CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NC_008253	Escherichia coli 536, complete sequence	7 crisprs	cas14j,DinG,cas3,DEDDh,csa3,RT,PD-DExK,WYL	0	6	4	0

Results visualization

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CRISPR-Cas detection and classification

Crispr_ID: NC_008253_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_008253_1

422427-422562

Orphan

Consensus_repeat	Method
GCCGGATGCGGCGTGAACGCCTTATCCGGCCTACGAATGGCGC	CRISPRCasFinder

1 spacers

The CRISPR arrays of NC_008253_1

>merge|NC_008253|1|422427-422562|CRISPRCasFinder
GCCGGATGCGGCGTGAACGCCTTATCCGGCCTACGAATGGCGCGGAAATCTGTAGGCCTGATAAGCGTGGCGCTTCAGGCATTGGCCACCACAGCCGGATGCGGCGTGAACGCCTTATCCGGCCTACGAGTGGCGC

>NC_008253|1|1|422427-422562|CRISPRCasFinder
GCCGGATGCGGCGTGAACGCCTTATCCGGCCTACGAATGGCGC	GGAAATCTGTAGGCCTGATAAGCGTGGCGCTTCAGGCATTGGCCACCACA
GCCGGATGCGGCGTGAACGCCTTATCCGGCCTACGAGTGGCGC

Protein	Signature genes	Signature genes Name	Protein_function
NC_008253.1\|WP_001298553.1\|418584_419448_+\|DUF2877-domain-containing-protein	unknown	unknown	gnl\|CDD\|378658
NC_008253.1\|WP_000111853.1\|419437_420985_+\|acyl-CoA-synthetase-FdrA	unknown	unknown	gnl\|CDD\|180395
NC_008253.1\|WP_000691951.1\|428120_428396_+\|DUF1471-domain-containing-protein	unknown	unknown	gnl\|CDD\|182151
NC_008253.1\|WP_000052198.1\|430321_431212_+\|methylisocitrate-lyase	unknown	unknown	gnl\|CDD\|183086
NC_008253.1\|WP_000662396.1\|423609_424992_+\|amidohydrolase-family-protein	unknown	unknown	gnl\|CDD\|235873
NC_008253.1\|WP_000089053.1\|409919_411392_-\|betaine-aldehyde-dehydrogenase	unknown	unknown	gnl\|CDD\|183918
NC_008253.1\|WP_001084388.1\|416160_417093_-\|LysR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|182237
NC_008253.1\|WP_000976979.1\|427299_427974_-\|LysE-family-transporter	unknown	unknown	gnl\|CDD\|273358
NC_008253.1\|WP_000941011.1\|428496_430083_-\|propionate-catabolism-operon-regulatory-protein-PrpR	unknown	unknown	gnl\|CDD\|237963
NC_008253.1\|WP_000131027.1\|412121_414155_+\|choline-BCCT-transporter-BetT	unknown	unknown	gnl\|CDD\|236635
NC_008253.1\|WP_001298544.1\|411405_411993_-\|transcriptional-regulator-BetI	unknown	unknown	gnl\|CDD\|179115
NC_008253.1\|WP_001295808.1\|415030_416119_+\|DNA-binding-transcriptional-activator/c-di-GMP-phosphodiesterase-PdeL	unknown	unknown	gnl\|CDD\|214491
NC_008253.1\|WP_000116026.1\|432574_434026_+\|2-methylcitrate-dehydratase	unknown	unknown	gnl\|CDD\|181845
NC_008253.1\|WP_000010261.1\|434065_435952_+\|propionate--CoA-ligase	unknown	unknown	gnl\|CDD\|182517
NC_008253.1\|WP_001013871.1\|417184_417682_-\|DUF1097-domain-containing-protein	unknown	unknown	gnl\|CDD\|368942
NC_008253.1\|WP_001285909.1\|431371_432541_+\|2-methylcitrate-synthase	unknown	unknown	gnl\|CDD\|183463
NC_008253.1\|WP_000083477.1\|420984_422403_+\|DUF1116-domain-containing-protein	unknown	unknown	gnl\|CDD\|377673
NC_008253.1\|WP_000661659.1\|422649_423600_+\|carbamate-kinase-family-protein	unknown	unknown	gnl\|CDD\|183464
NC_008253.1\|WP_000692732.1\|425368_426418_+\|NADPH-dependent-aldehyde-reductase-YahK	unknown	unknown	gnl\|CDD\|176186
NC_008253.1\|WP_000153091.1\|417939_418545_+\|ankyrin-repeat-domain-containing-protein	unknown	unknown	gnl\|CDD\|293786

Protein	Function_ID	Function_description	E-value
NC_008253.1\|WP_001298553.1\|418584_419448_+\|DUF2877-domain-containing-protein	gnl\|CDD\|378658	pfam11392, DUF2877, Protein of unknown function (DUF2877). This bacterial family of proteins are putative carboxylase proteins however this cannot be confirmed.	1.6644e-35
NC_008253.1\|WP_000111853.1\|419437_420985_+\|acyl-CoA-synthetase-FdrA	gnl\|CDD\|180395	PRK06091, PRK06091, membrane protein FdrA; Validated.	5.04071e-161
NC_008253.1\|WP_000691951.1\|428120_428396_+\|DUF1471-domain-containing-protein	gnl\|CDD\|182151	PRK09929, PRK09929, hypothetical protein; Provisional.	5.05349e-43
NC_008253.1\|WP_000052198.1\|430321_431212_+\|methylisocitrate-lyase	gnl\|CDD\|183086	PRK11320, prpB, 2-methylisocitrate lyase; Provisional.	0
NC_008253.1\|WP_000662396.1\|423609_424992_+\|amidohydrolase-family-protein	gnl\|CDD\|235873	PRK06846, PRK06846, putative deaminase; Validated.	0
NC_008253.1\|WP_000089053.1\|409919_411392_-\|betaine-aldehyde-dehydrogenase	gnl\|CDD\|183918	PRK13252, PRK13252, betaine aldehyde dehydrogenase; Provisional.	0
NC_008253.1\|WP_001084388.1\|416160_417093_-\|LysR-family-transcriptional-regulator	gnl\|CDD\|182237	PRK10094, PRK10094, HTH-type transcriptional activator AllS.	7.71252e-82
NC_008253.1\|WP_000976979.1\|427299_427974_-\|LysE-family-transporter	gnl\|CDD\|273358	TIGR00949, Uncharacterized_membrane_protein_YahN, The Resistance to Homoserine/Threonine (RhtB) Family protein. [Transport and binding proteins, Amino acids, peptides and amines].	8.68624e-75
NC_008253.1\|WP_000941011.1\|428496_430083_-\|propionate-catabolism-operon-regulatory-protein-PrpR	gnl\|CDD\|237963	PRK15424, PRK15424, propionate catabolism operon regulatory protein PrpR; Provisional.	0
NC_008253.1\|WP_000131027.1\|412121_414155_+\|choline-BCCT-transporter-BetT	gnl\|CDD\|236635	PRK09928, PRK09928, choline transport protein BetT; Provisional.	0
NC_008253.1\|WP_001298544.1\|411405_411993_-\|transcriptional-regulator-BetI	gnl\|CDD\|179115	PRK00767, PRK00767, transcriptional regulator BetI; Validated.	3.76664e-110
NC_008253.1\|WP_001295808.1\|415030_416119_+\|DNA-binding-transcriptional-activator/c-di-GMP-phosphodiesterase-PdeL	gnl\|CDD\|214491	smart00052, EAL, Putative diguanylate phosphodiesterase. Putative diguanylate phosphodiesterase, present in a variety of bacteria.	9.73401e-102
NC_008253.1\|WP_000116026.1\|432574_434026_+\|2-methylcitrate-dehydratase	gnl\|CDD\|181845	PRK09425, prpD, bifunctional 2-methylcitrate dehydratase/aconitate hydratase.	0
NC_008253.1\|WP_000010261.1\|434065_435952_+\|propionate--CoA-ligase	gnl\|CDD\|182517	PRK10524, prpE, propionyl-CoA synthetase; Provisional.	0
NC_008253.1\|WP_001013871.1\|417184_417682_-\|DUF1097-domain-containing-protein	gnl\|CDD\|368942	pfam06496, DUF1097, Protein of unknown function (DUF1097). This family consists of several bacterial putative membrane proteins.	2.01468e-18
NC_008253.1\|WP_001285909.1\|431371_432541_+\|2-methylcitrate-synthase	gnl\|CDD\|183463	PRK12351, PRK12351, methylcitrate synthase; Provisional.	0
NC_008253.1\|WP_000083477.1\|420984_422403_+\|DUF1116-domain-containing-protein	gnl\|CDD\|377673	pfam06545, DUF1116, Protein of unknown function (DUF1116). This family contains hypothetical bacterial proteins of unknown function.	1.43271e-115
NC_008253.1\|WP_000661659.1\|422649_423600_+\|carbamate-kinase-family-protein	gnl\|CDD\|183464	PRK12352, PRK12352, putative carbamate kinase; Reviewed.	0
NC_008253.1\|WP_000692732.1\|425368_426418_+\|NADPH-dependent-aldehyde-reductase-YahK	gnl\|CDD\|176186	cd05283, CAD1, Cinnamyl alcohol dehydrogenases (CAD). Cinnamyl alcohol dehydrogenases (CAD), members of the medium chain dehydrogenase/reductase family, reduce cinnamaldehydes to cinnamyl alcohols in the last step of monolignal metabolism in plant cells walls. CAD binds 2 zinc ions and is NADPH- dependent. CAD family members are also found in non-plant species, e.g. in yeast where they have an aldehyde reductase activity. The medium chain dehydrogenases/reductase (MDR)/zinc-dependent alcohol dehydrogenase-like family, which contains the zinc-dependent alcohol dehydrogenase (ADH-Zn) and related proteins, is a diverse group of proteins related to the first identified member, class I mammalian ADH. MDRs display a broad range of activities and are distinguished from the smaller short chain dehydrogenases (~ 250 amino acids vs. the ~ 350 amino acids of the MDR). The MDR proteins have 2 domains: a C-terminal NAD(P) binding-Rossmann fold domain of a beta-alpha form and an N-terminal catalytic domain with distant homology to GroES. The MDR group contains a host of activities, including the founding alcohol dehydrogenase (ADH), quinone reductase, sorbitol dehydrogenase, formaldehyde dehydrogenase, butanediol DH, ketose reductase, cinnamyl reductase, and numerous others. The zinc-dependent alcohol dehydrogenases (ADHs) catalyze the NAD(P)(H)-dependent interconversion of alcohols to aldehydes or ketones. Active site zinc has a catalytic role, while structural zinc aids in stability. ADH-like proteins typically form dimers (typically higher plants, mammals) or tetramers (yeast, bacteria), and generally have 2 tightly bound zinc atoms per subunit. The active site zinc is coordinated by a histidine, two cysteines, and a water molecule. The second zinc seems to play a structural role, affects subunit interactions, and is typically coordinated by 4 cysteines.	0
NC_008253.1\|WP_000153091.1\|417939_418545_+\|ankyrin-repeat-domain-containing-protein	gnl\|CDD\|293786	sd00045, ANK, ankyrin repeats. Ankyrin repeats are one of the most abundant repeat motifs, and generally function as scaffolds for protein-protein interactions in processes including cell cycle, transcriptional regulation, signal transduction, vesicular trafficking, and inflammatory response. Although predominantly found in eukaryotic proteins, they are also found in some bacterial and viral proteins. Less is known of their physiological roles in prokaryotes. Some bacterial ANK proteins play key roles in microbial pathogenesis by mimicking or manipulating host function(s). The pathogen Providencia alcalifaciens N-formyltransferase ankyrin repeats function in small molecule binding and allosteric control. Ankyrin-repeat proteins have been associated with a number of human diseases.	1.75537e-19

>NC_008253.1|WP_000083477.1|420984_422403_+|DUF1116-domain-containing-protein
MSQSLFSQPLNVINVGIAMFSDDLKKQHVEVTQLDWTPPGQGNMQVVQALDNIADSPLADKITAANQQALERIIQSHPVLIGFDQAINVVPGMTPKTILHAGPPVTWEKMCGAMKGAVTGALVFEGLAKDLDEAAELAASGEITFSPCHEHDCVGSMAGVTSASMFMHIVKNKTYGNVAYTNMSEQMAKILRMGANDQSVIDRLNWMRDVQGPMLRDAMKIIGEIDLRLMLAQALHMGDECHNRNNAGTTLLIQALTPGIIQAGYSVEQQREVFEFVASSDYFSGPTWMAMCKAAMDAAHGIEYSTVVTTMARNGVEFGLRVSGLPGQWFTGPAQQVIGPMFAGYKPEDSGLDIGDSAITETYGIGGFAMATAPAIVALVGGTVEEAIDFSRQMREITLGENPNVTIPLLGFMGVPSAIDITRVGSSGILPVINTAIAHKDAGVGMIGAGIVHPPFACFEKAIFGWCERYGV
>NC_008253.1|WP_000111853.1|419437_420985_+|acyl-CoA-synthetase-FdrA
MSVKIVIKPNTYFDSVSLMSISTRANKLDGVEQAFVAMATEMNKGVLKNLGLLTPELEQAKNGDLMIVINGKSGVDNEQLLAEIEELFNTKAQSGSHEARYATIASAKKYIPESNLAVISVNGLFAAREARQALQNDLNVMLFSDNVSVEDELALKQLAHEKGLLMMGPDCGTAIINGAALCFGNAVRRGNIGIVGASGTGSQELSVRIHEFGGGVSQLIGTGGRDLSEKIGGLMMLDAIGMLENDPQTEIIVLISKPPAPAVARKVLERARACRKPVVACFLGRGETSVDEQGLQFARGSKEAALKAVMLSGVKQEHLDLHTLNQPLIADVRARLQPQQKYIRGLFCGGTLCDETLFAVMEKHGDVYSNIQPDPEFRLQDINRSIKHTFLDFGDDDFTNGKPHPMIDPTNRISRLIEEARDPEVAVIVMDFVLGFGSHEDPVGSTIEAIKEAKAIAAAEGRELIILAYVLGTDLDTPSLEQQSQMLLDAGVILASSSTNTGLLAREFICKGEEA
>NC_008253.1|WP_001298553.1|418584_419448_+|DUF2877-domain-containing-protein
MWALTADADFLAQRGQGQVEQVFARAVNIALPARQQLLTLLCEEYDNAPNSCRLALTHFNGLFRHGDKVQFDDQGITVGQHLHIEMSHCQRWLSPTLQMTALNFHLIAWQQWHDIIHQHLGENETLFNYRGDNPFYQALNKELHIKRRAVIQAVNDKQNIASAVASMMGLGIGLTPSADDYLTGLVLILFISGHPAEKYKEEFYRGLQRGRNNTTLLSAITLEAALQQRCRENIHRFIHNIIYDIPGNATQAIEKIKHIGSSSGCDMLYGMADGCALSQTYGGNYVS
>NC_008253.1|WP_000153091.1|417939_418545_+|ankyrin-repeat-domain-containing-protein
MTIKNLPADYLLAAQQGDIDKVKNCLALGVDINTCDRHGKTAITLASLYQQYACVQALIDAGADINKQDHTCLNPFLISCLNDDLTLLRIILPAKPDLNCVTRFGGVGLTPACEKGHLSIVKELLANTEINVNQTNHVGWTPLLEAIVLNDGGIKQQAIVQLLLEHGASPHLTDKYGKTPLELARERGFEEIAQLLIAAGA
>NC_008253.1|WP_001013871.1|417184_417682_-|DUF1097-domain-containing-protein
MNGLTATGVTVGICAGLWQLVSSHVGLSQGWELLGTIGFVAFCSFYAAGGGKSGFIKSLAVNYSGMVWAFFAALAAGWLAPVSGLSAFWASVITTVPFSAVVVWQGRFWLLSFIPGGFLGMTLFFASGMNWTVTLLGFLAGNCVGIISEYGGQKLSEATTKSDGY
>NC_008253.1|WP_001084388.1|416160_417093_-|LysR-family-transcriptional-regulator
MNSIFTEENLLAFTTAARFGSFSKAAEELGLTTSAISYTIKRMETGLDVVLFTRSTRSIELTESGRYFFRKATDLLNDFHAIKRSIDTISQGIEARVRICINQLLYTPKHTARLLQVLKKQFPTCQITVTTEVYNGVWDAIINNQANIAIGAPDTLLDGGGIDYTEIGAIRWAFAIAPDHPLAFVPEPIAESQLRLYPNIMVEDTAHTINKKVGWLLHGQESILVPDFNTKCQCQILGEGIGFLPDYMVREAMAQSLLVTRQIHNPRQDSRMLLATQHSATGQVTQWIKKQFAPNGILTGIYQDLLHREN
>NC_008253.1|WP_001295808.1|415030_416119_+|DNA-binding-transcriptional-activator/c-di-GMP-phosphodiesterase-PdeL
MNSCDFRVFLQEFGTTVHLSLPGSVSEKERLLLKLLMQGMSVTEISQYRNRSAKTISHQKKQLFEKLGIQSDITFWRDIFFQYNPEIISATGNNSHKYINDNHYHHIVTPEAISLALENHEFKPWIQPVFCAQTGVLTGCEVLVRWEHPQTGMIPPDQFIPLAESSGLIVIMTRQLMKQTADILMPVKHLLPDNFHIGINVSAGCFLAAGFEKECLNLVKKLGNDKIKLVLELTERNPIPVTPEARAIFDSLHQHNITFALDDFGTGYATYRYLQAFPVDFIKIDKSFVQMASVDEISGHIVDNIVELARKPGLSIVAEGVETQEQADLMIGKGVHFLQGYLYSPPVPGNKFISEWVMKAGG
>NC_008253.1|WP_000131027.1|412121_414155_+|choline-BCCT-transporter-BetT
MTDLSHSREKDKINPVVFYTSAGLILLFSLTTILFRDFSALWIGRTLDWVSKTFGWYYLLAATLYIVFVVCIACSRFGSVKLGPEQSKPEFSLLSWAAMLFAAGIGIDLMFFSVAEPITQYMQPPEGAGQTIEAARQAMVWTLFHYGLTGWSMYALMGMALGYFSYRYNLPLTIRSALYPIFGKRINGPIGHSVDIAAVIGTIFGIATTLGIGVVQLNYGLSVLFDIPDSMAAKAALIALSVIIATISVTSGVDKGIRVLSELNVALALGLILFVLFMGDTSFLLNALVLNVGDYVNRFMGMTLNSFAFDRPVEWMNNWTLFFWAWWVAWSPFVGLFLARISRGRTIRQFVLGTLIIPFTFTLLWLSVFGNSALYEIIHGGAAFAEEAMVHPERGFYSLLAQYPAFTFSASVATITGLLFYVTSADSGALVLGNFTSQLKDINSDAPGWLRVFWSVAIGLLTLGMLMTNGISALQNTTVIMGLPFSFVIFFVMAGLYKSLKVEDYRRESANRDTAPRPLGLQDRLSWKKRLSRLMNYPGTRYTKQMMETVCYPAMEEVAQELRLRGAYVELKNLPPEEGQQLGHLDLLVHMGEEQNFVYQIWPQQYSVPGFTYRARSGKSTYYRLETFLLEGSQGNDLMDYSKEQVITDILDQYERHLNFIHLHREAPGHSVMFPDA
>NC_008253.1|WP_001298544.1|411405_411993_-|transcriptional-regulator-BetI
MPKLGMQSIRRRQLIDATLEAINEVGMHDATIAQIARRAGVSTGIISHYFRDKNGLLEATMRDITSQLRDAVLNRLHALPQGSAELRLQAIVGGNFDETQVSSAAMKAWLAFWASSMHQPMLYRLQQVSSRRLLSNLVSEFRRELPRQQAQEAGYGLAALIDGLWLRAALSGKPLDKPLAHSLTRHFITQHLSTD
>NC_008253.1|WP_000089053.1|409919_411392_-|betaine-aldehyde-dehydrogenase
MSRMAEQQLYIHGGYTSATSGHTFETINPANGNVLATVQAAGREDVDRAVKSAQQGQKIWAAMTAMERSRILRRAVDILRERNDELAKLETLDTGKAYSETSTVDIVTGADVLEYYAGLIPSLEGSQIPLRETSFVYTRREPLGVVAGIGAWNYPIQIALWKSAPALAAGNAMIFKPSEVTPLTALKLAEIYSEAGLPDGVFNVLPGVGAETGQYLTEHPGIAKVSFTGGVASGKKVMANSAASSLKEVTMELGGKSPLIVFDDADLELAADIAMMANFFSSGQVCTNGTRVFVPAKCKAAFEQKILARVERIRADDVFDPQTNFGPLVSFPHRDNVLRYIAKGKEEGARVLCGGDVLKGDGFDNGAWVAPTVFTDCSDDMTIVREEIFGPVMSILIYESEDEVIRRANDTDYGLAAGIVTADLNRAHRVIHQLEAGICWINTWGESPAEMPVGGYKHSGIGRENGVMTLQSYTQVKSIQVEMAKFQSIF
>NC_008253.1|WP_000661659.1|422649_423600_+|carbamate-kinase-family-protein
MKELVVVAIGGNSIIKDNASQSIEHQAEAVKAVADTVLEMLASDYDIVLTHGNGPQVGLDLRRAEIAHEREGLPLTPLANCVADTQGGIGYLIQQALNNRLARHGEKKAVTVVTQVEVDKNDPGFAHPTKPIGEFFSESQRDELQKANPDWRFVEDAGRGYRRVVASPEPKRIVEAPAIKALIQQGFVVIGAGGGGIPVVRTEAGDYQSVDAVIDKDLSTALLAREIHADILVITTGVEKVCIHFGKPQQQALDRVDIATMTRYMQEGHFPPGSMLPKIIASLTFLEQGGKEVIITTPECLPAALRGETGTHIIKT
>NC_008253.1|WP_000662396.1|423609_424992_+|amidohydrolase-family-protein
MKENNSRREFLSQSGKMVTAAALFGPSVPLAHAGVAGTLNCEANNTMKITDPHYYLDNVLLETGFDYENGVAVQTRTARQTVEIQDGKIVALRENKQHPDATLPHYDAGGKLMLPTTRDMHIHLDKTFYGGPWRSLNRPAGTTIQDMIKLEQKMLPELQPYTQERAEKLIDLLQSKGTTIARSHCNIEPVSGLKNLQNLQAVLARRQAGFKCEIVAFPQHGLLLSKSESLMREAMQAGAHYVGGLDPTSVDGAMEKSLDTMFQIALDYDKGVDIHLHETTPAGVAAINYMVETVEKTPQLKGKLTISHAFALATLNEQQVDKLAHRMVAQQISIASTVPIGTLHMPLKQLHDKGVKVMTGTDSVIDHWSPYGLGDMLEKANLYAQLYIRPNEQNLSRSLFLATGDVLPLNEKGERVWPKAQDDASFVLVDASCSAEAVARISPRTATFHKGQLVWGSVAG
>NC_008253.1|WP_000692732.1|425368_426418_+|NADPH-dependent-aldehyde-reductase-YahK
MKIKAVGAYSAKQPLEPMDITRREPGPHDVKIEIAYCGVCHSDLHQVRSEWAGTVYPCVPGHEIVGRVVAVGDQVEKHAPGDLVGVGCIVDSCKHCEECEDGLENYCDYMTGTYNSPTPDEPGHTLGGYSQQIVVHERYVLRIRHPQEQLAAVAPLLCAGITTYSPLRHWQAGPGKKVGVVGIGGLGHMGIKLAHAMGAHVVAFTTSESKREAAKALGADEVVNSRNADEMVAHVKSFDFILNTVAAPHNLDDFTTLLKRDGTITLVGAPATPHKSPEVFNLIMKRRAIAGSMIGGIPETQEMLDFCAEHGIVADIEMIRADQINEAYERMLRGDVKYRFVIDNRTLTD
>NC_008253.1|WP_000976979.1|427299_427974_-|LysE-family-transporter
MMKLLHLFMDEITMDPLHAVYLTVGLFVITFFNPGANLFVVVQTSLASGRRAGVLTGLGVALGDAFYSGLGLFGLATLITQCEEIFSLIRIVGGAYLLWFAWCSSMRRHSTPQMSTLQQPISAPWYVFFRRGLITDLSNPQTVLFFISIFSVTLHAETPTWARLMAWAGIVLASIIWRVFLSQAFSLPAVRRAYGRMQRVASRVIGAIIGVFALRLIYEGVTQR
>NC_008253.1|WP_000691951.1|428120_428396_+|DUF1471-domain-containing-protein
MKIISKMLVGALAFAVTNVYAAELMTKAEFEKVASQYEKIGDISTSNEMSTADAKEDLIKKADEKGADVLVLTSGQTDNKIHGTANIYKKK
>NC_008253.1|WP_000941011.1|428496_430083_-|propionate-catabolism-operon-regulatory-protein-PrpR
MAHPPRLNDDKPVIWTVSVTRLFELFRDISLEFDHLANIPPIQLGFEKAVTYIRKKLASERCDAIIAAGSNGAYLKSRLSVPVILIKPSGYDLLQALAKAGKLTSSIGVVTYQETIPALVAFQKTFNLRLDQRSYITEEDARGQINELKANGTEAVVGAGLITDLAEEAGMTGIFIYSAATVRQAFSDALDMTRMSLRHNTHDATRNALRTRYVLGDMLGQSPQMEQVRQTILLYARSSAAVLIEGETGTGKELAAQAIHREYFARHDARQGKKSHPFVAVNCGAIAESLLEAELFGYEEGAFTGSRRGGRAGLFEIAHGGTLFLDEIGEMPLPLQTRLLRVLEEKEVTRVGGHQPVPVDVRVISATHCNLEEDMQQGQFRRDLFYRLSILRLQLPPLRERVADILPLAESFLKVSLAALSAPFAAALRQGLQASETMLVHYDWPGNIRELRNMMERLALFLSVESTPDLTPQFLQLLLPELARESAKTPIPGLLTAQQALEKFNGDKTAAANYLGISRTTFWRRLKS
>NC_008253.1|WP_000052198.1|430321_431212_+|methylisocitrate-lyase
MSLHSPGKAFRAALTKENPLQIVGTINANHALLAQRAGYQAIYLSGGGVAAGSLGLPDLGISTLDDVLTDIRRITDVCSLPLLVDADIGFGSSAFNVARTVKSMIKAGAAGLHIEDQVGAKRCGHRPNKAIVSKEEMVDRIRAAVDAKTDPDFVIMARTDALAVEGLDAAIERAQAYVEAGAEMLFPEAITELAMYRQFADAVQVPILANITEFGATPLFTTDELRSAHVAMALYPLSAFRAMNRAAEHVYNILRQEGTQKSVIDTMQTRNELYESINYYQYEEKLDDLFARGQVK
>NC_008253.1|WP_001285909.1|431371_432541_+|2-methylcitrate-synthase
MSDTTILQNSTHVIKPKKSVALSGVPAGNTALCTVGKSGNDLHYRGYDILDLAEHCEFEEVAHLLIHGKLPTRDELAAYKTKLKALRGLPANVRTVLEALPAASHPMDVMRTGVSALGCTLPEKEGHTVSGARDIADKLLASLSSILLYWYHYSHNGERIQPETDDDSIGGHFLHLLHGEKPSQSWEKAMHISLVLYAEHEFNASTFTSRVIAGTGSDMYSAIIGAIGALRGPKHGGANEVSLEIQQRYETPDEAEADIRKRVENKEVVIGFGHPVYTIADPRHQVIKRVAKQLSQEGGSLKMYNIADRLETVMWESKKMFPNLDWFSAVSYNMMGVPTEMFTPLFVIARVTGWAAHIIEQRQDNKIIRPSANYVGPEDRQFVALDKRQ
>NC_008253.1|WP_000116026.1|432574_434026_+|2-methylcitrate-dehydratase
MSVQINNIRPEFDREIVDIVDYVMNYEISSRVAYDTAHYCLLDTLGCGLEALEYPACKKLLGPIVPGTVVPNGVRVPGTQFQLDPVQAAFNIGAMIRWLDFNDTWLAAEWGHPSDNLGGILATADWLSRNAVASGKAPLTMKQVLTGMIKAHEIQGCIALENSFNRVGLDHVLLVKVASTAVVAEMLGLTREEILNAVSLAWVDGQSLRTYRHAPNTGTRKSWAAGDATSRAVRLALMAKTGEMGYPSALTAPVWGFYDVSFKGESFRFQRPYGSYVMENVLFKISFPAEFHSQTAVEAAMTLYEQMQAAGKTAADIEKVTIRTHEACIRIIDKKGPLNNPADRDHCIQYMVAIPLLFGRLTAADYEDNVAQDKRIDALREKINCFEDPAFTADYHDPEKRAIANAITLEFTDGTRFEEVVVEYPIGHTRRRQDGIPKLVEKFKINLARQFPTRQQQRILEVSLDRTRLEQMPVNEYLDLYVI
>NC_008253.1|WP_000010261.1|434065_435952_+|propionate--CoA-ligase
MSFSEFYQRSINEPEQFWAEQARRIDWQTPFTQTLDHSNPPFARWFCEGRTNLCHNAIDRWLEKQPEALALIAVSSETEEERTFTFRQLHDEVNAVASMLRSLGVQRGDRVLVYMPMIAEAHITLLACARIGAIHSVVFGGFASHSVAARIDDAKPVLIVSADAGARGGKIIPYKKLLDDAISQAQHQPRHVLLVDRGLAKMARVSGRDVDFASLRHQHIGARVPMAWLESNETSCILYTSGTTGKPKGVQRDVGGYAVALATSMDTIFGGKAGGVFFCASDIGWVVGHSYIVYAPLLAGMATIVYEGLPTWPDCGVWWKIVEKYQVSRMFSAPTAIRVLKKFPTAEIRKHDLSSLEVLYLAGEPLDEPTASWVSNTLDVPVIDNYWQTESGWPIMAIARGLDDRPTRLGSPGVPMYGYNVQLLNEVTGEPCGVNEKGMLVVEGPLPPGCIQTIWGDDDRFVKTYWSLFSRPVYATFDWGIRDADGYHFILGRTDDVINVAGHRLGTREIEESISSHPGVAEVAVVGVKDALKGQVAVAFVIPKESDSLEDREVAHLQEKAIMALVDSQIGNFGRPAHVWFVSQLPKTRSGKMLRRTIQAICEGRDPGDLTTIDDPASLDQIRQAMEE

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Crispr_ID: NC_008253_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_008253_2

777669-777810

Orphan

Consensus_repeat	Method
GCCGGATGCGGCGTGAACGCCTTATCCGGCCTACAAAAGAAATGCAG	CRISPRCasFinder

1 spacers

The CRISPR arrays of NC_008253_2

>merge|NC_008253|2|777669-777810|CRISPRCasFinder
GCCGGATGCGGCGTGAACGCCTTATCCGGCCTACAAAAGAAATGCAGAAACCGTAGGCCTGATAAGACGCGCAAGCGTCGCATCAGGTAAACAGCGCCGGATGCGGCGTGAATGCCTTATCCGGCCTACAAAAGAAATGCAG

>NC_008253|2|2|777669-777810|CRISPRCasFinder
GCCGGATGCGGCGTGAACGCCTTATCCGGCCTACAAAAGAAATGCAG	AAACCGTAGGCCTGATAAGACGCGCAAGCGTCGCATCAGGTAAACAGC
GCCGGATGCGGCGTGAATGCCTTATCCGGCCTACAAAAGAAATGCAG

Protein	Signature genes	Signature genes Name	Protein_function
NC_008253.1\|WP_001305582.1\|773890_773998_-\|hypothetical-protein	unknown	unknown	unknown
NC_008253.1\|WP_000099829.1\|780799_782017_+\|2-oxoglutarate-dehydrogenase-complex-dihydrolipoyllysine-residue-succinyltransferase	unknown	unknown	gnl\|CDD\|235571
NC_008253.1\|WP_000884361.1\|786830_788399_+\|cytochrome-ubiquinol-oxidase-subunit-I	unknown	unknown	gnl\|CDD\|185052
NC_008253.1\|WP_000785834.1\|772401_773685_-\|citrate-(Si)-synthase	unknown	unknown	gnl\|CDD\|180164
NC_008253.1\|WP_001144719.1\|770681_771728_-\|AbrB-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|225721
NC_008253.1\|WP_000538734.1\|784385_785501_+\|tetratricopeptide-repeat-protein	unknown	unknown	gnl\|CDD\|276809
NC_008253.1\|WP_000912741.1\|768201_769134_+\|5-oxoprolinase-subunit-PxpC	unknown	unknown	gnl\|CDD\|129807
NC_008253.1\|WP_001181473.1\|777983_780785_+\|2-oxoglutarate-dehydrogenase-E1-component	unknown	unknown	gnl\|CDD\|236499
NC_008253.1\|WP_000775540.1\|775123_776890_+\|succinate-dehydrogenase-flavoprotein-subunit	unknown	unknown	gnl\|CDD\|181594
NC_008253.1\|WP_000034602.1\|789681_789975_+\|cyd-operon-protein-YbgE	unknown	unknown	gnl\|CDD\|236721
NC_008253.1\|WP_001114006.1\|769893_770685_+\|endonuclease-VIII	unknown	unknown	gnl\|CDD\|182467
NC_008253.1\|WP_001098375.1\|790124_790529_+\|tol-pal-system-associated-acyl-CoA-thioesterase	unknown	unknown	gnl\|CDD\|182742
NC_008253.1\|WP_000687123.1\|769123_769858_+\|5-oxoprolinase-subunit-PxpA	unknown	unknown	gnl\|CDD\|212111
NC_008253.1\|WP_000270282.1\|789568_789682_+\|cytochrome-bd-I-oxidase-subunit-CydX	unknown	unknown	gnl\|CDD\|227227
NC_008253.1\|WP_001048602.1\|782110_783277_+\|ADP-forming-succinate--CoA-ligase-subunit-beta	unknown	unknown	gnl\|CDD\|234813
NC_008253.1\|WP_001235263.1\|776905_777622_+\|succinate-dehydrogenase-iron-sulfur-subunit-SdhB	unknown	unknown	gnl\|CDD\|235652
NC_008253.1\|WP_000025458.1\|783276_784146_+\|succinate--CoA-ligase-subunit-alpha	unknown	unknown	gnl\|CDD\|180194
NC_008253.1\|WP_000263355.1\|774378_774783_+\|succinate-dehydrogenase-cytochrome-b556-subunit	unknown	unknown	gnl\|CDD\|181900
NC_008253.1\|WP_000568275.1\|788414_789554_+\|cytochrome-d-ubiquinol-oxidase-subunit-II	unknown	unknown	gnl\|CDD\|184965
NC_008253.1\|WP_000254365.1\|774776_775124_+\|succinate-dehydrogenase-membrane-anchor-subunit	unknown	unknown	gnl\|CDD\|181901

Protein	Function_ID	Function_description	E-value
NC_008253.1\|WP_000538734.1\|784385_785501_+\|tetratricopeptide-repeat-protein	gnl\|CDD\|276809	sd00006, TPR, Tetratricopeptide repeat. The Tetratricopeptide repeat (TPR) typically contains 34 amino acids and is found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi, plants, and humans. It is present in a variety of proteins including those involved in chaperone, cell-cycle, transcription, and protein transport complexes. The number of TPR motifs varies among proteins. Those containing 5-6 tandem repeats generate a right-handed helical structure with an amphipathic channel that is thought to accommodate an alpha-helix of a target protein. It has been proposed that TPR proteins preferentially interact with WD-40 repeat proteins, but in many instances several TPR-proteins seem to aggregate to multi-protein complexes.	5.36055e-18
NC_008253.1\|WP_000099829.1\|780799_782017_+\|2-oxoglutarate-dehydrogenase-complex-dihydrolipoyllysine-residue-succinyltransferase	gnl\|CDD\|235571	PRK05704, PRK05704, 2-oxoglutarate dehydrogenase complex dihydrolipoyllysine-residue succinyltransferase.	0
NC_008253.1\|WP_000884361.1\|786830_788399_+\|cytochrome-ubiquinol-oxidase-subunit-I	gnl\|CDD\|185052	PRK15097, PRK15097, cytochrome bd-I ubiquinol oxidase subunit CydA.	0
NC_008253.1\|WP_000785834.1\|772401_773685_-\|citrate-(Si)-synthase	gnl\|CDD\|180164	PRK05614, gltA, citrate synthase.	0
NC_008253.1\|WP_001144719.1\|770681_771728_-\|AbrB-family-transcriptional-regulator	gnl\|CDD\|225721	COG3180, AbrB, Putative ammonia monooxygenase [General function prediction only].	8.43543e-109
NC_008253.1\|WP_000912741.1\|768201_769134_+\|5-oxoprolinase-subunit-PxpC	gnl\|CDD\|129807	TIGR00724, Uncharacterized_protein_HI_1730, biotin-dependent carboxylase uncharacterized domain. Urea amidolyase of Saccharomyces cerevisiae is a 1835 amino acid protein with an amidase domain, a biotin/lipoyl cofactor attachment domain, a carbamoyl-phosphate synthase L chain-like domain, and uncharacterized regions. It has both urea carboxylase and allophanate hydrolase activities. This model models a domain that represents uncharacterized prokaryotic proteins of about 300 amino acids, regions of prokaryotic urea carboxylase and of the urea carboxylase region of yeast urea amidolyase, and regions of other biotin-containing proteins. [Unknown function, General].	4.09729e-178
NC_008253.1\|WP_001181473.1\|777983_780785_+\|2-oxoglutarate-dehydrogenase-E1-component	gnl\|CDD\|236499	PRK09404, sucA, 2-oxoglutarate dehydrogenase E1 component; Reviewed.	0
NC_008253.1\|WP_000775540.1\|775123_776890_+\|succinate-dehydrogenase-flavoprotein-subunit	gnl\|CDD\|181594	PRK08958, sdhA, succinate dehydrogenase flavoprotein subunit; Reviewed.	0
NC_008253.1\|WP_000034602.1\|789681_789975_+\|cyd-operon-protein-YbgE	gnl\|CDD\|236721	PRK10588, PRK10588, hypothetical protein; Provisional.	9.30037e-57
NC_008253.1\|WP_001114006.1\|769893_770685_+\|endonuclease-VIII	gnl\|CDD\|182467	PRK10445, PRK10445, endonuclease VIII; Provisional.	0
NC_008253.1\|WP_001098375.1\|790124_790529_+\|tol-pal-system-associated-acyl-CoA-thioesterase	gnl\|CDD\|182742	PRK10800, PRK10800, acyl-CoA thioesterase YbgC; Provisional.	5.36047e-91
NC_008253.1\|WP_000687123.1\|769123_769858_+\|5-oxoprolinase-subunit-PxpA	gnl\|CDD\|212111	cd10800, LamB_YcsF_YbgL_like, Escherichia coli putative lactam utilization protein YbgL and similar proteins. This subfamily of the LamB/YbgL family is represented by the Escherichia coli putative lactam utilization protein YbgL. Although their molecular function of member of this subfamily is unknown, they show high sequence similarity to the Aspergillus nidulans lactam utilization protein LamB, which might be required for conversion of exogenous 2-pyrrolidinone to endogenous GABA.	1.93833e-141
NC_008253.1\|WP_000270282.1\|789568_789682_+\|cytochrome-bd-I-oxidase-subunit-CydX	gnl\|CDD\|227227	COG4890, COG4890, Predicted outer membrane lipoprotein [Function unknown].	4.51563e-12
NC_008253.1\|WP_001048602.1\|782110_783277_+\|ADP-forming-succinate--CoA-ligase-subunit-beta	gnl\|CDD\|234813	PRK00696, sucC, ADP-forming succinate--CoA ligase subunit beta.	0
NC_008253.1\|WP_001235263.1\|776905_777622_+\|succinate-dehydrogenase-iron-sulfur-subunit-SdhB	gnl\|CDD\|235652	PRK05950, sdhB, succinate dehydrogenase iron-sulfur subunit; Reviewed.	3.48257e-167
NC_008253.1\|WP_000025458.1\|783276_784146_+\|succinate--CoA-ligase-subunit-alpha	gnl\|CDD\|180194	PRK05678, PRK05678, succinyl-CoA synthetase subunit alpha; Validated.	0
NC_008253.1\|WP_000263355.1\|774378_774783_+\|succinate-dehydrogenase-cytochrome-b556-subunit	gnl\|CDD\|181900	PRK09487, sdhC, succinate dehydrogenase cytochrome b556 subunit.	3.50714e-82
NC_008253.1\|WP_000568275.1\|788414_789554_+\|cytochrome-d-ubiquinol-oxidase-subunit-II	gnl\|CDD\|184965	PRK15003, PRK15003, cytochrome d ubiquinol oxidase subunit II.	0
NC_008253.1\|WP_000254365.1\|774776_775124_+\|succinate-dehydrogenase-membrane-anchor-subunit	gnl\|CDD\|181901	PRK09488, sdhD, succinate dehydrogenase membrane anchor subunit.	5.54037e-58

>NC_008253.1|WP_001235263.1|776905_777622_+|succinate-dehydrogenase-iron-sulfur-subunit-SdhB
MRLEFSIYRYNPDVDDAPRMQDYTLEAEEGRDMMLLDALIQLKEKDPSLSFRRSCREGVCGSDGLNMNGKNGLACITPISALNQPGKKIVIRPLPGLPVIRDLVVDMGQFYAQYEKIKPYLLNNGQNPPAREHLQMPEQREKLDGLYECILCACCSTSCPSFWWNPDKFIGPAGLLAAYRFLIDSRDTETDSRLDGLSDAFSVFRCHSIMNCVSVCPKGLNPTRAIGHIKSMLLQRNA
>NC_008253.1|WP_000775540.1|775123_776890_+|succinate-dehydrogenase-flavoprotein-subunit
MKLPVREFDAVVIGAGGAGMRAALQISQSGQTCALLSKVFPTRSHTVSAQGGITVALGNTHEDNWEWHMYDTVKGSDYIGDQDAIEYMCKTGPEAILELEHMGLPFSRLDDGRIYQRPFGGQSKNFGGEQAARTAAAADRTGHALLHTLYQQNLKNHTTIFSEWYALDLVKNQDGAVVGCTALCIETGEVVYFKARATVLATGGAGRIYQSTTNAHINTGDGVGMAIRAGVPVQDMEMWQFHPTGIAGAGVLVTEGCRGEGGYLLNKHGERFMERYAPNAKDLAGRDVVARSIMIEIREGRGCDGPWGPHAKLKLDHLGKEVLESRLPGILELSRTFAHVDPVKEPIPVIPTCHYMMGGIPTKVTGQALTVNEKGEDVVVPGLFAVGEIACVSVHGANRLGGNSLLDLVVFGRAAGLHLQESIAEQGALRDASESDVEASLDRLNRWNNNRNGEDPVAIRKALQECMQHNFSVFREGDAMAKGLEQLKVIRERLKNARLDDTSSEFNTQRVECLELDNLMETAYATAVSANFRTESRGAHSRFDFPDRDDENWLCHSLYLPESESMTRRSVNMEPKLRPAFPPKIRTY
>NC_008253.1|WP_000254365.1|774776_775124_+|succinate-dehydrogenase-membrane-anchor-subunit
MVSNASALGRNGVHDFILVRATAIVLTLYIIYMVGFFATSGELTYEVWIGFFASAFTKVFTLLALFSILIHAWIGMWQVLTDYVKPLALRLMLQLVIVVALVVYVIYGFVVVWGV
>NC_008253.1|WP_000263355.1|774378_774783_+|succinate-dehydrogenase-cytochrome-b556-subunit
MWALFMIRNVKKQRPVNLDLQTIRFPVTAIASILHRVSGVITFVAVGILLWLLGTSLSSPEGFEQASAIMGSFFVKFIMWGILTALAYHVVVGIRHMMMDFGYLEETFEAGKRSAKISFVITVVLSLLAGVLVW
>NC_008253.1|WP_001305582.1|773890_773998_-|hypothetical-protein
MRKSYEVGISPKINLCNSVEVLTNSFGTVISGRQV
>NC_008253.1|WP_000785834.1|772401_773685_-|citrate-(Si)-synthase
MADTKAKLTLNGDTAVELDVLKGTLGQDVIDIRTLGSKGVFTFDPGFTSTASCESKITFIDGDEGILLHRGFPIDQLATDSNYLEVCYILLNGEKPTQEQYDEFKTTVTRHTMIHEQITRLFHAFRRDSHPMAVMCGITGALAAFYHDSLDVNNPRHREIAAFRLLSKMPTMAAMCYKYSIGQPFVYPRNDLSYAGNFLNMMFSTPCEPYEVNPILERAMDRILILHADHEQNASTSTVRTAGSSGANPFACIAAGIASLWGPAHGGANEAALKMLEEISSVKHIPEFVRRAKDKNDSFRLMGFGHRVYKNYDPRATVMRETCHEVLKELGTKDDLLEVAMELENIALNDPYFIEKKLYPNVDFYSGIILKAMGIPSSMFTVIFAMARTVGWIAHWSEMHSDGMKIARPRQLYTGYEKRDFKSDIKR
>NC_008253.1|WP_001144719.1|770681_771728_-|AbrB-family-transcriptional-regulator
MPVLQWGMLCVLSLLLSIGFLALHLPAALLLGPMIAGIIFSMRGVTLQLPRSAFLAAQAILGCMIAQNLTGSILTTLAVNWPIVLAILLVTLLSSAIVGWLLVRYSSLPGNTGAWGSSPGGAAAMVAMAQDYGADIRLVAFMQYLRVLFVAGAAVLVTRMMLGDNAEAVNQQIVWFPPVSINLLLTILLAVVAGTAGCLLRLPSGTMLIPMLAGAVLQSGQLITIELPEWLLAMAYMAIGWRIGLGFDKQILLRALRPLPQILLSIFALLAICAGMAWGLTRFMHIDFMTAYLATSPGGLDTVAVIAAGSNADMALIMAMQTLRLFSILLTGPAIARFISTYAPKRSA
>NC_008253.1|WP_001114006.1|769893_770685_+|endonuclease-VIII
MPEGPEIRRAADNLEAAIKGKPLTDVWFAFPQLKSYQSRLIGQHVTHVETRGKALLTHFSNDLTLYSHNQLYGVWRVVDTGEEPQTTRVLRVKLQTADKTILLYSASDIEMLTPEQLTTHPFLQRVGPDVLDPNLTPEVVKERLLSPRFRNRQFAGLLLDQAFLAGLGNYLRVEILWQVGLTGNHKAKDLNAAQLDALAHALLDIPRLSYATRGQVDENKYHGALFRFKVFHRDGEPCERCGGIIEKTTLSSRPFYWCPGCQH
>NC_008253.1|WP_000687123.1|769123_769858_+|5-oxoprolinase-subunit-PxpA
MKIDLNADLGEGCASDAELLTLVSSANIACGFHAGDAQTMQACVREAIKNGVAIGAHPSFPDRENFGRSAMQLPPETVFAQTLYQIGALAAITRAQGGVMCHVKPHGMLYNQAAKEAQLADAIARAVYACDPALILVGLAGSELIRAGERYGLVTREEVFADRGYQADGSLVPRSQPGALIENEEQALAQTLEMVQYGRVKSITGEWAMVTAQTVCLHGDGEHALAFARRLRATFAEKGIVVAA
>NC_008253.1|WP_000912741.1|768201_769134_+|5-oxoprolinase-subunit-PxpC
MLKIIRAGMYTTVQDGGRHGFRQSGISHCGALDMPALRIANLLVGNDANAPALEITLGQLTVEFETDGWFALTGAGCEARLDDNAVWTGWRLPMRAGQRLTLKRPQHGMRSYLAVAGGIDVPPVMGSCNTDLKVGIGGLEGRLLRDGDRLPIGKAKRDFMEAQGVKQLLWGNRIRALPGPEYHEFDRASQDAFWRSPWQLSSQSNRMGYRLQGQILKRTTDRELLSHGLLPGVVQVPHNGQPIVLMNDAQTTGGYPRIACIIEADMYHLAQIPLGQPIHFVQCSLEEALKARQDQQRYFEQLAWRLHNEN
>NC_008253.1|WP_001181473.1|777983_780785_+|2-oxoglutarate-dehydrogenase-E1-component
MQNSALKAWLDSSYLSGANQSWIEQLYEDFLTDPDSVDANWRSTFQQLPGTGVKPDQFHSQTREYFRRLAKDASRYSSTISDPDTNVKQVKVLQLINAYRFRGHQHANLDPLGLWQQDKVADLDPSFHDLTEADFQETFNVGSFASGKETMKLGELLEALKQTYCGPIGAEYMHITSTEEKRWIQQRIESGRATFNSEEKKRFLSELTAAEGLERYLGAKFPGAKRFSLEGGDALIPMLKEMIRHAGNSGTREVVLGMAHRGRLNVLVNVLGKKPQDLFDEFAGKHKEHLGTGDVKYHMGFSSDFQTDGGLVHLALAFNPSHLEIVSPVVIGSVRARLDRLDEPSSNKVLPITIHGDAAVTGQGVVQETLNMSKARGYEVGGTVRIVINNQVGFTTSNPLDARSTPYCTDIGKMVQAPIFHVNADDPEAVAFVTRLALDFRNTFKRDVFIDLVCYRRHGHNEADEPSATQPLMYQKIKKHPTPRKIYADKLEQEKVATLEDATEMVNLYRDALDAGDCVVAEWRPMNMHSFTWSPYLNHEWDEEYPNKVEMKRLQELAKRISTVPEAVEMQSRVAKIYGDRQAMAAGEKLFDWGGAENLAYATLVDEGIPVRLSGEDSGRGTFFHRHAVIHNQSNGSTYTPLQHIHNGQGAFRVWDSVLSEEAVLAFEYGYATAEPRTLTIWEAQFGDFANGAQVVIDQFISSGEQKWGRMCGLVMLLPHGYEGQGPEHSSARLERYLQLCAEQNMQVCVPSTPAQVYHMLRRQALRGMRRPLVVMSPKSLLRHPLAVSSLEELANGTFLPAIGEIDELDPKGVKRVVMCSGKVYYDLLEQRRKNNQHDVAIVRIEQLYPFPHKAMQEVLQQFAHVKDFVWCQEEPLNQGAWYCSQHHFREVIPFGASLRYAGRPASASPAVGYMSVHQKQQQDLVNDALNVE
>NC_008253.1|WP_000099829.1|780799_782017_+|2-oxoglutarate-dehydrogenase-complex-dihydrolipoyllysine-residue-succinyltransferase
MSSVDILVPDLPESVADATVATWHKKPGDAVVRDEVLVEIETDKVVLEVPASADGILDAVLEDEGTTVTSRQILGRLREGNSAGKETSAKSEEKASTPAQRQQASLEEQNNDALSPAIRRLLAEHNLDASAIKGTGVGGRLTREDVEKHLAKAPAKESAPAAAAPAAQPTLAARSEKRVPMTRLRKRVAERLLEAKNSTAMLTTFNEVNMKPIMDLRKQYGEAFEKRHGIRLGFMSFYVKAVVEALKRYPEVNASIDGDDVVYHNYFDVSMAVSTPRGLVTPVLRDVDTLGMADIEKKIKELAVKGRDGKLTVEDLTGGNFTITNGGVFGSLMSTPIINPPQSAILGMHAIKDRPMAVNGQVEILPMMYLALSYDHRLIDGRESVGFLVTIKELLEDPTRLLLDV
>NC_008253.1|WP_001048602.1|782110_783277_+|ADP-forming-succinate--CoA-ligase-subunit-beta
MNLHEYQAKQLFARYGLPAPVGYACTTPREAEEAASKIGAGPWVVKCQVHAGGRGKAGGVKVVNSKEDIRAFAENWLGKRLVTYQTDANGQPVNQILVEAATDIAKELYLGAVVDRSSRRVVFMASTEGGVEIEKVAEETPHLIHKVALDPLTGPMPYQGRELAFKLGLEGKLVQQFTKIFMGLATIFLERDLALIEINPLVITKQGDLICLDGKLGADGNALFRQPDLREMRDQSQEDPREAQAAQWELNYVALDGNIGCMVNGAGLAMGTMDIVKLHGGEPANFLDVGGGATKERVTEAFKIILSDDKVKAVLVNIFGGIVRCDLIADGIIGAVAEVGVNVPVVVRLEGNNAELGAKKLADSGLNIIAAKGLTDAAQQVVAAVEGK
>NC_008253.1|WP_000025458.1|783276_784146_+|succinate--CoA-ligase-subunit-alpha
MSILIDKNTKVICQGFTGSQGTFHSEQAIAYGTKMVGGVTPGKGGTTHLGLPVFNTVREAVAATGATASVIYVPAPFCKDSILEAIDAGIKLIITITEGIPTLDMLTVKVKLDEAGVRMIGPNCPGVITPGECKIGIQPGHIHKPGKVGIVSRSGTLTYEAVKQTTDYGFGQSTCVGIGGDPIPGSNFIDILEMFEKDPQTEAIVMIGEIGGSAEEEAAAYIKEHVTKPVVGYIAGVTAPKGKRMGHAGAIIAGGKGTADEKFAALEAAGVKTVRSLADIGEALKTVLK
>NC_008253.1|WP_000538734.1|784385_785501_+|tetratricopeptide-repeat-protein
MGVNSDVYAADVNIDILSATVKDKRIEGVSVTLQRNGAQSVSGTTNASGSVNLGSTFADDQDALLIVKKEGYSNLVVKCSCAGMTYAISPAMTSLDGMRVVLSWGEKPFDLDSHLIFPGGHIYFDSKEGTDANLDVDDTDSYGSKTVTISKKHFGESYIYAVQDYSNKGLPNSNYLSASKAKVFVYVGSSLVRSYSVPAGKRGNIWTVFKLNPNGEFEDINSVTSANFNDTTLDVRDLATVIMPATDSSAPASPAMQNSGDTQLARKYNREGEAVYKTGQLEQAIQLFQQATELDGNYGQAFSNLGLAYQKNGNIAEAIWANRKAISLASGANAATTRANSYYNIAKIYETAGQDADALQHYQLALHDAIL
>NC_008253.1|WP_000884361.1|786830_788399_+|cytochrome-ubiquinol-oxidase-subunit-I
MLDIVELSRLQFALTAMYHFLFVPLTLGMAFLLAIMETVYVLSGKQIYKDMTKFWGKLFGINFALGVATGLTMEFQFGTNWSYYSHYVGDIFGAPLAIEGLMAFFLESTFVGLFFFGWDRLGKVQHMCVTWLVALGSNLSALWILVANGWMQNPIASDFNFETMRMEMVSFSELVLNPVAQVKFVHTVASGYVTGAMFILGISAWYMLKGRDFAFAKRSFAIAASFGMAAVLSVIVLGDESGYEMGDVQKTKLAAIEAEWETQPAPAAFTLFGIPDQEEETNKFAIQIPYALGIIATRSVDTPVIGLKELMVQHEERIRNGMKAYSLLEQLRSGSTDQAVRDQFNSMKKDLGYGLLLKRYTPNVADATEAQIQQATKDSIPRVAPLYFAFRIMVACGFLLLAIIALSFWSVIRNRIGEKKWLLRAALYGIPLPWIAVEAGWFVAEYGRQPWAIGEVLPTAVANSSLTAGDLIFSMVLICGLYTLFLVAELFLMFKFARLGPSSLKTGRYHFEQSSTTTQPAR
>NC_008253.1|WP_000568275.1|788414_789554_+|cytochrome-d-ubiquinol-oxidase-subunit-II
MIDYEVLRFIWWLLVGVLLIGFAVTDGFDMGVGMLTRFLGRNDTERRIMINSIAPHWDGNQVWLITAGGALFAAWPMVYAAAFSGFYVAMILVLASLFFRPVGFDYRSKIEETRWRNMWDWGIFIGSFVPPLVIGVAFGNLLQGVPFNVDEYLRLYYTGNFFQLLNPFGLLAGVVSVGMIITQGATYLQMRTVGELHLRTRATAQVAALVTLVCFALAGVWVMYGIDGYVVKSTMDHYAASNPLNKEVVREAGAWLVNFNNTPILWAIPALGVVLPLLTILTARMDKAAWAFVFSSLTLACIILTAGIAMFPFVMPSSTMMNASLTMWDATSSQLTLNVMTWVAVVLVPIILLYTAWCYWKMFGRITKEDIERNTHSLY
>NC_008253.1|WP_000270282.1|789568_789682_+|cytochrome-bd-I-oxidase-subunit-CydX
MWYFAWILGTLLACSFGVITALALEHVESGKAGQEDI
>NC_008253.1|WP_000034602.1|789681_789975_+|cyd-operon-protein-YbgE
MSKIIATLYAVMDKRPLRALSFVMALLLAGCMFWDPSRFAAKTSELEIWHGLLLMWAVCAGVIHGVGFRPQKVLWQGIFCPLLADIVLIVGLIFFFF
>NC_008253.1|WP_001098375.1|790124_790529_+|tol-pal-system-associated-acyl-CoA-thioesterase
MNTTLFRWPVRVYYEDTDAGGVVYHASYVAFYERARTEMLRHHHFSQQALMAERIAFVVRKMTVEYYAPARLDDMLEIQTEITSMRGTSLVFTQRIVNAENTLLNEAEVLVVCVDPLKMKPRALPKSIVAEFKQ

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Crispr_ID: NC_008253_3

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_008253_3

939486-939633

Orphan

I-F

Consensus_repeat	Method
GTTCACTGCCGTACAGGCAGCTTAGAAA	CRISPRCasFinder

2 spacers

The CRISPR arrays of NC_008253_3

>merge|NC_008253|3|939486-939633|CRISPRCasFinder
GTTCACTGCCGTACAGGCAGCTTAGAAAGCACACGTCGAGCTGGTGGGGATTAATGCTGGGTTCACTGCCGTACAGGCAGCTTAGAAATTGCCGCGGATCCTGTCTGCCAATAATGACAAGTTCACTGCCGTACAGGCAGATAAAATG

>NC_008253|3|3|939486-939633|CRISPRCasFinder
GTTCACTGCCGTACAGGCAGCTTAGAAA	GCACACGTCGAGCTGGTGGGGATTAATGCTGG
GTTCACTGCCGTACAGGCAGCTTAGAAA	TTGCCGCGGATCCTGTCTGCCAATAATGACAA
GTTCACTGCCGTACAGGCAGATAAAATG

Protein	Signature genes	Signature genes Name	Protein_function
NC_008253.1\|WP_000599809.1\|930205_931864_+\|ATP-dependent-endonuclease	unknown	unknown	gnl\|CDD\|226121
NC_008253.1\|WP_000520781.1\|936645_936966_+\|ATP-dependent-Clp-protease-adapter-ClpS	unknown	unknown	gnl\|CDD\|178809
NC_008253.1\|WP_001351020.1\|931860_932817_-\|DUF535-domain-containing-protein	unknown	unknown	gnl\|CDD\|225537
NC_008253.1\|WP_000410785.1\|936098_936323_-\|cold-shock-like-protein-CspD	unknown	unknown	gnl\|CDD\|77494
NC_008253.1\|WP_000458842.1\|926068_927721_-\|hydroxylamine-reductase	unknown	unknown	gnl\|CDD\|235391
NC_008253.1\|WP_024174314.1\|951153_951765_+\|outer-membrane-lipoprotein-chaperone-LolA	unknown	unknown	gnl\|CDD\|129638
NC_008253.1\|WP_000491135.1\|927864_928764_-\|L-lysine-exporter-LysO	unknown	unknown	gnl\|CDD\|225287
NC_008253.1\|WP_000188148.1\|934079_936026_+\|macrolide-ABC-transporter-ATP-binding-protein/permease-MacB	unknown	unknown	gnl\|CDD\|182528
NC_008253.1\|WP_000934027.1\|936996_939273_+\|ATP-dependent-Clp-protease-ATP-binding-subunit-ClpA	unknown	unknown	gnl\|CDD\|236828
NC_008253.1\|WP_000886683.1\|953209_954502_+\|serine--tRNA-ligase	unknown	unknown	gnl\|CDD\|235461
NC_008253.1\|WP_001241673.1\|940519_941224_-\|leucyl/phenylalanyl-tRNA--protein-transferase	unknown	unknown	gnl\|CDD\|234720
NC_008253.1\|WP_000537432.1\|944876_945842_-\|thioredoxin-disulfide-reductase	unknown	unknown	gnl\|CDD\|182343
NC_008253.1\|WP_001202199.1\|941265_942987_-\|cysteine/glutathione-ABC-transporter-ATP-binding-protein/permease-CydC	unknown	unknown	gnl\|CDD\|236865
NC_008253.1\|WP_000077102.1\|947014_950995_+\|DNA-translocase-FtsK	unknown	unknown	gnl\|CDD\|236669
NC_008253.1\|WP_001298299.1\|929084_929780_-\|aquaporin-Z	unknown	unknown	gnl\|CDD\|235453
NC_008253.1\|WP_001043558.1\|942987_944754_-\|cysteine/glutathione-ABC-transporter-permease/ATP-binding-protein-CydD	unknown	unknown	gnl\|CDD\|236870
NC_008253.1\|WP_000067755.1\|951775_953119_+\|replication-associated-recombination-protein-RarA	unknown	unknown	gnl\|CDD\|237355
NC_008253.1\|WP_000746478.1\|932967_934083_+\|macrolide-transporter-subunit-MacA	unknown	unknown	gnl\|CDD\|183211
NC_008253.1\|WP_001040187.1\|940016_940235_-\|translation-initiation-factor-IF-1	unknown	unknown	gnl\|CDD\|178954
NC_008253.1\|WP_000228473.1\|946385_946880_+\|leucine-responsive-transcriptional-regulator-Lrp	unknown	unknown	gnl\|CDD\|183009

Protein	Function_ID	Function_description	E-value
NC_008253.1\|WP_000599809.1\|930205_931864_+\|ATP-dependent-endonuclease	gnl\|CDD\|226121	COG3593, COG3593, Predicted ATP-dependent endonuclease of the OLD family [DNA replication, recombination, and repair].	0
NC_008253.1\|WP_000520781.1\|936645_936966_+\|ATP-dependent-Clp-protease-adapter-ClpS	gnl\|CDD\|178809	PRK00033, clpS, ATP-dependent Clp protease adaptor protein ClpS; Reviewed.	2.48686e-49
NC_008253.1\|WP_001351020.1\|931860_932817_-\|DUF535-domain-containing-protein	gnl\|CDD\|225537	COG2990, VirK, Uncharacterized protein conserved in bacteria [Function unknown].	3.43529e-131
NC_008253.1\|WP_000410785.1\|936098_936323_-\|cold-shock-like-protein-CspD	gnl\|CDD\|77494	PRK09937, PRK09937, cold shock-like protein CspD.	1.48016e-47
NC_008253.1\|WP_000458842.1\|926068_927721_-\|hydroxylamine-reductase	gnl\|CDD\|235391	PRK05290, PRK05290, hybrid cluster protein; Provisional.	0
NC_008253.1\|WP_024174314.1\|951153_951765_+\|outer-membrane-lipoprotein-chaperone-LolA	gnl\|CDD\|129638	TIGR00547, Outer-membrane_lipoprotein_carrier_protein, periplasmic chaperone LolA. This protein, LolA, is known so far only in the gamma and beta subdivisions of the Proteobacteria. The E. coli major outer lipoprotein (Lpp) of E. coli is released from the inner membrane as a complex with this chaperone in an energy-requiring process, and is then delivered to LolB for insertion into the outer membrane. LolA is involved in the delivery of lipoproteins generally, rather than just Lpp, and is an essential protein in E. coli, unlike Lpp itself. [Protein fate, Protein and peptide secretion and trafficking].	2.45594e-124
NC_008253.1\|WP_000491135.1\|927864_928764_-\|L-lysine-exporter-LysO	gnl\|CDD\|225287	COG2431, COG2431, Predicted membrane protein [Function unknown].	1.20561e-117
NC_008253.1\|WP_000188148.1\|934079_936026_+\|macrolide-ABC-transporter-ATP-binding-protein/permease-MacB	gnl\|CDD\|182528	PRK10535, PRK10535, macrolide ABC transporter ATP-binding protein/permease MacB.	0
NC_008253.1\|WP_000934027.1\|936996_939273_+\|ATP-dependent-Clp-protease-ATP-binding-subunit-ClpA	gnl\|CDD\|236828	PRK11034, clpA, ATP-dependent Clp protease ATP-binding subunit; Provisional.	0
NC_008253.1\|WP_000886683.1\|953209_954502_+\|serine--tRNA-ligase	gnl\|CDD\|235461	PRK05431, PRK05431, seryl-tRNA synthetase; Provisional.	0
NC_008253.1\|WP_001241673.1\|940519_941224_-\|leucyl/phenylalanyl-tRNA--protein-transferase	gnl\|CDD\|234720	PRK00301, aat, leucyl/phenylalanyl-tRNA--protein transferase; Reviewed.	1.60016e-139
NC_008253.1\|WP_000537432.1\|944876_945842_-\|thioredoxin-disulfide-reductase	gnl\|CDD\|182343	PRK10262, PRK10262, thioredoxin reductase; Provisional.	0
NC_008253.1\|WP_001202199.1\|941265_942987_-\|cysteine/glutathione-ABC-transporter-ATP-binding-protein/permease-CydC	gnl\|CDD\|236865	PRK11160, PRK11160, cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed.	0
NC_008253.1\|WP_000077102.1\|947014_950995_+\|DNA-translocase-FtsK	gnl\|CDD\|236669	PRK10263, PRK10263, DNA translocase FtsK; Provisional.	0
NC_008253.1\|WP_001298299.1\|929084_929780_-\|aquaporin-Z	gnl\|CDD\|235453	PRK05420, PRK05420, aquaporin Z; Provisional.	2.04944e-144
NC_008253.1\|WP_001043558.1\|942987_944754_-\|cysteine/glutathione-ABC-transporter-permease/ATP-binding-protein-CydD	gnl\|CDD\|236870	PRK11174, PRK11174, cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed.	0
NC_008253.1\|WP_000067755.1\|951775_953119_+\|replication-associated-recombination-protein-RarA	gnl\|CDD\|237355	PRK13342, PRK13342, recombination factor protein RarA; Reviewed.	0
NC_008253.1\|WP_000746478.1\|932967_934083_+\|macrolide-transporter-subunit-MacA	gnl\|CDD\|183211	PRK11578, PRK11578, macrolide transporter subunit MacA; Provisional.	0
NC_008253.1\|WP_001040187.1\|940016_940235_-\|translation-initiation-factor-IF-1	gnl\|CDD\|178954	PRK00276, infA, translation initiation factor IF-1; Validated.	8.41354e-49
NC_008253.1\|WP_000228473.1\|946385_946880_+\|leucine-responsive-transcriptional-regulator-Lrp	gnl\|CDD\|183009	PRK11169, PRK11169, leucine-responsive transcriptional regulator Lrp.	5.32926e-117

>NC_008253.1|WP_000934027.1|936996_939273_+|ATP-dependent-Clp-protease-ATP-binding-subunit-ClpA
MLNQELELSLNMAFARAREHRHEFMTVEHLLLALLSNPSAREALEACSVDLVALRQELEAFIEQTTPVLPASEEERDTQPTLSFQRVLQRAVFHVQSSGRNEVTGANVLVAIFSEQESQAAYLLRKHEVSRLDVVNFISHGSRKDEPTQSSDPGSQPNSEEQAGGEERMENFTTNLNQLARVGGIDPLIGREKELERAIQVLCRRRKNNPLLVGESGVGKTAIAEGLAWRIVQGDVPEVMADCTIYSLDIGSLLAGTKYRGDFEKRFKALLKQLEQDTNSILFIDEIHTIIGAGAASGGQVDAANLIKPLLSSGKIRVIGSTTYQEFSNIFEKDRALARRFQKIDITEPSIEETVQIINGLKPKYEAHHDVRYTAKAVRAAVELAVKYINDRHLPDKAIDVIDEAGARARLMPVSKRKKTVNVADIESVVARIARIPEKSVSQSDRDTLKNLGDRLKMLVFGQDKAIEALTEAIKMARAGLGHEHKPVGSFLFAGPTGVGKTEVTVQLSKALGIELLRFDMSEYMERHTVSRLIGAPPGYVGFDQGGLLTDAVIKHPHAVLLLDEIEKAHPDVFNILLQVMDNGTLTDNNGRKADFRNVVLVMTTNAGVRETERKSIGLIHQDNSTDAMEEIKKIFTPEFRNRLDNIIWFDHLSTDVIHQVVDKFIVELQVQLDQKGVSLEVSQEARNWLAEKGYDRAMGARPMARVIQDNLKKPLANELLFGSLVDGGQVTVALDKEKNELTYGFQSAQKHKAEAAH
>NC_008253.1|WP_000520781.1|936645_936966_+|ATP-dependent-Clp-protease-adapter-ClpS
MGKTNDWLDFDQLAEEKVRDALKPPSMYKVILVNDDYTPMEFVIDVLQKFFSYDVERATQLMLAVHYQGKAICGVFTAEVAETKVAMVNKYARENEHPLLCTLEKA
>NC_008253.1|WP_000410785.1|936098_936323_-|cold-shock-like-protein-CspD
MEKGTVKWFNNAKGFGFICPEGGGEDIFAHYSTIQMDGYRTLKAGQSVQFDVHQGPKGNHASVIVPVEVEAAVA
>NC_008253.1|WP_000188148.1|934079_936026_+|macrolide-ABC-transporter-ATP-binding-protein/permease-MacB
MTPLLELKDIRRSYPAGDEQVEVLKGISLDIYAGEMVAIVGASGSGKSTLMNILGCLDKATSGTYRVAGQDVATLDADALAQLRREHFGFIFQRYHLLSHLTAEQNVEVPAVYAGLERKQRLLRAQELLQRLGLEDRTEYYPAQLSGGQQQRVSIARALMNGGQVILADEPTGALDSHSGEEVMAILHQLRDRGHTVIIVTHDPQVAAQAERVIEIRDGEIVRNPPAVEKVNATGGTEPVVNTASGWRQFVSGFNEALTMAWRALAANKMRTLLTMLGIIIGIASVVSIVVVGDAAKQMVLADIRSIGTNTIDVYPGNDFGDDDPQYQQALKYDDLIAIQKQPWVASATPAVSQNLRLRYNNVDVAASANGVSGDYFNVYGMTFSEGNTFNQEQLNGRAQVVVLDSNTRRQLFPHKADVVGEVILVGNMPARVIGVAEEKQSMFGSSKVLRVWLPYSTMSGRVMGQSWLNSITVRVKEGFDSAEAEQQLTRLLSLRHGKKDFFTWNMDGVLKTVEKTTRTLQLFLTLVAVISLVVGGIGVMNIMLVSVTERTREIGIRMAVGARASDVLQQFLIEAVLVCLVGGALGITLSLLIAFTLQLFLPGWEIGFSPLALLLAFLCSTVTGILFGWLPARNAARLDPVDALARE
>NC_008253.1|WP_000746478.1|932967_934083_+|macrolide-transporter-subunit-MacA
MKKRKTVKKRYVIAMVIVIAGLITLWRILNAPVPTYQTLIVRPGDLQQSVLATGKLDALRKVDVGAQVSGQLKTLSVAIGDKVKKDQLLGVIDPEQAENQIKEVEATLMELRAQRQQAEAELKLARVTYSRQQRLAQTQAVSQQDLDNAATEMAVKQAQIGTIDAQIKRNQASLDTAKTNLDYTRIVAPMAGEVTQITTLQGQTVIAAQQAPNILTLADMSTMLVKAQVSEADVIHLKPGQKAWFTVLGDPLTRYEGQIKDVLPTPEKINDAIFYYARFEVPNPNGLLRLDMTAQVHIQLTDVKNVLTIPLSALGDPVGDNRYKVKLLRNGETREREVTIGARNDTDVEIVKGLEAGDEVVIGEAKPGAAQ
>NC_008253.1|WP_001351020.1|931860_932817_-|DUF535-domain-containing-protein
MNMSQLTERTFTPSESLSSLSLFLSLARGQCRPGKFWHRRSFRQKFLLRSLIMPRLSVEWMNELSHWPNLNVLLTRQPRLPVRLHRPYLAANLSRKQLLEALRYHYALLRGCMSAEEFSLYLNTPGLQLAKLEGKNGEQFTLELTMMISMDKEGDSTILFRNSEGIPLAELTFTLCEYQGKRTMFIGGLQGAKWEIPHQEIQNATKACHGLFPKRLVMEAACLFAQRLQVEQIIAVSNETHIYRSLRYRDKEGKIHADYNAFWESVGGVCDAERHYRLPAQIARKEIAEIASKKRAEYRRRYEMLDAIQPQMATMFCS
>NC_008253.1|WP_000599809.1|930205_931864_+|ATP-dependent-endonuclease
MILERVEIVGFRGINRLSLMLEQNNVLIGENAWGKSSLLDALTLLLSPESDLYHFERDDFWFPPGDINGREHHLHIILTFRESLPGRHRVRRYRPLEACWTPCTDGYHRIFYRLEGESAEDGSVMTLRSFLDKDGHPIDVEDINDQARHLVRLMPVLRLRDARFMRRIRNGTVPNVPNVEVTARQLDFLARELSSHPQNLSDGQIRQGLSAMVQLLEHYFSEQGAGQARYRLMRRRASNEQRSWRYLDIINRMIDRPGGRSYRVILLGLFATLLQAKGTLRLDKDARPLLLIEDPETRLHPIMLSVAWHLLNLLPLQRIATTNSGELLSLTPVEHVCRLVRESSRVAAWRLGPSGLSTEDSRRISFHIRFNRPSSLFARCWLLVEGETETWVINELARQCGHHFDAEGIKVIEFAQSGLKPLVKFARRMGIEWHVLVDGDEAGKKYAATVRSLLNNDREAEREHLTALPALDMEHFMYRQGFSDVFHRVAQIPENVPMNLRKVISKAIHRSSKPDLAIEVAMEAGRRGVDSVPTLLKKMFSRVLWLARGRAD
>NC_008253.1|WP_001298299.1|929084_929780_-|aquaporin-Z
MFRKLAAECFGTFWLVFGGCGSAVLAAGFPELGIGFAGVALAFGLTVLTMAFAVGHISGGHFNPAVTIGLWAGGRFPAKEVVGYVIAQVVGGIVAAALLYLIASGKTGFDAAASGFASNGYGEHSPGGYSMLSALVVELVLSAGFLLVIHGATDKFAPAGFAPIAIGLALTLIHLISIPVTNTSVNPARSTAVAIFQGGWALEQLWFFWVVPIVGGIIGGLIYRTLLEKRD
>NC_008253.1|WP_000491135.1|927864_928764_-|L-lysine-exporter-LysO
MFSGLLIILVPLIVGYLIPLRQKAALRVINQLLSWMVYLILFFMGISLAFLDNLASNLLAILHYSAVSITVILLCNIAALMWLERGLPWRNHHHQEKLPSRIAMALESLKLCGVVVIGFAIGLSGLAFLQHATEASEYTLILLLFLVGIQLRNNGMTLKQIVLNRRGMIVAVVVVASSLIGGLINAFILDLPINTALAMASGFGWYSLSGILLTESFGPVIGSAAFFNDLARELIAIMLIPGLIRRSRSTALGLCGATSMDFTLPVLQRTGGLDMVPAAIVHGFILSLLVPILIAFFSA
>NC_008253.1|WP_000458842.1|926068_927721_-|hydroxylamine-reductase
MFCVQCEQTIRTPAGNGCSYAQGMCGKTAETSDLQDLLIATLQGLSAWAVKAREYGIINHDVDSFAPRAFFSTLTNVNFDSPRIVGYAREAIALREALKAQCLAVDANARVDNPMADLQLMSDDLGELQRQAAEFTPNKDKAAIGENILGLRLLCLYGLKGAAAYMEHAHVLGQYDNDIYAQYHKIMAWLGTWPADMNALLECSMEIGQMNFKVMSILDAGETGKYGHPTPTQVNVKATAGKCILISGHDLKDLYNLLEQTEGTGVNVYTHGEMLPAHGYPELRKFKHLVGNYGSGWQNQQVEFARFPGPIVMTSNCIIDPTVGAYDDRIWTRSIVGWPGVRHLDGEDFSAVIAQAQQMAGFPYSEIPHLITVGFGRQTLLGAADTLIDLVSREKLRHIFLLGGCDGARGERHYFTDFATSVPDDCLILTLACGKYRFNKLEFGDIEGLPRLVDAGQCNDAYSAIILAVTLAEKLGCGVNDLPLSLVLSWFEQKAIVILLTLLSLGVKNIVTGPTAPGFLTPDLLAVLNEKFGLRSITTVEEDMKQLLSA
>NC_008253.1|WP_001040187.1|940016_940235_-|translation-initiation-factor-IF-1
MAKEDNIEMQGTVLETLPNTMFRVELENGHVVTAHISGKMRKNYIRILTGDKVTVELTPYDLSKGRIVFRSR
>NC_008253.1|WP_001241673.1|940519_941224_-|leucyl/phenylalanyl-tRNA--protein-transferase
MRLVQLSRHSIAFPSPEGALREPNGLLALGGDLSPARLLMAYQRGIFPWFSPGDPILWWSPDPRAVLWPESLHISRSMKRFHKRSPYRVTMNYAFGQVIEGCASDREEGTWITRGVVEAYHRLHELGHAHSIEVWREDELVGGMYGVAQGTLFCGESMFSRMENASKTALLVFCDEFIRHGGKLIDCQVLNDHTASLGACEIPRRDYLNYLNQMRLGRLPNNFWVPRCLFSPQE
>NC_008253.1|WP_001202199.1|941265_942987_-|cysteine/glutathione-ABC-transporter-ATP-binding-protein/permease-CydC
MRALLPYLALYKRHKWMLSLGIVLAIVTLLASIGLLTLSGWFLSASAVAGVAGLYSFNYMLPAAGVRGAAITRTAGRYFERLVSHDATFRVLQHLRIYTFSKLLPLSPAGLARYRQGELLNRVVADVDTLDHLYLRVISPLVGAFVVIMVVTIGLSFLDFTLAFTLGGIMLLTLFLMPPLFYRAGKSTGQNLTHLRGQYRQQLTAWLQGQAELTIFGASDRYRTQLENTEIQWLEAQRRQSELTALSQAIMLLIGALAVILMLWMASGGVGGNAQPGALIALFVFCALAAFEALAPVTGAFQHLGQVIASAVRITDLTDQKPEVTFPDTQTRVADRVSLTLRDVQFTYPEQSQQALKGIYLQVNAGEHIAILGRTGCGKSTLLQLLTRAWDPQQGEILLNDSPIASLNEAALRQTISVVPQRVHLFSATLRDNLLLASPGSSDEALAEILRRVGLEKLLEDAGLNSWLGEGGRQLSGGELRRLAIARALLHDAPLVLLDEPTEGLDATTESQILELLAEMMCEKTVLMVTHRLRGLSRFQQIIVMDNGQIIEQGTHAELLTRQGRYYQFKQGL
>NC_008253.1|WP_001043558.1|942987_944754_-|cysteine/glutathione-ABC-transporter-permease/ATP-binding-protein-CydD
MNKSRQKELTRWLKQQSVISQRWLNISRLLGFVSGILIIAQAWFMARILQHMIMENIPREALLLPFTLLFLTFVLRAWVVWLRERVGYHAGQHIRFAIRRQVLDRLQQAGPAWIQGKPAGSWATLVLEQIDDMHDYYARYLPQMALAVSVPLLIVVAIFPSNWAAALILLGTAPLIPLFMALVGMGAADANRRNFLALARLSGHFLDRLRGMETLRIFGRGEAEIESIRSASEDFRQRTMEVLRLAFLSSGILEFFTSLSIALVAIYFGFSYLGELDFGHYDTGVTLAAGFLALILAPEFFQPLRDLGTFYHAKAQAVGAADSLKTFMETPLAHPQRGEAELASTDPVTIEAEDLFITSPEGKTLAGPLNFTLPAGQRAVLVGRSGSGKSSLLNALSGFLSYQGSLRINGIELRDLSPESWRKHLSWVGQNPQLPAATLRDNVLLARPDASEQELQTALDNAWVSEFLPLLPQGIDTPVGDQAARLSVGQAQRVAVARALLNPCSLLLLDEPAASLDAHSEQRVMEALNAASLRQTTLMVTHQLEDLADWDVIWVMQDGQIIEQGRYAELSVAGGPFATLLAHRQEEI
>NC_008253.1|WP_000537432.1|944876_945842_-|thioredoxin-disulfide-reductase
MGTTKHSKLLILGSGPAGYTAAVYAARANLQPVLITGMEKGGQLTTTTEVENWPGDPNDLTGPLLMERMHEHATKFETEIIFDHINKVDLQNRPFRLTGDSGEYTCDALIIATGASARYLGLPSEEAFKGRGVSACATCDGFFYRNQKVAVIGGGNTAVEEALYLSNIASEVHLIHRRDGFRAEKILIKRLMDKVENGNIILHTNRTLEEVTGDQMGVTGVRLRDTQNSDNIESLDVAGLFVAIGHSPNTAIFEGQLELENGYIKVQSGIHGNATQTSIPGVFAAGDVMDHIYRQAITSAGTGCMAALDAERYLDGLADAK
>NC_008253.1|WP_000228473.1|946385_946880_+|leucine-responsive-transcriptional-regulator-Lrp
MVDSKKRPGKDLDRIDRNILNELQKDGRISNVELSKRVGLSPTPCLERVRRLERQGFIQGYTALLNPHYLDASLLVFVEITLNRGAPDVFEQFNTAVQKLEEIQECHLVSGDFDYLLKTRVPDMSAYRKLLGETLLRLPGVNDTRTYVVMEEVKQSNRLVIKTR
>NC_008253.1|WP_000077102.1|947014_950995_+|DNA-translocase-FtsK
MSQEYTEDKEVTLTKLSSGRRLLEALLILIVLFAVWLMAALLSFNPSDPSWSQTAWHEPIHNLGGMPGAWLADTLFFIFGVMAYTIPVIIVGGCWFAWRHQSSDEYIDYFAVSLRIIGVLALILTSCGLAAINADDIWYFASGGVIGSLLSTTLQPLLHSSGGTIALLCVWAAGLTLFTGWSWVTIAEKLGGWILNILTFASNRTRRDDTWVDEDEYEDDEEYEDENHGKQHESRRARILRGALARRKRLAEKFINPMGRQTDAALFSGKRMDDEEEITYTARGVAADPDDVLFSGNRATQPEYDEYDPLLNGAPITEPVAVAAAATTATQSWAAPVEPVTQTPPVASVDVPPTQPTVAWQPVPGPQTGEPVIAPAPEGYPHQSQYAQPAVQYNEPLQQPVQPQQPYYAPAAEQPVQQPYYAPAAEQPVQQPYYAPAPEQPVAGNAWQAEEQQSTFAPQSTYQTEQTYQQPAAQEPLYQQPQPVEQQPVVEPEPVVEETKPTRPPLYYFEEVEEKRAREREQLAAWYQPIPEPVKEPEPIKSSLKAPSVAAVPPVEAAAAVSPLASGVKKATLATGAAATVAAPVFSLANSGGPRPQVKEGIGPQLPRPKRIRVPTRRELASYGIKLPSQRAAEEKAREAQRNQYDSGDQYNDDEIDAMQQDELARQFAQTQQQRYGEQYQHDVPVNTEDADAAAEAELARQFAQTQQQRYSGEQPAGANPFSLDDFEFSPMKALLDDGPHEPLFTPIVEPVQQPQQPVAPQQQYQQPQYQQPQYQQPQQPVAQQPQYQQPQQPVAPQQQYQQPQQPVAPQPHDTLLHPLLMRNGDSRPLHKPTTPLPSLDLLTPPPSEVEPVDTFALEQMARLVEARLADFRIKADVVNYSPGPVITRFELNLAPGVKAARISNLSRDLARSLSTVAVRVVEVIPGKPYVGLELPNKKRQTVYLREVLDNAKFRDNPSPLTVVLGKDIAGEPVVADLAKMPHLLVAGTTGSGKSVGVNAMILSMLYKAQPEDVRFIMIDPKMLELSVYEGIPHLLTEVVTDMKDAANALRWCVNEMERRYKLMSALGVRNLAGYNEKIAEADRMMRPIPDPYWKPGDSMDAQHPVLKKEPYIVVLVDEFADLMMTVGKKVEELIARLAQKARAAGIHLVLATQRPSVDVITGLIKANIPTRIAFTVSSKIDSRTILDQAGAESLLGMGDMLYSGPNSTLPVRVHGAFVRDQEVHAVVQDWKARGRPQYVDGITSDSESEGGVGGFDGAEELDPLFDQAVQFVTEKRKASISGVQRQFRIGYNRAARIIEQMEAQGIVSEQGHNGNREVLAPPPFD
>NC_008253.1|WP_024174314.1|951153_951765_+|outer-membrane-lipoprotein-chaperone-LolA
MKKIAITCALLSSLVASSVWADAASDLKSRLDKVSSFHASFTQKVTDGSGAAVQEGQGDLWVKRPNLFNWHMTQPDESILVSDGKTLWFYNPFVEQATATWLKDATGNTPFMLIARNQSSDWQQYNIKQNGDDFVLTPKASNGNLKQFTINVGRDGTIHQFSAVEQDDQRSSYQLKSQQNGAVDAAKFTFTPAQGVTVDDQRK
>NC_008253.1|WP_000067755.1|951775_953119_+|replication-associated-recombination-protein-RarA
MSNLSLDFSDNTFQPLAARMRPENLAQYIGQQHLLAAGKPLPRAIEAGHLHSMILWGPPGTGKTTLAEVIARYANADVERISAVTSGVKEIREAIERARQNRNAGRRTILFVDEVHRFNKSQQDAFLPHIEDGTITFIGATTENPSFELNSALLSRARVYLLKSLSTEDIEQVLTQAMEDKTRGYGGQDIVLPDETRRAIAELVNGDARRALNTLEMMADMAEVDDSGKRVLKPELLTEIAGERSARFDNKGDRFYDLISALHKSVRGSAPDAALYWYARIITAGGDPLYVARRCLAIASEDVGNADPRAMQVAIAAWDCFTRVGPAEGERAIAQAIVYLACAPKSNAVYTAFKAALADARERPDYDVPVHLRNAPTKLMKEMGYGQEYRYAHDEANAYAAGEVYFPPEIAQTRYYFPTNRGLEGKIGEKLAWLAEQDQNSPIKRYR
>NC_008253.1|WP_000886683.1|953209_954502_+|serine--tRNA-ligase
MLDPNLLRNEPDAVAEKLARRGFKLDVDKLGALEERRKVLQVKTENLQAERNSRSKSIGQAKARGEDIEPLRLEVNKLGEELDAAKAELDALQAEIRDIALTIPNLPADEVPVGKDENDNVEVSRWGTPREFDFEVRDHVTLGEMHSGLDFAAAVKLTGSRFVVMKGQIARMHRALSQFMLDLHTEQHGYSENYVPYLVNQDTLYGTGQLPKFAGDLFHTRPLEEEADTSNYALIPTAEVPLTNLVRGEIIDEDDLPIKMTAHTPCFRSEAGSYGRDTRGLIRMHQFDKVEMVQIVRPEDSMAALEEMTGHAEKVLQLLGLPYRKIILCTGDMGFGACKTYDLEVWIPAQNTYREISSCSNVWDFQARRMQARCRSKSDKKTRLVHTLNGSGLAVGRTLVAVMENYQQADGRIEVPEVLRPYMNGLEYIG

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Crispr_ID: NC_008253_4

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_008253_4

2384255-2384368

Orphan

Consensus_repeat	Method
TTTGTAGGCCGGATAAGCGAAGCGCATCCGGCA	CRISPRCasFinder

1 spacers

The CRISPR arrays of NC_008253_4

>merge|NC_008253|4|2384255-2384368|CRISPRCasFinder
TTTGTAGGCCGGATAAGCGAAGCGCATCCGGCACTGGATGCCCAGATGCGGCATGAACGCCCTACCCAGCCTACGATGCGGTTTGTAGGCCGGATAAGCGAAGCGCATCCGGCA

>NC_008253|4|4|2384255-2384368|CRISPRCasFinder
TTTGTAGGCCGGATAAGCGAAGCGCATCCGGCA	CTGGATGCCCAGATGCGGCATGAACGCCCTACCCAGCCTACGATGCGG
TTTGTAGGCCGGATAAGCGAAGCGCATCCGGCA

Protein	Signature genes	Signature genes Name	Protein_function
NC_008253.1\|WP_000332036.1\|2384392_2385523_+\|ribonucleotide-diphosphate-reductase-subunit-beta	unknown	unknown	gnl\|CDD\|181647
NC_008253.1\|WP_000135041.1\|2385522_2385777_+\|ferredoxin-like-diferric-tyrosyl-radical-cofactor-maintenance-protein-YfaE	unknown	unknown	gnl\|CDD\|182668
NC_008253.1\|WP_000536494.1\|2366846_2371361_-\|alpha-2-macroglobulin-family-protein	unknown	unknown	gnl\|CDD\|225248
NC_008253.1\|WP_000948732.1\|2387764_2389123_-\|glycerol-3-phosphate-transporter	unknown	unknown	gnl\|CDD\|236889
NC_008253.1\|WP_001281242.1\|2373841_2376469_-\|DNA-topoisomerase-(ATP-hydrolyzing)-subunit-A	unknown	unknown	gnl\|CDD\|235502
NC_008253.1\|WP_001075170.1\|2381917_2384203_+\|ribonucleoside-diphosphate-reductase-subunit-alpha	unknown	unknown	gnl\|CDD\|181649
NC_008253.1\|WP_000857237.1\|2389395_2391024_+\|anaerobic-glycerol-3-phosphate-dehydrogenase-subunit-A	unknown	unknown	gnl\|CDD\|236847
NC_008253.1\|WP_024174325.1\|2377477_2381236_-\|AIDA-I-family-autotransporter-adhesin-YfaL/EhaC	unknown	unknown	gnl\|CDD\|182059
NC_008253.1\|WP_001104799.1\|2365196_2366846_-\|YfaQ-family-protein	unknown	unknown	gnl\|CDD\|227732
NC_008253.1\|WP_000786514.1\|2363157_2364342_+\|acetyl-CoA-acetyltransferase	unknown	unknown	gnl\|CDD\|180261
NC_008253.1\|WP_000992978.1\|2394850_2395654_-\|2-keto-3-deoxy-L-rhamnonate-aldolase	unknown	unknown	gnl\|CDD\|182257
NC_008253.1\|WP_000779093.1\|2386683_2387760_-\|glycerophosphodiester-phosphodiesterase	unknown	unknown	gnl\|CDD\|236859
NC_008253.1\|WP_000140537.1\|2393652_2394612_+\|ISNCY-family-transposase	unknown	unknown	gnl\|CDD\|182167
NC_008253.1\|WP_001000377.1\|2392269_2393460_+\|anaerobic-glycerol-3-phosphate-dehydrogenase-subunit-C	unknown	unknown	gnl\|CDD\|132422
NC_008253.1\|WP_000012348.1\|2372004_2373693_-\|DUF2138-domain-containing-protein	unknown	unknown	gnl\|CDD\|227030
NC_008253.1\|WP_001225875.1\|2364415_2365192_-\|YfaP-family-protein	unknown	unknown	gnl\|CDD\|227021
NC_008253.1\|WP_000301031.1\|2385830_2386481_-\|lipopolysaccharide-kinase-InaA	unknown	unknown	gnl\|CDD\|182136
NC_008253.1\|WP_000990783.1\|2376615_2377338_+\|bifunctional-3-demethylubiquinone-3-O-methyltransferase/2-octaprenyl-6-hydroxy-phenol-methylase	unknown	unknown	gnl\|CDD\|235350
NC_008253.1\|WP_001297934.1\|2371384_2372008_-\|DUF1175-domain-containing-protein	unknown	unknown	gnl\|CDD\|225774
NC_008253.1\|WP_000150339.1\|2394624_2394810_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|182167

Protein	Function_ID	Function_description	E-value
NC_008253.1\|WP_000332036.1\|2384392_2385523_+\|ribonucleotide-diphosphate-reductase-subunit-beta	gnl\|CDD\|181647	PRK09101, nrdB, ribonucleotide-diphosphate reductase subunit beta; Reviewed.	0
NC_008253.1\|WP_000135041.1\|2385522_2385777_+\|ferredoxin-like-diferric-tyrosyl-radical-cofactor-maintenance-protein-YfaE	gnl\|CDD\|182668	PRK10713, PRK10713, 2Fe-2S ferredoxin-like protein.	8.92472e-53
NC_008253.1\|WP_000536494.1\|2366846_2371361_-\|alpha-2-macroglobulin-family-protein	gnl\|CDD\|225248	COG2373, COG2373, Large extracellular alpha-helical protein [General function prediction only].	0
NC_008253.1\|WP_000948732.1\|2387764_2389123_-\|glycerol-3-phosphate-transporter	gnl\|CDD\|236889	PRK11273, glpT, glycerol-3-phosphate transporter.	0
NC_008253.1\|WP_001281242.1\|2373841_2376469_-\|DNA-topoisomerase-(ATP-hydrolyzing)-subunit-A	gnl\|CDD\|235502	PRK05560, PRK05560, DNA gyrase subunit A; Validated.	0
NC_008253.1\|WP_001075170.1\|2381917_2384203_+\|ribonucleoside-diphosphate-reductase-subunit-alpha	gnl\|CDD\|181649	PRK09103, PRK09103, ribonucleoside-diphosphate reductase subunit alpha.	0
NC_008253.1\|WP_000857237.1\|2389395_2391024_+\|anaerobic-glycerol-3-phosphate-dehydrogenase-subunit-A	gnl\|CDD\|236847	PRK11101, glpA, anaerobic glycerol-3-phosphate dehydrogenase subunit A.	0
NC_008253.1\|WP_024174325.1\|2377477_2381236_-\|AIDA-I-family-autotransporter-adhesin-YfaL/EhaC	gnl\|CDD\|182059	PRK09752, PRK09752, AIDA-I family autotransporter YfaL.	0
NC_008253.1\|WP_001104799.1\|2365196_2366846_-\|YfaQ-family-protein	gnl\|CDD\|227732	COG5445, COG5445, Predicted secreted protein [Function unknown].	8.69726e-124
NC_008253.1\|WP_000786514.1\|2363157_2364342_+\|acetyl-CoA-acetyltransferase	gnl\|CDD\|180261	PRK05790, PRK05790, putative acyltransferase; Provisional.	0
NC_008253.1\|WP_000992978.1\|2394850_2395654_-\|2-keto-3-deoxy-L-rhamnonate-aldolase	gnl\|CDD\|182257	PRK10128, PRK10128, 2-keto-3-deoxy-L-rhamnonate aldolase; Provisional.	0
NC_008253.1\|WP_000779093.1\|2386683_2387760_-\|glycerophosphodiester-phosphodiesterase	gnl\|CDD\|236859	PRK11143, glpQ, glycerophosphodiester phosphodiesterase; Provisional.	0
NC_008253.1\|WP_000140537.1\|2393652_2394612_+\|ISNCY-family-transposase	gnl\|CDD\|182167	PRK09956, PRK09956, ISNCY family transposase.	0
NC_008253.1\|WP_001000377.1\|2392269_2393460_+\|anaerobic-glycerol-3-phosphate-dehydrogenase-subunit-C	gnl\|CDD\|132422	TIGR03379, glycerol3P_GlpC, glycerol-3-phosphate dehydrogenase, anaerobic, C subunit. Members of this protein family are the membrane-anchoring, non-catalytic C subunit, product of the glpC gene, of a three-subunit, FAD-dependent, anaerobic glycerol-3-phosphate dehydrogenase. GlpC lasks classical hydrophobic transmembrane helices; Cole, et al suggest interaction with the membrane may involve amphipathic helices. GlcC has conserved Cys-containing motifs suggestive of iron-sulfur binding. This complex is found mostly in Escherichia coli and closely related species. [Energy metabolism, Anaerobic].	0
NC_008253.1\|WP_000012348.1\|2372004_2373693_-\|DUF2138-domain-containing-protein	gnl\|CDD\|227030	COG4685, COG4685, Uncharacterized protein conserved in bacteria [Function unknown].	0
NC_008253.1\|WP_001225875.1\|2364415_2365192_-\|YfaP-family-protein	gnl\|CDD\|227021	COG4676, COG4676, Uncharacterized protein conserved in bacteria [Function unknown].	4.7479e-153
NC_008253.1\|WP_000301031.1\|2385830_2386481_-\|lipopolysaccharide-kinase-InaA	gnl\|CDD\|182136	PRK09902, PRK09902, lipopolysaccharide kinase InaA.	3.42273e-158
NC_008253.1\|WP_000990783.1\|2376615_2377338_+\|bifunctional-3-demethylubiquinone-3-O-methyltransferase/2-octaprenyl-6-hydroxy-phenol-methylase	gnl\|CDD\|235350	PRK05134, PRK05134, bifunctional 2-polyprenyl-6-hydroxyphenol methylase/3-demethylubiquinol 3-O-methyltransferase UbiG.	1.45677e-171
NC_008253.1\|WP_001297934.1\|2371384_2372008_-\|DUF1175-domain-containing-protein	gnl\|CDD\|225774	COG3234, COG3234, Uncharacterized protein conserved in bacteria [Function unknown].	4.78627e-139
NC_008253.1\|WP_000150339.1\|2394624_2394810_+\|hypothetical-protein	gnl\|CDD\|182167	PRK09956, PRK09956, ISNCY family transposase.	7.27111e-31

>NC_008253.1|WP_001075170.1|2381917_2384203_+|ribonucleoside-diphosphate-reductase-subunit-alpha
MNQNLLVTKRDGSTERINLDKIHRVLDWAAEGLHNVSISQVELRSHIQFYDGIKTSDIHETIIKAAADLISRDAPDYQYLAARLAIFHLRKKAYGQFEPPALYDHVVKMVEMGKYDNHLLEDYTEEEFKQMDTFIDHDRDMTFSYAAVKQLEGKYLVQNRVTGEIYESAQFLYILVAACLFSNYPRETRLQYVKRFYDAVSTFKISLPTPIMSGVRTPTRQFSSCVLIECGDSLDSINATSSAIVKYVSQRAGIGINAGRIRALGSPIRGGEAFHTGCIPFYKHFQTAVKSCSQGGVRGGAATLFYPMWHLEVESLLVLKNNRGVEGNRVRHMDYGVQINKLMYTRLLKGEDITLFSPSDVPGLYDAFFADQEEFERLYTKYEKDDSIRKQRVKAVELFSLMMQERASTGRIYIQNVDHCNTHSPFDPAIAPVRQSNLCLEIALPTKPLNDVNDENGEIALCTLSAFNLGAINSLDELEELAILAVRALDALLDYQDYPIPAAKRGAMGRRTLGIGVINFAYYLAKHGKRYSDGSANNLTHKTFEAIQYYLLKASNELAKEQGACPWFNETTYAKGILPIDTYKKDLDAIANEPLHYDWEALRESIKTHGLRNSTLSALMPSETSSQISNATNGIEPPRGYVSIKASKDGILRQVVPDYEHLHDAYELLWEMPGNDGYLQLVGIMQKFIDQSISANTNYDPSRFPSGKVPMQQLLKDLLTAYKFGVKTLYYQNTRDGAEDAQDDLVPSIQDDGCESGACKI
>NC_008253.1|WP_024174325.1|2377477_2381236_-|AIDA-I-family-autotransporter-adhesin-YfaL/EhaC
MRIIFLRKEYLSLLPSMIASLFSGNGAAAVIDSCQGYDIKASCQASRQSLSGNMQDWSIADGQWLIFSGMANNASGGAVFLQHSAEFTISPQNETGMTLFADNSVSGEYNNGGAIFAKENSTINLANVIFDSNVAGGYGGAIYSAGTNDTGAADLRVTNAVFHNNIANDGKGGAIYTINNDVYLSDDAFNNNQAYTSTSYSDGDGGAIDVTDNSTDNTHLSGKTIINNTSFTNNYAEGYGGAIYTSSTTSPYLIDISVDDNYDQNNGVMIDENNSASGYDHSATAAAGGFMYIGHSVAEFNIAADKTLVIGNTSNDGAIDSLAGTGVIVKEGAGELVLNADNNAFTGEMSIQNGEVTLGRSDELMNVGDTHCQSDPQDCFGLMVGSTVHSEYQAELNVGNTQQTFVHSLTGFANGILNIDAGGNVTVNQGGFSGSIQGEGQLTVAQDGSYLLTGAQSMALTGDIVVEDNAVLSLAGNQADLRAMQSDPQSIVLNGGVLDLSDFTTWDGDSSYNDGLQISGSGGTVIGSNDVVDISSGDDLHIGGSDASQNGVYVVINAGDQRVTLANNNGYLGNTQIASGTLEVSDNSQLGDTSYNRSVIFTDPQQHSEMDVTTDVDTRSATTGQGRNIEMRADGEIHVEDGVDTQWGGLMADSTGQQLDSVSTLTKSGGGTLELTASGTATSAVRVEDGTLKGEAENIIPYVSSLWVGEDGVFETGQNQDIRSIDATSGGDIDITDGTVLRLTQQDTNQALDASLFSGDGTLVNATDGVTLAGELNTNLETDSLTYLSDVTVNGNLTNTSGAISLQNSVAGDTLTVNGDYTGGGTLFLDSELNGDDSASDQLVLNGNTSGNTTVVVNPITGIGEPTSTGIKVVDFAADPAQFQNNAQFSLAGSGYVNMGAYDYTLVEDNNDWYLRSQEVNPTPPPDPDPTPDPDPTPDPDPTPDPEPTPAYQPVLNAKVGGYFNNLRAANQAFVMERRDHAGGDGQTLNLRVIGGRYHYTAVGQLAQHEDTSTVQLSGNLFSGHWGDDGEWMLGIVGGYSDNQCDSRSNMTGTRADNQNHGYAVGLTSSWYQHGNQKQGAWLDSWLQYVWFNNDVSEQDDGVDHYHSSGIIASLEAGYQWLPGHGVVIEPQTQVIYQGVHQDDFTAANHARVSQSQGDDIQTRLGLHSEWRTAVGVTPTLDLNYYHDPHATEIEEDGSTISDDAVKQRGEIKVGITGNISQRVSLRGSVAWQKGSDDFAQTAGFLSMTVKW
>NC_008253.1|WP_000990783.1|2376615_2377338_+|bifunctional-3-demethylubiquinone-3-O-methyltransferase/2-octaprenyl-6-hydroxy-phenol-methylase
MNAEKSPVNHNVDHKEIAKFEAVASRWWDLEGEFKPLHRINPLRLGYIAERAGGLFGKKVLDVGCGGGILAESMAREGATVTGLDMGFEPLQVAKLHALESGIQVDYVQETVEEHAAKHAGQYDVVTCMEMLEHVPDPQSVVRACAQLVKPGGDVFFSTLNRNGKSWLMAVVGAEYILRMVPKGTHDVKKFIKPAELLGWVDQTSLKERHMTGLHYNPITNTFKLGPGVDVNYMLHTQNK
>NC_008253.1|WP_001281242.1|2373841_2376469_-|DNA-topoisomerase-(ATP-hydrolyzing)-subunit-A
MSDLAREITPVNIEEELKSSYLDYAMSVIVGRALPDVRDGLKPVHRRVLYAMNVLGNDWNKAYKKSARVVGDVIGKYHPHGDSAVYDTIVRMAQPFSLRYMLVDGQGNFGSIDGDSAAAMRYTEIRLAKIAHELMADLEKETVDFVDNYDGTEKIPDVMPTKIPNLLVNGSSGIAVGMATNIPPHNLTEVINGCLAYIDDEDISIEGLMEHIPGPDFPTAAIINGRRGIEEAYRTGRGKVYIRARAEVEVDAKTGRETIIVHEIPYQVNKARLIEKIAELVKEKRVEGISALRDESDKDGMRIVIEVKRDAVGEVVLNNLYSQTQLQVSFGINMVALHHGQPKIMNLKDIIAAFVRHRREVVTRRTIFELRKARDRAHILEALAVALANIDPIIELIRHAPTPAEAKTALVANPWQLGNVAAMLERAGDDAARPEWLEPEFGVRDGLYYLTEQQAQAILDLRLQKLTGLEHEKLLDEYKELLDQIAELLRILGSADRLMEVIREELELVREQFGDKRRTEITANSADINLEDLITQEDVVVTLSHQGYVKYQPLSEYEAQRRGGKGKSAARIKEEDFIDRLLVANTHDHILCFSSRGRVYSMKVYQLPEATRGARGRPIVNLLPLEQDERITAILPVTEFEEGVKVFMATANGTVKKTVLTEFNRLRTAGKVAIKLVDGDELIGVDLTSGEDEVMLFSAEGKVVRFKESSVRAMGCNTTGVRGIRLGEGDKVVSLIVPRGDGAILTATQNGYGKRTAVAEYPTKSRATKGVISIKVTERNGLVVGAVQVDDCDQIMMITDAGTLVRTRVSEISIVGRNTQGVILIRTAEDENVVGLQRVAEPVDEEDLDTIDGSAAEGDDEIAPEVDVDDEPEEE
>NC_008253.1|WP_000012348.1|2372004_2373693_-|DUF2138-domain-containing-protein
MSGEKKAKGWRFYGLVGLGAIVLLSTGVWALQYAGSGPEKTLSPLVVHNNLQIDLNEPDLFLDSDSLSQLPKDLLTIPFLHDVLSEDFVFYYQNHADRLGIEGSIRRIVYEHDLTLKDKLFSSLLDQPAQAALWHDKQGHLSHYMVLIQRSGLSKLLEPLLFAATSDSQLSKTEISSIKLNSETIPVYQLRYNGNNALMFATYQDKMLVFSSTDMLFKDDQQDTEAAAIASDLLSGKKRWETSFGLEERTAEKTPVRQRIVVSARLLGFGYQRLVPSFAGMRFEMGNDGWHSFLALNDESASVDASFDFTPVWNSMPAGASFCVAVPYSHGIAEEMLSHISQENDKLNGALDGGAGLCWYEDSKLQTPLFVGQFDGTAEQAQLPGKLFTQNIGAHESKAPEGVLPVSQTQQGEAQIWRREVSSRYGQYPKAQAAQPDQLMSDYFFRVSLAMQNKTLLFSLDDTLVNNALQALNKTRPAMVDVIPTDGIVPLYINPQGMAKLLRNETLTSLPKNLEPVFYNAAQTLLMPKLDALSQQPRYVMKLAQMEPGAAWQWLPITWQPL
>NC_008253.1|WP_001297934.1|2371384_2372008_-|DUF1175-domain-containing-protein
MRHGLLVLICWLYCVVAHSEMLNVEQSGLFRAWFVRIAQEQLRQGPSPRWYQQDCAGLVRFAANEALKVHDSKWLKSNGLSNQYLPPEMTLTPEQRQLAQNWNQGNGKTGPYVTAINLIQYNSQFIGQDINQALPGDMIFFDQGDAQHLMVWMGRYIIYHTGSATKTDNGMRAVSLQQLMTWKDTRWIPNDSNPNFIGIYRLNFLAR
>NC_008253.1|WP_000536494.1|2366846_2371361_-|alpha-2-macroglobulin-family-protein
MGTGLANADDSLPSSNYAPPAGGTFFLLADSSFSRSEEAKVRLEAPGRDYRRYQMEEYGGVDVRLYRIPDPMAFLRQQKNLHRIVVQPQYLGDGLNNTLTWLWDNWYGKSRRVMQRTFSSQSRQNVTQALPELQLGNAIIKPSRYVQNNQFSPLKKYPLVEQFRYPLWQAKPVEPQQGVKLEGASSNFISPQPGNIYIPLGKQEPGLYLVEAMVGGYRATTVVFVSDTVALSKVSGNELLVWTAGKKQGEAKTGSEILWTDGLGVMTRGVTDGSGTLQLQHISPERSYILGKDAEGGVFVSENFFYESEIYNTRLYIFTDRPLYRAGDRVDVKVMGREFHDPLHSSPIVSAPAKLSVLDANGSLLQTVNVTLDARNGGQGSFRLPENAVAGGYELRLAYRKQVYSSSFRVANYIKPHFEIGLALDKKEFKTGEAVSGKLQLLYPDGEPVKNARVQLSLRAQQLSMVGNDLRYAGRFPVSLEGSETVSDDNGHVALNLPAADKPSRYLLTVSASDGAAYRVTTTKEILIERGLAHYSLSTAAQYSNSGESVVFRYAALESSKQVPVTYEWLRLEDRTSHSGELQSGGKSFTVNFAKPGNYNLTLRDKDGLILAGLSHAVSGKGSTSHTGTVDIVADKTLYQPGETAKMLITFPEPIDEALLTLERDRVEQQSLLSHPANWLTLQRLNDTQYEARVPVSNSFAPNITFSVLYTRNGQYSFQNAGIKVAVPQLDIRVKTDKTHYQPGELVNVELTSSLKGKPVSAQLTVGVVDEMIYALQPEIAPNIGKFFYPLGRNNVRTSSSLSFISYDQALSSEPVAPGATNRSERRVKMLERPRREEVDTAAWMPSLTTDKQGKAYFTFLMPDSLTRWRITARGMNGDGLVGQGRAYLRSEKSLYMKWSMPTVYRMGDKPAAGLFIFSQQDNEPVALVTKFAGAEMRQTLTLHKGANYISLTQNIQQSGLLSAELQQNGQVQDSISTKLSFVDNSWPVEQQKNVMFGGGDNALTLPEQASNIRLQSSETPQEIFRNNLDALVDEPWGGVINTGSRLIPLSLAWRSLADHQSAAANDIRQMIQDNRLRLMQLAGPGARFTWWGEDGNGDAFLTAWAWYADWQASQALGVTQQPEYWQHMLDSYAEQADNMPLLHRALVLAWAQEMNLPCKTLLKGLDEAIARRGTKTKDFSEADTSDINDSMILDTPESPLADAVANVLTMTLLKKAQLKSTVMPQVQQYAWDKAANSNQPLAHTVVLLNSGGDATQAAAILSGLTAEQSTIERALAMNWLAKYMATMPPVVLPAPAGAWAKHKLTGGGEYWRWVGQGVPDILSFGDELSPQNVQVRWREPAKTAQQSNIPVTVERQLYRLIPGEEEMSFTLQPVTSNEIDSDALYLDEITLTSEQDAVLRYGQVEVPLPPGADVERTTWGISVNKPNAAKQQGQLLEKARNEMGELAYMVPVKELTGTVTFRHLLRFSQKGQFVLPPARYVRSYAPAQQSVAPGSEWIGMQVK
>NC_008253.1|WP_001104799.1|2365196_2366846_-|YfaQ-family-protein
MNWYRIVWLLALVTLPTLAEETPLQLALRGAQHDQLYQLSSSGVTKVSVLPDTLTTPLGSLWKLYIYAWLEDTHQPEQPYQCRGNSPEEVYCCQAGESITRDSALVRSCGLYFAPQRLHIGADMWGQYWQQRQAPAWLASLTTLKPETSVTVKSLLDSLATLPAQNKAQEVLLDVVLDEAKIGVASMLGSRVRVKTWSWFADDKQEIRQGGFAGWLTDGTPLWVTGSGTSKTVLTRYATALNRVLPVPTQVASGQCVLVDLFARYPLKKVTEEKSTTAVKPGVLNGRYRVTFANGNHMTFVSHGETTLLTVKGKLKLQSHLDREEYVARVLDREAKSTPPEAAKAMTVAIRTYLQQNADRDGDCLSIPDSSATQRVSASPATVGARTMTAWTQDLIYAGDPVHYHGSRVTEGTLSWRHATAQAGQGERYDQILAFAYPDNNLSRWGAPRSTCQLLPKAKAWLAKKMPQWRRILQGETGYNEPDVFAVCRLISGFPYTDRQQKRLFIRNFFTLQDRLDLTHEYLHLAFDGYPTGLDENYIETLTRQLLMD
>NC_008253.1|WP_001225875.1|2364415_2365192_-|YfaP-family-protein
MRKIFLPLLLVALSPVAHSEGVQEVEIDAPLSGWHPAEGEDASFSQTINYPASSVNMADDQNISAQIRGKIKNYAAAGKVQQGRLVVNGASMPQRIESDGSFARPYIFTEGSNSVQVISPDGQSRQKMQFYSTLGAGAIRARLRLVLSWDTDNTDLDLHVVTPDGEHAWYGNTVLKNSGALDMDVTTGYGPEIFAMPAPVHGRYQVYINYYGGRSETELTTAQLTLITDEGSVNEKQETFIVPMRNAGELTLVKSFDW
>NC_008253.1|WP_000786514.1|2363157_2364342_+|acetyl-CoA-acetyltransferase
MKNCVIVSAVRTAIGCFNGSLASTSAIDLGATVIKAAIERAKIDSLHIDEVIMGNVLQAGLGQNPARQALLKSGLAETVCGFTVNKVCGSGLKSVALATQAIQAGQAQSIVAGGMENMSLAPYLLDAKARSGYRLGDGQVYDVILRDGLMCATHGYHMGITAENVAKEYGITREMQDELALHSQRKAAAAIESGAFTAEIVPVNVVTRKKTFVFSQDEFPKADSTTEALGALRPAFDKAGTVTAGNASGINDGAAALVIMEESAALAAGLNPLARIKSYASGGVPPALMGMGPVPATQKALQLAGLQLADIDLIEANEAFAAQFLAVGKTLGFEPEKVNVNGGAIALGHPIGASGARILVTLLHAMQARDKTLGLATLCIGGGQGIAMVIERLN
>NC_008253.1|WP_000332036.1|2384392_2385523_+|ribonucleotide-diphosphate-reductase-subunit-beta
MAYTTFSQTKNDQLKEPMFFGQPVNVARYDQQKYDIFEKLIEKQLSFFWRPEEVDVSRDRIDYQALPEHEKHIFISNLKYQTLLDSIQGRSPNVALLPLISIPELETWVETWAFSETIHSRSYTHIIRNIVNDPSVVFDDIVTNEQIQKRAEGISSYYDELIEMTSYWHLLGEGTHTVNGKTVTVSLRELKKKLYLCLMSVNALEAIRFYVSFACSFAFAERELMEGNAKIIRLIARDEALHLTGTQHMLNLLRSGADDPEMAEIAEECKQECYDLFVQAAQQEKDWADYLFRDGSMIGLNKDILCQYVEYITNIRMQAVGLDLPFQTRSNPIPWINTWLVSDNVQVAPQEVEVSSYLVGQIDAEVDTDDLSNFQL
>NC_008253.1|WP_000135041.1|2385522_2385777_+|ferredoxin-like-diferric-tyrosyl-radical-cofactor-maintenance-protein-YfaE
MARVTLRITGTQLLCQDEHPSLLAALESHNVAVEYQCREGYCGSCRTRLVAGQVDWIAEPLAFIQPGKILPCCCRAKGDIEIEM
>NC_008253.1|WP_000301031.1|2385830_2386481_-|lipopolysaccharide-kinase-InaA
MAVSAKHDEFNHWWATEGDWVEEPNYRRNGMSGVQCVERNGKKLYVKRMTHHLFHSVRYPFGRPTIVREVAVIKELERAGVIVPKIVFGEAVKIEGEWRALLVTEDMAGFISIADWYARHAVSPYSDEVRQAMLKAVALAFKKMHSVNRQHGCCYVRHIYVKTEGKAEAGFLDLEKSRRRLRRDKAINHDFRQLEKYLEPIPKADWEQVKAYYYAM
>NC_008253.1|WP_000779093.1|2386683_2387760_-|glycerophosphodiester-phosphodiesterase
MKLTLKNLSMAIMMSTIVMGSSAMAADSNEKIVIAHRGASGYLPEHTLPAKAMAYAQGADYLEQDLVMTKDDHLVVLHDHYLDRVTDVADRFPDRARKDGRYYAIDFTLDEIKSLKFTEGFDIENGKKVQTYPGRFPMGKSDFRVHTFEEEIEFVQGLNHSTGKNIGIYPEIKAPWFHHQEGKDIAAKTLEVLKKYGYTGKDDKVYLQCFDADELKRIKNVLEPKMGMDLNLVQLIAYTDWNETQQKQPDGSWVNYNYDWMFKPGAMKQVAEYADGIGPDYHMLIEETSQPGNIKLTGMVQDAQQNKLVVHPYTVRSDKLPEYTTDVNQLYDALYNKAGVNGLFTDFPDKAVKFLNKE
>NC_008253.1|WP_000948732.1|2387764_2389123_-|glycerol-3-phosphate-transporter
MLSIFKPAPHKARLPAAEIDPTYRRLRWQIFLGIFFGYAAYYLVRKNFALAMPYLVEQGFSRGDLGFALSGISIAYGFSKFIMGSVSDRSNPRVFLPAGLILAAAVMLFMGFVPWATSSIAVMFVLLFLCGWFQGMGWPPCGRTMVHWWSQKERGGIVSVWNCAHNVGGGIPPLLFLLGMAWFNDWHAALYMPAFCAILVALFAFAMMRDTPQSCGLPPIEEYKNDYPDDYNEKAEQELTAKQIFMQYVLPNKLLWYIAIANVFVYLLRYGILDWSPTYLKEVKHFALDKSSWAYFLYEYAGIPGTLLCGWMSDKVFRGNRGATGVFFMTLVTIATIVYWMNPAGNPTVDMICMIVIGFLIYGPVMLIGLHALELAPKKAAGTAAGFTGLFGYLGGSVAASAIVGYTVDFFGWDGGFMVMIGGSILAVILLIVVMIGEKRRHEQLLQKRNGG
>NC_008253.1|WP_000857237.1|2389395_2391024_+|anaerobic-glycerol-3-phosphate-dehydrogenase-subunit-A
MKTRDSQSSDVIIIGGGATGAGIARDCALRGLRVILVERHDIATGATGRNHGLLHSGARYAVTDAESARECISENQILKRIARHCVEPTNGLFITLPEDDLSFQATFIRACEEAGISAEAIDPQQARIIEPAVNPALIGAVKVPDGTVDPFRLTAANMLDAKEHGAVILTAHEVTGLIREGATVCGVHVRNHLTGETQALHAPVVVNAAGIWGQHIAEYADLRIRMFPAKGSLLIMDHRINQHVINRCRKPSDADILVPGDTISLIGTTSLRIDYNEIDDNRVTAEEVDILLREGEKLAPVMAKTRILRAYSGVRPLVASDDDPSGRNVSRGIVLLDHAERDGLDGFITITGGKLMTYRLMAEWATDAVCRKLGNSRPCTTADLALPGSQEPAEATLRKVISLPAPLRGSAVYRHGDRTPAWLSEGRLHRSLVCECEAVTAGEVQYAVENLNVNSLLDLRRRTRVGMGTCQGELCACRAAGLLQRFNVTTSAQSIEQLSTFLNERWKGVQPIAWGDALRESEFTRWVYQGLCGLEKEQKDAL
>NC_008253.1|WP_001000377.1|2392269_2393460_+|anaerobic-glycerol-3-phosphate-dehydrogenase-subunit-C
MNDTSFENCIKCTVCTTACPVSRVNPGYPGPKQAGPDGERLRLKDGALYDEALKYCINCKRCEVACPSDVKIGDIIQRARAKYDTTRPSLRNFVLSHTDLMGSVSTPFAPIVNTATSLKPVRQLLDAALKIDHRRTLPKYSFGTFRRWYRSVAAQQAQYKDQVAFFHGCFVNYNHPQLGKDLIKVLNAMGTGVQLLSKEKCCGVPLIANGFTDKARKQAITNVESIREAVGVKGIPVIATSSTCTFALRDEYPEVLNVDNKGLRDHIELATRWLWRKLDEGKTLPLKPLPLKVVYHTPCHMEKMGWTLYTLELLRKIPGLELTVLDSQCCGIAGTYGFKKENYPTSQAIGAPLFRQIEESGADLVVTDCETCKWQIEMSTSLRCEHPITLLAQALA
>NC_008253.1|WP_000140537.1|2393652_2394612_+|ISNCY-family-transposase
MTESTTSSPHDAVFKTFMFSPDTARDFLEIHLPEPLRKLCNLQTLRLEPTSFIEKSLRAYYSDVLWSVETSEGDGYIYCVIEHQSSAEKNMAFRLMRYATAAMQRHLDKGYDRVPLVVPLLFYHGETSPYPYSLNWLDEFDDPQLARQLYTEAFPLVDITIVPDDEIMQHRRIALLELIQKHIRDRDLIGMVDRITTLLVRGFTNDSQLQTLFNYLLQCGDTSRFTRFIQEIAERSPLQKERLMTIAERLRQEGHQIGWQEGKIEGWQEGKLEGLQKGKVEGMHEQAIKIALRMLEQGFEREIVLATTQLTDADIPNCY
>NC_008253.1|WP_000150339.1|2394624_2394810_+|hypothetical-protein
MTIAERLRQEGHQIGWQEGKLEGMHEQAIKIALRMLEQGIDRDQVLAATQLSEADLAANNH
>NC_008253.1|WP_000992978.1|2394850_2395654_-|2-keto-3-deoxy-L-rhamnonate-aldolase
MNALLTNPFKERLRKGEVQIGLWLSSTTAYMAEIAATSGYDWLLIDGEHAPNTIQDLYHQLQAVAPYASHPVIRPVEGSKPLIKQVLDIGAQTLLIPMVDTADQARQVVSATRYPPYGERGVGASVARAARWGRIENYMAQVNDSLCLLVQVESKTALDNLDEILDVEGIDGVFIGPADLSASLGYPDNAGHQEVQRIIETSIRRIRAAGKAAGFLAVAPDMAQQCLAWGTNFVAVGVDTMLYSDALDQRLAMFKSGKNGPRVKGSY

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Crispr_ID: NC_008253_5

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_008253_5

4233264-4233465

Orphan

Consensus_repeat	Method
GTAGACCGGATAAGGCGTTCACGCCGCATCCGGCAA	PILER-CR

2 spacers

The CRISPR arrays of NC_008253_5

>merge|NC_008253|5|4233264-4233465|PILER-CR
CGCATCCGGCAATTGGTGCACGATGCCTGATGCGACGCTGGCGCGTCTTATCAGGCCTACATTGGTGCCGGATCGGTAGACCGGATAAGGCGTTCACGCCGTATCCGGCATACAGTGCCCGATGCGACGCTGCCGCGTCTTATCGGGCCTACAAAAGTTCTGAACCGTAGACCGGATAAGGCGTTCACGCCGCATCCGGCAA

>NC_008253|5|1|4233264-4233465|PILER-CR
CGCATCCGGCAATTGGTGCACGATGCCTGATGCGAC	GCTGGCGCGTCTTATCAGGCCTACATTGGTGCCGGATCGGTAGACCGGATAAGGCGTTCACGC
CGTATCCGGCATACAGTGCCCGATGCGACGCTGCCG	CGTCTTATCGGGCCTACAAAAGTTCTGAACCGTAGACCGGATAAGGCGTTCACGCC
GCATCCGGCAA

Protein	Signature genes	Signature genes Name	Protein_function
NC_008253.1\|WP_000545665.1\|4239005_4240457_+\|Trk-system-potassium-transporter-TrkH	unknown	unknown	gnl\|CDD\|182698
NC_008253.1\|WP_000444545.1\|4237021_4238353_+\|Xaa-Pro-dipeptidase	unknown	unknown	gnl\|CDD\|237444
NC_008253.1\|WP_000907613.1\|4246598_4247126_-\|molybdopterin-guanine-dinucleotide-biosynthesis-protein-B	unknown	unknown	gnl\|CDD\|236750
NC_008253.1\|WP_001298601.1\|4232486_4233188_+\|NAD(P)H-flavin-reductase	unknown	unknown	gnl\|CDD\|236142
NC_008253.1\|WP_001052191.1\|4247107_4247692_-\|molybdenum-cofactor-guanylyltransferase-MobA	unknown	unknown	gnl\|CDD\|234725
NC_008253.1\|WP_001298607.1\|4229510_4230293_+\|3'-5'-ssDNA/RNA-exonuclease-TatD	unknown	unknown	gnl\|CDD\|182449
NC_008253.1\|WP_001065498.1\|4248107_4249094_+\|stress-response-kinase-SrkA	unknown	unknown	gnl\|CDD\|236974
NC_008253.1\|WP_000109949.1\|4228692_4229469_+\|Sec-independent-protein-translocase-subunit-TatC	unknown	unknown	gnl\|CDD\|182840
NC_008253.1\|WP_001295263.1\|4247761_4248031_+\|YihD-family-protein	unknown	unknown	gnl\|CDD\|368826
NC_008253.1\|WP_000438744.1\|4233469_4234633_-\|acetyl-CoA-C-acyltransferase-FadA	unknown	unknown	gnl\|CDD\|181592
NC_008253.1\|WP_000187545.1\|4226182_4227823_+\|ubiquinone-biosynthesis-regulatory-protein-kinase-UbiB	unknown	unknown	gnl\|CDD\|235310
NC_008253.1\|WP_000227959.1\|4224811_4225567_+\|bifunctional-demethylmenaquinone-methyltransferase/2-methoxy-6-polyprenyl-1,4-benzoquinol-methylase-UbiE	unknown	unknown	gnl\|CDD\|234689
NC_008253.1\|WP_001335246.1\|4238352_4238967_+\|IMPACT-family-protein	unknown	unknown	gnl\|CDD\|183205
NC_008253.1\|WP_001192400.1\|4230289_4230778_-\|transcription/translation-regulatory-transformer-protein-RfaH	unknown	unknown	gnl\|CDD\|181611
NC_008253.1\|WP_001295260.1\|4227901_4228171_+\|Sec-independent-protein-translocase-subunit-TatA	unknown	unknown	gnl\|CDD\|179592
NC_008253.1\|WP_000459600.1\|4228174_4228690_+\|Sec-independent-protein-translocase-subunit-TatB	unknown	unknown	gnl\|CDD\|179334
NC_008253.1\|WP_000965960.1\|4234642_4236832_-\|fatty-acid-oxidation-complex-subunit-alpha-FadB	unknown	unknown	gnl\|CDD\|183293
NC_008253.1\|WP_011579293.1\|4225580_4226186_+\|ubiquinone-biosynthesis-protein-UbiJ	unknown	unknown	gnl\|CDD\|225706
NC_008253.1\|WP_000853963.1\|4240468_4241014_+\|menaquinone-dependent-protoporphyrinogen-IX-dehydrogenase	unknown	unknown	gnl\|CDD\|182966
NC_008253.1\|WP_000339823.1\|4230944_4232441_+\|4-hydroxy-3-polyprenylbenzoate-decarboxylase	unknown	unknown	gnl\|CDD\|236796

Protein	Function_ID	Function_description	E-value
NC_008253.1\|WP_000545665.1\|4239005_4240457_+\|Trk-system-potassium-transporter-TrkH	gnl\|CDD\|182698	PRK10750, PRK10750, Trk system potassium transporter TrkH.	0
NC_008253.1\|WP_000444545.1\|4237021_4238353_+\|Xaa-Pro-dipeptidase	gnl\|CDD\|237444	PRK13607, PRK13607, proline dipeptidase; Provisional.	0
NC_008253.1\|WP_000907613.1\|4246598_4247126_-\|molybdopterin-guanine-dinucleotide-biosynthesis-protein-B	gnl\|CDD\|236750	PRK10751, PRK10751, molybdopterin-guanine dinucleotide biosynthesis protein B; Provisional.	1.11706e-122
NC_008253.1\|WP_001298601.1\|4232486_4233188_+\|NAD(P)H-flavin-reductase	gnl\|CDD\|236142	PRK08051, fre, FMN reductase; Validated.	3.9413e-172
NC_008253.1\|WP_001052191.1\|4247107_4247692_-\|molybdenum-cofactor-guanylyltransferase-MobA	gnl\|CDD\|234725	PRK00317, mobA, molybdopterin-guanine dinucleotide biosynthesis protein MobA; Reviewed.	4.97316e-99
NC_008253.1\|WP_001298607.1\|4229510_4230293_+\|3'-5'-ssDNA/RNA-exonuclease-TatD	gnl\|CDD\|182449	PRK10425, PRK10425, 3'-5' ssDNA/RNA exonuclease TatD.	0
NC_008253.1\|WP_001065498.1\|4248107_4249094_+\|stress-response-kinase-SrkA	gnl\|CDD\|236974	PRK11768, PRK11768, serine/threonine protein kinase.	0
NC_008253.1\|WP_000109949.1\|4228692_4229469_+\|Sec-independent-protein-translocase-subunit-TatC	gnl\|CDD\|182840	PRK10921, PRK10921, Sec-independent protein translocase subunit TatC.	0
NC_008253.1\|WP_001295263.1\|4247761_4248031_+\|YihD-family-protein	gnl\|CDD\|368826	pfam06288, DUF1040, Protein of unknown function (DUF1040). This family consists of several bacterial YihD proteins of unknown function.	4.97051e-53
NC_008253.1\|WP_000438744.1\|4233469_4234633_-\|acetyl-CoA-C-acyltransferase-FadA	gnl\|CDD\|181592	PRK08947, fadA, 3-ketoacyl-CoA thiolase; Reviewed.	0
NC_008253.1\|WP_000187545.1\|4226182_4227823_+\|ubiquinone-biosynthesis-regulatory-protein-kinase-UbiB	gnl\|CDD\|235310	PRK04750, ubiB, putative ubiquinone biosynthesis protein UbiB; Reviewed.	0
NC_008253.1\|WP_000227959.1\|4224811_4225567_+\|bifunctional-demethylmenaquinone-methyltransferase/2-methoxy-6-polyprenyl-1,4-benzoquinol-methylase-UbiE	gnl\|CDD\|234689	PRK00216, ubiE, bifunctional demethylmenaquinone methyltransferase/2-methoxy-6-polyprenyl-1,4-benzoquinol methylase UbiE.	1.2623e-150
NC_008253.1\|WP_001335246.1\|4238352_4238967_+\|IMPACT-family-protein	gnl\|CDD\|183205	PRK11568, PRK11568, IMPACT family protein.	4.48916e-152
NC_008253.1\|WP_001192400.1\|4230289_4230778_-\|transcription/translation-regulatory-transformer-protein-RfaH	gnl\|CDD\|181611	PRK09014, rfaH, transcription/translation regulatory transformer protein RfaH.	7.04858e-121
NC_008253.1\|WP_001295260.1\|4227901_4228171_+\|Sec-independent-protein-translocase-subunit-TatA	gnl\|CDD\|179592	PRK03554, tatA, Sec-independent protein translocase subunit TatA.	6.75664e-44
NC_008253.1\|WP_000459600.1\|4228174_4228690_+\|Sec-independent-protein-translocase-subunit-TatB	gnl\|CDD\|179334	PRK01770, PRK01770, Sec-independent protein translocase subunit TatB.	4.56825e-89
NC_008253.1\|WP_000965960.1\|4234642_4236832_-\|fatty-acid-oxidation-complex-subunit-alpha-FadB	gnl\|CDD\|183293	PRK11730, fadB, fatty acid oxidation complex subunit alpha FadB.	0
NC_008253.1\|WP_011579293.1\|4225580_4226186_+\|ubiquinone-biosynthesis-protein-UbiJ	gnl\|CDD\|225706	COG3165, COG3165, Uncharacterized protein conserved in bacteria [Function unknown].	1.51432e-94
NC_008253.1\|WP_000853963.1\|4240468_4241014_+\|menaquinone-dependent-protoporphyrinogen-IX-dehydrogenase	gnl\|CDD\|182966	PRK11104, hemG, menaquinone-dependent protoporphyrinogen IX dehydrogenase.	6.96931e-127
NC_008253.1\|WP_000339823.1\|4230944_4232441_+\|4-hydroxy-3-polyprenylbenzoate-decarboxylase	gnl\|CDD\|236796	PRK10922, PRK10922, 4-hydroxy-3-polyprenylbenzoate decarboxylase.	0

>NC_008253.1|WP_001298601.1|4232486_4233188_+|NAD(P)H-flavin-reductase
MTTLSCKVTSVEAITDTVYRVRIVPDAAFSFRAGQYLMVVMDERDKRPFSMASTPDEKGFIELHIGASEINLYAKAVMDRILKDHQIVVDIPHGEAWLRDDEERPMILIAGGTGFSYARSILLTALARNPNRDITIYWGGREEQHLYDLCELEALSLKHPGLQVVPVVEQPEAGWRGRTGTVLTAVLQDHGTLTEHDIYIAGRFEMAKIARDLFCSERNAREDRLFGDAFAFI
>NC_008253.1|WP_000339823.1|4230944_4232441_+|4-hydroxy-3-polyprenylbenzoate-decarboxylase
MDAMKYNDLRDFLTLLEQQGELKRITLPVDPHLEITEIWLDRTLRAGGPALLFENPKGYSMPVLCNLFGTPKRVAMGMGQEDVSALREVGKLLAFLKEPEPPKGFRDLFDKLPQFKQVLNMPTKRLRGAPCQQKIVSGDDVDLNRIPIMTCWPEDAAPLITWGLTVTRGPHKERQNLGIYRQQLIGKNKLIMRWLSHRGGALDYQEWCAAHPGERFPVSVALGADPATILGAVTPVPDTLSEYAFAGLLRGTKTEVVKCISNDLEVPASAEIVLEGYIEQGETAPEGPYGDHTGYYNEVDSFPVFTVTHITQREDAIYHSTYTGRPPDEPAVLGVALNEVFVPILQKQFPEIVDFYLPPEGCSYRLAVVTIKKQYAGHAKRVMMGVWSFLRQFMYTKFVIVCDDDVNARDWNDVIWAITTRMDPARDTVLVENTPIDYLDFASPVSGLGSKMGLDATNKWPGETQREWGRPIKKDPDVVAHIDAIWDELAIFNNGKSA
>NC_008253.1|WP_001192400.1|4230289_4230778_-|transcription/translation-regulatory-transformer-protein-RfaH
MQSWYLLYCKRGQLQRAQEHLERQAVNCLAPMITLEKIVRGKRTAVSEPLFPNYLFVEFDPEVIHTTTINATRGVSHFVRFGASPAIVPSAVIHQLSVYKPKDIVDPSTPYPGDKVIITEGAFEGFQAIFTEPDGEARSMLLLNLINKEIKHSVKNTEFRKL
>NC_008253.1|WP_001298607.1|4229510_4230293_+|3'-5'-ssDNA/RNA-exonuclease-TatD
MFDIGVNLTSSQFAKDRDDVVARAFDAGVNGLLITGTNLRESQQAQKLARQYSSCWSTAGVHPHDSSQWQAVTEEAIIELAAQPEVVAIGECGLDFNRNFSTPEEQELAFVAQLRIAAELNMPVFMHCRDAHERFMTLLEPWLDKLPGAVLHCFTGTREEMQACVARGIYIGITGWVCDERRGLELRELLPLIPAEKLLIETDAPYLLPRDLTPKPSSRRNEPAHLPHILQRIAHWRGEDAAWLAATTDANVKTLFGIAF
>NC_008253.1|WP_000109949.1|4228692_4229469_+|Sec-independent-protein-translocase-subunit-TatC
MSVEDTQPLITHLIELRKRLLNCIISVIVIFLCLVYFANDIYHLVSAPLIKQLPQGSTMIATDVASPFFTPIKLTFMVSLILSAPVILYQVWAFIAPALYKHERRLVVPLLVSSSLLFYIGMAFAYFVVFPLAFGFLANTAPEGVQVSTDIASYLSFVMALFMAFGVSFEVPVAIVLLCWMGITSPEDLRKKRPYVLVGAFVVGMLLTPPDVFSQTLLAIPMYCLFEIGVFFSRFYVGKGRNREEENDAEAESEKTEE
>NC_008253.1|WP_000459600.1|4228174_4228690_+|Sec-independent-protein-translocase-subunit-TatB
MFDIGFSELLLVFIIGLVVLGPQRLPVAVKTVAGWIRALRSLATTVQNELTQELKLQEFQDSLKKVEKASLTNLTPELKASMDELRQAAESMKRSYVANDPEKASDEAHTIHNPVVKDNETAHEGVTPAAAQTQASSPEQKPETTPEPVVKPAADAEPKTAAPSPSSSDKP
>NC_008253.1|WP_001295260.1|4227901_4228171_+|Sec-independent-protein-translocase-subunit-TatA
MGGISIWQLLIIAVIVVLLFGTKKLGSIGSDLGASIKGFKKAMSDDEPKQDKTSQDADFTAKTIADKQADTNQEQAKTEDAKRHDKEQV
>NC_008253.1|WP_000187545.1|4226182_4227823_+|ubiquinone-biosynthesis-regulatory-protein-kinase-UbiB
MTPGEVRRLYFIIRTFLSYGLDELIPKMRITLPLRLWRYSLFWMPNRHKDKPLGERLRLALQELGPVWIKFGQMLSTRRDLFPPHIADQLALLQDKVAPFDGKLAKQQIEAAMGGLPVEAWFDDFEIKPLASASIAQVHTARLKSNGKEVVIKVIRPDILPVIKADLKLIYRLARWVPRLLPDGRRLRPTEVVREYEKTLIDELNLLRESANAIQLRRNFEDSPMLYIPEVYPDYCSEGMMVMERIYGIPVSDVATLEKNGTNMKLLAERGVQVFFTQVFRDSFFHADMHPGNIFVSYEHPENPKYIGIDCGIVGSLNKEDKRYLAENFIAFFNRDYRKVAELHVDSGWVPPDTNVEEFEFAIRTVCEPIFEKPLAEISFGHVLLNLFNTARRFNMEVQPQLVLLQKTLLYVEGVGRQLYPQLDLWKTAKPFLESWIKDQVGIPALVRAFKEKAPFWVEKMPELPELVYDSLRQGKYLQHSVDKIARELQSNHVRQGQSRYFLGIGATLVLSGTFLLVSRPEWGLMPGWLMAGGLIAWFVGWRKTR
>NC_008253.1|WP_011579293.1|4225580_4226186_+|ubiquinone-biosynthesis-protein-UbiJ
MPFKPLVTAGIESLLNTFLYRSPALKTARSRLLGKVLRVEVKGFSTSLILVFSERQVDVLGEWAGDADCTVIAYASVLPKLRDRQQLAALIRSGELEVQGDIQVVQNFVALADLAEFDPAELLAPYTGDIAAEGISKALRGGTKFLHHGIKRQQRYVAEAITEEWRMAPGPLEVAWFAEETAAVERAVDALTKRLEKLEAK
>NC_008253.1|WP_000227959.1|4224811_4225567_+|bifunctional-demethylmenaquinone-methyltransferase/2-methoxy-6-polyprenyl-1,4-benzoquinol-methylase-UbiE
MVDKSQETTHFGFQTVAKEQKADMVAHVFHSVASKYDVMNDLMSFGIHRLWKRFTIDCSGVRRGQTVLDLAGGTGDLTAKFSRLVGETGKVVLADINESMLKMGREKLRNIGVIGNVEYVQANAEALPFPDNTFDCITISFGLRNVTDKDKALRSMYRVLKPGGRLLVLEFSKPIIEPLSKAYDAYSFHVLPRIGSLVANDADSYRYLAESIRMHPDQDTLKTMMQDAGFESVDYYNLTAGVVALHRGYKF
>NC_008253.1|WP_000438744.1|4233469_4234633_-|acetyl-CoA-C-acyltransferase-FadA
MEQVVIVDAIRTPMGRSKGGAFRNVRAEDLSAHLMRSLLARNPALEAAALDDIYWGCVQQTLEQGFNIARNAALLAEVPHSVPAVTVNRLCGSSMQALHDAARMIMTGDAQACLVGGVEHMGHVPMSHGVDFHPGLSRNVAKAAGMMGLTAEMLARMHGISREMQDAFAARSHARAWAATQSGAFKNEIIPTGGHDADGVLKQFNYDEVIRPETTVEALATLRPAFDPVSGTVTAGTSSALSDGAAAMLVMSESRARDLGLKPRACVRSMAVVGCDPSIMGYGPVPASKLALKKAGLSASDIGVFEMNEAFAAQILPCIKDLGLMEQIDEKINLNGGAIALGHPLGCSGARISTTLLNLMEHKDVQFGLATMCIGLGQGIATVFERV
>NC_008253.1|WP_000965960.1|4234642_4236832_-|fatty-acid-oxidation-complex-subunit-alpha-FadB
MLYKGDTLYLDWLEDGIAELVFDAPGSVNKLDTATVASLGEAIGVLEQQSDLKGLLLRSNKAAFIVGADITEFLSLFLVPEEQLSQWLHFANSVFNRLEDLPVPTIAAVNGYALGGGCECVLATDYRLATPDLRIGLPETKLGIMPGFGGSVRMPRMLGADSALEIIAAGKDVGADQALKIGLVDGVVKAEKLVEGAMAILRQAINGDLDWKAKRQPKLEPLKLSKIEAAMSFTIAKGMVAQTAGKHYPAPITAVKTIEAAARFGREEALNLENKSFVPLAHTNEARALVGIFLNDQYVKGKAKKLTKDVETPKQAAVLGAGIMGGGIAYQSAWKGVPVVMKDINDKSLTLGMTEAAKLLNKQLERGKIDGLKLAGVISTIHPTLDYAGFDRVDVVVEAVVENPKVKKAVLAETEQKVRPDTVLASNTSTIPISELANALERPENFCGMHFFNPVHRMPLVEIIRGEKSSDETIAKVVAWASKMGKTPIVVNDCPGFFVNRVLFPYFAGFSQLLRDGADFRKIDKVMEKQFGWPMGPAYLLDVVGIDTAHHAQAVMAAGFPQRMQKDYRDAIDALFNANRFGQKNGLGFWRYKEDSKGKPKKEEDVVVDDLLAKVSQPKRDFSEEEIIARMMIPMVNEVVRCLEEGIIATPAEADMALVYGLGFPPFHGGAFRWLDTLGSAKYLDMAQQYQHLGPLYEVPEGMRNKARHNEPYYPPVEPARPVGDLKTA
>NC_008253.1|WP_000444545.1|4237021_4238353_+|Xaa-Pro-dipeptidase
MESLASLYKNHIATLQERTRDALARFKLDALLIHSGELFNVFLDDHPYPFKVNPQFKAWVPVTQVPNCWLLVDGVNKPKLWFYLPVDYWHNVEPLPNSFWTEDVEVIALPKADGIGSLLPAARGNIGYIGPVPERALQLGIEASNINPKGVIDYLHYYRSFKTEYELACMREAQKMAVNGHRAAEEAFRSGMSEFDINIAYLTATGHRDTDVPYSNIVALNEHAAVLHYTKLDHQAPEEMRSFLLDAGAEYNGYAADLTRTWSAKSDNDYAQLVKDVNDEQLALIATMKAGVSYVDYHIQFHQRIAKLLRKHQIITDMSEEAMVENDLTGPFMPHGIGHPLGLQVHDVAGFMQDDSGTHLAAPAKYPYLRCTRILQPGMVLTIEPGIYFIESLLAPWREGQFSKHFNWQKIEALKPFGGIRIEDNVVIHENNVENMTRDLKLA
>NC_008253.1|WP_001335246.1|4238352_4238967_+|IMPACT-family-protein
MESWLIPAAPVMVVEEIKKSRFITLLAHTDGVEAAKAFVESVRAEHPDARHHCVAWVAGAPDDSQQLGFSDDGEPAGTAGKPMLAQLMGSGVGEITAVVVRYYGGILLGTGGLVKAYGGGVNQALRQLTTQRKTPLTEYTLQCEYSQLTGIEALLGQCDGKIINSDYQAFVLLRVALPAAKVAEFSAKLADFSRGSLQLLAIEE
>NC_008253.1|WP_000545665.1|4239005_4240457_+|Trk-system-potassium-transporter-TrkH
MHFRAITRIVGLLVILFSGTMIIPGLVALIYRDGAGRAFTQTFFVALAIGSMLWWPNRKEKGELKSREGFLIVVLFWTVLGSVGALPFIFSESPNLTITDAFFESFSGLTTTGATTLVGLDSLPHAILFYRQMLQWFGGMGIIVLAVAILPILGVGGMQLYRAEMPGPLKDNKMRPRIAETAKTLWLIYVLLTVACALALWFAGMDAFDAIGHSFATIAIGGFSTHDASIGYFDSPTINTIIAIFLLISGCNYGLHFSLLSGRSLKVYWRDPEFRMFIGVQFSLVVICTLVLWFHNVYSSALMTINQAFFQVVSMATTAGFTTDSIARWPLFLPVLLLCSAFIGGCAGSTGGGLKVIRILLLFKQGNRELKRLVHPNAVYSIKLGNRALPERILEAVWGFFSAYALVFIVSMLAIIATGVDDFSAFASVVATLNNLGPGLGVVADNFTSMNPVAKWILIANMLFGRLEVFTLLVLFTPTFWRE
>NC_008253.1|WP_000853963.1|4240468_4241014_+|menaquinone-dependent-protoporphyrinogen-IX-dehydrogenase
MKTLILFSTRDGQTREIASYLASELKELGIQADVANVHRIEEPQWENYDRVVIGASIRYGHYHSAFQEFVKKHATRLNSMPSAFYSVNLVARKPEKRTPQTNSYARKFLMSSQWRPDRCAVIAGALRYPRYRWYDRFMIKLIMKMSGGETDTRKEVVYTDWEQVANFAREIAHLTDKPTLK
>NC_008253.1|WP_000907613.1|4246598_4247126_-|molybdopterin-guanine-dinucleotide-biosynthesis-protein-B
MAGKTMIPLLAFAAWSGTGKTTLLKKLIPALCARGIRPGLIKHTHHDMDVDKPGKDSYELRKAGAAQTIVASQQRWALMTETPDEEELDLHFLASRMDTSKLDLILVEGFKHEEIAKIVLFRDGAGHRPEELVIDRHVIAVASDVPLNLDVALLDINDVEGLADFVVEWMQKQDG
>NC_008253.1|WP_001052191.1|4247107_4247692_-|molybdenum-cofactor-guanylyltransferase-MobA
MNLMTTITGVVLAGGKARRMGGVDKGLLELNGKPLWQHVADALMTQLSHVVVNANRHQEIYQVSGLKVIEDSLADYPGPLAGMLSVMQQESGEWFLFCPCDTPYIPHDLASRLNHQRKDAPVVWVHDGERDHPTIALVNRAIEPLLLEYLQAGERRVMAFMRLAGGHAVDFSDRKEAFINVNTPEELARWQEKR
>NC_008253.1|WP_001295263.1|4247761_4248031_+|YihD-family-protein
MKCKRLNEVIELLQPAWQKEPDLNLLQFLQKLAKESGFDGELADLTDDILIYHLKMRDSAKDAVIPGLQKDYEEDFKTALLRARGVIKE
>NC_008253.1|WP_001065498.1|4248107_4249094_+|stress-response-kinase-SrkA
MNNSAFTFQTLHPDTIMDALFEHGIRVDSGLTPLNSYENRVYQFQDEDRRRFVVKFYRPERWTADQILEEHQFALQLVNDEVPVAAPVAFNGQTLLNHQGFYFAVFPSVGGRQFEADNIDQMEAVGRYLGRMHQTGRKQLFIHRPTIGLNEYLIEPRKLFEDATLIPSGLKAAFLKATDELIAAVTAHWREDFTVLRLHGDCHAGNILWRDGPMFVDLDDARNGPAVQDLWMLLNGDKAEQRMQLETIIEAYEEFSEFDTAEIGLIEPLRAMRLVYYLAWLMRRWADPAFPKNFPWLTGEDYWLRQTVTFIEQAKVLQEPPLQLTPMY

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Crispr_ID: NC_008253_6

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_008253_6

4293894-4294020

Orphan

Consensus_repeat	Method
GTAGGCCGGATAAGGCACTCGTGCCGCATCCGGCA	CRISPRCasFinder

1 spacers

The CRISPR arrays of NC_008253_6

>merge|NC_008253|6|4293894-4294020|CRISPRCasFinder
GTAGGCCGGATAAGGCACTCGTGCCGCATCCGGCAATCAATGCCTGATGCGACGCTGTCGCGTCTTATCAGGCCTACAACTATTGCCGACCTGTAGGCCGGATAAGGCACTTGTGCCGCATCCGGCA

>NC_008253|6|5|4293894-4294020|CRISPRCasFinder
GTAGGCCGGATAAGGCACTCGTGCCGCATCCGGCA	ATCAATGCCTGATGCGACGCTGTCGCGTCTTATCAGGCCTACAACTATTGCCGACCT
GTAGGCCGGATAAGGCACTTGTGCCGCATCCGGCA

Protein	Signature genes	Signature genes Name	Protein_function
NC_008253.1\|WP_001298699.1\|4294024_4295284_-\|L-rhamnose-isomerase	unknown	unknown	gnl\|CDD\|179217
NC_008253.1\|WP_000144094.1\|4295280_4296750_-\|rhamnulokinase	unknown	unknown	gnl\|CDD\|182609
NC_008253.1\|WP_001270236.1\|4302124_4302799_+\|6-N-hydroxylaminopurine-resistance-protein	unknown	unknown	gnl\|CDD\|183182
NC_008253.1\|WP_001296618.1\|4297857_4298796_+\|HTH-type-transcriptional-activator-RhaR	unknown	unknown	gnl\|CDD\|184091
NC_008253.1\|WP_000749943.1\|4291266_4292661_+\|carbohydrate-porin	unknown	unknown	gnl\|CDD\|374908
NC_008253.1\|WP_000829013.1\|4284509_4285145_-\|formate-dehydrogenase-cytochrome-b556-subunit	unknown	unknown	gnl\|CDD\|182608
NC_008253.1\|WP_000753582.1\|4289300_4290134_+\|formate-dehydrogenase-accessory-sulfurtransferase-FdhD	unknown	unknown	gnl\|CDD\|234823
NC_008253.1\|WP_000217156.1\|4297037_4297874_+\|HTH-type-transcriptional-activator-RhaS	unknown	unknown	gnl\|CDD\|184094
NC_008253.1\|WP_001179744.1\|4293025_4293850_-\|rhamnulose-1-phosphate-aldolase	unknown	unknown	gnl\|CDD\|179615
NC_008253.1\|WP_000331377.1\|4285141_4286044_-\|formate-dehydrogenase-O-subunit-beta	unknown	unknown	gnl\|CDD\|273705
NC_008253.1\|WP_000580417.1\|4302970_4304344_-\|envelope-stress-sensor-histidine-kinase-CpxA	unknown	unknown	gnl\|CDD\|236532
NC_008253.1\|WP_178278646.1\|4290162_4290846_+\|DUF3829-domain-containing-protein	unknown	unknown	gnl\|CDD\|372366
NC_008253.1\|WP_000063507.1\|4298792_4299827_-\|L-rhamnose/proton-symporter-RhaT	unknown	unknown	gnl\|CDD\|115061
NC_008253.1\|WP_001298592.1\|4283150_4283369_+\|CopG-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|279710
NC_008253.1\|WP_001033719.1\|4304340_4305039_-\|envelope-stress-response-regulator-transcription-factor-CpxR	unknown	unknown	gnl\|CDD\|182864
NC_008253.1\|WP_000619492.1\|4292701_4293016_-\|L-rhamnose-mutarotase	unknown	unknown	gnl\|CDD\|131674
NC_008253.1\|WP_000027720.1\|4283583_4284513_-\|formate-dehydrogenase-accessory-protein-FdhE	unknown	unknown	gnl\|CDD\|179595
NC_008253.1\|WP_077634631.1\|4286056_4289107_-\|formate-dehydrogenase-N-subunit-alpha	unknown	unknown	gnl\|CDD\|273689
NC_008253.1\|WP_001298417.1\|4300112_4300733_+\|superoxide-dismutase-[Mn]	unknown	unknown	gnl\|CDD\|182843
NC_008253.1\|WP_001166063.1\|4300992_4301976_+\|2-keto-3-deoxygluconate-transporter	unknown	unknown	gnl\|CDD\|273271

Protein	Function_ID	Function_description	E-value
NC_008253.1\|WP_001298699.1\|4294024_4295284_-\|L-rhamnose-isomerase	gnl\|CDD\|179217	PRK01076, PRK01076, L-rhamnose isomerase; Provisional.	0
NC_008253.1\|WP_000144094.1\|4295280_4296750_-\|rhamnulokinase	gnl\|CDD\|182609	PRK10640, rhaB, rhamnulokinase; Provisional.	0
NC_008253.1\|WP_001270236.1\|4302124_4302799_+\|6-N-hydroxylaminopurine-resistance-protein	gnl\|CDD\|183182	PRK11536, PRK11536, 6-N-hydroxylaminopurine resistance protein; Provisional.	4.41365e-179
NC_008253.1\|WP_001296618.1\|4297857_4298796_+\|HTH-type-transcriptional-activator-RhaR	gnl\|CDD\|184091	PRK13500, PRK13500, HTH-type transcriptional activator RhaR.	0
NC_008253.1\|WP_000749943.1\|4291266_4292661_+\|carbohydrate-porin	gnl\|CDD\|374908	pfam16966, Porin_8, Porin-like glycoporin RafY. This is a family of Gram-negative Gammaproteobacteria putative raffinose-like porins.	0
NC_008253.1\|WP_000829013.1\|4284509_4285145_-\|formate-dehydrogenase-cytochrome-b556-subunit	gnl\|CDD\|182608	PRK10639, PRK10639, formate dehydrogenase cytochrome b556 subunit.	6.79831e-145
NC_008253.1\|WP_000753582.1\|4289300_4290134_+\|formate-dehydrogenase-accessory-sulfurtransferase-FdhD	gnl\|CDD\|234823	PRK00724, PRK00724, formate dehydrogenase accessory sulfurtransferase FdhD.	1.63704e-160
NC_008253.1\|WP_000217156.1\|4297037_4297874_+\|HTH-type-transcriptional-activator-RhaS	gnl\|CDD\|184094	PRK13503, PRK13503, HTH-type transcriptional activator RhaS.	0
NC_008253.1\|WP_001179744.1\|4293025_4293850_-\|rhamnulose-1-phosphate-aldolase	gnl\|CDD\|179615	PRK03634, PRK03634, rhamnulose-1-phosphate aldolase; Provisional.	0
NC_008253.1\|WP_000331377.1\|4285141_4286044_-\|formate-dehydrogenase-O-subunit-beta	gnl\|CDD\|273705	TIGR01582, Formate_dehydrogenase_iron-sulfur_subunit, formate dehydrogenase, beta subunit, Fe-S containing. This model represents the beta subunit of the gamma-proteobacterial formate dehydrogenase. This subunit contains four 4Fe-4S clusters and is involved in transmitting electrons from the alpha subunit (TIGR01553) at the periplasmic space to the gamma subunit which spans the cytoplasmic membrane. In addition to the gamma proteobacteria, a sequence from Aquifex aolicus falls within the scope of this model. This appears to be the case for the alpha, gamma and epsilon (accessory protein TIGR01562) chains as well. [Energy metabolism, Anaerobic, Energy metabolism, Electron transport].	1.25079e-161
NC_008253.1\|WP_000580417.1\|4302970_4304344_-\|envelope-stress-sensor-histidine-kinase-CpxA	gnl\|CDD\|236532	PRK09470, cpxA, envelope stress sensor histidine kinase CpxA.	0
NC_008253.1\|WP_178278646.1\|4290162_4290846_+\|DUF3829-domain-containing-protein	gnl\|CDD\|372366	pfam12889, DUF3829, Protein of unknown function (DUF3829). This is a small family of proteins from several bacterial species, whose function is not known. It may, however, be related to the GvpL_GvpF family of proteins, pfam06386.	1.83732e-52
NC_008253.1\|WP_000063507.1\|4298792_4299827_-\|L-rhamnose/proton-symporter-RhaT	gnl\|CDD\|115061	pfam06379, RhaT, L-rhamnose-proton symport protein (RhaT). This family consists of several bacterial L-rhamnose-proton symport protein (RhaT) sequences.	0
NC_008253.1\|WP_001298592.1\|4283150_4283369_+\|CopG-family-transcriptional-regulator	gnl\|CDD\|279710	pfam01402, RHH_1, Ribbon-helix-helix protein, copG family. The structure of this protein repressor, which is the shortest reported to date and the first isolated from a plasmid, has a homodimeric ribbon-helix-helix arrangement. The helix-turn-helix-like structure is involved in dimerization and not DNA binding as might have been expected.	1.66689e-06
NC_008253.1\|WP_001033719.1\|4304340_4305039_-\|envelope-stress-response-regulator-transcription-factor-CpxR	gnl\|CDD\|182864	PRK10955, PRK10955, envelope stress response regulator transcription factor CpxR.	7.11209e-169
NC_008253.1\|WP_000619492.1\|4292701_4293016_-\|L-rhamnose-mutarotase	gnl\|CDD\|131674	TIGR02625, L-rhamnose_mutarotase, L-rhamnose mutarotase. Members of this protein family are rhamnose mutarotase from Escherichia coli, previously designated YiiL as an uncharacterized protein, and close homologs also associated with rhamnose dissimilation operons in other bacterial genomes. Mutarotase is a term for an epimerase that changes optical activity. This enzyme was shown experimentally to interconvert alpha and beta stereoisomers of the pyranose form of L-rhamnose. The crystal structure of this small (104 amino acid) protein shows a locally asymmetric dimer with active site residues of His, Tyr, and Trp. [Energy metabolism, Sugars].	3.46584e-64
NC_008253.1\|WP_000027720.1\|4283583_4284513_-\|formate-dehydrogenase-accessory-protein-FdhE	gnl\|CDD\|179595	PRK03564, PRK03564, formate dehydrogenase accessory protein FdhE; Provisional.	0
NC_008253.1\|WP_077634631.1\|4286056_4289107_-\|formate-dehydrogenase-N-subunit-alpha	gnl\|CDD\|273689	TIGR01553, Formate_dehydrogenase_major_subunit, formate dehydrogenase-N alpha subunit. This model describes a subset of formate dehydrogenase alpha chains found mainly in proteobacteria but also in Aquifex. The alpha chain contains domains for molybdopterin dinucleotide binding and molybdopterin oxidoreductase (pfam01568 and pfam00384, respectively). The holo-enzyme also contains beta and gamma subunits of 32 and 20 kDa. The enzyme catalyzes the oxidation of formate (produced from pyruvate during anaerobic growth) to carbon dioxide with the concomitant release of two electrons and two protons. The electrons are utilized mainly in the nitrate respiration by nitrate reductase. In E. coli and Salmonella, there are two forms of the formate dehydrogenase, one induced by nitrate which is strictly anaerobic (fdn), and one incuced during the transition from aerobic to anaerobic growth (fdo). This subunit is one of only three proteins in E. coli which contain selenocysteine. This model is well-defined, with a large, unpopulated trusted/noise gap. [Energy metabolism, Anaerobic, Energy metabolism, Electron transport].	0
NC_008253.1\|WP_001298417.1\|4300112_4300733_+\|superoxide-dismutase-[Mn]	gnl\|CDD\|182843	PRK10925, PRK10925, superoxide dismutase [Mn].	1.57037e-152
NC_008253.1\|WP_001166063.1\|4300992_4301976_+\|2-keto-3-deoxygluconate-transporter	gnl\|CDD\|273271	TIGR00793, 2-keto-3-deoxygluconate_permease, 2-keto-3-deoxygluconate transporter. This family includes the characterized 2-Keto-3-Deoxygluconate transporters from Bacillus subtilis and Erwinia chrysanthemi. There are homologs of this protein found in both gram-positive and gram-negative bacteria. [Transport and binding proteins, Carbohydrates, organic alcohols, and acids].	7.59733e-165

>NC_008253.1|WP_001179744.1|4293025_4293850_-|rhamnulose-1-phosphate-aldolase
MQNITQSWFVQGMIKATTDAWLKGWDERNGGNLTLRLDDADIAPYHDNFHQQPRYIPLSQPMPLLANTPFIVTGSGKFFRNVQLDPAANLGIVKVDSDGAGYHILWGLTNEAVPTSELPAHFLSHCERIKATNGKDRVIMHCHATNLIALTYVLENDTAVFTRQLWEGSTECLVVFPDGVGILPWMVPGTDEIGQATAQEMQKHSLVLWPFHGVFGSGPTLDETFGLIDTAEKSAQILVKVYSMGGMKQTISREELIALGQRFGVTPLASALAL
>NC_008253.1|WP_000619492.1|4292701_4293016_-|L-rhamnose-mutarotase
MIRKAFVMQVNPDAHEEYQRRHNPIWPELEAVLKSHGAHNYAIYLDKAHNLLFATVEIESEERWNAVASTDVCQRWWKYMTDVMPANADNSPVSSELQEVFYLP
>NC_008253.1|WP_000749943.1|4291266_4292661_+|carbohydrate-porin
MKKSTLSLAIGLLLACSTGMAKTQHLTLEQRMALLEERLEAAEMRAAKAESQVKQLQTQQAAEIREIKAAQGNTPVNGQATAESAKKNSTSPNLLLSGYGDLKIYGDVEFNMDAESNHGLLAMTNADVNSDPTNEQWNLNGRILLGFDGMRKLDNGYFAGFSAQPLGDMHGSVNIDDAVFFFGKENDWKVKVGRFEAYDMFPLNQDTFVEHSGNTANDLYDDGSGYIYMMKEGRGRSNAGGNFLVSKQLDNWYFELNTLLEDGTSLYNDGNYHGRDMEQQKNVAYLRPVIAWSPTEEFTVSAAMEANVVNNAYGYTDSKGNFVDQSDRTGYGMSMTWNGLKTDPENGIVVNLNTAYLDANNEKDFTAGINALWKRFELGYIYAHNKIDEFSGVVCDNDCWIDDEGTYNIHTIHASYQFANVMDMENFNIYLGTYYSILDSDGDKIHGDDSDDRYGARVRFKYFF
>NC_008253.1|WP_178278646.1|4290162_4290846_+|DUF3829-domain-containing-protein
MAGLIHFVNFIILFINKTRVVALTPALQPIDGVAVSYIDAAVALGNTINEMDKYYIQENYKDDAFAKGKTLHQTFLKNLEAFEPVAESYHAAIQEINDKRQLTELKNIEEREGKTFHYYSLAVMISAKQINNLISQDKFDAEAAMKKVSELETLVAQVKEADKSGMNFSFINSAGQYQLEAKKYVRRIRDKVPYSDWDKEQLQDANSSWMAEDSFPESIMRVQRNGR
>NC_008253.1|WP_000753582.1|4289300_4290134_+|formate-dehydrogenase-accessory-sulfurtransferase-FdhD
MKKTQQKEIENVTNITGVRQIELWRHDDLQHPRLDEVAEEVPVALVYNGISHVVMMASPKDLEYFALGFSLSEGIIESPRDIFGMDVVPSCNGLEVQIELSSRRFMGLKERRRALAGRTGCGVCGVEQLNDIGKPVQPLPFTQTFDLNKLDDALRHLNDFQPVGQLTGCTHAAAWMLPSGELVGGHEDVGRHVALDKLLGRRSQEGESWQQGAVLVSSRASYEMVQKSAMCGVEILFAVSAATTLAVEVAERCNLTLVGFCKPGRATVYTHPQRLSN
>NC_008253.1|WP_077634631.1|4286056_4289107_-|formate-dehydrogenase-N-subunit-alpha
MQVSRRQFFKICAGGMAGTTAAALGFAPSVALAETRQYKLLRTRETRNTCTYCSVGCGLLMYSLGDGAKNAKASIFHIEGDPDHPVNRGALCPKGAGLVDFIHSESRLKFPEYRAPGSDKWQQISWEEAFDRIAKLMKEDRDANYIAQNAEGVTVNRWLSTGMLCASASSNETGYLTQKFSRALGMLAVDNQARVUHGPTVASLAPTFGRGAMTNHWVDIKNANLVVVMGGNAAEAHPVGFRWAMEAKIHNGAKLIVIDPRFTRTAAVADYYAPIRSGTDIAFLSGVLLYLLNNEKFNREYTEAYTNASLIVREDYGFEDGLFTGYDAEKRKYDKSSWTYELDENGFAKRDTTLQHPRCVWNLLKQHVSRYTPDVVENICGTPKDAFLKVCEYIAETSAHDKTASFLYALGWTQHSIGAQNIRTMAMIQLLLGNMGMAGGGVNALRGHSNIQGLTDLGLLSQSLPGYMTLPSEKQTDLQTYLTANTPKPLLEGQVNYWGNYPKFFVSMMKAFFGDKATAENSWGFDWLPKWDKGYDVLQYFEMMKEGKVNGYICQGFNPVASFPNKNKVIGCLSKLKFLVTIDPLNTETSNFWQNHGELNEVDSSKIQTEVFRLPSTCFAEENGSIVNSGRWLQWHWKGADAPGIALTDGEILSGIFLRLRKMYAEQGGANPDQVLNMTWNYAIPHEPSSEEVAMESNGKALADITDPATGAVIVKKGQQLSSFAQLRDDGTTSCGCWIFAGSWTPEGNQMARRDNADPSGLGNTLGWAWAWPLNRRILYNRASADPQGNPWDPKRQLLKWDGTKWTGWDIPDYSAAPPGSGVGPFIMQQEGMGRLFALDKMAEGPFPEHYEPFETPLGTNPLHPNVISNPAARIFKDDAEALGKADKFPYVGTTYRLTEHFHYWTKHALLNAILQPEQFVEIGESLANKLGIAQGDTVKVSSNRGYIKAKAVVTKRIRTLKANGKDIDTIGIPIHWGYEGVAKKGFIANTLTPFVGDANTQTPEFKSFLVNVEKV
>NC_008253.1|WP_000331377.1|4285141_4286044_-|formate-dehydrogenase-O-subunit-beta
MAYQSQDIIRRSATNGLTPAPQARDFQEEVAKLIDVTTCIGCKACQVACSEWNDIRDTVGNNIGVYDNPNDLSAKSWTVMRFSEVEQNDKLEWLIRKDGCMHCSDPGCLKACPAEGAIIQYANGIVDFQSEQCIGCGYCIAGCPFDIPRLNPEDNRVYKCTLCVDRVVVGQEPACVKTCPTGAIHFGTKESMKTLASERVAELKTRGYDNAGLYDPAGVGGTHVMYVLHHADKPNLYHGLPENPEISETVKFWKGIWKPLAAVGFAATFAASIFHYVGVGPNRADEEENNLHEEKDEERK
>NC_008253.1|WP_000829013.1|4284509_4285145_-|formate-dehydrogenase-cytochrome-b556-subunit
MKRRDTIVRYTAPERINHWITAFCFILAAVSGLGFLFPSFNWLMQIMGTPQLARILHPFVGVVMFASFIIMFFRYWHHNLINRDDIFWAKNIRKIVVNEEVGDTGRYNFGQKCVFWAAIIFLVLLLVSGVIIWRPYFAPAFSIPVIRFALMLHSFAAVALIVVIMVHIYAALWVKGTITAMVEGWVTSAWAKKHHPRWYREVRKTTEKKAE
>NC_008253.1|WP_000027720.1|4283583_4284513_-|formate-dehydrogenase-accessory-protein-FdhE
MSIRIIPQDELGSSEKRTADMIPPLLFPRLKNLYNRRAERLRELAENNPLGDYLRFAALIAHAQEVVLYDHPLEMDLTTRIKEASAQGKPPLDIHVLPRDKHWQKLLMALIAELKPEMSGPALAVIENLEKASTQELEDMASALFASDFSSVSSDKAPFIWAALSLYWAQMANLIPGKARAEYGEQRQYCPVCGSMPVSSMVQIGTTQGLRYLHCNLCETEWHVVRVKCSNCEQSGKLHYWSLDDEQAAIKAESCDDCGTYLKILYQEKEPKVEAVADDLASLVLDARMEQEGYARSSINPFLFPGEGE
>NC_008253.1|WP_001298592.1|4283150_4283369_+|CopG-family-transcriptional-regulator
MAMNTVFLHLSEEAIKRLNKLRGWRKVSRSAILREAVEQYLERQQFPVRKAKGGRQRGETVVVDDQCKEHKE
>NC_008253.1|WP_001298699.1|4294024_4295284_-|L-rhamnose-isomerase
MTTQLEQAWELAKQRFAAVGIDVEEALRQLDRLPVSMHCWQGDDVSGFENPEGSLTGGIQATGNYPGKARNASELRADLEQAMRLIPGPKRLNLHAIYLESDTPVSRDQIKPEHFKNWVEWAKANQLGLDFNPSCFSHPLSADGFTLSHADDRIRQFWIDHCKASRRVSAYFGEQLGTPSVMNIWIPDGMKDITVDRLAPRQRLLAALDEVISEKLNPAHHIDAVESKLFGIGAESYTVGSNEFYLGYATSRQTALCLDAGHFHPTEVISDKISAAMLYVPQLLLHVSRPVRWDSDHVVLLDDETQAIASEIVRHDLFDRVHIGLDFFDASINRIAAWVIGTRNMKKALLRALLEPTAELRKLEAAGDYTARLALLEEQKSLPWQAVWEMYCQRHDTPAGSEWLENVRTYEKEILSRRG
>NC_008253.1|WP_000144094.1|4295280_4296750_-|rhamnulokinase
MTFRNCVAVDLGASSGRVMLARYERECRSLTLREIHRFNNGLHSQNGYVTWNVDRLESAIRLGLNKVCEEGIRIDSIGIDTWGVDFVLLDQQGQRVGLPVAYRDSRTNGLMAQAQQQLGKRDIYQRSGIQFLPFNTIYQLRALTEQQPELIPHIAHALLIPDYFSYRLTGKMNWEYTNATTTQLVNINSDDWDESLLAWSGANKAWFGRPTHPGNVIGHWICPQGNEIPVVAVASHDTASAVIASPLNGSRAAYLSSGTWSLMGFESQTPFTNDTALAANITNEGGAEGRYRVLKNIMGLWLLQRVLQERQINDLPALIAATQALPACRFIINPNDDRFINPDEMCSEIQAACRETAQPIPESDAELARCIFDSLALLYADVLHELAQLRGEDFSQLHIVGGGCQNALLNQLCADACGIRVIAGPVEASTLGNIGIQLMTLDELNNVDDFRQVVSTTANLTTFTPNPDSEIAHYVAQIHSTRQTKELCA
>NC_008253.1|WP_000217156.1|4297037_4297874_+|HTH-type-transcriptional-activator-RhaS
MTVLHSVDFFPSGNASVAIEPRLPQADFPEHHHDFHEIVIVEHGTGIHVFNGQPYTITGGTVCFVRDHDRHLYEHTDNLCLTNVLYRSPDRFQFLAGLNQLLPQEQDGQYPSHWRVNHSVLQQVRQLVAQMEQQEGENDLPSTASREILFMQLLLLLRKSSLQENLENSASRLNLLLAWLEDHFADEVNWDAVADQFSLSLRTLHRQLKQQTGLTPQRYLNRLRLMKARHLLRHSEASVTDIAYRCGFSDSNHFSTLFRREFNWSPRDIRQGRDGFLQ
>NC_008253.1|WP_001296618.1|4297857_4298796_+|HTH-type-transcriptional-activator-RhaR
MVFCNNANLLNVFVRHIANNQLRSLAEVATVAHQLKLLKDDFFASDQQAVAVADRYPQDVFAEHTHDFCELVIVWRGNGLHVLNDRPYRITRGDLFYIHADDKHSYASVNDLVLQNIIYCPERLKLNLDWQGAIPGFSASAGQPHWRLGSVGMAQARQVIGQLEHESSQHVSFANEMAELLFGQLVMLLNRHRYTSDSLPPTSSETLLDKLITRLAASLKSPFALDKFCDEASCSERVLRQQFRQQTGMTINQYLRQVRVCHAQYLLQHSRLLISDISTECGFEDSNYFSVVFTRETGMTPSQWRHLNSQKD
>NC_008253.1|WP_000063507.1|4298792_4299827_-|L-rhamnose/proton-symporter-RhaT
MSNAITMGIFWHLIGAASAACFYAPFKKVKKWSWETMWSVGGIVSWIILPWAISALLLPNFWAYYSSFSLSTLLPVFLFGAMWGIGNINYGLTMRYLGMSMGIGIAIGITLIVGTLMTPIINGNFDVLINTEGGRMTLLGVLVALIGVGIVTRAGQLKERKMGIKAEEFNLKKGLVLAVMCGIFSAGMSFAMNAAKPMHEAAAALGVDPLYVALPSYVVIMGGGAIINLGFCFIRLAKVKDLSLKADFSLAKPLIIHNVLLSALGGLMWYLQFFFYAWGHARIPAQYDYISWMLHMSFYVLCGGIVGLVLKEWNNAGRRPVTVLSLGCVVIIVAANIVGIGMAN
>NC_008253.1|WP_001298417.1|4300112_4300733_+|superoxide-dismutase-[Mn]
MSYTLPSLPYAYDALEPHFDKQTMEIHHTKHHQTYVNNANAALENLPEFANLPVEELITKLDQLPADKKTVLRNNAGGHANHSLFWKGLKKGTTLQGDLKAAIERDFGSVDNFKAEFEKAAASRFGSGWAWLVQKGDKLAVVSTANQDSPLMGEAISGASGFPILGLDVWEHAYYLKFQNRRPDYIKEFWNVVNWDEAAARFAAKK
>NC_008253.1|WP_001166063.1|4300992_4301976_+|2-keto-3-deoxygluconate-transporter
MQIKRSIEKIPGGMMLVPLFLGALCHTFSPGAGKYFGSFTNGMITGTVPILAVWFFCMGASIKLSATGTVLRKSGTLVVTKIAVAWVVAAIASRIIPEHGVEVGFFAGLSTLALVAAMDMTNGGLYASIMQQYGTKEEAGAFVLMSLESGPLMTMIILGTAGIASFEPHVFVGAVLPFLVGFALGNLDPELREFFSKAVQTLIPFFAFALGNTIDLTVIAQTGLLGILLGVAVIIVTGIPLIIADKLIGGGDGTAGIAASSSAGAAVATPVLIAEMVPAFKPMAPAATSLVATAVIVTSILVPILTSIWSRKVKARAAKIEILGTVK
>NC_008253.1|WP_001270236.1|4302124_4302799_+|6-N-hydroxylaminopurine-resistance-protein
MRYPVDVYTGKIQAYPEGKPSAIAKIQVDGELMLTDLGLEGDEQAEKKIHGGPDRALCHYPREHYLYWAREFPEQAELFVAPAFGENLSTDGLTESNVYIGDIFRWGEALIQVSQPRSPCYKLNYHFDISDIAQLMQNTGKVGWLYSVIAPGLVSADAPLELVSRVSDMTVQEAAAIAWHMPFDDDQYHRLLSAAGLSKSWTRTMQKRRLSGKIEDFSRRLWGK
>NC_008253.1|WP_000580417.1|4302970_4304344_-|envelope-stress-sensor-histidine-kinase-CpxA
MIGSLTARIFAIFWLTLALVLMLVLMLPKLDSRQMTELLDSEQRQGLMIEQHVEAELANDPPNDLMWWRRLFRAIDKWAPPGQRLLLVTTEGRVIGAERSEMQIIRNFIGQADNADHPQKKKYGRVELVGPFSVRDGEDNYQLYLIRPASSSQSDFINLLFDRPLLLLIVTMLVSTPLLLWLAWSLAKPARKLKNAADEVAQGNLRQHPELEAGPQEFLAAGASFNQMVTALERMMTSQQRLLSDISHELRTPLTRLQLGTALLRRRSGESKELERIETEAQRLDSMINDLLVMSRNQQKNALVSETIKANQLWSEVLDNAAFEAEQMGKSLTVNFPPGPWPLYGNPNALESALENIVRNALRYSHTKIEVGFAVDKDGITITVDDDGPGVSPEDREQIFRPFYRTDEARDRESGGTGLGLAIVETAIQQHRGWVKAEDSPLGGLRLVIWLPLYKRS
>NC_008253.1|WP_001033719.1|4304340_4305039_-|envelope-stress-response-regulator-transcription-factor-CpxR
MNKILLVDDDRELTSLLKELLEMEGFNVIVAHDGEQALDLLDDSIDLLLLDVMMPKKNGIDTLKALRQTHQTPVIMLTARGSELDRVLGLELGADDYLPKPFNDRELVARIRAILRRSHWSEQQQNNDNGSPTLEVDALSLNPGRQEASFDGQTLELTGTEFTLLYLLAQHLGQVVSREHLSQEVLGKRLTPFDRAIDMHISNLRRKLPDRKDGHPWFKTLRGRGYLMVSAS

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Crispr_ID: NC_008253_7

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_008253_7

4723019-4723158

Orphan

Consensus_repeat	Method
TGTGTAGGTCGGATAAGGCGTTCACGCCGCATCCGACAATAACA	CRISPRCasFinder

1 spacers

The CRISPR arrays of NC_008253_7

>merge|NC_008253|7|4723019-4723158|CRISPRCasFinder
TGTGTAGGTCGGATAAGGCGTTCACGCCGCATCCGACAATAACAGCCTTGCCTGATGCGACGCTGTCGCGTCTCATCAGGCCTACGAGTTCAGTGCTGTGTAGGTCGGATAAGGCGTTCACGCCGCATCCGACAATAACA

>NC_008253|7|6|4723019-4723158|CRISPRCasFinder
TGTGTAGGTCGGATAAGGCGTTCACGCCGCATCCGACAATAACA	GCCTTGCCTGATGCGACGCTGTCGCGTCTCATCAGGCCTACGAGTTCAGTGC
TGTGTAGGTCGGATAAGGCGTTCACGCCGCATCCGACAATAACA

Protein	Signature genes	Signature genes Name	Protein_function
NC_008253.1\|WP_001298035.1\|4717688_4718192_-\|GNAT-family-N-acetyltransferase	unknown	unknown	gnl\|CDD\|366181
NC_008253.1\|WP_001294541.1\|4727295_4728798_-\|DUF853-domain-containing-protein	unknown	unknown	gnl\|CDD\|283518
NC_008253.1\|WP_001000688.1\|4718384_4719572_+\|DUF898-family-protein	unknown	unknown	gnl\|CDD\|226719
NC_008253.1\|WP_011579310.1\|4711587_4712568_-\|ornithine-carbamoyltransferase	unknown	unknown	gnl\|CDD\|179366
NC_008253.1\|WP_000584114.1\|4724952_4726053_+\|LPS-export-ABC-transporter-permease-LptF	unknown	unknown	gnl\|CDD\|185075
NC_008253.1\|WP_000397144.1\|4723174_4724686_-\|leucyl-aminopeptidase	unknown	unknown	gnl\|CDD\|234863
NC_008253.1\|WP_001298046.1\|4710104_4711508_-\|YfcC-family-protein	unknown	unknown	gnl\|CDD\|224207
NC_008253.1\|WP_001298043.1\|4713533_4714754_-\|arginine-deiminase	unknown	unknown	gnl\|CDD\|234949
NC_008253.1\|WP_011579311.1\|4728875_4729874_-\|DNA-binding-transcriptional-regulator-IdnR	unknown	unknown	gnl\|CDD\|380489
NC_008253.1\|WP_000416385.1\|4719618_4722474_-\|valine--tRNA-ligase	unknown	unknown	gnl\|CDD\|235582
NC_008253.1\|WP_001219008.1\|4735417_4736680_+\|integrase-arm-type-DNA-binding-domain-containing-protein	unknown	unknown	gnl\|CDD\|170049
NC_008253.1\|WP_000998702.1\|4731324_4732089_-\|gluconate-5-dehydrogenase	unknown	unknown	gnl\|CDD\|181225
NC_008253.1\|WP_000002956.1\|4717095_4717512_+\|ribonuclease-E-inhibitor-RraB	unknown	unknown	gnl\|CDD\|236876
NC_008253.1\|WP_000635215.1\|4715431_4715884_+\|YhcH/YjgK/YiaL-family-protein	unknown	unknown	gnl\|CDD\|225345
NC_008253.1\|WP_001197423.1\|4732112_4733144_-\|L-idonate-5-dehydrogenase	unknown	unknown	gnl\|CDD\|182130
NC_008253.1\|WP_001128336.1\|4729940_4731260_-\|gnt-II-system-L-idonate-transporter	unknown	unknown	gnl\|CDD\|129873
NC_008253.1\|WP_000786399.1\|4722473_4722917_-\|DNA-polymerase-III-subunit-chi	unknown	unknown	gnl\|CDD\|235581
NC_008253.1\|WP_001295681.1\|4726052_4727135_+\|LPS-export-ABC-transporter-permease-LptG	unknown	unknown	gnl\|CDD\|237900
NC_008253.1\|WP_000428626.1\|4712578_4713523_-\|carbamate-kinase	unknown	unknown	gnl\|CDD\|183466
NC_008253.1\|WP_001298045.1\|4733931_4734951_-\|NADPH-dependent-aldehyde-reductase-Ahr	unknown	unknown	gnl\|CDD\|176186

Protein	Function_ID	Function_description	E-value
NC_008253.1\|WP_001298035.1\|4717688_4718192_-\|GNAT-family-N-acetyltransferase	gnl\|CDD\|366181	pfam00583, Acetyltransf_1, Acetyltransferase (GNAT) family. This family contains proteins with N-acetyltransferase functions such as Elp3-related proteins.	1.51706e-18
NC_008253.1\|WP_001294541.1\|4727295_4728798_-\|DUF853-domain-containing-protein	gnl\|CDD\|283518	pfam05872, DUF853, Bacterial protein of unknown function (DUF853). This family consists of several bacterial proteins of unknown function. BMEI1370 is thought to be an ATPase.	0
NC_008253.1\|WP_001000688.1\|4718384_4719572_+\|DUF898-family-protein	gnl\|CDD\|226719	COG4269, COG4269, Predicted membrane protein [Function unknown].	6.82189e-106
NC_008253.1\|WP_011579310.1\|4711587_4712568_-\|ornithine-carbamoyltransferase	gnl\|CDD\|179366	PRK02102, PRK02102, ornithine carbamoyltransferase; Validated.	0
NC_008253.1\|WP_000584114.1\|4724952_4726053_+\|LPS-export-ABC-transporter-permease-LptF	gnl\|CDD\|185075	PRK15120, PRK15120, lipopolysaccharide ABC transporter permease LptF; Provisional.	0
NC_008253.1\|WP_000397144.1\|4723174_4724686_-\|leucyl-aminopeptidase	gnl\|CDD\|234863	PRK00913, PRK00913, multifunctional aminopeptidase A; Provisional.	0
NC_008253.1\|WP_001298046.1\|4710104_4711508_-\|YfcC-family-protein	gnl\|CDD\|224207	COG1288, COG1288, Predicted membrane protein [Function unknown].	0
NC_008253.1\|WP_001298043.1\|4713533_4714754_-\|arginine-deiminase	gnl\|CDD\|234949	PRK01388, PRK01388, arginine deiminase; Provisional.	0
NC_008253.1\|WP_011579311.1\|4728875_4729874_-\|DNA-binding-transcriptional-regulator-IdnR	gnl\|CDD\|380489	cd01575, PBP1_GntR, ligand-binding domain of DNA transcription repressor GntR specific for gluconate, a member of the LacI-GalR family of bacterial transcription regulators. This group represents the ligand-binding domain of DNA transcription repressor GntR specific for gluconate, a member of the LacI-GalR family of bacterial transcription regulators. The ligand-binding domain of GntR is structurally homologous to the periplasmic sugar-binding domain of ABC-type transporters and both domains contain the type 1 periplasmic binding protein-like fold. The LacI-GalR family repressors are composed of two functional domains: an N-terminal HTH (helix-turn-helix) domain, which is responsible for the DNA-binding specificity, and a C-terminal ligand-binding domain, which is homologous to the type 1 periplasmic binding proteins. As also observed in the periplasmic binding proteins, the C-terminal domain of the bacterial transcription repressor undergoes a conformational change upon ligand binding, which in turn changes the DNA binding affinity of the repressor.	2.90371e-107
NC_008253.1\|WP_000416385.1\|4719618_4722474_-\|valine--tRNA-ligase	gnl\|CDD\|235582	PRK05729, valS, valyl-tRNA synthetase; Reviewed.	0
NC_008253.1\|WP_001219008.1\|4735417_4736680_+\|integrase-arm-type-DNA-binding-domain-containing-protein	gnl\|CDD\|170049	PRK09692, PRK09692, integrase; Provisional.	1.50962e-80
NC_008253.1\|WP_000998702.1\|4731324_4732089_-\|gluconate-5-dehydrogenase	gnl\|CDD\|181225	PRK08085, PRK08085, gluconate 5-dehydrogenase; Provisional.	0
NC_008253.1\|WP_000002956.1\|4717095_4717512_+\|ribonuclease-E-inhibitor-RraB	gnl\|CDD\|236876	PRK11191, PRK11191, ribonuclease E inhibitor RraB.	1.76383e-68
NC_008253.1\|WP_000635215.1\|4715431_4715884_+\|YhcH/YjgK/YiaL-family-protein	gnl\|CDD\|225345	COG2731, EbgC, Beta-galactosidase, beta subunit [Carbohydrate transport and metabolism].	1.2775e-64
NC_008253.1\|WP_001197423.1\|4732112_4733144_-\|L-idonate-5-dehydrogenase	gnl\|CDD\|182130	PRK09880, PRK09880, L-idonate 5-dehydrogenase; Provisional.	0
NC_008253.1\|WP_001128336.1\|4729940_4731260_-\|gnt-II-system-L-idonate-transporter	gnl\|CDD\|129873	TIGR00791, Gluconate_permease, gluconate transporter. This family includes known gluconate transporters of E. coli and Bacillus species as well as an idonate transporter from E. coli. [Transport and binding proteins, Carbohydrates, organic alcohols, and acids].	0
NC_008253.1\|WP_000786399.1\|4722473_4722917_-\|DNA-polymerase-III-subunit-chi	gnl\|CDD\|235581	PRK05728, PRK05728, DNA polymerase III subunit chi; Validated.	5.53743e-66
NC_008253.1\|WP_001295681.1\|4726052_4727135_+\|LPS-export-ABC-transporter-permease-LptG	gnl\|CDD\|237900	PRK15071, PRK15071, lipopolysaccharide ABC transporter permease; Provisional.	0
NC_008253.1\|WP_000428626.1\|4712578_4713523_-\|carbamate-kinase	gnl\|CDD\|183466	PRK12354, PRK12354, carbamate kinase; Reviewed.	0
NC_008253.1\|WP_001298045.1\|4733931_4734951_-\|NADPH-dependent-aldehyde-reductase-Ahr	gnl\|CDD\|176186	cd05283, CAD1, Cinnamyl alcohol dehydrogenases (CAD). Cinnamyl alcohol dehydrogenases (CAD), members of the medium chain dehydrogenase/reductase family, reduce cinnamaldehydes to cinnamyl alcohols in the last step of monolignal metabolism in plant cells walls. CAD binds 2 zinc ions and is NADPH- dependent. CAD family members are also found in non-plant species, e.g. in yeast where they have an aldehyde reductase activity. The medium chain dehydrogenases/reductase (MDR)/zinc-dependent alcohol dehydrogenase-like family, which contains the zinc-dependent alcohol dehydrogenase (ADH-Zn) and related proteins, is a diverse group of proteins related to the first identified member, class I mammalian ADH. MDRs display a broad range of activities and are distinguished from the smaller short chain dehydrogenases (~ 250 amino acids vs. the ~ 350 amino acids of the MDR). The MDR proteins have 2 domains: a C-terminal NAD(P) binding-Rossmann fold domain of a beta-alpha form and an N-terminal catalytic domain with distant homology to GroES. The MDR group contains a host of activities, including the founding alcohol dehydrogenase (ADH), quinone reductase, sorbitol dehydrogenase, formaldehyde dehydrogenase, butanediol DH, ketose reductase, cinnamyl reductase, and numerous others. The zinc-dependent alcohol dehydrogenases (ADHs) catalyze the NAD(P)(H)-dependent interconversion of alcohols to aldehydes or ketones. Active site zinc has a catalytic role, while structural zinc aids in stability. ADH-like proteins typically form dimers (typically higher plants, mammals) or tetramers (yeast, bacteria), and generally have 2 tightly bound zinc atoms per subunit. The active site zinc is coordinated by a histidine, two cysteines, and a water molecule. The second zinc seems to play a structural role, affects subunit interactions, and is typically coordinated by 4 cysteines.	5.98969e-169

>NC_008253.1|WP_000786399.1|4722473_4722917_-|DNA-polymerase-III-subunit-chi
MKNATFYLLDNDTTVDGLSAVEQLVCEIAAERWRSGKRVLIACEDEKQAYRLDEALWARPAESFVPHNLAGEGPRGGAPVEIAWPQKRSSSPRDILISLRTSFADFATAFTEVVDFVPYEDSLKQLARERYKAYRVAGFNLNTATWK
>NC_008253.1|WP_000416385.1|4719618_4722474_-|valine--tRNA-ligase
MEKTYNPQDIEQPLYEHWEKQGYFKPNGDESQESFCIMIPPPNVTGSLHMGHAFQQTIMDTMIRYQRMQGKNTLWQVGTDHAGIATQMVVERKIAAEEGKTRHDYGREAFIDKIWEWKAESGGTITRQMRRLGNSVDWERERFTMDEGLSNAVKEVFVRLYKEDLIYRGKRLVNWDPKLRTAISDLEVENRESKGSMWHIRYPLADGAKTADGKDYLVVATTRPETLLGDTGVAVNPEDPRYKDLIGKYVILPLVNRRIPIVGDEHADMEKGTGCVKITPAHDFNDYEVGKRHALPMINILTFDGDIRESAQVFDTKGNESDVYSSEIPAEFQKLERFAARKAVVAAVDALGLLEEIKPHDLTVPYGDRGGVVIEPMLTDQWYVRADVLAKPAVEAVENGDIQFVPKQYENMYFSWMRDIQDWCISRQLWWGHRIPAWYDEAGNVYVGRNEDEVRKENNLGADVALRQDEDVLDTWFSSALWTFSTLGWPENTDALRQFHPTSVMVSGFDIIFFWIARMIMMTMHFIKDENGKPQVPFHTVYMTGLIRDDEGQKMSKSKGNVIDPLDMVDGISLPELLEKRTGNMMQPQLADKIRKRTEKQFPNGIEPHGTDALRFTLAALASTGRDINWDMKRLEGYRNFCNKLWNASRFVLMNTEGQDCGFNGGEMTLSLADRWILAEFNQTIKAYREALDSFRFDIAAGILYEFTWNQFCDWYLELTKPVMNGGTEAELRGTRHTLVTVLEGLLRLAHPIIPFITETIWQRVKVLCGITADTIMLQPFPQYDASQVDEAALADTEWLKQAIVAVRNIRAEMNIAPGKPLELLLRGCSADAERRVNENRGFLQTLARLESITVLPADDKGPVSVTKIVDGAELLIPMAGLINKEDELARLAKEVAKIEGEISRIENKLANEGFVARAPEAVIAKEREKLEGYAEAKAKLIEQQAVIAAL
>NC_008253.1|WP_001000688.1|4718384_4719572_+|DUF898-family-protein
MNDVNIGKDNSRHSFVFTGKGGEYFLICLVSFLLTIITLGIYGPWALIKCRRYIYQHVTLKGQPFSYKGTGGAIFVSMLLIVVVYLLSISCFAGQHFALGLFLFALLICGIPCMAVKSLQYQANMTSLNDIRFGFNCSMMRAWWVMLGLPVLLALVFWFALYLIAQVTTSIGGLFFNLVALSLLSAIGLGVVHGITYSKWMPLLGNNATFGIHKFSIQVNVKECIKGCMLAILTMVPFIIVIGIMIAPVFQQLMMMTMLGRSDAGSEFVLQYYPQIMASYFLYFVAILVFASYLYVTLRNLFLNNLTLANGTIRFHSSVTAIGMLLRMLAVLMGSSITCGLAYPWLKMWMVSWIANNTHVQGDLDSLELTNDDKPQDSGSLMWISRGIMPYVPFI
>NC_008253.1|WP_001298035.1|4717688_4718192_-|GNAT-family-N-acetyltransferase
MNVVASPALRLRKLTVADNPAIAHVIRQVSAEYGLTADKGYTVADPNLDELYQVYSQPGHAYWVVEYEGEVVGGGGIAPLTGSESDICELQKMYFLPAIRGKGLAKKLALMAMEQAREMGFKRCYLETTAFLKEAIALYEHLGFEHIDYALGCTGHVDCEVRMLRKL
>NC_008253.1|WP_000002956.1|4717095_4717512_+|ribonuclease-E-inhibitor-RraB
MANPEQLEEQREETRLIIEELLEDGSDPDALYTIEHHLSADDLETLEKAAVEAFKLGYEVTDPEELEVEDGDIVICCDILSECALNADMIDAQVEQLMTLAEKFDVEYDGWGTYFEDPNGDDGDDEDFVDEDDDGIRH
>NC_008253.1|WP_000635215.1|4715431_4715884_+|YhcH/YjgK/YiaL-family-protein
MIVGNIHHLQSWLPEELREAIEYIKSHVSDETAKGKHAIDGDRLFYLISEDTTEPGELRRAEYHARYLDIQIVLKGQEGMTFSTQPAGVPETDWLADKDIAFIGQGIDEKTVILNEGDFVVFYPGEVHKPLCAVGAPAQVRKAVVKLLKA
>NC_008253.1|WP_001298043.1|4713533_4714754_-|arginine-deiminase
MEKHYVGSEIGQLCSVMLHRPNLSLKRLTPSNCQELLFDDVLSVERAGEEHDIFANTLRQQGIEVLLLTDLLTQTLDIPEAKSWLLETQISDYRLGPTFATDVRTWLAEMSHRDLARHLSGGLTYSEIPASIKNMVVDTHDINDFIMKPLPNHLFTRDTSCWIYNGVSINPMAKPARQRETNNLRAIYRWHPQFAGGEFIKYFGDENINYDHATLEGGDVLVIGRGAVLIGMSERTTPQGVEFLAQALFKHRQAERVIAVELPKHRYCMHLDTVMTHIDIDTFSVYPEVVRPDVNCWTLTPDGHGGLKRTQESTLLHAIEKALGIDQVRLITTGGDAFEAEREQWNDANNVLTLRPGVVVGYERNIWTNEKYDKAGITVLPIPGDELGRGRGGARCMSCPLHRDGI
>NC_008253.1|WP_000428626.1|4712578_4713523_-|carbamate-kinase
MENKPTLVIALGGNALLKRGEPLEAEIQRKNIDLAAKTIAQLTQHWRVVLVHGNGPQVGLLALQNSAYAHVAPYPLDILGAESQGMIGYMLQQALKNQLPQREISVLLTQVEVDANDPAFSNPTKYIGPIYDHAQTQVLQAEKGWVFKADGHSFRRVVPSPQPKRIVERDAIQTLIAHDHLVICNGAGGVPVVEKADGYHGIEAVIDKDLSAALLASQIHADALLILTDADAVYLDWGKPTQRPLAQVTPELLNEMQFDAGSMGPKVTACAKFVSQCRGIAGIGSLADGPEILAGDKGTLIRLDTPITTLDPFL
>NC_008253.1|WP_011579310.1|4711587_4712568_-|ornithine-carbamoyltransferase
MATSLKNRNFLKLLDYTPAEIQYLIDLAINLKAAKKSGNEKQTLVGKNIALIFEKSSTRTRCAFEVAAFDQGAQVTYIGPSGSQIGHKESMKDTARVLGRMYDGIEYRGYGQNIVEELGEFAGVPVWNGLTNEFHPTQILADLMTMLEHAPGKTLPELSFAYLGDARNNMGNSLMVGAAKMGMDIRLVAPKSFWPDEALVTQCREIASVTGARITLTEDVEEGVYDVDFLYTDVWVSMGEPKEAWAERVSLMAPYQINQQVITATRNPEVKFMHCLPAFHNEHTTVGREIEMAYGSKDWKLLKRFLNRPTLLFSMKQKTGCTPLKR
>NC_008253.1|WP_001298046.1|4710104_4711508_-|YfcC-family-protein
MGKFKFPTAYTILFVLIALVAAMTWIVPAGKYQMVTNAALGKEVPVAGTYAPVEAQPQGITAVLLAPIDGLYNHQTYTAGAIDVALFVLIIGGFLGVVNKTGAIDAGIERVTTRLNGREEWMIPILMALFAAGGTIYGMAEESLPFYTLLVPVMMAARFDPLVAAATVLLGSGIGTLGSTINPFATVIAANAAGIPFTQGILLRVILLLVGYVICVYWVMRYARKVRNSPESSIVADKMAENQAHFLGNRSETMLEFTPTRKAILILFAASFAFMIYGVAVLGWWMAEISAVFLAAAVIVGVIARMGEETFTSTFIDGARDLLGVALIIGIARGIVVVMDNGMITHTILHSAENLVSGLSTTVFINVTYWLEVLLSFLVPSSSGLAVLTMPIMAPLADFAHVQRDLVVTAYQSASGVVNLITPTSAVVMGGLAIARVPWVRYLRWVAPLLLILTMLNMIVLSIAAMI
>NC_008253.1|WP_000397144.1|4723174_4724686_-|leucyl-aminopeptidase
MEFSVKSGSPEKQRSACIVVGVFEPRRLSPIAEQLDKISDGYISALLRRGELEGKPGQTLLLHHVPNVLSERILLIGCGKERELDERQYKQVIQKTINTLNDTGSMEAVCFLTELHVKGRNNYWKVRQAVETAKETLYSFDQLKTNKSEPRRPLRKMVFNVPTRRELTSGERAIQHGLAIAAGIKAAKDLGNMPPNICNAAYLASQARQLADSYSKNVITRVIGEQQMKELGMHSYLAVGQGSQNESLMSVIEYKGNASEDARPIVLVGKGLTFDSGGISIKPSEGMDEMKYDMCGAAAVYGVMRMVAELQLPINVIGVLAGCENMPGGRAYRPGDVLTTMSGQTVEVLNTDAEGRLVLCDVLTYVERFEPEAVIDVATLTGACVIALGHHITGLMANHNPLAHELIAASEQSGDRAWRLPLGDEYQEQLESNFADMANIGGRPGGAITAGCFLSRFTRKYNWAHLDIAGTAWRSGKAKGATGRPVALLAQFLLNRAGFNGEE
>NC_008253.1|WP_000584114.1|4724952_4726053_+|LPS-export-ABC-transporter-permease-LptF
MIIIRYLVRETLKSQLAILFILLLIFFCQKLVRILGAAVDGDIPANLVLSLLGLGVPEMAQLILPLSLFLGLLMTLGKLYTESEITVMHACGLSKAVLVKAAMILAVFTAIVAAVNVMWAGPWSSRHQDEVLAEAKANPGMAALAQGQFQQATNGSSVLFIESVDGSDFKDVFLAQIRPKGNARPSVVVADSGHLTQLRDGSQVVTLNQGTRFEGTALLRDFRITDFQDYQAIIGHQAVALDPNDTDQMDMRTLWNTDTDRARAELNWRITLVFTVFMMALMVVPLSVVNPRQGRVLSMLPAMLLYLLFFLIQTSLKSNGGKGKLDPTLWMWTVNLIYLALAIVLNLWDTVPVRRLRASFSRKGAV
>NC_008253.1|WP_001295681.1|4726052_4727135_+|LPS-export-ABC-transporter-permease-LptG
MQPFGVLDRYIGKTIFTTIMMTLFMLVSLSGIIKFVDQLKKAGQGSYDALGAGMYTLLSVPKDVQIFFPMAALLGALLGLGMLAQRSELVVMQASGFTRMQVALSVMKTAIPLVLLTMAIGEWVAPQGEQMARNYRAQAMYGGSLLSTQQGLWAKDGNNFVYIERVKGDEELGGISIYAFNENRRLQSVRYAATAKFDPEHKVWRLSQVDESDLTNPKQITGSQTVSGTWKTNLTPDKLGVVALDPDALSISGLHNYVKYLKSSGQDAGRYQLNMWSKIFQPLSVAVMMLMALSFIFGPLRSVPMGVRVVTGISFGFVFYVLDQIFGPLTLVYGIPPIIGALLPSASFFLISLWLLMRKS
>NC_008253.1|WP_001294541.1|4727295_4728798_-|DUF853-domain-containing-protein
MSEPLLIARTPDTELFLLPGMANRHGLITGATGTGKTVTLQKLAESLSEIGVPVFMADVKGDLTGIAQAGTASEKLLARLKNIGVNDWQPHANPVVVWDIFGEKGHPVRATVSDLGPLLLARLLNLNDVQSGVLNIIFRIADDQGLLLLDFKDLRAITQYIGDNAKSFQNQYGNISSASVGAIQRGLLSLEQQGAAHFFGEPMLDIKDWMRTDANGKGVINILSAEKLYQMPKLYAASLLWMLSELYEQLPEAGDLEKPRLVFFFDEAHLLFNDAPQVLLDKIEQVIRLIRSKGVGVWFVSQNPSDIPDNVLGQLGNRVQHALRAFTPKDQKAVKAAAQTMRANPAFDTEKAIQELGTGEALISFLDAKGSPSVVERAMVIAPCSRMGPVTEDERNGLINHSPVYGKYEDDVDRESAYEMLQKGVQASTEQQNNPAVKGKEVAVDDGILGGLKDILFGTTGPRGGKKDGVVQTMAKSAARQVTNQIVRGMLGSLLGGRRR
>NC_008253.1|WP_011579311.1|4728875_4729874_-|DNA-binding-transcriptional-regulator-IdnR
MRNHRISLQDIATLAGVTKMTVSRYIRSPKKVAKETGERIAKIMEEINYIPNRAPGMLLNAQSYTLGILIPSFQNQLFADILAGIESVTSVHNYQTIIANYNYDRDSEEESVINLLSYNIDGIILSEKYHTIRTVKFLRSATIPVVELMDVQGERLDMEVGFDNRQAAFDMVCTMLEKRVRHKILYLGSKDDTRDEQRYQGYCDAMMLHNLSPLRMNPRAISSIHLGMQLMRDALSANPDLDGVFCTNDDIAMGALLLCRERKLAVPEQISIAGFHGLEIGRQMIPSLASVITPRFDIGRTAAQMLLSKIKNNDHKHNTVDLGYQIYHGNTL
>NC_008253.1|WP_001128336.1|4729940_4731260_-|gnt-II-system-L-idonate-transporter
MPLIIIAAGVALLLILMIGFKVNGFIALVLVAAVVGFAEGMDAQAVLHSIQNGIGSTLGGLAMILGFGAMLGKLISDTGAAQRIATTLIATFGKKRVQWALVITGLVVGLAMFFEVGFVLLLPLVFTIVASSGLPLLYVGVPMVAALSVTHCFLPPHPGPTAIATIFEANLGTTLLYGFIITIPTVIVAGPLFSKLLTRFEKAPPEGLFNPHLFSEEEMPSFWNSIFAAVIPVILMAIAAVCEITLPKTNTVRLFFEFVGNPAVALFIAIVIAIFTLGRRNGRTIEQIMDIIGDSIGAIAMIVFIIAGGGAFKQVLVDSGVGQYISHLMTGTTLSPLLMCWTVAALLRIALGSATVAAITTAGVVLPIINVTHADPALMVLATGAGSVIASHVNDPGFWLFKGYFNLTVGETLRTWTVMETLISIMGLLGVLAINAVLH
>NC_008253.1|WP_000998702.1|4731324_4732089_-|gluconate-5-dehydrogenase
MNDLFSLAGKNILITGSAQGIGFLLATGLGKYGAQIIINDITAERAELAVKKLHQEGIQAVAAPFNVTHKHEIDAAVEHIEKDIGPIDVLVNNAGIQRRHPFTEFPEQEWNDVIAVNQTAVFLVSQAVTRHMVERKAGKVINICSMQSELGRDTITPYAASKGAVKMLTRGMCVELARHNIQVNGIAPGYFKTEMTKALVEDEAFTAWLCKRTPAARWGDPQELIGAAVFLSSKASDFVNGHLLFVDGGMLVAV
>NC_008253.1|WP_001197423.1|4732112_4733144_-|L-idonate-5-dehydrogenase
MQVKTQSCVVAGKKTVAVTEQTIDWNNNGTLVQITRGGICGSDLHYYQEGKVGNFMIKAPMVLGHEVIGKVIHSDSSKLHEGQTVAINPSKPCGHCKYCIEHNENQCTEMRFFGSAMYFPHVDGGFTRYKMVETSQCVPYPAKADEKVMAFAEPLAVAIHAAHQAGELQGKRVFISGVGPIGCLIVSAVKTLGAAEIVCADVSPRSLSLGKEMGADVLVNPQNDDMDHWKAEKGYFDVSFEVSGHPSSVNTCLEVTRARGVMVQVGMGGAMAEFPMMTLIGKEISLKGSFRFTSEFNTAVSWLANGVINPLPLLSAEYPFTDLEEALRFAGDKTQAAKVQLVF
>NC_008253.1|WP_001298045.1|4733931_4734951_-|NADPH-dependent-aldehyde-reductase-Ahr
MSMIKSYAAKEAGGELEVYEYDPGELKPQDVEVQVDYCGICHSDLSMIDNEWGFSQYPLVAGHEVIGRVVALGSAAQDKGLQVGQRVGIGWTARSCGHCDACISGNQINCEQGAVPTIMNRGGFAEKLRADWQWVIPLPENIDIESAGPLLCGGITVFKPLLMHHITATSRVGVIGIGGLGHIAIKLLHAMGCEVTAFSSNPAKEQEVLAMGADKVVNSRDPQALKTLAGQFDLIINTVNVSLDWQPYFEALTYGGNFHTVGAVLTPLPVPAFTLIAGDRSVSGSATGTPYELRKLMRFAARSKVAPTTELFPMSKINDAIQHVRDGKARYRVVLKADF
>NC_008253.1|WP_001219008.1|4735417_4736680_+|integrase-arm-type-DNA-binding-domain-containing-protein
MALTDLKVRTAKPADKQYKLTDGGGMHLLVHPNGSKYWRLQYRYEGKQKMLALGVYPEITLADARVRRDEARKLLANGVDPGDKKKNDKVEQSKARTFKEVAIEWYGTNKKWSEDHAHRVLKSLEDNLFAALGERNIAELKTRDLLAPIKAVEMSGRLEVAARLQQRTTAIMRYAVQSGLIDYNPAQEMAGAVASCNRQHRPALELKRIPELLTKIDSYTGRPLTRWATELTLLIFIRSSELRFARWSEIDFEASIWTIPPEREPIPGVKHSHRGSKMRTTHLVPLSRQALAILKQIKQFCGAHDLIFIGNHDSHKPMSENTVNSALRVMGYDTKVEVCGHGFRTMACSSLIESGLWSRDAVERQMSHMERNSVRAAYIHKAEHLEERRLMLQWWADFLDANREKGISPFEYAKINNPLK

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NC_008253_6	6.1\|4293929\|57\|NC_008253\|CRISPRCasFinder	4293929-4293985	57	MT230402	Escherichia coli strain DH5alpha plasmid pESBL87, complete sequence	271-327	5	0.912
NC_008253_3	3.2\|939574\|32\|NC_008253\|CRISPRCasFinder	939574-939605	32	NC_015163	Deinococcus proteolyticus MRP plasmid pDEIPR04, complete sequence	83332-83363	8	0.75
NC_008253_2	2.1\|777716\|48\|NC_008253\|CRISPRCasFinder	777716-777763	48	NZ_AP023208	Escherichia coli strain TUM18781 plasmid pMTY18781-3, complete sequence	12111-12158	9	0.812
NC_008253_2	2.1\|777716\|48\|NC_008253\|CRISPRCasFinder	777716-777763	48	LR134125	Klebsiella aerogenes strain NCTC10006 genome assembly, plasmid: 5	424237-424284	9	0.812
NC_008253_5	5.2\|4233399\|56\|NC_008253\|PILER-CR	4233399-4233454	56	NZ_CP044308	Escherichia coli strain C27A plasmid pC27A-3, complete sequence	13988-14043	9	0.839
NC_008253_2	2.1\|777716\|48\|NC_008253\|CRISPRCasFinder	777716-777763	48	NZ_CP044147	Escherichia coli O157 strain AR-0428 plasmid pAR-0428-2	7391-7438	11	0.771
NC_008253_2	2.1\|777716\|48\|NC_008253\|CRISPRCasFinder	777716-777763	48	CP044351	Escherichia coli strain 194195 plasmid p194195_1, complete sequence	84215-84262	11	0.771
NC_008253_2	2.1\|777716\|48\|NC_008253\|CRISPRCasFinder	777716-777763	48	NZ_AP023206	Escherichia coli strain TUM18781 plasmid pMTY18781-1_lncX3, complete sequence	87125-87172	11	0.771
NC_008253_2	2.1\|777716\|48\|NC_008253\|CRISPRCasFinder	777716-777763	48	NZ_CP019246	Escherichia coli strain Combat13F7 plasmid pCombat13F7-1, complete sequence	41414-41461	11	0.771
NC_008253_5	5.2\|4233399\|56\|NC_008253\|PILER-CR	4233399-4233454	56	NZ_AP023206	Escherichia coli strain TUM18781 plasmid pMTY18781-1_lncX3, complete sequence	87116-87171	11	0.804
NC_008253_7	7.1\|4723063\|52\|NC_008253\|CRISPRCasFinder	4723063-4723114	52	NZ_AP023208	Escherichia coli strain TUM18781 plasmid pMTY18781-3, complete sequence	12113-12164	11	0.788
NC_008253_7	7.1\|4723063\|52\|NC_008253\|CRISPRCasFinder	4723063-4723114	52	MT230402	Escherichia coli strain DH5alpha plasmid pESBL87, complete sequence	272-323	11	0.788
NC_008253_7	7.1\|4723063\|52\|NC_008253\|CRISPRCasFinder	4723063-4723114	52	NZ_AP023207	Escherichia coli strain TUM18781 plasmid pMTY18781-2, complete sequence	31252-31303	11	0.788
NC_008253_2	2.1\|777716\|48\|NC_008253\|CRISPRCasFinder	777716-777763	48	NZ_CP053606	Escherichia coli strain NEB_Turbo plasmid F', complete sequence	229237-229284	12	0.75
NC_008253_2	2.1\|777716\|48\|NC_008253\|CRISPRCasFinder	777716-777763	48	NZ_CP053606	Escherichia coli strain NEB_Turbo plasmid F', complete sequence	229338-229385	12	0.75
NC_008253_2	2.1\|777716\|48\|NC_008253\|CRISPRCasFinder	777716-777763	48	NZ_CP053606	Escherichia coli strain NEB_Turbo plasmid F', complete sequence	229439-229486	12	0.75
NC_008253_2	2.1\|777716\|48\|NC_008253\|CRISPRCasFinder	777716-777763	48	NZ_CP053608	Escherichia coli strain NEB5-alpha_F'Iq plasmid F'Iq, complete sequence	239731-239778	12	0.75
NC_008253_2	2.1\|777716\|48\|NC_008253\|CRISPRCasFinder	777716-777763	48	NZ_CP053608	Escherichia coli strain NEB5-alpha_F'Iq plasmid F'Iq, complete sequence	239832-239879	12	0.75
NC_008253_2	2.1\|777716\|48\|NC_008253\|CRISPRCasFinder	777716-777763	48	NZ_CP053608	Escherichia coli strain NEB5-alpha_F'Iq plasmid F'Iq, complete sequence	239933-239980	12	0.75
NC_008253_2	2.1\|777716\|48\|NC_008253\|CRISPRCasFinder	777716-777763	48	NZ_CP044307	Escherichia coli strain C27A plasmid pC27A-2, complete sequence	15006-15053	12	0.75
NC_008253_2	2.1\|777716\|48\|NC_008253\|CRISPRCasFinder	777716-777763	48	NZ_CP014271	Escherichia coli K-12 strain K-12 DHB4 plasmid F128-(DHB4), complete sequence	230643-230690	12	0.75
NC_008253_2	2.1\|777716\|48\|NC_008253\|CRISPRCasFinder	777716-777763	48	NZ_CP014271	Escherichia coli K-12 strain K-12 DHB4 plasmid F128-(DHB4), complete sequence	230744-230791	12	0.75
NC_008253_2	2.1\|777716\|48\|NC_008253\|CRISPRCasFinder	777716-777763	48	NZ_CP014271	Escherichia coli K-12 strain K-12 DHB4 plasmid F128-(DHB4), complete sequence	230845-230892	12	0.75
NC_008253_2	2.1\|777716\|48\|NC_008253\|CRISPRCasFinder	777716-777763	48	NZ_CP014273	Escherichia coli K-12 strain K-12 C3026 plasmid F128-(C3026), complete sequence	211613-211660	12	0.75
NC_008253_2	2.1\|777716\|48\|NC_008253\|CRISPRCasFinder	777716-777763	48	NZ_CP014273	Escherichia coli K-12 strain K-12 C3026 plasmid F128-(C3026), complete sequence	211714-211761	12	0.75
NC_008253_2	2.1\|777716\|48\|NC_008253\|CRISPRCasFinder	777716-777763	48	NZ_CP014273	Escherichia coli K-12 strain K-12 C3026 plasmid F128-(C3026), complete sequence	211815-211862	12	0.75
NC_008253_2	2.1\|777716\|48\|NC_008253\|CRISPRCasFinder	777716-777763	48	NZ_AP023207	Escherichia coli strain TUM18781 plasmid pMTY18781-2, complete sequence	31250-31297	12	0.75
NC_008253_6	6.1\|4293929\|57\|NC_008253\|CRISPRCasFinder	4293929-4293985	57	NZ_CP010208	Escherichia coli strain M11 plasmid B, complete sequence	30155-30211	12	0.789
NC_008253_2	2.1\|777716\|48\|NC_008253\|CRISPRCasFinder	777716-777763	48	NZ_CP053606	Escherichia coli strain NEB_Turbo plasmid F', complete sequence	3371-3418	13	0.729
NC_008253_2	2.1\|777716\|48\|NC_008253\|CRISPRCasFinder	777716-777763	48	NZ_CP053606	Escherichia coli strain NEB_Turbo plasmid F', complete sequence	4012-4059	13	0.729
NC_008253_2	2.1\|777716\|48\|NC_008253\|CRISPRCasFinder	777716-777763	48	NZ_CP053606	Escherichia coli strain NEB_Turbo plasmid F', complete sequence	4113-4160	13	0.729
NC_008253_2	2.1\|777716\|48\|NC_008253\|CRISPRCasFinder	777716-777763	48	NZ_CP053606	Escherichia coli strain NEB_Turbo plasmid F', complete sequence	208980-209027	13	0.729
NC_008253_2	2.1\|777716\|48\|NC_008253\|CRISPRCasFinder	777716-777763	48	NZ_CP053608	Escherichia coli strain NEB5-alpha_F'Iq plasmid F'Iq, complete sequence	3370-3417	13	0.729
NC_008253_2	2.1\|777716\|48\|NC_008253\|CRISPRCasFinder	777716-777763	48	NZ_CP053608	Escherichia coli strain NEB5-alpha_F'Iq plasmid F'Iq, complete sequence	4011-4058	13	0.729
NC_008253_2	2.1\|777716\|48\|NC_008253\|CRISPRCasFinder	777716-777763	48	NZ_CP053608	Escherichia coli strain NEB5-alpha_F'Iq plasmid F'Iq, complete sequence	4112-4159	13	0.729
NC_008253_2	2.1\|777716\|48\|NC_008253\|CRISPRCasFinder	777716-777763	48	NZ_CP053608	Escherichia coli strain NEB5-alpha_F'Iq plasmid F'Iq, complete sequence	219474-219521	13	0.729
NC_008253_2	2.1\|777716\|48\|NC_008253\|CRISPRCasFinder	777716-777763	48	NZ_CP014271	Escherichia coli K-12 strain K-12 DHB4 plasmid F128-(DHB4), complete sequence	3370-3417	13	0.729
NC_008253_2	2.1\|777716\|48\|NC_008253\|CRISPRCasFinder	777716-777763	48	NZ_CP014271	Escherichia coli K-12 strain K-12 DHB4 plasmid F128-(DHB4), complete sequence	4011-4058	13	0.729
NC_008253_2	2.1\|777716\|48\|NC_008253\|CRISPRCasFinder	777716-777763	48	NZ_CP014271	Escherichia coli K-12 strain K-12 DHB4 plasmid F128-(DHB4), complete sequence	4112-4159	13	0.729
NC_008253_2	2.1\|777716\|48\|NC_008253\|CRISPRCasFinder	777716-777763	48	NZ_CP014271	Escherichia coli K-12 strain K-12 DHB4 plasmid F128-(DHB4), complete sequence	210308-210355	13	0.729
NC_008253_2	2.1\|777716\|48\|NC_008253\|CRISPRCasFinder	777716-777763	48	NZ_CP014273	Escherichia coli K-12 strain K-12 C3026 plasmid F128-(C3026), complete sequence	3370-3417	13	0.729
NC_008253_2	2.1\|777716\|48\|NC_008253\|CRISPRCasFinder	777716-777763	48	NZ_CP014273	Escherichia coli K-12 strain K-12 C3026 plasmid F128-(C3026), complete sequence	4011-4058	13	0.729
NC_008253_2	2.1\|777716\|48\|NC_008253\|CRISPRCasFinder	777716-777763	48	NZ_CP014273	Escherichia coli K-12 strain K-12 C3026 plasmid F128-(C3026), complete sequence	4112-4159	13	0.729
NC_008253_2	2.1\|777716\|48\|NC_008253\|CRISPRCasFinder	777716-777763	48	NZ_CP014273	Escherichia coli K-12 strain K-12 C3026 plasmid F128-(C3026), complete sequence	191263-191310	13	0.729
NC_008253_2	2.1\|777716\|48\|NC_008253\|CRISPRCasFinder	777716-777763	48	MT230402	Escherichia coli strain DH5alpha plasmid pESBL87, complete sequence	270-317	13	0.729
NC_008253_6	6.1\|4293929\|57\|NC_008253\|CRISPRCasFinder	4293929-4293985	57	NZ_CP053606	Escherichia coli strain NEB_Turbo plasmid F', complete sequence	43-99	13	0.772
NC_008253_6	6.1\|4293929\|57\|NC_008253\|CRISPRCasFinder	4293929-4293985	57	NZ_CP053608	Escherichia coli strain NEB5-alpha_F'Iq plasmid F'Iq, complete sequence	42-98	13	0.772
NC_008253_6	6.1\|4293929\|57\|NC_008253\|CRISPRCasFinder	4293929-4293985	57	NZ_CP044307	Escherichia coli strain C27A plasmid pC27A-2, complete sequence	18328-18384	13	0.772
NC_008253_6	6.1\|4293929\|57\|NC_008253\|CRISPRCasFinder	4293929-4293985	57	NZ_CP014271	Escherichia coli K-12 strain K-12 DHB4 plasmid F128-(DHB4), complete sequence	42-98	13	0.772
NC_008253_6	6.1\|4293929\|57\|NC_008253\|CRISPRCasFinder	4293929-4293985	57	NZ_CP014273	Escherichia coli K-12 strain K-12 C3026 plasmid F128-(C3026), complete sequence	42-98	13	0.772
NC_008253_7	7.1\|4723063\|52\|NC_008253\|CRISPRCasFinder	4723063-4723114	52	NZ_CP053606	Escherichia coli strain NEB_Turbo plasmid F', complete sequence	208982-209033	13	0.75
NC_008253_7	7.1\|4723063\|52\|NC_008253\|CRISPRCasFinder	4723063-4723114	52	NZ_CP053608	Escherichia coli strain NEB5-alpha_F'Iq plasmid F'Iq, complete sequence	219476-219527	13	0.75
NC_008253_7	7.1\|4723063\|52\|NC_008253\|CRISPRCasFinder	4723063-4723114	52	NZ_CP014271	Escherichia coli K-12 strain K-12 DHB4 plasmid F128-(DHB4), complete sequence	210310-210361	13	0.75
NC_008253_7	7.1\|4723063\|52\|NC_008253\|CRISPRCasFinder	4723063-4723114	52	NZ_CP014273	Escherichia coli K-12 strain K-12 C3026 plasmid F128-(C3026), complete sequence	191265-191316	13	0.75
NC_008253_2	2.1\|777716\|48\|NC_008253\|CRISPRCasFinder	777716-777763	48	MT230312	Escherichia coli strain DH5alpha plasmid pESBL31, complete sequence	158-205	14	0.708
NC_008253_6	6.1\|4293929\|57\|NC_008253\|CRISPRCasFinder	4293929-4293985	57	NZ_AP023206	Escherichia coli strain TUM18781 plasmid pMTY18781-1_lncX3, complete sequence	87115-87171	14	0.754
NC_008253_6	6.1\|4293929\|57\|NC_008253\|CRISPRCasFinder	4293929-4293985	57	NZ_CP053606	Escherichia coli strain NEB_Turbo plasmid F', complete sequence	229227-229283	14	0.754
NC_008253_6	6.1\|4293929\|57\|NC_008253\|CRISPRCasFinder	4293929-4293985	57	NZ_CP053606	Escherichia coli strain NEB_Turbo plasmid F', complete sequence	229328-229384	14	0.754
NC_008253_6	6.1\|4293929\|57\|NC_008253\|CRISPRCasFinder	4293929-4293985	57	NZ_CP053606	Escherichia coli strain NEB_Turbo plasmid F', complete sequence	229429-229485	14	0.754
NC_008253_6	6.1\|4293929\|57\|NC_008253\|CRISPRCasFinder	4293929-4293985	57	NZ_CP053606	Escherichia coli strain NEB_Turbo plasmid F', complete sequence	4114-4170	14	0.754
NC_008253_6	6.1\|4293929\|57\|NC_008253\|CRISPRCasFinder	4293929-4293985	57	NZ_CP053608	Escherichia coli strain NEB5-alpha_F'Iq plasmid F'Iq, complete sequence	239721-239777	14	0.754
NC_008253_6	6.1\|4293929\|57\|NC_008253\|CRISPRCasFinder	4293929-4293985	57	NZ_CP053608	Escherichia coli strain NEB5-alpha_F'Iq plasmid F'Iq, complete sequence	239822-239878	14	0.754
NC_008253_6	6.1\|4293929\|57\|NC_008253\|CRISPRCasFinder	4293929-4293985	57	NZ_CP053608	Escherichia coli strain NEB5-alpha_F'Iq plasmid F'Iq, complete sequence	239923-239979	14	0.754
NC_008253_6	6.1\|4293929\|57\|NC_008253\|CRISPRCasFinder	4293929-4293985	57	NZ_CP053608	Escherichia coli strain NEB5-alpha_F'Iq plasmid F'Iq, complete sequence	4113-4169	14	0.754
NC_008253_6	6.1\|4293929\|57\|NC_008253\|CRISPRCasFinder	4293929-4293985	57	NZ_CP014271	Escherichia coli K-12 strain K-12 DHB4 plasmid F128-(DHB4), complete sequence	230633-230689	14	0.754
NC_008253_6	6.1\|4293929\|57\|NC_008253\|CRISPRCasFinder	4293929-4293985	57	NZ_CP014271	Escherichia coli K-12 strain K-12 DHB4 plasmid F128-(DHB4), complete sequence	230734-230790	14	0.754
NC_008253_6	6.1\|4293929\|57\|NC_008253\|CRISPRCasFinder	4293929-4293985	57	NZ_CP014271	Escherichia coli K-12 strain K-12 DHB4 plasmid F128-(DHB4), complete sequence	230835-230891	14	0.754
NC_008253_6	6.1\|4293929\|57\|NC_008253\|CRISPRCasFinder	4293929-4293985	57	NZ_CP014271	Escherichia coli K-12 strain K-12 DHB4 plasmid F128-(DHB4), complete sequence	4113-4169	14	0.754
NC_008253_6	6.1\|4293929\|57\|NC_008253\|CRISPRCasFinder	4293929-4293985	57	NZ_CP014273	Escherichia coli K-12 strain K-12 C3026 plasmid F128-(C3026), complete sequence	211603-211659	14	0.754
NC_008253_6	6.1\|4293929\|57\|NC_008253\|CRISPRCasFinder	4293929-4293985	57	NZ_CP014273	Escherichia coli K-12 strain K-12 C3026 plasmid F128-(C3026), complete sequence	211704-211760	14	0.754
NC_008253_6	6.1\|4293929\|57\|NC_008253\|CRISPRCasFinder	4293929-4293985	57	NZ_CP014273	Escherichia coli K-12 strain K-12 C3026 plasmid F128-(C3026), complete sequence	211805-211861	14	0.754
NC_008253_6	6.1\|4293929\|57\|NC_008253\|CRISPRCasFinder	4293929-4293985	57	NZ_CP014273	Escherichia coli K-12 strain K-12 C3026 plasmid F128-(C3026), complete sequence	4113-4169	14	0.754
NC_008253_6	6.1\|4293929\|57\|NC_008253\|CRISPRCasFinder	4293929-4293985	57	NZ_CP044147	Escherichia coli O157 strain AR-0428 plasmid pAR-0428-2	7392-7448	14	0.754
NC_008253_6	6.1\|4293929\|57\|NC_008253\|CRISPRCasFinder	4293929-4293985	57	CP044351	Escherichia coli strain 194195 plasmid p194195_1, complete sequence	84216-84272	14	0.754
NC_008253_5	5.1\|4233300\|63\|NC_008253\|PILER-CR	4233300-4233362	63	NZ_AP023206	Escherichia coli strain TUM18781 plasmid pMTY18781-1_lncX3, complete sequence	87115-87177	15	0.762

1. spacer 6.1|4293929|57|NC_008253|CRISPRCasFinder matches to MT230402 (Escherichia coli strain DH5alpha plasmid pESBL87, complete sequence) position: , mismatch: 5, identity: 0.912

atcaatgcctgatgcgacgctgtcgcgtcttatcaggcctac-aactattgccgacct	CRISPR spacer
atcaatgcctgatgcgacgctgtcgcgtcttatcaggcctacaaaccgttaccgact-	Protospacer
****************************************** ***..**.*****.

2. spacer 3.2|939574|32|NC_008253|CRISPRCasFinder matches to NC_015163 (Deinococcus proteolyticus MRP plasmid pDEIPR04, complete sequence) position: , mismatch: 8, identity: 0.75

ttgccgcggatcctgtctgccaataatgacaa	CRISPR spacer
ctggacggcatcctgtctgccaattttgacaa	Protospacer
.**    * ***************  ******

3. spacer 2.1|777716|48|NC_008253|CRISPRCasFinder matches to NZ_AP023208 (Escherichia coli strain TUM18781 plasmid pMTY18781-3, complete sequence) position: , mismatch: 9, identity: 0.812

aaaccgtaggcctgataagacgcgcaagcgtcgcatcaggtaaacagc	CRISPR spacer
gactcgtaggcctgataagacgcgccagcgtcgcatcaggcaccgaac	Protospacer
.* .********************* **************.*   *.*

4. spacer 2.1|777716|48|NC_008253|CRISPRCasFinder matches to LR134125 (Klebsiella aerogenes strain NCTC10006 genome assembly, plasmid: 5) position: , mismatch: 9, identity: 0.812

aaaccgtaggcctgataagacgcgcaagcgtcg-catcaggtaaacagc	CRISPR spacer
aacctgtaggcctgataagacgcgcaagcgtcgccatcaggcatctca-	Protospacer
** *.**************************** *******.*  . .

5. spacer 5.2|4233399|56|NC_008253|PILER-CR matches to NZ_CP044308 (Escherichia coli strain C27A plasmid pC27A-3, complete sequence) position: , mismatch: 9, identity: 0.839

tacag-tgcccgatgcgacgctgccgcgtcttatcgggcctacaaa-agttctgaacc	CRISPR spacer
-acggatgcccgatgcgacgctggcgcgtcttatcgggcctacaaacggccccgaat-	Protospacer
 **.* ***************** ********************** .*..*.***.

6. spacer 2.1|777716|48|NC_008253|CRISPRCasFinder matches to NZ_CP044147 (Escherichia coli O157 strain AR-0428 plasmid pAR-0428-2) position: , mismatch: 11, identity: 0.771

aaaccgtaggcctgataagacgcgcaagcgtcgcatcaggtaaacagc	CRISPR spacer
gttttgtaggcatgataagacgcgccagcgtcgcatcaggcatccggc	Protospacer
.  ..****** ************* **************.*  *.**

7. spacer 2.1|777716|48|NC_008253|CRISPRCasFinder matches to CP044351 (Escherichia coli strain 194195 plasmid p194195_1, complete sequence) position: , mismatch: 11, identity: 0.771

aaaccgtaggcctgataagacgcgcaagcgtcgcatcaggtaaacagc	CRISPR spacer
gttttgtaggcatgataagacgcgccagcgtcgcatcaggcatccggc	Protospacer
.  ..****** ************* **************.*  *.**

8. spacer 2.1|777716|48|NC_008253|CRISPRCasFinder matches to NZ_AP023206 (Escherichia coli strain TUM18781 plasmid pMTY18781-1_lncX3, complete sequence) position: , mismatch: 11, identity: 0.771

aaaccgtaggcctgataagacgcgcaagcgtcgcatcaggtaaacagc	CRISPR spacer
attttgtaggcctgataagacgcggcagcgtcgcatcaggcatcgtgc	Protospacer
*  ..*******************  **************.*    **

9. spacer 2.1|777716|48|NC_008253|CRISPRCasFinder matches to NZ_CP019246 (Escherichia coli strain Combat13F7 plasmid pCombat13F7-1, complete sequence) position: , mismatch: 11, identity: 0.771

aaaccgtaggcctgataagacgcgcaagcgtcgcatcaggtaaacagc-	CRISPR spacer
gttttgtaggtctgataagacgcgccagcgtcgcatcagac-atcagca	Protospacer
.  ..*****.************** *************.. * ****

10. spacer 5.2|4233399|56|NC_008253|PILER-CR matches to NZ_AP023206 (Escherichia coli strain TUM18781 plasmid pMTY18781-1_lncX3, complete sequence) position: , mismatch: 11, identity: 0.804

tacagtgcccgatgcgacgctgccgcgtcttatcgggcctacaaaagttctgaacc----	CRISPR spacer
cacgatgcctgatgcgacgctgccgcgtcttatcaggcctacaaaa----tcaatcgctt	Protospacer
.**..****.************************.***********    * **.*

11. spacer 7.1|4723063|52|NC_008253|CRISPRCasFinder matches to NZ_AP023208 (Escherichia coli strain TUM18781 plasmid pMTY18781-3, complete sequence) position: , mismatch: 11, identity: 0.788

gccttgcctgatgcgacgctgtcgcgtctcatcaggcctacgagttcagtgc	CRISPR spacer
tcggtgcctgatgcgacgctggcgcgtcttatcaggcctacgagtcgcccgt	Protospacer
 *  ***************** *******.***************.   .*.

12. spacer 7.1|4723063|52|NC_008253|CRISPRCasFinder matches to MT230402 (Escherichia coli strain DH5alpha plasmid pESBL87, complete sequence) position: , mismatch: 11, identity: 0.788

gccttgcctgatgcgacgctgtcgcgtctcatcaggcctacgagttcagtgc-	CRISPR spacer
tcaatgcctgatgcgacgctgtcgcgtcttatcaggcctacaaa-ccgttacc	Protospacer
 *  *************************.***********.*. .*. *.*

13. spacer 7.1|4723063|52|NC_008253|CRISPRCasFinder matches to NZ_AP023207 (Escherichia coli strain TUM18781 plasmid pMTY18781-2, complete sequence) position: , mismatch: 11, identity: 0.788

gccttgcctgatgcgacgctgtcgcgtctcatcaggcctacgagttcagtgc--	CRISPR spacer
tcaatgcctgatgcgacgctgtcgcgtcttatcaggcctacag--ccgttgcca	Protospacer
 *  *************************.***********..  .*. ***

14. spacer 2.1|777716|48|NC_008253|CRISPRCasFinder matches to NZ_CP053606 (Escherichia coli strain NEB_Turbo plasmid F', complete sequence) position: , mismatch: 12, identity: 0.75

aaaccgtaggcctgataagacgcgcaagcgtcgcatcaggtaaacagc	CRISPR spacer
aatttgtaggcctgataagacgcgttagcgtcgcatcaggcatctgcg	Protospacer
** ..*******************. **************.*  ..

15. spacer 2.1|777716|48|NC_008253|CRISPRCasFinder matches to NZ_CP053606 (Escherichia coli strain NEB_Turbo plasmid F', complete sequence) position: , mismatch: 12, identity: 0.75

aaaccgtaggcctgataagacgcgcaagcgtcgcatcaggtaaacagc	CRISPR spacer
aatttgtaggcctgataagacgcgttagcgtcgcatcaggcatctgcg	Protospacer
** ..*******************. **************.*  ..

16. spacer 2.1|777716|48|NC_008253|CRISPRCasFinder matches to NZ_CP053606 (Escherichia coli strain NEB_Turbo plasmid F', complete sequence) position: , mismatch: 12, identity: 0.75

aaaccgtaggcctgataagacgcgcaagcgtcgcatcaggtaaacagc	CRISPR spacer
aatttgtaggcctgataagacgcgttagcgtcgcatcaggcatctgca	Protospacer
** ..*******************. **************.*  ..

17. spacer 2.1|777716|48|NC_008253|CRISPRCasFinder matches to NZ_CP053608 (Escherichia coli strain NEB5-alpha_F'Iq plasmid F'Iq, complete sequence) position: , mismatch: 12, identity: 0.75

aaaccgtaggcctgataagacgcgcaagcgtcgcatcaggtaaacagc	CRISPR spacer
aatttgtaggcctgataagacgcgttagcgtcgcatcaggcatctgcg	Protospacer
** ..*******************. **************.*  ..

18. spacer 2.1|777716|48|NC_008253|CRISPRCasFinder matches to NZ_CP053608 (Escherichia coli strain NEB5-alpha_F'Iq plasmid F'Iq, complete sequence) position: , mismatch: 12, identity: 0.75

aaaccgtaggcctgataagacgcgcaagcgtcgcatcaggtaaacagc	CRISPR spacer
aatttgtaggcctgataagacgcgttagcgtcgcatcaggcatctgcg	Protospacer
** ..*******************. **************.*  ..

19. spacer 2.1|777716|48|NC_008253|CRISPRCasFinder matches to NZ_CP053608 (Escherichia coli strain NEB5-alpha_F'Iq plasmid F'Iq, complete sequence) position: , mismatch: 12, identity: 0.75

aaaccgtaggcctgataagacgcgcaagcgtcgcatcaggtaaacagc	CRISPR spacer
aatttgtaggcctgataagacgcgttagcgtcgcatcaggcatctgca	Protospacer
** ..*******************. **************.*  ..

20. spacer 2.1|777716|48|NC_008253|CRISPRCasFinder matches to NZ_CP044307 (Escherichia coli strain C27A plasmid pC27A-2, complete sequence) position: , mismatch: 12, identity: 0.75

aaaccgtaggcctgataagacgcgcaagcgtcgcatcaggtaaacagc	CRISPR spacer
ggctcgtaggcatgataagacgcgccagcgtcgcatcaggcacctggt	Protospacer
.. .******* ************* **************.*  ..*.

21. spacer 2.1|777716|48|NC_008253|CRISPRCasFinder matches to NZ_CP014271 (Escherichia coli K-12 strain K-12 DHB4 plasmid F128-(DHB4), complete sequence) position: , mismatch: 12, identity: 0.75

aaaccgtaggcctgataagacgcgcaagcgtcgcatcaggtaaacagc	CRISPR spacer
aatttgtaggcctgataagacgcgttagcgtcgcatcaggcatctgcg	Protospacer
** ..*******************. **************.*  ..

22. spacer 2.1|777716|48|NC_008253|CRISPRCasFinder matches to NZ_CP014271 (Escherichia coli K-12 strain K-12 DHB4 plasmid F128-(DHB4), complete sequence) position: , mismatch: 12, identity: 0.75

aaaccgtaggcctgataagacgcgcaagcgtcgcatcaggtaaacagc	CRISPR spacer
aatttgtaggcctgataagacgcgttagcgtcgcatcaggcatctgcg	Protospacer
** ..*******************. **************.*  ..

23. spacer 2.1|777716|48|NC_008253|CRISPRCasFinder matches to NZ_CP014271 (Escherichia coli K-12 strain K-12 DHB4 plasmid F128-(DHB4), complete sequence) position: , mismatch: 12, identity: 0.75

aaaccgtaggcctgataagacgcgcaagcgtcgcatcaggtaaacagc	CRISPR spacer
aatttgtaggcctgataagacgcgttagcgtcgcatcaggcatctgca	Protospacer
** ..*******************. **************.*  ..

24. spacer 2.1|777716|48|NC_008253|CRISPRCasFinder matches to NZ_CP014273 (Escherichia coli K-12 strain K-12 C3026 plasmid F128-(C3026), complete sequence) position: , mismatch: 12, identity: 0.75

aaaccgtaggcctgataagacgcgcaagcgtcgcatcaggtaaacagc	CRISPR spacer
aatttgtaggcctgataagacgcgttagcgtcgcatcaggcatctgcg	Protospacer
** ..*******************. **************.*  ..

25. spacer 2.1|777716|48|NC_008253|CRISPRCasFinder matches to NZ_CP014273 (Escherichia coli K-12 strain K-12 C3026 plasmid F128-(C3026), complete sequence) position: , mismatch: 12, identity: 0.75

aaaccgtaggcctgataagacgcgcaagcgtcgcatcaggtaaacagc	CRISPR spacer
aatttgtaggcctgataagacgcgttagcgtcgcatcaggcatctgcg	Protospacer
** ..*******************. **************.*  ..

26. spacer 2.1|777716|48|NC_008253|CRISPRCasFinder matches to NZ_CP014273 (Escherichia coli K-12 strain K-12 C3026 plasmid F128-(C3026), complete sequence) position: , mismatch: 12, identity: 0.75

aaaccgtaggcctgataagacgcgcaagcgtcgcatcaggtaaacagc	CRISPR spacer
aatttgtaggcctgataagacgcgttagcgtcgcatcaggcatctgca	Protospacer
** ..*******************. **************.*  ..

27. spacer 2.1|777716|48|NC_008253|CRISPRCasFinder matches to NZ_AP023207 (Escherichia coli strain TUM18781 plasmid pMTY18781-2, complete sequence) position: , mismatch: 12, identity: 0.75

aaaccgtaggcctgataagacgcgcaagcgtcgcatcaggtaaacagc	CRISPR spacer
cggctgtaggcctgataagacgcgacagcgtcgcatcaggcattgatt	Protospacer
 ..*.*******************  **************.*   * .

28. spacer 6.1|4293929|57|NC_008253|CRISPRCasFinder matches to NZ_CP010208 (Escherichia coli strain M11 plasmid B, complete sequence) position: , mismatch: 12, identity: 0.789

atcaatgcctgatgcgacgctgtcgcgtcttatcaggcctacaa-ctattgccgacct	CRISPR spacer
tctgatgcctgatgcgacgctgacgcgtcttatcatgcctacaatctgcacccgaac-	Protospacer
 ...****************** ************ ******** **..  **** *

29. spacer 2.1|777716|48|NC_008253|CRISPRCasFinder matches to NZ_CP053606 (Escherichia coli strain NEB_Turbo plasmid F', complete sequence) position: , mismatch: 13, identity: 0.729

aaaccgtaggcctgataagacgcgcaagcgtcgcatcaggtaaacagc	CRISPR spacer
ggctcgtaggcatgataagacgcgccagcgtcgcatcaggcacctgcg	Protospacer
.. .******* ************* **************.*  ..

30. spacer 2.1|777716|48|NC_008253|CRISPRCasFinder matches to NZ_CP053606 (Escherichia coli strain NEB_Turbo plasmid F', complete sequence) position: , mismatch: 13, identity: 0.729

aaaccgtaggcctgataagacgcgcaagcgtcgcatcaggtaaacagc	CRISPR spacer
agtttgtaggcatgataagacgcgctagcgtcgcatcaggcatctgcg	Protospacer
*. ..****** ************* **************.*  ..

31. spacer 2.1|777716|48|NC_008253|CRISPRCasFinder matches to NZ_CP053606 (Escherichia coli strain NEB_Turbo plasmid F', complete sequence) position: , mismatch: 13, identity: 0.729

aaaccgtaggcctgataagacgcgcaagcgtcgcatcaggtaaacagc	CRISPR spacer
agtttgtaggcatgataagacgcgccagcgtcgcatcaggcatctgcg	Protospacer
*. ..****** ************* **************.*  ..

32. spacer 2.1|777716|48|NC_008253|CRISPRCasFinder matches to NZ_CP053606 (Escherichia coli strain NEB_Turbo plasmid F', complete sequence) position: , mismatch: 13, identity: 0.729

aaaccgtaggcctgataagacgcgcaagcgtcgcatcaggtaaacagc	CRISPR spacer
agtgggtaggcctgataagacgcgtcagcgtcgcatcaggcatctgag	Protospacer
*.   *******************. **************.*  ...

33. spacer 2.1|777716|48|NC_008253|CRISPRCasFinder matches to NZ_CP053608 (Escherichia coli strain NEB5-alpha_F'Iq plasmid F'Iq, complete sequence) position: , mismatch: 13, identity: 0.729

aaaccgtaggcctgataagacgcgcaagcgtcgcatcaggtaaacagc	CRISPR spacer
ggctcgtaggcatgataagacgcgccagcgtcgcatcaggcacctgcg	Protospacer
.. .******* ************* **************.*  ..

34. spacer 2.1|777716|48|NC_008253|CRISPRCasFinder matches to NZ_CP053608 (Escherichia coli strain NEB5-alpha_F'Iq plasmid F'Iq, complete sequence) position: , mismatch: 13, identity: 0.729

aaaccgtaggcctgataagacgcgcaagcgtcgcatcaggtaaacagc	CRISPR spacer
agtttgtaggcatgataagacgcgctagcgtcgcatcaggcatctgcg	Protospacer
*. ..****** ************* **************.*  ..

35. spacer 2.1|777716|48|NC_008253|CRISPRCasFinder matches to NZ_CP053608 (Escherichia coli strain NEB5-alpha_F'Iq plasmid F'Iq, complete sequence) position: , mismatch: 13, identity: 0.729

aaaccgtaggcctgataagacgcgcaagcgtcgcatcaggtaaacagc	CRISPR spacer
agtttgtaggcatgataagacgcgccagcgtcgcatcaggcatctgcg	Protospacer
*. ..****** ************* **************.*  ..

36. spacer 2.1|777716|48|NC_008253|CRISPRCasFinder matches to NZ_CP053608 (Escherichia coli strain NEB5-alpha_F'Iq plasmid F'Iq, complete sequence) position: , mismatch: 13, identity: 0.729

aaaccgtaggcctgataagacgcgcaagcgtcgcatcaggtaaacagc	CRISPR spacer
agtgggtaggcctgataagacgcgtcagcgtcgcatcaggcatctgag	Protospacer
*.   *******************. **************.*  ...

37. spacer 2.1|777716|48|NC_008253|CRISPRCasFinder matches to NZ_CP014271 (Escherichia coli K-12 strain K-12 DHB4 plasmid F128-(DHB4), complete sequence) position: , mismatch: 13, identity: 0.729

aaaccgtaggcctgataagacgcgcaagcgtcgcatcaggtaaacagc	CRISPR spacer
ggctcgtaggcatgataagacgcgccagcgtcgcatcaggcacctgcg	Protospacer
.. .******* ************* **************.*  ..

38. spacer 2.1|777716|48|NC_008253|CRISPRCasFinder matches to NZ_CP014271 (Escherichia coli K-12 strain K-12 DHB4 plasmid F128-(DHB4), complete sequence) position: , mismatch: 13, identity: 0.729

aaaccgtaggcctgataagacgcgcaagcgtcgcatcaggtaaacagc	CRISPR spacer
agtttgtaggcatgataagacgcgctagcgtcgcatcaggcatctgcg	Protospacer
*. ..****** ************* **************.*  ..

39. spacer 2.1|777716|48|NC_008253|CRISPRCasFinder matches to NZ_CP014271 (Escherichia coli K-12 strain K-12 DHB4 plasmid F128-(DHB4), complete sequence) position: , mismatch: 13, identity: 0.729

aaaccgtaggcctgataagacgcgcaagcgtcgcatcaggtaaacagc	CRISPR spacer
agtttgtaggcatgataagacgcgccagcgtcgcatcaggcatctgcg	Protospacer
*. ..****** ************* **************.*  ..

40. spacer 2.1|777716|48|NC_008253|CRISPRCasFinder matches to NZ_CP014271 (Escherichia coli K-12 strain K-12 DHB4 plasmid F128-(DHB4), complete sequence) position: , mismatch: 13, identity: 0.729

aaaccgtaggcctgataagacgcgcaagcgtcgcatcaggtaaacagc	CRISPR spacer
agtgggtaggcctgataagacgcgtcagcgtcgcatcaggcatctgag	Protospacer
*.   *******************. **************.*  ...

41. spacer 2.1|777716|48|NC_008253|CRISPRCasFinder matches to NZ_CP014273 (Escherichia coli K-12 strain K-12 C3026 plasmid F128-(C3026), complete sequence) position: , mismatch: 13, identity: 0.729

aaaccgtaggcctgataagacgcgcaagcgtcgcatcaggtaaacagc	CRISPR spacer
ggctcgtaggcatgataagacgcgccagcgtcgcatcaggcacctgcg	Protospacer
.. .******* ************* **************.*  ..

42. spacer 2.1|777716|48|NC_008253|CRISPRCasFinder matches to NZ_CP014273 (Escherichia coli K-12 strain K-12 C3026 plasmid F128-(C3026), complete sequence) position: , mismatch: 13, identity: 0.729

aaaccgtaggcctgataagacgcgcaagcgtcgcatcaggtaaacagc	CRISPR spacer
agtttgtaggcatgataagacgcgctagcgtcgcatcaggcatctgcg	Protospacer
*. ..****** ************* **************.*  ..

43. spacer 2.1|777716|48|NC_008253|CRISPRCasFinder matches to NZ_CP014273 (Escherichia coli K-12 strain K-12 C3026 plasmid F128-(C3026), complete sequence) position: , mismatch: 13, identity: 0.729

aaaccgtaggcctgataagacgcgcaagcgtcgcatcaggtaaacagc	CRISPR spacer
agtttgtaggcatgataagacgcgccagcgtcgcatcaggcatctgcg	Protospacer
*. ..****** ************* **************.*  ..

44. spacer 2.1|777716|48|NC_008253|CRISPRCasFinder matches to NZ_CP014273 (Escherichia coli K-12 strain K-12 C3026 plasmid F128-(C3026), complete sequence) position: , mismatch: 13, identity: 0.729

aaaccgtaggcctgataagacgcgcaagcgtcgcatcaggtaaacagc	CRISPR spacer
agtgggtaggcctgataagacgcgtcagcgtcgcatcaggcatctgag	Protospacer
*.   *******************. **************.*  ...

45. spacer 2.1|777716|48|NC_008253|CRISPRCasFinder matches to MT230402 (Escherichia coli strain DH5alpha plasmid pESBL87, complete sequence) position: , mismatch: 13, identity: 0.729

aaaccgtaggcctgataagacgcgcaagcgtcgcatcaggtaaacagc	CRISPR spacer
ggtttgtaggcctgataagacgcgacagcgtcgcatcaggcattgatt	Protospacer
.. ..*******************  **************.*   * .

46. spacer 6.1|4293929|57|NC_008253|CRISPRCasFinder matches to NZ_CP053606 (Escherichia coli strain NEB_Turbo plasmid F', complete sequence) position: , mismatch: 13, identity: 0.772

atcaatgcctgatgcgacgctgtcgcgtcttatcaggcctacaa--ctattgccgacct	CRISPR spacer
gctgatgcctgatgcgacgctgacgcgtcttatcatgcctacaaatctgtacgcgaa--	Protospacer
....****************** ************ ********  **.*   ***

47. spacer 6.1|4293929|57|NC_008253|CRISPRCasFinder matches to NZ_CP053608 (Escherichia coli strain NEB5-alpha_F'Iq plasmid F'Iq, complete sequence) position: , mismatch: 13, identity: 0.772

atcaatgcctgatgcgacgctgtcgcgtcttatcaggcctacaa--ctattgccgacct	CRISPR spacer
gctgatgcctgatgcgacgctgacgcgtcttatcatgcctacaaatctgtacgcgaa--	Protospacer
....****************** ************ ********  **.*   ***

48. spacer 6.1|4293929|57|NC_008253|CRISPRCasFinder matches to NZ_CP044307 (Escherichia coli strain C27A plasmid pC27A-2, complete sequence) position: , mismatch: 13, identity: 0.772

atcaatgcctgatgcgacgctgtcgcgtcttatcaggcctacaa--ctattgccgacct	CRISPR spacer
gctgatgcctgatgcgacgctgacgcgtcttatcatgcctacaaatctgtacgcgaa--	Protospacer
....****************** ************ ********  **.*   ***

49. spacer 6.1|4293929|57|NC_008253|CRISPRCasFinder matches to NZ_CP014271 (Escherichia coli K-12 strain K-12 DHB4 plasmid F128-(DHB4), complete sequence) position: , mismatch: 13, identity: 0.772

atcaatgcctgatgcgacgctgtcgcgtcttatcaggcctacaa--ctattgccgacct	CRISPR spacer
gctgatgcctgatgcgacgctgacgcgtcttatcatgcctacaaatctgtacgcgaa--	Protospacer
....****************** ************ ********  **.*   ***

50. spacer 6.1|4293929|57|NC_008253|CRISPRCasFinder matches to NZ_CP014273 (Escherichia coli K-12 strain K-12 C3026 plasmid F128-(C3026), complete sequence) position: , mismatch: 13, identity: 0.772

atcaatgcctgatgcgacgctgtcgcgtcttatcaggcctacaa--ctattgccgacct	CRISPR spacer
gctgatgcctgatgcgacgctgacgcgtcttatcatgcctacaaatctgtacgcgaa--	Protospacer
....****************** ************ ********  **.*   ***

51. spacer 7.1|4723063|52|NC_008253|CRISPRCasFinder matches to NZ_CP053606 (Escherichia coli strain NEB_Turbo plasmid F', complete sequence) position: , mismatch: 13, identity: 0.75

gccttgcctgatgcgacgctgtcgcgtctcatcaggcctacgagttcagtgc----	CRISPR spacer
cagatgcctgatgcgacgctgacgcgtcttatcaggcctac----ccactgttttt	Protospacer
    ***************** *******.***********    .** **.

52. spacer 7.1|4723063|52|NC_008253|CRISPRCasFinder matches to NZ_CP053608 (Escherichia coli strain NEB5-alpha_F'Iq plasmid F'Iq, complete sequence) position: , mismatch: 13, identity: 0.75

gccttgcctgatgcgacgctgtcgcgtctcatcaggcctacgagttcagtgc----	CRISPR spacer
cagatgcctgatgcgacgctgacgcgtcttatcaggcctac----ccactgttttt	Protospacer
    ***************** *******.***********    .** **.

53. spacer 7.1|4723063|52|NC_008253|CRISPRCasFinder matches to NZ_CP014271 (Escherichia coli K-12 strain K-12 DHB4 plasmid F128-(DHB4), complete sequence) position: , mismatch: 13, identity: 0.75

gccttgcctgatgcgacgctgtcgcgtctcatcaggcctacgagttcagtgc----	CRISPR spacer
cagatgcctgatgcgacgctgacgcgtcttatcaggcctac----ccactgttttt	Protospacer
    ***************** *******.***********    .** **.

54. spacer 7.1|4723063|52|NC_008253|CRISPRCasFinder matches to NZ_CP014273 (Escherichia coli K-12 strain K-12 C3026 plasmid F128-(C3026), complete sequence) position: , mismatch: 13, identity: 0.75

gccttgcctgatgcgacgctgtcgcgtctcatcaggcctacgagttcagtgc----	CRISPR spacer
cagatgcctgatgcgacgctgacgcgtcttatcaggcctac----ccactgttttt	Protospacer
    ***************** *******.***********    .** **.

55. spacer 2.1|777716|48|NC_008253|CRISPRCasFinder matches to MT230312 (Escherichia coli strain DH5alpha plasmid pESBL31, complete sequence) position: , mismatch: 14, identity: 0.708

aaaccgtaggcctgataagacgcgcaagcgtcgcatcaggtaaacagc	CRISPR spacer
gtctngtaggcctgataagacgcgtcagcgtcgcatcaggcttcaatt	Protospacer
.  . *******************. **************.    * .

56. spacer 6.1|4293929|57|NC_008253|CRISPRCasFinder matches to NZ_AP023206 (Escherichia coli strain TUM18781 plasmid pMTY18781-1_lncX3, complete sequence) position: , mismatch: 14, identity: 0.754

atcaatgcctgatgcgacgctgtcgcgtcttatcaggcctacaactattgccgacct	CRISPR spacer
cacgatgcctgatgcgacgctgccgcgtcttatcaggcctacaaaatcaatcgcttt	Protospacer
  *.******************.*********************   . ..** ..*

57. spacer 6.1|4293929|57|NC_008253|CRISPRCasFinder matches to NZ_CP053606 (Escherichia coli strain NEB_Turbo plasmid F', complete sequence) position: , mismatch: 14, identity: 0.754

atcaatgcctgatgcgacgctgtcgcgtcttatcaggcctacaactattgccgacct	CRISPR spacer
gcagatgcctgatgcgacgctaacgcgtcttatcaggcctacaaattcccgcgccat	Protospacer
.. .*****************. ********************* * ..  ** * *

58. spacer 6.1|4293929|57|NC_008253|CRISPRCasFinder matches to NZ_CP053606 (Escherichia coli strain NEB_Turbo plasmid F', complete sequence) position: , mismatch: 14, identity: 0.754

atcaatgcctgatgcgacgctgtcgcgtcttatcaggcctacaactattgccgacct	CRISPR spacer
gcagatgcctgatgcgacgctaacgcgtcttatcaggcctacaaattctcgcgccac	Protospacer
.. .*****************. ********************* * .*  ** * .

59. spacer 6.1|4293929|57|NC_008253|CRISPRCasFinder matches to NZ_CP053606 (Escherichia coli strain NEB_Turbo plasmid F', complete sequence) position: , mismatch: 14, identity: 0.754

atcaatgcctgatgcgacgctgtcgcgtcttatcaggcctacaactattgccgacct	CRISPR spacer
gcagatgcctgatgcgacgctaacgcgtcttatcaggcctacaaattcccgcgccat	Protospacer
.. .*****************. ********************* * ..  ** * *

60. spacer 6.1|4293929|57|NC_008253|CRISPRCasFinder matches to NZ_CP053606 (Escherichia coli strain NEB_Turbo plasmid F', complete sequence) position: , mismatch: 14, identity: 0.754

atcaatgcctgatgcgacgctgtcgcgtcttatcaggcctacaa--ctattgccgacct	CRISPR spacer
gcagatgcctgatgcgacgctggcgcgtcttatcatgcctacaaacttgtgcctgaa--	Protospacer
.. .****************** ************ ********  .*.*  *.**

61. spacer 6.1|4293929|57|NC_008253|CRISPRCasFinder matches to NZ_CP053608 (Escherichia coli strain NEB5-alpha_F'Iq plasmid F'Iq, complete sequence) position: , mismatch: 14, identity: 0.754

atcaatgcctgatgcgacgctgtcgcgtcttatcaggcctacaactattgccgacct	CRISPR spacer
gcagatgcctgatgcgacgctaacgcgtcttatcaggcctacaaattcccgcgccat	Protospacer
.. .*****************. ********************* * ..  ** * *

62. spacer 6.1|4293929|57|NC_008253|CRISPRCasFinder matches to NZ_CP053608 (Escherichia coli strain NEB5-alpha_F'Iq plasmid F'Iq, complete sequence) position: , mismatch: 14, identity: 0.754

atcaatgcctgatgcgacgctgtcgcgtcttatcaggcctacaactattgccgacct	CRISPR spacer
gcagatgcctgatgcgacgctaacgcgtcttatcaggcctacaaattctcgcgccac	Protospacer
.. .*****************. ********************* * .*  ** * .

63. spacer 6.1|4293929|57|NC_008253|CRISPRCasFinder matches to NZ_CP053608 (Escherichia coli strain NEB5-alpha_F'Iq plasmid F'Iq, complete sequence) position: , mismatch: 14, identity: 0.754

atcaatgcctgatgcgacgctgtcgcgtcttatcaggcctacaactattgccgacct	CRISPR spacer
gcagatgcctgatgcgacgctaacgcgtcttatcaggcctacaaattcccgcgccat	Protospacer
.. .*****************. ********************* * ..  ** * *

64. spacer 6.1|4293929|57|NC_008253|CRISPRCasFinder matches to NZ_CP053608 (Escherichia coli strain NEB5-alpha_F'Iq plasmid F'Iq, complete sequence) position: , mismatch: 14, identity: 0.754

atcaatgcctgatgcgacgctgtcgcgtcttatcaggcctacaa--ctattgccgacct	CRISPR spacer
gcagatgcctgatgcgacgctggcgcgtcttatcatgcctacaaacttgtgcctgaa--	Protospacer
.. .****************** ************ ********  .*.*  *.**

65. spacer 6.1|4293929|57|NC_008253|CRISPRCasFinder matches to NZ_CP014271 (Escherichia coli K-12 strain K-12 DHB4 plasmid F128-(DHB4), complete sequence) position: , mismatch: 14, identity: 0.754

atcaatgcctgatgcgacgctgtcgcgtcttatcaggcctacaactattgccgacct	CRISPR spacer
gcagatgcctgatgcgacgctaacgcgtcttatcaggcctacaaattcccgcgccat	Protospacer
.. .*****************. ********************* * ..  ** * *

66. spacer 6.1|4293929|57|NC_008253|CRISPRCasFinder matches to NZ_CP014271 (Escherichia coli K-12 strain K-12 DHB4 plasmid F128-(DHB4), complete sequence) position: , mismatch: 14, identity: 0.754

atcaatgcctgatgcgacgctgtcgcgtcttatcaggcctacaactattgccgacct	CRISPR spacer
gcagatgcctgatgcgacgctaacgcgtcttatcaggcctacaaattctcgcgccac	Protospacer
.. .*****************. ********************* * .*  ** * .

67. spacer 6.1|4293929|57|NC_008253|CRISPRCasFinder matches to NZ_CP014271 (Escherichia coli K-12 strain K-12 DHB4 plasmid F128-(DHB4), complete sequence) position: , mismatch: 14, identity: 0.754

atcaatgcctgatgcgacgctgtcgcgtcttatcaggcctacaactattgccgacct	CRISPR spacer
gcagatgcctgatgcgacgctaacgcgtcttatcaggcctacaaattcccgcgccat	Protospacer
.. .*****************. ********************* * ..  ** * *

68. spacer 6.1|4293929|57|NC_008253|CRISPRCasFinder matches to NZ_CP014271 (Escherichia coli K-12 strain K-12 DHB4 plasmid F128-(DHB4), complete sequence) position: , mismatch: 14, identity: 0.754

atcaatgcctgatgcgacgctgtcgcgtcttatcaggcctacaa--ctattgccgacct	CRISPR spacer
gcagatgcctgatgcgacgctggcgcgtcttatcatgcctacaaacttgtgcctgaa--	Protospacer
.. .****************** ************ ********  .*.*  *.**

69. spacer 6.1|4293929|57|NC_008253|CRISPRCasFinder matches to NZ_CP014273 (Escherichia coli K-12 strain K-12 C3026 plasmid F128-(C3026), complete sequence) position: , mismatch: 14, identity: 0.754

atcaatgcctgatgcgacgctgtcgcgtcttatcaggcctacaactattgccgacct	CRISPR spacer
gcagatgcctgatgcgacgctaacgcgtcttatcaggcctacaaattcccgcgccat	Protospacer
.. .*****************. ********************* * ..  ** * *

70. spacer 6.1|4293929|57|NC_008253|CRISPRCasFinder matches to NZ_CP014273 (Escherichia coli K-12 strain K-12 C3026 plasmid F128-(C3026), complete sequence) position: , mismatch: 14, identity: 0.754

atcaatgcctgatgcgacgctgtcgcgtcttatcaggcctacaactattgccgacct	CRISPR spacer
gcagatgcctgatgcgacgctaacgcgtcttatcaggcctacaaattctcgcgccac	Protospacer
.. .*****************. ********************* * .*  ** * .

71. spacer 6.1|4293929|57|NC_008253|CRISPRCasFinder matches to NZ_CP014273 (Escherichia coli K-12 strain K-12 C3026 plasmid F128-(C3026), complete sequence) position: , mismatch: 14, identity: 0.754

atcaatgcctgatgcgacgctgtcgcgtcttatcaggcctacaactattgccgacct	CRISPR spacer
gcagatgcctgatgcgacgctaacgcgtcttatcaggcctacaaattcccgcgccat	Protospacer
.. .*****************. ********************* * ..  ** * *

72. spacer 6.1|4293929|57|NC_008253|CRISPRCasFinder matches to NZ_CP014273 (Escherichia coli K-12 strain K-12 C3026 plasmid F128-(C3026), complete sequence) position: , mismatch: 14, identity: 0.754

atcaatgcctgatgcgacgctgtcgcgtcttatcaggcctacaa--ctattgccgacct	CRISPR spacer
gcagatgcctgatgcgacgctggcgcgtcttatcatgcctacaaacttgtgcctgaa--	Protospacer
.. .****************** ************ ********  .*.*  *.**

73. spacer 6.1|4293929|57|NC_008253|CRISPRCasFinder matches to NZ_CP044147 (Escherichia coli O157 strain AR-0428 plasmid pAR-0428-2) position: , mismatch: 14, identity: 0.754

atcaatgcctgatgcgacgctgtcgcgtcttatcaggcctac--aactattgccgacct	CRISPR spacer
ccggatgcctgatgcgacgctggcgcgtcttatcatgcctacaaaactgcactcaac--	Protospacer
 . .****************** ************ ******  ****..  .*.**

74. spacer 6.1|4293929|57|NC_008253|CRISPRCasFinder matches to CP044351 (Escherichia coli strain 194195 plasmid p194195_1, complete sequence) position: , mismatch: 14, identity: 0.754

atcaatgcctgatgcgacgctgtcgcgtcttatcaggcctac--aactattgccgacct	CRISPR spacer
ccggatgcctgatgcgacgctggcgcgtcttatcatgcctacaaaactgcactcaac--	Protospacer
 . .****************** ************ ******  ****..  .*.**

75. spacer 5.1|4233300|63|NC_008253|PILER-CR matches to NZ_AP023206 (Escherichia coli strain TUM18781 plasmid pMTY18781-1_lncX3, complete sequence) position: , mismatch: 15, identity: 0.762

ttggtgcacgatgcctgatgcgacgctggcgcgtcttatcaggcctacattggtgccgga	CRISPR spacer
tcggtgcacgatgcctgatgcgacgctgccgcgtcttatcaggcctaca--------aaa	Protospacer
*.************************** ********************        ..*

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

253891 : 298326

Enterobacteria_phage(18.18%)

transposase,integrase,plate

attL 259841:259856|attR 304280:304295

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000224521.1\|253891_255238_-\|plate	type VI secretion system baseplate subunit TssK	NA	NA	NA	NA
WP_001013428.1\|255240_255765_-	type VI secretion system lipoprotein TssJ	NA	NA	NA	NA
WP_000433567.1\|255761_257054_-	type VI secretion system-associated FHA domain protein TagH	NA	NA	NA	NA
WP_000896716.1\|257058_258108_-\|plate	type VI secretion system baseplate subunit TssG	NA	NA	NA	NA
WP_000863399.1\|258071_259913_-\|plate	type VI secretion system baseplate subunit TssF	NA	NA	NA	NA
259841:259856	attL	NA	NA	NA	NA
WP_001189667.1\|259918_260344_-\|plate	type VI secretion system baseplate subunit TssE	NA	NA	NA	NA
WP_000111582.1\|260348_261833_-	type VI secretion system contractile sheath large subunit	NA	NA	NA	NA
WP_000041480.1\|261855_262359_-	type VI secretion system contractile sheath small subunit	NA	NA	NA	NA
WP_001142963.1\|263064_263583_+	Hcp family type VI secretion system effector	NA	NA	NA	NA
WP_000053624.1\|263803_265786_+	type VI secretion system tip protein VgrG	A0A077K8Q4	Ralstonia_phage	1.6e-23	25.3
WP_000571853.1\|265892_266939_+	DUF2169 domain-containing protein	NA	NA	NA	NA
WP_000528851.1\|266931_268371_+	DUF4150 domain-containing protein	NA	NA	NA	NA
WP_000513317.1\|268345_268636_+	hypothetical protein	NA	NA	NA	NA
WP_000227712.1\|269886_270390_+	hypothetical protein	NA	NA	NA	NA
WP_001298174.1\|270483_270972_+	integrating conjugative element protein	NA	NA	NA	NA
WP_001118042.1\|271242_272013_-	2-oxoglutaramate amidase	NA	NA	NA	NA
WP_000532690.1\|272166_272640_+	C-lysozyme inhibitor	NA	NA	NA	NA
WP_000973131.1\|272682_275127_-	acyl-CoA dehydrogenase FadE	NA	NA	NA	NA
WP_000284050.1\|275366_275945_+	D-sedoheptulose 7-phosphate isomerase	A0A067XQR2	Caulobacter_phage	1.1e-14	32.0
WP_001298195.1\|276149_276917_+	class II glutamine amidotransferase	NA	NA	NA	NA
WP_001225679.1\|276887_277628_-	murein L,D-transpeptidase	NA	NA	NA	NA
WP_000093935.1\|277939_278689_+	C40 family peptidase	A0A1V0DZX6	Clostridioides_phage	1.5e-19	37.7
WP_000006241.1\|278864_279362_+\|transposase	REP-associated tyrosine transposase RayT	NA	NA	NA	NA
WP_011579064.1\|279444_279654_-	hypothetical protein	NA	NA	NA	NA
WP_001298188.1\|279681_281421_-	flagellar biosynthesis protein FlhA	NA	NA	NA	NA
WP_000207578.1\|281365_282151_+	putative lateral flagellar export/assembly protein LafU	NA	NA	NA	NA
WP_001226168.1\|282221_283277_+	DNA polymerase IV	NA	NA	NA	NA
WP_000554758.1\|283328_283622_+	type I toxin-antitoxin system antitoxin YafN	NA	NA	NA	NA
WP_001263500.1\|283624_284023_+	type II toxin-antitoxin system mRNA interferase toxin YafO	NA	NA	NA	NA
WP_001059895.1\|284032_284485_+	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_000521561.1\|284674_285814_+	RNA ligase RtcB family protein	A0A222ZMP7	Mycobacterium_phage	7.7e-31	31.8
WP_000602124.1\|285810_286425_+	peptide chain release factor H	NA	NA	NA	NA
WP_001292999.1\|286481_287939_-	cytosol nonspecific dipeptidase	NA	NA	NA	NA
WP_001291991.1\|288199_288658_+	xanthine phosphoribosyltransferase	NA	NA	NA	NA
WP_000189578.1\|288749_289994_+	esterase FrsA	NA	NA	NA	NA
WP_000174703.1\|290051_290453_+	sigma factor-binding protein Crl	NA	NA	NA	NA
WP_000749895.1\|290491_291547_-	phosphoporin PhoE	Q1MVN1	Enterobacteria_phage	2.2e-117	60.6
WP_001285288.1\|291835_292939_+	glutamate 5-kinase	A0A1X9I5D0	Streptococcus_phage	1.1e-61	40.4
WP_000893298.1\|292950_294204_+	glutamate-5-semialdehyde dehydrogenase	A0A1X9I5D4	Streptococcus_phage	5.8e-96	47.5
WP_011579066.1\|294408_295569_-\|integrase	site-specific integrase	K7P7R5	Enterobacteria_phage	1.0e-227	99.5
WP_001281200.1\|295882_296227_-	hypothetical protein	A0A0P0ZB93	Stx2-converting_phage	5.9e-59	99.1
WP_001298025.1\|296524_297547_+\|transposase	IS21-like element IS100 family transposase	A0A2L1IVA1	Escherichia_phage	6.0e-200	99.4
WP_001297096.1\|297546_298326_+	AAA family ATPase	A0A2L1IVB6	Escherichia_phage	4.5e-139	99.6
304280:304295	attR	NA	NA	NA	NA

DBSCAN-SWA_2

1183562 : 1228763

Enterobacteria_phage(50.94%)

portal,transposase,terminase,tRNA,tail,head,lysis,capsid

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_001298466.1\|1183562_1184669_-\|tRNA	tRNA 2-thiouridine(34) synthase MnmA	NA	NA	NA	NA
WP_000476093.1\|1184722_1185184_-	phosphatase NudJ	NA	NA	NA	NA
WP_001248678.1\|1185193_1185847_-	23S rRNA pseudouridine(2457) synthase RluE	NA	NA	NA	NA
WP_000444487.1\|1186018_1187269_+	NADP-dependent isocitrate dehydrogenase	Q77Z09	Phage_21	3.8e-23	100.0
WP_001297096.1\|1188066_1188846_-	AAA family ATPase	A0A2L1IVB6	Escherichia_phage	4.5e-139	99.6
WP_001298025.1\|1188845_1189868_-\|transposase	IS21-like element IS100 family transposase	A0A2L1IVA1	Escherichia_phage	6.0e-200	99.4
WP_000088653.1\|1190473_1190710_-	excisionase	NA	NA	NA	NA
WP_000488406.1\|1190849_1191089_-	DUF4222 domain-containing protein	M1FPC8	Enterobacteria_phage	3.9e-38	94.9
WP_000763364.1\|1191136_1191355_-	TraR/DksA family transcriptional regulator	M1FQT7	Enterobacteria_phage	1.8e-34	95.8
WP_000188880.1\|1191453_1191669_-	hypothetical protein	A0A1I9LJM7	Stx_converting_phage	2.9e-32	98.6
WP_000548537.1\|1191745_1191937_-	DUF1382 family protein	A0A0P0ZC67	Stx2-converting_phage	2.1e-26	98.4
WP_000682300.1\|1191909_1192092_-	DUF1317 domain-containing protein	A0A0N7CHV0	Escherichia_phage	1.3e-28	98.3
WP_000186833.1\|1192088_1192769_-	YqaJ viral recombinase family protein	B6DZ61	Enterobacteria_phage	5.1e-131	98.2
WP_011579115.1\|1192765_1193551_-	phage recombination protein Bet	A0A1I9LJN0	Stx_converting_phage	3.1e-148	99.6
WP_000995491.1\|1193556_1193853_-	host-nuclease inhibitor protein Gam	A0A1I9LJN1	Stx_converting_phage	3.6e-49	99.0
WP_000233576.1\|1193927_1194134_-	phage encoded cell division inhibitor protein	K7P6H3	Enterobacteria_phage	3.2e-28	85.3
WP_000866321.1\|1194609_1194987_-	ASCH domain-containing protein	Q6SE87	Lactobacillus_prophage	1.3e-30	49.2
WP_000380252.1\|1194964_1196026_-	hypothetical protein	Q6SE88	Lactobacillus_prophage	2.9e-64	42.0
WP_001337214.1\|1196106_1196799_-	helix-turn-helix transcriptional regulator	Q76H56	Enterobacteria_phage	1.5e-109	86.1
WP_000184665.1\|1196909_1197137_+	helix-turn-helix domain-containing protein	Q76H55	Enterobacteria_phage	3.8e-22	69.0
WP_001182882.1\|1197167_1197707_+	toxin YdaT domain-containing protein	M9NZI6	Enterobacteria_phage	8.9e-62	66.7
WP_000147913.1\|1197703_1198723_+	replication protein	A0A0M5M7Y1	Salmonella_phage	6.1e-112	64.7
WP_000788796.1\|1198719_1199433_+	hypothetical protein	G8C7U6	Escherichia_phage	9.8e-109	83.4
WP_000608370.1\|1199511_1199940_-	hypothetical protein	NA	NA	NA	NA
WP_000182282.1\|1199936_1200314_-	hypothetical protein	NA	NA	NA	NA
WP_001053041.1\|1200581_1201037_+	DNA base-flipping protein YbcN	I6PD71	Cronobacter_phage	7.0e-60	66.2
WP_000224917.1\|1201036_1201207_+	hypothetical protein	K7P7K0	Enterobacteria_phage	2.0e-12	67.9
WP_000774485.1\|1201199_1201490_+	DUF1364 domain-containing protein	K7PGZ6	Enterobacteria_phage	9.6e-47	92.7
WP_001099712.1\|1201486_1201849_+	crossover junction endodeoxyribonuclease RusA	K7PM48	Enterobacteria_phage	4.3e-60	96.5
WP_000971056.1\|1201845_1201986_+	YlcG family protein	K7PHH3	Enterobacteria_phage	1.1e-08	69.8
WP_001204776.1\|1202071_1202455_+	antitermination protein QuuD	A0A088CD47	Shigella_phage	1.5e-55	83.3
WP_000737271.1\|1202643_1203726_-	porin OmpC	Q1MVN1	Enterobacteria_phage	1.6e-166	80.1
WP_000839596.1\|1204314_1204530_+\|lysis	phage lysis protein EssD	A5LH82	Enterobacteria_phage	9.0e-34	100.0
WP_001135283.1\|1204529_1205027_+	lysozyme RrrD	M1FJA0	Enterobacteria_phage	2.1e-89	96.4
WP_001228695.1\|1205243_1205426_+\|lysis	prophage lysis lipoprotein RzoD	K7PHU6	Enterobacteria_phage	2.9e-17	98.3
WP_001298464.1\|1205516_1205810_-	increased serum survival lipoprotein Iss	K7PL54	Enterobacteria_phage	7.0e-45	92.8
WP_000830178.1\|1206290_1206617_+	TonB family protein	H6WZK5	Escherichia_phage	3.7e-39	72.2
WP_000881607.1\|1206823_1207006_+	hypothetical protein	NA	NA	NA	NA
WP_000867508.1\|1207568_1208114_+\|terminase	terminase small subunit	A0A0K2FIG2	Enterobacteria_phage	1.2e-79	82.9
WP_001027310.1\|1208088_1210014_+\|terminase	phage terminase large subunit family protein	A0A0K2FJ14	Enterobacteria_phage	0.0e+00	99.5
WP_000198149.1\|1210010_1210217_+	gpW family protein	A0A2R9YJL2	Escherichia_phage	5.8e-30	100.0
WP_011579118.1\|1210213_1211815_+\|portal	phage portal protein	A0A0K2FJC0	Enterobacteria_phage	1.3e-310	99.4
WP_000123275.1\|1211795_1213115_+	S49 family peptidase	A0A2I6TC87	Escherichia_phage	1.0e-231	97.9
WP_001298472.1\|1213124_1213457_+\|head	head decoration protein	A0A2R9YJN3	Escherichia_phage	1.4e-54	98.2
WP_000063225.1\|1213512_1214538_+\|capsid	major capsid protein	C6ZCY2	Enterobacteria_phage	6.9e-188	97.1
WP_000158869.1\|1214579_1214975_+	DNA-packaging protein FI	A0A2R9YJP4	Escherichia_phage	5.7e-58	95.5
WP_000752960.1\|1214986_1215340_+\|head,tail	head-tail joining protein	A0A2R9YJJ5	Escherichia_phage	7.6e-62	99.1
WP_000985116.1\|1215351_1215930_+\|tail	phage tail protein	A0A2R9YJK4	Escherichia_phage	7.8e-80	97.9
WP_000683140.1\|1215926_1216322_+\|tail	tail protein	A0A2R9YJI2	Escherichia_phage	4.2e-69	97.7
WP_001298481.1\|1216329_1217070_+\|tail	phage tail protein	A0A0K2FJ05	Enterobacteria_phage	2.6e-128	96.7
WP_000479168.1\|1217085_1217508_+\|tail	phage minor tail protein G	A0A0K2FIQ8	Enterobacteria_phage	1.2e-69	95.0
WP_000459484.1\|1217489_1217924_+\|tail	phage tail assembly protein T	A0A0K2FJB3	Enterobacteria_phage	5.0e-63	97.5
WP_000840199.1\|1217916_1220484_+\|tail	phage tail tape measure protein	A0A2R9YJM8	Escherichia_phage	0.0e+00	93.5
WP_000847330.1\|1220480_1220810_+\|tail	phage tail protein	A0A2R9YJM0	Escherichia_phage	1.6e-58	100.0
WP_001152619.1\|1220809_1221508_+\|tail	phage minor tail protein L	A0A0K2FJ01	Enterobacteria_phage	7.3e-133	99.1
WP_001519691.1\|1221513_1222257_+\|tail	phage tail protein	K7PLW1	Enterobacteria_phage	2.0e-149	97.6
WP_000090917.1\|1222193_1222826_+\|tail	tail assembly protein	A0A2R9YJH6	Escherichia_phage	5.9e-97	100.0
WP_000515728.1\|1222886_1226369_+	host specificity protein J	A0A291AWT4	Escherichia_phage	0.0e+00	90.2
WP_001519693.1\|1226427_1228488_+\|tail	prophage tail fiber N-terminal domain-containing protein	A0A0E3M194	Enterobacteria_phage	3.3e-125	53.5
WP_000654175.1\|1228484_1228763_+	hypothetical protein	A0A0E3JSQ1	Enterobacteria_phage	9.9e-25	57.6

DBSCAN-SWA_3

2849945 : 2857085

Escherichia_phage(83.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000106696.1\|2849945_2852507_+	DNA mismatch repair protein MutS	E3T5Q7	Cafeteria_roenbergensis_virus	1.6e-31	20.8
WP_001141304.1\|2852612_2853269_+	protein-serine/threonine phosphatase	A0A077SLQ6	Escherichia_phage	8.6e-51	46.6
WP_024174328.1\|2853319_2854087_-	DeoR/GlpR transcriptional regulator	A0A077SK06	Escherichia_phage	1.6e-69	56.3
WP_000847997.1\|2854282_2855191_+	NAD(P)-dependent oxidoreductase	A0A077SLF7	Escherichia_phage	1.5e-117	76.5
WP_000590411.1\|2855187_2856450_+	3-oxo-tetronate kinase	A0A077SLJ7	Escherichia_phage	2.2e-135	61.4
WP_001279002.1\|2856446_2857085_+	aldolase	A0A077SK32	Escherichia_phage	3.7e-83	75.0

DBSCAN-SWA_4

3948172 : 4014815

Escherichia_phage(26.67%)

transposase,integrase

attL 3943565:3943579|attR 4020149:4020163

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
3943565:3943579	attL	NA	NA	NA	NA
WP_001218923.1\|3948172_3949354_+\|integrase	tyrosine-type recombinase/integrase	Q7M297	Enterobacteria_phage	7.4e-162	69.2
WP_000869865.1\|3949967_3950912_+	DNA cytosine methyltransferase	A7XXH6	Thermus_virus	1.3e-60	39.9
WP_000869867.1\|3950908_3951841_+	DNA cytosine methyltransferase	A7XXH6	Thermus_virus	5.9e-53	38.7
WP_000286814.1\|3951904_3953161_+	HNH endonuclease	NA	NA	NA	NA
WP_011579236.1\|3954834_3955068_+	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_001297096.1\|3955800_3956580_-	AAA family ATPase	A0A2L1IVB6	Escherichia_phage	4.5e-139	99.6
WP_011579238.1\|3956579_3957602_-\|transposase	IS21-like element IS100 family transposase	A0A2L1IVA1	Escherichia_phage	2.3e-199	99.1
WP_021554776.1\|3958380_3958881_-	HTH-type transcriptional regulator PapX	NA	NA	NA	NA
WP_000935974.1\|3959406_3959613_-	hypothetical protein	NA	NA	NA	NA
WP_000821052.1\|3960708_3961788_-	type 1 fimbrial protein	NA	NA	NA	NA
WP_011579244.1\|3961784_3964319_-	fimbrial biogenesis outer membrane usher protein	NA	NA	NA	NA
WP_000943621.1\|3964326_3965052_-	fimbria/pilus periplasmic chaperone	NA	NA	NA	NA
WP_000695740.1\|3965109_3965661_-	fimbrial protein F17	NA	NA	NA	NA
WP_001519150.1\|3966232_3966631_-	DoxX family protein	NA	NA	NA	NA
WP_001131383.1\|3966657_3967875_-	alpha-hydroxy-acid oxidizing protein	NA	NA	NA	NA
WP_000680149.1\|3967925_3968474_-	nuclear transport factor 2 family protein	NA	NA	NA	NA
WP_001111227.1\|3968643_3969285_+	TetR/AcrR family transcriptional regulator	NA	NA	NA	NA
WP_011579253.1\|3970732_3972415_+	DUF3987 domain-containing protein	NA	NA	NA	NA
WP_001126807.1\|3973971_3974538_+	inovirus-type Gp2 protein	NA	NA	NA	NA
WP_000991574.1\|3974784_3975357_+	hypothetical protein	NA	NA	NA	NA
WP_000958492.1\|3975425_3975659_+	AlpA family transcriptional regulator	NA	NA	NA	NA
WP_000832724.1\|3975655_3975814_+	hypothetical protein	NA	NA	NA	NA
WP_114311086.1\|3977410_3978579_-\|transposase	IS3 family transposase	Q716C2	Shigella_phage	1.0e-171	91.8
WP_021556221.1\|3979616_3980387_-	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_000738260.1\|3980638_3981229_+	type 1 fimbrial protein	NA	NA	NA	NA
WP_001270429.1\|3981284_3981986_+	molecular chaperone	NA	NA	NA	NA
WP_000989515.1\|3981966_3982398_+	molecular chaperone	NA	NA	NA	NA
WP_001046493.1\|3982470_3984978_+	fimbrial biogenesis outer membrane usher protein	NA	NA	NA	NA
WP_011579264.1\|3984965_3985418_+	molecular chaperone	NA	NA	NA	NA
WP_011579265.1\|3985407_3985956_+	type 1 fimbrial protein	NA	NA	NA	NA
WP_000910077.1\|3985975_3987241_+	hypothetical protein	NA	NA	NA	NA
WP_021538799.1\|3987308_3987473_-	hypothetical protein	NA	NA	NA	NA
WP_011579266.1\|3987474_3988671_-\|transposase	IS110 family transposase	NA	NA	NA	NA
WP_024174340.1\|3988996_3989401_-	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_011579270.1\|3989621_3990458_+	ABC transporter ATP-binding protein	NA	NA	NA	NA
WP_000979296.1\|3990454_3991309_+	metal ABC transporter permease	NA	NA	NA	NA
WP_000830501.1\|3991352_3992231_+	metal ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_021538796.1\|3992553_3992775_-	hypothetical protein	NA	NA	NA	NA
WP_001534651.1\|3993045_3993558_+	alpha-hemolysin-activating lysine-acyltransferase HlyC	NA	NA	NA	NA
WP_001142372.1\|3993569_3996644_+	RTX toxin hemolysin HlyA	NA	NA	NA	NA
WP_000376544.1\|3996714_3998838_+	type I secretion system permease/ATPase	W8CYL7	Bacillus_phage	8.4e-47	29.7
WP_000860470.1\|3998856_4000293_+	alpha-hemolysin T1SS ABC transporter subunit HlyD	NA	NA	NA	NA
WP_000273361.1\|4000590_4001511_+	urea transporter	NA	NA	NA	NA
WP_000199856.1\|4001752_4002985_+	phosphoadenosine phosphosulfate reductase	A0A068F1U8	Mycobacterium_phage	8.3e-63	34.0
WP_000502866.1\|4002969_4003614_+	ParB N-terminal domain-containing protein	A0A0F7L444	uncultured_marine_virus	3.7e-54	51.0
WP_000659219.1\|4005142_4005958_+	AraC family transcriptional regulator	NA	NA	NA	NA
WP_021538786.1\|4006488_4006659_+	IS66 family insertion sequence element accessory protein TnpB	A0A0P0ZDM8	Stx2-converting_phage	1.8e-13	58.9
WP_011579276.1\|4008031_4009264_-	group II intron reverse transcriptase/maturase	A0A0U4J920	Pseudomonas_phage	1.0e-28	32.1
WP_001298025.1\|4011115_4012138_+\|transposase	IS21-like element IS100 family transposase	A0A2L1IVA1	Escherichia_phage	6.0e-200	99.4
WP_001297096.1\|4012137_4012917_+	AAA family ATPase	A0A2L1IVB6	Escherichia_phage	4.5e-139	99.6
WP_000612581.1\|4014159_4014429_-	IS66 family insertion sequence element accessory protein TnpB	A0A0P0ZBY2	Stx2-converting_phage	3.4e-46	98.9
WP_001282150.1\|4014425_4014815_-\|transposase	transposase	B6DZU5	Stx2-converting_phage	1.7e-67	98.4
4020149:4020163	attR	NA	NA	NA	NA

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. NC_008253

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

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Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection