CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NC_007954	Shewanella denitrificans OS217, complete genome	3 crisprs	cas3,PD-DExK,DEDDh,DinG,csa3	0	0	4	0

Results visualization

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CRISPR-Cas detection and classification

Crispr_ID: NC_007954_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_007954_1

950919-951019

Orphan

Consensus_repeat	Method
ATTGCCATGTTGGACAACCGATAAC	CRISPRCasFinder

1 spacers

The CRISPR arrays of NC_007954_1

>merge|NC_007954|1|950919-951019|CRISPRCasFinder
ATTGCCATGTTGGACAACCGATAACGGATTACGGATTACAGATTACAGATTACAGATGATGCTGCTTGAGTGAGCGATTGCCATGTTGGACAACCGACAAC

>NC_007954|1|1|950919-951019|CRISPRCasFinder
ATTGCCATGTTGGACAACCGATAAC	GGATTACGGATTACAGATTACAGATTACAGATGATGCTGCTTGAGTGAGCG
ATTGCCATGTTGGACAACCGACAAC

Protein	Signature genes	Signature genes Name	Protein_function
NC_007954.1\|WP_157599911.1\|941626_942418_+\|DIM/SIM/IMP-family-subclass-B1-metallo-beta-lactamase	unknown	unknown	gnl\|CDD\|293859
NC_007954.1\|WP_041405667.1\|946602_947073_-\|transcriptional-regulator-ArgR	unknown	unknown	gnl\|CDD\|179922
NC_007954.1\|WP_041405668.1\|956360_959249_+\|aminomethyl-transferring-glycine-dehydrogenase	unknown	unknown	gnl\|CDD\|235432
NC_007954.1\|WP_011495284.1\|951170_951746_+\|UPF0149-family-protein	unknown	unknown	gnl\|CDD\|234976
NC_007954.1\|WP_011495288.1\|955751_956141_+\|glycine-cleavage-system-protein-GcvH	unknown	unknown	gnl\|CDD\|234918
NC_007954.1\|WP_011495287.1\|954578_955673_+\|glycine-cleavage-system-aminomethyltransferase-GcvT	unknown	unknown	gnl\|CDD\|234742
NC_007954.1\|WP_011495273.1\|938056_939148_+\|redox-regulated-ATPase-YchF	unknown	unknown	gnl\|CDD\|236583
NC_007954.1\|WP_011495285.1\|951781_953047_+\|2-octaprenyl-6-methoxyphenyl-hydroxylase	unknown	unknown	gnl\|CDD\|273911
NC_007954.1\|WP_011495294.1\|965238_965946_-\|DUF4386-domain-containing-protein	unknown	unknown	gnl\|CDD\|379558
NC_007954.1\|WP_157599829.1\|941219_941567_+\|hypothetical-protein	unknown	unknown	unknown
NC_007954.1\|WP_011495292.1\|963342_964860_+\|filamentation-induced-by-cAMP-protein-Fic	unknown	unknown	gnl\|CDD\|225718
NC_007954.1\|WP_011495283.1\|950499_950808_-\|cell-division-protein-ZapA	unknown	unknown	gnl\|CDD\|377476
NC_007954.1\|WP_011495286.1\|953123_954341_+\|FAD-dependent-2-octaprenylphenol-hydroxylase	unknown	unknown	gnl\|CDD\|236341
NC_007954.1\|WP_011495290.1\|960046_961120_+\|nucleoid-associated-protein	unknown	unknown	gnl\|CDD\|377262
NC_007954.1\|WP_011495281.1\|948368_949121_+\|dihydromonapterin-reductase	unknown	unknown	gnl\|CDD\|180586
NC_007954.1\|WP_157599830.1\|962696_962879_-\|hypothetical-protein	unknown	unknown	unknown
NC_007954.1\|WP_041406044.1\|949498_950191_-\|5-formyltetrahydrofolate-cyclo-ligase	unknown	unknown	gnl\|CDD\|182385
NC_007954.1\|WP_011495278.1\|944094_946281_+\|OsmC-domain/YcaO-domain-containing-protein	unknown	unknown	gnl\|CDD\|132588
NC_007954.1\|WP_011495280.1\|947351_948287_+\|malate-dehydrogenase	unknown	unknown	gnl\|CDD\|235340
NC_007954.1\|WP_011495277.1\|942611_943904_+\|aminotransferase-class-I/II-fold-pyridoxal-phosphate-dependent-enzyme	unknown	unknown	gnl\|CDD\|180392

Protein	Function_ID	Function_description	E-value
NC_007954.1\|WP_157599911.1\|941626_942418_+\|DIM/SIM/IMP-family-subclass-B1-metallo-beta-lactamase	gnl\|CDD\|293859	cd16301, IMP_DIM-like_MBL-B1, IMP-1, DIM-1, GIM-1, SIM-1, TMB-1 and related metallo-beta-lactamases, subclass B1; MBL-fold metallo-hydrolase domain. Includes the acquired MBLs IMP-1(a beta-lactamase that is active on imipenem), DIM-1 (Dutch imipenemase), GIM-1 (German imipenemase), KHM-1 (Kyorin Health Science MBL 1), SIM-1 (Seoul imipenemase), and TMB-1 (Tripoli metallo-beta-lactamase). IMP-1, DIM-1, GIM-1, SIM-1, and TMB-1 are Class 1 integron-mediated MBLs, KMH-1 is plasmid-mediated. MBLs (class B of the Ambler beta-lactamase classification) are a diverse group of metallo-enzymes that are capable of catalyzing the hydrolysis of a wide range of beta-lactam antibiotics. MBLs have been divided into three subclasses B1, B2 and B3, based on sequence/structural relationships and substrates, with the B1 and B2 MBLs being most closely related to each other. This subgroup of acquired MBLs belongs to the B1 subclass. B1 enzymes are most active with two zinc ions bound in the active site, and have a broad-spectrum substrate profile.	2.30749e-135
NC_007954.1\|WP_041405667.1\|946602_947073_-\|transcriptional-regulator-ArgR	gnl\|CDD\|179922	PRK05066, PRK05066, transcriptional regulator ArgR.	2.6858e-112
NC_007954.1\|WP_041405668.1\|956360_959249_+\|aminomethyl-transferring-glycine-dehydrogenase	gnl\|CDD\|235432	PRK05367, PRK05367, aminomethyl-transferring glycine dehydrogenase.	0
NC_007954.1\|WP_011495284.1\|951170_951746_+\|UPF0149-family-protein	gnl\|CDD\|234976	PRK01736, PRK01736, hypothetical protein; Reviewed.	2.60857e-45
NC_007954.1\|WP_011495288.1\|955751_956141_+\|glycine-cleavage-system-protein-GcvH	gnl\|CDD\|234918	PRK01202, PRK01202, glycine cleavage system protein GcvH.	6.20313e-73
NC_007954.1\|WP_011495287.1\|954578_955673_+\|glycine-cleavage-system-aminomethyltransferase-GcvT	gnl\|CDD\|234742	PRK00389, gcvT, glycine cleavage system aminomethyltransferase GcvT.	0
NC_007954.1\|WP_011495273.1\|938056_939148_+\|redox-regulated-ATPase-YchF	gnl\|CDD\|236583	PRK09601, PRK09601, redox-regulated ATPase YchF.	0
NC_007954.1\|WP_011495285.1\|951781_953047_+\|2-octaprenyl-6-methoxyphenyl-hydroxylase	gnl\|CDD\|273911	TIGR01984, 2-polyprenyl-6-methoxyphenol_hydroxylase, 2-polyprenyl-6-methoxyphenol 4-hydroxylase. This model represents the FAD-dependent monoxygenase responsible for the second hydroxylation step in the aerobic ubiquinone bioynthetic pathway. The scope of this model is limited to the proteobacteria. This family is closely related to the UbiF hydroxylase which catalyzes the final hydroxylation step. The enzyme has also been named VisB due to a mutant VISible light sensitive phenotype. [Biosynthesis of cofactors, prosthetic groups, and carriers, Menaquinone and ubiquinone].	3.54407e-164
NC_007954.1\|WP_011495294.1\|965238_965946_-\|DUF4386-domain-containing-protein	gnl\|CDD\|379558	pfam14329, DUF4386, Domain of unknown function (DUF4386). This family of proteins is functionally uncharacterized. This family of proteins is found in bacteria, archaea and eukaryotes. Proteins in this family are typically between 214 and 245 amino acids in length.	4.65596e-37
NC_007954.1\|WP_011495292.1\|963342_964860_+\|filamentation-induced-by-cAMP-protein-Fic	gnl\|CDD\|225718	COG3177, COG3177, Fic family protein [Function unknown].	2.2816e-11
NC_007954.1\|WP_011495283.1\|950499_950808_-\|cell-division-protein-ZapA	gnl\|CDD\|377476	pfam05164, ZapA, Cell division protein ZapA. ZapA is a cell division protein which interacts with FtsZ. FtsZ is part of a mid-cell cytokinetic structure termed the Z-ring that recruits a hierarchy of fission related proteins early in the bacterial cell cycle. The interaction of FtsZ with ZapA drives its polymerization and promotes FtsZ filament bundling thereby contributing to the spatio-temporal tuning of the Z-ring.	6.44769e-21
NC_007954.1\|WP_011495286.1\|953123_954341_+\|FAD-dependent-2-octaprenylphenol-hydroxylase	gnl\|CDD\|236341	PRK08850, PRK08850, 2-octaprenyl-6-methoxyphenol hydroxylase; Validated.	0
NC_007954.1\|WP_011495290.1\|960046_961120_+\|nucleoid-associated-protein	gnl\|CDD\|377262	pfam04245, NA37, 37-kD nucleoid-associated bacterial protein.	2.32713e-34
NC_007954.1\|WP_011495281.1\|948368_949121_+\|dihydromonapterin-reductase	gnl\|CDD\|180586	PRK06483, PRK06483, dihydromonapterin reductase; Provisional.	2.14206e-145
NC_007954.1\|WP_041406044.1\|949498_950191_-\|5-formyltetrahydrofolate-cyclo-ligase	gnl\|CDD\|182385	PRK10333, PRK10333, 5-formyltetrahydrofolate cyclo-ligase family protein; Provisional.	1.84434e-55
NC_007954.1\|WP_011495278.1\|944094_946281_+\|OsmC-domain/YcaO-domain-containing-protein	gnl\|CDD\|132588	TIGR03549, TIGR03549, YcaO domain protein. This family consists of remarkably well-conserved proteins from gamma and beta Proteobacteria, heavily skewed towards organisms of marine environments. Its gene neighborhood is not conserved. This family has an OsmC-like N-terminal domain. It shares a YcaO domain, frequently associated with ATP-dependent cyclodehydration for peptide modification. The function is unknown. Fifteen of the first sixteen members of this family are from selenouridine-positive genomes, but this correlation may not be meaningful.	0
NC_007954.1\|WP_011495280.1\|947351_948287_+\|malate-dehydrogenase	gnl\|CDD\|235340	PRK05086, PRK05086, malate dehydrogenase; Provisional.	0
NC_007954.1\|WP_011495277.1\|942611_943904_+\|aminotransferase-class-I/II-fold-pyridoxal-phosphate-dependent-enzyme	gnl\|CDD\|180392	PRK06084, PRK06084, bifunctional O-acetylhomoserine aminocarboxypropyltransferase/cysteine synthase.	0

>NC_007954.1|WP_011495283.1|950499_950808_-|cell-division-protein-ZapA
MSNSAIDITLLGRTYSIACPRGREEALRAVAKEVEQQLATLRTRTNNLSREELAIMAALNIGYELFEEKQKNKQYMAQMDERISLLQVTLESALVERTRKED
>NC_007954.1|WP_041406044.1|949498_950191_-|5-formyltetrahydrofolate-cyclo-ligase
MAASDPISNVAYFSSSAANSQALDTTDLSRNEIRKLVRQSRNCINQDEQEQLALIASRHILAEIQASNAKHVALYRANDGELATDKLIETLWQEGVTTYLPRLHPFREGQLIFLHYDKQTQLEANQFGILEPKLDVTQLMPAFKLDVILTPLVAFDIHGNRIGMGGGYYDRCLGALTPQALAFGPPAFQALTPPIAIGFAHDCQQVSHIPVEAWDIPLAMIITPTRRITP
>NC_007954.1|WP_011495281.1|948368_949121_+|dihydromonapterin-reductase
MSQTLLITGVGKRIGYALAKDLLAKGHRVIGTYRSHYPSIDELGQLGASVYQCDLTHEAALDEVLNRIKQQHQQLDGIIHNASDWLGDNNGLSPADTMARMMQIHVTAPYQINLSLAPLLTQAALGASSTDKSAAIGASNIIHITDYVAEKGSKKHIAYAASKAALHNMTLSFAAKFAPEIKVNSIAPAMILFNEGDDAAYQAKTLAKAILPKEAGTEEIIAVVDYLLGSHYVTGRSFAVDGGRHLYQSH
>NC_007954.1|WP_011495280.1|947351_948287_+|malate-dehydrogenase
MKVAVLGAAGGIGQALALLLKTQLPAGSKLSLYDIAPVTPGVAVDLSHIPTAVEIKGFAGEDPTPALVDADVVLISAGVARKPGMDRSDLFNINAGIVRNLMEKVAATCPKALVGIITNPVNTTVAIAAEVMKKAGVYDKNRLFGVTTLDVIRSETFIAELKGLNVADVNINVIGGHSGVTILPLLSQVKGVSFTDEEVAALTKRIQNAGTEVVEAKAGGGSATLSMGQAACRFGLSLVRGLQGEANVVECAYVDGGSEHAQFFAQPILLGKNGVEKVMPYGEVSAFEANARDAMLDTLNADIKLGVEFVK
>NC_007954.1|WP_041405667.1|946602_947073_-|transcriptional-regulator-ArgR
MSAPKQQDELVRTFKALLKDESFASQSEIVTALQAEGFGNINQSKVSRMLSKFGAVRTRNAKQEMVYCLPAELGVPTAGSPVKNLVLDVDHNQAMIVVRTSPGAAQLIARLLDSIGKPEGILGTIAGDDTIFICPASIKTIDDTLETVKSLFNYTE
>NC_007954.1|WP_011495278.1|944094_946281_+|OsmC-domain/YcaO-domain-containing-protein
MEIKVNFLDNLRLEAKFDDFTVTADQPIRYKGDGSAPSPFDYFLASSALCAAYFIKVYCKARDISTENIKLSQNNIVDPEDRYNQIFQIQVELPDDISDKDREGILRSIDRCTVKKVIQTGPEFNVETVENLSADANAMLMGSSDQDASTFILGKDLPLEQTIANMTAMLAELGMKIEISSWRNIVPNVWSLHIRDAASPMCFTNGKGASKESALCSALGEFIERLNNNFFYNDQFFGTEIANSEFVHYPNEKWFPLEDDDALPAGMLDDYCLEIYNQDDELQGSHLIDTNSGNRERGICAIPYKRKSDGQTVYFPSNLIENLFLSNGMSAGNNLQEAEVQCLSEIFERAVKRQIIEQEIVLPDVPMSVLEKYPSILAGIKGLEEQGFPIVVKDASLGGQFPVMCVTLMNPRTGGVFASFGAHPSFEVALERSLTELLQGRSFEGLNDVPKPTFNSMAVTEPENFVEHFIDSTGVISWRFFSSKHDYDFCEWDFSGTSEEEAKGLFAILEAMGKEVYIAEFTELGASACRMLVPDYSEVYPVDDLIWDNTNKALLYREDILNLHSLSTKALVKLVNRLEESQLDNHTDIRTLIGIVFDENTVWGKLTIIELKIMIYLALGSHEDAIELVGEFLQFNDNTVQRGLFYQAVSAVLEVTLDEDLELEHFIESFNRMYGKDVMDNVVGSVNGTVRFYGLTKTSMQLEGIEPHLRLIESYKKLHQARKIKAGL
>NC_007954.1|WP_011495277.1|942611_943904_+|aminotransferase-class-I/II-fold-pyridoxal-phosphate-dependent-enzyme
MKLESLALHFGYTSEASTKAAAVPIYQTTSYTFDDTQHGADLFDLKVAGNIYTRIMNPTTDVLEQRLAAIEGGIGALAVASGMAAITYAIAALTQVGDNIVSTSQLYGGTYNLFAHTLPRQGVEVRMAAFDAFDELEALIDDKTKALFCESIGNPAGNIVDLQALAEIAHRHGVPLIVDNTVATPVLCRPFEHGADIVIHSLTKYIGGHGTTIGGAIIDSGKFDWVANKDRFALLNEPDPSYHGVVYTQAFGPAAFIGRCRVVPLRNTGAALAPHSAFLLLQGLETLSLRMERHCSNALALAQYLQQHPNVSWVNYGALENSPYKDNCNKITSGQASGIVSFGIKTQANQNSTVAGGRFIDALKMILRLVNIGDAKSLACHPASTTHRQLSPEELAKAGVSEDLIRISVGIEHIDDIIADVEQALAASVS
>NC_007954.1|WP_157599911.1|941626_942418_+|DIM/SIM/IMP-family-subclass-B1-metallo-beta-lactamase
MLNLVRKVFTTGPRVLSVVSLLSVNVLGINLAQAVTSEESVPKFSIEPLANNVYLHQSFQQTESFGLVGANGLVVINEGKAFIVDTPWSESDTAVLVDWIKEQGYQLVGSVSTHSHEDRTAGIGWLNAHSIPTFASELTNQILKESEKPLASHPFALPQASLFDGQLEAFYPGGGHALDNLVVWLPKSNILFGGCLVRSLDSTSLGYTGEAVLEQWPTSAMKVLAKFPDVELVVPGHGEPGDKQLLIHTKALAESGAKQASAK
>NC_007954.1|WP_157599829.1|941219_941567_+|hypothetical-protein
MMTISLIFLIGYLLLAGVAWFNASRRGSLHWCDLSAPVLIPLFWVALVVAGVGHQSLTHLIEIPILLGIIALLLNIRVFVIDAIQTNTKLNAYIVLGLGLISVLLVRSFMPFLAE
>NC_007954.1|WP_011495273.1|938056_939148_+|redox-regulated-ATPase-YchF
MGFKCGIVGLPNVGKSTLFNALTQAGIEAANFPFCTIEPNTGVVPVPDPRLDALAAIVNPQRVIPTSMEFVDIAGLVAGASKGEGLGNKFLANIRETDAIGHVVRCFEDPNIVHVANKVDPAGDIEVINTELALADLDSLERAVFRQQKKAKGGDKDAKFEIEVLEKMRPTLDEAKMLRSLDLSKEELAAVAYLNFLTLKPTMYIANVAEDGFENNPHLDAVRAIAATENAVVVAVCAAIESELAEMEADERDEFMADLGIEEPGLDRVIRAGYSLLNLQTYFTAGVKEVRAWTVPIGASAPQAAGVIHTDFERGFIRAQVMAYDDFITYKGEAGAKDAGKLKVEGKTYIVKDGDVMHFLFNV
>NC_007954.1|WP_011495284.1|951170_951746_+|UPF0149-family-protein
MATPPSLCIDNLKQALDKADIGQHPVEVHGALVGLVCGGVEQESFAWVKPLLDLMNDGETLPQELQLLIIDLFQDTVARLGDMDFGFTPLLPEEEASLSERVEALSLWAQSFLTGLAIIQPKLNSASADVQEVIKDLAEIAQVEFDVSDDEESEAAFVELHEFVRMAAILCYSEFGPEPELGDNEQSAALH
>NC_007954.1|WP_011495285.1|951781_953047_+|2-octaprenyl-6-methoxyphenyl-hydroxylase
MSELQAQSQINAVDIAIVGGAMAGSILALGLRKLKGSQPLKIALIEAFEPSASHPGFDARSIALSHGSIFELTRLGLWEKLAPLGTAIEHIHVSDRGHLGMTCLDAAQFNLAAMGQVVELSRVGSVLFDELSQSDISLYCPDTLISIAAEPEHQLLTLASGARIQAKLLIAADGANSVVAQHFKLPRTQVDFNQTALVANIVSQDAHQHQAFERFTDTGPLALLPMADNAGKHRFSLVWALEPQRAAHLADAPKDEFLSQLQQAFGYRAGQFIDVGQRVSYPLSLSYMPRPQHHRCLFVGNAAQTLHPIAGQGFNLGLRDVVSLIDMLADALAESMATQECQLTQTTKELDCGNSKLLHQYSLARESDRRSTLSYIEFLVRGFSNQHWPLVAGRNLGLRLLSWCPPLKQPVGQRAMGWHKY
>NC_007954.1|WP_011495286.1|953123_954341_+|FAD-dependent-2-octaprenylphenol-hydroxylase
MFSTQTFDVAIVGGGMVGLATAIGLALNDMNVVVIDAGHTLDVSGEPKLRVSAINHASQQLLENLGAWGYLDSSRLSPYSKMAVWDKDGLGKIGFDAHTLAQAHLGTIVENQAISAALASRASELSSLHHIQGQRLERLAFGEREAWLTLDNGDSISAAVVIAADGAHSWVREQCKIPQTFWDYGHHAIVATVRTAEPHQDTARQVFLPDGPLALLPLFEANLHSIVWSVPPEQASRLLNMDKDEFSKALTAAFDARLGVCTLVSERQSHPLRMRYARHFARHRLILAGDAAHTIHPLAGQGVNLGFLDAASIVQTLTELNEQGRDLGDYANLRPLERWRKAEAMEMIAAMEGFKRLFEGSNPLKKAIRDLGLNLVDNVAGLKTVFIKQAMGYKSDLPKLCRPSN
>NC_007954.1|WP_011495287.1|954578_955673_+|glycine-cleavage-system-aminomethyltransferase-GcvT
MANKTVLFHKHLESNAKMVDFHGWDMPLNYGSQIEEHHAVRQDAGMFDVSHMTVVDVTGQDARDFLRKLLANDVAKLTVPGKALYGGMLDDNAGVIDDLITYYLSDTHYRVVVNSATREKDLAWIAKQSAPFSVTITERPELAMIAVQGPNAKAKAATVFTPEQNSAVEGMKPFFGLQSGSLFIATTGYTGEAGYEIIVPEQDAEDLWQALLNTGVKPCGLGARDTLRLEAGMNLYGLDMDESINPLAANMGWTIAWEPSDRDFIGRAALTELKAQGTEKLVGLVMEEKGVLRHDMPVFFTDSDGVEQQGYITSGTFSPTLGYSIAMARVPAGIGAIAEVEMRKKRVAVKVIAPSFVRNGKQAF
>NC_007954.1|WP_011495288.1|955751_956141_+|glycine-cleavage-system-protein-GcvH
MSTIPTDLKFASSHEWVRKEDDGSYTVGITEHAQELLGDMVFVELPEVGDSVSAGAECAVAESVKAASDIYAPISGEVVAVNSSLEDSPELVNSDAYGDGWFFRIMPSDESEVDALLDAEGYQDVIDEA
>NC_007954.1|WP_041405668.1|956360_959249_+|aminomethyl-transferring-glycine-dehydrogenase
MTKQTLTQLEQHELFLTRHIGPNAAQQQEMLSFVGAESLDDLTAQTVPGAIRLPQDLTIGDSCGEAEGIAYIRNIADKNKVFKSYIGMGYYGVQVPNVILRNVFENPGWYTAYTPYQPEIAQGRLEAILNFQQMSMDLTGLDLASASLLDEASAGAEAMALAKRVSKAKKANIFFVADDVFPQTLDVVQTRAECFGFEVVVGPAADAVNYELFGALFQYSNRHGQISDFTALFSELRAKNVVVTVAADLMALMLLKSPGAMGADVVFGSAQRFGVPMGYGGPHAAFFVARDEHKRSMPGRIIGVSKDTRGNMALRMAMQTREQHIRREKANSNICTAQILLANMASFYAVFHGPQGLKTIATRINRLADILAFGLKAKGLSLVNDAWFDTVSVKGADIGAIQARAIAAGINLRIDADGVFGISLDETTLRSDIADLFDAILGAGHGLDVAAIDAQLVAANSSSIPAALVRTDAVLTHPTFNRYQSETEMMRYIKRLENKDLALNHSMISLGSCTMKLNAAVEMLPVSWPEFANMHPFCPLDQAEGYTQLINELSEYLVKITGYDAVCIQPNSGAQGEYAGLLAIKKYHESRGDAHRDICLIPQSAHGTNPASAQLAGMKVVVTACDKQGNVDLDDLRAKASELADSLSCIMITYPSTHGVYEESIREVCDIVHQYGGQVYLDGANMNAQVGLTSPGFIGADVSHLNLHKTFAIPHGGGGPGMGPIGVKSHLAPFVAGHTVVKPGRESDHNGAVSAAPYGSASILPISWMYIKLLGTKGIKQSTQTALLNANYVMKKLSAHYPVLFTGRNDRVAHECIIDLRPLKEASGVTEMDIAKRLNDYGFHAPTMSFPVAGTLMIEPTESESKVELDRFIEAMVSIRGEIAKVESGEWPVDNNPLHNAPHTMADIMDPEFDSRPYSREVAVFPSAAVKANKFWPTVNRIDDVYGDRNLMCSCVPLSDYE
>NC_007954.1|WP_011495290.1|960046_961120_+|nucleoid-associated-protein
MASIKRFVIHELFKDKKPDIAGELLNLDNEIILKLAKDLVKIKDGRTAVLWGQFKGSGDFPLKLKELDAELKEDERSVKLLELTEHTMGALYEEIVHTNSKGGYICFIEYESFLDCRLMAAMITNTAGVKLTNLKPTKEVHVDLSKLHQAVDINVSGYSKSIKGDFKKNYLSFIGKGTHTDYFTNAFDCINKITPAKAVNKAPEVLKDFLAQFYVDNTTQKSARAQLVKYLSDNIGKEVHLAKIDEIAVSNLPASCTDEEKQSFIAFSKQDKYEMPATFEARKSNVEKLAKIYYATDAFNFNFDLENIGLVGVEADSNKPILFNKDNDDVIIRGRMITPEVRAAIIQVTLLNEDEND
>NC_007954.1|WP_157599830.1|962696_962879_-|hypothetical-protein
MAHIAFKDENDNPTLSTTPPSLLASKRIATRSSRACICISDHTSDGTCISRTGSSNGWHG
>NC_007954.1|WP_011495292.1|963342_964860_+|filamentation-induced-by-cAMP-protein-Fic
MNPVSQKLADSLEQLKLLQESGSVAIQSKQLSRLHRERLLKHGFIREVIRGWYIPAMPDEKLGDSTSWYTCFWDFCGAYLSERFDQSWCLSPEQSINHHIGDKTVPQQLLVRSPKGNNKPTDFLYNTSIFDVRLNLPDVEHIQSLAGLNIYSLPAAVVYCSPKSFVNSPIQMRTALSMVTDASDLLSILLAANHSVIAGRLVGAFRNIGRDLIADNILKGMNAADLVVLEEDPFVEKVQLNLGRRDVSPYVNRIRLMWAQMREDVIAHFPEPMNQTVDIDTYMAEVEEQYVTDAYHSLSIEGYRVTRELIELVRSGSWQADDGSGESKKYLDAMAAKGYWDAFGEVKKTVRAVLEGKNPGDMLERAHSDWYLALFGPSVAAGIIKQSDLAGYRTGPVYIRQSMHTPPSRDAVRTMMPTLFDLLAQEENAAVRLVLGHFIFVYIHPYFDGNGRMGRFIMNLMMASGAYPWTVVPVERRSEYMQALESASVKQDIVPFTQFLASLLL
>NC_007954.1|WP_011495294.1|965238_965946_-|DUF4386-domain-containing-protein
MIDKSTTSSTNIYTKVAGITYILIIILALIPSSIFDIGSMLKAKDAAKNLVGHEGIFRIGIAIEFMMFLLVMVLSWALYVILKPVNKNLALLGLIFRFGEAILGCVIIVFYLMVLMFLGGAEYLQVFEAEQLQALARFSLILSGVGYHILLTVMGIGGLVFCYLFYISTYIPRPLAAWGIITYLTMIIYGFINIALQNPQSELAYAMAPGALFEVIIGFWLLFKGVNVNQQKQPQ

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Crispr_ID: NC_007954_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_007954_2

2264497-2264596

Orphan

Consensus_repeat	Method
TAGGGAAAACATAACCCTCAGCCCA	CRISPRCasFinder

1 spacers

The CRISPR arrays of NC_007954_2

>merge|NC_007954|2|2264497-2264596|CRISPRCasFinder
TAGGGAAAACATAACCCTCAGCCCATGGCCCTGGGCCTCCCAAAGCTGAAGCAGGTGGGGGCGTAGTTGTCGTCGTAGGGAAAACATAACCGTCAGCCCA

>NC_007954|2|2|2264497-2264596|CRISPRCasFinder
TAGGGAAAACATAACCCTCAGCCCA	TGGCCCTGGGCCTCCCAAAGCTGAAGCAGGTGGGGGCGTAGTTGTCGTCG
TAGGGAAAACATAACCGTCAGCCCA

Protein	Signature genes	Signature genes Name	Protein_function
NC_007954.1\|WP_083759649.1\|2256322_2259184_-\|PAS-domain-S-box-protein	unknown	unknown	gnl\|CDD\|274362
NC_007954.1\|WP_011496365.1\|2282375_2284124_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|379155
NC_007954.1\|WP_011496372.1\|2289830_2290049_-\|DUF4287-domain-containing-protein	unknown	unknown	gnl\|CDD\|379478
NC_007954.1\|WP_011496364.1\|2280897_2282376_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|379155
NC_007954.1\|WP_011496366.1\|2284232_2285378_-\|tetratricopeptide-repeat-protein	unknown	unknown	gnl\|CDD\|274350
NC_007954.1\|WP_041405756.1\|2263248_2263854_-\|hypothetical-protein	unknown	unknown	unknown
NC_007954.1\|WP_041405755.1\|2260582_2261938_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|179385
NC_007954.1\|WP_011496373.1\|2290737_2291088_-\|hypothetical-protein	unknown	unknown	unknown
NC_007954.1\|WP_011496367.1\|2285897_2286785_-\|IS982-like-element-ISSde7-family-transposase	unknown	unknown	gnl\|CDD\|372648
NC_007954.1\|WP_049762999.1\|2254524_2255340_-\|Crp/Fnr-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|223736
NC_007954.1\|WP_011496363.1\|2279500_2280901_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|379155
NC_007954.1\|WP_011496358.1\|2259884_2260592_-\|hypothetical-protein	unknown	unknown	unknown
NC_007954.1\|WP_011496356.1\|2255351_2256263_-\|response-regulator	unknown	unknown	gnl\|CDD\|381103
NC_007954.1\|WP_011496360.1\|2262133_2263111_-\|hypothetical-protein	unknown	unknown	unknown
NC_007954.1\|WP_011496353.1\|2250616_2252404_-\|DUF3494-domain-containing-protein	unknown	unknown	gnl\|CDD\|378786
NC_007954.1\|WP_011496370.1\|2288470_2289295_-\|AraC-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|378964
NC_007954.1\|WP_011496354.1\|2252859_2254308_-\|DUF3494-domain-containing-protein	unknown	unknown	gnl\|CDD\|378786
NC_007954.1\|WP_011496371.1\|2289436_2289787_-\|glyoxalase	unknown	unknown	gnl\|CDD\|319903
NC_007954.1\|WP_011496368.1\|2287175_2287697_-\|DUF1643-domain-containing-protein	unknown	unknown	gnl\|CDD\|377919
NC_007954.1\|WP_011496352.1\|2248891_2250421_+\|aminodeoxychorismate-synthase-component-I	unknown	unknown	gnl\|CDD\|185362

Protein	Function_ID	Function_description	E-value
NC_007954.1\|WP_083759649.1\|2256322_2259184_-\|PAS-domain-S-box-protein	gnl\|CDD\|274362	TIGR02956, sensor_protein_TorS, TMAO reductase sytem sensor TorS. This protein, TorS, is part of a regulatory system for the torCAD operon that encodes the pterin molybdenum cofactor-containing enzyme trimethylamine-N-oxide (TMAO) reductase (TorA), a cognate chaperone (TorD), and a penta-haem cytochrome (TorC). TorS works together with the inducer-binding protein TorT and the response regulator TorR. TorS contains histidine kinase ATPase (pfam02518), HAMP (pfam00672), phosphoacceptor (pfam00512), and phosphotransfer (pfam01627) domains and a response regulator receiver domain (pfam00072). [Signal transduction, Two-component systems].	1.62623e-59
NC_007954.1\|WP_011496365.1\|2282375_2284124_-\|hypothetical-protein	gnl\|CDD\|379155	pfam13385, Laminin_G_3, Concanavalin A-like lectin/glucanases superfamily. This domain belongs to the Concanavalin A-like lectin/glucanases superfamily.	5.98584e-16
NC_007954.1\|WP_011496364.1\|2280897_2282376_-\|hypothetical-protein	gnl\|CDD\|379155	pfam13385, Laminin_G_3, Concanavalin A-like lectin/glucanases superfamily. This domain belongs to the Concanavalin A-like lectin/glucanases superfamily.	4.64265e-13
NC_007954.1\|WP_011496366.1\|2284232_2285378_-\|tetratricopeptide-repeat-protein	gnl\|CDD\|274350	TIGR02917, TPR_domain_protein, putative PEP-CTERM system TPR-repeat lipoprotein. This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.	1.76939e-18
NC_007954.1\|WP_041405755.1\|2260582_2261938_-\|hypothetical-protein	gnl\|CDD\|179385	PRK02224, PRK02224, DNA double-strand break repair Rad50 ATPase.	0.000359363
NC_007954.1\|WP_049762999.1\|2254524_2255340_-\|Crp/Fnr-family-transcriptional-regulator	gnl\|CDD\|223736	COG0664, Crp, cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms].	2.15461e-22
NC_007954.1\|WP_011496363.1\|2279500_2280901_-\|hypothetical-protein	gnl\|CDD\|379155	pfam13385, Laminin_G_3, Concanavalin A-like lectin/glucanases superfamily. This domain belongs to the Concanavalin A-like lectin/glucanases superfamily.	4.29079e-20
NC_007954.1\|WP_011496372.1\|2289830_2290049_-\|DUF4287-domain-containing-protein	gnl\|CDD\|379478	pfam14117, DUF4287, Domain of unknown function (DUF4287). This family of proteins is functionally uncharacterized. This family of proteins is found in bacteria. Proteins in this family are typically between 70 and 180 amino acids in length.	3.25858e-26
NC_007954.1\|WP_011496356.1\|2255351_2256263_-\|response-regulator	gnl\|CDD\|381103	cd17551, REC_RpfG-like, phosphoacceptor receiver (REC) domain of cyclic di-GMP phosphodiesterase response regulator RpfG and similar proteins. Cyclic di-GMP phosphodiesterase response regulator RpfG, together with sensory/regulatory protein RpfC, constitute a two-component system implicated in sensing and responding to the diffusible signal factor (DSF) that is essential for cell-cell signaling. RpfC is a hybrid sensor/histidine kinase that phosphorylates and activates RpfG, which degrades cyclic di-GMP to GMP, leading to the activation of Clp, a global transcriptional regulator that regulates a large set of genes in the DSF pathway. RpfG contains a CheY-like receiver domain attached to a histidine-aspartic acid-glycine-tyrosine-proline (HD-GYP) cyclic di-GMP phosphodiesterase domain. REC domains function as phosphorylation-mediated switches within response regulators, but some also transfer phosphoryl groups in multistep phosphorelays.	6.76217e-55
NC_007954.1\|WP_011496367.1\|2285897_2286785_-\|IS982-like-element-ISSde7-family-transposase	gnl\|CDD\|372648	pfam13612, DDE_Tnp_1_3, Transposase DDE domain. Transposase proteins are necessary for efficient DNA transposition. This domain is a member of the DDE superfamily, which contains three carboxylate residues that are believed to be responsible for coordinating metal ions needed for catalysis. The catalytic activity of this enzyme involves DNA cleavage at a specific site followed by a strand transfer reaction.	4.3375e-101
NC_007954.1\|WP_011496353.1\|2250616_2252404_-\|DUF3494-domain-containing-protein	gnl\|CDD\|378786	pfam11999, DUF3494, Protein of unknown function (DUF3494). This family of proteins is functionally uncharacterized. This protein is found in bacteria, archaea and eukaryotes. Proteins in this family are typically between 243 to 678 amino acids in length. This protein has a single completely conserved residue G that may be functionally important.	1.39343e-54
NC_007954.1\|WP_011496370.1\|2288470_2289295_-\|AraC-family-transcriptional-regulator	gnl\|CDD\|378964	pfam12833, HTH_18, Helix-turn-helix domain.	1.51481e-09
NC_007954.1\|WP_011496354.1\|2252859_2254308_-\|DUF3494-domain-containing-protein	gnl\|CDD\|378786	pfam11999, DUF3494, Protein of unknown function (DUF3494). This family of proteins is functionally uncharacterized. This protein is found in bacteria, archaea and eukaryotes. Proteins in this family are typically between 243 to 678 amino acids in length. This protein has a single completely conserved residue G that may be functionally important.	1.51775e-54
NC_007954.1\|WP_011496371.1\|2289436_2289787_-\|glyoxalase	gnl\|CDD\|319903	cd07238, VOC_like, uncharacterized subfamily of vicinal oxygen chelate (VOC) family. The vicinal oxygen chelate (VOC) superfamily is composed of structurally related proteins with paired beta.alpha.beta.beta.beta motifs that provide a metal coordination environment with two or three open or readily accessible coordination sites to promote direct electrophilic participation of the metal ion in catalysis. VOC domain is found in a variety of structurally related metalloproteins, including the bleomycin resistance protein, glyoxalase I, and type I ring-cleaving dioxygenases. A bound metal ion is required for protein activities for the members of this superfamily. A variety of metal ions have been found in the catalytic centers of these proteins including Fe(II), Mn(II), Zn(II), Ni(II) and Mg(II). The protein superfamily contains members with or without domain swapping. The proteins of this family share three conserved metal binding amino acids with the type I extradiol dioxygenases, which shows no domain swapping.	4.78138e-52
NC_007954.1\|WP_011496368.1\|2287175_2287697_-\|DUF1643-domain-containing-protein	gnl\|CDD\|377919	pfam07799, DUF1643, Protein of unknown function (DUF1643). The members of this family are all sequences found within hypothetical proteins expressed by various bacterial species. The region concerned is approximately 150 residues long.	2.9704e-09
NC_007954.1\|WP_011496352.1\|2248891_2250421_+\|aminodeoxychorismate-synthase-component-I	gnl\|CDD\|185362	PRK15465, pabB, aminodeoxychorismate synthase component 1.	4.33448e-177

>NC_007954.1|WP_041405756.1|2263248_2263854_-|hypothetical-protein
MSDFTFAMQDSADEVRSRVHVHGGEVWFSFLNPMSRTCLLVNYEHVSFFKKGVLTSLLPSLFLAAIGTFYSLKNGASKEIELLVSIPILISYVVIIFIYIRTVLKSERIQLDYNPFIEIAKNLALRMTIRNLIKSFILMGGFVLAIFIGALVIYAKGFYIIATIIFTVVGLSLSPILLVFIALVKWTGLRQGKEKKRSHLG
>NC_007954.1|WP_011496360.1|2262133_2263111_-|hypothetical-protein
MPRPRRSQVSVEDTPMYHCCSRVIRRAFLCGDDMFSGKNYDHRRAWVEAQLLKLAEVFAIDVAAFAVMSNHLHVVLSIDIYQANSWSDVEVISHWHQLFKGTDTTKKFAQGETLEDYEQLQLSHTVALYRSRLSDISWFMRCLNEPIARQANQEDNCTGRFWEGRFKSQALLDEAAVLACMAYVDLNPIRAKMADTPEYSDHTSIQLRIKAALKGEQPNNLLPFIGNERKNQPKGIAFALKDYLELVDDTGRIIRNDKRGAISTNSAKLLTRLNIPQENWLKLTTEFGKLFHGPVGTLQELTRYCEHLEKRRRHFASCCQHLKAG
>NC_007954.1|WP_041405755.1|2260582_2261938_-|hypothetical-protein
MLLFYHGWPDLLGLIYCVAGLIYCEQVAMNAFGNSVGSEINRSQAKAGINRVEMEKNTAKLAQEVSRKIEARVNAQLAASQAAAENRMTKQLATDTAGKLAAQNQAIESSNEADVERMQNGRQSIAEKANVTSAELKADLAALTERHEAQMFKVKETLANAKMLLGEGTEISLTDVPVPNDVVPRGPGPWVDGYVFPDGGENKTTDVTSTASQQNWLEKINQSWVDLENISPYVNEAIGRQSTPGAIFNVVTGLQEAVSAYSGQSVVSSKGKFGVFGYNQSNVSYALKKPAGTGFVYGTIDPTAGKNGKPVVSMGYAANNSQGKHQMWKAANVLTHAPSNLARAAASGGLWGAPLAVVGTTFQYAIDDNKHFASTEFAKDAGLDVIKGVSSGVVASSAGILTTIAVSAAVGAAGGTVIPVVGNVIGFLVGTAAGIYAAYHVEDVYKEAGWR
>NC_007954.1|WP_011496358.1|2259884_2260592_-|hypothetical-protein
MALINSEVKKGVYLSSGVSVMALFFVGIVMIYPPLLDNVEPLLFCFLKTWWLLVALGGLCFIFNNRLNVGYLIWTNIITLFALSYNVLMINIVVSFYGIAEWAYSISMLALVFFSIYQLVIRFKSGGYIESTKKQRVIPGTFYFHPDKHVSLSLNGGRFDSFYDWAGKATAGLVGLSGGLGAVIQGTPMLGGFYVIALSIFSLLFSWFLFKVFLPDLIFCIFAGLDGINKDSHNK
>NC_007954.1|WP_083759649.1|2256322_2259184_-|PAS-domain-S-box-protein
MTTDLHGIIQLFNMGAQQMLGYCSDEVCNRLSMAVITLNEELVARAAALSTEFGDNIAPGFEALVFKAKHDLDDINPLTLIRKNGSRFSAMVSVTSLRDATAAVIGYLLIGTDNSARKEADDKLWQASQYARSLLEASLDPLVTINLSGKITDVNEASIKATGLDREALIGTDFSHYFTDPHEANKGYREAFSNGSVTDYPLTIRHRNGRLIDVLYNASVYRDHKGQVLGLFAAARDITARKRADEALLKAGALQNAIFNSANFSSIATDAKGVIQIFNVGAERMLGYAAIDVINKLTPADISEPQEIVIRARALSHELDTPITPGFDALVFKARRGIEDIYELTYIRKDGSRFPAIVSVTALRDAHNNIIGYLLIGTDNTARKRAEEALLKAGALQRAIFNSANFSSIATDAKGVIQIFNVGAERMLGYTAAEVMDKITPADISDPKEMVLRAAQLSKELETSIAPGFEALVFKASRGIEDIYQLTYIRKDGSRFPAVVSVTALRDAYNVIIGFLLIGTDNTARIQVEEEREQLTATLQDKNAELESSKAIAEKANRAKSEFLSSMSHELRTPLNAILGFAQLLEKGQPTLTHTQEVRIQQIIKAGWYLLSLINEILDLAVIESGRLSLSRESVLLIDVINESKAMVEPQALKREIRLNFLPFSHALHANADHTRLKQVLINLLTNAIKYNRQHGTITVECTEVKAIDKLQDRIRITIKDNGYGLSEANISQLFQPFNRLGQESGSQEGTGIGLVVTKQLVELMGGTIGVKSQVGVGSEFWIELARDLTPNLVNNSNVPAELMPQISAEESKFSLLYVEDNPANLLLVQQIICDLPNVTMLSAREGHQGIALARVKQPDVILMDINLPGISGIEALVILKNDPLTAHIPVLAISANAMPRDIEKGLACGFLRYLTKPIRISEFIEALNFARANSTFTNGNNEPADNDITLSE
>NC_007954.1|WP_011496356.1|2255351_2256263_-|response-regulator
MISEQDIHQAHILIVDDQQANVLLLQDMLTETGYTRIDSTMDPLTVVDLHRSNDYDLILLDLQMPLMDGFEVMKQLKQLAINDYLPILVITAQPDHKLRALTAGAKDFIAKPFDIIEVNTRIRNMLEVRLLYKKLENYNQQLEQTVQERTLELKDSEARYRSLIELASDWYWEQDEQGTFTRFLGPVQQILGFDSEAFPDGNPVGYEEAAECTGSLTSMEPSTAKAKGKSSGWNEAQRTELQTMIVARKPFLDYLLSRVNVDGTQQQYLVSGEPMFNQSARFIGYRGFGVELTTAAVFHNVSR
>NC_007954.1|WP_049762999.1|2254524_2255340_-|Crp/Fnr-family-transcriptional-regulator
MKPADVSQRQSTSVLHSSSHSPSQNHLLAALPQVELESFSDHLELVPMPLGEFLYEPGSGLEYVYFPTTCIVSLHYVLSSGATAETAGVGNEGVVGVSLFMGGNTTASSAVVQTAGYGYRLNKKILMREFDRSGLLQRVLLRYTQALMTQMSQTAVCNRHHSLEQQFCRWLLLTLDRMPTNELVMTHELVASMLGVYREGISLAAGKLQQAGVISYRRGHISVLDRAKLELKSCECYQVVKTELDRLLSDGLLADAKFIKTKTDTQTSKTQ
>NC_007954.1|WP_011496354.1|2252859_2254308_-|DUF3494-domain-containing-protein
MKVNHRIDSRSLWMTSILLTTLMAGCNSDNNEPAQSTPIIISSNIADLTLDVATNSQISVTFSEAMDTATINEVNFSVATGNEAPIMATVSLDNASNTAILTPSNDFTATTLYTAKISREVKSALGIPLANEQVWSFTTAAAPDTTAPSVKATYPLNTEVNFAINRSITAEMSEFLAPNSVNTSNFTLSNGITLVTGTINYSNTTVTFLPDTDLETNTIYTATLTTGITDLAIPANALAESYVWSFTTGLDAAAGPYFVNLRSAGNMAILSKSGITNVPTSNITGNIGASPITAASMDTVFCSDITGIVYGADAAYTGSGDSSCFAGTAPDNTLVANAVLDMGTAYADAAGRTTPDFTELYAGDLSSQTLSAGLYKWGTDVLVSTDVTLNGGANDVWIFQVAGDVLMADGSSIYLTGGAQAKNVFWQVGGGTGAVIGTTAQFEGIVLAKKGITVNTGASVNGRLLAQTAVTLDQNTITQPTQ
>NC_007954.1|WP_011496353.1|2250616_2252404_-|DUF3494-domain-containing-protein
MNTTHTKISRSLWLTTLLMSTLLFGCRNNDDTPPAPEPLPPVVTIPTVTSVTPVDMATQVLINTSVSANFSEAMDAATINLQSVQLTLGAQPVAGAVSLDASSKTAVFTPLTSLASSTAYTMTITSAAKSAAGQALAADVVWSFTSGKSTPTITLTNPLDAATEVAINHNLVATFSEPMDVLTIDTTSFTLSAPNAVPVIGSVSLDTDSNSAIFIPNSDFNPSTVYTASITTAAMSAEGMPLSNDYIWRFTTAVMTDVVAPTVIETDPLNTAIDFPLNRNIVAKFSEAIAPASINNTSFTVTDGVNLVAGKLSYAGTSITFNPTEDLAASTLYTAKLTTAITDLATPANPLASDYVWSFTTSAVAAKGPAAVDLRTAVNFVILTKTGTTNVPTSAITGNMGASPITAAAMDNVFCHEITGIIYGSNAAYTGSGDVSCFKGAAPDNTLVANAVLDMGTAYNDAAGRTLPDFTELHAGDISGRTLTPGLYKWSTGVLISTDVTLTGAANDVWIFQISGDITQAPASRVILEGGAQAKNIFWQVEGGTGVTIGTTAHFEGVVLAEKVIIVNTGASVIGRLLAHTAVTLDQNTVTQPAP
>NC_007954.1|WP_011496352.1|2248891_2250421_+|aminodeoxychorismate-synthase-component-I
MRGNIQLAVKKLNWQITTHALFSHVSHQPWAILLDSGVSSQAEPKSTGLPLADTQAGSNHLDAKFDIIVFDPIATLVTQGTQSHFCVLDKRIKQAFNNETNESNPLSFLNSLNERLYPHRFDSTLPFSGGAVGSFSYDLGRQLETLPDIAMNDIHLSEINIGFYDFCLIYSHQEKSWYATHYLGSAALDAAIENIHLKITKTTSQPGSLHGALQDALLSNAPLPFKLTSDWQCQLSQAQYNQKFNRVQQYLLSGDCYQINLTQRFSAGYQGDEWQAYQALSKANCAPFSAFIRLENHSLLSISPERFIKLEGNSISTKPIKGTLPRGKTLEEDKLNAFRLQASEKDRAENVMIVDLLRNDIGKVAKAGSVAVPSLFAIESFPAVHHLVSTVTATLKPNYTATDLLQAAFPGGSITGAPKIRAMEIIEELEPSRRSLYCGSIGYISQDGKMDTSITIRTLVAERVDNTGRDNPQIYCWAGGGIVADSNVEAEYQESFDKVSKILPILSSL
>NC_007954.1|WP_011496363.1|2279500_2280901_-|hypothetical-protein
MKLKTLLIAPALCMMVTSAIASEFGAYYSFEGQGNGFKDISSNDNNGYFLNSAEGTYTMSGRNGLALEKDVLVVGTMPSHKKDMPITVSAWVRTSELQGVHPLVSKLDAIGNQGFSITVSPQGLTFSLMDQALAGITVSTSGLPSLTSWTHVAVTYSGSGKASGVKVYVNGLEQTTTTLADNLALQTNTFAPLYIGGSIREPAPFPGAIDEVLIAPTAYSIGQIGCLATFGSDCASAIGLGPRGEQGAQGPKGPAGIMGEAGPRGLQGATGDQGAMGPAGEAGPQGPRGDIGPIGNQGVKGANGANGSDGVNGLAGATGAKGPQGRVGATGPQGDIGATGPSGPKGVTGLRGEQGDTGPRGDAGAQGPVGARGSTGATGANGRRGIDGVIGDQGNPGAQGSPGSKGDNSTVRGDTGAKGLAATEFYSSADLHSLRTQLKGDTGAVGPTGPQGFVGRCICSGRRCNL
>NC_007954.1|WP_011496364.1|2280897_2282376_-|hypothetical-protein
MKRIFHSLTTVALLGLSSASAVASNWDAHWSFAGHGNDNFNGAHHGAFPLSGTGSFEFGKLNQALYYDILKVDSLSIQKAAEPFSLSFWALRETRDYAETLFSKQQSPFSAGMSVSLDGANAIVVDIRNGQGGSIKIKSQQVWTDMNDWHHLVVTYNGSIQAGGISLYLDNQRLDVDVISDNLTGDIGASDPVVIGADSETSYATFNGAIDEVYLGSRAFNSSDIECLYALRDNCVDPISDEPPVIAPQGPRGFEGPAGPQGLRGATGSQGVKGAKGPIGDPGVKGPQGSQGSKGDLGLKGLTGITGNPGIDGRNGRDGKDGNAGLMGLQGPDGLQGPKGVRGDTGPMGPQGDPGPQGLKGPTGAKGVTGATGDAGPQGYAGAAGVVGADGTQGAKGDKGLTGATGPTGQKGATGQKGGPGDRGPHGVVIKGPKGAEGDPGARGPQGYSRYYQEGFSNFSTELAESSTKELSPVELYKAMKAEQTIQDGAIK
>NC_007954.1|WP_011496365.1|2282375_2284124_-|hypothetical-protein
MKNKIALAMGLIVVGISPPLFADSMKTSYSFNQANGYPGNGEQNSNGNKGYFPLSGNGQFITAGRSGLALAQDVMVVGGLAPFNKDTPLTVSLWIKPTQDAAGGTILSRKHSENGQGFSVAFDFDMNLEFTLVDEFGGSISVATLTPVNVDQMWHHVAVSYKGDANASNMALYIDGQVTELKLSSNSLTGQVETYHPLVIGGSSSYTQALAAEIDEVYLVPQNFNAEQVTCLYQLKTDCAYRPTTGKEGPRGPIGELGEQGDRGATGVSGLAGDVGLKGNAGLPGPVGPQGPKGPQGFTGPTGLAGIDGSDGIDGSDGTNGAPGAQGAVGDSGIQGPQGSKGLQGNVGPKGASGDRGAQGAMGNQGVAGIKGSQGAQGPTGYTGGAGAAGPIGNKGPTGPTGNGGLQGIPGGPGDNGPKGYTGPAGDNIAGYQGDKGATGPEGPRGRQPSESECSGRFMMGSPEPLLKSMASLTPNLAMTVKGEALLEVQPELDGVIDAGFILSKAMYTSETGLVHINLNVLAVENKQEADGFFSALDASDQAVHDFIVDIYTQKNLDNRYAAEINTILAMPSPLKIEKRAQ
>NC_007954.1|WP_011496366.1|2284232_2285378_-|tetratricopeptide-repeat-protein
MDISRKIERLELFLEQDKDNLNLMLDLIYLSLDAGSIDIAENYLYRAQQQHPESSQLIYLSGLISCQRKNFEQGLITFNSLLSAGVRSASILYQAAYCNIQLGNPETALERLIHASELSPETEILYLLARTQYQLKNFELAVSTLTALADSDAKYAPAHSLLSQIYMDIEQWADAQASAAKALALDPNNVTANITIGFITLNSNQYDQAARHFSQALNVNDESCRTHLGLAIIDVFQQRYVEAEQHLLKALSLQNDLLPGINLLGWLYLLTDRFALARDVFDRGVEVDRSYAEMYGGIAIVDILEKDETAARKNVAIALRLDKMSYAGNFAKILLLQNAQRLSQAEKVWKNLISSPIDDTGKTLEQAVIEQIRAYLKVTLH
>NC_007954.1|WP_011496367.1|2285897_2286785_-|IS982-like-element-ISSde7-family-transposase
MDNLVDVFCDVDDFCAVFMPQWKKQCVTDGTRKRQRSSRMSMSEIMTIIILFHTSHHRDFKNYYTGYLARFFKSDFPHLLSYTRFLELMPTAVVPLCSYFSSIRSLPTGIEFVDSTSVKVCHNLRIPRHKTLSGLARRGKGTMGWFYGFKLHLIVNHKGGIVAAKITPANTHDTKPVSGMVVNAMDKLYADKGYISKALASELLEQGVTLVNNVRKNMKKKVLSLWDRAMLSRRFIIETINDQLKNISQIEHSRHRSVHGFMLNMIGGLIAYQLKESKPQLNITDVDFSAISVMA
>NC_007954.1|WP_011496368.1|2287175_2287697_-|DUF1643-domain-containing-protein
MLGVHKHRLATRKLARAVSVMCLNEIECMEHRVISYKNIVDTNAITMDCDSSGDTTYRYSLTVPFNRKGEKSALVVMMNPSKATDKVSDNTINNVLTRIHNECPEVSKVTITNLYPLYETYSDKLENHKVQSQTNFDKMRLLMEQNDFVLLGWGKPSNKSNKALQKLNTMSMP
>NC_007954.1|WP_011496370.1|2288470_2289295_-|AraC-family-transcriptional-regulator
MYISTTMLLDYNPTQGKVADGRAYKTRQPLPPLNRWVQSYWQLTVSKGQFQYHSVPDNCVDWIINLGCFDDNFFIPPFLSSTLFHIDGPASFFGIRFRILGHKGLISLPLGEWGEAGSVKAEDLLPADIVYTVFEAIDNAKSFDKRCYSLSAVILSAITFADVDPRLARYIRYCYENVSSNLDLSDSQSSKFGVSARQLRRLAKQHVGLLPKDFGKVLRFQSALKAMNAPQNNKTYLDYYYDQPHFVREFKRLSGVTPTQFRKMSVLYNHYSSE
>NC_007954.1|WP_011496371.1|2289436_2289787_-|glyoxalase
MKVIRIVSNVAAADTNEANKFYELIFNLKLIMDHGWIKTFTSGEKMEVQISVASEGGSGTPVPDLSIEVDDLDTVLNRVMTKNIKIEYGPVSEPWGVRRFYVRDPFGKLINVLQHV
>NC_007954.1|WP_011496372.1|2289830_2290049_-|DUF4287-domain-containing-protein
MTEDAKIKGPASYFPSIEKKYGHPITHWLNLLAAVNGKKHMEMVAWLKTEHGMGHGHANALVAYYLVSAKNP
>NC_007954.1|WP_011496373.1|2290737_2291088_-|hypothetical-protein
MIKKILGKLSVVVCLSLYISHAYAGPGYIHVSDMSQVHYQLVGDGNVYFRNLNTFNNTATGCCYAFILDTTTPYGKSAWSVILMKMATKAPLSLYVSDYNPPTSGNPATIDHLGNW

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Crispr_ID: NC_007954_3

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_007954_3

4174136-4174243

Unclear

Consensus_repeat	Method
ATTATTGACCCAGTGCGCTTAAGGC	CRISPRCasFinder

1 spacers

The CRISPR arrays of NC_007954_3

>merge|NC_007954|3|4174136-4174243|CRISPRCasFinder
ATTATTGACCCAGTGCGCTTAAGGCTGCTTGTAGCTCAACAGGGTTTGCTCCCTGACAGAGCTTCAAGCAAAAATTGAACACTATTATTGACCCAGTGCGCTTAAGGC

>NC_007954|3|3|4174136-4174243|CRISPRCasFinder
ATTATTGACCCAGTGCGCTTAAGGC	TGCTTGTAGCTCAACAGGGTTTGCTCCCTGACAGAGCTTCAAGCAAAAATTGAACACT
ATTATTGACCCAGTGCGCTTAAGGC

Protein	Signature genes	Signature genes Name	Protein_function
NC_007954.1\|WP_086022114.1\|4179901_4181061_+\|IS3-like-element-ISSde8-family-transposase	unknown	unknown	gnl\|CDD\|222853
NC_007954.1\|WP_011497901.1\|4171186_4172695_-\|insulinase-family-protein	unknown	unknown	gnl\|CDD\|223685
NC_007954.1\|WP_011497898.1\|4167941_4169117_-\|nitrite-reductase,-copper-containing	unknown	unknown	gnl\|CDD\|131429
NC_007954.1\|WP_011497897.1\|4166896_4167853_-\|hypothetical-protein	unknown	unknown	unknown
NC_007954.1\|WP_157599890.1\|4177288_4177579_-\|hypothetical-protein	unknown	unknown	unknown
NC_007954.1\|WP_011497895.1\|4165663_4166143_-\|copper-chaperone-PCu(A)C	unknown	unknown	gnl\|CDD\|377298
NC_007954.1\|WP_011497910.1\|4183824_4184793_+\|LysR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|176109
NC_007954.1\|WP_011497907.1\|4181221_4181677_-\|hypothetical-protein	unknown	unknown	unknown
NC_007954.1\|WP_011497912.1\|4185357_4186068_-\|hypothetical-protein	unknown	unknown	unknown
NC_007954.1\|WP_011497909.1\|4182503_4183712_-\|multidrug-effflux-MFS-transporter	unknown	unknown	gnl\|CDD\|340878
NC_007954.1\|WP_011497894.1\|4164860_4165454_-\|FMN-dependent-NADH-azoreductase	unknown	unknown	gnl\|CDD\|234675
NC_007954.1\|WP_011497911.1\|4184991_4185285_+\|hypothetical-protein	unknown	unknown	unknown
NC_007954.1\|WP_011497900.1\|4170590_4171052_+\|tRNA-(uridine(34)/cytosine(34)/5--carboxymethylaminomethyluridine(34)-2'-O)--methyltransferase-TrmL	unknown	unknown	gnl\|CDD\|349967
NC_007954.1\|WP_011497899.1\|4169388_4170453_-\|PQQ-binding-like-beta-propeller-repeat-protein	unknown	unknown	gnl\|CDD\|238121
NC_007954.1\|WP_041406537.1\|4166216_4166831_-\|redoxin-domain-containing-protein	unknown	unknown	gnl\|CDD\|239266
NC_007954.1\|WP_157599891.1\|4177680_4177845_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|239805
NC_007954.1\|WP_011497902.1\|4172694_4174020_-\|insulinase-family-protein	unknown	unknown	gnl\|CDD\|223685
NC_007954.1\|WP_157599889.1\|4176395_4177187_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|293786
NC_007954.1\|WP_041405892.1\|4181704_4182391_-\|DTW-domain-containing-protein	unknown	unknown	gnl\|CDD\|377168
NC_007954.1\|WP_011497893.1\|4163851_4164778_+\|DUF3014-domain-containing-protein	unknown	unknown	gnl\|CDD\|378600

Protein	Function_ID	Function_description	E-value
NC_007954.1\|WP_086022114.1\|4179901_4181061_+\|IS3-like-element-ISSde8-family-transposase	gnl\|CDD\|222853	PHA02517, PHA02517, putative transposase OrfB; Reviewed.	1.25276e-58
NC_007954.1\|WP_011497901.1\|4171186_4172695_-\|insulinase-family-protein	gnl\|CDD\|223685	COG0612, PqqL, Predicted Zn-dependent peptidases [General function prediction only].	4.13351e-72
NC_007954.1\|WP_011497898.1\|4167941_4169117_-\|nitrite-reductase,-copper-containing	gnl\|CDD\|131429	TIGR02376, Copper-containing_nitrite_reductase, nitrite reductase, copper-containing. This family consists of copper-type nitrite reductase. It reduces nitrite to nitric oxide, the first step in denitrification. [Central intermediary metabolism, Nitrogen metabolism].	9.20164e-161
NC_007954.1\|WP_011497895.1\|4165663_4166143_-\|copper-chaperone-PCu(A)C	gnl\|CDD\|377298	pfam04314, PCuAC, Copper chaperone PCu(A)C. PCu(A)C is a periplasmic copper chaperone. Its role may be to capture and transfer copper to two other copper chaperones, PrrC and Cox11, which in turn deliver Cu(I) to cytochrome c oxidase.	9.13237e-34
NC_007954.1\|WP_011497910.1\|4183824_4184793_+\|LysR-family-transcriptional-regulator	gnl\|CDD\|176109	cd08417, PBP2_Nitroaromatics_like, The C-terminal substrate binding domain of LysR-type transcriptional regulators that involved in the catabolism of nitroaromatic/naphthalene compounds and that of related regulators; contains the type 2 periplasmic binding fold. This CD includes the C-terminal substrate binding domain of LysR-type transcriptional regulators involved in the catabolism of dinitrotoluene and similar compounds, such as DntR, NahR, and LinR. The transcription of the genes encoding enzymes involved in such degradation is regulated and expression of these enzymes is enhanced by inducers, which are either an intermediate in the metabolic pathway or compounds to be degraded. Also included are related LysR-type regulators clustered together in phylogenetic trees, including NodD, ToxR, LeuO, SyrM, TdcA, and PnbR. This substrate-binding domain shows significant homology to the type 2 periplasmic binding proteins (PBP2), which are responsible for the uptake of a variety of substrates such as phosphate, sulfate, polysaccharides, lysine/arginine/ornithine, and histidine. The PBP2 bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap. After binding their specific ligand with high affinity, they can interact with a cognate membrane transport complex comprised of two integral membrane domains and two cytoplasmically located ATPase domains. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis.	1.6808e-50
NC_007954.1\|WP_011497909.1\|4182503_4183712_-\|multidrug-effflux-MFS-transporter	gnl\|CDD\|340878	cd17320, MFS_MdfA_MDR_like, Multidrug transporter MdfA and similar multidrug resistance (MDR) transporters of the Major Facilitator Superfamily. This family is composed of bacterial multidrug resistance (MDR) transporters including several proteins from Escherichia coli such as MdfA (also called chloramphenicol resistance pump Cmr), EmrD, MdtM, MdtL, bicyclomycin resistance protein (also called sulfonamide resistance protein), and the uncharacterized inner membrane transport protein YdhC. EmrD is a proton-dependent secondary transporter, first identified as an efflux pump for uncouplers of oxidative phosphorylation. It expels a range of drug molecules and amphipathic compounds across the inner membrane of E. coli. Similarly, MdfA is a secondary multidrug transporter that exports a broad spectrum of structurally and electrically dissimilar toxic compounds. These MDR transporters are drug/H+ antiporters (DHA) belonging to the Major Facilitator Superfamily (MFS) of membrane transport proteins, which are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	4.30293e-90
NC_007954.1\|WP_011497894.1\|4164860_4165454_-\|FMN-dependent-NADH-azoreductase	gnl\|CDD\|234675	PRK00170, PRK00170, azoreductase; Reviewed.	1.35259e-115
NC_007954.1\|WP_011497900.1\|4170590_4171052_+\|tRNA-(uridine(34)/cytosine(34)/5--carboxymethylaminomethyluridine(34)-2'-O)--methyltransferase-TrmL	gnl\|CDD\|349967	cd18094, SpoU-like_TrmL, SAM-dependent tRNA methylase related to TrmL. tRNA (Um34/Cm34) methyltransferase TrmL catalyzes the methyl transfer from S-adenosyl-L-methionine (AdoMet) to the 2'-OH at position 34 in both tRNA(Leu)(CmAA) and tRNA(Leu)(cmnm5UmAA). It is part of the SpoU family of MTases, a subfamily of the SPOUT methyltransferase superfamily. The SPOUT methyltransferase superfamily is a large class of S-adenosyl-L-methionine (AdoMet or SAM)-dependent RNA MTases which are structurally characterized by a deep trefoil knot.	2.22584e-86
NC_007954.1\|WP_011497899.1\|4169388_4170453_-\|PQQ-binding-like-beta-propeller-repeat-protein	gnl\|CDD\|238121	cd00200, WD40, WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from its N-terminus and the WD dipeptide at its C-terminus and is 40 residues long, hence the name WD40; between GH and WD lies a conserved core; serves as a stable propeller-like platform to which proteins can bind either stably or reversibly; forms a propeller-like structure with several blades where each blade is composed of a four-stranded anti-parallel b-sheet; instances with few detectable copies are hypothesized to form larger structures by dimerization; each WD40 sequence repeat forms the first three strands of one blade and the last strand in the next blade; the last C-terminal WD40 repeat completes the blade structure of the first WD40 repeat to create the closed ring propeller-structure; residues on the top and bottom surface of the propeller are proposed to coordinate interactions with other proteins and/or small ligands; 7 copies of the repeat are present in this alignment.	6.93148e-13
NC_007954.1\|WP_041406537.1\|4166216_4166831_-\|redoxin-domain-containing-protein	gnl\|CDD\|239266	cd02968, SCO, SCO (an acronym for Synthesis of Cytochrome c Oxidase) family; composed of proteins similar to Sco1, a membrane-anchored protein possessing a soluble domain with a TRX fold. Members of this family are required for the proper assembly of cytochrome c oxidase (COX). They contain a metal binding motif, typically CXXXC, which is located in a flexible loop. COX, the terminal enzyme in the respiratory chain, is imbedded in the inner mitochondrial membrane of all eukaryotes and in the plasma membrane of some prokaryotes. It is composed of two subunits, COX I and COX II. It has been proposed that Sco1 specifically delivers copper to the CuA site, a dinuclear copper center, of the COX II subunit. Mutations in human Sco1 and Sco2 cause fatal infantile hepatoencephalomyopathy and cardioencephalomyopathy, respectively. Both disorders are associated with severe COX deficiency in affected tissues. More recently, it has been argued that the redox sensitivity of the copper binding properties of Sco1 implies that it participates in signaling events rather than functioning as a chaperone that transfers copper to COX II.	5.29483e-50
NC_007954.1\|WP_157599891.1\|4177680_4177845_-\|hypothetical-protein	gnl\|CDD\|239805	cd04278, ZnMc_MMP, Zinc-dependent metalloprotease, matrix metalloproteinase (MMP) sub-family. MMPs are responsible for a great deal of pericellular proteolysis of extracellular matrix and cell surface molecules, playing crucial roles in morphogenesis, cell fate specification, cell migration, tissue repair, tumorigenesis, gain or loss of tissue-specific functions, and apoptosis. In many instances, they are anchored to cell membranes via trans-membrane domains, and their activity is controlled via TIMPs (tissue inhibitors of metalloproteinases).	0.00040182
NC_007954.1\|WP_011497902.1\|4172694_4174020_-\|insulinase-family-protein	gnl\|CDD\|223685	COG0612, PqqL, Predicted Zn-dependent peptidases [General function prediction only].	4.25523e-95
NC_007954.1\|WP_157599889.1\|4176395_4177187_-\|hypothetical-protein	gnl\|CDD\|293786	sd00045, ANK, ankyrin repeats. Ankyrin repeats are one of the most abundant repeat motifs, and generally function as scaffolds for protein-protein interactions in processes including cell cycle, transcriptional regulation, signal transduction, vesicular trafficking, and inflammatory response. Although predominantly found in eukaryotic proteins, they are also found in some bacterial and viral proteins. Less is known of their physiological roles in prokaryotes. Some bacterial ANK proteins play key roles in microbial pathogenesis by mimicking or manipulating host function(s). The pathogen Providencia alcalifaciens N-formyltransferase ankyrin repeats function in small molecule binding and allosteric control. Ankyrin-repeat proteins have been associated with a number of human diseases.	4.46274e-12
NC_007954.1\|WP_041405892.1\|4181704_4182391_-\|DTW-domain-containing-protein	gnl\|CDD\|377168	pfam03942, DTW, DTW domain. This presumed domain is found in bacterial and eukaryotic proteins. Its function is unknown. The domain contains multiple conserved motifs including a DTXW motif that this domain has been named after.	8.44813e-55
NC_007954.1\|WP_011497893.1\|4163851_4164778_+\|DUF3014-domain-containing-protein	gnl\|CDD\|378600	pfam11219, DUF3014, Protein of unknown function (DUF3014). This family of proteins with unknown function appears to be restricted to Proteobacteria.	1.50886e-77

>NC_007954.1|WP_011497902.1|4172694_4174020_-|insulinase-family-protein
MKRSFTALTLLMGLVASSVAQATTAEDIKSFTLDNGMKIMVLEDASIPNANMYLFWKVGSRNEVPGITGISHFFEHMMFNGSKKYGPKMFDRTMEAAGGANNAYTSEDLTVYTDWFPANALETMFDLEADRIAHLDINPEMVESERGVVASERTTGLENSNWRTLQEALKGVAFSAHPYSWSVIGYESDIAAWTLDDLVQYHKTYYAPNNAIVVVAGDVKFDEVKRLATQYFGPIPAQAPPKAVRTVEPEQKGERRLFVEKASVSTPNVMLAYHVPATSDEDYYALDLLNSILSQGNSSRFYKSLVDKQVALAAETYLPMSFDPNLFYILGVANQGVEAQVLEKAMIAQINLISTEGVSQDELEKVKNIKLMEFYQTMETINGKANTLGTYELYFGSFEKLFNAPEAYNKVTPADIQRVAAKYLVKANRTVGVLAAKEGAE
>NC_007954.1|WP_011497901.1|4171186_4172695_-|insulinase-family-protein
MTTPIKNKTPHPIKVNNKLALSVALACSLGLSGCAATANSDTAKSVASKPLAANVPSATINRFAMPAYETVTLANGLVINLMPQKEVPLISLNAVVRVGAVDDTVSGLAYIASQSLMLGAGKLTKAEIEQKIDFLGASINTSADKEGSYVSANFMAKDVDTLLAIFSDVLQAPSFNSQEFDKLKQREIAGLAQEKESPRAVIGRYFDKLAFGDHAYGKPVSGNSESVAKISVNDLLAFHSSHYLPANTAINVVGDFEPSAMKAKLEAAFGGWQGTKAESNVDLSAGLADFSQSRVLLVDKPDAIETTFLIGGKGISRDNPDYVGLTVVNTILGGRFTSWLNDELRVNAGLTYGARSGFTPYSKAGVFQISTFTKSETTKEAIDLALKTYARLWQKGIDQGTLDSAKAYVKGQFPPKFETSGQLAGLLADMYLYGFDDNFINQFQAKVDGLTLEETQRLVRDYFPQENLQFVLIGNASVIAPIAAQYGEVTQVDIKAMGFDAK
>NC_007954.1|WP_011497900.1|4170590_4171052_+|tRNA-(uridine(34)/cytosine(34)/5--carboxymethylaminomethyluridine(34)-2'-O)--methyltransferase-TrmL
MFHIALYEPEIAPNTGNIIRLCANNGSHLHLIEPLGFDLEEKKLRRAGLDYADLANVTRHKNYDDFLQAMAGKRIMVCTTKGSRPHTELEFAKDDVLLFGPETRGLPMDIINAAPLEQRLRIPMMSSSRSLNLSNSVAIISYEAWRQLGFEGA
>NC_007954.1|WP_011497899.1|4169388_4170453_-|PQQ-binding-like-beta-propeller-repeat-protein
MNMIILQNTLFKPLAKWRYLSINRLGLFTALLLLFLLSGCDKAPPSQTSLSQHRLVEGRLVDGALSKDGLLAVTLSLNGDVNVWDLVSKQAFVTWRKADFNDDIYQLMLSGDKQYLLAASQRQLFLLDVTTGERLLNWQAEAFNPDANISSIHLNYSASQILVGMSDGSINTVDRSSNSLSLFKQHSAEVSAVAFLSSSDQVLSTGHDGELLIWATATGKVHRRFALPHRIMSLAIDSANRRLFAADALDNHFIIDPESASFSSMDALGASVNLQYVERYRYFRRALFVKHGNMLITATSKQDMIGWDSQSGAELVHWRLQAYSASTSVTAMAVNGEGQLVTLSSDGAIELWPL
>NC_007954.1|WP_011497898.1|4167941_4169117_-|nitrite-reductase,-copper-containing
MENKTSTTQSTVNEQRRNFISGSIGAGLVGAGIAAGLVSSSAQGATGKKLDRMANYTADQLERVKQVLVAPPMVPVHEQVAKGKPKVIEVRLEVEEKQIELENGTKAWVCAFNGSVPGPLIVCHQHDYVELTLVNPKTNMLAHNIDLHSATGALGGGELTLVSPGETVTFRFKATKVGTFVYHCAPGGVMIPWHVVMGMNGAIMVLPREGLSDGEGNRLTYDKAYYIGEQDFYIAKDDQGKYKAYDTVMGSMNDTLEVMKTLTPSHVVFNGAVGALTGKNSMTAKLGESVLFIHSQANRDTRPHIIGGHGDYVWNTGSFSDRPARDLETWHIAGGCAGAALYTFLQPGLYAYVNHNLIEAIMKGAAAHIKVEGEWNDDLMTQVSKPSPIKA
>NC_007954.1|WP_011497897.1|4166896_4167853_-|hypothetical-protein
MLRLLALFLVVCISANAYAAELIKDYLINAQVYQWYGDLDASQQWHEKYPNAKVDLKEYAPELIRGQSQGEPLEQAYWQTGAHHILDISPLPESTPGLTQVRVTVEFYPQADNDEPVQGYYLQQLLSFEHQSHSSSPSLNSSFSPRLSKVETEFIEQDDFGSRFIASSDTNLIRGFLYRWTLGLDEPETDNLSLWLSPEAKLALAEAQITSIADYQAYLGGLGLTQSRRAIKNLQIQPVSAAKAISAEQDSIEGRHSRVEYRVEFEYQWSALNGEGEIEMANIGVVIYLHVQQGRVQVKGYQEQYLAPKTDLGAEIRC
>NC_007954.1|WP_041406537.1|4166216_4166831_-|redoxin-domain-containing-protein
MTMLAAVQLYLVLALFGSSVALAQMPVLKGIGGEFSLKSSKGGEVSLSDFKDKVVLMFFGYTNCADICPTTMAHISQMMNKLTPEQRSRVQVLFVSIDSDYDTPKHLNKYLAYFDPSFIGLVDEREKIDYVAKLFHADYIKLANDKVTTEFKKLSLDDEKQEQKGYLYSHSAKIFVMDTHSRVRGFFYAGTAIEDMRQQVISLL
>NC_007954.1|WP_011497895.1|4165663_4166143_-|copper-chaperone-PCu(A)C
MKHAPSFMTLLASASLILGILSSQALAADIMVVDAWSRAMPPTARVLPVYLTLHNHGDSQVSLIKISSKLGAVALHNTVMENDMMRMQAVDKIVVQAKQQIKLAPMGLHAMVTGLTQAVPGEGDVLPLTLSFDNGEQMSINALVRKVAMPEAADKHAHH
>NC_007954.1|WP_011497894.1|4164860_4165454_-|FMN-dependent-NADH-azoreductase
MAKVLVLKSSILGDYSQSSALIGHLMSHWQQQGAQMTVRDLAADPVPVLDGEIATGMRGGDNLSPRQQQVLDLSDELIAELKSHDTLVIAAPMYNFSIPTQLKNWIDLIARAGVTFTYTETGPKGLLEGKRAVVVTTRGGMHKEGASDHIVPYLKTVLGFIGITEVEFVYAEALNMGPDATAQGLLEAKTALDSLTA
>NC_007954.1|WP_011497893.1|4163851_4164778_+|DUF3014-domain-containing-protein
MQVNQEDRISPTTEKPSSGNNTPLIAIAVIALLAVGGYFYISSDSDEMPEQLITPVELPDSIPTTPIEQDPIEEQELAATGIPSSQIEGNNSQELSGTTDQQTANPADAKPVEPLPALAESDDFIESKTLAIANGMKIEPLILKKDMARQFVVFVDNLAQGELVRKASPIKGPDRNFSVSEITNKIFINPDSFHRYDLYANFVAGLNEQELLSTYKELTPLFNEAFEELGYSDVSFDARMQQAMKMVLDAPIIEDPIELKSVTVNYHFAEHNLEALPNAQKFLIRMGPENTRKIKAAVKKLQLLLDNQ
>NC_007954.1|WP_157599889.1|4176395_4177187_-|hypothetical-protein
MLMIQHNLSKYTSIVLLCFISACNASSHQLERSESNYSETVSNKVLIHMDIETMFANSQLRSLAYAAGKGKMSQIDKLLEQGVDVNAKGTNNATVLFWSMRNKKGFEYLLKQGANPNVVFGDGGSVMHWVARKRDCSMLMSALQHGGNPNLKAGMFGGSPAFETITAGKNDGVPNCLKLLLSKDADIDFQDEQGQSVLLAAADLARFDITLYLLKSGANSKLMDNKQRTVRDLVNSYKGAFIKGSVTEEYWLKVDAWLLNSGE
>NC_007954.1|WP_157599890.1|4177288_4177579_-|hypothetical-protein
MLKHIVNFEDLIIKVKGIRLSDVGYERLISVLDKTTSVKDIRIHKAEDITSVFDSIKGVRRVKLFLFNGDNPMMKVEIVITSPKNYDVEHATLVIN
>NC_007954.1|WP_157599891.1|4177680_4177845_-|hypothetical-protein
MISVHCSFTLAHEIGHSIGLMHQWNSTTSLMSYSSMEKNSIYYNQMNNLYEAYR
>NC_007954.1|WP_086022114.1|4179901_4181061_+|IS3-like-element-ISSde8-family-transposase
MTRKSAVHISPLQKLEYAKLMVEQGYTNKQIEDMSGAGKSAVSRWKVQYQAELAGETPENAKALTEDQRRIQLLEAQLKQAMRDNDNLKKGCSFLHSRQSKLKMMREVKKANPEFKVNELCRAFEISCSSFYYKPIPLSINKQSVMQLVEEVFTDSYSTYGKRRIQAELLDLDCRVGVYAISTVMKNLGLRAIRPKKKHYYPNQGEEQVYAPNLLRRQFNPTTYNTHWVGDITYIKLHQGWSYLACVLDLGTKEIVGYALSSQPNAALATAALNNAIQRKRPNTQALMFHSDQGCQYSAKVFRERLKHLGIEQSMSRRGNCWDNAVMERFFRSLKTERLNHLAFINHSAVVSVVEQYIQFYNYKRRHSAIDYKTPHQKYNELKKAA
>NC_007954.1|WP_011497907.1|4181221_4181677_-|hypothetical-protein
MPRIYQQYLRSHLAQRRWALSAIAPLMFCSGLLAQDKPVIKLKAPLNSEQTLEAKADAARDISYKTEQVQLKKARQGDQALQLKAHKILKQQQGNDWQAEQQHKAEQAFRARTSREQGYLEAAQQAATQEKKITAPQEAVEEKPAQLKQQD
>NC_007954.1|WP_041405892.1|4181704_4182391_-|DTW-domain-containing-protein
MSRIYCQGCQYPKNACLCAHLKPMSCLTQVIVMQHPSEVSQSKNTVHLLSLVLPAMRRYVGESSADFEELRQGLDLQHCYLVYPSDKSQSAEQISIALANANDDAASSKCVRGSPANSAPRTAPQTQTKISIILLDGTWRKAYRMLQLNPWLLELPSLHLNFEGQSQYRIRKSSRTDSLSTLEAAAYTIQALEPNVDIEPILKLFDAMVQARLDAMPTQVRARYHDDK
>NC_007954.1|WP_011497909.1|4182503_4183712_-|multidrug-effflux-MFS-transporter
MRRNLLALLMSMVVLSPLAIDIYLPAMPTMAVDYAVSNSEIQSTLVLFLFAMGVGQILIGPLADRFGRRPIALFGIVLYGASSLLAAASVDFYWLQIARVLQGLAACSTSIVVFSAVRDCYSAKESMTMYSYLNGAICVIPALAPTFGGLLALEFGWRSTFMFMALYAVFVLLFVGYRFPETRPLNTDSKGPIYRWARYKPVVANVHFMFYALVCMAAMASILAYVSYSPVWLIGGLGMSELMFSGLFGLNAFVNVTACFAAPLLVSKLGNRNSVILALSLMLSAAVIEAGLQLMFTLDGLLGGLAFMLPMMLLCIGFALLLGPATTMALAGFGERAGTATAMLGFIQMSGAALLTGLIQLTSIPAPYAVALIMGGLSTILLLMMATKGLGHWHQERLQLEH
>NC_007954.1|WP_011497910.1|4183824_4184793_+|LysR-family-transcriptional-regulator
MNLDNLARIDLNLLVILQVLLEEQSVTRAANRLHLSQSALSKSLNRLRDTLDDPLFQRTAHGLKPTAHAVALAQKLPGVLQHLYQLTQPPTFNPNSSHRQFSFSMVESAYETLIPYFIGPLLSNAPHLKLDSYLWTEKSMQDLLQGQIDFGIAGRDIHPQSNFRVEKLPEGLEHKTLFNDFQVCLVRKGHPILTQVTMGQWTQQQYLDMPHVQVRCEGNDWWALDYHLASMNLHRNICTTVPDFYGAASICAHSELIFTLPSSFARHAQQLYALEEIPLPMAFTPMTYVLLWHERNNQEPGHKWMREMIVDSAAKATTKRQS
>NC_007954.1|WP_011497911.1|4184991_4185285_+|hypothetical-protein
MRFNLNELTLKLKALPPLLAVSYCLLGLLGFALLPLILPLVAIAALIATLGLRRFSRHYLPPKMGQTYPKVRLSTLYKSDPHIDKVNATEFDNQPAK
>NC_007954.1|WP_011497912.1|4185357_4186068_-|hypothetical-protein
MSLSAILTEAYNFFRNHVSQLAALTLPLLLIQVVIQLWLGQEMLQADLENPVFGPIHGAAMMALLVTFSILIAALTLYLQLRSEGHDLKPLAIIKASFPFVPPLLLAGVFSGLAILAPVMLFAAFGPFWIIGLVVSFYLFSRLAYVNFMVVVERLTPLQAIKTSFVFSGPLVLKTIAVISLYIPLSLVGGAVAGLAKAGGLPVQLIIEVGVAFLGLFVNVALYRLYMVARTTDKTE

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

1246070 : 1318933

Staphylococcus_phage(21.43%)

integrase,transposase

attL 1302860:1302902|attR 1308893:1308935

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_011495538.1\|1246070_1246958_+\|transposase	IS982-like element ISSde7 family transposase	NA	NA	NA	NA
WP_011495539.1\|1247055_1249143_-	M13 family peptidase	A0A1V0SHG2	Klosneuvirus	1.5e-96	31.3
WP_011495540.1\|1249504_1250194_+	16S rRNA pseudouridine(516) synthase RsuA	NA	NA	NA	NA
WP_011495541.1\|1250908_1252771_+	methyl-accepting chemotaxis protein	A0A2H4J162	uncultured_Caudovirales_phage	1.2e-41	35.8
WP_011495542.1\|1252905_1253565_-	ribose-5-phosphate isomerase RpiA	NA	NA	NA	NA
WP_011495543.1\|1253673_1254489_-	mechanosensitive ion channel	NA	NA	NA	NA
WP_011495544.1\|1254498_1255686_-	ATP-binding protein	NA	NA	NA	NA
WP_011495545.1\|1255973_1256870_+	D-alanyl-D-alanine endopeptidase	NA	NA	NA	NA
WP_011495546.1\|1256951_1258208_-	SGNH/GDSL hydrolase family protein	NA	NA	NA	NA
WP_011495547.1\|1258303_1259335_-	hypothetical protein	NA	NA	NA	NA
WP_011495548.1\|1259338_1260256_-	triacylglycerol lipase	NA	NA	NA	NA
WP_011495549.1\|1260770_1262210_+	hypothetical protein	NA	NA	NA	NA
WP_011495550.1\|1262287_1263211_-	LysR family transcriptional regulator	NA	NA	NA	NA
WP_041405694.1\|1263668_1264064_+	DUF2391 family protein	NA	NA	NA	NA
WP_011495552.1\|1264171_1264963_+	PhzF family phenazine biosynthesis protein	NA	NA	NA	NA
WP_157599836.1\|1264989_1265316_+	hypothetical protein	NA	NA	NA	NA
WP_011495554.1\|1265399_1266650_-	c-type cytochrome	NA	NA	NA	NA
WP_011495555.1\|1266646_1267183_-	(2Fe-2S)-binding protein	NA	NA	NA	NA
WP_011495556.1\|1267179_1270053_-	xanthine dehydrogenase family protein molybdopterin-binding subunit	NA	NA	NA	NA
WP_011495557.1\|1270504_1270993_+	N-acetyltransferase	NA	NA	NA	NA
WP_011495558.1\|1271111_1271810_+	alpha/beta hydrolase	NA	NA	NA	NA
WP_011495559.1\|1272107_1273316_+	potassium/proton antiporter	NA	NA	NA	NA
WP_041405695.1\|1273530_1274016_+	cupin domain-containing protein	NA	NA	NA	NA
WP_011495561.1\|1274390_1275464_+	hypothetical protein	A0A1S5SAB0	Streptococcus_phage	1.3e-67	41.6
WP_011495562.1\|1275805_1276708_+	hypothetical protein	NA	NA	NA	NA
WP_011495563.1\|1276872_1277625_+	hypothetical protein	NA	NA	NA	NA
WP_041405696.1\|1277977_1278181_+	hypothetical protein	NA	NA	NA	NA
WP_011495564.1\|1278497_1279679_+	SEC-C domain-containing protein	NA	NA	NA	NA
WP_011495565.1\|1280182_1283908_-	methionine synthase	A0A140XBC7	Dickeya_phage	3.0e-15	59.0
WP_011495566.1\|1284404_1285328_+	ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	1.8e-14	29.8
WP_041406094.1\|1285327_1286374_+	iron ABC transporter permease	NA	NA	NA	NA
WP_011495568.1\|1286600_1287389_+	adenosylcobinamide-GDP ribazoletransferase	NA	NA	NA	NA
WP_041406095.1\|1287619_1288231_+	cob(I)yrinic acid a,c-diamide adenosyltransferase	NA	NA	NA	NA
WP_041406096.1\|1288468_1289215_+	hypothetical protein	NA	NA	NA	NA
WP_011495571.1\|1289459_1289762_+	DUF1330 domain-containing protein	NA	NA	NA	NA
WP_011495572.1\|1289821_1290790_+	MBL fold metallo-hydrolase	NA	NA	NA	NA
WP_011495573.1\|1291291_1292341_+	hypothetical protein	NA	NA	NA	NA
WP_011495574.1\|1292347_1293406_+	hypothetical protein	NA	NA	NA	NA
WP_011495575.1\|1293639_1294059_+	hypothetical protein	NA	NA	NA	NA
WP_157599917.1\|1294074_1294218_-	hypothetical protein	NA	NA	NA	NA
WP_011495578.1\|1295949_1297956_+	hypothetical protein	NA	NA	NA	NA
WP_041405697.1\|1298219_1298867_+	NAD(P)H-binding protein	NA	NA	NA	NA
WP_011495580.1\|1299207_1300167_-\|integrase	integron integrase	A0A1P8DJJ6	Virus_Rctr41k	8.4e-55	39.6
WP_157599837.1\|1300857_1301358_+	GyrI-like domain-containing protein	NA	NA	NA	NA
WP_011495582.1\|1301741_1302317_+	sel1 repeat family protein	NA	NA	NA	NA
1302860:1302902	attL	NA	NA	NA	NA
WP_157599838.1\|1302969_1303344_+	hypothetical protein	NA	NA	NA	NA
WP_011495583.1\|1303351_1304323_-\|transposase	IS110-like element ISSde13 family transposase	NA	NA	NA	NA
WP_041405698.1\|1304646_1305207_+	hypothetical protein	NA	NA	NA	NA
WP_011495585.1\|1305485_1306574_-\|transposase	IS91-like element ISSde12 family transposase	NA	NA	NA	NA
WP_011495586.1\|1306570_1307461_-\|integrase	tyrosine-type recombinase/integrase	S5W9T9	Leptospira_phage	5.5e-24	29.9
WP_086022097.1\|1309902_1311061_+\|transposase	IS3-like element ISSde8 family transposase	U5P429	Shigella_phage	6.6e-38	38.3
1308893:1308935	attR	NA	NA	NA	NA
WP_011495588.1\|1311454_1313122_-	energy-dependent translational throttle protein EttA	A0A1V0SKJ1	Klosneuvirus	1.1e-38	27.6
WP_011495589.1\|1313311_1314565_+	serine hydroxymethyltransferase	A0A240F3L3	Aeromonas_phage	9.2e-102	53.4
WP_011495590.1\|1314678_1315128_+	transcriptional regulator NrdR	NA	NA	NA	NA
WP_011495591.1\|1315260_1316397_+	bifunctional diaminohydroxyphosphoribosylaminopyrimidine deaminase/5-amino-6-(5-phosphoribosylamino)uracil reductase RibD	A0A1V0SE20	Indivirus	6.9e-48	36.2
WP_011495592.1\|1316499_1317153_+	riboflavin synthase	A0A2H4PQS5	Staphylococcus_phage	2.8e-25	32.5
WP_011495593.1\|1317228_1318332_+	bifunctional 3,4-dihydroxy-2-butanone-4-phosphate synthase/GTP cyclohydrolase II	A0A2H4PQS2	Staphylococcus_phage	1.9e-66	39.5
WP_011495594.1\|1318453_1318933_+	6,7-dimethyl-8-ribityllumazine synthase	A0A2H4PQS3	Staphylococcus_phage	1.5e-28	45.7

DBSCAN-SWA_2

3187471 : 3194872

Enterobacteria_phage(33.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_011497086.1\|3187471_3188572_-	CDP-glucose 4,6-dehydratase	A0A222YY99	Synechococcus_phage	5.0e-11	30.2
WP_011497087.1\|3188576_3189347_-	glucose-1-phosphate cytidylyltransferase	NA	NA	NA	NA
WP_011497088.1\|3189381_3190485_-	DegT/DnrJ/EryC1/StrS family aminotransferase	E5ES42	Bathycoccus_sp._RCC1105_virus	1.7e-38	29.7
WP_011497089.1\|3190484_3191399_-	isomerase	NA	NA	NA	NA
WP_011497090.1\|3191412_3191952_-	dTDP-4-dehydrorhamnose 3,5-epimerase	I7HJC4	Enterobacteria_phage	7.1e-51	56.4
WP_011497091.1\|3191952_3192828_-	dTDP-4-dehydrorhamnose reductase	A0A291LA50	Escherichia_phage	1.2e-39	36.4
WP_011497092.1\|3192829_3193699_-	glucose-1-phosphate thymidylyltransferase RfbA	K7QKA7	Escherichia_phage	1.0e-107	68.2
WP_011497093.1\|3193783_3194872_-	dTDP-glucose 4,6-dehydratase	I7HTA3	Enterobacteria_phage	2.4e-98	52.7

DBSCAN-SWA_3

3536803 : 3609567

Streptococcus_phage(14.29%)

protease,transposase,tRNA,tail

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_011497383.1\|3536803_3537760_+\|tRNA	tRNA-modifying protein YgfZ	NA	NA	NA	NA
WP_011497384.1\|3538186_3538852_-	hypothetical protein	NA	NA	NA	NA
WP_011497385.1\|3539566_3541660_-	elongation factor G	E4ZFJ7	Streptococcus_phage	5.9e-61	28.2
WP_011497386.1\|3541965_3542844_-	GGDEF domain-containing protein	G3MA91	Bacillus_virus	8.6e-14	28.8
WP_011495916.1\|3542840_3544043_-\|transposase	IS4-like element ISSde1 family transposase	A0A0F7LAS3	uncultured_marine_virus	2.1e-111	49.7
WP_083759694.1\|3544141_3544750_-	transporter substrate-binding domain-containing protein	NA	NA	NA	NA
WP_011497388.1\|3545050_3549604_-	ATP-grasp domain-containing protein	NA	NA	NA	NA
WP_011497389.1\|3549728_3550640_+	LysR family transcriptional regulator	NA	NA	NA	NA
WP_011497390.1\|3550704_3551436_-	hypothetical protein	NA	NA	NA	NA
WP_157599871.1\|3551647_3552115_-	hypothetical protein	NA	NA	NA	NA
WP_011497392.1\|3552074_3552788_-	hypothetical protein	NA	NA	NA	NA
WP_011497393.1\|3552797_3553481_-	C39 family peptidase	NA	NA	NA	NA
WP_011497394.1\|3553534_3554602_-	hypothetical protein	NA	NA	NA	NA
WP_041405847.1\|3554628_3555261_-	hypothetical protein	NA	NA	NA	NA
WP_011497396.1\|3555498_3556836_-	sigma-54-dependent Fis family transcriptional regulator	NA	NA	NA	NA
WP_011497397.1\|3557252_3558452_+	hypothetical protein	NA	NA	NA	NA
WP_049763060.1\|3558530_3559142_+\|protease	SprT family zinc-dependent metalloprotease	A0A125ST76	Ralstonia_phage	6.6e-05	44.8
WP_083759695.1\|3559346_3559967_+	deoxyribonuclease	NA	NA	NA	NA
WP_011497400.1\|3559980_3560715_+	16S rRNA (uracil(1498)-N(3))-methyltransferase	NA	NA	NA	NA
WP_011497401.1\|3560750_3561710_+	glutathione synthase	NA	NA	NA	NA
WP_011497402.1\|3561712_3563098_+	alkaline phosphatase	NA	NA	NA	NA
WP_011497403.1\|3563214_3564252_+	methyltransferase	NA	NA	NA	NA
WP_011497404.1\|3564539_3566207_+	DUF342 domain-containing protein	NA	NA	NA	NA
WP_083759659.1\|3566268_3566700_+	DUF4144 domain-containing protein	NA	NA	NA	NA
WP_011497406.1\|3566789_3567971_+\|protease	site-2 protease family protein	NA	NA	NA	NA
WP_011497407.1\|3568144_3569032_+\|transposase	IS982 family transposase	NA	NA	NA	NA
WP_011497408.1\|3569044_3570394_-	lysine-sensitive aspartokinase 3	NA	NA	NA	NA
WP_011497409.1\|3570823_3571261_-	DUF3293 domain-containing protein	NA	NA	NA	NA
WP_011497410.1\|3571926_3572643_+	two-component system response regulator ArcA	NA	NA	NA	NA
WP_157599951.1\|3572761_3575026_-	prolyl oligopeptidase family serine peptidase	NA	NA	NA	NA
WP_011497412.1\|3575610_3576603_+	class 1 fructose-bisphosphatase	A0A1V0SKX4	Klosneuvirus	2.4e-44	38.1
WP_011497413.1\|3576693_3577947_-	dicarboxylate/amino acid:cation symporter	NA	NA	NA	NA
WP_011497414.1\|3578129_3579038_-	hypothetical protein	NA	NA	NA	NA
WP_011497415.1\|3579025_3580246_-	hypothetical protein	NA	NA	NA	NA
WP_011497416.1\|3580242_3580890_-	hypothetical protein	NA	NA	NA	NA
WP_011497417.1\|3580889_3584579_-	ATP-binding protein	NA	NA	NA	NA
WP_041406440.1\|3585018_3585447_-	DUF4157 domain-containing protein	NA	NA	NA	NA
WP_011497419.1\|3585778_3586231_-\|tail	phage tail protein	NA	NA	NA	NA
WP_011497420.1\|3586624_3587653_-	hypothetical protein	NA	NA	NA	NA
WP_011497421.1\|3587801_3590555_-	hypothetical protein	NA	NA	NA	NA
WP_011497422.1\|3590551_3591988_-	ATP-binding protein	A0A1C9EGA6	Acidianus_two-tailed_virus	2.4e-13	37.8
WP_011497423.1\|3592089_3597723_-	hypothetical protein	NA	NA	NA	NA
WP_011497424.1\|3597712_3600433_-	hypothetical protein	NA	NA	NA	NA
WP_011497425.1\|3600422_3601340_-	hypothetical protein	NA	NA	NA	NA
WP_011497426.1\|3601332_3605574_-	hypothetical protein	NA	NA	NA	NA
WP_041406443.1\|3605563_3605980_-	GPW/gp25 family protein	D6PHT9	uncultured_phage	1.1e-06	28.2
WP_011497428.1\|3606134_3606434_-	type VI secretion protein	NA	NA	NA	NA
WP_041405848.1\|3606444_3608235_-	type VI secretion system tip protein VgrG	NA	NA	NA	NA
WP_011497430.1\|3608269_3608911_-	peptidoglycan-binding protein	NA	NA	NA	NA
WP_157599872.1\|3608920_3609091_-	hypothetical protein	NA	NA	NA	NA
WP_011497431.1\|3609093_3609567_-\|tail	phage tail protein	NA	NA	NA	NA

DBSCAN-SWA_4

3831636 : 3891614

Vibrio_phage(25.0%)

integrase,terminase,protease,tail,tRNA,portal

attL 3862220:3862235|attR 3887400:3887415

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_011497618.1\|3831636_3832095_-\|protease	ClpXP protease specificity-enhancing factor	NA	NA	NA	NA
WP_011497619.1\|3832094_3832724_-	stringent starvation protein A	NA	NA	NA	NA
WP_011497620.1\|3832818_3833514_-	cytochrome c1	NA	NA	NA	NA
WP_011497621.1\|3833513_3834728_-	cytochrome bc complex cytochrome b subunit	NA	NA	NA	NA
WP_011497622.1\|3834727_3835318_-	ubiquinol-cytochrome c reductase iron-sulfur subunit	NA	NA	NA	NA
WP_011497623.1\|3835769_3836666_-\|protease	protease modulator HflC	NA	NA	NA	NA
WP_011497624.1\|3836669_3837830_-\|protease	FtsH protease activity modulator HflK	NA	NA	NA	NA
WP_011497625.1\|3837862_3839170_-	GTPase HflX	NA	NA	NA	NA
WP_011497626.1\|3839193_3839463_-	RNA chaperone Hfq	NA	NA	NA	NA
WP_041405866.1\|3839546_3840473_-\|tRNA	tRNA (adenosine(37)-N6)-dimethylallyltransferase MiaA	NA	NA	NA	NA
WP_011497628.1\|3840465_3842463_-	DNA mismatch repair endonuclease MutL	A0A1B2LRQ5	Wolbachia_phage	1.1e-56	40.0
WP_011497629.1\|3842469_3843837_-	AMIN domain-containing protein	A0A067ZJB6	Vibrio_phage	7.6e-17	29.3
WP_041405868.1\|3843839_3844298_-\|tRNA	tRNA (adenosine(37)-N6)-threonylcarbamoyltransferase complex ATPase subunit type 1 TsaE	NA	NA	NA	NA
WP_011497631.1\|3844442_3844898_-	hypothetical protein	NA	NA	NA	NA
WP_011497632.1\|3845153_3845876_+	hypothetical protein	NA	NA	NA	NA
WP_011497633.1\|3847171_3847717_-	oligoribonuclease	Q8B5Y0	Diachasmimorpha_longicaudata_entomopoxvirus	2.3e-25	38.7
WP_011497634.1\|3847825_3848887_+	small ribosomal subunit biogenesis GTPase RsgA	NA	NA	NA	NA
WP_011497635.1\|3848919_3849789_+	phosphatidylserine decarboxylase	NA	NA	NA	NA
WP_011497636.1\|3849952_3850675_+	glycerophosphodiester phosphodiesterase	A0A0D3MUY6	Staphylococcus_phage	6.8e-17	28.5
WP_011497637.1\|3850750_3851086_-	DUF3392 domain-containing protein	NA	NA	NA	NA
WP_011497638.1\|3851273_3851465_+	(2Fe-2S)-binding protein	NA	NA	NA	NA
WP_011497639.1\|3851688_3854001_-	DNA topoisomerase IV subunit A	G3M9Z5	Bacillus_virus	7.6e-86	36.1
WP_011497640.1\|3853993_3855154_-	L-sorbosone dehydrogenase	NA	NA	NA	NA
WP_011497641.1\|3855290_3857177_-	DNA topoisomerase IV subunit B	G3M9Z3	Bacillus_virus	5.8e-92	35.1
WP_011497642.1\|3857222_3857798_-	esterase	NA	NA	NA	NA
WP_011497643.1\|3857919_3858759_-	3',5'-cyclic-AMP phosphodiesterase	NA	NA	NA	NA
WP_041406483.1\|3858786_3859230_-	DUF1249 domain-containing protein	NA	NA	NA	NA
WP_011497645.1\|3859297_3859921_-	ADP-ribose diphosphatase	NA	NA	NA	NA
WP_011497646.1\|3860277_3861576_+	outer membrane channel protein TolC	NA	NA	NA	NA
WP_011497647.1\|3861877_3862621_-	TIGR04219 family outer membrane beta-barrel protein	NA	NA	NA	NA
3862220:3862235	attL	NA	NA	NA	NA
WP_011497648.1\|3862686_3863658_-	DUF2333 family protein	NA	NA	NA	NA
WP_011497649.1\|3863670_3864162_-	copper chaperone PCu(A)C	NA	NA	NA	NA
WP_011497650.1\|3864197_3864935_+	enoyl-CoA hydratase	NA	NA	NA	NA
WP_011497651.1\|3865013_3865214_-	PspC domain-containing protein	NA	NA	NA	NA
WP_157599880.1\|3865239_3865422_-	hypothetical protein	NA	NA	NA	NA
WP_011497652.1\|3865418_3865736_-	hypothetical protein	NA	NA	NA	NA
WP_049763066.1\|3866060_3867089_-\|tRNA	tRNA dihydrouridine(20/20a) synthase DusA	NA	NA	NA	NA
WP_011497654.1\|3867208_3868279_+\|integrase	site-specific integrase	A0A1W6JP34	Morganella_phage	9.9e-113	55.9
WP_011497655.1\|3868296_3868869_+	SOS response-associated peptidase	NA	NA	NA	NA
WP_011497656.1\|3868869_3870126_-	Y-family DNA polymerase	I6RSM4	Salmonella_phage	1.4e-89	43.4
WP_011497657.1\|3870126_3870534_-	translesion error-prone DNA polymerase V autoproteolytic subunit	A0A1L5C2A3	Pseudoalteromonas_phage	6.1e-23	52.3
WP_011497658.1\|3870626_3870839_-	hypothetical protein	A0A2I7QRW3	Vibrio_phage	6.0e-14	58.6
WP_011497659.1\|3870864_3872646_-	hypothetical protein	A0A2I7QS09	Vibrio_phage	1.1e-140	44.9
WP_011497660.1\|3872649_3872949_-	hypothetical protein	NA	NA	NA	NA
WP_011497661.1\|3872941_3873946_-	hypothetical protein	A0A088C4T9	Shewanella_sp._phage	3.6e-32	33.6
WP_011497662.1\|3873970_3876376_-	hypothetical protein	A0A2I7QRV0	Vibrio_phage	5.9e-283	61.0
WP_041405870.1\|3876386_3876758_-	hypothetical protein	NA	NA	NA	NA
WP_011497664.1\|3876784_3881044_-\|tail	phage tail tape measure protein	A0A2I7QRW8	Vibrio_phage	3.9e-229	43.3
WP_011497665.1\|3881134_3881854_-	hypothetical protein	NA	NA	NA	NA
WP_011497666.1\|3881850_3882276_-	hypothetical protein	NA	NA	NA	NA
WP_011497667.1\|3882295_3882853_-	hypothetical protein	NA	NA	NA	NA
WP_011497668.1\|3882856_3883189_-	hypothetical protein	NA	NA	NA	NA
WP_011497669.1\|3883181_3883502_-	DUF2190 family protein	NA	NA	NA	NA
WP_083759699.1\|3883567_3885619_-\|protease	Clp protease ClpP	A0A1W6JT88	Pseudomonas_phage	7.5e-202	58.9
WP_011497671.1\|3885563_3887138_-\|portal	phage portal protein	K7PHM5	Enterobacterial_phage	5.1e-126	47.9
WP_011497672.1\|3887252_3887459_-	hypothetical protein	NA	NA	NA	NA
3887400:3887415	attR	NA	NA	NA	NA
WP_041405871.1\|3887487_3889470_-\|terminase	phage terminase large subunit family protein	A0A1B0Z2K0	Pseudomonas_phage	4.3e-194	50.5
WP_011497674.1\|3889444_3889975_-	DNA packaging protein	O64316	Escherichia_phage	4.1e-35	47.8
WP_157599881.1\|3889974_3890265_-	hypothetical protein	NA	NA	NA	NA
WP_011497676.1\|3890363_3890801_-	hypothetical protein	NA	NA	NA	NA
WP_011497677.1\|3890790_3891270_-	lysozyme	A0A1S5R1I9	Pseudomonas_phage	3.3e-36	49.4
WP_011497678.1\|3891266_3891614_-	DUF4406 domain-containing protein	A0A0U2SAZ1	Escherichia_phage	3.3e-25	54.6

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. NC_007954

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection