CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NC_008149	Yersinia pestis Nepal516, complete sequence	4 crisprs	cas3,DinG,DEDDh,cas6f,cas7f,cas5f,cas8f,cas3f,cas1	1	4	12	1
NC_008119	Yersinia pestis Nepal516 plasmid pPCP, complete sequence	0 crisprs	NA	0	0	0	0
NC_008118	Yersinia pestis Nepal516 plasmid pMT, complete sequence	0 crisprs	NA	0	0	2	0

Results visualization

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CRISPR-Cas detection and classification

Crispr_ID: NC_008149_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_008149_1

56389-56501

Orphan

Consensus_repeat	Method
CTTCACTCGGCTGCTCAAATGTGCTTT	CRISPRCasFinder

1 spacers

The CRISPR arrays of NC_008149_1

>merge|NC_008149|1|56389-56501|CRISPRCasFinder
CTTCACTCGGCTGCTCAAATGTGCTTTGGACGTCAACAACCCATTCAAAATCAAAAACGTATTAAAAGCCTAAGGATGATGGTCTGGCTTCACTCGCTGCTCAAATGTGCTTT

>NC_008149|1|1|56389-56501|CRISPRCasFinder
CTTCACTCGGCTGCTCAAATGTGCTTT	GGACGTCAACAACCCATTCAAAATCAAAAACGTATTAAAAGCCTAAGGATGATGGTCTG
GCTTCACTCGCTGCTCAAATGTGCTTT

Protein	Signature genes	Signature genes Name	Protein_function
NC_008149.1\|WP_002209484.1\|68143_68761_+\|heme-acquisition-protein-HasA	unknown	unknown	gnl\|CDD\|368907
NC_008149.1\|WP_002212099.1\|51780_53262_+\|type-VI-secretion-system-contractile-sheath-large-subunit	unknown	unknown	gnl\|CDD\|226048
NC_008149.1\|WP_002223919.1\|59930_61094_-\|acetylornithine-deacetylase	unknown	unknown	gnl\|CDD\|235346
NC_008149.1\|WP_002209481.1\|72203_73007_+\|energy-transducer-TonB	unknown	unknown	gnl\|CDD\|223880
NC_008149.1\|WP_002212097.1\|50173_50692_-\|Hcp-family-type-VI-secretion-system-effector	unknown	unknown	gnl\|CDD\|213799
NC_008149.1\|WP_002209487.1\|63457_64831_+\|argininosuccinate-lyase	unknown	unknown	gnl\|CDD\|179883
NC_008149.1\|WP_002221973.1\|45429_45666_+\|hypothetical-protein	unknown	unknown	unknown
NC_008149.1\|WP_002209482.1\|70810_72139_+\|HlyD-family-type-I-secretion-periplasmic-adaptor-subunit	unknown	unknown	gnl\|CDD\|130902
NC_008149.1\|WP_002209485.1\|65429_67922_+\|TonB-dependent-hemoglobin/transferrin/lactoferrin-family-receptor	unknown	unknown	gnl\|CDD\|273807
NC_008149.1\|WP_002209483.1\|68926_70735_+\|type-I-secretion-system-permease/ATPase	unknown	unknown	gnl\|CDD\|226969
NC_008149.1\|WP_002212092.1\|46849_48121_+\|maltoporin	unknown	unknown	gnl\|CDD\|236481
NC_008149.1\|WP_002209491.1\|56920_59557_-\|phosphoenolpyruvate-carboxylase	unknown	unknown	gnl\|CDD\|234570
NC_008149.1\|WP_002215335.1\|62514_63291_+\|acetylglutamate-kinase	unknown	unknown	gnl\|CDD\|239782
NC_008149.1\|WP_002212098.1\|51215_51713_+\|type-VI-secretion-system-contractile-sheath-small-subunit	unknown	unknown	gnl\|CDD\|226047
NC_008149.1\|WP_002209489.1\|61344_62349_+\|N-acetyl-gamma-glutamyl-phosphate-reductase	unknown	unknown	gnl\|CDD\|234761
NC_008149.1\|WP_002212100.1\|53268_53709_+\|type-VI-secretion-system-baseplate-subunit-TssE	unknown	unknown	gnl\|CDD\|226049
NC_008149.1\|WP_002212095.1\|49743_50022_+\|hypothetical-protein	unknown	unknown	unknown
NC_008149.1\|WP_100067904.1\|54824_56179_-\|IS3-like-element-IS1661-family-transposase	unknown	unknown	gnl\|CDD\|222853
NC_008149.1\|WP_002212093.1\|48361_49273_+\|maltose-operon-protein-MalM	unknown	unknown	gnl\|CDD\|236716
NC_008149.1\|WP_002212091.1\|45669_46779_+\|maltose/maltodextrin-ABC-transporter-ATP-binding-protein-MalK	unknown	unknown	gnl\|CDD\|182893

Protein	Function_ID	Function_description	E-value
NC_008149.1\|WP_002209484.1\|68143_68761_+\|heme-acquisition-protein-HasA	gnl\|CDD\|368907	pfam06438, HasA, Heme-binding protein A (HasA). Free iron is limited in vertebrate hosts, thus an alternative to siderophores has been developed by pathogenic bacteria to access host iron bound in protein complexes. HasA is a secreted hemophore that has the ability to obtain iron from hemoglobin. Once bound to HasA, the heme is shuttled to the receptor HasR, which releases the heme into the bacterium.	9.51098e-102
NC_008149.1\|WP_002212099.1\|51780_53262_+\|type-VI-secretion-system-contractile-sheath-large-subunit	gnl\|CDD\|226048	COG3517, COG3517, Predicted component of the type VI protein secretion system [Intracellular trafficking, secretion, and vesicular transport].	0
NC_008149.1\|WP_002223919.1\|59930_61094_-\|acetylornithine-deacetylase	gnl\|CDD\|235346	PRK05111, PRK05111, acetylornithine deacetylase; Provisional.	0
NC_008149.1\|WP_002209481.1\|72203_73007_+\|energy-transducer-TonB	gnl\|CDD\|223880	COG0810, TonB, Periplasmic protein TonB, links inner and outer membranes [Cell envelope biogenesis, outer membrane].	1.51188e-39
NC_008149.1\|WP_002212097.1\|50173_50692_-\|Hcp-family-type-VI-secretion-system-effector	gnl\|CDD\|213799	TIGR03344, VI_effect_Hcp1, type VI secretion system effector, Hcp1 family. This family includes Hcp1 (hemolysin coregulated protein 1), an exported, homohexameric ring-forming virulence protein from Pseudomonas aeruginosa. Hcp1 lacks a conventional signal sequence and is instead exported by means of the type VI secretion system, encoded by a pathogenicity cluster of a class previously designated IAHP (IcmF-associated homologous protein). Homologs of Hcp1, in this protein family, are found in various bacteria of which most but not all are known pathogens. Pathogens may have many multiple members of this family, with three to ten in Erwinia carotovora, Yersinia pestis, uropathogenic Escherichia coli, and the insect pathogen Photorhabdus luminescens. [Cellular processes, Pathogenesis].	1.15477e-84
NC_008149.1\|WP_002209487.1\|63457_64831_+\|argininosuccinate-lyase	gnl\|CDD\|179883	PRK04833, PRK04833, argininosuccinate lyase; Provisional.	0
NC_008149.1\|WP_002209485.1\|65429_67922_+\|TonB-dependent-hemoglobin/transferrin/lactoferrin-family-receptor	gnl\|CDD\|273807	TIGR01785, Heme/hemopexin_utilization_protein_C, TonB-dependent heme/hemoglobin receptor family protein. This model represents the TonB-dependent outer membrane heme/hemoglobin receptor/transporter found in bacteria which live in contact with animals (which contain hemoglobin or other heme-bearing globins) or legumes (which contain leghemoglobin). Some species having hits to this model such as Nostoc, Caulobacter and Chlorobium do not have an obvious source of hemoglobin-like proteins in their biological niche and so the possibility exists that they act on some other substance. [Transport and binding proteins, Cations and iron carrying compounds, Transport and binding proteins, Porins].	8.20794e-132
NC_008149.1\|WP_002209483.1\|68926_70735_+\|type-I-secretion-system-permease/ATPase	gnl\|CDD\|226969	COG4618, ArpD, ABC-type protease/lipase transport system, ATPase and permease components [General function prediction only].	0
NC_008149.1\|WP_002212092.1\|46849_48121_+\|maltoporin	gnl\|CDD\|236481	PRK09360, lamB, maltoporin LamB.	0
NC_008149.1\|WP_002209491.1\|56920_59557_-\|phosphoenolpyruvate-carboxylase	gnl\|CDD\|234570	PRK00009, PRK00009, phosphoenolpyruvate carboxylase; Reviewed.	0
NC_008149.1\|WP_002215335.1\|62514_63291_+\|acetylglutamate-kinase	gnl\|CDD\|239782	cd04249, AAK_NAGK-NC, AAK_NAGK-NC: N-Acetyl-L-glutamate kinase - noncyclic (NAGK-NC) catalyzes the phosphorylation of the gamma-COOH group of N-acetyl-L-glutamate (NAG) by ATP in the second step of microbial arginine biosynthesis using the acetylated, noncyclic route of ornithine biosynthesis. There are two variants of this pathway. In one, typified by the pathway in Escherichia coli, glutamate is acetylated by acetyl-CoA and acetylornithine is deacylated hydrolytically. In this pathway, feedback inhibition by arginine occurs at the initial acetylation of glutamate and not at the phosphorylation of NAG by NAGK. Homodimeric NAGK-NC are members of the Amino Acid Kinase Superfamily (AAK).	2.52737e-136
NC_008149.1\|WP_002212098.1\|51215_51713_+\|type-VI-secretion-system-contractile-sheath-small-subunit	gnl\|CDD\|226047	COG3516, COG3516, Predicted component of the type VI protein secretion system [Intracellular trafficking, secretion, and vesicular transport].	6.35023e-71
NC_008149.1\|WP_002209489.1\|61344_62349_+\|N-acetyl-gamma-glutamyl-phosphate-reductase	gnl\|CDD\|234761	PRK00436, argC, N-acetyl-gamma-glutamyl-phosphate reductase; Validated.	0
NC_008149.1\|WP_002212100.1\|53268_53709_+\|type-VI-secretion-system-baseplate-subunit-TssE	gnl\|CDD\|226049	COG3518, COG3518, Predicted component of the type VI protein secretion system [Intracellular trafficking, secretion, and vesicular transport].	6.737e-48
NC_008149.1\|WP_002209482.1\|70810_72139_+\|HlyD-family-type-I-secretion-periplasmic-adaptor-subunit	gnl\|CDD\|130902	TIGR01843, Hemolysin_secretion_protein_D_plasmid, type I secretion membrane fusion protein, HlyD family. Type I secretion is an ABC transport process that exports proteins, without cleavage of any signal sequence, from the cytosol to extracellular medium across both inner and outer membranes. The secretion signal is found in the C-terminus of the transported protein. This model represents the adaptor protein between the ATP-binding cassette (ABC) protein of the inner membrane and the outer membrane protein, and is called the membrane fusion protein. This model selects a subfamily closely related to HlyD; it is defined narrowly and excludes, for example, colicin V secretion protein CvaA and multidrug efflux proteins. [Protein fate, Protein and peptide secretion and trafficking].	3.16318e-105
NC_008149.1\|WP_100067904.1\|54824_56179_-\|IS3-like-element-IS1661-family-transposase	gnl\|CDD\|222853	PHA02517, PHA02517, putative transposase OrfB; Reviewed.	9.01643e-48
NC_008149.1\|WP_002212093.1\|48361_49273_+\|maltose-operon-protein-MalM	gnl\|CDD\|236716	PRK10564, PRK10564, maltose operon protein MalM.	5.256e-172
NC_008149.1\|WP_002212091.1\|45669_46779_+\|maltose/maltodextrin-ABC-transporter-ATP-binding-protein-MalK	gnl\|CDD\|182893	PRK11000, PRK11000, maltose/maltodextrin ABC transporter ATP-binding protein MalK.	0

>NC_008149.1|WP_100067904.1|54824_56179_-|IS3-like-element-IS1661-family-transposase
MKHPFSTRLAAVQHYLSGKATLRETARQFSVGKSPLTRWIRAFRRQGEAGLEHHLSRTYTPEFRLCVVRYMMANRCSAADASAHFNIPNETIIQNWMKRYREGGKEALNPSKTGPTMPKDKYEHDSKPFSEMTHAELEKELEYLRAENAYPKKAESPERRKGTQGAAEKTRIVQALTAEHRLSCLLCAAKLARSTYYYHASKPDGVIDDYADAVKAIGALSRRHAQRYGYRRMTVALRKEGFTLNHKTVRKLMNQHGLLSLIRRKKYRSYRADGGRASDNLLARNFTSEISGLKWCTDVTEFRVGAQKLYLSVIQDLFNNEIISWHMSERAALILTCKTLEKALKVKGRKEGLMLHSDQGWHYRTPMWRSMLVEAGIRQSMSRKGNCLDNAVMENFFSHLKAEMYHRKKYDSATVLKRDIVEYIHYYNTERISLKTGGMSPAEYRTQVEKQ
>NC_008149.1|WP_002212100.1|53268_53709_+|type-VI-secretion-system-baseplate-subunit-TssE
MAALLNWDRGSSASLFDRIQGKGASSSSDGRLRELLNSIQKHLNEVLNSRPGACQSAVDLGVIDLNDATATSSDFRKSIEKAIKDCIENYEPRISAVTVQSLLNHGDPLQLSFHISARVNFDDMGDVVEFNIQLDNNRRYCFNQET
>NC_008149.1|WP_002212099.1|51780_53262_+|type-VI-secretion-system-contractile-sheath-large-subunit
MPLHEENTVLAAEPASATFLLDEIMSQTRMAPGNDGYDIAKQGVAAFISSILDTGTNEEPINKLLVDRMIIELDKKLSAQMDEILHANEFREIESSWRSLKLLVDRTDFRENIKINIMHATKEELLEDFEFSPEIIQSGFYKHVYSSGYGQFGGEPTAAIIGNYAFNNSSPDMKLLQYVSAVGAMAHAPFLSSVAPDFFGISSFTELPAIKDLKSVFEGPAHTKWRALRESEDSRYLGLTTPRFLLRLPYSTVENPIKNFNYYEDVSRNHEHFLWGNTAFLLASCLTDSFAKYRWCPNIIGPQSGGTVHDLPVHLYEAMGQIQAKIPTEVLITDRREFELAEEGFITLTMRKGSDNAAFFSANSVQKPKVFPNTREGKMAETNYKLGTQLPYMFVINRLAHYIKVLQREQIGSWKERQDLERELNIWLKQYIADQENPPTDVRSRRPLRSAQIQVLDVEGDPGWYQVAMQVRPHFKYMGASFELSLVGRLDKE
>NC_008149.1|WP_002212098.1|51215_51713_+|type-VI-secretion-system-contractile-sheath-small-subunit
MSKNKQSSVAPKERINIKYVPNTGDQVAEIELPLNLLVVGDLKGVREETSIEERQVVSVNKNNFNSVMNEANISLSFNVPNRLEGDGEEDMPVALSIKGLDDFSPDNVAKKVPELKKILELREALVALKGPLGNIPAFRSRLQDLLGNEDMREQLLKELDILNQK
>NC_008149.1|WP_002212097.1|50173_50692_-|Hcp-family-type-VI-secretion-system-effector
MPTPAYISITGKTQGNITAGAFTAESVGNIYVQGHEDEMLVQEFEHIVTVPTDPQSGQPSGQRAHKPLRFTVAYNKAVPLLYNALASGEMLPTVELKWYRTSIEGKQEHFFTTKLEDATIIDIDCKMPHCQDSTKAEFTQLVRVSLAYRKINWDHTTAGTSGADDWRAPIEA
>NC_008149.1|WP_002212095.1|49743_50022_+|hypothetical-protein
MNFPNLLLLFSDGTLIKQVERELKTHLICNEFVKNKSKIVTVYITLGNDALLLIYYSNRVFYKKSYIKCGDIACMNYTVNEGYLTTEIILWR
>NC_008149.1|WP_002212093.1|48361_49273_+|maltose-operon-protein-MalM
MKKNLLSLCLVLALGGTAPLAVQAASTISPANVSIAPTISTTTLQQLPWQPLVPPVTQDIQLTAGSPHISQGEVEGAVAAFALPADRGSLEVTLSSLLTDKQLFTPSVLVLDEQMRPAAYYPSSYFTYEKAGIMINDRLQGVMKLTPALGQKQIYLLVYTTRDDLKKTTQLLDPAKAYAQGVGNAVPDIPDPIVNHSPTGTLRIKVTSEQGMGNIMIGLIQSAPTSAPVVVGSSIQPVAAPQSEPAKPAAPMLGETENYFNQAIKDAVKAGDVDKALKLLNEAEHLGSTSARKTFIGSVKGKG
>NC_008149.1|WP_002212092.1|46849_48121_+|maltoporin
MITLRKLPIALAVAAGVLSTQAMAVDFHGYARSGIGWTASGGEQQCFQTTGAQSKYRLGNECETYAELKLGQELWKEGDKSFYLDTNVAYSVSQRDDWESTDPAFREANVQGKNLIESLPGSTIWAGKRFYQRHDVHMIDFYYWDISGPGAGLETIDLGFGKLSVAATRNSESGGSSAWIDNQRENAKYTINNVYDVRLAGLETNPGGSLELGVDYGRADTQEGYSLAPNASKDGVMLTAEHTQSLMGGFNKFVVQYATDSMTSYNTGHSQGTSVNNNGHLLRVIDHGAINLAEKWDMMYVALYQDIDLDNNNGNTWYSVGVRPMYKWTPIMSTLLEAGYDNVKSQHTGERNGQYKLTLAQQWQAGDSIWSRPAIRVFATYANWDEKWGYSDTTGVAQDGTIGTNSRGKNNEVTFGAQFEAWW
>NC_008149.1|WP_002212091.1|45669_46779_+|maltose/maltodextrin-ABC-transporter-ATP-binding-protein-MalK
MANVTLSSVYKAFGEAVISRDINLEIDDGEFVVFVGPSGCGKSTLLRMIAGLEDITSGELLIGGKRMNEVPPSERGIGMVFQSYALYPHLSVAENMSFGLKLAGVKKAEIYQRVNQVAEVLQLAHLLDRRPKALSGGQRQRVAIGRTLVSEPDVFLLDEPLSNLDAALRVQMRIEISRLHKRLERTMIYVTHDQVEAMTLADKIVVLDAGNIAQVGKPLELYHYPANRFVAGFIGSPKMNFLPVKVTAAEPRQVQIELPNHQRVWLPVEGDQVQVGANMSLGIRPEHLLPSSASEVTLEGEIQVVEQLGNETQIHIQIPAIRQNLVYRQNDVVLVEEGATFSIGLPPHRCHLFREDGTACKRLYQELGV
>NC_008149.1|WP_002221973.1|45429_45666_+|hypothetical-protein
MRLIITLLDQYVEALFNVQPYTQAATPSGATLPLAWRHGAQRESHQGTGGNQWVMPGFASTVFLHSDSYEKLFAQAKE
>NC_008149.1|WP_002209491.1|56920_59557_-|phosphoenolpyruvate-carboxylase
MNEQYSAMRSNVSMLGTLLGDTIKEALGEHILDRVETIRKLSKSSRAGNEASRQELLTTLQNLSNDELLPVARAFSQFLNLTNTAEQYHSISPHGEAASNPEALAQLFTRLKDKKLSDQDMRSAVDDLSIELVLTAHPTEITRRTLIHKLVEVNTCLSQLDHNDLADYERNKIMRRLRQLVAQSWHTDEIRKLRPSPVDEAKWGFAVVENSLWEGVPAFLREFNEQLENSLDYRLPVEAVPIRFTSWMGGDRDGNPNVTAEITRHVLLLSRWKATDLFLRDIQVLVSELSMSECTPELRELAGGEEVLEPYRQLMKNVRTQLTNTQAYLEARLKGERVLPPHDLLVSNDQLWEPLYACYQSLKACGMEIIANGQLLDTLRRVRCFGVPLVRIDVRQESTRHTDAIAELTRYLGLGDYESWSESDKQAFLVRELNSKRPLVPLKWEPSAETQEVLETCRVIAEAPQGSIAAYVISMAKVPSDVLAVHLLLKEAGCPFTLPVAPLFETLDDLNNADDVMTQLLGIDWYRGLIQGKQMVMIGYSDSAKDAGVMAASWAQYRAQDALIKTCEKAGITLTLFHGRGGSIGRGGAPAHAALLSQPPGSLKGGLRVTEQGEMIRFKFGLPEVTISSLALYAGAILEANLLPPPEPKKEWIEVMDLLSDASCDMYRSYVRENPEFVRYFRAATPELELGKLPLGSRPAKRRPDGGVESLRAIPWIFAWTQNRLMLPAWLGAGAGLQRAIDAGKQDVLATMCRDWPFFSTRIGMLEMVFAKADLWLAEYYDQRLVDKSLWPLGQQLRDQLAADIKVVLAIANDDHLMADLPWIAESIALRNVYTDPLNVLQAELLHRSRQQEHPDACVEQALMVTIAGVAAGMRNTG
>NC_008149.1|WP_002223919.1|59930_61094_-|acetylornithine-deacetylase
MKLPPFIELYRALIATPSISAADSALDQSNEALINLLAGWFADLGFRVEIQPVPDTRHKFNLLASIGENENGEGHGGLLLAGHTDTVPYDEGRWTRDPFTLTEHDHKLYGLGTADMKGFFAFILDAVRDIDASKLTKPLYILATADEETTMAGARYFAANTQLRPDFAIIGEPTSLQPVRAHKGHISNAIRITGQSGHSSDPARGVNAIDLMHESITQLMALRTTLQERYHNPAFTIPYPTMNFGHINGGDAANRICACCELHMDIRPLPGLTLSDLNELMTEALEPVSQRWPGRLSIDELHPPIPGYECPTDHHMVGVIEKLLGERTAVVNYCTEAPFIQQVCPTLVLGPGSINQAHQPDEFIDMAFIEPTRELIGQLVDHFCQQK
>NC_008149.1|WP_002209489.1|61344_62349_+|N-acetyl-gamma-glutamyl-phosphate-reductase
MLNTLIVGASGYAGAELTAYLNRHPHMNITGLAVSAQSADAGKLLSDLHPQLKGILDLPLQPLVDVAQAAKGIDVVFLATAHEVSHDLAPQFLAAGCVVFDLSGAFRVRDAAFYSQYYGFEHQHPDWLDKAVYGLAEWQSEDIKQAQLIAVPGCYPTASQLALKPLVDGQLLNDAQWPVINAVSGVSGAGRKASMGNSFCEVSLQPYGLFTHRHQPEIVTHLGTPVIFTPHLGNFARGILATITCRLKAGVTAQNIADAYHHAYQNKPLVRLYQQGVPALKAVVGLPFCDIGFSVQGEHLIIVATEDNLLKGAAAQAVQCMNIRFGFPETQSLL
>NC_008149.1|WP_002215335.1|62514_63291_+|acetylglutamate-kinase
MMNPLVIKLGGVLLDSEEALERLFTALVTYREKHERPLVIMHGGGCLVDELMKRLALPVVKKNGLRVTPADQIDIITGALAGTANKTLLAWAVKHQINAVGLCLADGNTVTVTLLDAELGHVGKAQPGSAALVQTLLAAGYMPIISSIGITVEGQLMNVNADQAATALAATLGADLILLSDVSGILDGKGQRIAEMTAQKAEQLIAQGIITDGMVVKVNAALDAARSLGRPVDIASWRHSEQLPALFNGVPIGTRISV
>NC_008149.1|WP_002209487.1|63457_64831_+|argininosuccinate-lyase
MALWGGRFSQAADQRFKQFNDSLRFDYRLAEQDIIGSVAWSKALVTVGVLNADEQQQLEQALSVLLEEVQANPHAILASDAEDIHSWVETKLIDKVGDLGKKLHTGRSRNDQVATDLKLWCKFQITELQTAVQQLQQALVMTAEANQDAVMPGYTHLQRAQPVTFAHWCLAYVEMLSRDESRLQDTLKRLDVSPLGCGALAGTAYAIDREQLAGWLGFASATRNSLDSVSDRDHVLELLSDASIGMVHLSRFAEDLIFFNSGEAAFVDLSDRVTSGSSLMPQKKNPDALELIRGKCGRVQGALTGMTMTLKGLPLAYNKDMQEDKEGLFDALDTWLDCLHMAALVLDGIQVKRPRCKEAAEQGYANATELADYLVAKGVPFREAHHIVGEAVVEAIRQGKALEALALSDLQQFSSVIGDDVYPILALQSCLDKRVAKGGVSPQQVASAIAEAKARLF
>NC_008149.1|WP_002209485.1|65429_67922_+|TonB-dependent-hemoglobin/transferrin/lactoferrin-family-receptor
MDNIIRDKKTIISVNKITTCILFALVTQGYSGQLAANTAETPTNNNDMALDKLNVEGKGNAHDSDWIYDEPRSVSEITREQLDNRPARHAADILEQTPGVYSSVSQQDPGLSINIRGIQDYGRVNMNIDGMRQNFMKSGHGQRNGSMYIDPEILSNVVIERGIFNGIGGAGAIGGIATFNTINASDFLAPEKELGGHIRAMTGDNGTRFIGSGALALGNPNGDILLAVSERNLKDYWPGNKGVLAGLRLYSPTRNVGDDLKNTKTLFTGYKMRSQLAKVGWNFEAGQRLEFSYLQTQIASPNASMLSEVLALSPSGKEITKIGWRNTSFTNVENRNIALDYRLNPEHISWLDATAKIYYVDTNDETDNANSLFKEYFWTQTRLKTRGLQLQNTNTFTPSDAHQIRLKYGLEWFSDKSEGYSTRKLIERTTPPGKRAITSTFAQLNYEYDDWLRLEGGLRYDQFRLKGNTWLHTRSFLQPYTFENPCDRRIHEQSEKPGSRCSSRRPATMRWDVDRCEQQLSPTLAMGVKPGLEWLEFFGSYGKSWRPPAMTEVLATGTAHGYSWVLPNPFVAAERARTWEAGFNIQQSNLFIEDDHFAAKVAYFDTRIANYINLELGKAKPKFGGDSFTDVAYVNNLLKTRFRGLEYQLSYDAGTFYTNINYTRMIGVNNVCSPYAWLGGLQSVKYKYVGKVEQIYAVENEVANNYVTCMNANVLFGSSAYLPGDRGSLTLGSRIFDRRLDFGTVIRYNKGYQDRSAQDENGNPLTAYVADWPKYIVYDLYASYKVTNNLILRSSIENITNRAYLVNYGDTLSFAPSRGRTIQGGFEYKF
>NC_008149.1|WP_002209484.1|68143_68761_+|heme-acquisition-protein-HasA
MSTTIQYNSNYADYSISSYLREWANNFGDIDQAPAETKDRGSFSGSSTLFSGTQYAIGSSHSNPEGMIAEGDLKYSFMPQHTFHGQIDTLQFGKDLATNAGGPSAGKHLEKIDITFNELDLSGEFDSGKSMTENHQGDMHKSVRGLMKGNPDPMLEVMKAKGINVDTAFKDLSIASQYPDSGYMSDAPMVDTVGVVDCHDMLLAA
>NC_008149.1|WP_002209483.1|68926_70735_+|type-I-secretion-system-permease/ATPase
MESCKTPGASSVPPTILSVLAGNKKILWGIGLFTAVINLLMLAPAIYMLQVYDRVLASANTMTLLMLTVLVLGVFVFIGLLEWVRSAVVIRLGTQIDMQLNQPVFNAAFAANLKGHNTPAAQALNDLTVLRQFATGNALFAFFDAPWFPLYLLVIFLLHPWLGMLAAAGAGILVVLAWLNQWICKKPLHDASIITSHATQQANANLRNADVIEAMGMLKALRERWLMQHANFLYQQNLASDKSSRVTAVAKSSRQALQSMMLGLGALLVIYNEITAGVMIAGSILIGRVLGPIDQLIAVWKQWSHARLAYQRLSQLLAQHPSSPTGMVLPAPQGKLNVTQLMACKPGTHIPVLHSINFELQPGDVLGILGPSGSGKSTLAKLLVASQPTFSGTVRLDSADLSRWDKTQLGEFIGYLPQNIQLFRGTVAENIARFGAIDTAKVVAAAQLADVHDLILHLPQGYDTPLGDDGEGLSGGQRQRIALARAMYGIPRLIVLDEPNASLDKEGEQALLASIIQLKQQGCTIVMITHKPELLSGSDYLLFLKNGQMDLFDRTQAVLQNIQGKDKPAVQPEAKILNSRSGWSNGVSYGIGPARTTSSPKP
>NC_008149.1|WP_002209482.1|70810_72139_+|HlyD-family-type-I-secretion-periplasmic-adaptor-subunit
MLPESVCYSVANANRQPPLQINSGRYLNIGGGLVVIGFIGFLLWAGLAPLDKGVAVTGLLVVAENRKVIQPLQGGRIQQLHVTEGDEIVSGQLLVTLDDTAIRNQRDNLQHQYLSALAQEARLTAEQNDLDVITFPQALLEHATQPAVERNIILQQQLLHHRRQAHLSEIARLSTQLTRHQARLDGLQAMRSNHQRQSNLFQQQLDSVQLLAKDGHIAKNKLLEMESQSTSLQARVEQSTSDIAEAHKLIDETEQHVLQRREQYQSENSEQLAKAQQNTQELVQRLNIAEYELSHTRIFAPVSGSVIALAQHTVGGVVSSGQALMEIVPSGQPLFVEAQLPVELIDKVAVGLPVDLNFSAFNQSNTPRLQGSVWRIGADRIQPPPTSPPYYPLTVAIDLDPTELAIRPGMAVDVFIRTGERSLLSYLFKPFTDRLHLALAEE
>NC_008149.1|WP_002209481.1|72203_73007_+|energy-transducer-TonB
MNRLQQSSDKLIFWLVGALLACGIHIYALWWLSTASIPAIPTSYPAAIMMELSAEPEFMQNLPQNSVVGITQNIIEPAVEQRVNQPDDIVDLPTLPEQPEGQREITRKEPIKVKRPAENRATSRKPVNKETQESDSKQSSPAAAASAMLSGTSQQVAAAVNSDSSHRQQAQVSWKSRLQGHLMGFKRYPSSARKQQQQGTAMIRFVVDKNGYVSSVQLSHSSGTSALDREALAIIKRAQPLPKPPAELLSQGQITLSLPVDFNLKRK

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Crispr_ID: NC_008149_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_008149_2

1221364-1221633

Orphan

I-F

Consensus_repeat	Method
GTTCACTGCCGCACAGGCAGCTTAGAAA	PILER-CR
GTTCACTGCCGCACAGGCAGCTTAGAAA	CRISPRCasFinder
GTTCACTGCCGCACAGGCAGCTTAGAAA	CRT

4 spacers

The CRISPR arrays of NC_008149_2

>merge|NC_008149|2|1221364-1221633|PILER-CR,CRISPRCasFinder,CRT
GTTCACTGCCGCACAGGCAGCTTAGAAACTGATACAATCATCCTATTTGTCCTATCCAGAAGTTCACTGCCGCACAGGCAGCTTAGAAAGACAAGAACCGAATCTTTCGCCGTGCCGTAAAGTTCACTGCCGCACAGGCAGCTTAGAAACCGAAATCATCAGATGTAATTAAGATTTTTGCTGTTCACTGCCGCACAGGCAGCTTAGAAAAGACTGATGCAAGATGGCGGTATGCGTACAGAGTTCACTGCCGCACAGGCAGCTTATAGA

>NC_008149|2|1|1221364-1221573|PILER-CR
GTTCACTGCCGCACAGGCAGCTTAGAAA	CTGATACAATCATCCTATTTGTCCTATCCAGAA
GTTCACTGCCGCACAGGCAGCTTAGAAA	GACAAGAACCGAATCTTTCGCCGTGCCGTAAA
GTTCACTGCCGCACAGGCAGCTTAGAAA	CCGAAATCATCAGATGTAATTAAGATTTTTGCT
GTTCACTGCCGCACAGGCAGCTTAGAAA

>NC_008149|2|2|1221364-1221633|CRISPRCasFinder
GTTCACTGCCGCACAGGCAGCTTAGAAA	CTGATACAATCATCCTATTTGTCCTATCCAGAA
GTTCACTGCCGCACAGGCAGCTTAGAAA	GACAAGAACCGAATCTTTCGCCGTGCCGTAAA
GTTCACTGCCGCACAGGCAGCTTAGAAA	CCGAAATCATCAGATGTAATTAAGATTTTTGCT
GTTCACTGCCGCACAGGCAGCTTAGAAA	AGACTGATGCAAGATGGCGGTATGCGTACAGA
GTTCACTGCCGCACAGGCAGCTTATAGA

>NC_008149|2|1|1221364-1221633|CRT
GTTCACTGCCGCACAGGCAGCTTAGAAA	CTGATACAATCATCCTATTTGTCCTATCCAGAA
GTTCACTGCCGCACAGGCAGCTTAGAAA	GACAAGAACCGAATCTTTCGCCGTGCCGTAAA
GTTCACTGCCGCACAGGCAGCTTAGAAA	CCGAAATCATCAGATGTAATTAAGATTTTTGCT
GTTCACTGCCGCACAGGCAGCTTAGAAA	AGACTGATGCAAGATGGCGGTATGCGTACAGA
GTTCACTGCCGCACAGGCAGCTTATAGA

Protein	Signature genes	Signature genes Name	Protein_function
NC_008149.1\|WP_002227852.1\|1207064_1207316_+\|hypothetical-protein	unknown	unknown	unknown
NC_008149.1\|WP_002223323.1\|1228697_1230245_+\|sugar-ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|224053
NC_008149.1\|WP_002210302.1\|1230256_1231285_+\|ABC-transporter-permease	unknown	unknown	gnl\|CDD\|224093
NC_008149.1\|WP_002209748.1\|1207923_1208325_-\|DUF1240-domain-containing-protein	unknown	unknown	gnl\|CDD\|336520
NC_008149.1\|WP_138921619.1\|1210938_1213251_-\|penicillin-binding-protein-1C	unknown	unknown	gnl\|CDD\|273954
NC_008149.1\|WP_002210296.1\|1221636_1222491_-\|MurR/RpiR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|224651
NC_008149.1\|WP_002210300.1\|1227719_1228649_+\|substrate-binding-domain-containing-protein	unknown	unknown	gnl\|CDD\|380623
NC_008149.1\|WP_002223316.1\|1220454_1221003_-\|DUF1440-domain-containing-protein	unknown	unknown	gnl\|CDD\|226008
NC_008149.1\|WP_002210303.1\|1231308_1232442_+\|Gfo/Idh/MocA-family-oxidoreductase	unknown	unknown	gnl\|CDD\|223745
NC_008149.1\|WP_002214721.1\|1234458_1235517_+\|myo-inosose-2-dehydratase	unknown	unknown	gnl\|CDD\|275172
NC_008149.1\|WP_002359655.1\|1224389_1226315_+\|3D-(3,5/4)-trihydroxycyclohexane-1,2-dione-acylhydrolase-(decyclizing)	unknown	unknown	gnl\|CDD\|226471
NC_008149.1\|WP_002209751.1\|1206786_1207026_+\|hypothetical-protein	unknown	unknown	unknown
NC_008149.1\|WP_002209749.1\|1207339_1207912_+\|Hcp-family-type-VI-secretion-system-effector	unknown	unknown	gnl\|CDD\|213799
NC_008149.1\|WP_002210297.1\|1222828_1224355_+\|CoA-acylating-methylmalonate-semialdehyde-dehydrogenase	unknown	unknown	gnl\|CDD\|143404
NC_008149.1\|WP_002209746.1\|1208557_1208959_-\|DUF1240-domain-containing-protein	unknown	unknown	gnl\|CDD\|336520
NC_008149.1\|WP_002210306.1\|1235526_1236342_+\|5-deoxy-glucuronate-isomerase	unknown	unknown	gnl\|CDD\|226241
NC_008149.1\|WP_002210304.1\|1232473_1234444_+\|5-dehydro-2-deoxygluconokinase	unknown	unknown	gnl\|CDD\|378281
NC_008149.1\|WP_002209745.1\|1210480_1210726_+\|helix-turn-helix-domain-containing-protein	unknown	unknown	gnl\|CDD\|372675
NC_008149.1\|WP_002213775.1\|1213496_1213955_+\|IS200/IS605-like-element-IS1541B-family-transposase	unknown	unknown	gnl\|CDD\|224854
NC_008149.1\|WP_002210294.1\|1214069_1220048_-\|alpha-2-macroglobulin-family-protein	unknown	unknown	gnl\|CDD\|225248

Protein	Function_ID	Function_description	E-value
NC_008149.1\|WP_002359655.1\|1224389_1226315_+\|3D-(3,5/4)-trihydroxycyclohexane-1,2-dione-acylhydrolase-(decyclizing)	gnl\|CDD\|226471	COG3962, COG3962, Acetolactate synthase [Amino acid transport and metabolism].	0
NC_008149.1\|WP_002223323.1\|1228697_1230245_+\|sugar-ABC-transporter-ATP-binding-protein	gnl\|CDD\|224053	COG1129, MglA, ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism].	0
NC_008149.1\|WP_002210302.1\|1230256_1231285_+\|ABC-transporter-permease	gnl\|CDD\|224093	COG1172, AraH, Ribose/xylose/arabinose/galactoside ABC-type transport systems, permease components [Carbohydrate transport and metabolism].	8.15893e-97
NC_008149.1\|WP_002209748.1\|1207923_1208325_-\|DUF1240-domain-containing-protein	gnl\|CDD\|336520	pfam06836, DUF1240, Protein of unknown function (DUF1240). This family consists of a number of hypothetical putative membrane proteins which seem to be specific to Yersinia pestis. The function of this family is unknown.	7.32611e-43
NC_008149.1\|WP_138921619.1\|1210938_1213251_-\|penicillin-binding-protein-1C	gnl\|CDD\|273954	TIGR02073, Includes:_Penicillin-insensitive_transglycosylase, penicillin-binding protein 1C. This subfamily of the penicillin binding proteins includes the member from E. coli designated penicillin-binding protein 1C. Members have both transglycosylase and transpeptidase domains and are involved in forming cross-links in the late stages of peptidoglycan biosynthesis. All members of this subfamily are presumed to have the same basic function. [Cell envelope, Biosynthesis and degradation of murein sacculus and peptidoglycan].	0
NC_008149.1\|WP_002210296.1\|1221636_1222491_-\|MurR/RpiR-family-transcriptional-regulator	gnl\|CDD\|224651	COG1737, RpiR, Transcriptional regulators [Transcription].	1.17523e-68
NC_008149.1\|WP_002210300.1\|1227719_1228649_+\|substrate-binding-domain-containing-protein	gnl\|CDD\|380623	cd19968, PBP1_ABC_IbpA-like, periplasmic sugar-binding protein IbpA of an ABC transporter and similar proteins. The periplasmic binding protein (PBP) IbpA mediates the uptake of myo-inositol by an ABC transporter that consists of the PBP IbpA, the transmembrane permease IatP, and the ABC IatA. IbpA shares homology with a family of pentose/hexose sugar-binding proteins of the type 1 periplasmic binding protein superfamily, which consists of two domains connected by a three-stranded hinge.	4.31227e-120
NC_008149.1\|WP_002223316.1\|1220454_1221003_-\|DUF1440-domain-containing-protein	gnl\|CDD\|226008	COG3477, COG3477, Predicted periplasmic/secreted protein [Function unknown].	1.03166e-68
NC_008149.1\|WP_002210303.1\|1231308_1232442_+\|Gfo/Idh/MocA-family-oxidoreductase	gnl\|CDD\|223745	COG0673, MviM, Predicted dehydrogenases and related proteins [General function prediction only].	2.07432e-69
NC_008149.1\|WP_002214721.1\|1234458_1235517_+\|myo-inosose-2-dehydratase	gnl\|CDD\|275172	TIGR04379, myo-inositol_catabolism_protein, myo-inosose-2 dehydratase. Members of this family include the enzyme myo-inosose-2 dehydratase, product of the gene iolE, as found in inositol utilization cassettes in many species. [Energy metabolism, Sugars].	4.28689e-165
NC_008149.1\|WP_002209749.1\|1207339_1207912_+\|Hcp-family-type-VI-secretion-system-effector	gnl\|CDD\|213799	TIGR03344, VI_effect_Hcp1, type VI secretion system effector, Hcp1 family. This family includes Hcp1 (hemolysin coregulated protein 1), an exported, homohexameric ring-forming virulence protein from Pseudomonas aeruginosa. Hcp1 lacks a conventional signal sequence and is instead exported by means of the type VI secretion system, encoded by a pathogenicity cluster of a class previously designated IAHP (IcmF-associated homologous protein). Homologs of Hcp1, in this protein family, are found in various bacteria of which most but not all are known pathogens. Pathogens may have many multiple members of this family, with three to ten in Erwinia carotovora, Yersinia pestis, uropathogenic Escherichia coli, and the insect pathogen Photorhabdus luminescens. [Cellular processes, Pathogenesis].	2.31704e-76
NC_008149.1\|WP_002210297.1\|1222828_1224355_+\|CoA-acylating-methylmalonate-semialdehyde-dehydrogenase	gnl\|CDD\|143404	cd07085, ALDH_F6_MMSDH, Methylmalonate semialdehyde dehydrogenase and ALDH family members 6A1 and 6B2. Methylmalonate semialdehyde dehydrogenase (MMSDH, EC=1.2.1.27) [acylating] from Bacillus subtilis is involved in valine metabolism and catalyses the NAD+- and CoA-dependent oxidation of methylmalonate semialdehyde into propionyl-CoA. Mitochondrial human MMSDH ALDH6A1 and Arabidopsis MMSDH ALDH6B2 are also present in this CD.	0
NC_008149.1\|WP_002209746.1\|1208557_1208959_-\|DUF1240-domain-containing-protein	gnl\|CDD\|336520	pfam06836, DUF1240, Protein of unknown function (DUF1240). This family consists of a number of hypothetical putative membrane proteins which seem to be specific to Yersinia pestis. The function of this family is unknown.	5.05571e-40
NC_008149.1\|WP_002210306.1\|1235526_1236342_+\|5-deoxy-glucuronate-isomerase	gnl\|CDD\|226241	COG3718, IolB, Uncharacterized enzyme involved in inositol metabolism [Carbohydrate transport and metabolism].	3.14642e-169
NC_008149.1\|WP_002210304.1\|1232473_1234444_+\|5-dehydro-2-deoxygluconokinase	gnl\|CDD\|378281	pfam09863, DUF2090, Uncharacterized protein conserved in bacteria (DUF2090). This domain, found in various prokaryotic carbohydrate kinases, has no known function.	0
NC_008149.1\|WP_002209745.1\|1210480_1210726_+\|helix-turn-helix-domain-containing-protein	gnl\|CDD\|372675	pfam13693, HTH_35, Winged helix-turn-helix DNA-binding.	5.27401e-36
NC_008149.1\|WP_002213775.1\|1213496_1213955_+\|IS200/IS605-like-element-IS1541B-family-transposase	gnl\|CDD\|224854	COG1943, COG1943, Transposase and inactivated derivatives [DNA replication, recombination, and repair].	2.50747e-46
NC_008149.1\|WP_002210294.1\|1214069_1220048_-\|alpha-2-macroglobulin-family-protein	gnl\|CDD\|225248	COG2373, COG2373, Large extracellular alpha-helical protein [General function prediction only].	0

>NC_008149.1|WP_002223316.1|1220454_1221003_-|DUF1440-domain-containing-protein
MSEKRVNLQVIAWATIIGGFVSSLVKSGTEVNMPPRVVGEISPPAANIDAWLGWLGINSHSMDYVYQGVTISGAVVLYHWLFSFVFAFVYVLLSAYWPKVRLWYSAAYGLSITVAIHGVLIPALGFRHPAYLAGETGWLWNLNGYELWSEIIGHLCWSASLEICLVAVLAFFSKPIKGIWAN
>NC_008149.1|WP_002210294.1|1214069_1220048_-|alpha-2-macroglobulin-family-protein
MDLLRFLLISPFALIKGLYRLSAYLLRLVGRLLRPVVGNLNWRAPQWMTKTANGLHCAFNRSEQWVAKHPKGISAAIVLLMAAASAAFYGYHWYLNRPQPIEPAPMVYQETSIRVSAPRTVNYQAQKPEAQPLSLNFMHSAAPITAMGQVVDQGISLTPAIEGEWKWATERTLVFTPKKAWPMGANYQITIDTEKLLAPQIKLNQTELNFTTPAFAYQLEKAEYYQDPQEAQKRSTIFHVQFNAPVDVASFEKQILLGLVEGKSKSEKKLNFSVVYDEKKLNAWIHSQPLMPMDKGGSVHLSINKGVNASVAATPTTQAQNKWVSVPNLYSLAVNSINATLVESDNNNGERALIIAISDAVKDKEIKNAVKAWLLPQHNFQAKESAKTSTDFYPWDMDDIDDNLLQQSTPLALTLNEAEQEYQPIFSFKFDAPSYRTLLIEVNNSLTSVGGYKMPEKIYQIVRVPDYPKTLRFMSQGSLLSMQGDKQISVAARNMTGMKLDIKRVIPSQLQHIVSFKSSEYSSAHFNRLSDEYFTEHFQYQTALNNDNPGEINYQGVDLSRYLANNPSARRGVFLLTLSAWDPEKRDNQQHSEEDYDEDQEWVGDSRFVVITDLGIITKQSQDRSRDVFVQSIHSGLPAADAKVSVVAKNGVVLLSQITDSKGHVHFPALDAFKNERQPVMFLVEKEGDVSFLPTRATYDRNLDFSRFDIDGEETPSDPRTLSSYLFSDRGVYRPGDRFNIGLITRTANWATALDGVPLRAEIRDPRDTLMSTLPITLDSSGFNELSYTTGENSPTGEWNVYLYLVGKNNETSMLLGHTTVNVKEFEPDRLKVQLQLTPERQQGWVKPQELQANINVQNLFGTPAQERRVTSRLILRPMYPSFAPFPDYLFYENRHNSDGFETELEEQTTDLQGMATIPLDLKSYADATYQLQLLSEAFEAGGGRSVAATARVLVSPYDSLVGVKADGDLSYINRDAVRKLNIIAVDPSLNKIALPDLSLSLIEQKYISVLTKQDSGVYKYQSRLKEQLVSEQPLQISPTGTDFTLVTQQPGDFILVVKDSQGQVLNRISYTVAGNANLTRSLDRNTELKLKLNQAEYLQGEEIEIAINAPYAGSGLITIEKDKVYSWQWFHSDTTSSVQRIRIPPAMEGNGYINVQFVRDVNSDEIFMSPLSYGVMPFKISTKARQAAIELASPSVIKPGEVLPIKVTTDSPQRVVVFAVDEGILQVARYRLKDPLDYFFRKRELSVQSAQILDLILPEFSKLMALTSAPGGDAGEGLDLHLNPFKRKQDKPVAYWSGITEVNGETTFNYPIPDYFNGKIRVMAISATPDRIGKVQTSTTVRDNFILTPNVPAMVAPGDEFDVTVGVSNNLQGLKGKAVDITVRLTPPPQLEVVGEAQHSLSLAEKRETLVSFRLRARSALGDAPLVFDASYGSQSSRRTVSTSVRPAMPFRTQSVMGRMEGNKHTVTNLRQMFDNYAQRQATASHSPLVLTQGLARYLADYPYYSSEQIVSRSIPLIMQSKHPEMDSALNQNEVRDQLKNMLRILSSRQNSTGAIGLWHASPTPDPFVTPYVVQFLLEAKSAGYSLPNDILEGANNALRLLAARPYDDLYSLRLRAFAVYLLTLQGEITTNTLASVQSTLQQLYPDSWQTDLSAIYLASSYRLLKMDDEANKLLQPTWKQLGKAYSKAWWTQNYFDPLVQDATRLYLITRHFPEKVSSIPPQALENMVLALRDEHYTTYSSAMSILALESYTSQVAAQQDTPETLQIIEISKSKGIDPNVISTLNGLFVQGDFTGEAKAIQFNNYASAPAWYVVNQSGYDLQPPKDAISNGLEISRSYTDEQGKPVTQVTLGQKVNVHLKIRANAKQGQNNLAIVDLLPGGFEVVQQTAPEPEFYDNQDDQDEETGSGWQSPLMVSGSSWYPDYSDIREDRVIIYGSASTDVKEFIYQIKSTNTGRFVVPPAYGEAMYDRNVQALSVGKGHILVVPPEAK
>NC_008149.1|WP_002213775.1|1213496_1213955_+|IS200/IS605-like-element-IS1541B-family-transposase
MRDEKSLAHTRWNCKYHIVFAPKYRRQVFYREKRRAIGSILRKLCEWKNVNILEAECCVDHIHMLLEIPPKMSVSGFMGYLKGKSSLMLYEQFGDLKFKYRNREFWCRGYYVDTVGKNTARIQEYIKHQLEEDKMGEQLSIPYPGSPFTGRK
>NC_008149.1|WP_138921619.1|1210938_1213251_-|penicillin-binding-protein-1C
MALFLLALLVIGFRLWPHPPLSQGLPLSTAYYDRHGTLLRLSLANDDRYRLWTPLEEISPLVIQGIQLHEDRGFYYHPGVNPISLLRGFWQSYVQGGRQQGGSTLTMQLARMHWHLNTRSPTGKLRQIARAIQLELSYSKHDILEAYLNYAPYGRNIESIAAASLIYFDKKPQQLTLPEALTLAVLPQSPSYRIDPTTGVLGSALTQARNRLFVRWQQTYPTDSSQMALFQLPLSLRQPEKMPYIAPHFIEQIRRQNQQLANTQSQVDTTLDANLQQLVEKQVEAFIRRNNSRGIHNAAVLLLDTRDMGVRALVGSANYYDREIQGQVNGTNAKRSPGSTLKPFIYALGLEQGILHPMTILKDVPSSFGAYAPENFDHRFLGPVTATDALNFSRNIPAVYVASRLRQPTLYQFLRLSGVTNMASENHYGLSLVLGGGEITLQELARLYAMLANRGTLHPIQMVQTDKTLPSIRLLSEAASFITLDMLRQHRRPGDTLAQSPTSLPVYWKTGTSWGFRDAWSAGIFGPYVLIVWEGNFAGKGNSAFVGADAAAPLFFNIIDSIQANYPALREPKHPWPPQLKRVAICLASGNLPTPWCQQQGKTWFIPGKSPIKVDTVYRPVVIDINSGQAACLPYDRSQTRTEVFEFWPSDLANVFAQAGLPKRQPPDRSHCKEGNTLASGNAPRITSPLRNTTYTLRQSQQGRDQIVFSATLDADSTTTYWFVDDIYLGSSTSKKSIDWHPTRSGQYRIRAIDDHGRADSRLIRVEKVD
>NC_008149.1|WP_002209745.1|1210480_1210726_+|helix-turn-helix-domain-containing-protein
MDKQDWHPADILAGLKKRGTTMAALSRKSGLASSTLANTLLRPWPKGERLIAEVLELHPAEIWPSRYLKPKKSPAESVNPG
>NC_008149.1|WP_002209746.1|1208557_1208959_-|DUF1240-domain-containing-protein
MVKINRPLVGAFAILLFFLSSWGCWFSLSGYLAFFKLSDVIIFSWKVGFVIFAVPLLFYFSYLAFFSAIKNKPAIMNNKLANALAILAILGSIISLFSSAYISYSLTEYSYKSCPRSSWMSPNKYVKDIKLCP
>NC_008149.1|WP_002209748.1|1207923_1208325_-|DUF1240-domain-containing-protein
MVKINRPLFGAFAVFLLFLSCWVSWFSLNGYWDFFKLSDVIIFSWKVGVMIFGAPVLFYFSYLAFYCAIKNKPAKVNNKLANTFAMLAMLGVVISFFSSVYIGYSLTEYGYKLCSRSSWMSPNEYVKDIKLCP
>NC_008149.1|WP_002209749.1|1207339_1207912_+|Hcp-family-type-VI-secretion-system-effector
MSNLIYASVNGKKQGLISAGCSSLNSIGNRCQAGHEDQIQVLSLNHSISRQQNVAHHPVHFVKPIDKSSPLLGVAISENERINVVFYFYRVNSAGQLELYYEVKLTDASIVDITSVYPHSIDNNEMIPYEKIQLKYKSIAWDHKSAGTSGYSVWEDRVYSFLISSTLFQVCLNIFIFFNWLVYQNYFWEK
>NC_008149.1|WP_002227852.1|1207064_1207316_+|hypothetical-protein
MMKNNKNINKDEFSDKLSQQIKEMINNSQLDSVEILSVVMESIFSLFSETEGHLAEMKFIDSAGEDYRFILRLEVPPILERQH
>NC_008149.1|WP_002209751.1|1206786_1207026_+|hypothetical-protein
MEKEKKTLFGHKTPAMMQLSEQLESSLHNSPLVPEEKLALIMKLCVLLFRENKTDAAEMKVSDGRILKLTLEKTSSVLH
>NC_008149.1|WP_002210296.1|1221636_1222491_-|MurR/RpiR-family-transcriptional-regulator
MTTASNLSELQQQIRDRYDNLSKRLQQVSRYVLDNTNSVAFDTVAVIAERADVPPSTLIRFANAFDFSGFNEMKQLFRMNLVEETASYTDRARLFRAMESEAVPETPLGILQEFARSNAQALQQLAARTEPEMLQRAVELLAQADTIYVVGLRRSFSVAAYLTYALSHLECRPVQLHGLGGMLREQVNSIKARDIVVSISFSPYAEETVMVSEIAASAGARQIVITDSQISPLATFSDLCFVVKEAQVDAFRSQSATLCLVQSLVVALAYQQEAQAGAALAHRQ
>NC_008149.1|WP_002210297.1|1222828_1224355_+|CoA-acylating-methylmalonate-semialdehyde-dehydrogenase
METVANFINGKCVFSCGNSVTSGSPRAQAIFNSATGEPIRQVMMSTAQETEQAITAAQQAFASWSRQAPLKRARVMFRFKSLLEQHLDALAQLISEEHGKVYSDAVGELTRGLEVVEFACGIPHLQKGEHSANVGTGVDNHSLMQPLGVCVGITPFNFPAMVPMWMFPIALATGNTFVLKPSEKDPSLAVRLAQLLTEAGLPDGVFNVVQGDKTAVDVLLTDPRVQAVSFVGSTPIAEYIYQTASAHGKRCQALGGAKNHCILMPDADMDMAASAIMGAAYGAAGERCMALSVVLAVGDETADNLCARLEQQISTLRVGPGLAQEPENDMGPLISAPHRAKVLGYIDSGVAQKATLRIDGRGLKVAGHEQGYFVGPTLFDHVTPAMTIYQEEIFGPVLSVVRIADYRSAVDLINRHEYGNGTAIFTRDGGTARRFCEEVQVGMVGVNVPIPVPVAFHSFGGWKRSIFGPLNVHGNDGVRFYTRMKTITARWPEAQHDQGAAFSMPTLG
>NC_008149.1|WP_002359655.1|1224389_1226315_+|3D-(3,5/4)-trihydroxycyclohexane-1,2-dione-acylhydrolase-(decyclizing)
MKTVRMTMAQALVRFLNQQYVAIDGQEVAFVHGVMTIFGHGNVLGIGQALEENPGHLQVHQGCNEQGMAHMAIGFAKQYRRQRIYAVSSSIGPGAANMVTAAATATANRIPLLLLPGDIYASRQPDPVLQQIEQYHDLSISTNDCFRPVSRYWDRINRPEQLMSAMLSAMRVLTDPADTGAVTLCLPQDVQGEAWDYPASFFERRVHRIERRPPDTRRLSDALSLIARKRRPLVVCGGGVRYSGAHEAFRAFVENAQLPFTETQAGKGALPSDHPLNLGGIGVTGGLAANRLAPQADLVIGIGTRLTDFTTGSKALFSHPEVAFLLLNVAEFDALKLDATALIADARVGLEALTEGLAGYRTAWQGDIIEAKAAWCDECQRLWSRTWRPDEVPEVAGHLDDSLQEYAEVLNTTLTQTRVLGLINQHIEDDAIVVGAAGSLPGDLQRLWQVKTADTYHLEYGYSCMGYEIAAAIGAKIAMPHQPVYAMVGDGSYMMLHSELHTAVQEGLKITVLLFDNAGFGCINNLQMGHGMGSFCTESRHRNHESGQLNGPLICVDFAQNAESYGCRAWRVHDEPSLLAALAASRDHPGPVLLDIKVLPKSMTHDYASWWRTGDAQIARSPAVQQAAERTQMKVKRARQY
>NC_008149.1|WP_002210300.1|1227719_1228649_+|substrate-binding-domain-containing-protein
MKKLILAALIVFTSGVAFAENEQIVFSTPNLAMPFEVHMQRTAVKTAKALGVKLQVLDGQGSSPKQVADLENAITRGAQGFIVSPNDINAISSAVEEIQQAKLPVVTLDRSVESEKKVPHFGANNYKGGEAIANYVKSMFPNGAEIVLLTGQPGSSSNIERTKGIRDSLKTGGDKYRIVVDQTGNWMRSEGMRIIESVLPSLPKPPQVILSANDDMALGAIEALQSHGMKPGEIMVTGFDAVPEALARVREGWMAVTADQRPGYAVTTAMNQLVANIRDQKAITGADFLPTMITKENLDQAERVSEAGK
>NC_008149.1|WP_002223323.1|1228697_1230245_+|sugar-ABC-transporter-ATP-binding-protein
MSQPLLKITDMAKSFSGVWALSNVQLTLEQGEIHALLGENGAGKSTLLKALSGAQPQTHGEIWFNGEMLALDDSPVERQNKGIITIYQEVNLLPNMTVAENMFLGREPRRRQVFVDEKAVNQEAQAILDYLQLNVSPTTAVARLSIAQQQMVEIARALTLNAKLIVMDEPSAALSDSEVESLHRVVRELKGRGVSIIYVTHRLHEVFQLCDRFTVFQDGRYTGSDEVAGTNVEKIIRLMVGRDVVFNRRPASETHHQDQPIRLSVQGLCREKPPLDPHGVALKDISFHVHAGEVLGIAGLVGAGRTEVARCLFGAGAFTSGNFEIDGVPYQPRDPMFALEQGIALVPEDRKKEGAVQGLSIRDNLTLSSLAGLLQWRFFVNTRKEDQLIETYRLALQIKMVNSEQAVRKLSGGNQQKVILARCMALNPRILIVDEPTRGIDVGTKSEVHQVLFDMAKQGVAVIVISSDLPEVLAVSDRIITLSEGRVTGEIHGDDASEERLMTMMTINHNALNAA
>NC_008149.1|WP_002210302.1|1230256_1231285_+|ABC-transporter-permease
MLQPLSKPQASVKSAMRFDPITFFERFGVLIFMFLLLIFFQLQNSNFLSERNIFNILTEVSIYGIMAVGMTFVILTAGIDLSVGSILAVSAMTAAYVIKGDNFTTIDPNAWGGMSWLIGLSICLAMGTLIGFLQGLGVTRLRLPPFIVTLGGMTIWRGLTLVINDGAPIAGFDAGYRWWGRGDLLGISIPIWIFAIVAIAGYLALHKTRWGRFVYAIGGNPEAARLAGVNVKRVLVSVYVVIGCLAGLAGFILSARLGSAEAVAGISFELRVIASVVIGGTSLMGGYGRIGGTIIGSIIMGILINGLVLMNVSAYYQQIITGLIIVLAVAFDTYAKNRRGAL
>NC_008149.1|WP_002210303.1|1231308_1232442_+|Gfo/Idh/MocA-family-oxidoreductase
MKEVRIGLIGTGYIGKAHAIAYAQAPTVFELRGKLVREMVAEVSPALAAQRAQAFGFNRFTCDWRELVADPAIDVVDICSPNYLHKEMALAAIHHGKHVYAEKPLALNARDASEMAAAATRAGVKTLVGFNYIKNPSAKLAKEIIERGEIGEVIHFYGTHNEDYMADPNTPIHWHCLHATAGLGALGDLAAHIVSMAQYLVGEITQVCGDLKTVVVTRPASVGSSARVAVENEDQAHAMVRFVNGAQGVIEASRVACGRKMGLSYMITGTQGAISFTQERMAELKLYLHNDPVNRQGFRTLLVGPAHPEYAAFCMAAGHGIGFNDQKTVEVRDLIDGIAMDTPLWPDFAEGWKVSRILDAIALSHQDSRWVNVTDIV
>NC_008149.1|WP_002210304.1|1232473_1234444_+|5-dehydro-2-deoxygluconokinase
MSVEKQFSVSAEKTCNTENKCNTEKKFDVICMGRIAVDLYGQQIGARLEDVASFAKYLGGSSGNVAYGSARQGLRSSMLARVGDEHMGRFLREELHQVGCDTSHLTTDKKRLTALVLLSIKDRDTFPLIFYRDNCADMAITAQDFSEQYIASARSLAITGTHLSHPNTREAVLTALRYARRNGVRTVLDIDYRPVLWGLTSLGDGETRFIESHQVTAELLAVFNLFDVIVGTEEEFHIAGGSTNTLDALRGVREVSDAALVCKRGALGCSVYTEAIPQTLDEGLTVSGVRVKVLNVLGAGDAFMSGLLRGYLNDEGWPQACRYANACGALVVSRHGCAPAMPSKIELDNYLARADAVVRPDLDVHLNHLHRVTTRRRQWPELCVMAFDHRSQLEEMALQCGADLCHISTLKTLILQASREAVHTAGLQGKAGLLCDGTFGQDALNAITGAGWWIGRPIELPGSRPLAMEHGNIGSQLIGWPQEHIVKCLVFFHPEDAYSLRLEQEQKIIEVYRACCQSGHELLLEVILPAGMPRSDELYLRAISRFYNLGVYPDWWKLPPLASEGWAALNKLIERRDPHCRGVVILGLDASLEALRTGFNAAAGYPIVKGFAVGRTLFGDASLAWLKRDIDDTQLIARIRDNYLQLITLWRERGQK
>NC_008149.1|WP_002214721.1|1234458_1235517_+|myo-inosose-2-dehydratase
MTMVDQRTAVEPKTAVDQTTEVVRKAEVNQKIGIVRKIDIVRKTETVRKTEADRHTTAVQLGINPLTWTNDDLPSLGAETSLETCLSEGKEAGFAGFELGNKFSREAGVLGPILEHHQLKLVSGWYSGRLLERSVEEEIVAVRSHLALLRELGAKVMVFAEVSGCIHGEQQTPVHLRPRFPPARWAEYGAKLTAFARYTQALGVQIAYHHHMGTVIESAQDIDNLMIHTGEEVGLLLDTGHLTFAGADPLAVAQRWIARINHVHCKDVRTSVLADVKNRKTSFLDAVLSGVFTVPGDGGVDYPPIMALLKQHGYQGWLVVEAEQDPNVAHPMTYARMGYHNLSRLAHNAGLI
>NC_008149.1|WP_002210306.1|1235526_1236342_+|5-deoxy-glucuronate-isomerase
MSRLLSRRQAPDERGLTQRITPAQAGWGYVGFEVYELNEGQPLTLTAVPDERCLVLIAGRASISTPSAQFPNIGDRMSPFERHKPWAVYVTPGEAVQVQAITPLELAVCSAPGKGTYPTRLISPEDIGAEARGKGHNQRYVHNILPEDHPADSLLVVEVYTNEGASSSYPSHKHDTDNPPHETYLEETYYHRLNPEQGFCMQRVYTDDRSLDECMAVYNREVVMVPRGYHPVATMAGYDSYYLNVMAGPVRKWIFSWENDHVWINHNYPIT

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Crispr_ID: NC_008149_3

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_008149_3

2711070-2711279

Orphan

I-F

Consensus_repeat	Method
TTTCTAAGCTGCCTGTGCGGCAGTGAAC	CRISPRCasFinder
TTTCTAAGCTGCCTGTGCGGCAGTGAAC	CRT
AGGTTCACTGCCGCACAGGCAGCTTAGAAAAT	PILER-CR

3 spacers

DEDDh

The CRISPR arrays of NC_008149_3

>merge|NC_008149|3|2711070-2711279|CRISPRCasFinder,CRT,PILER-CR
TTATTGGGCTGCCTGTGCGGCAGTGAACGTTATACCCCGCGCAGGGAGTGAAGCGTTGACTTTCTAAGCTGCCTGTGCGGCAGTGAACTTAAGTTCTTTTTGTCAGCATCTTTAATAAATTTTCTAAGCTGCCTGTGCGGCAGTGAACCTGAAATACAAATAAAATAAATCGTCGAACATTTTCTAAGCTGCCTGTGCGGCAGTGAACGT

>NC_008149|3|3|2711070-2711277|CRISPRCasFinder
TTATTGGGCTGCCTGTGCGGCAGTGAAC	GTTATACCCCGCGCAGGGAGTGAAGCGTTGAC
TTTCTAAGCTGCCTGTGCGGCAGTGAAC	TTAAGTTCTTTTTGTCAGCATCTTTAATAAAT
TTTCTAAGCTGCCTGTGCGGCAGTGAAC	CTGAAATACAAATAAAATAAATCGTCGAACAT
TTTCTAAGCTGCCTGTGCGGCAGTGAAC

>NC_008149|3|2|2711070-2711277|CRT
TTATTGGGCTGCCTGTGCGGCAGTGAAC	GTTATACCCCGCGCAGGGAGTGAAGCGTTGAC
TTTCTAAGCTGCCTGTGCGGCAGTGAAC	TTAAGTTCTTTTTGTCAGCATCTTTAATAAAT
TTTCTAAGCTGCCTGTGCGGCAGTGAAC	CTGAAATACAAATAAAATAAATCGTCGAACAT
TTTCTAAGCTGCCTGTGCGGCAGTGAAC

>NC_008149|3|2|2711130-2711279|PILER-CR
TTTCTAAGCTGCCTGTGCGGCAGTGAACTTAA	GTTCTTTTTGTCAGCATCTTTAATAAAT
TTTCTAAGCTGCCTGTGCGGCAGTGAACCTGA	AATACAAATAAAATAAATCGTCGAACAT
TTTCTAAGCTGCCTGTGCGGCAGTGAACGT

Protein	Signature genes	Signature genes Name	Protein_function
NC_008149.1\|WP_002211916.1\|2697939_2698782_-\|fumarylacetoacetate-hydrolase-family-protein	unknown	unknown	gnl\|CDD\|223257
NC_008149.1\|WP_002217522.1\|2707451_2707769_-\|DUF496-family-protein	unknown	unknown	gnl\|CDD\|180070
NC_008149.1\|WP_002211912.1\|2699997_2700420_+\|thiol-disulfide-oxidoreductase-DCC-family-protein	unknown	unknown	gnl\|CDD\|225556
NC_008149.1\|WP_002209743.1\|2705872_2707081_-\|IS256-family-transposase	unknown	unknown	gnl\|CDD\|225865
NC_008149.1\|WP_190947800.1\|2717796_2717910_+\|gluconate-5-dehydrogenase	unknown	unknown	unknown
NC_008149.1\|WP_002231208.1\|2719568_2719616_+\|his-operon-leader-peptide	unknown	unknown	unknown
NC_008149.1\|WP_002216393.1\|2698829_2699570_-\|SDR-family-oxidoreductase	unknown	unknown	gnl\|CDD\|187626
NC_008149.1\|WP_002211902.1\|2711771_2713163_-\|APC-family-permease	unknown	unknown	gnl\|CDD\|223605
NC_008149.1\|WP_002211905.1\|2708202_2709312_-\|SDR-family-oxidoreductase	unknown	unknown	gnl\|CDD\|187547
NC_008149.1\|WP_002216311.1\|2714999_2715893_+\|sugar-ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|224053
NC_008149.1\|WP_002211900.1\|2716536_2717532_+\|ABC-transporter-permease	unknown	unknown	gnl\|CDD\|224093
NC_008149.1\|WP_157131899.1\|2717920_2718211_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|374732
NC_008149.1\|WP_002216388.1\|2702757_2705910_+\|inverse-autotransporter-beta-barrel-domain-containing-protein	unknown	unknown	gnl\|CDD\|378762
NC_008149.1\|WP_002211917.1\|2696630_2697908_-\|L-fuconate-dehydratase	unknown	unknown	gnl\|CDD\|239440
NC_008149.1\|WP_002216312.1\|2713622_2714714_-\|oxidoreductase	unknown	unknown	gnl\|CDD\|182570
NC_008149.1\|WP_002211911.1\|2700428_2701733_-\|MFS-transporter	unknown	unknown	gnl\|CDD\|340877
NC_008149.1\|WP_002216310.1\|2715850_2716540_+\|sugar-ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|224053
NC_008149.1\|WP_002211896.1\|2719898_2720798_+\|ATP-phosphoribosyltransferase	unknown	unknown	gnl\|CDD\|234781
NC_008149.1\|WP_002228562.1\|2709604_2711035_+\|exodeoxyribonuclease-I	DEDDh	cd06127_DEDDh_CAS-I	gnl\|CDD\|236979
NC_008149.1\|WP_002211898.1\|2718365_2719193_-\|SDR-family-oxidoreductase	unknown	unknown	gnl\|CDD\|187576

Protein	Function_ID	Function_description	E-value
NC_008149.1\|WP_002211916.1\|2697939_2698782_-\|fumarylacetoacetate-hydrolase-family-protein	gnl\|CDD\|223257	COG0179, MhpD, 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway) [Secondary metabolites biosynthesis, transport, and catabolism].	8.96038e-107
NC_008149.1\|WP_002217522.1\|2707451_2707769_-\|DUF496-family-protein	gnl\|CDD\|180070	PRK05423, PRK05423, DUF496 family protein.	5.26004e-59
NC_008149.1\|WP_002211912.1\|2699997_2700420_+\|thiol-disulfide-oxidoreductase-DCC-family-protein	gnl\|CDD\|225556	COG3011, COG3011, Predicted thiol-disulfide oxidoreductase [General function prediction only].	5.0494e-57
NC_008149.1\|WP_002209743.1\|2705872_2707081_-\|IS256-family-transposase	gnl\|CDD\|225865	COG3328, COG3328, Transposase and inactivated derivatives [DNA replication, recombination, and repair].	1.39969e-152
NC_008149.1\|WP_002216393.1\|2698829_2699570_-\|SDR-family-oxidoreductase	gnl\|CDD\|187626	cd05368, DHRS6_like_SDR_c, human DHRS6-like, classical (c) SDRs. Human DHRS6, and similar proteins. These proteins are classical SDRs, with a canonical active site tetrad and a close match to the typical Gly-rich NAD-binding motif. Human DHRS6 is a cytosolic type 2 (R)-hydroxybutyrate dehydrogenase, which catalyses the conversion of (R)-hydroxybutyrate to acetoacetate. Also included in this subgroup is Escherichia coli UcpA (upstream cys P). Classical SDRs are typically about 250 residues long, while extended SDRs are approximately 350 residues. Sequence identity between different SDR enzymes are typically in the 15-30% range, but the enzymes share the Rossmann fold NAD-binding motif and characteristic NAD-binding and catalytic sequence patterns. These enzymes catalyze a wide range of activities including the metabolism of steroids, cofactors, carbohydrates, lipids, aromatic compounds, and amino acids, and act in redox sensing. Classical SDRs have an TGXXX[AG]XG cofactor binding motif and a YXXXK active site motif, with the Tyr residue of the active site motif serving as a critical catalytic residue (Tyr-151, human 15-hydroxyprostaglandin dehydrogenase (15-PGDH) numbering). In addition to the Tyr and Lys, there is often an upstream Ser (Ser-138, 15-PGDH numbering) and/or an Asn (Asn-107, 15-PGDH numbering) contributing to the active site; while substrate binding is in the C-terminal region, which determines specificity. The standard reaction mechanism is a 4-pro-S hydride transfer and proton relay involving the conserved Tyr and Lys, a water molecule stabilized by Asn, and nicotinamide. Extended SDRs have additional elements in the C-terminal region, and typically have a TGXXGXXG cofactor binding motif. Complex (multidomain) SDRs such as ketoreductase domains of fatty acid synthase have a GGXGXXG NAD(P)-binding motif and an altered active site motif (YXXXN). Fungal type ketoacyl reductases have a TGXXXGX(1-2)G NAD(P)-binding motif. Some atypical SDRs have lost catalytic activity and/or have an unusual NAD(P)-binding motif and missing or unusual active site residues. Reactions catalyzed within the SDR family include isomerization, decarboxylation, epimerization, C=N bond reduction, dehydratase activity, dehalogenation, Enoyl-CoA reduction, and carbonyl-alcohol oxidoreduction. Note: removed : needed to make this chiodl smaller when drew final trees: rmeoved text form description: Other proteins in this subgroup include Thermoplasma acidophilum aldohexose dehydrogenase, which has high dehydrogenase activity against D-mannose, Bacillus subtilis BacC involved in the biosynthesis of the dipeptide bacilysin and its antibiotic moiety anticapsin, Sphingomonas paucimobilis strain B90 LinC, involved in the degradation of hexachlorocyclohexane isomers...... P).	1.05065e-117
NC_008149.1\|WP_002211902.1\|2711771_2713163_-\|APC-family-permease	gnl\|CDD\|223605	COG0531, PotE, Amino acid transporters [Amino acid transport and metabolism].	3.72025e-45
NC_008149.1\|WP_002211905.1\|2708202_2709312_-\|SDR-family-oxidoreductase	gnl\|CDD\|187547	cd05236, FAR-N_SDR_e, fatty acyl CoA reductases (FARs), extended (e) SDRs. SDRs are Rossmann-fold NAD(P)H-binding proteins, many of which may function as fatty acyl CoA reductases (FAR), acting on medium and long chain fatty acids, and have been reported to be involved in diverse processes such as biosynthesis of insect pheromones, plant cuticular wax production, and mammalian wax biosynthesis. In Arabidopsis thaliana, proteins with this particular architecture have also been identified as the MALE STERILITY 2 (MS2) gene product, which is implicated in male gametogenesis. Mutations in MS2 inhibit the synthesis of exine (sporopollenin), rendering plants unable to reduce pollen wall fatty acids to corresponding alcohols. This N-terminal domain shares the catalytic triad (but not the upstream Asn) and characteristic NADP-binding motif of the extended SDR family. Extended SDRs are distinct from classical SDRs. In addition to the Rossmann fold (alpha/beta folding pattern with a central beta-sheet) core region typical of all SDRs, extended SDRs have a less conserved C-terminal extension of approximately 100 amino acids. Extended SDRs are a diverse collection of proteins, and include isomerases, epimerases, oxidoreductases, and lyases; they typically have a TGXXGXXG cofactor binding motif. SDRs are a functionally diverse family of oxidoreductases that have a single domain with a structurally conserved Rossmann fold, an NAD(P)(H)-binding region, and a structurally diverse C-terminal region. Sequence identity between different SDR enzymes is typically in the 15-30% range; they catalyze a wide range of activities including the metabolism of steroids, cofactors, carbohydrates, lipids, aromatic compounds, and amino acids, and act in redox sensing. Classical SDRs have an TGXXX[AG]XG cofactor binding motif and a YXXXK active site motif, with the Tyr residue of the active site motif serving as a critical catalytic residue (Tyr-151, human 15-hydroxyprostaglandin dehydrogenase numbering). In addition to the Tyr and Lys, there is often an upstream Ser and/or an Asn, contributing to the active site; while substrate binding is in the C-terminal region, which determines specificity. The standard reaction mechanism is a 4-pro-S hydride transfer and proton relay involving the conserved Tyr and Lys, a water molecule stabilized by Asn, and nicotinamide. Atypical SDRs generally lack the catalytic residues characteristic of the SDRs, and their glycine-rich NAD(P)-binding motif is often different from the forms normally seen in classical or extended SDRs. Complex (multidomain) SDRs such as ketoreductase domains of fatty acid synthase have a GGXGXXG NAD(P)-binding motif and an altered active site motif (YXXXN). Fungal type ketoacyl reductases have a TGXXXGX(1-2)G NAD(P)-binding motif.	1.89947e-61
NC_008149.1\|WP_002216311.1\|2714999_2715893_+\|sugar-ABC-transporter-ATP-binding-protein	gnl\|CDD\|224053	COG1129, MglA, ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism].	3.90601e-98
NC_008149.1\|WP_002211900.1\|2716536_2717532_+\|ABC-transporter-permease	gnl\|CDD\|224093	COG1172, AraH, Ribose/xylose/arabinose/galactoside ABC-type transport systems, permease components [Carbohydrate transport and metabolism].	1.22935e-72
NC_008149.1\|WP_157131899.1\|2717920_2718211_+\|hypothetical-protein	gnl\|CDD\|374732	pfam16695, Tai4, Type VI secretion system (T6SS), amidase immunity protein. Tai4 is a new form of autoimmunity protein for a type VI secretion system, T6SS. T6SS has roles in interspecies interactions, as well as higher order host-infection, by injecting effector proteins into the periplasmic compartment of the recipient cells of closely related species. Pseudomonas aeruginosa produces at least three effector proteins to other cells and thus has three specific cognate immunity proteins to protect itself. Tae4, or type VI amidase effector 4, in Enterobacter cloacae has a cognate Tai4 or type VI amidase immunity 4 protein. The effector is Tae4, pfam14113.	4.0065e-14
NC_008149.1\|WP_002216388.1\|2702757_2705910_+\|inverse-autotransporter-beta-barrel-domain-containing-protein	gnl\|CDD\|378762	pfam11924, IAT_beta, Inverse autotransporter, beta-domain. This is a family of beta-barrel porin-like outer membrane proteins from enteropathogenic Gram-negative bacteria. Intimins and invasins are virulence factors produced by pathogenic Gram-negative bacteria. They carry C-terminal extracellular passenger domains that are involved in adhesion to host cells and N-terminal beta domains that are embedded in the outer membrane. This family represents the beta-barrel porin-like domain in the outer membrane that can be found in intimins, invasins and some inverse autotransporters.	1.47456e-126
NC_008149.1\|WP_002211917.1\|2696630_2697908_-\|L-fuconate-dehydratase	gnl\|CDD\|239440	cd03324, rTSbeta_L-fuconate_dehydratase, Human rTS beta is encoded by the rTS gene which, through alternative RNA splicing, also encodes rTS alpha whose mRNA is complementary to thymidylate synthase mRNA. rTS beta expression is associated with the production of small molecules that appear to mediate the down-regulation of thymidylate synthase protein by a novel intercellular signaling mechanism. A member of this family, from Xanthomonas, has been characterized to be a L-fuconate dehydratase. rTS beta belongs to the enolase superfamily of enzymes, characterized by the presence of an enolate anion intermediate which is generated by abstraction of the alpha-proton of the carboxylate substrate by an active site residue and is stabilized by coordination to the essential Mg2+ ion.	0
NC_008149.1\|WP_002216312.1\|2713622_2714714_-\|oxidoreductase	gnl\|CDD\|182570	PRK10586, PRK10586, putative oxidoreductase; Provisional.	0
NC_008149.1\|WP_002211911.1\|2700428_2701733_-\|MFS-transporter	gnl\|CDD\|340877	cd17319, MFS_ExuT_GudP_like, Hexuronate transporter, Glucarate transporter, and similar transporters of the Major Facilitator Superfamily. This family is composed of predominantly bacterial transporters for hexuronate (ExuT), glucarate (GudP), galactarate (GarP), and galactonate (DgoT). They mediate the uptake of these compounds into the cell. They belong to the Major Facilitator Superfamily (MFS) of membrane transport proteins, which are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	1.17308e-74
NC_008149.1\|WP_002216310.1\|2715850_2716540_+\|sugar-ABC-transporter-ATP-binding-protein	gnl\|CDD\|224053	COG1129, MglA, ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism].	1.76633e-90
NC_008149.1\|WP_002211896.1\|2719898_2720798_+\|ATP-phosphoribosyltransferase	gnl\|CDD\|234781	PRK00489, hisG, ATP phosphoribosyltransferase; Reviewed.	6.63843e-161
NC_008149.1\|WP_002228562.1\|2709604_2711035_+\|exodeoxyribonuclease-I	gnl\|CDD\|236979	PRK11779, sbcB, exonuclease I; Provisional.	0
NC_008149.1\|WP_002211898.1\|2718365_2719193_-\|SDR-family-oxidoreductase	gnl\|CDD\|187576	cd05266, SDR_a4, atypical (a) SDRs, subgroup 4. Atypical SDRs in this subgroup are poorly defined, one member is identified as a putative NAD-dependent epimerase/dehydratase. Atypical SDRs are distinct from classical SDRs. Members of this subgroup have a glycine-rich NAD(P)-binding motif that is related to, but is different from, the archetypical SDRs, GXGXXG. This subgroup also lacks most of the characteristic active site residues of the SDRs; however, the upstream Ser is present at the usual place, and some potential catalytic residues are present in place of the usual YXXXK active site motif. Atypical SDRs generally lack the catalytic residues characteristic of the SDRs, and their glycine-rich NAD(P)-binding motif is often different from the forms normally seen in classical or extended SDRs. Atypical SDRs include biliverdin IX beta reductase (BVR-B,aka flavin reductase), NMRa (a negative transcriptional regulator of various fungi), progesterone 5-beta-reductase like proteins, phenylcoumaran benzylic ether and pinoresinol-lariciresinol reductases, phenylpropene synthases, eugenol synthase, triphenylmethane reductase, isoflavone reductases, and others. SDRs are a functionally diverse family of oxidoreductases that have a single domain with a structurally conserved Rossmann fold, an NAD(P)(H)-binding region, and a structurally diverse C-terminal region. Sequence identity between different SDR enzymes is typically in the 15-30% range; they catalyze a wide range of activities including the metabolism of steroids, cofactors, carbohydrates, lipids, aromatic compounds, and amino acids, and act in redox sensing. Classical SDRs have an TGXXX[AG]XG cofactor binding motif and a YXXXK active site motif, with the Tyr residue of the active site motif serving as a critical catalytic residue (Tyr-151, human 15-hydroxyprostaglandin dehydrogenase numbering). In addition to the Tyr and Lys, there is often an upstream Ser and/or an Asn, contributing to the active site; while substrate binding is in the C-terminal region, which determines specificity. The standard reaction mechanism is a 4-pro-S hydride transfer and proton relay involving the conserved Tyr and Lys, a water molecule stabilized by Asn, and nicotinamide. In addition to the Rossmann fold core region typical of all SDRs, extended SDRs have a less conserved C-terminal extension of approximately 100 amino acids, and typically have a TGXXGXXG cofactor binding motif. Complex (multidomain) SDRs such as ketoreductase domains of fatty acid synthase have a GGXGXXG NAD(P)-binding motif and an altered active site motif (YXXXN). Fungal type ketoacyl reductases have a TGXXXGX(1-2)G NAD(P)-binding motif.	2.54107e-68

>NC_008149.1|WP_002228562.1|2709604_2711035_+|exodeoxyribonuclease-I
MSDKNKQPTFYVHDYETFGQRPALDRPAQFAGVRTDLDFNLVEEPLVIYCKPADDYLPQPEAVMITGITPQHALANGVNEAEFSRQIHQAFSVPGTCILGYNNIRFDDEVSRNIFYRNFYDPYAYSWQGGNSRWDLLDVMRACYALRPEGIVWPENDDGLPSFKLEHLTKANGVEHLQAHDAMSDVYATIAMAKLVKQAQPRLFDYLYQHRSKHKINALIDIAEMTPLVHVSGMFGAARGNTSWVAPLAWHPENKNAVIMCDLAGDMSPLLELDSDTLRERLYTRRDKLQAQESAIPIKLVHINKCPVLAPAKTLLPENADRLGIDRQRCLQNLQLLRQNPQVREKVVALFAQAEPFAVTDDVDTQLYNGFFSDADRATIKIIQQTESQNLPALDLTFQDPRLEALLFRFRARNYPNTLNDSEQQRWLQHRREALSPERVQDYVLQLEQFYNQYEDDKEKLTLLKALFEYAKGLVS
>NC_008149.1|WP_002211905.1|2708202_2709312_-|SDR-family-oxidoreductase
MKKLLLTGATGFLGGAVLEKLLLASSDFNYLLLVRANTPEQGLMRIRENLEKFYLPNELINKININHVLLGDLAEPDSFINDVRIDDVTHVINCAAIASFGNNPLIWKVNVEGTLAFGKRMAQVAGLQRFVHVGTAMACTPEADTVVDERVLSTENDAHLVEYTKSKSAIECLLAEHCPTLPLVFARPSIVVGHTRLGCQPSSSIFWVFRMALMLRKFMCSLDDHIDVIPVDYCADALLYILEYPNLPDDIYHISAGEKGSVSFSEIDQAMSVAAKQKPVGVNYSQVEYTALVQMRNQLKGIFGPCNERLMLKAMRLYGSFAMLNVRFSNERLLSLGMPRTPRFTDYIARCVESSHGMTIQQQMAVDFK
>NC_008149.1|WP_002217522.1|2707451_2707769_-|DUF496-family-protein
MDNASKPTFQDVLEFVRMFRRKNKLQREIVDNEKKIRDNQKRVLLLDNLSEYIKPGMSIEEVQAIIANMRGDYEDRVDDYIIKNADLSKERRELSKKLKAMGEVK
>NC_008149.1|WP_002209743.1|2705872_2707081_-|IS256-family-transposase
MDEKKLKALAAELAKGLKTEADLNAFSRMLTKLTVETALNAELTEHLGHEKNTPKSGSNTRNGYSSKTLLCDDGEIELNTPRDRENTFEPQLIKKNQTRITQMDSQILSLYAKGMTTREIVATFKEMYDADVSPTLISKVTDAVKEQVAEWQNRQLDALYPIVYMDCIVVKVRQNGSVINKAVFLALGINTEGQKELLGMWLAENEGAKFWLSVLTELKNRGLQDILIACVDGLKGFPDAINSVYPQTHIQLCIIHMVRNSLKYVSWKDYKAVTSGLKMVYQAPTEEAALMALDKFAEAWDDKYPQISKSWRTHWENLNTFFGYPPDIRKAIYTTNAIESVNSVIRAAIKKRKVFPTDDSVRKVVYLAIKDASKKWSMPIQNWRLAMSRFIIEFGDRLSDHL
>NC_008149.1|WP_002216388.1|2702757_2705910_+|inverse-autotransporter-beta-barrel-domain-containing-protein
MSLYRISSLHQAKQLNKNKQLNKTRISKSVVWANIVIQAIFPLSIAFTPAVMAAETVGASDEKPRSASQAEQSTANAATRLASILTNDDSAKQASSIARGTAANAGNEALQKWFNQFGSAKVQLNLDEKLSLKGSQLDVLLPLTDSPDLLTFTQLGGRYIDDRVTLNVGLGQRHFFAQQMLGYNLFIDHDASYSHTRIGVGAEYGRDFINLAANGYFGVSGWKNSPDLDKYDEKVANGFDLRSEAYLPTLPQLGGKLIYEQYFGDEVGLFGVDNRQKNPLAVTLGVNYTPIPLFTVGVDHKMGRAGMNDTRFNLGFNYAFGTPLTHQLDSDAVAIKRSLMGSRYNLVDRNNQIVMKYRKQNRVTLELPARVSGAARQTMPLVANATAQQGIDRLEWEASALTLAGGKITGSGNNWQITLPSYLSGGEGNNTYRISAIAYDTLGNASPVAYSDLVVDSHGVNTNASGLTAAPEILPANASASSVIEFNIKDNANQPITGIADELAFSLELVELPEELAKAKARSVPLKTVSHTLTKITESAPGIYQATLTSGSKPQLINITAQINGVPLADVQTKVTLIADESTATLQTSSLQIITNGSLADDTDANQIRAVVVDAYGNKLSGVQVNFTVGNNAKITETTLSDKQGGVTAAITSTKAGTYTVTAELNGVTQQIDVNFIPDAGTATLDDSDEYKLQWVTNGQVADGESTNSVQLTVVDKFGNTVPGVDVAFTTDIGAIISEVTPTDANGVATAKIISSQAKSHTVKATLNRKEQTVEVNFIADTATAEITANNFTVEVDGQVAGSGTNQVQALVVDKKGNPVANMTVNFTATNGVVVETTSAKTDENGKVTTNLSMTNVGGTISTVTATMINSANVTSTQDKPVIFYPDFTKATLNTPANTYSGFNINSGFPTTGFKNTHFQLSPHGITGANSDYDWVSSHPNVSVSNTGAITLQDNPGGKVTITATWKHDSSKVFTYDFTLNYWVGLYSSTNLSWAQANASCINAGMRLPTNREVSAGQDVRGVGSLLSLSIILCNCHRIKGDRSGGHRTR
>NC_008149.1|WP_002211911.1|2700428_2701733_-|MFS-transporter
MSNFNHYPDPTLNSAIKKAWYRLMPLMFIMYFVAFIDRINVGFAKDAMSADIGLSQSAFALGAGIFFAAYALFGIPANLMMNKLGAKVWLSSTTVVWGLLSAGTGLVSNEYQFVILRFLLGVAEAGFYPGILLLASIYFPNKIRASVIGIFVLGVPAALTLGSPISGALLDMQGFLGQPGWFWMFLLEGLPAVGLGIFAFFYLDDSPATARYLNPEEKQALLTQLSIEQSDTESSSVKAVLLSPKVWHLALIYGTIQVGVYGLIFFLPSQVATLLGSTLGFKESLVAAIPWAFSALGVYYIPRYADRKTHRRNPIATLNLVVAAIGLIISAYASPVLAIAALCLCAIGFLAVQPIFWTFPAQILSGKALAAGIGFCTTMGAFFSFLAPIIRVEAESQFNSPPAGLITLALFSLLSATLIFSLKFWPAKATAEVI
>NC_008149.1|WP_002211912.1|2699997_2700420_+|thiol-disulfide-oxidoreductase-DCC-family-protein
MSAPLPYIKPGERVIIYDGVCALCTGWVNFLIRHDRRHTVRLSAVQSKKGHALLEWAGLPTDKINTLVLIENQQVYLRSEAIFRVIANLPWPWRILGVLRIFPRPLRDRCYDGIALNRYRLFGRYDAVRKLKADHERRFL
>NC_008149.1|WP_002216393.1|2698829_2699570_-|SDR-family-oxidoreductase
MNLKGKKALVTAAGQGIGFNTATLFARKGAEVIASDINIAALSNIPGITAVSLDVTDTLAINDVAQAIGPIDVLFNCAGVVHSGDILTCSEQEWQFALDLNVTAMFHMIRAFLPGMIACQQGSIINMSSVASSIKGVPNRFAYSTSKAAVIGLTRSVAADYVTQGIRCNAICPGTVESPSLRQRIAVQAHAEGRSEADVFQAFAARQPIGRIGKAEEIAQLALYLASDASAYTTGTIHIIDGGWSN
>NC_008149.1|WP_002211916.1|2697939_2698782_-|fumarylacetoacetate-hydrolase-family-protein
MKLLRYGPVGEERPALLDELGEIRDLSAHIEDISGKFLLPATLYKLRQLDSASLPLVRGEQRLGACVGHVGKFICVGLNYADHAAETGAEIPQEPVIFNKWTSAIIGPNDDIEIPRNSVKTDWEVELGVVIGTGGRYIGEANAMSYVAGYCVVNDISEREFQLEHGGTWDKGKGCDTFGPIGPWLVTRDEIPDPHQLGLWLDVDGRRYQNGSTRTMIFKIPQIISYLSRFMSLQSGDVISTGTPPGVGLGQKPPVYLHAGQIMRLGIEGLGEQCQKTIQA
>NC_008149.1|WP_002211917.1|2696630_2697908_-|L-fuconate-dehydratase
MTIITALRTEDVRFPTSLELDGSDAMNPDPDYSAAYVILDTDNPALSGHGLTFTIGRGNEICCVAIHALEHLIVGRDLASMTANMGKFWREFTSDSQLRWIGPEKGAIHLATGAVINAVWDLWSKAEGKPLWRLVADMSPEELVRCIDFRYITDCITPEEALTLLQQRAHNKALRLEKLQDEGYPCYTTSAGWLGYPDDKLRRLCQDAVDAGFDYLKLKVGRDLEDDIRRVRITREVLGPDRKLMIDANQIWETNEAIPWVNQLAFANPWFIEEPTNPDDIEGHRRIRQGVAPVKVATGEMCQNRIMFKQFIMREAIDVVQIDACRLGGVNEVLAVMLMAAKYDLPVCPHAGGVGLCEYVQHLAMIDYLCIAGTDKGRVIEYVDHLHEHFVHPCVIKNAAYMPPEQPGFSIEMHQSSIEKYRFRV
>NC_008149.1|WP_002211902.1|2711771_2713163_-|APC-family-permease
MAHDATVAVGTNQTGTNNRVQLRKTLTLVQVVMMGLAYLQPMTIFDTFGIVSGLTDGHVATSYAIALIAVLFTAVSYGKLVKRFPSAGSAYTYAQKSISPNVGFMVGWSSLLDYLFMPMINILLAKIYLEAIFPGVPSWIFVGALVSLMTLFNLRGINIVANLNSVIVVVQVAIMVVFMGLLIHGVYQGEGAGTLVSARPFYSENAHLVPMITGATILCFSFLGFDGISSLSEETPNAGKVIPKAIFLTALIGGIIFIAVSYCLQLYFPDISRFTDPEASQPEIMLFVAGKFFQSVILCFSCVTVLASGMAAHAGVSRLLYVMGRDGVFPEKVFGYVHPKWRTPAINVLLVGGVALSAISFDLVTATALINFGALVAFTFVNLSVIAQFYVRERRNSTFKDHFNYLILPMIGAGTVGVLWVNLESSSMTLGLVWGAIGLSYMVWKTRAFRRALPQFTEEPAQL
>NC_008149.1|WP_002216312.1|2713622_2714714_-|oxidoreductase
MSANAIRVQVGPANYFSFPGAIDKLSEFYPQAALDKALWIYGERALAAAQDYLPKAFHGPQAVRAKFSTHCSQSTVADLVSAAGGDRQVVIGIGGGAVLDTAKVVARQLGVPLVAIPTIAATCAAWTPLSVWYNEAGQALNFEIFNDANHLVLVEPRIMLHAPVEYLLAGIGDTLAKWYEAVVLSPQPETLSLTVRLGLQAALEIRNVLLKQSEAALQAVAQGELTQDFLDVVDAIIAGGGMVGGLGERYTRVAAAHAVHNGLTLLPQTEHFLHGTKVAYGILVQTALLGQDEVLRSLIVAFNQLGLPTHLAALDVDINDREAIDRVIGRILKPGESIHYLPIALNSEKVWAAIEQVEIAAQH
>NC_008149.1|WP_002216311.1|2714999_2715893_+|sugar-ABC-transporter-ATP-binding-protein
MSSIPPSRLEMRNISISFSGFHALQEVDFTLEGGSTHALIGANGAGKSTLMAILSGAHNHYRGEIFIDGQPIDIHSPRQARQHGIHVVQQEVDVALIPTLSVAENIMLDELADRGHLFNWPQLYRQAEALLEQLELKLNVRQRLESCTLAEKQQVLLARALSHQCRFLILDEPTAPLDQEESARLFRVVRRLQSEGIGIVFISHRIHELREVCDQLTVLRDGRRVSHDTMEGMSGEQIVEKMLGHTLEDISPLGERQSAAKHGCRKHYCRKHCYRSAAYMISISCAISPSHYIRAKF
>NC_008149.1|WP_002216310.1|2715850_2716540_+|sugar-ABC-transporter-ATP-binding-protein
MRDISLTLHQGEILGIAGLAGAGKTELCKALFGDTPSTLERGELSGKAWRPRSPDRSVAQGLALVPEERRKEGIFIDEGIPMNLSVAADDSFSRWSLFSRRQELSWAKELIERLGIRTSSPQQKLAHLSGGNQQKVAIGKWLRGDAQVLIFDEPTKGVDIKAKQDLFSLIDQLAQQGKGIIYASGEFSELVGLCDRICVLWDGRIVAELNAAEVDEETLLLFSTGGTPQ
>NC_008149.1|WP_002211900.1|2716536_2717532_+|ABC-transporter-permease
MSKELPLPDVQPWRHQLFDFLYKWGMLLTVVALIALFGLASDNFLDPNNIINILRSIAIVTVIAIGVSISLSIGGFDLSVGSTASLANAVVVSLFVWYGFGTTGAIILTLLICTLVGLFNAFLIVVLKIPDMLATLASLFVIQGVAMTYSRGGSITQSMLLPSGDMAEGVIPEIFSALGQVPVIVLIMLAVTVVVQLYLSLTKHGRRMYAIGGNPQAARLAGIRTVRYRVLAYVLSAQLAALGGILLASRIGSSQVNAGSGYLMDAVAAAYIGFSLAGSGKPNAFGTLIGAIILGVLQNGLVMLSVPYYAMDIIKGLVLAMALALTYIQKR
>NC_008149.1|WP_190947800.1|2717796_2717910_+|gluconate-5-dehydrogenase
MDVFTASLRSACSLRRGHFVNNLTYLFNFFLYSCSRS
>NC_008149.1|WP_157131899.1|2717920_2718211_+|hypothetical-protein
MQQKNNLENFALSICLAEGFPDGEINSEAFSAVGAYVELGAYPVEAYEEVSELAKKFLEKKYISKNGESKLTVMKCIDLSQSSELSAIKDKYTRHI
>NC_008149.1|WP_002211898.1|2718365_2719193_-|SDR-family-oxidoreductase
MKKVAIIGLGWLGMPLAQSLSRRGIDVVGSKTTPDGVDAARMSGINCYPLVLTPELICEPDDLAQLMAVDALVITLPASRTTAGGDHYFQAVQQVVDSALAFGVPRIIFTSSTSVYGETRGRIKESSPLQPVTVAGKTLMALEQWLHQLPHTSVDILRLAGLVGTDRHPGRFLAGKTGVKGGSQGVNLVHQEDVIAAIELLLNRPKGGHLYNLCAPIHPRKRDFYPACARALQLTPPEFAVEEQEGANREIDGSKICSELGFEYLYPDPSRMPLN
>NC_008149.1|WP_002231208.1|2719568_2719616_+|his-operon-leader-peptide
MNRVQFNHHHHHHPD
>NC_008149.1|WP_002211896.1|2719898_2720798_+|ATP-phosphoribosyltransferase
MLDKTRLRIAMQKSGRLSDESQELLSRCGIKINLQQQRLIAFAENMPIDILRVRDDDIPGLVMDGVVDLGIIGENVLEEELLNRRAQGDDPRYFTLRRLDFGGCRLSLAAPLDAEYTGPQCLQDTRIATSYPHILKQYLDKQGVRFKSCLLNGSVEVAPRAGLADAICDLVSTGATLEANGLREVEVIYRSKACLIQRDGEMSVDKQQLIDRLMTRIQGVIQARESKYIMMHAPSERLDEIITLLPGAERPTILPLAGDKSRVAMHMVSSETLFWETMEKLKALGASSILVLPIEKMME

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Crispr_ID: NC_008149_4

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_008149_4

2836931-2837052

Orphan

Consensus_repeat	Method
CAATTGATTATATCGATTAATATTGGCATTAAG	CRISPRCasFinder

1 spacers

The CRISPR arrays of NC_008149_4

>merge|NC_008149|4|2836931-2837052|CRISPRCasFinder
CAATTGATTATATCGATTAATATTGGCATTAAGAGATTTAATACTGCAATATGTTTTTTTGGAAAAAACTCAATCCTCCCCCTCCACTACAATTGATTATGTCGATTAATATTGGCATTAAG

>NC_008149|4|4|2836931-2837052|CRISPRCasFinder
CAATTGATTATATCGATTAATATTGGCATTAAG	AGATTTAATACTGCAATATGTTTTTTTGGAAAAAACTCAATCCTCCCCCTCCACTA
CAATTGATTATGTCGATTAATATTGGCATTAAG

Protein	Signature genes	Signature genes Name	Protein_function
NC_008149.1\|WP_002228570.1\|2829517_2829958_-\|lipocalin-like-domain-containing-protein	unknown	unknown	gnl\|CDD\|372819
NC_008149.1\|WP_002213058.1\|2847429_2848110_+\|DUF2057-family-protein	unknown	unknown	gnl\|CDD\|179619
NC_008149.1\|WP_002213017.1\|2829231_2829480_-\|acyl-carrier-protein	unknown	unknown	gnl\|CDD\|180851
NC_008149.1\|WP_002213028.1\|2832301_2833540_-\|hydroxymethylglutaryl-CoA-synthase-family-protein	unknown	unknown	gnl\|CDD\|225959
NC_008149.1\|WP_002213030.1\|2833555_2834293_-\|SDR-family-oxidoreductase	unknown	unknown	gnl\|CDD\|187594
NC_008149.1\|WP_002213056.1\|2846697_2847114_-\|CoA-binding-protein	unknown	unknown	gnl\|CDD\|224745
NC_008149.1\|WP_002213054.1\|2846271_2846589_+\|heat-shock-protein-HspQ	unknown	unknown	gnl\|CDD\|184526
NC_008149.1\|WP_002213039.1\|2838204_2840622_+\|GNAT-family-N-acetyltransferase	unknown	unknown	gnl\|CDD\|366708
NC_008149.1\|WP_002213025.1\|2830835_2831588_-\|enoyl-CoA-hydratase/isomerase-family-protein	unknown	unknown	gnl\|CDD\|235936
NC_008149.1\|WP_002213046.1\|2844267_2844597_+\|sulfurtransferase-TusE	unknown	unknown	gnl\|CDD\|225472
NC_008149.1\|WP_002213024.1\|2830044_2830833_-\|SDR-family-oxidoreductase	unknown	unknown	gnl\|CDD\|212491
NC_008149.1\|WP_002213026.1\|2831589_2832309_-\|enoyl-CoA-hydratase/isomerase-family-protein	unknown	unknown	gnl\|CDD\|223955
NC_008149.1\|WP_002213034.1\|2835567_2836092_-\|beta-hydroxyacyl-ACP-dehydratase	unknown	unknown	gnl\|CDD\|223835
NC_008149.1\|WP_002213032.1\|2834294_2835578_-\|beta-ketoacyl-[acyl-carrier-protein]-synthase-family-protein	unknown	unknown	gnl\|CDD\|238430
NC_008149.1\|WP_002213060.1\|2848288_2848753_+\|methylglyoxal-synthase	unknown	unknown	gnl\|CDD\|179969
NC_008149.1\|WP_002221095.1\|2848813_2850868_-\|DNA-helicase-IV	unknown	unknown	gnl\|CDD\|182930
NC_008149.1\|WP_002213049.1\|2844648_2844927_-\|acylphosphatase	unknown	unknown	gnl\|CDD\|184675
NC_008149.1\|WP_002213036.1\|2836355_2836574_-\|hypothetical-protein	unknown	unknown	unknown
NC_008149.1\|WP_002213052.1\|2845020_2846211_+\|23S-rRNA-(cytosine(1962)-C(5))-methyltransferase-RlmI	unknown	unknown	gnl\|CDD\|185082
NC_008149.1\|WP_002213038.1\|2837304_2838051_+\|SDR-family-oxidoreductase	unknown	unknown	gnl\|CDD\|180440

Protein	Function_ID	Function_description	E-value
NC_008149.1\|WP_002228570.1\|2829517_2829958_-\|lipocalin-like-domain-containing-protein	gnl\|CDD\|372819	pfam13924, Lipocalin_5, Lipocalin-like domain. This family includes domains distantly related to lipocalins. However, they do contain the important GXW motif in the first strand. The protein in this family include aln5, which is involved in biosynthesis of alnumycin. The family also includes the ZFK protein from Trypanosoma brucei which is a protein kinase. This domain is at the C-terminus of that protein. The domain is also found as the C-terminal domain in StiJ a protein involved in producing stigmatellin. This domain has been assumed to catalyze a final cyclisation reaction.	5.67247e-46
NC_008149.1\|WP_002213054.1\|2846271_2846589_+\|heat-shock-protein-HspQ	gnl\|CDD\|184526	PRK14129, PRK14129, heat shock protein HspQ; Provisional.	3.64231e-72
NC_008149.1\|WP_002213017.1\|2829231_2829480_-\|acyl-carrier-protein	gnl\|CDD\|180851	PRK07117, PRK07117, acyl carrier protein; Validated.	4.77778e-09
NC_008149.1\|WP_002213030.1\|2833555_2834293_-\|SDR-family-oxidoreductase	gnl\|CDD\|187594	cd05333, BKR_SDR_c, beta-Keto acyl carrier protein reductase (BKR), involved in Type II FAS, classical (c) SDRs. This subgroup includes the Escherichai coli K12 BKR, FabG. BKR catalyzes the NADPH-dependent reduction of ACP in the first reductive step of de novo fatty acid synthesis (FAS). FAS consists of four elongation steps, which are repeated to extend the fatty acid chain through the addition of two-carbo units from malonyl acyl-carrier protein (ACP): condensation, reduction, dehydration, and a final reduction. Type II FAS, typical of plants and many bacteria, maintains these activities on discrete polypeptides, while type I FAS utilizes one or two multifunctional polypeptides. BKR resembles enoyl reductase, which catalyzes the second reduction step in FAS. SDRs are a functionally diverse family of oxidoreductases that have a single domain with structurally conserved Rossmann fold (alpha/beta folding pattern with a central beta-sheet) NAD(P)(H) binding region and a structurally diverse C-terminal region. Classical SDRs are typically about 250 residues long, while extended SDRS are approximately 350 residues. Sequence identity between different SDR enzymes are typically in the 15-30% range, but the enzymes share the Rossmann fold NAD binding motif and characteristic NAD-binding and catalytic sequence patterns. These enzymes have a 3-glycine N-terminal NAD(P)(H) binding pattern: TGxxxGxG in classical SDRs. Extended SDRs have additional elements in the C-terminal region, and typically have a TGXXGXXG cofactor binding motif. Complex (multidomain) SDRs such as ketoreductase domains of fatty acid synthase have a GGXGXXG NAD(P) binding motif and an altered active site motif (YXXXN). Fungal type type ketoacyl reductases have a TGXXXGX(1-2)G NAD(P)-binding motif. Some atypical SDRs have lost catalytic activity and/or have an unusual NAD(P) binding motif and missing or unusual active site residues. Reactions catalyzed within the SDR family include isomerization, decarboxylation, epimerization, C=N bond reduction, dehydratase activity, dehalogenation, Enoyl-CoA reduction, and carbonyl-alcohol oxidoreduction. A critical catalytic Tyr residue (Tyr-151, human 15-hydroxyprostaglandin dehydrogenase (15-PGDH) numbering), is often found in a conserved YXXXK pattern. In addition to the Tyr and Lys, there is often an upstream Ser (Ser-138, 15-PGDH numbering) and/or an Asn (Asn-107, 15-PGDH numbering) or additional Ser, contributing to the active site. Substrates for these enzymes include sugars, steroids, alcohols, and aromatic compounds. The standard reaction mechanism is a proton relay involving the conserved Tyr-151 and Lys-155, and well as Asn-111 (or Ser). Some SDR family members, including 17 beta-hydroxysteroid dehydrogenase contain an additional helix-turn-helix motif that is not generally found among SDRs.	2.26541e-68
NC_008149.1\|WP_002213056.1\|2846697_2847114_-\|CoA-binding-protein	gnl\|CDD\|224745	COG1832, COG1832, Predicted CoA-binding protein [General function prediction only].	1.53332e-71
NC_008149.1\|WP_002213058.1\|2847429_2848110_+\|DUF2057-family-protein	gnl\|CDD\|179619	PRK03641, PRK03641, DUF2057 family protein.	4.09411e-122
NC_008149.1\|WP_002213026.1\|2831589_2832309_-\|enoyl-CoA-hydratase/isomerase-family-protein	gnl\|CDD\|223955	COG1024, CaiD, Enoyl-CoA hydratase/carnithine racemase [Lipid metabolism].	1.17502e-35
NC_008149.1\|WP_002213039.1\|2838204_2840622_+\|GNAT-family-N-acetyltransferase	gnl\|CDD\|366708	pfam01565, FAD_binding_4, FAD binding domain. This family consists of various enzymes that use FAD as a co-factor, most of the enzymes are similar to oxygen oxidoreductase. One of the enzymes Vanillyl-alcohol oxidase (VAO) has a solved structure, the alignment includes the FAD binding site, called the PP-loop, between residues 99-110. The FAD molecule is covalently bound in the known structure, however the residue that links to the FAD is not in the alignment. VAO catalyzes the oxidation of a wide variety of substrates, ranging form aromatic amines to 4-alkylphenols. Other members of this family include D-lactate dehydrogenase, this enzyme catalyzes the conversion of D-lactate to pyruvate using FAD as a co-factor; mitomycin radical oxidase, this enzyme oxidizes the reduced form of mitomycins and is involved in mitomycin resistance. This family includes MurB an UDP-N-acetylenolpyruvoylglucosamine reductase enzyme EC:1.1.1.158. This enzyme is involved in the biosynthesis of peptidoglycan.	1.41205e-31
NC_008149.1\|WP_002213025.1\|2830835_2831588_-\|enoyl-CoA-hydratase/isomerase-family-protein	gnl\|CDD\|235936	PRK07110, PRK07110, polyketide biosynthesis enoyl-CoA hydratase; Validated.	2.57932e-133
NC_008149.1\|WP_002213046.1\|2844267_2844597_+\|sulfurtransferase-TusE	gnl\|CDD\|225472	COG2920, DsrC, Dissimilatory sulfite reductase (desulfoviridin), gamma subunit [Inorganic ion transport and metabolism].	2.4785e-71
NC_008149.1\|WP_002213024.1\|2830044_2830833_-\|SDR-family-oxidoreductase	gnl\|CDD\|212491	cd05233, SDR_c, classical (c) SDRs. SDRs are a functionally diverse family of oxidoreductases that have a single domain with a structurally conserved Rossmann fold (alpha/beta folding pattern with a central beta-sheet), an NAD(P)(H)-binding region, and a structurally diverse C-terminal region. Classical SDRs are typically about 250 residues long, while extended SDRs are approximately 350 residues. Sequence identity between different SDR enzymes are typically in the 15-30% range, but the enzymes share the Rossmann fold NAD-binding motif and characteristic NAD-binding and catalytic sequence patterns. These enzymes catalyze a wide range of activities including the metabolism of steroids, cofactors, carbohydrates, lipids, aromatic compounds, and amino acids, and act in redox sensing. Classical SDRs have an TGXXX[AG]XG cofactor binding motif and a YXXXK active site motif, with the Tyr residue of the active site motif serving as a critical catalytic residue (Tyr-151, human prostaglandin dehydrogenase (PGDH) numbering). In addition to the Tyr and Lys, there is often an upstream Ser (Ser-138, PGDH numbering) and/or an Asn (Asn-107, PGDH numbering) contributing to the active site; while substrate binding is in the C-terminal region, which determines specificity. The standard reaction mechanism is a 4-pro-S hydride transfer and proton relay involving the conserved Tyr and Lys, a water molecule stabilized by Asn, and nicotinamide. Extended SDRs have additional elements in the C-terminal region, and typically have a TGXXGXXG cofactor binding motif. Complex (multidomain) SDRs such as ketoreductase domains of fatty acid synthase have a GGXGXXG NAD(P)-binding motif and an altered active site motif (YXXXN). Fungal type ketoacyl reductases have a TGXXXGX(1-2)G NAD(P)-binding motif. Some atypical SDRs have lost catalytic activity and/or have an unusual NAD(P)-binding motif and missing or unusual active site residues. Reactions catalyzed within the SDR family include isomerization, decarboxylation, epimerization, C=N bond reduction, dehydratase activity, dehalogenation, Enoyl-CoA reduction, and carbonyl-alcohol oxidoreduction.	5.49415e-40
NC_008149.1\|WP_002213028.1\|2832301_2833540_-\|hydroxymethylglutaryl-CoA-synthase-family-protein	gnl\|CDD\|225959	COG3425, PksG, 3-hydroxy-3-methylglutaryl CoA synthase [Lipid metabolism].	1.57028e-141
NC_008149.1\|WP_002213034.1\|2835567_2836092_-\|beta-hydroxyacyl-ACP-dehydratase	gnl\|CDD\|223835	COG0764, FabA, 3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) dehydratases [Lipid metabolism].	1.09929e-42
NC_008149.1\|WP_002213032.1\|2834294_2835578_-\|beta-ketoacyl-[acyl-carrier-protein]-synthase-family-protein	gnl\|CDD\|238430	cd00834, KAS_I_II, Beta-ketoacyl-acyl carrier protein (ACP) synthase (KAS), type I and II. KASs are responsible for the elongation steps in fatty acid biosynthesis. KASIII catalyses the initial condensation and KAS I and II catalyze further elongation steps by Claisen condensation of malonyl-acyl carrier protein (ACP) with acyl-ACP.	2.93328e-136
NC_008149.1\|WP_002213060.1\|2848288_2848753_+\|methylglyoxal-synthase	gnl\|CDD\|179969	PRK05234, mgsA, methylglyoxal synthase; Validated.	2.55286e-93
NC_008149.1\|WP_002221095.1\|2848813_2850868_-\|DNA-helicase-IV	gnl\|CDD\|182930	PRK11054, helD, DNA helicase IV; Provisional.	0
NC_008149.1\|WP_002213049.1\|2844648_2844927_-\|acylphosphatase	gnl\|CDD\|184675	PRK14426, PRK14426, acylphosphatase; Provisional.	1.02172e-54
NC_008149.1\|WP_002213052.1\|2845020_2846211_+\|23S-rRNA-(cytosine(1962)-C(5))-methyltransferase-RlmI	gnl\|CDD\|185082	PRK15128, PRK15128, 23S rRNA (cytosine(1962)-C(5))-methyltransferase RlmI.	0
NC_008149.1\|WP_002213038.1\|2837304_2838051_+\|SDR-family-oxidoreductase	gnl\|CDD\|180440	PRK06172, PRK06172, SDR family oxidoreductase.	1.01866e-70

>NC_008149.1|WP_002213036.1|2836355_2836574_-|hypothetical-protein
MYLLQQIELCPDQILHAWKISQNPQVSEVFEIEVVSSEEDAEEAVLFWKAYFSSLGETVIDGRHVGDTFSRF
>NC_008149.1|WP_002213034.1|2835567_2836092_-|beta-hydroxyacyl-ACP-dehydratase
MKNTELNFLKTNFLFNQDITNELNTSFGQDIIKKMIPHREPFLMVDNVELINIECRLIKAIRRVDEKDPVFGGHFPNDPIYPGVLQQESMFQTALILMYFLLNETAIPPAEENIIHAVGTRVYDVFHLSAVRPGELMTIRCCITEYDTFLATAIVQITVNDQIVTVGKGEFHVF
>NC_008149.1|WP_002213032.1|2834294_2835578_-|beta-ketoacyl-[acyl-carrier-protein]-synthase-family-protein
MSSDRIVITGVAINTPIGDTLDLVGNNLLSGKSAIGYWRNFDTSNIYSKIGGQIPEYDIEGKLHAFSNRIPDIVLSRAEKVFKQTTKGVQLSVLMAMEAWLDAGLFEHIIDPFDCGIICGGHNLSDKYLLDQQKIFSDEPEFIDAFSGLNSLDTDHSSSVAQVLNTKGFAYLVGGTCATGNIAIQTAINAIKVDKKQVVAVVCPMASFHPMMLHSLTILEAICYSQYQDTPTKASRPYDINRSGFLPSEGGAVLIFEQAEHAKNRGAKIYAELLGASVNSDANHLGDPSHEGQVRVIQDVLKKCNISPEQVDYVSAHATSTKLGDIVELKSIKRVFGSHAEKLIINAPKSLLGHTMWASGVVEAAIAIWQMRQGEFHQSHNIETLDPAVELNVCASGNVKKEVNIFLNNSFGMGGINSASLFSRYHG
>NC_008149.1|WP_002213030.1|2833555_2834293_-|SDR-family-oxidoreductase
MNLFISGGASGIGRSVVIAALSKGWNVGFSYHNNKEGAQQLLDIAVAEFPRQLCRAYQLDVIDSGAVEYVGDRLLVDFSNIDAVVCNAGIDLPGNLVSMTDEDWALVLNTNLTGTFYLIRYFLPLFLANKYGRIVTLSSLAKDGSSGQAAYAASKAGLVGLTKTTAKEYGHFGITANVVVPGLINTEIIGDDIKGIKNFFAQYAPVGRLGSPSEVAEAILFLVAKESSYVNGAVFNVTGGIDWVY
>NC_008149.1|WP_002213028.1|2832301_2833540_-|hydroxymethylglutaryl-CoA-synthase-family-protein
MNSIGIEKISIYPSSLALKLSELAQARGGDNKYIQESLMVIKRSLVPQWEDAVTLAVNSAKDMLNDQDRSDIGLFIIATESGLDQEKAISTWAHRYLGLPATCRVFELKSACHAGAAALKMAESWISSGLNRGKKVLLINVDISNNMICHGKMEYSLGAGAIALLISDNPVFAVIETGKSGIHTHEVTDVIRPLPWKEVAFDVEASLFSYMDGLENAFEEYCHQTPEARESTYFNYNLYHVPFPGISKEAHKVLLELQGLFGKEALATSFKQKVMPSLYYAQKIGATYCGSIFLSLFSLMVKAPEIKSGDRIGVYSYGSGSCAEYFSMQVGDQAVEIAQQQGAALDILLTQRKILDVAAYEQLENARSAQMQGKDYRLDGDNLQDWYTHHYSGSGLLILERIDNHLRRYRYA
>NC_008149.1|WP_002213026.1|2831589_2832309_-|enoyl-CoA-hydratase/isomerase-family-protein
MHEYVTVPIKFSPDSLADFENRFISALNDERYKVIVLIGGPTYFSMGMDLTYISTHYDADFVSQFCHILKMVRNSHKPVLAKVEGNVIAGGLALLSVVDFILSSDSASFSLPEVTFGITPTIAMSCLLERIRPHHLKYFVWSSSVISAKQALKWGLIDQINTLENLDQDIQVISNKLSRIPKSAIRESKLLLAEQYSFEESLDLGSHLLVERLNDAQTIEKIRHYLEDIKLFNDEYADD
>NC_008149.1|WP_002213025.1|2830835_2831588_-|enoyl-CoA-hydratase/isomerase-family-protein
MKKIYLRKSDEGIAFMHINDPVNKNAIDDEFCLQLHGIVDTIKQDKTIKVLILVGLPDIFCTGGTEAFLQSLITHYKTNIEHEYANHLKHFLNIPIPVIAAMEGSATGGGLVLGLYADILVAAEESRYGMSFMNMGFTPGMGSTAMSKEAFGYYTGFEMMVTGNYIRGSELKGKCCFNYILPRAMVMEKAIELATSIAEKPRHSLELLKKYMSIDRRKMLEETSTIEAFMHHIAFNQSNIEQQIQDNYTG
>NC_008149.1|WP_002213024.1|2830044_2830833_-|SDR-family-oxidoreductase
MLNNLSEMTVLVTGGTKGIGRATVESFVKAGAKVYGTYFWGDNLDELENHFSQYLNRPVFLQADISDEEITTQLIEKIAQENKKIDILILNAAFAPQFKDTYKFRGLLDSIEHNSWPLITYIDCIKQHFGQYPGYVVAITSEGHRSCHITGYDYVAASKAVLETLTKYIGARENIIINCISPGVVDTEAFELVFGKKAQAFIRKFDPDFIVSPEAVGNVSVALCSGLMDAVRGQVITVDNGRMFTDNFTKWIDMIETNFIEK
>NC_008149.1|WP_002228570.1|2829517_2829958_-|lipocalin-like-domain-containing-protein
MSNPNRNLFLGRWKLESCIGNSGGIHIYPIGREPFGMLIYTEQYMMVFISSVERTQFSTEDIRAIPSEQIVADFPKFETYCGHYIVNHDEKIVTHFIDNSKIPNQIGTQFRRYFSFEHEKLVLKSIDSLLLNDESWLFELVWNKQE
>NC_008149.1|WP_002213017.1|2829231_2829480_-|acyl-carrier-protein
MDRDHIASIVKKHIVNSIDGAKEHEIDLQKSMADYGASSLDIVSVVSGVMRELKIKIPRTELKNIKSINGLIDLFVTSSSES
>NC_008149.1|WP_002213038.1|2837304_2838051_+|SDR-family-oxidoreductase
MKKTILITGALSGIGNTATKLFSEMGYNVVFSGRRPEEGRVILDDLKRINKDVLYVNADMNSESDIKHLIEMTLERFGSLDVAVNCAGTVGETAEIQAVTQDNFHLVFNTNVLGTLLAMKYQIPVMVERGKGSIINISSIAGLVGLPSTGIYVASKHAIEGLTKTAALEVATTGVRINSISPGPVEGKMFDRFLGHDENNKKAFIEMMPNKRFTTQEEVAHTIVFLAEDNVTAITGQTITIDGGYTAQ
>NC_008149.1|WP_002213039.1|2838204_2840622_+|GNAT-family-N-acetyltransferase
MTTTLDIINSAKDLDPAEYRAFFLQSKAPLFYDLRFLIAAEQSPLLNVSKIFYLLARDEGRLIALVPLYLQEFRSADPLGLLISSAKLSIESEERGLFSHIIHCTDTTIPTLSHDPSLYARIFDAITAIAQAELARYFCFLNVQDGVLLREAQRNGLNINYMVDKFSIELDAFPDFDSFAQALPKYRRYEMVRQLRIFNRSDAKVRILAPPFDNEIEKLARLYYLTTQRLGTPYYWPESQLAVFCRLCGDLVRLIVVEQNGQIVSGFICFEEDGALHFWSAGMDDESSDFSPYTLGVSAVYRYAFEKGINLIECGRLNSHIKTRLGFKPKRLYSIVSQDLGIPAATQTSLSQLKLASQLDGEVRLASHPAFDEWYLTSVWNGRGPTRRPAGIVRAATEADVIRTIVFAKERGMEVSVRGSGHNYVGCFLRVDTLMLDISGLKGLDIDSRHKRAIVESGVSSGQLCHALAAKGLAFPTGHVKEVGISGFLLGGGLGINCSQWGGMSVFNVQALDIVTADGHLRHVSETQEPDLFWAARGAGPCSFFVVTRFYLSCYSLPRVITNSLYTLPFTYLHDLLARLEDASPPTNLQVMVSVSPPTSGDTPAVLLNILAFTDSPQEAQALCESFETRLELPLTALAINQPSNFETIYEQFSSMVVSKRFYADNILTDNTQELVSILSRYLSDAPSRGALTTIFWRGVTTYPQAAFSAHGKFFVSTYAQWDDAKDDSVNKYWLKRMYDELQEIARSRYINEYDLETRAGETSKCFAAENWERLQRLRLEYDPDGVFVDVQQLEEHGDQPGANN
>NC_008149.1|WP_002213046.1|2844267_2844597_+|sulfurtransferase-TusE
MLEFEGRIIDTDAQGYLKNSTDWSEALAPVLAEQEGITLTEPHWEVVRFVRAFYQEFNTSPAIRMLVKAMAQKYGEEKGNSRYLYRLFPKGPAKQATKIAGLPKPVKCI
>NC_008149.1|WP_002213049.1|2844648_2844927_-|acylphosphatase
MSKIYIVAYVYGVVQGVGFRYSTQRQAQQLGVTGYAKNCDDGSVEVVASGNPQAVERLMEWIRQGGPRGARVDRLLTEPYPPTPFETFSIRY
>NC_008149.1|WP_002213052.1|2845020_2846211_+|23S-rRNA-(cytosine(1962)-C(5))-methyltransferase-RlmI
MTVRLILAKGREKSLLRRHPWIFSGAVQRLEGDALSGETIDILDSQGKWLARAAYSPESQILARVWTFQQDEVIDCAFFIRRLQQAQNWRDWLAQRDGLNGYRLIAGESDGLPGITIDRFQNFLVLQLLSAGAEYQRETLVSALQHCYPECSIYDRSDVSVRKKEGLPLTQGLICGEMPPALLPISENGMQLFVDIQQGHKTGFYLDQRDSRLAARNYANGRRVLNCFSYTGAFAVAALMGNCQQVISVDTSQSVLDIAKQNIELNQLDLSKTEFVRDDVFQLLRSYRAQGEKFDLIIMDPPKFVENKSQLASACRGYKDINMLAIQLLRPGGILLSFSCSGLMPVDLFQKILADAALDAGHDIQFIEQFRQAADHPVIAAYPEGLYLKGFACRVM
>NC_008149.1|WP_002213054.1|2846271_2846589_+|heat-shock-protein-HspQ
MIASKFGIGQQVRHSLHGYLGVVIDIDPEYSLAPPEPDEVANNKTLRSSPWYHVVIEDDDGQPVHTYLAEAQLTYEDVDAHPEQPSLDELAASIRHQLQAPHLRN
>NC_008149.1|WP_002213056.1|2846697_2847114_-|CoA-binding-protein
MHDKDIADILKKVKTIALVGASDIPSRPSYRVMAYLLQQGYQVTPVNPKLAGELLLGQLVYAELADIPHAIDMVDVFRNSDAAYCIAQDAIAIGAKVLWLQIGVINEQAAILATDAGLQVVMDRCPKIELPRLGLEKG
>NC_008149.1|WP_002213058.1|2847429_2848110_+|DUF2057-family-protein
MKLGLVAGMLAVCFSFSSVAMTLKLTPEIDLLVVDGKNMSGSLLKGADSLELNSGMHQILFKVIKPLPTDPLVLYSSPPLIVVFNAHNTRSVAIKLPVINTLRDGHQFSKNPLYQLIGDNGHPLSVRHDVLRQDHLNNSTTLETVMAAYNVGKYNASVPAFAAIPPSPVSAVPGTTIPVAGVNTPHKTASLQGENVTEQMLQYWFLQANPETQKRFLIWAKKQPIH
>NC_008149.1|WP_002213060.1|2848288_2848753_+|methylglyoxal-synthase
MELTTRTIAARKHIALVSHDHCKKSLLAWVMENRDLLAQHELYATGTTGNLVQKATGIDVHCLLSGPMGGDQEVGALISEKKIDILIFFWDPLNAVPHDPDVKALLRLATVWNIPVATNRSTADFLIGSTLFSSEVTIAIPDYDRYMQQRLDLK
>NC_008149.1|WP_002221095.1|2848813_2850868_-|DNA-helicase-IV
MELKATSFGKHLSQHPYNRVRLLNAGIEVCGDKHQYLIPFNQLVSIQCKRGIVWGELEFELPQQKVVRLHGTEWQETQHFYHYLLGVWQQWSEEMSQVCAEVLHKQVESIKRIEQQDKWFKRSELGQIQVMIREAFSALPMPVERLAAFESCRADYECCLRWLQQGRHSVERCNQQWTARMLEEYQDFFQNVETSPLNASQSRAVVNGEDSVLVLAGAGSGKTSVLVARAGWLLRRNEALPEQILLLAFGRQAADEMNSRIKQRLGVDSIQAKTFHALALHIIQQGSRKTPVISKLESDSQARRALLIQHWQQQCSEKKAQAKGWREWLTDELEWDVADGDFWQDKRLAARLASRLERWVGLMRMYGGSQAEMIEQANDEVRDLFQKRIRLMAPLLKAWKTALKDEGAVDFSGLIHQAVNLLEKGRFVSPWKHVLVDEFQDISPQRAMLLAALRKQNKQTCLFAVGDDWQAIYRFSGAELSLTTAFSEHFGEGAECALDTTYRFNDRIGDIANRFIQQNPYQLKKPLNSLSKGNKKSVMILPDEQLEALLDKLSGFVKDGERILILARYHHLRPEVLQKAATRWPKLTIDFMTIHASKGQQADYVIIVGLHEGNDGFPAAARESVLEDVLLPPPEDFPDAEERRLLYVAITRAKHQVWLLQDTARPSIFVSQLSELGALVQRKP

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity
NC_008149_2	2.4\|1221574\|32\|NC_008149\|CRISPRCasFinder,CRT	1221574-1221605	32	NC_008149.1	1788909-1788940	0	1.0

1. spacer 2.4|1221574|32|NC_008149|CRISPRCasFinder,CRT matches to position: 1788909-1788940, mismatch: 0, identity: 1.0

agactgatgcaagatggcggtatgcgtacaga	CRISPR spacer
agactgatgcaagatggcggtatgcgtacaga	Protospacer
********************************

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NC_008149_2	2.4\|1221574\|32\|NC_008149\|CRISPRCasFinder,CRT	1221574-1221605	32	MT374852	Yersinia phage vB_YpM_3, complete genome	12-43	0	1.0
NC_008149_3	3.4\|2711162\|28\|NC_008149\|PILER-CR	2711162-2711189	28	MH616963	CrAssphage sp. isolate ctbg_1, complete genome	86944-86971	5	0.821
NC_008149_3	3.4\|2711162\|28\|NC_008149\|PILER-CR	2711162-2711189	28	MT774386	CrAssphage cr110_1, complete genome	42860-42887	5	0.821
NC_008149_3	3.4\|2711162\|28\|NC_008149\|PILER-CR	2711162-2711189	28	NZ_CP028934	Campylobacter jejuni strain FORC_083 plasmid pFORC_083_2, complete sequence	25851-25878	6	0.786
NC_008149_3	3.2\|2711158\|32\|NC_008149\|CRISPRCasFinder,CRT	2711158-2711189	32	MH616963	CrAssphage sp. isolate ctbg_1, complete genome	86942-86973	7	0.781
NC_008149_3	3.4\|2711162\|28\|NC_008149\|PILER-CR	2711162-2711189	28	MK415408	CrAssphage GF1-2_000079F, complete genome	71106-71133	7	0.75
NC_008149_3	3.2\|2711158\|32\|NC_008149\|CRISPRCasFinder,CRT	2711158-2711189	32	NZ_CP010358	Acinetobacter johnsonii XBB1 plasmid pXBB1-8, complete sequence	46720-46751	8	0.75
NC_008149_3	3.2\|2711158\|32\|NC_008149\|CRISPRCasFinder,CRT	2711158-2711189	32	NC_019694	Oscillatoria acuminata PCC 6304 plasmid pOSCIL6304.02, complete sequence	20911-20942	8	0.75
NC_008149_2	2.3\|1221513\|33\|NC_008149\|PILER-CR,CRISPRCasFinder,CRT	1221513-1221545	33	NZ_CP040366	Bacillus flexus isolate 1-2-1 plasmid punnamed3, complete sequence	923-955	9	0.727
NC_008149_3	3.2\|2711158\|32\|NC_008149\|CRISPRCasFinder,CRT	2711158-2711189	32	MT774386	CrAssphage cr110_1, complete genome	42858-42889	9	0.719
NC_008149_3	3.2\|2711158\|32\|NC_008149\|CRISPRCasFinder,CRT	2711158-2711189	32	NZ_CP028934	Campylobacter jejuni strain FORC_083 plasmid pFORC_083_2, complete sequence	25849-25880	9	0.719

1. spacer 2.4|1221574|32|NC_008149|CRISPRCasFinder,CRT matches to MT374852 (Yersinia phage vB_YpM_3, complete genome) position: , mismatch: 0, identity: 1.0

agactgatgcaagatggcggtatgcgtacaga	CRISPR spacer
agactgatgcaagatggcggtatgcgtacaga	Protospacer
********************************

2. spacer 3.4|2711162|28|NC_008149|PILER-CR matches to MH616963 (CrAssphage sp. isolate ctbg_1, complete genome) position: , mismatch: 5, identity: 0.821

aagttctttttgtcagcatctttaataa	CRISPR spacer
ataatctttttatcagcatcttttataa	Protospacer
* . *******.*********** ****

3. spacer 3.4|2711162|28|NC_008149|PILER-CR matches to MT774386 (CrAssphage cr110_1, complete genome) position: , mismatch: 5, identity: 0.821

aagttctttttgtcagcatctttaataa	CRISPR spacer
agtttctttttatcagcatcttcaatag	Protospacer
*. ********.**********.****.

4. spacer 3.4|2711162|28|NC_008149|PILER-CR matches to NZ_CP028934 (Campylobacter jejuni strain FORC_083 plasmid pFORC_083_2, complete sequence) position: , mismatch: 6, identity: 0.786

aagttctttttgtcagcatctttaataa	CRISPR spacer
actttctttttgtcagcgtctgtaatgt	Protospacer
*  **************.*** ****.

5. spacer 3.2|2711158|32|NC_008149|CRISPRCasFinder,CRT matches to MH616963 (CrAssphage sp. isolate ctbg_1, complete genome) position: , mismatch: 7, identity: 0.781

ttaagttctttttgtcagcatctttaataaat	CRISPR spacer
taataatctttttatcagcatcttttataatt	Protospacer
* * . *******.*********** **** *

6. spacer 3.4|2711162|28|NC_008149|PILER-CR matches to MK415408 (CrAssphage GF1-2_000079F, complete genome) position: , mismatch: 7, identity: 0.75

aagttctttttgtcagcatctttaataa	CRISPR spacer
ataagacttttatcagcatctttaataa	Protospacer
* .   .****.****************

7. spacer 3.2|2711158|32|NC_008149|CRISPRCasFinder,CRT matches to NZ_CP010358 (Acinetobacter johnsonii XBB1 plasmid pXBB1-8, complete sequence) position: , mismatch: 8, identity: 0.75

ttaagttctttttgtcagcatctttaataaat	CRISPR spacer
gtgccatattttcgtcagcatcattaataaat	Protospacer
 *.   * ****.********* *********

8. spacer 3.2|2711158|32|NC_008149|CRISPRCasFinder,CRT matches to NC_019694 (Oscillatoria acuminata PCC 6304 plasmid pOSCIL6304.02, complete sequence) position: , mismatch: 8, identity: 0.75

ttaagttctttttgtcagcatctttaataaat	CRISPR spacer
ttgatgctcttttggcagcttctttaataaat	Protospacer
**.*  ...***** **** ************

9. spacer 2.3|1221513|33|NC_008149|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP040366 (Bacillus flexus isolate 1-2-1 plasmid punnamed3, complete sequence) position: , mismatch: 9, identity: 0.727

ccgaaatcatcagatgtaattaagatttttgct	CRISPR spacer
aatggattatcagatgtaattaagtttttttcc	Protospacer
   ..**.**************** ***** *.

10. spacer 3.2|2711158|32|NC_008149|CRISPRCasFinder,CRT matches to MT774386 (CrAssphage cr110_1, complete genome) position: , mismatch: 9, identity: 0.719

ttaagttctttttgtcagcatctttaataaat	CRISPR spacer
caagtttctttttatcagcatcttcaatagca	Protospacer
. *. ********.**********.****.

11. spacer 3.2|2711158|32|NC_008149|CRISPRCasFinder,CRT matches to NZ_CP028934 (Campylobacter jejuni strain FORC_083 plasmid pFORC_083_2, complete sequence) position: , mismatch: 9, identity: 0.719

ttaagttctttttgtcagcatctttaataaat	CRISPR spacer
taactttctttttgtcagcgtctgtaatgtgc	Protospacer
* *  **************.*** ****. ..

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

235039 : 307572

Escherichia_phage(30.77%)

transposase

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000255944.1\|235039_236062_+\|transposase	IS21-like element IS100 family transposase	A0A2L1IVA1	Escherichia_phage	1.9e-201	100.0
WP_001297096.1\|236061_236841_+	AAA family ATPase	A0A2L1IVB6	Escherichia_phage	4.5e-139	99.6
WP_002211540.1\|236879_237215_+	TatD family hydrolase	NA	NA	NA	NA
WP_002211541.1\|237229_238252_+	porphobilinogen synthase	NA	NA	NA	NA
WP_002211542.1\|238361_238850_-	transcription/translation regulatory transformer protein RfaH	NA	NA	NA	NA
WP_002215917.1\|239097_240594_+	4-hydroxy-3-polyprenylbenzoate decarboxylase	NA	NA	NA	NA
WP_002215918.1\|240648_241350_+	NAD(P)H-flavin reductase	NA	NA	NA	NA
WP_002211545.1\|241509_242673_-	acetyl-CoA C-acyltransferase FadA	NA	NA	NA	NA
WP_002211546.1\|242684_244874_-	fatty acid oxidation complex subunit alpha FadB	NA	NA	NA	NA
WP_002211547.1\|245200_246532_+	Xaa-Pro dipeptidase	NA	NA	NA	NA
WP_002211548.1\|246531_246741_+	YigZ family protein	NA	NA	NA	NA
WP_002213759.1\|246845_247304_+\|transposase	IS200/IS605-like element IS1541A family transposase	NA	NA	NA	NA
WP_002211550.1\|247892_249344_+	Trk system potassium transporter TrkH	NA	NA	NA	NA
WP_002215920.1\|249365_249899_+	menaquinone-dependent protoporphyrinogen IX dehydrogenase	NA	NA	NA	NA
WP_002212288.1\|256036_257074_+	UDP-N-acetylmuramate dehydrogenase	NA	NA	NA	NA
WP_002212289.1\|257070_258030_+	bifunctional biotin--[acetyl-CoA-carboxylase] ligase/biotin operon repressor BirA	NA	NA	NA	NA
WP_002212290.1\|258064_259015_-	type I pantothenate kinase	A0A1B1ISL9	uncultured_Mediterranean_phage	8.7e-28	31.2
WP_002355327.1\|259225_259684_-	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_000255944.1\|259866_260889_+\|transposase	IS21-like element IS100 family transposase	A0A2L1IVA1	Escherichia_phage	1.9e-201	100.0
WP_001297096.1\|260888_261668_+	AAA family ATPase	A0A2L1IVB6	Escherichia_phage	4.5e-139	99.6
WP_002210670.1\|264160_264544_+	preprotein translocase subunit SecE	NA	NA	NA	NA
WP_002210671.1\|264545_265091_+	transcription termination/antitermination protein NusG	A0A291AUS6	Sinorhizobium_phage	5.9e-13	28.3
WP_002210672.1\|265281_265710_+	50S ribosomal protein L11	NA	NA	NA	NA
WP_002210673.1\|265713_266418_+	50S ribosomal protein L1	NA	NA	NA	NA
WP_002210674.1\|266782_267280_+	50S ribosomal protein L10	NA	NA	NA	NA
WP_002210675.1\|267346_267715_+	50S ribosomal protein L7/L12	NA	NA	NA	NA
WP_002210676.1\|268057_272086_+	DNA-directed RNA polymerase subunit beta	A0A0N9R0J7	Chrysochromulina_ericina_virus	1.2e-22	29.0
WP_002210677.1\|272214_276435_+	DNA-directed RNA polymerase subunit beta'	A0A2I7QNZ7	Vibrio_phage	8.5e-67	27.0
WP_002213775.1\|276561_277020_-\|transposase	IS200/IS605-like element IS1541B family transposase	NA	NA	NA	NA
WP_002210678.1\|277451_278582_-	2-iminoacetate synthase ThiH	NA	NA	NA	NA
WP_002228257.1\|278574_279390_-	thiazole synthase	NA	NA	NA	NA
WP_002217275.1\|279391_279607_-	sulfur carrier protein ThiS	NA	NA	NA	NA
WP_002210680.1\|279603_280401_-	HesA/MoeB/ThiF family protein	A0A1V0SAV8	Catovirus	1.6e-11	27.8
WP_002210681.1\|280390_281065_-	thiamine phosphate synthase	NA	NA	NA	NA
WP_002210682.1\|281051_283097_-	phosphomethylpyrimidine synthase ThiC	NA	NA	NA	NA
WP_002210683.1\|283472_283982_-	sigma D regulator	NA	NA	NA	NA
WP_002210684.1\|284078_284861_+	NAD(+) diphosphatase	NA	NA	NA	NA
WP_002210685.1\|284953_285739_+	hypothetical protein	NA	NA	NA	NA
WP_002210686.1\|285857_286925_+	uroporphyrinogen decarboxylase	NA	NA	NA	NA
WP_002210687.1\|286954_287695_+	deoxyribonuclease V	NA	NA	NA	NA
WP_002210688.1\|287740_288331_+	YjaG family protein	NA	NA	NA	NA
WP_002210689.1\|288519_288795_+	DNA-binding protein HU-alpha	A7KV42	Bacillus_phage	3.6e-19	55.6
WP_002355296.1\|288844_289498_+	DUF1481 domain-containing protein	NA	NA	NA	NA
WP_002210691.1\|289645_290932_-	phosphoribosylamine--glycine ligase	NA	NA	NA	NA
WP_002210692.1\|290991_292581_-	bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase	Q58MG4	Prochlorococcus_phage	2.2e-68	49.4
WP_002220999.1\|298880_300089_+\|transposase	IS256 family transposase	A0A218MNI5	uncultured_virus	5.4e-51	50.8
WP_002217538.1\|300146_300677_-	molybdopterin-guanine dinucleotide biosynthesis protein B	NA	NA	NA	NA
WP_002213171.1\|300676_301264_-	molybdenum cofactor guanylyltransferase MobA	NA	NA	NA	NA
WP_002213170.1\|301417_301687_+	YihD family protein	NA	NA	NA	NA
WP_002213169.1\|301777_302764_+	serine/threonine protein kinase	NA	NA	NA	NA
WP_002213168.1\|302791_303415_+	thiol:disulfide interchange protein DsbA	NA	NA	NA	NA
WP_002213164.1\|303906_306705_+	DNA polymerase I	A0A218MKQ4	uncultured_virus	2.7e-69	32.8
WP_002213775.1\|307113_307572_+\|transposase	IS200/IS605-like element IS1541B family transposase	NA	NA	NA	NA

DBSCAN-SWA_2

423937 : 470409

Bodo_saltans_virus(20.0%)

plate,tRNA,transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_002210509.1\|423937_426754_+\|tRNA	isoleucine--tRNA ligase	A0A2H4UVG0	Bodo_saltans_virus	1.0e-63	26.1
WP_002210508.1\|426753_427263_+	signal peptidase II	NA	NA	NA	NA
WP_002228112.1\|427330_427789_+	FKBP-type peptidyl-prolyl cis-trans isomerase	NA	NA	NA	NA
WP_002210506.1\|427769_428723_+	4-hydroxy-3-methylbut-2-enyl diphosphate reductase	NA	NA	NA	NA
WP_002213775.1\|429104_429563_+\|transposase	IS200/IS605-like element IS1541B family transposase	NA	NA	NA	NA
WP_002210504.1\|430015_430837_+	4-hydroxy-tetrahydrodipicolinate reductase	NA	NA	NA	NA
WP_002224759.1\|431309_432485_+	glutamine-hydrolyzing carbamoyl-phosphate synthase small subunit	R4TGJ8	Halovirus	6.9e-51	34.3
WP_002210502.1\|432500_435734_+	carbamoyl-phosphate synthase large subunit	NA	NA	NA	NA
WP_002210501.1\|435961_436576_-	LysE family translocator	NA	NA	NA	NA
WP_002210499.1\|436899_437700_+	threonine/serine exporter ThrE family protein	NA	NA	NA	NA
WP_002210498.1\|437696_438152_+	threonine/serine exporter	NA	NA	NA	NA
WP_002210497.1\|438301_438784_+	type 3 dihydrofolate reductase	A0A219UQN5	Bacillus_phage	4.7e-30	42.6
WP_002213775.1\|438995_439454_+\|transposase	IS200/IS605-like element IS1541B family transposase	NA	NA	NA	NA
WP_071525509.1\|439895_440210_+	DUF3757 domain-containing protein	NA	NA	NA	NA
WP_002210493.1\|440336_440801_+	DUF3757 domain-containing protein	NA	NA	NA	NA
WP_002210492.1\|440890_441760_-	bis(5'-nucleosyl)-tetraphosphatase (symmetrical) ApaH	NA	NA	NA	NA
WP_002210491.1\|441776_442154_-	Co2+/Mg2+ efflux protein ApaG	NA	NA	NA	NA
WP_002210490.1\|442167_442986_-	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))- dimethyltransferase RsmA	NA	NA	NA	NA
WP_002210489.1\|442978_443974_-	4-hydroxythreonine-4-phosphate dehydrogenase PdxA	NA	NA	NA	NA
WP_002210488.1\|443957_445262_-	peptidylprolyl isomerase SurA	NA	NA	NA	NA
WP_002228111.1\|445329_447672_-	LPS assembly protein LptD	NA	NA	NA	NA
WP_002210486.1\|447856_448690_+	co-chaperone DjlA	NA	NA	NA	NA
WP_002210485.1\|448987_449608_-\|tRNA	bifunctional tRNA pseudouridine(32) synthase/23S rRNA pseudouridine(746) synthase RluA	NA	NA	NA	NA
WP_002214747.1\|450830_451574_-	DUF2285 domain-containing protein	NA	NA	NA	NA
WP_002210482.1\|451903_452917_+	ImpA family type VI secretion system protein	NA	NA	NA	NA
WP_002210481.1\|452927_453488_+	type VI secretion system contractile sheath small subunit	NA	NA	NA	NA
WP_002210480.1\|453496_454999_+	type VI secretion system contractile sheath large subunit	NA	NA	NA	NA
WP_002210479.1\|455161_455680_+	type VI secretion system tube protein Hcp	NA	NA	NA	NA
WP_002210478.1\|455753_456197_+\|plate	type VI secretion system baseplate subunit TssE	NA	NA	NA	NA
WP_002210477.1\|456229_458074_+\|plate	type VI secretion system baseplate subunit TssF	NA	NA	NA	NA
WP_002210476.1\|458066_459050_+\|plate	type VI secretion system baseplate subunit TssG	NA	NA	NA	NA
WP_002210475.1\|459067_461656_+	type VI secretion system ATPase TssH	A0A248SJW6	Salicola_phage	1.9e-77	28.7
WP_002210474.1\|461759_464108_+	type VI secretion system tip protein VgrG	A0A2H4JCD4	uncultured_Caudovirales_phage	2.1e-14	32.9
WP_002224087.1\|464120_466340_+	pentapeptide repeat-containing protein	NA	NA	NA	NA
WP_002214739.1\|466365_467469_+	pentapeptide repeat-containing protein	NA	NA	NA	NA
WP_002210473.1\|467461_468079_+	DUF3540 domain-containing protein	NA	NA	NA	NA
WP_002214737.1\|468084_468450_+	DUF4150 domain-containing protein	NA	NA	NA	NA
WP_002210471.1\|468442_468934_+	type VI secretion system lipoprotein TssJ	NA	NA	NA	NA
WP_002210470.1\|469053_470409_+\|plate	type VI secretion system baseplate subunit TssK	NA	NA	NA	NA

DBSCAN-SWA_3

763475 : 833157

Escherichia_phage(13.33%)

integrase,tRNA,transposase,protease

attL 763450:763509|attR 770564:771156

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
763450:763509	attL	NA	NA	NA	NA
WP_002213759.1\|763475_763934_+\|transposase	IS200/IS605-like element IS1541A family transposase	NA	NA	NA	NA
WP_002209313.1\|764201_765461_+\|integrase	integrase arm-type DNA-binding domain-containing protein	B7SYF8	Stenotrophomonas_phage	4.8e-82	42.7
WP_002209314.1\|765614_767525_+	DUF262 domain-containing protein	NA	NA	NA	NA
WP_002209315.1\|767517_768627_+	ATP-binding protein	A0A2H4J2R8	uncultured_Caudovirales_phage	1.5e-143	67.9
WP_001297096.1\|768677_769457_-	AAA family ATPase	A0A2L1IVB6	Escherichia_phage	4.5e-139	99.6
WP_000255944.1\|769456_770479_-\|transposase	IS21-like element IS100 family transposase	A0A2L1IVA1	Escherichia_phage	1.9e-201	100.0
WP_002213759.1\|770589_771048_+\|transposase	IS200/IS605-like element IS1541A family transposase	NA	NA	NA	NA
WP_002209317.1\|771237_771444_-	DNA gyrase inhibitor YacG	NA	NA	NA	NA
770564:771156	attR	NA	NA	NA	NA
WP_002209318.1\|771629_772382_-	cell division protein ZapD	NA	NA	NA	NA
WP_002209319.1\|772378_772999_-	dephospho-CoA kinase	NA	NA	NA	NA
WP_002209320.1\|773294_774338_+	GMP reductase	A0A0N9Q9A5	Chrysochromulina_ericina_virus	6.3e-104	56.2
WP_002209321.1\|774764_775964_-	protein transport protein HofC	NA	NA	NA	NA
WP_002228310.1\|775960_777499_-	type II secretion system protein GspE	NA	NA	NA	NA
WP_002209323.1\|777491_777956_-	prepilin peptidase-dependent pilin	NA	NA	NA	NA
WP_002209324.1\|778158_779067_-	carboxylating nicotinate-nucleotide diphosphorylase	NA	NA	NA	NA
WP_002209325.1\|779179_779731_+	1,6-anhydro-N-acetylmuramyl-L-alanine amidase AmpD	NA	NA	NA	NA
WP_002209326.1\|780020_780875_+	beta-lactamase regulator AmpE	NA	NA	NA	NA
WP_002209327.1\|781307_782705_-	amino acid permease	NA	NA	NA	NA
WP_002216080.1\|783567_784332_+	pyruvate dehydrogenase complex transcriptional repressor PdhR	NA	NA	NA	NA
WP_002209329.1\|784527_787191_+	pyruvate dehydrogenase (acetyl-transferring), homodimeric type	NA	NA	NA	NA
WP_002209330.1\|787204_788734_+	dihydrolipoyllysine-residue acetyltransferase	NA	NA	NA	NA
WP_002209332.1\|789039_790464_+	dihydrolipoyl dehydrogenase	A0A2K5B2C5	Erysipelothrix_phage	1.0e-40	27.9
WP_002213775.1\|790706_791165_+\|transposase	IS200/IS605-like element IS1541B family transposase	NA	NA	NA	NA
WP_002209333.1\|791734_794332_+	bifunctional aconitate hydratase 2/2-methylisocitrate dehydratase	NA	NA	NA	NA
WP_002209334.1\|794630_794990_+	YacL family protein	NA	NA	NA	NA
WP_002209335.1\|795100_796009_-	aromatic amino acid DMT transporter YddG	NA	NA	NA	NA
WP_002209337.1\|796446_797241_-	adenosylmethionine decarboxylase	NA	NA	NA	NA
WP_002209338.1\|797318_798209_-	polyamine aminopropyltransferase	NA	NA	NA	NA
WP_002228215.1\|798325_798673_-	YacC family pilotin-like protein	NA	NA	NA	NA
WP_002209340.1\|798989_800591_+	multicopper oxidase CueO	A0A0C6DWA2	Mamastrovirus	8.9e-17	45.3
WP_002223179.1\|800801_801347_+	hypoxanthine phosphoribosyltransferase	A0A218MMB5	uncultured_virus	5.2e-17	33.1
WP_002209342.1\|801500_802163_-	carbonate dehydratase	NA	NA	NA	NA
WP_002209343.1\|802398_803325_+	ABC transporter ATP-binding protein	W6JKT0	Anomala_cuprea_entomopoxvirus	5.9e-21	30.7
WP_002209344.1\|803321_804092_+	ABC transporter permease	NA	NA	NA	NA
WP_002209347.1\|805761_806142_-	aspartate 1-decarboxylase	NA	NA	NA	NA
WP_002209348.1\|806552_807407_-	pantoate--beta-alanine ligase	NA	NA	NA	NA
WP_002209349.1\|807494_808292_-	3-methyl-2-oxobutanoate hydroxymethyltransferase	NA	NA	NA	NA
WP_002209351.1\|808560_809040_-	2-amino-4-hydroxy-6- hydroxymethyldihydropteridine diphosphokinase	S4VNV0	Pandoravirus	1.4e-18	43.2
WP_002228219.1\|809047_810556_-	polynucleotide adenylyltransferase PcnB	G3MAR3	Bacillus_virus	6.2e-28	30.6
WP_002228220.1\|810611_811577_-\|tRNA	tRNA glutamyl-Q(34) synthetase GluQRS	NA	NA	NA	NA
WP_002209354.1\|811856_812312_-	RNA polymerase-binding protein DksA	NA	NA	NA	NA
WP_002228221.1\|812481_813219_-	DNA/RNA nuclease SfsA	NA	NA	NA	NA
WP_002209356.1\|813331_813907_-	RNA 2',3'-cyclic phosphodiesterase	NA	NA	NA	NA
WP_002222096.1\|813947_816509_+	ATP-dependent helicase HrpB	A0A2H4UU36	Bodo_saltans_virus	3.5e-39	28.8
WP_002209358.1\|816617_819092_+	bifunctional glycosyl transferase/transpeptidase	NA	NA	NA	NA
WP_002209359.1\|819413_820208_+	Fe3+-hydroxamate ABC transporter ATP-binding protein FhuC	G9BWD6	Planktothrix_phage	2.1e-14	29.0
WP_002430132.1\|820207_821296_+	Fe(3+)-hydroxamate ABC transporter substrate-binding protein FhuD	NA	NA	NA	NA
WP_002209361.1\|821292_823290_+	Fe(3+)-hydroxamate ABC transporter permease FhuB	NA	NA	NA	NA
WP_002209362.1\|823663_824944_-	glutamate-1-semialdehyde 2,1-aminomutase	NA	NA	NA	NA
WP_002209364.1\|825324_826761_+	H(+)/Cl(-) exchange transporter ClcA	NA	NA	NA	NA
WP_002209365.1\|826896_827241_+	iron-sulfur cluster insertion protein ErpA	A0A2H4N7M3	Lake_Baikal_phage	3.5e-27	50.0
WP_002209366.1\|827542_828157_-	TRIC cation channel family protein	NA	NA	NA	NA
WP_002222100.1\|828156_828999_-	vitamin B12 ABC transporter substrate-binding protein BtuF	NA	NA	NA	NA
WP_002209368.1\|828998_829700_-	5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase	NA	NA	NA	NA
WP_002209369.1\|829993_831514_+	dGTPase	NA	NA	NA	NA
WP_002209370.1\|831711_833157_+\|protease	serine endoprotease DegP	A0A1B1IT49	uncultured_Mediterranean_phage	6.1e-25	29.5

DBSCAN-SWA_4

1158490 : 1202544

uncultured_virus(22.22%)

integrase,transposase,tRNA,protease

attL 1169881:1169895|attR 1198196:1198210

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_002208581.1\|1158490_1158970_-\|tRNA	Cys-tRNA(Pro)/Cys-tRNA(Cys) deacylase YbaK	NA	NA	NA	NA
WP_002208580.1\|1159233_1160043_-	TraB/GumN family protein	NA	NA	NA	NA
WP_002223301.1\|1160563_1163449_-	copper-exporting P-type ATPase CopA	A0A218MNH6	uncultured_virus	1.0e-111	36.8
WP_002208578.1\|1163655_1164075_+	Cu(I)-responsive transcriptional regulator	NA	NA	NA	NA
WP_002208577.1\|1164183_1164633_-	NfeD family protein	NA	NA	NA	NA
WP_002208576.1\|1164635_1165550_-	SPFH/Band 7/PHB domain protein	NA	NA	NA	NA
WP_002208575.1\|1165744_1166614_-	co-chaperone YbbN	NA	NA	NA	NA
WP_002208574.1\|1166690_1167467_-	SDR family oxidoreductase	NA	NA	NA	NA
WP_002208573.1\|1167853_1168489_-\|protease	multifunctional acyl-CoA thioesterase I/protease I/lysophospholipase L1	NA	NA	NA	NA
WP_002208572.1\|1168459_1169146_+	ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	1.6e-31	34.2
WP_002208571.1\|1169142_1171572_+	ABC transporter permease	NA	NA	NA	NA
1169881:1169895	attL	NA	NA	NA	NA
WP_002213775.1\|1171757_1172216_+\|transposase	IS200/IS605-like element IS1541B family transposase	NA	NA	NA	NA
WP_002208570.1\|1172325_1173390_-	5-(carboxyamino)imidazole ribonucleotide synthase	NA	NA	NA	NA
WP_002208569.1\|1173386_1173911_-	5-(carboxyamino)imidazole ribonucleotide mutase	NA	NA	NA	NA
WP_002208568.1\|1174206_1174929_-	UDP-2,3-diacylglucosamine diphosphatase	NA	NA	NA	NA
WP_002208567.1\|1174939_1175434_-	peptidylprolyl isomerase B	NA	NA	NA	NA
WP_002222677.1\|1175644_1177030_+\|tRNA	cysteine--tRNA ligase	A0A0G2Y344	Acanthamoeba_polyphaga_mimivirus	2.2e-40	28.5
WP_002213775.1\|1177376_1177835_+\|transposase	IS200/IS605-like element IS1541B family transposase	NA	NA	NA	NA
WP_002209775.1\|1177981_1178194_-	ribosome-associated protein YbcJ	NA	NA	NA	NA
WP_002209774.1\|1178208_1179075_-	bifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase FolD	A0A249XZQ2	Enterococcus_phage	2.2e-30	34.1
WP_002215270.1\|1179429_1179612_-	AlpA family phage regulatory protein	NA	NA	NA	NA
WP_002215268.1\|1179870_1180071_-	hypothetical protein	NA	NA	NA	NA
WP_002228356.1\|1180184_1180682_-	hypothetical protein	NA	NA	NA	NA
WP_002215266.1\|1180817_1181156_-	hypothetical protein	NA	NA	NA	NA
WP_079866998.1\|1181238_1181517_-\|integrase	tyrosine-type recombinase/integrase	A0A192Y6Q1	Salmonella_phage	4.2e-31	73.5
WP_002354559.1\|1181728_1181935_+	hypothetical protein	NA	NA	NA	NA
WP_002209770.1\|1182334_1182937_+	CDP-alcohol phosphatidyltransferase family protein	NA	NA	NA	NA
WP_002209769.1\|1182929_1183859_+	phosphatidate cytidylyltransferase	NA	NA	NA	NA
WP_002209768.1\|1183868_1184501_+	1-acyl-sn-glycerol-3-phosphate acyltransferase	NA	NA	NA	NA
WP_002209767.1\|1184497_1186261_+	bifunctional alpha/beta hydrolase/class I SAM-dependent methyltransferase	NA	NA	NA	NA
WP_002209766.1\|1186253_1187573_+	phosphatase PAP2/dual specificity phosphatase family protein	NA	NA	NA	NA
WP_002209765.1\|1187554_1187956_+	hypothetical protein	NA	NA	NA	NA
WP_002215253.1\|1188052_1188358_+	hypothetical protein	NA	NA	NA	NA
WP_001297096.1\|1188724_1189504_-	AAA family ATPase	A0A2L1IVB6	Escherichia_phage	4.5e-139	99.6
WP_000255944.1\|1189503_1190526_-\|transposase	IS21-like element IS100 family transposase	A0A2L1IVA1	Escherichia_phage	1.9e-201	100.0
WP_002209764.1\|1190619_1191513_+	LysR family transcriptional regulator	NA	NA	NA	NA
WP_002209763.1\|1191567_1192557_-	aldo/keto reductase	NA	NA	NA	NA
WP_002209762.1\|1192582_1193434_-	aldo/keto reductase	A0A2H4PQR8	Staphylococcus_phage	1.2e-49	41.1
WP_002209759.1\|1193906_1195535_+	hypothetical protein	NA	NA	NA	NA
WP_002228358.1\|1195613_1197995_-	glycoside hydrolase family 3 C-terminal domain-containing protein	NA	NA	NA	NA
WP_002209757.1\|1198153_1198684_-	GDYXXLXY domain-containing protein	NA	NA	NA	NA
1198196:1198210	attR	NA	NA	NA	NA
WP_002209756.1\|1198676_1200884_-	DUF4401 domain-containing protein	NA	NA	NA	NA
WP_002209743.1\|1201335_1202544_+\|transposase	IS256 family transposase	A0A218MNI5	uncultured_virus	5.4e-51	50.8

DBSCAN-SWA_5

1578003 : 1648699

Escherichia_phage(46.15%)

plate,tRNA,transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_002213759.1\|1578003_1578462_+\|transposase	IS200/IS605-like element IS1541A family transposase	NA	NA	NA	NA
WP_002208491.1\|1578604_1579114_-	PTS glucose transporter subunit IIA	NA	NA	NA	NA
WP_002208490.1\|1579162_1580890_-	phosphoenolpyruvate-protein phosphotransferase PtsI	A0A1V0SGR7	Hokovirus	3.0e-18	33.3
WP_002208488.1\|1580938_1581196_-	phosphocarrier protein Hpr	NA	NA	NA	NA
WP_002222180.1\|1581694_1582663_-	cysteine synthase A	A0A1X9I5F1	Streptococcus_phage	4.8e-74	51.8
WP_002213487.1\|1582819_1583554_-	sulfate transporter CysZ	NA	NA	NA	NA
WP_002227089.1\|1583802_1584789_+	cell division protein ZipA	NA	NA	NA	NA
WP_002213368.1\|1584879_1586892_+	NAD-dependent DNA ligase LigA	A0A0K2QQN8	Ralstonia_phage	1.7e-142	42.2
WP_002213369.1\|1586911_1587127_+	DUF3820 family protein	NA	NA	NA	NA
WP_002213372.1\|1587227_1587575_-	FlxA-like family protein	NA	NA	NA	NA
WP_002213374.1\|1587706_1588312_-	nucleotidyltransferase family protein	NA	NA	NA	NA
WP_002213775.1\|1589025_1589484_-\|transposase	IS200/IS605-like element IS1541B family transposase	NA	NA	NA	NA
WP_002222185.1\|1589676_1591092_-\|tRNA	glutamate--tRNA ligase	NA	NA	NA	NA
WP_002211622.1\|1592325_1593510_-	NupC/NupG family nucleoside CNT transporter	NA	NA	NA	NA
WP_002211621.1\|1593960_1595190_+	Nramp family divalent metal transporter	NA	NA	NA	NA
WP_002216909.1\|1595282_1595696_-	DUF2502 domain-containing protein	NA	NA	NA	NA
WP_002211618.1\|1595866_1596856_-	aldo/keto reductase	NA	NA	NA	NA
WP_002211617.1\|1596991_1597870_-	LysR family transcriptional regulator	NA	NA	NA	NA
WP_002211616.1\|1597972_1598449_+	multidrug/biocide efflux PACE transporter	NA	NA	NA	NA
WP_002211615.1\|1598629_1599601_+	glucokinase	NA	NA	NA	NA
WP_002211614.1\|1599678_1600926_-	DUF1479 domain-containing protein	NA	NA	NA	NA
WP_002211613.1\|1601191_1602427_+	alanine transaminase	NA	NA	NA	NA
WP_002211611.1\|1602690_1603215_+	cytochrome b	A0A0U2QLA7	Escherichia_phage	9.3e-24	47.1
WP_002211610.1\|1603309_1603741_-	hypothetical protein	Q7Y3V7	Yersinia_phage	2.4e-25	48.2
WP_002215847.1\|1604330_1605002_+	lipoprotein	NA	NA	NA	NA
WP_002215846.1\|1605028_1605385_+	DUF4810 domain-containing protein	NA	NA	NA	NA
WP_002211607.1\|1605381_1606038_+	DUF799 domain-containing protein	NA	NA	NA	NA
WP_002211606.1\|1606283_1606853_-	4Fe-4S binding protein	NA	NA	NA	NA
WP_002228419.1\|1606849_1607446_-	molecular chaperone	A0A077SLS7	Escherichia_phage	9.2e-44	49.2
WP_002211604.1\|1607927_1608704_-	dimethyl sulfoxide reductase anchor subunit family protein	A0A077SK59	Escherichia_phage	3.9e-42	41.4
WP_002211603.1\|1608705_1609323_-	dimethylsulfoxide reductase subunit B	A0A077SL61	Escherichia_phage	1.1e-87	68.3
WP_002228420.1\|1609334_1611761_-	dimethyl sulfoxide reductase subunit A	A0A077SK27	Escherichia_phage	6.9e-255	54.3
WP_002211601.1\|1612591_1613440_+	DUF4225 domain-containing protein	NA	NA	NA	NA
WP_002354621.1\|1613669_1614149_-	Hcp family type VI secretion system effector	NA	NA	NA	NA
WP_002211599.1\|1614615_1615140_+	DUF2127 domain-containing protein	NA	NA	NA	NA
WP_002211598.1\|1615212_1616262_-	ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	3.9e-21	32.4
WP_002215840.1\|1616258_1617845_-	iron ABC transporter permease	NA	NA	NA	NA
WP_002211596.1\|1617900_1618920_-	iron ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_002211594.1\|1619248_1620343_+	lytic murein transglycosylase B	NA	NA	NA	NA
WP_002211590.1\|1621608_1622211_+	LuxR family transcriptional regulator	NA	NA	NA	NA
WP_002215321.1\|1622568_1623051_-	DcrB-related protein	NA	NA	NA	NA
WP_002211588.1\|1623047_1624730_-	OmpA family protein	NA	NA	NA	NA
WP_002224806.1\|1624730_1625432_-	hypothetical protein	NA	NA	NA	NA
WP_002211586.1\|1625428_1626766_-	glycosyl transferase	A0A292GJ55	Xanthomonas_phage	2.0e-70	32.8
WP_002215319.1\|1626805_1627837_-	fimbrial protein	NA	NA	NA	NA
WP_002228423.1\|1627843_1629025_-	ImpA family type VI secretion system protein	NA	NA	NA	NA
WP_002211583.1\|1629123_1630149_-\|plate	type VI secretion system baseplate subunit TssG	NA	NA	NA	NA
WP_002211582.1\|1630148_1632029_-\|plate	type VI secretion system baseplate subunit TssF	NA	NA	NA	NA
WP_002215317.1\|1632811_1635487_+	type VI secretion system ATPase TssH	A0A223W0B1	Agrobacterium_phage	1.0e-81	32.3
WP_002211580.1\|1635687_1636233_+	type 1 fimbrial protein	NA	NA	NA	NA
WP_002211579.1\|1636389_1637151_+	fimbria/pilus periplasmic chaperone	NA	NA	NA	NA
WP_002215157.1\|1637278_1638829_+	fimbrial biogenesis outer membrane usher protein	NA	NA	NA	NA
WP_002211577.1\|1640082_1641273_+	fimbrial biogenesis outer membrane usher protein	NA	NA	NA	NA
WP_002211576.1\|1641257_1641866_+	type 1 fimbrial protein	NA	NA	NA	NA
WP_002211575.1\|1641970_1642495_+	type VI secretion system contractile sheath small subunit	NA	NA	NA	NA
WP_002211574.1\|1642518_1644021_+	type VI secretion system contractile sheath large subunit	NA	NA	NA	NA
WP_002211573.1\|1644346_1644832_+	type VI secretion system tube protein Hcp	NA	NA	NA	NA
WP_002211572.1\|1645105_1645645_+	type VI secretion system lipoprotein TssJ	NA	NA	NA	NA
WP_002211571.1\|1645648_1646998_+\|plate	type VI secretion system baseplate subunit TssK	NA	NA	NA	NA
WP_000255944.1\|1647676_1648699_+\|transposase	IS21-like element IS100 family transposase	A0A2L1IVA1	Escherichia_phage	1.9e-201	100.0

DBSCAN-SWA_6

1761020 : 1860688

104

Escherichia_phage(15.09%)

lysis,holin,transposase,tail,integrase,tRNA

attL 1771572:1771602|attR 1813297:1813327

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_002211184.1\|1761020_1761719_+\|tRNA	tRNA (adenosine(37)-N6)-threonylcarbamoyltransferase complex dimerization subunit type 1 TsaB	NA	NA	NA	NA
WP_002211183.1\|1761855_1762461_+	Slp family lipoprotein	NA	NA	NA	NA
WP_087768167.1\|1762461_1762569_-	gluconate 5-dehydrogenase	NA	NA	NA	NA
WP_002220632.1\|1763103_1764792_+	long-chain-fatty-acid--CoA ligase FadD	A0A2H4PQM9	Staphylococcus_phage	3.0e-31	28.9
WP_002211181.1\|1764951_1766073_+	ribonuclease D	NA	NA	NA	NA
WP_002211180.1\|1766309_1766579_-	cell division topological specificity factor MinE	NA	NA	NA	NA
WP_002211179.1\|1766582_1767395_-	septum site-determining protein MinD	NA	NA	NA	NA
WP_002220631.1\|1767419_1768106_-	septum site-determining protein MinC	NA	NA	NA	NA
WP_002211743.1\|1768826_1769099_+	YcgL domain-containing protein	NA	NA	NA	NA
WP_002215627.1\|1769239_1770325_+	lytic murein transglycosylase	NA	NA	NA	NA
WP_002211740.1\|1770395_1771052_+	fumarylacetoacetate hydrolase family protein	NA	NA	NA	NA
WP_002211739.1\|1771154_1771601_+	YcgN family cysteine cluster protein	NA	NA	NA	NA
1771572:1771602	attL	NA	NA	NA	NA
WP_002211738.1\|1771627_1772866_-\|integrase	site-specific integrase	Q20GI2	Phage_258-320	2.3e-121	53.3
WP_000255944.1\|1772935_1773958_+\|transposase	IS21-like element IS100 family transposase	A0A2L1IVA1	Escherichia_phage	1.9e-201	100.0
WP_001297096.1\|1773957_1774737_+	AAA family ATPase	A0A2L1IVB6	Escherichia_phage	4.5e-139	99.6
WP_002215632.1\|1774904_1775165_-	excisionase family protein	Q859D3	Escherichia_coli_phage	1.7e-10	42.9
WP_002211736.1\|1776189_1776636_+	recombination protein NinB	A0A2H4J8D9	uncultured_Caudovirales_phage	3.9e-47	62.5
WP_002211735.1\|1776709_1777315_+	recombination protein NinG	A0A1P8DTE0	Proteus_phage	2.8e-56	56.9
WP_002215636.1\|1777315_1777705_+	antitermination protein	A0A1W6JNX1	Morganella_phage	1.4e-45	68.8
WP_002215638.1\|1777708_1777927_+	ash family protein	NA	NA	NA	NA
WP_002211732.1\|1777975_1778539_+	Bro-N domain-containing protein	B6SD63	Bacteriophage	9.4e-30	58.0
WP_002393183.1\|1778623_1778800_-	hypothetical protein	NA	NA	NA	NA
WP_002211731.1\|1778962_1779172_+	hypothetical protein	NA	NA	NA	NA
WP_002215644.1\|1779168_1779444_-	hypothetical protein	NA	NA	NA	NA
WP_002430108.1\|1779689_1779887_+\|holin	phage holin family protein	B6SD15	Bacteriophage	4.9e-18	64.4
WP_002211730.1\|1779917_1780430_+	lysozyme	I6PBN2	Cronobacter_phage	9.7e-50	61.6
WP_002211729.1\|1780414_1780873_+\|lysis	lysis protein	A0A2H4JHL8	uncultured_Caudovirales_phage	4.9e-21	45.3
WP_002211727.1\|1781418_1782132_+	phage antirepressor KilAC domain-containing protein	Q5MBW0	Stx1-converting_phage	7.6e-69	60.2
WP_002211725.1\|1782588_1783224_+	hypothetical protein	I6S676	Salmonella_phage	7.2e-87	71.4
WP_002211724.1\|1783254_1783704_+	DUF2280 domain-containing protein	I6S1P9	Salmonella_phage	1.0e-47	72.9
WP_002211723.1\|1783707_1784292_+	hypothetical protein	A0A0R6PHH0	Moraxella_phage	4.8e-69	70.7
WP_002209743.1\|1784339_1785548_+\|transposase	IS256 family transposase	A0A218MNI5	uncultured_virus	5.4e-51	50.8
WP_002211722.1\|1785552_1786527_+	hypothetical protein	A0A1W6JNY3	Morganella_phage	2.3e-153	81.1
WP_002228445.1\|1786526_1787255_+	hypothetical protein	A0A1B0VMH0	Pseudomonas_phage	4.6e-61	51.4
WP_002228446.1\|1787273_1787915_+	DUF4055 domain-containing protein	A0A1B0VMH0	Pseudomonas_phage	3.8e-59	54.1
WP_002211721.1\|1787915_1789028_+	hypothetical protein	I6PD76	Cronobacter_phage	6.0e-121	58.2
WP_002211720.1\|1789149_1789923_+	hypothetical protein	A0A1B0VMG1	Pseudomonas_phage	2.8e-69	62.3
WP_002211719.1\|1789936_1791142_+	Ig-like domain-containing protein	A0A1B0VMF8	Pseudomonas_phage	1.8e-142	79.2
WP_002211718.1\|1791189_1791672_+	hypothetical protein	G8C7P9	Escherichia_phage	6.4e-27	46.1
WP_002211717.1\|1791668_1791923_+	hypothetical protein	J9Q7U0	Salmonella_phage	2.2e-18	53.1
WP_002211716.1\|1791924_1792275_+	hypothetical protein	I6PD77	Cronobacter_phage	6.9e-31	56.0
WP_002211715.1\|1792276_1792861_+	hypothetical protein	G8C7Q1	Escherichia_phage	3.6e-48	52.1
WP_002211714.1\|1792857_1793265_+	DUF4128 domain-containing protein	NA	NA	NA	NA
WP_002211713.1\|1793330_1794251_+	Ig-like domain-containing protein	I6PBN6	Cronobacter_phage	4.4e-61	49.1
WP_002211712.1\|1794263_1794575_+	hypothetical protein	I6PDG2	Cronobacter_phage	1.4e-30	58.3
WP_071525538.1\|1794622_1794883_+	DUF1799 domain-containing protein	A0A0S2SY90	Pseudomonas_phage	3.7e-13	50.0
WP_002211711.1\|1794883_1798387_+\|tail	phage tail tape measure protein	K7PMB9	Enterobacterial_phage	5.2e-118	33.2
WP_002211710.1\|1798389_1798731_+\|tail	phage tail protein	Q6UAW6	Klebsiella_phage	1.7e-21	50.0
WP_002213775.1\|1799036_1799495_+\|transposase	IS200/IS605-like element IS1541B family transposase	NA	NA	NA	NA
WP_002211709.1\|1799615_1800368_+\|tail	phage minor tail protein L	A0A1W6JNX9	Morganella_phage	9.4e-102	67.7
WP_002211708.1\|1800370_1801081_+	C40 family peptidase	K7P6F5	Enterobacteria_phage	1.3e-108	76.8
WP_002211707.1\|1801341_1801974_+	hypothetical protein	NA	NA	NA	NA
WP_002211706.1\|1802052_1802484_-	Arc family DNA-binding protein	G9L6D6	Escherichia_phage	2.5e-30	58.4
WP_002211705.1\|1802607_1802775_+	hypothetical protein	G9L6D7	Escherichia_phage	5.2e-13	61.8
WP_002211704.1\|1802848_1803856_+	Bro-N domain-containing protein	A0A2H4J0P1	uncultured_Caudovirales_phage	4.1e-36	33.0
WP_002214482.1\|1803954_1804506_+	zinc ribbon domain-containing protein	S4TR42	Salmonella_phage	9.5e-27	58.0
WP_002211701.1\|1804648_1804864_+	hypothetical protein	NA	NA	NA	NA
WP_002211700.1\|1804919_1805540_+\|tail	tail assembly protein	K7PGY0	Enterobacteria_phage	3.2e-55	57.0
WP_002211699.1\|1805581_1805746_+	hypothetical protein	NA	NA	NA	NA
WP_002359202.1\|1805714_1805936_-	hypothetical protein	NA	NA	NA	NA
WP_002211698.1\|1806111_1809315_+	host specificity protein J	F1C571	Cronobacter_phage	0.0e+00	60.5
WP_002211697.1\|1809314_1810313_+	hypothetical protein	NA	NA	NA	NA
WP_002211696.1\|1810329_1811247_+	hypothetical protein	NA	NA	NA	NA
WP_002211695.1\|1811257_1811677_+\|tail	tail fiber assembly protein	B6SCW7	Bacteriophage	5.7e-08	42.0
WP_002209743.1\|1811897_1813106_-\|transposase	IS256 family transposase	A0A218MNI5	uncultured_virus	5.4e-51	50.8
WP_002214492.1\|1813410_1814583_-	MFS transporter	NA	NA	NA	NA
1813297:1813327	attR	NA	NA	NA	NA
WP_002211693.1\|1814586_1815786_-	cysteine desulfurase	A0A1X7QGF3	Faustovirus	2.4e-38	29.6
WP_002211692.1\|1815802_1816543_-	hypothetical protein	NA	NA	NA	NA
WP_002214494.1\|1817634_1817991_+	hypothetical protein	NA	NA	NA	NA
WP_002227934.1\|1818407_1818938_-	disulfide bond formation protein DsbB	NA	NA	NA	NA
WP_002211689.1\|1819173_1820748_-	sodium/proton antiporter NhaB	NA	NA	NA	NA
WP_002211688.1\|1820991_1821711_+	fatty acid metabolism transcriptional regulator FadR	NA	NA	NA	NA
WP_002211687.1\|1821928_1823464_-	SpoVR family protein	NA	NA	NA	NA
WP_002211686.1\|1823929_1825234_+	D-amino acid dehydrogenase	NA	NA	NA	NA
WP_002216508.1\|1825249_1826452_-	multidrug effflux MFS transporter	S4TR35	Salmonella_phage	7.6e-29	29.1
WP_002211685.1\|1826716_1827586_-	pirin family protein	NA	NA	NA	NA
WP_002211684.1\|1827783_1828689_+	LysR family transcriptional regulator	NA	NA	NA	NA
WP_002211683.1\|1828723_1829842_-	DMT family transporter	NA	NA	NA	NA
WP_002216501.1\|1829949_1831224_-	YeaH/YhbH family protein	A0A140HLI1	Bacillus_phage	1.5e-11	37.1
WP_002211681.1\|1831373_1833308_-	protein kinase YeaG	NA	NA	NA	NA
WP_002430110.1\|1833751_1834501_+	MipA/OmpV family protein	NA	NA	NA	NA
WP_002211679.1\|1834573_1835449_-	D-hexose-6-phosphate mutarotase	NA	NA	NA	NA
WP_002224141.1\|1835762_1836758_-	glyceraldehyde-3-phosphate dehydrogenase	NA	NA	NA	NA
WP_002211677.1\|1837105_1837519_+	peptide-methionine (R)-S-oxide reductase MsrB	NA	NA	NA	NA
WP_002217933.1\|1837589_1837862_+	YeaC family protein	NA	NA	NA	NA
WP_002211676.1\|1837995_1838643_-	bifunctional nicotinamidase/pyrazinamidase	A0A2K9L6K4	Tupanvirus	1.8e-21	33.0
WP_002211675.1\|1838657_1839674_-	asparaginase	NA	NA	NA	NA
WP_002211674.1\|1839790_1841641_-	signal peptide peptidase SppA	NA	NA	NA	NA
WP_002211673.1\|1841803_1842355_+	NAD(P)H nitroreductase	NA	NA	NA	NA
WP_002211671.1\|1842579_1843626_+	selenide, water dikinase SelD	NA	NA	NA	NA
WP_002211670.1\|1843687_1845613_+	DNA topoisomerase III	A0A1X9I6W8	Streptococcus_phage	4.2e-37	30.4
WP_002211669.1\|1845609_1845900_+	DUF1496 domain-containing protein	NA	NA	NA	NA
WP_002211668.1\|1845912_1846299_-	pyrimidine (deoxy)nucleoside triphosphate diphosphatase	NA	NA	NA	NA
WP_002211667.1\|1846396_1847203_-	exodeoxyribonuclease III	NA	NA	NA	NA
WP_002211665.1\|1848012_1848873_+	LysR family transcriptional regulator	NA	NA	NA	NA
WP_002209743.1\|1849744_1850953_+\|transposase	IS256 family transposase	A0A218MNI5	uncultured_virus	5.4e-51	50.8
WP_002210667.1\|1850915_1851785_-	formyltetrahydrofolate deformylase	M4QRX9	Synechococcus_phage	5.5e-13	37.3
WP_002210666.1\|1851868_1852333_-	YchJ family protein	NA	NA	NA	NA
WP_002210665.1\|1853666_1854683_+	two-component system response regulator RssB	NA	NA	NA	NA
WP_002210664.1\|1854989_1856336_+	UDP-glucose/GDP-mannose dehydrogenase family protein	A0A127AXI2	Bacillus_phage	1.9e-81	38.3
WP_002223593.1\|1856770_1857178_-	DNA-binding transcriptional regulator H-NS	NA	NA	NA	NA
WP_002210659.1\|1857927_1858518_+	thymidine kinase	A0A1Z1LYD5	Serratia_phage	1.5e-54	55.8
WP_001297096.1\|1858886_1859666_-	AAA family ATPase	A0A2L1IVB6	Escherichia_phage	4.5e-139	99.6
WP_000255944.1\|1859665_1860688_-\|transposase	IS21-like element IS100 family transposase	A0A2L1IVA1	Escherichia_phage	1.9e-201	100.0

DBSCAN-SWA_7

2126530 : 2186655

Tupanvirus(18.18%)

coat,tRNA,transposase,protease

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_002211831.1\|2126530_2128918_-\|tRNA	phenylalanine--tRNA ligase subunit beta	NA	NA	NA	NA
WP_002211832.1\|2128931_2129915_-\|tRNA	phenylalanine--tRNA ligase subunit alpha	A0A2K9L3A8	Tupanvirus	7.6e-35	38.5
WP_152328947.1\|2130271_2130319_-	pheST operon leader peptide PheM	NA	NA	NA	NA
WP_002211833.1\|2130413_2130770_-	50S ribosomal protein L20	NA	NA	NA	NA
WP_002211834.1\|2130807_2131005_-	50S ribosomal protein L35	NA	NA	NA	NA
WP_002227898.1\|2131101_2131653_-	translation initiation factor IF-3	A0A2L0UZ54	Agrobacterium_phage	2.6e-16	33.7
WP_002211836.1\|2131656_2133585_-\|tRNA	threonine--tRNA ligase	A0A2K9L297	Tupanvirus	1.1e-127	37.1
WP_002216696.1\|2133975_2134188_+	KTSC domain-containing protein	A0A0K1LMB5	Caulobacter_phage	9.9e-09	42.0
WP_002211839.1\|2134946_2135198_-	hypothetical protein	NA	NA	NA	NA
WP_002211840.1\|2135516_2136200_+	MarC family NAAT transporter	NA	NA	NA	NA
WP_002216686.1\|2136321_2136984_-	transglycosylase SLT domain-containing protein	NA	NA	NA	NA
WP_002211842.1\|2137195_2138164_+	iron/manganese ABC transporter substrate-binding protein YfeA	NA	NA	NA	NA
WP_002211843.1\|2138160_2139051_+	iron/manganese ABC transporter ATP-binding protein YfeB	A0A1V0SKJ1	Klosneuvirus	2.9e-09	27.5
WP_002211844.1\|2139050_2139935_+	iron/manganese ABC transporter permease subunit YfeC	NA	NA	NA	NA
WP_002211845.1\|2139931_2140825_+	iron/manganese ABC transporter permease subunit YfeD	NA	NA	NA	NA
WP_002216683.1\|2140892_2141105_+	hypothetical protein	NA	NA	NA	NA
WP_002211846.1\|2141129_2142005_+	fructosamine kinase family protein	NA	NA	NA	NA
WP_002211847.1\|2142133_2142688_-	YniB family protein	NA	NA	NA	NA
WP_002220277.1\|2143098_2143764_+	hexitol phosphatase HxpB	NA	NA	NA	NA
WP_011566177.1\|2144014_2145223_-\|transposase	IS256 family transposase	A0A218MNI5	uncultured_virus	4.2e-51	50.8
WP_002210828.1\|2146593_2146944_-	cupin domain-containing protein	NA	NA	NA	NA
WP_002210829.1\|2147279_2148116_+	5-dehydro-4-deoxy-D-glucuronate isomerase	NA	NA	NA	NA
WP_002210830.1\|2148207_2148969_+	2-dehydro-3-deoxy-D-gluconate 5-dehydrogenase KduD	Q06VL0	Trichoplusia_ni_ascovirus	3.1e-20	32.9
WP_002210831.1\|2149304_2150972_+	pectate disaccharide-lyase	NA	NA	NA	NA
WP_002210832.1\|2151012_2151903_+	sugar ABC transporter permease	NA	NA	NA	NA
WP_002210833.1\|2151895_2152816_+	carbohydrate ABC transporter permease	NA	NA	NA	NA
WP_002210834.1\|2152829_2153957_+	ABC transporter ATP-binding protein	W5SAS9	Pithovirus	1.6e-12	26.5
WP_002210835.1\|2153972_2155265_+	carbohydrate ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_002210836.1\|2155562_2156273_+	porin	NA	NA	NA	NA
WP_002210837.1\|2156752_2157301_+	metal-dependent hydrolase	A0A127AVX7	Bacillus_phage	4.0e-09	32.9
WP_002210838.1\|2157504_2158896_+	L-cystine transporter	NA	NA	NA	NA
WP_002210839.1\|2159110_2159962_-	N-acetylmuramoyl-L-alanine amidase	A0A1W6DX33	Sphingobium_phage	1.3e-11	28.8
WP_002210840.1\|2160364_2161156_-	DNA-binding transcriptional regulator KdgR	NA	NA	NA	NA
WP_002210841.1\|2161342_2162509_-	oligogalacturonate lyase	NA	NA	NA	NA
WP_002210842.1\|2162835_2164203_+	MFS transporter	NA	NA	NA	NA
WP_002210843.1\|2164256_2165060_-	molecular chaperone	NA	NA	NA	NA
WP_002215120.1\|2165056_2166220_-	type 1 fimbrial protein	NA	NA	NA	NA
WP_002228489.1\|2166216_2168829_-	fimbrial biogenesis outer membrane usher protein	NA	NA	NA	NA
WP_002215118.1\|2168910_2169690_-	fimbrial chaperone	NA	NA	NA	NA
WP_002210846.1\|2169842_2170385_-	type 1 fimbrial protein	NA	NA	NA	NA
WP_002210847.1\|2171042_2171924_-\|protease	protease HtpX	NA	NA	NA	NA
WP_002210848.1\|2172397_2174470_-	carboxy terminal-processing peptidase	A0A0R6PIZ1	Moraxella_phage	4.0e-86	34.8
WP_002210849.1\|2174489_2175203_-	RNA chaperone ProQ	NA	NA	NA	NA
WP_002210850.1\|2175298_2175796_-	GAF domain-containing protein	NA	NA	NA	NA
WP_002367629.1\|2176027_2177275_+	membrane integrity lipid transport subunit YebS	NA	NA	NA	NA
WP_002216616.1\|2177243_2179895_+	PqiB family protein	NA	NA	NA	NA
WP_002210852.1\|2180373_2180928_+\|coat	spore coat U domain-containing protein	NA	NA	NA	NA
WP_002216613.1\|2180933_2181464_+\|coat	spore coat U domain-containing protein	NA	NA	NA	NA
WP_002216611.1\|2181484_2182042_+\|coat	spore coat U domain-containing protein	NA	NA	NA	NA
WP_002210856.1\|2182072_2182825_+	molecular chaperone	NA	NA	NA	NA
WP_002210857.1\|2183012_2185460_+	fimbrial biogenesis outer membrane usher protein	NA	NA	NA	NA
WP_002210858.1\|2185665_2186655_+\|coat	spore coat protein U domain-containing protein	NA	NA	NA	NA

DBSCAN-SWA_8

2753751 : 2864896

Escherichia_phage(14.29%)

lysis,transposase,plate,tRNA,protease

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_002211870.1\|2753751_2755779_+\|tRNA	methionine--tRNA ligase	A0A1V0SDF2	Indivirus	8.0e-55	27.1
WP_002213775.1\|2755942_2756401_-\|transposase	IS200/IS605-like element IS1541B family transposase	NA	NA	NA	NA
WP_002228565.1\|2756618_2757281_-	hypothetical protein	NA	NA	NA	NA
WP_002211975.1\|2757978_2759055_+	sugar ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_002211974.1\|2759072_2760326_+	LVIVD repeat-containing protein	NA	NA	NA	NA
WP_002213759.1\|2760579_2761038_-\|transposase	IS200/IS605-like element IS1541A family transposase	NA	NA	NA	NA
WP_002211973.1\|2761369_2762551_+	MFS transporter	NA	NA	NA	NA
WP_002211971.1\|2762792_2763200_+	CidA/LrgA family protein	NA	NA	NA	NA
WP_002211970.1\|2763196_2763892_+\|lysis	CidB/LrgB family autolysis modulator	NA	NA	NA	NA
WP_002211969.1\|2764217_2765102_+	cytidine deaminase	NA	NA	NA	NA
WP_002211968.1\|2765457_2767155_+	NAD-dependent malic enzyme	NA	NA	NA	NA
WP_002211966.1\|2767435_2768173_+	outer membrane permeability protein SanA	NA	NA	NA	NA
WP_002211965.1\|2768617_2769628_-	galactose/methyl galactoside ABC transporter permease MglC	NA	NA	NA	NA
WP_002211964.1\|2769648_2771169_-	galactose/methyl galactoside ABC transporter ATP-binding protein MglA	F2Y2R6	Organic_Lake_phycodnavirus	2.6e-10	29.9
WP_002211963.1\|2771398_2772391_-	galactose/glucose ABC transporter substrate-binding protein MglB	NA	NA	NA	NA
WP_002211961.1\|2773138_2774305_-	DUF418 family protein	NA	NA	NA	NA
WP_002211960.1\|2774359_2775022_-	GTP cyclohydrolase I FolE	R9TJA5	Vibrio_phage	5.8e-55	53.5
WP_002211959.1\|2775205_2776357_-	YbfB/YjiJ family MFS transporter	NA	NA	NA	NA
WP_002211958.1\|2776492_2777362_+	LysR family transcriptional regulator	NA	NA	NA	NA
WP_002211957.1\|2777635_2778775_+	S-(hydroxymethyl)glutathione dehydrogenase/class III alcohol dehydrogenase	E3SJ82	Synechococcus_phage	5.2e-35	29.9
WP_002211956.1\|2778795_2779638_+	S-formylglutathione hydrolase	NA	NA	NA	NA
WP_002227980.1\|2779894_2780107_+	peptide antibiotic darobactin C	NA	NA	NA	NA
WP_002215886.1\|2780190_2782551_+	darobactin export ABC transporter permease subunit	NA	NA	NA	NA
WP_002211952.1\|2782552_2783815_+	darobactin export ABC transporter periplasmic adaptor subunit	NA	NA	NA	NA
WP_002211951.1\|2783816_2784485_+	darobactin export ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	1.4e-35	40.0
WP_002211950.1\|2784494_2785805_+	darobactin maturation radical SAM/SPASM protein DarE	NA	NA	NA	NA
WP_002211949.1\|2786339_2787614_+	molybdopterin molybdotransferase MoeA	NA	NA	NA	NA
WP_002211948.1\|2787615_2788386_+	molybdopterin-synthase adenylyltransferase MoeB	NA	NA	NA	NA
WP_002209743.1\|2788521_2789730_+\|transposase	IS256 family transposase	A0A218MNI5	uncultured_virus	5.4e-51	50.8
WP_002211947.1\|2789773_2790427_-	hypothetical protein	NA	NA	NA	NA
WP_002227996.1\|2790654_2792250_-	ABC-F family ATPase	A0A2K9L0W2	Tupanvirus	6.1e-58	28.5
WP_002211945.1\|2792932_2793556_+	hypothetical protein	NA	NA	NA	NA
WP_002211944.1\|2793767_2795135_-	type VI secretion system ImpA family N-terminal domain-containing protein	NA	NA	NA	NA
WP_002211943.1\|2795159_2795612_-\|plate	type VI secretion system baseplate subunit TssE	NA	NA	NA	NA
WP_002214552.1\|2795611_2796193_-	type VI secretion system lipoprotein TssJ	NA	NA	NA	NA
WP_002211941.1\|2796167_2797253_-\|plate	type VI secretion system baseplate subunit TssG	NA	NA	NA	NA
WP_002211940.1\|2797216_2798980_-\|plate	type VI secretion system baseplate subunit TssF	NA	NA	NA	NA
WP_002211939.1\|2799200_2799656_-	hypothetical protein	NA	NA	NA	NA
WP_002211938.1\|2799670_2800729_-	PAAR domain-containing protein	NA	NA	NA	NA
WP_002211937.1\|2800746_2802348_-	type VI secretion system protein TssA	NA	NA	NA	NA
WP_002211936.1\|2802391_2805814_-	type VI secretion system membrane subunit	NA	NA	NA	NA
WP_002211935.1\|2805810_2807043_-	hypothetical protein	NA	NA	NA	NA
WP_002214564.1\|2809207_2809678_-	hypothetical protein	NA	NA	NA	NA
WP_002211932.1\|2809850_2812034_-	M23 family metallopeptidase	NA	NA	NA	NA
WP_002211931.1\|2812049_2812310_-	DUF2345 domain-containing protein	NA	NA	NA	NA
WP_002211930.1\|2812463_2813237_-	hypothetical protein	NA	NA	NA	NA
WP_002211929.1\|2813233_2815534_-	M23 family metallopeptidase	NA	NA	NA	NA
WP_002211928.1\|2815549_2817898_-	type VI secretion system tip protein VgrG	A0A2H4JCD4	uncultured_Caudovirales_phage	4.5e-17	32.1
WP_002211927.1\|2817900_2820543_-	type VI secretion system ATPase TssH	K4FB40	Cronobacter_phage	1.6e-92	31.6
WP_002210014.1\|2820930_2821422_-	Hcp family type VI secretion system effector	NA	NA	NA	NA
WP_002228049.1\|2821425_2823162_-	OmpA family protein	NA	NA	NA	NA
WP_002210015.1\|2823161_2823848_-	DotU family type IV/VI secretion system protein	NA	NA	NA	NA
WP_002211664.1\|2823844_2825197_-\|plate	type VI secretion system baseplate subunit TssK	NA	NA	NA	NA
WP_002215896.1\|2825208_2826753_-	type VI secretion system contractile sheath large subunit	NA	NA	NA	NA
WP_002211662.1\|2826795_2827296_-	type VI secretion system contractile sheath small subunit	NA	NA	NA	NA
WP_002213016.1\|2828284_2829133_-	ACP S-malonyltransferase	NA	NA	NA	NA
WP_002213017.1\|2829231_2829480_-	acyl carrier protein	NA	NA	NA	NA
WP_002228570.1\|2829517_2829958_-	lipocalin-like domain-containing protein	NA	NA	NA	NA
WP_002213024.1\|2830044_2830833_-	SDR family oxidoreductase	NA	NA	NA	NA
WP_002213025.1\|2830835_2831588_-	enoyl-CoA hydratase/isomerase family protein	NA	NA	NA	NA
WP_002213026.1\|2831589_2832309_-	enoyl-CoA hydratase/isomerase family protein	NA	NA	NA	NA
WP_002213028.1\|2832301_2833540_-	hydroxymethylglutaryl-CoA synthase family protein	NA	NA	NA	NA
WP_002213030.1\|2833555_2834293_-	SDR family oxidoreductase	NA	NA	NA	NA
WP_002213032.1\|2834294_2835578_-	beta-ketoacyl-[acyl-carrier-protein] synthase family protein	NA	NA	NA	NA
WP_002213034.1\|2835567_2836092_-	beta-hydroxyacyl-ACP dehydratase	NA	NA	NA	NA
WP_002213036.1\|2836355_2836574_-	hypothetical protein	NA	NA	NA	NA
WP_002213038.1\|2837304_2838051_+	SDR family oxidoreductase	F2NZ40	Diadromus_pulchellus_ascovirus	3.3e-14	31.4
WP_002213039.1\|2838204_2840622_+	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_002213046.1\|2844267_2844597_+	sulfurtransferase TusE	NA	NA	NA	NA
WP_002213049.1\|2844648_2844927_-	acylphosphatase	NA	NA	NA	NA
WP_002213052.1\|2845020_2846211_+	23S rRNA (cytosine(1962)-C(5))-methyltransferase RlmI	W6LLI2	Streptococcus_phage	2.1e-26	28.1
WP_002213054.1\|2846271_2846589_+	heat shock protein HspQ	NA	NA	NA	NA
WP_002213056.1\|2846697_2847114_-	CoA-binding protein	NA	NA	NA	NA
WP_002213058.1\|2847429_2848110_+	DUF2057 family protein	NA	NA	NA	NA
WP_002213060.1\|2848288_2848753_+	methylglyoxal synthase	NA	NA	NA	NA
WP_002221095.1\|2848813_2850868_-	DNA helicase IV	A7KV33	Bacillus_phage	1.5e-16	25.8
WP_002213062.1\|2851061_2851508_+	YccF domain-containing protein	NA	NA	NA	NA
WP_002213063.1\|2851537_2853676_+	TIGR01666 family membrane protein	NA	NA	NA	NA
WP_002213064.1\|2853777_2854413_-	TfoX/Sxy family DNA transformation protein	NA	NA	NA	NA
WP_002213065.1\|2854641_2855148_+	cell division inhibitor SulA	NA	NA	NA	NA
WP_002213066.1\|2855505_2856567_+	porin OmpA	NA	NA	NA	NA
WP_002213775.1\|2856756_2857215_+\|transposase	IS200/IS605-like element IS1541B family transposase	NA	NA	NA	NA
WP_002226586.1\|2857383_2857839_-	macrodomain Ter protein MatP	NA	NA	NA	NA
WP_002224683.1\|2858049_2859801_+\|protease	Lon protease family protein	NA	NA	NA	NA
WP_002220006.1\|2859869_2860388_+	bifunctional 3-hydroxydecanoyl-ACP dehydratase/trans-2-decenoyl-ACP isomerase	NA	NA	NA	NA
WP_002211286.1\|2860653_2860842_-	hypothetical protein	NA	NA	NA	NA
WP_000255944.1\|2861475_2862498_+\|transposase	IS21-like element IS100 family transposase	A0A2L1IVA1	Escherichia_phage	1.9e-201	100.0
WP_001297096.1\|2862497_2863277_+	AAA family ATPase	A0A2L1IVB6	Escherichia_phage	4.5e-139	99.6
WP_002213775.1\|2864437_2864896_-\|transposase	IS200/IS605-like element IS1541B family transposase	NA	NA	NA	NA

DBSCAN-SWA_9

3063068 : 3081433

Vibrio_phage(25.0%)

plate,coat,transposase,tail

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_002213775.1\|3063068_3063527_-\|transposase	IS200/IS605-like element IS1541B family transposase	NA	NA	NA	NA
WP_011566199.1\|3063727_3064732_-	nucleoid-associated protein YejK	A0A1V0E8C0	Vibrio_phage	1.5e-83	47.4
WP_002208836.1\|3064909_3065137_+	YejL family protein	NA	NA	NA	NA
WP_002208837.1\|3065164_3066961_+	DUF3413 domain-containing protein	NA	NA	NA	NA
WP_002230704.1\|3067191_3067575_+	DUF927 domain-containing protein	A0A1W6JPG0	Morganella_phage	7.8e-36	66.7
WP_002208839.1\|3067931_3069080_+	HNH endonuclease	NA	NA	NA	NA
WP_002208840.1\|3069092_3069581_+	hypothetical protein	NA	NA	NA	NA
WP_002208841.1\|3070280_3070643_+	hypothetical protein	NA	NA	NA	NA
WP_002208842.1\|3070768_3072205_-	6-phospho-beta-glucosidase	NA	NA	NA	NA
WP_002208843.1\|3072495_3073236_-	MurR/RpiR family transcriptional regulator	NA	NA	NA	NA
WP_002208845.1\|3073533_3074313_-\|tail	tail fiber protein	Q9MCR6	Enterobacteria_phage	7.1e-52	52.4
WP_002208846.1\|3074409_3074757_-	DUF2313 domain-containing protein	A0A2P9JZK7	Alteromonadaceae_phage	6.4e-21	41.3
WP_002215458.1\|3074753_3075014_-	DUF2313 domain-containing protein	NA	NA	NA	NA
WP_002208847.1\|3075010_3076147_-\|plate	baseplate J/gp47 family protein	B5TK75	Pseudomonas_phage	4.5e-31	30.5
WP_002208848.1\|3076150_3076606_-	phage GP46 family protein	A0A0C4UR04	Shigella_phage	4.3e-17	43.8
WP_002215460.1\|3076602_3077199_-\|plate	phage baseplate assembly protein	NA	NA	NA	NA
WP_002208850.1\|3077214_3078270_-\|tail	tail protein	M1PVV2	Vibrio_phage	1.3e-37	27.2
WP_002208852.1\|3078266_3079673_-	DNA circularization protein	Q8SBG8	Shigella_phage	2.1e-17	33.7
WP_002208853.1\|3079939_3081433_-\|coat	coat protein	NA	NA	NA	NA

DBSCAN-SWA_10

3159461 : 3195677

uncultured_virus(12.5%)

holin,tRNA,transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_002228612.1\|3159461_3160400_-\|tRNA	tRNA dihydrouridine(16) synthase DusC	NA	NA	NA	NA
WP_002210776.1\|3160699_3161629_-	DUF4097 domain-containing protein	NA	NA	NA	NA
WP_002213759.1\|3162043_3162502_-\|transposase	IS200/IS605-like element IS1541A family transposase	NA	NA	NA	NA
WP_002209743.1\|3164313_3165522_-\|transposase	IS256 family transposase	A0A218MNI5	uncultured_virus	5.4e-51	50.8
WP_002223532.1\|3165696_3166011_-	hypothetical protein	NA	NA	NA	NA
WP_002228617.1\|3166094_3166331_-	hypothetical protein	NA	NA	NA	NA
WP_016256670.1\|3166471_3166798_-	hypothetical protein	NA	NA	NA	NA
WP_002228620.1\|3166831_3167026_-	hypothetical protein	NA	NA	NA	NA
WP_002220152.1\|3168239_3169595_-	ATP-dependent RNA helicase RhlE	Q5GF26	Diachasmimorpha_longicaudata_entomopoxvirus	4.1e-55	35.6
WP_002220154.1\|3169985_3170696_+	transcriptional regulator CecR	NA	NA	NA	NA
WP_002220156.1\|3170747_3171734_+	secretion protein HlyD	NA	NA	NA	NA
WP_002228623.1\|3171747_3173490_+	ABC transporter ATP-binding protein	W6JKT0	Anomala_cuprea_entomopoxvirus	4.8e-24	34.6
WP_002220159.1\|3173494_3174670_+	ABC transporter permease	NA	NA	NA	NA
WP_002220162.1\|3174682_3175789_+	ABC transporter permease	NA	NA	NA	NA
WP_002220163.1\|3175827_3176154_-	EthD family reductase	NA	NA	NA	NA
WP_002220165.1\|3176164_3176392_-	N5,N10-methylene tetrahydromethanopterin reductase	NA	NA	NA	NA
WP_002220168.1\|3176946_3177858_+	LysR family transcriptional regulator	NA	NA	NA	NA
WP_002220169.1\|3177858_3178968_-	alkene reductase	NA	NA	NA	NA
WP_002220170.1\|3179315_3180680_-	sigma 54-interacting transcriptional regulator	Q6XM27	Feldmannia_irregularis_virus	1.3e-05	29.1
WP_002220171.1\|3180666_3182481_-	PAS domain-containing sensor histidine kinase	W8CYF6	Bacillus_phage	1.0e-16	28.4
WP_002220173.1\|3182838_3183312_+	zinc resistance sensor/chaperone ZraP	NA	NA	NA	NA
WP_002213759.1\|3184117_3184576_-\|transposase	IS200/IS605-like element IS1541A family transposase	NA	NA	NA	NA
WP_002214195.1\|3185504_3186368_-	xanthosine phosphorylase	Q5YBA4	Grouper_iridovirus	2.3e-51	40.7
WP_002214197.1\|3186713_3187562_+	DMT family transporter	NA	NA	NA	NA
WP_002214199.1\|3187599_3188493_-	LysR family transcriptional regulator	NA	NA	NA	NA
WP_002228035.1\|3188724_3190773_-\|holin	choline transporter	A0A2I7QNT1	Vibrio_phage	1.4e-19	28.5
WP_002218278.1\|3191137_3191734_+	transcriptional regulator BetI	NA	NA	NA	NA
WP_002218281.1\|3191791_3193264_+	betaine-aldehyde dehydrogenase	NA	NA	NA	NA
WP_002220180.1\|3193286_3194990_+\|holin	choline dehydrogenase	A0A1V0S9M4	Catovirus	9.4e-57	31.5
WP_011566203.1\|3195218_3195677_-\|transposase	IS200/IS605-like element IS1541B family transposase	NA	NA	NA	NA

DBSCAN-SWA_11

3258508 : 3324101

Escherichia_phage(20.0%)

integrase,tRNA,transposase,protease

attL 3258360:3258419|attR 3323494:3324211

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
3258360:3258419	attL	NA	NA	NA	NA
WP_002213759.1\|3258508_3258967_+\|transposase	IS200/IS605-like element IS1541A family transposase	NA	NA	NA	NA
WP_002210713.1\|3259190_3260390_+\|integrase	tyrosine-type recombinase/integrase	A0A1B5FPC6	Escherichia_phage	2.2e-108	50.2
WP_002210712.1\|3260468_3261557_+	DUF4297 domain-containing protein	NA	NA	NA	NA
WP_002215945.1\|3261607_3263278_+	hypothetical protein	NA	NA	NA	NA
WP_002215946.1\|3263439_3263667_-	hypothetical protein	NA	NA	NA	NA
WP_002210710.1\|3264474_3265362_+\|integrase	integrase domain-containing protein	NA	NA	NA	NA
WP_002210709.1\|3265354_3265555_+	AlpA family transcriptional regulator	A0A1V0E8E5	Vibrio_phage	1.6e-08	51.7
WP_002215949.1\|3265554_3266097_+	ash family protein	NA	NA	NA	NA
WP_002215950.1\|3266089_3267049_+	toprim domain-containing protein	A0A1W6JPG0	Morganella_phage	1.6e-50	41.0
WP_002210707.1\|3267045_3268134_+	AAA family ATPase	A0A2H4JFA4	uncultured_Caudovirales_phage	1.4e-114	60.4
WP_002210705.1\|3268482_3268797_-	putative addiction module antidote protein	NA	NA	NA	NA
WP_002215951.1\|3268802_3269120_-	type II toxin-antitoxin system RelE/ParE family toxin	A0A141GEX6	Brucella_phage	2.0e-13	48.1
WP_000255944.1\|3269724_3270747_+\|transposase	IS21-like element IS100 family transposase	A0A2L1IVA1	Escherichia_phage	1.9e-201	100.0
WP_001297096.1\|3270746_3271526_+	AAA family ATPase	A0A2L1IVB6	Escherichia_phage	4.5e-139	99.6
WP_002210703.1\|3271576_3271810_-	hypothetical protein	NA	NA	NA	NA
WP_002210701.1\|3272148_3273633_+	NCS1 family nucleobase:cation symporter-1	NA	NA	NA	NA
WP_002210700.1\|3273878_3274643_-	DNA polymerase III subunit epsilon	A0A1X9SH08	Bradyrhizobium_phage	1.9e-41	39.8
WP_002210699.1\|3274712_3275177_+	ribonuclease HI	J9Q745	Salmonella_phage	9.1e-47	53.9
WP_002210698.1\|3275231_3275951_-	class I SAM-dependent methyltransferase	NA	NA	NA	NA
WP_002210697.1\|3275995_3276751_+	hydroxyacylglutathione hydrolase	NA	NA	NA	NA
WP_002228041.1\|3276822_3278211_+	murein transglycosylase D	A0A2H4J9N7	uncultured_Caudovirales_phage	4.5e-09	36.8
WP_002220059.1\|3278252_3279035_-	endonuclease/exonuclease/phosphatase family protein	NA	NA	NA	NA
WP_002210693.1\|3279894_3280698_-	2,5-didehydrogluconate reductase DkgB	A0A1V0SKP9	Klosneuvirus	3.6e-27	29.2
WP_002220062.1\|3286838_3287405_-	D-glycero-beta-D-manno-heptose 1,7-bisphosphate 7-phosphatase	NA	NA	NA	NA
WP_002212161.1\|3287591_3288623_+	methionine ABC transporter ATP-binding protein MetN	G9BWD6	Planktothrix_phage	1.7e-32	35.4
WP_002212160.1\|3288615_3289269_+	methionine ABC transporter permease MetI	NA	NA	NA	NA
WP_002212159.1\|3289332_3290148_+	MetQ/NlpA family lipoprotein	NA	NA	NA	NA
WP_002212158.1\|3290265_3290673_+	Rcs stress response system protein RcsF	NA	NA	NA	NA
WP_002212157.1\|3290669_3291377_+\|tRNA	tRNA (N6-threonylcarbamoyladenosine(37)-N6)-methyltransferase TrmO	NA	NA	NA	NA
WP_002212156.1\|3291480_3293199_+\|tRNA	proline--tRNA ligase	NA	NA	NA	NA
WP_002212155.1\|3293332_3294016_-	envelope stress response activation lipoprotein NlpE	NA	NA	NA	NA
WP_002212154.1\|3294100_3294517_-\|tRNA	aminoacyl-tRNA hydrolase	NA	NA	NA	NA
WP_002212153.1\|3294519_3295068_-	YaeQ family protein	NA	NA	NA	NA
WP_002212152.1\|3295309_3295510_+	YaeP family protein	NA	NA	NA	NA
WP_002218374.1\|3295496_3295757_+	Rho-binding antiterminator	NA	NA	NA	NA
WP_002212150.1\|3296021_3296339_-	cytochrome c	NA	NA	NA	NA
WP_002212149.1\|3296575_3297958_-\|tRNA	tRNA lysidine(34) synthetase TilS	NA	NA	NA	NA
WP_002212148.1\|3297959_3298358_-	VOC family protein	NA	NA	NA	NA
WP_002212147.1\|3298541_3299501_-	acetyl-CoA carboxylase carboxyl transferase subunit alpha	NA	NA	NA	NA
WP_002228634.1\|3299513_3302996_-	DNA polymerase III subunit alpha	Q8W6C3	Saccharomonospora_phage	3.6e-204	37.2
WP_002212145.1\|3303158_3303755_-	ribonuclease HII	V5LS49	Emiliania_huxleyi_virus	3.8e-29	41.4
WP_002212144.1\|3303751_3304936_-	lipid-A-disaccharide synthase	NA	NA	NA	NA
WP_002212143.1\|3304939_3305728_-	acyl-ACP--UDP-N-acetylglucosamine O-acyltransferase	NA	NA	NA	NA
WP_002217656.1\|3305731_3306262_-	3-hydroxyacyl-ACP dehydratase FabZ	NA	NA	NA	NA
WP_002212141.1\|3306419_3307442_-	UDP-3-O-(3-hydroxymyristoyl)glucosamine N-acyltransferase	NA	NA	NA	NA
WP_002212140.1\|3307445_3307943_-	molecular chaperone Skp	NA	NA	NA	NA
WP_002212139.1\|3308100_3310488_-	outer membrane protein assembly factor BamA	NA	NA	NA	NA
WP_002212138.1\|3310524_3311880_-\|protease	sigma E protease regulator RseP	NA	NA	NA	NA
WP_002212137.1\|3311908_3312757_-	phosphatidate cytidylyltransferase	NA	NA	NA	NA
WP_002212136.1\|3312766_3313525_-	(2E,6E)-farnesyl-diphosphate-specific ditrans,polycis-undecaprenyl-diphosphate synthase	R9W0U9	Flavobacterium_phage	1.4e-23	40.7
WP_002212135.1\|3313748_3314945_-	1-deoxy-D-xylulose-5-phosphate reductoisomerase	NA	NA	NA	NA
WP_002212134.1\|3315158_3315716_-	ribosome recycling factor	NA	NA	NA	NA
WP_002212133.1\|3315851_3316577_-	UMP kinase	NA	NA	NA	NA
WP_002212132.1\|3316785_3317643_-	elongation factor Ts	NA	NA	NA	NA
WP_002221800.1\|3317770_3318496_-	30S ribosomal protein S2	NA	NA	NA	NA
WP_002212130.1\|3318930_3319722_+	type I methionyl aminopeptidase	NA	NA	NA	NA
WP_002212129.1\|3319781_3322463_+	bifunctional uridylyltransferase/uridylyl-removing protein GlnD	NA	NA	NA	NA
WP_002212128.1\|3322637_3323462_+	2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase	NA	NA	NA	NA
WP_002213759.1\|3323642_3324101_+\|transposase	IS200/IS605-like element IS1541A family transposase	NA	NA	NA	NA
3323494:3324211	attR	NA	NA	NA	NA

DBSCAN-SWA_12

3897321 : 3937333

Escherichia_phage(40.0%)

transposase,protease

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000255944.1\|3897321_3898344_+\|transposase	IS21-like element IS100 family transposase	A0A2L1IVA1	Escherichia_phage	1.9e-201	100.0
WP_001297096.1\|3898343_3899123_+	AAA family ATPase	A0A2L1IVB6	Escherichia_phage	4.5e-139	99.6
WP_086016626.1\|3899794_3900894_-\|transposase	IS3 family transposase	S5WIU1	Leptospira_phage	2.2e-46	39.2
WP_000255944.1\|3907154_3908177_+\|transposase	IS21-like element IS100 family transposase	A0A2L1IVA1	Escherichia_phage	1.9e-201	100.0
WP_001297096.1\|3908176_3908956_+	AAA family ATPase	A0A2L1IVB6	Escherichia_phage	4.5e-139	99.6
WP_002210151.1\|3910037_3910931_-	LysR family transcriptional regulator	NA	NA	NA	NA
WP_002210150.1\|3911192_3911897_+	pirin family protein	NA	NA	NA	NA
WP_002210149.1\|3912720_3913620_-	16S rRNA (cytidine(1402)-2'-O)-methyltransferase	M1PLC5	Streptococcus_phage	1.0e-49	44.4
WP_002228200.1\|3913682_3915656_+	penicillin-binding protein activator	NA	NA	NA	NA
WP_002210147.1\|3915739_3916093_+	YraN family protein	NA	NA	NA	NA
WP_002210146.1\|3916363_3916954_+	DnaA initiator-associating protein DiaA	A0A067XQR2	Caulobacter_phage	3.2e-12	32.0
WP_002210145.1\|3916964_3917540_+	divisome-associated lipoprotein YraP	NA	NA	NA	NA
WP_002210144.1\|3917746_3918472_-	monofunctional biosynthetic peptidoglycan transglycosylase	NA	NA	NA	NA
WP_002210143.1\|3918468_3919122_-	isoprenoid biosynthesis glyoxalase ElbB	NA	NA	NA	NA
WP_002210142.1\|3919363_3921700_-	aerobic respiration two-component sensor histidine kinase ArcB	A0A1V0SGX0	Hokovirus	9.9e-41	30.4
WP_002210140.1\|3921963_3922887_-	TIGR01212 family radical SAM protein	NA	NA	NA	NA
WP_002228691.1\|3923709_3928167_+	glutamate synthase large subunit	NA	NA	NA	NA
WP_002210138.1\|3928176_3929595_+	FAD-dependent oxidoreductase	NA	NA	NA	NA
WP_002224291.1\|3930035_3930521_+	hypothetical protein	NA	NA	NA	NA
WP_002216203.1\|3930673_3931189_-\|protease	ClpXP protease specificity-enhancing factor	A0A1S5R3H3	Pseudomonas_phage	3.6e-28	55.6
WP_002210135.1\|3931194_3931836_-	stringent starvation protein A	NA	NA	NA	NA
WP_002230558.1\|3932015_3932213_+	hypothetical protein	NA	NA	NA	NA
WP_002210133.1\|3932209_3932602_-	30S ribosomal protein S9	NA	NA	NA	NA
WP_002210132.1\|3932616_3933045_-	50S ribosomal protein L13	NA	NA	NA	NA
WP_002210131.1\|3933358_3934486_-	cell division protein ZapE	NA	NA	NA	NA
WP_002210130.1\|3934709_3935114_+	DUF1043 family protein	NA	NA	NA	NA
WP_002218066.1\|3935384_3936758_+\|protease	serine endoprotease DegQ	A0A1B1IT49	uncultured_Mediterranean_phage	7.4e-20	28.2
WP_002213775.1\|3936874_3937333_-\|transposase	IS200/IS605-like element IS1541B family transposase	NA	NA	NA	NA

Anti-CRISPR protein detection

Acr_ID: NC_008149.1|WP_002214494.1|1817634_1817991_+|hypothetical-protein

Click the colored protein region to show detailed information

Acr ID

Acr position

Acr size

Homology with known anti

Neighbor HTH/AcRanker

Neighbor Aca

In prophage

Protospacer in prophage

NC_008149.1|WP_002214494.1|1817634_1817991_+|hypothetical-protein

1817634_1817991_+

118 aa aa

1761020-1860688

yes

CRISPR ID	CRISPR type	Spacer info	Spacer location	Spacer length	Protospacer location	Mismatch
NC_008149_2	Orphan	2.4\|1221574\|32\|NC_008149\|CRISPRCasFinder,CRT	1221574-1221605	32	1788909-1788940	0

1. spacer 2.4|1221574|32|NC_008149|CRISPRCasFinder,CRT matches to NC_008149 position: 1788909-1788940, mismatch: 0

agactgatgcaagatggcggtatgcgtacaga	CRISPR spacer
agactgatgcaagatggcggtatgcgtacaga	Protospacer
********************************

2. NC_008118

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

86 : 64180

Salmonella_phage(91.67%)

tail,terminase,transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000255944.1\|86_1109_+\|transposase	IS21-like element IS100 family transposase	A0A2L1IVA1	Escherichia_phage	1.9e-201	100.0
WP_001297096.1\|1108_1888_+	AAA family ATPase	A0A2L1IVB6	Escherichia_phage	4.5e-139	99.6
WP_002211769.1\|2021_2630_-\|tail	tail fiber assembly protein	K7PMH7	Enterobacteria_phage	4.8e-64	62.2
WP_002211770.1\|2931_5820_-\|tail	phage tail protein	J9Q6E3	Salmonella_phage	4.5e-11	33.1
WP_002211771.1\|5900_6479_-	DUF4376 domain-containing protein	Q9LA61	Enterobacterial_phage	3.4e-27	38.8
WP_002214118.1\|6535_11167_-	DUF1983 domain-containing protein	J9Q713	Salmonella_phage	0.0e+00	88.6
WP_002211773.1\|11188_11776_-\|tail	tail assembly protein	J9Q7F8	Salmonella_phage	5.1e-103	92.8
WP_002211774.1\|11763_12561_-	C40 family peptidase	J9Q7R4	Salmonella_phage	1.4e-156	96.2
WP_002211775.1\|12553_13252_-\|tail	phage minor tail protein L	J9Q7Y5	Salmonella_phage	7.1e-136	99.1
WP_000440566.1\|13341_13677_-\|tail	phage tail protein	J9Q6E1	Salmonella_phage	5.7e-59	97.3
WP_002211776.1\|13718_18296_-	tape measure protein	J9Q712	Salmonella_phage	0.0e+00	90.5
WP_000952684.1\|18303_18528_-	hypothetical protein	J9Q7F7	Salmonella_phage	4.2e-34	100.0
WP_000163862.1\|18653_18971_-	hypothetical protein	J9Q7R3	Salmonella_phage	6.0e-50	98.1
WP_002211778.1\|19030_19777_-	Ig domain-containing protein	J9Q7Y4	Salmonella_phage	5.2e-129	98.8
WP_002211779.1\|19851_20235_-	hypothetical protein	J9Q6D8	Salmonella_phage	1.1e-66	98.4
WP_002211780.1\|20236_20710_-	hypothetical protein	J9Q711	Salmonella_phage	8.9e-82	99.4
WP_001027662.1\|20700_21045_-	hypothetical protein	J9Q7F6	Salmonella_phage	1.9e-57	100.0
WP_002211781.1\|21142_21976_-	hypothetical protein	J9Q7R2	Salmonella_phage	2.9e-152	99.6
WP_002211782.1\|21975_22410_-	hypothetical protein	J9Q7Y3	Salmonella_phage	3.1e-73	99.3
WP_002211784.1\|23120_23996_-	hypothetical protein	J9Q710	Salmonella_phage	8.5e-163	99.7
WP_002211786.1\|24945_26520_-	hypothetical protein	J9Q7R1	Salmonella_phage	2.4e-301	99.2
WP_002211787.1\|26553_27810_-\|terminase	terminase	J9Q7Y2	Salmonella_phage	1.8e-251	100.0
WP_002211788.1\|27812_28454_-	hypothetical protein	J9Q6D4	Salmonella_phage	1.2e-108	98.1
WP_000176291.1\|28649_28916_-	hypothetical protein	J9Q757	Salmonella_phage	1.3e-42	100.0
WP_002211789.1\|28925_29816_-	hypothetical protein	J9Q7I6	Salmonella_phage	6.2e-169	99.7
WP_002211790.1\|29821_30076_-	hypothetical protein	J9Q7U0	Salmonella_phage	2.0e-40	97.6
WP_002211791.1\|30068_30707_-	ATP-binding cassette domain-containing protein	J9Q807	Salmonella_phage	4.7e-110	98.1
WP_002211792.1\|30703_31372_-	ParB N-terminal domain-containing protein	J9Q6L1	Salmonella_phage	9.5e-114	98.2
WP_002228791.1\|31371_32070_-	ParB N-terminal domain-containing protein	J9Q756	Salmonella_phage	9.6e-125	98.7
WP_002211794.1\|32134_33694_+	DEAD/DEAH box helicase	J9Q7I4	Salmonella_phage	1.1e-293	99.0
WP_002214131.1\|33696_33975_+	hypothetical protein	J9Q7T9	Salmonella_phage	4.4e-41	97.8
WP_002211796.1\|34034_34457_+	hypothetical protein	J9Q806	Salmonella_phage	4.1e-62	85.0
WP_002214134.1\|34461_34989_+	transcriptional regulator	J9Q6L0	Salmonella_phage	6.4e-81	98.0
WP_002211799.1\|35312_35963_+	hypothetical protein	J9Q754	Salmonella_phage	4.1e-114	99.5
WP_002214137.1\|36047_36275_+	hypothetical protein	NA	NA	NA	NA
WP_002211801.1\|36913_37396_-	hypothetical protein	J9Q805	Salmonella_phage	5.1e-85	94.4
WP_002211802.1\|37601_37883_-	hypothetical protein	J9Q753	Salmonella_phage	6.1e-46	93.5
WP_002213759.1\|38082_38541_-\|transposase	IS200/IS605-like element IS1541A family transposase	D9CGB6	Hyperthermophilic_Archaeal_Virus_2	5.0e-13	35.3
WP_002214145.1\|38749_39319_-	hypothetical protein	J9Q7Z7	Salmonella_phage	5.8e-104	100.0
WP_002213303.1\|39331_40078_-	hypothetical protein	J9Q6J5	Salmonella_phage	4.1e-134	96.4
WP_002214148.1\|40067_41984_-	AAA family ATPase	J9Q741	Salmonella_phage	0.0e+00	98.6
WP_002213300.1\|42213_43299_-	metallophosphoesterase	J9Q7S9	Salmonella_phage	7.7e-206	98.6
WP_002213298.1\|43714_44737_+	ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_002214160.1\|45096_45741_-	hypothetical protein	J9Q739	Salmonella_phage	1.8e-122	98.1
WP_002214164.1\|46485_47550_+	replication protein RepA	J9Q7H0	Salmonella_phage	2.4e-188	98.6
WP_025471023.1\|48118_48331_-	hypothetical protein	J9Q7S8	Salmonella_phage	8.9e-34	94.3
WP_002227818.1\|48330_48666_-	hypothetical protein	J9Q7Z5	Salmonella_phage	5.2e-52	91.0
WP_002228796.1\|48662_48842_-	hypothetical protein	J9Q6J1	Salmonella_phage	5.8e-18	86.4
WP_002228797.1\|48882_49158_-	hypothetical protein	J9Q738	Salmonella_phage	1.7e-45	95.6
WP_002222869.1\|49225_49636_-	hypothetical protein	J9Q7G9	Salmonella_phage	4.1e-75	97.8
WP_002222868.1\|49619_49991_-	DUF2591 domain-containing protein	J9Q7S7	Salmonella_phage	4.0e-61	87.8
WP_002222866.1\|50144_50975_-	hypothetical protein	J9Q7Z4	Salmonella_phage	9.3e-127	98.6
WP_002213439.1\|50978_51179_-	hypothetical protein	J9Q6J0	Salmonella_phage	1.1e-25	97.0
WP_000920226.1\|52348_52615_-	hypothetical protein	J9Q7G8	Salmonella_phage	1.6e-40	100.0
WP_002225551.1\|52614_53559_-	exonuclease	J9Q7S6	Salmonella_phage	1.3e-180	99.0
WP_002213132.1\|53619_54648_-	hypothetical protein	J9Q7Z3	Salmonella_phage	1.3e-165	98.5
WP_011114024.1\|54767_55199_-	hypothetical protein	J9Q6I8	Salmonella_phage	2.2e-71	97.9
WP_002215095.1\|55419_55671_+	hypothetical protein	NA	NA	NA	NA
WP_002213141.1\|55743_56307_+	DNA-binding protein	J9Q7G7	Salmonella_phage	2.2e-63	64.6
WP_002425587.1\|56336_56762_-	hypothetical protein	J9Q7S4	Salmonella_phage	7.5e-72	100.0
WP_002221186.1\|56776_60301_-	DNA polymerase III subunit alpha	J9Q7Z2	Salmonella_phage	0.0e+00	99.2
WP_002211767.1\|60481_61717_-	AAA family ATPase	J9Q733	Salmonella_phage	3.0e-238	99.3
WP_002211766.1\|61813_64180_-	porphyrin biosynthesis protein	J9Q7G6	Salmonella_phage	0.0e+00	94.4

DBSCAN-SWA_2

72651 : 80363

Salmonella_phage(66.67%)

transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_002224363.1\|72651_72957_-	hypothetical protein	J9Q7S1	Salmonella_phage	3.2e-48	97.0
WP_002225462.1\|72953_73106_-	hypothetical protein	J9Q7Z1	Salmonella_phage	2.0e-19	96.0
WP_002224361.1\|73102_73318_-	hypothetical protein	J9Q6I3	Salmonella_phage	7.7e-33	98.6
WP_002233024.1\|73477_74515_-	DNA ligase	J9Q7G5	Salmonella_phage	1.8e-207	99.4
WP_001297096.1\|74590_75370_-	AAA family ATPase	A0A2L1IVB6	Escherichia_phage	4.5e-139	99.6
WP_000255944.1\|75369_76392_-\|transposase	IS21-like element IS100 family transposase	A0A2L1IVA1	Escherichia_phage	1.9e-201	100.0
WP_002228771.1\|76793_77270_-	hypothetical protein	J9Q7R9	Salmonella_phage	5.1e-77	95.6
WP_002224265.1\|77351_78146_-	hypothetical protein	J9Q7Z0	Salmonella_phage	3.7e-141	96.6
WP_002224263.1\|78398_79121_+	DUF4145 domain-containing protein	NA	NA	NA	NA
WP_002209743.1\|79154_80363_+\|transposase	IS256 family transposase	A0A218MNI5	uncultured_virus	5.4e-51	50.8

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. NC_008149

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection

Click the colored protein region to show detailed information

2. NC_008118

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection