CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NC_007801	Jannaschia sp. CCS1 plasmid p1, complete sequence	0 crisprs	NA	0	0	1	0
NC_007802	Jannaschia sp. CCS1, complete sequence	1 crisprs	DEDDh,csa3,WYL,cas3	0	0	3	0

Results visualization

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CRISPR-Cas detection and classification

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

74398 : 84913

Bacillus_phage(16.67%)

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_166486314.1\|74398_76144_-	ATP-binding cassette domain-containing protein	W8CYL7	Bacillus_phage	4.8e-40	27.3
WP_011453121.1\|76415_77585_+	glycosyltransferase	E5EQR6	Micromonas_sp._RCC1109_virus	1.6e-10	30.1
WP_011453122.1\|77870_78908_+	GDP-mannose 4,6-dehydratase	M1IBC3	Acanthocystis_turfacea_Chlorella_virus	3.0e-98	52.2
WP_044007935.1\|78922_79819_+	NAD-dependent epimerase/dehydratase family protein	J7Q7J8	Aeropyrum_coil-shaped_virus	4.4e-13	27.9
WP_011453124.1\|79994_81224_+	FkbM family methyltransferase	A0A1V0SAF0	Catovirus	1.6e-10	27.3
WP_011453125.1\|81223_84913_+	glycosyltransferase	Q684B1	Sulfolobus_virus	6.6e-07	31.2

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

2. NC_007802

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CRISPR-Cas detection and classification

Crispr_ID: NC_007802_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_007802_1

2920357-2920445

Orphan

Consensus_repeat	Method
GCTACTTGAGGCCGGGATATCATT	CRISPRCasFinder

1 spacers

The CRISPR arrays of NC_007802_1

>merge|NC_007802|1|2920357-2920445|CRISPRCasFinder
GCTACTTGAGGCCGGGATATCATTCCTTTTTGGCCTACCGCCCTTTTGGGCCTACCGCCCTTTGGGCTACTTGAGGCCAGGATATCATT

>NC_007802|1|1|2920357-2920445|CRISPRCasFinder
GCTACTTGAGGCCGGGATATCATT	CCTTTTTGGCCTACCGCCCTTTTGGGCCTACCGCCCTTTGG
GCTACTTGAGGCCAGGATATCATT

Protein	Signature genes	Signature genes Name	Protein_function
NC_007802.1\|WP_011456029.1\|2928392_2929583_+\|3-hydroxybenzoate-6-monooxygenase	unknown	unknown	gnl\|CDD\|181262
NC_007802.1\|WP_011456022.1\|2920684_2921716_+\|LacI-family-DNA-binding-transcriptional-regulator	unknown	unknown	gnl\|CDD\|224525
NC_007802.1\|WP_011456027.1\|2926036_2926804_+\|L-iditol-2-dehydrogenase	unknown	unknown	gnl\|CDD\|235925
NC_007802.1\|WP_166486268.1\|2914395_2915013_-\|recombinase-family-protein	unknown	unknown	gnl\|CDD\|214861
NC_007802.1\|WP_044006874.1\|2926829_2928317_+\|mannitol-dehydrogenase-family-protein	unknown	unknown	gnl\|CDD\|223324
NC_007802.1\|WP_011456016.1\|2913869_2914403_-\|hypothetical-protein	unknown	unknown	unknown
NC_007802.1\|WP_011456023.1\|2921836_2923156_+\|sugar-ABC-transporter-substrate-binding-protein	unknown	unknown	gnl\|CDD\|270303
NC_007802.1\|WP_011456026.1\|2925035_2926040_+\|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|226359
NC_007802.1\|WP_166486148.1\|2915651_2917997_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|273716
NC_007802.1\|WP_011456030.1\|2929583_2930276_+\|fumarylacetoacetate-hydrolase-family-protein	unknown	unknown	gnl\|CDD\|223257
NC_007802.1\|WP_166486269.1\|2930284_2931346_+\|cupin-domain-containing-protein	unknown	unknown	gnl\|CDD\|225969
NC_007802.1\|WP_044007619.1\|2913432_2913873_+\|hypothetical-protein	unknown	unknown	unknown
NC_007802.1\|WP_011456013.1\|2911476_2912190_-\|hypothetical-protein	unknown	unknown	unknown
NC_007802.1\|WP_011456025.1\|2924158_2924989_+\|carbohydrate-ABC-transporter-permease	unknown	unknown	gnl\|CDD\|223472
NC_007802.1\|WP_011456024.1\|2923281_2924148_+\|sugar-ABC-transporter-permease	unknown	unknown	gnl\|CDD\|224096
NC_007802.1\|WP_044006870.1\|2918125_2918323_-\|AlpA-family-phage-regulatory-protein	unknown	unknown	gnl\|CDD\|225848
NC_007802.1\|WP_044006869.1\|2911216_2911477_-\|hypothetical-protein	unknown	unknown	unknown
NC_007802.1\|WP_011456021.1\|2918944_2920120_-\|site-specific-integrase	unknown	unknown	gnl\|CDD\|271182
NC_007802.1\|WP_044006872.1\|2918423_2918954_-\|hypothetical-protein	unknown	unknown	unknown
NC_007802.1\|WP_011456014.1\|2912399_2913338_+\|hypothetical-protein	unknown	unknown	unknown

Protein	Function_ID	Function_description	E-value
NC_007802.1\|WP_011456029.1\|2928392_2929583_+\|3-hydroxybenzoate-6-monooxygenase	gnl\|CDD\|181262	PRK08163, PRK08163, 3-hydroxybenzoate 6-monooxygenase.	0
NC_007802.1\|WP_011456022.1\|2920684_2921716_+\|LacI-family-DNA-binding-transcriptional-regulator	gnl\|CDD\|224525	COG1609, PurR, Transcriptional regulators [Transcription].	5.66539e-69
NC_007802.1\|WP_011456027.1\|2926036_2926804_+\|L-iditol-2-dehydrogenase	gnl\|CDD\|235925	PRK07067, PRK07067, L-iditol 2-dehydrogenase.	1.05567e-156
NC_007802.1\|WP_166486268.1\|2914395_2915013_-\|recombinase-family-protein	gnl\|CDD\|214861	smart00857, Resolvase, Resolvase, N terminal domain. The N-terminal domain of the resolvase family contains the active site and the dimer interface. The extended arm at the C-terminus of this domain connects to the C-terminal helix-turn-helix domain of resolvase.	6.93221e-46
NC_007802.1\|WP_044006874.1\|2926829_2928317_+\|mannitol-dehydrogenase-family-protein	gnl\|CDD\|223324	COG0246, MtlD, Mannitol-1-phosphate/altronate dehydrogenases [Carbohydrate transport and metabolism].	1.84556e-157
NC_007802.1\|WP_011456026.1\|2925035_2926040_+\|ABC-transporter-ATP-binding-protein	gnl\|CDD\|226359	COG3839, MalK, ABC-type sugar transport systems, ATPase components [Carbohydrate transport and metabolism].	2.54308e-173
NC_007802.1\|WP_166486148.1\|2915651_2917997_-\|hypothetical-protein	gnl\|CDD\|273716	TIGR01613, putative_primase, phage/plasmid primase, P4 family, C-terminal domain. This model represents a clade within a larger family of proteins from viruses of bacteria and animals. Members of this family are found in phage and plasmids of bacteria and archaea only. The model describes a domain of about 300 residues, found generally toward the protein C-terminus. [DNA metabolism, DNA replication, recombination, and repair, Mobile and extrachromosomal element functions, Prophage functions].	0.0005909
NC_007802.1\|WP_011456030.1\|2929583_2930276_+\|fumarylacetoacetate-hydrolase-family-protein	gnl\|CDD\|223257	COG0179, MhpD, 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway) [Secondary metabolites biosynthesis, transport, and catabolism].	5.67138e-86
NC_007802.1\|WP_166486269.1\|2930284_2931346_+\|cupin-domain-containing-protein	gnl\|CDD\|225969	COG3435, COG3435, Gentisate 1,2-dioxygenase [Secondary metabolites biosynthesis, transport, and catabolism].	9.30804e-127
NC_007802.1\|WP_011456023.1\|2921836_2923156_+\|sugar-ABC-transporter-substrate-binding-protein	gnl\|CDD\|270303	cd13585, PBP2_TMBP_like, The periplasmic-binding component of ABC transport systems specific for trehalose/maltose and similar oligosaccharides; possess type 2 periplasmic binding fold. This family includes the periplasmic trehalose/maltose-binding component of an ABC transport system and related proteins from archaea and bacteria. Members of this group belong to the type 2 periplasmic-binding fold superfamily. PBP2 is comprised of two globular subdomains connected by a flexible hinge and bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap. The majority of PBP2 proteins function in the uptake of small soluble substrates in eubacteria and archaea. After binding their specific ligand with high affinity, they can interact with a cognate membrane transport complex comprised of two integral membrane domains and two cytoplasmically located ATPase domains. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis.	8.78593e-64
NC_007802.1\|WP_011456025.1\|2924158_2924989_+\|carbohydrate-ABC-transporter-permease	gnl\|CDD\|223472	COG0395, UgpE, ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism].	1.50287e-68
NC_007802.1\|WP_011456024.1\|2923281_2924148_+\|sugar-ABC-transporter-permease	gnl\|CDD\|224096	COG1175, UgpA, ABC-type sugar transport systems, permease components [Carbohydrate transport and metabolism].	7.50504e-61
NC_007802.1\|WP_044006870.1\|2918125_2918323_-\|AlpA-family-phage-regulatory-protein	gnl\|CDD\|225848	COG3311, AlpA, Predicted transcriptional regulator [Transcription].	1.04107e-14
NC_007802.1\|WP_011456021.1\|2918944_2920120_-\|site-specific-integrase	gnl\|CDD\|271182	cd00801, INT_P4_C, Bacteriophage P4 integrase, C-terminal catalytic domain. P4-like integrases are found in temperate bacteriophages, integrative plasmids, pathogenicity and symbiosis islands, and other mobile genetic elements. The P4 integrase mediates integrative and excisive site-specific recombination between two sites, called attachment sites, located on the phage genome and the bacterial chromosome. The phage attachment site is often found adjacent to the integrase gene, while the host attachment sites are typically situated near tRNA genes. This family belongs to the superfamily of DNA breaking-rejoining enzymes, which share the same fold in their catalytic domain and the overall reaction mechanism. The catalytic domain contains six conserved active site residues. Their overall reaction mechanism involves cleavage of a single strand of a DNA duplex by nucleophilic attack of a conserved tyrosine to give a 3' phosphotyrosyl protein-DNA adduct. In the second rejoining step, a terminal 5' hydroxyl attacks the covalent adduct to release the enzyme and generate duplex DNA.	3.96879e-40

>NC_007802.1|WP_011456021.1|2918944_2920120_-|site-specific-integrase
MKKKLTEMAVSKIAPEAGRRLEVFDTLTPGLALRVTERGKKSWSVMYRVAGRGREGIRGPLRRMTLGAYPLIDLKAARERARAAIDLADRGEDPADKRKDEMRKKGERVFEVICARFIELHAKAHTVKWRDTERLLDTYAVPAWRGKPIDQIDRAAAHELLDDIAMEHGTGAAREVRKHITKLFNWSVDRGLLAASPVAGMRRPELGYTPRERVLTMDELRAVWAAAGKMGYPFGPMVRLLILTAQRRAEVANLERGWLLPDHQAFEVPASHYKTDRPQVVPLSAPALALVEGLPKWNSGDFMLSTTAGKRPVSGFSKAKARLDKLSEVEGWTLHDLRRSAATHMARLGVAQEHIERVLGHAIEGVAGTYNRYSYLPEKRAALDAWGQEWN
>NC_007802.1|WP_044006872.1|2918423_2918954_-|hypothetical-protein
MELTGEELARVREAYDRVAQMAVWEGYADDKARGERPALVRLMKAWNKLDIEERAAVSLELAQMVSPDADPHDLDVGLAATRAAEYGRGRAGAKVRVPGFREAVREAAQVWIDRGNEWSRGNIHRDTNRYEPYPMLAFVVDAVTRALPSDAIARATLGNPPSPEEVMAAVDSQLRP
>NC_007802.1|WP_044006870.1|2918125_2918323_-|AlpA-family-phage-regulatory-protein
MPETDTLLTIEEVAVRTRLSKPTIYKLIRQGDFPRQLRLCANKVAWLEREVSDWVVARAEARTTG
>NC_007802.1|WP_166486148.1|2915651_2917997_-|hypothetical-protein
MLPDPDASVAFLEGWRSGGPWVLTAIEVDPPKGRDPRTPTVALSAPEKARQWITDHSGGGWNLYFTVNVTRGPVGKKPKKADMAAATGLHVDVDPRPGEDIDRERARAEKVLRGYGPQPTVIIDSGGGFQGFWKFDEELHLTGEPEDETRHLPVEERNLKIEAVLQGDSCHNVDRVMRLPGTVNWPNDKKRKKGRKPALAQVVDVDWSRTYAPGDFERSPMFAKSASSGTAQVTLPKDLPELLGLESLPTAVSDRTKMLITVGDDPDDPMRYASRSEVLFAVLCELVRAEVADDVIAAVILDEDYGISGHINDQADPRRYARRQIQRARDEAVDPALRELNDQFTVLENEGGKCRILEFVEMPTGVKGKTRSVVTLQSFEDFRNRFLNRSVVVGKDKEGNDVKMALGKWWLQNAARRQFHSLTFRPRDGEEVGTGATRQLNLWQGFTVRPTPGDWSLMRAHIRDVLASGDEASDSYIIRWMAWTLQNPDEPAEVALTFRGEPGTGKGVFGRTMAQLFGQHGLHTGGSEMITGRFNKHFRDCCLLFADEVVWDGDRKAEAKVKTFLTEPTLMIEGKGVDAVTWPNMLHVIISSNSEWVVPAGPFERRYAVFDVAATQRQKRGYFAPLFAELESGGLAAMLCDLLAMDLGRWHPREDVPKTDALNDQKSRGLDPVHAAVLDMLREGALPSDISADARGTDARPFVATDELAAFVQRQSRAVVTSVVVSKLLDKIGGEKNRKRRPSGYVLPLLAEARAAWDAQPDLPTQIWDDAADWAGGGEPW
>NC_007802.1|WP_166486268.1|2914395_2915013_-|recombinase-family-protein
MDYPKTPQRRAAIYARVSTGEQTPENQLIRLREVAERAGWAVVCEYVETASGTKRARPALDAMVKDAARRRFDVVMAWDVSRLGRSLRDLVDLFEMLRSVGCDLFLEQQALDTSTPAGRALLQMSGVFAEFERAMIVERTKAGMARARANGKQIGRAPAPEALKDAIRALRADGIGMDRIARQLKCGKGLSQRVCQEFDKEMAHG
>NC_007802.1|WP_011456016.1|2913869_2914403_-|hypothetical-protein
MDENRFDAVARRVSDGTPGGPAYRVGRRGLKIVEELAARGVAEATMAKALRMGKDAFRAAKRRDPAVQEAIDRGRAVEHDKLVGVLHDLAMEGQYVPAMFLLKARHGYREGEQFEANVNLSIDTGGVLVVPNKMSMEEFLEAQRQAGTYDSPIRPDAVKRIPGEPEVVVDPETRRGD
>NC_007802.1|WP_044007619.1|2913432_2913873_+|hypothetical-protein
MVANNPNAVNTVVTIFSILAGFLIAVITFIAEPTLQQARTWDELQRMKETVRRKLIRQKLLFFLYLLTLGIALAMFLTPPTMLEPLKWLQTAFLGLATFVFLASFSLPGSLMKIQMERYEAALEDSRPKVVTDAKKAAEQAKKRKP
>NC_007802.1|WP_011456014.1|2912399_2913338_+|hypothetical-protein
MARQTKTLEYRRARFLDDGQNLEALVRQAWGQFGTQAERTITFSDDRSSCGLRARDCNANGFAVHCGRYTDGQGVGTIPTVPAPEVEVGERPPEPGENFLNSDLMALISGNHVICMNCGRNAGSLRIYLQQLFRKAGMPDESRQFELVRIGSPDKLAIIEAVGVKSIDLEVDISEATAFEVVEGDGGGGIWQSIKQNFGNALAAVTARDESVEQLRTAERGTMKVSINVPKGDLDAAKHGLDDFAEEVVEDEESDAFTIHLRDGRTTIKPNEVSVRKQVKLETAANSVSVFQAWDAMETYMGELNENGQIEA
>NC_007802.1|WP_011456013.1|2911476_2912190_-|hypothetical-protein
MADPAPSLPLDIPDKPILSTAEVVSLAEVAAKRAEKFGTLIDTLDAGVAKRAADAAESFSRAGFQPKDQQTAADKAAAIARREVVTNSSDTRWAHLKELSAASDSLATTAQLWASPVTVLARAGLGTPERSAYQQQLDGSGVVDLKNVALLAVATNNKALGAAIVSIIDRMPARSRPFSAQDLADKLVGEETRSVQAAIAAVKLAAQRAINRNREYEAGRVRPMDRVKLALNKKDAN
>NC_007802.1|WP_044006869.1|2911216_2911477_-|hypothetical-protein
MPLYLVTRPKGAAHLKNPSAIHAALVDAADGPAAVLAADALTPHLNTPFAGFDTTQVAATVAGGFVPCVFQGDALGATYTGPGRGA
>NC_007802.1|WP_011456022.1|2920684_2921716_+|LacI-family-DNA-binding-transcriptional-regulator
MADQQIRNMEDFAAVSGISRPTVSKYFNDPQSVRATTRARIEQALDRYDYRPNIYAVNQNRRLTKNVGIMVPYLADPFFAEIARNIEMMVIEAGFRPILLSSHGSPEQEAENMESLRVLKPAGVLMAPLGRASDRSAVEKFCRDVPTILFDSNLDGMGEAFIGSDNVSFVEQTVAYISQSGSPPCFFEMKNPANPNANKRRNAYIAAMETRGLEPRVISIDGDGWAFEEIGRIGAHDVLQAGQLPTNTVICSNDRLAIGFLAACYERGLRVGSGPDCALRVASHDDHPFSRFTCPALTTAAHDYDSVSKSSVDTLFQLIENGARLPQRHETLFPAKLIIRASA
>NC_007802.1|WP_011456023.1|2921836_2923156_+|sugar-ABC-transporter-substrate-binding-protein
MSLKRALSATTALAICAAGTAAFADGHSATITIATVNNGDMVRMQGYTDQFTEETGIAVEWVTLEENVLRQRVTTDITTNGGQFDIMTIGMYETPIWGSNGWLVPLDGLSDDYNVGDILPAMAGGLSHDGTLYAAPFYGESSMVMYRTDLMEAAGLEMPEAPTWEFIREAAAAMTDRDNDINGICLRGKPGWGEGGAFITAMSNSFGARWFDMEWQAQFDTQPWLDTLTFYQGMMQESGPAGYATNGFTENLNLFNQGLCGMWIDATVAASFVTNPDDSTVADSVGFALAPDNGLGVRSNWLWAWALAIPAGTQQQDEALQFIEWATSTDYIELVAENEGWANVPPGARTSLYENPNYIDVPFAQMTLDSILSADPNNSTVEESPYVGIQFAAIPEFAGIATEVSQEFSAFYAGQQTAEEALANAQAITNEAMEAAGYQ
>NC_007802.1|WP_011456024.1|2923281_2924148_+|sugar-ABC-transporter-permease
MATQHSRSAARIMMAPAVFLLLVWMLVPLCMTLWFSVRDFRPLRGGDNGFVGMENFIRFVSSSSFWPAVMTTLIIVGGVLLISICLGVLLAILLDQPMWGQGVVRILVIAPFFVMPTVSALVWKNMFMDPVNGVFSYIWRFFGADPVVWLSEMPVFSIVMIVSWQWLPFATLILLTAIQSLDSEQLEAAEMDGAGPFSRFGFITLPHLSRAITIVILIQTIFLLAVFAEIFVTTGGAFGTRTLTYLIYQRVLESQNVGLGSAGGVYAIILANIVAIFLMRIVGKNLDK
>NC_007802.1|WP_011456025.1|2924158_2924989_+|carbohydrate-ABC-transporter-permease
MARAVTNQRKALNTAIAWIIGLMIFFPILWTILTSFKTEADAIANPPILFAFDWTLENYREVMERSNYGRFLSNSILIAGGSTILGIIIAVPAAWSMAFVPSRRTKDILLWMLSTKMLPAVGVLYPIYLLCIQLGVLDNRYALVVILMLINLPIIVWMLYTYFKEIPGEILEAARMDGASLKEEILYVLTPMAVPGIASTLLLNFILAWNEAFWTLNLTSVDAAPLTAFIASYSSPEGLFFAKLSAASTMAIAPILILGWFSQKQLVRGLTFGAVK
>NC_007802.1|WP_011456026.1|2925035_2926040_+|ABC-transporter-ATP-binding-protein
MGNITLDKVQKSFGEVEVIPPLDLEINEGEFVVFVGPSGCGKSTLLRLIAGLEDVSGGQIRIDGNDATMTPPAKRGLAMVFQSYALYPHMSVRKNIAFPLRMAGMDQAEQERRIDNAARILNLSDYIDRRPGQLSGGQRQRVAIGRAIVREPAAFLFDEPLSNLDAALRVGMRLEITELHSRLKTTMIYVTHDQVEAMTMADKIVVLRAGHIEQVGSPLTLYNEPKNLFVAGFIGSPKMNQFDGAEAAKHNATTIGIRPEHITASLTEGTWKGRVGVTEQLGSDTFFYVHDTGLADAITVRVNGAFLVRSGDEVYLTPDLEKLHRFDADGLRIA
>NC_007802.1|WP_011456027.1|2926036_2926804_+|L-iditol-2-dehydrogenase
MTRLTGKGALITGAARGIGRAFAERYIAEGARVAIADIDLTRAEATAAEIGAIAVQMDVSCEDSIADGVTAAADALGQIDILINNAAVFTAAPLTEITYKDYADVFDINVGGTLFTMQAVAKHMIDRGIRGKIINMASQAGRRGEPLVAVYCATKAAVISLTQSAGLNLIEHGINVNAIAPGVVDGEHWDGVDAFFARHEGKAPGQKKREVGEAVPYGRMGVAEDLTGMAVFLASDEAEYIVSQTYNVDGGQWMS
>NC_007802.1|WP_044006874.1|2926829_2928317_+|mannitol-dehydrogenase-family-protein
MKDTTPALPLRLDTLEALPHGIERPTYSRADLTPGIMHIGLGNFHRAHQAWYLHRLMQAGEAHDWAIIGAGVRAYDAEMRDRLAKQDYLTTLIELTPTSTSAEVIGPMIDYLPIEDGNGALIAAMTDPAIRIVSLTVTEGGYYIDPATHGFDAAHPDMAHDAAHPDSPHTAFGAIIAALRARRDARAPAFTVQSCDNLQGNGAIVRQTVVGLARLGDADLADWIEANASFPNSMVDCIVPATGPAEIALARSFGIDDVAPVSHENYRQWVIEDAFCHGRPAWEKVGATLTDDVHSFEAMKIRLLNGGHQVIANVGELLSCETIADCMADPDIAAFFRKVEHDGIVPYVQAVPGMTPPAYVELIERRFANSAIRDTTRRVAFDGSSRHTGFILPIVREALAAGGSVDALALVEALWARMCAGTREDGTMIAPNDPFWDDLHATAQAARTRPAAWLEQTHLYGDLADHPAFAEAFTGWLSDIWSNGSRATIHRFIAA
>NC_007802.1|WP_011456029.1|2928392_2929583_+|3-hydroxybenzoate-6-monooxygenase
MTQPILIAGGGIGGLAAAAALAGKGIASVVLEQAATMAEIGAGIQIGPNGFHCFDALGIGPQMRETAVFIDALRLLDAQTAEEITRIPLDAPFRAHFGNPYAVVHRAQLHQLLLQRCIDSGLVDLRTRQTARGYSQNGTSVTLHLKDTDVTGRALVGAEGLRSPIRAQMVGDGAPRVSGHATYRSVIPRDAMPEDLRMNAATLWAGPKCHIVHYPLKGGTVFNLVVTYHRDALEAVSGKPVTNAEVAEGFEHVHPRARAVIEHGRDWKQWVLCDRDPISSWTDERVALLGDAAHPMLQYFAQGACMAMEDGVALAVALDGAIDVEAALLRYQNMRAVRTARVQMNSRLIGDYIYHPDNARAAVRNEIMQGMSPQDWYEQLTWIYRSNGLPPDMGGI
>NC_007802.1|WP_011456030.1|2929583_2930276_+|fumarylacetoacetate-hydrolase-family-protein
MAYVFDPIAPPSVAVAGLTAHFPVRRIFCVGRNYAEHAREMGHDDREPPFFFTKPADALVEDGATVPYPPGTENLHFEAELVVAIGTPGRAIAEANALDHVYGYACGNDLTRRDIQTAAKKAGRPWDMAKGFDLSAVVGPIHPVSEVGHLERGRISLTRNGEVQQTGDLADMIWSTPEIIAYLSGLVGFEAGDLIMTGTPAGVGALVPGDTAVVSIAGLPDLSVTIGEPA
>NC_007802.1|WP_166486269.1|2930284_2931346_+|cupin-domain-containing-protein
MQAEDSPELRQLYKGFKGQSLIPLWTQTGSLMPQTPAPKAVPHVWRWADLLPLAQAAGTLVPVGRGGERRALGLANPGLAPNAYISPTLWCAIQYLMPRETAPEHRHAQNAFRFVVEGEGVWTVVDGDPVRMSRGDLLLTPGWRFHGHHNDRDAPMAWIDGLDIPFSQQMDVGFFEFGNEQVSDYSTPHFSRGERLWANPGLRPLSGLENTTASPLAAFRWEHTDRALAEQLLLEDEGHSATVEPGHAAIRYVNPTTGGDVMPTIRCEFHRLRAGCKTAMRREVGSTIFQVFDGRGAVVIDGVTHRLDKGDLFTVPSWISWSLEAEEPFDLFRFSDAPIMERLHFARTHIEES

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

966962 : 1033348

uncultured_Mediterranean_phage(25.0%)

protease,tRNA,holin

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_011454137.1\|966962_967661_+\|protease	M48 family metalloprotease	NA	NA	NA	NA
WP_011454138.1\|967667_968015_+	YigZ family protein	NA	NA	NA	NA
WP_011454139.1\|968161_969538_-	30S ribosomal protein S12 methylthiotransferase RimO	NA	NA	NA	NA
WP_011454140.1\|969680_971651_+	AsmA family protein	NA	NA	NA	NA
WP_011454141.1\|971647_972145_+	lytic transglycosylase domain-containing protein	J9SV57	Escherichia_phage	1.5e-07	36.7
WP_011454142.1\|972231_972723_-	hypothetical protein	NA	NA	NA	NA
WP_011454143.1\|972799_973162_-	VOC family protein	NA	NA	NA	NA
WP_011454144.1\|973177_973765_-	GcrA cell cycle regulator	NA	NA	NA	NA
WP_011454145.1\|973913_974975_+	serine hydrolase	NA	NA	NA	NA
WP_011454146.1\|974949_975876_-	DMT family transporter	NA	NA	NA	NA
WP_011454147.1\|975885_976812_-	ornithine carbamoyltransferase	M1I6M4	Paramecium_bursaria_Chlorella_virus	9.4e-19	26.1
WP_011454148.1\|976893_978081_-	aspartate aminotransferase family protein	A0A1V0SKB7	Klosneuvirus	2.3e-25	25.4
WP_011454149.1\|978162_978666_-	PaaI family thioesterase	NA	NA	NA	NA
WP_011454150.1\|978796_979663_-	methylenetetrahydrofolate reductase [NAD(P)H]	NA	NA	NA	NA
WP_011454151.1\|979756_980665_+	LysR family transcriptional regulator	NA	NA	NA	NA
WP_011454152.1\|980779_981574_+	inositol monophosphatase	NA	NA	NA	NA
WP_044006374.1\|981621_982317_-\|holin	phosphatidylcholine synthase	NA	NA	NA	NA
WP_011454154.1\|982397_983321_-	tyrosine recombinase XerC	A0A0K0MWE8	Gordonia_phage	3.3e-16	33.5
WP_011454155.1\|983325_984069_-	DUF484 family protein	NA	NA	NA	NA
WP_011454156.1\|984204_984858_-	fructose-6-phosphate aldolase	A0A0C5AMY8	Cyanophage	5.5e-50	47.6
WP_044007305.1\|984963_987153_+	primosomal protein N'	NA	NA	NA	NA
WP_011454158.1\|987218_988301_+	histidinol-phosphate transaminase	A0A1X7BZP2	Faustovirus	4.0e-21	28.6
WP_011454159.1\|988297_989230_+	prephenate/arogenate dehydrogenase family protein	NA	NA	NA	NA
WP_011454160.1\|989226_990183_+	extensin family protein	NA	NA	NA	NA
WP_011454161.1\|990225_991245_-	DUF2125 domain-containing protein	NA	NA	NA	NA
WP_011454162.1\|991419_991962_+	gamma-glutamylcyclotransferase	NA	NA	NA	NA
WP_011454163.1\|992038_993238_+	hypothetical protein	NA	NA	NA	NA
WP_011454164.1\|993241_995641_+	peptidoglycan -binding protein	NA	NA	NA	NA
WP_044007307.1\|995873_998207_-\|protease	ATP-dependent Clp protease ATP-binding subunit ClpA	A0A223W0B1	Agrobacterium_phage	2.9e-173	44.5
WP_011454166.1\|998404_999175_-	hydroxyacylglutathione hydrolase	NA	NA	NA	NA
WP_011454167.1\|999249_1000011_+	hypothetical protein	NA	NA	NA	NA
WP_011454168.1\|1000007_1000544_+	flavodoxin family protein	NA	NA	NA	NA
WP_011454170.1\|1000849_1001410_+	F0F1 ATP synthase subunit delta	NA	NA	NA	NA
WP_011454171.1\|1001409_1002948_+	F0F1 ATP synthase subunit alpha	NA	NA	NA	NA
WP_011454172.1\|1002960_1003851_+	F0F1 ATP synthase subunit gamma	NA	NA	NA	NA
WP_011454173.1\|1003868_1005293_+	F0F1 ATP synthase subunit beta	NA	NA	NA	NA
WP_011454174.1\|1005421_1005820_+	F0F1 ATP synthase subunit epsilon	NA	NA	NA	NA
WP_044006378.1\|1005969_1006320_+	H-type lectin domain-containing protein	NA	NA	NA	NA
WP_011454176.1\|1006401_1006974_+	hypothetical protein	NA	NA	NA	NA
WP_011454177.1\|1006979_1008008_-	ribose-phosphate pyrophosphokinase	A0A2K9L2G2	Tupanvirus	1.9e-44	37.8
WP_011454178.1\|1008140_1008740_+	2-hydroxychromene-2-carboxylate isomerase	NA	NA	NA	NA
WP_166486061.1\|1008736_1009498_+	alpha/beta fold hydrolase	NA	NA	NA	NA
WP_044006385.1\|1009657_1010752_+	AI-2E family transporter	NA	NA	NA	NA
WP_011454181.1\|1010751_1011453_+	chromosomal replication initiator DnaA	NA	NA	NA	NA
WP_011454182.1\|1011481_1013656_+	RNA degradosome polyphosphate kinase	NA	NA	NA	NA
WP_011454183.1\|1013713_1015282_+	Ppx/GppA family phosphatase	NA	NA	NA	NA
WP_166486062.1\|1015654_1015798_+	hypothetical protein	NA	NA	NA	NA
WP_011454184.1\|1015864_1017223_+\|tRNA	proline--tRNA ligase	NA	NA	NA	NA
WP_166486063.1\|1017320_1017497_+	hypothetical protein	NA	NA	NA	NA
WP_011454185.1\|1017588_1018767_-\|protease	trypsin-like serine protease	NA	NA	NA	NA
WP_011454186.1\|1018885_1020109_-\|protease	trypsin-like serine protease	NA	NA	NA	NA
WP_011454187.1\|1020337_1023670_-	carbamoyl-phosphate synthase large subunit	NA	NA	NA	NA
WP_011454188.1\|1023852_1024530_+	HAD hydrolase-like protein	NA	NA	NA	NA
WP_011454189.1\|1024548_1025670_-	peptidoglycan DD-metalloendopeptidase family protein	G9FHH0	Rhodococcus_phage	7.6e-07	35.0
WP_011454190.1\|1025898_1028751_+	Hint domain-containing protein	NA	NA	NA	NA
WP_011454191.1\|1028830_1029499_-	protein-L-isoaspartate(D-aspartate) O-methyltransferase	A0A1B1IU40	uncultured_Mediterranean_phage	1.2e-28	42.0
WP_011454192.1\|1029548_1030340_-	5'/3'-nucleotidase SurE	A0A1B1ITZ2	uncultured_Mediterranean_phage	4.2e-28	33.3
WP_044006387.1\|1030451_1031150_-	tryptophan-rich sensory protein	NA	NA	NA	NA
WP_011454194.1\|1031166_1032459_-\|tRNA	serine--tRNA ligase	A0A1B1IVT2	uncultured_Mediterranean_phage	9.5e-86	42.1
WP_166486064.1\|1032610_1033348_-\|protease	trypsin-like serine protease	NA	NA	NA	NA

DBSCAN-SWA_2

1462263 : 1507841

uncultured_Mediterranean_phage(42.86%)

tRNA,integrase,holin

attL 1472798:1472814|attR 1517392:1517408

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_011454616.1\|1462263_1463934_-\|holin	choline dehydrogenase	A0A1V0SI18	Klosneuvirus	1.0e-60	30.1
WP_011454617.1\|1463933_1465379_-	betaine-aldehyde dehydrogenase	NA	NA	NA	NA
WP_011454618.1\|1465401_1466910_-\|holin	choline-sulfatase	NA	NA	NA	NA
WP_011454619.1\|1466906_1467161_-	hypothetical protein	NA	NA	NA	NA
WP_011454620.1\|1467157_1467730_-	transcriptional regulator BetI	NA	NA	NA	NA
WP_011454621.1\|1467823_1468768_+\|holin	choline ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_011454622.1\|1468938_1469787_+	hemolysin-type calcium-binding protein	NA	NA	NA	NA
WP_044007379.1\|1469974_1470871_+\|holin	choline ABC transporter permease subunit	NA	NA	NA	NA
WP_011454624.1\|1470867_1471278_+	GFA family protein	NA	NA	NA	NA
WP_011454625.1\|1471274_1472318_+\|holin	choline ABC transporter ATP-binding protein	G3M9Y6	Bacillus_virus	1.0e-21	32.5
WP_011454626.1\|1472396_1473437_-	acyl-CoA dehydrogenase family protein	NA	NA	NA	NA
1472798:1472814	attL	NA	NA	NA	NA
WP_011454627.1\|1473433_1474615_-	acyl-CoA dehydrogenase family protein	NA	NA	NA	NA
WP_011454628.1\|1474682_1475012_-	iron-sulfur cluster assembly accessory protein	A0A2H4N7M3	Lake_Baikal_phage	8.2e-18	45.9
WP_011454629.1\|1475112_1476303_+	deoxyguanosinetriphosphate triphosphohydrolase	NA	NA	NA	NA
WP_011454630.1\|1476305_1476671_+	hypothetical protein	NA	NA	NA	NA
WP_011454631.1\|1476737_1478465_+\|tRNA	arginine--tRNA ligase	NA	NA	NA	NA
WP_011454632.1\|1478542_1479571_+	SPOR domain-containing protein	NA	NA	NA	NA
WP_011454633.1\|1479572_1480589_+	glycoside hydrolase family 3 protein	A0A1B1IVS3	uncultured_Mediterranean_phage	8.7e-18	40.0
WP_011454634.1\|1480575_1481388_+	segregation/condensation protein A	A0A1B1IVW1	uncultured_Mediterranean_phage	2.0e-33	33.3
WP_011454635.1\|1481384_1482071_+	SMC-Scp complex subunit ScpB	A0A1B1IVT7	uncultured_Mediterranean_phage	1.5e-37	43.0
WP_044006492.1\|1482128_1482326_+	hypothetical protein	NA	NA	NA	NA
WP_011454636.1\|1482633_1482828_+	hypothetical protein	NA	NA	NA	NA
WP_011454637.1\|1482937_1483537_+	SH3 domain-containing protein	NA	NA	NA	NA
WP_011454638.1\|1483698_1484433_-	VPLPA-CTERM sorting domain-containing protein	NA	NA	NA	NA
WP_011454639.1\|1484640_1486047_-	type I glutamate--ammonia ligase	NA	NA	NA	NA
WP_011454640.1\|1486104_1486443_-	P-II family nitrogen regulator	NA	NA	NA	NA
WP_011454641.1\|1486619_1488365_+	NAD(P)H-hydrate epimerase	NA	NA	NA	NA
WP_166486083.1\|1488470_1488962_-	Hint domain-containing protein	NA	NA	NA	NA
WP_011454643.1\|1489632_1490136_-	Lrp/AsnC family transcriptional regulator	NA	NA	NA	NA
WP_011454644.1\|1490183_1491113_+	EamA family transporter	NA	NA	NA	NA
WP_011454645.1\|1491385_1491982_-	hypothetical protein	NA	NA	NA	NA
WP_011454646.1\|1492005_1492458_-	Lrp/AsnC family transcriptional regulator	NA	NA	NA	NA
WP_011454647.1\|1492561_1493242_+	AzlC family ABC transporter permease	NA	NA	NA	NA
WP_044006499.1\|1493238_1493535_+	AzlD domain-containing protein	NA	NA	NA	NA
WP_011454648.1\|1493825_1494734_-	LysR family transcriptional regulator	NA	NA	NA	NA
WP_011454649.1\|1494830_1495841_+	SDR family oxidoreductase	NA	NA	NA	NA
WP_011454651.1\|1496167_1496782_-	TetR/AcrR family transcriptional regulator	NA	NA	NA	NA
WP_011454652.1\|1496876_1498922_+	NADH:flavin oxidoreductase	NA	NA	NA	NA
WP_011454653.1\|1498923_1499964_+	proline racemase family protein	NA	NA	NA	NA
WP_044007385.1\|1499972_1500908_+	ornithine cyclodeaminase family protein	NA	NA	NA	NA
WP_166486084.1\|1501350_1504317_+	hypothetical protein	NA	NA	NA	NA
WP_011454657.1\|1504313_1504763_+	response regulator	NA	NA	NA	NA
WP_011454658.1\|1504755_1505916_+	response regulator	NA	NA	NA	NA
WP_011454659.1\|1506206_1507016_+	DUF2927 domain-containing protein	NA	NA	NA	NA
WP_166486245.1\|1507244_1507841_+\|integrase	tyrosine-type recombinase/integrase	B3GAN2	uncultured_virus	1.9e-12	23.4
1517392:1517408	attR	NA	NA	NA	NA

DBSCAN-SWA_3

1620104 : 1637035

Dinoroseobacter_phage(40.0%)

protease,capsid,portal,tail,head

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_011454754.1\|1620104_1621265_+\|portal	phage portal protein	W8ECU7	Geobacillus_phage	6.8e-59	37.0
WP_011454755.1\|1621261_1621510_+	hypothetical protein	NA	NA	NA	NA
WP_011454756.1\|1621519_1622071_+\|head,protease	HK97 family phage prohead protease	A0A0U2BX10	Paracoccus_phage	1.3e-31	47.3
WP_011454757.1\|1622119_1623301_+\|capsid	phage major capsid protein	A0A2D1GNH4	Pseudomonas_phage	3.8e-65	39.4
WP_011454758.1\|1623463_1624051_+	hypothetical protein	NA	NA	NA	NA
WP_011454759.1\|1624047_1624374_+\|head	phage head closure protein	NA	NA	NA	NA
WP_011454760.1\|1624370_1624781_+	DUF3168 domain-containing protein	NA	NA	NA	NA
WP_011454761.1\|1624822_1625236_+\|tail	phage major tail protein, TP901-1 family	NA	NA	NA	NA
WP_011454762.1\|1625238_1625556_+	gene transfer agent family protein	NA	NA	NA	NA
WP_011454763.1\|1625552_1625777_+\|tail	phage tail assembly chaperone	NA	NA	NA	NA
WP_011454764.1\|1625760_1626429_+\|tail	phage tail tape measure protein	A0A1B2AQ26	Escherichia_phage	1.4e-11	32.8
WP_011454765.1\|1626441_1627074_+	DUF2460 domain-containing protein	A0A0B5A2K3	Paracoccus_phage	6.8e-61	54.8
WP_011454766.1\|1627070_1627949_+	DUF2163 domain-containing protein	A0A1V0DY93	Dinoroseobacter_phage	9.4e-53	43.0
WP_011454767.1\|1627945_1628380_+	peptidase	A0A1V0DYB6	Dinoroseobacter_phage	4.7e-29	47.1
WP_011454768.1\|1628381_1632833_+	glycoside hydrolase TIM-barrel-like domain-containing protein	A0A1V0DY94	Dinoroseobacter_phage	1.5e-194	32.5
WP_011454769.1\|1632825_1633533_+	DUF2793 domain-containing protein	A0A1V0DY81	Dinoroseobacter_phage	1.1e-27	33.3
WP_011454770.1\|1633635_1634454_+	serine O-acetyltransferase	NA	NA	NA	NA
WP_011454771.1\|1634476_1635166_-	hypothetical protein	NA	NA	NA	NA
WP_011454772.1\|1635214_1637035_-	translational GTPase TypA	A0A2K5B2A5	Erysipelothrix_phage	5.0e-24	40.7

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. NC_007801

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection

2. NC_007802

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Click the colored protein region to show detailed information

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection