACRQALADLLAVIDRPGGAR
>NC_006348.1|WP_004195190.1|3188364_3189552_-|MFS-transporter
MSNPSATSTRMSAPELRATTSLAAIFALRMLGLFMIMPVFSVYAKTIPGGENVVLVGIALGAYGVTQSLLYIFYGWASDKFGRKPVIAAGLLIFALGSFVAAFAHDITWIIVGRVIQGMGAVSSAVLAFIADLTSEHNRTKAMAMVGGSIGMSFAVAIVGAPIVFHWVGMSGLFAIVGALSVAAIGVVLWVVPDAPRPVHVPAPFAEVLHNVELLRLNFGVLVLHATQTALFLVVPRLLVDGGLPVASHWQVYLPVMGLAFVMMVPAIIVAEKQGRMKPVLLGGIAAILIGQLLLGVATHTILIVAAILFVYFLGFNILEASQPSLVSKLAPGSRKGAATGVYNTTQSIGLALGGVVGGVLLKHGGPDTVFFACSALVAVWLIIAAGMKQPPRKA
>NC_006348.1|WP_004195192.1|3189765_3192633_+|excinuclease-ABC-subunit-UvrA
MEQIRIRGARTHNLKNVNLDLPRHKLIVITGLSGSGKSSLAFDTLYAEGQRRYVESLSAYARQFLQLMEKPDVDLIEGLSPAISIEQKATSHNPRSTVGTVTEIHDYLRLLYARVGTPYCPDHEIPLEAQSVSQMVDAALALPEETRLMILAPVVANRKGEHAELFDEMQAQGFVRFRVRSGGGAANEGAAKIYEVDSLPKLKKNDKHTIDVVVDRLKVRPDMKQRLAESFETALRLADGRAIALEMDTDREHLFSSKFACPICSYSLQELEPRLFSFNNPMGACPECDGLGQITFFDPKRVVAHPSLSLAAGAVKGWDRRNQFYFQMLQSLAAFYDFDIDTAFEDLPEKIRKILLYGSGKQTILFSYINERGRTTIREHVFEGIIPNLERRYRETDSAAVREELAKYQNNQPCPSCDGTRLRREARFVRVGQGDYARAIFEVSSWPLRDALGYFDGLTLDGAKREIADKVIKEIVARLTFLNNVGLDYLSLERSAETLSGGEAQRIRLASQIGSGLTGVMYVLDEPSIGLHQRDNDRLIGTLKHLRDLGNSVIVVEHDEDMIRTADYVVDMGPGAGEHGGMIVAEGTPKQVQANGDSLTGQYLVGKRTIEYPDERISPDPQRMLRIVDAHGNNLKHVDLDLPVGLLTCITGVSGSGKSTLINDTLYNAVARHLYGSATEPAPHESIEGLEHFDKVINVDQSPIGRTPRSNPATYTGLFTPIRELFAGVPASKERGYDPGRFSFNVKGGRCESCQGDGVLKVEMHFLPDVYVPCDVCHGKRYNRETLEVQYKGRNISEVLDMTVEHAYEFFSAVPVVARKLKTLLDVGLGYIRLGQSATTLSGGEAQRVKLSLELSKRDTGRTLYILDEPTTGLHFHDIALLLEVIHRLRDQGNTVVIIEHNLDVIKTADWVIDLGPEGGAGGGQIIAQGTPEQVAKTKASFTGKYLAPLLKRKK
>NC_006348.1|WP_004195195.1|3192851_3193937_+|membrane-protein
MEKQSEPTREPQAREPHLRSVRLTSDFSLPKLSAIEIGSYLLALFGLWLVLRLKLLGGLLAGLLVYQLVHMIAPAIERHMSSQRARWVAVVLLSTAIVGGLAGLTIAVIEHFEHTVPNAQNLLGQVMQIVDQARTRTPEWISNLLPVDAEQMRAKAAGLMNRHMDQLQQGGKSVARGFGHVLFGMIIGAMIAIGIDRHKLRQPLSTALVARISRFSDAFRRIVFAQIKISALNAFFTAIYLLVALPIFHQRLPLSKTLVLVTFIAGLLPVVGNLISNTLIVAVSLSVSMGTAIASLVFLVVIHKLEYFLNAKIIGGQIESRAWELLLAMLVMEAAFGVPGVIAAPIFYAYVKRELIYLRLI
>NC_006348.1|WP_004195197.1|3194232_3195114_-|formyltetrahydrofolate-deformylase
MPADHSFILKLSCPDRRGIVHAVSGFLLERGSNILDSAQFGDSRTGEFFMRVHFEQAGACGAAAALDALRAEFAPLAEAFAMRWELHDAAVKPRVVILVSKIGHCLNDLLFRYHTGQLPIEISAIVSNHKDFYQLAASYDIPFHHLPLAAGASADAKAAQEARVLEVIDGHAADLVVLARYMQILSPALCERLAGRAINIHHSFLPSFKGAKPYYQAFDRGVKLIGATAHYVTTDLDEGPIIEQEVERVDHSMTPDELTAVGRDVECVTLARAVKWHVEHRIVLNGTKTVVFR
>NC_006348.1|WP_004195199.1|3195165_3196023_-|DUF4743-domain-containing-protein
MTFACIAAARRFDAAAHVPFAIAGRQVGWLRRGDVARLARWPDVFEFPAGRVELAARYDSVDARSMALASPIGALAAEGAIVGWRDEIYAIRNRFDDPPLAYIERAASRFFGTMTYAVHLNGIVEYAPSAPLAMWLGRRSATKATDPGMLDNVVAGGIGWGLGIEDTIAKECWEEAGIAAELAARAIPGRVAHVLRSLPEGTQAEQIFVYDLPLPRDFVPHNQDGEVAEHLLAGVDEIVAWLRAGEATVDASLAMLDSLLRHRAIAPEDARGIDVLFAPPPLGLG
>NC_006348.1|WP_004195200.1|3196035_3196620_-|LysE-family-translocator
MPNFMLFLATSIAITVAPGPDNLQVLARGISQGRAAGIVAALGFASGVLFHTTLAAFGVAALLRSSPVAFHLLKLAGGAYLIWIGIKALRSKGLATAHARAPQPLSTIFRQSVIGNLLNPKVTLFFVVFLPQFVDPHGAQPVALQMLELGALFMAQTAAVFSVFGVGAGAIGVWLDRLAGATFVALGLRVALKD
>NC_006348.1|WP_004195204.1|3197359_3199369_-|potassium-efflux-system-protein
MISPLEMTLLLLLASVVGVVVFRSLNLPPMLGYLTVGILVGPHALGFAADLERAEHLAEFGVVFLMFSIGLEFSLSKLRAMRRLVFGLGLAQVLGTIAIALVLGALFERWMHITWEGSVALGGALAMSSTAIVSKMLAERLEIETEHGRNIFGVLLFQDLAVVPLLIVIAAFGGESSKDLAMSLGFAAVKIVVALALLLIVGQRFMTRWLNVVARRRSQELFVLNLLLVTLGAAFITDRFGLSLALGAFIAGMLISETPYRHQVEEDIKPFRDVLLGLFFVTTGMLLDPSVIWRHPLLVLAFFVGQVLLKSVMITGLARAFGATPGVAMRTGLGLAQAGEFGFVLLNLILDRHLVDATLLQSILASMLLSMLAAPFLIQNADRIVMRLSAAEWMQQSLQMTRIATQSIKQKGHVIICGYGRAGQNLARMLEQEGIAYVALDLDPDRVAAAAAAGESVVFGDAARRESLLAAGIHRAAAVAVTYANTPSALRVLHNVHELEPTLPAIVRTVDDADLEKLLAAGATEVIPEIVEGSLMLASHTLVLMGVPMRRVVRRVEEMRDARYSLLRGYFHGADDADDDDHEQVRLQSVPVDARADAVGRSLSELGLFALGLEVTAIRRHGIRGVEPDPETKLRASDIVVLRGLPEALAQAEERLSRHRREGGSAAVA
>NC_006348.1|WP_004195206.1|3199496_3200480_+|KpsF/GutQ-family-sugar-phosphate-isomerase
MIAKINDDRALALARDVLDIEANAVRALAEQLDGEFVAAVGLLLNCRGRVVVSGIGKSGHIARKIAATLASTGTPAFFVHPAEASHGDLGMVTKDDVFVAISNSGESEELVAILPLIKRLGAKLIAMTGRPASSLATLSDVHLNAGVAKEACPLNLAPTASTTAALALGDALAVAVLDARGFGSDDFARSHPGGALGRRLLTYVRDVMRTGDEVPAVPLDATLSDALFQITAKRMGMTAVIDDANRVAGIFTDGDLRRVLERDGDFRRLPIVDVMTRHPRTIAPDHLAVEAVELMERHRINQMLVVDERGALIGALNMHDLFSKKVI
>NC_006348.1|WP_004200146.1|3200479_3201019_+|HAD-family-hydrolase
MSAPPATAAERASRVKLMIFDVDGVLTDGGLHFTAAGDAMKSFNTLDGHGVKLLGEAGIATAIITGRRSEALAARAKEMRIAHLHEGVENKLAVFGELLRALGLEPGECGYMGDDWPDLAVMLRCGFAAAPANAHPDVIARAHWVAEARGGHGAVREVCDAILRAQHRYDALLAAACGA
>NC_006348.1|WP_004195210.1|3201024_3201639_+|LPS-export-ABC-transporter-periplasmic-protein-LptC
MDGKFRLTSMIPLAAMAALAGGTYWLLQATLPPPGEAVVRPKSHTPDYFADNFSVTELDQTGSTQYRLTAAGLVHYEDDETSNLTRPALRAFQPGKPTVTATAKRGAVNGDVSIVDLYDDARILRAAGAGDPPMQADSQHFRVLVNDDVIETEKPVKLQRGLSIANAAAGMKYNNVTRVIELYGNVRGTIAASDTSGGAAGQPK

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NC_006348_1	1.1\|3187757\|35\|NC_006348\|PILER-CR	3187757-3187791	35	NZ_CP044425	Paracoccus pantotrophus strain DSM 2944 plasmid pPAN2, complete sequence	201582-201616	8	0.771
NC_006348_1	1.1\|3187757\|35\|NC_006348\|PILER-CR	3187757-3187791	35	NC_016113	Streptomyces cattleya NRRL 8057 = DSM 46488 plasmid pSCAT, complete sequence	1175859-1175893	8	0.771
NC_006348_1	1.1\|3187757\|35\|NC_006348\|PILER-CR	3187757-3187791	35	NC_017585	Streptomyces cattleya NRRL 8057 = DSM 46488 plasmid pSCATT, complete sequence	637671-637705	8	0.771
NC_006348_1	1.1\|3187757\|35\|NC_006348\|PILER-CR	3187757-3187791	35	NC_017958	Tistrella mobilis KA081020-065 plasmid pTM3, complete sequence	384572-384606	9	0.743
NC_006348_1	1.1\|3187757\|35\|NC_006348\|PILER-CR	3187757-3187791	35	NC_014642	Achromobacter xylosoxidans A8 plasmid pA82, complete sequence	132283-132317	10	0.714
NC_006348_1	1.1\|3187757\|35\|NC_006348\|PILER-CR	3187757-3187791	35	NZ_CP016613	Ralstonia solanacearum FJAT-91 plasmid unnamed1, complete sequence	1540873-1540907	11	0.686
NC_006348_1	1.1\|3187757\|35\|NC_006348\|PILER-CR	3187757-3187791	35	NZ_CP049790	Ralstonia solanacearum strain 202 plasmid unnamed, complete sequence	966155-966189	11	0.686
NC_006348_1	1.1\|3187757\|35\|NC_006348\|PILER-CR	3187757-3187791	35	NZ_CP039340	Ralstonia solanacearum strain UW386 plasmid pUW386, complete sequence	1769139-1769173	11	0.686
NC_006348_1	1.1\|3187757\|35\|NC_006348\|PILER-CR	3187757-3187791	35	NZ_CP016555	Ralstonia solanacearum FJAT-1458 plasmid plas1, complete sequence	723991-724025	11	0.686
NC_006348_1	1.1\|3187757\|35\|NC_006348\|PILER-CR	3187757-3187791	35	NZ_CP016915	Ralstonia solanacearum strain CQPS-1 plasmid unnamed, complete sequence	1561644-1561678	11	0.686
NC_006348_1	1.1\|3187757\|35\|NC_006348\|PILER-CR	3187757-3187791	35	NZ_CP052071	Ralstonia solanacearum strain FJAT454.F1 plasmid Plas1, complete sequence	1085915-1085949	11	0.686
NC_006348_1	1.1\|3187757\|35\|NC_006348\|PILER-CR	3187757-3187791	35	NZ_CP022482	Ralstonia solanacearum strain HA4-1 plasmid HA4-1MP, complete sequence	1935088-1935122	11	0.686
NC_006348_1	1.1\|3187757\|35\|NC_006348\|PILER-CR	3187757-3187791	35	CP023015	Ralstonia solanacearum strain T25 plasmid unnamed, complete sequence	899468-899502	11	0.686
NC_006348_1	1.1\|3187757\|35\|NC_006348\|PILER-CR	3187757-3187791	35	NZ_CP052075	Ralstonia solanacearum strain FJAT448.F1 plasmid Plas1, complete sequence	1085882-1085916	11	0.686
NC_006348_1	1.1\|3187757\|35\|NC_006348\|PILER-CR	3187757-3187791	35	NZ_CP052105	Ralstonia solanacearum strain FJAT15252.F1 plasmid Plas1, complete sequence	1085883-1085917	11	0.686
NC_006348_1	1.1\|3187757\|35\|NC_006348\|PILER-CR	3187757-3187791	35	NZ_CP052115	Ralstonia solanacearum strain FJAT1463.F50 plasmid Plas1, complete sequence	1085896-1085930	11	0.686
NC_006348_1	1.1\|3187757\|35\|NC_006348\|PILER-CR	3187757-3187791	35	NZ_CP052107	Ralstonia solanacearum strain FJAT15249.F50 plasmid Plas1, complete sequence	1085896-1085930	11	0.686
NC_006348_1	1.1\|3187757\|35\|NC_006348\|PILER-CR	3187757-3187791	35	NZ_CP022781	Ralstonia solanacearum strain SL3822 plasmid unnamed, complete sequence	878649-878683	11	0.686
NC_006348_1	1.1\|3187757\|35\|NC_006348\|PILER-CR	3187757-3187791	35	NZ_CP052117	Ralstonia solanacearum strain FJAT1463.F1 plasmid Plas1, complete sequence	1085885-1085919	11	0.686
NC_006348_1	1.1\|3187757\|35\|NC_006348\|PILER-CR	3187757-3187791	35	NZ_CP052129	Ralstonia solanacearum strain FJAT1303.F1 plasmid Plas1, complete sequence	1009574-1009608	11	0.686
NC_006348_1	1.1\|3187757\|35\|NC_006348\|PILER-CR	3187757-3187791	35	NZ_CP052121	Ralstonia solanacearum strain FJAT1458.F1 plasmid Plas1, complete sequence	1085885-1085919	11	0.686
NC_006348_1	1.1\|3187757\|35\|NC_006348\|PILER-CR	3187757-3187791	35	NZ_CP052073	Ralstonia solanacearum strain FJAT448.F50 plasmid Plas1, complete sequence	1085881-1085915	11	0.686
NC_006348_1	1.1\|3187757\|35\|NC_006348\|PILER-CR	3187757-3187791	35	NZ_CP052109	Ralstonia solanacearum strain FJAT15249.F1 plasmid Plas1, complete sequence	1085896-1085930	11	0.686
NC_006348_1	1.1\|3187757\|35\|NC_006348\|PILER-CR	3187757-3187791	35	NZ_CP052111	Ralstonia solanacearum strain FJAT15244.F50 plasmid Plas1, complete sequence	869414-869448	11	0.686
NC_006348_1	1.1\|3187757\|35\|NC_006348\|PILER-CR	3187757-3187791	35	NZ_CP052103	Ralstonia solanacearum strain FJAT15252.F50 plasmid Plas1, complete sequence	1085907-1085941	11	0.686
NC_006348_1	1.1\|3187757\|35\|NC_006348\|PILER-CR	3187757-3187791	35	NZ_CP052119	Ralstonia solanacearum strain FJAT1458.F50 plasmid Plas1, complete sequence	1085885-1085919	11	0.686
NC_006348_1	1.1\|3187757\|35\|NC_006348\|PILER-CR	3187757-3187791	35	NZ_CP052113	Ralstonia solanacearum strain FJAT15244.F1 plasmid Plas1, complete sequence	869414-869448	11	0.686
NC_006348_1	1.1\|3187757\|35\|NC_006348\|PILER-CR	3187757-3187791	35	CP023013	Ralstonia solanacearum strain T110 plasmid unnamed, complete sequence	1087535-1087569	11	0.686
NC_006348_1	1.1\|3187757\|35\|NC_006348\|PILER-CR	3187757-3187791	35	NZ_CP049794	Ralstonia solanacearum strain 204 plasmid unnamed, complete sequence	1705689-1705723	11	0.686
NC_006348_1	1.1\|3187757\|35\|NC_006348\|PILER-CR	3187757-3187791	35	NZ_CP049788	Ralstonia solanacearum strain B2 plasmid unnamed, complete sequence	1013933-1013967	11	0.686
NC_006348_1	1.1\|3187757\|35\|NC_006348\|PILER-CR	3187757-3187791	35	NZ_CP022766	Ralstonia solanacearum strain T78 plasmid unnamed, complete sequence	1157590-1157624	11	0.686
NC_006348_1	1.1\|3187757\|35\|NC_006348\|PILER-CR	3187757-3187791	35	NZ_CP021763	Ralstonia pseudosolanacearum strain RS 476 plasmid unnamed, complete sequence	1172508-1172542	11	0.686
NC_006348_1	1.1\|3187757\|35\|NC_006348\|PILER-CR	3187757-3187791	35	NZ_CP015116	Ralstonia solanacearum strain EP1 plasmid unnamed, complete sequence	1345003-1345037	11	0.686
NC_006348_1	1.1\|3187757\|35\|NC_006348\|PILER-CR	3187757-3187791	35	NZ_CP049792	Ralstonia solanacearum strain 203 plasmid unnamed, complete sequence	1480850-1480884	11	0.686
NC_006348_1	1.1\|3187757\|35\|NC_006348\|PILER-CR	3187757-3187791	35	NZ_CP052069	Ralstonia solanacearum strain FJAT91.F50 plasmid Plas1, complete sequence	1090037-1090071	11	0.686
NC_006348_1	1.1\|3187757\|35\|NC_006348\|PILER-CR	3187757-3187791	35	NZ_CP025986	Ralstonia solanacearum strain RSCM plasmid p-unname2, complete sequence	1394784-1394818	11	0.686
NC_006348_1	1.1\|3187757\|35\|NC_006348\|PILER-CR	3187757-3187791	35	NZ_CP022769	Ralstonia solanacearum strain T60 plasmid unnamed, complete sequence	1165341-1165375	11	0.686
NC_006348_1	1.1\|3187757\|35\|NC_006348\|PILER-CR	3187757-3187791	35	NZ_CP015851	Ralstonia solanacearum strain YC40-M plasmid, complete sequence	1274303-1274337	11	0.686
NC_006348_1	1.1\|3187757\|35\|NC_006348\|PILER-CR	3187757-3187791	35	NZ_CP022773	Ralstonia solanacearum strain T42 plasmid unnamed, complete sequence	880196-880230	11	0.686
NC_006348_1	1.1\|3187757\|35\|NC_006348\|PILER-CR	3187757-3187791	35	NZ_CP022783	Ralstonia solanacearum strain SL3755 plasmid unnamed, complete sequence	1093219-1093253	11	0.686
NC_006348_1	1.1\|3187757\|35\|NC_006348\|PILER-CR	3187757-3187791	35	NZ_CP022795	Ralstonia solanacearum strain SL2330 plasmid unnamed, complete sequence	1089923-1089957	11	0.686
NC_006348_1	1.1\|3187757\|35\|NC_006348\|PILER-CR	3187757-3187791	35	NZ_CP009763	Ralstonia solanacearum OE1-1 plasmid unnamed, complete sequence	1060780-1060814	11	0.686
NC_006348_1	1.1\|3187757\|35\|NC_006348\|PILER-CR	3187757-3187791	35	NZ_CP022779	Ralstonia solanacearum strain SL3882 plasmid unnamed, complete sequence	1165330-1165364	11	0.686
NC_006348_1	1.1\|3187757\|35\|NC_006348\|PILER-CR	3187757-3187791	35	NZ_CP052085	Ralstonia solanacearum strain FJAT15353.F8 plasmid Plas1, complete sequence	1147977-1148011	11	0.686
NC_006348_1	1.1\|3187757\|35\|NC_006348\|PILER-CR	3187757-3187791	35	NZ_CP052095	Ralstonia solanacearum strain FJAT15340.F1 plasmid Plas1, complete sequence	1175583-1175617	11	0.686
NC_006348_1	1.1\|3187757\|35\|NC_006348\|PILER-CR	3187757-3187791	35	NZ_CP052077	Ralstonia solanacearum strain FJAT445.F50 plasmid Plas1, complete sequence	1069493-1069527	11	0.686
NC_006348_1	1.1\|3187757\|35\|NC_006348\|PILER-CR	3187757-3187791	35	NZ_CP052087	Ralstonia solanacearum strain FJAT15353.F50 plasmid Plas1, complete sequence	1147977-1148011	11	0.686
NC_006348_1	1.1\|3187757\|35\|NC_006348\|PILER-CR	3187757-3187791	35	NZ_CP052097	Ralstonia solanacearum strain FJAT15304.F6 plasmid Plas1, complete sequence	1175583-1175617	11	0.686
NC_006348_1	1.1\|3187757\|35\|NC_006348\|PILER-CR	3187757-3187791	35	NZ_CP052127	Ralstonia solanacearum strain FJAT1303.F50 plasmid Plas1, complete sequence	1147977-1148011	11	0.686
NC_006348_1	1.1\|3187757\|35\|NC_006348\|PILER-CR	3187757-3187791	35	NZ_CP052079	Ralstonia solanacearum strain FJAT445.F1 plasmid Plas1, complete sequence	1069516-1069550	11	0.686
NC_006348_1	1.1\|3187757\|35\|NC_006348\|PILER-CR	3187757-3187791	35	NZ_CP052089	Ralstonia solanacearum strain FJAT15353.F1 plasmid Plas1, complete sequence	1147981-1148015	11	0.686
NC_006348_1	1.1\|3187757\|35\|NC_006348\|PILER-CR	3187757-3187791	35	NZ_CP052093	Ralstonia solanacearum strain FJAT15340.F50 plasmid Plas1, complete sequence	1175583-1175617	11	0.686
NC_006348_1	1.1\|3187757\|35\|NC_006348\|PILER-CR	3187757-3187791	35	NZ_CP052101	Ralstonia solanacearum strain FJAT15304.F1 plasmid Plas1, complete sequence	1175583-1175617	11	0.686
NC_006348_1	1.1\|3187757\|35\|NC_006348\|PILER-CR	3187757-3187791	35	NZ_CP052099	Ralstonia solanacearum strain FJAT15304.F50 plasmid Plas1, complete sequence	1175583-1175617	11	0.686
NC_006348_1	1.1\|3187757\|35\|NC_006348\|PILER-CR	3187757-3187791	35	NZ_CP052125	Ralstonia solanacearum strain FJAT1452.F1 plasmid Plas1, complete sequence	1069516-1069550	11	0.686
NC_006348_1	1.1\|3187757\|35\|NC_006348\|PILER-CR	3187757-3187791	35	NZ_CP022793	Ralstonia solanacearum strain SL2729 plasmid unnamed, complete sequence	1088133-1088167	11	0.686
NC_006348_1	1.1\|3187757\|35\|NC_006348\|PILER-CR	3187757-3187791	35	NZ_CP022785	Ralstonia solanacearum strain SL3730 plasmid unnamed, complete sequence	1068802-1068836	11	0.686
NC_006348_1	1.1\|3187757\|35\|NC_006348\|PILER-CR	3187757-3187791	35	NZ_CP022787	Ralstonia solanacearum strain SL3300 plasmid unnamed, complete sequence	1116466-1116500	11	0.686
NC_006348_1	1.1\|3187757\|35\|NC_006348\|PILER-CR	3187757-3187791	35	NZ_CP022756	Ralstonia solanacearum strain T117 plasmid unnamed, complete sequence	1162910-1162944	11	0.686
NC_006348_1	1.1\|3187757\|35\|NC_006348\|PILER-CR	3187757-3187791	35	NZ_CP052123	Ralstonia solanacearum strain FJAT1452.F50 plasmid Plas1, complete sequence	1069516-1069550	11	0.686
NC_006348_1	1.1\|3187757\|35\|NC_006348\|PILER-CR	3187757-3187791	35	NZ_CP052131	Ralstonia solanacearum strain FJAT1303.F8 plasmid Plas1, complete sequence	1147976-1148010	11	0.686
NC_006348_1	1.1\|3187757\|35\|NC_006348\|PILER-CR	3187757-3187791	35	NZ_CP052081	Ralstonia solanacearum strain FJAT442.F50 plasmid Plas1, complete sequence	1069516-1069550	11	0.686
NC_006348_1	1.1\|3187757\|35\|NC_006348\|PILER-CR	3187757-3187791	35	NZ_CP052083	Ralstonia solanacearum strain FJAT442.F1 plasmid Plas1, complete sequence	1069516-1069550	11	0.686
NC_006348_1	1.1\|3187757\|35\|NC_006348\|PILER-CR	3187757-3187791	35	NZ_CP052091	Ralstonia solanacearum strain FJAT15340.F6 plasmid Plas1, complete sequence	1175584-1175618	11	0.686

1. spacer 1.1|3187757|35|NC_006348|PILER-CR matches to NZ_CP044425 (Paracoccus pantotrophus strain DSM 2944 plasmid pPAN2, complete sequence) position: , mismatch: 8, identity: 0.771

gccgctgcgcgcacccgcgccgccgccacccgacg	CRISPR spacer
ggcgacgcgcgcgcccgcgccaccgccacccgcgc	Protospacer
* ** .******.********.**********

2. spacer 1.1|3187757|35|NC_006348|PILER-CR matches to NC_016113 (Streptomyces cattleya NRRL 8057 = DSM 46488 plasmid pSCAT, complete sequence) position: , mismatch: 8, identity: 0.771

gccgctgcgcgcacccgcgccgccgcc----acccgacg	CRISPR spacer
ggcgctgcgcgccgccgcgccgccgcccggggccc----	Protospacer
* **********  *************    .***

3. spacer 1.1|3187757|35|NC_006348|PILER-CR matches to NC_017585 (Streptomyces cattleya NRRL 8057 = DSM 46488 plasmid pSCATT, complete sequence) position: , mismatch: 8, identity: 0.771

gccgctgcgcgcacccgcgccgccgcc----acccgacg	CRISPR spacer
ggcgctgcgcgccgccgcgccgccgcccggggccc----	Protospacer
* **********  *************    .***

4. spacer 1.1|3187757|35|NC_006348|PILER-CR matches to NC_017958 (Tistrella mobilis KA081020-065 plasmid pTM3, complete sequence) position: , mismatch: 9, identity: 0.743

gccgctgcgcgcacccgcgccgccgccacccgacg	CRISPR spacer
gtcgatgcgcgcaccctcgccgccgccatggggtt	Protospacer
*.** *********** ***********.  *..

5. spacer 1.1|3187757|35|NC_006348|PILER-CR matches to NC_014642 (Achromobacter xylosoxidans A8 plasmid pA82, complete sequence) position: , mismatch: 10, identity: 0.714

gccgctgcgcgcacccgcgccgccgccacccgacg	CRISPR spacer
accctcctgcgcacccgcgacgccgccaccggagc	Protospacer
.** .. .*********** ********** **

6. spacer 1.1|3187757|35|NC_006348|PILER-CR matches to NZ_CP016613 (Ralstonia solanacearum FJAT-91 plasmid unnamed1, complete sequence) position: , mismatch: 11, identity: 0.686

gccgctgcgcgcacccgcgccgccgccacccgacg	CRISPR spacer
agcgcgtcgcgcacccgcgccgccgcctgttcggg	Protospacer
. ***  ********************  .. . *

7. spacer 1.1|3187757|35|NC_006348|PILER-CR matches to NZ_CP049790 (Ralstonia solanacearum strain 202 plasmid unnamed, complete sequence) position: , mismatch: 11, identity: 0.686

gccgctgcgcgcacccgcgccgccgccacccgacg	CRISPR spacer
agcgcgtcgcgcacccgcgccgccgcctgttcggg	Protospacer
. ***  ********************  .. . *

8. spacer 1.1|3187757|35|NC_006348|PILER-CR matches to NZ_CP039340 (Ralstonia solanacearum strain UW386 plasmid pUW386, complete sequence) position: , mismatch: 11, identity: 0.686

gccgctgcgcgcacccgcgccgccgccacccgacg	CRISPR spacer
aacgcatcgcgcacccgcgccgccgcctgttcggg	Protospacer
. ***  ********************  .. . *

9. spacer 1.1|3187757|35|NC_006348|PILER-CR matches to NZ_CP016555 (Ralstonia solanacearum FJAT-1458 plasmid plas1, complete sequence) position: , mismatch: 11, identity: 0.686

gccgctgcgcgcacccgcgccgccgccacccgacg	CRISPR spacer
agcgcgtcgcgcacccgcgccgccgcctgttcggg	Protospacer
. ***  ********************  .. . *

10. spacer 1.1|3187757|35|NC_006348|PILER-CR matches to NZ_CP016915 (Ralstonia solanacearum strain CQPS-1 plasmid unnamed, complete sequence) position: , mismatch: 11, identity: 0.686

gccgctgcgcgcacccgcgccgccgccacccgacg	CRISPR spacer
agcgcgtcgcgcacccgcgccgccgcctgttcggg	Protospacer
. ***  ********************  .. . *

11. spacer 1.1|3187757|35|NC_006348|PILER-CR matches to NZ_CP052071 (Ralstonia solanacearum strain FJAT454.F1 plasmid Plas1, complete sequence) position: , mismatch: 11, identity: 0.686

gccgctgcgcgcacccgcgccgccgccacccgacg	CRISPR spacer
agcgcgtcgcgcacccgcgccgccgcctgttcggg	Protospacer
. ***  ********************  .. . *

12. spacer 1.1|3187757|35|NC_006348|PILER-CR matches to NZ_CP022482 (Ralstonia solanacearum strain HA4-1 plasmid HA4-1MP, complete sequence) position: , mismatch: 11, identity: 0.686

gccgctgcgcgcacccgcgccgccgccacccgacg	CRISPR spacer
agcgcgtcgcgcacccgcgccgccgcctgttcggg	Protospacer
. ***  ********************  .. . *

13. spacer 1.1|3187757|35|NC_006348|PILER-CR matches to CP023015 (Ralstonia solanacearum strain T25 plasmid unnamed, complete sequence) position: , mismatch: 11, identity: 0.686

gccgctgcgcgcacccgcgccgccgccacccgacg	CRISPR spacer
agcgcgtcgcgcacccgcgccgccgcctgttcggg	Protospacer
. ***  ********************  .. . *

14. spacer 1.1|3187757|35|NC_006348|PILER-CR matches to NZ_CP052075 (Ralstonia solanacearum strain FJAT448.F1 plasmid Plas1, complete sequence) position: , mismatch: 11, identity: 0.686

gccgctgcgcgcacccgcgccgccgccacccgacg	CRISPR spacer
agcgcgtcgcgcacccgcgccgccgcctgttcggg	Protospacer
. ***  ********************  .. . *

15. spacer 1.1|3187757|35|NC_006348|PILER-CR matches to NZ_CP052105 (Ralstonia solanacearum strain FJAT15252.F1 plasmid Plas1, complete sequence) position: , mismatch: 11, identity: 0.686

gccgctgcgcgcacccgcgccgccgccacccgacg	CRISPR spacer
agcgcgtcgcgcacccgcgccgccgcctgttcggg	Protospacer
. ***  ********************  .. . *

16. spacer 1.1|3187757|35|NC_006348|PILER-CR matches to NZ_CP052115 (Ralstonia solanacearum strain FJAT1463.F50 plasmid Plas1, complete sequence) position: , mismatch: 11, identity: 0.686

gccgctgcgcgcacccgcgccgccgccacccgacg	CRISPR spacer
agcgcgtcgcgcacccgcgccgccgcctgttcggg	Protospacer
. ***  ********************  .. . *

17. spacer 1.1|3187757|35|NC_006348|PILER-CR matches to NZ_CP052107 (Ralstonia solanacearum strain FJAT15249.F50 plasmid Plas1, complete sequence) position: , mismatch: 11, identity: 0.686

gccgctgcgcgcacccgcgccgccgccacccgacg	CRISPR spacer
agcgcgtcgcgcacccgcgccgccgcctgttcggg	Protospacer
. ***  ********************  .. . *

18. spacer 1.1|3187757|35|NC_006348|PILER-CR matches to NZ_CP022781 (Ralstonia solanacearum strain SL3822 plasmid unnamed, complete sequence) position: , mismatch: 11, identity: 0.686

gccgctgcgcgcacccgcgccgccgccacccgacg	CRISPR spacer
agcgcgtcgcgcacccgcgccgccgcctgttcggg	Protospacer
. ***  ********************  .. . *

19. spacer 1.1|3187757|35|NC_006348|PILER-CR matches to NZ_CP052117 (Ralstonia solanacearum strain FJAT1463.F1 plasmid Plas1, complete sequence) position: , mismatch: 11, identity: 0.686

gccgctgcgcgcacccgcgccgccgccacccgacg	CRISPR spacer
agcgcgtcgcgcacccgcgccgccgcctgttcggg	Protospacer
. ***  ********************  .. . *

20. spacer 1.1|3187757|35|NC_006348|PILER-CR matches to NZ_CP052129 (Ralstonia solanacearum strain FJAT1303.F1 plasmid Plas1, complete sequence) position: , mismatch: 11, identity: 0.686

gccgctgcgcgcacccgcgccgccgccacccgacg	CRISPR spacer
agcgcgtcgcgcacccgcgccgccgcctgttcggg	Protospacer
. ***  ********************  .. . *

21. spacer 1.1|3187757|35|NC_006348|PILER-CR matches to NZ_CP052121 (Ralstonia solanacearum strain FJAT1458.F1 plasmid Plas1, complete sequence) position: , mismatch: 11, identity: 0.686

gccgctgcgcgcacccgcgccgccgccacccgacg	CRISPR spacer
agcgcgtcgcgcacccgcgccgccgcctgttcggg	Protospacer
. ***  ********************  .. . *

22. spacer 1.1|3187757|35|NC_006348|PILER-CR matches to NZ_CP052073 (Ralstonia solanacearum strain FJAT448.F50 plasmid Plas1, complete sequence) position: , mismatch: 11, identity: 0.686

gccgctgcgcgcacccgcgccgccgccacccgacg	CRISPR spacer
agcgcgtcgcgcacccgcgccgccgcctgttcggg	Protospacer
. ***  ********************  .. . *

23. spacer 1.1|3187757|35|NC_006348|PILER-CR matches to NZ_CP052109 (Ralstonia solanacearum strain FJAT15249.F1 plasmid Plas1, complete sequence) position: , mismatch: 11, identity: 0.686

gccgctgcgcgcacccgcgccgccgccacccgacg	CRISPR spacer
agcgcgtcgcgcacccgcgccgccgcctgttcggg	Protospacer
. ***  ********************  .. . *

24. spacer 1.1|3187757|35|NC_006348|PILER-CR matches to NZ_CP052111 (Ralstonia solanacearum strain FJAT15244.F50 plasmid Plas1, complete sequence) position: , mismatch: 11, identity: 0.686

gccgctgcgcgcacccgcgccgccgccacccgacg	CRISPR spacer
agcgcgtcgcgcacccgcgccgccgcctgttcggg	Protospacer
. ***  ********************  .. . *

25. spacer 1.1|3187757|35|NC_006348|PILER-CR matches to NZ_CP052103 (Ralstonia solanacearum strain FJAT15252.F50 plasmid Plas1, complete sequence) position: , mismatch: 11, identity: 0.686

gccgctgcgcgcacccgcgccgccgccacccgacg	CRISPR spacer
agcgcgtcgcgcacccgcgccgccgcctgttcggg	Protospacer
. ***  ********************  .. . *

26. spacer 1.1|3187757|35|NC_006348|PILER-CR matches to NZ_CP052119 (Ralstonia solanacearum strain FJAT1458.F50 plasmid Plas1, complete sequence) position: , mismatch: 11, identity: 0.686

gccgctgcgcgcacccgcgccgccgccacccgacg	CRISPR spacer
agcgcgtcgcgcacccgcgccgccgcctgttcggg	Protospacer
. ***  ********************  .. . *

27. spacer 1.1|3187757|35|NC_006348|PILER-CR matches to NZ_CP052113 (Ralstonia solanacearum strain FJAT15244.F1 plasmid Plas1, complete sequence) position: , mismatch: 11, identity: 0.686

gccgctgcgcgcacccgcgccgccgccacccgacg	CRISPR spacer
agcgcgtcgcgcacccgcgccgccgcctgttcggg	Protospacer
. ***  ********************  .. . *

28. spacer 1.1|3187757|35|NC_006348|PILER-CR matches to CP023013 (Ralstonia solanacearum strain T110 plasmid unnamed, complete sequence) position: , mismatch: 11, identity: 0.686

gccgctgcgcgcacccgcgccgccgccacccgacg	CRISPR spacer
agcgcgtcgcgcacccgcgccgccgcctgttcggg	Protospacer
. ***  ********************  .. . *

29. spacer 1.1|3187757|35|NC_006348|PILER-CR matches to NZ_CP049794 (Ralstonia solanacearum strain 204 plasmid unnamed, complete sequence) position: , mismatch: 11, identity: 0.686

gccgctgcgcgcacccgcgccgccgccacccgacg	CRISPR spacer
agcgcgtcgcgcacccgcgccgccgcctgttcggg	Protospacer
. ***  ********************  .. . *

30. spacer 1.1|3187757|35|NC_006348|PILER-CR matches to NZ_CP049788 (Ralstonia solanacearum strain B2 plasmid unnamed, complete sequence) position: , mismatch: 11, identity: 0.686

gccgctgcgcgcacccgcgccgccgccacccgacg	CRISPR spacer
agcgcgtcgcgcacccgcgccgccgcctgttcggg	Protospacer
. ***  ********************  .. . *

31. spacer 1.1|3187757|35|NC_006348|PILER-CR matches to NZ_CP022766 (Ralstonia solanacearum strain T78 plasmid unnamed, complete sequence) position: , mismatch: 11, identity: 0.686

gccgctgcgcgcacccgcgccgccgccacccgacg	CRISPR spacer
agcgcgtcgcgcacccgcgccgccgcctgttcggg	Protospacer
. ***  ********************  .. . *

32. spacer 1.1|3187757|35|NC_006348|PILER-CR matches to NZ_CP021763 (Ralstonia pseudosolanacearum strain RS 476 plasmid unnamed, complete sequence) position: , mismatch: 11, identity: 0.686

gccgctgcgcgcacccgcgccgccgccacccgacg	CRISPR spacer
agcgcgtcgcgcacccgcgccgccgcctgttcggg	Protospacer
. ***  ********************  .. . *

33. spacer 1.1|3187757|35|NC_006348|PILER-CR matches to NZ_CP015116 (Ralstonia solanacearum strain EP1 plasmid unnamed, complete sequence) position: , mismatch: 11, identity: 0.686

gccgctgcgcgcacccgcgccgccgccacccgacg	CRISPR spacer
agcgcgtcgcgcacccgcgccgccgcctgttcggg	Protospacer
. ***  ********************  .. . *

34. spacer 1.1|3187757|35|NC_006348|PILER-CR matches to NZ_CP049792 (Ralstonia solanacearum strain 203 plasmid unnamed, complete sequence) position: , mismatch: 11, identity: 0.686

gccgctgcgcgcacccgcgccgccgccacccgacg	CRISPR spacer
agcgcgtcgcgcacccgcgccgccgcctgttcggg	Protospacer
. ***  ********************  .. . *

35. spacer 1.1|3187757|35|NC_006348|PILER-CR matches to NZ_CP052069 (Ralstonia solanacearum strain FJAT91.F50 plasmid Plas1, complete sequence) position: , mismatch: 11, identity: 0.686

gccgctgcgcgcacccgcgccgccgccacccgacg	CRISPR spacer
agcgcgtcgcgcacccgcgccgccgcctgttcggg	Protospacer
. ***  ********************  .. . *

36. spacer 1.1|3187757|35|NC_006348|PILER-CR matches to NZ_CP025986 (Ralstonia solanacearum strain RSCM plasmid p-unname2, complete sequence) position: , mismatch: 11, identity: 0.686

gccgctgcgcgcacccgcgccgccgccacccgacg	CRISPR spacer
agcgcgtcgcgcacccgcgccgccgcctgttcggg	Protospacer
. ***  ********************  .. . *

37. spacer 1.1|3187757|35|NC_006348|PILER-CR matches to NZ_CP022769 (Ralstonia solanacearum strain T60 plasmid unnamed, complete sequence) position: , mismatch: 11, identity: 0.686

gccgctgcgcgcacccgcgccgccgccacccgacg	CRISPR spacer
agcgcgtcgcgcacccgcgccgccgcctgttcggg	Protospacer
. ***  ********************  .. . *

38. spacer 1.1|3187757|35|NC_006348|PILER-CR matches to NZ_CP015851 (Ralstonia solanacearum strain YC40-M plasmid, complete sequence) position: , mismatch: 11, identity: 0.686

gccgctgcgcgcacccgcgccgccgccacccgacg	CRISPR spacer
agcgcgtcgcgcacccgcgccgccgcctgttcggg	Protospacer
. ***  ********************  .. . *

39. spacer 1.1|3187757|35|NC_006348|PILER-CR matches to NZ_CP022773 (Ralstonia solanacearum strain T42 plasmid unnamed, complete sequence) position: , mismatch: 11, identity: 0.686

gccgctgcgcgcacccgcgccgccgccacccgacg	CRISPR spacer
agcgcgtcgcgcacccgcgccgccgcctgttcggg	Protospacer
. ***  ********************  .. . *

40. spacer 1.1|3187757|35|NC_006348|PILER-CR matches to NZ_CP022783 (Ralstonia solanacearum strain SL3755 plasmid unnamed, complete sequence) position: , mismatch: 11, identity: 0.686

gccgctgcgcgcacccgcgccgccgccacccgacg	CRISPR spacer
agcgcgtcgcgcacccgcgccgccgcctgttcggg	Protospacer
. ***  ********************  .. . *

41. spacer 1.1|3187757|35|NC_006348|PILER-CR matches to NZ_CP022795 (Ralstonia solanacearum strain SL2330 plasmid unnamed, complete sequence) position: , mismatch: 11, identity: 0.686

gccgctgcgcgcacccgcgccgccgccacccgacg	CRISPR spacer
agcgcgtcgcgcacccgcgccgccgcctgttcggg	Protospacer
. ***  ********************  .. . *

42. spacer 1.1|3187757|35|NC_006348|PILER-CR matches to NZ_CP009763 (Ralstonia solanacearum OE1-1 plasmid unnamed, complete sequence) position: , mismatch: 11, identity: 0.686

gccgctgcgcgcacccgcgccgccgccacccgacg	CRISPR spacer
agcgcgtcgcgcacccgcgccgccgcctgttcggg	Protospacer
. ***  ********************  .. . *

43. spacer 1.1|3187757|35|NC_006348|PILER-CR matches to NZ_CP022779 (Ralstonia solanacearum strain SL3882 plasmid unnamed, complete sequence) position: , mismatch: 11, identity: 0.686

gccgctgcgcgcacccgcgccgccgccacccgacg	CRISPR spacer
agcgcgtcgcgcacccgcgccgccgcctgttcggg	Protospacer
. ***  ********************  .. . *

44. spacer 1.1|3187757|35|NC_006348|PILER-CR matches to NZ_CP052085 (Ralstonia solanacearum strain FJAT15353.F8 plasmid Plas1, complete sequence) position: , mismatch: 11, identity: 0.686

gccgctgcgcgcacccgcgccgccgccacccgacg	CRISPR spacer
agcgcgtcgcgcacccgcgccgccgcctgttcggg	Protospacer
. ***  ********************  .. . *

45. spacer 1.1|3187757|35|NC_006348|PILER-CR matches to NZ_CP052095 (Ralstonia solanacearum strain FJAT15340.F1 plasmid Plas1, complete sequence) position: , mismatch: 11, identity: 0.686

gccgctgcgcgcacccgcgccgccgccacccgacg	CRISPR spacer
agcgcgtcgcgcacccgcgccgccgcctgttcggg	Protospacer
. ***  ********************  .. . *

46. spacer 1.1|3187757|35|NC_006348|PILER-CR matches to NZ_CP052077 (Ralstonia solanacearum strain FJAT445.F50 plasmid Plas1, complete sequence) position: , mismatch: 11, identity: 0.686

gccgctgcgcgcacccgcgccgccgccacccgacg	CRISPR spacer
agcgcgtcgcgcacccgcgccgccgcctgttcggg	Protospacer
. ***  ********************  .. . *

47. spacer 1.1|3187757|35|NC_006348|PILER-CR matches to NZ_CP052087 (Ralstonia solanacearum strain FJAT15353.F50 plasmid Plas1, complete sequence) position: , mismatch: 11, identity: 0.686

gccgctgcgcgcacccgcgccgccgccacccgacg	CRISPR spacer
agcgcgtcgcgcacccgcgccgccgcctgttcggg	Protospacer
. ***  ********************  .. . *

48. spacer 1.1|3187757|35|NC_006348|PILER-CR matches to NZ_CP052097 (Ralstonia solanacearum strain FJAT15304.F6 plasmid Plas1, complete sequence) position: , mismatch: 11, identity: 0.686

gccgctgcgcgcacccgcgccgccgccacccgacg	CRISPR spacer
agcgcgtcgcgcacccgcgccgccgcctgttcggg	Protospacer
. ***  ********************  .. . *

49. spacer 1.1|3187757|35|NC_006348|PILER-CR matches to NZ_CP052127 (Ralstonia solanacearum strain FJAT1303.F50 plasmid Plas1, complete sequence) position: , mismatch: 11, identity: 0.686

gccgctgcgcgcacccgcgccgccgccacccgacg	CRISPR spacer
agcgcgtcgcgcacccgcgccgccgcctgttcggg	Protospacer
. ***  ********************  .. . *

50. spacer 1.1|3187757|35|NC_006348|PILER-CR matches to NZ_CP052079 (Ralstonia solanacearum strain FJAT445.F1 plasmid Plas1, complete sequence) position: , mismatch: 11, identity: 0.686

gccgctgcgcgcacccgcgccgccgccacccgacg	CRISPR spacer
agcgcgtcgcgcacccgcgccgccgcctgttcggg	Protospacer
. ***  ********************  .. . *

51. spacer 1.1|3187757|35|NC_006348|PILER-CR matches to NZ_CP052089 (Ralstonia solanacearum strain FJAT15353.F1 plasmid Plas1, complete sequence) position: , mismatch: 11, identity: 0.686

gccgctgcgcgcacccgcgccgccgccacccgacg	CRISPR spacer
agcgcgtcgcgcacccgcgccgccgcctgttcggg	Protospacer
. ***  ********************  .. . *

52. spacer 1.1|3187757|35|NC_006348|PILER-CR matches to NZ_CP052093 (Ralstonia solanacearum strain FJAT15340.F50 plasmid Plas1, complete sequence) position: , mismatch: 11, identity: 0.686

gccgctgcgcgcacccgcgccgccgccacccgacg	CRISPR spacer
agcgcgtcgcgcacccgcgccgccgcctgttcggg	Protospacer
. ***  ********************  .. . *

53. spacer 1.1|3187757|35|NC_006348|PILER-CR matches to NZ_CP052101 (Ralstonia solanacearum strain FJAT15304.F1 plasmid Plas1, complete sequence) position: , mismatch: 11, identity: 0.686

gccgctgcgcgcacccgcgccgccgccacccgacg	CRISPR spacer
agcgcgtcgcgcacccgcgccgccgcctgttcggg	Protospacer
. ***  ********************  .. . *

54. spacer 1.1|3187757|35|NC_006348|PILER-CR matches to NZ_CP052099 (Ralstonia solanacearum strain FJAT15304.F50 plasmid Plas1, complete sequence) position: , mismatch: 11, identity: 0.686

gccgctgcgcgcacccgcgccgccgccacccgacg	CRISPR spacer
agcgcgtcgcgcacccgcgccgccgcctgttcggg	Protospacer
. ***  ********************  .. . *

55. spacer 1.1|3187757|35|NC_006348|PILER-CR matches to NZ_CP052125 (Ralstonia solanacearum strain FJAT1452.F1 plasmid Plas1, complete sequence) position: , mismatch: 11, identity: 0.686

gccgctgcgcgcacccgcgccgccgccacccgacg	CRISPR spacer
agcgcgtcgcgcacccgcgccgccgcctgttcggg	Protospacer
. ***  ********************  .. . *

56. spacer 1.1|3187757|35|NC_006348|PILER-CR matches to NZ_CP022793 (Ralstonia solanacearum strain SL2729 plasmid unnamed, complete sequence) position: , mismatch: 11, identity: 0.686

gccgctgcgcgcacccgcgccgccgccacccgacg	CRISPR spacer
agcgcgtcgcgcacccgcgccgccgcctgttcggg	Protospacer
. ***  ********************  .. . *

57. spacer 1.1|3187757|35|NC_006348|PILER-CR matches to NZ_CP022785 (Ralstonia solanacearum strain SL3730 plasmid unnamed, complete sequence) position: , mismatch: 11, identity: 0.686

gccgctgcgcgcacccgcgccgccgccacccgacg	CRISPR spacer
agcgcgtcgcgcacccgcgccgccgcctgttcggg	Protospacer
. ***  ********************  .. . *

58. spacer 1.1|3187757|35|NC_006348|PILER-CR matches to NZ_CP022787 (Ralstonia solanacearum strain SL3300 plasmid unnamed, complete sequence) position: , mismatch: 11, identity: 0.686

gccgctgcgcgcacccgcgccgccgccacccgacg	CRISPR spacer
agcgcgtcgcgcacccgcgccgccgcctgttcggg	Protospacer
. ***  ********************  .. . *

59. spacer 1.1|3187757|35|NC_006348|PILER-CR matches to NZ_CP022756 (Ralstonia solanacearum strain T117 plasmid unnamed, complete sequence) position: , mismatch: 11, identity: 0.686

gccgctgcgcgcacccgcgccgccgccacccgacg	CRISPR spacer
agcgcgtcgcgcacccgcgccgccgcctgttcggg	Protospacer
. ***  ********************  .. . *

60. spacer 1.1|3187757|35|NC_006348|PILER-CR matches to NZ_CP052123 (Ralstonia solanacearum strain FJAT1452.F50 plasmid Plas1, complete sequence) position: , mismatch: 11, identity: 0.686

gccgctgcgcgcacccgcgccgccgccacccgacg	CRISPR spacer
agcgcgtcgcgcacccgcgccgccgcctgttcggg	Protospacer
. ***  ********************  .. . *

61. spacer 1.1|3187757|35|NC_006348|PILER-CR matches to NZ_CP052131 (Ralstonia solanacearum strain FJAT1303.F8 plasmid Plas1, complete sequence) position: , mismatch: 11, identity: 0.686

gccgctgcgcgcacccgcgccgccgccacccgacg	CRISPR spacer
agcgcgtcgcgcacccgcgccgccgcctgttcggg	Protospacer
. ***  ********************  .. . *

62. spacer 1.1|3187757|35|NC_006348|PILER-CR matches to NZ_CP052081 (Ralstonia solanacearum strain FJAT442.F50 plasmid Plas1, complete sequence) position: , mismatch: 11, identity: 0.686

gccgctgcgcgcacccgcgccgccgccacccgacg	CRISPR spacer
agcgcgtcgcgcacccgcgccgccgcctgttcggg	Protospacer
. ***  ********************  .. . *

63. spacer 1.1|3187757|35|NC_006348|PILER-CR matches to NZ_CP052083 (Ralstonia solanacearum strain FJAT442.F1 plasmid Plas1, complete sequence) position: , mismatch: 11, identity: 0.686

gccgctgcgcgcacccgcgccgccgccacccgacg	CRISPR spacer
agcgcgtcgcgcacccgcgccgccgcctgttcggg	Protospacer
. ***  ********************  .. . *

64. spacer 1.1|3187757|35|NC_006348|PILER-CR matches to NZ_CP052091 (Ralstonia solanacearum strain FJAT15340.F6 plasmid Plas1, complete sequence) position: , mismatch: 11, identity: 0.686

gccgctgcgcgcacccgcgccgccgccacccgacg	CRISPR spacer
agcgcgtcgcgcacccgcgccgccgcctgttcggg	Protospacer
. ***  ********************  .. . *

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

92271 : 156368

Leptospira_phage(12.5%)

tRNA,transposase,protease,portal

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_004191998.1\|92271_93735_+\|transposase	IS1182-like element ISBma2 family transposase	A0A1X9I5T2	Streptococcus_phage	8.8e-80	38.6
WP_004189319.1\|93840_94164_-	DUF1840 domain-containing protein	NA	NA	NA	NA
WP_004189649.1\|94366_96151_+\|tRNA	arginine--tRNA ligase	NA	NA	NA	NA
WP_004197747.1\|96229_97078_+	SPOR domain-containing protein	NA	NA	NA	NA
WP_004190112.1\|97129_97768_+	thiol:disulfide interchange protein DsbA	NA	NA	NA	NA
WP_004190175.1\|97784_98564_+	SDR family oxidoreductase	NA	NA	NA	NA
WP_004203497.1\|98716_99430_-	SDR family oxidoreductase	NA	NA	NA	NA
WP_004189957.1\|99720_100137_+	MarR family transcriptional regulator	NA	NA	NA	NA
WP_004190133.1\|100647_102234_+	ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_004189357.1\|102467_104114_+	ABC-F family ATP-binding cassette domain-containing protein	A0A2I4R674	Erysipelothrix_phage	1.5e-19	26.1
WP_004189449.1\|104408_105488_-	MBL fold metallo-hydrolase	NA	NA	NA	NA
WP_004525974.1\|105777_107589_+	bifunctional isocitrate dehydrogenase kinase/phosphatase	NA	NA	NA	NA
WP_004189176.1\|107646_108417_+	carbonate dehydratase	NA	NA	NA	NA
WP_004190136.1\|108403_109597_+	acetyl-CoA C-acetyltransferase	NA	NA	NA	NA
WP_004189135.1\|109627_110311_+	SDR family oxidoreductase	Q56AQ6	Bacillus_thuringiensis_phage	9.7e-05	30.7
WP_004188900.1\|110342_110795_+	YchJ family protein	NA	NA	NA	NA
WP_004189232.1\|112863_114210_+	adenosylmethionine--8-amino-7-oxononanoate transaminase	NA	NA	NA	NA
WP_004189736.1\|114206_115391_+	8-amino-7-oxononanoate synthase	G9E4Q1	Emiliania_huxleyi_virus	3.9e-17	24.1
WP_004189380.1\|115387_116110_+	dethiobiotin synthase	NA	NA	NA	NA
WP_004200336.1\|116182_117193_+	biotin synthase BioB	NA	NA	NA	NA
WP_004190017.1\|117319_118033_-	copper homeostasis protein CutC	NA	NA	NA	NA
WP_004197753.1\|118411_119248_-	hypothetical protein	NA	NA	NA	NA
WP_004189785.1\|119253_120657_-	alkaline phosphatase	NA	NA	NA	NA
WP_024900437.1\|120689_122129_-	alkaline phosphatase	NA	NA	NA	NA
WP_004205137.1\|122419_122800_-	hypothetical protein	NA	NA	NA	NA
WP_038802950.1\|123793_124914_-\|transposase	IS3 family transposase	S5WIU1	Leptospira_phage	3.6e-49	39.5
WP_004197759.1\|125291_125846_+	YaeQ family protein	NA	NA	NA	NA
WP_004197761.1\|126045_126462_-	VOC family protein	NA	NA	NA	NA
WP_004190110.1\|126863_127958_+	bifunctional DNA-binding transcriptional regulator/O6-methylguanine-DNA methyltransferase Ada	A0A0G2Y1B6	Acanthamoeba_polyphaga_mimivirus	3.8e-19	37.4
WP_004200726.1\|127954_128896_+	DNA-3-methyladenine glycosylase 2 family protein	NA	NA	NA	NA
WP_004200727.1\|129055_130669_+	glutamate--cysteine ligase	NA	NA	NA	NA
WP_004189592.1\|130687_132136_-	RNA polymerase sigma factor RpoD/SigA	A0A2I7SAT0	Vibrio_phage	4.9e-30	33.5
WP_004189689.1\|132399_132948_-	hypothetical protein	NA	NA	NA	NA
WP_004189874.1\|133540_134110_-	Spy/CpxP family protein refolding chaperone	NA	NA	NA	NA
WP_004189434.1\|134212_135181_-	LysR family transcriptional regulator	NA	NA	NA	NA
WP_004201742.1\|135323_136418_+	polyamine ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_004190014.1\|136446_137559_+	histone deacetylase	A0A2K9KZC4	Tupanvirus	3.2e-37	30.8
WP_004189258.1\|137569_138445_+	N-carbamoylputrescine amidase	A7IVZ1	Paramecium_bursaria_Chlorella_virus	9.6e-74	47.3
WP_004200729.1\|138581_138992_-	hypothetical protein	NA	NA	NA	NA
WP_004200730.1\|139390_140482_+\|portal	phage portal protein	A4JWQ2	Burkholderia_virus	2.0e-193	92.3
WP_004188977.1\|140554_140839_-	hypothetical protein	NA	NA	NA	NA
WP_004200731.1\|140835_141318_-	DUF2778 domain-containing protein	NA	NA	NA	NA
WP_096325434.1\|141369_142490_-\|transposase	IS3 family transposase	S5WIU1	Leptospira_phage	3.6e-49	39.5
WP_004187628.1\|142670_143891_-\|transposase	ISL3-like element ISBma1 family transposase	A9YX10	Burkholderia_phage	7.8e-239	99.5
WP_004200732.1\|144281_144686_+	PaaI family thioesterase	NA	NA	NA	NA
WP_004189208.1\|144723_145593_+	patatin-like phospholipase family protein	NA	NA	NA	NA
WP_004188904.1\|145713_146730_-	D-2-hydroxyacid dehydrogenase family protein	NA	NA	NA	NA
WP_004189230.1\|147179_148235_+	LysR family transcriptional regulator	NA	NA	NA	NA
WP_004200734.1\|148456_151066_-	DNA topoisomerase III	A0A2P1ELA0	Moumouvirus	7.7e-18	25.7
WP_004190199.1\|151276_151648_-	thioredoxin family protein	NA	NA	NA	NA
WP_004190020.1\|151707_152898_-	DNA-protecting protein DprA	S6BFL3	Thermus_phage	2.0e-21	39.2
WP_004201745.1\|153126_153630_+	peptide deformylase	A0A067XQZ3	Caulobacter_phage	2.7e-12	34.3
WP_004200737.1\|153661_154645_+\|tRNA	methionyl-tRNA formyltransferase	E3SNR5	Prochlorococcus_phage	1.3e-07	38.0
WP_004189288.1\|154765_155401_+	LysE family translocator	NA	NA	NA	NA
WP_004189409.1\|155510_156368_+\|protease	zinc metalloprotease HtpX	NA	NA	NA	NA

DBSCAN-SWA_2

438614 : 447444

Tanapox_virus(16.67%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_004190087.1\|438614_439457_+	alpha/beta hydrolase	A7XCB7	Tanapox_virus	7.2e-18	27.2
WP_004188957.1\|439799_440723_-	histone deacetylase family protein	A0A2K9KZC4	Tupanvirus	8.4e-44	36.5
WP_004195984.1\|440901_442197_+	lytic murein transglycosylase B	NA	NA	NA	NA
WP_004532363.1\|442422_443325_-	cysteine synthase CysM	A0A1X9I5F1	Streptococcus_phage	1.9e-53	39.9
WP_004189725.1\|443648_443966_-	helix-hairpin-helix domain-containing protein	NA	NA	NA	NA
WP_004190173.1\|444037_445030_-	ADP-glyceromanno-heptose 6-epimerase	R9S880	Prochlorococcus_phage	9.1e-28	30.9
WP_004189069.1\|445088_446012_-	D-glycero-beta-D-manno-heptose-7-phosphate kinase	A0A2H4N7X4	Lake_Baikal_phage	1.3e-15	26.8
WP_004189214.1\|446043_447444_-	UDP-glucose/GDP-mannose dehydrogenase family protein	A0A127AXI2	Bacillus_phage	2.1e-78	38.3

DBSCAN-SWA_3

465302 : 527617

Leptospira_phage(27.27%)

integrase,transposase

attL 465255:465314|attR 528283:529519

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
465255:465314	attL	NA	NA	NA	NA
WP_038802950.1\|465302_466423_-\|transposase	IS3 family transposase	S5WIU1	Leptospira_phage	3.6e-49	39.5
WP_004195992.1\|467839_468484_+	phospholipid methyltransferase	NA	NA	NA	NA
WP_004189371.1\|468664_468928_-	hypothetical protein	NA	NA	NA	NA
WP_004195993.1\|469029_470136_-	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_004189882.1\|470266_470740_+	NAD(P)H-dependent oxidoreductase subunit E	NA	NA	NA	NA
WP_004189204.1\|470736_472302_+	formate dehydrogenase beta subunit	NA	NA	NA	NA
WP_004195994.1\|472316_475271_+	formate dehydrogenase subunit alpha	NA	NA	NA	NA
WP_004190152.1\|475278_475539_+	formate dehydrogenase subunit delta	NA	NA	NA	NA
WP_004189778.1\|475914_477561_-	FAD-dependent monooxygenase	NA	NA	NA	NA
WP_004189933.1\|477714_479559_+	tetratricopeptide repeat protein	F2Y1J7	Organic_Lake_phycodnavirus	1.7e-11	32.2
WP_004188918.1\|479947_481243_-	MFS transporter	Q6JIH2	Burkholderia_virus	3.2e-65	37.5
WP_073699190.1\|481296_481521_-	hypothetical protein	NA	NA	NA	NA
WP_004189943.1\|481731_483066_-	gamma-glutamyl-gamma-aminobutyrate hydrolase	NA	NA	NA	NA
WP_004550105.1\|483668_485045_+	amidase	NA	NA	NA	NA
WP_004189653.1\|485153_485663_+	disulfide bond formation protein B	NA	NA	NA	NA
WP_004189595.1\|486171_487194_+	xanthine dehydrogenase accessory protein XdhC	A0A0P0IKN7	Acinetobacter_phage	1.1e-44	37.8
WP_004189005.1\|487235_488261_+	adenosine deaminase	NA	NA	NA	NA
WP_004189169.1\|488348_489725_+	NCS2 family permease	NA	NA	NA	NA
WP_004189962.1\|489750_491061_+	guanine deaminase	NA	NA	NA	NA
WP_004189913.1\|491548_492121_+	TMEM165/GDT1 family protein	NA	NA	NA	NA
WP_004189569.1\|492454_493168_-	DUF4136 domain-containing protein	NA	NA	NA	NA
WP_004189242.1\|493226_493364_-	hypothetical protein	NA	NA	NA	NA
WP_004189239.1\|493388_496091_+	aminopeptidase N	NA	NA	NA	NA
WP_004189599.1\|496438_498733_-	5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase	NA	NA	NA	NA
WP_004189234.1\|498849_499782_+	LysR family transcriptional regulator	NA	NA	NA	NA
WP_004189384.1\|499911_500928_+	class 1 fructose-bisphosphatase	A0A1V0SKX4	Klosneuvirus	5.4e-52	36.4
WP_004186184.1\|501275_502496_+\|transposase	ISL3-like element ISBma1 family transposase	A9YX10	Burkholderia_phage	6.6e-238	99.0
WP_004190100.1\|502837_503098_+	hypothetical protein	NA	NA	NA	NA
WP_004197792.1\|503120_503597_+	hypothetical protein	NA	NA	NA	NA
WP_004197793.1\|503852_504068_-	hypothetical protein	NA	NA	NA	NA
WP_004197795.1\|504767_505019_+	GlsB/YeaQ/YmgE family stress response membrane protein	NA	NA	NA	NA
WP_004189798.1\|505305_505794_-	hypothetical protein	NA	NA	NA	NA
WP_004189437.1\|505790_507041_-	exo-alpha-sialidase	NA	NA	NA	NA
WP_004188913.1\|507049_509386_-	TonB-dependent receptor	NA	NA	NA	NA
WP_004189159.1\|509532_509922_-	DUF2946 domain-containing protein	NA	NA	NA	NA
WP_004189224.1\|510127_510274_+	hypothetical protein	NA	NA	NA	NA
WP_011203825.1\|510534_511128_+	chorismate mutase	NA	NA	NA	NA
WP_004197797.1\|511124_511283_-	glycosyl transferase family 2	NA	NA	NA	NA
WP_038802950.1\|511689_512810_-\|transposase	IS3 family transposase	S5WIU1	Leptospira_phage	3.6e-49	39.5
WP_004189780.1\|513024_513603_-	pseudouridine synthase	NA	NA	NA	NA
WP_004189552.1\|513870_515130_+	NADP-dependent isocitrate dehydrogenase	Q77Z09	Phage_21	5.2e-12	63.0
WP_004189626.1\|515102_515285_-	hypothetical protein	NA	NA	NA	NA
WP_004189292.1\|515297_516908_+	multicopper oxidase family protein	NA	NA	NA	NA
WP_004191998.1\|517066_518530_+\|transposase	IS1182-like element ISBma2 family transposase	A0A1X9I5T2	Streptococcus_phage	8.8e-80	38.6
WP_004189917.1\|521368_522079_-	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_162473585.1\|522637_522844_+	hypothetical protein	NA	NA	NA	NA
WP_004190145.1\|523031_523538_+	acyl-CoA thioesterase	NA	NA	NA	NA
WP_004189867.1\|524016_525411_-	class II fumarate hydratase	NA	NA	NA	NA
WP_004197806.1\|525425_525599_+	hypothetical protein	NA	NA	NA	NA
WP_038802950.1\|525794_526915_-\|transposase	IS3 family transposase	S5WIU1	Leptospira_phage	3.6e-49	39.5
WP_004189968.1\|526945_527617_-\|integrase	integrase arm-type DNA-binding domain-containing protein	B7SYF8	Stenotrophomonas_phage	1.3e-46	46.1
528283:529519	attR	NA	NA	NA	NA

DBSCAN-SWA_4

748164 : 811650

Leptospira_phage(12.5%)

transposase,coat,protease

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_038802950.1\|748164_749284_+\|transposase	IS3 family transposase	S5WIU1	Leptospira_phage	3.6e-49	39.5
WP_004191842.1\|749908_750619_-	molecular chaperone	NA	NA	NA	NA
WP_004526328.1\|750626_751145_-\|coat	spore coat U domain-containing protein	NA	NA	NA	NA
WP_004193822.1\|751518_752529_+\|coat	spore coat U domain-containing protein	NA	NA	NA	NA
WP_004192784.1\|752701_753517_-	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_004192680.1\|753699_754455_+	class I SAM-dependent methyltransferase	NA	NA	NA	NA
WP_004191998.1\|754830_756294_-\|transposase	IS1182-like element ISBma2 family transposase	A0A1X9I5T2	Streptococcus_phage	8.8e-80	38.6
WP_004191560.1\|756439_759424_-	phosphoenolpyruvate carboxylase	NA	NA	NA	NA
WP_004193185.1\|759750_760740_+	hydroxymethylbilane synthase	NA	NA	NA	NA
WP_004193146.1\|760739_762719_+	fused uroporphyrinogen-III synthase HemD/membrane protein HemX	NA	NA	NA	NA
WP_004193604.1\|762723_763914_+	heme biosynthesis protein HemY	NA	NA	NA	NA
WP_004192161.1\|764094_765402_-	MFS transporter	NA	NA	NA	NA
WP_004192728.1\|765440_766199_-	SDR family oxidoreductase	NA	NA	NA	NA
WP_004193515.1\|766287_767727_-	aldehyde dehydrogenase family protein	NA	NA	NA	NA
WP_004192356.1\|767887_768415_+	inorganic diphosphatase	A0A2H4J8U1	uncultured_Caudovirales_phage	9.0e-51	53.8
WP_004199405.1\|768473_769370_-	GIY-YIG nuclease family protein	W8W2G4	Invertebrate_iridovirus	2.1e-07	43.1
WP_011807749.1\|769348_769738_-	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_004192390.1\|770369_771548_-	N-acetyltransferase	NA	NA	NA	NA
WP_004198600.1\|771668_773369_+	NAD+ synthase	A0A2L0UZF5	Agrobacterium_phage	5.8e-91	36.8
WP_004193987.1\|773429_773768_+	P-II family nitrogen regulator	NA	NA	NA	NA
WP_004191758.1\|774236_775325_-	porin	NA	NA	NA	NA
WP_004553879.1\|776219_776999_-	ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	3.9e-26	40.0
WP_004193161.1\|777021_777735_-	ABC transporter permease	NA	NA	NA	NA
WP_004191164.1\|777731_778421_-	histidine ABC transporter permease HisQ	NA	NA	NA	NA
WP_004198602.1\|778631_779408_-	ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_004192043.1\|780835_781381_-	periplasmic heavy metal sensor	NA	NA	NA	NA
WP_004191521.1\|781622_782321_+	response regulator	W8CYM9	Bacillus_phage	2.9e-28	36.7
WP_004193003.1\|782304_783618_+	HAMP domain-containing protein	NA	NA	NA	NA
WP_004198606.1\|783691_783958_-	hypothetical protein	NA	NA	NA	NA
WP_004193300.1\|784084_784222_-	hypothetical protein	NA	NA	NA	NA
WP_004192556.1\|784454_786212_+	ABC transporter permease subunit	NA	NA	NA	NA
WP_004192968.1\|786265_787606_+	nitrate/sulfonate/bicarbonate ABC transporter ATP-binding protein	G3M9Y6	Bacillus_virus	8.2e-32	37.7
WP_038802950.1\|788070_789191_-\|transposase	IS3 family transposase	S5WIU1	Leptospira_phage	3.6e-49	39.5
WP_004198608.1\|790188_791676_-	glycine betaine/L-proline transporter ProP	Q6JIH2	Burkholderia_virus	8.7e-59	33.0
WP_004193459.1\|792210_792543_+	YnfA family protein	A0A218MNG8	uncultured_virus	2.0e-24	57.6
WP_004531112.1\|792975_793698_-	DNA polymerase III subunit epsilon	A0A1X9SH08	Bradyrhizobium_phage	1.7e-39	40.0
WP_004193456.1\|793755_794202_-	ribonuclease HI	J9Q745	Salmonella_phage	1.2e-43	53.1
WP_004192921.1\|794198_795011_-	class I SAM-dependent methyltransferase	NA	NA	NA	NA
WP_004192690.1\|795031_795838_+	hydroxyacylglutathione hydrolase	NA	NA	NA	NA
WP_004192263.1\|795990_797583_+	transglycosylase SLT domain-containing protein	U5PVY0	Bacillus_phage	2.2e-07	37.2
WP_004198692.1\|797717_798956_+	MFS transporter	NA	NA	NA	NA
WP_004193049.1\|799062_800205_-	hypothetical protein	NA	NA	NA	NA
WP_004192764.1\|800432_801455_+	AraC family transcriptional regulator	NA	NA	NA	NA
WP_004198695.1\|801871_803017_+	glutamine-hydrolyzing carbamoyl-phosphate synthase small subunit	R4TGJ8	Halovirus	2.2e-46	34.0
WP_004192135.1\|803048_803711_+	leucine efflux protein LeuE	NA	NA	NA	NA
WP_004193866.1\|803762_807017_+	carbamoyl-phosphate synthase large subunit	NA	NA	NA	NA
WP_004192392.1\|807135_807612_+	transcription elongation factor GreA	NA	NA	NA	NA
WP_004192787.1\|807611_808115_+	DUF4149 domain-containing protein	NA	NA	NA	NA
WP_004193985.1\|808185_808740_-	YhbY family RNA-binding protein	NA	NA	NA	NA
WP_004193119.1\|808933_809596_+	RlmE family RNA methyltransferase	NA	NA	NA	NA
WP_004191694.1\|809763_811650_+\|protease	ATP-dependent zinc metalloprotease FtsH	M4QMW8	Micromonas_pusilla_virus	5.6e-111	40.8

DBSCAN-SWA_5

839282 : 909399

Leptospira_phage(28.57%)

coat,transposase,plate

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_038802950.1\|839282_840402_+\|transposase	IS3 family transposase	S5WIU1	Leptospira_phage	3.6e-49	39.5
WP_073699268.1\|840447_841038_-	hypothetical protein	NA	NA	NA	NA
WP_004193369.1\|841379_841886_-	DUF4123 domain-containing protein	A4PE24	Ralstonia_virus	5.1e-19	39.4
WP_004191223.1\|841882_842308_-	PAAR domain-containing protein	A4JWV5	Burkholderia_virus	1.3e-15	50.6
WP_004193964.1\|843053_844946_+	SAM-dependent methyltransferase	NA	NA	NA	NA
WP_004191686.1\|845012_846473_-	PLP-dependent aminotransferase family protein	NA	NA	NA	NA
WP_004197687.1\|846695_847073_+	nuclear transport factor 2 family protein	NA	NA	NA	NA
WP_004266563.1\|847096_847675_+	flavodoxin family protein	NA	NA	NA	NA
WP_004197691.1\|847889_850682_-	malto-oligosyltrehalose synthase	NA	NA	NA	NA
WP_004191844.1\|850678_852901_-	4-alpha-glucanotransferase	NA	NA	NA	NA
WP_004191214.1\|852897_854640_-	malto-oligosyltrehalose trehalohydrolase	NA	NA	NA	NA
WP_004192927.1\|854666_856775_-	glycogen debranching protein GlgX	NA	NA	NA	NA
WP_004193375.1\|859036_862432_-	maltose alpha-D-glucosyltransferase	NA	NA	NA	NA
WP_011832205.1\|862428_865776_-	alpha-1,4-glucan--maltose-1-phosphate maltosyltransferase	NA	NA	NA	NA
WP_004193933.1\|866329_867808_-	PHB depolymerase family esterase	NA	NA	NA	NA
WP_004192837.1\|868515_868734_-	hypothetical protein	NA	NA	NA	NA
WP_162473587.1\|869218_869530_-	hypothetical protein	NA	NA	NA	NA
WP_004193316.1\|869712_870036_+	hypothetical protein	NA	NA	NA	NA
WP_004193478.1\|870319_871744_+	hypothetical protein	NA	NA	NA	NA
WP_004193589.1\|872010_872988_+	LysR family transcriptional regulator	NA	NA	NA	NA
WP_004526732.1\|873401_874184_+	response regulator transcription factor	NA	NA	NA	NA
WP_004192729.1\|874367_874583_+	DUF3955 domain-containing protein	NA	NA	NA	NA
WP_004196673.1\|874593_874965_+	YcgJ family protein	NA	NA	NA	NA
WP_004196675.1\|875016_875352_-	hypothetical protein	NA	NA	NA	NA
WP_004196677.1\|875958_876654_+	response regulator transcription factor	NA	NA	NA	NA
WP_004191391.1\|877029_880302_+	YadA-like family protein	A0A2C9CZB7	Yersinia_phage	1.4e-05	33.0
WP_004191672.1\|880382_881093_+	OmpA family protein	NA	NA	NA	NA
WP_004192726.1\|881094_882624_+	hypothetical protein	D6PFH9	uncultured_phage	1.2e-15	25.4
WP_004191318.1\|882640_882985_+	H-NS histone family protein	NA	NA	NA	NA
WP_004193132.1\|883407_883650_-	hypothetical protein	NA	NA	NA	NA
WP_004193698.1\|883695_884256_-	SCO family protein	NA	NA	NA	NA
WP_004191878.1\|884290_884779_-	hypothetical protein	NA	NA	NA	NA
WP_004196681.1\|884805_887208_-	RICIN domain-containing protein	NA	NA	NA	NA
WP_004196682.1\|887460_887694_-	hypothetical protein	NA	NA	NA	NA
WP_009966472.1\|888740_888869_-	hypothetical protein	NA	NA	NA	NA
WP_004192127.1\|889862_891713_+\|plate	type VI secretion system baseplate subunit TssF	NA	NA	NA	NA
WP_004193292.1\|891740_893156_-	hypothetical protein	NA	NA	NA	NA
WP_004193592.1\|893179_893446_-	PAAR domain-containing protein	NA	NA	NA	NA
WP_004192367.1\|893705_893933_-	hypothetical protein	NA	NA	NA	NA
WP_004196687.1\|893966_896774_+	type VI secretion system tip protein VgrG	A0A2H4JCD4	uncultured_Caudovirales_phage	4.0e-28	25.1
WP_004192570.1\|896776_897610_+	DUF4123 domain-containing protein	NA	NA	NA	NA
WP_038802950.1\|897843_898964_-\|transposase	IS3 family transposase	S5WIU1	Leptospira_phage	3.6e-49	39.5
WP_004193170.1\|899710_901024_+	Nramp family divalent metal transporter	NA	NA	NA	NA
WP_004191144.1\|901918_902188_+	hypothetical protein	NA	NA	NA	NA
WP_004193855.1\|902440_902722_-	H-NS histone family protein	NA	NA	NA	NA
WP_004192394.1\|903189_904182_-	amidohydrolase family protein	NA	NA	NA	NA
WP_004196700.1\|904226_905423_-	MFS transporter	NA	NA	NA	NA
WP_004196705.1\|905929_906823_+	LysR family transcriptional regulator	NA	NA	NA	NA
WP_004531175.1\|907160_907382_+	hypothetical protein	NA	NA	NA	NA
WP_004192149.1\|907639_908185_+\|coat	spore coat protein U domain-containing protein	NA	NA	NA	NA
WP_004191870.1\|908237_908798_+\|coat	spore coat protein U domain-containing protein	NA	NA	NA	NA
WP_004526783.1\|908874_909399_+\|coat	spore coat protein U domain-containing protein	NA	NA	NA	NA

DBSCAN-SWA_6

1065777 : 1128264

Leptospira_phage(33.33%)

tRNA,transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_004190171.1\|1065777_1066998_+\|transposase	ISL3-like element ISBma1 family transposase	A9YX10	Burkholderia_phage	1.0e-238	99.3
WP_004191349.1\|1068734_1069505_+	molecular chaperone	NA	NA	NA	NA
WP_004193303.1\|1069562_1072064_+	fimbrial biogenesis outer membrane usher protein	NA	NA	NA	NA
WP_004193791.1\|1072054_1073026_+	type 1 fimbrial protein	NA	NA	NA	NA
WP_004197781.1\|1074197_1077236_+	YadA-like family protein	NA	NA	NA	NA
WP_073699454.1\|1077952_1078135_-	hypothetical protein	NA	NA	NA	NA
WP_004199437.1\|1078693_1079077_+	hypothetical protein	NA	NA	NA	NA
WP_004193126.1\|1079374_1080040_+	response regulator transcription factor	NA	NA	NA	NA
WP_004191146.1\|1080039_1080186_+	hypothetical protein	NA	NA	NA	NA
WP_162473478.1\|1081213_1081462_-	hypothetical protein	NA	NA	NA	NA
WP_004192661.1\|1081630_1084003_-	penicillin acylase family protein	NA	NA	NA	NA
WP_004197788.1\|1084127_1085303_-	carbamoyltransferase	E3SL71	Synechococcus_phage	1.8e-46	35.9
WP_038802950.1\|1085390_1086510_+\|transposase	IS3 family transposase	S5WIU1	Leptospira_phage	3.6e-49	39.5
WP_004521662.1\|1086802_1087117_-	hypothetical protein	NA	NA	NA	NA
WP_004191362.1\|1087016_1088570_+	collagen-like triple helix repeat-containing protein	NA	NA	NA	NA
WP_004192734.1\|1088619_1089885_+	collagen-like triple helix repeat-containing protein	NA	NA	NA	NA
WP_004193874.1\|1090059_1091715_+	ShlB/FhaC/HecB family hemolysin secretion/activation protein	NA	NA	NA	NA
WP_004193599.1\|1091958_1092420_+	DUF2147 domain-containing protein	NA	NA	NA	NA
WP_004191720.1\|1092656_1093067_-\|transposase	transposase	NA	NA	NA	NA
WP_004550551.1\|1093261_1094359_-	cell division protein ZapE	NA	NA	NA	NA
WP_004191219.1\|1094465_1095896_-	dihydrolipoyl dehydrogenase	A0A2K5B2C5	Erysipelothrix_phage	1.9e-42	27.8
WP_004192735.1\|1095995_1097270_-	2-oxoglutarate dehydrogenase complex dihydrolipoyllysine-residue succinyltransferase	NA	NA	NA	NA
WP_004191889.1\|1097397_1100262_-	2-oxoglutarate dehydrogenase E1 component	NA	NA	NA	NA
WP_004193111.1\|1100600_1102427_-	translational GTPase TypA	NA	NA	NA	NA
WP_004192835.1\|1102719_1103217_+	MarR family transcriptional regulator	NA	NA	NA	NA
WP_004191557.1\|1103316_1104813_+	efflux transporter outer membrane subunit	NA	NA	NA	NA
WP_004192058.1\|1104880_1106116_+	efflux RND transporter periplasmic adaptor subunit	NA	NA	NA	NA
WP_004193982.1\|1106138_1107698_+	DHA2 family efflux MFS transporter permease subunit	NA	NA	NA	NA
WP_011203915.1\|1107968_1108904_-\|tRNA	tRNA pseudouridine(55) synthase TruB	NA	NA	NA	NA
WP_004199441.1\|1108930_1109299_-	30S ribosome-binding factor RbfA	NA	NA	NA	NA
WP_004197388.1\|1109404_1112332_-	translation initiation factor IF-2	A0A2H4UTS4	Bodo_saltans_virus	5.2e-23	25.3
WP_004193517.1\|1112423_1113899_-	transcription termination/antitermination protein NusA	NA	NA	NA	NA
WP_004193908.1\|1113895_1114357_-	ribosome maturation factor RimP	NA	NA	NA	NA
WP_004191876.1\|1114661_1116326_-	pseudouridine synthase	NA	NA	NA	NA
WP_004192767.1\|1116389_1117718_-	SMC-Scp complex subunit ScpB	A0A1B1IVT7	uncultured_Mediterranean_phage	5.3e-23	35.1
WP_004193481.1\|1118136_1119039_-	LysR family transcriptional regulator	A0A2P0ZL89	Lactobacillus_phage	4.5e-10	23.6
WP_004199443.1\|1119457_1119859_+\|transposase	transposase	NA	NA	NA	NA
WP_004521676.1\|1120064_1120322_+	hypothetical protein	NA	NA	NA	NA
WP_004199444.1\|1120480_1120798_-	hypothetical protein	NA	NA	NA	NA
WP_004192638.1\|1120998_1121721_+	YdcF family protein	NA	NA	NA	NA
WP_004192834.1\|1121959_1122238_+	hypothetical protein	NA	NA	NA	NA
WP_004191628.1\|1122386_1122644_+	hypothetical protein	NA	NA	NA	NA
WP_004193694.1\|1122693_1122984_-	antibiotic biosynthesis monooxygenase	NA	NA	NA	NA
WP_096325460.1\|1123383_1124504_-\|transposase	IS3 family transposase	S5WIU1	Leptospira_phage	3.6e-49	39.5
WP_004205956.1\|1125323_1126529_-	outer membrane protein assembly factor BamC	NA	NA	NA	NA
WP_038802950.1\|1127144_1128264_+\|transposase	IS3 family transposase	S5WIU1	Leptospira_phage	3.6e-49	39.5

DBSCAN-SWA_7

2309241 : 2364734

Leptospira_phage(18.75%)

tRNA,transposase,protease

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_038802333.1\|2309241_2310361_+\|transposase	IS3 family transposase	S5WIU1	Leptospira_phage	3.6e-49	39.5
WP_004200457.1\|2310623_2311112_-	hypothetical protein	NA	NA	NA	NA
WP_004191998.1\|2311413_2312877_+\|transposase	IS1182-like element ISBma2 family transposase	A0A1X9I5T2	Streptococcus_phage	8.8e-80	38.6
WP_004186453.1\|2312999_2313980_-	4-hydroxy-3-methylbut-2-enyl diphosphate reductase	NA	NA	NA	NA
WP_004186190.1\|2313982_2314438_-	peptidylprolyl isomerase	NA	NA	NA	NA
WP_004185928.1\|2314576_2315413_+	DNA repair protein RadC	NA	NA	NA	NA
WP_004186391.1\|2315706_2315940_+	50S ribosomal protein L28	NA	NA	NA	NA
WP_004185395.1\|2315957_2316125_+	50S ribosomal protein L33	NA	NA	NA	NA
WP_004186553.1\|2316181_2317894_+	L-aspartate oxidase	NA	NA	NA	NA
WP_004185611.1\|2318085_2318970_-	carboxylating nicotinate-nucleotide diphosphorylase	NA	NA	NA	NA
WP_004185886.1\|2318966_2320103_-	quinolinate synthase NadA	NA	NA	NA	NA
WP_004186237.1\|2320271_2321468_-	fatty acid desaturase	NA	NA	NA	NA
WP_004186398.1\|2321664_2323017_-	mechanosensitive ion channel	NA	NA	NA	NA
WP_004186079.1\|2323028_2324291_-	RsmB/NOP family class I SAM-dependent RNA methyltransferase	NA	NA	NA	NA
WP_004185746.1\|2324287_2324950_-	phosphoribosylglycinamide formyltransferase	E3SNR5	Prochlorococcus_phage	1.6e-25	40.0
WP_004535897.1\|2325074_2326067_+	bifunctional riboflavin kinase/FAD synthetase	NA	NA	NA	NA
WP_004185348.1\|2326178_2329016_+\|tRNA	isoleucine--tRNA ligase	A0A1V0SJ93	Klosneuvirus	1.6e-80	26.0
WP_004186086.1\|2329015_2329516_+	lipoprotein signal peptidase	NA	NA	NA	NA
WP_004186216.1\|2329577_2330789_+	bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase CoaBC	Q9HH70	Methanothermobacter_phage	3.0e-41	31.9
WP_004186718.1\|2330852_2331299_+	dUTP diphosphatase	Q2NP83	Xanthomonas_phage	7.9e-48	64.4
WP_004185819.1\|2331387_2332170_-	membrane protein	NA	NA	NA	NA
WP_004185697.1\|2332334_2333081_-	hypothetical protein	NA	NA	NA	NA
WP_038802950.1\|2333320_2334441_-\|transposase	IS3 family transposase	S5WIU1	Leptospira_phage	3.6e-49	39.5
WP_071810810.1\|2334628_2334847_+	hypothetical protein	NA	NA	NA	NA
WP_004185496.1\|2335044_2335554_+	DUF192 domain-containing protein	A0A1B1IUW8	uncultured_Mediterranean_phage	5.5e-13	41.2
WP_004197486.1\|2335854_2337969_+	elongation factor G	E4ZFJ7	Streptococcus_phage	5.8e-56	26.7
WP_162473589.1\|2338417_2339470_-	hypothetical protein	NA	NA	NA	NA
WP_085962729.1\|2339706_2340885_+	pentapeptide repeat-containing protein	NA	NA	NA	NA
WP_004186341.1\|2341224_2342070_-	aldo/keto reductase	A0A2H4PQR8	Staphylococcus_phage	3.4e-23	29.9
WP_004185897.1\|2342238_2342985_+	GntR family transcriptional regulator	NA	NA	NA	NA
WP_004197492.1\|2343700_2345062_+	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_004185818.1\|2345601_2347041_+	multidrug transporter subunit MdtD	NA	NA	NA	NA
WP_162473466.1\|2347412_2347700_-	hypothetical protein	NA	NA	NA	NA
WP_004200476.1\|2347683_2348958_+	EAL domain-containing protein	NA	NA	NA	NA
WP_004185918.1\|2349089_2349695_-	class I SAM-dependent methyltransferase	NA	NA	NA	NA
WP_004186428.1\|2350218_2351241_-	2-dehydropantoate 2-reductase	NA	NA	NA	NA
WP_004185585.1\|2351256_2351784_-	DUF962 domain-containing protein	NA	NA	NA	NA
WP_004185910.1\|2351868_2352624_+	Crp/Fnr family transcriptional regulator	NA	NA	NA	NA
WP_004186611.1\|2352857_2354063_+	chromate efflux transporter	NA	NA	NA	NA
WP_096325460.1\|2354151_2355272_-\|transposase	IS3 family transposase	S5WIU1	Leptospira_phage	3.6e-49	39.5
WP_004185841.1\|2356334_2356913_-	superoxide dismutase [Fe]	Q56AR7	Bacillus_thuringiensis_phage	1.1e-44	44.7
WP_004197496.1\|2357109_2358492_-	exodeoxyribonuclease VII large subunit	A0A1B3AYB4	Gordonia_phage	6.1e-30	27.5
WP_004200482.1\|2358486_2358717_+	hypothetical protein	NA	NA	NA	NA
WP_004196455.1\|2359959_2360166_+	Trm112 family protein	NA	NA	NA	NA
WP_004185994.1\|2360339_2361131_+	3-deoxy-manno-octulosonate cytidylyltransferase	NA	NA	NA	NA
WP_004185840.1\|2361339_2362002_+	adenylate kinase	NA	NA	NA	NA
WP_004191998.1\|2362116_2363580_+\|transposase	IS1182-like element ISBma2 family transposase	A0A1X9I5T2	Streptococcus_phage	8.8e-80	38.6
WP_004196460.1\|2363683_2363887_-	cold-shock protein	A0A2H4N7Y6	Lake_Baikal_phage	6.8e-23	81.8
WP_004194131.1\|2364419_2364734_+\|protease	ATP-dependent Clp protease adapter ClpS	A0A218MMY6	uncultured_virus	4.4e-13	44.6

DBSCAN-SWA_8

2414880 : 2424117

unidentified_phage(16.67%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_004194112.1\|2414880_2416428_+	polynucleotide adenylyltransferase PcnB	H7BUW3	unidentified_phage	4.3e-24	31.2
WP_004194373.1\|2416464_2416992_+	2-amino-4-hydroxy-6- hydroxymethyldihydropteridine diphosphokinase	NA	NA	NA	NA
WP_004194274.1\|2416988_2417672_+	deoxynucleoside kinase	A0A249XZR7	Enterococcus_phage	2.6e-05	26.0
WP_004194137.1\|2417736_2418552_+	3-methyl-2-oxobutanoate hydroxymethyltransferase	A0A0N7HVJ8	Ostreococcus_lucimarinus_virus	8.8e-37	33.3
WP_004194350.1\|2418727_2420734_-	bifunctional anthranilate synthase component I family protein/class IV aminotransferase	S4VT78	Pandoravirus	9.7e-53	35.0
WP_004194374.1\|2420767_2421898_-	molecular chaperone DnaJ	A0A1V0SBY2	Catovirus	2.9e-22	27.6
WP_004194034.1\|2422164_2424117_-	molecular chaperone DnaK	A0A1V0SH73	Hokovirus	2.7e-148	49.2

DBSCAN-SWA_9

2737050 : 2791373

Burkholderia_phage(16.67%)

portal,transposase,protease,terminase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_004198091.1\|2737050_2738271_-\|transposase	ISL3-like element ISBma1 family transposase	A9YX10	Burkholderia_phage	2.3e-238	99.3
WP_004198364.1\|2738424_2742663_-	DNA-directed RNA polymerase subunit beta'	A0A2I7QNZ7	Vibrio_phage	2.3e-72	27.9
WP_004198365.1\|2742684_2746791_-	DNA-directed RNA polymerase subunit beta	E3T4Z4	Cafeteria_roenbergensis_virus	4.6e-25	21.4
WP_004198366.1\|2747154_2747529_-	50S ribosomal protein L7/L12	NA	NA	NA	NA
WP_004199864.1\|2747592_2748090_-	50S ribosomal protein L10	NA	NA	NA	NA
WP_004185135.1\|2748387_2749086_-	50S ribosomal protein L1	NA	NA	NA	NA
WP_004198368.1\|2749086_2749518_-	50S ribosomal protein L11	NA	NA	NA	NA
WP_004198369.1\|2749663_2750221_-	transcription termination/antitermination protein NusG	NA	NA	NA	NA
WP_004185179.1\|2750222_2750603_-	preprotein translocase subunit SecE	NA	NA	NA	NA
WP_004198356.1\|2750780_2751971_-	elongation factor Tu	A0A1V0SLW6	Klosneuvirus	1.5e-13	27.9
WP_096325434.1\|2752921_2754041_+\|transposase	IS3 family transposase	S5WIU1	Leptospira_phage	3.6e-49	39.5
WP_004198375.1\|2754445_2755582_-	DUF1700 domain-containing protein	NA	NA	NA	NA
WP_004198376.1\|2755578_2755920_-	PadR family transcriptional regulator	NA	NA	NA	NA
WP_073699081.1\|2756234_2756606_+	hypothetical protein	NA	NA	NA	NA
WP_004198377.1\|2756647_2758297_+	GMC family oxidoreductase N-terminal domain-containing protein	A0A1V0SI18	Klosneuvirus	2.0e-56	30.9
WP_004198379.1\|2758381_2759179_+	SDR family oxidoreductase	A0A2N9QUX2	Trichoplusia_ni_ascovirus	3.3e-12	28.8
WP_004198380.1\|2759224_2760034_+	molybdenum cofactor biosynthesis F family protein	NA	NA	NA	NA
WP_004198382.1\|2760044_2760437_+	nuclear transport factor 2 family protein	NA	NA	NA	NA
WP_004198383.1\|2760492_2761998_+	aldehyde dehydrogenase family protein	NA	NA	NA	NA
WP_004197126.1\|2762214_2763474_+	ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_004197127.1\|2763478_2764357_+	branched-chain amino acid ABC transporter permease	NA	NA	NA	NA
WP_004197128.1\|2764353_2765403_+	branched-chain amino acid ABC transporter permease	NA	NA	NA	NA
WP_004197129.1\|2765399_2766122_+	ATP-binding cassette domain-containing protein	A0A2H4PQG7	Staphylococcus_phage	3.8e-07	25.5
WP_004538585.1\|2766494_2767226_+	ATP-binding cassette domain-containing protein	W8CYL7	Bacillus_phage	1.6e-05	25.3
WP_004199873.1\|2767348_2768308_-	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_004197133.1\|2768707_2769808_-	porin	NA	NA	NA	NA
WP_004197137.1\|2770345_2773375_-	DEAD/DEAH box helicase family protein	A0A2K5B256	Erysipelothrix_phage	2.2e-181	38.7
WP_004197139.1\|2773415_2775431_-	site-specific DNA-methyltransferase	A0A2K5B2C1	Erysipelothrix_phage	3.3e-85	33.5
WP_004197145.1\|2775903_2777064_-	porin	NA	NA	NA	NA
WP_004197150.1\|2777363_2778041_-	response regulator	NA	NA	NA	NA
WP_004197153.1\|2778051_2779431_-	sensor histidine kinase	NA	NA	NA	NA
WP_004201276.1\|2779508_2780357_-	ABC transporter permease	NA	NA	NA	NA
WP_004199877.1\|2780384_2781182_-	ABC transporter ATP-binding protein	G3M9Y6	Bacillus_virus	3.5e-30	35.3
WP_004199878.1\|2781265_2782279_-	ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_004199879.1\|2782436_2782958_-	DUF2938 domain-containing protein	NA	NA	NA	NA
WP_004199880.1\|2782950_2783826_-	class I SAM-dependent methyltransferase	NA	NA	NA	NA
WP_004199881.1\|2783907_2784336_+	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_004201278.1\|2784655_2785438_-	flagellar biosynthetic protein FliR	NA	NA	NA	NA
WP_004199882.1\|2785556_2785829_-	flagellar biosynthesis protein FliQ	NA	NA	NA	NA
WP_038802950.1\|2786453_2787574_-\|transposase	IS3 family transposase	S5WIU1	Leptospira_phage	3.6e-49	39.5
WP_004199884.1\|2788381_2788678_+	type II toxin-antitoxin system RelE/ParE family toxin	A4JWV2	Burkholderia_virus	2.8e-49	98.0
WP_004202809.1\|2788680_2789037_+	putative addiction module antidote protein	A4JWV1	Burkholderia_virus	3.9e-42	100.0
WP_004199886.1\|2789080_2790136_-\|portal	phage portal protein	K4NZV0	Burkholderia_phage	5.7e-206	99.4
WP_004199888.1\|2790132_2790630_-\|terminase	terminase	K4NXI4	Burkholderia_phage	2.6e-55	100.0
WP_004199890.1\|2790851_2791373_-\|protease	ClpXP protease specificity-enhancing factor	A0A1S5R3H3	Pseudomonas_phage	1.9e-21	51.0

DBSCAN-SWA_10

2830587 : 2890156

Streptococcus_phage(33.33%)

transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_004196743.1\|2830587_2831301_-\|transposase	transposase	NA	NA	NA	NA
WP_004199949.1\|2831493_2832225_+	OmpW family protein	NA	NA	NA	NA
WP_004196745.1\|2832370_2833132_-	glycerophosphodiester phosphodiesterase	M1HTS7	Paramecium_bursaria_Chlorella_virus	2.8e-13	27.0
WP_004196746.1\|2833176_2834259_-	sn-glycerol-3-phosphate import ATP-binding protein UgpC	G9BWD6	Planktothrix_phage	9.6e-23	34.4
WP_004196747.1\|2834284_2835130_-	sn-glycerol-3-phosphate ABC transporter permease UgpE	NA	NA	NA	NA
WP_004196748.1\|2835126_2836011_-	sn-glycerol-3-phosphate ABC transporter permease UgpA	NA	NA	NA	NA
WP_004196749.1\|2836141_2837467_-	sn-glycerol-3-phosphate ABC transporter substrate-binding protein UgpB	NA	NA	NA	NA
WP_004196750.1\|2837551_2838784_-	deoxyguanosinetriphosphate triphosphohydrolase	NA	NA	NA	NA
WP_004196751.1\|2838832_2839912_-	3-dehydroquinate synthase	NA	NA	NA	NA
WP_004535019.1\|2839908_2840463_-	shikimate kinase	NA	NA	NA	NA
WP_162473472.1\|2840543_2842271_-	type IV pilus secretin PilQ	NA	NA	NA	NA
WP_004196756.1\|2842267_2843161_-	hypothetical protein	NA	NA	NA	NA
WP_011204157.1\|2843223_2843904_-	fimbrial protein	NA	NA	NA	NA
WP_004196759.1\|2843900_2844839_-	hypothetical protein	NA	NA	NA	NA
WP_004535017.1\|2845079_2847473_+	penicillin-binding protein 1A	NA	NA	NA	NA
WP_004191998.1\|2847573_2849037_-\|transposase	IS1182-like element ISBma2 family transposase	A0A1X9I5T2	Streptococcus_phage	8.8e-80	38.6
WP_004196764.1\|2849183_2849510_-	iron donor protein CyaY	NA	NA	NA	NA
WP_004545632.1\|2849546_2849831_+	lipoprotein	NA	NA	NA	NA
WP_004196768.1\|2849841_2851113_+	diaminopimelate decarboxylase	NA	NA	NA	NA
WP_004527905.1\|2851371_2852097_-	protein-methionine-sulfoxide reductase heme-binding subunit MsrQ	NA	NA	NA	NA
WP_004196774.1\|2852106_2853102_-	protein-methionine-sulfoxide reductase catalytic subunit MsrP	NA	NA	NA	NA
WP_038802950.1\|2853201_2854322_-\|transposase	IS3 family transposase	S5WIU1	Leptospira_phage	3.6e-49	39.5
WP_004196779.1\|2854387_2854672_-	hypothetical protein	NA	NA	NA	NA
WP_004196781.1\|2854673_2855339_-	flagellar biosynthetic protein FliO	NA	NA	NA	NA
WP_004184995.1\|2855335_2855833_-	flagellar motor switch protein FliN	NA	NA	NA	NA
WP_004196784.1\|2855825_2856824_-	flagellar motor switch protein FliM	NA	NA	NA	NA
WP_004196785.1\|2856846_2857344_-	flagellar basal body-associated protein FliL	NA	NA	NA	NA
WP_004196788.1\|2858180_2858903_-	murein hydrolase effector protein LrgB	NA	NA	NA	NA
WP_004199963.1\|2858971_2859442_-	CidA/LrgA family protein	NA	NA	NA	NA
WP_004196791.1\|2859581_2860505_+	LysR family transcriptional regulator	NA	NA	NA	NA
WP_004196792.1\|2860564_2862127_-	DHA2 family efflux MFS transporter permease subunit	NA	NA	NA	NA
WP_004196793.1\|2862274_2862772_-	MarR family transcriptional regulator	NA	NA	NA	NA
WP_004185228.1\|2862964_2863246_+	hypothetical protein	NA	NA	NA	NA
WP_004196794.1\|2863467_2865084_+	efflux transporter outer membrane subunit	NA	NA	NA	NA
WP_004196795.1\|2865454_2866246_-	type II secretion system protein N	NA	NA	NA	NA
WP_004196796.1\|2866284_2866791_-	type II secretion system protein M	NA	NA	NA	NA
WP_004202880.1\|2866787_2868218_-	type II secretion system protein GspL	NA	NA	NA	NA
WP_004553719.1\|2868242_2869313_-	type II secretion system minor pseudopilin GspK	NA	NA	NA	NA
WP_004185018.1\|2869494_2870223_-	prepilin-type N-terminal cleavage/methylation domain-containing protein	NA	NA	NA	NA
WP_004196806.1\|2870200_2870611_-	type II secretion system minor pseudopilin GspI	NA	NA	NA	NA
WP_004196808.1\|2870607_2871207_-	GspH/FimT family pseudopilin	NA	NA	NA	NA
WP_004196811.1\|2871241_2871694_-	type II secretion system major pseudopilin GspG	NA	NA	NA	NA
WP_004196816.1\|2871841_2872252_+	general secretion pathway protein GspC	NA	NA	NA	NA
WP_004196821.1\|2872323_2873541_-	type II secretion system inner membrane protein GspF	NA	NA	NA	NA
WP_004196824.1\|2873545_2875039_-	type II secretion system ATPase GspE	NA	NA	NA	NA
WP_004196826.1\|2875035_2877309_-	type II secretion system secretin GspD	NA	NA	NA	NA
WP_004196829.1\|2877715_2878174_+	lytic transglycosylase domain-containing protein	A0A0A8J856	Ralstonia_phage	8.8e-10	43.2
WP_004196834.1\|2878492_2879833_+	GTP-binding protein	NA	NA	NA	NA
WP_004191998.1\|2879968_2881432_-\|transposase	IS1182-like element ISBma2 family transposase	A0A1X9I5T2	Streptococcus_phage	8.8e-80	38.6
WP_004196837.1\|2881538_2881742_-	cold-shock protein	A0A2H4N7Y6	Lake_Baikal_phage	6.3e-21	73.1
WP_038802950.1\|2882061_2883181_+\|transposase	IS3 family transposase	S5WIU1	Leptospira_phage	3.6e-49	39.5
WP_004196846.1\|2883407_2883605_-	hypothetical protein	NA	NA	NA	NA
WP_004196848.1\|2883627_2885034_+	amino acid permease	NA	NA	NA	NA
WP_004196851.1\|2885347_2885713_-	c-type cytochrome	NA	NA	NA	NA
WP_004196853.1\|2885709_2886510_-	BON domain-containing protein	NA	NA	NA	NA
WP_004196857.1\|2886528_2887107_-	SIS domain-containing protein	NA	NA	NA	NA
WP_004196859.1\|2887229_2887664_-	YraN family protein	NA	NA	NA	NA
WP_004196861.1\|2887710_2888598_+	16S rRNA (cytidine(1402)-2'-O)-methyltransferase	NA	NA	NA	NA
WP_004191998.1\|2888692_2890156_+\|transposase	IS1182-like element ISBma2 family transposase	A0A1X9I5T2	Streptococcus_phage	8.8e-80	38.6

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. NC_006349

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection

2. NC_006348

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Click the colored protein region to show detailed information

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection