CRISPRimmunity

Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NC_008312	Trichodesmium erythraeum IMS101, complete genome	50 crisprs	RT,cas14k,Cas14c_CAS-V-F,cas14j,Cas14u_CAS-V,PD-DExK,cas3,c2c9_V-U4,DinG,WYL	68	52	10	1

1. NC_008312

CRISPR-Cas detection and classification

Crispr_ID: NC_008312_1

• CRISPR_ID: NC_008312_1
• CRISPR_location: 16624-16758
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NC_008312_1

Consensus_repeat	Method
GTATTTTTGATAGAGTTTACTAAAATTCTAAATATAGATTTTTAAAG	CRISPRCasFinder

spacers of NC_008312_1

>1.1|16671|41|NC_008312|CRISPRCasFinder
AGAAGCAACAATTTACATAAAAGATAAATTGTCATAAATTG

CRISPR arrays and Neighbor proteins around NC_008312_1

CRISPR arrays

The CRISPR arrays of NC_008312_1

>merge|NC_008312|1|16624-16758|CRISPRCasFinder
GTATTTTTGATAGAGTTTACTAAAATTCTAAATATAGATTTTTAAAGAGAAGCAACAATTTACATAAAAGATAAATTGTCATAAATTGGTATTTTTGATAGAGTTTACTAAAATTCTAGATATAGATTTTTAAAG

>NC_008312|1|1|16624-16758|CRISPRCasFinder
GTATTTTTGATAGAGTTTACTAAAATTCTAAATATAGATTTTTAAAG	AGAAGCAACAATTTACATAAAAGATAAATTGTCATAAATTG
GTATTTTTGATAGAGTTTACTAAAATTCTAGATATAGATTTTTAAAG

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_008312.1|WP_011609935.1|26_1397_+|chromosomal-replication-initiator-protein-DnaA	unknown	unknown	gnl|CDD|234667
NC_008312.1|WP_011609941.1|17125_20872_+|ATP-binding-protein	unknown	unknown	gnl|CDD|379062
NC_008312.1|WP_011609942.1|21245_22433_-|TRC40/GET3/ArsA-family-transport-energizing-ATPase	unknown	unknown	gnl|CDD|223082
NC_008312.1|WP_011609938.1|10370_10973_+|DNA-polymerase-III-subunit-beta	unknown	unknown	gnl|CDD|235541
NC_008312.1|WP_011609944.1|23798_24329_-|pentapeptide-repeat-containing-protein	unknown	unknown	gnl|CDD|366316
NC_008312.1|WP_011609948.1|31433_32471_-|IS630-family-transposase	unknown	unknown	gnl|CDD|315923
NC_008312.1|WP_155994192.1|23489_23666_-|hypothetical-protein	unknown	unknown	unknown
NC_008312.1|WP_011609940.1|12894_15912_+|hypothetical-protein	unknown	unknown	unknown
NC_008312.1|WP_011609943.1|22679_23072_-|DUF2358-domain-containing-protein	unknown	unknown	gnl|CDD|370865
NC_008312.1|WP_011609947.1|28953_30639_+|dihydroxy-acid-dehydratase	unknown	unknown	gnl|CDD|234861
NC_008312.1|WP_011609946.1|25440_27636_-|DUF4912-domain-containing-protein	unknown	unknown	gnl|CDD|225867
NC_008312.1|WP_081432363.1|9092_9395_+|hypothetical-protein	unknown	unknown	gnl|CDD|235541
NC_008312.1|WP_081432519.1|11373_11829_-|IS630-family-transposase	unknown	unknown	gnl|CDD|315923
NC_008312.1|WP_011609939.1|11837_12341_-|helix-turn-helix-domain-containing-protein	unknown	unknown	gnl|CDD|379267
NC_008312.1|WP_011609950.1|36829_38158_+|tetratricopeptide-repeat-protein	unknown	unknown	gnl|CDD|380018
NC_008312.1|WP_011609949.1|33064_35353_+|PBP1A-family-penicillin-binding-protein	unknown	unknown	gnl|CDD|223815

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_008312.1|WP_011609935.1|26_1397_+|chromosomal-replication-initiator-protein-DnaA	gnl|CDD|234667	PRK00149, dnaA, chromosomal replication initiator protein DnaA.	0
NC_008312.1|WP_011609947.1|28953_30639_+|dihydroxy-acid-dehydratase	gnl|CDD|234861	PRK00911, PRK00911, dihydroxy-acid dehydratase; Provisional.	0
NC_008312.1|WP_011609942.1|21245_22433_-|TRC40/GET3/ArsA-family-transport-energizing-ATPase	gnl|CDD|223082	COG0003, ArsA, Predicted ATPase involved in chromosome partitioning [Cell division and chromosome partitioning].	4.15848e-134
NC_008312.1|WP_011609938.1|10370_10973_+|DNA-polymerase-III-subunit-beta	gnl|CDD|235541	PRK05643, PRK05643, DNA polymerase III subunit beta; Validated.	1.0018e-59
NC_008312.1|WP_011609944.1|23798_24329_-|pentapeptide-repeat-containing-protein	gnl|CDD|366316	pfam00805, Pentapeptide, Pentapeptide repeats (8 copies). These repeats are found in many cyanobacterial proteins. The repeats were first identified in hglK. The function of these repeats is unknown. The structure of this repeat has been predicted to be a beta-helix. The repeat can be approximately described as A(D/N)LXX, where X can be any amino acid.	1.10999e-06
NC_008312.1|WP_011609948.1|31433_32471_-|IS630-family-transposase	gnl|CDD|315923	pfam13358, DDE_3, DDE superfamily endonuclease. This family of proteins are related to pfam00665 and are probably endonucleases of the DDE superfamily. Transposase proteins are necessary for efficient DNA transposition. This domain is a member of the DDE superfamily, which contain three carboxylate residues that are believed to be responsible for coordinating metal ions needed for catalysis. The catalytic activity of this enzyme involves DNA cleavage at a specific site followed by a strand transfer reaction.	1.09878e-33
NC_008312.1|WP_011609950.1|36829_38158_+|tetratricopeptide-repeat-protein	gnl|CDD|380018	pfam17784, Sulfotransfer_4, Sulfotransferase domain. This family of proteins are distantly related to sulfotransferase enzymes. This protein in S. mansonii has been shown to be involved in resistance to oxamniquine and to have sulfotransferase activity.	3.54918e-30
NC_008312.1|WP_011609941.1|17125_20872_+|ATP-binding-protein	gnl|CDD|379062	pfam13191, AAA_16, AAA ATPase domain. This family of domains contain a P-loop motif that is characteristic of the AAA superfamily.	0.000174555
NC_008312.1|WP_011609943.1|22679_23072_-|DUF2358-domain-containing-protein	gnl|CDD|370865	pfam10184, DUF2358, Uncharacterized conserved protein (DUF2358). DUF2358 is a family of conserved proteins found from plants to humans. The function is unknown.	7.32185e-50
NC_008312.1|WP_081432363.1|9092_9395_+|hypothetical-protein	gnl|CDD|235541	PRK05643, PRK05643, DNA polymerase III subunit beta; Validated.	1.2098e-28
NC_008312.1|WP_011609946.1|25440_27636_-|DUF4912-domain-containing-protein	gnl|CDD|225867	COG3330, COG3330, Uncharacterized protein conserved in bacteria [Function unknown].	2.09002e-76
NC_008312.1|WP_011609939.1|11837_12341_-|helix-turn-helix-domain-containing-protein	gnl|CDD|379267	pfam13565, HTH_32, Homeodomain-like domain.	1.56839e-10
NC_008312.1|WP_011609949.1|33064_35353_+|PBP1A-family-penicillin-binding-protein	gnl|CDD|223815	COG0744, MrcB, Membrane carboxypeptidase (penicillin-binding protein) [Cell envelope biogenesis, outer membrane].	0
NC_008312.1|WP_081432519.1|11373_11829_-|IS630-family-transposase	gnl|CDD|315923	pfam13358, DDE_3, DDE superfamily endonuclease. This family of proteins are related to pfam00665 and are probably endonucleases of the DDE superfamily. Transposase proteins are necessary for efficient DNA transposition. This domain is a member of the DDE superfamily, which contain three carboxylate residues that are believed to be responsible for coordinating metal ions needed for catalysis. The catalytic activity of this enzyme involves DNA cleavage at a specific site followed by a strand transfer reaction.	3.80024e-17

Protein sequences

>NC_008312.1|WP_011609940.1|12894_15912_+|hypothetical-protein
MANELREGDKTPVDYSSLLKQILNELPTMNPFKVSSNKKILEINIDDIAACIAKTKVENPISNTISVRSATVNFASEKSFSEKIQEIKGCLETHFSSALQGENLVYFIEGLTTNLESFQGQANKLGLSYPFNEEYKGLQTKELILDSNKNGSDSILRFAKLTITVENTKKFISQLETGIKNHISDSFETDNQGEMEGALDILNSQINEESSNFNLLQKLVDQETLGKLKREAIITYLKYIEQNVDSKYKNTKGFIYLQDLIRRLKLIEEYLDEQTDDFEVYYAGVTVNYKDVFARGEAFDALPIIPIIEGNLGESRDKEVGKVQFTLGLKLKLNGKVQKDRGKTSFEYNLDIINPENSEHKAKLADPDIQSRESFAKKVLIRVFLYYFIFACDPPSLMNDELLYNPRLKFEQVLIDLKSSKHDDEKRKIFRGIVKGFSEYRVQEKVNSLCQFLINFINKKKRLPVYHENQVISISREILNKDLDSISIGDFFQEDWREGKKILKYIFIDKPGVNSYTLCQIPVIIKIEDIRYFQGDSNPKEFKFEYDIQGMKTLPMFWIPNTNPCLDNYKAYFEKEYKHILFYYDNKRLNQDRQNQEHFNSTQIFLYRFTWILLSYLCLYILLEECSEETKELLFIPMVRLHEGTPANPFHTEKFLADLSKLLCHIFNQKYLCNSQGFRVEMNKRPKNFQIRNGLNSLYSVLSKKFTLTDTSKFLNLEKLAIIIVSSRESDAKKNNKNSNDRIITLIGEVIGIEKLEDGSVKIQPLITFDNNYYLRKMYEKPPILNETVKDLYVQGYQNFLYVAQATYTSTLHITQQEQDEKLYFMSPTIIKDMKQGQKNIKIYPVFYDKYYVHPFKSLDSHSFYIQDTKQLMNISEDSSQEAVVFFNLFNGILVGNNERFYNGVISYSTLLGKFYPGVMDDADIREALVLDSQLKNDILQYLTFFHFSRFERQTKVSLKLDPYENIIGDKSVGALSIFPHLTENINFNALAFLIEVNKVVDVYF
>NC_008312.1|WP_011609939.1|11837_12341_-|helix-turn-helix-domain-containing-protein
MSGVVKIEINESVETLKKLLKSASTAQEKERLQTIYWLKTQTVETVKEIAIMLGRNRVTVQKWLGKYRTGGLNLLLEPKKNLGGRPSSIPPNVIEKLEAELQNPEGFQSYGEIQQWLTTCFDIELSYRTVHQLVRYKLKSKLKVPRPNHIKQNKEAQENFKKNSHLN
>NC_008312.1|WP_081432519.1|11373_11829_-|IS630-family-transposase
MKLINKYSENQLPIRYWCQDETRIGLKTITGKVITACGVKPIGLYQWLFKYLWLYGLVEPKTGDSFFYEFSHLDTPCFERFLELFSQTYPEEIHIIQLDNGRGHLGNDLSIPDHIILLFQPPYCPEVNPIERLWKEVKKFLKNRVFDSLDF
>NC_008312.1|WP_011609938.1|10370_10973_+|DNA-polymerase-III-subunit-beta
MQEGEEEIEEVTEIEEFEVTIPAKALREVERMISMGKSGSSVTLKFDENQVIFELGKQRLTSRKLEGQYPAYQQLLPNQFTNQINVDRKKFLGAVERIAVLADQKNNILKCTIDSVNQEISLSVDAQDVGSGRESMAAQISSDEPEEIAFNVKYLIEGLKAIPSASEISIQLNTATTPVVLNPLGGFQMTYLIMPVQLRS
>NC_008312.1|WP_081432363.1|9092_9395_+|hypothetical-protein
MTIDDDAGEAIATLTSTSGRYQVRGMGGEEYPELPNVEAGEVINLQSEALIDGLRGTLFATSPDETKQVLTGVHLKVQTDGLEFVATDGHRLAIVVRLVG
>NC_008312.1|WP_011609935.1|26_1397_+|chromosomal-replication-initiator-protein-DnaA
MEIYLDNLWDQVLERLQLQLSKPTFETWIKTATAEQLENNCLVIRAPNPFARNWLQKYYIKTIADVVHDILGYPVEIYLTTFLVEDSRKNDSGLIWSEHKSVNILGENLSIPKPLPANLNAKYMFSRFVVGPNNRMAHAASLAVAESPGQEFNPLFLCGGVGLGKTHLMQAIGHYRLDIFPHSQIFYVSTEKFTNDLIAAIRKDSLQGFREHYRAADVLLVDDIQFIEGKEYTQEEFFHTFNTLHEAGKQVVLASDRPPNQIPSLQERLCSRFSMGLIADIQAPDLETRMAILLKKSEYENMVLPRDVIEYIATRYPSNIRELEGALTRVVTYISISGLPMTVENIAPILNPKTEKLEASPEAVIKVVSENFNLSIEDLKGSSRKREITLARQVGMYLMRQHTDLSLPKIGEVFGGKDHTTVLYSCDKISQLQNSDLNLVQTIRQLSDRINFSSRH
>NC_008312.1|WP_011609941.1|17125_20872_+|ATP-binding-protein
MKITDNLGFLFEVGFNIGILADIQHQKYQNNFGDLYVRDLQQLKLPRMVKRMSQNHSIIDPESIKNLEIWSRYFILKGFLGGLIFFREYIKSTKWNLEPKKLKILYYQCCFHGDNSLGTNNKDKLLGIEELLSQFLSVDDLNTNLNRYVNQYLGKKGEFLQADTLILLGDDQQLRIICVDMSIFSVASEKDLVPLNDNKLNNLRKILMTDIKHIHSKSVFSKLRIDTGNTKDFDFVFSSDFKSFFTAFKRKDKETTKLIQAGAYAESFYNFLLKETQIITDKKSVLFNIVGYSDRNISTLCLRPENLNILTTCSEIYKKEDKNKETKVARRKVLDLIKNRAVFSFINGKALTENLKTKKLNFSGDGIARVIHEEKLNDFVNSIDVISDKLAAKLGLKLGLNLRDAHAELIEKALISDNTFVFLTGNPGIGKTTAIANFLKSHLEEGFLFFYISPRIQVNLDLIHKFKSENAQDQELFDDRLFCINTNSIIIQENDNYSTVRYYSNQRQDDFTSKNVRFINYNSQAEPRKQRQRNFHRITVDKIENRKKITAGVLDSVCKGIYAIINDKISNNIVATVSTQSLKITPNGRDTIEHLKTIFKSTYDRKRGVNPDKMYEISQRIKHLFIMIDEITGDDSGVHFLKGINKFLGQYQLTNSEYGFNTKVIVADASIVEQEVIQQHLSQESPEPDKIYFRAAKSQAEALSVQDFQFKNKRAVTINANSYPASSLNITYKVFIQSINFNQYDWKFKEKNQLTKEVDLEILSDIKYFLENYSSSQLLVYIQNKKRLKSLIKNIKESHKNFDEYTDYLEIHASLYDEKRKKIDKYKQDVKIVFMTSSASRGLSFPKAKKILVEIPRFQIEKNLMEVIQVIYRARGQYQENGKKITLDDQEKEIIFYFSDSAIYYPKDNDTSLENYDEERTLSLEESTMNLLDMLLILKLSIMTRIVGAGNLGSKKFLMVPIGGKSISTAGNSFSEKMTNLIRELKNEHNRHPEKQSLQYVYSSLTQILKEAVFSLPNSNSDSKNITYLSLIGFLKTELPTLFNRLDKFLNFGNIETGHLTGNLLVVPIYNQALEETYQIELENQIRRFANNELVNKMLSIMKSKDYPPNIKSAIESPLELIKILKGDKGNINTTQWFEQNSNNLDQYYAVPLFVFISGELMSKYFKQELEEEEEETAFRTLLSKYIHSLYPAYNTLPIGRKYKEFPFIVFRSYSLKEIREKIYSDRYLLTSNELNVLNLILSREERS
>NC_008312.1|WP_011609942.1|21245_22433_-|TRC40/GET3/ArsA-family-transport-energizing-ATPase
MRVILMTGKGGVGKTSVAASTGLRCAELGHKTLVLSTDPAHSLADSFDMEMSHEPRKVKENLWGAELDALMELEGNWGAVKRYITQVLQARGLDGVQAEELAILPGMDEIFGLVRMKRHYDEGEYDVLIIDSAPTGTALRLLSLPEVGGWYMRKFYKPLQGMSVALRPLFEPIFKPITGFSLPDKEVMDAPYEFYEQIEALEKVLTDNTKTSVRLITNPEKMVIKESLRAHAYLSLYNVSTDLVVANRIIPDSVSDPFFKKWKENQQQYRQEIHDNFRPLPVKEVPLYSEEMCGLAALKRLKETLYGDEDPSQVYYKENTVKVVQEKGNYNLELYLPGIPKEKIQLNKTGDELNIRIGNHRRNLVLPQALASLQPVGAKMEDDYLKIRFAEVAKV
>NC_008312.1|WP_011609943.1|22679_23072_-|DUF2358-domain-containing-protein
MDIISRLKQDYQKFPADQTYSIYAENVYFEDPLNKFRGIERYQKMIGFMNNWFNDIKLDLHDISQSGNVIKTRWTLSWTAPVPWKPPMAIPGWSELKLNADGLINSHIDYWDISRLDVLKQLFQLRSFPV
>NC_008312.1|WP_155994192.1|23489_23666_-|hypothetical-protein
MSLRKQIIRAIAKGKKKFFPPGSLFFLSFGGSSFAKASSDFFSISVYGGLENILLSKF
>NC_008312.1|WP_011609944.1|23798_24329_-|pentapeptide-repeat-containing-protein
MPLLELTLTQLWNKQTNAKLTHNIYEEIGGVKKSIANHAKEVYEQLNDEKRKKLEQIFIQLINLENLKAYTLRVKNYTNLGEDNWELITYLNSENISLVIINYNLRKILRDNGSNLSEPNLEEDKFNSAHAPKAQFQVADISKADLSNANLDGTNFSRAKLNEANFSKAYMPNVNC
>NC_008312.1|WP_011609946.1|25440_27636_-|DUF4912-domain-containing-protein
MVQERPPLEEMTLRQLRKVASELGISRYSRMRKAQLLAAVIEAQGMNNLSSAPLSKLEVQERAEAKKFESGEENNIDDFFSSVDEGLTDLPNGYAKSKIVLMPRDPEWAYAYWDISNELKEELRSQGGQQLALRTYDVTDINLDSQSPHSIQEYPCDELAREWYIPIPVSDRNYTVEIGYRCADGRWLVLSRSEEVNIPPVYPSDWIDEQFITVSWDEDLRGKTFMELFPASRQITFHDNHDDIYQGMFGIAEAEDKRVSGSMFGSVQMVPGSGQMIEETLSSYAMVSGLGMWASGSNVSCGNQMMSGVGQTMSGVGLNASGVGLTASGVGLTASGVGLTASGVGLNASGVGLTASGVGLNASGVGLTASGVGLNASGVGLTASGVGLNASGVGLTASGVGLNASGVGLTASGVGLNASGVGLTASGVGLNASGVGLTASGMGMNMSGVGLTASGMGMNMSGVGLTASGVGMNMSGVGLTASGMGMNMSGVGLTASGMGMNMSGVGLTASGMGMNMSGVGLTASGMGMNMSGVGLTASGMGMNMSGVGLTASGMGMNMSGVGLTASGMGMNMSGVGLTASGMGMNMSGVGLTASGMGMNMSGVGLTASGMGMNMSGVGLTASGMGMNMSGIAGSIPPIRPRKFWLVADAELIIHGATEPDATVTIGGRPIKLNPDGTFRFQMAFPDGLIDYPIMAVAVDGEQNRSIHMQFTRETPERHTNKKEEAILEWMS
>NC_008312.1|WP_011609947.1|28953_30639_+|dihydroxy-acid-dehydratase
MPENLRSQLVTKGVQRAPNRAMLRAVGFEDSDFTKPIIGVANAHSTITPCNMGINDLAMRAVSGVKEAGGMPQIFGTITISDGISMGTEGMKYSLVSRDVIADSIETVCNGQTMDGVLAIGGCDKNMPGAMIAIARMNIPAIFVYGGTIKPGNYNGKDLTVVSAFEAVGEYSAGKIDETELTEVERRACPGAGSCGGMFTANTMSSAFEAMGMSLMYSSTMAAEDAEKADSTEKSAHVLVEAIRKQILPSQIITRKAIENAISVIMAVGGSTNAVLHLLAIAYAANVKLSLDDFEIIRARVPVLCDLKPSGKYVTTNLHQAGGIPLVMKMLLEHDLLHPDALTITGKTIGEQLTNIPSEPPSNQDVIRPWNNPMYAQGHLAILKGNLATEGAVAKITGVKNPEITGLARVFDSEEACLEAILAGKIQAGNIIVVRYEGPKGGPGMREMLAPTSAIIGAGLGDKVGLITDGRFSGGTYGMVVGHVAPEAAVGGTIALVKEGDMITIDAHKRLLQLNISDEELEKRRQVWKPRKPQYTRGVLAKYAKLVSSSSVGAVTDAGLG
>NC_008312.1|WP_011609948.1|31433_32471_-|IS630-family-transposase
MNIIDKLNNFINQTKESKEIKRALAVKMTLSGKSYHEVKELLNVSHSFISEWKNQALFHGVESLRLQYQGRQGYLKTVEKEKTIEWLRAQDYLRLSDLKNYLQEQYDVVFESNQSYYNLFKEAGISWKKTQKKNPAKNDELVEVKRKEIEEFLAKWQPEIETGKLTVFMIDECHLLWGDILGYAWGKTDERIEIAIKNEKERQTYYGALDYKTKEFLVQEYESGNTKNTIEFIKYLQKQRPGNKLAIFWDGATYHNSQEFREYLMTINQYLSEEELLINCTRFAPNAPEQNPVEDIWLQTKNFSITFYHLCSSFKVVKWLFKFFADGQIFNFPKLFQYEILPQPT
>NC_008312.1|WP_011609949.1|33064_35353_+|PBP1A-family-penicillin-binding-protein
MNYSQPLRNSQTILGNITQMIKTIHASVNFSRLAIRPNARVPELWIEEGKATPTKKYPLLGDRYLLGRSSQACDIVIRNHLISKIHLSISRNSNKADAPYIIKDENSRNGLYNGKKKIYSLILRHGDILTLGPPALADTVKVRYIYPPAWYTQAFRYSLLGISGFTALVSLIILLEWTKFQVYPLPNPITGPVVIYARDGQTPLRPVYTNSHYELGRISKFSKYLPDAVIASEDSRFYWHIGIDPIGVVRAILTNLRSDGRREGGSTVTQQLARSIFRDYVGTEDSASRKIREAIAALKLETFYSKDDLLLAYLNKVYLGLDLYGFEDAARFYFGKSAQNLTLSEAATLVGILPAPNIFNPVQNYQIAIEKRDGVLYRMLSLGMIDQQEADRARRSLIEINPKAIEIIQSTIAPYYYSHVFSELENLLGEDLAKEGNFIVQTALNPEIQSYAERTLQDTINQVGSYASFSQGAIVTIDSRNGEVITLIGGVDYKKSQFNRATQAQRQPGSTFKVFAYAAAIEKGIPPKKLYSCSSFGWMGQTYEGCQRSSGNRNMYDGLALSENVVALRVAQQVGLDRVVKMAKGLGIKSQLSAVPGLILGQSEVNVLEMTGAYGVFANGGVANKPHTIRKIIDSSDCRDRNNIYTCRCIYSYIPDTNCENPKGDIQANQSIIQPYIASIMTQMLQDVIRHGTGRSANLGWGEAGKTGTTNQGIDIWFIGYIPNESMVTGIWLGNDDNSPTYGSSEQAAQLWGNYMKKVVNK
>NC_008312.1|WP_011609950.1|36829_38158_+|tetratricopeptide-repeat-protein
MPHTNQTERKYYSHYSDDQIRQIVVEKYKTCLEKFGYLFELEIKYKFDKNYQIKISIPIYKKFMVPVINNFISKANKLKKEEKLDEAIALYKQAIELNPGFPWYYYELGETLTEKGDLDEAIAQFFQATKINPNSAWFCYELAKALQKKGELNQAINYYRQAIESNPDFYGFYNSLGCCFFQNKNYHQAIINFLIALELNSSSVISYEYLYQVYLQLGLTKKCIDNLFGRFKQPSQKPTLTIRIKEKSVNSKQELSKTKIFGIGLGKTGTTTLGACLNNLGYKHYGWYTLTNHKLLYQIKLDNFDDVHRVVNQYDCFEDYPWPLIYKWLDQKYPNSKFILTIRKCSQTWFKSCLNHYFRLQDRAAYLYDLIYGLGHPQNCSDEYINFYESHNQQVIDYFQSKPDKLLIICWEKGDSWDKLCGFLGKTVPEILLPHLMKSQTN

Crispr_ID: NC_008312_2

• CRISPR_ID: NC_008312_2
• CRISPR_location: 438079-438234
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NC_008312_2

Consensus_repeat	Method
CCCATTTTTATTTCCATCGTTAAACATAAAATAGAAGTTAAACACATACATAA	CRISPRCasFinder

spacers of NC_008312_2

>2.1|438132|50|NC_008312|CRISPRCasFinder
AAAACCATTGACTGGCTTTGTTTTGTTTCTGTTTATTTTCCTATTTTTTC

CRISPR arrays and Neighbor proteins around NC_008312_2

CRISPR arrays

The CRISPR arrays of NC_008312_2

>merge|NC_008312|2|438079-438234|CRISPRCasFinder
CCCATTTTTATTTCCATCGTTAAACATAAAATAGAAGTTAAACACATACATAAAAAACCATTGACTGGCTTTGTTTTGTTTCTGTTTATTTTCCTATTTTTTCCCCATTTTTATTTCCATCGTTAAACCTAAAATAGAAGTTAAACACATACATAA

>NC_008312|2|2|438079-438234|CRISPRCasFinder
CCCATTTTTATTTCCATCGTTAAACATAAAATAGAAGTTAAACACATACATAA	AAAACCATTGACTGGCTTTGTTTTGTTTCTGTTTATTTTCCTATTTTTTC
CCCATTTTTATTTCCATCGTTAAACCTAAAATAGAAGTTAAACACATACATAA

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_008312.1|WP_011610171.1|452824_455425_+|M1-family-metallopeptidase	unknown	unknown	gnl|CDD|223385
NC_008312.1|WP_011610170.1|451429_452728_-|protein-glutamate-O-methyltransferase-family-protein	unknown	unknown	gnl|CDD|376673
NC_008312.1|WP_011610161.1|438502_439606_-|glycine-oxidase-ThiO	unknown	unknown	gnl|CDD|274092
NC_008312.1|WP_011610154.1|427228_427843_-|heme-copper-oxidase-subunit-III	unknown	unknown	gnl|CDD|224758
NC_008312.1|WP_011610151.1|422370_423588_+|MFS-transporter	unknown	unknown	gnl|CDD|341027
NC_008312.1|WP_044136274.1|442806_443052_-|hypothetical-protein	unknown	unknown	unknown
NC_008312.1|WP_011610168.1|447470_448331_-|hypothetical-protein	unknown	unknown	gnl|CDD|224117
NC_008312.1|WP_011610155.1|428292_429981_-|cytochrome-c-oxidase-subunit-I	unknown	unknown	gnl|CDD|213748
NC_008312.1|WP_011610167.1|446240_447479_+|serine-protease	unknown	unknown	gnl|CDD|379142
NC_008312.1|WP_011610159.1|433207_434281_-|alpha/beta-fold-hydrolase	unknown	unknown	gnl|CDD|223506
NC_008312.1|WP_011610156.1|430085_430994_-|cytochrome-c-oxidase-subunit-II	unknown	unknown	gnl|CDD|224537
NC_008312.1|WP_011610160.1|436167_437337_+|transaldolase	unknown	unknown	gnl|CDD|183426
NC_008312.1|WP_011610162.1|440974_442579_+|citramalate-synthase	unknown	unknown	gnl|CDD|237068
NC_008312.1|WP_011610164.1|443534_444284_+|class-I-SAM-dependent-methyltransferase	unknown	unknown	gnl|CDD|379312
NC_008312.1|WP_011610153.1|425177_426698_-|GMC-family-oxidoreductase	unknown	unknown	gnl|CDD|225186
NC_008312.1|WP_011610158.1|431614_432115_-|DUF2231-domain-containing-protein	unknown	unknown	gnl|CDD|226695
NC_008312.1|WP_011610169.1|449413_450586_-|pyridoxal-phosphate-dependent-aminotransferase	unknown	unknown	gnl|CDD|235596
NC_008312.1|WP_063823331.1|440382_440577_-|hypothetical-protein	unknown	unknown	unknown
NC_008312.1|WP_011610152.1|423918_424896_+|sulfotransferase-domain-containing-protein	unknown	unknown	gnl|CDD|366246
NC_008312.1|WP_011610157.1|431012_431618_-|DUF2231-domain-containing-protein	unknown	unknown	gnl|CDD|226695

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_008312.1|WP_011610171.1|452824_455425_+|M1-family-metallopeptidase	gnl|CDD|223385	COG0308, PepN, Aminopeptidase N [Amino acid transport and metabolism].	4.1231e-165
NC_008312.1|WP_011610161.1|438502_439606_-|glycine-oxidase-ThiO	gnl|CDD|274092	TIGR02352, Glycine_oxidase, glycine oxidase ThiO. This family consists of the homotetrameric, FAD-dependent glycine oxidase ThiO, from species such as Bacillus subtilis that use glycine in thiamine biosynthesis. In general, members of this family will not be found in species such as E. coli that instead use tyrosine and the ThiH protein. [Biosynthesis of cofactors, prosthetic groups, and carriers, Thiamine].	1.61678e-110
NC_008312.1|WP_011610154.1|427228_427843_-|heme-copper-oxidase-subunit-III	gnl|CDD|224758	COG1845, CyoC, Heme/copper-type cytochrome/quinol oxidase, subunit 3 [Energy production and conversion].	4.27283e-62
NC_008312.1|WP_011610151.1|422370_423588_+|MFS-transporter	gnl|CDD|341027	cd17474, MFS_YfmO_like, Bacillus subtilis multidrug efflux protein YfmO and similar transporters of the Major Facilitator Superfamily. This family is composed of Bacillus subtilis multidrug efflux protein YfmO, bacillibactin exporter YmfD/YmfE, uncharacterized MFS-type transporter YvmA, and similar proteins. YfmO acts to efflux copper or a copper complex, and could contribute to copper resistance. YmfD/YmfE is involved in secretion of bacillibactin. The YfmO-like family belongs to the Major Facilitator Superfamily (MFS) of membrane transport proteins, which are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	1.55816e-75
NC_008312.1|WP_011610168.1|447470_448331_-|hypothetical-protein	gnl|CDD|224117	COG1196, Smc, Chromosome segregation ATPases [Cell division and chromosome partitioning].	5.00943e-05
NC_008312.1|WP_011610155.1|428292_429981_-|cytochrome-c-oxidase-subunit-I	gnl|CDD|213748	TIGR02891, Probable_cytochrome_c_oxidase_subunit_1-beta, cytochrome c oxidase, subunit I. This large family represents subunit I's (CtaD, CoxA, CaaA) of cytochrome c oxidases of bacterial origin. Cytochrome c oxidase is the component of the respiratory chain that catalyzes the reduction of oxygen to water. Subunits I-III form the functional core of the enzyme complex. Subunit I is the catalytic subunit of the enzyme. Electrons originating in cytochrome c are transferred via the copper A center of subunit II and heme a of subunit I to the bimetallic center formed by heme a3 and copper B. This cytochrome c oxidase shows proton pump activity across the membrane in addition to the electron transfer. In the bacilli an apparent split (paralogism) has created a sister clade (TIGR02882) encoding subunits (QoxA) of the aa3-type quinone oxidase complex which reacts directly with quinones, bypassing the interaction with soluble cytochrome c. This model attempts to exclude these sequences, placing them between the trusted and noise cutoffs. These families, as well as archaeal and eukaryotic cytochrome c subunit I's are included within the superfamily model, pfam00115. [Energy metabolism, Electron transport].	0
NC_008312.1|WP_011610167.1|446240_447479_+|serine-protease	gnl|CDD|379142	pfam13365, Trypsin_2, Trypsin-like peptidase domain. This family includes trypsin-like peptidase domains.	1.08714e-25
NC_008312.1|WP_011610159.1|433207_434281_-|alpha/beta-fold-hydrolase	gnl|CDD|223506	COG0429, COG0429, Predicted hydrolase of the alpha/beta-hydrolase fold [General function prediction only].	2.76197e-88
NC_008312.1|WP_011610156.1|430085_430994_-|cytochrome-c-oxidase-subunit-II	gnl|CDD|224537	COG1622, CyoA, Heme/copper-type cytochrome/quinol oxidases, subunit 2 [Energy production and conversion].	6.47228e-62
NC_008312.1|WP_011610160.1|436167_437337_+|transaldolase	gnl|CDD|183426	PRK12309, PRK12309, transaldolase.	0
NC_008312.1|WP_011610162.1|440974_442579_+|citramalate-synthase	gnl|CDD|237068	PRK12344, PRK12344, putative alpha-isopropylmalate/homocitrate synthase family transferase; Provisional.	0
NC_008312.1|WP_011610164.1|443534_444284_+|class-I-SAM-dependent-methyltransferase	gnl|CDD|379312	pfam13649, Methyltransf_25, Methyltransferase domain. This family appears to be a methyltransferase domain.	7.37658e-11
NC_008312.1|WP_011610153.1|425177_426698_-|GMC-family-oxidoreductase	gnl|CDD|225186	COG2303, BetA, Choline dehydrogenase and related flavoproteins [Amino acid transport and metabolism].	1.27311e-76
NC_008312.1|WP_011610158.1|431614_432115_-|DUF2231-domain-containing-protein	gnl|CDD|226695	COG4244, COG4244, Predicted membrane protein [Function unknown].	1.4481e-50
NC_008312.1|WP_011610169.1|449413_450586_-|pyridoxal-phosphate-dependent-aminotransferase	gnl|CDD|235596	PRK05764, PRK05764, aspartate aminotransferase; Provisional.	0
NC_008312.1|WP_011610170.1|451429_452728_-|protein-glutamate-O-methyltransferase-family-protein	gnl|CDD|376673	pfam01937, DUF89, Protein of unknown function DUF89. This family has no known function.	7.6903e-79
NC_008312.1|WP_011610152.1|423918_424896_+|sulfotransferase-domain-containing-protein	gnl|CDD|366246	pfam00685, Sulfotransfer_1, Sulfotransferase domain.	1.78762e-32
NC_008312.1|WP_011610157.1|431012_431618_-|DUF2231-domain-containing-protein	gnl|CDD|226695	COG4244, COG4244, Predicted membrane protein [Function unknown].	4.98215e-36

Protein sequences

>NC_008312.1|WP_011610160.1|436167_437337_+|transaldolase
MAKNLLEQLRKVTIVVADTGDIQAIEKFQPRDATTNPSLITAAAQMPQYQEIVDETLKTARQELGTDATASDVANLAFKRLAVAFGLKILQIVPGRVSTEVDARLSYDTEATIAQGRDLIAQYEEAGVSRDRILIKIASTWEGIKAAEVLEKEGIHCNLTLLFGLHQAIACAEAGATLISPFVGRILDWYKKETGRDSYPPAEDPGVLSVTKVYNYYKKFGYKTEVMGASFRNTGEITELAGCDLLTISPGLLGELESTIGELPTKLSDEKAAQSDAEKILMDKETFDQMHAEDRMASQKLDEGIKGFSKALESLEKLLAERLTRLEGVTHAAEDIFYIYDLDGDGFITREEWAGSDAVFDALDINKDGKISPAEMASGLGAVFELAKV
>NC_008312.1|WP_011610159.1|433207_434281_-|alpha/beta-fold-hydrolase
MGNPSYSPPWFLKNGLAMTLYATFWIPRFWEETIKFSKLSYQDIIFIGANDVPIFGWMAIPENPKGTIIGTYGITGDLDNQWFLKLLGRKAYAQGYAVVLFDWRAHGKTALLSPTLTSDGIYEGQDFVHIAAQAKAMGCPPNFWFTGYSLGGQLTLWGAKVAESLAPELGLAETDIGGCAVICPSLEAQRSLSYLNSFPLGKRLDKGITKNLKKLAWLIHDYHPDFIDIEAIERANSIWKFDAEFIIKSLGFSSVEAYYKATSPLYFLPHLQKKTLIIYAEDDPLFDPTIVPELKTICQNNSAIDLILTRYGGHVAHISNKSCQKLAQDPDIWWAWNRVFEWIKQNETVTSRTEVAV
>NC_008312.1|WP_011610158.1|431614_432115_-|DUF2231-domain-containing-protein
MWEYLPPLNEHNLPYPDTIHPIVVHFVIAMVLFALLCDIIGYFTRNFRLYEVSWWNMFFATISIFIAIIFGQFEAGLAQPYEAVEPILNLHTLIGWSLSGIIAALTAWRYVIRSNNTEKLPMPYLGLGLVLVGIVCLQVYLGDELVWVYGLHTVPVVEAIKEGILQ
>NC_008312.1|WP_011610157.1|431012_431618_-|DUF2231-domain-containing-protein
MNLELIDSLTAQVGANGLPYAIPIHPNLVHLTLGLFIMGIAFDIVGILFPLQKPVLKVLAISATRSNFFDVGWYNMLASSIITFFTVAAGFYEIMLATPSPELKSVWGLGAMDTMLWHGIGGVLLLAMIIGMTIWRGFQRYIWSQDKLLQVQWSYLAVGLVILFVMYVHGTLGAQLAAEFGVHNTADALLELGKDPNIVLK
>NC_008312.1|WP_011610156.1|430085_430994_-|cytochrome-c-oxidase-subunit-II
MKTRTILTLGAIALLLAAISIWIGQLSYSWLPPQAAAESMLIDELFSFLVTLGSFIFLGVTGTIMYSILFQRAAKYDYSDGPHIEGNVTLEVVWTAIPIFLVFWIAAYSYNVYEKMAIQGPMELVHLHTPLEMESAYADPLEPVTEPVEEIQVYAKQWSWVFRYPENGVTSTELHLPVDRRVRVALNSEDVLHGFYIPAFRLKQDIIPNHPIDFEFTPVRVGKYSLTDSQYSGTYFATMAADVVVESAQDYKNWLAKVTDNKLSPAKNQAHTEYIQKLEAPVQPGWPSVRPASPPIVNYHNS
>NC_008312.1|WP_011610155.1|428292_429981_-|cytochrome-c-oxidase-subunit-I
MKEITIESISDAIEKPEPEQPPNWRRYFSFSTDHKVIGIQYLVTSFLFFLVGGIFAMVIRGELMTPESDLVDRTIYNGMFTMHGTVMLFLWTFPSLVGLANYLVPIMIGARDMAFPRLNAAAFWMVPVVGILMMASFFAPGGPAQAGWWSYPPVSIQNPTGSIITGQVIWILAVAISGVSSIMGAVNFVTTIVRMRSPGMTFFRMPAFVWTVFAAQIIQLFGLPALTAGAVMLLFDITVGTGFFNPANGGNPVLFQHFFWFYSHPAVYVIILPIFGIFSEVFPVYSRKPLFGYKVVVISSMIIAGVSGLVWVHHMYASGTPPWMRMVFMLSTMCVSVPTGIKVFAWVATIWGGKIRLNTPMLFSLGGLVMFVFAGITGIMLSSVPVDIHVNNTYFVVGHFHYVLYGTVTMGMYSAIYHWFPKMTGKMYYEGLGQLHFWLSFIGTNLNFLPMHPLGLQGMLRRVSSYAPQYELWNVLASLGAFLLGMSTLPFILNMVSSWIKGKKAPANPWRAIGLEWMISSPPDVENFEELPIIISEPYGYGKSEPLTANNPNGHTQLSVNG
>NC_008312.1|WP_011610154.1|427228_427843_-|heme-copper-oxidase-subunit-III
MNSAVTSEKVHGSLHSGVAEHHHDEEANSMFGFIVFLLSESVIFLSFFVGYIIYKTTMPDWLPPGISGLEVREPAINTVILVSSSFVIYFAEKALEKDNLTWFRIFLVATMAMGTYFVVGQGIEWSALEFGFTTGVFGGTFYLLTGFHGLHVITGILLQGIMLRRSFIPGNYDNSHFGINATSLFWHFVDVIWIILFILIYIWQ
>NC_008312.1|WP_011610153.1|425177_426698_-|GMC-family-oxidoreductase
MIIDDQHYDVIIVGTGAGGGTLAYKLAATGKKILILERGDFMPLEIQNRVNVDIFKKELYRAHENWYNDAGEAFSPQTNYAVGGNTKIYGAALIRMREKDFEAVEHQEGISPEWCLKYKDFEPYYTEAEQLYKVHGHSSNNSNEPHHSQEYPYPAVDHDPQIQTVVNAIAGQGLHPENIPLTLTREQEDPTGDSEVFGIAPLLNSPNITIKTNAKVVCLLTNSSGNTVKAVEVEIDERSFLFFGDIVVVACGAVNSAALLLRSANEKHPHGLANSSGQVGRNLMKHQMTAVVQPSPKPNSGNFLRSVCVNDFYWGDENYSYPMGHIQNTGGLLQDITFAESPPILSILAKAMPEVGLKRLALRSVGWWTYSEVLPDPNNRIEVKGDKLFFHYTPNNLEAHDRLVHRWIEVLKSVDKAVGNSFFARSGGNVYPRGEAPIEVVANQCGTCKFGEDPATSVLDINCRTHDVDNLYVVDSSFFPSSSAITPALTIIANALRVGEHLKERL
>NC_008312.1|WP_011610152.1|423918_424896_+|sulfotransferase-domain-containing-protein
MSINLSQTSEPKMNCIPRSFDVNAIENFYTTTFITKSGIENVFNHFVPRDSDIYVTTYPKSGTTWTMSILEHLVKKVSEKGISLGFSTEHFCPWLDRAASTENWRLIFSKFEKATSPRFFKSHASVGLIKQPARIIQCLRHPLDTFVSAWHHVRGKEEVFNYNGSWHHFFSKIALKGKFESSDWFDYHEEFLKASEEGKIEVLFLRYEEMKKDNAISAIHKLAEFIGVESYDAEEISRATNFTKMKEKSNQGHIEPDGSLSDMLVSQEVGDKNTPSKAHIRKGIVGDWKNYLSDSELNLWQNYVHIKKETCPRVIDFFSLEGLLC
>NC_008312.1|WP_011610151.1|422370_423588_+|MFS-transporter
MSKKTVSQNIKNSIKIYQDSNFQIIIGIISMAILGGPGISPLLPSIAKNWNISPEHIGWVISAFFIPITIGTPISGILADRYGRKQILIPALILFAISGTLCSLAPNFQTLIGLRFVQGIGAAPLESLTLTLISDFYSGKLLTTAMAFKTMSVGLSLVIYPLISSGLTTWGWRYPFLLYLIAIPLSIWILFSLKNPAIPKQKSFNLKKYLRNIWQSFNNYQVRSLLIVIIVNFIFSLGPCLTYIPLFADRQLGASYIVIGIILASRGIFLAFASSQLGIFAKYLSELTLIKISFIIYCIAFIMIPTINNIWLLFIPGILLGLAHGMLVPSTQSLLGQLSPENYRAGFMAVTSSALSFGRTLGPILAGSMFYIGGMAGVFYSSSIVSLVIFVFISYLVINTQSIKS
>NC_008312.1|WP_011610161.1|438502_439606_-|glycine-oxidase-ThiO
MSQSNKIIIIGGGIIGISIAIELKLRGAKVTVISRDFQQIATNAAAGMLAPQAEAIPPGKMLDLCLKSRTLYPEWVQKIESISGLETGYWSCGILSPVYALKDRENYALPSLNYQWLNQVAIHQYQPGLSPEVIGGWFYPQDGQVDNRYLYQSIIAAAKELKVEIQSGIVTEIIRKKGKIKSLKTSIGEIEAEHYVLATGAWSQELLPIPIFPTKGQMLSLKVPSYVSRENLSLQQVIYGSHCYIVPRKDGRIIIGATCENIGFVDGNTPVGIQQLLGNAIRLYPVLRDYEILEFWWGFRPNTPDEMPILGKSNYDNLTLATGHYRNGILLAPVTGMLIADLIWNNQSNSLLTAFNYSRFMEVGSQV
>NC_008312.1|WP_063823331.1|440382_440577_-|hypothetical-protein
MLIKNNVGVYNGNASIINFPSIGTCATCAMEIEEEVSQGKKFEKKLNFLRLPILLIIRKNYPFK
>NC_008312.1|WP_011610162.1|440974_442579_+|citramalate-synthase
MNKIWIYDTTLRDGAQREGLSLSLEDKLRIVHQLDSLGIPFIEGGWPGANPKDVQFFWHLKEQPLTQAEVVAFCSTRRPGKQAASDPTLQPILSAGTRWVTIFGKSWDLHVTEGLKTTLEENLEMISDTISYLCSQGCQVIYDAEHWFDGYKHNPNYALQTLTAAKNAGAQWLVLCDTNGGTLPHEATQIVADVSRELPNTRLGIHTHNDSGTAVANALSAVIEGVQMVQGTINGYGERCGNANLCTLIPNLQIKLGYDCIQSQKLEKLTQVSRGISEIVNLAPDDHAPFVGLSAFAHKGGIHVSAVERNPLTYEHIQPQEVGNTRRIVISDQAGLSNVLAKAKSFGIELDRQNPACRKILDKLKELENQGYQFEAAEASFELLMRSALERRQHFFEIKGFQVHLDKESAKVSNSLATVKVAVDGRDILEAAEGNGPVSALDTALRKALGNFYPAIANFYLTDYKVRILDSGAGTSAKTRVLIESSNGQQRWTTVGVSTNILDASYLAVIEGLEYGLMLESQSQENAVSVVIVN
>NC_008312.1|WP_044136274.1|442806_443052_-|hypothetical-protein
MLSANRIILDATAMINCGSLNEWEWLKRNYNFLYVAQEVLGSDNLELPTCQVARENFSSLSPNKEEMYVSFLEFINSKAMT
>NC_008312.1|WP_011610164.1|443534_444284_+|class-I-SAM-dependent-methyltransferase
MISNHSKNHYQNIANIYDNLWSYSPDYIKFTTQKIIQYLHLNATDTLVDIGCGTGIYSKEILHQIQLQQPIICVDNSAEMVGKIPANSRLNPIEMDGVKFSQKLGIYNKILLKEAIHHIKEKFILFQNLYQRLTPGGIFLLLLWPPTIEHPLFTEALESYEKKQPHYQEMINLLQQVGFVVDMDIIEYPLELPKSQYFEMVENCYMSLLSEFNDAELAEGLKEIEEKYQDKSVLKFSDRMVFIIATKSK
>NC_008312.1|WP_011610167.1|446240_447479_+|serine-protease
MILSRCNSFNTYFLGTATLGAIVITIPTAATAKTAQQVAEIAAPITVQINSNLGDGSGVIIAKNGNIYTVLTVNHVLEDSTIKYSVRTYQEKDYEVIDIVNLQITDEEPDLAILKFESSQTYPVATLGNSEQSVIGSQIYVFGYPATGGLFGTDRAPELSPGLVTSRPKSRPEGYTLRYQAVTWSGMSGGPVFDTNGRIIGIHGQGEFGFAQTNSGDVAPIKTGFNAAVPINSFMRKLSTAGIDRSDLIFDNTPVNTNPISTINPQSAEALYFRGISYLDQGDAWEAITNFNRALEKEPDSPEIYFNMGIARSLLVNPYEPITRGPNPIKDYTKAIELNPGYADAYYNRANAYYQNSLIYKSLKNKRKANQELLKAIKDLQKAGELYQEGGRIKAYKESLYLIKKLRNLLLV
>NC_008312.1|WP_011610168.1|447470_448331_-|hypothetical-protein
MLITLYLVTTIISCLAGLGFAYWLLEKRLTKQAQNYNGQLRAAHEQTYNVEQVWAQKIELLHTEHQGQIQQLKNKLEKKQAKIEALEVEHQKKLTDKIKLEHELQTQIKSLQAEQTQNLVFAESQAQETIRELTDKYSHQKIELERNYQQKIQENNSFWQLEYHKKFQELENIYQEKIQSINNFLQEKHQQEITKLENKHDQEIQKTIQSLEVKHKNKLRNQIRELEEMNQESILEIMRSITSQNQNQFQRKIQLLKQNYDTQLQLKIKSIKTEYQRQIRHLSKLD
>NC_008312.1|WP_011610169.1|449413_450586_-|pyridoxal-phosphate-dependent-aminotransferase
MKLAARVGKVPLSLTLAISAKARAMKADGKDVCSFSAGEPDFDTPEHIKVAAQKALDSGYTKYGPAAGEPKLREAIAHKLSQENGLNYKAENIIVTNGGKHSLFNLMLALIEPGDEVIIPAPYWLSYPEMVKLAGGEPIILTTDPETGYKVTPEQLRQSITDKTKLFVLNSPSNPTGMVYQPAEIKALAEVLVEKDILVVSDEIYEKIIYDDAEHLSIGAVNSEIFKNTIISNGFAKAYSMTGWRIGYLAAPVELINATVKIQGHSTSNVCTFAQYGAIAALESSQDCVEQMRQAFAKRRKIIYDLLKTLPGISCNQPEGAFYMFVNISKISSSSLEFCNALLEDQNVAVIPGIAFGADDHIRISYATDLETIEKGMDRLERFIRSQSSG
>NC_008312.1|WP_011610170.1|451429_452728_-|protein-glutamate-O-methyltransferase-family-protein
MNKFETSDFLLPLPVMPSEENTFAHYTIVCRLPGVIERVIKDNNFPPPIVQELEFLVTDLFEGWVRPLKDDQGPDLVAWESYLKPFEGKSWFDLPFYFAEAYFFRRLLEATNYFVPGIWQGIDPFGYQKRLSLEKSMDAIRFISDSVRVAQQYSLTTLSTIKSEQQTYQTFITTVLQAVLWGEQFDLTLWQAIAGDNTNRYLTQQQTHILVDDTYNLLNYLSNIQGQRIYLIITDNASFELVGDFFLIDFLLSTQTAHTVYLHLKAYPTFVSDAIHQDVFYTLERLANDTSENVRILAARLQEYIATGCLICQDNLFWNAPLAFWEMPESLREELAKASLVVIKGDANYRRILGDRHWLFTTPLSDIANYFPAPFVALRTLKSEVATSLEPDQIEILNEQDPLWLTNGQWGVIQFVIPEKLNNSGLTQIHYI
>NC_008312.1|WP_011610171.1|452824_455425_+|M1-family-metallopeptidase
MSSIYSEIENNSKSFELPGARPHYNPDRPGQVEHIFLNLELDIPNKSFQGICIISLNPIRSGIDKLTIDAVNLEIKSVKIENIEQTFDYDGKQLEIYLQVPTTVGQLVKVAITYSANNPQRGIYFIAPDEHYPDKPTQVWTQGEDEDSRFWFPCFDYPGQLSTSEIRVKVPNKFIAISNGELIHTEESEDNKIYHWIQKQVHPTYLMTLAVGKFAEIQDEWNGIPVTYYVEKKYQDHARRTMGKTPQMIEFFSQQFGYKYPYPKYAQVCVNDFIFGGMENTSTTLLTDRCLLDKKAALDNRSSESIVAHELAHQWFGDLIVIKHWSHAWIKEGMASYSEVLWTANEYGQDEAAYYLLKEARSYIVEDKGRYRRPIVTNIYREAIELYDRHLYEKGACVYHMIKTELGAELFTKAIHDFVQGNAHKTVETIDLLRAIEQTTGRNLLSLFDQYVFRGGHPDYKVNYAWDGNSKLAKITVTQILPKNDKNGDVSKGLFDLKIPIAFGYIQAEKPELINFTVRIHEQEQTFYFPLSEKPKFISFDVGNNYLKTVKLEYPLAELKAQLEFDPDPISRIYAAEALVKKGGLEVVKALSQALISEPFWGVRVEVAKQLGKIKLDQVFDGLAISLKDEDPRVRRAVVEALTQVKTHKSYKLLKYLVKNGDPSYYVEAIAVSGIGDIAAAHANSDEKPTEEKAIKLLKWVLQNKQGWNEVVRAGAISGLSKMKTSKTALNLILKYTVPGVPQGLRLNAIRVLGTISTAQPPVNLERILQRLTELSRETFFLTQVSVVAALSQMQTSRAIEILQNLANQTPDGRVRRRAEEAVQKVQKNIGSDKGIKQLRDELDKVKKENQELRSRLENLEAKAKV

Crispr_ID: NC_008312_3

• CRISPR_ID: NC_008312_3
• CRISPR_location: 612915-616884
• CRISPR_type: TypeV
• Repeat_type: NA
• Spacer_info: 63 spacers
• Cas_protein_info: cas14k

Consensus repeat of NC_008312_3

Consensus_repeat	Method
GGACCTACAGGACCTACNGGACCAG	CRT
GGACCTANAGGACCNNNNGGACCAG	CRT

spacers of NC_008312_3

>3.1|612940|38|NC_008312|CRT
TTGGACCTACAGGACCAGTGGCACCAATAGGACCAGCC
>3.2|613003|20|NC_008312|CRT
TAAAACCAGGAGCACCATCA
>3.3|613048|20|NC_008312|CRT
TGGCACCAATAGGACCAGCC
>3.4|613093|29|NC_008312|CRT
TAAAACCAGGAGCACCATCAGCTCCAGCC
>3.5|613147|20|NC_008312|CRT
GGGCACCACTTGGGCCTATA
>3.6|613192|20|NC_008312|CRT
CGGGACCAGGAGCTCCAGCA
>3.7|612958|65|NC_008312|CRT
TGGCACCAATAGGACCAGCCGGACCTACAGGACCTACAGGACCAGTAAAACCAGGAGCACCATCA
>3.8|613048|74|NC_008312|CRT
TGGCACCAATAGGACCAGCCGGACCTACAGGACCTACAGGACCAGTAAAACCAGGAGCACCATCAGCTCCAGCC
>3.9|613147|74|NC_008312|CRT
GGGCACCACTTGGGCCTATAGGACCTACAGGACCTATTGGACCAGCGGGACCAGGAGCTCCAGCAGGACCTACA
>3.10|613246|56|NC_008312|CRT
GAGCTCCAGCAGGACCAGCAAGACCAGGAACACCATCAGCTCCAGCCGGACCCACA
>3.11|613327|56|NC_008312|CRT
GAGCTCCAGTTGGACCTACAGGACCTACAGGACCTACAGGACCAGGGGCACCACTT
>3.12|613408|38|NC_008312|CRT
TAAGACCAGGAACACCATCAGCTCCAGCAGGACCTACA
>3.13|613471|56|NC_008312|CRT
GAGCTCCAGCAGGACCAGCAAGACCAGGAACACCATCAGCTCCAGCCGGACCCACA
>3.14|613552|56|NC_008312|CRT
GGGCACCACTTGGACCTATAGGACCAATGGGACCAGGAGCTCCAGTTGGACCTACA
>3.15|613633|38|NC_008312|CRT
CAAGACCAGGAATACCATCAGCTCCAGCCGGACCCACA
>3.16|613696|56|NC_008312|CRT
GGGCACCACTTGGACCTATAGGACCAATGGGACCAGGAGCTCCAGTTGGACCTACA
>3.17|613777|47|NC_008312|CRT
CAAGACCAGGAACACCATCAGCTCCAGCCGGACCTACAGGACCTATT
>3.18|613849|65|NC_008312|CRT
CAAGACCAGGAACACCATCAGCTCCAGCAGAACCTACAGGACCTACAGGACCTACAGGACCTATT
>3.19|613939|38|NC_008312|CRT
GAACACCATCAGCTCCAGCCGGACCCACAGGACCTATC
>3.20|614002|47|NC_008312|CRT
GAGCTCCAGCAGGACCAGCAAGACCAGGAACACCATCAGCTCCAGCG
>3.21|614074|20|NC_008312|CRT
CTGGACCAGGAGCTCCAGCA
>3.22|614119|29|NC_008312|CRT
CAAGACCAGGAACACCATCAGCTCCAGCC
>3.23|614173|20|NC_008312|CRT
CTGGACCAGGGGCTCCACTT
>3.24|614218|29|NC_008312|CRT
TAAGACCAGGAACACCATCAGCTCCAGCC
>3.25|614272|29|NC_008312|CRT
CCGGACCAGGGGCTCCAGTTAGACCTATA
>3.26|614326|20|NC_008312|CRT
CAGGACCAGGAGCACCAGTT
>3.27|614371|38|NC_008312|CRT
CAAGACCAGGAACACCATCAGCTCCAGCCGGACCCACA
>3.28|614434|20|NC_008312|CRT
CGGGACCAGGGGCACCACTT
>3.29|614479|29|NC_008312|CRT
TAAGACCAGGAACACCATCAGCTCCAGCT
>3.30|614533|38|NC_008312|CRT
CCGGACCAGCGGGACCAGGAGCTCCAGTAGGACCTACA
>3.31|614596|47|NC_008312|CRT
CAGGACCTACAGGACCAGCAAGACCAGGAACACCATCAGCTCCAGCC
>3.32|614668|20|NC_008312|CRT
CAGGACCAGGGGCACCACTT
>3.33|614713|29|NC_008312|CRT
TAAGACCAGGAACACCATCAGCTCCAGCC
>3.34|614767|38|NC_008312|CRT
CCGGACCAGCGGGACCAGGAGCTCCAGTAGGACCTACA
>3.35|614830|29|NC_008312|CRT
CAAGACCAGGAACACCATCAGCTCCAGCT
>3.36|614884|29|NC_008312|CRT
CCGGACCAGGGGCTCCAGTTAGACCTATA
>3.37|614938|20|NC_008312|CRT
CAGGACCAGGAGCACCAGTT
>3.38|614983|38|NC_008312|CRT
CAAGACCAGGAACACCATCAGCTCCAGCCGGACCCACA
>3.39|615046|20|NC_008312|CRT
CGGGACCAGGGGCACCACTT
>3.40|615091|29|NC_008312|CRT
TAAGACCAGGAACACCATCAGCTCCAGCT
>3.41|615145|47|NC_008312|CRT
CCGGACCAGCGGGACCAGGAGCTCCAGTAGGACCTACAGGACCTACA
>3.42|615217|38|NC_008312|CRT
CAAGACCAGGAACACCATCAGCTCCAGCCGGACCCACA
>3.43|615280|65|NC_008312|CRT
GGGCACCACTTGGACCTATAGGACCAATGGGACCAGTAAGACCAGGAACACCATCAGCTCCAGCC
>3.44|615370|38|NC_008312|CRT
CCGGACCAGCGGGACCAGGAGCTCCAGTAGGACCTACA
>3.45|615433|29|NC_008312|CRT
CAAGACCAGGAACACCATCAGCTCCAGCT
>3.46|615487|29|NC_008312|CRT
CCGGACCAGGGGCTCCAGTTAGACCTATA
>3.47|615541|20|NC_008312|CRT
CAGGACCAGGAGCACCAGTT
>3.48|615586|20|NC_008312|CRT
CAGGACCAGGGGCACCACTT
>3.49|615631|38|NC_008312|CRT
TAAGACCAGGAACACCATCAGCTCCAGCCGGACCTACA
>3.50|615694|56|NC_008312|CRT
GAGCTCCAGCAGGACCAGCAAGACCAGGAACACCATCAGCTCCAGCCGAACCTACA
>3.51|615775|74|NC_008312|CRT
GGGCACCACTTGGACCTATAGGACCAATGGGACCAGTAAGACCAGGAACACCATCAGATCCAGCCGGACCCACA
>3.52|615874|68|NC_008312|CRT
CGGGACCTACAGGACCTATTGGACCAGCGGGACCAGCGGGACCACCAGCGGGACCAGCGGGACCTACA
>3.53|615967|65|NC_008312|CRT
GAGCTCCAGTTGGACCCACAGGACCTATTGGACCAGCCGGACCAGGGGCTCCACTTGGACCTACA
>3.54|616057|56|NC_008312|CRT
GAACACCATCAGTTCCAGCCGGACCCACAGGACCTATTGGACCAGCGGGACCAGGA
>3.55|616138|74|NC_008312|CRT
GAACACCATCAGCTCCAGCCGGACCCACAGGACCTATTGGACCTACAGGACCAGGAGCTCCAGTTGGACCTACA
>3.56|616237|38|NC_008312|CRT
GAACACCATCAGCTCCAGCTGGACCTACAGGACCTATT
>3.57|616300|56|NC_008312|CRT
AAGCTCCAGCAGGACCAGCAAGACCAGGAACACCATCAGCTCCAGCCGGACCTACA
>3.58|616381|74|NC_008312|CRT
GGGCACCACTTGGACCTATAGGACCAATAGGACCAGTAAGACCAGGAACACCATCAGCTCCAGCCGAACCCACA
>3.59|616480|47|NC_008312|CRT
CGGGACCAGGAGCTCCAGTTGGACCTACAGGACCTACAGGACCAGCG
>3.60|616552|65|NC_008312|CRT
CAAGACCAGGAACACCATCAGCTCCAGCCGGACCCACAGGACCTATTGGACCTACAGGACCAGCG
>3.61|616642|83|NC_008312|CRT
CAGGACCTACAGGACCAGCAAGACCAGGAACACCATCAGCTCCAGCTGGACCTACAGGACCTATTGGACCTACAGGACCAGCG
>3.62|616750|47|NC_008312|CRT
CAGGACCTACAGGACCTATAGGACCTACAGGACCAGCAAGACCAGGA
>3.63|616822|38|NC_008312|CRT
CAGGACCTACAGGACCTACAGGACCAGCAAGGCCAGGA

CRISPR arrays and Neighbor proteins around NC_008312_3

CRISPR arrays

The CRISPR arrays of NC_008312_3

>merge|NC_008312|3|612915-616884|CRT,CRT
GGACCAGCTGGACCTACGGGACCAGTTGGACCTACAGGACCAGTGGCACCAATAGGACCAGCCGGACCTACAGGACCTACAGGACCAGTAAAACCAGGAGCACCATCAGCTCCAGCCGGACCTACAGGACCAGTGGCACCAATAGGACCAGCCGGACCTACAGGACCTACAGGACCAGTAAAACCAGGAGCACCATCAGCTCCAGCCGGACCTACAGGACCTACAGGACCAGGGGCACCACTTGGGCCTATAGGACCTACAGGACCTATTGGACCAGCGGGACCAGGAGCTCCAGCAGGACCTACAGGACCTATTGGACCAGCGGGACCAGGAGCTCCAGCAGGACCAGCAAGACCAGGAACACCATCAGCTCCAGCCGGACCCACAGGACCTATTGGACCTACAGGACCAGGAGCTCCAGTTGGACCTACAGGACCTACAGGACCTACAGGACCAGGGGCACCACTTGGACCTATAGGACCAATGGGACCAGTAAGACCAGGAACACCATCAGCTCCAGCAGGACCTACAGGACCTATTGGACCAGCGGGACCAGGAGCTCCAGCAGGACCAGCAAGACCAGGAACACCATCAGCTCCAGCCGGACCCACAGGACCTATTGGACCTACAGGACCAGGGGCACCACTTGGACCTATAGGACCAATGGGACCAGGAGCTCCAGTTGGACCTACAGGACCTACAGGACCTACAGGACCAGCAAGACCAGGAATACCATCAGCTCCAGCCGGACCCACAGGACCTATGGGACCTACAGGACCAGGGGCACCACTTGGACCTATAGGACCAATGGGACCAGGAGCTCCAGTTGGACCTACAGGACCTATTGGACCAGCAGGACCAGCAAGACCAGGAACACCATCAGCTCCAGCCGGACCTACAGGACCTATTGGACCTACAGGACCAGCAGGACCAGCAAGACCAGGAACACCATCAGCTCCAGCAGAACCTACAGGACCTACAGGACCTACAGGACCTATTGGACCTACAGGACCAGCAAGACCAGGAACACCATCAGCTCCAGCCGGACCCACAGGACCTATCGGACCTACAGGACCAGCGGGACCAGGAGCTCCAGCAGGACCAGCAAGACCAGGAACACCATCAGCTCCAGCGGGACCTACAGGACCTATTGGACCAGCTGGACCAGGAGCTCCAGCAGGACCTACAGGACCTACAGGACCAGCAAGACCAGGAACACCATCAGCTCCAGCCGGACCCACAGGACCTATTGGACCAGCTGGACCAGGGGCTCCACTTGGACCTATAGGACCAATGGGACCAGTAAGACCAGGAACACCATCAGCTCCAGCCGGACCCACAGGACCTATTGGACCAGCCGGACCAGGGGCTCCAGTTAGACCTATAGGACCTACAGGACCTACAGGACCCACAGGACCAGGAGCACCAGTTGGACCTACAGGACCTACAGGACCAGCAAGACCAGGAACACCATCAGCTCCAGCCGGACCCACAGGACCTATTGGACCTACAGGACCAGCGGGACCAGGGGCACCACTTGGACCTATAGGACCAATGGGACCAGTAAGACCAGGAACACCATCAGCTCCAGCTGGACCTACAGGACCTATTGGACCAGCCGGACCAGCGGGACCAGGAGCTCCAGTAGGACCTACAGGACCTACAGGACCTACAGGACCTACAGGACCTACAGGACCAGCAAGACCAGGAACACCATCAGCTCCAGCCGGACCCACAGGACCTATTGGACCTACAGGACCAGGGGCACCACTTGGACCTATAGGACCAATGGGACCAGTAAGACCAGGAACACCATCAGCTCCAGCCGGACCTACAGGACCTATTGGACCAGCCGGACCAGCGGGACCAGGAGCTCCAGTAGGACCTACAGGACCTACAGGACCTACAGGACCAGCAAGACCAGGAACACCATCAGCTCCAGCTGGACCTACAGGACCTATTGGACCAGCCGGACCAGGGGCTCCAGTTAGACCTATAGGACCTACAGGACCTACAGGACCCACAGGACCAGGAGCACCAGTTGGACCTACAGGACCTACAGGACCAGCAAGACCAGGAACACCATCAGCTCCAGCCGGACCCACAGGACCTATTGGACCTACAGGACCAGCGGGACCAGGGGCACCACTTGGACCTATAGGACCAATGGGACCAGTAAGACCAGGAACACCATCAGCTCCAGCTGGACCTACAGGACCTATTGGACCAGCCGGACCAGCGGGACCAGGAGCTCCAGTAGGACCTACAGGACCTACAGGACCTACAGGACCTACAGGACCAGCAAGACCAGGAACACCATCAGCTCCAGCCGGACCCACAGGACCTATTGGACCTACAGGACCAGGGGCACCACTTGGACCTATAGGACCAATGGGACCAGTAAGACCAGGAACACCATCAGCTCCAGCCGGACCTACAGGACCTATTGGACCAGCCGGACCAGCGGGACCAGGAGCTCCAGTAGGACCTACAGGACCTACAGGACCTACAGGACCAGCAAGACCAGGAACACCATCAGCTCCAGCTGGACCTACAGGGCCTATTGGACCAGCCGGACCAGGGGCTCCAGTTAGACCTATAGGACCTACAGGACCTACAGGACCCACAGGACCAGGAGCACCAGTTGGACCTACAGGACCTACAGGACCTACAGGACCAGGGGCACCACTTGGACCTATAGGACCAATGGGACCAGTAAGACCAGGAACACCATCAGCTCCAGCCGGACCTACAGGACCTATTGGACCAGCGGGACCAGGAGCTCCAGCAGGACCAGCAAGACCAGGAACACCATCAGCTCCAGCCGAACCTACAGGACCTATTGGACCTACAGGACCAGGGGCACCACTTGGACCTATAGGACCAATGGGACCAGTAAGACCAGGAACACCATCAGATCCAGCCGGACCCACAGGACCTATTGGACCAGCGGGACCAGCGGGACCTACAGGACCTATTGGACCAGCGGGACCAGCGGGACCACCAGCGGGACCAGCGGGACCTACAGGACCTATTGGACCAGCGGGACCAGGAGCTCCAGTTGGACCCACAGGACCTATTGGACCAGCCGGACCAGGGGCTCCACTTGGACCTACAGGACCTACAGGACCAGCAAGACCAGGAACACCATCAGTTCCAGCCGGACCCACAGGACCTATTGGACCAGCGGGACCAGGAGCTCCAGCAGGACCAGCAAGACCAGGAACACCATCAGCTCCAGCCGGACCCACAGGACCTATTGGACCTACAGGACCAGGAGCTCCAGTTGGACCTACAGGACCTACAGGACCAGCAAGACCAGGAACACCATCAGCTCCAGCTGGACCTACAGGACCTATTGGACCTACAGGACCAGCGGGACCAGAAGCTCCAGCAGGACCAGCAAGACCAGGAACACCATCAGCTCCAGCCGGACCTACAGGACCTATTGGACCAGCCGGACCAGGGGCACCACTTGGACCTATAGGACCAATAGGACCAGTAAGACCAGGAACACCATCAGCTCCAGCCGAACCCACAGGACCTATTGGACCAGCGGGACCAGCGGGACCAGGAGCTCCAGTTGGACCTACAGGACCTACAGGACCAGCGGGACCAGGAGCTCCAGCAGGACCAGCAAGACCAGGAACACCATCAGCTCCAGCCGGACCCACAGGACCTATTGGACCTACAGGACCAGCGGGACCAGGAGCTCCAGTTGGACCTACAGGACCTACAGGACCAGCAAGACCAGGAACACCATCAGCTCCAGCTGGACCTACAGGACCTATTGGACCTACAGGACCAGCGGGACCAGGAGCTCCAGTTGGACCTACAGGACCTACAGGACCTATAGGACCTACAGGACCAGCAAGACCAGGAACACCATCAGCTCCAGCCGGACCTACAGGACCTACAGGACCTACAGGACCAGCAAGGCCAGGAACACCATCAGCTCCAGCCGGACCCA

>NC_008312|3|1|612915-613236|CRT
GGACCAGCTGGACCTACGGGACCAG	TTGGACCTACAGGACCAGTGGCACCAATAGGACCAGCC
	TGGCACCAATAGGACCAGCCGGACCTACAGGACCTACAGGACCAGTAAAACCAGGAGCACCATCA
	TAAAACCAGGAGCACCATCA
GCTCCAGCCGGACCTACAGGACCAG	TGGCACCAATAGGACCAGCC
	TGGCACCAATAGGACCAGCCGGACCTACAGGACCTACAGGACCAGTAAAACCAGGAGCACCATCAGCTCCAGCC
	TAAAACCAGGAGCACCATCAGCTCCAGCC
GGACCTACAGGACCTACAGGACCAG	GGGCACCACTTGGGCCTATA
	GGGCACCACTTGGGCCTATAGGACCTACAGGACCTATTGGACCAGCGGGACCAGGAGCTCCAGCAGGACCTACA
	CGGGACCAGGAGCTCCAGCA
GGACCTACAGGACCTATTGGACCAGCGGGACCAG	GAGCTCCAGCAGGACCAGCAAGACCAGGAACACCATCAGCTCCAGCCGGACCCACA
GGACCTATTGGACCTACAGGACCAG	GAGCTCCAGTTGGACCTACAGGACCTACAGGACCTACAGGACCAGGGGCACCACTT
GGACCTATAGGACCAATGGGACCAG	TAAGACCAGGAACACCATCAGCTCCAGCAGGACCTACA
GGACCTATTGGACCAGCGGGACCAG	GAGCTCCAGCAGGACCAGCAAGACCAGGAACACCATCAGCTCCAGCCGGACCCACA
GGACCTATTGGACCTACAGGACCAG	GGGCACCACTTGGACCTATAGGACCAATGGGACCAGGAGCTCCAGTTGGACCTACA
GGACCTACAGGACCTACAGGACCAG	CAAGACCAGGAATACCATCAGCTCCAGCCGGACCCACA
GGACCTATGGGACCTACAGGACCAG	GGGCACCACTTGGACCTATAGGACCAATGGGACCAGGAGCTCCAGTTGGACCTACA
GGACCTATTGGACCAGCAGGACCAG	CAAGACCAGGAACACCATCAGCTCCAGCCGGACCTACAGGACCTATT
GGACCTACAGGACCAGCAGGACCAG	CAAGACCAGGAACACCATCAGCTCCAGCAGAACCTACAGGACCTACAGGACCTACAGGACCTATT
GGACCTACAGGACCAGCAAGACCAG	GAACACCATCAGCTCCAGCCGGACCCACAGGACCTATC
GGACCTACAGGACCAGCGGGACCAG	GAGCTCCAGCAGGACCAGCAAGACCAGGAACACCATCAGCTCCAGCG
GGACCTACAGGACCTATTGGACCAG	CTGGACCAGGAGCTCCAGCA
GGACCTACAGGACCTACAGGACCAG	CAAGACCAGGAACACCATCAGCTCCAGCC
GGACCCACAGGACCTATTGGACCAG	CTGGACCAGGGGCTCCACTT
GGACCTATAGGACCAATGGGACCAG	TAAGACCAGGAACACCATCAGCTCCAGCC
GGACCCACAGGACCTATTGGACCAG	CCGGACCAGGGGCTCCAGTTAGACCTATA
GGACCTACAGGACCTACAGGACCCA	CAGGACCAGGAGCACCAGTT
GGACCTACAGGACCTACAGGACCAG	CAAGACCAGGAACACCATCAGCTCCAGCCGGACCCACA
GGACCTATTGGACCTACAGGACCAG	CGGGACCAGGGGCACCACTT
GGACCTATAGGACCAATGGGACCAG	TAAGACCAGGAACACCATCAGCTCCAGCT
GGACCTACAGGACCTATTGGACCAG	CCGGACCAGCGGGACCAGGAGCTCCAGTAGGACCTACA
GGACCTACAGGACCTACAGGACCTA	CAGGACCTACAGGACCAGCAAGACCAGGAACACCATCAGCTCCAGCC
GGACCCACAGGACCTATTGGACCTA	CAGGACCAGGGGCACCACTT
GGACCTATAGGACCAATGGGACCAG	TAAGACCAGGAACACCATCAGCTCCAGCC
GGACCTACAGGACCTATTGGACCAG	CCGGACCAGCGGGACCAGGAGCTCCAGTAGGACCTACA
GGACCTACAGGACCTACAGGACCAG	CAAGACCAGGAACACCATCAGCTCCAGCT
GGACCTACAGGACCTATTGGACCAG	CCGGACCAGGGGCTCCAGTTAGACCTATA
GGACCTACAGGACCTACAGGACCCA	CAGGACCAGGAGCACCAGTT
GGACCTACAGGACCTACAGGACCAG	CAAGACCAGGAACACCATCAGCTCCAGCCGGACCCACA
GGACCTATTGGACCTACAGGACCAG	CGGGACCAGGGGCACCACTT
GGACCTATAGGACCAATGGGACCAG	TAAGACCAGGAACACCATCAGCTCCAGCT
GGACCTACAGGACCTATTGGACCAG	CCGGACCAGCGGGACCAGGAGCTCCAGTAGGACCTACAGGACCTACA
GGACCTACAGGACCTACAGGACCAG	CAAGACCAGGAACACCATCAGCTCCAGCCGGACCCACA
GGACCTATTGGACCTACAGGACCAG	GGGCACCACTTGGACCTATAGGACCAATGGGACCAGTAAGACCAGGAACACCATCAGCTCCAGCC
GGACCTACAGGACCTATTGGACCAG	CCGGACCAGCGGGACCAGGAGCTCCAGTAGGACCTACA
GGACCTACAGGACCTACAGGACCAG	CAAGACCAGGAACACCATCAGCTCCAGCT
GGACCTACAGGGCCTATTGGACCAG	CCGGACCAGGGGCTCCAGTTAGACCTATA
GGACCTACAGGACCTACAGGACCCA	CAGGACCAGGAGCACCAGTT
GGACCTACAGGACCTACAGGACCTA	CAGGACCAGGGGCACCACTT
GGACCTATAGGACCAATGGGACCAG	TAAGACCAGGAACACCATCAGCTCCAGCCGGACCTACA
GGACCTATTGGACCAGCGGGACCAG	GAGCTCCAGCAGGACCAGCAAGACCAGGAACACCATCAGCTCCAGCCGAACCTACA
GGACCTATTGGACCTACAGGACCAG	GGGCACCACTTGGACCTATAGGACCAATGGGACCAGTAAGACCAGGAACACCATCAGATCCAGCCGGACCCACA
GGACCTATTGGACCAGCGGGACCAG	CGGGACCTACAGGACCTATTGGACCAGCGGGACCAGCGGGACCACCAGCGGGACCAGCGGGACCTACA
GGACCTATTGGACCAGCGGGACCAG	GAGCTCCAGTTGGACCCACAGGACCTATTGGACCAGCCGGACCAGGGGCTCCACTTGGACCTACA
GGACCTACAGGACCAGCAAGACCAG	GAACACCATCAGTTCCAGCCGGACCCACAGGACCTATTGGACCAGCGGGACCAGGA
GCTCCAGCAGGACCAGCAAGACCAG	GAACACCATCAGCTCCAGCCGGACCCACAGGACCTATTGGACCTACAGGACCAGGAGCTCCAGTTGGACCTACA
GGACCTACAGGACCAGCAAGACCAG	GAACACCATCAGCTCCAGCTGGACCTACAGGACCTATT
GGACCTACAGGACCAGCGGGACCAG	AAGCTCCAGCAGGACCAGCAAGACCAGGAACACCATCAGCTCCAGCCGGACCTACA
GGACCTATTGGACCAGCCGGACCAG	GGGCACCACTTGGACCTATAGGACCAATAGGACCAGTAAGACCAGGAACACCATCAGCTCCAGCCGAACCCACA
GGACCTATTGGACCAGCGGGACCAG	CGGGACCAGGAGCTCCAGTTGGACCTACAGGACCTACAGGACCAGCG
GGACCAGGAGCTCCAGCAGGACCAG	CAAGACCAGGAACACCATCAGCTCCAGCCGGACCCACAGGACCTATTGGACCTACAGGACCAGCG
GGACCAGGAGCTCCAGTTGGACCTA	CAGGACCTACAGGACCAGCAAGACCAGGAACACCATCAGCTCCAGCTGGACCTACAGGACCTATTGGACCTACAGGACCAGCG
GGACCAGGAGCTCCAGTTGGACCTA	CAGGACCTACAGGACCTATAGGACCTACAGGACCAGCAAGACCAGGA
ACACCATCAGCTCCAGCCGGACCTA	CAGGACCTACAGGACCTACAGGACCAGCAAGGCCAGGA


>NC_008312|3|2|612933-616884|CRT
GGACCAG	TTGGACCTACAGGACCAGTGGCACCAATAGGACCAGCC
	TGGCACCAATAGGACCAGCCGGACCTACAGGACCTACAGGACCAGTAAAACCAGGAGCACCATCA
	TAAAACCAGGAGCACCATCA
GCTCCAGCCGGACCTACAGGACCAG	TGGCACCAATAGGACCAGCC
	TGGCACCAATAGGACCAGCCGGACCTACAGGACCTACAGGACCAGTAAAACCAGGAGCACCATCAGCTCCAGCC
	TAAAACCAGGAGCACCATCAGCTCCAGCC
GGACCTACAGGACCTACAGGACCAG	GGGCACCACTTGGGCCTATA
	GGGCACCACTTGGGCCTATAGGACCTACAGGACCTATTGGACCAGCGGGACCAGGAGCTCCAGCAGGACCTACA
	CGGGACCAGGAGCTCCAGCA
GGACCTACAGGACCTATTGGACCAGCGGGACCAG	GAGCTCCAGCAGGACCAGCAAGACCAGGAACACCATCAGCTCCAGCCGGACCCACA
GGACCTATTGGACCTACAGGACCAG	GAGCTCCAGTTGGACCTACAGGACCTACAGGACCTACAGGACCAGGGGCACCACTT
GGACCTATAGGACCAATGGGACCAG	TAAGACCAGGAACACCATCAGCTCCAGCAGGACCTACA
GGACCTATTGGACCAGCGGGACCAG	GAGCTCCAGCAGGACCAGCAAGACCAGGAACACCATCAGCTCCAGCCGGACCCACA
GGACCTATTGGACCTACAGGACCAG	GGGCACCACTTGGACCTATAGGACCAATGGGACCAGGAGCTCCAGTTGGACCTACA
GGACCTACAGGACCTACAGGACCAG	CAAGACCAGGAATACCATCAGCTCCAGCCGGACCCACA
GGACCTATGGGACCTACAGGACCAG	GGGCACCACTTGGACCTATAGGACCAATGGGACCAGGAGCTCCAGTTGGACCTACA
GGACCTATTGGACCAGCAGGACCAG	CAAGACCAGGAACACCATCAGCTCCAGCCGGACCTACAGGACCTATT
GGACCTACAGGACCAGCAGGACCAG	CAAGACCAGGAACACCATCAGCTCCAGCAGAACCTACAGGACCTACAGGACCTACAGGACCTATT
GGACCTACAGGACCAGCAAGACCAG	GAACACCATCAGCTCCAGCCGGACCCACAGGACCTATC
GGACCTACAGGACCAGCGGGACCAG	GAGCTCCAGCAGGACCAGCAAGACCAGGAACACCATCAGCTCCAGCG
GGACCTACAGGACCTATTGGACCAG	CTGGACCAGGAGCTCCAGCA
GGACCTACAGGACCTACAGGACCAG	CAAGACCAGGAACACCATCAGCTCCAGCC
GGACCCACAGGACCTATTGGACCAG	CTGGACCAGGGGCTCCACTT
GGACCTATAGGACCAATGGGACCAG	TAAGACCAGGAACACCATCAGCTCCAGCC
GGACCCACAGGACCTATTGGACCAG	CCGGACCAGGGGCTCCAGTTAGACCTATA
GGACCTACAGGACCTACAGGACCCA	CAGGACCAGGAGCACCAGTT
GGACCTACAGGACCTACAGGACCAG	CAAGACCAGGAACACCATCAGCTCCAGCCGGACCCACA
GGACCTATTGGACCTACAGGACCAG	CGGGACCAGGGGCACCACTT
GGACCTATAGGACCAATGGGACCAG	TAAGACCAGGAACACCATCAGCTCCAGCT
GGACCTACAGGACCTATTGGACCAG	CCGGACCAGCGGGACCAGGAGCTCCAGTAGGACCTACA
GGACCTACAGGACCTACAGGACCTA	CAGGACCTACAGGACCAGCAAGACCAGGAACACCATCAGCTCCAGCC
GGACCCACAGGACCTATTGGACCTA	CAGGACCAGGGGCACCACTT
GGACCTATAGGACCAATGGGACCAG	TAAGACCAGGAACACCATCAGCTCCAGCC
GGACCTACAGGACCTATTGGACCAG	CCGGACCAGCGGGACCAGGAGCTCCAGTAGGACCTACA
GGACCTACAGGACCTACAGGACCAG	CAAGACCAGGAACACCATCAGCTCCAGCT
GGACCTACAGGACCTATTGGACCAG	CCGGACCAGGGGCTCCAGTTAGACCTATA
GGACCTACAGGACCTACAGGACCCA	CAGGACCAGGAGCACCAGTT
GGACCTACAGGACCTACAGGACCAG	CAAGACCAGGAACACCATCAGCTCCAGCCGGACCCACA
GGACCTATTGGACCTACAGGACCAG	CGGGACCAGGGGCACCACTT
GGACCTATAGGACCAATGGGACCAG	TAAGACCAGGAACACCATCAGCTCCAGCT
GGACCTACAGGACCTATTGGACCAG	CCGGACCAGCGGGACCAGGAGCTCCAGTAGGACCTACAGGACCTACA
GGACCTACAGGACCTACAGGACCAG	CAAGACCAGGAACACCATCAGCTCCAGCCGGACCCACA
GGACCTATTGGACCTACAGGACCAG	GGGCACCACTTGGACCTATAGGACCAATGGGACCAGTAAGACCAGGAACACCATCAGCTCCAGCC
GGACCTACAGGACCTATTGGACCAG	CCGGACCAGCGGGACCAGGAGCTCCAGTAGGACCTACA
GGACCTACAGGACCTACAGGACCAG	CAAGACCAGGAACACCATCAGCTCCAGCT
GGACCTACAGGGCCTATTGGACCAG	CCGGACCAGGGGCTCCAGTTAGACCTATA
GGACCTACAGGACCTACAGGACCCA	CAGGACCAGGAGCACCAGTT
GGACCTACAGGACCTACAGGACCTA	CAGGACCAGGGGCACCACTT
GGACCTATAGGACCAATGGGACCAG	TAAGACCAGGAACACCATCAGCTCCAGCCGGACCTACA
GGACCTATTGGACCAGCGGGACCAG	GAGCTCCAGCAGGACCAGCAAGACCAGGAACACCATCAGCTCCAGCCGAACCTACA
GGACCTATTGGACCTACAGGACCAG	GGGCACCACTTGGACCTATAGGACCAATGGGACCAGTAAGACCAGGAACACCATCAGATCCAGCCGGACCCACA
GGACCTATTGGACCAGCGGGACCAG	CGGGACCTACAGGACCTATTGGACCAGCGGGACCAGCGGGACCACCAGCGGGACCAGCGGGACCTACA
GGACCTATTGGACCAGCGGGACCAG	GAGCTCCAGTTGGACCCACAGGACCTATTGGACCAGCCGGACCAGGGGCTCCACTTGGACCTACA
GGACCTACAGGACCAGCAAGACCAG	GAACACCATCAGTTCCAGCCGGACCCACAGGACCTATTGGACCAGCGGGACCAGGA
GCTCCAGCAGGACCAGCAAGACCAG	GAACACCATCAGCTCCAGCCGGACCCACAGGACCTATTGGACCTACAGGACCAGGAGCTCCAGTTGGACCTACA
GGACCTACAGGACCAGCAAGACCAG	GAACACCATCAGCTCCAGCTGGACCTACAGGACCTATT
GGACCTACAGGACCAGCGGGACCAG	AAGCTCCAGCAGGACCAGCAAGACCAGGAACACCATCAGCTCCAGCCGGACCTACA
GGACCTATTGGACCAGCCGGACCAG	GGGCACCACTTGGACCTATAGGACCAATAGGACCAGTAAGACCAGGAACACCATCAGCTCCAGCCGAACCCACA
GGACCTATTGGACCAGCGGGACCAG	CGGGACCAGGAGCTCCAGTTGGACCTACAGGACCTACAGGACCAGCG
GGACCAGGAGCTCCAGCAGGACCAG	CAAGACCAGGAACACCATCAGCTCCAGCCGGACCCACAGGACCTATTGGACCTACAGGACCAGCG
GGACCAGGAGCTCCAGTTGGACCTA	CAGGACCTACAGGACCAGCAAGACCAGGAACACCATCAGCTCCAGCTGGACCTACAGGACCTATTGGACCTACAGGACCAGCG
GGACCAGGAGCTCCAGTTGGACCTA	CAGGACCTACAGGACCTATAGGACCTACAGGACCAGCAAGACCAGGA
ACACCATCAGCTCCAGCCGGACCTA	CAGGACCTACAGGACCTACAGGACCAGCAAGGCCAGGA
ACACCATCAGCTCCAGCCGGACCCA

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_008312.1|WP_011610256.1|606873_607626_+|dienelactone-hydrolase-family-protein	unknown	unknown	gnl|CDD|223489
NC_008312.1|WP_011610265.1|631425_633651_+|FdhF/YdeP-family-oxidoreductase	unknown	unknown	gnl|CDD|239168
NC_008312.1|WP_011610253.1|603833_605684_+|hypothetical-protein	unknown	unknown	unknown
NC_008312.1|WP_155994233.1|620096_620255_+|hypothetical-protein	unknown	unknown	unknown
NC_008312.1|WP_155994237.1|633908_634079_-|hypothetical-protein	unknown	unknown	unknown
NC_008312.1|WP_011610263.1|627136_627862_+|pentapeptide-repeat-containing-protein	unknown	unknown	gnl|CDD|224276
NC_008312.1|WP_011610255.1|606397_606628_-|hypothetical-protein	unknown	unknown	gnl|CDD|273441
NC_008312.1|WP_011610266.1|634050_636180_-|calcium-binding-protein	unknown	unknown	gnl|CDD|225483
NC_008312.1|WP_011610261.1|622276_623410_+|glycosyltransferase-family-1-protein	unknown	unknown	gnl|CDD|340842
NC_008312.1|WP_155994231.1|605998_606166_-|hypothetical-protein	unknown	unknown	gnl|CDD|185702
NC_008312.1|WP_011610258.1|609070_609604_-|peptide-methionine-(S)-S-oxide-reductase-MsrA	unknown	unknown	gnl|CDD|376578
NC_008312.1|WP_155994229.1|603465_603630_-|hypothetical-protein	unknown	unknown	unknown
NC_008312.1|WP_044137112.1|599379_599778_+|hypothetical-protein	unknown	unknown	unknown
NC_008312.1|WP_011610249.1|597557_598646_+|sigma-70-family-RNA-polymerase-sigma-factor	unknown	unknown	gnl|CDD|274357
NC_008312.1|WP_155994235.1|630016_630193_+|hypothetical-protein	unknown	unknown	unknown
NC_008312.1|WP_011610262.1|623996_626591_+|adenylate/guanylate-cyclase-domain-containing-protein	unknown	unknown	gnl|CDD|143636
NC_008312.1|WP_011610260.1|620587_621844_+|NAD-dependent-epimerase/dehydratase-family-protein	unknown	unknown	gnl|CDD|215310
NC_008312.1|WP_081432380.1|608203_608632_+|IS200/IS605-family-element-transposase-accessory-protein-TnpB	cas14k	-	gnl|CDD|273793
NC_008312.1|WP_011610251.1|600304_603121_+|DUF4347-domain-containing-protein	unknown	unknown	gnl|CDD|372982
NC_008312.1|WP_011610264.1|628070_628838_+|type-I-methionyl-aminopeptidase	unknown	unknown	gnl|CDD|235576

HMMScan for Signature genes

Protein	Cas_name	Cas_description	E-value	Identity	Coverage
NC_008312.1|WP_081432380.1|608203_608632_+|IS200/IS605-family-element-transposase-accessory-protein-TnpB	cas14k	-	7e-14	45.8	5.1

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_008312.1|WP_011610256.1|606873_607626_+|dienelactone-hydrolase-family-protein	gnl|CDD|223489	COG0412, COG0412, Dienelactone hydrolase and related enzymes [Secondary metabolites biosynthesis, transport, and catabolism].	3.51537e-54
NC_008312.1|WP_011610265.1|631425_633651_+|FdhF/YdeP-family-oxidoreductase	gnl|CDD|239168	cd02767, MopB_ydeP, The MopB_ydeP CD includes a group of related uncharacterized bacterial molybdopterin-binding oxidoreductase-like domains with a putative molybdopterin cofactor binding site. These members belong to the molybdopterin_binding (MopB) superfamily of proteins.	0
NC_008312.1|WP_011610263.1|627136_627862_+|pentapeptide-repeat-containing-protein	gnl|CDD|224276	COG1357, COG1357, Pentapeptide repeats containing protein [Function unknown].	5.46185e-31
NC_008312.1|WP_011610255.1|606397_606628_-|hypothetical-protein	gnl|CDD|273441	TIGR01097, PhnE, phosphonate ABC transporter, permease protein PhnE. Phosphonates are a class of compound analogous to organic phosphates, but in which the C-O-P linkage is replaced by a direct, stable C-P bond. Some bacteria can utilize phosphonates as a source of phosphorus. This family consists of permease proteins of known or predicted phosphonate ABC transporters. Often this protein is found as a duplicated pair, occasionally as a fused pair. Certain "second" copies score in between the trusted and noise cutoff and should be considered true hits (by context). [Transport and binding proteins, Anions].	8.6059e-08
NC_008312.1|WP_011610266.1|634050_636180_-|calcium-binding-protein	gnl|CDD|225483	COG2931, COG2931, RTX toxins and related Ca2+-binding proteins [Secondary metabolites biosynthesis, transport, and catabolism].	2.24755e-24
NC_008312.1|WP_011610261.1|622276_623410_+|glycosyltransferase-family-1-protein	gnl|CDD|340842	cd03814, GT4-like, glycosyltransferase family 4 proteins. This family is most closely related to the GT4 family of glycosyltransferases and includes a sequence annotated as alpha-D-mannose-alpha(1-6)phosphatidyl myo-inositol monomannoside transferase from Bacillus halodurans. Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate residue. This group of glycosyltransferases is most closely related to the previously defined glycosyltransferase family 1 (GT1). The members of this family may transfer UDP, ADP, GDP, or CMP linked sugars. The diverse enzymatic activities among members of this family reflect a wide range of biological functions. The protein structure available for this family has the GTB topology, one of the two protein topologies observed for nucleotide-sugar-dependent glycosyltransferases. GTB proteins have distinct N- and C- terminal domains each containing a typical Rossmann fold. The two domains have high structural homology despite minimal sequence homology. The large cleft that separates the two domains includes the catalytic center and permits a high degree of flexibility. The members of this family are found mainly in bacteria and eukaryotes.	1.56901e-143
NC_008312.1|WP_155994231.1|605998_606166_-|hypothetical-protein	gnl|CDD|185702	cd09025, Aldose_epim_Slr1438, Aldose 1-epimerase, similar to Synechocystis Slr1438. Proteins similar to Synechocystis Slr1438 are uncharacterized members of aldose-1-epimerase superfamily. Aldose 1-epimerases or mutarotases are key enzymes of carbohydrate metabolism, catalyzing the interconversion of the alpha- and beta-anomers of hexose sugars such as glucose and galactose. This interconversion is an important step that allows anomer specific metabolic conversion of sugars. Studies of the catalytic mechanism of the best known member of the family, galactose mutarotase, have shown a glutamate and a histidine residue to be critical for catalysis; the glutamate serves as the active site base to initiate the reaction by removing the proton from the C-1 hydroxyl group of the sugar substrate, and the histidine as the active site acid to protonate the C-5 ring oxygen.	9.37834e-09
NC_008312.1|WP_011610258.1|609070_609604_-|peptide-methionine-(S)-S-oxide-reductase-MsrA	gnl|CDD|376578	pfam01625, PMSR, Peptide methionine sulfoxide reductase. This enzyme repairs damaged proteins. Methionine sulfoxide in proteins is reduced to methionine.	6.09054e-93
NC_008312.1|WP_011610249.1|597557_598646_+|sigma-70-family-RNA-polymerase-sigma-factor	gnl|CDD|274357	TIGR02937, RNA_polymerase_sigma_factor, RNA polymerase sigma factor, sigma-70 family. This model encompasses all varieties of the sigma-70 type sigma factors including the ECF subfamily. A number of sigma factors have names with a different number than 70 (i.e. sigma-38), but in fact, all except for the Sigma-54 family (TIGR02395) are included within this family. Several Pfam models hit segments of these sequences including Sigma-70 region 2 (pfam04542) and Sigma-70, region 4 (pfam04545), but not always above their respective trusted cutoffs.	3.02638e-20
NC_008312.1|WP_011610262.1|623996_626591_+|adenylate/guanylate-cyclase-domain-containing-protein	gnl|CDD|143636	cd07302, CHD, cyclase homology domain. Catalytic domains of the mononucleotidyl cyclases (MNC's), also called cyclase homology domains (CHDs), are part of the class III nucleotidyl cyclases. This class includes eukaryotic and prokaryotic adenylate cyclases (AC's) and guanylate cyclases (GC's). They seem to share a common catalytic mechanism in their requirement for two magnesium ions to bind the polyphosphate moiety of the nucleotide.	6.4757e-69
NC_008312.1|WP_011610260.1|620587_621844_+|NAD-dependent-epimerase/dehydratase-family-protein	gnl|CDD|215310	PLN02572, PLN02572, UDP-sulfoquinovose synthase.	0
NC_008312.1|WP_081432380.1|608203_608632_+|IS200/IS605-family-element-transposase-accessory-protein-TnpB	gnl|CDD|273793	TIGR01766, Putative_transposase_MJ0751, transposase, IS605 OrfB family, central region. This model represents a region of a sequence similarity between a family of putative transposases of Thermoanaerobacter tengcongensis, smaller related proteins from Bacillus anthracis, putative transposes described by pfam01385, and other proteins. [Mobile and extrachromosomal element functions, Transposon functions].	8.7574e-10
NC_008312.1|WP_011610251.1|600304_603121_+|DUF4347-domain-containing-protein	gnl|CDD|372982	pfam14252, DUF4347, Domain of unknown function (DUF4347). This domain family is found in bacteria and eukaryotes, and is approximately 160 amino acids in length. There are two completely conserved residues (C and G) that may be functionally important.	6.80464e-69
NC_008312.1|WP_011610264.1|628070_628838_+|type-I-methionyl-aminopeptidase	gnl|CDD|235576	PRK05716, PRK05716, methionine aminopeptidase; Validated.	1.2321e-162

Protein sequences

>NC_008312.1|WP_011610258.1|609070_609604_-|peptide-methionine-(S)-S-oxide-reductase-MsrA
MLDTIVLGGGCFWCVESVFLSVVGVKEVESGYAGGNTKNPDYRSICSGKTGHAEVVKVSFDTEKISLSQILEIFFATHDPTTPNRQGNDVGTQYRSVVMCHSQEQKDIAQEVISTLGNNGTFENPIVTEVVDLKDYYRAEEYHQNYFNKNPYQPYCVFSIPPKLQKLKKYFPDQVSA
>NC_008312.1|WP_081432380.1|608203_608632_+|IS200/IS605-family-element-transposase-accessory-protein-TnpB
MKHKGKAKYQSVLKDQKKTSHKIEGLTYHRNRFVENYLHNTSFLVVEYLSTNNIGTVVIGKNDNWKQDANIGKKKHQNFTQIPPYKLIQQITYKCQLAGIKVIETDIVTPVKLLHLTNSHQLNMKLMEVNESNVVYSGVQLV
>NC_008312.1|WP_011610256.1|606873_607626_+|dienelactone-hydrolase-family-protein
MQITKRNINLTVDDSLMRVYVATPKPPGTYPGIIFYSDIYQLGGPIIRLANYLAGYGYVVAAPEIFHRTESIGLVIEPDDLGRMRGNDNARRTAVSEYDADTQAVIEFLKAESSVAADQIGAMGFCIGGHLAFRAAFEKEIKATVCCYPTGIPSGKLGKGVADTIKRVSEIKGEILIVFGSKDPHTPESDRQTMIQTLEQTGVTHKIFLYEAEHTFMRDDGYRYDSVATTKAWSEITPFFNSVFKNNGNK
>NC_008312.1|WP_011610255.1|606397_606628_-|hypothetical-protein
MELATVGIYESLCSTRANLSQVVMFAVVPLILPEMVGYTLDIFAPNVRAASILGSEIDTGKRVNLIRTYTGTLYVA
>NC_008312.1|WP_155994231.1|605998_606166_-|hypothetical-protein
MGFYQTNFYQKTMPFSTGIHRYFAVNDKSKLEFYLPSNKYNFKEKKTVNTFFLRV
>NC_008312.1|WP_011610253.1|603833_605684_+|hypothetical-protein
MESLTRDNIYTVDQKASYLQLRSVSLDRKVTTRTIEPKSLTGLEISMSLTADCIFPDTPNDQKCSYTPSIITDRNSIDSDFLVPTRISQTSQAGEIVKPETLAFMERPGFQAGTSTQPIGLELYFPNAGAFPGNTQSQKTQIERKEENNYTAFTINSRIRQVVKANDTEAVLGRTIQGFVFFDDENQGLNTTIQGVAQFLPDIIPDLKGSENPVNSRINRHLFLAPNNTRLPGNSYTIYSAGVGRAKSLTPDITSLSQVPKGSYHSIWLGLSPIIDRSINQGRTFYDPTSPQVATTSSGSEGGEGSNVDFTSAINQDTFSTVSQDTFSTPNLRNFYVQVYLQFLEQDANLVQESIYQEKTSYYPHLSFAGNWTGPQDLFRYYTGAIASEKIKFYLGFDYTISTVNGWKFRTGGIGYINPDRDYYSQIFGNATKTFRISKNANFTLSTFFNYAIDRDTKIGSVVSNSPASALAARARLNWIKGSVGVTYYFGNVIPNSFENRLLLELSIRPLKTVTFGVTYSWAKVIPNSFEDRLLLKLSIRPLPTVTFSSFVAPIDKTSNSSPYGASVTWKLKNKYNSPTLSLNWQNQKHNYADDPFGNEIIVNDNNFTVMFRLSK
>NC_008312.1|WP_155994229.1|603465_603630_-|hypothetical-protein
MNFSFFFNEGGVGLASDANFFDGGLRSVAEVDHLGISANTGVKYAVVRIVEMIA
>NC_008312.1|WP_011610251.1|600304_603121_+|DUF4347-domain-containing-protein
MKLNTKSIVIIDASVENYQQLLNGVIPGVKPFLLGGDTDGIQQIGDILQKHPETDTLHIISHGSPGCLYLGNSQLSLDTLKGYEPQLQQWQLDNLLLYGCNVAAGDGGEEFIDKLHRLTGAEIAASKSLTGAAVKGGNWELEVRTGQTKPSLALQVEAMASYSDTLELQFEWAKHIGGQGLTYVYRITTDSIGNVLVAGVFDDNIDIDGDGNNDFTSNKDSSTRDAYVAKFDSNGNWIWAKQIGGRGSEDIKTITTDSSGNVLVAGGFGGNIDIDGDGNNDFSSNNDSSNNDAFAAKLDSNGNLVWAKQIGGSVTTGNYISGIITDSSGNALVAGTFKGNIDIDGDGNNDFTSNNDGSNDSYVAKFDSNGNLVWAKRIGGSNGNSSGAITIDSSDNVLVAGGFKGNIDIDDDGNNNFTSNGEADSYVAKFDSNGNFVWAKQFGSIRADYINSITTDSNGNVLVGGLFNSYIDIDGDGNNDFTSISDIDGYVAKLDSNGNLVWAKQFGSSLGGVVRSLTTDSSGNVLVVGNFSGDVDIDGDGNNDFTSNGNGNHTFTAKYDSNGNLVWVKHNLHNAYTITTDSSGNVLMVSDFNGNIDIDGDGDNDFTSNGDRNGLVVKFSDDTNSPPTDIALSNNTIDENVAANTPIGNLSSTDPDTGDTFTYSLVSGAGDTDNGTFNISGDELTIKSSPDYENKPSYSIRVETTDAAGETYQKELTINVNDLFDGNSGNDILRGTAAADSIYGLEGRDKLYGKGGNDIISGGADSDIVKGDSGDDQLNGDDGRDRLYGGTGNDIISGGEDKDIVKGDSGDDQLNGDAGPDRLYGGTGNDILLGGDGNDLLYGQGGDDELNGGPGMDRLYGSDGIDTFVLGEGQERDSIYNFAVGTDKIKLEGSLSFGQLQIFPRGSSSLIEVTATGEELAIVLGVNAADINDGSVFI
>NC_008312.1|WP_044137112.1|599379_599778_+|hypothetical-protein
MISRFVVVSGLVVCSALGLATVARAGEGGTAGSAAFTVDSDGKVTGVAVSAAVGKENASSAAFNYEAGSGVQNSAWSLGTAGTQEFTAVGDANGFNATSTEDSARGTDMTNTFSADPFSVNLGTTDGNSLVD
>NC_008312.1|WP_011610249.1|597557_598646_+|sigma-70-family-RNA-polymerase-sigma-factor
MLNEQKTTRNIDSLFWLEWQKHQEYLYRCCVKWMGGNSTNAEDALSMAMLKAREKIQQSSRRIENLKPWLAKLTYNLCMDLLKESARYNQGVEDLDLVISGADGSTQGGDPFFVVAYEELKDFCNLAIDDLPKRLRETFVLLYQKQFSSQEIAAELNISDSNVRKRISRGRAILEKRRQKEYEKQEEIVIVENQKIESSQPQELDTEIVTAEIPQETILSEEKSEPILVEATVEEELREIETFGNGGQQLFALSVLLKLLRVENKKPKGEKQQKCGLLSRCTNIGLALLRGRMNISGVRILLTQKYKKRLKWLTHKVIEAQPHYLYNFGKGELKALEKQLNWLIMENFLGPSAAKLVYKDCC
>NC_008312.1|WP_155994233.1|620096_620255_+|hypothetical-protein
MWKYGELKYQQLPSGTIIIDTSDVLDGISFPHDGLICQLKYKCELKLQGDHH
>NC_008312.1|WP_011610260.1|620587_621844_+|NAD-dependent-epimerase/dehydratase-family-protein
MKVLVIGGDGYCGWATALYLSNQGYEVGILDSMVRRHWDLQLQVETLTPIAPIQQRIQRWKDLTGKKIDLYIGDITNYDFLSTTLHQFEPESIVHFGEQRSAPFSMIDREHAVTTQVNNVVGTLNILYAMKEDFPDCHLVKLGTMGEYGTPNIDIEEGYIKIEHNGRTDTLPYPKQPGSFYHLSKVHDSHNIHFACKIWGIRATDLNQGIVYGVALTGLLNDETIQDELLINRLDYDGVFGTALNRFCIQAAIGHPLTVYGTGGQTRGFLDIRDTVRCMEIAIANPAQPGEFRVFNQFTEMFSVLDLAEMVKTAGKTMDLDVQINHLDNPRVELEQHYFNAKNTNLLELGLKPHYLSDSLLDSLLNFAIKYKTRVDKNHILPKVSWHREKTQQLDSVKSTLISKTEEKNKQSDSVKVQ
>NC_008312.1|WP_011610261.1|622276_623410_+|glycosyltransferase-family-1-protein
MKIALFTETFLPKIDGIVTRLCHTVENLQRFGDRVLIFSPAGGLKEYQGSPICGIEGFPLPLYPELKLAIPTPTIGEKLEQFQPDIIHVANPAVLGLGGLFYAKKLNIPLVASYHTHLPQYLHHYGLGMLEGLLWELLKSGHNQADLNLCTSTVMVEELRNHGIERVDLWQRGVDTELFQPHYANLEMRNYLSQGKPNNKIILYVGRLGVEKEIDRIKPIVEAIPNTCIAIVGDGPNRQNLEQYFANTPTHFVGYLRGQKLASAYASADAFIFPSRTETLGLVLLEAMAAGTPVVAANSGGIPDIVTNGINGYLFDPDDEKGAITATQKLFAHSEERETLRKNARAEAERWGWSAATQQLRNYYQKIISAHSIALAA
>NC_008312.1|WP_011610262.1|623996_626591_+|adenylate/guanylate-cyclase-domain-containing-protein
MKFSNPAGSILATLTQVERMGLLVTRVKDLPVEHFVCLLDFITAEFYQYLQAIDLINNEGIETVFEQLLNAFTLKIGQVLKADQTTIFLVNQEKKQLWYKKILESTGKSQEYHLPINVGILGHVATTGEALNIADAKSHPLFNEEVDQPQGYETRTILCIPIFSTINFLQPVAVVRLLNKVSDVPFDEEDEKLFRSFADSMGIILESCQSFYVAARNQQGVSALLNATTTLGQSLDLETTLRAVMDQARNLMQADRSTLFLLSKETNELWTKVATVDQTRMVEIRIPAHRGIAGYVASTGQTLNIPDAYLDPRFDPSTDKKTGYQTRNVLCMPVYNAKGELIGVTQLINKNQGSFTTSDEQFLLAFNAQAGIALQNSQLFENVLVEKQYQKDILRSLSDVVISTDMQGRIVTINEAALEMLGCPINQEVKGQTNRKVWEEKLIGRYLWEVIPIENLRFRLEDSLDHGTRQYVPEQNLRVGLFVEKQDQFESTYILAIPDNKNPNIYLAWGEKIATNIQTNLMDNNHKNLSKSIDSSKIDKVFERSLNLTINPLTNPEGGVRGGLVVLEDISQEKRMKNAMYRYMTPGVAEQVMALGEDALLEGERKEVTILFSDIRGYTTITENLEASEVVKLLNQYFETMVEAVFNHQGTLDKFIGDALMAVFGAPLSIEDHALMAVKTALDMRYRLREFNLSRPHETQFKIGVGISSGGVVSGNIGSQKRMDYTVIGDGVNLSSRLEAITKQYGCDIILSEFTYQLCSDYILVRELDKVRVKGKQKAVSIYELISASSEPITLETEKFLELYIKARQAYMKKKFSQALMYFELAQKIRPEDKAVAIHIERSLDYIKIPPPNDWDGIHTITTK
>NC_008312.1|WP_011610263.1|627136_627862_+|pentapeptide-repeat-containing-protein
MKLLILAIIIIVSQGGWINLAKAANPGAIRRLLETNECSGCDLTQANLSNANLIGADLEGANLRGANLSGANLGVTILSNANLSNANLSRAIMNDADLRGANLTDAYLSNANLSRAYLTKANLENANLFEANLIESLASGANLSNANLRHSYWFRANLENADLRESDLFNANMHQANLKNADFSNANLTTAKLMETNITLANLSGATLEGVNLRGTSIGSSVCLITNYIGCAPPKVIPEVK
>NC_008312.1|WP_011610264.1|628070_628838_+|type-I-methionyl-aminopeptidase
METETIVLLSKREIEKMRQAGRLAARLLNHLEPLVKPGVTTLELDEEAERWTQAHGARSAPLGYRGFPKSICTSINEVICHGIPSEKQVLKEGDIINIDVTPILDGYHGDTSKTFFVGTPSPLAKKLVEVTEKCMYLGIAEVKPGNKIGDIGAAIQEYAEAQGFSVVRDFVGHGVSKIFHTAPQIPHYGTRGKGKKLRAGMVFTIEPMINEGTWEGLVLEDGWTAITIDRKLSAQFEHTVAVTETGVEILTQYEG
>NC_008312.1|WP_155994235.1|630016_630193_+|hypothetical-protein
MMIKRGTKYCHLSELKVNIGETKRLLNYIFPMERLKKYIVREWELKQCLKTIKLVVTI
>NC_008312.1|WP_011610265.1|631425_633651_+|FdhF/YdeP-family-oxidoreductase
MLPKPNKIWNPKIWASWKPFGIGEQYPNNYWELIRAGIENIDQLPYAWNILNKGVCDGCSLGTTGMKDWTLDGFHLCNVRLRLLRLNTMPAFNPEILANISQLQNKSSGDLLQMGRLPYPMRRDKGDKGFRRISWDEAMAVISDRLKTTHPDRIGFYLTSRGTVNETYYATQKAARAIGTNNIDNAARICHSPSTGALKTTIGAAATTCSYKDWIGTDLLVFIGSNVANNQPVTVKYLHWAKKAGTKIVVINTYREPGMERYWVPSIPESALFGTKFAEDFFLVNVNGDMAFINGTIKHLIANDWIDKHFIDNYTNQFEELKASLDAQSWSELERFSGSTQDEMYAFAKMVGKAKKAVFVWSMGITQHECGEDNVRAIINLALTKGFVGREGCGLMPIRGHSGVQGGAEMGCYSTVFPGGRKINPENAEVMSKFWGFSVPNNPGLTTSEMIDNASEGKLDVLFSVGGNFLEVLPDPDYVKAAMKRVPLRVHQDIICSNQMLVEPGETVILLPTTTRYEIPGGVTETTTERRVIFSPEVPGQRIGEARPEWQVFMDLAKLVRPELADKLEFKNTGEIRQEIALVISQYSGIQHLKEPGDNFQYGGAHLCFGWNFPTPDKKAKFSILSPPKEELSKGYFLVATRRGKQFNSMVQSQKDAITGALREAILINPFDAQELGLKDGDNVRLKNDFGLFSGKVFLAPMKPGNLQVHWPEGNVLLDKGKRSVEGVPDYNALVCLEKLG
>NC_008312.1|WP_155994237.1|633908_634079_-|hypothetical-protein
MKETTFLLAKIVPSTMAKRSPFHKSILSNFIVEAIATPKIATLKSSRSKTQTYSHI
>NC_008312.1|WP_011610266.1|634050_636180_-|calcium-binding-protein
MAFYQGTNKKDNLKGTAKKDTINGKGGNDKIDGRGGNDKLNGGAGKDTLNGGAGKDTLNGGGGNDQINGGGSNDKLNGGAGKDTLNGSGGNDQINGGGSNDKLNGGAGKDTLNGGNAQDNLIGGSGNDFLDGGNGNDVLTGNDGNDVLVGNFGKDILTGGAGDDVFFLKQNSAVNNNSAADMITDFQPNFDTIGLDSGLTENDLNLQLSGNSTVIKIKKTGKILGVVQGVQPQELKWNFTSVDGKPNVIENLVTFDAPTVEQKSSDTYEMKLTGSDKSDFVINIKKTDTGTHQESLRYTPSPSEQRKGNKPFTAKVNSEGTRIELQFDDSPTVYIFDNQRDENTVDLIKKTATGETKIAEVPVDLEMKSNIEQSISQGTLCEAGQNICKSVEILDNVASGLAAVTALTGVGTVASGPLGAVALGAKVFGYGCLVLYGDDTDLVNNLIGEVAGNVFSQIGSKLFKAVASPTRKLVSKIIGNKYDQEIFKPLGDESFKQMEDFYLGKKGEELGKNTYDFIASILKTSEVITNKNQNSKSSDGLMQKIREGLGINWCNEKDEKDEKDEKKEVRVYFQPQGNPWAISKLYLVSPEEKFIGTAPNSFVSVNNDAFKWKSIGTFPIGTELEFETRVEGPLELSGSTNLVGGLTLSSKASEAASIKTNFLGMNLLGFEDGSSGKLLGVEVEKPNDFNDTLVKIENIIFEGNNIFVG

Crispr_ID: NC_008312_4

• CRISPR_ID: NC_008312_4
• CRISPR_location: 617166-617496
• CRISPR_type: TypeV
• Repeat_type: NA
• Spacer_info: 5 spacers
• Cas_protein_info: cas14k

Consensus repeat of NC_008312_4

Consensus_repeat	Method
GGACCTACAGGACCTANNGGACCNNCAGGACCAG	CRT

spacers of NC_008312_4

>4.1|617200|20|NC_008312|CRT
GAACACCATCAGCTCCAGCC
>4.2|617254|29|NC_008312|CRT
CAAGACCAGCGGGACCAGGAGCTCCAGTT
>4.3|617317|29|NC_008312|CRT
CAAGACCAGGAACACCATCAGCTCCAGCC
>4.4|617380|20|NC_008312|CRT
CGGGACCAGGAGCTCCAGTT
>4.5|617434|29|NC_008312|CRT
CAAGACCAGGAACACCATCAGCTCCAGCC

CRISPR arrays and Neighbor proteins around NC_008312_4

CRISPR arrays

The CRISPR arrays of NC_008312_4

>merge|NC_008312|4|617166-617496|CRT
GGACCTATAGGACCAATGGGACCAGTAAGACCAGGAACACCATCAGCTCCAGCCGGACCTACAGGACCTATTGGACCAGCTGGACCAGCAAGACCAGCGGGACCAGGAGCTCCAGTTGGACCTACAGGACCTACAGGACCTACAGGACCAGCAAGACCAGGAACACCATCAGCTCCAGCCGGACCTACAGGACCTACAGGACCTACAGGACCAGCGGGACCAGGAGCTCCAGTTGGACCTACAGGACCTACAGGACCTACAGGACCAGCAAGACCAGGAACACCATCAGCTCCAGCCGGACCTACAGGACCTATTGGACCTACAGGACCAG

>NC_008312|4|3|617166-617496|CRT
GGACCTATAGGACCAATGGGACCAGTAAGACCAG	GAACACCATCAGCTCCAGCC
GGACCTACAGGACCTATTGGACCAGCTGGACCAG	CAAGACCAGCGGGACCAGGAGCTCCAGTT
GGACCTACAGGACCTACAGGACCTACAGGACCAG	CAAGACCAGGAACACCATCAGCTCCAGCC
GGACCTACAGGACCTACAGGACCTACAGGACCAG	CGGGACCAGGAGCTCCAGTT
GGACCTACAGGACCTACAGGACCTACAGGACCAG	CAAGACCAGGAACACCATCAGCTCCAGCC
GGACCTACAGGACCTATTGGACCTACAGGACCAG

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_008312.1|WP_011610256.1|606873_607626_+|dienelactone-hydrolase-family-protein	unknown	unknown	gnl|CDD|223489
NC_008312.1|WP_011610265.1|631425_633651_+|FdhF/YdeP-family-oxidoreductase	unknown	unknown	gnl|CDD|239168
NC_008312.1|WP_011610253.1|603833_605684_+|hypothetical-protein	unknown	unknown	unknown
NC_008312.1|WP_155994233.1|620096_620255_+|hypothetical-protein	unknown	unknown	unknown
NC_008312.1|WP_155994237.1|633908_634079_-|hypothetical-protein	unknown	unknown	unknown
NC_008312.1|WP_011610263.1|627136_627862_+|pentapeptide-repeat-containing-protein	unknown	unknown	gnl|CDD|224276
NC_008312.1|WP_011610255.1|606397_606628_-|hypothetical-protein	unknown	unknown	gnl|CDD|273441
NC_008312.1|WP_011610266.1|634050_636180_-|calcium-binding-protein	unknown	unknown	gnl|CDD|225483
NC_008312.1|WP_011610261.1|622276_623410_+|glycosyltransferase-family-1-protein	unknown	unknown	gnl|CDD|340842
NC_008312.1|WP_155994231.1|605998_606166_-|hypothetical-protein	unknown	unknown	gnl|CDD|185702
NC_008312.1|WP_011610258.1|609070_609604_-|peptide-methionine-(S)-S-oxide-reductase-MsrA	unknown	unknown	gnl|CDD|376578
NC_008312.1|WP_155994229.1|603465_603630_-|hypothetical-protein	unknown	unknown	unknown
NC_008312.1|WP_044137112.1|599379_599778_+|hypothetical-protein	unknown	unknown	unknown
NC_008312.1|WP_011610249.1|597557_598646_+|sigma-70-family-RNA-polymerase-sigma-factor	unknown	unknown	gnl|CDD|274357
NC_008312.1|WP_155994235.1|630016_630193_+|hypothetical-protein	unknown	unknown	unknown
NC_008312.1|WP_011610262.1|623996_626591_+|adenylate/guanylate-cyclase-domain-containing-protein	unknown	unknown	gnl|CDD|143636
NC_008312.1|WP_011610260.1|620587_621844_+|NAD-dependent-epimerase/dehydratase-family-protein	unknown	unknown	gnl|CDD|215310
NC_008312.1|WP_081432380.1|608203_608632_+|IS200/IS605-family-element-transposase-accessory-protein-TnpB	cas14k	-	gnl|CDD|273793
NC_008312.1|WP_011610251.1|600304_603121_+|DUF4347-domain-containing-protein	unknown	unknown	gnl|CDD|372982
NC_008312.1|WP_011610264.1|628070_628838_+|type-I-methionyl-aminopeptidase	unknown	unknown	gnl|CDD|235576

HMMScan for Signature genes

Protein	Cas_name	Cas_description	E-value	Identity	Coverage
NC_008312.1|WP_081432380.1|608203_608632_+|IS200/IS605-family-element-transposase-accessory-protein-TnpB	cas14k	-	7e-14	45.8	5.1

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_008312.1|WP_011610256.1|606873_607626_+|dienelactone-hydrolase-family-protein	gnl|CDD|223489	COG0412, COG0412, Dienelactone hydrolase and related enzymes [Secondary metabolites biosynthesis, transport, and catabolism].	3.51537e-54
NC_008312.1|WP_011610265.1|631425_633651_+|FdhF/YdeP-family-oxidoreductase	gnl|CDD|239168	cd02767, MopB_ydeP, The MopB_ydeP CD includes a group of related uncharacterized bacterial molybdopterin-binding oxidoreductase-like domains with a putative molybdopterin cofactor binding site. These members belong to the molybdopterin_binding (MopB) superfamily of proteins.	0
NC_008312.1|WP_011610263.1|627136_627862_+|pentapeptide-repeat-containing-protein	gnl|CDD|224276	COG1357, COG1357, Pentapeptide repeats containing protein [Function unknown].	5.46185e-31
NC_008312.1|WP_011610255.1|606397_606628_-|hypothetical-protein	gnl|CDD|273441	TIGR01097, PhnE, phosphonate ABC transporter, permease protein PhnE. Phosphonates are a class of compound analogous to organic phosphates, but in which the C-O-P linkage is replaced by a direct, stable C-P bond. Some bacteria can utilize phosphonates as a source of phosphorus. This family consists of permease proteins of known or predicted phosphonate ABC transporters. Often this protein is found as a duplicated pair, occasionally as a fused pair. Certain "second" copies score in between the trusted and noise cutoff and should be considered true hits (by context). [Transport and binding proteins, Anions].	8.6059e-08
NC_008312.1|WP_011610266.1|634050_636180_-|calcium-binding-protein	gnl|CDD|225483	COG2931, COG2931, RTX toxins and related Ca2+-binding proteins [Secondary metabolites biosynthesis, transport, and catabolism].	2.24755e-24
NC_008312.1|WP_011610261.1|622276_623410_+|glycosyltransferase-family-1-protein	gnl|CDD|340842	cd03814, GT4-like, glycosyltransferase family 4 proteins. This family is most closely related to the GT4 family of glycosyltransferases and includes a sequence annotated as alpha-D-mannose-alpha(1-6)phosphatidyl myo-inositol monomannoside transferase from Bacillus halodurans. Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate residue. This group of glycosyltransferases is most closely related to the previously defined glycosyltransferase family 1 (GT1). The members of this family may transfer UDP, ADP, GDP, or CMP linked sugars. The diverse enzymatic activities among members of this family reflect a wide range of biological functions. The protein structure available for this family has the GTB topology, one of the two protein topologies observed for nucleotide-sugar-dependent glycosyltransferases. GTB proteins have distinct N- and C- terminal domains each containing a typical Rossmann fold. The two domains have high structural homology despite minimal sequence homology. The large cleft that separates the two domains includes the catalytic center and permits a high degree of flexibility. The members of this family are found mainly in bacteria and eukaryotes.	1.56901e-143
NC_008312.1|WP_155994231.1|605998_606166_-|hypothetical-protein	gnl|CDD|185702	cd09025, Aldose_epim_Slr1438, Aldose 1-epimerase, similar to Synechocystis Slr1438. Proteins similar to Synechocystis Slr1438 are uncharacterized members of aldose-1-epimerase superfamily. Aldose 1-epimerases or mutarotases are key enzymes of carbohydrate metabolism, catalyzing the interconversion of the alpha- and beta-anomers of hexose sugars such as glucose and galactose. This interconversion is an important step that allows anomer specific metabolic conversion of sugars. Studies of the catalytic mechanism of the best known member of the family, galactose mutarotase, have shown a glutamate and a histidine residue to be critical for catalysis; the glutamate serves as the active site base to initiate the reaction by removing the proton from the C-1 hydroxyl group of the sugar substrate, and the histidine as the active site acid to protonate the C-5 ring oxygen.	9.37834e-09
NC_008312.1|WP_011610258.1|609070_609604_-|peptide-methionine-(S)-S-oxide-reductase-MsrA	gnl|CDD|376578	pfam01625, PMSR, Peptide methionine sulfoxide reductase. This enzyme repairs damaged proteins. Methionine sulfoxide in proteins is reduced to methionine.	6.09054e-93
NC_008312.1|WP_011610249.1|597557_598646_+|sigma-70-family-RNA-polymerase-sigma-factor	gnl|CDD|274357	TIGR02937, RNA_polymerase_sigma_factor, RNA polymerase sigma factor, sigma-70 family. This model encompasses all varieties of the sigma-70 type sigma factors including the ECF subfamily. A number of sigma factors have names with a different number than 70 (i.e. sigma-38), but in fact, all except for the Sigma-54 family (TIGR02395) are included within this family. Several Pfam models hit segments of these sequences including Sigma-70 region 2 (pfam04542) and Sigma-70, region 4 (pfam04545), but not always above their respective trusted cutoffs.	3.02638e-20
NC_008312.1|WP_011610262.1|623996_626591_+|adenylate/guanylate-cyclase-domain-containing-protein	gnl|CDD|143636	cd07302, CHD, cyclase homology domain. Catalytic domains of the mononucleotidyl cyclases (MNC's), also called cyclase homology domains (CHDs), are part of the class III nucleotidyl cyclases. This class includes eukaryotic and prokaryotic adenylate cyclases (AC's) and guanylate cyclases (GC's). They seem to share a common catalytic mechanism in their requirement for two magnesium ions to bind the polyphosphate moiety of the nucleotide.	6.4757e-69
NC_008312.1|WP_011610260.1|620587_621844_+|NAD-dependent-epimerase/dehydratase-family-protein	gnl|CDD|215310	PLN02572, PLN02572, UDP-sulfoquinovose synthase.	0
NC_008312.1|WP_081432380.1|608203_608632_+|IS200/IS605-family-element-transposase-accessory-protein-TnpB	gnl|CDD|273793	TIGR01766, Putative_transposase_MJ0751, transposase, IS605 OrfB family, central region. This model represents a region of a sequence similarity between a family of putative transposases of Thermoanaerobacter tengcongensis, smaller related proteins from Bacillus anthracis, putative transposes described by pfam01385, and other proteins. [Mobile and extrachromosomal element functions, Transposon functions].	8.7574e-10
NC_008312.1|WP_011610251.1|600304_603121_+|DUF4347-domain-containing-protein	gnl|CDD|372982	pfam14252, DUF4347, Domain of unknown function (DUF4347). This domain family is found in bacteria and eukaryotes, and is approximately 160 amino acids in length. There are two completely conserved residues (C and G) that may be functionally important.	6.80464e-69
NC_008312.1|WP_011610264.1|628070_628838_+|type-I-methionyl-aminopeptidase	gnl|CDD|235576	PRK05716, PRK05716, methionine aminopeptidase; Validated.	1.2321e-162

Protein sequences

>NC_008312.1|WP_011610258.1|609070_609604_-|peptide-methionine-(S)-S-oxide-reductase-MsrA
MLDTIVLGGGCFWCVESVFLSVVGVKEVESGYAGGNTKNPDYRSICSGKTGHAEVVKVSFDTEKISLSQILEIFFATHDPTTPNRQGNDVGTQYRSVVMCHSQEQKDIAQEVISTLGNNGTFENPIVTEVVDLKDYYRAEEYHQNYFNKNPYQPYCVFSIPPKLQKLKKYFPDQVSA
>NC_008312.1|WP_081432380.1|608203_608632_+|IS200/IS605-family-element-transposase-accessory-protein-TnpB
MKHKGKAKYQSVLKDQKKTSHKIEGLTYHRNRFVENYLHNTSFLVVEYLSTNNIGTVVIGKNDNWKQDANIGKKKHQNFTQIPPYKLIQQITYKCQLAGIKVIETDIVTPVKLLHLTNSHQLNMKLMEVNESNVVYSGVQLV
>NC_008312.1|WP_011610256.1|606873_607626_+|dienelactone-hydrolase-family-protein
MQITKRNINLTVDDSLMRVYVATPKPPGTYPGIIFYSDIYQLGGPIIRLANYLAGYGYVVAAPEIFHRTESIGLVIEPDDLGRMRGNDNARRTAVSEYDADTQAVIEFLKAESSVAADQIGAMGFCIGGHLAFRAAFEKEIKATVCCYPTGIPSGKLGKGVADTIKRVSEIKGEILIVFGSKDPHTPESDRQTMIQTLEQTGVTHKIFLYEAEHTFMRDDGYRYDSVATTKAWSEITPFFNSVFKNNGNK
>NC_008312.1|WP_011610255.1|606397_606628_-|hypothetical-protein
MELATVGIYESLCSTRANLSQVVMFAVVPLILPEMVGYTLDIFAPNVRAASILGSEIDTGKRVNLIRTYTGTLYVA
>NC_008312.1|WP_155994231.1|605998_606166_-|hypothetical-protein
MGFYQTNFYQKTMPFSTGIHRYFAVNDKSKLEFYLPSNKYNFKEKKTVNTFFLRV
>NC_008312.1|WP_011610253.1|603833_605684_+|hypothetical-protein
MESLTRDNIYTVDQKASYLQLRSVSLDRKVTTRTIEPKSLTGLEISMSLTADCIFPDTPNDQKCSYTPSIITDRNSIDSDFLVPTRISQTSQAGEIVKPETLAFMERPGFQAGTSTQPIGLELYFPNAGAFPGNTQSQKTQIERKEENNYTAFTINSRIRQVVKANDTEAVLGRTIQGFVFFDDENQGLNTTIQGVAQFLPDIIPDLKGSENPVNSRINRHLFLAPNNTRLPGNSYTIYSAGVGRAKSLTPDITSLSQVPKGSYHSIWLGLSPIIDRSINQGRTFYDPTSPQVATTSSGSEGGEGSNVDFTSAINQDTFSTVSQDTFSTPNLRNFYVQVYLQFLEQDANLVQESIYQEKTSYYPHLSFAGNWTGPQDLFRYYTGAIASEKIKFYLGFDYTISTVNGWKFRTGGIGYINPDRDYYSQIFGNATKTFRISKNANFTLSTFFNYAIDRDTKIGSVVSNSPASALAARARLNWIKGSVGVTYYFGNVIPNSFENRLLLELSIRPLKTVTFGVTYSWAKVIPNSFEDRLLLKLSIRPLPTVTFSSFVAPIDKTSNSSPYGASVTWKLKNKYNSPTLSLNWQNQKHNYADDPFGNEIIVNDNNFTVMFRLSK
>NC_008312.1|WP_155994229.1|603465_603630_-|hypothetical-protein
MNFSFFFNEGGVGLASDANFFDGGLRSVAEVDHLGISANTGVKYAVVRIVEMIA
>NC_008312.1|WP_011610251.1|600304_603121_+|DUF4347-domain-containing-protein
MKLNTKSIVIIDASVENYQQLLNGVIPGVKPFLLGGDTDGIQQIGDILQKHPETDTLHIISHGSPGCLYLGNSQLSLDTLKGYEPQLQQWQLDNLLLYGCNVAAGDGGEEFIDKLHRLTGAEIAASKSLTGAAVKGGNWELEVRTGQTKPSLALQVEAMASYSDTLELQFEWAKHIGGQGLTYVYRITTDSIGNVLVAGVFDDNIDIDGDGNNDFTSNKDSSTRDAYVAKFDSNGNWIWAKQIGGRGSEDIKTITTDSSGNVLVAGGFGGNIDIDGDGNNDFSSNNDSSNNDAFAAKLDSNGNLVWAKQIGGSVTTGNYISGIITDSSGNALVAGTFKGNIDIDGDGNNDFTSNNDGSNDSYVAKFDSNGNLVWAKRIGGSNGNSSGAITIDSSDNVLVAGGFKGNIDIDDDGNNNFTSNGEADSYVAKFDSNGNFVWAKQFGSIRADYINSITTDSNGNVLVGGLFNSYIDIDGDGNNDFTSISDIDGYVAKLDSNGNLVWAKQFGSSLGGVVRSLTTDSSGNVLVVGNFSGDVDIDGDGNNDFTSNGNGNHTFTAKYDSNGNLVWVKHNLHNAYTITTDSSGNVLMVSDFNGNIDIDGDGDNDFTSNGDRNGLVVKFSDDTNSPPTDIALSNNTIDENVAANTPIGNLSSTDPDTGDTFTYSLVSGAGDTDNGTFNISGDELTIKSSPDYENKPSYSIRVETTDAAGETYQKELTINVNDLFDGNSGNDILRGTAAADSIYGLEGRDKLYGKGGNDIISGGADSDIVKGDSGDDQLNGDDGRDRLYGGTGNDIISGGEDKDIVKGDSGDDQLNGDAGPDRLYGGTGNDILLGGDGNDLLYGQGGDDELNGGPGMDRLYGSDGIDTFVLGEGQERDSIYNFAVGTDKIKLEGSLSFGQLQIFPRGSSSLIEVTATGEELAIVLGVNAADINDGSVFI
>NC_008312.1|WP_044137112.1|599379_599778_+|hypothetical-protein
MISRFVVVSGLVVCSALGLATVARAGEGGTAGSAAFTVDSDGKVTGVAVSAAVGKENASSAAFNYEAGSGVQNSAWSLGTAGTQEFTAVGDANGFNATSTEDSARGTDMTNTFSADPFSVNLGTTDGNSLVD
>NC_008312.1|WP_011610249.1|597557_598646_+|sigma-70-family-RNA-polymerase-sigma-factor
MLNEQKTTRNIDSLFWLEWQKHQEYLYRCCVKWMGGNSTNAEDALSMAMLKAREKIQQSSRRIENLKPWLAKLTYNLCMDLLKESARYNQGVEDLDLVISGADGSTQGGDPFFVVAYEELKDFCNLAIDDLPKRLRETFVLLYQKQFSSQEIAAELNISDSNVRKRISRGRAILEKRRQKEYEKQEEIVIVENQKIESSQPQELDTEIVTAEIPQETILSEEKSEPILVEATVEEELREIETFGNGGQQLFALSVLLKLLRVENKKPKGEKQQKCGLLSRCTNIGLALLRGRMNISGVRILLTQKYKKRLKWLTHKVIEAQPHYLYNFGKGELKALEKQLNWLIMENFLGPSAAKLVYKDCC
>NC_008312.1|WP_155994233.1|620096_620255_+|hypothetical-protein
MWKYGELKYQQLPSGTIIIDTSDVLDGISFPHDGLICQLKYKCELKLQGDHH
>NC_008312.1|WP_011610260.1|620587_621844_+|NAD-dependent-epimerase/dehydratase-family-protein
MKVLVIGGDGYCGWATALYLSNQGYEVGILDSMVRRHWDLQLQVETLTPIAPIQQRIQRWKDLTGKKIDLYIGDITNYDFLSTTLHQFEPESIVHFGEQRSAPFSMIDREHAVTTQVNNVVGTLNILYAMKEDFPDCHLVKLGTMGEYGTPNIDIEEGYIKIEHNGRTDTLPYPKQPGSFYHLSKVHDSHNIHFACKIWGIRATDLNQGIVYGVALTGLLNDETIQDELLINRLDYDGVFGTALNRFCIQAAIGHPLTVYGTGGQTRGFLDIRDTVRCMEIAIANPAQPGEFRVFNQFTEMFSVLDLAEMVKTAGKTMDLDVQINHLDNPRVELEQHYFNAKNTNLLELGLKPHYLSDSLLDSLLNFAIKYKTRVDKNHILPKVSWHREKTQQLDSVKSTLISKTEEKNKQSDSVKVQ
>NC_008312.1|WP_011610261.1|622276_623410_+|glycosyltransferase-family-1-protein
MKIALFTETFLPKIDGIVTRLCHTVENLQRFGDRVLIFSPAGGLKEYQGSPICGIEGFPLPLYPELKLAIPTPTIGEKLEQFQPDIIHVANPAVLGLGGLFYAKKLNIPLVASYHTHLPQYLHHYGLGMLEGLLWELLKSGHNQADLNLCTSTVMVEELRNHGIERVDLWQRGVDTELFQPHYANLEMRNYLSQGKPNNKIILYVGRLGVEKEIDRIKPIVEAIPNTCIAIVGDGPNRQNLEQYFANTPTHFVGYLRGQKLASAYASADAFIFPSRTETLGLVLLEAMAAGTPVVAANSGGIPDIVTNGINGYLFDPDDEKGAITATQKLFAHSEERETLRKNARAEAERWGWSAATQQLRNYYQKIISAHSIALAA
>NC_008312.1|WP_011610262.1|623996_626591_+|adenylate/guanylate-cyclase-domain-containing-protein
MKFSNPAGSILATLTQVERMGLLVTRVKDLPVEHFVCLLDFITAEFYQYLQAIDLINNEGIETVFEQLLNAFTLKIGQVLKADQTTIFLVNQEKKQLWYKKILESTGKSQEYHLPINVGILGHVATTGEALNIADAKSHPLFNEEVDQPQGYETRTILCIPIFSTINFLQPVAVVRLLNKVSDVPFDEEDEKLFRSFADSMGIILESCQSFYVAARNQQGVSALLNATTTLGQSLDLETTLRAVMDQARNLMQADRSTLFLLSKETNELWTKVATVDQTRMVEIRIPAHRGIAGYVASTGQTLNIPDAYLDPRFDPSTDKKTGYQTRNVLCMPVYNAKGELIGVTQLINKNQGSFTTSDEQFLLAFNAQAGIALQNSQLFENVLVEKQYQKDILRSLSDVVISTDMQGRIVTINEAALEMLGCPINQEVKGQTNRKVWEEKLIGRYLWEVIPIENLRFRLEDSLDHGTRQYVPEQNLRVGLFVEKQDQFESTYILAIPDNKNPNIYLAWGEKIATNIQTNLMDNNHKNLSKSIDSSKIDKVFERSLNLTINPLTNPEGGVRGGLVVLEDISQEKRMKNAMYRYMTPGVAEQVMALGEDALLEGERKEVTILFSDIRGYTTITENLEASEVVKLLNQYFETMVEAVFNHQGTLDKFIGDALMAVFGAPLSIEDHALMAVKTALDMRYRLREFNLSRPHETQFKIGVGISSGGVVSGNIGSQKRMDYTVIGDGVNLSSRLEAITKQYGCDIILSEFTYQLCSDYILVRELDKVRVKGKQKAVSIYELISASSEPITLETEKFLELYIKARQAYMKKKFSQALMYFELAQKIRPEDKAVAIHIERSLDYIKIPPPNDWDGIHTITTK
>NC_008312.1|WP_011610263.1|627136_627862_+|pentapeptide-repeat-containing-protein
MKLLILAIIIIVSQGGWINLAKAANPGAIRRLLETNECSGCDLTQANLSNANLIGADLEGANLRGANLSGANLGVTILSNANLSNANLSRAIMNDADLRGANLTDAYLSNANLSRAYLTKANLENANLFEANLIESLASGANLSNANLRHSYWFRANLENADLRESDLFNANMHQANLKNADFSNANLTTAKLMETNITLANLSGATLEGVNLRGTSIGSSVCLITNYIGCAPPKVIPEVK
>NC_008312.1|WP_011610264.1|628070_628838_+|type-I-methionyl-aminopeptidase
METETIVLLSKREIEKMRQAGRLAARLLNHLEPLVKPGVTTLELDEEAERWTQAHGARSAPLGYRGFPKSICTSINEVICHGIPSEKQVLKEGDIINIDVTPILDGYHGDTSKTFFVGTPSPLAKKLVEVTEKCMYLGIAEVKPGNKIGDIGAAIQEYAEAQGFSVVRDFVGHGVSKIFHTAPQIPHYGTRGKGKKLRAGMVFTIEPMINEGTWEGLVLEDGWTAITIDRKLSAQFEHTVAVTETGVEILTQYEG
>NC_008312.1|WP_155994235.1|630016_630193_+|hypothetical-protein
MMIKRGTKYCHLSELKVNIGETKRLLNYIFPMERLKKYIVREWELKQCLKTIKLVVTI
>NC_008312.1|WP_011610265.1|631425_633651_+|FdhF/YdeP-family-oxidoreductase
MLPKPNKIWNPKIWASWKPFGIGEQYPNNYWELIRAGIENIDQLPYAWNILNKGVCDGCSLGTTGMKDWTLDGFHLCNVRLRLLRLNTMPAFNPEILANISQLQNKSSGDLLQMGRLPYPMRRDKGDKGFRRISWDEAMAVISDRLKTTHPDRIGFYLTSRGTVNETYYATQKAARAIGTNNIDNAARICHSPSTGALKTTIGAAATTCSYKDWIGTDLLVFIGSNVANNQPVTVKYLHWAKKAGTKIVVINTYREPGMERYWVPSIPESALFGTKFAEDFFLVNVNGDMAFINGTIKHLIANDWIDKHFIDNYTNQFEELKASLDAQSWSELERFSGSTQDEMYAFAKMVGKAKKAVFVWSMGITQHECGEDNVRAIINLALTKGFVGREGCGLMPIRGHSGVQGGAEMGCYSTVFPGGRKINPENAEVMSKFWGFSVPNNPGLTTSEMIDNASEGKLDVLFSVGGNFLEVLPDPDYVKAAMKRVPLRVHQDIICSNQMLVEPGETVILLPTTTRYEIPGGVTETTTERRVIFSPEVPGQRIGEARPEWQVFMDLAKLVRPELADKLEFKNTGEIRQEIALVISQYSGIQHLKEPGDNFQYGGAHLCFGWNFPTPDKKAKFSILSPPKEELSKGYFLVATRRGKQFNSMVQSQKDAITGALREAILINPFDAQELGLKDGDNVRLKNDFGLFSGKVFLAPMKPGNLQVHWPEGNVLLDKGKRSVEGVPDYNALVCLEKLG
>NC_008312.1|WP_155994237.1|633908_634079_-|hypothetical-protein
MKETTFLLAKIVPSTMAKRSPFHKSILSNFIVEAIATPKIATLKSSRSKTQTYSHI
>NC_008312.1|WP_011610266.1|634050_636180_-|calcium-binding-protein
MAFYQGTNKKDNLKGTAKKDTINGKGGNDKIDGRGGNDKLNGGAGKDTLNGGAGKDTLNGGGGNDQINGGGSNDKLNGGAGKDTLNGSGGNDQINGGGSNDKLNGGAGKDTLNGGNAQDNLIGGSGNDFLDGGNGNDVLTGNDGNDVLVGNFGKDILTGGAGDDVFFLKQNSAVNNNSAADMITDFQPNFDTIGLDSGLTENDLNLQLSGNSTVIKIKKTGKILGVVQGVQPQELKWNFTSVDGKPNVIENLVTFDAPTVEQKSSDTYEMKLTGSDKSDFVINIKKTDTGTHQESLRYTPSPSEQRKGNKPFTAKVNSEGTRIELQFDDSPTVYIFDNQRDENTVDLIKKTATGETKIAEVPVDLEMKSNIEQSISQGTLCEAGQNICKSVEILDNVASGLAAVTALTGVGTVASGPLGAVALGAKVFGYGCLVLYGDDTDLVNNLIGEVAGNVFSQIGSKLFKAVASPTRKLVSKIIGNKYDQEIFKPLGDESFKQMEDFYLGKKGEELGKNTYDFIASILKTSEVITNKNQNSKSSDGLMQKIREGLGINWCNEKDEKDEKDEKKEVRVYFQPQGNPWAISKLYLVSPEEKFIGTAPNSFVSVNNDAFKWKSIGTFPIGTELEFETRVEGPLELSGSTNLVGGLTLSSKASEAASIKTNFLGMNLLGFEDGSSGKLLGVEVEKPNDFNDTLVKIENIIFEGNNIFVG

Crispr_ID: NC_008312_5

• CRISPR_ID: NC_008312_5
• CRISPR_location: 684856-684965
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers
• Cas_protein_info: RT

Consensus repeat of NC_008312_5

Consensus_repeat	Method
AAAATTGCCTGTAATAATCTCTTCAA	CRISPRCasFinder

spacers of NC_008312_5

>5.1|684882|58|NC_008312|CRISPRCasFinder
TATATAAGTAAAAATTTCACTAGCAATTAGTTGTTTTGCCTGTGGTAATAATAAAATT

CRISPR arrays and Neighbor proteins around NC_008312_5

CRISPR arrays

The CRISPR arrays of NC_008312_5

>merge|NC_008312|5|684856-684965|CRISPRCasFinder
AAAATTGCCTGTAATAATCTCTTCAATATATAAGTAAAAATTTCACTAGCAATTAGTTGTTTTGCCTGTGGTAATAATAAAATTAAAATTGCCTGTAATAATTTCTTCAA

>NC_008312|5|3|684856-684965|CRISPRCasFinder
AAAATTGCCTGTAATAATCTCTTCAA	TATATAAGTAAAAATTTCACTAGCAATTAGTTGTTTTGCCTGTGGTAATAATAAAATT
AAAATTGCCTGTAATAATTTCTTCAA

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_008312.1|WP_011610284.1|678195_678477_-|RP-ribonucleotide-reductase-like	unknown	unknown	gnl|CDD|153085
NC_008312.1|WP_011610288.1|682940_683198_-|hypothetical-protein	unknown	unknown	gnl|CDD|153085
NC_008312.1|WP_155994251.1|680661_680802_-|hypothetical-protein	unknown	unknown	unknown
NC_008312.1|WP_155994249.1|664959_665259_-|hypothetical-protein	unknown	unknown	gnl|CDD|226202
NC_008312.1|WP_011610278.1|663632_663986_+|glyoxalase/bleomycin-resistance/dioxygenase-family-protein	unknown	unknown	gnl|CDD|319925
NC_008312.1|WP_155994253.1|688949_690566_-|CocE/NonD-family-hydrolase	unknown	unknown	gnl|CDD|273375
NC_008312.1|WP_071820541.1|682571_682847_+|hypothetical-protein	unknown	unknown	unknown
NC_008312.1|WP_011610296.1|694773_695922_+|GTP-binding-protein	unknown	unknown	gnl|CDD|223597
NC_008312.1|WP_011610301.1|702712_703441_+|orotidine-5'-phosphate-decarboxylase	unknown	unknown	gnl|CDD|234695
NC_008312.1|WP_011610282.1|675848_677618_-|RNA-directed-DNA-polymerase	RT	pfam00078_RT_CAS-I:CAS-III	gnl|CDD|275209
NC_008312.1|WP_011610280.1|666286_669340_-|DUF4347-domain-containing-protein	unknown	unknown	gnl|CDD|372982
NC_008312.1|WP_155994635.1|698788_700603_-|PBP1A-family-penicillin-binding-protein	unknown	unknown	gnl|CDD|273955
NC_008312.1|WP_011610287.1|680791_682300_-|RNA-directed-DNA-polymerase	RT	pfam00078_RT_CAS-I:CAS-III	gnl|CDD|275209
NC_008312.1|WP_011610297.1|696401_696863_+|D-tyrosyl-tRNA(Tyr)-deacylase	unknown	unknown	gnl|CDD|235383
NC_008312.1|WP_011610277.1|659041_662110_+|DUF4347-domain-containing-protein	unknown	unknown	gnl|CDD|372982
NC_008312.1|WP_011610290.1|685182_685695_-|adenine-phosphoribosyltransferase	unknown	unknown	gnl|CDD|235028
NC_008312.1|WP_011610291.1|687516_688122_+|DUF3038-domain-containing-protein	unknown	unknown	gnl|CDD|371430
NC_008312.1|WP_011610295.1|692629_693079_-|cupin-domain-containing-protein	unknown	unknown	gnl|CDD|380392
NC_008312.1|WP_011610298.1|697750_698074_+|DUF1825-family-protein	unknown	unknown	gnl|CDD|370158
NC_008312.1|WP_155994636.1|700845_702060_+|tyrosine--tRNA-ligase	unknown	unknown	gnl|CDD|235645

HMMScan for Signature genes

Protein	Cas_name	Cas_description	E-value	Identity	Coverage
NC_008312.1|WP_011610282.1|675848_677618_-|RNA-directed-DNA-polymerase	RT	pfam00078_RT_CAS-I:CAS-III	4.3e-33	109.4	0.0
NC_008312.1|WP_011610287.1|680791_682300_-|RNA-directed-DNA-polymerase	RT	pfam00078_RT_CAS-I:CAS-III	6.8e-42	138.2	0.4

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_008312.1|WP_011610284.1|678195_678477_-|RP-ribonucleotide-reductase-like	gnl|CDD|153085	cd01676, RNR_II_monomer, Class II ribonucleotide reductase, monomeric form. Ribonucleotide reductase (RNR) catalyzes the reductive synthesis of deoxyribonucleotides from their corresponding ribonucleotides. It provides the precursors necessary for DNA synthesis. RNRs are separated into three classes based on their metallocofactor usage. Class I RNRs, found in eukaryotes, bacteria, and bacteriophage, use a diiron-tyrosyl radical. Class II RNRs, found in bacteria, bacteriophage, algae and archaea, use coenzyme B12 (adenosylcobalamin, AdoCbl). Class III RNRs, found in anaerobic bacteria, bacteriophage, and archaea, use an FeS cluster and S-adenosylmethionine to generate a glycyl radical. Many organisms have more than one class of RNR present in their genomes. All three RNRs have a ten-stranded alpha-beta barrel domain that is structurally similar to the domain of PFL (pyruvate formate lyase). Class II RNRs are found in bacteria that can live under both aerobic and anaerobic conditions. Many, but not all members of this class, are found to be homodimers. This particular subfamily is found to be active as a monomer. Adenosylcobalamin interacts directly with an active site cysteine to form the reactive cysteine radical.	1.00337e-19
NC_008312.1|WP_011610288.1|682940_683198_-|hypothetical-protein	gnl|CDD|153085	cd01676, RNR_II_monomer, Class II ribonucleotide reductase, monomeric form. Ribonucleotide reductase (RNR) catalyzes the reductive synthesis of deoxyribonucleotides from their corresponding ribonucleotides. It provides the precursors necessary for DNA synthesis. RNRs are separated into three classes based on their metallocofactor usage. Class I RNRs, found in eukaryotes, bacteria, and bacteriophage, use a diiron-tyrosyl radical. Class II RNRs, found in bacteria, bacteriophage, algae and archaea, use coenzyme B12 (adenosylcobalamin, AdoCbl). Class III RNRs, found in anaerobic bacteria, bacteriophage, and archaea, use an FeS cluster and S-adenosylmethionine to generate a glycyl radical. Many organisms have more than one class of RNR present in their genomes. All three RNRs have a ten-stranded alpha-beta barrel domain that is structurally similar to the domain of PFL (pyruvate formate lyase). Class II RNRs are found in bacteria that can live under both aerobic and anaerobic conditions. Many, but not all members of this class, are found to be homodimers. This particular subfamily is found to be active as a monomer. Adenosylcobalamin interacts directly with an active site cysteine to form the reactive cysteine radical.	5.87146e-18
NC_008312.1|WP_155994249.1|664959_665259_-|hypothetical-protein	gnl|CDD|226202	COG3677, COG3677, Transposase and inactivated derivatives [DNA replication, recombination, and repair].	0.00160048
NC_008312.1|WP_011610278.1|663632_663986_+|glyoxalase/bleomycin-resistance/dioxygenase-family-protein	gnl|CDD|319925	cd07264, VOC_like, uncharacterized subfamily of vicinal oxygen chelate (VOC) family. The vicinal oxygen chelate (VOC) superfamily is composed of structurally related proteins with paired beta.alpha.beta.beta.beta motifs that provide a metal coordination environment with two or three open or readily accessible coordination sites to promote direct electrophilic participation of the metal ion in catalysis. VOC domain is found in a variety of structurally related metalloproteins, including the bleomycin resistance protein, glyoxalase I, and type I ring-cleaving dioxygenases. A bound metal ion is required for protein activities for the members of this superfamily. A variety of metal ions have been found in the catalytic centers of these proteins including Fe(II), Mn(II), Zn(II), Ni(II) and Mg(II). The protein superfamily contains members with or without domain swapping. The proteins of this family share three conserved metal binding amino acids with the type I extradiol dioxygenases, which shows no domain swapping.	6.83197e-16
NC_008312.1|WP_155994253.1|688949_690566_-|CocE/NonD-family-hydrolase	gnl|CDD|273375	TIGR00976, Hypothetical_protein_Rv1835c/MT1883/Mb1866c., putative hydrolase, CocE/NonD family. This model represents a protein subfamily that includes the cocaine esterase CocE, several glutaryl-7-ACA acylases, and the putative diester hydrolase NonD of Streptomyces griseus (all hydrolases). This family shows extensive, low-level similarity to a family of xaa-pro dipeptidyl-peptidases, and local similarity by PSI-BLAST to many other hydrolases. [Unknown function, Enzymes of unknown specificity].	1.75292e-144
NC_008312.1|WP_011610297.1|696401_696863_+|D-tyrosyl-tRNA(Tyr)-deacylase	gnl|CDD|235383	PRK05273, PRK05273, D-tyrosyl-tRNA(Tyr) deacylase; Provisional.	8.98707e-87
NC_008312.1|WP_011610296.1|694773_695922_+|GTP-binding-protein	gnl|CDD|223597	COG0523, COG0523, Putative GTPases (G3E family) [General function prediction only].	3.88532e-106
NC_008312.1|WP_011610301.1|702712_703441_+|orotidine-5'-phosphate-decarboxylase	gnl|CDD|234695	PRK00230, PRK00230, orotidine-5'-phosphate decarboxylase.	1.38084e-124
NC_008312.1|WP_011610282.1|675848_677618_-|RNA-directed-DNA-polymerase	gnl|CDD|275209	TIGR04416, hypothetical_protein, group II intron reverse transcriptase/maturase. Members of this protein family are multifunctional proteins encoded in most examples of bacterial group II introns. These group II introns are mobile selfish genetic elements, often with multiple highly identical copies per genome. Member proteins have an N-terminal reverse transcriptase (RNA-directed DNA polymerase) domain (pfam00078) followed by an RNA-binding maturase domain (pfam08388). Some members of this family may have an additional C-terminal DNA endonuclease domain that this model does not cover. A region of the group II intron ribozyme structure should be detectable nearby on the genome by Rfam model RF00029. [Mobile and extrachromosomal element functions, Other].	7.30232e-94
NC_008312.1|WP_011610280.1|666286_669340_-|DUF4347-domain-containing-protein	gnl|CDD|372982	pfam14252, DUF4347, Domain of unknown function (DUF4347). This domain family is found in bacteria and eukaryotes, and is approximately 160 amino acids in length. There are two completely conserved residues (C and G) that may be functionally important.	1.58421e-57
NC_008312.1|WP_155994635.1|698788_700603_-|PBP1A-family-penicillin-binding-protein	gnl|CDD|273955	TIGR02074, Includes:_Penicillin-insensitive_transglycosylase, penicillin-binding protein, 1A family. Bacterial that synthesize a cell wall of peptidoglycan (murein) generally have several transglycosylases and transpeptidases for the task. This family consists of bifunctional transglycosylase/transpeptidase penicillin-binding proteins (PBP). In the Proteobacteria, this family includes PBP 1A but not the paralogous PBP 1B (TIGR02071). This family also includes related proteins, often designated PBP 1A, from other bacterial lineages. [Cell envelope, Biosynthesis and degradation of murein sacculus and peptidoglycan].	0
NC_008312.1|WP_011610287.1|680791_682300_-|RNA-directed-DNA-polymerase	gnl|CDD|275209	TIGR04416, hypothetical_protein, group II intron reverse transcriptase/maturase. Members of this protein family are multifunctional proteins encoded in most examples of bacterial group II introns. These group II introns are mobile selfish genetic elements, often with multiple highly identical copies per genome. Member proteins have an N-terminal reverse transcriptase (RNA-directed DNA polymerase) domain (pfam00078) followed by an RNA-binding maturase domain (pfam08388). Some members of this family may have an additional C-terminal DNA endonuclease domain that this model does not cover. A region of the group II intron ribozyme structure should be detectable nearby on the genome by Rfam model RF00029. [Mobile and extrachromosomal element functions, Other].	4.58094e-96
NC_008312.1|WP_011610277.1|659041_662110_+|DUF4347-domain-containing-protein	gnl|CDD|372982	pfam14252, DUF4347, Domain of unknown function (DUF4347). This domain family is found in bacteria and eukaryotes, and is approximately 160 amino acids in length. There are two completely conserved residues (C and G) that may be functionally important.	2.16557e-57
NC_008312.1|WP_011610290.1|685182_685695_-|adenine-phosphoribosyltransferase	gnl|CDD|235028	PRK02304, PRK02304, adenine phosphoribosyltransferase; Provisional.	2.63681e-96
NC_008312.1|WP_011610291.1|687516_688122_+|DUF3038-domain-containing-protein	gnl|CDD|371430	pfam11237, DUF3038, Protein of unknown function (DUF3038). This family of proteins with unknown function appear to be restricted to Cyanobacteria.	2.37293e-84
NC_008312.1|WP_011610295.1|692629_693079_-|cupin-domain-containing-protein	gnl|CDD|380392	cd06987, cupin_MAE_RS03005, Microcystis aeruginosa MAE_RS03005 and related proteins, cupin domain. This family includes bacterial and some eukaryotic proteins homologous to MAE_RS03005, a Microcystis aeruginosa protein of unknown function. Proteins in this family belong to the cupin superfamily with a conserved "jelly roll-like" beta-barrel fold capable of homodimerization.	1.01666e-68
NC_008312.1|WP_011610298.1|697750_698074_+|DUF1825-family-protein	gnl|CDD|370158	pfam08855, DUF1825, Domain of unknown function (DUF1825). This uncharacterized family of proteins are principally found in cyanobacteria.	7.34924e-47
NC_008312.1|WP_155994636.1|700845_702060_+|tyrosine--tRNA-ligase	gnl|CDD|235645	PRK05912, PRK05912, tyrosyl-tRNA synthetase; Validated.	0

Protein sequences

>NC_008312.1|WP_011610288.1|682940_683198_-|hypothetical-protein
MVQEVEKIRQREFPEAAPTANPVFYRTYSRKTKTGRETWVEVCDRTIDGLRKLGQLTEEETDLLYRMQSQLKALSSGRWLWVGGV
>NC_008312.1|WP_071820541.1|682571_682847_+|hypothetical-protein
MSFDCSVSTILFATYWVTTVQTYLHFRYPCVLACWDLPYGSVLPAFIPALSFDNQSLDRGNAFTPTLWRVGLSPTRLYSSQGSMVCRFVKR
>NC_008312.1|WP_011610287.1|680791_682300_-|RNA-directed-DNA-polymerase
MTKTRKNPMVVWTPVNWRKLKRVVYKLQKRIYQAAQRGDVKAVRKLQKTLLNSWSAKMLATRRVIQDNKGQKTAGIDGKKSLTLKERVNLANNLVMSHKAKSTCRIWIPKPGKTEKRPLGILTISERAKQGLVKMAIEPEWEAKFEPNIYGFRPGRSCMDAVEGIKAAIKQKSKYVLNADIAKCFDNIDHEKLLDKIGTFPKVRRQIKAWLKSGVYDNESWFLMDEGISQGEVISGLWANIALHGMEKIVKEFAYSLSGKKVKNEKEITLVRYADHFVILHPNLNVVTKAKALVEEFLRGMGLELKPEKTRLTHTLIQVGEEEPGFNFLGFNIRQYPVGKYTTGKNTYGKPLGYKTYIMPSKEEIKAHYQRLASEIDKFKSCKSQIDLIKGLNPIITGWSNYYSKVNSAKTFKELDHLLTLKLIAWGKSRHHHKSIKETIKKYFGTKGKSNWIFKTIENGNRICLVYHEDFQIKNFVKVKGESSPYDGNLIYWTTRMGKSAE
>NC_008312.1|WP_155994251.1|680661_680802_-|hypothetical-protein
MLNDQQKLPKCSRNNQENIQNVVCTSPDEDVMEREDKLQTAVIGLL
>NC_008312.1|WP_011610284.1|678195_678477_-|RP-ribonucleotide-reductase-like
MRGDIGTTPAELRRELTEVKCHQDKAKAEIFVGDSRQGWVESYRALLELSTDKQFSGKVNVIIDLSHVRPAGEPLKGFGGVANPVKLVRLVGH
>NC_008312.1|WP_011610282.1|675848_677618_-|RNA-directed-DNA-polymerase
MEKAKTLKRRMDKPESFLSVAWDTDDIPDKICVNPNLKWRDIDWKKVEKNVFKLQKLIYRASSRGEIRKMRKYQKLLIKSHDALLLAVRNVTQDNQGKKTAGIDGIKNLPPMQRLHLVDLLKSRDLKASPTQKVSIPKTGRNQKRRLGIHSLYDLGLQTLVKLGMEPEWEAHFETNTYGFRPGRSTDDAIQAIYLSINDEPKYVLNADISKCMSEVNHHALLGKIDKSPYRQLVKQWLKSGVFDKSQFDPPLLELGTPQGEVISPLLANIALHGMEKCLQDFAETLPGNKRDNIQALSLVRYAGNFVILHKDIEVVMQAKAVVQEWLNNIGLELKPEKTRIAHTLEEYEGNQPGFDFLGFTVRQWKVKTSKQGFKTLIKPSKQSINTHYRKMAEVCDTHKSATVKVLITKLNPIIREWANYFSAVVSNDIFQKLDHLLLRRIWRWASRRHSNKSAAWVKEKYFPHREGTKSWVLKDEEYILNLHSDVSIIRHVKVKDNKSPYDGDWIYWSSRMVNSPGIRKEVSTLLKKQKGKCAFCGLSFRPTDTMEVYHVIPRSEKGNSTSKNKELLHRHCHDTKTALERETSQSED
>NC_008312.1|WP_011610280.1|666286_669340_-|DUF4347-domain-containing-protein
MNSILKKATESIEINQNLQQVRQQKRLMVIDTRVENYRQLTTGVTPETKVALIDPKRDGIEQITELLSNYPTNSLHIVCHGDPGILYLGKTPISEQNLPKYTGYLQEWGIVDILLYSCNIASQSDNLLQLLHKFTGANIAASKHQVGNPLKGGTWDLESRIGSVASEIAFLPQVIQDYPGVFHGLQFYVGQDETGKVRAYLGKDDRVSNAYTNIFSDDYLTLSPVGIWDDREIEEKDTAFDYRYTNNASYFPGFTPQIDMFYETPVDGSPADDSFDRERNTYFQVNFLDELKVWNGEDFVATGGEVMTWSQENWDVNDKGEWYAEFANEVTTGEGVVKGKPYYYAVYDEPGNDHWHYVMELQEGTSPTGIDDGLYLLPIEVETNIPDSIPSDPVYILYNQNLSAAPDVDQDTILAAQNYLLEEYGMTEPAQEFKAFLDSSQNGVDSDATGLATFSLNAEQTEIEYTIELNGLDLIEDPVKRTAENAITEIHFHHRGYGTDGSHVLNVFGTPSEDDDNIEIDYENERIIGKWDWSDAAANFARHSEPKSDGVYGDWKAPKLEIEVVEAYNNGALGIKLRDEEPEDKLNIFEGTQLNFDNGARVKITENITISKAKSSIVEASILEGGDIPAGEIAILSPAQMPGTTPVTTSLFNLFHGNLYVQVHTNQNPEPGDIRGQVLPVRTLADAEDDVLSGGTGNELFELDAADVGGIEIEELAGRETLTLEGMETSMSNLHREDNDLIIDVNQDGSFQTAEDLTLKNFFADEVGVVGKGYIELVDEISGNEILRGVSSSGKDLVHGTSEDDIRQGKGGNDVISGFGGNDELYGNRGDDLLKGGDGNDILKGGYENDTLKGNSGNDTLIGWQGFDILLGGSGEDNLKGGIGRDRLNGGKDDDLLSGGASQDKFIFAANKTFSEADLGVDEITDFVSGPDKIILDVTVFTAIKTTPGESLDEGEFAVVDNETDVFSADATIVYNSANSTLYYNPNGVENGLGDGGSFALLSNEASLSADDFLVRA
>NC_008312.1|WP_155994249.1|664959_665259_-|hypothetical-protein
MRIYINGMGIRRIARVTGITHPTIINWIKHSGERLPDTYDPEQLPQVGELDELETFVIYRTYLGSFCRSGDRQSLKHKSNKTKINLGGGILKSSFKVFD
>NC_008312.1|WP_011610278.1|663632_663986_+|glyoxalase/bleomycin-resistance/dioxygenase-family-protein
MTVEFKHVMLMVKDVLASVKFYSEGLGLTVKTASPGWAELDANGTTIALHAAENPQGSDSPILSFHVDDVQGAIAALEPMGAKLEGRVREPSFGKVAAMRTPDGYLVSLLQPTKVSK
>NC_008312.1|WP_011610277.1|659041_662110_+|DUF4347-domain-containing-protein
MNSILKKATESIEINQNLQQVRQQKRLMVIDTRVENYRQLTTGVTPETKVALIDPKRDGIEQITELLSNYPTNSLHIVCHGDPGILYLGKTPISEQNLPKYTGYLQEWGIVDILLYSCNIASQSDNLLQLLHKFTGANIAASKHQVGNPLKGGTWDLESRIGSVASEIAFLPQVIQDYPGVFHGLQFYLGQDETGKVRAYLGKDDMVSNGYTNIFSNDYLTLGSVGISDQRLVPESDTAFEYSYTDNASSFPGFTPQAYMFYETPLDGSPADDSFVPERNTYFQVNFLDELKVWNGEDFVATGGEVMTWSQQKKSVINEDQFRELVNEVTTGEGVVKGEPYYYSEIREAGRDHWHYIMELQEGTSTTGIDDGLYLLEVEVETNVPDSIPSDPIYILYNQNLSPAPDADQNTILEAQNYLLENFGITEPAQEFKAFLDSSQNDGVESDATGIATFRLNADQTEIEYTIELNGIDLIEDPAERTADNAVTKINLHHRDYGINGDHVFNIFGVASEDDNDIEIDYENETITGKWDWSDAATNFTRHSEPKSGGTYGDRKSPELKIEVIEAYDNSNGTLGIKLQDGEPQDELDIFEGTKLKFENGTTVEFTENITIFQEFQEESSTAQVSLLEGDDILDGEIAILPPAQRSATTPVTTSLVHLFHGNLYVQVQTKQNFDPGDIRGQILPVRTLADAEDDVLSGGTGNELFELDAADVGGVEIKELAGRETLTLEGMETSMSNLHREDNDLIIDVNQDGSFQTAEDLTLKNFFADEVGVVGKGYIELVDEISGNEILRGVSSSGKDLVHGTSEDDIRQGKGGNDVISGFGGNDELYGNRGDDLLKGGDGNDILKGGYENDTLKGNSGNDTLIGWQGFDILLGGSGEDNLKGGIGRDRLNGGKDDDLLSGGASQDKFIFAANKTFSEADLGVDEITDFVSGPDKIILDVTVFTAIKTTPGESLDEGEFAVVDNETDVFSADATIVYNSANSTLYYNPNGVENGLGDGGSFALLSNEASLSADDFLVRA
>NC_008312.1|WP_011610290.1|685182_685695_-|adenine-phosphoribosyltransferase
MELKNLIREIPNFPKSGIIFRDITTLLSNTDGLHYTIDILTEKCLEFKPDYVVGIESRGFIFGMPLAYQLNVGFIPVRKPGKLPAEVYSVSYDLEYGQDSLEVHQDAMPAGSRVLVIDDLLATGGTAGATTQLIEKAKCNLVGFAFVIELKELGGREKLPKVPIISLIEY
>NC_008312.1|WP_011610291.1|687516_688122_+|DUF3038-domain-containing-protein
MELKTSPNPSKPLILDNLPNISLPNSGCPRRTKTQIDLMLLAIEALQLGGAEAMLKVVKELELQEIILSRVVLWRLRSTNPLRQNSQRLPLTLIEAKALVIIVCYLAKRLTVPIRKLLLDYQQLSQKQLPIESHLQLSFYLEQFRVHFRSRMNPRRSGVMAYNSEEKLNQLGLELLSKLLFCTGTRGMQRFWISLFDGEVT
>NC_008312.1|WP_155994253.1|688949_690566_-|CocE/NonD-family-hydrolase
MKILPKETTSIFTRDGIRLDADIYRPDAAGEFPVILMRQPYGRAIASTVVYAHPTWYAAHGYIVIIQDVRGRGTSEGEFELFAHEIEDGIDTINWAANLPGSTGEIGMYGFSYQGMTQLYAASAKSPVIKTICPAMIGYNLYTDWAYEGGAFCLQTNLGWAVQLATETAHLRGDEQAYQELYQASKNLPLSTTIPALPEVINEYGKDSFYHQWIENYQPGEYWQNLSPNMKNVDLPILHIGGWFDTYLRGTIHLYKEMAGRSKFLQKLIVGPWSHIPWGRKVGAVNYGLGASSFIDDIQILWFNQFLKGINTGIFERSPVSLFEMGSNEWRNLNSWPSNNYKFYYLASTGLANVREDSGSLTQSCPNISADDKFVHDPWRPVPALGGHATFPAGSFERSELDCRTDILTYTSEFFKEDLHIAGDISVDLHCTADTSSFDLSAVLSEVTKNGNVYNFTQGYIKVIDNNLPVTICLQPTCMKIQKGNAIRLSLSAACFPAYIINPGIDKSPGEVRLIDSKIITITVSSGKNYPSVISLSV
>NC_008312.1|WP_011610295.1|692629_693079_-|cupin-domain-containing-protein
MITRCMIPVVKSPQDYQAYRISPNDNNRLAIIFSPANANASLTVCLEVFDVGGKTPLHQHHFAVEMFFILKGEGKASCDGKSINICAGDSILMPPTGNHIIENTGSTRLYALCIMVPNEDFAELIRSGKPVDLDEEDIQVLTSSNFYKF
>NC_008312.1|WP_011610296.1|694773_695922_+|GTP-binding-protein
MQLTTTQLDNSNIDTPKHGLPVTIITGFLGSGKTTLLNHILQNQEGVKTAVLVNEFGEIGIDNELIVSTNADDTMVELSNGCVCCTINEDLVNAVYKILGKSEKFDYMVVETTGLADPLPVALTFLGTELRDMTRLDSIITLVDAANYSVDLFKSQAAHSQIVYSDIILLNKTDLADEAYLDLLEVKIRNLKKDARIIRTKKSQVALPLVLSVGLFESDKYFELAEVDQHHNHGHDHHDHDHEHEHHHHDHEHEHHHHDHGHEHHHHDHGHEHHHHEHDHYHSNHLENDGFTSISFQSDKPLSMKKFQHFLDNKLPANVFRAKGILWFQESSLRHIFHLSGKRFSIEDDQWNGNNHKNQLVFIGQNLDHEKLRSQLKDCVIS
>NC_008312.1|WP_011610297.1|696401_696863_+|D-tyrosyl-tRNA(Tyr)-deacylase
MRVVIQRVNFSQVKVNEEIVGKIGKGLNLLVAISTTDTEAEIDWIVRKCLDLRLFPDPDSNNNFWEKSVKDIDGELLIVSQFTLYGDCRKGRRPSFDNSASPEVAKQLYQLFVEKLKLSGLKVATGIFGAMMQVEIDNDGPVTFLLEKEANNK
>NC_008312.1|WP_011610298.1|697750_698074_+|DUF1825-family-protein
MGFFDSEVVQKEAKQLFEDYQSLIMLGSNYGKFDREGKKMYIEQMEAMMDRYKIFMKRFELSEDFMAKMTMEQLKTQLNQFGITPQQMFHQMNVTLERMKSELNHQS
>NC_008312.1|WP_155994635.1|698788_700603_-|PBP1A-family-penicillin-binding-protein
MLTSSLVAGGLVGLAISFRNLPDVRLLKNYTPSETTRIYDIKGRPLASLHDEANREVMPLKQISPDLKRAVLAIEDSNFYNHLGIYPIGIMRALVANLERGKTVEGGSTVTMQLVKNLFLSPTAKLSRKVAEAVLAIRMEQIMAKDEILELYLNQIYWGHNLYGVETAARSYFNKSSEDLTLAEAALMAGMIPAPEEYSPFINYKKSKQRQATVLARMRELNWITAQEEAEALKQPLYVGKVTSFGKSKLPYITSAVIQELTERFGKDAVLKGGMRIQTTIDMNFQKMAEKTVSEWHKILYYRGLYRSWDKGQLALVAVDPRTHFVKAMVGGADFKTSQYNRAVQAFRQPGSSFKPFVYYTAFASGRFTPSSVVIDAPVNYRDGTGYYSPRNYGGGYSGAVSIRKALQSSLNIPAVKIGQVVGLNKVIEVCRILGIKSPMEPVISLPLGSVDLTPLEMAGAYATFANNGWHSDTTFIVQVTDTSGNVLLDNTPKPKLVLNQWAVASLNSILVGVIEQGTATRARISRQAAGKTGTTSSERDVWFVGYTPQLSTAVWVGNDDYRPLNYGATGGTTVAPIWRDFMNQAMSGMRKEYFPPAYKFDRP
>NC_008312.1|WP_155994636.1|700845_702060_+|tyrosine--tRNA-ligase
MTDKFTWLHRGISEIFPDQPYSQDPNENLILKLTTLDRPLRVKLGIDPTGVDVHLGHSIPVRKLRAFQDAGHTAVLIIGDFTARVGDPTGKSEARRQLTPEQVQENAKTYLDQVRPILDFDTPGRLEIRYNSEWLSKLDLADILELLATMTVGQMLAKEGFALRYQQENPIYIHEFLYPLMQGYDSVAVDADVELGGTDQKFNIAVGRDLQRHFGKRTQFGLLMPILLGTDGVQKMSKSLGNYVGLSEDPLSMYSKLEKIPDDQVENYFELLTNLNINDIDKNPRERQKLLALDIVSQYHSQEAALEAQQTAVKMVIKGDMSQTEAVPEFSLASVEFPAKLFYVVSASGLCKSSSEARKKIAGGAVRLDDERISDQNFTLDSPADLDGKVLRVGKKNFVRLVKN
>NC_008312.1|WP_011610301.1|702712_703441_+|orotidine-5'-phosphate-decarboxylase
MNIDNIIVPLDVPNEAAAIALIEELPEIIWWKVGLELFVSCGPQIFSILKQRQKRIFLDLKFHDIPNTVAGVCRSAASYGVDLLTIHATAGRVALSRAQQAVLEGAKIIGQKPPRLIAITILTSLTSRDLAFDLKIPLELPEYVLQMALLAQESGLSGAVCSPQEVEQLRRVCGDDFLLVCPGVRPSWAEVGDQKRSLTPAQAIKAGANYLVIGRPITATADPREALRRICQEISGDQKEGS

Crispr_ID: NC_008312_6

• CRISPR_ID: NC_008312_6
• CRISPR_location: 904018-904108
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NC_008312_6

Consensus_repeat	Method
GAGGTTTCTGAGACAGAAAATACTGATAATT	CRISPRCasFinder

spacers of NC_008312_6

>6.1|904049|29|NC_008312|CRISPRCasFinder
ATAATGGGGAAATTGTAGATGATAATTCG

CRISPR arrays and Neighbor proteins around NC_008312_6

CRISPR arrays

The CRISPR arrays of NC_008312_6

>merge|NC_008312|6|904018-904108|CRISPRCasFinder
GAGGTTTCTGAGACAGAAAATACTGATAATTATAATGGGGAAATTGTAGATGATAATTCGGAGGTTTCTGAGACAGAAAATACTGATAATT

>NC_008312|6|4|904018-904108|CRISPRCasFinder
GAGGTTTCTGAGACAGAAAATACTGATAATT	ATAATGGGGAAATTGTAGATGATAATTCG
GAGGTTTCTGAGACAGAAAATACTGATAATT

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_008312.1|WP_011610420.1|932939_934169_+|tryptophan-synthase-subunit-beta	unknown	unknown	gnl|CDD|235288
NC_008312.1|WP_044136325.1|923659_923875_+|hypothetical-protein	unknown	unknown	unknown
NC_008312.1|WP_011610415.1|926398_927370_-|Rieske-(2Fe-2S)-protein	unknown	unknown	gnl|CDD|239551
NC_008312.1|WP_044136324.1|913572_923676_+|CHAT-domain-containing-protein	unknown	unknown	gnl|CDD|227328
NC_008312.1|WP_011610407.1|884920_886705_+|sodium:solute-symporter	unknown	unknown	gnl|CDD|271371
NC_008312.1|WP_011610419.1|931528_932113_-|pentapeptide-repeat-containing-protein	unknown	unknown	gnl|CDD|224276
NC_008312.1|WP_011610410.1|891342_901950_+|CHAT-domain-containing-protein	unknown	unknown	gnl|CDD|227328
NC_008312.1|WP_011610405.1|882333_882663_+|Uma2-family-endonuclease	unknown	unknown	gnl|CDD|99749
NC_008312.1|WP_011610421.1|934520_935816_+|serine-hydrolase	unknown	unknown	gnl|CDD|365903
NC_008312.1|WP_044136323.1|890950_891178_+|hypothetical-protein	unknown	unknown	unknown
NC_008312.1|WP_011610403.1|880081_881080_+|NAD(P)-dependent-alcohol-dehydrogenase	unknown	unknown	gnl|CDD|176237
NC_008312.1|WP_011610414.1|925475_926078_+|hypothetical-protein	unknown	unknown	gnl|CDD|369378
NC_008312.1|WP_011610417.1|929568_930585_+|ATP-phosphoribosyltransferase	unknown	unknown	gnl|CDD|270311
NC_008312.1|WP_011610418.1|930907_931135_+|ferredoxin-family-protein	unknown	unknown	gnl|CDD|224069
NC_008312.1|WP_044137141.1|887811_889149_+|tetratricopeptide-repeat-protein	unknown	unknown	gnl|CDD|276809
NC_008312.1|WP_011610416.1|927460_929014_+|histidine--tRNA-ligase	unknown	unknown	gnl|CDD|273080
NC_008312.1|WP_011610406.1|882851_883628_-|hypothetical-protein	unknown	unknown	gnl|CDD|373106
NC_008312.1|WP_011610409.1|889555_890587_+|hypothetical-protein	unknown	unknown	unknown
NC_008312.1|WP_011610404.1|881100_882081_+|zinc-binding-dehydrogenase	unknown	unknown	gnl|CDD|176232
NC_008312.1|WP_011610402.1|878410_879826_+|bifunctional-UDP-N-acetylglucosamine-diphosphorylase/glucosamine-1-phosphate-N-acetyltransferase-GlmU	unknown	unknown	gnl|CDD|184646

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_008312.1|WP_011610420.1|932939_934169_+|tryptophan-synthase-subunit-beta	gnl|CDD|235288	PRK04346, PRK04346, tryptophan synthase subunit beta; Validated.	0
NC_008312.1|WP_011610410.1|891342_901950_+|CHAT-domain-containing-protein	gnl|CDD|227328	COG4995, COG4995, Uncharacterized protein conserved in bacteria [Function unknown].	5.08925e-108
NC_008312.1|WP_044136324.1|913572_923676_+|CHAT-domain-containing-protein	gnl|CDD|227328	COG4995, COG4995, Uncharacterized protein conserved in bacteria [Function unknown].	7.38696e-109
NC_008312.1|WP_011610407.1|884920_886705_+|sodium:solute-symporter	gnl|CDD|271371	cd11477, SLC5sbd_u1, Uncharacterized bacterial solute carrier 5 subfamily; putative solute-binding domain. SLC5 (also called the sodium/glucose cotransporter family or solute sodium symporter family) is a family of proteins that co-transports Na+ with sugars, amino acids, inorganic ions or vitamins. Prokaryotic members of this family include Vibrio parahaemolyticus glucose/galactose (vSGLT), and Escherichia coli proline (PutP) and pantothenate (PutF) cotransporters. One member of the SLC5 family, human SGLT3, has been characterized as a glucose sensor and not a transporter. This subfamily belongs to the solute carrier 5 (SLC5) transporter family.	1.75553e-105
NC_008312.1|WP_011610419.1|931528_932113_-|pentapeptide-repeat-containing-protein	gnl|CDD|224276	COG1357, COG1357, Pentapeptide repeats containing protein [Function unknown].	1.98459e-27
NC_008312.1|WP_011610415.1|926398_927370_-|Rieske-(2Fe-2S)-protein	gnl|CDD|239551	cd03469, Rieske_RO_Alpha_N, Rieske non-heme iron oxygenase (RO) family, N-terminal Rieske domain of the oxygenase alpha subunit; The RO family comprise a large class of aromatic ring-hydroxylating dioxygenases found predominantly in microorganisms. These enzymes enable microorganisms to tolerate and even exclusively utilize aromatic compounds for growth. ROs consist of two or three components: reductase, oxygenase, and ferredoxin (in some cases) components. The oxygenase component may contain alpha and beta subunits, with the beta subunit having a purely structural function. Some oxygenase components contain only an alpha subunit. The oxygenase alpha subunit has two domains, an N-terminal Rieske domain with an [2Fe-2S] cluster and a C-terminal catalytic domain with a mononuclear Fe(II) binding site. The Rieske [2Fe-2S] cluster accepts electrons from the reductase or ferredoxin component and transfers them to the mononuclear iron for catalysis. Reduced pyridine nucleotide is used as the initial source of two electrons for dioxygen activation.	8.80682e-34
NC_008312.1|WP_011610405.1|882333_882663_+|Uma2-family-endonuclease	gnl|CDD|99749	cd06260, DUF820, Domain of unknown function (DUF820). This family consists of hypothetical proteins that are greatly expanded in cyanobacteria. The proteins are found sporadically in other bacteria. They have been predicted to belong to the PD-(D/E)xK superfamily of nucleases.	3.753e-16
NC_008312.1|WP_011610421.1|934520_935816_+|serine-hydrolase	gnl|CDD|365903	pfam00144, Beta-lactamase, Beta-lactamase. This family appears to be distantly related to pfam00905 and PF00768 D-alanyl-D-alanine carboxypeptidase.	5.01057e-58
NC_008312.1|WP_011610403.1|880081_881080_+|NAD(P)-dependent-alcohol-dehydrogenase	gnl|CDD|176237	cd08276, MDR7, Medium chain dehydrogenases/reductase (MDR)/zinc-dependent alcohol dehydrogenase-like family. This group is a member of the medium chain dehydrogenases/reductase (MDR)/zinc-dependent alcohol dehydrogenase-like family, but lacks the zinc-binding sites of the zinc-dependent alcohol dehydrogenases. The medium chain dehydrogenases/reductase (MDR)/zinc-dependent alcohol dehydrogenase-like family, which contains the zinc-dependent alcohol dehydrogenase (ADH-Zn) and related proteins, is a diverse group of proteins related to the first identified member, class I mammalian ADH. MDRs display a broad range of activities and are distinguished from the smaller short chain dehydrogenases (~ 250 amino acids vs. the ~ 350 amino acids of the MDR). The MDR proteins have 2 domains: a C-terminal NAD(P)-binding Rossmann fold domain of a beta-alpha form and an N-terminal catalytic domain with distant homology to GroES. The MDR group contains a host of activities, including the founding alcohol dehydrogenase (ADH), quinone reductase, sorbitol dehydrogenase, formaldehyde dehydrogenase, butanediol DH, ketose reductase, cinnamyl reductase, and numerous others. The zinc-dependent alcohol dehydrogenases (ADHs) catalyze the NAD(P)(H)-dependent interconversion of alcohols to aldehydes or ketones. Active site zinc has a catalytic role, while structural zinc aids in stability. ADH-like proteins typically form dimers (typically higher plants, mammals) or tetramers (yeast, bacteria), and generally have 2 tightly bound zinc atoms per subunit. The active site zinc is coordinated by a histidine, two cysteines, and a water molecule. The second zinc seems to play a structural role, affects subunit interactions, and is typically coordinated by 4 cysteines.	0
NC_008312.1|WP_011610414.1|925475_926078_+|hypothetical-protein	gnl|CDD|369378	pfam07466, DUF1517, Protein of unknown function (DUF1517). This family consists of several hypothetical glycine rich plant and bacterial proteins of around 300 residues in length. The function of this family is unknown.	1.36013e-29
NC_008312.1|WP_011610417.1|929568_930585_+|ATP-phosphoribosyltransferase	gnl|CDD|270311	cd13593, PBP2_HisGL3, The catalytic domain of hexameric long form HisGL3; contains the type 2 periplasmic binding protein fold. Encoded by the hisG gene, the ATP phosphoribosyltransferase (ATP-PRT, EC 2.4.2.17) is the first enzyme in histidine biosynthetic pathway that catalyzes the condensation of ATP and PRPP (5'-phosphoribosyl 1'-pyrophosphate), and is regulated by a feedback inhibition from the product histidine. ATP-PRT has two distinct forms: a hexameric long form, HisGL, containing two catalytic domains and a C-terminal regulatory domain; and a hetero-octomeric short form, HisGs, without the regulatory domain. HisGL is catalytically competent, but the hetero-octameric HisGs requires the second subunit HisZ, a paralog to the catalytic domain of functional histidyl-tRNA synthetases (HisRSs), for the enzyme activity. This catalytic domain belongs to the type 2 periplasmic binding fold protein superfamily (PBP2). The PBP2 proteins are typically comprised of two globular subdomains connected by a flexible hinge and bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap. The majority of PBP2 proteins function in the uptake of small soluble substrates in eubacteria and archaea.	4.19689e-109
NC_008312.1|WP_044137141.1|887811_889149_+|tetratricopeptide-repeat-protein	gnl|CDD|276809	sd00006, TPR, Tetratricopeptide repeat. The Tetratricopeptide repeat (TPR) typically contains 34 amino acids and is found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi, plants, and humans. It is present in a variety of proteins including those involved in chaperone, cell-cycle, transcription, and protein transport complexes. The number of TPR motifs varies among proteins. Those containing 5-6 tandem repeats generate a right-handed helical structure with an amphipathic channel that is thought to accommodate an alpha-helix of a target protein. It has been proposed that TPR proteins preferentially interact with WD-40 repeat proteins, but in many instances several TPR-proteins seem to aggregate to multi-protein complexes.	4.76948e-11
NC_008312.1|WP_011610416.1|927460_929014_+|histidine--tRNA-ligase	gnl|CDD|273080	TIGR00442, hisS, histidyl-tRNA synthetase. This model finds a histidyl-tRNA synthetase in every completed genome. Apparent second copies from Bacillus subtilis, Synechocystis sp., and Aquifex aeolicus are slightly shorter, more closely related to each other than to other hisS proteins, and actually serve as regulatory subunits for an enzyme of histidine biosynthesis. They were excluded from the seed alignment and score much lower than do single copy histidyl-tRNA synthetases of other genomes not included in the seed alignment. These putative second copies of HisS score below the trusted cutoff. The regulatory protein kinase GCN2 of Saccharomyces cerevisiae (YDR283c), and related proteins from other species designated eIF-2 alpha kinase, have a domain closely related to histidyl-tRNA synthetase that may serve to detect and respond to uncharged tRNA(his), an indicator of amino acid starvation; these regulatory proteins are not orthologous and so score below the noise cutoff. [Protein synthesis, tRNA aminoacylation].	1.56873e-99
NC_008312.1|WP_011610406.1|882851_883628_-|hypothetical-protein	gnl|CDD|373106	pfam14517, Tachylectin, Tachylectin. This family of lectins binds N-acetylglucosamine and N-acetylgalactosamine and may be involved in innate immunity. It has a five-bladed beta-propeller structure with five carbohydrate-binding sites, one per beta sheet.	0.000422951
NC_008312.1|WP_011610418.1|930907_931135_+|ferredoxin-family-protein	gnl|CDD|224069	COG1146, COG1146, Ferredoxin [Energy production and conversion].	8.29168e-10
NC_008312.1|WP_011610404.1|881100_882081_+|zinc-binding-dehydrogenase	gnl|CDD|176232	cd08271, MDR5, Medium chain dehydrogenases/reductase (MDR)/zinc-dependent alcohol dehydrogenase-like family. This group is a member of the medium chain dehydrogenases/reductase (MDR)/zinc-dependent alcohol dehydrogenase-like family, but lacks the zinc-binding sites of the zinc-dependent alcohol dehydrogenases. The medium chain dehydrogenases/reductase (MDR)/zinc-dependent alcohol dehydrogenase-like family, which contains the zinc-dependent alcohol dehydrogenase (ADH-Zn) and related proteins, is a diverse group of proteins related to the first identified member, class I mammalian ADH. MDRs display a broad range of activities and are distinguished from the smaller short chain dehydrogenases (~ 250 amino acids vs. the ~ 350 amino acids of the MDR). The MDR proteins have 2 domains: a C-terminal NAD(P)-binding Rossmann fold domain of a beta-alpha form and an N-terminal catalytic domain with distant homology to GroES. The MDR group contains a host of activities, including the founding alcohol dehydrogenase (ADH), quinone reductase, sorbitol dehydrogenase, formaldehyde dehydrogenase, butanediol DH, ketose reductase, cinnamyl reductase, and numerous others. The zinc-dependent alcohol dehydrogenases (ADHs) catalyze the NAD(P)(H)-dependent interconversion of alcohols to aldehydes or ketones. Active site zinc has a catalytic role, while structural zinc aids in stability. ADH-like proteins typically form dimers (typically higher plants, mammals) or tetramers (yeast, bacteria), and generally have 2 tightly bound zinc atoms per subunit. The active site zinc is coordinated by a histidine, two cysteines, and a water molecule. The second zinc seems to play a structural role, affects subunit interactions, and is typically coordinated by 4 cysteines.	1.44684e-170
NC_008312.1|WP_011610402.1|878410_879826_+|bifunctional-UDP-N-acetylglucosamine-diphosphorylase/glucosamine-1-phosphate-N-acetyltransferase-GlmU	gnl|CDD|184646	PRK14360, glmU, bifunctional UDP-N-acetylglucosamine diphosphorylase/glucosamine-1-phosphate N-acetyltransferase GlmU.	0

Protein sequences

>NC_008312.1|WP_011610410.1|891342_901950_+|CHAT-domain-containing-protein
MKPNSSKLCTIKALSLILGTLATTPANSQPITPAKDGTNTTVTPQGQQFNIKGGTRSGANVFHSFDKFNVHSGQTANFVTTPDTRNVLGRVKGGASYINGLIQVLGSSSNLFLMNPAGIMFGPNASLNVPASFSVTTATGIGFDQNNFWFKAMGTNDYSNLLGSPSGYRFDVSKPGSIVNEGSLTLNSGENLTLLGGTVVNTGELSSPGGNITVTAVEGGSTLKISQPGHLLSLEVPLEDGENISNIDPLSLPELLAGGGDVVEATSVIVKENGDVVLTGSNTMVAETPGTATISGKIDVSTTASSLQNEGGASFGSQVNVWGDRVALIDTNIKADGKNGGGTVLIGGDFQGLGIVPNSQHTFVNNNSFISADAITNGDGGQVRIWSDGITNFAGNISAKGGTSSGNGGLVKIGGKEQLIFDGKVDVTAALGTEGTILLDPESVTVGEDNSEGEKEIVEDNSEVSETENTDNYDGEIIEDNSEVSETENTDNSTTKNTDNLEDKETENPLDPFAADENSDVTISADNLGELSGNVIIDADNDITINERIETDSSVELKAGRSININADIDTKSGNGNIDLLGNNDEMNLANRSDGKASINQLDGTILNAGSGGINIKLGSLGEVGDINLGNLRTTGKVLVDANGGNIVRVSENSLINAGSVLFRTSGNGGIGFVGEPLRLDVQNLEAVSGSGGVFFDVGNVNIGGVSEDVDGIATFGGDVDIKSAGNVTLNETISSNEVVENNSEATSTENTEVVDGGGGINIEAAGDIVATGSGIKGGGEAVSLSGTNIRINDEFDETSGDADVKLSATNDIVVEDIEDDALEFMPGRGKIEFRADLDGDGFGLVEMLDNKPDVGSNPDVFDNGADTIKTNGRGLTIAGAGLVLGNVDTSWLPVYSGGELLKAIDVDEGGPIPPGVEDKSGLISEEDFDWSSSGVDDEGRYYGGKITIDGQSYNVYYDGYDDEKKVSKYTINGQSYYQAGVEGKLYYVPATKTWEDTATFTFTVDGDLGTVKNIDVRFSAAHTYNKQLEVSLESPQKTKVQLFTGVGSYGGENFQDTVLDDNASRSIDNGLAPFDGTYRPQGSLADFNGENPNGTWTLTVKDTNIEYGNGTLYRAGETAHWGTTAIGTQLLLRNPLVQIAAGGNGGAINLEATHGDISVGNIRSLSETANGGRIDLNANKDIISGLINSSSERGNGGDVNLNAISGEISTFSLDTSSFDGDGGSVEMKALGDITTKAEMMTDSGEFFVDDYGYVENTSGGGGNAGNIKIESTEGSIDTKAGSISAGSVSGNGGAIDLDAGGDIKTENLYPGSYSRSGNSGNGGAIDLDAGGDIKTENLYPGSYSRSGNSGNGGAIDLDAGGDIKTENLYPGSYSRSGNSGNGGAIDLDAGGDITTQYLYSSSYSESGNSGNGGAIDLDAGGDIKTENLYPGSDSSSGNSGNGGAIDLDAGGDITTQYLYSGSDSWEDNSYSGSYSGSGKSGNGGAIDLDAGGDITTQDLDSRSFSYGGDSGNGGDITLNAKQINPPEDGNAEKLTIYTFSVGSTDSKKAGDVNITTNNLSNTDILTLSSHSESGKVTIKSKTQEPLQIKDSSIITSEQVTVEIFGEQIQIETGNTQSGDVFINSDGDLNLNNVTIESDTKSNQAAGDVNIYSRGNITLENTDIISTTNSQGNAGQITLETNENIELTNNSKILANTEGTGNAGQINIEANNLILDQNTKLITETARAGNPGDIKIQANTIDIGEGAKASTTVLTGSTSTGEGGNITINTNKLNVTGKLGIFAETEASKNAGILRISPYKNNPDLDITFKNDGFISASTSSTGNGGNIFIKAPENINITGQGFIATKTSGTGNAGIIDIKTNNLRISNGVKINASTEDQGNAGAIKINTTDFTLKKGTSLTTETNSAGLAGNIEINTKKLTIGQNAQISATALEGASNKEAGGNITINANNLDISGKLGIFAETAGESPAGTLTLNPYKNNPNLNIEFKQQGFISARTTSSGNGGNINIQAPEKINITGDGKISAETTGSGNAGTINIQTENLNLSEQVAISAETNSQGQAGNIEINSQTVTIGKGTEISATAGKKATSTGDGGNITINTNDLEISGKLGIFAETKGASNAGTLTITPYKTNPDLNSKTDPNINITFTDQGFISASTKSLGKGGDINILAPENINITGDGRITVEAKGSGDAGIINIETKNLTIAENTKISASTSDSGNGGEIKINSSETFQQQGRILTETTGTGDGGIINIEAGEITAPNSKISAKSTGAGNAGTIDITAQGDITTGVVTSAAKNKRETADGGSISITSQQGKINATRAIQSFSEGGNAGNVTLKAQTDITANTISSHGKQEGGQITIRSETGNIDTSSGKFLANYSGGGDAGDITMEAPQGNITTNNIYSYADGDGGQINIKAGNNINIEANSNIISASEPPSEGNSDKQGKGGDITLEAGNNINTTAANIYSGANEGDTGQIDITADNAIETGKIDLASGFVRQETKVNQNLVLIPKPGEPATKGKAGDIRLRSRNSTIDTTGGTINSRSPDGTGDIIINAKGNISTGKLEASALNPDNPTTGGDVNITSEQGEINATQNIETFSEKGTAGDVNITAAGHINTNTIRSDGMEQGGDINIRSDSESSIDAAGALQTYSDAGTAGNVNLTSPGNVNISGIRSEGMEQGGDITLKSQGGEINSTGDIDSYSKQGKGGYVKVDAPERVNLANVSSYGMTESGDLITQSQQAEVNTGNVTTQASEGKSGRIVINGTEVGTGNLSSIAGTSAGEINVEATDGSIATYDIEMTSGGTLGALTLRAPENINTGDIRQKAGEGDANANIFSGGNQTTGNISQEAGNNTNLNQNAGENINAGNIEQNAGNNTNLNQTAGENINAGNIEQNAGNNTNLNQTAGENINVGNIEQNAGNNTNLNQTAGENINTGDIEQNAGNNTNLNQTAGENINTGDIEQNAGNNTNLNQTAGENINTGDIEQNASNNTSIYQIAEGEINTPVINQTFGNETTLNQISVRDVNTPVISNNNIPNNQGLNQENFSNNNNNNIENNSTTNSSNNKNISSTLTQSQRSELISTSTPSNNNQTTNTNTAQEQTESSINSTTDTQKILNIIDTVNTNSLTVATGSDQVITMLEQNLTNEYSNYFGTDFKEQFINQKTPREILTDMAAKTGKESAVVYINAYPEELQIILYTKDGQPILKTIPEANRKKLEKVVINFLKLTTSPAYRDFNSYLSPAKQLYDWFIAPISAELEAANIDTLLFSMGEGLRILPVAALHDGKQFLIEKYSLSLIPSISLMDTNYRPLQGTQVLAMGASKFINEKPLPAVPVEIETISEQLWEGSKFLNEEFTKNNLLTQRKNYPYPIIHLATHATFNRGKPSNSYIQLWGNEQIKLDQVRELGWSTPSVDLLVLSACRTAVGNREAELGFAGLAVAAGVKSALTSLWTVSDEGTLALMTEFYTHLNDAKIKSEALRQAQLAMLQGQVLITGGELRGSSTRGGVELPSAFANVNNQNLSHPYYWAGFTIVGSPW
>NC_008312.1|WP_044136323.1|890950_891178_+|hypothetical-protein
MVAGLAKSVYGGTVRLQGSKYMKVEALKEKDSTAQCYGLSAYLMNLPRENVRKQLNQIVYILIYLLLLGASNYLK
>NC_008312.1|WP_011610409.1|889555_890587_+|hypothetical-protein
MVNFSLSLKRKIQTALTLTVMGWAMPAFSAPTHILINVEGNVQVKKSKWKDFNKIEAGITLNSQDKIKVIDNASATIYCSDKTKWIIDKPGIHSISDGCSEGSKISLLDQGNNHSTRGPKAPAFEESLEKLPYLVSPRKTYVLNAPLTIRWNEVPGATNYKVKVEDWERETKECQISYDGELEPGGYYRITIVANNGATSQDEYGSEEKNNNWFMVLEDEEAEALQEELRQKLEALKEADKTQEEKDWSLAMFYLDKELNFDVIQILEGLVKSGSQKLEVYYLLGDIYQKLGLNLMAKDIFQQGLALSVQQGNSEYKGSIQQRLEWLEPSLGIINKAGELLRR
>NC_008312.1|WP_044137141.1|887811_889149_+|tetratricopeptide-repeat-protein
MIELEKRELEKRELEKIVLVYKELLEKLTAPNASLSEQEALKILLARDAISNALYNNLENCNLAVIEIKKLDKKLKDNSDKLIDFIILDEYRNNFPSLPKNWWWYLDIDVEKKRIESHPWNRFDGLIRIIRVMVWTVNLTLLGTLGSLFLVSGSGLQGVLAITFPGILSLLQAQSELTENGKKGFDKLLEKIKLPQHYQEEAKLGSTLLITGLLLTIWLNLPSISNSYKLRGKKSEEQENLALAEESYLQAINLYPDNVDARYKLAKIYEQLQDFDSAKKQHILAAQAGFIDAYNDLAYLYIQEGKNGEAIDLLRKALGLLEKKENQFEELMDSEKLNLKTQTYNIYKNLGWARFEQNQYDDSVSYLLPAMAIAQNTKYKQYIRSPGAAFCIYAKILSSTDEKSSGTQKTWQQCRELLESRLAAGESINPEEDTWLYEAKQQLNN
>NC_008312.1|WP_011610407.1|884920_886705_+|sodium:solute-symporter
MHLIDYIIVGLYLFAIVLFGIFLQRKASAGIDSYFLGDRNMPWWVLGASGMASNTDIAGTMLITALVYALGTKGFFLELRGGIALILAMFMIFMGKWNRRAQVMTLAEWMHLRFGVGREGNIARIVSAIAAIILTIGRISYFAIGGGKFLGEFIAVDARLASIIIIFLALIYTVISGFYGVVLTDLFQGVLIFFAIIYICAIAIQLPPLPETFAISIPGTNQLQEWNFREWSSIFPSMKVDLPGDYGRFNLFGAILCFYLLKVLMEGFGGIGGYMMQRYFAAKSDREVGLMSLWWIFLLSFRWPLVTAFAILGINYGITNQVISDPELVLPTVIATYLPVGIKGLILACFIAAGMSTFDSLINGGAAYWVKDIYQAYLDPLADNRKLMFQSRWASVIIAMVGLLFSFSISNINEIWGWLTLGLGTGLAVPLLLRWYWWRFNGYGFATGIAAGMIAAIITKAIVLPSLLDLQIAEFIQFLIPSSCSLAGCIVGTLLTPATERLVLENFYTITRPFGFWKQIATNVPHYLREKITLENQQDLLATAIAIPWQIVLCLTGIMFVMKRWDNFKILCFLLIILSICLYFAWYRYLKVKN
>NC_008312.1|WP_011610406.1|882851_883628_-|hypothetical-protein
MKKLLSCLLLSVAATSALTTSAQAGTFYVSTNDNQIGAFDDLTGSYTQLASTPTFTDIALSPSEQLFGITFNKLYSVDLDSGTNNYVGRLGKGKSLNALGFSNDGKLYGTGGSSFYSIDTSSGRASRISSNSGFSSSGDIVFDAARDIFWATSVGDSLWSITRDGVGTKIGDIGYGGVYGLAFGDDGSLFGYTANQDQLELDLGTGVGTFVRKIPGLNSQEIWGATSEADGTAVPEPGMTLGLLSVGALFVGSRLQRK
>NC_008312.1|WP_011610405.1|882333_882663_+|Uma2-family-endonuclease
MIPQEYLDWEEKQPIKYGYMNSQVLAMTGGTIPYNEISLNLATALKAQMRGKGCKVLMADAKLGVSGKRPFYYPDVMVTCDQRDRRATKIIYHPCLVVEDFVLEEVGEY
>NC_008312.1|WP_011610404.1|881100_882081_+|zinc-binding-dehydrogenase
MKALVLEKPGIPDSLYITEIPLPQPAAGEIRVQVHAVGLNPVDYKLAAGGFSTWSYPFILGLDVAGVVDAVGTDVTEWQVGEQVYYHGNLSKPGAYAEYTNANALAVAPLPEGISFTKAAAIPCAGFTAYHALHHRLHIQSKQTILIHGGAGGVGSFALQLASLAGLEVITTCSQSNFDYVQKLGAKHLIDYKNQDVVIRVKEITNDRGVDAILDTVGSETATTGLKMLAFNGGIACIAALPDFSNFKSFSLAASIHQIALGGAYLSGDKKAIQDLGKMGREMGELVREKKVSPMLTEVISLEEIPKALNRLKGRHVRGKIVAEIR
>NC_008312.1|WP_011610403.1|880081_881080_+|NAD(P)-dependent-alcohol-dehydrogenase
MKAFEVREFGNLVCTERPQPEPKFGEVLVKVKAVSLNYRDILMVKGAYNPHLPLPVIPCSDGVGEVVSVGEGVTKVKPGDRVASIFMQKWLSGNLTREAARSALGGEIDGMLAEYVILSEDGVVNIPSYLSDIEAATLPCAAVTAWHALIEAGLKPGETVLVMGTGGVSLFALQFAVMAGARVIATSSSDEKLARVKQLGASDMINYKSVPKWEKQVLALTEGTGVDYVVEVGGAKTLSQSLKAVKIGGQISLIGILAGAQAEFNILPALMKEVRIHGIFVGSRQMFEAMNRAIDLSQLHPVCDRIFPFESAPEALSYMEIGSHFGKITIQF
>NC_008312.1|WP_011610402.1|878410_879826_+|bifunctional-UDP-N-acetylglucosamine-diphosphorylase/glucosamine-1-phosphate-N-acetyltransferase-GlmU
MVAVAILAAGRGTRMKSDLPKVLHQLGSCTLVKRVIKSCVSIQPSKIMVIVGYRGGLVQKSLLDNNNNIDNDNTPTLEFVEQTEQLGTGHAIQQLLPYLKDFSEELLVLNGDVPLLRPETIKQLIDTHQQNKNSATILTANLPNPKGYGRIFCNTNNFVTQIVEERDCTAAQTKNHRVNAGVYCFNWPALANILPKLKADNDQQEYYLTDVVPLLDPVMAVDVNDYQEIFGINNRKHLAKAHEILQVRVKDDWMEAGVTLIDPDSITIDDTVLLQQDVIVEPQTHIRGSSIIGSGSRIGPGSLIENSHIGKNTSVLYSVISDSMVADNTRIGPYAHLRGDSQVGSHCRIGNFVELKKATVGDRSNAAHLSYLGDATLGEKVNIGAGTITANYDGVKKHKTKIGDRSKTGSNSVLVAPVTLGEDVTVAAGSVVTKNVEDDSLVIGRARQAVKKGWRLKQSDESKKEENKSSP
>NC_008312.1|WP_044136324.1|913572_923676_+|CHAT-domain-containing-protein
MKPNSSKLCTITALSLILGTLATTPANSQPITPAKDGTNTTVTPQGQQFHIKGGTRSGTNVFHSFDKFNVHSGQTANFVTTPDTRNVLGRVKGGASYINGLIQVLGSSSNLFLMNPAGIMFGPNASLNVPASFSVTTATGIGFDQNNFWFKAMGTNDYSNLVGNPSGYRFDVSKPGSIVNEGNLTLKPQGNLTLSGGTVVNTGELSSPGGNITVTAVEGGSTLKISQPGHLLSLEVPLEDGENISNIDPLSLPELLAGGGDIVEATSVVVKENGDVVLNGSNTMVAETPGTATISGKIDVSTTATSLKEKGRVPSQRKKEGAASPGKIDVPPSLKEKRDVAKAGKVNVWGDRVALIDTNIKADGKNGGGTVLIGGDFQGLGIVPNSQHTFVNNNSFISADAITNGDGGQVRIWSDGITNFAGNISAKGGTSSGNGGLVKIGGKEQLIFDGKVDVTAALGTKGRILLDPESVTVGEDNSEGEKEIVEDNSEVSETENTDNYDGEIIEDNSEVSETENTDNYNGEIVEDNSEVSETENTDNSTTKNTDNLEDKETENPLDPFAADENSDVTISADNLGELSGNVIIDADNDITINERIETDSSVELKAGRSININADIDTKSGNGNIDLLGNNDEMNLANRSDGKGSINQLDGTILNAGSGGINIKLGSLGEVGDINLGNLRTTGKVLVDANGGNIVRVSENSLINAGSVLFRTSGNGGIGFLGQPLRLDVQNLEAVSGSGGVFFDVGNVNIGGVSEDVVGIATFGGDVDIKSAGNVTLNETISSNEVVENNSEGGTTENTEVVDGGGGINIEAAGDIVATGSGIKGGGEAVSLSGTNIRINDEFDETSGDADVKLSATNDIVVEDIEDDVLEFMPGSGEIEFRADKDGDGFGLVKMLDNKPDVGSNPDIFENGADTIKTNGRGLTIAGAGLVLGNVDTSWLPIYSGGGELLKAIDVDEGGPIPPEGTEGTTTFTFTVDGDLGTVENIDVRFSAAYTHTGDLDVSLESPQGKVVQLFAGVGRWGDNFQDTVLDDNASRSIGISNAPFDGRYSPQGSLVDFNGENPKGIWTLKVKDTNIFSNLADGNLYRAGETAPWGTAIGTQLLLHNPLVKIAGGIESGKGGAINLEATHGDISVGNIRSLSEAANGGRIDLNANKDIITGLINSSSASVQGNGGAIDLDAGGNITTQSLNSRSYSWEGNSGNGGTIDLDAGGNITTQSLYSSSYSGSGNSGDGGAIDLDAGGDITTTQDLDSSSYSWESNLGNGGAIDLDAGGNITTQVLDSRSFSWEGNSGNGGAIDLDAGGNITTQILDSCSYSGSYDSGNGGAIDLVAGGDITTQNLYSDSFSRSGNSGNGGAIDLVAGGDITIQDLYSFSYSGSGNSGNGGDITLNAKQINPPEDGNAEKLTIYTFSAGKKESEEGKGGDVNITTNNLSNTDILTLSSHSGSGKVTIESQTQEPLQIKDSSIITSEKITITMPWGEEIQVETGDTQSGDVSINSSGDLNLSNVTIESDTESNQAAGDVNIYSRGNITLENTDIISTTNSQGNAGQITLESNQNIELTNNSKILANTEGTGNAGQINIEANKLILDQNTKLITETARAGNPGNINIQANTIDIGEGAKASTTVLTGSTSTGEGGNITINTNELNVTGKLGIFAETEASKNAGILRISPYKNNPDLDITFKNEGFISASTSSTGNGGNIFIKAPENINITGQGFIATKTSGTGNAGIIDIKTNNLRISNGVKINASTEDQGNAGEIKINTTDFTLEKGTSLTTETSSAGLAGNIEINTKNLTIGQNAQISATALEGASNKEAGGNITINANNLDISGKLGIFAETAGESPAGTLTLNPYKNNPNLNIEFKEKGFISARTTSSGNGGNINIQAPEKINITGDGKISAETTGSGNAGTINIQTENLNLSEQVAISAETNSQGQAGNIEINSQTVTIGKGTEISATAGKKATSTGDGGNITINTNDLEISGKLGIFAETKGASNAGTLTITPYQTNPDLNSKTDPNINITFTDQGFISASTKSLGKGGDINILAPENINITGDGRITVESEGSGDAGIINIETENLTIAENTKISASTSDSGNGGEIKINSSETFQLQGRILTETTGTGDGGIINIEAGEITAPNSKISAKTTDAGNAGTIDITAQGDITTGVVTSAAKNDIETADGGSISITSEQGKINATRAIQSFSEGGNAGNVTLKAQTDITANTISSHGKQEGGQITIRSETGNIDTSSGKFLANYSGGGDAGDITMEAPQGNITTNNIYSYADGDGGQINIKAGNNINIEGKSNIISASKSPSDGSSDMPGKGGDITLEAGNNINTRTAKIYSGANEGDTGKIDITADNAIETGKIDLVSGFVKEKEKVNENFTIIPKGEGEATQGKAGDIRLRSRNSTIDTTGGTINSRSPDGTGNIIINAKGNISTGKLEASALNPDKPTTGGDVNITSEQGEINATQNIETFSEQGIAGDVNITAFGQIQTNNISSQGMKRGGDINIRSDSESSIDAAGVLQTYSDAGTAGNVNLTSPGDVNISGIRSEGMEQGGDINIRSERGEINSTGDIDSYSKQGKGGYVKVDALERVNLANVSSYGMTESGDLIIQSQQAKVNTGNVTTQALEGKSGRIVINGTEVGTGNLSSIGTTSAGEIKVTATDGSIKTYNVEIRSDGTIGVLSLKATEDINTGDQTAIAGEGDVFIDNDAGDDLTTGDQTAITGEGDAFIDNDAGDDLTTGDQTAITGGGDVFIDNDAGDDLTTGDQTAITGGGDAFIDNHAGDELTTGDQTAITGGGDAFIDNDAGDDLTTGEKTVITGNVTATVTNFIQNDGVDQNLDTTVTNFIQNDGVNQNLDTTSVISNNNIPNNQVLNQENFSNNNNNNIENNSTTNSSNNKNILSNLTQSQRSELISNSTLSNNNQTTNTNTAQEQTESSINSTTDTQKILNIIDTVNTNSLTVATGSDQVITMLEQNLTNEYSNYFGTDFKEQFINQKTPREILTDMAAKTGKESAVVYINAYPEELQIILYTKDGQPILKTIPEANRKKLEKVVINFLKLTTSPAYRDFNSYLSPAKQLYDWFIAPISAELEAANIDTLLFSMGEGLRILPVAALHDGKQFLIEKYSLSLIPSISLMDTNYRPLQGTQVLAMGASKFINEKPLPAVPVEIETISEQLWEGSKFLNEEFTKNNLLTQRKNYPYPIIHLATHATFNRGKPSNSYIQLWGNEQIKLDQVRELGWSTPSVDLLVLSACRTAVGNREAELGFAGLAVAAGVKSALTSLWTVSDEGTLALMTEFYTHLNNVSIKAEALRQAQLAMLQGQVLITGGELRGSSTRGGVELPSAFANVNNQNLSHPYYWAGFTMVGSPW
>NC_008312.1|WP_044136325.1|923659_923875_+|hypothetical-protein
MVVLGNKNGQLIFNITNNVDPDEDGNKAFTIDGDRLLVNDSDDLNYETNPILNITIEASDRELTDAALCLD
>NC_008312.1|WP_011610414.1|925475_926078_+|hypothetical-protein
MGSWQDRLNKFTGKTRFVVSRLFIHLAGSEVTPLLGVLNKAAREAVGSEGDLQQVGEELVEVCKTLLQYDTYWQSAANEGDVVWDEAEAGDFFDELFTDSAQRYLSSGENEDYGENNEPLTLPPTGNLVVMITAAFEGEVPDIETDLASIEAMTQALKALINLHYQEKLRGIQIHFSPARLGDELDNEQLLVNFSELIPL
>NC_008312.1|WP_011610415.1|926398_927370_-|Rieske-(2Fe-2S)-protein
MYSNLPNSWFRVARSEDLSTKGVIPLHYFGKDFVLFRTEDGKPHIFDAHCPHLGAHLAHGGRIEGQTLRCPYHGWFWDTNGQCAATPYPNKAKPQVKIQNWPVLELNGLIMMYHHHQGKLPDWEIPQIPELMSEEWTPLRLVRQWKVRTTLQDYMDNSVDVSHLYNLHSRTFKSAHSYGVEIDGPMLTHRMSQKYNLSSLAAGKLVLEDGSVTTIYYGPAYDVSFYWTEGKLKLGLLTIFTGTPINNEYLDIAIFYSVKKVLPFPLSLILNKMLKQDVLETFEQDVSILENKKNIRNPLLYQNDGPVRQSRSWASQFYSENSA
>NC_008312.1|WP_011610416.1|927460_929014_+|histidine--tRNA-ligase
MQTIKVERVTGVNDILPSTYQIDQQIKSILSSNFESYGYRPIDVPLIEYTELYLKKSGEDIISRLYDFIYRNRRLCLRPEFTASVVRAYLDNLQELPLPVRLYYMGPVFRYEQPQKEKYGQFTQMGIELIGATGAIADGEIISMACQGLDRLGLTEYQTFIGHVGVLNNFLDHLQLDTRLRSFLLTQMETLRIEGKEIVESRLSEIYPAFKKNNFLAEQLDTNTTTKKITDILQNLEENEARTAIFKLLESMNIELTSTRTPEEIVDRLLIKIKHQDQTKELNQALEFMTELSQLKGEPQAIFKEIKKLLSAYGIDDYGLAELQDILKSLEAFNIDKNRISLDLGISRGLQYYTGMVFEIYDSKLGVERKLCGGGRYDDLVVSLGGKQETPATGFSYLMEELRKELTEKAHLSFNNYQFVEALVVGLTREDYSDSVRVAEKLRSLGLRIETDVIGRDIQSNIEYGNQQKISFLIIVNSTEKKGGKVLLQNLDSGEQKKLELHEVVHQVRNIKDNTNC
>NC_008312.1|WP_011610417.1|929568_930585_+|ATP-phosphoribosyltransferase
MTKDQTLRIALPSKGALAKGTMNLLSACGLGVSRPNERQYFGSIPALPQVKVLFQRAADIFTKVEEGSVDLGITGYDVVCEEGQSHDDVIVIWDKLGYGKCKLVLAVPESWVDVSSIEDLAELTLLFRDKGKNLRIATKYHHLTQKWLYEKLIVHFSLVAVQGAMEAAPSMGYADMIADITSTGTTLRENRLKQIEGGTLIESQACLIGNKRLLQENKIKLETTQVFLELLEAQMESKKYVSITANVDGKSLDEIGDRLMYKSQLTGIAGLQGPTIAKVYSREKNSLYAVTIVVKQSMLLPAINHLRNVGGTDMTVSSPSYVFGSQSQIYESFLSKLK
>NC_008312.1|WP_011610418.1|930907_931135_+|ferredoxin-family-protein
MPHTIVTNICEGVADCANACPVACIHSGPGKNNKGTDWYWVDFDSCIDCGICLEVCPVEKAVLAEERPELQQTPE
>NC_008312.1|WP_011610419.1|931528_932113_-|pentapeptide-repeat-containing-protein
MEVERLLERYAAGERNFRDTDLFRANLNNVSLAGVNLFRANLFRANLFRANLIGINLYNSTLIGANLYGANLSGANLSGANLTRANLTGADLSGADLSAADLSGAILSYAHLSYADMSRTNLHKATLIGTNLSGANLSGADLRDIKITKVNVTETKFALAIGLSKDMKLELHQQGARVEDMPKELYASKLLSRI
>NC_008312.1|WP_011610420.1|932939_934169_+|tryptophan-synthase-subunit-beta
MTITPLNPTSTQQPDSLGRFGKFGGKYVPETLMPALLQLETACKKYSQDPTFKQELQQLLRDYVGRPSPLYFAERLTAHYTKPDGTGPQIYLKREDLNHTGAHKINNALGQALLAQRMGKQRIIAETGAGQHGVATATVCARFGLKCVIYMGIHDMERQALNVFRMRLMGAEVRPVEAGTGTLKDATSEAIRDWVTNVETTHYILGSVAGPHPYPMMVRDFHAVIGVETRAQCLEKWNGLPDILMACVGGGSNAMGLFHEFINDPSVRMIGVEAAGKGVDTNKHAATLTLGRVGVLHGAMSYLLQDEEGQIIEPHSISAGLDYPGVGPEHSFLKDSGRVEYYSVTDNEAVAAFQRLSQLEGIIPALETAHAIAYLETLCPQLSGSPRIVFNCSGRGDKDVQTVGKFLEG
>NC_008312.1|WP_011610421.1|934520_935816_+|serine-hydrolase
MILTQKPLLKTIIFAFVYLSLIPFAKALPVAKTPEEIGLSSSKLEAITEELELLVNTRQIAGGVLTVIRNGKVGYRKTVGFRNLETEELIQVNDIFRIASMTKIITGFAAYLLKQDNLIDFNDPVSKYIESYGSLKVLIPGKSGEASDFTTVTAKNQITIQHLLNHTSGLKAGISNSISGNSATIGEAMEKLVNIPLQFEPGSAFLYSNLNSDLLGYLIEVVSEQTLAEFFEARIFQPLEMKDTSFFVREEKLDRLTTVYTPKNNNLKPLVNNADVFKQTYFSGGGGLYSTINDYSRFLQMLLSQGQLISKDGQTVIQVADAKTVEEFLSIKPEDLEINPFFQQLLGGASYRFTNGMAVKSAPSETVASIGAFKWFGAYSTYYFVDPKKELIGILMTQIPFAPFLLQTNLINKFESLIYNSLCNNCQDVEP

Crispr_ID: NC_008312_7

• CRISPR_ID: NC_008312_7
• CRISPR_location: 1110157-1110246
• CRISPR_type: Unclear
• Repeat_type: NA
• Spacer_info: 1 spacers
• Cas_protein_info: Cas14u_CAS-V

Consensus repeat of NC_008312_7

Consensus_repeat	Method
GTTGGGTAGGTTGTATTGGTTGAACTGGAA	CRISPRCasFinder

spacers of NC_008312_7

>7.1|1110187|30|NC_008312|CRISPRCasFinder
TAGGAGATGATTTTTCTGGGTTTAGTTCAA

CRISPR arrays and Neighbor proteins around NC_008312_7

CRISPR arrays

The CRISPR arrays of NC_008312_7

>merge|NC_008312|7|1110157-1110246|CRISPRCasFinder
GTTGGGTAGGTTGTATTGGTTGAACTGGAATAGGAGATGATTTTTCTGGGTTTAGTTCAAGTTGGGTAAGTTGTATTGGTTGAACTGGAA

>NC_008312|7|5|1110157-1110246|CRISPRCasFinder
GTTGGGTAGGTTGTATTGGTTGAACTGGAA	TAGGAGATGATTTTTCTGGGTTTAGTTCAA
GTTGGGTAAGTTGTATTGGTTGAACTGGAA

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_008312.1|WP_011610514.1|1117040_1118570_+|glucose-6-phosphate-dehydrogenase	unknown	unknown	gnl|CDD|235579
NC_008312.1|WP_011610515.1|1118944_1120267_+|glucose-6-phosphate-dehydrogenase-assembly-protein-OpcA	unknown	unknown	gnl|CDD|378404
NC_008312.1|WP_011610504.1|1103769_1104519_+|ATP-binding-cassette-domain-containing-protein	unknown	unknown	gnl|CDD|224058
NC_008312.1|WP_011610511.1|1112417_1112711_+|Dabb-family-protein	unknown	unknown	gnl|CDD|214884
NC_008312.1|WP_011610507.1|1108731_1109067_-|Grx4-family-monothiol-glutaredoxin	unknown	unknown	gnl|CDD|188046
NC_008312.1|WP_011610518.1|1124314_1124830_+|2-amino-4-hydroxy-6--hydroxymethyldihydropteridine-diphosphokinase	unknown	unknown	gnl|CDD|223872
NC_008312.1|WP_011610512.1|1114287_1115352_+|class-1-fructose-bisphosphatase	unknown	unknown	gnl|CDD|236458
NC_008312.1|WP_011610498.1|1094073_1096749_-|Na-Ca-exchanger/integrin-beta4	unknown	unknown	gnl|CDD|273296
NC_008312.1|WP_011610502.1|1102445_1102814_+|DUF1830-domain-containing-protein	unknown	unknown	gnl|CDD|370162
NC_008312.1|WP_011610510.1|1110562_1111246_-|HAD-IA-family-hydrolase	unknown	unknown	gnl|CDD|178407
NC_008312.1|WP_011610516.1|1121931_1122537_-|class-I-SAM-dependent-methyltransferase	unknown	unknown	gnl|CDD|379312
NC_008312.1|WP_011610517.1|1123315_1123678_-|dihydroneopterin-aldolase	unknown	unknown	gnl|CDD|376737
NC_008312.1|WP_011610513.1|1115548_1116691_+|transaldolase	unknown	unknown	gnl|CDD|235117
NC_008312.1|WP_011610503.1|1103207_1103762_+|hypothetical-protein	unknown	unknown	unknown
NC_008312.1|WP_011610505.1|1105111_1105870_-|response-regulator-transcription-factor	unknown	unknown	gnl|CDD|223816
NC_008312.1|WP_011610506.1|1107524_1107776_+|hypothetical-protein	unknown	unknown	unknown
NC_008312.1|WP_044137156.1|1096924_1097611_+|phosphatidate-cytidylyltransferase	unknown	unknown	gnl|CDD|223248
NC_008312.1|WP_081432390.1|1098291_1098867_-|helix-turn-helix-domain-containing-protein	Cas14u_CAS-V	-	gnl|CDD|378838
NC_008312.1|WP_011610521.1|1127117_1127594_+|aspartate-1-decarboxylase	unknown	unknown	gnl|CDD|376751
NC_008312.1|WP_044136349.1|1109389_1109650_-|BolA/IbaG-family-iron-sulfur-metabolism-protein	unknown	unknown	gnl|CDD|223349

HMMScan for Signature genes

Protein	Cas_name	Cas_description	E-value	Identity	Coverage
NC_008312.1|WP_081432390.1|1098291_1098867_-|helix-turn-helix-domain-containing-protein	Cas14u_CAS-V	-	2.8e-21	71.0	0.0

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_008312.1|WP_011610514.1|1117040_1118570_+|glucose-6-phosphate-dehydrogenase	gnl|CDD|235579	PRK05722, PRK05722, glucose-6-phosphate 1-dehydrogenase; Validated.	0
NC_008312.1|WP_011610515.1|1118944_1120267_+|glucose-6-phosphate-dehydrogenase-assembly-protein-OpcA	gnl|CDD|378404	pfam10128, OpcA_G6PD_assem, Glucose-6-phosphate dehydrogenase subunit. Members of this family are found in various prokaryotic OpcA and glucose-6-phosphate dehydrogenase proteins. The exact function of the domain is, as yet, unknown.	1.2927e-97
NC_008312.1|WP_011610504.1|1103769_1104519_+|ATP-binding-cassette-domain-containing-protein	gnl|CDD|224058	COG1135, AbcC, ABC-type metal ion transport system, ATPase component [Inorganic ion transport and metabolism].	1.73792e-63
NC_008312.1|WP_011610511.1|1112417_1112711_+|Dabb-family-protein	gnl|CDD|214884	smart00886, Dabb, Stress responsive A/B Barrel Domain. The function of this domain is unknown, but it is upregulated in response to salt stress in Populus balsamifera (balsam poplar). It is also found at the C-terminus of a fructose 1,6-bisphosphate aldolase from Hydrogenophilus thermoluteolus.It is found in the pA01 plasmid, which encodes genes for molybdopterin uptake and degradation of plant alkaloid nicotine. The structure of one has been solved and the domain forms an alpha-beta barrel dimer. Although there is a clear duplication within the domain it is not obviously detectable in the sequence.	1.64248e-27
NC_008312.1|WP_011610507.1|1108731_1109067_-|Grx4-family-monothiol-glutaredoxin	gnl|CDD|188046	TIGR00365, TIGR00365, monothiol glutaredoxin, Grx4 family. The gene for the member of this glutaredoxin family in E. coli, originally designated ydhD, is now designated grxD. Its protein, Grx4, is a monothiol glutaredoxin similar to Grx5 of yeast, which is involved in iron-sulfur cluster formation. [Energy metabolism, Electron transport].	3.03012e-54
NC_008312.1|WP_011610518.1|1124314_1124830_+|2-amino-4-hydroxy-6--hydroxymethyldihydropteridine-diphosphokinase	gnl|CDD|223872	COG0801, FolK, 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase [Coenzyme metabolism].	4.01026e-66
NC_008312.1|WP_011610512.1|1114287_1115352_+|class-1-fructose-bisphosphatase	gnl|CDD|236458	PRK09293, PRK09293, class 1 fructose-bisphosphatase.	0
NC_008312.1|WP_011610498.1|1094073_1096749_-|Na-Ca-exchanger/integrin-beta4	gnl|CDD|273296	TIGR00845, Sodium/calcium_exchanger_1, sodium/calcium exchanger 1. The Ca2+:Cation Antiporter (CaCA) Family (TC 2.A.19)Proteins of the CaCA family are found ubiquitously, having been identified in animals, plants, yeast, archaea and widely divergent bacteria.All of the characterized animal proteins catalyze Ca2+:Na+ exchange although some also transport K+. The NCX1 plasma membrane protein exchanges 3 Na+ for 1 Ca2+. The E. coli ChaA protein catalyzes Ca2+:H+ antiport but may also catalyze Na+:H+ antiport. All remaining well-characterized members of the family catalyze Ca2+:H+ exchange.This model is specific for the eukaryotic sodium ion/calcium ion exchangers of the Caca family [Transport and binding proteins, Other].	5.53972e-22
NC_008312.1|WP_011610502.1|1102445_1102814_+|DUF1830-domain-containing-protein	gnl|CDD|370162	pfam08865, DUF1830, Domain of unknown function (DUF1830). This family of short proteins is functionally uncharacterized.	2.45668e-38
NC_008312.1|WP_011610510.1|1110562_1111246_-|HAD-IA-family-hydrolase	gnl|CDD|178407	PLN02811, PLN02811, hydrolase.	1.34509e-78
NC_008312.1|WP_011610516.1|1121931_1122537_-|class-I-SAM-dependent-methyltransferase	gnl|CDD|379312	pfam13649, Methyltransf_25, Methyltransferase domain. This family appears to be a methyltransferase domain.	8.79091e-26
NC_008312.1|WP_011610517.1|1123315_1123678_-|dihydroneopterin-aldolase	gnl|CDD|376737	pfam02152, FolB, Dihydroneopterin aldolase. This enzyme EC:4.1.2.25 catalyzes the conversion of 7,8-dihydroneopterin to 6-hydroxymethyl-7,8-dihydropterin in the biosynthetic pathway of tetrahydrofolate.	1.68033e-42
NC_008312.1|WP_011610513.1|1115548_1116691_+|transaldolase	gnl|CDD|235117	PRK03343, PRK03343, transaldolase; Validated.	0
NC_008312.1|WP_011610505.1|1105111_1105870_-|response-regulator-transcription-factor	gnl|CDD|223816	COG0745, OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription].	5.52329e-67
NC_008312.1|WP_044137156.1|1096924_1097611_+|phosphatidate-cytidylyltransferase	gnl|CDD|223248	COG0170, SEC59, Dolichol kinase [Lipid metabolism].	3.83881e-27
NC_008312.1|WP_081432390.1|1098291_1098867_-|helix-turn-helix-domain-containing-protein	gnl|CDD|378838	pfam12323, HTH_OrfB_IS605, Helix-turn-helix domain. This is the N terminal helix-turn-helix domain of Transposase_2 pfam01385.	1.91239e-13
NC_008312.1|WP_011610521.1|1127117_1127594_+|aspartate-1-decarboxylase	gnl|CDD|376751	pfam02261, Asp_decarbox, Aspartate decarboxylase. Decarboxylation of aspartate is the major route of beta-alanine production in bacteria, and is catalyzed by the enzyme aspartate decarboxylase EC:4.1.1.11 which requires a pyruvoyl group for its activity. It is synthesized initially as a proenzyme which is then proteolytically cleaved to an alpha (C-terminal) and beta (N-terminal) subunit and a pyruvoyl group. This family contains both chains of aspartate decarboxylase.	4.15351e-57
NC_008312.1|WP_044136349.1|1109389_1109650_-|BolA/IbaG-family-iron-sulfur-metabolism-protein	gnl|CDD|223349	COG0271, BolA, Stress-induced morphogen (activity unknown) [Signal transduction mechanisms].	3.03829e-26

Protein sequences

>NC_008312.1|WP_044136349.1|1109389_1109650_-|BolA/IbaG-family-iron-sulfur-metabolism-protein
MMNLEQVESMIKAKLPDAQVEVQDLTGGGDHLQAIVVSSEFEGKTLVKQHQMVYAAVKEPMASEAIHALALKTYTPEEWKTAGQTA
>NC_008312.1|WP_011610507.1|1108731_1109067_-|Grx4-family-monothiol-glutaredoxin
MTLTPELKAKIDDLVTKNKIMVFMKGNKLMPQCGFSNNVVQILNILGVTYETCDVLENQDIRTGIKEYSNWPTIPQVYVDGEFLGGSDVMIEMYNNKKEELEQKLAVASAS
>NC_008312.1|WP_011610506.1|1107524_1107776_+|hypothetical-protein
MLTDTLTIRHYQKLTDALVEMWNRGYRYEEMRIYLDGYLASLRISKAIEPFLINRLEEETTRYMYDPSNFEIQLQTQPELDLY
>NC_008312.1|WP_011610505.1|1105111_1105870_-|response-regulator-transcription-factor
MGDACILIVEGNVHLRSLLAWHLQQSKHLVHQSADVDHAKKLIYAHCPSLVILETDLPDGNSFEFCQWLQQQQQCLILMLSSRKTEADIVAGLKSGADDYITKPFGMQEFMARIEALLRRRRSISSTPPISLDYGDLIIDLVHRRVIFKGNLIDLTPQEFNLLYVLAQAEGIPLSRSELLHRGWPDSIDNPRTIDTHVLSLRKKIEIDPRQPSLIQTVRNVGYRFNREILTIDQWNNNYQKSYQQPQKVAPA
>NC_008312.1|WP_011610504.1|1103769_1104519_+|ATP-binding-cassette-domain-containing-protein
MEQQQSQLYLEKVSLTAPVSSLYLLKNISFAVEKGARVAIVGASGAGKTSLLRLLNKLSSPTSGYIYLDNQEYCKIPIVQLRKEVTMVLQESKLLGMPVVEAIAYPLKLRGLKQAEIEQRCEHWIQQLNIPESWLSMSELQLSMGQRQLVAIARAAVIKPKILLLDEPTSALDLGNANRVIQVLAKYAESGVTVIIATTQTHLAQQFCQKLVYLEQGVLIEDAPNSKVNWVELHHHIIQTQAQETEEWS
>NC_008312.1|WP_011610503.1|1103207_1103762_+|hypothetical-protein
MIENQDSETLVFKISPLIKLTLLSLYVALTVPLPFLSQATNAPVPPFILVIGLTIGAIALYGALAERVIVNGQGIQVSYPAWVPDLFRKGWYLPWTEIKALKPRTTGQGGLVYYFLNNSEEGYLLPMRVVGFAKLVRIVETYTGIDTTDVRPLSQPWMYFILLGCTILLLLVDAWTIFNAVAIS
>NC_008312.1|WP_011610502.1|1102445_1102814_+|DUF1830-domain-containing-protein
MAQILDPLPSKSSNPIICCYINATSQIQIAKISNIPNWYFERVVFPGQRLVFESVIGALMEVHTGALASSILSDTIPCDRLQINESPYSSICETKNSVARSVNLSPRLTSPSKSRQVLSRVD
>NC_008312.1|WP_081432390.1|1098291_1098867_-|helix-turn-helix-domain-containing-protein
MLKAKYKYPIEPNIVQIAKLNKLFGCCRYVWNQSLVHCNQLYVYTVKKPSYTDLSKQFITQAKKELTWLKDVADTPLKQCLKDLDQAYQSFFNSCTSKEKGVKVKPPTFKTKKSEQTARFLKYNYKIAEDQIYLTKIGNFKVVGLRELPSIPTSVTIIKDNAGCYFAIFVVEIPVKNLLLSNNLIDVDFGV
>NC_008312.1|WP_044137156.1|1096924_1097611_+|phosphatidate-cytidylyltransferase
MSIISTFPNIWLQVFLVGGWLGIILIFAEALNRFAKVDPEISRKVVHIGTGNVILFAWWLEIPPWIGITAGIISAAIALISYRLPILPSVNSVGRKSLGTFFYAVSIGILIGWFWSIQQPQYAAIGILTMAWGDGFAAIIGQNFGKHPYQVWGMNKSWEGSLGMCLVSYTVCSLILLAVQGNIWQTWIVAIPVALAATALETLSKVGLDNLTVPLGSAALCFFLNQFF
>NC_008312.1|WP_011610498.1|1094073_1096749_-|Na-Ca-exchanger/integrin-beta4
MIDDGCTFPDVTFTVPDVNFMAQVSVEPLGAMGIIEEGWSEVRNNLAEFASSETFERDMLSVFGESTNVDLGRTIIDALVKGEDWPQINVVPAALMNGAAGGFDPLTGEVYLGDSLVEPLSVVGSETREFDLVGVLTEEIAHSIEWKLNLTDTPGDEGEYLAALVNGDELSEGEIARLRGEDDRREILNGTVIVEANSDLTFETQTFPTGDQPLGMAAADFNQDGFQDIVVANIGVANGISIFLGDGKGGVLTAFLSKLEGVVPALVTVGDMNRDGNQDIVTANFRNDSVTVLFGNGKGQFSSSSNFAVGDNPLELAVADVNRDGNLDVVTPNYYSNDVSVLLGNGDGTFMSATNFTTGGSKPEGVVIKDINGDRNPDIMVSNVDSATVAVLPGNGDGTFGLPTSFPAGGKVYGITGKDLNRDGKLDLVLPTLDPDGVSVMLGIGNGFFAFPTNLPVGSLPEHVAIEDLNGDRQLDLVVINRGSDNISVLLGKGKGLFEPAINFGVGEGPNIVVVEDFNNDGKKDIAVTNSEADTISILTNTSKIAVADPNITISDTRITEGNKGRKNAKFTVTLDDASNKTVKVNYATANSSAKAGKDYRKTTGTLTFKPGQTQKKINVPIFGDTIVEKNEKFQLNLSKPKNGKIKDKRGIATIRNDDKNQPLLSIGDAQITEGDQGKKQLKFDVTLNTKVKKRVEVNYATADMTAKKGSDYQQTKGKLIFKPNQKKKTITVPILGDTLNEDDEKFRVNLSRPKNAKLRDKRGVGLIKDNDRGGDQPGDSFETAINLDILTGEQVVSDTIGFTEGIKRDTNDYFRFQTDKEGTFVLVLDDLLKNADVDLYGSEQELINQSKNKGVKPESISTILDPDTYFLRVYPQGSSRTNYRLSVDLL
>NC_008312.1|WP_011610510.1|1110562_1111246_-|HAD-IA-family-hydrolase
MNDFPKITHIIYDLDGLLLDTESIHAQVNQEVTSRYGKTFDKHIKCKITGRKSIDSARKIVELLELPITPENYLQQRNLLTYKRFPQAKPMPGAISLTQHLSQNKIPQAVATSSYREPFNLKTKNHQEWFQLFDYIVVGDDPNIQHGKPAPDIFLIAAQKLEVSPEKCLVFEDSLAGMEAALAARMSVVVVPDPDMDKNLFHSAHQILNSLTEFQPHLWQLPSFLST
>NC_008312.1|WP_011610511.1|1112417_1112711_+|Dabb-family-protein
MIVHIVLFKWNSDTSTETIASVMSALRGMKGKVPEIIDLSCGDNFSELSQGFQNGLVVQVKDKAALDAYAKNSIHQQIIQTLIKPILADKITIDYEV
>NC_008312.1|WP_011610512.1|1114287_1115352_+|class-1-fructose-bisphosphatase
MVNTQAREDLHIRLEETQLLDRDCTTLSRHVLQQLHFSPDAQDISSLMNRIGLAGKLIARRLTRAGLLEDTLGFTGTVNVQGESVKKMDIYANDVFISVFKQSGLVCRLASEEMEKPYYIPENCPIGRYTLLYDPLDGSSNLDTNLNVGSIFSVRQQEGNDENGLAQDLLQNGHKQIAAGYILYGPSTMLVYSIGQGVHAFTLDPSLGEFILVNENIKIPEHGPVYSVNEGNFWQWDDSMRDYIRYVHRHEGYTARYGGALVGDFHRILYQGGVFLYPGTVKKPEGKLRLLYESAPMGYLVEQAGGRASTGTEEILDVVADQLHQRTPLIIGSKEDVALVESFIKEQKRISNQG
>NC_008312.1|WP_011610513.1|1115548_1116691_+|transaldolase
MVTNHLLEIENLGQSIWMDNLSRNIIESGELKSMIGKKGIRGITSNPAIFEKAIAGNAIYDADIEAGIKASKSVIEIYESLVFKDIRDACDIFMPVYEETKGLDGYISIEVPPTIAKDTESTISEAIRYYTAIGRENLMIKIPGTPEGLPAVTRVISEGINVNVTLLFSVESYINTAWAYIEGLEARAAKGEDIDKIASVASFFLSRIDSNIDGLIDEKLKKVTDETVKAKLEAVKGKVAIANAKIAYQEYKKIIQSDRWKALSAKGAKEQRLLWASTSTKNPAYSDVMYVDELIGPNTVNTLPPPTIDACADHCDVDNRVETNIEVTKEVMENLKDPDININIDQVMEQLLVEGIDKFIKPFTSLINSLEEKVKKLTPV
>NC_008312.1|WP_011610514.1|1117040_1118570_+|glucose-6-phosphate-dehydrogenase
MVAVLENPLRVGLQQDRVPEPQIMIIFGASGDLTQRKLVPALYQMKLERRLPPELTIVGVARREWSHDYFREQMKIGVEEFGGGLQSEELWNDFAKGIFYCPGNIDQPEDYQRLKKLLSQLDEERGTRGNRVFYLSVAPRYFGEATQQLGAAGMLVDPKKQRLVIEKPFGRDLSSAQVLNKIVRQVCPEEQIYRIDHYLGKETVQNLMVFRFANAIFEPLWNRQFVDNVQITVAETVGLEGRAGYYETSGALRDMVQNHLMQLFSLTAMEPPNSLDADSIRNEKVKVVQATRLANLERLEYSAIRGQYTQGWMKGKSVPAYREEGGANPNSTTPTYAALKLNIDNWRWKGVPFYLRTGKRMPKKVSEIAIQFKEVPFLMFQSAAKQANPNVLALRIQPNEGVSMRFEVKTPGSSLRTRSVDMDFRYDTAFGKPSTDAYSRLLVDCMLGDQTLFTRGDEVEASWRALTPILSIWDAPAPPEVIPLYEAGTWGPVEAELLLNQDGRRWRRL
>NC_008312.1|WP_011610515.1|1118944_1120267_+|glucose-6-phosphate-dehydrogenase-assembly-protein-OpcA
MSTTLVALQQPKDISLGEIEAELNKIWLSQGGGKATPIATRAATFSMVIYEPEEFQQLLAGLGFYKGEIDGVNGIVAREAIKEAQKAYNLPITGRVDSETLAKLRSEWATKSLENRQFPNIDVRGSSVSEVIAAQNPCRVITLCPTFGEDTGVTAQVSAYCPVQKKQSSLICCEYITLHGTREALERVSDVVTSLMIPDLPKFVWWKATPNREQELFRRLCKTSNCIILDSSYFSDPESEFLKMLELIENKTYIADLNWHRLSAWQELTAATFDPPERRASLGEIDTITLDYEKGNVSQALMFLGWFASRLDWQPTTYTETGGDYDIIHIKFIGPNNKEILAELAAISTTDYGEIPGDLVGLRLDSSNPSADCCTILCSETTGCMRLEAGGSAQSCRTEQVSALSDQKAEYLMAQQLQRWGREVLYEDSLAVTVEILKLR
>NC_008312.1|WP_011610516.1|1121931_1122537_-|class-I-SAM-dependent-methyltransferase
MTNKTSVKQTFFDLWAPSYDWLFPSIVYQAIHKRLLEYVDLSNSANVLDLGCGTGKLLHRLAVNFPTLQGNGLDLSPEMISQANSRNCYPQRLKFLLGNAEEIPFENDVFDAVFNTISFLHYPHPQQVFNEVNRVLRHGGYFYLVDSYFKWQDELQYLSISPGGLKLYSPTAREKFGKEAGLNLQANYYLLGSVLLTIFTK
>NC_008312.1|WP_011610517.1|1123315_1123678_-|dihydroneopterin-aldolase
MDSISITGIRCYGYIGFFPEEKVLGQWFEVDLTLGLDLTAASKSDALEDTVDYGSIVNTVQKLVKQSKSALLEKVANTIATDILQQRLVQNVKVRLTKLAAPIPDFGGKVTIEITRVKEK
>NC_008312.1|WP_011610518.1|1124314_1124830_+|2-amino-4-hydroxy-6--hydroxymethyldihydropteridine-diphosphokinase
MSNPTNLKNSPKNQGHVAIGMGSNLGESLDTLKNAIQTLDEIAGIKLITYSSWYRTKPIGPPQPDYINGCALLKVELTPHKLLEVLLDVEQKFKRVRLEHWGPRTLDLDLILYDDLILDTPNLQIPHPRMKERAFVLVPLAEIAPNWIDPVSGKAIALLQEEVECSGISKL
>NC_008312.1|WP_011610521.1|1127117_1127594_+|aspartate-1-decarboxylase
MTTIKLMHAKLHRVRVTDAKPDYVGSVTIDSDLLEKVGILPLEEVQIVNLNNGQRWLTYVLPGQAGSGMVCPNGGAALLCKKDDILIIWANEQCDRAEVLENGHKAKIFVADENNHCREFLYQILNPNQGSVEFHSLPVIPEGKTSEYLQQMIETNKI

Crispr_ID: NC_008312_8

• CRISPR_ID: NC_008312_8
• CRISPR_location: 1276978-1277054
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NC_008312_8

Consensus_repeat	Method
CAAGGTGATGATCATCTTATTGG	CRISPRCasFinder

spacers of NC_008312_8

>8.1|1277001|31|NC_008312|CRISPRCasFinder
CCAAGCGGGGAAAGACAAGTTAGAAGGTTCA

CRISPR arrays and Neighbor proteins around NC_008312_8

CRISPR arrays

The CRISPR arrays of NC_008312_8

>merge|NC_008312|8|1276978-1277054|CRISPRCasFinder
CAAGGTGATGATCATCTTATTGGCCAAGCGGGGAAAGACAAGTTAGAAGGTTCAGAAGGTGATGATCATCTTATTGG

>NC_008312|8|6|1276978-1277054|CRISPRCasFinder
CAAGGTGATGATCATCTTATTGG	CCAAGCGGGGAAAGACAAGTTAGAAGGTTCA
GAAGGTGATGATCATCTTATTGG

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_008312.1|WP_155994286.1|1263815_1263953_+|hypothetical-protein	unknown	unknown	unknown
NC_008312.1|WP_011610614.1|1281380_1282022_+|TenA-family-protein	unknown	unknown	gnl|CDD|381703
NC_008312.1|WP_011610620.1|1287238_1289170_+|mechanosensitive-ion-channel	unknown	unknown	gnl|CDD|225803
NC_008312.1|WP_071820739.1|1271189_1271273_+|DUF2887-domain-containing-protein	unknown	unknown	gnl|CDD|371375
NC_008312.1|WP_011610606.1|1264285_1265392_+|hydrogenase-expression/formation-protein-HypE	unknown	unknown	gnl|CDD|273984
NC_008312.1|WP_155994288.1|1289413_1289590_+|hypothetical-protein	unknown	unknown	unknown
NC_008312.1|WP_011610616.1|1282671_1283964_-|hypothetical-protein	unknown	unknown	gnl|CDD|224276
NC_008312.1|WP_011610617.1|1284062_1284626_+|peptide-deformylase	unknown	unknown	gnl|CDD|234668
NC_008312.1|WP_011610607.1|1265647_1265992_+|hydrogenase-maturation-nickel-metallochaperone-HypA	unknown	unknown	gnl|CDD|376468
NC_008312.1|WP_011610605.1|1261719_1262853_+|hydrogenase-formation-protein-HypD	unknown	unknown	gnl|CDD|237892
NC_008312.1|WP_155994290.1|1289780_1291265_-|serine/threonine-protein-kinase	unknown	unknown	gnl|CDD|373105
NC_008312.1|WP_011610608.1|1266309_1267314_-|galactose/methyl-galactoside-ABC-transporter-permease-MglC	unknown	unknown	gnl|CDD|181892
NC_008312.1|WP_011610613.1|1279952_1280891_-|glycosyltransferase-family-2-protein	unknown	unknown	gnl|CDD|133030
NC_008312.1|WP_011610618.1|1284894_1285095_+|hypothetical-protein	unknown	unknown	unknown
NC_008312.1|WP_011610619.1|1286185_1287082_-|hypothetical-protein	unknown	unknown	unknown
NC_008312.1|WP_011610611.1|1271552_1272392_+|hydrogenase-nickel-incorporation-protein-HypB	unknown	unknown	gnl|CDD|182479
NC_008312.1|WP_011610609.1|1267523_1269053_-|ATP-binding-cassette-domain-containing-protein	unknown	unknown	gnl|CDD|182880
NC_008312.1|WP_011610622.1|1291959_1294113_+|hypothetical-protein	unknown	unknown	gnl|CDD|132835
NC_008312.1|WP_011610610.1|1269286_1270315_-|galactose/glucose-ABC-transporter-substrate-binding-protein-MglB	unknown	unknown	gnl|CDD|380481
NC_008312.1|WP_011610604.1|1261082_1261331_+|HypC/HybG/HupF-family-hydrogenase-formation-chaperone	unknown	unknown	gnl|CDD|376549

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_008312.1|WP_155994290.1|1289780_1291265_-|serine/threonine-protein-kinase	gnl|CDD|373105	pfam14516, AAA_35, AAA-like domain. This family of proteins are part of the AAA superfamily.	1.12817e-166
NC_008312.1|WP_011610614.1|1281380_1282022_+|TenA-family-protein	gnl|CDD|381703	cd19368, TenA_C_AtTH2-like, TenA_C family similar to the N-terminal TenA_C domain of Arabidopsis thaliana thiamine requiring 2. This TenA family belongs to the TenA_C class as it has a conserved active site Cys residue; the double Glu residues identified in the active site of TenA_E from the archaeon Pyrococcus furiosus is conserved in this family. TenA_C proteins (EC 3.5.99.2) catalyze the hydrolysis of the thiamin breakdown product 4-amino-5-amino-methyl-2-methylpyrimidine (amino-HMP) to 4-amino-5-hydroxymethyl-2-methylpyrimidine (HMP) in a thiamin salvage pathway. Arabidopsis thaliana TH2 is an orphan enzyme thiamin monophosphate phosphatase which has a haloacid dehalogenase (HAD) family domain fused to its TenA_C domain, it's TenA_C domain has thiamin salvage hydrolase activity against amino-HMP. This family includes mostly uncharacterized single-domain TenA_C- like proteins; some however have additional domains such as a HAD family domain or a kinase domain It has also been suggested that TenA proteins act as transcriptional regulators based on changes in gene-expression patterns when TenA is overexpressed in Bacillus subtilis, however this effect may be indirect.	1.24133e-92
NC_008312.1|WP_011610620.1|1287238_1289170_+|mechanosensitive-ion-channel	gnl|CDD|225803	COG3264, COG3264, Small-conductance mechanosensitive channel [Cell envelope biogenesis, outer membrane].	3.3352e-58
NC_008312.1|WP_071820739.1|1271189_1271273_+|DUF2887-domain-containing-protein	gnl|CDD|371375	pfam11103, DUF2887, Protein of unknown function (DUF2887). This bacterial family of proteins has no known function. These proteins may be distantly related to the PD(D/E)XK superfamily.	4.87497e-06
NC_008312.1|WP_011610606.1|1264285_1265392_+|hydrogenase-expression/formation-protein-HypE	gnl|CDD|273984	TIGR02124, Hydrogenase_expression/formation_protein_HypE, hydrogenase expression/formation protein HypE. This family contains HypE (or HupE), a protein required for expression of catalytically active hydrogenase in many systems. It appears to be an accessory protein involved in maturation rather than a regulatory protein involved in expression. HypE shows considerable homology to the thiamine-monophosphate kinase ThiL (TIGR01379) and other enzymes.	8.87123e-175
NC_008312.1|WP_011610616.1|1282671_1283964_-|hypothetical-protein	gnl|CDD|224276	COG1357, COG1357, Pentapeptide repeats containing protein [Function unknown].	3.15955e-20
NC_008312.1|WP_011610617.1|1284062_1284626_+|peptide-deformylase	gnl|CDD|234668	PRK00150, def, peptide deformylase; Reviewed.	3.47531e-75
NC_008312.1|WP_011610607.1|1265647_1265992_+|hydrogenase-maturation-nickel-metallochaperone-HypA	gnl|CDD|376468	pfam01155, HypA, Hydrogenase/urease nickel incorporation, metallochaperone, hypA. HypA is a metallochaperone that binds nickel to bring it safely to its target. The targets for Hypa are the nickel-containing enzymes [Ni,Fe]-hydrogenase and urease. The nickel coordinates with four nitrogens within the protein. The four conserved cysteines towards the C-terminus bind one zinc moiety probably to stabilize the protein fold.	2.10029e-41
NC_008312.1|WP_011610605.1|1261719_1262853_+|hydrogenase-formation-protein-HypD	gnl|CDD|237892	PRK15062, PRK15062, hydrogenase isoenzymes formation protein HypD; Provisional.	0
NC_008312.1|WP_011610608.1|1266309_1267314_-|galactose/methyl-galactoside-ABC-transporter-permease-MglC	gnl|CDD|181892	PRK09478, mglC, galactose/methyl galactoside ABC transporter permease MglC.	7.17598e-167
NC_008312.1|WP_011610613.1|1279952_1280891_-|glycosyltransferase-family-2-protein	gnl|CDD|133030	cd04187, DPM1_like_bac, Bacterial DPM1_like enzymes are related to eukaryotic DPM1. A family of bacterial enzymes related to eukaryotic DPM1; Although the mechanism of eukaryotic enzyme is well studied, the mechanism of the bacterial enzymes is not well understood. The eukaryotic DPM1 is the catalytic subunit of eukaryotic Dolichol-phosphate mannose (DPM) synthase. DPM synthase is required for synthesis of the glycosylphosphatidylinositol (GPI) anchor, N-glycan precursor, protein O-mannose, and C-mannose. The enzyme has three subunits, DPM1, DPM2 and DPM3. DPM is synthesized from dolichol phosphate and GDP-Man on the cytosolic surface of the ER membrane by DPM synthase and then is flipped onto the luminal side and used as a donor substrate. This protein family belongs to Glycosyltransferase 2 superfamily.	6.72775e-96
NC_008312.1|WP_011610611.1|1271552_1272392_+|hydrogenase-nickel-incorporation-protein-HypB	gnl|CDD|182479	PRK10463, PRK10463, hydrogenase nickel incorporation protein HypB; Provisional.	1.20243e-117
NC_008312.1|WP_011610609.1|1267523_1269053_-|ATP-binding-cassette-domain-containing-protein	gnl|CDD|182880	PRK10982, PRK10982, galactose/methyl galaxtoside transporter ATP-binding protein; Provisional.	0
NC_008312.1|WP_011610622.1|1291959_1294113_+|hypothetical-protein	gnl|CDD|132835	cd00147, cPLA2_like, Cytosolic phospholipase A2, catalytic domain; hydrolyses arachidonyl phospholipids. Catalytic domain of cytosolic phospholipase A2 (PLA2; EC 3.1.1.4) hydrolyzes the sn-2-acyl ester bond of phospholipids to release arachidonic acid. At the active site, cPLA2 contains a serine nucleophile through which the catalytic mechanism is initiated. The active site is partially covered by a solvent-accessible flexible lid. cPLA2 displays interfacial activation as it exists in both "closed lid" and "open lid" forms. Movement of the cPLA2 lid possibly exposes a greater hydrophobic surface and the active site. cPLA2 belongs to the alpha-beta hydrolase family which is identified by a characteristic nucleophile elbow with a consensus sequence of Sm-X-Nu-Sm (Sm = small residue, X = any residue and Nu = nucleophile). Calcium is required for cPLA2 to bind with membranes or phospholipids. Group IV cPLA2 includes six intercellular enzymes: cPLA2alpha, cPLA2beta, cPLA2gamma, cPLA2delta, cPLA2epsilon, and cPLA2zeta.	0.00973278
NC_008312.1|WP_011610610.1|1269286_1270315_-|galactose/glucose-ABC-transporter-substrate-binding-protein-MglB	gnl|CDD|380481	cd01539, PBP1_GGBP, periplasmic glucose/galactose-binding protein (GGBP) involved in chemotaxis towards, and active transport of, glucose and galactose in various bacterial species. Periplasmic glucose/galactose-binding protein (GGBP) involved in chemotaxis towards, and active transport of, glucose and galactose in various bacterial species. GGBP is a member of the pentose/hexose sugar-binding protein family of the type 1 periplasmic binding protein superfamily which consists of two alpha/beta globular domains connected by a three-stranded hinge. This Venus flytrap-like domain undergoes transition from an open to a closed conformational state upon ligand binding. Moreover, the periplasmic GGBP is homologous to the ligand-binding domain of eukaryotic receptors such as glutamate receptor (GluR) and DNA-binding transcriptional repressors such as LacI and GalR.	1.596e-142
NC_008312.1|WP_011610604.1|1261082_1261331_+|HypC/HybG/HupF-family-hydrogenase-formation-chaperone	gnl|CDD|376549	pfam01455, HupF_HypC, HupF/HypC family.	1.39917e-26

Protein sequences

>NC_008312.1|WP_011610611.1|1271552_1272392_+|hydrogenase-nickel-incorporation-protein-HypB
MCVTCGCSGNNEATITNSQTGEKIAISNHHPHTHTLPDGTVITHTHSDNYTPKNHNHKTAEDHAKIHKNTISLEKEILQKNDLIAAQNRGWFKGRNILALNLVSSPGSGKTTLLSRTINDLKSDLTFSVIEGDQETINDAEKIRKTGCKVVQINTGKGCHLEAAMVEKGYTELNPPLNSVLMIENVGNLVCPALFDLGESCKVAILSVTEGEDKPIKYPYMFRESQVMILTKIDLLPYLQFDLNRCVEYAKQVNPQIRIFQVSAFTGEGLNKWYDWLKS
>NC_008312.1|WP_071820739.1|1271189_1271273_+|DUF2887-domain-containing-protein
MNQPNTDSQSYEFTSNEVKQLSFRLDS
>NC_008312.1|WP_011610610.1|1269286_1270315_-|galactose/glucose-ABC-transporter-substrate-binding-protein-MglB
MKKSLFIASILASLLFIGCTANTSNNKENLIKIGVTIYKYDDNFMSYVRRYIESSANAKARLFINDSQNNQAKQLEQIDTMIAKGVKALAINLVDPKSAITVIAKAKKANLPVIFFNKEPELELLNSYEKSWYVGTNSQESGIIQGTIITNLWNKNKEQWDLNQDGKIQYVLLKGEPGHPDAEARTKYVIDEVKKAGIEVEKLAIDTAMWDATKAANKMDVWISKYGNKIELVIANNDAMALGALSSLEKAGYFKDNKLVPIVGVDAIPEVLIKIREGKIVGTVLNDAKNQGKATFDLAFNAALGKDILADTQWKLDVNKAVLVPYVSITKDNLGVAEDAYN
>NC_008312.1|WP_011610609.1|1267523_1269053_-|ATP-binding-cassette-domain-containing-protein
MVGEEFKTKYALEMTNISKTFSGVQALSGAILKVRPGTVHSLVGENGAGKSTLMKCLFGIYKLDAGEIYLSGKRVKIFSPQQALRYGVSMVHQELNQVRQMNIMDNIWLGRYPIKGIFIDTIKCFKDTKNLFEKLSIELNPKRNVSSLSISEMQLVEIAKAVSSNSKIIVMDEPTSSLTVTEVEHLFSIINQLKNQNVGVIYISHKIEEVLNISDEITIMRDGFCIATKPSQDLTKSEIIEMMVNRKLSSLFPHKTCQLGKVILEVKNLTAYTQPSIKDINFELKAGEILGIAGLVGAKRTDILEGIFGIRKVSSGEILLEGKKIDNSRINKVISQGFALVTEERRSTGIFDSLSVSFNATIANINYYVNSWGLLSEKKIRQHTQEIIDSMGVKTPSQKTLIGKLSGGNQQKVIIGRWLLTKPKILMLDEPTRGIDVGAKYEIYKLINDLANEGMGIIMVSSEMSELLGVTDRILVMSNGKVAGIVESKKMTQNNRIQEEIMGLSGLYL
>NC_008312.1|WP_011610608.1|1266309_1267314_-|galactose/methyl-galactoside-ABC-transporter-permease-MglC
MIKQIINFALNNAIYLVLILLLIVITIISPDFLTVNNFRLILTQASTRIIIALGVGGVLITQGTDLSAGRIVGVGAVLSASLLQGADYPYRMYPNLMELPLIIPMLFTLIICAFFGFINGVVVGMFKVPPFIATLGTMIIIYGLNSIYFDRPPLGAQPVGGLAENFTTFVQGDLILGSFEIPYLIIYAVIVIGVIWVLWNQTILGRNMYAIGGNIEAATVSGVSVIKYLLIVYTLAGLLYGFAGILEAGRVGSATNNTGNMYELDAIAACVVGGVSTSGGIGTVSGVVTGVLIFQIINYGLVFIELSPYLQFIVKGLIIVSAVAIDIRKYVRQS
>NC_008312.1|WP_011610607.1|1265647_1265992_+|hydrogenase-maturation-nickel-metallochaperone-HypA
MHELGITQNIVAIVAENANNRLIKRVTLEIGELSAIMPNAIEFCFDVCTQGTVLEGATLEIIKIPGLGKCRQCATEIPLEQPFGICHVCNSVELDIIQGQELKIKEMEVEELSV
>NC_008312.1|WP_011610606.1|1264285_1265392_+|hydrogenase-expression/formation-protein-HypE
MTNSLSNEPKQHSLFKKIERARRRPTKVRDTNITLAYGSGGKAMRDLIEDIFVSNFDNPILSQLEDQATFDLATFTAQGDRLAFTTDSYVVDPIFFPGGNIGELAVNGTVNDLAVSGAKPLYLSCGMIIEEGFPVDSLRKIAKSMKVAADVAGVKIVTGDTKVVPQGAADKLFINTAGVGVVRSGISISAQNIQPGDTVIVNGYLGDHGAAITVARGDLALATEVKSDTQALNGLVDIILDVCLEVRAMRDATRGGVATVLNEFAMSSEVGIRLFESSLPVREEVQGVCEILGLDPLYFANEGKLVTVVPREKGEAVLAAMKSHPAGIDAAIVGEVIASPPGILFLQTTFGTERIVDMLVGEQLPRIC
>NC_008312.1|WP_155994286.1|1263815_1263953_+|hypothetical-protein
MDRKLQKLFSNMGKIPPQVNREYVNCLVEVLLTNGNSVAWYAEGI
>NC_008312.1|WP_011610605.1|1261719_1262853_+|hydrogenase-formation-protein-HypD
MKYVKEFRDPDKAQGLVREIAQLSQKLGYTTEHPLKIMEVCGGHTHSIFKYGIQEALPNNIELIHGPGCPVCIMPRGRLDDAIALAEKPNVIFTTFGDGMRVPGSQKSLLQAKAQGADIRMVYSPLDSLKIAKENPDKEIIFFGLGFETTAPSAALTILQAEAEGVKNFSIFSNHVLVVPALEALLSNPDLELQGFVGPGHVSMVIGTQVYHIISEKYQKPVVVSGFEPLDILQSIWMLLQQILEGRCEVENQYSRIVKEEGNRVALEAMKRVFEVRDTFEWRGLGEIPESGLKITDAYSCFDAEAKFCLPNKKVADAKACQCGEILKGVLKPWECKVFGTACTPENPIGTCMVSSEGACAAYYKYGRLFKKEKVKV
>NC_008312.1|WP_011610604.1|1261082_1261331_+|HypC/HybG/HupF-family-hydrogenase-formation-chaperone
MCLGIPGQIVEITDIVKKLAMVSISGVKREVNIACIIDEEHPIESCVGDWVLVHVGFAMNRLDEEEATETLKLLQEVAAVMN
>NC_008312.1|WP_011610613.1|1279952_1280891_-|glycosyltransferase-family-2-protein
MKYSLVIPIYNEEKNLPELYRRLSAVMERIDGDVELILINDGSRDRSLEIIREFHRKDPRICYLSFARNFGHQIAVTAGLNFARGEVIVVLDGDLQDPPELIPDLIEKWRQGYQVVYAQRTKRHQESWFKRLPAFIYYRVLKRLADVEIPIDTGDFCLMDRCVVDLLNKMPETNRYIRGLRAWVGFRQTAIKFEREPRFAGNIQYTFAKSLTLAINGLVSFSKVPLRLSTYVGLFAACVALLMACLVLYWRIFYPNSPLTGLAIIMMAIFFLGAVQLVSIGILGEYIGRIYEEVKGRPLYTLSEVVGFEDRN
>NC_008312.1|WP_011610614.1|1281380_1282022_+|TenA-family-protein
MISKNLWKSNQDLATACLCHPFVQGIANGTLPQKSFAYYVGQDAFFLKAFARAYSIAAAKSDEWKTFELFHTLAGGVKEELELHQTYAAKWGVNLENITPGFATRRYTDFLLATAWGNNIGAIATAMTPCMRLYAFLGQQLATPKIPEHQYSQWIRTYSTQEFLQLVQNLEKVTDRYAENIQETESIYCYAMVCERDFFQAAWEMGKGAYRIH
>NC_008312.1|WP_011610616.1|1282671_1283964_-|hypothetical-protein
MNNYSNFSPSNNPNSHSTLESPNGTPEAITSVKKLNFIDNEIEQMLPTPATPNTLVEHQKSEGPKNPVASIVTLVAIALMILGLAIDNVLLGYTSAIIVILSSVKMIWPSWGKVWKTLIPSVWRNLIIACFGLLAAIVGLLMLSGANQQPGSRNIHINWDAIGAVGELIGALGQILIAIIAVYVAWRQYVISKDLTIQQNRITQQQTIDAYFQGVSDLAMDEKGFLEDWPQERAIAEGRTAAIIKSVDEEGKAKILRFLSQSRLVTPIKRDRLLGRPIFDGQGGYAEDREHGTRVIDLGVMLAGADLKNTDLRWTELSDANLVRANLSGCDLVKANFSRTILYEASLVGADLRGVRFFYGTAEYATPRSRTHIPNYQTGAYTGAVVENVDFTEVKRLSDEQHYYCCAWSGERSRKTIPNGCGGIPNKLGR
>NC_008312.1|WP_011610617.1|1284062_1284626_+|peptide-deformylase
MDSEIIVNKEKLENSPLEIYYLGDRSLRQSAKRVAKVDSDMRKLVREMLQTMYTADGIGLAAPQVNVQKQVIVIDCEPTNSATPPLVLINPTIKKYSNDICLFQEGCLSIPGVYLDVQRPSEIEVAYKDENGRPQTLQAQELLSRAIQHEMDHLQGILFVDRVENKLALNEELAKYKFSAKDVRSIA
>NC_008312.1|WP_011610618.1|1284894_1285095_+|hypothetical-protein
MVGTPKSTLFLGGSCVAAIAAVGSIFELSSGSPELGTAVTGIVLSLSIPLAALLFYLAIQDAKANQ
>NC_008312.1|WP_011610619.1|1286185_1287082_-|hypothetical-protein
MKKLPLYVTISIIFGCSNFSTTENQLYLPITSPTPTFIECPKKPVIRLDKTETKSLSLTESLIKISDSVNSEKHIGYKFYARTGKDFHYRITSNVCIWIFAPDTKLLQRRELIIAAQKDSPLIGEQMLIDLPLTGEYIVQVSSPNEPAEFNLEMSLGYLEKSESSMVSSKNTTLTSQSISKLENTQTKNSAEEAIKNYYSNLNEGKYQQAWNQLSASFQNNQRLHPEGYNSYYKWWSGISNVLTQDIQKINISTGTATVNVQVKYTKKSGENITQSLKLFLVWDSANKNWSIDVVTLN
>NC_008312.1|WP_011610620.1|1287238_1289170_+|mechanosensitive-ion-channel
MARLQKYKLRFALVVSISLLLVFLLFPVQAKDTTSVKVPVVLDGRELLEVGALGKLTAQERAKFTTSILKSALADSIERGTPPDVKVVRSNQNVLLKVDSRPLVEIAEDTFNSMYSEMQVQMWQKQLQQGLEKSWRERTPAYTRWAVKMLTIAFLITLLLQGGLVLLFRYVLRQKIKNPHRRGGSLRLLGLVLLQIAIWAIFINYGVQLFPITRGWFYEIFQLLDNTFNARMFQLGEETISLNRILTIALTIAALWIGVGWLVSILKSRLLPLTGAETSHQDTIAFFLQYGLLSVGALLILNAGGVDFQSLALLLGALGVGIGFGLQNIVKDFICGLILIVARPIKVGELVQVGNFQGLVQRIGARTTDISNVERYIITIPNSRFIEGEVLNWNRSGITRVKAYVKIPYGTDIDFVYKVLLAAAQVEHPDILRHPPPKVKFREYVENGLQFRMVAFIRDPLKQLEVRTHLYKQIEKYLRKYGVEVARRRQDIHLKDLDPEIYGGERSQTSAEDRLLSQEMLSIEPPSIKEEYDWEAISTAMGGENGVSIKDRRFHFKIFKNVFLGSEAVEWLMINERATREEAILMGELMLQQGIIHHVLDEHNFKDEPLFYRFYNHEVEANINTNANGSEHGIDSKLQDDAE
>NC_008312.1|WP_155994288.1|1289413_1289590_+|hypothetical-protein
MNKLIILVRGGSRLNFIDPNFFLVFLELPKKAIAHKAKTIFRTNSVSSLSLILTKPEQ
>NC_008312.1|WP_155994290.1|1289780_1291265_-|serine/threonine-protein-kinase
MTTMTKSIRRRGVILSSQGCRKLIKTKSDLEVQQNQRYTLESLSEKIGLTPNTISKVFTCSSGVDKRTLKCCFQAFNLTLTREDYVYLQSNQENLEEINPIPLAKTCFFPKLTYSSSLHLLPYQNNSPQGKNMVKPQQKLQSHLPKTPGGQMPIDSVFYIDRPIIQSLCNKSIQQPGTLLNICAPKQMGKTSLMSRIIAFAKSLGYQTFYLNLQLVDLKILQNLESFLQWFCARVTQELKLSQAHSNQAIYHEQITAFWQNSLGNKSIATDYLNDIILTQSDRPLVIAIDELNQLFTYPDIACEFLQLLRAWSGRTQAGETESHPWQKLRLLTIYSTEIMMPSSINPSLLNTGTLINLPEFTPAQVQELAQRYQQEITESQIQQLITILGGHPYRLQLAFYSLYQQTITLEAILENSDSLTVLYAEHLQQQWWNLQHYHELLPIFTKIVNNPKPIKIQLSLGYQLQKMGLVRLKGNLASLSCELFRPFFMGALN
>NC_008312.1|WP_011610622.1|1291959_1294113_+|hypothetical-protein
MDKNTPIYIAISGGGFHSHTAMSAWISGILHHSELESLEQIFENVRGISANSGGSWFMSHLGYSNAFVKSLLEDSQSEKSTWSSSGYLGKMGESFFSKDDEKASDMSIFSPVKIETFLAKYIDLFNVYAEIFPNGNRRWHQFVTTKVYEPLEKLGNAENGFETMKGKKLSETNDRLPWFREKDFVIAAGLLNSKVVLHATGGLGSTNQVYSVNSADGSKLRNFVPMCLSGVANGRKAAPVFVSGPQEVIYSEESKWRIPLTANHPQNLNLLDATIASSSAIAFLASESSIGEMIPSLNEGLTFEWISYQEADFAPPIRFGNDRIEILKTLERASYDEFANQKMARVADGGYLDNTSVVFQLRHMKENGDLKDGFHLVLFVNGSDEGVKYHGYEMNVGIATLFGHDGLSEAHRAERVKKGEKIQPEEGSIWNSPFSDLCMEIPSPHVFETEPLENNTAISMWNWKSKDEKISLQARKIPVTTVENKTYGISAGVMGTIYIFEVTQPESFPMPTHRDILETYEYLFETIRNEACAKNQALSHLKEALALKINIPTDPHPIPEIVKKNDNIVLQWNSDGSYLSSSDSGFRYYLATLNRLKSYAKIHKFDNMYSDNLHHGDLVRIKTTEQFKGIWNQRKLLGAFANSYELYYWSDSGDKTNWIIEKAAGTAQETEIAYGEKVYIKNKSYNQYLVFAKDGYLTTKKIQNPGDEHTWVIHRPE

Crispr_ID: NC_008312_9

• CRISPR_ID: NC_008312_9
• CRISPR_location: 1311829-1311915
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers
• Cas_protein_info: PD-DExK

Consensus repeat of NC_008312_9

Consensus_repeat	Method
TTATTGCTGAGAAAAATAATAATATAAATA	CRISPRCasFinder

spacers of NC_008312_9

>9.1|1311859|27|NC_008312|CRISPRCasFinder
AGGAGTTGACAGAATTGACGAAATTGT

CRISPR arrays and Neighbor proteins around NC_008312_9

CRISPR arrays

The CRISPR arrays of NC_008312_9

>merge|NC_008312|9|1311829-1311915|CRISPRCasFinder
TTATTGCTGAGAAAAATAATAATATAAATAAGGAGTTGACAGAATTGACGAAATTGTTTATTACTGAGAAAAATAATAATATAAATA

>NC_008312|9|7|1311829-1311915|CRISPRCasFinder
TTATTGCTGAGAAAAATAATAATATAAATA	AGGAGTTGACAGAATTGACGAAATTGT
TTATTACTGAGAAAAATAATAATATAAATA

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_008312.1|WP_011610627.1|1299864_1300983_-|hypothetical-protein	unknown	unknown	unknown
NC_008312.1|WP_044137169.1|1317055_1317484_+|hypothetical-protein	unknown	unknown	unknown
NC_008312.1|WP_011610623.1|1294563_1295925_+|membrane-attack-complex-component/perforin/complement-C9	unknown	unknown	gnl|CDD|366826
NC_008312.1|WP_011610626.1|1299129_1299747_-|hypothetical-protein	PD-DExK	mkCas0061_PD-DExK_CAS-I:CAS-III	unknown
NC_008312.1|WP_011610637.1|1318856_1319852_-|multicopper-oxidase-domain-containing-protein	unknown	unknown	gnl|CDD|259910
NC_008312.1|WP_081432392.1|1297258_1298650_-|VWA-domain-containing-protein	unknown	unknown	gnl|CDD|238119
NC_008312.1|WP_011610630.1|1305630_1306536_-|hypothetical-protein	unknown	unknown	unknown
NC_008312.1|WP_011610636.1|1318025_1318814_-|hypothetical-protein	unknown	unknown	unknown
NC_008312.1|WP_011610640.1|1326044_1326278_+|hypothetical-protein	unknown	unknown	unknown
NC_008312.1|WP_155994292.1|1307574_1307730_-|hypothetical-protein	unknown	unknown	unknown
NC_008312.1|WP_011610629.1|1303102_1305283_-|hypothetical-protein	unknown	unknown	unknown
NC_008312.1|WP_011610641.1|1327222_1330339_+|phosphoenolpyruvate-carboxylase	unknown	unknown	gnl|CDD|366019
NC_008312.1|WP_011610638.1|1320188_1322276_-|DNA-polymerase-III-subunit-gamma/tau	unknown	unknown	gnl|CDD|237862
NC_008312.1|WP_011610624.1|1296179_1296470_+|hypothetical-protein	unknown	unknown	unknown
NC_008312.1|WP_011610631.1|1306594_1307410_-|hypothetical-protein	unknown	unknown	gnl|CDD|214940
NC_008312.1|WP_011610633.1|1312664_1313972_-|methylglyoxal-synthase	unknown	unknown	gnl|CDD|234850
NC_008312.1|WP_155994294.1|1314880_1316677_+|ATP-binding-cassette-domain-containing-protein	unknown	unknown	gnl|CDD|224055
NC_008312.1|WP_011610622.1|1291959_1294113_+|hypothetical-protein	unknown	unknown	gnl|CDD|132835
NC_008312.1|WP_011610639.1|1322984_1323788_+|hypothetical-protein	unknown	unknown	unknown
NC_008312.1|WP_044137170.1|1330520_1331708_-|hypothetical-protein	unknown	unknown	unknown

HMMScan for Signature genes

Protein	Cas_name	Cas_description	E-value	Identity	Coverage
NC_008312.1|WP_011610626.1|1299129_1299747_-|hypothetical-protein	PD-DExK	mkCas0061_PD-DExK_CAS-I:CAS-III	1.5e-31	104.2	0.0

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_008312.1|WP_011610623.1|1294563_1295925_+|membrane-attack-complex-component/perforin/complement-C9	gnl|CDD|366826	pfam01823, MACPF, MAC/Perforin domain. The membrane-attack complex (MAC) of the complement system forms transmembrane channels. These channels disrupt the phospholipid bilayer of target cells, leading to cell lysis and death. A number of proteins participate in the assembly of the MAC. Freshly activated C5b binds to C6 to form a C5b-6 complex, then to C7 forming the C5b-7 complex. The C5b-7 complex binds to C8, which is composed of three chains (alpha, beta, and gamma), thus forming the C5b-8 complex. C5b-8 subsequently binds to C9 and acts as a catalyst in the polymerization of C9. Active MAC has a subunit composition of C5b-C6-C7-C8-C9{n}. Perforin is a protein found in cytolytic T-cell and killer cells. In the presence of calcium, perforin polymerizes into transmembrane tubules and is capable of lysing, non-specifically, a variety of target cells. There are a number of regions of similarity in the sequences of complement components C6, C7, C8-alpha, C8-beta, C9 and perforin. The X-ray crystal structure of a MACPF domain reveals that it shares a common fold with bacterial cholesterol dependent cytolysins (pfam01289) such as perfringolysin O. Three key pieces of evidence suggests that MACPF domains and CDCs are homologous: Functional similarity (pore formation), conservation of three glycine residues at a hinge in both families and conservation of a complex core fold.	2.47685e-31
NC_008312.1|WP_011610641.1|1327222_1330339_+|phosphoenolpyruvate-carboxylase	gnl|CDD|366019	pfam00311, PEPcase, Phosphoenolpyruvate carboxylase.	0
NC_008312.1|WP_011610637.1|1318856_1319852_-|multicopper-oxidase-domain-containing-protein	gnl|CDD|259910	cd11024, CuRO_1_2DMCO_NIR_like, The cupredoxin domain 1 of a two-domain laccase related to nitrite reductase. The two-domain laccase (small laccase) in this family differs significantly from all laccases. It resembles the two domain nitrite reductase in both sequence and structure. It consists of two cupredoxin domains and forms trimers and hence resembles the quaternary structure of nitrite reductases more than that of large laccases. There are three trinuclear copper clusters in the enzyme localized between domains 1 and 2 of each pair of neighbor chains. Three copper ions of type 1 lie close to one another near the surface of the central part of the trimer, and, effectively, a trimeric substrate binding site is formed in their vicinity. Laccase is a blue multi-copper enzyme that catalyzes the oxidation of a variety of organic substrates coupled to the reduction of molecular oxygen to water. It displays broad substrate specificity, catalyzing the oxidation of a wide variety of aromatic, notably phenolic, and inorganic substances. Laccase has been implicated in a wide spectrum of biological activities.	4.37073e-52
NC_008312.1|WP_081432392.1|1297258_1298650_-|VWA-domain-containing-protein	gnl|CDD|238119	cd00198, vWFA, Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b para-rossmann type of fold. The vWA domain, since its discovery, has drawn great interest because of its widespread occurrence and its involvement in a wide variety of important cellular functions. These include basal membrane formation, cell migration, cell differentiation, adhesion, haemostasis, signaling, chromosomal stability, malignant transformation and in immune defenses In integrins these domains form heterodimers while in vWF it forms multimers. There are different interaction surfaces of this domain as seen by the various molecules it complexes with. Ligand binding in most cases is mediated by the presence of a metal ion dependent adhesion site termed as the MIDAS motif that is a characteristic feature of most, if not all A domains.	3.96682e-14
NC_008312.1|WP_011610631.1|1306594_1307410_-|hypothetical-protein	gnl|CDD|214940	smart00962, SRP54, SRP54-type protein, GTPase domain. This entry represents the GTPase domain of the 54 kDa SRP54 component, a GTP-binding protein that interacts with the signal sequence when it emerges from the ribosome. SRP54 of the signal recognition particle has a three-domain structure: an N-terminal helical bundle domain, a GTPase domain, and the M-domain that binds the 7s RNA and also binds the signal sequence. The extreme C-terminal region is glycine-rich and lower in complexity and poorly conserved between species. The GTPase domain is evolutionary related to P-loop NTPase domains found in a variety of other proteins.	0.00383923
NC_008312.1|WP_011610622.1|1291959_1294113_+|hypothetical-protein	gnl|CDD|132835	cd00147, cPLA2_like, Cytosolic phospholipase A2, catalytic domain; hydrolyses arachidonyl phospholipids. Catalytic domain of cytosolic phospholipase A2 (PLA2; EC 3.1.1.4) hydrolyzes the sn-2-acyl ester bond of phospholipids to release arachidonic acid. At the active site, cPLA2 contains a serine nucleophile through which the catalytic mechanism is initiated. The active site is partially covered by a solvent-accessible flexible lid. cPLA2 displays interfacial activation as it exists in both "closed lid" and "open lid" forms. Movement of the cPLA2 lid possibly exposes a greater hydrophobic surface and the active site. cPLA2 belongs to the alpha-beta hydrolase family which is identified by a characteristic nucleophile elbow with a consensus sequence of Sm-X-Nu-Sm (Sm = small residue, X = any residue and Nu = nucleophile). Calcium is required for cPLA2 to bind with membranes or phospholipids. Group IV cPLA2 includes six intercellular enzymes: cPLA2alpha, cPLA2beta, cPLA2gamma, cPLA2delta, cPLA2epsilon, and cPLA2zeta.	0.00973278
NC_008312.1|WP_155994294.1|1314880_1316677_+|ATP-binding-cassette-domain-containing-protein	gnl|CDD|224055	COG1132, MdlB, ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms].	2.57536e-172
NC_008312.1|WP_011610633.1|1312664_1313972_-|methylglyoxal-synthase	gnl|CDD|234850	PRK00861, PRK00861, putative lipid kinase; Reviewed.	5.73922e-148
NC_008312.1|WP_011610638.1|1320188_1322276_-|DNA-polymerase-III-subunit-gamma/tau	gnl|CDD|237862	PRK14948, PRK14948, DNA polymerase III subunit gamma/tau.	0

Protein sequences

>NC_008312.1|WP_155994292.1|1307574_1307730_-|hypothetical-protein
MGEVYRSDRSLRKTHLALELSSPQRNHIPGSLVNQNYQNLEANYNRGNYYR
>NC_008312.1|WP_011610631.1|1306594_1307410_-|hypothetical-protein
MGNICIIGPTGAGKTTYLAGLAYWPEKTNPNFQITAITNDAKNLATKAENIILNGASLEPTIIDGIKIQSFYDLPLYSFHIEIKHWWQRKPEEINLVVRDYPGEIFNELQSGMSNTLHQEFFDECMIKDNLGCLILLHKWEPGNDIFYSNVIEKFINLIDEKDRTQDLRLAIAMSKCERGEIWPGRLDPELDIFKVHLPRTTNILKKRIPQQNLQFYAISTFGVLHRNDPRPNRTDELGSSHSILREPLKWKPYGIIPPLYWLSKGQYMKS
>NC_008312.1|WP_011610630.1|1305630_1306536_-|hypothetical-protein
MFKSIFKPRNNQELKVENHSGVLRVIGDRAAGKTTYMAALARWPNADISSPVELVTPANKDGESLIRQAQDLIEKGLQIEPTRLASDVLEIKDYSLRIVLKKTDNSKFSNTVLNLDISCKDYSGEFFSDVLQETNSQLLRDYLNDCFPATGIMLMIDGTTHRKDLEYARGVDQLLVALAGGNIFSQKRRIALVLTKCELADLWGNRHKPKFLLKARFPTIFKRLESWQDLGMGNVEYFTTSAFGATRNQNKYFQPNSEEIYRDRSGVASVLGDSKKWRPFGLVSPIYWICTGKRNLHLEQD
>NC_008312.1|WP_011610629.1|1303102_1305283_-|hypothetical-protein
MKNIEIHEFSTGIIPEILPNGQWISRGFKVGEYMNLTLPKIPYSLARAIANKGFEVGKDRHSQEPTFVGRVVLSMNDKEPDYSVVAVVTSGQDEYSRSTSFYRYFLCTGKDNIWQILDWINIQQQQGINPIFNPSETKQIGKPNKHQVTKKPEINLPKNWQNWLNTTTFPVIISTKLSDLQILNKMAELKANDLPISWIYNLEAVERPEQFIIIHPANAEVAANLTKIQTKMIKNSSSNTSRYIDEAAIETAIKGLISGSKIKQEWIENLVLKLQNGQITSEYLNNLFDNLGATNGIKQGNANAQMIRLLTLRAIFIPESLPEYLNWLNISRHRKKENEKQKISRQLQLQLRNYKKLLEPLIILGANHVLSQILGKKISVTDYCCLLKNQDSLWSAHSSIIKQQVRQDLKSLENSLLHKNPGQQKDELVYGNATWKKLIDFLKNRWDKTSSSYQKTSQKTSNYYQPFADLFYQLSDYELAAYFHQISNGKVPKEIFTAAFPKLKYFYQTIIFGLTVERELDFSDHITILIRKYRRSVAATFLIMFSHGLFFILGYQVGKLNSGNIVERKTQEYPLSSEEILTDVEKNTVSELSTEKMEKALEKFSTTRREIQKIVRELEVELLNQNSTLLTTEDARLEIIKAIHEILENDVKIQYIAGYKDDVIGEEDKYLVVKKQWIGAIYSYQKKFFSDGFGYIEPNKKTADKLKCDLADLLEINLQTRPQRCG
>NC_008312.1|WP_011610627.1|1299864_1300983_-|hypothetical-protein
MRIYLYILSGITSALIGWSIGQFILSDLGWFKKIPELALFPCIAISLAVGIVATDIFLSNPTRFKRNFSRGIIPLSIAGGLGFLIGITSGALVQILLNPQLRDKVITIPDEFVRIVGWILIGGAVGLAEGLTWRWRSIEAGDKRRFWQRLTISLGTSILTALLAAIIFEWIRHKMGGMPIALKAWEDTIGFSLLGGLLGLVLSFSTSPSHLVALRAGAGFEYIENLDISQYQTPNNYPHIQKELLPRLKFVSNDLTDKIEEGLSIQLPPRGKVKIGSAQLKIFGNQQFGVNICIPGLPLHIADLDLEPSQTILVPNLKFFNRIEYQGDRLTESTPIKLKHNDLITFHAENGIYNNQKLFRFVYYNRFLDPQG
>NC_008312.1|WP_011610626.1|1299129_1299747_-|hypothetical-protein
MINIRIELPDSCNFSDYFKFNYYPEDILNYFGYQLIKEELVLPKSQRQINGLENLKQRFRKSLPYITLDSEIAKREFLIAPVLIELVDYCQAQLKVSYPLEVEPQLRGSLDYFLQAGNNLLVIEAKDENLERGFKQLAVELIALDKRTEPAQNLLYGAVSIGKIWQFALLKRLDKEVKQDLNLYRVPNDLEDLMKILVAILTGVK
>NC_008312.1|WP_081432392.1|1297258_1298650_-|VWA-domain-containing-protein
MLKMLILKNYSYLSTKIYFFARDLSLSLLIVICYINPVFAKVKNLEIIEAIPDRNEGKVTLRVKVYDQKNKPIRGMQKNEFNLTVCPPKSDPKTGECQTLNQADINLKIPQPKELPPAWVIVLLDFSGSMKQLDSSGEKTKLEGAIAAIRKFNQDLAKKGENTRISIVPFGKGGKNCPGNQVRKKQLDNFVLAGKKKVEQTLNKLESKLDNLCAATDIYEPLRQAVQFFGNPEDTRFNLPINSNLPQPRRSIILLSDGYHSIYGNRENEPELEAQDFEKMMFMLKSYPNITVHTLGYGLTPQQLQQKYDLKQSPTIRDISKRGRKKSNGSEKLREVAAEEFVDQRRLQQIAGVTNGIAEFSGNAENISTSLTEFLEALFDEYQINYIQPINADRGSLHNVQVSFKLPNNLVDSELEPYVFPWVSRSLPPLTRIIIFLFTLAALLGGGVIPFLLWAKSIKREFQ
>NC_008312.1|WP_011610624.1|1296179_1296470_+|hypothetical-protein
MDKLYKFGKVWAQTEITVRLAIAYFNWILVHRRKENTAAQRAEERDRSLELERPLYFSHTLRSALPASFSYISVYNCADYSKSLSSNSDCNFSKQT
>NC_008312.1|WP_011610623.1|1294563_1295925_+|membrane-attack-complex-component/perforin/complement-C9
MTQFTEKEIEVIHNYLGRGYRGYENYATANSMTYPLFDLKSCRVDDYVDLLRATTYESEVIIGKSMQEYIKKLSINAGISVGYAFLGEIENRFDMSDDKSSKRTNEYISYDINNTLYRITLKGNVPLSEQFQEDLNSLDATTLFEKYGTHYLKSTWIGGRISFSTTIDTYGMTDDMRKKFAFVTKRKVGNWTGTSDVELTREEKDISEKMKSNSIVRVWGGDPKLGRDIERAIQGHTVSDIYQQWGQTVEERPYISDFDHGQGLVPIYELATGTRKEQLKEQWEAYWQDKSDKEEGLIGPDLVKKDHTIVLSSRDGRYLSFSYSGNQYYYAKLGNNPLSHQLDTNNEDLCHGNIVHLKTTEQFNGKWNQRKLLGAFADSYELYYWSDDGDKTKWIIEKAAGTAQEKEIAYGDKVYIKNKSYNQYLVPAKNGYLTTKKIQNPTDEHTWVIHRPE
>NC_008312.1|WP_011610622.1|1291959_1294113_+|hypothetical-protein
MDKNTPIYIAISGGGFHSHTAMSAWISGILHHSELESLEQIFENVRGISANSGGSWFMSHLGYSNAFVKSLLEDSQSEKSTWSSSGYLGKMGESFFSKDDEKASDMSIFSPVKIETFLAKYIDLFNVYAEIFPNGNRRWHQFVTTKVYEPLEKLGNAENGFETMKGKKLSETNDRLPWFREKDFVIAAGLLNSKVVLHATGGLGSTNQVYSVNSADGSKLRNFVPMCLSGVANGRKAAPVFVSGPQEVIYSEESKWRIPLTANHPQNLNLLDATIASSSAIAFLASESSIGEMIPSLNEGLTFEWISYQEADFAPPIRFGNDRIEILKTLERASYDEFANQKMARVADGGYLDNTSVVFQLRHMKENGDLKDGFHLVLFVNGSDEGVKYHGYEMNVGIATLFGHDGLSEAHRAERVKKGEKIQPEEGSIWNSPFSDLCMEIPSPHVFETEPLENNTAISMWNWKSKDEKISLQARKIPVTTVENKTYGISAGVMGTIYIFEVTQPESFPMPTHRDILETYEYLFETIRNEACAKNQALSHLKEALALKINIPTDPHPIPEIVKKNDNIVLQWNSDGSYLSSSDSGFRYYLATLNRLKSYAKIHKFDNMYSDNLHHGDLVRIKTTEQFKGIWNQRKLLGAFANSYELYYWSDSGDKTNWIIEKAAGTAQETEIAYGEKVYIKNKSYNQYLVFAKDGYLTTKKIQNPGDEHTWVIHRPE
>NC_008312.1|WP_011610633.1|1312664_1313972_-|methylglyoxal-synthase
MGNTIALLAYDSKKDNLVEFVKKHKIVLSRYQLVATESTAQYILQEVDIEINSVLAGPLGGDAQLAVEVTTGNVVAVICLVDYLFSQSYEPDIKLLLRLCQVHNVPIAINIATAEIIIKGFIQTTVAHLIFNPISGKGNAQQDLLLIKSLLEPHLHLDIHQTTPEKTAEELTELAIAKQADIIIACGGDGTVSAVAGALVNTNIPLGIIPRGTANAFCMALGIPSIAPIRGACDLILAGKTRVIDVGRCNERTMILLAGVGYEAETIERADREAKNRWGVLAYMMAGWRQLTEQQLFDIEIEIDGVAKTFQAGAITIANAAPPTSFLAQGLGKVIMNDGLLEVMIITSKNTLQAVNAGVRMFGSAIFQTPTQHEDTIALRTKRVKVSADPPQKVVLDGEIIGTTPIEVECIPNGLTVLAPPTNEAEEKPAWGFFS
>NC_008312.1|WP_155994294.1|1314880_1316677_+|ATP-binding-cassette-domain-containing-protein
MKLPKKTLKPKHPFLRLLNYGNAYKAQTWQGVIYSILNKIFDLAPPVLIGAAVDVVVKKEDSLIAKFGIQDTFSQLLALAFLSLIVWGLESIFQYAYQRLWRNLAQNIQHNLRIEAYSHLQDLELAYFEERSTGNLMTILNDDINQLERFLDVGANKIIQVTVTVIIIGSAFFVLVPSFALWAVLPMPFIIWASTWFKNFLAPRYAEVREKVSLLNSQLSNNLSGITTIKSFTAETYEVGRITRNSNAYKSKNTKAIAFSAAFVPLIRIIIFIAFVATLLLGGLEAVDGRLAVGTYSIMVFLTQRLLWPLTSLGETLDLYQRSMASINRVMNLLDTPITIHPGDKPLSVEFIKGELELENVTFSYQKNFPTIQNISMKIPAGKTIGIVGSTGSGKSTIVKLLLRFYEIQSGKITLDGIEINQINLQDLRRAIGLVSQDIFLFHGTVIENISYGSFDATLSEIIAAAKIAEADNFINKLPQGYDTIIGERGQKLSGGQRQRIALARAVLKNPPILILDEATSAVDNETEAAIQKSLEKITQNRTTIAIAHRLSTIRNADCIYVMEHGQIVEVGRHEELLKKSGTYSTLWRVQSGLKLVS
>NC_008312.1|WP_044137169.1|1317055_1317484_+|hypothetical-protein
MTFNNNLPQKNQNNWQHQLDKFVKANQKELAALAWGLKLENGETDETIGIDLKETPKFVYCSKAAIETLNRNVDGKIQEILGLIDGYKPEIEVLMIAIGDSQIKLVYFQPEISPPNCFEQLGHNLDALLEILETGMSQFINL
>NC_008312.1|WP_011610636.1|1318025_1318814_-|hypothetical-protein
MMNINTILRYFLVGFLATLLAIVFHPNIQETVSNNSMFLGTPSIAVSPESKDIDYMSNLGLMKGHLLVGKELIVAQEEKEAEPHFAHPIEELYIDIENELNDRGIKQFKNSLNNLHDLVIAGAKDTNKFNSMYQQTMEEIDGAISNLPSKKRQNPKFVLQVINELLDTAGAEYEAAILDGKIVEVIEYQDSRGFVDYAEILYKNIADTMGSKYSDIDGKIQADMAKLKKAWPSVLAPEIVAMEPAKVSKLIQEIKQNSEKIG
>NC_008312.1|WP_011610637.1|1318856_1319852_-|multicopper-oxidase-domain-containing-protein
MANLPLPKPEKSEFWNRRQFLKLGIVGTGVTLAGISTQHILPLLSSSLKAQAAINAIELDPMNTLRDFDYGMLKEENGRKIREFQIKAINSKLQLNQAVSLISWNYNGRVPGPTLRATAGERVRIIFENEGGHAHTMHFHGIHPAEADGVRPVRHGKTTVYEFDARPFGVHLYHCHITPVTRHISKGLYGMFIIDPPEGRPPADEIVLVMGGYDTNNDGKNELYAFNGLPNYYKTHPILIQQNKLVRLYILNMIEFDSAATFHIHGNFFQVYPTGMTVKPWQKTDVVTMGTSERHILEFYYSFPGKYMFHPHQDAIAESGCIGLFEVLPQA
>NC_008312.1|WP_011610638.1|1320188_1322276_-|DNA-polymerase-III-subunit-gamma/tau
MAYEPLHHKYRPQTFADLVGQDVIAQTLTNAIHTKRIAPAYLFTGPRGTGKTSSARVLAKSLNCLSYDHPTPSPCGTCNVCVGITKGSTLDVIEIDAASNTGVDNIRELIERSQFAPVQCRYKVYVIDEVHMLSVSAFNALLKTLEEPPKGVVFILATTDPQRVLATIISRCQRFDFRRIPLEAMVKHLHHIAIEEKIDITTEAIQMIAQIAQGGLRDAESLLDQLSLLAGEITVERVWDLVGAVPERDLMVLVEAIAADNSIKVLKCTRQIMDRGKEPIIVLQNLAGFYRDLLIAKTAPTSKNLVALTKPTWEKLCQFSQDWDIGTILAGQKHLQTSEVQIKNTTQPRLWLEVTLLGLLPSALPKFNQLEKQETRDISQNVSVKNTSKNLSQPLTKKPISEKPKQQISEPKEVSKEVPIAPKSEDFFTSSTNDTAKKSSSDSLETDKIKNESELQNIWEKVLAEVKPHSTQALLSQQVILLGYNNELARIGISSKNLEKMVIHKIPNIEAAFEKIFQTSVKVKVEVKNSQQKQHSFRENIYPNHSPRERLNSNNKLRQENSNYDDKIAEDEPENFPVSYPSNSQKEKKTTPNFSLPNSPLNDLVEKEKYPEGKRDSVAIATRRIVNFFKGEIVDIKSIKLPDKIDQADKTDLPATSESSDLSIDVQSQKSKNSHVGIDEPEENEGDNFNDDIIF
>NC_008312.1|WP_011610639.1|1322984_1323788_+|hypothetical-protein
MLTPIIVVESRLAQVSPPPEPNLLKIEYVWMGVSGLLLILLIILGIFHKAKIKGFNKKLSLEVFRNKNLQQKYKLALATIAKMEKNPDLIHSREFNLDCLRMRMEEEAFNFGIVNQIKEKVKQHINIALQPNSSITGEKRNPNDQKINSIFEVEYKTGETGKNQIKRVLFRVSIKLKKLSNQVSYQTINQIIDCLETYLSPNNDHDNWTPTIQGQIVHIDWDKKAKPVPMLVVEQFNDEVILRTNKSILKSPTALQPELPADSKKYH
>NC_008312.1|WP_011610640.1|1326044_1326278_+|hypothetical-protein
MPSFRENSSENPTITTPSWKISSELVLSLATGPVLLGLLSNKAINELLLEIGLYSEEIFRGDRLPILKFPQKNPLDL
>NC_008312.1|WP_011610641.1|1327222_1330339_+|phosphoenolpyruvate-carboxylase
MSSLLHSKEITLEPGFKNPKMTASDLFLHNRIKIVENLWESVLRQECGQELVDILQKMRSGHSPEGQASDFLGSEIEQLIEKLELKDAIRAARAFALYFQLINIVEQHYEQKIQQLAYSHNNSLEKLISKDDIAKDHDTRSLRVESIPVWNDNRIKHEGEGTFHYLFPLLQTLNVPSQLIQRLINNLDIRLVFTAHPTEIVRRTIRTKQRRIAKILQQLDQVNESLSESHVDEEQVNSLVSSWKIESLKEQLTEEILLWWRTDELHQFKPSVLDEVETTLHYFNEVLFDATPELHRRFKQALHSSFPYLKPPSYNFCKFGSWVGSDRDGNPFCTPAVTWQTACYQRQIVLEKYLNAIDRLKELLSLSLHWSDVLPELLDSLDRDHIQMSEVYDQWAIRYRQEPYRLKLSYIKKRLENTRDRNARLYNGDEVQRQKKEVLSQRQKQVLSQYQETKSIYHSSADFLAELQLIQRNLKETGLSCSDLENLISQVEIFGFNLARLDIRQESSVHEAAIQEITEYLQILPKSYIEMSEAERTEWLSTELPTRRPLIPTELPFSEKTCEIINTFRMLRELQLEFGEEICQTYIISMSRDVSDLLEVLLLAQEAGLYDPATGASSIHVVPLFETVEDLRSAPRVMHDLFKLSLYRAGLAGGYDKLSKEPINELVNEAPYLQEVMLGYSDSNKDSGFLSSNWEIHKAQKALYKVGEEHGIALRIFHGRGGSVGRGGGPAYKAILAQPGKSISGRIKITEQGEVLASKYSLPHLAMFNLENVTTAVIQASLLHTGFDEIETWNQIMEELAVRSRSHYRNLIYEQEDLVEFFYQVTPMPEISQLQISSRPARRKNDKKKTISGLRAIPWVFSWTQSRFLLPAWYGVGTALQEFVEKEPEEHLKLLQYFYVKWPFFTTAISKVEMTLAKVDLQIAHYYVRELSKPEDRERFETLFEEITIEYHLTRNLVLQISGHQRPLDGDPDLQRSVQLRNATIIPLGMLQVALLKRLRQHDTGTPGVINSRYSKSELLRGALLTLNGIAAGMRNTG
>NC_008312.1|WP_044137170.1|1330520_1331708_-|hypothetical-protein
MADFFGIFGQKEAFTLLIAIDRETNYNDFLKAEAGFNSYKLAILDKGIQNSPYQNQVENYPEHLKMLSSLATPRAKAFPHVGELPEIDEQALSFIHPDIKEACICLGGNAGGLFKSRWLGRNSLDKCQYWSSTKVIAILNIICSLSSLNNDINTCQIRGDGKNIDFNEAVEDVITYAEKVGSSNALSAMFKCFQTYVGLESWLKEITGNNHTEFQGLYGEEPFIISPEIVQDNQVLLSAVSEIKKPEDQTGENVVTAYDLTRIMSMVGWYYHLPEPAKLPGMSWKNLQPLIRNTGKDSARYVDVALEKLGIQNSIKYPVILSKLGFGYTKSRKRTELTYTCFTQFEYQEKVKSIAMTLRGAKALGDCDREAVEIDARMAAEVTEIIRLLVTDELV

Crispr_ID: NC_008312_10

• CRISPR_ID: NC_008312_10
• CRISPR_location: 1399189-1399253
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NC_008312_10

Consensus_repeat	Method
TTCAAAGTTAGAGTTTAGAAGTT	CRISPRCasFinder

spacers of NC_008312_10

>10.1|1399212|19|NC_008312|CRISPRCasFinder
AGAAGTTAAAAGTCAAAAG

CRISPR arrays and Neighbor proteins around NC_008312_10

CRISPR arrays

The CRISPR arrays of NC_008312_10

>merge|NC_008312|10|1399189-1399253|CRISPRCasFinder
TTCAAAGTTCAAAGTTAGAGTTTAGAAGTTAAAAGTCAAAAGCTCAAAGTCAAAATTTCAAAGTT

>NC_008312|10|8|1399189-1399253|CRISPRCasFinder
TTCAAAGTTCAAAGTTAGAGTTT	AGAAGTTAAAAGTCAAAAG
CTCAAAGTCAAAATTTCAAAGTT

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_008312.1|WP_155994298.1|1387058_1387208_-|hypothetical-protein	unknown	unknown	unknown
NC_008312.1|WP_011610682.1|1410905_1411763_+|hypothetical-protein	unknown	unknown	gnl|CDD|225528
NC_008312.1|WP_155994296.1|1386864_1387017_-|hypothetical-protein	unknown	unknown	unknown
NC_008312.1|WP_011610680.1|1408254_1408719_+|TM2-domain-containing-protein	unknown	unknown	gnl|CDD|377473
NC_008312.1|WP_011610675.1|1401368_1402571_-|argininosuccinate-synthase	unknown	unknown	gnl|CDD|234785
NC_008312.1|WP_011610674.1|1399968_1400772_+|thermonuclease-family-protein	unknown	unknown	gnl|CDD|224442
NC_008312.1|WP_011610677.1|1404360_1404582_+|hypothetical-protein	unknown	unknown	unknown
NC_008312.1|WP_081432523.1|1391234_1393301_+|PBP1A-family-penicillin-binding-protein	unknown	unknown	gnl|CDD|273955
NC_008312.1|WP_011610667.1|1384182_1384845_-|tRNA-(guanosine(46)-N7)-methyltransferase-TrmB	unknown	unknown	gnl|CDD|234649
NC_008312.1|WP_011610678.1|1406489_1407422_+|methyltransferase-domain-containing-protein	unknown	unknown	gnl|CDD|178418
NC_008312.1|WP_011610670.1|1388872_1389853_+|chlorophyll-synthase-ChlG	unknown	unknown	gnl|CDD|131111
NC_008312.1|WP_155994641.1|1385318_1385525_-|transposase	unknown	unknown	gnl|CDD|366606
NC_008312.1|WP_011610669.1|1387488_1388583_+|ArsA-family-ATPase	unknown	unknown	gnl|CDD|349755
NC_008312.1|WP_044137173.1|1412247_1412706_+|superoxide-dismutase,-Ni	unknown	unknown	gnl|CDD|378114
NC_008312.1|WP_011610673.1|1395949_1399156_-|efflux-RND-transporter-permease-subunit	unknown	unknown	gnl|CDD|223911
NC_008312.1|WP_011610679.1|1407783_1407951_+|YqaE/Pmp3-family-membrane-protein	unknown	unknown	gnl|CDD|376592
NC_008312.1|WP_011610676.1|1403155_1404088_+|glycosyltransferase	unknown	unknown	gnl|CDD|133042
NC_008312.1|WP_011610672.1|1394262_1395375_+|geranylgeranyl-reductase-family-protein	unknown	unknown	gnl|CDD|273936
NC_008312.1|WP_011610681.1|1409260_1410328_+|branched-chain-amino-acid-aminotransferase	unknown	unknown	gnl|CDD|237363
NC_008312.1|WP_011610666.1|1381499_1382981_+|phospholipid-carrier-dependent-glycosyltransferase	unknown	unknown	gnl|CDD|224839

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_008312.1|WP_011610682.1|1410905_1411763_+|hypothetical-protein	gnl|CDD|225528	COG2981, CysZ, Uncharacterized protein involved in cysteine biosynthesis [Amino acid transport and metabolism].	1.63049e-32
NC_008312.1|WP_011610670.1|1388872_1389853_+|chlorophyll-synthase-ChlG	gnl|CDD|131111	TIGR02056, chlorophyll_synthase_33_kD_subunit, chlorophyll synthase, ChlG. This model represents the strictly cyanobacterial and plant-specific chlorophyll synthase ChlG. ChlG is the enzyme (esterase) which attaches the side chain moiety onto chlorophyllide a. Both geranylgeranyl and phytyl pyrophosphates are substrates to varying degrees in enzymes from different sources. Thus, ChlG may act as the final or penultimate step in chlorophyll biosynthesis (along with the geranylgeranyl reductase, ChlP). [Biosynthesis of cofactors, prosthetic groups, and carriers, Chlorophyll and bacteriochlorphyll].	5.26851e-180
NC_008312.1|WP_011610680.1|1408254_1408719_+|TM2-domain-containing-protein	gnl|CDD|377473	pfam05154, TM2, TM2 domain. This family is composed of a pair of transmembrane alpha helices connected by a short linker. The function of this domain is unknown, however it occurs in a wide range or protein contexts.	1.46076e-10
NC_008312.1|WP_011610675.1|1401368_1402571_-|argininosuccinate-synthase	gnl|CDD|234785	PRK00509, PRK00509, argininosuccinate synthase; Provisional.	0
NC_008312.1|WP_011610674.1|1399968_1400772_+|thermonuclease-family-protein	gnl|CDD|224442	COG1525, COG1525, Micrococcal nuclease (thermonuclease) homologs [DNA replication, recombination, and repair].	4.45462e-19
NC_008312.1|WP_081432523.1|1391234_1393301_+|PBP1A-family-penicillin-binding-protein	gnl|CDD|273955	TIGR02074, Includes:_Penicillin-insensitive_transglycosylase, penicillin-binding protein, 1A family. Bacterial that synthesize a cell wall of peptidoglycan (murein) generally have several transglycosylases and transpeptidases for the task. This family consists of bifunctional transglycosylase/transpeptidase penicillin-binding proteins (PBP). In the Proteobacteria, this family includes PBP 1A but not the paralogous PBP 1B (TIGR02071). This family also includes related proteins, often designated PBP 1A, from other bacterial lineages. [Cell envelope, Biosynthesis and degradation of murein sacculus and peptidoglycan].	0
NC_008312.1|WP_011610667.1|1384182_1384845_-|tRNA-(guanosine(46)-N7)-methyltransferase-TrmB	gnl|CDD|234649	PRK00121, trmB, tRNA (guanine-N(7)-)-methyltransferase; Reviewed.	1.21771e-62
NC_008312.1|WP_011610678.1|1406489_1407422_+|methyltransferase-domain-containing-protein	gnl|CDD|178418	PLN02823, PLN02823, spermine synthase.	8.23892e-100
NC_008312.1|WP_155994641.1|1385318_1385525_-|transposase	gnl|CDD|366606	pfam01385, OrfB_IS605, Probable transposase. This family includes IS891, IS1136 and IS1341. DUF1225, pfam06774, has now been merged into this family.	4.98116e-06
NC_008312.1|WP_011610669.1|1387488_1388583_+|ArsA-family-ATPase	gnl|CDD|349755	cd02035, ArsA, Arsenical pump-driving ATPase ArsA. ArsA ATPase functions as an efflux pump located on the inner membrane of the cell. This ATP-driven oxyanion pump catalyzes the extrusion of arsenite, antimonite and arsenate. Maintenance of a low intracellular concentration of oxyanion produces resistance to the toxic agents. The pump is composed of two subunits, the catalytic ArsA subunit and the membrane subunit ArsB, which are encoded by arsA and arsB genes, respectively. Arsenic efflux in bacteria is catalyzed by either ArsB alone or by ArsAB complex. The ATP-coupled pump, however, is more efficient. ArsA is composed of two homologous halves, A1 and A2, connected by a short linker sequence.	3.03155e-64
NC_008312.1|WP_044137173.1|1412247_1412706_+|superoxide-dismutase,-Ni	gnl|CDD|378114	pfam09055, Sod_Ni, Nickel-containing superoxide dismutase. Nickel containing superoxide dismutase (NiSOD) is a metalloenzyme containing a hexameric assembly of right-handed 4-helix bundles of up-down-up-down topology with an N-terminal His-Cys-X-X-Pro-Cys-Gly-X-Tyr motif that chelates the active site Ni ions. NiSOD catalyzes the disproportionation of superoxide to peroxide and molecular oxygen through alternate oxidation and reduction of Ni, protecting cells from the toxic products of aerobic metabolism.	1.98852e-68
NC_008312.1|WP_011610673.1|1395949_1399156_-|efflux-RND-transporter-permease-subunit	gnl|CDD|223911	COG0841, AcrB, Cation/multidrug efflux pump [Defense mechanisms].	0
NC_008312.1|WP_011610679.1|1407783_1407951_+|YqaE/Pmp3-family-membrane-protein	gnl|CDD|376592	pfam01679, Pmp3, Proteolipid membrane potential modulator. Pmp3 is an evolutionarily conserved proteolipid in the plasma membrane which, in S. pombe, is transcriptionally regulated by the Spc1 stress MAPK (mitogen-activated protein kinases) pathway. It functions to modulate the membrane potential, particularly to resist high cellular cation concentration. In eukaryotic organisms, stress-activated mitogen-activated protein kinases play crucial roles in transmitting environmental signals that will regulate gene expression for allowing the cell to adapt to cellular stress. Pmp3-like proteins are highly conserved in bacteria, yeast, nematode and plants.	2.44148e-10
NC_008312.1|WP_011610676.1|1403155_1404088_+|glycosyltransferase	gnl|CDD|133042	cd06420, GT2_Chondriotin_Pol_N, N-terminal domain of Chondroitin polymerase functions as a GalNAc transferase. Chondroitin polymerase is a two domain, bi-functional protein. The N-terminal domain functions as a GalNAc transferase. The bacterial chondroitin polymerase catalyzes elongation of the chondroitin chain by alternatively transferring the GlcUA and GalNAc moiety from UDP-GlcUA and UDP-GalNAc to the non-reducing ends of the chondroitin chain. The enzyme consists of N-terminal and C-terminal domains in which the two active sites catalyze the addition of GalNAc and GlcUA, respectively. Chondroitin chains range from 40 to over 100 repeating units of the disaccharide. Sulfated chondroitins are involved in the regulation of various biological functions such as central nervous system development, wound repair, infection, growth factor signaling, and morphogenesis, in addition to its conventional structural roles. In Caenorhabditis elegans, chondroitin is an essential factor for the worm to undergo cytokinesis and cell division. Chondroitin is synthesized as proteoglycans, sulfated and secreted to the cell surface or extracellular matrix.	5.83214e-32
NC_008312.1|WP_011610672.1|1394262_1395375_+|geranylgeranyl-reductase-family-protein	gnl|CDD|273936	TIGR02032, Uncharacterized_protein_MJ1520, geranylgeranyl reductase family. This model represents a subfamily which includes geranylgeranyl reductases involved in chlorophyll and bacteriochlorophyll biosynthesis as well as other related enzymes which may also act on geranylgeranyl groups or related substrates. [Biosynthesis of cofactors, prosthetic groups, and carriers, Chlorophyll and bacteriochlorphyll].	5.53283e-85
NC_008312.1|WP_011610681.1|1409260_1410328_+|branched-chain-amino-acid-aminotransferase	gnl|CDD|237363	PRK13357, PRK13357, branched-chain amino acid aminotransferase; Provisional.	1.0469e-156
NC_008312.1|WP_011610666.1|1381499_1382981_+|phospholipid-carrier-dependent-glycosyltransferase	gnl|CDD|224839	COG1928, PMT1, Dolichyl-phosphate-mannose--protein O-mannosyl transferase [Posttranslational modification, protein turnover, chaperones].	6.77078e-42

Protein sequences

>NC_008312.1|WP_011610673.1|1395949_1399156_-|efflux-RND-transporter-permease-subunit
MFTNFFIKRPVFASVCSLLIILIGLVGYISLPVQEFPSIDTPVVSVRTNYPGASPEVVETEVTEILEAEINGVEGVKTLTSSTREGSSSINVEFQLSRNIEAAAQDVRSRVSRAMRRLPNEVDAPVVSKRSSDEERIIWLSLTGEKYSSLELSNYADKFIKNILETVNGVGSVFIGGERRYAMRLWLNPQKMAARNITALDVKQALRQQNVEIPSGRIEGKSTEYPIRTIGRLQTPEAYENLVIRRNDDTSLTRFKDIGRAEIGAESNRTIARYNGKPAIGIGISKLSGANIIEVATSVKTRMKELSKDFPDGMEYYVSVDYSTFVEVAIKEVWKSLLFAICLVVLVIYMFLQNWRATIIPTITIPISLIGAFGVMFFMGFSINTLTLFALTLSTGLVVDDAIVILENIVRYIQQKGKTPMEAAILGVGEVVFAVIATTIVLIAVFLPVGFSGGGAGRIFNEFALTIAVSVVFSTFVALTLAPSLSGRILKKQEPEEQKNFISRLFTIPLNLFDYALSRISVIYDRSLRLLMRIKPLVILGFILSFWIIVWLFQQLPQGFLPTEDRGRVFVSVTAPEGVSIEYTDNVMGQVENKLAQVPEMKGYFSITGFGRSAQANRAFAFTNLKPWSERTKPGQAQQEVVKKLFRAFAPITDARIFPINPGSLPGTGLSRSIQFVLQGNDFEELVRVSEEFNNEAQQLPQLKNVDTDLKINKPEIVVEINRYQAANLGISVENIAQTLQIMMGGEDITNFTQGNQRYDVIVRAEDEFRNNLQDIEDLYVRTEQGVMIPLSNVVTVKTSTTPPEINHFNRFRSATITGSPAPGVSLGEALQALYDLADRVLPADMRIDLKGESSQFRDAGQATTYIFGLALIFIFLTLAAQFESYIDPLVILLSVPLSLLGAFGALWLADLEVNVYSRIGLIMLIGLATKNSILIVEFANQLLAEGMSITKAAIEASRLRFRPILMTGFSTIFGVMPLAFASGPGAASRVSIGMSVMGGMLVSTVLTLYVVPVFYVVMGKSLQFGLFRKHAQYSADGDEISNGSVNGNSKTAPVNDKNQDSAEKLSR
>NC_008312.1|WP_011610672.1|1394262_1395375_+|geranylgeranyl-reductase-family-protein
MFDCIIVGSGPAGASAAYHLAKNGRSVLVLEKETLPRYKPCGGGVSPIVQEWFDFDFTPAISLKINSICYTWKKGDLVEVKLQNKQPIWMVRREIFDYFIIQKAQKQGAEIRDKTRVIGIEFKNNNWQVYTDNQSFTSPYLIAADGAKGSMAKWLGFKNRKRFAGGAMEIEIPVKNQKIDSAYFEFGMLNNGYVWNFPKADGYSIGVGTFWRKHGQNFTALLTEYTSMFEVNIQNVQKFGHPLCLWNGNQKLHTQNAVLAGEAACIVDPFTAEGIRPSIFTGVKAARAIHNSLNGDLFALEKYTQIINEEWGKDMVWAQRLAQGFSRFSHIGYQVGVKRPHATNIMTKIMSGELRYSDVVGSALRRLWQR
>NC_008312.1|WP_081432523.1|1391234_1393301_+|PBP1A-family-penicillin-binding-protein
MLSQKFQEPLQAPKFDGRKSQKKKVNPVEKKTGKKVIDVNIKGILLSWKLWLGLGLIGISSIMIYGGWMWRKLEQSLPEVADISSYRRDGTLTIKATDGKIIQQTGPATREKIKLQDIPTPLVQAFIAVEDRRFYEHRGVDYPGVIRAFILNIIARDIVQGGSTITQQLARMVFLDMEQSIWRKLREAMLAWKIENELSKEEILELYLNIVYLGSGTYGVADAAWVYFSQPVFGLTLAQMATLAGLPPAPSQYSPLVNEEAAKRRRNLVLKEMQAAGLISDERTKRAIAQPMKIKPSAPKRLIVEAPYFANYIQKELPKYVSSEVIMAGGLTVETTLDRRWQEIGEKVIQEAVDIDGYRQRFDQAALVAIDANTGEVKALVGGRDFAKSEFNRAIQAQRQPGSTFKSFVYAAAVAAGIPPTNGYRDLPFTVDGYKPKNYGKKYGGWRSMIDSLAYSVNVVAVQVLIDVGFEPVINLAKDMGIKSEVKATYSMALGSWEVNLLELTNAYATFAAQGKYIPAHGIKKVINQNGKVIYESNFKPKQVLDKDSAAIVTWMLENVVKYGSGANAYLSDRPVAGKTGTTEEARDLWFIGYIPQVATGIWFGNDDNKPTWGVSSTAAYNWQQFMRKVAKDIPVKNFPKKPSFYDRKPTIESKPVTPRWTRYGNVGPDGRELEKRNYYRDYYDGSY
>NC_008312.1|WP_011610670.1|1388872_1389853_+|chlorophyll-synthase-ChlG
MTNKEPEKLENSTAKTRQLLGMKGAASGETNIWKIRLQLMKPITWIPLIWGVVCGAASSGNYSWNLENVLMSAACMLLAGPLMAGYTQTLNDFYDREIDAINEPYRPIPSGAISISQVVTQIVFLLLAGVGLSYLLDLSAGHEFPILTMLCLLGAFLAYIYSAPPLKLKQNGWLGNYALGSSYIALPWWTGHALFGELNLTIVILTLFYSFAGLGIAVVNDFKSVEGDEKLGLKSLPVMFGIGTAAWICVLMIDIFQAGVAVYLISIKENLYAVILLLMVIPQITFQDMYFLRNPLENDVKYQASAQPFLVLGMLITGLALGHAGV
>NC_008312.1|WP_011610669.1|1387488_1388583_+|ArsA-family-ATPase
MTITYTFLGKGGTGKTTIAFATAKRYASQGKRVLFVGQEPASTLSLILGANIGPEPTEIDSNLKAVHIQAASLLESGWKELKKLEAEYIRTPFFKKVYGQELGVLPGVEGILTINAMQEYSASGKYDLIIYDGTGDKETLRLLGSAEIMSWYIRRFRQVILDSDLYKAISPFVQPVSNAILNVDWTGNNFSQPTEKINELLDNAKATIADPNRVAAYLVTTKDKAAIATARYLWGSAQQVNLTVGGVILNQADNVDNITAEFSPLSVTPVPHGSNENWQLLMDALPDFSQAVKAPKPIIIDIQKSQVSLFLPSFDKKQIGLIQDGPEVTIEAGDQRRNIFLPPPLSGRPVRGAKFKDDYLIISF
>NC_008312.1|WP_155994298.1|1387058_1387208_-|hypothetical-protein
MAITYQSNIQNMVDTWNMEVPTGLLGLGWNMSYEIIAIDNRNTGANYND
>NC_008312.1|WP_155994296.1|1386864_1387017_-|hypothetical-protein
MYQDSLTDDGARNFETEDYKPWGICYYSRDKKWVIIKENGVKQRKQRKER
>NC_008312.1|WP_155994641.1|1385318_1385525_-|transposase
MSNAIPKFSKEVGYANLKAAQLKIARLLRKVVSIRQNGLHKLRIYLTENHGKIVIENLNFRVMFPWVT
>NC_008312.1|WP_011610667.1|1384182_1384845_-|tRNA-(guanosine(46)-N7)-methyltransferase-TrmB
MVRVRIRQHVNPLASKYQQSVTIPNFSDIYADIKKPLYLDIGCARGRFLWQMAQVEPEWNFLGLEIREPLVIEANNWRDEKGLNNLHYLFCNANISLGKIFESFPKGILKKVSILFPDPWFKRRHQTRRVVQPKLVEDLANYLTVGGEVFLHSDIEKVAKEMCNRFSAHGSFYRSYNDWLKENILPVLSEREKVTLGKNQPVYRALFIKLEEPTPNIISP
>NC_008312.1|WP_011610666.1|1381499_1382981_+|phospholipid-carrier-dependent-glycosyltransferase
MQPISHQSNKWFVIGIASIFLFSAILRFWQLGRFNTLVFDEVYYAKFANNYLTQTEFFNAHPPLSQYIIAIGIWIGSHLPFGQEIVNNETGSTLAAWSYRWVNALTGSFIPLVVGAIAYKLTHRWSYSLIATLLMALDGLFLVESRYALNNIYLVIFGLLAHLCLIVALQNNQLKQKKWLVLSGIFFGASTAIKWNGLGFLLGIYLLWILVWIIKFFIQQKKYEYTSAWQNLTRINLIQLILNLFIIPIITYSLLWIPHIILNPKYGFLEMQEQIFSYHQRIGSGADIHPYCAQWFTWPLMMRPVVYFYKNTGLLDKPEPSLATLYSDIISPQLNPIIFDVHAMGNPILWWFSTWGILLLILMLFNRVWHWEKNRQARRKKIKLNHLFKFPPPSEMWLLLYLVINWLSNFMPWSRVSRCTFLYHYMGALVFAILGFSWCLDRWLNSQQASLRIMGVTMIFIVLFAFVFWMPIYLGLPLSPQNWQFRMWFRSWI
>NC_008312.1|WP_011610674.1|1399968_1400772_+|thermonuclease-family-protein
MKEIIKNILTNLGQVKLPAPSYFDSLETYTVKKVSDADTFNVVANGSEVEMTVRFVYIDTPETPKGWGDSQVEKMNHKNKNPIYRSQFEWGEKGKDRLQELVQKSDNQVKVKVTGEENRPGRSPRCFGEVYLLDGTFVQHILVKEGLARVYYDYISECPREIAIMLFLAEADAEINQRGIWQELQSEFMAPWVFRSLKKKQKNFLKDIGKELKAGSINEAEFEAKFELKLQQQNQILSILQKELISGLITQAKFEDKCKEELNHLFA
>NC_008312.1|WP_011610675.1|1401368_1402571_-|argininosuccinate-synthase
MSRATKVVLAYSGGVDTSVCIPYLKNEWGVKEVITLAADLGQGDELEGVRKKALDSGAVESLVIDVIEPLIKEYAFPAIQANALYENRYPLATALARPLIAKILVEAAEKYGADAIAHGCTGKGNDQVRFDVAIAALNPQIKILAPAREWGMSREETIAYGEEYGIPAPVKKSSPYSIDKNLLGMAIEAGELEDPWVEPPEEVYGMTKAIADTPNEPEYIEIGFERGIPVSLNGQEMGGIELITKLNQIAGNHGIGRIDMIENRLVGIKSREIYESPAMWVLIQGHRDLESLTLTADVTRYKRGIEETYSQLVYNGLWFSPLKGALDAFIQQTQERVTGVVRVKLFKGNAMVVGRKSDNSLYSFDLATYGAEDEFDHKAAEGFIYVWGLPTRVWSEKLRG
>NC_008312.1|WP_011610676.1|1403155_1404088_+|glycosyltransferase
MFFSIIIPTYNRLGILEKCLRALESQTYEQHITEYEVIVVDDGSTDDTIPWLKANATEFPHLQLWPQSHQGPAAARNLGVEVARGNFIIFIDSDLVVTDNFLQAHANTLIKYGKKSNCIFTYGRVINTCNFDFPTLEPLKLTDFSAAFFATGNVAIARHWLIEAGLFDTNFNQYGWEDLELGIRLKKLGLKLIKCSEAVGYHWHPPFSLEQLPRMIDREIQRGKMGVLFYQKHPILEVKIMIQMTYFHKLLWGVLSLGGRLNEKTMAVFLQWLIDRGKSQLALEISRIFLNWYNVKAVYSAYANIDGFRK
>NC_008312.1|WP_011610677.1|1404360_1404582_+|hypothetical-protein
MIEPDFPHIILTFEYKGWKVEIDQGEMNGSATYAVWANYNNGCVVAVPLASSRQEAVRRAKQWINTRNKKNKT
>NC_008312.1|WP_011610678.1|1406489_1407422_+|methyltransferase-domain-containing-protein
MANNMVASDLWISEHITPWDIYVHGLTKVLAYKKTAYQEMYIVETGIYGKALVLDGKWQSCTGDEFLYHEPLVHPAMICHGSPRKVLVLGGGEGATIREVFRWQSVEKVAMVDIDGEVVEACRQYLPEMHANAFDDPRLQLVIGDALKFLETFGESWDVVISDLSDPIEEGPSFQLFTKEYFEKILRVLTPGGFFVVQAGPVSPGEMKLHARIVNTMKAVFPFVQSYNSNIPTYGRPWGFALGSRKMVNSRPEPEMIDKLLKEKTIGGFRMLDGTTLLGMLQVPLHLREAIATETKIYTLAEPPKFGRPA
>NC_008312.1|WP_011610679.1|1407783_1407951_+|YqaE/Pmp3-family-membrane-protein
MSILRILAAIFLPPLGVFLTVGLGGAFWINLLLTIFGFYIAGIVHAIWVIAKHDN
>NC_008312.1|WP_011610680.1|1408254_1408719_+|TM2-domain-containing-protein
MKGIILAVSIQKGNGIISGDDGKRYRFLLSSWYAEQNPKQGLRVDFDTTPEGEALDIYQDISDISASPSSQLNPKNRGIAAILAFFLGAFGAHKFYLGYSQAAIIMLIVSLVGSFLVIPTLVMSIIAFIEFITYLTKSDQEFYDTYLKNKKAWF
>NC_008312.1|WP_011610681.1|1409260_1410328_+|branched-chain-amino-acid-aminotransferase
MQIVNSQISIEKTSHSRIKEQDINNTPFGKVFSDHMLVATYANNSWQEVKITPYGNISIRPSLSVLHYGQAVFEGLKAYKNYQGKPVLFRLEANYKRINNSAFRLCMPSIPKEIFIDGLKELIRLDTDWIPTKSDSALYIRPIYFATDESVGLKPANSYKFIILSSPTGTFYSAPVKLIVTDKYVRASEGGTGAAKCAGNYAGSFLADKEAKEQGYDNVLWLDGKEKKYIEECGTMNVAFVINDVLITPKLTGSILGGITRDSALTLFRDMGVKVEERLISIDEVAKAYEAGNISEAFGMGTAATIAHISVINYQGKDMILPPVDERKYASQVLQKLEDIKTGKVTDPYGWICQL
>NC_008312.1|WP_011610682.1|1410905_1411763_+|hypothetical-protein
MIKQGSFKSILSIFKAPAGLIAGSTYHFRALIIFVKNPRLINYIIAPIFINIVVGIFLYISLLLPGISLINTIFNNLSLQFDSLIYQLPTWLKFLSYLDNALGLLFKLILFTIFLLIIGFLLVQFGVILGSPFYGQLSEQLEKTRTGTLPEASSGLLSIIRDIYRAILFELKKVALLLAIGLPMLLLNFFPGGSLIATIGGIALTTSIVCLDFFDGPLERRKLKFREKLKVVYRSLPASATFGLICQVLITIPIVNFLAIPICVVAGTLFCCDRVLPKLLPNNQT
>NC_008312.1|WP_044137173.1|1412247_1412706_+|superoxide-dismutase,-Ni
MLNTIATQIRKWFSAPEVSAHCDGPCGVYDPASARIYAEAVLSMTKKILDLDPKAGDHKTANTLSRYIAIKEEQAQKTKEDLLILWTDYFKPVHLEKYPDLHDTFWKAAKLCSACKVEVSLEHATELLAAVEKIHNMFWATKERDVTWYKAS

Crispr_ID: NC_008312_11

• CRISPR_ID: NC_008312_11
• CRISPR_location: 1511014-1511160
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NC_008312_11

Consensus_repeat	Method
CTACCACTAAAATATTTTCACCATTTACTCTGTAGGTCATTTAGTCAATCA	CRISPRCasFinder

spacers of NC_008312_11

>11.1|1511065|45|NC_008312|CRISPRCasFinder
GCGGTTGGGTGTTGCTAGTCAAGTACACCAATTGAGATTATAGTC

CRISPR arrays and Neighbor proteins around NC_008312_11

CRISPR arrays

The CRISPR arrays of NC_008312_11

>merge|NC_008312|11|1511014-1511160|CRISPRCasFinder
CTACCACTAAAATATTTTCACCATTTACTCTGTAGGTCATTTAGTCAATCAGCGGTTGGGTGTTGCTAGTCAAGTACACCAATTGAGATTATAGTCCTACCACTAAAATATTTTCACCATTTACTCTGTAGGTCATTTACTCAATCA

>NC_008312|11|9|1511014-1511160|CRISPRCasFinder
CTACCACTAAAATATTTTCACCATTTACTCTGTAGGTCATTTAGTCAATCA	GCGGTTGGGTGTTGCTAGTCAAGTACACCAATTGAGATTATAGTC
CTACCACTAAAATATTTTCACCATTTACTCTGTAGGTCATTTACTCAATCA

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_008312.1|WP_011610732.1|1503513_1504245_-|response-regulator-transcription-factor	unknown	unknown	gnl|CDD|214376
NC_008312.1|WP_011610740.1|1525248_1525980_+|GTP-cyclohydrolase-I-FolE	unknown	unknown	gnl|CDD|236472
NC_008312.1|WP_011610731.1|1502662_1503307_-|cofactor-assembly-of-complex-C-subunit-B	unknown	unknown	gnl|CDD|371397
NC_008312.1|WP_011610738.1|1519888_1521130_+|insulinase-family-protein	unknown	unknown	gnl|CDD|223685
NC_008312.1|WP_011610733.1|1505692_1507246_+|DNA-repair-protein-RadA	unknown	unknown	gnl|CDD|236994
NC_008312.1|WP_081432524.1|1493240_1493435_-|hypothetical-protein	unknown	unknown	gnl|CDD|372648
NC_008312.1|WP_044136413.1|1509380_1510463_-|dTDP-glucose-4,6-dehydratase	unknown	unknown	gnl|CDD|224013
NC_008312.1|WP_011610726.1|1491214_1491544_-|thioredoxin	unknown	unknown	gnl|CDD|365862
NC_008312.1|WP_011610743.1|1534515_1535817_-|FGGY-family-carbohydrate-kinase	unknown	unknown	gnl|CDD|223996
NC_008312.1|WP_081432525.1|1512047_1513337_+|CapA-family-protein	unknown	unknown	gnl|CDD|214858
NC_008312.1|WP_011610728.1|1496537_1497833_+|glutamyl-tRNA-reductase	unknown	unknown	gnl|CDD|234592
NC_008312.1|WP_011610737.1|1518213_1518468_-|hypothetical-protein	unknown	unknown	gnl|CDD|227226
NC_008312.1|WP_052845744.1|1517231_1517708_-|hypothetical-protein	unknown	unknown	gnl|CDD|227226
NC_008312.1|WP_011610729.1|1498059_1499565_+|hypothetical-protein	unknown	unknown	gnl|CDD|334588
NC_008312.1|WP_011610730.1|1501446_1501731_+|hypothetical-protein	unknown	unknown	unknown
NC_008312.1|WP_011610739.1|1522900_1523875_+|acetyl-CoA-carboxylase-carboxyl-transferase-subunit-alpha	unknown	unknown	gnl|CDD|235580
NC_008312.1|WP_011610742.1|1531675_1533391_+|HAMP-domain-containing-histidine-kinase	unknown	unknown	gnl|CDD|223715
NC_008312.1|WP_011610727.1|1494751_1495789_+|class-II-fructose-bisphosphatase	unknown	unknown	gnl|CDD|236536
NC_008312.1|WP_011610736.1|1514702_1515035_-|hypothetical-protein	unknown	unknown	gnl|CDD|380119
NC_008312.1|WP_011610741.1|1527064_1528504_+|phosphoglucomutase/phosphomannomutase-family-protein	unknown	unknown	gnl|CDD|100093

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_008312.1|WP_011610732.1|1503513_1504245_-|response-regulator-transcription-factor	gnl|CDD|214376	CHL00148, orf27, Ycf27; Reviewed.	2.07111e-154
NC_008312.1|WP_011610740.1|1525248_1525980_+|GTP-cyclohydrolase-I-FolE	gnl|CDD|236472	PRK09347, folE, GTP cyclohydrolase I; Provisional.	1.88685e-118
NC_008312.1|WP_011610731.1|1502662_1503307_-|cofactor-assembly-of-complex-C-subunit-B	gnl|CDD|371397	pfam11152, CCB2_CCB4, Cofactor assembly of complex C subunit B, CCB2/CCB4. Cofactor maturation pathways such as the CCB system (system IV) for cytochrome c-heme attachment are conserved in all organisms performing oxygenic photosynthesis. The CCB system consists of four proteins: CCB1-4. CCB2 and CCB4 are paralogues derived from a unique cyanobacterial ancestor. Orthologues are conserved in higher plants.	4.57019e-109
NC_008312.1|WP_011610738.1|1519888_1521130_+|insulinase-family-protein	gnl|CDD|223685	COG0612, PqqL, Predicted Zn-dependent peptidases [General function prediction only].	1.54514e-102
NC_008312.1|WP_011610733.1|1505692_1507246_+|DNA-repair-protein-RadA	gnl|CDD|236994	PRK11823, PRK11823, DNA repair protein RadA; Provisional.	0
NC_008312.1|WP_081432524.1|1493240_1493435_-|hypothetical-protein	gnl|CDD|372648	pfam13612, DDE_Tnp_1_3, Transposase DDE domain. Transposase proteins are necessary for efficient DNA transposition. This domain is a member of the DDE superfamily, which contains three carboxylate residues that are believed to be responsible for coordinating metal ions needed for catalysis. The catalytic activity of this enzyme involves DNA cleavage at a specific site followed by a strand transfer reaction.	2.21243e-12
NC_008312.1|WP_044136413.1|1509380_1510463_-|dTDP-glucose-4,6-dehydratase	gnl|CDD|224013	COG1088, RfbB, dTDP-D-glucose 4,6-dehydratase [Cell envelope biogenesis, outer membrane].	0
NC_008312.1|WP_011610726.1|1491214_1491544_-|thioredoxin	gnl|CDD|365862	pfam00085, Thioredoxin, Thioredoxin. Thioredoxins are small enzymes that participate in redox reactions, via the reversible oxidation of an active centre disulfide bond. Some members with only the active site are not separated from the noise.	7.10155e-35
NC_008312.1|WP_011610743.1|1534515_1535817_-|FGGY-family-carbohydrate-kinase	gnl|CDD|223996	COG1070, XylB, Sugar (pentulose and hexulose) kinases [Carbohydrate transport and metabolism].	6.20885e-77
NC_008312.1|WP_081432525.1|1512047_1513337_+|CapA-family-protein	gnl|CDD|214858	smart00854, PGA_cap, Bacterial capsule synthesis protein PGA_cap. This protein is a putative poly-gamma-glutamate capsule biosynthesis protein found in bacteria. Poly-gamma-glutamate is a natural polymer that may be involved in virulence and may help bacteria survive in high salt concentrations. It is a surface-associated protein.	2.17431e-73
NC_008312.1|WP_011610728.1|1496537_1497833_+|glutamyl-tRNA-reductase	gnl|CDD|234592	PRK00045, hemA, glutamyl-tRNA reductase; Reviewed.	0
NC_008312.1|WP_011610737.1|1518213_1518468_-|hypothetical-protein	gnl|CDD|227226	COG4889, COG4889, Predicted helicase [General function prediction only].	1.40679e-13
NC_008312.1|WP_052845744.1|1517231_1517708_-|hypothetical-protein	gnl|CDD|227226	COG4889, COG4889, Predicted helicase [General function prediction only].	3.16637e-12
NC_008312.1|WP_011610729.1|1498059_1499565_+|hypothetical-protein	gnl|CDD|334588	pfam01555, N6_N4_Mtase, DNA methylase. Members of this family are DNA methylases. The family contains both N-4 cytosine-specific DNA methylases and N-6 Adenine-specific DNA methylases.	1.18543e-10
NC_008312.1|WP_011610739.1|1522900_1523875_+|acetyl-CoA-carboxylase-carboxyl-transferase-subunit-alpha	gnl|CDD|235580	PRK05724, PRK05724, acetyl-CoA carboxylase carboxyltransferase subunit alpha; Validated.	0
NC_008312.1|WP_011610742.1|1531675_1533391_+|HAMP-domain-containing-histidine-kinase	gnl|CDD|223715	COG0642, BaeS, Signal transduction histidine kinase [Signal transduction mechanisms].	5.04369e-18
NC_008312.1|WP_011610727.1|1494751_1495789_+|class-II-fructose-bisphosphatase	gnl|CDD|236536	PRK09479, glpX, fructose 1,6-bisphosphatase II; Reviewed.	0
NC_008312.1|WP_011610736.1|1514702_1515035_-|hypothetical-protein	gnl|CDD|380119	pfam18135, Type_ISP_C, Type ISP C-terminal specificity domain. This is the C-terminal domain of Type ISP restriction-modification enzyme LLaBIII present in Lactococcus lactis subsp. cremoris. Type ISP restriction-modification (RM) enzymes provide a potent defence against infection by foreign and bacteriophage DNA. This domain interacts extensively with DNA and is known as the target recognition domain (TRD). TRD works by recognising 6/7 base pairs of asymmetric sequence.	3.03025e-19
NC_008312.1|WP_011610741.1|1527064_1528504_+|phosphoglucomutase/phosphomannomutase-family-protein	gnl|CDD|100093	cd05800, PGM_like2, This PGM-like (phosphoglucomutase-like) protein of unknown function belongs to the alpha-D-phosphohexomutase superfamily and is found in both archaea and bacteria. The alpha-D-phosphohexomutases include several related enzymes that catalyze a reversible intramolecular phosphoryl transfer on their sugar substrates. Other members of this superfamily include phosphoglucosamine mutase (PNGM), phosphoacetylglucosamine mutase (PAGM), the bacterial phosphomannomutase ManB, the bacterial phosphoglucosamine mutase GlmM, and the bifunctional phosphomannomutase/phosphoglucomutase (PMM/PGM). Each of these enzymes has four structural domains (subdomains) with a centrally located active site formed by four loops, one from each subdomain. All four subdomains are included in this alignment model.	0

Protein sequences

>NC_008312.1|WP_044136413.1|1509380_1510463_-|dTDP-glucose-4,6-dehydratase
MKIMETRLLITGGAGFIGSNFTHYWCQTYPNHRVVVLDALTYAGNKKTLADLQDRSNFRFVQGDICDRSLVDSLLQEEDIDTVAHLAAESHVDRSILGPAAFVQTNVVGTFTLLEAFRSHYQTLAQNPDRKCIFLHVSTDEVYGSLSPQELAFTETTPYSPNSPYSASKAGSDHFARAYYHTYGVPTIITNCSNNYGPYHFPEKLIPLMCINILLGKELPVYGDGQNIRDWLYVIDHCRALDTVIHKGKPGQTYNVGGNNEVKNINLVQMLCQIMDELANDLPVKPCEKLITFVKDRPGHDRRYAIDATKIKTELGWQPSVTVEEGLRQTVKWFLNNRDWWEPLLSEEYQAYYKQVYSSS
>NC_008312.1|WP_011610733.1|1505692_1507246_+|DNA-repair-protein-RadA
MPKHKTKYVCRECGYESTQFLGRCPGCNTWNSLKEEIEQTTVTALQRLGITDIGIGSQASEGDDSSGQPRASFLLSQISDQTLSRMPSGFEELDRVLGGGIVPGSLVLIGGEPGIGKSTLLLQVANQLSNRCRVLYVSAEESGQQVKLRSQRLIVNFNEAKVEHKDNVSNVEIDQDLSNDENQENYGNSEPINDSTTDSMENLFLLPETDLEVILRELESLKPYLAVIDSIQTIYFASLTSAPGSVAQVRECTSALMQVAKRENITLLIVGHVTKDGALAGPRVLEHLVDTVLYFEGDRFASHRLLRSMKNRFGATHEIGVFEMVANGLKEILNPSELFLGSRDEYSSGTSTVVSMEGTRPIVVEIQALVSPASHGSPRRSTTGIDGSRLQQILAVLEKRVGIPLSKLDTYVATVGGLSVEEPAADLGIAIAVVASFRDRVVDPRTVLLGEVGLGGQVRPVSQLELRLREAAKLGFKRAIIPKGQQPMDLGMRILPIAKVIDAIIAAIPAQPPTMEN
>NC_008312.1|WP_011610732.1|1503513_1504245_-|response-regulator-transcription-factor
MEYNKEKILVVDDEASIRRILETRLSMIGYDVVTAADGEEALETFHNTTPDLVVLDVMMPKLDGYGVCQELRKESDIPIIMLTALGDVADRITGLELGADDYVVKPFSPKELEARIRSVLRRVDKNGGNGIPSSGVIQVSTIRIDTNKRQVYKGDERIRLTGMEFSLLELLVSRSGEPFSRSEILQEVWGYTPERHVDTRVVDVHISRLRAKLEEDPSNPELILTARGTGYLFQRIIERDEVG
>NC_008312.1|WP_011610731.1|1502662_1503307_-|cofactor-assembly-of-complex-C-subunit-B
MSQSDQNKVLRMLPIIAGGLGATLLMTNRFFTPNLLASQTRSDVVGVILSAFLILTGLLWQQIQPRSPDTVKLIGKSEFELLPELSEIVKTELAWASSLLLTNTVTKTVIIWHQEKVLLRRGILPSESYIKPGTILKQVLGKQKPIYLVDLKVYPGRIEFNYLPENTQGVICQPLGNNGVMILGANAPRSYTKQDENWISGIADKLTDTLSKKL
>NC_008312.1|WP_011610730.1|1501446_1501731_+|hypothetical-protein
MKNKTLSDIRQEYKGLYFKTISNKKRFYSLLSTLKRIFKIGLFVAETYFHFILLPNLWLSRDFSQDKQKVYLSRQGNWLHKKFLTMGAVFIKAR
>NC_008312.1|WP_011610729.1|1498059_1499565_+|hypothetical-protein
MTDKNNLPKQLSLFNLNSTNIEDLATPKGYKGIAAFHKYWGKKPIECLSFLIESLTTENDIILDPFLGSGLVARESISRKRRFIGIDINPISVELAKMLIDLPSHLHLREILSSFEENIKPKIEATYTLDDGNIASHYLWEEEKIKSVWTIAKGGRKREERIPTEYDYNLIEQFQNYQPKIPREINLFQNSRINTKDNFKLTDLLTCRALHNIDILLEAINQQDNELKKALLLSLTSASGQMSKMVFAITGRGKNKNQPTKKIEVGSWVIGYWRPTLHFEINVWNCFERRVKKLIKAIDEIDDINTSNLSGQLIDVVNYKANVAIVEGDNRKVLSECPDEIISLIVADPPHSDRIPYLELSEMWNSLIGKKPNFSDEIVISNAVIRGKDRKTYIKEMGIFFDNTARILKPGGILALFFNSKDREIWNFLNQIILSSTEINFRGYFPMKYSSNSVLQNNRTGSLKHDFVLIYQKSGKRSSEFFQSLIVIPGWRSEFPNYADN
>NC_008312.1|WP_011610728.1|1496537_1497833_+|glutamyl-tRNA-reductase
MNIAVIGLSHKTAPVEVREKLSLPETEIQNAISELCSGTYTQEVGILSTCNRLEIYVVTNEMQPGIREVTQFLSESSKIPLNQLRPHLFMLLHEDSIMHLMRVASGLDSLVLGEGQILAQVKQTHKLGQKYKGIGRILNRLFKQAVTAGKRVRTETSIGTGAVSVSSAAVELAQMKLEDLSNYQVAIVGAGKMSKLLVQHLLAKGANKISIINRSVGRAQDLANSFKDANIKVYSMLEMVQVIGESDLVFTSTAATELILDKAKLETILDPLKPLMLVDISVPRNIGNDVSELPNVRCFNVDDLKAVVAQNRESRRQMAMEAEVLLEEEVEAFDVWWKSLETVPTINSLRQKIETIREQELEKALSRLGSEFAEKHQEVIEALTRGIVNKILHDPMVQLRAQQDIEARRHAMETLQLLFNLESEMSSGKVI
>NC_008312.1|WP_011610727.1|1494751_1495789_+|class-II-fructose-bisphosphatase
MDNVIGLEIIEVVEQAAIASARWMGKGEKNTADEVAVEAMRERMNKIHMRGRIVIGEGERDEAPMLYIGEEVGICTQPDAKKMCEVEQLIEIDIAVDPCEGTNLVAYGQNGSMAVLAISEKGGLLAAPDVYMKKLAAPAVAKNHVDINKSATENLKIISECMDRAVEELVVVVMDRPRHKQLISEIRQAGARVRLISDGDVSAAISCAFAGTNIHALMGIGAAPEGVISAAAMRALGGHFQGQLIYDPAIVKTGLIGESKEDNMKRLKDMGIEDPDKVYNAEELASGETVLFAACGITPGTLMEGVRFFPNGARTQSLVISSQSKTARFVDTVHMFGETKTLQLK
>NC_008312.1|WP_081432524.1|1493240_1493435_-|hypothetical-protein
MSLDEAKKLHFYLKFISKKKGNLFGDKGYISQNLFDKLYGNNLILVTLYQKNMKNKLVDLWKKN
>NC_008312.1|WP_011610726.1|1491214_1491544_-|thioredoxin
MSSNVVVITDSEFEGEVLQSEKLVLAYFWASWCGPCKLVSPSVEKVATTYSDRLKVVKMEVDPNPETVKSYKVEGVPALRLFGNKKLLLSHEGSITLNKLVERLEAHLA
>NC_008312.1|WP_081432525.1|1512047_1513337_+|CapA-family-protein
MERQYSKNKNKFIWILASAISILLLPISTVVINSQTDRINPIISKIFLLPKISHLNTSEVEVSNSVPASISTRNTRQSIETKPTKSQLNLSEVFEFILSSIKSPINPDTRITIKAVGDIIPGTNYPQNKLHPRKQELLASVKPLLQNADLVFGNFESTLTNYPKSRKRMGNGRVFAFRTPPDYRNLLKDAGFNILSVANNHSFDFFKQGFEDTIANIKTVGMQAVGKKGEIVYRKVKGINIGFIAFSNYSYHNSMLDLYSAKKLVQEADKNADIVVISVHAGAEGTRALRIKNKTEYFFGENRGNKVLFAHKLIDEGADLILGHGPHVPRAMEIYQGKLIAYSLGNFMGYRTLSSKGKLGYSLVLELDINIRGDFISGKILPVHLNSKGIPYPDKLGRSIKLIKELTQKDFPKTMLEINSKGEITRKKG
>NC_008312.1|WP_011610736.1|1514702_1515035_-|hypothetical-protein
MTRINLPTPDNFPTPKTKFKVDKNNHKIFIDTLTILEKIPKIAWEYCLGNRSALEWVLDQYKEKKSKDKTITEKFDTYCFANYKETVIDLLQKVDNVSVETMKIIQIMET
>NC_008312.1|WP_052845744.1|1517231_1517708_-|hypothetical-protein
MTGIVVSFLLKDGQEKTVGNLIYYSHLFPMHELRENKFQFLAATKFSKIDFENIQADKNNNWINLTDNDFNNLLPIADKNTRLAKSKTGEIAIFKVFILGIATNRDEWLYDFDRQQLAEKVQFFCKFYEQKRVRWNQSNNKTVINDFFDRKIKYTSEL
>NC_008312.1|WP_011610737.1|1518213_1518468_-|hypothetical-protein
MIESVDYLADKNFGKLLCDSGVKILEIATGTSTFVTDLIEYLPKNKLEYKYQNNIFCNEVAILPYYIGNFNIEYTYQQKIGSYE
>NC_008312.1|WP_011610738.1|1519888_1521130_+|insulinase-family-protein
MINQTNINRTVLNNGIVVITAENTVADIVSAKIFLGIGSSYEAKNQAGISHLLAAVLTKGTKKLSSLDIALKIESVGARLGSDTTADYFLLSIKTVSEDFNDIFQLSGEIIRCPSFPETEIELEKRITIQSIRSQLEQPFTVAFSQLREMMYQDHPYALSTLGTENTVSQITRYDIQKFYETYFRPDNIVISIVGKISNAKAIALVEQIYGDWQPPRTLLPTLNLPRITPQPFTAKKYQETQQSIIMLGYLAANVNSSDYAPLKLLNTYLGNGLSSRLFVELREKRGLAYDVSAFYPTRLYTSNFTVYIGTAGENTAIAKAGLKSEIERLVTELLSEEELEISKNKLLGQYALGKQTNSQIAQILGWYEILNLGIDFDAKFQKNLEMVTTLDTQKVAIKYFIEPYISIVGKEK
>NC_008312.1|WP_011610739.1|1522900_1523875_+|acetyl-CoA-carboxylase-carboxyl-transferase-subunit-alpha
MPKSERKILLDFEKPLAELENRINQIRELAKDCSSVDVSEQIYQLEAKATQLRQEIFSSLSPVQKLQLARHPRRPTSLDYIQAISDEWIELHGDRGGSDDPAIVGGLARVNGRPVVIIGHQKGRDTKDNVARNFGMASAGGYRKSIRFMEHGNRFGMPILTFIDTPGAWPGIEAERLGQGEAIAYNLREMFHLDVPIICTVIGEGGSGGALGVGVGDRLLMLEHSIYTVASPEACAAILWKDASKASQAAEALKITSWDLKKIGIIDDVVPEPSGGAHANPLQAAENLKTAIVKSLDDLNHLSSPQRRKKRYQKFRSMGVFLET
>NC_008312.1|WP_011610740.1|1525248_1525980_+|GTP-cyclohydrolase-I-FolE
MTQSSSNRSNSKNTLNMNGVKTSDANMTSQISYRPERISSSNGQSIKQKLSTEDSNERMKEAVRTILLSVEENPEREGLLNTPKRFAEAMQFLTSGYSQSLEEIVNGAIFDEGHNEMVLVRDINFFSLCEHHMLPFMGKAHIAYIPNQKVVGLSKLARVVDMYSRRLQVQERLNRQIAEAIQTILEPKGVAVVIEATHISMVMRGVQKPGSWTVTSAMVGLFKEDQKTREEYLNLIRHQPTFF
>NC_008312.1|WP_011610741.1|1527064_1528504_+|phosphoglucomutase/phosphomannomutase-family-protein
MAKPIKFGTDGWRGVIADDFTFERVTLVAPIAAKILDKNYADSTNNSKTIIVGHDRRFMAEEFAQVAAEAIQNAGFDVLLTDTYAPTPAFSLAAFQKKALGAIVMTASHNPGKYLGLKVKGAFGGSVPPEITKQIEDLLTVETEKNLVQEGKIETFNPWQNYCETLKKMVEIHSIKSAINEGKLKVFADVMHGAAAGGLQQILGVEIEEVNGNRDPFFDGGAPEPLPRYLSKLFKRIKSYRAANEGSLAIGLVFDGDSDRIAAVDGEGNFLSSQILIPILIEHLTTTHGCSGEVVKTISGSDLFPKVAELYKMPVFETPIGYKYIADRMLSTQVLVGGEESGGIGYGTHIPERDALLSALYLLEAVVMSSEDLTTIYRHLQEKTGFSSVYDRIDLPLLNMGVRSRLLEELINNPVTEVAGQKVLDCITIDGYKFRLADGRWLLIRFSGTEPVLRLYCEATDMQKVKQTLEWAKNWANSI
>NC_008312.1|WP_011610742.1|1531675_1533391_+|HAMP-domain-containing-histidine-kinase
MDNYILPTLSDIFASEKSNIDVYATKMELSKENYPPSITEKNKDLYLKAQKEWYSAVATINQLLEKLVRTSDSQDLKNQEITKTYKQKEIKKTTPVLENWESQTRSKFPTSNSLLSHLKSYHGLVLSGMTPVLTNPALTSSFYTSVFTSKISESLEWLSMFRWQSLPLLPPADHINSLPAAIPILPLSTKDPITNEQFCLVLTAEFSLIMVLGKNQDNTPAFLFSFEPEIVKKAWLVLQQRRVLPKYFDFNNLDKYQSFIHQYSQKLAILDDIFEQFLPVAPDYKIVMEFSRLLLSNLPITDTKNETLEVNIYNKNGEKQEATTSLKSTIENLKSPDVELLQAIAHEVKTPLATIQTLTRLLLKRLNLNQELMRKHLQMIDTECTSQIERFNLIFRAAELENQQPLKEQHPYLQLTSIPLAQVFKNSIPRWQQKATQRNHTLKVILPPKMPSIISDPTMLDQVLGNLIENFSRNLAPGSLIKVEVMLAGSQLKLQLKSDSDIGEKSSSPFTNYTKTPLKSIGPLLMFQPETGSLSLNLKVTKNLFQAIGGKLVVRQRPTKGEVMTIFLPVQ
>NC_008312.1|WP_011610743.1|1534515_1535817_-|FGGY-family-carbohydrate-kinase
MNLYLGIDFGTSGARAVVIDSNFRVKAQTKYIWETEENKLPHVWQKALFNLISNIPQEIRRKIRAIAIDGTSATVLLCNSDGKPVTETLLYNDSRGVTMMNKLKSIAPSNHSVISVTSSFAKLLWLTENTSTLNQNQTYYFLHQADWLGFLLHGKLGVSDYNNVLKLGYDVNDLCYPDWLNNFVNSEVGKNIQLPEVVKPGATVDSVTTEIVNNFGLSPECVVCGGTTDSIAAFIASGANSPGEAVTSLGSTLVLKLLSHTRVDNSKYGIYSHRFGNLWLVGGASNTGGAVLRHFFTEAELESLSRQIDPNIESRLDYYPLLEKGDRFPINDPELLPKLAPRPENSILFLHGLLEGIAKIELRGYELLQALSADTLTKVYTAGGGAKNSTFTTIRGRYLGVPTIKAVYTDAAYGSAILATHQFISDQTNLTGL

Crispr_ID: NC_008312_12

• CRISPR_ID: NC_008312_12
• CRISPR_location: 1606273-1607292
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 14 spacers

Consensus repeat of NC_008312_12

Consensus_repeat	Method
TTTTTNANTTATNAGCTTTT	CRT

spacers of NC_008312_12

>12.1|1606293|78|NC_008312|CRT
CAATTATCAGTTTTTTGATTTATTAGTATTAGTACCTCCAGTTAAAACTTCAGTTCAGAGTTTTTTTCAGTTATAAGT
>12.2|1606391|79|NC_008312|CRT
TTAGTTATTAGCTATTAGTATCTCAAATTCAAGCTTCAATTATCAGCTTTTTCATTTCTTAGCTTTTTCATTTCTTAGC
>12.3|1606490|64|NC_008312|CRT
TCAGTTATCAGCTTTTTGATTTATTAGCTATTAGTACCTCCGATCCAAGCTTTAATTATCAGTT
>12.4|1606574|49|NC_008312|CRT
TCAGTTATCATTTATCAGTTATCAATTATCAGTTTTTTCAGTTATCAGC
>12.5|1606643|32|NC_008312|CRT
AGTACCTCCGATCCAAGCTTTAATTATCAGTT
>12.6|1606695|47|NC_008312|CRT
AGTTATCATTTATCAGTTATCATTTATCAGTTTTTTCAGTTATCAGC
>12.7|1606762|31|NC_008312|CRT
AGTACCTCCAGTTCAAGCTTCAGTTATCAAC
>12.8|1606813|65|NC_008312|CRT
AGTACCTTCAGTTCAAGCTTTAATTATCAGTTTTTTTTCAGTTATTAACTTTTTCAGTTATCAGC
>12.9|1606898|49|NC_008312|CRT
TTAGTTGTTAGCTATTACTACCTCCATTTCAAGCTTTAATCATCAGTTT
>12.10|1606967|47|NC_008312|CRT
TCAGTTATCAGCTTTTTGATTTATTAGTTATGAGTACCTTCAGTTAA
>12.11|1607034|44|NC_008312|CRT
TCAGTTCTTATATTTTTCAGTTCTTAGCCTTTTTAGTCATCAAC
>12.12|1607098|60|NC_008312|CRT
TTAGTTATTAGTTATTAGCACCTCCAGTTAAAGCTTCATTTATAACTCAGTTATTAACCT
>12.13|1607178|48|NC_008312|CRT
TTAGTTATTAGCTATTAGTAACTTCAGTTTAAGCTTCAATCATCAGCT
>12.14|1607246|27|NC_008312|CRT
TCAATTATTGGCTTTTTTAGTTATCAG

CRISPR arrays and Neighbor proteins around NC_008312_12

CRISPR arrays

The CRISPR arrays of NC_008312_12

>merge|NC_008312|12|1606273-1607292|CRT
TTTTTCAGTTATCAGTTTTCCAATTATCAGTTTTTTGATTTATTAGTATTAGTACCTCCAGTTAAAACTTCAGTTCAGAGTTTTTTTCAGTTATAAGTTTTTTCAGTTATCAGCTTTTTTAGTTATTAGCTATTAGTATCTCAAATTCAAGCTTCAATTATCAGCTTTTTCATTTCTTAGCTTTTTCATTTCTTAGCTTTTTCAGTTATCAGCTTTTTCAGTTATCAGCTTTTTGATTTATTAGCTATTAGTACCTCCGATCCAAGCTTTAATTATCAGTTTTTTTCAGTTCTTAGTTTTTTCAGTTATCATTTATCAGTTATCAATTATCAGTTTTTTCAGTTATCAGCTTTTTGATTTATTAGCTATTAGTACCTCCGATCCAAGCTTTAATTATCAGTTTTTTTCAGTTATTATTTATCAGTTATCATTTATCAGTTATCATTTATCAGTTTTTTCAGTTATCAGCTTTTTGATTTATTAGCTATTAGTACCTCCAGTTCAAGCTTCAGTTATCAACTTTTTTAGTTGTGAGCTATTAGTACCTTCAGTTCAAGCTTTAATTATCAGTTTTTTTTCAGTTATTAACTTTTTCAGTTATCAGCTTTTTCAGTTATCAGCTTTTTTAGTTGTTAGCTATTACTACCTCCATTTCAAGCTTTAATCATCAGTTTTTTTTCAGTTATCAGCTTTTTCAGTTATCAGCTTTTTGATTTATTAGTTATGAGTACCTTCAGTTAAAGCTTCAATTATCAGCTTTTTCAGTTCTTATATTTTTCAGTTCTTAGCCTTTTTAGTCATCAACTTTTTCAGTCATCAGCTTTTTTAGTTATTAGTTATTAGCACCTCCAGTTAAAGCTTCATTTATAACTCAGTTATTAACCTTTTTTTACTTATAATCTTTTTTAGTTATTAGCTATTAGTAACTTCAGTTTAAGCTTCAATCATCAGCTTTTTTTAGCTATTAAATTTTTCAATTATTGGCTTTTTTAGTTATCAGTTTTTCAAGGGTTAACTTTT

>NC_008312|12|4|1606273-1607292|CRT
TTTTTCAGTTATCAGTTTTC	CAATTATCAGTTTTTTGATTTATTAGTATTAGTACCTCCAGTTAAAACTTCAGTTCAGAGTTTTTTTCAGTTATAAGT
TTTTTCAGTTATCAGCTTTT	TTAGTTATTAGCTATTAGTATCTCAAATTCAAGCTTCAATTATCAGCTTTTTCATTTCTTAGCTTTTTCATTTCTTAGC
TTTTTCAGTTATCAGCTTTT	TCAGTTATCAGCTTTTTGATTTATTAGCTATTAGTACCTCCGATCCAAGCTTTAATTATCAGTT
TTTTTCAGTTCTTAGTTTTT	TCAGTTATCATTTATCAGTTATCAATTATCAGTTTTTTCAGTTATCAGC
TTTTTGATTTATTAGCTATT	AGTACCTCCGATCCAAGCTTTAATTATCAGTT
TTTTTCAGTTATTATTTATC	AGTTATCATTTATCAGTTATCATTTATCAGTTTTTTCAGTTATCAGC
TTTTTGATTTATTAGCTATT	AGTACCTCCAGTTCAAGCTTCAGTTATCAAC
TTTTTTAGTTGTGAGCTATT	AGTACCTTCAGTTCAAGCTTTAATTATCAGTTTTTTTTCAGTTATTAACTTTTTCAGTTATCAGC
TTTTTCAGTTATCAGCTTTT	TTAGTTGTTAGCTATTACTACCTCCATTTCAAGCTTTAATCATCAGTTT
TTTTTCAGTTATCAGCTTTT	TCAGTTATCAGCTTTTTGATTTATTAGTTATGAGTACCTTCAGTTAA
AGCTTCAATTATCAGCTTTT	TCAGTTCTTATATTTTTCAGTTCTTAGCCTTTTTAGTCATCAAC
TTTTTCAGTCATCAGCTTTT	TTAGTTATTAGTTATTAGCACCTCCAGTTAAAGCTTCATTTATAACTCAGTTATTAACCT
TTTTTTACTTATAATCTTTT	TTAGTTATTAGCTATTAGTAACTTCAGTTTAAGCTTCAATCATCAGCT
TTTTTTAGCTATTAAATTTT	TCAATTATTGGCTTTTTTAGTTATCAG
TTTTTCAAGGGTTAACTTTT

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_008312.1|WP_011610781.1|1585963_1586881_+|homoserine-kinase	unknown	unknown	gnl|CDD|234920
NC_008312.1|WP_155994310.1|1616567_1616738_-|hypothetical-protein	unknown	unknown	unknown
NC_008312.1|WP_011610784.1|1594182_1594482_-|hypothetical-protein	unknown	unknown	unknown
NC_008312.1|WP_155994311.1|1617907_1618084_+|hypothetical-protein	unknown	unknown	gnl|CDD|223704
NC_008312.1|WP_011610796.1|1625439_1627242_+|M61-family-metallopeptidase	unknown	unknown	gnl|CDD|226483
NC_008312.1|WP_011610787.1|1601166_1601847_+|HupE/UreJ-family-protein	unknown	unknown	gnl|CDD|368209
NC_008312.1|WP_044136428.1|1596120_1597305_+|aspartate-aminotransferase	unknown	unknown	gnl|CDD|180317
NC_008312.1|WP_011610792.1|1615166_1615469_+|diversity-generating-retroelement-protein-Avd	unknown	unknown	gnl|CDD|380307
NC_008312.1|WP_011610795.1|1624554_1625238_+|Crp/Fnr-family-transcriptional-regulator	unknown	unknown	gnl|CDD|223736
NC_008312.1|WP_081432397.1|1587406_1591381_-|5-oxoprolinase	unknown	unknown	gnl|CDD|215358
NC_008312.1|WP_011610783.1|1591705_1593103_-|NCS2-family-permease	unknown	unknown	gnl|CDD|225161
NC_008312.1|WP_081432398.1|1607633_1608221_-|hypothetical-protein	unknown	unknown	gnl|CDD|223704
NC_008312.1|WP_011610797.1|1627717_1628632_+|VWA-domain-containing-protein	unknown	unknown	gnl|CDD|214621
NC_008312.1|WP_011610791.1|1605056_1606238_-|protein-kinase	unknown	unknown	gnl|CDD|270916
NC_008312.1|WP_011610798.1|1629978_1630473_+|TerB-family-tellurite-resistance-protein	unknown	unknown	gnl|CDD|143581
NC_008312.1|WP_011610788.1|1602685_1603732_+|cobalamin-biosynthesis-protein-CobW	unknown	unknown	gnl|CDD|274151
NC_008312.1|WP_044136431.1|1608193_1608409_-|hypothetical-protein	unknown	unknown	gnl|CDD|223704
NC_008312.1|WP_155994309.1|1597721_1597895_+|hypothetical-protein	unknown	unknown	unknown
NC_008312.1|WP_011610794.1|1619339_1621193_-|SUMF1/EgtB/PvdO-family-nonheme-iron-enzyme	unknown	unknown	gnl|CDD|224182
NC_008312.1|WP_011610785.1|1594656_1595790_+|iron-containing-alcohol-dehydrogenase-family-protein	unknown	unknown	gnl|CDD|341480

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_008312.1|WP_011610781.1|1585963_1586881_+|homoserine-kinase	gnl|CDD|234920	PRK01212, PRK01212, homoserine kinase; Provisional.	2.25922e-132
NC_008312.1|WP_011610795.1|1624554_1625238_+|Crp/Fnr-family-transcriptional-regulator	gnl|CDD|223736	COG0664, Crp, cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms].	1.55352e-40
NC_008312.1|WP_155994311.1|1617907_1618084_+|hypothetical-protein	gnl|CDD|223704	COG0631, PTC1, Serine/threonine protein phosphatase [Signal transduction mechanisms].	0.000986502
NC_008312.1|WP_011610796.1|1625439_1627242_+|M61-family-metallopeptidase	gnl|CDD|226483	COG3975, COG3975, Predicted protease with the C-terminal PDZ domain [General function prediction only].	0
NC_008312.1|WP_011610787.1|1601166_1601847_+|HupE/UreJ-family-protein	gnl|CDD|368209	pfam04955, HupE_UreJ, HupE / UreJ protein. This family of proteins are hydrogenase / urease accessory proteins. The alignment contains many conserved histidines that are likely to be involved in nickel binding. The members usually have five membrane-spanning regions.	3.37174e-41
NC_008312.1|WP_044136428.1|1596120_1597305_+|aspartate-aminotransferase	gnl|CDD|180317	PRK05942, PRK05942, aspartate aminotransferase; Provisional.	0
NC_008312.1|WP_011610792.1|1615166_1615469_+|diversity-generating-retroelement-protein-Avd	gnl|CDD|380307	NF033474, DivGenRetAVD, diversity-generating retroelement protein Avd. Avd (accessory variability determinant) is part of diversity-generating retroelement (GDR) system through which a portion of a protein-coding gene can be rewritten, creating diversity that can affect host range. The founding member of this family, bAvd, from a Bordetella bacteriophage, belongs to a retrohoming element called BPP-1. Members of this family are four-helix bundle proteins, related to those of family TIGR02436, some of whose members are found in long intervening sequence (IVS) regions in 23S rRNA.	6.4872e-36
NC_008312.1|WP_081432397.1|1587406_1591381_-|5-oxoprolinase	gnl|CDD|215358	PLN02666, PLN02666, 5-oxoprolinase.	0
NC_008312.1|WP_011610783.1|1591705_1593103_-|NCS2-family-permease	gnl|CDD|225161	COG2252, COG2252, Xanthine/uracil/vitamin C permease [Nucleotide transport and metabolism].	3.74328e-151
NC_008312.1|WP_081432398.1|1607633_1608221_-|hypothetical-protein	gnl|CDD|223704	COG0631, PTC1, Serine/threonine protein phosphatase [Signal transduction mechanisms].	1.93029e-21
NC_008312.1|WP_011610797.1|1627717_1628632_+|VWA-domain-containing-protein	gnl|CDD|214621	smart00327, VWA, von Willebrand factor (vWF) type A domain. VWA domains in extracellular eukaryotic proteins mediate adhesion via metal ion-dependent adhesion sites (MIDAS). Intracellular VWA domains and homologues in prokaryotes have recently been identified. The proposed VWA domains in integrin beta subunits have recently been substantiated using sequence-based methods.	0.0048815
NC_008312.1|WP_011610791.1|1605056_1606238_-|protein-kinase	gnl|CDD|270916	cd14014, STKc_PknB_like, Catalytic domain of bacterial Serine/Threonine kinases, PknB and similar proteins. STKs catalyze the transfer of the gamma-phosphoryl group from ATP to serine/threonine residues on protein substrates. This subfamily includes many bacterial eukaryotic-type STKs including Staphylococcus aureus PknB (also called PrkC or Stk1), Bacillus subtilis PrkC, and Mycobacterium tuberculosis Pkn proteins (PknB, PknD, PknE, PknF, PknL, and PknH), among others. S. aureus PknB is the only eukaryotic-type STK present in this species, although many microorganisms encode for several such proteins. It is important for the survival and pathogenesis of S. aureus as it is involved in the regulation of purine and pyrimidine biosynthesis, cell wall metabolism, autolysis, virulence, and antibiotic resistance. M. tuberculosis PknB is essential for growth and it acts on diverse substrates including proteins involved in peptidoglycan synthesis, cell division, transcription, stress responses, and metabolic regulation. B. subtilis PrkC is located at the inner membrane of endospores and functions to trigger spore germination. Bacterial STKs in this subfamily show varied domain architectures. The well-characterized members such as S. aureus and M. tuberculosis PknB, and B. subtilis PrkC, contain an N-terminal cytosolic kinase domain, a transmembrane (TM) segment, and mutliple C-terminal extracellular PASTA domains. The PknB subfamily is part of a larger superfamily that includes the catalytic domains of other protein STKs, protein tyrosine kinases, RIO kinases, aminoglycoside phosphotransferase, choline kinase, and phosphoinositide 3-kinase.	1.87364e-72
NC_008312.1|WP_011610798.1|1629978_1630473_+|TerB-family-tellurite-resistance-protein	gnl|CDD|143581	cd07177, terB_like, tellurium resistance terB-like protein. This family consists of tellurium resistance terB proteins, N-terminal domain of heat shock DnaJ-like proteins, N-terminal domain of Mo-dependent nitrogenase-like proteins, C-terminal domain of ABC transporter ATP-binding proteins, C-terminal domain of serine/threonine protein kinase, and many hypothetical bacterial proteins. The function of this family is unknown.	7.90964e-07
NC_008312.1|WP_011610788.1|1602685_1603732_+|cobalamin-biosynthesis-protein-CobW	gnl|CDD|274151	TIGR02475, Probable_cobalamine_biosynthesis_protein, cobalamin biosynthesis protein CobW. The family of proteins identified by this model is generally found proximal to the trimeric cobaltochelatase subunit CobN which is essential for vitamin B12 (cobalamin) biosynthesis. The protein contains an P-loop nucleotide-binding loop in the N-terminal domain and a histidine-rich region in the C-terminal portion suggesting a role in metal binding, possibly as an intermediary between the cobalt transport and chelation systems. A broader CobW family is delineated by two Pfam models which identify the N- and C-terminal domains (pfam02492 and pfam07683). [Biosynthesis of cofactors, prosthetic groups, and carriers, Heme, porphyrin, and cobalamin].	2.83831e-167
NC_008312.1|WP_011610785.1|1594656_1595790_+|iron-containing-alcohol-dehydrogenase-family-protein	gnl|CDD|341480	cd08550, GlyDH-like, Glycerol_dehydrogenase-like. This family contains glycerol dehydrogenase (GlyDH)-like proteins. Glycerol dehydrogenases (GlyDH) is a key enzyme in the glycerol dissimilation pathway. In anaerobic conditions, many microorganisms utilize glycerol as a source of carbon through coupled oxidative and reductive pathways. One of the pathways involves the oxidation of glycerol to dihydroxyacetone with the reduction of NAD+ to NADH catalyzed by glycerol dehydrogenases. Dihydroxyacetone is then phosphorylated by dihydroxyacetone kinase and enters the glycolytic pathway for further degradation. The activity of GlyDH is zinc-dependent; the zinc ion plays a role in stabilizing an alkoxide intermediate at the active site. Some subfamilies have yet to be characterized.	1.57485e-140
NC_008312.1|WP_011610794.1|1619339_1621193_-|SUMF1/EgtB/PvdO-family-nonheme-iron-enzyme	gnl|CDD|224182	COG1262, COG1262, Uncharacterized conserved protein [Function unknown].	5.2535e-79
NC_008312.1|WP_044136431.1|1608193_1608409_-|hypothetical-protein	gnl|CDD|223704	COG0631, PTC1, Serine/threonine protein phosphatase [Signal transduction mechanisms].	1.2462e-05

Protein sequences

>NC_008312.1|WP_011610791.1|1605056_1606238_-|protein-kinase
MVGGKIPININKIGEIELLELLGTGTFGSAWKAIDHSHKKNYILKVIQGIKPEETLVERIRLEAAVNIPSENIIPLLGLKEWDANTYLILFEYFPGKRLDKLLEKKSLNNRQKKQIFKQILLGISAAHQCNIIHRDLKPANIIISNDMQTKIIDFGVAKFKDQNITMSKEIIDTPPYMAPEFLIEGAKVADAKSDIYSLGHILYELAMGENFWRHSGWYKLEDFIKYLTQTPTPKIGIDLNDFYCDFFPEVEQVLSQMMKINPEERYQSVEDVICDLEIPLEYPKLPIALNFEYPLLIVESGNNKGARTFVNINDSGSLILGRVDIAGADTTISRQHLEFMRKENNYFVRDLGSKNGTMLKGKMIDNYPVEIKHGNMIKVGDVFLRFVFLDRS
>NC_008312.1|WP_011610788.1|1602685_1603732_+|cobalamin-biosynthesis-protein-CobW
MSAKIPVTVITGFLGSGKTTTIRHLLKNNKGRRIAVLVNEFGEVGIDGDLLRSCQVYDEEGIINNIVELNNGCLCCTVQEEFFPTMQELLKRREKIDSILIETSGLALPKPLVQAFRWPQIKTSATVDGVVTVVDCEAVANGSLVGDIDALKAQRQADPNLDHETPIEELFEDQLACADLVLLTKVDMVDEATSDKVQNWLREHLPKTVKIVPCIGGEINPDLLLGFNAVVEDNLDSRPSHHDTQEEHEHDDEINSVHLILDEEFEPQGLVEKLNGLVTNSEIYRIKGFVAVPNKSMRLVLQGVGSRFDFFYDRLWQKQETRQTKLVLIGRSLQREKIYSELVSNFSN
>NC_008312.1|WP_011610787.1|1601166_1601847_+|HupE/UreJ-family-protein
MTYKHSKFTKIRMGNQLNKILTIVIVTCTSLIFFSTTELAMAHHPMGGKIPANFWEGLISGMGHPIIGIDHLSFVVGVGLIAAGMSNSILVLVSFLATAMLGTGIHLLSIDLPLTEIAIAISVVALGAMLAFKQKLNTPLVIIFAAISGIFHGYAYGEAIIGSEMTPLLAYLIGFTAMQLFIALFAMKSAELVSSYWQNQFFRLMSFLGLFISTIGLVFFTKAILN
>NC_008312.1|WP_155994309.1|1597721_1597895_+|hypothetical-protein
MVKFSEILGRYNQLQLGFDELKDRRHQHQGRETKLSEIDQPEHMASTIRATRRWKFI
>NC_008312.1|WP_044136428.1|1596120_1597305_+|aspartate-aminotransferase
MTMYSINPAKRVQALPPYVFARLDELKARAREQGLDLIDLGMGNPDGATPKPVVEAAIAALQDSTNHGYPPFEGTASFRKAITDWYFRRYSVKLDPDGEALPLLGSKEGLTHLALAYINPGNLVLAPNPAYPAHFRGPLIAGGKVHSILLKPENDWIIDLADIPDSVAEQAKVFYFNYPSNPTGATAPREFFQDIVTFAKKYEILLVHDLCYAELAFDGYQPTSLLQIPGGKDIGVEFHTMSKTYNMAGWRIGFVVGNSNVIQGLRTLKTNMDYGVFSALQLAAKTALQLPDEYLSQVQERYRQRRDFLIQGLGKLGWNVQKTMATMYLWVPCPPGIGSTDFALSVLQKTGVVVTPGNAFGSGGEGYVRISLIAECKRLDEALNRFKKAGIYYQ
>NC_008312.1|WP_011610785.1|1594656_1595790_+|iron-containing-alcohol-dehydrogenase-family-protein
MIKSTHISQTATTLLSLNIAPTQIIRGKNALAQSGEAIARIGHHPLIVGSPRSLNIILPHLQPLLQIHNLKFTQANYGSDCSETSLANLSQAVATQKPDLIIGIGGGKALDTAKLLAYKCHLPIITIPTSAATCAAWTALSNIYSDQGAFLYDISLAKCPELLILDYGIIKTGPSRTLVAGIGDAIAKWYEASVSSGHSESTMIISAVQQARVLRDILFQKSTFALEQPGGETWQEVVDATVLLAGLIGSIGGAQCRTVAAHAIHNGLTHLSASHEKLHGEKVAYGILVQLRLEEMLQSNQLAATARQQLLKFYNQIGLPKSLNDLGLKEITLSELRHVAEVACHPNSDIHRLPFRIIPEQLVAAMVSTTVPLELEK
>NC_008312.1|WP_011610784.1|1594182_1594482_-|hypothetical-protein
MKGSFAEYTQESSIQIKFYYIDGNTETFSFPANVEQFQTQLQDLLKQPWITFHLMDQTVCIYTEKIMKIEIKPPISQMEGEGVFANSERITALQINASR
>NC_008312.1|WP_011610783.1|1591705_1593103_-|NCS2-family-permease
MTKEIDKSKKVISTNESNSALDKNPIARFFRFRQLQTNFRTEIIAGITSFMTMSYILVVNPSILSNAIFLEKPGDLFGELVIATAISAVIATLIMGVYAKYPFALAPGMGLNAYFAFSVVLELGIDWRVALAAILLEGLIFIGLTVTNVRNKIITAIPDCIKHATSAGIGLFIAYIALKNAGLIAPSETTTTTLGDLTQPTTLVAITGILIAFALVVREIKGALFWGIIATSLLGWIFGLTPPPKGIMSIPQLPTDLFGQAFVGLTQIWQINIWEIFRIVLVFLFVDLFDTVGTLTGLGTKARYINKKGKFPGVNRALMADAIGTTAGAIMGTSTVTTYIESASGISEGGRSGFTAVVTALLFVVAIFFIPLLSAIPTFATAPALLIVSILMMSAVKNILWDDPGESIPSFLTIIMMPLSYSIAEGLAFGLITFPLLKTFQGKPQETTSVMWILALVFILRFLLN
>NC_008312.1|WP_081432397.1|1587406_1591381_-|5-oxoprolinase
MTNNRWKFWIDRGGTFTDIVAKSPEGKIIIHKLLSENPEHYPDAPVQGIREILKISQNQPIPLKEIEVIKMGTTVATNALLERKGDRTVLVINKGFKDALRIGYQNRPNIFARQIILPEMLYEKVIEVESRYTAKGEEIIPLQTTELISQLQTAYNEGIRSCAIVLIHGYRYPKHEQKIQEIAEKIGFTQVSVSHEVSPLMKLVSRGDTTVVDAYLSPILRRYVNQVRDFLLEKSGGNKKQGKDVLNSSNSPDINLVKLMFMQSNGGLTDAHKFQGKDSLLSGPAGGIVGAVQTSKNAGFYQIISFDMGGTSTDVAHYAGAANQIIEYEREFETEIAGIRLRTPMMSIHTVAAGGGSILFFDGARYRVGPESAGANPGPAAYGKGGPLTVTDCNLMVGKIQPEFFPKVFGKDRNLPLNLEIVQEKFAQLTAKIGDSRKPEEVASGYLAIAVEKMANAIKKISLQKGYDISEYTLCCFGGAGGQHACLIADSLGMKKIFIHPYAGVLSAYGMGLADIRVMKEKAVEKTLTPELLLELEQIFTTLEMETKQELITGSFSSQDSDLESIFCHSVLSKVRLKYQGSDSVLIVDFAKNIYTVKAEFETAHRQRYGFIMTEKSLIVEAVSLELIQHMETPEEIEKYPNQKSPTTPVTTTQIYTAEKWHDTPIYLRENLQPGDKINSPALIVEKTGTNVIEPGWQAELNAKNHLILTKSKTTEKSIYLTTKFQTKTSTSADPVMLEIFNNLFRAIAEQMGITLQNTSSSVNIKERLDFSCAIFDQDGELVANAPHIPIHLGSMSESVNALIYDKGNTFKPGDVYVLNNPYNGGTHLPDITVITPVFSTLEKPKNSSVIAKDNLENKSNNIFFETNYTEEIVSDTNITLNNNYITQKSKYINFPNNKKLISENEANISLTSLKNREKIRTPIFYVASRGHHADIGGITPGSMPPHSKTVEEEGILIDNFQLVKDGKFQETELLKILSSGKYPARNTKQNIADLQAQVAANEKGVQELQKMTAYYGLETVQAYMKFVQDNAESSVRKAIKKLSSSLTNKTATSILDDGNKISVAVSIDKKNLSAKIDFTGTSPQLSNNFNAPTAVCKAAVLYVFRTLVDDDIPLNAGCLKPLEIIIPQGSMLDPKYPAAVVAGNVETSQGIGDTLYNALGIMASSQGTMNNFTFGNSKYQYYETICGGSGAGTDFDGTDAVHTHMTNSRLTDPEVLEWRFPVLLESFAIRSGSGGKGLYKGGNGVVRRMRFLEPMTAGILSGHRAVSTLGLNGGGDGLVGKNYVERSNGKVEELGGTATVEMNIGDVFVIETPGGGGNSSFVK
>NC_008312.1|WP_011610781.1|1585963_1586881_+|homoserine-kinase
MTTLSSITVSVPATTANLGPGFDCLGAAISLYNRFKFSIADSAIEVKITVTGKEAPKVSTDRNNLAYQAFVKLYEYINQTPPCVLVEIDLGVPLARGLGSSATAIVGGLLGANQLAGSPLSQTEVMNLAIAIEGHPDNVVPALLGGCRLTASTSKGWVVCDIPWHPDIVPVVAIPDFELSTTEARRVIPTEYIRSDAIFNCAHLGILLRGLETGYGEWLQAGMQDKIHQPYRKSLIKGYEYVRSAALNAGAYEMVISGAGPTLLALTNSLTSSKVIAAMTGAWENQGVVTQVQALEINTRGAVFS
>NC_008312.1|WP_081432398.1|1607633_1608221_-|hypothetical-protein
MSLSLFETLVFEPSINNQEKSKKLPTIETLTIAIKEAIAETNAHIKRIIKNNSWDKSGATLAVALISEAIAIISNLGDSLIYHYSHQNYGQKIRQITDNHTLASAIRRGGIIISEMAAHHEGKNMLEFYLGCDNLPPDLPIHYVSLYAEDLLLLCSDGVSSNFQEKELKDILSEGDLKKISKKLISQSQQGGGNG
>NC_008312.1|WP_044136431.1|1608193_1608409_-|hypothetical-protein
MKTTNIEYVSRSETNKRPKNEDSFIICQLTPNPKQSPLTLLAISDGIGGYEHGEEISREVLKRSASAYLKP
>NC_008312.1|WP_011610792.1|1615166_1615469_+|diversity-generating-retroelement-protein-Avd
MNELSIIQKTYDLIIWYVPIINRLPKTHKFQIGDRLVNNLYNFLELLIIAKYASEKLNILESLNPKLDIVRYQNRIILDFQIINNKRYEYISQIITEIGK
>NC_008312.1|WP_155994310.1|1616567_1616738_-|hypothetical-protein
MKARNHRGRRDDSKTPIVVEVVGIFIVAPGTPAMSRIVVPATATELWFVSPVIILP
>NC_008312.1|WP_155994311.1|1617907_1618084_+|hypothetical-protein
MKTTNIEYVSRSETNKRPKNEDSFIICQLTPNPKQSPLTLLAISDGIGGKEKNSRFKI
>NC_008312.1|WP_011610794.1|1619339_1621193_-|SUMF1/EgtB/PvdO-family-nonheme-iron-enzyme
MRCLNCHTDGIPLETKICYNCGAYLPSLIRGLLTPGTQLGDKPYQIDYPLGRGGFGVTYRGHHTLLKQIVAIKEYYPQNYALRHPTTGGFTIPRNQQEIFQQGLRRFLQEGKILAQLNHPHVVRVIDLFEENETAYLVMELVRGKSLRKELDSQPEKKFPPQKVKEIITDLVSALSAVHQQGIFHLDIKPDNILLTPEGRLVLTDFGSAKQTFGTSMGTSSTESFAESYAAPEVLARGEVGVESDIFEVGMMVYEMLSGQLPPNVLERSLSKEKSWEPEGLESSWQKLLMSALVLAKEGRPGNIEEWWEMNFHKKSTERTQESGWKTKEFKNRKKDISSPPRQKFGFEVIKVNSRGKEIDRRSYEAEFLAENLDSGLVLEMVYIPGGSFLMGSPEYEDERFDSESPQHQVNIKPFLMSKYPITQDQYQAIMGDNPSYFKGGKRPVERVSWHDATKFCEKLSSKTGKIYRLPSESQWEYACRAGTSTPFYFGETMTSELVNYDGNYPYGNAPFGEYREQTTDVGSFLPNAFGLYDMHGNVSEWCLDAWHHNYYGAPTNGSAWKTGGSNRKRVLRGGCWDSYSTNCRSAWRFYYNADDLYYYRGFRVVSSSPVVSAFNS
>NC_008312.1|WP_011610795.1|1624554_1625238_+|Crp/Fnr-family-transcriptional-regulator
MQTEAFSELFPLFKGANPETLEWLLSVAVKHEYPSNRLVLMEDAWGNAVYFVVSGWVKVRRRLSPDNSVTLAILGRGDFFGEMAILDESPRSNDVVALSPVRLISISAQRFIQTLFKDPQLHHRMLQLMVKRLRQTNVRYQLRNRPPAVKLANTLVELAENYGQTTEKTCEIFNIPDQDLGDVTDITIDETTKIMAKLHNKGWIKRDPEHQLMHLLNLKHLMHLASQ
>NC_008312.1|WP_011610796.1|1625439_1627242_+|M61-family-metallopeptidase
MTEAKILTISPTITSPAIQYKVSMPHPESHLFEVSLSVRVEELSSSLLQMSKKLDLKMPVWTPGSYLIREYAKHLQDFCAYSENKQPLPWQKLSKNHWQIETLGVSKVIVQYKIFANELTVRTNHLDSTHAYFNGAALFFYIPECEKNKIRLEVISPLPNWQITTSLPKTPNTENTFEAEDFDTLVDSPFEIGNHQLYQFEVEGKKHQLAIWGKGNAEPEKLIPDIQKIIAVEAEFFGGLPYEEYLFILHSSSKGFGGLEHKFSCTLNYPRFGFRNKEKRDRFMQLVAHEFFHLWNVKRIRPKALEEFDYDQENYTPSLWFSEGTTSYYDLLIPLRAGIYDVQTFLKELGKEITLLLTTIGRKVQPVSESSWDAWIKLYRRDNNSNNCQISYYLKGAMISLLLDLLIREKYENQRSLDDVMYQMWEKFGKSEIGFTPEQLKAVIEEVAELDLGNFFKRYIDGLDELPFDEYFGHFGLQLKKEDNEWPDWGMNVVSENNKEIIKFVENNGPAQLAGINAGDQLLAINGFRVNADKLGYRLKDYQPGDILEVTVFHQDELITHQITLAHPGPSRYQLVPVKNPTATQEKNFVGWLGSSLESI
>NC_008312.1|WP_011610797.1|1627717_1628632_+|VWA-domain-containing-protein
MNIKDKYLQASTLFLTLVTVGATSATAASLKSSDVVVIVDEYGSMNYEQTWLGTVIPQLDTALQNQGIVGNRFGLVGFGTSNQTLGRSLPLGGAKFGNSAEFATATNSLLLKGGFEDGYSAIDFALNNYTFREGAAVNFILVTDEDRDNGNSSLNFNNILARLKRNPQDNKDDILLNAIVNANFVNNSLGVNSEGNAYIANGSGGYTTTQLPQPLTNFITSDFGTTKLDYIDLALDSGGTGWDLNQLRDGGLTGTSFAKAFIDIKVEEIKNQQIPEPGLVLGLLSAGVLGVISLGKKLTQSVLN
>NC_008312.1|WP_011610798.1|1629978_1630473_+|TerB-family-tellurite-resistance-protein
MTVQPPPPPSITPRQMDLLRIVAYMAWSDGQLAQEEVELMLNRFSSLFATGDSQQQLQEELRDYLMQNIPLEESIPKLESQQERELVLKLGYEVIACSARTPEEANINEEEEVAYQKLKQLLNISKDVVKRIEAEANTELNQQKQQGIVEMMTHGLEQHLHKQN

Crispr_ID: NC_008312_13

• CRISPR_ID: NC_008312_13
• CRISPR_location: 1645960-1646085
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NC_008312_13

Consensus_repeat	Method
CAAATTTACCTAACATTAGAAAACCAAAAATTATGT	CRISPRCasFinder

spacers of NC_008312_13

>13.1|1645996|54|NC_008312|CRISPRCasFinder
GTTGAATAGTAGAAAAACTAGATAGGTTATTACCAATAGTTAGTTTATACAGAC

CRISPR arrays and Neighbor proteins around NC_008312_13

CRISPR arrays

The CRISPR arrays of NC_008312_13

>merge|NC_008312|13|1645960-1646085|CRISPRCasFinder
CAAATTTACCTAACATTAGAAAACCAAAAATTATGTGTTGAATAGTAGAAAAACTAGATAGGTTATTACCAATAGTTAGTTTATACAGACCAAATTTACCTAACATTAGAAAAGCAAAAATTATGT

>NC_008312|13|10|1645960-1646085|CRISPRCasFinder
CAAATTTACCTAACATTAGAAAACCAAAAATTATGT	GTTGAATAGTAGAAAAACTAGATAGGTTATTACCAATAGTTAGTTTATACAGAC
CAAATTTACCTAACATTAGAAAAGCAAAAATTATGT

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_008312.1|WP_155994313.1|1651768_1651912_-|hypothetical-protein	unknown	unknown	unknown
NC_008312.1|WP_011610811.1|1648440_1649709_+|S-layer-homology-domain-containing-protein	unknown	unknown	gnl|CDD|306825
NC_008312.1|WP_011610815.1|1654058_1655711_-|SulP-family-inorganic-anion-transporter	unknown	unknown	gnl|CDD|223732
NC_008312.1|WP_011610797.1|1627717_1628632_+|VWA-domain-containing-protein	unknown	unknown	gnl|CDD|214621
NC_008312.1|WP_011610801.1|1633211_1634891_+|AarF/ABC1/UbiB-kinase-family-protein	unknown	unknown	gnl|CDD|223733
NC_008312.1|WP_052845749.1|1656677_1656884_-|hypothetical-protein	unknown	unknown	gnl|CDD|290455
NC_008312.1|WP_011610796.1|1625439_1627242_+|M61-family-metallopeptidase	unknown	unknown	gnl|CDD|226483
NC_008312.1|WP_011610798.1|1629978_1630473_+|TerB-family-tellurite-resistance-protein	unknown	unknown	gnl|CDD|143581
NC_008312.1|WP_044136434.1|1650964_1651159_+|hypothetical-protein	unknown	unknown	unknown
NC_008312.1|WP_011610800.1|1632116_1632995_+|hypothetical-protein	unknown	unknown	unknown
NC_008312.1|WP_011610804.1|1636297_1636651_-|DUF1257-domain-containing-protein	unknown	unknown	gnl|CDD|377725
NC_008312.1|WP_011610814.1|1652248_1653973_+|SulP-family-inorganic-anion-transporter	unknown	unknown	gnl|CDD|223732
NC_008312.1|WP_081432399.1|1643889_1644147_-|hypothetical-protein	unknown	unknown	gnl|CDD|315923
NC_008312.1|WP_011610817.1|1661571_1662207_-|tRNA-(adenosine(37)-N6)-threonylcarbamoyltransferase-complex-dimerization-subunit-type-1-TsaB	unknown	unknown	gnl|CDD|274750
NC_008312.1|WP_011610810.1|1647639_1648356_-|glycerophosphodiester-phosphodiesterase	unknown	unknown	gnl|CDD|176499
NC_008312.1|WP_011610799.1|1631176_1631728_-|3-isopropylmalate-dehydratase-small-subunit	unknown	unknown	gnl|CDD|177701
NC_008312.1|WP_011610806.1|1638480_1638831_-|hypothetical-protein	unknown	unknown	unknown
NC_008312.1|WP_011610816.1|1655921_1656212_+|helix-turn-helix-domain-containing-protein	unknown	unknown	gnl|CDD|379154
NC_008312.1|WP_011610805.1|1636807_1638328_-|AAA-family-ATPase	unknown	unknown	gnl|CDD|177094
NC_008312.1|WP_155994312.1|1650526_1650694_-|hypothetical-protein	unknown	unknown	unknown

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_008312.1|WP_011610811.1|1648440_1649709_+|S-layer-homology-domain-containing-protein	gnl|CDD|306825	pfam00395, SLH, S-layer homology domain.	1.29357e-07
NC_008312.1|WP_011610797.1|1627717_1628632_+|VWA-domain-containing-protein	gnl|CDD|214621	smart00327, VWA, von Willebrand factor (vWF) type A domain. VWA domains in extracellular eukaryotic proteins mediate adhesion via metal ion-dependent adhesion sites (MIDAS). Intracellular VWA domains and homologues in prokaryotes have recently been identified. The proposed VWA domains in integrin beta subunits have recently been substantiated using sequence-based methods.	0.0048815
NC_008312.1|WP_011610801.1|1633211_1634891_+|AarF/ABC1/UbiB-kinase-family-protein	gnl|CDD|223733	COG0661, AarF, Predicted unusual protein kinase [General function prediction only].	8.9387e-150
NC_008312.1|WP_052845749.1|1656677_1656884_-|hypothetical-protein	gnl|CDD|290455	pfam13737, DDE_Tnp_1_5, Transposase DDE domain. Transposase proteins are necessary for efficient DNA transposition. This domain is a member of the DDE superfamily, which contain three carboxylate residues that are believed to be responsible for coordinating metal ions needed for catalysis.	3.35141e-08
NC_008312.1|WP_011610798.1|1629978_1630473_+|TerB-family-tellurite-resistance-protein	gnl|CDD|143581	cd07177, terB_like, tellurium resistance terB-like protein. This family consists of tellurium resistance terB proteins, N-terminal domain of heat shock DnaJ-like proteins, N-terminal domain of Mo-dependent nitrogenase-like proteins, C-terminal domain of ABC transporter ATP-binding proteins, C-terminal domain of serine/threonine protein kinase, and many hypothetical bacterial proteins. The function of this family is unknown.	7.90964e-07
NC_008312.1|WP_011610796.1|1625439_1627242_+|M61-family-metallopeptidase	gnl|CDD|226483	COG3975, COG3975, Predicted protease with the C-terminal PDZ domain [General function prediction only].	0
NC_008312.1|WP_011610804.1|1636297_1636651_-|DUF1257-domain-containing-protein	gnl|CDD|377725	pfam06868, DUF1257, Protein of unknown function (DUF1257). This family contains hypothetical proteins of unknown function that are approximately 120 residues long. Family members include eukaryotic and bacterial proteins.	1.19293e-27
NC_008312.1|WP_011610814.1|1652248_1653973_+|SulP-family-inorganic-anion-transporter	gnl|CDD|223732	COG0659, SUL1, Sulfate permease and related transporters (MFS superfamily) [Inorganic ion transport and metabolism].	5.40434e-147
NC_008312.1|WP_081432399.1|1643889_1644147_-|hypothetical-protein	gnl|CDD|315923	pfam13358, DDE_3, DDE superfamily endonuclease. This family of proteins are related to pfam00665 and are probably endonucleases of the DDE superfamily. Transposase proteins are necessary for efficient DNA transposition. This domain is a member of the DDE superfamily, which contain three carboxylate residues that are believed to be responsible for coordinating metal ions needed for catalysis. The catalytic activity of this enzyme involves DNA cleavage at a specific site followed by a strand transfer reaction.	2.74468e-06
NC_008312.1|WP_011610817.1|1661571_1662207_-|tRNA-(adenosine(37)-N6)-threonylcarbamoyltransferase-complex-dimerization-subunit-type-1-TsaB	gnl|CDD|274750	TIGR03725, T6A_YeaZ, tRNA threonylcarbamoyl adenosine modification protein YeaZ. This family describes a protein family, YeaZ, now associated with the threonylcarbamoyl adenosine (t6A) tRNA modification. Members of this family may occur as fusions with ygjD (previously gcp) or the ribosomal protein N-acetyltransferase rimI, and is frequently encoded next to rimI. [Protein synthesis, tRNA and rRNA base modification].	3.37724e-43
NC_008312.1|WP_011610810.1|1647639_1648356_-|glycerophosphodiester-phosphodiesterase	gnl|CDD|176499	cd08556, GDPD, Glycerophosphodiester phosphodiesterase domain as found in prokaryota and eukaryota, and similar proteins. The typical glycerophosphodiester phosphodiesterase domain (GDPD) consists of a TIM barrel and a small insertion domain named the GDPD-insertion (GDPD-I) domain, which is specific for GDPD proteins. This family corresponds to both typical GDPD domain and GDPD-like domain which lacks the GDPD-I region. Members in this family mainly consist of a large family of prokaryotic and eukaryotic glycerophosphodiester phosphodiesterases (GP-GDEs, EC 3.1.4.46), and a number of uncharacterized homologs. Sphingomyelinases D (SMases D) (sphingomyelin phosphodiesterase D, EC 3.1.4.41) from spider venom, SMases D-like proteins, and phospholipase D (PLD) from several pathogenic bacteria are also included in this family. GDPD plays an essential role in glycerol metabolism and catalyzes the hydrolysis of glycerophosphodiesters to sn-glycerol-3-phosphate (G3P) and the corresponding alcohols are major sources of carbon and phosphate. Its catalytic mechanism is based on the metal ion-dependent acid-base reaction, which is similar to that of phosphoinositide-specific phospholipases C (PI-PLCs, EC 3.1.4.11). Both, GDPD related proteins and PI-PLCs, belong to the superfamily of PI-PLC-like phosphodiesterases.	6.50192e-53
NC_008312.1|WP_011610799.1|1631176_1631728_-|3-isopropylmalate-dehydratase-small-subunit	gnl|CDD|177701	PLN00072, PLN00072, 3-isopropylmalate isomerase/dehydratase small subunit; Provisional.	1.55048e-104
NC_008312.1|WP_011610816.1|1655921_1656212_+|helix-turn-helix-domain-containing-protein	gnl|CDD|379154	pfam13384, HTH_23, Homeodomain-like domain.	7.2904e-07
NC_008312.1|WP_011610805.1|1636807_1638328_-|AAA-family-ATPase	gnl|CDD|177094	CHL00195, ycf46, Ycf46; Provisional.	7.58442e-167
NC_008312.1|WP_011610815.1|1654058_1655711_-|SulP-family-inorganic-anion-transporter	gnl|CDD|223732	COG0659, SUL1, Sulfate permease and related transporters (MFS superfamily) [Inorganic ion transport and metabolism].	7.60664e-141

Protein sequences

>NC_008312.1|WP_081432399.1|1643889_1644147_-|hypothetical-protein
MNYPQAGKIKLVCDHLNTHNIASLYEAFPAPEAHHLARRLEIYHTPGNSIWLNVAEIELIILSKQCLDRHIPTTEELHKELEACN
>NC_008312.1|WP_011610806.1|1638480_1638831_-|hypothetical-protein
MQDKQKVTLYIQPELHRKLKIRAAVDSEPMSSIAERAILFYLENPEVIDDSSSRYGQTHRVYSCPECTSSLIVREGELVSIKNQPNVLVDENIPVKQAPEIEKSEVQPGEQELVPC
>NC_008312.1|WP_011610805.1|1636807_1638328_-|AAA-family-ATPase
MKEELNILIEAQYPLIYLVTSEEERSEQAILALAQRKLQRKVFVWTVTHGITDYDQSKNTTQHNTVSPESAIEWVIRQRDPNTGAGIYVFKDLHPFIDSPPVTRWLRDAIASFKGTKKTIILMSPVQNVPIELEKEVVVLDFPLPDMKELNQVLSGQLDSAKNRRISTETREKLLKAALGLTKDEAEKVYRKAQVTAGRLTEKEVDIVLSEKKQLIRRNGILEYIEKDETINAVGGLEELKHWLRQRSDAFTERAREYGLPQPKGMLILGIPGCGKSLIAKTTSGLWGLPLLRLDMGRVYDGSMVGRSEANLRNALRTAESISPAILFIDELDKAFAGSTGSADSDGGTSSRIFGSFLTWMQEKTSPVFVMATANRVERLPGEFLRKGRFDEIFFVDLPNKEERQDIFQIHLIKRRRDIERFDLDQLSNVSDGFSGAEIEQAIIAAMYEAFAQDREFTQLDIIAAIKSTLPLSKTMTEQVTALRDWARQRARPAASSVAEYQRLEF
>NC_008312.1|WP_011610804.1|1636297_1636651_-|DUF1257-domain-containing-protein
MSHFSTLRTKITDAEILKASLGDLGVTVKTNADVRGYNGQRVRSDIVAVLEGEYDLGWSRNSDGSFDLIADLWGVAKKHNQTELINSINQKYAVNKTLATVKQRGLQNANVKLVVQK
>NC_008312.1|WP_011610801.1|1633211_1634891_+|AarF/ABC1/UbiB-kinase-family-protein
MLTKNSSKSRPWQRAQYSPLTRQIDVFSAAGKFFFFLWWDNLFQNKSSTLRRRRAEWLVKTMINLGPTFIKIGQSLSTRADILPKEYVEELGKLQDQVPPFETTEAIAIIESELGNSLYSLYRDFKEFPIAAASLGQVHKANLQTGEEVVVKIQRPGLKVLFDLDVKALKNVIRFCKRYFAWAKKYDLDVIYYDFFTILYQEIDYVNEGKNADRFRDNFQGYPDIVVPRVYWTHTTEKVITLEYLPGIKINDRREMEAYNLNPKLINQIGVCCYLKQLLLDGFFQADPHPGNLAVSSDGKVIFYDFGMMAEVKSLTKDQMIKTFFAVLKKDVEQVLNALITIGLIVPMSNMMPVRRLLDFLLENFTDKPVNFYDFDQIKEELYVLFEEQPFRLPSQMTFILKSLTTLDGIARELDPDYSLVSCSQPFVKSITFSKGKGRVVGELAKQTTDFIKYKLRQPSKSEVLIRQFQTKIEDGEIQFRVRSIEHDRLLKRINLALKVLIFTGFTGFTFLSGSVLLTGGYIKAAIIIFVLSVLGFIFLLKLGFQLSIKEKLDKIAEK
>NC_008312.1|WP_011610800.1|1632116_1632995_+|hypothetical-protein
MTNQINDTFMQARQGNIAAIIQVMNENLAKLGVRIRAIFSDGVLQVLCEAPEPQHLEKSSILKEVKQTLEEISPRNIQQIEINSRIFKYPQLLWLEDITKNPDNKLLWSQKIILTKPNIFKQIANNFYINKLKRTKIPMSKGILLKRMQRLDQFQPDIIGIFLLSLIMLTLGIQVNRWLNNSWIDQITTSENIASQPSFLNDKKSSEDTELKSKVAFTQAVRLAQKAVAYGKIAKSKEEWMAIAKIWEEAAELMASVSPSYSRHDVALDRAEIYQKNSDIAKTQVEKIVRGE
>NC_008312.1|WP_011610799.1|1631176_1631728_-|3-isopropylmalate-dehydratase-small-subunit
MTKSLTGKIFVLDDNIDTDQIIPAEYLTLVPSKPDEYDKLGTYALCGLPDRYGRFMEPEAMKTKYPIIVAGENFGCGSSREHAPIALGASGVQAVVAQSYARIFFRNCSATGELYPWESSDRLCELFKTGQKVTIDFEKNQIVNHTLDQTYQLKSLGEVRPVIDAGGLFAYARQTGMISQKEV
>NC_008312.1|WP_011610798.1|1629978_1630473_+|TerB-family-tellurite-resistance-protein
MTVQPPPPPSITPRQMDLLRIVAYMAWSDGQLAQEEVELMLNRFSSLFATGDSQQQLQEELRDYLMQNIPLEESIPKLESQQERELVLKLGYEVIACSARTPEEANINEEEEVAYQKLKQLLNISKDVVKRIEAEANTELNQQKQQGIVEMMTHGLEQHLHKQN
>NC_008312.1|WP_011610797.1|1627717_1628632_+|VWA-domain-containing-protein
MNIKDKYLQASTLFLTLVTVGATSATAASLKSSDVVVIVDEYGSMNYEQTWLGTVIPQLDTALQNQGIVGNRFGLVGFGTSNQTLGRSLPLGGAKFGNSAEFATATNSLLLKGGFEDGYSAIDFALNNYTFREGAAVNFILVTDEDRDNGNSSLNFNNILARLKRNPQDNKDDILLNAIVNANFVNNSLGVNSEGNAYIANGSGGYTTTQLPQPLTNFITSDFGTTKLDYIDLALDSGGTGWDLNQLRDGGLTGTSFAKAFIDIKVEEIKNQQIPEPGLVLGLLSAGVLGVISLGKKLTQSVLN
>NC_008312.1|WP_011610796.1|1625439_1627242_+|M61-family-metallopeptidase
MTEAKILTISPTITSPAIQYKVSMPHPESHLFEVSLSVRVEELSSSLLQMSKKLDLKMPVWTPGSYLIREYAKHLQDFCAYSENKQPLPWQKLSKNHWQIETLGVSKVIVQYKIFANELTVRTNHLDSTHAYFNGAALFFYIPECEKNKIRLEVISPLPNWQITTSLPKTPNTENTFEAEDFDTLVDSPFEIGNHQLYQFEVEGKKHQLAIWGKGNAEPEKLIPDIQKIIAVEAEFFGGLPYEEYLFILHSSSKGFGGLEHKFSCTLNYPRFGFRNKEKRDRFMQLVAHEFFHLWNVKRIRPKALEEFDYDQENYTPSLWFSEGTTSYYDLLIPLRAGIYDVQTFLKELGKEITLLLTTIGRKVQPVSESSWDAWIKLYRRDNNSNNCQISYYLKGAMISLLLDLLIREKYENQRSLDDVMYQMWEKFGKSEIGFTPEQLKAVIEEVAELDLGNFFKRYIDGLDELPFDEYFGHFGLQLKKEDNEWPDWGMNVVSENNKEIIKFVENNGPAQLAGINAGDQLLAINGFRVNADKLGYRLKDYQPGDILEVTVFHQDELITHQITLAHPGPSRYQLVPVKNPTATQEKNFVGWLGSSLESI
>NC_008312.1|WP_011610810.1|1647639_1648356_-|glycerophosphodiester-phosphodiesterase
MTTKPLIIAHRGASGLVKFENTLASFAKAIELGVSMVEFDVRKTQDNLLVAFHDESIDGIKLRDLTYQQLLNISQKKGFDVPLVEDVLKLCQRKIKLDIELKEAGYELEIVNLVKKYLDYQDYVIKSFIDTAIITLKKTDNKITTGLLLGLGNPQNFILTRLSEIFPEFRLLLTKADFVSPNYQLIKLGFVWRMKILNKNIYVWTINDEKLMSKIIKKGIFALITDRPDLALKLFDSN
>NC_008312.1|WP_011610811.1|1648440_1649709_+|S-layer-homology-domain-containing-protein
MTDTPTKLPSQLRPVKPDEWIAIFVALGTFGSIFFWATTGEKNGFNLLSKPMLSTPLSESFGSSNIASGKSIFSLDIPQLKTSTGKSGSNFEESSQNPEELGTSLDTLTSMTDPVEDDEPNLQSLDQVKTETKTIPKLFEVLKKINQKAAPPVADNLGILDSGKILSKSPPTISSEVTDDLITTAPLPVAPSIPTPTTELPQEKETSLPSTALPSPDISSSSTVKFSDVPNSFWASSFIQSLVEQDFIAQINNDQFEPDKPVTRAEFAAQIAKVFEEKSAKKSVVYKDIKGDSTAQSEIQTSTKSGFLSGYPGDVFRPEEKVSRLQVLVSLASGLSLEIPSDPDSVLSVYKDTTEIPDWAKEKVAAATAAELVVSHPDVKMLNPNQPATRAEVAAVFYQALVKLGQVEKISSEYIVNPKKEN
>NC_008312.1|WP_155994312.1|1650526_1650694_-|hypothetical-protein
MSLVATTRKLGLSFFEDVHDRISQTIEYSCCGNYYLCSRRVALAVSLPLDKTSNS
>NC_008312.1|WP_044136434.1|1650964_1651159_+|hypothetical-protein
MNYLQKWVLSNYRTQWQLGKHTYNILLLGIADHGLAIIIIWEILPKKGNSQTTERIGEICFPIR
>NC_008312.1|WP_155994313.1|1651768_1651912_-|hypothetical-protein
MYLISVGRELLATCQEIFEQLDRFEIIVADINSTRQGPKYRTKILTS
>NC_008312.1|WP_011610814.1|1652248_1653973_+|SulP-family-inorganic-anion-transporter
MATQVFNKIHFRNLQGDIFGGLTAAVIALPMALAFGVASGAGPAAGLYGSVLVGLFAALFGGTPTLISEPTGPMTVVMTAVIANLTATNPENGMTMAFTVVMLAGLFQISFGFLKLGKYITMMPYNVISGFMSGIGLILIILQIGPFLGQASPKGGVIATIENLPQLLNNINPIETGLAVLTVVILFSMPTKLKKIFPAPLVALVIGTIISIVFFSDIDIRRIGEIPSGLPSLQLPYFTAGQLQLMVVDAIVLAMLGCIDALLTSVVADSLTRTQHDSDKELIGQGLGNLASGLFGGIPGAGATMGTVVNINTGARTALSSITRAVILMVVVLGAASLTAQIPMAVLAGIAFQVGIKIIDWGFLKRAHRISWKSAIIMYAVIGLTVFVDLITAVGIGVFIANVLTIDRLTQLKSEDVKAITDADDAIILDNDEKELLDRAEGRILLFHLSGPMIFGISKAISRQHTHLNNYEVLIVDLSEVPHMGVTSALAIENVIQETIDTGRNVFLVGAAGSVKLRLEKLGVLNIVPSENMLMDRKQALVKAVALVTSDVNINDPIQNGAKGIQSGIDNIIK
>NC_008312.1|WP_011610815.1|1654058_1655711_-|SulP-family-inorganic-anion-transporter
MQLVNSLHFNNLRGDLLGGLTAAIVALPLALAFGVSSGAGAITGLYGAIFVGFFAALCGGTPSQITGPTGPMTVLMATVFTTLLADNPDAGLEMAFTVVMLGGIFQILFGVLQLGKYIVLIPYAVISGFMSGVGVIIIIIQIGPFLGHPASASVAQSIKKIPEFLINLNPAAVGLGILTIVILLFTPRKVTAIIPSPLLALLTGTLISVFFLSDSNLILIGEIPTGLPKLHLPVFTFNQLQNMLVDGLVLGTLGSIDSLLTSLVADNITRSNHDSDHELIGQGIGNIMSGLFGGLPGAGATMRTVVNVHAGGKTPLSGIVHSIILLLILLWAGKLTEAIPQAILAGILLKVGVDIIDWGFLKRAHNLSLKAAGIMYSVLILTVFVNLVTAVAVGIFIANLLTVKRLSDMQINDIKAIVEPNDEIPLRDQEKQLLKECRGHLLLLHLGGPMSFGAAKALSRHMGMVQQYDVLILDLSDVSYLGITMSLALENMVTEASRKHREVFIVGASGGVKTRLGKLKIWNFVPRQNLVGTRIKALQQTLNLLVERKI
>NC_008312.1|WP_011610816.1|1655921_1656212_+|helix-turn-helix-domain-containing-protein
MYYRCQQEYLRKRLLAIKYLYERKTRTEVSDLLNCHSQTLSTWIDKFLEGGLKNLLELMTHQVSSRLNIEQKQELKIMILEELPRDYVVDRNKWSW
>NC_008312.1|WP_052845749.1|1656677_1656884_-|hypothetical-protein
MELDLSIQNYTTVSRRIKKNGHTNVSSTIGSKAIHLLVDSTVVKVYGGGKWKIRQHGLGKGKLYLGVN
>NC_008312.1|WP_011610817.1|1661571_1662207_-|tRNA-(adenosine(37)-N6)-threonylcarbamoyltransferase-complex-dimerization-subunit-type-1-TsaB
MTNTEKKYGLAIHTTSPELGLAISNFDEYTRSQTWNLGRDLSNNLHQKLQEFILPQIWQDLSFITVAKGPGSFTGTRIGVVTARTLAQQLNIPLFAISTLATIAWSYKQKSHNLFLQMHAQRGQLFTAIYQVEEMGINPISGDTLMNPLVWEKMLVDWDNSYHLIQVKNSLGKYVVSLLELAHLEWQKGNRPHWSEALPFYGQSPVEKYPL

Crispr_ID: NC_008312_14

• CRISPR_ID: NC_008312_14
• CRISPR_location: 1851510-1851619
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 2 spacers

Consensus repeat of NC_008312_14

Consensus_repeat	Method
GTTCTGGTGTTGGTTCTGGTGTTGGT	CRISPRCasFinder

spacers of NC_008312_14

>14.1|1851536|16|NC_008312|CRISPRCasFinder
TCTGGTGTTGGTTCTG
>14.2|1851578|16|NC_008312|CRISPRCasFinder
GTTGTTTCTGGTGTTG

CRISPR arrays and Neighbor proteins around NC_008312_14

CRISPR arrays

The CRISPR arrays of NC_008312_14

>merge|NC_008312|14|1851510-1851619|CRISPRCasFinder
GAATTCTTGTTGGTTCTGGTGTTGGTTCTGGTGTTGGTTCTGGTGTTGGTTCTGGTGTTGGTTCTGGTGTTGTTTCTGGTGTTGGTTCTGGTGTTGGTTCTGGCGTTCGT

>NC_008312|14|11|1851510-1851619|CRISPRCasFinder
GAATTCTTGTTGGTTCTGGTGTTGGT	TCTGGTGTTGGTTCTG
GTGTTGGTTCTGGTGTTGGTTCTGGT	GTTGTTTCTGGTGTTG
GTTCTGGTGTTGGTTCTGGCGTTCGT

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_008312.1|WP_011610938.1|1869678_1870758_+|PIN/TRAM-domain-containing-protein	unknown	unknown	gnl|CDD|227292
NC_008312.1|WP_011610927.1|1853301_1854318_-|hypothetical-protein	unknown	unknown	gnl|CDD|224117
NC_008312.1|WP_044137207.1|1866981_1867239_-|DUF1830-domain-containing-protein	unknown	unknown	gnl|CDD|370162
NC_008312.1|WP_011610920.1|1837407_1838166_+|uroporphyrinogen-III-C-methyltransferase	unknown	unknown	gnl|CDD|235711
NC_008312.1|WP_071820548.1|1843886_1844102_+|IS1-family-transposase	unknown	unknown	gnl|CDD|224576
NC_008312.1|WP_155994324.1|1835656_1835818_+|hypothetical-protein	unknown	unknown	unknown
NC_008312.1|WP_011610919.1|1833836_1834673_+|diaminopimelate-epimerase	unknown	unknown	gnl|CDD|178151
NC_008312.1|WP_011610924.1|1849483_1850875_-|hypothetical-protein	unknown	unknown	unknown
NC_008312.1|WP_011610918.1|1833561_1833774_-|hypothetical-protein	unknown	unknown	gnl|CDD|212463
NC_008312.1|WP_155994323.1|1834963_1835116_+|hypothetical-protein	unknown	unknown	unknown
NC_008312.1|WP_044136459.1|1867439_1868708_-|coproporphyrinogen-III-oxidase	unknown	unknown	gnl|CDD|236007
NC_008312.1|WP_011610930.1|1857686_1858649_-|hypothetical-protein	unknown	unknown	gnl|CDD|224117
NC_008312.1|WP_011610939.1|1871193_1871847_+|glycosyltransferase	unknown	unknown	gnl|CDD|275102
NC_008312.1|WP_011610933.1|1862475_1863948_-|hypothetical-protein	unknown	unknown	gnl|CDD|372732
NC_008312.1|WP_081432405.1|1840226_1840397_-|hypothetical-protein	unknown	unknown	gnl|CDD|315923
NC_008312.1|WP_011610928.1|1854402_1855686_-|hypothetical-protein	unknown	unknown	unknown
NC_008312.1|WP_011610921.1|1838474_1839092_+|molybdenum-cofactor-guanylyltransferase	unknown	unknown	gnl|CDD|235063
NC_008312.1|WP_011610926.1|1852806_1853136_-|hypothetical-protein	unknown	unknown	gnl|CDD|237177
NC_008312.1|WP_052845753.1|1855866_1857600_-|hypothetical-protein	unknown	unknown	gnl|CDD|224117
NC_008312.1|WP_011610923.1|1844522_1847486_+|hypothetical-protein	unknown	unknown	gnl|CDD|223957

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_008312.1|WP_011610938.1|1869678_1870758_+|PIN/TRAM-domain-containing-protein	gnl|CDD|227292	COG4956, COG4956, Integral membrane protein (PIN domain superfamily) [General function prediction only].	9.43861e-157
NC_008312.1|WP_011610927.1|1853301_1854318_-|hypothetical-protein	gnl|CDD|224117	COG1196, Smc, Chromosome segregation ATPases [Cell division and chromosome partitioning].	9.39723e-07
NC_008312.1|WP_044137207.1|1866981_1867239_-|DUF1830-domain-containing-protein	gnl|CDD|370162	pfam08865, DUF1830, Domain of unknown function (DUF1830). This family of short proteins is functionally uncharacterized.	1.94354e-30
NC_008312.1|WP_011610920.1|1837407_1838166_+|uroporphyrinogen-III-C-methyltransferase	gnl|CDD|235711	PRK06136, PRK06136, uroporphyrinogen-III C-methyltransferase.	6.48093e-149
NC_008312.1|WP_071820548.1|1843886_1844102_+|IS1-family-transposase	gnl|CDD|224576	COG1662, InsB, Transposase and inactivated derivatives, IS1 family [DNA replication, recombination, and repair].	5.65575e-07
NC_008312.1|WP_011610919.1|1833836_1834673_+|diaminopimelate-epimerase	gnl|CDD|178151	PLN02536, PLN02536, diaminopimelate epimerase.	1.91695e-156
NC_008312.1|WP_011610918.1|1833561_1833774_-|hypothetical-protein	gnl|CDD|212463	cd01716, Hfq, bacterial Hfq-like. Hfq, an abundant, ubiquitous RNA-binding protein, functions as a pleiotropic regulator of RNA metabolism in prokaryotes, required for transcription of some transcripts and degradation of others. Hfq binds small RNA molecules called riboregulators that modulate the stability or translation efficiency of RNA transcripts. Hfq binds preferentially to unstructured A/U-rich RNA sequences and is similar to the eukaryotic Sm proteins in both sequence and structure. Hfq forms a homo-hexameric ring similar to the heptameric ring of the Sm proteins.	6.48293e-07
NC_008312.1|WP_044136459.1|1867439_1868708_-|coproporphyrinogen-III-oxidase	gnl|CDD|236007	PRK07379, PRK07379, coproporphyrinogen III oxidase; Provisional.	0
NC_008312.1|WP_011610939.1|1871193_1871847_+|glycosyltransferase	gnl|CDD|275102	TIGR04282, hypothetical_protein, transferase 1, rSAM/selenodomain-associated. Members of this protein family show strongly correlated phylogenetic distribution, and in most cases co-clustering, with an unusual radical SAM enzyme (TIGR04167) whose C-terminal pfam12345 domain often contains a selenocysteine residue. Other members of the conserved gene neighborhood include another putative glycosyltransferase, an alkylhydroperoxidase family protein (TIGR04169), and a phosphoesterase family protein (TIGR04168). The cassette is likely to be biosynthetic but its exact function is unknown. [Unknown function, Enzymes of unknown specificity].	1.1271e-95
NC_008312.1|WP_011610933.1|1862475_1863948_-|hypothetical-protein	gnl|CDD|372732	pfam13809, Tubulin_2, Tubulin like. Many of the residues conserved in Tubulin, pfam00091, are also highly conserved in this family.	1.52779e-08
NC_008312.1|WP_081432405.1|1840226_1840397_-|hypothetical-protein	gnl|CDD|315923	pfam13358, DDE_3, DDE superfamily endonuclease. This family of proteins are related to pfam00665 and are probably endonucleases of the DDE superfamily. Transposase proteins are necessary for efficient DNA transposition. This domain is a member of the DDE superfamily, which contain three carboxylate residues that are believed to be responsible for coordinating metal ions needed for catalysis. The catalytic activity of this enzyme involves DNA cleavage at a specific site followed by a strand transfer reaction.	5.41478e-12
NC_008312.1|WP_011610930.1|1857686_1858649_-|hypothetical-protein	gnl|CDD|224117	COG1196, Smc, Chromosome segregation ATPases [Cell division and chromosome partitioning].	9.64358e-05
NC_008312.1|WP_011610921.1|1838474_1839092_+|molybdenum-cofactor-guanylyltransferase	gnl|CDD|235063	PRK02726, PRK02726, molybdenum cofactor guanylyltransferase.	4.98776e-114
NC_008312.1|WP_011610926.1|1852806_1853136_-|hypothetical-protein	gnl|CDD|237177	PRK12704, PRK12704, phosphodiesterase; Provisional.	0.000242375
NC_008312.1|WP_052845753.1|1855866_1857600_-|hypothetical-protein	gnl|CDD|224117	COG1196, Smc, Chromosome segregation ATPases [Cell division and chromosome partitioning].	1.06891e-05
NC_008312.1|WP_011610923.1|1844522_1847486_+|hypothetical-protein	gnl|CDD|223957	COG1026, COG1026, Predicted Zn-dependent peptidases, insulinase-like [General function prediction only].	0

Protein sequences

>NC_008312.1|WP_011610924.1|1849483_1850875_-|hypothetical-protein
MNSTKITRWKIPLLLFMLIGITTACRPKTYNDLSCDVPLTKGQSPSLDAPPGPINISLNIDGSESMPGYLTNGASRYIKTIQLLDRTFSISDLVEYYRVGGPEKQKISRSKFLEAIKERFYYEDRVTSNLTGAIAPQKEGKELLVLITDLYQNQGDVTAVNKKIRQHYLNKEGYAAGILAIRSEFNGKVYVVGSNRDNFNFPYNTEGKPIEKFRPFYVIFLGPYKHILYYFEKLKRDGGELIKNSEFTIFSPNNIINDLSVMSELKNPGEPISGLKRPFSLNNGKVAIEFPKRKEFELLEIIPNFSKEIPIEYKVNLPILNEYTLPPSANSIKAKISESKYFDESTTEFISSEAIMAKKLFNSMQFSNWEVGKNRDLSYTNTIKPNELPQANIYLFKVDVVANGLGEQDWWQNWNCEDRDCENDGSKTHNLEHFLQGLKSLTNDLMENNPIVLARLCYGIQKN
>NC_008312.1|WP_011610923.1|1844522_1847486_+|hypothetical-protein
MPLLTERTIEVGQKLQGFEVKAITDLKQQRMVAYQLEHIKTGAKLLHLYSEDAENLFSISFPTPPPNSTGVSHILEHSVLAGSKKYPVREPFFEMLKMSPATFINAMTGPDCTYYPVSSKVKQDLFNLAEVYFDAVFHPLLTENTFKREGHHLAPTDKENPTGELKFTGVVYNEMNGAFSDPEQRLDSIANQSLFPDNIYGLESGGNPQNIPELTYKDFRDFHSSYYHPSNAYFVFYGNISTPEYLEFLAKKLEAFERQKPNININPQSRWSEPRFKEDSYPISAADETTQKTYIMIKWLVGDSTDSEEWVALDILSRILLGNEAAPLKKAIVESQIGQDLLGSGVDSVGKEVTFHLGIQGSEPNQGEAFSQLVIKTLKEIAEEDIEPSIVEAAFQQAIYQHQEIGSMYPLRMLFRVMQTWIYSNDPLKFLHISDRLAECKQRYLEKPRYFNNLIREKLLNNPHRLTLVLKPDKEWQSNYDKAVVAQVEQVRSQLTSEELERIATEATELEIESGTPNSPEEIAKLPQLQVKDLPDKPEHIPTDVEELDGQVTLLRNHVLANGVNYLQLDFSLRGLPEDLWLYLSIYIDALRKLGAGEMNYEQVARGIASYTGGISFQSLLRTSTKDAYHSVRGLRVTIKTLDEQIEPALELLHNMIFAVNPRDTARLREVMIQSYSQSNSDLIYNGIYTAILRASAGMTSEAKISEIVNGLPQLELLKKVCDRFDEHGANLMSKVETIRDYVANQPLTASFTGSDNAYNVVKKTLSEWGHQQKQQEGDTFGSRFEPVYNMREALAGPVQVAYCVQTMPAPHFSDERAPFLRLGTHLLGLGYLFTEVRLKGNAYGAGCRYSGLGKVISLYSYRDPHVSRTLDVFAGLIDYLKDVDWTQIDVDRAIIATIQDDSPVLRPEVATSLALERHLIAQTAELREERYQRTLKATVADVKETLLDVFTAGMERSNVCVMSSREKLEEANRSREADPLTISDIM
>NC_008312.1|WP_071820548.1|1843886_1844102_+|IS1-family-transposase
MIQSWTYFLSINDDYKVYTYLIEDCDHKVNKTAMTRVEGEKCRRCYYLTRLHRKTLCYSKSIDMLCKSIVC
>NC_008312.1|WP_081432405.1|1840226_1840397_-|hypothetical-protein
MNYGPRAVVVGDNLPAYKVKGISEAIKTIRTRLIYLSPYSSQFNLIEKWWSSLKAH
>NC_008312.1|WP_011610921.1|1838474_1839092_+|molybdenum-cofactor-guanylyltransferase
MNKSSLAKNYLVALILAGGKSSRMGQDKALIPWKNMPMLERVYQVANKCTEKVYVITPWPEKYKSILPTKCEWLTELKSEGPLVALGQGLTQINSNWILLLGCDLPLLNSDIIETWIAQLNQLSPEILALVPKKYQGWEPLCGFYRQQIKIELENIIGRGDRSFQRLLAQIPVQPLSIDSQTAKMLFNCNTPLDLEVEKGIGNKA
>NC_008312.1|WP_011610920.1|1837407_1838166_+|uroporphyrinogen-III-C-methyltransferase
MNQLKFVGKVYLVGAGPGDPGLITLKGKVLLKQADVVIYDALVSASILEMINPNAEKFNAGKRRDRHSLEQTQTTQLLIEKAKTHAVVVRLKGGDPFVFGRGGEEMEDLMQVGIAVEVIPGVTSGIAAPAYAGIPLTHRNYSSSVTFVTGHEAAGKYRPEVNWEAVAQGAETIVIYMGVHNLQNIIKKLIAAGRDPETPIALIQWGTYPKQKELIGTLNNIVGQIESTGFEAPAITVIGNVVNLHQILGNRE
>NC_008312.1|WP_155994324.1|1835656_1835818_+|hypothetical-protein
MKEVDERNTFFREFKIRLGVDKASRIIKMQMLGQKSRVKDGVQGIFTLVLQQF
>NC_008312.1|WP_155994323.1|1834963_1835116_+|hypothetical-protein
MEGGIYLIQDNDQLVEMTEQAYDSEDQLQEFWETYPNLLAEDDIYRGIPR
>NC_008312.1|WP_011610919.1|1833836_1834673_+|diaminopimelate-epimerase
MTKSFTKYHGLGNDFILIDNRHQLQPILTPEQAIELCDRNFGIGADGVIFALPGVKQTDYTMRIFNSDGSEPEMCGNGIRCLAKFIAELENNNKTKYNIHTGAGIIVPELQGDGQVTVDMGQPRLLASEIPTTLANADDKVVDQLLEVGGKSWFVTCVSMGNPHCITFVEDVTAIDLAKIGPKFEHNPVFPERTNTEFIQVISPKYVKMRVWERGAGATLACGTGACASVVAGVLTQNNERLVTVELPGGCLEIEWSTIDQKIYMTGPAEKVFTGIIA
>NC_008312.1|WP_011610918.1|1833561_1833774_-|hypothetical-protein
MSDFDTSLPSTRQIQTYIQEKKEVEIKLITNDLYVGKVFWQDPNCICLFGQYDSPILIWRQSIVYLKAKN
>NC_008312.1|WP_011610926.1|1852806_1853136_-|hypothetical-protein
MPNCPVCNTEYQQQQVNFCLKCGWYLRLYSNSGDEVLEGSGFSSSDALQKVEKWAIQKLHVLKKQESQLKQLRAKYEELQAELQQSQQERSRLKSELDDYTEKYNQLQT
>NC_008312.1|WP_011610927.1|1853301_1854318_-|hypothetical-protein
MKPDNYSSELTNSVRVTKTLETLPRGWISLSEDELIEAYNYAPRVLSRKAIKVSKIDFRGWRYSNSEVLLGEERNGNYWVMVTEKGCYWLLPKANFRINSFNKDTVKSLFKFNGSLSEDAREFILVKLAKVSLTPGGDQWRLEERGVLDFGGNSQLSRLQSELEGVKEEREKLESELRLARDERDRFASQVAELAYDRLQKTLAKLEEGDRWRSNLTERLERLEQAGALQEQRCSNLEADYFQRLAQLKSELSEKLVQLQSQLSKLEESEINNIYQLQEITHKQKNNTTYLKAVGAEINKINSQILKLKEELQRLLEGELRPIKELVSLFGGWLRNSP
>NC_008312.1|WP_011610928.1|1854402_1855686_-|hypothetical-protein
MWKSIHSWKSTYSLLLSLVLISGSFVACVQLEPEIPPSTSTTSIPLNPDQENLKNSFDDVQKTNNELAAIANNNEEEIKNLNYEKQAIFNQLNQFKNIRRTVIFSFILLVLFTVLLLFYISLLIWQIKQNNAVNKPSNLDTQELVYEVDYKVEDAYYKLEKMSKLWDAETKKIKSQIYYLQQNQQVKTPGNNVDNKKLIVQVVNDKIGEIYRQLQQEIDQRWDIKLRNLQNQINQLQQNQQLKTSDNNADNKKLIFEAVKEEIHGQLQQEIRKRLDIELRNLPNQINQPQQNQQLKTPDNIAGGLPNLEFMLIYKEDTRSLSENAIEVSEADRSMVQPRISSTQAVIIQKVRRGNYWILNEADIDYMVPRHNIKINEYNSKTVANLFECQGYRPEYSGFQLIKPAKVSAISKGETWQLVERGILQFD
>NC_008312.1|WP_052845753.1|1855866_1857600_-|hypothetical-protein
MSGSLVACVQTDPNTILTSPSITSSPLNPDQGNLDQENLKNSFDDIQKTNDEFQTLLDDFIKDIAAVREGSKNRESVNSSKVNEKLIQLEEKVNTYKNQISQIRNQENLEQNFNSINQNISNIKEITEKLKGGLGKDKIGEVQLNLQIITNPEVSYFGRLGPDTQSKINESLTENSKQLKAKIIDLGQVTGLPSSVTLDKDDDKELARKIADLEARNNELAAIAKKNEEEIKNLNSEKQEIYNQLNQFQSRLKLETFVVIIVLVIAVFLSGLCVYIWQDWRRIKLLLKRYNKAYTNTKQPNNGVNQTGDLDTQELVYEVDDKVEDAYDKLEKMSKIWENEAKKIQSQIYYLQQNQQVKTPGNNVDNRKLIVQVVNEKIGEIYRQLQQEIDQRWDIESRNLQNQINQLQQNQKLRTSDNVAGVHRESRITTNHLTSQVTPVPQMNPQIPTHQYFGSSDLQLISMYQHDARSLLKNAIEVSETEQSIDQRRLGGGQGAILQKVRRGNYCILNEGGVDYMVPKNNIKINEHSLETVKNLFECQGYRSGYSGFQLIKPARVSAISRGETWQLVELGVLQFY
>NC_008312.1|WP_011610930.1|1857686_1858649_-|hypothetical-protein
MSNCPQCQAEVNKGDNFCRNCGYALHDSLTGDKPQGFENIRETSAHAATWEHNIKEQLVQMLESFKSQLQELTQKQNNNTASLEAEREEINQINNENSKLQEELQELIQKQNNNTASLEAGREEINQINNEISKLQDELRPIKKLISLFGEWFKNNPEYLPLSTTIDPQVKLQTSTELNTTREVEEEGKYQLPLSEEEQLLKDYKDEEKRTVLSQNAITVSAATESIDNSRLGIGKSVLEKKRRGNYWILKQGSSQYLVPSDTIKINEYSIDTLKNLFECQGVNSEGSKGKFELLKPAKVSSIGEEKWQLSEPGKLEFIG
>NC_008312.1|WP_011610933.1|1862475_1863948_-|hypothetical-protein
MGLYLIGIGGTGAKCVEAVAKLAAIGLFTEEPIKVLFVDADETNGNLARARTSISLYKKTYDLIPTGDKKDCGWMKSKIESFDHWSPFAQEKELRTFFNYNTIKQKQPTLAHLFDVLYTKEEREANLDVGFRGRPAIGAAVMSQVDLDRLEQEPWGRLIEEIQGDTGGGKEAKIFLCGSIFGGTGASGLPTIARLIDNKLKKIKVRDRVQTGCLFVLPYFGFAPTPGENPDGVYARSEQFLLNTEAALRYYVTQGQEIFDQVYLLGNQNLSRVNFSIGKDSQRNDPHFLELYAALAARNFWRDSSTAKGSVILMTRQQSGTISWDDIPDKAEVQPELVNATRFAFTWLAEIAPELEEAKKEKNARFQRLAPWMMEFYQTGSKSGETKPDFSDVDQQEAIGIINNWCEDYLGWLYSLHQCEGDNIALFQADAFPPNKKLAGNELPNLIVGDSRDKGKKSRDTVKKLKDGLKATPPGGTIGLAKSVYMASRI
>NC_008312.1|WP_044137207.1|1866981_1867239_-|DUF1830-domain-containing-protein
MTIALDRLPKQQSQKILCFYGNNTRKMQIARVSSVENKYWERTVFPGERFLFEATPEAELEIHQTQENGEIKSESFSCKGLKVDE
>NC_008312.1|WP_044136459.1|1867439_1868708_-|coproporphyrinogen-III-oxidase
MVKRPVGNYCIPSSAYVHIPFCRRRCYYCDFPISVVGDGKKGDNFSPIQEYVEVICQEISTTKSFDQPLKTIFFGGGTPSLLSVGQLSRILDALEQKFGIVANAEISIEMDPGTFDLEQVQGYKFLGVNRVSLGVQAFQDDLLQVCGRLHNVSDIYKAVNTLHQAGIINFSIDLISGLPHQTLEQWQISLLSGIAISPTHISSYDLVLEKVTAFGHYYKPGHAPLPTDETAAEMYRIAQQLISISGYEHYEISNYAKQGYQCSHNRVYWENHPYYGFGMGAASYLEGQRFTRPRTRKKYYQWVLSFQDHSLESQGINASNQDFLLETLMLGFRLAQGINVLTLSQQFGQKTVEKLLIYLQPYQKLGWVEFINQKGVATPFSDNQKLPIEGHLRLTDPEGFLFSNTVLSTLFSKISNSISMKC
>NC_008312.1|WP_011610938.1|1869678_1870758_+|PIN/TRAM-domain-containing-protein
MLDALIIISFVFAGAGIGFYSIELLPPNVLLEVTNIEGLRSVLSAFTSLIGFVVGLVFQTTYRRVEIKFRQMPVDLLLTRAIGLIIGLLVANLMLAPLFLLPIPDEFSFIKPLVAVLASVMLGFTGVNVADTHGRGFLRLINPNSLDAVLVAEGTLKPSTTKILDTSCIIDGRIESLLKTGFLEGQILVPNFVLQELQLIADASNDQKRVRGRRGLDILNRLKELYPSQIQIHFADYEEIPTVDAKLVRFALEINGTLLTNDYNLSKVASLQKVPVLNINDLTQAVRPSYLPGDTIEIKIRKEGKEPSQGIGYLDDGTMVVVESGSGYVGDEVRVIVTSSLQTSAGRMIFARTQESAIA
>NC_008312.1|WP_011610939.1|1871193_1871847_+|glycosyltransferase
MKNQQLIIFTRYPEPGTTKTRLIPVLGAKGAANLQFHMTETTVIKAKKLSNMMALLVEVRFAGGNLQLMKNWLGVELNLKYQKQGTGDLGERMARAFESAFYQEMESVVIIGTDCPSLTVDIMLEAFAKLTEYDVIIGPATDGGYYLIGLKKIIPELFQGINWGTSEVLSKTMAIAQNLNLDIHYLPKLSDIDRPEDLEKLQFEIHQDLRKDTIYST

Crispr_ID: NC_008312_15

• CRISPR_ID: NC_008312_15
• CRISPR_location: 1921946-1922051
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NC_008312_15

Consensus_repeat	Method
GAATACTTCTTTTATCCCTTTGAAA	CRISPRCasFinder

spacers of NC_008312_15

>15.1|1921971|56|NC_008312|CRISPRCasFinder
GGGCAGGTTTAAGACCTGACTTTTTGGTAATTAATTAACATATTAACAAATATGAC

CRISPR arrays and Neighbor proteins around NC_008312_15

CRISPR arrays

The CRISPR arrays of NC_008312_15

>merge|NC_008312|15|1921946-1922051|CRISPRCasFinder
GAATACTTCTTTTATCCCTTTGAAAGGGCAGGTTTAAGACCTGACTTTTTGGTAATTAATTAACATATTAACAAATATGACGAATACTTCTTTTATCCCTTTAAAA

>NC_008312|15|12|1921946-1922051|CRISPRCasFinder
GAATACTTCTTTTATCCCTTTGAAA	GGGCAGGTTTAAGACCTGACTTTTTGGTAATTAATTAACATATTAACAAATATGAC
GAATACTTCTTTTATCCCTTTAAAA

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_008312.1|WP_011610968.1|1919536_1919836_-|heat-shock-70kD-protein-12B	unknown	unknown	gnl|CDD|212671
NC_008312.1|WP_011610974.1|1934395_1935022_+|DnaJ-domain-containing-protein	unknown	unknown	gnl|CDD|223560
NC_008312.1|WP_011610963.1|1908789_1910424_+|HD-domain-containing-protein	unknown	unknown	gnl|CDD|225116
NC_008312.1|WP_011610979.1|1944501_1944867_-|phage-holin-family-protein	unknown	unknown	gnl|CDD|224861
NC_008312.1|WP_011610970.1|1922202_1922877_+|J-domain-containing-protein	unknown	unknown	gnl|CDD|223560
NC_008312.1|WP_011610967.1|1917667_1919488_-|Hsp70-family-protein	unknown	unknown	gnl|CDD|212671
NC_008312.1|WP_011610961.1|1904237_1905296_+|photosystem-II-D2-protein-(photosystem-q(a)-protein)	unknown	unknown	gnl|CDD|130222
NC_008312.1|WP_011610972.1|1930018_1930708_+|ATP-dependent-Clp-protease-proteolytic-subunit	unknown	unknown	gnl|CDD|183588
NC_008312.1|WP_155994328.1|1943206_1943395_+|hypothetical-protein	unknown	unknown	unknown
NC_008312.1|WP_011610960.1|1902053_1902320_-|hypothetical-protein	unknown	unknown	gnl|CDD|184240
NC_008312.1|WP_011610965.1|1914920_1915883_+|cysteine-synthase-A	unknown	unknown	gnl|CDD|273465
NC_008312.1|WP_011610976.1|1938099_1939044_+|calcium/sodium-antiporter	unknown	unknown	gnl|CDD|223604
NC_008312.1|WP_044136478.1|1942928_1943162_+|winged-helix-turn-helix-domain-containing-protein	unknown	unknown	gnl|CDD|379282
NC_008312.1|WP_011610973.1|1930922_1931513_+|ATP-dependent-Clp-endopeptidase-proteolytic-subunit-ClpP	unknown	unknown	gnl|CDD|178955
NC_008312.1|WP_011610966.1|1916944_1917445_-|hypothetical-protein	unknown	unknown	unknown
NC_008312.1|WP_011610975.1|1935766_1937014_+|FkbM-family-methyltransferase	unknown	unknown	gnl|CDD|273628
NC_008312.1|WP_011610962.1|1907659_1907941_+|4a-hydroxytetrahydrobiopterin-dehydratase	unknown	unknown	gnl|CDD|234845
NC_008312.1|WP_011610964.1|1911567_1913487_+|iron-uptake-porin	unknown	unknown	gnl|CDD|335962
NC_008312.1|WP_011610969.1|1919853_1921656_-|hypothetical-protein	unknown	unknown	gnl|CDD|130902
NC_008312.1|WP_011610971.1|1926210_1927449_-|VWA-domain-containing-protein	unknown	unknown	gnl|CDD|225187

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_008312.1|WP_011610968.1|1919536_1919836_-|heat-shock-70kD-protein-12B	gnl|CDD|212671	cd10229, HSPA12_like_NBD, Nucleotide-binding domain of HSPA12A, HSPA12B and similar proteins. Human HSPA12A (also known as 70-kDa heat shock protein-12A) and HSPA12B (also known as 70-kDa heat shock protein-12B, chromosome 20 open reading frame 60/C20orf60, dJ1009E24.2) belong to the heat shock protein 70 (HSP70) family of chaperones that assist in protein folding and assembly, and can direct incompetent "client" proteins towards degradation. Typically, HSP70s have a nucleotide-binding domain (NBD) and a substrate-binding domain (SBD). The nucleotide sits in a deep cleft formed between the two lobes of the NBD. The two subdomains of each lobe change conformation between ATP-bound, ADP-bound, and nucleotide-free states. ATP binding opens up the substrate-binding site; substrate-binding increases the rate of ATP hydrolysis. HSP70 chaperone activity is regulated by various co-chaperones: J-domain proteins and nucleotide exchange factors (NEFs). No co-chaperones have yet been identified for HSPA12A or HSPA12B. The gene encoding HSPA12A maps to 10q26.12, a cytogenetic region that might represent a common susceptibility locus for both schizophrenia and bipolar affective disorder; reduced expression of HSPA12A has been shown in the prefrontal cortex of subjects with schizophrenia. HSPA12A is also a candidate gene for forelimb-girdle muscular anomaly, an autosomal recessive disorder of Japanese black cattle. HSPA12A is predominantly expressed in neuronal cells. It may also play a role in the atherosclerotic process. The gene encoding HSPA12B maps to 20p13. HSPA12B is predominantly expressed in endothelial cells, is required for angiogenesis, and may interact with known angiogenesis mediators. It may be important for host defense in microglia-mediated immune response. HSPA12B expression is up-regulated in lipopolysaccharide (LPS)-induced inflammatory response in the spinal cord, and mostly located in active microglia; this induced expression may be regulated by activation of MAPK-p38, ERK1/2 and SAPK/JNK signaling pathways. Overexpression of HSPA12B also protects against LPS-induced cardiac dysfunction and involves the preserved activation of the PI3K/Akt signaling pathway.	1.26952e-19
NC_008312.1|WP_011610974.1|1934395_1935022_+|DnaJ-domain-containing-protein	gnl|CDD|223560	COG0484, DnaJ, DnaJ-class molecular chaperone with C-terminal Zn finger domain [Posttranslational modification, protein turnover, chaperones].	6.45829e-16
NC_008312.1|WP_011610963.1|1908789_1910424_+|HD-domain-containing-protein	gnl|CDD|225116	COG2206, COG2206, c-di-GMP phosphodiesterase class II (HD-GYP domain) [Signal transduction mechanisms].	1.16593e-26
NC_008312.1|WP_011610967.1|1917667_1919488_-|Hsp70-family-protein	gnl|CDD|212671	cd10229, HSPA12_like_NBD, Nucleotide-binding domain of HSPA12A, HSPA12B and similar proteins. Human HSPA12A (also known as 70-kDa heat shock protein-12A) and HSPA12B (also known as 70-kDa heat shock protein-12B, chromosome 20 open reading frame 60/C20orf60, dJ1009E24.2) belong to the heat shock protein 70 (HSP70) family of chaperones that assist in protein folding and assembly, and can direct incompetent "client" proteins towards degradation. Typically, HSP70s have a nucleotide-binding domain (NBD) and a substrate-binding domain (SBD). The nucleotide sits in a deep cleft formed between the two lobes of the NBD. The two subdomains of each lobe change conformation between ATP-bound, ADP-bound, and nucleotide-free states. ATP binding opens up the substrate-binding site; substrate-binding increases the rate of ATP hydrolysis. HSP70 chaperone activity is regulated by various co-chaperones: J-domain proteins and nucleotide exchange factors (NEFs). No co-chaperones have yet been identified for HSPA12A or HSPA12B. The gene encoding HSPA12A maps to 10q26.12, a cytogenetic region that might represent a common susceptibility locus for both schizophrenia and bipolar affective disorder; reduced expression of HSPA12A has been shown in the prefrontal cortex of subjects with schizophrenia. HSPA12A is also a candidate gene for forelimb-girdle muscular anomaly, an autosomal recessive disorder of Japanese black cattle. HSPA12A is predominantly expressed in neuronal cells. It may also play a role in the atherosclerotic process. The gene encoding HSPA12B maps to 20p13. HSPA12B is predominantly expressed in endothelial cells, is required for angiogenesis, and may interact with known angiogenesis mediators. It may be important for host defense in microglia-mediated immune response. HSPA12B expression is up-regulated in lipopolysaccharide (LPS)-induced inflammatory response in the spinal cord, and mostly located in active microglia; this induced expression may be regulated by activation of MAPK-p38, ERK1/2 and SAPK/JNK signaling pathways. Overexpression of HSPA12B also protects against LPS-induced cardiac dysfunction and involves the preserved activation of the PI3K/Akt signaling pathway.	3.42148e-57
NC_008312.1|WP_011610961.1|1904237_1905296_+|photosystem-II-D2-protein-(photosystem-q(a)-protein)	gnl|CDD|130222	TIGR01152, Photosystem_II_D2_protein, Photosystem II, DII subunit (also called Q(A)). This model describes the Photosystem II, DII subunit (also called Q(A)) in bacterial and its equivalents in chloroplast of algae and higher plants. Photosystem II is in many ways functionally equivalent to bacterial reaction center. At the core of Photosystem II are several light harvesting cofactors including plastoquinones, pheophytins, phyloquinones etc. These cofactors are intimately associated with the polypeptides, which principally including subunits DI, DII, Cyt.b, Cyt.f and iron-sulphur protein. Together they participate in the electron transfer reactions that lead to the net production of the reducting equivalents in the form of NADPH, which are used for reduction of CO2 to carbohydrates(C6H1206). Phosystem II operates during oxygenic photosynthesis and principal electron donor is H2O. Although no high resolution X-ray structural data is presently available, recently a 3D structure of the supercomplex has been described by cryo-electron microscopy. Besides a huge body of literature exits that describes function using a variety of biochemical and biophysical techniques. [Energy metabolism, Electron transport, Energy metabolism, Photosynthesis].	0
NC_008312.1|WP_011610972.1|1930018_1930708_+|ATP-dependent-Clp-protease-proteolytic-subunit	gnl|CDD|183588	PRK12552, PRK12552, ATP-dependent Clp protease proteolytic subunit.	8.42013e-163
NC_008312.1|WP_011610979.1|1944501_1944867_-|phage-holin-family-protein	gnl|CDD|224861	COG1950, COG1950, Predicted membrane protein [Function unknown].	2.7918e-18
NC_008312.1|WP_011610960.1|1902053_1902320_-|hypothetical-protein	gnl|CDD|184240	PRK13683, PRK13683, hypothetical protein; Provisional.	3.90886e-45
NC_008312.1|WP_011610970.1|1922202_1922877_+|J-domain-containing-protein	gnl|CDD|223560	COG0484, DnaJ, DnaJ-class molecular chaperone with C-terminal Zn finger domain [Posttranslational modification, protein turnover, chaperones].	1.17271e-25
NC_008312.1|WP_011610976.1|1938099_1939044_+|calcium/sodium-antiporter	gnl|CDD|223604	COG0530, ECM27, Ca2+/Na+ antiporter [Inorganic ion transport and metabolism].	1.30101e-56
NC_008312.1|WP_044136478.1|1942928_1943162_+|winged-helix-turn-helix-domain-containing-protein	gnl|CDD|379282	pfam13592, HTH_33, Winged helix-turn helix. This helix-turn-helix domain is often found in transferases and is likely to be DNA-binding.	8.17753e-06
NC_008312.1|WP_011610973.1|1930922_1931513_+|ATP-dependent-Clp-endopeptidase-proteolytic-subunit-ClpP	gnl|CDD|178955	PRK00277, clpP, ATP-dependent Clp protease proteolytic subunit; Reviewed.	9.14803e-137
NC_008312.1|WP_011610969.1|1919853_1921656_-|hypothetical-protein	gnl|CDD|130902	TIGR01843, Hemolysin_secretion_protein_D_plasmid, type I secretion membrane fusion protein, HlyD family. Type I secretion is an ABC transport process that exports proteins, without cleavage of any signal sequence, from the cytosol to extracellular medium across both inner and outer membranes. The secretion signal is found in the C-terminus of the transported protein. This model represents the adaptor protein between the ATP-binding cassette (ABC) protein of the inner membrane and the outer membrane protein, and is called the membrane fusion protein. This model selects a subfamily closely related to HlyD; it is defined narrowly and excludes, for example, colicin V secretion protein CvaA and multidrug efflux proteins. [Protein fate, Protein and peptide secretion and trafficking].	0.00701294
NC_008312.1|WP_011610975.1|1935766_1937014_+|FkbM-family-methyltransferase	gnl|CDD|273628	TIGR01444, 2-O-methyltransferase_NoeI, methyltransferase, FkbM family. Members of this family are characterized by two well-conserved short regions separated by a variable in both sequence and length. The first of the two regions is found in a large number of proteins outside this subfamily, a number of which have been characterized as methyltransferases. One member of the present family, FkbM, was shown to be required for a specific methylation in the biosynthesis of the immunosuppressant FK506 in Streptomyces strain MA6548.	2.51244e-24
NC_008312.1|WP_011610962.1|1907659_1907941_+|4a-hydroxytetrahydrobiopterin-dehydratase	gnl|CDD|234845	PRK00823, phhB, pterin-4-alpha-carbinolamine dehydratase; Validated.	9.07031e-38
NC_008312.1|WP_011610964.1|1911567_1913487_+|iron-uptake-porin	gnl|CDD|335962	pfam04966, OprB, Carbohydrate-selective porin, OprB family.	1.16142e-31
NC_008312.1|WP_011610965.1|1914920_1915883_+|cysteine-synthase-A	gnl|CDD|273465	TIGR01139, Cysteine_synthase, cysteine synthase A. This model distinguishes cysteine synthase A (CysK) from cysteine synthase B (CysM). CysM differs in having a broader specificity that also allows the use of thiosulfate to produce cysteine thiosulfonate. [Amino acid biosynthesis, Serine family].	4.76052e-173
NC_008312.1|WP_011610971.1|1926210_1927449_-|VWA-domain-containing-protein	gnl|CDD|225187	COG2304, COG2304, Uncharacterized protein containing a von Willebrand factor type A (vWA) domain [General function prediction only].	7.63218e-61

Protein sequences

>NC_008312.1|WP_011610969.1|1919853_1921656_-|hypothetical-protein
MEKFLPNKKNWFQHLAEGFSDFFWGTRSARMSSETLRINNDNLIEYYEKRDSIQQQIQIAQIQLKTVMEERNFQFQYEQGNLNRQFQAQQGELNRQLQTELGTINRLFQAEEGKLNRELQTELARLNREHQIQEGKLNRENAHQLELFRAQLQIFLQEKQKDLQLQLKEIDATLARELKAIDLQNNLTVIRQQRRLNNWPLTLDDEQIKEIVKSDNLLILFVPPILKYDRAGAGANSQPNTFPDIEQGLNRRLRAFLEKYKQTGRKVDFLTGAWMTKALSGEGAFKTIFSGLKSKPMLVINTLVERTYYHLEYSYWSQNFPEPYIDSLPKEDPLSWLELLYFAVKERLLKWEKQRNQEKIETGTTEEFDADWGEEVVKKFLADLQLIKREKRLLERGQDPNNLPNRNYTVLDSDKETFSRFIAIQVSLLIGRTADAYFLLDVPPQERKRPLLPELLPNLLEEIPSEEREKIIEYLVYFYQSLYQQLGEEESAWVPEMLIDFASSLIYLDNKFWAKEQIEKSVESWLLMRGIKSLDQVSNLEVMKYVLVSGDDEYLDRLNQFILLLGRENYVIIAETLLDTWRKLKIKGCIGVDGHGQTLF
>NC_008312.1|WP_011610968.1|1919536_1919836_-|heat-shock-70kD-protein-12B
MDKSFEVVVAIDFGTSRSGFAYKFKESDVSVFRDLWPDNPMSYPKTATYLLLSSTGEVEAWGYTAMKKLAQFRAQGTAKDYYFTRNFKMELHSGKKDES
>NC_008312.1|WP_011610967.1|1917667_1919488_-|Hsp70-family-protein
MIAKYIRLIKDEALKEIKNSTSGELKDQEIRWCLSIPAIWKNEDKDLMRRAARKAGLINSSDDEAERLFLVLEPEAAAIFCQEEDKNALTPGNKIMIIDCGGGTVDITVHKLVKDGGLDEVAPGTGGPFGSIYVDKSFQEYLTEKLSAEMVKGFHDQDPVGYLKMMEEWERTKCNFDPETSGDVIYFNIPTRLYNFISKRKAKILEQLADEQNGDDENIHLSYSTMENIFRITVHKLVKDGGLDEVAPGTGGPFGSIYVDKSFQEYLTEKLSAEMVKGFHDQEPVDYLKMMEEWERTKCNFDPETSGDVIYFNIPTRLYNFISKRKAKILEQLADEQNGDDKNIHLSYSTMENIFRPTLDGLVSTVKNQFKELGDEEVDIIFLVGGFSTSPVLRQRIKKEFGSKAKKIVMPPRPGVAILKGAASFGVAPGIIRARRSRLTYGVSSSREFNQFKDTIISQKQQSDNPENWENCLRVYKNNNDFLNWLLNNFDIQYSNHNHEQEKQQINSLKNALKNPKKLLEKFYNIYLMIVEPKKRYNQKHKQELKETVYLLNQKIQSQEILINELKRENEKLRKLKSSLLSKLSDRDRDTSNTITSDESRPQRDV
>NC_008312.1|WP_011610966.1|1916944_1917445_-|hypothetical-protein
MKNSILTDLQIPEAAKFPEPIPTNLKNLVEKGLKLVKEIVNDDPPGHFLIANPGEIFNPENHEPVPSCEPSGQIVYTTYPGYSVNNRIIGESLKAFVFTEPNKQPEGQEEQPFENNQNHQQPNSIENEQQSPSNQQLKPTSNHQSPVPQTSENNQNNQQPSSIENQ
>NC_008312.1|WP_011610965.1|1914920_1915883_+|cysteine-synthase-A
MRIAHNITELVGRTPLVQLNSIPKAEGCLAKIIVKLEGMNPAASVKDRIGVNMINVAEREGLIKPGKTTLVEPTSGNTGIALAMVAAARGYKLILTMPETMSMERRVMLRAYGAELVLTPGSEGMKGAITKAQEIVDLSSNGYYMLQQFQNPANPEIHSKTTALEIWEDTDGKVDILVAGVGTGGTVTGVAETIKARKPEFQAIAVEPSNSPVLSGGKPGPHKIQGIGAGFVPDVLDTKIIDEVIQVPDSEAMVYGRRIAKEEGILSGISTGAALCAAIEVGKRPENDGKLIVMIQPSFGERYLSTPLFQELGPTLAEVR
>NC_008312.1|WP_011610964.1|1911567_1913487_+|iron-uptake-porin
MSKTFWYCLILSPAVLGATLVASSYALATENKQTNTVIQPQAATTENISINNNIDIQEPDLLAQVTATNSTNSVGNTPATTIRQINRYGREGRNLRRPGLRNITNNRKPIKGQVTSVSQLSDVQPTDWAFQALQSLVERYGCIVGYPDGTYRGNRALTRFEFAAGVNACLDRVMELLQAAIEDTVSREDLAILQRLQEEFSAELAILRGRVDALEARAAELEANQFSTTTKLRGEVIFALVDNFEDQGKYGAFGDTIQDEDQTVFQYRVRLNFNTSFSGEDLLFTRLQAGNAQAFNQKIAESEGQQTFNILDRTDDTLQLDKLFYKFPVRDNIRVTIAANKVSWYDFVPTLNPYMEDFDGGSGSLSAFGQRNPIYRLGGGKGLGVEYDFGCKDQYACTYSPFSVSFGYLAAEGENPSQGKGLFNGDYAALAQLTFTPIRNFQVGLTYNKGYFGPGNFGFDDGAATGLGDNGSLNSGFVGTGIANSVYGLNAGLNDRRPGSVNINKSVSTNAYGVEMSWRAADWVTINGFGTYLDGKLIGKGDFEIWTYGATIAFPDLLKEGSLAGIVVGREPYLNDLELPSGLDSGLRQDMSWHLEAFYKYQLTDYISITPGVTVITNANQDDDNDELIIGTIRTTFQF
>NC_008312.1|WP_011610963.1|1908789_1910424_+|HD-domain-containing-protein
MIQLNTLKLFQELTETSELLIIEQLLDIGVALSDTYNLGELLNLILSKSREITCSDAGSVYLVDEVNFKERKLVFKVAQNDSIPELAFQEIALPIDFKSLTGYVALTGHTLNIPDAYNLPKDIPYKFDESFDEKTGYRTCSVLILPVQKQNQEIIGVLQLINRKVQPDVVITKENAKELTKAYSKWEQRILISLASQAAISIERNNLQENIENLFEGFVKASVQAIEARDSCTSGHSERVAKLTVGLCQEVNIITNGVFSGTYFSNEQIQEMRYAALLHDFGKIGVPEGILTKRKKLYQEQLELIKQRFSVAQRTLEMESAQTKYEYLLRHLSGTYQSHTQESCPLCQKIENLDLELKTAITQLNNYWQTILIANEPKVLAEEPLKQLQQISLYTYKDTDGQIKPLITSEEMAQLTVPRGNLTPEERRAVEAHVTHSYEFLKQIAWTKNLQNIPEIAYGHHEKLDGSGYPRGLKKNEISLQTQIIVIADIYDALTAGDRPYKQGLPVEAALRIMRSEAAENKINSHFLELFEQKQVFSILGHSK
>NC_008312.1|WP_011610962.1|1907659_1907941_+|4a-hydroxytetrahydrobiopterin-dehydratase
MTELLAVEEINQRISQISDWKLEGNKLKYIKTVKNFVEAINFVNKLVAPAEASQHHPDLEVSYNKVTIILTTHNSGGLTEKDFKMAKTISGLS
>NC_008312.1|WP_011610961.1|1904237_1905296_+|photosystem-II-D2-protein-(photosystem-q(a)-protein)
MTVAVGRPQSQRGAFDVLDDWLKRDRFVFVGWSGILLFPCAFLSIGGWLTGTTFVTSWYTHGLASSYLEGCNFLTVAISSPAYSMGHSLLFLWGPEAQWDFARWCQIGGLWSFTALHGAFALIGFCLRQIEIARLVGIRPYNAIAFTGPIAVFVSVFLMYPLGQSSWFFAPSFGVAGIFRFILFLQGFHNWTLNPFHMMGVAGILGGALLCAIHGATVENTLFQDGEAANTFRAFEPTQSEETYSMVTANRFWSQIFGIAFSNKRWLHFFMLFVPVTGLWMSSIGIVGLAFNLRAYDFVSQELRAADDPEFETFYTKNILLNEGIRAWMSPADQPHQNFMFPEEVLPRGNAL
>NC_008312.1|WP_011610960.1|1902053_1902320_-|hypothetical-protein
MFTIDIIVKYTPVPFSIQRKSAEDAESTYEQIVESIRSGNPQILELTCEKIPEKKIAVVMSEVSGVQISQKSGAAATGRPPGFVTVAQ
>NC_008312.1|WP_011610970.1|1922202_1922877_+|J-domain-containing-protein
MVSSDYYKILNVHPTATQGQIRQAYRRLVKLFHPDTNTEVANHERIISINEAYEVLSDPQQRKSYDQQLNQNYQRYRNISQDYYKHNKRRQNIDEHLQRWINHVYRPVDTIIIQILKPLKNEIDDLAADPFDDQLLESFQDYLETSRGLLKKAHNLFSSQPNPSNFAGVAAHLYYCLNQVSDGIEDLELFTLNYDDYYLHTGQELFRIADKLRQEAQAAIKGIF
>NC_008312.1|WP_011610971.1|1926210_1927449_-|VWA-domain-containing-protein
MKVNLRSALNDTNIDASQSLSQRQVALSISVMANQLERTVPLNLCLILDHSGSMEGRPLETVKQAAVQLVEKLKEGDRLSVVAFDHQAQVIVPNQMINDSASIKGKINKLRASGGTAIDKGLKLGIEELNKGRKESISQAFILTDGENEHGDNDLCLKLAKLATDYNITLNSLGFGDDWNQDVLEKIADAGGGNLSYIQQPEQAIEEFSKLFNRIKSVGITNSYLQFYLMPKVRLAELKPIAQVAPDTIELPVKKEGNGFIVRLGDLMKDIERVVLVNTYIGQLPEGKQAIAQLQIRYDDPAQNQEGLLSESILVEANFMEKYQPQVNSQVQNHILALAKYRQTQIAETKLQQGDRAGAATMLQTAAKTALQMGDTGAATVLQTSATRLQDGDKLSEMERKKTRIVSKTILK
>NC_008312.1|WP_011610972.1|1930018_1930708_+|ATP-dependent-Clp-protease-proteolytic-subunit
MKSPIKAVQTSSYYGDVSFRTPPPDLESLMLKERIVYLGLPLFSSDEVKRNVGIDVTQLIIAQLLYLQFDNPEKPIYFYINSTGTSWYTGDAIGFETEAFAICDTMSYVKPPIHTICIGQAMGTAAMILSAGTKGYRASLPHATIVLNQAKTGARGQATDISIRAKEVLVNKTTFLDILSKNTGQSVEKIAKDTDRMLYMTPEIAKEYGLIDQVLASRKELPKPLPANV
>NC_008312.1|WP_011610973.1|1930922_1931513_+|ATP-dependent-Clp-endopeptidase-proteolytic-subunit-ClpP
MPIGIPSVPYRLPGSQYERWIDIYTRLGQERIIFLGQEVTDGLANRIVAYMLYLDSDDPNKPIYLYINSPGGSVTAGLAIYDTMQYIKADVITICLGLAASMGSFLLAAGTKGKRLALPNSRIMIHQPMGGTRGQATDIEIEANEILRVRSELNNMLAERTGQSLEKIEKDTDRDYYMSAEEAKEYGLIDQVIEER
>NC_008312.1|WP_011610974.1|1934395_1935022_+|DnaJ-domain-containing-protein
MNIADYYRKLDLNLGASLGEVKASYRRLARMYHPDVNPKDKHAKDKFIAVTEAYKILLRVAPAQAELPYNLTPTSTTNKNSKSETVSPRETKVRRTVKQKQNQNKSHTLEVERQLKQNYYLQLKHLLKYKRYPRAIALAEGLAQRMPQDPEVRQWQAIAYQRWGRQLINERKLDKARNYLKKALKTDPQNRDLWAEIEYDFHQLEKIY
>NC_008312.1|WP_011610975.1|1935766_1937014_+|FkbM-family-methyltransferase
MTDINQEFQRALKFQKEGKLQEAESIYINILKSDSDHVASLINLGLIEQSQGKLEEATQFYKYAFQIDSNNISLLYLLARITQELNQLDEAINYWQKLVQLKPDGTLEFYGNIGNSLVQQGKFDEALNCFRDALKISPNSFQAHQAIGNLLIRKEQLLEAKLEFSKALEINPNYQTAKIWLTLVDKLLKGENIVSFNYQSTPIKFEITGKNLAVEIANVGGTFYELPELEFIRQNLKSSNPVIVDIGANTGNHLVYFAKIMQASKVIPIEFHPDILATLKKHISINQVSNIDLSILGYAIGENSGTSFIKEHPAKDLCLTEIDNNIINGTKVEVMTLDDLIKEKVDFIKVDVQGTEVKALTGAKNLISIYQPDMLVEVAKNHMKDFRKFLEAVKYQTVKAFDHGRYVNFYIQHTK
>NC_008312.1|WP_011610976.1|1938099_1939044_+|calcium/sodium-antiporter
MPNLIIWLIIFIVSLFVLIKASDFFTDAAEKIGISLGISPFLVGVTIVSIGTSLPELVSSIIAVYQNSSEIVFGNVMGSNIANIFLIIGTASLISSPLKILYELINVDLPLFVGSAFLLGLTVLDSNFSINEAIICILGYIVYVFYAISSGKEEQQSETIDTSQKSFPVKQIVILIISSLFIFFGATYTIKSVTKISEILEVGKELIALSAVALGTSLPELIVTISAARKGNPEIAVGNVLGSNIFNSLMVMGIPRLTGKLEIPDDVLDSGLLVLLVGTILFFFVTQDKQVTRWEGLIFFIFYGWFIGNIFGLV
>NC_008312.1|WP_044136478.1|1942928_1943162_+|winged-helix-turn-helix-domain-containing-protein
MILKELPRDYVVDRNIWRGKIISNVIELRWGVKLKTTRIYKILNELNLSAQKAHINYANASQEQQKTFILSLKKIGI
>NC_008312.1|WP_155994328.1|1943206_1943395_+|hypothetical-protein
MSAQVFFTDGQKKNTAPEVPSNEKGFINKLNGMISVDAFTAQEYLKLKEKSKTEEVSDDFLQ
>NC_008312.1|WP_011610979.1|1944501_1944867_-|phage-holin-family-protein
MSILQLLILWFVTAVSLFIISKLPTGVEIDDFKIALISSVVFGFLNALVRPVLVAVVFPIKIVLSSFLFTLLLNMSIFGLAAWLVSGFRLRWGFWSALIGSVALGFINSFLYELLNRVVVS

Crispr_ID: NC_008312_16

• CRISPR_ID: NC_008312_16
• CRISPR_location: 1930655-1930752
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NC_008312_16

Consensus_repeat	Method
CAAGTTTTAGCAAGTAGAAAAGAACTA	CRISPRCasFinder

spacers of NC_008312_16

>16.1|1930682|44|NC_008312|CRISPRCasFinder
CCAAAACCTTTACCTGCTAATGTTTAAGTGATAAACAAAATTAA

CRISPR arrays and Neighbor proteins around NC_008312_16

CRISPR arrays

The CRISPR arrays of NC_008312_16

>merge|NC_008312|16|1930655-1930752|CRISPRCasFinder
CAAGTTTTAGCAAGTAGAAAAGAACTACCAAAACCTTTACCTGCTAATGTTTAAGTGATAAACAAAATTAACAAGTTTTGGCAAGTAGAAAAGAACTA

>NC_008312|16|13|1930655-1930752|CRISPRCasFinder
CAAGTTTTAGCAAGTAGAAAAGAACTA	CCAAAACCTTTACCTGCTAATGTTTAAGTGATAAACAAAATTAA
CAAGTTTTGGCAAGTAGAAAAGAACTA

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_008312.1|WP_011610968.1|1919536_1919836_-|heat-shock-70kD-protein-12B	unknown	unknown	gnl|CDD|212671
NC_008312.1|WP_081432408.1|1951618_1951768_+|hypothetical-protein	unknown	unknown	gnl|CDD|279973
NC_008312.1|WP_011610974.1|1934395_1935022_+|DnaJ-domain-containing-protein	unknown	unknown	gnl|CDD|223560
NC_008312.1|WP_011610963.1|1908789_1910424_+|HD-domain-containing-protein	unknown	unknown	gnl|CDD|225116
NC_008312.1|WP_011610967.1|1917667_1919488_-|Hsp70-family-protein	unknown	unknown	gnl|CDD|212671
NC_008312.1|WP_011610969.1|1919853_1921656_-|hypothetical-protein	unknown	unknown	gnl|CDD|130902
NC_008312.1|WP_155994328.1|1943206_1943395_+|hypothetical-protein	unknown	unknown	unknown
NC_008312.1|WP_011610979.1|1944501_1944867_-|phage-holin-family-protein	unknown	unknown	gnl|CDD|224861
NC_008312.1|WP_011610973.1|1930922_1931513_+|ATP-dependent-Clp-endopeptidase-proteolytic-subunit-ClpP	unknown	unknown	gnl|CDD|178955
NC_008312.1|WP_011610970.1|1922202_1922877_+|J-domain-containing-protein	unknown	unknown	gnl|CDD|223560
NC_008312.1|WP_011610976.1|1938099_1939044_+|calcium/sodium-antiporter	unknown	unknown	gnl|CDD|223604
NC_008312.1|WP_044136478.1|1942928_1943162_+|winged-helix-turn-helix-domain-containing-protein	unknown	unknown	gnl|CDD|379282
NC_008312.1|WP_011610986.1|1954985_1955288_+|helix-turn-helix-domain-containing-protein	unknown	unknown	gnl|CDD|379256
NC_008312.1|WP_011610966.1|1916944_1917445_-|hypothetical-protein	unknown	unknown	unknown
NC_008312.1|WP_011610975.1|1935766_1937014_+|FkbM-family-methyltransferase	unknown	unknown	gnl|CDD|273628
NC_008312.1|WP_011610962.1|1907659_1907941_+|4a-hydroxytetrahydrobiopterin-dehydratase	unknown	unknown	gnl|CDD|234845
NC_008312.1|WP_011610964.1|1911567_1913487_+|iron-uptake-porin	unknown	unknown	gnl|CDD|335962
NC_008312.1|WP_011610965.1|1914920_1915883_+|cysteine-synthase-A	unknown	unknown	gnl|CDD|273465
NC_008312.1|WP_011610980.1|1944893_1945985_-|redox-regulated-ATPase-YchF	unknown	unknown	gnl|CDD|236583
NC_008312.1|WP_011610971.1|1926210_1927449_-|VWA-domain-containing-protein	unknown	unknown	gnl|CDD|225187

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_008312.1|WP_011610968.1|1919536_1919836_-|heat-shock-70kD-protein-12B	gnl|CDD|212671	cd10229, HSPA12_like_NBD, Nucleotide-binding domain of HSPA12A, HSPA12B and similar proteins. Human HSPA12A (also known as 70-kDa heat shock protein-12A) and HSPA12B (also known as 70-kDa heat shock protein-12B, chromosome 20 open reading frame 60/C20orf60, dJ1009E24.2) belong to the heat shock protein 70 (HSP70) family of chaperones that assist in protein folding and assembly, and can direct incompetent "client" proteins towards degradation. Typically, HSP70s have a nucleotide-binding domain (NBD) and a substrate-binding domain (SBD). The nucleotide sits in a deep cleft formed between the two lobes of the NBD. The two subdomains of each lobe change conformation between ATP-bound, ADP-bound, and nucleotide-free states. ATP binding opens up the substrate-binding site; substrate-binding increases the rate of ATP hydrolysis. HSP70 chaperone activity is regulated by various co-chaperones: J-domain proteins and nucleotide exchange factors (NEFs). No co-chaperones have yet been identified for HSPA12A or HSPA12B. The gene encoding HSPA12A maps to 10q26.12, a cytogenetic region that might represent a common susceptibility locus for both schizophrenia and bipolar affective disorder; reduced expression of HSPA12A has been shown in the prefrontal cortex of subjects with schizophrenia. HSPA12A is also a candidate gene for forelimb-girdle muscular anomaly, an autosomal recessive disorder of Japanese black cattle. HSPA12A is predominantly expressed in neuronal cells. It may also play a role in the atherosclerotic process. The gene encoding HSPA12B maps to 20p13. HSPA12B is predominantly expressed in endothelial cells, is required for angiogenesis, and may interact with known angiogenesis mediators. It may be important for host defense in microglia-mediated immune response. HSPA12B expression is up-regulated in lipopolysaccharide (LPS)-induced inflammatory response in the spinal cord, and mostly located in active microglia; this induced expression may be regulated by activation of MAPK-p38, ERK1/2 and SAPK/JNK signaling pathways. Overexpression of HSPA12B also protects against LPS-induced cardiac dysfunction and involves the preserved activation of the PI3K/Akt signaling pathway.	1.26952e-19
NC_008312.1|WP_081432408.1|1951618_1951768_+|hypothetical-protein	gnl|CDD|279973	pfam01710, HTH_Tnp_IS630, Transposase. Transposase proteins are necessary for efficient DNA transposition. This family includes insertion sequences from Synechocystis PCC 6803 three of which are characterized as homologous to bacterial IS5- and IS4- and to several members of the IS630-Tc1-mariner superfamily.	3.34977e-06
NC_008312.1|WP_011610974.1|1934395_1935022_+|DnaJ-domain-containing-protein	gnl|CDD|223560	COG0484, DnaJ, DnaJ-class molecular chaperone with C-terminal Zn finger domain [Posttranslational modification, protein turnover, chaperones].	6.45829e-16
NC_008312.1|WP_011610963.1|1908789_1910424_+|HD-domain-containing-protein	gnl|CDD|225116	COG2206, COG2206, c-di-GMP phosphodiesterase class II (HD-GYP domain) [Signal transduction mechanisms].	1.16593e-26
NC_008312.1|WP_011610967.1|1917667_1919488_-|Hsp70-family-protein	gnl|CDD|212671	cd10229, HSPA12_like_NBD, Nucleotide-binding domain of HSPA12A, HSPA12B and similar proteins. Human HSPA12A (also known as 70-kDa heat shock protein-12A) and HSPA12B (also known as 70-kDa heat shock protein-12B, chromosome 20 open reading frame 60/C20orf60, dJ1009E24.2) belong to the heat shock protein 70 (HSP70) family of chaperones that assist in protein folding and assembly, and can direct incompetent "client" proteins towards degradation. Typically, HSP70s have a nucleotide-binding domain (NBD) and a substrate-binding domain (SBD). The nucleotide sits in a deep cleft formed between the two lobes of the NBD. The two subdomains of each lobe change conformation between ATP-bound, ADP-bound, and nucleotide-free states. ATP binding opens up the substrate-binding site; substrate-binding increases the rate of ATP hydrolysis. HSP70 chaperone activity is regulated by various co-chaperones: J-domain proteins and nucleotide exchange factors (NEFs). No co-chaperones have yet been identified for HSPA12A or HSPA12B. The gene encoding HSPA12A maps to 10q26.12, a cytogenetic region that might represent a common susceptibility locus for both schizophrenia and bipolar affective disorder; reduced expression of HSPA12A has been shown in the prefrontal cortex of subjects with schizophrenia. HSPA12A is also a candidate gene for forelimb-girdle muscular anomaly, an autosomal recessive disorder of Japanese black cattle. HSPA12A is predominantly expressed in neuronal cells. It may also play a role in the atherosclerotic process. The gene encoding HSPA12B maps to 20p13. HSPA12B is predominantly expressed in endothelial cells, is required for angiogenesis, and may interact with known angiogenesis mediators. It may be important for host defense in microglia-mediated immune response. HSPA12B expression is up-regulated in lipopolysaccharide (LPS)-induced inflammatory response in the spinal cord, and mostly located in active microglia; this induced expression may be regulated by activation of MAPK-p38, ERK1/2 and SAPK/JNK signaling pathways. Overexpression of HSPA12B also protects against LPS-induced cardiac dysfunction and involves the preserved activation of the PI3K/Akt signaling pathway.	3.42148e-57
NC_008312.1|WP_011610969.1|1919853_1921656_-|hypothetical-protein	gnl|CDD|130902	TIGR01843, Hemolysin_secretion_protein_D_plasmid, type I secretion membrane fusion protein, HlyD family. Type I secretion is an ABC transport process that exports proteins, without cleavage of any signal sequence, from the cytosol to extracellular medium across both inner and outer membranes. The secretion signal is found in the C-terminus of the transported protein. This model represents the adaptor protein between the ATP-binding cassette (ABC) protein of the inner membrane and the outer membrane protein, and is called the membrane fusion protein. This model selects a subfamily closely related to HlyD; it is defined narrowly and excludes, for example, colicin V secretion protein CvaA and multidrug efflux proteins. [Protein fate, Protein and peptide secretion and trafficking].	0.00701294
NC_008312.1|WP_011610973.1|1930922_1931513_+|ATP-dependent-Clp-endopeptidase-proteolytic-subunit-ClpP	gnl|CDD|178955	PRK00277, clpP, ATP-dependent Clp protease proteolytic subunit; Reviewed.	9.14803e-137
NC_008312.1|WP_011610970.1|1922202_1922877_+|J-domain-containing-protein	gnl|CDD|223560	COG0484, DnaJ, DnaJ-class molecular chaperone with C-terminal Zn finger domain [Posttranslational modification, protein turnover, chaperones].	1.17271e-25
NC_008312.1|WP_011610976.1|1938099_1939044_+|calcium/sodium-antiporter	gnl|CDD|223604	COG0530, ECM27, Ca2+/Na+ antiporter [Inorganic ion transport and metabolism].	1.30101e-56
NC_008312.1|WP_044136478.1|1942928_1943162_+|winged-helix-turn-helix-domain-containing-protein	gnl|CDD|379282	pfam13592, HTH_33, Winged helix-turn helix. This helix-turn-helix domain is often found in transferases and is likely to be DNA-binding.	8.17753e-06
NC_008312.1|WP_011610986.1|1954985_1955288_+|helix-turn-helix-domain-containing-protein	gnl|CDD|379256	pfam13551, HTH_29, Winged helix-turn helix. This helix-turn-helix domain is often found in transferases and is likely to be DNA-binding.	5.28078e-07
NC_008312.1|WP_011610979.1|1944501_1944867_-|phage-holin-family-protein	gnl|CDD|224861	COG1950, COG1950, Predicted membrane protein [Function unknown].	2.7918e-18
NC_008312.1|WP_011610975.1|1935766_1937014_+|FkbM-family-methyltransferase	gnl|CDD|273628	TIGR01444, 2-O-methyltransferase_NoeI, methyltransferase, FkbM family. Members of this family are characterized by two well-conserved short regions separated by a variable in both sequence and length. The first of the two regions is found in a large number of proteins outside this subfamily, a number of which have been characterized as methyltransferases. One member of the present family, FkbM, was shown to be required for a specific methylation in the biosynthesis of the immunosuppressant FK506 in Streptomyces strain MA6548.	2.51244e-24
NC_008312.1|WP_011610962.1|1907659_1907941_+|4a-hydroxytetrahydrobiopterin-dehydratase	gnl|CDD|234845	PRK00823, phhB, pterin-4-alpha-carbinolamine dehydratase; Validated.	9.07031e-38
NC_008312.1|WP_011610964.1|1911567_1913487_+|iron-uptake-porin	gnl|CDD|335962	pfam04966, OprB, Carbohydrate-selective porin, OprB family.	1.16142e-31
NC_008312.1|WP_011610965.1|1914920_1915883_+|cysteine-synthase-A	gnl|CDD|273465	TIGR01139, Cysteine_synthase, cysteine synthase A. This model distinguishes cysteine synthase A (CysK) from cysteine synthase B (CysM). CysM differs in having a broader specificity that also allows the use of thiosulfate to produce cysteine thiosulfonate. [Amino acid biosynthesis, Serine family].	4.76052e-173
NC_008312.1|WP_011610980.1|1944893_1945985_-|redox-regulated-ATPase-YchF	gnl|CDD|236583	PRK09601, PRK09601, redox-regulated ATPase YchF.	0
NC_008312.1|WP_011610971.1|1926210_1927449_-|VWA-domain-containing-protein	gnl|CDD|225187	COG2304, COG2304, Uncharacterized protein containing a von Willebrand factor type A (vWA) domain [General function prediction only].	7.63218e-61

Protein sequences

>NC_008312.1|WP_011610971.1|1926210_1927449_-|VWA-domain-containing-protein
MKVNLRSALNDTNIDASQSLSQRQVALSISVMANQLERTVPLNLCLILDHSGSMEGRPLETVKQAAVQLVEKLKEGDRLSVVAFDHQAQVIVPNQMINDSASIKGKINKLRASGGTAIDKGLKLGIEELNKGRKESISQAFILTDGENEHGDNDLCLKLAKLATDYNITLNSLGFGDDWNQDVLEKIADAGGGNLSYIQQPEQAIEEFSKLFNRIKSVGITNSYLQFYLMPKVRLAELKPIAQVAPDTIELPVKKEGNGFIVRLGDLMKDIERVVLVNTYIGQLPEGKQAIAQLQIRYDDPAQNQEGLLSESILVEANFMEKYQPQVNSQVQNHILALAKYRQTQIAETKLQQGDRAGAATMLQTAAKTALQMGDTGAATVLQTSATRLQDGDKLSEMERKKTRIVSKTILK
>NC_008312.1|WP_011610970.1|1922202_1922877_+|J-domain-containing-protein
MVSSDYYKILNVHPTATQGQIRQAYRRLVKLFHPDTNTEVANHERIISINEAYEVLSDPQQRKSYDQQLNQNYQRYRNISQDYYKHNKRRQNIDEHLQRWINHVYRPVDTIIIQILKPLKNEIDDLAADPFDDQLLESFQDYLETSRGLLKKAHNLFSSQPNPSNFAGVAAHLYYCLNQVSDGIEDLELFTLNYDDYYLHTGQELFRIADKLRQEAQAAIKGIF
>NC_008312.1|WP_011610969.1|1919853_1921656_-|hypothetical-protein
MEKFLPNKKNWFQHLAEGFSDFFWGTRSARMSSETLRINNDNLIEYYEKRDSIQQQIQIAQIQLKTVMEERNFQFQYEQGNLNRQFQAQQGELNRQLQTELGTINRLFQAEEGKLNRELQTELARLNREHQIQEGKLNRENAHQLELFRAQLQIFLQEKQKDLQLQLKEIDATLARELKAIDLQNNLTVIRQQRRLNNWPLTLDDEQIKEIVKSDNLLILFVPPILKYDRAGAGANSQPNTFPDIEQGLNRRLRAFLEKYKQTGRKVDFLTGAWMTKALSGEGAFKTIFSGLKSKPMLVINTLVERTYYHLEYSYWSQNFPEPYIDSLPKEDPLSWLELLYFAVKERLLKWEKQRNQEKIETGTTEEFDADWGEEVVKKFLADLQLIKREKRLLERGQDPNNLPNRNYTVLDSDKETFSRFIAIQVSLLIGRTADAYFLLDVPPQERKRPLLPELLPNLLEEIPSEEREKIIEYLVYFYQSLYQQLGEEESAWVPEMLIDFASSLIYLDNKFWAKEQIEKSVESWLLMRGIKSLDQVSNLEVMKYVLVSGDDEYLDRLNQFILLLGRENYVIIAETLLDTWRKLKIKGCIGVDGHGQTLF
>NC_008312.1|WP_011610968.1|1919536_1919836_-|heat-shock-70kD-protein-12B
MDKSFEVVVAIDFGTSRSGFAYKFKESDVSVFRDLWPDNPMSYPKTATYLLLSSTGEVEAWGYTAMKKLAQFRAQGTAKDYYFTRNFKMELHSGKKDES
>NC_008312.1|WP_011610967.1|1917667_1919488_-|Hsp70-family-protein
MIAKYIRLIKDEALKEIKNSTSGELKDQEIRWCLSIPAIWKNEDKDLMRRAARKAGLINSSDDEAERLFLVLEPEAAAIFCQEEDKNALTPGNKIMIIDCGGGTVDITVHKLVKDGGLDEVAPGTGGPFGSIYVDKSFQEYLTEKLSAEMVKGFHDQDPVGYLKMMEEWERTKCNFDPETSGDVIYFNIPTRLYNFISKRKAKILEQLADEQNGDDENIHLSYSTMENIFRITVHKLVKDGGLDEVAPGTGGPFGSIYVDKSFQEYLTEKLSAEMVKGFHDQEPVDYLKMMEEWERTKCNFDPETSGDVIYFNIPTRLYNFISKRKAKILEQLADEQNGDDKNIHLSYSTMENIFRPTLDGLVSTVKNQFKELGDEEVDIIFLVGGFSTSPVLRQRIKKEFGSKAKKIVMPPRPGVAILKGAASFGVAPGIIRARRSRLTYGVSSSREFNQFKDTIISQKQQSDNPENWENCLRVYKNNNDFLNWLLNNFDIQYSNHNHEQEKQQINSLKNALKNPKKLLEKFYNIYLMIVEPKKRYNQKHKQELKETVYLLNQKIQSQEILINELKRENEKLRKLKSSLLSKLSDRDRDTSNTITSDESRPQRDV
>NC_008312.1|WP_011610966.1|1916944_1917445_-|hypothetical-protein
MKNSILTDLQIPEAAKFPEPIPTNLKNLVEKGLKLVKEIVNDDPPGHFLIANPGEIFNPENHEPVPSCEPSGQIVYTTYPGYSVNNRIIGESLKAFVFTEPNKQPEGQEEQPFENNQNHQQPNSIENEQQSPSNQQLKPTSNHQSPVPQTSENNQNNQQPSSIENQ
>NC_008312.1|WP_011610965.1|1914920_1915883_+|cysteine-synthase-A
MRIAHNITELVGRTPLVQLNSIPKAEGCLAKIIVKLEGMNPAASVKDRIGVNMINVAEREGLIKPGKTTLVEPTSGNTGIALAMVAAARGYKLILTMPETMSMERRVMLRAYGAELVLTPGSEGMKGAITKAQEIVDLSSNGYYMLQQFQNPANPEIHSKTTALEIWEDTDGKVDILVAGVGTGGTVTGVAETIKARKPEFQAIAVEPSNSPVLSGGKPGPHKIQGIGAGFVPDVLDTKIIDEVIQVPDSEAMVYGRRIAKEEGILSGISTGAALCAAIEVGKRPENDGKLIVMIQPSFGERYLSTPLFQELGPTLAEVR
>NC_008312.1|WP_011610964.1|1911567_1913487_+|iron-uptake-porin
MSKTFWYCLILSPAVLGATLVASSYALATENKQTNTVIQPQAATTENISINNNIDIQEPDLLAQVTATNSTNSVGNTPATTIRQINRYGREGRNLRRPGLRNITNNRKPIKGQVTSVSQLSDVQPTDWAFQALQSLVERYGCIVGYPDGTYRGNRALTRFEFAAGVNACLDRVMELLQAAIEDTVSREDLAILQRLQEEFSAELAILRGRVDALEARAAELEANQFSTTTKLRGEVIFALVDNFEDQGKYGAFGDTIQDEDQTVFQYRVRLNFNTSFSGEDLLFTRLQAGNAQAFNQKIAESEGQQTFNILDRTDDTLQLDKLFYKFPVRDNIRVTIAANKVSWYDFVPTLNPYMEDFDGGSGSLSAFGQRNPIYRLGGGKGLGVEYDFGCKDQYACTYSPFSVSFGYLAAEGENPSQGKGLFNGDYAALAQLTFTPIRNFQVGLTYNKGYFGPGNFGFDDGAATGLGDNGSLNSGFVGTGIANSVYGLNAGLNDRRPGSVNINKSVSTNAYGVEMSWRAADWVTINGFGTYLDGKLIGKGDFEIWTYGATIAFPDLLKEGSLAGIVVGREPYLNDLELPSGLDSGLRQDMSWHLEAFYKYQLTDYISITPGVTVITNANQDDDNDELIIGTIRTTFQF
>NC_008312.1|WP_011610963.1|1908789_1910424_+|HD-domain-containing-protein
MIQLNTLKLFQELTETSELLIIEQLLDIGVALSDTYNLGELLNLILSKSREITCSDAGSVYLVDEVNFKERKLVFKVAQNDSIPELAFQEIALPIDFKSLTGYVALTGHTLNIPDAYNLPKDIPYKFDESFDEKTGYRTCSVLILPVQKQNQEIIGVLQLINRKVQPDVVITKENAKELTKAYSKWEQRILISLASQAAISIERNNLQENIENLFEGFVKASVQAIEARDSCTSGHSERVAKLTVGLCQEVNIITNGVFSGTYFSNEQIQEMRYAALLHDFGKIGVPEGILTKRKKLYQEQLELIKQRFSVAQRTLEMESAQTKYEYLLRHLSGTYQSHTQESCPLCQKIENLDLELKTAITQLNNYWQTILIANEPKVLAEEPLKQLQQISLYTYKDTDGQIKPLITSEEMAQLTVPRGNLTPEERRAVEAHVTHSYEFLKQIAWTKNLQNIPEIAYGHHEKLDGSGYPRGLKKNEISLQTQIIVIADIYDALTAGDRPYKQGLPVEAALRIMRSEAAENKINSHFLELFEQKQVFSILGHSK
>NC_008312.1|WP_011610962.1|1907659_1907941_+|4a-hydroxytetrahydrobiopterin-dehydratase
MTELLAVEEINQRISQISDWKLEGNKLKYIKTVKNFVEAINFVNKLVAPAEASQHHPDLEVSYNKVTIILTTHNSGGLTEKDFKMAKTISGLS
>NC_008312.1|WP_011610973.1|1930922_1931513_+|ATP-dependent-Clp-endopeptidase-proteolytic-subunit-ClpP
MPIGIPSVPYRLPGSQYERWIDIYTRLGQERIIFLGQEVTDGLANRIVAYMLYLDSDDPNKPIYLYINSPGGSVTAGLAIYDTMQYIKADVITICLGLAASMGSFLLAAGTKGKRLALPNSRIMIHQPMGGTRGQATDIEIEANEILRVRSELNNMLAERTGQSLEKIEKDTDRDYYMSAEEAKEYGLIDQVIEER
>NC_008312.1|WP_011610974.1|1934395_1935022_+|DnaJ-domain-containing-protein
MNIADYYRKLDLNLGASLGEVKASYRRLARMYHPDVNPKDKHAKDKFIAVTEAYKILLRVAPAQAELPYNLTPTSTTNKNSKSETVSPRETKVRRTVKQKQNQNKSHTLEVERQLKQNYYLQLKHLLKYKRYPRAIALAEGLAQRMPQDPEVRQWQAIAYQRWGRQLINERKLDKARNYLKKALKTDPQNRDLWAEIEYDFHQLEKIY
>NC_008312.1|WP_011610975.1|1935766_1937014_+|FkbM-family-methyltransferase
MTDINQEFQRALKFQKEGKLQEAESIYINILKSDSDHVASLINLGLIEQSQGKLEEATQFYKYAFQIDSNNISLLYLLARITQELNQLDEAINYWQKLVQLKPDGTLEFYGNIGNSLVQQGKFDEALNCFRDALKISPNSFQAHQAIGNLLIRKEQLLEAKLEFSKALEINPNYQTAKIWLTLVDKLLKGENIVSFNYQSTPIKFEITGKNLAVEIANVGGTFYELPELEFIRQNLKSSNPVIVDIGANTGNHLVYFAKIMQASKVIPIEFHPDILATLKKHISINQVSNIDLSILGYAIGENSGTSFIKEHPAKDLCLTEIDNNIINGTKVEVMTLDDLIKEKVDFIKVDVQGTEVKALTGAKNLISIYQPDMLVEVAKNHMKDFRKFLEAVKYQTVKAFDHGRYVNFYIQHTK
>NC_008312.1|WP_011610976.1|1938099_1939044_+|calcium/sodium-antiporter
MPNLIIWLIIFIVSLFVLIKASDFFTDAAEKIGISLGISPFLVGVTIVSIGTSLPELVSSIIAVYQNSSEIVFGNVMGSNIANIFLIIGTASLISSPLKILYELINVDLPLFVGSAFLLGLTVLDSNFSINEAIICILGYIVYVFYAISSGKEEQQSETIDTSQKSFPVKQIVILIISSLFIFFGATYTIKSVTKISEILEVGKELIALSAVALGTSLPELIVTISAARKGNPEIAVGNVLGSNIFNSLMVMGIPRLTGKLEIPDDVLDSGLLVLLVGTILFFFVTQDKQVTRWEGLIFFIFYGWFIGNIFGLV
>NC_008312.1|WP_044136478.1|1942928_1943162_+|winged-helix-turn-helix-domain-containing-protein
MILKELPRDYVVDRNIWRGKIISNVIELRWGVKLKTTRIYKILNELNLSAQKAHINYANASQEQQKTFILSLKKIGI
>NC_008312.1|WP_155994328.1|1943206_1943395_+|hypothetical-protein
MSAQVFFTDGQKKNTAPEVPSNEKGFINKLNGMISVDAFTAQEYLKLKEKSKTEEVSDDFLQ
>NC_008312.1|WP_011610979.1|1944501_1944867_-|phage-holin-family-protein
MSILQLLILWFVTAVSLFIISKLPTGVEIDDFKIALISSVVFGFLNALVRPVLVAVVFPIKIVLSSFLFTLLLNMSIFGLAAWLVSGFRLRWGFWSALIGSVALGFINSFLYELLNRVVVS
>NC_008312.1|WP_011610980.1|1944893_1945985_-|redox-regulated-ATPase-YchF
MLRAGIVGLPNVGKSTLFNALVANAKAEAANFPFCTIEPNVGVVAVPDNRLNVLAQISNSAQTVPTRIEFVDIAGLVKGASKGEGLGNQFLSNIREVDAIVQVVRCFDSEDIIHVSGSVDPVRDIEVINLELALSDLAQVERRIERTKKQARTSKEAQTELEVLEKLEVVLNEGNSVKMAGLNKDESLIIKPLNLLTSKPIIYAANVSEDDLANGNDWVEKVRNIAAVENAQVVVISAQVESELIELPEEEITDYLKSLGVEEGGLKSLIKATYELLGLHTYFTTGEKETKAWTIKAGTLAPQAAGVIHTDFERGFIRAETIAYKDLVTSGSMTTAKEKGLVRSEGKDYLVKEGDIMLFRFNV
>NC_008312.1|WP_081432408.1|1951618_1951768_+|hypothetical-protein
MTYRWSSRPKLEATKVKRRRIKLDWKELEKDVKPNLEFKLAYKAKKNWS
>NC_008312.1|WP_011610986.1|1954985_1955288_+|helix-turn-helix-domain-containing-protein
MIYCLKTNQVLTRAELAKVLGRHESTITRWLTLYRAGGLKKLLEVKNVPGKTSKISPEILAGLQAKLSETIGFNSLGEIPKWLIEKYQVQLADKTVHKIF

Crispr_ID: NC_008312_17

• CRISPR_ID: NC_008312_17
• CRISPR_location: 1941216-1941324
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NC_008312_17

Consensus_repeat	Method
ATTGAAAACTTTTGGTTAAAAGTGAAAGCTATTCTAA	CRISPRCasFinder

spacers of NC_008312_17

>17.1|1941253|35|NC_008312|CRISPRCasFinder
TAATAGTTAAAGCAAGAAATTATAAAGATTTAATT

CRISPR arrays and Neighbor proteins around NC_008312_17

CRISPR arrays

The CRISPR arrays of NC_008312_17

>merge|NC_008312|17|1941216-1941324|CRISPRCasFinder
ATTGAAAACTTTTGGTTAAAAGTGAAAGCTATTCTAATAATAGTTAAAGCAAGAAATTATAAAGATTTAATTATTGAAAACTTTTGGTTAAAAGTGAAAGCTATTCTAA

>NC_008312|17|14|1941216-1941324|CRISPRCasFinder
ATTGAAAACTTTTGGTTAAAAGTGAAAGCTATTCTAA	TAATAGTTAAAGCAAGAAATTATAAAGATTTAATT
ATTGAAAACTTTTGGTTAAAAGTGAAAGCTATTCTAA

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_008312.1|WP_011610968.1|1919536_1919836_-|heat-shock-70kD-protein-12B	unknown	unknown	gnl|CDD|212671
NC_008312.1|WP_081432408.1|1951618_1951768_+|hypothetical-protein	unknown	unknown	gnl|CDD|279973
NC_008312.1|WP_011610974.1|1934395_1935022_+|DnaJ-domain-containing-protein	unknown	unknown	gnl|CDD|223560
NC_008312.1|WP_044136478.1|1942928_1943162_+|winged-helix-turn-helix-domain-containing-protein	unknown	unknown	gnl|CDD|379282
NC_008312.1|WP_044136482.1|1956797_1957007_+|hypothetical-protein	unknown	unknown	gnl|CDD|379284
NC_008312.1|WP_155994329.1|1955349_1955784_+|hypothetical-protein	unknown	unknown	gnl|CDD|315923
NC_008312.1|WP_011610967.1|1917667_1919488_-|Hsp70-family-protein	unknown	unknown	gnl|CDD|212671
NC_008312.1|WP_011610969.1|1919853_1921656_-|hypothetical-protein	unknown	unknown	gnl|CDD|130902
NC_008312.1|WP_011610972.1|1930018_1930708_+|ATP-dependent-Clp-protease-proteolytic-subunit	unknown	unknown	gnl|CDD|183588
NC_008312.1|WP_155994331.1|1956045_1956186_-|hypothetical-protein	unknown	unknown	gnl|CDD|225949
NC_008312.1|WP_011610973.1|1930922_1931513_+|ATP-dependent-Clp-endopeptidase-proteolytic-subunit-ClpP	unknown	unknown	gnl|CDD|178955
NC_008312.1|WP_155994328.1|1943206_1943395_+|hypothetical-protein	unknown	unknown	unknown
NC_008312.1|WP_011610976.1|1938099_1939044_+|calcium/sodium-antiporter	unknown	unknown	gnl|CDD|223604
NC_008312.1|WP_011610986.1|1954985_1955288_+|helix-turn-helix-domain-containing-protein	unknown	unknown	gnl|CDD|379256
NC_008312.1|WP_155994330.1|1955777_1955945_+|hypothetical-protein	unknown	unknown	unknown
NC_008312.1|WP_011610979.1|1944501_1944867_-|phage-holin-family-protein	unknown	unknown	gnl|CDD|224861
NC_008312.1|WP_011610975.1|1935766_1937014_+|FkbM-family-methyltransferase	unknown	unknown	gnl|CDD|273628
NC_008312.1|WP_011610970.1|1922202_1922877_+|J-domain-containing-protein	unknown	unknown	gnl|CDD|223560
NC_008312.1|WP_011610980.1|1944893_1945985_-|redox-regulated-ATPase-YchF	unknown	unknown	gnl|CDD|236583
NC_008312.1|WP_011610971.1|1926210_1927449_-|VWA-domain-containing-protein	unknown	unknown	gnl|CDD|225187

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_008312.1|WP_011610968.1|1919536_1919836_-|heat-shock-70kD-protein-12B	gnl|CDD|212671	cd10229, HSPA12_like_NBD, Nucleotide-binding domain of HSPA12A, HSPA12B and similar proteins. Human HSPA12A (also known as 70-kDa heat shock protein-12A) and HSPA12B (also known as 70-kDa heat shock protein-12B, chromosome 20 open reading frame 60/C20orf60, dJ1009E24.2) belong to the heat shock protein 70 (HSP70) family of chaperones that assist in protein folding and assembly, and can direct incompetent "client" proteins towards degradation. Typically, HSP70s have a nucleotide-binding domain (NBD) and a substrate-binding domain (SBD). The nucleotide sits in a deep cleft formed between the two lobes of the NBD. The two subdomains of each lobe change conformation between ATP-bound, ADP-bound, and nucleotide-free states. ATP binding opens up the substrate-binding site; substrate-binding increases the rate of ATP hydrolysis. HSP70 chaperone activity is regulated by various co-chaperones: J-domain proteins and nucleotide exchange factors (NEFs). No co-chaperones have yet been identified for HSPA12A or HSPA12B. The gene encoding HSPA12A maps to 10q26.12, a cytogenetic region that might represent a common susceptibility locus for both schizophrenia and bipolar affective disorder; reduced expression of HSPA12A has been shown in the prefrontal cortex of subjects with schizophrenia. HSPA12A is also a candidate gene for forelimb-girdle muscular anomaly, an autosomal recessive disorder of Japanese black cattle. HSPA12A is predominantly expressed in neuronal cells. It may also play a role in the atherosclerotic process. The gene encoding HSPA12B maps to 20p13. HSPA12B is predominantly expressed in endothelial cells, is required for angiogenesis, and may interact with known angiogenesis mediators. It may be important for host defense in microglia-mediated immune response. HSPA12B expression is up-regulated in lipopolysaccharide (LPS)-induced inflammatory response in the spinal cord, and mostly located in active microglia; this induced expression may be regulated by activation of MAPK-p38, ERK1/2 and SAPK/JNK signaling pathways. Overexpression of HSPA12B also protects against LPS-induced cardiac dysfunction and involves the preserved activation of the PI3K/Akt signaling pathway.	1.26952e-19
NC_008312.1|WP_081432408.1|1951618_1951768_+|hypothetical-protein	gnl|CDD|279973	pfam01710, HTH_Tnp_IS630, Transposase. Transposase proteins are necessary for efficient DNA transposition. This family includes insertion sequences from Synechocystis PCC 6803 three of which are characterized as homologous to bacterial IS5- and IS4- and to several members of the IS630-Tc1-mariner superfamily.	3.34977e-06
NC_008312.1|WP_011610974.1|1934395_1935022_+|DnaJ-domain-containing-protein	gnl|CDD|223560	COG0484, DnaJ, DnaJ-class molecular chaperone with C-terminal Zn finger domain [Posttranslational modification, protein turnover, chaperones].	6.45829e-16
NC_008312.1|WP_044136478.1|1942928_1943162_+|winged-helix-turn-helix-domain-containing-protein	gnl|CDD|379282	pfam13592, HTH_33, Winged helix-turn helix. This helix-turn-helix domain is often found in transferases and is likely to be DNA-binding.	8.17753e-06
NC_008312.1|WP_044136482.1|1956797_1957007_+|hypothetical-protein	gnl|CDD|379284	pfam13597, NRDD, Anaerobic ribonucleoside-triphosphate reductase.	0.00152321
NC_008312.1|WP_155994329.1|1955349_1955784_+|hypothetical-protein	gnl|CDD|315923	pfam13358, DDE_3, DDE superfamily endonuclease. This family of proteins are related to pfam00665 and are probably endonucleases of the DDE superfamily. Transposase proteins are necessary for efficient DNA transposition. This domain is a member of the DDE superfamily, which contain three carboxylate residues that are believed to be responsible for coordinating metal ions needed for catalysis. The catalytic activity of this enzyme involves DNA cleavage at a specific site followed by a strand transfer reaction.	4.11044e-10
NC_008312.1|WP_011610967.1|1917667_1919488_-|Hsp70-family-protein	gnl|CDD|212671	cd10229, HSPA12_like_NBD, Nucleotide-binding domain of HSPA12A, HSPA12B and similar proteins. Human HSPA12A (also known as 70-kDa heat shock protein-12A) and HSPA12B (also known as 70-kDa heat shock protein-12B, chromosome 20 open reading frame 60/C20orf60, dJ1009E24.2) belong to the heat shock protein 70 (HSP70) family of chaperones that assist in protein folding and assembly, and can direct incompetent "client" proteins towards degradation. Typically, HSP70s have a nucleotide-binding domain (NBD) and a substrate-binding domain (SBD). The nucleotide sits in a deep cleft formed between the two lobes of the NBD. The two subdomains of each lobe change conformation between ATP-bound, ADP-bound, and nucleotide-free states. ATP binding opens up the substrate-binding site; substrate-binding increases the rate of ATP hydrolysis. HSP70 chaperone activity is regulated by various co-chaperones: J-domain proteins and nucleotide exchange factors (NEFs). No co-chaperones have yet been identified for HSPA12A or HSPA12B. The gene encoding HSPA12A maps to 10q26.12, a cytogenetic region that might represent a common susceptibility locus for both schizophrenia and bipolar affective disorder; reduced expression of HSPA12A has been shown in the prefrontal cortex of subjects with schizophrenia. HSPA12A is also a candidate gene for forelimb-girdle muscular anomaly, an autosomal recessive disorder of Japanese black cattle. HSPA12A is predominantly expressed in neuronal cells. It may also play a role in the atherosclerotic process. The gene encoding HSPA12B maps to 20p13. HSPA12B is predominantly expressed in endothelial cells, is required for angiogenesis, and may interact with known angiogenesis mediators. It may be important for host defense in microglia-mediated immune response. HSPA12B expression is up-regulated in lipopolysaccharide (LPS)-induced inflammatory response in the spinal cord, and mostly located in active microglia; this induced expression may be regulated by activation of MAPK-p38, ERK1/2 and SAPK/JNK signaling pathways. Overexpression of HSPA12B also protects against LPS-induced cardiac dysfunction and involves the preserved activation of the PI3K/Akt signaling pathway.	3.42148e-57
NC_008312.1|WP_011610969.1|1919853_1921656_-|hypothetical-protein	gnl|CDD|130902	TIGR01843, Hemolysin_secretion_protein_D_plasmid, type I secretion membrane fusion protein, HlyD family. Type I secretion is an ABC transport process that exports proteins, without cleavage of any signal sequence, from the cytosol to extracellular medium across both inner and outer membranes. The secretion signal is found in the C-terminus of the transported protein. This model represents the adaptor protein between the ATP-binding cassette (ABC) protein of the inner membrane and the outer membrane protein, and is called the membrane fusion protein. This model selects a subfamily closely related to HlyD; it is defined narrowly and excludes, for example, colicin V secretion protein CvaA and multidrug efflux proteins. [Protein fate, Protein and peptide secretion and trafficking].	0.00701294
NC_008312.1|WP_011610972.1|1930018_1930708_+|ATP-dependent-Clp-protease-proteolytic-subunit	gnl|CDD|183588	PRK12552, PRK12552, ATP-dependent Clp protease proteolytic subunit.	8.42013e-163
NC_008312.1|WP_155994331.1|1956045_1956186_-|hypothetical-protein	gnl|CDD|225949	COG3415, COG3415, Transposase and inactivated derivatives [DNA replication, recombination, and repair].	0.000228119
NC_008312.1|WP_011610973.1|1930922_1931513_+|ATP-dependent-Clp-endopeptidase-proteolytic-subunit-ClpP	gnl|CDD|178955	PRK00277, clpP, ATP-dependent Clp protease proteolytic subunit; Reviewed.	9.14803e-137
NC_008312.1|WP_011610976.1|1938099_1939044_+|calcium/sodium-antiporter	gnl|CDD|223604	COG0530, ECM27, Ca2+/Na+ antiporter [Inorganic ion transport and metabolism].	1.30101e-56
NC_008312.1|WP_011610986.1|1954985_1955288_+|helix-turn-helix-domain-containing-protein	gnl|CDD|379256	pfam13551, HTH_29, Winged helix-turn helix. This helix-turn-helix domain is often found in transferases and is likely to be DNA-binding.	5.28078e-07
NC_008312.1|WP_011610979.1|1944501_1944867_-|phage-holin-family-protein	gnl|CDD|224861	COG1950, COG1950, Predicted membrane protein [Function unknown].	2.7918e-18
NC_008312.1|WP_011610975.1|1935766_1937014_+|FkbM-family-methyltransferase	gnl|CDD|273628	TIGR01444, 2-O-methyltransferase_NoeI, methyltransferase, FkbM family. Members of this family are characterized by two well-conserved short regions separated by a variable in both sequence and length. The first of the two regions is found in a large number of proteins outside this subfamily, a number of which have been characterized as methyltransferases. One member of the present family, FkbM, was shown to be required for a specific methylation in the biosynthesis of the immunosuppressant FK506 in Streptomyces strain MA6548.	2.51244e-24
NC_008312.1|WP_011610970.1|1922202_1922877_+|J-domain-containing-protein	gnl|CDD|223560	COG0484, DnaJ, DnaJ-class molecular chaperone with C-terminal Zn finger domain [Posttranslational modification, protein turnover, chaperones].	1.17271e-25
NC_008312.1|WP_011610980.1|1944893_1945985_-|redox-regulated-ATPase-YchF	gnl|CDD|236583	PRK09601, PRK09601, redox-regulated ATPase YchF.	0
NC_008312.1|WP_011610971.1|1926210_1927449_-|VWA-domain-containing-protein	gnl|CDD|225187	COG2304, COG2304, Uncharacterized protein containing a von Willebrand factor type A (vWA) domain [General function prediction only].	7.63218e-61

Protein sequences

>NC_008312.1|WP_011610976.1|1938099_1939044_+|calcium/sodium-antiporter
MPNLIIWLIIFIVSLFVLIKASDFFTDAAEKIGISLGISPFLVGVTIVSIGTSLPELVSSIIAVYQNSSEIVFGNVMGSNIANIFLIIGTASLISSPLKILYELINVDLPLFVGSAFLLGLTVLDSNFSINEAIICILGYIVYVFYAISSGKEEQQSETIDTSQKSFPVKQIVILIISSLFIFFGATYTIKSVTKISEILEVGKELIALSAVALGTSLPELIVTISAARKGNPEIAVGNVLGSNIFNSLMVMGIPRLTGKLEIPDDVLDSGLLVLLVGTILFFFVTQDKQVTRWEGLIFFIFYGWFIGNIFGLV
>NC_008312.1|WP_011610975.1|1935766_1937014_+|FkbM-family-methyltransferase
MTDINQEFQRALKFQKEGKLQEAESIYINILKSDSDHVASLINLGLIEQSQGKLEEATQFYKYAFQIDSNNISLLYLLARITQELNQLDEAINYWQKLVQLKPDGTLEFYGNIGNSLVQQGKFDEALNCFRDALKISPNSFQAHQAIGNLLIRKEQLLEAKLEFSKALEINPNYQTAKIWLTLVDKLLKGENIVSFNYQSTPIKFEITGKNLAVEIANVGGTFYELPELEFIRQNLKSSNPVIVDIGANTGNHLVYFAKIMQASKVIPIEFHPDILATLKKHISINQVSNIDLSILGYAIGENSGTSFIKEHPAKDLCLTEIDNNIINGTKVEVMTLDDLIKEKVDFIKVDVQGTEVKALTGAKNLISIYQPDMLVEVAKNHMKDFRKFLEAVKYQTVKAFDHGRYVNFYIQHTK
>NC_008312.1|WP_011610974.1|1934395_1935022_+|DnaJ-domain-containing-protein
MNIADYYRKLDLNLGASLGEVKASYRRLARMYHPDVNPKDKHAKDKFIAVTEAYKILLRVAPAQAELPYNLTPTSTTNKNSKSETVSPRETKVRRTVKQKQNQNKSHTLEVERQLKQNYYLQLKHLLKYKRYPRAIALAEGLAQRMPQDPEVRQWQAIAYQRWGRQLINERKLDKARNYLKKALKTDPQNRDLWAEIEYDFHQLEKIY
>NC_008312.1|WP_011610973.1|1930922_1931513_+|ATP-dependent-Clp-endopeptidase-proteolytic-subunit-ClpP
MPIGIPSVPYRLPGSQYERWIDIYTRLGQERIIFLGQEVTDGLANRIVAYMLYLDSDDPNKPIYLYINSPGGSVTAGLAIYDTMQYIKADVITICLGLAASMGSFLLAAGTKGKRLALPNSRIMIHQPMGGTRGQATDIEIEANEILRVRSELNNMLAERTGQSLEKIEKDTDRDYYMSAEEAKEYGLIDQVIEER
>NC_008312.1|WP_011610972.1|1930018_1930708_+|ATP-dependent-Clp-protease-proteolytic-subunit
MKSPIKAVQTSSYYGDVSFRTPPPDLESLMLKERIVYLGLPLFSSDEVKRNVGIDVTQLIIAQLLYLQFDNPEKPIYFYINSTGTSWYTGDAIGFETEAFAICDTMSYVKPPIHTICIGQAMGTAAMILSAGTKGYRASLPHATIVLNQAKTGARGQATDISIRAKEVLVNKTTFLDILSKNTGQSVEKIAKDTDRMLYMTPEIAKEYGLIDQVLASRKELPKPLPANV
>NC_008312.1|WP_011610971.1|1926210_1927449_-|VWA-domain-containing-protein
MKVNLRSALNDTNIDASQSLSQRQVALSISVMANQLERTVPLNLCLILDHSGSMEGRPLETVKQAAVQLVEKLKEGDRLSVVAFDHQAQVIVPNQMINDSASIKGKINKLRASGGTAIDKGLKLGIEELNKGRKESISQAFILTDGENEHGDNDLCLKLAKLATDYNITLNSLGFGDDWNQDVLEKIADAGGGNLSYIQQPEQAIEEFSKLFNRIKSVGITNSYLQFYLMPKVRLAELKPIAQVAPDTIELPVKKEGNGFIVRLGDLMKDIERVVLVNTYIGQLPEGKQAIAQLQIRYDDPAQNQEGLLSESILVEANFMEKYQPQVNSQVQNHILALAKYRQTQIAETKLQQGDRAGAATMLQTAAKTALQMGDTGAATVLQTSATRLQDGDKLSEMERKKTRIVSKTILK
>NC_008312.1|WP_011610970.1|1922202_1922877_+|J-domain-containing-protein
MVSSDYYKILNVHPTATQGQIRQAYRRLVKLFHPDTNTEVANHERIISINEAYEVLSDPQQRKSYDQQLNQNYQRYRNISQDYYKHNKRRQNIDEHLQRWINHVYRPVDTIIIQILKPLKNEIDDLAADPFDDQLLESFQDYLETSRGLLKKAHNLFSSQPNPSNFAGVAAHLYYCLNQVSDGIEDLELFTLNYDDYYLHTGQELFRIADKLRQEAQAAIKGIF
>NC_008312.1|WP_011610969.1|1919853_1921656_-|hypothetical-protein
MEKFLPNKKNWFQHLAEGFSDFFWGTRSARMSSETLRINNDNLIEYYEKRDSIQQQIQIAQIQLKTVMEERNFQFQYEQGNLNRQFQAQQGELNRQLQTELGTINRLFQAEEGKLNRELQTELARLNREHQIQEGKLNRENAHQLELFRAQLQIFLQEKQKDLQLQLKEIDATLARELKAIDLQNNLTVIRQQRRLNNWPLTLDDEQIKEIVKSDNLLILFVPPILKYDRAGAGANSQPNTFPDIEQGLNRRLRAFLEKYKQTGRKVDFLTGAWMTKALSGEGAFKTIFSGLKSKPMLVINTLVERTYYHLEYSYWSQNFPEPYIDSLPKEDPLSWLELLYFAVKERLLKWEKQRNQEKIETGTTEEFDADWGEEVVKKFLADLQLIKREKRLLERGQDPNNLPNRNYTVLDSDKETFSRFIAIQVSLLIGRTADAYFLLDVPPQERKRPLLPELLPNLLEEIPSEEREKIIEYLVYFYQSLYQQLGEEESAWVPEMLIDFASSLIYLDNKFWAKEQIEKSVESWLLMRGIKSLDQVSNLEVMKYVLVSGDDEYLDRLNQFILLLGRENYVIIAETLLDTWRKLKIKGCIGVDGHGQTLF
>NC_008312.1|WP_011610968.1|1919536_1919836_-|heat-shock-70kD-protein-12B
MDKSFEVVVAIDFGTSRSGFAYKFKESDVSVFRDLWPDNPMSYPKTATYLLLSSTGEVEAWGYTAMKKLAQFRAQGTAKDYYFTRNFKMELHSGKKDES
>NC_008312.1|WP_011610967.1|1917667_1919488_-|Hsp70-family-protein
MIAKYIRLIKDEALKEIKNSTSGELKDQEIRWCLSIPAIWKNEDKDLMRRAARKAGLINSSDDEAERLFLVLEPEAAAIFCQEEDKNALTPGNKIMIIDCGGGTVDITVHKLVKDGGLDEVAPGTGGPFGSIYVDKSFQEYLTEKLSAEMVKGFHDQDPVGYLKMMEEWERTKCNFDPETSGDVIYFNIPTRLYNFISKRKAKILEQLADEQNGDDENIHLSYSTMENIFRITVHKLVKDGGLDEVAPGTGGPFGSIYVDKSFQEYLTEKLSAEMVKGFHDQEPVDYLKMMEEWERTKCNFDPETSGDVIYFNIPTRLYNFISKRKAKILEQLADEQNGDDKNIHLSYSTMENIFRPTLDGLVSTVKNQFKELGDEEVDIIFLVGGFSTSPVLRQRIKKEFGSKAKKIVMPPRPGVAILKGAASFGVAPGIIRARRSRLTYGVSSSREFNQFKDTIISQKQQSDNPENWENCLRVYKNNNDFLNWLLNNFDIQYSNHNHEQEKQQINSLKNALKNPKKLLEKFYNIYLMIVEPKKRYNQKHKQELKETVYLLNQKIQSQEILINELKRENEKLRKLKSSLLSKLSDRDRDTSNTITSDESRPQRDV
>NC_008312.1|WP_044136478.1|1942928_1943162_+|winged-helix-turn-helix-domain-containing-protein
MILKELPRDYVVDRNIWRGKIISNVIELRWGVKLKTTRIYKILNELNLSAQKAHINYANASQEQQKTFILSLKKIGI
>NC_008312.1|WP_155994328.1|1943206_1943395_+|hypothetical-protein
MSAQVFFTDGQKKNTAPEVPSNEKGFINKLNGMISVDAFTAQEYLKLKEKSKTEEVSDDFLQ
>NC_008312.1|WP_011610979.1|1944501_1944867_-|phage-holin-family-protein
MSILQLLILWFVTAVSLFIISKLPTGVEIDDFKIALISSVVFGFLNALVRPVLVAVVFPIKIVLSSFLFTLLLNMSIFGLAAWLVSGFRLRWGFWSALIGSVALGFINSFLYELLNRVVVS
>NC_008312.1|WP_011610980.1|1944893_1945985_-|redox-regulated-ATPase-YchF
MLRAGIVGLPNVGKSTLFNALVANAKAEAANFPFCTIEPNVGVVAVPDNRLNVLAQISNSAQTVPTRIEFVDIAGLVKGASKGEGLGNQFLSNIREVDAIVQVVRCFDSEDIIHVSGSVDPVRDIEVINLELALSDLAQVERRIERTKKQARTSKEAQTELEVLEKLEVVLNEGNSVKMAGLNKDESLIIKPLNLLTSKPIIYAANVSEDDLANGNDWVEKVRNIAAVENAQVVVISAQVESELIELPEEEITDYLKSLGVEEGGLKSLIKATYELLGLHTYFTTGEKETKAWTIKAGTLAPQAAGVIHTDFERGFIRAETIAYKDLVTSGSMTTAKEKGLVRSEGKDYLVKEGDIMLFRFNV
>NC_008312.1|WP_081432408.1|1951618_1951768_+|hypothetical-protein
MTYRWSSRPKLEATKVKRRRIKLDWKELEKDVKPNLEFKLAYKAKKNWS
>NC_008312.1|WP_011610986.1|1954985_1955288_+|helix-turn-helix-domain-containing-protein
MIYCLKTNQVLTRAELAKVLGRHESTITRWLTLYRAGGLKKLLEVKNVPGKTSKISPEILAGLQAKLSETIGFNSLGEIPKWLIEKYQVQLADKTVHKIF
>NC_008312.1|WP_155994329.1|1955349_1955784_+|hypothetical-protein
MKKIKKKLKLGLKVLLYELFGKGEKIRYFSQNETRLGLKTIPGKRITVKGVKPLGSTQWKRKNFYLYGAIEIKTQDCYFYEFSHLDGQCFQEFINQLSEEFNGSINFLQLDNGTFHKNVDFKEFIIPIFQLSHSLELNPIERFW
>NC_008312.1|WP_155994330.1|1955777_1955945_+|hypothetical-protein
MVTIKGEVTIWVNCQIIQQLQQKVSEILLKIDELTLASLTKWNYLIEAILSVTSS
>NC_008312.1|WP_155994331.1|1956045_1956186_-|hypothetical-protein
MSISKLFPRFGVSQNFLQTLTKKYQETGDIKPLPQGGSLPYQLNSE
>NC_008312.1|WP_044136482.1|1956797_1957007_+|hypothetical-protein
MVSNNWGVVTIKSPRTGKKNSSDKEIIKEILTECELIIDSYEKGIERLEKSEQQKEYYSGNKKSHTRKS

Crispr_ID: NC_008312_18

• CRISPR_ID: NC_008312_18
• CRISPR_location: 2180791-2180905
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NC_008312_18

Consensus_repeat	Method
TGGAGACGGGCTCTGGCTGCTGCAATTTTTTCTGGTC	CRISPRCasFinder

spacers of NC_008312_18

>18.1|2180828|41|NC_008312|CRISPRCasFinder
GCGTGCCTCTTTTCATTTCAGCCAACCTAGCCTGAGATTGT

CRISPR arrays and Neighbor proteins around NC_008312_18

CRISPR arrays

The CRISPR arrays of NC_008312_18

>merge|NC_008312|18|2180791-2180905|CRISPRCasFinder
TGGAGACGGGCTCTGGCTGCTGCAATTTTTTCTGGTCGCGTGCCTCTTTTCATTTCAGCCAACCTAGCCTGAGATTGTTGGAGACGGGCTCTAGCTGCTGCAATTTTTTCTGGTC

>NC_008312|18|15|2180791-2180905|CRISPRCasFinder
TGGAGACGGGCTCTGGCTGCTGCAATTTTTTCTGGTC	GCGTGCCTCTTTTCATTTCAGCCAACCTAGCCTGAGATTGT
TGGAGACGGGCTCTAGCTGCTGCAATTTTTTCTGGTC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_008312.1|WP_011611104.1|2165107_2166181_-|hypothetical-protein	unknown	unknown	unknown
NC_008312.1|WP_011611110.1|2174745_2175996_+|methionine-gamma-lyase-family-protein	unknown	unknown	gnl|CDD|311036
NC_008312.1|WP_011611103.1|2164054_2165092_-|MoxR-family-ATPase	unknown	unknown	gnl|CDD|223786
NC_008312.1|WP_011611111.1|2177666_2179061_-|WD-repeat-containing-protein	unknown	unknown	gnl|CDD|366375
NC_008312.1|WP_011611109.1|2173202_2174015_-|acyl-CoA-desaturase	unknown	unknown	gnl|CDD|224316
NC_008312.1|WP_011611108.1|2170543_2171125_+|6,7-dimethyl-8-ribityllumazine-synthase	unknown	unknown	gnl|CDD|234606
NC_008312.1|WP_011611107.1|2169562_2169763_+|photosystem-II-reaction-center-protein-PsbZ	unknown	unknown	gnl|CDD|167400
NC_008312.1|WP_011611117.1|2188782_2191536_-|DUF4347-domain-containing-protein	unknown	unknown	gnl|CDD|372982
NC_008312.1|WP_155994347.1|2182687_2182819_-|hypothetical-protein	unknown	unknown	gnl|CDD|279973
NC_008312.1|WP_052845764.1|2191816_2193793_-|substrate-binding-domain-containing-protein	unknown	unknown	gnl|CDD|224276
NC_008312.1|WP_011611113.1|2182027_2182204_+|hypothetical-protein	unknown	unknown	unknown
NC_008312.1|WP_011611105.1|2166251_2167331_-|5'-methylthioadenosine/S-adenosylhomocysteine-nucleosidase	unknown	unknown	gnl|CDD|350159
NC_008312.1|WP_044136524.1|2188291_2188489_+|hypothetical-protein	unknown	unknown	unknown
NC_008312.1|WP_011611106.1|2167778_2168330_+|hypothetical-protein	unknown	unknown	unknown
NC_008312.1|WP_081432530.1|2172813_2172924_-|hypothetical-protein	unknown	unknown	gnl|CDD|372648
NC_008312.1|WP_081432414.1|2184529_2184958_-|hypothetical-protein	unknown	unknown	gnl|CDD|373105
NC_008312.1|WP_044136523.1|2187782_2187962_+|hypothetical-protein	unknown	unknown	unknown
NC_008312.1|WP_155994657.1|2193827_2195102_-|ABC-transporter-substrate-binding-protein	unknown	unknown	gnl|CDD|380633
NC_008312.1|WP_081432413.1|2184007_2184478_-|hypothetical-protein	unknown	unknown	gnl|CDD|373105
NC_008312.1|WP_044136521.1|2183804_2184053_-|hypothetical-protein	unknown	unknown	unknown

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_008312.1|WP_011611110.1|2174745_2175996_+|methionine-gamma-lyase-family-protein	gnl|CDD|311036	pfam06838, Met_gamma_lyase, Methionine gamma-lyase. This is a putative pyridoxal 5'-phosphate-dependent methionine gamma-lyase enzyme involved in methionine catabolism.	0
NC_008312.1|WP_011611103.1|2164054_2165092_-|MoxR-family-ATPase	gnl|CDD|223786	COG0714, COG0714, MoxR-like ATPases [General function prediction only].	7.35339e-29
NC_008312.1|WP_011611111.1|2177666_2179061_-|WD-repeat-containing-protein	gnl|CDD|366375	pfam00931, NB-ARC, NB-ARC domain.	0.00105677
NC_008312.1|WP_011611108.1|2170543_2171125_+|6,7-dimethyl-8-ribityllumazine-synthase	gnl|CDD|234606	PRK00061, ribH, 6,7-dimethyl-8-ribityllumazine synthase; Provisional.	3.99343e-86
NC_008312.1|WP_011611107.1|2169562_2169763_+|photosystem-II-reaction-center-protein-PsbZ	gnl|CDD|167400	PRK02576, psbZ, photosystem II reaction center protein PsbZ.	8.61827e-14
NC_008312.1|WP_052845764.1|2191816_2193793_-|substrate-binding-domain-containing-protein	gnl|CDD|224276	COG1357, COG1357, Pentapeptide repeats containing protein [Function unknown].	3.96235e-31
NC_008312.1|WP_155994347.1|2182687_2182819_-|hypothetical-protein	gnl|CDD|279973	pfam01710, HTH_Tnp_IS630, Transposase. Transposase proteins are necessary for efficient DNA transposition. This family includes insertion sequences from Synechocystis PCC 6803 three of which are characterized as homologous to bacterial IS5- and IS4- and to several members of the IS630-Tc1-mariner superfamily.	2.08388e-06
NC_008312.1|WP_011611105.1|2166251_2167331_-|5'-methylthioadenosine/S-adenosylhomocysteine-nucleosidase	gnl|CDD|350159	cd09008, MTAN, 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidases. This subfamily includes both bacterial and plant 5'-methylthioadenosine/S-adenosylhomocysteine (MTA/SAH) nucleosidases (MTANs): bacterial MTANs show comparable efficiency in hydrolyzing MTA and SAH, while plant enzymes are highly specific for MTA and are unable to metabolize SAH or show significantly reduced activity towards SAH. MTAN is involved in methionine and S-adenosyl-methionine recycling, polyamine biosynthesis, and bacterial quorum sensing. This subfamily belongs to the nucleoside phosphorylase-I (NP-I) family, whose members accept a range of purine nucleosides as well as the pyrimidine nucleoside uridine. The NP-1 family includes phosphorolytic nucleosidases, such as purine nucleoside phosphorylase (PNPs, EC. 2.4.2.1), uridine phosphorylase (UP, EC 2.4.2.3), and 5'-deoxy-5'-methylthioadenosine phosphorylase (MTAP, EC 2.4.2.28), and hydrolytic nucleosidases, such as AMP nucleosidase (AMN, EC 3.2.2.4), and 5'-methylthioadenosine/S-adenosylhomocysteine (MTA/SAH) nucleosidase (MTAN, EC 3.2.2.16). The NP-I family is distinct from nucleoside phosphorylase-II, which belongs to a different structural family.	6.43775e-48
NC_008312.1|WP_011611109.1|2173202_2174015_-|acyl-CoA-desaturase	gnl|CDD|224316	COG1398, OLE1, Fatty-acid desaturase [Lipid metabolism].	6.9944e-107
NC_008312.1|WP_081432530.1|2172813_2172924_-|hypothetical-protein	gnl|CDD|372648	pfam13612, DDE_Tnp_1_3, Transposase DDE domain. Transposase proteins are necessary for efficient DNA transposition. This domain is a member of the DDE superfamily, which contains three carboxylate residues that are believed to be responsible for coordinating metal ions needed for catalysis. The catalytic activity of this enzyme involves DNA cleavage at a specific site followed by a strand transfer reaction.	6.15912e-10
NC_008312.1|WP_081432414.1|2184529_2184958_-|hypothetical-protein	gnl|CDD|373105	pfam14516, AAA_35, AAA-like domain. This family of proteins are part of the AAA superfamily.	3.70973e-21
NC_008312.1|WP_011611117.1|2188782_2191536_-|DUF4347-domain-containing-protein	gnl|CDD|372982	pfam14252, DUF4347, Domain of unknown function (DUF4347). This domain family is found in bacteria and eukaryotes, and is approximately 160 amino acids in length. There are two completely conserved residues (C and G) that may be functionally important.	2.80982e-48
NC_008312.1|WP_155994657.1|2193827_2195102_-|ABC-transporter-substrate-binding-protein	gnl|CDD|380633	cd19978, PBP1_ABC_ligand_binding-like, periplasmic ligand-binding domain of uncharacterized ABC-type transport systems predicted to be involved in the uptake of amino acids, peptides, or inorganic ions. This group includes the type 1 periplasmic ligand-binding domain of uncharacterized ABC (ATPase Binding Cassette)-type transport systems that are predicted to be involved in the uptake of amino acids, peptides, or inorganic ions. This subgroup has high sequence similarity to members of the family of hydrophobic amino acid transporters (HAAT), such as leucine-isoleucine-valine binding protein (LIVBP); its ligand specificity has not been determined experimentally, however.	1.1116e-92
NC_008312.1|WP_081432413.1|2184007_2184478_-|hypothetical-protein	gnl|CDD|373105	pfam14516, AAA_35, AAA-like domain. This family of proteins are part of the AAA superfamily.	2.98522e-59

Protein sequences

>NC_008312.1|WP_011611111.1|2177666_2179061_-|WD-repeat-containing-protein
MDIDTLVELADNLIFTKTREHLTSLQKEVLKGTLNGKKYPQIADDCQRHPDHIKQVGTKLWKLLSDILGKNIKKSNARSILEKIHFSHISNTGDDCVNINSNHINICGENKQSPTPKNKSSPTLIDQNQDNTNPENYYDLSEAPDLYPLCDRHSEVTTLKQLILQNHSRIITILGLTGIGKSTLTVELIAQIKNKFDYIIWRNIDNYSSCESLQINILKFLSQTDFTSQKKEKISKSQTINNQLIDYLRKYRCLLIFDNLQEIFASGKLAGTYLQEHENYGKFFQQIATLSHQSCLLLLSQEKPKIISTNNHCQTLKIDGLGKSAVAILKDINLTDEEQSLELINLYSGNPLWLNIIADAVEDLFNGNIAQILSCPSIYLGDLEPILDKYFQRLSELEKQVILWMASQETAVDIYNTSPDFPLLHSDLWKGIQSLKRRCLVTKQDNLFAVLAVLKQYIISNYLH
>NC_008312.1|WP_011611110.1|2174745_2175996_+|methionine-gamma-lyase-family-protein
MNSIEYLQAGEQELYPIFSEIDSLVKQNLRGVIDAFRHHRVGVHHFSGVTGYGHDDIGRETLDKVFAEIMGAEAAAVRIQFVSGTHAIACALFGTLRPGDEMLSVVGPPYDTLEEVIGLREEGQGSLKEFGISYRELPLTETGTINWQGLESAVTEKTRLALIQRSCGYSWRASLAISEIEKIVKIVKQKNSETVCFVDNCYGEFIEDREPIAVGADLVAGSLIKNPGGTIVMAGGYVAGRADLVEAATCRLTAPGIGSSGGATFEQNRLLFQGLFLAPQMVGEAMKGNHLTAYVFDKLGYAVNPLPFEKRRDVIQGIKLGSPEKLIAFCRAIQQYSPVGSYLDPVPGPMPGYDSQLVMAGGTFIDGSTSEFSADGPLREPYVVFCQGGTHWTHVAIALEAAIKAVGSSRDILQHP
>NC_008312.1|WP_011611109.1|2173202_2174015_-|acyl-CoA-desaturase
MTISTSKTLSLDWSIIGFMAFLHIGALFALFPSNFSWTAVGLALLLHWVTGGLGITLGFHRMLTHRSFKTPKWLEYFFIFCGTLACEGGVCDWVGLHRIHHQHSDNEQDPHDSHRGFWWSHMGWMLHKLPMKSEISRYTKDIANDPVYKFLQANFILIQFAFGILLFFIGGWSFVVWGIFVRIVAVFHCTWLVNSATHKFGYRTYDSGDSSTNCWWVAVLTYGEGWHNNHHAFQYSARHGLKWWEIDTTWMMIQLLQAFGLATNVKLATK
>NC_008312.1|WP_081432530.1|2172813_2172924_-|hypothetical-protein
MCHNKRPKRNKVFKELARWGKSSVDWYFECFTPLNY
>NC_008312.1|WP_011611108.1|2170543_2171125_+|6,7-dimethyl-8-ribityllumazine-synthase
MTVFEGTFTQVDSLRFAIVIARFNDLITGKLLEGCQDCLKRHGVDPDPDGTQVDYVWIPGSFEIPLVARQLAMSNSYDAVICLGAVIKGQTPHFDYVAAEVSKGIAAAAFQTGTPVIFGVLTTDTMQQALERAGIKSNKGWEYAMNALEMGSLMRQIKGSINSSPNNYSITGKTQALPITSNDFIESDISPEV
>NC_008312.1|WP_011611107.1|2169562_2169763_+|photosystem-II-reaction-center-protein-PsbZ
MLTFLTLLFQFLLLLLVVLSFILVVGVPVAYASPQIWSKGKPLIFIGSGLWLLLVISVGVLNFLVV
>NC_008312.1|WP_011611106.1|2167778_2168330_+|hypothetical-protein
MNDKKTILQAFLLEYEKLKEEQLKRIEFRDQMIYITLGIFGSILSFALSNKTNLYALLVIPWVCLILGWTYIVNDEKISAIGKYIRLTLTEKVKTQTDYSDIESIFSWEIAHRSDKRRKRRKIEQLIIDEITFVFSGLVALFTFWSLETNLPLVIHIFCTFELLLLAVLAIEIIIYADLAKGR
>NC_008312.1|WP_011611105.1|2166251_2167331_-|5'-methylthioadenosine/S-adenosylhomocysteine-nucleosidase
MVCAVILTAIRIEYMAVSAHLSDLREEIHPNGTIYERGQFSVGGQEWEVGIVQTGAGNSPAAMEAERAIAYFKPDVILFVGVAGGIKDVQLGDVVAATKVYGYESGKVAETFRPRPDVGRSTYNLIQRAKAEARKRDWLARFSDSAQPNVFVEPIAAGEKVVTNKKSDLFEFLQHNYGDALAVEMEGHGILKVAHANQQVSALIIRGISDLIDGKSRADEGGFQEIAARHASAFAFEVLGKFWLSRNQEYNGESHPKSSNFLADNFEESMKLQEVLIDYFNARQKPGQHLKSLVNISQIQVDTAAIDYNLPVRELIPNFYPEIFKSRENSLSFLRVFRSHLLKDSDEQLFVNKIIAMIR
>NC_008312.1|WP_011611104.1|2165107_2166181_-|hypothetical-protein
MFKLSIDEKIKLEEILTDYFNGLEKPSEGLKAMINISEVQIDITTIDYKLPVKELVTNFYSLILKKPEDLESFLIYLQNKLDPDERLTIKGYIEKLKPKRSRINQIPDHRSRMSKKRQQNHEIPTSKTPIKIKDNNKDNNKDNNIIVKYDLDELVYKFRKALDYQGVFAFSLGEEYTILKNYIIERILHELQEKTQRDYWSREIRLSRNLKSIDDDLKNNNINQITDLLAETDPLDVVLIIWNYNINKKNLNSMTDIFLSEIKTKCNCYLENKSRCLIIIFANVKIKQSIQGCINLSIPKSFQINELCDWFRGYLQKLQIQDDMINTCLRKLRNADGHLLSTYNTLEGIIDELRAIN
>NC_008312.1|WP_011611103.1|2164054_2165092_-|MoxR-family-ATPase
MNDLANRQYEGQGNDQKYERLKDEKGKEFLDIPIKKEPYIASKNLAEAVNDALYLRRPLLLEGEPGCGKTRLAYSIAYELGYPLKECYIRSTIRAEELLYTYDNIRRLYDLQEYRLIQGKLEEKDINNSPQVTNVIDRETYIELGKLGEAIELSDKNNIPSVVLVDEVDKADIDFPNDLLLVLDRLQFEVKEVKNLKYDALRGEEREDRKDFLPLIIITSNQEKELPKAFLRRCLFYYIGFPNKEDLRKIIINHFQQDVSPLFEVALTKFVELRDDISWRKKPSTGEFINWLRLLERGLPNNTTQEYQEIKAEVLRETKLYQLPFLHTLVKNQSDQNTIEKLKND
>NC_008312.1|WP_011611113.1|2182027_2182204_+|hypothetical-protein
MPLNDRGIPEITPGRRGPEGTWNKNNRTGNTFIKNLGEDPQFSAGEYRNGYQSILESL
>NC_008312.1|WP_155994347.1|2182687_2182819_-|hypothetical-protein
MNRESIGVEIMAYGLDLKQRVIVIIENASRIAKVVQVFGIGKG
>NC_008312.1|WP_044136521.1|2183804_2184053_-|hypothetical-protein
MSNQKNIKAVFSQILKAISPLSLPNKNIELHQLEAIKLITMVSFCFFGAATPEDLVIDSKQTPFNINNGIELRQLTFKDEKN
>NC_008312.1|WP_081432413.1|2184007_2184478_-|hypothetical-protein
MLDEVDKIFNYPEISRDFFLILKSWYEASNHKEILENLRMVIAYSTEYYGKLDIHLSPFNVGLPIELKEFIPEQVTKLADLYKLPITVVVSLMSIIRGHPYLIRLELYKMLEDELTIEELLKYTTTTESGIYQQHLSAHLKICLIRKILKQFLVKY
>NC_008312.1|WP_081432414.1|2184529_2184958_-|hypothetical-protein
MFNKYQPYLVCQKLKDKYFSSARKIVIPGRQEKLDSAFYIESYRIRKCYIEEKYYKNIEVPDCLIKIKMPKQMGINSLLTQIEAHAIKNKYKSIYLRFDKLIELENIKNINNFIKAFSKNIKRQFPDAPNRNRWDDKNGKIS
>NC_008312.1|WP_044136523.1|2187782_2187962_+|hypothetical-protein
MNSIKFNGLLDRYLPLLGLLLPKPILELAGIAFDHQLSDSQVRKTLISDDAPQFKLLSV
>NC_008312.1|WP_044136524.1|2188291_2188489_+|hypothetical-protein
MLAKKHISYGTQTMDGTASWDTFMFRVATTRKLGLSFFEYVHDRISQTMNIPAVATIIYVRGAWR
>NC_008312.1|WP_011611117.1|2188782_2191536_-|DUF4347-domain-containing-protein
MIVAHNNNATASSVISTFTKEVRTEKSLVAIDKSLEHYPQLVRGIAGQKSIVLLDGDRDAISQISEALSQTNAESLSIICHGEPGTLYLGNKLLKASNIDEYNYLLSEWGVKEIQLYACSVARDEEFIGRLQQLTGANIAASRDKVGNIALGGTSQLENQIGENQLVSEAIANYPGLLEIKFIPSQDSPVFYEFEDLPAYFAFGDFNKDEKLDRIVLEGSIDPDTLSPITTVFIEFGNGKGKFPKRSKSLELLGNPTDIQIGELDGNGNLDAVAVTSAYNTKTNETFGKITALKVDDTGKLTVDTQLNVINTDLISFADVNNDGLDDLSLSNYSSSFSTPSKIEIRLRKNQKFEAVDNSPFAAFDAKFNPVALGDFNGDGLMDRVKSVFNYSSGKTTISIDLGQKNGKFKPLKTSSIMLEDDGLVGVGEFNGDGNLDLAILSYSGSSGYYDYSDLGPSKQKISLLLGDGKGKFTLDTEVAFEEDSFPFLSIEDVNNDGLDDITVSSTETSRESSIRIDLSKTNGKLDKSVDVKVENLIDLVGGGDINKDGKQDLVVRTGGMDPDESQKIQVLLGQGKGKFKEGKTVKLEEQIDDAIVGDFNGDGNFDIATFKNNFSFGPYSPDLPGPYSPYSSPKTISVFLGNGKGNFSTTPKTLETKSESFLQSNNFALGDFNEDGNIDIAQAQFSTETTNQFSVLYNQGEKPPEAIKSNKNHTLKDEEVDLRLIGKGNINGTGNELDNNITGNTKRNRLKGLDGNDTLTGGQGNDMLMGGNDDDILTGGKGNDMLMGGNDDDTLTGGQGKDRFKFSSNSSFKPEDFGLDTITDFKSGQDAILLSQKTFDKLESTLGKGFSVIAEFDAVANNEEAETSDAFIVYSKETGDLFYNENGSEAGFGSGGNFAILEGKPNLKGTDFSIVK
>NC_008312.1|WP_052845764.1|2191816_2193793_-|substrate-binding-domain-containing-protein
MDKKEKNLPKEMSNSEFINHENSQRIYQKLRLKKSTLLKPISLLDTKISDCVEWLQNISLIKLAAILSQSALLFAVVSYVITIPSRQKQEIQNARKVLREESSYEYSDSRIAALKVLNKGCKSNPGLKAVSANMANLTLSPCQSLSFTQGSLKVNKYSMDLSYSNLTGANLSGANLAGINLQGSNLQGANLVNANLEGANLKDVNLEGANLARANLKKAILQNSNLDNSNLYGSDLQAADFSEANLVNMKALWANFHNAIFHRANLESANFNRANLRGADFYKANLENASLRFTDFGSTTNVIEAKLNPTNFRETQLKGADLWGAKMWSIFQIKQAKNWQETNRMPNWEQQIKQARLPRLRIALLKPENADSISDTYEFGMRRAANRRVEIWGISYPGGVKNEAKIIRQLIKDGMDGIILTPEDPVQSLDALKLARDAGVAITTVDFCFNPIDAEDLAIACYNTNSFQMGYDSGQYIAEWAQKNLQSKSVQIGLVDGAVYDRYYPYLQGVLKAINHSGIPFQIVDSVSIAFGSDIIKVKKLLEDNPDVQILWGGSNIATEVTVAAVAESALKNKVKVFGILDLSRNKATKLLNPNSPLQLIIEQSSIQIGYEAVKTTISVLRKEIDGADYQVYPVKHRLLTQNDPDIVSDILNDSSLE
>NC_008312.1|WP_155994657.1|2193827_2195102_-|ABC-transporter-substrate-binding-protein
MTIFAWACSPNPFKPLTLNVELTENVGSKNSDHTISTEGITEQTIRLGSVLALEGQEEILGNRMKSGLEAALDGQLVQEKKIQLIFKNDYYEPLVARKKAQRLIKSGIFLMIGNVGTPTAKETLPILKKNNVPAVGFFTGSELLRSRSELIINYRATYAEEIEAVVKIALNAGVKPYEICAYVQDDSYGMSGLKGLIYALVKAEVDQSILRPYEKVLEYKEKGNQGNSLLGPIGFYPRNTPYTKEGYNSLKQWEKNTGINCRLVVTAATSTNAARFINVAKKEGEPWVISSLSFAHKEELQFDLEEYGITDQVIITEVVPQLDSDLPIVQEAKSKLNSKFDHVSLEGYIIGKMTLKILKAIPGEINRESFLKQAAMSKFDLGGVVIDFTKGLNNSSNLVLISILTPQGFKDFHKYDSEKLFNNY

Crispr_ID: NC_008312_19

• CRISPR_ID: NC_008312_19
• CRISPR_location: 2353674-2353765
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NC_008312_19

Consensus_repeat	Method
GTTACAGGCTGAACAAGAGCGAGAGCGGG	CRISPRCasFinder

spacers of NC_008312_19

>19.1|2353703|34|NC_008312|CRISPRCasFinder
CTCAAAAAGCTGAGTCTCAAGCCAAAAAAGCTCA

CRISPR arrays and Neighbor proteins around NC_008312_19

CRISPR arrays

The CRISPR arrays of NC_008312_19

>merge|NC_008312|19|2353674-2353765|CRISPRCasFinder
GTTACAGGCTGAACAAGAGCGAGAGCGGGCTCAAAAAGCTGAGTCTCAAGCCAAAAAAGCTCAGTTACAGGCTGAACAGGAGCGAGAGCGGG

>NC_008312|19|16|2353674-2353765|CRISPRCasFinder
GTTACAGGCTGAACAAGAGCGAGAGCGGG	CTCAAAAAGCTGAGTCTCAAGCCAAAAAAGCTCA
GTTACAGGCTGAACAGGAGCGAGAGCGGG

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_008312.1|WP_155994352.1|2328887_2329025_+|hypothetical-protein	unknown	unknown	unknown
NC_008312.1|WP_011611197.1|2338370_2339288_+|sulfite-exporter-TauE/SafE-family-protein	unknown	unknown	gnl|CDD|376667
NC_008312.1|WP_011611199.1|2343202_2347798_+|helicase	unknown	unknown	gnl|CDD|223627
NC_008312.1|WP_044136543.1|2369007_2369805_-|precorrin-4-C(11)-methyltransferase	unknown	unknown	gnl|CDD|225430
NC_008312.1|WP_011611206.1|2362917_2364054_-|photosystem-reaction-center-subunit-H	unknown	unknown	gnl|CDD|224785
NC_008312.1|WP_011611204.1|2360071_2361457_+|hypothetical-protein	unknown	unknown	unknown
NC_008312.1|WP_011611203.1|2359258_2359612_+|hypothetical-protein	unknown	unknown	unknown
NC_008312.1|WP_044136539.1|2335383_2336226_+|glycosyltransferase-family-2-protein	unknown	unknown	gnl|CDD|224137
NC_008312.1|WP_011611211.1|2374238_2375345_-|TIGR00303-family-protein	unknown	unknown	gnl|CDD|235300
NC_008312.1|WP_011611205.1|2361895_2362381_+|cytochrome-P450	unknown	unknown	gnl|CDD|375733
NC_008312.1|WP_011611198.1|2339840_2341994_-|polyribonucleotide-nucleotidyltransferase	unknown	unknown	gnl|CDD|236995
NC_008312.1|WP_044136536.1|2329101_2329341_+|hypothetical-protein	unknown	unknown	unknown
NC_008312.1|WP_011611207.1|2364598_2368258_-|chromosome-segregation-protein-SMC	unknown	unknown	gnl|CDD|274009
NC_008312.1|WP_011611200.1|2348273_2349449_+|AAA-family-ATPase	unknown	unknown	gnl|CDD|379114
NC_008312.1|WP_011611196.1|2336376_2337459_+|glycosyltransferase-family-4-protein	unknown	unknown	gnl|CDD|340838
NC_008312.1|WP_155994353.1|2330507_2332610_-|hypothetical-protein	unknown	unknown	unknown
NC_008312.1|WP_155994661.1|2354017_2359255_+|tetratricopeptide-repeat-protein	unknown	unknown	gnl|CDD|378942
NC_008312.1|WP_011611194.1|2333972_2335067_+|glucose-1-phosphate-thymidylyltransferase	unknown	unknown	gnl|CDD|273500
NC_008312.1|WP_011611210.1|2373079_2373454_+|hypothetical-protein	unknown	unknown	unknown
NC_008312.1|WP_011611209.1|2369917_2370784_-|prolipoprotein-diacylglyceryl-transferase	unknown	unknown	gnl|CDD|376615

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_008312.1|WP_011611197.1|2338370_2339288_+|sulfite-exporter-TauE/SafE-family-protein	gnl|CDD|376667	pfam01925, TauE, Sulfite exporter TauE/SafE. This is a family of integral membrane proteins where the alignment appears to contain two duplicated modules of three transmembrane helices. The proteins are involved in the transport of anions across the cytoplasmic membrane during taurine metabolism as an exporter of sulfoacetate. This family used to be known as DUF81.	2.47862e-34
NC_008312.1|WP_011611199.1|2343202_2347798_+|helicase	gnl|CDD|223627	COG0553, HepA, Superfamily II DNA/RNA helicases, SNF2 family [Transcription / DNA replication, recombination, and repair].	4.02316e-98
NC_008312.1|WP_044136543.1|2369007_2369805_-|precorrin-4-C(11)-methyltransferase	gnl|CDD|225430	COG2875, CobM, Precorrin-4 methylase [Coenzyme metabolism].	1.83643e-119
NC_008312.1|WP_011611206.1|2362917_2364054_-|photosystem-reaction-center-subunit-H	gnl|CDD|224785	COG1873, COG1873, Protein implicated in RNA metabolism, contains PRC-barrel domain [General function prediction only].	0.000979591
NC_008312.1|WP_011611207.1|2364598_2368258_-|chromosome-segregation-protein-SMC	gnl|CDD|274009	TIGR02169, chromosome_segregation_protein_related_ptotein, chromosome segregation protein SMC, primarily archaeal type. SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. It is found in a single copy and is homodimeric in prokaryotes, but six paralogs (excluded from this family) are found in eukarotes, where SMC proteins are heterodimeric. This family represents the SMC protein of archaea and a few bacteria (Aquifex, Synechocystis, etc); the SMC of other bacteria is described by TIGR02168. The N- and C-terminal domains of this protein are well conserved, but the central hinge region is skewed in composition and highly divergent. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins].	0
NC_008312.1|WP_011611211.1|2374238_2375345_-|TIGR00303-family-protein	gnl|CDD|235300	PRK04447, PRK04447, hypothetical protein; Provisional.	6.09387e-170
NC_008312.1|WP_011611205.1|2361895_2362381_+|cytochrome-P450	gnl|CDD|375733	pfam18306, LDcluster4, SLOG cluster4 family. Family in the SLOG superfamily, observed as a standalone domain with little informative genome context, although related families in the SLOG superfamily are predicted to function in diverse conflict contexts.	4.89147e-56
NC_008312.1|WP_011611198.1|2339840_2341994_-|polyribonucleotide-nucleotidyltransferase	gnl|CDD|236995	PRK11824, PRK11824, polynucleotide phosphorylase/polyadenylase; Provisional.	0
NC_008312.1|WP_044136539.1|2335383_2336226_+|glycosyltransferase-family-2-protein	gnl|CDD|224137	COG1216, COG1216, Predicted glycosyltransferases [General function prediction only].	2.06958e-34
NC_008312.1|WP_011611200.1|2348273_2349449_+|AAA-family-ATPase	gnl|CDD|379114	pfam13304, AAA_21, AAA domain, putative AbiEii toxin, Type IV TA system. Several members are annotated as being of the abortive phage resistance system, in which case the family would be acting as the toxin for a type IV toxin-antitoxin resistance system.	3.51464e-19
NC_008312.1|WP_011611196.1|2336376_2337459_+|glycosyltransferase-family-4-protein	gnl|CDD|340838	cd03809, GT4_MtfB-like, glycosyltransferases MtfB, WbpX, and similar proteins. This family is most closely related to the GT4 family of glycosyltransferases. MtfB (mannosyltransferase B) in E. coli has been shown to direct the growth of the O9-specific polysaccharide chain. It transfers two mannoses into the position 3 of the previously synthesized polysaccharide.	1.72016e-100
NC_008312.1|WP_155994661.1|2354017_2359255_+|tetratricopeptide-repeat-protein	gnl|CDD|378942	pfam12770, CHAT, CHAT domain. These proteins appear to be related to peptidases in peptidase clan CD that includes the caspases. This domain has been termed the CHAT domain for Caspase HetF Associated with Tprs. This family has been identified as a sister group to the separins.	1.38533e-54
NC_008312.1|WP_011611194.1|2333972_2335067_+|glucose-1-phosphate-thymidylyltransferase	gnl|CDD|273500	TIGR01208, rmlA_long, glucose-1-phosphate thymidylylransferase, long form. The family of known and putative glucose-1-phosphate thymidyltransferase (also called dTDP-glucose synthase) shows a deep split into a short form (see TIGR01207) and a long form described by this model. The homotetrameric short form is found in numerous bacterial species that incorporate dTDP-L-rhamnose, which it helps synthesize, into the cell wall. It is subject to feedback inhibition. This form, in contrast, is found in many species for which it serves as a sugar-activating enzyme for antibiotic biosynthesis and or other, unknown pathways, and in which dTDP-L-rhamnose is not necessarily produced. Alternate name: dTDP-D-glucose synthase.	1.33141e-172
NC_008312.1|WP_011611209.1|2369917_2370784_-|prolipoprotein-diacylglyceryl-transferase	gnl|CDD|376615	pfam01790, LGT, Prolipoprotein diacylglyceryl transferase.	2.20608e-97

Protein sequences

>NC_008312.1|WP_011611200.1|2348273_2349449_+|AAA-family-ATPase
MDKQPIDNLTIHHFRGIRDLTLENLGQINLLVGVNNSGKTSVLEAIYTYCNPLEPLEWLNTAWRREVKSSRKSKLESLKWLFPQNTHNNSDSFYQGETWVSGNSTFGFLESKATYQEIEEIWDSTKDNDEEDEQENLINEIDIDDNEIRRGAGLKLRFTPLKLIPKSDIFDYENDEKNQEKFISKNFRIWENQPLTILNKYKGNWLSVDIVTPFSHRIEQLQIKLLTGAIFQGFKPEIIELISMMDSEILDLEILDITGKNSRLYVRHKTLGITPLSSFGDGVSRLLFMALTIAKLKDGILLIDELETAIHTEALLFSFSWLVKWCRKTNVQLFATTHSLETVDAMLNASKLRNDLVLYRLYQKDMQTQAIRIDQVKLTRVRENLGLEVRW
>NC_008312.1|WP_011611199.1|2343202_2347798_+|helicase
MAILHSFWVTEHEQPSFLFIWGEAWHRVTEEDAGEVEKITNNPYSITLDELLKLSEANIYLSLEKHKKSTNQTLGIPTKLSESNQKLYPIHSAISLSEIPENLYIYPWKIEGICLEPDEAIKFLQSIPLGQTTESFIGSDLKFWSHLARWSLDLLARCKFLPSIEQRSITQEFITTWQPLIDSSIDQTRLKNFAQQMPLVCRTYNLDWQLHPSLESLQIITKNNSYSNLPRLQSSQEIIQDFLKNTIDKQIRQLSAEISLTETTSLNSSIRQWLKSLSGKLSLKLPAPQETKKIQKILDNWKSPLQEYQAIENKFVACFCLHSPSNNSQQWKLEYCLQGLDNPDFLVDAKTIWENPVASLNYQGKTIKLPQETLLKGLGLASRIYPIIEPSLQEATPQYCLLTSQQAYDFIKSGSGRFIDSGLGVILPPSLANREGWASRLGLSIQATAPKMKKTEKLGLKSLLNFKWQLSIGGHKLTKAEFEKLVSQDSPLVEVNGEWVELQGQDVRAAKNFFASRKDQMSLSLEDALRLATGDTQTVEKLPVVNFEAGGQFQELLDTLTNNRSLEEVSTPENFRGELRNYQARGVSWLSFLERWGLGACLADDMGLGKCVLHDTEIYVNGMVMEAEQIWQAYAGEAEFDGEGFWTEPNKELLVNSLDETTGKIVFARIRRLYRQWVREKLRKVRLKDGSSITITCRHKLFIRDSWKNDFQVGDDVCVPAKLMWDGKPEDPDVVKFVAWQVAEGWERVNSGMFGVSQKGKDVLEGLLEVFSRLGKRYDIKINCPKVVAHGSKKNCYEFSAHSLEYRKFLEEKRYGWGKRSHEKTIPLFIMQADLDSVRVFLSNYFDAEGWVNKTVRCVEISTASSQLIQELSILLRRFGVWMKISPQQKCATNGTGVFCTYYIGTFGGNSARCFLQEIGFNDSGKQENLKSICEKIADSNVEGIPASDIVAELVEKTQLPVGSLGIQDPIYMDGCQDFSPTSLEKVINSIEDIISGAGEEEYGQLKSSKLRNKTLEAYSLLNILELEIYKTRLQKLLNQEVYYCQIESIEEMEYEGWVYDFEVSKYHNFVANNIICHNTIQTIAFLLKQQEQKALKGPTLLVCPTSVLGNWEREVKKFGPTLKAIVHHGDKRAKGKGFATAVKDTNLVITSYALLHRDEKILETIKWQSVIVDEAQNIKNPEAKQSQAARKLDASFRIALTGTPVENRLSELWSILDFLNPGYLGQKQFFQRRFAIPIEKYGDTSSLQILRSLVQPFILRRLKTDKDIIQDLPEKQENTIFCPLANEQALLYQNIVENSLAEIDTVGGIQRKGKILALLIKLKQLCNHPVLLQIKKGSRKKVEITDKNSGKLQRLGAMLEEIISEEERAIIFTQFAEWGKVLQPYLQKSLGREVSFLYGSTQRSKREEMIDQFQLDPQGPPVMILSLKAGGTGLNLTRANHVFHFDRWWNPAVENQATDRVFRIGQTRNVQVHKFVCTGTLEEKIHDLIESKKELAEQVVGAGEKWLTELDTDQLRNLLILDRNQVIKEE
>NC_008312.1|WP_011611198.1|2339840_2341994_-|polyribonucleotide-nucleotidyltransferase
MEEIDKSISFDGRDIRLKVGLFAPQAGGAVMIESGDTAVLVTATTAKGREGIDFLPLLVDYEERLYAGGKIPGGFLRREGRPPEKVTLTSRLIDRPLRPLFPSWLRDDIQIVATTLSMDEEVPPDVLAVTGSSVAVLLAKLPFYGPMAAVRVGLVGDDFIINPTYREVKNGDLDLVVAGSPQGVIMVEAGANQLPEQDIIEAIDFGYEAVCDLIQAQREIIAEMGIELVELEPPEVDPTLENYIKEKATEQIKEILSQYDLDKNQRDEKLDEIKDSLAESITELPEEEAVRAMVESESMLLGNAFKSVTKKLMRQQIVAEGIRVDGRKLDEVRPVSCRVGVLPSRVHGSSLFNRGLTQVMSAVTLGTPGDAQELADDLHPQDEKRYLHHYNFPPFSVGETKPLRQPGRREIGHGALAERALIPVIPKSDIFPYVIRVVSEVLSSNGSTSMGSVCASTLGLMDAGVPIVKPVSGAAMGLIKEDEEVRILTDIQGIEDFLGDMDFKVAGTDSGITALQMDMKITGLPIEVIADAIHQAKPARIHILDKMLSVLDLPRPDMSPYAPRLLSFKIDPEMIGLVIGPGGKTIKGITEETGVKIDIDDDGTVTIAAADGEKAKQACNIIQGMTKKLNPGDVYVGRVTRIIPIGAFVEVFAGKEGMVHISQIADYRVGKVEDELAIGDEVIVKVREIDSKGRVNLTRLNIHPDEAAAARANAMNY
>NC_008312.1|WP_011611197.1|2338370_2339288_+|sulfite-exporter-TauE/SafE-family-protein
MEHIELLYISFSGLFAGVLAGFLGIGGGVVMIPVLVTLGYQPVQAVGTTTLSILITAISGSIQNLQMGNLTISRVIAIGFPALITAQLGVYLENQFSSRWLLFAFGLFLILNIYLVEFRKQVTKRKKEQEELEQNLREDVLVKLENRNNQDFAEEFALPITDESLLLIEPIIKKINSQIPEKYMKPIARITTGSLAGLLAGLFGLGGGVILVPLQILLLGEKIKVAIPTSLGVIVITAFSACIGHAVRGNVLWETGLLLGFSGLLGVQFSTRSMKKLPDEVISFAFRALLAIISIYIFWEGVNIG
>NC_008312.1|WP_011611196.1|2336376_2337459_+|glycosyltransferase-family-4-protein
MSNKVLINLSVLIPQPTGISVYANNILPQLQPLNPILLVANNIPKFNCHLIPNNMTPAQGTIGHFRRLFWTQFQLSNISKKLQANLIFSPLPEAPLFSECPYIVMAHDLIPLRFPKPGSRLTAYFKYYIPQVLSQAKHIICNSQATAKDITDFFKISPQKITPIPLGYDSQRFQFLDLPTKNYFLYLGRHDHYKNLHRLIEAFTNLPNFSEYELWFAGPTDNIYTPTLKTQIKELGLTNLVKFLDYVSTEELPKIISQAIAMVFPSLWEGFGFPVLEAMACGTPVITSNISSLPEVAGDAAILVNPKNVGEITDAMNIIAQDGGERSRLMSLSLARAKEFSWEKTGLATREIIQQFSVSG
>NC_008312.1|WP_044136539.1|2335383_2336226_+|glycosyltransferase-family-2-protein
MYFLTVNYYSTQLIKKLINSIKLITDLFSHIVIINNSTDDKSIYQLQNNKTIIINSETNLGYGKGCNLGLSWIYNQNPQAIVWLINPDAYLLPDSLEKAYHFLGKNPEISILGTTVYEPTGKVWFGGGNFIPETGKIIANNFFYKTETSITDWVTGCSMLINMNNFEKCPEFDEDYFLYYEDFDFCRRYKKQGHKIAITQTISVIHQPSSITSKQPGLKLEYSIYSYLLSLAKHTNKLVLIYRLLRITIAALVSLLIDYKIARVKIKAISKFIRCNRRFL
>NC_008312.1|WP_011611194.1|2333972_2335067_+|glucose-1-phosphate-thymidylyltransferase
MKALILSGGKGTRLRPLTYTGTKQLVPVANKPILWYGIEGIIAAGVTDIGIIISPETGEEVQELTGNGEKFGGNITYILQDKPAGLAHAVKTAQPFLGDSPFIMYLGDNIIESQLGNFLDTFKKKQLDALILLRKVPNPTAFGVAKIDDNGRVLRLVEKPKVPPSDLALVGVYLFSKKIHNAIANIKPSERGELEITDAIQYLIDQQISGEEPEISVEASILEGWWLDTGKKDDLLSANQIILDTRIIKSINGEIDSKSKIIGRVKMGKNTKLINSSVRGPVIIGDNCYLENCFIGPYSSIADNVTLIDVDIEHSVILQGAKIIEINQRIVDSLLGRRAQLINAPQHPKALRFMIGDDSQIELT
>NC_008312.1|WP_155994353.1|2330507_2332610_-|hypothetical-protein
MTNIIIFLTVVLIIIAITSIYVSNEDTIYWWDFVGYQNAANNLTNLFRVSFQRAIDDINGSLSQQKNYLITLPLIPFLYIFGNQRIIYILSINLIYLLPFSLLLGAIAIKLIPVHSRWVFWSTVAIALLIPMSWSPSLRGYPDIGATLFILLGALFYLKNIRLTTWWQLPIIGFCLGISIVLRRHFAYSVIAFIGAISCQIILDSLTNFKFSKTSVKRLLEGAIKISLISLTCFLTISIFAWGFIQNSLTENYRTLYAAWSLSIPDIFWRYSCFYGLITLLLVAIGFFVGVMRKFLIPSTTIFLLLFGIFSVAEWLILLRYGNIHYSLHLTPIVVLGLSSFIWITIHTFRRKTRLIIFSIAGIYLIINLIFGLTPIGKFNNPLRPLFASNFSPLIRSDYNQVLQLTDYLNKLAPNQELVYVAASSNQFNANIIRNANRIINPKNWSNLKAISKPHIDTRDTYPLPELLAAQYIVIAHPFQRVLLTDEQVLKPGQQDLVRFVYDAFTQNLSISQDFQKLPEEFVLDGGVTVSFYQRIRPTSISTALQTLSAMQKQVPQRPGRQLDWISLNQSPYITYNYSAVTQVSDSAYNLMTDPSDITKQTSKYFLYLGQLSSSIKITGKLDFLHQECNGLSLKFSILDDQGILLDTNVNNYFPGVDSDFIFSLAGKNPVYLLLENISIDGDNLTDKCGWIINHLVVDD
>NC_008312.1|WP_044136536.1|2329101_2329341_+|hypothetical-protein
MGIHLGRLRRVDGYGKEVLILTFLRVVSPEVGEILVRPTAVVTKENLRMTNSDNVVLSESQDLETIPGQYLYLWSIAFL
>NC_008312.1|WP_155994352.1|2328887_2329025_+|hypothetical-protein
MELTLINIMAIAASGLMLIVTGGIIYLTASEWRDRRRQKRDKSGP
>NC_008312.1|WP_155994661.1|2354017_2359255_+|tetratricopeptide-repeat-protein
MLIFPSLRRRLLPKTQNEIYDRLSSTVGTREKLPDQLLSQLDFLIQVLRVTAESNGDSKVVYPFLQQNLDKLDDNFADILRNWATANFSEVEADVAKSIAIDIIDFSYNIQEFPLGSKANNMEISIAGYEVVLKVFTYKSHREKWAMTQNNLGVAYSKRIRGDKAENIEAAIAAYQQALLVYTQTDFPINWAMTQYNLGIAYSDRIRGDKAENIEAAIAAYQQALLVYTQTDFPMDWAMTQNNLGIAYRNRIRGDKAENIEAAIAAYQQALLVRTQTDFPMDWAMTQNNLGIAYRDRIRGDKAQNIEAAIAAYQQALLVYTQTDFPMDWARTQNNLGIAYRDRIRGDKAQNIEAAIAAYQQALLVYTQTDFPINWAMTQYNLGIAYSDRIRGDKAENIEAAIAAYQQALLVYTQTDFPMDWAMTQNNLGIAYRDRIRGDKAQNIEAAIAAYQQALLVYTQTDFPMDWAMTQNNLGIAYRDRIRGDKAQNIEAAIAAYQQALLVYTQTDFPINWAMTQYNLGIAYSDRIRGDKAENIEAAIAAYQQALLVYTQTDFPMDWAMTQNNLGIAYRNRIRGDKAENIEAAIAAYQQALLVRTQTDFPMDWAMTQNNLGNAYRDRIRGDKAENIEAAIAAYQQALLVRTQTDFPMDWAMTQNNLGIAYSDRIRGDKAENIEAAIAAFQQALLVRTQTDFPINWATTQNNLGLAYSDRIRGDKAENIEAAIAAYQQALLVRTQTDFPMDWAMTQNNLGIAYSDRIRGDKAENIEAAIAAFQQALLVRTQTDFPINWATTQNNLGLAYSDRIRGDKAENIEAAIAAFQQALLVYTQTDFPMDWAMTQNNLGNAYRDRIRGDKAENIEAAIAACQQALLVYTQTDFPMDWAMTQNNLGIAYRNRIRGDKAENIEAAIAAYQQALLVRTQTDFPMDWAMTQNNLGNAYSDRIRGDKAQNIEAAIAACQQALLVRTQTDFPMDWAMTQNNLGNAYSDRIRGDKAQNIEAAIAACQQALLVYTQTDFPMDWAGTQNNLGIAYSDRIRGDKAENIEAAIAAFQQALLVCTQTDFPINWAATQNNLGIAYRNRIRGDKAQNIEAAIAAYQQALLVRTQTDFPIDWAMTQNNLGNAYSDRIRGDKAQNIEAAIAAYEQALLVRTLEADPITHLKTTSNLGDLYFDNQNWQLAADNYKKAITAVELTRSWATTDDRRQEILKENINIYNKAIQAYIHLKKLEQALEIAERSQARNLVQLLTNRDLVPQDNVPPEITQQLQQQQKEIRVNKGELEKVRKQLSQQNTQEKTSLEKSEKQLNEELQKLRQQLEKTFNQIQEYDPTFRLTQEVQPIAFREIQQLATEQQTAIIEWYIMGEKFLAFTLVPPTSTATSELFMWQSTEDGLKNLQEWAQEYVDKYYELKIAHQENQEKAKKLQQEWETKITTRLEKLGEILHIKEILQPILESECQRLTLIPHSFLHFLPLHILPINNPENSQENPEKKYLQDYFNQGVSYAPSCQILQKVRERNNQEFQSLFAIQTPTPDLYGQDLGIISIIKKQFNNVEIIPKNQATKSALINDSKLSLANSVLFFCHGVFEPFSPLDSGLILADEKLTLGDIIQNLNLSKCRLVTLAACETGLTDILNQEYVGLPSGFLLAGSTNIIASLWSVRVDATALLMLRLYQELKKYDNIIIALKIAQNWLRDTKVQELKEWVIKSPLKIIWQEKLEETFTKMENLEGVNCKPYNSPYFWAGFCVVGKGE
>NC_008312.1|WP_011611203.1|2359258_2359612_+|hypothetical-protein
MYEDYYTIKTFIDIINDQAIPPEEFPNLLNLVEQMPEDSEEIANQIDDWLREESRLEIQEAYRNQVKKLPEIEWRKLGFGGAKAPPGNENESTKELILNAIKKNTPEPKPEENSEKK
>NC_008312.1|WP_011611204.1|2360071_2361457_+|hypothetical-protein
MKNLTISLLAFHLYSPFLESSETNDQEGKLLWENLTQLGEKSLPFLGLKYLPHQLICYDQNGNYNLDFKTHENNWWMSRSKQTIDLGVIEIEECKIAGNLQPFILNDTYAADLTLTPKLSEEKLDISQLKKFPINNLLPSSIQASLGETFLIYGEIDSEVNPQQIADECVENLFNSAQIEPVFLSQSKLFNSLLFEYQGTELNQNNNQSQPFKILVLLKNSQAETLKLAEKSYEWILQLLCCRHKINFIYQESRNLYPKARKSYGKLETQMENFSKIIEDPKTRLESLKEILEKIPKDYLYYSRYVRDLKTHKTALETNIKNYEICLEKIKKTSEIPPYWQEFLNKTSHIRHRQIETDINYLSPGQQLFEQLVNAIRGIAETDQLESDRHLERTIQIIGIGLGTGGIIASSTGHIDVPLTFKSTGKIETIHPVILTLILSILATLLAGGITWHLTKPKNKK
>NC_008312.1|WP_011611205.1|2361895_2362381_+|cytochrome-P450
MKKTIIGVMGPGNSATSTDLKNAYKLGQLIAQESWVLLTGGRNIGVMDAASRGAKFLNGLTIGILPDNNLHSISEAVDIPIITDMGNSRNNINVLSSDVVIACGMGVGTASEIALAIKNNKKVILLNNNLESQAFFVALSPQTVFVVNTPEAVIEVVKNLI
>NC_008312.1|WP_011611206.1|2362917_2364054_-|photosystem-reaction-center-subunit-H
MRSEKNRQRSELLGTQIITRDKGKRLGVVSQLWVDVDKREVVAIGLRDNILAVAGIPKFMFLKDVCEIGDVILVDDEEVIEEDIDTEAYSGLINSEVLTENGDFLGRVRDFKCDVRDGKVLSLIIASIGIPQIPDQIISTYEMPIDEIVASGPNRLIVFEGSEEKLQQLTVGVLERLGLAEAPWQKEEEGLYNPPTVNPDNQLGPGQLVSREPIRTARRSTQETWDDNWVEPEPVESRVIEPEPVYRKYYEQEMAPPPRQREQEAVYDNYYEPEPVAPPSARQVRVEPADNDYYEEEGNWGDSETGYDNEQDRYQKKEDGYQKKEDGYQKKEYKATSEYEYDEEIDRDAWADDEAPKPYQAPRVNIPEKTKVPEYEDY
>NC_008312.1|WP_011611207.1|2364598_2368258_-|chromosome-segregation-protein-SMC
MVHIKCLELTNFKSFGGTTTIPLLPGFTVVSGPNGSGKSNILDALLFCLGLSTSKGMRAERLPDLVNNKLAGRKTVETIVTVTFDLEDLSSQKNGQNELGSVQPQVPEVEENGYKTRETKDPFEITNSFDSLLEWSISRRLRVTKQGTYTSTYYMNGQPCTLSQLHEQLNQLRVYAEGYNVVLQGDVTGIISMKSRERREIIDELAGVAQFDRKISLAKEKLDLVKEQEEKSRIVERELEKQCGRLSQDCVKAKKYQQLRGELEEKSLWQTILRWQNLQKQEWKLRENIESGDRSVTEFNQNIQAKETEVRQAQTELDDLNAQVKALGEEQLLALQSSLATQEAERCQFQKKHKELEATIQQTQKNLSQLEQEVNKHQQNLEVLATEIVVQTQNVSFLEAGRNEAQEILNQQRGSASAIADTAEAWVKEQGQLHHQIESLQQTLNPQRTEQARVRERAYQLEKQIQEQQESLGVLGEEIEGYGKHYEQVKESKETARYQVESLTKQLEAVEQDLKVQQDTQTRLLQEQRDRQRKLDKLEAQQQAIQEATGTYATKMLQQSGISGICGLVAQLGRVEPKYQLALEIAAGGRLGNMVVENDGVAALGIEFLKRHKAGRMTFLPLNKIRYPAQKRDGSLGWGAAGFIDYAVNLIECDPHYQDIFAYVFGSTLVFDILVNARKYLGKYRIVTLDGEILESSGAMTGGSMSRRSGSLHFGTVDGRDLTEIGEMESHSQRLQEIDIVLERCLVEIEGLKEKVKERSQAFMEGKQYFRETELKVSQIEAELQRLIRQQEQGQGQLEKNNQELVDAHNRLMSLDQEIPAQEVQLTELRKTLAELEKSHTHSEWQQLQTMIRSQEVVLQEQEATLRSAEQKLQHLENQQRLLQEKVEAISRRCSEYQEQELDAYNTIKEVKSQILVVDEEVGKTREGMAKVEERLGTEKQKRDEAEANLRELYLAKQGLEWQLQKLQESQQGRREQLVPLQILLEEQKAELPDPLPIVPEKIKMTELEKEVRSLQKQLQALEPVNMLALEEYEQTQKRLEELSQKLGTLEEERTALLLRIENFTTMRQRSFFEAFNAVNKNFQTIFAALSEGDGYLQLDNQEDPFNSGLNLVAHPKGKPVQRLASMSGGEKSLTALSFIFALQRYRPSPFYAFDEVDMFLDGANVERLAKMIKQQAEGAQFIVVSLRRPMMELSERTIGVTQARGAYTQVLGIKMSQH
>NC_008312.1|WP_044136543.1|2369007_2369805_-|precorrin-4-C(11)-methyltransferase
MNDTKSLTPAVYILGAGPGAPDLLTVKADKILTTADVILYADSLVPKQMLRNVRHDAEIITTANKTLEEILPLMIDRVRKGLSVVRLHSGDPSLYGAVYEQMQLLAEAGIDFEIVPGISAFQDAAAKLKVELTVPGLVQTIILTRISGKATAVPSREELGSLAAHGASLCLYLSARYVWEAQEKLMEHYSADIPVAICYRLGWPDEKIWVVPLEKMALMTEEKQLVRTTLYVISPALEKLEKVGRSGLYNPEHNHLFRGKHNRKN
>NC_008312.1|WP_011611209.1|2369917_2370784_-|prolipoprotein-diacylglyceryl-transferase
MTVEITLLPLGFQFTSPGPIIFQLGPLIIRWYGLLIAAALLIGVTLSQYLAKLRHVNPELLGDLVIWLVLAAIPGARLYYVLFEWEQYQQNPIDMIAIWKGGIAIHGAIIGGAIAALIFARLNKISFWQLADLVAPSLILGQVIGRWGNFFNSEAFGSPTDLPWKLYIPPERRPLDLISFDYFHPTFLYESLWNLIVFGLLIFLFFRDLRGRPRLKPGTLFLVYMVAYSSGRIWIEALRTDSLMLGPLRIAQFVSLAGILLGLIGLGWLYLLKRPLLDVLPPEVKETN
>NC_008312.1|WP_011611210.1|2373079_2373454_+|hypothetical-protein
MELLQEQIFALTKKVEVIYRIIEQLNDKVSNYIIIEKVNKYQTTETDSNLQQGNELQEKYDYFNPELEHKDVLVDDNYLNKSSQNIDGELTSNIQIQRLTAQLTAAYNRIASLEEQLLSKKIKF
>NC_008312.1|WP_011611211.1|2374238_2375345_-|TIGR00303-family-protein
MIRVYTQRQQGKNWLQRYQGYKPIFGCILGFTDTGLIPGISAAGATPQDRQYTCLADIEFLYNGLQLQPQYPLPPLEAGASPVLITKAIIDTLNIPLYLFNAGLYHKPTVPTIDLGGAPARCLTSGHALDLATIQHLLEVGSYWGRKLADEAKDSYVILGECVVGGTTTALAVLLGLGIGAIGKVNSSHPQCNHDQKLAVVHQGLQEAGFHSALPVSEPLKLVAAVGDPMQIVVAGMGMAASLKVGVMLAGGTQMLAVYALMQVLAEKLSLLWRPENIVVGTTRWVAEDPTGDTVGLAQEIGCVPLMATQLHFDESCYPQLQAYERGYVKEGVGCGGCAITAHLYRNWNQTQLLKAVEDLFASFIFLE

Crispr_ID: NC_008312_20

• CRISPR_ID: NC_008312_20
• CRISPR_location: 2407713-2407829
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NC_008312_20

Consensus_repeat	Method
TTTATTATATATCGGGTCTATAAATAATTTTCT	CRISPRCasFinder

spacers of NC_008312_20

>20.1|2407746|51|NC_008312|CRISPRCasFinder
AGATTTCCTATTTTGAACATATTCTTTAGTCTTAGATCAATAATCAATCAA

CRISPR arrays and Neighbor proteins around NC_008312_20

CRISPR arrays

The CRISPR arrays of NC_008312_20

>merge|NC_008312|20|2407713-2407829|CRISPRCasFinder
TTTATTATATATCGGGTCTATAAATAATTTTCTAGATTTCCTATTTTGAACATATTCTTTAGTCTTAGATCAATAATCAATCAATTTATTATATATCGGGCCTATAAATAATTTTCT

>NC_008312|20|17|2407713-2407829|CRISPRCasFinder
TTTATTATATATCGGGTCTATAAATAATTTTCT	AGATTTCCTATTTTGAACATATTCTTTAGTCTTAGATCAATAATCAATCAA
TTTATTATATATCGGGCCTATAAATAATTTTCT

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_008312.1|WP_011611239.1|2420397_2421585_+|alanine-racemase	unknown	unknown	gnl|CDD|234600
NC_008312.1|WP_044137251.1|2417921_2418425_-|phosphohistidine-phosphatase-SixA	unknown	unknown	gnl|CDD|224973
NC_008312.1|WP_011611233.1|2411650_2412274_-|NADH-quinone-oxidoreductase-subunit-J	unknown	unknown	gnl|CDD|214335
NC_008312.1|WP_044137246.1|2391935_2392334_-|DUF309-domain-containing-protein	unknown	unknown	gnl|CDD|377120
NC_008312.1|WP_044136555.1|2405481_2406150_+|hypothetical-protein	unknown	unknown	gnl|CDD|349951
NC_008312.1|WP_011611226.1|2399102_2400650_-|DNA-processing-protein-DprA	unknown	unknown	gnl|CDD|223829
NC_008312.1|WP_011611235.1|2415283_2416402_-|NADH-quinone-oxidoreductase-subunit-NuoH	unknown	unknown	gnl|CDD|214341
NC_008312.1|WP_011611223.1|2392916_2393282_-|ferredoxin--nitrite-reductase	unknown	unknown	gnl|CDD|214382
NC_008312.1|WP_011611231.1|2409950_2410151_-|hypothetical-protein	unknown	unknown	unknown
NC_008312.1|WP_011611236.1|2416672_2417824_-|citrate-synthase	unknown	unknown	gnl|CDD|237591
NC_008312.1|WP_011611228.1|2405020_2405527_+|pantetheine-phosphate-adenylyltransferase	unknown	unknown	gnl|CDD|234674
NC_008312.1|WP_044137249.1|2411298_2411610_-|NADH-quinone-oxidoreductase-subunit-NuoK	unknown	unknown	gnl|CDD|176958
NC_008312.1|WP_011611234.1|2412393_2413023_-|NAD(P)H-quinone-oxidoreductase-subunit-I	unknown	unknown	gnl|CDD|129498
NC_008312.1|WP_011611227.1|2402845_2404927_-|RecQ-family-ATP-dependent-DNA-helicase	unknown	unknown	gnl|CDD|223588
NC_008312.1|WP_011611220.1|2389694_2390372_+|dTMP-kinase	unknown	unknown	gnl|CDD|234814
NC_008312.1|WP_044136556.1|2419307_2419805_-|HNH-endonuclease	unknown	unknown	gnl|CDD|224321
NC_008312.1|WP_011611225.1|2397803_2398958_-|DUF58-domain-containing-protein	unknown	unknown	gnl|CDD|224635
NC_008312.1|WP_155994662.1|2422414_2422477_-|hypothetical-protein	unknown	unknown	unknown
NC_008312.1|WP_071820748.1|2390590_2391550_+|DNA-polymerase-III-subunit-delta'	unknown	unknown	gnl|CDD|236011
NC_008312.1|WP_011611224.1|2394704_2397167_+|SUMF1/EgtB/PvdO-family-nonheme-iron-enzyme	unknown	unknown	gnl|CDD|224182

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_008312.1|WP_011611239.1|2420397_2421585_+|alanine-racemase	gnl|CDD|234600	PRK00053, alr, alanine racemase; Reviewed.	0
NC_008312.1|WP_044137251.1|2417921_2418425_-|phosphohistidine-phosphatase-SixA	gnl|CDD|224973	COG2062, SixA, Phosphohistidine phosphatase SixA [Signal transduction mechanisms].	1.5587e-41
NC_008312.1|WP_011611233.1|2411650_2412274_-|NADH-quinone-oxidoreductase-subunit-J	gnl|CDD|214335	CHL00016, ndhG, NADH dehydrogenase subunit 6.	1.45405e-59
NC_008312.1|WP_044137246.1|2391935_2392334_-|DUF309-domain-containing-protein	gnl|CDD|377120	pfam03745, DUF309, Domain of unknown function (DUF309). This domain is found in eubacterial and archaebacterial proteins of unknown function. The proteins contain a motif HXXXEXX(W/Y) where X can be any amino acid. This motif is likely to be functionally important and may be involved in metal binding.	1.30551e-27
NC_008312.1|WP_044136555.1|2405481_2406150_+|hypothetical-protein	gnl|CDD|349951	cd06503, ATP-synt_Fo_b, F-type ATP synthase, membrane subunit b. Membrane subunit b is a component of the Fo complex of FoF1-ATP synthase. The F-type ATP synthases (FoF1-ATPase) consist of two structural domains: the F1 (assembly factor one) complex containing the soluble catalytic core, and the Fo (oligomycin sensitive factor) complex containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. F1 is composed of alpha (or A), beta (B), gamma (C), delta (D) and epsilon (E) subunits with a stoichiometry of 3:3:1:1:1, while Fo consists of the three subunits a, b, and c (1:2:10-14). An oligomeric ring of 10-14 c subunits (c-ring) make up the Fo rotor. The flux of protons through the ATPase channel (Fo) drives the rotation of the c-ring, which in turn is coupled to the rotation of the F1 complex gamma subunit rotor due to the permanent binding between the gamma and epsilon subunits of F1 and the c-ring of Fo. The F-ATP synthases are primarily found in the inner membranes of eukaryotic mitochondria, in the thylakoid membranes of chloroplasts or in the plasma membranes of bacteria. The F-ATP synthases are the primary producers of ATP, using the proton gradient generated by oxidative phosphorylation (mitochondria) or photosynthesis (chloroplasts). Alternatively, under conditions of low driving force, ATP synthases function as ATPases, thus generating a transmembrane proton or Na(+) gradient at the expense of energy derived from ATP hydrolysis. This group also includes F-ATP synthase that has also been found in the archaea Candidatus Methanoperedens.	0.000306783
NC_008312.1|WP_011611226.1|2399102_2400650_-|DNA-processing-protein-DprA	gnl|CDD|223829	COG0758, Smf, Predicted Rossmann fold nucleotide-binding protein involved in DNA uptake [DNA replication, recombination, and repair / Intracellular trafficking and secretion].	4.816e-47
NC_008312.1|WP_011611235.1|2415283_2416402_-|NADH-quinone-oxidoreductase-subunit-NuoH	gnl|CDD|214341	CHL00032, ndhA, NADH dehydrogenase subunit 1.	0
NC_008312.1|WP_011611223.1|2392916_2393282_-|ferredoxin--nitrite-reductase	gnl|CDD|214382	CHL00165, ftrB, ferredoxin thioreductase subunit beta; Validated.	1.78364e-63
NC_008312.1|WP_071820748.1|2390590_2391550_+|DNA-polymerase-III-subunit-delta'	gnl|CDD|236011	PRK07399, PRK07399, DNA polymerase III subunit delta'; Validated.	3.43085e-170
NC_008312.1|WP_011611236.1|2416672_2417824_-|citrate-synthase	gnl|CDD|237591	PRK14036, PRK14036, citrate synthase; Provisional.	0
NC_008312.1|WP_011611228.1|2405020_2405527_+|pantetheine-phosphate-adenylyltransferase	gnl|CDD|234674	PRK00168, coaD, phosphopantetheine adenylyltransferase; Provisional.	6.11788e-93
NC_008312.1|WP_044137249.1|2411298_2411610_-|NADH-quinone-oxidoreductase-subunit-NuoK	gnl|CDD|176958	CHL00015, ndhE, NADH dehydrogenase subunit 4L.	7.70058e-50
NC_008312.1|WP_011611234.1|2412393_2413023_-|NAD(P)H-quinone-oxidoreductase-subunit-I	gnl|CDD|129498	TIGR00403, NADPH-quinone_oxidoreductase_subunit_I, NADH-plastoquinone oxidoreductase subunit I protein. [Energy metabolism, Electron transport].	2.34453e-119
NC_008312.1|WP_011611227.1|2402845_2404927_-|RecQ-family-ATP-dependent-DNA-helicase	gnl|CDD|223588	COG0514, RecQ, Superfamily II DNA helicase [DNA replication, recombination, and repair].	8.44174e-147
NC_008312.1|WP_011611220.1|2389694_2390372_+|dTMP-kinase	gnl|CDD|234814	PRK00698, tmk, thymidylate kinase; Validated.	1.17775e-93
NC_008312.1|WP_044136556.1|2419307_2419805_-|HNH-endonuclease	gnl|CDD|224321	COG1403, McrA, Restriction endonuclease [Defense mechanisms].	2.6312e-32
NC_008312.1|WP_011611225.1|2397803_2398958_-|DUF58-domain-containing-protein	gnl|CDD|224635	COG1721, COG1721, Uncharacterized conserved protein (some members contain a von Willebrand factor type A (vWA) domain) [General function prediction only].	6.15916e-42
NC_008312.1|WP_011611224.1|2394704_2397167_+|SUMF1/EgtB/PvdO-family-nonheme-iron-enzyme	gnl|CDD|224182	COG1262, COG1262, Uncharacterized conserved protein [Function unknown].	2.05567e-80

Protein sequences

>NC_008312.1|WP_044136555.1|2405481_2406150_+|hypothetical-protein
MLRQNSAKANIEPEVNGQNVESQPASGSPGVDIQRELNRLEEIILDSPRIPFVGRTLIDEEQLLDQLDIVRLNLPVAFQEAEMIVRHKDDIFQEAELYAEEIIENAEQRASQILNEMGLVQQAKLEADQLRNQVQLDCEAIQQATITEIEQIRYQAQQELEEMRARAIAECDEIQNGADDYADHVLDSIEQQLTNMLQVIRNGRQQLGGDGTLGTPLNHTND
>NC_008312.1|WP_011611228.1|2405020_2405527_+|pantetheine-phosphate-adenylyltransferase
MIAIYPGSFDPITLGHIDIIERGCNLFEKVIVAVLRNQSKTSLFTIEQRLNQICHSTKHLLNVEVASFDGLAVNYAKMQQAKVLIRGLRVLSDFEKELQMAHTNKTLSPEIETVFLATSNEYSFLSSSVVKEIAVFGGSVDHLVPQHIAIDIYKCYDKTQPKPILNQR
>NC_008312.1|WP_011611227.1|2402845_2404927_-|RecQ-family-ATP-dependent-DNA-helicase
MIQKEALSLLRRALNNSTAEFRDGQWEAIAAITEHQSRLLVVQRTGWGKSFVYFLATRLLRDKGKGITLLISPLLALMRNQIAAAERIGIRAQTINSSNKEEWEKVENNLMVGKVDILLISPERLANENFRENILIYIAKNIGLFVVDEAHCISDWGHDFRPNYRRIARILQALPKNIPVLATTATANNRVVDDITVQLGANLKIFRGLLTRDSLQLQNIYLPSYCDRLGWLAEHLPNIPGSGIIYTLTVRDTEIVANWLKSQGINVAAYHSKKNTEEKEELEQQLLNNEIKALIATVALGMGFDKPDLGFVIHYQRPGSVVHYYQQVGRAGRAVENAYGILLSGEEDKEITNYFIKTAFPPEAHNQAILDALNQAEDGLSVPMLEEKLNLTNGQINKVLKLLSIETPSPIKKIQSKYYATPINYQTDTEKIARLNEIRHQEQDRMLDYMHSQECLMQFLRKELDDPNPSPCGKCAICLGKPLLPGNVSSKFVTEAVQFLRTREQIIETRKVWRKNALLTYNLTGKISKDLQAEIGRSLSIWNDAGWGQFVEKGKYKDNHFEDSLVQATYDMIQRWQPQPFPTWVTCIPSLTHPELVPNFAQRLAKKLGLPFVPCIIKIRQTSLQKDMTNSYQQAHNLDGAFKVYNWEGIRGNVFLVDDIVDSRWTFTVVAALLRNAGSGKVFPLALAINRFK
>NC_008312.1|WP_011611226.1|2399102_2400650_-|DNA-processing-protein-DprA
MLNHVLSSDAQVTLLLCASFGQNRNIQPQPLTLIEYNIVANFLIKNQVRPGYLLSKNGLDILPKINDKKLNYERLVALLERGGILAITLEKWVNQGLWVLTRSDQNYPIKWKQNLQYLAPVIIYGVGNIELLEKGGLAIVGSRDINEEEVEYTKKVGKVCASEGINVISGGAKGIDQEAMLGTLEFGGTAVGVLANSLNKASVSRKYRDSIRADKLTLISTYDPDAGFSVGNAMGRNKYIYALSDYALVVSSSFNKGGTWAGATEVLKKYKKIPVFVKVQGKVKEGNKALLDKGARSFPFDPWDGNLKDFLVGSKCDLKLSENISLIELETPVNISAKTANLNVETKSNLSIYEGTNPSIYEKVLPIILKNLIRPQKAKSLSKILDVRVGQLRNWLSQACDEEKIVKDEKTAIYRIVAETKQYQNYQISTEELNVYEMVLPILLDNLNKPQKIQDLAKILNVNKSQLEDWLKIAKTEGKIMLEKNSNVYVIYQDIKQLSLFDRVEDEDDEEGLDW
>NC_008312.1|WP_011611225.1|2397803_2398958_-|DUF58-domain-containing-protein
MKIYDKISDWLEINWVKPAYGGGLLGVLSIFFFAAAANTMAGWLYLISAITFALLGVSALLPGRSLREIKVRRDRIQPITVGDSLAIALTIENTTNKPLALLQVQDEIPFVLGKPVQQAIEVIPPKESYHWVYYLPTKKRGIYRWHYLQLRTAAPLGLFWCRRSRNAKATAIVYPTVLPLSRCPILDELGEEYSRQLHEHSRFEMASQGLTRTLRPYRFGDSSRLIHWRSSARYGELRVRELEVSKAGEEVLICLDSAAEWQPDNFEAAVTAAASLYFYANRSLLNVRLWTAATGLVYGNLAMLQTLAGVRFGEEVVVGNPPEKPLVWLTQNSLSLSSLPPGSRWLLWLDESVGYAAETPRMQYCSGLNISSDQPLEFQLQSSV
>NC_008312.1|WP_011611224.1|2394704_2397167_+|SUMF1/EgtB/PvdO-family-nonheme-iron-enzyme
MKYTIKFTMLLTTLTLVSCDKIPFMNKQLSQPEKLTFVAKKSGTPKNYSALNRLAQQTMVEIVSEGYLVGDDKYILKGSGVIIGRKDFVYYVLTANHIFNMNDIFYVFIRSKKLGKAGEVTGLKFINRYPQEDLALIAFASFTNYRVMELGDVSQLDDNNQVYVAGWPGYDNRENFQFTRAKVTNSQMGNNLTYKPIELENGLYKGMSGGAVLNEAGQLVGIHLGLTKVDEDREGVLISTFLRMVSPEVKDILERPTFLIILQAFVLLLLACFFFIVFDQYVYPWKKIWKKKKTSVAILPLPTREDQTITKFLIQNAESYFNQGLKYRNQRKYDLAIAEFNQAIKLNPKYAEAYYNRGNVYNTQGKYDLALVDYNQAIKFNPKYTQVYNNKGIIYNKQGKYDLALAEFNQAIKLNPKYSKVYNNRGIVYNNQRKYDLAIAEFNQAIKLNPKYAEAYYNRGNIYNNQGKYDLALAEFNQAIKFKPKYAKAYYNRGLVYKTQRNIERVISDFEKAAKLYKEQQNQRWYQNSLDKLKKLQYIYSEQEKSEKGQVFTFEVVRLNNSGNIISRTQGRAQQKIEHLGNDIKLEIVYIPGGSFLMGSPTEEVGRYSDEGPQHRVTLQPFYMSKYPITQDQYQVIMGNNPSRFRGGRCPVETVSWHDATEFCEKLSQKTGRDYRLPSESQWEYACRAGTTTPFYFGETITPDFANYYGNSSYGNGPKGKYRQQTTYVGIFPPNAFGLYDMHGNVWEWCADEWHDNYDGAPTDGSVWLDGNKNRSPLRGGSWVYCPYYCRSAIRSLFLPRDVHNYDFGFRVVCNSRRTF
>NC_008312.1|WP_011611223.1|2392916_2393282_-|ferredoxin--nitrite-reductase
MTLATEKKNLSSDKSLNAIKNFAERYAKKTNTYFCIDPSVTAVVIEGLAKHKEDLGAPLCPCRHYEDKQAEVKATYWNCPCVPMRERKECHCMLFLTPDNDFAGEQQEITQEDLESTRKNM
>NC_008312.1|WP_044137246.1|2391935_2392334_-|DUF309-domain-containing-protein
MTSKQEKIPQEFWQGIGEFNKQEFYKCHDILEALWLEAGEPERTFYQGILQIAVGLYHAGNENWRGSMMLLGEGISKLHYYQPSYFGINVDKLLIESCELLKYLQQSGQENLADFVRSHKNSKYPKILELKD
>NC_008312.1|WP_071820748.1|2390590_2391550_+|DNA-polymerase-III-subunit-delta'
MFDFINIIGQNQAIELLTQAMAHQRIAPAYLFAGPPGVGRALTAQCFIQLLFSHTNSFPPNSSSLKSRIQKRNHPDLLWLEPTYLHQGKLFSATEAAAAGVKRKSPPQIRLEQVRDIGQFLSRPPLQAARAVVVLQQAETMGENAANGLLKILEEPGKRATLILIAPGVDALLPTLVSRCQRIPFYRLTQENMKLVLEKVGYGKILDQPEVMEMAQGSPGEAIACWQQLQQIPADILEVATQGIRDIPQALTLARDISKSLDTEAQLWLIDYLQHCYWRQHPLIGVECLKHLEMARTYLLSYVQPRLVWECTLMAICSS
>NC_008312.1|WP_011611220.1|2389694_2390372_+|dTMP-kinase
MIGKFIVFEGVEGGGKTTQIELLQDWLLETGESRQILPKSIDLDLEVVITREPGGTKLGKALRELLLSPDVLAEKIQETSELLLYAADRAQHIEALIKPCLERGTIVLCDRFIDSTIAYQGYGRGLDVELIKQLNYIATGGLKSDLTFWLDIDVEIGLARAKSRGNFDRMEQANIEFHRRVQQGYQELAKNNSLIVRIDANLTREKVQQQIQAIIMQKLVEWKYI
>NC_008312.1|WP_011611231.1|2409950_2410151_-|hypothetical-protein
MNSEIKKYPSCSLHQDVSEYVADLQFHMTLHARNLVPSLNQIKDGREQMLQQTQAHFEKLISRQPL
>NC_008312.1|WP_044137249.1|2411298_2411610_-|NADH-quinone-oxidoreductase-subunit-NuoK
MQLQLEYFLLLAAALFCIGIYGLVTSRNAVRVLMSIELLLNAVNLNLMGFSNFLDSQNIKGQVFTVFVMTVAAAEAAVGLAIVLAIYRNRDTVDMEEFNLLKW
>NC_008312.1|WP_011611233.1|2411650_2412274_-|NADH-quinone-oxidoreductase-subunit-J
MDLAQGVQFVSFVILAVMMIAAALGVVLFSNIVHSAFLLGGVFMSISGLYLLLNADFVATAQVLIYVGAVNVLILFAIMLVNKREDFKALPNAWFRKVATGLVCFGLFALLSTMVLSSSWSIPVVGNATRESSIVLIGKHFFTDFLLPFELASVCLLIAMVGAIILARRDILPDEVPTNVSQTPVLSLPERPRELVSSLGESSAQIK
>NC_008312.1|WP_011611234.1|2412393_2413023_-|NAD(P)H-quinone-oxidoreductase-subunit-I
MFKFLKQVSDYAKETFQSAKYIGQGLSVTFDHMSRRPVTVQYPYEKLIPSERFRGRIHFEYDKCIACEVCVRVCPINLPVVDWEFNKETKKKKLKHYSIDFGVCIFCGNCVEYCPSNCLSMTEEYELAAYDRHELNYDNVALGRLPYKVTNDPMVTPMRELAYLPKGVIDPHTVPHTSRRAGLRPEEILEQIEAEKTAAEKTAAEITDK
>NC_008312.1|WP_011611235.1|2415283_2416402_-|NADH-quinone-oxidoreductase-subunit-NuoH
MNSGIDLQRTFIQALVDLGLSSEIAKTLWLPFPMLLMIVVATVGVLVTVWLERKISAAAQQRIGPEFMGPLGTLAPLADGLKLLFKEDVVPAKADPLLFTLGPVIVAVPVFLSYLVVPFGQNLVITDLGVAIFLWIALSSIQPIGLLMSGYASNNKYSLLGGLRAAAQSISYEIPLALAVLAVAMMSNSLSTIDIVEQQSSYGILGWNIWRQPLGFIIFWIAVLAECERLPFDLPEAEEELVAGYQTEYTGMKFALYYLASYVNLVLSSLLVAVLYLGGWESPLPVELISNWFGVSETTPWLQITNATLGIIMTLLKTYLLVFIAVLLRWTLPRVRIDQLLDLGWKFLLPVALVNLLLTAALKLTFPFAFGG
>NC_008312.1|WP_011611236.1|2416672_2417824_-|citrate-synthase
MSVVCIEFKPGLEGVPATQSSVSYVDGQKGILEYRGINIEELAKKSSFLEAAYLLIWGNLPTQEELQSFEQEICLNRRIKYRIRDMMKCFPETGHPMDALQTSAAALGLFYSRRALDNPEYIRKAVVRLLANIPTMVAAFELMRKGNDPVKPRDDLGYAANFLYMLNEREPDPLAAKVFDICLTLHAEHTINASTFSAMVTASTLTDPYGVIASAVGTLAGPLHGGANEDVISMLSEIGSVENVKPYLKRCFETKAKIAGFGHRVYKVKDPRAIILQELAVDLFEKFGDDKYYQIALEMEKVVEEKLGHKGIYPNVDFYSGLVYRKLGIPSDLFTPVFAIARVAGWLAHWKEQLAANRIFRPTQIYSGDHNIAYTSLEERALI
>NC_008312.1|WP_044137251.1|2417921_2418425_-|phosphohistidine-phosphatase-SixA
MMSTNVYFIRHGIAADRENYATDGERPLTEIGDRKTHKIAQKLKQLGLHFNLILTSPLVRANQTAKILQAHKLSSKVEEFSPLAPSGNINLWLQWLERWSPQSNKELAMVGHQPNLANWAEILIWGEVKQVLILKKAGIIGTSLPEIGSPVGNSQMFWLTPPRFILD
>NC_008312.1|WP_044136556.1|2419307_2419805_-|HNH-endonuclease
MANVLVLNASYEPLNITSWRRAIVLLLKGKAEQIEHKGIYLLPDIPLPTVIRLRYYIRVPYKDIPLTRRNVFHRDGHSCQYCGYMGDDLTLDHVIPRSRGGGDTWENLVTACVRCNVQKGSRTPKEANMILDCPPRKPRSGLYFELTKHVKSGMNKEWQKYVIGL
>NC_008312.1|WP_011611239.1|2420397_2421585_+|alanine-racemase
MLSREKTSFKTLALESDAYGGICQRAWVEINDRALSYNVQQLKSLLSAKTQLMGVVKADAYGHGASKISKTILEAGVDRLAVATLPEGIELRLAGIKPPILILGAIDRPEQIRAIAHWQLEPTICTPQQALVFSETLSYQTEPMLVHLKLDTGMSRLGTPWQQAVEFVKFVQGLPNLKIASIYSHLATADNLDQTVMKQQHQRFEEAIGLCGIGGKSFSSDIQLHLANSAATLTDPALHYDMVRVGLAIYGLYPAPHLQDKINLKPVMQVKARVTQVKTIEAGTGVSYGYQFIAPKQMRLAVVGIGYADGLPRNLSNRMKVIVRDRLIPQVGAITMDQLMLDVSAIPDLETGEVVTLLGQVGKHQISAENWANTLGTISWEILCGFKNRLPRVAV
>NC_008312.1|WP_155994662.1|2422414_2422477_-|hypothetical-protein
MPNSKKVATVLISTLNCKIT

Crispr_ID: NC_008312_21

• CRISPR_ID: NC_008312_21
• CRISPR_location: 2627134-2631455
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 85 spacers

Consensus repeat of NC_008312_21

Consensus_repeat	Method
NNTTTGAGGTTTNANGTT	CRT

spacers of NC_008312_21

>21.1|2627152|26|NC_008312|CRT
TTTGAGGTTTTAGGTTTGAAGTTTGA
>21.2|2627196|63|NC_008312|CRT
TTTTAGGTTTGAAGTTTGAGGTCTCAATTTTTTGAGGTTTGAGGTTTTAGGTTTTAGGTTTGA
>21.3|2627277|25|NC_008312|CRT
TTTGAGGTTTTAGTTTTAGGTTTGA
>21.4|2627320|47|NC_008312|CRT
TTTGAGGTGTTAGGTGTTAGGTGTTAGGTTTTAGGTTTTAGGTTTGA
>21.5|2627385|40|NC_008312|CRT
TTTGAGGTTTTAGGTTTTAGGCGTTAGGCGTTAGTTTTTA
>21.6|2627443|25|NC_008312|CRT
TTTGAGGTTTTAGGTTTTAGGTGTT
>21.7|2627486|25|NC_008312|CRT
TTACGTCTCAATTTTTTGAGGTGTT
>21.8|2627529|40|NC_008312|CRT
TTAAGTCTCATTTTTTTGAGGTTTTAGGTGTTAGGTGTTA
>21.9|2627587|19|NC_008312|CRT
TGAGGTCTCAATTTTTTGA
>21.10|2627624|26|NC_008312|CRT
TTAAGTTTGAGGTCTCAATTTTTTGA
>21.11|2627668|48|NC_008312|CRT
TGAGGTCTCAATTTTTTAAGGTTTTACGTTTTAAGCTTGAGGTCTCAA
>21.12|2627734|63|NC_008312|CRT
TTAAGTCTCATTTTTTTGAGGTTTTAGGTTTGAAGTTTGAAGTTTGAGGTCTCATTTTTTTGA
>21.13|2627815|46|NC_008312|CRT
TGAGGTTTGAGGTTTGAAGTTTGAGGTCTCATTTTTTTGAGGTTTT
>21.14|2627879|25|NC_008312|CRT
TTACATCTAAATTTTTTGAGGTTTT
>21.15|2627922|40|NC_008312|CRT
TGAGGTCTCAATTTTTTGAGGTTTGAGGTTTGAGGTTTGA
>21.16|2627980|63|NC_008312|CRT
TTAAGTCTCAATTTTTTGAGGTTTGAGGTTTGAAGTTTGAAGTTTTAAGTCTCAATTTTTTGA
>21.17|2628061|33|NC_008312|CRT
TGAGGTTTGAGGTCTCAATTTTTTGAGGCTTTA
>21.18|2628112|39|NC_008312|CRT
TCAATTTTTTGAGGTTTTAGTTTTAGGTTTGAAGTTTTA
>21.19|2628169|26|NC_008312|CRT
TCATTTTTTTGAGGTGTTAGGTTTTA
>21.20|2628213|19|NC_008312|CRT
TCAATTTTTTGAGGTTTTA
>21.21|2628250|26|NC_008312|CRT
TCATTTTTTTGAGGTGTTAGGTTTTA
>21.22|2628294|19|NC_008312|CRT
TCAATTTTTTGAGGCTTTA
>21.23|2628331|40|NC_008312|CRT
TCAATTTTTTGAGGTTTTAGGTGTTAGGTTTGAGGTTTGA
>21.24|2628389|25|NC_008312|CRT
TCATTTTTTTGAGGTTTTAGTTTTA
>21.25|2628432|25|NC_008312|CRT
TCAATTTTTTGAGGTTTTAGTTTTA
>21.26|2628475|19|NC_008312|CRT
TCAATTTTTTGAGGTTTTA
>21.27|2628512|19|NC_008312|CRT
TCAATTTTTTGAGGTTTGA
>21.28|2628549|25|NC_008312|CRT
TCATTTTTTTGAGGTTTTAGTTTTA
>21.29|2628592|19|NC_008312|CRT
TCAATTTTTTGAGGTTTGA
>21.30|2628629|19|NC_008312|CRT
TGAGGTCTCATTTTTTTGA
>21.31|2628666|26|NC_008312|CRT
TTAAGTCTCAATTTTTTGAGGCTTTA
>21.32|2628710|26|NC_008312|CRT
TCAATTTTTTGAGGTTTTAGGTGTTA
>21.33|2628754|19|NC_008312|CRT
TGAAGTTTGAGGTCTCATT
>21.34|2628791|25|NC_008312|CRT
TAGGTTTTAAGTTTTACATCTCAAT
>21.35|2628834|25|NC_008312|CRT
TAGGTTTGAAGTTTGAGGTCTCATT
>21.36|2628877|40|NC_008312|CRT
TGAGGTTTGAGGTTTTAGGTTTGAAGTTTTAAGTCTCAAT
>21.37|2628935|26|NC_008312|CRT
TGAAGTTTGAAGTTTTAAGTCTCAAT
>21.38|2628979|26|NC_008312|CRT
TGAAGTTTGAGGTTTGAGGTCTCAAT
>21.39|2629023|19|NC_008312|CRT
TGAAGTTTTAAGTCTCAAT
>21.40|2629060|40|NC_008312|CRT
TTAGGTTTGAGGTTTTAGGTTTGAAGTTTGAGGTCTCATT
>21.41|2629118|25|NC_008312|CRT
TAGGTTTGAAGTTTTAAGTCTCAAT
>21.42|2629161|26|NC_008312|CRT
TGAAGTTTGAGGTTTGAGGTCTCAAT
>21.43|2629205|19|NC_008312|CRT
TGAAGTTTTAAGTCTCAAT
>21.44|2629242|40|NC_008312|CRT
TTAGGTTTGAGGTTTGAGGTTTGAAGTTTGAGGTCTCATT
>21.45|2629300|25|NC_008312|CRT
TAGGTTTGAAGTTTTAAGTCTCAAT
>21.46|2629343|62|NC_008312|CRT
TAGGTTTGAAGTTTTAAGTCTCAATTTTTTGAGGTTTTAGGTTTGAAGTTTGAGGTCTCAAT
>21.47|2629423|55|NC_008312|CRT
TAGGTTTGAAGTTTTAGGTTTGAAGTTTTAAGTCTCAATTTTTTGAGGTCTCATT
>21.48|2629496|62|NC_008312|CRT
TGAAGTTTGAGGTCTCAATTTTTTGAGGTTTTAGTTTTAGGTTTTAAGTTTTACATCTCAAT
>21.49|2629576|62|NC_008312|CRT
TAGGTTTCAAGTTTGAGGTCTCAATTTTTTGAGGTTTTAAGTTTTAAGTTTGAGGTCTCAAT
>21.50|2629656|62|NC_008312|CRT
TTAAGTTTGAGGTCTCAATTTTTTGATGTTTGAGTTTTAGGTTTGAAGTTTTAAGTCTCAAT
>21.51|2629736|40|NC_008312|CRT
TTAGGTTTTAGGTTTTAGGTTTTAAGTTTGAGGTCTCATT
>21.52|2629794|40|NC_008312|CRT
TTAAGCTTGAGGTTTTAGGTTTGAAGTTTGAGGTCTCATT
>21.53|2629852|48|NC_008312|CRT
TTAAGCTTGAGGTCTCAAGGTTTGAGGTTTTAAGTTTTAAGTCTCATT
>21.54|2629918|63|NC_008312|CRT
TGAAGTTTGAAGTTTGAGGTCTCATTTTTTTGAGGTTTGAAGTTTGAAGTTTGAGGTCTCATT
>21.55|2629999|25|NC_008312|CRT
TAGGTTTTAAGTTTTACATCTCAAT
>21.56|2630042|25|NC_008312|CRT
TAGGTTTGAAGTTTGAGGTCTCAAT
>21.57|2630085|47|NC_008312|CRT
TGAGGTTTGAGGTTTTAGGTTTTAGGTTTGAAGTTTTAAGTCTCAAT
>21.58|2630150|26|NC_008312|CRT
TGAAGTTTGAAGTTTGAGGTCTCAAT
>21.59|2630194|19|NC_008312|CRT
TGAAGTTTTAAGTCTCATT
>21.60|2630231|39|NC_008312|CRT
GAGGTTTGAGGTTTTAGGTTTGAAGTTTGAGGTCTCATT
>21.61|2630288|25|NC_008312|CRT
GAGGTTTGAAGTTTGAGGTCTCATT
>21.62|2630331|25|NC_008312|CRT
GAGGTTTGAAGTTTGAGGTCTCATT
>21.63|2630374|26|NC_008312|CRT
TGAAGTTTGAAGTTTTAAGTCTCAAT
>21.64|2630418|19|NC_008312|CRT
TGAAGTTTGAGGTCTCATT
>21.65|2630455|39|NC_008312|CRT
GAGGTTTGAGGTTTTAGGTTTGAAGTTTGAGGTCTCATT
>21.66|2630512|39|NC_008312|CRT
TTAGGTGTTAGTTTTAGGTTTGAAGTTTGAGGTCTCATT
>21.67|2630569|26|NC_008312|CRT
TGAAGTTTGAAGTTTGAGGTCTCATT
>21.68|2630613|40|NC_008312|CRT
TGAAGTTTGAGGTTTTAGGTTTGAAGTTTGAGGTCTCATT
>21.69|2630671|26|NC_008312|CRT
TGAGGTTTGAAGTTTTAAGTCTCATT
>21.70|2630715|26|NC_008312|CRT
TGAAGTTTGAAGTTTGAGGTCTCATT
>21.71|2630759|19|NC_008312|CRT
TGAAGTTTGAGGTCTCATT
>21.72|2630796|39|NC_008312|CRT
TAGGTTTGAGGTTTTAGGTTTGAAGTTTGAGGTCTCATT
>21.73|2630853|39|NC_008312|CRT
TAGGTGTTAGGTTTTAGGTTTGAAGTTTGAGGTCTCATT
>21.74|2630910|26|NC_008312|CRT
TTAGGTTTTAAGTTTTAAGTCTCATT
>21.75|2630954|26|NC_008312|CRT
TGAAGTTTGAAGTTTGAGGTCTCATT
>21.76|2630998|19|NC_008312|CRT
TGAAGTTTGAGGTCTCATT
>21.77|2631035|25|NC_008312|CRT
TAGGTTTTAAGTTTGAGGTATCAAT
>21.78|2631078|25|NC_008312|CRT
TAGGTTTGAAGTTTGAGGTCTCAAT
>21.79|2631121|19|NC_008312|CRT
TGAAGTTTTAAGTCTCAAT
>21.80|2631158|26|NC_008312|CRT
TGAAGTTTGAAGTTTTAAGTCTCAAT
>21.81|2631202|26|NC_008312|CRT
TTAAGCTTTAAGTTTGAGGTCTCATT
>21.82|2631246|39|NC_008312|CRT
TAGGTGTTAGGTTTGAGGTTTTAAGTTTGAGGTCTCAAT
>21.83|2631303|19|NC_008312|CRT
TTAAGTTTGAGGTCTCAAT
>21.84|2631340|40|NC_008312|CRT
TGAAGTTTTAGGTGTTAGTTTTGAAGTTTGAGGTCTCAAT
>21.85|2631398|40|NC_008312|CRT
TTAGGTTTTAGGTGTTAGTTTTGAAGTTTGAGGTATCAAT

CRISPR arrays and Neighbor proteins around NC_008312_21

CRISPR arrays

The CRISPR arrays of NC_008312_21

>merge|NC_008312|21|2627134-2631455|CRT
AGTTTTAAGTCTCAATTTTTTGAGGTTTTAGGTTTGAAGTTTGAAGTTTGAGGTCTCAATTTTTTTAGGTTTGAAGTTTGAGGTCTCAATTTTTTGAGGTTTGAGGTTTTAGGTTTTAGGTTTGAAGTTTGAGGTCTCATTTTTTTGAGGTTTTAGTTTTAGGTTTGAAGTTTTACGTCTCAATTTTTTGAGGTGTTAGGTGTTAGGTGTTAGGTTTTAGGTTTTAGGTTTGAAGTTTTAAGTCTCAATTTTTTGAGGTTTTAGGTTTTAGGCGTTAGGCGTTAGTTTTTAAGTTTGAGGTCTCAATTTTTTGAGGTTTTAGGTTTTAGGTGTTAGTTTTAGGTTTGAAGTTTTACGTCTCAATTTTTTGAGGTGTTAGTTTTAGGTTTGAAGTTTTAAGTCTCATTTTTTTGAGGTTTTAGGTGTTAGGTGTTAGGTGTTAGGTTTGAAGTTTGAGGTCTCAATTTTTTGAGGTGTTAGGTTTTAAGTTTTAAGTTTGAGGTCTCAATTTTTTGAGGTTTTAAGTTTTAAGTTTGAGGTCTCAATTTTTTAAGGTTTTACGTTTTAAGCTTGAGGTCTCAAGGTTTGAGGTTTTAAGTTTTAAGTCTCATTTTTTTGAGGTTTTAGGTTTGAAGTTTGAAGTTTGAGGTCTCATTTTTTTGAGGTTTTAGGTTTTAGGTTTGAGGTTTGAGGTTTGAAGTTTGAGGTCTCATTTTTTTGAGGTTTTAGTTTTAGGTTTTAAGTTTTACATCTAAATTTTTTGAGGTTTTAGTTTTAGGTTTGAAGTTTGAGGTCTCAATTTTTTGAGGTTTGAGGTTTGAGGTTTGAGGTTTTAGGTTTGAAGTTTTAAGTCTCAATTTTTTGAGGTTTGAGGTTTGAAGTTTGAAGTTTTAAGTCTCAATTTTTTGAGGTGTTAGGTTTTAAGTTTGAGGTTTGAGGTCTCAATTTTTTGAGGCTTTAGGTTTGAAGTTTTAAGTCTCAATTTTTTGAGGTTTTAGTTTTAGGTTTGAAGTTTTAGGTTTGAAGTTTGAGGTCTCATTTTTTTGAGGTGTTAGGTTTTAAGTTTGAAGTTTGAGGTCTCAATTTTTTGAGGTTTTAGGTTTGAAGTTTGAGGTCTCATTTTTTTGAGGTGTTAGGTTTTAATTTTGAAGTTTTAAGTCTCAATTTTTTGAGGCTTTAGGTTTGAAGTTTTAAGTCTCAATTTTTTGAGGTTTTAGGTGTTAGGTTTGAGGTTTGAGGTTTGAAGTTTGAGGTCTCATTTTTTTGAGGTTTTAGTTTTAGGTTTGAAGTTTGAGGTCTCAATTTTTTGAGGTTTTAGTTTTAGGTTTGAAGTTTTAAGTCTCAATTTTTTGAGGTTTTAGGTTTGAAGTTTGAGGTCTCAATTTTTTGAGGTTTGAGGTTTGAAGTTTGAGGTCTCATTTTTTTGAGGTTTTAGTTTTAGGTTTGAAGTTTTAAGTCTCAATTTTTTGAGGTTTGAGGTTTGAAGTTTGAAGTTTGAGGTCTCATTTTTTTGAGGTTTGAAGTTTGAAGTTTTAAGTCTCAATTTTTTGAGGCTTTAGGTTTGAAGTTTTAAGTCTCAATTTTTTGAGGTTTTAGGTGTTAGGTTTGAGGTTTGAGGTTTGAAGTTTGAGGTCTCATTTTTTTGAGGTTTTAGTTTTAGGTTTTAAGTTTTACATCTCAATTTTTTGAGGTTTTAGTTTTAGGTTTGAAGTTTGAGGTCTCATTTTTTTGAGGTTTGAGGTTTGAGGTTTGAGGTTTTAGGTTTGAAGTTTTAAGTCTCAATTTTTTGAGGTTTTAGGTTTGAAGTTTGAAGTTTTAAGTCTCAATTTTTTGAGGTGTTAGGTTTGAAGTTTGAGGTTTGAGGTCTCAATTTTTTGAGGCTTTAGGTTTGAAGTTTTAAGTCTCAATTTTTTCAGGTTTTAGGTGTTAGGTTTGAGGTTTTAGGTTTGAAGTTTGAGGTCTCATTTTTTTGAGGTTTTAGTTTTAGGTTTGAAGTTTTAAGTCTCAATTTTTTGAGGTGTTAGGTTTGAAGTTTGAGGTTTGAGGTCTCAATTTTTTGAGGTTTTAGGTTTGAAGTTTTAAGTCTCAATTTTTTCAGGTTTTAGGTGTTAGGTTTGAGGTTTGAGGTTTGAAGTTTGAGGTCTCATTTTTTTGAGGTTTTAGTTTTAGGTTTGAAGTTTTAAGTCTCAATTTTTTGAGGTTTTAGTTTTAGGTTTGAAGTTTTAAGTCTCAATTTTTTGAGGTTTTAGGTTTGAAGTTTGAGGTCTCAATTTTTTGAGGTTTTAGTTTTAGGTTTGAAGTTTTAGGTTTGAAGTTTTAAGTCTCAATTTTTTGAGGTCTCATTTTTTTGAGGTTTTAGGTTTGAAGTTTGAGGTCTCAATTTTTTGAGGTTTTAGTTTTAGGTTTTAAGTTTTACATCTCAATTTTTTGAGGTTTTAGTTTTAGGTTTCAAGTTTGAGGTCTCAATTTTTTGAGGTTTTAAGTTTTAAGTTTGAGGTCTCAATTTTTTGAGGTTTTAGGTTTTAAGTTTGAGGTCTCAATTTTTTGATGTTTGAGTTTTAGGTTTGAAGTTTTAAGTCTCAATTTTTTGAGGTTTTAGGTGTTAGGTTTTAGGTTTTAGGTTTTAAGTTTGAGGTCTCATTTTTTTGAGGTTTTACGTTTTAAGCTTGAGGTTTTAGGTTTGAAGTTTGAGGTCTCATTTTTTTGAGGTTTTACGTTTTAAGCTTGAGGTCTCAAGGTTTGAGGTTTTAAGTTTTAAGTCTCATTTTTTTGAGGTTTTAGGTTTGAAGTTTGAAGTTTGAGGTCTCATTTTTTTGAGGTTTGAAGTTTGAAGTTTGAGGTCTCATTTTTTTGAGGTTTTAGTTTTAGGTTTTAAGTTTTACATCTCAATTTTTTGAGGTTTTAGTTTTAGGTTTGAAGTTTGAGGTCTCAATTTTTTGAGGTTTGAGGTTTGAGGTTTGAGGTTTTAGGTTTTAGGTTTGAAGTTTTAAGTCTCAATTTTTTGAGGTTTTAGGTTTGAAGTTTGAAGTTTGAGGTCTCAATTTTTTGAGGCTTTAGGTTTGAAGTTTTAAGTCTCATTTTTTTGAGGTTTTAGTTTGAGGTTTGAGGTTTTAGGTTTGAAGTTTGAGGTCTCATTTTTTTGAGGTTTTAGTTTGAGGTTTGAAGTTTGAGGTCTCATTTTTTTGAGGTTTTAGTTTGAGGTTTGAAGTTTGAGGTCTCATTTTTTTGAGGTTTGAGGTTTGAAGTTTGAAGTTTTAAGTCTCAATTTTTTGAGGTTTGAAGTTTGAAGTTTGAGGTCTCATTTTTTTGAGGTTTTAGTTTGAGGTTTGAGGTTTTAGGTTTGAAGTTTGAGGTCTCATTTTTTTGAGGTTTTAGGTTTTAGGTGTTAGTTTTAGGTTTGAAGTTTGAGGTCTCATTTTTTTGAGGTTTTAGGTTTGAAGTTTGAAGTTTGAGGTCTCATTTTTTTGAGGTTTGAAGTTTGAAGTTTGAGGTTTTAGGTTTGAAGTTTGAGGTCTCATTTTTTTGAGGTTTTAGGTTTGAGGTTTGAAGTTTTAAGTCTCATTTTTTTGAGGTTTTAGGTTTGAAGTTTGAAGTTTGAGGTCTCATTTTTTTGAGGTTTTAGGTTTGAAGTTTGAGGTCTCATTTTTTTGAGGTTTTAGTTTTAGGTTTGAGGTTTTAGGTTTGAAGTTTGAGGTCTCATTTTTTTGAGGTGTTAGTTTTAGGTGTTAGGTTTTAGGTTTGAAGTTTGAGGTCTCATTTTTTTGAGGTTTTAGGTTTTAGGTTTTAAGTTTTAAGTCTCATTTTTTTGAGGTTTTAGGTTTGAAGTTTGAAGTTTGAGGTCTCATTTTTTTGAGGTTTGAAGTTTGAAGTTTGAGGTCTCATTTTTTTGAGGTTTTAGTTTTAGGTTTTAAGTTTGAGGTATCAATTTTTTGAGGTTTTAGTTTTAGGTTTGAAGTTTGAGGTCTCAATTTTTTGAGGTTTGAAGTTTGAAGTTTTAAGTCTCAATTTTTTGAGGTTTTACGTTTGAAGTTTGAAGTTTTAAGTCTCAATTTTTTGAGGTTTTACGTTTTAAGCTTTAAGTTTGAGGTCTCATTTTTTTGAGGTGTTAGTTTTAGGTGTTAGGTTTGAGGTTTTAAGTTTGAGGTCTCAATTTTTTGAGGTTTTAAGTTTTAAGTTTGAGGTCTCAATTTTTTGAGGTTTTAGGTTTGAAGTTTTAGGTGTTAGTTTTGAAGTTTGAGGTCTCAATTTTTTGAGGTTTTAGGTGTTAGGTTTTAGGTGTTAGTTTTGAAGTTTGAGGTATCAATTTTTTGAGGTTTTAGGTG

>NC_008312|21|5|2627134-2631455|CRT
AGTTTTAAGTCTCAATTT	TTTGAGGTTTTAGGTTTGAAGTTTGA
AGTTTGAGGTCTCAATTT	TTTTAGGTTTGAAGTTTGAGGTCTCAATTTTTTGAGGTTTGAGGTTTTAGGTTTTAGGTTTGA
AGTTTGAGGTCTCATTTT	TTTGAGGTTTTAGTTTTAGGTTTGA
AGTTTTACGTCTCAATTT	TTTGAGGTGTTAGGTGTTAGGTGTTAGGTTTTAGGTTTTAGGTTTGA
AGTTTTAAGTCTCAATTT	TTTGAGGTTTTAGGTTTTAGGCGTTAGGCGTTAGTTTTTA
AGTTTGAGGTCTCAATTT	TTTGAGGTTTTAGGTTTTAGGTGTT
AGTTTTAGGTTTGAAGTT	TTACGTCTCAATTTTTTGAGGTGTT
AGTTTTAGGTTTGAAGTT	TTAAGTCTCATTTTTTTGAGGTTTTAGGTGTTAGGTGTTA
GGTGTTAGGTTTGAAGTT	TGAGGTCTCAATTTTTTGA
GGTGTTAGGTTTTAAGTT	TTAAGTTTGAGGTCTCAATTTTTTGA
GGTTTTAAGTTTTAAGTT	TGAGGTCTCAATTTTTTAAGGTTTTACGTTTTAAGCTTGAGGTCTCAA
GGTTTGAGGTTTTAAGTT	TTAAGTCTCATTTTTTTGAGGTTTTAGGTTTGAAGTTTGAAGTTTGAGGTCTCATTTTTTTGA
GGTTTTAGGTTTTAGGTT	TGAGGTTTGAGGTTTGAAGTTTGAGGTCTCATTTTTTTGAGGTTTT
AGTTTTAGGTTTTAAGTT	TTACATCTAAATTTTTTGAGGTTTT
AGTTTTAGGTTTGAAGTT	TGAGGTCTCAATTTTTTGAGGTTTGAGGTTTGAGGTTTGA
GGTTTTAGGTTTGAAGTT	TTAAGTCTCAATTTTTTGAGGTTTGAGGTTTGAAGTTTGAAGTTTTAAGTCTCAATTTTTTGA
GGTGTTAGGTTTTAAGTT	TGAGGTTTGAGGTCTCAATTTTTTGAGGCTTTA
GGTTTGAAGTTTTAAGTC	TCAATTTTTTGAGGTTTTAGTTTTAGGTTTGAAGTTTTA
GGTTTGAAGTTTGAGGTC	TCATTTTTTTGAGGTGTTAGGTTTTA
AGTTTGAAGTTTGAGGTC	TCAATTTTTTGAGGTTTTA
GGTTTGAAGTTTGAGGTC	TCATTTTTTTGAGGTGTTAGGTTTTA
ATTTTGAAGTTTTAAGTC	TCAATTTTTTGAGGCTTTA
GGTTTGAAGTTTTAAGTC	TCAATTTTTTGAGGTTTTAGGTGTTAGGTTTGAGGTTTGA
GGTTTGAAGTTTGAGGTC	TCATTTTTTTGAGGTTTTAGTTTTA
GGTTTGAAGTTTGAGGTC	TCAATTTTTTGAGGTTTTAGTTTTA
GGTTTGAAGTTTTAAGTC	TCAATTTTTTGAGGTTTTA
GGTTTGAAGTTTGAGGTC	TCAATTTTTTGAGGTTTGA
GGTTTGAAGTTTGAGGTC	TCATTTTTTTGAGGTTTTAGTTTTA
GGTTTGAAGTTTTAAGTC	TCAATTTTTTGAGGTTTGA
GGTTTGAAGTTTGAAGTT	TGAGGTCTCATTTTTTTGA
GGTTTGAAGTTTGAAGTT	TTAAGTCTCAATTTTTTGAGGCTTTA
GGTTTGAAGTTTTAAGTC	TCAATTTTTTGAGGTTTTAGGTGTTA
GGTTTGAGGTTTGAGGTT	TGAAGTTTGAGGTCTCATT
TTTTTGAGGTTTTAGTTT	TAGGTTTTAAGTTTTACATCTCAAT
TTTTTGAGGTTTTAGTTT	TAGGTTTGAAGTTTGAGGTCTCATT
TTTTTGAGGTTTGAGGTT	TGAGGTTTGAGGTTTTAGGTTTGAAGTTTTAAGTCTCAAT
TTTTTGAGGTTTTAGGTT	TGAAGTTTGAAGTTTTAAGTCTCAAT
TTTTTGAGGTGTTAGGTT	TGAAGTTTGAGGTTTGAGGTCTCAAT
TTTTTGAGGCTTTAGGTT	TGAAGTTTTAAGTCTCAAT
TTTTTCAGGTTTTAGGTG	TTAGGTTTGAGGTTTTAGGTTTGAAGTTTGAGGTCTCATT
TTTTTGAGGTTTTAGTTT	TAGGTTTGAAGTTTTAAGTCTCAAT
TTTTTGAGGTGTTAGGTT	TGAAGTTTGAGGTTTGAGGTCTCAAT
TTTTTGAGGTTTTAGGTT	TGAAGTTTTAAGTCTCAAT
TTTTTCAGGTTTTAGGTG	TTAGGTTTGAGGTTTGAGGTTTGAAGTTTGAGGTCTCATT
TTTTTGAGGTTTTAGTTT	TAGGTTTGAAGTTTTAAGTCTCAAT
TTTTTGAGGTTTTAGTTT	TAGGTTTGAAGTTTTAAGTCTCAATTTTTTGAGGTTTTAGGTTTGAAGTTTGAGGTCTCAAT
TTTTTGAGGTTTTAGTTT	TAGGTTTGAAGTTTTAGGTTTGAAGTTTTAAGTCTCAATTTTTTGAGGTCTCATT
TTTTTGAGGTTTTAGGTT	TGAAGTTTGAGGTCTCAATTTTTTGAGGTTTTAGTTTTAGGTTTTAAGTTTTACATCTCAAT
TTTTTGAGGTTTTAGTTT	TAGGTTTCAAGTTTGAGGTCTCAATTTTTTGAGGTTTTAAGTTTTAAGTTTGAGGTCTCAAT
TTTTTGAGGTTTTAGGTT	TTAAGTTTGAGGTCTCAATTTTTTGATGTTTGAGTTTTAGGTTTGAAGTTTTAAGTCTCAAT
TTTTTGAGGTTTTAGGTG	TTAGGTTTTAGGTTTTAGGTTTTAAGTTTGAGGTCTCATT
TTTTTGAGGTTTTACGTT	TTAAGCTTGAGGTTTTAGGTTTGAAGTTTGAGGTCTCATT
TTTTTGAGGTTTTACGTT	TTAAGCTTGAGGTCTCAAGGTTTGAGGTTTTAAGTTTTAAGTCTCATT
TTTTTGAGGTTTTAGGTT	TGAAGTTTGAAGTTTGAGGTCTCATTTTTTTGAGGTTTGAAGTTTGAAGTTTGAGGTCTCATT
TTTTTGAGGTTTTAGTTT	TAGGTTTTAAGTTTTACATCTCAAT
TTTTTGAGGTTTTAGTTT	TAGGTTTGAAGTTTGAGGTCTCAAT
TTTTTGAGGTTTGAGGTT	TGAGGTTTGAGGTTTTAGGTTTTAGGTTTGAAGTTTTAAGTCTCAAT
TTTTTGAGGTTTTAGGTT	TGAAGTTTGAAGTTTGAGGTCTCAAT
TTTTTGAGGCTTTAGGTT	TGAAGTTTTAAGTCTCATT
TTTTTGAGGTTTTAGTTT	GAGGTTTGAGGTTTTAGGTTTGAAGTTTGAGGTCTCATT
TTTTTGAGGTTTTAGTTT	GAGGTTTGAAGTTTGAGGTCTCATT
TTTTTGAGGTTTTAGTTT	GAGGTTTGAAGTTTGAGGTCTCATT
TTTTTGAGGTTTGAGGTT	TGAAGTTTGAAGTTTTAAGTCTCAAT
TTTTTGAGGTTTGAAGTT	TGAAGTTTGAGGTCTCATT
TTTTTGAGGTTTTAGTTT	GAGGTTTGAGGTTTTAGGTTTGAAGTTTGAGGTCTCATT
TTTTTGAGGTTTTAGGTT	TTAGGTGTTAGTTTTAGGTTTGAAGTTTGAGGTCTCATT
TTTTTGAGGTTTTAGGTT	TGAAGTTTGAAGTTTGAGGTCTCATT
TTTTTGAGGTTTGAAGTT	TGAAGTTTGAGGTTTTAGGTTTGAAGTTTGAGGTCTCATT
TTTTTGAGGTTTTAGGTT	TGAGGTTTGAAGTTTTAAGTCTCATT
TTTTTGAGGTTTTAGGTT	TGAAGTTTGAAGTTTGAGGTCTCATT
TTTTTGAGGTTTTAGGTT	TGAAGTTTGAGGTCTCATT
TTTTTGAGGTTTTAGTTT	TAGGTTTGAGGTTTTAGGTTTGAAGTTTGAGGTCTCATT
TTTTTGAGGTGTTAGTTT	TAGGTGTTAGGTTTTAGGTTTGAAGTTTGAGGTCTCATT
TTTTTGAGGTTTTAGGTT	TTAGGTTTTAAGTTTTAAGTCTCATT
TTTTTGAGGTTTTAGGTT	TGAAGTTTGAAGTTTGAGGTCTCATT
TTTTTGAGGTTTGAAGTT	TGAAGTTTGAGGTCTCATT
TTTTTGAGGTTTTAGTTT	TAGGTTTTAAGTTTGAGGTATCAAT
TTTTTGAGGTTTTAGTTT	TAGGTTTGAAGTTTGAGGTCTCAAT
TTTTTGAGGTTTGAAGTT	TGAAGTTTTAAGTCTCAAT
TTTTTGAGGTTTTACGTT	TGAAGTTTGAAGTTTTAAGTCTCAAT
TTTTTGAGGTTTTACGTT	TTAAGCTTTAAGTTTGAGGTCTCATT
TTTTTGAGGTGTTAGTTT	TAGGTGTTAGGTTTGAGGTTTTAAGTTTGAGGTCTCAAT
TTTTTGAGGTTTTAAGTT	TTAAGTTTGAGGTCTCAAT
TTTTTGAGGTTTTAGGTT	TGAAGTTTTAGGTGTTAGTTTTGAAGTTTGAGGTCTCAAT
TTTTTGAGGTTTTAGGTG	TTAGGTTTTAGGTGTTAGTTTTGAAGTTTGAGGTATCAAT
TTTTTGAGGTTTTAGGTG

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_008312.1|WP_011611372.1|2640870_2641221_-|hypothetical-protein	unknown	unknown	unknown
NC_008312.1|WP_155994364.1|2616707_2616857_-|hypothetical-protein	unknown	unknown	gnl|CDD|376876
NC_008312.1|WP_081432419.1|2613496_2613754_-|hypothetical-protein	unknown	unknown	gnl|CDD|366375
NC_008312.1|WP_155994366.1|2641514_2641664_-|hypothetical-protein	unknown	unknown	unknown
NC_008312.1|WP_011611368.1|2634406_2637040_-|formylglycine-generating-enzyme-family-protein	unknown	unknown	gnl|CDD|224182
NC_008312.1|WP_081432534.1|2626613_2626817_-|hypothetical-protein	unknown	unknown	gnl|CDD|368559
NC_008312.1|WP_155994365.1|2632599_2632785_+|hypothetical-protein	unknown	unknown	unknown
NC_008312.1|WP_155994669.1|2611092_2613351_-|tetratricopeptide-repeat-protein	unknown	unknown	gnl|CDD|274350
NC_008312.1|WP_011611363.1|2623271_2624444_+|DNA-replication/repair-protein-RecF	unknown	unknown	gnl|CDD|234608
NC_008312.1|WP_011611364.1|2624875_2625889_+|hypothetical-protein	unknown	unknown	unknown
NC_008312.1|WP_011611370.1|2638092_2640024_-|trypsin-like-peptidase-domain-containing-protein	unknown	unknown	gnl|CDD|379142
NC_008312.1|WP_011611362.1|2621231_2622833_+|B12-binding-domain-containing-radical-SAM-protein	unknown	unknown	gnl|CDD|379101
NC_008312.1|WP_044136583.1|2631604_2632483_-|formylglycine-generating-enzyme-family-protein	unknown	unknown	gnl|CDD|224182
NC_008312.1|WP_011611361.1|2618664_2620149_-|protein-kinase	unknown	unknown	gnl|CDD|319862
NC_008312.1|WP_011611369.1|2637043_2638096_-|AAA-family-ATPase	unknown	unknown	gnl|CDD|223786
NC_008312.1|WP_011611360.1|2617043_2618561_-|protein-kinase	unknown	unknown	gnl|CDD|319862
NC_008312.1|WP_044137279.1|2640086_2640437_-|hypothetical-protein	unknown	unknown	unknown
NC_008312.1|WP_011611367.1|2633968_2634310_-|diversity-generating-retroelement-protein-Avd	unknown	unknown	gnl|CDD|380307
NC_008312.1|WP_052845770.1|2616547_2616751_-|DUF192-domain-containing-protein	unknown	unknown	gnl|CDD|376876
NC_008312.1|WP_011611373.1|2643844_2645032_-|glycosyltransferase-family-4-protein	unknown	unknown	gnl|CDD|340831

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_008312.1|WP_155994364.1|2616707_2616857_-|hypothetical-protein	gnl|CDD|376876	pfam02643, DUF192, Uncharacterized ACR, COG1430. Two structures have been solved for members of this large (>500 members) family of bacterial proteins present mostly in environmental bacteria and metagenomes (distant homologs are also present in several Plasmodium species). TOPSAN analysis for Structure 3pjy shows that there is much similarity with the other solved structure, Structure 3m7a, solved for UniProt:Q2GA55 (Saro_0823), a homolog of Thermotoga maritima TM1668, UniProt:Q9X1Z6., The homolog in Caulobacter crescentus (CC1388), UniProt:Q9A8G6, is associated with CspD, a cold shock protein (CC1387), UniProt:Q9A8G7. However, the genomic context of UniProt:Q2GA55 is most conserved with a putative xylose isomerase, suggesting a possible role in extracellular sugar processing. Saro_0821, UniProt:Q2GA57, is annotated as an AMP-dependent synthetase and ligase. Structure 3m7a structure corresponds to the C-terminal (27-165) fragment of the YP_496102 (Saro_0823) protein and it is structurally unique, as the best hits from Dali have a Z-score of 3.8 (1nt0, 2j1t, 3kq4) and it is thus a likely candidate for a new fold. Interestingly, many of the top Dali hits are involved in sugar metabolism. There are no obvious active site-like cavities on the protein surface of 3m7a (http://www.topsan.org/Proteins/JCSG/).	0.00015486
NC_008312.1|WP_081432419.1|2613496_2613754_-|hypothetical-protein	gnl|CDD|366375	pfam00931, NB-ARC, NB-ARC domain.	4.36582e-06
NC_008312.1|WP_011611368.1|2634406_2637040_-|formylglycine-generating-enzyme-family-protein	gnl|CDD|224182	COG1262, COG1262, Uncharacterized conserved protein [Function unknown].	1.66268e-82
NC_008312.1|WP_081432534.1|2626613_2626817_-|hypothetical-protein	gnl|CDD|368559	pfam05685, Uma2, Putative restriction endonuclease. This family consists of hypothetical proteins that are greatly expanded in cyanobacteria. The proteins are found sporadically in other bacteria. A small number of member proteins also contain pfam02861 domains that are involved in protein interactions. Solutions of several structures for members of this family show that it is likely to be acting as an endonuclease.	2.81064e-08
NC_008312.1|WP_155994669.1|2611092_2613351_-|tetratricopeptide-repeat-protein	gnl|CDD|274350	TIGR02917, TPR_domain_protein, putative PEP-CTERM system TPR-repeat lipoprotein. This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.	6.13133e-24
NC_008312.1|WP_011611363.1|2623271_2624444_+|DNA-replication/repair-protein-RecF	gnl|CDD|234608	PRK00064, recF, recombination protein F; Reviewed.	3.14419e-140
NC_008312.1|WP_011611370.1|2638092_2640024_-|trypsin-like-peptidase-domain-containing-protein	gnl|CDD|379142	pfam13365, Trypsin_2, Trypsin-like peptidase domain. This family includes trypsin-like peptidase domains.	1.57295e-11
NC_008312.1|WP_011611362.1|2621231_2622833_+|B12-binding-domain-containing-radical-SAM-protein	gnl|CDD|379101	pfam13282, DUF4070, Domain of unknown function (DUF4070). This is a bacterial domain often found at the C-terminus of Radical_SAM methylases.	1.36612e-66
NC_008312.1|WP_044136583.1|2631604_2632483_-|formylglycine-generating-enzyme-family-protein	gnl|CDD|224182	COG1262, COG1262, Uncharacterized conserved protein [Function unknown].	1.33361e-77
NC_008312.1|WP_011611361.1|2618664_2620149_-|protein-kinase	gnl|CDD|319862	cd16383, GUN4, porphyrin-binding protein domain GUN4. GUN4 is a porphyrin-binding protein involved in chlorophyll biosynthesis regulation and intracellular signaling, found in aerobic photosynthetic organisms. It has been implicated in retrograde signalling between the chloroplast and nucleus. GUN4 can bind protoporphyrin IX (PIX) and magnesium protoporphyrin IX (MgPIX), substrate and product of the Mg-chelatase, as well as heme and cobalt protoporphyrin IX (CoPIX). It may play a role in protecting plants from reactive oxygen species (ROS)-mediated damage.	6.58617e-71
NC_008312.1|WP_011611369.1|2637043_2638096_-|AAA-family-ATPase	gnl|CDD|223786	COG0714, COG0714, MoxR-like ATPases [General function prediction only].	3.17184e-14
NC_008312.1|WP_011611360.1|2617043_2618561_-|protein-kinase	gnl|CDD|319862	cd16383, GUN4, porphyrin-binding protein domain GUN4. GUN4 is a porphyrin-binding protein involved in chlorophyll biosynthesis regulation and intracellular signaling, found in aerobic photosynthetic organisms. It has been implicated in retrograde signalling between the chloroplast and nucleus. GUN4 can bind protoporphyrin IX (PIX) and magnesium protoporphyrin IX (MgPIX), substrate and product of the Mg-chelatase, as well as heme and cobalt protoporphyrin IX (CoPIX). It may play a role in protecting plants from reactive oxygen species (ROS)-mediated damage.	1.36037e-72
NC_008312.1|WP_011611367.1|2633968_2634310_-|diversity-generating-retroelement-protein-Avd	gnl|CDD|380307	NF033474, DivGenRetAVD, diversity-generating retroelement protein Avd. Avd (accessory variability determinant) is part of diversity-generating retroelement (GDR) system through which a portion of a protein-coding gene can be rewritten, creating diversity that can affect host range. The founding member of this family, bAvd, from a Bordetella bacteriophage, belongs to a retrohoming element called BPP-1. Members of this family are four-helix bundle proteins, related to those of family TIGR02436, some of whose members are found in long intervening sequence (IVS) regions in 23S rRNA.	5.35796e-43
NC_008312.1|WP_052845770.1|2616547_2616751_-|DUF192-domain-containing-protein	gnl|CDD|376876	pfam02643, DUF192, Uncharacterized ACR, COG1430. Two structures have been solved for members of this large (>500 members) family of bacterial proteins present mostly in environmental bacteria and metagenomes (distant homologs are also present in several Plasmodium species). TOPSAN analysis for Structure 3pjy shows that there is much similarity with the other solved structure, Structure 3m7a, solved for UniProt:Q2GA55 (Saro_0823), a homolog of Thermotoga maritima TM1668, UniProt:Q9X1Z6., The homolog in Caulobacter crescentus (CC1388), UniProt:Q9A8G6, is associated with CspD, a cold shock protein (CC1387), UniProt:Q9A8G7. However, the genomic context of UniProt:Q2GA55 is most conserved with a putative xylose isomerase, suggesting a possible role in extracellular sugar processing. Saro_0821, UniProt:Q2GA57, is annotated as an AMP-dependent synthetase and ligase. Structure 3m7a structure corresponds to the C-terminal (27-165) fragment of the YP_496102 (Saro_0823) protein and it is structurally unique, as the best hits from Dali have a Z-score of 3.8 (1nt0, 2j1t, 3kq4) and it is thus a likely candidate for a new fold. Interestingly, many of the top Dali hits are involved in sugar metabolism. There are no obvious active site-like cavities on the protein surface of 3m7a (http://www.topsan.org/Proteins/JCSG/).	1.18192e-11
NC_008312.1|WP_011611373.1|2643844_2645032_-|glycosyltransferase-family-4-protein	gnl|CDD|340831	cd03801, GT4_PimA-like, phosphatidyl-myo-inositol mannosyltransferase. This family is most closely related to the GT4 family of glycosyltransferases and named after PimA in Propionibacterium freudenreichii, which is involved in the biosynthesis of phosphatidyl-myo-inositol mannosides (PIM) which are early precursors in the biosynthesis of lipomannans (LM) and lipoarabinomannans (LAM), and catalyzes the addition of a mannosyl residue from GDP-D-mannose (GDP-Man) to the position 2 of the carrier lipid phosphatidyl-myo-inositol (PI) to generate a phosphatidyl-myo-inositol bearing an alpha-1,2-linked mannose residue (PIM1). Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate residue. This group of glycosyltransferases is most closely related to the previously defined glycosyltransferase family 1 (GT1). The members of this family may transfer UDP, ADP, GDP, or CMP linked sugars. The diverse enzymatic activities among members of this family reflect a wide range of biological functions. The protein structure available for this family has the GTB topology, one of the two protein topologies observed for nucleotide-sugar-dependent glycosyltransferases. GTB proteins have distinct N- and C- terminal domains each containing a typical Rossmann fold. The two domains have high structural homology despite minimal sequence homology. The large cleft that separates the two domains includes the catalytic center and permits a high degree of flexibility. The members of this family are found mainly in certain bacteria and archaea.	2.40224e-61

Protein sequences

>NC_008312.1|WP_081432534.1|2626613_2626817_-|hypothetical-protein
MRSYLFWKFGKPPDLVIEIVSPTPGNELGSKLIDYRKLRASYYVVYNQLKNLVKMSCKYFGFVVFYK
>NC_008312.1|WP_011611364.1|2624875_2625889_+|hypothetical-protein
MGNISDLEANISQMQQLLNAAQNDIQKKTFEEIINRLSQELEKEKSKLNYSKVKTIEVDKPLEGKVKKKIIQLGKHESKKNQNLKLKCDSKIEEKSQLETEEILYNNEEESLPPKQDYLFHGLGVLYGRIVKRYEDNDNYYNAIIDDKTYQLIIINPRVRHFMKVDYNPEKNRYLTVYPNIVHYPQPRGGRKEPKVSFTIIAANDFPTLDLEPNEFRLFGLWQFIAVSRCPVISIHRNRKNDGSDRVSVIKERFKNNDKLHKNLTRANHVPLLWRDSPVKPFKFNPRFDKDKQGDRYFCKIKAKFLAYRGVWGFQELLVEPTLDIPKFYKPIKIAFS
>NC_008312.1|WP_011611363.1|2623271_2624444_+|DNA-replication/repair-protein-RecF
MYLKHLHLRQFRNYRDQQVKFDGAKTILLGDNAQGKSNLLESVELLSTLKSHRAIRDRDLILDSKQASKIQASLERQLGNIDLALTLRSQGKRTVAVNGETISRHLDFLSILNVVHFSSLDLDLVRGGPEVRRYWLDRLLVQLEPVYAHILLQYNQVLRQRNALLKKIRQQKMAAETTGSSPSILTQELALWDAQLATTGSRVIRRRQRLLQKLAPLAGEWHCAISGSMEVFKMEYLANVIVDSNELIIQDSLEGVRQAFLEKIKVRAIAEQYQGTTVVGPHRDDVIFTINDTPARQYGSQGQQRTLVLALKLAELQLIEEVVQEPPLLLLDDVLAELDLHRQNQLLEAISNRFQTLITTTHLGCFDGQWLQDTQILSVKSGNISSFLDF
>NC_008312.1|WP_011611362.1|2621231_2622833_+|B12-binding-domain-containing-radical-SAM-protein
MRVLLIYPLFPKSFWSFEKILELINRKVMLPPLGLVTVAAILPQEWEYKLVDRNVRSVTEAEWEWADLVILSAMIVQKEDLHDQIREAKRRHKLVACGGPYPTALPQEQLDSGVDFLILDEGEITLPMFVDAIKNGETKGIFRADGNKPDVTTTPLPRFDLLEMKYYESMSVQFSRGCPFQCEFCDIIVLYGRKPRTKTPAQLLAELDCLYDLGWRGSLFMVDDNFIGNKRNVKLLLKELKVWQAEHQYPFKITTEASVNLAEDPELMQLMVDSNLRAVFLGIETPDEDSLELTHKYQNNRNPLNEAVEKIIKSGIRVMAGFIIGFDGEKPGAGDRIVKFVEETTIPTAMFSMLQVLPNTALWHRLKKEGRLLDKGANINQVTLTNFIPTRPIEDIAREYVEAFWQLYDHEKFLDRTYRHFLIMGSPTAKSIAKMPSWMELRALLIICWRQGIKRKTRWKFWHHLWSIRKHNPSILPRYISTCAHIEHFYEYRNIVRENIEVQLAEYLAKNKQLNIIKEKVNTQNQKTTEEVA
>NC_008312.1|WP_011611361.1|2618664_2620149_-|protein-kinase
MSNFFNSKCLSPNPNHSEFCYNWGNKLFLVERYWIKSLIREGNFCRTFLAVDEFQKSQPLCVIKQFILPYQKNEFAQEAEKLKLLGRHPQIPKTYTYFTVDSRQYLVQEFIQGKTLKQELNNYGVFNEAQIRELLIDLLSLLQFVHSYDVIHQDIKPENIIRRETDKKLVLVDFGVSNIIPKVQRNTVTLTITGSAEYSASEKSIGKSHLASDLYSLGVVCLHLLTNIRPLNLYDVMEMEWVWRDSLNGNFVSDKLGKVLDGLVEPKLRKRYQNVQSVFDDLQPDISTVQKKSLLTKKSVSTNVNSSHIYTFPPQSQTSFSHTKKNQRLPQYSASNDVPLVSAREINYENLRELLATGKWKEADEETIKCMLKVTKREKELWLRVKDINNFPCEDLLSIDKLWLKYSDGQFGFSVQTQIYQSLGGTRKYDSKIWEAFADQVGWRRKGRWLGYSQLSFNLKICGYIGHLPAAVALNKWSRFGIGYLFYHTNICRL
>NC_008312.1|WP_011611360.1|2617043_2618561_-|protein-kinase
MSQCLNPECPSPNSDNSEFFQKCGNKLFLVERYWIKSIIGEGNFCRTFLAVDELKPSKPFCVIKQFLSQAQGSENVEKAAELFAEEGEKLKLLGKHPQIPELYTYFTVDSRQYLVQEFIQGKTLEQELDNYGVFNESQIREFLIDLLSLLEFVHSYDVIHQDIKPENIIRRETDKKLVLVDFRISKIIPKFQRFNVTGTVLNSAEYSPPEQSVGKLKLASDLYSLGLVCLYLLTQMTPFDIYDVIEMEWVWRDFLNKTFISDNLGKVLDGLVELKLRKRYQNVQSVLDDLKPIFSPSQQNLLLTKQSVSINVNSSYVSPFFPQSQMSSSHNKKNQQLPQYSASTDVPLVSVREIKYQKLRYLLATQQWKEADLETTNCMLTVAQREEEGWLRVEDIDNFPSEDLGTIDKLWVKYSNGKFGFSVQKQIYQSLGGTRQYDRKIWEAFSDQVGWRQEGKWLWYSDLDFSINTHYKGHIPSCSSWPEMAVGSLLSLVSWAVSLLSRKDL
>NC_008312.1|WP_155994364.1|2616707_2616857_-|hypothetical-protein
MMFRTELPDNQGMLFSIDPLRNVIFVLEKCVYSFGYGFFEEWGSSGNFF
>NC_008312.1|WP_052845770.1|2616547_2616751_-|DUF192-domain-containing-protein
MVFLKNGAVRAIFSNLPLCSFELCPTYGTYTPVDGVLELRAGRAIQLGFRVGDRINIQSVFLSQNTF
>NC_008312.1|WP_081432419.1|2613496_2613754_-|hypothetical-protein
MDFCWRHWQDGDVLLIFDDVVNYEDISDFLPPGGSRFKVLMTTRQKWLRQSFQRLELEVLDKDAALELLISFVGDGRIGGGARGG
>NC_008312.1|WP_155994669.1|2611092_2613351_-|tetratricopeptide-repeat-protein
MTGRRGVAAAFEFSWQELDEDDQELGCFLSLFACARIPWYLVEGCLPEVDEVELEDRRDDKLVNLSLLQSLGENCYEFHPLIREFFRNKNKLLEFDLVEEMKGNICGVIADAVRKIPYDEYITVEKVKEVKVDIPHITEVAENLAEYLSDDDLILPFISLGGFYHCQALYSLAQPWLDRGREIAERRLDKNNADIATVYNCLAALYFAQGKYEAAEPLYLQAFKIVKTVLPENHPNIAVSLNNLKNLYYSQGKYEAAEPLLLQAVEIYKIALPENHPNIAVSLSNLAELYRAQGKYEAAEPLLLQAIEIYKIALPENPPNIAVSLSNLAELYRAQGKYEAAEPLLLQAIEIYKIALLENHPNIAVSLSNLAELYRAQGKYEAAEPLLLQAIEIYKIALPENHPNIAVSLSNLAELYRAQGKYEAAEPLLLQAIEIYKIALPENHPNIAVSLSNLAELYRAQGKYEAAEPLLLQAIEIYKIALPENHPNIAVSLSNLAELYRAQGKYEAAEPLLLQAIEIYKIALPENHPNIAVSLSNLTNLYYSQGKYEAAEPLLLQAIEIYKIALPENHPNIAVSLSNLAELYRAQGKYEAAEPLLLQAIEIYKIALLENHPNIAVSLNNLTNLYYSQGKYEAAEPLLLQAIEIYKIALLENHPNIAVSLNNLTNLYYSQGKYEAAEPLLLQAIEIYKIALPENHPNIAVSLSNLAELYRAQGKYEAAEPLLLQAIEIYKIALLENHPNIAVSLNNLTNLY
>NC_008312.1|WP_044136583.1|2631604_2632483_-|formylglycine-generating-enzyme-family-protein
MVRITIRKKKEQAEYYTEDLGNNVELAMVKIPAGKFIMGAPENELDSTHSERPQHEVTVPEFFMGRYPITQGQWKAVVETTEKIERDLKPDPSYFKDDYEKYNRWTRPVEKVSWLDAQEFCARLSQKTERNYQLPSEAQWEYACRAGTTTPFHFGETITTDLANYRGKDDGEKKSSGSYGRGPKGEYREQTTPVGYFKVANLFGLYDMHGNVWEWCEDDSHDNYEGAPNDGSPWVSSNQNTTKYTTKRLRGGSWYDFPWWCRSAFRGYYFSVEAVNDFVGFRLVSFPPRTPE
>NC_008312.1|WP_155994365.1|2632599_2632785_+|hypothetical-protein
MARPTYSHMPVLAQKSAGGETHKTKTNIVVVRLVRVIVVAVRRATPPRIVVPGAAVCLPHI
>NC_008312.1|WP_011611367.1|2633968_2634310_-|diversity-generating-retroelement-protein-Avd
MNELPIIQKTYDFIKWYVPVLNRLPRNYRLGLGTRIINHLYDLLENLIRARFSTSEKLEILQNLNIKLDVIRHQTRLLSDFELISSDRYKYINIQINGIGSDLGSWTKNLSEP
>NC_008312.1|WP_011611368.1|2634406_2637040_-|formylglycine-generating-enzyme-family-protein
MSSSSFEHTIKLLIDRLARTGILEGLELSDENIADSIWLALQMGTVKTPQKPKPKYEQQPEQLPIIFEDSDPQPVTEREPQVSVITEESIDQTPEKPPVKGLPFQTPAAPALQNVLELGRALRPLMRKVPSLSRKTLDEEETVNVIAEQDIWLPVTKPEPERWLDLELVVEESSSAFIWRETVNEMQEVLETQGAFKNVRVWSLLSSNTKKLKLVRRHNSGKPKQRQHSHRELIHSNQRGVVIFVSDCTSKIWQNGTVHHWLKVWSEKNPTTILQLFPEYLWDSTQLGVGSKFFGTAVAPGVPNPRLVLENLPPWIPINWKNALVLPVILPEPELLKSWCRIVSGASNSRVPIFLFDLSFVEKQFCQKQEDSPPELPTPKKEISPTTRVRKFLATTSITAQRLAGMMAAAPVNLSVVNLIRKTLLKEATTVHVAEVYMGGLLAPTDSKDDQPTYEFLPGVRKELNQAMGRNETTAVLDAVSRYIAEKIDRPIRSFRALLTLLPQYEEEDREQVLPFAQVAVDVLENLGGEYAEFAEKVAQKIRPVSVPPIFETPESEVRSEPQIQTDTFDVAFIEVQETVTFEFDLARLEKRRSELLRLFGYRWAIKKQRRQVTGIVEDLGNGIKLEMVEIPPGKFLMGSPEDELERESREGPQHQVNISAFLMGRYPVTQGQWKAIVDNVPKIERDLKSNPSYFKGNDRPVERVSWYDAVEFCARLSKYTGRNYGLPSEAQWEYACRAGTTTPFHFGETITTDLANYDGNYTYGQGTKGKYREETTPVGSFEVANPFGLYDMHGNVYEWCEDDMHDNYEGAPNDGSPWLSGNQNTTKYSTKVLRGGSWLNYPWWCRSAYRYDFSSDGAVIINFGFRLVSFPPRTLE
>NC_008312.1|WP_011611369.1|2637043_2638096_-|AAA-family-ATPase
MNNWEIFKENTEPHDGIQNLPPPPSWRPFGQENRPGESRLKRRGETFQARSDEVKMVNAALYLRRPLLVTGKPGTGKSSLAYAVARQLKLGEVLYWPVTTRTILKEGLYSYDAIGRLQEVKQQERLNNQTFSSEQYREQIQQIEKYITLGPLGTALLPSKYPRVLLIDEIDKSDIDLPNNLLAILEEGLFEIPELVRIKKEVNKVTVRTAYSDETEAETGSQMEAEIENGRITCTAFPLVVMTSNGERDFPAPFLRRCLPLRMKSPTQEELTKIVIAHFNQNTAEQEKIQTLIKNFIDLQDEKTLATDQLLNAIFMVTKGRIPATEGKSFFDDELVQQLLQDLGRAEAED
>NC_008312.1|WP_011611370.1|2638092_2640024_-|trypsin-like-peptidase-domain-containing-protein
MVLELSIVRIFKSGGGVAGSGFLVSNEYILTCAHVVAYCLDTPKKTAHIIMRQKEIPDEIIEVNFPIFEKGKIGEKLETKVTFWRPLNDQENIQDIAVLKLINSDLLPEDAKPINLIQIGNQSLKENEFEALGFPKKGSDGEWATGKLMGPIGRGLIQLEGTKQTGLRLESGFSGTAIWDKNLQGVVGMAVKADQERPEAKVAFMIPTDLILQVGDLATVCRVDGRIQGAIAILENYFEDYTTEIRYAYNLSLPEISIPLSSGKSLDEYPGSLNEMIQNLDDRTKENYSLLERFICFLLLHLEDLKKPSELCQKLTEWLEKYSQNIEDLKAVLRKEKALKNQENFQIKQPEPYLLVAAIEKSKGFILKAWLIENPQNYTPENPQGFHSFIDEENVLMNAKGTIVSNKNTSEFNQAKNLTELLQFFWADVSERYDFNLEKIAIFLPYKLIDRDIKPVDQYISDPNIPEYFQTLLGEQCEITLRFSERLRLSGNSNAELNKFNQKWRSLTSRQSARVIDIFHPSATSGNRKKFFRQIFADDVAAVRLTEVLQPEKRESVMEAFYYAGIPVALWMRPEAENIDCAEELQNICNACNSLSNLPKAIKAKRSEAWEQDIDRHIGNHLSLLWEDPDIVPPVNELRMLES
>NC_008312.1|WP_044137279.1|2640086_2640437_-|hypothetical-protein
MTKLVKFQLDDDDESFVYVEVDEKLPVSSNEDEDEELIGIGDEVAQQAKQTLGKALSSIKPVANAIIKKVQDLNQPADAVEVKFGIKMSGELGAVIASGSAEVNYEITLKWNKTEG
>NC_008312.1|WP_011611372.1|2640870_2641221_-|hypothetical-protein
MFEFLASVIITQGILDWEPVGYNTKATTLINMNTIEGLGNNLWRAEVLKQYDQEADDGMKQVYMVVEIDCNIGRFASQLIRRQTGLGEIIAETTLEGNRFISPQGSEAGILMICDR
>NC_008312.1|WP_155994366.1|2641514_2641664_-|hypothetical-protein
MCNIDLLSVANISWNQNIPGAQVNLQVYTVAAPQPSVLGEIKGLWQGVQ
>NC_008312.1|WP_011611373.1|2643844_2645032_-|glycosyltransferase-family-4-protein
MKILLVCTEKLPVPCIRGGAIQTYIDGILPFLKRDHEVTVFSVADPELPDQEIRDNILYKRSSRKTSEEYYHAVTNFVAGREFDWIVIYNRPKYLPMVAEVAPNSRFILSMHNEMFHAKKIEPEEAILCLERVEKVVTVSKFIADGIAKLFPGYEHKLTPVYAGVDLKLFQPRWIEGLEGKRKEKLAALGLEDKQVILYVGRLTDKKGPHLLISAMTKVIKKHPSAVLLLVGSKWYGNNEENDYVREIKVKAEQLGGAVQMTGFIPPYEVADYFLLGDVFVCASQWEEPLARVHYEAMATGLCTITTGRGGNPEVIIPGKNGIVITDYENSGAFADCIDYLLSMPNKREEMGKRGRELAELYYSWSRVAWDILSIINDSTSMYSSSSLERFGQTG

Crispr_ID: NC_008312_22

• CRISPR_ID: NC_008312_22
• CRISPR_location: 2921383-2921463
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NC_008312_22

Consensus_repeat	Method
TTTTACTAAGGTATCAGATAATAT	CRISPRCasFinder

spacers of NC_008312_22

>22.1|2921407|33|NC_008312|CRISPRCasFinder
AAATAATGGTGATTTGTCTCCTAATACTATAGA

CRISPR arrays and Neighbor proteins around NC_008312_22

CRISPR arrays

The CRISPR arrays of NC_008312_22

>merge|NC_008312|22|2921383-2921463|CRISPRCasFinder
TTTTACTAAGGTATCAGATAATATAAATAATGGTGATTTGTCTCCTAATACTATAGATTTTACTAAGGCATCAGATAATAT

>NC_008312|22|18|2921383-2921463|CRISPRCasFinder
TTTTACTAAGGTATCAGATAATAT	AAATAATGGTGATTTGTCTCCTAATACTATAGA
TTTTACTAAGGCATCAGATAATAT

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_008312.1|WP_011611516.1|2884845_2886438_+|helix-turn-helix-domain-containing-protein	unknown	unknown	gnl|CDD|238045
NC_008312.1|WP_081432422.1|2918932_2919043_+|universal-stress-protein	unknown	unknown	gnl|CDD|223662
NC_008312.1|WP_011611521.1|2902685_2905277_-|T9SS-type-A-sorting-domain-containing-protein	unknown	unknown	gnl|CDD|367843
NC_008312.1|WP_011611522.1|2905930_2913829_-|T9SS-type-A-sorting-domain-containing-protein	unknown	unknown	gnl|CDD|367843
NC_008312.1|WP_011611530.1|2932408_2932807_+|response-regulator	unknown	unknown	gnl|CDD|381100
NC_008312.1|WP_011611531.1|2933587_2935822_-|amino-acid-permease	unknown	unknown	gnl|CDD|273347
NC_008312.1|WP_011611532.1|2936255_2937893_+|DUF697-domain-containing-protein	unknown	unknown	gnl|CDD|368297
NC_008312.1|WP_011611518.1|2888236_2896291_+|intein-containing-DNA-polymerase-III-subunit-alpha	unknown	unknown	gnl|CDD|181933
NC_008312.1|WP_011611519.1|2897003_2898995_-|tandem-95-repeat-protein	unknown	unknown	gnl|CDD|197563
NC_008312.1|WP_011611535.1|2954959_2955835_+|M48-family-metallopeptidase	unknown	unknown	gnl|CDD|320684
NC_008312.1|WP_011611517.1|2886803_2887118_+|hypothetical-protein	unknown	unknown	unknown
NC_008312.1|WP_011611526.1|2921965_2923147_+|hypothetical-protein	unknown	unknown	unknown
NC_008312.1|WP_081432538.1|2947741_2950771_+|hypothetical-protein	unknown	unknown	gnl|CDD|273296
NC_008312.1|WP_011611524.1|2918579_2918786_+|hypothetical-protein	unknown	unknown	gnl|CDD|366180
NC_008312.1|WP_011611529.1|2928041_2930663_-|DNA-topoisomerase-4-subunit-A	unknown	unknown	gnl|CDD|235502
NC_008312.1|WP_011611515.1|2883902_2884400_+|IS630-family-transposase	unknown	unknown	gnl|CDD|379267
NC_008312.1|WP_011611533.1|2939720_2941274_-|trans-splicing-intein-formed-DNA-polymerase-III-subunit-alpha-C-terminal-partner-DnaE-C	unknown	unknown	gnl|CDD|236003
NC_008312.1|WP_011611528.1|2926395_2927916_+|hypothetical-protein	unknown	unknown	unknown
NC_008312.1|WP_155994376.1|2923767_2926284_+|hypothetical-protein	unknown	unknown	unknown
NC_008312.1|WP_011611523.1|2916259_2918377_-|glycogen-debranching-protein-GlgX	unknown	unknown	gnl|CDD|224440

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_008312.1|WP_011611516.1|2884845_2886438_+|helix-turn-helix-domain-containing-protein	gnl|CDD|238045	cd00093, HTH_XRE, Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators.	9.16566e-07
NC_008312.1|WP_081432422.1|2918932_2919043_+|universal-stress-protein	gnl|CDD|223662	COG0589, UspA, Universal stress protein UspA and related nucleotide-binding proteins [Signal transduction mechanisms].	1.27995e-05
NC_008312.1|WP_011611521.1|2902685_2905277_-|T9SS-type-A-sorting-domain-containing-protein	gnl|CDD|367843	pfam04151, PPC, Bacterial pre-peptidase C-terminal domain. This domain is normally found at the C-terminus of secreted bacterial peptidases. They are not present in the active peptidase. It is possible that they fulfill a similar role to the PKD (pfam00801) domain, which also are found in this context. Visual analysis suggests that PKD and PPC are distantly related (personal obs:Bateman A, Yeats C).	1.98888e-07
NC_008312.1|WP_011611522.1|2905930_2913829_-|T9SS-type-A-sorting-domain-containing-protein	gnl|CDD|367843	pfam04151, PPC, Bacterial pre-peptidase C-terminal domain. This domain is normally found at the C-terminus of secreted bacterial peptidases. They are not present in the active peptidase. It is possible that they fulfill a similar role to the PKD (pfam00801) domain, which also are found in this context. Visual analysis suggests that PKD and PPC are distantly related (personal obs:Bateman A, Yeats C).	2.2029e-08
NC_008312.1|WP_011611530.1|2932408_2932807_+|response-regulator	gnl|CDD|381100	cd17548, REC_DivK-like, phosphoacceptor receiver (REC) domain of DivK and similar proteins. Caulobacter crescentus DivK is an essential response regulator that is involved in the complex phosphorelay pathways controlling both cell division and motility. It localizes cell cycle regulators to specific poles of the cell during division. DivK contains a stand-alone REC domain. REC domains function as phosphorylation-mediated switches within response regulators, but some also transfer phosphoryl groups in multistep phosphorelays.	1.10862e-34
NC_008312.1|WP_011611531.1|2933587_2935822_-|amino-acid-permease	gnl|CDD|273347	TIGR00930, Solute_carrier_family_12_member_1, K-Cl cotransporter. [Transport and binding proteins, Other].	3.9856e-142
NC_008312.1|WP_011611532.1|2936255_2937893_+|DUF697-domain-containing-protein	gnl|CDD|368297	pfam05128, DUF697, Domain of unknown function (DUF697). Family of bacterial hypothetical proteins that is sometimes associated with GTPase domains.	3.92088e-59
NC_008312.1|WP_011611518.1|2888236_2896291_+|intein-containing-DNA-polymerase-III-subunit-alpha	gnl|CDD|181933	PRK09532, PRK09532, DNA polymerase III subunit alpha; Reviewed.	0
NC_008312.1|WP_011611519.1|2897003_2898995_-|tandem-95-repeat-protein	gnl|CDD|197563	smart00187, INB, Integrin beta subunits (N-terminal portion of extracellular region). Portion of beta integrins that lies N-terminal to their EGF-like repeats. Integrins are cell adhesion molecules that mediate cell-extracellular matrix and cell-cell interactions. They contain both alpha and beta subunits. Beta integrins are proposed to have a von Willebrand factor type-A "insert" or "I" -like domain (although this remains to be confirmed).	1.25964e-49
NC_008312.1|WP_011611535.1|2954959_2955835_+|M48-family-metallopeptidase	gnl|CDD|320684	cd07325, M48_Ste24p_like, M48 Ste24 endopeptidase-like, integral membrane metallopeptidase. This family contains peptidase M48 family Ste24p-like proteins that are as yet uncharacterized, but probably function as intracellular, membrane-associated zinc metalloproteases; they all contain the HEXXH Zn-binding motif, which is critical for Ste24p activity. They likely remove the C-terminal three residues of farnesylated proteins proteolytically and are possibly associated with the endoplasmic reticulum and golgi. Some members also contain ankyrin domains which occur in very diverse families of proteins and mediate protein-protein interactions.	3.15676e-75
NC_008312.1|WP_081432538.1|2947741_2950771_+|hypothetical-protein	gnl|CDD|273296	TIGR00845, Sodium/calcium_exchanger_1, sodium/calcium exchanger 1. The Ca2+:Cation Antiporter (CaCA) Family (TC 2.A.19)Proteins of the CaCA family are found ubiquitously, having been identified in animals, plants, yeast, archaea and widely divergent bacteria.All of the characterized animal proteins catalyze Ca2+:Na+ exchange although some also transport K+. The NCX1 plasma membrane protein exchanges 3 Na+ for 1 Ca2+. The E. coli ChaA protein catalyzes Ca2+:H+ antiport but may also catalyze Na+:H+ antiport. All remaining well-characterized members of the family catalyze Ca2+:H+ exchange.This model is specific for the eukaryotic sodium ion/calcium ion exchangers of the Caca family [Transport and binding proteins, Other].	1.78146e-22
NC_008312.1|WP_011611524.1|2918579_2918786_+|hypothetical-protein	gnl|CDD|366180	pfam00582, Usp, Universal stress protein family. The universal stress protein UspA is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. UspA enhances the rate of cell survival during prolonged exposure to such conditions, and may provide a general "stress endurance" activity. The crystal structure of Haemophilus influenzae UspA reveals an alpha/beta fold similar to that of the Methanococcus jannaschii MJ0577 protein, which binds ATP, though UspA lacks ATP-binding activity.	3.58156e-05
NC_008312.1|WP_011611515.1|2883902_2884400_+|IS630-family-transposase	gnl|CDD|379267	pfam13565, HTH_32, Homeodomain-like domain.	1.37222e-08
NC_008312.1|WP_011611533.1|2939720_2941274_-|trans-splicing-intein-formed-DNA-polymerase-III-subunit-alpha-C-terminal-partner-DnaE-C	gnl|CDD|236003	PRK07373, PRK07373, DNA polymerase III subunit alpha; Reviewed.	0
NC_008312.1|WP_011611529.1|2928041_2930663_-|DNA-topoisomerase-4-subunit-A	gnl|CDD|235502	PRK05560, PRK05560, DNA gyrase subunit A; Validated.	0
NC_008312.1|WP_011611523.1|2916259_2918377_-|glycogen-debranching-protein-GlgX	gnl|CDD|224440	COG1523, PulA, Type II secretory pathway, pullulanase PulA and related glycosidases [Carbohydrate transport and metabolism].	0

Protein sequences

>NC_008312.1|WP_081432422.1|2918932_2919043_+|universal-stress-protein
MVIGYRGHSILSATVLGGVSSYMIHRAHCSVHILRG
>NC_008312.1|WP_011611524.1|2918579_2918786_+|hypothetical-protein
MYKNILVAIDTSVIGDRMFNIALQLAKLGHSSLLLVHILSEVAQESPLRFWPMNIGYDPQIMKADHHH
>NC_008312.1|WP_011611523.1|2916259_2918377_-|glycogen-debranching-protein-GlgX
MNLNILPGNTFPIGATVCQDPKGVNFSIYSKNATAIELLLFDEPLAAKPKQVILLDPTQHRTHHYWHIFISGIGAGQIYAYRVYGPFNPEKGHRFDGTKVLLDPYARIVVGQEKYSRKAATGNGNNCAYALKGVVVDPTTYDWEDDKPLETPYAKTVIYEMHVGGFTRHPNSGVAPEKRGTFAGLIEKIPYLKELGITAVELLPVQQFDEQDVREPLINYWGYSQIAFFAPHHSYSSRKDIFGPMDEFRDMVKALHKEGIEVILDVVFNHTAEGNENGPTVSFRGLENSTYYILEKNDRGYYSNYTGCGNTFNTNNPFVHRLIVDCLCYWVREMHVDGFRFDLASVMSRSMTGDPLEDPPVLWAIESDPVLAGTKIIAEAWDAAGLYQVGSFIGDRFAEWNGHYRDDVRQFVKSDPQIVEKLAARIMGSPDIYPKPDREPNHSINFITCHDGFTMNDLVSYNEKHNEANCEDNRDGANHNFSWNCGIEGTTDQEEIEMLRLRQIKNFFTILFFSQGTPMILMGDEVRRTQLGNNNSYCQNNKSSWFDWSQIDQQNDLLRFVKKIIHFTQELQITQLDKVLATVGAIPESSLVSTKEKTNLNKVPNISWHGIHLGIPDWNVGSRTLAFSLKHPESGEYFHIMLNAYWKPLMFELPPLERGENWYLIVNTAFTSPKDFNNLDVATKVIGVRYRLEPRAAVILMTKRD
>NC_008312.1|WP_011611522.1|2905930_2913829_-|T9SS-type-A-sorting-domain-containing-protein
MREEVIGLEPSQNILGFELESKHQSVNMMFPVYSVQEPDVLEQVPMDEVDNQLPQIIVPSKIINSSQLDLTTVASTPEDIDGKDPLTGLTTEEANIPPEKNAYTIKQRKARKKDPGNNVKTALNLGRVGDDVITYNDNIGMKSGKARDKNDYYKFNLKGKENDVSIVVDGLKDNANLELRNKNGKSVLFNSTQKGKKPETIEQELAQGTYFLRVYPKGNAKTKYELSISAEEILQDPDSKSPGATNLGPLGKKKKVITDEIGFKEKGTRDNRDFYKFTLTEKLNNLNIVLDGLKDDANIQLLDEDGKTIIDQSRSKGKKKEIIDQILEGGTYYLKVTPTGNARTKYRLSLDGDKIDDPDGTRTRAENLGTLGNKPIKKRDEIGFEVGGKRDQKDYYQFNLNRDSEVNFSLDGLNQNVDLKLLGSKGNLLYSSTNKGKEVEKISTILDKGKYYALVEPMGSDRSEYTLSIDGDSKIQDPDAKLPGKNLGKLKGKTISRIDDIGLKKKGFLDTSDFWRIELTKETDLTITLDRLSQNADLELYDKDGTTLIYSSKEKGKKPEEISSILDKGIYYIKVKSKGGSSSKYKLSVTGNTQIGEKDDALPGTNLGELGNQKIVKKDEIGFESSQNIRDVGDFYNFSLAEQRGVNITLDGLTGDANLFLVGNDGGEIEVSNNKGKRNEIINEILQPGNYYIGVKPNGGKVKTNYNLEVTTNLQKDDFNNRQNAQQLGTLNLQDQVTQNNRVGFKEGSLIDQADFYSFKLTETSDVNLSLDGLDGDANLLLLDNKNTLDESTAKGLKAENIKKKLEAGTYYAAIFPVSGAKTDYELTLGVTQKTVDLSSLKFEALDVQDGLKAGERLKVNYQVNNIGNTKADAFEVGFYLSKDEGIDKGDFLLGTAKVKSLSGDKNTKKLAKQLTLPESGDNFWQGSGDYYLGMMVDVQDAIVENNELNNTGSQRVGVDLSSDLIVSGFDVQEKTVNPGQKFNAKVTLNNAGGKLDDFRVGFYVSEDNEITTSDELLGSKMVTSLGGKKSTTINKQLTLPVASVSGVKKYFIGAIADDQDVLREVNETNNVSKEKVSLSPVPQDNAGNKLNKGRKVGVLGNKTQKFSDWVGDFYGVSEDTHDYYKIELDDRSRLNLNLKGLSANANLYLYDSDGDLLQKSEESENKEEAIDIKLLPGTYYGLVWKDDGGNTNYDLEMSALPLEYPVPQITGWNRNTALNIGAVSATPIAKTEYVGNPHGFVDDLNDFYKFQVEGSGSQVQIDLTGLNKNADLYLYNSESSSSIARSETLQKADESIVKNLSPGTYFIEVQSINNAKTNYNLQVVGTPLPDNGAGENPDQALDLGTLGETIVNDWVGDIDGTDYYMFAVSENSTVDMSLTGMSGNANLKLFDNKEKSLSSSSQEGNADDGIAINLTPSNYFVEVERYSGVVGTPYNFQISATSRAEDLVGNDLETAKDIGALTTFNQTEWVGSFDVSDYYKFSLAEDSEVDLNLTGMNSNGQLYLYDSEGEVLTSSRNDSNTDEAIITNLNPGTYYVGVWRYKLYSREATSVNYNLTASATTIPDSGGNTRETAGDIGDISTPKTLSNWVGNVDPNDYYKFTLTQDSDVSLNLTGMDDNGQLYLYDSEGEVLTSSINDSNTDEAIITNLNPGTYYVRVWRYKSYSREATSVNYNLTASATTIPDSGGDTLETAGDMGDISTPKTLSNWVGSADPNDYYKFTLTEDSNVNLNLTGMDDNGQLYLYDSEGEVLTSSINDSNTDEAIITNLNPGIYYVRILRYKSYSREATSVNYNLTASATTLPNSAGDDFETARDLGMVSAAQTIRDWVGDLQYDDYYKFSVAANSSINLKLAGLTANTGLYLYDSKEKLIGSSDNDSNADESIVYNLASGNTYYVKVEGRSPYYGGDNTYYNLELSATPLTYSPDNIVGNTEAQTKNIGALGATQSFTDFVGNQYVDRDKNDFYQFVLGETSTVNLNLGSMTADADLVLLDSEYSQITESSQLTNVDEVIIRNLQAGTYIAGVKSIENGNTGYNLQLSATAHPDGAGDTVGTARLIGTLAGPQTFNDWIGNVDEKDYYQFVIDAVSTVNINLGGMTGNGNIGLYDIEESPLLYSQNTENADDVIVADLNPGTYYVQVWNDRGNFGTNYSLQLSPTVRVDNAGGADSPLDLGALTTINATNWVSPGIDEEDYYKFSVGENSAVSLNLTGLTDAINFNLYNSAMEEIASAPNDENTETAIAKNLTPGNYLVEISNFWGNGTEYNFVATATPISDNAGNDFDVARNIGAVSATQAFSDWVGRIDRNDYYKFDIPQNSEVTINLTGLASDADLYLYDSQENEIVSSTNDDTNNELITEKLPSGTYYALVWQSSGHTNYNLDFSATPLTYSAPNIVGNTEAQTKNIGALGEAQTFTDFVGISQNIDSDKEDFYQFTLAEDSTVSLSLNGLSANADLTLRNNEYYWLDDSTNFLNASENITRNLVAGTYIVEVESIGDASTGYNLQLSAVAHPDAAGNTFDTSKPVENLAEVQTFNDWVSNIDENDYYKFNLSEKRTVNIELSGLSDEASLYLYNSSGDTFSYDANGHYQGSSYVWKINSGEMGSISRLLNSGNYFVGVFYESYNGLGTNYSLSMSAT
>NC_008312.1|WP_011611521.1|2902685_2905277_-|T9SS-type-A-sorting-domain-containing-protein
MANDTRADALDLGVIELEPTVTNDQIGFRVDGKRERNDFYKFKLDEESDFNLTLDKLDKNANVQILDSDGSVLFKSTKPGKQREVIDAELDAGEYFVRVLPKGMAQTDYRLSLNADPITDDELPGVSLGVLDSEEEVTFTDEIGFAKGGQRDKNDYFNFTLDQDSDVSLTLDQLKKNANVQIWDDKGKTLLLQSRNKGRQEETINAILEKGDYLVRVFPQGRARTSYRLGLSADEILPPEKLPGTDVGDLLASEEPHFAIEDIGFGRGRQRNTKDYYTFELSQEASFYAELDQLQRNADIYLYEYDPDEPEELGSRLNKSTRKGRRPDTISEFLPEGHYALEVRPRGAAKTDYRLELDARINVDDFPAPEMAKDLGELVPTPTNETGNNVGLLTDDRFRDQADWFKFTLSAEKNVDLTLDELRVNAADAEIYDADGTTRLYKSKNKGKQRETINENLDAGTYYVKVVARGSSNTNYRLSLSADEPISPTDTFPLGTLESPTEYSNNDKIGGEGGGVRNSQDEYTFTINELTEFNATLDQIKRNVDLELYKGSMLVDSSKEKRNNPEIIDQVLEPGDYTLRVMPMGNAETTYRLGIDTEVVAEGDETFEVGSLLDLNNNEYKKKGRIGDFQNGSRNLNDFYNLTLDNNSNFMLTLDEMTRDANVMVLDSEGDMVLSGFNPENAPEILSDTLDAGDYTVQVFPVGNAKTSYFLKMNADPLPDPPDDMDDGDDDDMGDDGDETEVDPITGDPDGTPEDATDLGSDLLTQSGKIGFMEDGVDDVNDYYKFTLDANDDIRIILSGLTQNADLTLLGSDGETEIFTEIFKSSNPGTNTERINATLEAGDYYLQVEAVGDAQSDYTINFF
>NC_008312.1|WP_011611519.1|2897003_2898995_-|tandem-95-repeat-protein
MAKKTKSSITNIVDRKGGLNPDVVDVTLVPGDNVTFDITAKVTKKSSTKLPLDLVFLSDLSGSYGDDLPVLQDLVPKLVSSVRDIQPNSQFGLASYIDKPKDPFGGPKDFVYRMESAITKSRTDFQKAMDDLKIGNGNDGPEAQLEALMQLALREKEIGFRKKSRRVVVLSTDANYHKAGDGKKAGIKTPNNGDTVLDGKPAGTGEDYPSIDQVRDALQEAGIVPIFAVTGNQVRNYKKLVDKLGFGTVERLSRDSSNLVKVVTEGLEEVFSDLTIVPQSDEFGYIKSIKPTTYENVRPGQSRTFEVKLGITDLDASQKDRLSLEVLGYGETKVNVTPIVNTKPIASNDNLATNAGSKLVIKPKELLANDTDKDGDKLSISKVGKASNGKVILGKNGKVTFTPDKDFTGKASFEYTIDDGNKGRDSATVTVQVRDNSDPIAKDDKVFFVRPKLFHAIQAKKLLKNDQDKDGDKLTIIKVSNATKGEVELTKSGEITFTPSGKHKKFSKGSFEYTISDGKGGTDTAKVMLKRVGDLPSSKRSAGSEKRDSLTGNIDDKAPGIPLGTVVDPLTQSSDIGFKNGGKVDQNDYYNFVVPEPSFVSIKLDGLRSNANLELYDSDKVSLDSSTNSGNAPEEINTFLFPDTYVVGVFDQGSGTPYNLSIL
>NC_008312.1|WP_011611518.1|2888236_2896291_+|intein-containing-DNA-polymerase-III-subunit-alpha
MSFVGLHIHSDYSLLDGASQLPQLIDRAVELGMPAIALTDHGVMYGAIQLIKLCRNKNIKPIIGNEMYVIKGDIEKQQRGKKFHQVVLAKNTQGYKNLVKLTTLSHLHGFQGKGIFARPCINKELLEKYHEGLIVTSGCLAGEVPQNIMRGELEEAKKIAKWYKDLFGEDYYLEIQDHGFQEDRVVNTGIVTIAKKLKIKIVATNDSHFISCRDVEAHDALLCINTQKLIAEEKRMRYSGTEYLKSAEEMKQLFRDHLENEVIEEAIANTLEVANKVKAYEGILGEPRIPDYPIPPDHNADTYLEKLAWSGLLERLKLKQKSEISPIYKERMETELKVLQDKGFSTYFLVVWDYIKYARDNNIPVGPGRGSAAGSLVAYSLRITNIDPVHHGLLFERFLNPERKSMPDIDTDFCIENRDVMIKYVTQRYGEERVAQIITFNRMTSKAVLKDVGRVLGISFGEANKMAKLIPVARGKPAKLKVMISDETPSPEFKKAYDNQETPIEDNKAGKISTISVRQWIDMAIRIEGTNKTFGVHAAGVVISKEPLDEIVPLQRNNDGSVITQYHMEDIESLGLLKMDFLGLKNLTIIQNTAELIKKNHHLPLVPDDLPANERKAIEILAKGNTKKMPEDVKKTYDLIKSGDLEGVFQLESSGMVDVVKKLKPTSIEDISSILALYRPGPLDAGLIPKFIDRKHGSEKIEYQHPKLEPILKETYGVLCLPKGTLIDQPDGSREAIENIKSGEVILTSDGRKVWEAKVAKQWRSGVREILKITLSSGTVIYSGKNHRFLTPEGDKFAWELQPQVGRVKNALIYGSAVYEKWQVSSNQKQLRKNDAYLLGLLVGKSNLISSTPNVSFSTQGAITWGKNLIDETWGGEAKHYFDTSRRQVYLNFNTQSKPTALTEFLDGIYGAQNWQVESVAKHLPEDILDYSEKDRIDLLRGLWDSGGFDGKKLLYYPGSSPQLLSQVCQLLGSLKIDYYLADNSVRISDRSRFIDILENYQMSSQQKEEISESYLPASSWFLKGGSENNIQKTDSSSRKTGEASQQKATLFTQNLFSAQTPAENWEKVGENHLLSSWFLTDASENNIQKTDSSSRKTGEASQQKATLFTQNLFSAQTPAENWEKVRENHLLSSWFLTNASEIYLQRIDSSSRKTGEASQQKATLFTQNLFSVQTPAENWEKVRENHLLSSWFLTDASENNIQKTDSSSRKTGEASQQKATLFTQNLFSAQTPAENWEKVRENHLLSSWFLTNASENNIQKTDSSSRKTGEASQQKATLFTQNLFSAQTPAENWKKSRKNHLPSSWFLKGGSENNIQKTDSSSRKTGEASQQKATLFTQNLFSAQTPAENWEKVRENHLLSSWFLKDASENNIQKTDSSSRKTGEASQQKATLFTQNLFSAQTPAENWEKVRENHLLSSWFLTDASENNIQKTDSSSRKTGEASQQKATLFTQNLFSAQTPAENWEKVRENHLLSSWFLTDASENNIQKTDSSSRKTGEASQQKATLFTQNLFSAQTPAENWEKVRENHLLSSWFLTNASENNIQKTDSSSRKTGEASQQKATLFTQNLFSAQTPAENWKKARENHLLSSWFLTNASEIYLQRTDSSSRKTGEASQQKATLFTQNLFSVQTPAENWKKARENHLLSSWFLTNASEIYLQRTDSSSRKTGGASQQKATLFNQNLFSVQTPAENWEKVRENYLLSSWFLTNASEIYLQRTDSSSRKTGEASQQKATLFTQNLFSVQTPAENWKKARENHLLSSWFLTNASEIYLQRTDSSSRKTGGASQQKATLFNQNLFSVQTPAENWKKARENHLLSSWFLTNASEIYLQRTDSSSRKTVEASQQKATLFTQNLFSAQTPAENWEKVRENYLLSSWFLTNASEIYLQRIDSSSRKTGEACQQKATLFNQNLFSAQTPAENWKKVRENHLLSSWFLTDASENNIQKTDSSSRKTVEASQQKATLFTQNLFSAQTPAENWKKSRKNHLPSSWFLTDASENNIQKTDSSSRKTGEASQQKATLFTQNLFSVQTPELENWECEKTYLQDVRVVHVVSVEEVGEAECFDLEMEDQSSPYFLAEGVVVHNCYQEQIMKMAQDLAGYSLGEADLLRRCLSGSTKVIDAATGNLFSLKEIAAQPEYWLSRKVFSLDLKSQQVVQQPITEIHPNGVRDVWQITTRTNRKVCATDDHLFYTVLGWKPLKDFSVGDRLGLPNKIPINYRSQISDSKVKFTAYLIGEGYLYTNSFSCSYFCNSDGELIADFYGCAEELFGSSAPIEKQLHLGNKSVIYVRIGLISGLKNWVDSYLQCANSRVQEIPNWIFSLSQSQLQLFLGILWSTSGIFDETIGYTYYSSNSEVLVRQVQHLFLRLGIVSLFNVNKVKGQGELDVSYVVEVRGREDMLKFYKLIKPYLSSYKQGLCESCYLVIKYQQSYQFKYFLTPDFFDLIVKAKKASSMTRALGVCGGEISSVWNFQNTSNRSLSFDKFNNFSTVLADEELTAIANSDVFWDEIISIEYIGKEEVFDLTIPETHNFIANDFIVHNCMGKKKVSEMEKHREKFIDGAAQRGVSSVVAKDLFEQMIKFAEYCLTYETEIMTVEYGPLPIGKIVEYRIECTVYTVDKNGYIYTQPIAQWHNRGMQEVYEYSLEDGTVIRATPEHKFMTEDGQMLPIDEIFERNLDLKCLGTLEL
>NC_008312.1|WP_011611517.1|2886803_2887118_+|hypothetical-protein
MDKPSTSTGLITGLVATLFFSISFSLLEYTIKSSIILGFIGGISAGLLGFWSQIESRPETPEKADAKSVDSIKLSKSTSVIKPRLQTPKERSGVSVLSWLFKQK
>NC_008312.1|WP_011611516.1|2884845_2886438_+|helix-turn-helix-domain-containing-protein
MTHKMTENCLGCATCLPKIQCPTGAIFVENEQYSINPELCNGCEGYYEEPQCVVHCSISSPVPLQPKKGRYKVETRTPTSSDLFPDNKHSPFASSIVMWEACNILAQRQSLLWTIDEKGKFIYQRSIKQGQGSISLSLQHLEHSCQTDNATVLQEMDIRAACIHLIYAAHATIIDKPWEQEFVISDQQIERYLGLEKRKDLSKATKLSLIKNLAQQPCRITTTIDWPQQGRINAFSLPESKLWHMIDIQHHFSEDSTGCKHLVGLTFKVRAGIWAKYFLNKEACKDRTAFYQYGILPKSVLTTVMSIWQQHEGTARMLLWLLFKTKMGREQRLTVPTLMRVAYGEQKVRRASSFRDDRKRLMKTFESDLEVLSHYGIKPEFDPVTYPQEIQPMWAKLASLPDDGDAALDFWIDDGSNHRRLTDYGPRGKWNMLMNARILWFQLPQEWDRHLAEFEKHKLRYTIKRKRTKKLSVICGEQIMMARKNQQLSQRQLATMLGKSQSWIRDIESGRFQLKGEDQMLLQNLLGLGG
>NC_008312.1|WP_011611515.1|2883902_2884400_+|IS630-family-transposase
MPAKDFLSSIQKKRLQKALRESGCCHFRERVLMLLLLNDGKTYSEISEFIGCSYRTVAYWCVHGDPDKLDSLRDQREHGNFRKATEEYIQLLIEVTKKSPNQLGYECSNWSGERLANYLAQQTGIKLSGTQVRRILKQKNISLPKSRVQLYERKNNRKNVSRPSK
>NC_008312.1|WP_011611526.1|2921965_2923147_+|hypothetical-protein
MVQEQQRQKNTRIKLGIWGTSSAGKTVYMLMLYHYLQRSKRKDRFLVKAGNEQTDKFLKKHLISRIYKGEFPSTTTKEDKYNSYSYKLKRNNSDTIVELTFLDLSGEIWKSRGYKVKTNNKKNEDVSVAKYLTQCHGILILLSPLKEDYPPKNSYFSLLEGLFRLMLREIPESEFKLEQYVVFGITKADHDEIYQRTIDRNFYQLIMEIIGPQASLEGLESYFHLEIVEEKDGTKRVNVNGENNRCCFLPISPFAKYYDEDGGKMISPVIENKTEEEPRANESQQEPPKAAGKRQEKQREDPFKKNLGKKQKNNDDYETPSTADNSEGGQREGHSSDNDDYDTPSTTNDDEPNQKQGKYKIDTRVEWRPQNVVEPIEWLIQRIENHPPKIFDE
>NC_008312.1|WP_155994376.1|2923767_2926284_+|hypothetical-protein
MRGKKLLIAIADNKDEISKFLSKLDNLLLLFIPMVWRSKLSIAMGKDIDLEVCKWANIVVSFQEEKPSYWTDDWVCLDLASTIITPNLSIESEYVKDFIEPLKDDFGSLTILCKKFAENENVGLKLKTTNNQKNSSGFRPDSSNVSLLLQGKPLDFSHPSVDFIANYPKDDTYKTQLFSKYFLPMKSELKIFLENVGKDQKTVLIILWEAIKQNLTTDADIAVLCLSKMFALLTKDEFLKRLQELKAADVMELISHGLWKETQKNVNKEDSLEFINKELQLISLKFIKEERKRYKYEEFKKFVSIHLQEIFFSDVEKFQLWDSFLAQEIDREKFLDLFNEQLIPLMPKIDLEIFENSYLIKYLKSSFPIVFLGLQDVLSNRNFSKLCLVSSDLKINNATTNKLYLNFLESQSPTYESSQDLLIDTINRSIDLKTTVLKIQDLSDVYQWFYKKKPGLFDNLSKLYSTNPSWSDWEELASFLYPDDHNQENRVYFLDKIVAQKFTAEVLKTWFNLLKSEPNNPKIKESFLNGKTWKNLRDETIKNMYCYLTTEVPDYVSKLIQWASEKSRFDLINGKLTESAIEIWENNKTIDQQTWQILMFSPVQANLSNEKRFRMRIADLLCEPNSLSLTNNVEIKSQNISKERQNKSESQQKKPRDLFKKYTAHKTIQENVSSTDDPLTNSTSTQMSNNNQNEGKVNESRRDLPLYNKEQKTLHLLTELARKKINKFKDDPEKIEGFLELCETFEIKILEVLVEVDLKNCPGVFFKYLHSKNYDRNSTEYIRCFEKMLSQIQSNTKERDKIIDFVRDIGKNMIGEGDKELRELAVDSLASWARQGLK
>NC_008312.1|WP_011611528.1|2926395_2927916_+|hypothetical-protein
MINDNSQNQETNFWICNGEEKNLPHPPQMLHYGDECPICHNVKKIKRNPPPPNPDTINITRPTDFEVPPEVDTNSIKGTRPTASQVSPTGQKSKRDWPLVGALTILNLGSAFTTVRGASQILPSFVAYPMGITIQGVLFALIARLFLKHAPLIKWVVVGCFSTFSVYTSFFAYYDLLNRETREKTRIELANSGHQSLVGEFFTPIQNKVNSLESEIGIINKKIEKETQGERGGRPKGCGKVCQQLKEEREILEEQKAQLKPLVNRLQPLFNYNVEGKSPKEIFDTDFKALSKVGENCLPKELLSQLEITCLPDQYLKALNPQNSENYERLRLTYIDPDLEVDFLAPILKVMKGEGSAIASVIMALLIDGCIILLGIGVEIRPQVTRQRQQTLTLQIKDGKIVEFLNLLLSKSENETIEIEKSDNNKDEYQNLLTWLSVNTRWIWQDEDKSWYFRSSSSKENFQKWLINQINLQNQARASTNLLESWKKKPPEYFVLEMPIVSKDQD
>NC_008312.1|WP_011611529.1|2928041_2930663_-|DNA-topoisomerase-4-subunit-A
MAKKLNLLSGKVITTSLHTEMQQSYLEYAMSVIVGRALPDVRDGQKPVHRRIIYAMHELGLTPDRPFRKCARVVGDVLGKYHPHGDQAVYDAMVRMIQNFSSRYPLLDGHGNFGSIDNDPAAAMRYTESRLASIGNEGLLTQISEAIVDFTNNFDGSQQEPKVLPAQLPFLLLNGSSGIAVGMATNVPPHNLGEVVDGLIALIDNPNISDQKLFELIPGPDFPTGGEIVSTDGIIDTYTKGRGSIPMRGVATIEQVPTGRGRRTKTAIVVTELPFQVNKAGWIEKTADLVNAGKIEGIADLRDESDRSGIRVVIELKREADPSVVLHHLYRNTDLLSKFGAIMLALVNGQPQQLSLRTLLQEFLNFREETLTRHYTHELQIAQARSHIVAGLLTALKELDRVIDILRNAPDGNTAKVSFQESLGLSENQADAILAMPMRRLTGLEKQKLEEEHEQLMGKIQELENLLGDRHQLLKALKKELRTLKRKYNDPRRTRIIDQIKLKNADDFASISQQKKYLEAGNKEIDIKTKGRVIKSKNITVKSPILTLEAAPPPTEKVVIEFSHRGYVRRIPAKGFEKYKIDKKSHITMENSEDFTTNIIEATTDKTLVLLTRTGKAYPLKVNNIPSASNRSTIRNENKGVPLVTLLPPSATKEITDARKEIIIGQFILNEAKENKDLIMLTQNGKIKRLCLSDLSDMRNRGVTVIKLKEDDELRYVSLGKTGEQVVLATSGGRLLRLQIDDEKLPLMGRAAQGSQATRLRKQEELVGCVTLDIGSNLLLVSQHSYGKQIPVTALRVANRGGIGQNVFQFTRQDDILAGIVASSSNVLVQVLTTDGRVFGMIADRVKVDQQDDHGHRLLKLGAKEKIIKVVGY
>NC_008312.1|WP_011611530.1|2932408_2932807_+|response-regulator
MSTILIVEDDQVNAKVFSKILTKRGGLNVKHTEDVEEVVKIARSKEADLILMDVSLTRSVYNGKAFDGIQITQLLKSDPQTCKLPIILLTAHAMSGDRENFLNKSGADGYISKPVVDHQEFVNHIKSFLSED
>NC_008312.1|WP_011611531.1|2933587_2935822_-|amino-acid-permease
MKLFKSSNLPEETQATPKTSPERINEKGLGTFGGVYTPSILTILGVIMYLRFGWVVGNVGLLGTLLIVTLSTVITLLTSLSVSAIATDRIVRGGGAYYMISRSLGLETGGAVGIPLYFAQALSVALYTIGFAESIVDTFGSFNKLYVALITTIAVAVLAFTSAEIAIKAQYFIMGAIALSLISFAFGHPLEITSIDILATPEQSTEPFWTVFAVFFPAVTGIMAGVSMSGDLQEPNRSIPIGTLAAVGTGYVIYMILPIILAMRADPTTLIEKPLIMKEMAVWEPAILFGVWGATLSSAIGSILGAPRVLQALARDGVLPRWLSFLGNGSKLKDEPRIGTAVTLGVATATVCIGDLNIIAPVLTMFFLTTYMVLNVSAGIEGFLQSPSFRPTFKVHWSLSMLGALGCLAVMFLINAIATVIAAVIVLTIFIWLQRRELETTWGDARRGIWMALVREGILLLGEEDTKNWRPHILVLSGVPKKRWLLIRFADHLTHNRGIITVCSVLPSSSRDVSQQSDTEETIREYVEKRGVQVLVRVVTATDFFDGAKLLVETYGIGPLTPNTVVLGDSQEASRRDRYCQLVAHIHKAKKNVVIFRENSDHGFGQYRRIDVWWGGLQNNGGLMLLLAYLLRTDMDWRNAQINLKLVVPEQTAAQKTQANVDNLIQSLRISASSQVLVSNGRSFYDILHESSRNADLIFLGIRTPGENFTEYYQDLQSKTLGLPTTVFVLAAPGFSYGEVLSDR
>NC_008312.1|WP_011611532.1|2936255_2937893_+|DUF697-domain-containing-protein
MPTSRLLTLILGFSLILLLIIWLVGSLSWLYSQILWSAPPLVANLLLLLLIMLMGIVLFTLVYYLRLYTIGKNKRQRSSKITIPVVKSEAVSESLKAVRQQIIQIQDEVARQALLNRSQKIEYIAAQGNIKVVVFGTGSAGKTSVVNALMGRMVGRAEAPIGSTKVEETYCLKLSALEREILITDTPGILEAGVAGRERGQLAKVLATEANLLLFVVDNDLQQSEYMALKSLAAIGKRSLVVFNKTDLYTTEDHEAILVRLRERLVGVISKMDIVAIAACPNSVRLETGEVYQPEPDIIALIERLAAVLRLEGEDLIADNILLQSQLLGEEARSLIDSQRRKRGERVVEKFQWIGAGVIAATPVPVIDVLATAAVNAQMVIEIGKVYGCELNLKRGQELAMSLAKTLASLGIVEGVIKLISMALQLNVATFILGKAIQGVTAAYLTRIAGQSFIEYFSQNQDWGDGGITEAVKKQFQLTKKDEFVKLFIQDAITKFVEPLTNIYSSDEKVETESEAEINYYSQSDKKVYDYDDWKTESRNKKEDW
>NC_008312.1|WP_011611533.1|2939720_2941274_-|trans-splicing-intein-formed-DNA-polymerase-III-subunit-alpha-C-terminal-partner-DnaE-C
MVKIVSRKLAKTENVYDIGVTKDHNFVLANGLIASNCFNKSHSTAYAYVAYQTAYLKANYSLEYMAALLTANSGDQDKVQKYLANCQKFNIEVEPPNINQSEVDFTPLPKVATKEIKDKILVGLSAVKNVGEGAIEAILKARKEGGEFKSLADLCDRVNLNALNSRTLESLIKCGAFDKIEANRHQLIKDLEGVMKWAQDRNKDRNIGQLSLFDNHIPGAKNSAFDSVPKSSPVSDFPAKEKLEYEKEILGFYVSDHPLKYAQEQNQIQDAISIAQMKEKKSNSKIKLVVMLAGIKPHVTKKGDPMAFIQVEDMTGQLDAVVFPKVYQEIKELLTENSLLVLKGKVDNKDDESQLLVESAETIEKVMADAVKQEEKPVTELDNYQNESRDEEIKKYQDIGKAEKPVEQLETQRNLRKTELSKTENSSAKQRQIIILELSVDKIPEDNSLFEQIQAILKEQSSGDEEKAKVAVGTLIFDDQRQQLVQFGREFWVEDGQTTINRFIGIGIEAKIIPFPY
>NC_008312.1|WP_081432538.1|2947741_2950771_+|hypothetical-protein
MTSISDSSLSDFSNSNFTIKPEDFITVSSPDGGNTLEPGKTYTINWRDNIDENVKLELYKAGSFFGNISSSTASNGSYSWAVPTSLTSGSDYQVKITSISDSSLSDLSNSNFTIKPEDFITVSSPDGGNTLKRGKNYRITWRDNIDENVKVELYKAGFLFGTISSSTESDGSYSWAVPTSLSTGNDYQVKVTSISDGSLSDFSNSNFTIKPEDLAKISIGDTKITEGNTNKAAKFKVTLDNPTTETVKVNYTTANQTAKVNQDYKLTKGTLTFRPGETNKTITVPILGDKRDEAEEKFNLNLSRPRNAKLKDAQAIGTIVDNDQPPQISIGDAKVTEGNKGKKNMEFEVKLNDPSGKTVKVSYGTVEGSAKSGKDYQKTSGVLTFKPGQRKKILNVPILGDTRDEKNENFQVKLSGAKNAKLSDKNAVGVIRDNDETVPQISIGDAKVTEGNKGKKNMEFEVELNKGSSKTVKVSYGTVDGSAKSGKDYQKTSGVLTFKPGQRKKILNVPILGDTREEKNENFQVKLSGAKNAKLSDKNAVGVIRDNDETVPQISIGDAKVTEGNKGKKNMEFEVELNKGSSKTVKVSYGTVEGSAKSGKDYQKTSGVLTFKPGQRKKILNVPILGDTRDEKNEQFQVKLSGAKNAKLSDKNAVGVIRDNDETVPQISIGDAKVTEGNKGKKNMEFEVELNKGSSKTVKVSYGTVDGSAKSGKDYQKTSGVLTFKPGQRKKILNVPILGDTRDEKNENFQVKLSGAKNAKLSDKNAVGVIRDNDEIIGKTPQISIKDTKITEGKKGEKDMKFEVKLDKSSSQIVRVNYETVDGSAKAGKDYEKKKGVLKFQPGETKKTVNISILGDTVDEKNENFRIKLSGAKNANLSDKNAIGMIRNNQVPESFKDAVDLGILSSEQTVVVDDIGFATGPVNRNTEDYFCFKVEKEGLVSIFVDGFIQDLGIKLYGDDESLLNQSNEKGNTTKEKINTILDPGVYYLKVFPLGVAATEYKLRVNIVDS
>NC_008312.1|WP_011611535.1|2954959_2955835_+|M48-family-metallopeptidase
MALTKTQLIGLKANHFRHPLDLEATNALKQLPGIDLLVRQLLSPLGEQFFYMENIASSVLVSEAQLPNLHKTLLDACQALDIEPPQLYIRQNPVPNAYTFAMRGKQPFIVVHTSLIELLNLEEIQAVLGHELGHLKCEHGVYLTLGNLIVLAAGQISTWGGIIAQSLQSKILEWLRCAEFSCDRAALLATQNSQVVVSALMKLAGGSPTISPQLNVDAFLAQARAYNELSNTEVGEVLKEVQTAQLTHPLPVLRAKEIDMWASSKKYQDILQNLAKDVYNNQRIKGGWRNW

Crispr_ID: NC_008312_23

• CRISPR_ID: NC_008312_23
• CRISPR_location: 2941350-2941874
• CRISPR_type: TypeV
• Repeat_type: NA
• Spacer_info: 8 spacers
• Cas_protein_info: cas14j

Consensus repeat of NC_008312_23

Consensus_repeat	Method
AGGTGTNAATTTTTTGAGGT	CRT

spacers of NC_008312_23

>23.1|2941370|38|NC_008312|CRT
TTTAGGTTTTAGGTTTTAGGTTTTAGGTTTTAAGTTTT
>23.2|2941428|60|NC_008312|CRT
TTTAGGTTTTAGTTTTTAGGTTTTAAGTTTTAGGTTTTAAGTTTTAGGTTTTTAAGTTTT
>23.3|2941508|33|NC_008312|CRT
GTTAATTTTCTGAGGTTTTAGGTGGTAGGTTTT
>23.4|2941561|38|NC_008312|CRT
TTTAGGTGGCAGGTTTTAGGTTTTAGGTTTTAAGTTTG
>23.5|2941619|49|NC_008312|CRT
GTTAATTTTTTGAGGCGTCAATTTTTTGAGGTTTTAGGTGGTAGGTTTT
>23.6|2941688|38|NC_008312|CRT
TTTAGGTTGCAGGTTTTAGGTTTTAGGTTTTAAGTTTG
>23.7|2941746|49|NC_008312|CRT
GTTAATTTTTTGAGGCGTCAATTTTTTGAGGTTTTAGGTGACAGGTTTT
>23.8|2941815|40|NC_008312|CRT
TTTAGGTTGCAGGTTTTAGGTGTTAGGTGTCAATTTTTTG

CRISPR arrays and Neighbor proteins around NC_008312_23

CRISPR arrays

The CRISPR arrays of NC_008312_23

>merge|NC_008312|23|2941350-2941874|CRT
AGGTGTCAATTTTTTGAGGTTTTAGGTTTTAGGTTTTAGGTTTTAGGTTTTAAGTTTTAGGTGTCAATTTTTTGAGGTTTTAGGTTTTAGTTTTTAGGTTTTAAGTTTTAGGTTTTAAGTTTTAGGTTTTTAAGTTTTAGGTGTCAATTTTTTTTTGTGTTAATTTTCTGAGGTTTTAGGTGGTAGGTTTTAGACGTCAATTTTTTGAGGTTTTAGGTGGCAGGTTTTAGGTTTTAGGTTTTAAGTTTGAGGTGTCAATTTTTTGAGGTGTTAATTTTTTGAGGCGTCAATTTTTTGAGGTTTTAGGTGGTAGGTTTTAGACGTCAATTTTTTGAGGTTTTAGGTTGCAGGTTTTAGGTTTTAGGTTTTAAGTTTGAGGTGTTAATTTTTTGAGGTGTTAATTTTTTGAGGCGTCAATTTTTTGAGGTTTTAGGTGACAGGTTTTAGGTGTTAATTTTTTGAGGTTTTAGGTTGCAGGTTTTAGGTGTTAGGTGTCAATTTTTTGAGGTGTTAATTTTTTGAGGT

>NC_008312|23|6|2941350-2941874|CRT
AGGTGTCAATTTTTTGAGGT	TTTAGGTTTTAGGTTTTAGGTTTTAGGTTTTAAGTTTT
AGGTGTCAATTTTTTGAGGT	TTTAGGTTTTAGTTTTTAGGTTTTAAGTTTTAGGTTTTAAGTTTTAGGTTTTTAAGTTTT
AGGTGTCAATTTTTTTTTGT	GTTAATTTTCTGAGGTTTTAGGTGGTAGGTTTT
AGACGTCAATTTTTTGAGGT	TTTAGGTGGCAGGTTTTAGGTTTTAGGTTTTAAGTTTG
AGGTGTCAATTTTTTGAGGT	GTTAATTTTTTGAGGCGTCAATTTTTTGAGGTTTTAGGTGGTAGGTTTT
AGACGTCAATTTTTTGAGGT	TTTAGGTTGCAGGTTTTAGGTTTTAGGTTTTAAGTTTG
AGGTGTTAATTTTTTGAGGT	GTTAATTTTTTGAGGCGTCAATTTTTTGAGGTTTTAGGTGACAGGTTTT
AGGTGTTAATTTTTTGAGGT	TTTAGGTTGCAGGTTTTAGGTGTTAGGTGTCAATTTTTTG
AGGTGTTAATTTTTTGAGGT

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_008312.1|WP_011611538.1|2958688_2958859_-|hypothetical-protein	unknown	unknown	gnl|CDD|177653
NC_008312.1|WP_081432422.1|2918932_2919043_+|universal-stress-protein	unknown	unknown	gnl|CDD|223662
NC_008312.1|WP_011611525.1|2919565_2921767_+|hypothetical-protein	unknown	unknown	unknown
NC_008312.1|WP_011611530.1|2932408_2932807_+|response-regulator	unknown	unknown	gnl|CDD|381100
NC_008312.1|WP_011611532.1|2936255_2937893_+|DUF697-domain-containing-protein	unknown	unknown	gnl|CDD|368297
NC_008312.1|WP_011611537.1|2957063_2957879_-|helix-turn-helix-domain-containing-protein	cas14j	-	gnl|CDD|378838
NC_008312.1|WP_011611531.1|2933587_2935822_-|amino-acid-permease	unknown	unknown	gnl|CDD|273347
NC_008312.1|WP_044137313.1|2956693_2956984_-|hypothetical-protein	unknown	unknown	unknown
NC_008312.1|WP_011611535.1|2954959_2955835_+|M48-family-metallopeptidase	unknown	unknown	gnl|CDD|320684
NC_008312.1|WP_081432538.1|2947741_2950771_+|hypothetical-protein	unknown	unknown	gnl|CDD|273296
NC_008312.1|WP_011611542.1|2963590_2964661_+|Gfo/Idh/MocA-family-oxidoreductase	unknown	unknown	gnl|CDD|223745
NC_008312.1|WP_011611526.1|2921965_2923147_+|hypothetical-protein	unknown	unknown	unknown
NC_008312.1|WP_011611540.1|2960959_2961700_+|helix-turn-helix-domain-containing-protein	unknown	unknown	gnl|CDD|379173
NC_008312.1|WP_011611543.1|2965670_2966024_-|hypothetical-protein	unknown	unknown	gnl|CDD|366507
NC_008312.1|WP_011611541.1|2961696_2962806_-|glutamate-5-kinase	unknown	unknown	gnl|CDD|235460
NC_008312.1|WP_011611529.1|2928041_2930663_-|DNA-topoisomerase-4-subunit-A	unknown	unknown	gnl|CDD|235502
NC_008312.1|WP_011611533.1|2939720_2941274_-|trans-splicing-intein-formed-DNA-polymerase-III-subunit-alpha-C-terminal-partner-DnaE-C	unknown	unknown	gnl|CDD|236003
NC_008312.1|WP_011611528.1|2926395_2927916_+|hypothetical-protein	unknown	unknown	unknown
NC_008312.1|WP_155994376.1|2923767_2926284_+|hypothetical-protein	unknown	unknown	unknown
NC_008312.1|WP_011611539.1|2959028_2959595_+|DUF3611-family-protein	unknown	unknown	gnl|CDD|372001

HMMScan for Signature genes

Protein	Cas_name	Cas_description	E-value	Identity	Coverage
NC_008312.1|WP_011611537.1|2957063_2957879_-|helix-turn-helix-domain-containing-protein	cas14j	-	5.8e-44	145.8	2.5

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_008312.1|WP_011611538.1|2958688_2958859_-|hypothetical-protein	gnl|CDD|177653	PLN00014, PLN00014, light-harvesting-like protein 3; Provisional.	3.50791e-06
NC_008312.1|WP_081432422.1|2918932_2919043_+|universal-stress-protein	gnl|CDD|223662	COG0589, UspA, Universal stress protein UspA and related nucleotide-binding proteins [Signal transduction mechanisms].	1.27995e-05
NC_008312.1|WP_011611539.1|2959028_2959595_+|DUF3611-family-protein	gnl|CDD|372001	pfam12263, DUF3611, Protein of unknown function (DUF3611). This family of proteins is found in bacteria and eukaryotes. Proteins in this family are typically between 180 and 205 amino acids in length. There are two completely conserved residues (W and G) that may be functionally important.	6.71115e-61
NC_008312.1|WP_011611530.1|2932408_2932807_+|response-regulator	gnl|CDD|381100	cd17548, REC_DivK-like, phosphoacceptor receiver (REC) domain of DivK and similar proteins. Caulobacter crescentus DivK is an essential response regulator that is involved in the complex phosphorelay pathways controlling both cell division and motility. It localizes cell cycle regulators to specific poles of the cell during division. DivK contains a stand-alone REC domain. REC domains function as phosphorylation-mediated switches within response regulators, but some also transfer phosphoryl groups in multistep phosphorelays.	1.10862e-34
NC_008312.1|WP_011611535.1|2954959_2955835_+|M48-family-metallopeptidase	gnl|CDD|320684	cd07325, M48_Ste24p_like, M48 Ste24 endopeptidase-like, integral membrane metallopeptidase. This family contains peptidase M48 family Ste24p-like proteins that are as yet uncharacterized, but probably function as intracellular, membrane-associated zinc metalloproteases; they all contain the HEXXH Zn-binding motif, which is critical for Ste24p activity. They likely remove the C-terminal three residues of farnesylated proteins proteolytically and are possibly associated with the endoplasmic reticulum and golgi. Some members also contain ankyrin domains which occur in very diverse families of proteins and mediate protein-protein interactions.	3.15676e-75
NC_008312.1|WP_011611537.1|2957063_2957879_-|helix-turn-helix-domain-containing-protein	gnl|CDD|378838	pfam12323, HTH_OrfB_IS605, Helix-turn-helix domain. This is the N terminal helix-turn-helix domain of Transposase_2 pfam01385.	8.02998e-18
NC_008312.1|WP_011611531.1|2933587_2935822_-|amino-acid-permease	gnl|CDD|273347	TIGR00930, Solute_carrier_family_12_member_1, K-Cl cotransporter. [Transport and binding proteins, Other].	3.9856e-142
NC_008312.1|WP_081432538.1|2947741_2950771_+|hypothetical-protein	gnl|CDD|273296	TIGR00845, Sodium/calcium_exchanger_1, sodium/calcium exchanger 1. The Ca2+:Cation Antiporter (CaCA) Family (TC 2.A.19)Proteins of the CaCA family are found ubiquitously, having been identified in animals, plants, yeast, archaea and widely divergent bacteria.All of the characterized animal proteins catalyze Ca2+:Na+ exchange although some also transport K+. The NCX1 plasma membrane protein exchanges 3 Na+ for 1 Ca2+. The E. coli ChaA protein catalyzes Ca2+:H+ antiport but may also catalyze Na+:H+ antiport. All remaining well-characterized members of the family catalyze Ca2+:H+ exchange.This model is specific for the eukaryotic sodium ion/calcium ion exchangers of the Caca family [Transport and binding proteins, Other].	1.78146e-22
NC_008312.1|WP_011611542.1|2963590_2964661_+|Gfo/Idh/MocA-family-oxidoreductase	gnl|CDD|223745	COG0673, MviM, Predicted dehydrogenases and related proteins [General function prediction only].	3.9106e-59
NC_008312.1|WP_011611543.1|2965670_2966024_-|hypothetical-protein	gnl|CDD|366507	pfam01187, MIF, Macrophage migration inhibitory factor (MIF).	1.02361e-20
NC_008312.1|WP_011611541.1|2961696_2962806_-|glutamate-5-kinase	gnl|CDD|235460	PRK05429, PRK05429, gamma-glutamyl kinase; Provisional.	0
NC_008312.1|WP_011611529.1|2928041_2930663_-|DNA-topoisomerase-4-subunit-A	gnl|CDD|235502	PRK05560, PRK05560, DNA gyrase subunit A; Validated.	0
NC_008312.1|WP_011611533.1|2939720_2941274_-|trans-splicing-intein-formed-DNA-polymerase-III-subunit-alpha-C-terminal-partner-DnaE-C	gnl|CDD|236003	PRK07373, PRK07373, DNA polymerase III subunit alpha; Reviewed.	0
NC_008312.1|WP_011611532.1|2936255_2937893_+|DUF697-domain-containing-protein	gnl|CDD|368297	pfam05128, DUF697, Domain of unknown function (DUF697). Family of bacterial hypothetical proteins that is sometimes associated with GTPase domains.	3.92088e-59
NC_008312.1|WP_011611540.1|2960959_2961700_+|helix-turn-helix-domain-containing-protein	gnl|CDD|379173	pfam13413, HTH_25, Helix-turn-helix domain. This domain is a helix-turn-helix domain that probably binds to DNA.	2.25325e-17

Protein sequences

>NC_008312.1|WP_011611533.1|2939720_2941274_-|trans-splicing-intein-formed-DNA-polymerase-III-subunit-alpha-C-terminal-partner-DnaE-C
MVKIVSRKLAKTENVYDIGVTKDHNFVLANGLIASNCFNKSHSTAYAYVAYQTAYLKANYSLEYMAALLTANSGDQDKVQKYLANCQKFNIEVEPPNINQSEVDFTPLPKVATKEIKDKILVGLSAVKNVGEGAIEAILKARKEGGEFKSLADLCDRVNLNALNSRTLESLIKCGAFDKIEANRHQLIKDLEGVMKWAQDRNKDRNIGQLSLFDNHIPGAKNSAFDSVPKSSPVSDFPAKEKLEYEKEILGFYVSDHPLKYAQEQNQIQDAISIAQMKEKKSNSKIKLVVMLAGIKPHVTKKGDPMAFIQVEDMTGQLDAVVFPKVYQEIKELLTENSLLVLKGKVDNKDDESQLLVESAETIEKVMADAVKQEEKPVTELDNYQNESRDEEIKKYQDIGKAEKPVEQLETQRNLRKTELSKTENSSAKQRQIIILELSVDKIPEDNSLFEQIQAILKEQSSGDEEKAKVAVGTLIFDDQRQQLVQFGREFWVEDGQTTINRFIGIGIEAKIIPFPY
>NC_008312.1|WP_011611532.1|2936255_2937893_+|DUF697-domain-containing-protein
MPTSRLLTLILGFSLILLLIIWLVGSLSWLYSQILWSAPPLVANLLLLLLIMLMGIVLFTLVYYLRLYTIGKNKRQRSSKITIPVVKSEAVSESLKAVRQQIIQIQDEVARQALLNRSQKIEYIAAQGNIKVVVFGTGSAGKTSVVNALMGRMVGRAEAPIGSTKVEETYCLKLSALEREILITDTPGILEAGVAGRERGQLAKVLATEANLLLFVVDNDLQQSEYMALKSLAAIGKRSLVVFNKTDLYTTEDHEAILVRLRERLVGVISKMDIVAIAACPNSVRLETGEVYQPEPDIIALIERLAAVLRLEGEDLIADNILLQSQLLGEEARSLIDSQRRKRGERVVEKFQWIGAGVIAATPVPVIDVLATAAVNAQMVIEIGKVYGCELNLKRGQELAMSLAKTLASLGIVEGVIKLISMALQLNVATFILGKAIQGVTAAYLTRIAGQSFIEYFSQNQDWGDGGITEAVKKQFQLTKKDEFVKLFIQDAITKFVEPLTNIYSSDEKVETESEAEINYYSQSDKKVYDYDDWKTESRNKKEDW
>NC_008312.1|WP_011611531.1|2933587_2935822_-|amino-acid-permease
MKLFKSSNLPEETQATPKTSPERINEKGLGTFGGVYTPSILTILGVIMYLRFGWVVGNVGLLGTLLIVTLSTVITLLTSLSVSAIATDRIVRGGGAYYMISRSLGLETGGAVGIPLYFAQALSVALYTIGFAESIVDTFGSFNKLYVALITTIAVAVLAFTSAEIAIKAQYFIMGAIALSLISFAFGHPLEITSIDILATPEQSTEPFWTVFAVFFPAVTGIMAGVSMSGDLQEPNRSIPIGTLAAVGTGYVIYMILPIILAMRADPTTLIEKPLIMKEMAVWEPAILFGVWGATLSSAIGSILGAPRVLQALARDGVLPRWLSFLGNGSKLKDEPRIGTAVTLGVATATVCIGDLNIIAPVLTMFFLTTYMVLNVSAGIEGFLQSPSFRPTFKVHWSLSMLGALGCLAVMFLINAIATVIAAVIVLTIFIWLQRRELETTWGDARRGIWMALVREGILLLGEEDTKNWRPHILVLSGVPKKRWLLIRFADHLTHNRGIITVCSVLPSSSRDVSQQSDTEETIREYVEKRGVQVLVRVVTATDFFDGAKLLVETYGIGPLTPNTVVLGDSQEASRRDRYCQLVAHIHKAKKNVVIFRENSDHGFGQYRRIDVWWGGLQNNGGLMLLLAYLLRTDMDWRNAQINLKLVVPEQTAAQKTQANVDNLIQSLRISASSQVLVSNGRSFYDILHESSRNADLIFLGIRTPGENFTEYYQDLQSKTLGLPTTVFVLAAPGFSYGEVLSDR
>NC_008312.1|WP_011611530.1|2932408_2932807_+|response-regulator
MSTILIVEDDQVNAKVFSKILTKRGGLNVKHTEDVEEVVKIARSKEADLILMDVSLTRSVYNGKAFDGIQITQLLKSDPQTCKLPIILLTAHAMSGDRENFLNKSGADGYISKPVVDHQEFVNHIKSFLSED
>NC_008312.1|WP_011611529.1|2928041_2930663_-|DNA-topoisomerase-4-subunit-A
MAKKLNLLSGKVITTSLHTEMQQSYLEYAMSVIVGRALPDVRDGQKPVHRRIIYAMHELGLTPDRPFRKCARVVGDVLGKYHPHGDQAVYDAMVRMIQNFSSRYPLLDGHGNFGSIDNDPAAAMRYTESRLASIGNEGLLTQISEAIVDFTNNFDGSQQEPKVLPAQLPFLLLNGSSGIAVGMATNVPPHNLGEVVDGLIALIDNPNISDQKLFELIPGPDFPTGGEIVSTDGIIDTYTKGRGSIPMRGVATIEQVPTGRGRRTKTAIVVTELPFQVNKAGWIEKTADLVNAGKIEGIADLRDESDRSGIRVVIELKREADPSVVLHHLYRNTDLLSKFGAIMLALVNGQPQQLSLRTLLQEFLNFREETLTRHYTHELQIAQARSHIVAGLLTALKELDRVIDILRNAPDGNTAKVSFQESLGLSENQADAILAMPMRRLTGLEKQKLEEEHEQLMGKIQELENLLGDRHQLLKALKKELRTLKRKYNDPRRTRIIDQIKLKNADDFASISQQKKYLEAGNKEIDIKTKGRVIKSKNITVKSPILTLEAAPPPTEKVVIEFSHRGYVRRIPAKGFEKYKIDKKSHITMENSEDFTTNIIEATTDKTLVLLTRTGKAYPLKVNNIPSASNRSTIRNENKGVPLVTLLPPSATKEITDARKEIIIGQFILNEAKENKDLIMLTQNGKIKRLCLSDLSDMRNRGVTVIKLKEDDELRYVSLGKTGEQVVLATSGGRLLRLQIDDEKLPLMGRAAQGSQATRLRKQEELVGCVTLDIGSNLLLVSQHSYGKQIPVTALRVANRGGIGQNVFQFTRQDDILAGIVASSSNVLVQVLTTDGRVFGMIADRVKVDQQDDHGHRLLKLGAKEKIIKVVGY
>NC_008312.1|WP_011611528.1|2926395_2927916_+|hypothetical-protein
MINDNSQNQETNFWICNGEEKNLPHPPQMLHYGDECPICHNVKKIKRNPPPPNPDTINITRPTDFEVPPEVDTNSIKGTRPTASQVSPTGQKSKRDWPLVGALTILNLGSAFTTVRGASQILPSFVAYPMGITIQGVLFALIARLFLKHAPLIKWVVVGCFSTFSVYTSFFAYYDLLNRETREKTRIELANSGHQSLVGEFFTPIQNKVNSLESEIGIINKKIEKETQGERGGRPKGCGKVCQQLKEEREILEEQKAQLKPLVNRLQPLFNYNVEGKSPKEIFDTDFKALSKVGENCLPKELLSQLEITCLPDQYLKALNPQNSENYERLRLTYIDPDLEVDFLAPILKVMKGEGSAIASVIMALLIDGCIILLGIGVEIRPQVTRQRQQTLTLQIKDGKIVEFLNLLLSKSENETIEIEKSDNNKDEYQNLLTWLSVNTRWIWQDEDKSWYFRSSSSKENFQKWLINQINLQNQARASTNLLESWKKKPPEYFVLEMPIVSKDQD
>NC_008312.1|WP_155994376.1|2923767_2926284_+|hypothetical-protein
MRGKKLLIAIADNKDEISKFLSKLDNLLLLFIPMVWRSKLSIAMGKDIDLEVCKWANIVVSFQEEKPSYWTDDWVCLDLASTIITPNLSIESEYVKDFIEPLKDDFGSLTILCKKFAENENVGLKLKTTNNQKNSSGFRPDSSNVSLLLQGKPLDFSHPSVDFIANYPKDDTYKTQLFSKYFLPMKSELKIFLENVGKDQKTVLIILWEAIKQNLTTDADIAVLCLSKMFALLTKDEFLKRLQELKAADVMELISHGLWKETQKNVNKEDSLEFINKELQLISLKFIKEERKRYKYEEFKKFVSIHLQEIFFSDVEKFQLWDSFLAQEIDREKFLDLFNEQLIPLMPKIDLEIFENSYLIKYLKSSFPIVFLGLQDVLSNRNFSKLCLVSSDLKINNATTNKLYLNFLESQSPTYESSQDLLIDTINRSIDLKTTVLKIQDLSDVYQWFYKKKPGLFDNLSKLYSTNPSWSDWEELASFLYPDDHNQENRVYFLDKIVAQKFTAEVLKTWFNLLKSEPNNPKIKESFLNGKTWKNLRDETIKNMYCYLTTEVPDYVSKLIQWASEKSRFDLINGKLTESAIEIWENNKTIDQQTWQILMFSPVQANLSNEKRFRMRIADLLCEPNSLSLTNNVEIKSQNISKERQNKSESQQKKPRDLFKKYTAHKTIQENVSSTDDPLTNSTSTQMSNNNQNEGKVNESRRDLPLYNKEQKTLHLLTELARKKINKFKDDPEKIEGFLELCETFEIKILEVLVEVDLKNCPGVFFKYLHSKNYDRNSTEYIRCFEKMLSQIQSNTKERDKIIDFVRDIGKNMIGEGDKELRELAVDSLASWARQGLK
>NC_008312.1|WP_011611526.1|2921965_2923147_+|hypothetical-protein
MVQEQQRQKNTRIKLGIWGTSSAGKTVYMLMLYHYLQRSKRKDRFLVKAGNEQTDKFLKKHLISRIYKGEFPSTTTKEDKYNSYSYKLKRNNSDTIVELTFLDLSGEIWKSRGYKVKTNNKKNEDVSVAKYLTQCHGILILLSPLKEDYPPKNSYFSLLEGLFRLMLREIPESEFKLEQYVVFGITKADHDEIYQRTIDRNFYQLIMEIIGPQASLEGLESYFHLEIVEEKDGTKRVNVNGENNRCCFLPISPFAKYYDEDGGKMISPVIENKTEEEPRANESQQEPPKAAGKRQEKQREDPFKKNLGKKQKNNDDYETPSTADNSEGGQREGHSSDNDDYDTPSTTNDDEPNQKQGKYKIDTRVEWRPQNVVEPIEWLIQRIENHPPKIFDE
>NC_008312.1|WP_011611525.1|2919565_2921767_+|hypothetical-protein
MPEINDIINNRKANATTAIKKKEDLEELERKIKELQRLRPEIIKAPGITSVVSERLEKVDLQGILDIITQERELWGRIEKRLNRDTINIAVVGLARQGKSTFLQQITLLTDAEIPASDGQPCTTTQSNIYHSPNESYGRVYFHSKSSFLEEVIIPYFKKLGFTSFPQRIEDFGRAQLPYLRENFSANDQSIYNHLKDEYYRHFSDYSHLLKNEKHVQKIRQDEIKEYVSQKYDLASQPTLFHHLAVEKVEIFCPFPNRGVEKIAVIDLPGLGDTRLGDAERMIKALAEDTDFILFIRKPNATGDFWGQRDVDLYDAAHQALEDKLPLEQWSFMLLNYDGENGRACQDFQNTIKSKGIHVKEDLQSNCKNSTSAKEVLTKILTYLERNLVRLDKQYMSSTYQQSFKRQQQVKLELQGLEQAIASYGDINAQYVVLRDKFVLQLYNDIEKFREEKREELDTSNPEFKAEVDAAINRCQQEFNIPDLERLNSWARKDGINAVYFRAKQQMRPGILKNFHLMETGLKAAVDQTKLELANILIQLGIGNIVKDNGLEFFPAMVEILNKSSSLPNLRFAFEFIDSFEVTYKGIIQYRVWKEIVDILPPNTMTFTKVSDNINNGDLSPNTIDFTKASDNMNLVVHDLQKLHQKAIEVCEEILDDIGIYFNNGRISMVEEFADYITRAEGVQGEWDIFLSNNRSKVWPELKEMEEQEQLRKYWLSLVQEALAINEQIKLSF
>NC_008312.1|WP_081432422.1|2918932_2919043_+|universal-stress-protein
MVIGYRGHSILSATVLGGVSSYMIHRAHCSVHILRG
>NC_008312.1|WP_081432538.1|2947741_2950771_+|hypothetical-protein
MTSISDSSLSDFSNSNFTIKPEDFITVSSPDGGNTLEPGKTYTINWRDNIDENVKLELYKAGSFFGNISSSTASNGSYSWAVPTSLTSGSDYQVKITSISDSSLSDLSNSNFTIKPEDFITVSSPDGGNTLKRGKNYRITWRDNIDENVKVELYKAGFLFGTISSSTESDGSYSWAVPTSLSTGNDYQVKVTSISDGSLSDFSNSNFTIKPEDLAKISIGDTKITEGNTNKAAKFKVTLDNPTTETVKVNYTTANQTAKVNQDYKLTKGTLTFRPGETNKTITVPILGDKRDEAEEKFNLNLSRPRNAKLKDAQAIGTIVDNDQPPQISIGDAKVTEGNKGKKNMEFEVKLNDPSGKTVKVSYGTVEGSAKSGKDYQKTSGVLTFKPGQRKKILNVPILGDTRDEKNENFQVKLSGAKNAKLSDKNAVGVIRDNDETVPQISIGDAKVTEGNKGKKNMEFEVELNKGSSKTVKVSYGTVDGSAKSGKDYQKTSGVLTFKPGQRKKILNVPILGDTREEKNENFQVKLSGAKNAKLSDKNAVGVIRDNDETVPQISIGDAKVTEGNKGKKNMEFEVELNKGSSKTVKVSYGTVEGSAKSGKDYQKTSGVLTFKPGQRKKILNVPILGDTRDEKNEQFQVKLSGAKNAKLSDKNAVGVIRDNDETVPQISIGDAKVTEGNKGKKNMEFEVELNKGSSKTVKVSYGTVDGSAKSGKDYQKTSGVLTFKPGQRKKILNVPILGDTRDEKNENFQVKLSGAKNAKLSDKNAVGVIRDNDEIIGKTPQISIKDTKITEGKKGEKDMKFEVKLDKSSSQIVRVNYETVDGSAKAGKDYEKKKGVLKFQPGETKKTVNISILGDTVDEKNENFRIKLSGAKNANLSDKNAIGMIRNNQVPESFKDAVDLGILSSEQTVVVDDIGFATGPVNRNTEDYFCFKVEKEGLVSIFVDGFIQDLGIKLYGDDESLLNQSNEKGNTTKEKINTILDPGVYYLKVFPLGVAATEYKLRVNIVDS
>NC_008312.1|WP_011611535.1|2954959_2955835_+|M48-family-metallopeptidase
MALTKTQLIGLKANHFRHPLDLEATNALKQLPGIDLLVRQLLSPLGEQFFYMENIASSVLVSEAQLPNLHKTLLDACQALDIEPPQLYIRQNPVPNAYTFAMRGKQPFIVVHTSLIELLNLEEIQAVLGHELGHLKCEHGVYLTLGNLIVLAAGQISTWGGIIAQSLQSKILEWLRCAEFSCDRAALLATQNSQVVVSALMKLAGGSPTISPQLNVDAFLAQARAYNELSNTEVGEVLKEVQTAQLTHPLPVLRAKEIDMWASSKKYQDILQNLAKDVYNNQRIKGGWRNW
>NC_008312.1|WP_044137313.1|2956693_2956984_-|hypothetical-protein
MNALWLKILKTAYRKDPVVSFVVTMGAVDAVIGGVESSWSLFFLGMGTVGVAIILRLYLLKGSHIEQSSAVPEYYLPPNSSRPQLPILNINKKHLP
>NC_008312.1|WP_011611537.1|2957063_2957879_-|helix-turn-helix-domain-containing-protein
MVQKAYKFRFYPTPEQEILLLRILGCIHLIYNKALATRTQAWHEHPERVSYKQTSAILTSWKKPEYLSFLPEVSSVVLQQSLRYLKTASNNLFSGHTKYPNSKKKRNVGSATFTKSAFKCKDGQVYLAKYAEQLYIRWSRQLLLGCIPSTIAISDANWGELVKQLEYKAQWYSRTLIKIDRYFPSSKRYSNCIHIVEKLSLNIRQWDCPESASHHDSYLNASINILATGQAVSVWVATVRPEESKSRRASTMKQKALNIDELGIFRKCLVG
>NC_008312.1|WP_011611538.1|2958688_2958859_-|hypothetical-protein
MKQPQPTNTPNLDEPKFGFNQYAERLNGRAAMIGFVLTLAIEYFTGEGLLSWLGLN
>NC_008312.1|WP_011611539.1|2959028_2959595_+|DUF3611-family-protein
MSNSLDSPSSLPPAVEQVAKALRLGGWICFWVQLVLGMVSGIIFIFAVGLLSQNTGAGTGGGLFFAVCSLVVLGFSIFLSFRYTRLARQLRSQISSLRPSRADTTQKVKRTLIINLVGMSLALLGGEAIGGILLGKSLVSKSFVFNPTELEKFTLDIFILLGNTHIIVAHFIGIIVGLFLLDRVYNKQ
>NC_008312.1|WP_011611540.1|2960959_2961700_+|helix-turn-helix-domain-containing-protein
MSTNLATTIELETSTESIILSRNSDNTDTNLSENNYNLSQEFEPKRYLLKWNKKPTKAEQEALLLEERNTYLQELGEKLQKARKMRCLSIKQIHKQTFVPLHYIEAIEKGETEKLPEDIYLRGFIFHLGNALGFDGVTLAAALPISNSLQGLIPSWSESNKGFGFYLHPAYLYLGYAALIAGAVGGLNWISQQPSPEANLIRKTIEPPNLAAHSNQHLETTQRPGLKYTKDSLVVGSDIAPPETMI
>NC_008312.1|WP_011611541.1|2961696_2962806_-|glutamate-5-kinase
MNTIVIKIGTSSLTNSETGNLALSTISSLIETIINLRQQGYQVVLVSSGAVGVGCDILGLTKKPRNISMKQAIAAVGQGQIMRVYNDLFSSLQQTVAQILLTKSDLSRRSSYVNAYNTFQQLFRLGVVPIVNENDTTAVEELNFGDNDTLSALVASLVEADWLFILTDVDRLYSADPRKNPDALPITLVGEIEQLKELKVQVGESVSGRGTGGMVTKIEAAKIATSAGVRTVITDGKVPTNIQKILNGESIGTQFEPQPEQVNGRKHWIANVLVPAGQLYLDQGAVKAISEYGKSLLAAGIIQVEGEFNSSDAVKLCNEKGQEIARGLVNYSSIELQKILGCRSENISDILGYVGAETVVHRNNLLLTN
>NC_008312.1|WP_011611542.1|2963590_2964661_+|Gfo/Idh/MocA-family-oxidoreductase
MSTLYSTDFTKNSQAKLLRVGVIGVGNMGQHHTRVLSLLKDTELVGVADINVERGLDTASKYGVRFFEEYQELLPHVDAVCVAVPTLQHYAVGMTCLKAGVHVLMEKPIAASIGEAEFLVNTAAETNRILQVGHIERFNPAFQELSKVLKTEELLALEAHRMSPYSHRANDVSVVLDLMIHDIDLLLELVAAPVVKLTASGSSASSSGNLDYVTATLGFANGIVATLTASKVTHKKLRSIVAHCKNSLTEADFLNNEILIHRQTTGDYVTDYGQVLYRQDGLIERVYTSNIEPLHAELEHFVYCVGGGNKPSVGGEQALKALRLGSLIEKIAIDDLAYHPVDSEFNLLNNSMLKVG
>NC_008312.1|WP_011611543.1|2965670_2966024_-|hypothetical-protein
MPLIKVKTSVAQLEKDKIDNLLKQLSSSMAKHFSKSESYVMTAFESDIPMTFGGNSDEPTCYIEIKSIGSMKPNQTKEMSQDFCEQINKTLGVPKNRIYIEFSDAQGYLWGWNSSTF

Crispr_ID: NC_008312_24

• CRISPR_ID: NC_008312_24
• CRISPR_location: 3021220-3021456
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 3 spacers

Consensus repeat of NC_008312_24

Consensus_repeat	Method
GCCTGAAGCGGAATTAATGGAAAC	CRISPRCasFinder

spacers of NC_008312_24

>24.1|3021244|48|NC_008312|CRISPRCasFinder
TATTCTATCAACTCCCTGAATAGGCTAATTATACTCCGCCCCAGCTTT
>24.2|3021316|39|NC_008312|CRISPRCasFinder
GTTAAGCACCTGCCTCCTTTTTGGTTCCCCCCCAGCTTT
>24.3|3021379|54|NC_008312|CRISPRCasFinder
CTGTCCTCTAAATACGGATCAAAATAATCACCTTTAACGTTTATCCCCAGTTTC

CRISPR arrays and Neighbor proteins around NC_008312_24

CRISPR arrays

The CRISPR arrays of NC_008312_24

>merge|NC_008312|24|3021220-3021456|CRISPRCasFinder
ACCTAAAGCGGAATTAATTGGAAATATTCTATCAACTCCCTGAATAGGCTAATTATACTCCGCCCCAGCTTTGCCTGAAGCGGAATTAATAGAAACGTTAAGCACCTGCCTCCTTTTTGGTTCCCCCCCAGCTTTGCCTGAAGCGGAATTAATGGAAACCTGTCCTCTAAATACGGATCAAAATAATCACCTTTAACGTTTATCCCCAGTTTCGCCTGAAGCGGAATTAATGGAAAC

>NC_008312|24|19|3021220-3021456|CRISPRCasFinder
ACCTAAAGCGGAATTAATTGGAAA	TATTCTATCAACTCCCTGAATAGGCTAATTATACTCCGCCCCAGCTTT
GCCTGAAGCGGAATTAATAGAAAC	GTTAAGCACCTGCCTCCTTTTTGGTTCCCCCCCAGCTTT
GCCTGAAGCGGAATTAATGGAAAC	CTGTCCTCTAAATACGGATCAAAATAATCACCTTTAACGTTTATCCCCAGTTTC
GCCTGAAGCGGAATTAATGGAAAC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_008312.1|WP_155994380.1|3020410_3020563_-|hypothetical-protein	unknown	unknown	unknown
NC_008312.1|WP_011611568.1|3006412_3007297_-|sugar-kinase	unknown	unknown	gnl|CDD|238920
NC_008312.1|WP_011611583.1|3033920_3034799_-|lipoyl-synthase	unknown	unknown	gnl|CDD|235493
NC_008312.1|WP_011611571.1|3014152_3014392_-|hypothetical-protein	unknown	unknown	unknown
NC_008312.1|WP_011611567.1|3005399_3006068_-|hypothetical-protein	unknown	unknown	unknown
NC_008312.1|WP_011611579.1|3027868_3028264_-|transcriptional-repressor	unknown	unknown	gnl|CDD|223806
NC_008312.1|WP_011611572.1|3015716_3016298_+|hypothetical-protein	unknown	unknown	unknown
NC_008312.1|WP_011611581.1|3028863_3029559_+|phosphoribosylformylglycinamidine-synthase-subunit-PurQ	unknown	unknown	gnl|CDD|235140
NC_008312.1|WP_011611582.1|3031976_3033209_-|RNA-polymerase-sigma-factor-SigC	unknown	unknown	gnl|CDD|236067
NC_008312.1|WP_011611577.1|3025996_3026461_+|NfeD-family-protein	unknown	unknown	gnl|CDD|224501
NC_008312.1|WP_044136637.1|3022167_3022371_-|hypothetical-protein	unknown	unknown	unknown
NC_008312.1|WP_011611580.1|3028347_3028611_+|phosphoribosylformylglycinamidine-synthase-subunit-PurS	unknown	unknown	gnl|CDD|235659
NC_008312.1|WP_011611573.1|3016553_3017336_+|ABC-transporter-permease	unknown	unknown	gnl|CDD|226218
NC_008312.1|WP_011611575.1|3023055_3023277_-|ferredoxin--nitrite-reductase	unknown	unknown	gnl|CDD|367263
NC_008312.1|WP_011611574.1|3018029_3019724_-|tetratricopeptide-repeat-protein	unknown	unknown	gnl|CDD|274350
NC_008312.1|WP_011611576.1|3023399_3025337_-|protein-serine/threonine-phosphatase	unknown	unknown	gnl|CDD|237756
NC_008312.1|WP_155994379.1|3010873_3013543_-|glucosidase	unknown	unknown	gnl|CDD|367389
NC_008312.1|WP_081432539.1|3008679_3010032_+|DNA-phosphorothioation-system-restriction-enzyme	unknown	unknown	gnl|CDD|274978
NC_008312.1|WP_011611578.1|3026641_3027607_+|SPFH/Band-7/PHB-domain-protein	unknown	unknown	gnl|CDD|223407
NC_008312.1|WP_011611564.1|3003397_3003745_+|hypothetical-protein	unknown	unknown	unknown

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_008312.1|WP_011611568.1|3006412_3007297_-|sugar-kinase	gnl|CDD|238920	cd01945, ribokinase_group_B, Ribokinase-like subgroup B. Found in bacteria and plants, this subgroup is part of the ribokinase/pfkB superfamily. Its oligomerization state is unknown at this time. .	1.64929e-128
NC_008312.1|WP_081432539.1|3008679_3010032_+|DNA-phosphorothioation-system-restriction-enzyme	gnl|CDD|274978	TIGR04095, type_III_restriction_protein_res_subunit, DNA phosphorothioation system restriction enzyme. The DNA phosphorothioate modification system dnd (DNA instability during electrophoresis) recently has been shown to provide a modification essential to a restriction system. This protein family was detected by Partial Phylogenetic Profiling as linked to dnd, and its members usually are clustered with the dndABCDE genes.	0
NC_008312.1|WP_011611577.1|3025996_3026461_+|NfeD-family-protein	gnl|CDD|224501	COG1585, COG1585, Membrane protein implicated in regulation of membrane protease activity [Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion].	5.06252e-22
NC_008312.1|WP_011611579.1|3027868_3028264_-|transcriptional-repressor	gnl|CDD|223806	COG0735, Fur, Fe2+/Zn2+ uptake regulation proteins [Inorganic ion transport and metabolism].	1.38377e-31
NC_008312.1|WP_011611581.1|3028863_3029559_+|phosphoribosylformylglycinamidine-synthase-subunit-PurQ	gnl|CDD|235140	PRK03619, PRK03619, phosphoribosylformylglycinamidine synthase subunit PurQ.	6.33977e-153
NC_008312.1|WP_011611582.1|3031976_3033209_-|RNA-polymerase-sigma-factor-SigC	gnl|CDD|236067	PRK07598, PRK07598, RNA polymerase sigma factor SigC; Validated.	0
NC_008312.1|WP_011611580.1|3028347_3028611_+|phosphoribosylformylglycinamidine-synthase-subunit-PurS	gnl|CDD|235659	PRK05974, PRK05974, phosphoribosylformylglycinamidine synthase subunit PurS; Reviewed.	8.87238e-39
NC_008312.1|WP_011611573.1|3016553_3017336_+|ABC-transporter-permease	gnl|CDD|226218	COG3694, COG3694, ABC-type uncharacterized transport system, permease component [General function prediction only].	6.14607e-88
NC_008312.1|WP_011611575.1|3023055_3023277_-|ferredoxin--nitrite-reductase	gnl|CDD|367263	pfam02941, FeThRed_A, Ferredoxin thioredoxin reductase variable alpha chain.	2.60397e-34
NC_008312.1|WP_011611574.1|3018029_3019724_-|tetratricopeptide-repeat-protein	gnl|CDD|274350	TIGR02917, TPR_domain_protein, putative PEP-CTERM system TPR-repeat lipoprotein. This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.	2.16084e-26
NC_008312.1|WP_011611576.1|3023399_3025337_-|protein-serine/threonine-phosphatase	gnl|CDD|237756	PRK14559, PRK14559, serine/threonine phosphatase.	3.56753e-65
NC_008312.1|WP_155994379.1|3010873_3013543_-|glucosidase	gnl|CDD|367389	pfam03200, Glyco_hydro_63, Glycosyl hydrolase family 63 C-terminal domain. This is a family of eukaryotic enzymes belonging to glycosyl hydrolase family 63. They catalyze the specific cleavage of the non-reducing terminal glucose residue from Glc(3)Man(9)GlcNAc(2). Mannosyl oligosaccharide glucosidase EC:3.2.1.106 is the first enzyme in the N-linked oligosaccharide processing pathway. This family represents the C-terminal catalytic domain.	1.70361e-08
NC_008312.1|WP_011611583.1|3033920_3034799_-|lipoyl-synthase	gnl|CDD|235493	PRK05481, PRK05481, lipoyl synthase; Provisional.	0
NC_008312.1|WP_011611578.1|3026641_3027607_+|SPFH/Band-7/PHB-domain-protein	gnl|CDD|223407	COG0330, HflC, Membrane protease subunits, stomatin/prohibitin homologs [Posttranslational modification, protein turnover, chaperones].	3.49457e-60

Protein sequences

>NC_008312.1|WP_155994380.1|3020410_3020563_-|hypothetical-protein
MKTPIEVMSAFQSLQNQYKNICIPHKKVKGRQLREKQKLENQKLRIVKDS
>NC_008312.1|WP_011611574.1|3018029_3019724_-|tetratricopeptide-repeat-protein
MSKTHAKSSEKLTFLTTLNTKNNQTISSSKGIFSIFSAFPEYDRGNRLYEMGRYESAIPYYENAVKIKPDWAIGWLKLAEALSKLQKYEQAVEAYKRSLSLKQNAHQAWHSYGVVLSNLKQYEQAIACFDKAIKINPNDYQSWFNKAIILSELKQDLPAIYCYKEALKIQPMKGEIWYGQGQALLNVQKYAEALAAYDCAAKLQPDNYDIWFKRGLALFQTQRYAEAVISYGHAIELQPENYLGWFNLGIAQSKLHKYHDAVSSFNKAIKLNPDDYEAWYYKGLALKNHWKEGGVACLDKAINFNPNLPEIWISRGYILLDLFKYREALESFNKAITINSNYPESWLGRGKAWMALGKYNEALIAYGNAVSIEPYFLEAWNCRGEALERVQNYDQALAAYDKVIKMSFEQGVSVAKVGLQRGAALEKLERYPEAIEAYNLVIEKQPNNFDGWLNRGLNLEKMANYEEAVLSYSRAISIWPSNYQAWLQLALMLEKLERLDEAIVAYNKIISLRPGNHETWLKRGLILERLGYVQEAVSSYKIVLEIKPDYHEAIERKKRLELTV
>NC_008312.1|WP_011611573.1|3016553_3017336_+|ABC-transporter-permease
MKRYLQVLKLFWSAAIAAELEYRFNFMIAAISSIGGLLGSLFSLLLFYRTGYKFQGWNWEESLIILAIFTILQGLSATFLIPSLNRIVKQVQEGTLDFVLLKPISSQFLLSTRTISPWGILDIIFGGFLLEYAGSKLGLGISNYLLTILPMVCGIIILYSIWFILGSTSIWFVKIYNLTEVLRGLLGAGRYPIVAYPTAYRFFFTFLVPVAFLTTVPAQTILGKAGSTWILGSFVLAGGLFFASIQFWRLALRYYTSASS
>NC_008312.1|WP_011611572.1|3015716_3016298_+|hypothetical-protein
MKLKTKLYTDAVKEALLSLSDIEFYNTIHYWLERISKNYWETELLDEMQLALGYTLESGETLQSYKNWDELMCAEPDCKNVYLIAPSPLKLRRYLYQMDSHSFYENIIYLAGVAYTDGQIGEPPNAFCDGYEFMENLVANLRKNQPNQEINYPPQTIPIMNQIQSNEKLFQVSEYWRSYSGGKVTDFVLLTSN
>NC_008312.1|WP_011611571.1|3014152_3014392_-|hypothetical-protein
MRRNLPTIMGNSGSQGDATLTSLMAGKLLQVFFRMELLAKFTSVELREKTPKYEIILLAQRKTLCCSKSEMMLRNSVSQ
>NC_008312.1|WP_155994379.1|3010873_3013543_-|glucosidase
MNTQNHNILTQEEQRLEADLNHKAYWQRWGPYLSERQWGTVREDYSEDGSAWDYFSHEQSHYRAYRWGEDGICGISDNHQRLCFAIALWNGEDLMLKERLFGLTGTQGNHGEDVKEYYFYLDNTPSHSYMKALYKYPQAAFPYTELLTENQQRDGKSLEYELLDTGVFAENRYFDVFVEYAKATAEDILIKITVNNLASETKTLHLLPTLWFRNTWSWTQDSEKPILKKINHGLVEANHPTLGKRWLYFSETMELFFTENETNAQRLSGEKNTSPYVKDGINNYLVNGQKDAINPNMSGTKFAPHYLLELKPGETKTIKLRLANSSEIRQPFDAKFDDTFQRRIQEADEFYQRISPCKMKDELRNIQRQAFAGLLWTKQYYHYVVEDWLKGDFQEPSILENRKNIRNSEWIHLFNDDIISMPDKWEYPWYAVWDLAFHTIPLAIIDPNFAKHQLDLITREWYMHPNGQLPAYEWNFNDVNPPVHAWGTWRVYQIEKEVYGRQDRKFLERVFQKLLLNFTWWVNQKDIEGNNVFEGGFLGLDNIGVFNRSSELPTGGHIEQSDGTSWMAMFCLDMLKIALELALENDVYEDIASKFFEHFLYIVDAMNHLGPGGTQLWDETDNFYYDVLHEPGKEDIHLKVRSIVGLIPLFAVAIIDSETLQKLPKFKKRVNWFMQNRVDLSANIACLEACGIESERLLAIVSPERLKIILEKMLDENEFFSDYGVRSLSRYHAENPYIFYADEDEYRVDYEPAESVSAMFGGNSNWRGPIWFPINHLMIESLQRFHNYLGDDFRVECPTGSGQMMNLWEVSLEIEARLINIFLKDKNGKRPVYGDTEMFQNDDHWQDLILFYEYFHGDKGAGLGANHQTGWTGLVAKLIQQRSEYSCEI
>NC_008312.1|WP_081432539.1|3008679_3010032_+|DNA-phosphorothioation-system-restriction-enzyme
MPSHLTLRPYQEQAINNWFANRGRGILKMATGTGKTITALAIATQLYQKISLQVLIVVCPYRHLVTQWGRECEKFAFQPILAFENVNAWQNQLSTILYNIHSGNKKFISIITTNSTFISDSFQSQLKYFPEKTLIIGDEAHHLGSPKLEKSLPKNFGLRLALSATPERYFDSQGTTAILDYFGQVLQPELTLANAIQQGALARYLYYPILVELTESESRDYVKLTSKIGWALLLSEKRNVKIEKEDLTALLMQRSRLIASAKNKLTALKKLMLNRLQTTHTLFYCGDGWVEKNNISNLRQMEAVVKVLGSELGYRVNTYTSETSIKTREKLRKQFENGELQGLVAIRCLDEGIDIPAIKNAVILASSQNPRQFIQRRGRILRPHSSKERATLFDMIVLPPDMGRSTLAIERNLLKKELKRFLEFADLADNAGEARVKLLSIQKKYGLLDI
>NC_008312.1|WP_011611568.1|3006412_3007297_-|sugar-kinase
MTKTGLFVGLITLDLVYLTATYPDNNQKVVAANYAVTAGGPATNAAVTFSYFNNQTTLIGVLGNHPITHLIKADLEKHNVRIQDLDKNRSEPPPVSSIITTQDTGDRAVISINATKSQISKELISSEILHNIDIVLIDGHQMAASLEIAQLAKSKNIPIVIDGGSWKLGFEEILPFVDYAICSANFYPPNCESQEEVFEYLASQNIRHIAITQGEKSIKYLNKGKFGNIAIPKVNVVDTLGAGDIFHGAFCHYIFDGEFTEALRNAANIAAHSCQYFGTRNLFLVGENPDLSQD
>NC_008312.1|WP_011611567.1|3005399_3006068_-|hypothetical-protein
MNNLNEYLTAIQTLLKNSDFWQKVAIAIISAFSVALFNYFSSNKQRQDQAMELSYTTNILSILEFKKDIDQKNISILYGEDYEVVDLYVISCDIENTGKKVIKNQEITFEFISTNVGVLEQFFEPPLNDNAMGIEEIEIEDIKQGEVKKRYLIREILPKRKVGFRFLSGRQTQEDEVPKLFCSIQDISKVELIPRTYKGERDEIAIIMNLLSQFLMIYTNKN
>NC_008312.1|WP_011611564.1|3003397_3003745_+|hypothetical-protein
MMSAIFLFFVGLVFVIWLRHQPKEIYLKNEISRFTQSRPSLHGDKTSNGNVNSGEAVVMATKQKTSRSRHRPGAVSGDKNCYPNAERAQHRTARRARVPYTSFCEGETEFRQDYY
>NC_008312.1|WP_044136637.1|3022167_3022371_-|hypothetical-protein
MANKSPWRLKFDGKIHSWKRGAIAYHQFQIFWHLAIYNCPDPNLFFFEVTQTFLLIKGKQFQELKVL
>NC_008312.1|WP_011611575.1|3023055_3023277_-|ferredoxin--nitrite-reductase
MKLGDRVRVNSSVVVYIHPEHKGQPFDIKDHEGEVINIINEWKGRPVSANLPILVKFTKFKVHLKEEELEIIS
>NC_008312.1|WP_011611576.1|3023399_3025337_-|protein-serine/threonine-phosphatase
MINSAPIIHCPNINCSSVSHSWDQEECEACQTKLIYRYLWAVAPKVEISVGELLGDRYYVVAPQVWLDTKPGEPPFMHEEFPDYIMPYLRLYPERLHTPDVYGFYQYGEETYPTDILLLDNVPLDSKGNLLPSLVEAWPTASPVRQVYWLWQMMQLWKPLSEERVAFSLLTNNLRVEDWRLRLLELNLETRKTKLRDFKIFWSNLLPTAHPNVQQPLTEICHMISDIGESLEAIAPKLNQLLLEQAAKLPLKSDIMGATDTGPVRMHNEDCCYPTEEDLNSNQLVPNLAIICDGVGGHDGGEVASQLAVQSIKKLVQNLLIEVEQQEELTSPNLVNKQLEEIIRVVNNMIATENDEQGRESRQRMGTTLAMALQLPQQVKPSPESSPNNAHELYIVHVGDSRAYWLSRNTCQLLTVDDNVASREVGLGHCLYWQGLKRRDGGALTQALGTRDGEFIYPTIQRFLIEQEGILLLCSDGLSDNNWVENSWAEYASKVFQGEISLKQGVESLIELANHKNGHDNTSVVLVHYRLSPEKLILSNIPTVTTPEKEILMTELSEASKELLYNNDEEVSEAESEFQLEPVQNFFWLKPWMCMMGVLFILLVGAIISVWRNWENFQSTPRDSPAPWESPMRPEPSETRISPSS
>NC_008312.1|WP_011611577.1|3025996_3026461_+|NfeD-family-protein
MLLNPTIFWLLAGATLCFLEFFVPTAFVEFMMGLSAFVVALVSLLIPSVSLQVALWMIFSVASIFAFRYLLPHRKIAIIADSKEGETLTEILPGQPGRVLYEGNSWRAKCDDQDIMIPAQEKVIVLRREGNTLFILPENLLNSSVYLPNQNQLK
>NC_008312.1|WP_011611578.1|3026641_3027607_+|SPFH/Band-7/PHB-domain-protein
MQQFFLLVFLVLGGSSLAGSVKVINQGNEALVETLGRYNGRKLDAGLKLIIPFLDKISYQETIREKVLDIKPQPCITRDNVAISVDAVVYWRIMDMEKAYYKVENLQSAMTNLVLTQIRAEMGKLELDQTFTARTEINEVLLRELDIATDPWGVKVTRVELRDISPSKAVQDSMELQMTAERKKRAAILTSEGERDSAINSARGRAESQVLDAQARQKATVLEAEAQQKAIVLKAQAERQSQVLKAQATAEALEIITKTLRKDPNAKEALEFLLAQNYLDMGQKIGTSESSKVMFMDPRNIPATLEGMRSIVTDNKNSVSI
>NC_008312.1|WP_011611579.1|3027868_3028264_-|transcriptional-repressor
MKTKRTHSQERILKLLKNQKRSLSAQDIYLKLRRYDRPLGLATIYRSLDALKKEGVVIVRTLVNGESVYSCLQQDQYYLNCVKCGTSIPINKCPVYNLEDKLQQSYKFKIFYHTLEFFGLCERCTLTEDIS
>NC_008312.1|WP_011611580.1|3028347_3028611_+|phosphoribosylformylglycinamidine-synthase-subunit-PurS
MIKKYQVYIYVTLRPSVLDPAGTAVKSGLAQMGHKNLEQIRIGKYIELKLNATDEETAREQVELICDQLLANPVIENYRFELNEVKI
>NC_008312.1|WP_011611581.1|3028863_3029559_+|phosphoribosylformylglycinamidine-synthase-subunit-PurQ
MKFGIIIFPGSNCDRDVAWVTQGLLGQPTRMVWHQEEDISDLDVIVIPGGFSYGDYLRCGAIARFSPVMKATITHAQKGKLVLGICNGFQILTEIGLLPGVLVRNHKLNFICNQTYIRVENSNTPWTSAYRTKEIISLPIAHGEGCYYVDVDTLQELENNRQILFRYCTKNGGISPEANPNGSLNNIAGICNRQGNVLAMMPHPERASDPILGNTDGMKLFKGLLMDVVRI
>NC_008312.1|WP_011611582.1|3031976_3033209_-|RNA-polymerase-sigma-factor-SigC
MITTSEIYPYTEDTLQSNNLQNECSEHLGQTINELTIEDKKVDSSQINTNYSGRDSVRSYLQEIGRVDLLQRDQEVSTAQKVQRYVHLLELRNKAAEQEQEIQRYVEMIKIRDRLAARLGHKPSFERWLKAGNLSMAELKEIIAVGKLRWAKLTGLNVKELEQIQTEGIEARHQMISTNLRLVVSIAKKYQNRGVELLDLIQEGTLGLERAVEKFDPQRGYRFSTYAYWWIRQGITRAIATQSRTIRLPIHVSEKLNKIKKVQQKIFQEKGYTAKVEEIARELKITAAQVREVLVKIPHSVSLETKVGRDRDTELGELLETKDASPEEMLIRESLVQALKELLLDLTQRERYVITMRYGLEDGRACSLSEIASALKLSRERVRQIEVKALHKLRQPKFRNQIQDYLESLN
>NC_008312.1|WP_011611583.1|3033920_3034799_-|lipoyl-synthase
MVVKPDWLRVKAPQWQRVGTVKEILRDLSLKTVCEEASCPNIGECFNAGTATFLIMGPACTRACPYCDINFEKKPQPLDVNEPKQLAEAVKRLRLNHVVITSVNRDDLTDGGATQFAKCISQVRAISPQTTIEVLIPDLCGNWQALEIILNAKPEVINHNTETVQRLYRRVRPQGNYHRTLELLKRARELAPEIYTKSGIMVGVGETDAEVQEVMKDLRVVDCDILTIGQYLQPSLKHLPVDTFIKPEQFDQWKKIGLSMGFLQVVASPLTRSSYHAEEVKELMVNYPKTKS

Crispr_ID: NC_008312_25

• CRISPR_ID: NC_008312_25
• CRISPR_location: 3030162-3030266
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NC_008312_25

Consensus_repeat	Method
AAAATGTTATTGAATCTATTCATTTTCAGC	CRISPRCasFinder

spacers of NC_008312_25

>25.1|3030192|45|NC_008312|CRISPRCasFinder
TCTGGATCCTGATGATGATTTCTGAGTCCTAAAAAATTCCCCTTA

CRISPR arrays and Neighbor proteins around NC_008312_25

CRISPR arrays

The CRISPR arrays of NC_008312_25

>merge|NC_008312|25|3030162-3030266|CRISPRCasFinder
AAAATGTTATTGAATCTATTCATTTTCAGCTCTGGATCCTGATGATGATTTCTGAGTCCTAAAAAATTCCCCTTAAAAATGTTATTGAATCTATTCATTTTCAGC

>NC_008312|25|20|3030162-3030266|CRISPRCasFinder
AAAATGTTATTGAATCTATTCATTTTCAGC	TCTGGATCCTGATGATGATTTCTGAGTCCTAAAAAATTCCCCTTA
AAAATGTTATTGAATCTATTCATTTTCAGC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_008312.1|WP_011611590.1|3043879_3046588_+|cyanophycin-synthetase	unknown	unknown	gnl|CDD|273950
NC_008312.1|WP_011611591.1|3047083_3047227_-|high-light-inducible-protein	unknown	unknown	gnl|CDD|177653
NC_008312.1|WP_011611585.1|3036359_3037823_-|peptidoglycan-binding-protein	unknown	unknown	gnl|CDD|225943
NC_008312.1|WP_155994380.1|3020410_3020563_-|hypothetical-protein	unknown	unknown	unknown
NC_008312.1|WP_011611582.1|3031976_3033209_-|RNA-polymerase-sigma-factor-SigC	unknown	unknown	gnl|CDD|236067
NC_008312.1|WP_011611577.1|3025996_3026461_+|NfeD-family-protein	unknown	unknown	gnl|CDD|224501
NC_008312.1|WP_011611579.1|3027868_3028264_-|transcriptional-repressor	unknown	unknown	gnl|CDD|223806
NC_008312.1|WP_011611584.1|3035690_3036203_+|transcriptional-repressor	unknown	unknown	gnl|CDD|366663
NC_008312.1|WP_011611581.1|3028863_3029559_+|phosphoribosylformylglycinamidine-synthase-subunit-PurQ	unknown	unknown	gnl|CDD|235140
NC_008312.1|WP_011611587.1|3040868_3041552_-|tRNA-(guanosine(37)-N1)-methyltransferase-TrmD	unknown	unknown	gnl|CDD|234581
NC_008312.1|WP_011611592.1|3048339_3050928_+|DUF4912-domain-containing-protein	unknown	unknown	gnl|CDD|270371
NC_008312.1|WP_044136637.1|3022167_3022371_-|hypothetical-protein	unknown	unknown	unknown
NC_008312.1|WP_011611580.1|3028347_3028611_+|phosphoribosylformylglycinamidine-synthase-subunit-PurS	unknown	unknown	gnl|CDD|235659
NC_008312.1|WP_081432424.1|3039942_3040101_-|hypothetical-protein	unknown	unknown	unknown
NC_008312.1|WP_011611589.1|3042693_3043569_+|cyanophycinase	unknown	unknown	gnl|CDD|131124
NC_008312.1|WP_011611575.1|3023055_3023277_-|ferredoxin--nitrite-reductase	unknown	unknown	gnl|CDD|367263
NC_008312.1|WP_011611574.1|3018029_3019724_-|tetratricopeptide-repeat-protein	unknown	unknown	gnl|CDD|274350
NC_008312.1|WP_011611576.1|3023399_3025337_-|protein-serine/threonine-phosphatase	unknown	unknown	gnl|CDD|237756
NC_008312.1|WP_011611583.1|3033920_3034799_-|lipoyl-synthase	unknown	unknown	gnl|CDD|235493
NC_008312.1|WP_011611578.1|3026641_3027607_+|SPFH/Band-7/PHB-domain-protein	unknown	unknown	gnl|CDD|223407

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_008312.1|WP_011611590.1|3043879_3046588_+|cyanophycin-synthetase	gnl|CDD|273950	TIGR02068, Cyanophycin_synthetase, cyanophycin synthetase. Cyanophycin is an insoluble storage polymer for carbon, nitrogen, and energy, found in most Cyanobacteria. The polymer has a backbone of L-aspartic acid, with most Asp side chain carboxyl groups attached to L-arginine. The polymer is made by this enzyme, cyanophycin synthetase, and degraded by cyanophycinase. Heterologously expressed cyanophycin synthetase in E. coli produces a closely related, water-soluble polymer with some Arg replaced by Lys. It is unclear whether enzymes that produce soluble cyanophycin-like polymers in vivo in non-Cyanobacterial species should be designated as cyanophycin synthetase itself or as a related enzyme. This model makes the designation as cyanophycin synthetase. Cyanophycin synthesis is analogous to polyhydroxyalkanoic acid (PHA) biosynthesis, except that PHA polymers lack nitrogen and may be made under nitrogen-limiting conditions. [Cellular processes, Biosynthesis of natural products].	0
NC_008312.1|WP_011611585.1|3036359_3037823_-|peptidoglycan-binding-protein	gnl|CDD|225943	COG3409, COG3409, Putative peptidoglycan-binding domain-containing protein [Cell envelope biogenesis, outer membrane].	9.88981e-20
NC_008312.1|WP_011611574.1|3018029_3019724_-|tetratricopeptide-repeat-protein	gnl|CDD|274350	TIGR02917, TPR_domain_protein, putative PEP-CTERM system TPR-repeat lipoprotein. This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.	2.16084e-26
NC_008312.1|WP_011611582.1|3031976_3033209_-|RNA-polymerase-sigma-factor-SigC	gnl|CDD|236067	PRK07598, PRK07598, RNA polymerase sigma factor SigC; Validated.	0
NC_008312.1|WP_011611577.1|3025996_3026461_+|NfeD-family-protein	gnl|CDD|224501	COG1585, COG1585, Membrane protein implicated in regulation of membrane protease activity [Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion].	5.06252e-22
NC_008312.1|WP_011611579.1|3027868_3028264_-|transcriptional-repressor	gnl|CDD|223806	COG0735, Fur, Fe2+/Zn2+ uptake regulation proteins [Inorganic ion transport and metabolism].	1.38377e-31
NC_008312.1|WP_011611584.1|3035690_3036203_+|transcriptional-repressor	gnl|CDD|366663	pfam01475, FUR, Ferric uptake regulator family. This family includes metal ion uptake regulator proteins, that bind to the operator DNA and controls transcription of metal ion-responsive genes. This family is also known as the FUR family.	6.74369e-50
NC_008312.1|WP_011611581.1|3028863_3029559_+|phosphoribosylformylglycinamidine-synthase-subunit-PurQ	gnl|CDD|235140	PRK03619, PRK03619, phosphoribosylformylglycinamidine synthase subunit PurQ.	6.33977e-153
NC_008312.1|WP_011611587.1|3040868_3041552_-|tRNA-(guanosine(37)-N1)-methyltransferase-TrmD	gnl|CDD|234581	PRK00026, trmD, tRNA (guanine-N(1)-)-methyltransferase; Reviewed.	2.73719e-145
NC_008312.1|WP_011611592.1|3048339_3050928_+|DUF4912-domain-containing-protein	gnl|CDD|270371	cd13653, PBP2_phosphate_like_1, Substrate binding domain of putative ABC-type phosphate transporter, a member of the type 2 periplasmic binding fold superfamily. This subfamily contains uncharacterized phosphate binding domains found in PstS proteins that serve as initial receptors in the ABC transport of phosphate in eubacteria and archaea. After binding the ligand, PstS interacts with a cognate membrane transport complex comprised of two integral membrane domains and two cytoplasmically located ATPase domains. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis. The PstS proteins belong to the PBP2 superfamily of periplasmic binding proteins that differ in size and ligand specificity, but have similar tertiary structures consisting of two globular subdomains connected by a flexible hinge. They have been shown to bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap.	1.27277e-44
NC_008312.1|WP_011611580.1|3028347_3028611_+|phosphoribosylformylglycinamidine-synthase-subunit-PurS	gnl|CDD|235659	PRK05974, PRK05974, phosphoribosylformylglycinamidine synthase subunit PurS; Reviewed.	8.87238e-39
NC_008312.1|WP_011611591.1|3047083_3047227_-|high-light-inducible-protein	gnl|CDD|177653	PLN00014, PLN00014, light-harvesting-like protein 3; Provisional.	0.000911322
NC_008312.1|WP_011611589.1|3042693_3043569_+|cyanophycinase	gnl|CDD|131124	TIGR02069, cyanophycinase, cyanophycinase. This model describes both cytosolic and extracellular cyanophycinases. The former are part of a system in many Cyanobacteria and a few other species of generating and later utilizing a storage polymer for nitrogen, carbon, and energy, called cyanophycin. The latter are found in species such as Pseudomonas anguilliseptica that can use external cyanophycin. The polymer has a backbone of L-aspartic acid, with most Asp side chain carboxyl groups attached to L-arginine. [Energy metabolism, Other].	3.79352e-109
NC_008312.1|WP_011611575.1|3023055_3023277_-|ferredoxin--nitrite-reductase	gnl|CDD|367263	pfam02941, FeThRed_A, Ferredoxin thioredoxin reductase variable alpha chain.	2.60397e-34
NC_008312.1|WP_011611576.1|3023399_3025337_-|protein-serine/threonine-phosphatase	gnl|CDD|237756	PRK14559, PRK14559, serine/threonine phosphatase.	3.56753e-65
NC_008312.1|WP_011611583.1|3033920_3034799_-|lipoyl-synthase	gnl|CDD|235493	PRK05481, PRK05481, lipoyl synthase; Provisional.	0
NC_008312.1|WP_011611578.1|3026641_3027607_+|SPFH/Band-7/PHB-domain-protein	gnl|CDD|223407	COG0330, HflC, Membrane protease subunits, stomatin/prohibitin homologs [Posttranslational modification, protein turnover, chaperones].	3.49457e-60

Protein sequences

>NC_008312.1|WP_011611581.1|3028863_3029559_+|phosphoribosylformylglycinamidine-synthase-subunit-PurQ
MKFGIIIFPGSNCDRDVAWVTQGLLGQPTRMVWHQEEDISDLDVIVIPGGFSYGDYLRCGAIARFSPVMKATITHAQKGKLVLGICNGFQILTEIGLLPGVLVRNHKLNFICNQTYIRVENSNTPWTSAYRTKEIISLPIAHGEGCYYVDVDTLQELENNRQILFRYCTKNGGISPEANPNGSLNNIAGICNRQGNVLAMMPHPERASDPILGNTDGMKLFKGLLMDVVRI
>NC_008312.1|WP_011611580.1|3028347_3028611_+|phosphoribosylformylglycinamidine-synthase-subunit-PurS
MIKKYQVYIYVTLRPSVLDPAGTAVKSGLAQMGHKNLEQIRIGKYIELKLNATDEETAREQVELICDQLLANPVIENYRFELNEVKI
>NC_008312.1|WP_011611579.1|3027868_3028264_-|transcriptional-repressor
MKTKRTHSQERILKLLKNQKRSLSAQDIYLKLRRYDRPLGLATIYRSLDALKKEGVVIVRTLVNGESVYSCLQQDQYYLNCVKCGTSIPINKCPVYNLEDKLQQSYKFKIFYHTLEFFGLCERCTLTEDIS
>NC_008312.1|WP_011611578.1|3026641_3027607_+|SPFH/Band-7/PHB-domain-protein
MQQFFLLVFLVLGGSSLAGSVKVINQGNEALVETLGRYNGRKLDAGLKLIIPFLDKISYQETIREKVLDIKPQPCITRDNVAISVDAVVYWRIMDMEKAYYKVENLQSAMTNLVLTQIRAEMGKLELDQTFTARTEINEVLLRELDIATDPWGVKVTRVELRDISPSKAVQDSMELQMTAERKKRAAILTSEGERDSAINSARGRAESQVLDAQARQKATVLEAEAQQKAIVLKAQAERQSQVLKAQATAEALEIITKTLRKDPNAKEALEFLLAQNYLDMGQKIGTSESSKVMFMDPRNIPATLEGMRSIVTDNKNSVSI
>NC_008312.1|WP_011611577.1|3025996_3026461_+|NfeD-family-protein
MLLNPTIFWLLAGATLCFLEFFVPTAFVEFMMGLSAFVVALVSLLIPSVSLQVALWMIFSVASIFAFRYLLPHRKIAIIADSKEGETLTEILPGQPGRVLYEGNSWRAKCDDQDIMIPAQEKVIVLRREGNTLFILPENLLNSSVYLPNQNQLK
>NC_008312.1|WP_011611576.1|3023399_3025337_-|protein-serine/threonine-phosphatase
MINSAPIIHCPNINCSSVSHSWDQEECEACQTKLIYRYLWAVAPKVEISVGELLGDRYYVVAPQVWLDTKPGEPPFMHEEFPDYIMPYLRLYPERLHTPDVYGFYQYGEETYPTDILLLDNVPLDSKGNLLPSLVEAWPTASPVRQVYWLWQMMQLWKPLSEERVAFSLLTNNLRVEDWRLRLLELNLETRKTKLRDFKIFWSNLLPTAHPNVQQPLTEICHMISDIGESLEAIAPKLNQLLLEQAAKLPLKSDIMGATDTGPVRMHNEDCCYPTEEDLNSNQLVPNLAIICDGVGGHDGGEVASQLAVQSIKKLVQNLLIEVEQQEELTSPNLVNKQLEEIIRVVNNMIATENDEQGRESRQRMGTTLAMALQLPQQVKPSPESSPNNAHELYIVHVGDSRAYWLSRNTCQLLTVDDNVASREVGLGHCLYWQGLKRRDGGALTQALGTRDGEFIYPTIQRFLIEQEGILLLCSDGLSDNNWVENSWAEYASKVFQGEISLKQGVESLIELANHKNGHDNTSVVLVHYRLSPEKLILSNIPTVTTPEKEILMTELSEASKELLYNNDEEVSEAESEFQLEPVQNFFWLKPWMCMMGVLFILLVGAIISVWRNWENFQSTPRDSPAPWESPMRPEPSETRISPSS
>NC_008312.1|WP_011611575.1|3023055_3023277_-|ferredoxin--nitrite-reductase
MKLGDRVRVNSSVVVYIHPEHKGQPFDIKDHEGEVINIINEWKGRPVSANLPILVKFTKFKVHLKEEELEIIS
>NC_008312.1|WP_044136637.1|3022167_3022371_-|hypothetical-protein
MANKSPWRLKFDGKIHSWKRGAIAYHQFQIFWHLAIYNCPDPNLFFFEVTQTFLLIKGKQFQELKVL
>NC_008312.1|WP_155994380.1|3020410_3020563_-|hypothetical-protein
MKTPIEVMSAFQSLQNQYKNICIPHKKVKGRQLREKQKLENQKLRIVKDS
>NC_008312.1|WP_011611574.1|3018029_3019724_-|tetratricopeptide-repeat-protein
MSKTHAKSSEKLTFLTTLNTKNNQTISSSKGIFSIFSAFPEYDRGNRLYEMGRYESAIPYYENAVKIKPDWAIGWLKLAEALSKLQKYEQAVEAYKRSLSLKQNAHQAWHSYGVVLSNLKQYEQAIACFDKAIKINPNDYQSWFNKAIILSELKQDLPAIYCYKEALKIQPMKGEIWYGQGQALLNVQKYAEALAAYDCAAKLQPDNYDIWFKRGLALFQTQRYAEAVISYGHAIELQPENYLGWFNLGIAQSKLHKYHDAVSSFNKAIKLNPDDYEAWYYKGLALKNHWKEGGVACLDKAINFNPNLPEIWISRGYILLDLFKYREALESFNKAITINSNYPESWLGRGKAWMALGKYNEALIAYGNAVSIEPYFLEAWNCRGEALERVQNYDQALAAYDKVIKMSFEQGVSVAKVGLQRGAALEKLERYPEAIEAYNLVIEKQPNNFDGWLNRGLNLEKMANYEEAVLSYSRAISIWPSNYQAWLQLALMLEKLERLDEAIVAYNKIISLRPGNHETWLKRGLILERLGYVQEAVSSYKIVLEIKPDYHEAIERKKRLELTV
>NC_008312.1|WP_011611582.1|3031976_3033209_-|RNA-polymerase-sigma-factor-SigC
MITTSEIYPYTEDTLQSNNLQNECSEHLGQTINELTIEDKKVDSSQINTNYSGRDSVRSYLQEIGRVDLLQRDQEVSTAQKVQRYVHLLELRNKAAEQEQEIQRYVEMIKIRDRLAARLGHKPSFERWLKAGNLSMAELKEIIAVGKLRWAKLTGLNVKELEQIQTEGIEARHQMISTNLRLVVSIAKKYQNRGVELLDLIQEGTLGLERAVEKFDPQRGYRFSTYAYWWIRQGITRAIATQSRTIRLPIHVSEKLNKIKKVQQKIFQEKGYTAKVEEIARELKITAAQVREVLVKIPHSVSLETKVGRDRDTELGELLETKDASPEEMLIRESLVQALKELLLDLTQRERYVITMRYGLEDGRACSLSEIASALKLSRERVRQIEVKALHKLRQPKFRNQIQDYLESLN
>NC_008312.1|WP_011611583.1|3033920_3034799_-|lipoyl-synthase
MVVKPDWLRVKAPQWQRVGTVKEILRDLSLKTVCEEASCPNIGECFNAGTATFLIMGPACTRACPYCDINFEKKPQPLDVNEPKQLAEAVKRLRLNHVVITSVNRDDLTDGGATQFAKCISQVRAISPQTTIEVLIPDLCGNWQALEIILNAKPEVINHNTETVQRLYRRVRPQGNYHRTLELLKRARELAPEIYTKSGIMVGVGETDAEVQEVMKDLRVVDCDILTIGQYLQPSLKHLPVDTFIKPEQFDQWKKIGLSMGFLQVVASPLTRSSYHAEEVKELMVNYPKTKS
>NC_008312.1|WP_011611584.1|3035690_3036203_+|transcriptional-repressor
MALYTPSSFKAELNEKGWRMTPQRETILHIFQNLPKGNHLSAEDLYNMLKNRGERISLSTIYRTLKLMARMGILRELELAEGHKHYEINQPYPHHHHHLVCVQCNKTIEFKNDSILKIGLKQAEKSGLHLLDCQLTIHTICYEALRKGWPSLVSSDCYCPRALADKENCE
>NC_008312.1|WP_011611585.1|3036359_3037823_-|peptidoglycan-binding-protein
MESLAYIELFLVNKEIKDLKFIEKLNWKKLLNLTYINFLSAVIVNSILINDSLAQVSDISIPKTNSYSDFNISRTQNNKTAQEQVAPNSFVSSSRLDNNAVIPTPNSQVYLRCGDFSEIVAEVQRELRELGYFTANLTGYYGQETEIAVKQFQQEKGLKPTGEIEPTTWLLLFPDRKNSQTNSRFFNSSTKVLSFGEVNPQVAIIQRQLAELGFYKGQINSIYDQKTRTAVIQFQNVYGITPTGQVGYTTREFLFETRTIPVERVLRLGNTGLDVRRLQQRLRSLGYYQRQITNYFDLSTETAVIDFQKRNRITPTGIVGQTTKAFLFDADQVLPPGPVSYSRGNYARKHYSYQGLLKPGNEGWAVEQLQILLTRLGYYSGVIDGFFGLRTEFAVRSFQQDLGLVDTGVATIDTLQALRHPLIINQNISEEQFSDIGNQTQVLELQNRLRLQGLYTGPLNGVYNSQTRSAVAEAQLIYGVSGKDIVD
>NC_008312.1|WP_081432424.1|3039942_3040101_-|hypothetical-protein
MTFRLTDLIKVDHIKTRFKGVDNTIKNKQFLHRYCHYTKTPFDYKRYPKPTL
>NC_008312.1|WP_011611587.1|3040868_3041552_-|tRNA-(guanosine(37)-N1)-methyltransferase-TrmD
MRFDVITLFPDFFTTPLNSGLLGRAFNKNIAKVNLVNPRNYTTDKYKKVDDESYGGGVGMVLKPEPIFAAVESLPTLSKREVILLTPQGKRMHQGLFRELATDYEQLILICGHYEGIDERVQYLVSREVSLGDFVLTGGEIPALALINGVVRLLPGTVGKAESLECESFESGLLDYPQYTRPANFRGWKVPEVLLSGHHAEIARWRYQQQLQRTKSRRPDLLKNDDN
>NC_008312.1|WP_011611589.1|3042693_3043569_+|cyanophycinase
MQLESQSLELDTLRPTKTTIMVIGGAEDKVHGKEILQTFFNRSGGVNAKLAVIPSASREPGSQGDRYRKVFKDMGTLNDNIRIFDIRERYQGEDPIWLKYLEDCTGVFMTGGDQLRLCSLLAETPLMDNIRSKALEGKIALAGTSAGAAVMGYHMIAGGGSGSSPNRSLVDITKGLAILPDLIVDQHFHNRNRMARLLSAIATHSDKVGIGIDEDTCALFERDSMIQVMGKGTVTIIDPVEMSYTNSAKVGVEDPLSLSNLRVHILCHGDGYDLHSHTMKPGLSETIMPLD
>NC_008312.1|WP_011611590.1|3043879_3046588_+|cyanophycin-synthetase
MKILKLQTLRGPNYWSIHRHKLVVMRLDLEDLYEKYTSDIPGFYKGLTEVLPSLVEHLCSPGVKGGFLTRVEKGTLIGHVIEHVAIELQELAGMPVGFGRTRETSTTGVFQVVIEYENEQAGRYAARAAVRLCQSIVDTGTYPATELQQDLEDLKELKNQASLGPSTEAIVKEAEARGIPWTQLGARFMIQFGYGVNQKKIQATLSNQTGILGVELACDKEGTKRILKDAGVPVPRGTVARYFDELQDAIEYVGGYPIVIKPLDGNHGRGITIDVKNWQEAEEAYDLARKASKTKTVIVERYYTGKDHRVLVVNGKVVAVAERVPAHVVGNGKSTIAELIEETNRDPQRGDGHDNILTRITVDKSALDILGKQGYSIDSIPLKGKKCFLRATANLSTGGIAVDRTDEIHPENVWLLSRVAKIIGLDIAGIDVVTEDISQPLREVEGVIVEVNAAPGFRMHVAPSRGLARNVAGAVMDMLFPGSKNGRIPILSVTGTNGKTTTTRLLAHIIKQTGKVVGYTTTDGTYIGEYLAETGDNTGPQSAHLILSDPTVEVAVLETARGGILRSGLGFSSCEVGIVLNVTADHLGIGDIDTIEQLAKLKSVVAESVMPKGYAVLNAEDPLVAAMADRVKGQVAYFSMDPNNELLLRHTEAGGLAAIYENGYISILKGDWTLRIEKAVNVPITMAGKAPFMIANALAACLAVFTQGVKIEHIRKGLSTFVASVDQTPGRMNMFNMGSYHALVDYAHNPASYEALGGFVRNWPGKRIGVVGGPGDRRDEDFVSLGELAADIFDEIIIKEDDDTRGRPRGNAAELICQGVKQFLNGIKNSESKATYESILDETAAINTALDRAPIDGLVVILPESVNRAISLIEGRHVIQDIELLQDSQREPKDQEVLKSSI
>NC_008312.1|WP_011611591.1|3047083_3047227_-|high-light-inducible-protein
MDNQEKKLGFTEFAETWNGRLAMLGFIIGIATELLTGQGILSQIGLM
>NC_008312.1|WP_011611592.1|3048339_3050928_+|DUF4912-domain-containing-protein
MKMYFFRKKSVQLLVVLLTLIATPRQLTANNLSFLSNTILNQSINSDTTYSAPKSLPSGRKIKLFSSSSMIVINQVLKQVYEEKYPDAQVEITRGDTSELLEVLLKGETDLVALGRRLTAEEKNQGLVEVPINRGKIAIVVASDNPFQENLSFEKFAQIFRGEITNWSKLGGPQLPIRLIDRPESSDTREALKSYDVFKKSPFMTGRNAIQLSEDDTAVVIKELGKNGISYAIMDQVLNRENVRIIPMHKTLPTNPLYPYSQPRNFVYKNDTASPEVLAFLGLVTSEDGQQVVAKADKQGRSDLANLSSTNKANSSDIVTSPSLDTQIKTELNKQEKTDSETFGGLVTALIGDIGKETGTKRIPWWILLLLNIPILGALLWVFLRRRGNQSVGTGGTRVVPGTTTDSDFTSVGETLFAEAEVTEANDLTETSSENGNEVAVVDPSISVAGVEGVGELLATWASLEKNSQISLSPGESQTVLASWSVPEADQLAAKLHGAKQYQLRVYDVTDIDLDLELAESIKYYNFEDSNQQWQIGSLLFDREYQAEIGYATDDDRWLLLARSNRVRIDISKNADLGRAGQGFDNLLLRDITVEDYVNKDIEVVKEPDLERGERVRGVLLPCKITITPDDAENMMVTWKVSQTAQNALKEQGGKEYQLRIYDVTDIDLDKQPAYNVQGYNCQESIQEMQVPVLMINREYQAEIGYVTDYGKLLKLARSNRIRIPAIEIDDVKTTQLNVTQTKAVIQEEALKSSWVIIVPVSSQSAYVHWGVSQTAKNLAKQQGGQQYQLRIFDITDIDIDSQNAQNVQQYDCDGSSQKQEIPINVSSVGYVDYFAEIGYVTDDSQWLIIARSNPLRIPVLI

Crispr_ID: NC_008312_26

• CRISPR_ID: NC_008312_26
• CRISPR_location: 3607264-3607379
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NC_008312_26

Consensus_repeat	Method
CAATATATAGTTTAAGTAAGAATAATCAGGCTAATAAAG	CRISPRCasFinder

spacers of NC_008312_26

>26.1|3607303|38|NC_008312|CRISPRCasFinder
TAAGTTTATTGTCATAGTGTGTAATTTAAGTTAGCAGC

CRISPR arrays and Neighbor proteins around NC_008312_26

CRISPR arrays

The CRISPR arrays of NC_008312_26

>merge|NC_008312|26|3607264-3607379|CRISPRCasFinder
CAATATATAGTTTAAGTAAGAATAATCAGGCTAATAAAGTAAGTTTATTGTCATAGTGTGTAATTTAAGTTAGCAGCCAATATATAGTTTAAGTAAGAATAACCAGGCTAATAAAG

>NC_008312|26|21|3607264-3607379|CRISPRCasFinder
CAATATATAGTTTAAGTAAGAATAATCAGGCTAATAAAG	TAAGTTTATTGTCATAGTGTGTAATTTAAGTTAGCAGC
CAATATATAGTTTAAGTAAGAATAACCAGGCTAATAAAG

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_008312.1|WP_011611926.1|3614310_3615111_+|GvpL/GvpF-family-gas-vesicle-protein	unknown	unknown	gnl|CDD|377652
NC_008312.1|WP_011611915.1|3600514_3601087_+|hypothetical-protein	unknown	unknown	gnl|CDD|380155
NC_008312.1|WP_011611927.1|3615411_3616089_+|hypothetical-protein	unknown	unknown	gnl|CDD|377652
NC_008312.1|WP_011611930.1|3618886_3619681_-|hypothetical-protein	unknown	unknown	unknown
NC_008312.1|WP_011611924.1|3610553_3612473_-|AAA-family-ATPase	unknown	unknown	gnl|CDD|273521
NC_008312.1|WP_011611914.1|3599248_3599467_+|gas-vesicle-structural-protein-GvpA	unknown	unknown	gnl|CDD|181805
NC_008312.1|WP_011611920.1|3605595_3605820_+|hypothetical-protein	unknown	unknown	unknown
NC_008312.1|WP_011611912.1|3597654_3597819_+|gas-vesicle-synthesis-protein-GvpA	unknown	unknown	gnl|CDD|236485
NC_008312.1|WP_011611918.1|3604201_3605137_+|gas-vesicle-protein-GvpN	unknown	unknown	gnl|CDD|131688
NC_008312.1|WP_011611913.1|3598478_3598706_+|gas-vesicle-structural-protein-GvpA	unknown	unknown	gnl|CDD|181805
NC_008312.1|WP_011611917.1|3603599_3604016_+|hypothetical-protein	unknown	unknown	gnl|CDD|368550
NC_008312.1|WP_011611921.1|3606013_3606475_+|gas-vesicle-protein-K	unknown	unknown	gnl|CDD|377462
NC_008312.1|WP_011611919.1|3605133_3605445_+|gas-vesicle-protein	unknown	unknown	gnl|CDD|376379
NC_008312.1|WP_011611929.1|3617963_3618434_-|SsrA-binding-protein-SmpB	unknown	unknown	gnl|CDD|235455
NC_008312.1|WP_011611925.1|3613721_3613979_-|gas-vesicle-protein-GvpG	unknown	unknown	gnl|CDD|310007
NC_008312.1|WP_071820682.1|3601649_3603533_+|ArsA-family-ATPase	unknown	unknown	gnl|CDD|349755
NC_008312.1|WP_011611931.1|3619957_3620287_-|DUF3082-domain-containing-protein	unknown	unknown	gnl|CDD|371449
NC_008312.1|WP_011611923.1|3609063_3609378_+|gas-vesicle-protein	unknown	unknown	gnl|CDD|376379
NC_008312.1|WP_011611922.1|3608131_3609067_+|gas-vesicle-protein-GvpN	unknown	unknown	gnl|CDD|131688
NC_008312.1|WP_044136726.1|3609392_3609575_+|hypothetical-protein	unknown	unknown	unknown

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_008312.1|WP_011611926.1|3614310_3615111_+|GvpL/GvpF-family-gas-vesicle-protein	gnl|CDD|377652	pfam06386, GvpL_GvpF, Gas vesicle synthesis protein GvpL/GvpF. This family consists of several bacterial and archaeal gas vesicle synthesis protein (GvpL/GvpF) sequences. The exact function of this family is unknown.	2.82422e-71
NC_008312.1|WP_011611915.1|3600514_3601087_+|hypothetical-protein	gnl|CDD|380155	NF012221, MARTX_Nterm, MARTX multifunctional-autoprocessing repeats-in-toxin holotoxin RtxA. This model describes the N-terminal 1900 amino acids of MARTX family multifunctional-autoprocessing repeats-in-toxin holotoxins, which contain both repeat regions that facilitate their entry into eukaryotic target cells, and multiple effector domains.	0.00246624
NC_008312.1|WP_011611927.1|3615411_3616089_+|hypothetical-protein	gnl|CDD|377652	pfam06386, GvpL_GvpF, Gas vesicle synthesis protein GvpL/GvpF. This family consists of several bacterial and archaeal gas vesicle synthesis protein (GvpL/GvpF) sequences. The exact function of this family is unknown.	1.91215e-18
NC_008312.1|WP_011611924.1|3610553_3612473_-|AAA-family-ATPase	gnl|CDD|273521	TIGR01243, Cell_division_cycle_protein_48_homolog_MJ1156, AAA family ATPase, CDC48 subfamily. This subfamily of the AAA family ATPases includes two members each from three archaeal species. It also includes yeast CDC48 (cell division control protein 48) and the human ortholog, transitional endoplasmic reticulum ATPase (valosin-containing protein). These proteins in eukaryotes are involved in the budding and transfer of membrane from the transitional endoplasmic reticulum to the Golgi apparatus.	0
NC_008312.1|WP_011611914.1|3599248_3599467_+|gas-vesicle-structural-protein-GvpA	gnl|CDD|181805	PRK09371, PRK09371, gas vesicle structural protein GvpA.	8.85822e-28
NC_008312.1|WP_011611912.1|3597654_3597819_+|gas-vesicle-synthesis-protein-GvpA	gnl|CDD|236485	PRK09368, PRK09368, gas vesicle structural protein GvpA.	2.0083e-17
NC_008312.1|WP_011611918.1|3604201_3605137_+|gas-vesicle-protein-GvpN	gnl|CDD|131688	TIGR02640, Gas_vesicle_protein_GvpN, gas vesicle protein GvpN. Members of this family are the GvpN protein associated with the production of gas vesicles produced in some prokaryotes to give cells buoyancy. This family belongs to a larger family of ATPases (pfam07728). [Cellular processes, Other].	1.10537e-127
NC_008312.1|WP_011611913.1|3598478_3598706_+|gas-vesicle-structural-protein-GvpA	gnl|CDD|181805	PRK09371, PRK09371, gas vesicle structural protein GvpA.	3.73468e-27
NC_008312.1|WP_011611917.1|3603599_3604016_+|hypothetical-protein	gnl|CDD|368550	pfam05667, DUF812, Protein of unknown function (DUF812). This family consists of several eukaryotic proteins of unknown function.	0.00451602
NC_008312.1|WP_011611921.1|3606013_3606475_+|gas-vesicle-protein-K	gnl|CDD|377462	pfam05121, GvpK, Gas vesicle protein K. These proteins are involved in the formation of gas vesicles.	7.86427e-30
NC_008312.1|WP_011611919.1|3605133_3605445_+|gas-vesicle-protein	gnl|CDD|376379	pfam00741, Gas_vesicle, Gas vesicle protein.	5.13759e-13
NC_008312.1|WP_011611929.1|3617963_3618434_-|SsrA-binding-protein-SmpB	gnl|CDD|235455	PRK05422, smpB, SsrA-binding protein SmpB.	1.71035e-91
NC_008312.1|WP_011611925.1|3613721_3613979_-|gas-vesicle-protein-GvpG	gnl|CDD|310007	pfam05120, GvpG, Gas vesicle protein G. These proteins are involved in the formation of gas vesicles.	2.04918e-12
NC_008312.1|WP_071820682.1|3601649_3603533_+|ArsA-family-ATPase	gnl|CDD|349755	cd02035, ArsA, Arsenical pump-driving ATPase ArsA. ArsA ATPase functions as an efflux pump located on the inner membrane of the cell. This ATP-driven oxyanion pump catalyzes the extrusion of arsenite, antimonite and arsenate. Maintenance of a low intracellular concentration of oxyanion produces resistance to the toxic agents. The pump is composed of two subunits, the catalytic ArsA subunit and the membrane subunit ArsB, which are encoded by arsA and arsB genes, respectively. Arsenic efflux in bacteria is catalyzed by either ArsB alone or by ArsAB complex. The ATP-coupled pump, however, is more efficient. ArsA is composed of two homologous halves, A1 and A2, connected by a short linker sequence.	4.60985e-56
NC_008312.1|WP_011611931.1|3619957_3620287_-|DUF3082-domain-containing-protein	gnl|CDD|371449	pfam11282, DUF3082, Protein of unknown function (DUF3082). This family of proteins has no known function.	1.6981e-28
NC_008312.1|WP_011611923.1|3609063_3609378_+|gas-vesicle-protein	gnl|CDD|376379	pfam00741, Gas_vesicle, Gas vesicle protein.	5.73176e-13
NC_008312.1|WP_011611922.1|3608131_3609067_+|gas-vesicle-protein-GvpN	gnl|CDD|131688	TIGR02640, Gas_vesicle_protein_GvpN, gas vesicle protein GvpN. Members of this family are the GvpN protein associated with the production of gas vesicles produced in some prokaryotes to give cells buoyancy. This family belongs to a larger family of ATPases (pfam07728). [Cellular processes, Other].	7.26805e-126

Protein sequences

>NC_008312.1|WP_011611921.1|3606013_3606475_+|gas-vesicle-protein-K
MSLENSPEESLIVPIDKSKSNPEAGLAPLLLTVIELLRELMQAQVIRRMDAGILSDEQLERAAEGLRQLEEQVIKLCKVFDIPTEDLNLDLGEIGTLLPKSGEYYPGEKSENPSVLELLDRILNTGVVLDGTVDLGLAELDLIHARLRLVLTA
>NC_008312.1|WP_011611920.1|3605595_3605820_+|hypothetical-protein
MVTNTAKKIKTSLKNIKTQGDIKTPGDIKALENILSSSAVRGCLSCESIKGDKTRVLETARILVAQNRVLSQQK
>NC_008312.1|WP_011611919.1|3605133_3605445_+|gas-vesicle-protein
MKTSANIATSASGNGLADVLERVLDKGVVIAGDISVSIASTELLNIKIRLLISSVERAKEIGINWWESDPYFSSQNNSLVQANEKLLERVASLESEIKALRSN
>NC_008312.1|WP_011611918.1|3604201_3605137_+|gas-vesicle-protein-GvpN
MTTVLNVSPDRFVSTPGVERVTQRASRYLESGYSVHLRGPAGVGKTTLALHLAHLRQQPIFLMIGDDEFKTSDLIGNKSGYTRKKLVDNYIHTVLKVEDELRDNWIDSRLTLACKEGFTLIYDEFNRSRPEVNNVLLSVLEEKMLVLPPSQNQSEYIQVHPQFRVILTSNSEEWTGVHATQDALLDRVVTIGMEQPDISTEQNIVIQKTGINPLKAEVIIKLVRSVRQRVDKEDLGSLRSALMISKVCHDHDIPLDGKDSSFSDLCADILISRPNLPRQEALQQLDEVLEEFFPADQPSSSDVGLEKEGSL
>NC_008312.1|WP_011611917.1|3603599_3604016_+|hypothetical-protein
MFTSQQVYLLAMNNSARRISFSKNQSIVPRKKYDSSTYLNIYQSVVRKEHLSREMNRIQERCDQIKEEIAFLDKKIKNEKMTLKDQKVEEINEEKESKSSEINEEKKSKPSYQPKINELKNQTSMPVQSKFKTINFGY
>NC_008312.1|WP_071820682.1|3601649_3603533_+|ArsA-family-ATPase
MMYSFDNLNLVMFSGKGGVGKTTNSCAFAGHWAKKSPNEKVLLISTDPAHSLGDVLQISVTDTPRPLEDLPNLLVRALDVNLLLEEFKKRYGDVLEVIVERGSFVEGGDLTPVWDLDWPGLDELMALLEIQRLCNEKVVDRVVVDMAPSGHTLNLFKLMDFLDTFLNSLELFQEKHKYIKKSFSGSYIPNEVDEVLQNLKDELAAGRHLLQNSSNTACLVVALPEPMSFRETQRFLSSLEEIKIPYAGIVVNQIVVDKDGNSDRYHEQQKLVNDFIKLAGDKPVFLVPQEKAEPLGVTALEKLTNQINQATIQEFSTSISFNIQWPEKVPPGFTDFIGKGKRLLIVGGKGGVGKTTIAAAISWEMAKRYPERQVRAVSIDPAHSLGDAFGMDLCHEPSIISSNLKGQEIEANKVLEKFREDYLWELAEMMSGEKSENQASFEMAFAPKGWRQIVEQALPGIDEILSFITVIELLEEKQEDLIVLDTAPTGHLLRFLEMPTAIQDWLGWIFKLWIKYQDIIGKTDFMGRLRTLRQRVVKAQKILKDPKKTEFIGVIRPQKGVIAEAERLYKSLAEMHIPQNYLVLNCFTSNSVIPTDQFPGVQFVCMPMLPRSIEPIEQIKGAATYIF
>NC_008312.1|WP_011611915.1|3600514_3601087_+|hypothetical-protein
MALIDIWEKSTEIRKDEVLQIHETGKEEKKQRQDVIVQRQNEVQVIHNEALEEKNQRQDVIVKRQNEVQVIHNEALEEKKQRQDVIVERQNDTKADHEKAVADKSQRQDVIVQRQNDTKADHEKAVADKSQRQDVIVERQNDTKADHEKALADKKQRQDEKDERRSYVWGYKAGIETKQTSSNDSYQQIA
>NC_008312.1|WP_011611914.1|3599248_3599467_+|gas-vesicle-structural-protein-GvpA
MAVEKVNSSSSLAEVIDRILDKGVVVDAWVRLSLVGIELLTIEARIVIASVETYLKYAEAVGLTTLAAEPAA
>NC_008312.1|WP_011611913.1|3598478_3598706_+|gas-vesicle-structural-protein-GvpA
MAVEKVNSSSSLAEVIDRILDKGVVVDAWIRLSLVGIELLTIEARIVVASVETYLKYAEAVGLTTLAAAPGEAAA
>NC_008312.1|WP_011611912.1|3597654_3597819_+|gas-vesicle-synthesis-protein-GvpA
MFIRVDFLLDKGVIVDAWVRLSLVVIELLTIEAKIVIASVEAYLKYSEAFCFNY
>NC_008312.1|WP_011611922.1|3608131_3609067_+|gas-vesicle-protein-GvpN
MTTVLNVSPDRFVSTPSVERVTQRASRYLESGYSVHLRGPAGVGKTTLALHLAHLRQQPIFLMIGDDEFKTSDLIGNKSGYTRKKLVDNYIHTVLKVEDELKHNWIDSRLTLACKEGFTLIYDEFNRSRPEVNNVLLSVLEEKMLVLPPSQNQSEYIQVHPQFRVILTSNSEEWTGVHATQDALLDRVVTIGMGQPDISTEQNIIIQKTGINPLKAEVIIKLVRSVRERLETEDLGSLRSALMISKVCHDHDIPLGGKDSNFSDLCADILISRANLPRQEALKQLDEVLEELFPADQLSISDIGLKKEGSL
>NC_008312.1|WP_011611923.1|3609063_3609378_+|gas-vesicle-protein
MKTSANIAKSAGGDSLADVLERVLDKGIVIAGDISVSIASTELLNIKIRLLISSVERAKEIGINWWESDPSLSSQNNSLVQVNQKLLERVASLESEIEALKYSQ
>NC_008312.1|WP_044136726.1|3609392_3609575_+|hypothetical-protein
MKINKVKNNQLKRIKTRQNILNSTGLRGCSSCNSITGQNNREVEKTRILIARAKVSSQKR
>NC_008312.1|WP_011611924.1|3610553_3612473_-|AAA-family-ATPase
MNNFFGLDVKDLVELAKTLEEKAKSGEIKTSFEVQSGPMRNIPRHGNIPRGMGRSNYQAQTGQSSQDTNFTVQSPNKDSVTQNRAQEKTNSTTSSPETKLRPTLRDIGGMSEVIQELREVIELPLKRPDLLTKLGLEPSRGVLLVGPPGTGKTLTAKAIAEELGLNYIAINGPEVMSKYYGEAEGKLRDIFAKAKKSAPCLIFIDEIDSIAPDRSKVEGEVEKRLVAQLLGLMDGFEVLEGVLLLAATNRPDHIDPALRRPGRFDQEVYFHVPDRDGRSEILQILTKAMPLDNSVDLEEIADLAVGLVGADLKAVCQKAAYFALRREVPSLENLNIQTPEDMSLLQSDLLRAIKEIKPSILRSVAVEVPNVSWQHIGGLDVVKQKLQESVEGALLYPELYEKTKAKAPKGILLWGEPGTGKTLLAKAVASQAQANFIAVNGPELLSKWVGAAEEAVRELFSKARQVSPCVIFIDEIDTLAPARGKTMGDSGVSDRLVGQLLTELDGLRDCTQLLLVGATNRPDALDPALLRAGRLDLQIKVDLPDQASRLEILKVHNQDRPLEEVNLEDWASRTEGWNGADLALLTNQAALAAIRSYSAQGIKSSKENDIKITSADFENAYNALKSQKQSNNFDSDICV
>NC_008312.1|WP_011611925.1|3613721_3613979_-|gas-vesicle-protein-GvpG
MLLRLLTLPISGPLEGVTWLGKKLQEQVDTEIDETENLSKKLLTLQLAFDMGEISEEDFEDQEEELLLAIQALEEQKLKEEEEDA
>NC_008312.1|WP_011611926.1|3614310_3615111_+|GvpL/GvpF-family-gas-vesicle-protein
MEFGFYVYGLIQEKGKMDESKDESKNGLKGSNESKDELKGLDKEDVKIQDVDEFAVLYSIAKKERYLASRRNLITHEKVLESAMEAGYRNLLPMQFGLVVSEWEKFSQDFTKPCEQQIHDLFTKLKNNREVGIKIYWEPDAELEKLLENDKDLKEERDSLKDKKLTMDQVIDIGQKIEQGMNERKQNIIEIFQETLNKMAIEVIENEVQTEKMIYNAAYLIPWDQEEDFGEKVETIDSKLCERGNFTIRYNSFTAPYNFARIRQQD
>NC_008312.1|WP_011611927.1|3615411_3616089_+|hypothetical-protein
MSYYVYGFLYLPESCLALPKGMEKEVELVPYQNIAAVVEANVSIEAIQETEEKLLEAILAHDRVVREIFQQVSMLPLRFGNAFALRENIINDLQNNQQQYLNILTKLQQQAEYTITFTPVSYPSTLEVSKVRGKAYLLAKKQQFEQQQAFQTKQRQQWENIRQLIFKNYPKAVFRDSTESKIKQVHLLANRDARVITTEELSTWQTECSYWQITLSEQLPPYHFV
>NC_008312.1|WP_011611929.1|3617963_3618434_-|SsrA-binding-protein-SmpB
MAKKSGEGQKIISDNRQARFNYHIIETYEAGVALQGTEVKSIREGKVNLRDGYALIRNNEAWLLNVHISPYQKAGDFFNHEPRRSRRLLLHKQEIRKLIGKVEQQGLTLVPLRMYFKRGWVKVDIALAQGKKLYDKRETIKRRDDKRAMQRAIKQY
>NC_008312.1|WP_011611930.1|3618886_3619681_-|hypothetical-protein
MSEDQPKQINSEQPQTEAISQETTENPSMISETQPPEQPISDNESVVAKPRLWQQVLGLVRSLLPQSLNKNLSDNFLSVAVTGIFALILVVIFVSISPSQDIPVVAEYELNEETPAPESLSSTIDSKNPQLSETALQEALESTEPIITPPPELTPEQTFLVSIQNQIDDLANQYAGGIIKSLKFYLSTNLLMAELSNDWYNMTQEEQNKLVNQMFEEVQDLDFKKLILINSQGRTIARTSVINSYMIILERSLLKLPESFDSKE
>NC_008312.1|WP_011611931.1|3619957_3620287_-|DUF3082-domain-containing-protein
MTNSTPKSNKKSTPKVNPLQCLASAVISGSLATVTYSLMQSVAKTFASKPITSDNFLVVNLSGAVRTLVVGVIALVACICAIVTLGLIALAIQTIIHRFTNKEMPPNEG

Crispr_ID: NC_008312_27

• CRISPR_ID: NC_008312_27
• CRISPR_location: 3627622-3627843
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NC_008312_27

Consensus_repeat	Method
GCAGGTGGTAGGGTTGAATTTCTACTAAGGTTCATTGGTGCTTTTATTTATTTA	CRISPRCasFinder

spacers of NC_008312_27

>27.1|3627676|114|NC_008312|CRISPRCasFinder
ATGTAGGCGGCAGGTCTCAGGTTTCAGGCCGCAGGTGGTAGGGTTGAATTTCTACTAAGGTTCATTGGTGCTTTTATTTATTTAATGTAGGCGGCAGGTCTCAGGTTTCAGGCG

CRISPR arrays and Neighbor proteins around NC_008312_27

CRISPR arrays

The CRISPR arrays of NC_008312_27

>merge|NC_008312|27|3627622-3627843|CRISPRCasFinder
GCAGGTGGTAGGGTTGAATTTCTACTAAGGTTCATTGGTGCTTTTATTTATTTAATGTAGGCGGCAGGTCTCAGGTTTCAGGCCGCAGGTGGTAGGGTTGAATTTCTACTAAGGTTCATTGGTGCTTTTATTTATTTAATGTAGGCGGCAGGTCTCAGGTTTCAGGCGGCAGGTGGTAGGGTTGAATTTCTACTAAGGTTCATTGGTGCTTTTATTTATTTA

>NC_008312|27|22|3627622-3627843|CRISPRCasFinder
GCAGGTGGTAGGGTTGAATTTCTACTAAGGTTCATTGGTGCTTTTATTTATTTA	ATGTAGGCGGCAGGTCTCAGGTTTCAGGCCGCAGGTGGTAGGGTTGAATTTCTACTAAGGTTCATTGGTGCTTTTATTTATTTAATGTAGGCGGCAGGTCTCAGGTTTCAGGCG
GCAGGTGGTAGGGTTGAATTTCTACTAAGGTTCATTGGTGCTTTTATTTATTTA

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_008312.1|WP_011611939.1|3633779_3635186_-|magnesium-transporter	unknown	unknown	gnl|CDD|129495
NC_008312.1|WP_011611926.1|3614310_3615111_+|GvpL/GvpF-family-gas-vesicle-protein	unknown	unknown	gnl|CDD|377652
NC_008312.1|WP_011611938.1|3632058_3632676_-|hypothetical-protein	unknown	unknown	gnl|CDD|237177
NC_008312.1|WP_011611943.1|3643249_3643588_-|hypothetical-protein	unknown	unknown	gnl|CDD|375906
NC_008312.1|WP_011611934.1|3624339_3625269_+|signal-transduction-histidine-kinase	unknown	unknown	gnl|CDD|223716
NC_008312.1|WP_011611936.1|3628412_3630362_-|serine-protease	unknown	unknown	gnl|CDD|276809
NC_008312.1|WP_011611937.1|3631291_3631852_-|hypothetical-protein	unknown	unknown	gnl|CDD|372967
NC_008312.1|WP_011611930.1|3618886_3619681_-|hypothetical-protein	unknown	unknown	unknown
NC_008312.1|WP_011611932.1|3620966_3622208_-|glycoside-hydrolase	unknown	unknown	gnl|CDD|212110
NC_008312.1|WP_011611941.1|3638103_3639891_+|aspartate--tRNA-ligase	unknown	unknown	gnl|CDD|234775
NC_008312.1|WP_011611944.1|3643589_3643964_-|DUF433-domain-containing-protein	unknown	unknown	gnl|CDD|225291
NC_008312.1|WP_011611927.1|3615411_3616089_+|hypothetical-protein	unknown	unknown	gnl|CDD|377652
NC_008312.1|WP_011611931.1|3619957_3620287_-|DUF3082-domain-containing-protein	unknown	unknown	gnl|CDD|371449
NC_008312.1|WP_011611933.1|3622432_3622984_-|hypothetical-protein	unknown	unknown	unknown
NC_008312.1|WP_011611925.1|3613721_3613979_-|gas-vesicle-protein-GvpG	unknown	unknown	gnl|CDD|310007
NC_008312.1|WP_011611942.1|3640630_3642940_-|TOMM-precursor-leader-peptide-binding-protein	unknown	unknown	gnl|CDD|376866
NC_008312.1|WP_011611935.1|3626090_3627389_-|serine/threonine-protein-kinase	unknown	unknown	gnl|CDD|270916
NC_008312.1|WP_155994394.1|3644125_3644323_+|hypothetical-protein	unknown	unknown	gnl|CDD|341357
NC_008312.1|WP_011611929.1|3617963_3618434_-|SsrA-binding-protein-SmpB	unknown	unknown	gnl|CDD|235455
NC_008312.1|WP_011611940.1|3635608_3637234_-|sodium:proton-antiporter	unknown	unknown	gnl|CDD|223104

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_008312.1|WP_011611939.1|3633779_3635186_-|magnesium-transporter	gnl|CDD|129495	TIGR00400, mgtE, Mg2+ transporter (mgtE). This family of prokaryotic proteins models a class of Mg++ transporter first described in Bacillus firmus. May form a homodimer. [Transport and binding proteins, Cations and iron carrying compounds].	4.43161e-168
NC_008312.1|WP_011611925.1|3613721_3613979_-|gas-vesicle-protein-GvpG	gnl|CDD|310007	pfam05120, GvpG, Gas vesicle protein G. These proteins are involved in the formation of gas vesicles.	2.04918e-12
NC_008312.1|WP_011611926.1|3614310_3615111_+|GvpL/GvpF-family-gas-vesicle-protein	gnl|CDD|377652	pfam06386, GvpL_GvpF, Gas vesicle synthesis protein GvpL/GvpF. This family consists of several bacterial and archaeal gas vesicle synthesis protein (GvpL/GvpF) sequences. The exact function of this family is unknown.	2.82422e-71
NC_008312.1|WP_011611940.1|3635608_3637234_-|sodium:proton-antiporter	gnl|CDD|223104	COG0025, NhaP, NhaP-type Na+/H+ and K+/H+ antiporters [Inorganic ion transport and metabolism].	2.02898e-42
NC_008312.1|WP_011611943.1|3643249_3643588_-|hypothetical-protein	gnl|CDD|375906	pfam18480, DUF5615, Domain of unknown function (DUF5615). This is a domain of unknown function found in potential toxin-antitoxin system component.	1.04212e-21
NC_008312.1|WP_011611934.1|3624339_3625269_+|signal-transduction-histidine-kinase	gnl|CDD|223716	COG0643, CheA, Chemotaxis protein histidine kinase and related kinases [Cell motility and secretion / Signal transduction mechanisms].	4.24132e-27
NC_008312.1|WP_011611936.1|3628412_3630362_-|serine-protease	gnl|CDD|276809	sd00006, TPR, Tetratricopeptide repeat. The Tetratricopeptide repeat (TPR) typically contains 34 amino acids and is found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi, plants, and humans. It is present in a variety of proteins including those involved in chaperone, cell-cycle, transcription, and protein transport complexes. The number of TPR motifs varies among proteins. Those containing 5-6 tandem repeats generate a right-handed helical structure with an amphipathic channel that is thought to accommodate an alpha-helix of a target protein. It has been proposed that TPR proteins preferentially interact with WD-40 repeat proteins, but in many instances several TPR-proteins seem to aggregate to multi-protein complexes.	1.25308e-28
NC_008312.1|WP_011611937.1|3631291_3631852_-|hypothetical-protein	gnl|CDD|372967	pfam14218, COP23, Circadian oscillating protein COP23. This family includes the circadian oscillating protein COP23 from Cyanothece sp. (strain PCC 8801). The levels of this peripheral membrane protein display a circadian oscillation.	1.39476e-37
NC_008312.1|WP_011611932.1|3620966_3622208_-|glycoside-hydrolase	gnl|CDD|212110	cd10798, GH57N_like_1, Uncharacterized subfamily of glycoside hydrolase family 57 (GH57). This subfamily of uncharacterized bacterial proteins, shows high sequence homology to glycoside hydrolase family 57 (GH57). Glycoside hydrolase family 57(GH57) is a chiefly prokaryotic family with the majority of thermostable enzymes coming from extremophiles (many of these are archaeal hyperthermophiles), which exhibit the enzyme specificities of alpha-amylase (EC 3.2.1.1), 4-alpha-glucanotransferase (EC 2.4.1.25), amylopullulanase (EC 3.2.1.1/41), and alpha-galactosidase (EC 3.2.1.22).	1.5698e-111
NC_008312.1|WP_011611944.1|3643589_3643964_-|DUF433-domain-containing-protein	gnl|CDD|225291	COG2442, COG2442, Uncharacterized conserved protein [Function unknown].	2.88512e-19
NC_008312.1|WP_011611927.1|3615411_3616089_+|hypothetical-protein	gnl|CDD|377652	pfam06386, GvpL_GvpF, Gas vesicle synthesis protein GvpL/GvpF. This family consists of several bacterial and archaeal gas vesicle synthesis protein (GvpL/GvpF) sequences. The exact function of this family is unknown.	1.91215e-18
NC_008312.1|WP_011611931.1|3619957_3620287_-|DUF3082-domain-containing-protein	gnl|CDD|371449	pfam11282, DUF3082, Protein of unknown function (DUF3082). This family of proteins has no known function.	1.6981e-28
NC_008312.1|WP_011611941.1|3638103_3639891_+|aspartate--tRNA-ligase	gnl|CDD|234775	PRK00476, aspS, aspartyl-tRNA synthetase; Validated.	0
NC_008312.1|WP_011611938.1|3632058_3632676_-|hypothetical-protein	gnl|CDD|237177	PRK12704, PRK12704, phosphodiesterase; Provisional.	0.00514768
NC_008312.1|WP_011611942.1|3640630_3642940_-|TOMM-precursor-leader-peptide-binding-protein	gnl|CDD|376866	pfam02624, YcaO, YcaO cyclodehydratase, ATP-ad Mg2+-binding. YcaO is an ATP- an Mg2+-binding protein involved in the peptidic biosynthesis of azoline. There three motifs involved in the binding are, in UniProtKB:P75838, 71-79: Sx3ExxER, 184-203: Sx6Ex3Qx3ExxER, and 286-290: RxxxE. Three slightly different functional families are represented in this family, proteins involved in TOMM (thiazole/oxazole-modified microcin) biogenesis, non-TOMM proteins such as UniProtKB:P75838, and TfuA-associated non-TOMM proteins involved in trifolitoxin biosynthesis. UniProtKB:P75838 hydrolyzes ATP to AMP and pyrophosphate.	9.63006e-116
NC_008312.1|WP_011611935.1|3626090_3627389_-|serine/threonine-protein-kinase	gnl|CDD|270916	cd14014, STKc_PknB_like, Catalytic domain of bacterial Serine/Threonine kinases, PknB and similar proteins. STKs catalyze the transfer of the gamma-phosphoryl group from ATP to serine/threonine residues on protein substrates. This subfamily includes many bacterial eukaryotic-type STKs including Staphylococcus aureus PknB (also called PrkC or Stk1), Bacillus subtilis PrkC, and Mycobacterium tuberculosis Pkn proteins (PknB, PknD, PknE, PknF, PknL, and PknH), among others. S. aureus PknB is the only eukaryotic-type STK present in this species, although many microorganisms encode for several such proteins. It is important for the survival and pathogenesis of S. aureus as it is involved in the regulation of purine and pyrimidine biosynthesis, cell wall metabolism, autolysis, virulence, and antibiotic resistance. M. tuberculosis PknB is essential for growth and it acts on diverse substrates including proteins involved in peptidoglycan synthesis, cell division, transcription, stress responses, and metabolic regulation. B. subtilis PrkC is located at the inner membrane of endospores and functions to trigger spore germination. Bacterial STKs in this subfamily show varied domain architectures. The well-characterized members such as S. aureus and M. tuberculosis PknB, and B. subtilis PrkC, contain an N-terminal cytosolic kinase domain, a transmembrane (TM) segment, and mutliple C-terminal extracellular PASTA domains. The PknB subfamily is part of a larger superfamily that includes the catalytic domains of other protein STKs, protein tyrosine kinases, RIO kinases, aminoglycoside phosphotransferase, choline kinase, and phosphoinositide 3-kinase.	1.18645e-67
NC_008312.1|WP_011611929.1|3617963_3618434_-|SsrA-binding-protein-SmpB	gnl|CDD|235455	PRK05422, smpB, SsrA-binding protein SmpB.	1.71035e-91
NC_008312.1|WP_155994394.1|3644125_3644323_+|hypothetical-protein	gnl|CDD|341357	cd16382, XisI-like, XisI is FdxN element excision controlling factor protein. This family contains XisI proteins, also known as FdxN element excision controlling factors, and similar proteins. FdxN element is excised from the chromosome during heterocyst differentiation in cyanobacteria. This is accomplished by the large serine recombinase XisF (fdxN element site-specific recombinase). The xisH as well as the xisF and xisI genes are required. XisI may function as recombination directionality factor (RDF), and needs XisH which may function as an endonuclease.	2.17131e-24

Protein sequences

>NC_008312.1|WP_011611935.1|3626090_3627389_-|serine/threonine-protein-kinase
MTKNQLLDNRYQIINKLHETNLSITFQGKDTKNFNRLCLIKQLKSSYNPQLKKQLEQRFQQEAKILERLGNHPQIPDLYSYFSENNQFYLIQEWIAGGNLQERLEKQGKLTESEVKDILIKILPVLEFLQKNQIIHRDIKPSNIMVNREKLPILIDFGIVKEIYTIVNQKTPYTVLGIGTPGFISPEQKKGQPTHASDIYSLGLTAIYLLSNQLPIDPFSWRKDVPNINSEFSNILSRAIEENLSDRYNTATEMLTELNKPQSLIPTRVLQNPAPAPSSKMQNSKLLIIQISLTFIAIIVTILSQATNIFINLNKSKELYKKIDIENIEIIAKKSLNLTIKKAKLAINKAKTSQKKAELEIARDELQIAIKELENIPENQSIENQIQTKKTEYLKIINQINQALKKRPCYELLFQIDSCQEYPIKLDLPLSP
>NC_008312.1|WP_011611934.1|3624339_3625269_+|signal-transduction-histidine-kinase
MASEQEERIKQLFITEAEEHLVTLENGLVDLKSTISDVEVINDMFRAAHSVKGGAAMLGIHSVKQIAHRLEDCFKIIRENSINVNQTIESQFLKGYDLLKYLVELMQGPYGLREEEGEKIVQNALPIFAELENNLNILASTETTNQSTTTSNKKEKTSFDQQVKEQLKEMLELFKKADSPSSRKQLIESCNGLLKLDTNTKAWQVLVTTSQKALANSKLSYHVLAPVIIRELNQAGEFIQVGKVKEIVLSKDLKEIAISPKARTCENTKVSLPKEPKEMVKLIINNFDSRQKEAIAKLLIKHIKSSRNR
>NC_008312.1|WP_011611933.1|3622432_3622984_-|hypothetical-protein
MLHSNTIENINPLTDNFSVKNKDKFASTNEYKQIKSDSNVPSYIHLNLDNLKCFEQVDNQFQNWGITFSNAIIIEPSNPAFAVPEGVKVLIGGPKNGRIEMYFRSPAKFVSALTRNSHRTIVSAYNQNEELLAKDEIPTSSLLNSNSMISPKTQLTVNAEKIYKVVFYAFDGQFIIIDLSVGF
>NC_008312.1|WP_011611932.1|3620966_3622208_-|glycoside-hydrolase
MFNNSQVIFVPWLHFHQPPVWNNGKLQGNLEKMLNSEANSEEHWNAQWFAQAYKNPARYAQQLTLEGHQPRMMVDYSGVLLEEMAKLSKNGIFSNIYVDGKCIGDVISLWQEVLTEYSDTIEFTGSAYSHCYFPATPERDHEAQIMQWRKVFADLFGEKALSRVRGFWPPEMGVSGNPAEALRFVRLLKKCGYEWIILPNAALEHPQGWSTPELENRVHWLVVESCGESERILCVVRDTDMGIRQQSGHNAEGCIDDLRYRSRVVGMKPPGLVVPTSDGENGNVMMFEYFKNSFAPLFRERHRWLDVGFMTVSEYIDTYLSPGEITEVRLKSTGGSWIGGHQQWQEGDLRQQVLAAVEQLSQDYAKVVESGKGSVQKSKALLLCETSCFVYWGSDFWAQQAKLFIDRARNILL
>NC_008312.1|WP_011611931.1|3619957_3620287_-|DUF3082-domain-containing-protein
MTNSTPKSNKKSTPKVNPLQCLASAVISGSLATVTYSLMQSVAKTFASKPITSDNFLVVNLSGAVRTLVVGVIALVACICAIVTLGLIALAIQTIIHRFTNKEMPPNEG
>NC_008312.1|WP_011611930.1|3618886_3619681_-|hypothetical-protein
MSEDQPKQINSEQPQTEAISQETTENPSMISETQPPEQPISDNESVVAKPRLWQQVLGLVRSLLPQSLNKNLSDNFLSVAVTGIFALILVVIFVSISPSQDIPVVAEYELNEETPAPESLSSTIDSKNPQLSETALQEALESTEPIITPPPELTPEQTFLVSIQNQIDDLANQYAGGIIKSLKFYLSTNLLMAELSNDWYNMTQEEQNKLVNQMFEEVQDLDFKKLILINSQGRTIARTSVINSYMIILERSLLKLPESFDSKE
>NC_008312.1|WP_011611929.1|3617963_3618434_-|SsrA-binding-protein-SmpB
MAKKSGEGQKIISDNRQARFNYHIIETYEAGVALQGTEVKSIREGKVNLRDGYALIRNNEAWLLNVHISPYQKAGDFFNHEPRRSRRLLLHKQEIRKLIGKVEQQGLTLVPLRMYFKRGWVKVDIALAQGKKLYDKRETIKRRDDKRAMQRAIKQY
>NC_008312.1|WP_011611927.1|3615411_3616089_+|hypothetical-protein
MSYYVYGFLYLPESCLALPKGMEKEVELVPYQNIAAVVEANVSIEAIQETEEKLLEAILAHDRVVREIFQQVSMLPLRFGNAFALRENIINDLQNNQQQYLNILTKLQQQAEYTITFTPVSYPSTLEVSKVRGKAYLLAKKQQFEQQQAFQTKQRQQWENIRQLIFKNYPKAVFRDSTESKIKQVHLLANRDARVITTEELSTWQTECSYWQITLSEQLPPYHFV
>NC_008312.1|WP_011611926.1|3614310_3615111_+|GvpL/GvpF-family-gas-vesicle-protein
MEFGFYVYGLIQEKGKMDESKDESKNGLKGSNESKDELKGLDKEDVKIQDVDEFAVLYSIAKKERYLASRRNLITHEKVLESAMEAGYRNLLPMQFGLVVSEWEKFSQDFTKPCEQQIHDLFTKLKNNREVGIKIYWEPDAELEKLLENDKDLKEERDSLKDKKLTMDQVIDIGQKIEQGMNERKQNIIEIFQETLNKMAIEVIENEVQTEKMIYNAAYLIPWDQEEDFGEKVETIDSKLCERGNFTIRYNSFTAPYNFARIRQQD
>NC_008312.1|WP_011611925.1|3613721_3613979_-|gas-vesicle-protein-GvpG
MLLRLLTLPISGPLEGVTWLGKKLQEQVDTEIDETENLSKKLLTLQLAFDMGEISEEDFEDQEEELLLAIQALEEQKLKEEEEDA
>NC_008312.1|WP_011611936.1|3628412_3630362_-|serine-protease
MKHITKLTVGLITIALVSCNKYESQISTDVSTKISRPDPIITPRQDNAPFNQIYIYRLAENITVEVVARSTVSGGDPFSSSGSGVIIGKQGSTYYVLTAKHIFQYQDDYRVVVRSKKPGEDAEILKLEIIYRYPDADLAVFKFASVKQYKVAEVGEASQLRKNSEVYVGGWPGAENREGFQFTPAKVTNPRAGDLLNYEPTVPGEGVYPGMSGGAVLNKAGQLMGIHVGLTKAGDGEGVLVSTFLRDIPQQVSRVLVRSTSAALPSPIPSPKNRAVGNTDNVTPSQIQNAESYYEQGDKHHDREEFEQALADYNQAIQLNPKYADAYNNRGIVYRKQGKYDLALADLNQAIQLNPKYADAYKNRGNVYYNQGKYDLALADYNQAIQLNPKYAEAYNNRGLVYDDQGKYDLAIAEFNQAIQLNPKYAYAYNNRGVVYDDQGKYDLALADYNQAIQLNPKYAEAYNNRGGVYLEQGKYDLAIADYNQAIQLNPKLAEAYNNRGAVYRKQGKYDLALADYNESIRLNNPQLWLPYNNRGLVYNDQRKYDLALADYSQAIQLNPKDAYAYYNRGNVYDDQGKYDLAIADYSQAIQLNPKYANAYYTRGLTNKDQRNMEKAISDFEKAADLYKQQGNQTWYQNSLDQLKELRGS
>NC_008312.1|WP_011611937.1|3631291_3631852_-|hypothetical-protein
MNFKFVQRWATISCFSLAVIFGLTHHSRAQQNGGLASFYCGTDNGKSATIADHPIRGKITLIIWESNYFINAGYDPQKRCRIISNRFNRFQSIGSLRKIVPSRTNNLPVLCALSSLDGYTGSCPNTNVLMTLKPGDNAQEMVNQMGELNLKDSVEPLRHSATIFEQYGDIKVLDINSMLRYSSPTK
>NC_008312.1|WP_011611938.1|3632058_3632676_-|hypothetical-protein
MLHRLRFLEIAEYVFIFASAVGIFVNYFWQKPIVYPLGLVLISLLINLVNRRNLGAQIKAIKFETTGKIDKYQDSISEIISELQNNIKSLKSTTEVLEIHQVEEKIQPLLETLKTLSNRLDIQEKTIKLLQAELNLFSQQFNQRPELKQINDLASVIVDLQQFINKLPEWSSLREQSFQKLEEKVNQALLKLEKNIAAEKRKTDN
>NC_008312.1|WP_011611939.1|3633779_3635186_-|magnesium-transporter
MIEKNKYSPPSITTISRQELRELVRSQLQTLLEQDNLSGAKALLVPVQPADIAEAIEGLPETMQVIAFRLLPKVEAIEVYEQLGSTVQQSLCEKFKRQEVIDIVDKMSPDDRVKLFEELPAAVVRRLLGQLSPTERQATAQLLGYDSGTAGRIMTPEYISLKEEYTVAESLERIRSLANVTETVYSLYVTDTNRYLTGILSLRDLVTSQLNQTIGEIMSRDFVSVQTGTDQEEVVRVIQRYDFLAIPVVDSEQRLVGIITVDDVLDILEQETTEDIYALGGVQSDGDNYFQVNLFTVARRRVVWLFVLLLTNSVTGGIITAQEDILKKVVTLAAFIPLLTGTGGNVGAQSSTVVIRGMNTDEIWKIGILKVIIREACAGAMLGSILGLLATAWAYLFIVNGNLEVSVTVGISLVAISTLASIAGSALPFLFRSFGLDPALMSAPFITTAVDVLGVLIYFNLARMILQI
>NC_008312.1|WP_011611940.1|3635608_3637234_-|sodium:proton-antiporter
MLESIIWILLTGFFVGEIALRLKAPPLIGMLLVGILLGPQISNTIDSSILEAADSLRTFAVTIILMKAGLGLDREKLAQQGSVALRLGFLPATCEAIVIALAAMWLLNFDFATGLLLGCIIGAESPAVIVPGMLRLKSLGWGVTKGIPDAILTGSALSDVLLLLIFSLLLAFLSQGTTIGITLPGGITINLLQILPFQVTLQIILGAIAGLLMAQILVLLLVKQNWTQNSTQDTLVAGSLTLLLVVLAEKFPIFSGYLAVMATGFFVLEFDPPLGRRLRNGFETLWTIAQIILFVLLGASIPLQVLENVFLVGLLILALGTFVGRMFGWYLSTLGSNWNLQERLFLLPGNSAKATVQAAIGAIPLAVGIEGGETILAIAALSILVTAPLGAWAIPALAPKLLEKGEVDPTKVAIARPIILLAAVDTSPLAVDVLLKAAELARRCDGEIVVLHVLQFEYRNSIEQLRQQTRQLLADIRHQFITVAGDASEEIIFIAQEYGAAEIVIGKKGDRLWDNVLVGSVSQAVLEKSLIPVVVVEKIKT
>NC_008312.1|WP_011611941.1|3638103_3639891_+|aspartate--tRNA-ligase
MRTHYCGQVNSNNIEETVNLCGWVDRRRDHGGVIFLDLRDRSGLIQIVSDPERTPDSYQIAGDIRNEYVVQITGRVSRRPEESLNPKLPTGEIEIYADDIQLLNGLGKQLPFQVSTAETEAVREELRLKYRYLDLRRERMTRNLLLRHEVIKAIRRFLEDEQNFVEIETPILTRSTPEGARDYLVPSRVHPGEWFALPQSPQLFKQILMVSGFDRYYQIARCFRDEDLRADRQPEFTQLDMEMSFMSQEEILQLNEKLVAYIFQKVKGIDLPLPFPRLTYTEAMERYGSDKPDVRFGLELVDVSDLMKDSGFKVFSGAIAKGGIVKVLPIPGGNDAISNVRIKPGGDLFKEASEVGAKGLAYVRVKEGGKIDTIGAIKDNLTDEQKQELLKRTNAQPGHLLLFAADDANTVNKTLDRLRLVIGEQLGLIDQDKISLLWVTDFPMFEWNEDEQRLEALHHPFTAPHPDDINDLKTARAQAYDLVFNGYEVGGGSLRIYQRDVQEKVFEAIGLSAQEADNKFGFLLEAFEYGTPPHGGIAYGLDRLVMLLAVEESIRDVIAFPKTQQAKCLLANAPSEVDKKQLKELHVSSISKAKS
>NC_008312.1|WP_011611942.1|3640630_3642940_-|TOMM-precursor-leader-peptide-binding-protein
MSNPQIKPHFHIEIIEPKHVYLLGENSTDALTGEFYCQLIPLLDGQHSFEEICETLAEIAYPEDVEYVLNRLKTKGYLTEATPELPPPAAAFWSLLNVEPQFASDCLQKNTVYIASVGETTTDLLIESLTAVGIKTKPWENYPLTSDRKALLVVLTDDYLQPQLKEINKTALSASQPWLLAKPVGGVLWLGPIFEPENTGCWECLSQRLRGHREVEATVLRQKEKSVVSSASKRDVTGCLPPPPVFLPSTLATGINLITTEVAKWIVKESGVEMPKFTTLAGKVVTFNQTDFSTTTHILSKRPQCEACGDSKLLQEMSSYPLSLSSRKKHFTTDGGHRAFTPDQTTKRYKKLISPITGVVSALVRVSDPENPLIHTYSAIHSFGAAKSLGALRRSLRHKSGGKGKSDRQSKASGFCEAIERYSGIFQGDEPRKKSTLAKLGKQGIHPERCLHFSPTQYANREELNANSKVAHDWIPQPFDASQEIEWTPVWSLTEETHKYLPTAWCYYAYKLPKKHNFCVADSNGNAAGNTIEEAILQGFMELVERDSVAIWWYNSLQRPGVDLASFDDPYLLEVQEFYEQNQRELWVLDLTTDLGIPAFTAVSRRVNEEYERVITGFGAHFDPKIAILRAVTEVNQIGLGMDQQDISQMEEGLQRWMTTATLESHPYLAPHPEIPAKVYGDYPKLWSDDIYDDVLTCVKIAQEAGMETLVLDQTRPDIELKVVKVIVPGLRHFWSRFGKGRLYDVPVKMGLLSAALQEEEMNSMPMVF
>NC_008312.1|WP_011611943.1|3643249_3643588_-|hypothetical-protein
MVLLYADENFPLPVVKNLTNMGYNVLTAQAAGKANLQIPDEEVLAFAVNNGRAVLTRNRRDFIQLHIANSNHEGIIVCTEDSNFVGVANRIHGTISTTESLKNKLIRINRSS
>NC_008312.1|WP_011611944.1|3643589_3643964_-|DUF433-domain-containing-protein
MEITLDPELEKFIRNQVQSGQYCSLDEAINVALRLLATQTLASQGINKTPNVCGGDACVGKTRIPVWSLVSDRRLGMSDPEILAAFPTLSAVDLVNAWVYAERHLEEIESAIRENEVIMETEVE
>NC_008312.1|WP_155994394.1|3644125_3644323_+|hypothetical-protein
MIIRLETERSLPSTSLQIVQKIWVQHDGTEDAIADQLVEKGVPAEDIVLAYHPPLLRKYTEFAES

Crispr_ID: NC_008312_28

• CRISPR_ID: NC_008312_28
• CRISPR_location: 3650625-3650737
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NC_008312_28

Consensus_repeat	Method
ATCTGAGTTATATGTGGGATAATTATA	CRISPRCasFinder

spacers of NC_008312_28

>28.1|3650652|59|NC_008312|CRISPRCasFinder
TTGCCAAAGCTAAAGCCTCACTACAAACAAAAATAGTTACCACCCCAACCAGAAGACAT

CRISPR arrays and Neighbor proteins around NC_008312_28

CRISPR arrays

The CRISPR arrays of NC_008312_28

>merge|NC_008312|28|3650625-3650737|CRISPRCasFinder
ATCTGAGTTATATGTGGGATAATTATATTGCCAAAGCTAAAGCCTCACTACAAACAAAAATAGTTACCACCCCAACCAGAAGACATGATCTGATTATATGTGGGATAATTATA

>NC_008312|28|23|3650625-3650737|CRISPRCasFinder
ATCTGAGTTATATGTGGGATAATTATA	TTGCCAAAGCTAAAGCCTCACTACAAACAAAAATAGTTACCACCCCAACCAGAAGACAT
GATCTGATTATATGTGGGATAATTATA

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_008312.1|WP_044136736.1|3656183_3656402_-|hypothetical-protein	unknown	unknown	unknown
NC_008312.1|WP_011611952.1|3651036_3653145_+|PatA/PatG-family-cyanobactin-maturation-protease	unknown	unknown	gnl|CDD|274838
NC_008312.1|WP_011611956.1|3659572_3659785_-|hypothetical-protein	unknown	unknown	unknown
NC_008312.1|WP_011611957.1|3659860_3660556_-|hypothetical-protein	unknown	unknown	unknown
NC_008312.1|WP_011611949.1|3647883_3649884_+|PatA/PatG-family-cyanobactin-maturation-protease	unknown	unknown	gnl|CDD|274838
NC_008312.1|WP_044137423.1|3663416_3664739_+|DUF697-domain-containing-protein	unknown	unknown	gnl|CDD|226125
NC_008312.1|WP_011611950.1|3650113_3650326_-|cyanobactin-biosynthesis-PatC/TenC/TruC-family-protein	unknown	unknown	gnl|CDD|275240
NC_008312.1|WP_155994394.1|3644125_3644323_+|hypothetical-protein	unknown	unknown	gnl|CDD|341357
NC_008312.1|WP_011611954.1|3656449_3657214_-|protein-phosphatase-2C-domain-containing-protein	unknown	unknown	gnl|CDD|379325
NC_008312.1|WP_011611944.1|3643589_3643964_-|DUF433-domain-containing-protein	unknown	unknown	gnl|CDD|225291
NC_008312.1|WP_011611955.1|3657637_3658300_-|VWA-domain-containing-protein	unknown	unknown	gnl|CDD|226696
NC_008312.1|WP_044136730.1|3646964_3647168_-|microcyclamide/patellamide-family-RiPP	unknown	unknown	unknown
NC_008312.1|WP_011611953.1|3654023_3655592_-|lysine--tRNA-ligase	unknown	unknown	gnl|CDD|234778
NC_008312.1|WP_155994395.1|3653337_3653553_+|hypothetical-protein	unknown	unknown	unknown
NC_008312.1|WP_011611941.1|3638103_3639891_+|aspartate--tRNA-ligase	unknown	unknown	gnl|CDD|234775
NC_008312.1|WP_011611943.1|3643249_3643588_-|hypothetical-protein	unknown	unknown	gnl|CDD|375906
NC_008312.1|WP_011611942.1|3640630_3642940_-|TOMM-precursor-leader-peptide-binding-protein	unknown	unknown	gnl|CDD|376866
NC_008312.1|WP_011611946.1|3644580_3646008_+|SagB/ThcOx-family-dehydrogenase	unknown	unknown	gnl|CDD|188352
NC_008312.1|WP_011611958.1|3660871_3662839_+|acetate--CoA-ligase	unknown	unknown	gnl|CDD|234677
NC_008312.1|WP_011611940.1|3635608_3637234_-|sodium:proton-antiporter	unknown	unknown	gnl|CDD|223104

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_008312.1|WP_011611940.1|3635608_3637234_-|sodium:proton-antiporter	gnl|CDD|223104	COG0025, NhaP, NhaP-type Na+/H+ and K+/H+ antiporters [Inorganic ion transport and metabolism].	2.02898e-42
NC_008312.1|WP_011611949.1|3647883_3649884_+|PatA/PatG-family-cyanobactin-maturation-protease	gnl|CDD|274838	TIGR03895, hypothetical_protein, cyanobactin maturation protease, PatA/PatG family. This model describes a protease domain associated with the maturation of various members of the cyanobactin family of ribosomally produced, heavily modified bioactive metabolites. Members include the PatA protein and C-terminal domain of the PatG protein of Prochloron didemni, TenA and a region of TenG from Nostoc spongiaeforme var. tenue, etc.	0
NC_008312.1|WP_044137423.1|3663416_3664739_+|DUF697-domain-containing-protein	gnl|CDD|226125	COG3597, COG3597, Uncharacterized protein/domain associated with GTPases [Function unknown].	4.59049e-58
NC_008312.1|WP_011611950.1|3650113_3650326_-|cyanobactin-biosynthesis-PatC/TenC/TruC-family-protein	gnl|CDD|275240	TIGR04447, hypothetical_protein, cyanobactin cluster PatC/TenC/TruC protein. Members of this family usually are small proteins (PatC, TenC, TruC) of unknown function in cyanobactin (prenylated cyclic peptide) biosynthesis clusters, where a different small protein is a known cyanobactin precursor (patellamide, anacyclamide, piricyclamide, etc). They may instead be the C-terminal domain of a longer protein that otherwise consists mostly of lectin-like or VWF type A domains, in similar context. Similar to the cyanobactin precursors, members of this family have two very strongly conserved regions separated by a hypervariable region, suggesting these proteins may undergo a similar maturation.	3.44069e-09
NC_008312.1|WP_155994394.1|3644125_3644323_+|hypothetical-protein	gnl|CDD|341357	cd16382, XisI-like, XisI is FdxN element excision controlling factor protein. This family contains XisI proteins, also known as FdxN element excision controlling factors, and similar proteins. FdxN element is excised from the chromosome during heterocyst differentiation in cyanobacteria. This is accomplished by the large serine recombinase XisF (fdxN element site-specific recombinase). The xisH as well as the xisF and xisI genes are required. XisI may function as recombination directionality factor (RDF), and needs XisH which may function as an endonuclease.	2.17131e-24
NC_008312.1|WP_011611952.1|3651036_3653145_+|PatA/PatG-family-cyanobactin-maturation-protease	gnl|CDD|274838	TIGR03895, hypothetical_protein, cyanobactin maturation protease, PatA/PatG family. This model describes a protease domain associated with the maturation of various members of the cyanobactin family of ribosomally produced, heavily modified bioactive metabolites. Members include the PatA protein and C-terminal domain of the PatG protein of Prochloron didemni, TenA and a region of TenG from Nostoc spongiaeforme var. tenue, etc.	0
NC_008312.1|WP_011611944.1|3643589_3643964_-|DUF433-domain-containing-protein	gnl|CDD|225291	COG2442, COG2442, Uncharacterized conserved protein [Function unknown].	2.88512e-19
NC_008312.1|WP_011611954.1|3656449_3657214_-|protein-phosphatase-2C-domain-containing-protein	gnl|CDD|379325	pfam13672, PP2C_2, Protein phosphatase 2C. Protein phosphatase 2C is a Mn++ or Mg++ dependent protein serine/threonine phosphatase.	3.12707e-60
NC_008312.1|WP_011611955.1|3657637_3658300_-|VWA-domain-containing-protein	gnl|CDD|226696	COG4245, TerY, Uncharacterized protein encoded in toxicity protection region of plasmid R478, contains von Willebrand factor (vWF) domain [General function prediction only].	1.00221e-78
NC_008312.1|WP_011611941.1|3638103_3639891_+|aspartate--tRNA-ligase	gnl|CDD|234775	PRK00476, aspS, aspartyl-tRNA synthetase; Validated.	0
NC_008312.1|WP_011611943.1|3643249_3643588_-|hypothetical-protein	gnl|CDD|375906	pfam18480, DUF5615, Domain of unknown function (DUF5615). This is a domain of unknown function found in potential toxin-antitoxin system component.	1.04212e-21
NC_008312.1|WP_011611942.1|3640630_3642940_-|TOMM-precursor-leader-peptide-binding-protein	gnl|CDD|376866	pfam02624, YcaO, YcaO cyclodehydratase, ATP-ad Mg2+-binding. YcaO is an ATP- an Mg2+-binding protein involved in the peptidic biosynthesis of azoline. There three motifs involved in the binding are, in UniProtKB:P75838, 71-79: Sx3ExxER, 184-203: Sx6Ex3Qx3ExxER, and 286-290: RxxxE. Three slightly different functional families are represented in this family, proteins involved in TOMM (thiazole/oxazole-modified microcin) biogenesis, non-TOMM proteins such as UniProtKB:P75838, and TfuA-associated non-TOMM proteins involved in trifolitoxin biosynthesis. UniProtKB:P75838 hydrolyzes ATP to AMP and pyrophosphate.	9.63006e-116
NC_008312.1|WP_011611946.1|3644580_3646008_+|SagB/ThcOx-family-dehydrogenase	gnl|CDD|188352	TIGR03605, antibiot_sagB, SagB-type dehydrogenase domain. SagB of Sterptococcus pyogenes participates in the maturation of streptolysin S from a ribosomally produced precursor polypeptide. Chemically similar systems operate on highly diverse sets of bacteriocin precursors in numerous other bacteria. This model describes a domain within SgaB and homologous regions from other proteins, many of which appear to be involved in biosynthesis of secondary metabolites. While some substrates may be intermediates in non-ribosomal peptide syntheses, others are involved in heterocycle-containing bacteriocin biosynthesis, and can be found near SgaC-like (see TIGR03603, cyclodehydratase) and SgaD-like (see TIGR03604, "docking") proteins. Members of this domain family are heterogeneous in length, as many have a partial second copy of the domain represented here. The incomplete second domain scores below the cutoffs to this model in most cases.	3.35239e-78
NC_008312.1|WP_011611958.1|3660871_3662839_+|acetate--CoA-ligase	gnl|CDD|234677	PRK00174, PRK00174, acetyl-CoA synthetase; Provisional.	0
NC_008312.1|WP_011611953.1|3654023_3655592_-|lysine--tRNA-ligase	gnl|CDD|234778	PRK00484, lysS, lysyl-tRNA synthetase; Reviewed.	0

Protein sequences

>NC_008312.1|WP_011611950.1|3650113_3650326_-|cyanobactin-biosynthesis-PatC/TenC/TruC-family-protein
MSKKDVKKTPQAKSEITSPPSQPVQQPELKIEENTILATGLEDYGRWKGMFQDQKREGKPPFPRRGRIWA
>NC_008312.1|WP_011611949.1|3647883_3649884_+|PatA/PatG-family-cyanobactin-maturation-protease
MPEISSIPGIKQLWAKTKGNSEVCVAVLDGLVDLKHPCFEGANLTQLPSLVQGQATPQSEMSLHGTHVASIIFGQPNSSVSGIAPHCRGLIVPIFSDYHRRTSQLNLARAIEQAVNAGANIINISGGELTDYGEAEDWLNRAVSLCQNNNVLLVAAAGNDGCECLHVPAALPTVLAAGAMGENGQPLDYSNWGENYQTQGILALGENILGAEPGGGTRQLSGTSFATPVVSGVAALLMSLQLQREEKPDSQKVRTALLKTAVPCHAQEKRRCLVGQMNISGAIAHITGETMSESEQDNSNGIEASCGCESTPEASLPGSVGLENSLPTPADNGVVAAGVVEAGVTASQPLSSTNTSNTSNNQISAMPNNSQSNNSNGITPSQPPQDVTNIVYVIGTLGYDFGTEARRDSFKQLMPAVTIGNTQIPANPYDARQMVDYLANNLSEAKSLIWTLNMELTPIYAIEAVGSFAREVYEALQELLAGEVEAEDAERYIERVSIPGKLTGRTVKLFSGQVVPVIEPVSPRGIYGWRVNTLVGSALEAVRGEQAEADDEQMRRSLSSFLNRVYYDLRNLGQTSQDRALNFAATNAFQAAQTFSTAVAAGMELDSIAVTKSPFCRMDSDCWDVQLKFFDPENNRRAKKVFRFTIDVSDFIPVTLGEVRSWSSPY
>NC_008312.1|WP_044136730.1|3646964_3647168_-|microcyclamide/patellamide-family-RiPP
MGKKNIQPNSSQPVFRSLVARPALEELREENLTEGNQGHGPLANGPGPSGDGLHPRLCSCSYDGDDE
>NC_008312.1|WP_011611946.1|3644580_3646008_+|SagB/ThcOx-family-dehydrogenase
MTSSLFTLSLTSLVTLIHEDDNIILQAPIRSPLKKTTPTRQVKFEHPSSGLISALNHLKSSQKTYPQLKALVVAADGEEAGERFDVELEKLINTGWVSHSLYPLATVIPIVEKNYRFKSPEIAQLQGKFTLSRFAYLHQSQGKTIIECPLSTSQIIALDWRCGALLAKLSQPQTPSSLSADIPDITEEIAQKFLALLMATQMLSPETEPTPLMYWEFHDLLFHSRSRIGRHNNPTGGTMRFFGKTEPLPIVKPPMSDKVIKLVQPNLEYLTQIDIPLTKALELRQSIREYDEQPIRLQQLGKLLYCCARIKKIETMETEEFGTLHLNYRPYPCGGAIYELEIYPVVNRCQGLAAGVYHYQPLEHCLYQISAHETQVEALIEDAYKSSGEQDQPQVLLVITARFGRIFWKYESIAYALILKHVGVLYQTFYLMATGMHLAPCALGIGDADNFAQITGLDYYEESSVGEFLLGSVRN
>NC_008312.1|WP_155994394.1|3644125_3644323_+|hypothetical-protein
MIIRLETERSLPSTSLQIVQKIWVQHDGTEDAIADQLVEKGVPAEDIVLAYHPPLLRKYTEFAES
>NC_008312.1|WP_011611944.1|3643589_3643964_-|DUF433-domain-containing-protein
MEITLDPELEKFIRNQVQSGQYCSLDEAINVALRLLATQTLASQGINKTPNVCGGDACVGKTRIPVWSLVSDRRLGMSDPEILAAFPTLSAVDLVNAWVYAERHLEEIESAIRENEVIMETEVE
>NC_008312.1|WP_011611943.1|3643249_3643588_-|hypothetical-protein
MVLLYADENFPLPVVKNLTNMGYNVLTAQAAGKANLQIPDEEVLAFAVNNGRAVLTRNRRDFIQLHIANSNHEGIIVCTEDSNFVGVANRIHGTISTTESLKNKLIRINRSS
>NC_008312.1|WP_011611942.1|3640630_3642940_-|TOMM-precursor-leader-peptide-binding-protein
MSNPQIKPHFHIEIIEPKHVYLLGENSTDALTGEFYCQLIPLLDGQHSFEEICETLAEIAYPEDVEYVLNRLKTKGYLTEATPELPPPAAAFWSLLNVEPQFASDCLQKNTVYIASVGETTTDLLIESLTAVGIKTKPWENYPLTSDRKALLVVLTDDYLQPQLKEINKTALSASQPWLLAKPVGGVLWLGPIFEPENTGCWECLSQRLRGHREVEATVLRQKEKSVVSSASKRDVTGCLPPPPVFLPSTLATGINLITTEVAKWIVKESGVEMPKFTTLAGKVVTFNQTDFSTTTHILSKRPQCEACGDSKLLQEMSSYPLSLSSRKKHFTTDGGHRAFTPDQTTKRYKKLISPITGVVSALVRVSDPENPLIHTYSAIHSFGAAKSLGALRRSLRHKSGGKGKSDRQSKASGFCEAIERYSGIFQGDEPRKKSTLAKLGKQGIHPERCLHFSPTQYANREELNANSKVAHDWIPQPFDASQEIEWTPVWSLTEETHKYLPTAWCYYAYKLPKKHNFCVADSNGNAAGNTIEEAILQGFMELVERDSVAIWWYNSLQRPGVDLASFDDPYLLEVQEFYEQNQRELWVLDLTTDLGIPAFTAVSRRVNEEYERVITGFGAHFDPKIAILRAVTEVNQIGLGMDQQDISQMEEGLQRWMTTATLESHPYLAPHPEIPAKVYGDYPKLWSDDIYDDVLTCVKIAQEAGMETLVLDQTRPDIELKVVKVIVPGLRHFWSRFGKGRLYDVPVKMGLLSAALQEEEMNSMPMVF
>NC_008312.1|WP_011611941.1|3638103_3639891_+|aspartate--tRNA-ligase
MRTHYCGQVNSNNIEETVNLCGWVDRRRDHGGVIFLDLRDRSGLIQIVSDPERTPDSYQIAGDIRNEYVVQITGRVSRRPEESLNPKLPTGEIEIYADDIQLLNGLGKQLPFQVSTAETEAVREELRLKYRYLDLRRERMTRNLLLRHEVIKAIRRFLEDEQNFVEIETPILTRSTPEGARDYLVPSRVHPGEWFALPQSPQLFKQILMVSGFDRYYQIARCFRDEDLRADRQPEFTQLDMEMSFMSQEEILQLNEKLVAYIFQKVKGIDLPLPFPRLTYTEAMERYGSDKPDVRFGLELVDVSDLMKDSGFKVFSGAIAKGGIVKVLPIPGGNDAISNVRIKPGGDLFKEASEVGAKGLAYVRVKEGGKIDTIGAIKDNLTDEQKQELLKRTNAQPGHLLLFAADDANTVNKTLDRLRLVIGEQLGLIDQDKISLLWVTDFPMFEWNEDEQRLEALHHPFTAPHPDDINDLKTARAQAYDLVFNGYEVGGGSLRIYQRDVQEKVFEAIGLSAQEADNKFGFLLEAFEYGTPPHGGIAYGLDRLVMLLAVEESIRDVIAFPKTQQAKCLLANAPSEVDKKQLKELHVSSISKAKS
>NC_008312.1|WP_011611940.1|3635608_3637234_-|sodium:proton-antiporter
MLESIIWILLTGFFVGEIALRLKAPPLIGMLLVGILLGPQISNTIDSSILEAADSLRTFAVTIILMKAGLGLDREKLAQQGSVALRLGFLPATCEAIVIALAAMWLLNFDFATGLLLGCIIGAESPAVIVPGMLRLKSLGWGVTKGIPDAILTGSALSDVLLLLIFSLLLAFLSQGTTIGITLPGGITINLLQILPFQVTLQIILGAIAGLLMAQILVLLLVKQNWTQNSTQDTLVAGSLTLLLVVLAEKFPIFSGYLAVMATGFFVLEFDPPLGRRLRNGFETLWTIAQIILFVLLGASIPLQVLENVFLVGLLILALGTFVGRMFGWYLSTLGSNWNLQERLFLLPGNSAKATVQAAIGAIPLAVGIEGGETILAIAALSILVTAPLGAWAIPALAPKLLEKGEVDPTKVAIARPIILLAAVDTSPLAVDVLLKAAELARRCDGEIVVLHVLQFEYRNSIEQLRQQTRQLLADIRHQFITVAGDASEEIIFIAQEYGAAEIVIGKKGDRLWDNVLVGSVSQAVLEKSLIPVVVVEKIKT
>NC_008312.1|WP_011611952.1|3651036_3653145_+|PatA/PatG-family-cyanobactin-maturation-protease
MPDFADIPGLTKLWTHTKGDPRITVALLDGTADIERGCFQGANVTKINSYWQEAIELDPKDIDTYREIQNSDEKSEVKQAKLKEAIPDEITLQILGAAFHATHVFSNIFGQPGTPVEGIAYKCRGINIPLGYGNDYYIDPINLARGINLAVDLGANIIHCAACRPNQTGIGHEILEKAVRQAQENNVLIVAPTGNNKGECWCLPAILPGVMSVGAMKDNGQVFKFSNWGGQYQQQGIIAPGENILGAQPGTEETVRQKGTSCAAPMVTAISALLMSLQLQQGASPDAEAVRAALTNSAIPCTLEDTEEIERCMLGKLNVAGAYQLLTGKQLEAVGVSAAEATSEEDVILEDSGVDVGEVIVDETSVVPAQENAPISFSLPVGENRESLTNVATNITAASGVEQNNIKPTKVSQTAHGVTPSARSNMIYALGTLGYDFGTEARRDSFKQLMPAVILNGVQVPANPYDGRQMADYLDANLYEGKSLIWTFNIELTPIYALRPVGAFADDIYETLQNMLAGEVEAEDHEDYIDRVSITGRLTDQTVKLFSGQTLPVVKINSPRGMYGWTVNSLIDNALESVRTEQTEAEEEAIRKSLRSFLQRVYYDLRNLGQADRDRAINFAATNAFQATATISEAVAIGMELHSIEVEKSPFCRYNSNCWDVKLKFFNPDNSRRAKRVYRFTIDVSDLMPVTLGKVRSWSVPK
>NC_008312.1|WP_155994395.1|3653337_3653553_+|hypothetical-protein
MSTDNRVARERMTPASQMGSLDILKKVDSQLTGSVHQRHKNIPRCDSYKCLGRITNLVVLYSNGQVKIVSL
>NC_008312.1|WP_011611953.1|3654023_3655592_-|lysine--tRNA-ligase
MAKSETRNEVEVRSQKVDELRAQGIDPYPSQAIERSHTTKQVIDLFSPPAKELEPGETDPNEKFLKVCGRITSKRDSGSIGFINLTDETGKIQLKIEKKLVKGDPGLSFKQVQKLLDVGDFVSAEGIGCRTNRGELSIQVNKLDVLSKAIIPFPDSYYGVNDPEICRRHREMDLAGNAEALQRFRVRSKIMQSIRTYLWDANFYEIETPILQSIYGGAAARPFVTHHNALDVDLYLRIATELFLKRAICGGFERVFELGRVFRNEGIDSTHNPEFTSLEVYQAYADYFEILGLVEDVICYSLTNILGDLKQIEYQGQTISLERQYDYSQKYPNFTGKHWQVKTMVEAVKDETGLDFDNLELPEAIRAAEKLNLKLSKLETQSLGYLLYAVFDQKVESTLIQPTFVIDFPVEVSPLAKRHHSKPGFVERFELFIHGTEYSNGFSELNDPQDQRQRFEEQIAQREAGDDEAHPMDEDFIQALSLGMPNCGGMGIGVDRLVMLLTNTQSIRDVIMFPTMRSTLKD
>NC_008312.1|WP_044136736.1|3656183_3656402_-|hypothetical-protein
MSEILLAPIEFELPELSRLKILWEYFLFEVVPRSQVINSQWLAQRSTELGGGDIWNLVRLTRSSGVSRISDI
>NC_008312.1|WP_011611954.1|3656449_3657214_-|protein-phosphatase-2C-domain-containing-protein
MSIEAEIKWRVISVSVAGKSHEKRGQLCQDAHHWQILPEGILVAAVADGAGSSNLGDVGAKIAVGVAVEAISQQKLLPVDDVGWQFLLVDTLKAAKNAVLAESRVREVEGRELAATLILVVATPEFAIAAQVGDGAAVVGDGEENIFPVTSPQTGEHVNETTFLISEQGVENAQVNIWRGKLVHLAIFSDGLQMLALKMPMGLPHSPFFAPLFKFMTVVTNEEEANKQLEDFLRSPKVTGRTDDDLTLLLARYG
>NC_008312.1|WP_011611955.1|3657637_3658300_-|VWA-domain-containing-protein
MRLDELVEFAENPEPRCPCVLLLDTSASMTGTPIKALNDGLETFRDNLITDDLAKKRVEVAIISFDNQVKIVQDFITADQFENPILTAQGQTYMGTAIHKALDMIAARKSEYRNNGITYYRPWVFLITDGEPQGESEKVFKEAGDRIKQEEDNKHVAFFAVGVEGANMDKLGEIVQRTPLKLRGLNFREMFIWLSASMQQVSHSKVDEQVALPPPGWGAV
>NC_008312.1|WP_011611956.1|3659572_3659785_-|hypothetical-protein
MVTTGTTLSNKERLEKAWQAFQAVQNLQEDRLTWGINHVSLYVENIDGDWLENWGEEDEEELTEKLLLRK
>NC_008312.1|WP_011611957.1|3659860_3660556_-|hypothetical-protein
MQAREIEPKLKQLSRLAWSTEPALAQRLDEVRRWIKDIRPGSLTQKRLLVGFLLELIKDGEFWLKLQSLTNEERQIFLQHLPSPITYWYESLFPKWFNKNDHKFYIWKQKLRSGEFNQKDAQLIESIARQIKSRDGFVVHRYIADLSMATDVIVSSNTGKPLCVQLTTISGEFCNYKYKEWKDTLQQWKIRRGIFVSYNPSQDRSVIQLVNLILHNSKHLKEAKYIKFCFR
>NC_008312.1|WP_011611958.1|3660871_3662839_+|acetate--CoA-ligase
MSELTIESILQEKRLFQPPEKFVQTAQIKGIEQYKELYEKAKSNPEEFWAELAETELDWFQKWDKVLEWQPPFAKWFINGKINISYNCLDRHLTTWRRNKAALIWEGEPGDSRTITYAQLHREVCQMANVFKQLGVKKGDRVGIYMPMIPEAAIAMLACARIGAPHTVVFGGFSADALKNRLVDAEAKLVVTADGGWRKDAIVPLKEQVDKALMAGAPSVENVLVVKRTAQKIQMEPGRDHWWHDLQKSASGECPAEPMDSEDMLFILYTSGTTGTPKGVVHTTGGYNLYTHVTNKWAFDLQDTDVYWCTADVGWITGHSYIVYGPLSNGATTLMYEGAPRASNPGCLWDVVEKYGVTIFYTAPTAIRALMKMGEQHPNSRNLTSLRLLGTVGEPINPEAWIWYHRVIGDSKCPIVDTWWQTETGGFMITPLPGATPTKPGSATFPFPGIIADIVNEEGESVDGNNGGYLVVKHPWPGMMRTVYGDPDRFRRTYWEYLRPKNGEYIYFAGDGAHKDEDGYFWVMGRVDDVINVAGHRLGTMEVESALVSHPAVAEAAVVGKPDEVKGEDIVAFVSLEGGREPDENLEKELKQHVVKEIGAIARPGEIRFTDDLPKTRSGKIMRRLLRSLAAGQEITGDTSTLQDRSVLDKLRAGS
>NC_008312.1|WP_044137423.1|3663416_3664739_+|DUF697-domain-containing-protein
MTETNDINSPAANSEQSTQTTQDVKTKSKIDSWQSHVSGIWNDTNKRFMKLLPIGKARQTIMQWFTVDEAEVAKILVKVRAELPTTEAILIGKPQTGKSSIVRGLTGVSKEIIGQGFRPQTQHTQRYAYPSDDLPLLIFTDTVGLGDVKQETPIIIHELLAELQQESNRARILILTVKINDFATDTLRQVAQQLRQEYPNIPCLLAVTCLHEVYPHSTEDHPEYPPEYEELQRAFATIKEDFAELYNSSVLLDFTLEEDGYNPVFYGLEAFRDNLAQLLPEAEARTIHQLLDEQTSKQLGNIYRDVARRYILSFTIMAATAAAVPLPFATMPVLTALQVSMVGLLGNLYGQTISPSQAGGVVSAIGGGFLAQAVGRELIKFVPGLGSAIAASWVAAYTWALGESACVYFGDLMGGKKPDPQKIQGVMQEAFESAQERFKG

Crispr_ID: NC_008312_29

• CRISPR_ID: NC_008312_29
• CRISPR_location: 3671484-3671793
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 4 spacers

Consensus repeat of NC_008312_29

Consensus_repeat	Method
AATATTAATAGTGCTCAAGCTAAGGTTGACATTGCTG	CRISPRCasFinder

spacers of NC_008312_29

>29.1|3671521|26|NC_008312|CRISPRCasFinder
AAGCGAATATTGATAGTGCTCAAGCT
>29.2|3671584|26|NC_008312|CRISPRCasFinder
AAGCTAAGGTTGACATTGCTGGATCA
>29.3|3671647|47|NC_008312|CRISPRCasFinder
AAGCAAGTCTCAGTAGTACAATAGCTCAACTACGGAGTGCAGAGGCT
>29.4|3671731|26|NC_008312|CRISPRCasFinder
AAGCAGAAGTTAATAGTGCATTATCC

CRISPR arrays and Neighbor proteins around NC_008312_29

CRISPR arrays

The CRISPR arrays of NC_008312_29

>merge|NC_008312|29|3671484-3671793|CRISPRCasFinder
AATATTAATAGTGCTCAAGCTAAGGTTGACATTGCTGAAGCGAATATTGATAGTGCTCAAGCTAAGGTTGACATTGCTGAAGCGAATATTGATAGTGCTCAAGCTAAGGTTGACATTGCTGGATCAAATGTTAGGAGTGCAGAAGCTAGGGTAGAAAGTGCACAAGCAAGTCTCAGTAGTACAATAGCTCAACTACGGAGTGCAGAGGCTAAAGTTAATAGTGCTAAAGCTAATATTAGTAGCGCTCAAGCAGAAGTTAATAGTGCATTATCCAATATTAATAGTGCTATGTCAAGTGTTAGCAGTGACG

>NC_008312|29|24|3671484-3671793|CRISPRCasFinder
AATATTAATAGTGCTCAAGCTAAGGTTGACATTGCTG	AAGCGAATATTGATAGTGCTCAAGCT
AAGGTTGACATTGCTGAAGCGAATATTGATAGTGCTC	AAGCTAAGGTTGACATTGCTGGATCA
AATGTTAGGAGTGCAGAAGCTAGGGTAGAAAGTGCAC	AAGCAAGTCTCAGTAGTACAATAGCTCAACTACGGAGTGCAGAGGCT
AAAGTTAATAGTGCTAAAGCTAATATTAGTAGCGCTC	AAGCAGAAGTTAATAGTGCATTATCC
AATATTAATAGTGCTATGTCAAGTGTTAGCAGTGACG

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_008312.1|WP_044137434.1|3685332_3686040_+|5'/3'-nucleotidase-SurE	unknown	unknown	gnl|CDD|234732
NC_008312.1|WP_044136736.1|3656183_3656402_-|hypothetical-protein	unknown	unknown	unknown
NC_008312.1|WP_044136738.1|3687914_3688112_+|hypothetical-protein	unknown	unknown	unknown
NC_008312.1|WP_044137425.1|3665249_3666287_+|hypothetical-protein	unknown	unknown	unknown
NC_008312.1|WP_155994396.1|3668885_3669755_+|hypothetical-protein	unknown	unknown	unknown
NC_008312.1|WP_011611966.1|3676130_3676451_+|hypothetical-protein	unknown	unknown	unknown
NC_008312.1|WP_011611968.1|3679357_3679600_-|hypothetical-protein	unknown	unknown	unknown
NC_008312.1|WP_044137423.1|3663416_3664739_+|DUF697-domain-containing-protein	unknown	unknown	gnl|CDD|226125
NC_008312.1|WP_011611954.1|3656449_3657214_-|protein-phosphatase-2C-domain-containing-protein	unknown	unknown	gnl|CDD|379325
NC_008312.1|WP_011611955.1|3657637_3658300_-|VWA-domain-containing-protein	unknown	unknown	gnl|CDD|226696
NC_008312.1|WP_011611957.1|3659860_3660556_-|hypothetical-protein	unknown	unknown	unknown
NC_008312.1|WP_011611970.1|3680799_3685065_-|tetratricopeptide-repeat-protein	unknown	unknown	gnl|CDD|274350
NC_008312.1|WP_011611965.1|3672571_3675706_+|efflux-RND-transporter-permease-subunit	unknown	unknown	gnl|CDD|223911
NC_008312.1|WP_044137430.1|3679707_3680367_+|HEAT-repeat-domain-containing-protein	unknown	unknown	gnl|CDD|224331
NC_008312.1|WP_052845780.1|3686720_3686966_-|hypothetical-protein	unknown	unknown	unknown
NC_008312.1|WP_011611967.1|3676729_3678637_+|hypothetical-protein	unknown	unknown	gnl|CDD|226124
NC_008312.1|WP_011611956.1|3659572_3659785_-|hypothetical-protein	unknown	unknown	unknown
NC_008312.1|WP_155994397.1|3686925_3687192_-|hypothetical-protein	unknown	unknown	unknown
NC_008312.1|WP_011611958.1|3660871_3662839_+|acetate--CoA-ligase	unknown	unknown	gnl|CDD|234677
NC_008312.1|WP_011611953.1|3654023_3655592_-|lysine--tRNA-ligase	unknown	unknown	gnl|CDD|234778

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_008312.1|WP_044137434.1|3685332_3686040_+|5'/3'-nucleotidase-SurE	gnl|CDD|234732	PRK00346, surE, 5'(3')-nucleotidase/polyphosphatase; Provisional.	1.00109e-85
NC_008312.1|WP_011611970.1|3680799_3685065_-|tetratricopeptide-repeat-protein	gnl|CDD|274350	TIGR02917, TPR_domain_protein, putative PEP-CTERM system TPR-repeat lipoprotein. This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.	9.67759e-46
NC_008312.1|WP_011611965.1|3672571_3675706_+|efflux-RND-transporter-permease-subunit	gnl|CDD|223911	COG0841, AcrB, Cation/multidrug efflux pump [Defense mechanisms].	0
NC_008312.1|WP_044137430.1|3679707_3680367_+|HEAT-repeat-domain-containing-protein	gnl|CDD|224331	COG1413, COG1413, FOG: HEAT repeat [Energy production and conversion].	7.29636e-20
NC_008312.1|WP_011611958.1|3660871_3662839_+|acetate--CoA-ligase	gnl|CDD|234677	PRK00174, PRK00174, acetyl-CoA synthetase; Provisional.	0
NC_008312.1|WP_011611967.1|3676729_3678637_+|hypothetical-protein	gnl|CDD|226124	COG3596, COG3596, Predicted GTPase [General function prediction only].	2.96771e-85
NC_008312.1|WP_044137423.1|3663416_3664739_+|DUF697-domain-containing-protein	gnl|CDD|226125	COG3597, COG3597, Uncharacterized protein/domain associated with GTPases [Function unknown].	4.59049e-58
NC_008312.1|WP_011611955.1|3657637_3658300_-|VWA-domain-containing-protein	gnl|CDD|226696	COG4245, TerY, Uncharacterized protein encoded in toxicity protection region of plasmid R478, contains von Willebrand factor (vWF) domain [General function prediction only].	1.00221e-78
NC_008312.1|WP_011611954.1|3656449_3657214_-|protein-phosphatase-2C-domain-containing-protein	gnl|CDD|379325	pfam13672, PP2C_2, Protein phosphatase 2C. Protein phosphatase 2C is a Mn++ or Mg++ dependent protein serine/threonine phosphatase.	3.12707e-60
NC_008312.1|WP_011611953.1|3654023_3655592_-|lysine--tRNA-ligase	gnl|CDD|234778	PRK00484, lysS, lysyl-tRNA synthetase; Reviewed.	0

Protein sequences

>NC_008312.1|WP_155994396.1|3668885_3669755_+|hypothetical-protein
MTNNVYDNDYYYERVVEEVYPHLEKQERGLLYRAIQIIHGEEKSQTPKNTQDICKSLDINANADKKDDVKKAKQFLIGRLEKYYLDNKDQNILQKIGNVWEYREKTTSKKIQAGDDKMIEIRLIIIGACTLVGFLACRDYLDKERKKSERKKVISQERKEQPSPPPIPASLCLVVPARIASTLETNSSLLSVNSVKYLIDNTAYFLCTTCKVADSNEQEYLKIAKEKEILPNSQRDVYIRIDINSGGKNLIDKKNRLALKNNLPENAEFALKEVARLKDLSGLEKFIRI
>NC_008312.1|WP_044137425.1|3665249_3666287_+|hypothetical-protein
MSEVPQFPEALAEALNNFPELNLDLPDPEDEEIPDSEFENVVDIAWKVCDRFDLQTEIWRGRILRIIRDREKKGGDGRGSGFLNWLKEREIGKSQAYALIELANSADTLMDKGHLDPDSINNFSKRAFVETAKSSTEVQQMVTDAAKKGDRITRREVKQLADEWTAVSSDLLPEEIRSKATSGSMPPRYLAPLVREMEKLPDSHLNAIQEEIVQSPELDTIKQLTSDARNLSKYLDAAAKVQALNESSLDMEMVLEEALRLECLNIVADLVKQSAQLETTMAKLYSSWRRLGNLSERLFVDTGASTPHLRHLLGCLDKLSSNVIELSLNDLNNQTVRLQILSETD
>NC_008312.1|WP_044137423.1|3663416_3664739_+|DUF697-domain-containing-protein
MTETNDINSPAANSEQSTQTTQDVKTKSKIDSWQSHVSGIWNDTNKRFMKLLPIGKARQTIMQWFTVDEAEVAKILVKVRAELPTTEAILIGKPQTGKSSIVRGLTGVSKEIIGQGFRPQTQHTQRYAYPSDDLPLLIFTDTVGLGDVKQETPIIIHELLAELQQESNRARILILTVKINDFATDTLRQVAQQLRQEYPNIPCLLAVTCLHEVYPHSTEDHPEYPPEYEELQRAFATIKEDFAELYNSSVLLDFTLEEDGYNPVFYGLEAFRDNLAQLLPEAEARTIHQLLDEQTSKQLGNIYRDVARRYILSFTIMAATAAAVPLPFATMPVLTALQVSMVGLLGNLYGQTISPSQAGGVVSAIGGGFLAQAVGRELIKFVPGLGSAIAASWVAAYTWALGESACVYFGDLMGGKKPDPQKIQGVMQEAFESAQERFKG
>NC_008312.1|WP_011611958.1|3660871_3662839_+|acetate--CoA-ligase
MSELTIESILQEKRLFQPPEKFVQTAQIKGIEQYKELYEKAKSNPEEFWAELAETELDWFQKWDKVLEWQPPFAKWFINGKINISYNCLDRHLTTWRRNKAALIWEGEPGDSRTITYAQLHREVCQMANVFKQLGVKKGDRVGIYMPMIPEAAIAMLACARIGAPHTVVFGGFSADALKNRLVDAEAKLVVTADGGWRKDAIVPLKEQVDKALMAGAPSVENVLVVKRTAQKIQMEPGRDHWWHDLQKSASGECPAEPMDSEDMLFILYTSGTTGTPKGVVHTTGGYNLYTHVTNKWAFDLQDTDVYWCTADVGWITGHSYIVYGPLSNGATTLMYEGAPRASNPGCLWDVVEKYGVTIFYTAPTAIRALMKMGEQHPNSRNLTSLRLLGTVGEPINPEAWIWYHRVIGDSKCPIVDTWWQTETGGFMITPLPGATPTKPGSATFPFPGIIADIVNEEGESVDGNNGGYLVVKHPWPGMMRTVYGDPDRFRRTYWEYLRPKNGEYIYFAGDGAHKDEDGYFWVMGRVDDVINVAGHRLGTMEVESALVSHPAVAEAAVVGKPDEVKGEDIVAFVSLEGGREPDENLEKELKQHVVKEIGAIARPGEIRFTDDLPKTRSGKIMRRLLRSLAAGQEITGDTSTLQDRSVLDKLRAGS
>NC_008312.1|WP_011611957.1|3659860_3660556_-|hypothetical-protein
MQAREIEPKLKQLSRLAWSTEPALAQRLDEVRRWIKDIRPGSLTQKRLLVGFLLELIKDGEFWLKLQSLTNEERQIFLQHLPSPITYWYESLFPKWFNKNDHKFYIWKQKLRSGEFNQKDAQLIESIARQIKSRDGFVVHRYIADLSMATDVIVSSNTGKPLCVQLTTISGEFCNYKYKEWKDTLQQWKIRRGIFVSYNPSQDRSVIQLVNLILHNSKHLKEAKYIKFCFR
>NC_008312.1|WP_011611956.1|3659572_3659785_-|hypothetical-protein
MVTTGTTLSNKERLEKAWQAFQAVQNLQEDRLTWGINHVSLYVENIDGDWLENWGEEDEEELTEKLLLRK
>NC_008312.1|WP_011611955.1|3657637_3658300_-|VWA-domain-containing-protein
MRLDELVEFAENPEPRCPCVLLLDTSASMTGTPIKALNDGLETFRDNLITDDLAKKRVEVAIISFDNQVKIVQDFITADQFENPILTAQGQTYMGTAIHKALDMIAARKSEYRNNGITYYRPWVFLITDGEPQGESEKVFKEAGDRIKQEEDNKHVAFFAVGVEGANMDKLGEIVQRTPLKLRGLNFREMFIWLSASMQQVSHSKVDEQVALPPPGWGAV
>NC_008312.1|WP_011611954.1|3656449_3657214_-|protein-phosphatase-2C-domain-containing-protein
MSIEAEIKWRVISVSVAGKSHEKRGQLCQDAHHWQILPEGILVAAVADGAGSSNLGDVGAKIAVGVAVEAISQQKLLPVDDVGWQFLLVDTLKAAKNAVLAESRVREVEGRELAATLILVVATPEFAIAAQVGDGAAVVGDGEENIFPVTSPQTGEHVNETTFLISEQGVENAQVNIWRGKLVHLAIFSDGLQMLALKMPMGLPHSPFFAPLFKFMTVVTNEEEANKQLEDFLRSPKVTGRTDDDLTLLLARYG
>NC_008312.1|WP_044136736.1|3656183_3656402_-|hypothetical-protein
MSEILLAPIEFELPELSRLKILWEYFLFEVVPRSQVINSQWLAQRSTELGGGDIWNLVRLTRSSGVSRISDI
>NC_008312.1|WP_011611953.1|3654023_3655592_-|lysine--tRNA-ligase
MAKSETRNEVEVRSQKVDELRAQGIDPYPSQAIERSHTTKQVIDLFSPPAKELEPGETDPNEKFLKVCGRITSKRDSGSIGFINLTDETGKIQLKIEKKLVKGDPGLSFKQVQKLLDVGDFVSAEGIGCRTNRGELSIQVNKLDVLSKAIIPFPDSYYGVNDPEICRRHREMDLAGNAEALQRFRVRSKIMQSIRTYLWDANFYEIETPILQSIYGGAAARPFVTHHNALDVDLYLRIATELFLKRAICGGFERVFELGRVFRNEGIDSTHNPEFTSLEVYQAYADYFEILGLVEDVICYSLTNILGDLKQIEYQGQTISLERQYDYSQKYPNFTGKHWQVKTMVEAVKDETGLDFDNLELPEAIRAAEKLNLKLSKLETQSLGYLLYAVFDQKVESTLIQPTFVIDFPVEVSPLAKRHHSKPGFVERFELFIHGTEYSNGFSELNDPQDQRQRFEEQIAQREAGDDEAHPMDEDFIQALSLGMPNCGGMGIGVDRLVMLLTNTQSIRDVIMFPTMRSTLKD
>NC_008312.1|WP_011611965.1|3672571_3675706_+|efflux-RND-transporter-permease-subunit
MSFHLSAWSIKKPVPTLVMFLVLTVVGLMSFFQLGIDNLPNIDIPLVSVTVTQQGAGPTELETQVTKKVEDAVAGLGDIEQLKSTVTDGLSTTVISFDLGVDSDRATNDVRNAIDKIRQDLPPDVNDPIITRIEIGGDGPIMTYAVASDKRSVEELSELVDKEISRAILNVPGVSQINRIGGADREILIELSPQRLESLGITATQVNDQIRALNANIPGGRSQTGGTEKNIRTLGSAETVEALKEYQIILPSGGAVPLSSVGKVIDGFEETRQTAWLLEKNSEGKALGSEQNLVRNNIGKPVVAFGVVRSTGSTLVTVEKNVRKTVAKLEKTLPEDVDLQLIFTLATDIEQSYQASIDALVIGSILTVIIVGIFLRDWRPTIVTAVALPLSILPTFLVMRALNYTLDGMTLLALALAMGNLVDDAICMIENIEQHINKGKNPFQAALDGSAEIGLAVVATTATIVAVFLPVAFMGGIPGKFFKPFGITVAVATMFSTLVATTMTPMLGARLLKHRRLKTSPGFPEHNYKQRKFRPYSQLLNWALRHKIITLAIAVIFFISSLQLIPLLPKGLTGAEDRGVSIVSLELSPGSTLAETEQATQQIMQLLQENQVVTSVFANVGSEFVNKSRLYVTILPRKERNFSQKEFEKQARPLFQNIPGARINFVSMGAGGTGKDLTIVLNSDNAVTLQQTSDALERQMREVPGLVDVTSSASLVKPEILIQPLPARAGDLGVSVQAIARTASLATIGDNEKNLAKFDLADRQIPIRVQLAEEFRNDLDVIKNLRIPSKNGRLVPLSAVAEISVGSGPAQIKRFNRYRQVSFGANLQGISLGDALTEVKSLPAINPLPLDISEQSDGSAKLMMDVFNGFASALGLSVLCIYAILVLLYNNFLYPIVILVALPLSIGGALLGLLIFQKELGLFALIGIVLLMGLVTKNAILLVDCSLANEEKGMARFHAVREAGISRLRPILMTTFSTMAGMLPIALELGAGGPVRSPMAIAVIGGLTVSTLLTLVVVPVLFSYVDLVAKNYENHIKVQSYSSK
>NC_008312.1|WP_011611966.1|3676130_3676451_+|hypothetical-protein
MSGYWRFQELRSSYSDWVELAMVRGDIAAHRFRKSSTVLQRKTSSECRWSSPEPGSKTFAPGTAASSTGTTFRRSASWWRDIERPKGSALRESVVQAKGPLNLENK
>NC_008312.1|WP_011611967.1|3676729_3678637_+|hypothetical-protein
MVKLKKWHLAILAIPPLAVVAFLMISAGRQINNWGINWVWGIFILIFVGWRRLLVKWTRPTVAQMEEVIAEVNKEIPAIDNTRNQPLENEATKQLEITLQEIIKSCRNDPPFWEDWQIFWQRCQEVVAAVAHAYYPEVKYPLLNIYIPQAYSLIRGTVDDIDRWIQKLSPTLNQITVGQAYQGYEIYRKLEPSARKLFQVLGWAQWLLNPVAAAAKVASRGYNERANQQLLANLSQILREVALRNLSQQAIAIYGGSKLEFLDSAISTQTLPKAETKTLEQILAQAQPTETVEQKPVNILLVGRTGAGKSSLINTLFAAERAEVDVLPSTDEIKNYQWQTQMGEILNLWDTPGYEQVNRADLRELVLDYAKTVDLLLLVNPALDPALQMDIDFLQDLKGEVANLPTIIIITQVDRLRPIREWQPPYDWIWGKNAKEKSIREATQYRAEILGDFCSQVLPVVTADIKNNRNGWNVDAISLSLLEAIAPAKQLRLAKFLCDRKARSVAAAQIINHYTFQMATTQGLTALLKSPVLQFISTLTTGSPALAYVLAEKIPVEDLPIVIGKLQMAYDLFSLLSEDTNLGSFDLLALWPLLLENPAAPDLNAWAFGHALVEYWMQDLSIIQLQQRFNNYLKI
>NC_008312.1|WP_011611968.1|3679357_3679600_-|hypothetical-protein
MSETLKANTSVPTTQEKEIEEVIKGLEQYRERIINETLEQAKKVKIPKAKAMANLEQHPELSKIDQALNELRSATQHQMR
>NC_008312.1|WP_044137430.1|3679707_3680367_+|HEAT-repeat-domain-containing-protein
MEIKQIQVYLKSSDSQERLKALTELRNYESEIVVPLLKTRQQDPEFLVRSFVAMGLGNKRTPEGFKILLEMMQNDPDYNVRAEAANSLSKFGAQAIPFLVEKFRQDNNWLMRRSILAPLIDMPFPEALYEVCMCAIADEDTTVQEVAISALGKLAGTKKETEALQKLLAFVSAESWNIRLRAAQGLGKFDVPQAKAALNYLSKDDNYKVVAAALESSLS
>NC_008312.1|WP_011611970.1|3680799_3685065_-|tetratricopeptide-repeat-protein
MSLPAVLHPDIVEFLRKEIGSNLQKRVWECIQTLKQQKFNSGLRVKKLKGINKRVWEARINSASRLIFTYDKSQRPETGKAQVYLAIQDICVDHDDVSRRAKARKNRPDAEWLETPEFEVILETNNFKNQDNNIDKNILYSSVEKANIEAMKALDLETNSDLTDDELLGNIQWRVLESETEWQKAIIEQNTDLPLKLTPEEYKLAKLSGNLLLSGSAGTGKTTVALYRMIQKRQYKNLGRRLYIAYNDLLVNNAEEQFYKIVTTNCQLELESKKSNNQVIFEFKNIQKLCLEILKKHQKIYYLQDEVNYQVFSEMYRAHPGKKQYPTNLIWEEIRGIIKGKQLAITEDILSEKEYEKITRNRVISMSNKNRREIYKIAEWYQKKLQKEKLYDEIDIVRQVLQLLKNNPRKKYDLIVCDEVQDLTEIQLELLFNLVAPSGNLFFAGDSYQMISPSGFRWETLKNKFYPHRQVYQQTLKFNFRSVGSLVNLANQLLKLRSRYLAKSVSNYSISNSISGQLARLISADYQTLIGILKETSLYPGDAILVRKESDKEKIRADLNSSFVFTIEEIKGLEFDTVFIVDFFQPQAKLWSKVIRGGILKEKEKPQLQLEFNLLYVGITRASRILNIWESRPSQLWQEPELRGLFQSIIPELVRSDCIETSPERWRQQGEYYLKSEFYQQAKECFNKSGDVILEKQAQGKFLIQKQAYYEAAEIFVELTEWQEAALLFEKVGKWQEAAKSWANIGEYKKQKICEASQLEANFKWSEAAQKWEEIPDFSNAKRCWMKVPQKKAEYRAMELEKKRQWLKAAIEYDRAKIPQKAAFCRAREFEKKKQWKEAMTQYQIAAMSEKVEKCRQEAVNVLHNQGLIKLQKRDHTGAIEDYNQAIFLEKNNYLLYHNRAIAIAQMGNLKGAIENFKKALELEPKDLQTYNNLGAAYVELGEFNEAIELFSQALKVDSQDSQIYQNLGVVRFKAGDKQGAIADYNQAIKLNPNKPEAYYNRGIAYRFLGHNQDAMNDFTKVLQLHPRVVDAYTQRGIVRFEVKDIEGAIADFNDAIKLNPKHPEAIYNRAIIRRLTKDNQGSLDDLNKVIQLHPKYIDAYIKRSIVRFDLGDHEGALKDLDSAVQLQPNNAEAYYQRANTKRSMGDILSAIADFENAIRLNPKYHQAYNDMGIVRLRRGDISGAMENFEAAIQINPNYAEGHNNRGFTKFRRGDIPGAMKDFEAAIQINPNYAEAYNNLGNSRFQTGDFQGAMRDFGETLRIHPKYVPAYNNRALALLKLGDFSGATTDCYQALKINPKYGLAYYNLGLIHTEMGDLEQAILDYNEVLRIYPRKIDAYVNRGLIYLKLKNYTQAIKDQTSALNINPNLPHVYSFRSEGYIQLGEFKAGIDDLHKAAEIYQQQGKLEERDKMMKRIEKIKE
>NC_008312.1|WP_044137434.1|3685332_3686040_+|5'/3'-nucleotidase-SurE
MTFILTNDDGINAPGIKALWEAINNADSAIPSFDKSIIVAPQGQFSGCGHQVTTNRPINVQRLSEDRYAIAGTPADCTRIAITHVNTNVKWVLSGINSGGNMGYDTYVSGTVAAVREAAFYKIPGIALSQYRQGKKPVNWERVTGLARSVLINLLKRPIEQGAFWNVNFPYLEPEAPDPEIVFCKTSIQPLPIAYQKDGEDFSYTGKYEERDRTPGTDVDVCLSGKIAVTKIKLS
>NC_008312.1|WP_052845780.1|3686720_3686966_-|hypothetical-protein
MSPGTGNNKKNTISRQKVDWYISCSYEFYGRTTSKKTDVVGVCLGVKTLATLSDGEVLESVKYDRRFETKLSRMQGLTIKK
>NC_008312.1|WP_155994397.1|3686925_3687192_-|hypothetical-protein
MKKLSSRVHQYVFIHLAEAFKRFFAFGMLRKQGLGKYPRFKKKGKYDSWTIDNCGKPIELNGWSHKLPFIGIVKTYEPWHRQQQKKHY
>NC_008312.1|WP_044136738.1|3687914_3688112_+|hypothetical-protein
MYQYILSTSIFISPVLIGLNAIPETTSNFTHIPQLKSAGQSPIQLAAHKLEQEDVTAGTSRDTRD

Crispr_ID: NC_008312_30

• CRISPR_ID: NC_008312_30
• CRISPR_location: 4031033-4031148
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NC_008312_30

Consensus_repeat	Method
AAAAAAATTAACTATTGGATACCTCAAAAAAAC	CRISPRCasFinder

spacers of NC_008312_30

>30.1|4031066|50|NC_008312|CRISPRCasFinder
GGAATTTAGAAAAATATAAATTCTGAAAAATTTAGTATTAAACTGATATG

CRISPR arrays and Neighbor proteins around NC_008312_30

CRISPR arrays

The CRISPR arrays of NC_008312_30

>merge|NC_008312|30|4031033-4031148|CRISPRCasFinder
AAAAAAATTAACTATTGGATACCTCAAAAAAACGGAATTTAGAAAAATATAAATTCTGAAAAATTTAGTATTAAACTGATATGAAAAAAATTAACTACTGGATACCTCAAAAAAAC

>NC_008312|30|25|4031033-4031148|CRISPRCasFinder
AAAAAAATTAACTATTGGATACCTCAAAAAAAC	GGAATTTAGAAAAATATAAATTCTGAAAAATTTAGTATTAAACTGATATG
AAAAAAATTAACTACTGGATACCTCAAAAAAAC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_008312.1|WP_011612158.1|4018527_4019160_-|2OG-Fe(II)-oxygenase	unknown	unknown	gnl|CDD|379309
NC_008312.1|WP_155994690.1|4022247_4023477_-|LytR-family-transcriptional-regulator	unknown	unknown	gnl|CDD|224235
NC_008312.1|WP_011612175.1|4043561_4045433_+|hypothetical-protein	unknown	unknown	gnl|CDD|319862
NC_008312.1|WP_011612165.1|4026712_4028083_-|PDZ-domain-containing-protein	unknown	unknown	gnl|CDD|377640
NC_008312.1|WP_155994414.1|4039901_4040987_+|hypothetical-protein	unknown	unknown	unknown
NC_008312.1|WP_011612163.1|4024834_4025545_+|ribulose-phosphate-3-epimerase	unknown	unknown	gnl|CDD|235515
NC_008312.1|WP_011612160.1|4020220_4020817_-|sulfite-oxidase-like-oxidoreductase	unknown	unknown	gnl|CDD|239027
NC_008312.1|WP_044136779.1|4035390_4036191_+|HAD-family-hydrolase	unknown	unknown	gnl|CDD|366257
NC_008312.1|WP_155994412.1|4037877_4038027_-|hypothetical-protein	unknown	unknown	unknown
NC_008312.1|WP_011612164.1|4025709_4026459_-|DsbA-family-protein	unknown	unknown	gnl|CDD|224565
NC_008312.1|WP_011612166.1|4028144_4029392_-|protein-kinase	unknown	unknown	gnl|CDD|270916
NC_008312.1|WP_011612167.1|4029616_4030210_+|FHA-domain-containing-protein	unknown	unknown	gnl|CDD|238017
NC_008312.1|WP_011612174.1|4041421_4043224_+|GUN4-like	unknown	unknown	gnl|CDD|319862
NC_008312.1|WP_011612159.1|4019273_4019906_-|2OG-Fe(II)-oxygenase	unknown	unknown	gnl|CDD|379309
NC_008312.1|WP_011612168.1|4031580_4033479_+|FHA-domain-containing-protein	unknown	unknown	gnl|CDD|238017
NC_008312.1|WP_011612169.1|4034053_4034458_+|hypothetical-protein	unknown	unknown	unknown
NC_008312.1|WP_044136778.1|4023774_4024146_-|hypothetical-protein	unknown	unknown	unknown
NC_008312.1|WP_011612170.1|4034599_4035040_-|hypothetical-protein	unknown	unknown	unknown
NC_008312.1|WP_155994413.1|4038176_4038326_-|hypothetical-protein	unknown	unknown	unknown
NC_008312.1|WP_011612172.1|4036499_4037714_+|nuclease	unknown	unknown	gnl|CDD|214920

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_008312.1|WP_011612158.1|4018527_4019160_-|2OG-Fe(II)-oxygenase	gnl|CDD|379309	pfam13640, 2OG-FeII_Oxy_3, 2OG-Fe(II) oxygenase superfamily. This family contains members of the 2-oxoglutarate (2OG) and Fe(II)-dependent oxygenase superfamily.	1.18511e-16
NC_008312.1|WP_155994690.1|4022247_4023477_-|LytR-family-transcriptional-regulator	gnl|CDD|224235	COG1316, LytR, Transcriptional regulator [Transcription].	1.27372e-62
NC_008312.1|WP_011612175.1|4043561_4045433_+|hypothetical-protein	gnl|CDD|319862	cd16383, GUN4, porphyrin-binding protein domain GUN4. GUN4 is a porphyrin-binding protein involved in chlorophyll biosynthesis regulation and intracellular signaling, found in aerobic photosynthetic organisms. It has been implicated in retrograde signalling between the chloroplast and nucleus. GUN4 can bind protoporphyrin IX (PIX) and magnesium protoporphyrin IX (MgPIX), substrate and product of the Mg-chelatase, as well as heme and cobalt protoporphyrin IX (CoPIX). It may play a role in protecting plants from reactive oxygen species (ROS)-mediated damage.	2.66776e-68
NC_008312.1|WP_011612165.1|4026712_4028083_-|PDZ-domain-containing-protein	gnl|CDD|377640	pfam06271, RDD, RDD family. This family of proteins contain three highly conserved amino acids: one arginine and two aspartates, hence the name of RDD family. This region contains two predicted transmembrane regions. The arginine occurs at the N-terminus of the first helix and the first aspartate occurs in the middle of this helix. The molecular function of this region is unknown. However this region may be involved in transport of an as yet unknown set of ligands (Bateman A pers. obs.).	1.36555e-15
NC_008312.1|WP_011612163.1|4024834_4025545_+|ribulose-phosphate-3-epimerase	gnl|CDD|235515	PRK05581, PRK05581, ribulose-phosphate 3-epimerase; Validated.	4.40912e-145
NC_008312.1|WP_011612160.1|4020220_4020817_-|sulfite-oxidase-like-oxidoreductase	gnl|CDD|239027	cd02109, arch_bact_SO_family_Moco, bacterial and archael members of the sulfite oxidase (SO) family of molybdopterin binding domains. This molybdopterin cofactor (Moco) binding domain is found in a variety of oxidoreductases, main members of this family are nitrate reductase (NR) and sulfite oxidase (SO). Common features of all known members of this family are that they contain one single pterin cofactor and part of the coordination of the metal (Mo) is a cysteine ligand of the protein and that they catalyze the transfer of an oxygen to or from a lone pair of electrons on the substrate. The specific function of this subgroup is unknown.	1.61777e-96
NC_008312.1|WP_044136779.1|4035390_4036191_+|HAD-family-hydrolase	gnl|CDD|366257	pfam00702, Hydrolase, haloacid dehalogenase-like hydrolase. This family is structurally different from the alpha/beta hydrolase family (pfam00561). This family includes L-2-haloacid dehalogenase, epoxide hydrolases and phosphatases. The structure of the family consists of two domains. One is an inserted four helix bundle, which is the least well conserved region of the alignment, between residues 16 and 96 of Pseudomonas sp. (S)-2-haloacid dehalogenase 1. The rest of the fold is composed of the core alpha/beta domain. Those members with the characteristic DxD triad at the N-terminus are probably phosphatidylglycerolphosphate (PGP) phosphatases involved in cardiolipin biosynthesis in the mitochondria.	0.000464764
NC_008312.1|WP_011612164.1|4025709_4026459_-|DsbA-family-protein	gnl|CDD|224565	COG1651, DsbG, Protein-disulfide isomerase [Posttranslational modification, protein turnover, chaperones].	5.74944e-33
NC_008312.1|WP_011612166.1|4028144_4029392_-|protein-kinase	gnl|CDD|270916	cd14014, STKc_PknB_like, Catalytic domain of bacterial Serine/Threonine kinases, PknB and similar proteins. STKs catalyze the transfer of the gamma-phosphoryl group from ATP to serine/threonine residues on protein substrates. This subfamily includes many bacterial eukaryotic-type STKs including Staphylococcus aureus PknB (also called PrkC or Stk1), Bacillus subtilis PrkC, and Mycobacterium tuberculosis Pkn proteins (PknB, PknD, PknE, PknF, PknL, and PknH), among others. S. aureus PknB is the only eukaryotic-type STK present in this species, although many microorganisms encode for several such proteins. It is important for the survival and pathogenesis of S. aureus as it is involved in the regulation of purine and pyrimidine biosynthesis, cell wall metabolism, autolysis, virulence, and antibiotic resistance. M. tuberculosis PknB is essential for growth and it acts on diverse substrates including proteins involved in peptidoglycan synthesis, cell division, transcription, stress responses, and metabolic regulation. B. subtilis PrkC is located at the inner membrane of endospores and functions to trigger spore germination. Bacterial STKs in this subfamily show varied domain architectures. The well-characterized members such as S. aureus and M. tuberculosis PknB, and B. subtilis PrkC, contain an N-terminal cytosolic kinase domain, a transmembrane (TM) segment, and mutliple C-terminal extracellular PASTA domains. The PknB subfamily is part of a larger superfamily that includes the catalytic domains of other protein STKs, protein tyrosine kinases, RIO kinases, aminoglycoside phosphotransferase, choline kinase, and phosphoinositide 3-kinase.	1.08528e-62
NC_008312.1|WP_011612167.1|4029616_4030210_+|FHA-domain-containing-protein	gnl|CDD|238017	cd00060, FHA, Forkhead associated domain (FHA); found in eukaryotic and prokaryotic proteins. Putative nuclear signalling domain. FHA domains may bind phosphothreonine, phosphoserine and sometimes phosphotyrosine. In eukaryotes, many FHA domain-containing proteins localize to the nucleus, where they participate in establishing or maintaining cell cycle checkpoints, DNA repair, or transcriptional regulation. Members of the FHA family include: Dun1, Rad53, Cds1, Mek1, KAPP(kinase-associated protein phosphatase),and Ki-67 (a human nuclear protein related to cell proliferation).	3.0647e-17
NC_008312.1|WP_011612174.1|4041421_4043224_+|GUN4-like	gnl|CDD|319862	cd16383, GUN4, porphyrin-binding protein domain GUN4. GUN4 is a porphyrin-binding protein involved in chlorophyll biosynthesis regulation and intracellular signaling, found in aerobic photosynthetic organisms. It has been implicated in retrograde signalling between the chloroplast and nucleus. GUN4 can bind protoporphyrin IX (PIX) and magnesium protoporphyrin IX (MgPIX), substrate and product of the Mg-chelatase, as well as heme and cobalt protoporphyrin IX (CoPIX). It may play a role in protecting plants from reactive oxygen species (ROS)-mediated damage.	9.04549e-67
NC_008312.1|WP_011612159.1|4019273_4019906_-|2OG-Fe(II)-oxygenase	gnl|CDD|379309	pfam13640, 2OG-FeII_Oxy_3, 2OG-Fe(II) oxygenase superfamily. This family contains members of the 2-oxoglutarate (2OG) and Fe(II)-dependent oxygenase superfamily.	3.32696e-13
NC_008312.1|WP_011612168.1|4031580_4033479_+|FHA-domain-containing-protein	gnl|CDD|238017	cd00060, FHA, Forkhead associated domain (FHA); found in eukaryotic and prokaryotic proteins. Putative nuclear signalling domain. FHA domains may bind phosphothreonine, phosphoserine and sometimes phosphotyrosine. In eukaryotes, many FHA domain-containing proteins localize to the nucleus, where they participate in establishing or maintaining cell cycle checkpoints, DNA repair, or transcriptional regulation. Members of the FHA family include: Dun1, Rad53, Cds1, Mek1, KAPP(kinase-associated protein phosphatase),and Ki-67 (a human nuclear protein related to cell proliferation).	4.7566e-11
NC_008312.1|WP_011612172.1|4036499_4037714_+|nuclease	gnl|CDD|214920	smart00933, NurA, NurA nuclease. This family includes NurA a nuclease exhibiting both single-stranded endonuclease activity and 5'-3' exonuclease activity on single-stranded and double-stranded DNA from the hyperthermophilic archaeon Sulfolobus acidocaldarius.	4.65233e-52

Protein sequences

>NC_008312.1|WP_011612167.1|4029616_4030210_+|FHA-domain-containing-protein
MNEIIISWEEQDTTKTKTIKEIQPSKNPGTVRLGREPANCDITFDDPSVSRLHVEIFYNSQDNKFYLRNLKASNPPIVDKKLIVKYAEVVLNNNSLICLGQTKIKVIYNANNIFTSPTILQSPIPLNNNSTVLSPPDASQLKELATKPKRSIFGANYLVCPNPNCGKLVSIEKLNIGCSWCGTSLADAKSIIVPNNN
>NC_008312.1|WP_011612166.1|4028144_4029392_-|protein-kinase
MFLKKGQYEIIKTLTAGSFGQTYIAINKHSQPPNQEVVIKKLKPQQNDPYTLQNAERLFKKEVESLKKLGYHKQIPTYIDNFEENNEFYLVQEYIKGKDLTEELKPGNKLSESEVIHLLIDILEVLDFVHKNGVIHRDIKPSNLMRRTEDNQIVLIDFGAVKEVGTVLVNQQGQKTITVIIGTPGYMAGEQGQGHPECASDVYAVGKIAIQALMGVSPNLLAPNLLLRNQNNPELLWRQGVLISQELGNIIDKMVEQNCLLRYHNAGEALQEIKGILPADVEKYAGFWMRLAADLIDKTIIIIGSIIVDFIINDVTVDEAEFMARILVFYIIAGFIYCPVMDSSKTQGTFGKMLMGIKVTDLQRRRIYFDKATKRHSSKFFSYLTLGIGFILASFNKIKRVLHDIIYGCLVIKNI
>NC_008312.1|WP_011612165.1|4026712_4028083_-|PDZ-domain-containing-protein
MVFLLLIYLTLGKQEINENTSVKSSIFLVLNTVLGWLYFAILESSQIQGTLGKQIVGISVTDLRGNKISFGKATARYFGKSFFLVVWIAATIVAIMGEGTGSTDSPYLILAGILFILGLIVLVVGYLMAAFTPEKQALHDIMARCLVERASGQPRAIPWKSLVALAIAGFFSSKILAMIPEAPNDPNNDTISEPTPTETSPPTRPRTKYPKVSTKENRIFGPLIEPDDRLKEAFKGVWKLSYSVGFVVHESQLSMTGPSGVMFTQFFDSDINQTKTILQKIELLSSAKGLVLLGSDPTNLDSGEIDSAYSADNFRVAQRPDGTFEFRNYSLSDDGSIFESPVEAEFSGYPKLGVQMAELTREVKQKLNTEIGSNVITEEQGVLVIKVFDDSPAEKANIRPGDVLQEVKNRTVTSPSQVQEIVQSSYLFLPIDIQLNRSGENINLSVQPECCMTQEE
>NC_008312.1|WP_011612164.1|4025709_4026459_-|DsbA-family-protein
MRVLFLLSIVMTTCISLSGCTFSDKLTNNPIKPELEQQVLQIIRDHPEVIIESVQAYQQEQQQEKEASQQKTLQQFKNNPQEQIGESPTFGSTAQKIVLFEFSDFQCPFCAKAQENLKEFMDKHQDRVTLVFKHLPLTNIHPQANPAAKAAWAAQQQGKFWEYHDALFEQQDRLGEELYLEVANNLGLNIDKFNSDRQSEAASISIETDIQLAKKIGVSGTPFFVMNGETFSGAVKLSQIEETFAKVSQ
>NC_008312.1|WP_011612163.1|4024834_4025545_+|ribulose-phosphate-3-epimerase
MTTTEKKPIVISPSILSADFSRLGDEVRAVDQAGADWIHIDVMDGRFVPNITIGPLIVKALRPVTKKPLDVHLMIVEPEKYVEDFAKAGADIISVHAEHNASPHLHRTLGQIKELGKQAGVVLNPSTPLELIEYVLDLCDLVLIMSVNPGFGGQSFIPTVISKIRKLREMCDARGLNPWIEVDGGLKTDNTWQVLEAGANAIVAGSAVFKANDYAEAINGIRNSKRPVPQPQLATV
>NC_008312.1|WP_044136778.1|4023774_4024146_-|hypothetical-protein
MKNTAQFENPYINRQELFLLVTPILGFFPAIWILFRQKASIQHRAVSRLIVTLTLIWLLGNICLQLGVEIGESGIITLLLINSLLTTSYFIISFGLMVRIWKRQPLWLPGINRIAEKVVGKHL
>NC_008312.1|WP_155994690.1|4022247_4023477_-|LytR-family-transcriptional-regulator
MQQRLSPEDAAVFSQKNLAKSNMRLPELTRPVNILLLGIKVLTSDLKEYPQDDDLGYHALVNSFKGLSDTILMVRFDPKNQKLTLLSIPRDTRTYVEDRGLTKINAANYYGGPAKSAKAVSELLGGIGIDRYIRVNVQGVEKLIDALGGLKVHVPLDMKYQDDSQHLYINLKAGEQHLNGNQVLQFLRFRYDNLGDIGRVQRQQLLMRAFMEQSVNMKTLSRLPKILSVIQSHIDTNLSVEELVALMNFAAKIKRPNVQMLMVPGEFSDPKKYKSSYWLPDLTTLDNMMSKHFDFGYQAWEVENLDYNYITVAVQGSTDNLEAVDELVMSLKETGYWHVKVAKPWSKSLEVTRIIAQKGDLQAAQAVQRSLGFGEVFVESTGSLRSDVTIQLGEDVLSIKDKSQNLQNW
>NC_008312.1|WP_011612160.1|4020220_4020817_-|sulfite-oxidase-like-oxidoreductase
MLGKFFRKPEAELSDRVPPGQHLAKGFPVLTYGETPNISQDKWQLKVWGLAKPITFNWLDLMAMPQNHFKADFHCVTRWSKLDVQWTGVKVIDLMAHVELDPKAIHIMEHCYGGYTTNISLSDFLREENFFAHTLFDEPLPYNHGGPVRLVVPHLYAWKSAKWINGLEFLDNEELGFWERNGYHKRGEPWSEERYGSI
>NC_008312.1|WP_011612159.1|4019273_4019906_-|2OG-Fe(II)-oxygenase
MFWMYPEKKYNQTVFTCYDASEPSHFCQRGENWGVFTADECDWIISLSQNVATSQNYIAEVTNPSYRQVSAWEIYQTQETNWVWQRLINNVISGNNHCWNYDIVGILESIQLICYDSTNTSEKIQDNCDLHIDNEYPLSFRKISFSVELSEPNSYEGAELNLYVQKNQKILPRSRGSMIMFPSFILHEVTPIISGKRWALIGWVGGPQFR
>NC_008312.1|WP_011612158.1|4018527_4019160_-|2OG-Fe(II)-oxygenase
MVWIYPQQKYRQIKYAYYDASQKEHFCQPGENWGAFTAQECERVISLSKEMKLSKGIVDGKIKPEIRQVNVWGLSYSESTRWLWEKLINSVKYANNKWWNYDIYGIMDSMQLLCYEASKNQESIQDHYNKHIDVGEAYYYRKISISIQLSDPQDYEGSELKLYTRREAENLPKARGTMILFPSFVLHEVTPIIKGKRWALVCWVCGPQFR
>NC_008312.1|WP_011612168.1|4031580_4033479_+|FHA-domain-containing-protein
MTSENFSIQLIWTDLTTGYLRQPQYKLPVTIGRKFSKMPSTIGEDSVSRLELKHTEISGYHALINLEKGNLVIVDQNSTNGIFINGLRQTKSLIKDGDVLQLGPYKIDIRINFPPPWFVDAEKVKVSDLRKSGYTLDEADYGTIGGGLGSFIWVDFLRIFGVKSNQIVALGIVPLDENGNIPPNETQKSYWHYKQLCLNSQIPDHERLRSNSDSCPDNIWGWPSYALREAWQDFSHGRILSSLKCLWQVFAEPTFAQTYTPKARNVFASIDREAKRIGWDQIFRFGRVRAIRKTDDGRYAIAYSFSSSKSRDYGFLIVSFLHLATGYPKLKFLEDLQMYRRQTEDFRAVVNAYEDHAHVYEHLEKNGGVVLIRGRGIVASRIIQRIYEVRQRSQKNIGIIHLMRSEVTKGKKFGVAQRQVENNFEFQPFNWPKACWGGELRVKLEQAKPEKRKDLLKEWGGTTTASRSDWRQIIQQAKLDKWYKVEFGKVTRVEPNQGNGIITHISTEFPKLALVTDFIIDATGLEANVDESPLIYDLVKKYNLQLNAQKRLTVSNDFEVIGVSNEPGKIYACGAITFGGPYAAVDSFLGLQYTALRCVDHLFKIQAPGIKYLNGFSSIGQWWKWATNQSPS
>NC_008312.1|WP_011612169.1|4034053_4034458_+|hypothetical-protein
MTPTLFGRWQTRLLLLATVGILITIPFGELIYFLVLGYIAVLGLFWDILYDLLQKFRWDRDWPGIYQLLAAIWEAIFLLFIAKTIDLPLLEMSDFKIKNFALHYSLVWLGLYIVSQTVMRIYFPRWRFRGGRWL
>NC_008312.1|WP_011612170.1|4034599_4035040_-|hypothetical-protein
MTETNPTSDTSNQPSIQSSLPTKLEQGSQQRTTLQVETKPVETKEIQEETTKLALPGNRPIGKTNLKYSKTISNRPIVSNSLKINHTMSASGIRPVVDSGLEFNNTITASGVRPIGTNNLEVSKILMNRPVASNGVNSEDLMGFLD
>NC_008312.1|WP_044136779.1|4035390_4036191_+|HAD-family-hydrolase
MAIKTPTVLALDFDGVLCNGLSEYFQTAWRTYSQFWQISDEIPLNDLMEKFYRLRPVIEIGWEMPLLIRALILGIEEDTIFQEWQAIAEKIVIQENLDPWKIGACLDNTRDEWIVKDLEGWLSLHQFYPGVVEKLKELMVSEVKPIIITTKEGRFARSLLHKVGVNLPEADIIGKESKRPKYETLKILLAKLGARTTIWFIEDRLKTLLSIQKHPDLQEVELFLADWGYNTQKERNSVAQYPSIHLLSSAQFCQDFSKWKFGGKKE
>NC_008312.1|WP_011612172.1|4036499_4037714_+|nuclease
MLDLTKLAQQMQGMSQHLTKEAMAAKNRLEIAQQLLEAAKDEQEDLLALEESWCDRILFNPAIPIESLDTYPLINPPPKSHTVFATDGSQIAPSQHEIAYCYLLNIGRVMLHYGESRYPLLDSIPEIFYEPGDLYISRQWGIKTEEWMGYRRTISEALVLAQLGCEWVKNNSDNLGSPILAMVDGSLIYWFLESLPSEARDRILNPIMEAWNKLKLAGIPLVGYLSASRSNESLSFLRLKACIYDEPDCISNCPNVGLGGFGFTEKAPCQSFEPLRDVIFWGSILRPGQRSPLWQSSARILHLYGDNTIYFCYVNVGREVARIDMPEWVVENEEMLELVLGMILAQVQKGYGYPVALAEAHNQAVVRGGDRISFFALLEQEMIKAGLKNVGTSYKETRKRSSIA
>NC_008312.1|WP_155994412.1|4037877_4038027_-|hypothetical-protein
MSTTDVRIAARDSNFTEFHLQPSPFLIELSEARVLKKNSESTFYYTSIS
>NC_008312.1|WP_155994413.1|4038176_4038326_-|hypothetical-protein
MSTTDVRIAARDSNFTEFHLQPSPFLIGLSEARVLKKNSESTFYYTSIS
>NC_008312.1|WP_155994414.1|4039901_4040987_+|hypothetical-protein
MTLALGELLRKMKYLIRVFGLTFLSLTLTNCSLCPKKIVSLLEPSILRLFYTNKPLISGETEAYNLLTPAHVVKKEGKNLLENNDGKVANVTKLEIFPSNINLALATFEQTGKKCNCNDPLLRIGNSNSFKTSSSVYTLGFALWGRQLLSEFAFGSVYTEERRRPGDGVYDQALSVSGNTEVPVMDQRVKFMAAHRKSDQEQEMVESLASRPPKLSESECQNFLEAVFLEGNIQGLTFSWGIPITLNFFREYSSKAIAVEIQEQEVELPEPLEEHRWKEEEEERGEIEPEGQKQLHKAEYKARQEELVEIQSLQLQKELMSEKQKKRATIGIGSFWVDFLIFGVGLNALVLYGVFSYTKKG
>NC_008312.1|WP_011612174.1|4041421_4043224_+|GUN4-like
MKSLLPIISITFLSITLTNFSSSVKKTEVEDIASRLEDSIVKLSYKNQPGDGTGFFVEVEGKSEVCSVLTAAHVVEKEGQKILWTEKDEKVWDVATVERFPGSIDLALITFKPHTKRCNYPALKIGKPENLKIGSSIFVYGFPRLDQHLVAQFVGGQVSALKKKARGYGVAYKALTVEGMSGAPVVDTKGEVVAVHGSSNSKMVPSLISQQISRPDIEWQLDRQTFNRINNSSLTCAWGVPINYFRESKFYNAKLYSNLLPLDLNKWILSIFSISGLMFSSGIVSFRFKRFQASPVSGQEQNEQEREFEDVVFRGEEEHRPLSSPANIPTQLQNEQEREFEDVVFRGEEERRPLSSPANIQTQLQNEQEREFEDVVFRGEEEYRPLSSLANIPTQLQNEQEREFEDVVFRGEEEHRPLSSLANIQTQEQQRQGGVQVLEPPSSVVSVPLVSAAGVDYTRLHELLVAKRWKEADDETYQRMIEVADRKSQGWLRIEDTKNFPSQDLGIIDKLWLRYSNGMFGFSVQKQVYQSLGGTQRYNPKVVEDFGDKVGWRLEGKWLSYDGLTVSDNYYRGHLPCCGNEGSLYGWAAVLWSLLSHKDL
>NC_008312.1|WP_011612175.1|4043561_4045433_+|hypothetical-protein
MKSLFSILGLTFLSVILTNCSLSPEKIASRLKPSIVKLSYKNKPGHGTGFFVPGELGVCTVLTAAHVVDEEGKVRLRTEKDGKFWDAATVKIFPRTIDMALVTFKPETEKCNYRALKIGNSDSLRIGSSIFIYGFPRRGGALVPQFVDGKVSALDRLARGYGVSYSTLTVGGMSGAPVVDGRGRVVAVHGMSDVEIVQSLASQQAGLSEDERLLSQQAQESLRAAGVQRLTFSWGIPITFFRESKFYYSQVSGLSLWMLFYGGAVFGGGVVYFGLRYFQAPRVSGERQGDWERQLKNEKRRREEVEGRLSSLESSRAQARQELERQIEWERGKRREFEALLKNEKRGREEVEGRLSSLESSGAQAQQELERQLEWERGKRREFEALLKNEKRGREEVEGRLSSLESSGAQARQELERQLEWERGKRQELEALLQSQGEVQPRVVEPLSSGDVPLVSAVGVSYSRLRDLLVAKKWREADQETYKRMLEVAGRESEGWFRGSDIENFPCQDLATIDKLWVKYSSGKFGFSVQKQIYQSLGGTNEWDEKVWTAFSDQVGWRKRGRWLNYDEIFDETSHCVGLLPGITHCDLGLTGGPGPFDLIDSLRILKMVAIIFAITIFSRRDL

Crispr_ID: NC_008312_31

• CRISPR_ID: NC_008312_31
• CRISPR_location: 4129226-4129391
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NC_008312_31

Consensus_repeat	Method
AAGTTTTGAGTAGACTAATAGATTGATTTTATGAATAGCTTCGTAAGTTAAAT	CRISPRCasFinder

spacers of NC_008312_31

>31.1|4129279|60|NC_008312|CRISPRCasFinder
TATCTTGCTTGATTGTTAAACTGAATAATCTATGTGATTCGCCGTAACCCAACGAAATGT

CRISPR arrays and Neighbor proteins around NC_008312_31

CRISPR arrays

The CRISPR arrays of NC_008312_31

>merge|NC_008312|31|4129226-4129391|CRISPRCasFinder
AAGTTTTGAGTAGACTAATAGATTGATTTTATGAATAGCTTCGTAAGTTAAATTATCTTGCTTGATTGTTAAACTGAATAATCTATGTGATTCGCCGTAACCCAACGAAATGTAAGTTTTGAGTAGACTAATAGATTGATTTTATGAATAGCTTAGTAAGTTAAAT

>NC_008312|31|26|4129226-4129391|CRISPRCasFinder
AAGTTTTGAGTAGACTAATAGATTGATTTTATGAATAGCTTCGTAAGTTAAAT	TATCTTGCTTGATTGTTAAACTGAATAATCTATGTGATTCGCCGTAACCCAACGAAATGT
AAGTTTTGAGTAGACTAATAGATTGATTTTATGAATAGCTTAGTAAGTTAAAT

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_008312.1|WP_044137494.1|4123683_4124745_+|undecaprenyl/decaprenyl-phosphate-alpha-N-acetylglucosaminyl-1-phosphate-transferase	unknown	unknown	gnl|CDD|133463
NC_008312.1|WP_011612225.1|4138434_4140921_-|tetratricopeptide-repeat-protein	unknown	unknown	gnl|CDD|378942
NC_008312.1|WP_011612213.1|4118495_4119104_+|nitroreductase-family-protein	unknown	unknown	gnl|CDD|380314
NC_008312.1|WP_011612212.1|4114447_4116106_+|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl|CDD|224048
NC_008312.1|WP_011612208.1|4108472_4109852_-|aldehyde-dehydrogenase	unknown	unknown	gnl|CDD|143454
NC_008312.1|WP_011612210.1|4113225_4113612_+|heterocyst-frequency-control-protein-PatD	unknown	unknown	unknown
NC_008312.1|WP_011612224.1|4135836_4136874_+|NADP-dependent-oxidoreductase	unknown	unknown	gnl|CDD|381320
NC_008312.1|WP_011612220.1|4129511_4130651_+|ADP-ribosylglycohydrolase-family-protein	unknown	unknown	gnl|CDD|377122
NC_008312.1|WP_011612215.1|4122021_4123299_+|serine-hydroxymethyltransferase	unknown	unknown	gnl|CDD|234571
NC_008312.1|WP_044137498.1|4143819_4144842_-|sulfotransferase	unknown	unknown	gnl|CDD|379204
NC_008312.1|WP_155994691.1|4142264_4143506_-|chromate-efflux-transporter	unknown	unknown	gnl|CDD|273350
NC_008312.1|WP_011612209.1|4110198_4112451_-|bifunctional-(p)ppGpp-synthetase/guanosine-3',5'-bis(diphosphate)-3'-pyrophosphohydrolase	unknown	unknown	gnl|CDD|223394
NC_008312.1|WP_011612217.1|4126185_4127463_+|competence/damage-inducible-protein-A	unknown	unknown	gnl|CDD|234789
NC_008312.1|WP_011612229.1|4144887_4145262_-|hypothetical-protein	unknown	unknown	unknown
NC_008312.1|WP_011612226.1|4141096_4141306_-|hypothetical-protein	unknown	unknown	unknown
NC_008312.1|WP_011612211.1|4113608_4114220_+|zf-TFIIB-domain-containing-protein	unknown	unknown	gnl|CDD|379195
NC_008312.1|WP_011612222.1|4133384_4134116_-|JAB-domain-containing-protein	unknown	unknown	gnl|CDD|178801
NC_008312.1|WP_011612223.1|4134326_4134872_+|acireductone-dioxygenase	unknown	unknown	gnl|CDD|380360
NC_008312.1|WP_011612221.1|4130681_4133192_+|HDIG-domain-containing-protein	unknown	unknown	gnl|CDD|224397
NC_008312.1|WP_044136786.1|4127923_4128370_+|type-II-3-dehydroquinate-dehydratase	unknown	unknown	gnl|CDD|235443

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_008312.1|WP_044137494.1|4123683_4124745_+|undecaprenyl/decaprenyl-phosphate-alpha-N-acetylglucosaminyl-1-phosphate-transferase	gnl|CDD|133463	cd06853, GT_WecA_like, This subfamily contains Escherichia coli WecA, Bacillus subtilis TagO and related proteins. WecA is an UDP-N-acetylglucosamine (GlcNAc):undecaprenyl-phosphate (Und-P) GlcNAc-1-phosphate transferase that catalyzes the formation of a phosphodiester bond between a membrane-associated undecaprenyl-phosphate molecule and N-acetylglucosamine 1-phosphate, which is usually donated by a soluble UDP-N-acetylglucosamine precursor. WecA participates in the biosynthesis of O antigen LPS in many enteric bacteria and is also involved in the biosynthesis of enterobacterial common antigen. A conserved short sequence motif and a conserved arginine at a cytosolic loop of this integral membrane protein were shown to be critical in recognition of substrate UDP-N-acetylglucosamine.	2.03867e-87
NC_008312.1|WP_011612225.1|4138434_4140921_-|tetratricopeptide-repeat-protein	gnl|CDD|378942	pfam12770, CHAT, CHAT domain. These proteins appear to be related to peptidases in peptidase clan CD that includes the caspases. This domain has been termed the CHAT domain for Caspase HetF Associated with Tprs. This family has been identified as a sister group to the separins.	2.41654e-62
NC_008312.1|WP_011612213.1|4118495_4119104_+|nitroreductase-family-protein	gnl|CDD|380314	cd02137, MhqN-like, nitroreductase family protein similar to the NAD(P)H nitroreductase MhqN. A diverse subfamily of the nitroreductase family containing uncharacterized proteins; includes nitroreductases MhqN, YodC, YdgI, DrgA. Nitroreductase catalyzes the reduction of nitroaromatic compounds such as nitrotoluenes, nitrofurans and nitroimidazoles. This process requires NAD(P)H as electron donor in an obligatory two-electron transfer and uses FMN as cofactor. The enzyme is typically a homodimer.	5.18379e-64
NC_008312.1|WP_011612212.1|4114447_4116106_+|ABC-transporter-ATP-binding-protein	gnl|CDD|224048	COG1123, COG1123, ATPase components of various ABC-type transport systems, contain duplicated ATPase [General function prediction only].	0
NC_008312.1|WP_011612208.1|4108472_4109852_-|aldehyde-dehydrogenase	gnl|CDD|143454	cd07136, ALDH_YwdH-P39616, Bacillus subtilis aldehyde dehydrogenase ywdH-like. Uncharacterized Bacillus subtilis ywdH aldehyde dehydrogenase (locus P39616) most closely related to the ALDHs and fatty ALDHs of families 3 and 14, and similar sequences, are included in this CD.	0
NC_008312.1|WP_011612221.1|4130681_4133192_+|HDIG-domain-containing-protein	gnl|CDD|224397	COG1480, COG1480, Predicted membrane-associated HD superfamily hydrolase [General function prediction only].	0
NC_008312.1|WP_011612224.1|4135836_4136874_+|NADP-dependent-oxidoreductase	gnl|CDD|381320	cd19094, AKR_Tas-like, Escherichia coli Tas protein and similar proteins. Escherichia coli Tas protein is the prototype of this family. It is an NADP(H)-dependent aldo-keto reductase that catalyzes the reversible reduction of ketones to the respective alcohols using NADP(H) as a hydride donor.	0
NC_008312.1|WP_011612220.1|4129511_4130651_+|ADP-ribosylglycohydrolase-family-protein	gnl|CDD|377122	pfam03747, ADP_ribosyl_GH, ADP-ribosylglycohydrolase. This family includes enzymes that ADP-ribosylations, for example ADP-ribosylarginine hydrolase EC:3.2.2.19 cleaves ADP-ribose-L-arginine. The family also includes dinitrogenase reductase activating glycohydrolase. Most surprisingly the family also includes jellyfish crystallins, these proteins appear to have lost the presumed active site residues.	2.29515e-10
NC_008312.1|WP_011612215.1|4122021_4123299_+|serine-hydroxymethyltransferase	gnl|CDD|234571	PRK00011, glyA, serine hydroxymethyltransferase; Reviewed.	0
NC_008312.1|WP_044137498.1|4143819_4144842_-|sulfotransferase	gnl|CDD|379204	pfam13469, Sulfotransfer_3, Sulfotransferase family.	3.76682e-26
NC_008312.1|WP_155994691.1|4142264_4143506_-|chromate-efflux-transporter	gnl|CDD|273350	TIGR00937, Chromate_transport_protein, chromate transporter, chromate ion transporter (CHR) family. Members of this family probably act as chromate transporters, and are found in Pseudomonas aeruginosa, Alcaligenes eutrophus, Vibrio cholerae, Bacillus subtilis, Ochrobactrum tritici, cyanobacteria and archaea. The protein reduces chromate accumulation and is essential for chromate resistance. [Transport and binding proteins, Anions].	3.49559e-60
NC_008312.1|WP_011612209.1|4110198_4112451_-|bifunctional-(p)ppGpp-synthetase/guanosine-3',5'-bis(diphosphate)-3'-pyrophosphohydrolase	gnl|CDD|223394	COG0317, SpoT, Guanosine polyphosphate pyrophosphohydrolases/synthetases [Signal transduction mechanisms / Transcription].	0
NC_008312.1|WP_011612217.1|4126185_4127463_+|competence/damage-inducible-protein-A	gnl|CDD|234789	PRK00549, PRK00549, competence damage-inducible protein A; Provisional.	0
NC_008312.1|WP_011612211.1|4113608_4114220_+|zf-TFIIB-domain-containing-protein	gnl|CDD|379195	pfam13453, zf-TFIIB, Transcription factor zinc-finger.	2.63359e-09
NC_008312.1|WP_011612222.1|4133384_4134116_-|JAB-domain-containing-protein	gnl|CDD|178801	PRK00024, PRK00024, DNA repair protein RadC.	1.92727e-107
NC_008312.1|WP_011612223.1|4134326_4134872_+|acireductone-dioxygenase	gnl|CDD|380360	cd02232, cupin_ARD, acireductone dioxygenase (ARD), cupin domain. Acireductone dioxygenase (ARD; also known as 1,2-dihydroxy-3-keto-5-methylthiopentene dioxygenase) catalyzes the oxidation of 1,2-dihydroxy-3-keto-5-methylthiopentene to yield two different products depending on which active site metal is present (Fe2+ or Ni2+) as part of the methionine salvage pathway. The ARD apo-enzyme, obtained after the metal is removed, is catalytically inactive. The Fe(II)-ARD reaction yields an alpha-keto acid and formic acid, while Ni(II)-ARD instead catalyzes a shunt out of the methionine salvage pathway, yielding methylthiocarboxylic acid, formic acid, and CO. ARD belongs to the cupin superfamily with a conserved "jelly roll-like" beta-barrel fold capable of homodimerization.	1.95359e-48
NC_008312.1|WP_044136786.1|4127923_4128370_+|type-II-3-dehydroquinate-dehydratase	gnl|CDD|235443	PRK05395, PRK05395, type II 3-dehydroquinate dehydratase.	1.53395e-89

Protein sequences

>NC_008312.1|WP_044136786.1|4127923_4128370_+|type-II-3-dehydroquinate-dehydratase
MFNILVLHGPNLNLLGLREPGIYGSVTLDNINRLLKQEAEAIGVKISISQSNHEGVLVDLIHSSSEQHQGILINAGAYTHTSVAIRDAISGINIPTVEVHLSNIYSREEFRHHSFIAPVAIGQISGFGSQSYLLGLKAIVNYLKNRGD
>NC_008312.1|WP_011612217.1|4126185_4127463_+|competence/damage-inducible-protein-A
MIAEIICVGTELLLGDILNSNAQFLAKQLANLGIAHYYQTVVGDNPDRIKQVLAIATDRSQILIFTGGLGPTPDDLTVATIADFFETPLIERPEIIEDITKKFARRGRIMTASNRKQALIPQGANILPNPIGTAPGIIWQPVQNITIMTFPGVPTEMKSMWQETAIPYMQSQGWCEQTIYSRTLKFWGITESSLAEKVAPFLEKENPTVAPYANYGEVKLRISARATSLELANKLIIPVEEEIKDIAGIDFYGINDESLASVVGKLLLESGETLAVAESCTGGSLGSMLTSIPGSSEYFYGGVISYENQVKITLLDVNLEDLMAEGSVSHVVAKQMASGVVKKLGTNWGISITGIAGPGGGSDTKPVGLVYIGIARYDDIVESFEYRFSNLRDRNWIRRVSVSTALDLLRRKLYLSKQRPQHHQA
>NC_008312.1|WP_044137494.1|4123683_4124745_+|undecaprenyl/decaprenyl-phosphate-alpha-N-acetylglucosaminyl-1-phosphate-transferase
MPNYFYHLITLIISTLLVLLTTPTIKKIALIIGLVDHPGGRKIHKQPMVRLGGVSIFISSLIALLIVWWLGGFIDTNGNILPPEKEFEIWGVTVGGIAFFVIGLADDLFGLSPLFRLFTQIIAASIAWVVGVQIQFLTIPFYGLAHIDILLSWPVTVIWLVGMANAINWIDGVDGLAAGVSGIAAFMMLIVSIFMDQPAAALIAAALAGATLGFLRYNFNPAQIFMGDGGAYYVGFTLAGVGVIGLVKTTMVTSVVLPYLILAVPILDMSAVILDRLRNGKSPFIADKRHLHHRLLDAGLSQRLTVFFIYSLTLWAGSLAMAFSGIPSGTIYAFSATGLLAYTSWKVWKQKQA
>NC_008312.1|WP_011612215.1|4122021_4123299_+|serine-hydroxymethyltransferase
MINANFLADTDPLVAEIIQKEYGRQQDHLELIASENFTSPAVMAAQGSVLTNKYAEGLPSKRYYGGCEFIDEVEQIAIDRAKQLFGAAHANVQPHAGAQANLAVFLTLLKPGDTIMGMDLSHGGHLTHGSPVNISGKWFKAHHYGVNKETEAIDYDQVLELAKKHKPKLLICGYSAYSQIINFEKFRAIADEVGAYLLADIAHIAGLVATGHHPNPVPHCDVVTTTTHKTLRGPRGGLILTRDSELGKKLDKSVFPGTQGGPLEHVIAAKAVAFGEALKPEFKTYSGQVIENAAALATQLQERKLKIVSGGTENHVMLVDLRSVSMTGKKADKLMSGVNITANKNTVPFDPESPFVTSGLRLGSPAMTSRGMKATEFIEIGDIIAERLQNPEDEGIAQKCRERVASLCKAFPLYPHMMAKVPSLV
>NC_008312.1|WP_011612213.1|4118495_4119104_+|nitroreductase-family-protein
MDTLEAIYQRRAIKGFDPNHKITEDDEKKLLEATIQAPTSFNIQHWRFVILRDTELRQKIRELGFDQAQMTDASLLILFTADMKAWGKGVERYWKNAPEQVSNMMVGMTGDFYKDREWLQRDEAQRSIGMAMQTLMLAAKAMGYDSCPMIGFDIEKLAELINLPEDYVIGPMVAIGKKVKDPWPKPGQLPLAELKVENQFTK
>NC_008312.1|WP_011612212.1|4114447_4116106_+|ABC-transporter-ATP-binding-protein
MNPLLSIENLRVAYPEEERKYHWAVNNVSLKLQPGEKLGLVGESGCGKSTLGRAAMRLLPKSAEVEGSVTFKGESLFRMEPSQLRKFRGEAVALVFQDPMTRLDPLMTIGDHCLETLIAHQPHLSKSQAQQKSIETLETVNIPASRWSQYPHEFSGGMRQRVAIALALLLDPKLIVADEPTTSLDVTIASQILQELTKICQERQTSLLLISHDLAMVAEYCDRIAVMYGGEIVEIGAIQQIIQNPQHEYTKSLFAAALHIQVVESTVPQIQSEKSEEITVAKTVKPILQIKDLVKHYTLESNFIEQLLFSGKSKLIKAVDGVNLNLYSGEILGLVGESGCGKSTMTRTILQLIKPTSGSVKFQGTDLTTLSHSALQPYRREMQMIFQDPLACLNPMMTINQIVADPLFIHNLANAEEAKIQVEEILEKVGLTPVSEYGTRYPSQLSGGQQQRVAIARALITNPKLIICDEPVSMLDATIQTQVLKLMLDLRKELSLTYLFITHDLWVARFICDRIAVMNNGKIVEEGKTEEIFNHPQHSYTQMLLNAAPQFW
>NC_008312.1|WP_011612211.1|4113608_4114220_+|zf-TFIIB-domain-containing-protein
MKSPKCDAELEDAILNDIIPVKYCPKSEGFWISAKDYEAWLSSLPVWYAPEETLPYYNQFEDFVPSLFDGKAGLCPECGTYLSRCRINIKQPFYIERCMSCGGIWFDNSEEWNILEELGLHTKINEIFSSQWQARVREHQQEMINRETVIDKLGEEIAEYIFQLTDILETYPQADCAATYMLRRFENKRKELNGTFSIKSQSE
>NC_008312.1|WP_011612210.1|4113225_4113612_+|heterocyst-frequency-control-protein-PatD
MLPKKYNQQYQKLSQLINQLQQNVTEIELEKILANFQEAQGWFETQIINLDSSELDPSIASKIQSYLTEIHKQFKLLNLDVSFLQASQNCQTQKTRLANISDRLKTLKGYCRIILGQDKLIQNQEKTG
>NC_008312.1|WP_011612209.1|4110198_4112451_-|bifunctional-(p)ppGpp-synthetase/guanosine-3',5'-bis(diphosphate)-3'-pyrophosphohydrolase
MKTKTVTPKAQISCVIPDWLQECLDNRNKGNNVTSCSVDTALICRAFEFAYKLHEGQYRKSGEPYICHPVAVAGLLKYLGGDSTMIAAGLLHDIVEDTDVKIEEIEEKFGSEVTLLVEGVTKLSKFNFSNKTELQAENFRRMFLAMAKDIRVIVVKLADRLHNMRTLQHLPSHKQLSKALETREIFAPLANRLGIGRIKWELEDLSFKYLEPNAYREIQELVADKRVDREARLLKMTENLRQKLDRLGIECYDISGRPKHLYGIYRKMYLKQKEFHEVYDISGLRIIVEKREDCYRTLAIVHDSYRPIPGRFKDYIGLPKPNRYQSLHTGVIGITGRPVEVQIRTVEMHHVAEYGIAAHWKYKETGYSNTNVNITTEDEKFTWLRQLLEWQSDLKDDREYLETIKGDLFSEDVYAFTPKGDVISLKHGSTPIDFAYRIHTEVGNHCTGAKVNERIVPLDTPLKNGDIVEILTHKNGHPSLDWLNSVVTGGARNRIRQWYKRSHREEILARGRELLEKELGKKGFESLLKSEQMRLVSEKFNYHNVDDLLAGLGYGEITLNLVVNRLRDAFREVTKVEENSDICSEKYLHKSTQISSPNNYHPIAGVEGLMYHLAGCCNPIPGEPIIGAVTRINGISIHRQGCSNIENVPGERLVPVSWNNANENNGRPKTYPVNIYIEVIDRVGVLKDILSRLMDNNVNVKNAQVKTNPGHTAIINLCIEVSDCQQFERSCTQIKNISDILNLRRVSQVE
>NC_008312.1|WP_011612208.1|4108472_4109852_-|aldehyde-dehydrogenase
MLLDQSSISNLLNKQRKFFATGKTKNIDFRIEQLKGLKQAVSDYQNKIVAAVKADLNRAEFEAYFELTFFPEINDGIKKLKSWAKPRRVSTPIEQFPAGAKIYQEPLGVVLIIGAWNYPFQLVIHPLLGAIAAGNCAIIKPSEIAVNTSEVVADLIAHTFDSSYIAAVTGGVEKSQQLLAEKFDHIFFTGGTRVGKIVMEAAAKSLTPVTLELGGKSPCIVDDDIQLEYTAKRITWGKFINAGQTCVAPDYLLVNKSVKSDLLEKIKQSIDKFYGKNPANSPDYGRIINEKQFNRLNHLLEEGKIFIGGETKSEELYISPTVIEGVNWDSGIMEEEIFGPILPVLEYENLDEAIALVNSRPKPLSLYFFSRNKQKQEQVLRETSSGNVCINDTVMQFVVRFLPFGGVGNSGIGSYHGKASFDTFSHYKSVLNKGLWFDLKFRYAPYKNKVGLIKKIIFW
>NC_008312.1|WP_011612220.1|4129511_4130651_+|ADP-ribosylglycohydrolase-family-protein
MQYSLLKKFQGALLGAVLGNYIGSHFEYQVRKNRGNYKLFINQHKCYLSNSQKNYLQKWGEATFNCAKSLISQQEFNEENWQKVYIEWKNKWEDQKDYTGEPNKIKDSPIELEKLVRRVNDKESNFQYINDDVLIPTASNAIIASLPVSLMYHEDELKLQQKLRQWGNVWQNCLEVNLSNLVIGYTIAQALTERLDPRTIIPKIINYIGEKESIVDQLRQVEKLINQGANLDAAINIFSKNVSFFDNGQISNEGQQKSQSCTFFIPISLALYCFLSTPEDFGLAVLCSARTAWSTQVCAIVSTLSGAYNSIAGVPVEWRQKMGVELLGMKDEVEIMKLAKSLWAVWCGVYDPNNLTQSLVPAVAASNVIRPRPCPANGY
>NC_008312.1|WP_011612221.1|4130681_4133192_+|HDIG-domain-containing-protein
MYLTRLIGILFKPQKKGQVSRWSTLATSPMLVILAIVSLTATMGQRYYNQPELKEGTIAPQIIRVPQDDTVIDHKLTDERRKSARLGDITVFMIDQSVNRKVDKELEEILTVGNKARYMVANFPFVNTGILSTITQRYLRQVSQQKWQAIQKIVEEELQERPPGPESERNVSASSTQKTRKVTNEKNDIIRPTSTDEELSKGKSILAGNQKNSSIVVSSRDKKVISELLTYRKKSLFENYLKVLEEVSLARNFYKNAKKLLAQEQENEGYEVYDHTLLELYDSTWQKTQIGIKTVKDRMLAQGISPNFPKKKWVNAIKAQVVGVLPLETQDLAVNILKNILEPNLAKDQDETRKLVEKEAQNVKPVQYKVRKNEVIVKTGEKINRKAFVLLDNFSLSRRRVNWRSLVVFVCIVSASVAIVVIVGKKFQSCLRRRDHILLLLLSLSAPLLVALRIPWTSSLPAIGLLVGNFYGSTMGVTLVGLISVVLPIGMDVDKIDWFASAVGGIVGSLVVEKMRSREEQALLGVGVGLTQGMVYLLTNLIVRANPGLLWYAIIGPVGWQVLTGLIWGIVALGLSPYLEHLFDLITPIRLSELANPNRPLLKRLASEAPGTFQHTLFVATLAEAAAREIGCNVELVRTGTLYHDIGKMHDPLGFIENQMGGPNKHDEINDPWMSVEIIKKHVTEGLVMARRHRLPKAIQAFIPEHQGTMLIAFFYYQAKQRSEKEEKVIEEELFRYAGPIPQSRETAIVMLADSCEAALRSLKDANHKDALQMVKKILRARWQDHQLVDSGLTRGEISSIAEIFVQVWEQYNHKRIAYPKGAINPNQVKTVKSSC
>NC_008312.1|WP_011612222.1|4133384_4134116_-|JAB-domain-containing-protein
MTYSLRIADLPSNERPRERLIACGSQSLSTAELIAILLGTGQGKGKLSAVGLGQYILNQLSQYERDPLSILRNITVQELTQIHGIGTAKATTILAAIELGKRVFQSRPPELAVVESPQAAADALSQDLMWQTQEKFAVLLLDVKNRLLGTQVITIGTATETLAHPREIFGEVIRQGASRVIISHNHPSGNVEPSPEDINLTKQLLAGAQILDIPLLDHIIIGNGEHSSLRQITNLWEDYPQRG
>NC_008312.1|WP_011612223.1|4134326_4134872_+|acireductone-dioxygenase
MAILKLEDGTIYTQLHDISRELSSLNIQLNHWPVGDNLETHNLLEKDVLSDDQKEEFLQSVDHYFEELKETAGYQSRDLLAIHPEIPNLDAILSKFDKCHTHADDEARYIVAGICIFGFVRPDDSQVELTLQPQEYINIPANTEHWFYLTPEKRVKAVRYFSSTEGWTPHYTSTEIHFKKS
>NC_008312.1|WP_011612224.1|4135836_4136874_+|NADP-dependent-oxidoreductase
MKYNKLGDSNLNVSEICLGTMTYGLQNTIEEAHQQLNYAVAEGINFIDTAEMYPVPSRADTQGKTEEYIGEWLVKQQRDKLIIATKVTGPSPRITWIRGENRKVNRANIQQAIEDSLRALQTDYIDLYQIHWPDRYVPLFGAPDYDPNNEWDSTPIAEQLEVFAELIKAGKIRYLGVSNETAWGLCEFCHLAEKLGLPKIVSIQNAFSLVNRVFHINIAEACRFNNVGLMAYSPLAFGILTGKYLQGVPENSRLAFFPGFDQRYRKTNLTEAIKSYIEIANKNNMTPAQLALAYVNSRWFVASTIIGATTMEQLKENISSVEISLTEEIIAEIDTVHAKYPNPTP
>NC_008312.1|WP_011612225.1|4138434_4140921_-|tetratricopeptide-repeat-protein
MKRIIVTCLIGITTLTTTALILPLLPQSSYAQSSNSQAEKLEQLIKTAQQQIGQYQYQESIETLQEALAIARKIKDRKYEAVANLGLGYVYDQTGQPQKALEFYEKALPIWQEVGYRFGEATTLNNIGGVYSDIGQPQKALEFYEKALPISQEVGARSQEATTLNNIGLVYDNIGQPQKALEYYEKALPISQEVGARSQEATTLNNIGLVYSSIGQPQKALEYYEKALPISQEMGAHSQEATTLNNIGLVYSNIGQPQKALEFFEKALPIWQEVGYRSQEATTLNNIGNVYSSIGQPQKALEYLQKALPIMQEVGARSLESTTLSSIGKVYRDSNQPEKAIDHLEKSVKITLEIRGGLKKENRKTFLNFQYNKWTPIALIDLLIDQNQPEAAWKWYNLATTFDLADYTRLIKAKVKNPEAQKLINQWEENYQKLQALYSKIEDGTTTQLSQQIKQLQAENNQLAENASQKYPEVAELFEFEPKDIDKLKANIPPGTVVIQPALLTGLKSVPDSIAIFLVTRDQATLVKKLPIDAKEFDSILTEYRSQLEKPNADNYATNQEKLYDYLIRPIETEIAAYSPKRLAIIPTGKLRYIPFETLYDNQTEQYLIAKYPIHYLTRISATRQEPKEPTKSLKVLAFGNPQPTEINLRGAEDEAKIIAENLSGKSLTREKATLSSFENESPGFPLVHLATHGCFQKGGCREQGLEENTILFANNKTFNIANAARLGLENTDLIALSACQTAMKADSNGEEIAGVAYLFERAGADAVIASLWNAEDGTTKDIMVKFYDNLKQGMTKVEALRQAKLSYARSDVSPFYWSPFILIGDGE
>NC_008312.1|WP_011612226.1|4141096_4141306_-|hypothetical-protein
MGVDGLVWTNADQNPIEIKPESVIRVDEREGIPREMRNIINSRYVVSKMEFEPERQIWIITATLKSRKE
>NC_008312.1|WP_155994691.1|4142264_4143506_-|chromate-efflux-transporter
MTDTSIPNDAKSKLKKESFLFWAFLKIGSTAFGGFMALVSVCESMIVQQHKLLSHEEMLDGISLATVLPGPVAVNVVAYIGYKIRGIRGAFASTTGVLLPTYLLVVSFTAFYFRVGEISAISKAFAGFIPAMVAIILVAIWRLSKKTIRTLKNWKSISIAVAAFIILKFVGGFYTTLLIVLGSGIFGYLLYYDATASELSTSNISSPITSPLISKTKLLLSSFVLSAFLVLYLVPLPFLENTSLAKLFIVFSGMSLTLFGSGYVFIPMIQEIVVNNYGWVTQTEFASAIALSQITPGPILISAAFIGYAVKGILGSLVATIGIFFPPAMLMITCSDLLEQIKNSSTIQTALKGVRPAVIGMIFAAALILLQGVKIHWVSALILMGGLFAILRFKVDVILVIPVAGILGILLYP
>NC_008312.1|WP_044137498.1|4143819_4144842_-|sulfotransferase
MPIIMIGTQRSGSNLLRLILNEISIIAAPHPPHIIQRLMPLLFTYGDLSVSKNFKQLVNDTCQLIKLNPVPWERIKFDRNNILSRCMENTLVAVFSSVYDIYAEAWDAKIWCCKSLANVHYFPQINAYLPNAKYLYLYRDGRDVAVSFKEAVVGQKHFFHIAQQWRKDQHAALKIKKQLRGEQFFSLSYEDLINSPELSLYNLCGFLELEFSPTMLDFYNSREASNTSSSSTLWSNVSKPIIKKNSNKFLSKATKEEVKIFESVAGDVLDSLGYERNQTNMGEFRTFSQEEIAQFDLQNEKAKAQVRDMIDVKDKKRREQQLSLLEAIKSRCSLIDSKTY
>NC_008312.1|WP_011612229.1|4144887_4145262_-|hypothetical-protein
MTRITIIFLVACLTLMARETREAIANPKSIVQAEAKPTVKPIPVSLPRNGTVLLNSGDSRSGSVIDVNSEYITVKKGRSRRREAIANVKEIRFYGDLWWPASDGIIVIRGDDVDKIGKIRRFEE

Crispr_ID: NC_008312_32

• CRISPR_ID: NC_008312_32
• CRISPR_location: 4183016-4183244
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 2 spacers
• Cas_protein_info: DinG

Consensus repeat of NC_008312_32

Consensus_repeat	Method
TATTAAATGGTGGTCAAGGAAATGATATTTTAAATGGTAAT	PILER-CR

spacers of NC_008312_32

>32.1|4183057|40|NC_008312|PILER-CR
GATAGTTCCGATTACCTTCGAGGGGGAAAAGGATTAGATT
>32.2|4183138|67|NC_008312|PILER-CR
TTAGATAATGATACTTTATTAGGTGAGCAAGGAGATGATTTTTTACGGGGTGGTAAAAATAATGATA

CRISPR arrays and Neighbor proteins around NC_008312_32

CRISPR arrays

The CRISPR arrays of NC_008312_32

>merge|NC_008312|32|4183016-4183244|PILER-CR
TATTAATGGTAATCAGGGAGATGATATTTTAAATGGTAGGGATAGTTCCGATTACCTTCGAGGGGGAAAAGGATTAGATTTATTATTTGGTGGTCTTGATAATGATATTTTAAATGGTAATTTAGATAATGATACTTTATTAGGTGAGCAAGGAGATGATTTTTTACGGGGTGGTAAAAATAATGATATATTAACTGGTGGTGAAGGAAATGATATTTTAATTGGTGAT

>NC_008312|32|1|4183016-4183244|PILER-CR
TATTAATGGTAATCAGGGAGATGATATTTTAAATGGTAGGG	ATAGTTCCGATTACCTTCGAGGGGGAAAAGGATTAGATTT
ATTATTTGGTGGTCTTGATAATGATATTTTAAATGGTAATT	TAGATAATGATACTTTATTAGGTGAGCAAGGAGATGATTTTTTACGGGGTGGTAAAAATAATGATAT
ATTAACTGGTGGTGAAGGAAATGATATTTTAATTGGTGAT

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_008312.1|WP_011612262.1|4201887_4202796_+|hypothetical-protein	unknown	unknown	gnl|CDD|223469
NC_008312.1|WP_011612253.1|4180081_4181143_-|AI-2E-family-transporter	unknown	unknown	gnl|CDD|223701
NC_008312.1|WP_011612247.1|4170842_4171718_-|alpha/beta-hydrolase	unknown	unknown	gnl|CDD|223669
NC_008312.1|WP_011612254.1|4181554_4182106_-|peroxiredoxin	unknown	unknown	gnl|CDD|239315
NC_008312.1|WP_011612261.1|4199214_4200150_-|hypothetical-protein	unknown	unknown	unknown
NC_008312.1|WP_011612256.1|4184502_4186056_+|cyclophilin-type-peptidyl-prolyl-cis-trans-isomerase	unknown	unknown	gnl|CDD|238905
NC_008312.1|WP_011612263.1|4203101_4204340_+|MFS-transporter	unknown	unknown	gnl|CDD|341042
NC_008312.1|WP_011612265.1|4205398_4205656_+|2TM-domain-containing-protein	unknown	unknown	gnl|CDD|379083
NC_008312.1|WP_011612245.1|4166809_4167943_-|DegT/DnrJ/EryC1/StrS-aminotransferase-family-protein	unknown	unknown	gnl|CDD|99740
NC_008312.1|WP_011612249.1|4173785_4173998_-|DUF2839-domain-containing-protein	unknown	unknown	gnl|CDD|371332
NC_008312.1|WP_011612248.1|4172627_4172993_-|DUF1815-family-protein	unknown	unknown	gnl|CDD|285990
NC_008312.1|WP_011612246.1|4169524_4170607_+|recombinase-RecA	unknown	unknown	gnl|CDD|236476
NC_008312.1|WP_011612264.1|4204509_4205010_+|cyclic-pyranopterin-monophosphate-synthase-MoaC	unknown	unknown	gnl|CDD|236483
NC_008312.1|WP_011612250.1|4174531_4176070_-|helicase	DinG	COG1199_DinG_CAS-IV-A	gnl|CDD|224120
NC_008312.1|WP_011612251.1|4176774_4178328_-|hypothetical-protein	unknown	unknown	gnl|CDD|224276
NC_008312.1|WP_011612259.1|4192356_4195296_-|DUF563-domain-containing-protein	unknown	unknown	gnl|CDD|368006
NC_008312.1|WP_011612258.1|4187461_4191922_-|tetratricopeptide-repeat-protein	unknown	unknown	gnl|CDD|133027
NC_008312.1|WP_011612260.1|4196544_4197528_-|calcium-binding-protein	unknown	unknown	gnl|CDD|380205
NC_008312.1|WP_155994695.1|4186207_4186903_+|pentapeptide-repeat-containing-protein	unknown	unknown	gnl|CDD|224276
NC_008312.1|WP_044137508.1|4178364_4179213_+|prephenate/arogenate-dehydrogenase	unknown	unknown	gnl|CDD|180970

HMMScan for Signature genes

Protein	Cas_name	Cas_description	E-value	Identity	Coverage
NC_008312.1|WP_011612250.1|4174531_4176070_-|helicase	DinG	COG1199_DinG_CAS-IV-A	2.2e-28	93.6	0.0

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_008312.1|WP_011612262.1|4201887_4202796_+|hypothetical-protein	gnl|CDD|223469	COG0392, COG0392, Predicted integral membrane protein [Function unknown].	2.64218e-05
NC_008312.1|WP_011612253.1|4180081_4181143_-|AI-2E-family-transporter	gnl|CDD|223701	COG0628, yhhT, Predicted permease, member of the PurR regulon [General function prediction only].	3.56349e-46
NC_008312.1|WP_011612247.1|4170842_4171718_-|alpha/beta-hydrolase	gnl|CDD|223669	COG0596, MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [General function prediction only].	5.69242e-41
NC_008312.1|WP_011612254.1|4181554_4182106_-|peroxiredoxin	gnl|CDD|239315	cd03017, PRX_BCP, Peroxiredoxin (PRX) family, Bacterioferritin comigratory protein (BCP) subfamily; composed of thioredoxin-dependent thiol peroxidases, widely expressed in pathogenic bacteria, that protect cells against toxicity from reactive oxygen species by reducing and detoxifying hydroperoxides. The protein was named BCP based on its electrophoretic mobility before its function was known. BCP shows substrate selectivity toward fatty acid hydroperoxides rather than hydrogen peroxide or alkyl hydroperoxides. BCP contains the peroxidatic cysteine but appears not to possess a resolving cysteine (some sequences, not all, contain a second cysteine but its role is still unknown). Unlike other PRXs, BCP exists as a monomer. The plant homolog of BCP is PRX Q, which is expressed only in leaves and is cellularly localized in the chloroplasts and the guard cells of stomata. Also included in this subfamily is the fungal nuclear protein, Dot5p (for disrupter of telomere silencing protein 5), which functions as an alkyl-hydroperoxide reductase during post-diauxic growth.	6.91949e-66
NC_008312.1|WP_011612256.1|4184502_4186056_+|cyclophilin-type-peptidyl-prolyl-cis-trans-isomerase	gnl|CDD|238905	cd01924, cyclophilin_TLP40_like, cyclophilin_TLP40_like: cyclophilin-type peptidylprolyl cis- trans isomerases (cyclophilins) similar ot the Spinach thylakoid lumen protein TLP40. Compared to the archetypal cyclophilin Human cyclophilin A, these proteins have similar peptidylprolyl cis- trans isomerase activity and reduced affinity for cyclosporin A. Spinach TLP40 has been shown to have a dual function as a folding catalyst and regulator of dephosphorylation.	1.22432e-66
NC_008312.1|WP_011612263.1|4203101_4204340_+|MFS-transporter	gnl|CDD|341042	cd17489, MFS_YfcJ_like, Escherichia coli YfcJ, YhhS, and similar transporters of the Major Facilitator Superfamily. This subfamily is composed of Escherichia coli membrane proteins, YfcJ and YhhS, Bacillus subtilis uncharacterized MFS-type transporter YwoG, and similar proteins. YfcJ and YhhS are putative arabinose efflux transporters. YhhS has been implicated glyphosate resistance. YfcJ-like arabinose efflux transporters belong to the bacterial MdtG-like and eukaryotic solute carrier 18 (SLC18) family of the Major Facilitator Superfamily (MFS) of transporters. MFS proteins are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	5.46288e-73
NC_008312.1|WP_011612265.1|4205398_4205656_+|2TM-domain-containing-protein	gnl|CDD|379083	pfam13239, 2TM, 2TM domain. This short region contains two transmembrane alpha helices that are found associated with a wide range of other domains. This domain may be involved in cell lysis or peptidoglycan turnover.	1.10127e-07
NC_008312.1|WP_011612245.1|4166809_4167943_-|DegT/DnrJ/EryC1/StrS-aminotransferase-family-protein	gnl|CDD|99740	cd00616, AHBA_syn, 3-amino-5-hydroxybenzoic acid synthase family (AHBA_syn). AHBA_syn family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The members of this CD are involved in various biosynthetic pathways for secondary metabolites. Some well studied proteins in this CD are AHBA_synthase, protein product of pleiotropic regulatory gene degT, Arnb aminotransferase and pilin glycosylation protein. The prototype of this family, the AHBA_synthase, is a dimeric PLP dependent enzyme. AHBA_syn is the terminal enzyme of 3-amino-5-hydroxybenzoic acid (AHBA) formation which is involved in the biosynthesis of ansamycin antibiotics, including rifamycin B. Some members of this CD are involved in 4-amino-6-deoxy-monosaccharide D-perosamine synthesis. Perosamine is an important element in the glycosylation of several cell products, such as antibiotics and lipopolysaccharides of gram-positive and gram-negative bacteria. The pilin glycosylation protein encoded by gene pglA, is a galactosyltransferase involved in pilin glycosylation. Additionally, this CD consists of ArnB (PmrH) aminotransferase, a 4-amino-4-deoxy-L-arabinose lipopolysaccharide-modifying enzyme. This CD also consists of several predicted pyridoxal phosphate-dependent enzymes apparently involved in regulation of cell wall biogenesis. The catalytic lysine which is present in all characterized PLP dependent enzymes is replaced by histidine in some members of this CD.	3.63141e-133
NC_008312.1|WP_011612249.1|4173785_4173998_-|DUF2839-domain-containing-protein	gnl|CDD|371332	pfam10999, DUF2839, Protein of unknown function (DUF2839). This bacterial family of unknown function appear to be restricted to Cyanobacteria.	9.83247e-34
NC_008312.1|WP_011612248.1|4172627_4172993_-|DUF1815-family-protein	gnl|CDD|285990	pfam08844, DUF1815, Domain of unknown function (DUF1815). This presumed domain is about 100 amino acids in length and is functionally uncharacterized.	3.37165e-60
NC_008312.1|WP_011612246.1|4169524_4170607_+|recombinase-RecA	gnl|CDD|236476	PRK09354, recA, recombinase A; Provisional.	0
NC_008312.1|WP_011612264.1|4204509_4205010_+|cyclic-pyranopterin-monophosphate-synthase-MoaC	gnl|CDD|236483	PRK09364, moaC, cyclic pyranopterin monophosphate synthase MoaC.	4.32866e-93
NC_008312.1|WP_011612250.1|4174531_4176070_-|helicase	gnl|CDD|224120	COG1199, DinG, Rad3-related DNA helicases [Transcription / DNA replication, recombination, and repair].	5.25757e-34
NC_008312.1|WP_011612251.1|4176774_4178328_-|hypothetical-protein	gnl|CDD|224276	COG1357, COG1357, Pentapeptide repeats containing protein [Function unknown].	3.2053e-41
NC_008312.1|WP_011612259.1|4192356_4195296_-|DUF563-domain-containing-protein	gnl|CDD|368006	pfam04577, DUF563, Protein of unknown function (DUF563). Family of uncharacterized proteins.	6.27357e-57
NC_008312.1|WP_011612258.1|4187461_4191922_-|tetratricopeptide-repeat-protein	gnl|CDD|133027	cd04184, GT2_RfbC_Mx_like, Myxococcus xanthus RfbC like proteins are required for O-antigen biosynthesis. The rfbC gene encodes a predicted protein of 1,276 amino acids, which is required for O-antigen biosynthesis in Myxococcus xanthus. It is a subfamily of Glycosyltransferase Family GT2, which includes diverse families of glycosyl transferases with a common GT-A type structural fold, which has two tightly associated beta/alpha/beta domains that tend to form a continuous central sheet of at least eight beta-strands. These are enzymes that catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds.	1.27272e-78
NC_008312.1|WP_011612260.1|4196544_4197528_-|calcium-binding-protein	gnl|CDD|380205	NF033203, entero_EhxA, enterohemolysin EhxA. Members of this family are the RTX toxin called enterohemolysin or EhxA, because it is found in enterohemorrhagic Escherichia coli (EHEC) strains such as O157:H7.	1.24423e-19
NC_008312.1|WP_155994695.1|4186207_4186903_+|pentapeptide-repeat-containing-protein	gnl|CDD|224276	COG1357, COG1357, Pentapeptide repeats containing protein [Function unknown].	1.80471e-27
NC_008312.1|WP_044137508.1|4178364_4179213_+|prephenate/arogenate-dehydrogenase	gnl|CDD|180970	PRK07417, PRK07417, prephenate/arogenate dehydrogenase.	0

Protein sequences

>NC_008312.1|WP_011612254.1|4181554_4182106_-|peroxiredoxin
MRSRRHFQTIFLVICLALITWLNFIPNAWALGGKLPELDQPAPEFTLPTNIGDREISLSDYRGQWVVLYFYPKDFTSGCTIEARRFQQDLPKYRERNTQILGVSADDINSHQEFCDSEGLKFPLLADTDGTVSKAYGSWLNFFSMRHTFIINPGGILQEIFLGVKPTIHSQEVLSSLDNLQQT
>NC_008312.1|WP_011612253.1|4180081_4181143_-|AI-2E-family-transporter
MLKLLNQRLFWYLALPIIVINGWALLQIFQYFGRIITIAVSATLLSFLLDYPVLFLQKHGGKRHRAVILVFLVALVIMLVLGVILIPLLLEQLTGFIEKLPSWLESGNKQLESFDQWASKYQLPINLTVITNKLTERLSSQLQDITGEIISFVLNMVGRIFDILITIVITFYLMLHGDRLWNGIFNWLPNHLDIHVRTSLKQNFQNYFLGQAMLACLMGVSMTLGLLFTGTPFGLLFGIGIGLMTLVPFGTALGVTIVSLLITLENFWLGIKVLIVIVLIEQAIENFVAPRILGSFTGLNPVWIVLSLLVGMQVWGVLGLLIAVPVAGFVKNTVNYLFSKSYGQEAKSEIILD
>NC_008312.1|WP_044137508.1|4178364_4179213_+|prephenate/arogenate-dehydrogenase
MNIGIVGLGLIGGSVGLDLRTLGYPVFGVSRREQTCQKAIALGAVDEASLELSLLSIADLIFICTPISYIIPTLEELIPFLSPSAILTDVGSVKVPIVEGVSKIWPNFVGGHPMAGKAESGIEFAQLGLFEDRPYVLTPNENTPLESVKKVEAIAKLLKSKVYFCDPYEHDRAVAWISHLPVMASSCLISACMSESNPTIVKLAREFASSGFHDTSRVGGGNPELGRMMAEHNCLEVLRSLISFRDEIDELIQYIERKDWQIIEEKLRYTEQNRRLFFGNKN
>NC_008312.1|WP_011612251.1|4176774_4178328_-|hypothetical-protein
MIIEELQEKYAAGERNFTNLNLFEANLAGMNLSGVNLSGVNLSIANLSGTNLTNSNLSKAKLNITKLNGAHLSGTNLNGADLNVANLVLVNLKRAQLIGAKLIRAELIRAQLSGANFSLADLSGASLVEATLRKTNLSGANLKGANLRFAFITESNLIEANLEGADLSGADLSGSDLSGAELRKSNLTGANLNGANLSGANLRWAVLTGAQMNCVNLSDAKLSGADLSRANLFQANLLNASLVHVNLSSACLIEVDWIGADLTGANLTGAKIFGTSRLGIKTEAVTCDWLDLSPNGDQPQVYTLNTLKIKSFFHETLPKVKIIVDTRLDISSHYALAATYYQISKYLPDINQPPCIEVNSCRTIISFSMNSDEKIFAVAYITVLPFLDGYKTQENIIKIMKILNSHDFNSLTPIVAKIIRQLSTVLNKSIQQVNKINKDKVLLKFCRGVQFFQTPTKITVINSSGKNFHVYHHPRFGKRIVNKVSKSTEGEVRIQVPQTVPYSINTIIDFIDGFHKP
>NC_008312.1|WP_011612250.1|4174531_4176070_-|helicase
MIEVEVHQSLLNFLRSQNQPHWPHNLTMARLVARALRLGRSALIQTASPPGSRNQQYQLSYLLPVLMWPRKTILVAPQPVQEHLITVEIPKLMASNSQISSSISKKGIQIYPLQEPDFNGLLLMKPKAWLVSQCQDDHFSKGIPTIIDWADYLENWVQSFLTTSFLPTNWNQLMQFYPDQADLIRETRVNLTKSLFQHPANPYSCYLIEQHEQQILQNLIEGLSLTLRNQELQSHNLNHNFWYQWQSNGQLRWAEIHRQRGSFSLYSTPYDLSEALKNIWTKQPVVIIGGALDLEAKADTYRQNMGLGNITCVKFSPDRHNEMIQLYLPNSLPMPNTPQFQPALISEIRTLLHISSSVINRLIVLLIGDVPLKSQVGTTLASEFGSRVQVETVFSEENGILITGWEFWQQHQKEFKPPKLLIIATLPLPSLEHPLVSGRVNFYKQQGLDWFRLYLLPKALQDMQRAITPVRESQGIVALLDSRVIRRSYGQQILTALSPFAKIDYLDTTWLI
>NC_008312.1|WP_011612249.1|4173785_4173998_-|DUF2839-domain-containing-protein
MGEAKRRKEALGENYAQEARFISWLPITKSQSQKFMQLTTTGAWIGIGLLVVAWLIIRFIGPAFGWWQIE
>NC_008312.1|WP_011612248.1|4172627_4172993_-|DUF1815-family-protein
MFLRLTEQHRQFIQDLVMNLQALATVLERRGYLASCYTCGGQMNSASFMVSLGENHQIRFLVSDYGITWTEMRDDRELMKLEGTEAISQLQELANLLKNQIQPCQKPNKLQQAYLSLNKGI
>NC_008312.1|WP_011612247.1|4170842_4171718_-|alpha/beta-hydrolase
MNILESQWKHFFIDTNDIRLHCVTQGEGELVILLHGFPEFWYSWRYQMPALARHFKVVVPDLRGYNDSDKPDNGYDLDTLAADIRGLIERCGYVKAHIVGHDWGGAIAWHLAQKFPQHLNRLAILNAAHPQKFVQELLGNLDQLRRSWYILAFQVPGIPEWVIQQNLGEFIKGLFQGQAIRKSAFTAEITQIYQAALEKPGALVAAINHYRQFLWPQNWLKNFNKPQLVTSPTLILWGKEDYFLSQKLTEGLDKLIAAPFQLKVIPDCGHWIQQEVPHTVNRELLNFLRKK
>NC_008312.1|WP_011612246.1|4169524_4170607_+|recombinase-RecA
MASATDNKEKQKALDSVLKTIEKTFGKGSIVRLGDATRMKVETISSGALTLDLALGGGLPKGRVIEIYGPESSGKTTLALHAIAETQKSGGIAAFVDAEHALDPTYAAALGVDIENLLVSQPDTGEMALEVVDHLVRSVAVDIVVVDSVAALVPRAEIEGDMGDSHMGLQARLMSQALRKITGNIGKSGCTVVFLNQLRQKIGVVYGNPETTTGGNALKFYASVRLDIRRTQTLKKSSEEYGIHAKVKVAKNKVAPPFRVAEFDIIFGKGISNVGCIIDLAEETDVIKRKGAWYSYQGSNFAQGREKAIAYMESNIDFAKKIEKQVRDHLSQGALVSANSVARVDEIEEDEDEDEALEEE
>NC_008312.1|WP_011612245.1|4166809_4167943_-|DegT/DnrJ/EryC1/StrS-aminotransferase-family-protein
MLKNIPFIDLKLQHQPLESEFKKSIQEVLERGDFILGQAVAKFESSFATTCGVENAIGVACGTDAIALGLQACGVSAGDEVILPANTFIATLIGVLHTGATPVLVDCDEETALIDLEIAQKAVTNKTKVILPVHLYGQMVAPSKLLDFAQANKLIIFEDAAQAHLAQREGYRAGSIGTAAAFSFYPSKNLGCFGDGGMVVTSDQKVASKMRMLRNYGAPRKYVYEELGTNSRLDTLQAAVLNVKLPYLKGWNSDRNQAAQKYDTLLSPMKEKGIIPIQNLSGTGHIYHLYVIRITDKSPIDRDTLKDKLGVAGISVGIHYPIPCHLQPAYQHLGYKKGDFPNSETLSQQILSLPMYPVISEEQINLVVETIIQIISQ
>NC_008312.1|WP_011612256.1|4184502_4186056_+|cyclophilin-type-peptidyl-prolyl-cis-trans-isomerase
MDKTQKFLEQLDLPDLSDQDVVVEMVIQKASQQEETESQQEDIESQEEDTESQEEDTESQQEEAEGQEEDTESQEEDTEGQQEEAEGQEEDTESQEEEAGQREKITIQLNTSSAPVTAANFADLVEKNVYDSLAFHRFVEGFVIQGGDPQGRDPDFPIEDLGGGGYIDLETDEKREIPLEIKIAETGEIVYNEETDEAVALSHEAGVIAMARTQELDTASSQFYFALEDISDQLDGGYAVFGKVSDGFDFLQEIQEGDRILIARVVEGNISSRESDLVTDSDLFNELANKDGTNKVKYLISMDENSENNADSDDSTPDIGDPIEPERSQSQITQDENQATNGDDVIVINQVDESSVVMGLKGNDEITGSDGNDLISGNQGNDSLLGLEGNDWLRGGKGDDELTGGMGDDYLIGDHGTDILTGGAGADSFILRSNTAIEEIEEADMITDFNVGDNDRIIVIAEFTSSEGLSYEFIDNDTVIRLLDNSFILGVVKQTSIENVENNILVVNSDDYALRLG
>NC_008312.1|WP_155994695.1|4186207_4186903_+|pentapeptide-repeat-containing-protein
MKITLAMKFLATVTFVISFIYLSLSAPIMGANYEDVNHLLEYNWCVSFLWKQCDLTRANFHDINLKNANMSGANLTGVNFQGADLNGANLSGANLTGANLEKANLYRADINRANLTNTNLTSTRLLEADLTLANLNHANLTDANLLEARLWGASLAGANLNNASLHGTNLEYANLADSNLSGADFHSFSFRSYKQETNLSNANLEGAIITNTDLSGVIMRGTIMPDGSINE
>NC_008312.1|WP_011612258.1|4187461_4191922_-|tetratricopeptide-repeat-protein
MASINPQETAAENFHKKAEAYLAEKKFDEAIASCELAIKIEDNYFPAYKTLGNTWQAQGKLAEAENWYKKALEIKSNWPEIYANLGSLYAMQQKWEEAISYYQKAVDIKPDFAGAYRNMRKVWLSLGNQKLATYCQYKVLSIEPEKATFEEFMNVGKTLEKEGSLNDAISCYRMATKLNSNSSEAYQNLGEALKEQGNLDEATVCCRKAIELKVNGKKIENSDDTLGAASKYNLISSQELNSGDTLVGSLSSNKVNGHNTLVRATIPTTSPTVNAEDIETYMVEAETYVNQKKWEQAIAVSKQVIQTKTEPKAYKIIGNSLQAMGKLQEALDWYNKALKIKPDFGEVYANIGTIFAQQKQWGQAIQNYLRAIEIKPEFAGAYRNLAKIYTQVNKSQEAAEYLYQAIRLEPGKATAQDFLFTGNTLSENGKLEQAIACYQQLISADPNSFEAYEKLGDSLLKQGQLELSLQNYKNAQKLKPYSTEIKQKIGEIYYRYGEYFQKKEKVEEAVKAYRQAIENYPQYDIPYGKLGEVFSQQEKWEEAVKVYEKASQIKPDNSWYYNSLGEALKKLEKWEEAVMAYRKAIQLNPDFSWSHNNLADCLVKLGKREEAVVAYRQAIKLKPDFTWSYINLGNTLWEIGNWQEAINPYSRALELKADLPETYQKLGHALKKRAELDLEESIKWYRKAIENDPDNEKLYHKALEVKPEDHTLYLQLGNTLVKKGKTHGAIAFYQLGLQINPDDSEIQGQLEKILPKKNTLREKKKDNRKKNKVPIFPLPSSPVIEKNEEKKVPISPLPSSPVIEKEDTYQLWLKENLPNSDQLKKMSENLKIFRYQPLISIILQEKSGSPYIQKTIESLINQIYPNWELCYISDKLPQNIEANNKIKLVIKSENRDIATDLNAALALATGDFVTLLNPEDILTPDALYEMVLFLNRYPDSDMIYSDEDKLTSEGKLIEPYFKPNWSPDSFLSRMYTGHLCIYRRELLEKLNGFRVGYESSYEYDLILRLSEVSQKIFHIPKVLYHSRIPENGGEIDWEISKETTKKTLTEALARRGEMGTVYSVPNHPGFYRVRYQISEQKLVSIIIPTRNLGNILDRCLESIFTQTTYPNYEVIVIDNGSDEPETLSIIEKWKNQQPERFKCYEKNIPFNFSKLNNYAVEKAEGDYLLFLNNDTEVKTADWLEAMVEQAQRETIGAVGALLLYPDNTIQHAGVVLGMRSVADHSHRGFSPTDAGYKGQIISVNNYSAVTAACLMCRREVFEQVGGFDEELAVAFNDVDLCLKIIYKGYRNIYLPHAVLYHHESKSRGVENTGEKQLRFQQEIQNMKQRWKDLIDEDPCYHPHLTRQQEDFSLRVQTNVEVALSMYDKDPEIVGCSIDVPSPGVKQNISSICIGGWVVGKKSSPVTVKLISLTKSGKVLREVPANLHRPDVGKIHPEYPYAQHSGFWGEIEVIEIAPESKISLEAIFKDGSHVRLGMVSFKCPNLI
>NC_008312.1|WP_011612259.1|4192356_4195296_-|DUF563-domain-containing-protein
MKIEKYLRLAKSYLTKGNLSQAIEICEQILEIQPNSAHAYRILGEIYQAEENFEKAMYAYTKAVEIQPKYAEVHAFLAWLYSQKKWLSEAANQYQKAINLGLKWPELYYNLGNIFYQVRYFESAIQCYENAIVIKPNYINAYLGLGIIFERERNYQAAVDIYRKVIELNPDFVEGYNNLGRILANWNRRSEAIEVYQQALVLKPDSASLYNNLGFTLLNENPIEAIAAYYRAIELDPLLIKAHYNLGKALQIIGEHELAVKSFQEVIRLKGKKDNLLVYSDCAFSLMTIGKFQTAFVYLKNVITNNKFVDGCWQVLESKLGNLEHIEYDKMYLTKVAVLNFIKELKKLDINSENYQQSSQKISRYLLSYYINFGNVLMENEFYKSAENIYHKALKIKPNSADIYWLLGNNLAKQKRLNSAIISYQIALQILLNENRINQTTKIYFELGKIMEKQQRWQAARDYYSKVLSGKVEDILNNDFNNDFLPYPKLEGLYLSTKDWLQKLDGNNYQKRYKEVRLEKLATEYREESIKSPIKVSVENKKKDLECLGLNCSACLKQIYQWFDPKSPAQGIYSLRDQGEFSQDIDLLSQEISLLNPLEKEGKKSLTPGKNERMSPSSLTSVSKEESILSLTKDTKNDKEGLSYFQKLSRSPTFVTTVPEGRAWIMPKKNYWRLCYGIAIMTPDNYLLSDLSREYPSPLPGCTKHDPSQHRIFGFEELPPLEKINGKVAVLSVLSGNVYFHWMVDLLPRIEILRQGINLEEIDWFIVNDYQQPFQRETLKTLGVKQEKILASDRHPHVQATELVVPSYPSYLGWLQPWGLKFLREVFLRGITNNKSYFPEKIYIGRGNAKYRRVMNEAEVVDILRQFGFTYVTPESISLENQISTFAHAKIIVAPHGSGLTNIVFCNPGTKVIELFSPHYLRYYYWHISQLLGLEHYYLIGETFSCYPMRNIMYESSLVEDILVNLDSLNQMLKVVDIF
>NC_008312.1|WP_011612260.1|4196544_4197528_-|calcium-binding-protein
MTSLIDGNINDLINNIPEEEQPDGGFDTLPTVDRPIEGGDGGRDIQGGPTADAIEGSTASDVVSTGAGDDLVAAGDGDDDVLLGTGDDTVLAGTGVDTISGNQGNDSVAGGAGDDLLYGGKGDDSVEGGEGADFVFGDRGSDLVQGGAGDDVALGGRDSDTVTGDEGNDTLDGGKGDDILSGGVGDDFLFGGKGSDTLTGGTGADKFLFYYNEDGSYGLDSLTDFNRDQGDKIGIVVNNFGGGNFEALTGARPGDSLSGAQFAVVENFSPNEDGANSAAIIYDPDTGLVYYNPDGSAVAGNETPIARVDNTVFDSNNPLQGTDFEIF
>NC_008312.1|WP_011612261.1|4199214_4200150_-|hypothetical-protein
MTFFNKDEQLNILGKDIIEATQLEFSELTSEAIAITWLVYNSPITRNIQNATEFWQKQVRGWSDRGDEKMYAGGMVHLFYLVAIYEWLEKGMVKTSPELERAIRDMILSANHDGTSLVVDVLTGTTSGPELSPGPFQTWKYQRNFINRYFQSLKWPELKSINVNQKTWFYGPYGRERIFQGLLMENRNILTTNATARLLHSIVGGIAVSRQASGKIMDLLQKNLSQQDAKYVTKSQTIGFLKESLPQNAKIWSREIVDTHVHHNFAYIELPNLLPYLLVIFTEGKEISKNERILPYISQKFVEAMKKLSLK
>NC_008312.1|WP_011612262.1|4201887_4202796_+|hypothetical-protein
MKKVLSDIKPYLRWIILGATLFFLVKTLKDNWEQVLQIRISDSGWISLGTAFLITIMAHVWSGWVWFWIIKEFNQLVNFPWAIRVYLLTNIAKYLPGNIWHFYGRITEVKKVGVPIEIAILSVLIEPLLMAAAALIVALVGSTQESFFLQLFCFFSVICIIHPRILNPIIKCLVKIKLKFKKIDLEPDNELVLERYPIKPFVGEVCFVLLRGSGFLLTILAFNSIEFNQILLIFSAFSFAWLLGLVVPGAPGGVGVFEATALALLEQKFAPGIVLSAVAFYRLISVLAETFAAGLAWLKQKI
>NC_008312.1|WP_011612263.1|4203101_4204340_+|MFS-transporter
MKVFKTLDPKQQRSLMILFLAGLLFWSSITTLLPTLPLYLNYIGGTKQQIGFVLGCFSMGLLLSRFILAPIADTKSRKLVLIVGTSVAAIAPLGYLLFKSFLFLMLVRAFHGISIAGVTIGYTALVADLSPPGRRGELIGYMSLCTPIGMAIGPTVGGFLVEANEYVPLFIVCSTLGIASLLFSILVSESSAIAQKNLHSHQFEQQKLWQILGSRRVLVPVFVMLIVGLIFGTTTTFLPLYIQENSIALNAGIFYTVRGITNLLIRIFTGRASDKFGRGVFISSGLVFSLLGMLTLWTANSRNMILLAAILGGSSSGLILPMMITLMTDRCPPDQRGKFFSLCIGGFDVGIAIAGPTFGLVAEQIGYRSMFAIDAILASIAIATFITLSNSNLPHSIRFAFGRGQDTYAINH
>NC_008312.1|WP_011612264.1|4204509_4205010_+|cyclic-pyranopterin-monophosphate-synthase-MoaC
MTRDFSKFEQNLTHLDSEGAVKMVDVSTKVQTIRQAEAAGQVRMLPETFEAIQRGNSPKGDVLGTAKLAGIMAAKQTAQLIPLCHPLPLQKIDIELIPDPHLPGYQIRAMVKTKAETGVEMEALTAVSVAALTLYDMAKALEKSISIELIRLLSKSGGKSGDYMVK
>NC_008312.1|WP_011612265.1|4205398_4205656_+|2TM-domain-containing-protein
MPPRWPRKPDRNDPEFRKLDDRMNFAIHVATFAASNSGLWFFRNVTAASWPWAIWVTGGWVFLLLIHGLYIFVLADYTTTSKDSG

Crispr_ID: NC_008312_33

• CRISPR_ID: NC_008312_33
• CRISPR_location: 4206483-4206579
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NC_008312_33

Consensus_repeat	Method
TCAGAAATTACGGATATTTTATTGGAAAAGTTT	CRISPRCasFinder

spacers of NC_008312_33

>33.1|4206516|31|NC_008312|CRISPRCasFinder
AAGTTGAGCTAATAAATAATCTGCTGATTTT

CRISPR arrays and Neighbor proteins around NC_008312_33

CRISPR arrays

The CRISPR arrays of NC_008312_33

>merge|NC_008312|33|4206483-4206579|CRISPRCasFinder
TCAGAAATTACGGATATTTTATTGGAAAAGTTTAAGTTGAGCTAATAAATAATCTGCTGATTTTTCAGAAATTACGGATATTTTATTGGAAAAGTTT

>NC_008312|33|27|4206483-4206579|CRISPRCasFinder
TCAGAAATTACGGATATTTTATTGGAAAAGTTT	AAGTTGAGCTAATAAATAATCTGCTGATTTT
TCAGAAATTACGGATATTTTATTGGAAAAGTTT

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_008312.1|WP_011612260.1|4196544_4197528_-|calcium-binding-protein	unknown	unknown	gnl|CDD|380205
NC_008312.1|WP_044136792.1|4211320_4211614_-|hypothetical-protein	unknown	unknown	gnl|CDD|133424
NC_008312.1|WP_011612265.1|4205398_4205656_+|2TM-domain-containing-protein	unknown	unknown	gnl|CDD|379083
NC_008312.1|WP_011612261.1|4199214_4200150_-|hypothetical-protein	unknown	unknown	unknown
NC_008312.1|WP_011612263.1|4203101_4204340_+|MFS-transporter	unknown	unknown	gnl|CDD|341042
NC_008312.1|WP_081432450.1|4210708_4211302_-|sulfotransferase-domain-containing-protein	unknown	unknown	gnl|CDD|366246
NC_008312.1|WP_011612262.1|4201887_4202796_+|hypothetical-protein	unknown	unknown	gnl|CDD|223469
NC_008312.1|WP_011612268.1|4213177_4214185_-|hypothetical-protein	unknown	unknown	unknown
NC_008312.1|WP_011612272.1|4222508_4223261_+|DNA/RNA-nuclease-SfsA	unknown	unknown	gnl|CDD|234733
NC_008312.1|WP_011612273.1|4224521_4225331_+|DNA/RNA-non-specific-endonuclease	unknown	unknown	gnl|CDD|224777
NC_008312.1|WP_011612264.1|4204509_4205010_+|cyclic-pyranopterin-monophosphate-synthase-MoaC	unknown	unknown	gnl|CDD|236483
NC_008312.1|WP_081432451.1|4225652_4225850_-|hypothetical-protein	unknown	unknown	gnl|CDD|369598
NC_008312.1|WP_011612259.1|4192356_4195296_-|DUF563-domain-containing-protein	unknown	unknown	gnl|CDD|368006
NC_008312.1|WP_011612258.1|4187461_4191922_-|tetratricopeptide-repeat-protein	unknown	unknown	gnl|CDD|133027
NC_008312.1|WP_011612267.1|4209105_4210269_-|pyridoxal-phosphate-dependent-aminotransferase	unknown	unknown	gnl|CDD|235596
NC_008312.1|WP_155994417.1|4220714_4221551_+|LPS-biosynthesis-glycosyltransferase	unknown	unknown	unknown
NC_008312.1|WP_011612266.1|4205706_4206015_+|DUF3181-family-protein	unknown	unknown	gnl|CDD|371499
NC_008312.1|WP_011612270.1|4218704_4220324_-|murein-biosynthesis-integral-membrane-protein-MurJ	unknown	unknown	gnl|CDD|240528
NC_008312.1|WP_155994695.1|4186207_4186903_+|pentapeptide-repeat-containing-protein	unknown	unknown	gnl|CDD|224276
NC_008312.1|WP_011612269.1|4214708_4216178_+|DUF4403-family-protein	unknown	unknown	gnl|CDD|379578

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_008312.1|WP_011612260.1|4196544_4197528_-|calcium-binding-protein	gnl|CDD|380205	NF033203, entero_EhxA, enterohemolysin EhxA. Members of this family are the RTX toxin called enterohemolysin or EhxA, because it is found in enterohemorrhagic Escherichia coli (EHEC) strains such as O157:H7.	1.24423e-19
NC_008312.1|WP_044136792.1|4211320_4211614_-|hypothetical-protein	gnl|CDD|133424	cd01339, LDH-like_MDH, L-lactate dehydrogenase-like malate dehydrogenase proteins. Members of this subfamily have an LDH-like structure and an MDH enzymatic activity. Some members, like MJ0490 from Methanococcus jannaschii, exhibit both MDH and LDH activities. Tetrameric MDHs, including those from phototrophic bacteria, are more similar to LDHs than to other MDHs. LDH catalyzes the last step of glycolysis in which pyruvate is converted to L-lactate. MDH is one of the key enzymes in the citric acid cycle, facilitating both the conversion of malate to oxaloacetate and replenishing levels of oxalacetate by reductive carboxylation of pyruvate. The LDH-like MDHs are part of the NAD(P)-binding Rossmann fold superfamily, which includes a wide variety of protein families including the NAD(P)-binding domains of alcohol dehydrogenases, tyrosine-dependent oxidoreductases, glyceraldehyde-3-phosphate dehydrogenases, formate/glycerate dehydrogenases, siroheme synthases, 6-phosphogluconate dehydrogenases, aminoacid dehydrogenases, repressor rex, and NAD-binding potassium channel domains, among others.	0.00438307
NC_008312.1|WP_011612265.1|4205398_4205656_+|2TM-domain-containing-protein	gnl|CDD|379083	pfam13239, 2TM, 2TM domain. This short region contains two transmembrane alpha helices that are found associated with a wide range of other domains. This domain may be involved in cell lysis or peptidoglycan turnover.	1.10127e-07
NC_008312.1|WP_011612263.1|4203101_4204340_+|MFS-transporter	gnl|CDD|341042	cd17489, MFS_YfcJ_like, Escherichia coli YfcJ, YhhS, and similar transporters of the Major Facilitator Superfamily. This subfamily is composed of Escherichia coli membrane proteins, YfcJ and YhhS, Bacillus subtilis uncharacterized MFS-type transporter YwoG, and similar proteins. YfcJ and YhhS are putative arabinose efflux transporters. YhhS has been implicated glyphosate resistance. YfcJ-like arabinose efflux transporters belong to the bacterial MdtG-like and eukaryotic solute carrier 18 (SLC18) family of the Major Facilitator Superfamily (MFS) of transporters. MFS proteins are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	5.46288e-73
NC_008312.1|WP_081432450.1|4210708_4211302_-|sulfotransferase-domain-containing-protein	gnl|CDD|366246	pfam00685, Sulfotransfer_1, Sulfotransferase domain.	1.03492e-45
NC_008312.1|WP_011612262.1|4201887_4202796_+|hypothetical-protein	gnl|CDD|223469	COG0392, COG0392, Predicted integral membrane protein [Function unknown].	2.64218e-05
NC_008312.1|WP_081432451.1|4225652_4225850_-|hypothetical-protein	gnl|CDD|369598	pfam07924, NuiA, Nuclease A inhibitor-like protein. This family consists of protein sequences that are similar to the nuclease A inhibitor expressed by bacteria of the genus Anabaena ((NuiA). This sequence is organized to form an alpha-beta-alpha sandwich fold, which is similar to the PR-1-like fold. NuiA interacts with nuclease A by means of residues located at one end of the molecule, including residues making up the loop between helices III and IV and the loop between strands C and D. The mechanism of inhibition of nuclease A by NuiA is as yet incompletely understood.	3.92575e-19
NC_008312.1|WP_011612272.1|4222508_4223261_+|DNA/RNA-nuclease-SfsA	gnl|CDD|234733	PRK00347, PRK00347, DNA/RNA nuclease SfsA.	1.72152e-116
NC_008312.1|WP_011612264.1|4204509_4205010_+|cyclic-pyranopterin-monophosphate-synthase-MoaC	gnl|CDD|236483	PRK09364, moaC, cyclic pyranopterin monophosphate synthase MoaC.	4.32866e-93
NC_008312.1|WP_011612259.1|4192356_4195296_-|DUF563-domain-containing-protein	gnl|CDD|368006	pfam04577, DUF563, Protein of unknown function (DUF563). Family of uncharacterized proteins.	6.27357e-57
NC_008312.1|WP_011612258.1|4187461_4191922_-|tetratricopeptide-repeat-protein	gnl|CDD|133027	cd04184, GT2_RfbC_Mx_like, Myxococcus xanthus RfbC like proteins are required for O-antigen biosynthesis. The rfbC gene encodes a predicted protein of 1,276 amino acids, which is required for O-antigen biosynthesis in Myxococcus xanthus. It is a subfamily of Glycosyltransferase Family GT2, which includes diverse families of glycosyl transferases with a common GT-A type structural fold, which has two tightly associated beta/alpha/beta domains that tend to form a continuous central sheet of at least eight beta-strands. These are enzymes that catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds.	1.27272e-78
NC_008312.1|WP_011612267.1|4209105_4210269_-|pyridoxal-phosphate-dependent-aminotransferase	gnl|CDD|235596	PRK05764, PRK05764, aspartate aminotransferase; Provisional.	0
NC_008312.1|WP_011612273.1|4224521_4225331_+|DNA/RNA-non-specific-endonuclease	gnl|CDD|224777	COG1864, NUC1, DNA/RNA endonuclease G, NUC1 [Nucleotide transport and metabolism].	7.18374e-74
NC_008312.1|WP_011612266.1|4205706_4206015_+|DUF3181-family-protein	gnl|CDD|371499	pfam11378, DUF3181, Protein of unknown function (DUF3181). This family of proteins has no known function.	1.06884e-43
NC_008312.1|WP_011612270.1|4218704_4220324_-|murein-biosynthesis-integral-membrane-protein-MurJ	gnl|CDD|240528	cd13123, MATE_MurJ_like, MurJ/MviN, a subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins. Escherichia coli MurJ (MviN) has been identified as essential for murein biosynthesis. It has been suggested that MurJ functions as the peptidoglycan lipid II flippase which is involved in translocation of lipid-anchored peptidoglycan precursors across the cytoplasmic membrane, though results obtained in Bacillus subtilis seem to indicate that its MurJ homologs are not essential for growth. Some MviN family members (e.g. in Mycobacterium tuberculosis) possess an extended C-terminal region that contains an intracellular pseudo-kinase domain and an extracellular domain resembling carbohydrate-binding proteins. Proteins from the MATE family are involved in exporting metabolites across the cell membrane and are often responsible for multidrug resistance (MDR).	2.93672e-106
NC_008312.1|WP_155994695.1|4186207_4186903_+|pentapeptide-repeat-containing-protein	gnl|CDD|224276	COG1357, COG1357, Pentapeptide repeats containing protein [Function unknown].	1.80471e-27
NC_008312.1|WP_011612269.1|4214708_4216178_+|DUF4403-family-protein	gnl|CDD|379578	pfam14356, DUF4403, Domain of unknown function (DUF4403). This family of proteins is functionally uncharacterized. This family of proteins is found in bacteria. Proteins in this family are typically between 455 and 518 amino acids in length. There is a single completely conserved residue W that may be functionally important.	8.4024e-93

Protein sequences

>NC_008312.1|WP_011612266.1|4205706_4206015_+|DUF3181-family-protein
MANGSTTQIIESLAAEIGDKVYMDITGWHLYLSDAKLHLNLAEKFYPILTEEVPSEAQVMEILQGVPVKLGAGRKQVPLIDLLPIHCQSDLMEVLAEFRENI
>NC_008312.1|WP_011612265.1|4205398_4205656_+|2TM-domain-containing-protein
MPPRWPRKPDRNDPEFRKLDDRMNFAIHVATFAASNSGLWFFRNVTAASWPWAIWVTGGWVFLLLIHGLYIFVLADYTTTSKDSG
>NC_008312.1|WP_011612264.1|4204509_4205010_+|cyclic-pyranopterin-monophosphate-synthase-MoaC
MTRDFSKFEQNLTHLDSEGAVKMVDVSTKVQTIRQAEAAGQVRMLPETFEAIQRGNSPKGDVLGTAKLAGIMAAKQTAQLIPLCHPLPLQKIDIELIPDPHLPGYQIRAMVKTKAETGVEMEALTAVSVAALTLYDMAKALEKSISIELIRLLSKSGGKSGDYMVK
>NC_008312.1|WP_011612263.1|4203101_4204340_+|MFS-transporter
MKVFKTLDPKQQRSLMILFLAGLLFWSSITTLLPTLPLYLNYIGGTKQQIGFVLGCFSMGLLLSRFILAPIADTKSRKLVLIVGTSVAAIAPLGYLLFKSFLFLMLVRAFHGISIAGVTIGYTALVADLSPPGRRGELIGYMSLCTPIGMAIGPTVGGFLVEANEYVPLFIVCSTLGIASLLFSILVSESSAIAQKNLHSHQFEQQKLWQILGSRRVLVPVFVMLIVGLIFGTTTTFLPLYIQENSIALNAGIFYTVRGITNLLIRIFTGRASDKFGRGVFISSGLVFSLLGMLTLWTANSRNMILLAAILGGSSSGLILPMMITLMTDRCPPDQRGKFFSLCIGGFDVGIAIAGPTFGLVAEQIGYRSMFAIDAILASIAIATFITLSNSNLPHSIRFAFGRGQDTYAINH
>NC_008312.1|WP_011612262.1|4201887_4202796_+|hypothetical-protein
MKKVLSDIKPYLRWIILGATLFFLVKTLKDNWEQVLQIRISDSGWISLGTAFLITIMAHVWSGWVWFWIIKEFNQLVNFPWAIRVYLLTNIAKYLPGNIWHFYGRITEVKKVGVPIEIAILSVLIEPLLMAAAALIVALVGSTQESFFLQLFCFFSVICIIHPRILNPIIKCLVKIKLKFKKIDLEPDNELVLERYPIKPFVGEVCFVLLRGSGFLLTILAFNSIEFNQILLIFSAFSFAWLLGLVVPGAPGGVGVFEATALALLEQKFAPGIVLSAVAFYRLISVLAETFAAGLAWLKQKI
>NC_008312.1|WP_011612261.1|4199214_4200150_-|hypothetical-protein
MTFFNKDEQLNILGKDIIEATQLEFSELTSEAIAITWLVYNSPITRNIQNATEFWQKQVRGWSDRGDEKMYAGGMVHLFYLVAIYEWLEKGMVKTSPELERAIRDMILSANHDGTSLVVDVLTGTTSGPELSPGPFQTWKYQRNFINRYFQSLKWPELKSINVNQKTWFYGPYGRERIFQGLLMENRNILTTNATARLLHSIVGGIAVSRQASGKIMDLLQKNLSQQDAKYVTKSQTIGFLKESLPQNAKIWSREIVDTHVHHNFAYIELPNLLPYLLVIFTEGKEISKNERILPYISQKFVEAMKKLSLK
>NC_008312.1|WP_011612260.1|4196544_4197528_-|calcium-binding-protein
MTSLIDGNINDLINNIPEEEQPDGGFDTLPTVDRPIEGGDGGRDIQGGPTADAIEGSTASDVVSTGAGDDLVAAGDGDDDVLLGTGDDTVLAGTGVDTISGNQGNDSVAGGAGDDLLYGGKGDDSVEGGEGADFVFGDRGSDLVQGGAGDDVALGGRDSDTVTGDEGNDTLDGGKGDDILSGGVGDDFLFGGKGSDTLTGGTGADKFLFYYNEDGSYGLDSLTDFNRDQGDKIGIVVNNFGGGNFEALTGARPGDSLSGAQFAVVENFSPNEDGANSAAIIYDPDTGLVYYNPDGSAVAGNETPIARVDNTVFDSNNPLQGTDFEIF
>NC_008312.1|WP_011612259.1|4192356_4195296_-|DUF563-domain-containing-protein
MKIEKYLRLAKSYLTKGNLSQAIEICEQILEIQPNSAHAYRILGEIYQAEENFEKAMYAYTKAVEIQPKYAEVHAFLAWLYSQKKWLSEAANQYQKAINLGLKWPELYYNLGNIFYQVRYFESAIQCYENAIVIKPNYINAYLGLGIIFERERNYQAAVDIYRKVIELNPDFVEGYNNLGRILANWNRRSEAIEVYQQALVLKPDSASLYNNLGFTLLNENPIEAIAAYYRAIELDPLLIKAHYNLGKALQIIGEHELAVKSFQEVIRLKGKKDNLLVYSDCAFSLMTIGKFQTAFVYLKNVITNNKFVDGCWQVLESKLGNLEHIEYDKMYLTKVAVLNFIKELKKLDINSENYQQSSQKISRYLLSYYINFGNVLMENEFYKSAENIYHKALKIKPNSADIYWLLGNNLAKQKRLNSAIISYQIALQILLNENRINQTTKIYFELGKIMEKQQRWQAARDYYSKVLSGKVEDILNNDFNNDFLPYPKLEGLYLSTKDWLQKLDGNNYQKRYKEVRLEKLATEYREESIKSPIKVSVENKKKDLECLGLNCSACLKQIYQWFDPKSPAQGIYSLRDQGEFSQDIDLLSQEISLLNPLEKEGKKSLTPGKNERMSPSSLTSVSKEESILSLTKDTKNDKEGLSYFQKLSRSPTFVTTVPEGRAWIMPKKNYWRLCYGIAIMTPDNYLLSDLSREYPSPLPGCTKHDPSQHRIFGFEELPPLEKINGKVAVLSVLSGNVYFHWMVDLLPRIEILRQGINLEEIDWFIVNDYQQPFQRETLKTLGVKQEKILASDRHPHVQATELVVPSYPSYLGWLQPWGLKFLREVFLRGITNNKSYFPEKIYIGRGNAKYRRVMNEAEVVDILRQFGFTYVTPESISLENQISTFAHAKIIVAPHGSGLTNIVFCNPGTKVIELFSPHYLRYYYWHISQLLGLEHYYLIGETFSCYPMRNIMYESSLVEDILVNLDSLNQMLKVVDIF
>NC_008312.1|WP_011612258.1|4187461_4191922_-|tetratricopeptide-repeat-protein
MASINPQETAAENFHKKAEAYLAEKKFDEAIASCELAIKIEDNYFPAYKTLGNTWQAQGKLAEAENWYKKALEIKSNWPEIYANLGSLYAMQQKWEEAISYYQKAVDIKPDFAGAYRNMRKVWLSLGNQKLATYCQYKVLSIEPEKATFEEFMNVGKTLEKEGSLNDAISCYRMATKLNSNSSEAYQNLGEALKEQGNLDEATVCCRKAIELKVNGKKIENSDDTLGAASKYNLISSQELNSGDTLVGSLSSNKVNGHNTLVRATIPTTSPTVNAEDIETYMVEAETYVNQKKWEQAIAVSKQVIQTKTEPKAYKIIGNSLQAMGKLQEALDWYNKALKIKPDFGEVYANIGTIFAQQKQWGQAIQNYLRAIEIKPEFAGAYRNLAKIYTQVNKSQEAAEYLYQAIRLEPGKATAQDFLFTGNTLSENGKLEQAIACYQQLISADPNSFEAYEKLGDSLLKQGQLELSLQNYKNAQKLKPYSTEIKQKIGEIYYRYGEYFQKKEKVEEAVKAYRQAIENYPQYDIPYGKLGEVFSQQEKWEEAVKVYEKASQIKPDNSWYYNSLGEALKKLEKWEEAVMAYRKAIQLNPDFSWSHNNLADCLVKLGKREEAVVAYRQAIKLKPDFTWSYINLGNTLWEIGNWQEAINPYSRALELKADLPETYQKLGHALKKRAELDLEESIKWYRKAIENDPDNEKLYHKALEVKPEDHTLYLQLGNTLVKKGKTHGAIAFYQLGLQINPDDSEIQGQLEKILPKKNTLREKKKDNRKKNKVPIFPLPSSPVIEKNEEKKVPISPLPSSPVIEKEDTYQLWLKENLPNSDQLKKMSENLKIFRYQPLISIILQEKSGSPYIQKTIESLINQIYPNWELCYISDKLPQNIEANNKIKLVIKSENRDIATDLNAALALATGDFVTLLNPEDILTPDALYEMVLFLNRYPDSDMIYSDEDKLTSEGKLIEPYFKPNWSPDSFLSRMYTGHLCIYRRELLEKLNGFRVGYESSYEYDLILRLSEVSQKIFHIPKVLYHSRIPENGGEIDWEISKETTKKTLTEALARRGEMGTVYSVPNHPGFYRVRYQISEQKLVSIIIPTRNLGNILDRCLESIFTQTTYPNYEVIVIDNGSDEPETLSIIEKWKNQQPERFKCYEKNIPFNFSKLNNYAVEKAEGDYLLFLNNDTEVKTADWLEAMVEQAQRETIGAVGALLLYPDNTIQHAGVVLGMRSVADHSHRGFSPTDAGYKGQIISVNNYSAVTAACLMCRREVFEQVGGFDEELAVAFNDVDLCLKIIYKGYRNIYLPHAVLYHHESKSRGVENTGEKQLRFQQEIQNMKQRWKDLIDEDPCYHPHLTRQQEDFSLRVQTNVEVALSMYDKDPEIVGCSIDVPSPGVKQNISSICIGGWVVGKKSSPVTVKLISLTKSGKVLREVPANLHRPDVGKIHPEYPYAQHSGFWGEIEVIEIAPESKISLEAIFKDGSHVRLGMVSFKCPNLI
>NC_008312.1|WP_155994695.1|4186207_4186903_+|pentapeptide-repeat-containing-protein
MKITLAMKFLATVTFVISFIYLSLSAPIMGANYEDVNHLLEYNWCVSFLWKQCDLTRANFHDINLKNANMSGANLTGVNFQGADLNGANLSGANLTGANLEKANLYRADINRANLTNTNLTSTRLLEADLTLANLNHANLTDANLLEARLWGASLAGANLNNASLHGTNLEYANLADSNLSGADFHSFSFRSYKQETNLSNANLEGAIITNTDLSGVIMRGTIMPDGSINE
>NC_008312.1|WP_011612267.1|4209105_4210269_-|pyridoxal-phosphate-dependent-aminotransferase
MNFATRMNSLGGDAAIEVFTKAKQLESQGRNIIHLEIGQPDFKTPKNIREAAFQAMNDGYTTYTPAAGLLKLREVIAEHISQTRNISVNSDEVVVMPGAKPVIFFTLLALINSGDEVIYPNPGFPVYESVINLVGGKPIPLPLLEELDFQFSIDNLVNSISEKTKLLIINSPHNPTGSVLTPEYLEAIAKLAVKHNFYVLSDEIYSHLNYDSKFTSIISFPSMKERTILLDGHSKTYAMTGWRLGYSISPKAIAEKLDKLMLNSNSCACSFTQIAGIEAIKNSQEFVKKIFAEFKQRRDVIVDGLNSISGINCRKPAGAFYAFPNVKQLPISSNKLADYLLAEAGVALLPGTAYGKFGDGYLRLSYANSIENIREGISRIETAIAKL
>NC_008312.1|WP_081432450.1|4210708_4211302_-|sulfotransferase-domain-containing-protein
MLTFYGRPHLTPEGLPNTKYIFLLRNPKDVAVSMYHHLRRKKSISYQDNWNDFFELYLSGQVHYGSWFDFHLHWEKFLPSRQQVLYLTYEELKKNIKTCLSQLAAFLEIKVSAEVIDKVAIDSKLEEMKKNDKADCNWMRINQNEAPHLRKGIVGDWRNYFTEEQNQHFNDLYIKKMSGSKFKDYWDESILGITRED
>NC_008312.1|WP_044136792.1|4211320_4211614_-|hypothetical-protein
MKTQNSSWYSIVDGIVYPQFVTEEKVNTILTRFKTRNEDIFFVCYIKSGSTWLKQILLLLNHQGNQPNLNMMEAFSRLEFCLSPCLEPAQKRSYEYI
>NC_008312.1|WP_011612268.1|4213177_4214185_-|hypothetical-protein
MTKETFDFVIPLYKVRWNTQAVLEGISHHYKPQTIHIIAPKTEVQLLEQKVKEWQVAPVSAHKEEYFFQNHGLTKEAICSELDLGKSLYNPGWFYQQLLKLGAYEGIDNLSEWFVVWDSDLLPVNTWPLISNHQETTQHKFALLQHNQYGNPHIVSKWAEWITSVLGVEPLTDQEGTFVPHHMWFKKEHLESFKNQVKSYFQSQENWLLLMMRSANQFETFSEYWSYISWVAAKAPADLAFYPYENYGATTERFFDDGTGLFSAALRNYQSKISDGAPFSVSYKEIELFIKEKYESDSLPSSLSFESNPRHLKKDRKNMHIEEICSRWNPRQSEV
>NC_008312.1|WP_011612269.1|4214708_4216178_+|DUF4403-family-protein
MKIFFIPRIIFFFILMIFVLIVITFSSMATFTGIDIQPKRLELMLANILESERSESTLSLPVKIPLANVEKALNLNIPQTFMGTEADPIDLLSNDKLTYKINRQDLIIGTRNNLITFSVPVSGTARIKGKVDLGFTSIPVSTRTDIVGTIFGDLALGIDNEWNIQPNLNVRTNLTKADVPIKNIGTISIRSILQKQVDKAINKEKPKLIAKLVEKLNLKAEVTKQWNNLHLSEKVNQDPSIWIKTEPQSVSFKEFDLTDGKNVQSGIGIRMLVDTCICKEALAINFKPLPNLTIQEQIINKFLINLPVQVSLDELNNTLRSKVRGNSLSIDENLKLIVKEINLSALGEKILVKVDFKADKNSFLQEAEGVLYLWGNIFYDQASNYLKVVELDYDVDTKNALILTADLLLKPILLRKIEERLSFPLDQQLSRAKDEANEYIRKIKLPPEIDANIVVKTIKVQKVVVTNNDIYLVLLADGNMSAILNIGEY
>NC_008312.1|WP_011612270.1|4218704_4220324_-|murein-biosynthesis-integral-membrane-protein-MurJ
MSESKSQKNSRSLTKIAGIVAVATLISKIFGLIRQQAIAAAFGVGAAVDAYNYAYVIPGFLLVLLGGINGPFHSAIVSVLAKRDKSEAAPLIETITTLVSGVLLLVTVSLIFFADPLIDLVAPGLSQTTTGLKIRAIAIQQFQIMAPMALLAGLIGIGFGALNAADIYWLPSISPLFSSIALIGGIFILVFQLGENITQPEHAMIGGIILAWSTLIGAILQWLIQVPSLWRAGLGKLRFRFNFRNPGVQEITKVMIPATLSSGMLHINVYTDLFFASYIPQAAASLGYSGLLVQTPLGIISNVILVPFLPIFSRLAAPENWQDLKYRIRQALVLTGITMLPLSAIMVTLALPIVRVVYERYAFDLSASKFVASVLIAYAVGMFVYLGRDVLVRVFYALGDGETPFKVSVFNIFLNALLDYLLINTFGAPGLVLATVGVNLISMVIFLWLLDQKLGGLPWGEWLIPFAGLILGTLAASFVCWSVLYGCQLVLGSEGFFVQLLELGLASFSALGIFGLIVMKMNLPEVDIFISRIRQKLRI
>NC_008312.1|WP_155994417.1|4220714_4221551_+|LPS-biosynthesis-glycosyltransferase
MSNKNSLKCSISGVFIIAYKEDTTILEKTLQEQGFNYELLRQKYEPEYKSYSPSYLTLLNHKNAWIKASEEEKSSLIIEADFVPVINFGLLPLPFNLENYNVGIAWLYTCAPQIYSVSDENYAQGFSTSAVAYIVTPRSALELIELENEVRLNSGTNNYSTWDSTIDEFLRGRGFQNFVPFRNYGEHGGLPNLEHYRYGLSRVHRADILYDRLAFMPIYAGRDKFKIWRLFRERFQGRLKGILRLLFGKYLRLKIIRNSSFPLRLIRFAVWRQLFLRI
>NC_008312.1|WP_011612272.1|4222508_4223261_+|DNA/RNA-nuclease-SfsA
MICYPIIMNNQLKFSYKYPSLEPGILIKRYKRFLADIELKSGGIITAHCPNTGPMTGVSTPGSNVMVSYSNNPKRKLAYTWELIEVTDNEPTWVGINTALPNRVIKLALAENLFPELGDYYEVKTEVVYGKDRKSRVDFKLISETKNIYLEVKNTTWADGRVALFPDTVTKRGQKHLRELIGVVEQGERAVCLFLINRGDCYQFAPGDVADHDYGKLLREAMIKGVEILPCRFIVTPQEINYLGIAEFIN
>NC_008312.1|WP_011612273.1|4224521_4225331_+|DNA/RNA-non-specific-endonuclease
MLILPRKINLGIIIILLTFSSGCSLFLKPSPKVHITLGNPSNATTNMENSDNYLIEKSQYVLSYNRNKGIANWVSWQLNKSWLGYVERQDDFRPDESLPEDWYHVKTNNYINSGYDRGHLIPSADRTANENDNSATFLMTNIIPQSPNNNRETWRELEEYSRELVKAGNELYIIAGGYRKKGNIAGGKVTIPSRLWKVIVVLKSGVGVRGVDKNTRVIAVDMPNSNRIRSDWKAYRVSVDKIESSTGYDFLSKVPKEIQDVIESRVDNR
>NC_008312.1|WP_081432451.1|4225652_4225850_-|hypothetical-protein
MILTFRYNSKEYERVKRYQKNVKKMQQYLSDLKVYKVGRIEIYIDIIGRTNTGNYAGLATVYIET

Crispr_ID: NC_008312_34

• CRISPR_ID: NC_008312_34
• CRISPR_location: 4303513-4303584
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NC_008312_34

Consensus_repeat	Method
TTTCCACTCATACCTGTTACACT	CRISPRCasFinder

spacers of NC_008312_34

>34.1|4303536|26|NC_008312|CRISPRCasFinder
GGATATAAAGTTTGGCGTGACAAAGG

CRISPR arrays and Neighbor proteins around NC_008312_34

CRISPR arrays

The CRISPR arrays of NC_008312_34

>merge|NC_008312|34|4303513-4303584|CRISPRCasFinder
TTTCCACTCATACCTGTTACACTGGATATAAAGTTTGGCGTGACAAAGGTTTCCACTCATACCTGTTACAGT

>NC_008312|34|28|4303513-4303584|CRISPRCasFinder
TTTCCACTCATACCTGTTACACT	GGATATAAAGTTTGGCGTGACAAAGG
TTTCCACTCATACCTGTTACAGT

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_008312.1|WP_011612320.1|4307060_4311179_-|glycerophosphoryl-diester-phosphodiesterase	unknown	unknown	gnl|CDD|176544
NC_008312.1|WP_011612308.1|4283569_4284199_+|type-I-restriction-endonuclease-subunit-R	unknown	unknown	gnl|CDD|335717
NC_008312.1|WP_011612324.1|4316787_4317432_-|cobalt-transporter-CbiM	unknown	unknown	gnl|CDD|235760
NC_008312.1|WP_044137537.1|4313546_4314593_+|ion-transporter	unknown	unknown	gnl|CDD|366146
NC_008312.1|WP_155994421.1|4289907_4290909_-|hypothetical-protein	unknown	unknown	unknown
NC_008312.1|WP_011612313.1|4291520_4294466_-|ABC-transporter-substrate-binding-protein	unknown	unknown	gnl|CDD|380492
NC_008312.1|WP_011612323.1|4315772_4316561_-|cobalt-ECF-transporter-T-component-CbiQ	unknown	unknown	gnl|CDD|274139
NC_008312.1|WP_011612325.1|4317525_4318032_-|carboxypeptidase-regulatory-like-domain-containing-protein	unknown	unknown	gnl|CDD|379297
NC_008312.1|WP_011612316.1|4299818_4301165_-|cytochrome-P450	unknown	unknown	gnl|CDD|365848
NC_008312.1|WP_011612315.1|4296675_4298742_-|elongation-factor-G	unknown	unknown	gnl|CDD|237186
NC_008312.1|WP_044136808.1|4306233_4306575_+|CHAT-domain-containing-protein	unknown	unknown	gnl|CDD|227328
NC_008312.1|WP_011612318.1|4303654_4305139_+|insulinase-family-protein	unknown	unknown	gnl|CDD|223685
NC_008312.1|WP_011612322.1|4314811_4315546_-|energy-coupling-factor-ABC-transporter-ATP-binding-protein	unknown	unknown	gnl|CDD|213192
NC_008312.1|WP_011612326.1|4318431_4319469_+|IS630-family-transposase	unknown	unknown	gnl|CDD|315923
NC_008312.1|WP_011612314.1|4294716_4296081_-|DUF1800-domain-containing-protein	unknown	unknown	gnl|CDD|378055
NC_008312.1|WP_044136805.1|4288975_4289923_-|MoxR-family-ATPase	unknown	unknown	gnl|CDD|223786
NC_008312.1|WP_155994423.1|4319924_4320782_-|DUF4382-domain-containing-protein	unknown	unknown	unknown
NC_008312.1|WP_011612310.1|4287743_4288979_-|hypothetical-protein	unknown	unknown	gnl|CDD|226346
NC_008312.1|WP_155994422.1|4301647_4303120_+|insulinase-family-protein	unknown	unknown	gnl|CDD|223685
NC_008312.1|WP_081432547.1|4284495_4287171_-|tetratricopeptide-repeat-protein	unknown	unknown	gnl|CDD|276809

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_008312.1|WP_011612320.1|4307060_4311179_-|glycerophosphoryl-diester-phosphodiesterase	gnl|CDD|176544	cd08602, GDPD_ScGlpQ1_like, Glycerophosphodiester phosphodiesterase domain of Streptomycin coelicolor (GlpQ1) and similar proteins. This subfamily corresponds to the glycerophosphodiester phosphodiesterase domain (GDPD) present in a group of putative bacterial and eukaryotic glycerophosphodiester phosphodiesterases (GP-GDE, EC 3.1.4.46) similar to Escherichia coli periplasmic phosphodiesterase GlpQ, as well as plant glycerophosphodiester phosphodiesterases (GP-PDEs), all of which catalyzes the Ca2+-dependent degradation of periplasmic glycerophosphodiesters to produce sn-glycerol-3-phosphate (G3P) and the corresponding alcohols. The prototypes of this family include putative secreted phosphodiesterase encoded by gene glpQ1 (SCO1565) from the pho regulon in Streptomyces coelicolor genome, and in plants, two distinct Arabidopsis thaliana genes, AT5G08030 and AT1G74210, coding putative GP-PDEs from the cell walls and vacuoles, respectively.	3.60498e-110
NC_008312.1|WP_011612308.1|4283569_4284199_+|type-I-restriction-endonuclease-subunit-R	gnl|CDD|335717	pfam04313, HSDR_N, Type I restriction enzyme R protein N-terminus (HSDR_N). This family consists of a number of N terminal regions found in type I restriction enzyme R (HSDR) proteins. Restriction and modification (R/M) systems are found in a wide variety of prokaryotes and are thought to protect the host bacterium from the uptake of foreign DNA. Type I restriction and modification systems are encoded by three genes: hsdR, hsdM, and hsdS. The three polypeptides, HsdR, HsdM, and HsdS, often assemble to give an enzyme (R2M2S1) that modifies hemimethylated DNA and restricts unmethylated DNA.	0.00086576
NC_008312.1|WP_011612324.1|4316787_4317432_-|cobalt-transporter-CbiM	gnl|CDD|235760	PRK06265, PRK06265, cobalt transporter CbiM.	5.17597e-67
NC_008312.1|WP_011612318.1|4303654_4305139_+|insulinase-family-protein	gnl|CDD|223685	COG0612, PqqL, Predicted Zn-dependent peptidases [General function prediction only].	1.57235e-102
NC_008312.1|WP_044137537.1|4313546_4314593_+|ion-transporter	gnl|CDD|366146	pfam00520, Ion_trans, Ion transport protein. This family contains sodium, potassium and calcium ion channels. This family is 6 transmembrane helices in which the last two helices flank a loop which determines ion selectivity. In some sub-families (e.g. Na channels) the domain is repeated four times, whereas in others (e.g. K channels) the protein forms as a tetramer in the membrane.	1.1384e-22
NC_008312.1|WP_011612313.1|4291520_4294466_-|ABC-transporter-substrate-binding-protein	gnl|CDD|380492	cd06268, PBP1_ABC_transporter_LIVBP-like, periplasmic binding domain of ATP-binding cassette transporter-like systems that belong to the type 1 periplasmic binding fold protein superfamily. Periplasmic binding domain of ATP-binding cassette transporter-like systems that belong to the type 1 periplasmic binding fold protein superfamily. They are mostly present in archaea and eubacteria, and are primarily involved in scavenging solutes from the environment. ABC-type transporters couple ATP hydrolysis with the uptake and efflux of a wide range of substrates across bacterial membranes, including amino acids, peptides, lipids and sterols, and various drugs. These systems are comprised of transmembrane domains, nucleotide binding domains, and in most bacterial uptake systems, periplasmic binding proteins (PBPs) which transfer the ligand to the extracellular gate of the transmembrane domains. These PBPs bind their substrates selectively and with high affinity. Members of this group include ABC-type Leucine-Isoleucine-Valine-Binding Proteins (LIVBP), which are homologous to the aliphatic amidase transcriptional repressor, AmiC, of Pseudomonas aeruginosa. The uncharacterized periplasmic components of various ABC-type transport systems are included in this group.	2.29368e-59
NC_008312.1|WP_011612323.1|4315772_4316561_-|cobalt-ECF-transporter-T-component-CbiQ	gnl|CDD|274139	TIGR02454, Uncharacterized_protein_MJ1089, cobalt ECF transporter T component CbiQ. This model represents the CbiQ component of the cobalt-specific ECF-type. CbiQ is now recognized as the T component of energy-coupling factor (ECF)-type transporters. The S component confers specificity (CbiM-N for cobalt systems), which CbiO is the ABC-family ATPase. In general, proteins found by this model reside next to the other putative subunits of the complex, identified as CbiN, CbiO, or CbiM. Note that the designation of cobalt transporter has been spread excessively among ECF system transporters with many other specificities. [Transport and binding proteins, Cations and iron carrying compounds].	1.67774e-32
NC_008312.1|WP_011612325.1|4317525_4318032_-|carboxypeptidase-regulatory-like-domain-containing-protein	gnl|CDD|379297	pfam13620, CarboxypepD_reg, Carboxypeptidase regulatory-like domain.	0.000232462
NC_008312.1|WP_011612316.1|4299818_4301165_-|cytochrome-P450	gnl|CDD|365848	pfam00067, p450, Cytochrome P450. Cytochrome P450s are haem-thiolate proteins involved in the oxidative degradation of various compounds. They are particularly well known for their role in the degradation of environmental toxins and mutagens. They can be divided into 4 classes, according to the method by which electrons from NAD(P)H are delivered to the catalytic site. Sequence conservation is relatively low within the family - there are only 3 absolutely conserved residues - but their general topography and structural fold are highly conserved. The conserved core is composed of a coil termed the 'meander', a four-helix bundle, helices J and K, and two sets of beta-sheets. These constitute the haem-binding loop (with an absolutely conserved cysteine that serves as the 5th ligand for the haem iron), the proton-transfer groove and the absolutely conserved EXXR motif in helix K. While prokaryotic P450s are soluble proteins, most eukaryotic P450s are associated with microsomal membranes. their general enzymatic function is to catalyze regiospecific and stereospecific oxidation of non-activated hydrocarbons at physiological temperatures.	2.19242e-62
NC_008312.1|WP_011612315.1|4296675_4298742_-|elongation-factor-G	gnl|CDD|237186	PRK12740, PRK12740, elongation factor G-like protein EF-G2.	0
NC_008312.1|WP_044136808.1|4306233_4306575_+|CHAT-domain-containing-protein	gnl|CDD|227328	COG4995, COG4995, Uncharacterized protein conserved in bacteria [Function unknown].	2.26145e-13
NC_008312.1|WP_011612322.1|4314811_4315546_-|energy-coupling-factor-ABC-transporter-ATP-binding-protein	gnl|CDD|213192	cd03225, ABC_cobalt_CbiO_domain1, First domain of the ATP-binding cassette component of cobalt transport system. Domain I of the ABC component of a cobalt transport family found in bacteria, archaea, and eukaryota. The transition metal cobalt is an essential component of many enzymes and must be transported into cells in appropriate amounts when needed. This ABC transport system of the CbiMNQO family is involved in cobalt transport in association with the cobalamin (vitamin B12) biosynthetic pathways. Most of cobalt (Cbi) transport systems possess a separate CbiN component, the cobalt-binding periplasmic protein, and they are encoded by the conserved gene cluster cbiMNQO. Both the CbiM and CbiQ proteins are integral cytoplasmic membrane proteins, and the CbiO protein has the linker peptide and the Walker A and B motifs commonly found in the ATPase components of the ABC-type transport systems.	4.03184e-83
NC_008312.1|WP_011612326.1|4318431_4319469_+|IS630-family-transposase	gnl|CDD|315923	pfam13358, DDE_3, DDE superfamily endonuclease. This family of proteins are related to pfam00665 and are probably endonucleases of the DDE superfamily. Transposase proteins are necessary for efficient DNA transposition. This domain is a member of the DDE superfamily, which contain three carboxylate residues that are believed to be responsible for coordinating metal ions needed for catalysis. The catalytic activity of this enzyme involves DNA cleavage at a specific site followed by a strand transfer reaction.	1.06945e-33
NC_008312.1|WP_011612314.1|4294716_4296081_-|DUF1800-domain-containing-protein	gnl|CDD|378055	pfam08811, DUF1800, Protein of unknown function (DUF1800). This is a family of large bacterial proteins of unknown function.	1.37322e-173
NC_008312.1|WP_044136805.1|4288975_4289923_-|MoxR-family-ATPase	gnl|CDD|223786	COG0714, COG0714, MoxR-like ATPases [General function prediction only].	2.07389e-35
NC_008312.1|WP_011612310.1|4287743_4288979_-|hypothetical-protein	gnl|CDD|226346	COG3825, COG3825, Uncharacterized protein conserved in bacteria [Function unknown].	3.71468e-19
NC_008312.1|WP_155994422.1|4301647_4303120_+|insulinase-family-protein	gnl|CDD|223685	COG0612, PqqL, Predicted Zn-dependent peptidases [General function prediction only].	5.77119e-91
NC_008312.1|WP_081432547.1|4284495_4287171_-|tetratricopeptide-repeat-protein	gnl|CDD|276809	sd00006, TPR, Tetratricopeptide repeat. The Tetratricopeptide repeat (TPR) typically contains 34 amino acids and is found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi, plants, and humans. It is present in a variety of proteins including those involved in chaperone, cell-cycle, transcription, and protein transport complexes. The number of TPR motifs varies among proteins. Those containing 5-6 tandem repeats generate a right-handed helical structure with an amphipathic channel that is thought to accommodate an alpha-helix of a target protein. It has been proposed that TPR proteins preferentially interact with WD-40 repeat proteins, but in many instances several TPR-proteins seem to aggregate to multi-protein complexes.	2.34075e-06

Protein sequences

>NC_008312.1|WP_155994422.1|4301647_4303120_+|insulinase-family-protein
MMAIAREYQSSGEISIKPYLDRVIKKVTEFRLNNGMKFIVLERHSAPVISFVIYADVGGANEPDGKTGVAHYLEHLAFKGTKKIGTKDYEAEKPILDNLDRIFAQIQQSKIDGKTEEVAKLKADFEKAQNLASEYVNQNEFSKIVQQAGGVGLNAATSADYTQYFYSLPANKLELWMSLESERFLEPVFREFYKEKQVILEERRSRTENSPVAQILEEFLRKAFLVHPYGRPIIGYSKEIQNLTRENVRNFFDLHYVPSNLNVAIVGDVNPKEVKKLAKIYFGRYKVKQKPPRLNVVEPTQAETREVTMELPSQPWYIEGYHRPAMNHPDSVIYDMITSILSDGRTSRLYQSLVEKQQVALVARGFSGYPGSKYPHLILFYAMTAPNSNIDEVGAALQAEIERLKTELVSEQELQRVKTQARAGMLRSLDSNMGMASALLDYEVKTGSWQNLFKELDIINAVTREDIQRIAQKTFVPENRTIARLLSKQN
>NC_008312.1|WP_011612316.1|4299818_4301165_-|cytochrome-P450
MNMNFKSSNPASSLALPPGDLGLPFIGQNKKIFKNPQNFIEEVYQKYGPVYKTNFLGKNFIYFQGYEAIKFILTNENKYFTYSQILRNYQRIFGENDITVLAGKEHRERQKILAKTIKSKNLNNYIDIIHDLSQSYFLKWIKSDYVDLYSEINNYTLDMILKLLLGIDYASKSEISNYLKDMSSGLNTIPVVFPWTKFGSALESKNKLFNQFEQIIVRRKKENNFGSDILGILLTVQEQMNYELTPREIVGQMVNLLSLGKKELSSALSSFFILTSEHLDVLKLLQIEQEKMDVSEPLSLDKYKKMVYLEQVIKEVLRLVPPVSGGLRKIIEDCSFQGFRIPKGWHAYYYISSVLKDPEIYKQPEIFNPERFNPTNAEDKKKPLCYIPFGGGARECIGKEFAYLVIKIFISALLDNCSWKFKENQDLTINTFPVARPAHKIEVCFTPK
>NC_008312.1|WP_011612315.1|4296675_4298742_-|elongation-factor-G
MSEKVASNVRNIAIVGPYLSGKTTLLESLLSITKAISRKGSVKDGNTIGDGSPEARDRSMTVEINAASTKYDGINFTFLDCPGSIEFAQETNNALIGAGAAIVVCEPDPARVLTLAPLLKFLDDWEIPHIVFINKMDRVCRDETHCKSNFGEVLEALKTVSNRPIVPHQYPIAKNNQLIGFIDLVTEQAYHYHPGAPSDPVTIPESLKVEEQAAREQMLEELANFDDNLLEELVENIEPPTEEIVADIKMELSADLIVPVFVGVAEKDSGVRSLLDALVRETPVPKETAKRRGLKSNSETPIAQVLKTYYTPQGGKLSLVRVWQGEIIDGMILNGVRIGGIYRLMGQQTESLELAKTGEIVALSRMEGIHTGDTLTIDADGKTKLPRVILLPPVFAMAIAPENRKDEVKMSSALTKLLEEDPALIWEQHGDTHEVIFWGQGEIHLQVSLERLHRKYNVSMKTYLPRVPYKETIRKKTTSHGRYKHQSGGHGQFGDVYLDIQPLPRGSGFNFSETVVGGVVPKQYISGVETGVREYLQQGPLGFPVVDVAVTLTNGSHHSVDSSEQAFKQAARVAMQQGMSDCQPVLLEPIALVDIFAPNEFTSKVLQLISIRRGQILGYESMTDWERWDKTSAYLALSEMQDLIVELRSQTMGVGSFNWQFDHLQEVPNKLAEKVLIKNGNGNGRGHG
>NC_008312.1|WP_011612314.1|4294716_4296081_-|DUF1800-domain-containing-protein
MADIKILHLINRLSLGPTPGQLEKIKNIGVENYIQSQLEPNSIPYQKLLIQKLKYLDTLPLTPSEIIKELQQLQQQGKELKLDRIALNRIKQRFEQKVFLQGSKGRFLRNLESPRHLEEVMVDFWYNHFNVFGRQGLNRLYFSCYEQQAIRPYALGKFRLLLGATAHHPAMLIYLDNWQSRRGRINENYARELLELHTLGVDGGYSQDDVMALAKILTGWGLPPNNKRAEDKDGFYFDQKRHEPGDKFFLGQTIKENGIAEGETALDILASHPSTARYISYKLAQTFVLDQPSESLVKVLSQSFLESDGDISRVLNTLFNSSEFWQPEVYNSKFKNPYRFVVSAMRAIGNEVDNFRPINGILDQLGMPIYGCITPDGYKNTKDAWLDSDTMIRRSSLAVPLSGGLLGRGKPISAEKLMGTLGNNFSAQTRGVIDQSPGDLRAALIFGSPEFMRY
>NC_008312.1|WP_011612313.1|4291520_4294466_-|ABC-transporter-substrate-binding-protein
MGGISPELYSKLSASLSRCEQFNSNEELQSFFNGHRQLSLWANSLPQGINTDQRVTHVIGFLVGKYHTNKNGLVILVRLLCETFDREDSRHSTLSKLEKELNKQLNSVDNKTSFNWLHLTDFHQVIKEQNGGSSRVKKRFFEDLNRLHEKSEPWDLVLFTGDLTQEGSAEEFEKLDQLLEQLWAKFQEWGSSPKLLAIPGNHDLVRPNQKEPAVRLLKRWSEEPEVQQEFWEDAKSDYRLVMAEAFANYMAWWKRQPWKPEHLKAGILPGDFSATIEKNSAKLGILGLNTSFLQLIGENNEGKLAIHTHQFHQACDDNNTQNWARKHRACLLLTDHPVDAQMHLNTKITAGYPFVLYLRDHTDTKAKQIWHYYTVNKIELELIKGKDQLKSWFLEASREGGKIQEWEIPIFNDRLNSIPSRPPVGKEELIGDEPGLTQNLTRGITLFLSQNPTGWIISFLLILIDIFSIYRWLIYLPRHEPLGDNISIGEEILVESSRPLEKENGVKEVQYCQKSWNHFQAIWKNNTKIQNCFAGVANTLKESWKNERRDPETLIYINNAFLEHIKADPYTIAVVVPVIDQNEQVNGELAEEILRGVAQAQTEVNLSLFKKKQFSFLPFPNVDLKAKRFNDNDNDKGLKVIIANDANSEDGAENVAKKIVGRPEILGVVGHWASEMTMATKDIYDDAKLVMVSPGTTTSKLTAEERVDVFFRTTTTTIEQAENMVNSLLNKNQTRVVIFYNPKSYYSADLKKQFEEKFEGKGEIINLSLNMDYFAEDNFKVKDAINEARRQAGDQEFAIVLISDGQVSDAFDNSLKIIEENGGQNWIVANWSVYSPRTLKIAQDQSQETRYQLLEKLILIVPGHPLNNSDFFDTAVKLWEGYVSARTAFSYDAMQVILKGIQEQGTRPTSKGIQKTLADENFIVQGATGEIIFKSGTGDRQKVPLNSIRVYRCPSQPSGFMFIPDKFSTPEEAKVKCSNSE
>NC_008312.1|WP_155994421.1|4289907_4290909_-|hypothetical-protein
MVSNKLKEANTPGLLVMLNLDILIKTRHQEYGCIFIIFLENLRDEYYEEDEMWHRINNLWNKVKKELENPSLPLNSSTSLGNNNNSQLFQSIIDIDFSEQEDTVRKAIKCQKSHKRTGAFLIDGYDENCGQKALLTRLLRKLPELSNGRKIQRDLTRMSDIRELWGKISSEFFGSNTTDEQVINAILQCLETQNLIFIFSGLHRTFTGFLPDLIKKFWWPIVEKATHQKTYLLMFLVDDKGIVCKSGVSLTWKFENSKYPKDPLCLPETGKFSYYHLETWKNSVVRKNMVPESISVDELLQKSQGGVPELVYRQICDYCGRSWEGGLAKWLIQ
>NC_008312.1|WP_044136805.1|4288975_4289923_-|MoxR-family-ATPase
MVDSVIPRLYTGERQPSEQECELHGLEPYIPSPELVEAVNLTIFLQKRPLLLKGEPGSGKTRLARAVAYELGLPYEPWYIQSTSKAKDGCYTYDAIARLHDAQLARLDGQKLSRVDNLWNYIKLGPLGRAFENSQRTVILIDEIDKADIDFPNDLLQVLDEKRFTIPEIKSQEKEVEKEYEIKAKEPPIIFITSNEEKDLPDAFLRRCLFYYIEFPNEAELVNIVKAHFPEAAPEVMRKAVWRFGELRKQMERDSGKTGKKVSTSELIDWFTILRQYPEEEVLGKLNGELPFAQVLLKYWHDYREYLYSSQEERK
>NC_008312.1|WP_011612310.1|4287743_4288979_-|hypothetical-protein
MNVVEEVPLLKVLLSLFYSLRQYGLPLGVEDYMLVLRALQGGFGIGDRDSLERLCCTLWTKSEQEARLLHQLLGRAITNAPSSAELPQPVEDTPNPSPTSASTRPVSKESEEVMDSSTLPSTATPVRNISEQLEEKAPLKEPEIPVSKPSPLTDIPLEIDEPELVIQAIRHYNRSNEMISEYQDLAAQYLPVTPRQIKQSWRFLSRSVPQGISDKLNVPATVAKICQQCILIEAVLMPNYVNRVKLVLLVDQGGSMIPFHHLSRQLIDKARRGGNIEQASVYYFYNYPEIYFYSDPTRLKAQLITDILGAIDERAGVLMVSDAGAARSNYNPERIECTQRFIEQLRQSVRYYAWLNPMPNDSWQGTTAGEIARFVPMFEMSPQGFNAAINALRGRYVYGKDFYELSRQKSL
>NC_008312.1|WP_081432547.1|4284495_4287171_-|tetratricopeptide-repeat-protein
MVSFTSGDLEGATKQFSQLSRWERQVKIAGVSLSIPDEIPLISVELSFLEELLNIVSDNDDNPQWKIYPFLEANLERLNEDLIGLLQEWSTNILLNTEPVELHRIGSSLTRFSNLLGNFTLGNIAINLEIAITGYQIACQIFRREEFPKEWGIIQNHLGIAYSNRIRGDKAQNIESAIAACQQALMVLTQTDFPFEWAATQNSLGNGYSERIRGDKAENIEVAIAAYEQALLVYTQTDFPMDWAMTQNNLGNAHRDRIRGDKAQNIEAAIAAYQQALLVYTQTDFPMDWAMTQNNLGAAYSDRIRGDKAENIEAAIAAYQQALLVYTQTDFPMDWANTQNNLGIAYRNRIRGDKAENIEAAIAAYQQALLVYTQTDFPINWAMTQNNLGNAYSNRIRGDKAENIEAAIAAYQQALLVRTQTDFPINWAMTQNNLGNAYRDRIRGDKAENIEAAIAAYKRALQVSTQTDFPIDWAGTQNNLGNAYSDRIRGDKAENIEAAIAAFQQALLVYTQTDFPMDWATTQNNLGNAYSDRIRGDKAENIEAAIAAYQQALLVRTQTDFPMDWAGTQYNLGIAYSDRIRGDKAENIEAAIAAYQQALLVRTQTDFPMDWATTQNNLGNAYSDRIRGDKAENIEAAIAAYQQALLVYTQTDFPMEWATIQNNLGNAYSNRIRGDKAENIEAAIAAYQQALLVRTQTDFPMDWATTQNNLGAAYIYRIRGDKAENIEAAIAAYEQALLVYTQTDFPMEWATIQNNLGNAYRNRIRGDKAENIEAAIAAYEQALLVYTQTDFPMEWATIQNNLGNAYRKINQDLAQAAKDIKNLLNQLSEDYPNDSYRVLSAKAMDEVDKNPQLKYRIIRGLKAGGLAALEKMIDHPVAQFLIEGVKEVLNP
>NC_008312.1|WP_011612308.1|4283569_4284199_+|type-I-restriction-endonuclease-subunit-R
MVKTIPASQIDLYSLEENFGLKRAYEPTFFPEWQENLPELTELEKQELVQLKADYLRLSKRPMLEPLVKMVVLSPLLRAAGFYREPFFLSAEKQIKITSEDGGAIVTGKIDILVYTPQFWVLVIEAKRVEYSLQVGIPQILAYMLDSPEIEQSAFGFVTNGSEFRFVKLLKRDTIQYGLSRLFSIDSGEDLYTVVSIFKSLAQFVIQQN
>NC_008312.1|WP_011612318.1|4303654_4305139_+|insulinase-family-protein
MLSHQKKITRSKLFLIAFLVIVILLYILGRMPAIAITPPKHYTELEFPPLPKLELPEYTRFKLENGIVVYLMEDHELPLIGGRALFRTGSRFEPENQVGLANLTGTVMRTGGTTQHSSEYINQLLEQKAAAVETGIGGTAGSARFSCLTEDLAKVFELFTEVIREPVFTEEKLDLAKQQWQGNIARRNDDPGSIASREFQKLIYGRESPYARTVEYETLNNISQEDLIDFYTKYFHPENMILGIVGDFNTKQMRSLVTEKLGDWQPSRQALKFPLPKVTQAEVGNIFFVEQPQLNQSYIQMGHLGGKLDNPDYTALSVMNSILNGLGGRLLNNIRSRQGLAYSVSAYWSANYDYPGVFVAGGQTRSDATVAFIQSINEEIELIRTQPITQEELKRAKDSALNSFIFNFQDPAQTLSRLMRYEYYDYPQDFIFRYRQELEKITVADVQRVAQKYLQPEKMVTLVVGNKEAIQPPLSTLGDGIEITSIDITIPEPS
>NC_008312.1|WP_044136808.1|4306233_4306575_+|CHAT-domain-containing-protein
MIAVYINQMPLLVGDHSAWLRTETSVWSVSDQGTLGLMTEFYTHLNSVKIKSEALIQGQLAMLQGKVVITYRELRGSNTRGVVKLPSAFANIKNQNLSHLYYWEGFTIVVSSW
>NC_008312.1|WP_011612320.1|4307060_4311179_-|glycerophosphoryl-diester-phosphodiesterase
MARLKSFTVLSADTFAEGPPSGKFIETNNRDVPFDSQPVQGFSGVEFAPGSEDGSTYWFLSDNGFGSQGNSADYLLRLYKVNPNFAGAENGDTKVEVQDFIQLADPNNLIPFDIFNEDTSDRFLTGADFDTESFVIDNNGDIWVGDEFGPYILHFDSTGTLLEAPIATPNIEISFNSLSGEAPLVIGHRGASGSRPEHTLEAYRLAIEKGADFIEPDLVITADGVLIARHEPLLDDTTNVAEVFAPERQSTKFLDGVETTGYFAEDFTLEEIKQLRAVQPRDFRDQSFNGQFEIPTFQEVIELVQKMEESGFEVGIYPETKHPTFFDQQGLSLEEPLIQTLQNTSFTDPDRIFIQSFEFANLIDLQKQLNAQSLGDIPLVQLYGNTTEGADPNSTFSSPFDIRFNVAQDNDLAAIYGQEFLNAVEVSLSENTVYADLDSEEFLEVISGLYAEGVGTWKNNILLRESLDTRVDGNGDGVAEISTQLTGEITSFIEDAHDAGLQVHPYTLRDEERYLTLKPDLEAFGTGTPQTAEEEFQQLIDIGVDGFFTDFPGTGRKVLEQNDSNDEVRSPQNPEISFNSLSGEAPLVIGHRGASGSRPEHTLEAYRLAIEKGADFIEPDLVITADGVLIARHEPLLDDTTNVAEVFASERQSTKFLDGVETTGYFAEDFTLEEIKQLRAVQPRDFRDQSFNGQFEIPTFQEVIELVQKMEESGFEVGIYPETKHPTFFDQQGLSLEEPLIQTLQNTSFTDPDRIFIQSFEFANLIDLQKQLNAQSLGDIPLVQLYGNTTEGADPNSTFSSPFDIRFNVAQDNDLAAIYGQAFLNAVEVSLSENTVYADLDSEEFLKVISGIYAEGVGTWKNNILLRESLDTRVDGNGDGVAEISTQLTGEITSFIEDAHDAGLQVHPYTLRDEERYLTLKSDLEAFGTGTPQTAEEEFQQLIDIGVDGFFTDFPGTGRKVLEQNDPNLATSSGYKGMAFSRDRQTFYPLLGGTVEGDPDNALRIYEFDSVSSSFEEELVGFYPTDVTGHTIGDFTPINESEFLVIELDDRQGNEAEFKKIFKIDIYEVDDQGFVEKEEIVDLLDIEDPNDLNGDGDTSFNFPFSSIENMLVIDENTILVANDNNYPFSKSRGDDIDNTEIIQIELEQPLLVDKGLLIKGTPKTERLIGGVGDDTIIGLNGADTLAGRIGNDQIIGSRGNDLLLGQDGNDELQGRQGNDHLLGGDGDDQLNGGQGRDRINGGPGDDTLTGGASIDRFIFNSNEEFESDNFGIDTINNFQLDLRTNEDGNQGDLILLDKSSFTELNSTAGIGFSVNNDFETVNTDNSVDDSDAFIVYSEKSGGLFYNVDGESTQFAILDGAPNITEDNFQIRN
>NC_008312.1|WP_044137537.1|4313546_4314593_+|ion-transporter
MINIRKKLQCQSWQENIYYIFEYSNPKNFLSLLDDLIITILTSISVIAFILDTSPKFSQHYPEQLKLIEILVTIFFTIEYLIRIWICTVNPKYNHPIYGRLRYVITPLALIDIVAILPFYLQVLFPSLEFIKFTLLLRLFRLFKISRYSESLRTIFKVIAAKKEELIATLLVVIFVLVFVSSLMFLVESEVQPNKFSSILETMWWGVVTLTTVGYGDVYPVTHLGKLLSATVAFLGIGIFALPAGIIASGFAEEVQKRRVKKIVHPVGKDIKVTSETVVGPHPDLRHHNHTKQEKEKAIAHYIDESSEIMKLCIETANKKYGNYFKNEEIIKDLAILLYYETTHKFHH
>NC_008312.1|WP_011612322.1|4314811_4315546_-|energy-coupling-factor-ABC-transporter-ATP-binding-protein
MQEDKSQAGVYVKNLLFQYSQNDPILHNLSLTIKPGERVALLGSTGTGKSTFMETLVGLKKALSGEIWIQGILLEQKTLSQVHSQIGFCFQNPDDQLFMPTILEDITFGPLNYGLPLETAKEVAQNLLVKFGLEKYAHRSVYELSGGQKRLAALAAVLALKPEILILDEPTNGLDPLWRRNLAEIILQLPMQIILIASHDLNWVSKVTERALILQYGQIQVDTSTENILRDTSILESYDLPFNY
>NC_008312.1|WP_011612323.1|4315772_4316561_-|cobalt-ECF-transporter-T-component-CbiQ
MKFALDEYANLNSPIHRWDVRYKLIGLISLMFAFATVNSWYLIPLMLFLSIILYGISKLPLSFLANRLRYPGFFLLGVIFLLPFLSGQTIVWQLGFLTIRQEGCLAVILIVSRFFAIMTTCLVLFGTSSFLTTLKGMSNLGISPIITDMLMLSYRYLFELSNQLKMMLNATKLRGFKKSKISWRNLSVYAALTSSIIVRSYQQAERVYKAMLLRGYGNLSNNKSHPQYSTSKNGFQFGSDVIYLFISLIVAVSLIVIEMFLG
>NC_008312.1|WP_011612324.1|4316787_4317432_-|cobalt-transporter-CbiM
MHISEGILPAQLCISGYGFTSLITWYSLRKINRLANPQASIPKASLLTAAFFVASSIHIPMPIGSVHLVLNGLLGTLLGYYAFPAILIGLFLQVIVFGHGGLTTLGINAIIMGIPAILAYQIFQLRHILGNKINENLSIKILGFIAGATAIGVSSLIFFSLIITNIPSGFNTSLEEKAIYGLMISHIPLMGIEGILTAMIVSFMHRVMPELLPS
>NC_008312.1|WP_011612325.1|4317525_4318032_-|carboxypeptidase-regulatory-like-domain-containing-protein
MKWQLVIPLIFLSLLSLEGKASPHGVKIQHQITKAIKINAIYDSGNPLSNASVTVYAPNFPNKPWLQGMTDEEGNFIFAPDHYQPGYWEIKVRQAGHGNLVSVPFQVDKLENSPRKNISKSSYYLASTTRDYNPIQRGLMIGCVIWGFVGTSLFFWRFPTQEQPQENR
>NC_008312.1|WP_011612326.1|4318431_4319469_+|IS630-family-transposase
MNIIDKLNDFINQTKESKEIKRALAVKMTLSGKSYHEVKELLNVSHSFISEWKNQALFHGVESLRLQYQGRQGYLKTVEKEKTIEWLRAQDYLRLSDLKNYLQEQYDVVFESNQSYYNLFKEAGISWKKTQKKNPAKNDELVEVKRKEIEEFLAKWQPEIETGKLTVFMIDECHLLWGDILGYAWGKTDERIEIAIKNEKERQTYYGALDYKTKEFLVQEYESGNTKNTIEFIKYLQKQRPGNKLAIFWDGATYHNSQEFREYLMTINQYLSEEELLINCTRFAPNAPEQNPVEDIWLQTKNFSITFYHLCSSFKVVKWLFKFFADGQIFNFPKLFQYKILPQPT
>NC_008312.1|WP_155994423.1|4319924_4320782_-|DUF4382-domain-containing-protein
MRIRKLLLMLLTLTFVTPTSLLSSCRNQIDQDNTNSTQIIDKTKGNLKLRANGEDFVRKGFITKDGWKITFDKLYINLVEVTAYQTDPPYKAETGAKLEAKEKVILTKSKVVNLAEGNETAETILVSEISAPPGHYNAISWKMLKATKSPVQGYSLLMSGTATKDSKTISFIVKIDHELEFTCGDFVGDQRKGILKAGETAELETTFHFDHLFGDSNANPDEEINTEALGFAPLAAIATAGKVEVDMETFKKKLSPTNYEKFMAILPSLGHVGEGHCDGQILKRE

Crispr_ID: NC_008312_35

• CRISPR_ID: NC_008312_35
• CRISPR_location: 4398820-4398952
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NC_008312_35

Consensus_repeat	Method
AGATAAAAATTCCCCAGTAGCGATCGCCGCTCAAAAA	CRISPRCasFinder

spacers of NC_008312_35

>35.1|4398857|59|NC_008312|CRISPRCasFinder
AACAGTCAAACAATACATCCAACTTTTGCCCATCCAGGAACTTCAAAAGACAACTGATA

CRISPR arrays and Neighbor proteins around NC_008312_35

CRISPR arrays

The CRISPR arrays of NC_008312_35

>merge|NC_008312|35|4398820-4398952|CRISPRCasFinder
AGATAAAAATTCCCCAGTAGCGATCGCCGCTCAAAAAAACAGTCAAACAATACATCCAACTTTTGCCCATCCAGGAACTTCAAAAGACAACTGATAAGATAAAAATTCCCCAGTAGCGATCGCCGCTCAAAAA

>NC_008312|35|29|4398820-4398952|CRISPRCasFinder
AGATAAAAATTCCCCAGTAGCGATCGCCGCTCAAAAA	AACAGTCAAACAATACATCCAACTTTTGCCCATCCAGGAACTTCAAAAGACAACTGATA
AGATAAAAATTCCCCAGTAGCGATCGCCGCTCAAAAA

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_008312.1|WP_011612360.1|4388851_4389517_-|hypothetical-protein	unknown	unknown	unknown
NC_008312.1|WP_044136817.1|4403665_4403878_+|hypothetical-protein	unknown	unknown	unknown
NC_008312.1|WP_011612357.1|4384040_4384712_-|hypothetical-protein	unknown	unknown	gnl|CDD|226790
NC_008312.1|WP_011612361.1|4391623_4391959_-|hypothetical-protein	unknown	unknown	unknown
NC_008312.1|WP_011612369.1|4405802_4406363_-|guanylate-kinase	unknown	unknown	gnl|CDD|234719
NC_008312.1|WP_011612374.1|4412469_4413099_+|ribonuclease-III	unknown	unknown	gnl|CDD|238333
NC_008312.1|WP_011612373.1|4410978_4411827_-|S-formylglutathione-hydrolase	unknown	unknown	gnl|CDD|131868
NC_008312.1|WP_011612362.1|4392553_4393909_+|MATE-family-efflux-transporter	unknown	unknown	gnl|CDD|240554
NC_008312.1|WP_011612368.1|4404603_4405752_+|extracellular-solute-binding-protein	unknown	unknown	gnl|CDD|270379
NC_008312.1|WP_011612364.1|4396696_4398478_+|SUMF1/EgtB/PvdO-family-nonheme-iron-enzyme	unknown	unknown	gnl|CDD|224182
NC_008312.1|WP_011612372.1|4409175_4409979_+|phosphoadenosine-phosphosulfate-reductase	unknown	unknown	gnl|CDD|234997
NC_008312.1|WP_011612358.1|4385467_4386232_-|aldolase	unknown	unknown	gnl|CDD|226356
NC_008312.1|WP_011612366.1|4399305_4401162_+|SUMF1/EgtB/PvdO-family-nonheme-iron-enzyme	unknown	unknown	gnl|CDD|224182
NC_008312.1|WP_155994430.1|4392159_4392315_-|hypothetical-protein	unknown	unknown	unknown
NC_008312.1|WP_011612370.1|4406495_4406747_-|DUF370-domain-containing-protein	unknown	unknown	gnl|CDD|179823
NC_008312.1|WP_044136815.1|4382743_4382977_+|hypothetical-protein	unknown	unknown	unknown
NC_008312.1|WP_011612371.1|4406935_4408687_+|fibronectin/fibrinogen-binding-protein	unknown	unknown	gnl|CDD|336217
NC_008312.1|WP_011612367.1|4402323_4402839_+|cupin-domain-containing-protein	unknown	unknown	gnl|CDD|380376
NC_008312.1|WP_011612359.1|4387207_4388773_-|family-10-glycosylhydrolase	unknown	unknown	gnl|CDD|224563
NC_008312.1|WP_011612363.1|4394348_4396478_+|DNA-binding-protein	unknown	unknown	gnl|CDD|226699

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_008312.1|WP_011612357.1|4384040_4384712_-|hypothetical-protein	gnl|CDD|226790	COG4340, COG4340, Uncharacterized protein conserved in bacteria [Function unknown].	2.02131e-90
NC_008312.1|WP_011612362.1|4392553_4393909_+|MATE-family-efflux-transporter	gnl|CDD|240554	cd13149, MATE_like_2, Uncharacterized subfamily of the multidrug and toxic compound extrusion (MATE) proteins. The integral membrane proteins from the MATE family are involved in exporting metabolites across the cell membrane and are responsible for multidrug resistance (MDR) in many bacteria and animals. A number of family members are involved in the synthesis of peptidoglycan components in bacteria.	0
NC_008312.1|WP_011612369.1|4405802_4406363_-|guanylate-kinase	gnl|CDD|234719	PRK00300, gmk, guanylate kinase; Provisional.	7.44547e-105
NC_008312.1|WP_011612374.1|4412469_4413099_+|ribonuclease-III	gnl|CDD|238333	cd00593, RIBOc, RIBOc. Ribonuclease III C terminal domain. This group consists of eukaryotic, bacterial and archeal ribonuclease III (RNAse III) proteins. RNAse III is a double stranded RNA-specific endonuclease. Prokaryotic RNAse III is important in post-transcriptional control of mRNA stability and translational efficiency. It is involved in the processing of ribosomal RNA precursors. Prokaryotic RNAse III also plays a role in the maturation of tRNA precursors and in the processing of phage and plasmid transcripts. Eukaryotic RNase III's participate (through direct cleavage) in rRNA processing, in processing of small nucleolar RNAs (snoRNAs) and snRNA's (components of the spliceosome). In eukaryotes RNase III or RNaseIII like enzymes such as Dicer are involved in RNAi (RNA interference) and miRNA (micro-RNA) gene silencing.	3.74937e-24
NC_008312.1|WP_011612373.1|4410978_4411827_-|S-formylglutathione-hydrolase	gnl|CDD|131868	TIGR02821, S-formylglutathione_hydrolase, S-formylglutathione hydrolase. This model describes a protein family from bacteria, yeast, and human, with a conserved critical role in formaldehyde detoxification as S-formylglutathione hydrolase (EC 3.1.2.12). Members in eukaryotes such as the human protein are better known as esterase D (EC 3.1.1.1), an enzyme with broad specificity, although S-formylglutathione hydrolase has now been demonstrated as well. [Cellular processes, Detoxification].	2.51619e-156
NC_008312.1|WP_011612368.1|4404603_4405752_+|extracellular-solute-binding-protein	gnl|CDD|270379	cd13661, PBP2_PotD_PotF_like_1, The periplasmic substrate-binding component of an uncharacterized active transport system closely related to spermidine and putrescine transporters; contains the type 2 periplasmic binding fold. This group represents the periplasmic binding domain that serves as a primary polyamine receptor of an uncharacterized ABC-type transport system from plants and plant-symbiotic cyanobacteria. Polyamine transport plays an essential role in the regulation of intracellular polyamine levels which are known to be elevated in rapidly proliferating cells and tumors. Natural polyamines are putrescine, spermindine, and spermine. They are polycations that play multiple roles in cell growth, survival and proliferation, as well as plant stress and disease resistance. They can interact with negatively charged molecules, such as nucleic acids, to modulate their functions. Members of this family belong to the type 2 periplasmic-binding fold superfamily. PBP2 is comprised of two globular subdomains connected by a flexible hinge and bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap.	1.12161e-105
NC_008312.1|WP_011612364.1|4396696_4398478_+|SUMF1/EgtB/PvdO-family-nonheme-iron-enzyme	gnl|CDD|224182	COG1262, COG1262, Uncharacterized conserved protein [Function unknown].	1.88641e-75
NC_008312.1|WP_011612372.1|4409175_4409979_+|phosphoadenosine-phosphosulfate-reductase	gnl|CDD|234997	PRK02090, PRK02090, phosphoadenylyl-sulfate reductase.	1.66081e-116
NC_008312.1|WP_011612358.1|4385467_4386232_-|aldolase	gnl|CDD|226356	COG3836, HpcH, 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase [Carbohydrate transport and metabolism].	1.74799e-67
NC_008312.1|WP_011612366.1|4399305_4401162_+|SUMF1/EgtB/PvdO-family-nonheme-iron-enzyme	gnl|CDD|224182	COG1262, COG1262, Uncharacterized conserved protein [Function unknown].	3.39382e-78
NC_008312.1|WP_011612363.1|4394348_4396478_+|DNA-binding-protein	gnl|CDD|226699	COG4248, COG4248, Uncharacterized protein with protein kinase and helix-hairpin-helix DNA-binding domains [General function prediction only].	9.36254e-107
NC_008312.1|WP_011612370.1|4406495_4406747_-|DUF370-domain-containing-protein	gnl|CDD|179823	PRK04323, PRK04323, hypothetical protein; Provisional.	2.28333e-48
NC_008312.1|WP_011612371.1|4406935_4408687_+|fibronectin/fibrinogen-binding-protein	gnl|CDD|336217	pfam05833, FbpA, Fibronectin-binding protein A N-terminus (FbpA). This family consists of the N-terminal region of the prokaryotic fibronectin-binding protein. Fibronectin binding is considered to be an important virulence factor in streptococcal infections. Fibronectin is a dimeric glycoprotein that is present in a soluble form in plasma and extracellular fluids; it is also present in a fibrillar form on cell surfaces. Both the soluble and cellular forms of fibronectin may be incorporated into the extracellular tissue matrix. While fibronectin has critical roles in eukaryotic cellular processes, such as adhesion, migration and differentiation, it is also a substrate for the attachment of bacteria. The binding of pathogenic Streptococcus pyogenes and Staphylococcus aureus to epithelial cells via fibronectin facilitates their internalisation and systemic spread within the host.	2.74586e-150
NC_008312.1|WP_011612367.1|4402323_4402839_+|cupin-domain-containing-protein	gnl|CDD|380376	cd06121, cupin_YML079wp, Saccharomyces cerevisiae YML079wp and related proteins, cupin domain. This family includes eukaryotic, bacterial, and archaeal proteins homologous to YML079wp, a Saccharomyces cerevisiae cupin-like protein of unknown function that structurally resembles plant seed storage and ligand-binding proteins (canavalin, glycinin, auxin binding protein) as well as the bacterial RmlC epimerase. YML079wp is non-essential in yeast and localizes to the nucleus and cytoplasm. The presence of a hydrophobic ligand within a well-conserved binding pocket inside the cupin beta-barrel and sequence similarity with bacterial epimerases suggests a possible biochemical function for YML079wp and its homologs. Also included in this family are Shewanella oneidensis So0799, Agrobacterium fabrum Atu3615 and Branchiostoma belcheri Bbduf985. Proteins in this family belong to the cupin superfamily with a conserved "jelly roll-like" beta-barrel fold and forms a homodimer.	1.93186e-68
NC_008312.1|WP_011612359.1|4387207_4388773_-|family-10-glycosylhydrolase	gnl|CDD|224563	COG1649, COG1649, Uncharacterized protein conserved in bacteria [Function unknown].	6.38107e-82

Protein sequences

>NC_008312.1|WP_011612364.1|4396696_4398478_+|SUMF1/EgtB/PvdO-family-nonheme-iron-enzyme
MQSEQILRNRYKVIKSLGTGGFGYTYLAEDLDLPGYPKCVVKHLKPKSPDSTVLNIARKLFLREADILYKLGNDSDQIPRLFAYFQEQREFYLVQEYIEGQDISRELTPGKKLSESDTIALLKGILEALTVAHQNNVIHRDIKPQNLMRRRSDNKIVLIDFGAVKEIDVLTINQQGATTLTVAVGTPGYMPSEQSNGKPKLSSDIYAVGMVGIRALTGKEPQSLLTDPKTGNVIWRNEAQVSNRLADILDKMVHEYFPQRYENAMEVLDVLQEARKKPNPPKPTQRPAAESTLNVNPSQPRGQGGSWFAGRFFNQKPAKISIQTFTTVTVNRRGEIISRAQGQAEVITENIGNGVSLEMVKIPGGRFLMGSPKKEAERLDKEGPQHYVDVPEFLMGKYAVTQAQWEAVMGNNPARFKGANRPVEKVSWNDATEFCRKLSRITGKQYSLPSESQWEYACRARTTTPFYFGETITPELVNYDGNYTYADAPKGKYRKETTDVGIFPPNAFGLYDMHGNVYEFCQDVWHENYNGAPTDGSAWETGGDSSRRVCRGGSWVNYPGRCRSADRINYDSVGADYIGIGFRLVSFPPRTFE
>NC_008312.1|WP_011612363.1|4394348_4396478_+|DNA-binding-protein
MRLQRQFSEQIITLDTQNPIGGGGEGRIYPVLKNPSLVAKIYHKPTDEDADKLTVMFSHPPDVPIGSGHAAIAWPIDLLRTTNNKHQIVGFLMPRVSRAQPLHIFYNPRNRREQKPLFNYRYLHRTARNFVAAVNALHNSGYTIGDINESNILVTDTALVTLVDTDSFQVRDPYTKEIYRCPVGKLEFTPPELQGQSFRKIDRKPEHDLFGMAVLIFQLLMEGTHPFAGIYKGRGEPPNLEARIQAGHFPYSQKRVPYRTTPTALHWEILHPTIQELFINCFELGHERPELRPDAKAWLQGLRESEDSLVHCQKNHQHWYGNYLKSCPWCARTKLLKGRDPFPSREAVRNKQHLEPALKKGKLLPLKSPKATPSQKPAPPKPIVITRPMGQYQPLLTPVVTKFKPPSLPIIPLPGGGKGLLGIAQDAIFGGFWGVLLAAAVAGLVLGIVNSSIAILGGVVMGIFWGAFFAIACQYVIPMNSSSASLGLTGGLWGGFLAAAITGAVYGIGNRLGAFGQAVVLGGFLGTIWGSVWSYFKPPLAFPVPGRVLGRRGLFLGVIWGAFLGTVIGAILAGIFVFQEAMNDNSNSWDELVSILISSMISAMGVGAMGGVIGGVILGPILGAPTLPLSNNLSGARGALLGGIWGCFLGTIIGIICGGFLPQIVSIDLVEIMRVNGDWTSIFSTIFGAGLGALCGCFSGATWGSMGKW
>NC_008312.1|WP_011612362.1|4392553_4393909_+|MATE-family-efflux-transporter
MKQKLTEGKISTLLLKLTLPTVWGILALLGFSIIDTYFVAQLGTKELAAISFTFPVITFLNSVSIGLGIGVSSCISRAIGKRVQTPVLDRDDYKVKRLTTDSLILSLLVGAILVILGLATIEPLFTALGAKAETLPLIRQYMKTSYLGGIFAVVPIVGNSIIRATGNTFVPSVVMTVAGIVNLVLDPILIFGVGPISGMGLQGAALATVISMVATLAASLFFLHYHQQMICWKLPSFKLLLRNWQNILSIAIPNIGQNIIIPISVSFITSLIATYGTAAVAAFGIASKIEVFCFIVFLALSSSFIPFVGQNWGAKQYNRVYLGGNLGFKFSLFWGAIIAIALAIGGSWLVSIFDSDPEVIEVATKYLLIMPISYGTLGITLISSATFNALGKPLPSVMMSLIRVLFLYVPLTYLGSWLLGINGIFYGTCFANLVVGIGAYFYFNKTFKFNN
>NC_008312.1|WP_155994430.1|4392159_4392315_-|hypothetical-protein
MKESTGDYFQYFPEKFIEQYAFEYGVKKDDIAIMSALLLSKSYQEIVDEKG
>NC_008312.1|WP_011612361.1|4391623_4391959_-|hypothetical-protein
MKTENEVVWSGRSNISSFVMIEEELEILTRWILEDKFRLVTIFGLKGIGKNFLSVKLTEKIKDKFEFVIWRSLSLDPKIRLLLTWLIFTQVLNKFQIISTRKLLFSNFNKC
>NC_008312.1|WP_011612360.1|4388851_4389517_-|hypothetical-protein
MKKTKLVITLATVVFLAACDVGNNSHINLRNYGYPNRMNQRKMRLKNYYQTNIDANYVVSSCQELMEDEMGFPKNGQWSSVEDITKTQSGWQWQGWVEFDGERNNFLCNVDNNEVVAYPYKKEIYPDSFPDNLSESKNLNASSVVTSCQEFMAYEMGFPKHGNWSSQKDVRKTRKGWEWQGWVDLYGERNKFVCTVDNNGVGVSTNFEDSYNYEYEYNYTY
>NC_008312.1|WP_011612359.1|4387207_4388773_-|family-10-glycosylhydrolase
MRLNYQNYLNYLIMNLISKLLAKIPKNIHFRRKNLLWSCFLILGLTLTQMSSYLPTSRAQQPSSFSPREFRGVWVASVANIDWPSQPGLPVTQQKTELLNILNRMQELNLNALVLQVRPNGDAFYNSTIEPWSGWLTGKQGTPPQPYYDPLEFAIAESHKRNIELHAWFNPYRAQLSPNDGSFASNHAAVKYPQYAYRYGKYVWLDPGAKVVQDQTFNTIIDVVRRYDIDAVHFDDYFYPYPQGGQEFPDYQTYNSYKASGGTLSLSNWRRQNVNNMVERLYQGIHAEKPYVKFGISPFGIYRPGNPPGIVGLDQYESLYADVKLWLAKGWVDYLAPQLYWRIDPPKQSYPVLLNWWLQQNPQRRHIYAGNFLSQLQVSGWPVSEFERQVAISRQRASQLSLGNIFYSMKMFRDNVAGVNNVFKNYVYPTPALPPAMPWLDNQPPAPPMGVQVNSDVISWNVDNIEDVRSWALYQQNGNQWELLQVLNSATNAVRVNPGTYALRAVDRLANESLEEVVTVQ
>NC_008312.1|WP_011612358.1|4385467_4386232_-|aldolase
MPKNQLKQKLKNGEVVLGPFMNCAYPAFVEICGLAGFDFVVIDLEHGPLNILVAEDLCRAADCVGIAPVVRVSKNDPAQIQRALDIGSTGVQVPQIETISDAEIVVQSAKYNPIGCRGLSFGTRAGLYTSAGSNITNKLNAESLVVVHVEGTKGIENMEEIVKVPEIDVIFLGPYDLSQSLGIPGQVNDIRVVELMQKAVEIIRSSGKVVGTFTNNSEAAKKWIDCGVQYIGLGIDVSIFLQGCQALVKGVRGK
>NC_008312.1|WP_011612357.1|4384040_4384712_-|hypothetical-protein
MQKILESINLDYAFMFTHKKVNSISMEGFDPFFADLPVDPYMKAKYRYRRLSRFILSGEKVIKQPHGYIFQGKNYNPLPNYGDVKREYAEIDDKLVALDNFKKMILAFCDSCKIHPEAEIGIHQIRTICYPNSLGNPAPEGIHQDGTDFIGIFVVNRHNIQGGATHLYTAKKEKPVFSKILNPGDLLLANDHEFFHFTTPIKPVIEEMGYRDVFVLTSPSLIH
>NC_008312.1|WP_044136815.1|4382743_4382977_+|hypothetical-protein
MVLTPNELWFSPFIKRDDITIPTQSIQDVHLVNSHLGKRILGHQLIYVQFQISERKDSATWLVADPEQWKMTILSQN
>NC_008312.1|WP_011612366.1|4399305_4401162_+|SUMF1/EgtB/PvdO-family-nonheme-iron-enzyme
MQSGKVLRNHYKIIKSINNGGFGDTYLAQDIDLPGYPKCVVKHLKPKNLDPRVLNVARKLFEREADTLYKLGNDSDQIPKLLAHFQEQREFYLVQEHIEGQDISREMTPGKKLSESDTIALLKGILEALTVAHQNNVIHRDIKPQNLMRRRSDNKIVLIDFGAVKEIDVLSTDQNGQTILTVAVGTPGYMPSEQSNGKPKLSSDIYAVGMVGIRALTGKKPQSLLTDPKTGNVIWRNEAQVSNHLANILDKMVHEYFPQRYENAMEVLDVLLGAKGKINPPKPKQRPTAKTTVNVNPSQPLPNNTITQLRDPAESKLMGRFCNQKPPKTLTQKFTTVTVNRQKPPKNSIQTFTTVTVNRRGEIISRTQGQAEVITENLGNGVSLEMVKIPGGSFLMGSPKTEAGRYDDEGPQHYVNVPEFFMGKYVVTQIQWRAVMGNNPSCFQGASLPVERVSWDEAKKFCQKLSQITGKKYSLPSESQWEYACKAETTTPFYFGETITSELVNYYGNFTYADAPKGTYRKKTTNVGIFPPNAFGLYDMHGNVWEWCADEWHNNYYGAPTDGSVWLNGNENLSPQRGGSLVNYPDLCRSSFRLYFNSRGERSSTTGFRVICDIGRTL
>NC_008312.1|WP_011612367.1|4402323_4402839_+|cupin-domain-containing-protein
MPEKNQLIQNLLENLQLLPHPGGGFYKEVYRSQGIIPKTALSQKFSGDRSYCTSIYSLLTSEDFFGFHKVKQDEIYHFYGGSSLTVHTISQEGNYLKRKLGMDLENGEQPQLVIPAECWFASNVEAEYSYALIGCTVAPGFHFDDFESAQRKTLSEKYPQLKDIIHKFTKE
>NC_008312.1|WP_044136817.1|4403665_4403878_+|hypothetical-protein
MELDVIYNQQESGFLQLTITEYFQRSTKGQWNSLGRHSVLRILKSNSPSTSTPLNRGKKKRDYQFKTFTL
>NC_008312.1|WP_011612368.1|4404603_4405752_+|extracellular-solute-binding-protein
MKRRNFLIGATAITLAEFLAGCETQADLKVKLLKNSIPAQMASKFLGELQSPIKSSFQPIESLNELFYLLQNWQKKLLLEKQQSSINKTENINIANLVTLGDYWLANAIKQELIQPFNSQSLANWNKLPEKWLELVKRNNQGYVDPQGKIWAAPYQWGTTLIAYRVDKFKALGWEPKDWSDLWRPELKGNISLLNQAREVIGLTLKKLGKSYNTKNIDQVEKLKAELVKLNQQVKFYSSNNYLQPLIIGDTWLAVGWSNDILPLLKKRKKIAAVVPQSGTALWANLWVKPAASPENSLTEKWINFCWQPQVAQQMSIITQTSSPIMPKINPNELISDIKNNPLLLLPQEIIEKSEFLAPLANSTIEQYQKLWQEIRQPVHIQ
>NC_008312.1|WP_011612369.1|4405802_4406363_-|guanylate-kinase
MQTGKLIVLTGPSGVGKGTLLSCLLHRHPGLAFSVSVTTRSPRPGEVEGKSYFFVDHDQFREMIESEELLEWAEYAGNFYGTPRVPVIENIEQGRSMILEIELQGARQIQRTFPDALRIFILPPSMAELEERLWGRGQDSEEAITKRLQRATEELEAATEFDIQLVNDSIEDTLQNLDKILFHFRE
>NC_008312.1|WP_011612370.1|4406495_4406747_-|DUF370-domain-containing-protein
MDTQFINIGFGNIVSANRVVTIVSPESAPIKRIINDGRERGQLIDATYGRRTRAVIITDSNHVILSSIQPETVANRFLFNKDD
>NC_008312.1|WP_011612371.1|4406935_4408687_+|fibronectin/fibrinogen-binding-protein
MQPVDYTTLIASCSQLRSQWLPARLEHVIQRDRFTISLALRTLKKRGWLDISWHPQAARICIGDPPPRIPDTFTFSQQLKHQLNGLALIAIAEVSPWERVLDFQFAKRPGEKPLWHLYVEVMTKYSNVILTTVDNLVITCARQINIQQSSVRQIQTGQPYELPPSLTNSIPRVSETQQHWQERISLVPGSLSRNVIKNYRGLSKALVEPMIKTAGLDPQQLTNSLNNSDWEKLFQLWQKWLQALDKLIFNPGWTSTGYTVTGWKAIECVDSVGELLNHYYTQQLNQQEFTQLHHQISQKVNSITAKLQLKAQTFTQRLEQSDGAELLRSQADLLMANLQEWQPGMKNISLPDFETGEIIFIKLDPEKNAVQNAQSIYKKYQKLKRAHTIVKPLLAEVQNEIHYLEQVEAFLSQLNNYRSPEDLQTLEEIREELIQQGILNAPEHHQQNNRKDTEFYRYQTPSGLELLVGRNNRQNDLLTFRVAGDYDLWFHTQEIPGSHLLLRLDAGTIPDEVDLQFVADMSAFYSRGRQSEVVPVIYTKPKFVYKPKGAKPGMVIYNQEQVLWGKPQSAAVHINQKSTTPFN
>NC_008312.1|WP_011612372.1|4409175_4409979_+|phosphoadenosine-phosphosulfate-reductase
MLQQSLIRLNKNGQYNYQDYRYLPELDLGVVNQELSQADPHTLVQWGLKIFKEGLVMSTSFGIQAAVMLHLVTSVIPNIPVIWIDTGYLPAETYKFAEELIERLKLNVKVYQSHISPGRMEALYGRLWAEKDLEALNRYDQIRKVEPMQRALRELKATAWLAGLRGEQTKHRQSLDRISKQSNIYKILPILNWNARDIYQYLTAHNLPYHPFFDLGYTTVGDWHSSRPLTTDDQDERDTRFYGLKQECGLHLPQTQEEAQSLDSSLL
>NC_008312.1|WP_011612373.1|4410978_4411827_-|S-formylglutathione-hydrolase
MSTKIKLVKKHQCFGGTVSYYFHSSSTCNTEMRFSIYQPSLAKSQPLPILYFLSGLTCTEENFMAKAGAQQFANKYGLILVVPDTSPRNTGTFGEDDDWDLGTGAGFYINATVEPWKKHYQMYSYVVEELPEIIAKNFPVQPDKQSIFGHSMGGHGALICALKNPEKYQSVSAFAPIAAPMRCYWGKKAFRNYLGTNTKNWRDYDASELVLTYKYNRPILIDVGTVDPFLAQKQLLPEVFESACQKVGLPLTLRMLKNYDHSYYFITSFIEDHIRYHSEFLN
>NC_008312.1|WP_011612374.1|4412469_4413099_+|ribonuclease-III
MGLNVEAFKKSSIPISKFKHPELLEIALTHPNHIYDRTNIIRPQQKQQVLEHQGLANLGYVVFSRVISKYLSKNFSSLGKATLIIIESDLVSIKMLSEFAKDLKLRQFSQLGKSYKWKHKSEKNKMLAQMFEALIGVIYLEFDKDLERTSHWLVEHFIAEAVNQLLTLAFKDDSDLETDFQLIDWIEVLQSPLLNPNSSYRKNNSFLEC

Crispr_ID: NC_008312_36

• CRISPR_ID: NC_008312_36
• CRISPR_location: 4479665-4479755
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NC_008312_36

Consensus_repeat	Method
AAAAGTTAAAATTATTAATTCCGA	CRISPRCasFinder

spacers of NC_008312_36

>36.1|4479689|43|NC_008312|CRISPRCasFinder
CTCCTATGAAGTCAAATATTTTATAAGTAAAAGGTCAAAGTTT

CRISPR arrays and Neighbor proteins around NC_008312_36

CRISPR arrays

The CRISPR arrays of NC_008312_36

>merge|NC_008312|36|4479665-4479755|CRISPRCasFinder
AAAAGTTAAAATTATTAATTCCGACTCCTATGAAGTCAAATATTTTATAAGTAAAAGGTCAAAGTTTAAAAGTTAAAATTATTAACTCCGA

>NC_008312|36|30|4479665-4479755|CRISPRCasFinder
AAAAGTTAAAATTATTAATTCCGA	CTCCTATGAAGTCAAATATTTTATAAGTAAAAGGTCAAAGTTT
AAAAGTTAAAATTATTAACTCCGA

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_008312.1|WP_011612408.1|4479398_4479650_-|hypothetical-protein	unknown	unknown	unknown
NC_008312.1|WP_011612407.1|4478486_4479398_-|ROK-family-protein	unknown	unknown	gnl|CDD|224851
NC_008312.1|WP_011612404.1|4474214_4475930_+|CTP-synthase	unknown	unknown	gnl|CDD|235437
NC_008312.1|WP_011612405.1|4477043_4477370_-|hypothetical-protein	unknown	unknown	unknown
NC_008312.1|WP_011612416.1|4495868_4496225_+|hypothetical-protein	unknown	unknown	unknown
NC_008312.1|WP_011612402.1|4472263_4472923_+|aminoacyl-tRNA-hydrolase	unknown	unknown	gnl|CDD|235457
NC_008312.1|WP_044137557.1|4493144_4493351_+|hypothetical-protein	unknown	unknown	unknown
NC_008312.1|WP_011612415.1|4494783_4495314_+|phosphoribosyltransferase	unknown	unknown	gnl|CDD|225145
NC_008312.1|WP_011612418.1|4498809_4500057_+|hypothetical-protein	unknown	unknown	gnl|CDD|227245
NC_008312.1|WP_011612414.1|4490873_4491221_-|NAD(P)H-quinone-oxidoreductase-subunit-M	unknown	unknown	gnl|CDD|313802
NC_008312.1|WP_011612406.1|4477416_4477854_-|hypothetical-protein	unknown	unknown	unknown
NC_008312.1|WP_011612413.1|4489708_4490083_+|DUF1823-family-protein	unknown	unknown	gnl|CDD|370156
NC_008312.1|WP_011612412.1|4488287_4489316_+|type-I-glyceraldehyde-3-phosphate-dehydrogenase	unknown	unknown	gnl|CDD|223135
NC_008312.1|WP_011612401.1|4471892_4472156_+|TatA/E-family-twin-arginine-targeting-protein-translocase	unknown	unknown	gnl|CDD|184859
NC_008312.1|WP_011612411.1|4486041_4486311_-|ferrous-iron-transport-protein-A	unknown	unknown	gnl|CDD|377199
NC_008312.1|WP_011612403.1|4473755_4474022_+|DUF3146-family-protein	unknown	unknown	gnl|CDD|371480
NC_008312.1|WP_011612410.1|4484080_4485901_-|ferrous-iron-transport-protein-B	unknown	unknown	gnl|CDD|223447
NC_008312.1|WP_011612400.1|4471575_4471779_+|photosystem-II-reaction-center-protein-PsbH	unknown	unknown	gnl|CDD|179451
NC_008312.1|WP_011612399.1|4471356_4471488_-|photosystem-II-reaction-center-protein-PsbN	unknown	unknown	gnl|CDD|367094
NC_008312.1|WP_011612409.1|4479978_4483209_+|carbamoyl-phosphate-synthase-large-subunit	unknown	unknown	gnl|CDD|235393

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_008312.1|WP_011612407.1|4478486_4479398_-|ROK-family-protein	gnl|CDD|224851	COG1940, NagC, Transcriptional regulator/sugar kinase [Transcription / Carbohydrate transport and metabolism].	3.18039e-75
NC_008312.1|WP_011612401.1|4471892_4472156_+|TatA/E-family-twin-arginine-targeting-protein-translocase	gnl|CDD|184859	PRK14857, tatA, TatA/E family twin arginine-targeting protein translocase.	1.33548e-31
NC_008312.1|WP_011612413.1|4489708_4490083_+|DUF1823-family-protein	gnl|CDD|370156	pfam08853, DUF1823, Domain of unknown function (DUF1823). This presumed domain is functionally uncharacterized.	8.79658e-78
NC_008312.1|WP_011612402.1|4472263_4472923_+|aminoacyl-tRNA-hydrolase	gnl|CDD|235457	PRK05426, PRK05426, peptidyl-tRNA hydrolase; Provisional.	8.60854e-101
NC_008312.1|WP_011612410.1|4484080_4485901_-|ferrous-iron-transport-protein-B	gnl|CDD|223447	COG0370, FeoB, Fe2+ transport system protein B [Inorganic ion transport and metabolism].	0
NC_008312.1|WP_011612415.1|4494783_4495314_+|phosphoribosyltransferase	gnl|CDD|225145	COG2236, COG2236, Predicted phosphoribosyltransferases [General function prediction only].	1.94974e-29
NC_008312.1|WP_011612414.1|4490873_4491221_-|NAD(P)H-quinone-oxidoreductase-subunit-M	gnl|CDD|313802	pfam10664, NdhM, Cyanobacterial and plastid NDH-1 subunit M. The proton-pumping NADH:ubiquinone oxidoreductase catalyzes the electron transfer from NADH to ubiquinone linked with proton translocation across the membrane. It is the largest, most complex and least understood of the respiratory chain enzymes and is referred to as Complex I. The subunit composition of the enzyme varies between groups of organisms. Complex I originating from mammalian mitochondria contains 45 different proteins, whereas in bacteria, the corresponding complex NDH-1 consists of 14 different polypeptides. homologs of these 14 proteins are found among subunits of the mitochondrial complex I, and therefore bacterial NDH-1 might be considered a model proton-pumping NADH dehydrogenase with a minimal set of subunits. Escherichia coli NDH-1 readily disintegrates into 3 sub-complexes: a water-soluble NADH dehydrogenase fragment (NuoE, -F, and -G),the connecting fragment (NuoB, -C, -D, and -I), and the membrane fragment (NuoA, -H, -J, -K, -L, -M, -N). In cyanobacteria and their descendants, the chloroplasts of green plants, the subunit composition of NDH-1 remains obscure. The genes for eleven subunits NdhA-NdhK, homologous to the NuoA-NuoD and NuoH-NuoN of the E. coli complex, have been found in the genome of Synechocystis sp. PCC 6803 which has a family of 6 ndhD genes and a family of 3 ndhF genes. Two reported multisubunit complexes, NDH-1L and NDH-1M, represent distinct NDH-1 complexes in the thylakoid membrane of Synechocystis 6803 -cyanobacterium. NDH-1L was shown to be essential for photoheterotrophic cell growth, whereas expression of NDH-1M was a prerequisite for CO2 uptake and played an important role in growth of cells at low CO2. Here we report the subunit composition of these two complexes. Fifteen proteins were discovered in NDH-1L including NdhL, a new component of the membrane fragment, and Ssl1690 (designated as NdhO), a novel peripheral subunit. The cyanobacterial NDH-1 complex contains additional subunits, NdhM and NdhN, compared with the minimal set of the bacterial enzyme and these seem to be specific for thylakoid-located NDH-1 of photosynthetic organisms. The three subunits of NDH-1, NdhM, NdhN and NdhO are essential for effecting cyclic electron flow around photosystem I, by supplying extra-ATP for photosynthesis in both plastids and cyanobacteria.	2.15006e-72
NC_008312.1|WP_011612403.1|4473755_4474022_+|DUF3146-family-protein	gnl|CDD|371480	pfam11344, DUF3146, Protein of unknown function (DUF3146). This family of proteins with unknown function appear to be restricted to Cyanobacteria.	1.09256e-53
NC_008312.1|WP_011612412.1|4488287_4489316_+|type-I-glyceraldehyde-3-phosphate-dehydrogenase	gnl|CDD|223135	COG0057, GapA, Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase [Carbohydrate transport and metabolism].	0
NC_008312.1|WP_011612404.1|4474214_4475930_+|CTP-synthase	gnl|CDD|235437	PRK05380, pyrG, CTP synthetase; Validated.	0
NC_008312.1|WP_011612418.1|4498809_4500057_+|hypothetical-protein	gnl|CDD|227245	COG4908, COG4908, Uncharacterized protein containing a NRPS condensation (elongation) domain [General function prediction only].	0.000261072
NC_008312.1|WP_011612411.1|4486041_4486311_-|ferrous-iron-transport-protein-A	gnl|CDD|377199	pfam04023, FeoA, FeoA domain. This family includes FeoA a small protein, probably involved in Fe2+ transport. This presumed short domain is also found at the C-terminus of a variety of metal dependent transcriptional regulators. This suggests that this domain may be metal-binding. In most cases this is likely to be either iron or manganese.	2.1169e-14
NC_008312.1|WP_011612400.1|4471575_4471779_+|photosystem-II-reaction-center-protein-PsbH	gnl|CDD|179451	PRK02624, psbH, photosystem II reaction center protein PsbH.	2.59613e-35
NC_008312.1|WP_011612399.1|4471356_4471488_-|photosystem-II-reaction-center-protein-PsbN	gnl|CDD|367094	pfam02468, PsbN, Photosystem II reaction centre N protein (psbN). This is a family of small proteins encoded on the chloroplast genome. psbN is involved in photosystem II during photosynthesis, but its exact role is unknown.	8.00274e-23
NC_008312.1|WP_011612409.1|4479978_4483209_+|carbamoyl-phosphate-synthase-large-subunit	gnl|CDD|235393	PRK05294, carB, carbamoyl-phosphate synthase large subunit.	0

Protein sequences

>NC_008312.1|WP_011612408.1|4479398_4479650_-|hypothetical-protein
MPRNPDEFAIHLLLEGGAREEVRFLSLKDFQTWYSGVVVPKHDSQEFVNVPIKTIQGEYMVVRPSAIIAIRVEPIFNSSIERY
>NC_008312.1|WP_011612407.1|4478486_4479398_-|ROK-family-protein
MNSLVIGIDIGGTSIKLGCFGRDGVCHQSLTVPTPRPATPKAVIDLIKEVISMMIKEPQIYNLGPIQGIGIGVPGPVDAEGKTSIIAINLTDWQDVPLAKLLEEKTGLPVVIANDANCAGLGEAWLGAGSQYKNLIMLTLGTGVGGAIILNSQLFVGHQGAAGELGLITLNLDGPKCNSGNNGSLEQYISVQAVRRETGKEPLELANLALAGDKFALEFWQNYGRLLGAGLASLIYILTPEAVIIGGGISAAAKLFLPATKAEVKRRVLLTSSLKLQLLIAKLGNQAGVIGAAKLAWTKFSDQ
>NC_008312.1|WP_011612406.1|4477416_4477854_-|hypothetical-protein
MELINKAAENVRYRVQPLIYQLPILLKQAAETAIEETPIEKGEVKRKKVLQEKISRSVTNAVQKASRKFSENIQTEIQQGIDREVDRLKDFTTSVDEAFNKIEMEFVDIEFNAEKKTTSHAQAITAALAAFTGYCFSSSFSYWNC
>NC_008312.1|WP_011612405.1|4477043_4477370_-|hypothetical-protein
MERNFKGNFQEAITKEIDKQLREKHLEQEISNLISEPFADLQKSLNQELEALLDNTQNKLAQLRGDRERGVVLNEAKQRELETMRTETQSILSNAERLSKQIVEIIEI
>NC_008312.1|WP_011612404.1|4474214_4475930_+|CTP-synthase
MTKFVFITGGVVSSIGKGIVAASLGRLLKSRGYSVSILKLDPYINVDPGTMSPFQHGEVFVTEDGAETDLDLGHYERFTDTSMSRLNSVTQGSIYQAVINKERRGDYQGGTVQVIPHITNEIKERIHRVAKNANPDVVITEIGGTVGDIESQPFLEAIRQFRKDVRRNNALYIHVTLVPWIASAGEMKTKPTQHSVKELRSIGIQPDILVCRCDRKLSEGLKEKMSEFCDVPVESVITSQDAQSIYEVPLMLETEGLAVQALELLKMEQRQPNLSHWKTLVNRLYHRDKQDIRTSQGKLSITATVEIAIVGKYIQLSDAYLSVVEALRHAAIAVGVDLNLHLVNAEDVETKGARTYLEKANGIIVPGGFGVRGIDGKIATVEYARINKIPFLGLCLGMQCAVIEWARNIAKLDAAHSFEFDPQTPNPVINLLPEQQDVVDLGGTMRLGLYPCRLQGDTLAFKTYQQEVIYERHRHRYEFNNAYRNLFKETGYIISGTSPDGRLVEIIELPAHPFFIATQFHPEFQSRPSTPHPLFHNFFQAANSQEKCDNLSVNNTEETPDNLVSKSSIPN
>NC_008312.1|WP_011612403.1|4473755_4474022_+|DUF3146-family-protein
MISKGLPETTAYIRVTRQSWQKGTIEGEVSAGSFGWQFKWRFRQGKTLSIQPSQGRALIQEPLGRFLEKWDYQLEPGGDYSFTIKAKF
>NC_008312.1|WP_011612402.1|4472263_4472923_+|aminoacyl-tRNA-hydrolase
MKEVAPAANLVIPKLIVGLGNPEPKYDQTRHNIGFTGIDTIANIWQVSLSENRKFKGEFGEGRRPKAEKIYLLKPLTYMNRSGEAISAVVNWYKLPPSCVLIIYDDMDLPMGRLRLRLSGSAGGHNGMKSAIAHLGTQEFPRLRIGIGKPKNITAERGEAKTISHVLGKFSPKENKLMTQVLELVVDAVELSLKQGIEKAMSLYNNRTITENPVSKPPS
>NC_008312.1|WP_011612401.1|4471892_4472156_+|TatA/E-family-twin-arginine-targeting-protein-translocase
MNIFGIGLPEMIVILVVALLIFGPKKLPEIGRSLGQAINSFKAGARDFENEFKREAKHLEEGVKVSTSASEPEKVVDVSSATNTNKN
>NC_008312.1|WP_011612400.1|4471575_4471779_+|photosystem-II-reaction-center-protein-PsbH
MSQRTGLGDILKPLNSEYGKVSPGWGTTWVMAVFIGLFFVFLLIILQIYNSSLLLENVDVDWANLTK
>NC_008312.1|WP_011612399.1|4471356_4471488_-|photosystem-II-reaction-center-protein-PsbN
MEPATVLSISIGVMVVAITGFSIYTAFGPPSKELVDPFDEHED
>NC_008312.1|WP_011612409.1|4479978_4483209_+|carbamoyl-phosphate-synthase-large-subunit
MPRRQDIRKILLVGSGPIVIGQACEFDYSGTQACKALREEGFEVVLVNSNPATIMTDPEIAECTYIEPLTPELIEKVIAKERPDALLPTMGGQTALNIAVSLAKNGTLAKYGVDLIGAKLPAIEMAEDRQLFKEAMGRIGIQVCPSGIASNWEEAKAIAQKIGTYPLIIRPAFTLGGTGGGIAYNQEEYEVMAQGGIDASPVSQILVEKSLIGWKEYELEVMRDLADNVVIICSIENIDPMGIHTGDSVTVAPAQTLTDKEYQRLRDASIKIIREIGVETGGSNIQFAVHPLNGDVIVIEMNPRVSRSSALASKATGFPIAKMAAKLAVGYTLDEIPNDITKKTPASFEPTIDYVVTKIPRFAFEKFPGSQPVLTTQMKSVGEAMAIGRTFQESFQKALRSLETGRAGFGADRWEKIPSLEQVRSGLRTPNPERLFTVRHALLLGMSLEEIYELTGIDIWFLDKMRELINTEKLIKYTPLNELTKEQLWDIKRQGFSDRQIAYCSKTTEDEVRSYRLSLGIKPVYKTVDTCAAEFEALTPYYYSTYEEESEILPSEKRKVMILGGGPNRIGQGIEFDYCCCHASYALGADGFETIMVNSNPETVSTDYDTSDRLYFEPLTKEDVLNIIEAENPVGIIVQFGGQTPLKLAVPLQKYLEQVDAQTKIWGTSPDSIDTAEDRERFEKILRDLDIRQAANGLARSFEDALTVAHTIGYPVVVRPSYVLGGRAMEIVYSDQELERYMKFAVQVEPEHPILIDKFLNNAVEVDVDAIADSTGRVVIGGIMEHIEEAGIHSGDSACSIPYQTLTSAAVETIRQWTVALAKALNVIGLMNIQFAVQGETVYILEANPRASRTVPFVSKAIGIPLAKIASRVMSGKNLEELGFIDEQIPDHVSVKEAVLPFAKFPGIDTVLGPEMRSTGEAMGIDVDFGKAFAKAQLSAGQKLPLEGTVFVSMSDRYKEAVVPVVKDLVDLGLKVVATEGTRKILRLHDLEVGLMLKLHEGRPNVLDGIKNGEIQLIIIIPSGDEARADGIKIRRSALDYKITLITTIAGAKATAAAIRALKSGALEVKAIQDYY
>NC_008312.1|WP_011612410.1|4484080_4485901_-|ferrous-iron-transport-protein-B
MTCHNNKVTISQPTNATKKVALIGMPNTGKSTFFNRITGVSAHVGNWPGITVDLFQAEVKINKEITQFIDLPGIYNFNGFSEDEKVVQNFLENNPVDLVIVVINSSQIDRQIMLPLQVKSLGLPAVLMLNMSDEAKQYGIKIDKEELSKRLSMPVFLISAKYGKGYMNAYMAISEQLKESKNSVQLDTNKIKENISVREIDSILNGTVIMPSQMAQNFTAQVDKILLHPVWGLPLFFLGMFLVFLAIWNIGLPSVDLLEIGVEWVQSSIVEPLVQPFPQVLQDFLINGLWAGVTTVASFVPLIIVFFIIMAVLEDSGYLSRSAYLMDAFMARLGLDGRSFVLHIMGFGCNVPALMGTRVMRSRALRLLTMLIIPFGLCSARLQVFVFIIAAVFPNSKGAIVLFSLYILSFLVAIITAALFQGVYKNEEPFVLEMPPYRFPTWKQVLLRSWGEVREFLVRASGFITVGCIGVWILTSLPSGATGLDTIGGQIGQLMSPIMDPIGINSYLTLSLFFGFIAKEIVIGSLAVIYSMSEQNVSSNIAETVTFIQGYSFCIFCLLYTPCLSTLATLIKEAKSWKFSLLSLVFPLVLAWLSSFIFYQGALALS
>NC_008312.1|WP_011612411.1|4486041_4486311_-|ferrous-iron-transport-protein-A
MNVADLKIGQIAIVDKVLNLDGGQGTVQRLAAMGVVSDKSVQVLRKARFNGPLHIRVGATTEIAIRPHEAEMIVIRTDRDDEINFSEGS
>NC_008312.1|WP_011612412.1|4488287_4489316_+|type-I-glyceraldehyde-3-phosphate-dehydrogenase
MPLKVAINGFGRIGRLVFRAGLNYPDLIEFVGINDLVPPQNLAYLLKYDSTHGRFQGEVTASDDGIKINGKLIPCVSVKNPAELPWKEKDAHYVVESTGLFTTFDSASNHLAAGAKRVIISAPTKDPDKVKTLLMGVNHDLFDPAVDTIVSNASCTTNCLAPIAKVIDDNFGLTEGLMTTVHAMTATQPTVDGPSKKDFRGGRSAAQNIIPAATGAAKAVTLVLPHLKGKLTGMAFRVPTPDVSVVDLTFKTEKSTNYKDICAAMKTAAENSMKGILSYTEDPVVSTDFTGNSHSSIFDAGAGIELNSNFFKVVSWYDNEWGYSNRVLDLMLSMAEKEGKPK
>NC_008312.1|WP_011612413.1|4489708_4490083_+|DUF1823-family-protein
MSKLPTLNIETIQAIIDEKIEDETVNQLVWYYLGYRYDNATCKWDISRVAPEWREEYPEPPNFIEFRPPTVKLTRSIPKENKQLLKRKLGFKGYKIGEFTPVQARRATMANWLLSYMAINDKRD
>NC_008312.1|WP_011612414.1|4490873_4491221_-|NAD(P)H-quinone-oxidoreductase-subunit-M
MLLKSTTRHIRIFAGTVENNELVPDDQALTLDIDPDNELNWNDTAVEQVYRKFDELVESYSGSDLTEYNLRCMGSDLEHFVRSLLQSGEISYNLGSRVNNYSLGLPRVDVDAEAK
>NC_008312.1|WP_044137557.1|4493144_4493351_+|hypothetical-protein
MMNYLNQSFLPAIGITELMFQVYRSGILTKDQRKQLKDLFLYHNLTEEDTTAINRLIHAIRRGWLKMV
>NC_008312.1|WP_011612415.1|4494783_4495314_+|phosphoribosyltransferase
MSDIYISWSHYHQTIEHLVAKIYQSQWEFNQIVCLARGGLRVGDTLSRIFSKPLAILATSSYGDIKGQKQGNIKIAKSLTMTTDSLGSHVLLVDDLVDSGITIKESINWLQNNYGQEIKEVKTAVLWYKSCSIFEPDYYVDYLLDNPWIHQPFEIYEQINPSDLTNVYIDSQINLD
>NC_008312.1|WP_011612416.1|4495868_4496225_+|hypothetical-protein
MSTSKLTLNLVEGSISFDFTPEAARNLQSAIAELIKQLKSVAAKTATGSSGKPTPQKPTEYRYTGDVFLEIFCNPNIWPSPFAAKLLITLRDERIRITTEAELTRVYDDINQYLDQRG
>NC_008312.1|WP_011612418.1|4498809_4500057_+|hypothetical-protein
MELITNSNVYQEYQLSKFDLEMGVWPYYGVINWYKHQIDSHRLKVAIQQIVDSVPILGGRLVKKFFSPLKVVCNPQKSGVGFIHIDLDEQEINIDNLLDARTYIKNQFNIPKKSADAINKDIPLIYVILNHNQNYYGVTLLVNHFIADGGTYFKLLEYLSQAYEDLEYVSKSEPLFTINFNKMDDFISASFKKLSWKDKLFSSTSFIVFILNSFFQNKNNWSYLECILTKEKLDLIKGKNKNISNEKSAYSTNDALFEFLSVVPIKRFIFPCNLRYRKVGIPENYLGNAEAFVLDLTKPENNYMLKHTNVRKAVNQLPKIYSFIPTFNGKYMAHNSWVKLQNNLPGFGGKLILQKIFEFDDIPKDILSLFCKSSLIYRLTENEYLLIYINLKNVVLQVKNKLISLGVERVIIKQS

Crispr_ID: NC_008312_37

• CRISPR_ID: NC_008312_37
• CRISPR_location: 4605178-4605259
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NC_008312_37

Consensus_repeat	Method
GCCCCTAACCGTTATCTCATATT	CRISPRCasFinder

spacers of NC_008312_37

>37.1|4605201|36|NC_008312|CRISPRCasFinder
GGAATATTTTCAGTCTGTTCCTAGACATGTGCTTTA

CRISPR arrays and Neighbor proteins around NC_008312_37

CRISPR arrays

The CRISPR arrays of NC_008312_37

>merge|NC_008312|37|4605178-4605259|CRISPRCasFinder
GCCCCTAACCGTTATCTCATATTGGAATATTTTCAGTCTGTTCCTAGACATGTGCTTTAGCCCCTAACCGTTATCCCATATT

>NC_008312|37|31|4605178-4605259|CRISPRCasFinder
GCCCCTAACCGTTATCTCATATT	GGAATATTTTCAGTCTGTTCCTAGACATGTGCTTTA
GCCCCTAACCGTTATCCCATATT

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_008312.1|WP_011612482.1|4614965_4618961_-|non-ribosomal-peptide-synthetase	unknown	unknown	gnl|CDD|237108
NC_008312.1|WP_011612468.1|4578904_4581265_-|FkbM-family-methyltransferase	unknown	unknown	gnl|CDD|211387
NC_008312.1|WP_155994658.1|4591369_4591930_-|IS630-family-transposase	unknown	unknown	gnl|CDD|315923
NC_008312.1|WP_011612471.1|4588812_4590948_+|tetratricopeptide-repeat-protein	unknown	unknown	gnl|CDD|276809
NC_008312.1|WP_011612476.1|4596039_4596972_-|GTPase-Era	unknown	unknown	gnl|CDD|234624
NC_008312.1|WP_155994699.1|4622977_4624069_-|hypothetical-protein	unknown	unknown	gnl|CDD|165707
NC_008312.1|WP_044136829.1|4619068_4620037_-|NAD(P)-dependent-oxidoreductase	unknown	unknown	gnl|CDD|224995
NC_008312.1|WP_011612479.1|4609990_4610869_+|fructosamine-kinase-family-protein	unknown	unknown	gnl|CDD|367711
NC_008312.1|WP_011612470.1|4584743_4585874_+|glycosyltransferase	unknown	unknown	gnl|CDD|133055
NC_008312.1|WP_081432458.1|4605414_4605516_-|hypothetical-protein	unknown	unknown	unknown
NC_008312.1|WP_011612474.1|4593895_4594963_-|ABC-transporter-permease	unknown	unknown	gnl|CDD|224094
NC_008312.1|WP_155994698.1|4612246_4613242_-|methyltransferase-domain-containing-protein	unknown	unknown	gnl|CDD|366359
NC_008312.1|WP_011612473.1|4592698_4593613_-|class-I-SAM-dependent-methyltransferase	unknown	unknown	gnl|CDD|379312
NC_008312.1|WP_011612472.1|4591986_4592442_-|helix-turn-helix-domain-containing-protein	unknown	unknown	gnl|CDD|379267
NC_008312.1|WP_044137568.1|4621710_4622748_-|D-alanine--D-alanine-ligase	unknown	unknown	gnl|CDD|224102
NC_008312.1|WP_011612477.1|4597744_4598206_+|hypothetical-protein	unknown	unknown	unknown
NC_008312.1|WP_011612469.1|4581355_4582321_+|tetratricopeptide-repeat-protein	unknown	unknown	gnl|CDD|274350
NC_008312.1|WP_011612484.1|4620564_4621650_-|D-alanine--D-alanine-ligase	unknown	unknown	gnl|CDD|234948
NC_008312.1|WP_155994697.1|4605830_4605956_+|hypothetical-protein	unknown	unknown	gnl|CDD|372649
NC_008312.1|WP_011612478.1|4606541_4607075_-|hypothetical-protein	unknown	unknown	unknown

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_008312.1|WP_011612482.1|4614965_4618961_-|non-ribosomal-peptide-synthetase	gnl|CDD|237108	PRK12467, PRK12467, peptide synthase; Provisional.	0
NC_008312.1|WP_011612468.1|4578904_4581265_-|FkbM-family-methyltransferase	gnl|CDD|211387	cd11301, Fut1_Fut2_like, Alpha-1,2-fucosyltransferase. Alpha-1,2-fucosyltransferases (Fut1, Fut2) catalyze the transfer of alpha-L-fucose to the terminal beta-D-galactose residue of glycoconjugates via an alpha-1,2-linkage, generating carbohydrate structures that exhibit H-antigenicity for blood-group carbohydrates. These structures also act as ligands for morphogenesis, the adhesion of microbes, and metastasizing cancer cells. Fut1 is responsible for producing the H antigen on red blood cells. Fut2 is expressed in epithelia of secretory tissues, and individuals termed "secretors" have at least one functional copy of the gene; they secrete H antigen which is further processed into A and/or B antigens depending on the ABO genotype. O-fucosyltransferase-like proteins are GDP-fucose dependent enzymes with similarities to the family 1 glycosyltransferases (GT1). They are soluble ER proteins that may be proteolytically cleaved from a membrane-associated preprotein, and are involved in the O-fucosylation of protein substrates, the core fucosylation of growth factor receptors, and other processes.	6.34783e-27
NC_008312.1|WP_155994658.1|4591369_4591930_-|IS630-family-transposase	gnl|CDD|315923	pfam13358, DDE_3, DDE superfamily endonuclease. This family of proteins are related to pfam00665 and are probably endonucleases of the DDE superfamily. Transposase proteins are necessary for efficient DNA transposition. This domain is a member of the DDE superfamily, which contain three carboxylate residues that are believed to be responsible for coordinating metal ions needed for catalysis. The catalytic activity of this enzyme involves DNA cleavage at a specific site followed by a strand transfer reaction.	1.95952e-17
NC_008312.1|WP_011612471.1|4588812_4590948_+|tetratricopeptide-repeat-protein	gnl|CDD|276809	sd00006, TPR, Tetratricopeptide repeat. The Tetratricopeptide repeat (TPR) typically contains 34 amino acids and is found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi, plants, and humans. It is present in a variety of proteins including those involved in chaperone, cell-cycle, transcription, and protein transport complexes. The number of TPR motifs varies among proteins. Those containing 5-6 tandem repeats generate a right-handed helical structure with an amphipathic channel that is thought to accommodate an alpha-helix of a target protein. It has been proposed that TPR proteins preferentially interact with WD-40 repeat proteins, but in many instances several TPR-proteins seem to aggregate to multi-protein complexes.	2.20528e-21
NC_008312.1|WP_011612476.1|4596039_4596972_-|GTPase-Era	gnl|CDD|234624	PRK00089, era, GTPase Era; Reviewed.	1.2873e-151
NC_008312.1|WP_155994699.1|4622977_4624069_-|hypothetical-protein	gnl|CDD|165707	PLN00139, PLN00139, hypothetical protein; Provisional.	7.29101e-14
NC_008312.1|WP_044136829.1|4619068_4620037_-|NAD(P)-dependent-oxidoreductase	gnl|CDD|224995	COG2084, MmsB, 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases [Lipid metabolism].	1.20938e-60
NC_008312.1|WP_011612479.1|4609990_4610869_+|fructosamine-kinase-family-protein	gnl|CDD|367711	pfam03881, Fructosamin_kin, Fructosamine kinase. This family includes eukaryotic fructosamine-3-kinase enzymes. The family also includes bacterial members that have not been characterized but probably have a similar or identical function.	4.3425e-176
NC_008312.1|WP_011612470.1|4584743_4585874_+|glycosyltransferase	gnl|CDD|133055	cd06433, GT_2_WfgS_like, WfgS and WfeV are involved in O-antigen biosynthesis. Escherichia coli WfgS and Shigella dysenteriae WfeV are glycosyltransferase 2 family enzymes involved in O-antigen biosynthesis. GT-2 enzymes have GT-A type structural fold, which has two tightly associated beta/alpha/beta domains that tend to form a continuous central sheet of at least eight beta-strands. These are enzymes that catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. Glycosyltransferases have been classified into more than 90 distinct sequence based families.	8.4291e-34
NC_008312.1|WP_011612474.1|4593895_4594963_-|ABC-transporter-permease	gnl|CDD|224094	COG1173, DppC, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism].	5.03383e-87
NC_008312.1|WP_155994698.1|4612246_4613242_-|methyltransferase-domain-containing-protein	gnl|CDD|366359	pfam00891, Methyltransf_2, O-methyltransferase. This family includes a range of O-methyltransferases. These enzymes utilize S-adenosyl methionine.	1.31991e-35
NC_008312.1|WP_011612473.1|4592698_4593613_-|class-I-SAM-dependent-methyltransferase	gnl|CDD|379312	pfam13649, Methyltransf_25, Methyltransferase domain. This family appears to be a methyltransferase domain.	2.99084e-25
NC_008312.1|WP_011612472.1|4591986_4592442_-|helix-turn-helix-domain-containing-protein	gnl|CDD|379267	pfam13565, HTH_32, Homeodomain-like domain.	4.10583e-10
NC_008312.1|WP_044137568.1|4621710_4622748_-|D-alanine--D-alanine-ligase	gnl|CDD|224102	COG1181, DdlA, D-alanine-D-alanine ligase and related ATP-grasp enzymes [Cell envelope biogenesis, outer membrane].	6.57097e-36
NC_008312.1|WP_011612469.1|4581355_4582321_+|tetratricopeptide-repeat-protein	gnl|CDD|274350	TIGR02917, TPR_domain_protein, putative PEP-CTERM system TPR-repeat lipoprotein. This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.	2.28539e-22
NC_008312.1|WP_011612484.1|4620564_4621650_-|D-alanine--D-alanine-ligase	gnl|CDD|234948	PRK01372, ddl, D-alanine--D-alanine ligase; Reviewed.	4.56364e-33
NC_008312.1|WP_155994697.1|4605830_4605956_+|hypothetical-protein	gnl|CDD|372649	pfam13613, HTH_Tnp_4, Helix-turn-helix of DDE superfamily endonuclease. This domain is the probable DNA-binding region of transposase enzymes, necessary for efficient DNA transposition. Most of the members derive from the IS superfamily IS5 and rather fewer from IS4.	2.3955e-05

Protein sequences

>NC_008312.1|WP_011612477.1|4597744_4598206_+|hypothetical-protein
MKKFSTLLGSLCALVVANLPLPALAIPSDFDYKSNPEEYHPLPDLSIPYRTLPRKFDFPIITEIEIDNNVRTDNPITDAFVNTLPSIPTGITLDELLRYRAEYTAAIEAWGEEVTECLNQKPRLLRVSTGNPVIINGTEGTIVLNANNRAICK
>NC_008312.1|WP_011612476.1|4596039_4596972_-|GTPase-Era
MELSTNITIPVAPAGYKSGFVGIIGRPNVGKSTLMNQLVGQKVAITSPVAQTTRNRLRGILTTQAAQIIFVDTPGIHKPQHQLGKVLVQNAKVAIQSVDLVLLIVDGSVIAGGGDRYIINLLDKIQTPVILGMNKLDLQPQDAWKIEASYYQLIHPHPWQIIKFSAVTGEGVEILQDLLIEQMETGPYYYPPDLVTDQAERFIMGELIREQILLLTREEVPHSVAIAIDRVDEEPTITRILATINVERSSQKGILIGKGGNMLKAIGSAARQQIQKLIAGKVYLELFVRVQSKWRQSRIQLAELGYQVEE
>NC_008312.1|WP_011612474.1|4593895_4594963_-|ABC-transporter-permease
MKWWKNLKKNPLAKFGGLLLLIFYLVVIAADFIAPYDAYTSQPNGSLLPPTQIYWQNQAGEFIGPHVYPTTQGPVDLETGLRELKVDLSKPSPLGLFVQGPSYKLLGILPWNRHLFGTIGQAKFNLLGTDEQARDQFSRLIFGGRISLFIGLVGITIYFPLGMIIGGISGYFGGWIDSILMRFAEVLMTIPGIYLLVALAAILPPGLTSAQRFLLIVVITSFISWAGLARVIRGEVLSIKEREFVQAVRAMGAGSFYIIVRHVLPQTATYVIISATLAIPSFIISESVLSLIGLGIQQPDPSWGNMLSLATNASILVLQPWLVWPPALLIILTVLAFNLLGDGLRDALDPRNLQQ
>NC_008312.1|WP_011612473.1|4592698_4593613_-|class-I-SAM-dependent-methyltransferase
MTTTLKYQQNLATKLVNGILSIKPLANFAKTQARKMIIKRAEKIGIPWRQQVKELSKHNWDREWKVVNNPNLGYPKYYLTSFHAYEKGNMSWQAATEVEVASLAVHAGIWPEEGIGGDARLRQSFLDILKAEISTPKDVLDLGCSVGLNTFPLQKLFPEAQFTGVDLSPYFLAVALYRSQQQNLDINWVHAAAEATGLPDDSFDLISIFLVCHELPQFATRKIFREARRLLRSNGTIAIMDMNPKSEVYTTMDPHIFTLLKSTEPYLDEYFTLDIERELVDAGFEPPKIICNTHRHRTIIAIVV
>NC_008312.1|WP_011612472.1|4591986_4592442_-|helix-turn-helix-domain-containing-protein
MSGVVKIEINESVETLKKLLKSASTAQEKERLQTIYWLKTQTVETVKEIAIMLGRNRVTVQKWLGKYRTGGLNLLLEPKKNLGGRPSSIPPNVIEKLEAELQNPEGFQSYGEIQQWLTTCFDIELSYRTVHQLVRYKLKSKLKVPRPNHIK
>NC_008312.1|WP_155994658.1|4591369_4591930_-|IS630-family-transposase
MKLINKYSENQLPIRYWCQDETRIGLKTITGKVITACGVKPIGLYQWLFKYLWLYGLVEPKTGDSFFYEFSHLDTPCFERFLELFSQTYPEEIHIIQLDNGRGHLGNDLSIPDHIILLFQPPYCPEVNPIERLWKEVKKFLKNRVFDSLDFLRRILRNILTGFSQKDIASCTGYDFILEALCVVGL
>NC_008312.1|WP_011612471.1|4588812_4590948_+|tetratricopeptide-repeat-protein
MNLSKTAILTLTALSSQNLATEAKVTPNTNPYFQTTAPENINLTNSINVITVPSTKSISPPEILVSQAYNNLNLKTTLSTPNIHQIKRTLNNSWLGKIVKFSAKNNYQFQQFAEQMALKTDLESEASLNLNPTLTLLNTLLLVATLLPPITIGFFWLIRRLVIKELVGEVNKRLTKISQLELSLNQSQKLFTELESHIVTAKQSIDFLHQEAKISKSSVEQIEVLKSQFLMQLQVIISEAQEAKHQAIQEINYSVNSETKSVKNTQKLKSSEKQPTMIADDYFKLGEKQFYDGQYNQALANFEKAISLNSYLSEAWFKSGNVFVKLHRYSDALAAYDHAIAIHSDRFEYWFNRGNVFVKLERYSEALASYDKALSLNQNHVEIWLNRGILFRKLQRYNEAVVSYQKAILIQPKNVDILHNLGALLGKLERYEEAITTFDQALKIQPNKFEIWYNRGNLLGRIQSFNEAINSYDKALKIKPDRYEIWYNKGAILWQIEKYQEAVNCYDQAINLMPDDYEVWHNRGVALGALEKYQKAVNSYDKAIKIYPQCYQAFIGKAETLLKLEQYEEALSSCNHAIAIKKERYEGWLCQGRVLEKLTSYEEALMAYDQTIAINDNSYEAWARKGMVLEKIKRYQEALMCYDRAIAIKPNDSESQLKRRKLLSELQTEGIFTEANKYNLQLNLDVSNNQDKKLKKNQKNYPYLAQKGRKS
>NC_008312.1|WP_011612470.1|4584743_4585874_+|glycosyltransferase
MPINNFPKVTVCLPTYNSGEFLRYAIDSILEQTFTDFELIISDDCSTDNTPEIIRSYLEKDSRIQYLQNSHNLGLFPNWNRCLESASGEYITVFAQDDVMLPKNLEQKVKILEKYQNVGLVTSSIMVVDSDNNYLNWDWANYDEDSLVNGEEWVKKNLGKANPICCPFVLIRRYILEKVGGKFNDNYLFAGDLELWLRIALVADLYFVKEILGYYRWHKENKTHSFNDFDQVKEHLQICSNLIDSLNLSDLELNYWETEVLSRTVKWVSYYRIYRHLEISNFDEALKLCELLESWRGRSGKLGISVQELGTRIQKILQVNSRLHSEINEYSTWVNNLEGKNSALEREKSWLESQVKAWMQTAQKYYHKIKESGNCL
>NC_008312.1|WP_011612469.1|4581355_4582321_+|tetratricopeptide-repeat-protein
MNVLEKQQKAAEYLARGEFDLAIALCHQIIEVKPDFILAYQTIGNAWEIQGNLEAAMSWYAQALKIQPNNPELYKITGNLYSRKKQWDEAIAYYEKAIKLEPSLTEVYEKLGHIFKQRYQENLQAALNNYRQAIEYSPGDESNYYKILEIQPYHPEICRKLANTLLSKNKLGTAIIFYQIALITEPENSEIHFNLGKLLTTQGYLFEAISEYKLALEVEKNNPDIYLQLGIVLAKQERWSEAIASYRRTIEINPNLDSAYNYLGEILTKVGELEEGIYMFQKAININPNSYLFQKNLGDALAKQGKIDEASVAYSRAIELG
>NC_008312.1|WP_011612468.1|4578904_4581265_-|FkbM-family-methyltransferase
MKLDLRNLFTQNSVVPKGIIHVGAYDGKDIKLYENLSISKILFIEANPIVFEKLKANIATASIDVQAVNYAISNQNGKVRLYVNSMEQNSSIFPLKYYRDIYPNIKEAHQLIVEAKTLDTLLQELELSPKDFNILNLDIQGAELLALQGATNLLKYIDAVYTKVNYEELYEGCALAEKIDEFLAQTGFSRVAIAKPFHPSWGNAFYVRKQVVTMSTFGKNGGFGNQIFQYAFLKIYAQENRLSVEIPKWLGQHLFGHKDREIHEYLPVVVENNNEIFPGNREIWKNVDIQGYFLYHTSYYRNHKEYFCSLFQPVAEIETLVKVAWEKLRSLGKTIIGLHLQLHSDENNNSVVAPNEWYKIWLHGLWETLEEPVLFIASDNIEEINKGYFAEYNPITVRDLEVEVNLEYLNFFLLSKCDFVAISNTAFAFGACLLNQTGKYFFRPHFSTAKLIPFEPWNSTPVFRDIDIDEVGKSVLSEAQFRQIQSQLQQTQTNLENSQYQTNELSQKLVSTQSQLEQNQTELETIQYQRDQILGELEKFHCQLQQNQEKAKNAESELQKTREKLENTQSQRDEISQQLTSTQSQLQQNQEKAKNAESELQKTREKLENTQSQRDEISQQLTSTQSQLQQNQEKAKNAESELQKTREKLENTQSQRDEISQQLTSTQSQLQQNQEKAKNAESELQNIKTELDKSHSELHDIREELEITQFQLDEVQAELEQSQSQLSKHQEQLNTYQSQLKQTKKELETTKLKQENQEKILLNKNTKNYAAHIKNLAKILAETIQD
>NC_008312.1|WP_081432458.1|4605414_4605516_-|hypothetical-protein
MSTKFRKWQQHGVWEEINHTLRRETRVQETRHP
>NC_008312.1|WP_155994697.1|4605830_4605956_+|hypothetical-protein
MGGGRKAGLLEPQDKLFFILFYFKCYPNFEVAELLFNLDRN
>NC_008312.1|WP_011612478.1|4606541_4607075_-|hypothetical-protein
MTDQELKAVKLDLSTVHFILTRLEQGSCRTDRPALINECNRRAHFEEKLRNVLYAWDIKDQLVFYFSGHEDIRKNHLYCLKIGLKDSHWYPFNNLMNDVSAEEFQRAILVLDTWHNSAIIPGIKNSNDSISNIKESMENSKIPKVIAMITSSQKAQKSHELSYRSYSVFTDLFCNPI
>NC_008312.1|WP_011612479.1|4609990_4610869_+|fructosamine-kinase-family-protein
MWKKIAEHITQVTVENFEVTDHCLVGGGCINTAYKLTDGTRSYFVKINQASLVEMFRAEALGLEEMWETQTIRVPKPFCYGTEGNNCYIVLEWLELGDRGNDKSWENMGQNLAALHRHQGKSEFGWAHNNTIGSTPQINSWCGDWAEFWVQHRIGYQLKLAKGRGVSFSGGDRLLKIIPELLAGHQPQPSLVHGDLWGGNASFTVDGEPIIFDPATYWGDREVDLAMTELFGGFPTAFYRGYNEAWPLDNGYKHRKALYNLYHILNHFNLFGGGYASQAEIMIQQLLAKNWV
>NC_008312.1|WP_155994698.1|4612246_4613242_-|methyltransferase-domain-containing-protein
MIYGYWQSQCVYTATNLGIPNLLHYGPQTVEIIAEKTGTKSEKLYVVLRALAHLGIFVEKPGRVFAATELSELLMTDDSPSIGHFLMHITEPNMWDSWRELESGLKTGEVPFKIAKGQDFYTSYMTENPQSKNLFNNAMSFLTAEAVDPLFEVYNFSRFKTVMDIGGNQGTLIANIVKKFGCQGILFDLPHEVETAPNNISKYGVLDSVKIIGGSALESLPKGADAIIMKYFLSVFNQEDSIKVLTNCREALPQDGRVILLQTLVPSLGAPVEYPDGTIPALAAVQMMITNPGGYWRTEEEYKNLFAASGFKLEQVVYTGTSLTVMEFSPC
>NC_008312.1|WP_011612482.1|4614965_4618961_-|non-ribosomal-peptide-synthetase
MNYQGISTLISPSTSHIQQANWFLYKFNPTGLADKISIAIQMVNSVDIPTVKNTLQILMKRHSILRSVYSEKDGNIISQIRENVEIDWEKIDAYSWNNIELNEQLSARMRLPFNLETGGVFRACLFCISATENILLLTLHQIAGDRYSISILVDEFVTIYESKINNTNSNLIPINTNYVNYINEELEFINSSEGKQIGDYWQEKLGGELPILELPTNFSRPSIRTYNGTALKSTINFQLNQKIQQLAKTLEVKKEEIILAVFKVLLYRYTGEEDILVGLLQSRENQPLFEQVVGNFTNITVLRNLISGNIKFTDFLNQVSKNIFEVENYQNYPYSLLIKQLKSANLSHYPICQVAFSYHKFHKLFEAKELELEYYELPQQKVDFELNLEIIELPESLLANFKYNSDVLEAQTVAQIAEHFQNLLTAVVENPETPVGKLSMLSEREKQKILIAWNETKTDYPQDISIHQLFESQVEKTPDAIAVVFESEKLTYSELNNKANQLAHYLQKLGVKPKAHLGICVERSLSMVIGILGILKAGAAYVPLDSSYPSERLAYMISDAQVSVLLTQESLLTSLPKHQAQVVCLDRDWKGIKEFSTVNLSSGVTPENLGYIIYTSGSTGKPKGVAMSQRALVNLIMWQQEEATVGQGAKTLQFTPISFDVSFQEIFSTWYSGGTLVLVSQEVRRDSFALMAFMVESQIERIFLPFVALQQLATVAPQCQVLPPFCEIVTAGEQLQVTPDLVALMNRLPNCKVQNQYGPSESHVVSAYTLQGAATNWPKLPPIGRPIANNQLYIFNTDLQPIPIGVSGELYIGGVGVANGYLNRPDLTVEKFITIEGNKEQGIGNRLYKTGDLARYLSDGNIEFLGRIDNQVKIRGFRIEIGEIETTLSQHPIVKETVVLLREDKPGNKLLVAYIVPETEGAQNVVPQLKQYLKEKLAEYMVPSAFVVLSKLPLTPSGKVNRRALPAPDISSFSQSDNFVAPRDRIEQQLAQMWSEILNIHPVGVKSNFFELGGHSLLAINLMAKIQESFGQQLPLSTLFTNRTIEDLGRLIRGESQVSSSSIVPLQTQGNKQPFFCIHPAGGHVFYYHDLSHYLGNNQPFYGIQAQGFNEGEKIFTNVEDMAEFYVQTLLEFQPDGPYQIGGWSFGGVVAFEMGQQLLQQGKEVSLLALLDPWVPILLDPNKKIDNLYMKGVLSRYFGGMFGITDLVTEDELLGLKSEEQIEFIIDKAEKLKLFPKEATREQNRRFIDVIIGTLKATYTYKRHPYPGKVTVFRAQEKHPHGIDPQLVWVEMYAILDVADIEVVMVPGNHFTFIKESNNKVLAECLSEHLK
>NC_008312.1|WP_044136829.1|4619068_4620037_-|NAD(P)-dependent-oxidoreductase
MSPSKNTSETNPPLNYPTLGIIGCGNIGGRQAANFIAQGYPVYVYDINLDRMTELESLGAHITHSCAELATYSDVIFTSLPTPADVVRAVLEGDGNLSQGLRSRSIYIDITTNSPETIFKLSKAMEELGVEMLDAPFNDCPEGAKSDGGMGLAVMASGSRKTFERVEPILQLMADRVIYCGTLGNGTRCKLIHNAVNAVAVQAVTEGITLGLAQGIPLETIWDALRFGAFGQNAGDIHGLPHYWFSRRCDDLSQHPDFTVKLLHKDLQLALEMASQQNISVPQFSLTVKDYEEAVRRGFSDYSTTKVRCLQEEQARVMAKTT
>NC_008312.1|WP_011612484.1|4620564_4621650_-|D-alanine--D-alanine-ligase
MKLEEINQNQHSSLATMNRLQVLHLAGSRVSEFYYNLSILYAKEVVQPVGVSSYYAVVHPDGLWQLGASLDSLSEKMLLQDMILQLPQIDVVVPHMFCFLGMTSFRAFFEDMLNLPLVGSPSYCTALATNKAQTRNVVSASGVQVAKAQQLRRGETLTMKPPFVVKPTSEDNSLGVTLVWDESQIEAALDKGFELEDKLLVEDYIPGRELRVAVVERKGELQVLPMIEYLVTEEHPIRTVNDKLVLQSDGTPEKQPEKPIAKPICPANVTPELFEKLANAAKSAHIALGCRDYSLYDFRVHTNTNEPYFLEAGLFWTFGKIAMISRMLQADGESLEDVALELWSAAAGRTRVACGSLFKWN
>NC_008312.1|WP_044137568.1|4621710_4622748_-|D-alanine--D-alanine-ligase
MNRLQVLHLAGSRVSEFYYNLSILYAKEVVQPVGVSSYYAVVHPDGLWQLGASLDSLSEKMLLQDMILQLPQIDVVVPHMFCFLGMTSFRAFFEDMLNLPLVGSPSYCTALATNKAQTRNVVLASGVQVAKAQQLGRGETLTMKPPFVVKPTSEDNSLGLTLVWDESQIEAALDKGFELDNKLLVEDYIPGRELRVAVVERESKLSVLPMIEYLVTEEHPIRTVHDKYVLQSDGTPGKQPEKPIAQPICPANVTPELFEKLVNAAKNAHIALGCRDYSLYDFRVHAETNEPYFLEAGLFWGFGKISMISRMLQADGQSLEDVSLELWSAAAGRTRVACGSLFKWN
>NC_008312.1|WP_155994699.1|4622977_4624069_-|hypothetical-protein
MEKLPNYLSSNIKLRFLRDEEKSFTTGEKKLPLVIEPVQKKSFSVLAELVRENRDWFHRQQDNYGALLFRGFEIETAAQFENILELLNVKLASKYHFGSSQRNRITDKVFTSSEAPGNLIIPPHNELNMVPVRPMCLAFFCQIEPTLYGETPIINTEKIFNELSPNLQHKFANTPQKFVRNVPNHLLGIVFEELSREEITKMLEDGEFYFEWKADGSLYFECSYIPVFHHPRTGKLCFCLSTFDSFVAREWYRSIAQRYPFKEIIYYNFLPSKLYRNLEGIDNAQPKMYLVNEEGNNTKITEAEAKELGEAEWKNATVFPWRQGDILVIDNLQVVHGRLNVQPPRKILTAFGNMCNIRDMKKK

Crispr_ID: NC_008312_38

• CRISPR_ID: NC_008312_38
• CRISPR_location: 5739022-5739126
• CRISPR_type: Unclear
• Repeat_type: NA
• Spacer_info: 1 spacers
• Cas_protein_info: cas3

Consensus repeat of NC_008312_38

Consensus_repeat	Method
GCTAGTAAATATTAGCAGTTTTTGTCTGACCAAT	CRISPRCasFinder

spacers of NC_008312_38

>38.1|5739056|37|NC_008312|CRISPRCasFinder
AAAGCATCAACTACTTTGTCTATTTATCCTAGCTAAA

CRISPR arrays and Neighbor proteins around NC_008312_38

CRISPR arrays

The CRISPR arrays of NC_008312_38

>merge|NC_008312|38|5739022-5739126|CRISPRCasFinder
GCTAGTAAATATTAGCAGTTTTTGTCTGACCAATAAAGCATCAACTACTTTGTCTATTTATCCTAGCTAAAGCTAGTAAATATTAGCAGTTTTTGTCTGACCAAT

>NC_008312|38|32|5739022-5739126|CRISPRCasFinder
GCTAGTAAATATTAGCAGTTTTTGTCTGACCAAT	AAAGCATCAACTACTTTGTCTATTTATCCTAGCTAAA
GCTAGTAAATATTAGCAGTTTTTGTCTGACCAAT

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_008312.1|WP_071820702.1|5745245_5745491_-|DUF1049-domain-containing-protein	unknown	unknown	unknown
NC_008312.1|WP_155994713.1|5737923_5738106_+|hypothetical-protein	unknown	unknown	gnl|CDD|270891
NC_008312.1|WP_155994480.1|5747935_5748073_+|hypothetical-protein	unknown	unknown	unknown
NC_008312.1|WP_011613117.1|5717511_5719536_+|VacB/RNase-II-family-3'-5'-exoribonuclease	unknown	unknown	gnl|CDD|223631
NC_008312.1|WP_155994715.1|5740483_5740588_+|hypothetical-protein	unknown	unknown	gnl|CDD|315923
NC_008312.1|WP_011613120.1|5730127_5731453_-|30S-ribosomal-protein-S12-methylthiotransferase-RimO	unknown	unknown	gnl|CDD|273453
NC_008312.1|WP_011613119.1|5726338_5727826_-|DEAD/DEAH-box-helicase	cas3	cd09639_cas3_CAS-I	gnl|CDD|223587
NC_008312.1|WP_155994714.1|5740029_5740167_+|hypothetical-protein	unknown	unknown	gnl|CDD|379282
NC_008312.1|WP_011613129.1|5747002_5747629_-|precorrin-8X-methylmutase	unknown	unknown	gnl|CDD|180325
NC_008312.1|WP_011613123.1|5736616_5736991_-|DDE-transposase-family-protein	unknown	unknown	gnl|CDD|372649
NC_008312.1|WP_155994479.1|5727948_5728101_+|hypothetical-protein	unknown	unknown	unknown
NC_008312.1|WP_011613118.1|5722163_5722937_-|1-(5-phosphoribosyl)-5-[(5--phosphoribosylamino)methylideneamino]imidazole-4--carboxamide-isomerase	unknown	unknown	gnl|CDD|179108
NC_008312.1|WP_011613122.1|5733995_5734433_+|NUDIX-hydrolase	unknown	unknown	gnl|CDD|239217
NC_008312.1|WP_011613127.1|5743981_5744932_+|hypothetical-protein	unknown	unknown	unknown
NC_008312.1|WP_011613131.1|5749798_5750809_+|tetratricopeptide-repeat-protein	unknown	unknown	gnl|CDD|276809
NC_008312.1|WP_044136905.1|5745007_5745214_+|hypothetical-protein	unknown	unknown	unknown
NC_008312.1|WP_011613121.1|5732788_5733697_+|OmpA-family-protein	unknown	unknown	gnl|CDD|143586
NC_008312.1|WP_011613116.1|5716919_5717138_+|30S-ribosomal-protein-S18	unknown	unknown	gnl|CDD|178997
NC_008312.1|WP_011613130.1|5748620_5749274_-|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl|CDD|213192
NC_008312.1|WP_011613128.1|5745693_5746383_+|hypothetical-protein	unknown	unknown	unknown

HMMScan for Signature genes

Protein	Cas_name	Cas_description	E-value	Identity	Coverage
NC_008312.1|WP_011613119.1|5726338_5727826_-|DEAD/DEAH-box-helicase	cas3	cd09639_cas3_CAS-I	2.6e-11	37.9	0.4

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_008312.1|WP_011613119.1|5726338_5727826_-|DEAD/DEAH-box-helicase	gnl|CDD|223587	COG0513, SrmB, Superfamily II DNA and RNA helicases [DNA replication, recombination, and repair / Transcription / Translation, ribosomal structure and biogenesis].	3.99503e-160
NC_008312.1|WP_155994713.1|5737923_5738106_+|hypothetical-protein	gnl|CDD|270891	cd13989, STKc_IKK, Catalytic domain of the Serine/Threonine kinase, Inhibitor of Nuclear Factor-KappaB Kinase (IKK). STKs catalyze the transfer of the gamma-phosphoryl group from ATP to serine/threonine residues on protein substrates. The IKK complex functions as a master regulator of Nuclear Factor-KappaB (NF-kB) proteins, a family of transcription factors which are critical in many cellular functions including inflammatory responses, immune development, cell survival, and cell proliferation, among others. It is composed of two kinases, IKKalpha and IKKbeta, and the regulatory subunit IKKgamma or NEMO (NF-kB Essential MOdulator). IKKs facilitate the release of NF-kB dimers from an inactive state, allowing them to migrate to the nucleus where they regulate gene transcription. There are two IKK pathways that regulate NF-kB signaling, called the classical (involving IKKbeta and NEMO) and non-canonical (involving IKKalpha) pathways. The classical pathway regulates the majority of genes activated by NF-kB. The IKK subfamily is part of a larger superfamily that includes the catalytic domains of other protein STKs, protein tyrosine kinases, RIO kinases, aminoglycoside phosphotransferase, choline kinase, and phosphoinositide 3-kinase (PI3K).	0.000250428
NC_008312.1|WP_011613117.1|5717511_5719536_+|VacB/RNase-II-family-3'-5'-exoribonuclease	gnl|CDD|223631	COG0557, VacB, Exoribonuclease R [Transcription].	1.80202e-124
NC_008312.1|WP_011613120.1|5730127_5731453_-|30S-ribosomal-protein-S12-methylthiotransferase-RimO	gnl|CDD|273453	TIGR01125, Ribosomal_protein_S12_methylthiotransferase_RimO, ribosomal protein S12 methylthiotransferase RimO. Members of this protein are the methylthiotransferase RimO, which modifies a conserved Asp residue in ribosomal protein S12. This clade of radical SAM family proteins is closely related to the tRNA modification bifunctional enzyme MiaB (see TIGR01574), and it catalyzes the same two types of reactions: a radical-mechanism sulfur insertion, and a methylation of the inserted sulfur. This clade spans alpha and gamma proteobacteria, cyano bacteria, Deinococcus, Porphyromonas, Aquifex, Helicobacter, Campylobacter, Thermotoga, Chlamydia, Streptococcus coelicolor and Clostridium, but does not include most other gram positive bacteria, archaea or eukaryotes. [Protein synthesis, Ribosomal proteins: synthesis and modification].	0
NC_008312.1|WP_155994715.1|5740483_5740588_+|hypothetical-protein	gnl|CDD|315923	pfam13358, DDE_3, DDE superfamily endonuclease. This family of proteins are related to pfam00665 and are probably endonucleases of the DDE superfamily. Transposase proteins are necessary for efficient DNA transposition. This domain is a member of the DDE superfamily, which contain three carboxylate residues that are believed to be responsible for coordinating metal ions needed for catalysis. The catalytic activity of this enzyme involves DNA cleavage at a specific site followed by a strand transfer reaction.	1.31535e-06
NC_008312.1|WP_155994714.1|5740029_5740167_+|hypothetical-protein	gnl|CDD|379282	pfam13592, HTH_33, Winged helix-turn helix. This helix-turn-helix domain is often found in transferases and is likely to be DNA-binding.	0.001269
NC_008312.1|WP_011613129.1|5747002_5747629_-|precorrin-8X-methylmutase	gnl|CDD|180325	PRK05953, PRK05953, Precorrin-8X methylmutase.	1.90188e-147
NC_008312.1|WP_011613123.1|5736616_5736991_-|DDE-transposase-family-protein	gnl|CDD|372649	pfam13613, HTH_Tnp_4, Helix-turn-helix of DDE superfamily endonuclease. This domain is the probable DNA-binding region of transposase enzymes, necessary for efficient DNA transposition. Most of the members derive from the IS superfamily IS5 and rather fewer from IS4.	3.22619e-18
NC_008312.1|WP_011613118.1|5722163_5722937_-|1-(5-phosphoribosyl)-5-[(5--phosphoribosylamino)methylideneamino]imidazole-4--carboxamide-isomerase	gnl|CDD|179108	PRK00748, PRK00748, 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase; Validated.	1.67895e-136
NC_008312.1|WP_011613122.1|5733995_5734433_+|NUDIX-hydrolase	gnl|CDD|239217	cd02883, Nudix_Hydrolase, Nudix hydrolase is a superfamily of enzymes found in all three kingdoms of life, and it catalyzes the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes belonging to this superfamily require a divalent cation, such as Mg2+ or Mn2+ for their activity. Members of this family are recognized by a highly conserved 23-residue nudix motif (GX5EX7REUXEEXGU, where U = I, L or V), which forms a structural motif that functions as a metal binding and catalytic site. Substrates of nudix hydrolase include intact and oxidatively damaged nucleoside triphosphates, dinucleoside polyphosphates, nucleotide-sugars and dinucleotide enzymes. These substrates are metabolites or cell signaling molecules that require regulation during different stages of the cell cycle or during periods of stress. In general, the role of the nudix hydrolase is to sanitize the nucleotide pools and to maintain cell viability, thereby serving as surveillance and "house-cleaning" enzymes. Substrate specificity is used to define child families within the superfamily. Differences in substrate specificity are determined by the N-terminal extension or by residues in variable loop regions. Mechanistically, substrate hydrolysis occurs by a nucleophilic substitution reaction, with variation in the numbers and roles of divalent cations required. This superfamily consists of at least nine families: IPP (isopentenyl diphosphate) isomerase, ADP ribose pyrophosphatase, mutT pyrophosphohydrolase, coenzyme-A pyrophosphatase, MTH1-7,8-dihydro-8-oxoguanine-triphosphatase, diadenosine tetraphosphate hydrolase, NADH pyrophosphatase, GDP-mannose hydrolase and the c-terminal portion of the mutY adenine glycosylase.	2.61729e-11
NC_008312.1|WP_011613130.1|5748620_5749274_-|ABC-transporter-ATP-binding-protein	gnl|CDD|213192	cd03225, ABC_cobalt_CbiO_domain1, First domain of the ATP-binding cassette component of cobalt transport system. Domain I of the ABC component of a cobalt transport family found in bacteria, archaea, and eukaryota. The transition metal cobalt is an essential component of many enzymes and must be transported into cells in appropriate amounts when needed. This ABC transport system of the CbiMNQO family is involved in cobalt transport in association with the cobalamin (vitamin B12) biosynthetic pathways. Most of cobalt (Cbi) transport systems possess a separate CbiN component, the cobalt-binding periplasmic protein, and they are encoded by the conserved gene cluster cbiMNQO. Both the CbiM and CbiQ proteins are integral cytoplasmic membrane proteins, and the CbiO protein has the linker peptide and the Walker A and B motifs commonly found in the ATPase components of the ABC-type transport systems.	9.69212e-61
NC_008312.1|WP_011613121.1|5732788_5733697_+|OmpA-family-protein	gnl|CDD|143586	cd07185, OmpA_C-like, Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA. OmpA-like domains (named after the C-terminal domain of Escherichia coli OmpA protein) have been shown to non-covalently associate with peptidoglycan, a network of glycan chains composed of disaccharides, which are crosslinked via short peptide bridges. Well-studied members of this family include the Escherichia coli outer membrane protein OmpA, the Escherichia coli lipoprotein PAL, Neisseria meningitdis RmpM, which interact with the outer membrane, as well as the Escherichia coli motor protein MotB, and the Vibrio flagellar motor proteins PomB and MotY, which interact with the inner membrane.	7.7561e-19
NC_008312.1|WP_011613116.1|5716919_5717138_+|30S-ribosomal-protein-S18	gnl|CDD|178997	PRK00391, rpsR, 30S ribosomal protein S18; Reviewed.	8.4039e-31
NC_008312.1|WP_011613131.1|5749798_5750809_+|tetratricopeptide-repeat-protein	gnl|CDD|276809	sd00006, TPR, Tetratricopeptide repeat. The Tetratricopeptide repeat (TPR) typically contains 34 amino acids and is found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi, plants, and humans. It is present in a variety of proteins including those involved in chaperone, cell-cycle, transcription, and protein transport complexes. The number of TPR motifs varies among proteins. Those containing 5-6 tandem repeats generate a right-handed helical structure with an amphipathic channel that is thought to accommodate an alpha-helix of a target protein. It has been proposed that TPR proteins preferentially interact with WD-40 repeat proteins, but in many instances several TPR-proteins seem to aggregate to multi-protein complexes.	1.02902e-06

Protein sequences

>NC_008312.1|WP_155994713.1|5737923_5738106_+|hypothetical-protein
MRVVNKYIACFKIYLLQIIHRDIKYKNIIRRSKNNKLLLVDFGYTKYPTTTAISKIGTAK
>NC_008312.1|WP_011613123.1|5736616_5736991_-|DDE-transposase-family-protein
MNKTLEYIHNYPKEIKRIIGITYEQLTQLIENAIIKESENFQVIAEKEIRLIKPGGGRKKTLTKTDEIFLTLYYLHHIPSFQLLGINFGVSESTANNIFHYWINILPDLLPASLLEQVKKKKMN
>NC_008312.1|WP_011613122.1|5733995_5734433_+|NUDIX-hydrolase
MTRKKPFSPEEFKLLYSQVPRLVVEVIVKTEIGVALTLRKDTAWNNLWHIPGGTVFYQEYIEDAIKRIAEEELSITVVKQKLLGYLEYPSEVKQRGFGWSVGLVFLCTTNSLLPSENQEGEKIQLFDYIPENIVEEHKNILNQLF
>NC_008312.1|WP_011613121.1|5732788_5733697_+|OmpA-family-protein
MSTEKQIDDQTDDQQVLGPIILTLFMGLMIICAWAFARPNAFKRPDIDVQLTENIDSENVNSQTEENQVTETLETETTKTTTIETKDAETTTTAKIIYKPSKVNIETTTSTKNPATDRTETTTSAQQPTANTNRIETRTSRDTEQPTTDKIETTTNTIESTAASQAKPETVSGQTDIVATSDSQEKYLTEAKTLGQIKFEINEVELSSPAKQTVNSLIPEINKYDPNRVTIKVEGHTSRVGDAQLNKEISQDRANVVVAYLKEKNLPHQVISEGMGYSQPLPNSNPASDINQRTVIILIPAN
>NC_008312.1|WP_011613120.1|5730127_5731453_-|30S-ribosomal-protein-S12-methylthiotransferase-RimO
MSTKPTIAFTHLGCEKNRIDTEHIIGLLVQAGYEVDANEELADYVVVNTCSFIQAAREESVKTLVELAEANKKIVIAGCMAQHFPEELLAELPEAIALVGTGDYHKIVDVMQRVEKGDRVKEVTAEPTYIADETTPRYRTTSEGVAYVRIAEGCDYRCAFCIIPHLRGKARSRTIESIVVEAQKLADQGVKEIILISQITTNYGIDIYGQPKLADLLEALGKVDIPWIRMHYAYPTGLTPKVITAIQDTPNILPYLDLPLQHSHPEILRAMNRPWQGQVNDDIIKRIKTAMPNAVLRTSFIVGFPGETEEHHSHLVEFVKRHEFDHVGVFTFSPEEGTPAYNLPNQLPQEVMDARRQEIMEVQQSISWQQNQKLVGQLVDVLIEQENPQTGELIGRSPRFSPEVDGLIYVKGEARLGCIVPVMITDADIYDLYGCLISSAA
>NC_008312.1|WP_155994479.1|5727948_5728101_+|hypothetical-protein
MNLIDKSIQVSCLSGCDVTLIQSLVPESPNLEADLPSTISDHKPLLTINY
>NC_008312.1|WP_011613119.1|5726338_5727826_-|DEAD/DEAH-box-helicase
MDLSFASLGISEERANHLETIGFTEPTPIQAQAIPPLLEGKDIVGQAQTGTGKTAAFSLPILEQIDIDTNAVQALILTPTRELALQVTEAIRQFTGINSKGPTKRRLFVLTVYGGQSIERQSQRLQKGVHIVVGTPGRIIDMLNRNSLKLDHLKMMVLDEADEMLSMGFIQDVEKILEAAPAERQTAFFSATMDYSIRKLVNKYLQSPVTVKVAQQKTTPKRITQTVYILPRGWSKGKALQPILELEDPEAALIFVRTRQAAAELTNQLQSAGHSVDEYHGNLNQSQRERLLTRFRNQQVRWVVATDIAARGLDVDHLTHVINYDLPDSVDSYVHRIGRTGRAGREGTAISLIHPVDKRKLRLIERHLRQRLNTRSIPKRSQIEARQLQKLQDKVRSALSGERMASFLPLISQLGKEYDPHAIAAAALQIAYDETRPAWMGLDYSQEEDEPMYETPKPRLKKQLPKKSNNKSYSDKNKNLKDEIYVEEASLPQNN
>NC_008312.1|WP_011613118.1|5722163_5722937_-|1-(5-phosphoribosyl)-5-[(5--phosphoribosylamino)methylideneamino]imidazole-4--carboxamide-isomerase
MNIIPAIDILGGRCVRLYQGDYKQTQIFNDNPVDVAKRWADEGATKLHLVDLDAAKVGQPVNQKTIEAIIKAVDIPIQVGGGLRNYSTVASLLALGVQQAILGTVAIEQPELVSDFCQKFPGQIIVGIDARDGKVATKGWLETSQVLATDLALQMAKLKVAAIIYTDIHRDGTLKGPNIEALRELATAVSIPVIASGGISSINDLLNLLALETIGVKGAIVGRALYTGGISLKEANQAVGQGRWQDVPPNLGSSTFV
>NC_008312.1|WP_011613117.1|5717511_5719536_+|VacB/RNase-II-family-3'-5'-exoribonuclease
MEKGKLIEFRLHGERRLAVADRPDGKKNWVVIEANGKSNSIPPKQISYEVGGESYQSSEIPQFIQEVKTYLDPSSLEVAWELLVEEAEAVNPEEMALLLFSEQTPIQCYAAYILLSDDKLYFKQKGDRYEPRSVAQVAEIKHQQEVQKQRKEELENFLLRVHNRLAGEKVEWEQSDYNRLDIIEKFATHGEETSHRSQAMETLATLKVPETSEAAFKLLVDLGIWSEHENLYLRRSQIPKCFSTKVLEVAKSCLQSLPPDPETNRLDLTHLKVYTIDDESTQEIDDGLSIEFLEDGQHRIWVHIADPTRLLIPGDELDLEARRRTTTLYLPTGMVPMFPPELATGPMSLIQGQVCRALSFGILLDESGAVIDYIIHASLIKPTYRLTYDDVDEMLQLKIKLEPEIHALNDWAKQRFKWRQSQGSISIYMPESVIKVKGEGEEITVEVLDDSPSRQLVAEMMILAGEVGAKYGQENNIPLPYRSQPQPELPPDAELMLLPAGPVRSTAMRRCMPKSEMGTIPARHASLALETYVQVTSPIRRYSDLLAHFQIKAHLRGDPLPFTLEQMQEMVMSLVPAVKEASSVERFTNRYWGLEYLRRNSGEVWQALVIRWLKEEINLGLVLLEELGLELAMRFGRSVEVGDRLEVKVAHADPRRDEIVFQEIVNNVAEKVNN
>NC_008312.1|WP_011613116.1|5716919_5717138_+|30S-ribosomal-protein-S18
MANYYRKRVSPIKPGDPIDYKDVELLKKYITERGKIMPRRITGLTSKQQRDLTKSIKRARLVALLPYVNKES
>NC_008312.1|WP_155994714.1|5740029_5740167_+|hypothetical-protein
MYLSYRTVHQLVRYKLKSKLKVPHPNHIKQNKEAQENFKKNSHLN
>NC_008312.1|WP_155994715.1|5740483_5740588_+|hypothetical-protein
MILLFQTPYFPEFNPIERLWKDVKKIWKNRSFNS
>NC_008312.1|WP_011613127.1|5743981_5744932_+|hypothetical-protein
MTPTKLSDSEKLEIIELYQTTQENTITLADRYGVSSSTIRRILQSSIPEYEYKELVQQKQKRPSRSPRNIGHDTEENLDESVDGGNLELEESGYRANEVDGMVKRRRRRSSSSSDAETEELTELPKLSLTSEYTEKSNNAFEGSYDSPTKEIQEILAVDLREKPQNLDDFENDDLEDFDEEFDDEDKDKLEGEVEVEEVVDTSYNISIQNSSYSEVKVYNLTEAVLPKICYLVVDKFTELVTKPLIAFGELGQIPVEESQKKTLPVFNNHRVAHRFSARNQRVLKVPDGRMLQKTTVYLQAKGITRLLIDGQVYKL
>NC_008312.1|WP_044136905.1|5745007_5745214_+|hypothetical-protein
MSAAYHFGDYLISLSVFPTEVKDLIASLGIKAGWSYLPIPYLEKGCNLKKDLLTFGGFDMRLDVFFQY
>NC_008312.1|WP_071820702.1|5745245_5745491_-|DUF1049-domain-containing-protein
MQKLIPPIISSIILALWVSSIAILSVQNATPISLKFLSFQSIEIPIGVILSFSVSIGVIISSIILPSLFHLEQIKDHQKNF
>NC_008312.1|WP_011613128.1|5745693_5746383_+|hypothetical-protein
MLVPLTRKTFEQLIPIVATGDQYKYYWGRLSEVLKRALISAVSVLVIVLINVLVHDDGDPLFLLVGITAGLYWFWGPVLLASFQNVELRRYPYSGLWQGKVFDVYLSEEVVGQEEKVNKKGELIIVENLEQRINLELQDKTGFKVEIQAPLRRYHQGISRGQIAVMLVMSYQQDLEKIAKYSDVYLPTVNLWVSNYPYLRKDVFVEVINQVRSSRRKNKQHQQPNFKFE
>NC_008312.1|WP_011613129.1|5747002_5747629_-|precorrin-8X-methylmutase
MEWHITDAQSLRIIDKEIGLHTLSPAEYEIVKRVIYATADFEYKSLVSFSEHALQSGAAALAARTTIVVDVPMLQVGITPVIQNTFVNPVYCSMDAITRPQKEKTTAAWGIETLARRYPEGIFVIGQAQTALCAIVDLIEADEIRPALVIGTPSGFVGVDVAKSRLYDSMIPHIRIDGRKGSAVVAVAIINGLVDLAWQAYGQKSPGN
>NC_008312.1|WP_155994480.1|5747935_5748073_+|hypothetical-protein
MTSLILKSKANSLPAPGIIILDKIYQIFYEVASGDIFARRRKSAN
>NC_008312.1|WP_011613130.1|5748620_5749274_-|ABC-transporter-ATP-binding-protein
MLHLKNLYYHPAASLIPILENINMELAPKEMGLIIGRSGSGKTTLLEILAGLAKCSQGEIYWREQKLTSENLQQLGGLVFQFPERHFCGSTILEELRLGHPELRLEQISSALEEVGLQELPLSTSPQALSGGQQRRLALAVQLIRQPHLLMLDEPTAGLDWSIRKQLVNLLAKLKNHWSLLVVTHDSSDLLSIADKYWILNKGHLEEKSQDKLEIKS
>NC_008312.1|WP_011613131.1|5749798_5750809_+|tetratricopeptide-repeat-protein
MLKTLFSWCKNFPVLKKISVFYSVTLVGFNFWVTPAIGDPFRKINPIEIGEKTEAAFEAMFEEGNYKEARDYLKIAECEEIGEPLIYAMISSLHYLDKNWDSLKLYAQKTTEVAENLIAIDPVRGNIYAATGYFLEGAYIISTEGTLKGAPKALEKLRKVLSHFESAERINSSDPELNLLKGYMDLMLAVNLPFSDISKAIEILENKAYPHHLAYRGLAVAHRDLDDFKKALQYVDKALSEVPENPEVHYLKAQILVAQAREKDNNLSLRKKAKKNFDKALAKSEQMPRRLVAQIFFEQCKNINNIDDRKRSCDSMRDIIRDGSGTWGPQELPALR

Crispr_ID: NC_008312_39

• CRISPR_ID: NC_008312_39
• CRISPR_location: 5774650-5774836
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 2 spacers

Consensus repeat of NC_008312_39

Consensus_repeat	Method
GGTGCTTCAGAAAATGAATGAATTAACTATTGCGCAATAGTTGGAA	PILER-CR

spacers of NC_008312_39

>39.1|5774700|47|NC_008312|PILER-CR
TCTATACGCAATAGTCAGAAAATTTCTAGACTCATCTCTGGTATCTT
>39.2|5774797|27|NC_008312|PILER-CR
TATATTATAACTTACCCCTGACATCGT

CRISPR arrays and Neighbor proteins around NC_008312_39

CRISPR arrays

The CRISPR arrays of NC_008312_39

>merge|NC_008312|39|5774650-5774836|PILER-CR
AATTAATTAACTATTGCTCTATACGCAATAGTCAGAAAATTTCTAGACTCATCTCTGGTATCTTGGTGCTTCAGAAAATGAATGAATTAACTATTGCGCAATAGTTGGAATATATTATAACTTACCCCTGACATCGTGGTGCTTCAGAAAATGAATGAATTAACTATTGCGCAATAGTTGGAAGACA

>NC_008312|39|2|5774650-5774836|PILER-CR
AATTAATTAACTATTGCTCTATACGCAATAGTCAGAAAATTTCTAGACTC	ATCTCTGGTATCTTGGTGCTTCAGAAAATGAATGAATTAACTATTGC
GCAATAGTTGGAATATATTATAACTTACCCCTGACATCGTGGTGCTTCAG	AAAATGAATGAATTAACTATTGCGCAA
TAGTTGGAAGACA

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_008312.1|WP_011613148.1|5792468_5793836_+|ATP-binding-protein	unknown	unknown	gnl|CDD|379062
NC_008312.1|WP_044136906.1|5770498_5770714_+|hypothetical-protein	unknown	unknown	unknown
NC_008312.1|WP_011613138.1|5764285_5766127_+|ATP-dependent-metallopeptidase-FtsH/Yme1/Tma-family-protein	unknown	unknown	gnl|CDD|273520
NC_008312.1|WP_081432485.1|5773772_5774021_-|SDR-family-oxidoreductase	unknown	unknown	gnl|CDD|379263
NC_008312.1|WP_081432561.1|5770703_5771591_+|calcium-binding-protein	unknown	unknown	gnl|CDD|380205
NC_008312.1|WP_011613149.1|5793962_5799539_+|WD-40-repeat-containing-protein	unknown	unknown	gnl|CDD|238121
NC_008312.1|WP_011613146.1|5789682_5790519_-|FtsQ-type-POTRA-domain-containing-protein	unknown	unknown	gnl|CDD|224505
NC_008312.1|WP_011613145.1|5788221_5789493_-|cell-division-protein-FtsZ	unknown	unknown	gnl|CDD|236468
NC_008312.1|WP_011613140.1|5772258_5773647_-|2-isopropylmalate-synthase	unknown	unknown	gnl|CDD|223197
NC_008312.1|WP_155994482.1|5771979_5772132_-|hypothetical-protein	unknown	unknown	gnl|CDD|377472
NC_008312.1|WP_044137774.1|5775406_5777062_-|hypothetical-protein	unknown	unknown	unknown
NC_008312.1|WP_011613136.1|5754716_5762189_-|methyltransferase-domain-containing-protein	unknown	unknown	gnl|CDD|226428
NC_008312.1|WP_011613141.1|5774036_5774372_-|SDR-family-NAD(P)-dependent-oxidoreductase	unknown	unknown	gnl|CDD|237218
NC_008312.1|WP_155994481.1|5766298_5766439_+|transposase	unknown	unknown	gnl|CDD|284650
NC_008312.1|WP_011613143.1|5784150_5784537_+|DNA-sulfur-modification-protein-DndE	unknown	unknown	gnl|CDD|378074
NC_008312.1|WP_011613144.1|5787327_5788164_-|bifunctional-hydroxymethylpyrimidine-kinase/phosphomethylpyrimidine-kinase	unknown	unknown	gnl|CDD|180561
NC_008312.1|WP_011610772.1|5782719_5783757_+|IS630-family-transposase	unknown	unknown	gnl|CDD|315923
NC_008312.1|WP_011613137.1|5762329_5764039_-|FkbM-family-methyltransferase	unknown	unknown	gnl|CDD|276809
NC_008312.1|WP_155994484.1|5785913_5786057_+|hypothetical-protein	unknown	unknown	unknown
NC_008312.1|WP_155994483.1|5781862_5781979_+|transposase	unknown	unknown	gnl|CDD|379129

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_008312.1|WP_011613143.1|5784150_5784537_+|DNA-sulfur-modification-protein-DndE	gnl|CDD|378074	pfam08870, DndE, DNA sulphur modification protein DndE. DndE is a small protein of 126 residues. It is a putative carboxylase homologous to NCAIR synthetase. It is encoded by an operon that is associated with a sulphur-based modification to DNA.	1.92777e-59
NC_008312.1|WP_011613138.1|5764285_5766127_+|ATP-dependent-metallopeptidase-FtsH/Yme1/Tma-family-protein	gnl|CDD|273520	TIGR01241, ATP-dependent_zinc_metalloprotease_FtsH, ATP-dependent metalloprotease FtsH. HflB(FtsH) is a pleiotropic protein required for correct cell division in bacteria. It has ATP-dependent zinc metalloprotease activity. It was formerly designated cell division protein FtsH. [Cellular processes, Cell division, Protein fate, Degradation of proteins, peptides, and glycopeptides].	0
NC_008312.1|WP_081432485.1|5773772_5774021_-|SDR-family-oxidoreductase	gnl|CDD|379263	pfam13561, adh_short_C2, Enoyl-(Acyl carrier protein) reductase.	1.9552e-15
NC_008312.1|WP_081432561.1|5770703_5771591_+|calcium-binding-protein	gnl|CDD|380205	NF033203, entero_EhxA, enterohemolysin EhxA. Members of this family are the RTX toxin called enterohemolysin or EhxA, because it is found in enterohemorrhagic Escherichia coli (EHEC) strains such as O157:H7.	1.00146e-12
NC_008312.1|WP_011613149.1|5793962_5799539_+|WD-40-repeat-containing-protein	gnl|CDD|238121	cd00200, WD40, WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from its N-terminus and the WD dipeptide at its C-terminus and is 40 residues long, hence the name WD40; between GH and WD lies a conserved core; serves as a stable propeller-like platform to which proteins can bind either stably or reversibly; forms a propeller-like structure with several blades where each blade is composed of a four-stranded anti-parallel b-sheet; instances with few detectable copies are hypothesized to form larger structures by dimerization; each WD40 sequence repeat forms the first three strands of one blade and the last strand in the next blade; the last C-terminal WD40 repeat completes the blade structure of the first WD40 repeat to create the closed ring propeller-structure; residues on the top and bottom surface of the propeller are proposed to coordinate interactions with other proteins and/or small ligands; 7 copies of the repeat are present in this alignment.	4.14871e-87
NC_008312.1|WP_011613146.1|5789682_5790519_-|FtsQ-type-POTRA-domain-containing-protein	gnl|CDD|224505	COG1589, FtsQ, Cell division septal protein [Cell envelope biogenesis, outer membrane].	5.56552e-24
NC_008312.1|WP_011613145.1|5788221_5789493_-|cell-division-protein-FtsZ	gnl|CDD|236468	PRK09330, PRK09330, cell division protein FtsZ; Validated.	0
NC_008312.1|WP_011613140.1|5772258_5773647_-|2-isopropylmalate-synthase	gnl|CDD|223197	COG0119, LeuA, Isopropylmalate/homocitrate/citramalate synthases [Amino acid transport and metabolism].	3.75562e-89
NC_008312.1|WP_155994482.1|5771979_5772132_-|hypothetical-protein	gnl|CDD|377472	pfam05145, AbrB, Transition state regulatory protein AbrB. Bacillus subtilis respond to a multitude of environmental stimuli by using transcription factors called transition state regulators (TSRs). They play an essential role in cell survival by regulating spore formation, competence, and biofilm development. AbrB is one of the most known TSRs, acting as a pleotropic regulator for over 60 different genes where it directly binds to their promoter or regulatory regions. Many other genes are indirectly controlled by AbrB since it is a regulator of other regulatory proteins, including ScoC, Abh, SinR and SigH. Hence, AbrB is considered a global regulatory protein controlling processes such as Bacillus subtilis growth and cell division as well as production of extracellular degradative enzymes, nitrogen utilization and amino acid metabolism, motility, synthesis of antibiotics and their resistant determinants, development of competence, transport systems, oxidative stress response, phosphate metabolism, cell surface components and sporulation. AbrB is a tetramer consisting of identical 94 residue monomers. Its DNA-binding function resides solely in the N-terminal domain (AbrBN) of 53 residues. Although it does not recognize a well-defined DNA base-pairing sequence, instead, it appears to target a very weak pseudo consensus nucleotide sequence, TGGNA-5bp-TGGNA, which allows it to be rather promiscuous in binding. The N-terminal domains of very similar sequences are present in two more Bacillus subtilis proteins, Abh and SpoVT. Mutagenesis studies suggest that the role of the C-terminal domain is in forming multimers.	0.00520395
NC_008312.1|WP_011613148.1|5792468_5793836_+|ATP-binding-protein	gnl|CDD|379062	pfam13191, AAA_16, AAA ATPase domain. This family of domains contain a P-loop motif that is characteristic of the AAA superfamily.	0.000241228
NC_008312.1|WP_011613136.1|5754716_5762189_-|methyltransferase-domain-containing-protein	gnl|CDD|226428	COG3914, Spy, Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones].	2.40795e-87
NC_008312.1|WP_011613141.1|5774036_5774372_-|SDR-family-NAD(P)-dependent-oxidoreductase	gnl|CDD|237218	PRK12825, fabG, 3-ketoacyl-(acyl-carrier-protein) reductase; Provisional.	8.60652e-31
NC_008312.1|WP_155994481.1|5766298_5766439_+|transposase	gnl|CDD|284650	pfam07282, OrfB_Zn_ribbon, Putative transposase DNA-binding domain. This putative domain is found at the C-terminus of a large number of transposase proteins. This domain contains four conserved cysteines suggestive of a zinc binding domain. Given the need for transposases to bind DNA as well as the large number of DNA-binding zinc fingers we hypothesize this domain is DNA-binding.	3.95497e-07
NC_008312.1|WP_011613144.1|5787327_5788164_-|bifunctional-hydroxymethylpyrimidine-kinase/phosphomethylpyrimidine-kinase	gnl|CDD|180561	PRK06427, PRK06427, bifunctional hydroxy-methylpyrimidine kinase/ hydroxy-phosphomethylpyrimidine kinase; Reviewed.	5.84894e-147
NC_008312.1|WP_011610772.1|5782719_5783757_+|IS630-family-transposase	gnl|CDD|315923	pfam13358, DDE_3, DDE superfamily endonuclease. This family of proteins are related to pfam00665 and are probably endonucleases of the DDE superfamily. Transposase proteins are necessary for efficient DNA transposition. This domain is a member of the DDE superfamily, which contain three carboxylate residues that are believed to be responsible for coordinating metal ions needed for catalysis. The catalytic activity of this enzyme involves DNA cleavage at a specific site followed by a strand transfer reaction.	9.9949e-34
NC_008312.1|WP_011613137.1|5762329_5764039_-|FkbM-family-methyltransferase	gnl|CDD|276809	sd00006, TPR, Tetratricopeptide repeat. The Tetratricopeptide repeat (TPR) typically contains 34 amino acids and is found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi, plants, and humans. It is present in a variety of proteins including those involved in chaperone, cell-cycle, transcription, and protein transport complexes. The number of TPR motifs varies among proteins. Those containing 5-6 tandem repeats generate a right-handed helical structure with an amphipathic channel that is thought to accommodate an alpha-helix of a target protein. It has been proposed that TPR proteins preferentially interact with WD-40 repeat proteins, but in many instances several TPR-proteins seem to aggregate to multi-protein complexes.	1.66905e-19
NC_008312.1|WP_155994483.1|5781862_5781979_+|transposase	gnl|CDD|379129	pfam13340, DUF4096, Putative transposase of IS4/5 family (DUF4096).	2.20165e-06

Protein sequences

>NC_008312.1|WP_011613141.1|5774036_5774372_-|SDR-family-NAD(P)-dependent-oxidoreductase
MAGVNNPDTVQKMVDFAIEKFGAVDIAVSNISLEKRQNFLDISLKDWHEVIKTNLNSAFYLAKAIIPGMKARRWGRIIYISGYYGSIGTLYQAHNVTCKGGLNAFAKAIAT
>NC_008312.1|WP_081432485.1|5773772_5774021_-|SDR-family-oxidoreductase
MTAKRVSPGTIDTIRISKDYPNLDTKYEIMEKMIPVGRLASCQDIVETCLYIASDCSGFVNGQVINVNGGGLIITAHLDPII
>NC_008312.1|WP_011613140.1|5772258_5773647_-|2-isopropylmalate-synthase
MVQIVDSTLREGRQTAPGINFSWEQSLKIAKLLHSLGIDIIEVCHPVVSIEQKQIVREIVASNLCPVIAHARANLADIEAVKETSAQWVGIFLGINEETRLTRARWTISKIFNCIKESVMYAKTLGLKVRYTAEDASRTDYCLLKSVYSVAIEAGADCICFSDTVGIMEPNEVTETIEKLKSDFSTVPLEVHFHNDRGLAMANALAASDAGAERISSSVNGLGERCGITDTLGLLVNLYYKGLRSLPSGEIIQRTSKYVAAFSRYPVNFNQPISGGNAFIHTAHLHQKAVKRDPSSYSWILPEYVGKTMELSGKSIPSVHSLFLTPIVKCASELGYHRYGDSVGHLMIDECMVPNCRQSCIVREIRVVEEKPLAYVDVQTLYVDSLFLFLGHELGMKGLQVEVCLGQVVQKIDSPASVFIPAGVAHTYRILNGSGFCINHVLSGSYNDSLLEPLDISSNSYS
>NC_008312.1|WP_155994482.1|5771979_5772132_-|hypothetical-protein
MIATVNELGGDAGLVLGIQLTRMLILLFVAPLLRNFIVKKEKPIDIVSEQ
>NC_008312.1|WP_081432561.1|5770703_5771591_+|calcium-binding-protein
MYFNGSVNTNTSVELVPLDIELELYDPIRRTESFEFDFDIVATTNTSNPQESADFVFPLNKVTDSSFKYKGKDYTIRILGFSQDKGRTFTREFRVLEDARTTAGLYAKIELDKGIGTSRADKLTGSNRDERLDGRGGNDQLIGRGGDDILIGGSGKDRLNGGSGNDKLNGGAGNDTLTGAAGVDTFVYDTGRNFRRRDIGVDKIVDFMLDEDTIVLSRTTFSKIESLAGSILQEFEVVDSNNAAIKSNAFIVYNQSNGNLYYNQNGSNNGFGSGGLFARLEGRPALEATDFFIDN
>NC_008312.1|WP_044136906.1|5770498_5770714_+|hypothetical-protein
MALKFAGFFNSKWGEPIPGKDNQAPVFVGVDTHSFKWGSPANSRTYPNELSFVIDPFSTQLKVQSRRFNLL
>NC_008312.1|WP_155994481.1|5766298_5766439_+|transposase
MQGAAFSQFLQILEYVAWKLGKKIIKVDPIGTSQNCWEYLNKVSKS
>NC_008312.1|WP_011613138.1|5764285_5766127_+|ATP-dependent-metallopeptidase-FtsH/Yme1/Tma-family-protein
MNNKKWRNAGLYALLAIVVIALATAFFDQQPQARETWKYSQFIQQVENKNVEKVDISADRTVARVKVADGSVVRVNLPNDPDLINILTQNNIDISVLPQNEEGFWVRALSSLFFPILLLVGLFFLLRRAQSGPGSQAMNFGKSKARVQMEPQTQVTFSDVAGIEQAKLELTEVVDFLKNADRFTAIGAKIPKGVLLVGPPGTGKTLLAKAVAGEAGVPFFSISGSEFVEMFVGVGASRVRDLFEQAKSSAPCIVFIDEIDAVGRQRGAGLGGGNDEREQTLNQLLTEMDGFEGNTGIIIIAATNRPDVLDAALLRPGRFDRQVVVDRPDYAGRLEILNVHARGKSLSKDVDLEKIARRTPGFTGADLSNLLNEGAILAARRNLTEISMDEVNDSIDRVLAGPEKKDRVMSEKRKELVAYHEAGHALVGALMPDYDPVQKISIIPRGRAGGLTWFTPSEDRMDSGLYSRAYLQNQMAVALGGRLAEEIVFGDEEVTTGASNDLQQVARVARQMVTRFGMSDRLGPVALGRQNGNMFLGRDIMSERDFSEETAAAIDDEVSNLVDQAYRRAKEVLVGNRHILDRLAEMLVDKETVDSDELQELLATNDVKMAALI
>NC_008312.1|WP_011613137.1|5762329_5764039_-|FkbM-family-methyltransferase
MTNLNYLETSGWLKSLKEGKSIDYNSNPLPWYSYPAIEFIEDKLKSDFRVFEYGSGQSTLWYAQRVKEVISVEHNPDYFCQIKSYTPENVILSLLEDQEKYAAEINRYNDSYFDIIVIDGINRGRCAELCYRKLTANGLIIFDNSDREESDASLEFLQERKFKRLDFYGLLPTQKYKICTSIFWQDEELFNRASLPSKKNSCLGISLGQVEAINKRKNKNKASQDNQILACYEAIKNQPYFAEAYQRLGDMCYSQGQIEKSIRSYKKAIELQPDLAVVYAKLGKIYYQKSQLQEAIAYYQKVITLEPKSADIYWGISQILQQQGRLSEANIYRQKALETERDLTVKSFALNQLDLKLAPYLTWENGFFIEAGANDGISQSNTLYFEKYKNWQGILIEAIPELAEKCRVNRSKSVVENYALVPFDYGQDYIKLYYCNLMSFVDGAMKSEEEKKVHLKAGCQVQNINHSYEINVPATTLTAIIDKYGVENIDLFSLDVEGFELGVLQGIDFDKYQPKFMLIEVRLRDRKTIDSFLKPLYEPIAVLSDSINQTLPERSYQDILYKATNIKSR
>NC_008312.1|WP_011613136.1|5754716_5762189_-|methyltransferase-domain-containing-protein
MTQFQLTTPVVIIIFNRPDTTEKVFQRIRQVKPPQLLVIADAPRPDKPGEVEKCIAARKIVDLVDWKCEVLTNYAEVNLGCRERIYSGLNWAFSLVESAIILEDDCVPHLTFFRFCQELLDIYQDNNKVMAISGDNFQFGNNSIEYSYYFSRYPHCWGWATWRRAWKNYDNQMQLWPKLRDSKWLENILQNSHAVQYWSKIFQNNYQGFNSWAYAWIFASWNHHSLIILPKVNLVSNIGFGEEATHTLSINKFANMSTEEMIFPLNHPPSIIRNIEADEFTEKTMFSGSLQLQNVHCKVCGSISCKFDDAKVLNKYNVEYFQCSNCGFVQTENPYWLAEAYKEAIASSDVGLVSRNQNFSLITENLILNLFNTNSKFLDYGCGYGLFVRMMRDLGLDFYGYDKYCQNIFYQGWEGEINKQQKYEIITAFEVFEHFINPLAEIENILQHTRNILFSTKLLPPNNPHPNDWWYYALEEGQHISIYTTKALSVIGQKFKLNLYSDGESLHLLTEKSLSHSEFQNIFKVARYKPENRKKTLTQLDHEKVTEKKKKNQQQLDLKLLIDGVFFQINNTGIARVWKSLLEVWSKDSFAKNILVLDRAKTAPKIPGINYRSVPGYNYGKIDADRQMLQTICDEENADIFISTYYTTPILTPSVFMAYDMIPEVLAKNLNNPSWQEKHRSIRQAISYVAISENTARDLIKYFPQIPANYIRVAPCGIEAKFSRTTPQEVASFKSKYHINKPYFLIVGERIGWLGYKNTILFFQAFSKLKKSTEFDIVCIGGNRKLEPELSKYISGSKIHLLQLSDQELKSAYSAAIALVYPSKYEGFGLPILEAMACGCPVITCKNSSIPEVAGTAALYINDNDINSLVNALGEVQKSEVQQKLITAGLAQAQKFSWSQMAKIMSDVFIQTFNQIKAKRLSTMEDRKNLGEIQFKINHGQLEMQRHFWNVNSLDEAMFGRVLAYNGMDTLSPEEKKQAWEKSIENWVPQIMEGIPTKPEWKVLEIGCGVGRLIKYLRAKFARVDGVDISENMIQFARQYLADGKQNGEVYVNNGYDLQQLPDENYDFVFSTIVFQHIRSISIVKNYFREIFRVLKMGGYFRIQVHDYSAESLGKFDEEGAKDQQYYFSGNAYTEEQLKDLLIAAGFNLVSLKSAKPWIWATARREQQVEVGVEKIPQIVTLKNNQMGIEYPEINRLSYNKDRPFWSVMIPTYKKVKYLEQTLKSVLQQAPPPEEMQIEVVNDCPDYKIQAEIEAIVRKVGGERINCYRHFPQDIGQAPIFNICLQRAKGYWVHLLHDDDFVLPGFYEKLRRGIEKNTTLGAAFCRHYYIDENDHKKYLSVLERDTPGVIEKFIEKITVEQRIQVVGMVVKREVYEHLGGFCSQAASAADWEIWKRIAAFYPIWFEPEILACFRLHSSSETSRLMQSGGNIENARKAIEITQTYLPRNMAAELSNQAREHYGIEAMKMAASMLKIGNNNGAIAQMREGLKCSNSSSVINLLVSILINAETEAETSLIQATSQHLLSLEPQLIESKKTPHKVETNLLPSLAEINKEIELYKQNQLDKSALVKLQEIRKKIAYFWLSIDTLENLKIAYLGDFCQIHKALLTSSITDESLTETEKKIVTQIKANIVKGFKEPLDIKYLLAGMLYQRADQLEVKYEKAPIPKWFAIDYLNFMFASPQVFQEIGETDNYYHFMTGWLSYVHNNISINSESELWQAIARIFVENANWIPLYFTTRPNLKNLYIKRAEIIEFALKKLGLELNYTMPPYQFNRSKIRLGIIKDHYTPQTETYSLLPVFEHLDRSKFEIFLYAIKSNGHPLEQYCQSRADKFLQLPNELKNQVQTIRDDNLDILFFGSNITATIKNSTLLATHRLARVQVTSINSPTTTGMASIDYYISGKLTAPTEMTKEHYTEKLVNLEGSGLCFQDPIAETLPVVQPLRSSWGATNETTIFISGANFYKIIPEIRETWAKILRAVPNSILVLYPFNPNWTNSYPVGSFIQQMRGTLERHGIHSKRLVVIKPLPSKSDIKKCLELADIYLDSFPYGGATSLLDPLMLGLPPVVVEGNALRFRQGPALLREINIEDLIADGEESYINLAVKLATNSEWRQQKRQEIKEKMQQNPAFLDSRSYSAEIGKLFQELFQKWQNIHAPKTIESQDNNSLTSEFINRLVGCVNLYKIDPNDQSLIEELRQIRKQIANFWLDTNPQKLEIIYQGKVRQAYLSLLSSGIQNEPQTEKEEKFIKELTDISMGLTNSKSINALLGGMLYFLPGKMLVRDAKNRLPEWLINDYQQVFESREVVQKLEKDFQTKLPHFSEDSISRDLVSKPIKIAEVQTEKNIFLTENKADNLDFVISKFLNQLLGNVNLYYIDPSDESVVKELRQLRKQMADFWINLEPQKLENFYLGEMGKAYQALLNSEIQNQSLIESEQEFLQQLATQLSQGIEAPKAINYLLAAILYCRPEQLRIEDATKLPQWLLSDYQKFIGN
>NC_008312.1|WP_044137774.1|5775406_5777062_-|hypothetical-protein
MTFAVIYGFLAVKKAFISSLSVQDDARQHIFWMQRFFDPDLFPNDLIADYFQSVAPAGYTWLYKSAAFVGINPLILAKIIPFILGLICTYYIFRITLEILPVPMAGFIATLVMNQAIWMKDDVASATPRAFVYPFFMAFLYYLICGSLVRMGIAIALVGLFYPQYVFVASGMLILRLICWRNGRFQFSSKKQDFIFCGVGLSMAFFILLPYALTSSEFGPAISREAAMKLREFYPNGRSTFFHVHPKDFWLTGKRSGMFPKSLFTPATQCAGLVLPFLLSFGSAFPLIKNITSRIWLLLHLLLSSLGMFFIAHVLLFRLHLPSRYTGLSFRIIIALATAIALTLIIDALFNWAKNIHKFPVAFRGIISLSLIGLILASLVLYPSFVKGFPLVKYKVGRATYLYDFFQEQPKDILIASLEEEANLLPTFAQRSILLGREYAIPYQVGYYSQFRERTIDLIVAQYSSDLTDVKDFIQKYGIDFWMVHRGAFTPEYVEDNSWLMQYKFAQEAVTFLQLGNIPALATTISNCVVFQSDSLFVLDANCILRKGVGE
>NC_008312.1|WP_155994483.1|5781862_5781979_+|transposase
MLINSIFYILYSSFHWRSLPQKLQPWQTVSTKFRKCHG
>NC_008312.1|WP_011610772.1|5782719_5783757_+|IS630-family-transposase
MNIIDKLNDFINQTKESKEIKRALAVKMTLSGKSYHEVKELLNVSHSFISEWKNQALFHGVESLRLQYQGRQGYLKTVEKEKTIEWLRAQDYLRLSDLKNYLQEQYDVVFESNQSYYNLFKEAGISWKKTQKKNPAKNDELVEVKRKEIQEFLAKWQPEIETGKLTVFMIDECHLLWGDILGYAWGKTDERIEIAIKNEKERQTYYGALDYKTKEFLVQEYESGNTKNTIEFIKYLQKQRPGNKLAIFWDGATYHNSQEFREYLMTINQYLSEEELLINCTRFAPNAPEQNPVEDIWLQTKNFSITFYHLCSSFKVVKWLFKFFADGQIFNFPKLFQYEILPQPT
>NC_008312.1|WP_011613143.1|5784150_5784537_+|DNA-sulfur-modification-protein-DndE
MEPPIERIRLSQVAKEQLTKLKRNTKIDQWNILCRWAFCCSLAELSIPSPVPIPADSNLELTWRIFGGKFADILLVALKQRCHNDGIGIDQETLASQFRLHLHRGIGYLAGDPNIKNIEKLIVTVLDS
>NC_008312.1|WP_155994484.1|5785913_5786057_+|hypothetical-protein
MANKSIGVVYNWLHHLIPDSPWEPTKINQPRLERMNKPSQTKSFFVE
>NC_008312.1|WP_011613144.1|5787327_5788164_-|bifunctional-hydroxymethylpyrimidine-kinase/phosphomethylpyrimidine-kinase
MADFMASSIPVALTIAGSDSGGGAGIQADLRTFAFHCVHGTSALTCITAQNTLGVNRLDALLPEVVKAQIEAVVQDIGVQATKTGMLLNQDIILVVAEVLETLSLKQLVVDPVMVSRAGVQLIDNSAVAALRDFLLPKASIVTPNIYEAQILAGLDINNINDMKLAAEKIHKFGVNTVLVKGGALKHNLRGVDVWFDGESFETLKTSTVDTNNTHGTGCTLSAAIAANLAQGQDLFSAVTMAKNYVTSSLQYALEIGQGQGPIGHFFPLLLNNYIKSS
>NC_008312.1|WP_011613145.1|5788221_5789493_-|cell-division-protein-FtsZ
MIVNNKQGVKYYESPQYQGQGNFPLPNNVSNPFRNSSGFYGEQNYDPKGIIKEESRSDDIVPSNTAKIKVIGVGGGGGNAVNRMIASEVSGIEFWTVNTDAQALTLSRAPKRLQLGQKLTRGLGAGGNPAIGQKAAEESRDEIANALDHPDLVFITAGMGGGTGTGAAPVIAEIAKEAGSLTVGVVTRPFTFEGRRRITQADEGITALQTRVDTLIVIPNNRLLSVINDQTPVQEAFIIADDILRQGIQGISDIITVPGLVNVDFADVRAVMADAGSALMGIGMGSGKSRAREAANAAISSPLLESSIEGAKGVVFNITGGTDLTLHEVNAAAEIIYEVVDPNANIIFGAVIDDKLQGEIKITVIATGFSGEVQTQPIQEKVQPRRPVPNPTQNPNSTPEPQRKLPGLDIPDFLQRRRNPSNK
>NC_008312.1|WP_011613146.1|5789682_5790519_-|FtsQ-type-POTRA-domain-containing-protein
MANNIGSVSESDLVSRRQKLRLQRRLKLLVIVWQVLAVGGLGAALLWAITQPIWLITKQEQLTVEGNQLLSDRAILSLISLDYPQSLWVIKTQILAQNLESQSPIAKARISRRLFPPSLNIKIIERRPVAITQFKNQVGINNSQKMGWLDTHGNWIPLESFSALERTGSLPTLKVIGFTGQYRQYWHSLYQSLSRSPVKVFEINWQDPGNLILTTELGIVHLGPYSSRFSEQLNVLDRMRELPNKIDVRQMAYINLKNPDSPLIQLPNKFKAIKIQSN
>NC_008312.1|WP_011613148.1|5792468_5793836_+|ATP-binding-protein
MEVKKLLSKLDLIRFYKACNPSKTLIVGNAEDQQYYIDFASVRGSDIIKELERTIILLSGNQPTCQLFTGHIGCGKSTELFRLKDKLEKQGYHVVYFESSEDLDMGDVDISDILLAIARQVSESMEQAKIQIKPSYFQKLFGEISELLQTPIELSAEAELSVGIAKITAKTKDSPKLRSQLRQYLEPRTSTILESINQELLERTNIELKRRDKKGLVVIVDNLDRVDNSPKSWGRTQPEYLFVDRGEQLKKLNCHVVYTIPLTLMFSNDYGRLSSRFGVKPKILPMVPVQIRSKKPTIAPNDYETGIKLLREMVLARAFPEIPSQKRLEFIPALFETSETLDRLCRVSGGHMRKLLMLLYSCLQQEDPPFSSECLENVIQEYRDDLTRAITVDEWELLFKVVQNQRVTGEEECQALLRSMFVFEYRDRDGHWFGINPLLAETKKYASWVNSNYQE
>NC_008312.1|WP_011613149.1|5793962_5799539_+|WD-40-repeat-containing-protein
MEPLKYPEESIIYNKRSLTRLMRSVTISQGQFSLILACCNYQHFQQRMMMEVKKMLSVELQEIVLSKTVTTLYTTIDQQLEKFPEAPAVMILNLDKVEAIDELLISTNQVRDEFRKKFSFPLILWITDKLLAKLIRLAPDFKSWAAATIKFEFATSDLIHLLKMAIDSYWINESANEQQQLIKSSSNSTKYNFLVPSFLDQSNCYYGKKLSQNKHQEIQLAFKDLKEREQHLETTLKAKIEFIIGRDYFYNNNIDSALEHYQESLNLWEYKIGSLEYPKSSIISERFILEQKGIVLYNIALCYYLQSTQNPLDNYQELEKAKLKLEESKQLFEEVNNFVLVAEVITTLGQAIKQMKAWGELEAIALEGLQLHHKYGNDLQIAQDYGFLAEVALQKSNWVEAQKLSERALNILFYAKDITLPTEKNKYLLLLAKSLKNLYRQAEAIEYLEIAELTEQEAIKNSLKTQENRDPKLYIELLTELGSLYYNQGKYLQAFRLKKAQRKIAHQYGLLAFIGASQLQPQKQSYIKESLDYQNTLPSEITASGRQKDINNLLERISRNDCKLTIIHGRSGVGKSSLVNAGLIPALKNISISARDTVLVAVQRYNDWLEVLAYSLNKSLQKKCKLRNNNNLFKLKKDYIKNQESIFSIRGKNLNSEVEKTYDSELKDEFQCIESCVIAQLKNNSENNLLTVIVFDQFEEFFFFNNSSEDREVFYRFICNCLNLPFVKVILSMREDYLHYLLEWDFISDLDVINNNILDKDIRYHLRDFSREDAYTVIECLTKRAKFNLEPQLIDVIVDGLADEKQQIRPIELQVVGSQLQEEKPQIQTLDQFQKKFDINPKKAKAKLIKNFLEQVIIDCGQENEEATMQVLFALTNDNLTRATRTKKELLEIVKTCIETSFLVNVDSSKFVENQINYNEKIEGLLNLILEILVDSGLLFIRQECNEKNYQLVHDYLVKPIRKRFDLENRLQQAEVEIKNAEIAKNKAETDKITSQAKLNILLKRQLAVAILGIILMSMSTIATLGFWQKTRFQKQVATAQKERADINSMTAFSEALFFSGYKFDALIESIKAGKKWQKIKQLLGEQNLSNDTEYRIAASLQQAVYGVNKYNHLEGHNNIVWSVIFHPEGNLIASASADKTIKLWSRDGKLQKTLTNHKNRVSKISFSSDGKYLASASHDSTVKIWDLQQLEMKPLSLKSHSDSVVTINFSPNNKMLASGSLDKTIKIWNYTGVLLRTIRTKSVVKWVSFSPNGKMIAAANANGTVQLWNLNGKLLKTLKHGAGNHNYPVYSANFSPDGKRMVTASGDQTVKIWRFFRNIPILEKTITGHKKQVINASFSPDGKIIASSSTDKTIKVWQLDGTLLKTFSGHGDTVTQVTFSPDGETLASASYDKTIKFWSLKNDSLNVLQGHKHRVLGVSFSPDGQILASASQDNTIKLWSPTGKLLNNLEGHTDRVASVSFSSDAQILASGSYDNTVKLWYLNSPNQIWNWKFLEDPKSWQLLGKNHQLFTLKNEKNKLYLVEQVKFLENFLSTNLNCFLNARSFCLVPWGKITSFFPRNFSLLPRQFLEELKYQSWFEIAADNQVKVQCRLLQCLQNEIITVGVDWNWNTDDYLIDFTSKSINLIGHTDSLLSVSFSPNNQVIASSGKDKTIRLWNREGKLLKTLVGHNEWVSSVSFSPDGKILASASDDGTVKLWTQKGVLLKTINAHSGWVLGVSFSPNGQAIATASYDNTVKLWSLDGELLRTFLKGASDSVTSVSFSPDGQAIASSSYDGKVKLWSLYDGSLLKTLNGHQDSVMSVSFSPDGKLLASGSRDKTVILWDLALDSLLDQGCSWVRDYLRTNPHVSQSDRQLCEK

Crispr_ID: NC_008312_40

• CRISPR_ID: NC_008312_40
• CRISPR_location: 5910066-5910395
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 3 spacers

Consensus repeat of NC_008312_40

Consensus_repeat	Method
CTCAGGAAATGGAGGAGCAATTAATTTGGATGCTGGTGGCAATATCACTACACAATCCCTCAAT	PILER-CR

spacers of NC_008312_40

>40.1|5910130|23|NC_008312|PILER-CR
TCCAGGTCCACTGCCAGATCATT
>40.2|5910217|35|NC_008312|PILER-CR
GAACTCTATTCCTATTCCTATTCCAGCTTAGACAA
>40.3|5910316|26|NC_008312|PILER-CR
GCATATTCTTTTTCCCCCTCAGGCAA

CRISPR arrays and Neighbor proteins around NC_008312_40

CRISPR arrays

The CRISPR arrays of NC_008312_40

>merge|NC_008312|40|5910066-5910395|PILER-CR
TCAGGAAATGGAGGAGCAATTAATTTGGATGCTGGTGGCAATATTACTATACAATCCCTCCATTCCAGGTCCACTGCCAGATCATTCTCAGGAAATGGAGGAGCAATTGATTTGGATGCTGGTGGCAATATCACTACACAAGAACTCTATTCCTATTCCTATTCCAGCTTAGACAACTCAGGAAATGGAGGAGCAATTAGTTTGGATGCTGGTGGCAATATCACTACACCATCTCTCAATGCATATTCTTTTTCCCCCTCAGGCAACTCAGGAAATGGAGGAGCAATTAGTTTGGATGCTGGTGGCAATATCACTACACAATCCCTCAAT

>NC_008312|40|3|5910066-5910395|PILER-CR
TCAGGAAATGGAGGAGCAATTAATTTGGATGCTGGTGGCAATATTACTATACAATCCCTCCATT	CCAGGTCCACTGCCAGATCATTC
TCAGGAAATGGAGGAGCAATTGATTTGGATGCTGGTGGCAATATCACTACACAAGAACTCTATT	CCTATTCCTATTCCAGCTTAGACAACTCAGGAAAT
GGAGGAGCAATTAGTTTGGATGCTGGTGGCAATATCACTACACCATCTCTCAATGCATATTCTT	TTTCCCCCTCAGGCAACTCAGGAAAT
GGAGGAGCAATTAGTTTGGATGCTGGTGGCAATATCACTACACAATCCCTCAAT

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_008312.1|WP_044136915.1|5925253_5925670_+|hypothetical-protein	unknown	unknown	gnl|CDD|367137
NC_008312.1|WP_011613195.1|5881442_5887172_+|type-I-polyketide-synthase	unknown	unknown	gnl|CDD|225858
NC_008312.1|WP_011613206.1|5919176_5920268_-|class-I-SAM-dependent-methyltransferase	unknown	unknown	gnl|CDD|225136
NC_008312.1|WP_011613201.1|5900217_5901993_-|AarF/ABC1/UbiB-kinase-family-protein	unknown	unknown	gnl|CDD|223733
NC_008312.1|WP_011613204.1|5917265_5918024_-|lipoate--protein-ligase-family-protein	unknown	unknown	gnl|CDD|319742
NC_008312.1|WP_011613197.1|5891767_5892256_+|lipocalin-like-domain-containing-protein	unknown	unknown	gnl|CDD|372819
NC_008312.1|WP_011613212.1|5931919_5933398_-|DUF697-domain-containing-protein	unknown	unknown	gnl|CDD|368297
NC_008312.1|WP_011613202.1|5904038_5905364_-|hypothetical-protein	unknown	unknown	unknown
NC_008312.1|WP_044136913.1|5899521_5899725_+|hypothetical-protein	unknown	unknown	unknown
NC_008312.1|WP_011613209.1|5923743_5924598_+|TlyA-family-RNA-methyltransferase	unknown	unknown	gnl|CDD|224110
NC_008312.1|WP_011613199.1|5894130_5895816_+|hypothetical-protein	unknown	unknown	gnl|CDD|366799
NC_008312.1|WP_011613205.1|5918585_5919080_-|YbjN-domain-containing-protein	unknown	unknown	gnl|CDD|341119
NC_008312.1|WP_011613211.1|5927247_5928693_-|DUF697-domain-containing-protein	unknown	unknown	gnl|CDD|206646
NC_008312.1|WP_011613207.1|5920769_5922191_-|type-I-glutamate--ammonia-ligase	unknown	unknown	gnl|CDD|273198
NC_008312.1|WP_011613198.1|5892399_5893881_+|NAD(P)/FAD-dependent-oxidoreductase	unknown	unknown	gnl|CDD|224983
NC_008312.1|WP_011613196.1|5887336_5891401_+|type-I-polyketide-synthase	unknown	unknown	gnl|CDD|225858
NC_008312.1|WP_011613210.1|5926432_5927119_+|hypothetical-protein	unknown	unknown	unknown
NC_008312.1|WP_155994488.1|5897085_5899005_+|NAD(P)-binding-protein	unknown	unknown	gnl|CDD|109787
NC_008312.1|WP_011613194.1|5876967_5881329_+|AMP-binding-protein	unknown	unknown	gnl|CDD|341249
NC_008312.1|WP_011613208.1|5922959_5923469_+|allophycocyanin-subunit-beta	unknown	unknown	gnl|CDD|271281

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_008312.1|WP_044136915.1|5925253_5925670_+|hypothetical-protein	gnl|CDD|367137	pfam02668, TauD, Taurine catabolism dioxygenase TauD, TfdA family. This family consists of taurine catabolism dioxygenases of the TauD, TfdA family. TauD from E. coli is a alpha-ketoglutarate-dependent taurine dioxygenase. This enzyme catalyzes the oxygenolytic release of sulfite from taurine. TfdA from Burkholderia sp. is a 2,4-dichlorophenoxyacetic acid/alpha-ketoglutarate dioxygenase. TfdA from Alcaligenes eutrophus JMP134 is a 2,4-dichlorophenoxyacetate monooxygenase. Also included are gamma-Butyrobetaine hydroxylase enzymes EC:1.14.11.1.	6.9199e-14
NC_008312.1|WP_011613195.1|5881442_5887172_+|type-I-polyketide-synthase	gnl|CDD|225858	COG3321, COG3321, Polyketide synthase modules and related proteins [Secondary metabolites biosynthesis, transport, and catabolism].	0
NC_008312.1|WP_011613212.1|5931919_5933398_-|DUF697-domain-containing-protein	gnl|CDD|368297	pfam05128, DUF697, Domain of unknown function (DUF697). Family of bacterial hypothetical proteins that is sometimes associated with GTPase domains.	2.86749e-42
NC_008312.1|WP_011613201.1|5900217_5901993_-|AarF/ABC1/UbiB-kinase-family-protein	gnl|CDD|223733	COG0661, AarF, Predicted unusual protein kinase [General function prediction only].	2.05634e-90
NC_008312.1|WP_011613204.1|5917265_5918024_-|lipoate--protein-ligase-family-protein	gnl|CDD|319742	cd16443, LplA, lipoate-protein ligase. Lipoate-protein ligase A (LplA) catalyzes the formation of an amide linkage between free lipoic acid and a specific lysine residue of the lipoyl domain in lipoate dependent enzymes, similar to the biotinylation reaction mediated by biotinyl protein ligase (BPL). The two step reaction includes activation of exogenously supplied lipoic acid at the expense of ATP to lipoyl-AMP and then transfer to the epsilon-amino group of a specific lysine residue of the lipoyl domain of the target protein.	4.08449e-50
NC_008312.1|WP_011613197.1|5891767_5892256_+|lipocalin-like-domain-containing-protein	gnl|CDD|372819	pfam13924, Lipocalin_5, Lipocalin-like domain. This family includes domains distantly related to lipocalins. However, they do contain the important GXW motif in the first strand. The protein in this family include aln5, which is involved in biosynthesis of alnumycin. The family also includes the ZFK protein from Trypanosoma brucei which is a protein kinase. This domain is at the C-terminus of that protein. The domain is also found as the C-terminal domain in StiJ a protein involved in producing stigmatellin. This domain has been assumed to catalyze a final cyclisation reaction.	8.70929e-44
NC_008312.1|WP_011613206.1|5919176_5920268_-|class-I-SAM-dependent-methyltransferase	gnl|CDD|225136	COG2226, UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis [Coenzyme metabolism].	1.35873e-25
NC_008312.1|WP_011613205.1|5918585_5919080_-|YbjN-domain-containing-protein	gnl|CDD|341119	cd17036, T3SC_YbjN-like_1, T110839 is structurally similar to type III secretion system chaperones and YbjN family proteins. This family includes protein T110839 from Synechococcus elongatus that is structurally similar to type III secretion system (T3SS) chaperones (T3SC) that bind effector proteins, and is homologous to YbjN, a putative sensory transduction regulator protein found in Proteobacteria.	1.96999e-41
NC_008312.1|WP_011613209.1|5923743_5924598_+|TlyA-family-RNA-methyltransferase	gnl|CDD|224110	COG1189, COG1189, Predicted rRNA methylase [Translation, ribosomal structure and biogenesis].	1.41084e-117
NC_008312.1|WP_011613199.1|5894130_5895816_+|hypothetical-protein	gnl|CDD|366799	pfam01764, Lipase_3, Lipase (class 3).	0.00150056
NC_008312.1|WP_011613211.1|5927247_5928693_-|DUF697-domain-containing-protein	gnl|CDD|206646	cd00880, Era_like, E. coli Ras-like protein (Era)-like GTPase. The Era (E. coli Ras-like protein)-like family includes several distinct subfamilies (TrmE/ThdF, FeoB, YihA (EngB), Era, and EngA/YfgK) that generally show sequence conservation in the region between the Walker A and B motifs (G1 and G3 box motifs), to the exclusion of other GTPases. TrmE is ubiquitous in bacteria and is a widespread mitochondrial protein in eukaryotes, but is absent from archaea. The yeast member of TrmE family, MSS1, is involved in mitochondrial translation; bacterial members are often present in translation-related operons. FeoB represents an unusual adaptation of GTPases for high-affinity iron (II) transport. YihA (EngB) family of GTPases is typified by the E. coli YihA, which is an essential protein involved in cell division control. Era is characterized by a distinct derivative of the KH domain (the pseudo-KH domain) which is located C-terminal to the GTPase domain. EngA and its orthologs are composed of two GTPase domains and, since the sequences of the two domains are more similar to each other than to other GTPases, it is likely that an ancient gene duplication, rather than a fusion of evolutionarily distinct GTPases, gave rise to this family.	3.34658e-43
NC_008312.1|WP_011613207.1|5920769_5922191_-|type-I-glutamate--ammonia-ligase	gnl|CDD|273198	TIGR00653, Glutamine_synthetase, glutamine synthetase, type I. Alternate name: glutamate--ammonia ligase. This model represents the dodecameric form, which can be subdivided into 1-alpha and 1-beta forms. The phylogeny of the 1-alpha and 1-beta forms appears polyphyletic. E. coli, Synechocystis PCC6803, Aquifex aeolicus, and the crenarcheon Sulfolobus acidocaldarius have form 1-beta, while Bacillus subtilis, Thermotoga maritima, and various euryarchaea has form 1-alpha. The 1-beta dodecamer from the crenarcheon Sulfolobus acidocaldarius differs from that in E. coli in that it is not regulated by adenylylation. [Amino acid biosynthesis, Glutamate family].	0
NC_008312.1|WP_011613198.1|5892399_5893881_+|NAD(P)/FAD-dependent-oxidoreductase	gnl|CDD|224983	COG2072, TrkA, Predicted flavoprotein involved in K+ transport [Inorganic ion transport and metabolism].	1.22316e-106
NC_008312.1|WP_011613196.1|5887336_5891401_+|type-I-polyketide-synthase	gnl|CDD|225858	COG3321, COG3321, Polyketide synthase modules and related proteins [Secondary metabolites biosynthesis, transport, and catabolism].	0
NC_008312.1|WP_155994488.1|5897085_5899005_+|NAD(P)-binding-protein	gnl|CDD|109787	pfam00743, FMO-like, Flavin-binding monooxygenase-like. This family includes FMO proteins, cyclohexanone mono-oxygenase and a number of different mono-oxygenases.	3.06259e-55
NC_008312.1|WP_011613194.1|5876967_5881329_+|AMP-binding-protein	gnl|CDD|341249	cd05926, FACL_fum10p_like, Subfamily of fatty acid CoA ligase (FACL) similar to Fum10p of Gibberella moniliformis. FACL catalyzes the formation of fatty acyl-CoA in a two-step reaction: the formation of a fatty acyl-AMP molecule as an intermediate, followed by the formation of a fatty acyl-CoA. This is a required step before free fatty acids can participate in most catabolic and anabolic reactions. Fum10p is a fatty acid CoA ligase involved in the synthesis of fumonisin, a polyketide mycotoxin, in Gibberella moniliformis.	1.98402e-140
NC_008312.1|WP_011613208.1|5922959_5923469_+|allophycocyanin-subunit-beta	gnl|CDD|271281	cd12126, APC_beta, Allophycocyanin beta subunit of the phycobilisome core. Phycobilisomes (PBSs) are the main light-harvesting complex in cyanobacteria and red algae. In general, they consist of a central core and surrounding rods and function to harvest and channel light energy toward the photosynthetic reaction centers within the membrane. They are comprised of phycobiliproteins/chromophorylated proteins (PBPs) maintained together by linker polypeptides. PBPs have different numbers of chromophores, and the basic monomer component (alpha/beta heterodimers) can further oligomerize to ring-shaped trimers (heterohexamers) and hexamers (heterododecamers). Stacked PBP hexamers form both the core and the rods of the PBS; the core is mainly made up by allophycocyanin (APC) while the rods can be composed of the PBPs phycoerythrin (PE), phycocyanin (PC) and phycoerythrocyanin (PEC).	1.12572e-92

Protein sequences

>NC_008312.1|WP_011613202.1|5904038_5905364_-|hypothetical-protein
MSRLNSRAYKLLKVEVDKRAKEDLVGEVGKKIVMKRLDKLRFQSGETLKVEELSYIVKDQFPNFSDTVIQKAIKINKQPKILSKIMWIPAALVGMAGIVWVANLPYPMIRKPVSRVAPIVLLPSYINMDYNYREAIANIEQADQLINKATSSADINLGANKVALAQKHLNELPVWFLDFYPKRYCTFFSCSWKFTLDEFETARKQVGRMQAKVFQENNAQTFLAEAEQTIATAKQQYLEATTSTEKQQAIANWQSGIDRLAQIPPTTVAKKIAQPQLAAAKRDFEKEVGLADGNKLSFTFIEVAKKFGLKAAEAAQNGPHSDQRWQVIVDLWEQAINQLQKISADNPSYLAAQSKIAEYQLNLANVKMRLQAERDSGTAFKRGKDLIADWKKSAINNSDRGLLASKLQEIINQLENVKPETTFYQQAQELLKFAKDKQKNL
>NC_008312.1|WP_011613201.1|5900217_5901993_-|AarF/ABC1/UbiB-kinase-family-protein
MLNKKYIPTPLIEKKKKKKVKIVEKIDKRRVTTPYVIRRFIIYFLALQWRRFTGKANMEKTATQLREIFEDFGGFWVKAGQVLALRTDILPEPICDALQSLQSEALGFPFDIVRSTIESELGVPLKKVFAVFDEEPLAAASIAQVHTAVLRKKQIPVVVKVQRPGLEDAFQRDLNVIKGLVNLLIFLNIATYLGWGEFIAELDKTFKEELDFRYEASSTIRMRKSLKEHKVFVPKIYEKYSKRRILVMEFINGVMMSDYITALASQRSLAAKWEEENNIDRVKLGERLYLSLFRQLFEDNLFHADLHPGNIILLRNNKFVLIDHGSTGSLEAELRNTYLNYVNGLGEGNFTKAADYYIRFGVGIPKVDIDRVRVEMGRQFENWYVRSQVKGVPFRQKSLGGAIKGVTDVAFGYKIPTNWDFLKLTRSVLALDGSLQYLWPDIDVFEVINKYNKQARRRALVNNLRPENILKWVNQASDIVNQYNYLVLPEVRKRTNAYELTVNQFALSMVVILRRSSYLVLVAEFGALYVFLYQHYFQIIRPINIQMIDEIVSKFPYIPYLEWVGILIVVGLIFQVLLVCAKILGRKELNI
>NC_008312.1|WP_044136913.1|5899521_5899725_+|hypothetical-protein
MADGTMFVAKYKLYKSIKSNVKDGFNTDDSDNKDDYIFRYVISIAGTKPFSIFAAVFQDLSIFKTRP
>NC_008312.1|WP_155994488.1|5897085_5899005_+|NAD(P)-binding-protein
MMIETKRAIVVGAGSSGLIAAKELLDTGLDLTILEKEASLGGVWHKYCWKTSTLTSSKWMTEYGCYPAPKEYADFMKPEEMMEYLSSFTKHYGLEDKVHFGVQVKAIARSTDGKYDVITDGETYSGYDYVVISTGLHGEPVIRDVPGIEKFTGTIMHGFKYKDPEAFRDKKVVCMGLGESGIGISSEISSVAAKTVVAAGNFNFAPRVYPYSNKPFDQIQFWPMGQYIKDYQELLSAQMSWITRLPEPLRTAYANMHPWLRDLPKEWLPTAYVPHYWAGKYWPKPNNNFGDMSGNLTRPSTAPDDIIYLVHSGKITAKGKVERFDETGVYFPDGTREEVDMVVANTGFKPGAALIEFPDNWQYRHQELYKGCLHPDMPNLAFVGFVRPTIGSIPAMAEMQSRFVAQVFSGGYKLPEKEKLKKLIKKEADAHARKNPKMTERWPHIYFFDQWMEEMAELLGTQPKIWQHLSSWKQLQGFLFGAPMPIRFRQYGSGVVAGAKERYADRINQLYGTRPQSYIIPYLTISLFFPYILSLIISAVCYWGANLSPLISIGSGLLFYTLYMTVDLFRFVVGFLPITLPSLMALEQSLPWRNCDNDSMMFLMSFPEKDRMNYANPRVFENDGLPKSELLDREIAVKN
>NC_008312.1|WP_011613199.1|5894130_5895816_+|hypothetical-protein
MATTYQTLQKKPKAPKAPSTEYTWEQIVISHIWIIYCISFPYSYVGSKEYLQQLSTESVQRILANPRVKKLIGKWELVWGMSIYQFPGSGVNDNTLYIAKYNDNNPEKDTYVLSVAGTNMKSFYSILCEDGGVFSTKEWNNGQPWNSPPNFQSTTEPSISTGFTRTLDKLFNKTKDSNGTLVMEALQKITSSSSKPVDLIVVGHSLAGTMSPLVALALFERQSEWDSKGIATIKEVWAIAGPTPGNPALQEYYTSKLGDKTQSLWSELDIVPNCFAREGMTGVASLYEPDIPSSPLVEIIMQAFNKSIERHNYQHIIPQPAYTGKVNNDFRIENINKYPEVKEFIADQCAAMLLYAFLSSLEDMSNVIEDIPFVGRAFEPLKGKLDYLVKSSTFIVSKFFAQVIDAGVTVVLIEDKIESVFEEVLDHIGLTVPISVVMSVLPGDLILGHNIINLMDWYMQFYFQHVDQYVGYYGVDELYGIKADITSEVEARLGKEENKKQEANTILLNYGKAKNDDIKDLYRGEGKLLDGISDVVAELKQSGDVEKNAQPLVVIVEKKRD
>NC_008312.1|WP_011613198.1|5892399_5893881_+|NAD(P)/FAD-dependent-oxidoreductase
MNNQISSNPDQNLEIAIIGAGISGLCMAINLRKAGITTFKIFEKSDNVGGTWHDNTYPSCGCDTPSILYSFSFEPKSDWTRHFPKQPEILEYLEHCSKKYDIRKHITFNTEISSAFFDSEKNIWRIYSASGEEFSANILVSGCGQLNKPKIPHLDGLETFSGTQFHCARWNHEHDLKDETVAVIGTGASAIQFIPIIAEQVKKLIVFQRSAPWIAPKPDFKFTNFIHWLGKSFPFILRFYRWLLYLVLEYFVVYLTIKQNTIVGKLVSTFLNFQREKIIKDENLKSILKPNYEVGCKRILISNDYYPALQLPNVEVVAQDIKGINQNQIITKEGREYPVDTLIFATGFDTKLLSSIKIVGLNNQLLQDKWQDGAEAYKGIMIPEFPNLFMLYGPNTNTGTQSIIFMVECQVNYIISCIKMMQNKSQKYLDVKPDINSEYNQKLQVAASQTVWNSGCSSWYKTKTGKIVNNWPFSTVRYWLTTSQADPKDFNFS
>NC_008312.1|WP_011613197.1|5891767_5892256_+|lipocalin-like-domain-containing-protein
MSDNLISKDNLVGTWKLADFYTIDSKQKIAYPFGKNPTGYLIYTENGYMSVLIMTTNRPLLGLSVEEMQDLKSPKLGIKLIANLGKYIKATLRYFSAGRNCLSYSGRYEIRDSTVIHHIEVSLVPDWVGLDFERNVEFSEGQIILTNMLRDTSFNLTWKLVP
>NC_008312.1|WP_011613196.1|5887336_5891401_+|type-I-polyketide-synthase
MEPSSETIQLSNQQRLLLAVKQATAKLNEIETATTEPIAIIGTACRFPGGVDTPESYWEFLRESIDGRVEIPKERWDNDLYYNPDPEAPGQIYVRHGYFLQQPVDQFDPAFFSISGVEANKMDPSQRLLLEVTWEALENAGISPRSLKNTDTGVYIGQCFNDYALIGINALPNNFGDFYLGLGTAMNTSSGRVAYAFGLQGPTFTLDTTCSSSLVTLHIACQSLRSGESNLALVGGVNLMLHPNVTHGFCKGRALSPDSRCKTFDASADGYARGEGCGIIVAKRLRDAVADGDRILALVKGSAINHDGPSSGLTVPNQQAQKKVIRQALVNAKVDPLAVDYVECHGTGTSLGDPLEVKAIDEVYCRERSKDDPLVLGAVKSNVGHLEAAAGVAGLIKIILALQNKEIPPNLHFNQPNPQIDWDKIPVQVATSVVPWEKPGKPLLAGISGFGMSGTNAHVILQEAPEQVKSKNDTDRSLHLLTLSAKTKKALEKSVVRYQNYLAQENNGNELADICYTANTGRTHFNHRLAVIAANQAELLEKLSAGLTGEEIFSGQVSSSSLPKVAFLFTGQGSQYVNMGRRLYEQAPVFRQAIDQCNQIFTTIVEEQAESEEMSLLDVIYSDTTEDSDSSPLHQTAYTQPALFSIEYALAKLWQSWGIQPDVVMGHSVGEYVAATIAGIFSLEDGLKLITARGQLMQQLPSGGEMVSVMASESKIRPLLKNYTDQVAMAAINGPASVVISGESEGVRAIATKLKSERIKTKQLQVSHAFHSPLMEPMLSEFEAIANQIDYSIPRIPIISNVTGAKADSSITTAKYWVNHVRQPVKFAQSMNALHQQGVDIFLEVGAKPILLGMGRRCLPEDVGVWLPSLRPNVDEWQQILSSLSELYVRGAKIDWSGFDGDYQRQKVTLPNYPFERQRYWIESEKSGLSGSTVSQITETATETLTKQLAETGNLSASELKLVPKILDLLKQQQLKSVTESDQKYTELEDLVSPSSIIDIEKFQAASRKEQKLMIVEYLQELAMKVLQLNTSEVLDPNESVLELGFDSLSVVELRSKVEKQLAVTIPASLILQGPSIMELAEALVEQLTNSGSSDQGPVKSKKGSGWIAYHKPKLNASTRLFCFHPWGASASMYQQWSDALPPEIEVLPIQLPGRQRRIQEKPFTDFASLIEVLADFLSPYLDKPFAFFGHSMGGFIAFELAYFLEKQYNLKPRHLFLSGVVPPSDNTFLEKIGSLSETERLNYLLEISEIPESITEDSSLFHELMNIFKADFQLLQSYRYLEKKPLDFPISSFSGVDDYTISDRQLNNWSKYTTSNLKIDRIPGKHMFMFLKDSQKLLLELISQELLPQLIAQ
>NC_008312.1|WP_011613195.1|5881442_5887172_+|type-I-polyketide-synthase
MNQPEEPQQYNDNEIAIIGMSGRFPGAKNVEDFWDNLKNGVESISLLSDKQLSKSGVAPEILNNPNYVKVNSMVSDIDMFDANFFNYSPREAEEIDPQQRLFLECAWEAIESSGYNPENYEGSIGVYAGGGLPTYLMYNLEDQDFILLGNRYFTQMVGNDKDYLATRTAYKLNLTGPALNIQTACSTSLVAVHLACQSLLNGECDMALAGGVSIQIPQNVGYLHQEGLIGSHDGHCRAFDARSSGTVFGNGVGVVLLKPLQDAIADGDCIHAVIKGSAINNDGSLKLGYTAPSVDGQAAVISEAQAVASVTPETITYIEAHGTGTELGDPIEIEALTKAFSEHTDKKQFCAIGSLKTNVGHMNTAAGIGALIKTVLTLKHNLIPPSLHYEKPNPQINFSDSPFYVNSTLSEWKRNGTPLRAGVSSFGIGGTNSHVVLEEAPSQVKEEDDLQRPVHILTLSAKTPTALADLVDSYHHYLETNLDLDLGDVCYTANTGRVHFNHRLAVVAEKQTELTEKLRQFKLEDKVEGICSGKLLINATAPKVAFLFTGQGSQYVNMGKELYEQAPVFRAALDECEEILEELGVNSILEIIYPEGGETSPLDQTAYTQPAIFAIEYALAKLWESWGIKPDVVMGHSVGEYIAATVAGIFSLEDGLKLIAARGRLMQQLPAGGEMVAVMASEAKVKKLLRPYAEKVAIAAINGPKSVVISGEATAVREIVSSLESEKIKTKQLQVSHAFHSPLMEPMLAEWEAVAKELTYHQPEIPVISNVTGTIADKSITTAKYWVDHVRLPVRFAEGMDALQKQGVEIFLEVGPKPILLGMGRRCLPKDVGVWLPSLRPEHIPLQSSLESARSEDFSQMLSSLGELYVRGVKVDWVEYDGEYSRQKVILPTYPFQRQRYWIDNYSRGRNSVSVSSNNGFVTEEGTSNPLLGRKLLLPFAQQFRFQTKLTPEFPSYVKDHRYYGKIVVAGASHIVLGLLAGKEALNSDSCVVENIEFLQILGADETSSRTVQILLDQEKETEYTYQLISCEAGTEYDPSTVWTVHAKAKVRSVNNSELPKENIDIAAVKNRCIQSLSSDEYYSTALEPMKGDFHLGPTFQWTEQAWISSTEGLVKVKAGENNEEMQEYWPHPGMVDSGIVPVALLSILRELSQNTENNGNGKKNAIDSEMEIPTYAFAGAKSFKFFDNFDIDDDLWYYTKIDESSSYDRGELLGETYLLNGDGKVLAEYSGIDFRQLSRKLLLRSFGLDFSQWYYQTEWQPAALMPGETQETGTYLLFCPTGESNSKLKEWSDSLNSQLLDQGHQCIVVYPADSYKKLSSEGKKQIIQLSPTQPEHFQKLLDEVNELTEELPLKGVIHLWSLDTDVEELTKTEEIICGSIINFLQGMRSLEKLPPLLLVTQGASLEVRSKESGVSINAQPQQALLWGVGKVITMEYPQLDCRCLDLDPNADEQETLKVLLDEVANHQTSTSVENQIRYCQGKRQVARLTQPRLDTDAKLAIQTEASYLITGGLGALGLEVAQLLVQQGVKSIALVGRNSPSETAQESIQELEAAGTQVSVFLGDVSVEKDMVNIFQKIQTSLPPLKGVIHAAGVLDDGFIQQMTWQQFTKVTAPKVTGTWNLHKLTKDIPLDFFVCFSSLASVLGSPGQSNYAAANAFMDAVAQYRQNLGLPGLSINWGPWANVGIAARMGAQQQGRLQSQGLQGIQTEQGLQALEEVLATDEAQIAIFNIDWPHLLSQFGQMTPAFLSEIASQHPLQGKANQGPKQRELLEQMKVATTDQRQRLMVDYLIGVVAKVLRRGKNDLPDPEEGFFNLGMDSLMALDFGQMIQVDLGITLSSTSTFEYPNIQALAEYLEEIIPKVDEKEAEYETDDTAIDAESLITEISQLSEDKMDEAIDEALTQLYQFI
>NC_008312.1|WP_011613194.1|5876967_5881329_+|AMP-binding-protein
MKLTQILSQISSQGIKLWAEGDELKIRAPKGTLTAEIRDLLSQNKLELLQLLQQKSSNISATSVPLVPVGRDKDLPVTYQQERLWTIDQLMGNKLNLNVSTALRIEGLIDVQLLQKSWNEMMSRHETLRTTFSFAEGSLIQVVLPSLDSEISVVDYQGLSKTEQASVIQEAIEQEAQQYFDLSEGPLLNVKLFRCSEREGVLLLVSHHIISDGLSHNFLFREHILLYDSYLSKKPSPLEELDIQYGDYSVWQRQWLQGEVLQKGIDFWKKELADISTLYPVPSDIFQVSPGFKAIKKTFSIPNNILSLVQKVSNQYSVTPVVIFLSVFYVLIFQYSLKQDIVVGLPVSGRLHHKLQSAVGYFTDTILLRAKISDNFITFKELLNKVKEITIKAYANQHIPLNFVAEFLNQQNNQQYRNLFQIFFDYIDFGGEDKIEYPNLTGTSIEEKFPSDIDLFFLLLKFEQELKGSFSYNPELFEEETITALIDSYLLLLEKAINAPETQINDLEISENLAKRKTEIHSQSRKINLIETGLKSISEVKESAVLTRDNQLVAYVVITDDYSVEKVQSFLESHLSSEFLTDAYIPVSTLPKTESGEIDETALTSLEVIDSELINRWEEKLRSHPEIEEVAVVVQRKQAYPVIPVIQETTVEKNGKDNTKDLKIAEENIADTTPAEVDEVAASVEFETWADLLPGTNEPAIYSTDGRKPLTHAQLKDFVQSPPDKASLSYLGIKITDRVCAATPNGPEAAIAFLSLAQQCVFAPISTSLTEKQVQFELEDLGAVALLLQKGEANSSDNAKLKACAESLGVRVIELIPDASVCGLFSLEEITTNKEEHQPITEGNNKPTRDHIALVLHTSGTTRKPKTVPLTHGNLTAGSLTISQTIQLTPEDTCINIMPLFHIHGLSVNILASLLAGASVLCMPGLYATEKGVSDFFEWLKPDEGSDRKKVTWYSAVPTMHQAILEYAEQALAETGKAPEHSLRLIRNCSAALLPAIADRMAKAFKCEVLPTYAMTESMPICSPEVGKGLLKRGSVGRAAGPKVIIGDVKLDGKGKSVLSVLEPYAEGEVMVQGACVTAGYELREWMDYNPNKEAFIDGWLRTGDKGYKDKDGYVYLVGRFKEIINRAGEKISPMTVEDVLQRHPAVGQVVVFAAPHELFGEVVGAAIVPVPNQTRPTLAALRQFAMKQKELETQYLPECLVWMNAIPKGLTGKPARIGLAKRLGIPILTTDVTASPRTFVATKGGDGKYVLEILESQIENGKGSCQSLQQLTVYFTSKTTEFSLSQLSEFEVRDRFGTLSQIMPYAFVQLDTLPLTSDGKIDRKRLQNPEKDGGSQIVQQGNETEQKIAAIWKEVLQIEEVGIYDNFFELGGKSVLLIQVYAKLQEIFDMNNLKVVDLLANPTVYSLSQFIINGGTAESNKQSQVSYQKRLTKRLSKKSERGNMRKKLRSQK
>NC_008312.1|WP_011613204.1|5917265_5918024_-|lipoate--protein-ligase-family-protein
MFWRLIPLLTTTGKLQMAIDEWLLQQHLQGNIPPTLRFYIWQPVAISLGYHQKSYPEYWQNLTRQGTPIDIVRRPTGGRAVLHQGDLTYSLISSGFSGSPIESYRAICEFLIWGWRSLGIDLAYGSTGRGYIKNPNCFGTSTGADLVLPDGRKFIGSAQLRKKGAILQHGSMMLEPDIEFFRYVFNSEVFSGVSDIFTSFLSTNDMGESLINKIIEVLIIAASECFKIQLITEPLSDKEWLEIHNFANTNLC
>NC_008312.1|WP_011613205.1|5918585_5919080_-|YbjN-domain-containing-protein
MTTNNPETVSVDNASIEEANINELTEDETSLGYIENIETVIAGMAEEQKVMVAQNEAGHLWKFKYGSVDVYVRLTGETDDDNLTVWSYVLKLPAKNEPELMRKLLQMNWLSTMESHFAIVDNQIVVVATRTVAELSPGEISRAITIVATLADDNDELLVAEFGQ
>NC_008312.1|WP_011613206.1|5919176_5920268_-|class-I-SAM-dependent-methyltransferase
MSDTITKFTYQTFQKSKAGLALAHKKISTYLQGFIAPNLRLKTKPLSAKVIQKIQQRMDEIIEKDLADGEKGIYPTNIIFDHPWSDFFSFYLNIWLELPQVWERIQQKKYQYFSPQIKIQGYPSYYLQNFHYQTDGYLSEMSANLYDLQVEILFNGTADVMRRRVLAPLKMGLEKLFSGQNLDAIAPQKLRVLDIACGTGRTLKLIRASLPKASIYGIDLSANYLKKANKLLSEELGELPQLLQGNAENLPFQEKYFQGITCVFTFHELPPMVRTKVLEEAFRVIQPGGVFVICDSIQTCDEPDFTGMLENFPAMFHEPYFKNYITDNLEERLEKAGFVNIATEVHFVSKYWVAYKPDLNIDN
>NC_008312.1|WP_011613207.1|5920769_5922191_-|type-I-glutamate--ammonia-ligase
MVKTAQDVLNWIKSQDIQVIDLKFIDLPGIWQHLTVHQSQIDESSFTDGVAFDGSSIRGWKSINESDMMMVLDPTTAWIEPFMAEPTLSITCSIKEPRTGEWYSRCPRVIAQKAVDFLKTQGIGDTVYFGPEAEFFVFEDARFDQTENKAYYYVDSIEGRWNSGREEDGGNKAYKPDYKGGYFPVPPTDTMQDLRTEMLLTMAKCGVPIEKHHHEVATGGQNELGFRFGKLVEAADNLMIYKYVIKNVGRKYGKTITFMPKPIFNDNGSGMHVHQSIWKDGEPLFWGDGYANLSKMALHYIGGILKHAPAILGFSNPSTNSYKRLVPGFEAPVNLAYSQGNRSASVRIPLTGTNPKAKRLEFRCPDATCNPYLAFAAMLCAGIDGILNEIDPGPSLDVDIYDLSPEELSKIPSTPGSLEGALEALEKDHEFLTAGGVFTEDLIQTWIDYKMENEVKPMRLRPHPYEFSMYYDC
>NC_008312.1|WP_011613208.1|5922959_5923469_+|allophycocyanin-subunit-beta
MQDTITSLIKNYDIKGRYLDQNGIDQLKSYFETGTARVQAATLINSQAASLVKQAAITLFAEQPELIRPGGNAYTTRRYAACLRDMDYYLRYATYALVAGNTDVLDERVLQGLRETYNSLGVPIGPTLIGISILKELIKSKVEAAGIQTGAFLAEPFDHLINELAEKDI
>NC_008312.1|WP_011613209.1|5923743_5924598_+|TlyA-family-RNA-methyltransferase
MPKQRLDVLLVERNLCSSRQKAQVLIRAGEVMVNQQIVDKPGTEVDLESNIKVKQKSLYVSRGGYKLAKALEYFSISISNRICLDGGISTGGFTDCLLQAGAKLIYGIDVGYGQVDWKLRNDSRVILKERTNIRYLTPQELYGDSLILNYELQENTKEIYPSLAVVDVSFISLAKILPALWELLIPPRETILLVKPQFEVGKERVGKKGVVRSYNDQAEAIFQVCCSANNLGWKYAGLTWSPIQGPAGNIEYLLWLNLDSELLVDRSAIADITKLARQKFNHNL
>NC_008312.1|WP_044136915.1|5925253_5925670_+|hypothetical-protein
MIQADNNFESQYQQQLEKLSMYHFSPVPPPPGIDIPRKLHPLVSTHQITGHKGLYLGSDTSTIQGLEDKLDLAKQYWVELFEKILNFTPFYSYLWQAGDIVFWNNSQVMHTGKAYKYTKYQRIALRIGVVNNGDNYNC
>NC_008312.1|WP_011613210.1|5926432_5927119_+|hypothetical-protein
MLIRKISIYFIFFIKLSIYIFCTSFIFSIIVSAKIISIKLADNFLYNLILFGDFLRGIEIVEIFNIIAFAVVGMGFGLATVLLPKYLGRYVSTILLVILVPIIFITTQIVRYDIWVEQVAENEKLSFNQAELLIDSFLNKRVGKDGIYGFYLYTAKFPVLPDKKVQINNLDRLEKSVNSKFVRLIGVPPGVIYWTMSLCFWVIRIFYFVIAVVTTIFHFREGLRIVKC
>NC_008312.1|WP_011613211.1|5927247_5928693_-|DUF697-domain-containing-protein
MILLFPTKLSKASLTLNHSNIYPEIITENSQSTESYCKQSKIHWKRAKASLQRALNRYSVWQNASYKTTNPEFSSTVKTQLELLKSNIDKLDQGVIQIAVFGLVSRGKSAVLNALLGEKILETGPLNGVTKWPRSIRWTPNIFVNFHQQEVAKVDLIDTPGLDEVADQVRGEMAKEVTRQADLILFVVSGDITRTEYDALYELKKSKKPLILVFNKIDLYSEVERQEIYKNLQNIAVFQSGELDNIYPTFEVVMVAAEPTPLPVIIEMPDGKVTHEWETPSPKIDELRQKIITILEREGRSLLALNALLQARKAEVSIAQKTVKIKQNEADDLIWDFAKYKALAIAFNPITIIDVVGTTVIDLALIRSLSRLYNLPMTSYEAGKLWKIIIFSAGGILLGDLGTSLLLGLGKVNIISYTGVAITQASVAAYGTYAIGSAAKVYLENGCTWGDLGQDIVIQDILSQMEPDTIIYRLQQELFNK
>NC_008312.1|WP_011613212.1|5931919_5933398_-|DUF697-domain-containing-protein
MAVKLKRPILVGGIGLSLLLWLLSEVQNFITDNSEPTILGIIVVSLGVWLLKRPKYLPSHKPSIIVSPTKQAAEEAIGLLSITIDKVSMTVEGINNSEKISNDITQLHQQVKIITQELERQELSIVITGNKGVGKTTFTEILKSQWNSKKSPKIKVVDITWEPEWATNNEYAKVNPLSPYDLILFLTTGDLIDSEFQALSKLTTLGQRFILIWNKQDLYLPDQKPQVIQKIKETLSTINSEKNLVGISVKPNPIKVRKYQQDGTIQESIEQPLPEISQLTEKLNQLLEEEREKLVWATTIRKAEIFRLEAQNILNKIRKERALPVIEKYQWIAAATAFANPVPALDLLATAAINTQLVVDLSAIYEQKFSIEKGKQVAGTMAELMLKLGLVELSTKTLTTLLKSNSLTFVAGGAFQAVSAAYLTRVAGMSLVEYLTTQADTNSVNIDQLGTIIQGVFSKTQENNFLKSFVTQVMSHILPQGKQLEFVSSPAQ

Crispr_ID: NC_008312_41

• CRISPR_ID: NC_008312_41
• CRISPR_location: 6337044-6337430
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 4 spacers

Consensus repeat of NC_008312_41

Consensus_repeat	Method
CAAGTAGCTTCTATGGTGTCCCAAGAA	PILER-CR

spacers of NC_008312_41

>41.1|6337071|63|NC_008312|PILER-CR
GTTCATAATTCCTTGCAGGAACAGTCACAACAGCAAGAAACTCAAATTCAACAACTAGAGTCA
>41.2|6337161|63|NC_008312|PILER-CR
GTATACAAAATTCTACAGCAGGAGTCTCAAGAACAAAAAGCGAAGTTGGAGCTGTTGGAAGAG
>41.3|6337251|63|NC_008312|PILER-CR
ATTCACGATTCTTTGCAGCAGCAGTCACAACAGCAAGAAACTCAAATTCAGCAACTAGAATCA
>41.4|6337341|63|NC_008312|PILER-CR
GTATACAAAATTCTACAGCAGGAGTCTGAAGGACAAAGAGTCAAGTTGGAACTGTTGGAAGAG

CRISPR arrays and Neighbor proteins around NC_008312_41

CRISPR arrays

The CRISPR arrays of NC_008312_41

>merge|NC_008312|41|6337044-6337430|PILER-CR
CAAGTAGCTTGTATGGTGTCTCAAGGAGTTCATAATTCCTTGCAGGAACAGTCACAACAGCAAGAAACTCAAATTCAACAACTAGAGTCACAAGTAGCTTCTATGGTGTCCCAAGAAGTATACAAAATTCTACAGCAGGAGTCTCAAGAACAAAAAGCGAAGTTGGAGCTGTTGGAAGAGCAAGTAGATTCTATGGTGTCCCCAGAAATTCACGATTCTTTGCAGCAGCAGTCACAACAGCAAGAAACTCAAATTCAGCAACTAGAATCACGAGTAACTTCTATGGTGTCCCAAGAAGTATACAAAATTCTACAGCAGGAGTCTGAAGGACAAAGAGTCAAGTTGGAACTGTTGGAAGAGCAAGTAGCTTGTATGGTGTCCCAAGAA

>NC_008312|41|4|6337044-6337430|PILER-CR
CAAGTAGCTTGTATGGTGTCTCAAGGA	GTTCATAATTCCTTGCAGGAACAGTCACAACAGCAAGAAACTCAAATTCAACAACTAGAGTCA
CAAGTAGCTTCTATGGTGTCCCAAGAA	GTATACAAAATTCTACAGCAGGAGTCTCAAGAACAAAAAGCGAAGTTGGAGCTGTTGGAAGAG
CAAGTAGATTCTATGGTGTCCCCAGAA	ATTCACGATTCTTTGCAGCAGCAGTCACAACAGCAAGAAACTCAAATTCAGCAACTAGAATCA
CGAGTAACTTCTATGGTGTCCCAAGAA	GTATACAAAATTCTACAGCAGGAGTCTGAAGGACAAAGAGTCAAGTTGGAACTGTTGGAAGAG
CAAGTAGCTTGTATGGTGTCCCAAGAA

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_008312.1|WP_011613437.1|6321623_6322703_-|fructose-bisphosphate-aldolase-class-II	unknown	unknown	gnl|CDD|181691
NC_008312.1|WP_011613440.1|6328588_6328903_+|hypothetical-protein	unknown	unknown	unknown
NC_008312.1|WP_011613442.1|6331606_6332476_+|photosystem-I-reaction-center-subunit-XII	unknown	unknown	gnl|CDD|366093
NC_008312.1|WP_011613449.1|6342796_6343378_-|Chromophore-lyase-CpcS/CpeS-4	unknown	unknown	gnl|CDD|312763
NC_008312.1|WP_011613439.1|6325133_6326900_-|CapA-family-protein	unknown	unknown	gnl|CDD|378215
NC_008312.1|WP_011613443.1|6332732_6333494_+|photosystem-I-reaction-center-subunit-XII	unknown	unknown	gnl|CDD|366093
NC_008312.1|WP_011613445.1|6335522_6335828_+|hypothetical-protein	unknown	unknown	unknown
NC_008312.1|WP_011613444.1|6333691_6334213_+|Chromophore-lyase-CpcS/CpeS-3	unknown	unknown	gnl|CDD|312763
NC_008312.1|WP_011613447.1|6338711_6339935_+|glycine-betaine/L-proline-ABC-transporter-ATP-binding-protein	unknown	unknown	gnl|CDD|226643
NC_008312.1|WP_011613438.1|6323890_6324538_+|hypothetical-protein	unknown	unknown	gnl|CDD|379232
NC_008312.1|WP_011613455.1|6351648_6352359_-|type-II-secretion-system-protein	unknown	unknown	gnl|CDD|225076
NC_008312.1|WP_044137858.1|6329322_6330939_-|MBL-fold-metallo-hydrolase	unknown	unknown	gnl|CDD|224157
NC_008312.1|WP_081432567.1|6350461_6350971_-|hypothetical-protein	unknown	unknown	gnl|CDD|227305
NC_008312.1|WP_011613451.1|6344999_6345869_-|HIT-domain-containing-protein	unknown	unknown	gnl|CDD|223611
NC_008312.1|WP_011613450.1|6343753_6344590_+|pentapeptide-repeat-containing-protein	unknown	unknown	gnl|CDD|224276
NC_008312.1|WP_011613436.1|6319090_6321223_+|hypothetical-protein	unknown	unknown	gnl|CDD|224276
NC_008312.1|WP_011613453.1|6349314_6350373_+|GTPase-ObgE	unknown	unknown	gnl|CDD|237048
NC_008312.1|WP_011613456.1|6352421_6353438_-|type-II-secretion-system-protein	unknown	unknown	gnl|CDD|227132
NC_008312.1|WP_011613452.1|6348238_6348964_+|nitrogenase	unknown	unknown	gnl|CDD|369150
NC_008312.1|WP_044137859.1|6340308_6342288_+|glycine-betaine/L-proline-ABC-transporter-substrate-binding-protein-ProX	unknown	unknown	gnl|CDD|270356

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_008312.1|WP_011613437.1|6321623_6322703_-|fructose-bisphosphate-aldolase-class-II	gnl|CDD|181691	PRK09196, PRK09196, fructose-bisphosphate aldolase class II.	0
NC_008312.1|WP_011613455.1|6351648_6352359_-|type-II-secretion-system-protein	gnl|CDD|225076	COG2165, PulG, Type II secretory pathway, pseudopilin PulG [Cell motility and secretion / Intracellular trafficking and secretion].	4.18643e-11
NC_008312.1|WP_011613442.1|6331606_6332476_+|photosystem-I-reaction-center-subunit-XII	gnl|CDD|366093	pfam00427, PBS_linker_poly, Phycobilisome Linker polypeptide.	3.71039e-71
NC_008312.1|WP_011613439.1|6325133_6326900_-|CapA-family-protein	gnl|CDD|378215	pfam09587, PGA_cap, Bacterial capsule synthesis protein PGA_cap. This protein is a putative poly-gamma-glutamate capsule biosynthesis protein found in bacteria. Poly-gamma-glutamate is a natural polymer that may be involved in virulence and may help bacteria survive in high salt concentrations. It is a surface-associated protein.	1.69705e-87
NC_008312.1|WP_081432567.1|6350461_6350971_-|hypothetical-protein	gnl|CDD|227305	COG4970, FimT, Tfp pilus assembly protein FimT [Cell motility and secretion / Intracellular trafficking and secretion].	3.15479e-07
NC_008312.1|WP_011613443.1|6332732_6333494_+|photosystem-I-reaction-center-subunit-XII	gnl|CDD|366093	pfam00427, PBS_linker_poly, Phycobilisome Linker polypeptide.	1.48285e-73
NC_008312.1|WP_011613456.1|6352421_6353438_-|type-II-secretion-system-protein	gnl|CDD|227132	COG4795, PulJ, Type II secretory pathway, component PulJ [Intracellular trafficking and secretion].	0.000218929
NC_008312.1|WP_011613444.1|6333691_6334213_+|Chromophore-lyase-CpcS/CpeS-3	gnl|CDD|312763	pfam09367, CpeS, CpeS-like protein. This family, that includes CpeS proteins, is functionally uncharacterized.	7.16503e-80
NC_008312.1|WP_011613449.1|6342796_6343378_-|Chromophore-lyase-CpcS/CpeS-4	gnl|CDD|312763	pfam09367, CpeS, CpeS-like protein. This family, that includes CpeS proteins, is functionally uncharacterized.	1.12133e-87
NC_008312.1|WP_011613447.1|6338711_6339935_+|glycine-betaine/L-proline-ABC-transporter-ATP-binding-protein	gnl|CDD|226643	COG4175, ProV, ABC-type proline/glycine betaine transport system, ATPase component [Amino acid transport and metabolism].	8.74065e-164
NC_008312.1|WP_044137858.1|6329322_6330939_-|MBL-fold-metallo-hydrolase	gnl|CDD|224157	COG1236, YSH1, Predicted exonuclease of the beta-lactamase fold involved in RNA processing [Translation, ribosomal structure and biogenesis].	1.56852e-70
NC_008312.1|WP_011613451.1|6344999_6345869_-|HIT-domain-containing-protein	gnl|CDD|223611	COG0537, Hit, Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases [Nucleotide transport and metabolism / Carbohydrate transport and metabolism / General function prediction only].	9.71424e-30
NC_008312.1|WP_011613450.1|6343753_6344590_+|pentapeptide-repeat-containing-protein	gnl|CDD|224276	COG1357, COG1357, Pentapeptide repeats containing protein [Function unknown].	1.29693e-34
NC_008312.1|WP_011613436.1|6319090_6321223_+|hypothetical-protein	gnl|CDD|224276	COG1357, COG1357, Pentapeptide repeats containing protein [Function unknown].	3.74458e-34
NC_008312.1|WP_011613453.1|6349314_6350373_+|GTPase-ObgE	gnl|CDD|237048	PRK12299, obgE, GTPase CgtA; Reviewed.	0
NC_008312.1|WP_011613438.1|6323890_6324538_+|hypothetical-protein	gnl|CDD|379232	pfam13517, VCBS, Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella. This domain of about 100 residues is found in multiple (up to 35) copies in long proteins from several species of Vibrio, Colwellia, Bradyrhizobium, and Shewanella (hence the name VCBS) and in smaller copy numbers in proteins from several other bacteria. The large protein size and repeat copy numbers, species distribution, and suggested activities of several member proteins suggests a role for this domain in adhesion (TIGR).	1.00165e-06
NC_008312.1|WP_011613452.1|6348238_6348964_+|nitrogenase	gnl|CDD|369150	pfam06967, Mo-nitro_C, Mo-dependent nitrogenase C-terminus. This family represents the C-terminus (approximately 80 residues) of a number of bacterial Mo-dependent nitrogenases. These are involved in nitrogen fixation in cyanobacteria. Note that many family members are hypothetical proteins.	8.32284e-57
NC_008312.1|WP_044137859.1|6340308_6342288_+|glycine-betaine/L-proline-ABC-transporter-substrate-binding-protein-ProX	gnl|CDD|270356	cd13638, PBP2_EcProx_like, Substrate binding domain of Escherichia coli betaine transport system-like; the type 2 periplasmic binding protein fold. This group includes the periplasmic substrate-binding protein ProX. ProX from the Escherichia coli ATP-binding cassette transport system ProU binds the compatible solutes glycine betaine and proline betaine with high affinity and specificity. Many microorganisms accumulate these compatible solutes in response to high osmolarity to offset the loss of cell water. The ProX belongs to the type 2 periplasmic binding fold protein superfamily (PBP2). The PBP2 proteins are typically comprised of two globular subdomains connected by a flexible hinge and bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap.	4.19941e-177

Protein sequences

>NC_008312.1|WP_011613445.1|6335522_6335828_+|hypothetical-protein
MLPPTAEKKLQGWIRSRHIICSGNFFLFETVEYSTIDRFTVCVRALGGSLISVKPIKKIWIGNHRKVVLYQAKASLHTPHHDLKQYWVKYGGFYTRFDERG
>NC_008312.1|WP_011613444.1|6333691_6334213_+|Chromophore-lyase-CpcS/CpeS-3
MDIEEFVERSIGCWRSQRSGHSLALSHFEEVRSTIDIVDLPKTDHEVKNLCDSSGVDIENAVSPFKMSWEGESDWDENEIIKGSCVLVPIPEDDNLKKGKLLRSQGYAETVSAVGEYYITEDDTFVLYTEYESAAAEEKIWFHTSNLRFRVSLIKTSDGNGVLTASFSSEIRS
>NC_008312.1|WP_011613443.1|6332732_6333494_+|photosystem-I-reaction-center-subunit-XII
MSLWVEKIDPIELRWNATQDEKQAVIRAVYKQVLGNIHVMESQRLISAESLFIGGEFSVRQFVNMVAQSDLYFSLFFESCSPYRFVELNFKHLLGRAPQDQAEISQHICIYNEKGYEAEINSYTDSYEYLQNFGENIVPYPQGTSTVVGMKNITFNRTFALERGNATSDRNKPSQLTLDLGANLSTKIQKPATVGGPYNNRVKRFQISVTKTGIGPVVKKSATTYTVSYEQLSSKINSIQRTGGKILKITEVP
>NC_008312.1|WP_011613442.1|6331606_6332476_+|photosystem-I-reaction-center-subunit-XII
MVFGPASQLGVSLFEDTEPVELLPGRSSEEIETVIRAVYKQVLGNAYVMESERLTVPESKLKEGTITVREFVRQVGRSDLYRSRFFDPCPRYRSVELNFKHFLGRAPDGYDEMKLHSNLLDEGSFEADIDSYIDSDEYSSAYGENIVPYYRGYKTQTGKKMVGFTHIFQLLRGASSSDLKGSLSGNSPALNKYVIQETPLAVVPPSGGSDGWSFQDTPLGARSRHGVGASSSGKVYRVEVTAYRSKVVNRVSRFRRSNQVFLVPFDQLSKEYQRIHRQGGVIASITPIS
>NC_008312.1|WP_044137858.1|6329322_6330939_-|MBL-fold-metallo-hydrolase
MNLECLAYSVGHADDGICLLVRIGIHRILLDCGITNISLLTNETKQQLPADIVLCSHAHSDHAQGLLALHRSFPDLPIYASEATTKLLPLNWPELTICEVPDFCQPLPWHSPIELCSGLTVELFPAGHLPGATAFLLTYTQGNRTYKLLYTGDFFLSKSRLVEGLPLAYLRGLKLDVLIVEGSYGTAHYPHRRQLENNLAERIYEAIAFGTSVILPTPPLGLGQELLMLLRSHHYFTGRDLDIWVEEKVARGCDLYLQLLPQFPTTVQNFAQHQPLFWDEKVKPRVLRRSPGKLPDKELPYILIADKDTDLRQYIINQDNSVLILLPEQPGKTSQELDFAYTETYLLTDHCDGLGTTQLIHNLRPQHVIFVNGSPSYLADLTNLEELRNRYQLHSPANGTLVDLPIGETFIVPTSLETNYEGELNELNTEVIISLPQSITNDSRWSTFSDTGLVEVRWQGEELVVRGISQRELLSQTTDRLSSPDLNCCGNCLHYRGQRCSNPVSALYGFKVTFDGYCPMFESVHFHFPSTEETDKTN
>NC_008312.1|WP_011613440.1|6328588_6328903_+|hypothetical-protein
MLQRKIYQLCCDGREVCIFLRDQQRWIEKAKILDIEGDLVTIRYETDEEDEICSWEEMVRLESIGAITQKLASVPKADIDLLVSEDCPEAEQIRNQYPESNQQE
>NC_008312.1|WP_011613439.1|6325133_6326900_-|CapA-family-protein
MNYIPNLTQKSLFELASSGDFQAISQWINKKLKPQGISARIAKENTGYLEVLVEFQTQPPVDRLIKFICYQLSQLNYPTLEKVKIVGRLSGSPNILWKHSVRINSHAKKNFNKQSNFVNKSDNLQFQTFRYLILLSSAVAAFIIGILVSYYSVLVRNSTSGQWVETAIEKVRVVEHRKVQNSQDPMVTLMFGGDVNLSNQVSNLVKRDYKLPFAKMNEYRAADLSIVNLESPLTRSTLNSRTQQQKSTVNPSYVKALTSGGVDLVNLANDHTLGYEQKSLLETIETLENAGIHSLGAGKTEEEARRPKIFEVKGQKIAYLNYYDTDIQPTTESVYVNSRNKDRLSSDIQILKKQVDWIIVNYHWGVQLSEYPGDWQMNIARMTIDQGADLVVGHHPKVLQGAEIYRGRPIIYSLGNFIFGDTSNKESDYDTAVLKVSLKPGKMKIEFLPVVVSKYQPHIVKGEKGKEILKHIAQISSIFHQPMRTPIIINTINDDFNFVGIDSFPREENSKTFSTPILPELPLKSPQADPNPTSSSHNNSEQEASNNNNSFSLPPILSPAPTPKERIDPFIKKPFIKEPFIELPRLQI
>NC_008312.1|WP_011613438.1|6323890_6324538_+|hypothetical-protein
MFVVPIQKFNATSAPITIFTDSGQAFGNSKSSGISLRDVNGDKEFDAFVANFDNQPNKVWFNDSNFTFTDSKQTLGNFYSLGVSLGDVDGNNDLDTFVTNTRQPNKGWLNNLDPSPICNNTSANKVVNGSFEEPEIYICQLSKESIKGWNLVEGPYIELDSSKIVKPYDGSQVLDLDSINARTKISQKISTVPPKTYKLTFAYQATNNLQAEVEH
>NC_008312.1|WP_011613437.1|6321623_6322703_-|fructose-bisphosphate-aldolase-class-II
MAIVPMRLLLDHAAENGYGIPAYNVNNMEQIQSIMQAAEEADSPVILQASRGARKYAGENFLRHLILAAVETYPHLPIAMHQDHGNAPSTCYSAMRHGFTSVMMDGSLEADGKTPASFEYNVNVTSEVVKVAHSIGVSVEGELGCLGSLETGMGDKEDGHGAEGKLSHDQLLTDPDEAVQFVEQTQVDALAVAIGTSHGAYKFTRKPTGEILAISRIEEIHRRLPNTHLVMHGSSSVPEDLLAIINEYGGKIPETYGVPVEEIQKGIKSGVRKVNIDTDNRLAITAAIREAAAKDPSNFDPRHFLKPSIKYMKQVCLDRYQQFGTAGNASKIKVQTLDEFADRYARGELAATTKTAVAV
>NC_008312.1|WP_011613436.1|6319090_6321223_+|hypothetical-protein
MTSRDSGINNNPEASWHLKSKQLPMWVRRCGAWATEISLVLVSGTVPFWLGQLGNIGNKSVPLNPAVAKTKEVIANTFGIPLRNRYQKVTPLANLLWSTALLTPAVIISWQLFLLATTGQTLPKRWFEVRVVAALGNSPGWKKTLIREGLGKWGFPMGTAYLIWRMTGAFPSLGILFFLGGLTSCIDIYFVRFNKLGRTGHDKLGNTFVIDARSGQLDSNPFNLSDTNRKTSIATIVLSEKKSESFHLWSWMRKNPGVTWLIVTSVGIVSVLGTIFGTHVYIQNQANWREFKQQDNDMFLALINKLSLTSNEPQQRRVSVLALGSTQDPRAIPLLVDLLAQEKEPSILDGIQQSLVSAGPTVLPELRRLNQALKNDLESLSYGSNTKEQVLVSLRIRATQKAIAKILKVYSGSLSLRDINLSGVDLGQITSTPASFTLILENTDLSGIKLRSAILNQASFKNSRFYGPGKDNRIGTFDDSIADLSGANLIEVNLTGAVLGPVIMKRADLFRATLSKAIMPGSTITQANFSSAKLIETNLHQANLTEATFTGADLGSADLSKANLYRANLSKVKAEGTTFQLSDLRESNWQGANLSGANFSRANLKKADLSLALLTNANFRNAQLQNANLRNTDISLADLRGANLSGTDFKGAKFAAPKPNQTDQFLASPIDTFKSDHLRGVNFNSAKNLSPNQINYICKQGGIHEKCGGN
>NC_008312.1|WP_011613447.1|6338711_6339935_+|glycine-betaine/L-proline-ABC-transporter-ATP-binding-protein
MNDKIINTNPLKSKIIIQNLIKIYGKKHRAALKLFREGKTRDDILQSTGNVLGLADVSIDIGTGELFVVMGLSGSGKSTLVRCINRLVDPTSGHIYIDGEDIAHADEKRMRDIRLNKVSMVFQRFGLFPHKTVAENVEYGLKVRGVSTTHRRQKALETLEVVGLEKWANYQPTSLSGGMQQRVGLARALATDADILLMDEAFSALDPLTRGEMQDELLRLQKELHKTIVFISHDMQEGLKLGDRIAVMKDGAIVQLGTPEELVTNPKNDYIKAFTEEVNSAQVITVGSIISKRTSLIIGQNSVSYGLEEMLKDNLQLLYVVDEYNKPIGLLKREGLQEFIKQGEEDFRAIMETDFPIVNSSTPLEDIFYLYKQGFPLAVVNDKKEFQGMVEAVDVLTSLGKPNKNYG
>NC_008312.1|WP_044137859.1|6340308_6342288_+|glycine-betaine/L-proline-ABC-transporter-substrate-binding-protein-ProX
MNYLSYYLITETQGGLNNLLNPFESYTLPLEEWVNNLVDFLVDNFRFIFQAISLPISGTLRIVELTFLAIPPLIFLIITGLLVWQLAGRKIAIYSFISLCIIGFCGAWEQSMVSLSLILTAVIFCMLIGIPLGIACALSDRFNKILRPLLDGMQTLPTFVYLVPVVMLFGIGEVSGIIATFVFAVPPLIRLTNLGIRQVSPEAVEAALAFGSTRQQVLLEVQIPLALPTILAGTNQAILLALSMSVVTSMIGVEGLGQMVLQGLGRLNVGLAAIGGLGIVLIAIMLDRITQGVSQGNIQSWQDRGPIGWWRSRKFFKHHKTTLGISILLALLVGVTGWQLMSQKNIKSTEHLLPGEGVVVRPTSGLETYGIFTTEIVNIGLEKLGYEIRGEKQLNVPAMHLAVSNGDLDFAGTHWEASHQEFFDNNGGEEKLERLGTLISNSTMGYQIDKKTADKYNITNISQLKEPKIAKLFDSDGDGKANLIGCTAGWSCERVINHHLEVYGLEDTVEQIQGNYSSLLADILVRYRQGKPILFFAWKPHWFSSILREGENVEWLSVPFTSLVGTMENFTEKDTLFNDKNIGFPIDNVRILANKKFLKANPVAKRLFEQIEIPLEDVSIEQEKVKNGENKPIDIRHHAEEWIVNHQGLFDSWLEIAKS
>NC_008312.1|WP_011613449.1|6342796_6343378_-|Chromophore-lyase-CpcS/CpeS-4
MKLKPPMTMMDFFLKSEGTWFSQRTVHHFDSAQDESGKSNILVKVLTKDDPKVIKVCEQQKVNPALAKGGASFNWQDNLDHGEPNPNYSAILVDIPDSQTGRTGKFLRNRGYIESIPVVSRYHFTNDGVLTIDTEYEKNQGQERCWFLTDDFRVRINTVRMMNGVNLMAYCSERRCITRKQLEEIVQKNAARS
>NC_008312.1|WP_011613450.1|6343753_6344590_+|pentapeptide-repeat-containing-protein
MQFQSATEIIQAYQQDKNLIASNLEGIDISEIELYEVNLSKSNLRQAKLHNTILIGANLIEADLSGVNLKGADLRGANLQGANLNGADLTNTYLNRAELQNANFTNANLEGAKLQVAYYDSYTVWPEGFPYKKSGAVGPGANLSGAFLNTADLKGADLRGANLRGSYLSGADLRGANLQGAALSGANMKGAFLIGANLRDALLNAVELEGADLRAADLTGASFNNVISIAGVDFTLAQGLSDDVRGMLCAYPGKDLGTWNSFTRTNTQSSLLSHLTDL
>NC_008312.1|WP_011613451.1|6344999_6345869_-|HIT-domain-containing-protein
MFTNKQPNQYTHLTAIDRKFISFPTQVILKQNLLVGKILDFGCGLGKDVKLLQKKGFDIIGYDPYYFPEYPQGKFDTILCFYVLNVLFEQPQIEVLMQISQLLNSEGKAYYAVRRGLKGEGFREHYIHKKPTYQCLVNLPFKSIYTDELREIYEYTHYNQQKNSENKCLFCNPRKNLQLITESAKAYAILDGYPVTKGHTLIIPKLHQENYFELPINDQLECWLMVNQVQKILQEKYQPDGFNIGINVNHAGGQKMMHTNIHVIPRYQKNELGTKGGMRSVVPKRRGKV
>NC_008312.1|WP_011613452.1|6348238_6348964_+|nitrogenase
MTNILKSRLNKEQTTAWLRGLMTIAYADGKLDATEKDLFDHFSHDEFASEIEISELQTISPDELAKIFRYDSSIAENFMRTAVMVALADGVYSSIEDEVLHKYCEALGLKVKALEALRKNLEQAKEEAENYDLKGWLEGTEDTNNSVIAHDPEHDRTILAPIKDWLDNWEINDSKVAHMVCKMIPSECPFERDVVIFGKKVAHIPAMCKLNPVYDQLVGLRFRALSYLADECKEDISKYYQ
>NC_008312.1|WP_011613453.1|6349314_6350373_+|GTPase-ObgE
MQFIDQAEIQVEAGKGGDGMVAFRREKFVPAGGPAGGNGGRGGSVVLVAVANLQTLLDFKFQRVFKAENGKRGGPKNMTGAGGSDRLIEVPPGTMIYDRETEELLGDLVKPGQTCCVAQGGKGGLGNKHFLSNSNRAPEYALPGLDGEVRMLRLELKLLAEVGIIGLPNAGKSTLIAALSAARPKIADYPFTTLVPNLGVVRKPTGDGTVFADIPGLIEGASAGLGLGHEFLRHIERTRLLLHLVDITDVDPVENFETIQNELEVYGRSLEDKRQVLALNKVDAVDVKGAEIQELVNRFREISGGKVFLISAVAGIGLEELMQEIWGLLEMEEEVKSSELTPTPPLVSREES
>NC_008312.1|WP_081432567.1|6350461_6350971_-|hypothetical-protein
MIELMITVSMIGALAAIAAPGWSALINNQRLRASNNRAYQIIKTAQTKAIQHKTTWQASFQQEQGKTIKWAVHQATVEPEKANWENLNSFVQVDDETTLYKYPSSKYPSSNIWRVQFNHKGHVNGQLGRLTLSLQSGGKAKRCVLVSTLLGKMRISKDQPKPKDEKYCY
>NC_008312.1|WP_011613455.1|6351648_6352359_-|type-II-secretion-system-protein
MKPLNLFKTLLRNQPKTSTTGFTIIELIFVVLIIGILSTIALPGWNAFINRQRTRTVNNGVLQALRAAQSDAKSTKVKKRLQFRYNDEKDPDTNKPYNDPPRFVIYDPPGDDEDPPSETYPKNDADGSDGFLWNSLRANGEIKPGMVKLSVKECETKDDDGNCKAYKDDEDGVIQFDNLGAVEVDDQELPQELPFAVSVSTAKEDAFKRCVIIETILGSMRIEEGEFNSSKGEGCP
>NC_008312.1|WP_011613456.1|6352421_6353438_-|type-II-secretion-system-protein
MYNLQKLLIKALSNSKLQKASNLTSGFTMTELLVATAVASIIIVPILTFAVDMLNRDVGEQAKANSEQELQTAISYIAQDMSQAFYVYEPDYVGEPGKTPPIPSYDDFIKQLPHSEDEDKDPILVFWKRKFIEHSIPIDDKDTSINCPADENKCDDGFVQSLVIYYLIEEQDKNSIWCQPSGSSCPKRIARFEIQDGVKDYWGNYFCGTDGRSEECSGSKKKFKRDLGYTSYDNSNPTGWTKKEGEDYSNSPVVLVNYIEDFTLDSASDYTKDSEIKQTELAKGKTLARVTILGNAMRRRRDGFSCIEDNSTTPPTYKKSPYCPKATAQVGPRSGFGE

Crispr_ID: NC_008312_42

• CRISPR_ID: NC_008312_42
• CRISPR_location: 6636390-6636481
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NC_008312_42

Consensus_repeat	Method
AAATGAATCAATATTCTAGTTCT	CRISPRCasFinder

spacers of NC_008312_42

>42.1|6636413|46|NC_008312|CRISPRCasFinder
AATGAAAATCCTTTAATATACTTTTATGGCTATAAAGTAATAATTG

CRISPR arrays and Neighbor proteins around NC_008312_42

CRISPR arrays

The CRISPR arrays of NC_008312_42

>merge|NC_008312|42|6636390-6636481|CRISPRCasFinder
AAATGAATCAATATTCTAGTTCTAATGAAAATCCTTTAATATACTTTTATGGCTATAAAGTAATAATTGAAATGAATCAATATTCTAGTTCT

>NC_008312|42|33|6636390-6636481|CRISPRCasFinder
AAATGAATCAATATTCTAGTTCT	AATGAAAATCCTTTAATATACTTTTATGGCTATAAAGTAATAATTG
AAATGAATCAATATTCTAGTTCT

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_008312.1|WP_011613619.1|6619683_6621075_-|histidine-kinase	unknown	unknown	gnl|CDD|226701
NC_008312.1|WP_155994723.1|6623996_6624083_+|hypothetical-protein	unknown	unknown	gnl|CDD|379094
NC_008312.1|WP_011613631.1|6644782_6645853_-|trypsin-like-peptidase-domain-containing-protein	unknown	unknown	gnl|CDD|379142
NC_008312.1|WP_011613629.1|6641687_6643400_-|hypothetical-protein	unknown	unknown	unknown
NC_008312.1|WP_044136974.1|6626716_6630622_+|hypothetical-protein	unknown	unknown	gnl|CDD|239804
NC_008312.1|WP_155994545.1|6648830_6648989_-|hypothetical-protein	unknown	unknown	unknown
NC_008312.1|WP_011613622.1|6624978_6625515_+|hypothetical-protein	unknown	unknown	gnl|CDD|188247
NC_008312.1|WP_011613632.1|6646718_6648005_-|Glu/Leu/Phe/Val-dehydrogenase	unknown	unknown	gnl|CDD|223411
NC_008312.1|WP_011610086.1|6615912_6616950_+|IS630-family-transposase	unknown	unknown	gnl|CDD|315923
NC_008312.1|WP_155994539.1|6615281_6615647_+|transposase	unknown	unknown	gnl|CDD|376573
NC_008312.1|WP_011613621.1|6623421_6623607_-|hypothetical-protein	unknown	unknown	unknown
NC_008312.1|WP_155994543.1|6619053_6619215_+|hypothetical-protein	unknown	unknown	unknown
NC_008312.1|WP_011613634.1|6650852_6652016_-|ferrochelatase	unknown	unknown	gnl|CDD|178068
NC_008312.1|WP_011613620.1|6621693_6623022_+|DUF3754-domain-containing-protein	unknown	unknown	gnl|CDD|372201
NC_008312.1|WP_011613636.1|6653982_6655119_+|KR-domain-containing-protein	unknown	unknown	gnl|CDD|224662
NC_008312.1|WP_011613635.1|6652209_6652848_+|class-I-SAM-dependent-methyltransferase	unknown	unknown	gnl|CDD|379312
NC_008312.1|WP_011613630.1|6644324_6644747_-|hypothetical-protein	unknown	unknown	unknown
NC_008312.1|WP_011613628.1|6640563_6641658_-|AAA-family-ATPase	unknown	unknown	gnl|CDD|223786
NC_008312.1|WP_011613633.1|6650223_6650817_+|DUF4126-domain-containing-protein	unknown	unknown	gnl|CDD|379253
NC_008312.1|WP_155994541.1|6616967_6617474_-|transposase	unknown	unknown	gnl|CDD|372577

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_008312.1|WP_011613619.1|6619683_6621075_-|histidine-kinase	gnl|CDD|226701	COG4250, COG4250, Predicted sensor protein/domain [Signal transduction mechanisms].	8.86709e-53
NC_008312.1|WP_011613632.1|6646718_6648005_-|Glu/Leu/Phe/Val-dehydrogenase	gnl|CDD|223411	COG0334, GdhA, Glutamate dehydrogenase/leucine dehydrogenase [Amino acid transport and metabolism].	0
NC_008312.1|WP_011613636.1|6653982_6655119_+|KR-domain-containing-protein	gnl|CDD|224662	COG1748, LYS9, Saccharopine dehydrogenase and related proteins [Amino acid transport and metabolism].	3.53482e-71
NC_008312.1|WP_044136974.1|6626716_6630622_+|hypothetical-protein	gnl|CDD|239804	cd04277, ZnMc_serralysin_like, Zinc-dependent metalloprotease, serralysin_like subfamily. Serralysins and related proteases are important virulence factors in pathogenic bacteria. They may be secreted into the medium via a mechanism found in gram-negative bacteria, that does not require n-terminal signal sequences which are cleaved after the transmembrane translocation. A calcium-binding domain c-terminal to the metalloprotease domain, which contains multiple tandem repeats of a nine-residue motif including the pattern GGxGxD, and which forms a parallel beta roll may be involved in the translocation mechanism and/or substrate binding. Serralysin family members may have a broad spectrum of substrates each, including host immunoglobulins, complement proteins, cell matrix and cytoskeletal proteins, as well as antimicrobial peptides.	1.81454e-37
NC_008312.1|WP_011613622.1|6624978_6625515_+|hypothetical-protein	gnl|CDD|188247	TIGR02795, Uncharacterized_protein_in_oprL_3'region, tol-pal system protein YbgF. Members of this protein family are the product of one of seven genes regularly clustered in operons to encode the proteins of the tol-pal system, which is critical for maintaining the integrity of the bacterial outer membrane. The gene for this periplasmic protein has been designated orf2 and ybgF. All members of the seed alignment were from unique tol-pal gene regions from completed bacterial genomes. The architecture of this protein is a signal sequence, a low-complexity region usually rich in Asn and Gln, a well-conserved region with tandem repeats that resemble the tetratricopeptide (TPR) repeat, involved in protein-protein interaction.	4.83331e-05
NC_008312.1|WP_011613620.1|6621693_6623022_+|DUF3754-domain-containing-protein	gnl|CDD|372201	pfam12576, DUF3754, Protein of unknown function (DUF3754). This domain family is found in bacteria, archaea and eukaryotes, and is typically between 135 and 166 amino acids in length. There is a single completely conserved residue P that may be functionally important.	1.60962e-45
NC_008312.1|WP_011610086.1|6615912_6616950_+|IS630-family-transposase	gnl|CDD|315923	pfam13358, DDE_3, DDE superfamily endonuclease. This family of proteins are related to pfam00665 and are probably endonucleases of the DDE superfamily. Transposase proteins are necessary for efficient DNA transposition. This domain is a member of the DDE superfamily, which contain three carboxylate residues that are believed to be responsible for coordinating metal ions needed for catalysis. The catalytic activity of this enzyme involves DNA cleavage at a specific site followed by a strand transfer reaction.	1.1025e-33
NC_008312.1|WP_155994539.1|6615281_6615647_+|transposase	gnl|CDD|376573	pfam01609, DDE_Tnp_1, Transposase DDE domain. Transposase proteins are necessary for efficient DNA transposition. This domain is a member of the DDE superfamily, which contain three carboxylate residues that are believed to be responsible for coordinating metal ions needed for catalysis. The catalytic activity of this enzyme involves DNA cleavage at a specific site followed by a strand transfer reaction. This family contains transposases for IS4, IS421, IS5377, IS427, IS402, IS1355, IS5, which was original isolated in bacteriophage lambda.	0.000705156
NC_008312.1|WP_011613631.1|6644782_6645853_-|trypsin-like-peptidase-domain-containing-protein	gnl|CDD|379142	pfam13365, Trypsin_2, Trypsin-like peptidase domain. This family includes trypsin-like peptidase domains.	3.28252e-15
NC_008312.1|WP_011613634.1|6650852_6652016_-|ferrochelatase	gnl|CDD|178068	PLN02449, PLN02449, ferrochelatase.	0
NC_008312.1|WP_155994723.1|6623996_6624083_+|hypothetical-protein	gnl|CDD|379094	pfam13267, DUF4058, Protein of unknown function (DUF4058). This family of proteins is functionally uncharacterized. This family of proteins is found in bacteria. Proteins in this family are typically between 244 and 264 amino acids in length.	0.000128577
NC_008312.1|WP_011613635.1|6652209_6652848_+|class-I-SAM-dependent-methyltransferase	gnl|CDD|379312	pfam13649, Methyltransf_25, Methyltransferase domain. This family appears to be a methyltransferase domain.	1.03271e-28
NC_008312.1|WP_011613628.1|6640563_6641658_-|AAA-family-ATPase	gnl|CDD|223786	COG0714, COG0714, MoxR-like ATPases [General function prediction only].	1.12024e-14
NC_008312.1|WP_011613633.1|6650223_6650817_+|DUF4126-domain-containing-protein	gnl|CDD|379253	pfam13548, DUF4126, Domain of unknown function (DUF4126).	9.11962e-35
NC_008312.1|WP_155994541.1|6616967_6617474_-|transposase	gnl|CDD|372577	pfam13359, DDE_Tnp_4, DDE superfamily endonuclease. This family of proteins are related to pfam00665 and are probably endonucleases of the DDE superfamily. Transposase proteins are necessary for efficient DNA transposition. This domain is a member of the DDE superfamily, which contain three carboxylate residues that are believed to be responsible for coordinating metal ions needed for catalysis. The catalytic activity of this enzyme involves DNA cleavage at a specific site followed by a strand transfer reaction.	1.01027e-38

Protein sequences

>NC_008312.1|WP_044136974.1|6626716_6630622_+|hypothetical-protein
MLNNDFFYREAIMNNRYNKPDQVDNSRKKAYQVGALQNDEKFEDFVGKSDKRDFYQFKVEEKTDVDIKLDDLSGNANLYLLNNKGKLIEKSTKGGKNAEDIERTLNPGAYYVKVQSNEEDANYTLSLDVGSGSQQEDKVGNNRKKAYKFGALKNDEKFEDFVGKSDQRDFYQFKVEEKTDVDIKLGGLSGNADLYLLNNKGKLIEKSTKGGDSLENIERTLNPGAYYVKVQSNEEDADYTLSLGVGSGSQQEDKVGNNRKKAYKFGALKNNEQFEEFVGKSDKRDFYRFKVEEKTDVDIELGGLGGNADLYLLNNKGRLIEKSTKGLNKVEDIERTLNPGTYYVKVQSNDEDAKYTLSLDVGSGSKNLEKYEFTYYYSGSQDNEFQDYYSGYFYAPKGTYEVDSYYDFNEEKNEASANGKYYISSSSKAGAKAKDGEVYLESYYDLETKKEYVPYYASEDLPSGASGMGSEEDFIDFEKDEDVIELKQEGFFGADYSLANIVKEAQTSKSGDYQIDALLSPYKWGTNTITYSFYDNDSGPYYGAERDVGEVSDKVQEDIRHILENIYEPLSDLDFVEVADTSNSYGLIRIMKSSNPNYAYAYYPYADDYNAGNLLDLAGDVHFNVYYDGNGDHNNFQGGPGTHGYMTLIHELGHAVGLKHPHEDGDTLPENEDNTSNTVMSYNFTYTADNLRSYDVNALQYIYGFETPEDSVTVKSPNGGDTLKLGKSYTITWDDNFSENVKLELYKGGSFDSIITNSTASDGSYGWTLPTSMAIGSDYKVKITSVSDAGVSDLSDSNFTIERDGVITVKSPNGGDVINTGDTYDVTWDDNISENVRIYLYQGNRYKQMISNSTPSDGSYSWTVPTSLTAGDNYEVAIQSVEKGSLYDYSDSSFTIEPDGVITVKSPNGGDVINTGDTYNITWDDNISENVRIDLYQDNRYKQMISNSTSSDGSFRWRVPTNLATGDNYQVAIQSVEKDRIFDFSDSNFTIEPDGVITVKSPNGGDVINTGDTYNITWDDNISENVRIYLFQGNRYKQMISNSTPSDGSYSWTVPTSLTAGDNYEVAIQSVEKGSIYDYSDSSFTIEPDDFITVMSPNGGDILNTGDTYNITWDDNIGENVRIYLFQGNRYKQMISNSTPSDGSYSWKVPTNLTTGGNYQVAIQSVEKGSLYDFSNSNFSIKTEDVSSDKYYFTYYYNVGDSYSGFLYEKSGTYSSDDILSVTSGFYQIDDIESGVGNKDDIGDVYISSYYDSNYTGNTYQPLLSRYGWRSGGNGLGSERDYLGFPSYQSFDSNNEFNGLI
>NC_008312.1|WP_011613622.1|6624978_6625515_+|hypothetical-protein
MNLENLELFEAEFNAGKQAFESGQYSKSLQHLETALKNVNPNSRLGGETQIWLVTVYQAVGKFQEATTLCKKLIHHSYLQTRQQAKRILAILEAPVLRTRPEWVTKIPDLGAISESDAQDRGGSGLVSQVKSPSPQPKTEISQLEVVDPSKVNTQDNQFVLVALVLIILTLTGLVWLS
>NC_008312.1|WP_155994723.1|6623996_6624083_+|hypothetical-protein
MNPYLENPKFWPLVYKYLIIGTIKYLFR
>NC_008312.1|WP_011613621.1|6623421_6623607_-|hypothetical-protein
MVESNLWIPIGVVVVGFVAAVTIGSIAWYNSKRPPGWENTQRPDYIPQFSDKDKNTEANSE
>NC_008312.1|WP_011613620.1|6621693_6623022_+|DUF3754-domain-containing-protein
MAVYQDREAFIPYSRRDLIELCIRDGKLPDASLQKFRDFCSILVAYYHFKLHKKLEIFKESYAPFNPDIDTKSIVDCSYSQLIIMKNKVVENFQEILGQSNYYPISKASLERAFQKKSLIELKTDINFDDFEEIICYCRGDIYKTIKVKKFFQKIEKKIDIFERVALLIKFQSQKNVDSSEKLMEESNLIPSKIYLSLYKNIPKDDIEFLFPNLKISMTLKDRLMLAVPAIGAAVPLALKILPQFLLIISVIIFLTFGPSHIERFNLRVSPEDIKNMTGILIATLSLLVTLGGFCFKQYTQYKNKQIKFQKQVTETLFFQIIANNASVFQCLVDDAEEEECKEIILVYYHLLTSNTSLTPEQLDNKIEVWMEKKFDRKIDFDIDGPLNNLTQIKGKIISDSKNEDQIPDVSLLSYDENGCCQVLSMDNGKKLIDYIWDNLYY
>NC_008312.1|WP_011613619.1|6619683_6621075_-|histidine-kinase
MDSKATLNQLKKRSPEGKLPGSYGVYFKNTLVALCHALEDHILQVSSQHPEAKPLVLATFQQGKWYLQEADRYQELAQCSRHIMIAAVADSGLSKHPTSKLDNVSLINLETTDSIVNEWNLIILAPSYRAMVLCHELSEDEYLPNCKPTVDIERKFYGLWTFDETLVAKAAEILVERCRPYNPELADTIQKQHQEIIETKGIAPTDMSGVVSRIVSYLQKTQEQMIAINRQTRELWELEDQALRVTHNLNTNKLQAFIRMAQKVDEQDQTNPLASLQVAALCETLGNLLDLPTPKLRRLRLAGLLFRVGLVSAPKEVFSKTPDELDPKSLNFWQKQNLFGSQLLGAMPELVPITKIIAHYLEYWDGSGKPDGLKEEEIPIESRILGLVSYFQELTIPRGKRPALSLGESLEKCSARKGTYFDPTLVETLNNVVRLTEMGLMELPKRPSQLPNVWLEDVARLIE
>NC_008312.1|WP_155994543.1|6619053_6619215_+|hypothetical-protein
MVNPKVIKYTSRTASLQGVICDRNIHATKPFGFATFQVLEERQVYYIRVVMFD
>NC_008312.1|WP_155994541.1|6616967_6617474_-|transposase
MLTEQELIVDSTEKSIYRPYSDDKQKKYYSGKKKNHTLKNQIITTEKGTEIVDVNVGKRGPESDVNLLIKQLSKFDKEQKFQGDKGYQGAERTITPKKKPRKQEMSPKMKENNLKLAKKRIFVEHVIRLLKIFGIVRERFRLKEYNYEKVILTICGLVRLRIGALILA
>NC_008312.1|WP_011610086.1|6615912_6616950_+|IS630-family-transposase
MNIIDKLNDFINQTKESKEIKRALAVKMTLSGKSYHEVKELLNVSHSFISEWKNQALFHGVESLRLQYQGRQGYLKTVEKEKTIEWLRAQDYLRLSDLKNYLQEQYDVVFESNQSYYNLFKEAGISWKKTQKKNPAKNDELVEVKRKEIEEFLAKWQPEIETGKLTVFMIDECHLLWGDILGYAWGKTDERIEIAIKNEKERQTYYGALDYKTKEFLVQEYESGNTKNTIEFIKYLQKQRPGNKLAIFWDGATYHNSQEFREYLMTINQYLSEEELLINCTRFAPNAPEQNPVEDIWLQTKNFSITFYHLCSSFKVVKWLFKFFADGQIFNFPKLFQYEILPQPT
>NC_008312.1|WP_155994539.1|6615281_6615647_+|transposase
MVTAVVTTNDVSDDQVFSDLLDGVEGEIAQVSGDGADDKYKCYETAHQRGIKTTIPPRKNAVIRQHGNCKALPAPRDENLRGIRQIGRQKWKHESGYHRRSLSGTTMFRFKVLFGGKLRRR
>NC_008312.1|WP_011613628.1|6640563_6641658_-|AAA-family-ATPase
MSHWHLFQGNGIKEKGVEKKLLNIEPPPWRKFGETTDIKVNEKGIDSRWLELRKLAKQQKKGLERGKNFRLPQQQKEAKDVINSVNAAIYLRRPLLITGKPGSGKTSLAYAIAYELGLGTVLSWSITARSALQDGLYRYDAIARLQDAQLKKEQHIGEYITLGALGTAFLPSQFPRVLLIDEVDKSDINLPNDLLNIFEEGEFIIPELMRRSKSRKSAESSQEFSQESPQQFTVWTQDEDKVTLKTGKVKCAAFPIIVMTSNGERDFPPAFKRRCLRVTMPDPKEEALKSIVQAHFGDELYNQNQDYIGELIKEFLPKQEEGEAFDRATDQLLNTIHILTQSNSPQDDNNIESLKEILFKNLSQ
>NC_008312.1|WP_011613629.1|6641687_6643400_-|hypothetical-protein
MNLSKSERKYLFKALEDGYRSYDQLRIMFRLNLEKNLEEIVKRDPLDNVILALIEWAESQNKLLDLVWGANDQNPHNLPIKNITYQLFYITEKQWEKLYKLLSQIHPTYLDLAFQETFQPKEIVEVDPRLINLKSLEAEETQDTLKDNLIKKREQSSREIPVVLEFVDYLSRMPYEQIDISLQTILSNPNYLPTKSTIPNEFKTWVSEVSHQLNIQLETQKQKESRSNLKIWLSKFTARLQKKDTLLKTQEKNKNLSKFLPTEKIQPYLLISLEDAGSDLLLQGELVLEKDHSKKILKQKPIYIQEQTQAVRCAKNFKKIGNCLKKFIQKSYWKLQHYRSRNSNIRFEPSIIIELFLPIKYFLKPMEAIPLPIKNSTLFAGESRKLCCEHPLTFRILERFETYQNNREYLLRLENNWQEVNDFFISQSPLTSEIIENKFEHHSRYEKWKILEARLRDNQKIGINIISPLKNIQEIKEIMKAIIIAGIPIALWSINLKYTPEKLKTNFLQILTLQDIKSLTSLLNSIKKLREEAYIDDNNEEKLGYGLGFLCDNPYRILSRFEEDDAYTFG
>NC_008312.1|WP_011613630.1|6644324_6644747_-|hypothetical-protein
MNRSIIETELQASETKSDIDNYFDKIVKYIPSEIVGVWITIKTMVEGNNNVPENSILWGIFIFCLFLTFAYICLLPVSSKKKPTIKQGIISVGAFIVWAIAIGGKPFISISWYQPIYGSILMVLYTVVIPLIPLEKRKLS
>NC_008312.1|WP_011613631.1|6644782_6645853_-|trypsin-like-peptidase-domain-containing-protein
MTLSGFETEELFEALLDSYRDYGKLQRMVRFKLEENLERFAGKGDLETVVFNLIDSAEARGKLKSLIIGAYEQNPDNQKLKKFFHTISKDFQKRAILDYDLTPIRDFGPNIDWHGKTDQIELQGLFKKQPDWYDVGFLQKIIEQAKSVCRLDVPNLNITATGVLIASKYVLTNYHVLKQNNNNNLELNAKNIRISFGCFSLNNSRESTSKSFLLDSEKPIISSSPVGELDYILLQLEKTFSQALDSEDTKIKPAKWQPHIFLSEADSINILQHPNGESMKLSITCDGITGVYPHSGLVQYINRTAGGSSGSPCFNENGELVALHHAQRSKYFGTIREGILFSSIHHDLEQKSIQLN
>NC_008312.1|WP_011613632.1|6646718_6648005_-|Glu/Leu/Phe/Val-dehydrogenase
MSDSLFDDASRRLERALQYVSLSEDTKERLKYPKATLIVSIPVRMDDGSLRVFQGYRVRYDDTRGPTKGGIRYHPNVSIDEVKSLAFWMTFKCAVVSLPFGGAKGGITVNPKELSRMELERLSRGYIDAIADFIGPDTDIPAPDMYTNPMIMGWMMDEYSIIRRQLSPAVITGKPVSIGGSLGRNTATAMGAFFAIETIMPKFEYTPEKTTVAIQGFGNAGAFLAELLCLHGYKVVAVSDSQGGIYSAQGLDIPSIRQYKEVNKQIQAVYCKDSVCNIVEHTVLTNEELLALDVDILIPAALENQITEENVKDIQAKFIFEAANGPTTSGADKILEDRGVYVFPDILINAGGVTVSYFEWVQNRSGLYWTLDEVNQKLKAKMVAETENIWQISQELSISMRTAAYVHGLDRLGQAINAKGTRAFYAKR
>NC_008312.1|WP_155994545.1|6648830_6648989_-|hypothetical-protein
MTLLKLAQIIRFKRTKTQQKQKNHIITNAFAIENKFSPEGKLDEAIASTQKA
>NC_008312.1|WP_011613633.1|6650223_6650817_+|DUF4126-domain-containing-protein
MLEVLAALSASAAAGIRIALPLLLIGLLQNDLWAKVPMLSKISPQIVVGILVSWSLFEIFASKHLLGQRVLNLVQIIFSPIVGTIMSMAIAEATHSKGWLIIVIGVVGGLLALVLQIVQVGWFFRWRGLPVWMLLSQDILCICLVIFALDAPQQGGLIALLLLWLAIHSYQDWYKLYQGKTKRGSSLQPQTHSSNFD
>NC_008312.1|WP_011613634.1|6650852_6652016_-|ferrochelatase
MSRVGILLLNLGGPEQLEDVRPFLFNLFSDPEIIRLPFPWLQKPLAWFISTMRFQKSQENYKEIGGGSPLRSITEEQALAIQQQLEQKGLLTQMYIGMRYWHPFTEEALTRIKREQVEKLVILPLYPQYSISTSGSSFRLLDKLWEKDSELKKIEYTVIPSWHQRPGYVQAMVELITQQLDQSPNPDQVHIFFSAHGVPVSYVEEAGDPYQAEIEECVDKIMKTLNCSNPHTLAYQSRVGPVEWLKPYTEDAIEELAAGGVKDLLVVPISFVSEHIETLQEIDIEYRELAEEAGISNFYRVPALNTHPVFINDLADLVMEALDAPSRDFSDAIQMKKIIKMYPQERWQWGLTTTAEVWNGRLAMVGFMALLLELITGYGPLHFAGLL
>NC_008312.1|WP_011613635.1|6652209_6652848_+|class-I-SAM-dependent-methyltransferase
MATILRDWSYRYQWLYDGISRLASLSVGGETRFRQLALEGLIIEENTQILDLCCGSGQGTNFLAKYSQSVTGLDASPLSINRAKKNVPSAKYVEGFAEDMPFSSNQFDLVHTSAALHEMNYEQLRQIIQEVYRVLKPSGIFTFVDFHSPTNPLFWPGFAMFLWLFETETSWKFINTNILELLTTIGFNLVDTKLPLPILYAGGSLQVIQVQK
>NC_008312.1|WP_011613636.1|6653982_6655119_+|KR-domain-containing-protein
MTNQVLIIGGYGRIGSSVARDLATYTNSEITITGRKPEANIQEIPISGVKYLALDLADKERVKNIINSYNKSSKNLVINCAGPFHYRDANVLKNCIKAGINYIDISDYRGFTCKALEYSEAAKKAGVTAIINTGIFPGISNSLSRESIEKLDEPEEIHLSYVVGGSGGAGVTVMRTTFLGLQSHFDAWINGKWQSVKPYSDRQVIDFPAPYGKIGVYWFDMPESLTLATSFPVNTVTTKFGSFPDFYNHLTWMTAHLFPVSWLNNLGVIEFLSQVSYKMTEFTDKYSGTGVVIQAKVIGKKSGKKADFSSSIMHKDTATVTGIGAGSIAELILSGKLNKPGVSSVENSLSTELFEQVMQSRGFVKNYGDNCVIYQPLN

Crispr_ID: NC_008312_43

• CRISPR_ID: NC_008312_43
• CRISPR_location: 6697921-6698031
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers
• Cas_protein_info: WYL

Consensus repeat of NC_008312_43

Consensus_repeat	Method
GCGGAAGGCTCAGGAACATGCTTTGTT	CRISPRCasFinder

spacers of NC_008312_43

>43.1|6697948|57|NC_008312|CRISPRCasFinder
AGTTTATTTGTTGGTTGATCAGAAAAAGTATTTTCCGGAATAAACACGGCAGGATCA

CRISPR arrays and Neighbor proteins around NC_008312_43

CRISPR arrays

The CRISPR arrays of NC_008312_43

>merge|NC_008312|43|6697921-6698031|CRISPRCasFinder
GCGGAAGGCTCAGGAACATGCTTTGTTAGTTTATTTGTTGGTTGATCAGAAAAAGTATTTTCCGGAATAAACACGGCAGGATCAGCGGAAGGCTCAGGAACATACTTTGTT

>NC_008312|43|34|6697921-6698031|CRISPRCasFinder
GCGGAAGGCTCAGGAACATGCTTTGTT	AGTTTATTTGTTGGTTGATCAGAAAAAGTATTTTCCGGAATAAACACGGCAGGATCA
GCGGAAGGCTCAGGAACATACTTTGTT

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_008312.1|WP_081432499.1|6691170_6691452_+|pentapeptide-repeat-containing-protein	unknown	unknown	gnl|CDD|224276
NC_008312.1|WP_011613666.1|6703128_6704442_+|threonine-synthase	unknown	unknown	gnl|CDD|236065
NC_008312.1|WP_155994551.1|6699115_6699298_+|hypothetical-protein	unknown	unknown	unknown
NC_008312.1|WP_011613661.1|6695989_6697543_+|C-3',4'-desaturase-CrtD	unknown	unknown	gnl|CDD|274272
NC_008312.1|WP_044136979.1|6685741_6687259_+|SagB/ThcOx-family-dehydrogenase	unknown	unknown	gnl|CDD|380318
NC_008312.1|WP_011613665.1|6702575_6702854_+|MoaD/ThiS-family-protein	unknown	unknown	gnl|CDD|340452
NC_008312.1|WP_011613667.1|6704734_6705010_+|MoaD/ThiS-family-protein	unknown	unknown	gnl|CDD|340594
NC_008312.1|WP_011613660.1|6693567_6694863_-|insulinase-family-protein	unknown	unknown	gnl|CDD|223685
NC_008312.1|WP_155994725.1|6692390_6692903_-|CAP-domain-containing-protein	unknown	unknown	gnl|CDD|349398
NC_008312.1|WP_011613671.1|6712498_6712870_-|hypothetical-protein	unknown	unknown	unknown
NC_008312.1|WP_011613670.1|6710539_6711412_-|carboxylating-nicotinate-nucleotide-diphosphorylase	unknown	unknown	gnl|CDD|236017
NC_008312.1|WP_044137884.1|6683810_6684332_-|pentapeptide-repeat-containing-protein	unknown	unknown	gnl|CDD|224276
NC_008312.1|WP_011613652.1|6682092_6682311_+|hypothetical-protein	unknown	unknown	unknown
NC_008312.1|WP_011613656.1|6688072_6690226_-|WYL-domain-containing-protein	WYL	pfam13280_WYL_CAS-I:CAS-III	gnl|CDD|379324
NC_008312.1|WP_011613653.1|6682447_6683443_-|ketol-acid-reductoisomerase	unknown	unknown	gnl|CDD|235491
NC_008312.1|WP_011613658.1|6691473_6691836_+|hypothetical-protein	unknown	unknown	unknown
NC_008312.1|WP_011613664.1|6699592_6700990_-|Rieske-2Fe-2S-domain-containing-protein	unknown	unknown	gnl|CDD|215283
NC_008312.1|WP_071820711.1|6701529_6701619_-|cytochrome-b6-f-complex-subunit-PetN	unknown	unknown	gnl|CDD|367633
NC_008312.1|WP_155994726.1|6707506_6708418_-|SUMF1/EgtB/PvdO-family-nonheme-iron-enzyme	unknown	unknown	gnl|CDD|224182
NC_008312.1|WP_011613668.1|6705408_6706437_+|peptidoglycan-binding-protein	unknown	unknown	gnl|CDD|379241

HMMScan for Signature genes

Protein	Cas_name	Cas_description	E-value	Identity	Coverage
NC_008312.1|WP_011613656.1|6688072_6690226_-|WYL-domain-containing-protein	WYL	pfam13280_WYL_CAS-I:CAS-III	6.6e-24	79.6	0.0

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_008312.1|WP_081432499.1|6691170_6691452_+|pentapeptide-repeat-containing-protein	gnl|CDD|224276	COG1357, COG1357, Pentapeptide repeats containing protein [Function unknown].	1.25184e-11
NC_008312.1|WP_011613666.1|6703128_6704442_+|threonine-synthase	gnl|CDD|236065	PRK07591, PRK07591, threonine synthase; Validated.	0
NC_008312.1|WP_011613668.1|6705408_6706437_+|peptidoglycan-binding-protein	gnl|CDD|379241	pfam13529, Peptidase_C39_2, Peptidase_C39 like family.	1.0016e-18
NC_008312.1|WP_011613661.1|6695989_6697543_+|C-3',4'-desaturase-CrtD	gnl|CDD|274272	TIGR02733, similar_to_to_phytoene_dehydrogenase, C-3',4' desaturase CrtD. Members of this family are slr1293, a carotenoid biosynthesis protein which was shown to be the C-3',4' desaturase (CrtD) of myxoxanthophyll biosynthesis in Synechocystis sp. strain PCC 6803, and close homologs (presumed to be functionally equivalent) from other cyanobacteria, where myxoxanthophyll biosynthesis is either known or expected. This enzyme can act on neurosporene and so presumably catalyzes the first step that is committed to myxoxanthophyll. [Biosynthesis of cofactors, prosthetic groups, and carriers, Other].	0
NC_008312.1|WP_011613653.1|6682447_6683443_-|ketol-acid-reductoisomerase	gnl|CDD|235491	PRK05479, PRK05479, ketol-acid reductoisomerase; Provisional.	0
NC_008312.1|WP_011613665.1|6702575_6702854_+|MoaD/ThiS-family-protein	gnl|CDD|340452	cd00754, Ubl_MoaD, ubiquitin-like (Ubl) domain found in molybdenum cofactor biosynthesis protein D (MoaD) and similar proteins. MoaD, also termed molybdopterin synthase sulfur carrier subunit, or MPT synthase subunit 1, or MPT synthase small subunit, or molybdopterin-converting factor small subunit, or molybdopterin-converting factor subunit 1, is a conserved small sulfur carrier protein that has beta-grasp ubiquitin-like (Ubl) fold involved in biosynthesis of the molybdenum cofactor (Moco), an essential cofactor of a diverse group of redox enzymes. MoaD is activated in an ATP-dependent manner by sulfurtransferases similar to the activation mechanism of ubiquitin-activating enzyme E1.	1.71898e-23
NC_008312.1|WP_011613667.1|6704734_6705010_+|MoaD/ThiS-family-protein	gnl|CDD|340594	cd17074, Ubl_CysO_like, ubiquitin-like (Ubl) domain found in Mycobacterium tuberculosis CysO and similar proteins. CysO, also termed 9.5 kDa culture filtrate antigen cfp10A, together with CysM (Cysteine synthase M), forms a protein complex CysM-CysO that represents a new cysteine biosynthetic pathway in Mycobacterium tuberculosis. The replacement of the acetyl group of O-acetylserine by CysO thiocarboxylate to generate a protein-bound cysteine is catalyzed by CysM in a pyridoxal 5?-phosphate (PLP)-dependent manner. The family also includes QbsE that functions as the sulfide donor for the biosynthesis of thioquinolobactin in Pseudomonas fluorescens. A JAMM motif protein QbsD catalyzes removal of the carboxy-terminal dipeptide from QbsE. Both CysO and QbsE are similar to prokaryotic sulfur carrier proteins such as ThiS and MoaD, containing the beta-grasp ubiquitin-like fold.	1.70889e-45
NC_008312.1|WP_011613660.1|6693567_6694863_-|insulinase-family-protein	gnl|CDD|223685	COG0612, PqqL, Predicted Zn-dependent peptidases [General function prediction only].	2.40645e-99
NC_008312.1|WP_155994725.1|6692390_6692903_-|CAP-domain-containing-protein	gnl|CDD|349398	cd05379, CAP_bacterial, Bacterial CAP (cysteine-rich secretory proteins, antigen 5, and pathogenesis-related 1 proteins) domain proteins. Little is known about bacterial and archaeal members of the CAP (cysteine-rich secretory proteins, antigen 5, and pathogenesis-related 1 proteins) domain family. The wider family of CAP domain containing proteins includes plant pathogenesis-related protein 1 (PR-1), cysteine-rich secretory proteins (CRISPs), and allergen 5 from vespid venom, among others. Studies of eukaryotic proteins show that CAP domains have several functions, including the binding of cholesterol, lipids and heparan sulfate. This group includes Borrelia burgdorferi outer surface protein BB0689, which does not bind to cholesterol, lipids, or heparan sulfate, and whose function is unknown.	6.02677e-32
NC_008312.1|WP_011613670.1|6710539_6711412_-|carboxylating-nicotinate-nucleotide-diphosphorylase	gnl|CDD|236017	PRK07428, PRK07428, carboxylating nicotinate-nucleotide diphosphorylase.	0
NC_008312.1|WP_044137884.1|6683810_6684332_-|pentapeptide-repeat-containing-protein	gnl|CDD|224276	COG1357, COG1357, Pentapeptide repeats containing protein [Function unknown].	1.24199e-22
NC_008312.1|WP_011613656.1|6688072_6690226_-|WYL-domain-containing-protein	gnl|CDD|379324	pfam13671, AAA_33, AAA domain. This family of domains contain only a P-loop motif, that is characteristic of the AAA superfamily. Many of the proteins in this family are just short fragments so there is no Walker B motif.	2.15227e-22
NC_008312.1|WP_044136979.1|6685741_6687259_+|SagB/ThcOx-family-dehydrogenase	gnl|CDD|380318	cd02142, McbC_SagB-like_oxidoreductase, oxidase similar to the microcin B17 processing protein McbC. This family is the oxidase domain of NRPS (non-ribosomal peptide synthetase) and other systems that modify polypeptides by cyclizing a thioester to form a ring. These include EpoB, part of the epothilone biosynthesis pathway; TubD, part of the tubulysin biosynthesis pathway, MtsD, part of the myxothiozol biosynthesis pathway; IndC, part of the indigoidine biosynthesis pathway and TfxB, part of the trifitoxin processing pathway. All are FMN-dependent and oxidize the product of the cyclization of thioesters in short polypeptides.	3.23999e-49
NC_008312.1|WP_011613664.1|6699592_6700990_-|Rieske-2Fe-2S-domain-containing-protein	gnl|CDD|215283	PLN02518, PLN02518, pheophorbide a oxygenase.	2.02518e-92
NC_008312.1|WP_071820711.1|6701529_6701619_-|cytochrome-b6-f-complex-subunit-PetN	gnl|CDD|367633	pfam03742, PetN, PetN. PetN is a small hydrophobic protein, crucial for cytochrome b6-f complex assembly and/or stability.	1.93988e-06
NC_008312.1|WP_155994726.1|6707506_6708418_-|SUMF1/EgtB/PvdO-family-nonheme-iron-enzyme	gnl|CDD|224182	COG1262, COG1262, Uncharacterized conserved protein [Function unknown].	6.72348e-79

Protein sequences

>NC_008312.1|WP_011613661.1|6695989_6697543_+|C-3',4'-desaturase-CrtD
MSSKNTRQKSKVVVCGAGIGGLTTAALLAHRGYEVQIFDQAIIPGGCASTFKRRGFTFDVGATQVAGLEPGGIHHRIFSELEIDIPNATNCDPACAVFLPGETEPINVWRDPEKWQEERQRQFPGSEPLWQLMTKLFEASWKFQGRDPVLPPRNIWDLWQLVKAVRPDTLITVPFTLMTVADALQLCGLNDNLRLKTFLDLQLKLYSQVGTEETALLYAATALAVSQAPQGLYHLEGSMQELSDRLVAALKRDGAKLFMGHTVENIHVDNGKANAVRIRNQKTGETWVETADHVVANVTVQNLVKLVANENQPHTLDSMAGYKRRVDKLPSPWGAFIVYLGVDESAIPTNCPPHLQFFYNYDGPIGENNSLFVSVSHPGDGRAPTGKATITASSFTDTQIWRHSQNYQELKQKYMEEAIAHLSGYFDLRPETIVYQEAATPRTFVKFTARDEGIVGGVGQRLANFGPFGIANRTPIQDLWLVGDSTHPGEGTAGVSYSALTVVRQIDAEEGFTGFFS
>NC_008312.1|WP_011613660.1|6693567_6694863_-|insulinase-family-protein
MTSTLVPPTLSYLNTPTVRQLPNGLTIIAEHLAVEAVNLNIWLNVGSALESESINGMAHFLEHMVFKGTPKLPSGEFERLVEQKGGLMNAATSQDYTYFYITTAPKDFAKLAPLQWEILLNPSIADDAFEQERLVVLEEIRRSDDSPSRRCYQKVIETAFEKLPYRRPVLGPPEIISQLQTQQMRDFHQSLYKPSSMTATVVGNLPVEELIDIVTDSFTEANNGKSTSETLLPPNINFTPESPFTKIVRHEVVDEALQQPRLIMFWRVPGLTELYETYALDVLATILGGGKTSHLVRDLREERGLVYSIGISNVSHRYQGLFYVSARLPEENLAEVEAAIAHHIYTIQQESVTDAEMQRIRTLVAKRFIFANETPSDRASLYSYYQSMVGDLGSAINYPQNIQAFESSDIQQAALKYLSVDAYGVAVFRPK
>NC_008312.1|WP_155994725.1|6692390_6692903_-|CAP-domain-containing-protein
MVIFLSSCNYQKSIQSFSEMQDNLYPKKNYISSTNLAASQNIKELEKNTFTLINQYRQSKNLPALQWNNDIVQQSRIHAQQMASGKTTFSHDGFKKRVEIISQKIPYKGAAENIASNQGYSDPAEAAVKGWIKSPGHHKNIVGDYNLTAIGIAQNSQGMYYFNQLFIKTR
>NC_008312.1|WP_011613658.1|6691473_6691836_+|hypothetical-protein
MFARETIFKDYKSAAYNLEASKAIENRLKNLILLIAISYAISSFQGKKIKNKGLQEYISRTNERGRKERRHNSFFVGLSRIYWAINDNFIWELVEHLMSLNPHKFLYYRREIKAMNTVVN
>NC_008312.1|WP_081432499.1|6691170_6691452_+|pentapeptide-repeat-containing-protein
MNPNLAKKNLDGINLSGVNLNKVNLREASLIKAQLHRTKMVGANLDSANLKGAHLSRANLKDAQASWADLRNTNMSNTVLHNANLTGADLDKS
>NC_008312.1|WP_011613656.1|6688072_6690226_-|WYL-domain-containing-protein
MNKPLICHFLIGPPGSGKSTFATKLSTLGDYTIISTDTIRSKLYGNETIQGEWREIEATLLKQITQSIKAGIPIIYDATNAIRPYRIALLKKLPQKNCAWIAWHLKTSLPTCLKWNKQRTRKVPETTVKKMFLSLKNFQPIIAEGFAAVHTLQKPNFNPKTIQEKIDSLTRSSVNRQNRLSCLEFHSYSRLLDFERLMHLIALFIKYPGLGNLEQTEPDILIAIFKEVPEFPDALAEIVAVIALLKGEVYADREAIATDLAWLEKNGIVAEGQTVTPAILRQEISPQPLTKRGKKKNGTSDLPLKRKKGKEIKARSENNSEQDIIPHPYSDIAPFKRLITAIRLILNRPFLRNDDQKSLDIFAEELSKQPGIGGNCRDKFRKDVEYILKPFHILPEFPMRRGYFAGTGILSQEQLKRLQDILQGQVKSIEDPMALSTYDQFCQRMISSKINIEKPYPIRAIAHKSMIDLEFVDENVLSRKLDQIEEFIIHGKLVELERLKGKGKFSGGEEGKFSVRLLQIVFFNNAWYLGFEYEGGTFNGLFRFERLDRLRISQDLGKSCPEKQRSKLERLQKLLDASFGIFLGYKAEDQSKFLSKDKKKKKEVIVTVELWFNQEKFEFVCEKTKLFPSGTLKMSPPPQGSSFIQKKEYEKIFDLEGTKNKHFPYRFRVELPCWCIEDVSFLSWVIGFGGHVKVKKPDELIDSVYEIGLGIVEVYDQ
>NC_008312.1|WP_044136979.1|6685741_6687259_+|SagB/ThcOx-family-dehydrogenase
MAEVKQSIAQYYHEQTKYDPETIGRKNHQLDWENQPIQFKEYKFGTTIDLKPYLQEKIQQKDPKEEENLSNLLVCTYGLTGKIPTMMGNHYLRAAPSAGGLYPAEVYLISRGTPLLPTGLYNYQAKTHSLLKFWDNRVWPELQDACFWHPALENTKLAIAITAIFYRSAWRYEDRAYRRIFLDAGHLLGNVELASSFSNYRSHLIGGFNDEAINQMLYLDNQEEQAIAIVALADLLDIEQHLPHWQAALPSGTQTDYPKIQEGDLLKYLHKATHINSNSPKVSAWKTRATLEHSEDKYNFPFCTKISTVTPPISWGQDLQGLRKTILKRRSTRSYSGETIALNKLLAVLDFTYQPHHYINQELDRNPDYFDISLIETFIAVSGVNDLEDGCYYYAPIAQELRQIRFKNFRKELHFMCLGQDLGRDAAAVLFHTADLKKAVSKYGDRVYRYLHSDAGHLGQRLNLAAIYLGLGVSGIGGFFDDHVNQVLGIPVDEAVIYITTLGSI
>NC_008312.1|WP_044137884.1|6683810_6684332_-|pentapeptide-repeat-containing-protein
MENMNAEELLWRYAEGQREFSGIDLSNIELFEANLEGINLEGCNLTRAYLPYANLNQANLQGCNLLEVKMGDIQLYKANLSNTNIQQGHLSRANLRHANLQGANLRGINLQGANLYHANLRDTDLRYGDLRGTNLEKAKLDNAKLGWCNLFRARIVDLSMAEYDHTTINPNGY
>NC_008312.1|WP_011613653.1|6682447_6683443_-|ketol-acid-reductoisomerase
MARMYYDSDANLDILNDKTIAIIGYGSQGHAHALNLKDSGSKVIVGLYSGSKSATKAKDAGLDVYPVDEAAEKADLIMILLPDEVQKTVYKNQIEPHLKEGKILAFAHGFNIHFGQIIPPENVDVVMVAPKGPGHLVRRTYEQGEGVPCLFAIFQDASGQGRDRAMAYAKGIGGTRAGILETTFREETETDLFGEQVVLCGGLSALIKAGFETLVKAGYQPELAYFECLHEVKLIVDLVVEGGLANMRDSISNTAEFGDYTRGPRIVTDETRAQMQKILSEIQSGQFAREFVMENQTGKPVFTAMRRQEAEHSIEEVGKDLRAMFSWLKKR
>NC_008312.1|WP_011613652.1|6682092_6682311_+|hypothetical-protein
MNKNLILLFFIVAIVFVSFGDSLEFIPEPIQNASFKSRKFAVGLWPDWLKPKNRNERTEEALEKLENPDQTE
>NC_008312.1|WP_155994551.1|6699115_6699298_+|hypothetical-protein
MEKSFILYGNQLKNGNVVFILQMDGKYMPRPINDGDKIISKTFMTRVEGENTRLRHYLAR
>NC_008312.1|WP_011613664.1|6699592_6700990_-|Rieske-2Fe-2S-domain-containing-protein
MIANTIKKSDNIPVSAGGTDPEYFDWQEVWYPIYYIEDLEKNKPTTFTLLEQDLVIWWEEKNNQWRVFEDQCPHRLAPLSQGRINEAGCLECPYHGWAFSGGGNCEIIPQQIAGGKAEKSSRAKVKSLPTKVCQGLLFVYAGKIENAAQTPIPKVDVLDENSNEWICLNTFRDVPYDGLTLMENVLDASHIPYTHHRTVGNRANVAPVELEVLESGKWGFKGVWEEGPRKGTLGRQETTFIAPGMMWHDLTSKQFGRTLTVVYATPIRKGECRLFARFPFKFSSPLPKFFIQLSPRWYSHIGQNGVLEDDQIFLHYQERYLEAKGGSANFSKAFYLPTKADLFVFELRSWVNKYNAQLFPNATLSSALNSEILLDRYHSHTKKCSSCRRALKNLQRIKVGVVLVTSFIWASIFFMLLILDDFNMTLMTFLILSLPVGVVFWLLLSKLEKQFYQGREIPPRNLLNN
>NC_008312.1|WP_071820711.1|6701529_6701619_-|cytochrome-b6-f-complex-subunit-PetN
MDILSLGWVSILVLFGFSISMVVWGRNGF
>NC_008312.1|WP_011613665.1|6702575_6702854_+|MoaD/ThiS-family-protein
MNNPKITITLKLFAVYQEAYKVPEVQLSISHGTTVSQLLERVISQYPELEKWQDVTKFGINLNFVPPETILQNGDEVVLIPPVSGGLHDFRI
>NC_008312.1|WP_011613666.1|6703128_6704442_+|threonine-synthase
MTHATKTHNQIETTNTAVENLRCKECGEEYPLEAKHICEDVCFGPLEVKYNYEKLSQIVSRATIEAGPKSIWRYRHFLPVVTDNFIDVGTGMTPLVKSERLARRLGLKNLYIKNDAVNMPTLSFKDRVVSVALSRARELGFSTVSCASTGNLANSTAAIAAKAGLECCVFIPADLEAGKVLGTLIYNPTLMAVKGNYDQVNRLCCEVANSYGWGFVNINLRPYYSEGSKTLGFEVAEQLGWQLPDHVVAPIASGSLYTKIYKGFQEFIKVGLVEDKAVRFSGAQAEGCSPVAQAFKEERDFISPVKPNTIAKSIAIGNPADGVYALELARKTNGNIESVNDTEIIEGIKLLAETEGIFTETAGGTTIAVLKKLVEAGKIDPEETTVVYITGNGLKTQEAVQGYVGEPLTIEAKLDSFERAWERAQTLERLDWQQVLV
>NC_008312.1|WP_011613667.1|6704734_6705010_+|MoaD/ThiS-family-protein
MAIKVLIPTALQKFTNNESQIECSAGNILDLIESLEAKYPGIKKSLCDDKGEPRRFLNFYVNSEDIRFLEGTKTSIKDGDEVSIVPAVAGG
>NC_008312.1|WP_011613668.1|6705408_6706437_+|peptidoglycan-binding-protein
MELKDFLGTDLKYDVKALADDEYLTCEIQAILIDLNMLNPPIDGIFGPLTTAALHRFQVEQKSGEAGYLGEKTIKKLWDAKEANIFAAPIILRTTKETILKLRPLLSSQLSDSEKHQMSAHQEFELLAYTPVRNHFRVAFRNYKYNGLGVWYVDEKKVEIYENNQVVHPKLKPESIKIKVPYKTKLDDLYNPTGLCNITSIASCLEFLEVNRKSNYGEFEDELYEYALSQGYSRHHPYHLVKIIRDYGCKDTFKTHATIQEVQDSLIAGNPVAIHSYFTSFGHLIVGVGFDNKGLFIHDPYGEWSSTKYRTDLSGACLHCSYELIRNVCMPDGNFWVHFISK
>NC_008312.1|WP_155994726.1|6707506_6708418_-|SUMF1/EgtB/PvdO-family-nonheme-iron-enzyme
MTGFRLVCDGGKTQHISPPQISQPQTSQPEKGKLFTFEVVRVNASGSIVNRRQESARQIIEDLGNGVSLEMVKIPGGRFLMGSPDTEAERLDKEGPQHYVDVPEFWMGKYVVTQQQWQAIMGNDPSEFKGKNRPVECVSWNNATEFCQKLSKKTGRDYRLPSEAEWEYACRAGTTTPFYFGETITTELVNYDGNYTYGNGPKGKYREQTTPVGQFPANAFGLYDMHGNVWEWCADEWHNNYAGAPTDGSVWLNGNKERSPLRGGSWLNLPINCRSAVRNYFYRRVDLNYDTGFRLVCDGGRTL
>NC_008312.1|WP_011613670.1|6710539_6711412_-|carboxylating-nicotinate-nucleotide-diphosphorylase
MKGVIPPKIILDNLLKDWLLEDIGRGDRTTSGLLLEDEVIVGTGHWLIKEPGVIAGLPIAARVFELLDQQVNFLPTVAEGEWCEKGTVVAKLDGSLDSLLTGERVALNLGMRLSGIATMTRKYVEKIAGLPVQLVDTRKTTPGLRILEKYATQVGGAKNHRMGLDDGVMIKDNHIAAAGGIGEAIAKVRERIPYPLTIEVETETLVEVERALEHQADIIMLDNMSVEVMEQAVKMIRQNNSRIKIEASGNITLETIRNVAETGVDYISTSAPITRSTWLDLSMKITKAVS
>NC_008312.1|WP_011613671.1|6712498_6712870_-|hypothetical-protein
MESSLNFLTSEESAQVDAALLTSKDKFSTRLAIYSLRCLRQIARETGLTLEEIPAEQVKAWMQKDKSLKQNLDSDPSFESFFTRLVMASLSPLKQVAQESAVALQDLTVQQVVKWFEKKGKIQ

Crispr_ID: NC_008312_44

• CRISPR_ID: NC_008312_44
• CRISPR_location: 6722416-6722496
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NC_008312_44

Consensus_repeat	Method
TTATATATGTTGGTGATATTTTG	CRISPRCasFinder

spacers of NC_008312_44

>44.1|6722439|35|NC_008312|CRISPRCasFinder
GTCAGTAAAAAAAAAATTAAGAATTAATTAAAAGG

CRISPR arrays and Neighbor proteins around NC_008312_44

CRISPR arrays

The CRISPR arrays of NC_008312_44

>merge|NC_008312|44|6722416-6722496|CRISPRCasFinder
TTATATATGTTGGTGATATTTTGGTCAGTAAAAAAAAAATTAAGAATTAATTAAAAGGTTATATATGTTGGTGATATTTTG

>NC_008312|44|35|6722416-6722496|CRISPRCasFinder
TTATATATGTTGGTGATATTTTG	GTCAGTAAAAAAAAAATTAAGAATTAATTAAAAGG
TTATATATGTTGGTGATATTTTG

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_008312.1|WP_011613685.1|6731612_6732389_-|PEP-CTERM-sorting-domain-containing-protein	unknown	unknown	unknown
NC_008312.1|WP_011613671.1|6712498_6712870_-|hypothetical-protein	unknown	unknown	unknown
NC_008312.1|WP_155994553.1|6733853_6734009_+|hypothetical-protein	unknown	unknown	unknown
NC_008312.1|WP_011613686.1|6735475_6736471_+|aspartate-carbamoyltransferase	unknown	unknown	gnl|CDD|234849
NC_008312.1|WP_011613680.1|6723029_6725207_-|tetratricopeptide-repeat-protein	unknown	unknown	gnl|CDD|274350
NC_008312.1|WP_011613675.1|6716834_6718196_+|Fe-S-cluster-assembly-protein-SufD	unknown	unknown	gnl|CDD|223791
NC_008312.1|WP_011613672.1|6713060_6713747_-|iron-sulfur-cluster-biosynthesis-transcriptional-regulator-SufR	unknown	unknown	gnl|CDD|131749
NC_008312.1|WP_011613682.1|6726972_6727329_-|hypothetical-protein	unknown	unknown	unknown
NC_008312.1|WP_011613670.1|6710539_6711412_-|carboxylating-nicotinate-nucleotide-diphosphorylase	unknown	unknown	gnl|CDD|236017
NC_008312.1|WP_155994554.1|6734526_6734700_+|hypothetical-protein	unknown	unknown	unknown
NC_008312.1|WP_071820769.1|6721500_6721974_-|hypothetical-protein	unknown	unknown	unknown
NC_008312.1|WP_081432500.1|6734775_6734889_+|PEP-CTERM-sorting-domain-containing-protein	unknown	unknown	unknown
NC_008312.1|WP_011613684.1|6728534_6730526_+|precorrin-3B-C(17)-methyltransferase	unknown	unknown	gnl|CDD|381173
NC_008312.1|WP_011613677.1|6720750_6721128_+|DUF4177-domain-containing-protein	unknown	unknown	gnl|CDD|379366
NC_008312.1|WP_044137890.1|6716046_6716829_+|Fe-S-cluster-assembly-ATPase-SufC	unknown	unknown	gnl|CDD|214372
NC_008312.1|WP_011613676.1|6718582_6719845_+|SufS-family-cysteine-desulfurase	unknown	unknown	gnl|CDD|215460
NC_008312.1|WP_011613683.1|6727532_6728279_+|hypothetical-protein	unknown	unknown	gnl|CDD|309752
NC_008312.1|WP_155994726.1|6707506_6708418_-|SUMF1/EgtB/PvdO-family-nonheme-iron-enzyme	unknown	unknown	gnl|CDD|224182
NC_008312.1|WP_011613673.1|6713997_6715434_+|Fe-S-cluster-assembly-protein-SufB	unknown	unknown	gnl|CDD|236990
NC_008312.1|WP_011613681.1|6725214_6726819_-|CHAT-domain-containing-protein	unknown	unknown	gnl|CDD|378942

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_008312.1|WP_011613686.1|6735475_6736471_+|aspartate-carbamoyltransferase	gnl|CDD|234849	PRK00856, pyrB, aspartate carbamoyltransferase catalytic subunit.	1.9917e-174
NC_008312.1|WP_011613680.1|6723029_6725207_-|tetratricopeptide-repeat-protein	gnl|CDD|274350	TIGR02917, TPR_domain_protein, putative PEP-CTERM system TPR-repeat lipoprotein. This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.	8.40019e-21
NC_008312.1|WP_011613675.1|6716834_6718196_+|Fe-S-cluster-assembly-protein-SufD	gnl|CDD|223791	COG0719, SufB, Cysteine desulfurase activator SufB [Posttranslational modification, protein turnover, chaperones].	7.58057e-105
NC_008312.1|WP_011613683.1|6727532_6728279_+|hypothetical-protein	gnl|CDD|309752	pfam04755, PAP_fibrillin, PAP_fibrillin. This family identifies a conserved region found in a number of plastid lipid-associated proteins (PAPs), and in a number of putative fibrillin proteins.	0.000631215
NC_008312.1|WP_011613670.1|6710539_6711412_-|carboxylating-nicotinate-nucleotide-diphosphorylase	gnl|CDD|236017	PRK07428, PRK07428, carboxylating nicotinate-nucleotide diphosphorylase.	0
NC_008312.1|WP_011613672.1|6713060_6713747_-|iron-sulfur-cluster-biosynthesis-transcriptional-regulator-SufR	gnl|CDD|131749	TIGR02702, transcriptional_regulator, iron-sulfur cluster biosynthesis transcriptional regulator SufR. All members of this cyanobacterial protein family are the transcriptional regulator SufR and regulate the SUF system, which makes possible iron-sulfur cluster biosynthesis despite exposure to oxygen. In all cases, the sufR gene is encoded near SUF system genes but in the opposite direction. This DNA-binding protein belongs to the the DeoR family of helix-loop-helix proteins. All members also have a probable metal-binding motif C-X(12)-C-X(13)-C-X(14)-C near the C-terminus. [Biosynthesis of cofactors, prosthetic groups, and carriers, Other, Regulatory functions, DNA interactions].	9.32571e-102
NC_008312.1|WP_011613684.1|6728534_6730526_+|precorrin-3B-C(17)-methyltransferase	gnl|CDD|381173	cd11646, Precorrin_3B_C17_MT, Precorrin-3B C(17)-methyltransferase (also named CobJ or CbiH). Precorrin-3B C(17)-methyltransferase participates in the pathway toward the biosynthesis of cobalamin (vitamin B12). There are two distinct cobalamin biosynthetic pathways. The aerobic pathway requires oxygen, and cobalt is inserted late in the pathway; the anaerobic pathway does not require oxygen, and cobalt insertion is the first committed step towards cobalamin synthesis. This model includes CobJ of the aerobic pathway and CbiH of the anaerobic pathway, both as stand-alone enzymes and when CobJ or CbiH form part of bifunctional enzymes, such as in Mycobacterium tuberculosis CobIJ where CobJ fuses with a precorrin-2 C(20)-methyltransferase domain, or Bacillus megaterium CbiH60, where CbiH is fused to a nitrite and sulfite reductase-like domain. In the aerobic pathway, once CobG has generated precorrin-3b, CobJ catalyzes the methylation of precorrin-3b at C-17 to form precorrin-4 (the extruded methylated C-20 fragment is left attached as an acyl group at C-1). In the corresponding anaerobic pathway, CbiH carries out this ring contraction, using cobalt-precorrin-3b as a substrate to generate a tetramethylated delta-lactone.	1.68194e-132
NC_008312.1|WP_011613677.1|6720750_6721128_+|DUF4177-domain-containing-protein	gnl|CDD|379366	pfam13783, DUF4177, Domain of unknown function (DUF4177).	1.28455e-07
NC_008312.1|WP_044137890.1|6716046_6716829_+|Fe-S-cluster-assembly-ATPase-SufC	gnl|CDD|214372	CHL00131, ycf16, sulfate ABC transporter protein; Validated.	1.91024e-148
NC_008312.1|WP_011613676.1|6718582_6719845_+|SufS-family-cysteine-desulfurase	gnl|CDD|215460	PLN02855, PLN02855, Bifunctional selenocysteine lyase/cysteine desulfurase.	0
NC_008312.1|WP_155994726.1|6707506_6708418_-|SUMF1/EgtB/PvdO-family-nonheme-iron-enzyme	gnl|CDD|224182	COG1262, COG1262, Uncharacterized conserved protein [Function unknown].	6.72348e-79
NC_008312.1|WP_011613673.1|6713997_6715434_+|Fe-S-cluster-assembly-protein-SufB	gnl|CDD|236990	PRK11814, PRK11814, cysteine desulfurase activator complex subunit SufB; Provisional.	0
NC_008312.1|WP_011613681.1|6725214_6726819_-|CHAT-domain-containing-protein	gnl|CDD|378942	pfam12770, CHAT, CHAT domain. These proteins appear to be related to peptidases in peptidase clan CD that includes the caspases. This domain has been termed the CHAT domain for Caspase HetF Associated with Tprs. This family has been identified as a sister group to the separins.	2.69156e-19

Protein sequences

>NC_008312.1|WP_071820769.1|6721500_6721974_-|hypothetical-protein
MNKILKIVSTILILATGLGVAIKVNYANNHLVADKSHNHINHSHKNIEIPSEKPVPKVDLFVYQDTMKGWNLHIKLTNFQFSPETVNQNSNINEGHAHLYINDKKITRIYSNWYYLGNLEPGKNKITVSLNTNKHENLVSNNQMIMDTEIIEVVAQK
>NC_008312.1|WP_011613677.1|6720750_6721128_+|DUF4177-domain-containing-protein
MREWNLNKLIVINLIVLNVAIILLAIVLIFFPYQTLATSTPKPQGKTESKTEFVNSEKLSQGRKRRYEYKVEYQFGFPQSEQERDNYTKALNEAGKDGWELSQTNVVFNPTNGQGLYILIFKREK
>NC_008312.1|WP_011613676.1|6718582_6719845_+|SufS-family-cysteine-desulfurase
MTIIQERTLAEKLRADFPILNQEINGEPLIYLDNAATSQKPLAVINAWQEYYLKYNSNVHRGIHTLSSKATDAYEGARDKVAALINAASRNEIIYTRNASEAVNLVAYSWGLNNLKSGDEIIVSVMEHHSNFVPWQMVAQKTGSVLKFVELNETEELNLEQYKALISDKTKLVALAHVSNVLGCINPIQEICSIAHKNGAKVLIDACQSVPHCVVDVQSIDCDWLVASGHKMCAPTGIGFLYGKLELLKEMPPFLGGGEMISEVFLDHYTYAELPHKFEAGTPAIGEAIALGAAVDYLTNIGMEKIHNYEVELTTYLFNKLRQIPQITIYGPQPNTYGEGRGTLVSFTVENIHPNDLSTMLDEAGIAIRSGHHCAQPLHQYLKVSSTARASLSFYNTRDDIDIFVDALKDTINFFADIMG
>NC_008312.1|WP_011613675.1|6716834_6718196_+|Fe-S-cluster-assembly-protein-SufD
MQISVKPEIFYLDKLLEESCKKVSPAIASDFSLDVKMAAWLQQVRDRAAAWVRELSIPTKKDEEWRFTNLSSMMKLSFQAPTLVDLDALNIAPFILPEVADSRLVFVNGVFAPQLSEVKGIENQVFVGNLGQLPEEYQKRVGNYLAQQPGSEEVFTCLNTAGLTDAAVVWLPKNQVLEKPIHLLFIATETEIPILTQRRCLVVAESNSSGKIIEHCVTAEVICPEAPNSHPYLTNTVTEIWVEENAEIDHTRVQRDAGAAFHIGKTAIAQAKNSRYTCNAINLGGRLSRHNLEVVQMGEGTETNLYGLAFLRNEQEIDTHSSITLNYPNSVTDQLYKCIVDDKAHSIFNGKIYVSQTAQLTNAAQLNRNLLLSSGGRVDTKPQLEIIADNVQCSHGATVSQLDDDEVFYLQSRGLSQEASRNLLIDAFAAEILNKLPLPSLQRILKQCVACKI
>NC_008312.1|WP_044137890.1|6716046_6716829_+|Fe-S-cluster-assembly-ATPase-SufC
MIKENSEVILSVKNLTANVEGKEILKGFNLEIKAGEIHAIMGPNGSGKSTFSKVLAGHPAYEVTGGEVTFLGKNLFDMEPEERSLNGVFLAFQYPLEIPGVSNLDFLRVAYNTKQKYQGLEELDAFDFDDLVQDKLDVVKMKPEFLDRSVNEGFSGGEKKRNEILQMALLEPKLAILDETDSGLDIDALRIVANGVNKLANESNSLLIITHYQRLLNYIVPDFVHVTESGRIIKTGTKELALELEEKGYDDVTEVAKVGV
>NC_008312.1|WP_011613673.1|6713997_6715434_+|Fe-S-cluster-assembly-protein-SufB
MTAKVTSLVNQPYKYGFVTDIESDTIPRGLSEDIVRLISAKKNEPEFMLNFRLKAYKKWLQMKEPLWAHVDYPKIDYQNIIYYSAPKLQDKKKSLEEVDPTLLETFEKLGIPLSEQKRLSNVAVDAVFDSVSVATTFKEKLAEEGVIFGSISEAVQEHPELVEKYLGSVVPVGDNFFAALNSAVFSDGSFVFIPKGVKCPMDLSTYFRINNGESGQFERTLIVAEEGSSVTYLEGCTAPMFDTNQLHAAVVELVTLDNAEIKYSTVQNWFAGDENGKGGIYNFVTKRGLCKGVNSKISWTQVETGSAITWKYPSCVLVGDNSVGEFYSVALTNNKQQADTGTKMVHVGKNTRSTIISKGISAGNSANSYRGLVKMGPGAKGSRNYSQCDSMLIGDRAQANTFPYIQVDNNTAKVEHEASTSKIGVDQLFYFAQRGISPEDAVSMIISGFCKDVFNELPMEFAAEADKLLSLKLEGTVG
>NC_008312.1|WP_011613672.1|6713060_6713747_-|iron-sulfur-cluster-biosynthesis-transcriptional-regulator-SufR
MMETTQQNSTKQEILQHLMKQTQATALELAKSLEISPQAIRRHLKDLEREGLITYKSVGTGTGRPQHIYELTTQGRDRFPHSYDKFAVSFLDTFAETMGHEQLSQVLHEQWQRKAMHYRQLLGTGSVQERMAQLVEIRKAEGYMAELYPNEQVKTQNSQFKSDSSLEEVEGYILIEHNCAISNVAESFPIVCGHELEMFGAVLPDCTVERTHSIVNGEHRCGYLITKK
>NC_008312.1|WP_011613671.1|6712498_6712870_-|hypothetical-protein
MESSLNFLTSEESAQVDAALLTSKDKFSTRLAIYSLRCLRQIARETGLTLEEIPAEQVKAWMQKDKSLKQNLDSDPSFESFFTRLVMASLSPLKQVAQESAVALQDLTVQQVVKWFEKKGKIQ
>NC_008312.1|WP_011613670.1|6710539_6711412_-|carboxylating-nicotinate-nucleotide-diphosphorylase
MKGVIPPKIILDNLLKDWLLEDIGRGDRTTSGLLLEDEVIVGTGHWLIKEPGVIAGLPIAARVFELLDQQVNFLPTVAEGEWCEKGTVVAKLDGSLDSLLTGERVALNLGMRLSGIATMTRKYVEKIAGLPVQLVDTRKTTPGLRILEKYATQVGGAKNHRMGLDDGVMIKDNHIAAAGGIGEAIAKVRERIPYPLTIEVETETLVEVERALEHQADIIMLDNMSVEVMEQAVKMIRQNNSRIKIEASGNITLETIRNVAETGVDYISTSAPITRSTWLDLSMKITKAVS
>NC_008312.1|WP_155994726.1|6707506_6708418_-|SUMF1/EgtB/PvdO-family-nonheme-iron-enzyme
MTGFRLVCDGGKTQHISPPQISQPQTSQPEKGKLFTFEVVRVNASGSIVNRRQESARQIIEDLGNGVSLEMVKIPGGRFLMGSPDTEAERLDKEGPQHYVDVPEFWMGKYVVTQQQWQAIMGNDPSEFKGKNRPVECVSWNNATEFCQKLSKKTGRDYRLPSEAEWEYACRAGTTTPFYFGETITTELVNYDGNYTYGNGPKGKYREQTTPVGQFPANAFGLYDMHGNVWEWCADEWHNNYAGAPTDGSVWLNGNKERSPLRGGSWLNLPINCRSAVRNYFYRRVDLNYDTGFRLVCDGGRTL
>NC_008312.1|WP_011613680.1|6723029_6725207_-|tetratricopeptide-repeat-protein
MPEPLTLELYRKIGIAYHSLGKFERSIEYFQQQLIIAREIKDRQSESQALGNLGIVYQSLGHFERSIDSFQQQLPITRDIKDRQSESQALGNLGIVYQSLGHFERSINYFQQQLVITREIKDRQSESKALGNLGIVYQSLGHFERSIDSFQQQLAITQETKDRQSESKALGNLGIVYQSLGHFERSINYFQQQLAITREIKDRQSESKALGNLGICYENQGQYSKAEPLYLEALKMNKQLLGSTHPDVASNLNNLAGLYYSQGRYSEAEPLYLEALKMNKQLLGATHPEIASNLNNLAGLYYSQGRYSEAEPLYLEALKMNKQLLGATHPEIASNLNNLAILYRSQGRYSEAEPLYKQAIEINKIALPVNHPSRASSLNNLAGLYSNQERYSEAEPLYKQAIEINKIALPANHPFLASSLNNLASLYFNQGRYSEAEPLYKQAIEINKIALSANHPSLAFNLNNLAGLYSNQGRYSEAEALYKQAIEINKIALPANHPSLASSLENLAALYFNQGRYSEAEALYKQAIEINKIALPENHPSLASSLDNLAALYFNQGRYSEAEALYKQAIEINKIALPANHPSLASSLDNLATLYFNQGRYSEAEALYKQAIEINKIALPANHPSLASSFINLAGLYSNQGRYSEFEDTIAALREDLKTRNHLSNFCKIVENYLQDTDLSTFVEKYYSEIAESGYNREIDALVNNLDRHGHIELALNLLESIKKQ
>NC_008312.1|WP_011613681.1|6725214_6726819_-|CHAT-domain-containing-protein
MELLELYLSPLDDSTKFEVIVTDSPAGQGRNESLLPFLDAEWDWRITVIRSLEVSTFRPEFFSAQEQEWMSQAGILGSDRSNFHPNYLINIGKALYSSLFPPGSKVENLLQKSISFAESKSTKLLVRLKLDGDVAQKTRLADYPWELLHNQGFLCHYQVEFSRYIAYPSVPPNLPTAEKLNVLLVSSAASDHKLNLQPLSRKEQKAVLKGLEKARDRGDIFLAQLEEPTLDELRNYLTEHRGDKGPHVIHFDGHGLFGQRCPNSECGAMNGGTKSRRCRKCETELPLPQGYLVFEDKDGDADYISGQELGTLLQQSGLRDGNGKTEGVVLVVLSACQSGMAIVGESVFNGAAQSLIAHRVPAVVAMQYSVRVDSATKFAEQFYRSLGQKNSLAVAVSQGRAAMGVDGNQWYRPVLYLRWQDNEGGQLFVTQSTIKSINKSVNKPIPSNHPPIIEDQIKLSLRAIPNQNINNINSPEILVVDTVVDTLATLSELKAGLYKLYKKCKEPKILEEIEKIEHLEFNQKKLLQSELYSR
>NC_008312.1|WP_011613682.1|6726972_6727329_-|hypothetical-protein
MNDESSIGLAELIQQVKEELLTQAPDGETDIPIFAVDSVELELQVTVKKSGKAGIKIYVLEMGGGSSRDDVQKVKVKLSPLLNREQLLKMYQKKYPENWPEFLEKVSDAGMKGPEPNF
>NC_008312.1|WP_011613683.1|6727532_6728279_+|hypothetical-protein
MNNIATILETKMALREALKTYDGDVKNQKVKAKIEQLSQLNPIEKPTHSSLLESHWLLISAPSFPQGQKLSNGKYAYTLGKLAFNMFQPTNLKLVIDSVKQPVVLLGEKSKRSHDIVVEFSIIDELFPPLKGIVRNLAVCYPVDNKNLQAEFTGGIFAPQKGENLSTWKDIFVQAKASKKGLKEQLMSVFFKLMFGLTPPQGMNTETGEISFTMKRSPKGRLEILFLDEELRITKGKKENILIFERMV
>NC_008312.1|WP_011613684.1|6728534_6730526_+|precorrin-3B-C(17)-methyltransferase
MNVIGQEFQPIAAIATTPTGAKLLQPICQKLEGTLWIPESCRKTVNLSLNTQVYTDSLKNHLANIWLDYNAIIFSLASGAVIRLISPLLQNKYHDPAVVIVDQTGKFVISLCSGHQGGADQLTNILAPLLNATPVITGASHNLELPGIDILGKPFGWQRGEGDWNTVSGIIAREETVQVLQEVGSMLWQKHLPHQHPFYFGFPKMGETSPTPKARIWINFYQHQFSPDSDLPKVQWHPRVLWVGVGCERGTSKKLIATGIEKILSTYNLAVKAIAGIATINIKADEIGLIEFCQEKNLPLQTFSAELLNCVEVPNPSDIVAAEVGTTSVSEAAAILAAKQQQDTDFKQKYNVFEQEEIRDNKQESKLPLPGEFQQEKQQLKLSTNLLVSKEIFRLEGEPGAMTIAIALSEKEYTGRTGKLLLIGTGPGQLDQITSAAKTAISYADVVIGYSLYIDLIQPLFNPGQIVEKMPITQERQRAERAIELANFGLTVAVVSSGDSGIYGMAGLVLEQLRASYWDGKNPAVEIFPGISALQSAASRVGVPLMHDFCAISLSDLLTPWEVIEKRLIAAAMADFVVAIYNPKSQKRTEQLVKAVNIFLKYRQPKNPVAVVRSAYRENEEATLTTLDKLLEVSVDMLTVILIGNQSTGIYNNWMITPRGYLG
>NC_008312.1|WP_011613685.1|6731612_6732389_-|PEP-CTERM-sorting-domain-containing-protein
MKDKAQVSKKNTLTKTVQTTVAALASTVLLGVGNAQANTKNIFIDEFLDFQMVESTGPLTNSQVGPTGNILGGYRDIFVEVVNNNSNNPYLSSNLSVVNGEGSFNNDAGITGTGMIRWDGVNNSQTLNPQGLGGINITQGNLDSISMDIMLAEAAGLDMTFTIYDMNSNSSSISRILNSSTLTSKAETFLFQDFVGTADFTNVGAIQLDISSPESMDAIVGPVRISKSTPVPEPTSILGLLAIGAVGTGSMLKQKKNN
>NC_008312.1|WP_155994553.1|6733853_6734009_+|hypothetical-protein
MTNIITLIAIASPSIATTFTLTDIPYSETLLLSVEQEENQYQEPGKIVVLN
>NC_008312.1|WP_155994554.1|6734526_6734700_+|hypothetical-protein
MKQNGNFYLGVGNNYFIKPETSWTKKYLTNLTESNFQLIGGGVNQHPDFSEQDVDIQ
>NC_008312.1|WP_081432500.1|6734775_6734889_+|PEP-CTERM-sorting-domain-containing-protein
MVVTIEKQETAPVPEPTSTVGIVVLVAIALFRHKRHS
>NC_008312.1|WP_011613686.1|6735475_6736471_+|aspartate-carbamoyltransferase
MSTNIWTPRHILSLAEFTPTEYNIILQTATSFQEVLGRRMKKVPALQGQVVANLFFEPSTRTRNSFELAAKRLSADTLNFAPGTSSLTKGETILDTAMTYLAMGTDMMVIRHRNAGVPAAIASAMDRNGHQVRVLNAGDGQHEHPSQALLDLFTICKLLNSTEPRIELLETKKIAIVGDILHSRVARSNIWSLTASGAEVHLAGTPTLLPKYFGEFGKLRPSKLFVHWDIEPALEKADFVMTLRLQKERMSQHLLPSLREYHQLFGITRDRLKLCQPGVKILHPGPVNRGVEISSDLMDDPQLSLISQQVTSGIAVRMALLYLLGGGKADQ

Crispr_ID: NC_008312_45

• CRISPR_ID: NC_008312_45
• CRISPR_location: 6864476-6864889
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 8 spacers
• Cas_protein_info: PD-DExK

Consensus repeat of NC_008312_45

Consensus_repeat	Method
TGGCGTTNGGCGTGGCGT	CRT

spacers of NC_008312_45

>45.1|6864494|18|NC_008312|CRT
TAGGCGTGGCGGTTGGCG
>45.2|6864530|18|NC_008312|CRT
TCGGCGTGTCGGAAGGCG
>45.3|6864566|42|NC_008312|CRT
TAGGCGTGGCGTTAGGCGTGGCGTTCGGCGTGGCGGTTGGCG
>45.4|6864626|54|NC_008312|CRT
TAGGCGTGGCGGGAGGCGTGGCGTTCGGCGTGGCGGTTGGCGTGGCGGTTGGCG
>45.5|6864698|18|NC_008312|CRT
ACGGCGTGGCGGGAGGCG
>45.6|6864734|30|NC_008312|CRT
ACGGCGTGGCGGTTGGCGTGGCGGTTGGCG
>45.7|6864782|18|NC_008312|CRT
TCGGCGTGGCGTTAGGCG
>45.8|6864818|54|NC_008312|CRT
TTGGCGTGGCGTTCGGCGTGGCGGTTGGCGTGGCGGTTGGCGTGGCGGTTGGCG

CRISPR arrays and Neighbor proteins around NC_008312_45

CRISPR arrays

The CRISPR arrays of NC_008312_45

>merge|NC_008312|45|6864476-6864889|CRT
TGGCGTTAGGCGTGGCGTTAGGCGTGGCGGTTGGCGTGGCGTTCGGCGTGGCGTTCGGCGTGTCGGAAGGCGTGGCGTTCGTCGTGGCGTTAGGCGTGGCGTTAGGCGTGGCGTTCGGCGTGGCGGTTGGCGTGGCGTTCGGCGTGGCGTTAGGCGTGGCGGGAGGCGTGGCGTTCGGCGTGGCGGTTGGCGTGGCGGTTGGCGTGGCGTTAGGCGTGGCGTACGGCGTGGCGGGAGGCGTGGCGTTAGGCGTGGCGTACGGCGTGGCGGTTGGCGTGGCGGTTGGCGTGGCGGGAGGCGTGGCGTTCGGCGTGGCGTTAGGCGTGGCGTTAGGCGTGGCGGTTGGCGTGGCGTTCGGCGTGGCGGTTGGCGTGGCGGTTGGCGTGGCGGTTGGCGTGGCGTTAGGCGTGGCGG

>NC_008312|45|7|6864476-6864889|CRT
TGGCGTTAGGCGTGGCGT	TAGGCGTGGCGGTTGGCG
TGGCGTTCGGCGTGGCGT	TCGGCGTGTCGGAAGGCG
TGGCGTTCGTCGTGGCGT	TAGGCGTGGCGTTAGGCGTGGCGTTCGGCGTGGCGGTTGGCG
TGGCGTTCGGCGTGGCGT	TAGGCGTGGCGGGAGGCGTGGCGTTCGGCGTGGCGGTTGGCGTGGCGGTTGGCG
TGGCGTTAGGCGTGGCGT	ACGGCGTGGCGGGAGGCG
TGGCGTTAGGCGTGGCGT	ACGGCGTGGCGGTTGGCGTGGCGGTTGGCG
TGGCGGGAGGCGTGGCGT	TCGGCGTGGCGTTAGGCG
TGGCGTTAGGCGTGGCGG	TTGGCGTGGCGTTCGGCGTGGCGGTTGGCGTGGCGGTTGGCGTGGCGGTTGGCG
TGGCGTTAGGCGTGGCGG

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_008312.1|WP_011613774.1|6883491_6885699_+|DUF839-domain-containing-protein	unknown	unknown	gnl|CDD|225752
NC_008312.1|WP_044136991.1|6859583_6860168_+|biopolymer-transporter-ExbD	unknown	unknown	gnl|CDD|223917
NC_008312.1|WP_011613763.1|6863317_6863929_+|hypothetical-protein	PD-DExK	mkCas0061_PD-DExK_CAS-I:CAS-III	unknown
NC_008312.1|WP_044137908.1|6849707_6850010_+|helix-turn-helix-transcriptional-regulator	unknown	unknown	gnl|CDD|238045
NC_008312.1|WP_011613768.1|6872162_6873455_+|PQQ-dependent-sugar-dehydrogenase	unknown	unknown	gnl|CDD|369642
NC_008312.1|WP_011613765.1|6867811_6868915_+|hypothetical-protein	unknown	unknown	unknown
NC_008312.1|WP_011613761.1|6861232_6861625_-|hypothetical-protein	unknown	unknown	unknown
NC_008312.1|WP_011613770.1|6874975_6878719_+|tetratricopeptide-repeat-protein	unknown	unknown	gnl|CDD|378942
NC_008312.1|WP_011613766.1|6869159_6870812_+|mechanosensitive-ion-channel	unknown	unknown	gnl|CDD|366370
NC_008312.1|WP_011613758.1|6858459_6859245_+|MotA/TolQ/ExbB-proton-channel-family-protein	unknown	unknown	gnl|CDD|223881
NC_008312.1|WP_155994563.1|6860456_6860786_-|hypothetical-protein	unknown	unknown	unknown
NC_008312.1|WP_011613769.1|6873869_6874376_-|ABC-transporter-substrate-binding-protein	unknown	unknown	gnl|CDD|377411
NC_008312.1|WP_011613756.1|6851334_6852024_+|hypothetical-protein	unknown	unknown	gnl|CDD|366639
NC_008312.1|WP_011613773.1|6882817_6883072_+|TIGR03643-family-protein	unknown	unknown	gnl|CDD|378528
NC_008312.1|WP_011613767.1|6871126_6871543_+|YjbQ-family-protein	unknown	unknown	gnl|CDD|376651
NC_008312.1|WP_011613762.1|6861867_6862968_+|AAA-family-ATPase	unknown	unknown	gnl|CDD|379165
NC_008312.1|WP_011613757.1|6852047_6857684_-|PAS-domain-containing-protein	unknown	unknown	gnl|CDD|236848
NC_008312.1|WP_011613772.1|6880578_6882291_+|bifunctional-3,4-dihydroxy-2-butanone-4-phosphate-synthase-RibB/GTP-cyclohydrolase-II-RibA	unknown	unknown	gnl|CDD|236465
NC_008312.1|WP_044137909.1|6850356_6851202_+|D-alanyl-D-alanine-carboxypeptidase	unknown	unknown	gnl|CDD|367124
NC_008312.1|WP_044137913.1|6879043_6879688_-|5,6-dimethylbenzimidazole-synthase	unknown	unknown	gnl|CDD|380321

HMMScan for Signature genes

Protein	Cas_name	Cas_description	E-value	Identity	Coverage
NC_008312.1|WP_011613763.1|6863317_6863929_+|hypothetical-protein	PD-DExK	mkCas0061_PD-DExK_CAS-I:CAS-III	1.7e-27	91.0	0.0

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_008312.1|WP_011613774.1|6883491_6885699_+|DUF839-domain-containing-protein	gnl|CDD|225752	COG3211, PhoX, Predicted phosphatase [General function prediction only].	3.66085e-100
NC_008312.1|WP_044136991.1|6859583_6860168_+|biopolymer-transporter-ExbD	gnl|CDD|223917	COG0848, ExbD, Biopolymer transport protein [Intracellular trafficking and secretion].	3.52875e-33
NC_008312.1|WP_011613766.1|6869159_6870812_+|mechanosensitive-ion-channel	gnl|CDD|366370	pfam00924, MS_channel, Mechanosensitive ion channel. Two members of this protein family of M. jannaschii have been functionally characterized. Both proteins form mechanosensitive (MS) ion channels upon reconstitution into liposomes and functional examination by the patch-clamp technique. Therefore this family are likely to also be MS channel proteins.	8.92733e-26
NC_008312.1|WP_044137908.1|6849707_6850010_+|helix-turn-helix-transcriptional-regulator	gnl|CDD|238045	cd00093, HTH_XRE, Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators.	9.91532e-11
NC_008312.1|WP_011613768.1|6872162_6873455_+|PQQ-dependent-sugar-dehydrogenase	gnl|CDD|369642	pfam07995, GSDH, Glucose / Sorbosone dehydrogenase. Members of this family are glucose/sorbosone dehydrogenases that possess a beta-propeller fold.	0
NC_008312.1|WP_011613770.1|6874975_6878719_+|tetratricopeptide-repeat-protein	gnl|CDD|378942	pfam12770, CHAT, CHAT domain. These proteins appear to be related to peptidases in peptidase clan CD that includes the caspases. This domain has been termed the CHAT domain for Caspase HetF Associated with Tprs. This family has been identified as a sister group to the separins.	8.61317e-52
NC_008312.1|WP_011613758.1|6858459_6859245_+|MotA/TolQ/ExbB-proton-channel-family-protein	gnl|CDD|223881	COG0811, TolQ, Biopolymer transport proteins [Intracellular trafficking and secretion].	2.27754e-51
NC_008312.1|WP_011613769.1|6873869_6874376_-|ABC-transporter-substrate-binding-protein	gnl|CDD|377411	pfam04832, SOUL, SOUL heme-binding protein. This family represents a group of putative heme-binding proteins. Our family includes archaeal and bacterial homologs.	3.58322e-10
NC_008312.1|WP_011613756.1|6851334_6852024_+|hypothetical-protein	gnl|CDD|366639	pfam01434, Peptidase_M41, Peptidase family M41.	8.32984e-05
NC_008312.1|WP_011613773.1|6882817_6883072_+|TIGR03643-family-protein	gnl|CDD|378528	pfam10985, DUF2805, Protein of unknown function (DUF2805). This is a bacterial family of proteins with unknown function.	6.98594e-41
NC_008312.1|WP_011613767.1|6871126_6871543_+|YjbQ-family-protein	gnl|CDD|376651	pfam01894, UPF0047, Uncharacterized protein family UPF0047. This family has no known function. The alignment contains a conserved aspartate and histidine that may be functionally important.	1.3241e-60
NC_008312.1|WP_011613762.1|6861867_6862968_+|AAA-family-ATPase	gnl|CDD|379165	pfam13401, AAA_22, AAA domain.	3.90901e-07
NC_008312.1|WP_011613757.1|6852047_6857684_-|PAS-domain-containing-protein	gnl|CDD|236848	PRK11107, PRK11107, hybrid sensory histidine kinase BarA; Provisional.	1.52559e-56
NC_008312.1|WP_011613772.1|6880578_6882291_+|bifunctional-3,4-dihydroxy-2-butanone-4-phosphate-synthase-RibB/GTP-cyclohydrolase-II-RibA	gnl|CDD|236465	PRK09319, PRK09319, bifunctional 3,4-dihydroxy-2-butanone-4-phosphate synthase RibB/GTP cyclohydrolase II RibA.	0
NC_008312.1|WP_044137909.1|6850356_6851202_+|D-alanyl-D-alanine-carboxypeptidase	gnl|CDD|367124	pfam02557, VanY, D-alanyl-D-alanine carboxypeptidase.	1.09052e-55
NC_008312.1|WP_044137913.1|6879043_6879688_-|5,6-dimethylbenzimidazole-synthase	gnl|CDD|380321	cd02145, BluB, 5,6-dimethylbenzimidazole synthase. BluB catalyzes the O2-dependent conversion of FMNH2 to 5,6-dimethylbenzimidazole (DMB), a component of vitamin B12; is is a subfamily of the nitroreductase family; nitroreductases typically reduce their substrates by using NAD(P)H as electron donor and often use FMN as a cofactor.	3.95167e-68

Protein sequences

>NC_008312.1|WP_011613763.1|6863317_6863929_+|hypothetical-protein
MSQHSILQENKSYTFGSYVELPDETEDILAEFNYNFKRAKFSLPTSHRQLKGLPELGGRIEESLPLVSLSSEAARPEVLIAPVLLQVARYCQCCLRIEYPLNINERLKSNLDYLLQANSQLLVIEAKNDDMTGGFRQLAVELIALSEWERERDLIFGCVTMGELWIFGFLDKKQCLIQQNIDSLRVPGDLEVLVDVLVGILEG
>NC_008312.1|WP_011613762.1|6861867_6862968_+|AAA-family-ATPase
MNNGLQWDDFLIIIANEYRLTKVEKEFFFKRFAKENLEKKDGEMSRLVMGNDSQEQTYRKRKSNVYKKFKDIINHDGKDKFPILLKKLEKEYQSRYFSQEITKSPLEPKNKVSNPFIPLSGVIDNSWLFFNREEEINSIFEVLNSGSSVAIIGEGGVGKSSLLKAIAQKADKYLEKPRKSIYIDLQNIQSDDDFYTALCEKVGIEISRGYLLQRNLKLHRILLLLDVVENISYDWFTNKLRSQLRGLASNFEPPLRLVIAASKSLDTLFPDSGDKTSPFENICIEEHLKPWNEKTIRNFINARLQADFLEPEYQGIKFGEDEILQIIESSKGYPRKVIHQCHELFKSKSYNSGLLNKSFQEGGTES
>NC_008312.1|WP_011613761.1|6861232_6861625_-|hypothetical-protein
MKKQNLCKKYYCLLIQYNSNNNYYVLRLKPKLGDPKKNHHLKNKNHGNKPILLLKSPNDDIYFQYNQIPWERKPKIRWHRLLKIAIAIITTLLTNFAPVNQEKLDTQTQTMEIIKNYATMTRIILEFYDK
>NC_008312.1|WP_155994563.1|6860456_6860786_-|hypothetical-protein
MIVAKKDKCQKSNLLYQRLQEALENGNKVRIEAEETYYGFPVTLTKDFVEIMVLVPPDEYDEEDDSFKQVTWLIRLSSIFAIAYPTEYWSTARLEKLLEVGSNHIGSRE
>NC_008312.1|WP_044136991.1|6859583_6860168_+|biopolymer-transporter-ExbD
MKLNQESISEEIRIELIPLIDVIFCILTFFLLAALQLTRQQAINVNLPKATTGKPQSQDMLLVSLDEVGKTFIDKQPVSTIELEKFVRRYNKLSPRGVVVLYAPKEAKYNDVVQVLDLLREVGGDRVALATLPGSPQTGAGNTSENPVTPFQEDNKNNPTGTTDADNTSDNLVTPSFPGRTVDPNKYKLPKAPE
>NC_008312.1|WP_011613758.1|6858459_6859245_+|MotA/TolQ/ExbB-proton-channel-family-protein
MTFEELIQKGGPAMWPLLVLSILSLSTIIDRIWFWTSLLIKEKQTVNRVLESARRDWSIATEMARRNQKQPIGRFLYAPLRLQHPEPEVFKLALEAAADDELASMRKGDKLLEGVIALAPMLGLLGTVLGLIGSLGSIRLGDLGTSSTAGVTVGIGEALISTATGLVVAIFSLVFYRLFQSLLFNQMKVFRKAGNELELLYRQYWQQVFLSSSSENQNPGFSTSFIQNTQNNINTLEPDQKPTDFLSENDPEQSQDNSHDQ
>NC_008312.1|WP_011613757.1|6852047_6857684_-|PAS-domain-containing-protein
MLIPSISQVINYHPLTATAETAVEDIIISMSSTGSSCVLITEKPSFSTSIKIVTPGDRSPGSPKGNHHSNSPDAKLQYLGPVIGIFTEGDLVQLASIGAPLSGFPIAQIMIRSIVTAQLSEIPDIFALFALFEKHKINHLPIVDNLERLIGLITGHSFLLNLNNIKKKGEKSILSRKKIKSQQKLSANQNNTVNKGLKSENNLLKNPNNQLLPQEITFDSSLELPGNFIPINHLEKTHESQVIQGSFSLSIKQITQLMSTHNVSYVLIIEATEKKYQNETDIYLNQESSNSQKSIKIIGTISSRDIVQLQALKIDFNKVKAGIVCNKSPIVIGSDVTLELAVDLINKKYCLLPLIVQNYIGKIDYFISPTKVIRQILLNKSLYQSLIRFYSYVEKTYLKLHQANKKLKQYTIEQNNLEKSQLAAPETTGITLKLDQDGIWDWNIETGEIFYSTLGEKMLGYTEHEISHKISFDEWLSRIHPEDRDKVNTAIQEHLTKKNTIYKIKYRIQGKDNNFIWIFDSGQTLWKSGKPVRMVGIFVDITKEKEAEIKQSFLVEKHIQIINNLSEIVWETDIHGNLIFLNQAWEKITGFKPKNSLGKNFLDYIHPEDINKLNFLTKNHPENTELAIIHNKLVADSYQLQLLTKTGGYCPVKMKSTLVFDRENKVTGIVSTLSNISEDIATQQQLQASQKAIKELYEVTTNADISFESKIVALLEMGCHRFGMDIGLLGQVLGELYKVIAAHLPENFLFGIAEGDIFTLEQTFDQEALQYDEPFVIESAKNSQWRHHPAHTVRHVESYIGTKILASGIVYGTLSFSSRLTKNKWSSIDIEVLKLMANYIGGELLREDERKALENKYQHFLLLKQITQEICSKLDTKEIFQTTVTQIGRAFKVSRCLIHSYVTEPDLHLPCMAEYLETNHESILGLDLIITSNYYTEKLLGEDRAIASPDVFSDPLLNSDVPMYQKLKVRSILAIRTSYQGKPNGIIHLHQCDYIRQWKQDEISLLEEVAFQVGLTLAKAQILESEVTHKEELEAENQALEKAREVAEVRNRAQGELLAMMSHKSQTNMNDVMMMTSLLLSMKLNPKQRDFVKTILARGDVVINMINNILDFTKIKSGEVELELSPLDIRGCVEDLLKSLDIIAKNKKLELAYLIDKNVPRIILTDDKKLVNILFNLLKNSINFTKTGEIVVYISAIKKSEKSQEYSQLEAISYEEISDFKGAGKITDNYEIQFAVKDTGAGIPLDQIDHLFKDFSQVSPATNREYDGLGLGLVISQRLSQMMGGQMWVVSQPLEIKNLSEEKKQISLLKIEDSRDINFPKNPINVYNSSSPESKVNIAGNPPHYFVKPELSGRGSIFYFTIQAKAIAMYSPEIVDGLLRGKKILVVESNIINQEEIKQQVKQWEMIPIVADSATKALSDLEQGKVFDLGIIAMDISDMDGLTLARKIRKLEAEQNSKQNKNDKSFLPLLMLNYIDTVDISRELQEAKVSLAGFLNIPIKQSQFYNVLLEVFGTRKEEEVNDKVPSLDMEDFQDLSEKNRDYTNIRILLAENNVVNQKVVIHLLEKIGYLADVAANKVEFLDALKRISYDVVLMDVQMNNGDGIGITNQICQRYSEEKRPWIIAMTANARSGDREKYLNAGMDDYMTKPVDQEKLVEVLNKFKRIRNQKLGSKTDLENAVRSHSSVIRSTLVKTNSSRQPVIQKPSFTNFQVESTSQSDEIISLKSTLPIVIPSNIEDVPETKEITMPGLDLLNDQQLAVDPKIIEKFCNLYYDEPDTPIILIQDYLTDGNKNINMIRNYINKGNFNALKTASQKFKTSSALLGAINFSKLCEELEKMALAVIESREDFDLEKATKIFLQSKNEWERVQKELSTKMNC
>NC_008312.1|WP_011613756.1|6851334_6852024_+|hypothetical-protein
MRQTSLNIIAIGIFVMTMSSLLGPIFNISPFYIAIATFSVLVLATIDTLGWQGQGSMILVDLVAGTSSEKRDRIICHEAGHFLVAYLLEIPISGYALNAWEAFRQGQSSQGGVRFDDQKLAAQLYSGVISSQLVDRYCTVWMAGIAAENLVYGNAEGGAEDRTKITAILRQLKRPGESKLKQSWASLQARNLLENHQSAYKALVKAMTERSSVSDCYQTIKEHLSVDQD
>NC_008312.1|WP_044137909.1|6850356_6851202_+|D-alanyl-D-alanine-carboxypeptidase
MNKLGLLKKTPDEAKLPVDDIPEAVRDEEESAKHQSFKPQKIWQIWQLLAMGAIALIISISWHFQFNKTLNTSPVVQMKQKISTKAVETSPTQLETPSPSPSFNSSIKQRENILGHLPYKEASWQELTPVFGNQNIRLRSIAAEKFDLMADVAWSANIELVPLSGFRTVGDQQYLFFEVKAERGQETSKRAEVSAPPGYSEHHTGYAIDIGDARMPETHLEVSFENTKAFQWLQENAENYGFELSFPKDNPQGISYEPWHWRFVGDSHSLKTFEEARSLKE
>NC_008312.1|WP_044137908.1|6849707_6850010_+|helix-turn-helix-transcriptional-regulator
MDMEALRERTGLTRAEVAYRLGISETSVRNWETGRTEPTMTPQKFLEILDILKCSPEELALASDKSISQRHKRKPGRPRKFIDNNDELDEAKTTESATGH
>NC_008312.1|WP_011613765.1|6867811_6868915_+|hypothetical-protein
MSRPTLYIAITNHGFGHAVRVSSVANLVQQMCPDVLLIMVTTAPYWLLESYIYGDFIYRPRSFDVGVIQSDSITMDKQTTLEKLQEIKKKEYSIIAGEVNFIKQNKVNLLLADIPPIAAKIAKSVDIPCWMLSNFGWDFIYRPWGGEFIEIANWISECFAQCNRLFRLPLHESMSAFPNIFDVGLTGGIPRYQPEEIRAKFNIHAEKEKTILLTFGGLGLDKIPYENIGAFPDWQFLTFDNDTPEILNLINVRKESQKKEINLPNIRPVDLMPICGRIVSKPGYSTFAEALRLEIPIVSLMREGFAESKLLLEGIQDYSYHQILPPTEFFHDDWEFLKQPLQAPRKSDKLDKNGSEAIAKFIVDYIQ
>NC_008312.1|WP_011613766.1|6869159_6870812_+|mechanosensitive-ion-channel
MIPEINLNNLIQIDLNSIILTVAEVGAIILIFLVIRFFFGKAYKQLIKVSSIKTNKKNVEIIYKNILTFLTISCLISCLLVVGVNGWLLFYQRENLIEYQTSLIKNISWNYLIAIGIRILKVLGILIITKWSIPYINKFITGLKERIKKIESINASDTSIEKLFDFLKSNFNNLIWVLYLIISAQIMLLPKVVINYLYIGLKIYIIIIIGLIFTKSNATIIYTFDAFSKKYSEKKNIFGFYERLKKLIPLAKRCFEYIIYTATATLVFKQVDFIAYLAPYGTKFIGVIGVIFMSRVFQEIGQLLLAQILLSQTDADDSSQQRRKTFFPLFKSCIKYLIYFCTGIVILYTIGIDPTPILAGVGIIGFAVGIGAQSLVEDIVAGFFILFENYYLVGDFVEINGIYGVVTGIELRTTRINYEDKNHIIHNRDVKDIVNYPSFGNAVVMLKIPYQVKISQVHKIIEKVGNKILEDYSTDIIEPTIIEGIEEFSEHQILAEIVTKVKPGKHLMIQKIVGLMIKEAFEEENIDLRVVNHIKLNNSKPIPIFLKGIE
>NC_008312.1|WP_011613767.1|6871126_6871543_+|YjbQ-family-protein
MTHYQQLLQVNTSGKSLSKITSKVKEAVLKSGVKTGLCNLFLRHTSASLIIQENADPDVLLDLEKFISKLVPEGNYYIHSAEGPDDMPAHIRSVLTHTSEQIPINNGKLVLGTWQGIYVWEHRQRGHQRDLVIHISGE
>NC_008312.1|WP_011613768.1|6872162_6873455_+|PQQ-dependent-sugar-dehydrogenase
MFQYNFFSQPEQKILDIFYGLIIKKSTILFRTAIAIALLGIVSCRTEIKLESSTATQTQNKSRINSSVSDAENMTSISDYQKITLVKNLEHPWSIAWLPDGKILITERPGRLRIFRDGILEPTPISGVPQVFAFGQGGLLDVSAHPRFAENRFIYLTYSHGDRSNNRTRIARARLENNTLGDLKVIFEVSQTKPGAQHFGSRIIWLPDGTLVASIGDGGNPPIEFNGEFIRQQAQNRNSHFGKVIRLNDDGSIPSNNPFATSTDAKPALWSYGHRNIQGITLDPTKNRVWATEHGSRGGDELNLIERGENYGWPVVTHSREYSGGLISPETSRPGLVDPKVIWTPSIAPSGLAFYNGDRFPQWRGNLFAGGLVSQDIRRIQLDPGGNVIAQNSIPIGQRVRDVRQGPDGLLYVLTDDRNGQLIRLEPMGK
>NC_008312.1|WP_011613769.1|6873869_6874376_-|ABC-transporter-substrate-binding-protein
MSVSLPQGFPQPTEVNIIEVKEYPQYRGITYTHTGDSRMATRVAFDPLYQHISTNQIAMTTPVEARYIKENQKTEVSFLYSTPELTPQKIDSQVAVRDTSPMTVVSIGVQGAYSWESYEQNLQKLKHWLTQHPEYEVVSAPRRLLYNSPMTPEDLKRSEVQIAISLKS
>NC_008312.1|WP_011613770.1|6874975_6878719_+|tetratricopeptide-repeat-protein
MDNKRIEAYTNLVNQLLTSPSGEKAKILETNLDLVDEGLLEIMELYAQQLAENDDENAQNAANFLRHLRSQLVELLETSEFSPSTHYSSAEYLNFWREVLLATAESKGDPKVVYPLLQENLDKLDDNFADILRNWATAKFSEVEAGVAKSIAIDIIYFSVYIKQFPLGSKANNMEISIAGYEVVLKVFTYKSHREIWAMTQNNLGAAYSDRIRGDKAENIEAAIAAYQQALLVYTQTDFPMDWAMTQNNLGNAYSDRIRGNKAENIEAAIAAYEQALLVYTQTDFPMDWARTQNNLGIAYSNRIRGDKAENIEAAIAAFQQALLVYTQTDFPMEWARTQNNLGIAYSNRIRGDKAENIEAAIAACQQALLVRTQTDFPINWAATQNNLGAAYRDRIRGDKAENIEAAIAACQQALLVYTQTDFPINWARTQNNLGIAYSDRIRGDKAENIEAAIAAYQQALLVRTQTDFPINWATIQNNLGAAYRDRIRGDKAENIEAAIAAYEQALLVRTQTDFPMDWARTQNNLGNAYSDRIRGDKAENIEAAIAAYQQALLVRTQTDFPMDWAMTQNNLGNAYSDRIRGDKAENIEAAIAAYQQALLVRTQTDFPMDWAGTQNNLGNAYSDRIRGDKAENIEAAIAAYEQALLVYTLEADPIKHLGTTRNLGNLYFDNQNWQLAADNYKKAITAVELSRSWATTDDRRQEILKENINIYNKAIQAYIHLKKLEQALEIAERSQARNLVQLLTNRDLVPQDNVPPEITQQLQQQQKEIRVNKGELEKVRKQLSQQNTEEKTSLEKSEKQLNEELQKLRQQLEKTFNQIQEYDPTFRLTQEVQPIAFREIQQLATEQQTAIIEWYIMGEKFLAFILVPPTSTATSELFMWQSTEDDSKNLEEWVKEYLEKYYELQEAELENQEKAKKLQQEWETKITTRLEKLGEILHIKEILQPILESECQRLTLIPHSFLHFLPLHILPINNPENSQENPEKKYLQDYFNQGVSYAPSCQILQKVRERKNQEFQSLFAIQNLNDTENSPHLGIISIIKKQFNNVEIIQENQATKSALINHPKLSLANSILFFCHGVFNPTYPLDSGLILADEKLTLGDIIQNLNLSKCRLVTLAACETGLTDIFNQEYVGLPSGFLLAGSTNIIASLWSVRVDATALLMLRLYQELKKYDNIIIALKTAQNWLRDIKVQELKEWVRKSPLKIKIHWQEELEKTFTKMENLEGANCKPYNSPYFWAGFCVVGKGE
>NC_008312.1|WP_044137913.1|6879043_6879688_-|5,6-dimethylbenzimidazole-synthase
MKGRAFTEQESQVLADIIINRRTEFGKNFISKEIPDSIVERLLSAALHAPSVGFSQPWEFIIIRDPLIKAKVKDSFIKENEKAKKIFKDRPFYNQLQLEGITAAPVNIAVFYKPSPNSVVGQTSQEKFGPYSVCLAIQNLWLMARAENLGLGWVSILDEKEVKMILNAPLENELIAYLCIGYVTEFTERPLLEITNWEKRKLKESIIYYDGYQN
>NC_008312.1|WP_011613772.1|6880578_6882291_+|bifunctional-3,4-dihydroxy-2-butanone-4-phosphate-synthase-RibB/GTP-cyclohydrolase-II-RibA
MNKQQNQKFKFDPIDTALADIKAGKCVVVVDDEHRENEGDVICAAQFATPNMINFMAVKARGLICLALTGDRLDQLEVPLMVTNNTDSNQTAFTVSIDASPELGVSTGISAEDRARTIQAVINSNTKPEDLRRPGHVFPIRAKEGGVLKRAGHTEASIDLARLSGLYPAGVICEIQNPDGSMARLPQLVEYAQTHNLKLISIADIISYRIKHDRFVFREAVAKLPSQFGNFQIYAYRDTQNNLEHIAIVKGNPAEFSQRDIMVRVHSECLTGDAFGSLRCDCRMQLQAAMKMIEHAGAGVVVYLRQEGRGIGLVNKLKAYSLQDIGLDTVEANERLGFPADLRNYGVGAQILHDLGVNKMRLITNNPRKIAGLHGYGIEIVDRVPLLIETTDYNSAYLATKAQKLGHILLRSYLVTIAINWNNQKIEEETFDNSDHINMKSLAQQRYQYLEKLRSLIKEYDFLLQEETRPVATAVFAQAPLIVNFGLEQATLTTSKWYQESNNPYLVAIAKVLTEIAQWQNMLKLEFIIASGLDPMIALQIKLERQTLEITELSTAMEHLETQKIYSLKI
>NC_008312.1|WP_011613773.1|6882817_6883072_+|TIGR03643-family-protein
MKIPDLDNQNIDRIVEMAWEDRTPFEAIKTQFGLEEKQVIVLMRRSMSISSFKMWRKRVTGRKTKHTHKRAFELGRFKSKNQKS
>NC_008312.1|WP_011613774.1|6883491_6885699_+|DUF839-domain-containing-protein
MNIKRREFLIFLGAGAGKIVLSSSQQEPSAKLAKKYPINNSSTNNINFQPPQSPIPLVTSNQEFKIDDYTTYEVVDDLVIPKGFTYDIIASWGDKIGDSRFGYNNDYLSYIETGENEGLLTINFEYISPLPWVTSYQKIIGKSLPFLEIASEFQEAVKSNINSQELLNKSPLKKQITTIAKEAMIDMGIGVISIRRQPDGQWVRTNSKFDRRITGISGLEDGHYLKSTGPAVAVFKKKGKGYDDKLGDRIIGSFANCAGGTTPWGTVFSAEENFQKYVIEAVYSDGTSIDPTQDKSLFIGEQGVVGLGSAFGLAGNKYGWMVEVDPALPDDYGTKHTWLGRYRHEAVGIRAQANQPLAFYSGCDRRSGHLYKFVSKDIVKDPTDKSNSQLLTNGMLYGAKFNSNGTGSWIPLKEDTPVNPDLPSVHVNNMINLPQRPDGGSFKVTKDRDIEAFKQKYQTLGDLYQGDPEAKQGAILIDAHLAGNAAGVTCTARPEDTIVAKDGSLFIAFTSGYPSSSDGSPDQRIFKGPDGEAYEYGWIMRLVEDSDRPDAMTFRWQMFATGGEPTFGGLGFSNPDNLEFDDQGNLWMVTDISTNKHNQIVPENRIDKDGKPINQASLCGLFGNNSIWYIPTSGSNAGQAYLFGIGPTESETSGPFFTKDGETLFLAIQHPGEYNGIRQNMASETRRLAMKTIDGSDFMQNRIVPMGSNWPEKKINHPPKPSVVAIRRLDSTRIT

Crispr_ID: NC_008312_46

• CRISPR_ID: NC_008312_46
• CRISPR_location: 7020732-7020890
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NC_008312_46

Consensus_repeat	Method
TATTGGTGCGTTTTCTGCTGAAGTTTGTCTTGCTCAGAGGTTTATCGGGAGG	CRISPRCasFinder

spacers of NC_008312_46

>46.1|7020784|55|NC_008312|CRISPRCasFinder
GGAGCACTAAATAAATAAAGCGCAATAGTTAATATCTTCTGTTTGAGACTGAAAG

CRISPR arrays and Neighbor proteins around NC_008312_46

CRISPR arrays

The CRISPR arrays of NC_008312_46

>merge|NC_008312|46|7020732-7020890|CRISPRCasFinder
TATTGGTGCGTTTTCTGCTGAAGTTTGTCTTGCTCAGAGGTTTATCGGGAGGGGAGCACTAAATAAATAAAGCGCAATAGTTAATATCTTCTGTTTGAGACTGAAAGTATTGGTGCGTTTTCTGCTGAAGTTTGTCTTGGTCAGAGGTTTATCGGGAGG

>NC_008312|46|36|7020732-7020890|CRISPRCasFinder
TATTGGTGCGTTTTCTGCTGAAGTTTGTCTTGCTCAGAGGTTTATCGGGAGG	GGAGCACTAAATAAATAAAGCGCAATAGTTAATATCTTCTGTTTGAGACTGAAAG
TATTGGTGCGTTTTCTGCTGAAGTTTGTCTTGGTCAGAGGTTTATCGGGAGG

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_008312.1|WP_155994444.1|7017919_7018156_+|hypothetical-protein	unknown	unknown	unknown
NC_008312.1|WP_155994575.1|7018534_7018771_-|hypothetical-protein	unknown	unknown	gnl|CDD|315923
NC_008312.1|WP_044137934.1|7024322_7025321_-|family-10-glycosylhydrolase	unknown	unknown	gnl|CDD|224563
NC_008312.1|WP_155994576.1|7019124_7019301_-|hypothetical-protein	unknown	unknown	unknown
NC_008312.1|WP_011613862.1|7028525_7029737_-|N-acetyltransferase	unknown	unknown	gnl|CDD|377314
NC_008312.1|WP_155994574.1|7017384_7017852_-|DDE-transposase-family-protein	unknown	unknown	gnl|CDD|372649
NC_008312.1|WP_011613865.1|7033112_7036100_+|peptidoglycan-DD-metalloendopeptidase-family-protein	unknown	unknown	gnl|CDD|366703
NC_008312.1|WP_044136462.1|7020176_7020560_+|transposase	unknown	unknown	gnl|CDD|372577
NC_008312.1|WP_044136462.1|7016955_7017339_-|transposase	unknown	unknown	gnl|CDD|372577
NC_008312.1|WP_155994573.1|7016661_7016805_-|hypothetical-protein	unknown	unknown	unknown
NC_008312.1|WP_011613860.1|7025684_7026989_-|homoserine-dehydrogenase	unknown	unknown	gnl|CDD|235783
NC_008312.1|WP_155994577.1|7036096_7036291_-|hypothetical-protein	unknown	unknown	unknown
NC_008312.1|WP_044137936.1|7030420_7031758_-|cytosine-deaminase	unknown	unknown	gnl|CDD|236062
NC_008312.1|WP_011609970.1|7015728_7016415_-|transposase	unknown	unknown	unknown
NC_008312.1|WP_011613864.1|7031876_7032635_+|DUF561-domain-containing-protein	unknown	unknown	gnl|CDD|113257
NC_008312.1|WP_044137940.1|7037038_7037860_-|hypothetical-protein	unknown	unknown	gnl|CDD|227078
NC_008312.1|WP_011613851.1|7018842_7018986_-|hypothetical-protein	unknown	unknown	gnl|CDD|315923
NC_008312.1|WP_052845856.1|7036615_7036825_-|hypothetical-protein	unknown	unknown	unknown
NC_008312.1|WP_011613857.1|7022660_7022981_-|transposase	unknown	unknown	gnl|CDD|379129
NC_008312.1|WP_081432502.1|7016411_7016705_-|hypothetical-protein	unknown	unknown	gnl|CDD|379252

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_008312.1|WP_155994575.1|7018534_7018771_-|hypothetical-protein	gnl|CDD|315923	pfam13358, DDE_3, DDE superfamily endonuclease. This family of proteins are related to pfam00665 and are probably endonucleases of the DDE superfamily. Transposase proteins are necessary for efficient DNA transposition. This domain is a member of the DDE superfamily, which contain three carboxylate residues that are believed to be responsible for coordinating metal ions needed for catalysis. The catalytic activity of this enzyme involves DNA cleavage at a specific site followed by a strand transfer reaction.	3.37672e-21
NC_008312.1|WP_011613860.1|7025684_7026989_-|homoserine-dehydrogenase	gnl|CDD|235783	PRK06349, PRK06349, homoserine dehydrogenase; Provisional.	0
NC_008312.1|WP_011613862.1|7028525_7029737_-|N-acetyltransferase	gnl|CDD|377314	pfam04339, FemAB_like, Peptidogalycan biosysnthesis/recognition. FemAB_like is a family of both baterial and Viridiplantae proteins with responsibility for building interpeptide bridges in peptidoglycan. Such a function is feasible for bacteria but less likely for the plant members of this family. Perhaps the plant-members are using homologous proteins to recognize bacterial peptidoglcans as part of their innate immune system.	0
NC_008312.1|WP_155994574.1|7017384_7017852_-|DDE-transposase-family-protein	gnl|CDD|372649	pfam13613, HTH_Tnp_4, Helix-turn-helix of DDE superfamily endonuclease. This domain is the probable DNA-binding region of transposase enzymes, necessary for efficient DNA transposition. Most of the members derive from the IS superfamily IS5 and rather fewer from IS4.	3.47053e-18
NC_008312.1|WP_011613865.1|7033112_7036100_+|peptidoglycan-DD-metalloendopeptidase-family-protein	gnl|CDD|366703	pfam01551, Peptidase_M23, Peptidase family M23. Members of this family are zinc metallopeptidases with a range of specificities. The peptidase family M23 is included in this family, these are Gly-Gly endopeptidases. Peptidase family M23 are also endopeptidases. This family also includes some bacterial lipoproteins for which no proteolytic activity has been demonstrated. This family also includes leukocyte cell-derived chemotaxin 2 (LECT2) proteins. LECT2 is a liver-specific protein which is thought to be linked to hepatocyte growth although the exact function of this protein is unknown.	1.04035e-21
NC_008312.1|WP_044136462.1|7020176_7020560_+|transposase	gnl|CDD|372577	pfam13359, DDE_Tnp_4, DDE superfamily endonuclease. This family of proteins are related to pfam00665 and are probably endonucleases of the DDE superfamily. Transposase proteins are necessary for efficient DNA transposition. This domain is a member of the DDE superfamily, which contain three carboxylate residues that are believed to be responsible for coordinating metal ions needed for catalysis. The catalytic activity of this enzyme involves DNA cleavage at a specific site followed by a strand transfer reaction.	3.02011e-23
NC_008312.1|WP_044137934.1|7024322_7025321_-|family-10-glycosylhydrolase	gnl|CDD|224563	COG1649, COG1649, Uncharacterized protein conserved in bacteria [Function unknown].	3.40506e-36
NC_008312.1|WP_044137940.1|7037038_7037860_-|hypothetical-protein	gnl|CDD|227078	COG4735, COG4735, Uncharacterized protein conserved in bacteria [Function unknown].	2.08927e-61
NC_008312.1|WP_081432502.1|7016411_7016705_-|hypothetical-protein	gnl|CDD|379252	pfam13546, DDE_5, DDE superfamily endonuclease. This family of proteins are related to pfam00665 and are probably endonucleases of the DDE superfamily. Transposase proteins are necessary for efficient DNA transposition. This domain is a member of the DDE superfamily, which contain three carboxylate residues that are believed to be responsible for coordinating metal ions needed for catalysis. The catalytic activity of this enzyme involves DNA cleavage at a specific site followed by a strand transfer reaction.	2.94792e-14
NC_008312.1|WP_044137936.1|7030420_7031758_-|cytosine-deaminase	gnl|CDD|236062	PRK07583, PRK07583, cytosine deaminase.	0
NC_008312.1|WP_011613864.1|7031876_7032635_+|DUF561-domain-containing-protein	gnl|CDD|113257	pfam04481, DUF561, Protein of unknown function (DUF561). Protein of unknown function found in a cyanobacterium, and the chloroplasts of algae.	1.12078e-98
NC_008312.1|WP_011613851.1|7018842_7018986_-|hypothetical-protein	gnl|CDD|315923	pfam13358, DDE_3, DDE superfamily endonuclease. This family of proteins are related to pfam00665 and are probably endonucleases of the DDE superfamily. Transposase proteins are necessary for efficient DNA transposition. This domain is a member of the DDE superfamily, which contain three carboxylate residues that are believed to be responsible for coordinating metal ions needed for catalysis. The catalytic activity of this enzyme involves DNA cleavage at a specific site followed by a strand transfer reaction.	0.00218956
NC_008312.1|WP_011613857.1|7022660_7022981_-|transposase	gnl|CDD|379129	pfam13340, DUF4096, Putative transposase of IS4/5 family (DUF4096).	3.45265e-28
NC_008312.1|WP_044136462.1|7016955_7017339_-|transposase	gnl|CDD|372577	pfam13359, DDE_Tnp_4, DDE superfamily endonuclease. This family of proteins are related to pfam00665 and are probably endonucleases of the DDE superfamily. Transposase proteins are necessary for efficient DNA transposition. This domain is a member of the DDE superfamily, which contain three carboxylate residues that are believed to be responsible for coordinating metal ions needed for catalysis. The catalytic activity of this enzyme involves DNA cleavage at a specific site followed by a strand transfer reaction.	3.02011e-23

Protein sequences

>NC_008312.1|WP_044136462.1|7020176_7020560_+|transposase
MITTPKGTEIVDVIVGEKGPVSDVKILRKQQDKFDKKQKFQGDKAYEGVERTTTPKKKPRKKEMPLEIKEENQEKARKRIFVEHVIRLIKIFGIARERFRLKDNNYQKVILTICGLVRLRIGSFILA
>NC_008312.1|WP_155994576.1|7019124_7019301_-|hypothetical-protein
MSISLMSGLLNISRPTLHQWREIYLTTGSTTQSANIPPPQTSKIKNWEECEKFVEDTK
>NC_008312.1|WP_011613851.1|7018842_7018986_-|hypothetical-protein
MALKLNQIDKKDIVYVDEAGIDNREDYPYGYGFKGIHSTRHEVRKKN
>NC_008312.1|WP_155994575.1|7018534_7018771_-|hypothetical-protein
MVTCLRTGWKIVPIPKLQPGQVIILDNTTFHKSVYIEELVAKQRCEIWYLPPYSPDFNKIERWWFVLKNDLQTKTEEI
>NC_008312.1|WP_155994444.1|7017919_7018156_+|hypothetical-protein
MLELENAVICGTCDLQCCWQFETSFFDRFLKSNPPIYSLNPVFWAFVLKTLLKRSHHRWKQEGMATEVVSFIKLFPGQ
>NC_008312.1|WP_155994574.1|7017384_7017852_-|DDE-transposase-family-protein
MNPTLEYIYNHPKETKRIIGITYEQLIKLIAKAQIIESEKKKAIAKTEKRLIKAGGVRKKNLTKEEEIILTLFYLHQIPTFQTLGINFGISESSANNIFHYWIDILRELLPASLLEQVKKKENELEWVKEILTELELIVDSTEQSRERPSEYKDQ
>NC_008312.1|WP_044136462.1|7016955_7017339_-|transposase
MITTPKGTEIVDVIVGEKGPVSDVKILRKQQDKFDKKQKFQGDKAYEGVERTTTPKKKPRKKEMPLEIKEENQEKARKRIFVEHVIRLIKIFGIARERFRLKDNNYQKVILTICGLVRLRIGSFILA
>NC_008312.1|WP_155994573.1|7016661_7016805_-|hypothetical-protein
MSIFGDVYWSVDAVNERRLQVMWERRQTKPSRSYCFNYRRFRPQKKW
>NC_008312.1|WP_081432502.1|7016411_7016705_-|hypothetical-protein
MALIIDDSGHRKSGNFTAGVGRQYIGEIGKTDNGVVVVTTHLYDGVKSLPLDIALYQKADSFPKGKKDPEFVKKPDECNVSSRSMFVQRTPTRNCVN
>NC_008312.1|WP_011609970.1|7015728_7016415_-|transposase
MKFGYGNNTSFLNQLEKRSLTYIGGLAKNRKVIIKKQDDIKEEIRLDKLAESIPQKAFNLVQLSTKNAREVWVATLEVEISRMSGQKTIAIVMNAKSFSEATDINYYITNREDKYVTPEWIYSTYSQRNWVEVFYREAKGWLGLREYQVRDKISLKRHFILVFCAYTFIIWHQLTGGIRRRWANKPLNTFTDTLEAFRTAISYRFVEWLDENIDVFTAHKESLGFVWA
>NC_008312.1|WP_011613857.1|7022660_7022981_-|transposase
MTYSSCLTDPEWEIVEPLLLELLPPKKQTRPPDWTKREILDGIFYQLKNGCNWGDLPKELPPYSTVYWYYKQWRDAGVIEKLMDALHPRVRQQVKKKALRDNLDHH
>NC_008312.1|WP_044137934.1|7024322_7025321_-|family-10-glycosylhydrolase
MIKKFLRWLSILIGVCLLLVVTHHASPRSPVVKDKMQGIWLTNIATAFLHHTTYLDEILHQLSISGYDRVYFSVYGFKGTLYPTSHSSTYFLLRPPLTNPLKAAVQESRRQGLKPYAWFEYGLMLYPKNAIVKKHPDWLLKTGEGEIVEDGNVWLDPTHREVQEYILGHIDDILKIKGLAGIQLDDHWAVPKAFGNINQRQALTSLTQKVYNHIKAKNPQLVVSISPNPYHFAVSRYNQDWLWWVKQKIVDEVVLQIYRPTPEAVVASLSNSGIYTASYYMPVGVGISATWNVVPFSLNTVQKQVAAVKQQGYGYSIFSWEYLVLRRLAQFF
>NC_008312.1|WP_011613860.1|7025684_7026989_-|homoserine-dehydrogenase
MVFKIGLLGLGTVGIGTAKILLSPQGRHPLINELEIYRVGVRDISKTRDINISPNILTTDLEAIATDPDVDIIIELIGGLEPARSLILKAIEHGKHIVTANKAVISRYGPEIFDAANKKSVYVMLEASVGGGIPVIQPLKESLTVNRIHSITGIINGTTNYILTKMQKEGADFADVLADAQKLGYAEANPTADVEGLDAKDKIAILGSLAFSGFIKLEDIYCEGIRQITAADITYAAQLNFVIKLLAIAKQAPKNTNFTSDKLQLRVHPTLIPKTHPLASINDVDNAIFIEGEPIGQVMFFGPGAGAGPTASAVVSDIMNIAAILQTETEPIPHPLLSCTHQKYCEIVPIKELITRFYARFLTQDKPGVIGKLGSCFGKYSVSLESVVQTGIHNQLAEIVVVTRDVREGNFRQALEEIQSLDVINSIPSILRVL
>NC_008312.1|WP_011613862.1|7028525_7029737_-|N-acetyltransferase
MIQQPKPQYSIAWISKIAEVPKPEWDALAQPLKTPFLEWDWLHNMEKSGSVGGRSGWLPQHLTVWRDRQLIAAAPLYLKGHSQGEFVFDHQWAEISYRLGIEYYPKLLGMSPFTPAEGYRFLIASGEDEDEITAMMVSEIDYFCDRHNISGCHFLYVDPEWHPIIKRNGFTNWLHHSYIWQNQGYQTFDDYLKVFNANQRRNIKRERKAVGKAGLQMQTLTGDEISKALCSKMYNFYESTCDKFGWWGSKYLTRRFFEQLHHNFRHRVLFVAGYSEENDRFPVGMSFCITKGDRLYGRYWGSNYEIDCLHFDACYYTPIEWAIQNGIKSFDPGAGGRHKKRRGFPATPNHSMHRFYHNRLSKIFLSYIGQVNEMEQLEMERINEDLPFIQGVGNLEEKSGGAS
>NC_008312.1|WP_044137936.1|7030420_7031758_-|cytosine-deaminase
MNHQQFSVMPETSNYWLKNAHVPACLIERELEISDQTRVGLSLVDIEIKEGVITQIVHSLADLPSLNNGDIPRVDLKGGMVWPCFVDMHTHLDKGHIWERSPNPDGSFNGALDAGARDGEKYWNAEDIYRRMEFGLKCSYAHGTKAIRTHLDCFAQQANISLEVFQTLQKKWESRLILQPVSLVTGDYYLTEAGEKLADQIADIGGILGGVPFINSDLDNQLDRLFSIAKERQLDLDLHTDENGDPNSRVLHKVAEKAISHQFYGKIICGHCCSLAVQTPEKVTETIKLVKEAGISIVSLPMCNLYLQNRQENYTPRWRGVTLLHELKKQGISVAIASDNCRDPFFGFGDHDVLEVFNMSVRIAHLDMPYGDWPCAVTKTPGDLIGLPNVGIIKVGLPADLILFKGRNFSELLSRSQHDRVVLRNGLVIDTTLPDYSELDSLFYG
>NC_008312.1|WP_011613864.1|7031876_7032635_+|DUF561-domain-containing-protein
MITESRLQSALKNGQALKVISGLTNFDRDRVAATVKAATLGGATFLDIAADPNLVEMARSLTNLPICVSAIEAAKFVPAVKAGADLIEIGNYEAFYAQGMRFEAEEVLRLTQETRDLLPNITLSVTVPHILELDRQVQLATELVKAGADIIQTEGAVSAQPIHPGTLGLIEKAAPTLAAAYEISRAVDIPVLCASGISNVTAPLAIAAGAAGVGVGSAINRLNDEVAMIAAVRSLVEALANVSHIKVGSMSI
>NC_008312.1|WP_011613865.1|7033112_7036100_+|peptidoglycan-DD-metalloendopeptidase-family-protein
MSDILGDFSNFEQDLSNLILIGDKQENFDDGQRWTSGIEPTGNNSKLKVEEFNTGGDEPSQPLQGQKFFDLGELNHLSASNSPPGKKDPLVGEDNEAVVKKSDNLINPNPINRRSGNSRNRADNIGTLSSSSSFTGFVGTTDTNDYYRFYLSGEREFNLTLNGLSGDADVRLLNSSGGTISSSTKGGSSSESISETLNSGTYYIRVYPMSGVNTNYNLNIEATSSSSDEEVNITSPSSRTSIEPGERYNIRWTDNFRDNVKLELYKGSSRQQTIARSTSSDGSYSWRAPTSLSSGTNYRIKIRNVNDSSVYDYSSYFTIEPDEPDGVVNITSPSSSTSIEPGERYNIRWTDNFRDNVKLELYKGSSRQQTIARSTSSDGSYSWRAPTSLSSGTNYRIKIRNVNDSSVYDYSSYFTIEPDEPDEKVNITSPSSSTSIEPGERYNIRWTDNFRDNVKLELYKGSSRQRTIARSTSSDGSYSWRAPTSLSSGTNYRIKIRNVNDSSVYDYSSYFTIKPDEEVNITSPSSSTSIEPGESYTIRWTDNFSDNVKLDLYKGSSWQQTIASSTSSDGSYSWRVPTSLSSGTNYNIKIRNVNDSSVDDYSNSFTIQSTTWPPSVTKDLKTYTGREEYSGYVGNDDYYKFSVDSPGYLQFALRGMSADANLQLLNSSGKVLESSSKSGNSDEYANENLGIGTYYMRVYGHNGADTNYRLVLNLDKAKNDRSNARWLGELAGQRKEYKDFIGTSSGDQYDYYKFTVQEPRFLEYALRDLTAPADIDILNSSGARITPKENDKDNHRYNLHETMGLQAGTYYARVTAPTDSSQQTNYKLVLNLKGEYKPLHSNPTESNPLKGFQSPVRGERWYVSQSPGGSYSHTGNLRYAIDISIPGWDDFGEPIYAMRSGTVKKVVDDHPDIADSKRNNLVEIQHENGYVARYWHLQQYSNSDAGLQVGQKVDAGQMIGRVGNSGFSTGPHLHVDVVDSSLITRPFEIEGIFDY
>NC_008312.1|WP_155994577.1|7036096_7036291_-|hypothetical-protein
MAWEERSLWGNYKVNHSSRDIGRAIISSIYRIVITCSRNGAVWRQMRQHLCSMEFDRQKCHLRV
>NC_008312.1|WP_052845856.1|7036615_7036825_-|hypothetical-protein
MIADQTLQFREVWIDPACSLLYLFLWLGTSDGRFEPAEGYGLILKKDNYDEAQFLWLENEYEADLKLWS
>NC_008312.1|WP_044137940.1|7037038_7037860_-|hypothetical-protein
MNELRAVLELATEEELQQLTELLFGRGINPLDYFQTPLPIDVQSRDRHVWLDALDQRFRYLAADGMTVLRGKTQKVTYRQVLIKVCDYLKIPYSQKLSTTDLEAEVFLNVLGRTWKRLPRSERNVLRKNIQSSLAQCNFPQPLPKLIQNNPLSLLFKGGIACAVTSVLKPILLKQLARQFAIHFAKYQMAKAALVRGGAAGVTQFQGHVAMQMANRGMAISTARYGALRTALGILGPMLWTWFLADLGWRAIATNYGRVVPAVFVLAQIRLLN

Crispr_ID: NC_008312_47

• CRISPR_ID: NC_008312_47
• CRISPR_location: 7278240-7278341
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NC_008312_47

Consensus_repeat	Method
TCTGCAACTATGGATAAAAAAACTTCTAAATTATTA	CRISPRCasFinder

spacers of NC_008312_47

>47.1|7278276|30|NC_008312|CRISPRCasFinder
TTTATCAATTCTAAATTCTCATTATTATTG

CRISPR arrays and Neighbor proteins around NC_008312_47

CRISPR arrays

The CRISPR arrays of NC_008312_47

>merge|NC_008312|47|7278240-7278341|CRISPRCasFinder
TCTGCAACTATGGATAAAAAAACTTCTAAATTATTATTTATCAATTCTAAATTCTCATTATTATTGTCTGCAACTATGGATTAAAAAAACTTCTAAATTATT

>NC_008312|47|37|7278240-7278341|CRISPRCasFinder
TCTGCAACTATGGATAAAAAAACTTCTAAATTATTA	TTTATCAATTCTAAATTCTCATTATTATTG
TCTGCAACTATGGATTAAAAAAACTTCTAAATTATT

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_008312.1|WP_011614025.1|7302433_7303252_-|inositol-monophosphatase	unknown	unknown	gnl|CDD|238821
NC_008312.1|WP_081432505.1|7288917_7289178_-|hypothetical-protein	unknown	unknown	gnl|CDD|372577
NC_008312.1|WP_011614026.1|7305069_7305693_-|DUF938-domain-containing-protein	unknown	unknown	gnl|CDD|253548
NC_008312.1|WP_081432519.1|7265800_7266256_-|IS630-family-transposase	unknown	unknown	gnl|CDD|315923
NC_008312.1|WP_155994742.1|7280858_7282022_-|DUF4336-domain-containing-protein	unknown	unknown	gnl|CDD|372974
NC_008312.1|WP_011614016.1|7277651_7278023_+|hypothetical-protein	unknown	unknown	unknown
NC_008312.1|WP_011614020.1|7284209_7286588_-|CBS-domain-containing-protein	unknown	unknown	gnl|CDD|341389
NC_008312.1|WP_011614011.1|7265338_7265716_+|hypothetical-protein	unknown	unknown	gnl|CDD|379315
NC_008312.1|WP_044137031.1|7276609_7276858_+|(2Fe-2S)-ferredoxin-domain-containing-protein	unknown	unknown	gnl|CDD|239278
NC_008312.1|WP_081432519.1|7269189_7269645_+|IS630-family-transposase	unknown	unknown	gnl|CDD|315923
NC_008312.1|WP_011614010.1|7263601_7263862_-|hypothetical-protein	unknown	unknown	unknown
NC_008312.1|WP_011611074.1|7266264_7266768_-|helix-turn-helix-domain-containing-protein	unknown	unknown	gnl|CDD|379267
NC_008312.1|WP_011614024.1|7290401_7300685_+|DUF4347-domain-containing-protein	unknown	unknown	gnl|CDD|270410
NC_008312.1|WP_011614017.1|7278919_7279090_-|hypothetical-protein	unknown	unknown	unknown
NC_008312.1|WP_011611074.1|7268677_7269181_+|helix-turn-helix-domain-containing-protein	unknown	unknown	gnl|CDD|379267
NC_008312.1|WP_011614027.1|7307140_7307290_+|hypothetical-protein	unknown	unknown	unknown
NC_008312.1|WP_011614018.1|7279224_7280568_+|glutathione-disulfide-reductase	unknown	unknown	gnl|CDD|235701
NC_008312.1|WP_011614013.1|7273366_7274410_+|sirohydrochlorin-chelatase	unknown	unknown	gnl|CDD|225049
NC_008312.1|WP_044137032.1|7283270_7283465_-|hypothetical-protein	unknown	unknown	unknown
NC_008312.1|WP_011614014.1|7275613_7276594_+|cysteine-synthase-A	unknown	unknown	gnl|CDD|182672

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_008312.1|WP_081432505.1|7288917_7289178_-|hypothetical-protein	gnl|CDD|372577	pfam13359, DDE_Tnp_4, DDE superfamily endonuclease. This family of proteins are related to pfam00665 and are probably endonucleases of the DDE superfamily. Transposase proteins are necessary for efficient DNA transposition. This domain is a member of the DDE superfamily, which contain three carboxylate residues that are believed to be responsible for coordinating metal ions needed for catalysis. The catalytic activity of this enzyme involves DNA cleavage at a specific site followed by a strand transfer reaction.	1.58528e-06
NC_008312.1|WP_011614026.1|7305069_7305693_-|DUF938-domain-containing-protein	gnl|CDD|253548	pfam06080, DUF938, Protein of unknown function (DUF938). This family consists of several hypothetical proteins from both prokaryotes and eukaryotes. The function of this family is unknown.	1.53264e-90
NC_008312.1|WP_081432519.1|7265800_7266256_-|IS630-family-transposase	gnl|CDD|315923	pfam13358, DDE_3, DDE superfamily endonuclease. This family of proteins are related to pfam00665 and are probably endonucleases of the DDE superfamily. Transposase proteins are necessary for efficient DNA transposition. This domain is a member of the DDE superfamily, which contain three carboxylate residues that are believed to be responsible for coordinating metal ions needed for catalysis. The catalytic activity of this enzyme involves DNA cleavage at a specific site followed by a strand transfer reaction.	3.80024e-17
NC_008312.1|WP_155994742.1|7280858_7282022_-|DUF4336-domain-containing-protein	gnl|CDD|372974	pfam14234, DUF4336, Domain of unknown function (DUF4336).	0
NC_008312.1|WP_011614011.1|7265338_7265716_+|hypothetical-protein	gnl|CDD|379315	pfam13655, RVT_N, N-terminal domain of reverse transcriptase. This domain is found at the N-terminus of bacterial reverse transcriptases.	1.65646e-45
NC_008312.1|WP_044137031.1|7276609_7276858_+|(2Fe-2S)-ferredoxin-domain-containing-protein	gnl|CDD|239278	cd02980, TRX_Fd_family, Thioredoxin (TRX)-like [2Fe-2S] Ferredoxin (Fd) family; composed of [2Fe-2S] Fds with a TRX fold (TRX-like Fds) and proteins containing domains similar to TRX-like Fd including formate dehydrogenases, NAD-reducing hydrogenases and the subunit E of NADH:ubiquinone oxidoreductase (NuoE). TRX-like Fds are soluble low-potential electron carriers containing a single [2Fe-2S] cluster. The exact role of TRX-like Fd is still unclear. It has been suggested that it may be involved in nitrogen fixation. Its homologous domains in large redox enzymes (such as Nuo and hydrogenases) function as electron carriers.	2.12741e-18
NC_008312.1|WP_011614014.1|7275613_7276594_+|cysteine-synthase-A	gnl|CDD|182672	PRK10717, PRK10717, cysteine synthase A; Provisional.	0
NC_008312.1|WP_011614025.1|7302433_7303252_-|inositol-monophosphatase	gnl|CDD|238821	cd01643, Bacterial_IMPase_like_2, Bacterial family of Mg++ dependent phosphatases, related to inositol monophosphatases. These enzymes may dephosphorylate inositol monophosphate or similar substrates.	1.09028e-113
NC_008312.1|WP_011611074.1|7266264_7266768_-|helix-turn-helix-domain-containing-protein	gnl|CDD|379267	pfam13565, HTH_32, Homeodomain-like domain.	1.3107e-10
NC_008312.1|WP_011614024.1|7290401_7300685_+|DUF4347-domain-containing-protein	gnl|CDD|270410	cd13692, PBP2_BztA, Substrate bindng domain of ABC glutamate/glutamine/aspartate/asparagine transporter; the type 2 periplasmic binding protein fold. BztA is the periplamic-binding protein component of ABC transporter specific for carboxylic amino acids, glutamine and asparagine. The BZtA domain belongs to the type 2 periplasmic binding protein fold superfamily (PBP2), whose many members are involved in chemotaxis and uptake of nutrients and other small molecules from the extracellular space as a primary receptor. The PBP2 proteins are typically comprised of two globular subdomains connected by a flexible hinge and bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap. After binding their specific ligand with high affinity, they can interact with a cognate membrane transport complex comprised of two integral membrane domains and two receptor cytoplasmically-located ATPase domains. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis.	2.33728e-90
NC_008312.1|WP_081432519.1|7269189_7269645_+|IS630-family-transposase	gnl|CDD|315923	pfam13358, DDE_3, DDE superfamily endonuclease. This family of proteins are related to pfam00665 and are probably endonucleases of the DDE superfamily. Transposase proteins are necessary for efficient DNA transposition. This domain is a member of the DDE superfamily, which contain three carboxylate residues that are believed to be responsible for coordinating metal ions needed for catalysis. The catalytic activity of this enzyme involves DNA cleavage at a specific site followed by a strand transfer reaction.	3.80024e-17
NC_008312.1|WP_011611074.1|7268677_7269181_+|helix-turn-helix-domain-containing-protein	gnl|CDD|379267	pfam13565, HTH_32, Homeodomain-like domain.	1.3107e-10
NC_008312.1|WP_011614018.1|7279224_7280568_+|glutathione-disulfide-reductase	gnl|CDD|235701	PRK06116, PRK06116, glutathione reductase; Validated.	0
NC_008312.1|WP_011614013.1|7273366_7274410_+|sirohydrochlorin-chelatase	gnl|CDD|225049	COG2138, COG2138, Sirohydrochlorin ferrochelatase [Inorganic ion transport and metabolism].	1.56094e-70
NC_008312.1|WP_011614020.1|7284209_7286588_-|CBS-domain-containing-protein	gnl|CDD|341389	cd04620, CBS_two-component_sensor_histidine_kinase_repeat1, 2 tandem repeats of the CBS domain in the two-component sensor histidine kinase and related-proteins, repeat 1. This cd contains 2 tandem repeats of the CBS domain in the two-component sensor histidine kinase and related-proteins. Two-component regulation is the predominant form of signal recognition and response coupling mechanism used by bacteria to sense and respond to diverse environmental stresses and cues ranging from common environmental stimuli to host signals recognized by pathogens and bacterial cell-cell communication signals. The structures of both sensors and regulators are modular, and numerous variations in domain architecture and composition have evolved to tailor to specific needs in signal perception and signal transduction. The simplest histidine kinase sensors consists of only sensing and kinase domains. The more complex hybrid sensors contain an additional REC domain typical of two-component regulators and in some cases a C-terminal histidine phosphotransferase (HPT) domain. The CBS domain, named after human CBS, is a small domain originally identified in cystathionine beta-synthase and is subsequently found in a wide range of different proteins. CBS domains usually occur in tandem repeats. They associate to form a so-called Bateman domain or a CBS pair based on crystallographic studies in bacteria. The CBS pair was used as a basis for this cd hierarchy since the human CBS proteins can adopt the typical core structure and form an intramolecular CBS pair. The interface between the two CBS domains forms a cleft that is a potential ligand binding site. The CBS pair coexists with a variety of other functional domains and this has been used to help in its classification here. It has been proposed that the CBS domain may play a regulatory role, although its exact function is unknown. Mutations of conserved residues within this domain are associated with a variety of human hereditary diseases, including congenital myotonia, idiopathic generalized epilepsy, hypercalciuric nephrolithiasis, and classic Bartter syndrome (CLC chloride channel family members), Wolff-Parkinson-White syndrome (gamma 2 subunit of AMP-activated protein kinase), retinitis pigmentosa (IMP dehydrogenase-1), and homocystinuria (cystathionine beta-synthase).	2.95737e-43

Protein sequences

>NC_008312.1|WP_011614016.1|7277651_7278023_+|hypothetical-protein
MTFKDEFTLLTSNGLNVYEPDDEKIRELYQQFFKVLIPGGILVTSFFTPYPNIDPNSEWDMSQINSKGLLLSKIIMFDILDIKFVAFRSSLITKLQLKTAGFNEIIFFYNAKVYPTVVAGKPK
>NC_008312.1|WP_044137031.1|7276609_7276858_+|(2Fe-2S)-ferredoxin-domain-containing-protein
MENSQVKRLLLVCQSRTCRKQGSAKVLANFQKFDMPNITIKKSGCLGKCGNGPMILVLPEEVWYSHVELQNISVIMEKHLLD
>NC_008312.1|WP_011614014.1|7275613_7276594_+|cysteine-synthase-A
MDIKPGFIGTVGNTPLIRLNSFSEETGCEILGKAEFLNPGGSVKDRAALYIIKDAEEKGLLKPGGTVVEGTAGNTGIGLAHICNAKGYKCLIVIPETQSVEKMDALRTLGAEVKPVPAVPYKNPNNYVKMSGKLASTIENAIWANQFDNLANRIAHYETTGPEIWEQTDGKVDAWVAATGTGGTFAGVSLFLKEKNPQIKTVLADPMGSGLYSYVKTGEISSEGNSITEGIGNSRITKNMENVMIDDAIRVDDKEAVRVVYQLLRKDGLFMGGSVGINVGAAVALAKQMGPGHTIVTVLCDSGTRYQSKLFNREWLATKNLLPDER
>NC_008312.1|WP_011614013.1|7273366_7274410_+|sirohydrochlorin-chelatase
MQYSNQNPKIKTQKILTSTIEKSHLYTEEKLESLPLQRPLLLIGHGTRDSQGKETFLDFVAAYQNLDKSRPVIPCFLELTKPTIQEGVDKCVEQGYTELSALPILLFAARHNKFDITNELDRARQRHPQVKFYYGRHFGITPKIIELWRSRLKELDKTNFNSSETVLLFVGRGSSDPDANGDVYKLARMLWEGSGYLTVETCFIGITHPRLEEGFRRARLYQPKRIMVLPYFLFTGVLVKKIFDITAQQQEQYPDISMTCLPEIGAHPTLLELLREREIETQLGEVKMNCEMCKFRLVTVTNREHSHGHSHHYHDHSHSLNIPEHSHSVVDPYAEPEKYHQRIWQVP
>NC_008312.1|WP_081432519.1|7269189_7269645_+|IS630-family-transposase
MKLINKYSENQLPIRYWCQDETRIGLKTITGKVITACGVKPIGLYQWLFKYLWLYGLVEPKTGDSFFYEFSHLDTPCFERFLELFSQTYPEEIHIIQLDNGRGHLGNDLSIPDHIILLFQPPYCPEVNPIERLWKEVKKFLKNRVFDSLDF
>NC_008312.1|WP_011611074.1|7268677_7269181_+|helix-turn-helix-domain-containing-protein
MSGVVKIEINESVETLKKLLKSASTAQEKERLQTIYWLKTQTVETVKEIAIMLGRNRVTVQKWLGKYRTGGLNLLLEPKKNLGGRPSSIPPNVIEKLEAELQNPEGFQSYGEIQQWLTTCFDIELSYRTVHQLVRFKLKSKLKVPRPNHIKQNKEAQENFKKNSHLN
>NC_008312.1|WP_011611074.1|7266264_7266768_-|helix-turn-helix-domain-containing-protein
MSGVVKIEINESVETLKKLLKSASTAQEKERLQTIYWLKTQTVETVKEIAIMLGRNRVTVQKWLGKYRTGGLNLLLEPKKNLGGRPSSIPPNVIEKLEAELQNPEGFQSYGEIQQWLTTCFDIELSYRTVHQLVRFKLKSKLKVPRPNHIKQNKEAQENFKKNSHLN
>NC_008312.1|WP_081432519.1|7265800_7266256_-|IS630-family-transposase
MKLINKYSENQLPIRYWCQDETRIGLKTITGKVITACGVKPIGLYQWLFKYLWLYGLVEPKTGDSFFYEFSHLDTPCFERFLELFSQTYPEEIHIIQLDNGRGHLGNDLSIPDHIILLFQPPYCPEVNPIERLWKEVKKFLKNRVFDSLDF
>NC_008312.1|WP_011614011.1|7265338_7265716_+|hypothetical-protein
MNKAEILKRKLDNPRPFSSVAWDAYDIPSQACVNPNLKWKDINWKKVEKYVFKLQKLIYRASSRGEIRKMRKYQKLLTKSYYARLLAVRRVTQDNQGKKTAGIDGIKSLPPMQRFNTNFLKSDYT
>NC_008312.1|WP_011614010.1|7263601_7263862_-|hypothetical-protein
MNETTNELVENMPREQRVGQLRNLIETLHIADEVANKGYLITSSELADLMDINASAVTSRGDHWVWRNWVVSRVRREGNQSAIRFC
>NC_008312.1|WP_011614017.1|7278919_7279090_-|hypothetical-protein
MKNNQLRLRMNDKSMNKLRLYLRLQGKTMTQVIEEVIDSLPEVVVEATEQEKMFIK
>NC_008312.1|WP_011614018.1|7279224_7280568_+|glutathione-disulfide-reductase
MAYDYDLFVIGAGSGGLASSKRAASYGAKVAIAENDLVGGTCVIRGCVPKKLMVYGSRFSHFYKDAVGYGWSEVEPSFDWHKLIDAVNTEVLRLNKLHISFLEKAGVEIIEEYAKFIDPHTIEVGDRKVTADKILIAVGGKPEKIDIPGIEYSITSREIFHLKEQPKRMAVWGGGYIGVEFAGILNGVGTEVTQIIRRDSILRGFDTDISSNIQEGMVKHGINFRENTNVEKIEKVPEGLKVHLSGENAEPLIVDTFLCATGRKPNLAGLNLENAGVETLRGAVAVSNNCRTTQANIYAIGDCIDKVNLTPIAIAQGRAFADTEFGNIPRSISLENIPTAVFSEPEGGTVGLTEAAAREKFGDSIKCYRSKFRPMFHSFTGADEKVMVKLVVETNTDRILGVHMVGKDAGEIIQGMAIAVNMGATKADFDRTIGIHPSTAEELVTLN
>NC_008312.1|WP_155994742.1|7280858_7282022_-|DUF4336-domain-containing-protein
MQQQNSNFRDWSWPLWPILPLYPYGQRRTLRKEIVKDTIWTFDQLQGIFYVTVPIRMTVVRMNGGGLFIYAPIAPTRECMRFVNELVEKYGEVRYIILPTISGLEHKVYVGPFARKFPTAEVFVTPNQWSFPLNLPLSWLGLPRNRTYLLPVNSKDTPFAAEFEYATLGPLDIGIKPFAEVVFCHSPSQTLLAVDTILSVPAEPPEILNLDPYPLLFHAKDDVFDVVEDTPTNRCIGWQKICLFGLYFQVDALDVVPAEEMLKNVWKASDRSKRAYFGLLPWRWKSDWQNSFTQLRQDGRLLVAPILQTLILNRDPQQVMEWVEKVATWNFRQVIPCHFDAPIQASGSEFRQGFSFLEKDSGGYLPETDLKFLRNLDEGLKKRGILR
>NC_008312.1|WP_044137032.1|7283270_7283465_-|hypothetical-protein
MINFNGKQIGKLKQYKNHPLLKDLITAAQKINGEPLYFESLGEHPRLSSCGETEPKNIGKKIRV
>NC_008312.1|WP_011614020.1|7284209_7286588_-|CBS-domain-containing-protein
MFAEATIYSSPLQKAIDRHPLTMTPDTLLFDVLQVISQLQNSCLLPNLSISKNQVYPSILLNPINTKCVLVVENKPVQETPKQNIQVSLLGILTTTDIVKLISAGKVNNLESLSKKIYLGEVMKSNIITLKESEDQDLFTALSLFRKYKISHIPVLDRKNQIVGVVTPEKIRQVLQPSNILRLRRVNEIKNDCVTVTISATESLLQVSKLMSEYKVNNVIITQKKKLKTQNKKIEEPIGIVTQDDILQAYFLNMDLAKIPVKTIMDTELNFVKSTNSLWDAQKKMLQEQVQVLLVCSQQGELLGTVNQANLLQVVDPTVMFGLVKKLRADVNQLQAEKLELLRSRNAELEKEVQARTAEIQEQLERDRLLAKIALRIHQSLNLNEIINAAVSEVQQLLTADRVVLFQVKSSKVTKIVAESVVHNCSSWMDNQAIDDYLISNLKVKKNKTYAVADIDQTDLPIEEIRSLKEKQVKAFLIVPICLDGPLWGIMCTQECSGTRQWQASEIDLLKQLGTQLAIAIQQAQLYQQVRILNTDLERQVQERTIELEEKVKELEQLNILKDDFLSTVSHELRTPLSNMKMAIHMLKVFPISEKGQKYLNILDTECKREIELITDLLDLQHLEVSKKSIALDIIDLTTWLPTIVDPFKSRAKERQQIINSKYPQQLPNIRSNNNSLGRILAEILNNACKYTQNGGVIKFSIEINQQKSSNKSLSETLYSIKFIVSNPSEIPESELPKIFNKFYRVPNADPWKQGGTGLGLALVKKLVEQLNGNIIVKSSNGWTTFTVELPS
>NC_008312.1|WP_081432505.1|7288917_7289178_-|hypothetical-protein
MNNKDFKEIQVIKVGKKLTRQRKKRNHKMSYKVKKENQKKAQKRIFVEHVIRLIKILKVARERFRLKESNYEKVILTICGLVRLRD
>NC_008312.1|WP_011614024.1|7290401_7300685_+|DUF4347-domain-containing-protein
MNKQPSLTVWDKSITSFCSYSSKEVSYAEALISNARELVVIDKGVDDYQQLLHSIKPGIYGVVLNPDRDGVQQITQVLRNYRGVETLHILSHGSPGCLYLGNTQLSLETLDKYGEDLQKWFIEVPSANLLIYGCQVAAENTGTEFLSKVQSLTKANIAASANLTGNAILGGDWELEITLGQGEFVRAFTSESLADYASVLDTGNFLVSGLPPFAQIWIDKNNPFPNVSLTETEDKITASYNGTLDITTQINEILTRLNLTPITQQISATNPTLIIEGTAQNPTGYKFSGEFSPTEAIEFLGDTLGVELPNNIQEQLNKVGKVNIQASNQGFGITYLDNVVLDVNNIVGMISDNDFLKDAANTVTETFLGDGDPATEGTQLVLAQPGIEFEKKNNTKKLSFAGDFNGEVFDLSFDVSEIGSKVSGAQKKIPKLSGFKFGLPELDATKMTNAFKTIAGTELPGFAQDLLTTLGGLANLNIELNDNGFGVTYVGGLNISSTINSLLSTLGLGENVLSDSLSVTNPGLRVTKDDTGKKIYAASIGEFSPTEAIEFLGDTLGVELPNNIQEQLNKVGKVNIQASNQGFGITYLDNVVLDVNNIVGMISDNDFLKDAANTVTETFLGDGDPATEGTQLVLAQPGIEFEKKNNTKKLSFAGDFNGEVFDLSFDVSEIGSKVSGAQKKIPKLSGFKFGLPELDATKMTNAFKTIAGTELPGFAQDLLTTLGGLANLNIELNDNGFGVTYVGELNISSTINSLLSTLGLGENVMSQSLTVSHPGLRYATDETGNRNYELSVSEFSPKQLINLLVGLLPSSVSLPSNIRDTINSIGNASLSLSSQGISITYLDNVTFDLNGLIGDSFNSLSFVEDAVNKIAEIVLGDGDKNKPGTQLVLAKPEFELTTESLGIGGLLNDKNFDIDFKDGLEFEYEFGPLNLNSILGDIPGLDGFQLDETSLSFSDGFSLEGNVNFANKNDDVSKFINDYLGVDNVGVALEIGKEDLSLAGILAGDVPLISIGDFKATLKDVALGLEMSATNPIPNFGIDGGMTLEGYDPVQKNEPPLTLIGGLEIDPKSLTGQFNIDADGVWKNPFGLPDSELRELGVQIGATYIPPFIDNVGFVGDLQFGNYDFDAAFLVDITDPQKFAIELTLNEPLGLVDMITGPINSYLINQLDNVPILDEVTGLFNSFSDLVPISVVSIDGPDDDEELDPLIKIVPVETEVLERTLEQGIGFNAAVRVGSKEGTFNFNMNPFSGNPSLEGSLKIPEIDILGVVKISGVPNGKDTDLNLDLKVSPSEAYFRGDGQLEFFGINLAKADFDFSTSGIKVKELSLLNGTLKLSDVEIGKLNNVATAKGELEFLGQKLKAEITQDGQGFKLTTGLVLDFPDWTFLSDTYANLTIRSNGTLEGSQLELDSPLFNFEVSLGEIKNGIGDLVNFAINEVNKLGEQVADFIAQEWNNTVEYVSDTFKSLGNAWNQGISLVSNIFETGVRQVVDWVDKQVQDGWLPWPLDHIVKWVTKTVRQVTNIEYTKNDPNLPQNVSLGDGNQEYDGQGGNDTIDGGNGKDHLMGGVGNDSLKGGNDEDKLEGGAGHDYLHGQRDNDFLYGNDHDDRLYGEDGNDMLDGGSGNDQLYGGNGRDQLKGGSGNDKLYGEDKSDVLEGGMGNDELHGGNDNDVLKGESGKDTLRGGSGSDKLEGGEDHDHLYGESDSDKLEGGQGDDYLNGGDGNDEIDGGKGNDSLVGDQGDDILYGREGNDTLKGDSGNDLIFGGVGNDILYGGTGDDYLDGGEGNDTIYPGSGNDTINGGEGNDLLVLSGAKSDYIITDTSTGKEITNKRDNSKKIVFGIENISYEQIQQGNASNGPLANATVFIDTNSNFQLDKGETQTNTDSNGEYSLPFDLEELDRNGDGEVDAQEAQVVVIGGIDTNTGLPGEIPLISQISATGEYTSTTPLTTLKAVLSSQGIKEKQVERLLNKISGFSLESLSQPLEKFDPYSAIGEGDDSGIEITSGHIKIMNLLLNGTTFLEAAYYTESDGQIQVINALGKVLKTVESFDLSKKQDLQKFYNQLTEELDLSVNNKTIAALSTLVTQSNNLIDKLVEQALSSSVDDVLPSINPIKKQVYSILPDLTQQLVEGKITAGEAQTELKEILNADTFLVEHALNEDRIVKVVASDTVKEGKDKNGQFIITLGEAAPPQGLKILYTISGTATLGQDYQNKDGLFGEINFEPGETEAVIDLKVLDDKISENSESVTINLKYVGNGYALDPMAKTAFLEITDNDKGNNNATKNGIEETGSFGDDEIAGQEKNDKLLGSYGDDMLKGKGGDDKLMGGQGKDTIQGGKGNDEIEGNFGEDVLEGNAGDDVIAGGSEDDLIKGGPGNDFLDGNTGDDQLEGNSGNDQLEGGKGNDILKGNRDNDWLVGEAGEDILNGGPGVDLLRGGEGADVFYFQKPSDKGDLIIDFDPTQGDKIQISRSGFKTNSLEDFKVVVGTLEFKGEEIALIQNNGKTYNNFAELADIVELVDEPKVKTTPEKSKASIEIKPQEAKLNSVANPETTILDDIIKRGQIKVAISGSGNEFDLEFAEVIAAAVFGDASKVKSITSKFSKSFELVADGKADLAAQRITATLGRDGELNVDFAPTYLFDYQTVIVPNDSDITNVSHLNEQTIGVIEGTTALINLQNQLEVEGIKFTPKLFETAEEMIAAYDAGEVDAYSHDRSLILENLDQLSQPENHRLLDVELSKEPISLALPENDSQWADVVRWAGYVPIQAEEFGISSQNIAEFIALNTDDNPTNDSSLGIRRFLGIEGNLGETLGLPNDFAVNIINQVGNYSEIYDRHFSGIEGDRNSLWSDGGFLYSPPFSGSEIDIVIKDNDDRDLLAKIKERGVLKLGLPDNEPGFAVKMSNGEYEGFDVDLGKAIAAAIFGDPEKLEVKTQSFKDSFANTANGVVDISAMGITHNLVRDASLGIDFGPIYLYTGQGVLVRNDSGITVLPALNGRRVGVLEGATSLQNIQDTITELGGDIIPAEFTTNDEMFAAYDDGDIDAVITDMTILNGRVQNLSNPKEHKILDDILSKEPLGLIIDENQSEWSDVVRWVTNALVQAEEYDITSKNIKRLMANNLDDDPNNDSDPVVRQFLGIEGNIGKVLGLPNDFVPNVIKAVGNYGEIYERYFDSNLLPREQNELFSNFGLQYALPLGSEVSPTEQEELGSEDDVYEIQPSTLEDYPDGFQAKGGNDRVTGSMRSDLISGGQGQDTISGNDGDDRIIGGPGVDYLYGKDGNDLLEGRTENDYLFGGPGNDALIGGQGRDKLNGGQGSDFLIGGASKDKFIFATNEEFDVEAIGSDTIDDFNPDDDIILLDKKTFTALESKSGEGFSLETEFASVTKNVATSEALIVYNSNNGKLFYNENGNEPGFGEGGEFALLTDQPAIGADDFLIR
>NC_008312.1|WP_011614025.1|7302433_7303252_-|inositol-monophosphatase
MADLWNQILNFAEKTTFIVGNQLLKDFGNVKADKKADGSLVTKADKWADRVIREAIASSFPTHGILTEESQQIFPSNEWCWIIDPLDGTTNFAKGVPIWGICMGLLYQGIPIFGYVNMPPLSQSYYAFYCQENQTYLTNRPITRAFLNNRQIQPIKDVITGNHLFNICSRSTKILPQLPTKIRMLGVASYNFLLVASGASIGGVEATPRIWDIAASWVIAKAAGAIWIPLRSEDIFPLKIGKDYLSHPFPTLVVGNEELVPYFSAIVEPLIK
>NC_008312.1|WP_011614026.1|7305069_7305693_-|DUF938-domain-containing-protein
MTSFNDARQYAPATERNREFILEVLQRLLPPTGNILEIASGTGEHAIFFSPRLKPRQWFPSDPDPILRESIAAWQKHSPSDNLHLPLNIDARESAWAVEKEDIQIKAIVNINMIHISPWSTCLGLMAGAGRLLPQNGVLYLYGPYKLRGEHTAPSNLAFDQSLQFQNPEWGVRNLEDVVAAAEKEGLKFQEQVQMPANNLSVVFHKG
>NC_008312.1|WP_011614027.1|7307140_7307290_+|hypothetical-protein
MAIEKAFRKYDALRSQFMERFQQATLTRLPVSSEQHDQEYAQPVYPRNI

Crispr_ID: NC_008312_48

• CRISPR_ID: NC_008312_48
• CRISPR_location: 7295115-7295467
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 5 spacers

Consensus repeat of NC_008312_48

Consensus_repeat	Method
GGTGGAAGTGGTAACGACCAACTTTATGG	CRISPRCasFinder

spacers of NC_008312_48

>48.1|7295144|25|NC_008312|CRISPRCasFinder
GGGTGCCGGCCACGACTACCTTCAT
>48.2|7295198|25|NC_008312|CRISPRCasFinder
TAATGATCATGATGACCGCCTATAT
>48.3|7295252|52|NC_008312|CRISPRCasFinder
TGGAAGTGGTAACGACCAACTTTATGGGGGTAACGGGCGAGATCAACTCAAA
>48.4|7295333|25|NC_008312|CRISPRCasFinder
TGAAGATAAAAGCGATGTCCTTGAA
>48.5|7295387|52|NC_008312|CRISPRCasFinder
TGGTAATGATAATGATGTACTCAAAGGTGAGTCTGGCAAAGATACCTTAAGG

CRISPR arrays and Neighbor proteins around NC_008312_48

CRISPR arrays

The CRISPR arrays of NC_008312_48

>merge|NC_008312|48|7295115-7295467|CRISPRCasFinder
GGCGGAAATGATGAAGACAAACTTGAAGGGGGTGCCGGCCACGACTACCTTCATGGCCAAAGGGATAACGACTTCCTCTATGGTAATGATCATGATGACCGCCTATATGGTGAAGATGGAAACGATATGCTTGATGGTGGAAGTGGTAACGACCAACTTTATGGGGGTAACGGGCGAGATCAACTCAAAGGTGGAAGTGGTAACGACAAACTTTATGGTGAAGATAAAAGCGATGTCCTTGAAGGTGGAATGGGAAATGACGAACTTCATGGTGGTAATGATAATGATGTACTCAAAGGTGAGTCTGGCAAAGATACCTTAAGGGGAGGAAGTGGGAGTGACAAGCTTGAAGG

>NC_008312|48|38|7295115-7295467|CRISPRCasFinder
GGCGGAAATGATGAAGACAAACTTGAAGG	GGGTGCCGGCCACGACTACCTTCAT
GGCCAAAGGGATAACGACTTCCTCTATGG	TAATGATCATGATGACCGCCTATAT
GGTGAAGATGGAAACGATATGCTTGATGG	TGGAAGTGGTAACGACCAACTTTATGGGGGTAACGGGCGAGATCAACTCAAA
GGTGGAAGTGGTAACGACAAACTTTATGG	TGAAGATAAAAGCGATGTCCTTGAA
GGTGGAATGGGAAATGACGAACTTCATGG	TGGTAATGATAATGATGTACTCAAAGGTGAGTCTGGCAAAGATACCTTAAGG
GGAGGAAGTGGGAGTGACAAGCTTGAAGG

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_008312.1|WP_011614026.1|7305069_7305693_-|DUF938-domain-containing-protein	unknown	unknown	gnl|CDD|253548
NC_008312.1|WP_011614018.1|7279224_7280568_+|glutathione-disulfide-reductase	unknown	unknown	gnl|CDD|235701
NC_008312.1|WP_011614033.1|7317336_7317684_-|histidine-triad-nucleotide-binding-protein	unknown	unknown	gnl|CDD|238607
NC_008312.1|WP_011614028.1|7307374_7308835_+|FAD-dependent-monooxygenase	unknown	unknown	gnl|CDD|223727
NC_008312.1|WP_155994742.1|7280858_7282022_-|DUF4336-domain-containing-protein	unknown	unknown	gnl|CDD|372974
NC_008312.1|WP_011614020.1|7284209_7286588_-|CBS-domain-containing-protein	unknown	unknown	gnl|CDD|341389
NC_008312.1|WP_011614031.1|7314885_7315557_+|HEAT-repeat-domain-containing-protein	unknown	unknown	gnl|CDD|224331
NC_008312.1|WP_011614016.1|7277651_7278023_+|hypothetical-protein	unknown	unknown	unknown
NC_008312.1|WP_044137031.1|7276609_7276858_+|(2Fe-2S)-ferredoxin-domain-containing-protein	unknown	unknown	gnl|CDD|239278
NC_008312.1|WP_081432505.1|7288917_7289178_-|hypothetical-protein	unknown	unknown	gnl|CDD|372577
NC_008312.1|WP_011614032.1|7315950_7317012_-|photosystem-II-q(b)-protein	unknown	unknown	gnl|CDD|130221
NC_008312.1|WP_011614030.1|7311741_7312917_+|mechanosensitive-ion-channel-family-protein	unknown	unknown	gnl|CDD|366370
NC_008312.1|WP_011614017.1|7278919_7279090_-|hypothetical-protein	unknown	unknown	unknown
NC_008312.1|WP_011614029.1|7309944_7310391_-|cupin-domain-containing-protein	unknown	unknown	gnl|CDD|307270
NC_008312.1|WP_011614027.1|7307140_7307290_+|hypothetical-protein	unknown	unknown	unknown
NC_008312.1|WP_011614014.1|7275613_7276594_+|cysteine-synthase-A	unknown	unknown	gnl|CDD|182672
NC_008312.1|WP_155994743.1|7313949_7314165_+|DUF29-family-protein	unknown	unknown	gnl|CDD|366774
NC_008312.1|WP_011614013.1|7273366_7274410_+|sirohydrochlorin-chelatase	unknown	unknown	gnl|CDD|225049
NC_008312.1|WP_044137032.1|7283270_7283465_-|hypothetical-protein	unknown	unknown	unknown
NC_008312.1|WP_011614025.1|7302433_7303252_-|inositol-monophosphatase	unknown	unknown	gnl|CDD|238821

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_008312.1|WP_011614026.1|7305069_7305693_-|DUF938-domain-containing-protein	gnl|CDD|253548	pfam06080, DUF938, Protein of unknown function (DUF938). This family consists of several hypothetical proteins from both prokaryotes and eukaryotes. The function of this family is unknown.	1.53264e-90
NC_008312.1|WP_011614018.1|7279224_7280568_+|glutathione-disulfide-reductase	gnl|CDD|235701	PRK06116, PRK06116, glutathione reductase; Validated.	0
NC_008312.1|WP_011614028.1|7307374_7308835_+|FAD-dependent-monooxygenase	gnl|CDD|223727	COG0654, UbiH, 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases [Coenzyme metabolism / Energy production and conversion].	1.59014e-39
NC_008312.1|WP_155994742.1|7280858_7282022_-|DUF4336-domain-containing-protein	gnl|CDD|372974	pfam14234, DUF4336, Domain of unknown function (DUF4336).	0
NC_008312.1|WP_011614020.1|7284209_7286588_-|CBS-domain-containing-protein	gnl|CDD|341389	cd04620, CBS_two-component_sensor_histidine_kinase_repeat1, 2 tandem repeats of the CBS domain in the two-component sensor histidine kinase and related-proteins, repeat 1. This cd contains 2 tandem repeats of the CBS domain in the two-component sensor histidine kinase and related-proteins. Two-component regulation is the predominant form of signal recognition and response coupling mechanism used by bacteria to sense and respond to diverse environmental stresses and cues ranging from common environmental stimuli to host signals recognized by pathogens and bacterial cell-cell communication signals. The structures of both sensors and regulators are modular, and numerous variations in domain architecture and composition have evolved to tailor to specific needs in signal perception and signal transduction. The simplest histidine kinase sensors consists of only sensing and kinase domains. The more complex hybrid sensors contain an additional REC domain typical of two-component regulators and in some cases a C-terminal histidine phosphotransferase (HPT) domain. The CBS domain, named after human CBS, is a small domain originally identified in cystathionine beta-synthase and is subsequently found in a wide range of different proteins. CBS domains usually occur in tandem repeats. They associate to form a so-called Bateman domain or a CBS pair based on crystallographic studies in bacteria. The CBS pair was used as a basis for this cd hierarchy since the human CBS proteins can adopt the typical core structure and form an intramolecular CBS pair. The interface between the two CBS domains forms a cleft that is a potential ligand binding site. The CBS pair coexists with a variety of other functional domains and this has been used to help in its classification here. It has been proposed that the CBS domain may play a regulatory role, although its exact function is unknown. Mutations of conserved residues within this domain are associated with a variety of human hereditary diseases, including congenital myotonia, idiopathic generalized epilepsy, hypercalciuric nephrolithiasis, and classic Bartter syndrome (CLC chloride channel family members), Wolff-Parkinson-White syndrome (gamma 2 subunit of AMP-activated protein kinase), retinitis pigmentosa (IMP dehydrogenase-1), and homocystinuria (cystathionine beta-synthase).	2.95737e-43
NC_008312.1|WP_011614031.1|7314885_7315557_+|HEAT-repeat-domain-containing-protein	gnl|CDD|224331	COG1413, COG1413, FOG: HEAT repeat [Energy production and conversion].	1.63699e-35
NC_008312.1|WP_044137031.1|7276609_7276858_+|(2Fe-2S)-ferredoxin-domain-containing-protein	gnl|CDD|239278	cd02980, TRX_Fd_family, Thioredoxin (TRX)-like [2Fe-2S] Ferredoxin (Fd) family; composed of [2Fe-2S] Fds with a TRX fold (TRX-like Fds) and proteins containing domains similar to TRX-like Fd including formate dehydrogenases, NAD-reducing hydrogenases and the subunit E of NADH:ubiquinone oxidoreductase (NuoE). TRX-like Fds are soluble low-potential electron carriers containing a single [2Fe-2S] cluster. The exact role of TRX-like Fd is still unclear. It has been suggested that it may be involved in nitrogen fixation. Its homologous domains in large redox enzymes (such as Nuo and hydrogenases) function as electron carriers.	2.12741e-18
NC_008312.1|WP_081432505.1|7288917_7289178_-|hypothetical-protein	gnl|CDD|372577	pfam13359, DDE_Tnp_4, DDE superfamily endonuclease. This family of proteins are related to pfam00665 and are probably endonucleases of the DDE superfamily. Transposase proteins are necessary for efficient DNA transposition. This domain is a member of the DDE superfamily, which contain three carboxylate residues that are believed to be responsible for coordinating metal ions needed for catalysis. The catalytic activity of this enzyme involves DNA cleavage at a specific site followed by a strand transfer reaction.	1.58528e-06
NC_008312.1|WP_011614032.1|7315950_7317012_-|photosystem-II-q(b)-protein	gnl|CDD|130221	TIGR01151, Photosystem_QB_protein, photosystem II, DI subunit (also called Q(B)). This model describes the Photosystem II, DI subunit (also called Q(B)) in bacterial and its equivalents in chloroplast of algae and higher plants. Photosystem II is many ways functionally equivalent to bacterial reaction center. At the core of Photosystem II are several light harvesting cofactors including plastoquinones, pheophytins, phyloquinones etc. These cofactors are intimately associated with the polypeptides, which principally including subunits DI, DII, Cyt.b, Cyt.f and iron-sulphur protein. Together they participate in the electron transfer reactions that lead to the net production of the reducting equivalents in the form of NADPH, which are used for reduction of CO2 to carbohydrates(C6H1206). Phosystem II operates during oxygenic photosynthesis and principal electron donor is H2O. Although no structural data is presently available, a huge body of literature exits that describes function using a variety of biochemical and biophysical techniques. [Energy metabolism, Electron transport, Energy metabolism, Photosynthesis].	0
NC_008312.1|WP_011614030.1|7311741_7312917_+|mechanosensitive-ion-channel-family-protein	gnl|CDD|366370	pfam00924, MS_channel, Mechanosensitive ion channel. Two members of this protein family of M. jannaschii have been functionally characterized. Both proteins form mechanosensitive (MS) ion channels upon reconstitution into liposomes and functional examination by the patch-clamp technique. Therefore this family are likely to also be MS channel proteins.	8.31532e-14
NC_008312.1|WP_011614029.1|7309944_7310391_-|cupin-domain-containing-protein	gnl|CDD|307270	pfam01050, MannoseP_isomer, Mannose-6-phosphate isomerase. All of the members of this Pfam entry belong to family 2 of the mannose-6-phosphate isomerases. The type II phosphomannose isomerases are bifunctional enzymes. This Pfam entry covers the isomerase domain. The guanosine diphospho-D-mannose pyrophosphorylase domain is in another Pfam entry, see pfam00483.	7.34489e-54
NC_008312.1|WP_011614014.1|7275613_7276594_+|cysteine-synthase-A	gnl|CDD|182672	PRK10717, PRK10717, cysteine synthase A; Provisional.	0
NC_008312.1|WP_155994743.1|7313949_7314165_+|DUF29-family-protein	gnl|CDD|366774	pfam01724, DUF29, Domain of unknown function DUF29. This family consists of various hypothetical proteins from cyanobacteria, none of which are functionally described. The aligned region is approximately 120-140 amino acids long corresponding to almost the entire length of the proteins in the family. Structure 3fcn is a small protein that has a novel all-alpha fold. The N-terminal helical hairpin is likely to function as a dimerization module. This protein is a member of PFam family PF01724. The function of this protein is unknown. One protein sequence contains a fusion of this protein and a DnaB domain, suggesting a possible role in DNA helicase activity (hypothetical). Dali hits have low Z and high rmsd, suggesting probably only topological similarities (not functional relevance) (details derived from TOPSAN). The family has several highly conserved sequence motifs, including YD/ExD, DxxNVxEEIE, and CPY/F/W, as well as conserved tryptophans.	6.93024e-19
NC_008312.1|WP_011614013.1|7273366_7274410_+|sirohydrochlorin-chelatase	gnl|CDD|225049	COG2138, COG2138, Sirohydrochlorin ferrochelatase [Inorganic ion transport and metabolism].	1.56094e-70
NC_008312.1|WP_011614033.1|7317336_7317684_-|histidine-triad-nucleotide-binding-protein	gnl|CDD|238607	cd01276, PKCI_related, Protein Kinase C Interacting protein related (PKCI): PKCI and related proteins belong to the ubiquitous HIT family of hydrolases that act on alpha-phosphates of ribonucleotides. The members of this subgroup have a conserved HxHxHxx motif (x is a hydrophobic residue) that is a signature for this family. No enzymatic activity has been reported however, for PKCI and its related members.	4.99136e-58
NC_008312.1|WP_011614025.1|7302433_7303252_-|inositol-monophosphatase	gnl|CDD|238821	cd01643, Bacterial_IMPase_like_2, Bacterial family of Mg++ dependent phosphatases, related to inositol monophosphatases. These enzymes may dephosphorylate inositol monophosphate or similar substrates.	1.09028e-113

Protein sequences

>NC_008312.1|WP_081432505.1|7288917_7289178_-|hypothetical-protein
MNNKDFKEIQVIKVGKKLTRQRKKRNHKMSYKVKKENQKKAQKRIFVEHVIRLIKILKVARERFRLKESNYEKVILTICGLVRLRD
>NC_008312.1|WP_011614020.1|7284209_7286588_-|CBS-domain-containing-protein
MFAEATIYSSPLQKAIDRHPLTMTPDTLLFDVLQVISQLQNSCLLPNLSISKNQVYPSILLNPINTKCVLVVENKPVQETPKQNIQVSLLGILTTTDIVKLISAGKVNNLESLSKKIYLGEVMKSNIITLKESEDQDLFTALSLFRKYKISHIPVLDRKNQIVGVVTPEKIRQVLQPSNILRLRRVNEIKNDCVTVTISATESLLQVSKLMSEYKVNNVIITQKKKLKTQNKKIEEPIGIVTQDDILQAYFLNMDLAKIPVKTIMDTELNFVKSTNSLWDAQKKMLQEQVQVLLVCSQQGELLGTVNQANLLQVVDPTVMFGLVKKLRADVNQLQAEKLELLRSRNAELEKEVQARTAEIQEQLERDRLLAKIALRIHQSLNLNEIINAAVSEVQQLLTADRVVLFQVKSSKVTKIVAESVVHNCSSWMDNQAIDDYLISNLKVKKNKTYAVADIDQTDLPIEEIRSLKEKQVKAFLIVPICLDGPLWGIMCTQECSGTRQWQASEIDLLKQLGTQLAIAIQQAQLYQQVRILNTDLERQVQERTIELEEKVKELEQLNILKDDFLSTVSHELRTPLSNMKMAIHMLKVFPISEKGQKYLNILDTECKREIELITDLLDLQHLEVSKKSIALDIIDLTTWLPTIVDPFKSRAKERQQIINSKYPQQLPNIRSNNNSLGRILAEILNNACKYTQNGGVIKFSIEINQQKSSNKSLSETLYSIKFIVSNPSEIPESELPKIFNKFYRVPNADPWKQGGTGLGLALVKKLVEQLNGNIIVKSSNGWTTFTVELPS
>NC_008312.1|WP_044137032.1|7283270_7283465_-|hypothetical-protein
MINFNGKQIGKLKQYKNHPLLKDLITAAQKINGEPLYFESLGEHPRLSSCGETEPKNIGKKIRV
>NC_008312.1|WP_155994742.1|7280858_7282022_-|DUF4336-domain-containing-protein
MQQQNSNFRDWSWPLWPILPLYPYGQRRTLRKEIVKDTIWTFDQLQGIFYVTVPIRMTVVRMNGGGLFIYAPIAPTRECMRFVNELVEKYGEVRYIILPTISGLEHKVYVGPFARKFPTAEVFVTPNQWSFPLNLPLSWLGLPRNRTYLLPVNSKDTPFAAEFEYATLGPLDIGIKPFAEVVFCHSPSQTLLAVDTILSVPAEPPEILNLDPYPLLFHAKDDVFDVVEDTPTNRCIGWQKICLFGLYFQVDALDVVPAEEMLKNVWKASDRSKRAYFGLLPWRWKSDWQNSFTQLRQDGRLLVAPILQTLILNRDPQQVMEWVEKVATWNFRQVIPCHFDAPIQASGSEFRQGFSFLEKDSGGYLPETDLKFLRNLDEGLKKRGILR
>NC_008312.1|WP_011614018.1|7279224_7280568_+|glutathione-disulfide-reductase
MAYDYDLFVIGAGSGGLASSKRAASYGAKVAIAENDLVGGTCVIRGCVPKKLMVYGSRFSHFYKDAVGYGWSEVEPSFDWHKLIDAVNTEVLRLNKLHISFLEKAGVEIIEEYAKFIDPHTIEVGDRKVTADKILIAVGGKPEKIDIPGIEYSITSREIFHLKEQPKRMAVWGGGYIGVEFAGILNGVGTEVTQIIRRDSILRGFDTDISSNIQEGMVKHGINFRENTNVEKIEKVPEGLKVHLSGENAEPLIVDTFLCATGRKPNLAGLNLENAGVETLRGAVAVSNNCRTTQANIYAIGDCIDKVNLTPIAIAQGRAFADTEFGNIPRSISLENIPTAVFSEPEGGTVGLTEAAAREKFGDSIKCYRSKFRPMFHSFTGADEKVMVKLVVETNTDRILGVHMVGKDAGEIIQGMAIAVNMGATKADFDRTIGIHPSTAEELVTLN
>NC_008312.1|WP_011614017.1|7278919_7279090_-|hypothetical-protein
MKNNQLRLRMNDKSMNKLRLYLRLQGKTMTQVIEEVIDSLPEVVVEATEQEKMFIK
>NC_008312.1|WP_011614016.1|7277651_7278023_+|hypothetical-protein
MTFKDEFTLLTSNGLNVYEPDDEKIRELYQQFFKVLIPGGILVTSFFTPYPNIDPNSEWDMSQINSKGLLLSKIIMFDILDIKFVAFRSSLITKLQLKTAGFNEIIFFYNAKVYPTVVAGKPK
>NC_008312.1|WP_044137031.1|7276609_7276858_+|(2Fe-2S)-ferredoxin-domain-containing-protein
MENSQVKRLLLVCQSRTCRKQGSAKVLANFQKFDMPNITIKKSGCLGKCGNGPMILVLPEEVWYSHVELQNISVIMEKHLLD
>NC_008312.1|WP_011614014.1|7275613_7276594_+|cysteine-synthase-A
MDIKPGFIGTVGNTPLIRLNSFSEETGCEILGKAEFLNPGGSVKDRAALYIIKDAEEKGLLKPGGTVVEGTAGNTGIGLAHICNAKGYKCLIVIPETQSVEKMDALRTLGAEVKPVPAVPYKNPNNYVKMSGKLASTIENAIWANQFDNLANRIAHYETTGPEIWEQTDGKVDAWVAATGTGGTFAGVSLFLKEKNPQIKTVLADPMGSGLYSYVKTGEISSEGNSITEGIGNSRITKNMENVMIDDAIRVDDKEAVRVVYQLLRKDGLFMGGSVGINVGAAVALAKQMGPGHTIVTVLCDSGTRYQSKLFNREWLATKNLLPDER
>NC_008312.1|WP_011614013.1|7273366_7274410_+|sirohydrochlorin-chelatase
MQYSNQNPKIKTQKILTSTIEKSHLYTEEKLESLPLQRPLLLIGHGTRDSQGKETFLDFVAAYQNLDKSRPVIPCFLELTKPTIQEGVDKCVEQGYTELSALPILLFAARHNKFDITNELDRARQRHPQVKFYYGRHFGITPKIIELWRSRLKELDKTNFNSSETVLLFVGRGSSDPDANGDVYKLARMLWEGSGYLTVETCFIGITHPRLEEGFRRARLYQPKRIMVLPYFLFTGVLVKKIFDITAQQQEQYPDISMTCLPEIGAHPTLLELLREREIETQLGEVKMNCEMCKFRLVTVTNREHSHGHSHHYHDHSHSLNIPEHSHSVVDPYAEPEKYHQRIWQVP
>NC_008312.1|WP_011614025.1|7302433_7303252_-|inositol-monophosphatase
MADLWNQILNFAEKTTFIVGNQLLKDFGNVKADKKADGSLVTKADKWADRVIREAIASSFPTHGILTEESQQIFPSNEWCWIIDPLDGTTNFAKGVPIWGICMGLLYQGIPIFGYVNMPPLSQSYYAFYCQENQTYLTNRPITRAFLNNRQIQPIKDVITGNHLFNICSRSTKILPQLPTKIRMLGVASYNFLLVASGASIGGVEATPRIWDIAASWVIAKAAGAIWIPLRSEDIFPLKIGKDYLSHPFPTLVVGNEELVPYFSAIVEPLIK
>NC_008312.1|WP_011614026.1|7305069_7305693_-|DUF938-domain-containing-protein
MTSFNDARQYAPATERNREFILEVLQRLLPPTGNILEIASGTGEHAIFFSPRLKPRQWFPSDPDPILRESIAAWQKHSPSDNLHLPLNIDARESAWAVEKEDIQIKAIVNINMIHISPWSTCLGLMAGAGRLLPQNGVLYLYGPYKLRGEHTAPSNLAFDQSLQFQNPEWGVRNLEDVVAAAEKEGLKFQEQVQMPANNLSVVFHKG
>NC_008312.1|WP_011614027.1|7307140_7307290_+|hypothetical-protein
MAIEKAFRKYDALRSQFMERFQQATLTRLPVSSEQHDQEYAQPVYPRNI
>NC_008312.1|WP_011614028.1|7307374_7308835_+|FAD-dependent-monooxygenase
MTEENSIPKIDYDVVIVGAGPVGLATALGLYQRGIENIIVLDQTRAFRQVGQTISIFPNGLKALKYIDTEAYKNIKATIDQPHNSLQVSQKTEVEKKQPSPYWNLINVNGQKIRSFLVGYNEYFEKYGEGKVSISWYNLQTQLRKLLPVECVKANHCCINVVTEPEFQCVRADFVSNQEVEIHPYVYWDDQQQKNKSSSLNSSQFSESKITSIRAKLLIGVDGINSRVRQVIYQNTLYSEYSKPKYCGVGAICTGNFFDSRAVQIAETLSEKIKEKFFHGSPRVITIKNHQILESDLPRIMLFSPQPCQFGYVFHGAFPLDLLLEKSGEELINIAIKELKKADFPEIIQQLVALSDPDKMIQRLYYTHHATVSAPEQPKWNIGRVVLAGDAAHGMPPFLGQGVNQGLEDAAAIATLVNQINKQNQWDDMAAIQLAFSKYEALRRPFMTYIQQETLIGRPFSSYEKLQKYNQVVLSRNIEEVMQTLL
>NC_008312.1|WP_011614029.1|7309944_7310391_-|cupin-domain-containing-protein
MSEIENHQQPSTPFLDSEANNEQKYPTRTPPWGTVTILEEGLRYKISRIEVKPKHYISTQMHYHRSEHWIVVSGTAKVTFNDQEKLLFQKQSTYVPANTAHRVENPGIIPLIMIEIQNGEYLGEDDIIRFPDEDNQLFSFKKAITNKE
>NC_008312.1|WP_011614030.1|7311741_7312917_+|mechanosensitive-ion-channel-family-protein
MLNQVFYPEKQPVNSSLIEEKKRMEFLETLWRNIETTNFFGIPAFKPLLAFGILLLTIIFQGIISKTIVKYIKYLTVKAGYNLDDNLLELIKKPLTFLIFAVALRIIQTILARGALDPNLSSLIFLTLVAFLLYNAAPLLAKLLEFLTMQTETELDDLLVPYVPKLVRIGTVVVVIIKASEVFLGASAGALIGLLGGAGVALGLLFKDIIYDWCCTIIIFTDGLYKPGDWAVVSGEFVQVVEIGLRTTKLYSWEWGSIKKMPNSRMVSGIVDNWSQDQSEIKEWGFKGAINIDCITSDQVEIMLKGMNQLFESIDGFYPGKYKCKFQGIQGNARVLSYMAKIDPNYYTSAINKFLLGLMKLMEKEGIHTQNIHFITDQDTYESNMKMASKN
>NC_008312.1|WP_155994743.1|7313949_7314165_+|DUF29-family-protein
MFYHHDFIAWCEDTAPKLKSRELDDLDSIDLIEKIESLGKSERRELKNRLIAFLAHILKLMYINALKKSNI
>NC_008312.1|WP_011614031.1|7314885_7315557_+|HEAT-repeat-domain-containing-protein
MQNMNLEQISVQLDSENSRDRLLALAHLREVSATEAVPLIKKVLYDSNLPVRSMAVFALGLKQTEECYPILVELLEKDPDYGVRADAAGALGYLGDVRAFKPLAQAFYQDTSWLVRFSATVALGNLRDQRAHDLLIEALDSQELVIQQAAIAALGEIGDLKAVDHILKFALSEDWLIRQNLAKALGNISIPKSISALKYLEKDTHPQVSQAASISLQHLLKLS
>NC_008312.1|WP_011614032.1|7315950_7317012_-|photosystem-II-q(b)-protein
MTTTLQQRENANVWERFCSWVTSTDNRIYVGWFGVLMIPTLLTATICYIIAFVAAPPVDIDGIREPVAGSLMFGNNIISGAVVPSSNAIGLHFYPIWEAASLDEWLYNGGPYQLVIFHFLIGIFTYMGREWELSYRLGMRPWICVAYSAPVAAATAVFLIYPIGQGSFSDGMPLGISGTFNFMIVFQAEHNILMHPFHMLGVAGVFGGSLFSAMHGSLVTSSLVRETTETESQNYGYKFGQEEETYNIVAAHGYFGRLIFQYASFNNSRSLHFFLGAWPVVGIWFTALGVSTMAFNLNGFNFNQSIIDSSGRVINTWADIINRANLGMEVMHERNAHNFPLDLAAVEAPSIKG
>NC_008312.1|WP_011614033.1|7317336_7317684_-|histidine-triad-nucleotide-binding-protein
MSEQDTIFSKIIRREIPADIIYEDETTLAFKDINPQAPIHILVIPKKPIPNLANATSEDHILMGNLLLTAKQVAQEQGLQNGYRVVINNGIDAGQTVFHLHLHILGGRPMQWPPG

Crispr_ID: NC_008312_49

• CRISPR_ID: NC_008312_49
• CRISPR_location: 7422123-7422217
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NC_008312_49

Consensus_repeat	Method
TCTCCAAAATAAAAATTAAGGTAAAATT	CRISPRCasFinder

spacers of NC_008312_49

>49.1|7422151|39|NC_008312|CRISPRCasFinder
CTAGTGATAAATTATATATACGCTGTCCCCAAATAGACC

CRISPR arrays and Neighbor proteins around NC_008312_49

CRISPR arrays

The CRISPR arrays of NC_008312_49

>merge|NC_008312|49|7422123-7422217|CRISPRCasFinder
TCTCCAAAATAAAAATTAAGGTAAAATTCTAGTGATAAATTATATATACGCTGTCCCCAAATAGACCTCTCCAAAATAGAAATTAAGGTAAAATT

>NC_008312|49|39|7422123-7422217|CRISPRCasFinder
TCTCCAAAATAAAAATTAAGGTAAAATT	CTAGTGATAAATTATATATACGCTGTCCCCAAATAGACC
TCTCCAAAATAGAAATTAAGGTAAAATT

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_008312.1|WP_081432509.1|7422952_7423129_+|hypothetical-protein	unknown	unknown	gnl|CDD|372577
NC_008312.1|WP_155994602.1|7432119_7432284_+|hypothetical-protein	unknown	unknown	unknown
NC_008312.1|WP_011614088.1|7428606_7429086_+|transposase	unknown	unknown	unknown
NC_008312.1|WP_011614086.1|7425906_7426380_-|transposase	unknown	unknown	gnl|CDD|372577
NC_008312.1|WP_155994749.1|7397681_7397837_+|NgoFVII-family-restriction-endonuclease	unknown	unknown	gnl|CDD|370563
NC_008312.1|WP_011614079.1|7411294_7411717_+|anti-sigma-regulatory-factor	unknown	unknown	gnl|CDD|225083
NC_008312.1|WP_011614087.1|7426400_7426775_-|DDE-transposase-family-protein	unknown	unknown	gnl|CDD|372649
NC_008312.1|WP_044137038.1|7416578_7416758_+|hypothetical-protein	unknown	unknown	gnl|CDD|372577
NC_008312.1|WP_011614075.1|7402562_7403309_-|isoprenylcysteine-carboxylmethyltransferase-family-protein	unknown	unknown	gnl|CDD|224931
NC_008312.1|WP_155994601.1|7422356_7422590_+|DDE-transposase-family-protein	unknown	unknown	gnl|CDD|372649
NC_008312.1|WP_011614074.1|7401162_7402356_-|class-I-SAM-dependent-methyltransferase	unknown	unknown	gnl|CDD|224481
NC_008312.1|WP_011614076.1|7406253_7407438_-|NAD(P)H-quinone-oxidoreductase-subunit-H	unknown	unknown	gnl|CDD|180969
NC_008312.1|WP_011614080.1|7413756_7414683_+|tRNA-epoxyqueuosine(34)-reductase-QueG	unknown	unknown	gnl|CDD|272993
NC_008312.1|WP_011614083.1|7420787_7421825_+|UDP-3-O-(3-hydroxymyristoyl)glucosamine-N-acyltransferase	unknown	unknown	gnl|CDD|234858
NC_008312.1|WP_011614085.1|7422645_7422951_+|transposase	unknown	unknown	gnl|CDD|372577
NC_008312.1|WP_081432510.1|7423846_7423948_+|hypothetical-protein	unknown	unknown	gnl|CDD|224576
NC_008312.1|WP_011614078.1|7409628_7411290_+|SpoIIE-family-protein-phosphatase	unknown	unknown	gnl|CDD|381113
NC_008312.1|WP_011609968.1|7423516_7423696_+|hypothetical-protein	unknown	unknown	gnl|CDD|226202
NC_008312.1|WP_063823355.1|7432429_7432852_+|transposase	unknown	unknown	gnl|CDD|376980
NC_008312.1|WP_011614077.1|7408134_7408986_+|16S-rRNA-(cytosine(1402)-N(4))-methyltransferase-RsmH	unknown	unknown	gnl|CDD|234597

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_008312.1|WP_081432509.1|7422952_7423129_+|hypothetical-protein	gnl|CDD|372577	pfam13359, DDE_Tnp_4, DDE superfamily endonuclease. This family of proteins are related to pfam00665 and are probably endonucleases of the DDE superfamily. Transposase proteins are necessary for efficient DNA transposition. This domain is a member of the DDE superfamily, which contain three carboxylate residues that are believed to be responsible for coordinating metal ions needed for catalysis. The catalytic activity of this enzyme involves DNA cleavage at a specific site followed by a strand transfer reaction.	6.15941e-06
NC_008312.1|WP_011614086.1|7425906_7426380_-|transposase	gnl|CDD|372577	pfam13359, DDE_Tnp_4, DDE superfamily endonuclease. This family of proteins are related to pfam00665 and are probably endonucleases of the DDE superfamily. Transposase proteins are necessary for efficient DNA transposition. This domain is a member of the DDE superfamily, which contain three carboxylate residues that are believed to be responsible for coordinating metal ions needed for catalysis. The catalytic activity of this enzyme involves DNA cleavage at a specific site followed by a strand transfer reaction.	2.95759e-40
NC_008312.1|WP_155994749.1|7397681_7397837_+|NgoFVII-family-restriction-endonuclease	gnl|CDD|370563	pfam09565, RE_NgoFVII, NgoFVII restriction endonuclease. This family includes the NgoFVII (recognizes GCSGC but cleavage site unknown) restriction endonuclease.	1.06673e-08
NC_008312.1|WP_011614079.1|7411294_7411717_+|anti-sigma-regulatory-factor	gnl|CDD|225083	COG2172, RsbW, Anti-sigma regulatory factor (Ser/Thr protein kinase) [Signal transduction mechanisms].	8.23141e-26
NC_008312.1|WP_011614087.1|7426400_7426775_-|DDE-transposase-family-protein	gnl|CDD|372649	pfam13613, HTH_Tnp_4, Helix-turn-helix of DDE superfamily endonuclease. This domain is the probable DNA-binding region of transposase enzymes, necessary for efficient DNA transposition. Most of the members derive from the IS superfamily IS5 and rather fewer from IS4.	1.816e-17
NC_008312.1|WP_044137038.1|7416578_7416758_+|hypothetical-protein	gnl|CDD|372577	pfam13359, DDE_Tnp_4, DDE superfamily endonuclease. This family of proteins are related to pfam00665 and are probably endonucleases of the DDE superfamily. Transposase proteins are necessary for efficient DNA transposition. This domain is a member of the DDE superfamily, which contain three carboxylate residues that are believed to be responsible for coordinating metal ions needed for catalysis. The catalytic activity of this enzyme involves DNA cleavage at a specific site followed by a strand transfer reaction.	5.69409e-05
NC_008312.1|WP_011614075.1|7402562_7403309_-|isoprenylcysteine-carboxylmethyltransferase-family-protein	gnl|CDD|224931	COG2020, STE14, Putative protein-S-isoprenylcysteine methyltransferase [Posttranslational modification, protein turnover, chaperones].	4.77158e-09
NC_008312.1|WP_155994601.1|7422356_7422590_+|DDE-transposase-family-protein	gnl|CDD|372649	pfam13613, HTH_Tnp_4, Helix-turn-helix of DDE superfamily endonuclease. This domain is the probable DNA-binding region of transposase enzymes, necessary for efficient DNA transposition. Most of the members derive from the IS superfamily IS5 and rather fewer from IS4.	8.42381e-13
NC_008312.1|WP_011614074.1|7401162_7402356_-|class-I-SAM-dependent-methyltransferase	gnl|CDD|224481	COG1565, COG1565, Uncharacterized conserved protein [Function unknown].	1.04783e-115
NC_008312.1|WP_011614076.1|7406253_7407438_-|NAD(P)H-quinone-oxidoreductase-subunit-H	gnl|CDD|180969	PRK07415, PRK07415, NAD(P)H-quinone oxidoreductase subunit H; Validated.	0
NC_008312.1|WP_011614080.1|7413756_7414683_+|tRNA-epoxyqueuosine(34)-reductase-QueG	gnl|CDD|272993	TIGR00276, iron-sulfur_cluster-binding_protein, epoxyqueuosine reductase. This model was rebuilt to exclude archaeal homologs, now that there is new information that bacterial members are epoxyqueuosine reductase, QueG, involved in queuosine biosynthesis for tRNA maturation. [Protein synthesis, tRNA and rRNA base modification].	5.65847e-124
NC_008312.1|WP_011614083.1|7420787_7421825_+|UDP-3-O-(3-hydroxymyristoyl)glucosamine-N-acyltransferase	gnl|CDD|234858	PRK00892, lpxD, UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase; Provisional.	8.11201e-154
NC_008312.1|WP_011614085.1|7422645_7422951_+|transposase	gnl|CDD|372577	pfam13359, DDE_Tnp_4, DDE superfamily endonuclease. This family of proteins are related to pfam00665 and are probably endonucleases of the DDE superfamily. Transposase proteins are necessary for efficient DNA transposition. This domain is a member of the DDE superfamily, which contain three carboxylate residues that are believed to be responsible for coordinating metal ions needed for catalysis. The catalytic activity of this enzyme involves DNA cleavage at a specific site followed by a strand transfer reaction.	8.99772e-18
NC_008312.1|WP_081432510.1|7423846_7423948_+|hypothetical-protein	gnl|CDD|224576	COG1662, InsB, Transposase and inactivated derivatives, IS1 family [DNA replication, recombination, and repair].	0.000604386
NC_008312.1|WP_011614078.1|7409628_7411290_+|SpoIIE-family-protein-phosphatase	gnl|CDD|381113	cd17569, REC_HupR-like, phosphoacceptor receiver (REC) domain of hydrogen uptake protein regulator (HupR) and similar domains. This family is composed of mostly uncharacterized response regulators with similarity to the REC domains of response regulator components of two-component systems that regulates hydrogenase activity, including HupR and HoxA. HupR is part of the HupT/HupR system that controls the synthesis of the membrane-bound [NiFe]hydrogenase, HupSL, of the photosynthetic bacterium Rhodobacter capsulatus. It contains an N-terminal REC domain, a central sigma-54 interaction domain that lacks ATPase activity, and a C-terminal DNA-binding domain. Members of this family contain a REC domain and various output domains including the cyclase homology domain (CHD) and the c-di-GMP phosphodiesterase domains, HD-GYP and EAL. REC domains function as phosphorylation-mediated switches within response regulators, but some also transfer phosphoryl groups in multistep phosphorelays.	1.57497e-53
NC_008312.1|WP_011609968.1|7423516_7423696_+|hypothetical-protein	gnl|CDD|226202	COG3677, COG3677, Transposase and inactivated derivatives [DNA replication, recombination, and repair].	2.66203e-07
NC_008312.1|WP_063823355.1|7432429_7432852_+|transposase	gnl|CDD|376980	pfam03050, DDE_Tnp_IS66, Transposase IS66 family. Transposase proteins are necessary for efficient DNA transposition. This family includes IS66 from Agrobacterium tumefaciens.	7.37574e-12
NC_008312.1|WP_011614077.1|7408134_7408986_+|16S-rRNA-(cytosine(1402)-N(4))-methyltransferase-RsmH	gnl|CDD|234597	PRK00050, PRK00050, 16S rRNA (cytosine(1402)-N(4))-methyltransferase RsmH.	3.30492e-154

Protein sequences

>NC_008312.1|WP_011614083.1|7420787_7421825_+|UDP-3-O-(3-hydroxymyristoyl)glucosamine-N-acyltransferase
MKFSKLASKLGSETITCSLEKINHLDPDIQGVAAIDEAKPGTLSYIEGAKFANYLKTTNASALILPMDETLQKLAGERGIGWLSSKEPRLLFAQAIALFYRPFQPTPEIHATSIVHPTAKVGKNVYLGAHVVVEAGVKIGDNVCIYPNVVIYPNVEIGENTILNANCSIHERSQIGKGCVIHSGAVIGGEGFGFVPTPEGWFKMEQSGKVILEDGVEVGGNTTIDRPAVGETRIGKNTKLDNLVQIGHGCKIGKNCALAAQVGLAGGVKLGDNVILAGQVGVANQAKIGDRAIATAQAGVHNDVAAGEIVSSSPAVPNKIYLKASAIYKRLPEIYQFVKQMKRKL
>NC_008312.1|WP_044137038.1|7416578_7416758_+|hypothetical-protein
MPPKIKEENQEKAKKRIFLEHVIRLIKIFRLPRKRFRLKNNNYQKVILKICSLVRLIIG
>NC_008312.1|WP_011614080.1|7413756_7414683_+|tRNA-epoxyqueuosine(34)-reductase-QueG
MKLYISSSQIKQKALEVGFHKVGITSANKLSSEINRLQSWLNKGYQADLEWMANPKRQDLKKVMPEVKSVICVALNYYTPHKHSESSEIGKISRYGWGRDYHKVMHKKLKSLVNWLQEQDQEILTRYYVDTGPIMEKPLAEQAGVGWIAKNGNLITREYGSWVFLGEVLTNLELTNDRPHTEHCGSCTRCLEACPTNAIVESFVIDANLCIAYHTIENRNPKLPVHIKSNLKGWVAGCDICQDVCPWNQRFAQETNIDEFQPYPNNLVPKLTKLAEISQEDWNKQFPASALRRIKPEMLQRNARANLE
>NC_008312.1|WP_011614079.1|7411294_7411717_+|anti-sigma-regulatory-factor
MKTELQVPSDINFLTIVENWLLSSLEIELGKHIDWPRQSNRLRLVLAEAYSNVIRHAHKDKPHLPVLIRLEIKNNDIALEIWDYGQGYHTEDYNPPTPDAKQESGYGWLIMNRLMDNVEYRLQIDGRNCLKLEASIPEDI
>NC_008312.1|WP_011614078.1|7409628_7411290_+|SpoIIE-family-protein-phosphatase
MSLGDRKLKLLVVDDEPDNLDLLYRTFRRDFKVYKADSAFTAMDVLKAEGEMALIISDQRMPEMNGTEFLGRTFEIFPDTVRILLTGYTDVEDLVEAINSGKVFKYITKPWTPEELKLVVQQASETYKVLKQRTKTLTLALRRESILNEVMSVIRESLDYSDMLSTIVKTVGQTFTATEGILWPVAGDRLISKPVSYQSSENTEKNFPITEELLLQVVKSRQTYFEEGSNKNSCKLIVPLIYQQDLLAVLALNQQNSSNFWSDEDIKFIESVLEQGALALSQAKLYQRTRELAEQMRNELEVARQIQSNLLRQSWPDFDKFRIQACCYPAREVGGDFFEVYTHPQGEIWLALGDVSGKGVPAALFMASAISLMRRELSQENSPEPYEVMHNLNSSLSDDLISSNCFITMVLARYTPENGSLAYANAGHIYPLVWSKNPLVNTGNKGSEQVPNFLKDRGIPLGILPIWRGKAGTIELDSGDVFLLTSDGITEATVVQKATDSGEVSRVMLQQEGLWKLLKEHKSQLDLNSLLAYIRTDNQVQEDDQTILSLEVL
>NC_008312.1|WP_011614077.1|7408134_7408986_+|16S-rRNA-(cytosine(1402)-N(4))-methyltransferase-RsmH
MNHIPVLSSELISGLVIRPRGLYLDATLGFGGHTKLILAAAPEVKVVAIDQDKQALDSSQTLLASYNSNIQFCHSNFADYDPQNLKFDGILADLGINSVQLDTPERGFSFRHQGKLDMRMNQQQTITAAKIINHWEEVKLANIFYTYGEERLSRRIARKIIESRPLETTTELAEVVANCVPYKYRYGRIHPATRVFQALRIEVNQELSRLETFLKNAPHWLKIGGRIGIISFHSLEDRLVKHSLRNASILKVLTKKPIQPQDNEVAINPRARSAKLRLAEKLS
>NC_008312.1|WP_011614076.1|7406253_7407438_-|NAD(P)H-quinone-oxidoreductase-subunit-H
MSQIQTRTEPMVINMGPHHPSMHGVLRLIVTLDGEDVIDCEPVIGYLHRGMEKIAENRTNTMFVPYVSRWDYAAGMFNEAVTVNAPEQLADIAVPKRASYIRVIMLELNRIANHLLWLGPFLADVGAQTPFFYIFREREMIYDLWEAATGYRMVNNNYFRIGGVAADLPYGWVDKCEDFCDYFLPKVDEYERLITNNPIFRRRIMGLGVISREEAINWGLSGPMLRASGVKWDLRKVDHYECYDDFDWEVHWEKDGDCLARYLVRIREMRESVNIIRQAIKGLPGGPYENLEAKRMAEGPKSEWNDFDYQFLGKKIPPTFKIPKGEHYVRIESGKGEIGIYIIGDNNIFPWRFKIRAADFVNLQIFPHILQGAKVADLVAILGSIDIIMGSVDR
>NC_008312.1|WP_011614075.1|7402562_7403309_-|isoprenylcysteine-carboxylmethyltransferase-family-protein
MSRTLVFIYGIVCYLISLMTFLYTIGFVGNLIVPKTLDLNLDGSLIKGLLIDILLIFLFGVQHSIMARQSFKKWWTKIIPEVIERSTYVLMASLVLLLLCWQWSSFGGIIWNIQNPIIFNVIYGIFAVGWLIVFLSTFMINHFDLFGLRQVYLYWRGQEYEDLEFRNPGFYKYIRHPIMLGFLIAFWATPLMTSSHLVFAIGITIYVLIGIKLEEVDMISIYGNLYQEYRQQVSMLIPVPKIKFIKHK
>NC_008312.1|WP_011614074.1|7401162_7402356_-|class-I-SAM-dependent-methyltransferase
MNQPQLTISNNNENLCTIIYKSISESQNKRITFAEYMDLVLYHPQYGYYATHPVNIGKQGDFLTSPHWGSDFGELLAEQFLQMWHILQRPNNFTIVEMGAGQGILAEQILGYLKQKHLDFFQTVEYLIVEKSEVLKVQQKQILQSYQVRWSDWDKISHSSITGCFFSNELVDAFPVHKFRIEEREIKEIYVSSNSQGKFVEITDKISTPEIAEYFNLVDIDLLSFVDVEGYQSEVNLQALDWIKIVSNKLLKGYLLTIDYGYQAVRYYNPVRKEGTLQCYYQHHRNNDPYWNVGRQDITAHVDFTALEKQGNLLDLETLGFTKQGLFLMALGLGDRLNELSNNQGFSVEEVFRRREALHSLIDPIGLGNFGVLVQSKSLSEEEKKQTLKGLSMPPMG
>NC_008312.1|WP_155994749.1|7397681_7397837_+|NgoFVII-family-restriction-endonuclease
MIVDIASTKNPIYPQRDFVAYTDDGLVFPCRTQGDYYKNLRSRDDLKILGH
>NC_008312.1|WP_155994601.1|7422356_7422590_+|DDE-transposase-family-protein
MKTKKDRRSNKEEKRLIKAGGVRKKSLGKAEEIILTLYYLHHVPTFQLLGAIFGVSESTANNIFQALERYFEGIITI
>NC_008312.1|WP_011614085.1|7422645_7422951_+|transposase
MTEIELIVDSTEQDIFRPKNDEKQKKYYSEKQKSHRLKNQIIITDNGKEIVDVIVGERGPESDIILFKKQQKKFDKEQRFQGDKGYQGGERIDTPKKKNKP
>NC_008312.1|WP_081432509.1|7422952_7423129_+|hypothetical-protein
MSYKVNKENQKKAQKRIFVEHVIRLIKILKVARERFRLKESNYEKVILTICGLVRLRD
>NC_008312.1|WP_011609968.1|7423516_7423696_+|hypothetical-protein
MSIHKLICPSCGSNHIVKNGTIHNKKQKYQCQNCQRQFVENSQRDYISNETKELIDKLK
>NC_008312.1|WP_081432510.1|7423846_7423948_+|hypothetical-protein
MWSFVGNKNNKQWLWLAIDIETKEIVGFYLAGL
>NC_008312.1|WP_011614086.1|7425906_7426380_-|transposase
MELELIVDSSEQSRERPKESEKPEKYYSGNKKNHTFKNQIITTPKGTEIVDVIIGERGPLSDINLLNKQREKFKDNQYFQGDKEDQGAERTSTPKKKPRKKEMPEEIKEKNQQKAQKRIFVEHVIRLLKIFGIARERFRLKEKSYEKVIMVVCGLVR
>NC_008312.1|WP_011614087.1|7426400_7426775_-|DDE-transposase-family-protein
MNKTLEYIHNYPKETKRIIGITYEQLTQLIENAIIKESENLKVIDEKEIRLIKPGGGRKKTLTKTEEIFLTLYYLHHIPTFQLLGINFGFSESTANNIFHYWINILPDLLPASLLEQVKKKKMN
>NC_008312.1|WP_011614088.1|7428606_7429086_+|transposase
MMAADREFHSIFLSHWLKKYQKQDLYFVFRQKKTTIIKRGKKYCKVSELKVNFGETKLLLNHIFPKILKVGTYNLLNYKKQKYRQKSVVDKWYILSNLSSPKKIKKIYIQRMGIEAMFKYYKTGSYNLESAKANKMRLSNLILLIAISYTISSFQVQKN
>NC_008312.1|WP_155994602.1|7432119_7432284_+|hypothetical-protein
MIALTIGKVRRLCQKFGEQVSGELPERKCNSRTRFISKPTNNVGIVGALQPFVL
>NC_008312.1|WP_063823355.1|7432429_7432852_+|transposase
MDESPWLVQGVKEWMWVISSEKYSLFHAGDTRSRAKLEYLLGQSFSGVLSSDDFSVYNSYRVVAQQKCLAHLQRHFQQVTRLKQAHQKALGEAFLSWIDEAFTQHSGVKLLKHLLMLLGPNLSRCGLNRQFRLGVPKQVM

Crispr_ID: NC_008312_50

• CRISPR_ID: NC_008312_50
• CRISPR_location: 7546756-7546858
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 1 spacers

Consensus repeat of NC_008312_50

Consensus_repeat	Method
ATTTTTATTCTTTTATATTTACAGTTT	CRISPRCasFinder

spacers of NC_008312_50

>50.1|7546783|49|NC_008312|CRISPRCasFinder
CCTGAATTGCTCTGAAATTGAGATACTAAAAACTGACTTCATATTAATG

CRISPR arrays and Neighbor proteins around NC_008312_50

CRISPR arrays

The CRISPR arrays of NC_008312_50

>merge|NC_008312|50|7546756-7546858|CRISPRCasFinder
ATTTTTATTCTTTTATATTTACAGTTTCCTGAATTGCTCTGAAATTGAGATACTAAAAACTGACTTCATATTAATGATTTTTATTCTTTTATATTTACAGTTT

>NC_008312|50|40|7546756-7546858|CRISPRCasFinder
ATTTTTATTCTTTTATATTTACAGTTT	CCTGAATTGCTCTGAAATTGAGATACTAAAAACTGACTTCATATTAATG
ATTTTTATTCTTTTATATTTACAGTTT

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_008312.1|WP_011614170.1|7565851_7566799_-|ABC-transporter-permease	unknown	unknown	unknown
NC_008312.1|WP_011614156.1|7540272_7540881_+|hypothetical-protein	unknown	unknown	unknown
NC_008312.1|WP_155994751.1|7542510_7542885_+|L,D-transpeptidase-family-protein	unknown	unknown	gnl|CDD|341130
NC_008312.1|WP_044138008.1|7552349_7553351_+|hypothetical-protein	unknown	unknown	unknown
NC_008312.1|WP_044138002.1|7533288_7534638_-|cyclic-nucleotide-binding-domain-containing-protein	unknown	unknown	gnl|CDD|215625
NC_008312.1|WP_011614167.1|7559013_7563648_-|CHAT-domain-containing-protein	unknown	unknown	gnl|CDD|378942
NC_008312.1|WP_011614169.1|7564767_7565499_-|hypothetical-protein	unknown	unknown	gnl|CDD|237125
NC_008312.1|WP_044137051.1|7550165_7551692_+|FAD-dependent-oxidoreductase	unknown	unknown	gnl|CDD|223737
NC_008312.1|WP_011614171.1|7566801_7567707_-|hypothetical-protein	unknown	unknown	unknown
NC_008312.1|WP_011614159.1|7543283_7544237_+|ABC-transporter-substrate-binding-protein	unknown	unknown	gnl|CDD|238499
NC_008312.1|WP_011614168.1|7563976_7564768_-|DUF1822-family-protein	unknown	unknown	gnl|CDD|370155
NC_008312.1|WP_011614157.1|7541453_7542095_+|bifunctional-4-hydroxy-2-oxoglutarate-aldolase/2-dehydro-3-deoxy-phosphogluconate-aldolase	unknown	unknown	gnl|CDD|180985
NC_008312.1|WP_011614155.1|7537609_7538287_+|hypothetical-protein	unknown	unknown	gnl|CDD|377559
NC_008312.1|WP_011614161.1|7545482_7546301_+|metal-ABC-transporter-permease	unknown	unknown	gnl|CDD|224033
NC_008312.1|WP_011614160.1|7544233_7545034_+|metal-ABC-transporter-ATP-binding-protein	unknown	unknown	gnl|CDD|224046
NC_008312.1|WP_011610772.1|7539210_7540248_+|IS630-family-transposase	unknown	unknown	gnl|CDD|315923
NC_008312.1|WP_011614154.1|7535045_7537298_-|tetratricopeptide-repeat-protein	unknown	unknown	gnl|CDD|226428
NC_008312.1|WP_011614172.1|7570337_7571768_+|hopanoid-biosynthesis-associated-radical-SAM-protein-HpnJ	unknown	unknown	gnl|CDD|132511
NC_008312.1|WP_011614162.1|7547129_7548305_+|glycosyltransferase	unknown	unknown	gnl|CDD|132512
NC_008312.1|WP_011614163.1|7548843_7549995_+|DegT/DnrJ/EryC1/StrS-aminotransferase-family-protein	unknown	unknown	gnl|CDD|223476

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_008312.1|WP_155994751.1|7542510_7542885_+|L,D-transpeptidase-family-protein	gnl|CDD|341130	cd16913, YkuD_like, L,D-transpeptidases/carboxypeptidases similar to Bacillus YkuD. Members of the YkuD-like family of proteins are found in a range of bacteria. The best studied member Bacillus YkuD has been shown to act as an L,D-transpeptidase that gives rise to an alternative pathway for peptidoglycan cross-linking. Another member Helicobacter pylori Csd6 functions as an L,D-carboxypeptidase and regulates helical cell shape and motility. The conserved region contains a conserved histidine and cysteine, with the cysteine thought to be an active site residue.	7.39476e-37
NC_008312.1|WP_044138002.1|7533288_7534638_-|cyclic-nucleotide-binding-domain-containing-protein	gnl|CDD|215625	PLN03192, PLN03192, Voltage-dependent potassium channel; Provisional.	3.16551e-47
NC_008312.1|WP_011614167.1|7559013_7563648_-|CHAT-domain-containing-protein	gnl|CDD|378942	pfam12770, CHAT, CHAT domain. These proteins appear to be related to peptidases in peptidase clan CD that includes the caspases. This domain has been termed the CHAT domain for Caspase HetF Associated with Tprs. This family has been identified as a sister group to the separins.	3.14309e-31
NC_008312.1|WP_011614169.1|7564767_7565499_-|hypothetical-protein	gnl|CDD|237125	PRK12519, PRK12519, RNA polymerase sigma factor; Provisional.	0.000778188
NC_008312.1|WP_044137051.1|7550165_7551692_+|FAD-dependent-oxidoreductase	gnl|CDD|223737	COG0665, DadA, Glycine/D-amino acid oxidases (deaminating) [Amino acid transport and metabolism].	1.17655e-06
NC_008312.1|WP_011614159.1|7543283_7544237_+|ABC-transporter-substrate-binding-protein	gnl|CDD|238499	cd01017, AdcA, Metal binding protein AdcA. These proteins have been shown to function in the ABC uptake of Zn2+ and Mn2+ and in competence for genetic transformation and adhesion. The AdcA proteins belong to the TroA superfamily of helical backbone metal receptor proteins that share a distinct fold and ligand binding mechanism. They are comprised of two globular subdomains connected by a long alpha helix and they bind their ligand in the cleft between these domains. In addition, many of these proteins have a low complexity region containing metal binding histidine-rich motif (repetitive HDH sequence).	4.95908e-96
NC_008312.1|WP_011614168.1|7563976_7564768_-|DUF1822-family-protein	gnl|CDD|370155	pfam08852, DUF1822, Protein of unknown function (DUF1822). This family of proteins are functionally uncharacterized.	1.19417e-47
NC_008312.1|WP_011614157.1|7541453_7542095_+|bifunctional-4-hydroxy-2-oxoglutarate-aldolase/2-dehydro-3-deoxy-phosphogluconate-aldolase	gnl|CDD|180985	PRK07455, PRK07455, bifunctional 4-hydroxy-2-oxoglutarate aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase.	3.32421e-113
NC_008312.1|WP_011614155.1|7537609_7538287_+|hypothetical-protein	gnl|CDD|377559	pfam05838, Glyco_hydro_108, Glycosyl hydrolase 108. This family acts as a lysozyme (N-acetylmuramidase), EC:3.2.1.17. It contains a conserved EGGY motif near the N-terminus, the glutamic acid within this motif is essential for catalytic activity. In bacteria, it may activate the secretion of large proteins via the breaking and rearrangement of the peptidoglycan layer during secretion. It is frequently found at the N-terminus of proteins containing a C-terminal pfam09374 domain.	1.9728e-30
NC_008312.1|WP_011614161.1|7545482_7546301_+|metal-ABC-transporter-permease	gnl|CDD|224033	COG1108, ZnuB, ABC-type Mn2+/Zn2+ transport systems, permease components [Inorganic ion transport and metabolism].	2.38356e-49
NC_008312.1|WP_011614160.1|7544233_7545034_+|metal-ABC-transporter-ATP-binding-protein	gnl|CDD|224046	COG1121, ZnuC, ABC-type Mn/Zn transport systems, ATPase component [Inorganic ion transport and metabolism].	6.77682e-87
NC_008312.1|WP_011610772.1|7539210_7540248_+|IS630-family-transposase	gnl|CDD|315923	pfam13358, DDE_3, DDE superfamily endonuclease. This family of proteins are related to pfam00665 and are probably endonucleases of the DDE superfamily. Transposase proteins are necessary for efficient DNA transposition. This domain is a member of the DDE superfamily, which contain three carboxylate residues that are believed to be responsible for coordinating metal ions needed for catalysis. The catalytic activity of this enzyme involves DNA cleavage at a specific site followed by a strand transfer reaction.	9.9949e-34
NC_008312.1|WP_011614154.1|7535045_7537298_-|tetratricopeptide-repeat-protein	gnl|CDD|226428	COG3914, Spy, Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones].	1.23858e-84
NC_008312.1|WP_011614172.1|7570337_7571768_+|hopanoid-biosynthesis-associated-radical-SAM-protein-HpnJ	gnl|CDD|132511	TIGR03471, HpnJ, hopanoid biosynthesis associated radical SAM protein HpnJ. The sequences represented by this model are members of the radical SAM superfamily of enzymes (pfam04055). These enzymes utilize an iron-sulfur redox cluster and S-adenosylmethionine to carry out diverse radical mediated reactions. The member of this clade from Acidithiobacillus ferrooxidans ATCC 23270 (AFE_0975) is found in the same locus as squalene-hopene cyclase (SHC, TIGR01507) and other genes associated with the biosynthesis of hopanoid natural products. Similarly, in Ralstonia eutropha JMP134 (Reut_B4901) this gene is adjacent to HpnAB, IspH and HpnH (TIGR03470), although SHC itself is elsewhere in the genome. Notably, this gene (here named HpnJ) and three others form a conserved set (HpnIJKL) which occur in a subset of all genomes containing the SHC enzyme. This relationship was discerned using the method of partial phylogenetic profiling. This group includes Zymomonas mobilis, the organism where the initial hopanoid biosynthesis locus was described consisting of the genes HpnA-E and SHC (HpnF). Continuing past SHC are found a phosphorylase enzyme (ZMO0873, i.e. HpnG, TIGR03468) and another radical SAM enzyme (ZMO0874), HpnH. Although discontinuous in Z. mobilis, we continue the gene symbol sequence with HpnIJKL. One of the well-described hopanoid intermediates is bacteriohopanetetrol. In the conversion from hopene several reactions must occur in the side chain for which a radical mechanism might be reasonable. These include the four (presumably anaerobic) hydroxylations and a methyl shift.	0
NC_008312.1|WP_011614162.1|7547129_7548305_+|glycosyltransferase	gnl|CDD|132512	TIGR03472, HpnI, hopanoid biosynthesis associated glycosyl transferase protein HpnI. This family of genes include a glycosyl transferase, group 2 domain (pfam00535) which are responsible, generally for the transfer of nucleotide-diphosphate sugars to substrates such as polysaccharides and lipids. The member of this clade from Acidithiobacillus ferrooxidans ATCC 23270 (AFE_0974) is found in the same locus as squalene-hopene cyclase (SHC, TIGR01507) and other genes associated with the biosynthesis of hopanoid natural products. Similarly, in Ralstonia eutropha JMP134 (Reut_B4902) this gene is adjacent to HpnAB, IspH and HpnH (TIGR03470), although SHC itself is elsewhere in the genome. Notably, this gene (here named HpnI) and three others form a conserved set (HpnIJKL) which occur in a subset of all genomes containing the SHC enzyme. This relationship was discerned using the method of partial phylogenetic profiling. This group includes Zymomonas mobilis, the organism where the initial hopanoid biosynthesis locus was described consisting of the genes HpnA-E and SHC (HpnF). Continuing past SHC are found a phosphorylase enzyme (ZMO0873, i.e. HpnG, TIGR03468) and another radical SAM enzyme (ZMO0874), HpnH. Although discontinuous in Z. mobilis, we continue the gene symbol sequence with HpnIJKL. Hopanoids are known to feature polar glycosyl head groups in many organisms.	6.6567e-83
NC_008312.1|WP_011614163.1|7548843_7549995_+|DegT/DnrJ/EryC1/StrS-aminotransferase-family-protein	gnl|CDD|223476	COG0399, WecE, Predicted pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis [Cell envelope biogenesis, outer membrane].	1.50976e-112

Protein sequences

>NC_008312.1|WP_011614161.1|7545482_7546301_+|metal-ABC-transporter-permease
MNFSELISLFSLPFMQRAIIGGILLGILGGLLGGFVILRQLSLFGNALGHTAFLAVVIGALLQLPTMMVLIGFLLLFGLGINYLIQKTNLGGDTILSIVIASSVALGTIGFNFVPGYRGNLLSILFGDILAISNLDLAFVVILLVVSLSWLGVTLQKQILLTLNPELAQVQGIPVERYQYIFIIILSLAIALTIRAVGILLVNAFLVIPAATAKLICHQFVPFLGVSALIGSMSGVIGMVLSGTLNLPSGPSIVLVQLLTFLVVVFSGKGRF
>NC_008312.1|WP_011614160.1|7544233_7545034_+|metal-ABC-transporter-ATP-binding-protein
MKLVERNKSLPVITVQNLTVIIGQYKAVESVSFQIFSGSNTAIIGPNGAGKSTLIQAILGLIPYEYGYVEIIGREIKNLGKYWHKIGYIPQKLTFDRSFPLTVTELVSLGWPQRGFMKSQEKLISVEKALLKVGLQNHRKQLIGNLSGGELKRALLAYCLVQPRQLLILDEVMAGVDPNGEVEFAELLANLQAENGFSILQVSHDLDMVSSYCDQVICMNRRLLCCGKPNITLDKDNLSNIYGDNLTRYLHHHQKERFLNKTIGNS
>NC_008312.1|WP_011614159.1|7543283_7544237_+|ABC-transporter-substrate-binding-protein
MLRKFKWIGSSLLLTIALSINASAISIGKVAQNRNGIKIIATFLPIYIFTKGVAGETEEIEILIPPGTDPHEYQGTPENARSIAQADILVKNGLGLEEFLEKLVDSTGNSQLQKINASQNIEPIDMEEDDDNHNDHDHDHDHDHDHSHKEGNPHVWLDPVLAQQQVKNIRDGLIKANPNNATTYQANASIYLEKLQRLDQEFKTRLKPFKECKFIVFHDAYPYLAKRYNLQQIAVVELPQDNIKPRDIQRVIEAAKKYQVKGLLAEIGFNDSRMQQIAKDIGLPIKKLDPINSGLLDPEHYFTAMRNNLKSLEEVCQ
>NC_008312.1|WP_155994751.1|7542510_7542885_+|L,D-transpeptidase-family-protein
MLELQQSNERWISIDLSTQRLIAWEGNEAVYAVIVSTGKASTPTRLGTFQIQTKYPTTRMTGPGYDVPDVPYTMYYDAGMAIHGAYWHNMFGTPVSHGCTNVAVNHAKWLFDWASVGTPVIVHN
>NC_008312.1|WP_011614157.1|7541453_7542095_+|bifunctional-4-hydroxy-2-oxoglutarate-aldolase/2-dehydro-3-deoxy-phosphogluconate-aldolase
MDQDNWLNTLHENRIIAVIRASKMQQAWHMANAVAAGGIRIIEITWNSHQAAKLITLLRSELPNCIIGTGTLLTLEDLQKALKIGCQFVFTPHINPIMIQTAKIAAVPIIPGALSPTEIVNAWQAGANCVKIFPISAAGGVNYIKSLQGPLGEIPLIPTGGVTLENALEFIKVGAIAVGLSGKLFPKKLIITQNWQAITQQTQLIVKQISENN
>NC_008312.1|WP_011614156.1|7540272_7540881_+|hypothetical-protein
MENLLTIETVANSIVKNSPNKPSPDSVISALLEIEKQSKKEKQKYQLDQLSGHWQLCFITGTKKTRQKVGAILGKGRYIPNWVKIKLSYSSPLNTSEIPQQVKIGMVENTVEFAVLKLSLSGLTKFIDRKNILAFDFTKITVKLFGIKLYSGYIRGGKETENKFLKETVAKQAFFAYFLIKEKFIAARGRGGGLAIWRQLEH
>NC_008312.1|WP_011610772.1|7539210_7540248_+|IS630-family-transposase
MNIIDKLNDFINQTKESKEIKRALAVKMTLSGKSYHEVKELLNVSHSFISEWKNQALFHGVESLRLQYQGRQGYLKTVEKEKTIEWLRAQDYLRLSDLKNYLQEQYDVVFESNQSYYNLFKEAGISWKKTQKKNPAKNDELVEVKRKEIQEFLAKWQPEIETGKLTVFMIDECHLLWGDILGYAWGKTDERIEIAIKNEKERQTYYGALDYKTKEFLVQEYESGNTKNTIEFIKYLQKQRPGNKLAIFWDGATYHNSQEFREYLMTINQYLSEEELLINCTRFAPNAPEQNPVEDIWLQTKNFSITFYHLCSSFKVVKWLFKFFADGQIFNFPKLFQYEILPQPT
>NC_008312.1|WP_011614155.1|7537609_7538287_+|hypothetical-protein
MIWKKFNQPQLKIKFKPQIILAIISFILAVGMPISINNKIPALARTEKNYEKKLFETALSFTLYFEGGFSNHPADKGGRTYKGILQTEYNAYRRRRGLPRLDITQISDAELIEIYQDYWDNSRSATMHPSLAVVMFDTAVNFGINNSITFLQQALGLPQTGIFDPKTKKALVKGNNRNTALQIINERIIYRYKRVQEDASQMAFFYGWLARDYSLWGYVQKLKDN
>NC_008312.1|WP_011614154.1|7535045_7537298_-|tetratricopeptide-repeat-protein
MNTLPSFSISQTPNFETLIQQAELYYTQGQFSEAMGCCRQVLTLQPNWAPAYVTLANILQAQGKVSEAISVYYRAIEFNPDLSQAYINLGTMFYRQGKLEEAIANYYKAIQLQPEMAAAYWNLAKVWEHLGKSDQAIASQQKALELNPSLGGVEFNLSEGYRLAKEGKLEEAIAVWQMAIKLKPNLAEAYGQIGMILRNKGKFSEALQNLKKAIEIQPNYATAHQHLCGILRDGNNYKVAREAVNKYYQECQEMDPIMTGIYMISTYQVSGLNEIAKDRFFELETKIIENINFVKNSVEIKSLYCNFLFSIPYLRDDIKANSNVYRLVSKAYTKLVLKLKYDHYQQLSTFEFIQGQKLKIGLISSHFCRHSVGWCSLDIIRELGNLNTEIYLYSTEHLKIDDQTHKFSQAAIKLYVPKKYPEGIADAKEIIEEIQQDKVDILIDLDSLSLPINTEIFYHQPAPICISWLGFDAPYISSDNYFLCDWNTHPQDRDKYYVEKLVRMKDSFVAVSGFERIETSKTTLRKSQRIGLDQIVYLCLASGRKFNRDLVNGQVAILKQVPNSILVHKALGDIEVFQSAYHEACKAEGVSIHRVKFMPIFSTEEEHRSIYSLADILLDSYPYNGGTHTLEALWFNLPVVTYAGEQFLSRMGYSFLESLDIKLGVSWSWEEYINWGVKLGQDYNLRQEYIDSLVKSKSPENLAPLWNPKKFAQDMYGAIEKLLINGENGRNKTSSSKGINKKNSDFKPLA
>NC_008312.1|WP_044138002.1|7533288_7534638_-|cyclic-nucleotide-binding-domain-containing-protein
MPIFAPDSKFIRLWEILIVFITVYNAFLIPFRISFEKRFYGIWILLDLIGDVILIADIFLRFHLGYFEHGEYVEDKKKIAQRYFYKLLRRHLIASFPGDLIARILLPNSLFIIGLCRCPRLLRLPQFYRIFNRWETNINIEPTLIRMCKLIIFIALITHWVACGWFLIGSWESNFGESWLINKSLKSVGTRTQYINCLYWAITTLTTVGYGDITPTTEIEIIFTLMVMFLGISMYAYTIGNVSSLISNLDAAQARYREKLHQIKTYMRENKISPKLQKKIRDYYQYKWIENRDIRDYYIVEELPHPLKTKLALQLHKEVIEKVPIFQGSTSHFVEEIVIALKPEIVPPNEYIIREGNLGNEMYFIKRGLVQVFSEKTGSIYRTMEAGTFFGEISLVYEKRRTASIITLTYCELFILYKNDFKKVLEHYPDFAAHVKKIAKERYKLENKE
>NC_008312.1|WP_011614162.1|7547129_7548305_+|glycosyltransferase
MPTLVEILQIICLIPIISGCIYLILSVWTIRNFFRKTTTEINATEKFQPPVTVLKPIRGIEKNLKSNLHTITIQDWPEYQVIYSIQDPQDSALPILDELQAEVDNQKISVVIDNKQAGANGKVNNLLGAIAQARHQIIIISDSDTNLKPDYIKNIISPLSNPNVGAVCTLFKVKSAYRWFEKMELLTINADFIPSVIFAAVTGASNACLGPSIAISRSTLQELGGLESLADYLVEDYELGRRVWTSGKKMVLLPYTIDVTVDLKNWQEWWTHQVYWDQNTYLARPWPFIATILIRAVPFAILFAIVRMGDLLGLGVLGFTLALRLFSAGITLKELKDVEGFQSLYLLPLRDTFGLIFWFLALTKRTVVWRGVKYKLVDHGKMVPVSKGVGN
>NC_008312.1|WP_011614163.1|7548843_7549995_+|DegT/DnrJ/EryC1/StrS-aminotransferase-family-protein
MKVNQQIKPFYFDISNNEIQYFLLESEKILKSGQLILGKHTTEFEKAFAEYVGTKYAIAVNSGSSGLEIILRLKKVEGTTVLVPTNTNFATIASVIRAQGKVQYLDMDEKTFAPSLEMVKEAVEKGKNLSEKISGVLWVHIGGVISPEFPQIVEYCHQQGLFVLEDTAHAHGSKINGVNAGNLGDGAAFSFFPTKVMTTCEGGMITLNNEEEDYIARSLRNQGKQGMNFGGLHTDFGNSTRITEMNALLGRIHLAKLPEMLQKRQQAYELITAPLKEAGISFVSTEKMDVASNYKLIVHLPEGKNPQEVKKAMAEKEIYLGGTVYEIPCHQQPVFQGICEGQSFPYAERWCPNHICPPLTSGMTEEDAERVGKALVEVLSMFG
>NC_008312.1|WP_044137051.1|7550165_7551692_+|FAD-dependent-oxidoreductase
MTKIQASQIEYVDVVIIGGGIAGISIAEFLARHSRLSIKVLDSAPQLGTFASGKLEGWFHTGALYSGHDDAQTFINCVNSLEDLINLYSSYFSEQCNIDITETKPNFFTPAVIPNSKGWFYDRPVYLIHPNKNSPEISLSGLKSDSVYLEIQRNRVLGRLENAYGQQHNWLQNGCCLAPIYGQIEGYEGLNCSLRSSTESIDNLCRRFDHYYGLKKSNYEVIKTLDCSMNTTGIMTTLVASAMERGVTFETGVTVDKLLIDSYGKVKIKSILCHRENGFSKRLKAKLFVFTVGKGFESFLSDLQIRAKLKRSRSAMVVAQPALSDTNFVRMSTKKKFHFNHFVHNCEIGAEKFVYSLLADSSYTNDDLINEEFEVDIEPILDSAEQYFGKDQLYSRNLFSYECVKTEFISQEEQKRRYSYWIESNPNSNYLCVLPGKFSFFPTVAFQSYRRIKTLINFEEFVEKSTFVPDVKVMEEANKLIADYYPMKVIVEAQNCTAINNNLNLSNL
>NC_008312.1|WP_044138008.1|7552349_7553351_+|hypothetical-protein
MREEVKEVAVDGWVGGFEQSNPAFAYPSPDLSSLPILDNMDNIGKLERGQKILWPEFSWKTEPDQEDGKRCYRMFAPDISRLGYTNDGRIYSIICPQQGYSSPTLGSFNVEVTVTGNRGWVNEETRELAADMGVVGKIWFGPSGKDNSFVQRLKGYFERKNLSFPLNKDNAIQVKTHVPNDPGQPTFKIAQGSSTRFPIPEFAKHEGIAWALGHIEVQIGELIETGQEEVDRFNRFILDIFNLASGNMLKNGNILTWNLWFNAPELVDVDEWQGHAELWRKSLQADHGKTPEGPGTVSKYYDGTEFHPIKELLLEELPKVKAFIAEYIEGATS
>NC_008312.1|WP_011614167.1|7559013_7563648_-|CHAT-domain-containing-protein
MDNKRIEAYVNLINQLLNSPSGEVEKILEANQELVDEGLLEIMELYAQQLAENDDENAQNAANFLRHLRSQLVELLEISEYSPSTHYSSAEYFNFLEEVLEATAESKGDSKVVYPFLQQNLDKLDDNFADILRNWATAKFSEAEAGVAEYIAMCVGELSNLIQQFPLGSQANNMEISIAGYEVVLKVFTHKSHRENWATIQNNLGAAYRDRIRGDKAENIEAAIAAYQQALLVRTQTDFPMDWAGTQNNLGIAYRNRIRGDKAENIEAAIAAFQQALLVYTQTDFPINWAMTQNNLGGAYFYRIRGDKAENIEAAIAAYQQALLVYTQTDFPMDWAMTQNNLGAAYRNRIRGDKAENIEAAIAACQQALLVYTQTDFPIDWAMTQNNLGGAYFYRIRGDKAENIEAAIAAYQQALLVFTQTDFPIDWAMTQNNLGAAYSDRIRGEKAENIEAAIAACQQALLVYTQTDFPMDWAMTQNNLGAAYRDRIRGDKAENIEAAIAAFQQALLVYTQTDFPINWAMTQNNLGIAYSDRIRGDKAENIEAAIAAYQQALLVYTQTDFPMDWAMTQNNLGAAYRNRIRGDKAENIEAAIAACQQALLVRTQTDFPMDWANTQNNLGSAYGNRIKGDQAENIEAAIAAFQQALLVRTQTDFPMDWANTQNNLGIAYRDRIRGDKAENIEAAIAAYQQALLVYTQTDFPINWARTQNNLGIAYSDRIRGDKAENIEAAIAAYQQALLVRTQTDFPMEWAMTQNNLGNAYSDRIRGDKAQNIKAAIAAFQQALLVYTQTDFPINWAAAQNNLGLAYSDRIRGDKAENIEAAIAANIEAAIAAYEQALQVRTQTDFPIDWAQTQNNLGIAYSDRIRGDKAENIEAAIAAYQQALLVRTQTDFPMEWAQTQNNLGLAYIYRIRGDKAENIEAAIAAYEQALLVRTLEADPINHLQTTNNLGNLYFDNQNWQLAADNYKKAITAVELSRSWSKDDDRRQEIIEESIGVYRKIVQAYVNSDQIEKALEYVERSRSKRLVDIMASNDRYSQGEMPGEVEERLKEHEAIQQQINQLWEQQQKGSQIESKDLAVATRGRAATEARNKRIGELEAKKQEVYKKIRSFDRVLAEGIQVAPLEFPKIQALIQEPTTAILSFYTITDDTYLFVLRQDGVKVHTYEGLGLKELQNWIWEKWFGSYLSSREEWQQQMPEFLQDVSKKLKLEELCKSYLQDIEELILIPHLSLHFLPWNAMPVAESGEDKYLGDRFRIRTLASCQILDFCTEREEIQGEVKQGIVEDTHNDLPCSSYEAQYIAQMYGVPEHQRLRGEAATIDSYKLLLSQVQRLLSTHHAQSRIDNCMESALVLADGRLTLGQLLSPAFRFPDLDEVFIDCCETNFGRVQISDDVLTLNTGFLCAGARGVISSLWSVDDLGTCLFSIFYHQLRQEGKNRSLALQLGQRQLRELTGKELKKKYKKELESSLDEKLEPAYKQLQEIERRRDGYTKSSVEYQELEEEREKLVAIYERIFYTKNKYLKAACKKEHPFEHPAYWSAFICAGLS
>NC_008312.1|WP_011614168.1|7563976_7564768_-|DUF1822-family-protein
MTITDNDAINIPIPMEAHSSAQKFAAQQPNSEKKTQVYLNTLVVYAVDNFLKMMDIKTDLEASDFWNPAIRFYQNVADLVVVDRGKLECRFVLPEQDKIELPLEVFEDRIGYILVRLDQSLQFGEILGFLPMDDPEEMPEELEVDELEHIEVLFECLQRLESANSAFSAEVDPVFSRVKDRLAMDNFTNIIAQLEWIYRTKKSYEWRAATKSLFVTYLDDEKEELASNFMANLKEDDVQDRDVKLSDLAEDLINKLVKIWEGE
>NC_008312.1|WP_011614169.1|7564767_7565499_-|hypothetical-protein
MVISKYVSLTQVYNEMADNDLLCGAIANFCGETPGSQEWHRAFDVLWTGILKSKILATSQHPKYPDLLQEIQLELSQRICQEFDPKRGKNFLHSLRLWINYRKNNYGLGLRYRILDLYQEYKQKAQREASLDAPIYGGNNDLNIPTLEDVIAGNFPEPMESLSQQDFGDKLSAEVQKLGCHPKKYPQCTCGEIARRNFFMDPPQIQKDIAEELKVPLGTLTAHWNRKCKPLLRKIYQELSGEK
>NC_008312.1|WP_011614170.1|7565851_7566799_-|ABC-transporter-permease
MHNSSLGEEGQNFQSAKEDYYKKLAGWKQQDEDERERPNREIDERRSLDHIRQLASLRFKHFYKAGETRERKLETENELARLKQEYPEFLRKGIRTTLGYFFMLSFFIAVLVINFVLIKQPVEYLASQAFPPGSFAVTVAAILLPFVIVLFELGVCSQLFSAQMSPSSRDEVILWQRLANTIVWVTPAMLLGTSVALYTGEEWPPELYEIILLLAMGILAYVTDAGVVYGYDRYQNAFAFFWFRINYLRRQYKLRRYKRIFYQEKYHFTHACKNYEAAVNYHNQNFTSKVTFVPINVYFDDVYYEQLSISGKPSS
>NC_008312.1|WP_011614171.1|7566801_7567707_-|hypothetical-protein
MIVTILKIYGILIIISTILSIASCAGKVDGKTSIKTTSPIISEPLPEVKNALQNQARSTPVKVVILIDKTVSADWSRIEGPKTQDVQSSLRLLKINGGELAVGNFCDDSNRPLERVRVEQQPLLEKVVFHHPVPPVEPKNKGNAFTYRKEKDQYKQELVKYKTLRQNDLQILADHNNSVQEWHSQSEEKINEFLTTQVKPILARPVNCGSSDIQGGINRAKLFLGESDLTWRQTPQKFAVFITDGLDNVGVQPVEFKSNAEVLLVNGAGGKGIFENIEHKAFESVPAAFRYLVTQVNKGEN
>NC_008312.1|WP_011614172.1|7570337_7571768_+|hopanoid-biosynthesis-associated-radical-SAM-protein-HpnJ
MKKTLFLNPPSFDGFDGGAGARYQAKREITSFWYPTWLAQPAALVPGSKLVDAPAHYQTVEDVLKIAKDYELVIMHTSTPSLPNDIKCAEAIKNQNPETKIGFVGAHVAVLPEKTLKDHPIIDFVCRNEFDYTCKELSQGKPFAKIKGLSYYDTQGNIHHTPERELIHDWDAMPSVFPVYAEHLNIRNYLIGYLLNPYISLYTGRGCPAKCTFCLWPQTIGGHQYRAKSPEAVGREMAEAKAIWGSSVREYFFDDDTFTIDKKRAIAISEHLQRLKLTWSCNARGNLDYNTLKELKKNGLRLLLVGFESGNQKILDGVNKGIKLEVARKFMENCHKLGIKVHGAFILGLPNESQETIEETIRFACEVNPHTIQVSIASPYPGTELYTQAEKNGWFTGDSLVASSGIQMSALQYPHLSGSEIEDGVEQMYRRFYFRPKSIIPIVGEMLADPQMLVRRLREGKEFLSYLRERHQRALT

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity
NC_008312_3	3.22|614119|29|NC_008312|CRT	614119-614147	29	NC_008312.1	617767-617795	0	1.0
NC_008312_3	3.24|614218|29|NC_008312|CRT	614218-614246	29	NC_008312.1	616948-616976	0	1.0
NC_008312_3	3.24|614218|29|NC_008312|CRT	614218-614246	29	NC_008312.1	617533-617561	0	1.0
NC_008312_3	3.25|614272|29|NC_008312|CRT	614272-614300	29	NC_008312.1	617002-617030	0	1.0
NC_008312_3	3.27|614371|38|NC_008312|CRT	614371-614408	38	NC_008312.1	617767-617804	0	1.0
NC_008312_3	3.32|614668|20|NC_008312|CRT	614668-614687	20	NC_008312.1	617488-617507	0	1.0
NC_008312_3	3.32|614668|20|NC_008312|CRT	614668-614687	20	NC_008312.1	617677-617696	0	1.0
NC_008312_3	3.32|614668|20|NC_008312|CRT	614668-614687	20	NC_008312.1	617830-617849	0	1.0
NC_008312_3	3.32|614668|20|NC_008312|CRT	614668-614687	20	NC_008312.1	617866-617885	0	1.0
NC_008312_3	3.33|614713|29|NC_008312|CRT	614713-614741	29	NC_008312.1	616948-616976	0	1.0
NC_008312_3	3.33|614713|29|NC_008312|CRT	614713-614741	29	NC_008312.1	617533-617561	0	1.0
NC_008312_3	3.35|614830|29|NC_008312|CRT	614830-614858	29	NC_008312.1	617092-617120	0	1.0
NC_008312_3	3.35|614830|29|NC_008312|CRT	614830-614858	29	NC_008312.1	617596-617624	0	1.0
NC_008312_3	3.36|614884|29|NC_008312|CRT	614884-614912	29	NC_008312.1	617002-617030	0	1.0
NC_008312_3	3.38|614983|38|NC_008312|CRT	614983-615020	38	NC_008312.1	617767-617804	0	1.0
NC_008312_3	3.42|615217|38|NC_008312|CRT	615217-615254	38	NC_008312.1	617767-617804	0	1.0
NC_008312_3	3.45|615433|29|NC_008312|CRT	615433-615461	29	NC_008312.1	617092-617120	0	1.0
NC_008312_3	3.45|615433|29|NC_008312|CRT	615433-615461	29	NC_008312.1	617596-617624	0	1.0
NC_008312_3	3.46|615487|29|NC_008312|CRT	615487-615515	29	NC_008312.1	617002-617030	0	1.0
NC_008312_3	3.48|615586|20|NC_008312|CRT	615586-615605	20	NC_008312.1	617488-617507	0	1.0
NC_008312_3	3.48|615586|20|NC_008312|CRT	615586-615605	20	NC_008312.1	617677-617696	0	1.0
NC_008312_3	3.48|615586|20|NC_008312|CRT	615586-615605	20	NC_008312.1	617830-617849	0	1.0
NC_008312_3	3.48|615586|20|NC_008312|CRT	615586-615605	20	NC_008312.1	617866-617885	0	1.0
NC_008312_3	3.49|615631|38|NC_008312|CRT	615631-615668	38	NC_008312.1	617533-617570	0	1.0
NC_008312_3	3.56|616237|38|NC_008312|CRT	616237-616274	38	NC_008312.1	617101-617138	0	1.0
NC_008312_4	4.1|617200|20|NC_008312|CRT	617200-617219	20	NC_008312.1	616957-616976	0	1.0
NC_008312_4	4.1|617200|20|NC_008312|CRT	617200-617219	20	NC_008312.1	617542-617561	0	1.0
NC_008312_4	4.1|617200|20|NC_008312|CRT	617200-617219	20	NC_008312.1	617776-617795	0	1.0
NC_008312_4	4.3|617317|29|NC_008312|CRT	617317-617345	29	NC_008312.1	617767-617795	0	1.0
NC_008312_4	4.4|617380|20|NC_008312|CRT	617380-617399	20	NC_008312.1	617641-617660	0	1.0
NC_008312_4	4.5|617434|29|NC_008312|CRT	617434-617462	29	NC_008312.1	617767-617795	0	1.0
NC_008312_14	14.1|1851536|16|NC_008312|CRISPRCasFinder	1851536-1851551	16	NC_008312.1	1851620-1851635	0	1.0
NC_008312_14	14.1|1851536|16|NC_008312|CRISPRCasFinder	1851536-1851551	16	NC_008312.1	6468189-6468204	0	1.0
NC_008312_14	14.1|1851536|16|NC_008312|CRISPRCasFinder	1851536-1851551	16	NC_008312.1	6468237-6468252	0	1.0
NC_008312_14	14.1|1851536|16|NC_008312|CRISPRCasFinder	1851536-1851551	16	NC_008312.1	6468249-6468264	0	1.0
NC_008312_14	14.1|1851536|16|NC_008312|CRISPRCasFinder	1851536-1851551	16	NC_008312.1	6468261-6468276	0	1.0
NC_008312_14	14.1|1851536|16|NC_008312|CRISPRCasFinder	1851536-1851551	16	NC_008312.1	6468273-6468288	0	1.0
NC_008312_14	14.1|1851536|16|NC_008312|CRISPRCasFinder	1851536-1851551	16	NC_008312.1	6468285-6468300	0	1.0
NC_008312_21	21.32|2628710|26|NC_008312|CRT	2628710-2628735	26	NC_008312.1	2631433-2631458	0	1.0
NC_008312_21	21.39|2629023|19|NC_008312|CRT	2629023-2629041	19	NC_008312.1	2627131-2627149	0	1.0
NC_008312_21	21.41|2629118|25|NC_008312|CRT	2629118-2629142	25	NC_008312.1	2627125-2627149	0	1.0
NC_008312_21	21.43|2629205|19|NC_008312|CRT	2629205-2629223	19	NC_008312.1	2627131-2627149	0	1.0
NC_008312_21	21.45|2629300|25|NC_008312|CRT	2629300-2629324	25	NC_008312.1	2627125-2627149	0	1.0
NC_008312_21	21.79|2631121|19|NC_008312|CRT	2631121-2631139	19	NC_008312.1	2627131-2627149	0	1.0
NC_008312_33	33.1|4206516|31|NC_008312|CRISPRCasFinder	4206516-4206546	31	NC_008312.1	4208808-4208838	0	1.0
NC_008312_45	45.1|6864494|18|NC_008312|CRT	6864494-6864511	18	NC_008312.1	6864878-6864895	0	1.0
NC_008312_3	3.5|613147|20|NC_008312|CRT	613147-613166	20	NC_008312.1	616912-616931	1	0.95
NC_008312_3	3.5|613147|20|NC_008312|CRT	613147-613166	20	NC_008312.1	617497-617516	1	0.95
NC_008312_3	3.12|613408|38|NC_008312|CRT	613408-613445	38	NC_008312.1	617533-617570	1	0.974
NC_008312_3	3.15|613633|38|NC_008312|CRT	613633-613670	38	NC_008312.1	617767-617804	1	0.974
NC_008312_3	3.17|613777|47|NC_008312|CRT	613777-613823	47	NC_008312.1	617092-617138	1	0.979
NC_008312_3	3.17|613777|47|NC_008312|CRT	613777-613823	47	NC_008312.1	617767-617813	1	0.979
NC_008312_3	3.27|614371|38|NC_008312|CRT	614371-614408	38	NC_008312.1	616849-616886	1	0.974
NC_008312_3	3.28|614434|20|NC_008312|CRT	614434-614453	20	NC_008312.1	617146-617165	1	0.95
NC_008312_3	3.38|614983|38|NC_008312|CRT	614983-615020	38	NC_008312.1	616849-616886	1	0.974
NC_008312_3	3.39|615046|20|NC_008312|CRT	615046-615065	20	NC_008312.1	617146-617165	1	0.95
NC_008312_3	3.42|615217|38|NC_008312|CRT	615217-615254	38	NC_008312.1	616849-616886	1	0.974
NC_008312_3	3.49|615631|38|NC_008312|CRT	615631-615668	38	NC_008312.1	616948-616985	1	0.974
NC_008312_3	3.56|616237|38|NC_008312|CRT	616237-616274	38	NC_008312.1	617542-617579	1	0.974
NC_008312_3	3.62|616750|47|NC_008312|CRT	616750-616796	47	NC_008312.1	617056-617102	1	0.979
NC_008312_3	3.63|616822|38|NC_008312|CRT	616822-616859	38	NC_008312.1	617065-617102	1	0.974
NC_008312_4	4.2|617254|29|NC_008312|CRT	617254-617282	29	NC_008312.1	617632-617660	1	0.966
NC_008312_10	10.1|1399212|19|NC_008312|CRISPRCasFinder	1399212-1399230	19	NC_008312.1	3181536-3181554	1	0.947
NC_008312_21	21.23|2628331|40|NC_008312|CRT	2628331-2628370	40	NC_008312.1	2631433-2631472	1	0.975
NC_008312_21	21.27|2628512|19|NC_008312|CRT	2628512-2628530	19	NC_008312.1	3958059-3958077	1	0.947
NC_008312_21	21.29|2628592|19|NC_008312|CRT	2628592-2628610	19	NC_008312.1	3958059-3958077	1	0.947
NC_008312_23	23.1|2941370|38|NC_008312|CRT	2941370-2941407	38	NC_008312.1	2941312-2941349	1	0.974
NC_008312_23	23.1|2941370|38|NC_008312|CRT	2941370-2941407	38	NC_008312.1	3331256-3331293	1	0.974
NC_008312_23	23.1|2941370|38|NC_008312|CRT	2941370-2941407	38	NC_008312.1	3331510-3331547	1	0.974
NC_008312_33	33.1|4206516|31|NC_008312|CRISPRCasFinder	4206516-4206546	31	NC_008312.1	4206720-4206750	1	0.968
NC_008312_33	33.1|4206516|31|NC_008312|CRISPRCasFinder	4206516-4206546	31	NC_008312.1	4206924-4206954	1	0.968
NC_008312_33	33.1|4206516|31|NC_008312|CRISPRCasFinder	4206516-4206546	31	NC_008312.1	4207128-4207158	1	0.968
NC_008312_33	33.1|4206516|31|NC_008312|CRISPRCasFinder	4206516-4206546	31	NC_008312.1	4207788-4207818	1	0.968
NC_008312_33	33.1|4206516|31|NC_008312|CRISPRCasFinder	4206516-4206546	31	NC_008312.1	4207992-4208022	1	0.968
NC_008312_33	33.1|4206516|31|NC_008312|CRISPRCasFinder	4206516-4206546	31	NC_008312.1	4208196-4208226	1	0.968
NC_008312_33	33.1|4206516|31|NC_008312|CRISPRCasFinder	4206516-4206546	31	NC_008312.1	4208604-4208634	1	0.968
NC_008312_33	33.1|4206516|31|NC_008312|CRISPRCasFinder	4206516-4206546	31	NC_008312.1	4209012-4209042	1	0.968
NC_008312_3	3.2|613003|20|NC_008312|CRT	613003-613022	20	NC_008312.1	616948-616967	2	0.9
NC_008312_3	3.2|613003|20|NC_008312|CRT	613003-613022	20	NC_008312.1	617533-617552	2	0.9
NC_008312_3	3.4|613093|29|NC_008312|CRT	613093-613121	29	NC_008312.1	616948-616976	2	0.931
NC_008312_3	3.4|613093|29|NC_008312|CRT	613093-613121	29	NC_008312.1	617533-617561	2	0.931
NC_008312_3	3.5|613147|20|NC_008312|CRT	613147-613166	20	NC_008312.1	617155-617174	2	0.9
NC_008312_3	3.5|613147|20|NC_008312|CRT	613147-613166	20	NC_008312.1	617686-617705	2	0.9
NC_008312_3	3.5|613147|20|NC_008312|CRT	613147-613166	20	NC_008312.1	617839-617858	2	0.9
NC_008312_3	3.12|613408|38|NC_008312|CRT	613408-613445	38	NC_008312.1	616948-616985	2	0.947
NC_008312_3	3.15|613633|38|NC_008312|CRT	613633-613670	38	NC_008312.1	616849-616886	2	0.947
NC_008312_3	3.17|613777|47|NC_008312|CRT	613777-613823	47	NC_008312.1	616849-616895	2	0.957
NC_008312_3	3.26|614326|20|NC_008312|CRT	614326-614345	20	NC_008312.1	617488-617507	2	0.9
NC_008312_3	3.26|614326|20|NC_008312|CRT	614326-614345	20	NC_008312.1	617677-617696	2	0.9
NC_008312_3	3.26|614326|20|NC_008312|CRT	614326-614345	20	NC_008312.1	617830-617849	2	0.9
NC_008312_3	3.26|614326|20|NC_008312|CRT	614326-614345	20	NC_008312.1	617866-617885	2	0.9
NC_008312_3	3.27|614371|38|NC_008312|CRT	614371-614408	38	NC_008312.1	617092-617129	2	0.947
NC_008312_3	3.27|614371|38|NC_008312|CRT	614371-614408	38	NC_008312.1	617596-617633	2	0.947
NC_008312_3	3.37|614938|20|NC_008312|CRT	614938-614957	20	NC_008312.1	617488-617507	2	0.9
NC_008312_3	3.37|614938|20|NC_008312|CRT	614938-614957	20	NC_008312.1	617677-617696	2	0.9
NC_008312_3	3.37|614938|20|NC_008312|CRT	614938-614957	20	NC_008312.1	617830-617849	2	0.9
NC_008312_3	3.37|614938|20|NC_008312|CRT	614938-614957	20	NC_008312.1	617866-617885	2	0.9
NC_008312_3	3.38|614983|38|NC_008312|CRT	614983-615020	38	NC_008312.1	617092-617129	2	0.947
NC_008312_3	3.38|614983|38|NC_008312|CRT	614983-615020	38	NC_008312.1	617596-617633	2	0.947
NC_008312_3	3.42|615217|38|NC_008312|CRT	615217-615254	38	NC_008312.1	617092-617129	2	0.947
NC_008312_3	3.42|615217|38|NC_008312|CRT	615217-615254	38	NC_008312.1	617596-617633	2	0.947
NC_008312_3	3.47|615541|20|NC_008312|CRT	615541-615560	20	NC_008312.1	617488-617507	2	0.9
NC_008312_3	3.47|615541|20|NC_008312|CRT	615541-615560	20	NC_008312.1	617677-617696	2	0.9
NC_008312_3	3.47|615541|20|NC_008312|CRT	615541-615560	20	NC_008312.1	617830-617849	2	0.9
NC_008312_3	3.47|615541|20|NC_008312|CRT	615541-615560	20	NC_008312.1	617866-617885	2	0.9
NC_008312_3	3.56|616237|38|NC_008312|CRT	616237-616274	38	NC_008312.1	616858-616895	2	0.947
NC_008312_3	3.56|616237|38|NC_008312|CRT	616237-616274	38	NC_008312.1	616957-616994	2	0.947
NC_008312_3	3.56|616237|38|NC_008312|CRT	616237-616274	38	NC_008312.1	617776-617813	2	0.947
NC_008312_4	4.4|617380|20|NC_008312|CRT	617380-617399	20	NC_008312.1	617146-617165	2	0.9
NC_008312_10	10.1|1399212|19|NC_008312|CRISPRCasFinder	1399212-1399230	19	NC_008312.1	312968-312986	2	0.895
NC_008312_10	10.1|1399212|19|NC_008312|CRISPRCasFinder	1399212-1399230	19	NC_008312.1	2082368-2082386	2	0.895
NC_008312_10	10.1|1399212|19|NC_008312|CRISPRCasFinder	1399212-1399230	19	NC_008312.1	2267182-2267200	2	0.895
NC_008312_10	10.1|1399212|19|NC_008312|CRISPRCasFinder	1399212-1399230	19	NC_008312.1	2825631-2825649	2	0.895
NC_008312_10	10.1|1399212|19|NC_008312|CRISPRCasFinder	1399212-1399230	19	NC_008312.1	3001789-3001807	2	0.895
NC_008312_10	10.1|1399212|19|NC_008312|CRISPRCasFinder	1399212-1399230	19	NC_008312.1	4961158-4961176	2	0.895
NC_008312_10	10.1|1399212|19|NC_008312|CRISPRCasFinder	1399212-1399230	19	NC_008312.1	6605857-6605875	2	0.895
NC_008312_10	10.1|1399212|19|NC_008312|CRISPRCasFinder	1399212-1399230	19	NC_008312.1	7534704-7534722	2	0.895
NC_008312_17	17.1|1941253|35|NC_008312|CRISPRCasFinder	1941253-1941287	35	NC_008312.1	7654959-7654993	2	0.943
NC_008312_21	21.1|2627152|26|NC_008312|CRT	2627152-2627177	26	NC_008312.1	2631447-2631472	2	0.923
NC_008312_21	21.1|2627152|26|NC_008312|CRT	2627152-2627177	26	NC_008312.1	2941890-2941915	2	0.923
NC_008312_21	21.6|2627443|25|NC_008312|CRT	2627443-2627467	25	NC_008312.1	848634-848658	2	0.92
NC_008312_21	21.6|2627443|25|NC_008312|CRT	2627443-2627467	25	NC_008312.1	1538289-1538313	2	0.92
NC_008312_21	21.6|2627443|25|NC_008312|CRT	2627443-2627467	25	NC_008312.1	1538848-1538872	2	0.92
NC_008312_21	21.6|2627443|25|NC_008312|CRT	2627443-2627467	25	NC_008312.1	2705216-2705240	2	0.92
NC_008312_21	21.6|2627443|25|NC_008312|CRT	2627443-2627467	25	NC_008312.1	2705223-2705247	2	0.92
NC_008312_21	21.6|2627443|25|NC_008312|CRT	2627443-2627467	25	NC_008312.1	2941325-2941349	2	0.92
NC_008312_21	21.6|2627443|25|NC_008312|CRT	2627443-2627467	25	NC_008312.1	2941883-2941907	2	0.92
NC_008312_21	21.6|2627443|25|NC_008312|CRT	2627443-2627467	25	NC_008312.1	3331256-3331280	2	0.92
NC_008312_21	21.6|2627443|25|NC_008312|CRT	2627443-2627467	25	NC_008312.1	3331263-3331287	2	0.92
NC_008312_21	21.6|2627443|25|NC_008312|CRT	2627443-2627467	25	NC_008312.1	3331510-3331534	2	0.92
NC_008312_21	21.6|2627443|25|NC_008312|CRT	2627443-2627467	25	NC_008312.1	3331517-3331541	2	0.92
NC_008312_21	21.6|2627443|25|NC_008312|CRT	2627443-2627467	25	NC_008312.1	3331806-3331830	2	0.92
NC_008312_21	21.6|2627443|25|NC_008312|CRT	2627443-2627467	25	NC_008312.1	3375636-3375660	2	0.92
NC_008312_21	21.6|2627443|25|NC_008312|CRT	2627443-2627467	25	NC_008312.1	4271750-4271774	2	0.92
NC_008312_21	21.6|2627443|25|NC_008312|CRT	2627443-2627467	25	NC_008312.1	5423269-5423293	2	0.92
NC_008312_21	21.6|2627443|25|NC_008312|CRT	2627443-2627467	25	NC_008312.1	7558976-7559000	2	0.92
NC_008312_21	21.9|2627587|19|NC_008312|CRT	2627587-2627605	19	NC_008312.1	2941869-2941887	2	0.895
NC_008312_21	21.9|2627587|19|NC_008312|CRT	2627587-2627605	19	NC_008312.1	7158754-7158772	2	0.895
NC_008312_21	21.10|2627624|26|NC_008312|CRT	2627624-2627649	26	NC_008312.1	2941341-2941366	2	0.923
NC_008312_21	21.20|2628213|19|NC_008312|CRT	2628213-2628231	19	NC_008312.1	1922549-1922567	2	0.895
NC_008312_21	21.20|2628213|19|NC_008312|CRT	2628213-2628231	19	NC_008312.1	4987966-4987984	2	0.895
NC_008312_21	21.20|2628213|19|NC_008312|CRT	2628213-2628231	19	NC_008312.1	5832720-5832738	2	0.895
NC_008312_21	21.20|2628213|19|NC_008312|CRT	2628213-2628231	19	NC_008312.1	7325462-7325480	2	0.895
NC_008312_21	21.22|2628294|19|NC_008312|CRT	2628294-2628312	19	NC_008312.1	4987966-4987984	2	0.895
NC_008312_21	21.22|2628294|19|NC_008312|CRT	2628294-2628312	19	NC_008312.1	7325462-7325480	2	0.895
NC_008312_21	21.26|2628475|19|NC_008312|CRT	2628475-2628493	19	NC_008312.1	1922549-1922567	2	0.895
NC_008312_21	21.26|2628475|19|NC_008312|CRT	2628475-2628493	19	NC_008312.1	4987966-4987984	2	0.895
NC_008312_21	21.26|2628475|19|NC_008312|CRT	2628475-2628493	19	NC_008312.1	5832720-5832738	2	0.895
NC_008312_21	21.26|2628475|19|NC_008312|CRT	2628475-2628493	19	NC_008312.1	7325462-7325480	2	0.895
NC_008312_21	21.30|2628629|19|NC_008312|CRT	2628629-2628647	19	NC_008312.1	1282036-1282054	2	0.895
NC_008312_21	21.30|2628629|19|NC_008312|CRT	2628629-2628647	19	NC_008312.1	1993335-1993353	2	0.895
NC_008312_21	21.33|2628754|19|NC_008312|CRT	2628754-2628772	19	NC_008312.1	2698721-2698739	2	0.895
NC_008312_21	21.39|2629023|19|NC_008312|CRT	2629023-2629041	19	NC_008312.1	2396366-2396384	2	0.895
NC_008312_21	21.43|2629205|19|NC_008312|CRT	2629205-2629223	19	NC_008312.1	2396366-2396384	2	0.895
NC_008312_21	21.56|2630042|25|NC_008312|CRT	2630042-2630066	25	NC_008312.1	2627125-2627149	2	0.92
NC_008312_21	21.64|2630418|19|NC_008312|CRT	2630418-2630436	19	NC_008312.1	2698721-2698739	2	0.895
NC_008312_21	21.71|2630759|19|NC_008312|CRT	2630759-2630777	19	NC_008312.1	2698721-2698739	2	0.895
NC_008312_21	21.76|2630998|19|NC_008312|CRT	2630998-2631016	19	NC_008312.1	2698721-2698739	2	0.895
NC_008312_21	21.77|2631035|25|NC_008312|CRT	2631035-2631059	25	NC_008312.1	2941335-2941359	2	0.92
NC_008312_21	21.78|2631078|25|NC_008312|CRT	2631078-2631102	25	NC_008312.1	2627125-2627149	2	0.92
NC_008312_21	21.79|2631121|19|NC_008312|CRT	2631121-2631139	19	NC_008312.1	2396366-2396384	2	0.895
NC_008312_21	21.83|2631303|19|NC_008312|CRT	2631303-2631321	19	NC_008312.1	2941341-2941359	2	0.895
NC_008312_21	21.83|2631303|19|NC_008312|CRT	2631303-2631321	19	NC_008312.1	5816713-5816731	2	0.895
NC_008312_23	23.1|2941370|38|NC_008312|CRT	2941370-2941407	38	NC_008312.1	2705217-2705254	2	0.947
NC_008312_23	23.1|2941370|38|NC_008312|CRT	2941370-2941407	38	NC_008312.1	3331228-3331265	2	0.947
NC_008312_23	23.1|2941370|38|NC_008312|CRT	2941370-2941407	38	NC_008312.1	3331235-3331272	2	0.947
NC_008312_23	23.1|2941370|38|NC_008312|CRT	2941370-2941407	38	NC_008312.1	3331242-3331279	2	0.947
NC_008312_23	23.1|2941370|38|NC_008312|CRT	2941370-2941407	38	NC_008312.1	3331249-3331286	2	0.947
NC_008312_23	23.1|2941370|38|NC_008312|CRT	2941370-2941407	38	NC_008312.1	3331263-3331300	2	0.947
NC_008312_23	23.1|2941370|38|NC_008312|CRT	2941370-2941407	38	NC_008312.1	3331270-3331307	2	0.947
NC_008312_23	23.1|2941370|38|NC_008312|CRT	2941370-2941407	38	NC_008312.1	3331277-3331314	2	0.947
NC_008312_23	23.1|2941370|38|NC_008312|CRT	2941370-2941407	38	NC_008312.1	3331369-3331406	2	0.947
NC_008312_23	23.1|2941370|38|NC_008312|CRT	2941370-2941407	38	NC_008312.1	3331383-3331420	2	0.947
NC_008312_23	23.1|2941370|38|NC_008312|CRT	2941370-2941407	38	NC_008312.1	3331390-3331427	2	0.947
NC_008312_23	23.1|2941370|38|NC_008312|CRT	2941370-2941407	38	NC_008312.1	3331496-3331533	2	0.947
NC_008312_23	23.1|2941370|38|NC_008312|CRT	2941370-2941407	38	NC_008312.1	3331503-3331540	2	0.947
NC_008312_23	23.1|2941370|38|NC_008312|CRT	2941370-2941407	38	NC_008312.1	3331665-3331702	2	0.947
NC_008312_23	23.1|2941370|38|NC_008312|CRT	2941370-2941407	38	NC_008312.1	3331686-3331723	2	0.947
NC_008312_29	29.1|3671521|26|NC_008312|CRISPRCasFinder	3671521-3671546	26	NC_008312.1	3671479-3671504	2	0.923
NC_008312_3	3.43|615280|65|NC_008312|CRT	615280-615344	65	NC_008312.1	616912-616976	5	0.923
NC_008312_3	3.43|615280|65|NC_008312|CRT	615280-615344	65	NC_008312.1	617497-617561	5	0.923
NC_008312_3	3.43|615280|65|NC_008312|CRT	615280-615344	65	NC_008312.1	617155-617219	6	0.908
NC_008312_3	3.51|615775|74|NC_008312|CRT	615775-615848	74	NC_008312.1	616912-616985	15	0.797
NC_008312_3	3.51|615775|74|NC_008312|CRT	615775-615848	74	NC_008312.1	617497-617570	15	0.797
NC_008312_3	3.58|616381|74|NC_008312|CRT	616381-616454	74	NC_008312.1	616912-616985	15	0.797

1. spacer 3.22|614119|29|NC_008312|CRT matches to position: 617767-617795, mismatch: 0, identity: 1.0

caagaccaggaacaccatcagctccagcc	CRISPR spacer
caagaccaggaacaccatcagctccagcc	Protospacer
*****************************

2. spacer 3.24|614218|29|NC_008312|CRT matches to position: 616948-616976, mismatch: 0, identity: 1.0

taagaccaggaacaccatcagctccagcc	CRISPR spacer
taagaccaggaacaccatcagctccagcc	Protospacer
*****************************

3. spacer 3.24|614218|29|NC_008312|CRT matches to position: 617533-617561, mismatch: 0, identity: 1.0

taagaccaggaacaccatcagctccagcc	CRISPR spacer
taagaccaggaacaccatcagctccagcc	Protospacer
*****************************

4. spacer 3.25|614272|29|NC_008312|CRT matches to position: 617002-617030, mismatch: 0, identity: 1.0

ccggaccaggggctccagttagacctata	CRISPR spacer
ccggaccaggggctccagttagacctata	Protospacer
*****************************

5. spacer 3.27|614371|38|NC_008312|CRT matches to position: 617767-617804, mismatch: 0, identity: 1.0

caagaccaggaacaccatcagctccagccggacccaca	CRISPR spacer
caagaccaggaacaccatcagctccagccggacccaca	Protospacer
**************************************

6. spacer 3.32|614668|20|NC_008312|CRT matches to position: 617488-617507, mismatch: 0, identity: 1.0

caggaccaggggcaccactt	CRISPR spacer
caggaccaggggcaccactt	Protospacer
********************

7. spacer 3.32|614668|20|NC_008312|CRT matches to position: 617677-617696, mismatch: 0, identity: 1.0

caggaccaggggcaccactt	CRISPR spacer
caggaccaggggcaccactt	Protospacer
********************

8. spacer 3.32|614668|20|NC_008312|CRT matches to position: 617830-617849, mismatch: 0, identity: 1.0

caggaccaggggcaccactt	CRISPR spacer
caggaccaggggcaccactt	Protospacer
********************

9. spacer 3.32|614668|20|NC_008312|CRT matches to position: 617866-617885, mismatch: 0, identity: 1.0

caggaccaggggcaccactt	CRISPR spacer
caggaccaggggcaccactt	Protospacer
********************

10. spacer 3.33|614713|29|NC_008312|CRT matches to position: 616948-616976, mismatch: 0, identity: 1.0

taagaccaggaacaccatcagctccagcc	CRISPR spacer
taagaccaggaacaccatcagctccagcc	Protospacer
*****************************

11. spacer 3.33|614713|29|NC_008312|CRT matches to position: 617533-617561, mismatch: 0, identity: 1.0

taagaccaggaacaccatcagctccagcc	CRISPR spacer
taagaccaggaacaccatcagctccagcc	Protospacer
*****************************

12. spacer 3.35|614830|29|NC_008312|CRT matches to position: 617092-617120, mismatch: 0, identity: 1.0

caagaccaggaacaccatcagctccagct	CRISPR spacer
caagaccaggaacaccatcagctccagct	Protospacer
*****************************

13. spacer 3.35|614830|29|NC_008312|CRT matches to position: 617596-617624, mismatch: 0, identity: 1.0

caagaccaggaacaccatcagctccagct	CRISPR spacer
caagaccaggaacaccatcagctccagct	Protospacer
*****************************

14. spacer 3.36|614884|29|NC_008312|CRT matches to position: 617002-617030, mismatch: 0, identity: 1.0

ccggaccaggggctccagttagacctata	CRISPR spacer
ccggaccaggggctccagttagacctata	Protospacer
*****************************

15. spacer 3.38|614983|38|NC_008312|CRT matches to position: 617767-617804, mismatch: 0, identity: 1.0

caagaccaggaacaccatcagctccagccggacccaca	CRISPR spacer
caagaccaggaacaccatcagctccagccggacccaca	Protospacer
**************************************

16. spacer 3.42|615217|38|NC_008312|CRT matches to position: 617767-617804, mismatch: 0, identity: 1.0

caagaccaggaacaccatcagctccagccggacccaca	CRISPR spacer
caagaccaggaacaccatcagctccagccggacccaca	Protospacer
**************************************

17. spacer 3.45|615433|29|NC_008312|CRT matches to position: 617092-617120, mismatch: 0, identity: 1.0

caagaccaggaacaccatcagctccagct	CRISPR spacer
caagaccaggaacaccatcagctccagct	Protospacer
*****************************

18. spacer 3.45|615433|29|NC_008312|CRT matches to position: 617596-617624, mismatch: 0, identity: 1.0

caagaccaggaacaccatcagctccagct	CRISPR spacer
caagaccaggaacaccatcagctccagct	Protospacer
*****************************

19. spacer 3.46|615487|29|NC_008312|CRT matches to position: 617002-617030, mismatch: 0, identity: 1.0

ccggaccaggggctccagttagacctata	CRISPR spacer
ccggaccaggggctccagttagacctata	Protospacer
*****************************

20. spacer 3.48|615586|20|NC_008312|CRT matches to position: 617488-617507, mismatch: 0, identity: 1.0

caggaccaggggcaccactt	CRISPR spacer
caggaccaggggcaccactt	Protospacer
********************

21. spacer 3.48|615586|20|NC_008312|CRT matches to position: 617677-617696, mismatch: 0, identity: 1.0

caggaccaggggcaccactt	CRISPR spacer
caggaccaggggcaccactt	Protospacer
********************

22. spacer 3.48|615586|20|NC_008312|CRT matches to position: 617830-617849, mismatch: 0, identity: 1.0

caggaccaggggcaccactt	CRISPR spacer
caggaccaggggcaccactt	Protospacer
********************

23. spacer 3.48|615586|20|NC_008312|CRT matches to position: 617866-617885, mismatch: 0, identity: 1.0

caggaccaggggcaccactt	CRISPR spacer
caggaccaggggcaccactt	Protospacer
********************

24. spacer 3.49|615631|38|NC_008312|CRT matches to position: 617533-617570, mismatch: 0, identity: 1.0

taagaccaggaacaccatcagctccagccggacctaca	CRISPR spacer
taagaccaggaacaccatcagctccagccggacctaca	Protospacer
**************************************

25. spacer 3.56|616237|38|NC_008312|CRT matches to position: 617101-617138, mismatch: 0, identity: 1.0

gaacaccatcagctccagctggacctacaggacctatt	CRISPR spacer
gaacaccatcagctccagctggacctacaggacctatt	Protospacer
**************************************

26. spacer 4.1|617200|20|NC_008312|CRT matches to position: 616957-616976, mismatch: 0, identity: 1.0

gaacaccatcagctccagcc	CRISPR spacer
gaacaccatcagctccagcc	Protospacer
********************

27. spacer 4.1|617200|20|NC_008312|CRT matches to position: 617542-617561, mismatch: 0, identity: 1.0

gaacaccatcagctccagcc	CRISPR spacer
gaacaccatcagctccagcc	Protospacer
********************

28. spacer 4.1|617200|20|NC_008312|CRT matches to position: 617776-617795, mismatch: 0, identity: 1.0

gaacaccatcagctccagcc	CRISPR spacer
gaacaccatcagctccagcc	Protospacer
********************

29. spacer 4.3|617317|29|NC_008312|CRT matches to position: 617767-617795, mismatch: 0, identity: 1.0

caagaccaggaacaccatcagctccagcc	CRISPR spacer
caagaccaggaacaccatcagctccagcc	Protospacer
*****************************

30. spacer 4.4|617380|20|NC_008312|CRT matches to position: 617641-617660, mismatch: 0, identity: 1.0

cgggaccaggagctccagtt	CRISPR spacer
cgggaccaggagctccagtt	Protospacer
********************

31. spacer 4.5|617434|29|NC_008312|CRT matches to position: 617767-617795, mismatch: 0, identity: 1.0

caagaccaggaacaccatcagctccagcc	CRISPR spacer
caagaccaggaacaccatcagctccagcc	Protospacer
*****************************

32. spacer 14.1|1851536|16|NC_008312|CRISPRCasFinder matches to position: 1851620-1851635, mismatch: 0, identity: 1.0

tctggtgttggttctg	CRISPR spacer
tctggtgttggttctg	Protospacer
****************

33. spacer 14.1|1851536|16|NC_008312|CRISPRCasFinder matches to position: 6468189-6468204, mismatch: 0, identity: 1.0

tctggtgttggttctg	CRISPR spacer
tctggtgttggttctg	Protospacer
****************

34. spacer 14.1|1851536|16|NC_008312|CRISPRCasFinder matches to position: 6468237-6468252, mismatch: 0, identity: 1.0

tctggtgttggttctg	CRISPR spacer
tctggtgttggttctg	Protospacer
****************

35. spacer 14.1|1851536|16|NC_008312|CRISPRCasFinder matches to position: 6468249-6468264, mismatch: 0, identity: 1.0

tctggtgttggttctg	CRISPR spacer
tctggtgttggttctg	Protospacer
****************

36. spacer 14.1|1851536|16|NC_008312|CRISPRCasFinder matches to position: 6468261-6468276, mismatch: 0, identity: 1.0

tctggtgttggttctg	CRISPR spacer
tctggtgttggttctg	Protospacer
****************

37. spacer 14.1|1851536|16|NC_008312|CRISPRCasFinder matches to position: 6468273-6468288, mismatch: 0, identity: 1.0

tctggtgttggttctg	CRISPR spacer
tctggtgttggttctg	Protospacer
****************

38. spacer 14.1|1851536|16|NC_008312|CRISPRCasFinder matches to position: 6468285-6468300, mismatch: 0, identity: 1.0

tctggtgttggttctg	CRISPR spacer
tctggtgttggttctg	Protospacer
****************

39. spacer 21.32|2628710|26|NC_008312|CRT matches to position: 2631433-2631458, mismatch: 0, identity: 1.0

tcaattttttgaggttttaggtgtta	CRISPR spacer
tcaattttttgaggttttaggtgtta	Protospacer
**************************

40. spacer 21.39|2629023|19|NC_008312|CRT matches to position: 2627131-2627149, mismatch: 0, identity: 1.0

tgaagttttaagtctcaat	CRISPR spacer
tgaagttttaagtctcaat	Protospacer
*******************

41. spacer 21.41|2629118|25|NC_008312|CRT matches to position: 2627125-2627149, mismatch: 0, identity: 1.0

taggtttgaagttttaagtctcaat	CRISPR spacer
taggtttgaagttttaagtctcaat	Protospacer
*************************

42. spacer 21.43|2629205|19|NC_008312|CRT matches to position: 2627131-2627149, mismatch: 0, identity: 1.0

tgaagttttaagtctcaat	CRISPR spacer
tgaagttttaagtctcaat	Protospacer
*******************

43. spacer 21.45|2629300|25|NC_008312|CRT matches to position: 2627125-2627149, mismatch: 0, identity: 1.0

taggtttgaagttttaagtctcaat	CRISPR spacer
taggtttgaagttttaagtctcaat	Protospacer
*************************

44. spacer 21.79|2631121|19|NC_008312|CRT matches to position: 2627131-2627149, mismatch: 0, identity: 1.0

tgaagttttaagtctcaat	CRISPR spacer
tgaagttttaagtctcaat	Protospacer
*******************

45. spacer 33.1|4206516|31|NC_008312|CRISPRCasFinder matches to position: 4208808-4208838, mismatch: 0, identity: 1.0

aagttgagctaataaataatctgctgatttt	CRISPR spacer
aagttgagctaataaataatctgctgatttt	Protospacer
*******************************

46. spacer 45.1|6864494|18|NC_008312|CRT matches to position: 6864878-6864895, mismatch: 0, identity: 1.0

taggcgtggcggttggcg	CRISPR spacer
taggcgtggcggttggcg	Protospacer
******************

47. spacer 3.5|613147|20|NC_008312|CRT matches to position: 616912-616931, mismatch: 1, identity: 0.95

gggcaccacttgggcctata	CRISPR spacer
gggcaccacttggacctata	Protospacer
*************.******

48. spacer 3.5|613147|20|NC_008312|CRT matches to position: 617497-617516, mismatch: 1, identity: 0.95

gggcaccacttgggcctata	CRISPR spacer
gggcaccacttggacctata	Protospacer
*************.******

49. spacer 3.12|613408|38|NC_008312|CRT matches to position: 617533-617570, mismatch: 1, identity: 0.974

taagaccaggaacaccatcagctccagcaggacctaca	CRISPR spacer
taagaccaggaacaccatcagctccagccggacctaca	Protospacer
**************************** *********

50. spacer 3.15|613633|38|NC_008312|CRT matches to position: 617767-617804, mismatch: 1, identity: 0.974

caagaccaggaataccatcagctccagccggacccaca	CRISPR spacer
caagaccaggaacaccatcagctccagccggacccaca	Protospacer
************.*************************

51. spacer 3.17|613777|47|NC_008312|CRT matches to position: 617092-617138, mismatch: 1, identity: 0.979

caagaccaggaacaccatcagctccagccggacctacaggacctatt	CRISPR spacer
caagaccaggaacaccatcagctccagctggacctacaggacctatt	Protospacer
****************************.******************

52. spacer 3.17|613777|47|NC_008312|CRT matches to position: 617767-617813, mismatch: 1, identity: 0.979

caagaccaggaacaccatcagctccagccggacctacaggacctatt	CRISPR spacer
caagaccaggaacaccatcagctccagccggacccacaggacctatt	Protospacer
**********************************.************

53. spacer 3.27|614371|38|NC_008312|CRT matches to position: 616849-616886, mismatch: 1, identity: 0.974

caagaccaggaacaccatcagctccagccggacccaca	CRISPR spacer
caaggccaggaacaccatcagctccagccggacccaca	Protospacer
****.*********************************

54. spacer 3.28|614434|20|NC_008312|CRT matches to position: 617146-617165, mismatch: 1, identity: 0.95

cgggaccaggggcaccactt	CRISPR spacer
cgggaccaggggctccactt	Protospacer
************* ******

55. spacer 3.38|614983|38|NC_008312|CRT matches to position: 616849-616886, mismatch: 1, identity: 0.974

caagaccaggaacaccatcagctccagccggacccaca	CRISPR spacer
caaggccaggaacaccatcagctccagccggacccaca	Protospacer
****.*********************************

56. spacer 3.39|615046|20|NC_008312|CRT matches to position: 617146-617165, mismatch: 1, identity: 0.95

cgggaccaggggcaccactt	CRISPR spacer
cgggaccaggggctccactt	Protospacer
************* ******

57. spacer 3.42|615217|38|NC_008312|CRT matches to position: 616849-616886, mismatch: 1, identity: 0.974

caagaccaggaacaccatcagctccagccggacccaca	CRISPR spacer
caaggccaggaacaccatcagctccagccggacccaca	Protospacer
****.*********************************

58. spacer 3.49|615631|38|NC_008312|CRT matches to position: 616948-616985, mismatch: 1, identity: 0.974

taagaccaggaacaccatcagctccagccggacctaca	CRISPR spacer
taagaccaggaacaccatcagctccagccggacccaca	Protospacer
**********************************.***

59. spacer 3.56|616237|38|NC_008312|CRT matches to position: 617542-617579, mismatch: 1, identity: 0.974

gaacaccatcagctccagctggacctacaggacctatt	CRISPR spacer
gaacaccatcagctccagccggacctacaggacctatt	Protospacer
*******************.******************

60. spacer 3.62|616750|47|NC_008312|CRT matches to position: 617056-617102, mismatch: 1, identity: 0.979

caggacctacaggacctataggacctacaggaccagcaagaccagga	CRISPR spacer
caggacctacaggacctacaggacctacaggaccagcaagaccagga	Protospacer
******************.****************************

61. spacer 3.63|616822|38|NC_008312|CRT matches to position: 617065-617102, mismatch: 1, identity: 0.974

caggacctacaggacctacaggaccagcaaggccagga	CRISPR spacer
caggacctacaggacctacaggaccagcaagaccagga	Protospacer
*******************************.******

62. spacer 4.2|617254|29|NC_008312|CRT matches to position: 617632-617660, mismatch: 1, identity: 0.966

caagaccagcgggaccaggagctccagtt	CRISPR spacer
caggaccagcgggaccaggagctccagtt	Protospacer
**.**************************

63. spacer 10.1|1399212|19|NC_008312|CRISPRCasFinder matches to position: 3181536-3181554, mismatch: 1, identity: 0.947

agaagttaaaagtcaaaag	CRISPR spacer
agaagtcaaaagtcaaaag	Protospacer
******.************

64. spacer 21.23|2628331|40|NC_008312|CRT matches to position: 2631433-2631472, mismatch: 1, identity: 0.975

tcaattttttgaggttttaggtgttaggtttgaggtttga	CRISPR spacer
tcaattttttgaggttttaggtgttaggtttgaagtttga	Protospacer
*********************************.******

65. spacer 21.27|2628512|19|NC_008312|CRT matches to position: 3958059-3958077, mismatch: 1, identity: 0.947

tcaattttttgaggtttga	CRISPR spacer
tcaatttgttgaggtttga	Protospacer
******* ***********

66. spacer 21.29|2628592|19|NC_008312|CRT matches to position: 3958059-3958077, mismatch: 1, identity: 0.947

tcaattttttgaggtttga	CRISPR spacer
tcaatttgttgaggtttga	Protospacer
******* ***********

67. spacer 23.1|2941370|38|NC_008312|CRT matches to position: 2941312-2941349, mismatch: 1, identity: 0.974

tttaggttttaggttttaggttttaggttttaagtttt	CRISPR spacer
tttaggttttaggtttgaggttttaggttttaagtttt	Protospacer
**************** *********************

68. spacer 23.1|2941370|38|NC_008312|CRT matches to position: 3331256-3331293, mismatch: 1, identity: 0.974

tttaggttttaggttttaggttttaggttttaagtttt	CRISPR spacer
tttaggttttaggttttaggttttaggttttaggtttt	Protospacer
********************************.*****

69. spacer 23.1|2941370|38|NC_008312|CRT matches to position: 3331510-3331547, mismatch: 1, identity: 0.974

tttaggttttaggttttaggttttaggttttaagtttt	CRISPR spacer
tttaggttttaggttttaggttttaggttttaggtttt	Protospacer
********************************.*****

70. spacer 33.1|4206516|31|NC_008312|CRISPRCasFinder matches to position: 4206720-4206750, mismatch: 1, identity: 0.968

aagttgagctaataaataatctgctgatttt	CRISPR spacer
aagttgagctaataaataatctgctggtttt	Protospacer
**************************.****

71. spacer 33.1|4206516|31|NC_008312|CRISPRCasFinder matches to position: 4206924-4206954, mismatch: 1, identity: 0.968

aagttgagctaataaataatctgctgatttt	CRISPR spacer
aagttgagctaataaataatctgctggtttt	Protospacer
**************************.****

72. spacer 33.1|4206516|31|NC_008312|CRISPRCasFinder matches to position: 4207128-4207158, mismatch: 1, identity: 0.968

aagttgagctaataaataatctgctgatttt	CRISPR spacer
aagttgagctaataaataatctgctggtttt	Protospacer
**************************.****

73. spacer 33.1|4206516|31|NC_008312|CRISPRCasFinder matches to position: 4207788-4207818, mismatch: 1, identity: 0.968

aagttgagctaataaataatctgctgatttt	CRISPR spacer
aagttgagctaataaataatctgctggtttt	Protospacer
**************************.****

74. spacer 33.1|4206516|31|NC_008312|CRISPRCasFinder matches to position: 4207992-4208022, mismatch: 1, identity: 0.968

aagttgagctaataaataatctgctgatttt	CRISPR spacer
aagttgagctaataaataatctgctggtttt	Protospacer
**************************.****

75. spacer 33.1|4206516|31|NC_008312|CRISPRCasFinder matches to position: 4208196-4208226, mismatch: 1, identity: 0.968

aagttgagctaataaataatctgctgatttt	CRISPR spacer
aagttgagctaataaataatctgctggtttt	Protospacer
**************************.****

76. spacer 33.1|4206516|31|NC_008312|CRISPRCasFinder matches to position: 4208604-4208634, mismatch: 1, identity: 0.968

aagttgagctaataaataatctgctgatttt	CRISPR spacer
aagttgagctaataaataatctgctggtttt	Protospacer
**************************.****

77. spacer 33.1|4206516|31|NC_008312|CRISPRCasFinder matches to position: 4209012-4209042, mismatch: 1, identity: 0.968

aagttgagctaataaataatctgctgatttt	CRISPR spacer
aagttgagctaataaataatctgctggtttt	Protospacer
**************************.****

78. spacer 3.2|613003|20|NC_008312|CRT matches to position: 616948-616967, mismatch: 2, identity: 0.9

taaaaccaggagcaccatca	CRISPR spacer
taagaccaggaacaccatca	Protospacer
***.*******.********

79. spacer 3.2|613003|20|NC_008312|CRT matches to position: 617533-617552, mismatch: 2, identity: 0.9

taaaaccaggagcaccatca	CRISPR spacer
taagaccaggaacaccatca	Protospacer
***.*******.********

80. spacer 3.4|613093|29|NC_008312|CRT matches to position: 616948-616976, mismatch: 2, identity: 0.931

taaaaccaggagcaccatcagctccagcc	CRISPR spacer
taagaccaggaacaccatcagctccagcc	Protospacer
***.*******.*****************

81. spacer 3.4|613093|29|NC_008312|CRT matches to position: 617533-617561, mismatch: 2, identity: 0.931

taaaaccaggagcaccatcagctccagcc	CRISPR spacer
taagaccaggaacaccatcagctccagcc	Protospacer
***.*******.*****************

82. spacer 3.5|613147|20|NC_008312|CRT matches to position: 617155-617174, mismatch: 2, identity: 0.9

gggcaccacttgggcctata	CRISPR spacer
gggctccacttggacctata	Protospacer
**** ********.******

83. spacer 3.5|613147|20|NC_008312|CRT matches to position: 617686-617705, mismatch: 2, identity: 0.9

gggcaccacttgggcctata	CRISPR spacer
gggcaccacttggaccaata	Protospacer
*************.** ***

84. spacer 3.5|613147|20|NC_008312|CRT matches to position: 617839-617858, mismatch: 2, identity: 0.9

gggcaccacttgggcctata	CRISPR spacer
gggcaccacttggaccgata	Protospacer
*************.** ***

85. spacer 3.12|613408|38|NC_008312|CRT matches to position: 616948-616985, mismatch: 2, identity: 0.947

taagaccaggaacaccatcagctccagcaggacctaca	CRISPR spacer
taagaccaggaacaccatcagctccagccggacccaca	Protospacer
**************************** *****.***

86. spacer 3.15|613633|38|NC_008312|CRT matches to position: 616849-616886, mismatch: 2, identity: 0.947

caagaccaggaataccatcagctccagccggacccaca	CRISPR spacer
caaggccaggaacaccatcagctccagccggacccaca	Protospacer
****.*******.*************************

87. spacer 3.17|613777|47|NC_008312|CRT matches to position: 616849-616895, mismatch: 2, identity: 0.957

caagaccaggaacaccatcagctccagccggacctacaggacctatt	CRISPR spacer
caaggccaggaacaccatcagctccagccggacccacaggacctatt	Protospacer
****.*****************************.************

88. spacer 3.26|614326|20|NC_008312|CRT matches to position: 617488-617507, mismatch: 2, identity: 0.9

caggaccaggagcaccagtt	CRISPR spacer
caggaccaggggcaccactt	Protospacer
**********.****** **

89. spacer 3.26|614326|20|NC_008312|CRT matches to position: 617677-617696, mismatch: 2, identity: 0.9

caggaccaggagcaccagtt	CRISPR spacer
caggaccaggggcaccactt	Protospacer
**********.****** **

90. spacer 3.26|614326|20|NC_008312|CRT matches to position: 617830-617849, mismatch: 2, identity: 0.9

caggaccaggagcaccagtt	CRISPR spacer
caggaccaggggcaccactt	Protospacer
**********.****** **

91. spacer 3.26|614326|20|NC_008312|CRT matches to position: 617866-617885, mismatch: 2, identity: 0.9

caggaccaggagcaccagtt	CRISPR spacer
caggaccaggggcaccactt	Protospacer
**********.****** **

92. spacer 3.27|614371|38|NC_008312|CRT matches to position: 617092-617129, mismatch: 2, identity: 0.947

caagaccaggaacaccatcagctccagccggacccaca	CRISPR spacer
caagaccaggaacaccatcagctccagctggacctaca	Protospacer
****************************.*****.***

93. spacer 3.27|614371|38|NC_008312|CRT matches to position: 617596-617633, mismatch: 2, identity: 0.947

caagaccaggaacaccatcagctccagccggacccaca	CRISPR spacer
caagaccaggaacaccatcagctccagctggacctaca	Protospacer
****************************.*****.***

94. spacer 3.37|614938|20|NC_008312|CRT matches to position: 617488-617507, mismatch: 2, identity: 0.9

caggaccaggagcaccagtt	CRISPR spacer
caggaccaggggcaccactt	Protospacer
**********.****** **

95. spacer 3.37|614938|20|NC_008312|CRT matches to position: 617677-617696, mismatch: 2, identity: 0.9

caggaccaggagcaccagtt	CRISPR spacer
caggaccaggggcaccactt	Protospacer
**********.****** **

96. spacer 3.37|614938|20|NC_008312|CRT matches to position: 617830-617849, mismatch: 2, identity: 0.9

caggaccaggagcaccagtt	CRISPR spacer
caggaccaggggcaccactt	Protospacer
**********.****** **

97. spacer 3.37|614938|20|NC_008312|CRT matches to position: 617866-617885, mismatch: 2, identity: 0.9

caggaccaggagcaccagtt	CRISPR spacer
caggaccaggggcaccactt	Protospacer
**********.****** **

98. spacer 3.38|614983|38|NC_008312|CRT matches to position: 617092-617129, mismatch: 2, identity: 0.947

caagaccaggaacaccatcagctccagccggacccaca	CRISPR spacer
caagaccaggaacaccatcagctccagctggacctaca	Protospacer
****************************.*****.***

99. spacer 3.38|614983|38|NC_008312|CRT matches to position: 617596-617633, mismatch: 2, identity: 0.947

caagaccaggaacaccatcagctccagccggacccaca	CRISPR spacer
caagaccaggaacaccatcagctccagctggacctaca	Protospacer
****************************.*****.***

100. spacer 3.42|615217|38|NC_008312|CRT matches to position: 617092-617129, mismatch: 2, identity: 0.947

caagaccaggaacaccatcagctccagccggacccaca	CRISPR spacer
caagaccaggaacaccatcagctccagctggacctaca	Protospacer
****************************.*****.***

101. spacer 3.42|615217|38|NC_008312|CRT matches to position: 617596-617633, mismatch: 2, identity: 0.947

caagaccaggaacaccatcagctccagccggacccaca	CRISPR spacer
caagaccaggaacaccatcagctccagctggacctaca	Protospacer
****************************.*****.***

102. spacer 3.47|615541|20|NC_008312|CRT matches to position: 617488-617507, mismatch: 2, identity: 0.9

caggaccaggagcaccagtt	CRISPR spacer
caggaccaggggcaccactt	Protospacer
**********.****** **

103. spacer 3.47|615541|20|NC_008312|CRT matches to position: 617677-617696, mismatch: 2, identity: 0.9

caggaccaggagcaccagtt	CRISPR spacer
caggaccaggggcaccactt	Protospacer
**********.****** **

104. spacer 3.47|615541|20|NC_008312|CRT matches to position: 617830-617849, mismatch: 2, identity: 0.9

caggaccaggagcaccagtt	CRISPR spacer
caggaccaggggcaccactt	Protospacer
**********.****** **

105. spacer 3.47|615541|20|NC_008312|CRT matches to position: 617866-617885, mismatch: 2, identity: 0.9

caggaccaggagcaccagtt	CRISPR spacer
caggaccaggggcaccactt	Protospacer
**********.****** **

106. spacer 3.56|616237|38|NC_008312|CRT matches to position: 616858-616895, mismatch: 2, identity: 0.947

gaacaccatcagctccagctggacctacaggacctatt	CRISPR spacer
gaacaccatcagctccagccggacccacaggacctatt	Protospacer
*******************.*****.************

107. spacer 3.56|616237|38|NC_008312|CRT matches to position: 616957-616994, mismatch: 2, identity: 0.947

gaacaccatcagctccagctggacctacaggacctatt	CRISPR spacer
gaacaccatcagctccagccggacccacaggacctatt	Protospacer
*******************.*****.************

108. spacer 3.56|616237|38|NC_008312|CRT matches to position: 617776-617813, mismatch: 2, identity: 0.947

gaacaccatcagctccagctggacctacaggacctatt	CRISPR spacer
gaacaccatcagctccagccggacccacaggacctatt	Protospacer
*******************.*****.************

109. spacer 4.4|617380|20|NC_008312|CRT matches to position: 617146-617165, mismatch: 2, identity: 0.9

cgggaccaggagctccagtt	CRISPR spacer
cgggaccaggggctccactt	Protospacer
**********.****** **

110. spacer 10.1|1399212|19|NC_008312|CRISPRCasFinder matches to position: 312968-312986, mismatch: 2, identity: 0.895

agaagttaaaagtcaaaag	CRISPR spacer
agaagttaaaagctaaaag	Protospacer
************..*****

111. spacer 10.1|1399212|19|NC_008312|CRISPRCasFinder matches to position: 2082368-2082386, mismatch: 2, identity: 0.895

agaagttaaaagtcaaaag	CRISPR spacer
agaagtcagaagtcaaaag	Protospacer
******.*.**********

112. spacer 10.1|1399212|19|NC_008312|CRISPRCasFinder matches to position: 2267182-2267200, mismatch: 2, identity: 0.895

agaagttaaaagtcaaaag	CRISPR spacer
agaagttaaaattcacaag	Protospacer
*********** *** ***

113. spacer 10.1|1399212|19|NC_008312|CRISPRCasFinder matches to position: 2825631-2825649, mismatch: 2, identity: 0.895

agaagttaaaagtcaaaag	CRISPR spacer
agaagttaaaagttagaag	Protospacer
*************.*.***

114. spacer 10.1|1399212|19|NC_008312|CRISPRCasFinder matches to position: 3001789-3001807, mismatch: 2, identity: 0.895

agaagttaaaagtcaaaag	CRISPR spacer
agaagttaaaagttagaag	Protospacer
*************.*.***

115. spacer 10.1|1399212|19|NC_008312|CRISPRCasFinder matches to position: 4961158-4961176, mismatch: 2, identity: 0.895

agaagttaaaagtcaaaag	CRISPR spacer
agaatttaaaagttaaaag	Protospacer
**** ********.*****

116. spacer 10.1|1399212|19|NC_008312|CRISPRCasFinder matches to position: 6605857-6605875, mismatch: 2, identity: 0.895

agaagttaaaagtcaaaag	CRISPR spacer
agaaggtaaaagtcaagag	Protospacer
***** **********.**

117. spacer 10.1|1399212|19|NC_008312|CRISPRCasFinder matches to position: 7534704-7534722, mismatch: 2, identity: 0.895

agaagttaaaagtcaaaag	CRISPR spacer
agaagtcaaaactcaaaag	Protospacer
******.**** *******

118. spacer 17.1|1941253|35|NC_008312|CRISPRCasFinder matches to position: 7654959-7654993, mismatch: 2, identity: 0.943

taatagttaaagcaagaaattataaagatttaatt	CRISPR spacer
taaaagttaaagcaagaaattataaagattgaatt	Protospacer
*** ************************** ****

119. spacer 21.1|2627152|26|NC_008312|CRT matches to position: 2631447-2631472, mismatch: 2, identity: 0.923

tttgaggttttaggtttgaagtttga	CRISPR spacer
ttttaggtgttaggtttgaagtttga	Protospacer
*** **** *****************

120. spacer 21.1|2627152|26|NC_008312|CRT matches to position: 2941890-2941915, mismatch: 2, identity: 0.923

tttgaggttttaggtttgaagtttga	CRISPR spacer
tttgaggttttaggttttaggtttga	Protospacer
***************** *.******

121. spacer 21.6|2627443|25|NC_008312|CRT matches to position: 848634-848658, mismatch: 2, identity: 0.92

tttgaggttttaggttttaggtgtt	CRISPR spacer
tttcaggttttaggttttaggtttt	Protospacer
*** ****************** **

122. spacer 21.6|2627443|25|NC_008312|CRT matches to position: 1538289-1538313, mismatch: 2, identity: 0.92

tttgaggttttaggttttaggtgtt	CRISPR spacer
ttttaggttttgggttttaggtgtt	Protospacer
*** *******.*************

123. spacer 21.6|2627443|25|NC_008312|CRT matches to position: 1538848-1538872, mismatch: 2, identity: 0.92

tttgaggttttaggttttaggtgtt	CRISPR spacer
tttgaggtgttaggtttgaggtgtt	Protospacer
******** ******** *******

124. spacer 21.6|2627443|25|NC_008312|CRT matches to position: 2705216-2705240, mismatch: 2, identity: 0.92

tttgaggttttaggttttaggtgtt	CRISPR spacer
ttttaggttttaggttttaggtttt	Protospacer
*** ****************** **

125. spacer 21.6|2627443|25|NC_008312|CRT matches to position: 2705223-2705247, mismatch: 2, identity: 0.92

tttgaggttttaggttttaggtgtt	CRISPR spacer
ttttaggttttaggttttaggtttt	Protospacer
*** ****************** **

126. spacer 21.6|2627443|25|NC_008312|CRT matches to position: 2941325-2941349, mismatch: 2, identity: 0.92

tttgaggttttaggttttaggtgtt	CRISPR spacer
tttgaggttttaggttttaagtttt	Protospacer
*******************.** **

127. spacer 21.6|2627443|25|NC_008312|CRT matches to position: 2941883-2941907, mismatch: 2, identity: 0.92

tttgaggttttaggttttaggtgtt	CRISPR spacer
tttgaggtttgaggttttaggtttt	Protospacer
********** *********** **

128. spacer 21.6|2627443|25|NC_008312|CRT matches to position: 3331256-3331280, mismatch: 2, identity: 0.92

tttgaggttttaggttttaggtgtt	CRISPR spacer
ttttaggttttaggttttaggtttt	Protospacer
*** ****************** **

129. spacer 21.6|2627443|25|NC_008312|CRT matches to position: 3331263-3331287, mismatch: 2, identity: 0.92

tttgaggttttaggttttaggtgtt	CRISPR spacer
ttttaggttttaggttttaggtttt	Protospacer
*** ****************** **

130. spacer 21.6|2627443|25|NC_008312|CRT matches to position: 3331510-3331534, mismatch: 2, identity: 0.92

tttgaggttttaggttttaggtgtt	CRISPR spacer
ttttaggttttaggttttaggtttt	Protospacer
*** ****************** **

131. spacer 21.6|2627443|25|NC_008312|CRT matches to position: 3331517-3331541, mismatch: 2, identity: 0.92

tttgaggttttaggttttaggtgtt	CRISPR spacer
ttttaggttttaggttttaggtttt	Protospacer
*** ****************** **

132. spacer 21.6|2627443|25|NC_008312|CRT matches to position: 3331806-3331830, mismatch: 2, identity: 0.92

tttgaggttttaggttttaggtgtt	CRISPR spacer
ttttaggctttaggttttaggtgtt	Protospacer
*** ***.*****************

133. spacer 21.6|2627443|25|NC_008312|CRT matches to position: 3375636-3375660, mismatch: 2, identity: 0.92

tttgaggttttaggttttaggtgtt	CRISPR spacer
ttttaggttttaggtttcaggtgtt	Protospacer
*** *************.*******

134. spacer 21.6|2627443|25|NC_008312|CRT matches to position: 4271750-4271774, mismatch: 2, identity: 0.92

tttgaggttttaggttttaggtgtt	CRISPR spacer
tttgaagttttaggttttaggtttt	Protospacer
*****.**************** **

135. spacer 21.6|2627443|25|NC_008312|CRT matches to position: 5423269-5423293, mismatch: 2, identity: 0.92

tttgaggttttaggttttaggtgtt	CRISPR spacer
ttttaggttttaggttttaggtttt	Protospacer
*** ****************** **

136. spacer 21.6|2627443|25|NC_008312|CRT matches to position: 7558976-7559000, mismatch: 2, identity: 0.92

tttgaggttttaggttttaggtgtt	CRISPR spacer
ttttaggttttaggttttaggtttt	Protospacer
*** ****************** **

137. spacer 21.9|2627587|19|NC_008312|CRT matches to position: 2941869-2941887, mismatch: 2, identity: 0.895

tgaggtctcaattttttga	CRISPR spacer
tgaggtgttaattttttga	Protospacer
****** *.**********

138. spacer 21.9|2627587|19|NC_008312|CRT matches to position: 7158754-7158772, mismatch: 2, identity: 0.895

tgaggtctcaattttttga	CRISPR spacer
tggggtatcaattttttga	Protospacer
**.*** ************

139. spacer 21.10|2627624|26|NC_008312|CRT matches to position: 2941341-2941366, mismatch: 2, identity: 0.923

ttaagtttgaggtctcaattttttga	CRISPR spacer
ttaagttttaggtgtcaattttttga	Protospacer
******** **** ************

140. spacer 21.20|2628213|19|NC_008312|CRT matches to position: 1922549-1922567, mismatch: 2, identity: 0.895

tcaattttttgaggtttta	CRISPR spacer
tcattttttagaggtttta	Protospacer
*** ***** *********

141. spacer 21.20|2628213|19|NC_008312|CRT matches to position: 4987966-4987984, mismatch: 2, identity: 0.895

tcaattttttgaggtttta	CRISPR spacer
tcaattttttgatgattta	Protospacer
************ * ****

142. spacer 21.20|2628213|19|NC_008312|CRT matches to position: 5832720-5832738, mismatch: 2, identity: 0.895

tcaattttttgaggtttta	CRISPR spacer
tctattttttgagttttta	Protospacer
** ********** *****

143. spacer 21.20|2628213|19|NC_008312|CRT matches to position: 7325462-7325480, mismatch: 2, identity: 0.895

tcaattttttgaggtttta	CRISPR spacer
tcaatttgttgaggattta	Protospacer
******* ****** ****

144. spacer 21.22|2628294|19|NC_008312|CRT matches to position: 4987966-4987984, mismatch: 2, identity: 0.895

tcaattttttgaggcttta	CRISPR spacer
tcaattttttgatgattta	Protospacer
************ * ****

145. spacer 21.22|2628294|19|NC_008312|CRT matches to position: 7325462-7325480, mismatch: 2, identity: 0.895

tcaattttttgaggcttta	CRISPR spacer
tcaatttgttgaggattta	Protospacer
******* ****** ****

146. spacer 21.26|2628475|19|NC_008312|CRT matches to position: 1922549-1922567, mismatch: 2, identity: 0.895

tcaattttttgaggtttta	CRISPR spacer
tcattttttagaggtttta	Protospacer
*** ***** *********

147. spacer 21.26|2628475|19|NC_008312|CRT matches to position: 4987966-4987984, mismatch: 2, identity: 0.895

tcaattttttgaggtttta	CRISPR spacer
tcaattttttgatgattta	Protospacer
************ * ****

148. spacer 21.26|2628475|19|NC_008312|CRT matches to position: 5832720-5832738, mismatch: 2, identity: 0.895

tcaattttttgaggtttta	CRISPR spacer
tctattttttgagttttta	Protospacer
** ********** *****

149. spacer 21.26|2628475|19|NC_008312|CRT matches to position: 7325462-7325480, mismatch: 2, identity: 0.895

tcaattttttgaggtttta	CRISPR spacer
tcaatttgttgaggattta	Protospacer
******* ****** ****

150. spacer 21.30|2628629|19|NC_008312|CRT matches to position: 1282036-1282054, mismatch: 2, identity: 0.895

tgaggtctcatttttttga	CRISPR spacer
tgagggctaatttttttga	Protospacer
***** ** **********

151. spacer 21.30|2628629|19|NC_008312|CRT matches to position: 1993335-1993353, mismatch: 2, identity: 0.895

tgaggtctcatttttttga	CRISPR spacer
tgagatttcatttttttga	Protospacer
****.*.************

152. spacer 21.33|2628754|19|NC_008312|CRT matches to position: 2698721-2698739, mismatch: 2, identity: 0.895

tgaagtttgaggtctcatt	CRISPR spacer
tgaagtttgaggtcacgtt	Protospacer
************** *.**

153. spacer 21.39|2629023|19|NC_008312|CRT matches to position: 2396366-2396384, mismatch: 2, identity: 0.895

tgaagttttaagtctcaat	CRISPR spacer
tgaagttgtaagactcaat	Protospacer
******* **** ******

154. spacer 21.43|2629205|19|NC_008312|CRT matches to position: 2396366-2396384, mismatch: 2, identity: 0.895

tgaagttttaagtctcaat	CRISPR spacer
tgaagttgtaagactcaat	Protospacer
******* **** ******

155. spacer 21.56|2630042|25|NC_008312|CRT matches to position: 2627125-2627149, mismatch: 2, identity: 0.92

taggtttgaagtttgaggtctcaat	CRISPR spacer
taggtttgaagttttaagtctcaat	Protospacer
************** *.********

156. spacer 21.64|2630418|19|NC_008312|CRT matches to position: 2698721-2698739, mismatch: 2, identity: 0.895

tgaagtttgaggtctcatt	CRISPR spacer
tgaagtttgaggtcacgtt	Protospacer
************** *.**

157. spacer 21.71|2630759|19|NC_008312|CRT matches to position: 2698721-2698739, mismatch: 2, identity: 0.895

tgaagtttgaggtctcatt	CRISPR spacer
tgaagtttgaggtcacgtt	Protospacer
************** *.**

158. spacer 21.76|2630998|19|NC_008312|CRT matches to position: 2698721-2698739, mismatch: 2, identity: 0.895

tgaagtttgaggtctcatt	CRISPR spacer
tgaagtttgaggtcacgtt	Protospacer
************** *.**

159. spacer 21.77|2631035|25|NC_008312|CRT matches to position: 2941335-2941359, mismatch: 2, identity: 0.92

taggttttaagtttgaggtatcaat	CRISPR spacer
taggttttaagttttaggtgtcaat	Protospacer
************** ****.*****

160. spacer 21.78|2631078|25|NC_008312|CRT matches to position: 2627125-2627149, mismatch: 2, identity: 0.92

taggtttgaagtttgaggtctcaat	CRISPR spacer
taggtttgaagttttaagtctcaat	Protospacer
************** *.********

161. spacer 21.79|2631121|19|NC_008312|CRT matches to position: 2396366-2396384, mismatch: 2, identity: 0.895

tgaagttttaagtctcaat	CRISPR spacer
tgaagttgtaagactcaat	Protospacer
******* **** ******

162. spacer 21.83|2631303|19|NC_008312|CRT matches to position: 2941341-2941359, mismatch: 2, identity: 0.895

ttaagtttgaggtctcaat	CRISPR spacer
ttaagttttaggtgtcaat	Protospacer
******** **** *****

163. spacer 21.83|2631303|19|NC_008312|CRT matches to position: 5816713-5816731, mismatch: 2, identity: 0.895

ttaagtttgaggtctcaat	CRISPR spacer
tttagtttgatgtctcaat	Protospacer
** ******* ********

164. spacer 23.1|2941370|38|NC_008312|CRT matches to position: 2705217-2705254, mismatch: 2, identity: 0.947

tttaggttttaggttttaggttttaggttttaagtttt	CRISPR spacer
tttaggttttaggttttaggttttaggttttagttttt	Protospacer
********************************. ****

165. spacer 23.1|2941370|38|NC_008312|CRT matches to position: 3331228-3331265, mismatch: 2, identity: 0.947

tttaggttttaggttttaggttttaggttttaagtttt	CRISPR spacer
tttaggttttaggctttaggttttaggttttaggtttt	Protospacer
*************.******************.*****

166. spacer 23.1|2941370|38|NC_008312|CRT matches to position: 3331235-3331272, mismatch: 2, identity: 0.947

tttaggttttaggttttaggttttaggttttaagtttt	CRISPR spacer
tttaggttttaggttttaggctttaggttttaggtttt	Protospacer
********************.***********.*****

167. spacer 23.1|2941370|38|NC_008312|CRT matches to position: 3331242-3331279, mismatch: 2, identity: 0.947

tttaggttttaggttttaggttttaggttttaagtttt	CRISPR spacer
tttaggttttaggttttaggttttaggctttaggtttt	Protospacer
***************************.****.*****

168. spacer 23.1|2941370|38|NC_008312|CRT matches to position: 3331249-3331286, mismatch: 2, identity: 0.947

tttaggttttaggttttaggttttaggttttaagtttt	CRISPR spacer
tttaggttttaggttttaggttttaggttttaggcttt	Protospacer
********************************.*.***

169. spacer 23.1|2941370|38|NC_008312|CRT matches to position: 3331263-3331300, mismatch: 2, identity: 0.947

tttaggttttaggttttaggttttaggttttaagtttt	CRISPR spacer
tttaggctttaggttttaggttttaggttttaggtttt	Protospacer
******.*************************.*****

170. spacer 23.1|2941370|38|NC_008312|CRT matches to position: 3331270-3331307, mismatch: 2, identity: 0.947

tttaggttttaggttttaggttttaggttttaagtttt	CRISPR spacer
tttaggttttaggctttaggttttaggttttaggtttt	Protospacer
*************.******************.*****

171. spacer 23.1|2941370|38|NC_008312|CRT matches to position: 3331277-3331314, mismatch: 2, identity: 0.947

tttaggttttaggttttaggttttaggttttaagtttt	CRISPR spacer
tttaggttttaggttttaggctttaggttttaggtttt	Protospacer
********************.***********.*****

172. spacer 23.1|2941370|38|NC_008312|CRT matches to position: 3331369-3331406, mismatch: 2, identity: 0.947

tttaggttttaggttttaggttttaggttttaagtttt	CRISPR spacer
tttaggttttaggttttaggttttaggctttaggtttt	Protospacer
***************************.****.*****

173. spacer 23.1|2941370|38|NC_008312|CRT matches to position: 3331383-3331420, mismatch: 2, identity: 0.947

tttaggttttaggttttaggttttaggttttaagtttt	CRISPR spacer
tttaggttttaggctttaggttttaggttttaggtttt	Protospacer
*************.******************.*****

174. spacer 23.1|2941370|38|NC_008312|CRT matches to position: 3331390-3331427, mismatch: 2, identity: 0.947

tttaggttttaggttttaggttttaggttttaagtttt	CRISPR spacer
tttaggttttaggttttaggctttaggttttaggtttt	Protospacer
********************.***********.*****

175. spacer 23.1|2941370|38|NC_008312|CRT matches to position: 3331496-3331533, mismatch: 2, identity: 0.947

tttaggttttaggttttaggttttaggttttaagtttt	CRISPR spacer
tttaggttttaggttttaggttttaggctttaggtttt	Protospacer
***************************.****.*****

176. spacer 23.1|2941370|38|NC_008312|CRT matches to position: 3331503-3331540, mismatch: 2, identity: 0.947

tttaggttttaggttttaggttttaggttttaagtttt	CRISPR spacer
tttaggttttaggttttaggttttaggttttaggcttt	Protospacer
********************************.*.***

177. spacer 23.1|2941370|38|NC_008312|CRT matches to position: 3331665-3331702, mismatch: 2, identity: 0.947

tttaggttttaggttttaggttttaggttttaagtttt	CRISPR spacer
tttaggttttaggttttaggctttaggttttaggtttt	Protospacer
********************.***********.*****

178. spacer 23.1|2941370|38|NC_008312|CRT matches to position: 3331686-3331723, mismatch: 2, identity: 0.947

tttaggttttaggttttaggttttaggttttaagtttt	CRISPR spacer
tttaggttttaggttttaggctttaggttttaggtttt	Protospacer
********************.***********.*****

179. spacer 29.1|3671521|26|NC_008312|CRISPRCasFinder matches to position: 3671479-3671504, mismatch: 2, identity: 0.923

aagcgaatattgatagtgctcaagct	CRISPR spacer
aagctaatattaatagtgctcaagct	Protospacer
**** ******.**************

180. spacer 3.43|615280|65|NC_008312|CRT matches to position: 616912-616976, mismatch: 5, identity: 0.923

gggcaccacttggacctataggaccaatgggaccagtaagaccaggaacaccatcagctc	CRISPR spacer
gggcaccacttggacctataggaccaatgggaccagtaagaccaggaacaccatcagctc	Protospacer
************************************************************

181. spacer 3.43|615280|65|NC_008312|CRT matches to position: 617497-617561, mismatch: 5, identity: 0.923

gggcaccacttggacctataggaccaatgggaccagtaagaccaggaacaccatcagctc	CRISPR spacer
gggcaccacttggacctataggaccaatgggaccagtaagaccaggaacaccatcagctc	Protospacer
************************************************************

182. spacer 3.43|615280|65|NC_008312|CRT matches to position: 617155-617219, mismatch: 6, identity: 0.908

gggcaccacttggacctataggaccaatgggaccagtaagaccaggaacaccatcagctc	CRISPR spacer
gggctccacttggacctataggaccaatgggaccagtaagaccaggaacaccatcagctc	Protospacer
**** *******************************************************

183. spacer 3.51|615775|74|NC_008312|CRT matches to position: 616912-616985, mismatch: 15, identity: 0.797

gggcaccacttggacctataggaccaatgggaccagtaagaccaggaacaccatcagatc	CRISPR spacer
gggcaccacttggacctataggaccaatgggaccagtaagaccaggaacaccatcagctc	Protospacer
********************************************************* **

184. spacer 3.51|615775|74|NC_008312|CRT matches to position: 617497-617570, mismatch: 15, identity: 0.797

gggcaccacttggacctataggaccaatgggaccagtaagaccaggaacaccatcagatc	CRISPR spacer
gggcaccacttggacctataggaccaatgggaccagtaagaccaggaacaccatcagctc	Protospacer
********************************************************* **

185. spacer 3.58|616381|74|NC_008312|CRT matches to position: 616912-616985, mismatch: 15, identity: 0.797

gggcaccacttggacctataggaccaataggaccagtaagaccaggaacaccatcagctc	CRISPR spacer
gggcaccacttggacctataggaccaatgggaccagtaagaccaggaacaccatcagctc	Protospacer
****************************.*******************************

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NC_008312_10	10.1|1399212|19|NC_008312|CRISPRCasFinder	1399212-1399230	19	NC_019772	Anabaena cylindrica PCC 7122 plasmid pANACY.01, complete sequence	155277-155295	0	1.0
NC_008312_10	10.1|1399212|19|NC_008312|CRISPRCasFinder	1399212-1399230	19	NC_019772	Anabaena cylindrica PCC 7122 plasmid pANACY.01, complete sequence	155322-155340	0	1.0
NC_008312_3	3.3|613048|20|NC_008312|CRT	613048-613067	20	MH153812	Rhodococcus phage Grayson, complete genome	46366-46385	1	0.95
NC_008312_23	23.1|2941370|38|NC_008312|CRT	2941370-2941407	38	NZ_CP015730	Bacillus cereus strain A1 plasmid pBCA1, complete sequence	77628-77665	1	0.974
NC_008312_23	23.1|2941370|38|NC_008312|CRT	2941370-2941407	38	NC_015511	Haliscomenobacter hydrossis DSM 1100 plasmid pHALHY01, complete sequence	2187-2224	1	0.974
NC_008312_21	21.3|2627277|25|NC_008312|CRT	2627277-2627301	25	NC_013547	Helicobacter pylori plasmid pAL226, complete sequence	9706-9730	2	0.92
NC_008312_21	21.6|2627443|25|NC_008312|CRT	2627443-2627467	25	NZ_CP015730	Bacillus cereus strain A1 plasmid pBCA1, complete sequence	77627-77651	2	0.92
NC_008312_21	21.6|2627443|25|NC_008312|CRT	2627443-2627467	25	NZ_CP015730	Bacillus cereus strain A1 plasmid pBCA1, complete sequence	77634-77658	2	0.92
NC_008312_21	21.6|2627443|25|NC_008312|CRT	2627443-2627467	25	NZ_CP015730	Bacillus cereus strain A1 plasmid pBCA1, complete sequence	77641-77665	2	0.92
NC_008312_21	21.6|2627443|25|NC_008312|CRT	2627443-2627467	25	NC_015511	Haliscomenobacter hydrossis DSM 1100 plasmid pHALHY01, complete sequence	2193-2217	2	0.92
NC_008312_23	23.1|2941370|38|NC_008312|CRT	2941370-2941407	38	NZ_CP015730	Bacillus cereus strain A1 plasmid pBCA1, complete sequence	77635-77672	2	0.947
NC_008312_21	21.1|2627152|26|NC_008312|CRT	2627152-2627177	26	NC_015511	Haliscomenobacter hydrossis DSM 1100 plasmid pHALHY01, complete sequence	2200-2225	3	0.885
NC_008312_21	21.3|2627277|25|NC_008312|CRT	2627277-2627301	25	NZ_CP038909	Piscirickettsia salmonis strain Psal-009 plasmid unnamed1, complete sequence	57269-57293	3	0.88
NC_008312_21	21.6|2627443|25|NC_008312|CRT	2627443-2627467	25	NZ_CP015730	Bacillus cereus strain A1 plasmid pBCA1, complete sequence	77648-77672	3	0.88
NC_008312_21	21.6|2627443|25|NC_008312|CRT	2627443-2627467	25	MG592416	Vibrio phage 1.032.O._10N.261.54.F5, partial genome	9537-9561	3	0.88
NC_008312_21	21.25|2628432|25|NC_008312|CRT	2628432-2628456	25	NC_017377	Helicobacter pylori Puno120 plasmid pHPPN120, complete sequence	5693-5717	3	0.88
NC_008312_21	21.25|2628432|25|NC_008312|CRT	2628432-2628456	25	NC_013547	Helicobacter pylori plasmid pAL226, complete sequence	9713-9737	3	0.88
NC_008312_23	23.1|2941370|38|NC_008312|CRT	2941370-2941407	38	NC_015511	Haliscomenobacter hydrossis DSM 1100 plasmid pHALHY01, complete sequence	2194-2231	3	0.921
NC_008312_3	3.24|614218|29|NC_008312|CRT	614218-614246	29	NC_017957	Tistrella mobilis KA081020-065 plasmid pTM1, complete sequence	235822-235850	4	0.862
NC_008312_3	3.33|614713|29|NC_008312|CRT	614713-614741	29	NC_017957	Tistrella mobilis KA081020-065 plasmid pTM1, complete sequence	235822-235850	4	0.862
NC_008312_12	12.14|1607246|27|NC_008312|CRT	1607246-1607272	27	MN831413	Enterococcus faecium strain M17/0314 plasmid pM17/0314, complete sequence	82186-82212	4	0.852
NC_008312_12	12.14|1607246|27|NC_008312|CRT	1607246-1607272	27	NZ_LT598665	Enterococcus faecium isolate Ef_aus00233 plasmid 3	62512-62538	4	0.852
NC_008312_21	21.6|2627443|25|NC_008312|CRT	2627443-2627467	25	NC_012696	Roseophage EE36P1, complete genome	2158-2182	4	0.84
NC_008312_21	21.14|2627879|25|NC_008312|CRT	2627879-2627903	25	NZ_CP021331	Maritalea myrionectae strain HL2708#5 plasmid pHL2708X3, complete sequence	25274-25298	4	0.84
NC_008312_21	21.14|2627879|25|NC_008312|CRT	2627879-2627903	25	KT337344	Streptococcus phage phiARI0274b, partial genome	4678-4702	4	0.84
NC_008312_21	21.14|2627879|25|NC_008312|CRT	2627879-2627903	25	NC_024361	Streptococcus phage DCC1738, complete sequence	8330-8354	4	0.84
NC_008312_21	21.14|2627879|25|NC_008312|CRT	2627879-2627903	25	KT337359	Streptococcus phage phiARI0468b-3, partial genome	1848-1872	4	0.84
NC_008312_21	21.14|2627879|25|NC_008312|CRT	2627879-2627903	25	KT337354	Streptococcus phage phiARI0462, complete genome	9364-9388	4	0.84
NC_008312_21	21.14|2627879|25|NC_008312|CRT	2627879-2627903	25	FR671410	Streptococcus phage 8140	5354-5378	4	0.84
NC_008312_21	21.14|2627879|25|NC_008312|CRT	2627879-2627903	25	KT337345	Streptococcus phage phiARI0285-1, partial genome	2583-2607	4	0.84
NC_008312_21	21.14|2627879|25|NC_008312|CRT	2627879-2627903	25	NC_031907	Streptococcus phage phiARI0746, complete genome	2362-2386	4	0.84
NC_008312_21	21.14|2627879|25|NC_008312|CRT	2627879-2627903	25	NC_024370	Streptococcus phage IC1, complete sequence	9557-9581	4	0.84
NC_008312_21	21.14|2627879|25|NC_008312|CRT	2627879-2627903	25	FR671405	Streptococcus phage V22	6260-6284	4	0.84
NC_008312_21	21.14|2627879|25|NC_008312|CRT	2627879-2627903	25	KT337352	Streptococcus phage phiARI0460-1, complete genome	8931-8955	4	0.84
NC_008312_21	21.14|2627879|25|NC_008312|CRT	2627879-2627903	25	KT337351	Streptococcus phage phiARI0455b, partial genome	1511-1535	4	0.84
NC_008312_21	21.14|2627879|25|NC_008312|CRT	2627879-2627903	25	FR671411	Streptococcus phage 2167	6232-6256	4	0.84
NC_008312_21	21.14|2627879|25|NC_008312|CRT	2627879-2627903	25	KT337369	Streptococcus phage phiARI0831b, partial genome	1523-1547	4	0.84
NC_008312_21	21.14|2627879|25|NC_008312|CRT	2627879-2627903	25	KT337362	Streptococcus phage phiARI0598b, partial genome	3961-3985	4	0.84
NC_008312_21	21.14|2627879|25|NC_008312|CRT	2627879-2627903	25	KT337340	Streptococcus phage phiARI0031, complete genome	10905-10929	4	0.84
NC_008312_21	21.14|2627879|25|NC_008312|CRT	2627879-2627903	25	KY065496	Streptococcus phage IPP60, complete genome	32238-32262	4	0.84
NC_008312_21	21.14|2627879|25|NC_008312|CRT	2627879-2627903	25	KY065505	Streptococcus phage IPP69, complete genome	31121-31145	4	0.84
NC_008312_21	21.14|2627879|25|NC_008312|CRT	2627879-2627903	25	KY065480	Streptococcus phage IPP40, complete genome	32372-32396	4	0.84
NC_008312_21	21.14|2627879|25|NC_008312|CRT	2627879-2627903	25	KY065478	Streptococcus phage IPP38, complete genome	32373-32397	4	0.84
NC_008312_21	21.14|2627879|25|NC_008312|CRT	2627879-2627903	25	KY065486	Streptococcus phage IPP46, complete genome	30540-30564	4	0.84
NC_008312_21	21.14|2627879|25|NC_008312|CRT	2627879-2627903	25	KY065500	Streptococcus phage IPP64, complete genome	30903-30927	4	0.84
NC_008312_21	21.14|2627879|25|NC_008312|CRT	2627879-2627903	25	KY065452	Streptococcus phage IPP10, complete genome	30909-30933	4	0.84
NC_008312_21	21.19|2628169|26|NC_008312|CRT	2628169-2628194	26	NZ_CP019854	Borreliella burgdorferi plasmid lp54, complete sequence	49055-49080	4	0.846
NC_008312_21	21.19|2628169|26|NC_008312|CRT	2628169-2628194	26	NZ_CP019765	Borreliella burgdorferi strain B31_NRZ isolate B31 plasmid p_lp54, complete sequence	49055-49080	4	0.846
NC_008312_21	21.19|2628169|26|NC_008312|CRT	2628169-2628194	26	NC_011784	Borreliella burgdorferi ZS7 plasmid ZS7_lp54, complete sequence	49040-49065	4	0.846
NC_008312_21	21.19|2628169|26|NC_008312|CRT	2628169-2628194	26	NC_001857	Borreliella burgdorferi B31 plasmid lp54, complete sequence	49062-49087	4	0.846
NC_008312_21	21.21|2628250|26|NC_008312|CRT	2628250-2628275	26	NZ_CP019854	Borreliella burgdorferi plasmid lp54, complete sequence	49055-49080	4	0.846
NC_008312_21	21.21|2628250|26|NC_008312|CRT	2628250-2628275	26	NZ_CP019765	Borreliella burgdorferi strain B31_NRZ isolate B31 plasmid p_lp54, complete sequence	49055-49080	4	0.846
NC_008312_21	21.21|2628250|26|NC_008312|CRT	2628250-2628275	26	NC_011784	Borreliella burgdorferi ZS7 plasmid ZS7_lp54, complete sequence	49040-49065	4	0.846
NC_008312_21	21.21|2628250|26|NC_008312|CRT	2628250-2628275	26	NC_001857	Borreliella burgdorferi B31 plasmid lp54, complete sequence	49062-49087	4	0.846
NC_008312_21	21.24|2628389|25|NC_008312|CRT	2628389-2628413	25	NC_017364	Helicobacter pylori Gambia94/24 plasmid, complete sequence	2033-2057	4	0.84
NC_008312_21	21.24|2628389|25|NC_008312|CRT	2628389-2628413	25	NC_017377	Helicobacter pylori Puno120 plasmid pHPPN120, complete sequence	5693-5717	4	0.84
NC_008312_21	21.24|2628389|25|NC_008312|CRT	2628389-2628413	25	NC_013547	Helicobacter pylori plasmid pAL226, complete sequence	9713-9737	4	0.84
NC_008312_21	21.24|2628389|25|NC_008312|CRT	2628389-2628413	25	AP018320	Nostoc sp. HK-01 plasmid plasmid2 DNA, complete genome	223896-223920	4	0.84
NC_008312_21	21.24|2628389|25|NC_008312|CRT	2628389-2628413	25	KF751797	Campylobacter phage CJIE4-5, complete genome	20821-20845	4	0.84
NC_008312_21	21.24|2628389|25|NC_008312|CRT	2628389-2628413	25	KF751794	Campylobacter phage CJIE4-2, complete genome	20574-20598	4	0.84
NC_008312_21	21.24|2628389|25|NC_008312|CRT	2628389-2628413	25	KF751795	Campylobacter phage CJIE4-3, complete genome	18827-18851	4	0.84
NC_008312_21	21.24|2628389|25|NC_008312|CRT	2628389-2628413	25	KF751796	Campylobacter phage CJIE4-4, complete genome	18865-18889	4	0.84
NC_008312_21	21.24|2628389|25|NC_008312|CRT	2628389-2628413	25	KF751793	Campylobacter phage CJIE4-1, complete genome	21768-21792	4	0.84
NC_008312_21	21.24|2628389|25|NC_008312|CRT	2628389-2628413	25	NZ_CP019854	Borreliella burgdorferi plasmid lp54, complete sequence	49055-49079	4	0.84
NC_008312_21	21.24|2628389|25|NC_008312|CRT	2628389-2628413	25	NZ_CP019765	Borreliella burgdorferi strain B31_NRZ isolate B31 plasmid p_lp54, complete sequence	49055-49079	4	0.84
NC_008312_21	21.24|2628389|25|NC_008312|CRT	2628389-2628413	25	NC_011784	Borreliella burgdorferi ZS7 plasmid ZS7_lp54, complete sequence	49040-49064	4	0.84
NC_008312_21	21.24|2628389|25|NC_008312|CRT	2628389-2628413	25	NC_001857	Borreliella burgdorferi B31 plasmid lp54, complete sequence	49062-49086	4	0.84
NC_008312_21	21.25|2628432|25|NC_008312|CRT	2628432-2628456	25	NZ_KM583814	Helicobacter pylori strain UM134 plasmid pUM134, complete sequence	8774-8798	4	0.84
NC_008312_21	21.25|2628432|25|NC_008312|CRT	2628432-2628456	25	NZ_CP018745	Borreliella garinii strain CIP 103362 isolate 20047 plasmid p_lp54_linear	43159-43183	4	0.84
NC_008312_21	21.25|2628432|25|NC_008312|CRT	2628432-2628456	25	NZ_CP028862	Borreliella garinii strain 20047 plasmid lp54, complete sequence	14305-14329	4	0.84
NC_008312_21	21.25|2628432|25|NC_008312|CRT	2628432-2628456	25	NC_017804	Borreliella garinii BgVir plasmid lp54, complete sequence	14743-14767	4	0.84
NC_008312_21	21.25|2628432|25|NC_008312|CRT	2628432-2628456	25	NZ_MK795207	Helicobacter pylori strain Yak16 plasmid pY16, complete sequence	3086-3110	4	0.84
NC_008312_21	21.25|2628432|25|NC_008312|CRT	2628432-2628456	25	MN694029	Marine virus AFVG_250M395, complete genome	21251-21275	4	0.84
NC_008312_21	21.28|2628549|25|NC_008312|CRT	2628549-2628573	25	NC_017364	Helicobacter pylori Gambia94/24 plasmid, complete sequence	2033-2057	4	0.84
NC_008312_21	21.28|2628549|25|NC_008312|CRT	2628549-2628573	25	NC_017377	Helicobacter pylori Puno120 plasmid pHPPN120, complete sequence	5693-5717	4	0.84
NC_008312_21	21.28|2628549|25|NC_008312|CRT	2628549-2628573	25	NC_013547	Helicobacter pylori plasmid pAL226, complete sequence	9713-9737	4	0.84
NC_008312_21	21.28|2628549|25|NC_008312|CRT	2628549-2628573	25	AP018320	Nostoc sp. HK-01 plasmid plasmid2 DNA, complete genome	223896-223920	4	0.84
NC_008312_21	21.28|2628549|25|NC_008312|CRT	2628549-2628573	25	KF751797	Campylobacter phage CJIE4-5, complete genome	20821-20845	4	0.84
NC_008312_21	21.28|2628549|25|NC_008312|CRT	2628549-2628573	25	KF751794	Campylobacter phage CJIE4-2, complete genome	20574-20598	4	0.84
NC_008312_21	21.28|2628549|25|NC_008312|CRT	2628549-2628573	25	KF751795	Campylobacter phage CJIE4-3, complete genome	18827-18851	4	0.84
NC_008312_21	21.28|2628549|25|NC_008312|CRT	2628549-2628573	25	KF751796	Campylobacter phage CJIE4-4, complete genome	18865-18889	4	0.84
NC_008312_21	21.28|2628549|25|NC_008312|CRT	2628549-2628573	25	KF751793	Campylobacter phage CJIE4-1, complete genome	21768-21792	4	0.84
NC_008312_21	21.28|2628549|25|NC_008312|CRT	2628549-2628573	25	NZ_CP019854	Borreliella burgdorferi plasmid lp54, complete sequence	49055-49079	4	0.84
NC_008312_21	21.28|2628549|25|NC_008312|CRT	2628549-2628573	25	NZ_CP019765	Borreliella burgdorferi strain B31_NRZ isolate B31 plasmid p_lp54, complete sequence	49055-49079	4	0.84
NC_008312_21	21.28|2628549|25|NC_008312|CRT	2628549-2628573	25	NC_011784	Borreliella burgdorferi ZS7 plasmid ZS7_lp54, complete sequence	49040-49064	4	0.84
NC_008312_21	21.28|2628549|25|NC_008312|CRT	2628549-2628573	25	NC_001857	Borreliella burgdorferi B31 plasmid lp54, complete sequence	49062-49086	4	0.84
NC_008312_21	21.31|2628666|26|NC_008312|CRT	2628666-2628691	26	NZ_CP011146	Bacillus cereus strain FORC_013 plasmid pFORC13, complete sequence	23102-23127	4	0.846
NC_008312_21	21.31|2628666|26|NC_008312|CRT	2628666-2628691	26	MN693653	Marine virus AFVG_250M591, complete genome	26889-26914	4	0.846
NC_008312_21	21.38|2628979|26|NC_008312|CRT	2628979-2629004	26	KY926699	Lactococcus phage PLgY-30, complete genome	7089-7114	4	0.846
NC_008312_21	21.38|2628979|26|NC_008312|CRT	2628979-2629004	26	KY888143	Lactococcus phage PLgW-1, complete genome	7147-7172	4	0.846
NC_008312_21	21.38|2628979|26|NC_008312|CRT	2628979-2629004	26	KY926698	Lactococcus phage PLgY-16, complete genome	7147-7172	4	0.846
NC_008312_21	21.42|2629161|26|NC_008312|CRT	2629161-2629186	26	KY926699	Lactococcus phage PLgY-30, complete genome	7089-7114	4	0.846
NC_008312_21	21.42|2629161|26|NC_008312|CRT	2629161-2629186	26	KY888143	Lactococcus phage PLgW-1, complete genome	7147-7172	4	0.846
NC_008312_21	21.42|2629161|26|NC_008312|CRT	2629161-2629186	26	KY926698	Lactococcus phage PLgY-16, complete genome	7147-7172	4	0.846
NC_008312_21	21.58|2630150|26|NC_008312|CRT	2630150-2630175	26	KY926699	Lactococcus phage PLgY-30, complete genome	7089-7114	4	0.846
NC_008312_21	21.58|2630150|26|NC_008312|CRT	2630150-2630175	26	KY888143	Lactococcus phage PLgW-1, complete genome	7147-7172	4	0.846
NC_008312_21	21.58|2630150|26|NC_008312|CRT	2630150-2630175	26	KY926698	Lactococcus phage PLgY-16, complete genome	7147-7172	4	0.846
NC_008312_23	23.1|2941370|38|NC_008312|CRT	2941370-2941407	38	NZ_CP015730	Bacillus cereus strain A1 plasmid pBCA1, complete sequence	77621-77658	4	0.895
NC_008312_48	48.4|7295333|25|NC_008312|CRISPRCasFinder	7295333-7295357	25	KU686211	Synechococcus phage S-WAM2 isolate 0810PA29, complete genome	172240-172264	4	0.84
NC_008312_48	48.4|7295333|25|NC_008312|CRISPRCasFinder	7295333-7295357	25	MT162468	Synechococcus phage S-H25, complete genome	133187-133211	4	0.84
NC_008312_48	48.4|7295333|25|NC_008312|CRISPRCasFinder	7295333-7295357	25	NC_031944	Synechococcus phage S-WAM1 isolate 0810PA09, complete genome	138162-138186	4	0.84
NC_008312_48	48.4|7295333|25|NC_008312|CRISPRCasFinder	7295333-7295357	25	MW117966	Synechococcus phage S-H9-1, complete genome	66068-66092	4	0.84
NC_008312_48	48.4|7295333|25|NC_008312|CRISPRCasFinder	7295333-7295357	25	NC_013085	Synechococcus phage S-RSM4, complete genome	14345-14369	4	0.84
NC_008312_48	48.4|7295333|25|NC_008312|CRISPRCasFinder	7295333-7295357	25	FM207411	Synechococcus phage S-RSM4 complete genome	14345-14369	4	0.84
NC_008312_3	3.4|613093|29|NC_008312|CRT	613093-613121	29	NC_041958	Roseobacter phage RDJL Phi 2, complete genome	36188-36216	5	0.828
NC_008312_3	3.22|614119|29|NC_008312|CRT	614119-614147	29	NZ_CP022775	Ralstonia solanacearum strain T12 plasmid unnamed, complete sequence	242920-242948	5	0.828
NC_008312_3	3.22|614119|29|NC_008312|CRT	614119-614147	29	NC_014310	Ralstonia solanacearum PSI07 plasmid mpPSI07, complete sequence	236915-236943	5	0.828
NC_008312_3	3.22|614119|29|NC_008312|CRT	614119-614147	29	NZ_CP022762	Ralstonia solanacearum strain T95 plasmid unnamed, complete sequence	247061-247089	5	0.828
NC_008312_3	3.22|614119|29|NC_008312|CRT	614119-614147	29	NZ_CP023017	Ralstonia solanacearum strain SL3022 plasmid unnamed, complete sequence	230475-230503	5	0.828
NC_008312_3	3.22|614119|29|NC_008312|CRT	614119-614147	29	NZ_CP014703	Ralstonia solanacearum strain KACC 10722 plasmid, complete sequence	247061-247089	5	0.828
NC_008312_3	3.22|614119|29|NC_008312|CRT	614119-614147	29	NZ_CP022760	Ralstonia solanacearum strain T98 plasmid unnamed, complete sequence	240783-240811	5	0.828
NC_008312_3	3.22|614119|29|NC_008312|CRT	614119-614147	29	NZ_CP022789	Ralstonia solanacearum strain SL3175 plasmid unnamed, complete sequence	240772-240800	5	0.828
NC_008312_3	3.22|614119|29|NC_008312|CRT	614119-614147	29	NZ_CP022771	Ralstonia solanacearum strain T51 plasmid unnamed, complete sequence	247066-247094	5	0.828
NC_008312_3	3.22|614119|29|NC_008312|CRT	614119-614147	29	NZ_CP022777	Ralstonia solanacearum strain T11 plasmid unnamed, complete sequence	247088-247116	5	0.828
NC_008312_3	3.22|614119|29|NC_008312|CRT	614119-614147	29	NZ_CP022799	Ralstonia solanacearum strain SL2064 plasmid unnamed, complete sequence	247060-247088	5	0.828
NC_008312_3	3.22|614119|29|NC_008312|CRT	614119-614147	29	NZ_CP022764	Ralstonia solanacearum strain T82 plasmid unnamed, complete sequence	242941-242969	5	0.828
NC_008312_3	3.22|614119|29|NC_008312|CRT	614119-614147	29	NZ_CP022797	Ralstonia solanacearum strain SL2312 plasmid unnamed, complete sequence	242939-242967	5	0.828
NC_008312_3	3.22|614119|29|NC_008312|CRT	614119-614147	29	NZ_CP022758	Ralstonia solanacearum strain T101 plasmid unnamed, complete sequence	242935-242963	5	0.828
NC_008312_3	3.24|614218|29|NC_008312|CRT	614218-614246	29	NZ_CP012940	Ralstonia solanacearum strain UW163 plasmid unnamed, complete sequence	1742674-1742702	5	0.828
NC_008312_3	3.24|614218|29|NC_008312|CRT	614218-614246	29	NZ_CP012944	Ralstonia solanacearum strain IBSBF1503 plasmid unnamed, complete sequence	1759388-1759416	5	0.828
NC_008312_3	3.24|614218|29|NC_008312|CRT	614218-614246	29	NZ_CP051295	Ralstonia solanacearum strain CIAT_078 plasmid megaplasmid, complete sequence	1722589-1722617	5	0.828
NC_008312_3	3.24|614218|29|NC_008312|CRT	614218-614246	29	NZ_CP026091	Ralstonia solanacearum strain IBSBF 2570 plasmid unnamed, complete sequence	259841-259869	5	0.828
NC_008312_3	3.24|614218|29|NC_008312|CRT	614218-614246	29	NC_014309	Ralstonia solanacearum CFBP2957 plasmid RCFBPv3_mp, complete genome	259262-259290	5	0.828
NC_008312_3	3.24|614218|29|NC_008312|CRT	614218-614246	29	NZ_CP021653	Ralstonia solanacearum strain RS 488 plasmid unnamed, complete sequence	462852-462880	5	0.828
NC_008312_3	3.24|614218|29|NC_008312|CRT	614218-614246	29	NZ_CP026093	Ralstonia solanacearum strain SFC plasmid unnamed, complete sequence	259832-259860	5	0.828
NC_008312_3	3.24|614218|29|NC_008312|CRT	614218-614246	29	NZ_CP021767	Ralstonia solanacearum strain RS 489 plasmid unnamed, complete sequence	462924-462952	5	0.828
NC_008312_3	3.24|614218|29|NC_008312|CRT	614218-614246	29	NZ_CP012688	Ralstonia solanacearum strain UY031 plasmid unnamed, complete sequence	462861-462889	5	0.828
NC_008312_3	3.24|614218|29|NC_008312|CRT	614218-614246	29	NC_017575	Ralstonia solanacearum Po82 megaplasmid, complete sequence	259654-259682	5	0.828
NC_008312_3	3.24|614218|29|NC_008312|CRT	614218-614246	29	NZ_CP026308	Ralstonia solanacearum strain IBSBF 2571 plasmid unnamed, complete sequence	259641-259669	5	0.828
NC_008312_3	3.24|614218|29|NC_008312|CRT	614218-614246	29	NZ_CP021765	Ralstonia pseudosolanacearum strain CRMRs218 plasmid unnamed, complete sequence	299777-299805	5	0.828
NC_008312_3	3.24|614218|29|NC_008312|CRT	614218-614246	29	CP047139	Ralstonia solanacearum strain CFBP 8695 plasmid unnamed, complete sequence	463052-463080	5	0.828
NC_008312_3	3.24|614218|29|NC_008312|CRT	614218-614246	29	CP047137	Ralstonia solanacearum strain CFBP 8697 plasmid unnamed, complete sequence	440108-440136	5	0.828
NC_008312_3	3.29|614479|29|NC_008312|CRT	614479-614507	29	NC_007501	Lactobacillus phage Lc-Nu, complete genome	16339-16367	5	0.828
NC_008312_3	3.29|614479|29|NC_008312|CRT	614479-614507	29	AY131267	Bacteriophage Lc-Nu, complete genome	16339-16367	5	0.828
NC_008312_3	3.29|614479|29|NC_008312|CRT	614479-614507	29	NC_017957	Tistrella mobilis KA081020-065 plasmid pTM1, complete sequence	235822-235850	5	0.828
NC_008312_3	3.33|614713|29|NC_008312|CRT	614713-614741	29	NZ_CP012940	Ralstonia solanacearum strain UW163 plasmid unnamed, complete sequence	1742674-1742702	5	0.828
NC_008312_3	3.33|614713|29|NC_008312|CRT	614713-614741	29	NZ_CP012944	Ralstonia solanacearum strain IBSBF1503 plasmid unnamed, complete sequence	1759388-1759416	5	0.828
NC_008312_3	3.33|614713|29|NC_008312|CRT	614713-614741	29	NZ_CP051295	Ralstonia solanacearum strain CIAT_078 plasmid megaplasmid, complete sequence	1722589-1722617	5	0.828
NC_008312_3	3.33|614713|29|NC_008312|CRT	614713-614741	29	NZ_CP026091	Ralstonia solanacearum strain IBSBF 2570 plasmid unnamed, complete sequence	259841-259869	5	0.828
NC_008312_3	3.33|614713|29|NC_008312|CRT	614713-614741	29	NC_014309	Ralstonia solanacearum CFBP2957 plasmid RCFBPv3_mp, complete genome	259262-259290	5	0.828
NC_008312_3	3.33|614713|29|NC_008312|CRT	614713-614741	29	NZ_CP021653	Ralstonia solanacearum strain RS 488 plasmid unnamed, complete sequence	462852-462880	5	0.828
NC_008312_3	3.33|614713|29|NC_008312|CRT	614713-614741	29	NZ_CP026093	Ralstonia solanacearum strain SFC plasmid unnamed, complete sequence	259832-259860	5	0.828
NC_008312_3	3.33|614713|29|NC_008312|CRT	614713-614741	29	NZ_CP021767	Ralstonia solanacearum strain RS 489 plasmid unnamed, complete sequence	462924-462952	5	0.828
NC_008312_3	3.33|614713|29|NC_008312|CRT	614713-614741	29	NZ_CP012688	Ralstonia solanacearum strain UY031 plasmid unnamed, complete sequence	462861-462889	5	0.828
NC_008312_3	3.33|614713|29|NC_008312|CRT	614713-614741	29	NC_017575	Ralstonia solanacearum Po82 megaplasmid, complete sequence	259654-259682	5	0.828
NC_008312_3	3.33|614713|29|NC_008312|CRT	614713-614741	29	NZ_CP026308	Ralstonia solanacearum strain IBSBF 2571 plasmid unnamed, complete sequence	259641-259669	5	0.828
NC_008312_3	3.33|614713|29|NC_008312|CRT	614713-614741	29	NZ_CP021765	Ralstonia pseudosolanacearum strain CRMRs218 plasmid unnamed, complete sequence	299777-299805	5	0.828
NC_008312_3	3.33|614713|29|NC_008312|CRT	614713-614741	29	CP047139	Ralstonia solanacearum strain CFBP 8695 plasmid unnamed, complete sequence	463052-463080	5	0.828
NC_008312_3	3.33|614713|29|NC_008312|CRT	614713-614741	29	CP047137	Ralstonia solanacearum strain CFBP 8697 plasmid unnamed, complete sequence	440108-440136	5	0.828
NC_008312_3	3.35|614830|29|NC_008312|CRT	614830-614858	29	NC_009128	Corynebacterium sp. L2-79-05 plasmid pLEW279a, complete sequence	16480-16508	5	0.828
NC_008312_3	3.35|614830|29|NC_008312|CRT	614830-614858	29	NZ_CP004352	Corynebacterium casei LMG S-19264 plasmid pCASE2, complete sequence	6920-6948	5	0.828
NC_008312_3	3.40|615091|29|NC_008312|CRT	615091-615119	29	NC_007501	Lactobacillus phage Lc-Nu, complete genome	16339-16367	5	0.828
NC_008312_3	3.40|615091|29|NC_008312|CRT	615091-615119	29	AY131267	Bacteriophage Lc-Nu, complete genome	16339-16367	5	0.828
NC_008312_3	3.40|615091|29|NC_008312|CRT	615091-615119	29	NC_017957	Tistrella mobilis KA081020-065 plasmid pTM1, complete sequence	235822-235850	5	0.828
NC_008312_3	3.45|615433|29|NC_008312|CRT	615433-615461	29	NC_009128	Corynebacterium sp. L2-79-05 plasmid pLEW279a, complete sequence	16480-16508	5	0.828
NC_008312_3	3.45|615433|29|NC_008312|CRT	615433-615461	29	NZ_CP004352	Corynebacterium casei LMG S-19264 plasmid pCASE2, complete sequence	6920-6948	5	0.828
NC_008312_4	4.2|617254|29|NC_008312|CRT	617254-617282	29	NZ_CP007797	Azospirillum brasilense strain Az39 plasmid AbAZ39_p4, complete sequence	189327-189355	5	0.828
NC_008312_4	4.3|617317|29|NC_008312|CRT	617317-617345	29	NZ_CP022775	Ralstonia solanacearum strain T12 plasmid unnamed, complete sequence	242920-242948	5	0.828
NC_008312_4	4.3|617317|29|NC_008312|CRT	617317-617345	29	NC_014310	Ralstonia solanacearum PSI07 plasmid mpPSI07, complete sequence	236915-236943	5	0.828
NC_008312_4	4.3|617317|29|NC_008312|CRT	617317-617345	29	NZ_CP022762	Ralstonia solanacearum strain T95 plasmid unnamed, complete sequence	247061-247089	5	0.828
NC_008312_4	4.3|617317|29|NC_008312|CRT	617317-617345	29	NZ_CP023017	Ralstonia solanacearum strain SL3022 plasmid unnamed, complete sequence	230475-230503	5	0.828
NC_008312_4	4.3|617317|29|NC_008312|CRT	617317-617345	29	NZ_CP014703	Ralstonia solanacearum strain KACC 10722 plasmid, complete sequence	247061-247089	5	0.828
NC_008312_4	4.3|617317|29|NC_008312|CRT	617317-617345	29	NZ_CP022760	Ralstonia solanacearum strain T98 plasmid unnamed, complete sequence	240783-240811	5	0.828
NC_008312_4	4.3|617317|29|NC_008312|CRT	617317-617345	29	NZ_CP022789	Ralstonia solanacearum strain SL3175 plasmid unnamed, complete sequence	240772-240800	5	0.828
NC_008312_4	4.3|617317|29|NC_008312|CRT	617317-617345	29	NZ_CP022771	Ralstonia solanacearum strain T51 plasmid unnamed, complete sequence	247066-247094	5	0.828
NC_008312_4	4.3|617317|29|NC_008312|CRT	617317-617345	29	NZ_CP022777	Ralstonia solanacearum strain T11 plasmid unnamed, complete sequence	247088-247116	5	0.828
NC_008312_4	4.3|617317|29|NC_008312|CRT	617317-617345	29	NZ_CP022799	Ralstonia solanacearum strain SL2064 plasmid unnamed, complete sequence	247060-247088	5	0.828
NC_008312_4	4.3|617317|29|NC_008312|CRT	617317-617345	29	NZ_CP022764	Ralstonia solanacearum strain T82 plasmid unnamed, complete sequence	242941-242969	5	0.828
NC_008312_4	4.3|617317|29|NC_008312|CRT	617317-617345	29	NZ_CP022797	Ralstonia solanacearum strain SL2312 plasmid unnamed, complete sequence	242939-242967	5	0.828
NC_008312_4	4.3|617317|29|NC_008312|CRT	617317-617345	29	NZ_CP022758	Ralstonia solanacearum strain T101 plasmid unnamed, complete sequence	242935-242963	5	0.828
NC_008312_4	4.5|617434|29|NC_008312|CRT	617434-617462	29	NZ_CP022775	Ralstonia solanacearum strain T12 plasmid unnamed, complete sequence	242920-242948	5	0.828
NC_008312_4	4.5|617434|29|NC_008312|CRT	617434-617462	29	NC_014310	Ralstonia solanacearum PSI07 plasmid mpPSI07, complete sequence	236915-236943	5	0.828
NC_008312_4	4.5|617434|29|NC_008312|CRT	617434-617462	29	NZ_CP022762	Ralstonia solanacearum strain T95 plasmid unnamed, complete sequence	247061-247089	5	0.828
NC_008312_4	4.5|617434|29|NC_008312|CRT	617434-617462	29	NZ_CP023017	Ralstonia solanacearum strain SL3022 plasmid unnamed, complete sequence	230475-230503	5	0.828
NC_008312_4	4.5|617434|29|NC_008312|CRT	617434-617462	29	NZ_CP014703	Ralstonia solanacearum strain KACC 10722 plasmid, complete sequence	247061-247089	5	0.828
NC_008312_4	4.5|617434|29|NC_008312|CRT	617434-617462	29	NZ_CP022760	Ralstonia solanacearum strain T98 plasmid unnamed, complete sequence	240783-240811	5	0.828
NC_008312_4	4.5|617434|29|NC_008312|CRT	617434-617462	29	NZ_CP022789	Ralstonia solanacearum strain SL3175 plasmid unnamed, complete sequence	240772-240800	5	0.828
NC_008312_4	4.5|617434|29|NC_008312|CRT	617434-617462	29	NZ_CP022771	Ralstonia solanacearum strain T51 plasmid unnamed, complete sequence	247066-247094	5	0.828
NC_008312_4	4.5|617434|29|NC_008312|CRT	617434-617462	29	NZ_CP022777	Ralstonia solanacearum strain T11 plasmid unnamed, complete sequence	247088-247116	5	0.828
NC_008312_4	4.5|617434|29|NC_008312|CRT	617434-617462	29	NZ_CP022799	Ralstonia solanacearum strain SL2064 plasmid unnamed, complete sequence	247060-247088	5	0.828
NC_008312_4	4.5|617434|29|NC_008312|CRT	617434-617462	29	NZ_CP022764	Ralstonia solanacearum strain T82 plasmid unnamed, complete sequence	242941-242969	5	0.828
NC_008312_4	4.5|617434|29|NC_008312|CRT	617434-617462	29	NZ_CP022797	Ralstonia solanacearum strain SL2312 plasmid unnamed, complete sequence	242939-242967	5	0.828
NC_008312_4	4.5|617434|29|NC_008312|CRT	617434-617462	29	NZ_CP022758	Ralstonia solanacearum strain T101 plasmid unnamed, complete sequence	242935-242963	5	0.828
NC_008312_12	12.14|1607246|27|NC_008312|CRT	1607246-1607272	27	NC_011738	Gloeothece citriformis PCC 7424 plasmid pP742401, complete sequence	115384-115410	5	0.815
NC_008312_12	12.14|1607246|27|NC_008312|CRT	1607246-1607272	27	NC_004565	Clostridium tetani E88 plasmid pE88, complete sequence	16990-17016	5	0.815
NC_008312_12	12.14|1607246|27|NC_008312|CRT	1607246-1607272	27	NC_004565	Clostridium tetani E88 plasmid pE88, complete sequence	47928-47954	5	0.815
NC_008312_12	12.14|1607246|27|NC_008312|CRT	1607246-1607272	27	CP011075	Brevibacillus laterosporus strain B9 plasmid unnamed1, complete sequence	716135-716161	5	0.815
NC_008312_12	12.14|1607246|27|NC_008312|CRT	1607246-1607272	27	NZ_CP039730	Enterococcus faecium strain ZY2 plasmid pZY2	73568-73594	5	0.815
NC_008312_12	12.14|1607246|27|NC_008312|CRT	1607246-1607272	27	NZ_CP009921	Bacillus megaterium NBRC 15308 = ATCC 14581 plasmid pBMV_2, complete sequence	282016-282042	5	0.815
NC_008312_12	12.14|1607246|27|NC_008312|CRT	1607246-1607272	27	NZ_MG640601	Enterococcus faecium strain SRR6 plasmid pEMSRR6, complete sequence	79336-79362	5	0.815
NC_008312_12	12.14|1607246|27|NC_008312|CRT	1607246-1607272	27	NZ_CP035095	Bacillus megaterium NBRC 15308 = ATCC 14581 plasmid unnamed1, complete sequence	194929-194955	5	0.815
NC_008312_12	12.14|1607246|27|NC_008312|CRT	1607246-1607272	27	MK448842	Streptococcus phage Javan110, complete genome	11373-11399	5	0.815
NC_008312_21	21.19|2628169|26|NC_008312|CRT	2628169-2628194	26	MK448601	Streptococcus satellite phage Javan653, complete genome	8469-8494	5	0.808
NC_008312_21	21.21|2628250|26|NC_008312|CRT	2628250-2628275	26	MK448601	Streptococcus satellite phage Javan653, complete genome	8469-8494	5	0.808
NC_008312_21	21.32|2628710|26|NC_008312|CRT	2628710-2628735	26	MN693047	Marine virus AFVG_25M111, complete genome	33209-33234	5	0.808
NC_008312_21	21.32|2628710|26|NC_008312|CRT	2628710-2628735	26	MN693506	Marine virus AFVG_25M112, complete genome	32970-32995	5	0.808
NC_008312_21	21.32|2628710|26|NC_008312|CRT	2628710-2628735	26	NZ_CP029750	Staphylococcus aureus strain Smith plasmid pSS41, complete sequence	38999-39024	5	0.808
NC_008312_21	21.51|2629736|40|NC_008312|CRT	2629736-2629775	40	NC_015511	Haliscomenobacter hydrossis DSM 1100 plasmid pHALHY01, complete sequence	2195-2234	5	0.875
NC_008312_29	29.1|3671521|26|NC_008312|CRISPRCasFinder	3671521-3671546	26	NZ_CP028970	Aminobacter sp. MSH1 plasmid pUSP2, complete sequence	87213-87238	5	0.808
NC_008312_45	45.6|6864734|30|NC_008312|CRT	6864734-6864763	30	NZ_CP048816	Caulobacter rhizosphaerae strain KCTC 52515 plasmid unnamed	137470-137499	5	0.833
NC_008312_45	45.6|6864734|30|NC_008312|CRT	6864734-6864763	30	NZ_CP022365	Azospirillum sp. TSH58 plasmid TSH58_p06, complete sequence	26718-26747	5	0.833
NC_008312_47	47.1|7278276|30|NC_008312|CRISPRCasFinder	7278276-7278305	30	NZ_CP021887	Helicobacter apodemus strain SCJK1 plasmid unnamed, complete sequence	22874-22903	5	0.833
NC_008312_48	48.1|7295144|25|NC_008312|CRISPRCasFinder	7295144-7295168	25	NZ_CP048608	Pseudomonas fluorescens strain DR133 plasmid unnamed, complete sequence	10925-10949	5	0.8
NC_008312_3	3.4|613093|29|NC_008312|CRT	613093-613121	29	AY939844	Prochlorococcus phage P-SSM2, complete genome	21008-21036	6	0.793
NC_008312_3	3.4|613093|29|NC_008312|CRT	613093-613121	29	NC_017957	Tistrella mobilis KA081020-065 plasmid pTM1, complete sequence	235822-235850	6	0.793
NC_008312_3	3.4|613093|29|NC_008312|CRT	613093-613121	29	HQ632825	Prochlorococcus phage P-SSM5 genomic sequence	65946-65974	6	0.793
NC_008312_3	3.4|613093|29|NC_008312|CRT	613093-613121	29	MN116494	Klebsiella phage vB_KpnP_Bp5, complete genome	13826-13854	6	0.793
NC_008312_3	3.4|613093|29|NC_008312|CRT	613093-613121	29	NZ_CP053445	Rhizobium leguminosarum bv. trifolii strain CC275e plasmid pRltCC275eA, complete sequence	23967-23995	6	0.793
NC_008312_3	3.22|614119|29|NC_008312|CRT	614119-614147	29	NZ_CP033220	Parasedimentitalea marina strain W43 plasmid pW43A, complete sequence	41156-41184	6	0.793
NC_008312_3	3.22|614119|29|NC_008312|CRT	614119-614147	29	NZ_CP033220	Parasedimentitalea marina strain W43 plasmid pW43A, complete sequence	122866-122894	6	0.793
NC_008312_3	3.22|614119|29|NC_008312|CRT	614119-614147	29	NZ_CP006909	Clostridium botulinum CDC_1436 plasmid pCBG, complete sequence	211066-211094	6	0.793
NC_008312_3	3.22|614119|29|NC_008312|CRT	614119-614147	29	NZ_CP031095	Clostridium botulinum strain CFSAN034200 plasmid p1_CDC51232, complete sequence	81534-81562	6	0.793
NC_008312_3	3.22|614119|29|NC_008312|CRT	614119-614147	29	NC_009128	Corynebacterium sp. L2-79-05 plasmid pLEW279a, complete sequence	16480-16508	6	0.793
NC_008312_3	3.22|614119|29|NC_008312|CRT	614119-614147	29	NZ_CP004352	Corynebacterium casei LMG S-19264 plasmid pCASE2, complete sequence	6920-6948	6	0.793
NC_008312_3	3.22|614119|29|NC_008312|CRT	614119-614147	29	NC_012654	Clostridium botulinum Ba4 str. 657 plasmid pCLJ, complete sequence	30599-30627	6	0.793
NC_008312_3	3.22|614119|29|NC_008312|CRT	614119-614147	29	NZ_CP034811	Paracoccus sp. Arc7-R13 plasmid unnamed1, complete sequence	147811-147839	6	0.793
NC_008312_3	3.22|614119|29|NC_008312|CRT	614119-614147	29	NC_028835	Lactobacillus phage CL2, complete genome	17509-17537	6	0.793
NC_008312_3	3.22|614119|29|NC_008312|CRT	614119-614147	29	KR905066	Lactobacillus phage CL1, complete genome	16494-16522	6	0.793
NC_008312_3	3.22|614119|29|NC_008312|CRT	614119-614147	29	NC_028911	Lactobacillus phage iLp1308, complete genome	16202-16230	6	0.793
NC_008312_3	3.24|614218|29|NC_008312|CRT	614218-614246	29	NC_007501	Lactobacillus phage Lc-Nu, complete genome	16339-16367	6	0.793
NC_008312_3	3.24|614218|29|NC_008312|CRT	614218-614246	29	AY131267	Bacteriophage Lc-Nu, complete genome	16339-16367	6	0.793
NC_008312_3	3.24|614218|29|NC_008312|CRT	614218-614246	29	NZ_CP022775	Ralstonia solanacearum strain T12 plasmid unnamed, complete sequence	242920-242948	6	0.793
NC_008312_3	3.24|614218|29|NC_008312|CRT	614218-614246	29	NC_014310	Ralstonia solanacearum PSI07 plasmid mpPSI07, complete sequence	236915-236943	6	0.793
NC_008312_3	3.24|614218|29|NC_008312|CRT	614218-614246	29	NZ_CP022762	Ralstonia solanacearum strain T95 plasmid unnamed, complete sequence	247061-247089	6	0.793
NC_008312_3	3.24|614218|29|NC_008312|CRT	614218-614246	29	NZ_CP023017	Ralstonia solanacearum strain SL3022 plasmid unnamed, complete sequence	230475-230503	6	0.793
NC_008312_3	3.24|614218|29|NC_008312|CRT	614218-614246	29	NZ_CP014703	Ralstonia solanacearum strain KACC 10722 plasmid, complete sequence	247061-247089	6	0.793
NC_008312_3	3.24|614218|29|NC_008312|CRT	614218-614246	29	NZ_CP022760	Ralstonia solanacearum strain T98 plasmid unnamed, complete sequence	240783-240811	6	0.793
NC_008312_3	3.24|614218|29|NC_008312|CRT	614218-614246	29	NZ_CP022789	Ralstonia solanacearum strain SL3175 plasmid unnamed, complete sequence	240772-240800	6	0.793
NC_008312_3	3.24|614218|29|NC_008312|CRT	614218-614246	29	NZ_CP022771	Ralstonia solanacearum strain T51 plasmid unnamed, complete sequence	247066-247094	6	0.793
NC_008312_3	3.24|614218|29|NC_008312|CRT	614218-614246	29	NZ_CP022777	Ralstonia solanacearum strain T11 plasmid unnamed, complete sequence	247088-247116	6	0.793
NC_008312_3	3.24|614218|29|NC_008312|CRT	614218-614246	29	NZ_CP022799	Ralstonia solanacearum strain SL2064 plasmid unnamed, complete sequence	247060-247088	6	0.793
NC_008312_3	3.24|614218|29|NC_008312|CRT	614218-614246	29	NZ_CP022764	Ralstonia solanacearum strain T82 plasmid unnamed, complete sequence	242941-242969	6	0.793
NC_008312_3	3.24|614218|29|NC_008312|CRT	614218-614246	29	NZ_CP022797	Ralstonia solanacearum strain SL2312 plasmid unnamed, complete sequence	242939-242967	6	0.793
NC_008312_3	3.24|614218|29|NC_008312|CRT	614218-614246	29	NZ_CP022758	Ralstonia solanacearum strain T101 plasmid unnamed, complete sequence	242935-242963	6	0.793
NC_008312_3	3.24|614218|29|NC_008312|CRT	614218-614246	29	NZ_CP033220	Parasedimentitalea marina strain W43 plasmid pW43A, complete sequence	41156-41184	6	0.793
NC_008312_3	3.24|614218|29|NC_008312|CRT	614218-614246	29	NZ_CP033220	Parasedimentitalea marina strain W43 plasmid pW43A, complete sequence	122866-122894	6	0.793
NC_008312_3	3.29|614479|29|NC_008312|CRT	614479-614507	29	NZ_CP012940	Ralstonia solanacearum strain UW163 plasmid unnamed, complete sequence	1742674-1742702	6	0.793
NC_008312_3	3.29|614479|29|NC_008312|CRT	614479-614507	29	NZ_CP012944	Ralstonia solanacearum strain IBSBF1503 plasmid unnamed, complete sequence	1759388-1759416	6	0.793
NC_008312_3	3.29|614479|29|NC_008312|CRT	614479-614507	29	NZ_CP051295	Ralstonia solanacearum strain CIAT_078 plasmid megaplasmid, complete sequence	1722589-1722617	6	0.793
NC_008312_3	3.29|614479|29|NC_008312|CRT	614479-614507	29	NZ_CP026091	Ralstonia solanacearum strain IBSBF 2570 plasmid unnamed, complete sequence	259841-259869	6	0.793
NC_008312_3	3.29|614479|29|NC_008312|CRT	614479-614507	29	NC_014309	Ralstonia solanacearum CFBP2957 plasmid RCFBPv3_mp, complete genome	259262-259290	6	0.793
NC_008312_3	3.29|614479|29|NC_008312|CRT	614479-614507	29	NZ_CP021653	Ralstonia solanacearum strain RS 488 plasmid unnamed, complete sequence	462852-462880	6	0.793
NC_008312_3	3.29|614479|29|NC_008312|CRT	614479-614507	29	NZ_CP026093	Ralstonia solanacearum strain SFC plasmid unnamed, complete sequence	259832-259860	6	0.793
NC_008312_3	3.29|614479|29|NC_008312|CRT	614479-614507	29	NZ_CP021767	Ralstonia solanacearum strain RS 489 plasmid unnamed, complete sequence	462924-462952	6	0.793
NC_008312_3	3.29|614479|29|NC_008312|CRT	614479-614507	29	NZ_CP012688	Ralstonia solanacearum strain UY031 plasmid unnamed, complete sequence	462861-462889	6	0.793
NC_008312_3	3.29|614479|29|NC_008312|CRT	614479-614507	29	NC_017575	Ralstonia solanacearum Po82 megaplasmid, complete sequence	259654-259682	6	0.793
NC_008312_3	3.29|614479|29|NC_008312|CRT	614479-614507	29	NZ_CP026308	Ralstonia solanacearum strain IBSBF 2571 plasmid unnamed, complete sequence	259641-259669	6	0.793
NC_008312_3	3.29|614479|29|NC_008312|CRT	614479-614507	29	NZ_CP021765	Ralstonia pseudosolanacearum strain CRMRs218 plasmid unnamed, complete sequence	299777-299805	6	0.793
NC_008312_3	3.29|614479|29|NC_008312|CRT	614479-614507	29	CP047139	Ralstonia solanacearum strain CFBP 8695 plasmid unnamed, complete sequence	463052-463080	6	0.793
NC_008312_3	3.29|614479|29|NC_008312|CRT	614479-614507	29	CP047137	Ralstonia solanacearum strain CFBP 8697 plasmid unnamed, complete sequence	440108-440136	6	0.793
NC_008312_3	3.29|614479|29|NC_008312|CRT	614479-614507	29	NZ_CP033220	Parasedimentitalea marina strain W43 plasmid pW43A, complete sequence	41156-41184	6	0.793
NC_008312_3	3.29|614479|29|NC_008312|CRT	614479-614507	29	NZ_CP033220	Parasedimentitalea marina strain W43 plasmid pW43A, complete sequence	122866-122894	6	0.793
NC_008312_3	3.29|614479|29|NC_008312|CRT	614479-614507	29	NC_009128	Corynebacterium sp. L2-79-05 plasmid pLEW279a, complete sequence	16480-16508	6	0.793
NC_008312_3	3.29|614479|29|NC_008312|CRT	614479-614507	29	NZ_CP004352	Corynebacterium casei LMG S-19264 plasmid pCASE2, complete sequence	6920-6948	6	0.793
NC_008312_3	3.33|614713|29|NC_008312|CRT	614713-614741	29	NC_007501	Lactobacillus phage Lc-Nu, complete genome	16339-16367	6	0.793
NC_008312_3	3.33|614713|29|NC_008312|CRT	614713-614741	29	AY131267	Bacteriophage Lc-Nu, complete genome	16339-16367	6	0.793
NC_008312_3	3.33|614713|29|NC_008312|CRT	614713-614741	29	NZ_CP022775	Ralstonia solanacearum strain T12 plasmid unnamed, complete sequence	242920-242948	6	0.793
NC_008312_3	3.33|614713|29|NC_008312|CRT	614713-614741	29	NC_014310	Ralstonia solanacearum PSI07 plasmid mpPSI07, complete sequence	236915-236943	6	0.793
NC_008312_3	3.33|614713|29|NC_008312|CRT	614713-614741	29	NZ_CP022762	Ralstonia solanacearum strain T95 plasmid unnamed, complete sequence	247061-247089	6	0.793
NC_008312_3	3.33|614713|29|NC_008312|CRT	614713-614741	29	NZ_CP023017	Ralstonia solanacearum strain SL3022 plasmid unnamed, complete sequence	230475-230503	6	0.793
NC_008312_3	3.33|614713|29|NC_008312|CRT	614713-614741	29	NZ_CP014703	Ralstonia solanacearum strain KACC 10722 plasmid, complete sequence	247061-247089	6	0.793
NC_008312_3	3.33|614713|29|NC_008312|CRT	614713-614741	29	NZ_CP022760	Ralstonia solanacearum strain T98 plasmid unnamed, complete sequence	240783-240811	6	0.793
NC_008312_3	3.33|614713|29|NC_008312|CRT	614713-614741	29	NZ_CP022789	Ralstonia solanacearum strain SL3175 plasmid unnamed, complete sequence	240772-240800	6	0.793
NC_008312_3	3.33|614713|29|NC_008312|CRT	614713-614741	29	NZ_CP022771	Ralstonia solanacearum strain T51 plasmid unnamed, complete sequence	247066-247094	6	0.793
NC_008312_3	3.33|614713|29|NC_008312|CRT	614713-614741	29	NZ_CP022777	Ralstonia solanacearum strain T11 plasmid unnamed, complete sequence	247088-247116	6	0.793
NC_008312_3	3.33|614713|29|NC_008312|CRT	614713-614741	29	NZ_CP022799	Ralstonia solanacearum strain SL2064 plasmid unnamed, complete sequence	247060-247088	6	0.793
NC_008312_3	3.33|614713|29|NC_008312|CRT	614713-614741	29	NZ_CP022764	Ralstonia solanacearum strain T82 plasmid unnamed, complete sequence	242941-242969	6	0.793
NC_008312_3	3.33|614713|29|NC_008312|CRT	614713-614741	29	NZ_CP022797	Ralstonia solanacearum strain SL2312 plasmid unnamed, complete sequence	242939-242967	6	0.793
NC_008312_3	3.33|614713|29|NC_008312|CRT	614713-614741	29	NZ_CP022758	Ralstonia solanacearum strain T101 plasmid unnamed, complete sequence	242935-242963	6	0.793
NC_008312_3	3.33|614713|29|NC_008312|CRT	614713-614741	29	NZ_CP033220	Parasedimentitalea marina strain W43 plasmid pW43A, complete sequence	41156-41184	6	0.793
NC_008312_3	3.33|614713|29|NC_008312|CRT	614713-614741	29	NZ_CP033220	Parasedimentitalea marina strain W43 plasmid pW43A, complete sequence	122866-122894	6	0.793
NC_008312_3	3.35|614830|29|NC_008312|CRT	614830-614858	29	NC_007501	Lactobacillus phage Lc-Nu, complete genome	16339-16367	6	0.793
NC_008312_3	3.35|614830|29|NC_008312|CRT	614830-614858	29	AY131267	Bacteriophage Lc-Nu, complete genome	16339-16367	6	0.793
NC_008312_3	3.35|614830|29|NC_008312|CRT	614830-614858	29	NZ_CP022775	Ralstonia solanacearum strain T12 plasmid unnamed, complete sequence	242920-242948	6	0.793
NC_008312_3	3.35|614830|29|NC_008312|CRT	614830-614858	29	NC_014310	Ralstonia solanacearum PSI07 plasmid mpPSI07, complete sequence	236915-236943	6	0.793
NC_008312_3	3.35|614830|29|NC_008312|CRT	614830-614858	29	NZ_CP022762	Ralstonia solanacearum strain T95 plasmid unnamed, complete sequence	247061-247089	6	0.793
NC_008312_3	3.35|614830|29|NC_008312|CRT	614830-614858	29	NZ_CP023017	Ralstonia solanacearum strain SL3022 plasmid unnamed, complete sequence	230475-230503	6	0.793
NC_008312_3	3.35|614830|29|NC_008312|CRT	614830-614858	29	NZ_CP014703	Ralstonia solanacearum strain KACC 10722 plasmid, complete sequence	247061-247089	6	0.793
NC_008312_3	3.35|614830|29|NC_008312|CRT	614830-614858	29	NZ_CP022760	Ralstonia solanacearum strain T98 plasmid unnamed, complete sequence	240783-240811	6	0.793
NC_008312_3	3.35|614830|29|NC_008312|CRT	614830-614858	29	NZ_CP022789	Ralstonia solanacearum strain SL3175 plasmid unnamed, complete sequence	240772-240800	6	0.793
NC_008312_3	3.35|614830|29|NC_008312|CRT	614830-614858	29	NZ_CP022771	Ralstonia solanacearum strain T51 plasmid unnamed, complete sequence	247066-247094	6	0.793
NC_008312_3	3.35|614830|29|NC_008312|CRT	614830-614858	29	NZ_CP022777	Ralstonia solanacearum strain T11 plasmid unnamed, complete sequence	247088-247116	6	0.793
NC_008312_3	3.35|614830|29|NC_008312|CRT	614830-614858	29	NZ_CP022799	Ralstonia solanacearum strain SL2064 plasmid unnamed, complete sequence	247060-247088	6	0.793
NC_008312_3	3.35|614830|29|NC_008312|CRT	614830-614858	29	NZ_CP022764	Ralstonia solanacearum strain T82 plasmid unnamed, complete sequence	242941-242969	6	0.793
NC_008312_3	3.35|614830|29|NC_008312|CRT	614830-614858	29	NZ_CP022797	Ralstonia solanacearum strain SL2312 plasmid unnamed, complete sequence	242939-242967	6	0.793
NC_008312_3	3.35|614830|29|NC_008312|CRT	614830-614858	29	NZ_CP022758	Ralstonia solanacearum strain T101 plasmid unnamed, complete sequence	242935-242963	6	0.793
NC_008312_3	3.35|614830|29|NC_008312|CRT	614830-614858	29	NC_012654	Clostridium botulinum Ba4 str. 657 plasmid pCLJ, complete sequence	30599-30627	6	0.793
NC_008312_3	3.35|614830|29|NC_008312|CRT	614830-614858	29	NZ_CP034811	Paracoccus sp. Arc7-R13 plasmid unnamed1, complete sequence	147811-147839	6	0.793
NC_008312_3	3.35|614830|29|NC_008312|CRT	614830-614858	29	NC_028835	Lactobacillus phage CL2, complete genome	17509-17537	6	0.793
NC_008312_3	3.35|614830|29|NC_008312|CRT	614830-614858	29	KR905066	Lactobacillus phage CL1, complete genome	16494-16522	6	0.793
NC_008312_3	3.35|614830|29|NC_008312|CRT	614830-614858	29	NC_028911	Lactobacillus phage iLp1308, complete genome	16202-16230	6	0.793
NC_008312_3	3.35|614830|29|NC_008312|CRT	614830-614858	29	NZ_CP033220	Parasedimentitalea marina strain W43 plasmid pW43A, complete sequence	41156-41184	6	0.793
NC_008312_3	3.35|614830|29|NC_008312|CRT	614830-614858	29	NZ_CP033220	Parasedimentitalea marina strain W43 plasmid pW43A, complete sequence	122866-122894	6	0.793
NC_008312_3	3.35|614830|29|NC_008312|CRT	614830-614858	29	NZ_CP006909	Clostridium botulinum CDC_1436 plasmid pCBG, complete sequence	211066-211094	6	0.793
NC_008312_3	3.35|614830|29|NC_008312|CRT	614830-614858	29	NZ_CP031095	Clostridium botulinum strain CFSAN034200 plasmid p1_CDC51232, complete sequence	81534-81562	6	0.793
NC_008312_3	3.40|615091|29|NC_008312|CRT	615091-615119	29	NZ_CP012940	Ralstonia solanacearum strain UW163 plasmid unnamed, complete sequence	1742674-1742702	6	0.793
NC_008312_3	3.40|615091|29|NC_008312|CRT	615091-615119	29	NZ_CP012944	Ralstonia solanacearum strain IBSBF1503 plasmid unnamed, complete sequence	1759388-1759416	6	0.793
NC_008312_3	3.40|615091|29|NC_008312|CRT	615091-615119	29	NZ_CP051295	Ralstonia solanacearum strain CIAT_078 plasmid megaplasmid, complete sequence	1722589-1722617	6	0.793
NC_008312_3	3.40|615091|29|NC_008312|CRT	615091-615119	29	NZ_CP026091	Ralstonia solanacearum strain IBSBF 2570 plasmid unnamed, complete sequence	259841-259869	6	0.793
NC_008312_3	3.40|615091|29|NC_008312|CRT	615091-615119	29	NC_014309	Ralstonia solanacearum CFBP2957 plasmid RCFBPv3_mp, complete genome	259262-259290	6	0.793
NC_008312_3	3.40|615091|29|NC_008312|CRT	615091-615119	29	NZ_CP021653	Ralstonia solanacearum strain RS 488 plasmid unnamed, complete sequence	462852-462880	6	0.793
NC_008312_3	3.40|615091|29|NC_008312|CRT	615091-615119	29	NZ_CP026093	Ralstonia solanacearum strain SFC plasmid unnamed, complete sequence	259832-259860	6	0.793
NC_008312_3	3.40|615091|29|NC_008312|CRT	615091-615119	29	NZ_CP021767	Ralstonia solanacearum strain RS 489 plasmid unnamed, complete sequence	462924-462952	6	0.793
NC_008312_3	3.40|615091|29|NC_008312|CRT	615091-615119	29	NZ_CP012688	Ralstonia solanacearum strain UY031 plasmid unnamed, complete sequence	462861-462889	6	0.793
NC_008312_3	3.40|615091|29|NC_008312|CRT	615091-615119	29	NC_017575	Ralstonia solanacearum Po82 megaplasmid, complete sequence	259654-259682	6	0.793
NC_008312_3	3.40|615091|29|NC_008312|CRT	615091-615119	29	NZ_CP026308	Ralstonia solanacearum strain IBSBF 2571 plasmid unnamed, complete sequence	259641-259669	6	0.793
NC_008312_3	3.40|615091|29|NC_008312|CRT	615091-615119	29	NZ_CP021765	Ralstonia pseudosolanacearum strain CRMRs218 plasmid unnamed, complete sequence	299777-299805	6	0.793
NC_008312_3	3.40|615091|29|NC_008312|CRT	615091-615119	29	CP047139	Ralstonia solanacearum strain CFBP 8695 plasmid unnamed, complete sequence	463052-463080	6	0.793
NC_008312_3	3.40|615091|29|NC_008312|CRT	615091-615119	29	CP047137	Ralstonia solanacearum strain CFBP 8697 plasmid unnamed, complete sequence	440108-440136	6	0.793
NC_008312_3	3.40|615091|29|NC_008312|CRT	615091-615119	29	NZ_CP033220	Parasedimentitalea marina strain W43 plasmid pW43A, complete sequence	41156-41184	6	0.793
NC_008312_3	3.40|615091|29|NC_008312|CRT	615091-615119	29	NZ_CP033220	Parasedimentitalea marina strain W43 plasmid pW43A, complete sequence	122866-122894	6	0.793
NC_008312_3	3.40|615091|29|NC_008312|CRT	615091-615119	29	NC_009128	Corynebacterium sp. L2-79-05 plasmid pLEW279a, complete sequence	16480-16508	6	0.793
NC_008312_3	3.40|615091|29|NC_008312|CRT	615091-615119	29	NZ_CP004352	Corynebacterium casei LMG S-19264 plasmid pCASE2, complete sequence	6920-6948	6	0.793
NC_008312_3	3.45|615433|29|NC_008312|CRT	615433-615461	29	NC_007501	Lactobacillus phage Lc-Nu, complete genome	16339-16367	6	0.793
NC_008312_3	3.45|615433|29|NC_008312|CRT	615433-615461	29	AY131267	Bacteriophage Lc-Nu, complete genome	16339-16367	6	0.793
NC_008312_3	3.45|615433|29|NC_008312|CRT	615433-615461	29	NZ_CP022775	Ralstonia solanacearum strain T12 plasmid unnamed, complete sequence	242920-242948	6	0.793
NC_008312_3	3.45|615433|29|NC_008312|CRT	615433-615461	29	NC_014310	Ralstonia solanacearum PSI07 plasmid mpPSI07, complete sequence	236915-236943	6	0.793
NC_008312_3	3.45|615433|29|NC_008312|CRT	615433-615461	29	NZ_CP022762	Ralstonia solanacearum strain T95 plasmid unnamed, complete sequence	247061-247089	6	0.793
NC_008312_3	3.45|615433|29|NC_008312|CRT	615433-615461	29	NZ_CP023017	Ralstonia solanacearum strain SL3022 plasmid unnamed, complete sequence	230475-230503	6	0.793
NC_008312_3	3.45|615433|29|NC_008312|CRT	615433-615461	29	NZ_CP014703	Ralstonia solanacearum strain KACC 10722 plasmid, complete sequence	247061-247089	6	0.793
NC_008312_3	3.45|615433|29|NC_008312|CRT	615433-615461	29	NZ_CP022760	Ralstonia solanacearum strain T98 plasmid unnamed, complete sequence	240783-240811	6	0.793
NC_008312_3	3.45|615433|29|NC_008312|CRT	615433-615461	29	NZ_CP022789	Ralstonia solanacearum strain SL3175 plasmid unnamed, complete sequence	240772-240800	6	0.793
NC_008312_3	3.45|615433|29|NC_008312|CRT	615433-615461	29	NZ_CP022771	Ralstonia solanacearum strain T51 plasmid unnamed, complete sequence	247066-247094	6	0.793
NC_008312_3	3.45|615433|29|NC_008312|CRT	615433-615461	29	NZ_CP022777	Ralstonia solanacearum strain T11 plasmid unnamed, complete sequence	247088-247116	6	0.793
NC_008312_3	3.45|615433|29|NC_008312|CRT	615433-615461	29	NZ_CP022799	Ralstonia solanacearum strain SL2064 plasmid unnamed, complete sequence	247060-247088	6	0.793
NC_008312_3	3.45|615433|29|NC_008312|CRT	615433-615461	29	NZ_CP022764	Ralstonia solanacearum strain T82 plasmid unnamed, complete sequence	242941-242969	6	0.793
NC_008312_3	3.45|615433|29|NC_008312|CRT	615433-615461	29	NZ_CP022797	Ralstonia solanacearum strain SL2312 plasmid unnamed, complete sequence	242939-242967	6	0.793
NC_008312_3	3.45|615433|29|NC_008312|CRT	615433-615461	29	NZ_CP022758	Ralstonia solanacearum strain T101 plasmid unnamed, complete sequence	242935-242963	6	0.793
NC_008312_3	3.45|615433|29|NC_008312|CRT	615433-615461	29	NC_012654	Clostridium botulinum Ba4 str. 657 plasmid pCLJ, complete sequence	30599-30627	6	0.793
NC_008312_3	3.45|615433|29|NC_008312|CRT	615433-615461	29	NZ_CP034811	Paracoccus sp. Arc7-R13 plasmid unnamed1, complete sequence	147811-147839	6	0.793
NC_008312_3	3.45|615433|29|NC_008312|CRT	615433-615461	29	NC_028835	Lactobacillus phage CL2, complete genome	17509-17537	6	0.793
NC_008312_3	3.45|615433|29|NC_008312|CRT	615433-615461	29	KR905066	Lactobacillus phage CL1, complete genome	16494-16522	6	0.793
NC_008312_3	3.45|615433|29|NC_008312|CRT	615433-615461	29	NC_028911	Lactobacillus phage iLp1308, complete genome	16202-16230	6	0.793
NC_008312_3	3.45|615433|29|NC_008312|CRT	615433-615461	29	NZ_CP033220	Parasedimentitalea marina strain W43 plasmid pW43A, complete sequence	41156-41184	6	0.793
NC_008312_3	3.45|615433|29|NC_008312|CRT	615433-615461	29	NZ_CP033220	Parasedimentitalea marina strain W43 plasmid pW43A, complete sequence	122866-122894	6	0.793
NC_008312_3	3.45|615433|29|NC_008312|CRT	615433-615461	29	NZ_CP006909	Clostridium botulinum CDC_1436 plasmid pCBG, complete sequence	211066-211094	6	0.793
NC_008312_3	3.45|615433|29|NC_008312|CRT	615433-615461	29	NZ_CP031095	Clostridium botulinum strain CFSAN034200 plasmid p1_CDC51232, complete sequence	81534-81562	6	0.793
NC_008312_4	4.3|617317|29|NC_008312|CRT	617317-617345	29	NZ_CP033220	Parasedimentitalea marina strain W43 plasmid pW43A, complete sequence	41156-41184	6	0.793
NC_008312_4	4.3|617317|29|NC_008312|CRT	617317-617345	29	NZ_CP033220	Parasedimentitalea marina strain W43 plasmid pW43A, complete sequence	122866-122894	6	0.793
NC_008312_4	4.3|617317|29|NC_008312|CRT	617317-617345	29	NZ_CP006909	Clostridium botulinum CDC_1436 plasmid pCBG, complete sequence	211066-211094	6	0.793
NC_008312_4	4.3|617317|29|NC_008312|CRT	617317-617345	29	NZ_CP031095	Clostridium botulinum strain CFSAN034200 plasmid p1_CDC51232, complete sequence	81534-81562	6	0.793
NC_008312_4	4.3|617317|29|NC_008312|CRT	617317-617345	29	NC_009128	Corynebacterium sp. L2-79-05 plasmid pLEW279a, complete sequence	16480-16508	6	0.793
NC_008312_4	4.3|617317|29|NC_008312|CRT	617317-617345	29	NZ_CP004352	Corynebacterium casei LMG S-19264 plasmid pCASE2, complete sequence	6920-6948	6	0.793
NC_008312_4	4.3|617317|29|NC_008312|CRT	617317-617345	29	NC_012654	Clostridium botulinum Ba4 str. 657 plasmid pCLJ, complete sequence	30599-30627	6	0.793
NC_008312_4	4.3|617317|29|NC_008312|CRT	617317-617345	29	NZ_CP034811	Paracoccus sp. Arc7-R13 plasmid unnamed1, complete sequence	147811-147839	6	0.793
NC_008312_4	4.3|617317|29|NC_008312|CRT	617317-617345	29	NC_028835	Lactobacillus phage CL2, complete genome	17509-17537	6	0.793
NC_008312_4	4.3|617317|29|NC_008312|CRT	617317-617345	29	KR905066	Lactobacillus phage CL1, complete genome	16494-16522	6	0.793
NC_008312_4	4.3|617317|29|NC_008312|CRT	617317-617345	29	NC_028911	Lactobacillus phage iLp1308, complete genome	16202-16230	6	0.793
NC_008312_4	4.5|617434|29|NC_008312|CRT	617434-617462	29	NZ_CP033220	Parasedimentitalea marina strain W43 plasmid pW43A, complete sequence	41156-41184	6	0.793
NC_008312_4	4.5|617434|29|NC_008312|CRT	617434-617462	29	NZ_CP033220	Parasedimentitalea marina strain W43 plasmid pW43A, complete sequence	122866-122894	6	0.793
NC_008312_4	4.5|617434|29|NC_008312|CRT	617434-617462	29	NZ_CP006909	Clostridium botulinum CDC_1436 plasmid pCBG, complete sequence	211066-211094	6	0.793
NC_008312_4	4.5|617434|29|NC_008312|CRT	617434-617462	29	NZ_CP031095	Clostridium botulinum strain CFSAN034200 plasmid p1_CDC51232, complete sequence	81534-81562	6	0.793
NC_008312_4	4.5|617434|29|NC_008312|CRT	617434-617462	29	NC_009128	Corynebacterium sp. L2-79-05 plasmid pLEW279a, complete sequence	16480-16508	6	0.793
NC_008312_4	4.5|617434|29|NC_008312|CRT	617434-617462	29	NZ_CP004352	Corynebacterium casei LMG S-19264 plasmid pCASE2, complete sequence	6920-6948	6	0.793
NC_008312_4	4.5|617434|29|NC_008312|CRT	617434-617462	29	NC_012654	Clostridium botulinum Ba4 str. 657 plasmid pCLJ, complete sequence	30599-30627	6	0.793
NC_008312_4	4.5|617434|29|NC_008312|CRT	617434-617462	29	NZ_CP034811	Paracoccus sp. Arc7-R13 plasmid unnamed1, complete sequence	147811-147839	6	0.793
NC_008312_4	4.5|617434|29|NC_008312|CRT	617434-617462	29	NC_028835	Lactobacillus phage CL2, complete genome	17509-17537	6	0.793
NC_008312_4	4.5|617434|29|NC_008312|CRT	617434-617462	29	KR905066	Lactobacillus phage CL1, complete genome	16494-16522	6	0.793
NC_008312_4	4.5|617434|29|NC_008312|CRT	617434-617462	29	NC_028911	Lactobacillus phage iLp1308, complete genome	16202-16230	6	0.793
NC_008312_12	12.14|1607246|27|NC_008312|CRT	1607246-1607272	27	NZ_CP022182	Aeromonas salmonicida strain S68 plasmid pS68-1, complete sequence	14306-14332	6	0.778
NC_008312_12	12.14|1607246|27|NC_008312|CRT	1607246-1607272	27	NZ_CP022177	Aeromonas salmonicida strain S44 plasmid pS44-2, complete sequence	33093-33119	6	0.778
NC_008312_12	12.14|1607246|27|NC_008312|CRT	1607246-1607272	27	NZ_CP017144	Aeromonas salmonicida subsp. masoucida strain RFAS1 plasmid unnamed1, complete sequence	31757-31783	6	0.778
NC_008312_12	12.14|1607246|27|NC_008312|CRT	1607246-1607272	27	NZ_CP022171	Aeromonas salmonicida strain S121 plasmid pS121-2, complete sequence	44934-44960	6	0.778
NC_008312_17	17.1|1941253|35|NC_008312|CRISPRCasFinder	1941253-1941287	35	NC_028924	Polaribacter phage P12002L, complete genome	45508-45542	6	0.829
NC_008312_17	17.1|1941253|35|NC_008312|CRISPRCasFinder	1941253-1941287	35	NC_028763	Polaribacter phage P12002S, complete genome	46421-46455	6	0.829
NC_008312_21	21.19|2628169|26|NC_008312|CRT	2628169-2628194	26	MN693047	Marine virus AFVG_25M111, complete genome	33209-33234	6	0.769
NC_008312_21	21.19|2628169|26|NC_008312|CRT	2628169-2628194	26	MN693506	Marine virus AFVG_25M112, complete genome	32970-32995	6	0.769
NC_008312_21	21.21|2628250|26|NC_008312|CRT	2628250-2628275	26	MN693047	Marine virus AFVG_25M111, complete genome	33209-33234	6	0.769
NC_008312_21	21.21|2628250|26|NC_008312|CRT	2628250-2628275	26	MN693506	Marine virus AFVG_25M112, complete genome	32970-32995	6	0.769
NC_008312_21	21.32|2628710|26|NC_008312|CRT	2628710-2628735	26	KX119180	Helicobacter phage Pt5303G hypothetical protein and putative transcriptional regulator protein genes, complete cds	1546-1571	6	0.769
NC_008312_21	21.51|2629736|40|NC_008312|CRT	2629736-2629775	40	NZ_CP015730	Bacillus cereus strain A1 plasmid pBCA1, complete sequence	77629-77668	6	0.85
NC_008312_21	21.51|2629736|40|NC_008312|CRT	2629736-2629775	40	NZ_CP015730	Bacillus cereus strain A1 plasmid pBCA1, complete sequence	77636-77675	6	0.85
NC_008312_29	29.4|3671731|26|NC_008312|CRISPRCasFinder	3671731-3671756	26	KC465899	Pelagibacter phage HTVC008M, complete genome	47604-47629	6	0.769
NC_008312_33	33.1|4206516|31|NC_008312|CRISPRCasFinder	4206516-4206546	31	KX229736	Campylobacter phage PC5, complete genome	92711-92741	6	0.806
NC_008312_33	33.1|4206516|31|NC_008312|CRISPRCasFinder	4206516-4206546	31	NC_015464	Campylobacter phage NCTC12673, complete genome	53958-53988	6	0.806
NC_008312_33	33.1|4206516|31|NC_008312|CRISPRCasFinder	4206516-4206546	31	KX236333	Campylobacter phage PC14, complete genome	88951-88981	6	0.806
NC_008312_33	33.1|4206516|31|NC_008312|CRISPRCasFinder	4206516-4206546	31	JX569801	Campylobacter phage CP30A, complete genome	56146-56176	6	0.806
NC_008312_45	45.6|6864734|30|NC_008312|CRT	6864734-6864763	30	NZ_CP016613	Ralstonia solanacearum FJAT-91 plasmid unnamed1, complete sequence	1660070-1660099	6	0.8
NC_008312_45	45.6|6864734|30|NC_008312|CRT	6864734-6864763	30	NZ_CP027115	Gordonia alkanivorans strain YC-RL2 plasmid pYYC01, complete sequence	17585-17614	6	0.8
NC_008312_45	45.6|6864734|30|NC_008312|CRT	6864734-6864763	30	NZ_CP052069	Ralstonia solanacearum strain FJAT91.F50 plasmid Plas1, complete sequence	970845-970874	6	0.8
NC_008312_45	45.6|6864734|30|NC_008312|CRT	6864734-6864763	30	NZ_CP022581	Gordonia rubripertincta strain CWB2 plasmid pGCWB2, complete sequence	82328-82357	6	0.8
NC_008312_45	45.6|6864734|30|NC_008312|CRT	6864734-6864763	30	NZ_CP032348	Azospirillum brasilense strain MTCC4039 plasmid p4, complete sequence	539739-539768	6	0.8
NC_008312_45	45.6|6864734|30|NC_008312|CRT	6864734-6864763	30	NZ_CP013589	Rhizobium phaseoli strain N161 plasmid pRphaN161d, complete sequence	109846-109875	6	0.8
NC_008312_45	45.6|6864734|30|NC_008312|CRT	6864734-6864763	30	NZ_CP025432	Paracoccus zhejiangensis strain J6 plasmid pPZ02, complete sequence	30181-30210	6	0.8
NC_008312_45	45.6|6864734|30|NC_008312|CRT	6864734-6864763	30	NZ_CP032703	Pantoea dispersa strain DSM 32899 plasmid unnamed1, complete sequence	237567-237596	6	0.8
NC_008312_47	47.1|7278276|30|NC_008312|CRISPRCasFinder	7278276-7278305	30	NC_024355	Staphylococcus phage 6ec, complete genome	82214-82243	6	0.8
NC_008312_3	3.4|613093|29|NC_008312|CRT	613093-613121	29	KT997873	Uncultured Mediterranean phage uvDeep-CGR2-KM21-C368, complete genome	20082-20110	7	0.759
NC_008312_3	3.4|613093|29|NC_008312|CRT	613093-613121	29	NZ_KX893538	Pseudomonas fluorescens strain PC20 plasmid pG20, complete sequence	30818-30846	7	0.759
NC_008312_3	3.4|613093|29|NC_008312|CRT	613093-613121	29	NZ_CP016083	Streptomyces sp. SAT1 plasmid unnamed3, complete sequence	216044-216072	7	0.759
NC_008312_3	3.4|613093|29|NC_008312|CRT	613093-613121	29	NZ_CP028885	Borrelia turcica IST7 plasmid lp129, complete sequence	71696-71724	7	0.759
NC_008312_3	3.4|613093|29|NC_008312|CRT	613093-613121	29	NC_009128	Corynebacterium sp. L2-79-05 plasmid pLEW279a, complete sequence	16480-16508	7	0.759
NC_008312_3	3.4|613093|29|NC_008312|CRT	613093-613121	29	NZ_CP004352	Corynebacterium casei LMG S-19264 plasmid pCASE2, complete sequence	6920-6948	7	0.759
NC_008312_3	3.22|614119|29|NC_008312|CRT	614119-614147	29	NC_007501	Lactobacillus phage Lc-Nu, complete genome	16339-16367	7	0.759
NC_008312_3	3.22|614119|29|NC_008312|CRT	614119-614147	29	AY131267	Bacteriophage Lc-Nu, complete genome	16339-16367	7	0.759
NC_008312_3	3.22|614119|29|NC_008312|CRT	614119-614147	29	NZ_CP032678	Pseudomonas sp. Leaf58 plasmid pBASL58, complete sequence	797916-797944	7	0.759
NC_008312_3	3.24|614218|29|NC_008312|CRT	614218-614246	29	NC_012654	Clostridium botulinum Ba4 str. 657 plasmid pCLJ, complete sequence	30599-30627	7	0.759
NC_008312_3	3.24|614218|29|NC_008312|CRT	614218-614246	29	NZ_CP034811	Paracoccus sp. Arc7-R13 plasmid unnamed1, complete sequence	147811-147839	7	0.759
NC_008312_3	3.24|614218|29|NC_008312|CRT	614218-614246	29	NZ_CP006909	Clostridium botulinum CDC_1436 plasmid pCBG, complete sequence	211066-211094	7	0.759
NC_008312_3	3.24|614218|29|NC_008312|CRT	614218-614246	29	NZ_CP031095	Clostridium botulinum strain CFSAN034200 plasmid p1_CDC51232, complete sequence	81534-81562	7	0.759
NC_008312_3	3.24|614218|29|NC_008312|CRT	614218-614246	29	NZ_CP032678	Pseudomonas sp. Leaf58 plasmid pBASL58, complete sequence	797916-797944	7	0.759
NC_008312_3	3.24|614218|29|NC_008312|CRT	614218-614246	29	NC_009128	Corynebacterium sp. L2-79-05 plasmid pLEW279a, complete sequence	16480-16508	7	0.759
NC_008312_3	3.24|614218|29|NC_008312|CRT	614218-614246	29	NZ_CP004352	Corynebacterium casei LMG S-19264 plasmid pCASE2, complete sequence	6920-6948	7	0.759
NC_008312_3	3.29|614479|29|NC_008312|CRT	614479-614507	29	NZ_CP022775	Ralstonia solanacearum strain T12 plasmid unnamed, complete sequence	242920-242948	7	0.759
NC_008312_3	3.29|614479|29|NC_008312|CRT	614479-614507	29	NC_014310	Ralstonia solanacearum PSI07 plasmid mpPSI07, complete sequence	236915-236943	7	0.759
NC_008312_3	3.29|614479|29|NC_008312|CRT	614479-614507	29	NZ_CP022762	Ralstonia solanacearum strain T95 plasmid unnamed, complete sequence	247061-247089	7	0.759
NC_008312_3	3.29|614479|29|NC_008312|CRT	614479-614507	29	NZ_CP023017	Ralstonia solanacearum strain SL3022 plasmid unnamed, complete sequence	230475-230503	7	0.759
NC_008312_3	3.29|614479|29|NC_008312|CRT	614479-614507	29	NZ_CP014703	Ralstonia solanacearum strain KACC 10722 plasmid, complete sequence	247061-247089	7	0.759
NC_008312_3	3.29|614479|29|NC_008312|CRT	614479-614507	29	NZ_CP022760	Ralstonia solanacearum strain T98 plasmid unnamed, complete sequence	240783-240811	7	0.759
NC_008312_3	3.29|614479|29|NC_008312|CRT	614479-614507	29	NZ_CP022789	Ralstonia solanacearum strain SL3175 plasmid unnamed, complete sequence	240772-240800	7	0.759
NC_008312_3	3.29|614479|29|NC_008312|CRT	614479-614507	29	NZ_CP022771	Ralstonia solanacearum strain T51 plasmid unnamed, complete sequence	247066-247094	7	0.759
NC_008312_3	3.29|614479|29|NC_008312|CRT	614479-614507	29	NZ_CP022777	Ralstonia solanacearum strain T11 plasmid unnamed, complete sequence	247088-247116	7	0.759
NC_008312_3	3.29|614479|29|NC_008312|CRT	614479-614507	29	NZ_CP022799	Ralstonia solanacearum strain SL2064 plasmid unnamed, complete sequence	247060-247088	7	0.759
NC_008312_3	3.29|614479|29|NC_008312|CRT	614479-614507	29	NZ_CP022764	Ralstonia solanacearum strain T82 plasmid unnamed, complete sequence	242941-242969	7	0.759
NC_008312_3	3.29|614479|29|NC_008312|CRT	614479-614507	29	NZ_CP022797	Ralstonia solanacearum strain SL2312 plasmid unnamed, complete sequence	242939-242967	7	0.759
NC_008312_3	3.29|614479|29|NC_008312|CRT	614479-614507	29	NZ_CP022758	Ralstonia solanacearum strain T101 plasmid unnamed, complete sequence	242935-242963	7	0.759
NC_008312_3	3.29|614479|29|NC_008312|CRT	614479-614507	29	NZ_CP049158	Caballeronia sp. SBC1 plasmid pSBC1_2, complete sequence	634592-634620	7	0.759
NC_008312_3	3.29|614479|29|NC_008312|CRT	614479-614507	29	NZ_CP049318	Caballeronia sp. SBC2 plasmid pSBC2-2, complete sequence	633803-633831	7	0.759
NC_008312_3	3.29|614479|29|NC_008312|CRT	614479-614507	29	NC_012654	Clostridium botulinum Ba4 str. 657 plasmid pCLJ, complete sequence	30599-30627	7	0.759
NC_008312_3	3.29|614479|29|NC_008312|CRT	614479-614507	29	NZ_CP034811	Paracoccus sp. Arc7-R13 plasmid unnamed1, complete sequence	147811-147839	7	0.759
NC_008312_3	3.29|614479|29|NC_008312|CRT	614479-614507	29	NZ_CP006909	Clostridium botulinum CDC_1436 plasmid pCBG, complete sequence	211066-211094	7	0.759
NC_008312_3	3.29|614479|29|NC_008312|CRT	614479-614507	29	NZ_CP031095	Clostridium botulinum strain CFSAN034200 plasmid p1_CDC51232, complete sequence	81534-81562	7	0.759
NC_008312_3	3.29|614479|29|NC_008312|CRT	614479-614507	29	NZ_CP032678	Pseudomonas sp. Leaf58 plasmid pBASL58, complete sequence	797916-797944	7	0.759
NC_008312_3	3.33|614713|29|NC_008312|CRT	614713-614741	29	NC_012654	Clostridium botulinum Ba4 str. 657 plasmid pCLJ, complete sequence	30599-30627	7	0.759
NC_008312_3	3.33|614713|29|NC_008312|CRT	614713-614741	29	NZ_CP034811	Paracoccus sp. Arc7-R13 plasmid unnamed1, complete sequence	147811-147839	7	0.759
NC_008312_3	3.33|614713|29|NC_008312|CRT	614713-614741	29	NZ_CP006909	Clostridium botulinum CDC_1436 plasmid pCBG, complete sequence	211066-211094	7	0.759
NC_008312_3	3.33|614713|29|NC_008312|CRT	614713-614741	29	NZ_CP031095	Clostridium botulinum strain CFSAN034200 plasmid p1_CDC51232, complete sequence	81534-81562	7	0.759
NC_008312_3	3.33|614713|29|NC_008312|CRT	614713-614741	29	NZ_CP032678	Pseudomonas sp. Leaf58 plasmid pBASL58, complete sequence	797916-797944	7	0.759
NC_008312_3	3.33|614713|29|NC_008312|CRT	614713-614741	29	NC_009128	Corynebacterium sp. L2-79-05 plasmid pLEW279a, complete sequence	16480-16508	7	0.759
NC_008312_3	3.33|614713|29|NC_008312|CRT	614713-614741	29	NZ_CP004352	Corynebacterium casei LMG S-19264 plasmid pCASE2, complete sequence	6920-6948	7	0.759
NC_008312_3	3.35|614830|29|NC_008312|CRT	614830-614858	29	NZ_CP049158	Caballeronia sp. SBC1 plasmid pSBC1_2, complete sequence	634592-634620	7	0.759
NC_008312_3	3.35|614830|29|NC_008312|CRT	614830-614858	29	NZ_CP049318	Caballeronia sp. SBC2 plasmid pSBC2-2, complete sequence	633803-633831	7	0.759
NC_008312_3	3.35|614830|29|NC_008312|CRT	614830-614858	29	NZ_CP032678	Pseudomonas sp. Leaf58 plasmid pBASL58, complete sequence	797916-797944	7	0.759
NC_008312_3	3.40|615091|29|NC_008312|CRT	615091-615119	29	NZ_CP022775	Ralstonia solanacearum strain T12 plasmid unnamed, complete sequence	242920-242948	7	0.759
NC_008312_3	3.40|615091|29|NC_008312|CRT	615091-615119	29	NC_014310	Ralstonia solanacearum PSI07 plasmid mpPSI07, complete sequence	236915-236943	7	0.759
NC_008312_3	3.40|615091|29|NC_008312|CRT	615091-615119	29	NZ_CP022762	Ralstonia solanacearum strain T95 plasmid unnamed, complete sequence	247061-247089	7	0.759
NC_008312_3	3.40|615091|29|NC_008312|CRT	615091-615119	29	NZ_CP023017	Ralstonia solanacearum strain SL3022 plasmid unnamed, complete sequence	230475-230503	7	0.759
NC_008312_3	3.40|615091|29|NC_008312|CRT	615091-615119	29	NZ_CP014703	Ralstonia solanacearum strain KACC 10722 plasmid, complete sequence	247061-247089	7	0.759
NC_008312_3	3.40|615091|29|NC_008312|CRT	615091-615119	29	NZ_CP022760	Ralstonia solanacearum strain T98 plasmid unnamed, complete sequence	240783-240811	7	0.759
NC_008312_3	3.40|615091|29|NC_008312|CRT	615091-615119	29	NZ_CP022789	Ralstonia solanacearum strain SL3175 plasmid unnamed, complete sequence	240772-240800	7	0.759
NC_008312_3	3.40|615091|29|NC_008312|CRT	615091-615119	29	NZ_CP022771	Ralstonia solanacearum strain T51 plasmid unnamed, complete sequence	247066-247094	7	0.759
NC_008312_3	3.40|615091|29|NC_008312|CRT	615091-615119	29	NZ_CP022777	Ralstonia solanacearum strain T11 plasmid unnamed, complete sequence	247088-247116	7	0.759
NC_008312_3	3.40|615091|29|NC_008312|CRT	615091-615119	29	NZ_CP022799	Ralstonia solanacearum strain SL2064 plasmid unnamed, complete sequence	247060-247088	7	0.759
NC_008312_3	3.40|615091|29|NC_008312|CRT	615091-615119	29	NZ_CP022764	Ralstonia solanacearum strain T82 plasmid unnamed, complete sequence	242941-242969	7	0.759
NC_008312_3	3.40|615091|29|NC_008312|CRT	615091-615119	29	NZ_CP022797	Ralstonia solanacearum strain SL2312 plasmid unnamed, complete sequence	242939-242967	7	0.759
NC_008312_3	3.40|615091|29|NC_008312|CRT	615091-615119	29	NZ_CP022758	Ralstonia solanacearum strain T101 plasmid unnamed, complete sequence	242935-242963	7	0.759
NC_008312_3	3.40|615091|29|NC_008312|CRT	615091-615119	29	NZ_CP049158	Caballeronia sp. SBC1 plasmid pSBC1_2, complete sequence	634592-634620	7	0.759
NC_008312_3	3.40|615091|29|NC_008312|CRT	615091-615119	29	NZ_CP049318	Caballeronia sp. SBC2 plasmid pSBC2-2, complete sequence	633803-633831	7	0.759
NC_008312_3	3.40|615091|29|NC_008312|CRT	615091-615119	29	NC_012654	Clostridium botulinum Ba4 str. 657 plasmid pCLJ, complete sequence	30599-30627	7	0.759
NC_008312_3	3.40|615091|29|NC_008312|CRT	615091-615119	29	NZ_CP034811	Paracoccus sp. Arc7-R13 plasmid unnamed1, complete sequence	147811-147839	7	0.759
NC_008312_3	3.40|615091|29|NC_008312|CRT	615091-615119	29	NZ_CP006909	Clostridium botulinum CDC_1436 plasmid pCBG, complete sequence	211066-211094	7	0.759
NC_008312_3	3.40|615091|29|NC_008312|CRT	615091-615119	29	NZ_CP031095	Clostridium botulinum strain CFSAN034200 plasmid p1_CDC51232, complete sequence	81534-81562	7	0.759
NC_008312_3	3.40|615091|29|NC_008312|CRT	615091-615119	29	NZ_CP032678	Pseudomonas sp. Leaf58 plasmid pBASL58, complete sequence	797916-797944	7	0.759
NC_008312_3	3.45|615433|29|NC_008312|CRT	615433-615461	29	NZ_CP049158	Caballeronia sp. SBC1 plasmid pSBC1_2, complete sequence	634592-634620	7	0.759
NC_008312_3	3.45|615433|29|NC_008312|CRT	615433-615461	29	NZ_CP049318	Caballeronia sp. SBC2 plasmid pSBC2-2, complete sequence	633803-633831	7	0.759
NC_008312_3	3.45|615433|29|NC_008312|CRT	615433-615461	29	NZ_CP032678	Pseudomonas sp. Leaf58 plasmid pBASL58, complete sequence	797916-797944	7	0.759
NC_008312_3	3.63|616822|38|NC_008312|CRT	616822-616859	38	NC_010181	Bacillus mycoides KBAB4 plasmid pBWB402, complete sequence	27710-27747	7	0.816
NC_008312_3	3.63|616822|38|NC_008312|CRT	616822-616859	38	MN693968	Marine virus AFVG_250M909, complete genome	17535-17572	7	0.816
NC_008312_4	4.2|617254|29|NC_008312|CRT	617254-617282	29	NZ_CP016083	Streptomyces sp. SAT1 plasmid unnamed3, complete sequence	783466-783494	7	0.759
NC_008312_4	4.2|617254|29|NC_008312|CRT	617254-617282	29	MH171096	Streptomyces phage Eddasa, complete genome	17592-17620	7	0.759
NC_008312_4	4.2|617254|29|NC_008312|CRT	617254-617282	29	MN096381	Streptomyces phage Rusticus, complete genome	17592-17620	7	0.759
NC_008312_4	4.2|617254|29|NC_008312|CRT	617254-617282	29	MF541404	Streptomyces phage BryanRecycles, complete genome	17592-17620	7	0.759
NC_008312_4	4.2|617254|29|NC_008312|CRT	617254-617282	29	NC_028976	Streptomyces phage Izzy, complete genome	17639-17667	7	0.759
NC_008312_4	4.2|617254|29|NC_008312|CRT	617254-617282	29	MF541408	Streptomyces phage Jash, complete genome	17592-17620	7	0.759
NC_008312_4	4.2|617254|29|NC_008312|CRT	617254-617282	29	MF541409	Streptomyces phage Oliynyk, complete genome	17592-17620	7	0.759
NC_008312_4	4.2|617254|29|NC_008312|CRT	617254-617282	29	NZ_CP029835	Azospirillum ramasamyi strain M2T2B2 plasmid unnamed5, complete sequence	59231-59259	7	0.759
NC_008312_4	4.3|617317|29|NC_008312|CRT	617317-617345	29	NC_007501	Lactobacillus phage Lc-Nu, complete genome	16339-16367	7	0.759
NC_008312_4	4.3|617317|29|NC_008312|CRT	617317-617345	29	AY131267	Bacteriophage Lc-Nu, complete genome	16339-16367	7	0.759
NC_008312_4	4.3|617317|29|NC_008312|CRT	617317-617345	29	NZ_CP032678	Pseudomonas sp. Leaf58 plasmid pBASL58, complete sequence	797916-797944	7	0.759
NC_008312_4	4.5|617434|29|NC_008312|CRT	617434-617462	29	NC_007501	Lactobacillus phage Lc-Nu, complete genome	16339-16367	7	0.759
NC_008312_4	4.5|617434|29|NC_008312|CRT	617434-617462	29	AY131267	Bacteriophage Lc-Nu, complete genome	16339-16367	7	0.759
NC_008312_4	4.5|617434|29|NC_008312|CRT	617434-617462	29	NZ_CP032678	Pseudomonas sp. Leaf58 plasmid pBASL58, complete sequence	797916-797944	7	0.759
NC_008312_6	6.1|904049|29|NC_008312|CRISPRCasFinder	904049-904077	29	MW147367	Synechococcus phage S-H9-2, complete genome	147606-147634	7	0.759
NC_008312_7	7.1|1110187|30|NC_008312|CRISPRCasFinder	1110187-1110216	30	NZ_CP032095	Vibrio alfacsensis strain CAIM 1831 plasmid pVa1, complete sequence	124053-124082	7	0.767
NC_008312_7	7.1|1110187|30|NC_008312|CRISPRCasFinder	1110187-1110216	30	NZ_CP018030	Alteromonas mediterranea strain RG65 plasmid MRG65-300, complete sequence	146883-146912	7	0.767
NC_008312_12	12.14|1607246|27|NC_008312|CRT	1607246-1607272	27	MH617645	Inoviridae sp. isolate ctcb11, complete genome	4178-4204	7	0.741
NC_008312_21	21.37|2628935|26|NC_008312|CRT	2628935-2628960	26	NZ_CP016746	Lactococcus lactis subsp. cremoris strain JM1 plasmid pMPJM1, complete sequence	61414-61439	7	0.731
NC_008312_21	21.63|2630374|26|NC_008312|CRT	2630374-2630399	26	NZ_CP016746	Lactococcus lactis subsp. cremoris strain JM1 plasmid pMPJM1, complete sequence	61414-61439	7	0.731
NC_008312_21	21.80|2631158|26|NC_008312|CRT	2631158-2631183	26	NZ_CP016746	Lactococcus lactis subsp. cremoris strain JM1 plasmid pMPJM1, complete sequence	61414-61439	7	0.731
NC_008312_45	45.6|6864734|30|NC_008312|CRT	6864734-6864763	30	NZ_CP007129	Gemmatirosa kalamazoonesis strain KBS708 plasmid 1, complete sequence	1093179-1093208	7	0.767
NC_008312_45	45.6|6864734|30|NC_008312|CRT	6864734-6864763	30	CP031732	Stenotrophomonas rhizophila strain GA1 plasmid unnamed3, complete sequence	86859-86888	7	0.767
NC_008312_45	45.6|6864734|30|NC_008312|CRT	6864734-6864763	30	NZ_CP054616	Azospirillum oryzae strain KACC 14407 plasmid unnamed2, complete sequence	625063-625092	7	0.767
NC_008312_45	45.6|6864734|30|NC_008312|CRT	6864734-6864763	30	NZ_CP030263	Ensifer adhaerens strain Corn53 plasmid AA, complete sequence	1074302-1074331	7	0.767
NC_008312_47	47.1|7278276|30|NC_008312|CRISPRCasFinder	7278276-7278305	30	NZ_FO818639	Xenorhabdus bovienii strain CS03 plasmid XBC_p, complete sequence	6320-6349	7	0.767
NC_008312_47	47.1|7278276|30|NC_008312|CRISPRCasFinder	7278276-7278305	30	KF929199	Staphylococcus phage vB_SepS_SEP9, complete genome	74978-75007	7	0.767
NC_008312_3	3.4|613093|29|NC_008312|CRT	613093-613121	29	NZ_CP012183	Pseudonocardia sp. EC080610-09 plasmid pBCI2-2, complete sequence	83222-83250	8	0.724
NC_008312_3	3.4|613093|29|NC_008312|CRT	613093-613121	29	KU594605	Cyanophage S-RIM50 isolate RW_29_0704, complete genome	88894-88922	8	0.724
NC_008312_3	3.4|613093|29|NC_008312|CRT	613093-613121	29	NZ_CP028885	Borrelia turcica IST7 plasmid lp129, complete sequence	71783-71811	8	0.724
NC_008312_3	3.4|613093|29|NC_008312|CRT	613093-613121	29	NZ_CP028885	Borrelia turcica IST7 plasmid lp129, complete sequence	71816-71844	8	0.724
NC_008312_3	3.4|613093|29|NC_008312|CRT	613093-613121	29	NZ_CP028885	Borrelia turcica IST7 plasmid lp129, complete sequence	71867-71895	8	0.724
NC_008312_3	3.4|613093|29|NC_008312|CRT	613093-613121	29	NZ_CP028885	Borrelia turcica IST7 plasmid lp129, complete sequence	71900-71928	8	0.724
NC_008312_3	3.4|613093|29|NC_008312|CRT	613093-613121	29	NZ_CP028885	Borrelia turcica IST7 plasmid lp129, complete sequence	71933-71961	8	0.724
NC_008312_3	3.22|614119|29|NC_008312|CRT	614119-614147	29	NZ_CP049158	Caballeronia sp. SBC1 plasmid pSBC1_2, complete sequence	634592-634620	8	0.724
NC_008312_3	3.22|614119|29|NC_008312|CRT	614119-614147	29	NZ_CP049318	Caballeronia sp. SBC2 plasmid pSBC2-2, complete sequence	633803-633831	8	0.724
NC_008312_3	3.24|614218|29|NC_008312|CRT	614218-614246	29	NZ_CP049158	Caballeronia sp. SBC1 plasmid pSBC1_2, complete sequence	634592-634620	8	0.724
NC_008312_3	3.24|614218|29|NC_008312|CRT	614218-614246	29	NZ_CP049318	Caballeronia sp. SBC2 plasmid pSBC2-2, complete sequence	633803-633831	8	0.724
NC_008312_3	3.33|614713|29|NC_008312|CRT	614713-614741	29	NZ_CP049158	Caballeronia sp. SBC1 plasmid pSBC1_2, complete sequence	634592-634620	8	0.724
NC_008312_3	3.33|614713|29|NC_008312|CRT	614713-614741	29	NZ_CP049318	Caballeronia sp. SBC2 plasmid pSBC2-2, complete sequence	633803-633831	8	0.724
NC_008312_4	4.3|617317|29|NC_008312|CRT	617317-617345	29	NZ_CP049158	Caballeronia sp. SBC1 plasmid pSBC1_2, complete sequence	634592-634620	8	0.724
NC_008312_4	4.3|617317|29|NC_008312|CRT	617317-617345	29	NZ_CP049318	Caballeronia sp. SBC2 plasmid pSBC2-2, complete sequence	633803-633831	8	0.724
NC_008312_4	4.5|617434|29|NC_008312|CRT	617434-617462	29	NZ_CP049158	Caballeronia sp. SBC1 plasmid pSBC1_2, complete sequence	634592-634620	8	0.724
NC_008312_4	4.5|617434|29|NC_008312|CRT	617434-617462	29	NZ_CP049318	Caballeronia sp. SBC2 plasmid pSBC2-2, complete sequence	633803-633831	8	0.724
NC_008312_12	12.4|1606574|49|NC_008312|CRT	1606574-1606622	49	AP017993	Planktothrix agardhii NIES-204 plasmid plasmid2 DNA, complete sequence	78629-78677	8	0.837
NC_008312_12	12.6|1606695|47|NC_008312|CRT	1606695-1606741	47	AP017993	Planktothrix agardhii NIES-204 plasmid plasmid2 DNA, complete sequence	78629-78675	8	0.83
NC_008312_17	17.1|1941253|35|NC_008312|CRISPRCasFinder	1941253-1941287	35	NZ_CP038863	Campylobacter jejuni strain SCJK2 plasmid unnamed1, complete sequence	51278-51312	8	0.771
NC_008312_23	23.1|2941370|38|NC_008312|CRT	2941370-2941407	38	NC_015511	Haliscomenobacter hydrossis DSM 1100 plasmid pHALHY01, complete sequence	2180-2217	8	0.789
NC_008312_45	45.6|6864734|30|NC_008312|CRT	6864734-6864763	30	NZ_CP054616	Azospirillum oryzae strain KACC 14407 plasmid unnamed2, complete sequence	625051-625080	8	0.733
NC_008312_45	45.6|6864734|30|NC_008312|CRT	6864734-6864763	30	NZ_CP039899	Agrobacterium tumefaciens strain CFBP5877 plasmid pAtCFBP5877a, complete sequence	132350-132379	8	0.733
NC_008312_45	45.6|6864734|30|NC_008312|CRT	6864734-6864763	30	NC_013855	Azospirillum sp. B510 plasmid pAB510a, complete sequence	1018358-1018387	8	0.733
NC_008312_45	45.6|6864734|30|NC_008312|CRT	6864734-6864763	30	NC_013855	Azospirillum sp. B510 plasmid pAB510a, complete sequence	1021918-1021947	8	0.733
NC_008312_45	45.6|6864734|30|NC_008312|CRT	6864734-6864763	30	NZ_CP030074	Streptomyces sp. ZFG47 plasmid unnamed1, complete sequence	626006-626035	8	0.733
NC_008312_45	45.6|6864734|30|NC_008312|CRT	6864734-6864763	30	NZ_CP023408	Streptomyces fungicidicus strain TXX3120 plasmid p1, complete sequence	576587-576616	8	0.733
NC_008312_45	45.6|6864734|30|NC_008312|CRT	6864734-6864763	30	NZ_CP039890	Agrobacterium tumefaciens strain CFBP5499 plasmid pAtCFBP5499a, complete sequence	132350-132379	8	0.733
NC_008312_45	45.6|6864734|30|NC_008312|CRT	6864734-6864763	30	KJ538722	Mycobacterium phage HH92, complete genome	2701-2730	8	0.733
NC_008312_45	45.6|6864734|30|NC_008312|CRT	6864734-6864763	30	KT222940	Mycobacterium phage Kinbote, complete genome	2701-2730	8	0.733
NC_008312_45	45.6|6864734|30|NC_008312|CRT	6864734-6864763	30	MH727549	Mycobacterium phage Gancho, complete genome	2407-2436	8	0.733
NC_008312_45	45.6|6864734|30|NC_008312|CRT	6864734-6864763	30	MK919482	Mycobacterium phage DeepSoil15, complete genome	2701-2730	8	0.733
NC_008312_45	45.6|6864734|30|NC_008312|CRT	6864734-6864763	30	MT657330	Mycobacterium phage Webster2, complete genome	2701-2730	8	0.733
NC_008312_45	45.6|6864734|30|NC_008312|CRT	6864734-6864763	30	MF919517	Mycobacterium phage LilHazelnut, complete genome	2701-2730	8	0.733
NC_008312_45	45.6|6864734|30|NC_008312|CRT	6864734-6864763	30	EU203571	Mycobacterium phage Giles, complete genome	2701-2730	8	0.733
NC_008312_45	45.6|6864734|30|NC_008312|CRT	6864734-6864763	30	MK494095	Mycobacterium phage Daegal, complete genome	2980-3009	8	0.733
NC_008312_45	45.6|6864734|30|NC_008312|CRT	6864734-6864763	30	MT818421	Mycobacterium phage Luke, complete genome	2701-2730	8	0.733
NC_008312_45	45.6|6864734|30|NC_008312|CRT	6864734-6864763	30	MH697577	Mycobacterium phage Amochick, complete genome	2701-2730	8	0.733
NC_008312_45	45.6|6864734|30|NC_008312|CRT	6864734-6864763	30	MT684594	Mycobacterium phage Hadrien, complete genome	2701-2730	8	0.733
NC_008312_45	45.6|6864734|30|NC_008312|CRT	6864734-6864763	30	MT114159	Mycobacterium phage Ein37, complete genome	2701-2730	8	0.733
NC_008312_45	45.6|6864734|30|NC_008312|CRT	6864734-6864763	30	KT246485	Mycobacterium phage OBUpride, complete genome	2701-2730	8	0.733
NC_008312_45	45.6|6864734|30|NC_008312|CRT	6864734-6864763	30	KT454972	Mycobacterium phage Evanesce, complete genome	2701-2730	8	0.733
NC_008312_47	47.1|7278276|30|NC_008312|CRISPRCasFinder	7278276-7278305	30	NZ_CP029455	Bacillus cereus strain FORC087 plasmid pFORC087.1, complete sequence	387822-387851	8	0.733
NC_008312_3	3.4|613093|29|NC_008312|CRT	613093-613121	29	NZ_CP011515	Mitsuaria sp. 7 plasmid, complete sequence	84800-84828	9	0.69
NC_008312_21	21.51|2629736|40|NC_008312|CRT	2629736-2629775	40	NZ_CP015730	Bacillus cereus strain A1 plasmid pBCA1, complete sequence	77643-77682	9	0.775
NC_008312_21	21.51|2629736|40|NC_008312|CRT	2629736-2629775	40	NZ_CP015730	Bacillus cereus strain A1 plasmid pBCA1, complete sequence	77622-77661	9	0.775
NC_008312_23	23.1|2941370|38|NC_008312|CRT	2941370-2941407	38	NZ_CP015730	Bacillus cereus strain A1 plasmid pBCA1, complete sequence	77642-77679	9	0.763
NC_008312_33	33.1|4206516|31|NC_008312|CRISPRCasFinder	4206516-4206546	31	NC_003905	Proteus vulgaris plasmid Rts1 DNA, complete sequence	26661-26691	9	0.71
NC_008312_44	44.1|6722439|35|NC_008312|CRISPRCasFinder	6722439-6722473	35	NZ_CP047427	Spiroplasma citri strain C189 plasmid pScpC189-1, complete sequence	620-654	9	0.743
NC_008312_44	44.1|6722439|35|NC_008312|CRISPRCasFinder	6722439-6722473	35	NZ_CP047431	Spiroplasma citri strain BLH-13 plasmid pSciBLH13-3, complete sequence	13868-13902	9	0.743
NC_008312_44	44.1|6722439|35|NC_008312|CRISPRCasFinder	6722439-6722473	35	NZ_CP046369	Spiroplasma citri strain BR12 plasmid pScpBR12-1, complete sequence	12349-12383	9	0.743
NC_008312_44	44.1|6722439|35|NC_008312|CRISPRCasFinder	6722439-6722473	35	NZ_CP042474	Spiroplasma citri strain CC-2 plasmid pScpCC2-2, complete sequence	33542-33576	9	0.743
NC_008312_44	44.1|6722439|35|NC_008312|CRISPRCasFinder	6722439-6722473	35	MT074137	Bacteroides phage DAC16, complete genome	45846-45880	9	0.743
NC_008312_44	44.1|6722439|35|NC_008312|CRISPRCasFinder	6722439-6722473	35	MT074142	Bacteroides phage DAC23, complete genome	45942-45976	9	0.743
NC_008312_44	44.1|6722439|35|NC_008312|CRISPRCasFinder	6722439-6722473	35	MT074141	Bacteroides phage DAC22, complete genome	4945-4979	9	0.743
NC_008312_44	44.1|6722439|35|NC_008312|CRISPRCasFinder	6722439-6722473	35	MT074141	Bacteroides phage DAC22, complete genome	48251-48285	9	0.743
NC_008312_44	44.1|6722439|35|NC_008312|CRISPRCasFinder	6722439-6722473	35	MT074146	Bacteroides phage SJC03, complete genome	40883-40917	9	0.743
NC_008312_44	44.1|6722439|35|NC_008312|CRISPRCasFinder	6722439-6722473	35	MT074139	Bacteroides phage DAC19, complete genome	4945-4979	9	0.743
NC_008312_44	44.1|6722439|35|NC_008312|CRISPRCasFinder	6722439-6722473	35	MT074140	Bacteroides phage DAC20, complete genome	4945-4979	9	0.743
NC_008312_44	44.1|6722439|35|NC_008312|CRISPRCasFinder	6722439-6722473	35	NZ_CP046372	Spiroplasma citri strain LB 319 plasmid pScpLB319-1, complete sequence	34282-34316	9	0.743
NC_008312_44	44.1|6722439|35|NC_008312|CRISPRCasFinder	6722439-6722473	35	NZ_CP047439	Spiroplasma citri strain BLH-MB plasmid pSciBLHMB-2, complete sequence	59964-59998	9	0.743
NC_008312_44	44.1|6722439|35|NC_008312|CRISPRCasFinder	6722439-6722473	35	NZ_CP047440	Spiroplasma citri strain BLH-MB plasmid pSciBLHMB-3, complete sequence	3300-3334	9	0.743
NC_008312_44	44.1|6722439|35|NC_008312|CRISPRCasFinder	6722439-6722473	35	NZ_CP053310	Spiroplasma citri strain C5 plasmid pScpC5-6, complete sequence	12933-12967	9	0.743
NC_008312_44	44.1|6722439|35|NC_008312|CRISPRCasFinder	6722439-6722473	35	NZ_LR214952	Mycoplasma neurolyticum strain NCTC10166 plasmid 2	2400-2434	9	0.743
NC_008312_47	47.1|7278276|30|NC_008312|CRISPRCasFinder	7278276-7278305	30	NZ_LR134418	Legionella adelaidensis strain NCTC12735 genome assembly, plasmid: 9	90269-90298	9	0.7
NC_008312_23	23.1|2941370|38|NC_008312|CRT	2941370-2941407	38	NZ_CP015730	Bacillus cereus strain A1 plasmid pBCA1, complete sequence	77614-77651	10	0.737
NC_008312_23	23.1|2941370|38|NC_008312|CRT	2941370-2941407	38	NC_015511	Haliscomenobacter hydrossis DSM 1100 plasmid pHALHY01, complete sequence	2201-2238	10	0.737
NC_008312_23	23.3|2941508|33|NC_008312|CRT	2941508-2941540	33	NC_008270	Rhodococcus jostii RHA1 plasmid pRHL2, complete sequence	244333-244365	10	0.697
NC_008312_23	23.4|2941561|38|NC_008312|CRT	2941561-2941598	38	NZ_CP015730	Bacillus cereus strain A1 plasmid pBCA1, complete sequence	77621-77658	10	0.737
NC_008312_23	23.6|2941688|38|NC_008312|CRT	2941688-2941725	38	NZ_CP015730	Bacillus cereus strain A1 plasmid pBCA1, complete sequence	77642-77679	10	0.737
NC_008312_3	3.62|616750|47|NC_008312|CRT	616750-616796	47	NZ_CP024776	Bacillus thuringiensis LM1212 plasmid pLM8, complete sequence	2305-2351	11	0.766
NC_008312_44	44.1|6722439|35|NC_008312|CRISPRCasFinder	6722439-6722473	35	NC_010927	Rickettsia monacensis strain IrR/Munich plasmid pRM, complete sequence	19223-19257	11	0.686
NC_008312_21	21.51|2629736|40|NC_008312|CRT	2629736-2629775	40	NC_015511	Haliscomenobacter hydrossis DSM 1100 plasmid pHALHY01, complete sequence	2202-2241	12	0.7
NC_008312_21	21.4|2627320|47|NC_008312|CRT	2627320-2627366	47	NZ_CP015730	Bacillus cereus strain A1 plasmid pBCA1, complete sequence	77613-77659	14	0.702

1. spacer 10.1|1399212|19|NC_008312|CRISPRCasFinder matches to NC_019772 (Anabaena cylindrica PCC 7122 plasmid pANACY.01, complete sequence) position: , mismatch: 0, identity: 1.0

agaagttaaaagtcaaaag	CRISPR spacer
agaagttaaaagtcaaaag	Protospacer
*******************

2. spacer 10.1|1399212|19|NC_008312|CRISPRCasFinder matches to NC_019772 (Anabaena cylindrica PCC 7122 plasmid pANACY.01, complete sequence) position: , mismatch: 0, identity: 1.0

agaagttaaaagtcaaaag	CRISPR spacer
agaagttaaaagtcaaaag	Protospacer
*******************

3. spacer 3.3|613048|20|NC_008312|CRT matches to MH153812 (Rhodococcus phage Grayson, complete genome) position: , mismatch: 1, identity: 0.95

tggcaccaataggaccagcc	CRISPR spacer
tggcaccaataggaccagca	Protospacer
******************* 

4. spacer 23.1|2941370|38|NC_008312|CRT matches to NZ_CP015730 (Bacillus cereus strain A1 plasmid pBCA1, complete sequence) position: , mismatch: 1, identity: 0.974

tttaggttttaggttttaggttttaggttttaagtttt	CRISPR spacer
tttaggttttaggttttaggttttaggttttaggtttt	Protospacer
********************************.*****

5. spacer 23.1|2941370|38|NC_008312|CRT matches to NC_015511 (Haliscomenobacter hydrossis DSM 1100 plasmid pHALHY01, complete sequence) position: , mismatch: 1, identity: 0.974

tttaggttttaggttttaggttttaggttttaagtttt	CRISPR spacer
tttacgttttaggttttaggttttaggttttaagtttt	Protospacer
**** *********************************

6. spacer 21.3|2627277|25|NC_008312|CRT matches to NC_013547 (Helicobacter pylori plasmid pAL226, complete sequence) position: , mismatch: 2, identity: 0.92

tttgaggttttagtttt--aggtttga	CRISPR spacer
tttgaggttttagttttagaggttt--	Protospacer
*****************  ******  

7. spacer 21.6|2627443|25|NC_008312|CRT matches to NZ_CP015730 (Bacillus cereus strain A1 plasmid pBCA1, complete sequence) position: , mismatch: 2, identity: 0.92

tttgaggttttaggttttaggtgtt	CRISPR spacer
ttttaggttttaggttttaggtttt	Protospacer
*** ****************** **

8. spacer 21.6|2627443|25|NC_008312|CRT matches to NZ_CP015730 (Bacillus cereus strain A1 plasmid pBCA1, complete sequence) position: , mismatch: 2, identity: 0.92

tttgaggttttaggttttaggtgtt	CRISPR spacer
ttttaggttttaggttttaggtttt	Protospacer
*** ****************** **

9. spacer 21.6|2627443|25|NC_008312|CRT matches to NZ_CP015730 (Bacillus cereus strain A1 plasmid pBCA1, complete sequence) position: , mismatch: 2, identity: 0.92

tttgaggttttaggttttaggtgtt	CRISPR spacer
ttttaggttttaggttttaggtttt	Protospacer
*** ****************** **

10. spacer 21.6|2627443|25|NC_008312|CRT matches to NC_015511 (Haliscomenobacter hydrossis DSM 1100 plasmid pHALHY01, complete sequence) position: , mismatch: 2, identity: 0.92

tttgaggttttaggttttaggtgtt	CRISPR spacer
ttttaggttttaggttttaggtttt	Protospacer
*** ****************** **

11. spacer 23.1|2941370|38|NC_008312|CRT matches to NZ_CP015730 (Bacillus cereus strain A1 plasmid pBCA1, complete sequence) position: , mismatch: 2, identity: 0.947

tttaggttttaggttttaggttttaggttttaagtttt	CRISPR spacer
tttaggttttaggttttaggttttaggttttaggtttg	Protospacer
********************************.**** 

12. spacer 21.1|2627152|26|NC_008312|CRT matches to NC_015511 (Haliscomenobacter hydrossis DSM 1100 plasmid pHALHY01, complete sequence) position: , mismatch: 3, identity: 0.885

tttgaggttttaggtttgaagtttga	CRISPR spacer
ttttaggttttaggttttaagtttta	Protospacer
*** ************* ****** *

13. spacer 21.3|2627277|25|NC_008312|CRT matches to NZ_CP038909 (Piscirickettsia salmonis strain Psal-009 plasmid unnamed1, complete sequence) position: , mismatch: 3, identity: 0.88

tttgaggttttagttttaggtttga	CRISPR spacer
ttttaggttttagttttagttttaa	Protospacer
*** *************** ***.*

14. spacer 21.6|2627443|25|NC_008312|CRT matches to NZ_CP015730 (Bacillus cereus strain A1 plasmid pBCA1, complete sequence) position: , mismatch: 3, identity: 0.88

tttgaggttttaggttttaggtgtt	CRISPR spacer
ttttaggttttaggttttaggtttg	Protospacer
*** ****************** * 

15. spacer 21.6|2627443|25|NC_008312|CRT matches to MG592416 (Vibrio phage 1.032.O._10N.261.54.F5, partial genome) position: , mismatch: 3, identity: 0.88

tttgaggttttaggttttaggtgtt	CRISPR spacer
tttgaggttttagcgtttaggtgtc	Protospacer
*************  *********.

16. spacer 21.25|2628432|25|NC_008312|CRT matches to NC_017377 (Helicobacter pylori Puno120 plasmid pHPPN120, complete sequence) position: , mismatch: 3, identity: 0.88

tcaattttttgaggttttagtttta	CRISPR spacer
tacatattttgaggttttagtttta	Protospacer
*  ** *******************

17. spacer 21.25|2628432|25|NC_008312|CRT matches to NC_013547 (Helicobacter pylori plasmid pAL226, complete sequence) position: , mismatch: 3, identity: 0.88

tcaattttttgaggttttagtttta	CRISPR spacer
tacatattttgaggttttagtttta	Protospacer
*  ** *******************

18. spacer 23.1|2941370|38|NC_008312|CRT matches to NC_015511 (Haliscomenobacter hydrossis DSM 1100 plasmid pHALHY01, complete sequence) position: , mismatch: 3, identity: 0.921

tttaggttttaggttttaggttttaggttttaagtttt	CRISPR spacer
tttaggttttaggttttaggttttaagttttaggttta	Protospacer
*************************.******.**** 

19. spacer 3.24|614218|29|NC_008312|CRT matches to NC_017957 (Tistrella mobilis KA081020-065 plasmid pTM1, complete sequence) position: , mismatch: 4, identity: 0.862

taagaccaggaacaccatcagctccagcc	CRISPR spacer
cacgtccaggaacaccatcagccccagcc	Protospacer
.* * *****************.******

20. spacer 3.33|614713|29|NC_008312|CRT matches to NC_017957 (Tistrella mobilis KA081020-065 plasmid pTM1, complete sequence) position: , mismatch: 4, identity: 0.862

taagaccaggaacaccatcagctccagcc	CRISPR spacer
cacgtccaggaacaccatcagccccagcc	Protospacer
.* * *****************.******

21. spacer 12.14|1607246|27|NC_008312|CRT matches to MN831413 (Enterococcus faecium strain M17/0314 plasmid pM17/0314, complete sequence) position: , mismatch: 4, identity: 0.852

tcaattattggcttttttagttatcag	CRISPR spacer
tgaaatatttgcttttttagttatcgg	Protospacer
* ** **** ***************.*

22. spacer 12.14|1607246|27|NC_008312|CRT matches to NZ_LT598665 (Enterococcus faecium isolate Ef_aus00233 plasmid 3) position: , mismatch: 4, identity: 0.852

tcaattattggcttttttagttatcag	CRISPR spacer
tgaaatatttgcttttttagttatcgg	Protospacer
* ** **** ***************.*

23. spacer 21.6|2627443|25|NC_008312|CRT matches to NC_012696 (Roseophage EE36P1, complete genome) position: , mismatch: 4, identity: 0.84

tttgaggttttaggttttaggtgtt	CRISPR spacer
cctgaacttttaggttttaggtgtt	Protospacer
..***. ******************

24. spacer 21.14|2627879|25|NC_008312|CRT matches to NZ_CP021331 (Maritalea myrionectae strain HL2708#5 plasmid pHL2708X3, complete sequence) position: , mismatch: 4, identity: 0.84

ttacatctaaattttttgaggtttt	CRISPR spacer
ttacatctaaattctttgaggcatg	Protospacer
*************.*******. * 

25. spacer 21.14|2627879|25|NC_008312|CRT matches to KT337344 (Streptococcus phage phiARI0274b, partial genome) position: , mismatch: 4, identity: 0.84

ttacatctaaattttttgaggtttt	CRISPR spacer
tatcatctaaattttttgaggtatc	Protospacer
*  ******************* *.

26. spacer 21.14|2627879|25|NC_008312|CRT matches to NC_024361 (Streptococcus phage DCC1738, complete sequence) position: , mismatch: 4, identity: 0.84

ttacatctaaattttttgaggtttt	CRISPR spacer
tatcatctaaattttttgaggtatc	Protospacer
*  ******************* *.

27. spacer 21.14|2627879|25|NC_008312|CRT matches to KT337359 (Streptococcus phage phiARI0468b-3, partial genome) position: , mismatch: 4, identity: 0.84

ttacatctaaattttttgaggtttt	CRISPR spacer
tatcatctaaattttttgaggtatc	Protospacer
*  ******************* *.

28. spacer 21.14|2627879|25|NC_008312|CRT matches to KT337354 (Streptococcus phage phiARI0462, complete genome) position: , mismatch: 4, identity: 0.84

ttacatctaaattttttgaggtttt	CRISPR spacer
tatcatctaaattttttgaggtatc	Protospacer
*  ******************* *.

29. spacer 21.14|2627879|25|NC_008312|CRT matches to FR671410 (Streptococcus phage 8140) position: , mismatch: 4, identity: 0.84

ttacatctaaattttttgaggtttt	CRISPR spacer
tatcatctaaattttttgaggtatc	Protospacer
*  ******************* *.

30. spacer 21.14|2627879|25|NC_008312|CRT matches to KT337345 (Streptococcus phage phiARI0285-1, partial genome) position: , mismatch: 4, identity: 0.84

ttacatctaaattttttgaggtttt	CRISPR spacer
tatcatctaaattttttgaggtatc	Protospacer
*  ******************* *.

31. spacer 21.14|2627879|25|NC_008312|CRT matches to NC_031907 (Streptococcus phage phiARI0746, complete genome) position: , mismatch: 4, identity: 0.84

ttacatctaaattttttgaggtttt	CRISPR spacer
tatcatctaaattttttgaggtatc	Protospacer
*  ******************* *.

32. spacer 21.14|2627879|25|NC_008312|CRT matches to NC_024370 (Streptococcus phage IC1, complete sequence) position: , mismatch: 4, identity: 0.84

ttacatctaaattttttgaggtttt	CRISPR spacer
tatcatctaaattttttgaggtatc	Protospacer
*  ******************* *.

33. spacer 21.14|2627879|25|NC_008312|CRT matches to FR671405 (Streptococcus phage V22) position: , mismatch: 4, identity: 0.84

ttacatctaaattttttgaggtttt	CRISPR spacer
tatcatctaaattttttgaggtatc	Protospacer
*  ******************* *.

34. spacer 21.14|2627879|25|NC_008312|CRT matches to KT337352 (Streptococcus phage phiARI0460-1, complete genome) position: , mismatch: 4, identity: 0.84

ttacatctaaattttttgaggtttt	CRISPR spacer
tatcatctaaattttttgaggtatc	Protospacer
*  ******************* *.

35. spacer 21.14|2627879|25|NC_008312|CRT matches to KT337351 (Streptococcus phage phiARI0455b, partial genome) position: , mismatch: 4, identity: 0.84

ttacatctaaattttttgaggtttt	CRISPR spacer
tatcatctaaattttttgaggtatc	Protospacer
*  ******************* *.

36. spacer 21.14|2627879|25|NC_008312|CRT matches to FR671411 (Streptococcus phage 2167) position: , mismatch: 4, identity: 0.84

ttacatctaaattttttgaggtttt	CRISPR spacer
tatcatctaaattttttgaggtatc	Protospacer
*  ******************* *.

37. spacer 21.14|2627879|25|NC_008312|CRT matches to KT337369 (Streptococcus phage phiARI0831b, partial genome) position: , mismatch: 4, identity: 0.84

ttacatctaaattttttgaggtttt	CRISPR spacer
tatcatctaaattttttgaggtatc	Protospacer
*  ******************* *.

38. spacer 21.14|2627879|25|NC_008312|CRT matches to KT337362 (Streptococcus phage phiARI0598b, partial genome) position: , mismatch: 4, identity: 0.84

ttacatctaaattttttgaggtttt	CRISPR spacer
tatcatctaaattttttgaggtatc	Protospacer
*  ******************* *.

39. spacer 21.14|2627879|25|NC_008312|CRT matches to KT337340 (Streptococcus phage phiARI0031, complete genome) position: , mismatch: 4, identity: 0.84

ttacatctaaattttttgaggtttt	CRISPR spacer
tatcatctaaattttttgaggtatc	Protospacer
*  ******************* *.

40. spacer 21.14|2627879|25|NC_008312|CRT matches to KY065496 (Streptococcus phage IPP60, complete genome) position: , mismatch: 4, identity: 0.84

ttacatctaaattttttgaggtttt	CRISPR spacer
tatcatctaaattttttgaggtatc	Protospacer
*  ******************* *.

41. spacer 21.14|2627879|25|NC_008312|CRT matches to KY065505 (Streptococcus phage IPP69, complete genome) position: , mismatch: 4, identity: 0.84

ttacatctaaattttttgaggtttt	CRISPR spacer
tatcatctaaattttttgaggtatc	Protospacer
*  ******************* *.

42. spacer 21.14|2627879|25|NC_008312|CRT matches to KY065480 (Streptococcus phage IPP40, complete genome) position: , mismatch: 4, identity: 0.84

ttacatctaaattttttgaggtttt	CRISPR spacer
tatcatctaaattttttgaggtatc	Protospacer
*  ******************* *.

43. spacer 21.14|2627879|25|NC_008312|CRT matches to KY065478 (Streptococcus phage IPP38, complete genome) position: , mismatch: 4, identity: 0.84

ttacatctaaattttttgaggtttt	CRISPR spacer
tatcatctaaattttttgaggtatc	Protospacer
*  ******************* *.

44. spacer 21.14|2627879|25|NC_008312|CRT matches to KY065486 (Streptococcus phage IPP46, complete genome) position: , mismatch: 4, identity: 0.84

ttacatctaaattttttgaggtttt	CRISPR spacer
tatcatctaaattttttgaggtatc	Protospacer
*  ******************* *.

45. spacer 21.14|2627879|25|NC_008312|CRT matches to KY065500 (Streptococcus phage IPP64, complete genome) position: , mismatch: 4, identity: 0.84

ttacatctaaattttttgaggtttt	CRISPR spacer
tatcatctaaattttttgaggtatc	Protospacer
*  ******************* *.

46. spacer 21.14|2627879|25|NC_008312|CRT matches to KY065452 (Streptococcus phage IPP10, complete genome) position: , mismatch: 4, identity: 0.84

ttacatctaaattttttgaggtttt	CRISPR spacer
tatcatctaaattttttgaggtatc	Protospacer
*  ******************* *.

47. spacer 21.19|2628169|26|NC_008312|CRT matches to NZ_CP019854 (Borreliella burgdorferi plasmid lp54, complete sequence) position: , mismatch: 4, identity: 0.846

tcatttttttgaggtgttaggtttta	CRISPR spacer
tcatttttttgagctgttagtttatt	Protospacer
************* ****** ** * 

48. spacer 21.19|2628169|26|NC_008312|CRT matches to NZ_CP019765 (Borreliella burgdorferi strain B31_NRZ isolate B31 plasmid p_lp54, complete sequence) position: , mismatch: 4, identity: 0.846

tcatttttttgaggtgttaggtttta	CRISPR spacer
tcatttttttgagctgttagtttatt	Protospacer
************* ****** ** * 

49. spacer 21.19|2628169|26|NC_008312|CRT matches to NC_011784 (Borreliella burgdorferi ZS7 plasmid ZS7_lp54, complete sequence) position: , mismatch: 4, identity: 0.846

tcatttttttgaggtgttaggtttta	CRISPR spacer
tcatttttttgagctgttagtttatt	Protospacer
************* ****** ** * 

50. spacer 21.19|2628169|26|NC_008312|CRT matches to NC_001857 (Borreliella burgdorferi B31 plasmid lp54, complete sequence) position: , mismatch: 4, identity: 0.846

tcatttttttgaggtgttaggtttta	CRISPR spacer
tcatttttttgagctgttagtttatt	Protospacer
************* ****** ** * 

51. spacer 21.21|2628250|26|NC_008312|CRT matches to NZ_CP019854 (Borreliella burgdorferi plasmid lp54, complete sequence) position: , mismatch: 4, identity: 0.846

tcatttttttgaggtgttaggtttta	CRISPR spacer
tcatttttttgagctgttagtttatt	Protospacer
************* ****** ** * 

52. spacer 21.21|2628250|26|NC_008312|CRT matches to NZ_CP019765 (Borreliella burgdorferi strain B31_NRZ isolate B31 plasmid p_lp54, complete sequence) position: , mismatch: 4, identity: 0.846

tcatttttttgaggtgttaggtttta	CRISPR spacer
tcatttttttgagctgttagtttatt	Protospacer
************* ****** ** * 

53. spacer 21.21|2628250|26|NC_008312|CRT matches to NC_011784 (Borreliella burgdorferi ZS7 plasmid ZS7_lp54, complete sequence) position: , mismatch: 4, identity: 0.846

tcatttttttgaggtgttaggtttta	CRISPR spacer
tcatttttttgagctgttagtttatt	Protospacer
************* ****** ** * 

54. spacer 21.21|2628250|26|NC_008312|CRT matches to NC_001857 (Borreliella burgdorferi B31 plasmid lp54, complete sequence) position: , mismatch: 4, identity: 0.846

tcatttttttgaggtgttaggtttta	CRISPR spacer
tcatttttttgagctgttagtttatt	Protospacer
************* ****** ** * 

55. spacer 21.24|2628389|25|NC_008312|CRT matches to NC_017364 (Helicobacter pylori Gambia94/24 plasmid, complete sequence) position: , mismatch: 4, identity: 0.84

tcatttttttgaggttttagtttta	CRISPR spacer
tattttttttggggttttagttttt	Protospacer
*  ********.************ 

56. spacer 21.24|2628389|25|NC_008312|CRT matches to NC_017377 (Helicobacter pylori Puno120 plasmid pHPPN120, complete sequence) position: , mismatch: 4, identity: 0.84

tcatttttttgaggttttagtttta	CRISPR spacer
tacatattttgaggttttagtttta	Protospacer
*   * *******************

57. spacer 21.24|2628389|25|NC_008312|CRT matches to NC_013547 (Helicobacter pylori plasmid pAL226, complete sequence) position: , mismatch: 4, identity: 0.84

tcatttttttgaggttttagtttta	CRISPR spacer
tacatattttgaggttttagtttta	Protospacer
*   * *******************

58. spacer 21.24|2628389|25|NC_008312|CRT matches to AP018320 (Nostoc sp. HK-01 plasmid plasmid2 DNA, complete genome) position: , mismatch: 4, identity: 0.84

tcatttttttgaggttttagtttta	CRISPR spacer
gcattttttagaggttttaattttt	Protospacer
 ******** *********.**** 

59. spacer 21.24|2628389|25|NC_008312|CRT matches to KF751797 (Campylobacter phage CJIE4-5, complete genome) position: , mismatch: 4, identity: 0.84

tcatttttttgaggttttagtttta	CRISPR spacer
gcattttttggagattttagttttt	Protospacer
 ******** ***.********** 

60. spacer 21.24|2628389|25|NC_008312|CRT matches to KF751794 (Campylobacter phage CJIE4-2, complete genome) position: , mismatch: 4, identity: 0.84

tcatttttttgaggttttagtttta	CRISPR spacer
gcattttttggagattttagttttt	Protospacer
 ******** ***.********** 

61. spacer 21.24|2628389|25|NC_008312|CRT matches to KF751795 (Campylobacter phage CJIE4-3, complete genome) position: , mismatch: 4, identity: 0.84

tcatttttttgaggttttagtttta	CRISPR spacer
gcattttttggagattttagttttt	Protospacer
 ******** ***.********** 

62. spacer 21.24|2628389|25|NC_008312|CRT matches to KF751796 (Campylobacter phage CJIE4-4, complete genome) position: , mismatch: 4, identity: 0.84

tcatttttttgaggttttagtttta	CRISPR spacer
gcattttttggagattttagttttt	Protospacer
 ******** ***.********** 

63. spacer 21.24|2628389|25|NC_008312|CRT matches to KF751793 (Campylobacter phage CJIE4-1, complete genome) position: , mismatch: 4, identity: 0.84

tcatttttttgaggttttagtttta	CRISPR spacer
gcattttttggagattttagttttt	Protospacer
 ******** ***.********** 

64. spacer 21.24|2628389|25|NC_008312|CRT matches to NZ_CP019854 (Borreliella burgdorferi plasmid lp54, complete sequence) position: , mismatch: 4, identity: 0.84

tcatttttttgaggttttagtttta	CRISPR spacer
tcatttttttgagctgttagtttat	Protospacer
************* * *******  

65. spacer 21.24|2628389|25|NC_008312|CRT matches to NZ_CP019765 (Borreliella burgdorferi strain B31_NRZ isolate B31 plasmid p_lp54, complete sequence) position: , mismatch: 4, identity: 0.84

tcatttttttgaggttttagtttta	CRISPR spacer
tcatttttttgagctgttagtttat	Protospacer
************* * *******  

66. spacer 21.24|2628389|25|NC_008312|CRT matches to NC_011784 (Borreliella burgdorferi ZS7 plasmid ZS7_lp54, complete sequence) position: , mismatch: 4, identity: 0.84

tcatttttttgaggttttagtttta	CRISPR spacer
tcatttttttgagctgttagtttat	Protospacer
************* * *******  

67. spacer 21.24|2628389|25|NC_008312|CRT matches to NC_001857 (Borreliella burgdorferi B31 plasmid lp54, complete sequence) position: , mismatch: 4, identity: 0.84

tcatttttttgaggttttagtttta	CRISPR spacer
tcatttttttgagctgttagtttat	Protospacer
************* * *******  

68. spacer 21.25|2628432|25|NC_008312|CRT matches to NZ_KM583814 (Helicobacter pylori strain UM134 plasmid pUM134, complete sequence) position: , mismatch: 4, identity: 0.84

tcaattttttgaggttttagtttta	CRISPR spacer
tacatattttgaggttttagttttt	Protospacer
*  ** ****************** 

69. spacer 21.25|2628432|25|NC_008312|CRT matches to NZ_CP018745 (Borreliella garinii strain CIP 103362 isolate 20047 plasmid p_lp54_linear) position: , mismatch: 4, identity: 0.84

tcaattttttgaggttttagtttta	CRISPR spacer
ttgattttttgaagttttagttttt	Protospacer
*..*********.*********** 

70. spacer 21.25|2628432|25|NC_008312|CRT matches to NZ_CP028862 (Borreliella garinii strain 20047 plasmid lp54, complete sequence) position: , mismatch: 4, identity: 0.84

tcaattttttgaggttttagtttta	CRISPR spacer
ttgattttttgaagttttagttttt	Protospacer
*..*********.*********** 

71. spacer 21.25|2628432|25|NC_008312|CRT matches to NC_017804 (Borreliella garinii BgVir plasmid lp54, complete sequence) position: , mismatch: 4, identity: 0.84

tcaattttttgaggttttagtttta	CRISPR spacer
ttgattttttgaagttttagttttt	Protospacer
*..*********.*********** 

72. spacer 21.25|2628432|25|NC_008312|CRT matches to NZ_MK795207 (Helicobacter pylori strain Yak16 plasmid pY16, complete sequence) position: , mismatch: 4, identity: 0.84

tcaattttttgaggttttagtttta	CRISPR spacer
tacatattttgaggttttagttttt	Protospacer
*  ** ****************** 

73. spacer 21.25|2628432|25|NC_008312|CRT matches to MN694029 (Marine virus AFVG_250M395, complete genome) position: , mismatch: 4, identity: 0.84

tcaattttttgaggttttagtttta	CRISPR spacer
ttaattttttgaggttttggtttct	Protospacer
*.****************.****. 

74. spacer 21.28|2628549|25|NC_008312|CRT matches to NC_017364 (Helicobacter pylori Gambia94/24 plasmid, complete sequence) position: , mismatch: 4, identity: 0.84

tcatttttttgaggttttagtttta	CRISPR spacer
tattttttttggggttttagttttt	Protospacer
*  ********.************ 

75. spacer 21.28|2628549|25|NC_008312|CRT matches to NC_017377 (Helicobacter pylori Puno120 plasmid pHPPN120, complete sequence) position: , mismatch: 4, identity: 0.84

tcatttttttgaggttttagtttta	CRISPR spacer
tacatattttgaggttttagtttta	Protospacer
*   * *******************

76. spacer 21.28|2628549|25|NC_008312|CRT matches to NC_013547 (Helicobacter pylori plasmid pAL226, complete sequence) position: , mismatch: 4, identity: 0.84

tcatttttttgaggttttagtttta	CRISPR spacer
tacatattttgaggttttagtttta	Protospacer
*   * *******************

77. spacer 21.28|2628549|25|NC_008312|CRT matches to AP018320 (Nostoc sp. HK-01 plasmid plasmid2 DNA, complete genome) position: , mismatch: 4, identity: 0.84

tcatttttttgaggttttagtttta	CRISPR spacer
gcattttttagaggttttaattttt	Protospacer
 ******** *********.**** 

78. spacer 21.28|2628549|25|NC_008312|CRT matches to KF751797 (Campylobacter phage CJIE4-5, complete genome) position: , mismatch: 4, identity: 0.84

tcatttttttgaggttttagtttta	CRISPR spacer
gcattttttggagattttagttttt	Protospacer
 ******** ***.********** 

79. spacer 21.28|2628549|25|NC_008312|CRT matches to KF751794 (Campylobacter phage CJIE4-2, complete genome) position: , mismatch: 4, identity: 0.84

tcatttttttgaggttttagtttta	CRISPR spacer
gcattttttggagattttagttttt	Protospacer
 ******** ***.********** 

80. spacer 21.28|2628549|25|NC_008312|CRT matches to KF751795 (Campylobacter phage CJIE4-3, complete genome) position: , mismatch: 4, identity: 0.84

tcatttttttgaggttttagtttta	CRISPR spacer
gcattttttggagattttagttttt	Protospacer
 ******** ***.********** 

81. spacer 21.28|2628549|25|NC_008312|CRT matches to KF751796 (Campylobacter phage CJIE4-4, complete genome) position: , mismatch: 4, identity: 0.84

tcatttttttgaggttttagtttta	CRISPR spacer
gcattttttggagattttagttttt	Protospacer
 ******** ***.********** 

82. spacer 21.28|2628549|25|NC_008312|CRT matches to KF751793 (Campylobacter phage CJIE4-1, complete genome) position: , mismatch: 4, identity: 0.84

tcatttttttgaggttttagtttta	CRISPR spacer
gcattttttggagattttagttttt	Protospacer
 ******** ***.********** 

83. spacer 21.28|2628549|25|NC_008312|CRT matches to NZ_CP019854 (Borreliella burgdorferi plasmid lp54, complete sequence) position: , mismatch: 4, identity: 0.84

tcatttttttgaggttttagtttta	CRISPR spacer
tcatttttttgagctgttagtttat	Protospacer
************* * *******  

84. spacer 21.28|2628549|25|NC_008312|CRT matches to NZ_CP019765 (Borreliella burgdorferi strain B31_NRZ isolate B31 plasmid p_lp54, complete sequence) position: , mismatch: 4, identity: 0.84

tcatttttttgaggttttagtttta	CRISPR spacer
tcatttttttgagctgttagtttat	Protospacer
************* * *******  

85. spacer 21.28|2628549|25|NC_008312|CRT matches to NC_011784 (Borreliella burgdorferi ZS7 plasmid ZS7_lp54, complete sequence) position: , mismatch: 4, identity: 0.84

tcatttttttgaggttttagtttta	CRISPR spacer
tcatttttttgagctgttagtttat	Protospacer
************* * *******  

86. spacer 21.28|2628549|25|NC_008312|CRT matches to NC_001857 (Borreliella burgdorferi B31 plasmid lp54, complete sequence) position: , mismatch: 4, identity: 0.84

tcatttttttgaggttttagtttta	CRISPR spacer
tcatttttttgagctgttagtttat	Protospacer
************* * *******  

87. spacer 21.31|2628666|26|NC_008312|CRT matches to NZ_CP011146 (Bacillus cereus strain FORC_013 plasmid pFORC13, complete sequence) position: , mismatch: 4, identity: 0.846

ttaagtctcaattttttgaggcttta	CRISPR spacer
ataagtctcaattttttgatgcgttt	Protospacer
 ****************** ** ** 

88. spacer 21.31|2628666|26|NC_008312|CRT matches to MN693653 (Marine virus AFVG_250M591, complete genome) position: , mismatch: 4, identity: 0.846

ttaagtctcaattttttgaggcttta	CRISPR spacer
atgagtctcaattctttgaagcttta	Protospacer
 *.**********.*****.******

89. spacer 21.38|2628979|26|NC_008312|CRT matches to KY926699 (Lactococcus phage PLgY-30, complete genome) position: , mismatch: 4, identity: 0.846

tgaagtttgaggtttgaggtctcaat	CRISPR spacer
acaagtttgatgtttgaggtttcaat	Protospacer
  ******** *********.*****

90. spacer 21.38|2628979|26|NC_008312|CRT matches to KY888143 (Lactococcus phage PLgW-1, complete genome) position: , mismatch: 4, identity: 0.846

tgaagtttgaggtttgaggtctcaat	CRISPR spacer
acaagtttgatgtttgaggtttcaat	Protospacer
  ******** *********.*****

91. spacer 21.38|2628979|26|NC_008312|CRT matches to KY926698 (Lactococcus phage PLgY-16, complete genome) position: , mismatch: 4, identity: 0.846

tgaagtttgaggtttgaggtctcaat	CRISPR spacer
acaagtttgatgtttgaggtttcaat	Protospacer
  ******** *********.*****

92. spacer 21.42|2629161|26|NC_008312|CRT matches to KY926699 (Lactococcus phage PLgY-30, complete genome) position: , mismatch: 4, identity: 0.846

tgaagtttgaggtttgaggtctcaat	CRISPR spacer
acaagtttgatgtttgaggtttcaat	Protospacer
  ******** *********.*****

93. spacer 21.42|2629161|26|NC_008312|CRT matches to KY888143 (Lactococcus phage PLgW-1, complete genome) position: , mismatch: 4, identity: 0.846

tgaagtttgaggtttgaggtctcaat	CRISPR spacer
acaagtttgatgtttgaggtttcaat	Protospacer
  ******** *********.*****

94. spacer 21.42|2629161|26|NC_008312|CRT matches to KY926698 (Lactococcus phage PLgY-16, complete genome) position: , mismatch: 4, identity: 0.846

tgaagtttgaggtttgaggtctcaat	CRISPR spacer
acaagtttgatgtttgaggtttcaat	Protospacer
  ******** *********.*****

95. spacer 21.58|2630150|26|NC_008312|CRT matches to KY926699 (Lactococcus phage PLgY-30, complete genome) position: , mismatch: 4, identity: 0.846

tgaagtttgaagtttgaggtctcaat	CRISPR spacer
acaagtttgatgtttgaggtttcaat	Protospacer
  ******** *********.*****

96. spacer 21.58|2630150|26|NC_008312|CRT matches to KY888143 (Lactococcus phage PLgW-1, complete genome) position: , mismatch: 4, identity: 0.846

tgaagtttgaagtttgaggtctcaat	CRISPR spacer
acaagtttgatgtttgaggtttcaat	Protospacer
  ******** *********.*****

97. spacer 21.58|2630150|26|NC_008312|CRT matches to KY926698 (Lactococcus phage PLgY-16, complete genome) position: , mismatch: 4, identity: 0.846

tgaagtttgaagtttgaggtctcaat	CRISPR spacer
acaagtttgatgtttgaggtttcaat	Protospacer
  ******** *********.*****

98. spacer 23.1|2941370|38|NC_008312|CRT matches to NZ_CP015730 (Bacillus cereus strain A1 plasmid pBCA1, complete sequence) position: , mismatch: 4, identity: 0.895

tttaggttttaggttttaggttttaggttttaagtttt	CRISPR spacer
gtacggttttaggttttaggttttaggttttaggtttt	Protospacer
 *  ****************************.*****

99. spacer 48.4|7295333|25|NC_008312|CRISPRCasFinder matches to KU686211 (Synechococcus phage S-WAM2 isolate 0810PA29, complete genome) position: , mismatch: 4, identity: 0.84

tgaagataaaagcgatgtccttgaa	CRISPR spacer
tgaagataaaagtgaagtccttggt	Protospacer
************.** *******. 

100. spacer 48.4|7295333|25|NC_008312|CRISPRCasFinder matches to MT162468 (Synechococcus phage S-H25, complete genome) position: , mismatch: 4, identity: 0.84

tgaagataaaagcgatgtccttgaa	CRISPR spacer
tgaagataaaagtgaagtccttggt	Protospacer
************.** *******. 

101. spacer 48.4|7295333|25|NC_008312|CRISPRCasFinder matches to NC_031944 (Synechococcus phage S-WAM1 isolate 0810PA09, complete genome) position: , mismatch: 4, identity: 0.84

tgaagataaaagcgatgtccttgaa	CRISPR spacer
tgaagataaaagtgaagtccttggt	Protospacer
************.** *******. 

102. spacer 48.4|7295333|25|NC_008312|CRISPRCasFinder matches to MW117966 (Synechococcus phage S-H9-1, complete genome) position: , mismatch: 4, identity: 0.84

tgaagataaaagcgatgtccttgaa	CRISPR spacer
tgaagataaaagtgaagtccttggt	Protospacer
************.** *******. 

103. spacer 48.4|7295333|25|NC_008312|CRISPRCasFinder matches to NC_013085 (Synechococcus phage S-RSM4, complete genome) position: , mismatch: 4, identity: 0.84

tgaagataaaagcgatgtccttgaa	CRISPR spacer
tgaagataaaagtgaagtccttggt	Protospacer
************.** *******. 

104. spacer 48.4|7295333|25|NC_008312|CRISPRCasFinder matches to FM207411 (Synechococcus phage S-RSM4 complete genome) position: , mismatch: 4, identity: 0.84

tgaagataaaagcgatgtccttgaa	CRISPR spacer
tgaagataaaagtgaagtccttggt	Protospacer
************.** *******. 

105. spacer 3.4|613093|29|NC_008312|CRT matches to NC_041958 (Roseobacter phage RDJL Phi 2, complete genome) position: , mismatch: 5, identity: 0.828

taaaaccaggagcaccatcagctccagcc	CRISPR spacer
caacaccaggagcaccatcagcaccatca	Protospacer
.** ****************** *** * 

106. spacer 3.22|614119|29|NC_008312|CRT matches to NZ_CP022775 (Ralstonia solanacearum strain T12 plasmid unnamed, complete sequence) position: , mismatch: 5, identity: 0.828

caagaccaggaacaccatcagctccagcc	CRISPR spacer
cacatccaggaacaccatcagccccaggc	Protospacer
** . *****************.**** *

107. spacer 3.22|614119|29|NC_008312|CRT matches to NC_014310 (Ralstonia solanacearum PSI07 plasmid mpPSI07, complete sequence) position: , mismatch: 5, identity: 0.828

caagaccaggaacaccatcagctccagcc	CRISPR spacer
cacatccaggaacaccatcagccccaggc	Protospacer
** . *****************.**** *

108. spacer 3.22|614119|29|NC_008312|CRT matches to NZ_CP022762 (Ralstonia solanacearum strain T95 plasmid unnamed, complete sequence) position: , mismatch: 5, identity: 0.828

caagaccaggaacaccatcagctccagcc	CRISPR spacer
cacatccaggaacaccatcagccccaggc	Protospacer
** . *****************.**** *

109. spacer 3.22|614119|29|NC_008312|CRT matches to NZ_CP023017 (Ralstonia solanacearum strain SL3022 plasmid unnamed, complete sequence) position: , mismatch: 5, identity: 0.828

caagaccaggaacaccatcagctccagcc	CRISPR spacer
cacatccaggaacaccatcagccccaggc	Protospacer
** . *****************.**** *

110. spacer 3.22|614119|29|NC_008312|CRT matches to NZ_CP014703 (Ralstonia solanacearum strain KACC 10722 plasmid, complete sequence) position: , mismatch: 5, identity: 0.828

caagaccaggaacaccatcagctccagcc	CRISPR spacer
cacatccaggaacaccatcagccccaggc	Protospacer
** . *****************.**** *

111. spacer 3.22|614119|29|NC_008312|CRT matches to NZ_CP022760 (Ralstonia solanacearum strain T98 plasmid unnamed, complete sequence) position: , mismatch: 5, identity: 0.828

caagaccaggaacaccatcagctccagcc	CRISPR spacer
cacatccaggaacaccatcagccccaggc	Protospacer
** . *****************.**** *

112. spacer 3.22|614119|29|NC_008312|CRT matches to NZ_CP022789 (Ralstonia solanacearum strain SL3175 plasmid unnamed, complete sequence) position: , mismatch: 5, identity: 0.828

caagaccaggaacaccatcagctccagcc	CRISPR spacer
cacatccaggaacaccatcagccccaggc	Protospacer
** . *****************.**** *

113. spacer 3.22|614119|29|NC_008312|CRT matches to NZ_CP022771 (Ralstonia solanacearum strain T51 plasmid unnamed, complete sequence) position: , mismatch: 5, identity: 0.828

caagaccaggaacaccatcagctccagcc	CRISPR spacer
cacatccaggaacaccatcagccccaggc	Protospacer
** . *****************.**** *

114. spacer 3.22|614119|29|NC_008312|CRT matches to NZ_CP022777 (Ralstonia solanacearum strain T11 plasmid unnamed, complete sequence) position: , mismatch: 5, identity: 0.828

caagaccaggaacaccatcagctccagcc	CRISPR spacer
cacatccaggaacaccatcagccccaggc	Protospacer
** . *****************.**** *

115. spacer 3.22|614119|29|NC_008312|CRT matches to NZ_CP022799 (Ralstonia solanacearum strain SL2064 plasmid unnamed, complete sequence) position: , mismatch: 5, identity: 0.828

caagaccaggaacaccatcagctccagcc	CRISPR spacer
cacatccaggaacaccatcagccccaggc	Protospacer
** . *****************.**** *

116. spacer 3.22|614119|29|NC_008312|CRT matches to NZ_CP022764 (Ralstonia solanacearum strain T82 plasmid unnamed, complete sequence) position: , mismatch: 5, identity: 0.828

caagaccaggaacaccatcagctccagcc	CRISPR spacer
cacatccaggaacaccatcagccccaggc	Protospacer
** . *****************.**** *

117. spacer 3.22|614119|29|NC_008312|CRT matches to NZ_CP022797 (Ralstonia solanacearum strain SL2312 plasmid unnamed, complete sequence) position: , mismatch: 5, identity: 0.828

caagaccaggaacaccatcagctccagcc	CRISPR spacer
cacatccaggaacaccatcagccccaggc	Protospacer
** . *****************.**** *

118. spacer 3.22|614119|29|NC_008312|CRT matches to NZ_CP022758 (Ralstonia solanacearum strain T101 plasmid unnamed, complete sequence) position: , mismatch: 5, identity: 0.828

caagaccaggaacaccatcagctccagcc	CRISPR spacer
cacatccaggaacaccatcagccccaggc	Protospacer
** . *****************.**** *

119. spacer 3.24|614218|29|NC_008312|CRT matches to NZ_CP012940 (Ralstonia solanacearum strain UW163 plasmid unnamed, complete sequence) position: , mismatch: 5, identity: 0.828

taagaccaggaacaccatcagctccagcc	CRISPR spacer
cacgtccaggaacaccatcagccccaggc	Protospacer
.* * *****************.**** *

120. spacer 3.24|614218|29|NC_008312|CRT matches to NZ_CP012944 (Ralstonia solanacearum strain IBSBF1503 plasmid unnamed, complete sequence) position: , mismatch: 5, identity: 0.828

taagaccaggaacaccatcagctccagcc	CRISPR spacer
cacgtccaggaacaccatcagccccaggc	Protospacer
.* * *****************.**** *

121. spacer 3.24|614218|29|NC_008312|CRT matches to NZ_CP051295 (Ralstonia solanacearum strain CIAT_078 plasmid megaplasmid, complete sequence) position: , mismatch: 5, identity: 0.828

taagaccaggaacaccatcagctccagcc	CRISPR spacer
cacgtccaggaacaccatcagccccaggc	Protospacer
.* * *****************.**** *

122. spacer 3.24|614218|29|NC_008312|CRT matches to NZ_CP026091 (Ralstonia solanacearum strain IBSBF 2570 plasmid unnamed, complete sequence) position: , mismatch: 5, identity: 0.828

taagaccaggaacaccatcagctccagcc	CRISPR spacer
cacgtccaggaacaccatcagccccaggc	Protospacer
.* * *****************.**** *

123. spacer 3.24|614218|29|NC_008312|CRT matches to NC_014309 (Ralstonia solanacearum CFBP2957 plasmid RCFBPv3_mp, complete genome) position: , mismatch: 5, identity: 0.828

taagaccaggaacaccatcagctccagcc	CRISPR spacer
cacgtccaggaacaccatcagccccaggc	Protospacer
.* * *****************.**** *

124. spacer 3.24|614218|29|NC_008312|CRT matches to NZ_CP021653 (Ralstonia solanacearum strain RS 488 plasmid unnamed, complete sequence) position: , mismatch: 5, identity: 0.828

taagaccaggaacaccatcagctccagcc	CRISPR spacer
cacgtccaggaacaccatcagccccaggc	Protospacer
.* * *****************.**** *

125. spacer 3.24|614218|29|NC_008312|CRT matches to NZ_CP026093 (Ralstonia solanacearum strain SFC plasmid unnamed, complete sequence) position: , mismatch: 5, identity: 0.828

taagaccaggaacaccatcagctccagcc	CRISPR spacer
cacgtccaggaacaccatcagccccaggc	Protospacer
.* * *****************.**** *

126. spacer 3.24|614218|29|NC_008312|CRT matches to NZ_CP021767 (Ralstonia solanacearum strain RS 489 plasmid unnamed, complete sequence) position: , mismatch: 5, identity: 0.828

taagaccaggaacaccatcagctccagcc	CRISPR spacer
cacgtccaggaacaccatcagccccaggc	Protospacer
.* * *****************.**** *

127. spacer 3.24|614218|29|NC_008312|CRT matches to NZ_CP012688 (Ralstonia solanacearum strain UY031 plasmid unnamed, complete sequence) position: , mismatch: 5, identity: 0.828

taagaccaggaacaccatcagctccagcc	CRISPR spacer
cacgtccaggaacaccatcagccccaggc	Protospacer
.* * *****************.**** *

128. spacer 3.24|614218|29|NC_008312|CRT matches to NC_017575 (Ralstonia solanacearum Po82 megaplasmid, complete sequence) position: , mismatch: 5, identity: 0.828

taagaccaggaacaccatcagctccagcc	CRISPR spacer
cacgtccaggaacaccatcagccccaggc	Protospacer
.* * *****************.**** *

129. spacer 3.24|614218|29|NC_008312|CRT matches to NZ_CP026308 (Ralstonia solanacearum strain IBSBF 2571 plasmid unnamed, complete sequence) position: , mismatch: 5, identity: 0.828

taagaccaggaacaccatcagctccagcc	CRISPR spacer
cacgtccaggaacaccatcagccccaggc	Protospacer
.* * *****************.**** *

130. spacer 3.24|614218|29|NC_008312|CRT matches to NZ_CP021765 (Ralstonia pseudosolanacearum strain CRMRs218 plasmid unnamed, complete sequence) position: , mismatch: 5, identity: 0.828

taagaccaggaacaccatcagctccagcc	CRISPR spacer
cacgtccaggaacaccatcagccccaggc	Protospacer
.* * *****************.**** *

131. spacer 3.24|614218|29|NC_008312|CRT matches to CP047139 (Ralstonia solanacearum strain CFBP 8695 plasmid unnamed, complete sequence) position: , mismatch: 5, identity: 0.828

taagaccaggaacaccatcagctccagcc	CRISPR spacer
cacgtccaggaacaccatcagccccaggc	Protospacer
.* * *****************.**** *

132. spacer 3.24|614218|29|NC_008312|CRT matches to CP047137 (Ralstonia solanacearum strain CFBP 8697 plasmid unnamed, complete sequence) position: , mismatch: 5, identity: 0.828

taagaccaggaacaccatcagctccagcc	CRISPR spacer
cacgtccaggaacaccatcagccccaggc	Protospacer
.* * *****************.**** *

133. spacer 3.29|614479|29|NC_008312|CRT matches to NC_007501 (Lactobacillus phage Lc-Nu, complete genome) position: , mismatch: 5, identity: 0.828

taagaccaggaacaccatcagctccagct	CRISPR spacer
ttgcaccaggaacaccatcagcaccatct	Protospacer
* . ****************** *** **

134. spacer 3.29|614479|29|NC_008312|CRT matches to AY131267 (Bacteriophage Lc-Nu, complete genome) position: , mismatch: 5, identity: 0.828

taagaccaggaacaccatcagctccagct	CRISPR spacer
ttgcaccaggaacaccatcagcaccatct	Protospacer
* . ****************** *** **

135. spacer 3.29|614479|29|NC_008312|CRT matches to NC_017957 (Tistrella mobilis KA081020-065 plasmid pTM1, complete sequence) position: , mismatch: 5, identity: 0.828

taagaccaggaacaccatcagctccagct	CRISPR spacer
cacgtccaggaacaccatcagccccagcc	Protospacer
.* * *****************.*****.

136. spacer 3.33|614713|29|NC_008312|CRT matches to NZ_CP012940 (Ralstonia solanacearum strain UW163 plasmid unnamed, complete sequence) position: , mismatch: 5, identity: 0.828

taagaccaggaacaccatcagctccagcc	CRISPR spacer
cacgtccaggaacaccatcagccccaggc	Protospacer
.* * *****************.**** *

137. spacer 3.33|614713|29|NC_008312|CRT matches to NZ_CP012944 (Ralstonia solanacearum strain IBSBF1503 plasmid unnamed, complete sequence) position: , mismatch: 5, identity: 0.828

taagaccaggaacaccatcagctccagcc	CRISPR spacer
cacgtccaggaacaccatcagccccaggc	Protospacer
.* * *****************.**** *

138. spacer 3.33|614713|29|NC_008312|CRT matches to NZ_CP051295 (Ralstonia solanacearum strain CIAT_078 plasmid megaplasmid, complete sequence) position: , mismatch: 5, identity: 0.828

taagaccaggaacaccatcagctccagcc	CRISPR spacer
cacgtccaggaacaccatcagccccaggc	Protospacer
.* * *****************.**** *

139. spacer 3.33|614713|29|NC_008312|CRT matches to NZ_CP026091 (Ralstonia solanacearum strain IBSBF 2570 plasmid unnamed, complete sequence) position: , mismatch: 5, identity: 0.828

taagaccaggaacaccatcagctccagcc	CRISPR spacer
cacgtccaggaacaccatcagccccaggc	Protospacer
.* * *****************.**** *

140. spacer 3.33|614713|29|NC_008312|CRT matches to NC_014309 (Ralstonia solanacearum CFBP2957 plasmid RCFBPv3_mp, complete genome) position: , mismatch: 5, identity: 0.828

taagaccaggaacaccatcagctccagcc	CRISPR spacer
cacgtccaggaacaccatcagccccaggc	Protospacer
.* * *****************.**** *

141. spacer 3.33|614713|29|NC_008312|CRT matches to NZ_CP021653 (Ralstonia solanacearum strain RS 488 plasmid unnamed, complete sequence) position: , mismatch: 5, identity: 0.828

taagaccaggaacaccatcagctccagcc	CRISPR spacer
cacgtccaggaacaccatcagccccaggc	Protospacer
.* * *****************.**** *

142. spacer 3.33|614713|29|NC_008312|CRT matches to NZ_CP026093 (Ralstonia solanacearum strain SFC plasmid unnamed, complete sequence) position: , mismatch: 5, identity: 0.828

taagaccaggaacaccatcagctccagcc	CRISPR spacer
cacgtccaggaacaccatcagccccaggc	Protospacer
.* * *****************.**** *

143. spacer 3.33|614713|29|NC_008312|CRT matches to NZ_CP021767 (Ralstonia solanacearum strain RS 489 plasmid unnamed, complete sequence) position: , mismatch: 5, identity: 0.828

taagaccaggaacaccatcagctccagcc	CRISPR spacer
cacgtccaggaacaccatcagccccaggc	Protospacer
.* * *****************.**** *

144. spacer 3.33|614713|29|NC_008312|CRT matches to NZ_CP012688 (Ralstonia solanacearum strain UY031 plasmid unnamed, complete sequence) position: , mismatch: 5, identity: 0.828

taagaccaggaacaccatcagctccagcc	CRISPR spacer
cacgtccaggaacaccatcagccccaggc	Protospacer
.* * *****************.**** *

145. spacer 3.33|614713|29|NC_008312|CRT matches to NC_017575 (Ralstonia solanacearum Po82 megaplasmid, complete sequence) position: , mismatch: 5, identity: 0.828

taagaccaggaacaccatcagctccagcc	CRISPR spacer
cacgtccaggaacaccatcagccccaggc	Protospacer
.* * *****************.**** *

146. spacer 3.33|614713|29|NC_008312|CRT matches to NZ_CP026308 (Ralstonia solanacearum strain IBSBF 2571 plasmid unnamed, complete sequence) position: , mismatch: 5, identity: 0.828

taagaccaggaacaccatcagctccagcc	CRISPR spacer
cacgtccaggaacaccatcagccccaggc	Protospacer
.* * *****************.**** *

147. spacer 3.33|614713|29|NC_008312|CRT matches to NZ_CP021765 (Ralstonia pseudosolanacearum strain CRMRs218 plasmid unnamed, complete sequence) position: , mismatch: 5, identity: 0.828

taagaccaggaacaccatcagctccagcc	CRISPR spacer
cacgtccaggaacaccatcagccccaggc	Protospacer
.* * *****************.**** *

148. spacer 3.33|614713|29|NC_008312|CRT matches to CP047139 (Ralstonia solanacearum strain CFBP 8695 plasmid unnamed, complete sequence) position: , mismatch: 5, identity: 0.828

taagaccaggaacaccatcagctccagcc	CRISPR spacer
cacgtccaggaacaccatcagccccaggc	Protospacer
.* * *****************.**** *

149. spacer 3.33|614713|29|NC_008312|CRT matches to CP047137 (Ralstonia solanacearum strain CFBP 8697 plasmid unnamed, complete sequence) position: , mismatch: 5, identity: 0.828

taagaccaggaacaccatcagctccagcc	CRISPR spacer
cacgtccaggaacaccatcagccccaggc	Protospacer
.* * *****************.**** *

150. spacer 3.35|614830|29|NC_008312|CRT matches to NC_009128 (Corynebacterium sp. L2-79-05 plasmid pLEW279a, complete sequence) position: , mismatch: 5, identity: 0.828

caagaccaggaacaccatcagctccagct	CRISPR spacer
cgaaaccaggaacaccatctgctcctggt	Protospacer
*.*.*************** ***** * *

151. spacer 3.35|614830|29|NC_008312|CRT matches to NZ_CP004352 (Corynebacterium casei LMG S-19264 plasmid pCASE2, complete sequence) position: , mismatch: 5, identity: 0.828

caagaccaggaacaccatcagctccagct	CRISPR spacer
cgaaaccaggaacaccatctgctcctggt	Protospacer
*.*.*************** ***** * *

152. spacer 3.40|615091|29|NC_008312|CRT matches to NC_007501 (Lactobacillus phage Lc-Nu, complete genome) position: , mismatch: 5, identity: 0.828

taagaccaggaacaccatcagctccagct	CRISPR spacer
ttgcaccaggaacaccatcagcaccatct	Protospacer
* . ****************** *** **

153. spacer 3.40|615091|29|NC_008312|CRT matches to AY131267 (Bacteriophage Lc-Nu, complete genome) position: , mismatch: 5, identity: 0.828

taagaccaggaacaccatcagctccagct	CRISPR spacer
ttgcaccaggaacaccatcagcaccatct	Protospacer
* . ****************** *** **

154. spacer 3.40|615091|29|NC_008312|CRT matches to NC_017957 (Tistrella mobilis KA081020-065 plasmid pTM1, complete sequence) position: , mismatch: 5, identity: 0.828

taagaccaggaacaccatcagctccagct	CRISPR spacer
cacgtccaggaacaccatcagccccagcc	Protospacer
.* * *****************.*****.

155. spacer 3.45|615433|29|NC_008312|CRT matches to NC_009128 (Corynebacterium sp. L2-79-05 plasmid pLEW279a, complete sequence) position: , mismatch: 5, identity: 0.828

caagaccaggaacaccatcagctccagct	CRISPR spacer
cgaaaccaggaacaccatctgctcctggt	Protospacer
*.*.*************** ***** * *

156. spacer 3.45|615433|29|NC_008312|CRT matches to NZ_CP004352 (Corynebacterium casei LMG S-19264 plasmid pCASE2, complete sequence) position: , mismatch: 5, identity: 0.828

caagaccaggaacaccatcagctccagct	CRISPR spacer
cgaaaccaggaacaccatctgctcctggt	Protospacer
*.*.*************** ***** * *

157. spacer 4.2|617254|29|NC_008312|CRT matches to NZ_CP007797 (Azospirillum brasilense strain Az39 plasmid AbAZ39_p4, complete sequence) position: , mismatch: 5, identity: 0.828

caagaccagcgggaccaggagctccagtt	CRISPR spacer
cggggccagcgggaccagggcctccagtt	Protospacer
*..*.**************. ********

158. spacer 4.3|617317|29|NC_008312|CRT matches to NZ_CP022775 (Ralstonia solanacearum strain T12 plasmid unnamed, complete sequence) position: , mismatch: 5, identity: 0.828

caagaccaggaacaccatcagctccagcc	CRISPR spacer
cacatccaggaacaccatcagccccaggc	Protospacer
** . *****************.**** *

159. spacer 4.3|617317|29|NC_008312|CRT matches to NC_014310 (Ralstonia solanacearum PSI07 plasmid mpPSI07, complete sequence) position: , mismatch: 5, identity: 0.828

caagaccaggaacaccatcagctccagcc	CRISPR spacer
cacatccaggaacaccatcagccccaggc	Protospacer
** . *****************.**** *

160. spacer 4.3|617317|29|NC_008312|CRT matches to NZ_CP022762 (Ralstonia solanacearum strain T95 plasmid unnamed, complete sequence) position: , mismatch: 5, identity: 0.828

caagaccaggaacaccatcagctccagcc	CRISPR spacer
cacatccaggaacaccatcagccccaggc	Protospacer
** . *****************.**** *

161. spacer 4.3|617317|29|NC_008312|CRT matches to NZ_CP023017 (Ralstonia solanacearum strain SL3022 plasmid unnamed, complete sequence) position: , mismatch: 5, identity: 0.828

caagaccaggaacaccatcagctccagcc	CRISPR spacer
cacatccaggaacaccatcagccccaggc	Protospacer
** . *****************.**** *

162. spacer 4.3|617317|29|NC_008312|CRT matches to NZ_CP014703 (Ralstonia solanacearum strain KACC 10722 plasmid, complete sequence) position: , mismatch: 5, identity: 0.828

caagaccaggaacaccatcagctccagcc	CRISPR spacer
cacatccaggaacaccatcagccccaggc	Protospacer
** . *****************.**** *

163. spacer 4.3|617317|29|NC_008312|CRT matches to NZ_CP022760 (Ralstonia solanacearum strain T98 plasmid unnamed, complete sequence) position: , mismatch: 5, identity: 0.828

caagaccaggaacaccatcagctccagcc	CRISPR spacer
cacatccaggaacaccatcagccccaggc	Protospacer
** . *****************.**** *

164. spacer 4.3|617317|29|NC_008312|CRT matches to NZ_CP022789 (Ralstonia solanacearum strain SL3175 plasmid unnamed, complete sequence) position: , mismatch: 5, identity: 0.828

caagaccaggaacaccatcagctccagcc	CRISPR spacer
cacatccaggaacaccatcagccccaggc	Protospacer
** . *****************.**** *

165. spacer 4.3|617317|29|NC_008312|CRT matches to NZ_CP022771 (Ralstonia solanacearum strain T51 plasmid unnamed, complete sequence) position: , mismatch: 5, identity: 0.828

caagaccaggaacaccatcagctccagcc	CRISPR spacer
cacatccaggaacaccatcagccccaggc	Protospacer
** . *****************.**** *

166. spacer 4.3|617317|29|NC_008312|CRT matches to NZ_CP022777 (Ralstonia solanacearum strain T11 plasmid unnamed, complete sequence) position: , mismatch: 5, identity: 0.828

caagaccaggaacaccatcagctccagcc	CRISPR spacer
cacatccaggaacaccatcagccccaggc	Protospacer
** . *****************.**** *

167. spacer 4.3|617317|29|NC_008312|CRT matches to NZ_CP022799 (Ralstonia solanacearum strain SL2064 plasmid unnamed, complete sequence) position: , mismatch: 5, identity: 0.828

caagaccaggaacaccatcagctccagcc	CRISPR spacer
cacatccaggaacaccatcagccccaggc	Protospacer
** . *****************.**** *

168. spacer 4.3|617317|29|NC_008312|CRT matches to NZ_CP022764 (Ralstonia solanacearum strain T82 plasmid unnamed, complete sequence) position: , mismatch: 5, identity: 0.828

caagaccaggaacaccatcagctccagcc	CRISPR spacer
cacatccaggaacaccatcagccccaggc	Protospacer
** . *****************.**** *

169. spacer 4.3|617317|29|NC_008312|CRT matches to NZ_CP022797 (Ralstonia solanacearum strain SL2312 plasmid unnamed, complete sequence) position: , mismatch: 5, identity: 0.828

caagaccaggaacaccatcagctccagcc	CRISPR spacer
cacatccaggaacaccatcagccccaggc	Protospacer
** . *****************.**** *

170. spacer 4.3|617317|29|NC_008312|CRT matches to NZ_CP022758 (Ralstonia solanacearum strain T101 plasmid unnamed, complete sequence) position: , mismatch: 5, identity: 0.828

caagaccaggaacaccatcagctccagcc	CRISPR spacer
cacatccaggaacaccatcagccccaggc	Protospacer
** . *****************.**** *

171. spacer 4.5|617434|29|NC_008312|CRT matches to NZ_CP022775 (Ralstonia solanacearum strain T12 plasmid unnamed, complete sequence) position: , mismatch: 5, identity: 0.828

caagaccaggaacaccatcagctccagcc	CRISPR spacer
cacatccaggaacaccatcagccccaggc	Protospacer
** . *****************.**** *

172. spacer 4.5|617434|29|NC_008312|CRT matches to NC_014310 (Ralstonia solanacearum PSI07 plasmid mpPSI07, complete sequence) position: , mismatch: 5, identity: 0.828

caagaccaggaacaccatcagctccagcc	CRISPR spacer
cacatccaggaacaccatcagccccaggc	Protospacer
** . *****************.**** *

173. spacer 4.5|617434|29|NC_008312|CRT matches to NZ_CP022762 (Ralstonia solanacearum strain T95 plasmid unnamed, complete sequence) position: , mismatch: 5, identity: 0.828

caagaccaggaacaccatcagctccagcc	CRISPR spacer
cacatccaggaacaccatcagccccaggc	Protospacer
** . *****************.**** *

174. spacer 4.5|617434|29|NC_008312|CRT matches to NZ_CP023017 (Ralstonia solanacearum strain SL3022 plasmid unnamed, complete sequence) position: , mismatch: 5, identity: 0.828

caagaccaggaacaccatcagctccagcc	CRISPR spacer
cacatccaggaacaccatcagccccaggc	Protospacer
** . *****************.**** *

175. spacer 4.5|617434|29|NC_008312|CRT matches to NZ_CP014703 (Ralstonia solanacearum strain KACC 10722 plasmid, complete sequence) position: , mismatch: 5, identity: 0.828

caagaccaggaacaccatcagctccagcc	CRISPR spacer
cacatccaggaacaccatcagccccaggc	Protospacer
** . *****************.**** *

176. spacer 4.5|617434|29|NC_008312|CRT matches to NZ_CP022760 (Ralstonia solanacearum strain T98 plasmid unnamed, complete sequence) position: , mismatch: 5, identity: 0.828

caagaccaggaacaccatcagctccagcc	CRISPR spacer
cacatccaggaacaccatcagccccaggc	Protospacer
** . *****************.**** *

177. spacer 4.5|617434|29|NC_008312|CRT matches to NZ_CP022789 (Ralstonia solanacearum strain SL3175 plasmid unnamed, complete sequence) position: , mismatch: 5, identity: 0.828

caagaccaggaacaccatcagctccagcc	CRISPR spacer
cacatccaggaacaccatcagccccaggc	Protospacer
** . *****************.**** *

178. spacer 4.5|617434|29|NC_008312|CRT matches to NZ_CP022771 (Ralstonia solanacearum strain T51 plasmid unnamed, complete sequence) position: , mismatch: 5, identity: 0.828

caagaccaggaacaccatcagctccagcc	CRISPR spacer
cacatccaggaacaccatcagccccaggc	Protospacer
** . *****************.**** *

179. spacer 4.5|617434|29|NC_008312|CRT matches to NZ_CP022777 (Ralstonia solanacearum strain T11 plasmid unnamed, complete sequence) position: , mismatch: 5, identity: 0.828

caagaccaggaacaccatcagctccagcc	CRISPR spacer
cacatccaggaacaccatcagccccaggc	Protospacer
** . *****************.**** *

180. spacer 4.5|617434|29|NC_008312|CRT matches to NZ_CP022799 (Ralstonia solanacearum strain SL2064 plasmid unnamed, complete sequence) position: , mismatch: 5, identity: 0.828

caagaccaggaacaccatcagctccagcc	CRISPR spacer
cacatccaggaacaccatcagccccaggc	Protospacer
** . *****************.**** *

181. spacer 4.5|617434|29|NC_008312|CRT matches to NZ_CP022764 (Ralstonia solanacearum strain T82 plasmid unnamed, complete sequence) position: , mismatch: 5, identity: 0.828

caagaccaggaacaccatcagctccagcc	CRISPR spacer
cacatccaggaacaccatcagccccaggc	Protospacer
** . *****************.**** *

182. spacer 4.5|617434|29|NC_008312|CRT matches to NZ_CP022797 (Ralstonia solanacearum strain SL2312 plasmid unnamed, complete sequence) position: , mismatch: 5, identity: 0.828

caagaccaggaacaccatcagctccagcc	CRISPR spacer
cacatccaggaacaccatcagccccaggc	Protospacer
** . *****************.**** *

183. spacer 4.5|617434|29|NC_008312|CRT matches to NZ_CP022758 (Ralstonia solanacearum strain T101 plasmid unnamed, complete sequence) position: , mismatch: 5, identity: 0.828

caagaccaggaacaccatcagctccagcc	CRISPR spacer
cacatccaggaacaccatcagccccaggc	Protospacer
** . *****************.**** *

184. spacer 12.14|1607246|27|NC_008312|CRT matches to NC_011738 (Gloeothece citriformis PCC 7424 plasmid pP742401, complete sequence) position: , mismatch: 5, identity: 0.815

tcaattattggcttttttagttatcag	CRISPR spacer
ctaataattagcttttttagttatcat	Protospacer
..*** ***.**************** 

185. spacer 12.14|1607246|27|NC_008312|CRT matches to NC_004565 (Clostridium tetani E88 plasmid pE88, complete sequence) position: , mismatch: 5, identity: 0.815

tcaattattggcttttttagttatcag	CRISPR spacer
taatttattggcttttttagttattct	Protospacer
* * ********************.  

186. spacer 12.14|1607246|27|NC_008312|CRT matches to NC_004565 (Clostridium tetani E88 plasmid pE88, complete sequence) position: , mismatch: 5, identity: 0.815

tcaattattggcttttttagttatcag	CRISPR spacer
taatttattggcttttttagttattct	Protospacer
* * ********************.  

187. spacer 12.14|1607246|27|NC_008312|CRT matches to CP011075 (Brevibacillus laterosporus strain B9 plasmid unnamed1, complete sequence) position: , mismatch: 5, identity: 0.815

tcaattattggcttttttagttatcag	CRISPR spacer
gctatgattggcttttttagttttcat	Protospacer
 * ** **************** *** 

188. spacer 12.14|1607246|27|NC_008312|CRT matches to NZ_CP039730 (Enterococcus faecium strain ZY2 plasmid pZY2) position: , mismatch: 5, identity: 0.815

tcaattattggcttttttagttatcag	CRISPR spacer
tgaaatatttgcttttttagttatcgt	Protospacer
* ** **** ***************. 

189. spacer 12.14|1607246|27|NC_008312|CRT matches to NZ_CP009921 (Bacillus megaterium NBRC 15308 = ATCC 14581 plasmid pBMV_2, complete sequence) position: , mismatch: 5, identity: 0.815

tcaattattggcttttttagttatcag	CRISPR spacer
tggatttttggcttttttagttaacat	Protospacer
* .*** **************** ** 

190. spacer 12.14|1607246|27|NC_008312|CRT matches to NZ_MG640601 (Enterococcus faecium strain SRR6 plasmid pEMSRR6, complete sequence) position: , mismatch: 5, identity: 0.815

tcaattattggcttttttagttatcag	CRISPR spacer
tgaaatatttgcttttttagttatcgt	Protospacer
* ** **** ***************. 

191. spacer 12.14|1607246|27|NC_008312|CRT matches to NZ_CP035095 (Bacillus megaterium NBRC 15308 = ATCC 14581 plasmid unnamed1, complete sequence) position: , mismatch: 5, identity: 0.815

tcaattattggcttttttagttatcag	CRISPR spacer
tggatttttggcttttttagttaacat	Protospacer
* .*** **************** ** 

192. spacer 12.14|1607246|27|NC_008312|CRT matches to MK448842 (Streptococcus phage Javan110, complete genome) position: , mismatch: 5, identity: 0.815

tcaattattggcttttttagttatcag	CRISPR spacer
tctattattggctattttagttagtgg	Protospacer
** ********** ********* ..*

193. spacer 21.19|2628169|26|NC_008312|CRT matches to MK448601 (Streptococcus satellite phage Javan653, complete genome) position: , mismatch: 5, identity: 0.808

tcatttttttgaggtgttaggtttta	CRISPR spacer
gtattcttttgagttgttaggttttg	Protospacer
 .***.******* ***********.

194. spacer 21.21|2628250|26|NC_008312|CRT matches to MK448601 (Streptococcus satellite phage Javan653, complete genome) position: , mismatch: 5, identity: 0.808

tcatttttttgaggtgttaggtttta	CRISPR spacer
gtattcttttgagttgttaggttttg	Protospacer
 .***.******* ***********.

195. spacer 21.32|2628710|26|NC_008312|CRT matches to MN693047 (Marine virus AFVG_25M111, complete genome) position: , mismatch: 5, identity: 0.808

tcaattttttgaggttttaggtgtta	CRISPR spacer
ccaattttttgaggtgttaggtgacc	Protospacer
.************** ******* . 

196. spacer 21.32|2628710|26|NC_008312|CRT matches to MN693506 (Marine virus AFVG_25M112, complete genome) position: , mismatch: 5, identity: 0.808

tcaattttttgaggttttaggtgtta	CRISPR spacer
ccaattttttgaggtgttaggtgacc	Protospacer
.************** ******* . 

197. spacer 21.32|2628710|26|NC_008312|CRT matches to NZ_CP029750 (Staphylococcus aureus strain Smith plasmid pSS41, complete sequence) position: , mismatch: 5, identity: 0.808

tcaattttttgaggttttaggtgtta	CRISPR spacer
caaattttttgagttattaggtgttg	Protospacer
. *********** * *********.

198. spacer 21.51|2629736|40|NC_008312|CRT matches to NC_015511 (Haliscomenobacter hydrossis DSM 1100 plasmid pHALHY01, complete sequence) position: , mismatch: 5, identity: 0.875

ttaggttttaggttttaggttttaagtttgaggtctcatt	CRISPR spacer
ttaggttttaggttttaggttttaagttttaggtttagat	Protospacer
***************************** ****.* . *

199. spacer 29.1|3671521|26|NC_008312|CRISPRCasFinder matches to NZ_CP028970 (Aminobacter sp. MSH1 plasmid pUSP2, complete sequence) position: , mismatch: 5, identity: 0.808

aagcgaatattgatagtgctcaagct	CRISPR spacer
acccgaacattgatagtgctcaagag	Protospacer
*  ****.****************  

200. spacer 45.6|6864734|30|NC_008312|CRT matches to NZ_CP048816 (Caulobacter rhizosphaerae strain KCTC 52515 plasmid unnamed) position: , mismatch: 5, identity: 0.833

acggcgtggcggttggcgtggcggttggcg	CRISPR spacer
cggccgtggcggttggcgtggcggggggcg	Protospacer
  * ********************  ****

201. spacer 45.6|6864734|30|NC_008312|CRT matches to NZ_CP022365 (Azospirillum sp. TSH58 plasmid TSH58_p06, complete sequence) position: , mismatch: 5, identity: 0.833

acggcgtggcggttggcgtggcg--gttggcg	CRISPR spacer
acggcgtggcggtcggcgtggtgtagtagg--	Protospacer
*************.*******.*  ** **  

202. spacer 47.1|7278276|30|NC_008312|CRISPRCasFinder matches to NZ_CP021887 (Helicobacter apodemus strain SCJK1 plasmid unnamed, complete sequence) position: , mismatch: 5, identity: 0.833

tttatcaattctaaattctcattattattg	CRISPR spacer
ctaatcaattcaaaattttcattattattt	Protospacer
.* ******** *****.*********** 

203. spacer 48.1|7295144|25|NC_008312|CRISPRCasFinder matches to NZ_CP048608 (Pseudomonas fluorescens strain DR133 plasmid unnamed, complete sequence) position: , mismatch: 5, identity: 0.8

gggtgccggccacgactaccttcat	CRISPR spacer
cggtgccggctacgactaccttggg	Protospacer
 *********.*********** . 

204. spacer 3.4|613093|29|NC_008312|CRT matches to AY939844 (Prochlorococcus phage P-SSM2, complete genome) position: , mismatch: 6, identity: 0.793

taaaaccaggagcaccatcagctccagcc	CRISPR spacer
gaggaccaggagcaccatcatcaccagca	Protospacer
 *..**************** * ***** 

205. spacer 3.4|613093|29|NC_008312|CRT matches to NC_017957 (Tistrella mobilis KA081020-065 plasmid pTM1, complete sequence) position: , mismatch: 6, identity: 0.793

taaaaccaggagcaccatcagctccagcc	CRISPR spacer
cacgtccaggaacaccatcagccccagcc	Protospacer
.* . ******.**********.******

206. spacer 3.4|613093|29|NC_008312|CRT matches to HQ632825 (Prochlorococcus phage P-SSM5 genomic sequence) position: , mismatch: 6, identity: 0.793

taaaaccaggagcaccatcagctccagcc	CRISPR spacer
gaggaccaggagcaccatcatcaccagca	Protospacer
 *..**************** * ***** 

207. spacer 3.4|613093|29|NC_008312|CRT matches to MN116494 (Klebsiella phage vB_KpnP_Bp5, complete genome) position: , mismatch: 6, identity: 0.793

taaaaccaggagcaccatcagctccagcc	CRISPR spacer
cagcaccagcagcaccagcagctccagca	Protospacer
.*. ***** ******* ********** 

208. spacer 3.4|613093|29|NC_008312|CRT matches to NZ_CP053445 (Rhizobium leguminosarum bv. trifolii strain CC275e plasmid pRltCC275eA, complete sequence) position: , mismatch: 6, identity: 0.793

taaaaccaggagcaccatcagctccagcc	CRISPR spacer
aaaaaccaggagctccatcagcgcgcgcg	Protospacer
 ************ ******** *  ** 

209. spacer 3.22|614119|29|NC_008312|CRT matches to NZ_CP033220 (Parasedimentitalea marina strain W43 plasmid pW43A, complete sequence) position: , mismatch: 6, identity: 0.793

caagaccaggaacaccatcagctccagcc	CRISPR spacer
gatgaccacgaccaccatcagctccaaca	Protospacer
 * ***** ** **************.* 

210. spacer 3.22|614119|29|NC_008312|CRT matches to NZ_CP033220 (Parasedimentitalea marina strain W43 plasmid pW43A, complete sequence) position: , mismatch: 6, identity: 0.793

caagaccaggaacaccatcagctccagcc	CRISPR spacer
gatgaccacgaccaccatcagctccaaca	Protospacer
 * ***** ** **************.* 

211. spacer 3.22|614119|29|NC_008312|CRT matches to NZ_CP006909 (Clostridium botulinum CDC_1436 plasmid pCBG, complete sequence) position: , mismatch: 6, identity: 0.793

caagaccaggaacaccatcagctccagcc	CRISPR spacer
cattgccaggaagaccatcagctccacca	Protospacer
**  .******* ************* * 

212. spacer 3.22|614119|29|NC_008312|CRT matches to NZ_CP031095 (Clostridium botulinum strain CFSAN034200 plasmid p1_CDC51232, complete sequence) position: , mismatch: 6, identity: 0.793

caagaccaggaacaccatcagctccagcc	CRISPR spacer
cattgccaggaagaccatcagctccacca	Protospacer
**  .******* ************* * 

213. spacer 3.22|614119|29|NC_008312|CRT matches to NC_009128 (Corynebacterium sp. L2-79-05 plasmid pLEW279a, complete sequence) position: , mismatch: 6, identity: 0.793

caagaccaggaacaccatcagctccagcc	CRISPR spacer
cgaaaccaggaacaccatctgctcctggt	Protospacer
*.*.*************** ***** * .

214. spacer 3.22|614119|29|NC_008312|CRT matches to NZ_CP004352 (Corynebacterium casei LMG S-19264 plasmid pCASE2, complete sequence) position: , mismatch: 6, identity: 0.793

caagaccaggaacaccatcagctccagcc	CRISPR spacer
cgaaaccaggaacaccatctgctcctggt	Protospacer
*.*.*************** ***** * .

215. spacer 3.22|614119|29|NC_008312|CRT matches to NC_012654 (Clostridium botulinum Ba4 str. 657 plasmid pCLJ, complete sequence) position: , mismatch: 6, identity: 0.793

caagaccaggaacaccatcagctccagcc	CRISPR spacer
cattgccaggaagaccatcagctccacca	Protospacer
**  .******* ************* * 

216. spacer 3.22|614119|29|NC_008312|CRT matches to NZ_CP034811 (Paracoccus sp. Arc7-R13 plasmid unnamed1, complete sequence) position: , mismatch: 6, identity: 0.793

caagaccaggaacaccatcagctccagcc	CRISPR spacer
cagttccaggaacacgatcagcgccagcg	Protospacer
**.  ********** ****** ***** 

217. spacer 3.22|614119|29|NC_008312|CRT matches to NC_028835 (Lactobacillus phage CL2, complete genome) position: , mismatch: 6, identity: 0.793

caagaccaggaacaccatcagctccagcc	CRISPR spacer
taggaccgggaacaccatcagcaccatca	Protospacer
.*.****.************** *** * 

218. spacer 3.22|614119|29|NC_008312|CRT matches to KR905066 (Lactobacillus phage CL1, complete genome) position: , mismatch: 6, identity: 0.793

caagaccaggaacaccatcagctccagcc	CRISPR spacer
taggaccgggaacaccatcagcaccatca	Protospacer
.*.****.************** *** * 

219. spacer 3.22|614119|29|NC_008312|CRT matches to NC_028911 (Lactobacillus phage iLp1308, complete genome) position: , mismatch: 6, identity: 0.793

caagaccaggaacaccatcagctccagcc	CRISPR spacer
taggaccgggaacaccatcagcaccatca	Protospacer
.*.****.************** *** * 

220. spacer 3.24|614218|29|NC_008312|CRT matches to NC_007501 (Lactobacillus phage Lc-Nu, complete genome) position: , mismatch: 6, identity: 0.793

taagaccaggaacaccatcagctccagcc	CRISPR spacer
ttgcaccaggaacaccatcagcaccatct	Protospacer
* . ****************** *** *.

221. spacer 3.24|614218|29|NC_008312|CRT matches to AY131267 (Bacteriophage Lc-Nu, complete genome) position: , mismatch: 6, identity: 0.793

taagaccaggaacaccatcagctccagcc	CRISPR spacer
ttgcaccaggaacaccatcagcaccatct	Protospacer
* . ****************** *** *.

222. spacer 3.24|614218|29|NC_008312|CRT matches to NZ_CP022775 (Ralstonia solanacearum strain T12 plasmid unnamed, complete sequence) position: , mismatch: 6, identity: 0.793

taagaccaggaacaccatcagctccagcc	CRISPR spacer
cacatccaggaacaccatcagccccaggc	Protospacer
.* . *****************.**** *

223. spacer 3.24|614218|29|NC_008312|CRT matches to NC_014310 (Ralstonia solanacearum PSI07 plasmid mpPSI07, complete sequence) position: , mismatch: 6, identity: 0.793

taagaccaggaacaccatcagctccagcc	CRISPR spacer
cacatccaggaacaccatcagccccaggc	Protospacer
.* . *****************.**** *

224. spacer 3.24|614218|29|NC_008312|CRT matches to NZ_CP022762 (Ralstonia solanacearum strain T95 plasmid unnamed, complete sequence) position: , mismatch: 6, identity: 0.793

taagaccaggaacaccatcagctccagcc	CRISPR spacer
cacatccaggaacaccatcagccccaggc	Protospacer
.* . *****************.**** *

225. spacer 3.24|614218|29|NC_008312|CRT matches to NZ_CP023017 (Ralstonia solanacearum strain SL3022 plasmid unnamed, complete sequence) position: , mismatch: 6, identity: 0.793

taagaccaggaacaccatcagctccagcc	CRISPR spacer
cacatccaggaacaccatcagccccaggc	Protospacer
.* . *****************.**** *

226. spacer 3.24|614218|29|NC_008312|CRT matches to NZ_CP014703 (Ralstonia solanacearum strain KACC 10722 plasmid, complete sequence) position: , mismatch: 6, identity: 0.793

taagaccaggaacaccatcagctccagcc	CRISPR spacer
cacatccaggaacaccatcagccccaggc	Protospacer
.* . *****************.**** *

227. spacer 3.24|614218|29|NC_008312|CRT matches to NZ_CP022760 (Ralstonia solanacearum strain T98 plasmid unnamed, complete sequence) position: , mismatch: 6, identity: 0.793

taagaccaggaacaccatcagctccagcc	CRISPR spacer
cacatccaggaacaccatcagccccaggc	Protospacer
.* . *****************.**** *

228. spacer 3.24|614218|29|NC_008312|CRT matches to NZ_CP022789 (Ralstonia solanacearum strain SL3175 plasmid unnamed, complete sequence) position: , mismatch: 6, identity: 0.793

taagaccaggaacaccatcagctccagcc	CRISPR spacer
cacatccaggaacaccatcagccccaggc	Protospacer
.* . *****************.**** *

229. spacer 3.24|614218|29|NC_008312|CRT matches to NZ_CP022771 (Ralstonia solanacearum strain T51 plasmid unnamed, complete sequence) position: , mismatch: 6, identity: 0.793

taagaccaggaacaccatcagctccagcc	CRISPR spacer
cacatccaggaacaccatcagccccaggc	Protospacer
.* . *****************.**** *

230. spacer 3.24|614218|29|NC_008312|CRT matches to NZ_CP022777 (Ralstonia solanacearum strain T11 plasmid unnamed, complete sequence) position: , mismatch: 6, identity: 0.793

taagaccaggaacaccatcagctccagcc	CRISPR spacer
cacatccaggaacaccatcagccccaggc	Protospacer
.* . *****************.**** *

231. spacer 3.24|614218|29|NC_008312|CRT matches to NZ_CP022799 (Ralstonia solanacearum strain SL2064 plasmid unnamed, complete sequence) position: , mismatch: 6, identity: 0.793

taagaccaggaacaccatcagctccagcc	CRISPR spacer
cacatccaggaacaccatcagccccaggc	Protospacer
.* . *****************.**** *

232. spacer 3.24|614218|29|NC_008312|CRT matches to NZ_CP022764 (Ralstonia solanacearum strain T82 plasmid unnamed, complete sequence) position: , mismatch: 6, identity: 0.793

taagaccaggaacaccatcagctccagcc	CRISPR spacer
cacatccaggaacaccatcagccccaggc	Protospacer
.* . *****************.**** *

233. spacer 3.24|614218|29|NC_008312|CRT matches to NZ_CP022797 (Ralstonia solanacearum strain SL2312 plasmid unnamed, complete sequence) position: , mismatch: 6, identity: 0.793

taagaccaggaacaccatcagctccagcc	CRISPR spacer
cacatccaggaacaccatcagccccaggc	Protospacer
.* . *****************.**** *

234. spacer 3.24|614218|29|NC_008312|CRT matches to NZ_CP022758 (Ralstonia solanacearum strain T101 plasmid unnamed, complete sequence) position: , mismatch: 6, identity: 0.793

taagaccaggaacaccatcagctccagcc	CRISPR spacer
cacatccaggaacaccatcagccccaggc	Protospacer
.* . *****************.**** *

235. spacer 3.24|614218|29|NC_008312|CRT matches to NZ_CP033220 (Parasedimentitalea marina strain W43 plasmid pW43A, complete sequence) position: , mismatch: 6, identity: 0.793

taagaccaggaacaccatcagctccagcc	CRISPR spacer
gatgaccacgaccaccatcagctccaaca	Protospacer
 * ***** ** **************.* 

236. spacer 3.24|614218|29|NC_008312|CRT matches to NZ_CP033220 (Parasedimentitalea marina strain W43 plasmid pW43A, complete sequence) position: , mismatch: 6, identity: 0.793

taagaccaggaacaccatcagctccagcc	CRISPR spacer
gatgaccacgaccaccatcagctccaaca	Protospacer
 * ***** ** **************.* 

237. spacer 3.29|614479|29|NC_008312|CRT matches to NZ_CP012940 (Ralstonia solanacearum strain UW163 plasmid unnamed, complete sequence) position: , mismatch: 6, identity: 0.793

taagaccaggaacaccatcagctccagct	CRISPR spacer
cacgtccaggaacaccatcagccccaggc	Protospacer
.* * *****************.**** .

238. spacer 3.29|614479|29|NC_008312|CRT matches to NZ_CP012944 (Ralstonia solanacearum strain IBSBF1503 plasmid unnamed, complete sequence) position: , mismatch: 6, identity: 0.793

taagaccaggaacaccatcagctccagct	CRISPR spacer
cacgtccaggaacaccatcagccccaggc	Protospacer
.* * *****************.**** .

239. spacer 3.29|614479|29|NC_008312|CRT matches to NZ_CP051295 (Ralstonia solanacearum strain CIAT_078 plasmid megaplasmid, complete sequence) position: , mismatch: 6, identity: 0.793

taagaccaggaacaccatcagctccagct	CRISPR spacer
cacgtccaggaacaccatcagccccaggc	Protospacer
.* * *****************.**** .

240. spacer 3.29|614479|29|NC_008312|CRT matches to NZ_CP026091 (Ralstonia solanacearum strain IBSBF 2570 plasmid unnamed, complete sequence) position: , mismatch: 6, identity: 0.793

taagaccaggaacaccatcagctccagct	CRISPR spacer
cacgtccaggaacaccatcagccccaggc	Protospacer
.* * *****************.**** .

241. spacer 3.29|614479|29|NC_008312|CRT matches to NC_014309 (Ralstonia solanacearum CFBP2957 plasmid RCFBPv3_mp, complete genome) position: , mismatch: 6, identity: 0.793

taagaccaggaacaccatcagctccagct	CRISPR spacer
cacgtccaggaacaccatcagccccaggc	Protospacer
.* * *****************.**** .

242. spacer 3.29|614479|29|NC_008312|CRT matches to NZ_CP021653 (Ralstonia solanacearum strain RS 488 plasmid unnamed, complete sequence) position: , mismatch: 6, identity: 0.793

taagaccaggaacaccatcagctccagct	CRISPR spacer
cacgtccaggaacaccatcagccccaggc	Protospacer
.* * *****************.**** .

243. spacer 3.29|614479|29|NC_008312|CRT matches to NZ_CP026093 (Ralstonia solanacearum strain SFC plasmid unnamed, complete sequence) position: , mismatch: 6, identity: 0.793

taagaccaggaacaccatcagctccagct	CRISPR spacer
cacgtccaggaacaccatcagccccaggc	Protospacer
.* * *****************.**** .

244. spacer 3.29|614479|29|NC_008312|CRT matches to NZ_CP021767 (Ralstonia solanacearum strain RS 489 plasmid unnamed, complete sequence) position: , mismatch: 6, identity: 0.793

taagaccaggaacaccatcagctccagct	CRISPR spacer
cacgtccaggaacaccatcagccccaggc	Protospacer
.* * *****************.**** .

245. spacer 3.29|614479|29|NC_008312|CRT matches to NZ_CP012688 (Ralstonia solanacearum strain UY031 plasmid unnamed, complete sequence) position: , mismatch: 6, identity: 0.793

taagaccaggaacaccatcagctccagct	CRISPR spacer
cacgtccaggaacaccatcagccccaggc	Protospacer
.* * *****************.**** .

246. spacer 3.29|614479|29|NC_008312|CRT matches to NC_017575 (Ralstonia solanacearum Po82 megaplasmid, complete sequence) position: , mismatch: 6, identity: 0.793

taagaccaggaacaccatcagctccagct	CRISPR spacer
cacgtccaggaacaccatcagccccaggc	Protospacer
.* * *****************.**** .

247. spacer 3.29|614479|29|NC_008312|CRT matches to NZ_CP026308 (Ralstonia solanacearum strain IBSBF 2571 plasmid unnamed, complete sequence) position: , mismatch: 6, identity: 0.793

taagaccaggaacaccatcagctccagct	CRISPR spacer
cacgtccaggaacaccatcagccccaggc	Protospacer
.* * *****************.**** .

248. spacer 3.29|614479|29|NC_008312|CRT matches to NZ_CP021765 (Ralstonia pseudosolanacearum strain CRMRs218 plasmid unnamed, complete sequence) position: , mismatch: 6, identity: 0.793

taagaccaggaacaccatcagctccagct	CRISPR spacer
cacgtccaggaacaccatcagccccaggc	Protospacer
.* * *****************.**** .

249. spacer 3.29|614479|29|NC_008312|CRT matches to CP047139 (Ralstonia solanacearum strain CFBP 8695 plasmid unnamed, complete sequence) position: , mismatch: 6, identity: 0.793

taagaccaggaacaccatcagctccagct	CRISPR spacer
cacgtccaggaacaccatcagccccaggc	Protospacer
.* * *****************.**** .

250. spacer 3.29|614479|29|NC_008312|CRT matches to CP047137 (Ralstonia solanacearum strain CFBP 8697 plasmid unnamed, complete sequence) position: , mismatch: 6, identity: 0.793

taagaccaggaacaccatcagctccagct	CRISPR spacer
cacgtccaggaacaccatcagccccaggc	Protospacer
.* * *****************.**** .

251. spacer 3.29|614479|29|NC_008312|CRT matches to NZ_CP033220 (Parasedimentitalea marina strain W43 plasmid pW43A, complete sequence) position: , mismatch: 6, identity: 0.793

taagaccaggaacaccatcagctccagct	CRISPR spacer
gatgaccacgaccaccatcagctccaaca	Protospacer
 * ***** ** **************.* 

252. spacer 3.29|614479|29|NC_008312|CRT matches to NZ_CP033220 (Parasedimentitalea marina strain W43 plasmid pW43A, complete sequence) position: , mismatch: 6, identity: 0.793

taagaccaggaacaccatcagctccagct	CRISPR spacer
gatgaccacgaccaccatcagctccaaca	Protospacer
 * ***** ** **************.* 

253. spacer 3.29|614479|29|NC_008312|CRT matches to NC_009128 (Corynebacterium sp. L2-79-05 plasmid pLEW279a, complete sequence) position: , mismatch: 6, identity: 0.793

taagaccaggaacaccatcagctccagct	CRISPR spacer
cgaaaccaggaacaccatctgctcctggt	Protospacer
..*.*************** ***** * *

254. spacer 3.29|614479|29|NC_008312|CRT matches to NZ_CP004352 (Corynebacterium casei LMG S-19264 plasmid pCASE2, complete sequence) position: , mismatch: 6, identity: 0.793

taagaccaggaacaccatcagctccagct	CRISPR spacer
cgaaaccaggaacaccatctgctcctggt	Protospacer
..*.*************** ***** * *

255. spacer 3.33|614713|29|NC_008312|CRT matches to NC_007501 (Lactobacillus phage Lc-Nu, complete genome) position: , mismatch: 6, identity: 0.793

taagaccaggaacaccatcagctccagcc	CRISPR spacer
ttgcaccaggaacaccatcagcaccatct	Protospacer
* . ****************** *** *.

256. spacer 3.33|614713|29|NC_008312|CRT matches to AY131267 (Bacteriophage Lc-Nu, complete genome) position: , mismatch: 6, identity: 0.793

taagaccaggaacaccatcagctccagcc	CRISPR spacer
ttgcaccaggaacaccatcagcaccatct	Protospacer
* . ****************** *** *.

257. spacer 3.33|614713|29|NC_008312|CRT matches to NZ_CP022775 (Ralstonia solanacearum strain T12 plasmid unnamed, complete sequence) position: , mismatch: 6, identity: 0.793

taagaccaggaacaccatcagctccagcc	CRISPR spacer
cacatccaggaacaccatcagccccaggc	Protospacer
.* . *****************.**** *

258. spacer 3.33|614713|29|NC_008312|CRT matches to NC_014310 (Ralstonia solanacearum PSI07 plasmid mpPSI07, complete sequence) position: , mismatch: 6, identity: 0.793

taagaccaggaacaccatcagctccagcc	CRISPR spacer
cacatccaggaacaccatcagccccaggc	Protospacer
.* . *****************.**** *

259. spacer 3.33|614713|29|NC_008312|CRT matches to NZ_CP022762 (Ralstonia solanacearum strain T95 plasmid unnamed, complete sequence) position: , mismatch: 6, identity: 0.793

taagaccaggaacaccatcagctccagcc	CRISPR spacer
cacatccaggaacaccatcagccccaggc	Protospacer
.* . *****************.**** *

260. spacer 3.33|614713|29|NC_008312|CRT matches to NZ_CP023017 (Ralstonia solanacearum strain SL3022 plasmid unnamed, complete sequence) position: , mismatch: 6, identity: 0.793

taagaccaggaacaccatcagctccagcc	CRISPR spacer
cacatccaggaacaccatcagccccaggc	Protospacer
.* . *****************.**** *

261. spacer 3.33|614713|29|NC_008312|CRT matches to NZ_CP014703 (Ralstonia solanacearum strain KACC 10722 plasmid, complete sequence) position: , mismatch: 6, identity: 0.793

taagaccaggaacaccatcagctccagcc	CRISPR spacer
cacatccaggaacaccatcagccccaggc	Protospacer
.* . *****************.**** *

262. spacer 3.33|614713|29|NC_008312|CRT matches to NZ_CP022760 (Ralstonia solanacearum strain T98 plasmid unnamed, complete sequence) position: , mismatch: 6, identity: 0.793

taagaccaggaacaccatcagctccagcc	CRISPR spacer
cacatccaggaacaccatcagccccaggc	Protospacer
.* . *****************.**** *

263. spacer 3.33|614713|29|NC_008312|CRT matches to NZ_CP022789 (Ralstonia solanacearum strain SL3175 plasmid unnamed, complete sequence) position: , mismatch: 6, identity: 0.793

taagaccaggaacaccatcagctccagcc	CRISPR spacer
cacatccaggaacaccatcagccccaggc	Protospacer
.* . *****************.**** *

264. spacer 3.33|614713|29|NC_008312|CRT matches to NZ_CP022771 (Ralstonia solanacearum strain T51 plasmid unnamed, complete sequence) position: , mismatch: 6, identity: 0.793

taagaccaggaacaccatcagctccagcc	CRISPR spacer
cacatccaggaacaccatcagccccaggc	Protospacer
.* . *****************.**** *

265. spacer 3.33|614713|29|NC_008312|CRT matches to NZ_CP022777 (Ralstonia solanacearum strain T11 plasmid unnamed, complete sequence) position: , mismatch: 6, identity: 0.793

taagaccaggaacaccatcagctccagcc	CRISPR spacer
cacatccaggaacaccatcagccccaggc	Protospacer
.* . *****************.**** *

266. spacer 3.33|614713|29|NC_008312|CRT matches to NZ_CP022799 (Ralstonia solanacearum strain SL2064 plasmid unnamed, complete sequence) position: , mismatch: 6, identity: 0.793

taagaccaggaacaccatcagctccagcc	CRISPR spacer
cacatccaggaacaccatcagccccaggc	Protospacer
.* . *****************.**** *

267. spacer 3.33|614713|29|NC_008312|CRT matches to NZ_CP022764 (Ralstonia solanacearum strain T82 plasmid unnamed, complete sequence) position: , mismatch: 6, identity: 0.793

taagaccaggaacaccatcagctccagcc	CRISPR spacer
cacatccaggaacaccatcagccccaggc	Protospacer
.* . *****************.**** *

268. spacer 3.33|614713|29|NC_008312|CRT matches to NZ_CP022797 (Ralstonia solanacearum strain SL2312 plasmid unnamed, complete sequence) position: , mismatch: 6, identity: 0.793

taagaccaggaacaccatcagctccagcc	CRISPR spacer
cacatccaggaacaccatcagccccaggc	Protospacer
.* . *****************.**** *

269. spacer 3.33|614713|29|NC_008312|CRT matches to NZ_CP022758 (Ralstonia solanacearum strain T101 plasmid unnamed, complete sequence) position: , mismatch: 6, identity: 0.793

taagaccaggaacaccatcagctccagcc	CRISPR spacer
cacatccaggaacaccatcagccccaggc	Protospacer
.* . *****************.**** *

270. spacer 3.33|614713|29|NC_008312|CRT matches to NZ_CP033220 (Parasedimentitalea marina strain W43 plasmid pW43A, complete sequence) position: , mismatch: 6, identity: 0.793

taagaccaggaacaccatcagctccagcc	CRISPR spacer
gatgaccacgaccaccatcagctccaaca	Protospacer
 * ***** ** **************.* 

271. spacer 3.33|614713|29|NC_008312|CRT matches to NZ_CP033220 (Parasedimentitalea marina strain W43 plasmid pW43A, complete sequence) position: , mismatch: 6, identity: 0.793

taagaccaggaacaccatcagctccagcc	CRISPR spacer
gatgaccacgaccaccatcagctccaaca	Protospacer
 * ***** ** **************.* 

272. spacer 3.35|614830|29|NC_008312|CRT matches to NC_007501 (Lactobacillus phage Lc-Nu, complete genome) position: , mismatch: 6, identity: 0.793

caagaccaggaacaccatcagctccagct	CRISPR spacer
ttgcaccaggaacaccatcagcaccatct	Protospacer
. . ****************** *** **

273. spacer 3.35|614830|29|NC_008312|CRT matches to AY131267 (Bacteriophage Lc-Nu, complete genome) position: , mismatch: 6, identity: 0.793

caagaccaggaacaccatcagctccagct	CRISPR spacer
ttgcaccaggaacaccatcagcaccatct	Protospacer
. . ****************** *** **

274. spacer 3.35|614830|29|NC_008312|CRT matches to NZ_CP022775 (Ralstonia solanacearum strain T12 plasmid unnamed, complete sequence) position: , mismatch: 6, identity: 0.793

caagaccaggaacaccatcagctccagct	CRISPR spacer
cacatccaggaacaccatcagccccaggc	Protospacer
** . *****************.**** .

275. spacer 3.35|614830|29|NC_008312|CRT matches to NC_014310 (Ralstonia solanacearum PSI07 plasmid mpPSI07, complete sequence) position: , mismatch: 6, identity: 0.793

caagaccaggaacaccatcagctccagct	CRISPR spacer
cacatccaggaacaccatcagccccaggc	Protospacer
** . *****************.**** .

276. spacer 3.35|614830|29|NC_008312|CRT matches to NZ_CP022762 (Ralstonia solanacearum strain T95 plasmid unnamed, complete sequence) position: , mismatch: 6, identity: 0.793

caagaccaggaacaccatcagctccagct	CRISPR spacer
cacatccaggaacaccatcagccccaggc	Protospacer
** . *****************.**** .

277. spacer 3.35|614830|29|NC_008312|CRT matches to NZ_CP023017 (Ralstonia solanacearum strain SL3022 plasmid unnamed, complete sequence) position: , mismatch: 6, identity: 0.793

caagaccaggaacaccatcagctccagct	CRISPR spacer
cacatccaggaacaccatcagccccaggc	Protospacer
** . *****************.**** .

278. spacer 3.35|614830|29|NC_008312|CRT matches to NZ_CP014703 (Ralstonia solanacearum strain KACC 10722 plasmid, complete sequence) position: , mismatch: 6, identity: 0.793

caagaccaggaacaccatcagctccagct	CRISPR spacer
cacatccaggaacaccatcagccccaggc	Protospacer
** . *****************.**** .

279. spacer 3.35|614830|29|NC_008312|CRT matches to NZ_CP022760 (Ralstonia solanacearum strain T98 plasmid unnamed, complete sequence) position: , mismatch: 6, identity: 0.793

caagaccaggaacaccatcagctccagct	CRISPR spacer
cacatccaggaacaccatcagccccaggc	Protospacer
** . *****************.**** .

280. spacer 3.35|614830|29|NC_008312|CRT matches to NZ_CP022789 (Ralstonia solanacearum strain SL3175 plasmid unnamed, complete sequence) position: , mismatch: 6, identity: 0.793

caagaccaggaacaccatcagctccagct	CRISPR spacer
cacatccaggaacaccatcagccccaggc	Protospacer
** . *****************.**** .

281. spacer 3.35|614830|29|NC_008312|CRT matches to NZ_CP022771 (Ralstonia solanacearum strain T51 plasmid unnamed, complete sequence) position: , mismatch: 6, identity: 0.793

caagaccaggaacaccatcagctccagct	CRISPR spacer
cacatccaggaacaccatcagccccaggc	Protospacer
** . *****************.**** .

282. spacer 3.35|614830|29|NC_008312|CRT matches to NZ_CP022777 (Ralstonia solanacearum strain T11 plasmid unnamed, complete sequence) position: , mismatch: 6, identity: 0.793

caagaccaggaacaccatcagctccagct	CRISPR spacer
cacatccaggaacaccatcagccccaggc	Protospacer
** . *****************.**** .

283. spacer 3.35|614830|29|NC_008312|CRT matches to NZ_CP022799 (Ralstonia solanacearum strain SL2064 plasmid unnamed, complete sequence) position: , mismatch: 6, identity: 0.793

caagaccaggaacaccatcagctccagct	CRISPR spacer
cacatccaggaacaccatcagccccaggc	Protospacer
** . *****************.**** .

284. spacer 3.35|614830|29|NC_008312|CRT matches to NZ_CP022764 (Ralstonia solanacearum strain T82 plasmid unnamed, complete sequence) position: , mismatch: 6, identity: 0.793

caagaccaggaacaccatcagctccagct	CRISPR spacer
cacatccaggaacaccatcagccccaggc	Protospacer
** . *****************.**** .

285. spacer 3.35|614830|29|NC_008312|CRT matches to NZ_CP022797 (Ralstonia solanacearum strain SL2312 plasmid unnamed, complete sequence) position: , mismatch: 6, identity: 0.793

caagaccaggaacaccatcagctccagct	CRISPR spacer
cacatccaggaacaccatcagccccaggc	Protospacer
** . *****************.**** .

286. spacer 3.35|614830|29|NC_008312|CRT matches to NZ_CP022758 (Ralstonia solanacearum strain T101 plasmid unnamed, complete sequence) position: , mismatch: 6, identity: 0.793

caagaccaggaacaccatcagctccagct	CRISPR spacer
cacatccaggaacaccatcagccccaggc	Protospacer
** . *****************.**** .

287. spacer 3.35|614830|29|NC_008312|CRT matches to NC_012654 (Clostridium botulinum Ba4 str. 657 plasmid pCLJ, complete sequence) position: , mismatch: 6, identity: 0.793

caagaccaggaacaccatcagctccagct	CRISPR spacer
cattgccaggaagaccatcagctccacca	Protospacer
**  .******* ************* * 

288. spacer 3.35|614830|29|NC_008312|CRT matches to NZ_CP034811 (Paracoccus sp. Arc7-R13 plasmid unnamed1, complete sequence) position: , mismatch: 6, identity: 0.793

caagaccaggaacaccatcagctccagct	CRISPR spacer
cagttccaggaacacgatcagcgccagcg	Protospacer
**.  ********** ****** ***** 

289. spacer 3.35|614830|29|NC_008312|CRT matches to NC_028835 (Lactobacillus phage CL2, complete genome) position: , mismatch: 6, identity: 0.793

caagaccaggaacaccatcagctccagct	CRISPR spacer
taggaccgggaacaccatcagcaccatca	Protospacer
.*.****.************** *** * 

290. spacer 3.35|614830|29|NC_008312|CRT matches to KR905066 (Lactobacillus phage CL1, complete genome) position: , mismatch: 6, identity: 0.793

caagaccaggaacaccatcagctccagct	CRISPR spacer
taggaccgggaacaccatcagcaccatca	Protospacer
.*.****.************** *** * 

291. spacer 3.35|614830|29|NC_008312|CRT matches to NC_028911 (Lactobacillus phage iLp1308, complete genome) position: , mismatch: 6, identity: 0.793

caagaccaggaacaccatcagctccagct	CRISPR spacer
taggaccgggaacaccatcagcaccatca	Protospacer
.*.****.************** *** * 

292. spacer 3.35|614830|29|NC_008312|CRT matches to NZ_CP033220 (Parasedimentitalea marina strain W43 plasmid pW43A, complete sequence) position: , mismatch: 6, identity: 0.793

caagaccaggaacaccatcagctccagct	CRISPR spacer
gatgaccacgaccaccatcagctccaaca	Protospacer
 * ***** ** **************.* 

293. spacer 3.35|614830|29|NC_008312|CRT matches to NZ_CP033220 (Parasedimentitalea marina strain W43 plasmid pW43A, complete sequence) position: , mismatch: 6, identity: 0.793

caagaccaggaacaccatcagctccagct	CRISPR spacer
gatgaccacgaccaccatcagctccaaca	Protospacer
 * ***** ** **************.* 

294. spacer 3.35|614830|29|NC_008312|CRT matches to NZ_CP006909 (Clostridium botulinum CDC_1436 plasmid pCBG, complete sequence) position: , mismatch: 6, identity: 0.793

caagaccaggaacaccatcagctccagct	CRISPR spacer
cattgccaggaagaccatcagctccacca	Protospacer
**  .******* ************* * 

295. spacer 3.35|614830|29|NC_008312|CRT matches to NZ_CP031095 (Clostridium botulinum strain CFSAN034200 plasmid p1_CDC51232, complete sequence) position: , mismatch: 6, identity: 0.793

caagaccaggaacaccatcagctccagct	CRISPR spacer
cattgccaggaagaccatcagctccacca	Protospacer
**  .******* ************* * 

296. spacer 3.40|615091|29|NC_008312|CRT matches to NZ_CP012940 (Ralstonia solanacearum strain UW163 plasmid unnamed, complete sequence) position: , mismatch: 6, identity: 0.793

taagaccaggaacaccatcagctccagct	CRISPR spacer
cacgtccaggaacaccatcagccccaggc	Protospacer
.* * *****************.**** .

297. spacer 3.40|615091|29|NC_008312|CRT matches to NZ_CP012944 (Ralstonia solanacearum strain IBSBF1503 plasmid unnamed, complete sequence) position: , mismatch: 6, identity: 0.793

taagaccaggaacaccatcagctccagct	CRISPR spacer
cacgtccaggaacaccatcagccccaggc	Protospacer
.* * *****************.**** .

298. spacer 3.40|615091|29|NC_008312|CRT matches to NZ_CP051295 (Ralstonia solanacearum strain CIAT_078 plasmid megaplasmid, complete sequence) position: , mismatch: 6, identity: 0.793

taagaccaggaacaccatcagctccagct	CRISPR spacer
cacgtccaggaacaccatcagccccaggc	Protospacer
.* * *****************.**** .

299. spacer 3.40|615091|29|NC_008312|CRT matches to NZ_CP026091 (Ralstonia solanacearum strain IBSBF 2570 plasmid unnamed, complete sequence) position: , mismatch: 6, identity: 0.793

taagaccaggaacaccatcagctccagct	CRISPR spacer
cacgtccaggaacaccatcagccccaggc	Protospacer
.* * *****************.**** .

300. spacer 3.40|615091|29|NC_008312|CRT matches to NC_014309 (Ralstonia solanacearum CFBP2957 plasmid RCFBPv3_mp, complete genome) position: , mismatch: 6, identity: 0.793

taagaccaggaacaccatcagctccagct	CRISPR spacer
cacgtccaggaacaccatcagccccaggc	Protospacer
.* * *****************.**** .

301. spacer 3.40|615091|29|NC_008312|CRT matches to NZ_CP021653 (Ralstonia solanacearum strain RS 488 plasmid unnamed, complete sequence) position: , mismatch: 6, identity: 0.793

taagaccaggaacaccatcagctccagct	CRISPR spacer
cacgtccaggaacaccatcagccccaggc	Protospacer
.* * *****************.**** .

302. spacer 3.40|615091|29|NC_008312|CRT matches to NZ_CP026093 (Ralstonia solanacearum strain SFC plasmid unnamed, complete sequence) position: , mismatch: 6, identity: 0.793

taagaccaggaacaccatcagctccagct	CRISPR spacer
cacgtccaggaacaccatcagccccaggc	Protospacer
.* * *****************.**** .

303. spacer 3.40|615091|29|NC_008312|CRT matches to NZ_CP021767 (Ralstonia solanacearum strain RS 489 plasmid unnamed, complete sequence) position: , mismatch: 6, identity: 0.793

taagaccaggaacaccatcagctccagct	CRISPR spacer
cacgtccaggaacaccatcagccccaggc	Protospacer
.* * *****************.**** .

304. spacer 3.40|615091|29|NC_008312|CRT matches to NZ_CP012688 (Ralstonia solanacearum strain UY031 plasmid unnamed, complete sequence) position: , mismatch: 6, identity: 0.793

taagaccaggaacaccatcagctccagct	CRISPR spacer
cacgtccaggaacaccatcagccccaggc	Protospacer
.* * *****************.**** .

305. spacer 3.40|615091|29|NC_008312|CRT matches to NC_017575 (Ralstonia solanacearum Po82 megaplasmid, complete sequence) position: , mismatch: 6, identity: 0.793

taagaccaggaacaccatcagctccagct	CRISPR spacer
cacgtccaggaacaccatcagccccaggc	Protospacer
.* * *****************.**** .

306. spacer 3.40|615091|29|NC_008312|CRT matches to NZ_CP026308 (Ralstonia solanacearum strain IBSBF 2571 plasmid unnamed, complete sequence) position: , mismatch: 6, identity: 0.793

taagaccaggaacaccatcagctccagct	CRISPR spacer
cacgtccaggaacaccatcagccccaggc	Protospacer
.* * *****************.**** .

307. spacer 3.40|615091|29|NC_008312|CRT matches to NZ_CP021765 (Ralstonia pseudosolanacearum strain CRMRs218 plasmid unnamed, complete sequence) position: , mismatch: 6, identity: 0.793

taagaccaggaacaccatcagctccagct	CRISPR spacer
cacgtccaggaacaccatcagccccaggc	Protospacer
.* * *****************.**** .

308. spacer 3.40|615091|29|NC_008312|CRT matches to CP047139 (Ralstonia solanacearum strain CFBP 8695 plasmid unnamed, complete sequence) position: , mismatch: 6, identity: 0.793

taagaccaggaacaccatcagctccagct	CRISPR spacer
cacgtccaggaacaccatcagccccaggc	Protospacer
.* * *****************.**** .

309. spacer 3.40|615091|29|NC_008312|CRT matches to CP047137 (Ralstonia solanacearum strain CFBP 8697 plasmid unnamed, complete sequence) position: , mismatch: 6, identity: 0.793

taagaccaggaacaccatcagctccagct	CRISPR spacer
cacgtccaggaacaccatcagccccaggc	Protospacer
.* * *****************.**** .

310. spacer 3.40|615091|29|NC_008312|CRT matches to NZ_CP033220 (Parasedimentitalea marina strain W43 plasmid pW43A, complete sequence) position: , mismatch: 6, identity: 0.793

taagaccaggaacaccatcagctccagct	CRISPR spacer
gatgaccacgaccaccatcagctccaaca	Protospacer
 * ***** ** **************.* 

311. spacer 3.40|615091|29|NC_008312|CRT matches to NZ_CP033220 (Parasedimentitalea marina strain W43 plasmid pW43A, complete sequence) position: , mismatch: 6, identity: 0.793

taagaccaggaacaccatcagctccagct	CRISPR spacer
gatgaccacgaccaccatcagctccaaca	Protospacer
 * ***** ** **************.* 

312. spacer 3.40|615091|29|NC_008312|CRT matches to NC_009128 (Corynebacterium sp. L2-79-05 plasmid pLEW279a, complete sequence) position: , mismatch: 6, identity: 0.793

taagaccaggaacaccatcagctccagct	CRISPR spacer
cgaaaccaggaacaccatctgctcctggt	Protospacer
..*.*************** ***** * *

313. spacer 3.40|615091|29|NC_008312|CRT matches to NZ_CP004352 (Corynebacterium casei LMG S-19264 plasmid pCASE2, complete sequence) position: , mismatch: 6, identity: 0.793

taagaccaggaacaccatcagctccagct	CRISPR spacer
cgaaaccaggaacaccatctgctcctggt	Protospacer
..*.*************** ***** * *

314. spacer 3.45|615433|29|NC_008312|CRT matches to NC_007501 (Lactobacillus phage Lc-Nu, complete genome) position: , mismatch: 6, identity: 0.793

caagaccaggaacaccatcagctccagct	CRISPR spacer
ttgcaccaggaacaccatcagcaccatct	Protospacer
. . ****************** *** **

315. spacer 3.45|615433|29|NC_008312|CRT matches to AY131267 (Bacteriophage Lc-Nu, complete genome) position: , mismatch: 6, identity: 0.793

caagaccaggaacaccatcagctccagct	CRISPR spacer
ttgcaccaggaacaccatcagcaccatct	Protospacer
. . ****************** *** **

316. spacer 3.45|615433|29|NC_008312|CRT matches to NZ_CP022775 (Ralstonia solanacearum strain T12 plasmid unnamed, complete sequence) position: , mismatch: 6, identity: 0.793

caagaccaggaacaccatcagctccagct	CRISPR spacer
cacatccaggaacaccatcagccccaggc	Protospacer
** . *****************.**** .

317. spacer 3.45|615433|29|NC_008312|CRT matches to NC_014310 (Ralstonia solanacearum PSI07 plasmid mpPSI07, complete sequence) position: , mismatch: 6, identity: 0.793

caagaccaggaacaccatcagctccagct	CRISPR spacer
cacatccaggaacaccatcagccccaggc	Protospacer
** . *****************.**** .

318. spacer 3.45|615433|29|NC_008312|CRT matches to NZ_CP022762 (Ralstonia solanacearum strain T95 plasmid unnamed, complete sequence) position: , mismatch: 6, identity: 0.793

caagaccaggaacaccatcagctccagct	CRISPR spacer
cacatccaggaacaccatcagccccaggc	Protospacer
** . *****************.**** .

319. spacer 3.45|615433|29|NC_008312|CRT matches to NZ_CP023017 (Ralstonia solanacearum strain SL3022 plasmid unnamed, complete sequence) position: , mismatch: 6, identity: 0.793

caagaccaggaacaccatcagctccagct	CRISPR spacer
cacatccaggaacaccatcagccccaggc	Protospacer
** . *****************.**** .

320. spacer 3.45|615433|29|NC_008312|CRT matches to NZ_CP014703 (Ralstonia solanacearum strain KACC 10722 plasmid, complete sequence) position: , mismatch: 6, identity: 0.793

caagaccaggaacaccatcagctccagct	CRISPR spacer
cacatccaggaacaccatcagccccaggc	Protospacer
** . *****************.**** .

321. spacer 3.45|615433|29|NC_008312|CRT matches to NZ_CP022760 (Ralstonia solanacearum strain T98 plasmid unnamed, complete sequence) position: , mismatch: 6, identity: 0.793

caagaccaggaacaccatcagctccagct	CRISPR spacer
cacatccaggaacaccatcagccccaggc	Protospacer
** . *****************.**** .

322. spacer 3.45|615433|29|NC_008312|CRT matches to NZ_CP022789 (Ralstonia solanacearum strain SL3175 plasmid unnamed, complete sequence) position: , mismatch: 6, identity: 0.793

caagaccaggaacaccatcagctccagct	CRISPR spacer
cacatccaggaacaccatcagccccaggc	Protospacer
** . *****************.**** .

323. spacer 3.45|615433|29|NC_008312|CRT matches to NZ_CP022771 (Ralstonia solanacearum strain T51 plasmid unnamed, complete sequence) position: , mismatch: 6, identity: 0.793

caagaccaggaacaccatcagctccagct	CRISPR spacer
cacatccaggaacaccatcagccccaggc	Protospacer
** . *****************.**** .

324. spacer 3.45|615433|29|NC_008312|CRT matches to NZ_CP022777 (Ralstonia solanacearum strain T11 plasmid unnamed, complete sequence) position: , mismatch: 6, identity: 0.793

caagaccaggaacaccatcagctccagct	CRISPR spacer
cacatccaggaacaccatcagccccaggc	Protospacer
** . *****************.**** .

325. spacer 3.45|615433|29|NC_008312|CRT matches to NZ_CP022799 (Ralstonia solanacearum strain SL2064 plasmid unnamed, complete sequence) position: , mismatch: 6, identity: 0.793

caagaccaggaacaccatcagctccagct	CRISPR spacer
cacatccaggaacaccatcagccccaggc	Protospacer
** . *****************.**** .

326. spacer 3.45|615433|29|NC_008312|CRT matches to NZ_CP022764 (Ralstonia solanacearum strain T82 plasmid unnamed, complete sequence) position: , mismatch: 6, identity: 0.793

caagaccaggaacaccatcagctccagct	CRISPR spacer
cacatccaggaacaccatcagccccaggc	Protospacer
** . *****************.**** .

327. spacer 3.45|615433|29|NC_008312|CRT matches to NZ_CP022797 (Ralstonia solanacearum strain SL2312 plasmid unnamed, complete sequence) position: , mismatch: 6, identity: 0.793

caagaccaggaacaccatcagctccagct	CRISPR spacer
cacatccaggaacaccatcagccccaggc	Protospacer
** . *****************.**** .

328. spacer 3.45|615433|29|NC_008312|CRT matches to NZ_CP022758 (Ralstonia solanacearum strain T101 plasmid unnamed, complete sequence) position: , mismatch: 6, identity: 0.793

caagaccaggaacaccatcagctccagct	CRISPR spacer
cacatccaggaacaccatcagccccaggc	Protospacer
** . *****************.**** .

329. spacer 3.45|615433|29|NC_008312|CRT matches to NC_012654 (Clostridium botulinum Ba4 str. 657 plasmid pCLJ, complete sequence) position: , mismatch: 6, identity: 0.793

caagaccaggaacaccatcagctccagct	CRISPR spacer
cattgccaggaagaccatcagctccacca	Protospacer
**  .******* ************* * 

330. spacer 3.45|615433|29|NC_008312|CRT matches to NZ_CP034811 (Paracoccus sp. Arc7-R13 plasmid unnamed1, complete sequence) position: , mismatch: 6, identity: 0.793

caagaccaggaacaccatcagctccagct	CRISPR spacer
cagttccaggaacacgatcagcgccagcg	Protospacer
**.  ********** ****** ***** 

331. spacer 3.45|615433|29|NC_008312|CRT matches to NC_028835 (Lactobacillus phage CL2, complete genome) position: , mismatch: 6, identity: 0.793

caagaccaggaacaccatcagctccagct	CRISPR spacer
taggaccgggaacaccatcagcaccatca	Protospacer
.*.****.************** *** * 

332. spacer 3.45|615433|29|NC_008312|CRT matches to KR905066 (Lactobacillus phage CL1, complete genome) position: , mismatch: 6, identity: 0.793

caagaccaggaacaccatcagctccagct	CRISPR spacer
taggaccgggaacaccatcagcaccatca	Protospacer
.*.****.************** *** * 

333. spacer 3.45|615433|29|NC_008312|CRT matches to NC_028911 (Lactobacillus phage iLp1308, complete genome) position: , mismatch: 6, identity: 0.793

caagaccaggaacaccatcagctccagct	CRISPR spacer
taggaccgggaacaccatcagcaccatca	Protospacer
.*.****.************** *** * 

334. spacer 3.45|615433|29|NC_008312|CRT matches to NZ_CP033220 (Parasedimentitalea marina strain W43 plasmid pW43A, complete sequence) position: , mismatch: 6, identity: 0.793

caagaccaggaacaccatcagctccagct	CRISPR spacer
gatgaccacgaccaccatcagctccaaca	Protospacer
 * ***** ** **************.* 

335. spacer 3.45|615433|29|NC_008312|CRT matches to NZ_CP033220 (Parasedimentitalea marina strain W43 plasmid pW43A, complete sequence) position: , mismatch: 6, identity: 0.793

caagaccaggaacaccatcagctccagct	CRISPR spacer
gatgaccacgaccaccatcagctccaaca	Protospacer
 * ***** ** **************.* 

336. spacer 3.45|615433|29|NC_008312|CRT matches to NZ_CP006909 (Clostridium botulinum CDC_1436 plasmid pCBG, complete sequence) position: , mismatch: 6, identity: 0.793

caagaccaggaacaccatcagctccagct	CRISPR spacer
cattgccaggaagaccatcagctccacca	Protospacer
**  .******* ************* * 

337. spacer 3.45|615433|29|NC_008312|CRT matches to NZ_CP031095 (Clostridium botulinum strain CFSAN034200 plasmid p1_CDC51232, complete sequence) position: , mismatch: 6, identity: 0.793

caagaccaggaacaccatcagctccagct	CRISPR spacer
cattgccaggaagaccatcagctccacca	Protospacer
**  .******* ************* * 

338. spacer 4.3|617317|29|NC_008312|CRT matches to NZ_CP033220 (Parasedimentitalea marina strain W43 plasmid pW43A, complete sequence) position: , mismatch: 6, identity: 0.793

caagaccaggaacaccatcagctccagcc	CRISPR spacer
gatgaccacgaccaccatcagctccaaca	Protospacer
 * ***** ** **************.* 

339. spacer 4.3|617317|29|NC_008312|CRT matches to NZ_CP033220 (Parasedimentitalea marina strain W43 plasmid pW43A, complete sequence) position: , mismatch: 6, identity: 0.793

caagaccaggaacaccatcagctccagcc	CRISPR spacer
gatgaccacgaccaccatcagctccaaca	Protospacer
 * ***** ** **************.* 

340. spacer 4.3|617317|29|NC_008312|CRT matches to NZ_CP006909 (Clostridium botulinum CDC_1436 plasmid pCBG, complete sequence) position: , mismatch: 6, identity: 0.793

caagaccaggaacaccatcagctccagcc	CRISPR spacer
cattgccaggaagaccatcagctccacca	Protospacer
**  .******* ************* * 

341. spacer 4.3|617317|29|NC_008312|CRT matches to NZ_CP031095 (Clostridium botulinum strain CFSAN034200 plasmid p1_CDC51232, complete sequence) position: , mismatch: 6, identity: 0.793

caagaccaggaacaccatcagctccagcc	CRISPR spacer
cattgccaggaagaccatcagctccacca	Protospacer
**  .******* ************* * 

342. spacer 4.3|617317|29|NC_008312|CRT matches to NC_009128 (Corynebacterium sp. L2-79-05 plasmid pLEW279a, complete sequence) position: , mismatch: 6, identity: 0.793

caagaccaggaacaccatcagctccagcc	CRISPR spacer
cgaaaccaggaacaccatctgctcctggt	Protospacer
*.*.*************** ***** * .

343. spacer 4.3|617317|29|NC_008312|CRT matches to NZ_CP004352 (Corynebacterium casei LMG S-19264 plasmid pCASE2, complete sequence) position: , mismatch: 6, identity: 0.793

caagaccaggaacaccatcagctccagcc	CRISPR spacer
cgaaaccaggaacaccatctgctcctggt	Protospacer
*.*.*************** ***** * .

344. spacer 4.3|617317|29|NC_008312|CRT matches to NC_012654 (Clostridium botulinum Ba4 str. 657 plasmid pCLJ, complete sequence) position: , mismatch: 6, identity: 0.793

caagaccaggaacaccatcagctccagcc	CRISPR spacer
cattgccaggaagaccatcagctccacca	Protospacer
**  .******* ************* * 

345. spacer 4.3|617317|29|NC_008312|CRT matches to NZ_CP034811 (Paracoccus sp. Arc7-R13 plasmid unnamed1, complete sequence) position: , mismatch: 6, identity: 0.793

caagaccaggaacaccatcagctccagcc	CRISPR spacer
cagttccaggaacacgatcagcgccagcg	Protospacer
**.  ********** ****** ***** 

346. spacer 4.3|617317|29|NC_008312|CRT matches to NC_028835 (Lactobacillus phage CL2, complete genome) position: , mismatch: 6, identity: 0.793

caagaccaggaacaccatcagctccagcc	CRISPR spacer
taggaccgggaacaccatcagcaccatca	Protospacer
.*.****.************** *** * 

347. spacer 4.3|617317|29|NC_008312|CRT matches to KR905066 (Lactobacillus phage CL1, complete genome) position: , mismatch: 6, identity: 0.793

caagaccaggaacaccatcagctccagcc	CRISPR spacer
taggaccgggaacaccatcagcaccatca	Protospacer
.*.****.************** *** * 

348. spacer 4.3|617317|29|NC_008312|CRT matches to NC_028911 (Lactobacillus phage iLp1308, complete genome) position: , mismatch: 6, identity: 0.793

caagaccaggaacaccatcagctccagcc	CRISPR spacer
taggaccgggaacaccatcagcaccatca	Protospacer
.*.****.************** *** * 

349. spacer 4.5|617434|29|NC_008312|CRT matches to NZ_CP033220 (Parasedimentitalea marina strain W43 plasmid pW43A, complete sequence) position: , mismatch: 6, identity: 0.793

caagaccaggaacaccatcagctccagcc	CRISPR spacer
gatgaccacgaccaccatcagctccaaca	Protospacer
 * ***** ** **************.* 

350. spacer 4.5|617434|29|NC_008312|CRT matches to NZ_CP033220 (Parasedimentitalea marina strain W43 plasmid pW43A, complete sequence) position: , mismatch: 6, identity: 0.793

caagaccaggaacaccatcagctccagcc	CRISPR spacer
gatgaccacgaccaccatcagctccaaca	Protospacer
 * ***** ** **************.* 

351. spacer 4.5|617434|29|NC_008312|CRT matches to NZ_CP006909 (Clostridium botulinum CDC_1436 plasmid pCBG, complete sequence) position: , mismatch: 6, identity: 0.793

caagaccaggaacaccatcagctccagcc	CRISPR spacer
cattgccaggaagaccatcagctccacca	Protospacer
**  .******* ************* * 

352. spacer 4.5|617434|29|NC_008312|CRT matches to NZ_CP031095 (Clostridium botulinum strain CFSAN034200 plasmid p1_CDC51232, complete sequence) position: , mismatch: 6, identity: 0.793

caagaccaggaacaccatcagctccagcc	CRISPR spacer
cattgccaggaagaccatcagctccacca	Protospacer
**  .******* ************* * 

353. spacer 4.5|617434|29|NC_008312|CRT matches to NC_009128 (Corynebacterium sp. L2-79-05 plasmid pLEW279a, complete sequence) position: , mismatch: 6, identity: 0.793

caagaccaggaacaccatcagctccagcc	CRISPR spacer
cgaaaccaggaacaccatctgctcctggt	Protospacer
*.*.*************** ***** * .

354. spacer 4.5|617434|29|NC_008312|CRT matches to NZ_CP004352 (Corynebacterium casei LMG S-19264 plasmid pCASE2, complete sequence) position: , mismatch: 6, identity: 0.793

caagaccaggaacaccatcagctccagcc	CRISPR spacer
cgaaaccaggaacaccatctgctcctggt	Protospacer
*.*.*************** ***** * .

355. spacer 4.5|617434|29|NC_008312|CRT matches to NC_012654 (Clostridium botulinum Ba4 str. 657 plasmid pCLJ, complete sequence) position: , mismatch: 6, identity: 0.793

caagaccaggaacaccatcagctccagcc	CRISPR spacer
cattgccaggaagaccatcagctccacca	Protospacer
**  .******* ************* * 

356. spacer 4.5|617434|29|NC_008312|CRT matches to NZ_CP034811 (Paracoccus sp. Arc7-R13 plasmid unnamed1, complete sequence) position: , mismatch: 6, identity: 0.793

caagaccaggaacaccatcagctccagcc	CRISPR spacer
cagttccaggaacacgatcagcgccagcg	Protospacer
**.  ********** ****** ***** 

357. spacer 4.5|617434|29|NC_008312|CRT matches to NC_028835 (Lactobacillus phage CL2, complete genome) position: , mismatch: 6, identity: 0.793

caagaccaggaacaccatcagctccagcc	CRISPR spacer
taggaccgggaacaccatcagcaccatca	Protospacer
.*.****.************** *** * 

358. spacer 4.5|617434|29|NC_008312|CRT matches to KR905066 (Lactobacillus phage CL1, complete genome) position: , mismatch: 6, identity: 0.793

caagaccaggaacaccatcagctccagcc	CRISPR spacer
taggaccgggaacaccatcagcaccatca	Protospacer
.*.****.************** *** * 

359. spacer 4.5|617434|29|NC_008312|CRT matches to NC_028911 (Lactobacillus phage iLp1308, complete genome) position: , mismatch: 6, identity: 0.793

caagaccaggaacaccatcagctccagcc	CRISPR spacer
taggaccgggaacaccatcagcaccatca	Protospacer
.*.****.************** *** * 

360. spacer 12.14|1607246|27|NC_008312|CRT matches to NZ_CP022182 (Aeromonas salmonicida strain S68 plasmid pS68-1, complete sequence) position: , mismatch: 6, identity: 0.778

tcaattattggcttttttagttatcag	CRISPR spacer
atcattgatggcttttttagttatcat	Protospacer
 . ***. ****************** 

361. spacer 12.14|1607246|27|NC_008312|CRT matches to NZ_CP022177 (Aeromonas salmonicida strain S44 plasmid pS44-2, complete sequence) position: , mismatch: 6, identity: 0.778

tcaattattggcttttttagttatcag	CRISPR spacer
atcattgatggcttttttagttatcat	Protospacer
 . ***. ****************** 

362. spacer 12.14|1607246|27|NC_008312|CRT matches to NZ_CP017144 (Aeromonas salmonicida subsp. masoucida strain RFAS1 plasmid unnamed1, complete sequence) position: , mismatch: 6, identity: 0.778

tcaattattggcttttttagttatcag	CRISPR spacer
atcattgatggcttttttagttatcat	Protospacer
 . ***. ****************** 

363. spacer 12.14|1607246|27|NC_008312|CRT matches to NZ_CP022171 (Aeromonas salmonicida strain S121 plasmid pS121-2, complete sequence) position: , mismatch: 6, identity: 0.778

tcaattattggcttttttagttatcag	CRISPR spacer
atcattgatggcttttttagttatcat	Protospacer
 . ***. ****************** 

364. spacer 17.1|1941253|35|NC_008312|CRISPRCasFinder matches to NC_028924 (Polaribacter phage P12002L, complete genome) position: , mismatch: 6, identity: 0.829

taatagttaaagcaagaaattataaagatttaatt	CRISPR spacer
caatgaataaagcaaaaaattataaaaatttaatt	Protospacer
.***.. ********.**********.********

365. spacer 17.1|1941253|35|NC_008312|CRISPRCasFinder matches to NC_028763 (Polaribacter phage P12002S, complete genome) position: , mismatch: 6, identity: 0.829

taatagttaaagcaagaaattataaagatttaatt	CRISPR spacer
caatgaataaagcaaaaaattataaaaatttaatt	Protospacer
.***.. ********.**********.********

366. spacer 21.19|2628169|26|NC_008312|CRT matches to MN693047 (Marine virus AFVG_25M111, complete genome) position: , mismatch: 6, identity: 0.769

tcatttttttgaggtgttaggtttta	CRISPR spacer
ccaattttttgaggtgttaggtgacc	Protospacer
.** ******************  . 

367. spacer 21.19|2628169|26|NC_008312|CRT matches to MN693506 (Marine virus AFVG_25M112, complete genome) position: , mismatch: 6, identity: 0.769

tcatttttttgaggtgttaggtttta	CRISPR spacer
ccaattttttgaggtgttaggtgacc	Protospacer
.** ******************  . 

368. spacer 21.21|2628250|26|NC_008312|CRT matches to MN693047 (Marine virus AFVG_25M111, complete genome) position: , mismatch: 6, identity: 0.769

tcatttttttgaggtgttaggtttta	CRISPR spacer
ccaattttttgaggtgttaggtgacc	Protospacer
.** ******************  . 

369. spacer 21.21|2628250|26|NC_008312|CRT matches to MN693506 (Marine virus AFVG_25M112, complete genome) position: , mismatch: 6, identity: 0.769

tcatttttttgaggtgttaggtttta	CRISPR spacer
ccaattttttgaggtgttaggtgacc	Protospacer
.** ******************  . 

370. spacer 21.32|2628710|26|NC_008312|CRT matches to KX119180 (Helicobacter phage Pt5303G hypothetical protein and putative transcriptional regulator protein genes, complete cds) position: , mismatch: 6, identity: 0.769

tcaattttttgaggttttaggtgtta	CRISPR spacer
atgttttttttaggttttaggtgttc	Protospacer
 .. ****** ************** 

371. spacer 21.51|2629736|40|NC_008312|CRT matches to NZ_CP015730 (Bacillus cereus strain A1 plasmid pBCA1, complete sequence) position: , mismatch: 6, identity: 0.85

ttaggttttaggttttaggttttaagtttgaggtctcatt	CRISPR spacer
ttaggttttaggttttaggttttaggttttaggttttagg	Protospacer
************************.**** ****.*.*  

372. spacer 21.51|2629736|40|NC_008312|CRT matches to NZ_CP015730 (Bacillus cereus strain A1 plasmid pBCA1, complete sequence) position: , mismatch: 6, identity: 0.85

ttaggttttaggttttaggttttaagtttgaggtctcatt	CRISPR spacer
ttaggttttaggttttaggttttaggttttaggtttgtta	Protospacer
************************.**** ****.*  * 

373. spacer 29.4|3671731|26|NC_008312|CRISPRCasFinder matches to KC465899 (Pelagibacter phage HTVC008M, complete genome) position: , mismatch: 6, identity: 0.769

aagcagaagttaatagtgcattatcc	CRISPR spacer
ttgcagaatttaatagtgcattacaa	Protospacer
  ****** **************.  

374. spacer 33.1|4206516|31|NC_008312|CRISPRCasFinder matches to KX229736 (Campylobacter phage PC5, complete genome) position: , mismatch: 6, identity: 0.806

--aagttgagctaataaataatctgctgatttt	CRISPR spacer
tgaaat--ggctaataaagaatgtgctgatttt	Protospacer
  **.*  .********* *** **********

375. spacer 33.1|4206516|31|NC_008312|CRISPRCasFinder matches to NC_015464 (Campylobacter phage NCTC12673, complete genome) position: , mismatch: 6, identity: 0.806

--aagttgagctaataaataatctgctgatttt	CRISPR spacer
tgaaat--ggctaataaagaatgtgctgatttt	Protospacer
  **.*  .********* *** **********

376. spacer 33.1|4206516|31|NC_008312|CRISPRCasFinder matches to KX236333 (Campylobacter phage PC14, complete genome) position: , mismatch: 6, identity: 0.806

--aagttgagctaataaataatctgctgatttt	CRISPR spacer
tgaaat--ggctaataaagaatgtgctgatttt	Protospacer
  **.*  .********* *** **********

377. spacer 33.1|4206516|31|NC_008312|CRISPRCasFinder matches to JX569801 (Campylobacter phage CP30A, complete genome) position: , mismatch: 6, identity: 0.806

--aagttgagctaataaataatctgctgatttt	CRISPR spacer
tgaaat--ggctaataaagaatgtgctgatttt	Protospacer
  **.*  .********* *** **********

378. spacer 45.6|6864734|30|NC_008312|CRT matches to NZ_CP016613 (Ralstonia solanacearum FJAT-91 plasmid unnamed1, complete sequence) position: , mismatch: 6, identity: 0.8

----acggcgtggcggttggcgtggcggttggcg	CRISPR spacer
atccacg----agcggttggcgtcgcggttggcg	Protospacer
    ***    .*********** **********

379. spacer 45.6|6864734|30|NC_008312|CRT matches to NZ_CP027115 (Gordonia alkanivorans strain YC-RL2 plasmid pYYC01, complete sequence) position: , mismatch: 6, identity: 0.8

acggcgtggcggttggcgtggcggttggcg	CRISPR spacer
cggtcctggcggttggcctggcgcttggcg	Protospacer
  * * *********** ***** ******

380. spacer 45.6|6864734|30|NC_008312|CRT matches to NZ_CP052069 (Ralstonia solanacearum strain FJAT91.F50 plasmid Plas1, complete sequence) position: , mismatch: 6, identity: 0.8

----acggcgtggcggttggcgtggcggttggcg	CRISPR spacer
atccacg----agcggttggcgtcgcggttggcg	Protospacer
    ***    .*********** **********

381. spacer 45.6|6864734|30|NC_008312|CRT matches to NZ_CP022581 (Gordonia rubripertincta strain CWB2 plasmid pGCWB2, complete sequence) position: , mismatch: 6, identity: 0.8

acggcgtggcggttggcgtggcggttggcg	CRISPR spacer
cggtcctggcggttggcctggcgcttggcg	Protospacer
  * * *********** ***** ******

382. spacer 45.6|6864734|30|NC_008312|CRT matches to NZ_CP032348 (Azospirillum brasilense strain MTCC4039 plasmid p4, complete sequence) position: , mismatch: 6, identity: 0.8

acggcgtggcggttggcgtggcggttggcg	CRISPR spacer
tcggcatggcggttggcgttgcggtcgcgg	Protospacer
 ****.************* *****.*  *

383. spacer 45.6|6864734|30|NC_008312|CRT matches to NZ_CP013589 (Rhizobium phaseoli strain N161 plasmid pRphaN161d, complete sequence) position: , mismatch: 6, identity: 0.8

acggcgtggcggttggcgtggcggttggcg	CRISPR spacer
ccgacgaggcggttggcgtggcggaaggag	Protospacer
 **.** *****************  ** *

384. spacer 45.6|6864734|30|NC_008312|CRT matches to NZ_CP025432 (Paracoccus zhejiangensis strain J6 plasmid pPZ02, complete sequence) position: , mismatch: 6, identity: 0.8

acggcgtggcggttggcgtggcggttggcg	CRISPR spacer
acgccgtggcggttggtgtggcgctcgtcc	Protospacer
*** ************.****** *.* * 

385. spacer 45.6|6864734|30|NC_008312|CRT matches to NZ_CP032703 (Pantoea dispersa strain DSM 32899 plasmid unnamed1, complete sequence) position: , mismatch: 6, identity: 0.8

acggcgtggcggttggcgtggcggttggcg	CRISPR spacer
gcgacctggcggttggcgtggcggcggacg	Protospacer
.**.* ******************. *.**

386. spacer 47.1|7278276|30|NC_008312|CRISPRCasFinder matches to NC_024355 (Staphylococcus phage 6ec, complete genome) position: , mismatch: 6, identity: 0.8

tttatcaattctaaattctcattattattg	CRISPR spacer
tttatcaagtctaaattctaattccttttc	Protospacer
******** ********** *** .* ** 

387. spacer 3.4|613093|29|NC_008312|CRT matches to KT997873 (Uncultured Mediterranean phage uvDeep-CGR2-KM21-C368, complete genome) position: , mismatch: 7, identity: 0.759

taaaaccaggagcaccatcagctccagcc	CRISPR spacer
gaggaccaggaggaccagcagctccagtt	Protospacer
 *..******** **** *********..

388. spacer 3.4|613093|29|NC_008312|CRT matches to NZ_KX893538 (Pseudomonas fluorescens strain PC20 plasmid pG20, complete sequence) position: , mismatch: 7, identity: 0.759

taaaaccaggagcaccatcagctccagcc	CRISPR spacer
caaaaccaggatcgccatcagctcgacga	Protospacer
.********** *.********** *   

389. spacer 3.4|613093|29|NC_008312|CRT matches to NZ_CP016083 (Streptomyces sp. SAT1 plasmid unnamed3, complete sequence) position: , mismatch: 7, identity: 0.759

taaaaccaggagcaccatcagctccagcc	CRISPR spacer
gatctccaggagcacgatcagcgccagct	Protospacer
 *   ********** ****** *****.

390. spacer 3.4|613093|29|NC_008312|CRT matches to NZ_CP028885 (Borrelia turcica IST7 plasmid lp129, complete sequence) position: , mismatch: 7, identity: 0.759

taaaaccaggagcaccatcagctccagcc	CRISPR spacer
gagcaccaggagcaccaacagcaccagga	Protospacer
 *. ************* **** ****  

391. spacer 3.4|613093|29|NC_008312|CRT matches to NC_009128 (Corynebacterium sp. L2-79-05 plasmid pLEW279a, complete sequence) position: , mismatch: 7, identity: 0.759

taaaaccaggagcaccatcagctccagcc	CRISPR spacer
cgaaaccaggaacaccatctgctcctggt	Protospacer
..*********.******* ***** * .

392. spacer 3.4|613093|29|NC_008312|CRT matches to NZ_CP004352 (Corynebacterium casei LMG S-19264 plasmid pCASE2, complete sequence) position: , mismatch: 7, identity: 0.759

taaaaccaggagcaccatcagctccagcc	CRISPR spacer
cgaaaccaggaacaccatctgctcctggt	Protospacer
..*********.******* ***** * .

393. spacer 3.22|614119|29|NC_008312|CRT matches to NC_007501 (Lactobacillus phage Lc-Nu, complete genome) position: , mismatch: 7, identity: 0.759

caagaccaggaacaccatcagctccagcc	CRISPR spacer
ttgcaccaggaacaccatcagcaccatct	Protospacer
. . ****************** *** *.

394. spacer 3.22|614119|29|NC_008312|CRT matches to AY131267 (Bacteriophage Lc-Nu, complete genome) position: , mismatch: 7, identity: 0.759

caagaccaggaacaccatcagctccagcc	CRISPR spacer
ttgcaccaggaacaccatcagcaccatct	Protospacer
. . ****************** *** *.

395. spacer 3.22|614119|29|NC_008312|CRT matches to NZ_CP032678 (Pseudomonas sp. Leaf58 plasmid pBASL58, complete sequence) position: , mismatch: 7, identity: 0.759

caagaccaggaacaccatcagctccagcc	CRISPR spacer
gaagcccaggaacaccatcagcaggaaca	Protospacer
 *** *****************   *.* 

396. spacer 3.24|614218|29|NC_008312|CRT matches to NC_012654 (Clostridium botulinum Ba4 str. 657 plasmid pCLJ, complete sequence) position: , mismatch: 7, identity: 0.759

taagaccaggaacaccatcagctccagcc	CRISPR spacer
cattgccaggaagaccatcagctccacca	Protospacer
.*  .******* ************* * 

397. spacer 3.24|614218|29|NC_008312|CRT matches to NZ_CP034811 (Paracoccus sp. Arc7-R13 plasmid unnamed1, complete sequence) position: , mismatch: 7, identity: 0.759

taagaccaggaacaccatcagctccagcc	CRISPR spacer
cagttccaggaacacgatcagcgccagcg	Protospacer
.*.  ********** ****** ***** 

398. spacer 3.24|614218|29|NC_008312|CRT matches to NZ_CP006909 (Clostridium botulinum CDC_1436 plasmid pCBG, complete sequence) position: , mismatch: 7, identity: 0.759

taagaccaggaacaccatcagctccagcc	CRISPR spacer
cattgccaggaagaccatcagctccacca	Protospacer
.*  .******* ************* * 

399. spacer 3.24|614218|29|NC_008312|CRT matches to NZ_CP031095 (Clostridium botulinum strain CFSAN034200 plasmid p1_CDC51232, complete sequence) position: , mismatch: 7, identity: 0.759

taagaccaggaacaccatcagctccagcc	CRISPR spacer
cattgccaggaagaccatcagctccacca	Protospacer
.*  .******* ************* * 

400. spacer 3.24|614218|29|NC_008312|CRT matches to NZ_CP032678 (Pseudomonas sp. Leaf58 plasmid pBASL58, complete sequence) position: , mismatch: 7, identity: 0.759

taagaccaggaacaccatcagctccagcc	CRISPR spacer
gaagcccaggaacaccatcagcaggaaca	Protospacer
 *** *****************   *.* 

401. spacer 3.24|614218|29|NC_008312|CRT matches to NC_009128 (Corynebacterium sp. L2-79-05 plasmid pLEW279a, complete sequence) position: , mismatch: 7, identity: 0.759

taagaccaggaacaccatcagctccagcc	CRISPR spacer
cgaaaccaggaacaccatctgctcctggt	Protospacer
..*.*************** ***** * .

402. spacer 3.24|614218|29|NC_008312|CRT matches to NZ_CP004352 (Corynebacterium casei LMG S-19264 plasmid pCASE2, complete sequence) position: , mismatch: 7, identity: 0.759

taagaccaggaacaccatcagctccagcc	CRISPR spacer
cgaaaccaggaacaccatctgctcctggt	Protospacer
..*.*************** ***** * .

403. spacer 3.29|614479|29|NC_008312|CRT matches to NZ_CP022775 (Ralstonia solanacearum strain T12 plasmid unnamed, complete sequence) position: , mismatch: 7, identity: 0.759

taagaccaggaacaccatcagctccagct	CRISPR spacer
cacatccaggaacaccatcagccccaggc	Protospacer
.* . *****************.**** .

404. spacer 3.29|614479|29|NC_008312|CRT matches to NC_014310 (Ralstonia solanacearum PSI07 plasmid mpPSI07, complete sequence) position: , mismatch: 7, identity: 0.759

taagaccaggaacaccatcagctccagct	CRISPR spacer
cacatccaggaacaccatcagccccaggc	Protospacer
.* . *****************.**** .

405. spacer 3.29|614479|29|NC_008312|CRT matches to NZ_CP022762 (Ralstonia solanacearum strain T95 plasmid unnamed, complete sequence) position: , mismatch: 7, identity: 0.759

taagaccaggaacaccatcagctccagct	CRISPR spacer
cacatccaggaacaccatcagccccaggc	Protospacer
.* . *****************.**** .

406. spacer 3.29|614479|29|NC_008312|CRT matches to NZ_CP023017 (Ralstonia solanacearum strain SL3022 plasmid unnamed, complete sequence) position: , mismatch: 7, identity: 0.759

taagaccaggaacaccatcagctccagct	CRISPR spacer
cacatccaggaacaccatcagccccaggc	Protospacer
.* . *****************.**** .

407. spacer 3.29|614479|29|NC_008312|CRT matches to NZ_CP014703 (Ralstonia solanacearum strain KACC 10722 plasmid, complete sequence) position: , mismatch: 7, identity: 0.759

taagaccaggaacaccatcagctccagct	CRISPR spacer
cacatccaggaacaccatcagccccaggc	Protospacer
.* . *****************.**** .

408. spacer 3.29|614479|29|NC_008312|CRT matches to NZ_CP022760 (Ralstonia solanacearum strain T98 plasmid unnamed, complete sequence) position: , mismatch: 7, identity: 0.759

taagaccaggaacaccatcagctccagct	CRISPR spacer
cacatccaggaacaccatcagccccaggc	Protospacer
.* . *****************.**** .

409. spacer 3.29|614479|29|NC_008312|CRT matches to NZ_CP022789 (Ralstonia solanacearum strain SL3175 plasmid unnamed, complete sequence) position: , mismatch: 7, identity: 0.759

taagaccaggaacaccatcagctccagct	CRISPR spacer
cacatccaggaacaccatcagccccaggc	Protospacer
.* . *****************.**** .

410. spacer 3.29|614479|29|NC_008312|CRT matches to NZ_CP022771 (Ralstonia solanacearum strain T51 plasmid unnamed, complete sequence) position: , mismatch: 7, identity: 0.759

taagaccaggaacaccatcagctccagct	CRISPR spacer
cacatccaggaacaccatcagccccaggc	Protospacer
.* . *****************.**** .

411. spacer 3.29|614479|29|NC_008312|CRT matches to NZ_CP022777 (Ralstonia solanacearum strain T11 plasmid unnamed, complete sequence) position: , mismatch: 7, identity: 0.759

taagaccaggaacaccatcagctccagct	CRISPR spacer
cacatccaggaacaccatcagccccaggc	Protospacer
.* . *****************.**** .

412. spacer 3.29|614479|29|NC_008312|CRT matches to NZ_CP022799 (Ralstonia solanacearum strain SL2064 plasmid unnamed, complete sequence) position: , mismatch: 7, identity: 0.759

taagaccaggaacaccatcagctccagct	CRISPR spacer
cacatccaggaacaccatcagccccaggc	Protospacer
.* . *****************.**** .

413. spacer 3.29|614479|29|NC_008312|CRT matches to NZ_CP022764 (Ralstonia solanacearum strain T82 plasmid unnamed, complete sequence) position: , mismatch: 7, identity: 0.759

taagaccaggaacaccatcagctccagct	CRISPR spacer
cacatccaggaacaccatcagccccaggc	Protospacer
.* . *****************.**** .

414. spacer 3.29|614479|29|NC_008312|CRT matches to NZ_CP022797 (Ralstonia solanacearum strain SL2312 plasmid unnamed, complete sequence) position: , mismatch: 7, identity: 0.759

taagaccaggaacaccatcagctccagct	CRISPR spacer
cacatccaggaacaccatcagccccaggc	Protospacer
.* . *****************.**** .

415. spacer 3.29|614479|29|NC_008312|CRT matches to NZ_CP022758 (Ralstonia solanacearum strain T101 plasmid unnamed, complete sequence) position: , mismatch: 7, identity: 0.759

taagaccaggaacaccatcagctccagct	CRISPR spacer
cacatccaggaacaccatcagccccaggc	Protospacer
.* . *****************.**** .

416. spacer 3.29|614479|29|NC_008312|CRT matches to NZ_CP049158 (Caballeronia sp. SBC1 plasmid pSBC1_2, complete sequence) position: , mismatch: 7, identity: 0.759

taagaccaggaacaccatcagctccagct	CRISPR spacer
aaagagcaggaacaccatcagcgcgctgt	Protospacer
 **** **************** *    *

417. spacer 3.29|614479|29|NC_008312|CRT matches to NZ_CP049318 (Caballeronia sp. SBC2 plasmid pSBC2-2, complete sequence) position: , mismatch: 7, identity: 0.759

taagaccaggaacaccatcagctccagct	CRISPR spacer
aaagagcaggaacaccatcagcgcgctgt	Protospacer
 **** **************** *    *

418. spacer 3.29|614479|29|NC_008312|CRT matches to NC_012654 (Clostridium botulinum Ba4 str. 657 plasmid pCLJ, complete sequence) position: , mismatch: 7, identity: 0.759

taagaccaggaacaccatcagctccagct	CRISPR spacer
cattgccaggaagaccatcagctccacca	Protospacer
.*  .******* ************* * 

419. spacer 3.29|614479|29|NC_008312|CRT matches to NZ_CP034811 (Paracoccus sp. Arc7-R13 plasmid unnamed1, complete sequence) position: , mismatch: 7, identity: 0.759

taagaccaggaacaccatcagctccagct	CRISPR spacer
cagttccaggaacacgatcagcgccagcg	Protospacer
.*.  ********** ****** ***** 

420. spacer 3.29|614479|29|NC_008312|CRT matches to NZ_CP006909 (Clostridium botulinum CDC_1436 plasmid pCBG, complete sequence) position: , mismatch: 7, identity: 0.759

taagaccaggaacaccatcagctccagct	CRISPR spacer
cattgccaggaagaccatcagctccacca	Protospacer
.*  .******* ************* * 

421. spacer 3.29|614479|29|NC_008312|CRT matches to NZ_CP031095 (Clostridium botulinum strain CFSAN034200 plasmid p1_CDC51232, complete sequence) position: , mismatch: 7, identity: 0.759

taagaccaggaacaccatcagctccagct	CRISPR spacer
cattgccaggaagaccatcagctccacca	Protospacer
.*  .******* ************* * 

422. spacer 3.29|614479|29|NC_008312|CRT matches to NZ_CP032678 (Pseudomonas sp. Leaf58 plasmid pBASL58, complete sequence) position: , mismatch: 7, identity: 0.759

taagaccaggaacaccatcagctccagct	CRISPR spacer
gaagcccaggaacaccatcagcaggaaca	Protospacer
 *** *****************   *.* 

423. spacer 3.33|614713|29|NC_008312|CRT matches to NC_012654 (Clostridium botulinum Ba4 str. 657 plasmid pCLJ, complete sequence) position: , mismatch: 7, identity: 0.759

taagaccaggaacaccatcagctccagcc	CRISPR spacer
cattgccaggaagaccatcagctccacca	Protospacer
.*  .******* ************* * 

424. spacer 3.33|614713|29|NC_008312|CRT matches to NZ_CP034811 (Paracoccus sp. Arc7-R13 plasmid unnamed1, complete sequence) position: , mismatch: 7, identity: 0.759

taagaccaggaacaccatcagctccagcc	CRISPR spacer
cagttccaggaacacgatcagcgccagcg	Protospacer
.*.  ********** ****** ***** 

425. spacer 3.33|614713|29|NC_008312|CRT matches to NZ_CP006909 (Clostridium botulinum CDC_1436 plasmid pCBG, complete sequence) position: , mismatch: 7, identity: 0.759

taagaccaggaacaccatcagctccagcc	CRISPR spacer
cattgccaggaagaccatcagctccacca	Protospacer
.*  .******* ************* * 

426. spacer 3.33|614713|29|NC_008312|CRT matches to NZ_CP031095 (Clostridium botulinum strain CFSAN034200 plasmid p1_CDC51232, complete sequence) position: , mismatch: 7, identity: 0.759

taagaccaggaacaccatcagctccagcc	CRISPR spacer
cattgccaggaagaccatcagctccacca	Protospacer
.*  .******* ************* * 

427. spacer 3.33|614713|29|NC_008312|CRT matches to NZ_CP032678 (Pseudomonas sp. Leaf58 plasmid pBASL58, complete sequence) position: , mismatch: 7, identity: 0.759

taagaccaggaacaccatcagctccagcc	CRISPR spacer
gaagcccaggaacaccatcagcaggaaca	Protospacer
 *** *****************   *.* 

428. spacer 3.33|614713|29|NC_008312|CRT matches to NC_009128 (Corynebacterium sp. L2-79-05 plasmid pLEW279a, complete sequence) position: , mismatch: 7, identity: 0.759

taagaccaggaacaccatcagctccagcc	CRISPR spacer
cgaaaccaggaacaccatctgctcctggt	Protospacer
..*.*************** ***** * .

429. spacer 3.33|614713|29|NC_008312|CRT matches to NZ_CP004352 (Corynebacterium casei LMG S-19264 plasmid pCASE2, complete sequence) position: , mismatch: 7, identity: 0.759

taagaccaggaacaccatcagctccagcc	CRISPR spacer
cgaaaccaggaacaccatctgctcctggt	Protospacer
..*.*************** ***** * .

430. spacer 3.35|614830|29|NC_008312|CRT matches to NZ_CP049158 (Caballeronia sp. SBC1 plasmid pSBC1_2, complete sequence) position: , mismatch: 7, identity: 0.759

caagaccaggaacaccatcagctccagct	CRISPR spacer
aaagagcaggaacaccatcagcgcgctgt	Protospacer
 **** **************** *    *

431. spacer 3.35|614830|29|NC_008312|CRT matches to NZ_CP049318 (Caballeronia sp. SBC2 plasmid pSBC2-2, complete sequence) position: , mismatch: 7, identity: 0.759

caagaccaggaacaccatcagctccagct	CRISPR spacer
aaagagcaggaacaccatcagcgcgctgt	Protospacer
 **** **************** *    *

432. spacer 3.35|614830|29|NC_008312|CRT matches to NZ_CP032678 (Pseudomonas sp. Leaf58 plasmid pBASL58, complete sequence) position: , mismatch: 7, identity: 0.759

caagaccaggaacaccatcagctccagct	CRISPR spacer
gaagcccaggaacaccatcagcaggaaca	Protospacer
 *** *****************   *.* 

433. spacer 3.40|615091|29|NC_008312|CRT matches to NZ_CP022775 (Ralstonia solanacearum strain T12 plasmid unnamed, complete sequence) position: , mismatch: 7, identity: 0.759

taagaccaggaacaccatcagctccagct	CRISPR spacer
cacatccaggaacaccatcagccccaggc	Protospacer
.* . *****************.**** .

434. spacer 3.40|615091|29|NC_008312|CRT matches to NC_014310 (Ralstonia solanacearum PSI07 plasmid mpPSI07, complete sequence) position: , mismatch: 7, identity: 0.759

taagaccaggaacaccatcagctccagct	CRISPR spacer
cacatccaggaacaccatcagccccaggc	Protospacer
.* . *****************.**** .

435. spacer 3.40|615091|29|NC_008312|CRT matches to NZ_CP022762 (Ralstonia solanacearum strain T95 plasmid unnamed, complete sequence) position: , mismatch: 7, identity: 0.759

taagaccaggaacaccatcagctccagct	CRISPR spacer
cacatccaggaacaccatcagccccaggc	Protospacer
.* . *****************.**** .

436. spacer 3.40|615091|29|NC_008312|CRT matches to NZ_CP023017 (Ralstonia solanacearum strain SL3022 plasmid unnamed, complete sequence) position: , mismatch: 7, identity: 0.759

taagaccaggaacaccatcagctccagct	CRISPR spacer
cacatccaggaacaccatcagccccaggc	Protospacer
.* . *****************.**** .

437. spacer 3.40|615091|29|NC_008312|CRT matches to NZ_CP014703 (Ralstonia solanacearum strain KACC 10722 plasmid, complete sequence) position: , mismatch: 7, identity: 0.759

taagaccaggaacaccatcagctccagct	CRISPR spacer
cacatccaggaacaccatcagccccaggc	Protospacer
.* . *****************.**** .

438. spacer 3.40|615091|29|NC_008312|CRT matches to NZ_CP022760 (Ralstonia solanacearum strain T98 plasmid unnamed, complete sequence) position: , mismatch: 7, identity: 0.759

taagaccaggaacaccatcagctccagct	CRISPR spacer
cacatccaggaacaccatcagccccaggc	Protospacer
.* . *****************.**** .

439. spacer 3.40|615091|29|NC_008312|CRT matches to NZ_CP022789 (Ralstonia solanacearum strain SL3175 plasmid unnamed, complete sequence) position: , mismatch: 7, identity: 0.759

taagaccaggaacaccatcagctccagct	CRISPR spacer
cacatccaggaacaccatcagccccaggc	Protospacer
.* . *****************.**** .

440. spacer 3.40|615091|29|NC_008312|CRT matches to NZ_CP022771 (Ralstonia solanacearum strain T51 plasmid unnamed, complete sequence) position: , mismatch: 7, identity: 0.759

taagaccaggaacaccatcagctccagct	CRISPR spacer
cacatccaggaacaccatcagccccaggc	Protospacer
.* . *****************.**** .

441. spacer 3.40|615091|29|NC_008312|CRT matches to NZ_CP022777 (Ralstonia solanacearum strain T11 plasmid unnamed, complete sequence) position: , mismatch: 7, identity: 0.759

taagaccaggaacaccatcagctccagct	CRISPR spacer
cacatccaggaacaccatcagccccaggc	Protospacer
.* . *****************.**** .

442. spacer 3.40|615091|29|NC_008312|CRT matches to NZ_CP022799 (Ralstonia solanacearum strain SL2064 plasmid unnamed, complete sequence) position: , mismatch: 7, identity: 0.759

taagaccaggaacaccatcagctccagct	CRISPR spacer
cacatccaggaacaccatcagccccaggc	Protospacer
.* . *****************.**** .

443. spacer 3.40|615091|29|NC_008312|CRT matches to NZ_CP022764 (Ralstonia solanacearum strain T82 plasmid unnamed, complete sequence) position: , mismatch: 7, identity: 0.759

taagaccaggaacaccatcagctccagct	CRISPR spacer
cacatccaggaacaccatcagccccaggc	Protospacer
.* . *****************.**** .

444. spacer 3.40|615091|29|NC_008312|CRT matches to NZ_CP022797 (Ralstonia solanacearum strain SL2312 plasmid unnamed, complete sequence) position: , mismatch: 7, identity: 0.759

taagaccaggaacaccatcagctccagct	CRISPR spacer
cacatccaggaacaccatcagccccaggc	Protospacer
.* . *****************.**** .

445. spacer 3.40|615091|29|NC_008312|CRT matches to NZ_CP022758 (Ralstonia solanacearum strain T101 plasmid unnamed, complete sequence) position: , mismatch: 7, identity: 0.759

taagaccaggaacaccatcagctccagct	CRISPR spacer
cacatccaggaacaccatcagccccaggc	Protospacer
.* . *****************.**** .

446. spacer 3.40|615091|29|NC_008312|CRT matches to NZ_CP049158 (Caballeronia sp. SBC1 plasmid pSBC1_2, complete sequence) position: , mismatch: 7, identity: 0.759

taagaccaggaacaccatcagctccagct	CRISPR spacer
aaagagcaggaacaccatcagcgcgctgt	Protospacer
 **** **************** *    *

447. spacer 3.40|615091|29|NC_008312|CRT matches to NZ_CP049318 (Caballeronia sp. SBC2 plasmid pSBC2-2, complete sequence) position: , mismatch: 7, identity: 0.759

taagaccaggaacaccatcagctccagct	CRISPR spacer
aaagagcaggaacaccatcagcgcgctgt	Protospacer
 **** **************** *    *

448. spacer 3.40|615091|29|NC_008312|CRT matches to NC_012654 (Clostridium botulinum Ba4 str. 657 plasmid pCLJ, complete sequence) position: , mismatch: 7, identity: 0.759

taagaccaggaacaccatcagctccagct	CRISPR spacer
cattgccaggaagaccatcagctccacca	Protospacer
.*  .******* ************* * 

449. spacer 3.40|615091|29|NC_008312|CRT matches to NZ_CP034811 (Paracoccus sp. Arc7-R13 plasmid unnamed1, complete sequence) position: , mismatch: 7, identity: 0.759

taagaccaggaacaccatcagctccagct	CRISPR spacer
cagttccaggaacacgatcagcgccagcg	Protospacer
.*.  ********** ****** ***** 

450. spacer 3.40|615091|29|NC_008312|CRT matches to NZ_CP006909 (Clostridium botulinum CDC_1436 plasmid pCBG, complete sequence) position: , mismatch: 7, identity: 0.759

taagaccaggaacaccatcagctccagct	CRISPR spacer
cattgccaggaagaccatcagctccacca	Protospacer
.*  .******* ************* * 

451. spacer 3.40|615091|29|NC_008312|CRT matches to NZ_CP031095 (Clostridium botulinum strain CFSAN034200 plasmid p1_CDC51232, complete sequence) position: , mismatch: 7, identity: 0.759

taagaccaggaacaccatcagctccagct	CRISPR spacer
cattgccaggaagaccatcagctccacca	Protospacer
.*  .******* ************* * 

452. spacer 3.40|615091|29|NC_008312|CRT matches to NZ_CP032678 (Pseudomonas sp. Leaf58 plasmid pBASL58, complete sequence) position: , mismatch: 7, identity: 0.759

taagaccaggaacaccatcagctccagct	CRISPR spacer
gaagcccaggaacaccatcagcaggaaca	Protospacer
 *** *****************   *.* 

453. spacer 3.45|615433|29|NC_008312|CRT matches to NZ_CP049158 (Caballeronia sp. SBC1 plasmid pSBC1_2, complete sequence) position: , mismatch: 7, identity: 0.759

caagaccaggaacaccatcagctccagct	CRISPR spacer
aaagagcaggaacaccatcagcgcgctgt	Protospacer
 **** **************** *    *

454. spacer 3.45|615433|29|NC_008312|CRT matches to NZ_CP049318 (Caballeronia sp. SBC2 plasmid pSBC2-2, complete sequence) position: , mismatch: 7, identity: 0.759

caagaccaggaacaccatcagctccagct	CRISPR spacer
aaagagcaggaacaccatcagcgcgctgt	Protospacer
 **** **************** *    *

455. spacer 3.45|615433|29|NC_008312|CRT matches to NZ_CP032678 (Pseudomonas sp. Leaf58 plasmid pBASL58, complete sequence) position: , mismatch: 7, identity: 0.759

caagaccaggaacaccatcagctccagct	CRISPR spacer
gaagcccaggaacaccatcagcaggaaca	Protospacer
 *** *****************   *.* 

456. spacer 3.63|616822|38|NC_008312|CRT matches to NC_010181 (Bacillus mycoides KBAB4 plasmid pBWB402, complete sequence) position: , mismatch: 7, identity: 0.816

caggacctacaggacctacaggaccagcaaggccagga------	CRISPR spacer
caggacctacaggacctacaggacca------ccagtaggtacg	Protospacer
**************************      **** *      

457. spacer 3.63|616822|38|NC_008312|CRT matches to MN693968 (Marine virus AFVG_250M909, complete genome) position: , mismatch: 7, identity: 0.816

caggacctacaggacctacaggaccagcaaggccagga	CRISPR spacer
caggaccaacaggaccaacaggaccagcaggttctggt	Protospacer
******* ******** ************.* .* ** 

458. spacer 4.2|617254|29|NC_008312|CRT matches to NZ_CP016083 (Streptomyces sp. SAT1 plasmid unnamed3, complete sequence) position: , mismatch: 7, identity: 0.759

caagaccagcgggaccaggagctccagtt	CRISPR spacer
gcggaccagcaggaccaggagcgccagca	Protospacer
  .*******.*********** ****. 

459. spacer 4.2|617254|29|NC_008312|CRT matches to MH171096 (Streptomyces phage Eddasa, complete genome) position: , mismatch: 7, identity: 0.759

caagaccagcgggaccaggagctccagtt	CRISPR spacer
gcggaccagcggggccagtagctccagcc	Protospacer
  .**********.**** ********..

460. spacer 4.2|617254|29|NC_008312|CRT matches to MN096381 (Streptomyces phage Rusticus, complete genome) position: , mismatch: 7, identity: 0.759

caagaccagcgggaccaggagctccagtt	CRISPR spacer
gcggaccagcggggccagtagctccagcc	Protospacer
  .**********.**** ********..

461. spacer 4.2|617254|29|NC_008312|CRT matches to MF541404 (Streptomyces phage BryanRecycles, complete genome) position: , mismatch: 7, identity: 0.759

caagaccagcgggaccaggagctccagtt	CRISPR spacer
gcggaccagcggggccagtagctccagcc	Protospacer
  .**********.**** ********..

462. spacer 4.2|617254|29|NC_008312|CRT matches to NC_028976 (Streptomyces phage Izzy, complete genome) position: , mismatch: 7, identity: 0.759

caagaccagcgggaccaggagctccagtt	CRISPR spacer
gcggaccagcggggccagtagctccagcc	Protospacer
  .**********.**** ********..

463. spacer 4.2|617254|29|NC_008312|CRT matches to MF541408 (Streptomyces phage Jash, complete genome) position: , mismatch: 7, identity: 0.759

caagaccagcgggaccaggagctccagtt	CRISPR spacer
gcggaccagcggggccagtagctccagcc	Protospacer
  .**********.**** ********..

464. spacer 4.2|617254|29|NC_008312|CRT matches to MF541409 (Streptomyces phage Oliynyk, complete genome) position: , mismatch: 7, identity: 0.759

caagaccagcgggaccaggagctccagtt	CRISPR spacer
gcggaccagcggggccagtagctccagcc	Protospacer
  .**********.**** ********..

465. spacer 4.2|617254|29|NC_008312|CRT matches to NZ_CP029835 (Azospirillum ramasamyi strain M2T2B2 plasmid unnamed5, complete sequence) position: , mismatch: 7, identity: 0.759

caagaccagcgggaccaggagctccagtt	CRISPR spacer
cgagaccagcggaaccaggagctgtcggc	Protospacer
*.**********.********** . * .

466. spacer 4.3|617317|29|NC_008312|CRT matches to NC_007501 (Lactobacillus phage Lc-Nu, complete genome) position: , mismatch: 7, identity: 0.759

caagaccaggaacaccatcagctccagcc	CRISPR spacer
ttgcaccaggaacaccatcagcaccatct	Protospacer
. . ****************** *** *.

467. spacer 4.3|617317|29|NC_008312|CRT matches to AY131267 (Bacteriophage Lc-Nu, complete genome) position: , mismatch: 7, identity: 0.759

caagaccaggaacaccatcagctccagcc	CRISPR spacer
ttgcaccaggaacaccatcagcaccatct	Protospacer
. . ****************** *** *.

468. spacer 4.3|617317|29|NC_008312|CRT matches to NZ_CP032678 (Pseudomonas sp. Leaf58 plasmid pBASL58, complete sequence) position: , mismatch: 7, identity: 0.759

caagaccaggaacaccatcagctccagcc	CRISPR spacer
gaagcccaggaacaccatcagcaggaaca	Protospacer
 *** *****************   *.* 

469. spacer 4.5|617434|29|NC_008312|CRT matches to NC_007501 (Lactobacillus phage Lc-Nu, complete genome) position: , mismatch: 7, identity: 0.759

caagaccaggaacaccatcagctccagcc	CRISPR spacer
ttgcaccaggaacaccatcagcaccatct	Protospacer
. . ****************** *** *.

470. spacer 4.5|617434|29|NC_008312|CRT matches to AY131267 (Bacteriophage Lc-Nu, complete genome) position: , mismatch: 7, identity: 0.759

caagaccaggaacaccatcagctccagcc	CRISPR spacer
ttgcaccaggaacaccatcagcaccatct	Protospacer
. . ****************** *** *.

471. spacer 4.5|617434|29|NC_008312|CRT matches to NZ_CP032678 (Pseudomonas sp. Leaf58 plasmid pBASL58, complete sequence) position: , mismatch: 7, identity: 0.759

caagaccaggaacaccatcagctccagcc	CRISPR spacer
gaagcccaggaacaccatcagcaggaaca	Protospacer
 *** *****************   *.* 

472. spacer 6.1|904049|29|NC_008312|CRISPRCasFinder matches to MW147367 (Synechococcus phage S-H9-2, complete genome) position: , mismatch: 7, identity: 0.759

ataatggggaaattgtagatgataattcg	CRISPR spacer
aagatgaggaaattgtagatgatgatgat	Protospacer
* .***.****************.**   

473. spacer 7.1|1110187|30|NC_008312|CRISPRCasFinder matches to NZ_CP032095 (Vibrio alfacsensis strain CAIM 1831 plasmid pVa1, complete sequence) position: , mismatch: 7, identity: 0.767

taggagatgatttttctgggtttagttcaa	CRISPR spacer
aacaagatgatttttttgggtttaggacac	Protospacer
 * .***********.*********  ** 

474. spacer 7.1|1110187|30|NC_008312|CRISPRCasFinder matches to NZ_CP018030 (Alteromonas mediterranea strain RG65 plasmid MRG65-300, complete sequence) position: , mismatch: 7, identity: 0.767

taggagatgatttttctgggtttagttcaa---	CRISPR spacer
caggaattgatttttctgggttta---cgaatt	Protospacer
.****. *****************   *.*   

475. spacer 12.14|1607246|27|NC_008312|CRT matches to MH617645 (Inoviridae sp. isolate ctcb11, complete genome) position: , mismatch: 7, identity: 0.741

tcaattattggcttttttagttatcag	CRISPR spacer
ctggggattggctttgttagttatcag	Protospacer
....  ********* ***********

476. spacer 21.37|2628935|26|NC_008312|CRT matches to NZ_CP016746 (Lactococcus lactis subsp. cremoris strain JM1 plasmid pMPJM1, complete sequence) position: , mismatch: 7, identity: 0.731

tgaagtttgaagttttaagtctcaat	CRISPR spacer
attagtttgaagttttaagtcttcta	Protospacer
   *******************.   

477. spacer 21.63|2630374|26|NC_008312|CRT matches to NZ_CP016746 (Lactococcus lactis subsp. cremoris strain JM1 plasmid pMPJM1, complete sequence) position: , mismatch: 7, identity: 0.731

tgaagtttgaagttttaagtctcaat	CRISPR spacer
attagtttgaagttttaagtcttcta	Protospacer
   *******************.   

478. spacer 21.80|2631158|26|NC_008312|CRT matches to NZ_CP016746 (Lactococcus lactis subsp. cremoris strain JM1 plasmid pMPJM1, complete sequence) position: , mismatch: 7, identity: 0.731

tgaagtttgaagttttaagtctcaat	CRISPR spacer
attagtttgaagttttaagtcttcta	Protospacer
   *******************.   

479. spacer 45.6|6864734|30|NC_008312|CRT matches to NZ_CP007129 (Gemmatirosa kalamazoonesis strain KBS708 plasmid 1, complete sequence) position: , mismatch: 7, identity: 0.767

acggcgtggcggttggcgtggcggttggcg	CRISPR spacer
tcggcgtggcgctgggcgtggcggtcgcgt	Protospacer
 ********** * ***********.*   

480. spacer 45.6|6864734|30|NC_008312|CRT matches to CP031732 (Stenotrophomonas rhizophila strain GA1 plasmid unnamed3, complete sequence) position: , mismatch: 7, identity: 0.767

acggcgtggcggttggcgtggcggttggcg	CRISPR spacer
actttcatgcggttggcgcggcggttggcg	Protospacer
**  .   **********.***********

481. spacer 45.6|6864734|30|NC_008312|CRT matches to NZ_CP054616 (Azospirillum oryzae strain KACC 14407 plasmid unnamed2, complete sequence) position: , mismatch: 7, identity: 0.767

acggcgtggcggttggcgtggcggttggcg	CRISPR spacer
gccctgcggcggtgggcgtggcggtgggcg	Protospacer
.*  .*.****** *********** ****

482. spacer 45.6|6864734|30|NC_008312|CRT matches to NZ_CP030263 (Ensifer adhaerens strain Corn53 plasmid AA, complete sequence) position: , mismatch: 7, identity: 0.767

acggcgtggcggttggcgtggcggttggcg	CRISPR spacer
gcggcgcggcggttggcgtggcttgcggag	Protospacer
.*****.***************   .** *

483. spacer 47.1|7278276|30|NC_008312|CRISPRCasFinder matches to NZ_FO818639 (Xenorhabdus bovienii strain CS03 plasmid XBC_p, complete sequence) position: , mismatch: 7, identity: 0.767

tttatcaattctaaattctcattattattg	CRISPR spacer
atagtcaattctaaattttcatttttatca	Protospacer
 * .*************.***** ****..

484. spacer 47.1|7278276|30|NC_008312|CRISPRCasFinder matches to KF929199 (Staphylococcus phage vB_SepS_SEP9, complete genome) position: , mismatch: 7, identity: 0.767

tttatcaattctaaattctcattattattg	CRISPR spacer
tttatcaagtctaaattctaattcattctc	Protospacer
******** ********** ***  * .* 

485. spacer 3.4|613093|29|NC_008312|CRT matches to NZ_CP012183 (Pseudonocardia sp. EC080610-09 plasmid pBCI2-2, complete sequence) position: , mismatch: 8, identity: 0.724

taaaaccaggagcaccatcagctccagcc	CRISPR spacer
agccttcgggagcaccatcagctgcagcc	Protospacer
 .   .*.*************** *****

486. spacer 3.4|613093|29|NC_008312|CRT matches to KU594605 (Cyanophage S-RIM50 isolate RW_29_0704, complete genome) position: , mismatch: 8, identity: 0.724

taaaaccaggagcaccatcagctccagcc	CRISPR spacer
caaaaccagcagcaccatcagcaagattg	Protospacer
.******** ************   * . 

487. spacer 3.4|613093|29|NC_008312|CRT matches to NZ_CP028885 (Borrelia turcica IST7 plasmid lp129, complete sequence) position: , mismatch: 8, identity: 0.724

taaaaccaggagcaccatcagctccagcc	CRISPR spacer
ccgcaccaggagcaccaacagcaccagga	Protospacer
. . ************* **** ****  

488. spacer 3.4|613093|29|NC_008312|CRT matches to NZ_CP028885 (Borrelia turcica IST7 plasmid lp129, complete sequence) position: , mismatch: 8, identity: 0.724

taaaaccaggagcaccatcagctccagcc	CRISPR spacer
ccgcaccaggagcaccaacagcaccagga	Protospacer
. . ************* **** ****  

489. spacer 3.4|613093|29|NC_008312|CRT matches to NZ_CP028885 (Borrelia turcica IST7 plasmid lp129, complete sequence) position: , mismatch: 8, identity: 0.724

taaaaccaggagcaccatcagctccagcc	CRISPR spacer
ccgcaccaggagcaccaacagcaccagga	Protospacer
. . ************* **** ****  

490. spacer 3.4|613093|29|NC_008312|CRT matches to NZ_CP028885 (Borrelia turcica IST7 plasmid lp129, complete sequence) position: , mismatch: 8, identity: 0.724

taaaaccaggagcaccatcagctccagcc	CRISPR spacer
ccgcaccaggagcaccaacagcaccagga	Protospacer
. . ************* **** ****  

491. spacer 3.4|613093|29|NC_008312|CRT matches to NZ_CP028885 (Borrelia turcica IST7 plasmid lp129, complete sequence) position: , mismatch: 8, identity: 0.724

taaaaccaggagcaccatcagctccagcc	CRISPR spacer
ccgcaccaggagcaccaacagcaccagga	Protospacer
. . ************* **** ****  

492. spacer 3.22|614119|29|NC_008312|CRT matches to NZ_CP049158 (Caballeronia sp. SBC1 plasmid pSBC1_2, complete sequence) position: , mismatch: 8, identity: 0.724

caagaccaggaacaccatcagctccagcc	CRISPR spacer
aaagagcaggaacaccatcagcgcgctgt	Protospacer
 **** **************** *    .

493. spacer 3.22|614119|29|NC_008312|CRT matches to NZ_CP049318 (Caballeronia sp. SBC2 plasmid pSBC2-2, complete sequence) position: , mismatch: 8, identity: 0.724

caagaccaggaacaccatcagctccagcc	CRISPR spacer
aaagagcaggaacaccatcagcgcgctgt	Protospacer
 **** **************** *    .

494. spacer 3.24|614218|29|NC_008312|CRT matches to NZ_CP049158 (Caballeronia sp. SBC1 plasmid pSBC1_2, complete sequence) position: , mismatch: 8, identity: 0.724

taagaccaggaacaccatcagctccagcc	CRISPR spacer
aaagagcaggaacaccatcagcgcgctgt	Protospacer
 **** **************** *    .

495. spacer 3.24|614218|29|NC_008312|CRT matches to NZ_CP049318 (Caballeronia sp. SBC2 plasmid pSBC2-2, complete sequence) position: , mismatch: 8, identity: 0.724

taagaccaggaacaccatcagctccagcc	CRISPR spacer
aaagagcaggaacaccatcagcgcgctgt	Protospacer
 **** **************** *    .

496. spacer 3.33|614713|29|NC_008312|CRT matches to NZ_CP049158 (Caballeronia sp. SBC1 plasmid pSBC1_2, complete sequence) position: , mismatch: 8, identity: 0.724

taagaccaggaacaccatcagctccagcc	CRISPR spacer
aaagagcaggaacaccatcagcgcgctgt	Protospacer
 **** **************** *    .

497. spacer 3.33|614713|29|NC_008312|CRT matches to NZ_CP049318 (Caballeronia sp. SBC2 plasmid pSBC2-2, complete sequence) position: , mismatch: 8, identity: 0.724

taagaccaggaacaccatcagctccagcc	CRISPR spacer
aaagagcaggaacaccatcagcgcgctgt	Protospacer
 **** **************** *    .

498. spacer 4.3|617317|29|NC_008312|CRT matches to NZ_CP049158 (Caballeronia sp. SBC1 plasmid pSBC1_2, complete sequence) position: , mismatch: 8, identity: 0.724

caagaccaggaacaccatcagctccagcc	CRISPR spacer
aaagagcaggaacaccatcagcgcgctgt	Protospacer
 **** **************** *    .

499. spacer 4.3|617317|29|NC_008312|CRT matches to NZ_CP049318 (Caballeronia sp. SBC2 plasmid pSBC2-2, complete sequence) position: , mismatch: 8, identity: 0.724

caagaccaggaacaccatcagctccagcc	CRISPR spacer
aaagagcaggaacaccatcagcgcgctgt	Protospacer
 **** **************** *    .

500. spacer 4.5|617434|29|NC_008312|CRT matches to NZ_CP049158 (Caballeronia sp. SBC1 plasmid pSBC1_2, complete sequence) position: , mismatch: 8, identity: 0.724

caagaccaggaacaccatcagctccagcc	CRISPR spacer
aaagagcaggaacaccatcagcgcgctgt	Protospacer
 **** **************** *    .

501. spacer 4.5|617434|29|NC_008312|CRT matches to NZ_CP049318 (Caballeronia sp. SBC2 plasmid pSBC2-2, complete sequence) position: , mismatch: 8, identity: 0.724

caagaccaggaacaccatcagctccagcc	CRISPR spacer
aaagagcaggaacaccatcagcgcgctgt	Protospacer
 **** **************** *    .

502. spacer 12.4|1606574|49|NC_008312|CRT matches to AP017993 (Planktothrix agardhii NIES-204 plasmid plasmid2 DNA, complete sequence) position: , mismatch: 8, identity: 0.837

tcagttatcatttatcagttatcaattatcagttttttcagttatcagc-	CRISPR spacer
tcagttatcagttatcagttatcagttatcag-tttttagtttatcccct	Protospacer
********** *************.******* ***** . *****  * 

503. spacer 12.6|1606695|47|NC_008312|CRT matches to AP017993 (Planktothrix agardhii NIES-204 plasmid plasmid2 DNA, complete sequence) position: , mismatch: 8, identity: 0.83

agttatcatttatcagttatcatttatcagttttttcagttatcagc-	CRISPR spacer
agttatcagttatcagttatcagttatcag-tttttagtttatcccct	Protospacer
******** ************* ******* ***** . *****  * 

504. spacer 17.1|1941253|35|NC_008312|CRISPRCasFinder matches to NZ_CP038863 (Campylobacter jejuni strain SCJK2 plasmid unnamed1, complete sequence) position: , mismatch: 8, identity: 0.771

taatagttaaagcaagaaattataaagatttaatt	CRISPR spacer
aaacatataaagcaaaaaataataaagatttaaaa	Protospacer
 **.*  ********.**** ************  

505. spacer 23.1|2941370|38|NC_008312|CRT matches to NC_015511 (Haliscomenobacter hydrossis DSM 1100 plasmid pHALHY01, complete sequence) position: , mismatch: 8, identity: 0.789

-------tttaggttttaggttttaggttttaggttttaagtttt	CRISPR spacer
aacctgttttacgttttaggttttaggttttaggtttt-------	Protospacer
       **** **************************       

506. spacer 45.6|6864734|30|NC_008312|CRT matches to NZ_CP054616 (Azospirillum oryzae strain KACC 14407 plasmid unnamed2, complete sequence) position: , mismatch: 8, identity: 0.733

acggcgtggcggttggcgtggcggttggcg	CRISPR spacer
tgggcgtggcggtgggcgtggcggcgacgg	Protospacer
  *********** **********. .  *

507. spacer 45.6|6864734|30|NC_008312|CRT matches to NZ_CP039899 (Agrobacterium tumefaciens strain CFBP5877 plasmid pAtCFBP5877a, complete sequence) position: , mismatch: 8, identity: 0.733

acggcgtggcggttggcgtggcggttggcg	CRISPR spacer
taggcgtggcggtttgcgtggcgcgtcaag	Protospacer
  ************ ********  * . *

508. spacer 45.6|6864734|30|NC_008312|CRT matches to NC_013855 (Azospirillum sp. B510 plasmid pAB510a, complete sequence) position: , mismatch: 8, identity: 0.733

acggcgtggcggttggcgtggcggttggcg	CRISPR spacer
tgggcgaggcggttggcgcggcggtccagg	Protospacer
  **** ***********.******. . *

509. spacer 45.6|6864734|30|NC_008312|CRT matches to NC_013855 (Azospirillum sp. B510 plasmid pAB510a, complete sequence) position: , mismatch: 8, identity: 0.733

acggcgtggcggttggcgtggcggttggcg	CRISPR spacer
tgggcgaggcggttggcgcggcggtccagg	Protospacer
  **** ***********.******. . *

510. spacer 45.6|6864734|30|NC_008312|CRT matches to NZ_CP030074 (Streptomyces sp. ZFG47 plasmid unnamed1, complete sequence) position: , mismatch: 8, identity: 0.733

acggcgtggcggttggcgtggcggttggcg	CRISPR spacer
gcggcgtagcggttggcggggcgggacagg	Protospacer
.******.********** *****   . *

511. spacer 45.6|6864734|30|NC_008312|CRT matches to NZ_CP023408 (Streptomyces fungicidicus strain TXX3120 plasmid p1, complete sequence) position: , mismatch: 8, identity: 0.733

acggcgtggcggttggcgtggcggttggcg	CRISPR spacer
agccgggaccggttggcgtgacggttggcg	Protospacer
*    * . ***********.*********

512. spacer 45.6|6864734|30|NC_008312|CRT matches to NZ_CP039890 (Agrobacterium tumefaciens strain CFBP5499 plasmid pAtCFBP5499a, complete sequence) position: , mismatch: 8, identity: 0.733

acggcgtggcggttggcgtggcggttggcg	CRISPR spacer
taggcgtggcggtttgcgtggcgcgtcaag	Protospacer
  ************ ********  * . *

513. spacer 45.6|6864734|30|NC_008312|CRT matches to KJ538722 (Mycobacterium phage HH92, complete genome) position: , mismatch: 8, identity: 0.733

acggcgtggcggttggcgtggcggttggcg	CRISPR spacer
gaggcgtggcggttggcgtgtccgtcgttc	Protospacer
. ****************** * **.* . 

514. spacer 45.6|6864734|30|NC_008312|CRT matches to KT222940 (Mycobacterium phage Kinbote, complete genome) position: , mismatch: 8, identity: 0.733

acggcgtggcggttggcgtggcggttggcg	CRISPR spacer
gaggcgtggcggttggcgtgtccgtcgttc	Protospacer
. ****************** * **.* . 

515. spacer 45.6|6864734|30|NC_008312|CRT matches to MH727549 (Mycobacterium phage Gancho, complete genome) position: , mismatch: 8, identity: 0.733

acggcgtggcggttggcgtggcggttggcg	CRISPR spacer
gaggcgtggcggttggcgtgtccgtcgttc	Protospacer
. ****************** * **.* . 

516. spacer 45.6|6864734|30|NC_008312|CRT matches to MK919482 (Mycobacterium phage DeepSoil15, complete genome) position: , mismatch: 8, identity: 0.733

acggcgtggcggttggcgtggcggttggcg	CRISPR spacer
gaggcgtggcggttggcgtgtccgtcgttc	Protospacer
. ****************** * **.* . 

517. spacer 45.6|6864734|30|NC_008312|CRT matches to MT657330 (Mycobacterium phage Webster2, complete genome) position: , mismatch: 8, identity: 0.733

acggcgtggcggttggcgtggcggttggcg	CRISPR spacer
gaggcgtggcggttggcgtgtccgtcgttc	Protospacer
. ****************** * **.* . 

518. spacer 45.6|6864734|30|NC_008312|CRT matches to MF919517 (Mycobacterium phage LilHazelnut, complete genome) position: , mismatch: 8, identity: 0.733

acggcgtggcggttggcgtggcggttggcg	CRISPR spacer
gaggcgtggcggttggcgtgtccgtcgttc	Protospacer
. ****************** * **.* . 

519. spacer 45.6|6864734|30|NC_008312|CRT matches to EU203571 (Mycobacterium phage Giles, complete genome) position: , mismatch: 8, identity: 0.733

acggcgtggcggttggcgtggcggttggcg	CRISPR spacer
gaggcgtggcggttggcgtgtccgtcgttc	Protospacer
. ****************** * **.* . 

520. spacer 45.6|6864734|30|NC_008312|CRT matches to MK494095 (Mycobacterium phage Daegal, complete genome) position: , mismatch: 8, identity: 0.733

acggcgtggcggttggcgtggcggttggcg	CRISPR spacer
gaggcgtggcggttggcgtgtccgtcgttc	Protospacer
. ****************** * **.* . 

521. spacer 45.6|6864734|30|NC_008312|CRT matches to MT818421 (Mycobacterium phage Luke, complete genome) position: , mismatch: 8, identity: 0.733

acggcgtggcggttggcgtggcggttggcg	CRISPR spacer
gaggcgtggcggttggcgtgtccgtcgttc	Protospacer
. ****************** * **.* . 

522. spacer 45.6|6864734|30|NC_008312|CRT matches to MH697577 (Mycobacterium phage Amochick, complete genome) position: , mismatch: 8, identity: 0.733

acggcgtggcggttggcgtggcggttggcg	CRISPR spacer
gaggcgtggcggttggcgtgtccgtcgttc	Protospacer
. ****************** * **.* . 

523. spacer 45.6|6864734|30|NC_008312|CRT matches to MT684594 (Mycobacterium phage Hadrien, complete genome) position: , mismatch: 8, identity: 0.733

acggcgtggcggttggcgtggcggttggcg	CRISPR spacer
gaggcgtggcggttggcgtgtccgtcgttc	Protospacer
. ****************** * **.* . 

524. spacer 45.6|6864734|30|NC_008312|CRT matches to MT114159 (Mycobacterium phage Ein37, complete genome) position: , mismatch: 8, identity: 0.733

acggcgtggcggttggcgtggcggttggcg	CRISPR spacer
gaggcgtggcggttggcgtgtccgtcgttc	Protospacer
. ****************** * **.* . 

525. spacer 45.6|6864734|30|NC_008312|CRT matches to KT246485 (Mycobacterium phage OBUpride, complete genome) position: , mismatch: 8, identity: 0.733

acggcgtggcggttggcgtggcggttggcg	CRISPR spacer
gaggcgtggcggttggcgtgtccgtcgttc	Protospacer
. ****************** * **.* . 

526. spacer 45.6|6864734|30|NC_008312|CRT matches to KT454972 (Mycobacterium phage Evanesce, complete genome) position: , mismatch: 8, identity: 0.733

acggcgtggcggttggcgtggcggttggcg	CRISPR spacer
gaggcgtggcggttggcgtgtccgtcgttc	Protospacer
. ****************** * **.* . 

527. spacer 47.1|7278276|30|NC_008312|CRISPRCasFinder matches to NZ_CP029455 (Bacillus cereus strain FORC087 plasmid pFORC087.1, complete sequence) position: , mismatch: 8, identity: 0.733

tttatcaattctaaattctcattattattg	CRISPR spacer
atatggaggtctaaattctcataattattg	Protospacer
 *    *. ************* *******

528. spacer 3.4|613093|29|NC_008312|CRT matches to NZ_CP011515 (Mitsuaria sp. 7 plasmid, complete sequence) position: , mismatch: 9, identity: 0.69

taaaaccaggagcaccatcagctccagcc	CRISPR spacer
ctcgcccaggcgcaccatcagctccatgt	Protospacer
.  . ***** ***************  .

529. spacer 21.51|2629736|40|NC_008312|CRT matches to NZ_CP015730 (Bacillus cereus strain A1 plasmid pBCA1, complete sequence) position: , mismatch: 9, identity: 0.775

ttaggttttaggttttaggttttaagtttgaggtctcatt	CRISPR spacer
ttaggttttaggttttaggttttaggtttgttactagatc	Protospacer
************************.*****  ...  **.

530. spacer 21.51|2629736|40|NC_008312|CRT matches to NZ_CP015730 (Bacillus cereus strain A1 plasmid pBCA1, complete sequence) position: , mismatch: 9, identity: 0.775

-------ttaggttttaggttttaggttttaagtttgaggtctcatt	CRISPR spacer
tacggttttaggttttaggttttaggttttaggttttagg-------	Protospacer
       ************************.**** ***       

531. spacer 23.1|2941370|38|NC_008312|CRT matches to NZ_CP015730 (Bacillus cereus strain A1 plasmid pBCA1, complete sequence) position: , mismatch: 9, identity: 0.763

tttaggttttaggttttaggttttaggttttaagtttt-------	CRISPR spacer
-------tttaggttttaggttttaggttttaggtttgttactag	Protospacer
       *************************.****        

532. spacer 33.1|4206516|31|NC_008312|CRISPRCasFinder matches to NC_003905 (Proteus vulgaris plasmid Rts1 DNA, complete sequence) position: , mismatch: 9, identity: 0.71

aagttgagctaataaataatctgctgatttt	CRISPR spacer
tacgtgagctaataaatcatgtgctgaaacg	Protospacer
 *  ************* ** ******  . 

533. spacer 44.1|6722439|35|NC_008312|CRISPRCasFinder matches to NZ_CP047427 (Spiroplasma citri strain C189 plasmid pScpC189-1, complete sequence) position: , mismatch: 9, identity: 0.743

gtcagtaaaaaaaaaattaagaattaattaaaagg	CRISPR spacer
aaagataaagaaaaaataaagaattaattaaaaat	Protospacer
.  ..****.******* ***************. 

534. spacer 44.1|6722439|35|NC_008312|CRISPRCasFinder matches to NZ_CP047431 (Spiroplasma citri strain BLH-13 plasmid pSciBLH13-3, complete sequence) position: , mismatch: 9, identity: 0.743

gtcagtaaaaaaaaaattaagaattaattaaaagg	CRISPR spacer
aagataaagaaaaaaataaagaattaattaaaaat	Protospacer
.  *  **.******** ***************. 

535. spacer 44.1|6722439|35|NC_008312|CRISPRCasFinder matches to NZ_CP046369 (Spiroplasma citri strain BR12 plasmid pScpBR12-1, complete sequence) position: , mismatch: 9, identity: 0.743

gtcagtaaaaaaaaaattaagaattaattaaaagg	CRISPR spacer
aagataaagaaaaaaataaagaattaattaaaaat	Protospacer
.  *  **.******** ***************. 

536. spacer 44.1|6722439|35|NC_008312|CRISPRCasFinder matches to NZ_CP042474 (Spiroplasma citri strain CC-2 plasmid pScpCC2-2, complete sequence) position: , mismatch: 9, identity: 0.743

gtcagtaaaaaaaaaattaagaattaattaaaagg	CRISPR spacer
aagataaagaaaaaaataaagaattaattaaaaat	Protospacer
.  *  **.******** ***************. 

537. spacer 44.1|6722439|35|NC_008312|CRISPRCasFinder matches to MT074137 (Bacteroides phage DAC16, complete genome) position: , mismatch: 9, identity: 0.743

gtcagtaaaaaaaaaattaagaattaattaaaagg	CRISPR spacer
aaagggaaaagaaaatttaagaattaattaaaatc	Protospacer
.  .* ****.**** *****************  

538. spacer 44.1|6722439|35|NC_008312|CRISPRCasFinder matches to MT074142 (Bacteroides phage DAC23, complete genome) position: , mismatch: 9, identity: 0.743

gtcagtaaaaaaaaaattaagaattaattaaaagg	CRISPR spacer
aaagggaaaagaaaatttaagaattaattaaaatc	Protospacer
.  .* ****.**** *****************  

539. spacer 44.1|6722439|35|NC_008312|CRISPRCasFinder matches to MT074141 (Bacteroides phage DAC22, complete genome) position: , mismatch: 9, identity: 0.743

gtcagtaaaaaaaaaattaagaattaattaaaagg	CRISPR spacer
aaagggaaaagaaaatttaagaattaattaaaaaa	Protospacer
.  .* ****.**** *****************..

540. spacer 44.1|6722439|35|NC_008312|CRISPRCasFinder matches to MT074141 (Bacteroides phage DAC22, complete genome) position: , mismatch: 9, identity: 0.743

gtcagtaaaaaaaaaattaagaattaattaaaagg	CRISPR spacer
aaagggaaaagaaaatttaagaattaattaaaaaa	Protospacer
.  .* ****.**** *****************..

541. spacer 44.1|6722439|35|NC_008312|CRISPRCasFinder matches to MT074146 (Bacteroides phage SJC03, complete genome) position: , mismatch: 9, identity: 0.743

gtcagtaaaaaaaaaattaagaattaattaaaagg	CRISPR spacer
aaagggaaaagaaaatttaagaattaattaaaaaa	Protospacer
.  .* ****.**** *****************..

542. spacer 44.1|6722439|35|NC_008312|CRISPRCasFinder matches to MT074139 (Bacteroides phage DAC19, complete genome) position: , mismatch: 9, identity: 0.743

gtcagtaaaaaaaaaattaagaattaattaaaagg	CRISPR spacer
aaagggaaaagaaaatttaagaattaattaaaaaa	Protospacer
.  .* ****.**** *****************..

543. spacer 44.1|6722439|35|NC_008312|CRISPRCasFinder matches to MT074140 (Bacteroides phage DAC20, complete genome) position: , mismatch: 9, identity: 0.743

gtcagtaaaaaaaaaattaagaattaattaaaagg	CRISPR spacer
aaagggaaaagaaaatttaagaattaattaaaaaa	Protospacer
.  .* ****.**** *****************..

544. spacer 44.1|6722439|35|NC_008312|CRISPRCasFinder matches to NZ_CP046372 (Spiroplasma citri strain LB 319 plasmid pScpLB319-1, complete sequence) position: , mismatch: 9, identity: 0.743

gtcagtaaaaaaaaaattaagaattaattaaaagg	CRISPR spacer
aagataaagaaaaaaataaagaattaattaaaaat	Protospacer
.  *  **.******** ***************. 

545. spacer 44.1|6722439|35|NC_008312|CRISPRCasFinder matches to NZ_CP047439 (Spiroplasma citri strain BLH-MB plasmid pSciBLHMB-2, complete sequence) position: , mismatch: 9, identity: 0.743

gtcagtaaaaaaaaaattaagaattaattaaaagg	CRISPR spacer
aagataaagaaaaaaataaagaattaattaaaaat	Protospacer
.  *  **.******** ***************. 

546. spacer 44.1|6722439|35|NC_008312|CRISPRCasFinder matches to NZ_CP047440 (Spiroplasma citri strain BLH-MB plasmid pSciBLHMB-3, complete sequence) position: , mismatch: 9, identity: 0.743

gtcagtaaaaaaaaaattaagaattaattaaaagg	CRISPR spacer
aagataaagaaaaaaataaagaattaattaaaaat	Protospacer
.  *  **.******** ***************. 

547. spacer 44.1|6722439|35|NC_008312|CRISPRCasFinder matches to NZ_CP053310 (Spiroplasma citri strain C5 plasmid pScpC5-6, complete sequence) position: , mismatch: 9, identity: 0.743

gtcagtaaaaaaaaaattaagaattaattaaaagg	CRISPR spacer
aagataaagaaaaaaataaagaattaattaaaaat	Protospacer
.  *  **.******** ***************. 

548. spacer 44.1|6722439|35|NC_008312|CRISPRCasFinder matches to NZ_LR214952 (Mycoplasma neurolyticum strain NCTC10166 plasmid 2) position: , mismatch: 9, identity: 0.743

gtcagtaaaaaaaaaattaagaattaattaaaagg	CRISPR spacer
ctgaattgaaaaaaaattaataattaaataaaaaa	Protospacer
 * *.* .************ ****** *****..

549. spacer 47.1|7278276|30|NC_008312|CRISPRCasFinder matches to NZ_LR134418 (Legionella adelaidensis strain NCTC12735 genome assembly, plasmid: 9) position: , mismatch: 9, identity: 0.7

tttatcaattctaaattctcattattattg	CRISPR spacer
cgcaaactttctaatttctcattattattt	Protospacer
. .*    ****** ************** 

550. spacer 23.1|2941370|38|NC_008312|CRT matches to NZ_CP015730 (Bacillus cereus strain A1 plasmid pBCA1, complete sequence) position: , mismatch: 10, identity: 0.737

-------tttaggttttaggttttaggttttaggttttaagtttt	CRISPR spacer
attcctagtacggttttaggttttaggttttaggtttt-------	Protospacer
        *  ***************************       

551. spacer 23.1|2941370|38|NC_008312|CRT matches to NC_015511 (Haliscomenobacter hydrossis DSM 1100 plasmid pHALHY01, complete sequence) position: , mismatch: 10, identity: 0.737

tttaggttttaggttttaggttttaggttttaagtttt-------	CRISPR spacer
-------tttaggttttaggttttaagttttaggtttagatgggg	Protospacer
       ******************.******.****        

552. spacer 23.3|2941508|33|NC_008312|CRT matches to NC_008270 (Rhodococcus jostii RHA1 plasmid pRHL2, complete sequence) position: , mismatch: 10, identity: 0.697

gttaattttctgaggttttaggtggtaggtttt	CRISPR spacer
cagaccagtctgacgtttttggtggtaggtttg	Protospacer
   * .  ***** ***** ************ 

553. spacer 23.4|2941561|38|NC_008312|CRT matches to NZ_CP015730 (Bacillus cereus strain A1 plasmid pBCA1, complete sequence) position: , mismatch: 10, identity: 0.737

-------tttaggtggcaggttttaggttttaggttttaagtttg	CRISPR spacer
gtacggttttaggttttaggttttaggttttaggtttt-------	Protospacer
       *******  .*********************       

554. spacer 23.6|2941688|38|NC_008312|CRT matches to NZ_CP015730 (Bacillus cereus strain A1 plasmid pBCA1, complete sequence) position: , mismatch: 10, identity: 0.737

tttaggttgcaggttttaggttttaggttttaagtttg-------	CRISPR spacer
-------tttaggttttaggttttaggttttaggtttgttactag	Protospacer
       * .**********************.*****       

555. spacer 3.62|616750|47|NC_008312|CRT matches to NZ_CP024776 (Bacillus thuringiensis LM1212 plasmid pLM8, complete sequence) position: , mismatch: 11, identity: 0.766

caggacctacaggacctataggacctacaggaccagcaagaccagga	CRISPR spacer
caggacctacgggacctacaggacctacaggacctagcggtataggg	Protospacer
**********.*******.*************** .  .*  .***.

556. spacer 44.1|6722439|35|NC_008312|CRISPRCasFinder matches to NC_010927 (Rickettsia monacensis strain IrR/Munich plasmid pRM, complete sequence) position: , mismatch: 11, identity: 0.686

gtcagtaaaaaaaaaattaagaattaattaaaagg	CRISPR spacer
attgtgaaataaaaaatttagaattaattaatgtt	Protospacer
.*..  *** ******** ************ .  

557. spacer 21.51|2629736|40|NC_008312|CRT matches to NC_015511 (Haliscomenobacter hydrossis DSM 1100 plasmid pHALHY01, complete sequence) position: , mismatch: 12, identity: 0.7

ttaggttttaggttttaggttttaagtttgaggtctcatt-------	CRISPR spacer
-------ttaggttttaggttttaagttttaggtttagatggggata	Protospacer
       ********************** ****.* . *       

558. spacer 21.4|2627320|47|NC_008312|CRT matches to NZ_CP015730 (Bacillus cereus strain A1 plasmid pBCA1, complete sequence) position: , mismatch: 14, identity: 0.702

-------tttgaggtgttaggtgttaggtgttaggttttaggttttaggtttga	CRISPR spacer
cattcctagtacggttttaggttttaggttttaggttttaggtttta-------	Protospacer
         *. *** ****** ****** *****************       

Prophage detection

Region	Region Position	Protein_number	Hit_taxonomy	Key_proteins	Att_site
DBSCAN-SWA_1	11373 : 91002	50	Ostreococcus_tauri_virus(33.33%)	transposase	NA
DBSCAN-SWA_2	1384182 : 1469674	57	Synechococcus_phage(30.0%)	tRNA,protease,bacteriocin,transposase	NA
DBSCAN-SWA_3	1661571 : 1764252	59	Vibrio_phage(16.67%)	tRNA,protease,tail,transposase	NA
DBSCAN-SWA_4	1843886 : 1944867	54	Synechococcus_phage(28.57%)	protease,holin,transposase	NA
DBSCAN-SWA_5	1962193 : 2023112	35	Phaeocystis_globosa_virus(20.0%)	tRNA,transposase	NA
DBSCAN-SWA_6	4685402 : 4740814	38	Prochlorococcus_phage(25.0%)	protease,integrase,transposase	attL 4723631:4723690|attR 4745955:4746117
DBSCAN-SWA_7	4838317 : 4949144	60	Wolbachia_phage(30.0%)	protease,transposase	NA
DBSCAN-SWA_8	5515787 : 5611019	50	Moumouvirus(16.67%)	tRNA,transposase	NA
DBSCAN-SWA_9	5699407 : 5783757	49	uncultured_Mediterranean_phage(16.67%)	protease,transposase	NA
DBSCAN-SWA_10	6564357 : 6616950	54	Sulfolobus_virus(25.0%)	tRNA,transposase	NA

Sequences of DBSCAN-SWA_1

Nucleotide sequences of DBSCAN-SWA_1

>NC_008312|11373:91002|DBSCAN-SWA
GTCAGAAATCTAAGGAATCGAAAACTCGATTTTTCAAGAATTTTTTCACCTCTTTCCACAGTCTTTCAATGGGATTAACTTCGGGACAATAAGGAGGTTGAAATAATAAAATGATGTGATCAGGGATAGATAAATCATTCCCTAGATGCCCTCGCCCGTTATCTAATTGAATAATATGAATCTCTTCAGGATATGTTTGAGAAAAAAGCTCTAAAAATCTTTCAAAGCAAGGAGTATCTAGATGACTAAATTCATAAAAAAAGGAATCTCCTGTTTTTGGTTCTACTAAACCATAAAGCCATAGATATTTAAATAGCCATTGATATAAACCAATGGGCTTAACACCGCAAGCAGTAATGACTTTACCTGTTATAGTTTTTAATCCAATTCTAGTCTCGTCTTGACACCAATAGCGAATTGGCAGTTGATTTTCCGAATATTTATTAATTAACTTAATTTTCTCTTCTAGTTGAGATGAGAGTTTTTTTTAAAGTTTTCTTGAGCTTCTTTATTTTGTTTTATGTGATTTGGACGTGGAACTTTTAATTTACTTTTTAATTTATATCTGACTAATTGATGAACTGTTCGATAAGACAGCTCGATGTCAAAACAAGTCGTTAACCACTGTTGAATTTCACCATAGCTTTGGAAACCTTCCGGGTTTTGCAATTCTGCTTCTAATTTCTCGATTACATTTGGTGGAATTGAACTTGGCCTCCCTCCTAGATTTTTCTTTGGTTCTAGTAAAAGATTCAGTCCACCTGTACGATATTTCCCTAACCATTTTTGTACTGTGACTCGATTGCGTCCTAACATTATCGCAATTTCTTTTACTGTTTCTACTGTTTGAGTTTTCAACCAGTAAATAGTTTGAAGTCTTTCCTTTTCTTGAGCTGTACTCGCACTTTTTAAAAGTTTTTTGAGAGTTTCTACCGATTCATTTATCTCAATTTTTACTACTCCTGACATGGGGACATTTTCTATAATAGGTTACTTCTAAAAGTGTAGCTTAAGTTTATGAAATTAGTATTACTTTTTAGGAATAGGTTTTGATAAATCGGGTTAATGGGTAAGAGATTCAGAGTTTATTTCTATTTTTGGTAATTGTGATAACCCATAGGAAGATTGCTATATATATAGCAGTTTTTTAATCTATAAGGTACAATCTTATATCTCCCTCTAACTCATGTTAAAGCGGATAAGCTTTTCAGGTAATTCCTGAAAAATGTAGGCTTTATAAACCTCTTTCTTAAACAAAAAACTTGGCACAATTAAAAATTAATGTGTTTGTAATTAAAGGGATATTTATTAGCATTAAATTTTTTTAAAAATGTGTTTTTTAAAACCCTTTTTTTATGTCATTTTCCCTTTATAAAAACTCCATATACTTATCCATTCTTGAGAAAATATTTGAAGTTTTTTATGATAATAGATAGATTACAAATCTATATTTATGGGTATCATAAATGTGCAGATAACTATGGGAATTGGGATAAAAAATTAAATTAATTGGTTAAAAAATATGGCAAATGAATTAAGAGAAGGTGACAAAACTCCTGTTGACTATAGTAGTTTATTAAAACAGATTTTAAATGAATTACCAACAATGAATCCATTTAAAGTATCTAGTAATAAGAAAATTTTAGAAATAAATATTGATGATATAGCTGCTTGTATTGCTAAGACAAAAGTTGAAAATCCTATCAGTAATACTATATCTGTTCGTTCTGCCACAGTAAATTTTGCTAGTGAAAAAAGTTTTTCGGAAAAAATTCAAGAAATAAAAGGTTGTCTAGAAACTCATTTCAGTTCGGCTTTACAAGGAGAAAATTTAGTTTATTTTATTGAAGGTTTAACTACTAATTTAGAATCTTTTCAGGGACAAGCAAATAAGTTAGGTTTGTCTTATCCTTTTAATGAAGAATATAAAGGACTACAAACAAAAGAATTAATTTTAGATTCTAATAAAAATGGCAGTGATTCTATACTGAGGTTTGCTAAACTAACAATTACAGTAGAGAATACTAAAAAGTTTATATCTCAGCTAGAAACAGGAATTAAAAATCATATATCTGATTCTTTTGAAACTGATAATCAAGGAGAAATGGAAGGTGCTTTAGATATTTTAAATAGTCAGATAAACGAAGAATCATCAAATTTTAATTTATTGCAAAAACTGGTGGATCAAGAAACTCTAGGAAAACTGAAAAGAGAAGCAATTATTACCTATTTAAAATATATTGAGCAAAATGTTGACAGCAAATATAAAAATACTAAAGGTTTTATTTATCTACAGGATTTAATTCGGCGACTAAAATTAATAGAAGAATATCTAGACGAGCAAACTGATGATTTTGAAGTTTACTACGCTGGAGTAACTGTTAATTATAAAGATGTTTTTGCTCGTGGGGAAGCCTTTGATGCTCTCCCAATTATTCCTATTATTGAAGGCAATTTAGGGGAAAGTAGAGATAAAGAAGTAGGAAAAGTTCAGTTTACATTAGGTTTAAAACTTAAGTTGAATGGCAAGGTACAAAAAGATAGAGGTAAAACTTCTTTTGAGTATAATTTAGATATTATTAACCCGGAGAATTCTGAGCATAAAGCAAAACTAGCTGATCCGGATATTCAAAGTCGAGAAAGTTTTGCTAAGAAGGTATTAATTAGAGTGTTTTTATACTATTTTATATTTGCCTGTGATCCTCCTTCATTAATGAATGATGAACTTCTTTATAACCCTAGGCTTAAGTTCGAGCAGGTTTTAATTGATTTAAAAAGTAGTAAGCATGATGATGAAAAAAGGAAAATTTTCCGGGGCATAGTCAAAGGTTTTAGTGAATATCGTGTTCAAGAAAAAGTTAATAGTCTATGTCAATTTTTAATCAATTTTATCAACAAAAAGAAAAGGTTGCCAGTATATCATGAAAATCAGGTAATTAGTATTAGTAGAGAAATCCTAAATAAGGACTTAGATAGTATTTCTATAGGAGATTTTTTTCAGGAAGATTGGAGAGAAGGAAAGAAAATTCTTAAATATATTTTCATTGATAAGCCTGGGGTAAATTCTTATACTCTATGTCAAATACCAGTTATTATCAAAATAGAAGATATTCGATATTTTCAAGGAGATAGTAATCCAAAAGAATTCAAGTTTGAATATGACATTCAAGGAATGAAAACATTACCTATGTTTTGGATACCTAATACTAACCCTTGTTTAGATAATTATAAAGCTTATTTTGAGAAAGAATACAAACACATATTATTTTATTATGATAATAAACGCTTAAATCAAGATAGACAAAACCAAGAACATTTCAATTCTACACAAATATTTCTTTATCGTTTTACTTGGATATTATTGTCTTATCTTTGTTTATATATTCTTCTTGAGGAATGTAGTGAAGAGACGAAGGAATTATTATTTATCCCTATGGTTAGACTACATGAGGGAACGCCGGCAAATCCATTTCATACTGAAAAATTTTTAGCTGATCTTTCCAAATTATTATGTCATATATTCAACCAAAAATATCTATGTAATTCTCAAGGGTTCCGGGTAGAAATGAATAAAAGACCTAAAAATTTTCAGATTAGAAATGGCTTAAACTCTCTATATTCTGTATTATCTAAAAAGTTTACCTTAACAGATACTTCTAAATTTTTAAACCTGGAAAAATTAGCAATTATTATTGTATCAAGTCGAGAAAGTGATGCCAAAAAAAATAATAAAAATTCTAATGATAGGATCATAACTTTAATAGGAGAAGTTATAGGTATTGAAAAACTCGAAGATGGCAGTGTAAAAATTCAACCATTAATAACTTTTGATAATAATTATTATCTCAGAAAGATGTACGAAAAGCCACCGATTTTAAATGAAACTGTAAAAGACCTTTATGTTCAGGGATACCAAAATTTTTTATATGTTGCTCAAGCAACTTACACTAGTACTTTACATATTACTCAACAAGAACAAGATGAGAAACTATATTTTATGTCGCCTACTATTATTAAAGATATGAAGCAAGGTCAGAAAAATATTAAAATATATCCAGTATTTTATGATAAATATTATGTACATCCTTTTAAAAGTTTGGATAGCCATTCTTTTTATATCCAAGACACTAAACAGTTAATGAATATTTCTGAAGATAGTAGTCAAGAAGCGGTTGTATTTTTCAATCTGTTTAATGGTATTTTAGTGGGAAATAACGAACGATTTTATAATGGGGTGATTTCATATTCGACTTTGTTAGGAAAATTTTATCCTGGAGTTATGGATGATGCTGATATTCGAGAAGCTTTAGTTTTAGACTCTCAGCTTAAAAATGACATTTTACAATATCTGACGTTTTTCCACTTTTCACGATTTGAAAGACAAACCAAAGTTAGTTTAAAGTTAGACCCATACGAAAATATTATTGGTGATAAATCAGTAGGTGCTTTATCTATATTTCCTCACCTTACAGAAAACATAAATTTTAATGCATTAGCTTTTTTAATAGAGGTTAATAAAGTAGTAGATGTATATTTTTAAAGGAAGAAAAAAATGAAGATGACATATCAGTTAGGATTTTGATTGGTGGTAGGTTTTAATATTGCCATTCTTGTAAATATTAAATTCCACGAATTTACAAATAATTTTGGTAATTGATATCTTCAATATTTGCATTTTTTAAAATTATATAATTATTATGCAATGGGTGAATAAAAATATTCAATTATTACTATTTCAATTTTCAATATTCTCGAAATCCACGGTAAATACAGCCTGTTAATACTCAAGCTTTGTATAGTTATTTCAGTATATTTACTCGACAAACATAAAGACTGAATTACATACTAATAAAACTATTGAATGGGCTATATTTTATTTGTAATTAGTTTCTAGCATAGCAACTTGTGTTGGTATGTTTGTATAAGATAAAGTGTCACTCGTGCTGCACGAATGAAAGTAATGTTAATAGTAGCAAAAATTTCTAGTATATTTAAAGATAATAGTAATATGTAAATATCTGAGCCCTATTGCTATAGTATGAAATTTTGCCTATAAAGTCAGTAAAAAAATCAAGCAACATAAAAATATTATCAATTATGAGTAGTTAGTAATTCGTCTGTATTAATCACACATAAAAGATACATTTTAATTTAATAAATTAGTATTTTAAATCCGGGTGAATAAAATCTTTTATTCGATACCTTGTTTATATTCCCTCATATTACATAAAAGATAAATTGTCATAAATTAGTATTTTTGATAGAGTTTACTAAAATTCTAAATATAGATTTTTAAAGAGAAGCAACAATTTACATAAAAGATAAATTGTCATAAATTGGTATTTTTGATAGAGTTTACTAAAATTCTAGATATAGATTTTTAAAGGGAAGCAAAAATTAATATTACAGACAAGTTAGAATTTTGATTTTAGGTAGGGTTTAATGTTCTTATTATTGTAGATATTCAATCCCAAAAGTTTACAAATAATTTTGTTGATGTATATCTTTAATATTTGCAGTTATTAAAATTACATAATATAATGAAATGGATAAATAAAAATTGATTAAATTATTAATATTAAAAGTTAAAATATTATCGAAATATTGAGTAAATACAGCCTATTATTACTCAATTTTTGTACAGTTATTTGAGTATATTTGCTCGACAAATAGAAAATATCAATTTTAATAAATTAGCATTTTTGATAAAGGTTACTAAAACCGCAGATTTAGATTTTTAAAAAGAAACAATAATGAAGATTACAGACAACTTAGGATTTTTATTTGAAGTAGGATTTAATATTGGTATTCTTGCGGATATTCAACATCAGAAGTATCAAAATAATTTTGGGGATTTGTATGTTCGGGATTTGCAGCAATTAAAATTGCCGAGGATGGTTAAACGAATGAGTCAAAATCATAGCATTATTGACCCTGAAAGTATTAAAAATCTGGAAATATGGAGTCGATATTTTATATTAAAAGGATTTCTAGGGGGATTAATTTTTTTCCGCGAGTATATTAAGTCAACTAAATGGAATTTAGAACCCAAAAAACTAAAAATTTTGTATTACCAATGTTGCTTTCATGGAGATAATAGTTTAGGTACTAATAATAAAGATAAATTATTAGGAATTGAGGAGTTATTATCTCAATTTTTATCTGTTGATGACTTGAATACTAATTTAAATAGATACGTTAATCAATATTTGGGAAAGAAAGGAGAATTTTTACAAGCAGATACATTAATTTTGTTGGGTGATGACCAACAGTTGAGAATTATCTGTGTAGATATGTCTATATTTTCAGTCGCTTCCGAAAAAGATTTGGTACCACTGAATGATAATAAGTTAAACAATTTACGTAAAATTTTGATGACGGATATTAAACATATTCATTCTAAAAGTGTCTTTTCTAAATTGCGGATAGATACAGGTAATACTAAGGATTTTGATTTTGTGTTTTCCTCAGATTTTAAAAGCTTTTTTACTGCTTTTAAGCGGAAGGATAAGGAAACTACTAAGTTAATTCAAGCAGGTGCTTATGCTGAAAGTTTTTACAATTTTCTGCTAAAGGAAACACAAATAATTACAGATAAAAAATCTGTTCTGTTTAATATTGTGGGATATAGCGATCGCAACATTAGTACTTTATGTTTACGCCCAGAAAATCTCAATATTTTAACTACTTGTTCCGAAATATATAAGAAGGAAGATAAAAACAAAGAAACTAAAGTCGCTCGTCGCAAAGTATTAGATTTGATTAAGAACAGAGCTGTTTTTAGTTTTATTAATGGCAAAGCTCTTACTGAAAATTTAAAGACAAAAAAGTTAAACTTTTCAGGGGATGGTATTGCTCGGGTTATTCATGAAGAAAAGTTGAATGATTTTGTTAATTCTATAGATGTTATCTCTGATAAATTAGCAGCAAAATTGGGTTTAAAGTTAGGGTTAAACTTAAGAGATGCTCATGCTGAATTAATTGAAAAAGCCCTAATTAGTGATAATACTTTTGTCTTTTTGACAGGTAACCCAGGTATAGGTAAAACAACAGCTATTGCTAATTTTTTAAAGTCTCATTTAGAGGAAGGTTTTCTCTTTTTTTATATTAGCCCTCGGATTCAAGTTAATCTCGATCTAATCCATAAGTTTAAATCTGAAAATGCTCAAGATCAGGAGCTTTTTGACGACAGATTATTTTGTATCAACACCAATTCAATTATAATTCAAGAAAATGATAACTATTCCACGGTTAGATATTATTCTAATCAACGTCAAGATGATTTTACTTCTAAAAATGTCCGGTTTATTAATTACAATTCACAAGCTGAACCTAGAAAGCAACGTCAAAGAAATTTTCATAGAATTACCGTAGATAAAATTGAAAATAGAAAAAAAATAACTGCTGGAGTTCTTGATAGTGTCTGTAAGGGAATATATGCTATTATTAATGACAAAATATCTAATAATATTGTTGCTACGGTTTCAACTCAATCTTTAAAAATTACTCCGAATGGTAGAGATACTATTGAACATCTTAAGACAATATTCAAAAGTACTTATGACAGAAAAAGAGGTGTAAATCCTGATAAAATGTACGAAATTTCTCAGAGGATAAAGCACTTATTTATAATGATTGATGAAATTACTGGTGATGATAGTGGAGTTCATTTTTTAAAGGGAATTAATAAGTTTTTGGGGCAGTATCAATTAACTAATTCAGAATATGGTTTTAATACTAAAGTTATTGTAGCTGATGCTTCTATTGTGGAACAAGAAGTTATTCAACAGCACTTATCACAAGAGTCCCCAGAACCAGATAAAATTTATTTTAGAGCAGCGAAAAGTCAAGCAGAAGCACTTTCAGTACAGGATTTTCAATTTAAAAATAAACGAGCTGTAACTATTAATGCTAATTCTTACCCAGCTAGTAGTTTAAATATTACTTATAAAGTCTTCATTCAATCCATTAACTTTAATCAATATGACTGGAAATTTAAAGAAAAAAACCAGTTGACGAAAGAAGTCGATTTAGAAATTTTATCAGATATAAAATACTTCTTAGAAAATTATAGTTCTAGTCAGTTATTAGTCTATATTCAAAACAAAAAACGTTTAAAGAGTTTGATAAAAAATATTAAGGAGTCACATAAAAATTTTGATGAATATACAGACTATCTGGAAATACATGCTAGTTTATATGATGAAAAAAGAAAAAAAATAGATAAGTATAAGCAAGATGTAAAAATCGTGTTTATGACATCTTCAGCAAGTCGAGGTTTATCTTTCCCTAAAGCTAAAAAAATCTTAGTTGAAATACCTCGTTTCCAGATCGAAAAAAATCTTATGGAAGTAATTCAAGTAATTTATAGAGCTAGAGGTCAGTATCAAGAAAATGGAAAAAAAATAACTTTAGATGATCAAGAAAAAGAAATAATATTTTATTTTAGTGATTCCGCAATTTATTATCCTAAAGATAATGATACTTCCCTGGAAAATTACGATGAAGAGAGAACCCTTTCTTTGGAAGAAAGTACAATGAATTTATTAGATATGTTATTAATTCTCAAACTTTCAATAATGACTAGGATAGTCGGTGCTGGTAATTTGGGAAGTAAAAAATTTCTGATGGTTCCTATTGGTGGAAAATCTATTTCAACAGCAGGAAATAGCTTTTCAGAAAAGATGACTAACCTAATTCGAGAGTTAAAAAATGAACATAACCGACATCCAGAAAAACAAAGTCTTCAGTATGTGTATTCTAGTCTGACACAAATTCTTAAGGAGGCAGTATTTTCTTTGCCTAATTCTAATTCTGATTCTAAAAATATTACTTATCTTTCCCTAATAGGTTTTTTAAAGACTGAACTTCCAACATTATTTAACCGACTCGATAAATTCTTAAATTTTGGTAATATCGAAACTGGTCATTTGACTGGTAATTTATTGGTAGTACCTATTTATAACCAAGCATTAGAAGAGACTTATCAAATAGAATTAGAAAATCAAATTAGAAGGTTTGCTAATAATGAATTAGTTAATAAAATGTTGTCAATTATGAAAAGTAAAGATTATCCACCTAATATTAAATCTGCAATTGAAAGTCCTTTAGAGTTAATCAAAATTCTTAAGGGTGACAAGGGTAATATTAATACAACTCAATGGTTTGAACAAAATAGTAATAATTTAGACCAGTATTATGCTGTGCCTTTGTTTGTATTTATCAGTGGAGAATTAATGAGTAAATATTTTAAGCAGGAACTTGAAGAAGAAGAAGAAGAAACGGCATTTAGAACTCTCTTATCCAAATATATTCACTCCCTTTATCCCGCATATAATACTCTACCTATTGGTCGGAAATATAAGGAGTTTCCTTTTATTGTTTTTCGCAGCTATAGTTTAAAGGAAATACGAGAAAAAATTTATAGCGATCGCTATCTTTTAACTTCTAATGAGTTGAATGTTCTTAACTTAATTCTTTCCCGAGAGGAAAGATCATGATACTAAACAATTAACAAAATTAATACTATATTTACGCGACGCTTCAATTATTAATTAACCCTCGCTGAAAAAATCTTTTATTCAGTTAATAGAAAAGGGAACAGTCACTATTACAATGGATGTAGTTGTTAATTTTTCGACATTAAAATACCTAAAAAAAAGCTAAAAAATTAAGGATTAAAAACTCAGTAAAAATCCTAGAATTCAAAGCTAGCTGCTGAAATAAATTTAAAAGTATGACAAATGTTGCTAAAAACCACATAAATTATGTCTACTTTTAATTTTATATTATAGGAGTAGACTGACAAATAATCTTTCTGCTTTAAACATAAAGAAAAAAATCAAAACCTGCTCCTACAAAAAAATAACTATCCTAAACTTTTGCCACTTCAGCAAATCTAATTTTCAAATAATCATCCTCCATTTTTGCCCCCACAGGTTGCAATGATGCTAAAGCTTGAGGTAAAACTAAATTCCGACGATGATTACCAATTCTAATATTCAACTCATCTCCAGTTTTATTCAATTGAATTTTCTCTTTAGGAATTCCTGGCAAATATAATTCCAAATTATAATTACCCTTTTCTTGCACTACCTTAACAGTATTTTCCTTATAATAAACCTGACTGGGATCTTCATCTCCATAAAGAGTTTCTTTCAACCTCTTCAAAGCAGCTAAACCACACATTTCTTCAGAATAAAGAGGTACTTCCTTCACAGGTAAAGGTCTAAAATTATCGTGAATTTCTTGCCGATATTGCTGTTGATTTTCCTTCCACTTTTTAAAGAAAGGGTCACTTACAGAATCAGGAATAATTCGATTTGCTACTACTAAATCTGTCGAAACATTGTATAAACTTAAATAAGCATGAGCGCGTAAAGACTCCTTAATTACCATTTTTTCAGGATTAGTAATTAAACGCACAGAAGTCTTAGTATTATCAGTTAAAACCTTTTCTAAAGCCTCAATTTGCTCATAAAATTCATAAGGAGCATCCATAACTTCTTTATCTGGCAAAGAAAAACCAGTAATAGGTTTAAAAATAGGCTCAAAAAGAGGTCTCAATGCTACCGACATTCCCTGCAAAGGTTTATAAAACTTTCTCATATACCAACCCCCCACTTCTGGTAAACTCAAAAGTCGCAAAGCAGTACCAGTTGGAGCAGAATCAATAATTAAAACATCGTATTCCCCCTCGTCATAGTGACGCTTCATCCGCACCAGGCCAAAAATTTCATCCATTCCTGGCAAAATTGCTAACTCTTCAGCTTGTACACCATCCAAACCGCGTGCCTGCAAAACTTGAGTAATGTAACGTTTTACAGCTCCCCAGTTTCCCTCTAGTTCCATCAAAGCATCCAACTCAGCACCCCAAAGGTTTTCCTTCACTTTTCGAGGTTCATGGCTCATTTCCATATCAAAGCTATCTGCTAGGGAGTGAGCTGGGTCAGTGCTGAGAACCAGAGTTTTATGGCCTAACTCTGCACAACGTAATCCTGTTGAGGCGGCCACTGATGTTTTGCCAACACCACCTTTTCCCGTCATTAATATTACACGCATCAATTATTTAACCTTTTCTGAATGATGTTTACATATTTTAACTTTAGCGGGTTTTTTACTTTTTCAGTGTTGAGGAGATTTTACATACCAAAATTGTATTTTTTTGTCAATCAATATATCTACATTGTCGAAAATAAGCTGATAATTATTTACCGAAGAATAGATCTTAATTATATTAATTATTGTCAATATGTGAAGCCTCAAACCACCCAATACCAGAGCTGCTTAGTATTAATCATCGCGCCTTTACACAGGGAAGGATCTTAGTTGAAAAAGCTGTTTTAAAACGTCCAGTCGAGAGATATCCCAATAGTCAATATGACTGTTAATTAGTCCATCTGCATTCAGTTTTAATTCACTCCATCCTGGAATTGCCATTGGAGGTTTCCAGGGGACAGGGGCGGTCCAGCTAAGTGTCCAACGAGTTTTAATCACATTTCCTGACTGACTAATATCGTGCAAGTCAAGTTTAATATCATTAAACCAATTGTTCATAAAACCGATCATTTTTTGATAACGCTCTATGCCTCGAAATTTATTTAGTGGATCTTCAAAGTAAACATTTTCTGCGTAAATACTATAAGTTTGGTCAGCAGGAAATTTTTGATAATCTTGTTTAAGTCTTGAAATAATATCCATTTTGTTTCTTACCTTCTCTTTTTCTTCCTTGTTAAATTAAAAAATTATTGAGTATTTTCTTTAAGTAGTTATGCAAAATTAATTACACATACCTGCTTATGTTTAACAGCCTAAACGTTTAAAAATAATAGTCAAGAAATAATGGTAATTAATTTTCCCTAGGTACTTAGTAGGTAACCATTCAGGTGCCTTCAGTGTAATCACACCATTGATTACCAGAAGCGAAATTATCGAATATTGTTTTTCTTGACAAAAAGAATAAACTAGGGTAAGATTATAGAGTTATTCAATCATAGATCCGATTAAATTTCTGAATGTCGTAAACCATTGTCAAAAACTGAACTGGTTAAAACGCTATTGACTTAACAGAAAGTTATAGATAAACTTTAGGAACTCTCTTGAGAAATTACAACAGACTTAAAACTTAGATAGTAAGATATTCTCCAAGCCTCCATAAACTGATATACTGAAAAAGTCCGAGGATGCTTTAGCAAAAGAGGAACCTCCAAATGATAAGAAAAAGAGACTACCAGGAGGAAAAAATTTTTTTTTACCTTTGGCGATCGCTCTTATTATTTGTTTTCTCAAACTCATTGTTTATTTCAAACCTTACTTTTTAGGAAAATCTTCATCATATAAAGCTTTATCTCAATTTTGAGCAGACTTAACTTGCTCAATAGTCAGAGCTTGAATGCTCCTAAAGTCAGCCTGCAAGAGGTCCATATTTTAGCAATTAACGTTTGGCATATAAGCTTTACTGAAATTAGCTTCATTGAGTTTAGCTCTCGAAAAATTTGTTCCATCTAAATTTGCATTTGATAAATCTGCTTTTGAAATATCAGCAACTTGAAATTGAGCTTTTGGTGCATGAGCAGAGTTGAATTTATCCTCTTCAAGATTAGGCTCTGATAAATTACTTCCATTGTCTCTTAGGATTTTTCGTAAGTTATAGTTGATTATAACTAAGCTAATATTTTCACTATTAAGGTAAGTTATTAATTCCCAGTTATCTTCTCCTAAATTAGTATAATTTTTCACCCGAAGAGTATATGCTTTTAAGTTTTCTAGATTAATTAATTGAATAAAAATTTGCTCTAACTTTTTTCGCTTCTCATCATTTAACTGTTCATATACCTCCTTTGCATGGTTAGCAATTGATTTTTTTACACCACCAATTTCTTCATAAATATTGTGAGTTAATTTAGCATTAGTTTGTTTGTTCCATAGTTGTGTTAAAGTCAATTCTAACAAAGGCAAATTTTAAGCTTTATTATTAAGATTCCCATAAATTATCAAACTATTCAGCAATACTTGATTACTAGACGTAAGAAGCATTTATCCTTATCTATACAAACTTATACTACTATCATAATTATTTGAGCCCTTCTACCTCTTCAATCAGTTTTTCTATTACTTATTATTGTTGCTAAACCAGTTTCCCTAGAGCTTCTTTAAACATTCATTCTAGGTTTTTCGGTATTTTAAGATATCTGGTGGCTTAAATTTCATTTTTCTACTTTAATACAGACCTTTACTTTTTTGTTAGCCTATTATTCTTTAATCATGCTTTCTCAAAAAATAGCTCTAACTCCTATTACTCCTGCCTCCTACCTTCATTTCGCCTATTTCTTTTACTCTCAAGCCGTAGCTCCGATGCAGGTTGACGTCTTAAAGACTAATGCACCCACCCCTAATAGAGGTGGGCAAGGCAGGGCGATCTGTCTATTTAAAATCTGGGAATACCCGAGGGCGACTTACAAAAAAAATTTATGGGTCTTTATTTGTGCTTTAGTGAAAAGAAGCTGCTCCGAAATCTGAAAGCTTCCCAAGTTAAATTCTCAACTTCGGAGAGTTTCGAGGAACCTCTTCTTTTCTACAGCATTTTATGAGATAAGGCACGTATAACAAACCCTACACATTAATTAATTGAAAGTCGCCCGATGGGCGGGCGAGGTAATAAAGCAAATTTTTCGGTAAATTTGGGTAAGAAAAAAGAGCATTTAGTCCTTTAATAATGATGACCAAACTTACAGAAACTTTTATGAGAAAGTCCCAATTACTTTTTTTAGTAATCAAACTTTCTACCCTATTAAAAGAGGCTTTTTCTCTTTTTTTGTACTTTTCTACTGGTCTTTGACATTTCCAGGAGTTGAAACATTCTGGTGTCTCTTGCAAATCAACCGAAAACAGGATTTATCCACATTTTGTTTAAGTCTGTCAACATATTTCTACTGATAATTTAAACAGCTGTCCAGACTTTAACTGGTAATTATTTAACTATAACTATTTAATTAATAGTAATGAGCAATAATACTCAATGTCATGATCGTTACCTTCTTGGGCTCTGAATAAATCAACTAATATATTTTTAGCTCATCCATTCCAGAATAGCTTCTTCTTTTTTATTGGTATGACGCTCTGGAGTTTCACGAGTGAACTGCATATGAATAGAGCGGTTTTGTTCACCATCAACTGCTACTGCCATAATTGGGTAATCAATCAAACCATCAGGGAAAGCCATCTGGAAGCGGAATGTACCATCAGGGTTCAGTTTAATGGGTCGTCCACCGATGGTAACAGTAGCATCAGGTTCAGTTGCACCGTGGATAATAAGTTCAGCATCAGCAACTAACCAGAACTTGCGGGGGCGAATTGGTGGGATGGAGCCAGCAATACCTGACATATTCATACCCATACCCGAAGCAGTTAAACCTACTCCTGACATATTCATACCCATACCCGAAGCAGTTAAACCTACTCCTGACATATTCATACCCATACCCGAAGCAGTTAAACCTACTCCTGACATATTCATACCCATACCCGAAGCAGTTAAACCTACTCCTGACATATTCATACCCATACCCGAAGCAGTTAAACCTACTCCTGACATATTCATACCCATACCCGAAGCAGTTAAACCTACTCCTGACATATTCATACCCATACCCGAAGCAGTTAAACCTACTCCTGACATATTCATACCCATACCCGAAGCAGTTAAACCTACTCCTGACATATTCATACCCATACCCGAAGCAGTTAAACCTACTCCTGACATATTCATACCCATACCCGAAGCAGTTAAACCTACTCCTGACATATTCATACCCATACCCGAAGCAGTTAAACCTACTCCTGACATATTCATACCTACACCCGAAGCAGTTAAACCTACTCCTGACATATTCATACCCATACCCGAAGCAGTTAAACCTACTCCTGACATATTCATACCCATACCCGAAGCAGTTAAACCTACTCCTGAAGCATTTAAGCCTACACCCGAAGCAGTTAAACCTACTCCTGAAGCATTTAAGCCTACACCCGAAGCAGTTAAACCTACTCCTGAAGCATTTAAGCCTACACCCGAAGCAGTTAAACCTACTCCTGAAGCATTTAAGCCTACACCCGAAGCAGTTAAACCTACTCCTGAAGCATTTAAGCCTACACCCGAAGCAGTTAAACCTACTCCTGAAGCATTTAAGCCTACACCCGAAGCAGTTAAACCTACTCCTGAAGCATTTAAGCCTACACCCGAAGCAGTTAAACCTACACCCGAAGCAGTTAAACCTACTCCTGAAGCAGTTAAACCTACTCCTGAAGCATTTAAGCCTACTCCTGACATAGTTTGACCAACCCCTGACATCATTTGATTGCCACAAGAAACATTGCTACCAGATGCCCACATCCCTAGACCTGATACCATAGCATAAGAGCTTAGTGTTTCTTCAATCATCTGGCCTGAACCTGGAACCATTTGAACAGAACCAAACATAGAACCAGAAACCCGTTTATCCTCAGCCTCAGCTATGCCAAACATTCCTTGATAAATATCATCATGATTATCATGAAAAGTAATTTGACGACTAGCAGGAAAAAGTTCCATAAAGGTTTTTCCACGCAAATCTTCATCCCAACTAACTGTGATGAATTGCTCGTCAATCCAATCTGAAGGATAAACTGGGGGAATATTTACTTCCTCAGAACGAGACAAAACTAACCAACGACCATCAGCACACCGATAACCTATTTCCACAGTATAGTTGCGATCGCTTACCGGAATAGGTATGTACCATTCACGAGCTAATTCATCACAAGGATATTCCTGAATGCTATGAGGACTTTGAGAGTCTAAGTTAATATCCGTGACATCATATGTACGGAGAGCTAACTGTTGCCCTCCTTGACTACGTAGCTCTTCTTTAAGTTCATTCGAAATATCCCAGTAAGCGTATGCCCACTCTGGGTCCCTTGGCATTAGTACTATTTTACTTTTAGCATACCCGTTAGGCAAGTCAGTTAAACCTTCATCAACTGATGAAAAAAAATCATCAATATTATTTTCTTCGCCTGATTCAAACTTTTTTGCTTCCGCTCTTTCTTGTACTTCTAATTTTGAAAGTGGAGCGGATGAAAGATTATTCATACCTTGAGCCTCTATAACTGCTGCCAAAAGTTGTGCTTTACGCATTCTGCTGTAACGAGAGATACCTAGCTCACTAGCAACTTTGCGTAGTTGCCTTAAAGTCATCTCTTCTAAGGGTGGACGTTCTTGAACCATTGTGTATATTCTTATATTTTTTCTTTCACTGTTTTATATTCTATTTCCCAAAACCTAGCAAGTTATTACAAATAATTCCTTATTTCTTTTGATAACTAATTAAGTGTCACTTAAACCAATTAATGATTTAGGTGAATCCATTAGAACTCTTAGGAGTTTCTAGACATTTGGGATCGCCTTATAAGTTTATATCTTGCAGAAAATCTTAGGTTTGGTGAAGGGTCGTCACTCAAAAATTATGAGCATATATTTGAATTCATAGGCAATTTTAGACTTATAATATTATTTTCCCTTAACTTAACTTAATTTTATGATAAATTCAAGCAAATTGGTTAATAAAATTGCTTTATAGTTTTATTCAAAGTTACTAATACCAACTCTGATAAATGTTTGCTATGAACGTCTAGTAGTCTATCAAGATTGATTTTATGCCCCTTGTTTATTTTTACCTTTTGTTTTCTCAATTTAGTTTTAACTCATAAGCATGAAAATTGACAAACCATTTAGGAGCTTCTTGACCTAACTCAGAAGTTAAGATAGAAATATTCTCAATCTCTATCTATAGTTAATAATTTATCTTGTTAGTCAAAGAGGTATCTTATATAAATTATTGTTATAGCCAAAACTAATTCCAAAATATTCTTCTTTTACCCTTGGTATAATAGATATATCCCCAACAATCTTAACCATTTACTATAACTATACTTTAGCACTTTTTATGTCGTGTACAAAAATGCTATTGTCTTCTTTATCATTATTTTCTACTAGTATTAATAATTCTATTCTTGAGCAGAAAAAAAACTTCTGGTTCAAATTACCTTTTTATAAATTTTATTCTTTCAATCTTTTTCTCAATCTTTTCCCTTGCTTTTGAGATTAATTTTACTTTATTTATTATCTACTTTTTCCACTTATTTAACTACACTTTGTTTCCCTTAAAGATGCATAATTTTAGATTCAAGAGTAAATTAAAATTTCTATTTTATCAGATTATGAACTAAACAAAGCAGTTAGAGAAAACTTAAAAAAAATTTATACATTACTTGAGAATCAAGTTACATTCATTATAAATCTTATACAAAGCAACTACAAATAAATTCATGCTTTAGTGTCAAGACGAAACTACAATTAAATTAAAATTATCACTGGTAAAATTATGACTGCTTGTGGAGTTAAAACCAATCAATAGTCGGAAGATGGTAATCAAACATATGATTACTATTCAGAAATGGTATTAGCACTACTTATCTTAAGTCTTAGTATCTTTTGTCCCTTATTCTGAGAAAATTAAATACATAACACCATATAAAAAATACTATGCCAGAGAATTTGAGAAGTCAATTAGTCACCAAAGGAGTACAACGCGCTCCCAACCGAGCTATGCTGAGAGCTGTGGGTTTTGAAGATTCAGACTTTACCAAACCAATTATTGGGGTTGCCAATGCCCATAGCACTATTACTCCCTGCAACATGGGTATTAATGATTTGGCCATGAGAGCTGTAAGTGGAGTGAAAGAAGCTGGAGGAATGCCGCAGATATTTGGAACTATTACTATTAGCGATGGAATTTCTATGGGTACTGAGGGGATGAAATATTCTCTGGTTTCTAGAGACGTTATTGCTGATTCCATCGAAACAGTTTGTAATGGCCAAACAATGGATGGAGTTCTAGCTATTGGTGGATGCGATAAAAATATGCCAGGAGCAATGATAGCGATCGCTAGGATGAATATTCCTGCTATCTTCGTATACGGTGGTACTATTAAACCAGGCAACTACAACGGTAAAGACCTAACAGTTGTAAGTGCTTTTGAAGCAGTGGGAGAATATAGTGCTGGAAAAATTGACGAAACAGAATTAACAGAAGTTGAACGTAGAGCTTGCCCTGGTGCTGGTTCCTGTGGAGGAATGTTTACTGCCAATACTATGTCTTCAGCTTTTGAAGCAATGGGTATGAGTCTCATGTATTCATCAACAATGGCTGCAGAAGATGCAGAAAAAGCAGATAGCACAGAAAAATCAGCTCATGTTTTAGTAGAAGCTATTCGCAAACAAATTTTACCTAGTCAAATTATTACCCGTAAAGCTATCGAAAATGCAATTTCAGTAATTATGGCTGTAGGGGGTTCCACTAATGCAGTACTACACCTATTAGCAATTGCTTATGCTGCAAATGTGAAGTTATCTTTAGATGATTTTGAAATAATTAGGGCCAGAGTACCTGTATTATGTGATTTGAAACCTAGTGGTAAATACGTTACAACAAATTTGCATCAAGCGGGTGGAATTCCTTTAGTAATGAAAATGCTTTTAGAACATGATTTACTCCACCCAGATGCTTTAACCATAACAGGTAAGACTATTGGAGAGCAATTAACAAATATACCTTCTGAACCACCTTCTAATCAAGACGTGATTCGCCCTTGGAATAATCCTATGTATGCTCAAGGACACTTGGCTATTTTAAAAGGAAATTTGGCGACAGAGGGAGCAGTTGCTAAAATTACAGGAGTGAAGAACCCAGAAATAACAGGACTAGCAAGAGTATTTGATTCGGAAGAAGCTTGTTTAGAAGCAATATTAGCAGGGAAAATTCAAGCAGGGAATATTATTGTAGTTCGCTATGAAGGTCCAAAAGGTGGACCAGGTATGCGAGAAATGTTAGCACCAACTTCGGCTATTATTGGTGCTGGTTTGGGGGATAAAGTGGGATTAATTACTGATGGTAGGTTTTCTGGTGGTACTTATGGTATGGTGGTTGGTCATGTAGCTCCAGAAGCTGCAGTAGGTGGCACGATCGCTCTAGTTAAGGAAGGAGATATGATTACTATTGATGCTCATAAGCGTTTACTACAGTTAAATATTTCTGATGAGGAATTAGAAAAGCGTCGTCAAGTATGGAAACCACGAAAACCCCAATATACTAGAGGTGTATTAGCTAAATATGCTAAGTTAGTTTCTTCTAGCAGTGTTGGAGCAGTAACTGACGCTGGATTAGGTTGAAATTTAGTTAATAATTATTAACTTTTGGTTTGATCGTAATACCATATAGTTAAATACCATAGAATCCATTTTGTATCTTTATTTAAGCGAAAATTAGCTTTTGAAGTGGCTAGTATATTTAATAATTTTGGATGCTTATAATATCCAATTTTGAACTATTAATGTCAAAAATAACTAAACTAAAAAACTTGAAAAGCTTATAACTAGACAAGGAGATATCAAATGGATTCTATACAGTTGAGATAGTTAGATAATGAGATAATTAACTAAAAAAAAAAGGAAAAACTATGGTTACTTAATTAATTTTCTTCTTAAGAAACCGTATATAATCAGTGAATCTAGGCAACCCTTCTATAATCAGGTTCTAATTTTAGGGTTGGTTACCTCTAAACAATATAAATACCATTTTTACTAGTCAATGTTTAGAGTATTACTGAAAATGCAAATGTGGAACTTAATAGTACAAAATTTATAAGTTAACCCCGAAAATTAATTTTGCAATTAACAATACACTAATTATTTTATCTATATAATTTTAAGTAGGAAATAGAGTTCTTACAAATCATATTTTTATTGCACAATTTTTGATTGATATAGATTGAAAAAAGATACTAACAAAATACGACTTTCAGTGGAAATTTTGTCTCAGCTTAAGAAGTTCCTGTACTAAAAAATTGCTTTGTTGTAAAGTTTAATAGCGAGAATAATAAGACTTGGGAAAATAACAAATTTGATAATTAATCAACCAGCACTAAGTAAATCGGGTAAAATATATAATTGGATATATAGCAATCCTAAGTAGGTTGCGGCAAAATTTCATACTGAAAAAGTTTTGGGAAATTGAATATTTGACCATCCGCAAAAAACTTAAATAGCCACTTAACTACTTTAAAAGAACTGCAAAGATGATAAAAAGTAATACTGAAATTTTTGGTTTGTAACCAAATATCTTCAACAGGATTTTGCTCCGGAGCATTGGGAGCAAATCTTGTACAATTTATCAACAATTCTTCTTCTGATAAGTATTGATTAATTGTCATTAAATATTCTCGAAATTCTTGAGAGTTATGGTAAGTTGCCCCATCCCAAAATATTGCCAATTTGTTGCCCGGTCTTTGCTTCTGCAAATATTTAATAAATTCAATAGTATTTTTAGTATTTCCACTCTCATATTCTTGCACAAGAAATTCCTTGGTTTTATAGTCTAAAGCTCCATAATAAGTCTGTCTTTCTTTTTCATTTTTAATTGCAATTTCTATTCTTTCATCTGTTTTTCCCCAAGCATAACCTAATATGTCTCCCCATAGAAGATGACATTCATCAATCATAAACACTGTAAGCTTTCCAGTTTCTATTTCTGGTTGCCATTTAGCTAAAAATTCCTCTATTTCTTTTCTTTTAACTTCTACTAATTCATCATTTTTAGCAGGATTCTTTTTTTGAGTTTTTTTCCAACTTATGCCCGCTTCTTTAAACAAGTTATAGTAACTTTGATTAGACTCAAAAACCACATCATATTGCTCCTGTAAGTAGTTTTTTAAATCTGATAACCTAAGATAATCTTGTGCTCTCAACCACTCAATTGTTTTCTCTTTTTCGACCGTTTTTAAGTAACCTTGTCTCCCTTGATACTGAAGCCTTAAACTTTCTACACCATGAAATAATGCTTGGTTTTTCCATTCACTAATAAAACTGTGAGAAACATTTAATAATTCTTTGACTTCATGGTAGGATTTTCCTGACAAGGTCATTTTTACGGCCAAGGCCCTTTTAATTTCTTTAGACTCTTTTGTTTGATTAATAAAATTATTTAGTTTATCTATAATATTCATTTTTTGTCTTTTTCTTAGATCTGTTATTCTTACTATTATATCTGTTGCGACCAATATGGGATTGCTATAACATAATTTCGGCGAGTGTCTGAGGAAATATATTGGTAAAAACGGTTATCGAAGAAACTAAACAAAACTAGATTTGTGTCCAATCTATTTGTCAGTTTGTTAAAGTATATGATAAGCTGGACATACTTAAATTTATGAAATCTCTGTGACTTAAATATGTAGCTTAATAGCTAGAATATAGATATTTTAAGAAAACATTAATTTTAGATAAAAAAAATCCTGTATAAGATTTTAACCTTATTTTTAGCCTATTTTTTCTTCAATTCCTGCTAGTAGGTAAGATTGACATCAAGAAATGGAGTATGGAGAGTTATAAGACAATAAGGTTTATATAAGACCAAAACTCATAAAGAATGAAGGAGAGTTATAAGACAATAAGGTTTATATAAGACCAAAACTCATAAAGAATGAAATTTTAAGATGAGTTTTTTAGATTACAGAACTGTCGAAAAAAATCCTTAACTGAAATGTATTTAGTTATGGAACGAAGGTAGATTTTTCTCTATTATCTATTGCTTATAGTTATGAATTATTCTCAGCCTCTTCGTAATTCTCAAACTATTTTGGGTAATATTACCCAGATGATAAAAACTATTCATGCTAGTGTCAACTTTTCTAGACTAGCAATTAGACCTAATGCTAGAGTACCTGAACTATGGATAGAGGAAGGAAAAGCTACTCCAACTAAAAAATATCCTCTTTTGGGTGATCGTTATTTGCTCGGACGCTCCTCCCAAGCTTGTGACATTGTTATTCGTAATCACCTAATTAGTAAGATTCATTTATCTATCTCACGAAACTCAAATAAGGCTGACGCCCCTTATATAATAAAAGATGAAAACTCTCGTAATGGTCTCTACAATGGCAAAAAAAAGATTTATAGTCTGATTTTACGTCATGGTGATATATTAACTCTAGGACCACCTGCATTAGCTGATACTGTTAAAGTTCGGTATATTTATCCTCCTGCGTGGTATACTCAAGCCTTTCGTTATAGTTTACTTGGTATTTCTGGATTCACTGCTTTAGTGAGTTTAATTATTCTACTTGAATGGACAAAATTTCAGGTATACCCTCTACCTAATCCAATTACAGGCCCAGTAGTTATCTATGCTCGTGATGGACAAACACCTCTACGTCCAGTTTATACAAACTCCCATTATGAATTGGGGCGGATATCTAAATTTTCTAAATATTTACCAGACGCAGTCATTGCTTCTGAGGATAGTCGCTTTTATTGGCATATCGGTATAGACCCTATTGGAGTTGTCAGGGCAATATTGACAAATTTACGTTCAGATGGTAGACGCGAAGGAGGTAGTACAGTTACTCAGCAGCTAGCAAGAAGTATATTTCGAGATTATGTAGGCACCGAAGACTCTGCCAGCAGGAAAATACGAGAAGCGATAGCGGCATTAAAATTAGAAACTTTTTATAGTAAAGATGATTTATTATTAGCTTATCTAAATAAAGTCTATTTAGGATTAGATTTATACGGATTTGAAGATGCTGCAAGATTTTATTTTGGTAAAAGCGCTCAAAACCTAACTTTATCAGAAGCAGCAACATTAGTAGGAATATTACCAGCACCTAATATTTTTAATCCAGTACAAAATTATCAAATAGCTATAGAAAAAAGAGATGGGGTTCTTTATCGAATGCTTAGTTTAGGTATGATAGACCAACAGGAAGCAGATAGAGCTAGGCGATCACTCATAGAAATTAATCCGAAAGCTATAGAAATTATCCAAAGTACAATAGCACCTTATTATTATAGTCATGTCTTTAGTGAACTAGAAAATTTACTAGGAGAAGACCTAGCTAAAGAAGGAAATTTTATTGTTCAAACGGCTTTAAACCCTGAAATTCAAAGCTATGCAGAAAGAACTTTGCAAGATACAATTAATCAAGTTGGTTCTTATGCTAGCTTTTCTCAAGGAGCTATAGTTACAATAGATTCAAGAAATGGAGAAGTCATAACTCTGATTGGAGGTGTAGACTACAAAAAAAGTCAGTTTAATCGAGCTACTCAAGCACAACGTCAACCAGGTTCTACTTTTAAAGTCTTTGCTTATGCCGCTGCTATAGAAAAGGGTATACCACCAAAAAAATTATATTCTTGTAGTTCCTTTGGGTGGATGGGTCAAACTTATGAAGGTTGTCAACGGAGTAGTGGTAATAGAAATATGTATGATGGCTTGGCACTTTCTGAGAATGTGGTAGCTTTGCGGGTCGCTCAACAGGTAGGTTTGGATAGAGTGGTAAAAATGGCAAAGGGTTTAGGAATTAAGTCTCAGTTAAGTGCTGTACCTGGATTGATTTTGGGTCAAAGTGAAGTTAATGTTTTGGAAATGACTGGTGCTTATGGGGTATTTGCTAATGGTGGAGTGGCCAATAAACCCCATACTATTAGAAAGATTATAGATAGTAGTGATTGTCGCGATCGCAATAATATTTACACTTGTCGCTGTATTTATTCATACATACCAGACACAAATTGTGAAAACCCCAAAGGAGATATTCAAGCAAACCAATCTATTATACAACCATATATAGCAAGTATTATGACTCAAATGCTCCAAGATGTTATAAGGCATGGTACAGGTCGTAGTGCTAATTTGGGATGGGGAGAAGCAGGTAAAACTGGTACAACTAACCAAGGAATAGATATATGGTTTATTGGATATATTCCTAACGAAAGTATGGTTACAGGGATTTGGCTAGGAAATGATGATAACTCTCCTACTTATGGTAGTAGTGAACAAGCCGCACAGTTATGGGGAAATTATATGAAAAAGGTTGTGAATAAGTAAGTAGATAGGCGTAAAAAAAATTTGGCTATATTAAGATTTGTATACTGACTTCAAGCTCCTCTACATAGTTGATTTGAGTTAAATTTTAATTGTTTTATATAGGGACAAATTTCAACACAGACATACTTTATGAAAAATCATATATTCAATATTTACTTGAGTACTTATCTACAGACAGTTATAAACCGTATCTGCCATTTTAAACTATTAAGACTTTACCATCCATCAATGGGTTAATTGTCATTAATACTATGACTTTTGTGAAGCTAGTTGCTGTAATAATTGTAATTTTTAGGCCACGATAAAATTGTGAATAATTTAATACTCTAGTACCAGAGCCTATTGGTGTAGAATTCTGTCGCCTTATTTACTTCTAATAAAATACTAATTTAATGTACTGTTAATACTAAGTTTTTAGGCTCTATCTTTTTCATTTTTTCCCAATATTCAAACCTCAAAATTTATACTTTTTCATTAGCTGACGAGGTTCTATATATAGTTTTTTCTGGTAAGATTGTATTTTTTTTAGGAGTTCCCGAAAAATCTCATACTGTTTCTAAAAAAAATTCTACATTTTATTTATTAGGAAAGCAGGGAATTAGGGTAGTAGAGAAGAAGTAAACATAATAATAATTTACATGAATTTAGGGAAAGATAAGTAAGTTAGTGTTGAAATTAGTACTATATAAAAAATGCAAATTTACCTCAAATTAACTCTATAGAGCAGGGTAAGCTCATCTTAATTTATATAAAATGTACTTGACAAAAAAGTAAAATATACAGGTGAGGAATAAAGAGACTAAGAATGAAAAAAACCAAGTAGAATGAAGGTTCTCACACATTAAATAATTAGCTCATGCCCCAGAGCTTTGCCTCTCTTTGACCTGCTGAAAAAAAAATATAGGTTCCAACAAAAAACAAAAGGAAAATTTACCATATCTTGATAAAATTCAAAACAATTTATTAGGCTATATTCTTGAAATTGAATATTCTAGAGTACAAACAACTCAAAAACACATATTCTAAGATATATTGTAGTTTTATTGAAGATATTCTTTTTCTTCATCCTAGAACTAAAAAGTAATTTTTGGGATTACCAAATAAATATTAAACAGGTGGTCTTCAACATTTGATGGCTAAACATATTAAATTAGAAGTACCCTCAGATACATTCAATAATTATTTTAAATTTACTGTTATTAGAAACCCTTGGGATAAAGTAGCCTCACAGTTTTGTTACACTCAAAAAACAAGACCTGATTTACTCAAATTACTTAATCTATCTAAAAATTATTTTGTTCAGGAATATCTCCACAAAATTTCAAAAAAAACCATGCTCAGTGGGAGGAAAAATATAAATTTATAGAGGATAATTTTGGGTAAATATTAGTAGATTATACCTATATATTTGATAAATTAAAGTTAGATTTTTAGAAAGTTATATGAAATCTTGATCTAAATCCTTGGCTATTTGAATTGCCTCATACTAATCAAACTGAAAGAAAGTACTATTCCCATTATTCTGATGATCAAATTAGGCAAATAGTGGTAGAAAAATATAAAACTTGTCTAGAAAAGTTTGGGTATTTATTTGAATTAGAAATTAAATATAAATTTGATAAAAATTATCAGATAAAAATATCTATTCCCATTTATAAAAAGTTTATGGTTCCAGTGATTAATAATTTCATTTCAAAAGCTAATAAATTAAAAAAAGAGGAGAAGCTAGATGAAGCGATCGCTCTTTACAAACAAGCTATAGAATTAAATCCCGGTTTTCCTTGGTATTACTATGAACTAGGAGAAACTTTAACAGAAAAAGGAGATTTAGATGAAGCAATAGCTCAGTTTTTTCAAGCTACTAAAATTAATCCTAACTCTGCCTGGTTTTGTTATGAACTGGCAAAAGCTTTACAAAAAAAAGGTGAGTTAAATCAGGCAATTAATTATTATAGACAAGCTATTGAAAGTAACCCAGACTTTTATGGATTTTACAATAGTCTAGGTTGTTGCTTTTTCCAGAATAAAAATTATCATCAAGCTATAATTAATTTTTTAATCGCACTGGAATTAAACTCCAGTTCAGTAATTAGCTACGAATATTTATATCAAGTATACTTACAACTTGGTTTGACTAAAAAATGTATTGATAATTTGTTTGGTAGATTTAAACAACCTAGTCAAAAACCTACTTTAACTATTCGCATAAAAGAAAAATCTGTCAATTCAAAACAGGAATTATCGAAAACAAAAATATTTGGAATTGGTTTAGGAAAAACAGGTACCACAACTTTGGGAGCTTGCTTAAATAATCTTGGATATAAACACTATGGTTGGTATACTTTGACTAATCACAAACTGCTTTACCAAATTAAATTAGATAATTTTGATGATGTTCATAGAGTAGTCAATCAATATGATTGTTTTGAAGATTATCCGTGGCCTTTGATTTACAAATGGCTCGATCAAAAATACCCTAATAGTAAATTTATATTAACCATAAGGAAATGTTCTCAAACTTGGTTTAAAAGTTGTTTAAATCATTATTTTCGACTACAAGATAGAGCAGCTTATCTCTATGATTTAATCTATGGTTTAGGTCATCCACAGAATTGTTCAGATGAGTATATAAATTTTTACGAAAGTCATAATCAACAAGTTATTGATTACTTTCAAAGTAAACCGGATAAATTACTGATAATTTGTTGGGAAAAAGGAGATAGTTGGGATAAATTATGTGGTTTTCTCGGAAAAACAGTTCCTGAAATTCTTTTGCCTCATTTGATGAAAAGTCAAACTAATTAATCAAGGATATATTTTTAATAAAATTGCTACAGGAGATTTAATGATGCAGGGAGATTAACTCAAATATGAGGGAAAGTTAGATTCGCGTTTCGCTGCGCGACATGAAATGCGGGGCATGGTATTAGCTATATCCCTCTCTATATAGAACCACTAAACTTATTTTTTACATTGATTTTCCTTTCTGCAGCATTCCTAATCCCTGAGAAACTATACTATTTTAGTTGAATAAAAAGTCATGCGTATAGGCGAACTTAGCCTTATAGTCTTTATAATATCACAATTTTTGTGGGAATGCAGCGGAAAATCTTTTGGCGCGCGATTTTTTGGAGCTTCAGAGAATGAATATATTGATGGCTTTCCACTGAGGAGGGAGGGATGGAAATATTTTAGTGGGTAAAATCCAGCATATTTATGGGTGCTTCACAACATGAAAATATTTCTGGTGTTGCTCCTTGAGAAAATTCTTCAATGTTCTGTTATCTCTGAGAGTGAAAATTTAGTTGAATAAAAAGTCATGCGTATAGGCAAACTTACCCTTATAGTCTTTATAATATCACAATTTTTGTGGGAATGCAGCGGAAAATCCTTCGGCGCGCGATTTTTTTTGGAGCTTCAGAGAATGAAAACGTTGATGACTTTCCACTGAGGAGGGATGGAAATATTTTAGTGGGTAAAATCCAGCATATTGGGTGCTTCACAACATGAAAATATTTATGCTGTTGCTCCTTGAGAAAATTCTTCAATGTTCTGTTATCTCTGAGTGTGAAAATTTAAGTGTGAAAAGTTAGTTGAATAAAAAGTCATGCGTATAGGCAAACTTACCCTTATAGTCTTTATAATATCACAATTTTTGTGGGAATGCAGCGGAAAATCCTTCGGCGCGCGATTTTTTTGGAGCTTCAGAGAATGAAAACGTTGATGACTTTCCACTGAGGAGGGATGGAAATATTTTAGTGGGTAAAATCCAGCATATTGGGTGCTTCACAACATGAAAATATTTATGCTGTTGCTCCTTGAGAAAATTCTTCAATGTTCTGTTATCTCTGAGAGTGAAAATTTAGTTGAATAAAAAGTCATGCGTATAGGCGAACAACCCCTTATAGTTTTTATAATATCACAATTTTTGTGGGAATGCAGCGGAAAATCTTTTGGCGCGCGATTTTTTTTGGAGCTTCAGAGAATGAAAATGTTGATGACTTTCCACTGAGGAGGGATGGAAATATTTTAGTGGGTAAAATCCAGCATATTCATGGGTGCTTCACAACATGAAAATATTTCTGGTGTTGCTCCTTGAGAAAATTCTTCAATGTTCTGTTATCTCTGAGTGTGAAAATTTAAGTGTGAAAATTTAGTTGAATAAAAAGTCATGCGTATAGGCGAACTTACCATTATAGTCTTTATAATATCACAATTTTTGTGGGAATGCAGCGGAAAATCTTTTGGGGCGCGATTTTTTTGGAGCTTCAGAGAATGAAAACGTTGATGACTTTCCACTGAGGAGGGAGGGATGGAAATATTTTAGTGGGTAAAATCCAGTATATTTATGGGTGCTTCACAACATGAAAATATTTCTGGTGTTACTCCTCGAGAAAATTCTTTAATGTTCAATGATAAATTACTGATAAGTTGAGAGGAAAGAGATTGTTGGGATAAATTATGTAGTTTTCTCGGAAAAACAGTTCCTGAAATTCCTTTGCCTCATCTGATGAAAAGTCAAACTAATTAATCAAGGAAATATTTTTAATAAAATGACTACAGGAAATTTAATCATACAAGGAAATAAACTGAAACGTGAGGGAAAGTTAGATGAAGCGATCGCTCTCTATACACAAGCTATAAATTTAAAGCCAGACTTTGCTTTTACTTATTATGAATTAGGGGATGCTCTGGAAAAACAAGGTAATTTTGCTCAAGCCATTATTGAATATGAAAAAGCTATTGAACTGAATCCTAATATAGATTTTTTTCATCAGAGTCTGGAAACAATTAAAAGTAGGAAACTTGAGCAAAATATTGATTTGACTTCCAATCAAATTAACTCAGATTTTTTGGTTGTGGGAATTTCCATGATTAAAAACGAGGAAGACGTTTTAGAAACTTTTATTCGTCATAATTTGAACTATCTTGACTTTTTAGTATTAGCCGATAATGGTTCTACAGATAATAGTAGAAAAATCATTAACAAACTTATTCAAGAAGGTTTCAACCTTTGTGTAATTGATGACTATAAAATGGCTCATAATCAAAATAATAAAATGACAAATTTCTACAGAAGAGTAGCTACATCATTATTTCCAGAATTTATTGTTCCAATGATGCAGATGAATTAATTCAGTCACCATCAAAAGAATCATTTATTAATTCACTTTCAGTCATTCCTAAAAATGGGATAGGTATTTATCCTTGGAAAACCTATATTCCTGAACCTACTAATACAAGTCATTTACTATCAAATTTTAAACACAGAAGAACAAAAGAAAATCCACAGTATTTTAAAATTATCCTCAAAACTAGCCGTAGTATTAATTATCAACTTAAAATCGATCAAGGTAGTCATGGAGTAACAAGCAAAAATGGCGATATACCCAGTGTTGAATTATCAGATATTTGTCTAGCTCACTTTCCTATCAGAAGTGTTAATCAACTTTTCAAAAAAATTTTACTAGGATGGTTAGGTGTGCTAGAAAGATTTAAAAGTAGAGATACTAAAGGAGAATGTTATCAATGGTATGACCTATATATAAAAATTATGCGAGGAGAAAAGTTTTCTAACTCAGACCTAACATATATAGCTCTTAACTACGCACAAAAAGTTGAGGTAAAAGAAGATTGTTTAAACCATGTTGAATTAGAACCTCCTACCATCAAATCATCGCAACTTTCTTATTCCGATTTAATAGCTAAAAATGATTACCGGACCAATGTCATTACAACTATTATTAAATCTTGGGAAAATCAAATTATAAAAATCCCTCCTTTAATTTCCAGAGAAGACTTAATTCCCTTCAGCGAATCACCTACTTCCCCATCAACAGATAATCATCAACATGGCGTCTTTGAGCCAAATTTTCACTTAGAAAAATTATTTATTGATATTCCACCATTCGAGTATATTTATCAGAGATTTTTGCCAGAAAATATTCTTGATATTGGCTGTGGTGTAGGTCAATATCTGAAAATTTTCAATAAACGAGGAGTTACAGAAATTATCGGTGTAGATGGTTTTATCCCACAACAAAGTTTCTTAAATTAAAATCAATATATTTGCCATGATTTAACTCACCCATTAAATTTACAACGCAAATTTGATTTAGTTATGTGTTTAGAAGTAGCTGAACATTTACCACCAGGCAAAGAACTTAACTTGATAGAAATATTAAATAATCATGCCTCCAATATTTTGATATTTTCAGCAGCAGAAATAGGTCAACCAGGAAACGGACATATTAATTGTCAACCCTTTGAATATTGGGTTGACTTATTAAAACAAAACTGGTCGCCAATGTTAACTGAGACATTATTTTTCCGATGTATCTCTAGTTTTTCTTCGTTCAGGAGAAACCCTATCGTACTCCAGAAAAAAACAGAATTAACCTCAGAAAATAGTTCTTTAAAATCTTGGGATAAATTAATTGTCATATCTCAAATACCCTACAAATGGTACGGTCAAAAATCTCAAATTATTTCCGAGATTCTAGAAATAGATATACCTGATGATATATATTCTTATTCTACTAAATAGCAACGGAAATACTAATTATCAATCATTTAAATATTGGGTTTTCTTGTGAAAACAAGACTATTTTCCAATGTTGACTGAGACATAATTTTTTCCATATATCTCTAGTTTTTTTTAGTATAAACCAGAGCATACTTCAGGAAAAAAAATAGCTTAACTTCAGAAAATAGTTATTTAAAATCTTCTAAAAAAAATTGATTTTTATATCTCAAATACATCACAAAGAGCATACTTCAGAAAAAAATAGCTTAACTTCAGAAAATAGTTATTTAAAATCTTCTAAAGAAATTGATTTTTATATCTCAAATACATCACAAATTGTTTGCTCAACAATCTCAAACTATCTCCGATATTATAGAAAAATAAATGCCCGATAATGTATATCTTTCTTATACTTAATAGCAGCAGAAAGAAGTCAATCAAGAAATAGATATATTAATTGTCAATTCTTTGAATATTAGGATAAATTATTACAATCAGACTTGTTGCTCATATTAACTTAGAAATAATTTTTTCTATGTATCTCTAGTTTTTTTAGGTTGAGGAGAAACTAGAGCATAATTCAGCAAAAATCAGTCAACTTCAGAGAATATTTATTGAAAATATTGAGAAAAATTTAATTTTTAGATCTCAAATTATCTCTGATGTTCTAGAAAAAGGAATACCTGATAATGTATATCTTTCTTATGTTTAAGAGCATCAGAAAGAGGTCAATTAGCAAATGGATATATTAATTTTAAATTCTGTGAATATTGGGTTAACTTACTACAATAAAACTAGTTTTCAATATTTAATTATAGATAATTTTCCGATGTATCTCTAGTTTCTTTGTTCAGGATAAACCAGAGTATAATTCAGAAAAAAAACTAGTTAACTTCAGAAAAAAGTTATTTAAAATTTGTAAAAAAATTGATTTTTATATCTCAAATATCTCACAAATTATCTAGTGAAAAATATTAAATTATCTCTGATGTATTTTGTTTTTTATCAGTCCAGTAAAAATCCTATTGTACTTCATAAAAAAAACTCGAGTTAACTTCATAAGATAGTTATTTAAAATCTTGGAAAAAATTGATTTTCATATCTCAAATACATCACAAATTGTTTGCTAAAAAATCTCAAATTATAGTCGTTTTAATCAAGATTGAGACAAAAATTGAGGATAAGAAAATCAAGTCAACTAGAAACTACTTTTAACTATGCCTTAGAGTTTAGACTTAAGACAAAAAGTAATAAATTTTGTAGAAAATAATGGTATGTTTACCGAAGCAGCTCATATATTTGGGATAGAAATAGCTTCGATATCTAGATAGTTATCTCGCCCAAAATTGGAAGCAACTAAGGCAAAATATTGCCTAATAAAATTAGATTTGAAAGAATTAAAAAAAGATATAAAACCCAATAAATAATCGCTCCTTAGCAGACACAGATAAAAAAAATGGAGTTAATCCTAAAGCTATATTTTACGCTTTAAAAAGAATAAAATTTCCTTAAAAAAAACAACTTCGTTATAGAAAAATAAATAGAGAAGAACGAATAAAATATTATCAGAAACTACGAAATTTCATCAAAAAATTTGGAAGTAAAAGCCTTGTATTTATTGATTAATCAGGATTTTAAGATAATCAAGACTGTATTTATGCCTGGTTAAAAAAAGGGAAAAAAGTTGATGGTGAGCCAGAAGGAAAACGAGGAAAAAGAGAAAAGTTAGTAGCTGGGAGAAGAAAAAAGGAAAAAGATTTAATGGCACCAATTATATTTAAAGGAATCCTAAATGCCGTGAGATATGAACAATGGTTAAATTAAGATTTATTACCATCATTAAAAATTTCCAGTGTACTAATTATGGATAATTAACCAATTCATAGAAAAAAGGTTATTAAACAATTAGTAGAAGCAAGGGTCATCAATTACTATTTTTGCCAAAATGCTCTCCTGATTTAAATGACTAAGAACATGATTTTAGTGCATTAAAAAGAGCTAGAATATATTCACCTATAAACACATCTCTCGATGAAATTATTCGTAATTATTGTGCCAAATAGCGTCTCATTCTTATTTCAAATGACTATATCTCCGATATTCTAGAAAAATAAATACTCAATAATGCATATCTTTCTTATACTTAACAGCAGCAAAAAAAAGTCAATAAGGAAATGGATATATTAATTGTCAATTCTTTTAATATCGAGCTAACTTATTACAACAAGACTGGTCACCCATGTTGAATTAGACATAATTTTCCCCATTTTTTTTTGAGTATAAACCATAGCATAATTCAGAAAAAAAGCAGTCAACTTCAGAAAATAATTATTGAAAATATTGAGAAAAAATTGATTTTTATATCTCAAATATTTTGCAAATAGTCTGGTAAAAAATCTCAAATTATCTCTGATGTATTTCGATTTTTTATCAGTTCAGGAAAAACCCTATTGTACTTTATCAAAAACTCAAGTCAACTTCAGAAAATAATTATTTAAAATATTAAGAAAAATTGATTCCTATAAGGATAAGTTCAGATAACTATAATGAATCAGGAGATGTAAAAGTGACCATTAAATAATTTAAAAACTACACAGATAATTATCCAGATTCGGTTCATGGAGACCCAATTTACAGAGTCGCGCGCGAAAATAGAAAATTTACTTCATCTGAGAGCTATTTTATGGGAGCTATCTGCCGGTTTGTTGAGCACCCAAAAATATTGATAAAAAACATATGAAACAAGCTAAATTAGATAAAAGATTACGTAATCATATTGAGGGTCAACTTGGGCAATACGAAAAAAATATTTAGTCTAGTCAAAGTAATAGCAAAACTTTCTGAAACTTCCACAATTATGTACGCAATTACTTTTTTACTAATCAACCTTTCTACCTTCTTGCAAGAAACTTTTTTTCTTTTTTTACACTTTTTTTGTTTTGGTATTTTTTTTTAATTACTTAAAATTATATTTTCATTAAAGTCTAATAATCAATATTTATTATTTTTTTTGAATAAGAAATAAAGCATTGTCTAATTTATTCAGCAAACCCTATTTAGCGCTAGCTGATTAATTCTAAAAGTATGACATATAAAGCCTTTAGGATTATTTGCTAAGCAAAAAGTACCAGCTTTTTAGTAGTTTAAGCTCATCCATGGATCGGATTTCGCACGAACCATTACAGAAAAATCAAAGGACAATTCTTGCTAATACCTCCTCGTGACCGTACCATTAATCCTAACTTGTGACTTACTATTCCCTACTTACCACTCCCTACTCTCTCCCTAAAAATTAAATCAGAAGGGTTAAAGATAAATTTTAAAAATCTACTTTTTATAACCTGTGGAGAAATTTCCCCATTCTTCTGTAGGGATGTTTTATGCAACGTCCCTAGCCACCTCTTCAGGGCGTTTTTATTCTCTATCTTACCCCTAATTAAGTGAGGAATCTAAAAATATTTTATAATAAGCGATCATGCTATTTTTTTCTCAAATGAGACATTGAGAGAGAAAAAAATATTAAACTGCCTTCAATTTTGGTAGTTATGCGATAGCTTTCTTTGAGAATAAAAATGCCCTGCCGACCCCCCTACTCCTTAAAAAGATCAAGAAGAACAAACCCTAGTTATTTTCGGCTTTTGACTTTGTGGATTTCCTACCACGAGCAGATTTTTTACTACTAGCCTTAGCATGCAAAAGCTCTAGAGCCTTTTCCCAAGTTACATCCTCAACAGACATATCCTTAGGCAAAGAAGCATTAACCTTACCATGCTTCACATAAAGTCCATATCGACCATCATAAACACCTACTGTTTCTCCATCTTCAGGATGTTTACCCAAATCTTTGAGGGGAAGTACAGCTTTAGCACTACCTCTCCTCGATCTTTTCGGTTGAGCTAATAACTCCAAAGCACGTTCCAAAGTAATAGTCAAAACATCATCCTTAACCTTTAAAGAACGATAGTCTTTACCATCCTCCTTTCCCTGGTCGTGAACGATATATGGGCCAAAACGTCCTAAATTAGCTTGAATTTTGCAACCAGTTTCTGGATGAGTTCCCAAAGTACGAGGTAAAGATAATAACCCTACCGCTAGATCCAAAGTTACATCCTCCATATTGACACCCTTTGGCAAAGAAGCTCGCTTTGGTTTCCTCTTACTACCCTCAGAATCATCACCCAACTGCACATAAGGACCGTAACGACCAGTCATTATATAGATAGACTTATCTTCTTCTGGATGAATTCCCAACTCCTGCGGACCCTCTGTTTTTTGCTTCAACAGTTTCTCTATTTGTTCTGGGTCTAGGTCTGATGGAGTTAAATCTTCAGGAATAGAAGCTTTGACTATATTCTCACCATTTTCTGCCTCAATATAAGCACCAAACTTACCAATACATATACGATAAGTCATCTCTGAATTAGCATCCAAATTATCTAACTCAATAGTTCGGGCCAACTTAGGGTCAATTTGATTTTCCTGTTCCTTGATTTGAGTATCAAGTCCACTTTCCCCAAAATAAAATTTTTTAAGGTAAGGTACCCACTGAGCTTCACCCATAGAAATGTCATCGAGGGTTTGTTCCATACGGGCAGTAAACTTGACATCTACAAACTCAGGAAAATGTTTTTCCAGTAAAGTTGTAACAGCAAAAGCAGTAAATGTTGGAACTAAAGCATTACTCTGGAGTTTGGCATAACCACGATCAACAATAGTACCAATAACAGTAGCGTAGGTACTCGGACGGCCGATACCTTCACTTTCCAAAGTTTTTACCAAAGACGCTTCGGTAAACCTGGCAGGTGGCTGAGTTTCATGACCCACTACTTCTATTTCTGTGCAAGCAGGATGGTCTCCCTGTTTTATAGCAGGCAATGGTACTTCTTGGTTTTCCAAAGATACTTCGGGGTCATCAGACCCTTCAACATAAGCCCGGAGGAACCCAGGAAAGTCTATCCGTTTTCCATTAGAACGAAAACCAGCATCTTCTACTTGTAAATTAACTGTAATATGGGTTTGACGAGAATCAGCCATTTGACAAGCTACTGTTCTTTTCCAAATTAAGTCATAGAGAGCAAATTCTTGATTTTTCAATCCTGTTTCCTGGGGAGTGCGAAAAGTTTTACCTGCAGGGCGAATAGCTTCGTGAGCTTCCTGAGCCCCCTTACTTTTAGTAGTGTATTGCCTAGGTTCAGAACTTAGATATTCCGGGCCATACATTTTCTCAACACAACTTCGGGCAGCAGCGATCGCCTCATCAGACAAATGTACTGAGTCTGTCCGCATATAAGTGATAAAGCCCTGTTCATATAAATTTTGGGCTGTCCGCATTGTTTGCCTAGCACCCATTCGTAGTTTGCGGTTAGCTTCCTGTTGTAAAGTAGAAGTAGTAAATGGTGGAGATGGTTTACGTCTAACAGCTCGTTCATCAAAACTATTAACAGTCCAAGGCTTATGTTGCAGTTGTTCTTTGAGAGCTTCTGCATGAGCTTCGTCCAATAAAATAACATTACGACCTTCAACTATTTTGCCTGTATTTTCATCAAAGTCATTACCAGTAGCTATTTTTGTCCCCCCAAGGGTCACAAGTTTAGACTCAAATGGAGTTTTTTCTTGTTCTAAACTAGCCTTTAAATCCCAATAACCTCCTCGCTTAAAAGCCTGACGTTGGCGTTCTCGGTTAACCAAGAGTCGGACTGCTACTGACTGTACTCTACCTGCAGAAAGACCTCTGGCAATTTTTTTCCAAAGTACAGGTGAGAGAGTATAACCGTAGAGGCGGTCTAGAATACGACGAGTTTCTTGTGCCCTGACTAACTGCTCATCTATGTTACGACAATTATCAATTGCTCTACGGATAGCTTCTGGAGTAATTTCATGGAAGACCATCCGTTTAGTAGGAACTTTTGGTTTTAGTAGTTGCAATAAATGCCAACTTATACTTTCTCCTTCACGGTCTTCATCTGTGGCTAGAAGTAATTCATCAACTTCTTTCAGAGCATCTTTGAGTTCTTTGACAGTTTTCTTTTTGTCTTTGGGGACAACGTAGATTGGTTCAAAATCTGACTCTACATTTACCCCTAACTGTGCCCACTTTTCTCCTTTGAATTTTTCTGGTATTTCCTCGGCAGAAGGTGGTAGGTCACGCACATGACCCATAGATGCTTCCACGCGGTAGTCGGAGGGTAGATAGTTGCGAATGGTGCGGGCTTTAGTCGGAGATTCTACAATAACAAGGGTTGACATAAGACCTTATATTAGGTATTATAAGAGATTAATTTTTGTATGTTAGTATTAGATTGAATAGATAGTTATGTACCTGTCATAAATGTTTCGGGTGGTTGATTCTATAATTTTTGCTTTGATTTGGCTTTACAGCATAAAGCTTTTTTATTCCACCCAATCTTAATTTTTATTTCTGGCAAAACACGTATTTGATAAACATTAACTTTACAGCTATCCTTATTAATATCTGCTAGCATAATCAGTATTTAATGTCAATAGTATGGATATCTTGTTGCTCAAATTAAAATGAAAGCTTGCATAAAAGATTGCTGCTAGCTTCTCTCTGTATCAGTTTAAAATCCTAAAGTTTGGGGAATTATTGCTTGCTTAGAAGACAAATATCCTTAATTCAATTATCGGACAAGAAGTGGATAAGCTAAAAAAATCATTAATACTTCTATAAACTATCAATAACTAAAGTGTATAGTATAATTACTATCACGATAATGTCTTACTAAGAAGGCCTAAAGTAAATCTATAAAGGCCTAAGGTTAATACCTAAAGTTATTTAAGTGTTCTTAATTTATCTGTAGAGTTTATGTTATTGTAATAAATCTGTGTTATTCTTCTAGGAATTAAGTAATCGGCCCTATTTTGTAAAAAATTTGATTTGCCTGAAGTGAAGCTCCTAAAAATTGATATGTCATCTAAATTATGAATAACAAAGTCCAATTAGAATATTATTTTTAACAATTTTTAACAACTACTTGAATTTACTAAAAGAAAATATTCAATAACTCAGACGTTATAGTTATGACTATCTCATTTGTAAGTACAACAAAAGCTGCTTTTTTACTGAATATATCTACAGGTAGATTAAGAACTCTACTAAATCAAGATCGTGTTCGAGGTGCTCGTAAAGCCAAAAGGCTTTGGCAAATTCCGCTTAACTATCGAGGAATGCCAGAAATTAAACCAGGTCGTCGTGGTCCTCAAGGAACTTGGAATAAATTTCAACGCCAAGCTAAGACTATCATCCATGTTCTGCGAAAGACTATAGACTATAACCGAGACAATGGAACCTCTTATCCAGCAGTAGCGGTGAAAGTAGGAAATAAAAAAGATTATTGCCACGCTTTAAAAATTGATGGTTCTTGCCAAATAATTTATCAGCCCCATCAACCCAATAAAAGTCAAGCCGGAGGTGCCCGTCTGTGGATTGAAGTGGAACCGGAAAATATAGTAGAACGAGTATACTTCAGTGATGGAGATTATGGTCCGCCACCAGAAGTTCTTCAGCAGCGAGCCAGAAGTAAAGAGAAAAAATAAAACATGAAAGATTATAGCAATTGAAGCAAAGGTTAAAACCTCAACTTAACAACATAATCAACTCTATTTCTAAAATCTCCTATTGTTTCTTCTGACTTTCTGAAAAGGTTTTTAATGGAAAACCAATAATGTTCTATTTCATTTAAGTAAGGAGAATATGGTGATGAATGTTCAATTTCACAATCCACTGACTCAATTAATTCTTGAATTTTTGGGGGCTTGTGAAAACTTGTATTGCCATAAAATATTCATAGTAGTCATGTTTTTATTTATCGCAACAATTTTTATGTTAACCATTTTTCAAAAACTAAATGGTTATAAGAACTATCAAACGAATAAAGCAATTAATTTTCCCTGACACAAACCACTTATAATACTTATCCTCAGACTTATTCTTCCTAATTGTCAATCGTAATATATTTTTCCAATTGAATTCCATCGATCAATCACCATAATCTTCTCACTTTATCAATTTCAGGATTTATCTATATATACTAAATATTATAGCTTTTTTTCGCGGATTTTTGTCAGAAATTCAATTCTATTCTCTTCATCTGTTTCTCTGTAACTGTAATTTTTTGTATGTGGCAAATTGTTTTTTTTAAGGCTTTACCTATAGTGTGTTTGTGCAGCAGAAGGTCGTTCTATCGCTAACTGATTCTAGCCATAAAGGGTGACATTTTTTTTTGAGTTTTACTACCATTAATGTAGACCAATTCTTGCTCATTATTCTAAATCTGGTATTTTAGGATTATCTCCTTTTTTATCATCTGTTTTTGCTCTTATATACCTAGTTTCTATTCTTCCAAGTAACTAAATATTAATGGTATTACAACTAATATTAAATATAAAACTTGTTTCAGTTTTACTCATCCCATCATCAATTACATTAATAACTTTTTATCAATAGTCGTAGGTATAAGGAACATGCATAATCTTTTTCAGATAATTTTTCGAGCATTATTTCTATATCTTTACTTCGACTACTACTAAGATAAACAATTACCTATTTCCCTCACACATATTATAATCATAATTTTGAGTAGACAAGGAATGTTAAAAATCTTTGAATCAGGACTTGGGCAAAGATACTATATATATAGGGCATGACAATTTTGACCACCTGCACTATAGCTTTGTGTGATACGGATAACTCCACGGGAAGCGAACGCTTAAATATTTTATTTTATTCAAAAAAACCTTCATTGATTCAAGTTAAAATTTGCTTCATTATAATTAAAAGATATTTTCATTATGAGATAAGACCAATTCAATAATAATTAGTGGCTGTTCTTGAATGAATACTTTTTATTATTTAAAAAGCAAATATTTTTAATAATTTCTATACGCTTGATTGCACAAGCAATATATTTTTTTTAATTATTCGCAGGCGATATTGGCAAAATTATAAACTTGTTAATTACTTAATTCTGTGGTGATTTTTTTTAATGTTCTATTTAGTTTGAGTTAAAATTATAAATCATCAGCGTGATGATTTATTTAGATTCTTAGTGACAATATATTCTGCTGAAGTTGGCAGACACAGTATCCCAAAATATTTTTAATTTTTTGTCTTGTGGAAAACCTTTGATTTTCATTCTTTTTCCCAAGACTTTTTCAGTCTCATTCCAATTTAATTATTGAATCTTTTTGTATTTTTATACCCCGCCTGTATCATAAACTAAGCGATTACTTTTTAAATGACATTAATAGATATTTTTTTCTAAATTATCTATTAATGTCATTAATCTTTGTATTGTATACTTACTATCTATTAATACAGTTTGAAATAGTACTTTTTTTTGTTTATAGCATTAAGTACTATTTTTTTTTACATTCATTATCTATATGATCTATAGCAATGCCCATAGCTATGAGGTACAGTAACAAGAATTGTTAAACCAATTGCGAATATCTTGTTGACTAACTTTTAATATAGTTGAGGTAATGGCATCAATTAAATCTTTATAATTTCTTACTTTAACTATTCTTAGAATAGCTTTCATATTTGACTAAAAGTTTTCAATTGAATAAAAATCAGGTGAATAAGAATGTAAAAATAACAGACTAGCTCCAACTTATTCAATAACTTCTCTCACCATTTAGGAGAAATTAATTTTCCCATTTTCCATTACAACAGGATCTCCTTTTCACAGTCATGGAAATACTTATTTAACAATAAAAGCCTCAAAAGTTACTCCATATAATGCTCCATCAATATTTATTTTTGCCAAAACTTTTTCTCAGGATATAGCTCCTATGATTGAGATATTTTTTCCTAGTTTTTGAGGTTTTATCCTCTGACTCTTTTCCCTTTTAAGGCTCTAGCATATAATCAAAGCATTGCCAAATTTACTCCTGATTCATCTATAAAGACTAAATTATTGATCTTTATCCCTCTAACTATTTCCCAATACTCTACTCTCTTATATTGGAGTTAAACATTTTCTTTTTCAGGTACATACAATGTTTTTTTTGAGACTGTAGTTTAACTTTTCAGTTATCCAATGATTGTACTTTTTCCTACTTTTACTCCTGTAGCTACTTCGATTAATTCTCATAATTTCTCATTAGTTGCATCATTATTTTTCCCCATTATTTCTACTAAGATTAATAATTCTTCACTATTGAGCTGAGAAGGAGGACTTCCTCCTTGAGGTAAAGGTTTAATATCTCCAGTTTATTGATATTTTTTGGTTAAGGTTTGAATAAAATTTTGGCTGACTCCAAACCTATGATCCAGCTTCCTTATAGACATTTTTTCGGTAGCTACAAATTTCTACAATTTTTTTTCTAAAGTCTATAGAATAAGGTTTCATCAGTTTCGCGATCGCTATAAAAATTAGCCCTACTAGTGTATCTTATGACTATGGGAAATACTATATTTTTGTTTTTTTGTTTTCTTGTCAGTATCTGGTTCATAAATCCTGTAATCTATAATTCATAACTGTTCAGTTTGAGAATTAAAATATATACAATTAACTATTCCTATACCACGAGCTTCGTAGCTGAGAGAAAGCAAATAACTGTATGTTCTTTACCACTTTATTTTTATCGCGTAAGTGCTTCTAAGAGAGGAGGTACGCCATCAATTTTTAACCCATACTTTTTATTAATTACTGTGTCATCAAAGATTAAATATACTGATATACCTGAAAAAAATTATTATTTAATATTTCGTCATAAATATTGTGAATTTAAAGACTATTTTCTTAAATAATGGTTTATTTTATCATGTCTAATATTTTTACTTTGCTGTTCTCAAGTTTGTTTTTGTATAATTTGTGTGATATTGAAGTAAATATTAACTAATTACAACATAATTAAAATCCATGTTTTTTTGAAACTAATATAATTATGCCATTGCTGTCTAACTATAAAATTTTTTTAGCAATTCAATTTAACAATTTATAATCTATAGCAATCCTAAATCATTTATGAAAAATTACTAGTATTTTGAAAAATAGCTCTAATCACTGTTAATTATGGTTTCTCTCTTCAGCATAAGTATCTTATAGCTACCGATCTCTTTCACTTTTCAGATAGGATTACTATATTTGTTTAGACATATTCTTTTTTTCTTACTAGATAATATATATCAAAAGTATAGTTTTTTAAATTAAGATTAAGACAAAAATTGAGTTGAATAAAATCAAGTCAACTAGCAACTATTTTTAACTATGCCTTACAGTTTATACTTCAAAAAAAAGTAATAACTTTTGTAGAAGATGCTGGTATTATTACCAAATAAGCTGATATATTTGGGATAGGAGGAGCTTCGATATATAGATGGTTATCTCACCCAAAATTGGAAGCAAGTAATGTGAAATTTTGTCCAATAAAATTAGGTTAGAAAGAATTAGAAAAGGTAAAATTTATTCAAATAAAATTAGATTGGAAAGAACTAGAAAAGGTAAAATTTATTCAAATAAAATTAGATTGTAAAGAACTAGAAAAAGATATAAAACCAAATCAATAATTGCTCATTAGCAAACAGAGCAAAAAAAAATGGAGTTAATTCTATAGCTATATTTTATGCTTTGAAAACAATTAAGTTTCATTGAAAAAACAACTTTGTTATAGAGAAAGAAATAGAGAATAAAGAATAAAATATGATCATAAACTACGAAATATCATCAAAAAAAATTGGAAGTAAACGCTAATTATTTATTTATGAATCAAGATTTGAAGATAATTAAGACTGTATTTATGCCTGGTCAAAAAAAGGGAAAAAAGTTGATGGTGAGCCAGAAGTAAAACGAGGAAAAAGATAAAATTTAGTAGCTGGGAGAAGAAAAAAGGAAAAAGATTTAATGGCACCAATTATATTTAAAGGAACCCTAAATGCCGTGGGATATGAACAATGGTTAAATGAAGATGTATTGCCATCATTAAAAATTTCCAGTGTACTAATTATGGAGAATTAACCAATTCATATAAAAAAGGTTATTAGACAATTAGTAGAAGCAAGGGTCATCAATTACTATTTTTGCCAAAATGCTCTCCTGATTTAAATGGCATAGAACATGATTTTAGTGCATTAAAAAGAGCTAGAATATATTCACTTATCAACACATCTATTGATGAAATTATTCGTAATTACTGTGCCAAATAGTGTCTCATTCTTATTTAAAATGACTATAATATCTATAAAGTATATCTATCCGAAAAAAACTAATTTAAGTAATTGACAATTCCCGAGTTGACAGTACGCTATATATAGCGTACCTGCGTAATTTCTGTGAATGTGACTACAGGGACTATCATATTTAATAGGCAAAGGAAAACAAACTGCAAGCCTTTAATCTGAACTAAGGTGACGATAGTTTTAATAGAATTAGTATTCACTAGATTTGGAGTAACAACTTTTGCCTCTTTGGCTAAAGAACTATAGCCAAAGCTGACATTTAAGGCCATGTACCGAGAGTAATTAACCCTACCTCAAATTACCTGACCTAGAAAGTTATTCCCTAACCAAGAGGAGAGGAATTTAACCTCCAAGGAATTGGGAGTTATCATCTCATATCACCTCTAGTAATTATTAGAGATATCGGCTATGTTATACTAATTTCATAAACTTAAGCTACACTTTTAGAAGTAACCTATTATAGAAAATGTCCCCATGTCAGGAGTAGTAAAAATTGAGATAAATGAATCGGTAGAAACTCTCAAAAAACTTTTAAAAAGTGCGAGTACAGCTCAAGAAAAGGAAAGACTTCAAACTATTTACTGGTTGAAAACTCAAACAGTAGAAACAGTAAAAGAAATTGCGATAATGTTAGGACGCAATCGAGTCACAGTACAAAAATGGTTAGGGAAATATCGTACAGGTGGACTGAATCTTTTACTAGAACCAAAGAAAAATCTAGGAGGGAGGCCAAGTTCAATTCCACCAAATGTAATCGAGAAATTAGAAGCAGAATTGCAAAACCCGGAAGGTTTCCAAAGCTATGGTGAAATTCAACAGTGGTTAACGACTTGTTTTGACATCGAGCTGTCTTATCGAACAGTTCATCAATTAGTCAGATATAAATTAAAAAGTAAATTAAAAGTTCCACGTCCAAATCACATAAAACAAAATAAAGAAGCTCAAGAAAACTTTAAAAAAAACTCTCATCTCAACTAGAAGAGAAAATTAAGTTAATTAATAAATATTCGGAAAATCAACTGCCAATTCGCTATTGGTGTCAAGACGAGACTAGAATTGGATTAAAAACTATAACAGGTAAAGTCATTACTGCTTGCGGTGTTAAGCCCATTGGTTTATATCAATGGCTATTTAAATATCTATGGCTTTATGGTTTAGTAGAACCAAAAACAGGAGATTCCTTTTTTTATGAATTTAGTCATCTAGATACTCCTTGCTTTGAAAGATTTTTAGAGCTTTTTTCTCAAACATATCCTGAAGAGATTCATATTATTCAACTAGATAACGGGCGAGGGCATCTAGGGAATGATTTATCTATCCCTGATCACATCATTTTATTATTTCAACCTCCTTATTGTCCCGAAGTTAATCCCATTGAAAGACTGTGGAAAGAGGTGAAAAAATTCTTGAAAAATCGAGTTTTCGATTCCTTAGATTTCTGACGCAGAATCCTGAGAAATATATTAACTGGATTTAGTCAAAAAGATATTGCTTCTTGTACAGGATATGATTTTATTCTTGAAGCATTATGTGTAGTCGGACTTTAGGAAATTGGTATTACTTATGGGGTTCTTTAGCCCAAGAAGTCGCACTCAGCAAATCCTAAATAAAGTGATAAAGTAGGTGAAAGTCTAGTAAAGTTTCTATATTTTTATAGACTATGGACTGTGGCAATGAGAAAGCTATCATTCCATAAAAAAATAAACGTTTTACGAAAAACTGCAAATTATTCTGATGGTAAAACTATTGAACAAAATACTAAATCTGGAGAAGCTCCCAACTTTAATAGTATCTCTACTATTACTAATTTTGGCAACTATAATACCAGTATCCTCTGTATCTGCAACTGGAGTTTATCAAATGCCCAATTTAGACACAGGTAATCGTACATTTATTGTTGATGATGCAGATGTTCTCAGTCGAGTTACTAAGAATAAACTAAACAATACTTTAGAAAATTTGGCTAATTTGACTGGGAATGAAGTTAGATTCGTTACTATCCGTCGCCTAGATTATGGTGAGACTGCCGATAGTTTTACTGAAAAATTATTTGACAAATGGTTCCCTACTCTAGAAGCAAAAGCTAATCAAACCTTAGTAGTATTAGATACTCTCACCAATAATGATGCAATTCGTATAGGTGATGCAGTTAAAATATTTATGTCTAATGATATTACTCAGAGTTTAGTTAATGAAACTATTCAAGTACCTATTAGAGATGGTAATAAATATAATGAAGCTTTCTTGGCAGCTAGCGATCGCCTAACTGCTGTATTATCTGGAGAACCAGATCCAGGTCCTCCGGATATTAAAGATGAGCTTTCAGCACAAGTAGCAGCTACTTTTAAATCAGCAGAGGAAACTAATGATCAAAGTGCAACTGTTTTGGTTGTTGTATTGTTAGTTATTGCTACAGTTGTACCTATGGCTACTTATTTCTGGTATCAAAGCTTTTCTGGCTAGTAATTCAAGAAAATAGCAAAAGGTTTCATTTATACATAATTTCTGTAAATTGAGTTAATCTTGAATATATTCTTTACCACTTAATAAAGCAATTTCAGCACGGACAAATTCCCGCCCTAAATAAGCAGCATGATCTAACATTGTGATGTGACAAGGACGGGTTTCTTCAAATATTTTGACACACATTTCTTTTGCGGTTTTTGCAGTAAATATTGCATTTTCCTGACGTTCTACTTTACCTTTAGCAGGAATAGGTTTTCCTGTTTCTGGATCGATAGCTAGACCTCGGCTGTCAATTATATTAGTAAAATGTTTTGCAAAAATAAGACCAGCTTTTTTGTCGATGAAGATAATAAAATAACCACCAGGGTCTAGATCTATGTGACGTTTTGAAAGCTTTTTATCAATTGTATTTAATTCTTCAAAGGTGATATTCATAGTTCAAATTTAGAATTGCTTGTATTTTATTCTACATTTTTCTTGGTTGTTTAACTCAGTTATGGCATCTTAAAATTTATATAGCAATTCCCATAATTTTTTTTTCGGGCAATACAGTTGAGTTAAGATTTTTAAGGTTATATTCATAGTAAAAATGTAGAATTGCTTGTATTTTATTCTACATTTTTCTTAGTTGTCTAACTCAATTATAGCATTTTAAAATTTATATAACAATTTCCATACTGTTTTTTTTTCGAGCAATACAGTTGGGTTAAGATTTTTTTTTGCAATTTTGTAATCTGAACAGCTTATATCATAGTTCAATAATATAATAGCAGTACCTTGATATTTTTGAAGTGCCAAAATGCTATTAATTGTTCTTTTGGAGTAAGGGAAATATAAAGCTCTTGCTAAGAAAAGCTTTAATAAAAGATAGATTACTATCCACAGTTTATCAAAAGTAAAGCCTATATTTTATAAAGCTTTGATAATATTTTTATTTATGTTTTACTCACCTCAGTTTTGCCTTGCTCTAAAACGTATTGTGTTTTAGGGAGTAGAAAATAGTAGTTGCACCACATTATTTTCTGGTACAAACTGACTTTTCCTAGGTCATACTGCACAAATAAGATATTTTTCTGTCACAAAAATGTTTCGTATAAAAGATTAAAAAAATAATGTTACAAATAATCGGGGGTAAATTTATCGGAGAATTTAATCAGATTTCCCTTTCTATAAAATAAGCTATAGCAATCCGTGGGTAGGTTGCGACAAAATTCTATACTGAAAAAGTTTTGGGAAATTGGATATTTTACCATCTGCAAAAAACTTTAAATAACTTAACTACTTTAAAATAACTGCAAAGATAATAAAAATATCTAATAAATTTTTTGGCTTGTAACCAAATATCTTCAACAGGATTTTGCTCCGGAGCATTTGGAGCAAATGAGCGTACAGTTTATCAAGCATTCTTCTTCCGATAAGTCTTGATTAATTGTCATTAAATATTCTCTATATGCTTGAAAGTTATAATAAGTTACTCCATCCCAAAATATTGCCAATTTATTACCTGGTCTTTGCTTCTGCAAATATTTAATAAATTCCATAGTTTTTAGTATTTCCACTTCTTTAATTCTTGCACAATAAATTATTTAGTTTGATAGTCTAAAACTCGATAATAAAGTCTGTTTTTCTTTTTCATTTTTCATCGTAATTTATATTCTTTCATATGTTTTTACCTAAGTATAACCTAATATATCTCCCCATAGAAGATGACATTCATAAATCATAAATACTGTAAGCTTTTCAGCTTCTATTGCTGGTTACTATTTATTTAGCTAACAATTCCTCTATTTTTTTCTTTCAGCTTGTACTAATTTATCATTTGTAGCAGTTTTTGAATTTTTTTTCAGCTTATTTATGCTTCTTTTAAGAATTTAAAATAACTTTAGATATACTCAAAAAAAATCTCATATTGATTCTGTAAATAGCTTTTTTGACCTGATAAAATTAGGTAATATTGTTCCCTAAAATACTGATTTTTTTTTCTTCCTTTGCGACAGCCTTTAAGTCACCTTTTTCCCAATATATAGTCGTTTTAATTAAGATTTAAATAAAAATTGAGTATAATAAAATCAAGTCAAATATAAACTATTTTGAACTATGCCTTACAGTTTATAATTCAGACAAAAAGTAATAAGTTTTGTAGAAAATGGCGGTACGATTACCAAAGCAGCTCATACATTTGGGATAGCAAGATCTTCGATATATAGATGGTTATCTCGCCCAAAATTGTCAGCAACTAAGGTAAAAAGTCGTCAAAGAAAATTAGATTGGAAAGCATTAGAAAAAGATGTAAAACCAAATCCAGAGTCGCTCATTGTCAGACAGAGCTAAAAAATTTGGAGTTAATCAATCAGCTATATTTTATGCTTTAAAAATAATGGATTTTCCTTGAAAAAAAACAACTTCGTTATAGAGAAAAAAATAGAGAAGAAAGGATAAAATATTATCAGCTTTCCCTTGAAATTTTATCAAAAAATTTGGAAGTAAAAGCCTTGTATTTATTGATAAATCAGAATTTGAAGATAATCAAGACTGTATTTATGCCTGGTCAAAAAAAAGGGAAAAAAGTTTATGGTGAGCAAGAGGGAAAACGAGGTAAAAGAGGAAATTTAGTAGCCGGGAGAAGAAAAAAGGAAAAAGATTTAATAGCACCAATTATATTTAAAGGAACCCTAAATGCTGTGGGATTTGAACAATGGTTATACCAATTTCCTAAAGTCCGACTACACATAATGCTTCAAGAATAAAATCATATCCTGTACAAGAAGCAATATCTTTTTGACTAAATCCAGTTAATATATTTCTCAGGATTCTGCGTCAGAAATCTAAGGAATCGAAAACTCGATTTTTCAAGAATTTTTTCACCTCTTTCCACAGTCTTTCAATGGGATTAACTTCGGGACAATAAGGAGGTTGAAATAATAAAATGATGTGATCAGGGATAGATAAATCATTCCCTAGATGCCCTCGCCCGTTATCTAGTTGAATAATATGAATCTCTTCAGGATATGTTTGAGAAAAAAGCTCTAAAAATCTTTCAAAGCAAGGAGTATCTAGATGACTAAATTCATAAAAAAAGGAATCTCCTGTTTTTGGTTCTACTAAACCATAAAGCCATAGATATTTAAATAGCCATTGATATAAACCAATGGGCTTAACACCGCAAGCAGTAATGACTTTACCTGTTATAGTTTTTAATCCAATTCTAGTCTCGTCTTGACACCAATAGCGAATTGGCAGTTGATTTTCCGAATATTTATTAATTAACTTAATTTTCTCTTCTAGTTGAGATGAGAGTTTTTTTTAAAGTTTTCTTGAGCTTCTTTATTTTGTTTTATGTGATTTGGACGTGGAACTTTTAATTTACTTTTTAATTTATATCTGACTAATTGATGAACTGTTCGATAAGACAGCTCGATGTCAAAACAAGTCGTTAACCACTGTTGAATTTCACCATAGCTTTGGAAACCTTCCGGGTTTTGCAATTCTGCTTCTAATTTCTCGATTACATTTGGTGGAATTGAACTTGGCCTCCCTCCTAGATTTTTCTTTGGTTCTAGTAAAAGATTCAGTCCACCTGTACGATATTTCCCTAACCATTTTTGTACTGTGACTCGATTGCGTCCTAACATTATCGCAATTTCTTTTACTGTTTCTACTGTTTGAGTTTTCAACCAGTAAATAGTTTGAAGTCTTTCCTTTTCTTGAGCTGTACTCGCACTTTTTAAAAGTTTTTTGAGAGTTTCTACCGATTCATTTATCTCAATTTTTACTACTCCTGACATGGGGACATTTTCTATAATAGGTTACTTCTAAAAGTGTAGCTTAAGTTTATGAAATTAGTATTAGATAAACATTTATGACCATCATTAAAAATTCCCAGTGTACTGCTGCACGGATAATTCACCATTAATTACGAAAAAAAGTTATTATAGAATTAGTAGAAGCAGGGGGTCACCAATTACTATTTTTGCCAAAATACTCTCCTGATTTAAATGACTAAGAACATGATTTTAGTGCATTAAAAAGAGCTAGAATGTATTCACCTATCAATACATCTCTTGATAAAATTATTCGTAATTATTGCGCCAGATAGTGTCTCATTCTTATTTAAAAGAACTATATCTGAAGCATTAAACTTTCTAAACCATGAAATAATACTTAGTTTTTCCATTCGCTTTCTAAACTGCTGAGTTACATTTAATAATTATTTGTTTTCATGGCATAATTTTTTATGAAAAGATCATTTTTACTGCCAAGGCTATTTTAATTTCAAGGCTATTTTAATTTCTTTGAGCTCTTTTTTTTGATTAATAAAATCATCTAGTTCATCTATAATTTTCCTTTGTTTTCTTTTTCTTATACCTGTTATTTTTACTATTATATCTGTTGCAACCAATATGGGATTGCTATATTTTTATGGGACCAAAATGTCTTGCATAAAAGGTTAAAAAATAATGTTACAAATAATCAGGGGGATAAATCAAGAGGACTTAATCAGATTTCCCTTTCACTAAAAAAGGATATTCAAACCTTTATGATGATTTTTAATGCTAGGGGAGAAAAAATAATGCTTAACCTGGATGAAACTTCAATTATTAAGAATTAACACTCTACTAATAGCTTTTTTTAATAATTAGTATCCCAAAAGAATGTTGATTTTATAAATATTGTACGGGTTACCCTTACTGAAGAAAATGTAACAAATATTGGCGTTGCTGAATTATGGAATGAATCTGATTGAAACGGAAACATCCTGAAAATGTAGCTAGTGAATCAACAACCAAATATCATACCCCTGCATGTCCAGAGATTTAAAATAATATAATGTTTTTCGGTACAATCAGGCCAAGTAGTGTCGCAAACGCATATTTTCCCCTTCCACTCTAGTCCTGTAGGTCTTGATCAAGATTTGGTCTCGATCAGGAATAAACTGAGGGTAGACTTTATAGCGATCTTTGAGATAGAACAAGCAAGGCCATTGTCCAACTCTTGACCATAGGGAAGGGTCGGTTCAGTCACTATAGCCACCCAGCACCCAATCCAAAATTCCAGCCTTAAAATGGTTTATAGCCATCCAAACCCAGACTTTTTTTTTGAGCCTACAAAAGTTTGTAGTTCATCGAGTTCTCCTAGCTCTGGAACTGTGCCTTGTTCATAAGCATCAGGTAACTGATTACCCATCTGCAGTACTCAGCCAATCACAGTAGTGTGATATACCTTTGTGATTTCCTAAATCCCTCGAAAGCTCATGCCATTCACAGATATCTTCAGGCAAGTTCGACCAACTTCATCGCTTTAACTTTTGTGAAGCTTAGGGTTGCCTACAAACTGGCAAGAAAAACTGACACAGATATGATTTTTGTTTACCTGGTCTAATGCCATTTGGTATTCTGGACTTTATTGTATAGGAGAATCTTGAATCATTTACTCTTATATTTTGTGATTCATCCCCTATTTCAGTAACGCCGAATTATTTGTATAATATTTAATGCTAGTCTAAATAATTCAAATGTCGTTGCACAGTGACAAATGATTAGGAATATTGAGGAATGTGCTGATTTTTCAAATAATAGATAAGCAAAAAAATTGACTTGCATAACATGTCAATTGACTTGGAGTAGCATAAAGTTTTACTATGTAAGCTGGCTAAGTATTGTCAATTACGGTAGTTTTCTCCTTATACTCAGGTCATAGCTGTTTTACTGACCTTGCGCTCGCAATTCTCAATTAAGTAAGGATAAACGTTGTAGCCATAAGTAATATAAAGAAAACAAGCCCAATCTTGAATCATCTGCCACAATATTGTGAAAGTAACGGTCCAGCGATCGCCTATCACAAACTTAAGAATTCCTGACATTTGGCTATTTACGACCGTCCAAACCCAAAGTTGTTTTTTTTTGAGCGGATAAAAGTCTATAGTTCATCTATTTGAGTAGTTTCAGGATATCAAAGTTTTCTTCAAGAATCTGTGTCCCAGCAAGTCGTAACCAGTTAAGCACTGTCCAACAGAGAAATACCAGTCACTTTCTCAATAGCTCGGAATGCCATGCCGTTAAGGGACATTTTGACACACAGCTCTTTAATATCAGAACTGTAGCCCATAATGTTATGACTCCTGAGTAAAGCCTCCTGACTCAATAGTGGTCGCCTAAATTATCAGTAAAATATTAATTTTCACCTTAGCTATACTAGCCTACACTTCAATTAGGAAAGTATAGGCTTTGATTAAATATAGGGTCGCTATTGCTATTACCATTACTAGCGTAGACTTTCTCAGGCCTCTCAAACTTAGTCACAGCAACAATTTAATTGTTGACTTCTGACTTTAGTTATGGCTTTTCTAAGTAAATATACTTAAAATCCGACGAAAAAGTATATTTACTTAGCTAAAACTTAAGCAATTACCTTTTCTAAGTTTTCTTGAGTTAAGCTCATTAAAACAAATACTTTTTAATAGGACAATGGAGTATATTTACTTGGCCAAGACTTGAGTGATTACCTTCTCTAAGTTTTCTTGAGTTAAGCTCGTTAAAATAAATACTTCTTAATAGGACAATGGAGTATATTTACTTGGCCAAGACTTGAGTGATTAACTTTTCTAAGTCTTCTTGAGTTAAGCTCGTTAAAATAAATACTTCTTGAACTGTCTTTCCTTGTCTGGCAATAAGTTTAAAACCACCACGAATAGGCACTGATATTTTTAGCTTTATGTGGGGAATATGACTTTTGGATCTGCCGATAACCCCTGGAGTAACAGTTTCAATACCCTTATGTTGGGTTAATTTATCTAAAATTCGTATTAAGCCTTCAATATGGGTTGAATGATTCCAAACCAGACGACCTTTAGATTTAGATGATTTTCTCATCGGATTTTCTCCTTCTCTACATACCTAGTTTAATCTAGGGTTTGCTGAAAAAGCTGAAGAGTGAGGGCAGAAAATGGGCAATAGTTGCAGCAGATTAACTTTTTCCACTCAGATCAAGGAAAATCTAAAGTGGCCATATTAATTTATTAATTTTTTGTCGCTTTTCTCAAAGTAATATCAAGTCTGATTACGGGGCGATAACTACTTCAAAACCATTGTGGGATAAAAAAATCAGGATAAATGCATAGGAATAAAATCATTTTTTTTTGTTTTTAATAATAATAATTATTTATATGAAAAGGGGTACATTTCCTCAACATAGATAACCATTATGACTTCATTTAAATTCATTTTTATGTCAATTATTAATACTAGCTAATTGTTGGTTTTTATATGATTTGAATACTTACTTATTACTCAGTTTATTTTTATCTATTATATTTGTTGCTAATATAAATATCCTTACTTTCATTTTTTCCGTAACTATAACTTCTTCTTTTGTTTCTATTTCACTTTTTACTTGATATTTTATTTCAACTTAAAAAAATCATAATTATAAAATCTACTTTAATCTCTGCGGAATCTGGGTTAGGATTAAGATTTTTTTAATTAACTGAAATTAAATTTTCTGACGGCTATTTTGTTGAAAAATCAATCAATAAAATTTGATAGTGCGGGTGAGCAAAGCAACATTTTTGCTAAGAATAATTATCATTTTTAGGCGAACCGTAAGTTTATAAAAGAGTGAATCTTCTTTAAAACTTTTCTTTAAAACCTTATCTAGTAATAGTTTTGAGGTGCTTATAAACCCGTGTTCTTACGTACTTATTTTTAGTCCAAGAGACATAGAAATAAAGTGTTTTTTAGCTATCAAATAAAACAGGACTTCTTTGAAGATATTGTAGAAAAGTCCGACTTTAGAAGTTCGGTTGCACTGACTAGAGTAATTCCAAAATATCTTGTTAATATATAACTAATCTTAAATAGTTGTATTTATTGGAGGTAAATATTATGAATAATATTCCCGGCAGTCCTTCCAAAAATTTTTTCAGTCAATCAAATAGTAGTAATTTACTATGGCAATATGTTCAATCTATGAATCCAGAAACTGTTGCTCAACTTTCTAAGCCAGCTCCAGAAGTAGCTCAAATTATGGAACAAAATTTAAGAGGAATTTTGGGGAATTTGCCACCTGAAAATTTTTCTATGGCAATAACTACAAGTCGAGAAAACCTTGGTCAACTTCTAGCTTCTGCAATGATGAGCGGTTATTTTTTAAATCAAGCTAAACAAAGAATGGAACTTGAAAATCTGTCGATTCCTTTCACAAACGATAAAAATGAATAAGTATTCAACTTAAGATAATAATTATTCTGATTTTATGTTGTAATATTTTAGTATAAATAGATAAATAGATAATTAGTTTTTCTAGATTCAAAGCTTTGTTTTTTTTCTAGTTGACTAAGAACAATAGTATAAATATATAGAGTAGGGATAGGTTTAACTGTCAAAATAGAAATTATTATTCATCTATTATTACCTATCCCAGTAAATTTTTGTGAATTAATACTATTTTTTGATTATCACAACATTTCTAATGCTTACTTTAATTGTTTATAGAATTAAAATATTGCTGGAAAAATTGATTAACTTATCCCCAAATTCTTGGTTCGTTGGCATAACATTCCCTACAGTATGGTCACTATCAATATGTATTAACTCTACCCAAGGGGGTTTAGCTACAAATTATTAGCTATTTTGAATAGGAATTACATAATTATTTAAACCATGAAAAACTCAAACTTGCAAAGAACGTTAGATTTTTTTCCTGATAAATGCATAACCAAAATTATTTACCTATTTTAATTAAAACTTGTTTCTGGAAGTTTTATAGGTAAGACTAGAAGGTAGGTCGGCAAGATTAAATTGAGGGAATATGAGGTATAGATATAGTCATTTTCAATAAGAATGAGATACTATTTGGCACAATAATTACGAATAATTTCATTAAGAGATGTGTTTATAGGTGAATATATTCTAGCTTCTTTTAATGCACTAAAATCATGTTCTATCTGAATATTCCCCACTGATTTATGTCTCTCTTCAGGAAAAACAAGCTCGTAAGCTGACCCAAAATCTGTATAACAAACTGCACACGACCTTAAGACACCGTGGGTTAGAATTCCATAATCTATGCTGCCCCTTTTTCTCCTCTTTCCCCTAAGTAGAAACCCACAATTTCTTTAGTTTCTATATCAATCGCTAACCACAGCCATTGTTTATTATTTTTATTGCCTACAAATGAGCACATTTAATCACATTGAATAGTGATTTTACCGGTTTTTTTTAGTACATTTAATAGAGCGTGAAACCTCAGCATACTTATTATTGACGTAATTCTGGATCCATTTTTTGACACGCCTGTTACACAGATTATACCAGCAAAACTAATTTTTTCTCTATTTTAATTTATCAATCAGTTCTTGGGTTTAATTACTAATATAATCTATTTGACTATTTTCGACAAATTGTCTCTGACAATTTTGACATTGATATTTTTGTTTTTTATTGTGAATAGTCCCATTTTTGACAATATGATTACTGCCACAACTAGGACAGATTAATTTATGAATGGAAATCTGAAATATATAGATTTTTTCTTATTACTGTTATAGATAATAGCATACTTTTTTCATGATAGTTGAGCTTAATTCCTGATAGTTTGATGACTAATTATTATGTAGCGATAGCCCAGATAAAAATTTTAAATTATTAAGCCCAAAAAACTTAATCTTTTCAAGATTAATGTCAATAAATAATCATTTATATTGGCTTATCACTACATATACAGGACCACCCCTATTTTTACGCAAGTTTCTTAAACATTCTTTTTGTAAATTGTTATAACCATGTACGGACGTTGCATACAATATCCTGTTCTTTGTGCTCTATAATAATTATGAAAAGCCTTGTAAGTAGGGCTTGCTAATTACAAAGCATGTACTAATATTGGTGTTTAGCTTTTATGGATAGACAAAAGTGCCGATTTTCCGGTCTAAAAAGCTCAAAACAAACCTATACCTAGTTCAAAACGTAATATAAAAAATCATCTCACTTCTGACTTTTGATTTTTAAGTTATGCTCGAAATTAGGTAGTGTATTCAGCATTAATCTTTACATAATCATAACTAAGATCACATCCCCAAGCTTTACCACTACCAACACCGTCCCCAACTTTGACAGTGATTAATACAGTATCATCTAAGAGATATTTTCCAGCTGCCCTTTGCTTAAGATATTCCCTAGCAGCAGCTAGGTCAAAATCTAAGGGTTGCCCATTCTCCATTAGCAAAATATCTCCCAACTTTACCTGTAACTCCTTGTGATCAAATTTAACTCCGGCGCGACCCGCAGCGGCAGCTATCCTTCCCCAATTAGGGTCGCGACCAAAAATAGCTGATTTCACCAGAGAAGATCCAGCAATAGTTTTGGCAATTTTATTGGCAGATACTTCATTAGATGTTCCAGTAACTTGAACTTCTATCAGACAAGTTGCCCCCTCCCCATCCCGAGCTATCGCTTTGGCTAAATAAATACAAACCTCTGTTAACATTGCCTCCAACTTTTTTGCCTCTGCTCCCATATTAGTAATAGCAGATGTGCGAGACTGACCATTTGCCAGAGCAATAACTGTATCATTGGTACTGGTATCCCCATCAACAGTAATTTGATTGAAACTACGATTAACTGCTGTAGTTAACATGTCTTGCCATAATTGAGGAGAAACTGCTGCATCACAGGTAATAAATGACAGCATTGTTGCCATATTAGGATGGATCATACCAGAACCTTTAGCAATACCACCAATACGAACCACGCGATCGCCCATTAGAGTTTCTAGAGCTATTGACTTTGTAACTAAATCTGTCGTGACAATAGCTTTTGCTGCTGCTTCCCCTCCTTCTTGAGAAACTGTAGACACTAATTTGGGAATAGCTGCTTTGAGAGCATCCATTTTAATTCGTTGACCAATGACTCCAGTGGAAGCTAGTAAAATTAACTCTGGAGAAATATTTAGCGCTTTACCCAATTCTTTAGCACTTTCCACAGCATCCTGCCAACCTAAATCTCCTGTAGCAGCATTTGCTTGGCCAGCATTACACAAAATTGCTCTAGCACTTGGTTTATTCTCCAAACATTGGCGACAATAGTCCACACAAGCAGCTCTGACTTGAGTTGTTGTAAAGACTCCAGCAGCAATAGCATCTACGTTTGATAAAATCAAAGCCAAATCTTCTGCCCCAGAAGGTTTTAACCCCGCAGTTATTCCCGTTGCTTGATATCCTTTGGGAGCTGTTACTCCACCAGTTATTACTTGCCAGTCTGACATTTTTTTCCCTTTATTAGATAATTATGAATGGTGATTATACTAATTACTTAGGAGATACTTATTTAAACTTCATCATAAATCTAGATTTTTGGGATGGAGAAGCTTTGTTATTGGTATCTACACATTTTTAGGTTGACAAATCTCTGAAATTAAGTCTATAGAAGCAAATTCTATTAAACCCGGTAGTAATGGTTAAATTTTTAAGTGTTTTATATTTTGTTGTTCAAGCGATCGCTATATAGATTAACTTTTAAAAGTTAATACTATTGCCTAAGTCCTGATATTTGCGCTCCCAAGCTACTAATGATGCTACGATGTAATAAGGTGTTGGCGCCCTTACCACTATTATGAGTAACCCATTAGCTGATAAGTTTAGCCCTGCCTGCTTCTTGCCAATATTCTAAAGATACCTGTAATATGTAGACAACAAAGGCGACATAAGTTTTTTTCCCGTAATTCTCAATTTTTTGACAGCATCCCTTACATTCTGCTGGGTTACTTCTTCTCCCCACAACTTGGCTATCTGTTCTTGGGCTTTGTGCCCATTCTGCTCCATAAACTCTCGGATTTTTTCCAGGTCTTTAATTGTATGTTGCCCTCCTTTGATAAACCCGGGATTTTAACTTGTTATTCTCCCTCTTCTTTTCGGCACTTGAGCCAGGCACTACTAAGTATTTATACTCATACCGGACGACTTACTTCCCTCTGACTTTGTCTCTTGTCGACAGCCTCAAATAATTTTGGTTATAAATCATGGCTATAAGTTACTGGCCTGGGGTATCTATCGGCTTATCTACTCTGTATTATGTATCTACTTACTCTACCTTATAATGACTATCTCACCGAGCTAGCGCCATCTCCAGTCTAGAAATCAGGTGCATGCCTGGGTAAGTCCTAATTACTTTATTATTTTTGATTTTTAACTTTTGATATAAGAAAGTTACCTGTAAACCCGATAGTTGACTTGAGGAAATATATTATCGATCGCCTCAACCTTTTCCAACCAACCAGAGTCAATCTTTCCCTGTAGAATATCTTCATAGAGCTTGTTAAAACGCATCAAATGTGATCGTGTCCTCCGCACAGCATAAGAAACCATAGTACCCGTACTCATAATAAATGCCCAGTCTGAAGATTGAGCCAGCAATAATTCTCGGCCTGCCTGATTTAAAGCCTTTAATACCAATTCATCTTGTGCTTCGTATTGTGCCAATTCAATCATCCGTTCTGTGGCCTTATGCAAATGAGGATAAATCCAAGAATTAGTATGATTAAGCCAATATTCATGAAAACCCTTATATCCCCAACTAGACTGGGCTGGAAGACAAACTTGATGTTCAGGATGTTTCTGTAAATAATCTGCCAAATGAGTCATCCGATAAGTGCTTTGGTCATACCAAGTTTTGCGGAATAAGAAATCCAAAAACCAAGGCCCTTCATACCACCAGTGACCAAACAACTCAGCATCGTAGGGAGAAACAATTATCGGGAGTTGCTCCATAATTTGATATAAGTGCTCAACCTGACGCTCCCTATTAAACATAAAATTACCAGCGTGTTCTGCTGCTTTTTCTCTGGCCCAGTATGGGTCGTAAAGTTGTTTATCTCCTAATCCCAGACCACGACCTGTAATTTTATGGTACTTAATGCCAGTATTCTTGCGCTGGCCATCAGGCATAATATAAGGCTTAATATATTCATATTCTGCTTCCCAACCCAAATCCTTATAAAATTCTCTATATTCTGAGTCTCCTGGATATCCTACTTGGGAAGACCATACTTGTTGAGAAGATTCATGGTCTCTAGAAAAAACGGCAACTCCTGTTTCTGTAAAAATAGGAGCATAACTCCCATATCTGGGGCGAGGTCTAGCGTAGAGTACACCATGGCTATCTGTTAAGAAATAACGTATACCAGCATCTGCCAGTAATCGCTCTAGACCTTGATAATAAGCACATTCTGGCACCCAAATACCTGTGGGGCGACGACCAAAGTTTTCTTCATAATGTTGACAAGCAACTTCTATTTGGGCCCATACTGCCTGTGGATACATTTTCATTAATGGAAAGTAGCCATGGGTAGCTCCACAGGTCATAATTTCTAGGTTGTTGCTGTCTTGAAACTGCTTAAATGCAGTAATTAAGTCACCGTCATAACGTTCCCAAAGTTTCCGAACATTATTGAAATGGGTAACGTAATGTTCTGCCAGGTAGCGAAGATGACCATTGTGGATATTGTGGTCAATTTCTTTATCTGCTAATTCTTGGAGTAAGGTTAAGTGATGTTCATAGCGGCCTTGTAGCAGGGGGTCTCGTAGCATGGACACCAAGGTTGGTGTCAAACTCATGGTTAATTTAAAATTTATACCATCTCGCTTTAACCCCTCAAACATTTGGATTAGGGGGACATAAGTTTCTGTAATTGCTTCAAATAGCCACTCTTCTTCTAAAACATAATCCCTTTCTGGATGTCGCACAAAAGGGAGATGGGCATGAAGCACAAAGGAAAGATAGCCAATAGCCATAGTATCTTAATAATTAATGAACTAAAATCTAAATTGAAAAGAATTATAATATTTCCTTCGATTTTATTTAAGATTTTGACATCCTCCCCGGCCTGAAAGGACAGGGACTCCTACTGAGCCGAAGCTCCTCGGTGGATTGCCCAACTGCGACAATAATACTATAGGTTGTGTCTTCTTGCTTAATTAATTAAAGGGTCTAGACAATAATATGAATGTGGGTAAAGTTAGGATACCATGCTAACTTTTGTAAAGTAATATGATGGCTATAGATTAACCAAACTGAATATCAGCGACTGATTTCCTGAGGCCAGTATATTGAAGAAAACTTCAATTATTGATGACAAATGACTTTATTTTAGTGCCGCTAGTTCATTTATCCTTTTTGGACACATCACAGAATAATAGAATATAATTGTAGGCAATTTCTTGCTGATCTGAAGTTTTTTTTATGGCTGGCCCTACGTTTATACGGTCTGTTTAAATTCTTCTGGCTTTCACCTTTAAATGCCTGTAGATCAGTAAGTACGGATGTTCTTAGCTGAAGTGGGAAGTAAACATGAAAATTTTACTTCTTATGACGTTTTATGTCGGTTTTATGAAGCAGAATATAAGGCTAAGACTTATATACTTAACCAAAAGTGAGCTGTTGGTCAGCTCAATAACTTCTGAACTGAGTGAATTAAGATGATGATCAAAATTGAAATTCAAGGCCAAGATGCTGTCCTAGCTACTGAGGAAATGCTAGCAATTAATGGACTCCAAGGTAGCTATTAAACAATTAACGAGGTTGAGAGAGAAGGAGTATTGACAACTATTGCCACAATAGTTGGTCTTGTTGGCGGTAGTTTAACCATTGCAGAACAGCTTTACGAGTGGAAAAACAAATATCAAAAATCTCTTCACACTTCGGCCCAACCTCGTATAGAGAAAGTTTTGGTTGTTGCTCCCAATAGTGGAAAACGACTGTTACTTAAAGATGCAACTATAGAGGACATCAAAAAGATTATTGAAGATTAACTAAGGCAATAGTACAGTTATGCAAATTCTACACCTGAATCTTAAGCTAAAAGGAGATGATTCTGTTGAATTCCGTTTCTATTGGGATAACCTCCTCGAGTTTCAACCTGTTTCGCGCAGTCTAGGAGAAATCTCAGACTTAATTAAAAAGTCAGAAGCTGAGTATTATACTTACCTTCCAGTAGACTATACCCAAACAGGTCAAAATCTCTACAAATGGCTAAATGGAGATAAACGGGATCTAGACAGAGTAATTCATGATGGTTCATCAGGCGAAGGAATTGTTCTAGCAATTGCAACATTCGAAGGGCTATCACATCTACCTTGGGAACTGCTGCATAATGATGAAGATTTCTTAGTTAATTCTACACCTGCAATTGTTCCCGTTCGTTGGGTGCCTAATTCAGGAAGCATGAAAGTACTTACTATGGATGATAAACCCAAGAATGAAGCATTGAGTGTGGCATTTATGCCAGCTTCTCCTCACAATAAACCAAAATTAGACCTTGTAGAAGAGGAAATAAGTATTTTAAAAGCAAGCCAAGAGTCCCCTTTCTCTCTAGAAATAGAATATAGTGGTTGCTTGAATAAGCTGAAGGGTTTGATAAATAAACATGATAAAGGCTTTTTTGATGTGCTTCATCTAGCAGGTCATGCAGAAAACTCTTATTTGATTACAGAAACAGAATCTGGAGAGGCTAAATATAGTAGTGCTGAAGATATTGCTGATGCACTACTATTTAAAAATCCTCAACTGATTTTCTTGTCGGCTTGTCGGACTGCTTATTCACGGGAGTCATCTATTCCTTCGATGGCTGAAAGTTTAGTAAAAAATGGTTTTAAAGCAGTTTTGGGCTGGGGCGATCGGGTATTAGATACTAGCGCAATAGCGGCTGCAGAAATATTTTATCAGAATTTGTCATCAGGTTCTACAGTAACCCAAGCTTTGGCTCAAACTTATCGGAAACTAATTGAAACAGAGAAAGGTTGGCACTTGTTGCGATTATATGTCAAAGAAAGTTTACCGGGAGCATTAGTAACAGCATCGGCAACACTTGGACGAATACCACCGCATCGGAAAATAACGACTCTACCTGTAAAAAATTGTTACTATCAGCTGAAACAATGTGTATCTATCCTAAAACAAGATAGTAAAAAAGGTGTCTTGATTTTAGGAAAAAGTAATATTACTTCCTTATTTACTGATGGACTATGTGAACGTTTACCCAAGTCTAAGATTGTTAAATTGGATCAACAAATTGATGAATACGAATTCGTTAATAAACTAGCGAGTGAATTGGAAAATTCAGAGCAGCGTAATGCACTTCGTAATGCATTTCAACGCGGTGATAAACTTAAATATCCACTAAGAGATTTATTTAAAAAACGGAATGAAACTGGACTAGAACCTTTAGACATCTCCAAAAATACTCAAACATTTATCCTAACTATCTTTAGTGGTGCGATCGCTACTTATGAAGATAGTTAATTTGTACAGTTTTATGGGCATCAGAGATACTTCGTGTTACTAATTAAAATATTTATTGTACTTTGATTTATTATTTTTATCTCGGCTTTTGATGGTTTATACTAATATAAAAGAGCCAATTCTTAGTCGCACTAAATCATATATTATTAAGATTACTTTTTGATAATTATTATCTTTTAATCTGAATCTTTCTCTAGCAATTCTAAATATTTTAATTAATCTTATTATATGTTCTAAAAATATTCTCTTTCTGGCTTTTTCTTGATTTTCTTCTTTGATTTCTAGCGGCATTTCTTTTTTTCTTGGTTTCTTTTTTGGTGTAGTAGTTCTTTCTACTCCTTCATCAGCTTTATCTCCTTGAAACTTTTGTTTTTTATCAAATTTATCCTGTTGTTTTCTTAATATTTTTACATCACTTACTGGACCTTTTTCTCCTACTATTACATCTACTATTTCTGTTCCTTTTGGTGTCGTTATTATTTGATTTTTAAAAGTATAATTTTTCTTTTTTCATATTTGATATTTTTCTTGGTCTTTATATTCACTTGGTCTTTCTATACTTTGTTCTGTACTATCTACAATTAATTATAATTCTGTTAATATCTCCTTTACCCATTCCAATTCATTTTCTTTTTTTTTACTTGTTCTAATAAACTTGCTGGCAGTAATTCTCTGAGAATATCTATCCAGTAATGAAAAATATTATTAGCACTTGATTCACTTATACCAAAGTTAATTCCTAATGTTTGAAAAGTTGGTATTTGATGTAAATAAAATAACGTTAAAATTATTTCTTCTTCCTTTGTTAAATTCTTTTTTCTGACTCCACCTGCTTTAATTAATCTTTTTTCTGTTTTGGCGATCGCCTCCTTTTTCTCTGATTCTATTACTTGGGCCTTTGCTATTAATTTTATTAGCTGTTCATAAGTAATGCCAATAATTCTTTTTGTTTCTTTTGGATGATTATAAATATATTCTAAAGTTGGATTCATTTGGGAGACTTTATACATAAATGGTTTTGATAATTTTACCTTATTTTCTATTTTGGAGATGTTTAATGAAGAAAATCTCCAACCCTAACACCCAAAGTGAAGCATTAAGCCATTTAGGAGTTACCATAAAAAATCATCAGTTAAAGATTGAATTTTCTGAAACTGGGAACCCTTATGCAGAGCCAGATGGCGATCGCACAAAAGTCTCTGATACTTCAACCCAAACTGTTACGGTAGAGCTAATACTTGATACTCCTCCTCCATCTACTCTTAAACTTCAAACTGAAGTTTCTCCATTTACACAAGGGTGGTCCTGTATATGTAGTGATAAGCCAATATAAATGATTAGTTATTGACATCAATCTTGAAAACATTAAGTTTTTTATGCTTAATAATTCAAAATTTTTATCTAGGCGATCGCTACATAATAATCAGTCATTAAACTATCAAGAATTAAACTCAACTATCATGAAAAAAGTATGCTATTATCTATGACAGTAATAAGAAAAAATCTATATAATTCAGATGTCCATTCATAAATTAATCTGTCCTAGTTGTGGCAGTAATCATATTGTCAAAAATGGGACTATTCACAACAAAAAACAAAAATATCAATGTCAAAATTGTCAGAGACAATTTGTCGAAAATAGTCAAAGAGATTATATTAGTAATGAAACCAAAGAACTTATTGATAAATTAAAATAGAGAAAAAATTAGTTTAGCTGGTATAACCCGTGTAACAGGCGTGTCAGAAAAATGGCTCCAGAATTACGTCAATAATAAGTATGCTGAGGTTTCACGCTCTATTAAATGTACTAATACCAATTTCCTAAAGTCCGACTACACATAATGCTTCAAGAATAAAATCATATCCTGTACAAGAAGCAATATCTTTTTGACTAAATCCAGTTAATATATTTCTCAGGATTCTGCGTCAGAAATCTAAGGAATCGAAAACTCGATTTTTCAAGAATTTTTTCACCTCTTTCCACAGTCTTTCAATGGGATTAACTTCGGGACAATAAGGAGGTTGAAATAATAAAATGATGTGATCAGGGATAGATAAATCATTCCCTAGATGCCCTCGCCCGTTATCTAGTTGAATAATATGAATCTCTTCAGGATATGTTTGAGAAAAAAGCTCTAAAAATCTTTCAAAGCAAGGAGTATCTAGATGACTAAATTCATAAAAAAAGGAATCTCCTGTTTTTGGTTCTACTAAACCATAAAGCCATAGATATTTAAATAGCCATTGATATAAACCAATGGGCTTAACACCGCAAGCAGTAATGACTTTACCTGTTATAGTTTTTAATCCAATTCTAGTCTCGTCTTGACACCAATAGCGAATTGGCAGTTGATTTTCCGAATATTTATTAATTAACTTAATTTTCTCTTCTAGTTGAGATGAGAGTTTTTTTTAAAGTTTTCTTGAGCTTCTTTATTTTGTTTTATGTGATTTGGACGTGGAACTTTTAATTTACTTTTTAATTTATATCTGACTAATTGATGAACTGTTCGATAAGACAGCTCGATGTCAAAACAAGTCGTTAACCACTGTTGAATTTCACCATAGCTTTGGAAACCTTCCGGGTTTTGCAATTCTGCTTCTAATTTCTCGATTACATTTGGTGGAATTGAACTTGGCCTCCCTCCTAGATTTTTCTTTGGTTCTAGTAAAAGATTCAGTCCACCTGTACGATATTTCCCTAACCATTTTTGTACTGTGACTCGATTGCGTCCTAACATTATCGCAATTTCTTTTACTGTTTCTACTGTTTGAGTTTTCAACCAGTAAATAGTTTGAAGTCTTTCCTTTTCTTGAGCTGTACTCGCACTTTTTAAAAGTTTTTTGAGAGTTTCTACCGATTCATTTATCTCAATTTTTACTACTCCTGACATGGGGACATTTTCTATAATAGGTTACTTCTAAAAGTGTAGCTTAAGTTTATGAAATTAGTATAACTAAGATGACAGCTGAAGAGCTAGCAATAGATCAAGAAACTGAATAATTTAGGGTTTGCTGAAAAGGTCTTTTTAAAGAATAGGTAGGTAAGTTGTATGCAACGCCCCTACGGAGGAAAAAAAAATTTACCCACCCCTAATCTCGACGATGGAAGGATAGATGGAAGAATTGTCCCTTAATTTTTCTGCAGTGGTCAGCCCAAAATCCTAACTTTTTGAGCTCTCAGAATCGAAAAATAGACACTTTTTTCAAGTCGCAAAATGCTGAAGCCTTTATGTGTCAATGCTTTAATCTTTAATCAGAAAACCATAATTTAGCTGTAGTGATAAGTGAGTAAATCAACACAGAACTTACGCGATCAACCGTAGAAACCAAGCTTTTTCCTAGATGTCTATTGTTAAAAACAACAATTTATTTAAAAAACCGGGTTTATTTGCGCAAGTCCTAAAACATATCGGTACAAGTTTTTATTGAATGGAGAAAAAAACTTATGGTTACTCAAGCAGATCCAAACCTAAATATTTCTAAGACTGGATTAGAAGCAAATTTTTTTATTCTAGAAAAACGATCTTTCAAGAATAGACCTGATTTACTTCCAGAAAGTTCAGAAAATAATTTACCTAATGAAAAGCCTTTTGAGACTCTTTATGACGCATTTGAGAGATATAAGCGTTTAGTACTTTTGGGAGAACCGGGAGCTGGAAAAACAGTAGCTTTACAAGAATTTAAGAAAAATATATCTAAGAAAGAGAGACAGGCAGAAAATAATAGCCTGGTTATATTTGTATCCATTCAAAAATGGAAGTACCCAGCAGATATTGTTACGTTTTTAGCTAAAGAGATTGGTAAAATAGAGGAGGATTTCCGGAAAGAAATACAAACAAAAAGACTTTTATTACTTTTGGATGGATTAGATGAGTTACCTTCTAATGTGTCAAAAAGGTCAGAAAGCAGAGATGCAGAAATCATAGACTATCGCGTTCATTTTCTCTCGAAGTTATCAGATTTTTTAAGAAATTTAAATCCCAATAATATTTCAATTGTGATGACTTGTCGTAACGGGACTTTAGTGAAAAAATAGTAAAAAAAAGGGTATAATGTATACCTGATATGTATTTTACGTTAATTACTGGCCTGGGAAAAGTTTGATGAAAGAAACAACTTCAGTGGCCATGCCCTCTTGTTTCCATCGATGGTGCGATCGCTTTAACAATGTCTTTAAAACAAAAGCCCAAAAAACAGGGTTTAGGGAATATATAGGAGGATTACTCTTGAGAAAGCGATCGAAAAAACTTGTCTCAAATTGCCAACAACACTGTAGGTCACACGTACCACAAATTACGGCATTTTCTAGTTCGAGCAAATTGGTCTGTAGATGCTGTGAATGAGCGTCGTCTTCAAGTAATGTGGGAACGTCGCCAAACAAAACCTTCTCGATCCTATTGCTTTAATTATAGACGATTCAGGCCACAGAAAAAGTGGTAATTTTACTGCAGGAGTAGGGCGGCAATATATAGGAGAAATAGGAAAAACAGATAATGGTGTAGTCGTGGTGACAACTCATCTTTATGATGGAGTTAAAAGTCTACCTTTAGACATAGCTTTGTATCAGAAAGCTGATTCTTTTCCAAAAGGAAAAAAAGACCCAGAATTTGTCAAGAAACCAGACGAGTGCAATGTCTCTAGTAGATCAATGTTTGTCCAGAGGACACCAACCAGAAATTGTGTTAATTGAAATTTGGCTATGGTAACAATACATCATTCTTAAATCAACTAGAGAAAAGAAGTTTAACTTATATAGGAGGATTAGCTAAAAATCGAAAAGTCATCATTAAAAAACAAGATGACATTAAAGAGGAAATTAGATTAGACAAGCTGGCAGAAAGTATACCTCAGAAAGCTTTCAACTTAGTTCAACTAAGTACAAAAAATGCTAGAGAAGTTTGGGTAGCTACATTAGAAGTAGAAATATCTAGGATGTCAGGTCAAAAAACTATAGCTATCGTTATGAATGCTAAAAGTTTTTCTGAGGCCACTGATATTAACTATTATATCACTAATAGAGAAGACAAATATGTAACTCCTGAGTGGATATATTCTACTTATTCTCAAAGAAATTGGGTGGAAGTTTTCTACAGGGAAGCCAAAGGATGGTTAGGATTAAGAGAATATCAAGTCAGAGATAAAATCAGCCTTAAAAGGCATTTTATTTTAGTATTTTGTGCTTATACATTTATTATCTGGCATCAGTTAACAGGAGGTATAAGAAGGCGTTGGGCTAACAAACCATTAAATACGTTTACTGATACTTTAGAAGCATTTCGTACCGCAATATCTTATCGTTTTGTTGAGTGGTTAGATGAAAACATCGACGTATTTACCGCTCATAAAGAGAGTTTAGGGTTTGTTTGGGCTTGAAATTTGCTAAAGTCCCGGTAATAGAGATTATGAAGAAATACGGCGCAAAATTCAGGAAGAAAAAAAGGATTTTAAGAATATTTTTCATGGGTTAGTTGTTCTCAACCGTTTAAAAAATGATGAAATTAAAACATACTTGAAAGAGATTAATCAAAAAAAGCTGAATAATTCTTTAAATGGTGAAAAAATTGATTTTGATTTACTATGGAATACTATTCAAGTAAAGAAAGATTTGTTGGAATTAATTCGGACTCCATTTTTGCTGTATGTTCTATCATCCACTTTAGTGTCAATTTATCAACAAAATCCGAGTTCTATTTCTCAAGGGATAGAGGCTATTTATAAAGCAGTCAGTAATTTAGAAAAATTACTCGATAAATTTGTTAGAGAACAGTACAAAAGAGAGTCTGGAAAGTCCAAAATACCGATACCATGGTCACTTAATAAAGTCAAGAGATTATTAGGTCAAATTGCTGTATTAATGATGAGCGATCGCGAGCCAGATGATAATGAAATTTTGCCAGAACACTTCAATAAAGTAATTCAAATTCAAGAAGACATTAAAAAATTTATTGATTTGACTAAAAATCTATATTTATTAGAATCTGAAGAAAAAGCTAATAATCAGAACCCAACTTCAACCTATAAGTTTCGGCATTTAACACTACGTGATTATTTTGCTTTCGACTATGGTTCTAATTTTTTTGATCAACAAGAGGATAACTTCAACCAAAAATCTGAAAAATTTAAATTAGAAATAGAACCAGAACAAGTCGTAAAAGCGATTGGAAAAATCGAAAAAGAGCAAGTAGTTAAACTATTAACTAAGTTACTCGATCATCCTGATCCAGATGTACGTTACGAAGCTATAAAGTCTTTAGGGGAATTGAGAACGCTAGTATATGTTGAAGGCTATAACAGCGATTTGAAAAATCAAGTTGTCAACTACTCTCTTGATGAATTTGATAAATCCCTAATTAAAGAATATTTTAGCGAAAAGAAATATTTTGAAATCAATGATAATGAAGCCAAAAAAATATATCAGTACAGTGGTGGAAATGTTTGGATAATAGAGCAAATAGCTACCATGTTTGGTGTAGTTTCTTTAGATGAAATATTAGGTGTTGATGATGTTCCCATGCCTATCGCAGCTAAGAGTCCTGATGAACAAATTTTGGCAACAACTGTTCAACGTTTGTTACATTACTGTGTAAACAAGGAAGATAAACGCGCGGTTTACTTACTTGCCATAGCATATTGTCCAAATCCTGAATTTCTGAAATTCATGTTAGGTTGTGAAAACCTAGATGCTAAATTACAGGAATTACACAATAATTACCCATTTATCTTGCCAGAAAAACAACAGCTAGAGGAGATACATCAGAAGTTTACGAAACAATACTTACTGTCACTGAGAAATGAAAATAATTTCAACAAGTATGAAAGTGAATCTCAAAAAATAGCTAAAAATCTTAATCGTAAGGCAGCACATTATTTTCAGGATAAGATAGAAGACTTAACTGGAAAACTAACAACAGCAAAACAGCGTTTTCGGAACGAAGAGTTTCCTGATTTTATAATTAATTGGTTTTATCATAGATTCTGGCTAAGTAGTAAAGATAATGTGGAGTATATATGGAATGATATGATTCCCTATTTAGTAGAAGGGTGGCGTTATAATAATAATTTTGTGATTGAACTTTTAAAAATTGCTGGTGAGTTTGATAAAGACTATGAATTTTTCCAACTTTTCAAAGCTGTTTTCATGGAAAGAAAAGATCCGTATTCTCTTGTGAAAAAATTGGTAGAGAAATCAGATAAGACTACAAAAAAAGACGAATGGGTAGCGATCGTACTGCTTATATATTGTGATTTTCTATACGAAGAAAAGAAGTATTCAGAAGTTTTAAAAAGATGGGAACAAGCTCAAATATTTATACCTGAAGAAGCAGAAGATCTAAGAAGGTCATTTGAAAAATTACGGAGTCTATCATTTAAGCAAGAGAAGAAAAATGATTTTAAAGAAGATCAAATAGAAACAGAATCTAGTCCACCAATAGACCTCTCCAAAAATATAGATTTGGGAAAGGTGAGCTCTGATATATTATCTAGATTAGAGAAGTTAGAGAATCAGCGTAATACATTTTCTCAACAAGCAACTCAAAAGGAAGAAAAAACAGAGTTGCAGCTAAAGCAAAATTATCATCCAAATGAAGAAAAAATAGAAGAAGATAAAGAACAAAAATTTAACTCGCAGACATGGTCAGAAAAACAAGCAAATATTCCTAAGAAAGAAAAAACAGAGTCGCAGCTAAAGCAAAATTATCATCCAAATGAAGAAAAAATAGAAGAAGATAAAGAACAAAAATTTAACTCGCAGACATGGTCAGAAAAACAAGCAAATATTCTTAAGTCTGATAATGAAAAACTAATATATCAATTAAAATTTTGGCATTTGATAGTGCTAATATTCCCGTTATATATTATTATTTTAGTATTTTTCTTTTTAGTATATTTAATATATGAACAGAATAATATGCCGGAGAAAATTCAGATTAGAAATGAACAGAATAATATGCCGGAGAAAATTCAGGCTAGAAATGAACAGAATAATATGCCGGAGAAAATTCAGCCTAAAAATGAACAGGAATATAAAAAATTAAATGAACAAGAAAATGAAAATTTGATTGAGTCAGCTATTTTTTTTGCTAAGAATAATAGAGTTGATAAAGGATTGGAAAATCTATGCGAAATACCTAGAAATTCTAATTCATTTAGGGAGGCTAAACAGTGGATAAATAGATGGTCAAAAGATGATTACTGGGGTCCGCAATTACCTTCAATTATTGAAAAATTTCAAGAAGAAGGATTATCATGTCCTGCTGCAGAAGACGCAGACCTAAGAAGGTATTAACTTAATCGGATAAAAACGATTTAATATGAAAAAAAAGCATTCTATTAGTCATAGATAAAATTCATGTCTTTGACACACCAATGACTAAAGTTGCGTAAATTATTAAGGGTCATAAATTTAACCGAATAAAGTTATATTAAATAGTAAATAACAGAATAGATATAGGCAAGATAATCACGATAAACAGAAAAAATATTACTCTGGAAAAAAACAAAAATTATACATTTACTAACAATGATTATTTGTAAGGATATACAGTACCATCGGGTAAAATTGCACCTTTTAGTTGAGCATCAATAAAGCTGGCATTATTTATATTAGTATCCCGCAAATCTGCGTCTCTTAAATCAGCATTCCAAAAAATAGTTTCTGTTAAATCAGCTCCGCGTAAATTTGCCTTCTGGAGATTTGCTCCCCAAAAGTTTGTTCTCTTGAGGATAGATCTCTGTAAGTTAGCTTCTTGTAAGTTGGCACTGTCGAATTCTGCTTCTGTTAAATCTGTATTGGTAAAATTGGCTTTTTCAAGATTTGTATTAGAGAAGTCAGCATTCTGTAATACTGAACCAGTTACATTCATTTTTTTATAATTAGAATTACTGAGGTTAATCTTGGAAAGATCACAATAAAAACATTCTCTTGAGCGTTTTAAAGTTTGTGCTTGCCACTTTATGTATGCAACTACAGGTTTGGCAAAAGCTAGTGAAACTAATAGATTTATTATTAATATTTTGAGTTTGATTTTAGCCATGACAGCATTTTTTGAGTTAATAGAAAAAAATGAGATCAATAGAGAAGTATTATGGCTGAGGTTAGGAATTAGGAATAGAGAGGTAAGTTGTATGCAACGTCTGTACATAGAAAAGGGAATTAAATTAGGGTGTAATTGGAAGAATTACCGTTCTGTTAAACTTACTCAAAGCAAAAGAAGCAGGAAGTACATAAGCTTTAGAGAAGTATTATGGCTGAGGTTAGGAATTAGGAATAGAGAGGTAAGTTGTATGCAACGTCTGTACATAGAAAAGGGAATTAAATTAGGGTGTAATTGGAAGAATTACCGTTCTGCTAAACTTACTCAAACCAAAAGAAGCAGGAAGTACATAAGCTTTGGAGCTAGCTTCGGTGTTTCACACTTATACCACTGACTGTAGTCTATAACTTATCTTTGCTCTTCAGGCAACAAAATAGCCAGGAAGCTAAAGCTAGTTATTTACATTGTTTCGCGTTATCGTGAGCAGCATCAAACCCTTTTTCAAATGAAAGGAAAAATCTCTATAAATAGCTACAATTAAAATTTTTGTAGGAATTTTCAATTGAAAATTCCTACAATTGGTTCTATAATTTTAGGTATTTGTCATCCAAAAAACTTTAGAATCTCAAAGGAGAAAAGCGCCATACTTTAATTGTGTCATCAAAACTGCCACTAATTAATGTTTTTCCTCTAGGATCAAAGGTTAAATTTACCCAAGCAGAATGTCCTTTAAGGGTTCCCATCAAACCACCTGTCTTAATTTGCCAGAGTTTGATTGTACCGTCAAAATCTCCACTAGCTAAGGTTTCACCGTCTGGACTAAACTGGAGAGATTGTACTTTCTCAGAATGACCAATTAAAGTACGTTGAGAACGTCTAATTACTCTTTGAAAACTATTATTATTAATCTCCCAAAGTTTAATCGTCTTATCCCAACTACCACTAGCCAAAGTCTTACCATCGGGGCTAATAGCAACCGACCACACAGGTTTTCGGTGTCCCTTCAGTGTGCTGAGTAGTCTACCATCACGCCAATTCCATAGTTTAACAGTACCATCATTGCTACCACTAGCTAAGGTTTTGCCATCTGAACTAAAAGCAACAGACTGAACTACATCTAAATGTCCATAAAGAGTATATAACAACAAACCACTATTAATATCCCACAGTTTAATAGTTTTGTCTTTACTGACACTGGCGATCGTATTGCCGTCTGGACTAATGGCTACAGACAAAACATCTTGAAGATGACCAGATAAGGTATTTTTCAATCTACGAGTGTAAAGATTCCAAATTTTGAGCGTACTATCACCACTAGCACTAACGAGAGTACGACCATCTGGACTAATAGCAACAGACCAGATGGGTCCATCATGTCCTGATAATTGACCCAAATTTTGCCCGCTACGCAAATGCAATAGTTGAATACTCCCGTTTGTACTACCACTAGCAACAATACGACCATCGGGGCTAGTGGTGATCGACCATACTGGACCGGAAGTTGTTGCTAAAGTTCGTAGTGGAGAAAGTTTGTCTCCTACTCCTGTATATGGTTGTAATGATGGGAGTGTGTTTTTATACTCCTCCTTAATTTTTGGTCTGGGGAAACTTCGCTCTTCATTAGGAATAGTAGTAGTGTTGGAAGATGGAGAAAGTGATGGCCGAGGTTTGGCAGATGGTACACGAGAGCTAATTACTAATGATAACATAGCGATCGCTACTCCCCCCCAAATAGTTACATTCCAATTTTGTTTTTGCAGTATAACATCTGCTGGTGTTGGTCCATACTTGATATCTTTAATAACTTCTGCTGCAGACTGATATCTTTGACGATGATCTCGTTGTATCATTTTATCTAAGATACGACCAAGATGTCTACTTATGGGATGTTTCAAATAGTCTTGCCACACCCACTTTTCGGCTTTAATATCAAACAGTTCAAAGGGTGAAACCATTGTTAATAGATGCAGACAAGTTACACCTAAACTATATATATCACTGTTGGGGTAGACTTTCCCCTGTGTTTGTTCTGGGGCTGCATATTCAGCAGAACCATTAATACTTCCTATTGAGAATAAATCTCCAGTAGCGGAGATAGTTACTCCAAAATCAACTAAAACAAATTCCTGAGTATTTGTTCCTTGCTTTCTCCGACAAATTATATTTTCTGGTTTAATATCTCCATGAATCAAGTGATGGTCGTGGATCAACTCCAAAACTAGTAATAATTGATTCAATATTTGCCAAATTTTACTTTCACTAAAGACACCATATTCTATAAGTTCTGTGGCCAGATTTGAGCCTTCAATGTATTCTTGTACTAAATAATGGTGGCCATCATGTTCTATAGATGCTAATAGTTCCGGAATATGGGGATGTTTGCCAATTTTGTCTAGCTGCACTGGGTCACAGCTAAAAAATGTTGGAATAACTTCTTGACTCTGAAAAACTAGGTCCTTTATGTCGTCTAGGTTGACAAATTCTTTGATAATACACGGTGGTTTAGAAGGTTTATCGTGGTCAATAGCGAGAAATGTATGGTTCCAGACACTTTCACCCAAGGGTTTGATCACTTGGTAGCGTTCTTTGAGTATAGGTGGACATTTGGATGTTCCCACTATTGTCTCATTTTGACTGACAATATTCTTGTCAGCATCTTCTGGATTCTGGTTTTGAGAATTGATGCGATAATTCATGATCAGCAATCAATAAGCATATTTGTTCTATGATAATATTTATCAGATTTTATCTACAAACATCATGGAATAATTGGTGGTTGTATGAATTTATGGTTGTTAAAATGACAAAGAAAAATTTGTAGCAGTAATCCGATAAAATGGTTGTGACAATTCAAAAACTAAAAATAAACTCCAAAACTCCTATCCTTCTACCCACACTTATCCAAATCCCCATTCCCAAAAGTTGCCAAGTTTTGGACAACATAAAAATAGGATTGCTATAGTATCAATACCCTTAATAATATATATTATTAACTAGCTGCAAAAGTAATAATTTTTTTGTATTCTAGTTTAAACTCATAGTCACTAAAAATTAATTATGCCCCTAATCCATATCAAAAAATCTTGGGAAATTCCTGAAAGAGAAATTACACCAGAAAAAGTTTATGTAAACCGCCGTCGGTTTATGAAAAACCTGATAGGTACTGGTATAAGTTTTACTGCTTTATCTACTCTTACAAGCTGTGCTGAAAACTCAAAAAAATCTCCAACTTATGAAGCAGTAAATTTACCAAAAATTAGCAATTTTACACCTAATTATAACTTCGCTAAACTTGAAAGTTCAATAACTGATGAAGCTTTAGGAACAAAATATAATAATTTCTATGAATTTGGCGGTACTAAATCTATTTGGAAAAATGCTCAAGCTTTACCAACTGAAAATTGGCAAGTTGAAGTTACAGGTTTAGTCAAGAATTCTCGTATTTATGACATAGATGAACTACAAAAAAGGTTTCCTCTCGAAGAAAGAATATATAGATTTCGGTGTGTCGAAGCTTGGGCAATGGTAATACCTTGGCTTGGCTTTCCTATGAAGTTATTAATGGCTGATGTAGAACCAACATCAAAGGCTAAATATGTTCGTTTTACATCTTTTTATGACCCACAAATTACTAAAGGTCCGGGTTTTTGGGCAAGTGATTATCCTTGGCCTTATACGGAAGGTTTAAGAATAGATGAAATGGCTAACGAATTAGCTTTTTTTGCTATGGGAATGTATGGTAAGTTATTACCGAAACAAAATGGAGCACCTCTAAGAGAAGTTATTCCTTGGAAGTATGGTTTTAAAGGGGCAAAATCTATTGTAAAAATTGAATTTTTAGAACAAAGACCTGCAACATTTTGGAATACTCTGATACCAAATGAATATGGTTTTGAAGCAAATGTTAATCCTGAGGTTCCTCACCCTCGATGGTCACAAGCAACGGAAAGAATAGTCAGTGAAGGTGCTAGTTGGTCTTGGGAAAAACGCCCGACTTTACTTTACAATGGTTACCAAGAGTATGTTACTGATCTTTATAAAACCTATTAGGGATAGCTGTACACAATACTATAGCTTAAGGCATAAGGCGCAAAGTTAATAGTTTGTAAGGACGAAGGCTATTTCCCTGTGTATTCTGACTCTGAATAAATTTGAGATGAGCTAGAATGTCTGGCCTAATAATATTAAATAATACCAATTGCTATATCTGCTAACTATTCGATAATAGCTAGTTAAAAGCTGAATAAAAAGAAGGTAGTCCTGTATAGTAATGCTAAGATATAAAATGGTATAATTTAGACAAATACTTTTAAAAAAATCAGCAAAGATATAATAAATCCTGATTTAAAAGTGTTAGATTTAAGTAGTCAATTAAGTTGCTAAAAAAGAGTTGCACTAATACAAGATTTATGGCTAAATGTCCAAGAGAAAATTGTTCAATATTTAGAAGGATACTTAATTTTTGATGATACAGTTATTAATCAAAAATATGCGGAAAAAATTGATAGGGAAGCTAATATGAAAGAGGTACTTGTGCGACTACAATATAGTTAGTGGTAATCCTAGATATCTCAAAAAAAAAGCGATCGCCAAAGACTAAATCCTTACCTTGCCTGAATTTGATTAGCTAAATCTCCTAGTCTCCAGAATGAAAGTAAAAATTATCATTGATTAAAGATTTGCTAAAAGTAAAACAAGTTAAATTTAGGGTAAAATAATTAATTATTTTGAAAAAAATCATCAAATTAAAGGTAGTGCTAAACAAGTAATGATTAATTATAGTGATGAATAAAATACCAAATTTCACTAATGTGATTTTTCACAGATGACAAAAAGGATAAAGTTTTTCGTACTAGCCTGAATAACCTTTGTCAAAAGGGTATTATTGAGTCGTTAAATATAAGAAGTCTTTCCTGTTTCTTTTCCTACTGCTTGATGTCTTTTACTAGTTAAAACAACATTTAAGGCTGCCCAAAAATTATCTTGTGTGATCTAGCTACCGCCACCATCCTCCGCCAACACACAAGATATGATAAACAGAGAGCAAGGACAGCCACAAAACCTTAGCTGACTCTTCATCCCATGACCCAATAGAGTTGTTAGGAAATAAGATAAAATGATTCAAGAATAAATTGGCCATAAAAATGCTAAATCTTGAACGAGTCTTAAAACAGGATAGGTTACTCAGAGCATTAACACTGATTAAACGGTAAAGCATTTGAATCTTTGTTGGAGTCCTTTGATCAAATGTATGAGCAAACATTTGTATGAGCAAACATTGCACTCGCTCACCTCGTCAATGCTCTGTTGGAAGAGCCCTTTTGGCCCGTTTACGCACCAATCAAGAGAAATTGTTCTACATTCTTTTCTACTTTAAGTGTTACTCGACTTTGGATTTAGCTGGTATCTTGTTTGATATAGACTGTAGCTAAGTATATTACTGGGTTCATCGCTTACAACCTATTTTAGAAGCAGCTCTGGGAGAAAAGAAGACGCTTTCAGAGCGTTAAATTAACAGTGTCCAATAATTATTGAGGGTTTCCCTGGAGTAGAACGAGTGATAATAGATGGCACAGAACGGCTAGTACAACGACAAACTGACTCAGAAAAACAAAAACTGATTTATTTGGGAAAAAAAAGCGTCACACTCGCAAACATTTAGTCGCAGTCAATCAAAACAAGAAAGTGCTGGTATTGATCTAGGGATGAGAAGGAAAGCTACCTTGAACTTTTTAAAGCTGAATATCAAGAGGCCACTATAGAACTATGGGAAATAGATGAACATTGTTTGGGTTTAAAGTCAATTTGATGACGAGTATGGACACCTGTTGGAGTAGAACTAACTGCAGAGGTTAACTGGCGAAATAAAGTAGTTTTGGCTCTATGGGTTTGTATCTCCGTGTGGCAAAAGCAAACTAATTGGTGGCTCCTGCCCAAAGTTAATAGTCTTTGCTGAATTCAGGTATGATTTGGGAATAGAGCGATCGCTAAACTTAAAAAGAATTTATATTATTTGAATAAGAAGTTGGCACATCTCTAAATTTTAGATAGTGAATTAATAATTTAATAAAATATTTGAGCATTTCTTCGAACTTAGAATAGCAAAGATTTGAACGATGTAACCTTGCTAAATAATGTCTTATAAAGTGTATTTTACCTTTAACTCAAACCATTTATGTTTTACTAATAATTTGATCTCCATCAGGAATAAAATTTGGGTAAACTTTCTATCCATGTGTCACATAAAAATAAAATTTCCATTTACTAATAACTTCCTATAATGGAGCAAAAATTTTGGTATTATGGTTTCCTAAAACCCATGCAAAAATACCCCATTTAAAGTTTTTTACTGCTTTCCATAGCCAAATTTGGTTTTTTTTGAGCTTACAAATGTGTCCAATTCATCTAATTCTCCTATTGCTGGAGTTTCCTCTAGAGCATAACAATCAGGTAATAGTTTTCCTACTTATTTGACCAAATTAATAATTGTGGTTTGATGCATTTTCTTGACTCTTTCAATACCTCTAAACCACATAAAATTTACATACATTTTTAGACATTCTTGTTTAAGAGCTTGAGAGTAACCTCTACCATATTCATAGCATTCTATGAAGTGTCAGCCACAATAGACACTAAAAAAGTTTTGTTTTCCTTTTTTAGGACCATTTTTATTGATATGACCTAATTTACATTTAGGACATTGCATAATTTTGAATTCTAATAAGTTGACTTTTTTGGCGATCGCTCTGTCCCCAAATCATACTCTAATTCAGCAACGCTAGTTAATATTAATATTTTTAACCAAGTGTTGTCTAACTTAGCTGAACATTTTGGTAACAGAAACAGTAAGCATATGATATTAGTATCAGACAGGGCGGGTTGGCACAGTAGTTAAAAACTAAAAATTCCAGAGGCATTGCACTTGGAGTTTCTACCAGCCGATACACCTTAACTACAATTAGCAGAACGACTATAGCCAATAATTAATGAACCTATAAGTAATCAAAACGAGTGAAAATTTATCCCAGATAGGAAATATAGTCTTTGAGCGATGTATCAACTTAATGAAACAGCGTTCGCGGTAGCGTTGCGTCGCAATATCATTTATTCAGGGTCTCACTTGTTTTCATTAGTGGCCTACTGATAATCTATCAAGTGCTTGAAGAGTGGGGTTCGCGGTAGGGTTGCGTAGCAATATCTCTCAGATTTTATATAAACGATGTTACCAGACATGATATAATATTTATCCAACTACAGAAATTACCAAGCCGAGAGTAAACAACTCCCAACATGAGAATATTGTATTTATGTTTACCAAGCTGCCACTAAGTTCAGTAATTACTCAAAACCCATTTTTGCGAGCAGTCTATGATGGCTATCACAGCCTGGACAAGTTCCCTAGTATCTATGTCAAAGTGTGGGAGAAACCTTTGTAAGCGTTTGTAGTTAGAACTTAACTTGGGCATTAGATGAAAATACAGTTGCTATTTGTGCCAAGTTGATATTTTTCTAAATACAGCCTAGATAAATAAAGGGATAAATTTAATTCTGGCTCTATGGCAAGAAAAGTGTTAGTTGAGTGCGTTGGTGAATTAAGGTATGATTTGAGTTTATAGCGATCGCGATCTTAGGCAGAAAAATTATAGAATGTCCAGAATGTCAATCAACTCACATCAATAAAAATGGCCAAAAGAAAGGAAAGCAAAACTACATCTGTGTTTATTGTGGTCGTTAATTTATTGATTGCTGAAACTTATACAGTTTATAGTGATCAACTCACAGATGAATGGTTAAAATGTATGTTAATGCTATGGGTTTAAGAGGAATATCAAGAGTGAAAAAGGTACACTGTACTACAATTATCAACTTGATTAAATAAGTAGGAAAACTATTATCAAGTTCTTACTCTCCTGAAGAAACTCCTCAAGTAGGATAGCTAGAAGAATTACAGACATAATTATGCTCAAAAAAACCAAATTTGGCTATGAACGGCAATAAATCATTTTAAAAAAGGAATTTTAGAATGGGTTATTGGAAATTGTAGTGGAAAAACATTTTATCCTTTATGGGAACAAGTTAAAAAATAGGAATGTCCTCCTTTAAGTTACAGATGGATGGAAAGTATATGCCAAGGCCTATTAATGATGGGGATAAAATTATCGGCAAAACCTATATGACCATTGTAGTTGGAGAAAATACTAGACTTCGGCAATATCTTGCCAGATGACATCGAAAGACTCTTTGCTCTCACGGGGTGACAAGTAAGCTTAATGATAGATATAGTAATTATTTGAGAGAATAAATTGAATAATTAATTCAATTAAAAAAGAAAGCTTATTGAGTTTGAGAGGTAGCGATCGCCAATTCACTCTTATCTACCATCTGAGTTGAATAATTATCCAAGCTGTATGAGAATATAATATTATTAAAAAACTCACATGAATTAATTTATTGTTAATCAAAAATTACAGTCTAATTAACCACTGTATTCATCGCTTTGAGTCCCCTTTGATAATATAGTAATTTATGAGGATTAAGGCTCATTAAATTTTCTACTAATCCCCAGATAAAATCATAATTTATTGCCCAATAAATCATAGATAATTCTACAAGAAAAATACTGTTTCTTCTTTTTTTATTCTCACTTTTTCATTAGTTATTGATATATATTTTTAACCACTTTATTTTTAATTTTTTTGGACTTGAAATGAACTAATTGTGTATAAAATAGCTATTAATAAAATTAAATTACTTAATCTCGTTTCATTAGCCTTAGCTGATTTTAGATTGTAACCACAAGTTTTATATTCTTTAAAAATTGCTTCATTTCCCATTCTCTGACTATATATTTTTTTAATCTTTTCAGGAGATGATAAATTGGAGAGAATATACCATTTATCTAGAACATATTTTTGACAATATTTCTGTTTTTTATACACGAGTAAATTATATGTTTTTGCCTTCAAAATTTTGGGTAATACATGCTTCAATAATAGTTTAGTCTCACCGAAATTTACTTTTAATTCTGAGGTTTTACAATATTTTTTACTTCGTTTAATTATCGTCGATTTTGTTTTTAGAAAACAAAATATACATCTTGCTTCTGATATTTTTTCAACCAGTGAGAT

Protein sequences of DBSCAN-SWA_1

>NC_008312|11373:91002|54555_55059_+|WP_011609939.1|DBSCAN-SWA
MSGVVKIEINESVETLKKLLKSASTAQEKERLQTIYWLKTQTVETVKEIAIMLGRNRVTVQKWLGKYRTGGLNLLLEPKKNLGGRPSSIPPNVIEKLEAELQNPEGFQSYGEIQQWLTTCFDIELSYRTVHQLVRYKLKSKLKVPRPNHIKQNKEAQENFKKNSHLN
>NC_008312|11373:91002|74762_75218_-|WP_081432519.1|transposase|DBSCAN-SWA
MKLINKYSENQLPIRYWCQDETRIGLKTITGKVITACGVKPIGLYQWLFKYLWLYGLVEPKTGDSFFYEFSHLDTPCFERFLELFSQTYPEEIHIIQLDNGRGHLGNDLSIPDHIILLFQPPYCPEVNPIERLWKEVKKFLKNRVFDSLDF
>NC_008312|11373:91002|12894_15912_+|WP_011609940.1|DBSCAN-SWA
MANELREGDKTPVDYSSLLKQILNELPTMNPFKVSSNKKILEINIDDIAACIAKTKVENPISNTISVRSATVNFASEKSFSEKIQEIKGCLETHFSSALQGENLVYFIEGLTTNLESFQGQANKLGLSYPFNEEYKGLQTKELILDSNKNGSDSILRFAKLTITVENTKKFISQLETGIKNHISDSFETDNQGEMEGALDILNSQINEESSNFNLLQKLVDQETLGKLKREAIITYLKYIEQNVDSKYKNTKGFIYLQDLIRRLKLIEEYLDEQTDDFEVYYAGVTVNYKDVFARGEAFDALPIIPIIEGNLGESRDKEVGKVQFTLGLKLKLNGKVQKDRGKTSFEYNLDIINPENSEHKAKLADPDIQSRESFAKKVLIRVFLYYFIFACDPPSLMNDELLYNPRLKFEQVLIDLKSSKHDDEKRKIFRGIVKGFSEYRVQEKVNSLCQFLINFINKKKRLPVYHENQVISISREILNKDLDSISIGDFFQEDWREGKKILKYIFIDKPGVNSYTLCQIPVIIKIEDIRYFQGDSNPKEFKFEYDIQGMKTLPMFWIPNTNPCLDNYKAYFEKEYKHILFYYDNKRLNQDRQNQEHFNSTQIFLYRFTWILLSYLCLYILLEECSEETKELLFIPMVRLHEGTPANPFHTEKFLADLSKLLCHIFNQKYLCNSQGFRVEMNKRPKNFQIRNGLNSLYSVLSKKFTLTDTSKFLNLEKLAIIIVSSRESDAKKNNKNSNDRIITLIGEVIGIEKLEDGSVKIQPLITFDNNYYLRKMYEKPPILNETVKDLYVQGYQNFLYVAQATYTSTLHITQQEQDEKLYFMSPTIIKDMKQGQKNIKIYPVFYDKYYVHPFKSLDSHSFYIQDTKQLMNISEDSSQEAVVFFNLFNGILVGNNERFYNGVISYSTLLGKFYPGVMDDADIREALVLDSQLKNDILQYLTFFHFSRFERQTKVSLKLDPYENIIGDKSVGALSIFPHLTENINFNALAFLIEVNKVVDVYF
>NC_008312|11373:91002|89556_89694_+|WP_155994200.1|DBSCAN-SWA
MAKRKESKTTSVFIVVVNLLIAETYTVYSDQLTDEWLKCMLMLWV
>NC_008312|11373:91002|72932_73316_-|WP_044136227.1|DBSCAN-SWA
MITTPKGTEIVDVIVGEKGPVSDVKILRKQQDKFDKKQKFQGDKADEGVERTTTPKKKPRKKEMPLEIKEENQEKARKRIFLEHIIRLIKIFRIARERFRLKDNNYQKVILIIYDLVRLRIGSFILV
>NC_008312|11373:91002|57893_58088_-|WP_155994193.1|DBSCAN-SWA
MEFIKYLQKQRPGNKLAIFWDGVTYYNFQAYREYLMTINQDLSEEECLINCTLICSKCSGAKSC
>NC_008312|11373:91002|59828_60332_-|WP_011609939.1|DBSCAN-SWA
MSGVVKIEINESVETLKKLLKSASTAQEKERLQTIYWLKTQTVETVKEIAIMLGRNRVTVQKWLGKYRTGGLNLLLEPKKNLGGRPSSIPPNVIEKLEAELQNPEGFQSYGEIQQWLTTCFDIELSYRTVHQLVRYKLKSKLKVPRPNHIKQNKEAQENFKKNSHLN
>NC_008312|11373:91002|23489_23666_-|WP_155994192.1|DBSCAN-SWA
MSLRKQIIRAIAKGKKKFFPPGSLFFLSFGGSSFAKASSDFFSISVYGGLENILLSKF
>NC_008312|11373:91002|25440_27636_-|WP_011609946.1|DBSCAN-SWA
MVQERPPLEEMTLRQLRKVASELGISRYSRMRKAQLLAAVIEAQGMNNLSSAPLSKLEVQERAEAKKFESGEENNIDDFFSSVDEGLTDLPNGYAKSKIVLMPRDPEWAYAYWDISNELKEELRSQGGQQLALRTYDVTDINLDSQSPHSIQEYPCDELAREWYIPIPVSDRNYTVEIGYRCADGRWLVLSRSEEVNIPPVYPSDWIDEQFITVSWDEDLRGKTFMELFPASRQITFHDNHDDIYQGMFGIAEAEDKRVSGSMFGSVQMVPGSGQMIEETLSSYAMVSGLGMWASGSNVSCGNQMMSGVGQTMSGVGLNASGVGLTASGVGLTASGVGLTASGVGLNASGVGLTASGVGLNASGVGLTASGVGLNASGVGLTASGVGLNASGVGLTASGVGLNASGVGLTASGVGLNASGVGLTASGVGLNASGVGLTASGMGMNMSGVGLTASGMGMNMSGVGLTASGVGMNMSGVGLTASGMGMNMSGVGLTASGMGMNMSGVGLTASGMGMNMSGVGLTASGMGMNMSGVGLTASGMGMNMSGVGLTASGMGMNMSGVGLTASGMGMNMSGVGLTASGMGMNMSGVGLTASGMGMNMSGVGLTASGMGMNMSGVGLTASGMGMNMSGIAGSIPPIRPRKFWLVADAELIIHGATEPDATVTIGGRPIKLNPDGTFRFQMAFPDGLIDYPIMAVAVDGEQNRSIHMQFTRETPERHTNKKEEAILEWMS
>NC_008312|11373:91002|55827_56544_+|WP_044137065.1|DBSCAN-SWA
MNKILNLEKLPTLIVSLLLLILATIIPVSSVSATGVYQMPNLDTGNRTFIVDDADVLSRVTKNKLNNTLENLANLTGNEVRFVTIRRLDYGETADSFTEKLFDKWFPTLEAKANQTLVVLDTLTNNDAIRIGDAVKIFMSNDITQSLVNETIQVPIRDGNKYNEAFLAASDRLTAVLSGEPDPGPPDIKDELSAQVAATFKSAEETNDQSATVLVVVLLVIATVVPMATYFWYQSFSG
>NC_008312|11373:91002|33064_35353_+|WP_011609949.1|DBSCAN-SWA
MNYSQPLRNSQTILGNITQMIKTIHASVNFSRLAIRPNARVPELWIEEGKATPTKKYPLLGDRYLLGRSSQACDIVIRNHLISKIHLSISRNSNKADAPYIIKDENSRNGLYNGKKKIYSLILRHGDILTLGPPALADTVKVRYIYPPAWYTQAFRYSLLGISGFTALVSLIILLEWTKFQVYPLPNPITGPVVIYARDGQTPLRPVYTNSHYELGRISKFSKYLPDAVIASEDSRFYWHIGIDPIGVVRAILTNLRSDGRREGGSTVTQQLARSIFRDYVGTEDSASRKIREAIAALKLETFYSKDDLLLAYLNKVYLGLDLYGFEDAARFYFGKSAQNLTLSEAATLVGILPAPNIFNPVQNYQIAIEKRDGVLYRMLSLGMIDQQEADRARRSLIEINPKAIEIIQSTIAPYYYSHVFSELENLLGEDLAKEGNFIVQTALNPEIQSYAERTLQDTINQVGSYASFSQGAIVTIDSRNGEVITLIGGVDYKKSQFNRATQAQRQPGSTFKVFAYAAAIEKGIPPKKLYSCSSFGWMGQTYEGCQRSSGNRNMYDGLALSENVVALRVAQQVGLDRVVKMAKGLGIKSQLSAVPGLILGQSEVNVLEMTGAYGVFANGGVANKPHTIRKIIDSSDCRDRNNIYTCRCIYSYIPDTNCENPKGDIQANQSIIQPYIASIMTQMLQDVIRHGTGRSANLGWGEAGKTGTTNQGIDIWFIGYIPNESMVTGIWLGNDDNSPTYGSSEQAAQLWGNYMKKVVNK
>NC_008312|11373:91002|48917_49433_+|WP_011609955.1|DBSCAN-SWA
MTISFVSTTKAAFLLNISTGRLRTLLNQDRVRGARKAKRLWQIPLNYRGMPEIKPGRRGPQGTWNKFQRQAKTIIHVLRKTIDYNRDNGTSYPAVAVKVGNKKDYCHALKIDGSCQIIYQPHQPNKSQAGGARLWIEVEPENIVERVYFSDGDYGPPPEVLQQRARSKEKK
>NC_008312|11373:91002|39906_40488_+|WP_011609951.1|DBSCAN-SWA
MTTGNLIIQGNKLKREGKLDEAIALYTQAINLKPDFAFTYYELGDALEKQGNFAQAIIEYEKAIELNPNIDFFHQSLETIKSRKLEQNIDLTSNQINSDFLVVGISMIKNEEDVLETFIRHNLNYLDFLVLADNGSTDNSRKIINKLIQEGFNLCVIDDYKMAHNQNNKMTNFYRRVATSLFPEFIVPMMQMN
>NC_008312|11373:91002|11373_11829_-|WP_081432519.1|transposase|DBSCAN-SWA
MKLINKYSENQLPIRYWCQDETRIGLKTITGKVITACGVKPIGLYQWLFKYLWLYGLVEPKTGDSFFYEFSHLDTPCFERFLELFSQTYPEEIHIIQLDNGRGHLGNDLSIPDHIILLFQPPYCPEVNPIERLWKEVKKFLKNRVFDSLDF
>NC_008312|11373:91002|68206_68362_-|WP_155994197.1|DBSCAN-SWA
MEQNGHKAQEQIAKLWGEEVTQQNVRDAVKKLRITGKKLMSPLLSTYYRYL
>NC_008312|11373:91002|59024_59294_+|WP_155994194.1|DBSCAN-SWA
MEVKALYLLINQNLKIIKTVFMPGQKKGKKVYGEQEGKRGKRGNLVAGRRKKEKDLIAPIIFKGTLNAVGFEQWLYQFPKVRLHIMLQE
>NC_008312|11373:91002|71366_72836_+|WP_011609965.1|DBSCAN-SWA
MQILHLNLKLKGDDSVEFRFYWDNLLEFQPVSRSLGEISDLIKKSEAEYYTYLPVDYTQTGQNLYKWLNGDKRDLDRVIHDGSSGEGIVLAIATFEGLSHLPWELLHNDEDFLVNSTPAIVPVRWVPNSGSMKVLTMDDKPKNEALSVAFMPASPHNKPKLDLVEEEISILKASQESPFSLEIEYSGCLNKLKGLINKHDKGFFDVLHLAGHAENSYLITETESGEAKYSSAEDIADALLFKNPQLIFLSACRTAYSRESSIPSMAESLVKNGFKAVLGWGDRVLDTSAIAAAEIFYQNLSSGSTVTQALAQTYRKLIETEKGWHLLRLYVKESLPGALVTASATLGRIPPHRKITTLPVKNCYYQLKQCVSILKQDSKKGVLILGKSNITSLFTDGLCERLPKSKIVKLDQQIDEYEFVNKLASELENSEQRNALRNAFQRGDKLKYPLRDLFKKRNETGLEPLDISKNTQTFILTIFSGAIATYEDS
>NC_008312|11373:91002|17125_20872_+|WP_011609941.1|DBSCAN-SWA
MKITDNLGFLFEVGFNIGILADIQHQKYQNNFGDLYVRDLQQLKLPRMVKRMSQNHSIIDPESIKNLEIWSRYFILKGFLGGLIFFREYIKSTKWNLEPKKLKILYYQCCFHGDNSLGTNNKDKLLGIEELLSQFLSVDDLNTNLNRYVNQYLGKKGEFLQADTLILLGDDQQLRIICVDMSIFSVASEKDLVPLNDNKLNNLRKILMTDIKHIHSKSVFSKLRIDTGNTKDFDFVFSSDFKSFFTAFKRKDKETTKLIQAGAYAESFYNFLLKETQIITDKKSVLFNIVGYSDRNISTLCLRPENLNILTTCSEIYKKEDKNKETKVARRKVLDLIKNRAVFSFINGKALTENLKTKKLNFSGDGIARVIHEEKLNDFVNSIDVISDKLAAKLGLKLGLNLRDAHAELIEKALISDNTFVFLTGNPGIGKTTAIANFLKSHLEEGFLFFYISPRIQVNLDLIHKFKSENAQDQELFDDRLFCINTNSIIIQENDNYSTVRYYSNQRQDDFTSKNVRFINYNSQAEPRKQRQRNFHRITVDKIENRKKITAGVLDSVCKGIYAIINDKISNNIVATVSTQSLKITPNGRDTIEHLKTIFKSTYDRKRGVNPDKMYEISQRIKHLFIMIDEITGDDSGVHFLKGINKFLGQYQLTNSEYGFNTKVIVADASIVEQEVIQQHLSQESPEPDKIYFRAAKSQAEALSVQDFQFKNKRAVTINANSYPASSLNITYKVFIQSINFNQYDWKFKEKNQLTKEVDLEILSDIKYFLENYSSSQLLVYIQNKKRLKSLIKNIKESHKNFDEYTDYLEIHASLYDEKRKKIDKYKQDVKIVFMTSSASRGLSFPKAKKILVEIPRFQIEKNLMEVIQVIYRARGQYQENGKKITLDDQEKEIIFYFSDSAIYYPKDNDTSLENYDEERTLSLEESTMNLLDMLLILKLSIMTRIVGAGNLGSKKFLMVPIGGKSISTAGNSFSEKMTNLIRELKNEHNRHPEKQSLQYVYSSLTQILKEAVFSLPNSNSDSKNITYLSLIGFLKTELPTLFNRLDKFLNFGNIETGHLTGNLLVVPIYNQALEETYQIELENQIRRFANNELVNKMLSIMKSKDYPPNIKSAIESPLELIKILKGDKGNINTTQWFEQNSNNLDQYYAVPLFVFISGELMSKYFKQELEEEEEETAFRTLLSKYIHSLYPAYNTLPIGRKYKEFPFIVFRSYSLKEIREKIYSDRYLLTSNELNVLNLILSREERS
>NC_008312|11373:91002|78444_81126_+|WP_155994199.1|DBSCAN-SWA
MLELIRTPFLLYVLSSTLVSIYQQNPSSISQGIEAIYKAVSNLEKLLDKFVREQYKRESGKSKIPIPWSLNKVKRLLGQIAVLMMSDREPDDNEILPEHFNKVIQIQEDIKKFIDLTKNLYLLESEEKANNQNPTSTYKFRHLTLRDYFAFDYGSNFFDQQEDNFNQKSEKFKLEIEPEQVVKAIGKIEKEQVVKLLTKLLDHPDPDVRYEAIKSLGELRTLVYVEGYNSDLKNQVVNYSLDEFDKSLIKEYFSEKKYFEINDNEAKKIYQYSGGNVWIIEQIATMFGVVSLDEILGVDDVPMPIAAKSPDEQILATTVQRLLHYCVNKEDKRAVYLLAIAYCPNPEFLKFMLGCENLDAKLQELHNNYPFILPEKQQLEEIHQKFTKQYLLSLRNENNFNKYESESQKIAKNLNRKAAHYFQDKIEDLTGKLTTAKQRFRNEEFPDFIINWFYHRFWLSSKDNVEYIWNDMIPYLVEGWRYNNNFVIELLKIAGEFDKDYEFFQLFKAVFMERKDPYSLVKKLVEKSDKTTKKDEWVAIVLLIYCDFLYEEKKYSEVLKRWEQAQIFIPEEAEDLRRSFEKLRSLSFKQEKKNDFKEDQIETESSPPIDLSKNIDLGKVSSDILSRLEKLENQRNTFSQQATQKEEKTELQLKQNYHPNEEKIEEDKEQKFNSQTWSEKQANIPKKEKTESQLKQNYHPNEEKIEEDKEQKFNSQTWSEKQANILKSDNEKLIYQLKFWHLIVLIFPLYIIILVFFFLVYLIYEQNNMPEKIQIRNEQNNMPEKIQARNEQNNMPEKIQPKNEQEYKKLNEQENENLIESAIFFAKNNRVDKGLENLCEIPRNSNSFREAKQWINRWSKDDYWGPQLPSIIEKFQEEGLSCPAAEDADLRRY
>NC_008312|11373:91002|74353_74533_+|WP_011609968.1|DBSCAN-SWA
MSIHKLICPSCGSNHIVKNGTIHNKKQKYQCQNCQRQFVENSQRDYISNETKELIDKLK
>NC_008312|11373:91002|55067_55523_+|WP_081432519.1|transposase|DBSCAN-SWA
MKLINKYSENQLPIRYWCQDETRIGLKTITGKVITACGVKPIGLYQWLFKYLWLYGLVEPKTGDSFFYEFSHLDTPCFERFLELFSQTYPEEIHIIQLDNGRGHLGNDLSIPDHIILLFQPPYCPEVNPIERLWKEVKKFLKNRVFDSLDF
>NC_008312|11373:91002|36829_38158_+|WP_011609950.1|DBSCAN-SWA
MPHTNQTERKYYSHYSDDQIRQIVVEKYKTCLEKFGYLFELEIKYKFDKNYQIKISIPIYKKFMVPVINNFISKANKLKKEEKLDEAIALYKQAIELNPGFPWYYYELGETLTEKGDLDEAIAQFFQATKINPNSAWFCYELAKALQKKGELNQAINYYRQAIESNPDFYGFYNSLGCCFFQNKNYHQAIINFLIALELNSSSVISYEYLYQVYLQLGLTKKCIDNLFGRFKQPSQKPTLTIRIKEKSVNSKQELSKTKIFGIGLGKTGTTTLGACLNNLGYKHYGWYTLTNHKLLYQIKLDNFDDVHRVVNQYDCFEDYPWPLIYKWLDQKYPNSKFILTIRKCSQTWFKSCLNHYFRLQDRAAYLYDLIYGLGHPQNCSDEYINFYESHNQQVIDYFQSKPDKLLIICWEKGDSWDKLCGFLGKTVPEILLPHLMKSQTN
>NC_008312|11373:91002|21245_22433_-|WP_011609942.1|DBSCAN-SWA
MRVILMTGKGGVGKTSVAASTGLRCAELGHKTLVLSTDPAHSLADSFDMEMSHEPRKVKENLWGAELDALMELEGNWGAVKRYITQVLQARGLDGVQAEELAILPGMDEIFGLVRMKRHYDEGEYDVLIIDSAPTGTALRLLSLPEVGGWYMRKFYKPLQGMSVALRPLFEPIFKPITGFSLPDKEVMDAPYEFYEQIEALEKVLTDNTKTSVRLITNPEKMVIKESLRAHAYLSLYNVSTDLVVANRIIPDSVSDPFFKKWKENQQQYRQEIHDNFRPLPVKEVPLYSEEMCGLAALKRLKETLYGDEDPSQVYYKENTVKVVQEKGNYNLELYLPGIPKEKIQLNKTGDELNIRIGNHRRNLVLPQALASLQPVGAKMEDDYLKIRFAEVAKV
>NC_008312|11373:91002|28953_30639_+|WP_011609947.1|DBSCAN-SWA
MPENLRSQLVTKGVQRAPNRAMLRAVGFEDSDFTKPIIGVANAHSTITPCNMGINDLAMRAVSGVKEAGGMPQIFGTITISDGISMGTEGMKYSLVSRDVIADSIETVCNGQTMDGVLAIGGCDKNMPGAMIAIARMNIPAIFVYGGTIKPGNYNGKDLTVVSAFEAVGEYSAGKIDETELTEVERRACPGAGSCGGMFTANTMSSAFEAMGMSLMYSSTMAAEDAEKADSTEKSAHVLVEAIRKQILPSQIITRKAIENAISVIMAVGGSTNAVLHLLAIAYAANVKLSLDDFEIIRARVPVLCDLKPSGKYVTTNLHQAGGIPLVMKMLLEHDLLHPDALTITGKTIGEQLTNIPSEPPSNQDVIRPWNNPMYAQGHLAILKGNLATEGAVAKITGVKNPEITGLARVFDSEEACLEAILAGKIQAGNIIVVRYEGPKGGPGMREMLAPTSAIIGAGLGDKVGLITDGRFSGGTYGMVVGHVAPEAAVGGTIALVKEGDMITIDAHKRLLQLNISDEELEKRRQVWKPRKPQYTRGVLAKYAKLVSSSSVGAVTDAGLG
>NC_008312|11373:91002|60808_60946_-|WP_155994195.1|DBSCAN-SWA
MVATDIIVKITGIRKRKQRKIIDELDDFINQKKELKEIKIALKLK
>NC_008312|11373:91002|63116_63416_-|WP_011609960.1|DBSCAN-SWA
MRKSSKSKGRLVWNHSTHIEGLIRILDKLTQHKGIETVTPGVIGRSKSHIPHIKLKISVPIRGGFKLIARQGKTVQEVFILTSLTQEDLEKLITQVLAK
>NC_008312|11373:91002|84931_85924_+|WP_011609974.1|DBSCAN-SWA
MPLIHIKKSWEIPEREITPEKVYVNRRRFMKNLIGTGISFTALSTLTSCAENSKKSPTYEAVNLPKISNFTPNYNFAKLESSITDEALGTKYNNFYEFGGTKSIWKNAQALPTENWQVEVTGLVKNSRIYDIDELQKRFPLEERIYRFRCVEAWAMVIPWLGFPMKLLMADVEPTSKAKYVRFTSFYDPQITKGPGFWASDYPWPYTEGLRIDEMANELAFFAMGMYGKLLPKQNGAPLREVIPWKYGFKGAKSIVKIEFLEQRPATFWNTLIPNEYGFEANVNPEVPHPRWSQATERIVSEGASWSWEKRPTLLYNGYQEYVTDLYKTY
>NC_008312|11373:91002|22679_23072_-|WP_011609943.1|DBSCAN-SWA
MDIISRLKQDYQKFPADQTYSIYAENVYFEDPLNKFRGIERYQKMIGFMNNWFNDIKLDLHDISQSGNVIKTRWTLSWTAPVPWKPPMAIPGWSELKLNADGLINSHIDYWDISRLDVLKQLFQLRSFPV
>NC_008312|11373:91002|66564_67806_-|WP_011609962.1|DBSCAN-SWA
MSDWQVITGGVTAPKGYQATGITAGLKPSGAEDLALILSNVDAIAAGVFTTTQVRAACVDYCRQCLENKPSARAILCNAGQANAATGDLGWQDAVESAKELGKALNISPELILLASTGVIGQRIKMDALKAAIPKLVSTVSQEGGEAAAKAIVTTDLVTKSIALETLMGDRVVRIGGIAKGSGMIHPNMATMLSFITCDAAVSPQLWQDMLTTAVNRSFNQITVDGDTSTNDTVIALANGQSRTSAITNMGAEAKKLEAMLTEVCIYLAKAIARDGEGATCLIEVQVTGTSNEVSANKIAKTIAGSSLVKSAIFGRDPNWGRIAAAAGRAGVKFDHKELQVKLGDILLMENGQPLDFDLAAAREYLKQRAAGKYLLDDTVLITVKVGDGVGSGKAWGCDLSYDYVKINAEYTT
>NC_008312|11373:91002|40835_41411_+|WP_011609952.1|DBSCAN-SWA
MLERFKSRDTKGECYQWYDLYIKIMRGEKFSNSDLTYIALNYAQKVEVKEDCLNHVELEPPTIKSSQLSYSDLIAKNDYRTNVITTIIKSWENQIIKIPPLISREDLIPFSESPTSPSTDNHQHGVFEPNFHLEKLFIDIPPFEYIYQRFLPENILDIGCGVGQYLKIFNKRGVTEIIGVDGFIPQQSFLN
>NC_008312|11373:91002|56598_56982_-|WP_011609957.1|DBSCAN-SWA
MNITFEELNTIDKKLSKRHIDLDPGGYFIIFIDKKAGLIFAKHFTNIIDSRGLAIDPETGKPIPAKGKVERQENAIFTAKTAKEMCVKIFEETRPCHITMLDHAAYLGREFVRAEIALLSGKEYIQD
>NC_008312|11373:91002|31433_32471_-|WP_011609948.1|transposase|DBSCAN-SWA
MNIIDKLNNFINQTKESKEIKRALAVKMTLSGKSYHEVKELLNVSHSFISEWKNQALFHGVESLRLQYQGRQGYLKTVEKEKTIEWLRAQDYLRLSDLKNYLQEQYDVVFESNQSYYNLFKEAGISWKKTQKKNPAKNDELVEVKRKEIEEFLAKWQPEIETGKLTVFMIDECHLLWGDILGYAWGKTDERIEIAIKNEKERQTYYGALDYKTKEFLVQEYESGNTKNTIEFIKYLQKQRPGNKLAIFWDGATYHNSQEFREYLMTINQYLSEEELLINCTRFAPNAPEQNPVEDIWLQTKNFSITFYHLCSSFKVVKWLFKFFADGQIFNFPKLFQYEILPQPT
>NC_008312|11373:91002|75226_75730_-|WP_011609939.1|DBSCAN-SWA
MSGVVKIEINESVETLKKLLKSASTAQEKERLQTIYWLKTQTVETVKEIAIMLGRNRVTVQKWLGKYRTGGLNLLLEPKKNLGGRPSSIPPNVIEKLEAELQNPEGFQSYGEIQQWLTTCFDIELSYRTVHQLVRYKLKSKLKVPRPNHIKQNKEAQENFKKNSHLN
>NC_008312|11373:91002|11837_12341_-|WP_011609939.1|DBSCAN-SWA
MSGVVKIEINESVETLKKLLKSASTAQEKERLQTIYWLKTQTVETVKEIAIMLGRNRVTVQKWLGKYRTGGLNLLLEPKKNLGGRPSSIPPNVIEKLEAELQNPEGFQSYGEIQQWLTTCFDIELSYRTVHQLVRYKLKSKLKVPRPNHIKQNKEAQENFKKNSHLN
>NC_008312|11373:91002|62233_62407_-|WP_155994196.1|DBSCAN-SWA
MSGILKFVIGDRWTVTFTILWQMIQDWACFLYITYGYNVYPYLIENCERKVSKTAMT
>NC_008312|11373:91002|90561_91002_-|WP_155994625.1|transposase|DBSCAN-SWA
MSLVEKISEARCIFCFLKTKSTIIKRSKKYCKTSELKVNFGETKLLLKHVLPKILKAKTYNLLVYKKQKYCQKYVLDKWYILSNLSSPEKIKKIYSQRMGNEAIFKEYKTCGYNLKSAKANETRLSNLILLIAILYTISSFQVQKN
>NC_008312|11373:91002|73893_74169_+|WP_155994198.1|DBSCAN-SWA
MKKISNPNTQSEALSHLGVTIKNHQLKIEFSETGNPYAEPDGDRTKVSDTSTQTVTVELILDTPPPSTLKLQTEVSPFTQGWSCICSDKPI
>NC_008312|11373:91002|81364_81982_-|WP_011609972.1|DBSCAN-SWA
MYRRCIQLTSLFLIPNLSHNTSLLISFFSINSKNAVMAKIKLKILIINLLVSLAFAKPVVAYIKWQAQTLKRSRECFYCDLSKINLSNSNYKKMNVTGSVLQNADFSNTNLEKANFTNTDLTEAEFDSANLQEANLQRSILKRTNFWGANLQKANLRGADLTETIFWNADLRDADLRDTNINNASFIDAQLKGAILPDGTVYPYK
>NC_008312|11373:91002|68746_70330_-|WP_011609963.1|DBSCAN-SWA
MAIGYLSFVLHAHLPFVRHPERDYVLEEEWLFEAITETYVPLIQMFEGLKRDGINFKLTMSLTPTLVSMLRDPLLQGRYEHHLTLLQELADKEIDHNIHNGHLRYLAEHYVTHFNNVRKLWERYDGDLITAFKQFQDSNNLEIMTCGATHGYFPLMKMYPQAVWAQIEVACQHYEENFGRRPTGIWVPECAYYQGLERLLADAGIRYFLTDSHGVLYARPRPRYGSYAPIFTETGVAVFSRDHESSQQVWSSQVGYPGDSEYREFYKDLGWEAEYEYIKPYIMPDGQRKNTGIKYHKITGRGLGLGDKQLYDPYWAREKAAEHAGNFMFNRERQVEHLYQIMEQLPIIVSPYDAELFGHWWYEGPWFLDFLFRKTWYDQSTYRMTHLADYLQKHPEHQVCLPAQSSWGYKGFHEYWLNHTNSWIYPHLHKATERMIELAQYEAQDELVLKALNQAGRELLLAQSSDWAFIMSTGTMVSYAVRRTRSHLMRFNKLYEDILQGKIDSGWLEKVEAIDNIFPQVNYRVYR
>NC_008312|11373:91002|58846_58939_+|WP_155994624.1|DBSCAN-SWA
MQSRSLSDRAKKFGVNQSAIFYALKIMDFP
>NC_008312|11373:91002|82491_84570_-|WP_011609973.1|DBSCAN-SWA
MNYRINSQNQNPEDADKNIVSQNETIVGTSKCPPILKERYQVIKPLGESVWNHTFLAIDHDKPSKPPCIIKEFVNLDDIKDLVFQSQEVIPTFFSCDPVQLDKIGKHPHIPELLASIEHDGHHYLVQEYIEGSNLATELIEYGVFSESKIWQILNQLLLVLELIHDHHLIHGDIKPENIICRRKQGTNTQEFVLVDFGVTISATGDLFSIGSINGSAEYAAPEQTQGKVYPNSDIYSLGVTCLHLLTMVSPFELFDIKAEKWVWQDYLKHPISRHLGRILDKMIQRDHRQRYQSAAEVIKDIKYGPTPADVILQKQNWNVTIWGGVAIAMLSLVISSRVPSAKPRPSLSPSSNTTTIPNEERSFPRPKIKEEYKNTLPSLQPYTGVGDKLSPLRTLATTSGPVWSITTSPDGRIVASGSTNGSIQLLHLRSGQNLGQLSGHDGPIWSVAISPDGRTLVSASGDSTLKIWNLYTRRLKNTLSGHLQDVLSVAISPDGNTIASVSKDKTIKLWDINSGLLLYTLYGHLDVVQSVAFSSDGKTLASGSNDGTVKLWNWRDGRLLSTLKGHRKPVWSVAISPDGKTLASGSWDKTIKLWEINNNSFQRVIRRSQRTLIGHSEKVQSLQFSPDGETLASGDFDGTIKLWQIKTGGLMGTLKGHSAWVNLTFDPRGKTLISGSFDDTIKVWRFSPLRF
>NC_008312|11373:91002|41474_41900_+|WP_011609953.1|DBSCAN-SWA
MCLEVAEHLPPGKELNLIEILNNHASNILIFSAAEIGQPGNGHINCQPFEYWVDLLKQNWSPMLTETLFFRCISSFSSFRRNPIVLQKKTELTSENSSLKSWDKLIVISQIPYKWYGQKSQIISEILEIDIPDDIYSYSTK
>NC_008312|11373:91002|73444_73828_-|WP_044137067.1|transposase|DBSCAN-SWA
MNPTLEYIYNHPKETKRIIGITYEQLIKLIAKAQVIESEKKEAIAKTEKRLIKAGGVRKKNLTKEEEIILTLFYLHQIPTFQTLGINFGISESSANNIFHYWIDILRELLPASLLEQVKKKKMNWNG
>NC_008312|11373:91002|76284_76875_+|WP_011609969.1|DBSCAN-SWA
MVTQADPNLNISKTGLEANFFILEKRSFKNRPDLLPESSENNLPNEKPFETLYDAFERYKRLVLLGEPGAGKTVALQEFKKNISKKERQAENNSLVIFVSIQKWKYPADIVTFLAKEIGKIEEDFRKEIQTKRLLLLLDGLDELPSNVSKRSESRDAEIIDYRVHFLSKLSDFLRNLNPNNISIVMTCRNGTLVKK
>NC_008312|11373:91002|58677_58878_+|WP_155994623.1|DBSCAN-SWA
MSFVENGGTITKAAHTFGIARSSIYRWLSRPKLSATKVKSRQRKLDWKALEKDVKPNPESLIVRQS
>NC_008312|11373:91002|59364_59820_-|WP_081432519.1|transposase|DBSCAN-SWA
MKLINKYSENQLPIRYWCQDETRIGLKTITGKVITACGVKPIGLYQWLFKYLWLYGLVEPKTGDSFFYEFSHLDTPCFERFLELFSQTYPEEIHIIQLDNGRGHLGNDLSIPDHIILLFQPPYCPEVNPIERLWKEVKKFLKNRVFDSLDF
>NC_008312|11373:91002|23798_24329_-|WP_011609944.1|DBSCAN-SWA
MPLLELTLTQLWNKQTNAKLTHNIYEEIGGVKKSIANHAKEVYEQLNDEKRKKLEQIFIQLINLENLKAYTLRVKNYTNLGEDNWELITYLNSENISLVIINYNLRKILRDNGSNLSEPNLEEDKFNSAHAPKAQFQVADISKADLSNANLDGTNFSRAKLNEANFSKAYMPNVNC
>NC_008312|11373:91002|64427_64763_+|WP_011609961.1|DBSCAN-SWA
MNNIPGSPSKNFFSQSNSSNLLWQYVQSMNPETVAQLSKPAPEVAQIMEQNLRGILGNLPPENFSMAITTSRENLGQLLASAMMSGYFLNQAKQRMELENLSIPFTNDKNE
>NC_008312|11373:91002|65607_65727_-|WP_081432365.1|DBSCAN-SWA
MCSFVGNKNNKQWLWLAIDIETKEIVGFYLGERGEKGAA
>NC_008312|11373:91002|45500_48125_-|WP_011609954.1|DBSCAN-SWA
MSTLVIVESPTKARTIRNYLPSDYRVEASMGHVRDLPPSAEEIPEKFKGEKWAQLGVNVESDFEPIYVVPKDKKKTVKELKDALKEVDELLLATDEDREGESISWHLLQLLKPKVPTKRMVFHEITPEAIRRAIDNCRNIDEQLVRAQETRRILDRLYGYTLSPVLWKKIARGLSAGRVQSVAVRLLVNRERQRQAFKRGGYWDLKASLEQEKTPFESKLVTLGGTKIATGNDFDENTGKIVEGRNVILLDEAHAEALKEQLQHKPWTVNSFDERAVRRKPSPPFTTSTLQQEANRKLRMGARQTMRTAQNLYEQGFITYMRTDSVHLSDEAIAAARSCVEKMYGPEYLSSEPRQYTTKSKGAQEAHEAIRPAGKTFRTPQETGLKNQEFALYDLIWKRTVACQMADSRQTHITVNLQVEDAGFRSNGKRIDFPGFLRAYVEGSDDPEVSLENQEVPLPAIKQGDHPACTEIEVVGHETQPPARFTEASLVKTLESEGIGRPSTYATVIGTIVDRGYAKLQSNALVPTFTAFAVTTLLEKHFPEFVDVKFTARMEQTLDDISMGEAQWVPYLKKFYFGESGLDTQIKEQENQIDPKLARTIELDNLDANSEMTYRICIGKFGAYIEAENGENIVKASIPEDLTPSDLDPEQIEKLLKQKTEGPQELGIHPEEDKSIYIMTGRYGPYVQLGDDSEGSKRKPKRASLPKGVNMEDVTLDLAVGLLSLPRTLGTHPETGCKIQANLGRFGPYIVHDQGKEDGKDYRSLKVKDDVLTITLERALELLAQPKRSRRGSAKAVLPLKDLGKHPEDGETVGVYDGRYGLYVKHGKVNASLPKDMSVEDVTWEKALELLHAKASSKKSARGRKSTKSKAENN

Homologous phage analysis in the prophage region

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_081432519.1|11373_11829_-|transposase	IS630 family transposase	NA	NA	NA	NA
WP_011609939.1|11837_12341_-	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_011609940.1|12894_15912_+	hypothetical protein	NA	NA	NA	NA
WP_011609941.1|17125_20872_+	ATP-binding protein	NA	NA	NA	NA
WP_011609942.1|21245_22433_-	TRC40/GET3/ArsA family transport-energizing ATPase	NA	NA	NA	NA
WP_011609943.1|22679_23072_-	DUF2358 domain-containing protein	NA	NA	NA	NA
WP_155994192.1|23489_23666_-	hypothetical protein	NA	NA	NA	NA
WP_011609944.1|23798_24329_-	pentapeptide repeat-containing protein	NA	NA	NA	NA
WP_011609946.1|25440_27636_-	DUF4912 domain-containing protein	NA	NA	NA	NA
WP_011609947.1|28953_30639_+	dihydroxy-acid dehydratase	NA	NA	NA	NA
WP_011609948.1|31433_32471_-|transposase	IS630 family transposase	NA	NA	NA	NA
WP_011609949.1|33064_35353_+	PBP1A family penicillin-binding protein	NA	NA	NA	NA
WP_011609950.1|36829_38158_+	tetratricopeptide repeat protein	H8ZJ35	Ostreococcus_tauri_virus	1.5e-06	28.2
WP_011609951.1|39906_40488_+	tetratricopeptide repeat protein	NA	NA	NA	NA
WP_011609952.1|40835_41411_+	class I SAM-dependent methyltransferase	NA	NA	NA	NA
WP_011609953.1|41474_41900_+	hypothetical protein	NA	NA	NA	NA
WP_011609954.1|45500_48125_-	type I DNA topoisomerase	A0A1V0SCS0	Indivirus	3.3e-109	32.6
WP_011609955.1|48917_49433_+	hypothetical protein	NA	NA	NA	NA
WP_011609939.1|54555_55059_+	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_081432519.1|55067_55523_+|transposase	IS630 family transposase	NA	NA	NA	NA
WP_044137065.1|55827_56544_+	methanol dehydrogenase	NA	NA	NA	NA
WP_011609957.1|56598_56982_-	DUF4346 domain-containing protein	NA	NA	NA	NA
WP_155994193.1|57893_58088_-	hypothetical protein	NA	NA	NA	NA
WP_155994623.1|58677_58878_+	hypothetical protein	NA	NA	NA	NA
WP_155994624.1|58846_58939_+	hypothetical protein	NA	NA	NA	NA
WP_155994194.1|59024_59294_+	hypothetical protein	NA	NA	NA	NA
WP_081432519.1|59364_59820_-|transposase	IS630 family transposase	NA	NA	NA	NA
WP_011609939.1|59828_60332_-	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_155994195.1|60808_60946_-	hypothetical protein	NA	NA	NA	NA
WP_155994196.1|62233_62407_-	hypothetical protein	NA	NA	NA	NA
WP_011609960.1|63116_63416_-	hypothetical protein	NA	NA	NA	NA
WP_011609961.1|64427_64763_+	DUF760 domain-containing protein	NA	NA	NA	NA
WP_081432365.1|65607_65727_-	hypothetical protein	NA	NA	NA	NA
WP_011609962.1|66564_67806_-	bifunctional ornithine acetyltransferase/N-acetylglutamate synthase	NA	NA	NA	NA
WP_155994197.1|68206_68362_-	hypothetical protein	NA	NA	NA	NA
WP_011609963.1|68746_70330_-	DUF1957 domain-containing protein	NA	NA	NA	NA
WP_011609965.1|71366_72836_+	CHAT domain-containing protein	NA	NA	NA	NA
WP_044136227.1|72932_73316_-	endonuclease	NA	NA	NA	NA
WP_044137067.1|73444_73828_-|transposase	DDE transposase family protein	NA	NA	NA	NA
WP_155994198.1|73893_74169_+	hypothetical protein	NA	NA	NA	NA
WP_011609968.1|74353_74533_+	hypothetical protein	NA	NA	NA	NA
WP_081432519.1|74762_75218_-|transposase	IS630 family transposase	NA	NA	NA	NA
WP_011609939.1|75226_75730_-	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_011609969.1|76284_76875_+	NACHT domain-containing protein	NA	NA	NA	NA
WP_155994199.1|78444_81126_+	hypothetical protein	NA	NA	NA	NA
WP_011609972.1|81364_81982_-	pentapeptide repeat-containing protein	NA	NA	NA	NA
WP_011609973.1|82491_84570_-	protein kinase	A0A1B1IUU3	uncultured_Mediterranean_phage	2.0e-08	28.0
WP_011609974.1|84931_85924_+	protein-methionine-sulfoxide reductase catalytic subunit MsrP	NA	NA	NA	NA
WP_155994200.1|89556_89694_+	hypothetical protein	NA	NA	NA	NA
WP_155994625.1|90561_91002_-|transposase	transposase	NA	NA	NA	NA

Sequences of DBSCAN-SWA_2

Nucleotide sequences of DBSCAN-SWA_2

>NC_008312|1384182:1469674|DBSCAN-SWA
TTCAAGGAGATATAATATTAGGAGTAGGTTCCTCTAACTTAATAAATAACGCCCGATACACAGGCTGATTTTTGCCTAAAGTCACCTTTTCTCTTTCTGATAAAACTGGCAGAATATTTTCTTTTAACCAATCATTATAACTTCTATAAAATGAACCATGAGCCGAGAAGCGATTACACATTTCCTTAGCTACTTTTTCTATATCAGAATGCAGAAAAACTTCTCCCCCTACTGTTAAATAATTTGCTAAATCTTCCACTAATTTTGGTTGTACAACTCGACGGGTTTGATGACGTCTTTTAAACCAAGGATCTGGAAATAAAATAGAGACTTTTTTTAAAATTCCTTTTGGAAAAGACTCAAATATTTTTCCCAGGGAAATATTCGCATTACAAAACAAATAATGCAGATTATTTAAACCCTTTTCATCTCGCCAATTATTAGCTTCTATCACCAAGGGTTCCCGTATTTCTAAACCCAGAAAATTCCACTCAGGTTCTACCTGTGCCATCTGCCATAAAAATCTCCCTCTAGCACAACCAATATCCAAATATAATGGTTTCTTTATATCTGCATAAATATCACTAAAATTGGGGATAGTTACTGACTGTTGATATTTGCTAGCTAAAGGGTTGACATGCTGTCTAATTCTTACTCTTACCAAATTTTATGCCTCCATTCTTACAGTCGATCTCTCTCGACTTTAGCTGATTAATAATTAGAGCTTACTGAAAAAGTTTGTTATTGAAGGAATTAATACCAATTGACTTGAAAATAGCGTAAATAACACATTTAATTTAATAGATATAAATTTCCTGTAGGCTTTTTAAAGCTCTACCATTAATCTACTTAGAATTCCATATTATATACCTTTAAACTAATTTTTTAGACTTTTCCAAATATTTGTAGTTTAGAGAATGCTATGCAAAAATATAGACAAAAGTGGGAAATATAATTTCATTATTAATGATGGTACCGGATATCAAGAGAAACTAAGACTTTTGGGTTCCCCAGAAATTATGAGTTGGTATATTTATTGCTTCTGTACAGTTATTCTAGACTCAAACATCTACAAAGCTATTTCGACCTTTGTTCAAGCTGTTCGTAAAGCTTTTTTGGGTAAAGATAGTTAGCTTTTTATGTCACCCAGGGAAACATAACCCTAAAATTCAAATTTTCTATGACAATTTTGCCATGGTTTTCGGTTAAGTAAATTCTCAGTTTATGAAGTCCGTTTTGACGGATGCTTACTACTTTTCTCAGCAACCTGGCTATCTTCAGTTGTGCTGCCTTCAAGTTAGCATAACCCACCTCTTTTGAGAATTTAGGTATTGCATTTGAGATAACTTAGCTTCAAATATATGAATTGGTTTTCACAATTTTAAATACTTTTCCATCACTTAATGTAGCTAAAGTGTTCACTCTTAAACCTACACCAACAATATCAGTTTTTTTTGGTGTTTTTACGACCTAAAATTCATAGCTAGAAACGAGAGACCAATCACCTACTTTTCTGCTAATAATAATTTTTTTAGTTGTTGCCTCTGCCGTGGTTCATAAGTTTTTACCATACCAATAAAAGGTAGTTTATGATTCCATCCATCTAATTCTATTGGTTTTCCAAAATTATCAATTGTAAAAGAATCAGACTTACCTTTTTTCTTAAATATTGGATACTTACCTAACTATTATTTGCGAAGTATTCCGAAGAAAAAAACTCTTAAATACTTTAACTAAGTGGATAAAAGTATATTCATAAACTCTAGACAAAAAATTTTTCATCCAGGGTATTAGTGGTTTTGTATGATTAGTAAAAAACCTCTCTGAGTTTACGGACATTGGGTTGATAACCATCTTTATATGCTGCATTCGTTCAAGCTTAAGTCCCAATAATAACAACATCGTGAGTAACCTGCGTATTGAGCCATCAGGATTTTCTGTTTATTATTAAGTTTGAGTTTGGTATGAATTGATTCCATGTATAACTGAGTACAGTTCACGAGAGTAGTAAGTAATTTCTTGCTATGTTGTATCTTTATTCTTTGACTAAGTCAATGCTCTGGTAACTCTTTTTTTAGTTTATAACTATGATTTTTGGGTAGCCAGAAATAACTATCGTATTATACTGCTTTATAAGGTAAATTTTTAGCTATCAAAACTATCCATCTACATTTTTCTGAGTTATTCCTGTTAGATAATATTTCTAGAAATCTGTATTATTAAAATTAATCAAATAAACATTTTTTGATTCATAATAAAACTGAAGCGAAAATAAGAGTAACTTTAATTTTTATTCTCTCACTTCAATAGAGCTAATAAACTTCCTTTAATATTGATATTGATAATAATTAATTTTTTATTTTTCCCTATATTTGTGGGGAGTTTGATACTCTCTTACTATGTCATCATACTGTAATAGTTGATAGACAGAATTAACACTACGTTCATCTAAAGTATTAATTAAGTAGCTTTGATATATTTATAACCACTATTACCAATTTTTTTGAAGTCAACTTCATAACTAAAAGTAACTTTTTCGCCCCAAGTATTTTGGATTTCTGCTAAATTCTAAGCTAGTGCAAAAGGTTTCTGTCCAGATGTATTAGTTGTACTATCTATCCCATTACCATTACTACCACCTTATTTTACGCCCCGTTGAATATATGGATTATTTTCAGATAAGTTATCTCTCTTTCCGTTGCTTTCTCTGCTTGACCCCATTTTCCTTAATAATTACCCATTTTTTATCCCTTGAGTAATAGCAAATACCCCAAGGTTTATAATCTTCCGTCTCAAAATTCCTTGCCCCATCATCAGTTAGACTATCTTGATACATTGATAAAAACGATTAGCCGAACCACCAGAAACAAGGTAATATTAGTCATTATAATTAGCACCCGTATTTCTGTTGTCAATAGCAATTATTTCATATGACATATTCCACCCTAACCCCAAAAGACCCGTCGGCACTTCCATGTTCCAAGTATCCACCATATTTTGAATGTTACTTTGGTACGTGATGGCCACTTTGACATCCAAATCACTGCGACCCGGAAGAGACATTAGTTCTAAAGGAAGATTAGATTGACATCTCACCGGAATATATTAGCCACATTAGGGACATTCCCTACGCTTCCGCGATCCATCTAAAAGGTTCCGGTAGTAAGAAGTTGAGACAAAGTACTCGGAGAATAATTACTAGACACCATCAATACTAAGCTTGTGTAGAATGTTAGAAAAATGATGATATCAACTAAAGTATTGTTTGTGATCAAACGTTTATTAATCAACTTAACTAATAATTAAAATGACCATTACTTATACATTTTTGGGTAAAGGTGGTACAGGTAAAACAACCATTGCATTTGCCACTGCCAAAAGATACGCTAGCCAAGGTAAACGAGTTTTATTTGTGGGACAAGAACCTGCTTCAACATTATCCTTAATATTAGGTGCTAATATTGGCCCAGAACCAACAGAAATAGACTCGAATCTCAAAGCAGTCCATATTCAGGCAGCAAGTTTACTAGAAAGCGGTTGGAAAGAACTGAAAAAACTAGAAGCTGAATATATTCGTACACCCTTCTTTAAAAAGGTATATGGTCAAGAACTAGGAGTTTTACCAGGAGTAGAAGGAATTCTGACCATTAATGCTATGCAGGAATATAGTGCTAGTGGGAAATATGATTTGATTATTTACGATGGTACCGGAGATAAAGAGACACTAAGACTTTTGGGTTCGGCAGAAATTATGAGTTGGTATATTCGTCGCTTCCGTCAAGTTATTCTCGACTCAGACCTCTACAAAGCTATTTCTCCATTTGTTCAACCTGTTAGTAATGCTATTTTAAATGTTGACTGGACAGGGAATAATTTTTCTCAACCGACTGAAAAAATCAATGAACTTTTAGATAATGCTAAAGCTACTATAGCTGACCCCAACAGGGTGGCAGCATACTTGGTTACGACAAAGGATAAGGCAGCGATCGCCACAGCCAGATATTTATGGGGAAGTGCCCAACAAGTTAATCTCACTGTGGGGGGAGTAATTCTCAATCAAGCAGATAATGTAGATAATATTACTGCTGAATTTTCACCATTATCTGTAACTCCAGTTCCCCATGGTTCTAATGAAAATTGGCAACTTTTAATGGATGCTCTGCCAGATTTTAGCCAGGCAGTTAAAGCTCCCAAGCCTATTATCATAGATATTCAAAAAAGTCAAGTAAGTTTATTTTTACCTAGTTTTGATAAAAAACAAATTGGACTTATTCAAGATGGGCCAGAAGTAACTATAGAAGCAGGAGACCAGAGAAGAAATATTTTCCTTCCTCCACCCCTAAGTGGAAGACCTGTTCGTGGTGCAAAGTTCAAAGACGATTATTTGATTATTTCTTTTTAAAAGGAATGGGAAGTAGAGAAGAGGAAAAAAAGATTGATTTTGAGTTTGGTTAAAAGTTTATAGTAATTGTCAATAGATAACTACAGAACTAAAACCAAAATTTTGTAGGGACATTATAAAATCACAAAACATTTTTCAAGTGTATAAGAGGACTTATGCATAAATCGGGTTTATGAACTAAAATTTGCAATTATCTTGTATTAAATTAGGGTAATAAACCCGGTTGATTATTTGGGAAGCTTAAGTTCTATATAAATTACTTTTACTAATCAGAATAATCTCATTAAAAATGACTAATAAAGAACCAGAAAAATTGGAAAATAGCACTGCTAAAACTAGACAACTATTAGGAATGAAAGGTGCTGCAAGTGGAGAAACTAATATTTGGAAAATCCGTCTGCAATTAATGAAACCCATAACTTGGATTCCTTTGATATGGGGAGTAGTATGCGGTGCTGCATCTTCAGGAAATTATAGTTGGAATCTAGAAAATGTGTTGATGTCTGCTGCTTGTATGTTATTAGCAGGACCTTTGATGGCGGGTTATACACAAACTTTAAATGATTTTTATGACCGGGAAATAGACGCTATTAATGAACCTTATCGACCCATTCCTTCTGGTGCAATTTCTATTTCTCAAGTTGTGACTCAAATTGTTTTTTTGTTATTAGCAGGAGTTGGTTTATCATATCTCTTAGATTTGTCTGCTGGTCACGAATTTCCAATTCTTACTATGCTTTGTTTATTAGGTGCATTTTTAGCTTATATTTATTCGGCACCACCACTGAAGTTAAAACAAAATGGTTGGTTAGGAAATTATGCTTTAGGTTCTAGTTATATTGCTTTGCCTTGGTGGACTGGTCATGCTTTATTTGGAGAGCTAAATTTAACTATTGTAATTCTGACTTTGTTTTATAGTTTTGCTGGATTAGGAATTGCAGTAGTTAATGATTTTAAGAGTGTAGAGGGAGATGAAAAGTTAGGTTTAAAATCCTTACCTGTAATGTTTGGTATTGGTACTGCTGCTTGGATATGTGTATTAATGATTGATATTTTTCAAGCTGGAGTTGCAGTTTATTTAATTAGCATTAAAGAAAATTTGTATGCTGTTATTTTGTTGTTAATGGTAATTCCTCAGATTACTTTTCAGGATATGTATTTTCTCAGAAACCCTCTAGAAAATGATGTAAAATATCAAGCAAGCGCTCAACCTTTTTTAGTATTAGGTATGTTAATTACAGGTTTAGCTTTAGGTCATGCAGGAGTTTAGTATTGAAGAAATAAGGATGAAAACAATAGGAAAAATGCTAATAATTTAACTATAATAATCCTAAATAATTTGATAAAAAAAATAGTAAGATTTGGGTAACAAAAATCAAGGAAAAATATAAATTTGGAGGCCAAACCTAAGCAAAAATATTACAAGTTATTTAGGATTACTATAAAAAGTGATGATGACTTTTAAGAAAACAGATATTACTATAATTAATTATGAAAAAAAAGATGATATTAGCAGTAAACAATTAATTGGAATTTGCCCAAGTATTTGGGTCTAATTAGAAACTTTTTTATTTCTATAAAAATGTTTTTTTACTGTACGGATATGAGATATAAGTTGAAGTTTATTATAATCCCATATTGGCAATGTTCAGAGAGAAAATTTATAACTCTTCGATACTGTACAAGATAATATTGTTTACGGTAGGTTAAATGGCACAGATAAAGAAATTAATCATAGCAATAGAAACAATTAAATATCACAACTTCCGACTTGAATTTTACTGATGGTTATAACTCTATTATTGGGGAGCAAGGAGTGAAATTATCAGGAGAAAAAAGACAAAAAAAGCAATCGCCAGAGTTTTGTTAAAAAATTCCCAAATTGTCATTTTAGATGAAGCAACTTCAGCTTTAGACTCAGAGTCATAAAAATTAATTCAAAAGTCTGTAAAAAAACTTTTTTAAGGATATAATTAGTATAGTTATTACTCATCGGTCATCAATTATTTATCATATTGATTTAATTTTGGTTCAATAAATTGGTACAATAGTAGAAATGGAAACTCATGCATAATTAACTGTTTAAGAAGCTAGGTATGTTAATATTTATCAATTATAATTTTCTCAACTTTTTTTAGAATAGGAAAAGTCATACATTTATGTATAAAAAGTAATCTCTAGTAATCTTTGACAACTGATAACTTAACTGAAAAAAAAGGGTATAGTTAGGGTGTATCAACTACAATTTTCTCAACTTTTATAACCTAGCGATCTTCCCTGTCTATTGCTTTACCAAACCCTTGATAAAATCTGTTGTCAGACTCTAGCTTCAGTAGTAATATAGACCTCTAGGATAGTCGTGGCTATATACCTGCTACCGAATTTGATATAACTAATAAAGTTTTAATTCTCAGGAATTACGCAAACTAACCAATAAACCGGGTTTATTACCCTAATCATTGTTGTTCAAAGCTTGTTTTAAGTCAGTTCTGATAGTATAAAAACAAATATAAGAGAAAAAAGTGGCAAATAAAAAACAGAAAAATATTAAAGAGATATTCTCAGAAACAGAGGCTGATATAATCAGAAAATCTAAGTATATAGAGTCTCAGGTTAGGAACAATAAAAATAATTTTAATCCTGTATCAAATATGTTGAGTCAAAAATTTCAAGAGCCCTTACAAGCACCAAAATTTGATGGCAGAAAAAGCCAGAAAAAAAAAGTTAATCCTGTAGAAAAAAAGACAGGTAAAAAGGTTATAGACGTAAATATAAAAGGAATTTTATTGAGTTGGAAGCTATGGTTAGGGTTAGGTTTGATTGGAATTAGTAGTATTATGATTTACGGTGGGTGGATGTGGCGAAAATTAGAGCAAAGCTTACCAGAAGTTGCCGATATTTCCTCCTATAGAAGAGATGGTACTTTAACGATCAAAGCTACAGATGGTAAAATTATACAACAAACCGGACCTGCCACTCGAGAAAAAATTAAATTACAAGATATTCCTACTCCTTTAGTTCAAGCTTTTATTGCTGTTGAAGACAGACGTTTCTATGAACATAGAGGAGTTGATTATCCAGGAGTTATTCGAGCATTTATATTGAATATAATTGCTAGAGATATAGTTCAAGGGGGTAGCACTATTACCCAACAGTTAGCACGGATGGTTTTCCTTGATATGGAACAAAGTATTTGGCGTAAACTTCGGGAAGCAATGCTAGCTTGGAAAATAGAAAATGAGCTATCTAAAGAAGAAATTCTAGAATTATATCTAAATATAGTTTATCTGGGGTCAGGTACTTATGGAGTCGCTGATGCAGCCTGGGTTTACTTTAGCCAACCAGTTTTCGGACTAACTTTAGCACAAATGGCAACTTTGGCAGGTTTGCCTCCTGCACCCAGTCAATATTCACCTTTGGTTAACGAAGAAGCTGCTAAACGTCGGCGAAATCTAGTATTAAAAGAAATGCAAGCAGCAGGTTTGATTTCTGATGAGCGAACAAAAAGAGCGATCGCTCAACCAATGAAAATAAAACCTAGTGCGCCAAAACGTCTCATAGTTGAAGCTCCATATTTTGCTAACTATATTCAGAAAGAGTTACCGAAATATGTTTCCTCAGAAGTTATAATGGCAGGAGGTTTAACTGTAGAAACTACTCTGGATAGGCGTTGGCAAGAAATAGGGGAAAAAGTAATTCAAGAAGCTGTTGATATTGATGGTTATCGTCAAAGGTTTGACCAAGCAGCATTAGTCGCTATTGATGCTAATACTGGAGAGGTTAAGGCGTTAGTAGGAGGTCGAGATTTTGCTAAGAGTGAATTTAACCGAGCTATTCAAGCGCAACGTCAACCAGGTTCAACTTTTAAAAGTTTTGTCTATGCTGCTGCGGTTGCTGCTGGTATTCCTCCGACTAATGGTTATCGAGATTTACCGTTTACAGTAGATGGTTATAAACCCAAAAATTATGGTAAAAAGTATGGTGGTTGGCGATCAATGATTGATTCTTTGGCATATTCTGTAAATGTGGTGGCAGTGCAGGTGTTGATAGATGTAGGGTTTGAACCTGTGATTAATTTAGCTAAGGATATGGGGATTAAATCTGAGGTTAAGGCTACTTATTCTATGGCGTTGGGTAGTTGGGAGGTTAATTTATTAGAGCTGACAAATGCTTATGCGACTTTTGCTGCACAGGGTAAGTATATTCCAGCTCATGGAATCAAAAAAGTAATTAATCAAAACGGTAAGGTTATCTATGAGAGTAATTTTAAACCAAAGCAGGTGTTAGATAAGGATAGTGCGGCAATTGTTACCTGGATGTTGGAGAATGTGGTGAAATATGGTAGCGGAGCGAATGCTTATTTGTCTGATCGCCCTGTTGCAGGTAAAACTGGTACGACTGAAGAGGCCCGAGATTTGTGGTTTATTGGTTATATTCCCCAAGTGGCAACTGGAATTTGGTTTGGTAATGATGATAATAAACCTACTTGGGGTGTGAGTAGTACAGCAGCTTATAATTGGCAACAGTTTATGAGGAAAGTAGCTAAAGATATACCTGTGAAAAATTTTCCGAAAAAGCCCAGTTTTTACGATCGCAAACCTACTATTGAATCTAAACCAGTGACACCAAGATGGACTAGGTATGGGAATGTTGGGCCTGATGGTAGGGAGTTAGAAAAAAGAAATTATTATAGAGATTATTATGATGGGAGTTATTAGATTTTTTTGAGAAAAAGGATAACTGATGCTTTAATATTTATGCACTGATAAAATGCAAATTATTAATCCTGTCTTTTGTTCTAAGTATGATGGAAAAAAGGAAGGGCAAAAAGACAGGCGGTGCAAGTTTTGTTAACTTAGTTTTACTGAACCTAATTCAAAATGTATTTTTTAGCTGCTCACCTCACCCATAGTCTCATAAAAATGTTTCTTGGTGTATATTACAGCTATAAAAATTTATTTCTCTAATTTCCTTGTTGGAATAAATATACTTTTTTTTGTATTCATAAAAATCTCTTAAAAAGGAGTCATGAAAAATAGTTTTATACTATAAATAATGCGAGATTAAATATTTGTTTGAGTCTAGATAAAAGAGGATAGAATATTATTTGATTGGAGATTATTTTCTAATAAATCTCTTTATATTCTTGTCTTATATCGGATAATATTTTATTTTTCATTATTATCACTATAAATAAGGTAAACTTCATTTTTCATCAAAAACTTAAGTACTATATCCAGGTTTTAAATTTATATTCTTAATGTATTATATAAATTCTTAACTGGTTACGAAAATTTTTATTAATTTTCAGAGAAAATCTTTCTAACTCTAACTTTTAATTTCTGATACCAAATTCCCCAAGCATAAGAGAATATTTTTTAAATTTACCGCCGGGGAGATTATTTTTATATCCTAATTTTGTATAACTTAGTAAATACCACAAAAATATTTTAATTGAAATGGAATTTCTATATGTATGTATGAAAAAATATATGCCTCTATACCTCAAAAAACTAAATAGTTGTATGATTATAAATATTTTGTATAATAGTATTTATTTAGCAATGGTACAGTTTGCTCAGACAAAAATATTAAGGTAATTATAATTGTTTGACTGACAGGGTAGTCCCCTAAAAATGGTATATTATATTCCTTATTTCTTATTTTTACTTGATTATAATGTTTGATTGTATAATAGTTGGTTCCGGACCCGCAGGAGCAAGTGCTGCATATCATCTGGCAAAAAACGGACGTTCTGTATTAGTTTTAGAAAAAGAAACTTTACCTCGATATAAACCCTGTGGAGGTGGAGTTTCTCCTATTGTTCAAGAATGGTTTGATTTTGATTTTACACCAGCTATTTCTTTGAAAATTAACTCCATTTGTTATACTTGGAAAAAAGGCGATTTAGTAGAAGTAAAATTACAAAATAAACAACCTATTTGGATGGTACGTCGAGAAATTTTTGATTATTTTATTATTCAAAAAGCACAAAAACAAGGGGCTGAAATTAGAGATAAAACTAGAGTTATAGGTATAGAATTTAAGAACAATAATTGGCAAGTTTATACAGATAATCAGTCATTTACTTCTCCCTATTTAATTGCTGCTGATGGTGCTAAAGGTTCAATGGCAAAATGGTTAGGATTTAAAAATCGTAAACGTTTTGCTGGTGGAGCGATGGAAATAGAAATACCAGTTAAAAATCAGAAAATTGATAGTGCTTATTTTGAGTTTGGGATGTTAAATAATGGCTATGTTTGGAATTTTCCTAAAGCTGATGGATACTCAATAGGGGTTGGTACATTTTGGCGAAAACACGGTCAAAATTTTACGGCTTTATTAACAGAATATACGAGTATGTTTGAGGTAAATATTCAAAATGTTCAGAAGTTTGGTCATCCTTTATGTTTATGGAATGGAAATCAAAAATTACATACTCAAAATGCTGTTTTAGCAGGAGAAGCAGCTTGTATTGTTGACCCTTTTACTGCAGAAGGAATTCGCCCTTCTATATTTACAGGTGTTAAAGCAGCAAGAGCAATACATAATTCTCTAAATGGTGATTTATTTGCTTTAGAAAAGTATACTCAAATAATTAATGAAGAATGGGGGAAAGATATGGTATGGGCACAACGTTTAGCTCAAGGATTTTCTCGTTTTTCACATATTGGTTATCAAGTAGGTGTGAAGCGACCTCATGCTACTAATATTATGACAAAAATTATGTCAGGAGAATTGCGTTATTCTGATGTAGTGGGTTCTGCTTTACGACGACTTTGGCAAAGGTGAAAAGTAGGGAATACCATTTGATGTAAGTCAAAGTTTAACAGAAAAAGGATTAAATAATGGGGTAGCTAGTCATACAGAAAAAAATAGCGATCGCTTATTATCAAATACTAATATTAATATTATCAAACATTACGAAGATATTAGCTGTTTTCTAGAACCAGATTTAGTCATCAAAGAATTTATAGAGCTTTTAAGTAGTATTGACTATGGCAGCGATATTGAAAATTTACTTGAGTAAAAGACTGGGACAAAAAGTCATCCCTGAATGAATTTTTCTGGGGAAAATGCTCCGCGAACAGAATTGACTAATCTCCTCACCCTAAATAGGTATTACTATATTTAGGTAGTACTACATTATCGAAAAAAGCGATCGCTCCTCAACTCCAATATAAGCATTCAACAATTAACAGTCAGCTTCAGCGCTAAGGCTACCTTCGGAATGCTACGCGAACGAAATTCTGTGCAAACAGAACTTTGTAATTCTCCTTAGAGACTAACTAATTCCTCCTTCCAATATAACTAAGTTAATAACTCATATCTGATAGCTGACTGCTGAATACTTACAACCCAACTATCACCTGCTCAATTTTTCCGCACTATCCTGATTTTTATCATTAACAGGAGCAGTTTTACTATTTCCATTAACAGAACCATTACTAATCTCATCACCATCTGCCGAATATTGAGCATGCTTACGAAATAAACCGAACTGCAAACTCTTCCCCATCACCACATAAAACACAGGCACTACATACAAAGTCAAAACTGTAGACACCAACATTCCACCCATAACCGACATTCCGATGGAAACCCGACTAGCAGCGCCTGGACCAGAAGCAAACGCCAAGGGCATCACCCCAAAAATTGTCGAAAACCCTGTCATCAAAATCGGACGAAACCGCAACCGCGATGCCTCAATAGCAGCTTTAGTAATAGACATTCCCTCTGCCAATAACTGGTTAGCAAATTCCACAATCAAAATTGAATTCTTAGTTGCCAAACCAATTAACATAATTAACCCAATACGACTGTAAACATTCACCTCTAAATCTGCCAACCATAACGCCCCAAAAGCACCCAACAAAGATAAAGGTACCGACAATAAAATCACCAGCGGGTCGATATAACTCTCAAACTGAGCTGCCAAAGTTAAGAAAATAAAAATTAATGCCAACCCAAAAATATATGTCGTTGCCTGACCAGCATCTCGAAACTGGGATGACTCACCCTTTAGATCTATCCGCATATCAGCAGGTAAAACCCGATCCGCCAAATCGTATAATGCTTGCAATGCCTCACCCAAACTAACTCCTGGAGCCGGACTTCCTGTAATTGTTGCCGAACGAAAGCGGTTAAAATGATTAATCTCAGGAGGAGTTGTGCTTGTCTTCACAGTCACCACATTACTCAAAGGTATCATCACCCCTTGCTCAGTTCGCACATATAGATCCTCAATATCTTGGAGATTATTGCGAAACTCATCCTCAGCCCGCACAATTACATCATAGCGCTGGTTTCCTTGAGTAAAATTCGTAATATCTTCCCCACCCATCATAATTTGTAATGTCTGAGCAATATTCTCTACCGATATCCCTAAATTAGCAGCTTGGTAACGATTTATTTCTACTACGATCTCAGGCTTATTAATTTTTAAATCTGTGTCAACATTTTTTAGTTGGGGTAACTGTTGCGCCTCATTGTTAAATTCTTCAGATACTCGCACTAACTCTTCAAAATCATTTCCCTGCAAGACAAACTGTATGGAGCGACTAAGACCAGTACCAGGTAATGAACCAGGATTAATTGGAAATATTCGTGCATCTGTAATTGGTGCAAATGCTCTAAATAACTTTTTGACAACTTCTTGTTGTGCTTGCCCTGGTTTTGTCCGTTCTGACCAGGGTTTCAAGTTGGTGAAAGCAAAAGCTCGGTTAGCTTGAGCTGAACGACCGAACCCAGTAATACTGAAATAACCTTTCATTTCGGGAACTTGAGCAAGTTTATTTTCTACCTGACCCATGACATTGTCAGTATATTCAATGCTTACCCCTTCTGGTGCAGTTACAGAAACAAATACTCTTCCGCGATCTTCTGTGGGCAAAAATCCTTGGGGCAACTGTTGAAATAACCAAACTATTATCCAAAAAGATAGGATAAATCCTAAAATTACTAATGGTTTGATTCTCATCAACAGACGTAATGAGCGATCGTATATTACTGAAATGCGACTGAGAGCATAATCAAATAAATTAAGGGGAATGGTAAATAAACGAGAGATAAAATTTTTTTGTTCCTCTGGTTCTTGTTTTTTAAGAATTCGCCCTGACAATGATGGTGCTAATGTCAGAGCAACAAAGGTAGAAAACACTACTGACACTGCAATAGTTAGGGCAAATTCATTAAATATTCGCCCTGCACCCCCACCGGAAAATCCTACAGGTAGAAATACTGCAATTAAGACAATGGTTGTGGCAATGACAGCAAATACAACTTCCCCGACTCCTAATATTGCAGCTTCCATGGGAGTTTTGCCTTTCTGTTGAATATATCGAACAATATTTTCTAAGATCACAATAGCATCATCTACTACCAAACCTGTTGAAAGTGTTAGAGCAAATAAGGTGAGAGTGTTGATAGAAAATCCCATGAAAAACATTACCCCAAAGGCACCAATGAGGGAAATGGGAATGGTGATAGTAGGAATAATTGTTGCCCGCCAATTTTGCAAAAACATATAGATAACTAAGACAACTAAACAGATGGCGAATAGCAAACTTTTCCAGACTTCTTTGATGGCAACTTCCACAAATGTTGAGTAGTCAACGCTGACGTAGTATTCCATTCCATCGGGAAAATCTTTAGATAATTCTTTCATCCTAGTTTTGACACTTGTGGCAACTTCTATGATATTTGCTCCGGAAAGCTTACTAATTCCAATACCTATTGCTGGTTTACCATTATAGCGAGCAATTGTGCGATTACTTTCTGCTCCAATTTCTGCTCTACCAATATCTTTGAATCTTGTCAGAGAGGTGTCATCATTGCGTCTGATCACCAAGTTTTCGTAAGCTTCTGGTGTTTGTAGACGACCAATAGTGCGGATGGGGTATTCTGTAGATTTTCCTTCTATTCTACCACTGGGAATTTCTACGTTTTGTTGTCTAAGAGCTTGTTTGACATCTAAAGCAGTAATATTTCGAGCAGCCATTTTTTGGGGGTTTAACCATAGTCGCATGGCGTAACGACGTTCGCCTCCGATAAAAACACTACCCACTCCATTAACAGTTTCTAAGATATTTTTAATGAATTTATCGGCATAGTTGCTTAATTCTAATGATGAATATTTTTCCCCAGTTAGGGAAAGCCAAATAATTCTTTCTTCATCGCTACTTCGTTTAGAAACTACTGGTGCATCAACTTCATTGGGAAGTCTTCTCATGGCACGGGAGACACGACTACGAACATCTTGAGCTGCTGCTTCTATATTGCGACTCAGTTGAAATTCAACGTTTATGGAACTTGAACCTTCCCTGGTGCTAGATGTCAGAGTTTTCACACCTTCAACACCATTAATTTCTGCTTCCAGAATTTCTGTTACTTCTGTTTCTACTACTTCTGGGCTAGCTCCTGGGTAGTTGGTTCGTACACTGACTACTGGGGTATCAATGCTAGGAAATTCTTGTACTGGTAGACTGATATAACCGACTAATCCAATTAGGATAATTAGTAGGGAACACACTGAGGCAAATACTGGTCTTTTGATGAAAAAATTTGTAAACATTTATTTTGAAGTCAAAAGTCAAAATTCAAAGGTTCAAAGTTCAAAGTTAGAGTTTAGAAGTTAAAAGTCAAAAGCTCAAAGTCAAAATTTCAAAGTTATAGTTTCAAAGTTATAGTTTAGAAGTTTAAAATCAAATTTTCAAATTTCAAAGTCAAAATTTCAAAAAATTAAAGTCCAAACTTCAAGTTTCAAAGTAAAAGTTAGAATTTCACAGTTAAAAGTAATACTTTAACTGTGATTAAATTGGTAAATCTTATAAAATATTAAACAATAAATAGCTATAGTATTTAATAGGAATTAGGCAAATAAACCTGGTTTATGTGATAAATCATTGTTTTAAGAATAGACATCTAAGAAAAAAATAGGGTTTCTAGTTTTATTTGCGTAAGTCTAATTTAATTGATAAAAATTCAAAGCATTGAAACTGTGGATAGAATAGACATCTCCAATAATAAAAAATCAACAGGACGAACAGAAAGCCCCTACTAGATATGGCGGTTTTATGTAAGTCATGATAAGATTAATTATCCCACAGAAATTATCAAAATTTCCCCCTATACGGAAATTTAAAAAATAAAAAAATATAATGTCCCTACTAATGCCTAATCTCTATCCTAAAATATAGCGCTTAATCGTGATTATGAGGCATAATAATAGTACTTACAGTAGATTCCCAACTAAATATAGTATAATTAATGAGATAAATATTTTTGGCTTGTTTCCTATCCCAATTCCTTAAAACTATCAATATATTTATCTCATAACTTAGGAAACCATTCTATTTGTAGATAGCTAGCAACTTTTAATGATTAATGAAAGAAATAATCAAGAATATTTTAACTAACCTAGGCCAGGTCAAACTACCTGCTCCATCATATTTTGATTCTCTTGAAACTTACACAGTTAAGAAAGTCTCAGATGCCGACACCTTTAATGTTGTTGCTAATGGTTCTGAGGTAGAAATGACTGTCCGTTTTGTTTATATTGATACCCCAGAAACTCCTAAAGGATGGGGAGATTCACAGGTGGAAAAAATGAATCATAAAAATAAAAATCCAATATATCGTAGTCAATTTGAATGGGGAGAAAAAGGTAAAGATAGGCTCCAAGAATTAGTTCAAAAAAGTGATAATCAAGTCAAAGTTAAAGTTACTGGAGAAGAAAACCGACCAGGGCGATCGCCACGTTGTTTTGGTGAAGTTTATTTACTAGATGGTACTTTTGTACAGCACATCTTAGTAAAAGAAGGTTTAGCTCGAGTTTATTATGATTATATTAGCGAATGCCCTAGAGAAATTGCAATTATGTTATTCTTGGCAGAAGCTGATGCTGAGATAAACCAACGGGGAATATGGCAAGAACTTCAATCAGAATTTATGGCTCCTTGGGTATTCCGTTCCCTCAAGAAAAAACAAAAGAATTTTCTTAAAGATATAGGTAAAGAATTGAAAGCAGGTTCAATTAATGAAGCTGAGTTTGAAGCCAAGTTTGAGCTTAAACTGCAGCAGCAAAATCAGATTTTATCAATTCTTCAAAAAGAGTTGATAAGTGGTCTAATTACCCAAGCCAAGTTTGAGGATAAGTGCAAAGAAGAATTGAATCATTTATTTGCATAATCAATTATATTTTCACATCAAAATATAATCTTTTTTATAATTTTATTGGTTATAATTTCTGAATTTATATTGATAGTTTTTAGCAATTTTATCTGATATCTAAAAAATGCTCACTTTAGTTAACCATAACTATTATTTATTTTATTTTCATCAATAATTTAAGTAAGCTGTGAAACATTAAATTTTAAGATATAAAAATAGTAATTTTGACTATCAAAATTAATTTTCAGAGGATTGCCACTATTTTTTTAATCAAAGAATATGTAATTTAAATACCTAGAAACTTGGGTTTCTATTAAAAAGATTGTTTTGACCAAGTATTAAGTGAAAATAGATAAAGTCTTAAAAACCCTTTCATAAATCCTCTGTAGAATTTTGATAAATTCTAGTAGTACCATAAATTTTGATTATGATCTAATCATAATAAGCAAGTATACAAAATTAATTATGCATCTATACAAGCTGAATTTTTACCAGGCAAAAAAAATCTAAGAATTAGAAGATGCCAATAAATTAGTAATTATACTTATTCCTGTAGAGACTAATATTTCATCCCTACAGGAACAACTAATCAAACTTAAAAAATCACCCAGCTATTAACCCCGGAGTTTCTCTGACCAAACACGAGTCGGCAAACCCCAAACATAAATAAATCCTTCCGCCGCTTTATGGTCAAACTCATCCTCCGCACCATAAGTCGCTAAGTCAAAACTATACAAAGAATTATCAGACTTACGACCAACAACCATTGCATTACCCTTAAACAACTTGACCCGCACAACACCAGTCACCCTTTCCTGGGTCTGCTGAATAAAAGCATCCAATGCACCCTTCAACGGACTAAACCACAAACCGTTATAAACCAACTGACTATAAGTCTCCTCAATACCCCGCTTATAACGAGTTACATCAGCAGTTAAAGTCAAACTCTCTAAATCTCGGTGTCCTTGAATTAACACCCACATTGCCGGAGACTCATAAATTTCTCTCGACTTAATCCCCACCAGACGGTTTTCAATCATGTCAATTCGACCAATGCCATGGTTTCCTGCTATCTGATTAAGTTTAGTTATCAACTCAATACCACCCATTTCTTGACCATTAAGACTAACAGGAATACCCCGCTCAAAACCAATCTCTATATATTCTGGTTCGTTGGGAGTGTCAGCGATCGCCTTAGTCATCCCATAAACTTCTTCTGGGGGCTCCACCCAAGGATCTTCCAACTCACCAGCTTCGATCGCCATCCCCAATAAATTCTTATCTATACTATAAGGGGAAGATTTTTTCACAGGAGCCGGAATGCCATACTCTTCACCATAAGCAATAGTCTCCTCCCGACTCATTCCCCACTCCCGCGCAGGTGCAAGAATCTTAATTTGAGGATTTAGTGCGGCAATAGCAACATCAAACCTTACCTGGTCATTACCTTTTCCTGTACAACCGTGGGCAATAGCATCAGCACCATATTTTTCTGCTGCCTCTACTAATATTTTGGCAATTAGAGGTCGAGCTAATGCTGTTGCTAGAGGGTAGCGATTTTCATATAGAGCATTTGCTTGAATAGCAGGAAAAGCATATTCTTTAATTAGAGGTTCAATAACATCTATGACTAGAGATTCTACTGCCCCAGAATCTAATGCTTTTTTCCGAACTCCTTCTAATTCATCTCCTTGACCTAAATCTGCTGCTAGGGTAATTACTTCTTTTACTCCCCATTCATTTTTCAGATAAGGGATACAAACAGAAGTATCTACTCCTCCAGAATAAGCTAGCACAACTTTAGTAGCACGACTCATATTTTTATTCAAAAATTAACAACTGAGTTATTATTATTAAACTAAATCTGTAGCTTTATTGTTAATTAAAGTATAAACTTTTTTTATGCCAATAAAAACCTTAATAAATTTTACTACAGAGGAAACCAAAAGTTTTTCTGATTTTTGAATTTTAAATTTGAGTTTTACTTAGACTCTACAGTAAACGTCCAAAGTTATAATTTTGAATAATGCCACCTTCCCCAACAATAGTCCCTATCAGAACCAACACAGGAGGGCAAAAACACAATCTTTTTAGGCAATCTTTTTAAGTGACAGATATAGCGCGACGGAACTTTTAGGAGTCCTCGGATTAAAAATCTTAGGAAAAGTCAAAACTAAAAAGGATTTGGTAGTTCTGCTCCCGTAATGGTTTTTGAGTAAGTAAAATGGGGGTTGGGTTGGGGGGAATTGAGTAGTTGGGGTGATGGGGAGTATTCTTCCCACTATTTGACCCTAATCTTGAGTTTTTCCTTTTCTCCAAGAAGAAAAATTATCATGCCCCCATATCTTTCACTAAGGACCCAAGTAGCACTACCCAGGATTGAATATAAATAACTGACTCTATGTTTTTTAGTATAATTATTCCCACTTATAATCGCCTGGGAATTTTAGAAAAATGCCTCCGTGCCCTAGAAAGTCAAACTTATGAACAACACATAACCGAATATGAAGTAATAGTTGTCGATGATGGTTCAACAGATGATACTATCCCCTGGCTAAAAGCTAATGCCACAGAATTTCCCCATCTCCAACTTTGGCCTCAGTCTCACCAGGGACCAGCAGCAGCCAGAAATTTAGGAGTTGAAGTAGCTAGGGGAAATTTTATTATTTTTATAGATAGTGACTTAGTAGTAACAGATAATTTTCTTCAGGCCCATGCAAATACTTTAATTAAATATGGCAAAAAATCAAACTGTATCTTTACTTATGGCAGAGTAATTAATACTTGTAATTTTGATTTTCCCACTTTAGAACCATTAAAATTGACGGATTTTTCAGCAGCTTTTTTTGCTACTGGAAATGTAGCGATCGCTCGTCATTGGTTAATTGAAGCTGGATTATTTGATACTAATTTTAACCAGTATGGTTGGGAAGATTTAGAGTTAGGAATTAGGCTAAAAAAATTAGGTTTAAAATTAATTAAATGCTCAGAAGCAGTAGGTTATCATTGGCATCCACCCTTTTCTTTGGAGCAATTGCCAAGAATGATTGACAGAGAAATTCAAAGAGGAAAAATGGGAGTTTTATTCTATCAAAAACATCCTATATTGGAAGTAAAAATTATGATTCAAATGACTTATTTCCACAAGTTATTATGGGGAGTTTTATCACTAGGTGGGAGACTAAATGAGAAAACAATGGCAGTTTTTTTACAATGGTTAATTGACCGAGGTAAATCACAATTGGCTTTAGAAATTTCTCGAATATTTTTGAATTGGTATAATGTCAAAGCTGTTTATAGTGCTTATGCTAATATTGATGGTTTTAGGAAGTAATACTATTTCTCAATCATTTATGCTATTCTACTGAGAAGTTGTATAATATAATCCCATCTCAATAGCAATTATTTTCTCCTAGCTTATCAAACCCAAACCAAGACTCTATCTACTTGAAAACTAGAAATTCTAATGCTAGAGTTGAAGTTTTTGCTAAAGTTTTTTCTTCCTCTAATTATTGAATATTTTATATAGACTCGAAAATATGATAATTTCCGAAAAATAATTTGGAAGTATTTTGAGATAACTATAGCTAATTTAGCCATACTATAATGATTGAACCTGATTTTCCTCATATTATACTTACCTTCGAATATAAAGGTTGGAAGGTCGAAATTGACCAAGGTGAAATGAATGGATCTGCTACTTATGCAGTTTGGGCTAATTATAATAATGGTTGTGTTGTAGCAGTACCATTAGCTTCCTCTCGACAAGAGGCAGTTAGACGTGCCAAGCAATGGATTAATACTCGAAATAAGAAAAATAAAACTTAGGTTCTCATCTATATTTTTTGAGGGTTAGTTGTACTTAATTTTTTTGTTTTCTTTTGCCTATTCTTTATTAAGTTACTTCTTAAAACCTATCACTTTGTATTTTTCTCTTTAATCCTATAAGTAAAATTTAATATAACACTAATTCCCCAAAATAATATAATGTAAGACTTAAGAGCAAAACTTCAGCTATTAAGTAATAAGTCAGTAATAGCAATTTTTTTAACCTATACTGTGCCAAGAATATAATTATTACTTATTAATCACGAATATGACTCCCTAATAAATTAAATAATTCAGTCATTATTTATGATCTTTCCCTTCCTTAAAAGCCATAATTATAATTATTTTGTAATCAGCTATCCATTGACCTTTATAAAATAGATTAGGACGCAATCTATTTTTAATATCATCAATAATAACATTTTGCTTTTTTTCAGGAATCCCTTGAAAAAAACAAATCGCAAAAATATTAATCCAATTACGTAGACCATTTTCTCCATTTTTAAGTTTAGTTAGTATTCCTAATAAAGTTGCAAAAATCGATAAAAGAACTTTTAATTTTAAAAGTTTAGCAGATTCTCTAATACTAGGAAAATATCAAGAATTAAGCTTTTTATTACTGCCATAACCAGCAGCATCTAAAGCTTCATAAATACCACTAATAATTGTTTTAACATTACCTTTTATTCCAAATTATGTGAGGAAACGACCTCCTAGTTTTATTAGACGCCAAATATCAGTGAGAAATTTTTCTTGTTGTTAAATATAATCAAATGTTATATTAGAAAATACTGCATCGAATGTTTATTTAAACTCAATGTTAATTTCATCTCCTACTAAAAACTCAGTATCTGGATAACAACAGTTTGCTCGCTAAACTATAGTAAAAGTATTATCAATTCCTATAATATTTGCTCCTTTTGTAGTAATTTTATAATTTAGATTACCTGTACCACAAACAAGAGCAAGAATTTTTTATCCATTTTGCATACTTAGCAGCTCTAATAAATTTCTTGCCAAGCTAGAAACAAAATAATATTTACTCTCATAAAGTTCTACATCACACTGATTGAAAGAGACATTTGATAAGTTTTTATTTGTATAATTTTTCATAGTAGTATCACTAGTAATTTATTCTATGAATTATATTTACTTGTCAGCTAAAATTTGTTAATTCAAAAGTAAAAAATAAGGTTTAAATGATGAATATAGATAATTTATATAATCTATAACCTAGTGTTTTCAAAGTTCAAAAACTATAAATAAACTCTGAAACCATTGCCTATTGAACCGATGACTTCAAACCCCTATACCCAAAACTATAAGATGGGTAAAAAAAATTAACTTTAGAGTATTACTATATTGAGTTCAACAAGTAGTAATAGTTAGAATATTTTAAAAAAAAATACTTTAGTAATAAGTGGAAATAATATTAATAGAGAAAAGTGATTTTAGCTATAGCCAAACATTTGGAATTAGCATAATGAGTAGAATATTCTCAGCAAAACTTTTCAGTTAAGACCCTATTTAATGTCGATTAGTATACTAACTTTTTTTTAGCTTTGTAATATTGACTTGACAAAAAAAATTTAGCGATCGCTCATTAGGATAACTTGATTTTTCAAAATATCCAAAATAGACTGTATATAATCGCATCAAAGCATAACTATATACCCAGCATTTATCTACAAAAAAATTTCGAGATAATACTAGGTACTTTCTGAATTTTTAAGTAAAAATACTGTGATAATATAATAATAGTCATAAATCATAACTATTAAGTTAATAATATCTCTAAAAACCTCTAGTTTATAGATTAAATTTATTAAGAATAAATAGTTATTTTATGATAATAAATACAATAATCATCTTGATTTTAATACATAAGTTATTTAGGAGTAGGCCTTATGGCAAATAACATGGTAGCTTCAGATCTGTGGATAAGTGAGCATATTACACCTTGGGATATTTATGTTCATGGCCTTACTAAGGTACTTGCCTACAAAAAAACTGCTTACCAAGAAATGTACATTGTAGAAACAGGTATTTATGGTAAGGCACTGGTTCTTGATGGTAAATGGCAGTCTTGTACAGGGGATGAATTTCTATACCATGAACCCCTGGTCCATCCTGCTATGATTTGTCATGGGTCTCCTCGCAAAGTTCTTGTTCTTGGTGGTGGTGAGGGAGCTACTATTCGGGAAGTTTTCCGTTGGCAAAGTGTAGAAAAAGTGGCCATGGTTGATATTGATGGAGAAGTAGTAGAAGCTTGTCGTCAATATTTGCCGGAGATGCATGCCAATGCTTTTGATGACCCCCGCCTCCAGTTGGTCATTGGTGATGCTTTAAAATTTTTGGAGACTTTTGGTGAGAGTTGGGATGTGGTCATTTCTGATCTTTCTGATCCTATTGAAGAGGGACCATCATTTCAATTGTTTACAAAGGAATATTTTGAAAAAATTCTGCGGGTACTTACCCCGGGAGGATTTTTTGTTGTACAGGCAGGTCCTGTTTCCCCTGGTGAAATGAAACTTCATGCTCGAATTGTTAATACAATGAAGGCTGTATTTCCTTTTGTTCAATCTTATAATAGTAATATTCCTACTTATGGTCGACCTTGGGGTTTTGCACTGGGCTCTAGGAAAATGGTTAATAGTCGCCCTGAACCAGAAATGATTGATAAACTTCTGAAAGAAAAAACTATTGGTGGGTTCCGGATGTTGGATGGCACTACCTTATTAGGAATGTTGCAGGTACCACTACATCTGCGAGAAGCGATCGCTACTGAAACAAAAATCTATACTTTAGCAGAACCTCCAAAATTTGGTCGTCCTGCATAGTAATTATTTTTGAGTAAAACTGGAATTATATGATGGGAAGGCAGAGAGTATAGGTGCCTGATATGGGACTTTTTTTGAGAGTTTTTACCCTAAGCATAAACAAACAATATTAAGATCCTATCTTTTTCACTATTTCTATACTACTACTACAAAATTTTTCGGTAAAAGTTCCACTAACAACTGAAGTTATATTAAAAGGGAACAAGGTTAGGAGGTTGACTATACAATACTAACTTGTATAAGCCAATACGGTTCAGATAAAATCAAGGTTCGATCAGATTCTGAATTCCTATAATTCCTAATATTTCTGGCTAGCGCCATATACTCCAAAAAATTTTAATTGTATTTCAGAGTAACTCAAATGTCTATACTAAGAATTCTAGCTGCTATTTTTTTACCACCATTAGGAGTTTTTTTAACTGTTGGTCTAGGTGGTGCTTTTTGGATTAATCTTCTCCTAACTATTTTTGGCTTTTATATTGCTGGCATTGTTCATGCTATTTGGGTAATTGCCAAGCATGATAATTAAATTAAGTAATTAAGATAGGGGTGAGTTTTGTCTGATGTCTGATGAATTTTTAACTCAAAATAATCATTAACTCATCTCTATTAATATGAGTAATATGAATGAATTTTGATTATTAATTGTTCACAGTAAATCATTCAATTACTGACAAGTAATAAATTATCAAAAATCTCTAAACAGATGTGAAAATGATTACCATTGAAATAGATGTTTAGAGTTTTTTAAAAACATTAACTTTTTTCATTCAAAGCTATACTAAATTAAATCTTAGTAATCTAACTAATCAACAGTAACGTCACAATAATTATGAAAGGTATAATACTTGCAGTTTCTATTCAAAAAGGTAATGGAATAATCTCTGGTGATGATGGCAAAAGATATAGGTTTCTGCTATCAAGTTGGTACGCTGAACAGAACCCAAAACAAGGCTTAAGGGTTGATTTTGATACAACTCCTGAAGGAGAAGCATTGGATATATACCAAGATATTTCTGATATTTCTGCATCACCATCAAGTCAACTGAATCCTAAAAATCGTGGAATTGCTGCAATTTTAGCTTTTTTTCTAGGTGCGTTTGGAGCACATAAATTTTATCTTGGCTACTCTCAAGCAGCAATAATAATGCTTATTGTTTCTTTAGTTGGTTCATTTCTTGTAATTCCAACCTTAGTTATGAGTATTATTGCATTTATTGAGTTTATTACCTATTTAACTAAGTCTGACCAAGAGTTTTACGATACTTACTTGAAAAATAAAAAAGCATGGTTTTAAGTTATGTATAAAAAAATTTTAGTTTGATTTCAAACAGTTTTTAAAATTAAATTGAAATATTTTTTTTGTAGTATATACCAAAAACTTCATGATTTTGATACCGTAAATAGCAGTGTTATAAATATATTTTTTTTGAAGATCACTTTTATTAACTATTTAAGATAATTAATTATCGTAAAGTATTCAAAAAAAGATAAATCTGGACTGTATTAATCATTAAAAATCATACTTTATTTGAGGGTTATTTTTTACTCTTCTATTTTTTCTTGGCTCCTTGACACTTGACACCTAATACAAACAAATTTGATTAAAAGGAGAAGTCTAAAATTTTCTCGCTTAATGAGCTTCGATATAATTAGATTAAGCTATCAATGCTCTATCATTTTTATCATTTGCAAATTTATTTTTTTCCCTATTATCTTTATTATCTTTATCACAATCTTTTTTTTTAATATCACTAGATAAATTTGATTAGATGTATTTAACAGGGCATGATATTATAAAATATATAAAGTAGTTTTTTACGAAAAGCCAGATAACAATGCAAATAGTTAATTCTCAAATATCTATAGAAAAAACTAGCCACTCTCGGATTAAAGAACAGGATATTAATAATACTCCCTTTGGTAAAGTATTTAGCGATCATATGTTGGTTGCTACCTATGCAAATAATAGTTGGCAAGAGGTAAAAATTACTCCCTATGGTAATATTTCTATTCGTCCTTCTCTCTCTGTACTTCATTATGGTCAGGCAGTTTTTGAAGGTTTAAAAGCTTATAAAAATTATCAGGGAAAACCTGTATTATTTCGGTTAGAAGCTAATTATAAAAGAATAAATAATTCAGCTTTTAGATTATGTATGCCATCCATTCCTAAAGAAATTTTTATAGATGGTTTAAAGGAATTAATTAGACTAGATACTGATTGGATTCCTACTAAATCAGATAGCGCATTATATATTCGACCTATTTATTTCGCTACAGATGAATCTGTCGGTCTCAAGCCTGCAAATAGTTATAAGTTTATTATTTTGTCTTCCCCTACAGGTACATTTTATTCGGCACCAGTTAAGTTAATTGTTACAGATAAATATGTCCGAGCTTCTGAAGGTGGAACTGGTGCAGCTAAATGTGCTGGGAATTATGCTGGTAGTTTTTTAGCAGATAAAGAAGCTAAAGAACAAGGTTATGATAATGTTTTATGGTTGGATGGAAAGGAAAAAAAATATATTGAAGAATGTGGTACGATGAATGTTGCTTTTGTAATTAATGATGTTTTGATTACTCCTAAGTTGACAGGAAGTATATTAGGGGGAATTACTCGAGATAGTGCATTAACTTTATTTAGAGATATGGGTGTTAAAGTTGAGGAAAGATTAATCTCTATTGATGAGGTTGCAAAGGCTTATGAAGCAGGAAATATTTCTGAGGCTTTTGGTATGGGTACTGCTGCTACAATTGCTCATATTTCTGTTATTAACTATCAAGGTAAAGATATGATTTTACCTCCTGTTGATGAACGAAAATATGCTTCTCAAGTTTTGCAAAAATTAGAAGATATTAAAACTGGTAAAGTCACTGACCCCTATGGTTGGATTTGTCAACTTTAAATACTTGAATATTATATTAGTCTTGGGATGATATAGCTGAATTTAGAATTCATAATTTAGAAGCTATAAGCCAAAATTAAAGAACATAAATTACTCAATAAAAATAATTTTTATAGAATATAAATATAGCAATTATCGGCTGTAATTTTGTCTAAAATATTGCTGTTTTTTGGTAGCCTAGACTAGGAAATTACTAATATTTTTGAAGTTTATTTCTAGTTATTAAGTTGTTTAAAAAAATGTTTTTATATAATTTTTATATAATTTTTATATGGCTAAAATTTATCCTAATTTAGGATGAGATAAAATATTAAAAGTATGACTAGGTATTTTTGATAGTTTAACAGGAGAGTTGAAAATTTGTTGAGAAATGACAACAAACATTAGGATGAGAAGGGGGATTGAGCCTTGACTTCTAAAAATATGACAACTTAACTAACTGATTCCTAACTACTACCAAAATATTACATTACAAATTTTGTGAGTCTAATAAACTACATAGCCAGGCTTAATAATTAATAGTGTTAGGGTGTAACTTGAAAATTAAACTAAGTCAAAAAAACCTAATTTAAAATCAATGATAAAACAAGGTAGTTTCAAATCAATACTATCTATCTTTAAAGCTCCTGCCGGATTAATAGCTGGTTCAACCTATCATTTTCGTGCTTTAATAATATTTGTAAAAAATCCTAGATTAATCAATTACATAATTGCTCCGATTTTTATTAATATTGTTGTCGGTATTTTTCTGTATATTAGTCTGCTATTACCTGGAATAAGTTTAATTAATACTATCTTTAATAATTTATCTTTGCAGTTTGATAGCCTGATTTATCAATTACCAACTTGGTTAAAATTCTTGAGTTATTTGGATAATGCTTTAGGTTTGCTCTTTAAGCTCATTCTATTTACAATATTTTTGCTAATTATTGGATTTTTGTTAGTACAATTTGGAGTTATTCTTGGTTCTCCTTTTTATGGTCAACTTTCTGAACAATTAGAAAAAACTCGAACTGGTACATTACCTGAAGCTTCTTCTGGTTTACTATCTATTATTAGGGATATTTACCGAGCTATACTTTTTGAGCTCAAAAAAGTGGCATTATTATTAGCAATAGGCTTGCCGATGTTGTTGCTCAATTTTTTTCCTGGAGGCTCTTTAATAGCAACTATTGGCGGCATCGCTTTAACAACTTCTATTGTTTGTCTTGACTTTTTTGATGGACCTTTGGAGAGAAGAAAATTAAAATTTCGAGAGAAGTTAAAAGTTGTATATCGTAGCTTACCAGCAAGTGCCACTTTTGGGTTAATTTGTCAAGTTTTAATTACTATTCCTATAGTTAATTTTTTGGCTATTCCTATATGTGTAGTGGCAGGGACTTTATTTTGTTGCGATCGCGTACTACCAAAGTTATTACCAAATAACCAAACTTAAAGAGGGTTTTTAGGTACTATACATTAAATATTAGGGCTTTGATGGCTGATTACAGTAGCAGCCTTTAGGAGAGAGCATGGGTAAGAAAAATGTCAACCTACTATTGAGGTTCGGCTCGGTAGAAATCTCCGCACCTTTACTTTGGGAAGAATATCAAGTTTTTCATTTACAATACCCTCTTATGAGATTTATTGAAAAACCTCTCTCTCAAAGTGGGAAAACATAAAACATAAAGTATAATATTATTGTCTATTGTCGTGGGTGGGCAATCTGAGACATTAAGCAGACGTACAGGGAAGCATAACTTACCTTTATCCACTCCTTCGATGGGGGCAAAAAGGATGGGTGCAGCATTCAATAAAACGTCAACCCACTGAAGAGCTTAGGCTCAGTATGTATCTCCGCGCCTTTATGTCGCTGAGGATCTCAAAATTTTAACAACAATGTAATTTTTTCTATATAAATGGGGATATCTTTGAAAATTATGCTTAACACAATTGCAACTCAGATTAGAAAGTGGTTCTCAGCACCAGAGGTGAGTGCTCACTGTGATGGTCCTTGCGGTGTTTATGACCCTGCTTCTGCTCGCATTTACGCTGAAGCTGTATTATCTATGACTAAGAAAATTCTAGATCTTGACCCAAAAGCTGGAGATCATAAGACTGCTAATACCCTTTCTCGCTATATTGCAATTAAGGAAGAGCAAGCTCAGAAGACTAAGGAAGATTTGCTTATTCTCTGGACTGATTATTTTAAGCCTGTACATTTAGAAAAGTATCCAGACCTCCACGATACTTTTTGGAAGGCTGCTAAGTTATGCTCTGCTTGTAAGGTAGAAGTTAGTTTGGAGCATGCTACTGAGTTACTAGCTGCTGTGGAGAAAATTCACAATATGTTCTGGGCTACTAAGGAGCGGGATGTGACTTGGTACAAGGCTAGCTAATTTTTTTTGTTTGAGGTGGTAGGTACAAGGTTGATACAAACAATTGATAATAAAGAATTATTGCTTTGGTTATTAAGGTTGCGCCAACGGTTTTGTGTCACAGGATTTTCTATGTTTCCTATACTTAAACCTGGAGATGAGGTTCTTGTAGATACAAAAGCCTACCACCACTGTGCTCCAGAAATAGGGGATATGGTTGTGGCTGAACACCCTCATCGTCAAGAGTTAAAAATAATTAAGTGGGTTGCTTTTGTTGATGAAAAAGGTGACTGTTTTTTGGTCGGAGAAAATAAGGAAGAAAGTACCGATAGTCGTTCTTTTGGTTTGGTAAATCGAAAACGAATAATTGGTAAGGTAAAGAGCAAGTTTCCAACATAGTTTAACACATTAGGTTTGAAGGATATTGGTTGAATAAAAAATCATGTTTGCATTTAAATAACTCTTACTAATTTCAGTATATCAATTTTTTTTTAATTGGAGCTTCGCAAAATGATAGTAGCTGCTATCTGTTGTCTTGCTATTTCAGGCACAAAGCGATCATCAGAGAACTAGTTATATAAGACTTATGATTTTTTTCTAGTTGAATAAAAAATCATACAAAAGGGCGAGTTTGTACCACTAACTATAGTATATCAAATTTTTTTTGAGAATGGCTGGTGGAAATAATAATGCTTTTTAGAGCTCCGTAAAATGATAGCGATCGCTATCTGTTGTCTTGCTATTTCAGGCACAAAGCGATCATCAGAGAACTAGTCATATAAGACTTATGATTTTTTTCTAGTTGAATAAAAAATCATACAAAAGGGCGAGTTTGTACCACTAACTATAGTATATCAAATTTTTTTTGAGAATGGCTGGTGGAAATAATAATGCTTTTTTAGAGCTTTGTAAAATGAGAGCGATCGCTATCTGTTGTCTTGCTATTTCAGGCTCAAAGCGTCGAGACTTATGATTTTTTCTAGTTGAATAAAAAATCATACAAAAGGGCGAGTTTGTACCACTAACTATAGTATATCAAATTTTTTTTGAGAATGGCTGGTGGAAATAATAATGCTTTTTTAGAGCTTTGTAAAATGAGAGCGATCGCTATCTGTTGTCTTGCTATTTCAGGCACAAAGCGATCATCAGAGAACTAGTCATATAAGACTTATGATTTTTTTTTAGTTGAATAAAAAATCATACAAAAGGGCGAGTTTGTACCACTAACTATAGTATATCAAATTTTTTTTGAGAATGGCTGGTGGAAATAATAATGCTTTTTTAGAGCTTTGTAAAATGAGAGCGATCGCTATCTGTTGTCTTGCTATTTCAGGCACAAAGCGATCATCAGAGAACTAGTTATATAAGACTTATGATTTTTTTCTAGTTGAATAAAAAATCATACAAAAGGGCGAGCTTGTACCACTGTACCACTAACTATAGTATATCAAATTTTTTTTGAGAATGGCTGGTGAAAATAATAATGTTTTTTTAGAGCTCCGTAAAATGCCAACTAGTTGTTTAGTGGGGGGGGAGGAATGGCTTACATAGGAGATTGAGGCATTTTATTTAATGATCTAGGGGAGTCGTGCCTCACTTTTGGTAGATATTTGAGGAGCCTTAATTCATAATTGTAGCGATCGTAACTAGTGATTTTTTGATTGAATAAAAAATCATATTTAAATTGTTGGTATTGAGTAGAGCGATCGCTGTGCTGACTTTATGGTTAGTTTATAGTTAGTTTTTCTTGGCAAGTACCTTTGCTGAAAAATCAGGATGTAGGGACTTGGTATATAATCTTCCTCAAAGGTTTATGTCAAAACCAAGTTAACTCCTCTGGGAGAAATTCCCACACTTCCTTAAAAAGGAAAGTGCTACGGGAAAGCCAGTAGTTAGTTTTGTGGTTCATTCTTGCTTTCGCTCTTTTTTTTGAGCATTGAGACAGTAAAAACACCACAGGACGCAATAAAGTAAGACTCAATAACTATTCCTTTGGGATTTATCAAAATGATTTTCATTATTTAAGTGAAGCATTTAAAAGATATAAAGAAGGAAGCAATATATCAATTTCCATCAATTAAGAACTAATGACTATAGCTATAGATTTCGGAACAAGTAATACTGTTATTTCTCGTTGGAATCAAACAACTAAACAACCAGAAATTGTCAAGTTACCAAATATCTCAATTCTTTCTGTGGAAAATCCGCCTTTAATTCCTAGCTTAGTCTATGTGGAAAATGTTGCTGAAAAAAAAGTAGTAGTAGGTCAACAGGTTAGAGATAAAGGTTACGATGTTAATACGGAATCTAGATTTTTTCGTAATTTCAAACGGGGTATTGGTGCAAATGTTCAAGGATTTTTGCCGGAACTTGACGGTCAAATTGTTTCTTTTGAACAGGTAGGGAAATTGTTTTTAGAAGAAGTTGTAGCAGGTCTTCAGAAAGTGCCTTTGCCAGTAGAGTCTTTAATTTTTACTGTTCCAGTAGATAGTTTTGAAGCTTATCGAAATTGGTTGGGGGAAGTTTGTCAGTCTCTAGAGGTTGAACAGGTAAGAATGATTGATGAACCTACTGCTGCGGCTTTAGGTTATGGGATGGCAGATGCGGAAATTTTGTTGGTGGTTGATTTTGGTGGGGGAACTTTAGATTTATCTTTGGTAAGGTTGGATAATGTGATGGCAAAACAACCTTTGGGTTATATTCTGAAATGGGGTAAAAAATCTTATGGTAACAATTCAAGTCAAAAGGCAAGAACTGCAAGGGTTTTGGCAAAGGCTGGAGAGAATTTAGGGGGTTCGGATATTGATAATTGGTTGGTGGATTATTTTGTTAAGAGTCAAGGGATAGAAAAGAGCTCTTTAGTTACTCGTTTGGCAGAAAAGTTAAAAATTCAATTGTCTTTGCAGCAAGAGGGAACGGAGGTTTTTTTTGATGATGAAAGTTTGGAAAGTTATGAGCTGGGGTTGGGGCGGGATGCTTTTGAGGAAATTCTCCGGGAAAATGGTTTTTTTGCTAGTCTTGATCAGTCAATGAGTCGGGTTTTACAGCAGGCAAAAAGACAAGGAATAGAGTTATCGGATATTGGTGCTGTTTTATTGGTGGGAGGAACGGTGCAAATTCCGGCGGTTCAGAGGTGGGTAAGGGAATATTTTGATGCTGGAAAAATTCGTTGTGAAAAACCTTTTGAGGCAATTTCTCAGGGAGCGTTGCAATTAGTTCAAGGAGTGGAGGTTAAGGATTTTTTGTATCACGGTTATGGTATCCGGTATTGGGATAGAAAGAAAAATGCTCATGGTTGGCATCCGTTGATTAAGTCTGGTCAACCGTATCCAATGAGTAGTCCTGTAGAGCTGGTTTTGGGTGCTTCTATGAATAGTCAACCTAGTATAGAGTTGGTTTTGGGAGAGTTGGGTGCTGAGTCTGCTGGTACAGAGGTTTTTTTTGATGGCGATCGCCTTATTACTCGGAAAGTTTCTGGGGAGCAAACTGCTGTACAACTTTTAAATGATAGAGAGGGAGGTCGTAGTATTGCTCAATTAAGTCCTTTGGGAAATCCGGGGAGGGATCGCATTAAGGTTTTGTTTTGGGTGGATGAGTCTAGGTTTTTGAGAATAACGGTGGAGGATTTATTGACGAATGAAATTTTGTTAAATGAGCAGGCTGTTGTACAGTTGAGTTAGGGTAGGAGGCTGTTAGTTAGTGGCTGGAAAAAGAGGTTTTGGAGGGATTTTATTCAATATTATCCTTTTGTTTTAGTATTATATTTAACATAATAATTTAACATAATAATAAAGTTGATAATTGATTGAAAAAAAAATGACTAATGAACTACCAAAAACTGATTCTCTAAAAAAAAAGGGTCGTATTTTTTCTCAAGATTCATGGGAAAAAATATCTTCTCCGGAAGAGTTTGACGAATTAATACAAGTAGTTACTGTTAAAAACTGGCTGTCTTTTTCTATATTTGGTGGTCTAGTTTTAGTGGGTATTTTATGGAGTATTTTTGGTAAAATACCTATTACAGTAACTGGAAAGGGGGTGTTAATTCGCCCTCGACAAGTGGTTACATTTCAATCAGCAATTGAAGGTAATTTAGATTCTTTGAAGATTAGAGATGGAGAGTGTGTAAAAAAAGATGAGGTTCTGGCAACTATTAATCCATCTCAACTGAAAAAACAGTTAGAGTTACAACGACAAAAGCTATTTCTTTTTCAAACTCAAGCATTAGATACTCAAAGGTTAGAAGGTCAACGGACTCAGTTAGAAGTAGATGGTCTGACAACTAAGGCTGAAGGTTTAAGGCAACGTTTGCGAGATACTCAAAGTCTTACGCCTACTTTACAAAGTAATACTTTAGAGGCTCTCCGGGAAAAGGGTCAGACTTTGGAGCAACGTTTACAGGATATGCAGGCTGTTACTCCGAGATTAAAGGAGGAAAAATTACAGGAAATTAATAAACAACGAGTAAGTTTAGAAAAACGTTTGGGGGATGCTAAAAAATTAACTCCTGAATTGAGGGATAAAAAATTACAGGCGATCGCTGAACAAAAGATTACTCTGCAGGAAAGGTTACAAAGTGCTAAAAGTTTAACTCCTATTTTGCGGGATAAAAATGAGTTGGCATTGCAACAACAACGAGAAAGTTTAAAGCAACGTTTGAAAGATGCCCAAGAGTTAGTTCCGGTTTTTGAGCAGAGGCTAACAAAGCGCCAGAAGTTATTGGATGATGGTGCTATTTCTCAAGATAATTTATTACAAACAGAACAGGAGTTTAGGCAAAATTTACAGTCTATTGCTCAAATTAAAACTGAGTTAAAACAAGTAGAGGTACAGGAAGCAGAAACTGCAGAAAAATATTTACAAAATTTCAGTACTATTAATGAAATTGAGGATAAACTGAAGGATTTAGAAGTGGAGGAAGTTGAAACTAATCAGAGATATTTAGATAATGTTAATACTATTAGAGAAATTGAGGGTCAATTACAGGGATTAGATTCACAAACAACTGAAACTTCTAAACAATTTCTGGATAATCTCAATCAAATTAATGAGATAAAGGTGCAGTTACAGGAAGTTAAGTTGCAAGAAACTGAGGCTATGGAAAAGTTTTTGGAAAGTCAGAATATTATGGCTCAATTAAAGGTTGATTTGCTGGATTTAGAAACCCAGAAAAAACGTTTGGAACAAGAAAATTTAGAGGCGGCAAATACTCGGAAAAATCAAATAGAAGAAGTTAATCGAGAAATTGCTCAGTTAGAAAAACAGGTTGCAGATAATAGTAAAATTCTTAGTCCTGTAGATGGGTGTATTTTGGAAATTAAAGGCACTGTCGGACAATATGTAAGTCCTGGTACTGTTCTGGGTAAAATTAATGTTCAAGGAAGGTTATCAGGATTAATGGCAGTTAGTTATTTTCCTGTTAAAGATGGTAAAATGATTAAGTCTGATATGAAAATTACTATTACTCCTGATACTGTTAAACGAGAAAGATTTGGAGGAATTATTGGCAATATTACTTCTATTTCTAGTTTTCCTGTGACTAAGGAAGGGGCAAGTTTTGTAGTAGGAAATCCAGAAATAGTAGAAAATATTATTGGGGAAAGTGGGGGGCAAATTGAAACTTATGCTCAACTAAGAAAGGATGATAATACTTTCAGTGATTATCAATGGTCTTCTTCAAAGGGACCACAAAAAAAATTTACTGCGGGTACGACAATAACAGCACGGGTAAGGGTTGAGGAAAGAGCGCCTATTACTTTTGTTTTGCCAATATTAAGGGAGTGGAGCGGGGTTTATTTATTTAAGTCTAAGTCTTAATATAAGTCAAAGGTTTTTTAAAAGCTACCTGCCCACCTATTCACCTATTCAAATATTTTTCTAAAGTAAGTTTTTTTTTGGTTATAAAGTGGAATTTTGAGTCAAAAGTTACTTATTTAAAGGTTAAAAGCTATAGCGCTAATATTTACTGCTATAAAAGTTCATATTTTTTTGAATTTCATAAGTAAAATTAAAAATAATATGCCTATATTAAATGATAGAATTTGAAAAAAATAGTCAAGCTTTTAGATGAGTGTGAATAACTTATTAAAATTCTAATACTATTCTAGCTTCATCTTTAGTCACTAGCAAAAAAAAGCTGGTTAATTTTGAGTTAAAGTTAAATTTTTGCTTATTAAAGGCTAGCTTGAAAATTGTAACTTTTGAATTTTGATTTTAATATTAATGACTTTTAAAAGACTTTTGACTTAAAATTTGACTTAAAATTTGGGAGTTTAAATCCAAATTGGCTCTTTTAAAGTTTATCCCTTCTGCTTTTTATGGCTTTTTATTGATTTTCTTACTTACCTTTTGAAGCTCACTTGATATTTTCTTAGTCATTGTTTTAAAATCAGCTTTGTTGAAGTTATTCTTAACTTTATTCCACTCATTATTAATTGTTTTCAAGTCAGCTTTGTTGAAGTTACCCTTAGCTTTATTCCACTCATTATTAATTGCTTTAAAATCAACTTTCTTGAGCTCATTCTGAACTTTATGCAGCTCATTATCAATTTTTTTAAAATCAACTTTCTTGAGCTCATCTTTAACTTTATTTAGCCCCTTCTCAATTTCGTTATATTTAGTCATTTTTTTTCTCCAAATAAAATAACAAATTGTTCTAATTTTGATTTTAGCATTACAGCGATGCTAGGGAGTCTATCCCTTTCTAGGGTATAGCAGCGTCGGGAGAATGTCAATGTGTACCATTAATCCATATTTCATGTTCACTTATATCAATTTCATCATTCCAAATAATTCCACTCCCTGATGGATCTATTTGAAAATTTTTGCAGAAAGCAAAGTTTTTTGGAGGAAAGAACGTTGGTTTGTTTAGTAATTTTTGAATATTATACTTTCTTGTTTTATGATTGGAGAAATGTACTAACAAGGTGTAGTTATCTATTACTTGAGCTGATTTGATTTTGGGATAAAGCATAATTTTTATTCGATAATTTATTTTTATGGTGGTAATTTTCTAAATTCTTGGGTATTCTTTGCAATAATTCTGTTTGATATATTGATGCCTATTCAATTACTATTTTTGTTGCTCTATTTGCTAAATCACCTTCAATAATTTCCCAGGTTTCTAGATTAAATAGAGGGTTATATTTTCCATAAATTGCATGAAAATGAGGAGGAGGATGATCTGCAAAAAATAATAATTTTGATAATTCCATAAAATCTGGAAACTTCAGGCATTGGTTTGATTCTCAAAAGCAAATTCCCAAAAATAATTATATTATTACTTGCTCATAAATTACCATTGCTTCCTGTAATACCCGCAAAAGGCGAAAATAACGACTTAGATCTTTTGGAGTCCTCAAATCTACTACTCTTCCTAATAAATAATTTAATTCATCTTCTATTCTAATAATTGCTAAACCAGGAGTTTTTCCTGGCTCAAATTCTACTAAGATATCTATATCACTTTCAGTCGTAAAGTCATGCCGCAGCACTGAACCAAATAAGGATAATTTGCTAATATTATACTGCTGACAAATTTGATTAATTTCAGCTTTTTGTAAATCAATAGGTAAAGTTTTCATGTTTATTGCTAGTTAGATAAACTTCAGTTAAAAATTGGCAGCAAGAAATAGAGTCATAATGTTAATTCACTGACTACTAAAATAGATAACTCACGGACTTTTTTGAACTGTAAATCATTAGTTAAAAAAGCATCACAATTAGACTGAATTGCTGTGGCAATTTGTAAAGCATCAGGTAATTTTAAATTATATCTAACCCGAATATCAGCAGCAATAAGAGCAGTCTCTGAATTAATATCCACAAAATTAATTTTGTCTTGACTCGTCAGAATGTTAATAAATTGTTGTTGTACAGAGAGATTTTTTTGACTGGTTATATGGATTATTAGGATTGCTAAATAATCGGAGCAGAATCTAAAAAATCCGATTTAGCTGTCCTAAAATTGTCTCAATTTTCTTTGAATTTAAACAATTTATTGTTCTCGTTGTTGCCATTCTTGACGTAATTCCTTAACCCATTCTTGAGCATCTTTTCCCTCTAAGATATTAGGTAATATTCCTCGCAAATTACACAAACTATGTTTAGAGGTTTTGGGAATAGTTGTCTGACGCTTCAATTGTTCTGTAGTATAGGTAATGATTTGAAACTTTTCTTCTATAGTAAGCTGTTCAATTTCTTGTAATATTTTTGTTAATAAAGGACTCATTAATTTAACCTCCATAAATAGTCTAATTGGGGCTTGCTGATTAAATATAAAAGCATTGACATATTCTTAATATGTATATCTATTCTATCAACATTCCTCACAGGATTATCAACTGGTACCCTAATCACTACTAATACAGTTATGATTGATTCTAGACTAGAGTTGTAGTAGGTATAAAAAAATGAAAAAAATGTTCAAGTTCAGGCTATTAAATCAAAATTCTATCTCTGAGAATCTCGAAAAATATCAAAGACTTACTTATCCTCCTTATCGTCCTATCCTAGATAATCTTCTAGATTCCAAATACATTGCTATAAGTGCAGAAGATAATCAAGAAATATTAGGATTGACTATAGGAAAAATAGATTATAAAAAAAATATTGGGGAAGTTTTGTCTCTGTTTGTTATACCAGAATATCGAAGACAAGGCATTGGTAATCAGTTATTGGTTGCCCTAGAAACAGAGTTCAGGGGGAAAAATTGCCAACAAATTGATTTGATTTATATTCCCAACCAAACAATTATTGCTTTGGAAAAAATATTTCAGAAAAATGCCTGGTCTAAGCCTAAAGCTCGTATGTTAATTGGTCTGGGAGAGCGAGAAACTATCAAAAACATGGCTTGGTTAAATCTAGATCAGAAATTACCATTAGGTTATGAAATCTTTCCCTGGGGAGAATTAACTTCTAAGGAAAGAACAATTCTTGAAAAATCACTTTGGTATCCAGATATTTTATCCCCTTTCACTGAAGAGGATATTATTGAACCAATCAATAGTTTGGGTTTAAGATACAATCATCAAGTAGTAGGTTGGATGATTACTCATCGAATTTCAGAGAATACTATTCGTTACACTATACTTTTTGTTAAAGAAGAACTGCAATCTATTGGTAGAGGAATTGCTCTTCTTGCACGAGCAATTAAATTAAATTTAAATCATCCTGAAATTAATCAAGGTAGTTTTGCTCTTTTGATTAATAATGAAAAAATGGCTAAGTTTACCGAAAGAAGATTAAAACCTTATTTAGCTTCTTTTCGTCAATCTTTTATTAGTAGTAAGTTAACGTAAAATTCGTAGTTTTTCTTTTTTCTCTCTAACTCTTTTGGCACCTGTTGAAGCACGATCGCGAATTTGATACATCCACCACGGCGCGAATGTCGGGGAAAACGAATGTGTTGGGACTGATTAAACTCCTCTCGGTTTCTGGTAGAAGCACTCTTTTCTTCTGCCTTCAGAGCGATCGCCTCCACCATTCGTCTCGTCCCACATTGACCGCTCCTTTGACGGCTCCTAGTTGTTCTTTTTTCTCTCTTACTTTTGACTTTTGACTTGAAATGAATTATGCCAAGAAAACCTCGGAATTTTCAAATTGGACACTCTTATCACATTACGACTCGTTGTAATAACCGTGAATTTAAACTATCCAGGCGCGAATGTCGGGAAGTATTTCTTTATGCAATAAAAAAGGTTAGCACCAAATACAATTTTCGGCTTTATGCTTTGTGCATTATGTCCAATCATGTTCATTATTTGATTGAACCGTTGCAACCAGAAGATTTACCAAAAATTATGCACTACCTCAACTGGTACACAGCTATGTGTTTCAACAGAATGTTAAAACGTACGGGGCATTTTTGGGAAAAACGATATTACTGCAATGGGTTTCCTTCCTCAGATAGAGAAAGAGCATTGAATACTTTACGCTACATCCACGGTAATCCTAAAGCGGCCAAAATGCGTTGCGGCTTTTTCTATGATTTTAGTAACTATGGTAGCTACGAATGTTTGACTAATGATGGCCTGACTCAATGGCATCCGGCTTTCTTAGAGTTGGCCAATACTCTGGACCAATGTGCCCAGAAATATAAGGAATTTTGTAAGAAATATAAGTCCAAACAAAAAGATTCGAGAAAGTGCCACTGGGGCAGCAAACTTTTAGGGGGTATTGTGCTGTCTTTTGATGGCCGAAATTCTCGCTCTGCTAAGAAGAAAAAGTTATCAACTCCTTTTGACTTTCCGCCGACGGTGATGCCAGACAATGAAGAATTAGCAAAGGTAGTTAGTCAATTTGTTGTAGCTAATAGACCGAATTAGCAGAAAAAAAAAATGTAATACCTAGGTTTTAGCTTTAGTTCATAGTTCAGTTCTTTTAAACTATTTCCCCTAAGCAAGCAAAAGAACTTTTCATAGTTCTTTTGCTTGCTTGGACTCCGTTTTTTTGATATTTTTATGAATTTGTTCATCACAAATCCCAACAACTTTTCCCAAAAACTAGCATTGTTTAATTCGTACAAGAGAAACGGTGTAAATTTTAGGACTTACGCAACGGCACTATGTATAGTAGCAATATCTTGAAAATGATATTTTTTGGCACCATATATAGCGGTACTGCGTAAGTCCTGTTAGTTTAAATTCCTCGAGTAGAACAGAACAGACATCCTGTGGCACAACTATGCCAACTGACGAGTTACCAACTGCCTAAACAACCCCTCCTGTGCCATCAACTCATCAAACCTTCCCTTCTGCACAACTCCCCCCTAGAGAGACATCACATAAATAACATCGGCGTTCCTCGGCGTTCCTAGGCGGGGGTGCCAGGTAACAAATAAAGAATGTGAAAAAGGGCTTATGTTTAATGTTATGTATACAATAACCCTTAGGGTTCTACCAATAACCCTAGTTTTGGTTCCTTCTCTTTTTATTTTTTCTTCATTCCTTTCAACTGGAGTTGTTCTCAAGTTACGCTCTCTAATTATTAAGTTCCTCAAGTTCCTCGTAGTGGGCGGCGTCGCCCGGTTGCGAGGTTTCGGTTTTTGGTTTTTTGGTCATTGCGTTCATGGCGTTCATGGTCAACTCCTTTGTTTTTTTTGTTTTTGGTTTAGCGTTCTGCTAATAGCATAGCATTTCTTTTGTTTTTTTTGTGGCGTTTTAAAGTTTTATTAATTAATAGTATTCATATTACAGTTAGTTAATCTAATCTGTATTCATAAGTTTTATTAATCTAATCTGTATTCTTTCGTTATTTTGTATTTCGCTGCGCGGCTATTTCCTCCCCTAGTGTAGCCGTTCCGAGTCGAGAGTATGTTTGTTTTCGATTTTGTCTGGATTTCGTCCGCGTTCGGTGGTTGGGTTGCATTGTGTTATGTCTTCTCTCCCACCGCGTTCGCGTAAAATCTTAATTATAAATCTTCGTTGAATATAGAAAAAAAGAGAAACCTTGATGTGTATGGTCAAATTGTCTAAGCAAATAGACCCTCAAAGTGGGGAGGAAAGGATTTTTTTGCTTTCCCTTCCTGTCGTTTTTATTTCGACAACTGGCTCGTTTTAACGCCAACCACCTTGCGCCAAAAAACTTGCGTAGTAACTATTCCAGTAACCACCCGACCAGCGTTCCATTTGGGTGCAGCCGGCCGGAGCGCCATAGCCACCACAAATTTCCTCCAATTTGTGAGTTCCTATTCTTTTCTTTCAATTATTTACTGCTTTATTTTTTTTAATTGTTTCTCTTATACATCAGTGCCATCAACTATGCCAACTGACGATTTACCAACCGCCTAAACAACCCCTCCTGTGCCATCAACTCATCAAACCTTCCCTTCTGCACAACCCGCCCCTGAGACATCACATAAATAACATCCGCGTTCCTAATAGTACTCAAACGATGAGCAATAACAACCCTGGTCACATTCAACCGCTCCAAACTCTCAGTAACGATCGCCTGAGTTTTATTATCCAAAGCACTAGTCGCCTCATCCAACAAAATAATTTTCGGCTGCAATATCAACGCCCGAGCAATTAACAACCGTTGTCGTTGCCCCACGGAAATATTACCACCTCCCTCACTCACTATTGTATGCATCCCCATAGGCATTTTCTCTATATCATCAGCAAAACCCACCTTCTGAGCGGCCTCCCATGCTACCTGTGGACTTACCAACTCACCACTACTAATATTTTGATAAATACTACCCGTGATCACCTGACCATTTTGCAGCACCACCCCTAATTGTTGTCTAACTGCCTCCAAGTCTAATTCAGCCAAATTTTTACCATCATAAAAAATACTTCCGGTTTGTGGTTGCTCAAACCCCAACAACAAACGAAACAAAGTAGACTTGCCACTGCCAGAGGGGCCCACAATAGCAACAAATTCTCCTGGTTTAACTTCCAAACTAATATTATGGAGTACAGTCACCCCATTAAATTGTGGGAGATTTTCTTCAGTTTTGCCAACTATTAATTTAGACTTTTGATGATAACTAAAAGTCAGATTATCAATAGAAATATGACCTTGTAATTTTCCGGGGTGAGCCAAATTAGGATTATATTCAATAGGAGAATCTAAAATACTTTTAGCTCTTTCCCACAAAGGCACAATACCAATAACATCAGTAATAGTATCACTCAAAGAAGTTACTCCACCAAGAAACACACCCATGGCAGAATTAAAAGCAATAAATGTACCAATATTTAAACCAGGAGTTCCGGTCTGAGCCGCAGAAATAATAATCTGAATAGCAAACCAATAAATCACAATAGAAGTCACCAGAGAAACCACTTCATTAATGACAGAAATAATATCGTTTATCTGAAAAATCCGATTATTAAGTTGAATTTGAGGTTGAAACTTTTTACCCCAAACTGCAAAAGCTCTAACTTCTGCAGCCGCAACTCGTAATTTTTGAATCCCATTGATGAGCTCTACAGTTAAACCTTGAATTTTCCCGCTCAACTTTTCTTGTTCCCGTTCAAAACGAATTAAAATTATTCCAGAAATCAAAGTAATGAGGAAAGAAATTACACCAACAATTAAAACTATTAAAGCTAATTTTTTGCTATAGACAAACATTAAACCCAAATTTAACAGAGAAAATAACCCAGTAAAAATAGTCGTAATTACAGCACTATTAACCAAACCACTAATCTGACTTATCGCAGCAATACGAGTTAATAAATCTCCCAAACTAAATTCCCGGAAAAAAGTTGGGTTGAGCCGAAAAAGACGGTCATAAATTCCAGATTGTAAATTAATTTGCATTCCCTGAGAAACCTTAATAGACATTATGCCTTGGAGCAAACTAAACAAAGATTTTCCTACAGTAACAGCAAGTAAACCCAGTGCTATTTGCCATAATAATAATTTGTCACTATCAGGAATAGCATTATTAATAAGAATGGCACTTGCCTGAGGAGTAACCATACCCATCAGACTGATTATTGTGCCTAAAATCATTACTTTTATTGCATCCCATTCATAACCTTTGATGGCAAATAAAAATATATCCCAAACCTTTTTAACTTGGATGGGAAAAGGGCGATAAAAAGTAAATGCTGTTGATGATAAAGTAGCAGCTACATTTTGATTTATAGGAATAGAAGTTTGAGTCTTTGGGTTGTAGAGAAAATATTGATTATTCTTAGGTAATAAAGCCACGGGTAAATTTTCTAATTTCAGCCAACCCAACAAAGCACCAGAATTTTTTTGCCACCATTTATCTCTGAGTTTTACTTCCCGAATTCGACAACGTGAAGCTCTAGCAATTTCTTGTAAATATATTTGATAATCAGCAGGAGATTGTTTTTCTGGGATAGTATTTTGGAAATTTTTTCTTTGTGTAAGTGGTGGTTTAATTTCTATCTGACTAGCACGACCTATTGCTCCTACTGCGGCTAATAATAAGTCATTAAAATCAGAGACCAAAGAGTTAGTTGTTTTTCGATTATATAAAACAGAAACAAAATTTTGCATAGTTTCTGCTTGACTGCGTTGATTATAGGTTTTGAGTCGTTGAGAATTGAAAATTTCTGTTTGTTCCTCAGCCAAAATAACTTGGTGGAGATAATTGCAAAAATTATTATTAATTGAAACAATTTCCGAAAAATTAGGAAGCTCAGATTTTCCAAAAGATGGCAAAGAAAAATCTTTTGGTATTGAGTCAACAGATTCATCTATCAATTCCAAATTTTGAATTTTGGCTTTTGAATTTTGACTTTCCCAAAGGTAGTTTAACCATTTTTCTACTAGAGAACCAGACAAACTCTGGAAATCTTCATTTAAATCTGTATTAGCAAGATTAATCTGAATTAATTCAGCTTTTTCCAAAGCAATTCCCAATAATTTGCCTTGAGTCTGAGCATCGGAATTAAAAATTAACTCTCCCTGTTTAACCGTAAATAAATAATGACGATTTCCGATTAATTCTCCATCTAATTCCAGAGAATAAAATATTTCCACAGCTCCAGATTTTACGAACCAGATAATTTGGGGGAATTCAAAAATTAGAGGTTGATTACCCTCCAAAAAATAATATTTTGTTTTACTGTCTAAATTAGCCAATAACCGAGTAGAAACCAGAGACTTTTCAACAATATTTTCCCCTTTTATTTCTCTATTTATTCCCAACTCTTGATACCTTAGTTCAGGCAAAATATCCTGCCTAAAATCTTGACTCCCTTCTTCCATCTCCAATAATTGACGATAATAAACACCCTGATGCCAAAGTTGTTGATGAGTACCTCTTTCTAATACCTTTCCTTCTCTTAAAACAATAATTTCATCACAATCTCGAATTGTACTTAAACGGTGGGCAACCACAATACAAGCACAACCCCGACGACGTAAATTCTGATCAATAACTCTTTCAGTTTCCGCATCCAAACTACTCGTTGCTTCATCTAAAATTAAAATCCGAGGATTATTTACTAAAGCTCTAGCAATTTCCAAACGTTGTCTTTGACCACCCGATAAATTCACCCCACCTTCCAACAAATTAGCATCATAACCACCAGATAAACTGATAATAAATTCGTGAATATTTGCATCCTTACAAGCCTGAGTCAAAGCCGAATTACTAATAGTTGGATTCCATAAAGTTAAATTTTCTCGAATTGTACCTTCAAATAAAGATATATCTTGTGCCACCATAGCCACCGACTTTGTTAAAACAGAACGAGGAATTTCTTGACGGGGAATATCATCAAATAAAACTTCTCCTAATAATGGTTGATATAAACCGCAAACTAAATTAGCAATAGTAGATTTTCCAGAACCACTTTTTCCCACCAAAGCAACTCTTGAACCAGGATTAATCAACAAATTAAAATTGACAATTAATGGAGGCTTTAAAGGATTATAACCAAAAGTAATATCTCTAAGTTCAACTTTACCTTTTAATGGAGAATATGGAATTAATAACCCGTTCGGAGCATTTTTTTTATCATAAAATGTCAGTTGTTCCAAATTATTTCCGGCTTCAACAACAGAATTTTCTACATCATTTTCTACTGCTTCAGTAATTTCAATATCTTCATCAAGAGGATTATCCAAAACATCATCAAGACGTTCCAAACTTGCCTCCAACTCTTGTAAACTACTGGCAAAATTGATTAATTTGCCCAGAGGATTCAAAAAACCAGAAGCTACAGTTTGAAATGCCACTAACATCCCAATACTCATGTCTCCTGCCATAACCGTTAAACCTCCCAAAACCAAAATTATTGCAGAAGAAAGAGTACTTAAAAATGTTGGTAAAAGAGTTAAAATTTGAGTTTGAATATTTAATTTTTGTTCCTCATTCATCACCTGAGAATATATCCCCAAAATCCGGGAAAACATATAAGATTCTAAACCCCCCGCCTTGAGACTTTCAATTGCTCCTAAACTACCCAAAAGATAACCAGACAATTTACCTTTTTTTTCGCTCAAATTCAAAGTTGCCTCAATCCGAAATTGTCGAAGCCAATATAATGCTGCCACATTAATCAAACCAAAAACTATAGTAATTCCAGCTAAAACTCCATTATAAAAACTCATTAAAACAGCATAAAATACCAACATTATCGTATCAATAAAAGTATTTGCAACCTGACTCAATAATTGTACAGTTGTGTCATTTAAAGCAGCCCGAGAACTAATATCTCCAGTAAATCTTTGGGCATAAAAATTCATAGGTAATCGTAACAGATGCCACATAAACTTACTATTCATAGTAATTGAAAGTTTAATAATTAACTTCCGCAAGAAAATATATTGCATCCTAGCAATAGTAAATTGTAGAATCGTAGTTACCGCCATTCCTACAAGTAAAGGACGGAGCCAACCTTGCAAACCCTCCACTAAAACTTGGTCAACAAAAACCAAACTAAAAGCCGGAATAATTAAACGAATTAAACTGAGAAAAAAACCAGTAATAAAAGTAAAAACCAGAGCATTTTTCGAGTTTTGTAAACGAACTGCTAAATAAGCAATAAAATTTCTTTTTTTTCCTCCTTTAACAAACTCTTCCCCCGGTTCCATCTGCAAAACAATACCACTGTAAGATTGAGCAAATTCTTCCTTACTAACCTTGCGCCTACCCAATGCCGGATCATTCAGATAAGCAAACTTTTTATCAAAACCTTCCACTACCAAAAAATGATTAAATTTCCAAAAAATAATCACAGGTAAATCAATTTCTTCTAAAAATTCAACGTTACTTTTTCCACCCTTAGCTGTCAAACCATATTCCCTTGCCGTTCTGACAATTTGTCCGGCATTAGTACCATCTCGACTCACACCGCATTTACTGCGCAACTCCATTAAAGGAACTTGACGCCCATAATATTTCAGAATAATACCCAAGGATGCGGCGCCACATTCAGTAGCTTCTCTTTGTAAAAAAGGTTTTGTTTTTACTCTCATTTTTTTTTCCTTAATTTTTTTTATTTGTGATAGAGATATAGCTAATAAAATATCAGCCTTCCCTTTCAACTTCAGCAAAATATATTGTCAAAATACGACTATGATATAAAAGTACGCTTATGATGTATAATTTTAATTTTAAGACAGATAAACAAAAGAAGAATTTTACACTATAATTAAATAACTAACATGTCTAGTTTTATGTCAATATCCTCTGATAAAATTTAATTAAATTATATATAAACTAACTAACTATTAAAATTATAAAATTATATTTTGCTTGTGAGATATTTGTATGAAATTTTCTCATATTCCTTTTTTTTCAAAAATTTAGCAGTAAAAAAAAGTAAAAACACTTGATGTATAATTTTAATTTTAAGACAGATAAACAAAAGAAGAATTTTACACTATAATTAAATAACTAACATGTCTAGTTTTATGTCAATATCCTCTGATAAAATTTAATTAAATTATATATAAACTAACTAACTATTAAAATTATAAAATTAAAATTAATTAAAATAAAATTGTGAGATATTTGTATGAAATTTTCTCATATTCCTTTTTTTTTCAAAAATTTAGCAGTAAAAAAAAGTAAAAACACTTGATGTATAATTTTAATTTTAAGTACAGATAAACAAAAGAAGAATTTTACACTATAATTAAATAACTAACATGTCTAGTTTTATGTCAATATCGTCTGATAAAATTTAATTAAATTATATATAAACTAAATTATATTAAATTAAATATTTTGCTTGTGAAATATTTGTATAGAATTTTCTCATATTCCTTTTTTTTTCAAAAATTTAGCAGTAAAAACACTTAAATTTAAACATAAGTTTCAAGTTTAGTAGGTATGAAAAAACTTAGCTATATTAAGATTTATCTACTGACTTCAATATCCTCTAAGAGATTAATTAACATTTTGACAGACGACAAATTTCAACACTGACCTAATTAATAAATAACTAATAACTAATAACTAATAACTGATGACTGAACCTATTGCTGAACCTATTGCTGGATATACTTTACCTGTATTTGCTTGTGCTGCTGCCGTAGCTGCTCTAGGTTGGCTACGTCAAAATGTTTCCTCTTCATCTACTGTATCAATTAACTTACTAGAACCAAGAGAAATTGTTGATATTCCTATCCAACAGGTAGCTTTACTGAAAAATAATACTGCTTTAGCCGTTACTCGTTCCGATCCCGGTAATAATCTTGACCTAACTCATAATACTCCTATTTGGGCTATGGTAGAATTGGTAAAAGTTTGCCAAACTGACACTTCAGAAAAAATTGTGATTATAGGTGGAGAAGGAATAGGATATGATATTAATAGTAGAGAAGCAGCTATATATAATTATGCCCAACGACTGCTCCAAGAAAATCTTCAACCCTTGCTCAAGCAAAATGAACAAGTTATAGTCACTATTATCCTACCAGAGGGTCGTCAATTAGCGGCTCGGACTTCTAATTCTGCTTTTGGTATAGTTGAAGGTCTTTCTTTGTTAGGGACTACTGGGGTTTCTCAACCTTTAAGTGTGCCTGGACAACTTGAAGTTTACCAAGAGGAACTACAACAAAAGGCGGCGCAGTTTCAGAGTTTGGTGTTTTGTGTAGGGGAAAATGGTCTAGATATAGCCAGGAAAATGGGTATCTCTCCACAGCAGACCGTCAAAACAGCTAACTGGTTGGGCCCAATGTTAGTTGCTGCTGCTATTGCTGGAGTGGAGTATATTCTATTGTTAGGCTATCATGGTAAATTAATTAAGTTGGCTGGTGGAATTTTTCATACTCATCACCATTTAGCTGATGGACGATTAGAAATTTTAACAGCTCACTGTGCAAATATAGGTGTACCTACTTCTGTAGTACAAAAAATTTTTGCTTGTCCTACAGCTGAGAGTGCTTTGAAGCTGCTGCGGAGTATAGATACAAATCAGAAAAATGATTTGGTAGGTAAGGTTTATGGAGCGATCGCTTCAAAAATTGACCAACGTTGTCAAGCTTATATTTTTAATCATAGCCAAAAGCAAGTCCAAGTAGGTTCGATGTTATTTGACCGCGATCGGCAAATTTTCCTCAAAACTAAAGTTGCGGATCAAGTTTTTTCCCAAATTTTTTCCTTTGAAGATCATAAAAAATAAAGAGTAGAAATTTTAAATAGTCAAGTTTAAGTTAGCTGGGGACCAACTAATAATAACTGTTATTTAAGTTGGCTAAAAGAACTCAATAGTGTTTTAGTAAAATCATGAAAACTAGTAGAAACCGTTACTTAAGCTAGCTATGAGAACTATTACTGTTGTGGAAAATCATTTATTATTTTCAAAGTACGCCAAGTAGGACTTACCAAAAATATCTAAGATCATCTGAGAAAATATTTCCGCTTGTTGCTGCCTTGTAAAGAAGAATTTATTAAACTAGGATTTTTCGAATACCATTATACAGACTTCCTTTTTCACATTCACTTTAAGTTCCAATAGTTTCCACGACTTAACCAAGAAAATCTGTAAGTCCTGGAATGAAATTACTGAAAAAAAATACGAGCTAGAGGAAAATTGTTGTGCCTGTATTGATGTTGGATTAGACAATTTAGCTATATTAATTGTACTTCAAGCCGGAATTAAACCCAAGAGTGATAAATGGCAGACCATTAAAATCTATCAATAAATACTAAAAGAAAGTTAAGAGTTGAGCTTATCTTGCAATAAGTCCAGCAAAATCAATCAAGCCGACTACTAAAAAAGCTCAATATGTTAAAAAAAAAGAAAAGAGAATTCTCCCGACCGACTTATCTCCATAAGAGATTTAGAGGAACTTTGTGATTTTAGGCCTTTATACAGGAAGCACCAATATCAACTTAGGGAAAAGAAGATTTCAGATTTCTTGAAGTGTCCCCTATAATAAGTTAATTGAAATGTTATCTGATAAAGCCTCAACATGCTTAGGGATAAGTGTAATTCTAAAAGCAAAAATCTTATAGTTCAAGATCAAGTTTTATAGATAATGATGTTCAAAAATTAAAATTGACTTGAATTATAAAAGGCCAAAAATATTAAGTCACTTTTTCTTCTAAAAAAGTAAAAAGAGAAATGCACAAAGTAACACCAAAAAAAGATTAATCAAAGAGTAATGTGAAGATATCGGGATTGATCGAAAATTCCCACAATGAGAAAAGTAGCTCCCTTACGTTTTTGACCATGATGGGATAATTAGTTTTATAGTTCACCCCCAAATTGAGTAACATCTGGAAAATAAGGATATGTCTTATGTGACTATATTTTTATGAACTATATACCTATAAAAAACGAATCTACAAGCTTTTGTAGAAAGGCAGAAATTTTTTTTTACACTGAGAGTGTGTCAACAGAAAAATTTTTCTCACAATTATTTATTAGTTTGGCTAATAACTCAGAAAATAATTGTTACTAACACAAGAAAATTAATCATTAAAGTCCAACACAATAAAATATTAATCGTGACCCTAACAACACAGACACAAAAAAACTCAGATTCTCTCACTCAATTTAACCGTCAAATGATCGTAATTTTGGATTTTGGTTCTCAATATTCAGAACTAATTGCCCGCCGAATTCGGGAAACTCAAGTATATTCAGAGGTTATTTCTTACCGCACAACTGCAGCTAAACTGGCAGATATAAACCCCAAGGGAATCATTCTTTCTGGTGGGCCAAATTCTGTTTACGATGAAGGGGCACCTCATTGCGATCCCGAAATTTGGAATTTGGGAATACCCATTTTGGGTGTATGCTACGGTATGCAGTTAATGGTAAAACAACTGGGCGGAGAAGTTGAACGCACTCAGTTAGCTGAATATGGTAAAGCATCTGTATCAATAGATGATCCTACAGATTTGCTAACAAATATAGAAGAAGGTACAACTATGTGGATGAGTCATGGAGATTCTGTCACCAAAATGCCTTCTGGTTTTGAAGTATTAGCTCATACAGATAATACTCCTTGTGGAGCAATAGCTGACCACAATAAAAAGCTCTATGGTACTCAGTTTCACCCAGAGGTAGTTCATTCTATTGGTGGTCAAGTATTAATTCGGAATTTTGTTTACCATATCTGCAAGTGTGAACCAACCTGGACGACAGAAGCTTTTGTAGAAGAAGCGATTCGAGAAATTAGAGCTAAAGTAGGGGATAAACGAGTATTATTAGCTCTGTCTGGAGGGGTAGACTCTTCGACTTTAGCATTTTTACTCCATCAGGCCATTGGAGATAAATTAACTTGTATGTTTATTGACCAAGGGTTTATGCGAAAGTATGAACCAGAGAACTTGGTAAAAATATTTCACGAATCTTTTCATATATCAGTTAAATATGTGAATGCTCGCGATCGCTTCTTATCTATACTCAAAGGGGTCAGTGATCCAGAAGAAAAACGGAAATTAATCGGCCATGAATTTATTCAAGTATTTGAAGAAGAGTCAAAACGTTTGGGACCTTTTGATTATCTAGCTCAAGGTACTCTTTATCCAGACGTGATTGAATCTGCTAATACGAATGTTGACCCCAAAACCGGGGAGCGAGTAGCGGTTAAAATTAAGAGTCATCACAATGTTGGTGGTTTGCCGAAAGATTTGAGATTTAAATTGGTCGAACCTTTGCGCAAACTATTTAAGGATGAAGTGAGAAACGTTGGTCGTTCTATTGGCTTACCAGAAGAAATTGTGCGACGACATCCTTTTCCTGGCCCGGGATTAGCAATTCGGATTTTAGGGGAGGTTACAGACAAACGTTTGAAAATATTACGGGATGCTGATTTTATTGTGCGCGATGAAATTAGGCAGCAAGGTATGTATCATGATTTTTGGCAAGCGTTTGCTGTTTTGTTACCTATTCAAAGTGTTGGGGTAATGGGGGATCAACGTACTTATGCTTACCCCATTGTTTTGCGGTTTGTTAAGAGTGAGGATGGAATGACTGCTGACTGGTCTCGTGTACCTTATGATTTGTTAGAAACTATTTCTAACCGCATTGTGAATGAGGTTAAGGGAGTTAATCGGGTGGTGTATGATATTACTTCTAAACCTCCAGGTACTATTGAGTGGGAATAATATAGTACTACGGTTAACTCCTAAGTCGGTAGGGGGTTTGGCTATCAAACCCCCTACTATATTTATTGAATAAATTGGAGTTGTGGGAGTTAGGAGTAGTAGGAGAAAATAATCATCTATCATCTCCAAAAATTGACTAAACCCTTCTATCCTTTTACGAAAGCTTCTTAATCATTGTTAAACATACATAAGCGATCGCAATACTTTGGGATGAGTTTGAATAATGCAAAATATTAACCCAAATTTACCAAAAAAGACAAGTAAATAATATCACTTGTTTTATGGTCAAAGCTACAACAACGACTTTGCTGTTTGTTTGCTTAGAAAAAAAGAAATTAAAAGTGTGTCAAGAGGAAGTAAAATAGTTATAAAATCCGAGTTTGTCTTTGATGTGGAATATCTGGCACTATATAATATAATTGAAATTTTGAAATTTACCGTAAATACCAACTACTATCATAAAAAAAACAAATGAAAGTCATTGAAGTAACAGGAACTTTTAACAAAAAAGGGCAATGATTCTTCGATCGCCATGTTTGGAAAATTCAGCCCCAGGAAAAGCGCGAGTTATACTACCCTCCCAGGAAAAGCGGGAGTTATACTACTCTTTCGCGAAGTAACAGAAAAAATTGAACTCGATCCAGATGATACTCCCGTTGCCAAAATAAAAGTTAGTCTCACAAGAACATTGCCAAAAGCAAAATCTAAACAACCCATTTCCTTTTCTCAAATGTGGAAGGAAATAGATATCGAATAATATTCCTGTAGTTGAGATTGACTTAAAACCTAAAAAGAATAAGAAATCTGCGGAAACTCTTCCCAAAATATCCTCCTATTGAGCTTAGATACTCAACCAGTTATCGAACAAATACTAAAGAAATAAATTTCGAGCGCGATCGCCTGAAGCGACGTTTTCAACCAAACTAAATTATTATGATAAATTTATGTAAAACACTGTAGTTCCATTATGCCTCAGATTCGATTCCCTCAAACTAAAAACCAAATAGTAATATTGAGTTGTGTCGCTGTTTTCTTATGGCTGTTTAGCTGTACTCCCAACTCTCCAAAATCTCTACCTCTAGCAGAATTAAAACGGAGCAAAGAAAGTATAGTAGTTTCAGCTCATCCCCTAGCTAGTGAAGCAGGAAAGTTAATGCTAGAAAAAGGGGGCAATGCAGTAGATGCAGCGGTAGCTACAGCCTTTGCTATTTCTGTAGTAGAACCATTTTCCGCAGGTATTGGAGGTGGAGGCTTTTTACTATTAGGAACTCCTCCAGAAAATTCTGAGACTCAACAGTATAAAATTCGAGCCCTAGACTTTCGGGAAAGAGCTCCTAAAGCAGCAACTCGAAATATGTACCTTAACGAAAAGGGAGAAGTAGAGAAAAGAGCAAGTTTAGATGGACATTTAGCAGTCGGAGTACCTGGAACCGTAGCAGGATTGTATAATATTCACAAGTCCTTAGGCAAGTTACCTTGGAAAGAATTGCTAAAACCAGCTATTCGTTATGCTCGTGATGGGTTTGAGCTAAGGGATGACTTTGTTAGTAAACTAGAAAAACGCTTAGAGGTAATTAACAAAAATCCGGCAGCTAGGGATATATTTACTAAAAATGGCCAAGCTTATGAACCAGGAGATTTGCTGATTCAAACTGATCAAGCTCAAACCTTAGAAACCATTGCTGAAAATCCTCAAAGCTTTTATACAGGTAAAATTGCTCAGGCGATCGCTACTGATATGGCCAAAGCAGGAGGTCTAATTACTTTAGAAGATTTACAGAACTATACACCAATATGGCGTGAACCTATTTGTGGCAAGTTTAGACAAGCAAAAGTTTGTGCTATGCCACCACCATCTTCTGGAGGCGTACATTTACTACAAATATTAAATATTGTGGGAGAGACTAACTTGCAACAGTGGGGTAGGGAAAATGCTGATACTATTCATTTACTTACTGAAGCCATGCGGGTTGCTTATGCCGATCGCTCTTTGCATTTAGGGGACCCAGATTTTCTGGAAGTGCCAGTCAAGGAGTTGACTAGCTTGAGTTATGCTCAACAACGACGTCAGGAAATTAGTCTCACAAAAGTCAGACGTTCCACTGAAGTACAACCAGTATCACCAGAAGTTCTCAGGAGTAATATTTTGGAGTCTCCTGATACTACTCATTTAACCGTAGTAGATCAAGAGCGAAATGTTATTAGTATGACATATACAATTAATGGTAGTTTTGGTGCTGGAGTGGTAGCTGCTGGTACAGGAATATTGTTAAATAATGAAATGGATGATTTTGCCGCTGCTCCTGAAGCACCAAATTTATACGGTTTGGTCGGGGATGAAGCGAATGCTATAGCTCCGAGAAAAACTCCTTTGTCTAGTATGACTCCTACTATTGTTACAGACAATGGTCGGTTAATTATGGCGACTGGTTCTCCTGGGGGTAGTACGATTATTACCACAGTTTTGCAGGTTATATTGAATGTGTTAGAGTATAAAATGAATGTTGCTGAAGCTGTGTCGGCTCCACGTTTTCACCATCAATGGCTGCCAGATAAGTTAATCTTGGAAACAGGGGGGTTTGGCGAGGCAACTGTGAATGAGTTGAAACAGCGCGGACATAATGTAGTAATGCAACGTGGTTGGGGTAATGCAAATGTAGTTTTCCAGGATGAGAGTGGGATGTTGGAAGCAGCAGCAGATCCTCGTGGGGAAGGGGAGGCAATGGGGACTGGCCAGTAGCTCACGAGGGTAGGTTTTTGATTTTCTGGTTGTTACAATATTTGGAAGCGTGGATATATAATACCAATTTTCTAAAGCCAGACTACACATACCTTGACATCTTGGTTTTCAAGCTTGATAAATTACTTTTACAAATGTTGTTTAAGTTTATGAAATTAAGTTTATGAAATTAAGTTTATGAAATTGGTATAAGAACTATTTACTTTAATGAAAGTAGTTTCAGTAGAAGGAAGCTTTAGTAGAGTTTATCTACAGGATAATTCCAACCAACGTCTTTGTGTTTTGGGTCGATATTGGGTTTTATTACCTCAACCCAACCTACAAATACTCTTAAGTTTCTTCTCATTAATTTCCTTCGTAATTATTTGAGTTTATCTAGAAAGTTTTGAGATCCCTCTTGATCTGCTTGTTGTTTATATAAGTCAGCAGCTTTTTCAAAGTCTTTTATGGTCTGTTGCTGATCTCCAACTCCATGGAGATAGTAAACACTACCCCGCCCATAGCAAGCATCAGCTATTCGGGTTAGAGTTAATAGCTTGTTAATATTCAGCAAGCGCCTTTTCATCTTCTGGTCTGAAAAACGTAAATATTACCCCGGTTATAATAGACCAAGAAATTGCCAAAAATAATCGGAATTAGCATTTTTGGGAACCCTTTGAATACCTTGGTTAAACTCAGCGATCGCTTTTTCATCTTTTCCCTTATCCTGATAAAAAAGAACCCTGCTTGTGTGCCCAAGCATCTTAAGCATATTTAGGGTTCTAGTTGAATAGCTTGTTTATAGTTAGGGAGAGCCTTTTCACATTCGGATCTAAATAACATAAATATTACCCTGGTTACCATATTCAGCGATCGCCTTTTCATATTTTTCCTACTTATTGTTAAAAAAGACCTTAGTAAAATGCTATTAATATAATTTTGGGCAATTCAAAGTTGCCATTTTTTACTAAGTTTTCTATCCGTTCTACTAAACTTACCCAAACTTAAATGAATTGGAAATTGCATAAGCTTTGGAGCTAGCTTCGGTGTTTCACCCATATAACACTAAGTGCATTCTGTAACTTATCTTCCCTATCCGACAACAAAACCCAAGTCAGCTCAAGCTACTTATTCATATTCAGGTTTTCGATCATTACTCATACTCCTACAATATTGCTATGTATGTGTAACTGTAAATAAGTATAGTAAATTTTTATTTAACTCTCAAGTCCCCTGATCCAAAGGGGGAGGAGGTTGAGTGATATTCAAGCAGATAAATGCCAGTAGTACTCACATTAACCATGTTAATATTCGTTTCATAATTTGTAAGTTCTCAAAGTTTTCTAAAGACAGTGTTATCATAAAATAACTAATAAACAAATTTTTATTAACTTAACTTTAATCTAAACGCACTGCTGCTATATACAGCGTATTTTTTGCAATTGTTTGAGATATTTATACTATAATTACTATCTGATTAATTGCGGTCTAAAATATGACATTGGCTTATATCATGTCCGCTTAAATACTTATATTTAACAGAAAATAAAGTAGAGAAAAAACTCACTAACTATTTTTAATTTTTCATAACAATTACCAACTGCTAACTACCTATTTAATATTGAGTCGAGCCGCTTCTAAAATCAAACGTTGTTCAGCACGAGCAATCGCTTTATAAGTCTTTTCAACAGCATTCAAATTAACAGAAATAGAAGTAATACCCCACCGAATTAAATCATCTATTATTTCTGGATATAAAGCAGGAGCATCCCCACAAATAGAACAAGGAATACCAGCACTTTTAGCCTTAAAAATTAAATCTTTAATTGCCATCATTACTGCTGGGTTACGAGTATTAAAATAACTTTTTATTTCTTCTTTTTCTCGATCTACACCTAACAATAACTGAGTTAAATCATTAGTACCAATAGCAATACCTTGTACACCTTCTTTTACATATTCAGGTAATAGGAATAAAACTGATGGTACTTCTGCCATAATCCAAATTTGAAAATGATTTGGTTTATCCTTCCATTTTGTCTCAATTCGACTCCTACAAAATTGAAACTCTTCTAAAGAACGTACATAAGGCAAAATTAAATGAATGTTACTATAACCTAACTTATATACTGCAGATAAAATATTTATTTCTAAATCTAGTAACCTCGGTTCCAACATATAACTCAATGTGCCATGTTGTCCTAATATGGGATTATAATAATTACTTTTATAGGAAAAACTTAACTCTTGAAATATATTTTGATCATGAATATTTTGACTATACTGATTATCTTGATTATTAGGATAATTTAGAGATGAATGCTCCAGTTTTTTCGTCATATTTTTTTCTTGATAACTATAATTAAATAGCACTAAATCAAAAGAACGATAAAATACTGATTTGGGAGCAAAAGCAGCAGCAAACTGAGTTAGATTCTCTACCATTAAATCTATTAATTCTGATTCACGACCTTGTTTTATCCACCATAAAGGATGACGATTTTCTAACAGTTCAATTGCCATTAACTCTGACCGCAACAATCCCACTCCATCTATAGGCAAGTTTTGAGCTTTTTTAATTGAATTAATTTGACTAATATTTACAAATAATTTACTGCCAATGGGAAACAATGTTTTAGAATGAAAAGATTTTTTTTCTACTTCTATATCTAGTTTTTTAGGATAATTTTTATGTTTTTTAACTAGATGTACTTCTCCATTATTACCATTAACTAATAAGTAGTTACCTGTTTTAATTATTTTAGTAGAATTGGTAGCTCCGACAATAGCAGGAATCCCAATTTCTCTGGATAAAATTGCAGCATGACTTGTGATACCGCCCTGTTCAGAAATTATCCCAGCAGCATTTTTTAGTAATGGCAAATAACTAGGAATAACTGCTGATACAACTAAAATTTTTTCTTTATAAACCTCTTTTAATTGTGGATTAAAATCCTTAATAACTACAGCTTGAGCTGTGACTTTTCCTTCTGAGACTCCTATGCCTGTAACTATAGGGGAATCAAGTTTTTCAAGAGATTTTTTTTGCTTTTCTCTTGTTAAAGCAGTTGAATTTTCTGATTTTTTAGACTTTGTTTGCATATCCTTAAAATCTGTAATTAATAGTTGATTTTCTTCATGATTATCACTTTTAAACAAAGTCCATTTAAAATAAAAACTAGTAGGAAATTCATTGGTTATTTTCTTAGTAATTTCAAGCAATAATTGTAAATATTTATCTCTCAAAGCAAATTCTTTTTGTACATTTTCTGGCAATAAAAAAGCTTGTAATCCTAGTAAATTATCAGGAATAGGCATTTGAGTATTATCAATTTCTTGCCATGTATTGATATAGCTTACTTTTGTCATAGCTGTATCAAGGTTATAAGCGATAATTTTATTCCCTAGTTTTTTTTCTTGTATAGTGTAATTTTTAGGAGAAATTAGAAAAGAGTCAGGGATAACTTGCCCGAGCTCAATAGATATTCCTAAACCATAAGTTGCTTGAATTTCCCAACTATTTGCAAAAGCTTGCATAGTTCCTGAAGCGATCGCTGATTGTAAAGATTGTACTAAAATTACTGGTTGAAGTTTTTGAATATCAACTTGGTGAATATGCCAATACAATAAACTTTTAGCTTTAAAGATTTCTGACCAGGCCTGTTTAATTACTTGAGTAAATTTTTCTGATTTAGCTTGACAGATTTTTACATCTAATATCCCAAAAGTTTCCAGTTTAGGAGAAGCTAAATAAGGCTGAAAAATTAAGCTTTCAGCATTAAGATTATTAATTGCAGATTCCAAAGATGAGACTAACTCTAATGGTAAATCAGCAGAAAAGATATAGTAATTAATTGATTGAGAAATATGTTGCCATTGTTGATAGTCATCAATATTAAAATTTAAAGAAGAGTCAGGGAAATTAGCTAATAAAGGATCCGACCAATTAATACGTTCTAAAAATTGCCACAAGGTATTGGCTGGAATGACAAAACCAGGGCTAATTGGATAACCTTTATCCATCAGATCTGCTAAATAAAAAGCTTTTTCTCCTACTATGTTCCAGTCTGATGATTTAATTTGATCTAGCCAGTAAAACTTATACACAAAACTATTACTTTGCTTACGTCATTTTAATTATTATAGTTATCAGCTATCAGTTATCAGTACCGAGCAATTTCAGCCAAAGACTTGATTTTTTTTCATTCCCTTAAAATGGATATCTGATAGCTGATGGCTGAATGCTTATTATTAACATAAAATAATATTAGAAATATTATATCTTTTCAAGGTTCTTGACAATGATTAAATTTATCCGGAGAAAAATTTTTAAACCATTTTTGAATATACTTCTTAAAGCTAACTGTCCTCTTTGTCAGCGTTCAGCAGACAGAGAGTTTTGTCAGTATTGCGAAAAACAAGTTTGGCACTGTCAGTTTCCTGGTGGAGGAGAAATATTTTCTGGAGAAGTACCTATATTTGTTTGGGGTCAATATAAAGATAGTCTCAAACGAGCGATCGCTGCCATGAAATATGAAGATCACCCAGAAATAGCAAAACCCCTGGGATATTGGTTGGCGGATGGATGGTTAGCTACAGCACCCCGTGAAAAAGCGGTGGTTATACCCATTCCTATGCACAAAAAAAAGCAGAGGGAACGAGGTTTTAATCAATCTGAACTATTGGCCAATAGTTTTTGTGAGGCGACAGGTTTACAGATATGGCGAAATGCTTTGGTAAAACTGAAACAGACTCAGCCATTATATAATTTGTCTTCTCAGGAGAGGCTAGAGATGGTAAAGGATATTTTTGCGATAGGCAAAGATTTCCGTAATCGGAGTTCCTATGCTCCAGTTTTACTGGTGGATGATATTTATACAACTGGTGCAACGGTGAATTCTGCTATAGAGGTTTTGCGTAAAGCTGGTATTAAAGTCGTGGGAGTATTGGCGATCGCGACTACAAAAGAACCTACTGCGAAGAAACCACTATTAAAAAGTAAAAAAGTTGTGAAAAAAATCTACTTCTCAAAAGTAGAAATGAAACTCAAAAATATAGTAAGTCAGTAACAGTTTTTTGTGATACTACTTATTCCGAGTAAGTAGGTAGGCGTGAAAAAACTTAGCTATATTAAGATTTATGTACTGACTTCAAGCTCTTCCACACAATTGATTTGAGGCGAATTTAGATTTTGTTATATAGCGACAAAATTCATACTGACCTACTTAAAGTATGATATGATATAAATAGTATATTTTTTATCCAAAATATATCTCTCCAAAAATGTCTATTTGGAAATAGCGGGGCAAGGGCTTGAGAACCTTTTCTAGAGATTTTTTTAGGAGAATAAAAACTGAATTGCTAGCTTACAAAAACTATTGAAAGGGACATCAAACATCAAATATTGTAATCACAATTATTATTAGAGCCCTATTCTTTTGTTACCCTTAGTATTATATCAAATGCGATAGTATCGGTATAAATAAAGTATAGAAATCGGGAACAATATCTAGCAAAGGCTGAAAAAATTTCCCCTCATAGTTGGGCTAGACTTTAAACCAAATTTTTCAGTTTTAGGAACAAGGGAAGTAAACTTAGAAATTTTAGGCCAACCTTTACGGGAAATGGGAATTAATCCAGATGATTGAATAAATTTATTCTTACTAATAAAATGGGACTAATATCGATATACATTGAATTTTTCAAAATACACAAATTTGCTTTAAAATTTTATTAATAACTGTTACAAATTTATTAAAAACTAATACTGTTTGAGATTTTTATGATTAACTTATATTTTTTGTTAAAAATAAAATAATACTTCAACTGTATTAAAAGCATTTAATAATTTGGGCAACAACTAAATATCGTAATTGTCAATAAAAAACTTTTATAGTTTTAAATTATGGAATGGCAAGAAAATTCTGGTAATTGGGTATTAATACCCTCTCGTCCCAAAGCAATCATACATTTTTTGGGTGGAGCATTTGTTGCAACAGCACCCCATGTTACTTATCGGTGTTTACTAGAGATTCTAGCAAATCAAGGCTATGCAGTAATAGCTACTCCTTTTATCAATACTTTAGACCATTTAGCAATAGCTAACAACGTTCTCAGTAGTTTTGAGAATTGCCTAAATCACTTATATACTAGTGAAATACTCAGGAAAAAATCTTTACCTATCTATGGAATTGGGCATAGTATGGGATGTAAGTTACATTTACTCATGGGCAGTTTAAACTCTATAGCAAGAGCTGGTAATATTCTCATATCTTTCAACAATTTTGGAGCTCGTAATGCTATTCCCATGGTCGAACAAATATCTTCTGTAGTGAAAGTAGAGTTTACTCCATCCCCAAAAATTACAAACAGCATAATTCAAAAGCGTTATCAAATTCGGCGCAATTTATTGATTAAATTTAATAATGATAATATAGATCAAACTCTTCGTTTGAGCGATATATTACGACTACGTTTTCCCAGCATGGTAACAGTTCAGAGATTAAATGGAAATCATTTAACGCCCTTAGGTCAAGATTTAAGTTGGTCTGTAGGACAAGTATATACTCCTGTAGATGCTATTGGTCAATGGCTGAAACAAGAGATTTATAAAGACTTCAATAAACTTCAACGTGAAATCCTACTTTGGTTAAATCCACTAGCACCAATATCATAGCTTGATCCTGATAAATTCTAAGTAATCGTATCACAATCGGAACAATTCTTTTGTTATAGGATATATGGCCAATATTGTTTGATTATTAACAAACAGTTACGATTATTAGATGTACAGGTACAACTAATATTATCTGCTATTGCATTAAGTTAATCTTATACCCTGGCCACCATCAACAAAAGAGGTATTGTGAAAATAGTCAAATAATTAATTACTATAGCTATGTTTTAGGGAGCGATGTACTACATTTGCTCCGCTTTTCATGTCGCGCAGCGAAACCTTATTTCCCTATTTCCCTAAAATACTTAACTTTTACTCTAAAAGGGGATTTTTGCACCATAGTGTAATAATCATAGTACATGGCATAAAAGTAAGTATGAGTCAGTCAAAGTCCAAGTCAAAGTCCAAGTACCGTCTTAGCAACTGGTCGGAGTATAATACTTCTTTAAAACAAAGAGGTAGTTTGACATTTAGGCTCACCCTATGAGGTAATAAAGCAGTGGGTCAATAAACACAAAAGTTGACCTAGAAGAGCATCTAACAATACAAGTGATTTGATAATTGAATTAATAGTAACTTTGAGTTGTTTATTTGGACTACCAGGGCGACAAACGCAAAGGTTTATAGAATCCGTATTTCAAGTTGATGGGATTAGATTTACCTGTGCTAGATTATATCACTGTATCCCGTAGAGTCCCCGAAATTAAATATTGCGTACAGCGTGATGCCAACTACATAAGATATTCATTTTTTAGTAGATTCTACAGGGGTCAAAGTTTACACCTGAAGGAGAATGGAAAACTACGATTCACCGTTTTTGGTAAAGGTAGAACATGGGGTAAATTACATCTAGGTTTGAATATTTGCGCAGCATCTGAGGAATGCTGCAGAAAAGATTATCACAGCAATAGCTACAACTAATAATGTTGCTGACGAGCAAGTATGAGGGTGATCTAGAGTGAGGTTGATAAAGATGATATTGTCCAAGTATCAGCCGATGGAGCAAAATATCAATATAAGTGTGATGAAAAAGCTAGTCAGTTGGGGGCAAAATCAATAATTCCTCTATGAAAAGATGGGGTTATTTGGCAGCATGGTAATTGTCAAGAAACTCCTCATTCTAGGAATGAAAACTTGAGGCAGGTTTTGGCAAGTGGGACGAGCATGGATGGAAACAGGAAAGTGGTTACTATCGACTCTCTCTATCTCAAACTAATATGTAAGGACTAAAAACGATATTTCGAGGGAAGTTACGACGACGAAAACAGAGATGCTCAAGTAGTGGAATGATTTGTAAAATGTACAAAGCGAATTATTCAAAGAGGTAAACCTGAAGGTTACATGGGTTAAGTCTAATTACTTCTAATAGGGGAGTAGTTTACGATCGCTACCTTCATCCAAGAAAGCTCTTTGGTAGTTGAGCGATAGCCACAAATTAGTTGCGATCGCGAAGTTAATTTTATACTTAATTTTAATGTAACAATATTTTCTGAAATTCGTATAAGTTTCAATATTTTTTTTCTGAGAGTGAGAAAATAAGCTTTTATTTTAGAAACAGAAATTATATTTTTAATAATTGATAAAAATTTAATCTTAGCAAAATCAAGAAGTTCTTATTTTGACTTTAGCGATCGCCTATGAGATACTATTTTACCTATTTAATTATTACTGTTACTGTACCTGACAAGGATACGAAGGTGCTGTAATTTCAATCAAAGTAAACGGGTACTGTTAGTTTTAGACCAAGTAAGATGGTATATGACTAACAAGTTGGTATTACCTGAAAGTATTGACCTGTTTTTTCTCCCGAGTCACTCCCACCTAGTTGCCACCAGCATAATGTTTGTGGCCTTTGACCAATGAATCTATAGATCGATCTTTTGCTTCGGCATAGAACAACTAACATCCGAGGGTTCGCCAACCATTCACCAGAAAACTTAGATGAATTAGAATAGCTATTGATCTATCGCTGTCAAAAAATTATGGATCAGCATAAATTTCCAGGAATGGTTAACCTGTTTTAACCCTTTGTCTCAAACTAGTAATGTTGAATCATTACTAATCATCCGGACATGATATTACTCAACAAAATTATTTACCTATTTGAATTATTTGTACTTTTGAGAAGGGGAAGAATTCAGCTTATATGGGTGCGTAATTAATTTTGTATTATCCCTTGTCATGTTACCATATTTTTCCTTTTCTATTTGCTGATAACTAAAAATAATTTACATTAAATTTGAAGCACCGTTAGCAGAATTTTAAGCTGGCAGTTGCCACACAGATATAATTCATATTTTTTATATCGGTACGTCGAAATATTTTAGTAATTAATCTCAAAAAATCATAATTTATATAGGCTTATAAATAAACATATATTACTACTAACATTAACAATAAACATTTCGATATCTTTAATATAATAGACTTTTTTATGCACGCCCTAATTATTTAAATTTAGTAGCTTTTCCTGAGTTATGAGAGCTTTTTTGACTCAAATTAGCAACTTTTAAAGTATACAAACTTGCTTCTGGAGTTATATATAAGGGAGTTCCCTGCAACAAATATTCAATTACCATTTTCGTATCTTTAGCAAATAAACCACGCCTAGCACCTACTTCTATAGTTTGTATTTTTTCTCCCTGCAATAGTTGACCTTGTTGGGGAGTAAAAATTAATTTACCTTTTTCACCGTAAAGAGTAAAGGTATTTTCTGAATGCCAAAAAGTTTCACCTTTGCCATAGACAACTTCCCCAATTACATTATTATTAAACCTTAACTGAGCAGTACACAAACAGGCTTTATAAAGGTCAACTTCTGTATACCAAAACTGACTTTGACAATTAACGGTATCAACCTGACCAAATAGGTCGGTAAACCGATGGAAACGAGATAGTGCTCCTACAAAAGGAAAGCCAAATAGTGAATAGCGATAAGTCCATTTTTGGGAGGCAGGTTGTTTAGAATTAATTGTGACGTAACGGGCATAGAAAATTTTACCAATTTTGGACAAAGATTCTTTAATAGTATTGTGGAGACCACCGAGAAGTTCTATATGTTCAACGTGTAATAGTTTATTTTTCTTCTTTGCTAGAGTAATTAATGACTCGGCTTCAGTTGGGTCTAGAGAGAGAGGATATTCAACTATAATATGTTTGTTATTTTCCAGAGCTGCAAGCGCGATCGCTCCATGATCTCTATTAATAGTAGAAATGATGACTAGATCCAAATCTTTTCGTTCTACCAGTTGTTGCCAAGAGGCTGCACTTTCAACTTGAAAGGTTTGACTAAACGCTTCGGTTTTTTCTGGGGTATGACCTGCAACAGTTACTAGGAGGGAGCGCTCATCCGCTTTTAATGTCTCAGCTCTAGCCTTGGCAGCATAACCAGTGCCAACAATACCAACTCTAATTGGGATAGAGCAGAAAGAGGAAGAGATATTTATTTGAGTCATACCAAAATATAGAATTACACAATCTTATATTATAAACTATATATTTAATATTTATGACATATTTAATTTTTTTTATACATATAAATTAAAATAATGGCCAATTATGTATAAGTAATCAGAATTAAATTAGAATTATTTATAACAAATTCTATGGTAATTTTTCTCTCAATGGGTTTTACAACTTTGCTTTTTTCCCTTAATATCAGAGATAGAAAAAAAACAAGTGCAAATACTTTGGTTAATTTAGCCTAGTAATTTGTATAAGTTTAAATTATAACTTGAAATTCTTATTGGAGGAAGATTTAATGGCTACTTACAAAGTTACTTTAAAAACGCCAGACGGTGACCAAGTAATTGACTGCCCTGAGGATGAGATTATTCTTGACATTGCAGAAGATCAAGGCTTCGATTTACCCTACTCCTGCCGAGCTGGTGCTTGTTCTAGCTGTGCTGGTAAAGTAGAGTCTGGAACAGTAGATCAAGATGACCAGTCTTTTTTAGACGACGATCAAGTAAAAGAGGGATGGGTACTAACTTGTGTAGCTAAACCAACATCAGATTGTACTATTAACACTCATCAGGAAGATAATCTGTAGTTGTTAACTACTGTAGAAAATTGTCGAATTTGGTTGATATCCACAAGAGTCTAAAAAATAATTTGTCAGTCTTAATATTTTTAGATTTTCGGCTCTGGCAAAAAATAAAATTATTTGATGAAAAAATAGAAAAGGATAGACAAATTTTTAGACATTTAACTAGTGGAAACTAATAAAAAAGTAATTCTCACATCTAGGAAAATTTATGTGAGAATTTTTGCTTATCTTGAATACTCTTGATACTTAGTTATTTTTTTCAAGAAAATCGGCAAAAAAGTTAATTTGAGCAATTTTCTACAGTTGAGTTAATACAGTAGTTTATCAAAACAAATAAATTTTTTTTTGTCAATAATTTAGGGATGGCTGAGCTTAAATAGACTCTTAAGGCACCACAACTAACAAAGAAGAAAAACTTTAATTAAAGACTTTAGTTGGCAACTTCAAATCAATCAATCTACCAAATAAATTTTGAGAGGAAAATAACATGGCTACATACAAAGTTACTCTGATTAATGAAGAAGAAGGAATTAACCAAACTTTTGATTGTCCAGATGATGAGTATATTCTTGATGCAGCAGAAGAACAAGGCTTAGATTTACCCTACTCCTGTCGTGCAGGTGCTTGTTCTAGTTGTACTGGTAAAATAGAGTCTGGAACAATAGATCAAGCAGACCAATCTTTCTTAGATGATGACCAGATGACAGCAGGATATATATTAACTTGTGTAGCTTATCCTACTTCTGATTGTACTATTCGAACTCATCAAGAAGAAGGAATTGCATCATAGAATTGAGTTGACAACCTCAAGTCAATCAATTTACCAATAGCCTGGTTCTTGCCCATTAATTTCTGTAAGCGCCGAAAACAAGGACAACATAAGTAATAAAAGTGTTTACAATATTTTCTTGTTGTCAACTTTGGTTGATACCCCCTCAGTAGATAACTTTCTACTTTGCATTGTTAACAAGTTTTAGCACTCATAGTATCCGAAATTATCTAAGGACGAAAATATTAAACCTATCCAAAAATAGATATTTTGGAGAGTTAGCATAAAGGTTTGACAACCTTTTGTTCAAAAAGTTTATTCAATAAAGGAGCACAACATGCCAAATTACAAAGTCACTTTAAAAACTCCAGATGGAAATAGCACAATTATTGAAGTTCCTGATGATCAGTATATTCTTGAAGAAGCAGAAGAGCAAGGCTTAGATTTACCCTTCTCCTGTCGTGCAGGTGCTTGTTCTACTTGTGCTGGTAAAGTAGTGTCTGGAAAAGTAGACCAATCAGATCAATCTTTCTTAGATGATGACCAGATGGCAGCAGGATATGTATTAACTTGTGTAGCTTATCCTACTTCTGATTGTATTATTGAAACTCACAAAGAAGAAGCACTTTACTAAAGACTTGAGTTGACAACTTCAAGTCAATCAATTTACCAATTTTGAGAGTAACTTTATATGGCTACATATAAAGCTACTCTGATGAATAAAAGATAAGGAGTTCATCAAACTATTGATTATCCTAGTGATAAATATATTTTTGATATTGCCACACAACAAACTCTAGAACTGCTCTATTCCTTTCGTGTAAATGCTAGTCCAGTTGTACCAGTCAAATTAAATTAGGCTCAGTAGACCAGCCTGATAAATCTAAATCTTTCTGAGATAAAGATCAGGTGGCCATGTTGGTAGTTTACAAGATTTACCTACTGATATCAAACCATAGACTAGATGTAGAGGTGAAAAGCCGTGTATGAACCACAATATATTTGCCTAGTACTCGGCAATAAAACACTCCTGCTAGATAAGACAGTTCTGGATAAGCTCTGTTATCAGTTATCTTAGAATGTATGACAATTTAGGATTTTTTAATTGTTTTCTAATTGATTAGAATTAACGATAAACAGCTAATCTATTTACCCAACTATAGCTATAACTATCTATTTTTTTCCAAAATTAGCTAACTTACTAAGAGTTTGGACTTCAGTTCCCGGAAAATAAAAACTGAGAATGCGATCGCTACTCCAACCTAACTCAGCTAACTTAATTGAACCTTTCTGACTCAAGCCTACTCCATGTCCAAAACCACCGCCAACAAAAGCGTAACCCCACAAAGTTTTATCGGGTTTGTATATAGAGTCTAGATAAAACAGTGTGCTCCAAGGGACCCAAAAAGCATTTTGTACCTCGTCTTTATTTAACTCTATAATTCCTCTATCTGTTTCCACAGTCATTTTCAGAACACGACCAGCTAGCGATCGCTTCGTCACCGCTACTTTTTTAATAGTATTAAACTGAGCAAAAGGACTTTTTTTCCTTTGAAAATAACCCCTTAAATAACCAGATATATCCGGTAAACTAACCACCTCCCGCCAGCGAAATTCTCTCCAACCATCTTCATTAAATCCTTTTTTAATACTCATAAACTTACGGAAATTTTGATCAGTTGCTAAACTATTTTTAGATATATCCCAAATATTATTAGTAGCATCAACAACAGGTATTAAATAAGGACGTTTAGTACCATTCCACAAATCATTAAAAGCTGCAGTAACACCACCACTAACAGCAAAATAAACTGCATCTATCAACTCATCTTTATAAGTCAAAACTTTTCCCCTAGTTGCTGTTACTGCCGCATCTGTTTCTGGGTAGACATCTAATCCTTTATAAACCTGACAGTGAGTATTAGCACATAACTCATAATTATCTACCATAAACCGATGTAAATTTTTCAGTGCATAAGTTCTAGCTAAAATTGATTGAGCTTCTAGGGATGCTTTTGGTGGCCAAGCCCCTAATTCATGGGGTACTACTCCCCGAATGTAAGTTTCTATTGGTACATTATTAACTAATGTATAAGTACCATAAGCATTAGGTTGTAGTTTTAACGAGCCTACATAACGTCGTTCTTCTAGTGTTGCTCTGTCTTGGTTAAATTGATTATTGATGATAACTTCATTTTTCCCCGCAGTAATATATAGTTCATGGCGATGATAAATATAGCCATTCATACTCCAGTAAGCTGTAGGCCTTTGTTTTAAAGCTTCCAGCTCAAGATAGATATTTGTATTATTATTAGCTTGTAGACTTTCTAATAGCCAGCGTCGTAATAAAGGAGTTTTATATACTTCTCTTTTTCCCCAAACTTTCCATCTACCTGGTTGAGCTACTTCTACTTCTATTCCTTTCTTTTTCCATAACTGGGCATCTTCTTCAGCATTTTCATAACTACGGTGACTACTAAGAATTAATCGCTCTTTTAAAAGAGGTTTTTTTAGAGGTTTAACTTTAATTTTTAGTTCTACTTTTTCAGTAGTAAGAGTTTCTTCTCCTGCAGGAGTTTTAAACCGCAAAGTCAATTTATCTCCTGGAGTAGCTTTAATAATAATTTTATCTTTTGGTTTAGCACCAAATCTTTGTATAATTCCTATTTTGAGTAATCTGTTATATTCTTCTACGGCTTTGACTGGTGTTATATTTAATCCTAGTAACAAAGCTGTTATAAAAATTGTATTTTTGATGATTTTTTGAGATTTTTTTGCCAACAATTTTATTCACCTATGTAGTATTTATTTGATAATTATTTTACATCAAAATGAGTATATATAAAAAACTATCAAATAAAAAAATAATTTTTATAAAAAAAATTTTTATCTTTTTTCTTGATGTTTTAATCTCAAATATATTAATATAGAAATTATATTTTAATTTGTCTTCAAAATTTTCTCATTTTTTGGAGATATGCAATCGAAATTAGTTCAATTATCAAGAGTTTCGGAGTTTATTTCTAGCTTTTGAATTCTCACAAATATTTGATATGATTAATGTATTATAATCCTCACAGAGTAACAAGCCAGATGAAAGCTATATATTATAGAGAATAAACTGAAAAATATTTCAAGTGAAAAATAAAAATGATTAAGAATCAATAGGGATGTAGTGGTAGTAATGCACCCCTCCCCTTTGAGTAATTTTTTTATTCACTGAAGCAAGTTTTAAAACAGTTAAAGACTAATTAGTAATTACAAATAAAAATTATTAAAATTGAATAGATTAGCTTTGACTACATTCTAGTTTTATTTATTTAAAAAAAATATTATCAAAAAAAGAATAGAATTTTGATTAATACCAACCTAACAATTATGATGAATTTTAGATACAAATTATCAGCCAAATACTAAAACAGTAATAATTAGCTTAGGGAATAAAGTATATATTTAATAAATAACAATAAAAAGAATATTTTTAATAATCATAAAACCTAGTAAATTGACACAAAAAAAATAGTGATTAGTCCTATATTAATATTATTGAAAGGCAAGAAAATAATTAATTATAATGGCAGATAGATAGTGACCAATTATTTTCCTATCCCATTGCTAGTAAAAATATTAACAATAAGATGTATCTATTGTTTTGATACCAAAAAATTAACCACAACTAAAGGAGGTATAAAACTAATAAATTAGGAATGTATGATTTTTTGATATACAAAAAATATAAAAACCATTTTGTACCTTTGCCCGCGATTAAATTTTTAAGGCATGGAGTCATATTTGGGAAAAAGCAAATCAATACAAAAAGAGATTTAACAAACCAAGGCAATACTCTCTTCAGGCACCAAGGCACTGAATAATTATCCTGTCGCCGAAGGCACAAGCCTTCTGAAGATCTTAAAAAATAGGGATTAAGATCATCCCATACAGCAACTCCAGTGGAGTTGGTATTCCCAGCAGAGGTCTTAAGGGTCACCTTCTACATAACTACCTTCTACATCCTGCCTTCTCAAAAATACTCCAGCATACCCCATCTCCCCATCTCTCCTTAATCTTTTAAATAAATACCAAATGGATTATATACTACAAATAGTTAGCAGTTATGGTATATTTTAGGATATACAAAAAAGTTTGCTCTTTTCCGTATTTTACTGGCAGGATGAATCAATCTTTTCGAATCAACTACGCCCCAATATTACAGAACTTAATGCAAGATGCAAATATTTCCAGCTATAGGGAATTAAGTCAAAAAGCTAGAGTTTCTGAGTTACAAGTTATTCGGTTGCAAGGTGGGCTAGCATCACAAATGCGAGTAGATATTTTACTCAAAATAAGTCTGGCATTAGGAATAACTTTAACAGAACTATTAACTAATTTTGCACCTGAACTTGTTAAAAATTTACCGAAAAATTCCACTTCAGCACTAGAACAAGAATGTAAAAATCTCCAAAAAGAATTAGAGCAACAAAAACAATTTTTAATGCAAGAGTTTCAGCAGTCTAGTTTACAAATTTTAGAATCTTGGCTACAACAATGGCCTACCGTGATCTATAAAGCTAAACAAAATCCTAGTTTAGCAGCCATCAAAATATTACCTTTGTTACGTCCAGTAGAAAAACTGATGGGACAGTGGAATGTTGAATCTCTTGCTCCTGTGGGGGCAGAAGTTCCTTTTGACCCGCAGTTGCATCAACTAATGGAAGGATATGCCCAAAAGGGAGAAATGGTAACAATTCGTTATACTGGCTATAGGCAAGGAGATAAACTGCTGTTTCGTGCCAAAGTTAGTCCTATAAGTTAAATTGGTGTTACTGATGGGTGGCTATGATTTTTGTTAATGGCAATAATAGTGAGTATTCCTATTATGTTTTACGGGTTTCATCTCCCGTAGATATTCATGTCGGTCATAGCTGAAAACTCCTAACTATTAAGTAAAAAGGATTTGATATTTTGCCAAATAATGCTTCAATAGCTTTATTTAGCAATGCCGTCAAATTAAACAACAAAGAAGCTTAGAATTAAGGATTAACTTGGAAATAGCTGGACTTTATTTCAGTAATTACCTATACTGTCTTGAGTATTTTTAATATAAACCTCCACAGAAGGTTTGAAAACCTTTACTCAGCCATTCTAAAATTTGCATTTTGGAAAAGTATAATATTAAAATTTATAGCTTCTAGAAAATATGAATAATCTTGTTATTAAATATATTGAACCCTCTGGTATTATAGATAGTACTAAAACTACTTCATTTCGCCAAGATATTAGTGAACAAGTTAATGCTGGAGCTGATGTTGTTGTGATAGATTTTAAAGAAGTAACTTTTATGGATAGTTCCGGTTTAGGTGCTTTAGTCATAGCACTTAAGACTGTTCGTGCTGCTGGACGTAAGTTAGTTATATGTTCTATTAATGAGCAAATTAAAATGCTTTTTGAACTAACTAGCATAGATCGAGTTTTTCGGATATTTCCTAACCGAGAAGAGTTTAAAAAAGCTACTAATATAAGTCTTCAACCTCAAAGCAAATCCTAATCCTAAAATTTCTAAATAAGTATCTTAGATTTTAGAAAGTATGTAATAGCTTTACATAATGTAGATATATTATATAACTGATGGGCTCGTCAAAATAGAATTAGTTTTTGATTAATGGTTCAGCTATCCTGAAACCCACTAAAATTTAATATATTTGGGAGCAATAACGGTCAGTTATATAATCTTATCTCACGGGCTGAAGCAAAGCTCTGCTGACGGGCTAGATACTTTACCTCCTATCTATAGTTTATTGTTTATTCAATAAACAAATAAAAGTTAAAAATATGATCAAAAAGGGTTGATATTTATAAGTAAAAATAAATAAAAGTGAGTATATTAGGGTTTTATCAATACCTTATGGAATAATAATTGAGTCTATTTTAAGTAGTTAAAAATATGTTCAAAAAGGGTGTGATAAAAAAAATCCACAAAAATCATAGGAAATAAAATTATTAAATCTACTATGATTTATTAATTTTATCTAATTCTATAAATTTAATTTTAACCTAAAGTACTACAACAATTAAGCATTGGTGAAGTTAAGAGAATAATTTTAATTTCAATTGCTATTTCTTGTGTCCATAAAAATATTTTAGGCATCGCTTACTATTGAATTCAAGCTATTCCTAATACTAGATACTGGATAATTTTTCCGGTTTCAAATATTACCAAAAATATCACGCTGATTACATAAAAAATGATTGCTAAAATAAGTCATTCTATTTTGAGATATAATATTTTATTTATCGACTAAATTTACATAGTCTAATCACTCAATTTTTAGCTAAATTATTCAGATTATTCCTCAGAAAACTAGGATTTTTTTATAGTTTTAATATAATTCTAATTTTAGTGGTACCTCTGAATAGATTAAATCAATTTGTGAGAAACCCTGGTTAAGAAGTTACAGACTATTGGCCAAAGTGTGATGAATCTCACCTGAATACTTACTTTTCCTGAATTGTAATTCATTTTATCCTTAATACTCAAATAATTTCAAGATACATAGGCAGTCTAACTAAAGATAAGTTTTAGCAAAGAAAAATCATCACTAAATACATCACTACAATTTAGCTTTTGTATATAGTCTAATATTTTGTTTATATCGCAATAACCATATCTATAATATTCTAAAATTAGATTAATAAAATTATCTATTCCCCAAATTTCTCCGTCAGATAAATAAATTTCGTAAACACCATCACTAAATATATATAGAGAGCTAGACTTTTCTACTATGCAAGAATCATCTATATAAGTAGCCTCTGGAAACATACCAATAGGCATTCCAGGAGTTCTCAATTTACTTACTTGAGCAAGGTGACTATCACCAGAGATCAAAATAGCTGGGGGATGACCAGCACTTGCATAAACTAATTGACTTTCAGAGAGATTATATACACCATACCAAATAGTAAAGTATTTATCATTTTGAGAGGTTATTTGGTAAGTATTATTTAAAGCTCTAAGTACATCACTAGGTTTATAGTAATCTAAGTTAGGTATGGCCTTTGACCTCAACAAATTCAAAACTGAAACTGAAGGAAGTGCAGCTCGTAAACCATGACCTGCGACATCTAATAAATATACAGCTAAGTAATTTTCATCTAACCAATAATAATCAAAGCAGTCTCCTCCTAACTTGCGACAAGGAATAAACTGAGATTCAACTTTTACTGGTTCTGTTACAGATGCTGGTAGAAGAGAAGACACATAGTTCGCAGCCTCAGCTAATTCTGCTTCTAGTAGTTGCTTTTGGGTCTGCAAGTCTTGAGAAAGCTGATGTAGTCGGAGTCCAGCTCTGACCCTAGCCTTCATTTCATTGATGTTTATAGGTTTGGAAATAAAGTCATCAGCACCAGCATCAAGACCTTTAACTAAATCTTGAACACTTCCTAAAGAAGTTAACAAAATGAAGAAAGTAGTGGACAAATCAGAACTAGCTTTAACCTTACGGCATACTTCTATTCCTGTGAGCCGCGGCATGATCCAGTCACAGATAATTAAAGCAGGTTGTAGGAGTTGGGCTTGTTTAAAACCTTCTTCACCGTTACTTGCTACTGTGACAGTATAACCCTGTTTGCCTAGAACTCTTCTAAGCAATTCCTGAACTGTAGTATCATCATCAATAACCAAAATTTTATATATCATGGACTTAGTTAAACAATTAATTCACTGTTTCGGCTAAAGATGACATAAAAGTAAGTAGACCAGCAGCTGGAATTTATAATGTTAATTATTTACATAAATTCTATATAGATCAATTATAATATAGAAAATATACCTGATACATTATGTAATTATTGAATATAGAAGTGTGGCTACCGTAAAACGTTCTGATAGATTACCAATGCTTCGTAAAGCTTATTTGCAGGTTTGTTCAGACCTGAAAGAAAATGAGAAAGTTTTGTCATGGTTTGAGCAATTGTATCAAGTAACAATTCCACAAACAATTTGGTTACAGTGTGAATTGACTTTAGCTGAAGGTTTCACTAATGCAACTCGCCATGCTCATAAGTATTTGCCTAGAGAGACACCTATAGATATTGAAATTACAATGTATACCAACTACCTCCAAATTAGAATTTGGGATTATGGTCAGCCTTTTGATTTGATAGAATGGTTAAAGGCACAACCCGATCCAGATATATTTGCTTCCGGTGGACGAGGTATAAGATTAATGTATGCCATAGCAGATCATATTAGTTATACTCGTACATCTGATAATCGTAACTGTTTGTTAATAAGCAAAGATTATTGGTGATATCCCCAAGTTTAAATGGCAATTCTGATTTTGAGAGAATCTGAGCTTTATTAGTTACTCTAAGAAATATTTAGGCTAGATACTCATAAATTAAGTATAGAGAATAATAACTATCTGCATTTTTGTTAAATGATGAATAGGTGCATTTATCATTTACTATGAATTTCTTCCTTCGGGTCTTTTGACTGTCTTTTCTTAATTAAAGTTAATGTCTTCTCCTCTACTATAAGTTTTCACTGATTGGCTATCAGACACTCCCTGCACTAAGTTGGACATTAGGTCTGGCTTTGAGACCCACTCTTACTCTCAATTACTCTTTGAGTCTCTGCTATTTACCATCCAAGTAGCTGGCCTAAACATAAGTGTAGATACTCTGCCATCGTGACAGGCCATAGCATTACTCGCCACTTGATTTCTTTTGTCATCAAGTATCAAATTAAATTGATAAGGTTGGCTTTGTTGCACTGCGGATGCCCATAGTGTAAAAATAATAGTACATGGCATAAAAGTAAGTATGAGTAAGTCCAAGTCCAAGTCCAAATCAAAGTCTAAGTAATGTCTTAGCAACTGTTCTAAGTATAATATTTCCTTAAAACAAAGAGTTAGTTTGACATTTGGGCTAACCCTATGAGGTAATAAAGCAATGGGTCAATCAACACAAGAGTGGGGGGTAGAGGAGCATCTAATAATACAAGTGATTTGATAATTAAATTAATAGTAACTTTGAGTTGTTTATTTGGACTACCAAGGCAATAAACACAAGGGTTTATAGAATTTAGATTTCACTTGATGGGGTTAGATTTACCTGTGCCTGATGATAGCACTGTATCCAGTAAGCTCAATAAATTAAATATTGTGTACAGCGTGATCCCAATCACGAAAGGGATTCATTTGGTAGTAGATTTTACAGGGGTCAAATTTACGGTGAAGGAAAATGGAAAACTTGCATAATTTTAATGGCTAGAAAATAGTGATATAAATGCTATTGTATATTGCTACACTCACAAAATAAGGAATAGGGAAGGTCGATATACCAAAATCGAAAAAAAAGGCTGAAACTTAAGAGTATATGCCAGATACCAACTAGGTAACTATAGGTATAAACTATGCATTAAGATGTCAAACCTAGGAGTAAATTAGGGTAAAAATTCCTGCCTTTAATAAAGCTTTTAAAATGATATAGTTGTTTTAATTAAGATTGAGACAAAAATTGAGTAGAATAATTTTAATTCAACTAAAAACTATTTTTCACCATGCCTTACAGTTTAGACTTCAGGCAAAAAGTCATAAATTTTGTAGAAAATGGTGGTACGATGACCGAAGCAGCTCATTTATTTGAAATAGAAAGAGCTTCGATATATAGATGGTTATCTCGCCCAAAATTGTCAGCAACTAAGGTACAATGTCGTCGAACAAAATTAGGTTGGAAAGAATTAGAAAAAGATTTAAAGCCAAATCCAGAGTTTAAATTGGTAGACAGAGCTAAAAAATTTGGAGTTAATCAAGCAGCTATATTTTATGCTTTGAAAAGAATTAATTTTCCTTAAAAAAACAACAACTTCGTTATAGGGAAAGAAATAGAGAATAAATGATAAAATATTATCAGCTTTCCCTCGAAATTTCATCAAAAAATTTGGAAGTAAAAGCCTTGTATTTATTTATGAATCAGAATTTGAAGAGAATCAAGACTGTATTTATGCCTGGTCAAAAAAAGGGAAAAAAGTTTATCTTGAGCAAGAGGGAAAACGAGATAAAAGAAAAAATTTAGTAGCCGGGATAAGAAAAAAGGAAAAAGATTTAATAGCACCAATTATATTGAAAGGAACCCTAAATGCTGTGGTATTTGAACAATGGTTAGAGCAACATTTATTACCATCATTAAAAATTCCCAGTGTACTGCTGCACGGATAATTAACCATTAATTACGGAAAAAGGTTATTAGAGAATTAGTAGAAGCAGGGGGTCATCAATTACTATTTTTGCCAAAATACTCTCCTGATTTAAATGAGATAGAACATGATTTTAGTGCATTAAAAAAGAGCTAGAATGTATTCATCTATCAATACATCTCTTGATGAAATTATTCGTAATTATTGTTACAAATAGTGTCTCATTCTTATCTATAGTTTATTGTTTATTCAATAAACAAATAAAAGTTAAAAATATGATCAAAAAGGGTTGATAGTTATAAGTAAAAATAAATAAAAGTGAGTATATTAGGGTTTTATCAATACCTTATGGAATAATAATTGAGTCTATTTTAAGTAGTTAAAAATATGTTCAAAAAGGGTGTGATAAAAAAAATCCACAAAAATCATAGGAAATAAAATTATTAAATCTACTATGATTTATTAATTTTATCTAATTCTATAAATTTAATTTTAACCTAAAGTACTACAACAATTAAGCATTGGTGAAGTTAAGAGAATAATTTTAATTTCAATTGCTATTTCTTGTGTCCATAAAAATATTTTAGGCATCGCTTACTATTGAATTCAAGCTATTCCTAATACTAGATACTGGATAATTTTTCTGGTTTCAAATATTACCAAAAATATCACACTGATTACATAAAAAATGATTGCTAAAATAAGTCATTCTATTTTGAGATATAATATTTTATTTATCGACTAAATTTACATAGTCTAATCACTCAATTTTTAGCTAAATTATTCAGATTATTCCTCAGAAAACTAGGATTTTTTTATAGTTTTAATATAATTCTAATTTTAGTGGTACCTCTGAGTAGATTAAATCAATTTGTGAGAAACCCTGGTTAAGAAGTTACAGACTATTGGTCAAAGTGTGATGACTCTCACCTGAATACTTACTCTTCCTGAATTGTAATTCATTTTATCCTTAATACTCAAATAATTTCAAGATACATAGGCAGTCTAACTAAAGATAAGTTTTAGCAAAGAAAAATCATCACTAAATACATCACTACTTAAAAATAACTATATATTATTCTCCACAAGAATCAATTGTTTGTGCAGTTAATTCTGTAATTATAGATATCAACCTTTTCCTGAGCTGCTCTAAATTATCAAATATTTCCCATGTTAATTTTATGTTTATTTCTAACCATAATCTTTCGATAGGGTTTAATTCTGGAGAATAAGGAGGTTAAAATCAAAAAATTATGTTCTCAGGAATTGGCATATTTAAACTTTGATTTAGAGCTCCATTGTCTAATTGAATAATATGTAAATCATCAGGATATTTTTCGGCAAATAACTCCAAATATTTTTCCATACACACTGTGTCTAAATGGCTAAATTAATAGAAAAAACTCTCTCCTGTTAATGCTTCTATTGAATGGTTATATTACTCCCATAAAGCGACAAATGCTTAAACAGCCATTGGTGTTTCCCTATGGACTTAATACTCATTCCTGTTAATAATTGACCATTGATAGTTTTCAGGCAAATTCTTGTTTCGTCTTCACATCAATATCTAATTTTCTCAGCTCTTAATTTTTTTTCCTTAGTTGTTATTTTTTTTTTAAGATTTTCTTTATCTAGTTTTTTTTAAACTCTTCAAATTCTTCTAAATTTGTGGTACTTTCAGTTGACTTTTCAGCCGATATCTAAACAATTCATATACTGTTAATTATTGAACTTTGTTTTCATAAAACACTTGCAGCCATTATTGAAATTGACCATAGCTAAAGAAACCTTCCACAGATATGAGTGAGTTCTTTGGTTATTCTTGTGACGATCTCTGATGGTCCTGCTCTTGGCCTTCCAGGACTTTTTTTGTGTTTAATATTCCTTCTATTTCCCCTTGACGATATTCACCAAACCAAGGTTATACTGTAACTTGATAACAACCGAGCAAGTCTGCTATTTATCCTATAGTAAAAAGCTTTTTCGTTTTTAACCAGTAAAGTGCTTGTAATTTTTCTTTGATACGGCTATCTGTTTGATAGGACAAAAGTTTTTTTAAATTCAGATTCTGTTTCTAATATTTGAGTTTTTGTTCTCATCTGATAACTGCAATCACTTAATAATTTTATAACTATTTTATTGTAACAATCTTTTTGGAAATTAGTATTATTTGAATCACAAAAAGCTCAAGAAAGTCAAAATAGCATAAGCCTATAGTAAGTATTGTAACAATCTTTTTGGAAATTAGTATTATTTGAATCACAAAAAGCTCAAGAAAGTCAAAATAGCATAAGCCTGTAGTAAATATAGCGCTTTTTTCATTATGCACTATAGTATATGTATTATCTTTGTGTAAGTCCTGTGTATATAAAATTAAATCACAATTGGGATAAACCCTTCTGTATAAGTTCCTTATGCCTTCTGCCTTCCTTTCACCAAAGTATAAATATTTATCTGGATATGATTAGATCGTCTTTATAGCGGTAGTCTGATAGACATTACCTCTGAGAACCTCTACAGATAAATTATATCTTCAGTTACCAATACTAATCTTTGTTATCTATTCCATGCATCAGATTTTCCCAGCTGCTGCAATTTAATTGCACCTTCAAGACTTTGTCTACTTCTGTAATCTAGTTTAAATGGTAAAACAGCTTAAGGAATAAGTAGACCCACTCTGAATATTTTTCAATCTAACTAATACCAAACTCAACAATCATTTGCTCTACCTGAGCAGCGACCAGAGGGTCTGGGTCATTCCTCAAATGAGGCAATAATTCAACTAATGCCCGTTGAGATGCCATTCGTAAGTAAGCCAGAGCTGCCTCCCGTACAAAACCAGTAGGATGACGTAAACAAACTAAAGTTTGTTCTGCCGTTAAACTCCAACGAGCTGCACGAGCCATCTGTAAACAACAAGCTAAAGCCCACTCAGAAAGAAAATGGCGAAAATCTAGCAGGTGTCGTAAGCGATCGCTAGGAGCCATTGGTTGATAAATCACCATTTCAGATAAACTATTTAATTTTTCTTCATAGCTCTTTTGATCCAAAATATCAATCAGCGATCGCTTACAAGAAATATCTACAGTATTATCCAAAATTTCCAAACCGCGAGCCACATTTGAACGGGAATCTGAGTTAATATTAAGAGCTGCTGCCTTAATAGAACCCAATGGATAAAGAAACTTCATTAACAAAAAACACTGTTCTATAGCATCTAACTCCAACAATTGTAAAGACCGCAACAATATTTCTGTATAATCAGTAGTTAGTTTTCCATTACTTTTCTCTAAAGCACTAGAGAGAGAATTCTCTGAATTAATACTTACCCCAGACAAGTCTACTATACCCGCATAAATCTGTCCCAAGAACATCAACTCTTGCTCTACTAGAATTTCAACTCCACTGCGGCCTACTCGTTCCAGGACCCCTTCAATTCCTATTTCTTCCGGCATTTTCAATAATCTGCGTAGAATATTACGACGTGTTGTACCCCAAGTTGTCATCATTCTATTTACCAGAGAATCTAGTGCTTCTATTGTACCAATTTCACTAATAGCAGTCCAAGCTTGTAATCGAACTAGATCTGACTTATGAGCATCATCGGCTAACTTCACCAACATTGGAATCGCATCATTACCTAATCTTACTAATGCTTGCAATGCAGATTCTCTGGTTGATTTGTAGGATAAACCCCGTAACAGTGAGGGGTAGTAACCTTCCAAATGAGTAGCAGCAATCACATCCATACAATACTTTCGTACTCGTAAGGATTCATCTTGTAATAAACTCGGAATATATAATCGTAACCCTTGCAAATAATCTGCTTCTCCCAAGGCACGAACACCCATGACTCTTTCCTTTTCCAGTTTAGAAGTAATCATCCTGCGTAAAACATTAGTAGCCTCAGCTTTTTGCTCTCTGTCTCCTCTACGCATAATTAAAGCTGCTGCTGTACCTCTTACTACTGGATCTACTGAAGGTTGTAAATAAGGCCGAAGTTGACTAACATCTGATTTTGATTCTGTAAGCCAGATATAACGTAAAGCCAAAGCTAAAACTTGTGCTGGTAGTGATGTTTGAGTTAACGAGCGCACTTGTTGGAGATAAGCTGGATTAGGGTGATTCAACATTACTTCCAAACTTTGAGATTGTAATGCCGGTGACATTACCCCGAGTAGTGGAGCCAATATTTCACCTATATTTTTTTTATCTATTTGACTTAATAACTCAATACAGGAACGCTTATCTTCTTCTGCCGTTCCTCTTTCCAAAGTTTCTACTACTGAGCGTTTCAATGCCCTCATATCTACATCTAAAACAGCAAATCTACCTTTACCTGCACTCCTTACCAATAAGTTTACATATTGAGTTCTAATTAATAATATTACTCCTAACCATACCAGAGCTGATATGATTATTGCGATCACAAAGACTAGACCCTGCTGGTCTGAAAACAAACGTTGATTGGAGTCTAATATTAATCTACTTACCCCAAGAATTGCTAGTATTATTAATCCACTTAAGCCTGTAGAAAAGGGTTCTGCTACCCCATTTACCATTGTTTGAACATCACTACGAATATTCTCTGGTAAAGGTTGGAATAAAACAGGCCCAGTAGTTTCTATTAATGTATAGTGTAGTAACTCATCTAGAAATCTCAGGATTACTAATCCTATAAATACTGAAAGTAATCCTGTTATTGCCCCCGTCAAAGAAAATAACCCTAAAGCTATTGCCCCTAATGGTAGTACCATTGCTGTACCAAAAACTCCTATTCTTTCTACCAGACGACTAGAGGCAAACCATTGAGTTACTACTTGACAAGTACTCAAAATTCCTTCAAACAAACCCAGGAAACTTGCTATTTGATTTGCCCCATTAAGAGACCGGTTTTCCAATTCTAGTTGATAAAAAAATTGAAAGTCTACTAATACATATAGTACCTCTGCTATTACAAAGAATATGATTAACGGCAATATATAACCTTGTAGAGGTCCTTTTACTATCCGAGTAGAAAACTCCTGCTCCTCATCTTCTGGTATCCAACGGCTAGAATCAGGAAAAGATTGTTGATATCTCTCTGATAAATATAACAGTATTCCTGACCCAAATAATACCATTAAGCCCGATACTATTGTAACGTTATTCAGCGACACAAATGATATTATTAGAGGTAAAGAAAATCCACTAATTACTCCTGCTACTAAAAAACCACTACTTATTATTGGATATGTCCGTTTAATTTCTCTAATATTAAATAATTGGTTACCTGTGATTGAACTATTCAAATCGTTAAGTAAGTAACAAGCCTCTACCCATAACCACATCATAAAAGTAGTGAGAAAAGCTAAACTTAGACCAGCTATCTTGATATTCTCAATGCCAATACCAAGTCTAAATAAGAATAAAGGAATTGCCATTAGTAATAAAATTACTACTATTACTCGGCGCAGAGGCATGATTTTTTGTAGCCAGGAGTAGACAAACCCAAGACCTGAACCTATGCCAGCACTAGCAATATATATCCAAGGTAATTTCTCAGCACCATATTGGTCTAAGAATAAACTAACTGTACTCAGTTCTAACCAAATTAACCCTATAGAAGTAAGAGTATATACCACAAACATTAGTAAGGTTCGCTCTACTTCTTCAGAACGGAGATTGAGAGATATTAGCAGTTTATCTCCTAATCCTGTATAACTTTTTAAATTTCTCACTTCCATCTGGTTTACTGAATTTTTACTAAATTATATAGTTAATGAAATATCGTAAACTTTCTATATCAAGATCGTCAAATATTGTCATATATAACAATATATATAAAATTTATTCACCTAAACAAAAAACCTGATTTGATAGGCTTTTAACCTGTATCTACCTTTAATCTTATATTATGTAAGGTCTATAATTTAGCAAAAAACAGGGTCGCCTCGCCTGCCTATTGGGTGGCTTTTTAGTTGTTTTTGGCGACTTTTTAGTTTTTTTTGAATACATCTGTTATTCTTTCATTAATTAGTTAGTCGCGGGCGGGCAGTCATCAGACAAAATATGAACGCACCAGGCCAGGGGTTTAAATAGGTTCAAGCTTTTTGATATAGATTTAAATTGCAGCAAGATAAAAAAACTTAACCCCCATCGGAGTTAAGGCTCACAATAACTCTTTCGTGCCTTATACCCGGGGAAAATGTTAATGTGTTAAGTCTTTTTAAGAATTAGGGATGTTGCATTCAACGTCCTGAGGGTTATTGTTTATTTAATGTGCTTTATTTCACTGAAAACTCTTGTAGTTTAATACTAATTTCACAAACTTAGACTAGACTGCTTATTTTAAAAGATCATAAGATTTTATTCTTGATTATAATGTGTAGCTATTCTTGAGGGAACTGGTATAATAATTGAAGATTACAGCAGTTTCTTTATGGATAGACTATTATGGACAGACTACAATGGGGAGATTCCATGAAACGCTCCTAAAAATTTTTAATTATAACATGAAGTAATTTATTTTTTTTATCAAGGGTGAAGTAGAGCTATCCCCATTAATATGTCCGCGCTACAAAGATTTGAGGATTAATTAAATGTCTATAAGATTTTCCGCTCCAGAAGCGTCAGTAAACAGCATTTAGCAGTCAACTGAAGATTCAAGGGTAATATTCCCCTACTGTATTTAAACAATTAGTGGGCGATATTTAATGAGGTTTTTAACTACTCATTATATAGCTATTGAAGCTGATAGCTGATATATGAGAGCCGATAGCTCAGAGCTAAGATTTAAGTTCTACTTTAATATTTTTTATATTCGCCCCGGCCAAAAAGCACGGTAATTATTACCGAGCCTTGGCTGATACGTGGTTTGACGTCTTAGAGGCGGCTTCTACCTTGGCAGTAGTCTTAGGCTGACCTTCTCGTCCATTTCAAGTCTCGGAATACCCAAGCAGGACTGACAAAAAAATTTTGTAAGTAGGTCTCTATTTGTGCTTTCAGGTTTGAACTGCTCATTGACCTAAAAGCTTCTTAAGTTTAACTCTCAAATGAAGAGGTTTCAAAAAACCTATTCTTTTCTACTCTACAGTATTTATGAGACAATTCGGGTATTTAAACCCTACTTATTAAACAATTAGAAGTTGTCCTAGAAGGGCAAGGCTTTAAACCCAATTTTTCCGTAATTAATATAATTGGTACCTGCTGTAAATTCTATATAAATGCTTAAAGTATTCAACTTGACTTTTTAGGAGATAACAACATCATCATACTACGTCCCTCCTTTTTGGGAGCTTGTTGAATCTCCGCTAAATCTTTTAAATCTGTTGCCATCCGTTGCAATAATTCTTCTGCAAGGTTACTGTGTTGTATTTCCCGGCCTCGGAACATAATAGTGGCTTTCACTTTATCACCAGACTCGAGAAAACGCTTTGCATGAGATAAGCGGACATTATAGTCATGCTCCTCAATTTTATAGCGCATCTTCACTTCCTTAACTTCGGCATTATGCTGCTTACGTTTGGCATCCTGAACTTTCTTTTTCTGTTCAAACAGATATTTACCGTAATCAATTATTCTACAAACTGGTGGATCAGCTTTATCACTGACCATAACCAGATCGAGACCTTTTTCCTGGGCCATCCGTAAAGCTTCTCTTGTTTCTACAATTCCTAATTGTTGGCCATCTGCATCAACAGCCCTAACTTTGGGAACTCTAATCTTTTCGTTAACTTGAGGGAGATTACGATTATTTTTTTTTTCGATTGGCATTAATTGGAATTTTAAAACGATGTTGGCAAGGATATTGGTTAAACTTTATGTGATATAACTTATCAATAATATATTATCATAATCAAATATTTTTATGCAAGCCTATTACATAACGCTGTTTTTCTCTAGCTTAACACAATGTACATTTTGCTGGTATGAGTGTAAATCTTAAGCAAGAGACTTTTTAGTTGCTTTTTTTTGAATAGATATGTTAATATTTATAATAATCTATAGTAATATAGTTATGCAATTCTGGGGGAAATAGAATATAAAGAATTGGGAAACAAAAGTAGGTAGTCAACGAGACTGGGTATGGCGAGGATGGCAAACTCGCTACACTTATGTTAGATGCCAAAGTAACTACAAAACTATGGAAGGCCAGAATCTACAAAACCCTCCTATACTGCTTTTACATGGTTTTGGTGCATCAATAGGCCATTGGCGACACAACATAAATGTATTAAGTCAAAAACATACAGTCTATGCACTAGATTTATTGGGCTTTGGTGCTTCGGAAAAGGCGATCGCCAACTACAATAGTAACTTTTGGGTAGAGCAAATATATGATTTTTGGCAGGCTTTTATTCAAGTACCAGTAATATTAGTAGGTAACTCTATTGGTTCATTAATATCCCTAGTTGTTACTGCTACACATAAAGATATGGTTGCAGGACTAGTAATGATTAGTTTACCAGACCCAACTGCTCAAGCAGAAGTAATTCCAAGTTGGTGTTTACCTACTGTTGAGTTGATTCAAAATATTGTTGCTTCCCCACTATTGTTAAGGGGTTTGTTTTTTATCCTTCGCAGAAGCTCAATAATTCGTCGCTGGGTTAAACTTGCCTATAGTAATCCCGATCTAGTTACAGAAGAACTAGTGGATATATTGGCAGGACCGCCGAGGGATCAGGGTGCTGCTCGTGCTTTTTGTATTTTATTTAAAATTATGGGTAGCACTAAGTTCGGTCCTAGTGTCAAAGCTATACTTCCTACTCTGGAACTTCCTATGTTGTTAATTTGGGGCAAGCAAGATTTATTCATTCCTGCCAAGTTTGCTAATCCTAGTCAGTTTAGTAAACTTAATTCCCGTTTAGAGTTTATAGAATTAGATAACGCTGGTCATTGTGCCCACGATGAATGTCCCGAAATAGTTAATCGTCTAATTCTTGATTGGATTGTTAAACAAAAATACTGATTGATCAACTTGACTAGACTAAATAGCTAACATATTTCTTGGGTTTTAGGCAAGGGTATTTTTACTTAGAGATGGAGGTTTATACAATAAACCAAAAATACCTAAGTGGATCATTGATGATATTGAAGGTCTGATTCATCTCCAAAGAGAGTGGGAATATCTACCCAGCTTTAAAAGCAATTTTAAAGTACAATGTCCAGTCTTTGAAAAACAATATACCAATGAACAAGAAAGGAATGAACTTCAAACTATTGAAAGCTATCATAATTGGAAAAACGCCAGTGCCAATACTCATAACTTACTCCTTGAGAGTTATTTTCAGGAAATGACATTTCAAAACCATATTGGTTGACATTTTTAATTAACCACTGAAAAGTTTTAGTTTCTCCAAACTCATAAGTAATATCTTTTTCTGGGAAGTTGCTATCAGCCATATCAATTTCCTATCCAGTGTGATGATCACTATAGCTGGGAGGAGCAGTAGTCTTTGCAACTGTTTCTGGAGAACCATAGTGCTGAATTTGGTATTGGAATAGTTGCTTTTGGTTAGCAACAGTGCGAAATCCTGAAACGGTTACAAGTTATATACTATCATCCACTGCTGCATATATCATTTACATCAAAGCAAAGGCTACTTCAGATGCCAATTTTTCAGGCTTTTGATACTCTGCACCAGTGGCATAACTGCCAATAATTACCATTTTTTGTGCTTTCCCCTCCGGGTAGGGAAAATGCCCAATTTTTTGTTCTTTTACTGTTAGATATGATTTTGACTTAACTGAGTGAGGGTTCACTGGAGTTTGTAACGGAGTAGAAAGAGGCGGAGCGGTTTTTTTTCAGGTGCTGGAGAAACAAGAACGGTAGGTGTAATAGAAGGAGAAGGCGCAATGGTTGCATATTTTTTAGTTAAAATTTCACAATTGCATAGCCGTTAAGAATTAGTCCTAACACTAATAAAGCAGTAGGAACAAGAAAACGAAAGCTAGTCCAGAAGCTATTGATCTAAAGTGTCCTATAGATTTATTTTTCACCTGTTTATTAATCTAGTCTTGTAATACCAATTTCCTAAAGTCCGACTACACATAATGCTTCAAGAATAAAATCATATCCTGTACAAGAAGCAATATCTTTTTGACTAAATCCAGTTAATATATTTCTCAGGATTCTGCGTCAGAAATCTAAGGAATCGAAAACTCGATTTTTCAAGAATTTTTTCACCTCTTTCCACAGTCTTTCAATGGGATTAACTTCGGGACAATAAGGAGGTTGAAATAATAAAATGATGTGATCAGGGATAGATAAATCATTCCCTAGATGCCCTCGCCCGTTATCTAGTTGAATAATATGAATCTCTTCAGGATATGTTTGAGAAAAAAGCTCTAAAAATCTTTCAAAGCAAGGAGTATCTAGATGACTAAATTCATAAAAAAAGGAATCTCCTGTTTTTGGTTCTACTAAACCATAAAGCCATAGATATTTAAATAGCCATTGATATAAACCAATGGGCTTAACACCGCAAGCAGTAATGACTTTACCTGTTATAGTTTTTAATCCAATTCTAGTCTCGTCTTGACACCAATAGCGAATTGGCAGTTGATTTTCCGAATATTTATTAATTAACTTAAT

Protein sequences of DBSCAN-SWA_2

>NC_008312|1384182:1469674|1401368_1402571_-|WP_011610675.1|DBSCAN-SWA
MSRATKVVLAYSGGVDTSVCIPYLKNEWGVKEVITLAADLGQGDELEGVRKKALDSGAVESLVIDVIEPLIKEYAFPAIQANALYENRYPLATALARPLIAKILVEAAEKYGADAIAHGCTGKGNDQVRFDVAIAALNPQIKILAPAREWGMSREETIAYGEEYGIPAPVKKSSPYSIDKNLLGMAIEAGELEDPWVEPPEEVYGMTKAIADTPNEPEYIEIGFERGIPVSLNGQEMGGIELITKLNQIAGNHGIGRIDMIENRLVGIKSREIYESPAMWVLIQGHRDLESLTLTADVTRYKRGIEETYSQLVYNGLWFSPLKGALDAFIQQTQERVTGVVRVKLFKGNAMVVGRKSDNSLYSFDLATYGAEDEFDHKAAEGFIYVWGLPTRVWSEKLRG
>NC_008312|1384182:1469674|1456762_1457209_+|WP_011610711.1|DBSCAN-SWA
MATVKRSDRLPMLRKAYLQVCSDLKENEKVLSWFEQLYQVTIPQTIWLQCELTLAEGFTNATRHAHKYLPRETPIDIEITMYTNYLQIRIWDYGQPFDLIEWLKAQPDPDIFASGGRGIRLMYAIADHISYTRTSDNRNCLLISKDYW
>NC_008312|1384182:1469674|1399968_1400772_+|WP_011610674.1|DBSCAN-SWA
MKEIIKNILTNLGQVKLPAPSYFDSLETYTVKKVSDADTFNVVANGSEVEMTVRFVYIDTPETPKGWGDSQVEKMNHKNKNPIYRSQFEWGEKGKDRLQELVQKSDNQVKVKVTGEENRPGRSPRCFGEVYLLDGTFVQHILVKEGLARVYYDYISECPREIAIMLFLAEADAEINQRGIWQELQSEFMAPWVFRSLKKKQKNFLKDIGKELKAGSINEAEFEAKFELKLQQQNQILSILQKELISGLITQAKFEDKCKEELNHLFA
>NC_008312|1384182:1469674|1388872_1389853_+|WP_011610670.1|DBSCAN-SWA
MTNKEPEKLENSTAKTRQLLGMKGAASGETNIWKIRLQLMKPITWIPLIWGVVCGAASSGNYSWNLENVLMSAACMLLAGPLMAGYTQTLNDFYDREIDAINEPYRPIPSGAISISQVVTQIVFLLLAGVGLSYLLDLSAGHEFPILTMLCLLGAFLAYIYSAPPLKLKQNGWLGNYALGSSYIALPWWTGHALFGELNLTIVILTLFYSFAGLGIAVVNDFKSVEGDEKLGLKSLPVMFGIGTAAWICVLMIDIFQAGVAVYLISIKENLYAVILLLMVIPQITFQDMYFLRNPLENDVKYQASAQPFLVLGMLITGLALGHAGV
>NC_008312|1384182:1469674|1412247_1412706_+|WP_044137173.1|DBSCAN-SWA
MLNTIATQIRKWFSAPEVSAHCDGPCGVYDPASARIYAEAVLSMTKKILDLDPKAGDHKTANTLSRYIAIKEEQAQKTKEDLLILWTDYFKPVHLEKYPDLHDTFWKAAKLCSACKVEVSLEHATELLAAVEKIHNMFWATKERDVTWYKAS
>NC_008312|1384182:1469674|1419956_1420268_-|WP_011610690.1|DBSCAN-SWA
MKTLPIDLQKAEINQICQQYNISKLSLFGSVLRHDFTTESDIDILVEFEPGKTPGLAIIRIEDELNYLLGRVVDLRTPKDLSRYFRLLRVLQEAMVIYEQVII
>NC_008312|1384182:1469674|1435220_1435445_+|WP_011610698.1|DBSCAN-SWA
MFGKFSPRKSASYTTLPGKAGVILLFREVTEKIELDPDDTPVAKIKVSLTRTLPKAKSKQPISFSQMWKEIDIE
>NC_008312|1384182:1469674|1433140_1434688_+|WP_155994643.1|DBSCAN-SWA
MIVILDFGSQYSELIARRIRETQVYSEVISYRTTAAKLADINPKGIILSGGPNSVYDEGAPHCDPEIWNLGIPILGVCYGMQLMVKQLGGEVERTQLAEYGKASVSIDDPTDLLTNIEEGTTMWMSHGDSVTKMPSGFEVLAHTDNTPCGAIADHNKKLYGTQFHPEVVHSIGGQVLIRNFVYHICKCEPTWTTEAFVEEAIREIRAKVGDKRVLLALSGGVDSSTLAFLLHQAIGDKLTCMFIDQGFMRKYEPENLVKIFHESFHISVKYVNARDRFLSILKGVSDPEEKRKLIGHEFIQVFEEESKRLGPFDYLAQGTLYPDVIESANTNVDPKTGERVAVKIKSHHNVGGLPKDLRFKLVEPLRKLFKDEVRNVGRSIGLPEEIVRRHPFPGPGLAIRILGEVTDKRLKILRDADFIVRDEIRQQGMYHDFWQAFAVLLPIQSVGVMGDQRTYAYPIVLRFVKSEDGMTADWSRVPYDLLETISNRIVNEVKGVNRVVYDITSKPPGTIEWE
>NC_008312|1384182:1469674|1412817_1413084_+|WP_155994642.1|protease|DBSCAN-SWA
MFPILKPGDEVLVDTKAYHHCAPEIGDMVVAEHPHRQELKIIKWVAFVDEKGDCFLVGENKEESTDSRSFGLVNRKRIIGKVKSKFPT
>NC_008312|1384182:1469674|1419415_1419658_-|WP_011610688.1|DBSCAN-SWA
MLYPKIKSAQVIDNYTLLVHFSNHKTRKYNIQKLLNKPTFFPPKNFAFCKNFQIDPSGSGIIWNDEIDISEHEIWINGTH
>NC_008312|1384182:1469674|1449237_1449534_+|WP_011610706.1|DBSCAN-SWA
MPNYKVTLKTPDGNSTIIEVPDDQYILEEAEEQGLDLPFSCRAGACSTCAGKVVSGKVDQSDQSFLDDDQMAAGYVLTCVAYPTSDCIIETHKEEALY
>NC_008312|1384182:1469674|1421105_1421984_+|WP_044137174.1|DBSCAN-SWA
MFKFRLLNQNSISENLEKYQRLTYPPYRPILDNLLDSKYIAISAEDNQEILGLTIGKIDYKKNIGEVLSLFVIPEYRRQGIGNQLLVALETEFRGKNCQQIDLIYIPNQTIIALEKIFQKNAWSKPKARMLIGLGERETIKNMAWLNLDQKLPLGYEIFPWGELTSKERTILEKSLWYPDILSPFTEEDIIEPINSLGLRYNHQVVGWMITHRISENTIRYTILFVKEELQSIGRGIALLARAIKLNLNHPEINQGSFALLINNEKMAKFTERRLKPYLASFRQSFISSKLT
>NC_008312|1384182:1469674|1386864_1387017_-|WP_155994296.1|DBSCAN-SWA
MYQDSLTDDGARNFETEDYKPWGICYYSRDKKWVIIKENGVKQRKQRKER
>NC_008312|1384182:1469674|1408254_1408719_+|WP_011610680.1|DBSCAN-SWA
MKGIILAVSIQKGNGIISGDDGKRYRFLLSSWYAEQNPKQGLRVDFDTTPEGEALDIYQDISDISASPSSQLNPKNRGIAAILAFFLGAFGAHKFYLGYSQAAIIMLIVSLVGSFLVIPTLVMSIIAFIEFITYLTKSDQEFYDTYLKNKKAWF
>NC_008312|1384182:1469674|1444637_1444775_+|WP_081432394.1|DBSCAN-SWA
MIIELIVTLSCLFGLPGRQTQRFIESVFQVDGIRFTCARLYHCIP
>NC_008312|1384182:1469674|1395949_1399156_-|WP_011610673.1|DBSCAN-SWA
MFTNFFIKRPVFASVCSLLIILIGLVGYISLPVQEFPSIDTPVVSVRTNYPGASPEVVETEVTEILEAEINGVEGVKTLTSSTREGSSSINVEFQLSRNIEAAAQDVRSRVSRAMRRLPNEVDAPVVSKRSSDEERIIWLSLTGEKYSSLELSNYADKFIKNILETVNGVGSVFIGGERRYAMRLWLNPQKMAARNITALDVKQALRQQNVEIPSGRIEGKSTEYPIRTIGRLQTPEAYENLVIRRNDDTSLTRFKDIGRAEIGAESNRTIARYNGKPAIGIGISKLSGANIIEVATSVKTRMKELSKDFPDGMEYYVSVDYSTFVEVAIKEVWKSLLFAICLVVLVIYMFLQNWRATIIPTITIPISLIGAFGVMFFMGFSINTLTLFALTLSTGLVVDDAIVILENIVRYIQQKGKTPMEAAILGVGEVVFAVIATTIVLIAVFLPVGFSGGGAGRIFNEFALTIAVSVVFSTFVALTLAPSLSGRILKKQEPEEQKNFISRLFTIPLNLFDYALSRISVIYDRSLRLLMRIKPLVILGFILSFWIIVWLFQQLPQGFLPTEDRGRVFVSVTAPEGVSIEYTDNVMGQVENKLAQVPEMKGYFSITGFGRSAQANRAFAFTNLKPWSERTKPGQAQQEVVKKLFRAFAPITDARIFPINPGSLPGTGLSRSIQFVLQGNDFEELVRVSEEFNNEAQQLPQLKNVDTDLKINKPEIVVEINRYQAANLGISVENIAQTLQIMMGGEDITNFTQGNQRYDVIVRAEDEFRNNLQDIEDLYVRTEQGVMIPLSNVVTVKTSTTPPEINHFNRFRSATITGSPAPGVSLGEALQALYDLADRVLPADMRIDLKGESSQFRDAGQATTYIFGLALIFIFLTLAAQFESYIDPLVILLSVPLSLLGAFGALWLADLEVNVYSRIGLIMLIGLATKNSILIVEFANQLLAEGMSITKAAIEASRLRFRPILMTGFSTIFGVMPLAFASGPGAASRVSIGMSVMGGMLVSTVLTLYVVPVFYVVMGKSLQFGLFRKHAQYSADGDEISNGSVNGNSKTAPVNDKNQDSAEKLSR
>NC_008312|1384182:1469674|1421953_1422169_-|WP_044136397.1|DBSCAN-SWA
MVEAIALKAEEKSASTRNREEFNQSQHIRFPRHSRRGGCIKFAIVLQQVPKELERKKKNYEFYVNLLLIKD
>NC_008312|1384182:1469674|1424442_1429596_-|WP_011610695.1|bacteriocin|DBSCAN-SWA
MRVKTKPFLQREATECGAASLGIILKYYGRQVPLMELRSKCGVSRDGTNAGQIVRTAREYGLTAKGGKSNVEFLEEIDLPVIIFWKFNHFLVVEGFDKKFAYLNDPALGRRKVSKEEFAQSYSGIVLQMEPGEEFVKGGKKRNFIAYLAVRLQNSKNALVFTFITGFFLSLIRLIIPAFSLVFVDQVLVEGLQGWLRPLLVGMAVTTILQFTIARMQYIFLRKLIIKLSITMNSKFMWHLLRLPMNFYAQRFTGDISSRAALNDTTVQLLSQVANTFIDTIMLVFYAVLMSFYNGVLAGITIVFGLINVAALYWLRQFRIEATLNLSEKKGKLSGYLLGSLGAIESLKAGGLESYMFSRILGIYSQVMNEEQKLNIQTQILTLLPTFLSTLSSAIILVLGGLTVMAGDMSIGMLVAFQTVASGFLNPLGKLINFASSLQELEASLERLDDVLDNPLDEDIEITEAVENDVENSVVEAGNNLEQLTFYDKKNAPNGLLIPYSPLKGKVELRDITFGYNPLKPPLIVNFNLLINPGSRVALVGKSGSGKSTIANLVCGLYQPLLGEVLFDDIPRQEIPRSVLTKSVAMVAQDISLFEGTIRENLTLWNPTISNSALTQACKDANIHEFIISLSGGYDANLLEGGVNLSGGQRQRLEIARALVNNPRILILDEATSSLDAETERVIDQNLRRRGCACIVVAHRLSTIRDCDEIIVLREGKVLERGTHQQLWHQGVYYRQLLEMEEGSQDFRQDILPELRYQELGINREIKGENIVEKSLVSTRLLANLDSKTKYYFLEGNQPLIFEFPQIIWFVKSGAVEIFYSLELDGELIGNRHYLFTVKQGELIFNSDAQTQGKLLGIALEKAELIQINLANTDLNEDFQSLSGSLVEKWLNYLWESQNSKAKIQNLELIDESVDSIPKDFSLPSFGKSELPNFSEIVSINNNFCNYLHQVILAEEQTEIFNSQRLKTYNQRSQAETMQNFVSVLYNRKTTNSLVSDFNDLLLAAVGAIGRASQIEIKPPLTQRKNFQNTIPEKQSPADYQIYLQEIARASRCRIREVKLRDKWWQKNSGALLGWLKLENLPVALLPKNNQYFLYNPKTQTSIPINQNVAATLSSTAFTFYRPFPIQVKKVWDIFLFAIKGYEWDAIKVMILGTIISLMGMVTPQASAILINNAIPDSDKLLLWQIALGLLAVTVGKSLFSLLQGIMSIKVSQGMQINLQSGIYDRLFRLNPTFFREFSLGDLLTRIAAISQISGLVNSAVITTIFTGLFSLLNLGLMFVYSKKLALIVLIVGVISFLITLISGIILIRFEREQEKLSGKIQGLTVELINGIQKLRVAAAEVRAFAVWGKKFQPQIQLNNRIFQINDIISVINEVVSLVTSIVIYWFAIQIIISAAQTGTPGLNIGTFIAFNSAMGVFLGGVTSLSDTITDVIGIVPLWERAKSILDSPIEYNPNLAHPGKLQGHISIDNLTFSYHQKSKLIVGKTEENLPQFNGVTVLHNISLEVKPGEFVAIVGPSGSGKSTLFRLLLGFEQPQTGSIFYDGKNLAELDLEAVRQQLGVVLQNGQVITGSIYQNISSGELVSPQVAWEAAQKVGFADDIEKMPMGMHTIVSEGGGNISVGQRQRLLIARALILQPKIILLDEATSALDNKTQAIVTESLERLNVTRVVIAHRLSTIRNADVIYVMSQGRVVQKGRFDELMAQEGLFRRLVNRQLA
>NC_008312|1384182:1469674|1441708_1442476_+|WP_011610701.1|DBSCAN-SWA
MIKFIRRKIFKPFLNILLKANCPLCQRSADREFCQYCEKQVWHCQFPGGGEIFSGEVPIFVWGQYKDSLKRAIAAMKYEDHPEIAKPLGYWLADGWLATAPREKAVVIPIPMHKKKQRERGFNQSELLANSFCEATGLQIWRNALVKLKQTQPLYNLSSQERLEMVKDIFAIGKDFRNRSSYAPVLLVDDIYTTGATVNSAIEVLRKAGIKVVGVLAIATTKEPTAKKPLLKSKKVVKKIYFSKVEMKLKNIVSQ
>NC_008312|1384182:1469674|1407783_1407951_+|WP_011610679.1|DBSCAN-SWA
MSILRILAAIFLPPLGVFLTVGLGGAFWINLLLTIFGFYIAGIVHAIWVIAKHDN
>NC_008312|1384182:1469674|1403155_1404088_+|WP_011610676.1|DBSCAN-SWA
MFFSIIIPTYNRLGILEKCLRALESQTYEQHITEYEVIVVDDGSTDDTIPWLKANATEFPHLQLWPQSHQGPAAARNLGVEVARGNFIIFIDSDLVVTDNFLQAHANTLIKYGKKSNCIFTYGRVINTCNFDFPTLEPLKLTDFSAAFFATGNVAIARHWLIEAGLFDTNFNQYGWEDLELGIRLKKLGLKLIKCSEAVGYHWHPPFSLEQLPRMIDREIQRGKMGVLFYQKHPILEVKIMIQMTYFHKLLWGVLSLGGRLNEKTMAVFLQWLIDRGKSQLALEISRIFLNWYNVKAVYSAYANIDGFRK
>NC_008312|1384182:1469674|1445435_1445594_-|WP_155994305.1|DBSCAN-SWA
MKLIRISENIVTLKLSIKLTSRSQLICGYRSTTKELSWMKVAIVNYSPIRSN
>NC_008312|1384182:1469674|1387058_1387208_-|WP_155994298.1|DBSCAN-SWA
MAITYQSNIQNMVDTWNMEVPTGLLGLGWNMSYEIIAIDNRNTGANYND
>NC_008312|1384182:1469674|1448618_1448921_+|WP_011610705.1|DBSCAN-SWA
MATYKVTLINEEEGINQTFDCPDDEYILDAAEEQGLDLPYSCRAGACSSCTGKIESGTIDQADQSFLDDDQMTAGYILTCVAYPTSDCTIRTHQEEGIAS
>NC_008312|1384182:1469674|1446530_1447538_-|WP_011610703.1|DBSCAN-SWA
MTQINISSSFCSIPIRVGIVGTGYAAKARAETLKADERSLLVTVAGHTPEKTEAFSQTFQVESAASWQQLVERKDLDLVIISTINRDHGAIALAALENNKHIIVEYPLSLDPTEAESLITLAKKKNKLLHVEHIELLGGLHNTIKESLSKIGKIFYARYVTINSKQPASQKWTYRYSLFGFPFVGALSRFHRFTDLFGQVDTVNCQSQFWYTEVDLYKACLCTAQLRFNNNVIGEVVYGKGETFWHSENTFTLYGEKGKLIFTPQQGQLLQGEKIQTIEVGARRGLFAKDTKMVIEYLLQGTPLYITPEASLYTLKVANLSQKSSHNSGKATKFK
>NC_008312|1384182:1469674|1416501_1418502_+|WP_011610686.1|bacteriocin|DBSCAN-SWA
MTNELPKTDSLKKKGRIFSQDSWEKISSPEEFDELIQVVTVKNWLSFSIFGGLVLVGILWSIFGKIPITVTGKGVLIRPRQVVTFQSAIEGNLDSLKIRDGECVKKDEVLATINPSQLKKQLELQRQKLFLFQTQALDTQRLEGQRTQLEVDGLTTKAEGLRQRLRDTQSLTPTLQSNTLEALREKGQTLEQRLQDMQAVTPRLKEEKLQEINKQRVSLEKRLGDAKKLTPELRDKKLQAIAEQKITLQERLQSAKSLTPILRDKNELALQQQRESLKQRLKDAQELVPVFEQRLTKRQKLLDDGAISQDNLLQTEQEFRQNLQSIAQIKTELKQVEVQEAETAEKYLQNFSTINEIEDKLKDLEVEEVETNQRYLDNVNTIREIEGQLQGLDSQTTETSKQFLDNLNQINEIKVQLQEVKLQETEAMEKFLESQNIMAQLKVDLLDLETQKKRLEQENLEAANTRKNQIEEVNREIAQLEKQVADNSKILSPVDGCILEIKGTVGQYVSPGTVLGKINVQGRLSGLMAVSYFPVKDGKMIKSDMKITITPDTVKRERFGGIIGNITSISSFPVTKEGASFVVGNPEIVENIIGESGGQIETYAQLRKDDNTFSDYQWSSSKGPQKKFTAGTTITARVRVEERAPITFVLPILREWSGVYLFKSKS
>NC_008312|1384182:1469674|1435655_1437428_+|WP_011610699.1|DBSCAN-SWA
MPQIRFPQTKNQIVILSCVAVFLWLFSCTPNSPKSLPLAELKRSKESIVVSAHPLASEAGKLMLEKGGNAVDAAVATAFAISVVEPFSAGIGGGGFLLLGTPPENSETQQYKIRALDFRERAPKAATRNMYLNEKGEVEKRASLDGHLAVGVPGTVAGLYNIHKSLGKLPWKELLKPAIRYARDGFELRDDFVSKLEKRLEVINKNPAARDIFTKNGQAYEPGDLLIQTDQAQTLETIAENPQSFYTGKIAQAIATDMAKAGGLITLEDLQNYTPIWREPICGKFRQAKVCAMPPPSSGGVHLLQILNIVGETNLQQWGRENADTIHLLTEAMRVAYADRSLHLGDPDFLEVPVKELTSLSYAQQRRQEISLTKVRRSTEVQPVSPEVLRSNILESPDTTHLTVVDQERNVISMTYTINGSFGAGVVAAGTGILLNNEMDDFAAAPEAPNLYGLVGDEANAIAPRKTPLSSMTPTIVTDNGRLIMATGSPGGSTIITTVLQVILNVLEYKMNVAEAVSAPRFHHQWLPDKLILETGGFGEATVNELKQRGHNVVMQRGWGNANVVFQDESGMLEAAADPRGEGEAMGTGQ
>NC_008312|1384182:1469674|1404360_1404582_+|WP_011610677.1|DBSCAN-SWA
MIEPDFPHIILTFEYKGWKVEIDQGEMNGSATYAVWANYNNGCVVAVPLASSRQEAVRRAKQWINTRNKKNKT
>NC_008312|1384182:1469674|1438026_1438170_-|WP_155994304.1|DBSCAN-SWA
MLGHTSRVLFYQDKGKDEKAIAEFNQGIQRVPKNANSDYFWQFLGLL
>NC_008312|1384182:1469674|1414772_1416365_+|WP_011610685.1|DBSCAN-SWA
MTIAIDFGTSNTVISRWNQTTKQPEIVKLPNISILSVENPPLIPSLVYVENVAEKKVVVGQQVRDKGYDVNTESRFFRNFKRGIGANVQGFLPELDGQIVSFEQVGKLFLEEVVAGLQKVPLPVESLIFTVPVDSFEAYRNWLGEVCQSLEVEQVRMIDEPTAAALGYGMADAEILLVVDFGGGTLDLSLVRLDNVMAKQPLGYILKWGKKSYGNNSSQKARTARVLAKAGENLGGSDIDNWLVDYFVKSQGIEKSSLVTRLAEKLKIQLSLQQEGTEVFFDDESLESYELGLGRDAFEEILRENGFFASLDQSMSRVLQQAKRQGIELSDIGAVLLVGGTVQIPAVQRWVREYFDAGKIRCEKPFEAISQGALQLVQGVEVKDFLYHGYGIRYWDRKKNAHGWHPLIKSGQPYPMSSPVELVLGASMNSQPSIELVLGELGAESAGTEVFFDGDRLITRKVSGEQTAVQLLNDREGGRSIAQLSPLGNPGRDRIKVLFWVDESRFLRITVEDLLTNEILLNEQAVVQLS
>NC_008312|1384182:1469674|1409260_1410328_+|WP_011610681.1|DBSCAN-SWA
MQIVNSQISIEKTSHSRIKEQDINNTPFGKVFSDHMLVATYANNSWQEVKITPYGNISIRPSLSVLHYGQAVFEGLKAYKNYQGKPVLFRLEANYKRINNSAFRLCMPSIPKEIFIDGLKELIRLDTDWIPTKSDSALYIRPIYFATDESVGLKPANSYKFIILSSPTGTFYSAPVKLIVTDKYVRASEGGTGAAKCAGNYAGSFLADKEAKEQGYDNVLWLDGKEKKYIEECGTMNVAFVINDVLITPKLTGSILGGITRDSALTLFRDMGVKVEERLISIDEVAKAYEAGNISEAFGMGTAATIAHISVINYQGKDMILPPVDERKYASQVLQKLEDIKTGKVTDPYGWICQL
>NC_008312|1384182:1469674|1466316_1466853_-|WP_011610716.1|DBSCAN-SWA
MPIEKKNNRNLPQVNEKIRVPKVRAVDADGQQLGIVETREALRMAQEKGLDLVMVSDKADPPVCRIIDYGKYLFEQKKKVQDAKRKQHNAEVKEVKMRYKIEEHDYNVRLSHAKRFLESGDKVKATIMFRGREIQHSNLAEELLQRMATDLKDLAEIQQAPKKEGRSMMMLLSPKKSS
>NC_008312|1384182:1469674|1384182_1384845_-|WP_011610667.1|tRNA|DBSCAN-SWA
MVRVRIRQHVNPLASKYQQSVTIPNFSDIYADIKKPLYLDIGCARGRFLWQMAQVEPEWNFLGLEIREPLVIEANNWRDEKGLNNLHYLFCNANISLGKIFESFPKGILKKVSILFPDPWFKRRHQTRRVVQPKLVEDLANYLTVGGEVFLHSDIEKVAKEMCNRFSAHGSFYRSYNDWLKENILPVLSEREKVTLGKNQPVYRALFIKLEEPTPNIISP
>NC_008312|1384182:1469674|1410905_1411763_+|WP_011610682.1|DBSCAN-SWA
MIKQGSFKSILSIFKAPAGLIAGSTYHFRALIIFVKNPRLINYIIAPIFINIVVGIFLYISLLLPGISLINTIFNNLSLQFDSLIYQLPTWLKFLSYLDNALGLLFKLILFTIFLLIIGFLLVQFGVILGSPFYGQLSEQLEKTRTGTLPEASSGLLSIIRDIYRAILFELKKVALLLAIGLPMLLLNFFPGGSLIATIGGIALTTSIVCLDFFDGPLERRKLKFREKLKVVYRSLPASATFGLICQVLITIPIVNFLAIPICVVAGTLFCCDRVLPKLLPNNQT
>NC_008312|1384182:1469674|1447843_1448134_+|WP_011610704.1|DBSCAN-SWA
MATYKVTLKTPDGDQVIDCPEDEIILDIAEDQGFDLPYSCRAGACSSCAGKVESGTVDQDDQSFLDDDQVKEGWVLTCVAKPTSDCTINTHQEDNL
>NC_008312|1384182:1469674|1443312_1444083_+|WP_011610702.1|DBSCAN-SWA
MEWQENSGNWVLIPSRPKAIIHFLGGAFVATAPHVTYRCLLEILANQGYAVIATPFINTLDHLAIANNVLSSFENCLNHLYTSEILRKKSLPIYGIGHSMGCKLHLLMGSLNSIARAGNILISFNNFGARNAIPMVEQISSVVKVEFTPSPKITNSIIQKRYQIRRNLLIKFNNDNIDQTLRLSDILRLRFPSMVTVQRLNGNHLTPLGQDLSWSVGQVYTPVDAIGQWLKQEIYKDFNKLQREILLWLNPLAPIS
>NC_008312|1384182:1469674|1467121_1468048_+|WP_044136410.1|DBSCAN-SWA
MKNWETKVGSQRDWVWRGWQTRYTYVRCQSNYKTMEGQNLQNPPILLLHGFGASIGHWRHNINVLSQKHTVYALDLLGFGASEKAIANYNSNFWVEQIYDFWQAFIQVPVILVGNSIGSLISLVVTATHKDMVAGLVMISLPDPTAQAEVIPSWCLPTVELIQNIVASPLLLRGLFFILRRSSIIRRWVKLAYSNPDLVTEELVDILAGPPRDQGAARAFCILFKIMGSTKFGPSVKAILPTLELPMLLIWGKQDLFIPAKFANPSQFSKLNSRLEFIELDNAGHCAHDECPEIVNRLILDWIVKQKY
>NC_008312|1384182:1469674|1454097_1454445_+|WP_011610709.1|DBSCAN-SWA
MNNLVIKYIEPSGIIDSTKTTSFRQDISEQVNAGADVVVIDFKEVTFMDSSGLGALVIALKTVRAAGRKLVICSINEQIKMLFELTSIDRVFRIFPNREEFKKATNISLQPQSKS
>NC_008312|1384182:1469674|1419000_1419309_-|WP_011610687.1|DBSCAN-SWA
MTKYNEIEKGLNKVKDELKKVDFKKIDNELHKVQNELKKVDFKAINNEWNKAKGNFNKADLKTINNEWNKVKNNFNKADFKTMTKKISSELQKVSKKINKKP
>NC_008312|1384182:1469674|1406489_1407422_+|WP_011610678.1|DBSCAN-SWA
MANNMVASDLWISEHITPWDIYVHGLTKVLAYKKTAYQEMYIVETGIYGKALVLDGKWQSCTGDEFLYHEPLVHPAMICHGSPRKVLVLGGGEGATIREVFRWQSVEKVAMVDIDGEVVEACRQYLPEMHANAFDDPRLQLVIGDALKFLETFGESWDVVISDLSDPIEEGPSFQLFTKEYFEKILRVLTPGGFFVVQAGPVSPGEMKLHARIVNTMKAVFPFVQSYNSNIPTYGRPWGFALGSRKMVNSRPEPEMIDKLLKEKTIGGFRMLDGTTLLGMLQVPLHLREAIATETKIYTLAEPPKFGRPA
>NC_008312|1384182:1469674|1455459_1456593_-|WP_044137179.1|DBSCAN-SWA
MYKILVIDDDTTVQELLRRVLGKQGYTVTVASNGEEGFKQAQLLQPALIICDWIMPRLTGIEVCRKVKASSDLSTTFFILLTSLGSVQDLVKGLDAGADDFISKPININEMKARVRAGLRLHQLSQDLQTQKQLLEAELAEAANYVSSLLPASVTEPVKVESQFIPCRKLGGDCFDYYWLDENYLAVYLLDVAGHGLRAALPSVSVLNLLRSKAIPNLDYYKPSDVLRALNNTYQITSQNDKYFTIWYGVYNLSESQLVYASAGHPPAILISGDSHLAQVSKLRTPGMPIGMFPEATYIDDSCIVEKSSSLYIFSDGVYEIYLSDGEIWGIDNFINLILEYYRYGYCDINKILDYIQKLNCSDVFSDDFSLLKLIFS
>NC_008312|1384182:1469674|1420681_1420915_-|WP_011610692.1|DBSCAN-SWA
MSPLLTKILQEIEQLTIEEKFQIITYTTEQLKRQTTIPKTSKHSLCNLRGILPNILEGKDAQEWVKELRQEWQQREQ
>NC_008312|1384182:1469674|1453071_1453713_+|WP_044136401.1|DBSCAN-SWA
MNQSFRINYAPILQNLMQDANISSYRELSQKARVSELQVIRLQGGLASQMRVDILLKISLALGITLTELLTNFAPELVKNLPKNSTSALEQECKNLQKELEQQKQFLMQEFQQSSLQILESWLQQWPTVIYKAKQNPSLAAIKILPLLRPVEKLMGQWNVESLAPVGAEVPFDPQLHQLMEGYAQKGEMVTIRYTGYRQGDKLLFRAKVSPIS
>NC_008312|1384182:1469674|1450073_1451690_-|WP_155994306.1|DBSCAN-SWA
MKLLAKKSQKIIKNTIFITALLLGLNITPVKAVEEYNRLLKIGIIQRFGAKPKDKIIIKATPGDKLTLRFKTPAGEETLTTEKVELKIKVKPLKKPLLKERLILSSHRSYENAEEDAQLWKKKGIEVEVAQPGRWKVWGKREVYKTPLLRRWLLESLQANNNTNIYLELEALKQRPTAYWSMNGYIYHRHELYITAGKNEVIINNQFNQDRATLEERRYVGSLKLQPNAYGTYTLVNNVPIETYIRGVVPHELGAWPPKASLEAQSILARTYALKNLHRFMVDNYELCANTHCQVYKGLDVYPETDAAVTATRGKVLTYKDELIDAVYFAVSGGVTAAFNDLWNGTKRPYLIPVVDATNNIWDISKNSLATDQNFRKFMSIKKGFNEDGWREFRWREVVSLPDISGYLRGYFQRKKSPFAQFNTIKKVAVTKRSLAGRVLKMTVETDRGIIELNKDEVQNAFWVPWSTLFYLDSIYKPDKTLWGYAFVGGGFGHGVGLSQKGSIKLAELGWSSDRILSFYFPGTEVQTLSKLANFGKK
>NC_008312|1384182:1469674|1387488_1388583_+|WP_011610669.1|DBSCAN-SWA
MTITYTFLGKGGTGKTTIAFATAKRYASQGKRVLFVGQEPASTLSLILGANIGPEPTEIDSNLKAVHIQAASLLESGWKELKKLEAEYIRTPFFKKVYGQELGVLPGVEGILTINAMQEYSASGKYDLIIYDGTGDKETLRLLGSAEIMSWYIRRFRQVILDSDLYKAISPFVQPVSNAILNVDWTGNNFSQPTEKINELLDNAKATIADPNRVAAYLVTTKDKAAIATARYLWGSAQQVNLTVGGVILNQADNVDNITAEFSPLSVTPVPHGSNENWQLLMDALPDFSQAVKAPKPIIIDIQKSQVSLFLPSFDKKQIGLIQDGPEVTIEAGDQRRNIFLPPPLSGRPVRGAKFKDDYLIISF
>NC_008312|1384182:1469674|1437789_1437993_-|WP_044136399.1|DBSCAN-SWA
MKRRLLNINKLLTLTRIADACYGRGSVYYLHGVGDQQQTIKDFEKAADLYKQQADQEGSQNFLDKLK
>NC_008312|1384182:1469674|1422257_1423010_+|WP_011610694.1|transposase|DBSCAN-SWA
MPRKPRNFQIGHSYHITTRCNNREFKLSRRECREVFLYAIKKVSTKYNFRLYALCIMSNHVHYLIEPLQPEDLPKIMHYLNWYTAMCFNRMLKRTGHFWEKRYYCNGFPSSDRERALNTLRYIHGNPKAAKMRCGFFYDFSNYGSYECLTNDGLTQWHPAFLELANTLDQCAQKYKEFCKKYKSKQKDSRKCHWGSKLLGGIVLSFDGRNSRSAKKKKLSTPFDFPPTVMPDNEELAKVVSQFVVANRPN
>NC_008312|1384182:1469674|1439018_1441514_-|WP_011610700.1|DBSCAN-SWA
MYKFYWLDQIKSSDWNIVGEKAFYLADLMDKGYPISPGFVIPANTLWQFLERINWSDPLLANFPDSSLNFNIDDYQQWQHISQSINYYIFSADLPLELVSSLESAINNLNAESLIFQPYLASPKLETFGILDVKICQAKSEKFTQVIKQAWSEIFKAKSLLYWHIHQVDIQKLQPVILVQSLQSAIASGTMQAFANSWEIQATYGLGISIELGQVIPDSFLISPKNYTIQEKKLGNKIIAYNLDTAMTKVSYINTWQEIDNTQMPIPDNLLGLQAFLLPENVQKEFALRDKYLQLLLEITKKITNEFPTSFYFKWTLFKSDNHEENQLLITDFKDMQTKSKKSENSTALTREKQKKSLEKLDSPIVTGIGVSEGKVTAQAVVIKDFNPQLKEVYKEKILVVSAVIPSYLPLLKNAAGIISEQGGITSHAAILSREIGIPAIVGATNSTKIIKTGNYLLVNGNNGEVHLVKKHKNYPKKLDIEVEKKSFHSKTLFPIGSKLFVNISQINSIKKAQNLPIDGVGLLRSELMAIELLENRHPLWWIKQGRESELIDLMVENLTQFAAAFAPKSVFYRSFDLVLFNYSYQEKNMTKKLEHSSLNYPNNQDNQYSQNIHDQNIFQELSFSYKSNYYNPILGQHGTLSYMLEPRLLDLEINILSAVYKLGYSNIHLILPYVRSLEEFQFCRSRIETKWKDKPNHFQIWIMAEVPSVLFLLPEYVKEGVQGIAIGTNDLTQLLLGVDREKEEIKSYFNTRNPAVMMAIKDLIFKAKSAGIPCSICGDAPALYPEIIDDLIRWGITSISVNLNAVEKTYKAIARAEQRLILEAARLNIK
>NC_008312|1384182:1469674|1457998_1458160_+|WP_081432395.1|DBSCAN-SWA
MGLDLPVPDDSTVSSKLNKLNIVYSVIPITKGIHLVVDFTGVKFTVKENGKLA
>NC_008312|1384182:1469674|1413525_1413684_-|WP_155994300.1|DBSCAN-SWA
MIFYSTRKNHKSRRFEPEIARQQIAIALILQSSKKALLFPPAILKKNLIYYS
>NC_008312|1384182:1469674|1461791_1464824_-|WP_011610715.1|DBSCAN-SWA
MEVRNLKSYTGLGDKLLISLNLRSEEVERTLLMFVVYTLTSIGLIWLELSTVSLFLDQYGAEKLPWIYIASAGIGSGLGFVYSWLQKIMPLRRVIVVILLLMAIPLFLFRLGIGIENIKIAGLSLAFLTTFMMWLWVEACYLLNDLNSSITGNQLFNIREIKRTYPIISSGFLVAGVISGFSLPLIISFVSLNNVTIVSGLMVLFGSGILLYLSERYQQSFPDSSRWIPEDEEQEFSTRIVKGPLQGYILPLIIFFVIAEVLYVLVDFQFFYQLELENRSLNGANQIASFLGLFEGILSTCQVVTQWFASSRLVERIGVFGTAMVLPLGAIALGLFSLTGAITGLLSVFIGLVILRFLDELLHYTLIETTGPVLFQPLPENIRSDVQTMVNGVAEPFSTGLSGLIILAILGVSRLILDSNQRLFSDQQGLVFVIAIIISALVWLGVILLIRTQYVNLLVRSAGKGRFAVLDVDMRALKRSVVETLERGTAEEDKRSCIELLSQIDKKNIGEILAPLLGVMSPALQSQSLEVMLNHPNPAYLQQVRSLTQTSLPAQVLALALRYIWLTESKSDVSQLRPYLQPSVDPVVRGTAAALIMRRGDREQKAEATNVLRRMITSKLEKERVMGVRALGEADYLQGLRLYIPSLLQDESLRVRKYCMDVIAATHLEGYYPSLLRGLSYKSTRESALQALVRLGNDAIPMLVKLADDAHKSDLVRLQAWTAISEIGTIEALDSLVNRMMTTWGTTRRNILRRLLKMPEEIGIEGVLERVGRSGVEILVEQELMFLGQIYAGIVDLSGVSINSENSLSSALEKSNGKLTTDYTEILLRSLQLLELDAIEQCFLLMKFLYPLGSIKAAALNINSDSRSNVARGLEILDNTVDISCKRSLIDILDQKSYEEKLNSLSEMVIYQPMAPSDRLRHLLDFRHFLSEWALACCLQMARAARWSLTAEQTLVCLRHPTGFVREAALAYLRMASQRALVELLPHLRNDPDPLVAAQVEQMIVEFGIS
>NC_008312|1384182:1469674|1469218_1469674_-|WP_081432519.1|transposase|DBSCAN-SWA
MKLINKYSENQLPIRYWCQDETRIGLKTITGKVITACGVKPIGLYQWLFKYLWLYGLVEPKTGDSFFYEFSHLDTPCFERFLELFSQTYPEEIHIIQLDNGRGHLGNDLSIPDHIILLFQPPYCPEVNPIERLWKEVKKFLKNRVFDSLDF
>NC_008312|1384182:1469674|1391234_1393301_+|WP_081432523.1|DBSCAN-SWA
MLSQKFQEPLQAPKFDGRKSQKKKVNPVEKKTGKKVIDVNIKGILLSWKLWLGLGLIGISSIMIYGGWMWRKLEQSLPEVADISSYRRDGTLTIKATDGKIIQQTGPATREKIKLQDIPTPLVQAFIAVEDRRFYEHRGVDYPGVIRAFILNIIARDIVQGGSTITQQLARMVFLDMEQSIWRKLREAMLAWKIENELSKEEILELYLNIVYLGSGTYGVADAAWVYFSQPVFGLTLAQMATLAGLPPAPSQYSPLVNEEAAKRRRNLVLKEMQAAGLISDERTKRAIAQPMKIKPSAPKRLIVEAPYFANYIQKELPKYVSSEVIMAGGLTVETTLDRRWQEIGEKVIQEAVDIDGYRQRFDQAALVAIDANTGEVKALVGGRDFAKSEFNRAIQAQRQPGSTFKSFVYAAAVAAGIPPTNGYRDLPFTVDGYKPKNYGKKYGGWRSMIDSLAYSVNVVAVQVLIDVGFEPVINLAKDMGIKSEVKATYSMALGSWEVNLLELTNAYATFAAQGKYIPAHGIKKVINQNGKVIYESNFKPKQVLDKDSAAIVTWMLENVVKYGSGANAYLSDRPVAGKTGTTEEARDLWFIGYIPQVATGIWFGNDDNKPTWGVSSTAAYNWQQFMRKVAKDIPVKNFPKKPSFYDRKPTIESKPVTPRWTRYGNVGPDGRELEKRNYYRDYYDGSY
>NC_008312|1384182:1469674|1420321_1420636_-|WP_155994302.1|DBSCAN-SWA
MGFFRFCSDYLAILIIHITSQKNLSVQQQFINILTSQDKINFVDINSETALIAADIRVRYNLKLPDALQIATAIQSNCDAFLTNDLQFKKVRELSILVVSELTL
>NC_008312|1384182:1469674|1394262_1395375_+|WP_011610672.1|DBSCAN-SWA
MFDCIIVGSGPAGASAAYHLAKNGRSVLVLEKETLPRYKPCGGGVSPIVQEWFDFDFTPAISLKINSICYTWKKGDLVEVKLQNKQPIWMVRREIFDYFIIQKAQKQGAEIRDKTRVIGIEFKNNNWQVYTDNQSFTSPYLIAADGAKGSMAKWLGFKNRKRFAGGAMEIEIPVKNQKIDSAYFEFGMLNNGYVWNFPKADGYSIGVGTFWRKHGQNFTALLTEYTSMFEVNIQNVQKFGHPLCLWNGNQKLHTQNAVLAGEAACIVDPFTAEGIRPSIFTGVKAARAIHNSLNGDLFALEKYTQIINEEWGKDMVWAQRLAQGFSRFSHIGYQVGVKRPHATNIMTKIMSGELRYSDVVGSALRRLWQR
>NC_008312|1384182:1469674|1385318_1385525_-|WP_155994641.1|transposase|DBSCAN-SWA
MSNAIPKFSKEVGYANLKAAQLKIARLLRKVVSIRQNGLHKLRIYLTENHGKIVIENLNFRVMFPWVT
>NC_008312|1384182:1469674|1430591_1431749_+|WP_011610696.1|DBSCAN-SWA
MTEPIAEPIAGYTLPVFACAAAVAALGWLRQNVSSSSTVSINLLEPREIVDIPIQQVALLKNNTALAVTRSDPGNNLDLTHNTPIWAMVELVKVCQTDTSEKIVIIGGEGIGYDINSREAAIYNYAQRLLQENLQPLLKQNEQVIVTIILPEGRQLAARTSNSAFGIVEGLSLLGTTGVSQPLSVPGQLEVYQEELQQKAAQFQSLVFCVGENGLDIARKMGISPQQTVKTANWLGPMLVAAAIAGVEYILLLGYHGKLIKLAGGIFHTHHHLADGRLEILTAHCANIGVPTSVVQKIFACPTAESALKLLRSIDTNQKNDLVGKVYGAIASKIDQRCQAYIFNHSQKQVQVGSMLFDRDRQIFLKTKVADQVFSQIFSFEDHKK

Homologous phage analysis in the prophage region

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_011610667.1|1384182_1384845_-|tRNA	tRNA (guanosine(46)-N7)-methyltransferase TrmB	NA	NA	NA	NA
WP_155994641.1|1385318_1385525_-|transposase	transposase	NA	NA	NA	NA
WP_155994296.1|1386864_1387017_-	hypothetical protein	NA	NA	NA	NA
WP_155994298.1|1387058_1387208_-	hypothetical protein	NA	NA	NA	NA
WP_011610669.1|1387488_1388583_+	ArsA family ATPase	NA	NA	NA	NA
WP_011610670.1|1388872_1389853_+	chlorophyll synthase ChlG	NA	NA	NA	NA
WP_081432523.1|1391234_1393301_+	PBP1A family penicillin-binding protein	NA	NA	NA	NA
WP_011610672.1|1394262_1395375_+	geranylgeranyl reductase family protein	NA	NA	NA	NA
WP_011610673.1|1395949_1399156_-	efflux RND transporter permease subunit	NA	NA	NA	NA
WP_011610674.1|1399968_1400772_+	thermonuclease family protein	NA	NA	NA	NA
WP_011610675.1|1401368_1402571_-	argininosuccinate synthase	NA	NA	NA	NA
WP_011610676.1|1403155_1404088_+	glycosyltransferase	NA	NA	NA	NA
WP_011610677.1|1404360_1404582_+	hypothetical protein	NA	NA	NA	NA
WP_011610678.1|1406489_1407422_+	methyltransferase domain-containing protein	A0A1C9C533	Heterosigma_akashiwo_virus	1.6e-13	27.8
WP_011610679.1|1407783_1407951_+	YqaE/Pmp3 family membrane protein	NA	NA	NA	NA
WP_011610680.1|1408254_1408719_+	TM2 domain-containing protein	NA	NA	NA	NA
WP_011610681.1|1409260_1410328_+	branched-chain amino acid aminotransferase	NA	NA	NA	NA
WP_011610682.1|1410905_1411763_+	hypothetical protein	NA	NA	NA	NA
WP_044137173.1|1412247_1412706_+	superoxide dismutase, Ni	NA	NA	NA	NA
WP_155994642.1|1412817_1413084_+|protease	nickel-type superoxide dismutase maturation protease	NA	NA	NA	NA
WP_155994300.1|1413525_1413684_-	hypothetical protein	NA	NA	NA	NA
WP_011610685.1|1414772_1416365_+	Hsp70 family protein	A0A2H4UU19	Bodo_saltans_virus	2.0e-16	25.2
WP_011610686.1|1416501_1418502_+|bacteriocin	NHLP bacteriocin system secretion protein	NA	NA	NA	NA
WP_011610687.1|1419000_1419309_-	hypothetical protein	NA	NA	NA	NA
WP_011610688.1|1419415_1419658_-	DUF2442 domain-containing protein	NA	NA	NA	NA
WP_011610690.1|1419956_1420268_-	nucleotidyltransferase	NA	NA	NA	NA
WP_155994302.1|1420321_1420636_-	PIN domain-containing protein	NA	NA	NA	NA
WP_011610692.1|1420681_1420915_-	hypothetical protein	NA	NA	NA	NA
WP_044137174.1|1421105_1421984_+	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_044136397.1|1421953_1422169_-	hypothetical protein	NA	NA	NA	NA
WP_011610694.1|1422257_1423010_+|transposase	transposase	NA	NA	NA	NA
WP_011610695.1|1424442_1429596_-|bacteriocin	NHLP family bacteriocin export ABC transporter peptidase/permease/ATPase subunit	W8CYL7	Bacillus_phage	2.0e-25	24.8
WP_011610696.1|1430591_1431749_+	cobalt-precorrin-5B (C(1))-methyltransferase	NA	NA	NA	NA
WP_155994643.1|1433140_1434688_+	glutamine-hydrolyzing GMP synthase	A0A1V0SH76	Hokovirus	1.1e-22	36.2
WP_011610698.1|1435220_1435445_+	hypothetical protein	NA	NA	NA	NA
WP_011610699.1|1435655_1437428_+	gamma-glutamyltransferase	NA	NA	NA	NA
WP_044136399.1|1437789_1437993_-	hypothetical protein	NA	NA	NA	NA
WP_155994304.1|1438026_1438170_-	hypothetical protein	NA	NA	NA	NA
WP_011610700.1|1439018_1441514_-	phosphoenolpyruvate synthase	A0A1V0SGR7	Hokovirus	1.9e-26	25.8
WP_011610701.1|1441708_1442476_+	ComF family protein	NA	NA	NA	NA
WP_011610702.1|1443312_1444083_+	DUF1350 domain-containing protein	NA	NA	NA	NA
WP_081432394.1|1444637_1444775_+	hypothetical protein	NA	NA	NA	NA
WP_155994305.1|1445435_1445594_-	hypothetical protein	NA	NA	NA	NA
WP_011610703.1|1446530_1447538_-	Gfo/Idh/MocA family oxidoreductase	NA	NA	NA	NA
WP_011610704.1|1447843_1448134_+	2Fe-2S iron-sulfur cluster binding domain-containing protein	A0A222YX16	Synechococcus_phage	1.0e-32	71.0
WP_011610705.1|1448618_1448921_+	2Fe-2S iron-sulfur cluster binding domain-containing protein	A0A222YX16	Synechococcus_phage	7.0e-32	69.5
WP_011610706.1|1449237_1449534_+	2Fe-2S iron-sulfur cluster binding domain-containing protein	A0A222YX16	Synechococcus_phage	3.9e-35	71.9
WP_155994306.1|1450073_1451690_-	SpoIID/LytB domain-containing protein	NA	NA	NA	NA
WP_044136401.1|1453071_1453713_+	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_011610709.1|1454097_1454445_+	STAS domain-containing protein	NA	NA	NA	NA
WP_044137179.1|1455459_1456593_-	SpoIIE family protein phosphatase	W8CYM9	Bacillus_phage	2.1e-12	29.9
WP_011610711.1|1456762_1457209_+	ATP-binding protein	NA	NA	NA	NA
WP_081432395.1|1457998_1458160_+	hypothetical protein	NA	NA	NA	NA
WP_011610715.1|1461791_1464824_-	PBS lyase	NA	NA	NA	NA
WP_011610716.1|1466316_1466853_-	translation initiation factor IF-3	A0A2L0UZ54	Agrobacterium_phage	8.4e-12	30.2
WP_044136410.1|1467121_1468048_+	alpha/beta fold hydrolase	NA	NA	NA	NA
WP_081432519.1|1469218_1469674_-|transposase	IS630 family transposase	NA	NA	NA	NA

Sequences of DBSCAN-SWA_3

Nucleotide sequences of DBSCAN-SWA_3

>NC_008312|1661571:1764252|DBSCAN-SWA
TTTACAGAGGATATTTCTCTACAGGACTTTGTCCATAAAAAGGTAATGCTTCTGACCAATGTGGTCTGTTTCCTTTTTGCCATTCTAAATGAGCTAATTCTAATAAACTTACAACATATTTTCCCAAGCTATTTTTAACCTGGATTAAATGATAAGAATTGTCCCAGTCTACTAACATTTTTTCCCATACTAGCGGATTCATTAGTGTATCTCCTGAAATAGGATTTATACCCATTTCTTCTACCTGATAAATAGCTGTAAATAATTGCCCTCTTTGAGCATGCATTTGTAGGAATAAATTATGACTTTTTTGTTTATATGACCAAGCTATAGTTGCCAAAGTTGAAATGGCAAATAGTGGTATATTTAATTGTTGAGCTAAAGTTCTAGCTGTGACTACACCAATACGAGTACCTGTGAAACTTCCCGGACCTTTAGCAACAGTAATAAAGCTTAAATCTTGCCATATTTGAGGTAGTATAAACTCTTGTAATTTTTGATGTAGGTTATTAGATAAATCTCGCCCTAAGTTCCAAGTTTGAGAGCGAGTATATTCATCAAAGTTACTAATAGCTAAACCTAACTCTGGACTGGTAGTATGAATTGCTAAACCATATTTTTTTTCCGTATTTGTCATTTGTTTGAAGGCAGAAATAAGAAGTTATAAAGAAGAAGAAAAGAGGAGGAATGGTGATTTATTTTTTAGTAAGAAAGTTATAGCTAAAGTCATAAAGTGAGAAGGGGTGAAGTCAAATTATTACTGTAGATAATTTTATGGCACTAACCCCAATTCAGAAATCAGAAGTTATTCCTAAATTAGTTTCAGCATTTATAAATATGCTAATCTATTTGCGTAGTTCTGTACTTATTAATATTCCCATCTCCCTATCAATTATGGGTAGCAAAAATTAAGCTATTTCTATTAGGTGAAGTATAGTTATGGTAGGCAAGATACCTGTATACTTATTAACTTATTTCATTTTAGGTTGAATTCAGGTAGGGATAAGTTCACCAGGTCTTAATTTTGCCCATTTGCCCATTTCTTCTAGAAAACTTTCACAACCGACAACATCCCATTCCATCTCAATTTCGTTTTGTTTGGGACGAATATTAACATTTATAGTAGGTTCAACTGGGTCAAAATCTGGATTTTCTGTTAAATGAAGTTGTTCGTGCTGAGTTTCTACAGCATGATAAGTCACACACTGATCCACATAGTGGCAGTTCACACAAATACACATTTTTAAATACCTCATTGATGGTCATTTTAGTTATCAGTTAATAGTTATCAGTACTTCTGAATGAAGCCAGGGTTTTGAAACACTGAAGTTTATTCTTTTCATCCCCTGAAAAAGGGAGGCTTGAAACCTTGTTTTTTTTGTTAAGTTTAATCTTAATTGATACAATAATTTTCGATCTTAATGGTTTGATAAGTTTATATTTTAACCTAAATTAATTTGATCTGGAATTTATAAAATCTTGTCCAAGAGAAAAAGTGGTTTTTATACTGATAAAAAATATACTTTTTTCAGAGATCATGTTAACTTTAACCTAGGTAAAATGGGATTTATATACCTAAACGAGAAACCGGGTTAATTGTCCTAATTATTGTTTTTCGCATGCCATGAAAAATTTTATCTCATAACCTGGTTTCTGGAAAAGTCCTATAAAAGTTTAACTGCAAAGAAATTCATTTTATTTTTGTGGCAATGTTGATAAATTCCCTGTCTGCTTTATCACCAGAAAATTGGCCATTTGAGGCAAAAATGCTGCCCCAAAATGTTTACTTAGTGGGTGGTTCAGTGCGAGATGCTTTACTGAAACGGAAGACTACATATTTAGATTTAGACTTTATTATCCTTGACCAAGCAGTTAGTATTGCTAGAAATATTGCTAAGGAATATCAAGCTGGTTTTGTGGTTTTGGATGCGGAAAGAAAAATTGCTAGGGTAGTATTTAAAGGAACTACAGTTGATTTTGCTGAGATTGAAGGTAATAGTTTGAAGGAAGATTTATGGCGACGAGATTTTACTATAAATGCTATTGCTTATAATCCTTTTACTAATGAATTGATAGATTTATTTAATGCTCTAAAAGATTTGCAAGACGGTATTATTAGAATGGTAAAATCTGAGAATCTTAAAGAGGATCCTCTCCGACTATTACGGGCATATCGTCAAGCAGCACAATTAGGTTTTATTATTTCCCCAGAAACTCAAACAACTATTCGAGAGTTTGCACCTTTAATTACTCAAGTTGCAACAGAAAGAGTGCAGACAGAATTAGGTTATTTGTTGAGTCATCCCCAAGGAATGATTTGGATAGAAAAGGCTTGGAAAAATGGTTTACTCTCAGATTATTTTCCTGCAGCAACAGAAAATTTGGGAATAGGAAAAAAGGTAGAGATAGTAGTAGAAAAATTACAAAAAAATTGGTCTACTTTAAAAGTAGAGTTAGGGAGTGGGGTGCGCAATACAGTCAAAACGTCTTTATTGGCAATTGCTAAATTAGCAATATTAGTTAATTCTAACCCACAAAAAGCGGAAGTTGAACTAATGCGGTTAAAGTATAGCAATGCAGAAATTAGAAGTACAATTGCAGTTCTTAAAAGTTTAGAAAAACTGTCAGAAATAGAAGTTCTTCATATGTCTGTTAGAGAACAATATTTTTTCTTTCAACAAATAGGAAAAAATTTTCCTGCTTTAGCAGTTGTAGCAGTGGCAAAAGGAATATCGATGGAGGAAATTAATTGTTTAATTGAACGTTATATTAATCCAGATGATCTAGTTGCTCATCCCACAACTTTATTGAGTGGAAATGATTTAATTACAGCTCTAAAATTACCTAAAGGTCCCATAGTTGGTCAGCTTTTAACTGAGATTCAAATTGCACGAGCTGAAGAGAATATTTTAACTCAAGATGAAGCTATTAAATTAGCACAAAAATTAATTGCATTCAGGAATGATCCTTCTTCTTTCTAAATATGACGTACTTTTTTATTGGTGGATATCTTTGTTATGAAACTACATTTATGAAAAATTATTATTTGCTCCAATACCAAGGTTGATCCATTAATTGAATAAATAGATTATCTATATCATTTAGTTAATGTTCATAGTAAAGGTAAATAGGTAAAATTAATTTTGAAAGCCAAAGTAAATATTATTTTTCCGAACTAGCATAACTCATAAATTTTAGTGCTGAATTAGCCAATAATTTTTTTTTTAATATTTGAAAGCGTTATGCTGATAATACTAATATTGCCCTAAAATACCCTATTATGGGAGAGTTATTTCCAGATATTTATGACCTTGTCAAAAATGTAAAATTTATATTTATTATTCAAGAACTACGAGATACTATTGTGTCTTTAATTAAAGTAGGAAATAAAATGGCTATTTAGGGTTAAATTAGGCATTTAAAACCGATGTTTACAGAAATAAAATAATCATAATTTATAAATTTTTATTGTCGTACTTATCCACCTTAATACAATTGTCAATTACTAGGTTTTTAAATAATGGTTGGTTATATCAAATATAAATTTTAGTACTTAATCCTGAAAGGAGAATTAAGCAACTTCAAGACTTTACTGGTTTAAGTTTAGGTAGCTTTATAAAAAATTATAAATGCCAGGGAAGTAAAATTAGTTATAGTCAGTTAAGTGATACAGAAAAACCTTGGTATTCATAACTTTATGGCAAAGAAATATTAGCTGTAAGTGTGGGGCTTTATCTTCAGGTTTTGCGAAAGGAATAAATTTAATTTATTCATAAAGAGGGAACAGATATATTTATAATTTTTAGATATTAAAAAGTAGCGATCGCCTTTCATAGCAATTAGAAAAAATAATCTGAGAAATCTCAAACAAAATAGTTAGAAATTTTTGCCGAGGAGCTACCTATATTTCTACGTGCCAGTCAAAATTCAACTTCCCTAACCCCCATAATACAAAATTAATCTATGAATGAGATTCATAATTTACTGATGTCTGTATCTCTAAAAATCTTCAAATTTTACGTGAGGAATAAATTAAGTTGCTTCAGAGAGAAGGAATAGAGAAGGAATAGAAAAGGAATAAATATGTTCAGAATTTTTCCTTACTAAAATCTAACAATAACTAGCCATAAAAATGATGAGAAATTATCCCACAAAAAGCATTGTTCTTATTCCCTACTTCAATACCTAATTTTGACTAGACTGCCAATTTTGATAAGTTTCTGTATCACTAAGAATATTCACATCAAATAAATCTATTTCCTCTTGCTCCAATAAAGCTAATATTGCCAAATTTAATTGGTCATAAGCTCTCGAATAATTGTCTAAATCATTAGTAAATCCAATTACTCTAATCACACGAGCATTTTTTTCTAATCCATTAAATCTCACGACACAAGAGTCATATAAAAGGTCAATTGATTTGGGAATTCCTCGAATTTTATCGTTAAGATAAGCTATCTTTCTAGCTGAAATTCCATCAATCTTGATATACAAATCAATAGCTGCTTTCTTCTTTTCATTTGGCTGTTGGGATAAATTTTTAATATTACCATCAATCATTTTAGAGTTAGGAACTTTCAGGGTAGCTCCCTCAAAACCTATATAAATTGTTGTACTTCTAATACCAATATGTTTAACCTCTGCCCAACGACCACTTGGCAATAAAAGCCAATCATCTATGCGATACAAACTATCACTATAAATTATAATAGTAGCTAACCAATCACCTACGAAATCCTTAAATAATAGACCTAATGTAAGACCAGCACCACCGATTAAACCAAGTAATGCAGTAGCAGAAGCTCCCAGTAATAATTCTGCTACTTTTAAACCAAATATTACGATGGCAGTTAATCTTAGTAGTTTCGGAATATAGGGGCTAATAATATCATCCAATTCAGTGTCTGTTTGAGCTGATAAAATTATAAAAAATTCTCCTAAAATTGGAGATATACGGTAGATAATTAGAGCGAAATTACCTACTATTGCTAAATTAATAATTCCTGTGATTGTTTGATTTAATTGTGGAGAAATATAATCTGTCAATATTAATTGTATTATCCACAATCCTAGTAAATAGATAAACCATCCAATAGGCTTTTTAAGAACTGCAATTAATTGATCATCAAGGGTTGTTTTTGTCTTACTAGTTAAAGCCTCAATTCGTTTAATTACAATTATGCTTAATAATCTTTTGAAGACTAATGTTGTTATTAGTACCAGGCATATAAAAAGTATTGTTATGACTGGTATATTCATAATTTTGATAGTTGTGATATTGTTGATAATTACCGAAATTGCTTCCATAATTGGCTAATAATAATTAGGTTAAAGTAATTGAAAAAGTTTGTAGTTTTTAAGTTAATAGTCAATGTTATTAATTAATAAGAAGGTGGTAGATTTAGGTAGAGTGGTAGACTTTTGTAATCTGGACCTCATTTCCTACAACCTACTCATATATTCAGAGGATAATCCCTATAACTTATAAAGCTTCATAAAGCTTAAAAATCAACTCTGCTCTTACCCCTGATCTGAGAGAACTCATCCATTTATAGGTTTATATAGGATACATTTTTTAATACTACTGTAATTTTACCAAATTATTTCACATATATAGCACTTTGCACGACTAATTAGTACAGGATAATAGTAAGTAGAATAAGTTCTAATTTGCTCAAAGTTTATGATTCCAATTATTGAGCTTAACTTTTATGGAAAGGACTGTATGTTTGAAACTACTTGTGATATTTTCTTACTTTTCGTATTACTAGGTTATAAGTACTCAGAGTTTAACTATAAACTATCAGCTTCATTAGTTTTAAATCTCAGAGTAAATGCTAATAGCTGAATGCTTAAGCTAGATTATAAATGTTTAATATTTTTGTAAGTAAATAGGCAAATTTATATAGTAAATTTGAAATTTGAAATATTTAATAATATTCATAACCAATTACTTGTAAGAATTTTCAATTTTAGAAAAATAACAATTTTATAAAACTTTAAAGTATGATATAATTAAAATATATTAAAAAAACTAAATAACTGTATAATTAGGTTGTTAATGCTAAAGAAAATTTTACCTACATATAGTGTGTTTTTATAATACAATTAAAATCTGTCACTATAGGTAGAATGCATTATTCGATGAGCCCTAATACTGAACCACAAATTAGTTATTTCCGAGAATGGACTAATAGCTGTGTTGATGACCAATTAATCCACCTTAACGTTGTCCCATTAGAAGGACAACGAGCTTATGAATTTTTATTTTATTCTGATGCTATTCCTCGACGAAATGATGGTCGAGTCACAAGCGAAATATTAAACCGATACCAACATATTGAAGAAGGTGGGTGGTGGTGTTCTGGAATTGATTTATTATCAGGAGAAGAAGATTTTTGGGGTTGTTTTAAACCTAGTCAACCACGTCATAGTTACGACGAAAAAAAAATAATTAAATATGAGCACCCTCCCAAAACTCCTACTAGTTTATTTGCTCTAAAAATTCCCCTACATTTATGGCATAAAATAGCGAGTCATTATCAATTAACAATTTTGCCAGAAGATATTGATAATAATCAACCAGACTTTGGTTTTTGGCAGTGGTTTATCGCCCATCCTCAAATACCTTTATGTATTACTGAAGGGGCAAAAAAAGCAGGAGCTTTATTAACAGCATCCTATGTAGCTATTGCCTTACCAGGAGTATTTGGTGGATACCGAGTTTTGAGAGATGAATATGGTAACCGTATTGGTAAACAACATTTAATTCCCCAGTTAGAAAAGCTGATTAATAATACTCGAGAAATTTATATTGCATTTGACCAAGATACTAAAGCTAAAACTATTAAAAATGTTAATGCTGCCATTAGAAAAACTGGATATTTACTCATAAAAAAGGGATGTAAAGTTAAAGTAATTTCCTGGAATCCAGAATTAGGTAAAGGAGTAGATAATTTAATCGCTAATCATGGAAAAAATGTTTTTGATGAAGCTTATAAAAAGGCATTACCTTTAGAACTTTGGAAAGCTAAATCATTTATTCGTCTCACATATCCGGTAAATTTGAGAGTTAATAGTCGCTATCTTTCAGAACAAAATATATTTAATTCTATAGACAATAATAACAATAACTTACATAAATTAGACGACATTGATTTAGATTATAGTATAAATTTTCCCGCTAAACTTATAGGAATAAAATCTGCTAAAGGAACTGGAAAAACTAAGTTTTTAGAAAAAATAGTTTCTGAAGCTGTAGCTCGTAATCAAAAAGTTTTAGTTATCGGGCATCGGGTACAATTAGTACAGGAATTATGTCAACGTTTTGGATTAAAATATATTACAGAAGTTAACTCAAAATCCCCAGATAAATTATTAGGTTTAGGGTTATGTATTGACTCTTTACATCCTAATTCCCAAGCTAACTTTAATCCAGAAACTTGGTCAGATGGAATAGTAATTATTGATGAAATTGAGCAAGTAATTTGGCATGCTTTAAATTCTAATACTTGTAGGAAAAGTAGAGTAAAAATTCTCAGATGTTTTAAAGCGTTAATGCAAAATATTTTAGGGGGTGCAGGTAAAGTATTTATAGCTGATGCTGACCTCAGCGATATTTCTATAGATTATTTACAAGCTTTAGCAGGAGTAAAATTAGAACCTTTCATTGTTCAAAATGATTGGTTACCTGGAGAAAAAGAAGCTTGGAAAATTTTTAATTACCCAGAAACAACTCCCAAAAGATTAATAGCAGATTTACAAAAACATATTCGTGAAGGTGGCAAACCAATAGTTTGTTTATCAGCGCAAAAACTGACAAGTAAATGGGGGACTCGTGCCTTAGAAGCTTATCTGAAAAAACAGTTTCCCAAATTAAAAATTCTGAGAATAGATTCAGAATCTTTAGCAGAAGTAAATCATCCTGCTTATGGTTGTATTAAGTCATTAAATCAAGTATTACTAAAGTATGATATTGTTTTAGCTTCTCCCTCAATTGAAACTGGAGTTAGTATTGATGTTCAAGGGCATTTTACTTCAGTTTGGGCAATTGCTCAGGGGGTGCAGGGAGCCACTTCTGTTTGTCAATCTTTGGGTAGAGTTCGTGAGAATATTCCTAGATATTTGTGGGTAGCTAATTGTGGTTTTAATCAGGTAGGTAATGGTTCTACTTCTATAACTTCTTTGCTCAATTCTGAGCAACGTTTGACTCAATTAAATATTCGGTTATTACAACAATCTGATTTTGATAGTTTAGATGATTTGGAAGTAGGTTTTCAGGCAGAATCTTTTTTGTGTTGGGCAAAAATGGCGGTCCGCTTTAATGCTGGAATGAATCAATATAGAGAGTCAGTTTTAGAATTTTTACGAATAGAAGGACAGCAGATCATAGAAGTTTCTGCAGAAGCTTTACCTGAAAATTTAGAAGAAAAAAAATCATCAGAAACTCCTGAAGAAATTAATACTTTGCAGGAAGCTATAGCTATTGTAATTAAGCAAAACTATCAGACAGAATGTGAGGCGATCGCTACTGCGAAAAGTATTAGTTTATTTGAGTATCAAAAACTCACAAAAAGATTATCAAAACCAATTCAACAACAACGAGAACAACGTAAATTTGAGTTGATGTTACGTTATAGTATTCCCATAACTGCTGAATTAGTTCAGAAAGATGATCGGGGGTGGTACCAACAGTTGCAATTACATTATTTTATGACAGTAGGGCGACCGTATTTACCAGCCCGGGATGGGGAAGTAGTAAAAAAATTGTTGGAGTTAGGTAAAGGTAATATTTTTATTCCTGATTTTAATGACTCTTTATTAGGTGCAATTATTGGAGTAATAGAATTATTAAAAATACCTTCATTATTGAAGGATAAAAAACGAGAGTTGAAAAATATAGACCCAGATTTACAATTATTAGGAAAAACAGCTTTGTCAAACCGAACAGAAATTAAAACTATATTAGGAATAGGATTAGCTGCTAACTCTAGCCCCATTATAATTGTTAGGCGTTTTTTGGAGAAAATTGGCTATAGTTTGGAATGTTTACGAACAGAAACTCACCATAAAAAACGATTGCGAATTTATCGAATTTTTCATCCTGATGATGGTAGGTTTGAAGTATTTCAGCAATGGTTGAGCTCAAGCCATAACTCAAAGGTCAGAACTTGTGTATAACAAATTTATACTCAACAAAGCTTTATTGTTTTTGGGTTATTTTTTGGGATATTCCTCCGTTTACTAGACCCTATTTACCCTTATTGCAGCATTTTAGATGTGTCATTCAAGAGTGTTCCTAGAAACCATGTTTGGCACAGAAACTTGTCATTTTAAAATTGGTAATTTGGTAAGTATTTATGCTGTTAAAATTTCTTAGAAAAAGATTTAGCATAAATACTTACTTAATTTTTTATTTCATGTTTACCATTATAATTTTCTTCTAACTTATAACTCAGAAACTATTTATTTAAGACTACATTATGTCTGCAAAAATATAGGCTATAATATTGTTAACCTCGAGTTTTTACTTGTAGTTGATGACTTATACCTAGAGTTATATTAGTCACATTATTAGTCACATTTTTGTTCCTGATGCCACTAACGCAGACATAGGTAAAATTAATGTATTTTTATCAACATAAGGTTGTGATATTTGATGAAAAGCTGCTTTAATATCTGCAATATTTTCCTGAGCTTGACTCCGAAGTAAAGCACCTGTTCTAGGAGCACCTTTATAGAAAGCATCAAACCATTCATCAGCATTTGCTAACTCCCAGGCCAAAGAAAATTTACTTACTAAAGGACTAGAAAAGCCAGCATTTTTTAATCCATAAATACAGTTTTGCTCTTCACTAAAATAAAAAAATGGAGGCCCTTCAGGCAAAGATACTTCTAAATTTCCATGAGCTTTAACTACTTCATAAACTAGCTTCATACCAATACATTTATCCATTATATCCCAAGCAGTAAAAGCAAATTTTCCTGCATAACGCAAAACTCTAAATGCTTCATTGATTGCCTTTTGAGGTTCAGCCAAATGTAAAATACCAAAATTCATCACAACAGCATCAAACTCTTCATTTTCAAAAGGTAAAAATTCAGCTCCTCCTTGAATAAATTCTAGGTCAGGATTAAGTTGTTTAGCCTTATTTAACATCCCATCAGAAAAATCTAATCCAATTACATTACATTCACGTTTAGCAGCATCTGTAGCTACATAACCAGGTCCAGTAGCAATATCAAGTATTTTGTTTCCTTTTTTGGCGTTGACAGCATTCAGAAGTGGTTGAATCATTTGATTAGTTAGAGAAGCAAAAGAACTATCGTATTGGTCTACAGATTTTTGCCACGCATTATATTCAAATTCTCTAAATTTTTTGATTGAATTACTCATTTTAGTTATTAGCTATTAGTTTGACTGCTGATAATTATCCAGTAAATTTTATAATATAATTTATTGACATTAATTCTTTGGTATCAATTAATAAAAGTAAGTTTTTTTAGATTGGAGCTTAGACTAAATTTTGGGGCATTTAAATCATCTTCTCAAAAAGTTTTGAAAACTTGGAACTTAGAAACCTTGGGCAATAAATATAAGAGGTGTAGATGTTTTCGTAATCAGTTGATTATTTTTCTTTTTTGGCAAGTTTGAATATTTTAAATTTATCCAAACTATTTAAAATATCTTTCCAGAGCATAATTAAAATTACCTTATAGTAAAACCTGTAGATAATTGACTGAAAATTCCTGACAATATTACAAAAGAAATAGTTTCCCTGAAGGTAGGCTTCTCTCACTCCAGTTTCCTGTGGTTAAGTTTTCAGGCACCAAGAATAAAGTCTACACTCCAGTTCATAATATTATTTAGAGAATAACTTGAACAATAATTCAACTCACTTAAGGTTTTTATTACAAGGGCTATAATATAAATCTTTAAATTAGCTTATTACTTTGTAAAGTTTTACTTATCAATACAAATATTGGCGTTGGTGAATCAACATAAAATCTAAGTTTGGCCAAACATAATTTTTTTTCAGTGAATAGTTAGGGGAGCGCCATTAAATGAGAATCAGGCGCCAAAATTACCAACGCCCAGATATTGTTACCCTCATCCCTGTATTTTTATATAGTAGAGTCTTTTATGTAATAAATGCATTTTAACAATGCATAAATGTCATAAAAGACTCTATTTTGTTATATAAGCTACGAATTCTTTATTTCCTTTCCTTTAAATTGATAAATCAAGAAATTCAAATAAAATTAGTTCAACATAATATGTATTCAGAACATTTAATCTTTTAAAAAAGTTTTTTCTTCTAGTAAAGATCTTAAAAAAACAAACAATTCACTAAAAATTAGACATAGAAAATATATAAATCAAGGAAAAGTAGATGACTGAGACTATACAGCGCAAAATGAAACTAAATAGTTTTGATAAATTTAAGGCAGAAAAAGATGGTCTAGCAGTAAAAACAGAAATAGAACATTTTGCTAAAATAGGTTGGGAAGCAATAGACAAAACAGACCGCAACCACAGACTTAAATGGTTGGGTGTATTCTTTAGACCTGTAACTCCAGGCAAATTTATGTTACGGATGCGTATGCCTAATGGAATGCTCTCAAGTCAACAAATGCGAGTCTTGGCAGGAATAGTCCAACGCTACGGCGATGATGGCAATGCCGACATTACCACCCGACAAAATTTACAACTGCGAGGAATTGCAATTGAAGACATTCCAGACATTTTCAATAGACTTGAAAAAGTTGGCTTAACCAGTGTTCAATCTGGCATGGATAATGTGCGAAATATCACAGGTTCCCCAGTTGCTGGCATTGATGCTACCGAACTATACGATACCCGTGAGTTAATCAAGCAAGTCCAAGACATGATTACTGACAACAATAAAGGCAACTTTGAGTTTACTAATTTACCAAGAAAATTCAATATAGCGATCGCCGGATGTCGTGATAATTCAGTCCACGCCGAAATCAACGATATTGCATTTATTCCAGCCTACAAAAATGATAAATTTGGCTTCAACGTTCTGGTAGGTGGCTTCTTTTCCGCCAAACGGTGCGAAGCCGCTATACCTCTAAATGCTTGGGTAGAACCCAATCAAGTCATTGCCCTTTGTCGAGCTATCTTAGAAGTATATCGTGATTACGGACTCCGGGAAAATCGGCAAAAATCAAGGTTAATGTGGCTTATTGACGAGTGGGGGCTCACAAAGTTCCGCTCACAAGTTGAGAAACAAATAGGGCTAACTCTAGAAACAGAAGCCCTCAAAGATGAAATTCTCTGGGAAAAGCGTGACCACATTGGCATTTACAAACAAAAACAACCAGGGTTAAACTACATTGGGTTAAATATTCCTGTTGGCAGATTATATGCTGTCGATATGTTTGACCTAGCTCGTTTGGCTGAAGTTTATGGCAATGGAGAAATCCGTTTGACGGTAGAACAAAATGTCATCATTCCTAATGTTCCTGATTCTCGGCTGGAAACATTTAGAAGTGAACCCCTCCTGAAAAAATTTTCTTTTGAGCCTCAACCACTAACTAGAGCTGTAGTTTCTTGTACAGGATCACAATTTTGTAACTTTGCCTTGATAGAAACTAAAAATCGCGCCTTAGCAATAGCAAAAGAACTAGAAACGGAACTATCAATACCAAAACCAGTACGCATTCATTGGACTGGTTGCCCCAACTCTTGCGGACAACCACAGGTTGCAGACATTGGTCTGATGGGCACTAAAGTTCGCAAAAACGGGAAAATGGTCGATGGTGTTAATCTATATATGGGTGGGAAAGTTGGTAAAGATGCTCAACTTGGCAGTTGTGTTCAAAAAAGTATTCCTTGTGAAGACCTCAAGCCAATATTGCGGAGTTTGCTAATTAAAAATTTTGCTGCTCAACCAAAATAAGTCTGTGCTCAAAGTTATTGAACGAGTACACAGAGAGTTATTCAATTCTTACCCAGTAGTACCATCCTGCTTGATGTAAAGGATAGGTTATGGCTAAGGCCATGCTCCAAATTTTCCTTTGGTTATACTGCGTCAATTAAAAAGCGAAAATATCAACATATCATCAACACTGGAAAAAATTAAAAAAATAGAATAAAATAGATGACAGTGTTATTGATAAGGTAAGAAAAAGATGATATTGTATATGGTATTAGTACAGTAGACATTAGAAAAAGTTGTTAATAAACAAAAAATAATAGAAATAATATTAACAACCAGACCTACTCAAAAAGCATTTTCATTTTGATTTCATGGGGGCATTTCAGCTATAACATAGCTTTGGACCATTTCTGCAATTATCAATAAAAGTATGTTAACAAAACTCTGGTCTTTTCGCGGTCGTTACCGCATTCTCCATTTAACCTGGTTTGCTTTTTTTCTCTCCTTTGTTGTTTGGTTTAACTTAGCACCATTAGCAACAGCACTAAAAGAAGACTTAGGTTTAGAAACTTCTCAAATCAGAACTATTGCCATCTGTAATGTAGCACTCACAGTACCTGCCCGAATTATCATCGGAATGCTACTAGATAAATACGGACCAAGAATCACCTATTCACTCTTGCTCATGTATGCAGCCATTCCCTGTATTGGCTTTGCTTTAGCCCAAAACTTTAGCCATTTGGTAATCAGTCGTTTGGCATTAAGTATTGTAGGTGGTGGTTTCGTGATTGGTATCCGCATGGTAGCAGAGTGGTTTCCCCCTAAAGAAATAGGTTTGGCAGAAGGTATTTATGGCGGTTGGGGTAACTTTGGTTCTGCTGGCGCTGCCTTTACACTCCCAACTATAGCGGCTTGGTTAACTTTTGGTTCAGGCGATGTCTTAAATTGGCGGGTATCGATCGCTCTGACAGGTATTATTGCTGCACTCTATGGTGTGTTTTACTTCTTTAATGTTCTAGACACTCCTCCTGGTAAAACATATCAAAAACCGAAATGTGCCAGAGGCTTAGAAGTTACTACCCCAAAAGATTTCCTTTTTTTGGTTTTGATGAACATTCCTTTAACAGGAGTTCTGTGTTTGTTAGGTTGGCGTTTAAGTAAAGTAGGTTTCTTATCCACAAGTCAACTTTATATTGTCTGGCTAGTGCTATTAGGTTTATACGCTTTCCAAACTTATAACTGTTGGATAACCAACAAAGAGTTAATTGCTCAAGAAAAACACTATCCCCCTAGCGATCGCTATAAATTCTCTCAGGTAGCAATTTTAGAGTTAACTTATTTTGTGAATTTTGGTTCTGAATTAGCAGTAGTTTCTATGCTGCCTGCTTTCTTTGAAAATACTTTTGGTCTTAGTAAGACAATGGCAGGAATGATTGCTGCTAGTTATGCTTTTATGAACTTGGTATCTCGTCCTGGTGGTGGTTTAATTTCTGATAAGTTAGGTAGTCGTAAATTAACAATGACAGTATTGACTGTAGGGATGGCGATCGGCTATTTGACAATGGGTAACGTTAAAGGAAGTTGGTGGTTGCCTGCAGCGGTGTTGCTAACGATGCTTTGTTCTTTCTTTGTTCAAGCTGCAGAAGGTTCCACTTTTGCCATAGTTCCCCTAATAAAACGGCGAGTGACTGGTCAAATAGCAGGTAATGTAGGTGCTTATGGTAACGTAGGAGCAGTCTTATATCTGACTTTGTATAGTTTCCTGCCTGAAGGTGCTATTGGTGACAAGATTTTCTTTGAAGTTATTGGTGTGACATCAATGATCGTTGCTTTCATCTGTGCATTCTTTCTCAAAGAGCCAGAAGGTTCATTTGCTGAACACCATGAGGGAGAAGAGGAAGTACAGATAGAATCTCATACCTTATTCGCTGAGGAATAAGATTGAAAAGCCTTAATAAAAATGGGTTTTAGCGATTTTTATTGCCTTGTATTTACTGACATTTTCTCGGTTATGCTGCACCCTTGAGGTATTTTTTACCCCAGAAAATTTGTAAGTACTATTAGTAAGTTTCCAAAAAATTAAGTGCACTATGAAAACTACAAAAACTGCTTGCCCTTATTGTGGCGTAGGCTGCGGATTAGAAGTATCACCACCAGCAACCCCAGGAAAAGTAACAAATCGCGATAGTAAAGGTAATCCAACTTGGCAAGTACGGGGCGATCGCTCTCATCCATCAAGTCAAGGCAAAGTTTGTCTCAAAGGTGCTACCGTTGGCGAAGCATTGGATAAAAGTCGCCTTAAGTATCCAATGATGCGCAATACCCTAGATGAAGCTTTTCGTCGTGTTACTTGGGAAGAAGCCTTTCGGCGCATTGTTAACCAAATTCAAAAAGTACGTTTTTCTCAGGGACCAGATGCAATTTGTATGTATGGGTCTGGTCAGTTCCAAACAGAAGACTATTACGTTGCTCAAAAGTTGCTTAAAGGATGTCTGGGAACTAACAACTTTGATGCCAACTCTCGCCTCTGTATGTCTTCAGCAGTATCTGGATACATTCAAAGTTTTGGGTCTGATGGTCCTCCTTGTTGCTACGATGACTTAGAAAAGACAGACTGTGCATTTTTAATAGGTACTAATACAGCCGAATGTCATCCTATTATCTTTAACCGTCTCCGGGCATCTAAAAAAAGAAATAAAAAAGTCAAAATGATTGTGGTAGACCCCCGTCGTACCAAAACCGCAGAAGTAGCAGACCTACATTTGGCAATTCGACCAGGTACAGATATTGACTTACTTAATGGTATAGCTAATCTGCTCATACAGTGGGGTTTACTGGATGCAATGTTTATAGATGAGTGTACGAAGGGCTTCCCTGAATACGTAAATATCATTCGTCAGTATCCACCGGGGCTGGTAGCACGTCATTGTGGAATTCGCTTGGATGAGTTGGAAACAGCCGCTCGTTATTGGGGAAAATCCGAGAGAGTTTTATCTTTGTGGTCAATGGGGATGAATCAGTCATCAGAGGGTACAGCAAAAGTGCGAACCTTAATTAATCTTCATTTAATGACAGGTGATATAGGCAAACCAGGCACAGGTCCGTTTTCTCTTACTGGTCAACCAAATGCCATGGGTGGAAGGGAAGCAGGTGGACTAGCTCATCTTTTGCCTGGTTATCGAATGGTAAAAAATTCTCAACATCGTGCTGAGGTTGAAAAATTGTGGGAACTAACTCCCGGAAAAATTTCTGATGTACCTGGTCGCAGTGCTTGGGAAATGATTATGGCTTTGGAACGCAAAGAAATTGGTTGTTTGTGGATTGCGGCCACTAATCCTGCTGTGAGTATGCCTGATTTAAAACGGACTAAGGCTGCTTTGTTGCGATCGCCTTTTACTATTTATCAAGATGCTTATTATCCCACCGAAACAGCTGAATATGCTCACCTATTATTACCGGCAGCTCAGTGGGGAGAAAAAACAGGCACTATGACAAATTCGGAGCGAGTGGTGACTTTGTGTCCGGCATTTCGTGAACCTCTCAGAGAAGCTAAAGCAGATTGGGAAATCTTTGCCGAGGTAGGTCGCCGTTTAGGATTTACAAATCACTTTAATTTTGCTGACTCGGAAGCTGTCAGAGCTGAGTTTTTGGAATTGACACGGGATCGCCCCTGTGATATGACAGGCATTACCTATCAACGACTCCAAGAAAAAGGTCCGACTCAATGGCCTTGTCCTGATAGTAGTGGCGTATCTCAGGAGCGTCTGTATACTGACTTTCGATTTAATACTCCCGATGGCAGGGCGAGGTTTGCAGCATATTACTCTCAAGGACTAGCAGAACCACCTAATCCTGATTATCCATTCATTTTAACAACTGGACGATTATATGGTCATTGGCACACTCAAACCCGTACAGGGCGTATTGAAAAAATTCGCAAAATGTATCCCCTACCATTTATGGAAATTCATCCCCAGGATGCTCAGAGATTGGAGATTTCAGATAATGATTGGGTAGAAGTAAGGTCGCGAAGAGGTTATAGCAGATTTCCAGCCAAAATCACCAAAGCTATTACTCCAGGTACTGTATTTGTACCGATGCACTGGGGTGCATTATGGGCACATCAGGCAGAGGCAAATACTCTGACTCATCCTCAAGCTTGTCCTGAGTCTGGACAACCAGAGTTAAAAGCTTGTGCTGTACAGTTACAACCAGTTAAATTTCAAGCAGCTCCTATAGCGCTATGGGCAAGTAAAAAGTCAACCCCCTTGGGAGAAGTAAAAAGCTCAAAGTAATTTCTATTTCCTGTTTCCTAATTTATCCCTATTTCCCCACCATCCCACCTCTCTCTACTTTGGAGTGTTATAAGAAACCAGATTTATACAAAACAATGATTCCCTATTATTCGGAAATGATAGTCACCCCAGACTCAAAAAGGTTAATGTGTATTAGGGAATGACATATTTTGTCATAGCCCTGTTGTTTTGATGTTTTACAAATATCATGATCAAGTCTTTTAAAAAATACAGTTAATTCTAATAGAACCCTGAAATCATTAATATCAAAACCTTGAAATACCTGTATAAAAACTTAGTTTTCCCAAGAAGATGTTTAATATTTTTAATCTGCTTAATTCCAAAGCTTTTTCAAGGGCTTCTTTTTTTTATTGTTATTTTAAATGAGGAGAATGATCGTAAGTTCCAAAAAGAGACAAAGTAATGATAAGTCGATAGTTATACAATTTTTGCTTCACAGAACCTGAACGTCTAACTAAGATGATGTTTTGGCTTTGGTAATTTTGGCGCGTAATTATTCTTGAATTGCGATCGCCAAACTATTAACTAAAATTTTTTTTATTTTTGCCAAATTTAGATTTCATATTGATTCATCAACACCATATTTTTCACATTGATAAATAGTTGAGTTTCCTCAAAAGTGTTACTGTTTATATGGCTAATACTAGCGGCAAAAGTAATTTGATTAAAGTCATGAATTTTCAGGCTTGGTTTATGCTCAATTCACCAAAAGAAACTCATAAATAAGAAAAATTAATTGCTGATTAAACTAGATAAAATACACTATTTCTTTCTCTAAATGCTCAATTTAACCGCCAAATCTCTACAAGTATTTTCCTCTGGTTTCTAGAAAGGATATAATTTATTGGCGAGGTTTTCGTAAAAATACGATTTCTTTAGTTACAGAAGATTTAAGGATTAAAGAATAAAATAATGACTATGATCAAGTTGTGTGTATATTTGACCGTGATTCCTTTCTGGTAGAAAATTTTAATCAACCCATCAAATATGCTCAAGATAATAATATTAAGGTATCATATTCTAATTCAACTTTTTAACCTTGGTATTTGTTACATTTTGATGATTGTAATACTGCAATTTATCCCAAACCAGATAAACAACTTTTAACTTAAAAGTATGAATAAAAAATATGCTAAAAATAGCAACACAATATGTGAAAATAGTGCCTTTTTCACTCCACAAAAGTACCAGCTTTTGAGTAGCTTAAGATCATGTATATTAGTATTTTGGCCAAACAAAAACAGAGAAATCAAAGGACAACTCTGACTCCTACCTCGTAATTAATTTCTATTTATTCCTAATTCCTAACTTCACTCATAAGACTTTTTCCGTAAACTCTAAATAGGTGTGAAGCGATACATTTTCATCCTGTGAAGCACCACAAAAAATTTGCATCAATTAAGCTGGCATTCTCAAAGCAAATCTGATACTATAGATATTAAAGTACTTGCTTGCACATAAGCTAGATTTTTTATTCAACAAAAAAAATCTAGGTCAATTACCAAAAAATTGAGTCTAAAGCCTTGCCCTTTTGGGGTGACTGTTTAGTTATTTTTTTGAATAATGATTTTTTTTGATTCTGGGTGCTGACAATTAACTGTAAGTTATGGTTTATATATGGAAATGTTCATTAACATACAGTGTATAAATTTTTGATTAAAGGCAGAATGCAGAAGGTAAAAGTCAAAGAGCAGAAGTTTTTTTTAGTTATGAAGTAAAAACCGCTATACTTCTTATAAAAGTTATTAGATTAATTTTAAATTCGTTCAAGTTACTACATATAAAATTATCATTCTTGGAATTACTGAAAATATTCTTCAAAGCCCTATTGGATATTAAAGTTAATTGTTTTGATAAAATATCCTGAAAAAGCCCATAGTTAAGCTTAATAAATTTATATCTTACTTACTCAAAACTAAGAAAAACCATATTATTTTGAGCACTTCAAGAGCCAGAAATTATATAATTTATAATAGTAAAATTATATCATAATTGTCATCGTGGTTCCAAAAGAAGCCACAAACTTTATAAACAAAATAAATTTATTCACAATAAATGGGAATTCATATCCTCATATTAAACTATCATATTCATAATCTATACAGATAATTAAACCTGCTAGTAACTCTTCAAGAATAGAATTTGAAACTCGCCCAAGACATCTCACAAATCTTTCATTAGCAATACTACGAACTTGAAGCACATTACCAGCAGAATCGTTATCTAAACCATTTTCATCAGTTTTCGGTATCGAAATCATAAATAGACGGTTTTTAAATTTAGATTGCCATTTAGCTATAGGAACAATAATTTTAACACTTACTGATCTAAAAATGTTTGAACTAATCACAATTGCTGGGCGAGTTTTTTTTATTTCTTGACCTCTAGTAGGGTCTAATTTTACTAACCATACTTCTCCTCTTTTAGGGTTATTCATCTCCTGTTTCCCAATCTTCTCCATCAAGAATAAAAAACTCTGTTAATTCTGGATCATTCAAAAAATCTTCAGCAGTTTTATCTATTGATGGTGTTAATAATTTATGACGCTCTACTATAGGTAAACGGGCAATTTCTTTAAGAGATAACTGATTATTATAATTAACTTGAGAGTGGTTCAATTTATGTTGAATAAACTGAATAAAGTCTAGTACTTCCTGTTGTTTTTCTGGTGGTAATAATTTAAGATTATCCAAAATTACTTGCTCAATATTATTATTTGTTATTGTCGTCATAAAATCCATCTCCAACTGATAGAAAAAAGTGAGCATATTGTCTACCCCAAATTCAACTATATCAAAATAGGCATTCAAATATTTGGCCATAGAATGATAAGTGATGATCGCTGTTTTAGACTTTTCTAGACAAAATTATTCCTTTGCATTCTGATGCAGATTAATTTTTTTAGTCTGTAACAAGTCTAATTTTTTGAACTGCTCCTAAATATTGGGGCAACTTGGATAACTGAAAACATTTATCAACAAGCCAAAATATTGTCAATTCTCTGCAATACATCATTAGGGGCGTTTGAGGACAGAACATTATTTCGATAACTTCATGTTTATGGTCAGGGAAATTTAACAACTTTAGCTTTTTATGATACCTCGTATTATCATAGCGGAAAATCAGGTTATTTGAGGTTAGTTAACTATTGTTGAAGATCTAATGTTTATTCACCATTAGTTTATATATATTGATCTAATTATACTGAATCAAGTTATATAAATTATGGTAAAATCATACAAACAGACTAATTTGTGGCGTCAAACCAGCCCACCGCTTAACCGAATTCTTGATAAATTACCATTTGTCCTATATCAAGTCATTGAAACTTTTGTGAATTTCGATCCACCAAGGGGAGGCTAGTTCTTAAAAGCGTCTAGAAGTTTTCTTATAGACATTGGGAGATATCCTCTCAGTCGGTCAATGTTGCTGTGGGTTGAATTGTTAGCACTCATAGTATTAGCTGTCTGATATTGATAAGAATATATAAGCACTTAAAACTTAATTGTTTACCTAACCTAGTTTTATATTAAATATGCAATATAAGAGATTAAGCTAAAAAAAATGTGCCATTAATTTTGTCAAGCTGCTTATCACCCTCTACAGTTATTTTTACATCTAAAAACTCGTAAAAGTAAAGTATTGAATTGTGTTTAAATCTAACTTTTCCCGGAAAAACTTTTATCTGCACTTTATTTTTAGGAATTAAATGTAAAATTTTGAATAACTGAAAATGTCTGAAGATTTTTAGCTACTTAATAAAAATCTTGTTGGATAAGCAAAATAAACTGATTTATATATTTATAATTTTTGATAATATCGTTCTCTCATTATTGATTATGTAATGTATTTATATAACTCTCAATTTTCTGAAAATTTATCATTTTATTATATTTTTATAATTCCAACATCTGCTGCCTATTCTTAATTGTAAATATACAATTTTTTGCACCATTAAAACATAGTTATTTATATTTTTTTCCTCGAATTATGCCTTTAAAATAACTTCATTAAGAGACTATCATCTAAAAATTATGTACTATTTAATAAAGTACTATTAAGTCGTGAAGTTGCTGCAAATAATCTTTAAATAACAAATTCAATATATCCCAATTTTTCGGTATTTTCTTCCAGTAGTTTCAACATCAAAGCTTCTCCTATCCATTCATCTAATTCTAATATTTCTTCAAATTAATCTTATAAGAGTATTTTTTTAGTTTTAGTAATTCCTAATTTTAGTAATTTTACTCGGTCAGAAATAAGACTGTCAATGTTATTTGTTAATGATTATGGATACTGGAATTTAACTTTAAATTCTGGCATGTTTATTATCTCCTTTGAAAGTCAGTGTAGGTTGGGTTGAAGGATAGTAAAACCTAACAAAGTTTTAGTATTATTAGGTTTTGTTTGGGTACCAAACCTACGCTTAAAAGATAACTAGTATCCAAAAAATAGACTTCTTTCATATTATACAAATAACGATCGCGATCGCTTACAGTATCCTTTACATAATATTCCACAGGATTTTTATATAAATCTCAAATGGAAGGTGTTTTTTAATGCTGATGATAATAATTTTCCCATTTTCTTGAATAACCTCAAATTATTAGCTTTCTCCTCATAATTCTTTAGGTATTAATAAACCTTGTTCTGTTGCTGTTAATTTTATGTTTGATTACCCTCATTAATTTTGTAGATTAATTCATGAAGATGACTTGATATCAAATATTATGAGAAATTATTCTGTAAATAACTGATATTTGGTCTCAAATTTCTGCAATTTTTTATTTAGTTTATTCAATACCATCAGACAAAAACTGTAACTATTTTTCTAATGCTGATTTTCAAAAGGTTATTAATAATTCTGGGTGCAGGTATTTAATTTTTAATTCTAGCATATTTATGAGCTCTTTTAAAAGTAATCAAATTTAAGATTTCTAGACATTGACAAGATAATAAAGATTAGTAATTTCTAGATTAATTTAGACAAGCGATCGCTCCTCCATTTCACAAAAAAATGAGGAGCGTCGCTATTTCTGTGTGAGCATATTGCCCACCCTAAATTCAACTACATCAAACTACGCACTAAAATACTTCGCCGCAGAATGATAAGTAACGATCGCCGTCGTAGACTGTTCAGGATACAACTGCTCACTCTCATCCATATACATATCAATTCTTTTAGTCTCCAACAAATCTAACTGCTTAAACTGATCCTGCATATTCGGACAAGCAGGATAACCAAAACTATAACGTGAACCTTGATAACGCTGTCTCAGAATATCCTTAATATTATCCGCATCCTTACTACCAAAACCCAACTCCCGACGAATACGAGCGTGTAACCACTCCGCCATCGCTTCCGCAGTTTGTACCGCCATACCGTGGAAATACAAATAATCTGTATATTGATTATCTGCAAACAATTTCTGAGCAAACTCAGTCGCTATTTCTCCCACTGTCACAGCGTGCATCGGAAACACATCAATAACTCCCGACTCCTTAGGAGCAAAAAAGTCAGTAATACACAACCGTCGCCCTGACTTTTGCCGTGGAAACTCAAAACTGTTGACAACTTTTGTTGCCTTTCCAGTCTGACTCATTTCCTCCGAGTCGTAAATTAAAAGTGTATTGCCTTCTGCTTGACAAGGGAAATAACCATAAATTGCTTGGGGATGTAGCAACTTTTCTGTAATTACCCGTGACTTCCAGGTTTCCAGAATAGGATAAACTTTCTCAGCTAAAAACTCATCATACTCTTCCCGCGACTGGTCTTTAGGTTTACGGAATTGCCATTGCCCCGCTATCAACGCTTGCAAATCTAAATACCAGAATAATTCCTCAAATGGCATATCCTCTGGTTGTAATAACTTGGTTCCCCAGAAAGGCGGAGTCGGGCGCTCAATATCAACTGGCACATCATCAGAACGTCGAGTATCTACTGGAGCAGCAGTTTGACTTTCCTCTTGATCTTCAGACTTAACTGAAGTAGCAACTTTACCATTACCATTACCATTACCATTACCATTACCATTACCATTACCATTACCATTACCATTTTCTTCCGCCAACTCATTTAAAAACCCTTGGATATCATCCCACTGCTTTTCTGCTTTTGCTGGCATTAACTTATCCATGAAATTCAAATCAGAAAAAGCATCTTTACCATAAACAACCTTACCTTTGTAAGTATTTTGGCAATCTTCATGGACAAACTTAGGAGTTAGTGCTGCACCACCTAAAATCACCGGAACAGTAATACCTTCTTGATTAAATGTTTCCAAATTATCTTTCATAAATGCAGTTGACTTCACCAATAAACCACTCATAGCAATACAGTCAACATTATGTTCTCGATAAGCAGTAATAATATTATCAACTGGCTGTTTAATTCCTAAGTTAATTACCCGATAACCATTATTTGACAAGATAATATCCACAAGATTTTTACCAATATCATGCACATCTCCCTTAACAGTAGCAATAAGGAAAGTTCCCTTAGAATTATCTCCTGACTCTTCCTTTTCCATATAAGGTTGTAGATAAGCAACAGCTGCTTTCATAGTTTGAGCAGACTGTAATACAAATGGTAATTGCATTTGTCCAGAACCGAATAATTCTCCTACTACTTTCATGCCATTTAATAAGAAGACATTGATAATATCTAGTGGCGGATATGTTTCTAAAGCTTTTCTCAAAGCATCTTCTAAACCAATACGTTCCCCATCAATAATATGTTGTTTTAAACGTTCTTCAATTGGTAAATTTTCTGTAGCAGAACGGTCTTTTTTAGTCGTTTTACCCTCAAACATTTTTGTCAATTCAGTTAGAGGATCATAAACACAAATATCCCCTTCAAATTGACGTTGGTCATATATTAGTTTCCGACAAATATCTTGATGTTTTGGTTCAATTTTTGCTAAAGGTAAAATCTTATTTGCACTAACAATTGCACCATCCAGCCCTACTGCCATTGATTCATGCAAAAACACTGAGTTCAACACTTGTCTAGCTGCAGGGTTTAAGCCAAATGAAACATTAGAAACTCCGAGCATTATATGACAGCCTGGCAACTCTTCTCGGATCCGTTTAATAGCTTCAATTGTTGCTTTTCCATTCTCCCTATCCTCTTCAATACCTGTAGAAATTGGCAAAGCTAGGGTATCAAAAAACAATTCACGGGCTGGAATGCCATATTCTATTGCTGCATCATAAGCTCGTTTAGCTATTTCAAATTTTTTGTCAGCTGTCCTAGCCATTCCATCTTCATCAATAGTTCCAACTACTACACCAGCACCATATTTTTTCGCCAATTCTAATACTTGATAAAAACGGGGTTCTCCATCTTCATAGTTAGTAGAATTAAGCAAACATTTACCACCAGCAACCTTTAAACCAGCCTCCATTTTTTCCCATTCTGTCGAATCTAACATCAGAGGCAAATTAACATTTGTGACCAAGCGAGATGCTAATTCGTGCATATCGCGCACCCCATCACGTCCCACATAATCAACATTAACATCAAGTATTTGTGCCCCTTCTTTTACCTGAGATTTTGCTAGGGCAACTAAGCCATCCCAGTCTTCATCATTTAGTAAAGTTCGGCATTTTTTAGAACCGCTAGCATTCAGTCTTTCACCAACAATTAAGAATGAGTTATCTTGTTCATAAGTTTCTGAAGAATAGATAGAAGCTGCTGCCGGAATATAGTTAGGTTTTCGTTCTTTTGGTTTGAGGGTTTCAGTAATTTCAGCTAATGCTTTAATATGGTCGGGGCGAGTACCACAACAACCACCGATGACTTGGACTCCTAAGTCTTCAACGAAGTGCATTAATGCCATTTTTAACTCTACAGGAGTTAGTTTATAGTGAGCTTGTCCCCCAATATTTTCTGGCAAACCAGCATTAGGAATACACGAAACAATAAAAGGCGAATTTTCTGACAAATAACGAATATGTTCTTTCATTAAATCTGGGCCTGTAGCGCAATTTAATCCCAGAATATCAATAGAATAAGGTTCTAAAATTGTCAGAGCAGCATTAATTTCTGAACCGACTAACATAGTTCCAAAAGATTCCATTGTTACTGATACCATGATAGGTCGGCGATCGCCTTTTTTCGCAAAGATTTCTTCTATGCCATTTAAAGCAGCTTTTATTTGCAAAACATCCTGACAAGTTTCGACAAGAAATAAGTCTACTCCTCCATCAAAAAGACCTTCAGCTTGTTCAGTAAAACTATCTTTTAGGGTAGCAAAATCAATATGTCCGAGGGTAGGTAATTTTGTTCCTGGTCCAATTGAACCAGCCACAAATCTAGGTTTTTCTGGGGTAGAATATTCAGCAGCAGCAGACTTGGCTAATTCCGCTGCTGTTTTATTCAGATAATAAGCCTGGTCTGCTAAGTCATATTCTGCTAAAACAATTTTTGTCCCACCAAAAGTATCAGTTTCTATCACATCCGCACCTGCTGCTAAGAAATCTCGATGAACTTTGGCTACTGCGTCTGGTTTAGTATGGACAAGATATTCATTACAACCTTCATATTCTTTTCCGCCAAAGTCTTCTGCTGTTAGGTTTTGGACTTGTAAGCTAGTACCCATAGCACCATCAAAGACGATCACTGGGCGTTCTGGACTATGGAGACGGTTTAAAAACTGGCTGTTCATCATCGTATATTTAATATTTTAGTGTTAGTATTTATACTACTATTTTGAGAGGTTCAAAGCAATTTATTTTTCAAATTATAATATAGATTGTATTGTGTTTATCAATTAAGTAGAAATAGAATCAAATCATAGAAACAGATTTTATCATTAAAGGGGTTATCTGTTAACTACTATCAGCTCTGGTGTTGCTATTCTCATCATTTTTCTCTCACTTTAACACAGTTAAATAATAACTAAAATCAACTTATAACCATTCAAAAAGTCATCGAAATATGCTAATTGATTATAACTTCTATAGTAATCCTAAATCATTTATGAAAAATTACTAGTATTTTGAAAAATAGCTTTAACCACTCTTACTTTTGGTTTCTCTATTCAGCATAAATACATTGTATTCGTTCCTCTCTTTCACTTTTCAGATAGGATTTTTATCTAAATTCTATTATCAATAATTACTAATTAATTAACATGCTGTATTTATGCAATAAATTATTCTACTTATTTCTTCCAAAGAATAATTATAGACGATCAATTATTTTGTATTTAATCTCTTGATTTTTTTTATGGGATTGCAACTACAACTTTATCCGTAAAGTAATTAAATACAATGAAATTAAAGTAATCATCATTAATAATAGCCAATAAAAATAATCTTAAAAAAATACGGCATTATTTAATATGAAAAATGAAATATAAATCAATCAACTAAAATGTCAAAAAAAAAATGAGCTCAATAGAATGCAAAAAAATAAAAAATAATAGTAATAAAAAATATCAAATAGCCTATAAAATCATGTAAAAATAGTTATTTTTTAGTGGAAATATAATAGTTATTATTTATGCTGTTATAGCTATAAAATTATTTAATTTTACATTTGATAAAATTGTTTATACAAGGTTAATTACACATTTATAAAACCTAAATTATTTGTTTTATGAAAAGCATAAATGATTAAAATCGGCAAATAATGCTCTGAGGTACTTAACTTGAAAATACAAGTTTTCTTTAAAGTACATATAAGAGCTAATAGTATTAATCAATGGCTTGTTAGTAGAAAATTGGAAATCCAAACTATAGAAAATACTTCTACCTTCCCAACTATGAACTGGTCAATAGTTACACCTTTCTTAAAATCCCAGCTCATGGAATAGCAAAATTTTTTTTACCATGATTAATCCTGATTTTTATTAAAATACTAGCAAAGTAAACCAAGATAAAACTAATCTCTAAAATTATAAGTACATTTGAAGTAGAATATTTTCTTATAAAATTTTCAGTAAAAAATAAGGGGTAAATTAATGACAAAAAAACTAAATTCAGAGCATATTTTAGTTGTAGATGATGTTCAAGCTAATCTTAAAGTAATAGTTAAAACTTTAACTAATGAAGGATATAAAGTTTCTACAGCAATTAGCAGTGACCAAGCGCTCAAGCAAATTTCCTATGACTTACCTGATTTAATTTTGCTAGATATACAAACCTCTGGTATTGATGGATTTGAAATTTGTCAAAGGTTAAAAGAAAATCCAGAAATGAAAGACATCCCAGTAATTTTAATGGCTGTTCCTTCAAACATTAAAAATATAGTTAAAGGTTTGACATTGGGAGCCGTAGATTATATTACCATACCATTTCAAACAATTGAAGTCCTTAGTAAAGTAAAAAATCACATACATTTACAACAGTTAAAAAAGAATCTCGAAAAAGAAGTAGCTAAGAAAACTTATGAACTTACTCAAGCTTTAGAGCAGTTAAAAGCATCTCAAGTCAAACCCATTAAAAGTGAAGAAATGTTAGTAACGGGAGAATTAATGGCTGGAGTAGCAAATGAATTTAATCACCCCATTGGTTCAATTTATAGTAATTCTTTTTATTTAGAAACATACATAAAAAATATTTTGGAACATCTATTTCTTTATCAAAAAAATTATCCTAATCCTGTAGCAGAAATTATTCAAAGTGCTGAAGATATTGATCTAGATTTTATTATAGAAGATTTCCCTAATATAATTACTTCTATAAAGACGAGCTCAGAAAGGATTAAATACCTGAGCTCATATTTACAAAAATTTCGTAAACAAAGTGTTATTACAGCCCATAAAAGTATTGATAGTGCTCTATTAATTTTGAAGCATCGCCTCAAAGCTAATCAGTATCGCTCCGGTATTAAAGTAGTCAAAAAATATGGAGATTTGCCTAAGATGAAATGTCTGCCTGGACAATTAATTCAGGTATTTATGAATATAATTTATAATGCTATTGATGAGATTGATGAGTTTGGTAAGAAAGTAGGTTTTTCTAATTGTAAATTTGAGCCTAAAATTGTAATTAATACTTTAATGAGTCATGATAAAAAAGAAGTAATTGTCACTATTAAAAACAATGGCATAGGAATGTCAGAAGAAGTTAAGAGAACAGTTTTTGATAAGCTTTCTAATACTAGAGCTTTAGCTAAAGGAACAAGTTTAAGTTTATCTATTGCTCATCAAATTGTGGTCAATAATTATCATGGTAAGCTTTGCTGTGAGTCAATTATAAATAAGGGGTCAAAATTTATTTTGCAATTACCAATAACAGAAATGAGTAAGAATATGAGATAATAATATAATATAAGGTAGACAAAAAGGAAAGTAAATAATCAAGTATAAATGCTGGAAAATTAAAATTCACAGCTAATTCTAATTTAGCTATCTATCAAATATTTTATATTTTTAGCAAACATTGATTAAGTTTGTATAAAAACTAAGACTTACCAAATATTGAATCTGGTTATTTTACTATAAATAAAGTATAGAAACTAGGGAAAGTATTAGATACTTGATCATATTGACATCCGTCCCCTATAAATTCGGTTTCTGATAAATACTTCAAAGTCAGTATATTTGATATAATATTACTCTGAAAAAAAAGAATGCAAAATTATAATTCATCTAAGATAGTTATTTCTATCCCAATCTCCTTTTTTTCAAGATTTACTTGCTCCTTTGCTCTGAGGGAGGTCTGTTGTATGCAAACTCCCTACTATTTGGTATAATAAAGTGTTATGGATTTTTATATTGTAGATGTATTTGCTGAAACTAAATATTCTGGTAATCAATTAGCTGTATTTACTGGCGCTGAAGTAGCTAATCTTTCTGATGAGAAAATGTTACAAATTGCTAGAGAAATGAATTATTCAGAAACTACTTTTCTTCTCTCTTCTGAACAACAAAATGGTGGTTACGATGTGCGAATATTTACCCCGACTAAAGAATTACCTTTTGCCGGGCATCCAACTTTAGGAACTGCTTATATTATTCAGCGAAAAATTATTAAAAGTCTGGTAGAACAAGTAGTTTTAAATCTGGGTGTAGGGCAAATTCCTGTGAGTTGGAAAGGTGAAGTTTTATGGATGAGCCAGAATGTTCCGACTTTTGCTCAAAAACATCAAGTTGAAACTGTGGCAGAGGTATTAAATTTAGAAGTAGTTGATATTGATACTAGATTTCCTATTCAGGAAGTTTCGACAGGGATACCTTTTATAATTGTACCTTTGAAAAGTCTGGTGGCATTGAAAAAAGCTAAGGTTAATTTGGATAAATATTATCAATTTATTCAAACAACAAAGGTAACAGAAATTTTGATATTTTGCCCAGAGACATACAAAGATATTGATGATTTAAGCGTGAGAATGTTTGCTCCCTATTTAGGAATTACTGAAGACCCGGCAACAGGTAGTGCTAATGGTTGTCTAGCAGGATATTTAGCTGAGTATAATTATTTTAATCAGAGGAAAATTGATATTAGAGTAGAACAAGGATATGAAATTAATCGACCATCTTTATTATTGTTACAGGCTGAGAAAAAAGCCGGCAAAATCGAAGTATTTGTGGGTGGAAATGTTGTGATGATTGCTCAAGGAAAATTTGTTGCTTGAAACAGGAAGCAATGAGACTGATTTTCAAAATGGATGTGATGATATTTATCAAGAAAAACAAATAAAAGAAAAGATAAAAAATAGAATGTAAATTAAATATTCAAAGCTCTATACTGCGGGGGGAAATTAAAAATCTATCACGATTAACAAAATTCTTTCTAGAGGTCATTACTAATATCAGTCTCATCAAATAATGCTACAAATAATAAAATAAATATTTTTACTACGAACAAAGATTTGTAAAAGCACTACAAAATCCCACTAAAACTGATAATTATAAAAATATCTATTTTGGGGCTATTATAATCATTTCTACTATGTTACCTATTTTTACTCATCTTTCTCTATATATTTATTTTGTGATTGGTTACTTAAGAAAAAAAGCAATACATTTATAGAGGTATAGGAAGATGAGGATATAAGAAGATTGAAAAACTCATAATTAGCATCTTTTATTATTCAAGCACCAGGAGACTAATGCTAGAAACAATTCCAGCTCAAAATGTAGACTTATGGAGTTAGTCGATAACTTTAATATTCAGTTAGTTGAAGATAATAATTTTCCCTCCGAGTCGCAAGAAAATTTTCCAGAAATAATAGACATAGAAAAAAACTTTTAGATAAAGTTAGAAGAGGATTTATTAACTTACTTAATTATCTACCACTTTAAGAATATGTAGTCAAAATGTAAGTTCTAGAACCGATTTTATTTATTGATGATTTTTATCTTACACCCTTCTATATTAAGTCATAAAATTAGATATAAATAGAGAGCGAAGATGATGGAATAATTATCAAAGTTAGAATTGAAATTCTAGTATTAAAAAAACAACTTTTGGTGATGGTAATTGAATAAAAAAATCTGCATCTTTTGTGGAAGTGAGACTAGATAAAATATTAGTATATATGCTGGGAAATTCTCACAAAAAAACTAGTTATGGTCTAATTACTACTGGCAAAAAAATCACTTTTATCAAGTTAGTTAAAGCTGAAAATCATAAGTATGGAATTTAAAGTTTATTTATAACTCGAAACCCTAGAGATTTGTATTGGGTTCTGCAAATTTTGAAGCATTTAAGTCAAATTGTTTTAAATAGCTAAATAGTAACTACTCAGCGGTCACCTACTAGCAATAAGTGAAAAGATATTCAAATTTATAGTAGTTTTCAGGTTGGGAACATAAAAAAAGAGAACCCTGTAGGGAAATTGCATAGAACCTCCCTACTTCTCTACTGTCTTACTCCCCTATTTCCTACATAAATTTACTGCCTTTTGGCCAACCATATAACTGTAATCTGTAGAAAAAGTTGGGAAACAAAGCGAATAGATACTTAAAAATCTTAAAGCCAAAAGGCTCATCATAAGTTCCCACCCATTCCTTACTATTTTCTATCCAATTAACTATTTTTTCGGCTACCTGATCCGCAGGTGGAGCAGAATTAACGCGATTTTCTCGAATCTTATAAGCTTTATCATTCAAACGATTTACAGGTGCCCAAGCAAACTTACCAGCAATTACGCCAGGGCGATATAACCGCAGGCGAATCATATTTTTACTAGAATGATAAACAATTGGTCCGACACCAGACCAAAAATAATGTAGGGCTATTTTACCAGAATGATAAACAGGTCCGAAACAAGAGGGACTCCCATCAGCAATTGAGCCAATGGCAATTACATCTAAACATCTGCTCCGAGCTAACTTTGCTGCTTCAGTACCAACAACAGCAGGCCAAGAATAATTAACCCTATTCATCGACTCCACTAACTCAACTACAGGGATGCCACCCTCTCCCACTTCCGTCTCAATTTGACCAGCATTCAAAATCACCACATCTGGGTCATACTCAAAGAGTTTTTTGGCATCCTCAATAGTTTCTTGGGGTGAAATACATAGCTCATCAAAAAAATTTCCCTCTAAATTAGGTTGACGAGTCACACCAACAACTTGCCACCCCCGTGACTTATATGCTTTACCCATCGCACTACCTAAAGTGCCAGAAATTCCAGTAATTACAACAGTCTTCATTTTATTTTTTTATAAACAACTAATATATATAGCTCAATAAGTTTAGGTTAGGTCTCAAAACGAAACTCAATCATAATACAATATGGTTCAGTTAAGGATTTTTTTTGGCACTCCTGTAATTTGAAAAGCTGATTTAACTGTTTCATAACTTATGAGTGGTCTGATCTGAACCGTATTAAATCATAGTAAGGTTGTGTTGAGTTTCACTAGTCGATAGAGATATCACGCCTCATATCCACCCACTGTACATGAGAGTTTCGCTCCTCATAGGGCTCCTAATAATAAAGATTGCCACCGAAAGGGTGCATATACTTTCTTTTACCCACCTTTATTTCCATCTAGGGTTTGCCAGATTTTCTTTTAATGGTAGTCTACTAAATTTAGCTTTTTAGGTATCGGCTTCTTGTTTATAGGGGGCAGAGCTTCCTCTTCGTACTAGGATAAAAGCTGTTTTTTCAAGTTCAATTTCTGCTTCCCGCCAACCTTTTTACTTCCCCAGCTACATTATCTAGTCGCGTCAATTTAGCACTAAAGTGACACATTATTTAAAATAGTGGGTGAAAACAGATTGTTAAATGCCTCTCACAGCATAAATTTTAACCTTTTAAAACATCCTATCAATTTTGCTGTCAAATTATAGCTTTTTGTAATATAGTATCCGCAACTCTCAGAGCATTTGCCGCAATAGTCAAAGCTGGACTAACACCCAAAGCATTAGGCATAAATCCACCATCCACAACAAAAACATTTTCATGCTCATGTAAACGACAATCTTTGTTAAGCACAGATGTATTAGGATCTGTACCAAACCTAGTTGTACCTACCTGGTGGGATGTATGAATATCATCTTTATCACCTGTTGCTCCAAAAGATAATATTGATCCTGCCAAGCGGAATACCTGTTTTAATTTGCTCTTATAGTATTGAGAACGGTAAACATCATAAGGATGAAATTTGTGAAATAGACGAATTTTGCCATCTTTACCTAATTCTATCCGATTTTCCTGTTGGGGTAAATCTTCCACAATGCCAGTTATTGCCAACATTCGCTTGAGCAGAAATTCGGCGATGGTTTTTGGTATTGGTATGGGGAAATTTTGTTGTAGGGAAAGAAGTCCTGGAATAGGAACTGTTTGAGCTAACCCCAATTTGTGAGTAAATTCTTTATTTCCCAGATACAGGTCTGTAAACCCTAATTGTTTAATGAATTTATCTGCCCCTCCTGTCTCTTGTTTGAATAAACCTGCCACTAAAGCACCACAATGATACATATAATTACGCCCTACTTGTCCGCTACGTCCTGTTAAGCCAGACTTCATCAAAATAATTGGACTACCTAAAGCTCCCGCAGAAAGAATATAAAGTTTAGCTGTCAGTTCTTGAACTTTGTTAGTTTTGCGACAACGGAGGCGAATACCTGTAACTTTTTGGTGACTGTTAGTAACTAAACGGTCTGCTTCTGTGAAAGTTTGAACTTGAAGGTGGTAATCAAGAGTGGCCTTATCAATAGTACGTACTACCGTAGAAGCACGAGCTTCATTTGGGCAGTAGAAACCAGGACATTTTGAACAACGCAGACAACTTTTGAAATCTATACCAAAGGGCAGATGAAATGGCATTAACCCGGCATCTTTTATACCTTTTTCCAATTGTTGGTTAATTGGCTCGAGTGGAGGAACTGTAGCTGGATAACCTTTGCTTGGTGTTCCTACATTGGGCATTTTATATGGCCGATCTCCAGCAACATGAAATAATGTTTCTGCTTGCTCGAAGTAGGGAGCCATATCATCGTAAGTAATGGGCCAATCCCACAGGTGACGGGGTAGCCATTGGTCATAGAATTTACCAGGGTGGAAGTCATAAGGACTTGGACGCATTAATACACCTCCATATAAAGATGTACCACCCCCTAATATTCCGGCAATATGAAGTTGGGCGTTACGTCCATTAACTTCAATTTGGCGATCGTCAAAAGCTTCTTTATTTATTAACATTCTTTGCTCATCTTGGAAAGCTTCAACATCACTAAATCTTGGACCACGTTCTACTATAAGAACCTGTTTACCAGCTTTTGCTAGAGTATGGGCGATCGTTCCTCCTCCTGCACCGCTGCCAATAATAATTGCATCAAAATCGTAACCCACTACTCTCTCCCAATATATTTTTTGATTTTTTGATAGGGTTTGTATGTGTAGTGATATTTAGAAGTCAACTCATTTCACTGTGAGAAGTCTAAATACAAAAATTACTACTTGTACACCACTACCGATAAATTAATGAGTTGATTGAGAAACTTTTCTAGTTCGGTTTTGCTACTGACTTTATTCTGCTAGAATTTAACTGTGAAAAATAGCAAAAATTAGTCTCTAAACAAAGGATAGGAACTAGAAAATATTAATAGATAAATATTCTCAAATCATCGACCAACTTCCCAACTTTTGACAATAAAATTAGGCCTTAAGCCTCCTACTGCAGTAGGAGGTATTGTTAATTATTAAGTATTAATTGTGAAGAAGATAACTAAAATGATTAGGTTGATGATGAAACTTTTTCTTTTTGATTTTCCTTGCCAAACAATTTTTCTAAACGGTCTTCCCAGTGTTTCTGATTAATATTTGCATCTTGAATATAGGGAGAAATTGCAATTATTTTCATCATTAATTCATTCAAAAATGAAAGAGGAAAACGCATTGGTCTCATGACATCTAAAAATAAAACAGCACGAACACCATCAGTTTCATTCCAAGCTTCATGAGGAAAAGAATCATCAAAAATCATACTCTTTCCTTCTTCCCAATGACGAGTTTCATTTCCGACGCGAATACGACATTTTTCTTTTGGTTCAGGTACTTTTAATGCTAATAAATAACGAATAACTCCTTTGTATGGACCTCGGTGTTCCGGAATATGTTTACCAGGCATTAAAATCGAAAAGAATGCAGTTTTCATTCCCGGAATTTTTTCAATTAAACGAGTTGTTTCTGGGCATCTTTGACAATTTTTTTCTGCTTTAATTCCATACCCATACATAAAATATGTTTTCCACAAATCGTCAGGGCTAGTATAATCAGCTTGGTCTGGAGAAATATCTTGAAAATTGGGTAAATCATCTCGATATTTGAGGAGTTCATCTAATTCCTTTCTAATCAATATCCAATTTGCATCTATCTCGTTCACCCACTCAAAGTGGTGAGGTTCCAAAAATGCTGTATTGCCAATTAAGGAATAACTAGGAATTAGCTTTTCATAATATCCAAGTAATTTGGCTCCAATTTTATATATTAATATTTTCCTAAATTTTGCCTTTATATTTTCTAAAGAAAGTTGAAGCATAGATTTTTTGTCACTATAATTTAACCTAATTGGACAGTTTTTAATCACTAGTTCCAAGATAATATAATATAAAATAAACTCTCTAGGATCTCCATTAATAATATCTAAAGTCTAATATGAGTAGCACTATTACACCTTCTCAAGAGAATATAAGTCAGTTGTCTGACGCTAAGACGACAACCTTTACTTCGGGTTCCCTAGTAGGAGATTTTTTTCAAGAAACTCTAGCATTAACCCGTCGGTTATTTATTCAACTGAAGCGACGACCTTCTACTTTAATTGCTGGAATTATTCAACCTCTGATGTGGTTAATTCTATTTGGGGCACTTTTCCAAAATGTACCTCAAGGCTTATTTGGTGAAAGTCAAAACTACGGACAGTTTCTCGGTGCTGGTATTATTGTCTTTACTGCTTTTGCTGGTGCCCTTAATGCAGGCTTACCAGTGATGTTTGACCGAGAGTTTGGTTTTCTCAACCGCCTATTGGTAGCGCCATTGACATCCCGCTTTTCTATTGTCTTAGCCTCAGCTACTTTTATCGTCACCCTGAGTTTACTTCAATCAGCTATTATCATTGGTGCAGGTGCATTTTTGGGTGCAGGATTACCTAATATATTGGGATTAGCTACGATCGCCCTGATTATTTTAATGTTAGTTTTGGGTGTGACTGGTTTAAGCTTGGGTCTGGCTTTTGCTTTACCAGGTCACATTGAACTTTTGGCCGTGATTTTTGTAACTAATTTACCTTTGTTATTTGCTAGCACTGCTCTGGCACCTCTATCTTTTATGCCGAGTTGGTTACAAGTAGTAGCTAGTTTAAATCCTTTGAGCTATGCGATCGAACCTATTCGTTATCTGTATCTACATCATAATTTCTCTTTTGGTAGTGTAGTTATGGAAGCGCCTTTTGGTGATATTTCCTTTGGGATAGCATTACTAGTGCTATTAGTTTTTGATATTGTGACTCTAGTCGCAATTCAACCTCTATTACGTCGTCGGTTTGCCTAGATGTGATATCCTCCAACCCTTAGCCTATAGGTAAAACAAAGACTGACCTATCTCACAAGTTCAGCATTCGGTACTATCATATTACTTGTCTAGTTCATAGACCTCTGACAGACTGGACCGGATCCAAAAACGGTATCCTTCATAGTATAGTGATGGTATATGTGAATTAATGATGCCTAGTAAGGGAGCAAAATGCTCCCATTGCCCAAGCCCAATATCAAAATAGTTATAATAGACCATCATTAGCATACACCACCACCCAAAAAACAAGTTTTTAAGCCTGCCATTTAAAAGTTCGGAAAAAAATCAACTTCAGTTTTAGGTAAAACAGTCGCCATTACTATCACGACATTCTTAAACTATCAAATTTAGTCAAAGTAATAATTTAACTTCTGACTTGTGAGAGCTGAATTTTGAATTAAACTATATATATTTTCTTGATCAAAAAATATTAAAAAAGTTGTATCCTAAATACATCTGATAAATTCCCTAAAAAACTAAAATACTACATTATGCCTGCCCAACTTTTCACTAAAATTCTTTTGAGTACCTTAACCACAGGAATAATCACGGTAGTCCTGCCTCAGGGTACTTTTGCTCAATCTTATAACAATAATACAGTTAATCCTTTAAAGGATTTACAAACAATAGATAACTCTGATCCTTTCACTGGTTCAGGTGGGATAGATATGTTCGATATTATTCATAACTCCAGACTGGGAAATAAGCAGAACATGAAGGAGTATATGCTCGAACAACGTGATAGTCTAAATGACGCAGCAACACAGTTCCGCAATAAACAAAAAGAACTTATAGAACAACCACAGAATACTACTGGTAACACTCTTACTCCTTCTACAAGTAGTATGGAAAATAATCCTTAAAATACTTGTTAGTATTAATAGACTGATGCGTATTCAATGTTGCCTTGTATCAAATCCGATAGCATGGTTTTTATTCAGTATTAAAGATAAAAGTCCATATTTAGGGGCGAATGGCTATTCCCTCTTACACACTGAAATATTCTCGTGGAGGCGGTGCTTTACATTTTATTAACGCACCCTACTCGATCTTTTGACTAGCTAATTAGACATCTCCAGAAAAGCTTCTTAAGCCCTTAACCCGCCATTTCCAAATCAGCATTTTTGGAGAGGTCTATTATGTATAATTAGAATTTGCTTTTCTTTGTCTTGTGAGGGTAGAAATTAGGAAGCATGCAATTAGCAATTACAGCGATTTTCAGATTGATAAACCACATCGTCACAACCAAAAAAAATCTTGTAGATACCTTCCTAGGATCCCTTACGGTGGTCTAATGAAATGAAAACTGCTGTAGGGAGCAGGTCGGCACAGATAAATGCCTTGGTCACCGCGGAGGTAGTGGTAAGAATTGTCTCCTGATTTTTCTGCCTAAGTCCTTGAGAAATCAGATCTATGCATGAGCTTAAGCTACCCAACTTCTGCTACTTTTTGTACTCGGCAAAATTTGGCTATGAGCATAATTTGTGCCCATCCTTTGAGAATTAATCAGCAAGCTCTAATTATGTCTAACTTTTTAACTTCTGTAGTTAGCACTTATTTTCTCATGAGGAAATCATCCTTACTAATAGATGGAATATTAGTTAGATTTATAAATTGACCACCAGTTCCAAATTCTGCTTCTATATCATTAGCATTGTAGAATAATTTGCCGTTGTTGCTATTGTAAACAATTACTGTTGCTGAGGTTTCGGCATTAGAATAGAGCAGCATCTTCCACAACATGAAATACCCTGTCATTAATTGCACTCTCACACCCCGCATCAATAAAAGCCTTTTATTCTCCCTTAGAAATAACCGTTATTTCTCCACCACTAGCAATAATATCTAAATCTCCTGTAGCAGCATCTTCCTTATTCTCTGAGATAGTCAAATTATATCTATGTTTCTCCTGCAGTCAGTCGAATAGCATCATTTTCCGGGGTACTGTTCGCTTCAATAATAGCTTTCCTTAGAGAAAGTAACACGATCACTATCATCCACTATATCATTAGTAGTATTCACCATAATATTTGCTAACACTCCGGCATAACTTGCCTTAACTTCTGGTGTAAATGCTAACGCCGACTTAAGTTGAGCAAATATTACCTCTAAATTCCAGTTACCACCTCTGCTAACATTTCCAGTCAGTGTTTACGAGGCAGCAATATTTGCTCGGTGTGAGTTGATGAAGTTATCGAACAAATTCTCTACCTTCTTTACCACTTGCTATCTCACAAGCATAAATCAATATTTTCCCATTAGCAGACAAATATTTACCCTTTTGCTGAATACCCTCAACATATAAATGAATATTAGAGTTGTTGGGAAATAAGGTAAAATAATTTCAGAAAAAATTTGCCATAAAAATGCTAAATATTGAACGAGCCTTAAAACAAGACAGATTACTCAGAGCATTAACACCCATTAAACCGTAAAGCATTTGAATCTTTGTTGGAGTCCTTTGGGCAAATGTATGAGCAAACATTGCACTCGCTCACCTCGTCAACGCTCTGTTGGAGGAGGTCTTTTGGCTCGTTTACGCACTCTACAAGACAAATTGTTTGACATTCTCTTCTACTTTAAATGTTACCCGACTTTTGACTTAGCTGGTATCTTGTTTGATATCGACCGTAGTCAAGCACATTATTGGGTTCATCGCTTACAAACTATGTTAGAAGCAGCCTTGGGAGAAAAAAAGGCGCGATGCATTGCGTCAAATTAACAGTGTCCAAGGATTCATAGAGCGTTTCCCTCGAGTAGAACGAGTGATAATGGATGGCACAGAACGGCCAGTACAAAGACCAACTCACTCTGAAAAACCAAAACTGAATTATTCAGGAAAAAAAAAGCGTCACACTCGCAAACATCTAGTAGCAGTTAATCAAAACAAGAAAGTGCTGGTATTGAGTCAGGCACGAGAAGGAAAGCTGCATGAAGTCGAAGTTCCATGACCAGGAAAAATTGATAGGAAATATACCTCTAGAGATTCCGATAGAAGTAGACAGTGGTTTCCAAGGTCTCCACGCATCAGTATGAAAATATCCGAATCCCCCATAAAAAACCAAAAGGGGGAGAGTTAAGTGAGCAACAAAAACAGATTTTCGGAAATTGAGTCAATCAAGGGTAGTCTGTGAAAACGCCTTGGCGGGCGTCAAGCGTTATGGAGCTGTCAGTCAGATTTCTCGTAATCACAAGTATGATTTTGATGACAAATTAATGCTAACAGCAACTGGTGAGTGGAACTTATATCTGATGACAGCATAAGTAGTCAAATTACTAGGGAAATATGTCAAGTTTTCGTTTGAGTTTTTTCTCTCCTAAGTTATTTCCCAACAACTCTATTATCTAAATTCAGGATACTGTTTCCCAGGTACATAGCACCTTTTGCACCATGAGAAATAATATGGACTGTATCCACATTATGCCCTTTACCCAGGCTTTTAGATATTTGGTTTATACCATTTTAATGGGGTTGTAGGACAATTATTTTTGTCTGAGGGTCAACCTCTGAGATTAGGTGATTGTAATTTTCTACCTTGGGGTCGATGAATAATAGTTTGTCTTGATTCATAATTTTAGAAGGGTGGTAAAGCTATCAGAAAAAAATTACCATTATCATAACAATAAAGTTTTTGTTTACAGAAACAATTCAAAATATCAGTCAATAGTCAATAATTTAAAGTCAAAAGTTAAAATCTAAGATGAATTGACAATTTATAACTGATAACTGATATATAAATACAGTTGTTAAATTTCTAGAAACCCCATGAATGTACAAACAGTTGTAACTAAACCATTTAGGGACCAAAAACCAGGCACTTCTGGACTCCGCAAAAAAGTACCAATTTTTAAAGAACCCCATTACCTAGAAAACTTTATTCAGTCTATCTTTGACAGTCTAGAAGGTTTTTCGGGTCAAACATTTGTACTTGGTGGTGATGGTCGCTATTACAACCGTCAGGCAATTCAAATAATTCTGAAAATGGCTGCCGCTAATGGAGTTGGTCGAATGTTAGTGGGTCAAGGTGGTATTCTTTCCACCCCTGCTGCTTCCTGCATCATCCGCAAAAATCAAGCCTTTGGTGGTATAATTTTGTCTGCTAGTCACAACCCTGGTGGACCAGAAGAGGACTTTGGTGTTAAGTACAATATTAGTAATGGTGGCCCCGCTCCAGAAAAAGTGACAAGTGCCATTTATGAACGTAGTAAAGTTATAGATAGCTACAAAATTCTTGAAGCTAAGAGTATTAACTTAGACCAACTAGGTAGTGAGAAGTTAGGGGAAATGACTGTAGAAGTTATTGACTCTGTAGCAGACTACGCTGATTTGATGGAATCATTGTTTGATTTTGGCAAATTATCACAACTGCTAAGTTCTGGTAAGTTTCGGATGTGTATGGACTCATTACATGCTGTTACCGGACCTTATGCTAAAAATATTTTTGAGCAACGCTTAGGGGCTCCTCTGGGTACAGTGAAAAATGGTATGCCTCTGGAAGATTTTGGCGGTGGACATCCCGACCCTAATTTAGTATATGCTCATGACTTGGTAGAAATTATGTTTGGTGATAATGCTCCGGACTTTGGTGCTGCTTCTGATGGGGATGGCGATCGCAACATGATATTAGGGAAAAATTTCTTTGTCACTCCTAGCGATAGTTTAGCAATATTAGCTGCTAATGCTAAGTTAGTTCCTGGATATAGTTCTGGTTTAACTGGTATTGCTCGTTCCATGCCAACTTCGGCAGCAGCAGACCGAGTAGCAGAGAAAATGGGTCTTGACTGTTATGAAACTCCTACTGGTTGGAAATTTTTTGGTAACTTATTAGATGCGGATAAAGCTACTCTTTGCGGTGAGGAAAGCTTTGGTACAGGGTCTAATCATGTACGGGAAAAAGACGGACTCTGGGCAGTATTATTTTGGTTGAATATTCTGGCAGCAAGGCAAGAGTCAGTAGAAGATATTGTTAAAGAACACTGGAAAACTTACGGTCGCAACTATTATTCTCGCCATGACTATGAAGGGATAGAAAGCGATAAAGCTAGTACTTTGATGGAAAATTTACGTTCTCTATTACCTTCTTTACCAGGAAAACAGTATGGTCAATATGAAGTCAAATATGCTGATGATTTTCGCTATACGGATCCAATAGATGGTAGCGTGAGTCAGAAACAAGGTATTCGTATTGGTTTCAGTGATGGTTCTCGTATGGTATTCCGACTTTCAGGTACAGGAACTCAGGGAGCAACTCTACGTTTGTATGTTGAAAGTTATGAACCAGATACTACTAAGCAAGACCAAGATACTCAAATTGCATTATCTCCTCTGATCAGTTTAGCAGATGAAATTGCTCAAATCAAGAATATTACAGGCCAGGAAAAGCCAACTGTAATTACCTAATTTATAAAGCAGGGAGTATTAGATTTGTCGGTCACTTAAAAAATCACCAAAAACCAAGTTCAGTAAAGATTGTAGCTATTGTGCATCAAGCAAAGCTTAAAAATATTGCTGTATCTAGCTTAGAGCGGTTTTTCCTTTCTACTTAGCTGCAACTCTATTATAATAAATTGCGTGTCAAGAAACTGGGTGTATGGAAAAAAGTATGTCAGTATGTTAGGGCATCTCGTGCTTTCCCCGGTTTCTATCCTTTTTAAGGGCTAGGGGGGATGGCTACCTCAACCTATCAGTACAAACCCTTTGATATCTTTAATAAAAACATCACAAAGTAGTGGATACGTGTCCACTACTTTGTGATGGGGTAGGTAATAATTTAACACTACCCTCACCAAAAGAGTGATGGAATGTATTGGGTCAATCATAAAAAAGAATAAAGGATAAAGAATAATGACACTGGAATACAGTTGGTGATCAAATATGAAATATGAGACAAGCACATAGAAGCGCCAAAAATTAGTTACTCAGGTTCTGCAAACAATCAACCCAAGGGTCATTGAAGATAATTCTTTGTCTTAGAAACTAGAGGTAATAATGAATCTGTATGAGCGCCTTCTAACACAACTCAAAGAATTATAAGAAAAAAAACAATCCCTAAAAGATGCTTTGTTGCACAAAGCAAGGAAAGATGGTAAAAATAACAGTGGGTAGCACAAAATCCTGCATTAACTCTCCTTATGAGTAAGTCTAAGTCTAAGTCCAAGTCTAAGTCCAAGTCCAAGTACCGGGTTAGCAACTGGTCGTATGGATGATGCCTCCTTAAAGCAGAGAGGGAGTCTGACATTTTGGCTAAGTTATGAAGTGATAGAACAGTGGGTAAATCAACATCAAACTGGGCGTCAGGGAGCATCGAATACCTATAGCGATGTAGCTATTGAACTAATGGTCACTCTCAGTAGTTTGTTTGCAGGGCGGGGCGACAGACAGAAGGATTTGTAGAATCTATATTTGATTTTTAGAGATTAGATTTACCTGTACCAGACCATAGCACTGTATGCCGTAGGGTCAGAAAACTAAATATCGGGATACCAGTGAGAACAAGGACAGAAGGGATGCATTTGGTAGTTGATTCTACAGGGGTCAAAGTCTACGGTGAAGGGGAATGGAAAACCAGGATTCATGGTGTAGGTAAACGTAGGACATGGCGTAAATTACTAGAGTGTGAATGAGGCCACCGGAGAGATTGTCACAGCAGTTGTCACAACCAATGATGTGAGTGACGACCAAGTATTTTCTGACCTATTAGATGGAGTAGAAGGTGAAATAGCCCAAGTTTCAGGTGATGGGGCTGATGACAAATACAAGTGCTATGAAACAGCTCACCAAAGAGGCATAAAAACGACCATTCCACCGCGTAAAAATGCTGTGATTAGGCAGCATGGCAACTGTAAAGCCCTACCCGCTCCCAGAGATGAGAACCTCAGAGGAATTCGTCAAATAGGACGGCAAAAATGGAAGCATGAAAGTGGATACCATAGACGCTCTCTATCTGAAACCACTATGTTTAGGTTCAAAGTTTTATTTGGTGGGAAGTTACGAAGACGATAATTTGATAATCAAGCAGTGGAGTTATTCATTCAATGCGCTATCCTGAACCCCATGATACAGAATGGTAAACCCGAAAGTTATCAAGTACACATCTAGAACTGCATCTCTCCAGGGAGTCATCTGCGATCGCAACATTCATACAACAAAGCTATTATTAAGGTTAATTTTGCCTAAACCCATTTGATAATTGGCAGGAATAGTTTTTGATCATCAGCTTTCTGACTGGCTAGTCCGAAAAAATCTCATAAGTGATGATGCGCCTTAGTTTAAGTTACTTTCAGTATTGAGTTGGCTTTGTGTTGAGTACATCAGGGATCACATTATCAAATGTTAACTCTCAAGGTTAATTATCATCAAAAACTCCTCCAACAATTCTGGGATGATTTTTGGTCTGATACAGAGATTTACTGGCCGGGAACAGATACTCCCATACTTTCGACTGCTTTAAGACTACCCTCTGAATTTTTAGAACTTTTCACAACTGTGAGTAGGTGATCAGCAGCTTGGTAGAACCAAAACGATTAACTGTTACCCTGCATTTGAGAGTTGCTGTTGGTGTTGGAACATCCTCAATTGCCATTCCATAATAACCAGGTGCAGTTAGCTGCTTGAGCTATGTTGACTAAAAGCTATATAAGTTATAGAACTCAGACGATGGAGCAAACTGAATCTTGGGATATTTTTATGTTCCTGGTTGCTACTACTCGTAAGCTAAGATTAAGGTTTTTTAAATAGACCTCTCCAAAATAGAAATTAAGGTAAAATTGTAGTGCCAAATTATATATATGCTGTCCCCAAATGAATAATGTATTAGAATATATTTATAATCATCCATCCATATACAAAAAGGATTATTGGTATTACAGATAAACAACTAATAAAATTAATAGAAAATGCTCAAAAAGTTGAAGACAAAAAAAGACAGGCGATCAAAGAAAGAAGAAAAAAAATTAATTAAGGCAGGAGGAGTCAGAAAAAAGTCTTTAGGCAAAGCGGAAGAGATAATTTTGACATTATATTATTTGCATCATGTACCAACATTTCAACTGCTAGGAGCAATATTTGGAGTTAGTGAATCAACAGCAAATAATATTTTTCAGGCTTTGGAGCGATATTTTGATGGAATTATTACCATCTAGTTTACTAGAGGAATTCTCGGGAAAAAAAACGAATATTTATGGATAAAAGAAGCTTTGACAGAAATAGAATTGATAGTTGATAGTACAGAACAGGATATATTCAGGCCAAAAAATGATGGAAAGCAGAAAAAATATTACTCAGGAAAGCAAAAAAGTCATAGGTTAAAAAATCAAATAATAATCACAGATAATGGAAAAAAAATAGTTGATGTAATAGTAGGAGAAAGAGGTCCAGAGAGTGATATAATTTTATTCAAAAAACAACAAAAAAAGTTTGATAAAGAACAAAGATTTCAAGGAGATAAAGGTTATCAAGGTGGGTCAAGAATTGACAGGCCAAAGAAAAAAAAATAAACCATAAAATGTCATACAAAGTAAAGAAAGAGAATCAAAAAAAAGCTCAAAAAATAATATTTGTAGAACATGTAATAAGACTGATAAAAATATTTAAAGTGGCACGAGAAAGATTCAGATTAAAAGAGAGTAATTATGAAAAAGTAATTTTAACAATATGTGGTTTAGTGAGATTAAGAGATTAAGCACTAATGTTAACATAAATCCTAACTTTAGGTCTAGTAAAAAGCAATAAATAATTACATAAAAATGCTAAATAATTAACAATAACTATCTGTAATACTATAAATATCATAAAAAATGACTATCTAGAGGAGCTGGCGATCGCTCTGGAGAAGATAGTGACAGTAAGGGAAGTGATAATTTTTGGAGATGTCTAATATGTACAAGATCGCATTTTTCAGACCATGAATATTCCTGCTGTGGCAACTATTATTTATGTTCGCGGAGGGTGGCGTTAGCCGTATCACTCCTTTATTCATTATAGATAGCGGGATAAGTCTATTTTTTAAAAATAGTTTGTTGGTTTATAATAGTTGACGTCATTAACACCTGTGAGATTTGAATCTATGCAATGTCCTGGCTGTGGCTGCCAGCATATCCGCAAAAATGGCCATCGACTAGGCAAGCAGAACTATATTTGTGTCCCTTGTAGCCGTCAGTTCATCGAACCTTCTCACCCACCAGGATACAGCGATGATGTCAAAAGGCTGTGCTTGAGAATGTACGTTAACGGTATGGGTATTAGAGGAATTGCGCGGGTGACAGGGATTACACATCCAACTATTATCAATTGAATCAAACACACCGGGGAACGCTTACCTGATGCCTTATACCCAGAGCAACTGCCTCAAGTAGGAGAACTTGATGAACTTGAAATTTTTGTTGGTTACTAAGAAAAACAAGGTATGGTTGTGGACTGCGCTAGACCATTTCCGTCCGAGAATTCTAGGTTTGGTAGTAGTAAACCACAGTGCTGATACTTTTCAACCGTTATGGCAGGCGATAGCCTTTTGGCAGTGTTACTTTTAGGTTACTGATGGCAATGGGGTCGCTTCCAGGCTTTATCCCTGACGGAGATCAGATCGTAAGTAAGACCCATAATACCCGCGTAGAAGGGGAAAACACCAGTTTACGCTACCCCAAGGCCCGCTTACATCGTAAAACTTTGTGTTACTCAAAATGTATTAAAATGCTCAAACATTCTATCCGTCTGTTGATTCACGCTTCTCAAATTTGGAGAGGTGCCTATTGCGGCTTAATTCATCCCTTAATTTACCAACGCCTTTTTCTGAAATCTATTGACGTTTTTTTCTGCTCCAATTAGACTGACTCCTTAAAAACAAGTCTAACTTTTTGAACACCTTCTATCATTTGTAAGCCAAATTGACCAGAGGTAAATTCATCTTCATCTGAGCTGCTTAGAGTCTCCTTCATTTGTGTAGCGAACTTTTGTAAATCAATCACTTCTTTTTCTTCATTCTTCCAAGGAATAGGAATAGAGTTTTCCATTAATTCTCCTTCACTATTTCGTAGATTTTTTGACCATTCTGGAGAATCTTCCGTTGGTGCATCTAACCCAAAGTGCATTGACTCCGGTTGTAAGTGAATATCAACGGTTTTGATTTCTCCTTCAAATAAACAAAGTAACACATCTTTAGCTAAGGTTTCCATTCGTAGTAGGGGTAAAAGATTGGCTTCTGTGGGGTCAATTGAATCTAAATCACTTACAACCTGATCATATCCATCAACCAGTAAACCAGGCCAACCAGAAACTACTTGCGATCGCATAATAATTCCACTAATTGTTTTATTTTGCTGACGCAGAAAATTGTTAAGTTCTATAATTTTTTTATCGTCTGATAAATCACCTTTCGTAACACGACCAACACTAAACGCACCATCCTGTAAGCAGTCTATCCAAACAGAATCTAAACAGAAGAAACGGATAGATTCTGGGGGTAATAAGCCCTCATCAGGTACTAAATAATTAAAAGGAACACCTTGTAATAATCCTAACCCTTGAAACCATTGTTTGACAGGGTTTGGGATAATTTTTTTTGTTTTGCTACTTGTGGAGTTAATTAGTCGTAAATGGGTCTGTTGTTGTTGCAAACGTTTGATATTCTGTACAACTTCTCGTTTCCATTTGAATAGTTGAACCGCTAACCCTTGATTTTCTAACATTAACATTCGACCTAATTGCCAAGCAGCAGAATAGGAAATATCAAACATTCCAATTTCGGAATCATAGCGTAATAGTTGATCCGATGCTTTCATAGGAAACTCATAGATTTCTTGTTCTTTATCATTAAAAGCTGTACCTAGGGGACTGCTATACCAAGAATAGGTTTTACTTCCTTTTCGGAGGGAATGGGGAATAGTAACGTATCCTTTTTTTAAGTATTCTTCTGCTTTTTCATTATCACTTTTGGGAAGTCTTGGCGAGGAAGGAGCATGATTTAATCTTTGCAATAATTTGGTGAAACTTTGCTCAGGATCAATACAAGAAAATTCCCAACTCGCTAAACTAACAAAGCGAATTAAATCGTCTTCTTTTGCATCCATAAAATAAAATTTATTATTAGAATAACGCCCTTCTATTGACACTAAATAAACCGTACTTTTGCCACTGGGTTCGGGGAGACGATTACAAATAATTGTAGAATATTCTTTCTCAAGTAGCTTTAGATTTTCTTCTGATGCTGATGCTAGTAATCTTCGACGAACATGAGCAGTATAAGAAAGATCCTCGTAAGTTGGTAAAATGTCTTGAAGATATTTCTTTTTAACATCAATAACAGTCACTTGTTGGTTTGGCGTTTGTCCTAATTCTAATACCATTGTAGGATATTTAATATTAGGAGAGTTTTCTGTAATTAATTCCGAAAGGGTAACATTTTTGGGTTTGGGTTTATCCTCTTCATTCCCGTCAAAATCGCTTTCTCGGAATAATAATAAAATTAACCAAGGCAAGTTGTCATCTGTTTGTCCAGGGTAACGTTCCCAAGGCAAGGTACTTCTTTTAAAAGTAATATGGGGTAAAACGTTGGAATGTTCTCCTAAACTTTCAGGGGGAGGAAAAACGGCATAAATATCATTAGGAGATAAGGGACCAAATCGTTCACCTTGGACAACAAAAGTTAGTTCACGACTATAGGTTTTACCATTACCATTGTTATCAATTTTATCCCCTGCTTTGATGGTTTGTTCGACTTTTAAGTCATAAGTTCCACTTTCTAATGCAGGCTGATGGAATTGGATAAATTGAACTTTTCCTTTTTCAGTTGTTGGCATGGGAATGACTCCTTTTTGTTAGTTTATAATTGAGTTGGTTGGGTTAGCAGTAACGTAACCAAACAAAAGGTTAATGGATGTTGGGTTTCACTTTGTTCAACCCAACCTAGTGTACAATTATGTTAATTATTTTACTTCAGTAGTTAGCCCACAAAAAATTATGTTTTGATGATGTAATTAAGTGCATAATAAGGTGGTCGGTTTTCGAAAGGTTTATTGTTTCCTATTACCTGAAGAGCTTCACAAGAGCCAAGATTTGGCTCTCTGAGACTGTTATTAACATTGTTTGAGGTAGTCACTTTTCCATCCTTTTTTAAAATGAATTTATATTCACCCTTACTATGATCATGGCTTGGCATTTCGTCTTTTGTTAACGTGTGCTTTTCTTCTCCGCCTTTGGCATTAAGACTGTAGGAGTAGCCATCTTTATCTCCAACACCGATGATAAATCTTCCTTTTAAATCTGGAAGAACCTTTATTTCATCAAGCACCTTGTATAATTCTGAATACTGCTCCCAGTCGTATGACTGACCATTGCATAACAACCAACCTTCAGGGGCTGTTAAACCTGCATAAGGAACAATTGTCCCTACAGGAACGACCCAGCCAGTGCTATCTTTAATTCGTCCACACCCAACTTCTAGGTTACCTTCCTGATCAAGCAGCATCTGTGTGCGACCCCCATCACCAGGGGTTGTACTTGTTTCTTCATGACTACCTCCTAGATACCAAGCAAAGTATCCGTTTGTTCGGAAATAAGTGGTATTGCCTTGTGTTCCAACTCCATACTCTGGACCCCATAAGTTAATTCTTTGTCCAGTCTGACCACTTTTGGCAGGAAATTGCAAATCACCGCGCGATGTTAATTCCATCAAGGGTAAGTCATTTTTCTGTTTATAAAATTTGACAGATATATCATCATTTGATGTATCGGTATCAGACCGAAAAATCAAAGTGCCCGTGTGGTTAATTTCCCCTGGAGCATCTAGACTAATCCCATCTTTCACGGTGAGAAGTCCATCTAATGATTTGTTGGTTCCTATGCGGACTTTCTCATCAAAAACTAAGGGAGCTTTTTCAATTTGACAAACAAATTGTCCGTCTCGGTAACCATCAATATATTGATAGCGTAAATACAGGTTAGTCTCTCCTGTGGGGTGCGCTGTAGTAATACCATCCAAGTTAATTAACAAGGTTTCTTGCGAGTTTAAGACCACATCAGATTCTTGAGGAATAAACGTCCATTCCAAAGCCTTAGTTTGACCGTTAACCTGAATTTCTTCCGGACCATCACTAAGTTGCTGCCAATTATTAATAGTAATATTAACACCATTGACATCATCTTGAGTACCTAATGCCCAAGGAACCGAATCTTTATCTCCTACTTCTAAAACAATCACTAACTGAGAACATTGATCCGAGTTTGCATTATAATTAAAGGTAATTGCTGAGTTATCTGCATTTGAAAGATTTGTGTTAGTAATTCGCAGTTGCAGACGGCTATTGTTATCGTGGGTATTGAAAACTTTATTAGAACCCACAAAACCGACATAGAGAGGGATGTTAGATTTTCCAGATGTTTTTTTCATTTCTAATGTTAGGGTAGTTGTTGTATCATACGAATCATCTTGTCCAGGGAATTTAACTTCCGCTATGCTAATGTTTTTCTCTCCAATTATCCAGTTAATGTTGACATCAGCGACTGCTCTGGCGCTAGCACTGTTATTAGCCAAATCAATAACCTCTGTTAAGATAGCCTCTGTAGCACTGTTATTAGCCAAACCAGCAACCCCTGTTAAGATAACCTCTGTTTCTTGACCAGGGTTGAGGATTATTGGTGCTTCTGTCCACAATAAATACAAACACACATAGTTAGGATCTGTTTTGATATAAAGTGACCAACTTTCGGTTTCTTCAATCTTAATTTGGTCGGGATCAGCTAAAATTCCTGGCTGAAACGTTAATTTAAAATGATAATGTTCAGCACTAGCTATCGTTACCTCTGGAATGGAAGCAATTGTGATAACCTTATCAGAAAGAGTATTTCTGAGACCAATATGGAGTGGGGTAACTGTCTCAGGTGTTCCTAACAGTAAACATTGGCAATATTCTTCCTCATCTTCGTCTTCTGGCTCATAACACCAGAAAAACTCAAACGGCATTATGGGTGACATAAACTTAGTTCCTTCATATTAGTTATAAGTTGTATAGTATGCTTGATGACACTATATTGTTATTCTTTGATTAAGTCAATAGAGCTGTCGCTAAACAGAGGGAAAAATCGCTCTAACTTAGACGGAGCAAAAGTTTTATTTTTCTTGTTTTCCAATAGCTACAATCTTTGCTGAACTTGGTTTTAGGTGATTTTTTAAGTGATAAAGCGACAAGTCTAATGCTCCCCTTATACTAAACTTAACCCAAACTTACATGGATCAGGAATTACATAGGCTTTGGAGCTAGCTTCAGTGTTTCACGAATATAGCACTGACCGCAGTCTATAGCTTACCTATTCTATAATCTAGGCTTTAAATTGCTCTTAACTTAAGCCAAATAAAATACATAGTACTCTAAGTTGACAGCAGCATTAGAATCTTTAGGTTAATTTAATGAGGGGGGCAAAGACGAAACTATTAGCGATCGCCTCAGCCTCATCCTCATTCATATCCACTTGATAAACATCCCAGCCCAAAGCGGCTAAAATCTTGTTACGTTGTTCATTACTGCCTACTGTTTGCATAATTTTATTTCGTTTATTTTCTTCATCTAAGTTGGGATTAGGCACAAAGGGGGTACAAGACTCCCAAAGATAAGCATCCTCAACCTTTTCAGTCTCATACTGTAAATGTTCAACTCCAATTTCATGAGTTTTACCTGCTTTAGGGAGTTCTGCTGGTAGAATGCGGAAACCAAAGAACACATTCTCTATAAATTGCTTCCCATTGACTTCAGGGGGTTTAATATGACCATTCACCATATTAGGTTCTCCCCAAGTAGAAGTGGATGCAAGTTTAGTGATAGGTTCAAACTTAAACTTGTCTTCTGCTCTTTCTCTGGAGTCTTTACAAATTGTCACCTTATGGGTAGTGTCCAATTCATTATTATCCACTCCCATTGAATTAATACCAAAATTAGTATCTGTATTAATTTCTTTCTTCTGTTCTCCAACAAACGCTTGTTTTGTAGGAACTAAGCTATCAGTACTCATTTCAAAAACAGTGGGATTAATAATCCAAACTTCCTTTTGTTCTTCTTTTCTTGTTGGTTCAAGAACTTGTTTGACTAACCCATTAATAGAGGTGAGACTACAAACATTTTCGGGTTCAGGTAAAAAGGTGTCCTCAAACTCATCCCATTTAATGGGCACTGGATAAATGGAACTTTGATCCCCAATTTTAATAGTAACTTTGCACACAAAAACACGAAGCTCTAATTTACCGCCAAAGTCAGGGCCCCAGATATGAACCCCCATACCTAAACCTACCGAAAGTGCACCAACACCTACCCTGACAGAGCAGTAAACATTCACATCATAATGATAGGGTGCCCAACCGAGGAGTAAATCAAGTCCTGCCTCAAAATGGGCCCAAACTGACCCCAGTTGATAGCGAATGTCCATCAGTCCTCCGGCCATGATCCCGTGACCACAGATAGCAAAATAAGCCTGAGCAGTAATATGGGAATGACTGTCAATTTGCCAATTCAAGCCCAGTCGAGGCACATTAGGGTAATAATCAGGCACTTGAAAGCGAGGATGATAACCCCCTTGAGTAAATACAAAATCACCCAAAAACCATAACCCGTAAGCAAAGCCACCCGTTAACCGACAATTGCGACTAAAGATGTAGGAATTTTCCGTCAGTTGTCCTTGAATTAGAATCACCCCTTCCATTGGGTTGAAGCGGCCAGCGATCGCTAATTCCGCCATAGCGATCGGTTCATAATTGTCTTTTAGTTTAGTGGGTAACATCATTGTGGCAATACCCAGTAAGTTAATTTCAAACTCATTCTGACTTATTCCCAGAGTAATTAACCCAAACCCATCGACAATTTTACAGCCAGTAAATTTCAGTCCGAGCGCCCCAAACCCAGAGCCAATAGAGGGGGGAATATATTTATTTAAGGCCTCCAATTTTTCAGTAATAATTTCTCCTGTTTGATCAGGATCAATTTTTTGAGGTCCTTTTAGAGCTTCAGTAACTAGGGGAAACTTTTTAATATCTTCAAGGGGCGGAATAATTAAGTCATGGTTATAGCCAAACCCACCAGAGATTCCGGTAACAAAGAAGAATGGGGGACCACCGAAGGGATAATCTGCTGCTAAATAGAGAAATAGGGCAAATTGGTCACTATTCTGATAATCAGTAAAAGAACCAATAGCAGAAAGGGCTAAGGCAGGGCCAACTTTCTTTTGAAAACTTACAGTGACTATTCCTAAATATTCATCATAGTTGTTCTGCCCTTCTGCTCCATGTGCTACTAGGAAAGCACCCCCCATTTCCAAACTGCGGGTTTTTAATTCCAAACCAAAGCCATCAAGATTAAAGTGAGGCTTAAAAGCAGTTAAACCACTACTAATATACAGTCCATTTAGTGCCAGAGTAAAGCGAGAGACCTCAATAATAAATTTCGGGGTCAGACGCATTTCGCCTTTTGTGTAAACTAGTCCTACTTTATCGAAGTAAAGCGGTCCAAAAGATTTTTGAATATTTAACCAAACCCCATTATCTGCTAGGGTAATTACTCCATCTGAGCTGACGTTACCACTGTCATTATTTGTTGTTGTGGTCAAACTACGACTACCCCCTGCAGCAGTGGGAGGCGTTTTAACTAAAGGTAATAACCAAGCTTGAACAAACTGAGCAATTTTTTTATAAACCAGTCCTACCTTTTGGAAGTAAAGCCGTCTAAAGAGTTTTTGAGTATTTAACCAAGCTCCATTATCTGTAGGGGTAATTACTTCATCTGAACTGACCTTACCACTGACATTATTTGTTGTTGTGCTCAAACTACGACTACCCCCTGCAGCAGTGGGAGGCGTTTTAACTAAAGGTAATAACCAAGCTTGAACAAACTGAGCAATTTTGAAGTGTGCGCCAATACTTGCCCCTCTTTCTAGATTGTTAATAGAACTACAAGGGGGTTTAATTAGTAACTTGGTACCCAGTTCTTCTAGTAAGCTATTAATGGTTTTAACTTCTTTTTGTGTAAATTTTTGGAAGGAAACTAAAAATTCAAAAGCAAATTCACCTTCTAGGGAATTAGGGGGAAGTAAAGACCCGGCTAATGGAATATCACTCAAGGCAATTTCTGCATCAAAGCCAATGCTAAATAGCATTTTATTTTGATTTCTTTGACCATTATTTGTGCTATTAATAACAAAAATAACATCCGAACCCAAAGAAAAATTCAACAATTCATCAGGAAATAGATCAGTTAATGATGGACAAATTTCACTAACTAAATTTGATAAATTAACATTACCCAGATTTTGGTTAGCATTAGCATCTAATGAACCTACCACTAATTTAGTATTTTTACCGGATTCAGTTTTAGTTTGATAATCTAAACGAAAGACAAGAGCTCCTGTTGGTTTTATTGGAATTGATAAAGATCCCCCATATACACCTTTGTAATTATTTCCATTATCATCAGTTTTGATCTCAATTACCAGGCTACCACTGAGTTCTTTAGTGGTTAAGCCCTGGCCCTCATCTTGTTCAATGGCAATGGTAACACCTAACGTAAAAGTAAAATTGTTCTGATCTTGGGTGCAGCTTGCTTGCCTAAGAGTAAAGATATCAATGGTATTTAAACTAACATCATCAAATAAAAACTCTGTCTGAATTAAATTAATAAAAGCTTGAATGTCATTTAGTCCTGCTACAATTTCAGCATCAATATTAGGAGATTTTTGCATAATTTTAGTTCCCCAAAAAGCATGTTTTGATTGTTCATTTGTATCACATTATTAGCCTGTCTGATTCATCTCACACCATTTGGTGTGAGGCTCAATAGCGACTTCAGCTAAATAGAATAGAAAGGTAGCCCAGAGGGCTAGCCCACAAGTGAGTTATTCATCTGTGATGTTGGCTCGACTAAGTTGCAACCATCCTTCCAAGGCTTCTTGCATTTGAGTAAATGTTGCTCTGGTGTTAATAGGTTTAATAGTTGCTCTTTCCGTCCATTCTTCCCCGTTCTCTGACTTAGTTAACGATACCCAAGACCAAGTTGCATTAGCTTCTGGAGATAAAGGCATGGCTAGTTCCCCAGAATTAGACAAAATGGGAGTAGAAAGGAAGTTCACCTCCATTTTCTCTAAGGCTTGGTTATAATGCTCGGAGGGTAAACGCAATTCTTGATTAGGTAAAACACCACAAGAAGCATGAACTAAGCCCCTGGGGTCAATTAACATTGTTACGCTTTGGGGTTCAGCATCCACGTTTTGCAGAAAGTGAACGATTCCCTCACTATCGGTAATAATGTTGTTACTATCTACTAAATTGCTTTGAGTGGCATAGAAGATATTGTTTTCATATTCATAATCGCCCTCTATCCCGTTGGCCTTGGGTATTTCTTTCCAATAACCCACCAGTCCATCATTGAGTTGTTGATAATCCCCTAAGCGAATGGGAACTTGTACTCCTGTAAAACCATAAGAAGGAAATTCATTTTCTTCCTGAACCAGAACCGTCGGATCACAAGCGGGTAAACCTTTTACCTCTAAACTAAAAGTGGCTCTAACAATAGCCATCGGTCGTCCGACTAATAAGGCTAAACCGGTATTTTGAGCGAAACTTTCGGGGTCAATGGTTTCTAAGGCATTATCCACAGTAGAAAGAAACTGCTGTTGAAAATCTTTCCCTTGTTCTAAAAGATGGTGAGCCAACTTCTGTAGATGATCATTTCCTAACAGAGGATAACCATTATGATCACGAGATAGTTTTACTCCTGGGGCATTACGCCAATTTCCCAGTAAATCAATGGAGCCCAAACTGCGACCTTGATTATCATAGATAGCTAGGTTACTATCCAAATTATTAGGAACAATCCAACCACAAACAGGTGTCCTGGCAGGGATTTTAGTATATTCAACTTCCTGTAAGGCATCTGCTGATAACCAATGGAAGTTAAGACGGGAGGATTGAGCAATACGGGGAGGTAAAATGGCTTGATAATTCACAGAATTTTTATCGGCTGGGGTCATTTGATAAGTTGTGACAATTTTAGTATTCTGATTGGAATCATTAACGACTTCTTGGTATTGTCCGAAGGTATCAATTAACCACAACTTCTTAACTGAAAATCCACCACTACGAATCGGGTTAAAAATATCACCTGAGAGAATTTTGTGTTGTAGCCTATTCCCTAAACTCCAACGCACTTGTTCTGTAACTAGTTGGCCAATATTATCAGTATCAAGGGGATCATCTACTTGTAGTTGTAGTGTCGGTTGTCCTAATAAAAGAGTATCATTGAAACCACCAAGCATTTGTGCCTGACAATCTAGTGTTTTCATCTTTCTATAAGCCCACAAAGCTATAAAAGTAGGATCGGCTGCCTGTTGTTCTTGTATCTCTAATTGATTTTCCTCTTGATACCAGTTGGTAATTTCATCTAAATTATCATCCAAATAGTTTGAGGTTTGATCTTTTTCAGAAATATTATTTTTGGAGTAGTAATTAGGCAGTAATTGTTCATTGAGGTAAGTGCTCAGTCTTAGGATTAACTCTGTTCCCGCCGATGGGGTTAAAATACTAAACCCACTGTACGTATTACCATTGGAGATAAAGCTGCTTTCTTTTCCATCTCTAAGTTTCAAATCAATGGCATTTTTTTGCAACTCATAGTTATCCAAAATCTGATTAGAGTTATAGTCTTGAACTGTTGAAGACTCTATATCACGACAAGGATAGTTCAGAACGGACCAATGGAAAGCAAAAGGATTCCAAGGTTGTTGAGTCCAAGTGATGAAATTAATCGATTCTTTGCTCTCATCAGGTTGTAAGCTATTTATTTGATTCAGTAGATCCTGATGATTATTGAGAATTTCTGTAATATCAAAATCTAAAGGAATACATTCCAATAAATCGTCATCGTGTAACCGTCCATCTTGTCCAAACCGTAGGGGTGATTTTGTCGATTCCCCTGCTAATAAAATAACAGGATCATTGCCTCGCCAGTAACTTTGAGTTGGAAAGGTCCGAAGTTGATATTGAGTGGCTGAATTTTCGTTATAAGTTGTTATGGCTTGGGATAACTCATTAAGTTTCTTGACCAGATTAAAGGCAACTTGAGCCTCACTCGGTGGAATATAAATAGTAAAAATACCGCCTTCGACTTTGACAGGATAGGTTAGTCCATTATCTTGTATTTCCCATTCTTGATCATCAATAATCTTGGAGACAATTGGGCTATCCGATATTTCTACCCCACAGTTCTTAAATTCAACTTGTATGTCTTCCCATTTGTTAAAAGAGCTGTTAGTGGCTAGTTGCATAGTATCCACATAATTACTGAAATAAGTATTTAACCAAGATAGAATGCCAAACGGTAAGGTTTTACTAGTAACTGTAGTGTTTCCTTTCTCGTCTTGAGTAAATTCTAATTCTCCCGTTTTAGCGATCGCTGTTCGTAAGGGAATTAGACTTGTTTTATTGAATATCTGGTAAAAATTGGTAGGACTTGTTTTATGTGTAATAGAGTAATACCACTGAGTATACAAGCGATCGCGCAATGAACCAATATCTAACCAAGCCTGATTATAGTCTTCTTGGAGCGCGTTCAATTCATTTAATAACTGAGCAAGATGATCGGGAAGTAAATCTAAACTAGTTTTTGTGTTGGGTTGTTCGAGTTGGGAAGATCGAGGCATCAATAACCACAAAACACCCTCATTTTGTGCCCCAAATCCTCTTTCCTGTCGACCTTCTCGGAATTTAGCATCAAGATCCAGTTTTCGAGATTCCAAGCGCTCTGATAAATGTAACGTTTCTAAGGTATCCTGAATACTTTTACGGACAGTTTTTCCCGAGTCATTAGTATCCCCATTAAATTCCTGGGCTAAATAAGCAGAAATAGCTTCTGAGTCTGAATTGCCAATGGCAAGAGTGGGTGTTTCCAAAGTTGGCCAATTCCCTGCCCCGGTAAAAGTTATGCGAGAATGATAAAGAGTGCGATGTAGTATATCTTTTACACCTTCAAAAGTCCAATAAAACTGCTCTTGTAGAGCTTGTAAGAATTCTTCAGCTGTTGTACAACTATTAGCTTCGACAAACTGTTTTAAACAGTCGTCTTCTGCATCACTATACCAACCAATTACATCATATTGTAAGTCTTTAGGAGGTGTATCAGTTTCAAAATCAGGATCATGAAACCCAAAAACACTATAACAGTTAGGATAAAAGGCTGCAAAGGTAGCTTTAACTTCATCAAAAATAGGGATGGTTGCCTGGTTGCCCATAGCGGTTAATTCTTCAGCATATTCTGGGTTTTCACCACCTTCTTCTGGCCACTGACTTAATTCCCAACATTTCCCCATATAACGATACCGTTGGTATTGATAAGTATCAGGCTTTTTGGGATCAACGGTTGCTAGATCAGGGGGTTGAATGAGAATATTAATGGCATTTGGTGGACTACTACTACTATCATTCGGATCTAACTCAGGGTATAAATAGTCACTTTCAATAACCCAAGTTTTCTCTTCTGTTTCTCCCCCTTTACGTACAATTAACCAACGGTTGGGAACTACTGGAAAAGTTGTTCCATTACTGTCGTGCTGTCCATTTGTTAGAGCATCAGGTAAAGACCAATGGAGATGGATTCCTTTTTTCAGGGTAAATTCGTGGTTAAATAATGGGCCTAAAGCTGTTTTACTTAAATTTTCGCTTCCTGAGTTGTAAGTATGCTCCTTATATTTATAAGGCAATAACGTATAGTCAACCATAGCTCTGACAGCTTGTTTATCCTCTTTTAAACATAGAGCATCAGTATGGATAGGAACTAGTAAGGTTTTACTCATAACTTTTTTAGGTTTTATTTATAGTTTACTTATTAACATTGAGTGTGATGGACCAGAGAACATTGAAAAAAGACTGAAATAATTAGTGCCAAATTTTAATTTGATCTCAGGTACGGTTGCCTGATTTTTAATAGCGGTTAATTCCTCAGGATATTCCTTATTTCCGCCTTCAAGCCACTGCCATAAATTTCCAACATTTCCCCAACAAGACCGTTGGTGATAAGTATTGGGATTATTGGAATCAATGGTTGCCAGTAATAGAAATTACATGAGAATATAAATGGCATTTAGTAGAACACTATTATTCCTCGACTCTAAGTCAGAATATAAATAGAGTTGTTGGGAAATAAGGTAAAATAATTTCAGAAAAAATTTGCCATAAAAATGCTAAATATTGAACGAGCCTTAAAACAAGACAGATTACTCAGAGCATTAACACCCATTAAACCGTAAAGCATTTGAATCTTTGTTGGAGTCCTTTGGGCAAATGTATGAGCAAACATTGCACTCGCTCACCTCGTCAACGCTCTGTTGGAGGAGGTCTTTTGGCTCGTTTACGCACTCTACAAGACAAATTGTTTGACATTCTCTTCTACTTTAAATGTTACCCGACTTTTGACTTAGCTGGTATCTTGTTTGATATCGACCGTAGTCAAGCACATTATTGGGTTCATCGCTTACAAACTATGTTAGAAGCAGCCTTGGGAGAAAAAAAGGCGCGATGCATTGCGTCAAATTAACAGTGTCCAAGGATTCATAGAGCGTTTCCCTCGAGTAGAACGAGTGATAATGGATGGCACAGAACGGCCAGTACAAAGACCAACTCACTCTGAAAAACCAAAACTGAATTATTCAGGAAAAAAAAAGCGTCACACTCGCAAACATCTAGTAGCAGTTAATCAAAACAAGAAAGTGCTGGTATTGAGTCAGGCACGAGAAGGAAAGCTGCATGAAGTCGAAGTTCCATGACCAGGAAAAATTGATAGGAAATATACCTCTAGAGATTCCGATAGAAGTAGACAGTGGTTTCCAAGGTCTCCACGCATCAGTATGAAAATATCCGAATCCCCCATAAAAAACCAAAAGGGGGAGAGTTAAGTGAGCAACAAAAACAGATTTTCGGAAATTGAGTCAATCAAGGGTAGTCTGTGAAAACGCCTTCGCGGGCGTCAAGCGTTATGGAGCTGTCAGTCAGATTTATCGTAATCACAAGTATGATTTTGATGACAAATTAATGCTAACAGCAACTGGTGAGTGGAACTTATATCTGATGACAGCATAAGTAGTCAAATTACTAGGGAAATATGTCAAGTTTTCGTTTGAGTTTTTTCTCTCCTAAGTTATTTCCCAACAACTCTAATAATTATTTGATAGAATCAATGGGAGGATTTCTCTTGCTCACCTCTCCTTCAAAAGCCATACATCATAGTTTTGCTCCTCATCAGGCTCCTAATTTGAGATATACATCTAAGAATTCGTCATTTATAATAGTAGATTATTCCCTTCCGATAGTTTAGTTGAACAATATCACAAGGGTTAGGATTCGCCATTAATAACACTAGATGTCCTCCTTCCGGATAGCTGAGTTTTGAAGCTTATTAAAAATGTTACTTTTTTTTATGACAACTACACAATAAATCTATTTAAACTTGCTCTCAAGATTTCATTATTTTTTTTTAAACATTTTTTTTTCAACTAGCATATGTTAATTGACAGTGACAATAAAAATTGGTTAAAGGCCATTTAAAAAACTAGATCAAGGTATTTGACTTGAACTTTTAGGTCAATAGTTCAAAGACTTATATTATATCATGTCCTGATAATTAGTTATAAAAAACTTCCTCCTCTTCTCACCTGACTTCTGTAGAGGCGTTTCATGTCACGCAGCGAAACGGCCTCCCCTACTTCTCTTTAGTTATTTATACTTATGCAACCTGACATGATATTAAATCCGGAAATGCTATCCTCTTTGTTGAGAGTAAAAATAACTTAACCTTGACAAGGAGTTAAAATTATGGTTACAACACCATCATTCAAGCCAACTTACGAACAAAACACTTTTAAATTATCACCTACAGCAACAACAACAACGTTGCCTTGGAATAATACCTCACTGCCCACAACACCCCTATTTGGGACAGATGGCATTCGGGGCAAAGCAGGAGAATTACTCACCGCCCCTATGGCCCTACAAATAGGTTTTTGGGCAGGACAAGTATTGCCCCAATATTGTCAAAATCCTGGCCCGATAATTATGGGTCAAGATACTAGAAACTCAGGTAATATGCTGGCAATGGCTCTCTCAGCAGGTTTGACAGCAGCAGGGTTAGAAGTTTGGAATTTAGGTTTATGCCCTACCCCTTGTGTTGCCTATATCACAAGTATTTCAGAAGCAATAGGCGGAGTAATGATTTCCGCTAGTCATAACCCACCCGAAGATAATGGAATAAAATTTTTTGGTTCCGATGGTACAAAACTCTCTTCAGAATTACAGCAAAAGATAGAATCTGGAATTCGAGGTACCGCAAATTTTCCTACCAATCATAGTAACTGGGGACAGCATTACCATAGACCAGAATTAGTCAAGGAGTACCAAGCATCTCTACATTCTCCATTAACACCAGGATCTCTCCAGGGAATGAAAATAGTTCTAGACTTAGCTTGGGGAGCAGCAGTTCATACTGCCCCAGAAGTTTTTCGAGGAATGGGGGCAGAAATTATTTGTTTGCATGACCAACCCAATGGCGATCGGATCAACGTTAACTGTGGTTCTACCCATCTGTCTCACCTCCAACAAGCAGTAATAGAACATAATGCTAATCTAGGGTTTGCCTTTGATGGAGACGCAGACCGAGTATTAGCAATAGATTCTCAAGGTCGTTCTATTGATGGAGATTATATACTCTATTTCTGGGGTCAAAGCTTAAGTAAAGCAAGGTTACTACCAAACAATTTGATTGTAACTACAGTTATGGCAAACTTAGGTTTTGAACACGCTTGGAACAAACAGGGTGGAAAAATATTACGGACAAAAGTAGGAGACCAATATGTTCATGCTGAAATGCAGCGCACCGGATCTATGCTAGGCGGAGAACAATCAGGACATGTTCTTTGTCCCCACTATGGCATTACAGGAGATGGTCTAATGACGGCCTTACATTTGGCAACCCTAGTCAAAAATTCTGGAATTTCTCTAGCAGAGTTAGTAGACCAAAGCTTTAAGACCTATCCCCAATTGCTCAGAAATGTTAGAGTTGAAGACCGCGATCGACGGGCCAACTGGAAAAACTGCGAACCATTAGTCAAAACTATAGAAGAAGCAGAAACAGCCTTAGCAGATTTGGGACGAGTATTAGTCCGAGCCTCTGGTACAGAGCCGGTAATTCGAGTCATGGTAGAAGCTATTAATCTAGAACTAGCAAAATCTTGGACAGAAAATATAGTTTTAGCAGTCCAGCAGCATTTATTACCTACTAAAGACTAAAACATAGATGATCCTAGACAAGCTACAAAATATCTAGGATCTCAAAAAAATCAGGAGTGTGCAGATAGCAAAAATATTTGCTATTCAAGCCAATGAATATAATATCATAAAAGTCAGAAAATAGTAAAAAAAAATGATATATATTTTGAGTATTATGATAACGTTAAAAATTTATGGGCAGAATATTAACTTTCTATCTAAGCAAGTAAATATTGAAACGGGTTTTCAGTGAATCTTTTGCAGTTAATGATGAAAAATATCTAGCTTGATCTAGTTTTCAAGAAACTGACTCCAAAATGCCAAAAAAACAAAAGTCTCAAAAGAAATTAAAAAAGAAAGGCAAACCTGCTACTCCCCAGATTAGCAAAAAGAAATTAGCTGCTAGGAAGCGCAAACGAGCCAAACAAATTCAGCAATTTATTGGTTCCTTGGCAACTTATGGTGGTCTTGGTGCCATCATTGGTCTTGTATTATTTTTTGTTGCAGAACCAAAAATAGGCCTTGCTGGTGGTTTTGGTCTGGCAGTTTTAGCTCTTTCTTTTAAATATCCAATGTTGGGACTTTGGGGATTTCTAATGTATTTGCCCTTTGCTGGTACTGTTACTTACTGGGTAGGTGACGGAGGTCCTATATTTCAGCTAGCCAAAGATGGGTTTTATATTCCTGCAATCATTGCTATTAGTTTGTGGTGCAAAAAGACAGGAAATCCATTCATTATTCCCAAATCAATAAAAAATCCCCTGTATGCTTTATTGGGCTTGTGTCTCATAACTTTATTCTTAGTTAATGGTGTACAACACTTTAACCCTCCCCAACCAGGAGATAAGGCAATTCCTATGGGAATATTGGGACTCAAAGTCATGATCGGCTACTTACCTCTGATCACGGGGGCTTATTATCAACTCAAAAGTAAAAAAGAGTTATTATTTGTTGCCCGTCTGACACTAATACTAGCTATTATCTGTTGCTTACTAACTATCGTACAATACCAATACCTTTCTTCTGGTAAGTGTAACGGTACTAGGGGTCAAACTGGAGACGCACTATTTAAGGCAAGCTTAGAAGCTAAATGTTTGGTAGGAGGTGCTCTAGTATTTAGTCCTAGTCAAGGCATGATTCGTTTACCAGGTACTTTTGTTGCACCTTGGCAGTGGGGATGGTTCTTGATTTCTAATGCTGCGTTTACCTTTGCAGTTGCTTTTAGTGACCCTTCTTCCCTCTGGCGAATGGGAGGGTTATTTGGTATGGCAGTAGTTTTTATTAATGCAGCTATTAGCGGTCAAAGAATTGCTTTAGCTTTAGTTCCCACAACAACAATAATACTCTTAATCTTAACAGGTCAGCTAGCTAACTTTAAACGGTTGATACCCATTGGAGCTGGACTAGCTGTTATACTAGGAGGTCTAATAGTATCTAATCCCGTAATTGTTCAAGAGCGGATAAATAGTTTTGTTGGTCGCTGGAATGCTTCACCGCCAACTGCTTTTATTTCAGAACAATTTGAGCAGTCTAATCATGCACAAAAAGGGTTTTTTGGTATCGGTCTTGGACGGGCTACTAATTCAGCCCGAGTTTTTGGTAAAACTAAATTAATTGAAACTTATTATCCTAAGTTAATCTATGAAATAGGACCTATAGGCACAATAGCAATGTTAGTTCTATTAACAAATATTACTGTTAGTACTTTTAAAGCTTATCGCTCAGTTAAAGATAAAAACATGCGCAGTTTAGGTGCAAGCTATTGGGTTTTTGTTCTCATAATTAGTTATAACACTTATTATTACCCTCTTGATGTAGATCCAGTTGCAGTTTATTACTGGTATTTTGCTGGAGTCATTATGAAACTGCCAGAAATTGATAAAATTGAACAGATAAAACTTAAAGAAGCTGAGGAAAATTGAGTTTATTCAATAATAAATTTGTGGAAATTAATTTTGTAAATTATTAAATTTCTCAAATTCATCAAGATTATTTCAGCCCTTTTTTTGTTTTACTATATATTTTCTATTATATGTTTTAAACATAGCATATTTTTTTGATTTTAGGTAGTTAAAAGAATAGATGTAATACACTTTGATCACATATTGATCCTAGATATAATATGAATTATATATTAAAAAAAAATCAAATTATATTTCTATTATTTTGGAAATAGATTGAAACAAATTAAATTAGCTAATTAAAAGAATTGAGCAAATTTATCAAGGCTATATATTAGTTGTGATATTTTTTAGAGAGATAGATTATAATATAGCCATACATAGTATTTTTTACTATAGAACTAGTCGTTTATTTATCAATAGTATGAAAAAAAATCTATCTGATCTATATGGAAGGATTTGATATTCTATTTATGCCCTTCTTTTTTATAGTTTGTTACTTAATTTTTGAATTATTGAATCAACAACAAAAAAAAGATAGGTTGTATCTGACGATTACCATCATTATTAGATATCTATTCATACCAAGTATATCTTATACATCAACCCCTATATTTTTTTATTCCATCCTTTAACAAAATATCTCAATCTTGAACCATGTTTAAAAGTAATTCTTGTGATGATAATTAAAATGCTCTTACTAAGAGTTTATTATTTGCCTTGATTTTCTTGGAAAACTTTTTCAAGAAGCTAGTTGTAGAGAAAAAAACTAGCAAATATCAATAAAATTAAACTTACTTTTAAAGGATAGCAGACTATGAATTTACCATCAATTTCCGTTGTTATTCCTACCTACGGGCGGGAGGAACCTCTAATAGATACGATCGCTGATGTTATTAAACAAGACTACCCTAATTTTGAAGTTTTAGTAGTTGACCAAACTGGGACTCATAAACCAGAAACTCAAGTTTATCTGGAAAAACAAGCTAATGCTGGTAGGATAAAATTGTTCCGCCTGACTTGGGCCAGCCTACCAGGAGCAAGGAATTATGCAGTCAGACGTTGTAGTGGCGAAATCATCCTTTTTATTGATGATGATGTACGTTTGCAAAAAGGATTTTTGGCGGCTCATGCTGGTAACTATATTGATCGCCCAGAGATAGGAGCAGTGGCAGGACGAGTATTTGATCGCATGAAATTAGGAGATTCTGGTGGAGAGTTGGAAATAGAAGATTTACCTCCAGAAGCGTCTGACCCTGGTATTGCTTGGTATCATATAGATTTGGTACATACGGTTAAAGCTCAACGAGTCATCTCAGCAAGAGGGTGCAATATGTCATATCGCCGAGAAGTTTTTACTAAATATGGTTTGAGTTTTGATGAGCGGTTTCGTGGCAGTGCAGTAAGGGAAGAGTCTGATTTTTGTTTGAGGTTACGACGAACTGGCTATCACATTTGGTTTGACCCAGAAGCTTCTTTAGTTCACTTGGGTGAAGAAAGTGGGGGTTGTCATGATATTTCTACAAGGTCTCTCAAATATCAAATTACTTTTTATCACAATCACTTTTTTATGGGATTAAAAAATCTCACTCCTCATCAATGTCTGCGTTTTTTTGGCAAATTATTTGATTGTCATGTGTTGGGGAACCCCCCTTGTTACAAAAGTGGTTCTCCTATAAAAATAATTACTCGCGGCGGTTTCTATATTCTTGGTTTTTTTAGTGCTGTTCAAACAAGGATTAAATCTATTTGGGATGACGGGCAAATTTATACAAAAAAAGTCAACACTCAAGAGTAATAATTCAAGAAACTCAAAAATTAAATAAAATTGTTTAAGAGTAGATCGCATAAGGTCGATCTTTATGGTTTTAAGCAAATACTAGAATTGTATAACCTGATTTTAGATAACAGTTTTTTTCAGCTTACTTGTAAAGATGAATTAAAACTTATTTCTTAAGTTTTCTCTGTAAGGCTTTTCGAAAATATACAGTTTGCTGGAAAATCATCTGTAATTTGGATGTAGACCACAATGATTTTTTTAAATATAATTCATATATATTTTTCCGTTGATCAGATATCCAAAAATACCAAGGTTTTGAAGAACCAATATAATGTATAATTCTAGCATTTTTCAAAGCGATATTGTCATCAGGTTTTTGAATTTTTCTTGGGCTTAAGTCCACTTGAAAATTCCATTTCCGATCAATTATTAAGTAATTCTGTTTGATTACACGATTTAAAGCGCTTTGGTCGTGGTATGGCAGCTTATCTCTATTTTTAGTTGCAAAATCAATTACTTTTGTTGAAATTTGTTCATTTCTCCATTTTTCTAAGTTAACAACCATAACACCACTATTAAAACCTTTACTTTTTACCAAAGTGCCAGAAAATCCTGAAGCAGCAATAAAGTAATTTTCTAGATCAATATTATATAGTTCTTCTAAGGGAGAAATTACAACAACATCAGAATCTAAATAAAGAACTTTATCTATATGCTTAGGGAGAATTTCAGCCATTATTAATCTATAATAAGTTGCATTGGAAACATGATCAGATACTTTTAATTTGCTAATTTTATCAAGGTTATTGATTATATATAAATGAAATGAACATTTATAATTTTTACTCAGCGTATCTAATTTTTGTTTTAGTTTTTCTTCCATAAAATTTGTGATTATATGTACATCAAAATGACTAGATAAATTATTTAATAATACAGAAGTGATTGCTACACCGAAGTGTTGTTGATAGTTTTGATCAAAACAAAATAATAGATTCATCATTCTTCTCTTTTATGCCCTGATATTTCTATAATCATCTTATCATAATAATAAAATATTCAGGCGGTTTTAAGGTAGGAGCAAGGAGGCAGAAGGAACAATAGTTAGAGCTATTTTTTTGAAAAGTATGTGATTTGATAAGAATTTAAGATTCCTATTTTGGAGCTAGGTTATGGCCCTAGATTTTCATATATAGTTAAATTTGATTCTAACTAAGGTTTGTTGATTAAATATCTGATAAATGTCCAACTATATATATATATATCAATTTGGTTTTTTTGTCAAAAAAAATGTGTCAGCTTTTTACTCCAAACTAACTCAATTTTGAGCTACAATTCCTATAAATATATCTTCTAAATCACAAAAAAATAACTATGAAAATATTAATCGCTAGCCATACCTATATTGTTGACCTTAATCGGGAAAAGTTACGAGCTTTAGCTAAACTTGAACCAGGTCTTGAAGTTAGGGTTGTTGTACCTCGTCGCTGGAATCCAAAAGGCGTACAAAGTGAAATAGTTGAAACTAAATTTATTGATGAGGGTTCTTTTAAAGTAATACCTCTTTCTAATTATAGTCAAAATAATCAAGCTTTGCTAACTTTCGGTCCCGAACTAATTAGTTTGCTACGAAAATTTAAGCCGGATATTATTCAAGTAGAACAGGGTTCTAAAGCTTTAACTTATGCTCAATTTATTACTTTTAATAAGCTTTTAGGACTCCAGGCTAAAAATTTATTTTTTACTTGGTGGAATTTACCTTATGAACTCAAATTTCCTATTTCTTACCTAGAAAGCTATAACTTGAGAAATACTGATGGAATTGTTGCTGGAAATAAAGATGGAGAAAAAATTTTAAGAAATAAGGGATACAAAGGTCTGATTAAAGTGATGCCTCAGTTAGGAGTAGATGAAAGTTTATTTAAACCAGAACCTCAAGTAGAATTAAGAGATAGTTTAGGAATTAAAGATGATGATTTTGTAGTTGGTTTTGTGGGTCGTTTTGTTCAGGAAAAAGGATTATTAACTTTAACTAAATCCCTAGCAGGTTTACAGGAAAAAAATTGGAAGTGCTTGTTATTGGGTAGGGGTGAATTACAAGCAACTTTGTGGGAAATAGCAACAGCATTAGGAATTAAGGAGCGTTTGATTTTTGTAGAAAGTGTTCCTCACAACTATGTACAAAAATATATTAATTTGATGAATACTTTGGTTTTACCGTCAGAAACTACTTATAAGTTTAAAACTTTAACTTCTGTGGGTTGGAAAGAACAATTCGGTCATGTTTTAATTGAGGCAATGGCTTGTAAGGTACCTGTAATAGGTTCTGATTCTGGAGAAATTCCTAATGTAATTGGGGATGTTGGTTTGGTTTTTCCAGAGGGAAATATTGAAGAGTTGAGGAATTGTTTAATGCAGTTAATGGAACAAAAAGAATTAGCCGAAAGTTTAGGAGAAAAAGGCTATAAAAAGGCAATGAGTCAGTATACAAATAAGTCTTTAGCTAGGCAATTATTAAGTTTTTATCAGGAGTTGCTGTAGATAAGCTGAAAAATAATAAGTGAGGCTGTAGCAATTCCCATAAGGATAAATATTTAACTAAAAAATTACTTGGTTTTAGGAAATATTTAATTAGGAACAAGTAAAGGAAAAAAAGATAGGTTGACTTCAAATTAAGAGAATTCCTAACTGATTAAATGAAGTATAGTATTTAAGTTCAGATAATCTGTTGAAAAACTTTTTCCTTTAAGTTTCTTTTCTTTCCTTCTGCTTCCTCTCAATGATTATAAATGCCAAAATTCTCTAAGCTTTAATGCCATTTATAAAAAGCTTTTCTACATTTTATTGAGTAGGAAAGTAGAGAAAAAGTAAAGTATCGCCTATTGCCAAAGTTGTTTAGCCTGTCTACAAATGTTTTCTATGTAATTTTCTAATGGTGTCTCAGGAGCAAAGTGTAAACAGTGAATATTCTTTTTTTCACTATTATTGATAATACATGAAAATCACGAAATTATTGAGAATGATCAGGACTTGCACTATCAAAAATTCAAACAATTTTGGCTTATTGACTCTGGTTTTGTAGATGTCTAACAAAATTAATTGTTAATAAAATCTTAGCTGTTTGATAAGTGCTAGGTATCTCTTCACCACTGATATATTTCTATTGCGCTATAGTTAAGTTACCAGAGTTACCATGTAGTTGTCTACATCTATTTCTCGTTTTTTTTATAGGCGATCGCTTCATCCATAACCACAAATATGTCTTCCAAGTAGATGCTACTCATAGTTAGTAAAAACTTGATATTTTTCCTGAAATGATTTCTCTAGGGTTGTCTTGAAGCCTATAATTAATTATTTAGTTGTGCTGCTCTACCACACATTTATCAGATTTATATTTGGGGCTTCTGTTTTTTTGACGCCAACTAACTCCAGCGTTTTTAAATAAATTATAATAACTTTGACAGGAGCGATATACTACTCCATAATACTGTTCAACGTGATCAATTAACTCTGAAATATTTATGCGTGTTTTTTGTTTTAGCCAATTCATGACAGCTTCACGTTGTTCCTTATTCAAGTATCCTGCACTACCTTTATATTTCAATTTTATACCCATTAACCCTTCTTCTCGATAACGTTTTTCCCAACGACTAATATAACTTGACTCAACACCCAGTATAGTCTGAATTTCCCGATGCTTAAATCCTTCAAACCGCATTTTTACTACTAAAGCTCGCTTTAACTCTCTGGGATCCGGATTAGTTGCTATAAAATCTTCAATTAACATAAAAACACAATGTGCTATTTTTATTTACTTTACTTTTTTATGATAACTTAATTGATATTTAAAGTTAAATGTTGCACAATACAAAAGCGATATTGTAGAATTTTATTGAATAATGCATTGTCCTTATTGTCAAAGTCATAAAATAGTTAAAAATGGCCATCGTAACGGAAAACAGAGTTATTTGTGTCGTAAATGTGGCCGTCAATTTAGAGAAAACCCTTGTCCTATCGGTTATAGCTCTGAGGTTAAAGAGGCTTGTCTAAAAATGTTCCTTAGCGGCATGGGGTTTCGAGCTATTGAGAGAGCCACTGGTATTTCCCACAACAGCGTCCTTAACTGGGTACGCCGCGCAAAAGTAAATGTTTCTGATCGGAATTCTGAAGCTTCTGAAGCCGCTCAAGTTGATGGACTGCAGATTTTTGTTGACCCAAAAAAATAACTTAGATATCAATAATTCTAAGTAGCAAAATACTAGGACTTCTGAAGTTGGTGGTAGGCGATCGCTCTCTTACCTTCACACTTATGATGCAGATAACTTCACCTCAAGGCCTATGCTATTCCCCCCTTTATCTCTCCCCAAGAGCGGAAACCAAAAGTCAAAGGTCAAAGGTTAGAAAAAAACCATCAGTTAGGTTTCACTTTGTTCTACAAAACCTAAATTTTTCGACGTTTTGCAGCTATTTAGTAATTTTCGTCTCCGTAGACCAGAGTAGAAACCCCCTTATGCAACCTCTATAATATACAAAATACAGAGTTTTGCCGATAGCAATGTAGTTATGAAACTACACCACCTACCACCTACCAGCTAAAATTTACCACCTATCACCTAATACCTAAAACCTAAAACCTAATACCTAATACCTAATACCTAATACCTAATACCTAAAACCTAATACCTAACTCACTGACTGACTGACATATCCACGCTCCCCAAAAATAAGGATGAGCTAATGGTTTACTCTCAATTTTTAGATTTTTTCCTAAATTTAATTCCCCTAAAATATCACTCCCTAATTTACTTTTTTGTAGTTCTCCAACTGTAATATTTCTGATATATTTCTGGGCTTTTCTTAAGGCGGCCCCTGCACTCATTCCTGACCGTGAATCATCTAAAAATTGCTCCATTAATAACATGGTTGCTAATGTTGGTACGCTCCACAAACTCATTATTAATGTTTGATTCCCCGCAACGGCAAAGGCACGACGCAAACCGAATACTCCTTCTCCCGTTTGCACGTCTCCTAACCCGCTTTCACAGGCGATTAAAATTACTAGCTCTGTTTCCCAGAGGTCAAGCCCGGCAATATCTTGAGCAAATGCCATTGTTGGGAATTCTGGGGGGAGTTGGCCACCAGAAAGCCAGGTGTTGGCACCTGTAAAAGCGACGGCGGAACCCATCATCGGGTTTTCGATTTTTGCTTGGTGGCGGTTGGGTTTGAAGGTCTCAAAATCCATGTTATTAACTGGGGGTTTGACTGGGGTCGTCTTGAGCTGCTGTTTCACTAGAGGGGCGATCGCTCTTAACTTTTCTCTGATTTTATTATCCCTATTTTCTGAGTTTCGGTATCTTTCAATAAATGCCAGAAACTCTTCATCCAGTAAACCATAATTTTTTTCTAATATCTCTACTTCTTTTCCCTGGGAAGAGGACAGTAACTCTTTCAACAAAGTCAGATATTTATCTTTTCTCTGGGAGTAATAACCGTGGGTGGCAACTATGAGCTGTTTGGGAGATTGACATTTGAGCAGGCGATCGGCAGTTGCCTCATTTCCCAGAAAAGGTTTGACTCCTAACTGTTGTCCAATAGTTTTGGCAAGATCAGCGGTTGCTTTCACTCGTGGAAATGTTATCCCTGCCAGAGTACCTAACATTGGCTGAACATTCAGACCAGAAACAGCCGGACTTTCTTTTTGTTGTGCCATATCTGGAGCATTCTGAGGCCAATCAAAGTTAGGGTCGGCCATAATTAATGGTGGGTTTGCTGTGGGTTTTGTTTTGATCCGACGCCGCAATAATTCTCGCCCAACGCTGACATAACTAATGTTGTACTCATCCTGCAATGTTGTTTTCCCATCATCTTCTGGTAAGATTTGAAATGGCACTAGGTTTAAATCACCATCGGGAGCTAATACTAGATGAGAGCAACCTGTTAATTTATCTCGCAATTTATCAAAAACTGCTTCTCGTAGTTCTTTCCCTGGTTGGGAGTCATAGATATAATGTTTTGTAGGTGTTTCTGTTTCTGTAGAATTTGGTTTATTATTCCACATATTCATCTGTTGTGGTAGTGGCCACTTTATTACTGAGTTTCGGTAAGTCGAAATTAGGCGATCGATATTTTCTGCTTCTCCTAAATCAATCATTTCTACTTCAGAAGGTTTTCCCCCAGCTAAAACAAATGCCAGATACCGGGCTTTTCCCCAACTCTTCTCCTGAACATCATAGACATCAAACTGCACAAATTCCAATAATTTTTCCCCCTCTGATAACTCTGACGCGACTGCCCGTATGTCTCCCATTTGTTGCTGTATTTCAATTTCTGGCATTTGTTGGGTTAACTTTCTTTCTAACTCATTACATTCTTTTTGCAGTTGAGCTAACTGTTGTTTGTGAGTTTCCCGTTTTTCTGGTCGGGGTACTTCATAGGTAAGTGTTAAAAGTTGGTCGCACTTTCGCCGCCACTGTGGGAAAATTTCTTGGAGTTGGGGATAACGGCCACTGAATACGGCTTGGTTTTGAGCGGCCATGGCTGTTGCTGTTAGAGATTTCCGTTTGAGGACGAGATTTAATGCTGCTTGTTTGGCTTCTGGGGAGTGGGGGAAATGTTGGTAGACTAAGGAGAGGAATGTCTCTAGGTTAGGTCTGACTTCTTGTTTGATATGGGCGAGGCGATCGCTTTCGGAGCTAGAAGCAAAGATAGCCTGGATAGTTTTATCTTCGATTTTGCTGGCTTTGAGCATCAGTTTGAGTGCTTCCGAGTATCTCCCTTGAGATGCATATAATAAAGCTAGGTTATTGAGGCAAGAGGCACGTTGTGGATGATTCGCAGGCAGGGCGACTTTGTGGATTTCTATTGCTTGTTTGTACAATGGTTCCGCTTCCGAGTATCTCCCTTGAGCACGATATAATTCTGCTAGGTTGTTGAGGTTGGTTGCCAGGGATGGATGATTGGCAGGCAGGGCGACTTTGTGGATTTCTATTGCTTGTTTGTACAATGGTTCCGCTTCCGAGTATCTCCCTTGAGCATGATATAATTCTGCTAGGTTGTTGAGGTTGGTTGCCAGGGATGGATGATTGGCAGGCAGGGCGATTTTGTCGACTTCTATTGCTTGTTTGTACAATGGTTCCGCTTCCGAGTATCTCCCTTGAGCAGAATATAAAACTGCTAGGTTGTTGAGGTGGGTTGCCAGGGATGGATGATTGGCAGGCAGGGCGATTTTGTCGACTTCTATTGCTTGTTTGTACAATGGTTCCGCTTCCGAGTATCTCCCTTGAGCACGATATAATTCTGCTAGGTTGTTGAGGTTGGTTGCCAGGGATGGATGATTGGCAGGCAGGGCGATTTTGTCGACTTCTATTGCTTGTTTGTACAATGGTTCCGCTTCCGAGTATCTCCCTTGAGCACGATATAATTCTGCTAGGTTGTTGAGGTTGGTTGCCAGCTCTGGATGATTGGCAGGCAGGGCGATATTGTCGATTTCTATTGCTTGTTTGTACAATGGTTCCGCTTCCGAGTATCTCCCTTGAGCACGATATAATTCTGCTAGGTTGTTGAGGTTGGTTGCCAGGAATGGATGATTGGCAGGCAGGGCGACTTTGTAGATTTCTATTGCTTGTTTCAACAATGGTTCCGCTTCCGAGTATCTCCCTTGAGCACGATATAAACCTGCTAGGTTATTGAGGCCAGAGGCACGTTGTGGATGATTGGCAGGCAGGGCGACTTTGTGGATTTCTATTGCTTGTTTGTACAATGGTTCCGCTTCCGAGTATCTCCCTTGAGATTTATATAAACCTGCTAGGTTGTTGAGGTGGGTTGCCAGGTCTGGATGATTGGCCGGCAGGGCGATCTTGTCGATTTCTATTGCTTGTTTGTACAATGGTTCCGCTTCCGAGTATCTCCCTTGAGAAGAATATAAACCTGCTAGGTTGTTGAGGTCGGTTGCCAGGGATGGATGATTGGCAGGCAGGGCGATATTGTCGATTTCTATGGCTTTTTTGAACAATGGTTCCGCTTCCGAGTATCTCCCTTGAGATTCATATAAACCTGCTAGGTTGTTGAGGTTGGTTGCCAGGGATGGATGATTCGCCGGCAGGGCGATTTTGAAGATTTCTATGGCTTGTTTGTACAATGGTTCCGCTTCCGAGTATCTCCCTTGAGCACGATATAAATTTGCTAGGTTGTTGAGGTTGGTTGCCAGGGATGGATGATTCGCCGGCAGGGCGACTTTGTGGATTTCTATGGCTTGTTTGTACAATGGTTCCGCTTCCGAGTATCTCCCTTGAGCACGATATAATTCTGCTAGGTTGTTGAGGTCTCTAGCCAGGGATGGATGATTCGCAGGCAGGGCGATATTGTCGATTTCTATTGCTTGTTTGTACAATGGTTCCGCTTCCGAGTATCTCCCTTGAGCACGATATAAATTTGCTAGGTTGTTGAGGTTGGTTGCCAGGGATGGATGATTCGCCGGCAGGGCGATTTTGAAGATTTCTATGGCTTGTTTGTACAATGGTTCCGCTTCCGAGTATCTCCCTTGAGATTCATATAAACCTGCTAGGTTGTTGAGGTTGGTTGCCAGGGATGGATGATTCGCCGGCAGGGCGATTTTGAAGATTTCTATGGCTTGTTTGTACAATGGTTCTGCTTCCGAGTATCTCCCTTGAGCACGATATAAATTTGCTAGGTTGTTGAGGTTGGTTGCCAGGGATGGATGATTCGCCGGCAGGGCGACTTTGTGGATTTCTATGGCTTGTTTGTACAATGGTTCCGCTTCCGAGTGTCTCCCTTGAGATTCATATAATAAAGTTAGGTTGTTGAGGTTGGTTGCAACTTCGGCATGACTTTCTCCCCAGAGTTGTCGCGCTAACGTCACCCCTTGTTCGGCAATAGGTATTGCTTCATCATATTTACCGGCATTGTAGAGTTCCATTACTTGAACATCTAGCTTTTCTTTTGCCTCCATCATTTCTGCCAATTCGTTAGCCAAGCCTTGCAACCATTTTGCATTTTTCTCCCCATCTTCTACCATTTTAGCCGCCACTAACTCCATCGTTTTGACAAAGGCTGCATCTAATAATTGAGAATTGGCGTGCAAAATTGCTTGCTCTTCCCCACTAGAGCAAGTTAATAGTTGGTCTATTAAATCTAGGCGAGCTTTAAGTTGTTCTTGAAATTGTTCTTCAGTCATATTAGTTTCTCCTTATTTGAATAACCCTATCATATCCGATCAAACACTCCCGTGGTTGTAGTTGTTCTTTTGCACCCTAATATAGACCTCTATCCATTCAGGAAAACCAAGAAATCTTAGGGACTACTGGGAGTATCTTACTTCCATTCTTATGATATTTCAATAAGTTCAAAATTGCAACAAAAAATCCATATTGTTCTACATAATTCTACCTAGCTCTACCTAGTTCTACTTACCTATATATGATTCTAAACAAATCTATTTTGATTTTAAATAGACTTATTTACTATTATTATTTTATCCACAAAATCTGCCTACAAAAAATTATATCTAACTCTAGTTAACTCTAAAGCCTACTATTTACATCCCTTGAAAATGCAATTTAAAATAAAAGTATACTTTCCCAATAAATCACGGAATAAAATGTCTAAACCAATTAAAATCTTATTAATTTCAATCTTTGCCGGAAGTATTTTCAGCATATTATCATTGAGCAATAACCAAAACAGCAAAGAAATTAGTCAAGCCCTTGAAAGTGGAGTAACTATGACATCCACCATAGCCAGTTTACTAATAAGCTTAAAAGATAGCAATGAATAGTACTGCTCAAACTCAAAAGTCAACACCCCTGTTTTAGTTATAGAAAATTAGTTGTGAAACCCTATCACCAGGCACCAGCCACCTAAAACCTAACACCTATTCCTTATTTTTCAGCTACTTAAGCAACTTTCATGTCGCTAGACCAGAGTAGGGATGTTTCACTACGCGACATGAAACGCATTTTTGTGATGCAACCTCCCTACAAAGCTTTAGTTATAGAAACTTAGTTATGAAACCGTACCACCAGGCACCAGCCACCAGCCACCTACCACCTAAAACCCAACACCAACTACACCTAAACCACATCATAAAACATATACCACAAAGTAGAGTCTGACTCAGCCTGAAAATAAGTCAAAAATTCCTGCAAATGCTTTCCCTCTAACAACAAAGGTGGTTGGTCTCCTTGTGGTAACCAACTTAACCTTGGACGTTCCTGACTGATCCCCGCTATGATCTCCTCAACCCCTGGTTTACCATCCAACCTAAAATAATCAACTGGCGCCCCCTCCATAGGTAAAGACACCACACCCGCATCAAAAATAGGCAAAGCTCCCAAAAATGAAGGAGACAAACAATAAAACTCACCAGAAGTACCCCTTTCTAACAGAGTTAAATATCCCCGACGTTCCAACCGTACCTCAAACTTAATTTCACTATCTAGAGGCACAGTCTTAGGATAATGAGGATCAACCGTATACATATCCATTGTGCTCATCCCTTGAAGAACAGGACCCATTTTATTAGTTGAAGTAGCCATATTTTTTAATTGATACCAGGGATAAAGAACTTCACGGAGCCACTGTCTAGCAATATTAACTTTATCTCTTGTCGCGTCATTAAAATGACAACCTTCAACCTCCAGTTTTTTAAATATTCTCCTCAAAGCATCCCGCATAGTATTATTATGTCGTAAATTTGTTAATAAAACATCAGCCAAAGCTGCATTATTCAAATCATCATTATTTATTTTAAACCGTTCAATAAATACAAGCCTAGTGTTATCTTTAAGACTCAACTTATCAGCTACTTCTCCCAGAAAAGCAACCTCATTATTTTTGTAACTTTCTTCTGGCATCATCAACCATTCCTTTCTTATAGGTTCATTTATAATGATACTTCAATAAAATCAAAAAATCTACAAAAAAACTACATGACTCTACATAACTCTACCTATCTCTACCTATCTCTAACTAGCTGTATATCGCTTAAAATTGACTTATTTTCACTTTCAAAAGATTGATATTCTATTATTATTATCTACAAAATTTACCTTGATAAAACTTCCAAATAATTCTCATCAAACCTATTTCCTACTTACAGCTTAGTCAAACCCATCCCACTGGACTCAAACCTAAAAAACTAACACCTAAAACCTCAACCTCTGCTCGTACCTTACCCTTCCCTGAAACCGAGCTTCAACCCCGTGAATTCCCCCCTTGCCCTCCAAGGGGGGGTTGACTTTGAGCTTATGTATAGCGCTAAACCACCTGATAATGCATGTACCATAAAGTAGAGCCTAACTCAGCCTTAAAATACATCAAAAACTCCTGTAAGTGCTCTCCCTTTAAAAGCAAAGGTAGTTGGTCCGCCGCCGGCAACCAATCTAAGTTTGGACGTTCGTGACTGATCCCTGCTATGATCTCCTCAACCCCTATTTTACCATTCAACTTAAAATGATTAACTGGTGCCCCCTCCATTGGTAACGATGCTACGCCCCCATCAAAAATAGGTGAACTTGCCAAACACGAAGGAGACAAACAATAAAATACGCCAGAAGCACCTTTTTTTAAGAGAGTTAAATATCCCGAACGTTCCAACTGTACCTCAAACTTAACCTCACTATTGAGAGGTATAACACTGGGATAACGAGAAACAGTTTTAGACGTATCCAACTGTGTAATTCCTTGGATAACAAGACCCATTTTATCAGTAAAAGTCGCCATATCTTTTAATGCATGCCAGGGATAAATTATTTCACGCAACCACCGTTTAGCAATTTTAACCTTGTCTCTTTTTGCTCCCTCAAAATCACAACCTTCAGTCTCCAGTTTTTTAAATATTGTTTTCAAAGAGTCCCGCAAAATAATATCTGATGTTGCTTTTTTGCTAGCATTCTGTAATAAATTACTTGATAAAACATCAGCCAGTTTTTGATTATTCAAATCATCATTATCTATTTTAAACCGCTCCGTAAACACCAGCCTGGTTTTATCTTTAACCATCAATTTATCAGCTATTTTGTTCAGAAAAATAGCCTCATTATTTTTATAACTTTCCTCTAGCATAATCAAATTTTCCTTCTTGATAACTTTGTCTATAATTATATTTCTACAAAATTGAAATTGACACAACAATTATACACAATTCTACATAAACTTACATAGGGATGCATAACTGTATTTTGATTTAAAACAATATTTTTTATATCATTATTCATTATTTGTACTTTGATCAAAAACTTATTTAACTCTAACTACTACTATTTACATATCCTAAATTTTGAAATTAAATTATAGTATATTTACCCAAGAATTAAGATCATAAAACCTATAAATTAATCAATTTTTATTAATTTTAATCTTTAGTGGAAGTATTTTCAGCATTTTCTCAGTCAATAATAATCAAAACTCAAAATAAATTAGTCAAGCTGTTGAGCAGATAAAATAACTATAACATCTAACATGACTAGTTTATTAAGAATTTTAAAAGACGCCAATAAAAGTTTTCCAAATATTAATTATTCAGCCTTTGTAGCGCAGTTCAAGAGCTTAAGAAAATGTAGTCAACTCTTAATAAAATATTCTTATCTCATCCTTTTCATTCCTTTTTATCCTTTTCCTCTTTGATAATATTTTGTATTCCCGACTGCTGCAAAAAATCTAAAGCAGATTTAGCAGCCGCTTCCTCTGCGGCCTTAATAGATGGTCCTTTACCTACACCAAGTTTCTGGCCTTTAAACCAAACTTCGGCAAAGAAACGTTCGCGATCGCCATAAATCTTATTTACTTCGTGAGCTTGATAATTTGGTAACGTTTTGTAATAACCTTGAGTCAGCTCTTGGAGAGCAGCCTTATAACTGTGGCAAGCGGGATCCTTGCGAATTTCTGCTATTAACCTTTCAAAATGAGAATCTAACCAAGGGCGGATCAACTCTAAATTATTAGTACTCAAATAAAGAGCACCCAAAACAGCCTCAAAAGAATCTGCAAGTCGACGCTCTCTTCCAACTTTATCCCCTGCTGCACTTTTGGATACCAATAAATAACGACTCCACCCATACTTATCGGCAATTTGTGCCAAAGAGCGATCGCTTACTAAAATAGAACGAATGGCAGTAAATTCTCCTACTGAACAATTAGGATAATTTTCCAACAGTAGTTGTGCCGCCACAAGCCGTACCACTGCATCCCCAAAAAACTCTAGCTTTTCATTATTATGTGTTGATGAAACTGTAGAGTGAGTTAATGCCAAATCTAATAAATTCCATTTAATCAAAGCTTGTTGAGAAATAGATAATTTTTCAACTAAAGATTTAAGTTGCCTTTGGCGCGAATGATACATTTGAGTCATTATTCTGATGCTTTTAGTCTCTGCTGCTATATTTTTGTGACTAACTTCCCCAAGCTCACCCATAAAAATTGTACAAGCTTCGGAGCTAGCCTCCTGCTTCATTGAAAATCACTGACCGAAGTCTGTAACCTTTATTTGTTCACAGACTTAAAATTTCTGAAAACTGAACTTACTGATACAAATAGTTTTCTAAGTTGACCACAACCTTAAAAATTGGTGTCAACCCTACTTATCAGTATTGAGAACTTCACTTCTGACTTCTAATTTCCCGCTTTCTGACCTCAGAAGTATCTCCACCAACAACAACATTCCCAATACGCAAACTCGGACCTCCACAACCAACAGGTAAACCATTTTGCTCACCTTTACCGCAACCGCCAGACTCATCCCAATGAAAATCATCACCGATCGCTTCAATATCTGCCAAAGTATTAAACACATTTCCAGAAAGAGTCACATCCCTAACCGGTTCAGCTAACTCACCATTTCTAATCATCCAAGCTTCTCCAGCACTAAAAGTAAATATTTCCCCATTAGTCATGCCACCAAACCAGTTACAAGCATAAACTCCCTCCTTAATATCAGCAAATAAATCTGAAACAGGAGTATTTCCTTGTGCTATCCAAGTGTTAGTCATCCTCACAATAGGTGGATAACGGTAGTCAAGACAACGTGCATTACCCGTAGGTGCCTCCCCCAGCTTTCCAGCAGTCTCCCGTGAATGTAAGCGCCCTACTAAAACCCCATCCTGAATCAACTGAGTGGTAGTTGCTAAAGTACCTTCATCATCATAAACATAACTACCCCGATGAACTTCTTCCCCAGCCCCACCTAATAAAGGCTCTACCTTCGCACCATCAAATATTTGTAAATTTTCCGGACCAAATACTCGACCAATTGTCATCACTTCCAGTAGATCAGGATTTTCGTATGCCATATCCGCTTCCGAGAGATGACCAAAAGCTTCGTGAACAAATAAACCTGTCAGAATAGGGTCAATAACTACAGTATAAGCATTACCTTGAACTATGGGTAAAGCTAGAGAATTAACAGCTCTCTGAGCAGCACTACGAACTTGTGCATCCAAATTAGTTAAATCTTCATAAGCCTTGCGAGAACCAGTAGTTTCTCTACCCGTTTGTACAGTATCCCCATTTCTAGCAGTAGCAGCAAAGCGCATTTCCATATCTGTCCAAGATTGTTCTAATATCGTTCCTTCCGAAGTAGCTAGAATAGTTTTTTGGGTACTATCCCCATAACGCACAGACACATTAGTAATTCGAGGATCTACACTCCGCAGCACCTGGCCATAATGTTCGCATAGTTCTTTTTTACTAGCTAAACTTATGTAACGAGGGTTTTTTCCTGTGAGAGAAACCACATGAGTTTCTTGAATAATTGGTATAGGAGCTAGAATAGTTTCTTCTTTCCCAATTAGTTTAGCCGCAGCGATCGCCTCTTCTATTCTATCTTTCAAAGTATATATTTGATTAAAACTGGCAAAACCCCAAGCTCCTTTATAGCAGGCTCGTACTTGACCGCCAATAGAAATACCTTCACTCAGAGTTTCTATTTTGTGGCCTCGCAAAAGAATATCTGTTTCTTCCGACTTTTCTAAGCGAATAGCCAAGTAATCTACTTGAGAGCTATAATCACTGAGTAGGTCAGACAATAGATTTTTGGCTTCAGTTAGTGATATGGGCATTTATATTCCAATAGTTTTATGATTAATATTTGTACAACATCAACTTTGAATGTAAGGTTTTTTTTGGTAGTTATTTAACTATTAGAGCTACTCTGATGATTTCATACCTCATAAACTTTAGTTTTATCAACCGCAGTTTGATATAAAACGTATTAGTATATAGACATTCCCTTAGTCACTCCCAAAAAATAATTTTCGGGAAGCTTAACAGTTGCTATAAATATTATAAAAATTATTTTCATAACAATCTACAACTCATTTCACCTTATCGAAAGGAAAATACTCTAGAAACAATACATATTGGCCGTCCTCAAACAGGAAAACCTCAACCATATAAACACAAAATTCTAGAATACTTAAAGCTAAACCAAGGATTTTATCCTAGAACAACTGTGTCAAAAATTCACAACAGATACAGGTATTAAAGTGAGCATTCCTATAATATTTCGTTTCTTACAAGGACACAAACCCTCCTCGCCAAAAAAACTAAGTACAGTACTCAGGCTAAAACTGAAGCTGTACAGGAGTTAATAGTTGAGTTGAGTATTGCCTAGCGTTCGCTCTAGTAAAGGTCACAAACTTGTCTTTATTGATAAAACCCGATTAAATATAGGCATGATACCTGATTATGGTTAGGTAGAACAACATCTGGAGATAGAGTATATAGTCTAGCACCCTATCCTCATGGTCAAATGATTACCCTCATCGGAGCAATCATGTTCAAACAAATCCTCAACACTATGACCATCAATGCACCGAACCAGTGACAAGGTATTTAAAACTTTTATGGAAGAACTACTGGCCCCTGAATTATGGCCCCCGAAAAGTTGTGGTTGGAGATAATTTGCCAGCTATTTGCTAGCTCATAAGGTTAAGGGAATTTCTGAAGCTATTGAAGCAGTGGAGGCGAGATTCATTTATCTATTTCCTTACTCTCCTCAATTTAACCTTATTGAACAATAGTGGTCAAATCTTAAAGCCCATTAAAAAAAATTGGCCACAACTGGTGAACAATTAGAACAGGCGATCGCTACTTTGATGTATTTAGTCACTCCTAAAATGTTAAGCAACTGGTTTACTCACTGTTATTACTGTAGTCTTTTGTTATGAAAACCGCTATAAACGTATAATTTTTCTTTTTTCCAGAAAAATATTTTTTTTGCTTATTATCATCATTTAGGCTATTTATAATTTTTTCTGTCCTATCTAAAATTAATTCTTGTCCTGTTAAAAATTAAAGTGAATTCCTAACATTTAAAAAGTCTTTGTAGACATAAATAGTATAAAGTTAGAATAACTTATTATTCTAATTTTAATCTTTTTTTATGCCAAATTCTGGTTTTATGAATCATTTTTTTATTTGACCTATTCCCCCTTTTTTATTTTTTTTTCGGATATAATTTGAGCATTTTTATTAATTTTTTTCAATTACTGAGTACCAATACCGATAACTATTTTAGTTTCTTTTGGGTAGTAATTTATATACTCTAACATTTGATTCATTAGTATATTTTTTGATAAAATAGACCCTAAAATTATAGCTTAATTTTTATGTAGCCATACAACTATTCATTCTTAGGATATTATAAAGACAACTAAAAGAGAAAAATTTATTTGTGGAACTATTCTCAAAAATAGACGCAAAAAAAAGTACAGTAAAAAAGATAGTAATCCTTTATCTTTTGCCGATTTATCTGAGTTAATAAATAATTTGCAAATTGAATAGTTAAACAATTTGCTGGAGAAGAAAATTATTCGTCATGTTAAGCAACATTTTTTATAAAATTAACTTCGAGAGTAAAAACCTGTACAAAAAGATAATATAGCAGTAACTTGTGAACTATTAATATTCAAATTTGACTAGCAGATAAAGGTTAGAAGGGAGAAGGTTTTTTCTAACTAATTTGATGATTTTAATTCATAGAAATTTTAGCTTTTTTCTTCCTTCTAACTTCCTCCCTCTTACTTCTGAATTAATATTGAGGTACAGAAGAATCTATTTCCTTACTCCAAGCAGTAATTCCACCCTTGAGATTAGTACCCTCAATACCATGTTCTTTAAGAATACCTAAAGCTTTAGCCGATCTCCCCCCCATCTTACAATGAGCAATTAAAGAGCGATTATTCATTAACTCCTTCACCTTTGTCACACCAGGGCCCTGCTCAATATCTGGCAATGGTACTAAAACAGACCCAGGAATTTTGGCAATATCATATTCATTGGGGTTCCGTACATCAACTAAAACAAAATCATCCTTCTTCCCACTATCAAATAATTGCTTCAAATCTTGAACTGTCATTTCTGGAATAGCCATTTTAGTTTCTGCCTCCTGTGCTTTAGCTTGAGGAATACCACAAAACTGCTCATAATCAATCAACTCTTCAATAATTGGTCGTATCGGATTAGGACGCAATTTCAATTCTCGGAAAGTCATATCTAGGGAATTATAAAGTAACAATCTACCACTCAAAGTCTTACCTTTACCCAAAACAACTTTGATAGTTTCCGTTGCTTGGATCACCCCAATTATTCCTGGTAAAATACCCAACACCCCACCTTCTGCACAAGAAGGTACCATTCCTGGGGGTGGAGGTTCAGGGTAAAGGTCACGGTAGTTCGGTCCACCTTCATAATTAAACACAGTTGCCTGACCCTCAAAGCGGAAAATTGAGCCGTAGACATTAGGTTTATTCAAAAGAACACAGGCATCATTAACCAAATAACGAGTCGGGAAATTATCAGTACCATCAACAATCACATCATAAGACTTGAGAATGTCAAGGGCATTTTCAGCACTTAACCTGGTTTCATAAAGGTCAACCTGACAGTAAGGATTAATTTCATGAATCCGATTTTTAGCAGATTCAATTTTTGGCTTACCCACCCAGGAAGTACCATGAATAACCTGTCGTTGTAAATTGGAACTATCGACAATATCAAAATCTACAATTCCAATATTTCCAATTCCTGCTGCTGCTAGATATAACAATAGTGGAGAACCAAGACCTCCCGTGCCTATACATAGAACACTAGCTGCCTTGAGACGTTTTTGACCATCTAATCCTACTTCCGGTAGAATCAGGTGCCTCGAATAACGTTGATATTCTTCTGTATTTAACTGGATTTGTTCCAGATTAGGATTTAACATGACAATTTTTGCCTAGATATTTCTTAGATAAATTCTGTGAACTGTTTTCCTACTAAACTGGAGATAATAGCTGAAATTCATTAACCCTATGGAATTCAGTTATCTGTTTCATAGTCTTAATGTCTCAGCCTTTATATAATTTAAAATGACTTTTTGAAAAAGCATTCAAATTTTATCAAATTTTTTTGAGCTATTGCGATAAATTGCTAGGAATATTAAAGTTAGCAACTACCTCCTAAAATTATCTACATTAAACCTGCTATATAGCTTATTGCTTATCTTTTATTTTAATAATTTTTTCTGGTTGAAACTGGTGATTATCATCAAGAGACCAACAGAGAAAGTCAATAGCTTGGCCTTTTTCCACTGAGATTATAACATAGGAATATTCTGGCCAAGCATAGGTACGGTCAAATTCTGAGGGGATAGCTACATGGTTTGGGTGGGAATGATAGATGCCAATAATAGATAAGTGGCGTTCTCTTGCGGACTTCATTGTTTTTAGCATCAGTTCTGGGGATATGGCATATCTTTTTTCTTCTGTAAATTCTGTTTGTTCTGGCCAATATTCATCTGCTTCTGTTTGCCAGGCATTTTCAGCAGGCCAGACTTCAATAACTGTTTTTGTCTCTTGGTTTTTCTGACCTAATAGTAAACCACAGCATTCATTTGGGTAAGATATTTCAGCATGAGTCAAAATTTTTTGAAAGTAGGAAGAGGAGAGTATTAAGGGCATCTGTTTTGAGAGGTAGGAAAGCCGAATGTGAGTTAAATAATTTTTGTGTACAATCTATTGAATAAGATTTTATGGTTTTTTTCTTCTTCTTAAGGTATTTATAAGACTGTAATCTCATCAATTTGATAATTGCTATATCTTCTGCTTGATTTTTCAATGAATATTAGTAGAACTTTTACCTTGGCATTCAAATTCAGGTTTAGCGATCGCTTCGAGCTATAAATACTACATTTTATTCTCACAAATCATTCCTAATTGCTGTATCAATATTTAATTTTATTTATTAAGTGATACTTTCTTGATGTTTAATATTTACTATTTGGTACAGTTATTTTCTAAGCCTTTTTATTTTCCTGAATTATTTTTTTTTTAGTTTTTTTGATAAAGTAACCATTATATTTACCCTAATAAAAATTTAGGTTTTGCACATCTAAAATTTTATATCTTTTGGCATTTTATTAGCCAGATTTTATTAATGTATACATCGTTTTTATTGAATTATAGTAATCAAAACTTTTAACATTAACCAAAAGTTAAATTTCAACTGATGGAGTAACTTATGGTAATCAAAAACCAAGTTTATTTCATGGTTATGATTGGTAAAAATCTATTTTCCTTGTTTAATTAATGAGGCAAAAACTGGTATTCTTTTAATATTACAATTAGGGGAAGGGAAAATTATAATTAAGCCAAGGGAACGAAAGGAATTTTACGATAGTTATTTTGGCGATTAAAAAAAACCATGGAAAAATGTTTCGATTATTTTAAGAGGATATAGATACTTTTATTTACCAGAAATAATTGATTTTTTTGAACTTCAAAATGTGTAATACTCTTTTAAATTTAGTAGTAATTAAGTCTTCAAAATAAGAATATATTATTTATTAGATATAGCTCGATTAAATTATAATAAATATCATCAAAAAGTTCCTTGATTTGATAATATTTATTACCTTAAAAAAAAAGTTGGGATAAATTTAGTCAAATTAAATATTGCTAAAATTAGATTAGCTATAAAAAATTATAAGCCTCAATTTTTATTCACAAATATGGATATAAAAACTCAATAAACTTATAATAAATTTTATGCTCAAATAGCAGCAAATTTAGATAATACAATTAAATAATAAAAAAAACTTCATAGATATAGGTTAATTTTTTATCAATTTATTGGTGATAAATTCCGTTTATTTCTATCTTAATTAGCTTATATTTTAATATTATAAATCAGAGAATTAGTATCACAAGCTAGATTAGAAAAAGCTCAAATTTATTCAATGAAAGAAACGTTAATAAAAATTGCCAACCGTATCAAAGTTATAACTCATGTAATTATGGTAAAACTAATATTAAATTATCCATTTTAAGCAGAAATAAAACTGATATTACAAAAATTATTAACAGGAAGACAATTAATTTATTCTTGAGATGAGTTGGTTATAGGATTACTATGTCTAAAAGAGATTTTTAGAAGGTTGTTTGAGGAAAATAACTGTAAATTTTTAAGTCTTGTTCTTTGATTAATTTTGATTATCGATCCTTAATCAATCTGTTTATGTTTACTTTTTTCCTTTAGTTTTTTTTGTTCATGAATAATTCAGGTTAGCTAATTTTAGTAAAAATGAATTATCACAACATCAATTTGCTTTCTAATGTCATGAATTCATGACTTATTCTAGGTCTTATAGCACCAGCTTGGTTTATAAATTATGTAAACATTCAACTCTTATGGCATAAGTTTAGAATCAACATCACAATTATTTAGTAAAGCTAAATCAATTATTTAGGAAGATTATGAGTATTACTTGTGATTTATGTTTCTACAACAGAAACTCAGAAAAAAACAAATTTTGCGAAGTTTGTGGTTCAGAAATTAGACTATCAACTACTTTATTGAAAACTCAAGAAAAAAGTATTCAAGAGGGAGAAATACAAACAGCTATCCAAACAGACAAAAACACAGTAAACCAGGATAAAGATATTAATCAAAATATTAATAACTACTTCCTAAAAACACCGACATATATCAATAAAACTACTAGTCAAAATCCAATTATAGAAGCAGATAAAAAAGTAAATATGACACCTAAAAATGCTATTAATTCTACTCTCATCAATAGCAGTATTGTTAAACTTATCCCCAAACAAATAGGTGCTCCTATACCAGAATTTATTATCGATAGCAATAATGCCATTATTGGTAAATTTAACCCAGAAATAGGACCAGTAGAAATTGATTTAGATGGATTTTATGGAGACAATACTGTTTCCTTAACCCATGCAGAAATCTATTTTAAAAATAATCAATGGCAGATAAAAGACATGGGTTCTACTAATGGTATTTATATCAAACATATAGGAAAAACTAGGTTTGGATACCGTATCAATAAACCAGAAATATTAAACTCAGGAGATGAAATTGCCATAGGTAAAATTAGGTTACTATTTATAATTAGTTGAACGTAACTATAGGATGGATATTGTTGATAAGTAAACATTGAGCTATTAACTATCAGCTCTCAGCAATAATACTCTGCTTTTGTAGTAATATTTAATACCAATCATCAAAAATAATGTAAGACTTTAGACCTTACTAAATACTTCATTTATTAAGTAATAAGTAAGGTTTAGTAATGTTTTTACTTAAGTAAAGAACAAAAAAATTAAACAATTAATAAATTCATTTTTTTTTTGAAATTGATGTCAAGAACAATCCCCCGTAAATGATTCAGTCCATAACGAAAAATACTTTTTGCTCTAGGAACGTATTTTTTAATTTTTCAGGGTATTTGTTCATGTAACCATTCCTTAATTAAAATTGCCCAATATAGAGCCAAACTAATTAACGCGAATAATTTACTCAGTCTTTCAATTTGATTAAAATGAGTTAATTTCAAATTGAATTCTCTAGTTTTAAACATCCCGAACAGTATTTCAATCTCCCGATCCCTGTGGAAGCTGAATCATTACTAATCACAATTAGTAATTCTCCATCATCTAACTGTAAAGCTGAAATATAAACTTGTCTGCCCCAAACCCATCATTTTCTTGAAATAGTTTAATATTCCACAATTTGAAGATGAGCAAAGATAATTAATGCGGCTCAACTTTTTTACCCATCACCAATATTATAATCTGCCTTTTACCTCAGCCAAAAATGAATTTGAGGTTCAATTCTTAAGTAAGTTAACCACTGTTTAGGGATAAACTCTCTATCACCACAAAAATACAATAAAAATACAATACTTGAGCATCGGGAAAAATATCCTAGAATTTATCTAACACATTCATTCTTTCACAAGTGTTATGAAGGTAGCGATCATAAACTACTCCCCTATTAAAAGTAACTAGATTTCAACTTATAAATCTATCCTACTAATAGTAAAATGATAATACTATGATCAGCGTTACTCAGTATAGTTAATTGAAAGAAGATGTTAGTAAATTTGAAGAATTAAGTGACATAGAATGGAAGTTATTTGAAGATATTTTTTCTATTTCACCAGAAAAAAGAGGTAAAAGTATGCCTGATACTCCATTTCGATATATACAATCATACCCTTCTCACTTCCTAAATAACAGGTTGTCCTTATTTTAATCACTTGGGAAAGGCAAAAAGAAACCAGGAAATGCGATCAAAATTTCTGTACCTCGTTTTCAAGAAGAGGGTTGTTTTGCCTAGTATCAAGGTAAATATCGTCGCCTAGTTGTAAGATGGGAGGTTATTTCTGCTTGTATTGAAGCAATTGTAGCGCTCGCCACTATACTTATGTGGATTAATTGCATTTTATTAGTGGGATAGGTTTATATAATAATCTGCCCATTGGTTGTGAAAATTTTTATCACAGTAAACTAGAAACGACTAGAATTAATATTATAAAGACAACTATACTTTATAATATGGATTATGAAACCGCCCGCCAATTTCTCATTGACCAGGGAACTGCTCTAGAAACTAAAATTAACCCAGATGCTTTTCTCATGCGTCTCGAACAAGGCAAACCCCCCATTCCTGGTCAAGTAACTAACATTTTGTTAGCTCTAAAAATATCCTTTGAAACATTACAAGGCGACCCCCTTCTAGACCGAGAATTAGTTGCCGGATTATATTTATTAGCAATAGAAAGTCTGAAATTATTTGAAGCAGGTAGACGAAAAAGAGTTATGTGGCCACCACTTTTAAAAGAAGATATCGAACGAATTACAATTGCCGTGAAAAATATTTTTTCTGGAGTTGTTTCTAAAGTAAAATAATACTTTAGATCAAATCTACTTGCTTTGGAGTGTTATTGGAAACTGGGTTTATGGGAGGTAGATATAATAGAAAAATAATAAATGTTTTTTACAGTTTATTTAGTAGGGGAATAGGGAAGTGGGGGAGTAGAGAAGAGAAGTAAAAATTTATAAAATTAACACTTGCTAATAATTATCAAAAAAGCTATTTATTATGCTTGTGTTAATTACTTAAAAATTGAAGTTTAAAGCAAGTATAATATTCTTCTATCAAGTTTGTATTCTATCAAATCCGGTAGCATTTGTCTAATTCCATATAGATGAATAATAAGTTTAAATTCTAGGAATGAGGAAGCTTTTTTCTTTACTGAGGATAGGAATTATATTACTCTGAAGCTAACAGATTTGATATTAGAGGTTGTTTGAAAAGGGGTAGGGATGTAGTCAATGAGTACTAAACGCCAAACAATAAGACTAGTAATGTTTATGTAAATCATAATCTCCGAGTTTTGAGGCAAATAGTCAGTCATCTTGGCTTAAGTGCCAACAACAACTATACCCTTCCTAGGTGCGCTCAACTACCCAATACTTTTTGAGGAGAATGAAACCCTTGAATTATTTGCTGAGACAGCACTATTTGCACAATTTGGAGCCTCAAAAAAAGACTGGTTTTTGATGAAAAAGATTGACACCCTTCCCCGCTGACATGGAGACGCCCAAAACCGCCCTCCGAAAATCTTAGATTCAGCTTTTTATTTGAGGAGCAAATTTTGATAGCCTACCTGGTGGTAATTCTGCTATTAGGGGTTTTTCCTTTTGAGGAGAGTAGTATTTTGTTTAAGGAATAATACCTTATATGTTCTGTTGGTAATATCTTGAATGATTACTTCAACTAAACCTTTAAACTGTGCATCAATGGGCAGTAATTTCATAAAATACTCTAGTATTTGTTTTCTATCTATTTTGAGCTGAGATTTTTTAGTGCCCGATAAATGGTTTTGAGGTAGCTTTCGTTCTTTTTGTGCTCAATAGTTGTGAGAAAATCTTCAAGGTGTTTTAGCTTTGAAAATGGGCTGTTGTTGTTCTCCTTTCAGAAGGTTGTTTTTGTCTTGTAATTCTTTGAGTTGTGTTGGAAAGCGCTCATACAGGTTCAGTTGTACCTCTACTTTTTGAGACAAAAGCTTGTCTTCAATGACCCTTGGGTTGATTGTTTGTAGAACCTGAGTCAATAATTTTTGGAGCTTCTAGGTGCTTGTCTCATATTTCATATTTGATCACCAACTGTATTCCACTGTCATTATTCTTTATCCTTTATTCTTTTTTGTGATTGGCCCAATACACTGCATCGCTCTTATGATGAGGGTAGTGATCAATCATCAACTAACTCATCATATTGAGTAGATACTTGATCATTACCATGTAAAATTATCAAAATGAAAATGATAAATAACTGATAACTACTCTAAACTTAGTTATTAAAGCTAACACTAAACTCAAATAAAATGTCTAACTTAATCCTATTTTGGCATCGGCGTGATTTACGAATTTCAGATAATGTCGGACTGACACAAGCATCTCAAGAAGGTCAAACCGTAGTAGGTATATTTTGTCTTGATGAAAATATTCTTAAACGAGACGATATTGCTTCTGCAAGAGTTACTTATATGATTGGTTGTTTACAGCATCTACAAAAACGCTATAAACAAATAGGAAGTCAACTTTTAATAATGTCCGGAAAACCTATAGAAGCTATACCAAAATTAGCAACTTTTTTGGAGGCTAAAGCTGTATATTGGAACCTGGATGTTGAACCTTATAGTAGGAAACGCGATCGCCAAGTGAAAGAAAACTTAGAAGCTGCAAATATTCAAGTAAAAACTTTTTGGGAGCAACTTCTTCATTCCCCAGAAGAAATATTTACTTCCACAAAAAAACCCTACTCTGTCTACACTCCTTTCTGGAAAAATTGGCAGGGGAAAAAAAAATCTAACCCGCTAAATACTCCCGTACTCAAAGGTTTAACTGAAGATCAGCTTCAATACACAAAAAAAATTGGAGTAATTGACTTGCCTACTGCTAAACAATTAGGATTTAATTGGGACAATAAACTAATTCTTGAACCAGGAGAAACAGCAGCATTAGAAAAACTAGAAAAATTTTCTAATGGGGCGATATCTTCATATCAAGAACAACGAAACTTCCCCAGTCTTGATGGAACATCTCAACTAAGTGTCGCTCTAAAATTTGGTACTATTGGTATTCGTACTGTTTGGGCAAAAACTCAAGAATTAATTGAAAATTGCTATAGTAGTGAAGTATTTGAAAATATAGAAACCTGGCAAAAAGAAATAGCATGGCGGGAATTTTATCAATATGTTATGTACCATTATCCCGAATTAGAAACAGGTCCCTACCGAGAACATTGGAAAAATTTTCCTTGGAAAAATAATAAAGCACATTTTCAAGCTTGGTGCGAAGGAAATACGGGTTATCCTATTGTTGATGCTGCTATGCGTCAGTTAAATGAAACAGGTTGGATGCACAACCGTTGCCGGATGATAGTTGCCAGTTTTTTAACCAAAGATTTAATTATTAACTGGCAGTGGGGCGAAAAATATTTTATGCAGAATTTAATAGATGGAGACCTTTGTGCTAATAATGGTGGTTGGCAATGGAGTGCTTCCAGTGGAATGGACCCAAAACCCTTGAGAATATTTAATCCTGTATCTCAGACACAAAAATATGACCCAGAAGGGGAATATATTCGACAGTGGGTTTGTGAATTGCGGAGTGTAGATACTCAATATTTAGTTACGGGTAAAATTCCAGCGGAAGAAAGAGAGGCTATAGGTTATCCTCTACCTATTGTTGACCATAAAAAACAACAACAACTATTCAAGGATCTTTACCGAGAACAGAAAAATTGATTTTTTAGATTAGAAGGTTGAAGTTAATATAAACTCAAATTAATTATAACACAAAAACGTCAAGCTTGTAACAACTCATAGTCCCATTATAAGTATAAAATGGCAGAGCTGCTGCCACTGAAACAAAAAAAAAGGGGGCGTTTTCTTTTAGCCCCTTAAAAATCAAAATCATGACAGTCTTATGAATATTAACACAATTTTATAGTTAAGTGCGTTGACTCTTCCATATCATTAGTGATAATATTTGCTAACAATGTAAAGCAAGATAAACTTGCTGAGGGGATATCTCCCAATGTCTACAAGAAAACCTGTAGACGCTTTTAAACAGTTACGTCGCCTTGGTTATCAGCTAAACAGAAGTTTTAATTATTTAACCATGCTAGAGGTAACCTATCAAGATAGCGGTTACTTAGCGGCCTGGTTTAACACCACAAACTACTCTGTTTATTAGACTATAACATAATCTATATAACTTTATTAGTATAACTATGTTAATATATATAAACTTCAATTTTAGTAAATTAACAATAGTTAATCAATCTTTTAGTTCACTTAACAATTTTTATTAGTAGATGGACTCACCCATTTTGTGGGGATGGGTTGAACTTGCCTGTTGCCTCTATTTTTTTGTCTCTGACTACCTAGGTGATACTCATTTTAACCTACAATTAAAATAACATATGTTTTATAAAAAAACAACTAAAAAGTCATCCGATGGGCGGGGGAGGTAATAGCAACCCAATTTTTTTGTAATTTAAGTGAAGGGGAATATGTCATTGATTTGTTTTGCATTTGGCTAGGCATTCAACTTTATATATAGTTCGTTCCATAACTTGCTTGAATATCATAAACACTAAATAGCCATTTTTAAGGTCTGTTCAATATTTAGCATTCAAATTCGCCAATTTCTTCTTAATTTCTTTTACCTTATTTCCCAACAACTTTAATATCTCTACCCACTCCCCTACTTTCCCATTTCTCTATAGGGGTAGATCTCCTACTCTTGAAAAAGACAAAGAAGACTAAACCCTAAGTATTAGCTACGGTTTCCATCAAAATTTTATGGCAGGCAAGTTCAGGAAAATTCTCAGTAGAACGACGCTGAATATACTTACCATCTGGTTGTAGATCCCAAGCTTGTCGGTTGTCAGATAACAGAATGCCCATAATTTCTTGCAACTCTTTTGTGATTTCAGAGTCTTCCACAGGTATAATAGCCTCTATCCGACGATCGAGATTACGAGGCATCCAATCAGCAGAACCAATATACACCTCCTCTTTACCTTTATTATAGAAGTAGAAAACCCGAGAGTGTTCTAAATAACGCCCAATAATACTCACCACCTTAATATTATCACTGATACCTTTTAAACCCGGACGCAAACAACAAATACCACGGACAATCAAATCAATTTTCACCCCTACTTGGGACGCTTTATACAAAGAAGTAATAATTTTAGGATCTACCAAAGAGTTCATCTGGGCAACTATACGACCTGTATCTCCATTTTGGCAATTTTCAATTTCCCGACGAATCAGTTTCATAAAGCGATCGCGCATATTTACAGGTGCCACCAACAATTTCCGGTAAGACTGCTGACGAGAATATCCCGTCAAGAAATTAAACAAATCTGCCAAATCTGCTCCTAATTCTGGTCGACAACTCAACAAACCCAAATCAGTATAAATTTTAGCAGTCTTGGGATTATAGTTACCAGTGCCAATATGAACATAGCGACGGATATGACCTTCTTCCTGACGGACCACCATCACAATTTTAGTATGAGTCTTCAGACCTGCTAAACCATAAACCACATGAACACCATATTGTTCTAACTTCCGCGCCCATTGAATATTATTTTCTTCATCAAATCTTGCCTTCAATTCCACCAATACTGCAACTTGTTTATCGTTTTCAGCTGCAGCAATTAAAGCATTAACAATAGGTGAATTTCCAGAAGTCCGATAAAGAGTCATCTTAATCGCCAATACATTAGGATCGTGTGCTGCTTGACTAATGAAACCTTGTACCGTACTTGCAAAAGAATGATATGGATGATGTAACAATAAGTCTTTCTGGCGAATCACTTCAAAAAAATCAATTTTGTTATTCTCATTCAGGTCAGGAATTCTGAGCTCATCACCATAATGTCGCAACCTTGGTGGCATAGTAGATGTCCAAGTTGGATCTTTAAGATGAGGCAACGGCAACCCTAAAAATGACATTAAATCTTTTAAATCAAGTAATCCATCTACTGTGTAAACGTCTTTTTCTGATAACTCCAAGTTGTCCATTAATGTCTTTTTTAATTTACTTGGCATTGTTGGATTAATTTCCATTCTAACTACGGTACCACCTATACGCTGTTTTCTGAGTTCTTTCTCAATCACTAAGAGCAAGTCATCTCCCTCATCTTCTTGCACTGCCAAGTCAGCATCACGAGTAATCCGAAATACGTGATACTCCTGAATATCCATACCAGGAAACAGAGCTCCCAAATTGTGAGCAATGACTTGTTCGAGAGGAACTCCTGTCCAATTTAGAGTTTTAGCCTTTTGTTCTATTTGTAATTTTTCTGGTAAGCACAAAAAGCGAGGTAATATTTTGGGAACTTTAATTCTGGCTAATAAATCTTCTTGAGTATCTGGATTTTTCAGCATTACTGCTAAGTTAAAACTGAGATTAGATAAATAAGGAAAAGGATGACTAGCATCAATAGCTAGAGGAGTAAGTACGGGAAATATGTGTTCTTCAAAATAGTTTCTTAGATATGTTTTTTCTTCTCTATCTAAGTCTATATAATTTAGGATATCAATACCATTTTTTCTTAACTCTGGTCGTAAGTTTTGCTCAAAGAATTGGTGTTGTAAAGAAACCATTGGTAATAGTATTTGATTAATCTCATCTAGTTGTTCTTGAGGAGTACGACCGTCTGGAGTTAACTTATGCACTTCAGCTTCTATTTGTTTTTTAAGAACTGCTACCCTAACCATAAAATATTCATCTAAGTTAGAACTAAAAATTCCTAAAAATTTTAAACGTTCTAATAGGGGAGTACGGGGGTCTAAACCTTCAGATAAAACCCTACGGTTAAACTCTAACCAACTCAATTCTCTATTAAAGTAGTATTGTGGATTACTAAGTTTTTTTTCGATAGGAGTTTCTACTGTATTCTTTTTGTTTTTGGACATAATTATAATATGGATTTAAATTTATATTGATTGTAAGCTAGTCTTTATTACTTGTAAAGTATATTTTTTTTCTATGAATTGGTTGTGTAATTAATTATAAGTTATCTACTTATCACTTATTAGTACTGACCTTGCTTAGTCCGAGAATTAAATATTTATGGTAAGTATTTTTTTGACTCCCTTAAAAGGGGCAAGAGGCCTAATTTTTTGATTAAAGATTACTTTATTAGTAGATCACAAGGTAGGTCTTTTACATGTCATGTCTCACAGGGAGTTATCGTTTTTTATATTCCTAACCTAAAAACTGCTATAACTATAAGATAAAAAAAATCGTAGAGTTAATAGACATAAATCACCTGATTACCCTATATTTTATCTGCTTTTTTAGTTGAGTATATTCCACTTTATTTAGCATTTTTTACAAATAGGTATTATCCTTAATACGATTCATTTTTTATTAATAATTAGATAATAAATTCTTAGTTATCTTGTTTTAATTTGTTAAAATAATTCACAATAAAATCTAATTATTAGATAATTTTCTTATTATATAAGAGTACAAAACATAGATTTTAACTATATTAATTACTGCCAATATTTACTTAGTTATTAAACAAACTATACCATCACAAATTTACAAACACTCTCTTCGTAAGAATTCAGGTATGAGATGTGGAAATAAGAGAAATACCCGATAATTTTTTGTAATTAAAGGTAATTGCCACTAGAGACGGCTCAAAGAAATTAATCAGTAATTACGAAAAAACACTATATATAGCCTATACTAATCTATGGGATCAGACTAGATATTGTAGCGATCGCTTCCAGTTTTCTCTTGATAAGATATTCCTAAAAAACAGTTTTTTTATACTTCATTTATCAACTCTAAAATTCAAAGTATTTTGGATTTTATTACTGAATATTTAATTTCATTTATTAAATAATTTGATAATAATTAATTTTTGATTTTGTCAATAGTTTTCCCCATTGTCCTACATTGAATTTTTAAATAATTCCCAACTACCATGGCAGAAGCAATATGTTTTTTTTAAATTCTGGCTCTATGATATTGGCATTTCTCAAGTCTTGTTAATTGCTTAATTTACCTGTGACACTATTCTATTTTTCATATAGTTTGTAACTAAAATCCTACATCATCTTTCAAGAATTGCTTCAAGTCATTAGTCACTAGATATTCTGCTGAAGTTTGTGGAAACAGTATCCCAGAAAAACCTGATATTTTTTATCTCTATAAAAACCTTTAATATTAATAAATTTTCCTGATACTAATTCAAAATTACTCTATCTTAATTTTTCTAGTTTTTTATACTTTTCTACACCTCCTGTATCGTCTAATAAACAATTTATTTTTAATGGAAAGTAGTATATTTTCTATCATTATTTATTAAAACCATTAGCTTTTTGGTTGCATACTAGCTATCCATTAATACTTTTTTTACTGGTATTTTTTTGTTGTCAACCACATCAATTATCATTCCTTTTACGTGATTTAATTTACTCCTATCATCGCTTTCTAGGTCAGAAATACGATCATCTATTATCCATAATTATTATATTTTTGGATAAAAATATAAGCAATTAACTACTCCTATTCCACGAACTACTATATGCTCATTTCCATTATAATGACGTCGGAAAAGTTCAATTATTCGGGAATGTTTTTTAGTTATCACTGTATCGTCAAAAACTAAATATATATCCCTAGTAGTTTCAATTTATTCTTTGACATTATCCCAGAAAACTTCAGTCCCTAATTAAAAAAAAATTAATTGAAAATTAATCCGATCATGACTGACTTTTTGAAGATAAGTCGCCAGATTTATAATAGTATAATTTTTTCTAACTACTTATTAAATACTCACAATATTGTATGTAATCAAATTCTATGCAAAAATCCTTGATAAAACCTTTTTTTATATACTATAATGGTTAATAATATAGATAAACTTGACTCAATTTTTTCAGTAATTTCAATGTGAAAGTTGATAATGCGATCATCCTCCGGACGGTGCGACTCACCATCACTACCTTCATGCAATAAAGTCTGAGGATAGTATAATATAGCTTTATGGCACTGCTCAAATTTACTAACTAAGTACAGACATATCATAATTCTTATCTACTATATATATATAGAGTCTTTACGTAAGTCCTGGTTATTTTGACGCTTCCATGCTCTTAGTTGAAAATTTAGATCGGAGTTCCTTTCTCCTGTATTTCCTCCTGTAGGTAATCTAATAATTAATTCTACTGTTGCAGTTGTTTCAAATCTTAAATCATTATTTTCATAGACACTGTTTGCAACCATTGTAATTGGGTAAGATAGATTTTTAATTCTAACCTAGCTGGTCAATAAATTGTCAATGTTTCCATGACTTTGCCTCCTTTAACATTCTTATGGTAATCTTAGATAATAGATTGTAGCTTAATGATTAAATATTTCTGGTATTGTGAGGAGTAAGCTGATGGTAAGTCAATTTAAAAAAAACCTGTCAAGATTAAAATCTCAATTAAAACTTATTAGCTTAGTGGGAACAGTAATAATTAATTTCAGTTTTCCAGTGCCAGCTTTTGGTGCTTTTTTAACAAACTGGTTTTTTGACCCAGATAATAATCAACTTCAGTTTACTCTCCCAGCAGGTACAACTCCTACTTATTCTGTTGAAAGCAAACCTACTCGTCTAGTTGTCTATATTGAAGATACTAAAGTTAGTGTAAATGTGACTGAATTATATCCAGCAGGGTTAGTGCGTAGAGTTAGTCTCTCTCAAGAGAGAATGCAACAAGCAAAAGTTATTATAGACTTTGCTCCGGAAGTAGCTATATCTGCTAAAAAAGTCAAATTAGAACAGGTCGAAGCGCCAGAAAATAGTTGGAAGTTACGTTTACTTGTAGGTAAGGAAAAAACCTCAACTCCAAGAGAAACAAAAGTTTTAAATGGAGATGCTGTTACACTAACAACAAAATCTACAGAAACCACAGAACTAGAAGTAGATTCTTTTACACCAACAACAACATCTATAGAAACCACAAAAATAGAAAATTATGAATCTACCAAAGCAGAAGAGGATCAAGCTTTCACTCCACCCAAGCAAAACAGAGTAAGCTTTCAACAGAGAGCTCCCAAAGTAGAATTTCCTCTACCCAACCCCGCACTTTTGGCAGAGCCTTCTATTCCATTCTTAGTTATTCCCACGGAAAAACGAGATGGTGTCATATTTCCATTAATAGACACTTCGCGTGCTCAACAGTCTCCTACTGCATCCTCTGAAATTTCGGAATTACCACCACTCCAAGGGATAGAAATTGAAAATGCTTTTGTTCCACCTCCCCTAGACCCTGAAACTGTAGAAGAACTAAACGATAGAACTACTAAATCAGTTGATGTAATTTCCTTTGGAGAACCATTGCCTGGAACTTCAGGCAAAAATCAGCTTGAAGATGATGCTTCTATCTTAATTGAAGCAGGAAAGATAATATCTCTAATTTACCCCACTAGCGAGCTTGAACTACCACAGGGAGTTGAAATACAGGAAGTTTTGCTTCTCCAAGAGGCCATAACTGATGAATCTGGTAGAATTATAGTACCAGCTAGAACACCTGTGGTCGGTAGTTTTAAGACCTTCAGTCACGGTAGTCAATTTATCGCCAGAGCTATATATTTCAATAATCGTTTAATCCCCTTTGATGCTCGATCTCAATTGCTCGAAGGAGACCTTGATTTTAATGAAAAAGTTTTAGCAGGTAGTAGCACTGGTAGTGGTCTAGCATTATTACTGTTAACGGGTTCAGGTTTTGGTTTCTTGGCAGGAGCAGCTCTTGGAGCTGGTAGTGTTCTTTTTACTGCTCCTCATTCTGTCACCATTGAGCCGGGGCTTATTGTAGAAGTTCGTGTTGTTAAAGATTTACCCCGCTCTAGATTTTATGATACTAGTAGTTTTTAGGATCTGAAAAAAGGGCTGTGCTTTGGGAGGTAAAATCCTCTGGCTGCAGAGGTTGAGCTGATAATCAATAATTTTTACTTGAGCTGATAGCTGATAGATGAATTTCTGTACTTTAAAAGTTTGGCATTCTTCCCAGCTGTTAGGTACTGGGGTTTTATTGGAAGCCTAAGCTTAACCTCGGGTTGACCTTGGAGATCAACACCAGTAGCATTACTATAATTAGATAGTTAATTAGGAAAACAGAACGAGTGGAAAATTTGCAGTTTGAGCTGAAGATGAGTTTTTTTTTGGGAATAAAACGGTTTTGTTATCACAGGCCACTACTTTTGTTTAGCCATCTTTAGTGCCTGGCAACGAGTGGATAGGGATAGGCTTTTTTGTCTGAAGACTGCCCAACTGCAAATAATAAATTATATTATAACATATATATTCAAAAAAAAACAAATAGTCTTCCTATGGGTGAGTCGAGCTTTAAGCTCAATTTTTAGGTAAGAATGGTATATCAGCTAGAAATTATTATTTTCAGGTGGAGCAAACCCGGGCCCCATATTTTTAAAGAATAGGTTTTGAGCGCTGTCATTTTGATAAATGCAATCAATCTCTGGTTCATCGTTAATATTTCCTGTATACCCAAAGGTATTCATCCGGTTTTTACAGTCACGCACTTGCTCATTGTTGACTAATTTTCTTTGTTGTAGAATTTCCCAGTTACTTCTGCGGATGACACATCCTGGTTTCAAACCAGGCTGAGATACATATACATTAAAAGGATTTAAAGTCAAGAAAACGCGCATATTCATTACCATTGCGCTAGCTCCAAACTGTACACAAATTTCGGGGTTAGGTACGCTGCGATCTATAAATTCACTAGAGGCCATATTTTGTGGGGTAAAATTAGCAGTGGAGCTAAAGGCGATGCCAATGCCAATACCCAAAACAAATACTCCGCCTAAAATTGCCAGAGTAGCATAATTAAATCTGGATACTTGGCTGGTGGTTTGATTTGTACGTTTCATATATATCGAAGTGTTATTATATTTGAAATTATCTGAGCAGAGCAACTATTGGGCCATTAATAATGGGAAAAGCTAGATGTATGTTTTTTCTAACATACAGCAAATTCCAAGTATATGTGTATGAAGTATAGTTAAACTAAGCCAGGTAAGTTACCCTACCCGACTCGTCTTCAGAACCGGACGTGAGGCTTTCACCTCATCCGGCTCCTCTCTTAAACGTCCTTTTTTTCATAGGTACATCCCTGTTTTTAGAATCAACATATCATTTACCCATAGGTATTCATCAGGTAAGTCCTGTAACTTAGGTTTTGTGTATGTTTTATTATCTAAAGCAGTTTTAGTATCGTGGCAGTGTCGGTGTAGCAGTTGTTTATTTTTAACTGTGTTGTCACCACCTTCAGACCTTGGTTTTATATGGTCAATTTCCATAAGGTCGTTTGATCTGAAGGTTAATCCACAAAATGCGCATTTATTCTTTTGCCGTTTTAACAGCGTTGTTACTTCTTTCCTTATGCCTGGGTGTTTACCGATTCTACTGCTCCAATAAGTCCAATCGCCGTCATAAGGGGATTTATTGCCCTTTACCTTGACGTGTCTTTTTATAGCTACGTCTGCGTGTAGGTTAAGTACGTATTCGCCGTCATTAAGTAACCAGTTTCTGGTCTCTTTGCAGCGAGGGAAATACTTTTGTTTTACCCATTTGGCTGACTTGTTTGGATGCCGTCTACTTCCCCATCTCCATATCCTTTTCCACAGGAGGCAGTCTAATTTGCTGTATACCTCTTTACTGACTACAGTGGAGAAGTAGTTGGCCCATCCCCTGATTATCGGATTTAGTTTAGCTATTAAAGCTTTCGTAGGGGCGGTTTTGTGGCAATCACATATATCCGCCAACTTCCGATAATGAGTTTTAATACTCTTAGATGATGGCTTAATCAGTGTCTTAAATCCTTGTTTGGTTGTCTTGACTTTCCATTGCCTTATTGTAAATCCTAAAAAATTAAATCCGGGTTTGTTTCCTTCATATTCTTCCAGGGTGTGGGCAATTTTAGTCTTTTCTGGTTTTAGCTCTAATCCTACCTGGTTTAACCATTCCTGTATTAAGGTTTTTGCTTGTATTAATACTTTGATGTCTTTGTGTAGGATTACAAAATCATCTGCGTATCTTATTAAGGATAATGCCTGTATGTTGTCATGCTTTCTCCCTGGAAGGGTTTTGGCAAATTCTTCTAAACATTTTTCCATACCGTGTAGGGCGATGTTTGCTCTTTCAGGGTGAGATAACCCCTCCCTGTGGCGTACCTTCCACAGTGTTTGAGAATTGTTTGTTGTCACACACTCCAGATTTTAACCATTGTTTGATTAATCGTCTGTATGGAGATTTTCCTATTTTTCTCAACAGTGCACCATGGTTAATTTGGTCAAAACATTTGGATATGTCAGCATCTAAAACATATTTTGATTTTTTGTTGATGCTTTTATAGATGGCTTCAATGGCATCATGTGCTGACCGACCTGGTCTAAAACCATAGCTATTAGGCTCAAAAAGTGCCTCCCATTCTGGTTCCATACCTAACTTTACCAGTGCTTGAAGGGCCCTATCATACATGGTAGGTATGCCTAGTGGACGTTTTTCTTCTCTACCTGGTTTTGGTATCCAGACTCTACGGGTTGGGCTTGCTTTAAGATATCGTGACCTTAACATTTCTACCAAGTTAAATCTTTGCATTGGGGGAAGACTTTTTATACCGTCTATACCCGCTGTTTTCTTTCCCTGGTTGTCTTGCGTCACACGCCTAACAGCTAGCAACCTAGCATAATAACTTTTGGTCAGAAGTTTTTGATACTTACGCATTTTGCGGATTTCGCCACGGCTGGATGCTCTGTAAATTAACTTTTGCAACTTAAATACATATTTTTCTACCTTTTTCCAGTTAATGTCTTTCCATTTAAGGTTAGGATTGACACTACATAGGTCTGGTATATCGTTTGTATCCCATGCTACGCTTAAAAATGGCTCAGGATTTTCTAAGTTTCTTTTTAGGGTTTTAGCTTTGTTCATAGCTAGTCATTACTTTACATTACGTCTAACAGTGAGTACGTCTGCATCTGCAATGCTTCTTACTCAATCCTACTCTCCTTAAAACCTACAACTTCTGTGTAGATTGACCTTGAATGGCTTCCTAAGTTTTCGACCTATTTACTTAGGTGTTTTTAAAGAGGTTTCCTCGTTCCCTTATTCCTTTATTGCGATTGATTTAGTGGGGTAAATTCTCCCGGGGGTTATGACATGGTTGTTGACATAAACTATACTATATTTATGTCCATTGGCCCCTGACCTTCGTCCAACATCCCATAGCTACCTTCGGAATGGTCCTTAATAACGAGAGTTTGATTACCTTCCTATTTGTCCACTTGTCAACCTTTGCTCGCGGTATCGTTCCTCGGTAACTGGTATTTTCCCGCTTTTAAACCAGCTTCAGGGATTGATGTTCAATCGCTACCCTGTGGTCTACGCTGTCAACCTAACAACAAGGTGGATGGAATTACACCATCAAGGTAATAAGAGTTATTCACAAGTCGAGGTTTTCCTCATGTGGTGACTTGGAATGGTCATTTATACACAGTTTCCTGGTTTTAGTGACCAACGAGTCGCACAGTATATATGAAGTCCTCACCCCAGCAGGGGGGACTTCAATTCTACAACTATAAATTTTAGCAAGGAAATTATTAGTCTTGATTATGTATAAAGAAGTACAAAAGATATGGACTTTGATTATATTGTGACAACTTTCAAGTTAGGAGTTTTTTATGTCAAAAGTATTAATAAAAAAGTCAGATGACAAAAGAATCTGATTTTTTATTGATTTTTTTAGTTTAATGTTAAGTTTTATGTTATGTGTATACTATAACGTAATATTTAATTTATTTAAGTAAGCAGGATAGAATAGTGTCTATAGAGACTATAGAAAAACCTACCACTTCCACAGTCCGTAAAACTGCACCCCATTATCGTGTTTTACTCCATAATGATGATTTTAACAGCATGGAGTATGTGGTGCAAACTTTGATGAAAACAGTACCAAGCTTGACTCAACCCCAAGCTGTTAACATAATGATGGAAGCTCACTCAAATGGTATTGCATTGGTAATTATCTGTGCTTTAGAACCTGCAGAGTTCTACTGCGAAAATTTGAAAAACCATGGACTAACCAGCACCATAGAACCTGATGAGTAA

Protein sequences of DBSCAN-SWA_3

>NC_008312|1661571:1764252|1696855_1697746_+|WP_011610834.1|DBSCAN-SWA
MSSTITPSQENISQLSDAKTTTFTSGSLVGDFFQETLALTRRLFIQLKRRPSTLIAGIIQPLMWLILFGALFQNVPQGLFGESQNYGQFLGAGIIVFTAFAGALNAGLPVMFDREFGFLNRLLVAPLTSRFSIVLASATFIVTLSLLQSAIIIGAGAFLGAGLPNILGLATIALIILMLVLGVTGLSLGLAFALPGHIELLAVIFVTNLPLLFASTALAPLSFMPSWLQVVASLNPLSYAIEPIRYLYLHHNFSFGSVVMEAPFGDISFGIALLVLLVFDIVTLVAIQPLLRRRFA
>NC_008312|1661571:1764252|1736813_1737596_-|WP_052845750.1|DBSCAN-SWA
MPEESYKNNEVAFLGEVADKLSLKDNTRLVFIERFKINNDDLNNAALADVLLTNLRHNNTMRDALRRIFKKLEVEGCHFNDATRDKVNIARQWLREVLYPWYQLKNMATSTNKMGPVLQGMSTMDMYTVDPHYPKTVPLDSEIKFEVRLERRGYLTLLERGTSGEFYCLSPSFLGALPIFDAGVVSLPMEGAPVDYFRLDGKPGVEEIIAGISQERPRLSWLPQGDQPPLLLEGKHLQEFLTYFQAESDSTLWYMFYDVV
>NC_008312|1661571:1764252|1763964_1764252_+|WP_011610869.1|protease|DBSCAN-SWA
MSIETIEKPTTSTVRKTAPHYRVLLHNDDFNSMEYVVQTLMKTVPSLTQPQAVNIMMEAHSNGIALVIICALEPAEFYCENLKNHGLTSTIEPDE
>NC_008312|1661571:1764252|1712153_1715477_-|WP_011610844.1|DBSCAN-SWA
MQKSPNIDAEIVAGLNDIQAFINLIQTEFLFDDVSLNTIDIFTLRQASCTQDQNNFTFTLGVTIAIEQDEGQGLTTKELSGSLVIEIKTDDNGNNYKGVYGGSLSIPIKPTGALVFRLDYQTKTESGKNTKLVVGSLDANANQNLGNVNLSNLVSEICPSLTDLFPDELLNFSLGSDVIFVINSTNNGQRNQNKMLFSIGFDAEIALSDIPLAGSLLPPNSLEGEFAFEFLVSFQKFTQKEVKTINSLLEELGTKLLIKPPCSSINNLERGASIGAHFKIAQFVQAWLLPLVKTPPTAAGGSRSLSTTTNNVSGKVSSDEVITPTDNGAWLNTQKLFRRLYFQKVGLVYKKIAQFVQAWLLPLVKTPPTAAGGSRSLTTTTNNDSGNVSSDGVITLADNGVWLNIQKSFGPLYFDKVGLVYTKGEMRLTPKFIIEVSRFTLALNGLYISSGLTAFKPHFNLDGFGLELKTRSLEMGGAFLVAHGAEGQNNYDEYLGIVTVSFQKKVGPALALSAIGSFTDYQNSDQFALFLYLAADYPFGGPPFFFVTGISGGFGYNHDLIIPPLEDIKKFPLVTEALKGPQKIDPDQTGEIITEKLEALNKYIPPSIGSGFGALGLKFTGCKIVDGFGLITLGISQNEFEINLLGIATMMLPTKLKDNYEPIAMAELAIAGRFNPMEGVILIQGQLTENSYIFSRNCRLTGGFAYGLWFLGDFVFTQGGYHPRFQVPDYYPNVPRLGLNWQIDSHSHITAQAYFAICGHGIMAGGLMDIRYQLGSVWAHFEAGLDLLLGWAPYHYDVNVYCSVRVGVGALSVGLGMGVHIWGPDFGGKLELRVFVCKVTIKIGDQSSIYPVPIKWDEFEDTFLPEPENVCSLTSINGLVKQVLEPTRKEEQKEVWIINPTVFEMSTDSLVPTKQAFVGEQKKEINTDTNFGINSMGVDNNELDTTHKVTICKDSRERAEDKFKFEPITKLASTSTWGEPNMVNGHIKPPEVNGKQFIENVFFGFRILPAELPKAGKTHEIGVEHLQYETEKVEDAYLWESCTPFVPNPNLDEENKRNKIMQTVGSNEQRNKILAALGWDVYQVDMNEDEAEAIANSFVFAPLIKLT
>NC_008312|1661571:1764252|1680862_1681228_-|WP_011610826.1|DBSCAN-SWA
MNNPKRGEVWLVKLDPTRGQEIKKTRPAIVISSNIFRSVSVKIIVPIAKWQSKFKNRLFMISIPKTDENGLDNDSAGNVLQVRSIANERFVRCLGRVSNSILEELLAGLIICIDYEYDSLI
>NC_008312|1661571:1764252|1694035_1695550_-|WP_011610832.1|DBSCAN-SWA
MGYDFDAIIIGSGAGGGTIAHTLAKAGKQVLIVERGPRFSDVEAFQDEQRMLINKEAFDDRQIEVNGRNAQLHIAGILGGGTSLYGGVLMRPSPYDFHPGKFYDQWLPRHLWDWPITYDDMAPYFEQAETLFHVAGDRPYKMPNVGTPSKGYPATVPPLEPINQQLEKGIKDAGLMPFHLPFGIDFKSCLRCSKCPGFYCPNEARASTVVRTIDKATLDYHLQVQTFTEADRLVTNSHQKVTGIRLRCRKTNKVQELTAKLYILSAGALGSPIILMKSGLTGRSGQVGRNYMYHCGALVAGLFKQETGGADKFIKQLGFTDLYLGNKEFTHKLGLAQTVPIPGLLSLQQNFPIPIPKTIAEFLLKRMLAITGIVEDLPQQENRIELGKDGKIRLFHKFHPYDVYRSQYYKSKLKQVFRLAGSILSFGATGDKDDIHTSHQVGTTRFGTDPNTSVLNKDCRLHEHENVFVVDGGFMPNALGVSPALTIAANALRVADTILQKAII
>NC_008312|1661571:1764252|1699321_1699525_-|WP_155994315.1|DBSCAN-SWA
MTGYFMLWKMLLYSNAETSATVIVYNSNNGKLFYNANDIEAEFGTGGQFINLTNIPSISKDDFLMRK
>NC_008312|1661571:1764252|1672963_1674496_+|WP_011610823.1|DBSCAN-SWA
MTETIQRKMKLNSFDKFKAEKDGLAVKTEIEHFAKIGWEAIDKTDRNHRLKWLGVFFRPVTPGKFMLRMRMPNGMLSSQQMRVLAGIVQRYGDDGNADITTRQNLQLRGIAIEDIPDIFNRLEKVGLTSVQSGMDNVRNITGSPVAGIDATELYDTRELIKQVQDMITDNNKGNFEFTNLPRKFNIAIAGCRDNSVHAEINDIAFIPAYKNDKFGFNVLVGGFFSAKRCEAAIPLNAWVEPNQVIALCRAILEVYRDYGLRENRQKSRLMWLIDEWGLTKFRSQVEKQIGLTLETEALKDEILWEKRDHIGIYKQKQPGLNYIGLNIPVGRLYAVDMFDLARLAEVYGNGEIRLTVEQNVIIPNVPDSRLETFRSEPLLKKFSFEPQPLTRAVVSCTGSQFCNFALIETKNRALAIAKELETELSIPKPVRIHWTGCPNSCGQPQVADIGLMGTKVRKNGKMVDGVNLYMGGKVGKDAQLGSCVQKSIPCEDLKPILRSLLIKNFAAQPK
>NC_008312|1661571:1764252|1699958_1700078_-|WP_081432527.1|DBSCAN-SWA
MHLYVEGIQQKGKYLSANGKILIYACEIASGKEGREFVR
>NC_008312|1661571:1764252|1715630_1719581_-|WP_011610845.1|DBSCAN-SWA
MSKTLLVPIHTDALCLKEDKQAVRAMVDYTLLPYKYKEHTYNSGSENLSKTALGPLFNHEFTLKKGIHLHWSLPDALTNGQHDSNGTTFPVVPNRWLIVRKGGETEEKTWVIESDYLYPELDPNDSSSSPPNAINILIQPPDLATVDPKKPDTYQYQRYRYMGKCWELSQWPEEGGENPEYAEELTAMGNQATIPIFDEVKATFAAFYPNCYSVFGFHDPDFETDTPPKDLQYDVIGWYSDAEDDCLKQFVEANSCTTAEEFLQALQEQFYWTFEGVKDILHRTLYHSRITFTGAGNWPTLETPTLAIGNSDSEAISAYLAQEFNGDTNDSGKTVRKSIQDTLETLHLSERLESRKLDLDAKFREGRQERGFGAQNEGVLWLLMPRSSQLEQPNTKTSLDLLPDHLAQLLNELNALQEDYNQAWLDIGSLRDRLYTQWYYSITHKTSPTNFYQIFNKTSLIPLRTAIAKTGELEFTQDEKGNTTVTSKTLPFGILSWLNTYFSNYVDTMQLATNSSFNKWEDIQVEFKNCGVEISDSPIVSKIIDDQEWEIQDNGLTYPVKVEGGIFTIYIPPSEAQVAFNLVKKLNELSQAITTYNENSATQYQLRTFPTQSYWRGNDPVILLAGESTKSPLRFGQDGRLHDDDLLECIPLDFDITEILNNHQDLLNQINSLQPDESKESINFITWTQQPWNPFAFHWSVLNYPCRDIESSTVQDYNSNQILDNYELQKNAIDLKLRDGKESSFISNGNTYSGFSILTPSAGTELILRLSTYLNEQLLPNYYSKNNISEKDQTSNYLDDNLDEITNWYQEENQLEIQEQQAADPTFIALWAYRKMKTLDCQAQMLGGFNDTLLLGQPTLQLQVDDPLDTDNIGQLVTEQVRWSLGNRLQHKILSGDIFNPIRSGGFSVKKLWLIDTFGQYQEVVNDSNQNTKIVTTYQMTPADKNSVNYQAILPPRIAQSSRLNFHWLSADALQEVEYTKIPARTPVCGWIVPNNLDSNLAIYDNQGRSLGSIDLLGNWRNAPGVKLSRDHNGYPLLGNDHLQKLAHHLLEQGKDFQQQFLSTVDNALETIDPESFAQNTGLALLVGRPMAIVRATFSLEVKGLPACDPTVLVQEENEFPSYGFTGVQVPIRLGDYQQLNDGLVGYWKEIPKANGIEGDYEYENNIFYATQSNLVDSNNIITDSEGIVHFLQNVDAEPQSVTMLIDPRGLVHASCGVLPNQELRLPSEHYNQALEKMEVNFLSTPILSNSGELAMPLSPEANATWSWVSLTKSENGEEWTERATIKPINTRATFTQMQEALEGWLQLSRANITDE
>NC_008312|1661571:1764252|1671147_1671966_-|WP_011610822.1|DBSCAN-SWA
MSNSIKKFREFEYNAWQKSVDQYDSSFASLTNQMIQPLLNAVNAKKGNKILDIATGPGYVATDAAKRECNVIGLDFSDGMLNKAKQLNPDLEFIQGGAEFLPFENEEFDAVVMNFGILHLAEPQKAINEAFRVLRYAGKFAFTAWDIMDKCIGMKLVYEVVKAHGNLEVSLPEGPPFFYFSEEQNCIYGLKNAGFSSPLVSKFSLAWELANADEWFDAFYKGAPRTGALLRSQAQENIADIKAAFHQISQPYVDKNTLILPMSALVASGTKM
>NC_008312|1661571:1764252|1701533_1703168_+|WP_011610838.1|DBSCAN-SWA
MNVQTVVTKPFRDQKPGTSGLRKKVPIFKEPHYLENFIQSIFDSLEGFSGQTFVLGGDGRYYNRQAIQIILKMAAANGVGRMLVGQGGILSTPAASCIIRKNQAFGGIILSASHNPGGPEEDFGVKYNISNGGPAPEKVTSAIYERSKVIDSYKILEAKSINLDQLGSEKLGEMTVEVIDSVADYADLMESLFDFGKLSQLLSSGKFRMCMDSLHAVTGPYAKNIFEQRLGAPLGTVKNGMPLEDFGGGHPDPNLVYAHDLVEIMFGDNAPDFGAASDGDGDRNMILGKNFFVTPSDSLAILAANAKLVPGYSSGLTGIARSMPTSAAADRVAEKMGLDCYETPTGWKFFGNLLDADKATLCGEESFGTGSNHVREKDGLWAVLFWLNILAARQESVEDIVKEHWKTYGRNYYSRHDYEGIESDKASTLMENLRSLLPSLPGKQYGQYEVKYADDFRYTDPIDGSVSQKQGIRIGFSDGSRMVFRLSGTGTQGATLRLYVESYEPDTTKQDQDTQIALSPLISLADEIAQIKNITGQEKPTVIT
>NC_008312|1661571:1764252|1683869_1687460_-|WP_044137191.1|DBSCAN-SWA
MNSQFLNRLHSPERPVIVFDGAMGTSLQVQNLTAEDFGGKEYEGCNEYLVHTKPDAVAKVHRDFLAAGADVIETDTFGGTKIVLAEYDLADQAYYLNKTAAELAKSAAAEYSTPEKPRFVAGSIGPGTKLPTLGHIDFATLKDSFTEQAEGLFDGGVDLFLVETCQDVLQIKAALNGIEEIFAKKGDRRPIMVSVTMESFGTMLVGSEINAALTILEPYSIDILGLNCATGPDLMKEHIRYLSENSPFIVSCIPNAGLPENIGGQAHYKLTPVELKMALMHFVEDLGVQVIGGCCGTRPDHIKALAEITETLKPKERKPNYIPAAASIYSSETYEQDNSFLIVGERLNASGSKKCRTLLNDEDWDGLVALAKSQVKEGAQILDVNVDYVGRDGVRDMHELASRLVTNVNLPLMLDSTEWEKMEAGLKVAGGKCLLNSTNYEDGEPRFYQVLELAKKYGAGVVVGTIDEDGMARTADKKFEIAKRAYDAAIEYGIPARELFFDTLALPISTGIEEDRENGKATIEAIKRIREELPGCHIMLGVSNVSFGLNPAARQVLNSVFLHESMAVGLDGAIVSANKILPLAKIEPKHQDICRKLIYDQRQFEGDICVYDPLTELTKMFEGKTTKKDRSATENLPIEERLKQHIIDGERIGLEDALRKALETYPPLDIINVFLLNGMKVVGELFGSGQMQLPFVLQSAQTMKAAVAYLQPYMEKEESGDNSKGTFLIATVKGDVHDIGKNLVDIILSNNGYRVINLGIKQPVDNIITAYREHNVDCIAMSGLLVKSTAFMKDNLETFNQEGITVPVILGGAALTPKFVHEDCQNTYKGKVVYGKDAFSDLNFMDKLMPAKAEKQWDDIQGFLNELAEENGNGNGNGNGNGNGNGNGNGKVATSVKSEDQEESQTAAPVDTRRSDDVPVDIERPTPPFWGTKLLQPEDMPFEELFWYLDLQALIAGQWQFRKPKDQSREEYDEFLAEKVYPILETWKSRVITEKLLHPQAIYGYFPCQAEGNTLLIYDSEEMSQTGKATKVVNSFEFPRQKSGRRLCITDFFAPKESGVIDVFPMHAVTVGEIATEFAQKLFADNQYTDYLYFHGMAVQTAEAMAEWLHARIRRELGFGSKDADNIKDILRQRYQGSRYSFGYPACPNMQDQFKQLDLLETKRIDMYMDESEQLYPEQSTTAIVTYHSAAKYFSA
>NC_008312|1661571:1764252|1707586_1709560_-|WP_011610842.1|DBSCAN-SWA
MPTTEKGKVQFIQFHQPALESGTYDLKVEQTIKAGDKIDNNGNGKTYSRELTFVVQGERFGPLSPNDIYAVFPPPESLGEHSNVLPHITFKRSTLPWERYPGQTDDNLPWLILLLFRESDFDGNEEDKPKPKNVTLSELITENSPNIKYPTMVLELGQTPNQQVTVIDVKKKYLQDILPTYEDLSYTAHVRRRLLASASEENLKLLEKEYSTIICNRLPEPSGKSTVYLVSIEGRYSNNKFYFMDAKEDDLIRFVSLASWEFSCIDPEQSFTKLLQRLNHAPSSPRLPKSDNEKAEEYLKKGYVTIPHSLRKGSKTYSWYSSPLGTAFNDKEQEIYEFPMKASDQLLRYDSEIGMFDISYSAAWQLGRMLMLENQGLAVQLFKWKREVVQNIKRLQQQQTHLRLINSTSSKTKKIIPNPVKQWFQGLGLLQGVPFNYLVPDEGLLPPESIRFFCLDSVWIDCLQDGAFSVGRVTKGDLSDDKKIIELNNFLRQQNKTISGIIMRSQVVSGWPGLLVDGYDQVVSDLDSIDPTEANLLPLLRMETLAKDVLLCLFEGEIKTVDIHLQPESMHFGLDAPTEDSPEWSKNLRNSEGELMENSIPIPWKNEEKEVIDLQKFATQMKETLSSSDEDEFTSGQFGLQMIEGVQKVRLVFKESV
>NC_008312|1661571:1764252|1753133_1753292_+|WP_155994318.1|DBSCAN-SWA
MSTRKPVDAFKQLRRLGYQLNRSFNYLTMLEVTYQDSGYLAAWFNTTNYSVY
>NC_008312|1661571:1764252|1731394_1735918_-|WP_011610853.1|DBSCAN-SWA
MTEEQFQEQLKARLDLIDQLLTCSSGEEQAILHANSQLLDAAFVKTMELVAAKMVEDGEKNAKWLQGLANELAEMMEAKEKLDVQVMELYNAGKYDEAIPIAEQGVTLARQLWGESHAEVATNLNNLTLLYESQGRHSEAEPLYKQAIEIHKVALPANHPSLATNLNNLANLYRAQGRYSEAEPLYKQAIEIFKIALPANHPSLATNLNNLAGLYESQGRYSEAEPLYKQAIEIFKIALPANHPSLATNLNNLANLYRAQGRYSEAEPLYKQAIEIDNIALPANHPSLARDLNNLAELYRAQGRYSEAEPLYKQAIEIHKVALPANHPSLATNLNNLANLYRAQGRYSEAEPLYKQAIEIFKIALPANHPSLATNLNNLAGLYESQGRYSEAEPLFKKAIEIDNIALPANHPSLATDLNNLAGLYSSQGRYSEAEPLYKQAIEIDKIALPANHPDLATHLNNLAGLYKSQGRYSEAEPLYKQAIEIHKVALPANHPQRASGLNNLAGLYRAQGRYSEAEPLLKQAIEIYKVALPANHPFLATNLNNLAELYRAQGRYSEAEPLYKQAIEIDNIALPANHPELATNLNNLAELYRAQGRYSEAEPLYKQAIEVDKIALPANHPSLATNLNNLAELYRAQGRYSEAEPLYKQAIEVDKIALPANHPSLATHLNNLAVLYSAQGRYSEAEPLYKQAIEVDKIALPANHPSLATNLNNLAELYHAQGRYSEAEPLYKQAIEIHKVALPANHPSLATNLNNLAELYRAQGRYSEAEPLYKQAIEIHKVALPANHPQRASCLNNLALLYASQGRYSEALKLMLKASKIEDKTIQAIFASSSESDRLAHIKQEVRPNLETFLSLVYQHFPHSPEAKQAALNLVLKRKSLTATAMAAQNQAVFSGRYPQLQEIFPQWRRKCDQLLTLTYEVPRPEKRETHKQQLAQLQKECNELERKLTQQMPEIEIQQQMGDIRAVASELSEGEKLLEFVQFDVYDVQEKSWGKARYLAFVLAGGKPSEVEMIDLGEAENIDRLISTYRNSVIKWPLPQQMNMWNNKPNSTETETPTKHYIYDSQPGKELREAVFDKLRDKLTGCSHLVLAPDGDLNLVPFQILPEDDGKTTLQDEYNISYVSVGRELLRRRIKTKPTANPPLIMADPNFDWPQNAPDMAQQKESPAVSGLNVQPMLGTLAGITFPRVKATADLAKTIGQQLGVKPFLGNEATADRLLKCQSPKQLIVATHGYYSQRKDKYLTLLKELLSSSQGKEVEILEKNYGLLDEEFLAFIERYRNSENRDNKIREKLRAIAPLVKQQLKTTPVKPPVNNMDFETFKPNRHQAKIENPMMGSAVAFTGANTWLSGGQLPPEFPTMAFAQDIAGLDLWETELVILIACESGLGDVQTGEGVFGLRRAFAVAGNQTLIMSLWSVPTLATMLLMEQFLDDSRSGMSAGAALRKAQKYIRNITVGELQKSKLGSDILGELNLGKNLKIESKPLAHPYFWGAWICQSVSELGIRF
>NC_008312|1661571:1764252|1747475_1748141_+|WP_011610860.1|DBSCAN-SWA
MSITCDLCFYNRNSEKNKFCEVCGSEIRLSTTLLKTQEKSIQEGEIQTAIQTDKNTVNQDKDINQNINNYFLKTPTYINKTTSQNPIIEADKKVNMTPKNAINSTLINSSIVKLIPKQIGAPIPEFIIDSNNAIIGKFNPEIGPVEIDLDGFYGDNTVSLTHAEIYFKNNQWQIKDMGSTNGIYIKHIGKTRFGYRINKPEILNSGDEIAIGKIRLLFIIS
>NC_008312|1661571:1764252|1726891_1727725_-|WP_044137193.1|DBSCAN-SWA
MNLLFCFDQNYQQHFGVAITSVLLNNLSSHFDVHIITNFMEEKLKQKLDTLSKNYKCSFHLYIINNLDKISKLKVSDHVSNATYYRLIMAEILPKHIDKVLYLDSDVVVISPLEELYNIDLENYFIAASGFSGTLVKSKGFNSGVMVVNLEKWRNEQISTKVIDFATKNRDKLPYHDQSALNRVIKQNYLIIDRKWNFQVDLSPRKIQKPDDNIALKNARIIHYIGSSKPWYFWISDQRKNIYELYLKKSLWSTSKLQMIFQQTVYFRKALQRKLKK
>NC_008312|1661571:1764252|1721595_1723065_+|WP_011610846.1|DBSCAN-SWA
MVTTPSFKPTYEQNTFKLSPTATTTTLPWNNTSLPTTPLFGTDGIRGKAGELLTAPMALQIGFWAGQVLPQYCQNPGPIIMGQDTRNSGNMLAMALSAGLTAAGLEVWNLGLCPTPCVAYITSISEAIGGVMISASHNPPEDNGIKFFGSDGTKLSSELQQKIESGIRGTANFPTNHSNWGQHYHRPELVKEYQASLHSPLTPGSLQGMKIVLDLAWGAAVHTAPEVFRGMGAEIICLHDQPNGDRINVNCGSTHLSHLQQAVIEHNANLGFAFDGDADRVLAIDSQGRSIDGDYILYFWGQSLSKARLLPNNLIVTTVMANLGFEHAWNKQGGKILRTKVGDQYVHAEMQRTGSMLGGEQSGHVLCPHYGITGDGLMTALHLATLVKNSGISLAELVDQSFKTYPQLLRNVRVEDRDRRANWKNCEPLVKTIEEAETALADLGRVLVRASGTEPVIRVMVEAINLELAKSWTENIVLAVQQHLLPTKD
>NC_008312|1661571:1764252|1728099_1729266_+|WP_011610850.1|DBSCAN-SWA
MKILIASHTYIVDLNREKLRALAKLEPGLEVRVVVPRRWNPKGVQSEIVETKFIDEGSFKVIPLSNYSQNNQALLTFGPELISLLRKFKPDIIQVEQGSKALTYAQFITFNKLLGLQAKNLFFTWWNLPYELKFPISYLESYNLRNTDGIVAGNKDGEKILRNKGYKGLIKVMPQLGVDESLFKPEPQVELRDSLGIKDDDFVVGFVGRFVQEKGLLTLTKSLAGLQEKNWKCLLLGRGELQATLWEIATALGIKERLIFVESVPHNYVQKYINLMNTLVLPSETTYKFKTLTSVGWKEQFGHVLIEAMACKVPVIGSDSGEIPNVIGDVGLVFPEGNIEELRNCLMQLMEQKELAESLGEKGYKKAMSQYTNKSLARQLLSFYQELL
>NC_008312|1661571:1764252|1757930_1758164_-|WP_044136443.1|DBSCAN-SWA
MICLYLVSKFEQCHKAILYYPQTLLHEGSDGESHRPEDDRIINFHIEITEKIESSLSILLTIIVYKKRFYQGFLHRI
>NC_008312|1661571:1764252|1730624_1730951_+|WP_011610852.1|transposase|DBSCAN-SWA
MHCPYCQSHKIVKNGHRNGKQSYLCRKCGRQFRENPCPIGYSSEVKEACLKMFLSGMGFRAIERATGISHNSVLNWVRRAKVNVSDRNSEASEAAQVDGLQIFVDPKK
>NC_008312|1661571:1764252|1661571_1662207_-|WP_011610817.1|tRNA|DBSCAN-SWA
MTNTEKKYGLAIHTTSPELGLAISNFDEYTRSQTWNLGRDLSNNLHQKLQEFILPQIWQDLSFITVAKGPGSFTGTRIGVVTARTLAQQLNIPLFAISTLATIAWSYKQKSHNLFLQMHAQRGQLFTAIYQVEEMGINPISGDTLMNPLVWEKMLVDWDNSYHLIQVKNSLGKYVVSLLELAHLEWQKGNRPHWSEALPFYGQSPVEKYPL
>NC_008312|1661571:1764252|1723361_1724966_+|WP_011610847.1|DBSCAN-SWA
MPKKQKSQKKLKKKGKPATPQISKKKLAARKRKRAKQIQQFIGSLATYGGLGAIIGLVLFFVAEPKIGLAGGFGLAVLALSFKYPMLGLWGFLMYLPFAGTVTYWVGDGGPIFQLAKDGFYIPAIIAISLWCKKTGNPFIIPKSIKNPLYALLGLCLITLFLVNGVQHFNPPQPGDKAIPMGILGLKVMIGYLPLITGAYYQLKSKKELLFVARLTLILAIICCLLTIVQYQYLSSGKCNGTRGQTGDALFKASLEAKCLVGGALVFSPSQGMIRLPGTFVAPWQWGWFLISNAAFTFAVAFSDPSSLWRMGGLFGMAVVFINAAISGQRIALALVPTTTIILLILTGQLANFKRLIPIGAGLAVILGGLIVSNPVIVQERINSFVGRWNASPPTAFISEQFEQSNHAQKGFFGIGLGRATNSARVFGKTKLIETYYPKLIYEIGPIGTIAMLVLLTNITVSTFKAYRSVKDKNMRSLGASYWVFVLIISYNTYYYPLDVDPVAVYYWYFAGVIMKLPEIDKIEQIKLKEAEEN
>NC_008312|1661571:1764252|1740338_1741796_-|WP_011610857.1|DBSCAN-SWA
MPISLTEAKNLLSDLLSDYSSQVDYLAIRLEKSEETDILLRGHKIETLSEGISIGGQVRACYKGAWGFASFNQIYTLKDRIEEAIAAAKLIGKEETILAPIPIIQETHVVSLTGKNPRYISLASKKELCEHYGQVLRSVDPRITNVSVRYGDSTQKTILATSEGTILEQSWTDMEMRFAATARNGDTVQTGRETTGSRKAYEDLTNLDAQVRSAAQRAVNSLALPIVQGNAYTVVIDPILTGLFVHEAFGHLSEADMAYENPDLLEVMTIGRVFGPENLQIFDGAKVEPLLGGAGEEVHRGSYVYDDEGTLATTTQLIQDGVLVGRLHSRETAGKLGEAPTGNARCLDYRYPPIVRMTNTWIAQGNTPVSDLFADIKEGVYACNWFGGMTNGEIFTFSAGEAWMIRNGELAEPVRDVTLSGNVFNTLADIEAIGDDFHWDESGGCGKGEQNGLPVGCGGPSLRIGNVVVGGDTSEVRKREIRSQK
>NC_008312|1661571:1764252|1692629_1693406_-|WP_011610831.1|DBSCAN-SWA
MKTVVITGISGTLGSAMGKAYKSRGWQVVGVTRQPNLEGNFFDELCISPQETIEDAKKLFEYDPDVVILNAGQIETEVGEGGIPVVELVESMNRVNYSWPAVVGTEAAKLARSRCLDVIAIGSIADGSPSCFGPVYHSGKIALHYFWSGVGPIVYHSSKNMIRLRLYRPGVIAGKFAWAPVNRLNDKAYKIRENRVNSAPPADQVAEKIVNWIENSKEWVGTYDEPFGFKIFKYLFALFPNFFYRLQLYGWPKGSKFM
>NC_008312|1661571:1764252|1674905_1676414_+|WP_011610824.1|DBSCAN-SWA
MLTKLWSFRGRYRILHLTWFAFFLSFVVWFNLAPLATALKEDLGLETSQIRTIAICNVALTVPARIIIGMLLDKYGPRITYSLLLMYAAIPCIGFALAQNFSHLVISRLALSIVGGGFVIGIRMVAEWFPPKEIGLAEGIYGGWGNFGSAGAAFTLPTIAAWLTFGSGDVLNWRVSIALTGIIAALYGVFYFFNVLDTPPGKTYQKPKCARGLEVTTPKDFLFLVLMNIPLTGVLCLLGWRLSKVGFLSTSQLYIVWLVLLGLYAFQTYNCWITNKELIAQEKHYPPSDRYKFSQVAILELTYFVNFGSELAVVSMLPAFFENTFGLSKTMAGMIAASYAFMNLVSRPGGGLISDKLGSRKLTMTVLTVGMAIGYLTMGNVKGSWWLPAAVLLTMLCSFFVQAAEGSTFAIVPLIKRRVTGQIAGNVGAYGNVGAVLYLTLYSFLPEGAIGDKIFFEVIGVTSMIVAFICAFFLKEPEGSFAEHHEGEEEVQIESHTLFAEE
>NC_008312|1661571:1764252|1682016_1682154_+|WP_155994314.1|DBSCAN-SWA
MVKSYKQTNLWRQTSPPLNRILDKLPFVLYQVIETFVNFDPPRGG
>NC_008312|1661571:1764252|1749581_1749935_+|WP_011610861.1|DBSCAN-SWA
MDYETARQFLIDQGTALETKINPDAFLMRLEQGKPPIPGQVTNILLALKISFETLQGDPLLDRELVAGLYLLAIESLKLFEAGRRKRVMWPPLLKEDIERITIAVKNIFSGVVSKVK
>NC_008312|1661571:1764252|1720307_1720550_+|WP_052845808.1|DBSCAN-SWA
MRQINSVQGFIERFPRVERVIMDGTERPVQRPTHSEKPKLNYSGKKKRHTRKHLVAVNQNKKVLVLSQAREGKLHEVEVP
>NC_008312|1661571:1764252|1739338_1740091_-|WP_011610856.1|DBSCAN-SWA
MTQMYHSRQRQLKSLVEKLSISQQALIKWNLLDLALTHSTVSSTHNNEKLEFFGDAVVRLVAAQLLLENYPNCSVGEFTAIRSILVSDRSLAQIADKYGWSRYLLVSKSAAGDKVGRERRLADSFEAVLGALYLSTNNLELIRPWLDSHFERLIAEIRKDPACHSYKAALQELTQGYYKTLPNYQAHEVNKIYGDRERFFAEVWFKGQKLGVGKGPSIKAAEEAAAKSALDFLQQSGIQNIIKEEKDKKE
>NC_008312|1661571:1764252|1751416_1752841_+|WP_011610862.1|DBSCAN-SWA
MSNLILFWHRRDLRISDNVGLTQASQEGQTVVGIFCLDENILKRDDIASARVTYMIGCLQHLQKRYKQIGSQLLIMSGKPIEAIPKLATFLEAKAVYWNLDVEPYSRKRDRQVKENLEAANIQVKTFWEQLLHSPEEIFTSTKKPYSVYTPFWKNWQGKKKSNPLNTPVLKGLTEDQLQYTKKIGVIDLPTAKQLGFNWDNKLILEPGETAALEKLEKFSNGAISSYQEQRNFPSLDGTSQLSVALKFGTIGIRTVWAKTQELIENCYSSEVFENIETWQKEIAWREFYQYVMYHYPELETGPYREHWKNFPWKNNKAHFQAWCEGNTGYPIVDAAMRQLNETGWMHNRCRMIVASFLTKDLIINWQWGEKYFMQNLIDGDLCANNGGWQWSASSGMDPKPLRIFNPVSQTQKYDPEGEYIRQWVCELRSVDTQYLVTGKIPAEEREAIGYPLPIVDHKKQQQLFKDLYREQKN
>NC_008312|1661571:1764252|1736341_1736518_+|WP_155994317.1|DBSCAN-SWA
MSKPIKILLISIFAGSIFSILSLSNNQNSKEISQALESGVTMTSTIASLLISLKDSNE
>NC_008312|1661571:1764252|1665755_1666877_-|WP_011610820.1|DBSCAN-SWA
MEAISVIINNITTIKIMNIPVITILFICLVLITTLVFKRLLSIIVIKRIEALTSKTKTTLDDQLIAVLKKPIGWFIYLLGLWIIQLILTDYISPQLNQTITGIINLAIVGNFALIIYRISPILGEFFIILSAQTDTELDDIISPYIPKLLRLTAIVIFGLKVAELLLGASATALLGLIGGAGLTLGLLFKDFVGDWLATIIIYSDSLYRIDDWLLLPSGRWAEVKHIGIRSTTIYIGFEGATLKVPNSKMIDGNIKNLSQQPNEKKKAAIDLYIKIDGISARKIAYLNDKIRGIPKSIDLLYDSCVVRFNGLEKNARVIRVIGFTNDLDNYSRAYDQLNLAILALLEQEEIDLFDVNILSDTETYQNWQSSQN
>NC_008312|1661571:1764252|1758176_1758362_-|WP_011610864.1|DBSCAN-SWA
MVANSVYENNDLRFETTATVELIIRLPTGGNTGERNSDLNFQLRAWKRQNNQDLRKDSIYI
>NC_008312|1661571:1764252|1758519_1759998_+|WP_011610865.1|DBSCAN-SWA
MVSQFKKNLSRLKSQLKLISLVGTVIINFSFPVPAFGAFLTNWFFDPDNNQLQFTLPAGTTPTYSVESKPTRLVVYIEDTKVSVNVTELYPAGLVRRVSLSQERMQQAKVIIDFAPEVAISAKKVKLEQVEAPENSWKLRLLVGKEKTSTPRETKVLNGDAVTLTTKSTETTELEVDSFTPTTTSIETTKIENYESTKAEEDQAFTPPKQNRVSFQQRAPKVEFPLPNPALLAEPSIPFLVIPTEKRDGVIFPLIDTSRAQQSPTASSEISELPPLQGIEIENAFVPPPLDPETVEELNDRTTKSVDVISFGEPLPGTSGKNQLEDDASILIEAGKIISLIYPTSELELPQGVEIQEVLLLQEAITDESGRIIVPARTPVVGSFKTFSHGSQFIARAIYFNNRLIPFDARSQLLEGDLDFNEKVLAGSSTGSGLALLLLTGSGFGFLAGAALGAGSVLFTAPHSVTIEPGLIVEVRVVKDLPRSRFYDTSSF
>NC_008312|1661571:1764252|1705963_1706263_+|WP_011610841.1|transposase|DBSCAN-SWA
MTEIELIVDSTEQDIFRPKNDGKQKKYYSGKQKSHRLKNQIIITDNGKKIVDVIVGERGPESDIILFKKQQKKFDKEQRFQGDKGYQGGSRIDRPKKKK
>NC_008312|1661571:1764252|1662562_1662811_-|WP_011610818.1|DBSCAN-SWA
MCICVNCHYVDQCVTYHAVETQHEQLHLTENPDFDPVEPTINVNIRPKQNEIEMEWDVVGCESFLEEMGKWAKLRPGELIPT
>NC_008312|1661571:1764252|1663279_1664551_+|WP_011610819.1|tRNA|DBSCAN-SWA
MLINSLSALSPENWPFEAKMLPQNVYLVGGSVRDALLKRKTTYLDLDFIILDQAVSIARNIAKEYQAGFVVLDAERKIARVVFKGTTVDFAEIEGNSLKEDLWRRDFTINAIAYNPFTNELIDLFNALKDLQDGIIRMVKSENLKEDPLRLLRAYRQAAQLGFIISPETQTTIREFAPLITQVATERVQTELGYLLSHPQGMIWIEKAWKNGLLSDYFPAATENLGIGKKVEIVVEKLQKNWSTLKVELGSGVRNTVKTSLLAIAKLAILVNSNPQKAEVELMRLKYSNAEIRSTIAVLKSLEKLSEIEVLHMSVREQYFFFQQIGKNFPALAVVAVAKGISMEEINCLIERYINPDDLVAHPTTLLSGNDLITALKLPKGPIVGQLLTEIQIARAEENILTQDEAIKLAQKLIAFRNDPSSF
>NC_008312|1661571:1764252|1709718_1711734_-|WP_011610843.1|tail|DBSCAN-SWA
MSPIMPFEFFWCYEPEDEDEEEYCQCLLLGTPETVTPLHIGLRNTLSDKVITIASIPEVTIASAEHYHFKLTFQPGILADPDQIKIEETESWSLYIKTDPNYVCLYLLWTEAPIILNPGQETEVILTGVAGLANNSATEAILTEVIDLANNSASARAVADVNINWIIGEKNISIAEVKFPGQDDSYDTTTTLTLEMKKTSGKSNIPLYVGFVGSNKVFNTHDNNSRLQLRITNTNLSNADNSAITFNYNANSDQCSQLVIVLEVGDKDSVPWALGTQDDVNGVNITINNWQQLSDGPEEIQVNGQTKALEWTFIPQESDVVLNSQETLLINLDGITTAHPTGETNLYLRYQYIDGYRDGQFVCQIEKAPLVFDEKVRIGTNKSLDGLLTVKDGISLDAPGEINHTGTLIFRSDTDTSNDDISVKFYKQKNDLPLMELTSRGDLQFPAKSGQTGQRINLWGPEYGVGTQGNTTYFRTNGYFAWYLGGSHEETSTTPGDGGRTQMLLDQEGNLEVGCGRIKDSTGWVVPVGTIVPYAGLTAPEGWLLCNGQSYDWEQYSELYKVLDEIKVLPDLKGRFIIGVGDKDGYSYSLNAKGGEEKHTLTKDEMPSHDHSKGEYKFILKKDGKVTTSNNVNNSLREPNLGSCEALQVIGNNKPFENRPPYYALNYIIKT
>NC_008312|1661571:1764252|1737999_1738809_-|WP_155994647.1|DBSCAN-SWA
MMLEESYKNNEAIFLNKIADKLMVKDKTRLVFTERFKIDNDDLNNQKLADVLSSNLLQNASKKATSDIILRDSLKTIFKKLETEGCDFEGAKRDKVKIAKRWLREIIYPWHALKDMATFTDKMGLVIQGITQLDTSKTVSRYPSVIPLNSEVKFEVQLERSGYLTLLKKGASGVFYCLSPSCLASSPIFDGGVASLPMEGAPVNHFKLNGKIGVEEIIAGISHERPNLDWLPAADQLPLLLKGEHLQEFLMYFKAELGSTLWYMHYQVV
>NC_008312|1661571:1764252|1760504_1761014_-|WP_011610866.1|DBSCAN-SWA
MKRTNQTTSQVSRFNYATLAILGGVFVLGIGIGIAFSSTANFTPQNMASSEFIDRSVPNPEICVQFGASAMVMNMRVFLTLNPFNVYVSQPGLKPGCVIRRSNWEILQQRKLVNNEQVRDCKNRMNTFGYTGNINDEPEIDCIYQNDSAQNLFFKNMGPGFAPPENNNF
>NC_008312|1661571:1764252|1700475_1700718_+|WP_052845808.1|DBSCAN-SWA
MRQINSVQGFIERFPRVERVIMDGTERPVQRPTHSEKPKLNYSGKKKRHTRKHLVAVNQNKKVLVLSQAREGKLHEVEVP
>NC_008312|1661571:1764252|1700207_1700489_+|WP_081432400.1|transposase|DBSCAN-SWA
MNLCWSPLGKCMSKHCTRSPRQRSVGGGLLARLRTLQDKLFDILFYFKCYPTFDLAGILFDIDRSQAHYWVHRLQTMLEAALGEKKARCIASN
>NC_008312|1661571:1764252|1688759_1690061_+|WP_011610829.1|DBSCAN-SWA
MTKKLNSEHILVVDDVQANLKVIVKTLTNEGYKVSTAISSDQALKQISYDLPDLILLDIQTSGIDGFEICQRLKENPEMKDIPVILMAVPSNIKNIVKGLTLGAVDYITIPFQTIEVLSKVKNHIHLQQLKKNLEKEVAKKTYELTQALEQLKASQVKPIKSEEMLVTGELMAGVANEFNHPIGSIYSNSFYLETYIKNILEHLFLYQKNYPNPVAEIIQSAEDIDLDFIIEDFPNIITSIKTSSERIKYLSSYLQKFRKQSVITAHKSIDSALLILKHRLKANQYRSGIKVVKKYGDLPKMKCLPGQLIQVFMNIIYNAIDEIDEFGKKVGFSNCKFEPKIVINTLMSHDKKEVIVTIKNNGIGMSEEVKRTVFDKLSNTRALAKGTSLSLSIAHQIVVNNYHGKLCCESIINKGSKFILQLPITEMSKNMR
>NC_008312|1661571:1764252|1720039_1720321_+|WP_081432400.1|transposase|DBSCAN-SWA
MNLCWSPLGKCMSKHCTRSPRQRSVGGGLLARLRTLQDKLFDILFYFKCYPTFDLAGILFDIDRSQAHYWVHRLQTMLEAALGEKKARCIASN
>NC_008312|1661571:1764252|1681220_1681523_-|WP_071820740.1|DBSCAN-SWA
MTTITNNNIEQVILDNLKLLPPEKQQEVLDFIQFIQHKLNHSQVNYNNQLSLKEIARLPIVERHKLLTPSIDKTAEDFLNDPELTEFFILDGEDWETGDE
>NC_008312|1661571:1764252|1705097_1705265_+|WP_155994316.1|DBSCAN-SWA
MLTLKVNYHQKLLQQFWDDFWSDTEIYWPGTDTPILSTALRLPSEFLELFTTVSR
>NC_008312|1661571:1764252|1695935_1696739_-|WP_011610833.1|DBSCAN-SWA
MLQLSLENIKAKFRKILIYKIGAKLLGYYEKLIPSYSLIGNTAFLEPHHFEWVNEIDANWILIRKELDELLKYRDDLPNFQDISPDQADYTSPDDLWKTYFMYGYGIKAEKNCQRCPETTRLIEKIPGMKTAFFSILMPGKHIPEHRGPYKGVIRYLLALKVPEPKEKCRIRVGNETRHWEEGKSMIFDDSFPHEAWNETDGVRAVLFLDVMRPMRFPLSFLNELMMKIIAISPYIQDANINQKHWEDRLEKLFGKENQKEKVSSST
>NC_008312|1661571:1764252|1667738_1670750_+|WP_081432526.1|DBSCAN-SWA
MSYFREWTNSCVDDQLIHLNVVPLEGQRAYEFLFYSDAIPRRNDGRVTSEILNRYQHIEEGGWWCSGIDLLSGEEDFWGCFKPSQPRHSYDEKKIIKYEHPPKTPTSLFALKIPLHLWHKIASHYQLTILPEDIDNNQPDFGFWQWFIAHPQIPLCITEGAKKAGALLTASYVAIALPGVFGGYRVLRDEYGNRIGKQHLIPQLEKLINNTREIYIAFDQDTKAKTIKNVNAAIRKTGYLLIKKGCKVKVISWNPELGKGVDNLIANHGKNVFDEAYKKALPLELWKAKSFIRLTYPVNLRVNSRYLSEQNIFNSIDNNNNNLHKLDDIDLDYSINFPAKLIGIKSAKGTGKTKFLEKIVSEAVARNQKVLVIGHRVQLVQELCQRFGLKYITEVNSKSPDKLLGLGLCIDSLHPNSQANFNPETWSDGIVIIDEIEQVIWHALNSNTCRKSRVKILRCFKALMQNILGGAGKVFIADADLSDISIDYLQALAGVKLEPFIVQNDWLPGEKEAWKIFNYPETTPKRLIADLQKHIREGGKPIVCLSAQKLTSKWGTRALEAYLKKQFPKLKILRIDSESLAEVNHPAYGCIKSLNQVLLKYDIVLASPSIETGVSIDVQGHFTSVWAIAQGVQGATSVCQSLGRVRENIPRYLWVANCGFNQVGNGSTSITSLLNSEQRLTQLNIRLLQQSDFDSLDDLEVGFQAESFLCWAKMAVRFNAGMNQYRESVLEFLRIEGQQIIEVSAEALPENLEEKKSSETPEEINTLQEAIAIVIKQNYQTECEAIATAKSISLFEYQKLTKRLSKPIQQQREQRKFELMLRYSIPITAELVQKDDRGWYQQLQLHYFMTVGRPYLPARDGEVVKKLLELGKGNIFIPDFNDSLLGAIIGVIELLKIPSLLKDKKRELKNIDPDLQLLGKTALSNRTEIKTILGIGLAANSSPIIIVRRFLEKIGYSLECLRTETHHKKRLRIYRIFHPDDGRFEVFQQWLSSSHNSKVRTCV
>NC_008312|1661571:1764252|1745213_1745681_-|WP_011610859.1|DBSCAN-SWA
MPLILSSSYFQKILTHAEISYPNECCGLLLGQKNQETKTVIEVWPAENAWQTEADEYWPEQTEFTEEKRYAISPELMLKTMKSARERHLSIIGIYHSHPNHVAIPSEFDRTYAWPEYSYVIISVEKGQAIDFLCWSLDDNHQFQPEKIIKIKDKQ
>NC_008312|1661571:1764252|1743769_1744945_-|WP_011610858.1|DBSCAN-SWA
MLNPNLEQIQLNTEEYQRYSRHLILPEVGLDGQKRLKAASVLCIGTGGLGSPLLLYLAAAGIGNIGIVDFDIVDSSNLQRQVIHGTSWVGKPKIESAKNRIHEINPYCQVDLYETRLSAENALDILKSYDVIVDGTDNFPTRYLVNDACVLLNKPNVYGSIFRFEGQATVFNYEGGPNYRDLYPEPPPPGMVPSCAEGGVLGILPGIIGVIQATETIKVVLGKGKTLSGRLLLYNSLDMTFRELKLRPNPIRPIIEELIDYEQFCGIPQAKAQEAETKMAIPEMTVQDLKQLFDSGKKDDFVLVDVRNPNEYDIAKIPGSVLVPLPDIEQGPGVTKVKELMNNRSLIAHCKMGGRSAKALGILKEHGIEGTNLKGGITAWSKEIDSSVPQY
>NC_008312|1661571:1764252|1699720_1699915_-|WP_155994646.1|DBSCAN-SWA
MTGNVSRGGNWNLEVIFAQLKSALAFTPEVKASYAGVLANIMVNTTNDIVDDSDRVTFSKESYY
>NC_008312|1661571:1764252|1706271_1706448_+|WP_081432402.1|DBSCAN-SWA
MSYKVKKENQKKAQKIIFVEHVIRLIKIFKVARERFRLKESNYEKVILTICGLVRLRD
>NC_008312|1661571:1764252|1753870_1756033_-|WP_011610863.1|DBSCAN-SWA
MSKNKKNTVETPIEKKLSNPQYYFNRELSWLEFNRRVLSEGLDPRTPLLERLKFLGIFSSNLDEYFMVRVAVLKKQIEAEVHKLTPDGRTPQEQLDEINQILLPMVSLQHQFFEQNLRPELRKNGIDILNYIDLDREEKTYLRNYFEEHIFPVLTPLAIDASHPFPYLSNLSFNLAVMLKNPDTQEDLLARIKVPKILPRFLCLPEKLQIEQKAKTLNWTGVPLEQVIAHNLGALFPGMDIQEYHVFRITRDADLAVQEDEGDDLLLVIEKELRKQRIGGTVVRMEINPTMPSKLKKTLMDNLELSEKDVYTVDGLLDLKDLMSFLGLPLPHLKDPTWTSTMPPRLRHYGDELRIPDLNENNKIDFFEVIRQKDLLLHHPYHSFASTVQGFISQAAHDPNVLAIKMTLYRTSGNSPIVNALIAAAENDKQVAVLVELKARFDEENNIQWARKLEQYGVHVVYGLAGLKTHTKIVMVVRQEEGHIRRYVHIGTGNYNPKTAKIYTDLGLLSCRPELGADLADLFNFLTGYSRQQSYRKLLVAPVNMRDRFMKLIRREIENCQNGDTGRIVAQMNSLVDPKIITSLYKASQVGVKIDLIVRGICCLRPGLKGISDNIKVVSIIGRYLEHSRVFYFYNKGKEEVYIGSADWMPRNLDRRIEAIIPVEDSEITKELQEIMGILLSDNRQAWDLQPDGKYIQRRSTENFPELACHKILMETVANT
>NC_008312|1661571:1764252|1725762_1726743_+|WP_011610848.1|DBSCAN-SWA
MNLPSISVVIPTYGREEPLIDTIADVIKQDYPNFEVLVVDQTGTHKPETQVYLEKQANAGRIKLFRLTWASLPGARNYAVRRCSGEIILFIDDDVRLQKGFLAAHAGNYIDRPEIGAVAGRVFDRMKLGDSGGELEIEDLPPEASDPGIAWYHIDLVHTVKAQRVISARGCNMSYRREVFTKYGLSFDERFRGSAVREESDFCLRLRRTGYHIWFDPEASLVHLGEESGGCHDISTRSLKYQITFYHNHFFMGLKNLTPHQCLRFFGKLFDCHVLGNPPCYKSGSPIKIITRGGFYILGFFSAVQTRIKSIWDDGQIYTKKVNTQE
>NC_008312|1661571:1764252|1676565_1678770_+|WP_011610825.1|DBSCAN-SWA
MKTTKTACPYCGVGCGLEVSPPATPGKVTNRDSKGNPTWQVRGDRSHPSSQGKVCLKGATVGEALDKSRLKYPMMRNTLDEAFRRVTWEEAFRRIVNQIQKVRFSQGPDAICMYGSGQFQTEDYYVAQKLLKGCLGTNNFDANSRLCMSSAVSGYIQSFGSDGPPCCYDDLEKTDCAFLIGTNTAECHPIIFNRLRASKKRNKKVKMIVVDPRRTKTAEVADLHLAIRPGTDIDLLNGIANLLIQWGLLDAMFIDECTKGFPEYVNIIRQYPPGLVARHCGIRLDELETAARYWGKSERVLSLWSMGMNQSSEGTAKVRTLINLHLMTGDIGKPGTGPFSLTGQPNAMGGREAGGLAHLLPGYRMVKNSQHRAEVEKLWELTPGKISDVPGRSAWEMIMALERKEIGCLWIAATNPAVSMPDLKRTKAALLRSPFTIYQDAYYPTETAEYAHLLLPAAQWGEKTGTMTNSERVVTLCPAFREPLREAKADWEIFAEVGRRLGFTNHFNFADSEAVRAEFLELTRDRPCDMTGITYQRLQEKGPTQWPCPDSSGVSQERLYTDFRFNTPDGRARFAAYYSQGLAEPPNPDYPFILTTGRLYGHWHTQTRTGRIEKIRKMYPLPFMEIHPQDAQRLEISDNDWVEVRSRRGYSRFPAKITKAITPGTVFVPMHWGALWAHQAEANTLTHPQACPESGQPELKACAVQLQPVKFQAAPIALWASKKSTPLGEVKSSK
>NC_008312|1661571:1764252|1701089_1701224_-|WP_081432401.1|DBSCAN-SWA
MNQISKSLGKGHNVDTVHIISHGAKGAMYLGNSILNLDNRVVGK
>NC_008312|1661571:1764252|1690504_1691377_+|WP_011610830.1|DBSCAN-SWA
MDFYIVDVFAETKYSGNQLAVFTGAEVANLSDEKMLQIAREMNYSETTFLLSSEQQNGGYDVRIFTPTKELPFAGHPTLGTAYIIQRKIIKSLVEQVVLNLGVGQIPVSWKGEVLWMSQNVPTFAQKHQVETVAEVLNLEVVDIDTRFPIQEVSTGIPFIIVPLKSLVALKKAKVNLDKYYQFIQTTKVTEILIFCPETYKDIDDLSVRMFAPYLGITEDPATGSANGCLAGYLAEYNYFNQRKIDIRVEQGYEINRPSLLLLQAEKKAGKIEVFVGGNVVMIAQGKFVA

Homologous phage analysis in the prophage region

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_011610817.1|1661571_1662207_-|tRNA	tRNA (adenosine(37)-N6)-threonylcarbamoyltransferase complex dimerization subunit type 1 TsaB	NA	NA	NA	NA
WP_011610818.1|1662562_1662811_-	Ycf34 family protein	NA	NA	NA	NA
WP_011610819.1|1663279_1664551_+|tRNA	CCA tRNA nucleotidyltransferase	A0A0U4J6Z1	Vibrio_phage	2.0e-19	35.8
WP_011610820.1|1665755_1666877_-	mechanosensitive ion channel family protein	NA	NA	NA	NA
WP_081432526.1|1667738_1670750_+	DUF3854 domain-containing protein	A0A2H4JHB4	uncultured_Caudovirales_phage	2.5e-12	21.3
WP_011610822.1|1671147_1671966_-	methyltransferase domain-containing protein	NA	NA	NA	NA
WP_011610823.1|1672963_1674496_+	ferredoxin--nitrite reductase	NA	NA	NA	NA
WP_011610824.1|1674905_1676414_+	MFS transporter	NA	NA	NA	NA
WP_011610825.1|1676565_1678770_+	nitrate reductase	NA	NA	NA	NA
WP_011610826.1|1680862_1681228_-	type II toxin-antitoxin system PemK/MazF family toxin	NA	NA	NA	NA
WP_071820740.1|1681220_1681523_-	DUF2281 domain-containing protein	NA	NA	NA	NA
WP_155994314.1|1682016_1682154_+	hypothetical protein	NA	NA	NA	NA
WP_044137191.1|1683869_1687460_-	methionine synthase	NA	NA	NA	NA
WP_011610829.1|1688759_1690061_+	hybrid sensor histidine kinase/response regulator	NA	NA	NA	NA
WP_011610830.1|1690504_1691377_+	PhzF family phenazine biosynthesis protein	NA	NA	NA	NA
WP_011610831.1|1692629_1693406_-	NAD-dependent epimerase/dehydratase family protein	NA	NA	NA	NA
WP_011610832.1|1694035_1695550_-	GMC family oxidoreductase	NA	NA	NA	NA
WP_011610833.1|1695935_1696739_-	aspartyl/asparaginyl beta-hydroxylase domain-containing protein	S4VR59	Pandoravirus	1.8e-21	32.0
WP_011610834.1|1696855_1697746_+	transporter	NA	NA	NA	NA
WP_155994315.1|1699321_1699525_-	hypothetical protein	NA	NA	NA	NA
WP_155994646.1|1699720_1699915_-	DUF4347 domain-containing protein	NA	NA	NA	NA
WP_081432527.1|1699958_1700078_-	DUF4347 domain-containing protein	NA	NA	NA	NA
WP_081432400.1|1700207_1700489_+|transposase	DDE transposase family protein	NA	NA	NA	NA
WP_052845808.1|1700475_1700718_+	hypothetical protein	NA	NA	NA	NA
WP_081432401.1|1701089_1701224_-	DUF4347 domain-containing protein	NA	NA	NA	NA
WP_011610838.1|1701533_1703168_+	alpha-D-glucose phosphate-specific phosphoglucomutase	NA	NA	NA	NA
WP_155994316.1|1705097_1705265_+	hypothetical protein	NA	NA	NA	NA
WP_011610841.1|1705963_1706263_+|transposase	transposase	NA	NA	NA	NA
WP_081432402.1|1706271_1706448_+	hypothetical protein	NA	NA	NA	NA
WP_011610842.1|1707586_1709560_-	hypothetical protein	NA	NA	NA	NA
WP_011610843.1|1709718_1711734_-|tail	phage tail Collar	A0A218M5J0	Arthrobacter_phage	1.6e-10	26.5
WP_011610844.1|1712153_1715477_-	hypothetical protein	NA	NA	NA	NA
WP_011610845.1|1715630_1719581_-	hypothetical protein	NA	NA	NA	NA
WP_081432400.1|1720039_1720321_+|transposase	DDE transposase family protein	NA	NA	NA	NA
WP_052845808.1|1720307_1720550_+	hypothetical protein	NA	NA	NA	NA
WP_011610846.1|1721595_1723065_+	phosphoglucosamine mutase	NA	NA	NA	NA
WP_011610847.1|1723361_1724966_+	hypothetical protein	NA	NA	NA	NA
WP_011610848.1|1725762_1726743_+	glycosyltransferase family 2 protein	NA	NA	NA	NA
WP_044137193.1|1726891_1727725_-	glycosyltransferase family 8 protein	A0A2P0VP84	Tetraselmis_virus	3.3e-07	22.3
WP_011610850.1|1728099_1729266_+	glycosyltransferase	NA	NA	NA	NA
WP_011610852.1|1730624_1730951_+|transposase	IS1 family transposase	NA	NA	NA	NA
WP_011610853.1|1731394_1735918_-	tetratricopeptide repeat protein	NA	NA	NA	NA
WP_155994317.1|1736341_1736518_+	hypothetical protein	NA	NA	NA	NA
WP_052845750.1|1736813_1737596_-	DUF4384 domain-containing protein	NA	NA	NA	NA
WP_155994647.1|1737999_1738809_-	DUF4384 domain-containing protein	NA	NA	NA	NA
WP_011610856.1|1739338_1740091_-	ribonuclease III	NA	NA	NA	NA
WP_011610857.1|1740338_1741796_-	TldD/PmbA family protein	NA	NA	NA	NA
WP_011610858.1|1743769_1744945_-	molybdopterin-synthase adenylyltransferase MoeB	NA	NA	NA	NA
WP_011610859.1|1745213_1745681_-	M67 family metallopeptidase	NA	NA	NA	NA
WP_011610860.1|1747475_1748141_+	FHA domain-containing protein	NA	NA	NA	NA
WP_011610861.1|1749581_1749935_+	hypothetical protein	NA	NA	NA	NA
WP_011610862.1|1751416_1752841_+	deoxyribodipyrimidine photo-lyase, 8-HDF type	A0A2H4UV63	Bodo_saltans_virus	3.4e-68	33.8
WP_155994318.1|1753133_1753292_+	hypothetical protein	NA	NA	NA	NA
WP_011610863.1|1753870_1756033_-	polyphosphate kinase 1	NA	NA	NA	NA
WP_044136443.1|1757930_1758164_-	hypothetical protein	NA	NA	NA	NA
WP_011610864.1|1758176_1758362_-	hypothetical protein	NA	NA	NA	NA
WP_011610865.1|1758519_1759998_+	AMIN domain-containing protein	NA	NA	NA	NA
WP_011610866.1|1760504_1761014_-	DUF3172 domain-containing protein	NA	NA	NA	NA
WP_011610869.1|1763964_1764252_+|protease	ATP-dependent Clp protease adapter ClpS	NA	NA	NA	NA

Sequences of DBSCAN-SWA_4

Nucleotide sequences of DBSCAN-SWA_4

>NC_008312|1843886:1944867|DBSCAN-SWA
GATGATTCAAAGTTGGACTTATTTTCTTTCTATTAATGATGACTACAAGGTTTATACTTACTTAATTGAGGATTGCGATCACAAGGTCAATAAAACAGCCATGACCAGAGTAGAAGGAGAAAAATGCCGTCGTTGCTACTACTTAACTAGGTTACATCGTAAAACTTTATGCTATTCCAAATCAATTGATATGTTATGCAAGTCAATTGTTTGCTGATCTATTATTTGAAACATCGGCACGTTCCTCAATTCTCTTTATCATTCGTAATTGTGCAAAGCTAAATAAAATGTAGAAAAGTTTTTGAGAAATGGTATTAGTTTTTGATGTTTTAATTTCAGGCCCAAAACAAAAATATAACTAATGCCAACCACTATCAGATTAAAGACTTCAGGCATTTATCTTCATATCAACTTTTCTTTTTGCAAGATGTAAGTTTCCCTGTTTACCTCCCACATTTTCTTTAATCCCTAAAATATATAAATTATTAATTATTCGGTAATCTAGGTTCCTTCAAGTCACTGAGTTACAGTTGTTTTTTCTGTTTTCTATTCCCGGCAAATTGCGCCCTTACTACTCCTTACAGCAAAAAATAACTTAAACTAGGAAGAAGTAAATATTCATAGTAATTCATTTTCTATGCCTTTATTAACAGAAAGAACAATTGAAGTTGGACAAAAACTACAAGGCTTTGAAGTCAAAGCTATTACTGACCTGAAGCAACAGCGAATGGTGGCATATCAGCTAGAACATATCAAAACAGGTGCAAAACTGTTACACCTATATTCAGAAGATGCTGAAAATCTCTTTTCAATTAGTTTTCCCACTCCCCCTCCAAATAGCACAGGAGTATCCCATATCCTAGAACATTCTGTATTAGCAGGTTCAAAAAAATATCCTGTACGCGAACCATTTTTTGAAATGCTAAAAATGAGTCCAGCAACCTTCATTAATGCCATGACTGGCCCTGACTGCACTTACTATCCAGTTTCCAGTAAAGTTAAACAAGACTTATTCAACTTGGCAGAAGTATACTTTGACGCTGTATTTCACCCACTGCTAACCGAAAATACGTTTAAACGAGAAGGACACCACTTAGCTCCTACCGACAAGGAAAACCCAACAGGGGAATTAAAATTTACTGGGGTAGTTTACAATGAAATGAATGGAGCTTTTTCTGACCCTGAACAAAGGTTAGATAGTATTGCTAACCAAAGTCTATTTCCTGATAACATTTATGGTCTTGAATCTGGAGGGAACCCCCAAAATATTCCTGAACTCACTTACAAAGACTTCCGTGACTTCCATTCCAGCTATTATCATCCCAGTAATGCTTACTTTGTTTTTTACGGCAATATTTCTACTCCTGAATATCTTGAATTTTTAGCCAAAAAGCTAGAAGCTTTTGAAAGACAGAAACCTAATATCAATATTAATCCTCAATCTCGCTGGAGTGAACCTCGTTTTAAAGAAGATTCCTACCCTATTAGTGCAGCGGATGAAACAACACAAAAAACTTACATAATGATCAAATGGTTGGTGGGAGATAGCACTGACTCTGAGGAATGGGTAGCTTTAGATATTCTCAGTCGCATCTTGTTGGGAAATGAAGCGGCACCATTGAAAAAGGCGATTGTTGAATCCCAAATTGGTCAAGATCTACTCGGCTCTGGAGTAGATTCTGTGGGTAAGGAGGTTACTTTTCATCTGGGTATTCAAGGAAGCGAACCTAACCAGGGTGAAGCATTCAGTCAGTTAGTAATCAAGACTTTAAAAGAAATTGCTGAAGAGGACATTGAACCTAGTATTGTTGAGGCAGCGTTTCAACAGGCAATTTACCAACACCAGGAAATAGGTAGTATGTATCCTTTACGGATGTTGTTTCGGGTGATGCAAACCTGGATTTATAGTAATGATCCATTGAAGTTTTTACATATTAGCGATCGCCTCGCCGAATGCAAACAACGTTACCTGGAAAAACCTAGATATTTTAATAACCTAATTCGTGAAAAATTACTCAATAACCCCCACCGTTTGACACTGGTATTAAAACCAGATAAAGAATGGCAATCTAATTATGACAAAGCAGTAGTAGCACAGGTGGAACAAGTACGTTCTCAATTAACTTCAGAAGAATTAGAACGCATAGCTACTGAAGCAACAGAATTAGAAATAGAGTCAGGAACTCCTAATTCTCCTGAAGAAATAGCTAAACTGCCCCAACTACAAGTGAAGGACTTACCTGACAAACCAGAACATATTCCTACTGATGTCGAAGAACTTGATGGCCAAGTGACACTTTTAAGGAATCATGTGCTAGCAAATGGAGTAAATTATTTACAACTAGATTTCAGTTTGCGTGGGTTGCCTGAAGATTTGTGGTTGTATCTATCTATTTATATAGATGCACTGCGGAAGTTGGGTGCAGGAGAAATGAACTACGAACAGGTGGCTCGCGGCATTGCTTCTTATACCGGGGGAATTAGTTTTCAATCTCTGTTACGGACTTCTACTAAAGATGCCTATCATTCTGTGCGTGGACTTCGCGTCACCATTAAAACCCTAGATGAACAGATTGAACCAGCATTAGAGTTGTTACACAACATGATTTTTGCAGTTAATCCTCGGGATACAGCTCGACTACGGGAAGTGATGATTCAGTCTTATTCTCAATCTAATTCAGATTTGATTTATAACGGTATCTACACTGCTATATTGCGAGCTAGTGCTGGTATGACATCAGAAGCTAAGATTAGTGAGATTGTTAACGGTTTACCTCAACTGGAGTTGTTGAAAAAAGTATGCGATCGATTTGATGAACATGGGGCAAATTTGATGAGCAAGGTTGAAACTATCCGGGATTATGTAGCCAATCAACCTTTGACTGCTAGTTTTACTGGTTCAGATAATGCTTATAATGTGGTCAAGAAGACTCTCTCGGAGTGGGGTCATCAGCAAAAGCAACAAGAAGGAGATACTTTTGGTAGTCGCTTTGAACCAGTTTATAATATGCGGGAAGCTTTAGCAGGTCCAGTACAGGTGGCTTATTGCGTTCAGACTATGCCAGCTCCTCACTTTAGTGATGAAAGAGCGCCATTTTTAAGGTTAGGTACTCATTTATTAGGTTTGGGTTATCTATTTACAGAAGTTCGTCTTAAGGGTAATGCTTACGGTGCAGGATGTCGTTATAGTGGTTTAGGAAAAGTTATTTCTCTCTATTCTTATCGCGATCCTCATGTCAGTCGTACTCTTGATGTATTTGCTGGTTTGATAGATTATCTTAAGGATGTAGATTGGACTCAGATTGATGTTGACCGGGCAATTATTGCTACAATTCAAGATGATTCTCCAGTTTTGCGCCCAGAAGTAGCCACAAGCTTAGCTTTGGAACGTCATTTGATAGCGCAAACTGCTGAACTTAGGGAGGAACGTTATCAGCGAACGCTCAAAGCTACAGTTGCAGATGTGAAAGAAACTTTGTTAGATGTTTTTACTGCGGGGATGGAACGTAGTAATGTTTGCGTAATGTCTTCTCGCGAAAAATTGGAAGAAGCAAACCGTTCTCGGGAGGCGGATCCATTGACAATTTCTGATATTATGTAATATCAACAGGACTTACGCAATAATTTTGGATAGCTATCTCAAGCGTCTTAAACTACAACAATAATAGGTAAGTCCTGTAATAGTCTTTTGGTTTCTGGTTAATACATTTCTGCTATTGTTACCAAAAGCTATGTCATCGTTTACCTAAAAAGGTCAAATCTAATTTTAAGTTAACCAAACAACGTTTGAATCTCCCAGGGATGAATATAATCTTGAATTACACTTGCCCCTGGGAGATCGCTAACTACCATTAACAGTTGCTATTTGTGCCAAGTTGATATTTCTCTAAATACAGCTTAGATAAATAAAGGGATAAATTTAATTCTGGCTTCATAGCAATAAAAGTGGTAATTTATAAGTTGTTTGTAGTCAACTAATCTCCCAAATATTCAGGTTTCATAGAGATTATGGTTTAAGTACTATAAACTTTTTCCTATTCTATAAGTCAAGCTTTTTGTCCTGTACTTAGGAAAGTAAATCTTTTTAAGAAGTTCCACACGCTCTATCCCACAAACAATATGATTTTTTTGAACAGGAATTACTCGAAGACACTATATAAGTGTATATGCTTGCCAAGAGAGATAGAATTACCTGAGCTTTTGCGAACACTAATTTTTTTTAAGGGATATAGCTGCCATAGTTCCTCCCCTAGTGCTGAACAACAAAATCATCATAACTAATACAAAGATATGTTCTTTAAATTGATTTTAGCTCTATATAGATGTGGCAAATGGTAAAGATTTTTTGCTAAAATACCTGGATTATTGTATAATAATATTATTGTTAATTTGAGCCAACAATATAAATTTTAAATATATTAATTATAGTTAATAATTACTCAATTTTTATACAAATTATACGGTCAAAATTTTTAAAAAATTACCAAAAAATGTTAGCTGTGACATGATAAGTAATCATTTAAAAAAATAAAAAAATGATAATCATAAATAAAAAAAATGTTGGCAAAATATAACTTATACAGAAGCTTATTTGATATTTTATTATCTTTTTTAACAAAAAATATAGTAATAAAACTAACTTTTTTTCGTCAACAGTATAGTAGTAATGAGTATCAAGTAGTTTGTGGTGTATGAATAGCAAACTTTATATCTTTTAAGCTGAAATCGAAAATTTTGGCTCATAGGTTATCGAGTTTATGACCCAGATACTGAGAAAAAAAACCAATATATAAAAATATAAAATAAATAATTTTATACGTAATAAATAATAACAAATTACTATTTAAGATTGTATTAATAGATAATTTTTATAGGACAAAAAGAGCAATAAAATTGATAGATAATATGGAAAAATTTATTATTGCCTCTGCAAATAAATTGTTATCTTCGATAATACTGGTAGTATATAAAAATATAAAATTATAGGATAATTGATTTAGAATAACTTAGAAAAAATATTATGTAAAATAATTCAAATTAAAAGAATTATTTTGAGTTCAAAAAAAAGTCAAGCTATCATAGAAAAATATTTATCCTAAATTCAGCAGAATATATTGTCACTAATCATTTCAGTCAATCTTCAGTATATACTGTATAATCTGAGTCACAAACTAAATCTAATATCGAATAAATTATCCCCAGAATTAAGAAATTAAACGCAATTAAATTTTGTCAATTTCGTCGATTACAATATAAAAAAACCACATAGTTTTTGCTATTTTAGTCTGGAATTTATCAAAAAAATTAACAGTAAAAATAGGAAAAAATATTGATGAAGTTAAATACAAATTACTCTCAGATTATTTTCTTCAATAGTTAAAAAAATCTCACAATAAAAATCAGGGATATTTTTATTTTATAGGTGCTTTAACCCTTGTTTTAACAATGGCAAAAATCTTAAGGGGGTTGTTAAACTTTTAGGCGATCGCGAAGGTTCAGCTCCTTATATTGCTATCGGCAAGAATACGCCCTTATGTAGCTTCTTTGTGTAAATCCTGAAAGTATTAAATCCTTATTCTTTTATTAAGTTAATACTCTCTAATTTTTCTGAATACCATAACAAAGCCGAGCAAGTACTATTGGATTATTTTCCATCAAATCATTTGTTAGACTTTTTAAACCCTGTAAAAAGTGTTCCAAATTATGAGTTTTTGAACCGTCATTTTCGCAATCACGATCCTCACAGTTCCAATTCTGCCACCAATCTTGTTCTCCCAAACCATTAGCGACTACATCAACTTTGAATAAATAAATATTTGCTTGTGGTAATTCATTAGGTTTAATTGTATTTGTATAACTTAAATCACGATTTTTGCCTACTTCCCAATTACTAAATTGCATTGAATTGAAGAGTTTTTTTGCCATTATAGCCTCTGAAGAAATGAATTCTGTTGTTGACTCATCAAAATATTTACTTTCACTAATTTTAGCTTTTATAGAATTAGCTGATGGTGGCAATGTATACTCATTTAAAATCGGCAAATTAACCTTGTATTCAATTGGTATTTCTTTTGAGAAATTGGGGATTATTTCTAACAATTCAAATTCTTTACGCTTCGGGAATTCGATCGCTACTTTACCATTATTAAGAGAGAAGGGTCGCTTCAGACCTGATATTGGTTCGCCTGGGTTTTTCAATTCACTCATGACCGATAAATCATTTATAATATTATTAGGTGAAAAGATTGTAAATTCACTGTTTTTAATTAATTCTCCTCCATCCCGCTTGAGTTTTTCAAAGTAGTAGAGAATATGTTTGTAGGGACCTAAAAATATCACATAAAAAGGCCGAAACTTTTCTATTGGTTTCCCTTCAGTGTTATAAGGAAAGTTAAAGTTATCTCTATTGCTACCAACAACATAAACTTTTCCATTAAATTCACTTCTAATTGCTAAAATACCTGCTGCATATCCTTCTTTATTAAGATAATGTTGTCTAATTTTTTTGTTGACTGCAGTGACATCGCCTTGATTTTGATACAAATCTGTGATCAGAACTAAAAGTTCTTTTCCTTCCTTTTGTGGTGCAATAGCACCTGTTAGATTACTTGTGACTCGATCTTCGTAGTAAAACCTCTCTTTTATTGCTTCTAGGAATTTTGAACGACTGATTTTTTGTTTCTCCGGCCCTCCAACACGATAGTATTCAACTAAGTCAGATATAGAAAATGTGCGGTCTAGCAGTTGTATTGTTTTTATATAACGACTAGCACCGTTAGTTAAATATCCCGGCATAGATTCTGAGCCATCTATATTAAGGCTAATATTAATTGGGCCTGGTGGGGCATCCAATGAGGGAGACTGACCTTTCGTCAAAGGTACATCACAAGATAGATCGTTGTAAGTTTTTGGTCTACAGGCTGTTGTGATACCTATTAGCATGAATAATAGAAGGGGAATTTTCCATCTTGTAATTTTTGTTGAATTCATAATAAGTTACTTAATTTATTTTATTAATTTTCAAAGAATATAATACAGCAGTTTTTATTTGAGTAAAGCAGATTAGGAAAGCTTTATAGAAAGTCCTTACGAGGTTTTGATTTTGACGTGAGGTCATCAATACTGAAAAGCTCTCTAATACGTTTTCACAGAAATCATTTGACTTTCTTTAATTCTGACTTTTGACTTTTGACTTTTGACTTTTAACTTTCTTTTGTCTGATTTTCATTTTCAGAGTTATCCTCATCTTTTAACTTCCTAGATTCAAATTTTAATACTCCCAATTCTAAAACTTTCCACTTACCTCTATCTTCTGTAGGTTCGACTTTTGCTAGCTTCAGTAATTGAAACTTCTTCAACTCCCCTGACGAATCTCCATAACATTCAAATAAACCTTGTACATCTTCATTATTATCTGGGTTAATGTTGGCCTTCTGTCTGGGAGCTAAATAGTCACCGCTTTCCTCCGATAATATCCAGTAATTTCCGAATCTCTTTTTTTCCAAAATAACTGTATTGCTACTATCATTGACTTTTGCAACAGTTGTAGGTTTTTTCGAGCGCCAGCTCTGACTGCTATTGTAAAGCTCTACAAAATTAGCTTCTTCAGGTGGTAGCGGTGGCAGAATTCTTGTTGGTTCTGGTGTTGGTTCTGGTGTTGGTTCTGGTGTTGGTTCTGGTGTTGGTTCTGGTGTTGTTTCTGGTGTTGGTTCTGGTGTTGGTTCTGGCGTTCGTTCTGGTGTTGGTTCTGGTGTTGGTGTTGGAGTATCTGAGGATGACATTTTTATCTGTATCCACTTAACTATACCAGGCTCGGACAACTGCCAACTTTTACCTAAATTAATTGGAGATACTTTAGCGGGTTTTAGGAGTAATAGTTTACTAGAGTCTTCCTGGAAACTGGAAGATTCAAATAATCTAGTAAACATTTGTTTATTAAATTGATTAAGTTTGATATGTTGTTTAGGAATTAGATAGTTGTCACTTTCTTGGGATATTATCCAATAATTTCCCCGGCGGTTAGTTTCAAATACTACTTCCTGAATGGATTGATTCATACTTGCTTCTGTTTCTGAGACTGTTATTGCTATTTCTAATAATGAATCTGGACTTGCATTATAAGTTGCTGCTAACTCAGCTTCTTGCCAACTTAGATTGAGACCTATTGGCGATGGGGGTGGTGATATTTCTTTTGGGGAGGAAGATTGTTTAATGTTATCTAGCCTTTCTGTTAAGGAACTAACTTGTTGAGAAATTATTTCTAAGAGTTCGTCTTGACTACTCTCTTGAGACAATTTTTTCCAACACTTTTGCAAATTTGTTTCTATGGTTGATAACTGAGATTGAATACGCACTCCTACTTGCTCGTTCAAATTTTCCAATATTTCTAGCAACCCAGACTCTAGATTTTCTGCAGGATAGATTTGTTGGGATAATTGTTCTAAAACCTTCTGCAAATTTGTTTCTATGATCAACAACTTAGATTTTTGAACCTCCTGTTCTTGATTTCCCGCTACAACTTGCTTAGTTAAATTATTCAACTTTTCTGCTATTTCTGGCGATCGCTCTTTTTGAGACTCCTGTAATTCTGTTTCCAGTTGATTGTGCTTTTCTGTGTAATCATCCAATTTTGATTTCATCTCCCTTCCCTCTTGTTGAGATTCCTGAAATTCTGTTTGCAGTTGATTGTACTTTTCTGTATAATCATTTAATTCTGATTTCATCTCCCTTCCCTCTTGTTGAGATTCCTGAAATTCTGTTTCCAGTTGATTGTACTTTTCTGTATAATCATTTAATTCTGATTTCATCTCCCTTCCCTCTTGTTGAGATTCCTGAAATTCTGCTTGCAGTTGATTGTACTTTTCTGTATAATCATTTAATTCTGATTTCATCTCCCTTCCCTCTTGTTGAGATTGCTGAAATTATGTTTGCAGTTGATTGTACTTTTCTGTGTAATCATCTAATTCTGATTTCAATCGCGATCGCTCTTGTTGAGATTGCTGAAGTTCTGCTTGTAACTCTTCATATTTGGCCCTCAATTGTTTTAGCTGAGATTCCTGTTTCTTTAGAACGTGCAACTTTTGTATCGCCCACTTTTCTACTTTTTGAAGAGCGTCGGACGAACTAAACCCCGAACCTTCAAGAACTTCATCGCCACTATTGGAATAAAGCCTTAAATACCAACCGCATTTGAGACAAAAATTCACCTGTTGCTGTTGATATTCTGTATTGCAAACCGGACAATTTGGCATTAGTTATCTTTCCATTTATAAATTTACTTCAATCTACAAACCACTGTTCCTCTTTACTCAGATATAATACATCTTCTCATTTTCCCTCTCGTTTTGTGGTAGTAGCTGGTTCTATAGATATGTGAAACTTTACTTGCGGGTCTATCGTTGTAGTCGATGCAGATATTATGGACTATTTCGTAGCCATCCTCCAAACAGACTAACAAGCTCTTTGATTGGCCTCAACTCTCCTTCCAGCAGTCTTTGCAACTCCTCTTTGAGTTTTAATATTTGACTATTAATTTTGTTAATTTCTGCTCCTACCGCTTTTAAATAAGTAGTATTGTTTTTCTGCTTATGAGTTATTTCTTGCAACTGATAGATGTTATTAATTTCACTTTCTTCTAGTTTTGATAATTGAGACTGCAACTGCACCAACTTCTCACTTAACTCAGACTTCAATTGTGCCAACCTCTGAAAATAATCGGCCTCCAAATTAGAACATCGTTGCTCCTGGAGCGCCCCTGCCTGTTCCAACCGTTCTAAACGCTCCGTCAAATTACTCCGCCAGCGATCGCCTTCCTCCAACTTGGCCAAAGTCTTCTGTAAGCGATCGTAAGCCAACTCTGCCACCTGAGAAGCAAAGCGATCGCGCTCGTCCCTGGCCAACCTCAACTCAGATTCCAGTTTTTCTCGCTCCTCCTTTACTCCTTCCAGTTCCGACTGTAGCCGAGATAATTGAGAATTACCACCAAAATCTAACACCCCCCGCTCCTCCAACCGCCACTGATCTCCCCCTGGCGTCAGAGAAACCTTAGCCAGTTTAACCAGGATAAACTCCCGCGCATCCTCTGAAAGAGAACCATTGAACTTGAACAAAGATTTAACAGTATCCTTGTTAAAAGAATTAATTCGGAAATTTGCTTTAGGTAATAACCAGTAACATCCCTTCTCCGTAACCATTACCCAATAATTCCCATTTCGCTCTTCACCGAGCAAAACTTCTGAATTAGAATATCTCCATCCCCTAAAGTCAATTTTTGAAACCTTAATAGCCTTTCTTGAGAGAACCCTCGGCGCATAATTATAAGCTTCGATCAATTCATCTTCAGACAAACTTATCCAACCCCGTGGGAGAGTTTCCAGGGTTTTCGTCACCCGCACCGAGTTAGTTAATTCTGAGGAATAATTATCTGGTTTCATTGTTTTTTTATGATATATAGCCTTTTTTACTGGTCAAATATTATCGAGTTTATTTAACGAAATTTCAATATATTTTACTACCTATTAATCAAATTGTAGTATACCACGTTCGACAAGCTGCCAAGTTTCACCTTTTGAAATAGCAGATACTTTGGCGGGTTTTATTAGTTGAAACCCGGAGTATTCAGGTCGGTATCCCTGACATTCAAATAAATTTGCAACTGTCTTACTGTTATATTCATTAATTTTGATGTTATGCCTAGGAACCATGTAATCAATATCAGCCTCATTTAGTATCCAATAGTTTCCTCTGCGAACTTTCTGAATAATTACTGCTTGAGTGCTACTTATACGAGGTTGAACCATGCTTCGGTCTGCTTCTGAGACCTCTATAGCATTTTCTGATAAAGAACGGGTATCTTCTTTATATATTAACATAAACTCAAGATTGGGCAAACCTCCAGCTATATTATCTGGAGTCTTTAGTTGCTGATTTTGTTGGGGCTGGTTTATTTGATTTGGTAGGTTCCTTAATTCAATATCCAATCTTTTACGAATTTCTTGTTGTAATTGCCCATGAATTTCCTCTTTCACTGCTTCAAAAATCAGCTTTTTATTATCGGCATTGTTGTCTGAAGTCTTTAGTTGCTGATTTTGTTGGAGCTGGTTTATTTGATTTTGTAGGTTCCTTAATTTAATATCCCATCTTTGATCAATTTCTTGTTGTAATTGCCTATAAATCTCCCCTATTTTATCATTTACTACTTGAACAATCAACTTTTTATTATCGACATTATTACCTGGAGTCTTGACTTGCTGATTTTGTTGTAAATAGTATATTTGACTTTTTATTTTTTTCGTTTCAGCATCCCATAATTTAGACATTTTTTCTAATTTATAATAAGCATCTTCTACTTTATAGTCTACTTCATAAACAAGTTCTTGAGTATCTAAATTACTGGGTTTATTAACAGCATTATTCTGTTTTATCTGCCATATTAATAGCGAAATATAAAACAACAATAAGACTGTGAATAGTACTAATAGAATGAAAGAAAATATCACTGTTCTTCGTATATTCTTAAACTGATTTAATTGATTAAAAATTGCTTGTTTTTCATAGTTTAAATTCTTAATTTCTTCCTCATTGTTATTAGCTATAGCGGCTAATTCATTGTTTGTTTTTTGAACATCATCAAAGCTGTTCTTTAAATTTTCCTGATCTGGATTTAAAGGAATTGATGTTGTCGAAGTACTAGGTGGTATTTCTGGCTCTAGTTGTACACAAGCCACGAAAGAACCAGATATTAATACCAAAGACAGCAATAAACTGTATGTGCTTTTCCAACTGTGTATGCTTTTCCACATAAAAACTCACTTTTTTCTTCAAAATACATCCCCATAATAAGGTTTGTAAACCCTTATAGCACTGTTCCAAAATTAGTATTTTGGGAGAAGTCTAATAAACGAACTAATAAACTATCGTATCCTTTTCACTGCGCAATTATCTAACTGAGAATTGACTTCCCCAAAAGGTTCCATTGCCCATTAATAAAATTGCAGTACTCCAAGTTCTACAAGCTGCCAAGTTTCACCTCTGGAAATAGCAGACACTCTCGCTGGTTTTATCAGTTGAAACCCGGAGTATCCAGACCTATATCCCTGACATTCAAATAAATTTTTAACTGTTTCCAAGCTATGCTCGTTAATCTTGATGTTATTTTTAGGAACCATGTAATCAACCCCACCCTCGTTTAATATACAATAGTTTCCCCTGCGAACTTTCTGAAGAATTGCTCCTTGACCGCCACCGAGACGACGTTGGTCAATGCTTTGTTCTGTTTCCGAGACCTCTATAGCATTTTTTAACAAAGAACGGGCGTCGTGCTGATACATTGATATCAATTGCAGATCTGACGACCCAAAATATTGATGGGTAGGTATTTGTGGGTTCATTTGAGGTACTGGTGTTACTTGGCTAGTTAAATGATTGGTTGTTATTCGAGATTCTCTGTGAACTCCAGCTACATTGTCTGAAGTCCTTAGTTTCTGATTTTGTTGGAGCTGGTTTATTTGATTTTGTAGGTTCCTTGATTCAATATCCCATCTTTGATCAATTTCTTGTTGTAATTGCCTATAAATCTCCCCTATTTTCTCATTTACTACTTGAACAATCAACTTTCTATTATCGACATTATTACCTGGAGTCTTGACTTGCTGATTTTGTTGGAGATAGTATATTTGACTTTGTATTTTTTTCGCTTCATTCTCCCAGATTTTAGACATTTTTTCTAATTTATCATAAGCATCTTCTACTTTATCGTCTACTTCATAAACAAGTTCTTGAGTATCTAAATCACCAGTTTGATTAACACCATTATTCGGTTGTTTGGTATTTGTATAAGCTTTGTTATATCTTTTCAAAAGCAGCTTTATTCTCCTCCAATCTTGCCAAATATAAACACATAAACCACTTAAAAATACAGCTATTACCAGCACTATTATGACAACAAATGTCTCTAATTTTAGTCTACTTTGAAACTGATTTAATTGATTATAAATTTCTTGTTTTTCAGAGTTTAAATTCTTAATTTCTTCCTCATTCTTCTTAGCTATAGCGGCTAATTCATTATTTCTTGCTTCCAAATCAGCTATTTTTCTAGCCAATTCTTTGTCATCATCTTTATCGAGGGTAACAGATGAAGGTAAACCAGTAACTTGACCAAGATCGATAATTTTAGCTTTTAGCTGTTTGCTGTTTTCTGTCAATGACTCATTTATTTTACTTTGCGTATCTGGACCTAAGCGTCCAAAATAAGATACTTCCGGATTTGTAATAATCTGCAAATTTAGTTGGACTTCACCAATTTTGTCTTTGCCTAATCCACCTTTTAATTTTTCAGTTATTTCTTTAATGTTACTAATATTTTGATTTATGCTATTAAAATTTTGCTCTAAATTTTCTTGATTTCTTATTTGCGAAATTTGATTTTTATACGTATTAACTTTTTCTTCCAGTTGTATTAGTTTTTCATTAACCTTAGAACTATTTACTGATTCCCTATTTTTGGAACCCTCTCTTACTGCAGCAATGTCCTTAATAAAATCGTCTAATAATGTTTGAAATTCATCGTTTGTTTTTTGAATATCATCAAAGCTGTTCTTTAAATTTTCCTGATCTAAATTTCCCTGATCTGGATTTAAAGGACTTGATGTTATCGAAGGACTAGTAAGTATTGTGTTTGGATCTGTTTGTACACAAGCCACTAAAGAACCAGACATTAATACCAAAGACAGCAATAAACTGTATGTGCTTTTCCAACTATATATGCTTTTCCACATGATAACTAACCTCTTAGTTCAATAAATTAACCAATAAATTCCAGTTTCCCTGGCTCGGACAGTTGCCACTTTTCTTCTCCAATAGAAGAAACTTTAGCAGGCTTTAATAGTTCAAATTTACCCTTAGATCCTTCACTATTGACACCTTGACACTCAAACAAATTTTTCAGAGTATCGATGCTATATTCATTAATCTTTATTGTATCGCTAGGAACTAAATACTGCGAACTACCTTGTTTTAATATCCAATAGTTGCCCCGGCGCTTTTTTTCCAGAACTGATTTACCAATACCTAAACGACTGTTATCAATACTCTCTGTTGCTGCTGAAACAGTTATCGCATTTTGTGATAAAACAGTACGTTTTTCTTCGTCCTTGTAGTCTTTTAACAACTGTTCTTCTTCACTCAGAGGTAATTGATATTTTCCTTCCTCCTCTACTTCTCTGGTGGTATTTAGTTCTGTAGATGTTTGCAACTTTACTTGCGGGTCTATCGTTGTGCTCAATGGCAGATATTCTGGATTATTTTTGAACCATTCTCCAAACAAACTAATCAACTTTTTGATAGGCCTCAACTCATCTTGGAGTTTTGAGATCTCATTATTAATTTGGTTAATTTCTTCTCTTCCTGCCTCTAAAGAAGCAGTATTGTTGTTCTGCTTCTGAATTAGTTCTTGCAACTCCTCTTGGAGTTTTGAGTTCTCATTATTAATTTGGTTAATTTCTTCTCTTTCTGCCTCTAAAGAAGCAGTATTGTTGTTCTGCTTCTGAGTTAGTTCTTGCAATTGAGATTTGAACGATTCTAACATTTGAACCAATTGCTCTTTTATGTTATGCTCCCAAGTTGCAGCATGTGCTGATGTTTCTCTAATATTTTCAAACCCTTGAGGTTTATCGCCAGTTAAACTATCATGCAGAGCATAACCACAATTCCGACAAAAATTATCGCCCTTGTTTACTTCAGCCTGGCACTGTGGACAGTTACTCATATTTCCTACTAAGCTCCTTAACTTCTCTAAAATGGTATATTGTGACGAATTATTAAATCATTTTTACAGCTAGTCATTAAAGCTATCTAACACACCCTACTAGACCAACAAATCTCAAATTGTGCATGACTACGGATTAATAAATCCCTTTTTTAGTATGAATTTAAGCCCTCTAAAGCACCCTAAAAGTTTTGCTACAATAGCCCAAATTAAGCAAATTAATATGATTGCAGATTCAGACATATCTAGTAGTATCCCTAGCAGCCTAATTTCTGGCTGCCAGTATTGAGATTCTAGTCAGAATTAGACCACCTACTTACCTGCCCACTCCTTAGCTAAAACATGTAATAAAGCCTTCAGCCCCATAATAAAAGGCGGTTCCACACGAATATCATCCGTTTCTCCCTTCATATTCAACAAAACATTTGTCAACTCCCTCTGGGTATTTCGCCAAAGAGTCTGGTTATAAGTAGATTCTGGTTCTGCCCCTGGCTCGTTCCCCAGTTCATAATCCTGTAGCGGGAGAATTTCCTCAATCTCCAACTCCTTCAAAGATACATGAAAATCATCTAGAAACGTTCTTAACTGTACTAAATCAGGAATTTTTAACTCCCGAATATTTCCCTCAAACTCCAAGCGTTCTCTCCAGTTGATGGGATTACCATTAATTTCACAATCCTCTCCTGCAATCAACGGATCTTTAGTTTTCCTCCCTAATCCTGTCAACTTAGTACGACCCAAGACCAAACCACAAGCTACCTCGTCTTTTGGTCTCTGACTCAATCTCGTTTTTTCCAATATGCGATCATCAAATCCAGAGCCTTTAGTCAACATCTGACTCAGCAGCTCGTTAACTTCCGAAGAAGGAAGAAATTTACCCCTTTCAGCTAACCAGTTTAACAATCGAGAACCATTTCCGCCAATATAAACAGGAGTAATTTCGCGACTCTTGTATTTTTCCTCTTGTTCAAGAACTCCCAAGATTGTCCCCACATAGTAATACAATCCCCCCATACCAATTGCCATCAGCCGGAGCAAACCTTGAAACTTCGGATCGTCCTCTGCAAAATCCCTTTTATTCTTCAGCCACTTTTCACTTTCCAGGCGTAGAAATACATCCAGCTTGGCACTAAACTTGTCTTCAGTTAATCGATCCCAGTCTTTCAAATTCTGCTCGAATAGCTGGGAGAAAAAATTTGGATTCAATTCTAAAAAATTCGACAACAAATGACGACCAGCCAATAAAACCGAACATTGATGAATGAGCTCGTTGTTGTACCAAACCGAAATATCTGAAGTTCCACCTCCCATATCAATACAAGTTGTTCGGATTAAATCATGTCTTTCCTGGTCTGCAAAATATTGAGCGATCGCCAAACTCTCAGTTTTGAATAAACCTACATCATCTGACTGCGGGCAAATGTGTGTAATTCCAGTTTGAGCTTGAAGTTCCTCCGTCAAATCTTGCTAAGTCTTCGCATACCTATTTTTATCACGACGAGAAAAAGCCGTAGGATAGGAAATACACCACTGAATTTGTTTGACTCCTTCCTTGGCGGCAACCGCGCTTACATGTAAGGCTAAATGTTTCAAAAACAATTTGTTAGGATGGTAATTTTTCCACTTCAAGTCTGTTTCTATCCATCCCCTGAGCGGTTCAAACCTGTTGCGATCAGGAATATATATCCTGCCATCAATAATTGGGAAATCTAGGTTTTCCGTCTTATTTGGCTTCCCCCTAGTTGTCAGCACGCTAGACAAGGGTAACGGTTTGTCAGTCGGGATAAAGCTTTCCGGGACAAAGTATTCAAACAATACAGGCCTGCGGGTTTCTGTCAAAACCTCCGTCACCTTCAAGTGCAAATTTTCCAACTTCAATGGCTCCGATAAACCGTTACTATTGACATAGATATTGGTGAAAGAAGTGCCGAAATCTACCCCCACTTTCCATCGTTCTCCCAGCCTAATTTTCTCTGGACTTTTCAGCAGAATCAAGCCAATGGGACTTCCAGAACTATCCTGACACTCAATGAAACTAGGAAATTCTTCTAGGTGAGTTATTTGATAAGCACCCCTACCATCTATAAAAGGATGACGATCTTTCGCTTCCGGTAGAAACACTTGAAAAGTATCCTCTCCAAATTCAGCATCGTAATAAAAAGCATAATAAGAGCGCCATCCATCCGCCAGGAAATTAGGCCATACTTCCAATACCGGAACTTCCGGCAAAGCATTTTTATCTTCTATGGGATAATCTTTGGAAATCCGATAATTCTGAGGTTGCCGAGGGTCATCTTTCATCCCTGACAAAGGCAAGTCCAGGGTTACCCGCACTTGAGGTCCATCACTACTATTTATTTGAGCAAACTCGACCTTAGCGATTAAATCTTCCGGAGTAAAATAGTCGAGAAGTATAGGATTGATAGGTATCAGGGGCGTAATACTTTTACCCTGAAAAATTAACTTCGTCCCCGGAGGTAGGAAAGCTCCCGGTAGAGCATCTTCTTGGTCTACAAACCGAAATTCTTCCATAAATAAATCCTTGGACTCCTTCCACTCAACATCTGGCCAAGTAATTTTCTTTTCACGCAAGTCTTGTATTTGTAGGGAAGCCAGAGTTTGCTCCTCGTGTATCCAAATATCTTGAGGCGGTTTTCCCCAAGCTGAAGAAATGTTCTGGTCAATAATCAATAGAGGTTTTACCTGCCCCTTATTCTTACTAGGAACTAAGCGAACCCAAGAAGACTGAGCCTCAGCTTTCACCGGACGATTAATACCTTCCAACACCCCTCGATTAATGGCCACACCAAAAAACTGAGGATTATTGCTCAAACTCAGGCCCTGGTCCATTGGGCGAGGCCCCAAACTATTTTGGAAGTCATCTAGCAATCCGCCGATCGCATCAATTGCCTCTGCTTGGCCCTCATAGGAAGTATCGCCTAAAATTCCCCGCAAATTTTCTAACCAGCGCCAGAGGAGAGCCTTCTCGCTGACATTGAGATGTGGTTGAGGAGACTCCAACTGACCCGTCAGTTTGTTCCACCAAGGCAAGCCATTCCATTTTCCTTCTTCAGAGGGGGCCACTATAGTACTAGGAGTAGTAAGACCCACAAGTATACCATACCACAGAAATATATAAATGTCTTGCCAGGGATTTTTGGTTTCTAAGGCATACAGGGCATTAACTGGATCCGGTAGCAGTTCGTATAGAGAACGGGCGAAAGGATTTTGGTCTTTTTCTAGCCCCAAGTCTAAAAATTGAGCAGTTATGGGAAAGCGGCGTACTTCTGCCAAAGCAACCGCCGCCAACATCCCCTGCCACTGTTGGACCATTTTATCTCGGATGGGATAATAGGGATTATGTAAAGCCATCTCCATGGATAAGGGACGAGCCCACATAGTCGGTACAGAGCTAACACTTTTCATTTCTCCTGGAGCTTGATAATCCAGACTAGAGGCCACATCTTGAAAGGCTTTTGCTGGTTGTGCCTCCCATTTACCAGGAGTATCGCTGGATTTCACATCACTATCCCGCTTTAACTTGGGCAGGACTAAAACGTAACTTTTGTTGACTTGTGTTCCTGTCATATCAGTTATCAGTTATCAGTATCGACAGCTAAAGCCAGAGGCTTGAAATACCTATGACATTTTTTTCATCCCCTTCAAAAGGGAGGCTTGAAACCTGATTTTTTTGCCATAATTGATATCCTCCCCGTCCTAAAGTCCCGGGAGAACTTATACTGTGCCTAAGCTCAAGGACTGTTTGACGTTTTATACTTAGCATGCGCTCTGGGCTCCGTAGGTAGTTGCTAACTTAAGTTTTTCCTTAAATCCTAGAGGCCATATATACGGACTTAGCCAGTCCTATAGTCCCACCGGGTGGAGTAGCCTTAAGTCCATCCTTGAGTTTTTTCACCGTATCTCGGGATTTTTTGCCTTTATCGCGACTATCCCCAACTATCAGATTTGGCAGTTCATTTCCGGCCAATTTTTTGTTAGGGGGGAAAGCATCGGCTTGAAACAAAGCGATATTATCACCTTCGCACTGATGCAGAGAGTATAGCCAGCCCAAATAATCTTCACACCAATTATTAATTATTCCAATAGCTTCCTGTTGGTCAACATCAGAAAAGTCCGGTTTAGTCTCCCCAGATTTACTGCCAGTTTGGTAGAATTCCATCATCCAGGGAGCCAACCTTTGAAAGCGAGCATTTTTTTCCTTTTTCGCTTCTTCTAGTTCGGGAGCAATTTCTGCTAGCCATGTAAAAGCAAATCTGGTGGCATTCACTAACTCTGGTTGGACTTCTGCCTTGTCTGGGATATCGTCCCAGGAAATAGTCCCACTCTGCTGGCGAGTCATCAATATCACAGACCCTTTGGCTGTAGATGAATCTCGCCAAAAGTTACGCGCAGCCAATGCGGCGTATAGTTCTAGGAAATGGGGATCGTTGCGCTGACTATCTTTGCCGATACTAAAATTGACTCGGGATAAGTTTTGATTACCTAGGAGATAAACTTGGTCAAAGATTTCCTGACCTTGAGTGACGTAATAACGAAGGGCCGCTTCCGTGTTCAGTAAAAACTGCTCGGAGCGAGCGTAGACCCCATCTGGGTTTTCCCCGGGTGTTGGAGCAAAGCCAAAATAGGGGAGTACAAAGAGGCAACCAGTTTGAACCCGATCGCGTACTTTGATTTTCTTCAACTTATTATCGATCAGGCGGGCAATAGTCGGCAGTCCAGAAGCCCCGGTCCCCCCAAATATAGACCCACACAGAAAAATTTTTGCCTCTTTACCGCCACCGGTATCTCCCTGAATTTCCTCGATCAATCTTCCCCAAGGCTCTTGCTCCAACCTGTCCAAATCTACCTGACTCATCACCGCTGCACCAATGGCCGGTCTGCCCCTAAATCCTACATCTAAGTTAGCTTCCCGTTCTTCTTTAGTATAAAGGACATCGAATAAATGGGCCAAAGTAGGTTGTTTTTGCTTGATTGTGTTGTAGTTAAAAAATGTTCTCAGTTCTTTCTCTTGGGCAAAAGGCGACCAATGATCGAAAGATTCGATTTTGCTTTTCATCCACCCACAATCTTTTTTGTCCCCAGTAGGGATCAAATCATAAGTTTTTTTATAGAGACTGATACTAGTCCTAGCACGAGCCAGATTTCCATTAGTTTCATCTGCATCTACAAATAAAACCTTAATGGGCTCTTCAGTAAATAAGCCTATGGCAGCTAATTTAGCTACTGCTTCAACACATTTAGCCCCCGTTCCACCAATTCCAATCAGATAAAGTCCCATAATTATTCGCTAAAAAAACGACGCAAGTAAATTGAACCTGGGGGAACAAACTTTAAACTCCCAGGAGTAGTGGTTGCAGTTGGCAACCAAAAAAGTAATAAGATGTCCAACACAAAAAAGATAGTCAAAAACACAAGTGCATCATTACTACCTTGAAAAAAGCCTATGGCCCCACAAATACTCAATACCGGGACTTTAGCAAATTTCAAGCCCAAACAAACCCTAAACTCTCTTTATGAGCGGTAAATACGTCGATGTTTTCATCTAACCACTCAACAAAACGATAAGATATTGCGGTACGAAATGCTTCTAAAGTATCAGTAAACGTATTTAATGGTTTGTTAGCCCAACGCCTCTTATACCTCCTGTTAACTGATGCCAGATAATAAATGTATAAGCACAAAATACTAAAATAAAATGCCTTTTAAGGCTGATTTTATCTCTGACTTGATATTCTCTTAATCCTAACCATCCTTTGGCTTCCCTGTAGAAAACTTCCACCCAATTTCTTTGAGAATAAGTAGAATATATCCACTCAGGAGTTACATATTTGTCTTCTCTATTAGTGATATAATAGTTAATATCAGTGGCCTCAGAAAAACTTTTAGCATTCATAACGATAGCTATAGTTTTTTGACCTGACATCCTAGATATTTCTACTTCTAATGTAGCTACCCAAACTTCTCTAGCATTTTTTGTACTTAGTTGAACTAAGTTGAAAGCTTTCTGAGGTATACTTTCTGCCAGCTTGTCTAATCTAATTTCCTCTTTAATGTCATCTTGTTTTTTAATGATGACTTTTCGATTTTTAGCTAATCCTCCTATATAAGTTAAACTTCTTTTCTCTAGTTGATTTAAGAATGATGTATTGTTACCATAGCCAAATTTCAATTAACACAATTTCTGGTTGGTGTCCTCTGGACAAACATTGATCTACTAGAGACATTGCACTCGTCTGGTTTCTTGACAAATTCTGGGTCTTTTTTTCCTTTTGGAAAAGAATCAGCTTTCTGATACAAAGCTATGTCTAAAGGTAGACTTTTAACTCCATCATAAAGATGAGTTGTCACCACGACTACACCATTATCTGTTTTTCCTATTTCTCCTATATATTGCCGCCCTACTCCTGCAGTAAAATTACCACTTTTTCTGTGGCCTGAATCGTCTATAATTAAAGCAATAGGATCGAGAAGGTTTTGTTTGGCGACGTTCCCACATTACTTGAAGACGACGCTCATTCACAGCATCTACAGACCAATTTGCTCGAACTAGAAAATGCCGTAATTTGTGGTACGTGTGACCTACAGTGTTGTTGGCAATTTGAGACAAGTTTTTTCGATCGCTTTCTCAAGAGTAATCCTCCTATATATTCCCTAAACCCTGTTTTTTGGGCTTTTGTTTTAAAGACATTGTTAAAGCGATCGCACCATCGATGGAAACAAGAGGGCATGGCCACTGAAGTTGTTTCTTTCATCAAACTTTTCCCAGGCCAGTAATTAACGTAAAATACATATCAGGTATACATTATACCCTTTTTTTTACTATTTTTTCACTAAAGTCCCGATACGGGAAATAGCAAAAATATCCACCACACTACCACCCACTGGTCCACTTCTTTAGATCGGTGAGCTTTTGCGTTGGCGGTCATTAAATACCAAATTATAGTTGACAGTACCGATACTACAAAAACTATCATCCCGCCAGGGTTGTAATAATTATTTATCCAAGTCCCTACATCAATATCTGATATTCTTAGGATTCTGCTTCTATAAAAAAAAGGTTGTACTAGGAACATTACGATTAATCCTGTCAGGCTAAAAATAATGATCCGAATAATTTCCGATGCTTTTATTGAATCTCCTATCAGTTTTAACTATTTATGTTGCATTCCTCCAAGTAGATTGATCCTGGAGTTTAAATTGATCTCCATATTTTTTTGGTCATCCTCAACCACTATATTATTCTGGCTAATCACTTGACATCCTCCCGACCCGTCTCTACGGGACAGAGCTGGATTCCCTAATATCAAGTTATAGGATATTTGGTACTTCTCGCCTACCTGGCCTCTGAAATTAACTGCCTTCGAGTCTTAGGGTTACTTCACAGTTTATCGCAACTCCGACGCCGTCCCTAGACACTGGGAGTCCCCCAAGGAAAACATTTATACTTGCGTTTATGTCCCTGTCATGTTATTGAAAAGATTCTGGACATTTCTTCTCTTTAATAATCTTCAATAATAATAAAAAATAAAGTTAATTATTCTATAGAAATTATCAATTATTTTCCCCTACTTCCTACCCCGTAAAAACTTTGTATGGAACGTCTCTAACTCTATATTTTCTGGAGATGTCTAATATTCAAAGATAATTTTTCTACTACATGACTACGATGAGAAAAACCCTTATAACTAGGAATATATTGGTCAATTTTGATTAATTCCTGCCCGTACTATTGCGCTTTATATTCTAGTTGCATTACTAATATTAAGTCTGATTAATTATTCATAATAAAAATGCTCTTCTCACATCAATTTATCCCAATTTCCAACTCCCAATTCCTAATTCCCAATTCCCTAAAATTTTCCCACCGTGAGTATTCAAACAAAAATAATATAACCCATCCCTCAGCTGAGGGTGGGCTATAGTTTTTTACCATATTTTATACTGTTAAATTTTCAATTACAATTAATTGATTTTATCTAGATTACTTGGGTAGTCAATTTATGGGTATAGTCAAACCTTGAATATTTCAATTTTTGCCCGTATTATTGATACTTTTAGCTACAATTTTTGATAATTTTTGGAATCTTTAAGTCTTACTGATGAATGATTTTTAAGTTAACCTCAGTTTTTTGTGCAACTTGTTAATATTTTTTGGTTTAACAACTAATTGTCTCTCATCAGAATTTATAAAGTTATTAATCTTTGCTTTTACTAATATAAAAACAGTTAGTGATGATTCCTAAAAAATATCAACCACTAACTATTATGACATACTCTATCAAACTAATTTTGATAGATTTTAAACTATTAATTATTCATCAACTTTCAAGCCTTTGCACGAAAAACTTTCTGATTTAATTTCACCATTTTCTTGAGTTTGATGAATTTCTAATTCTGCTTCAGGAGTTGCTTCAAATAAGAAACGTTCTCCAGGAAAAACTGTACGCTCCCAATATTTGTTTTCTACACTACTAACTCTAGCGATCTGCATTTTACGAGTATTATTCCCATAGAAACAGAGAATCTTTTGGCTTTGCTGTTTTGGTAGTCTATCTAGTGCTATAGTCACAATATTTAAATTCCCTCTAAGTTTTTGCTGCCAATTAGCAACCCGACTGAATCTGATATCTTTAAGAGTGCCAATACTGTTATTATAAGCTAACAAATATTACTTAAGTATATTTTTAATTAACTTTTGTAAAACAAAATTAATTTAACTTAAGTTGTCCAGTATAAACCTAGTATTTTATAAGTATAAATGCCCATAATTTAGCATTTCATACTGATAGAATTACTAATCTTACTAAATAATGTTGATAAAACAGTATTAGAAAACAAAAAACCTTCAGGATCAGTCAATCTCAGATGTCCCTCTATCGGAAGTTTCTGGTTATCAGAGAAAGGGGTTGCTACACCTTTTTGATTGATAAACTCTACCCACCCTAACTTTTGATAGGGTTGTAGATAGATTAATAATTTTTCTACAGTTTTTTGACCAAACTGCTGGGATAATGTTAAGACATTTATCCCTTGTGCCAAGCGAAATCCTAACATCAGTGTTTCTAACAAAAAATCCTGATTTGATGCATTAATACCCTGACTTTCTAAACTATGATCTTGAAACGATAGCACCCATTGATAATATTTTTTCCGCGTACGCGGCCTGGTAAATCTTTGTCCTTCTAAATAGCTGGCTGCACCCATGCCAAAGCCATAATAAGGATGATTTTCCCAGTAAACTCGATTGTGGCTACACTGATAGCCTTGCTTGGCATAATTAGATATCTCATAATGTTCATATCCCGAAATTGATATCAGTTGCTGTGCAATTCGATACATTTCAGCTGCTGTTTCATCTGTAGGTAAAGGAGCATGACCTGGTTTATAGTAATGTCCAAAAGCTGTAACTTTTTCTAGTACAAGGTCATAGCTGGATATATGAGTTGGAGAAATAGCTATTCCACTTAACAAAGAAATTTGCCATTGTTCTAAAGTTTGGTGGGGCAGTCCTGAAATTAAATCAATACTGAAGTTAATAATTCCTGCTTGATGCAATGTATTTACTGCTTTGTAAATATCTGAGACATTGTGTAATCGCCCACAAACCTGTAATAAATCATCTTGAAATGCTTGTACTCCAAGGCTGACTCGATTTACTCCTAGGAATTTATATCCTTGCACTTGTTCTAAGTCAAAAGTTCCGGGGTCCATTTCTATAGAAATTTCAGCATTGGCCACAATTCCAAATTTTTGTTCTAGGGCATCTAAAATCCGACTTAATTGACCCACTGACAATAGGGAAGGAGTACCACCACCAAAAAAAATTGTTTTTAAGGGTTGATCAAAAGACTTTGTAGTGCTTATTTCCTGACAAATTACCTCTACATATTCTTGAATTGGAGAAAAATTATCACCTTTCTTACCATCACCTACTACAGAGATTGGGAAATCACAGTAATAGCATCGCCGTCGGCAGAAAGGGATATGGACATAAGCCGAACTGGGAATACAATAATTTCCGACTGGCCTTTTCACTATTAATTAATTGTATTAATATTTACAAATTTTATAATTATATAAAAATATTTTAAATAATTATAAATTTTATTATGGGTAGTAGTACGGTAAACCATAAAGGTAATATTTTTTAGGGAAAAAAATATTACTTAAATAAAAATAAAATAACGCTTAACATAATTAGCGGATAAAGTCAAGTTGCAGTTGCAAATCAAAAAAATCTTCTTCATCTTGCGTTCTCAACTCTGGTTTCCTTCCACCAAAGTGTAAGTATTCAAGAGGATTTGATATTATAAATTACTTTTATTTAGCCGTATTATTATGGTAATCCTGAGGGTATAAATTATTATATTTTATTAAAGTTAAATAATTTAATAGTAATTAAAAAAAATTGCTATAAATAAGTTTTAGGCAGTAGATTAACAAGTTAATTTTAATTTTTTTAATCTAGCTAAATAGCTTGGTATCGTGTGTTTTTAGCTATGGACTATATGAAAAACAGGGCGAGATGAAAAGGTTCAGAGTAACACAGATAAAATTAATATTATAGATACTACCTTACATTTCATAAATGCACTTACTAGAATTAGTCATTCTAGTAGCTTATTTATAACATTATTTAATTGATTAGTTATAACTATTTAACTACAATCCTAAATATAATTAGTAATATTCCATAAATTTTAATGATAAATTAAGTAAAAATAGTCACTTTTTTTTTGTTGTAAGATAGATTTTGTAGTTCAGGAGTAATTTGACAGGCAAGGCAGCATTATTAATTGTCGGCAAATTGATTCTGAGGTTAAAACCTAATAATAAAGAGAACCTTAAAGAATGGTATCTCAACTTTATAGATATAATATATGCAACATTGAGCTACCCAAAAATTATCCAAAAATCATGGTTCTTAATCATTATTTTATTGGTTAGTACCTCATTAGAGAAATACCTCTTATAAAACAAAAAACAAAACAAAAAACAAACTAAAAAAATGCTTGACGCACTTATTATTATTTCATTTGTATTTGCTGGAGCGGGAATAGGTTTCTATAGCATAGAACTACTTCCACCTAACGTATTGCTAGAAGTCACTAACATCGAAGGTTTACGTTCAGTATTATCTGCCTTCACTTCTTTAATTGGGTTTGTAGTGGGATTAGTATTTCAAACTACATATCGCCGAGTAGAAATTAAATTCAGACAAATGCCTGTAGACTTATTATTAACTCGGGCGATAGGATTAATAATTGGACTATTAGTGGCCAACTTAATGCTGGCGCCACTGTTTTTACTTCCTATTCCCGATGAGTTTAGTTTCATTAAACCTCTTGTGGCAGTTTTAGCTAGTGTGATGTTAGGTTTTACTGGAGTTAATGTTGCTGATACTCATGGTCGTGGTTTTTTACGATTAATTAATCCTAACAGTCTGGATGCAGTATTAGTAGCTGAAGGTACTCTCAAACCTTCTACTACTAAGATTTTGGATACTAGCTGTATTATTGATGGTAGAATAGAAAGTCTGTTGAAGACAGGTTTTTTGGAGGGTCAAATTCTGGTACCAAACTTTGTTTTACAGGAGTTACAGCTTATTGCTGATGCTTCTAATGATCAAAAAAGAGTCAGAGGTAGACGAGGGTTAGATATTTTAAATAGACTTAAAGAGCTTTATCCTTCTCAAATTCAAATCCATTTTGCAGACTATGAAGAAATTCCTACTGTGGATGCGAAGTTGGTTCGTTTTGCTCTGGAAATTAATGGTACTTTGTTGACGAATGATTACAATTTATCTAAGGTTGCTAGTTTACAAAAGGTTCCTGTTCTCAATATTAACGACTTGACTCAAGCAGTAAGACCAAGTTATTTGCCTGGTGATACTATTGAAATCAAAATTCGTAAGGAAGGTAAAGAACCTTCTCAGGGTATTGGCTATTTAGATGATGGTACAATGGTTGTTGTGGAGTCTGGTAGTGGATATGTTGGTGATGAGGTGCGGGTTATTGTGACCAGTTCTTTACAAACTTCTGCGGGTAGGATGATTTTTGCTCGTACTCAAGAGTCAGCGATCGCTTAATCAAATTAAAAGTTAAAACTCGTGCATTCAACAGTCAAAACTTAAAGCTTAAAAATTTGATCAAAGAGATCAGGCTATTAGTTAGGGTGAGGATCAGTTTAACCATTTTGCAACAACTTTTCAAAGATACAATAGCAACAATAGTAGGAGACCTACCTTGCTCCCCTCCCAACGAGGGGATGCTGGTGGGTAGGGACGTTATATAAGGAAGTCTCTACAACAGGTCAACAAATTAAGATTAATAAGGATCAAAGTATACCAATAAGTCCTGTCAGAGAGTATGTTCATCACTTAAATTTCTCAATTGTTATCTAAGTATAGTATTAATGCATGAGAATTGGCTTTATTAAGAATAAAGGAGAAACTAAACTGCCAAAACTTATCCAATTCCGGCGTGAGTAATTTTAGATAAGTTTAGTAGAAAACAATCTAAAAATGAAAAATCAACAGCTAATTATTTTTACTCGTTATCCGGAACCAGGAACAACAAAAACACGGTTAATTCCTGTTTTGGGGGCTAAAGGTGCCGCAAACCTTCAGTTTCATATGACTGAGACAACTGTCATAAAAGCTAAGAAGTTATCTAATATGATGGCATTGTTAGTTGAAGTTAGATTTGCTGGTGGCAATTTACAGTTAATGAAAAATTGGTTAGGAGTGGAGCTTAATTTAAAATATCAAAAACAGGGTACAGGTGATTTAGGTGAACGTATGGCAAGAGCTTTTGAATCTGCTTTTTATCAGGAGATGGAGTCTGTTGTAATTATTGGTACCGACTGCCCAAGCTTAACTGTGGATATTATGTTGGAAGCTTTTGCTAAATTAACTGAATATGATGTGATCATTGGTCCGGCAACTGATGGGGGTTATTATTTAATTGGCCTCAAAAAAATTATTCCTGAGTTGTTTCAAGGAATTAATTGGGGAACTTCTGAAGTATTGTCAAAAACTATGGCGATCGCTCAAAATCTTAATTTAGATATTCACTATTTACCTAAACTTTCTGATATTGACCGTCCAGAAGACCTGGAAAAATTACAATTTGAAATTCATCAGGACTTACGCAAAGATACTATATATAGTACATAATTTTGGTGATATTCACTATAGTTGTATAGGTTTATAGTCGCGACATTAAAACCTCTACTTTGTGGAGCGCAATTCCTTAGTTTTTTTTAAAAGCTCCAGTTATTAGAGTTAAATAAGTTTAATTTTAAGGGCAGGATATTTAAATCCGATGTCAGATAATTTGATAACAATTCCTGGCTATTCTTACTCAATACTTTTTCTGATTTTCCTACTCTATAAGTTAAAAAAAATCCAGAATAATACAATTTTGAAAGTATAATTTTACGAATAGTAAAGTATATAAAAAACAGACGGCAGATGTATAACTAAGAAAAAAAAATGATTGATGAATTCAAAGTGGTATTGAATATATTTTTTCTGACTTTAAAGTTAAATAAGTTTGATTTTAAGGGCTAATTTATAAAGTAAATCTTAAATTATCTAGTCTCTTAAGCGTCAGTTGGATTAATGGTCCATAAATCATTGCTTTACTTACATCTGAATAGACTTCGTAATCCTTACTTAAGCGTCTAAATCTATTTAACCTCCCATAAGTACGTTCAACAAATCTATCGTTTAGGCTATTGCTCAAAACTTTGTGAGGTTCCTTTGATCACTTCTACTCTGACACCATTGCGACAAATCTGTTTAACAATATTTTATTGCTTACAAAATATCTAAACGATATTTAATCACAACACTTAATTTAACTGAGACTAAACTTTTTTTAAATTATCTTTATGAATAAACTCTTAGCTTGCTTATCTTTGTTTTTTGACTATTGGTAGGTTATAATTTCCAAAAAATTAAATTTGTGAAGGATATTTTTATGGAACCTATTGAGTTTGCTTGAGTAGCGATCGCCATTCCCTTCTTGAACAAGTCTGTGGAAAATCTAAGAGAGAAGTTAGGGGAAAATGGAATTAAACAATAGACATCTCCAAAATAAAAAATAAGGTAAAATTATCAAAACCATTTATTTATAAAGTCTCCCAAATGAATCCAACTTTAGAATATATTTATAACCATCCAAAAGAAACAAAAAGAATTATTGGCATTACTTATGAACAGCTAATAAAATTAATAGCAAAGGCCCAAATAATAGAATCAGAGAAAAAGAAGGCGATCGCTAAAACAGAAAAAAGATTAATTAAAGCAGGTGGAGTCAGAAAAAAGAATTTAACAAAGGAGGAAGAAATAATTTTAACGTTATTTTATTTACATCAAATACCGACTTTTCAAACATTAGGAATTAACTTTGGTATAAGTGAATCAAGTGCTAATAATATTTTTCATTACTGGATAGATATTCTCAGAGAATTACTGCCAGCAAGTTTATTAGAACAAGTAAAAAAAAAAGAAAATGAATTGGAATGGGTAAAGGAGATATTAACAGAATTAGAATTAATTGTAGATAGTACAGAACAAAGTAGAGAAAGACCAAGTGAATATAAAGACCAAGAAAAATATAAAATATGAAAAAATAAAAATCATACTTTTAAAAATCAAATAATAACGACACCAAAAGGAACAGAAATAGTAGATGTAATAGTAGGAGAAAAAGGTCCAGTAAGTGATGTAAAAATATTAAGAAAACAACAGGATAAATTTGATAAAAAACAAAAATTTCAAGGAGATAAAGCTTATGAAGGAGTAGAAAGAACTACTACACCAAAAAAGAAACCAAGAAAAAAAGAAATGCCGCTAGAAATCAAAGAAGAAAATCAAGAAAAAGCCAGAAAGAGAATATTTGTAGAACATGTAATAAGATTAATTAAAATATTTGGAATTGCTAGAGAAAGATTCAGATTAAAAGATAATAATTATCAAAAAGTAATCTTAACAATATGTGGTTTAGTGCGACTAAGAATTGGATCTTTTATATTAGCATAAACCATCAAAAGCTGAGATAAAAAGAATAAATTAAAGTACAATAAATATTTGAATTAGTAACACAAAGTATCTCTGATGCCCATAAAACTGTACAAATTAACTATCTTCATAAGTAGCGATCGCACCACTAAAGATAGTTAGGATAAGCGTTTGAGTATTTTTGGAGATGTCTAATTAGCCAAGCTATGGAAAACTATTAGGGCTATGCCTGAAAATACTTTTATGGCTTTAAAACCTTCACAAGATGGTCTTTTTCCTGAAAATTTTGAAGTGGCTATTAAGGAAATAGAAAAAGTTGCTAATCAAAATTGAGAGCTTAAACAAGATATTATTGATGTAATTGCTTTTGCTGAAAAAGAACATTCAGAAGATGTGAAAAACCTGCAAGCTGAGTGTCTTTGTTGCATGAAAATAGCGAACGCAAACTTCCCGCCAGAGAAGTCAATTAGAATTCTACTTTGTAGCTTTTTGGTTGACAATTCTGTATCATGCGCTTAAGGATAGCACACTGTATAACTCTACTGCTTGAGTATCAAATTTTCGAGATCACTTCTGGGAAGATAACTTTGAGCCTAAACATTTTTGTTTCTGCTAAAGAACGTCGATGGTATCCACTCTCACGTTTCCATTTTTTACCTCCCACTCTATGAATTTCTCTAAATTGTCATCTCTTGAGGTTAATAACTTATAGCTGATAACTGAATGCTTACCTTTAATCTCTTTACGGTATCCAACAGCTAATAATTGAATTACCAAAATTAATAAGGCTGTATTCTTTCAGCAAATACAAAAAAAATATCAACTCTTATCAAGACTATCAAATATATCTAAAAAGTGTTTTTTTTAATAATTGGTAGTCCTGTATATGTAGTGATAAAATTACAGTGAAGCGATCGCTTCATTATAATGATTAATGAAATACCAAATAGCTCCTAGATGGGACCGAAGCTTTTTAGAAAAGGATAAAGTCTTTCTGACCAACCGAGAAATTCTTTGACGCAAAGTATTATTCAATCTTTCTATATAAGCTGTTAAACCTGAATATTCCCCACTGATTTATGTCTCTCTTCAGGAAAGACAAGCTCGTAAGCTGACCAAAAATCTGTATAACAAACTGCACACGGCCTTAAGACACCGTGGGTTAGAATTCCATAATCTATGCTGCCCCTTTTTCTCCTCTTTCCCCTAAGTAAAAACCCACAATTTCTTTAGTTTCTATATCAATCGCTAACCACAGCCATTGTTTATTATTTTTATTGCCTACAAATGACCACATTTCATCACATTGAATGGTGAGTTTACCTGTTTTTTTTTAGTACATTTAATAGAGCGTGAAACCTCAGCATACTTATTATTGACGTAATTCTGGAGCCATTTTTCTGACACGCCTGTTACACGGGTTATACCAGCTAAACTAATTTTTTCTCTATTTTAATTTATCAATAAGTTCTTTGGTTTCATTACTAATATAATCTCTTTGACTATTTTCGACAAATTGTCTCTGACAATTTTGACATTGATATTTTTGTTTTTTGTTGTGAATAGTCCCATTTTTGACAATATGATTACTGCCACAACTAGGACAGATTAATTTATGAATGGACATCTGAATTATATAGATTTTTTCTTATTACTGTCATAGATAATAGCATACTTTTTTCATGATAGTTGAGTTTAATTCTTGATAGTTTAATGACTGATTATTATGTAGCGATCGCCTAGATAAAAATTTTGAATTATTAAGCATAAAAAACTTAATGTTTTCAAGATTGATGTCAATAACTAATCATTTATATTGGCTTATCACTACATATACAGGACCACCTAATAATTAAATTCTCACATTCTGAAGCTTTATAAGCTGGTTATATAATTAATAATTATGCAAAAAATATGGCTAAGTTTAGATTTTTTACTGCATTTATAGTTGGTTTTTATGTCATTAATCGCTGTTTAATTGTTGAAAAATTACATCTATTATATCTGTTATACAGCCTCTAAAATTATAAAGTACTCGGAAGCGTTCGCAAACAAAATCATAAAATTATTAGATGATTTGTGGACTAATTGAATAAACTCTATCGATAAAAAATTTGTGTCTTGACATTCATATATTTAAAGGTAACATAGCTATATAACTAATCGCTAAGTGCTGTTAGCGCAGTATTTTAGACAAAATGGTTATATAAATTCCCTTACTAAAAAATTGATGAGCAGTATTTCGATTATTATTCCGGTGTTAAATGAAGTTGGGACGATCGCCCAAACTATTTCCACAGCTCAAACAGGAAAAAATGTAGAAATAATTGTAGTTGACGGTGGCAGTAATGATGGTACTATTGAAGTTGTTAAGTCTTTAAATATTAAACTTATTTATTCCCTCCCTGGTCGTAGTATTCAAATGAATTTTGGGGCAAAGTTAGCAACGGGAAATATTCTTTTGTTTCTTCATGGAGATACTTTTTTACCATTAAATTTTGACGAATTATTAAGAGAAATCATAGTTCAACCGAATATTATTGCAGGTGCGTTTGAATTAGGTATTAGAGGAAAAAAAAGAATTTTACGAATAGTCGAGAGCATAGTAAATTGGCGATCGCGTTATTTACAAATGCCTTATGGAGACCAAGGAATTTTTCTTTCGGCTCAAGTATTTGAACAAATTGGTTGCTTCCCAGAAATACCAATTATGGAAGATTTTGAGTTGATCCAAAAGTTAAGAAAAAGAGGACGAATTGGAATTATATCAAAACCAGTATTAACCTCTGATCGTCGGTGGCAAAAGTTGGGGATATTGAAAACGACTCTAATTAATCAAGTAATAATTATTGCTTACTTGCTTGGGTTGCCTCCAAAAACATTAGCACAATGGTATCGTAGTCATCTGAAGTAAGACTACCTGATTAAATATCAAAGTATTGACTGATATTGGCTAAAGTTTTTTTCTGTCTAAAAAAAAGTACCTGTATCAGATCTAAAACCCTCACATTTTCCACAAAATAATTGCAGAGGGCAGCAAGGGAAATATATCTGACTACCTCCTCCATAATTTAATTTATTCTGACTAACTGTAAGAAGGTTTATGCAACTTTCCTATCGGGACTTTAGCAAATTTCAAGCCCAAACAAACCCTAAACTCTCTTTATGAGCGGTAAATACGTCGATGTTTTCATCTAACCACTCAACAAAACGATAAGATATTGCGGTACGAAATGCTTCTAAAGTATCAGTAAACGTATTTAATGGTTTGTTAGCCCAACGCCTTCTTATACCTCCTGTTAACTGATGCCAGATAATAAATGTATAAGCACAAAATACTAAAATAAAATGCCTTTTAAGGCTGATTTTATCTCTGACTTGATATTCTCTTAATCCTAACCATCCTTTGGCTTCCCTGTAGAAAACTTCCACCCAATTTCTTTGAGAATAAGTAGAATATATCCACTCAGGAGTTACATATTTGTCTTCTCTATTAGTGATATAATAGTTAATATCAGTGGCCTCAGAAAAACTTTTAGCATTCATAACGATAGCTATAGTTTTTTGACCTGACATCCTAGATATTTCTACTTCTAATGTAGCTACCCAAACTTCTCTAGCATTTTTTGTACTTAGTTGAACTAAGTTGAAAGCTTTCTGAGGTATACTTTCTGCCAGCTTGTCTAATCTAATTTCCTCTTTAATGTCATCTTGTTTTTTAATGATGACTTTTCGATTTTTAGCTAATCCTCCTATATAAGTTAAACTTCTTTTCTCTAGTTGATTTAAGAATGATGTATTGTTACCATAGCCAAATTTCAATTAACACAATTTCTGGTTGGTGTCCTCTGGACAAACATTGATCTACTAGAGACATTGCACTCGTCTGGTTTCTTGACAAATTCTGGGTCTTTTTTTCCTTTTGGAAAAGAATCAGCTTTCTGATACAAAGCTATGTCTAAAGGTAGACTTTTAACTCCATCATAAAGATGAGTTGTCACCACGACTACACCATTATCTGTTTTTCCTATTTCTCCTATATATTGCCGCCCTACTCCTGCAGTAAAATTACCACTTTTTCTGTGGCCTGAATCGTCTATAATTAAAGCAATAGGATCGAGAAGGTTTTGTTTGGCGACGTTCCCACATTACTTGAAGACGACGCTCATTCACAGCATCTACAGACCAATTTGCTCGAACTAGAAAATGCCGTAATTTGTGGTACGTGTGACCTACAGTGTTGTTGGCAATTTGAGACAAGTTTTTTCGATCGCTTTCTCAAGAGTAATCCTCCTATATATTCCCTAAACCCTGTTTTTTGGGCTTTTGTTTTAAAGACATTGTTAAAGCGATCGCACCATCGATGGAAACAAGAGGGCATGGCCACTGAAGTTGTTTCTTTCATCAAACTTTTCCCAGGCCAGTAATTAACGTAAAATACATATCAGGTATACATTATACCCTTTTTTTTACTATTTTTTCACTAAAGTCCCGCTATCTACTCCCTCACTCCCTAACTCTCTCTCCACTGCTCCTTAAAAAGATTTAGAGAGCAAATTTCCATGTAGGAATACGGTATTTAAGAGTGAGCATGAAAAGAGGTGTTTCTAGTTAAAGTTAGAGTTCCCCTGAGTGATATGATCATGAGGGAGCAAATTTACCAGCTATATCCATAGAGAGAAAATTTTGGTAAAAAACTTCCAAGGCAGATGAAAGAGGTTTCCATTAATTTTGCTTCAGAACTTCAAGACTATAAATGACTCAAATACTGGATTTCATTTTTTGAGTTTTTTTTATACCACTAGCTTTACTTTTAAAACTAATTTTAGTTATACAAATTGTTAACCCCTAATTTGGGAAGTCAGTAGTCAGAAACTCACCAAAGTGCCCCTATACTCTTGCTGTAGTTAAATTTAAGAGGCGCGAGAATAATCATAATACTCAAAGTCATTTTCTAATATGAAACATAAGCAGAAACCTAGATAAAATTAACTTTTCTAAAGTTGAAGACCAATTTTGAGATTAAAATCCAGCAACCTCTTAGAATAAGATTTTGATATCTTCTAAAGATTTTTCAACTCTCACACCAGAGGAAAGAAGACATATGACACAAGCAACAGATTCAGGATTCGTTCAACCTTACAAAGGAGATCCTTTTGTAGGCCATTTATCCACTCCTATCAGTGATTCTGACTTTACCAGAGCATTTATCGGTAACTTGCCGATTTACCGTCCAGGTCTATCCCCAATTCTACGGGGTCTAGAAGTAGGTATGGCTCACGGTTATTTTATCGTTGGCCCTTGGACAAAACTCGGTCCATTACGAGATTCCGCAGTGGCTAACTTAGGTGGACTAATTTCTACGATCGCTCTAGTTTTAATTGCCACTATTTGTTTATCTGCTTATGGCCTAGTTTCTTTCCAAGGAAAAAGTCCTGAAGGAGCAGACCCATTAAAAACTTCTGAAGGTTGGAGTCAATTTACTGGTGGTTTTTTCATTGGTGCAATGGGTGGTGCCGTTGTGGCTTTCTTCCTACTAGAAAACTTTGAGCTTGTGGACTCCATTTTCCGAGGTTTATTTAACAGCTAAATACCTCATGTTAGTTATCAGTGATTAGTTATCAGTACCTCAGACTGAAACTAGAAACCTGAAAAACTGAAATTTATTTTTTAATCCCCTATTCAAGGGGAAATTTGATAGCTTGTTTTTCGGTAAAATTAGGCGATCGCTTAATTTGAAATTATGTAATTGAAGGAGAATTTGAAATGACTGGTTCTTATGCAGCATCTTACTTACCTTGGATTTTAATTCCTGTAGTTACTTGGTTAATGCCAATTATAGTTATGGGTTTATTGTTTGTCTATATTGAGAGCGATGCCTAGTTTATTAATTAGTTATCAGTTATTAGTGATCAGTAAACAGTCATCCGAGTGAAGCTAAAAACTTGATAATAAAAAATCTAATATTTTTGTTATTCCCTTAAAAGTTCCCCCTATCATTGCCAGACTACAGTAGGGAAATTTCATAGAGCATCAATAGGATGCTACGTTTATTCAAAATGTAGCATATAAAACCCAGAAAATTGAGGTAAGTATTTAAGGCTTGCTGATCAAATATGAAAGTATTAACTGATATTAGCTAAAGCTTTTTTGGGAAAAAAAATAGATTTTTTTTTAGTCGAAAACTCTTGCCCATGTTAGGATTTTGGGATAAAACAGCATAAATATCAAAGGACGAATATAGCCGAATACCCTTTCTATAAATTCCCTGTTTTTCCTAAATATAGGGACGCCCTTATGCAACGTCCCTACTTATTTCCGCTTGAAGGTTGGGCTTAAGGGTGATATCTCTACTTATTAAAAATATTTTTTCAACAAACCCTATTTAATCTCTCAAGATATCTGACACGAAATATGAGAGGATATCTAGATTAGACTAACTTATTAAAAGATGAAGACATATATTGAAGTTAAAAGCTACTGTTAATAGTTAGAAAGTTCTGGAAACTATGACAAAATATGTATGCCTAGGACTTAATTTGTTAAAAGTTAAGTTCAGAAAAAAAACTGGTACTCAAATTCAAAATGATATCTAGTAAGTTATACTCAAATTCAAAATGATATCTAGTAAGTTATTAGTGAAAAATAGAACAAATGTCGAGATAAAGTAATACAATAAGTTAGTTGGTACAGTGAAGTTATCATATAAATTATGAAAATATTTGTCTATCATACCCCAGAAGAAACTCCTACGGAAAATATGCCAGACTGCGCGATCGCAGTTGATGTCCTCAGAGCAACAACAACAATGGCTACAGCTATCTACGCAGGTGCAGAAGCAGTACAAGTATTTAGCGACATTGAAGAATTAATGACGGTCAGCGAAAAATGGTCTGCTGACAAACGTATTCGTGTTGGGGAACGAGGTGGTAAAAAAGTGGAAGGTTGTGATGAAGGCAACTCACCTTTAAACTTTACATCAGAAACAGTAAAAGGTAAACGCTTATTTATGACTACTACTAATGGCACCCGTTGTCTTAAGCGTATTCAAAATGCTAAGGTTGTTCTAGCTGCAGCTCTTGTTAACCGCCGCTCAGTAGTTGAATATCTGAAGGAAAATCAACCAGAAACAATTTGGATCTTAGGTTCCGGGTGGGAAGGTAGTTATTCCCTAGAAGATACAGTTTGTGCAGGAGCGATCGCTCATAGTCTACTTGCAGAAACTAACTCTCTGTCAGATGAAAATGTAGGTAACGATGAAGTATTTGGAGCTATGTCTCTCTATCTTCAGTGGCAGGATAAATTGCATGAACTAATGAACCACGCTAGTCATGGCCAACGTCTCCAACGCTTAGAATGTTATGAAGATTTGAAATATTGTTCTCAAATTGATATATTGGATGTTTTGCCTATGCAGAAAGAAATAGGAGTTTTGTCTTAGTTAATTAGTTGTGTCAAATTAATTATACATCTTTATATATAGGGCTTACGCAAGGGCACTATAATATAGCGTCTACTAATTTAGGCGTTGGCGGAGGATGGTGGCGGCAGCTATATCGCTTAAAAAAAATGTAGCGATCGCCTCAAAATAGATACCATAATTAAAATCAAGGTAAAAAGCAGCTATAAAATAAAAATTGCCCCGAATCTTATTGTGGGCTTTTTCAATTCTTGGCTCAAATAGTCTGAGAGTAATTCCTGTTTGACTTAATCAATAGTTTTTCCTATTTTCATTGCTAATCTTTTTAAGAAATTCTAGACTAACATAGCACAAGCCATGTGATTTTTTTGAATTTTACTAAGGTGACATTGACAAAATTCGATACCCGTTAATTGTTTAATTCTGCAGTGAAATTCTTCAATTTCCCATCTAGTTTGAGTCTCAAATTCTACAGCATCTACTGAAGATTGACTTAAGTCGTTAGTGACCACATATTCTGTTATGTAGGTGGAAACAGTCCCCCAGAATAGCTTGACCTTCTTATCCCTTGGAAAACCTTTAATTTTCATTATTTTACCTGATATTTTTTCTGATTTATTCCCACATAATTCTCCTATTTTTTTATATTTTTCTACTCCACCAGTATCATCTACTAGACGATTTATTTTTAAAGGACAGTAATATATTTTTCCCATATTATCTATTAATGCCATTAATCTTTGTGTTGCATACCAACTATCCATTAATACTGTCTTAAATAGTAATTTATTCTTTTTGACCACATTTAATATCATTTCTTCAACACTCTTCTATTTTGGTCTTTTTATTATTATCTGGAGCATAAATCCGATAAGCTATTATCCAAAATTGTTCAATAGTTGGATTAAAATATATACAGTTTACCATCCCAATACCACGAATTACTTTATGCTTATTACCACTGTACTGTTGCCTAACTAACTCAATTTTACTACCATATTCTTTGTTGAGCACTGTGTCATAAAAAATCAAATAACCTTCTGTGTTAGTGACAATTTATTCTTGAACATTTCGACCTAATTATTTGTAATCAAAATTTTCTATTTTTCAATAACGATTTATCGTATCATGGCTAATATTTTCTAGATAATTTGCCAAATTTGTGATAGTATAATTTGTATGAGAAATAAGTAAATATTGACAGTAATCAATATAGTTAAAATTCATATTTTTGGCTAAAATTAACTAACATAATTCTATAATAATTAGGGTGTTTTGGCAAAATTTATTTACAGTTAGTAATATTTATCATTATGAAAATTAACTTATAGAGCGTGTCTTTATATAAGTTATGATAATTTTGTCATTCAAGCGATCGCTTAAAAAATTATAGCGATTACCTGAATTAGTAGACGCTATATATAGTGCCTTTGCGTAAGTCCTGATATATATAATATAAACTAAATTCTTTCAACTCTTAAGACTGTCTATGAAACCAGCAAGCAAATATATAGAACTGCTGGGAAAAATGGCAACTATACTCAGAAAGTAACCCTGGGAGGAAAACTGCCAACACCTCTAGATATTATGGTAGAGGGTAGTACAAAAAAACAGCTTAAATCTAGTAAATCAAATTCACTGGATTTAGTAGAAGAAAGCAATTCATTAACTAATTCTTGTAATCAACAAAATATTAGGGACAAAAAACATAAAATATATCAAATAATTTGTGCTGATGTAGCTCATAGTTTGAAAGGAGAATTTCTAAATATTGGAGGTTCTAACGAATAAATTCGCTACTTATCTAATAACTCACCGGAAATTTTAGAGGAATGTGAACTAATTAAAAGAAGTCTTGAACATAGGCAGATTCGTCTACAAATGTTGATAGATTATCTGAATCTAGGTAAGCAAAAGATGAAACCTATTGACATTGAGAAACTAATAGGTGAGGTTGAGCTTTTGTCTAGGCACAGATTACCTTCAAATATAAAAATGGAAGTTAAGATACAGGAAAATTTGAAAGGTCGAACTATTCTAGGAAATTTTGATCAAATTAAGAGTGTATTGTTTGAACTGATTAGAAATTCTACAAAGGTATTACATAAACCAGATAGTAAAATCCAAATATTTGCAAGTTATGAAAATGATGGATTGATTACTTTATCTATTAAAGATAATGGCTCTAGTATTGAGGATGGTTTAAAAAAGAAACTGTTCAAAGAAATCGTAGATAGCGAAAGTGGTTCTGATATAGGATTGTATATCATTAACAGAATTATACATCAAATAGGAGGTGATTTAAAACTAACATCTTCGGAGGAAGGAACTACTATTACTCTTTTTTTTTCATGAGAGTTGAATTTATAAAATATATAAATTTGTAAGTTCAACTATAACATTTTTCCAAACTTTTATTTTATGGGTTTTAGAAATTATGGTATTGAGAATATTAATTGTAGACGATAATAGAGATACCCTCAAAAGATATATTAAGTCTTTAAAACGTAGAATCATATCTGAATTTTTTAATGTTGGTATAAAGCAGAATACAGAATCTAAATTCATCATAGAAGTAGAGGGATATGATGCAGTAATCACAGCACTTAAAAAATTAAGAAATTAACCATTTGAAATTCTCATTGTTGATTTAAGAATTCCAGGTTCATCTGGGCAATAAATGGGAGGATTAGAATTAATAGATGAGTCGGTATAGCTCGACTCACTTCGCCCTATTATTGTGATAACTGGCTCACGGGGTGACAAGCCAGTTGAAAGCTATATATATAAAGGGATTTGCCTTCAGGAGCTGAGGAATAATTCAATAAAAAAAAATCCTTATTGGACTGGGAAGGGGGTGTAGTGCGAGCGCAGAGCGCTCGCACTACACCCCCTAACTGGGTTGAATAATAATTCAAGTTGTGCAGTAGAATAATATCATGAAAAAACTTAACTTTATTAATTAATTTTTAATCAAAAATTACAGTCTAATTAACCACTTTATTCATCGCTTTTATTCCCCTGCGATAATATAGTAATTTATGAGGATTAAGGCTCATTAAATTTTCTACTAATTTCCACATTAAATCATCATTTATTGCCCAATAAACACTAGATAACCCTAAGCAAAAACTACTGTTTCTTCTTTCTTTTCTACCTCTTTCATTAGTTCTTGATATATATTCTTGAACTCCTTTATTTTTAATTTCTTGTCCTTTAAATGAACTAATTGTGTATGAAATAGCTATTAATAAAATTAGATTATTAAGTCTAGTTTCGTTGGCTTTTGCTGATTCTAGATTATAACCACCAGTTTTATAATCCTTAAACATGGCTTCTATGCCCATTCTCTGGCTATATATTTTTTTAACTTTTCCACATTACTATGATAAATTGGAGAGAGTATACCATTTCTCTGAAACAGAATTGTGACGATATTTCTGTCTTTTATATACAAGTAAATTATATGTTCCTACCTTCAAAATTTTGGTAATTTTTTGATTCAATAATAGTTGGGATTCACCGATATTTACTTTTAACTCTGAGAGTTGACAATATTTTCTCCCTCGTTTTATCATAGTTGATTTTTTTTGTCTCAAGACAAAATATACGTCTTTTTTTTTATATTCTTTCAACCAATGGCACAGGAAAATACTGTGGAATTCGAGGGTGCTGTGAGAATTATTTTGTGTACTTTCAATAATTTTAATACAGGGCGAATTACTGATTTTTGTTCGGTTAAATTACTAGCTCCTTTATGAGATAAAATCTTCCAATATATAGGTAAAGCTCTCTTTTTCCAAGCTACAGTTATCATTAAAATATTAATATTTTGCCACTGAGTGCGGTCTAAAATCAACACTAACTCTGAGGTAAAGTTGAAGAGATTTTTTACCATTATTTTGACTAAAGGGAACCAAAATATAGGTAAACTTAATTCCTTTAGGGTTAAAAATCTTTCGCATAAGTTTTCGCTTACTTTCTGATTTAATTGGTAGCTGAAAATAATTGGTTAGCTTTGATATTTGTACAGTTTTATGTACTGAAATTAAGTATAATAATATTTGTAATGTTACTACTTGAGATGGACTCAACTTTTGCTTAATATGGTCTTGATAAAAGCCTAATATATTCACTTTTTCTTCTTTTTTTTTTGTAATTATTAACCCTTTTTTATCATATTTTTAACAGTTTTTTTTAATGTTTTAATGAATAAATAATCAACCATGGGTAGGGGGTGTAGTGCGAGCGCAGAGCGCTCGCACTACACCCCTTCCCAGTCCAATAAGCGTTTTCTTTTTGTTGAAATATTCTTCAGTTCCCGAACACAAATTCCTTTCTATATATAGCTTTCAACTAGCTTGTCACCCCGTGAGGATAACTGGTTATGGAAATGTAGAATTAGCAAAGCGAACTTTAACTAAAGGTGTCTTTGATTTTATAGAGAAGTCTGCCACAGCAGTTGAAGATTTAGTGTCAGCAGTTCAAAGAGCCATAGATACTCGTAAAGAAAAAATAAGGCGAGTGGGAAACCCTTTTACACCAATGACAGGTTTAGAACCTACGGTTTTTGGTGGCAGATGGGAACAGGATTCAAAGTTGAGCGCAATAGGAAAAACCAGAAAATAATATCACCTAAAGCTTTTTTTAGAGACACTCTCACCAAACTATGGGAAGACATTGAAGATAAAACTGATGTATTTGTCATCCTTCTTGACGATCTAGAAAACTTGGCAGCAGTTTCAGATATTTTGATGACATTAAAGTCAGCACTATCCACAGAGTCACTGATGGAAACTAAAATTTTAGTTGGTTTGGCATCAACTTCCACAAGTTGGCTAGAAATAACATCTGTTCAAAAACATCATCCCCTCTCTAGATACTTTTTGAGTAGAGTAGAATTGACTTCGTTAACTGAAAAAGAGGTTCAAGAAACCATCCGAGAGTCTCTTGCAGGAACAGAAGTTTCATTCACTCAAGAAGTCATGCAGAATATATTTGAATATTCTAGCGGACATCCATTTGAGATGCAGCTACTGTGTTATCACCTTTTCAGTAATCATCTTTCAAGAATTGTAGAAATTGACATTTGGGAAAAAGCTTTACAAGCAACTGTGAGGGATGTGGGAAATGCTATTTTTGAAAAGTGGTGTTCTGACCTCAGTATTGATGAAGCAAAAGTTCTAAGGATACTCGCAGAAAATGAGAATTCTGTAGCACTAGAAAAGCTGGCAACTACTTTTGAGACGGAAAATCTGATGATCCCTCCAAATTATTCAGTTGAAGAAGTATTGAAAAGTCTTTTGCAGCGAAAGCTGATTAGTAGAGATATTTATGGTAATTATATCGTCAAAGATCTGATGTTTCGTACCTACCTCATTACTCATCTGAATTACAATAGCACTGGAAGCCACTGAAAGGAGTGTTAGAGAAGTTCAAAAGCTTTCCCCAAATTCAAAAGCAAGCTACGGGTTTTATAGGAATTTTCATGTTACAAATTGAAGTGCGGAATCTTGGTTCTAATGAATATATTCCCTGAGAATATGGTTTCGCTTTGGATCTTCTAACTTTCTCAATGCTTTAGCCTCTATTTGCCTAATTCTTTCCCGCGTTAAATTAAAAGTATCACCAATTTCTTTGAGGGTCTTTTCTTGACCATCATCCAAACCGAATCGCATTTGTAACACATTTCTTTCTCGTTCAGTTAGAGTTTTCAAAACACTTTCTACATCTTCTTGCAAGCAATTTTCAAAGACATATTTTGTTGGTGTTTCCCCATTAAATTTAATCATTTCCTTGTAGATAATGTTTTCCCCTTTATTTATAGGGTAGTCTAGAGATAAAGTTTCTTGAGCGCATTCTATAATAAATTGCAACTTCTCCGTTGTCATTTCCATGCGTGTAGCAACTTCTTCTGCAGTTAGGGGAGAACATTCTATTGAAATTTGCTTAACTATTTTCTTAATTTGGGAAATAGTTTCGTAGAGATAAACTGGCAACCGAACGATCCGAGAATAGTCACAAATAGCTCTGGTAATAGCTTGTCGAATCCACCAAATACCATAAGTAGAAAACTTATAACCTTTTGTATGATCAAATTTTTCTGTGGCACGAAGTAATCCTATAACTCCCTCTTGAATTAAATCTTGGAAGTCTAGACCACGGTTTTGGTATCGTTTGGCAACTGATGTCACCAGTCGCAAGTTAGCTGTCACCATTTGATTTTTAGCTCGTCTACCTTGCTCGAGGCGATCACACAGTTCCCATTTGCTCATTTTGGCTTCTGTTGCCCATTCTATTTCGTTAGGCGAACGGTTGAGCTTTTCCTCTAATTTTTCATAAATTTTCTCTAAAGCTAATAGCCCATCAATTTGATGTGCTAAATGAATTTCTTCCTCAGGGTGCAAGCGGGCGAAGCTATTAACTTGCTTATAATAAAGTTGAATTGAGTCTTCAGTAAATGTTCCAGTAGGCGGTTCTATGTCTGGGTCGTAGCTACCTTCACTATTATGTTTATTTGTCAATTCTTCTGTAGGTTCACAATTATTTATAGCTACATTTTCTAGCCAGTAAGTATCATAATAATTAGGATTTTGACAATCAATTAACCACCATTTAATTGAAATTTTAATATTTTGATTTTCTCTTCTATGAGGAGCAACTATTATTAACTTATTATATTTTTTTGTGGCAATTAGCAAGAAATTATTTTTGTTTCTCAAGATTCCCTGAGAAATAGTTATTATTCTTTCTTGCTCTTTATAATTTGTTTTAAATTTTTCTTGTCTTAATTCTAAAAGAAATACTTGTAATTCCTCTTGGTTCGGATTATAAATTTTATAAGTATTATCAATCGTTTCTCTGCAATAACTTGGTAGTTCTAGTTGTTCAATATCTAAATGTTCAATTTGGAAATTGAAGCCAAGTTTTTCAAACAAAGCTACTATCTTTTTCGGGCTACTAATTTTTTTTAGATCGTCTAGTTCTAATGTATGCCCTATCATTATCATCTATCTCCAAAATTAATTTATCTTAATATCTTTAGTCCTCATTGATGTCAATTCAAGGCATTATTTTTTCTGTTTTTTTCGATTAGTAGCAAACTTATAAGAAACATTTTACTTCTATTTACTTCTGTTTCCTGAATTATTCTGATAGGTTTTTATGGGAATCATCTTCTGCACCGCTATCGTAATCGTTTATTTTTCCCTAGTGACTCAAAGCTTCAAGTCAAGCAAAGCCTTACCTTTCTTCAACACAAGTAGTAATCACCAGATAAAAGTTTTAGCTATTACTACCATCAAAGAGCTTAATGAATCCATATATTTTATCATTATACCATATTTATTTTATGATGTCAAAAATGATGCTTCAAATTTTTATGTAATTATGTTTGCAGGTGATTTATTAAATAATATATCACTACCATATTTCAAATACTATGTCAAATATTTGTTGTGTTGACTTATATTTCAAGAAAAAATTTAGGCTCATTTCCCATCTCTGAGTCAGGTAGAAAATTATTTTGTGGCGCGGGAGTATTTAGACACATTGCAGAAAACGTCCGTAGGGATTAGTAATTGGAGTTTGGTGATTGAAAAGAAGAAAAACAATTAGGCCTGAGCAATATAGTAGCCGATCATAAATGGTTCGGACATTAGTTAATCCTGAAATTATCTCAATAATTACTTTTGAATGCATCACTTTTTCCTGAGCTAAAGCTATATTTTATAAACATTTTTTTTAGAATATAACATAGTTGAAAATATAGAAAAATTATATTGCAAAGAAATAGTTTTTTTTAAAGAAGCATATTTAAGAGACTGTTTTTCAAAAAAAAAACTAAAGATGGCCATGAAAAAGTATTGAAGGTAGGAAAATAAAAAAAACAATGATCACTGTCAAATAAATGTCGCGAAAATCTTTAGCCAAGGCTCTAAGCCCTCGCCAGTGGGAACTACTCGAATCTCTGCTACCGAAACCTCTACTCAACGAGGGCCAAAACCAAATGCTAATCTCATAGAAGTAGTAAATAGTATATTCTATATCCTTTACTCTGATTGTCATTGGCGTTCTTTGCCCCAGGATCTACCACCTTGGCAAACTGTGTCAACAAAATTTTCTAAATGCAACGGATATGTTGTTTGGGAACAAATCAATCATACTTTATGGCGAGAGACAAGAGTCCAATAAGCAAGACTTAATGGAGAACCTACTGCAGCCATTGTTGATTCTCGTAGGGTAAAAACAACAGCAAAAAGGGGGAAGTATATGGTTATGATGGTGGTAAAAAAGGAAAAAGTCTTAAGGGTCATATCTTAGTTGATACTCAAGAAATACTACTAAGAGTAGTGGTAAGTGAGGAAAATATCGGAGAACTCTTAGGGGCTATAGCCTTGGTCATGAAACAGGGTGAAAATATTCCAGAAACACTAATTATACCACTTATCAAAAAAAATGCTATGCTTCATACTGCTATCACATATATGTAAAAAAATTACTTATTCATATTAAAATTGTTAATTATACCTACTTTTTCTAAAGCCTCAATGATGAACTGCTATCCTGTTAATGAAGCTACAAAATCCTGGTTAATATTTAGCAGAATTTCCTTAAATTTTTTCTCAAAAGTCTGATAAATCTCCAATCTGATACAACTGCCCAATTACTTCTTTTTTTTGTATCCATATTCAAGAACTAATAACCTACCTGCTGGTAAAATTTTTTGAGTTATTCAATGTTTTCAAATTGTTGACTCGGTTCAGGATGTTCACCTATTGTTATAGGTTTTTGGGTCTAACCCTTGCGATAGTTATGCTGTGTTAACAGTTTGTCTACAACTGTAAAGTAAGAATTGAGATGAGATCGATTACTTCGGTAGTCATAAGTCTCTAACTTCTAAAAATATTAACTCACTTAACAAAAAATCAAACCATAGTAAAGTAATTATCTCAATGAGTCACAGCTCCTTCTAAATGCAGGAAAACTCAACCAGTTATCAAAAAAATAACTGGTGAAAATGCTGTTGACTCAACAAAAAGTAATGGAAAAACTACAACTTGAAATTGAGACATTAAAACTTAGTCGAGAAACTGATAGTAAAACTTTTTCTAAACCCCTATCAACAGACTTGCTGAAAAAAATCAGACAAAGCAAAATACTCTAAAGATACTGGAAGCTCTGAGGCAAAAAAGAAACTCCACCGGGGGCAACCAGGTCATCAGAGTAAAATACCTCAAGGATTTCTAAATTGAACAGAATTGAAATCCTAAAACCTTATGTATGTATGAATTGTAGTCAAACATATTTTTAAGATGAGCCAATTCAAGTAGAAACCCAACAAGTAGCACAACTGGTAGCTAAAACCATAGAAGTACTAGAGTACCAACGTCACAGGTGTCACTCTAAAAGCTGTAGTCAAGAGACATCTGCGGATTACTCTGCTCAGATGATATAATTAACTTGATTTAGGGCTCAAGCTACAAGCTTTCTTGCCGTAATTAGGTAATTATGGACATTTACCTGAGGAAAAACAACAAGAGATGTTATGGGAGTTGGGAAAAATTAAGATTGGGTTAGAGACTTTAGTTAATAAACTTCAAAGTTGTAGTTAATAAACTTCAAAAGTTGGAGTCAGCAATAAAACCTTATTTAGAACAATTATCAAATTGGGTAAAAACTGAACAACCAGCAATTCATATAGATGAAACGCCTTCGCTACTCAAAGGAATTAAGTAGTGACTATCGGTATTTACAAATAAAGATTTCTGTCTATTTAGAGCAACAGACACTAGAACCTATCCCACTAATAAAATGCAATGAATCCAAATTGTATAGTGGCGGGCGCTACAATTGCTTCAATACAAGCAGAAATACCCTCCTATCCTACAACTAGGCGACGATATTTACCTTGATCCCAGGCAAAACAACCCTCTTGTTGAAAACGAGACACAGAAACTTTGATTGCACTTCCTGGTTTCTTTTTCCTTTTCCCAAGTCGTTTGGGCATTTGAGGTTTAATCCCTCTTTGATACCTTGCTTGTCTTTGTCGTTGCATCATATCCTTTATCAGTAGCAATGACTTGAAAGCCCTTACGTGGCCGTCCTCTTTTGTAAGTTTTCAGACTAGTACTATCAATTTAGCAGAATTAGCTGTTCTCTTTCATTGCCATTAACAGGGGTAATATAGTTAACTACTGGTTATCCATTTCCTTGGCTCAAGGTATGAATTAAAATCTCCTTCCCTTTACGGCCGTAAGCTATATCCTCTCCTTCACCCTGACCAGGAAGAAAAAGCTTCATCTACAGCTGTGTAGCTCCAATTGATTAGTCCTTGGTTGTTTGCAATTTCTAAAATTCGTCTTTGTAGATGTTTGAGAGTTCCATCTTCTTCCCAATGCTTCAGGCATCTGTGTGCTGAACTCTTGGAAGCCCTAATCTCTCAAGCTGTTACATCCCACATTTTGTGCTTCATTATGTAGCACTAAAAGATACATGAATCATCATCAGAATTTAAGCCAACAAATTAAACATATTAATTCTATAGAACACAAAAAAATCAGTGGCATGAGTATTGTTTGCAAACCAGAGATTTCTTTTAGCAGGAGAAAGTACAGGAGCAACTATACTCCTATTGATAGCATCAATTAATTTTTGTAACCATTCAAAATGATTCAAGTGGTGTGAACATATGCGTTAGTGTGCGATCGCTTATTATTAAAATCACAGATAATATTTTTGATAACAAGAGGGTAAAAACTCTAAAATCAAGCTCCTTTTTTATGTGAGATTAACTACTTTTTGTAATTGATTAATTATTAACAAATTTACTCATTGAAAATATTAAAATATCCATCTTAATATCGGAGTATTTATCAACTTTCTTAACTAGTTTTTCACTTCACTATTGTTTTTTTTTAAGTCTTTCTCAGCTCTTTTTTACCAAAATTATACAATAATAAACACAGTAACATAATAAACAGTATTGTTTCTACTATTTCTGGTTTTTTGACAAAAAAACTATCGGCAAAAAATAGTTGAGCTTTGAGAACTCTGAAACCACGTTCACAACTCTGTTGGTTTTTATAATTCCAGAGTATTTCTGGGCTTTGAACTTCTGAATACGACATGGAGTATGAGGTATACCTTTACATTCTTTCTGGTGAAATAGGAAAAATATCTTCAAATAACTTCCATTCTATATCACTTAATCCTTCAAATATACCTGGTATCTTCTTTTAATTACCTATACTGAGTAACGCTTATCATAGCGTCACCATTTTACTATATTTTACTATTAGTAGGATAGATTTATGATGTTGCTTTCCCTGTAACTTGAACGATCTTAGAAAATATTGGGAAATCAAAAACTTGTGAAAGAATAGATTTGTTAGCTCAATTCTGAGATACTTTTCCCGATGCTCAAGAATTGTATCTTTGTAGTGATAGATAGTTTATCCCTCAAGAGTGGTTAACTTACTTAGGAATTGAACCTCAAATTCCTTTCCCCCTGAAGTAAAAAGCAGATCATAATATTGGTGATTACTCAAAAAGTTTAGCCACATCAATTATCTTTCCTAACCTTCAAATTGGGGAATATAAAACTATTTTAGGAAAACGATGGGTTTGGTGCAAACAAGTGTATTTTTCAGCTTTACGTTCAGATGATGGAGAATTACTAATTGTGATTAGCAATAATTCAGCTTTCACAGCGCTCGCATTTTATGCTAATTGATAGGGGTGTGAAATACTCTTCGGGATGTTTAAAACCAGAAAATTAAATTTGGAATCAACTCATCTAAATCAACTTAAAAGACTGAGTAAATTATTGGCGTTAATAAGTTGGGCTCTATGTTGGACAATTTTAATCGGGGAATGATTACATAAACAAAGACCCTTGAAAATCAAAAAATACGGTCCTAGGGCAAAAAGTATTTTTCGTTATGGACTGGATCATTTACCGGCGATAGTTCTTGACATTGATTTAAAACAAAATGAATTTATTAATTGTTTAAATTTTTTGTCTTGTACCTAGAATAAAAACATCTAAATGTCAAGCATAAAGATTTAAAATATGTTGATTATTATCAATCTTTTACAATTACTCAGACTAACTATACTATAACAAATTTAGCACTATCCAAATCGAAAATATTAACCATGATAGAATCAACCATTATTTAAGATGTGAATCTTTAAATTAACAATCTTTATAATGAAATATTAAAGTATAAATTTTCCCAAATACATCCACGTATCTAGTTTTTTATCACACAGTAATTTGCAAAAAGTATGGATATAACATTGAACTTAGACGACGACAATATAACGCCAGGGTATATATAGTCATTTAACTTAAGAGTGAGACATTAAAATCCACAATAATCACAGATTATTTCATCTAAGTCTGTATTTGAAAGAGCATACATTATGGCTCTCTTTAAGGCACTAAAATCATGTTCAATATCCTTCAAGTCAGGAAAATAATTAGGCATAAATATGACCTAAAGAGCTCCATATTCAAGTATTTATTTAATCACTATTTTTTGATGAATTGGTGCATGATTTATAATCCAAACTGATGTAATTTTCAATGATGGCAATCAACATATTCATAACCAGCCTTCCCAGTTTTCTACATTCAAACTTCCTATGAATATCATTGATGGAATTAAATCTTTTTTTCCTTTTTTTATACCAGGAACTAAGTTTTCTCTTTTTCCCCTTTTTCCTTGCCTATCTCCAGAAAATTTTCCCCTCTTTTTGACCACAAATAAAGACAATTTAGAAATTATTCAAATCCTGAATCCAAAAGAAATACTAAACTTTTAATCCCATATATTTTGATTAATTTCCATAAATCCTGATAAGATTTTATCCATTATTATCTACTTCTTTGCACCATAACATAGTTCTTTTTTTTCTGGTTATTTTCATTTTTTTGATAGACTTAAAAATTGCATTTGTACTTACACCGTAATTTTTTAGCTGTGTACTTTAATCTAGCTTCTGGATTTTCTGATTAATCTATTGACAATTCTCTTATATCTAGGGAACGCTAGAGATATTTTACCTTTGTTGCTACCAGTTCCTTTCTCTCAAGCCATCTGTAGATTGACCCTATTCCTATTCCAAAAACTTGCGCCGCTTTGCTGACTCTAACACCATTTTCTATTATTACTATTACTTTTTATCTTCAATCTAAACTATAAGCCATGATTTCTATTCCCATACTTTCTCTGTTCAATCTTATACTCTTTTTATTTCATTCTTAAGTTAAATGACTATATCCTTAACCTGAATTATTCATGAACAAAAAAACTAAAGGAAAAAAATAAAAATAAACATATTGATTAACGGTCGATAATCAAAATTAGTCAAATAACTTAAAATAACTTAAAAAAAAACTTAAAAATTTACAGTTATTTTTCTCAAAAAAACCCTAAAAACCTCAAAAATTTTCTTTTTAATTCTTTAATTATATGCTCCAAATTTGTAGTTATTTGAGCATAAAAACTATCATAAATTTATTGTTTTTTTTATCTCCATGTTTATGACTAAAAATTGAGAATTTATAATTTTCTATAGCCCATCTAATTTTATCAATACTTGATGAGGGTTATTCCAACTTTTTTATCAGCAATAAATATCATCAAATAAATGAAATTTTTGATTAGTTTGATAATAATTTAATCTGGCTTTATCTAATAAATAATTAATTTTATTCTGAACACTGCATTACTACTAAATCCAAAAACATATTGTACATTTTGATCTTCACACACTTTAATTATTTCTGGTAAAGAAAAGTATCGATCTCCTCTTAAAATAATCGAAACATTTTTTCATGCTTTTTTTTATTGCCAAAATCACCATCATAAAATTCCCTTTATTCCCTTGGCCGAATGAGAAGTTATTCCCCCTTCATTGTAATATTAAAGTAACACCAGTTTTTGCCTCATTAATTCAACAATAAAAATAGATTTTTTACCCATCAAAATCATGAAATAAACTTAGTTGTTGATTACCATAATTTACCCCATCGTTTTCATCTATATCTAAGCTAATTTTTTTTGATGCATTTCTGAATAACTTTCAATAAATGGTAGTCCTGTATATGTAGTGATAAAATTACAGTGAAGCGATCGCTTCATTATAATGATTAATGAAATACCAAATAGCTCCTAGATGGGACCGAAGCTTTTTAGAAAAGGATAAAGTCTTTCTGACCAACCGAGAAATTCTTTGACGCAAAGTATTATTCAATCTTTCTATATAAGCTGTTAAACCTGAATATTCCCCACTGATTTATGTCTCTCTTCAGGAAAGACAAGCTCGTAAGCTGACCAAAAATCTGTATAACAAACTGCACACGGCCTTAAGACACCGTGGGTTAGAATTCCATAATCTATGCTGCCCCTTTTTCTCCTCTTTCCCCTAAGTAAAAACCCACAATTTCTTTAGTTTCTATATCAATCGCTAACCACAGCCATTGTTTATTATTTTTATTGCCTACAAATGACCACATTTCATCACATTGAATGGTGAGTTTACCTGTTTTTTTTTAGTACATTTAATAGAGCGTGAAACCTCAGCATACTTATTATTGACGTAATTCTGGAGCCATTTTTCTGACACGCCTGTTACACGGGTTATACCAGCTAAACTAATTTTTTCTCTATTTTAATTTATCAATAAGTTCTTTGGTTTCATTACTAATATAATCTCTTTGACTATTTTCGACAAATTGTCTCTGACAATTTTGACATTGATATTTTTGTTTTTTGTTGTGAATAGTCCCATTTTTGACAATATGATTACTGCCACAACTAGGACAGATTAATTTATGAATGGACATCTGAATTATATAGATTTTTTCTTATTACTGTCATAGATAATAGCATACTTTTTTCATGATAGTTGAGTTTAATTCTTGATAGTTTAATGACTGATTATTATGTAGCGATCGCCTAGATAAAAATTTTGAATTATTAAGCATAAAAAACTTAATGTTTTCAAGATTGATGTCAATAACTAATCATTTATATTGGCTTATCACTACATATACAGGACCACCCAATAAATTTATCAACAAAAAAACATTAACTTTTTAATTTATTGAGATAAAAGTTGATTTTCCCATCTACTCATTGTCTCTTGAGCAGCCAAAAATTATCCTTCAATAGTGAGTGTTTTTCAAGAAATAAGCGGCACAATAGAATCGTTGCATAAATAATTCCTATGATTTGATAAATTCTTTGAATCACTAATTATCCCAAAGAATGTTTAACTTGATTAACTTCTATTTTTTGATCTAAACAATCAGCAAATTTTTGACAAAATTTCAGATTTTTTCCCTTTATTTAACCACTAATAAACCAGCATCTTAACTGAAATAAAGGGAGTAAAACTTAAAATCCAATTTTTTAGTAACGGGAAAATTAAAAGGTAATTTCTGACTAAATAAATTCATTTATGTACAATTCAAAATATCATTAAATAATCAATATTTAACGATAATATTATAACTTATTAATAAATAAAAAAATCAGAAATTAATTGTTTTTACTAATATTTATTCCAGGGGAGACAAAAAATACAAACTGCTGGGACTGTGAATTATCTACAAGTAACACTGAATATATGTTTTGAGCTTATTTTCCATTTTCTCATGAATAATTCAAGTTAAAGCTGGTTAAGCTATCTGGCACTTCATCCATCATTACAATGCCTTATTGTCTAAAGCCTTATCCTTTCCCTTTTAAGACTACCTGTTTTGACGTCCATTTTTATTGAACTTGAAAAATCTTATAGTTTTACATTTTCTTTTGCCTATAGTTCACTTAAAAAGATTTGTCAGGGCGAACAGCCACAAAATTCAAGGCTCCTAAGATTTGATATCTTCCTTGGCCTATAATGCTATGATATTACCACTACGCTGAAACTTCGATGGGGGTTAACTTTTCTTACCCTAATGTAATTCAAGTCCTGATCGAGAAACTTGATACTAGTCAAACCCCTTGCGTGGTAACTCCGTTCTTTGTATCGGACTGCCCACCCGTGAATAACTAACAAATAATTAGGGTTTGCTGAATAAATCTAAAAAACTTACACAATAATGATTTTAGGTATTTTTCATCAGAAATAGTATCTAATTTTCAGCTAGAATAAACCTCTATAATACATACAGCATGTAAAGAAAAGTAGGCCAACGTGACACTCCACCAGAAAATTTTTAACTACCATTCAATGGCCAGTTATCCCCAGAAAATCCTTGGGTAGTGATGGCTATTTTAATTCCTTGGAAGAAATATGAAGATGTATATGCAATCTTTTTCTCCACCATAAATAGGAGCACTTAAATTAAATTTAAGAATAGAATTAAGGGCGTTAATTATTAAATAAAAATTAGGTATAAGGGGTAGAGAAAAAGTATAACAAATTAAGTGAAACCACTATTTATAAGAGTTTATTGGTCTAAAAACCTATAACAACCAAGATAATTTTTCTGCTTCAATATTGGTTCATTTTATAGAGAAAATAGGTGCATATTTAATCAATAAAATTAATTTAGATGTGGTGAAAATCAGAGTAAAACTCAGGAATATGAAACAAAAAAAAGAACCTTATTAGAAGATATTAACGGGACTTTAGTGAAAAAATAGTAAAAAAAAGGGTATAATGTATACCTGATATGTATTTTACGTTAATTACTGGCCTGGGAAAAGTTTGATGAAAGAAACAACTTCAGTGGCCATGCCCTCTTGTTTCCATCGATGGTGCGATCGCTTTAACAATGTCTTTAAAACAAAAGCCCAAAAAACAGGGTTTAGGGAATATATAGGAGGATTACTCTTGAGAAAGCGATCGAAAAAACTTGTCTCAAATTGCCAACAACACTGTAGGTCACACGTACCACAAATTACGGCATTTTCTAGTTCGAGCAAATTGGTCTGTAGATGCTGTGAATGAGCGTCGTCTTCAAGTAATGTGGGAACGTCGCCAAACAAAACCTTCTCGATCCTATTGCTTTAATTATAGACGATTCAGGCCACAGAAAAAGTGGTAATTTTACTGCAGGAGTAGGGCGGCAATATATAGGAGAAATAGGAAAAACAGATAATGGTGTAGTCGTGGTGACAACTCATCTTTATGATGGAGTTAAAAGTCTACCTTTAGACATAGCTTTGTATCAGAAAGCTGATTCTTTTCCAAAAGGAAAAAAAGACCCAGAATTTGTCAAGAAACCAGACGAGTGCAATGTCTCTAGTAGATCAATGTTTGTCCAGAGGACACCAACCAGAAATTGTGTTAATTGAAATTTGGCTATGGTAACAATACATCATTCTTAAATCAACTAGAGAAAAGAAGTTTAACTTATATAGGAGGATTAGCTAAAAATCGAAAAGTCATCATTAAAAAACAAGATGACATTAAAGAGGAAATTAGATTAGACAAGCTGGCAGAAAGTATACCTCAGAAAGCTTTCAACTTAGTTCAACTAAGTACAAAAAATGCTAGAGAAGTTTGGGTAGCTACATTAGAAGTAGAAATATCTAGGATGTCAGGTCAAAAAACTATAGCTATCGTTATGAATGCTAAAAGTTTTTCTGAGGCCACTGATATTAACTATTATATCACTAATAGAGAAGACAAATATGTAACTCCTGAGTGGATATATTCTACTTATTCTCAAAGAAATTGGGTGGAAGTTTTCTACAGGGAAGCCAAAGGATGGTTAGGATTAAGAGAATATCAAGTCAGAGATAAAATCAGCCTTAAAAGGCATTTTATTTTAGTATTTTGTGCTTATACATTTATTATCTGGCATCAGTTAACAGGAGGTATAAGAAGGCGTTGGGCTAACAAACCATTAAATACGTTTACTGATACTTTAGAAGCATTTCGTACCGCAATATCTTATCGTTTTGTTGAGTGGTTAGATGAAAACATCGACGTATTTACCGCTCATAAAGAGAGTTTAGGGTTTGTTTGGGCTTGAAATTTGCTAAAGTCCCGTTAAGGAGTTCAAAAATCAAGGTAAATTAATTTAAGGTAAATTAATTTAAGATGGCACCTGCGCTCCCAACTATCCGAAAGACTTAAACCTATTAAATCATGGCATAATTGAAACCTAAATCATCTAAGATATTCTCTTAAAATGCTGTGAAAATCAGTTTCACAAAAAAATCATTACTCACCGTCAAACAGCAAAAAAAAGAATATTTAAAGGTAGGTAAAAAAAGACGAATAACTACTAAAGCTATCAGGAAAGCCATCAAAAAATAACTGAAATATGTAAGTAAAAACTTAAGCACCCAAAAGGCTGTTAATTGAGAATGGTGTCCGTCATGAAAGTTTGAGTATTAGAAAATATAAAACATTGTTGGATTTCTGTGAAATTTAGCGTCAACAATAATTGATGTGGGATAGCAAAGAACAACGAATAGATGGTATAATAATATGTTGAAATCAACCTGATATGCGTCTAATAGTAAGAGTAAAAGGGGGAAAAGTACAGAATTTGGAGCCAAAATATCTGCAAGTTATATGGATAGATATATATTTTTACATAGAATAAGTTAGGAAAACTATAACGAATCTTGAGATTTAAAGGCTTAAGTTGAAAAGTGGAAAAACTATATAGGTTATTACCCAGAGTCAGTTCATGCAGACCAAATTTAGCTAACATGAGAAAACCGAAAATCATGTAAAAATAAAGGTATTAGAATCAGTGTTTCATTACGGAATATCACCCAAAAATTTTGATAAAGAACAGAAAAACAAGCTCAGGAGTGATGAAATATTAGGTCACCATATTGAAGGTAAATTTGCCCAGCAGCAAAAGAGGAGTCATAAGAAAGTAATAGCTAAACTTTCTAAAACTTCTACAACTGCAATCGCAATTACTTTTTTTACTTTCTTAGTAATCAACCTTTCTACTCTCTTAAAAGAGGCTTTTTCTCTTTTTTGATATTTTTTGTCTGGGTCTTTTTAATAATTTCAACTTATAGTTGAATAAATGATGATAATTTTTGATAATCATCAATTTTTTTTGAATAATAAATCAACTATTTTCATACTTTTTCAGAAAACCCTAATTTAGAACAACATATGTATTCAAAAAAAACAAATGAAAACTGAGTCTAGAGCCGCAAGGCTTTAGACTCTATTTCTTGGTAACTATTTACTTACAAGTCAATTATCATATAATTCTTAACTATCAGGTCTTAGTATAAAAATAGAAGTACTAAATATCCCTATATCAAGAATCTAATAATTTTAAACTCCCCGGGCAGGATTCGAACCTGCGACCAATCGGTTAACAGCCGACCGCTCTACCGCTGAGCTACCGAGGAACGAATGTTTAATCACTTATTCCTAAGTACCGATGATTTATTATAATCTTAATTCAAGAGATTTGACAACTCCTTTTCTATATTTTTTTATTATATTTAACATTAAAGAAATTTATAAATTGGAATTGAGTTCTATAAAACTATGTTGTACGATAACAATCATTTTTCCATTCTCAATTCAGCTAAACGCTTTTGAGATTCTGGATCTAAGTAACTAGCCAGAAAACGACCTGATGCCCTTTTATTTCGTTGACATCTACTCCGAACACAATTCGCTGCACTTTCAACATCATGGGCCAGCTGTTGGGAAGACATCCATTCGGCACCATAACCAATCACAGTAAGCCTTTGCACTCTATCTGAAGTAGCTACAATTAACCTACTTCTAGACAAATGGACTTCAGTACGAAGACTAGCACAAGCTTTCTCTATATATGTGTCTGCTGTTTGACCAAATTCTGTATAATGAACCGATAACTTATCAGTAATAATTTCTTTTGTAGTAGGAGTATATTGATATTGAGAATCAAATACTATCTGAGTATTTAAGTCCTGACTAGCACTGTAATTTACCAAAGCCTCAATCAAATCTCTTCTGGCTGTTTCTAAGCCATGAAAATTGCAAATTTCTCGGAGACGAGACCATAAACCAATGACATTATAGCCATCTACAAGCAGAATAGTTTGTCTTAAAGGGCGTGACATAACTCAAGATAATAATTGTTCCAAAAATATTAATAAATACTAACTATTATAACACCTATCCAAATTTTATAGTAATGTATTATTTATTACTTACCCAAAATTATCCACGCTACTATGTTCAATATTCTGAATTTTTAACGAAAAGGCTTAGTGATTTAAGTTAAGTTGAATAGTTACCGCTTAAAATGAATCTTTAATTAAACGTTGCTTTAAAAATTCAGGGTTGCCTTGTGCTACTACCTGACCTTTATCTAGTAAAAATCCTCCATCACAATAATCTAACTCATTTAAGCGATGAGTAACCCACAGAGCAGTAATACCTCGGTTTTTCACCAAACTTTGCACTTGAGTCAACAAATCTAATTGACTATCTGGATCTAGTAAAGCTGTCGGCTCATCTAAAAGTAAGATGTCACAGTTTCGAGCAATAGCACCAGCAATAGCAATTCTTTGTTTTTGTCCCCCACTCAAAGCATATATAGGTCGACGTTCTAGTTCTAATAAATTTACAGTACTTAAGGCATCTTTAACCCGATTACGAACTTGAAGTTTAGATAGTTTCTCTGCAACTAGACCAAAAGCTACATCTGCTCCTACTGTAGGCATGACAAGTTGATGATCAGGATTTTGGAAAACAAAACCTATCTTTCCTTCAAAATTAATTGTTCCTGACTGAGGAGACAAAAGTTTAGTCAATAATCTTAATAAAGTTGATTTACCACTACCATTAGTACCCAAGAGCATCCAAAACTGTCCCTTGGGTACTTTTAGAGAACAAGAGCGTAATACTTGAGAGCCATTAGGCCAATTAAAACAAATATTCTCTACTAAAATTGCTGAACGAGTGGCAATATTGGTTTTATCCTTTGGGTTCATTGAGCTACAGTTACAAAACCAGGTGGCCTTCCAGTCGCAGCAGCACCAGATTTTTGGGAAATTTGAACACCAGAAACTTCACTCATTACTACAGCAATCTTTTTCTCCGGTATTTTCTCACAAGTTAATTCTAAAATTTGAGGATTTCCAGAGCGAATAGACTCAACGATTTGTTCATAAGTAGATTCAGCATCCTCAGCGGACTTACGTTGAATTGAAAATGGTACAGGAGTGTACTTCACAATGATATCAATAGTGAACATTTTTTAATTAGTGAGTGTAAGATATTAGATTACTTATGTCGCCTTGGTTCTCGGCAGTAATAGAACATATATATGGGTAATAACCAGACTTTTTTGTTGCTTATCCAGAATTATACCACTCATAGTTGCAGTTGGCTGCGGAACCAGAACCTTTAACTACTTTGTTTCTTCTATTAGTTAGATTGTAACATTGGGTCGCAAACTATAAACCTTAAATTTTTGTATGCAAATTTCACCTAAAATTGCCAGAAGCCCAGTCCTATAGTATTTCCTAGTAGTACCTACCCCTATTTCTACGCTTACACCGAGTAGATCGGGGTTAGTGATTGTATATTATAACTGTGACATATAATCATAACTATAACATAGAACAAATATTAAGAGTTTATCCAATTCACATTATTGCATGCCTACTTATTTATTATAGTAAATGTAGTCAAAAGATTAGCTATACCTTACTAGTAATTGAGACAAAAATCAAAGGTAATTAACATCACTACAACGTTTTAGCCCAAATAATTTTCACAAGTAAATTCATCATAAATAGTTATTTTATCCTTTACATAAACAATAAAAACCTCAAGACAAATGACTTATAAAAGCTTTTTTAAAACAGCAAAATATAATAAATTTTATTAGACTAAAAAAACTAAAATTTCTAGCTATACTTTACTTTTATCCTAAAATATAAGGTAGGAAAATTACCTAAATAGAAAAATTCATCAAACCTAGATTTTATTAAATCAATATTGGTATGATCTCTAATGTAAGCAGATGTCAAAAATTATATTGCACCCAGTAAAATTTCTATCAAAAATTTTCTCCGTTTTAAATACTCATAAATCATGTTCTTTTAATTACAGAGTAAAGTTAGCTTTGACAATGCTTATTGGCATACTCCTAAAATCAAAAAATATTCCCTTTCTTAGTTATAGAATATTGACCTTAAAACCGATCTAATTTTTCAATATTATTTTAAAACTTATTTTGAAATGGTAATAGTGATTCAATCTTTTAAACATTACTTAAAGTAGTAATCTCTAAATCTAGACTAATTGATTTATTATTTTCTGGTAAAGCTTCTAGATTAATATCTAGAACAAAACTTACAAAGTAACGATCAGCAAATTATTTAATTATTCCAAGGGATATAGATTTATTTGGATTAAGCTTGTAATTATTACCTACAAAAGGAGCAGTTTTTTTGTTTTTATAGATTTAGATTGAGGAACTTTAACCTTTATTCTTTGACGTTTACCTTAACAACTATTAAATAAACTTTTTAATACTATTAATAGTATATATAGATTAGCTTAGTCCTGAAATAGATTTTTCTTCTGGAAATTGATCAGCAGATCTTCTTGCTCTGAATACTTAAAACTAGGAAATTGTATGAAAACTATGGGCTAAAAAGCCTATTAACATCCTCTGTTGCTGAGGTTGTGCAGAAGGTTCTTGCGAGCCGAAGCCCAAGAATCTTAATTTATCTTCACTAGCGCAAAACTTGACCCTACTCTTACCCCTGTCGGATGCGTTCATTTTTCTCTTGGAGTGCCTATTGACCACTAAATAATTAACATTATTAAATTAAATACCTATTTAAAAGAAACTAAAATATCCACTTATGGGCAAGGTTTTAGGCCAAATTTTTGGCTGAAGGAGAAGTTATGTTGCCAATTAAGATTGCTTAAGGGAAAAATCCAAAATCTAAAACACTAGATCGGAAAAAACTTATTTTTCTGGTTGCCCTGAGCAAAAATTACCTCTATAATGAGAATCACGGTAAAAAAATTAAACAATGTTTACAAAAGTTCTTATATTCTGCTCAAGTAGAACACAATTATTAATACATTAATGATGGTGGAGGACAAACATTAGCCGTAGTTATCATAATTATTTGATTTGGAGAACTATTTAATGACTGTAGCAGTCGGACGCCCACAATCTCAAAGAGGAGCATTTGATGTCCTCGATGACTGGCTAAAACGCGATCGCTTTGTATTCGTTGGTTGGTCTGGTATACTTCTCTTCCCATGTGCTTTCTTGTCCATTGGAGGATGGTTAACTGGGACTACCTTCGTCACTTCCTGGTATACCCACGGGTTAGCCAGTTCTTACCTAGAAGGATGTAATTTTCTAACAGTTGCAATTAGCAGCCCAGCTTATAGCATGGGACATTCCCTACTCTTCCTTTGGGGCCCAGAGGCTCAGTGGGACTTTGCCCGTTGGTGTCAAATCGGTGGTCTCTGGTCATTCACTGCCCTACACGGTGCATTTGCTCTAATTGGATTCTGCCTACGTCAGATTGAAATTGCTCGTTTGGTTGGAATACGTCCTTACAATGCTATTGCCTTCACAGGACCAATTGCAGTATTTGTAAGTGTATTTTTAATGTACCCATTGGGTCAATCAAGCTGGTTCTTTGCACCTAGTTTTGGTGTAGCTGGTATATTCAGATTTATCCTATTTTTACAAGGATTCCATAACTGGACACTCAACCCATTTCATATGATGGGTGTAGCAGGAATCTTGGGTGGTGCACTTTTGTGTGCTATTCATGGTGCTACAGTAGAAAACACACTTTTCCAAGATGGAGAGGCAGCAAATACCTTCCGCGCATTTGAGCCTACTCAATCTGAAGAAACATATTCAATGGTGACAGCTAATCGTTTCTGGTCCCAAATTTTCGGTATTGCATTTTCCAACAAACGTTGGTTACACTTCTTCATGTTATTTGTACCAGTAACAGGATTGTGGATGAGTTCCATAGGTATAGTGGGTTTAGCATTCAACCTACGAGCTTATGACTTTGTATCTCAAGAGTTACGGGCAGCAGATGACCCAGAATTTGAAACATTTTATACCAAAAATATCTTGCTAAATGAAGGTATCCGAGCTTGGATGTCTCCTGCAGACCAACCACATCAAAACTTTATGTTCCCAGAGGAAGTACTACCTCGTGGTAACGCTCTTTAATATACTCTAATTTTTTTGACAGGATAAGTTTAATACTTATCCTTAATAGTTCCTACACTAAATATGTAGGAGCTATTAAAAAAAAATCAATACAGCAGTTTTCGGTTGTCATGAGCTACACTTATAGAAAATAATTTGGGCAGTGCGTCAGTAAAGTATGGGATAAGTAATTAAGTCGTTCCCACTCCAAGGATCGAGACCTAACTTAGCTCTTTACGCAGCAGTATTTTCTTTGGGACTATGAACCTAAATCCAATTAAAGTAGGTGCTCACCAACCTTACTGTTATCTCAGTTTGTTGCAAAAGCTGGCCAAATTTATTCTGTCGGCGATGCTATCGACCGAGCTAATCTCTGATAATTCCATTTGTGCGTTCCAATTACAGGGCAATGGTTTTTACCAATAATGTGTTCTATTACAGGGCAATACTCGTTCATACTCTCCCCAATCATCAGTTAGCCATTTTTTACAGATAGTTTTCCCTTCTTTTCCCTTCTGTGTTGATGAGTAATTCCTCAACGAACTGGTCAGTATGTTTATTTACTCTAGCACTTAAAATTAATCCATTGGATAAAGGGTAGGGGCTTGCCAACCCAAGAATCTCTTTCTGTCAATTCTTAATACTGGCAATGTTTTTGTTTTTTTGGACGAATCACCAAAACTCATCACTGCTCATTTGTGAGGTATTGATATTCTGGATATGAGCATTATGAATCAATTTTCCTTTTTCAGAGAGAGCTCTCACTAAAGTAACTACCGTATCATAGGCCAAATTCACTGTTCGACTAATCCCTCTCAAACTACTGCCCTCAACGTGAGCCTCTAGAACCATGCGTATTTGTTCAGGTTGAATTGTTCTACGATAGTAGGTAGTGTCAAAAGTATCAGTGAAAGCTTGTAGGCATTCAGAACAATAATATAGTTGACAACATTACTGGTCTTTCCACGTTTATGAGTTTTCTGATGGCCATATAGAGGAAATTCTATGATAATAGAAAGTATTTAAGGACAACGATTATATTACTATTCCCACACTTTCTTGATGCATTACCATAATTTGATTATATATAGGTAGTCTATGTAGATAGATACGAAAAATCCTAACTATATTAAGTTTTTTCAAGTAACTCCAAGTTCCTTGAGATAGTTGATTGAAAAATAAATTTACATTTTGTTAAATATCCAGACATTTTAATGCCTACCTACTTACTTATAAAATCATATTTAATATATCGGTAGTGCATCAACAAACTGTGAGATAGGTAGTTAAATAATTCTACTTCCAAAGAGCAATATAGCTGCCACACTTGCTCACTTAGGCCTAGGCCAACTTAGATTTGTGTAACACTATTGTTATTGCGAGTATGAACCAATATCTAATTAAAGTAGGCCATCGCTAACTTCACTATTACTTCTACCGGCTCCCAGATATTTCTTCCAGAAAAAAATAGATAGAAATTTAACGAAAAATTTATTTGAAAACCTTACCTAACCATAAGGCGACTTTTCAGTTTTTTTTTGAATACATCTGTTGTCCTAAATGTTCATTAATAGTCTTGCTTGGGCCTACTAAGCTCAAAAACGGATTTATAGGAAAGGCTTTTGAGAAGGGTTAAGTTAACCCTAGCAACGATAAATTGGAGGAGCATGGAGAATGCGGATAACTTCGTAAGTGCAAAAAGTTAACTCACTGAGGAAACTTGCCTCCAGTATCAATGCCTCCCCATCTAAGAATGGGAGAGAATATTAAAACTATTAAAATATTGAACATTAAGGTTGAGTTATCTGGCAAATACGGAATTAAACTTACAAAAGATTCCAAGTATATGAAATTTAAGTATTAATGATTAAATCTTTGTAGCGCGGCTATCTTGTCAGGCAGAGCTATTCCCTAGTCTTTATTAAACCGAGCTGGTTGCCTTTTTTTTAGGATCCTCTCTACAAAACTGAGCTACACAATACTATGGCTTTGAAAAAAAATTTACAATACAATTGCATTCTGAAATTTTTGTGCTAACATAATATTATTAAGTGAAATAAAAAAACCACTTAGGGAATAAAGGAGGTGATGCCTATGTCAGATAGTAGTAAACGCATGGGTCACCTGATTGGAAAATGCCGGCTGTGTGCCAGGACTGCTCTCTAGTAGTTAGCTTATGTTCCTTTTTTATTATAGGAGCTATAATATCAACCGATAAATCACTACCAGGCTGACCTAGGGTTTCTCCCGGCAGTCAGGTTTCAATCAGTGTGACCCCCTAGACCGCTCTTATACAAATTTAGTGTTATAAATATATGATATTGAAACACTATCCCAGATAAGAGCGGATAGTTGCTTATTTTAGTAATTTTAGGAATAGTTCAATGACTGAATTGCTGGCTGTAGAAGAAATTAATCAACGTATCAGTCAAATATCGGACTGGAAATTAGAAGGAAACAAGCTTAAGTATATAAAAACAGTTAAAAATTTTGTTGAAGCTATTAATTTTGTGAATAAATTAGTAGCTCCTGCTGAGGCTTCACAACATCATCCAGACTTAGAAGTATCTTACAATAAAGTGACAATCATATTAACAACCCATAATTCTGGCGGCTTAACAGAAAAAGACTTTAAGATGGCTAAAACAATATCTGGCTTAAGTTAGCTAAATACTCGATTCATCTTACACCATAATTGTTGTTAGAGTTGTTGTGGCAAAAAATTAAAGAAACAGCTTAAAGATAGAACTGATTCTAGCTCAAACTGTGGTATAGTAATAGGCCCAGATATGAATGTTCAGTGCATTCTGTACTTAAATAATTTGTCTATTCGACGTGATATGGGGAAAAGGAAAAGAGAATAATGCTAACTTTACAGTTGGGCATATTAATATTTGACTTTACTGAAAAAGTATCTTTTCTCATCCCTTGCTAAATAATTAATCAAATGAAAATCTATGCTGTATTTTATGTTTTTCATTATTAGAGCTTGCTGAAAAAGTTTTACGAGTTAGGTGTAAGGAATTAATAACTGGGAATAGGCTATATAGCTATATAGCTGTTTATTTTTAGCATTTTTTTCAGTCAGGTAAAGGAAAAATAACTAATTTTATTCATTTAATCGTTTTCTTATAATTTTTCAACGTCTGATATCAAAGCGATTTAGCATCTTTAATTCAAGCTAAATTAGCTTCTGAAGTATTTAGTGTAGTATATAGATAATATAGAGAATTTAAGGCCATTGTATTGGCTAAGTAGGAACTATATTATGTCAAGAATGATTAAAGAAAGAAACTATAAGCCTGATAATTAGGTAATAATATCTTAAATGGGTTATAAAATGGTTATTTATTTATTTAGCAGCCCCTCAGGAAAAGTTAATTAGTGAAATTCTAAAAATTTAATATGCCTAATTTCCAATCATCTTTTCTAAGTACACTTTTATTAGAAAAAATATTATATTAATTAATAATTAAGTTTATTTAAGCTTAAGGCTATTGACTAAGCCTAAACTATGATCCAGTTAAATACACTTAAGTTGTTTCAGGAACTTACTGAGACCTCTGAATTATTGATAATAGAGCAGCTACTAGATATTGGAGTAGCTCTATCTGACACTTACAATTTGGGTGAACTATTAAATTTAATACTGTCCAAGAGTCGGGAAATAACTTGTAGCGATGCAGGTAGCGTTTACTTAGTAGATGAGGTAAATTTCAAAGAACGCAAGTTAGTTTTCAAAGTTGCCCAAAATGATTCTATTCCAGAACTAGCTTTTCAGGAAATCGCATTACCAATTGACTTTAAAAGCTTGACTGGGTATGTTGCTTTAACTGGTCATACTTTAAACATACCAGATGCTTACAATCTTCCTAAAGATATTCCCTATAAGTTTGATGAAAGTTTTGATGAGAAAACAGGTTATCGCACTTGTTCAGTCTTAATTTTGCCAGTACAAAAACAAAATCAGGAAATTATTGGAGTACTTCAGTTGATTAACCGTAAGGTTCAACCTGATGTTGTAATTACAAAAGAAAATGCCAAAGAATTAACTAAAGCATATTCAAAATGGGAACAGAGAATATTAATTTCTCTGGCTTCTCAAGCTGCTATATCTATAGAGAGAAATAATCTACAAGAAAATATAGAAAATTTATTTGAGGGTTTTGTCAAAGCATCAGTACAGGCAATAGAGGCTAGAGACTCCTGCACATCAGGTCATTCAGAGCGAGTAGCTAAGTTAACGGTAGGACTGTGTCAAGAAGTGAATATAATTACTAATGGAGTATTCTCGGGGACATATTTTAGCAATGAGCAAATTCAAGAAATGCGTTATGCAGCTCTATTACATGATTTTGGTAAAATAGGAGTGCCAGAAGGTATTTTAACAAAACGCAAAAAACTATATCAAGAACAATTAGAGCTAATCAAGCAAAGATTTTCTGTAGCCCAGCGTACTTTGGAAATGGAATCTGCTCAAACCAAGTACGAATACTTGCTTAGACATTTATCTGGGACATATCAATCACATACTCAAGAAAGTTGTCCTTTGTGTCAAAAAATTGAAAATTTAGATTTAGAACTAAAAACAGCAATTACTCAGCTTAACAACTATTGGCAAACAATACTAATAGCTAATGAACCAAAAGTTTTAGCAGAAGAACCACTCAAGCAACTACAACAGATATCACTTTATACCTACAAAGATACAGATGGTCAAATTAAACCTCTAATTACATCAGAGGAAATGGCTCAACTTACAGTTCCCAGGGGAAACTTGACTCCTGAAGAACGACGAGCTGTTGAAGCTCATGTAACACATTCTTATGAATTTTTAAAGCAAATTGCCTGGACAAAAAATCTACAGAACATACCAGAAATTGCTTATGGACATCATGAAAAGTTGGACGGTAGTGGTTATCCTAGGGGACTAAAGAAAAACGAAATTTCTCTTCAAACCCAGATAATAGTTATCGCAGATATATATGATGCTTTAACTGCTGGCGATCGCCCGTATAAACAAGGGTTACCCGTAGAAGCGGCTCTGAGAATTATGCGTTCTGAAGCAGCCGAGAATAAAATTAATAGCCATTTCTTGGAACTATTTGAACAAAAGCAAGTCTTTTCCATACTAGGACATAGTAAATAATACGAATTACTAGAAACTTTGCTACATTAAGATTTAAATTTTTATTTAAGTATCACCTTTTAAAGTAAAAAGGCTATTTGATATAAGTGGAAAAAACAAAGATGTAGATGGAGAAATAGGGATAACTGGAAAACTTGAGAACCCCAAGTCAGGAAATATGCCAAATTTATCAATTATTCTAGAAGATAAATTAAGGAATTCTTGTCATTTAAGCTAATGAGACTAACCAAATATTTAGTCAAAGTTTAACGATACTCGGAGACTAAATTCAGCAGTAAATCTTATTAATACCCTCCCCAGCTGTTAGGGGTGAGATTATTTCTATCGTTGTCTTACCCAAGGGCAGGTTGAGGTTTTACACTTAGCAGGTCCTTTGCACTCCTGAATTCTGCTGCAATTTATTGTCGTGAGGGTGAAACTTGACCCTAGTCAAACCACTTTCCTAGTGTGTCAGTTTTGTTGTCTCAGACTCCCTGCCCGGAAGTAATTAAATAACATTTGGGAGCAAATTTACATAAAGAAACTAAAAATTTAATTGCTTATACACGAGGCTTTCAAGCAAATTTTTCTTTAATTTCCCTATTCTCGTAACCCTTTATCTATGTTTGTCTCACCCATCGTTAACTTACGATACTTTGAAAAAACCTTGCCTTTTAAGGTAAGAATATTTGCTGGAGTTAATAGTCTCTGGGATAGTAGTCCTAAGAATTTTTAACAAAGGTTGTTGATACAAAAAAATTGTGATAGTCTGTCAATCATCTACCTAACCTATATATGTACAAGCTATTACTTTTGTAGTTCTCAGCTTGAATATACCTAAAATATTAAGGTGAAAAATCTAAACTTTGTAGTAAAGGTCATAAAAGAGTCTGTTTGTGCTATAAGAAAGTCGAACAAATATCAAAATTTGTTCTAGGGCTAGAATTATTTTAATATTGCTGGAAAAAACCATGTTCTGGAAAGATAGATCCAGATTCAATGAAAAAATTGGACTACCTGCAATTCTAGTCCTTATTAATACATAGTTAATACCCAAGGAGATGCGGGTTTATAAAGCAATAATTAACAATCCTACCCTATTAAAACTAACTAAACAAAAGAGCCAAATAGTCTCTCTATAATTGGTGTGAGGATGAGAGAAAAATGTCAAAAACATTCTGGTATTGTCTAATACTTAGTCCAGCAGTTTTAGGAGCAACTCTTGTTGCATCCTCATACGCTCTGGCGACTGAAAACAAGCAAACTAATACAGTTATTCAGCCTCAAGCTGCAACAACTGAAAATATATCAATAAATAATAATATAGATATACAGGAACCTGATCTATTAGCTCAAGTTACTGCAACCAATTCGACTAATTCTGTTGGGAATACACCTGCAACTACCATACGACAAATTAACCGCTATGGTAGAGAAGGTCGTAATCTTCGTCGACCAGGTCTTCGTAATATTACGAACAATAGGAAACCAATAAAAGGACAAGTTACTTCTGTATCTCAACTTTCTGATGTTCAGCCTACAGATTGGGCTTTTCAAGCATTACAGTCTTTGGTTGAGCGTTATGGATGTATCGTTGGATATCCAGATGGTACTTACAGAGGCAACCGTGCCTTAACTCGTTTTGAATTTGCTGCTGGTGTTAATGCTTGCCTAGATAGAGTTATGGAACTTTTACAAGCAGCTATAGAAGATACCGTAAGTAGAGAAGACCTGGCTATTCTGCAAAGGTTACAGGAGGAATTTTCTGCAGAATTAGCGATTCTCCGGGGTCGTGTTGATGCTCTAGAAGCTCGTGCTGCTGAATTAGAGGCTAATCAATTTTCTACAACTACTAAACTTAGGGGTGAGGTAATTTTTGCCCTTGTTGATAACTTTGAAGACCAAGGAAAATATGGAGCATTTGGTGATACTATCCAGGATGAGGATCAAACGGTATTCCAGTATAGGGTACGTCTGAATTTCAATACTAGCTTTTCTGGTGAAGACTTATTATTTACCAGGTTACAAGCGGGTAATGCTCAAGCATTTAATCAAAAAATAGCTGAGTCTGAGGGACAGCAAACCTTTAATATTCTTGACCGTACAGATGATACGCTTCAACTAGATAAGCTTTTCTACAAGTTCCCTGTCAGAGATAATATTAGAGTAACTATTGCTGCTAATAAGGTAAGTTGGTACGACTTTGTTCCTACACTTAATCCTTATATGGAAGATTTTGATGGAGGCAGCGGTTCTCTAAGTGCTTTTGGTCAAAGAAACCCAATCTATAGGTTAGGGGGTGGTAAAGGACTTGGAGTTGAGTATGATTTTGGTTGTAAAGACCAATATGCTTGTACCTATAGTCCATTTTCTGTATCTTTTGGATACTTAGCGGCAGAAGGTGAAAATCCTAGTCAAGGAAAAGGTCTGTTTAATGGAGACTATGCTGCACTAGCGCAACTAACCTTTACTCCCATCAGAAATTTCCAAGTTGGACTTACCTACAATAAAGGTTATTTTGGTCCAGGGAACTTTGGATTTGATGATGGTGCAGCCACAGGTCTAGGTGATAATGGTAGTTTAAACAGTGGATTTGTAGGAACTGGTATTGCTAACAGTGTTTATGGTTTAAATGCTGGACTTAATGATCGTCGACCAGGTTCTGTCAATATTAATAAGTCAGTTTCGACTAATGCTTATGGTGTAGAAATGTCTTGGCGAGCAGCTGATTGGGTAACTATTAATGGTTTTGGTACATATCTTGATGGGAAACTAATTGGCAAAGGTGATTTTGAAATTTGGACTTATGGAGCTACTATTGCTTTCCCTGATTTATTGAAGGAAGGTAGTCTGGCTGGTATTGTTGTAGGTCGGGAACCTTATTTGAATGACTTAGAACTTCCTAGTGGTTTAGATTCAGGATTACGACAAGATATGTCATGGCATCTTGAAGCATTCTACAAATATCAACTTACAGACTACATTTCAATTACTCCTGGTGTGACTGTAATTACAAATGCTAACCAAGATGATGATAACGATGAGTTAATTATTGGTACTATCAGAACTACTTTTCAGTTCTAGTGGTTAGTTGGAAAGGTTAGGGTGGATAATACCACCCTATAAATTAATTAAATAGGACTTATTTGATATCCTCTCTGGCTGTTAGCTACTGGAAAATAAACGTATCAAATATACTTAGTGAGTTGACGTTTTTTCAGAGCAAAGCTCCACGATTCAAAATGAATACATCCACCTCTCTTTCTATCCTTCTACTTAGGAGATGGGGGTAGGTTATATTTATCTTGTGCGTGCGTTTTTTTGTGTCAGATTCCCCGGCGGGTACTAATTAATTAATAATAAAATAATAACACATGTATTCAAAAAAAACAACTAAAAAGTAGCCCCTTTATGGGCTAGGCTTTAAACTGAATTTTTAGGTAAAGGGAAACTATAAAATCACATTTGCCCTGCTATATTGTTTAATGGTTTTATGTTTTGGATAATTACTTATTAAACTTAATATGTGTTATTTAAGTCTTTTTTATTGTTCTGCTAATTCCTTTATTTTTTGATAATTCTTTGGGAGCTTAACAGGGTATTAGAGTTGACTTGAAGGGAAAAGGGTTAATCTTTAGAGTAAATACATGTCAATCTTAACTCCCTAGTTCCACTCAGAATTGTAGGGTTTAAATCACCTCAAAGAATAATGACTGAAACCCTGAATAGATAATCCTTTCAAAAAGCATATAGAGAAAGTTGAAAATTTACAATTGAGCAGGGATACAAAATTAATTACACATTTTTTCAAGCTGAATCCCTTATAACGTATATATTATATAAAATTAGTGATGCCTGCAATGAGTGTTTAATGGCTGATAAAGTACAAGGTTTTAGGAATTTAGGCAATGGGAGATAGGTAAAAGAAATTAACATTAAACTTACCTAATTACCATAAAAATTGCTGAAATTAAAAGTAAAAAATCTCTAATCATGGAGGTTTAATATTATAAATAGTATATAATATATTAGTTGAAATTAAAAAATCATAAAATACCTAATATCTATATATTTATTTGATTTTATTTTTATTAAAAATTAACTAAATAGTAAGGTGAAAATATATACTATAGCTAGCAATCCGATTTTATTCAAATCAAAAATATTGCTACTTTTTGAAAATAGGTTTGGAAACAATGGTTAATGGATAAGACTTTGGGAGTTAATTTATAGTTTTTGAATCCTGATTATTTTAGATTCCTATATAAAGAAGATAAAGAAAAAACAAAAATGTATTTATTGATCAAAATTCATACATAATTTGTCTATAAACTAAAGCAATCATAACTAAATATTAAGTGTAATATCAAAGAATTTAGACATAAGTATGTTAATACTGATTTGTACTATTGAGGGTATAAAGCTTAATGGTTGAAGTCTGAATTTTTACGTTCTAATAACTGTTTTCTATCATTTATTTGTAGAGTTATAAGTCTAAGGTTAGAGATAAATATATCATGCGTATTGCTCATAATATTACAGAATTAGTAGGTCGCACTCCCCTGGTACAATTAAATTCTATTCCTAAAGCAGAAGGTTGTTTAGCCAAAATAATAGTAAAGCTAGAAGGAATGAATCCCGCTGCCTCAGTTAAGGATCGTATTGGTGTAAATATGATTAATGTAGCGGAGCGCGAAGGTTTGATTAAACCAGGTAAAACAACATTAGTTGAACCAACGTCTGGAAATACAGGTATTGCTTTGGCAATGGTTGCTGCTGCTAGAGGTTACAAGTTAATTTTGACTATGCCAGAAACAATGAGCATGGAGCGTCGTGTTATGTTACGAGCTTATGGGGCAGAGTTAGTATTAACTCCAGGTAGTGAAGGTATGAAAGGTGCAATTACCAAAGCACAAGAAATTGTGGATTTAAGCAGTAATGGATATTATATGTTACAGCAATTTCAGAATCCAGCTAATCCAGAAATTCATAGCAAAACTACAGCTCTAGAAATATGGGAAGATACGGATGGAAAGGTAGATATTCTGGTGGCTGGTGTTGGTACTGGTGGGACAGTTACAGGGGTGGCAGAGACTATTAAGGCAAGAAAGCCTGAATTTCAAGCGATCGCTGTTGAACCTTCTAATAGCCCAGTTTTGTCTGGGGGAAAACCAGGACCACATAAAATTCAGGGAATAGGAGCTGGTTTTGTGCCAGATGTTTTGGATACGAAGATTATTGATGAGGTGATCCAGGTTCCTGATAGTGAGGCGATGGTTTATGGTCGTCGTATAGCAAAGGAAGAAGGTATTTTATCTGGTATTTCTACGGGAGCTGCTCTTTGTGCGGCGATCGAAGTAGGTAAGCGTCCAGAAAATGATGGTAAGTTAATAGTCATGATTCAGCCTAGTTTTGGGGAGCGTTATTTAAGTACTCCATTGTTTCAAGAACTAGGGCCTACTCTCGCTGAAGTCAGGTAGATAATTACGGTTTGCTGAAAAATTATTTTTAAGAAGTAGGAAGTTAGGGGAGTGGTTAGGGACTTTGTATACAATGTATGTATAGGAGGAAGGTCGAATTATATATGAGATAGCCACCTATGGATGTCTTTTGATTTTTCTCCAATTATTCTGACCACAATTCTAAATTTTTGAGGGTTTAGGAGGTGATACCTGACCCTTGTTTTTTTATCCTCAAGGGTAAGAGGGGTAAAAGGGATAAAGAGTATAGTAGTTAAGCAAAATTGCTTAAATCTATCAAAAAAATGCGTTTTTCAACAATACACTTTATTTTTCTCAACAAACAAATAAAATATTGTCACATGCCTTTTATACTTTGCAACCTTCTTTTTTATTTTTAAAATCTAACAATCTATAGTTAAATTATTGGGTTTGAGATATCGGTGACTTCTCATGGTGAAATTACTATTTCATTACCTATTTATATAGAAGCAGATGATACTTTCTGTCGCCTTAGTTTATTTATGTGACTAGATATTAGGAAAGTTTAAGCTACAGTACTTCGCTGACTTTCAGATCTATTAAAAAGTTGGTGTCGTGAGATTTTATGTTTGCTTGAAAGCTTACATATTTTGTCTATGATTTCTAACAGTTAGATAGAGAATTATCACCTAATTATATATAGTATAGCAGATATTGATAGATAAATTACTCTGAGAAAGAGGATATGTTTTGTTAAGAATAAGAAGGATGTTTATTGGTATACTCCCGAAGTTATGCTTACAAAGTAAGTATAAAATTATTTACTCAGGGAATATCTAATAGAAGTTTTGATGTGAAGTGAGACCTTCTTTTTTTATTTATTTTAATATAAATATTATTATAATTATAATGACTGTATATATAATTGTCAACAGCTATATATAGAAAATTAGGACGAACCAGATAGATAACCCCGGACTTTCATCCTGAGGCTATCGTTCGGAATAGCGCGGGATTTCCCGCCGGGGTAGTTAAAGCATACGACTAAAAGTTAGGGTCGGCCTGAGATGCTCTTAGTCTTGGTGTGTCATAAGAGACTGCTATTGATTTTCTATAGAACTTGGCTGTTGATTATTTTGATTATTTTCAGAAGTTTGTGGAACTGGGCTCTGATGATTGGAAGTGGGTTTTAATTGTTGATTAGAGGGAGACTGCTGTTCATTTTCTATAGAATTTGGCTGTTGATGATTTTGATTATTTTCAAAAGGTTGTTCTTCTTGGCCTTCAGGTTGTTTGTTAGGCTCGGTAAATACAAAAGCTTTAAGTGATTCACCAATAATACGGTTGTTTACGGAGTATCCTGGATAGGTAGTATAAACAATCTGGCCACTGGGTTCACAACTGGGGACAGGTTCATGGTTTTCAGGATTAAAGATCTCTCCTGGGTTAGCAATTAAGAAATGACCAGGAGGGTCGTCGTTAACAATCTCTTTTACTAATTTTAATCCTTTTTCTACCAAGTTCTTTAAATTTGTGGGAATAGGTTCCGGAAATTTAGCTGCTTCTGGAATTTGTAAATCAGTTAATATTGAATTTTTCAAGTCTTCGACAACTTGAGGAAATTTATATTCTCCTATTGAATTATTGTCAGTAAAATATTGACTTCCTTGGTCAAATATATGTTTAGAAAATACATGTTTAATTTTGGCAATCTCTCGTTTACGATGAGCTTTTAAATCTGAATTTATTTGAGATAAATGATTGAATATTTCTTGACTAACTTTTGTGATTTCTTGATTTTTAAGTTGGATAAATTTGTCAGTTCAAACATCTCTTTGGGGGCGTGATTCATCAGAAGTAATTGTGTTACTTGTGTCGCGATCACGATCGCTTAACTTACTTAAAAGAGAACTTTTCAATTTACGGAGTTTTTCATTTTCCCTCTTAAGCTCATTTATTAGTATTTCTTGGCTTTGAATTTTTTGGTTTAGCAAGTATACTGTTTCCTTCAGCTCTTGCTTGTGTTTTTGGTTGTATCTTTTTTTTGGCTCTACAATCATTAGGTAGATATTATAAAATTTTTCTAGAAGTTTTTTAGGATTTTTAAGTGCATTTTTAAGAGAGTTAATTTGCTGTTTTTCTTGTTCATGATTATGATTGGAATACTGAATATCAAAATTATTTAATAACCAATTCAAAAAATCATTATTATTTTTATATACTCTCAAGCAATTTTCCCAATTTTCGGGATTATCACTTTGCTGTTTTTGACTTATAATTGTATCCTTAAATTGATTAAATTCCCTAGAGGATGAAACACCATAGGTTAATCGACTCCGCCTGGCGCGAATGATGCCTGGAGCAACACCGAAAGATGCTGCCCCCTTTAAAATGGCAACACCCGGACGTGGAGGCATAACAATTTTCTTGGCCTTGCTTCCAAACTCTTTTTTAATTCGCTGCCGGAGCACAGGGGAAGTAGAAAATCCGCCAACAAGAAAGATGATGTCAACTTCTTCATCTCCCAACTCTTTAAATTGATTTTTAACTGTTGAAACTAAACCATCTAAAGTTGGACGGAAAATATTTTCCATTGTTGAGTAACTTAGATGAATATTTTTATCATCCCCGTTTTGTTCATCAGCTAGCTGTTCGAGGATTTTTGCTTTACGCTTGGAGATAAAATTGTAAAGTCTGGTTGGAATGTTAAAGTAAATAACATCACCACTAGTTTCTGGATCGAAGTTGCACTTTGTTCGTTCCCACTCCTCCATCATCTTCAAATAATCAACAGGCTCCTGATCATGGAAACCCTTCACCATTTCAGCAGAGAGTTTTTCGGTCAAATATTCTTGAAAGCTTTTATCTACATATATCGAGCCAAAAGGACCACCTGTCCCAGGAGCTACCTCATCAAGTCCACCATCTTTGACCAACTTATGAACAGTGATACGGAAAATATTTTCCATTGTTGAGTAGCTTAGATGAATATTTTCATCATCCCCGTTTTGTTCATCAGCTAGCTGTTCGAGGATTTTTGCTTTACGCTTGGAGATAAAATTGTAAAGTCTGGTTGGAATGTTAAAGTAAATAACATCACCACTAGTTTCTGGATCGAAGTTGCACTTTGTTCGTTCCCACTCCTCCATCATCTTCAAATAACCAACAGGATCCTGATCATGGAAACCCTTCACCATTTCAGCAGAGAGTTTTTCGGTCAAATATTCTTGAAAGCTTTTATCTACATATATCGAGCCAAAAGGACCACCTGTCCCAGGAGCTACCTCATCAAGTCCACCATCTTTGACCAACTTATGAACAGTGATATCGACTGTACCGCCACCGCAGTCAATTATCATAATCTTATTACCAGGTGTTAGTGCATTTTTATCTTCCTCTTGGCAAAAGATAGCAGCTGCTTCTGGCTCTAATACAAGGAAAAGACGTTCAGCTTCATCATCAGAGGAATTAATTAATCCAGCTTTTCGTGCCGCACGACGCATCAAATCTTTATCTTCATTTTTCCAAATTGCTGGTATACTTAAACACCACCTAATTTCTTGATCCTTTAATTCTCCAGAGGTACTGTTTTTAATTTCCTTGAGAGCTTCGTCTTTAATGAGACGAATATATTTAGCTATCAAGTCAATAACATAAATTTTTTCTCCGTTATTTTTATTAATGACATAAGGTCAACTTTCGTCTTTTTTACCAGAATGTAACTCCATTTTAAAGTTACGGGTAAAGTAATAATCTTTAGCAGTTCCCTGAGCACGAAATTGAGCCAGTTTTTTCATTGCTGTATAGCCCCAAGCTTCTACTTCTCCTGTAGAAGAAAGCAATAAATAGGTTGCGGTTTTAGGATAAGACATGGGGTTATCAGGCCACAGGTCTCGAAAGACAGAAACGTCCGACTCTTTAAACTTATAAGCAAACCCAGAACGAGATGTTCCGAAGTCAATTGCTACGACGACCTCAAATGATTTGTCCATCTAATTTACCTAATTTATCAAAATAAAGTTTGTCCATGTCCATCTACTCCAATACAGCCCTTAATCTTCAGCTTTCGCCAAGTATCTAGTAAAGTTTCTGCTATAATCACGTAATTTTCTCTTCCAAGTAATAATATAAACTGGTTTAGTCTGTCTAAATATTCGTCATCTCCTGAGACTAAAACATATTTCATCACCTCTAAATTACTAACCTGATCTAAAGATTTAATTCCACGCATTAATAACCAAGATTCTACAGATTTTTCTATCTGTTCTTTCGCCCAAAACTTGTTATCTAGATAAATCAAACTACTAGCAAAATCTATCAGCATTTCTGGAACCCAAGCCGATTCTTCTTCCCCTAATTGCTGATATAAAGATTGATAAAAATAAACAAGATACTCAATAATTTTTTCTCGTTCTTCTGAGGGAATTTCTTCTAAAAGATTAGGTAATAATTCAGGAAGCAAAGGGCGTTTGCGTTCTTGAGGTGGAACATCTAAGAGAAAATATGCATCGGCGGTTCTACCTATTAAGAGAGAAACTTGAATAGCAATGAAACGAGAAAAAGTTTCTTTGTCTGAATCAAGAACTGTATAGTTACGATTAGGTAAATTGTTAGGATCTTGACCTCTTTCTAACAGTCTCTTTTCTCGTTTTATCAACTGTAAATCTGCCAAAAACTTCTTAACTACTTCCTCACCCCAATCTGCATCAAACTCTTCTGTTGTTCCCGTTTCTATTTTTTCCTGATTTCGTTGTTTTTCCCATTTTAATAACCTTTCTTTAACAGCAAAATATAATAATTCTAGCCAAGACAAAGGATCTTCTTTAGGCAAAGAATCAATATAAGGTTCTGGAAAATTTTGACTCCAATAACTATATTCTAGATGATAGTAAGTTCTTTCAACTAATGTGTTGATAACTAACATTGGTTTACTTTTCAAACCACTAAAAATAGTTTTAAAAGCTCCCTCTCCAGACAAAGCTTTTGTCATCCATGCACCGGTTAAAAAATCGACTTTTCTACCAGTTTGTTTATACTTTTCGAGGAAAGCTCTTAACCGTCTATTTAATCCTTGTTCAATATCAGGAAAAGTATTAGGTTGGCTATTTGCACCAGCACCAGCACGGTCATATTTAAGAATAGGTGGAACAAATAAAATGAGTAAATTATCAGATTTTACAATTTCCTTAATTTGTTCATCATCCAGAGTAAGAGGCCAATTATTTAATCGGCGTTGTTGACGAATAACTGTGAGATTATTTTGCAAATCAATAGCTTTTAATTCTCTAGCTAATGTAGCATCTATTTCTTTTAACTGAAGTTGTAAATCTTTTTGTTTTTCCTGTAAAAATATTTGTAATTGAGCCCGAAAAAGTTCTAATTGATGAGCATTTTCACGATTTAATTTACCCTCCTGAATTTGATGCTCCCTATTCAATCTTGCTAACTCAGTTTGTAATTCCCGATTTAACTTTCCTTCTTCAGCCTGAAATAAACGATTAATAGTTCCTAACTCAGTTTGTAATTGACGATTTAATTCTCCTTGTTGAGCTTGAAACTGTCTATTAAGATTACCTTGCTCATACTGAAATTGAAAATTCCTCTCCTCCATAACAGTTTTTAACTGTATTTGAGCAATCTGTATTTGTTGTTGAATACTATCTCTTTTTTCATAATATTCAATTAAATTATCATTATTGATCCGCAGAGTTTCCGATGACATTCTTGCAGACCTAGTTCCCCAAAAAAAATCGCTGAATCCCTCTGCTAAATGTTGAAACCAATTTTTTTTATTAGGTAAAAATTTTTCCATTTATTAGACTCTAATTTAATCAATAAACTACAAAGTATTAGACTTCTATTATCCCTAAGTTTTCCAATACCATAATGGATAAAGTTAATTGCTTCTAAGGTATTTCATTTAATTTATCAGTTACTAGTATTTTGATGTAAAGCCAGAGGTTTAAAATATGTATTATACTAAATACACTTATGAAAAGCTTCTTGTTTTTTTAATCCTTTAAACCTTTCAGCATAAATATCAGTAGCATAAGTATCTTAGTTTTTAATAAAGCTCTTGTGTAAACCGGACTTAACATTAAGAATACTTCTTTTATCCCTTTGAAAGGGCAGGTTTAAGACCTGACTTTTTGGTAATTAATTAACATATTAACAAATATGACGAATACTTCTTTTATCCCTTTAAAAAGGTAGGCTTAAAACCTGATTTTTTGGTCATAAATTAACATTTTGACAAAATCGCCATTATATGTATGCTATGGGATCGTACTAATACTGATTCAGAAGGTATTTATAGTCGCTATATTTGTTATTGTAGTTATTGGATAAAAATGGCTCAATGGTAAGTTCTGACTATTATAAAATCTTAAATGTTCATCCCACTGCAACTCAGGGACAAATTAGACAAGCATATCGTCGTTTAGTTAAATTATTTCACCCAGATACTAATACAGAAGTAGCAAACCACGAACGTATTATTAGTATTAATGAAGCCTATGAAGTATTAAGCGATCCTCAACAAAGAAAATCTTATGATCAGCAGCTTAATCAAAATTATCAAAGATATAGAAACATTAGCCAAGATTACTATAAACACAATAAAAGAAGGCAGAATATTGATGAACATCTGCAAAGATGGATAAATCATGTTTACAGACCAGTTGATACAATTATAATTCAAATACTAAAACCTCTAAAAAATGAAATTGATGATTTAGCTGCAGATCCATTTGATGATCAATTACTTGAATCTTTTCAAGATTATTTAGAAACTTCTCGAGGTCTACTTAAAAAAGCTCATAACTTATTTAGTTCTCAGCCAAACCCATCTAATTTTGCTGGAGTAGCAGCTCATTTATATTATTGTTTGAATCAAGTTAGTGATGGAATAGAAGATTTAGAATTATTTACTCTAAACTACGATGATTATTATTTACATACAGGTCAGGAATTATTTAGAATTGCTGATAAATTGCGCCAGGAAGCACAAGCAGCAATAAAAGGTATCTTTTAAGTTAGAAGTTAAATTCACAACGCTAATTACATTTGATATTTTACTAACATTCTATTAGTTTAGTTGTCTGAGGTTTAAATCACTAAAACTTTCAAAATAAGTTACTCTTTTAAATAAATTACATAAATTATAATTGTTAAGAGATACTAGGGTTAGTTTTTTGATTTTTAGGTTTAAGACTATTCTTTTGTTGCAACTAAATAAATAATAAATGTGGCGATAGATTACTTTTTTTTTATACCTATTTTTTAACTCATAGGAGTCAGTAATAATCTCTTGATTCCTATTTTTATAAAACAGGAAATAATTAATCGAACTACATCTAATAGAATGAGTCTAAAAATAGCACTGCTATAAATATAATTATAGTCATAAAAAAGTTAATTTTTTCAAGAGTTTTTTTACCATTATTTATCTTCTAAGAAAAAATCATATTTGTTTTAAAAAAATACTTATAGATAAAATTTTTAAGATAATCATAATATCTATTAATTTACAAAAATAGTCATCATAAATAAGCTTTAATAAATTGTATACTTATGAAGTTTCGGAAAATTAAAGATTTGATTATTTTTAATTCATTTATACTTTTAAGTAGGGTATAATAACTGTAATTAAAGTCAAAAACTACATTATATTGTTTCTGTAAATAGTTTTGCAAGTCTGACAATTTTAGAGAATCTTTTTCTATTAAGCAGTCAATTGTTTTGTCTTTTTCTGCCTGCCCTAAGTAACCTGACCTTCCTCTACATTAAAGTCTTAAACTTTCTACATCCTGAAAAAGCACTCGGATTTTCTATTGACTGATAAAATTGTGAGAAACTTTCAATAATTCTTTGACTTTATCTCATATTCTGCGCTTCAATTTGTAAAATTAGAATTAGTATAAAATCCGTAGCTTGCTTAAATATTTATACCATAAAAATTATCTTTATTTACCTTAATCAGGAGTTAAATTATCAGGTAAATATTAATGATAAATACTTACTGAATCTTTAACTCCTATTTACCACTATAATTTACTTATTACTTATTACTTCTTATTTTTTACTTCTTACTTTTGACTTATATTTCTATATTACGTTTTGTCCTGCGGAATATATGCTTTATAATAAGATTTTTCCAACAAAAGCATTTTTACTGCCCAAGCCATTTTCATTTATTTTGACTCTTTTTGTATTATTGAGAAAATAATCTAATTCATCTATAACATCATAATTTTTGAATCTTATAAAAAAGTTATTGAGTATGAAAAATGGAGCAAAAGAAAGAAAGGCTAATTAATAATTTATAATTCTAATAAATTTTCCTAAAGTAGTTATATATATTTTCAACAATTACCAATAAAAGATGATGCGGTGTTAGATACATCTTCATTTATGCCAGTCTGATAAAAATATATAATGGATAAAAATATAGTTAGTATGAAGGATTTATTTCAACAATTAAATTATCAAGTAATAGACTGAAAATATTAAATTCAAGGAAGGCAAGTAAAAAAAAGAGCCTCGCTAATCTTTCAATAAATAATTATCAAGCTAAAAAAATTAATTAATCAAAAAAGGAACACAAAATTATCAGATAATTTCCAATTGATTAAACAAGAATTACGTTATAAATTTTAAGTAATTAGGTAGTAGAAAAAAAATAATTTTTCTACTATAGCAAAATCATACTTATAACAATTTATCATCCTATTTCATTCTTTATAGATGATTGAGTAATTCTCAAATAGTAAAAAAATCATAAACATTATTTGACTCCAGTTTCTCCTATTGCTTACTACCAATAAATTTATCATTTTATGACAAGGTAATCAAAATAATTTAAATCACTAAAGTCAGCTTGGTAAAATTATTTTATCGGGACTTTAGTGAAAAAATAGTAAAAAAAAGGGTATAATGTATACCTGATATGTATTTTACGTTAATTACTGGCCTGGGAAAAGTTTGATGAAAGAAACAACTTCAGTGGCCATGCCCTCTTGTTTCCATCGATGGTGCGATCGCTTTAACAATGTCTTTAAAACAAAAGCCCAAAAAACAGGGTTTAGGGAATATATAGGAGGATTACTCTTGAGAAAGCGATCGAAAAAACTTGTCTCAAATTGCCAACAACACTGTAGGTCACACGTACCACAAATTACGGCATTTTCTAGTTCGAGCAAATTGGTCTGTAGATGCTGTGAATGAGCGTCGTCTTCAAGTAATGTGGGAACGTCGCCAAACAAAACCTTCTCGATCCTATTGCTTTAATTATAGACGATTCAGGCCACAGAAAAAGTGGTAATTTTACTGCAGGAGTAGGGCGGCAATATATAGGAGAAATAGGAAAAACAGATAATGGTGTAGTCGTGGTGACAACTCATCTTTATGATGGAGTTAAAAGTCTACCTTTAGACATAGCTTTGTATCAGAAAGCTGATTCTTTTCCAAAAGGAAAAAAAGACCCAGAATTTGTCAAGAAACCAGACGAGTGCAATGTCTCTAGTAGATCAATGTTTGTCCAGAGGACACCAACCAGAAATTGTGTTAATTGAAATTTGGCTATGGTAACAATACATCATTCTTAAATCAACTAGAGAAAAGAAGTTTAACTTATATAGGAGGATTAGCTAAAAATCGAAAAGTCATCATTAAAAAACAAGATGACATTAAAGAGGAAATTAGATTAGACAAGCTGGCAGAAAGTATACCTCAGAAAGCTTTCAACTTAGTTCAACTAAGTACAAAAAATGCTAGAGAAGTTTGGGTAGCTACATTAGAAGTAGAAATATCTAGGATGTCAGGTCAAAAAACTATAGCTATCGTTATGAATGCTAAAAGTTTTTCTGAGGCCACTGATATTAACTATTATATCACTAATAGAGAAGACAAATATGTAACTCCTGAGTGGATATATTCTACTTATTCTCAAAGAAATTGGGTGGAAGTTTTCTACAGGGAAGCCAAAGGATGGTTAGGATTAAGAGAATATCAAGTCAGAGATAAAATCAGCCTTAAAAGGCATTTTATTTTAGTATTTTGTGCTTATACATTTATTATCTGGCATCAGTTAACAGGAGGTATAAGAAGGCGTTGGGCTAACAAACCATTAAATACGTTTACTGATACTTTAGAAGCATTTCGTACCGCAATATCTTATCGTTTTGTTGAGTGGTTAGATGAAAACATCGACGTATTTACCGCTCATAAAGAGAGTTTAGGGTTTGTTTGGGCTTGAAATTTGCTAAAGTCCCGTTATTAAATATTTGATGAAATTGCTATTATGCTGACTCAAACTAATTATTAACCAGGGAAAATTTCCCTGGCTAAAAAACTAGGAAAATATTCTCTACTTTAAAATGGTTTTGGAAACAATTCTTGTTTTTTTACGTTCCATTTCTGAAAGTTTATCCCCATCTTGTAAGCGAGTAGCACTAGTTTGTAAAACAGTTGCAGCTCCTGTATCTCCCATTTGTAATGCTGTTTTAGCTGCTGTTTGTAACATTGTAGCTGCACCTGCTCTATCACCCTGTTGTAATTTTGTTTCAGCTATTTGAGTTTGCCTATATTTTGCTAAAGCTAAAATATGATTTTGTACTTGAGAGTTAACTTGAGGCTGGTATTTTTCCATAAAATTAGCTTCAACTAAAATTGATTCTGAAAGTAAACCTTCTTGATTTTGAGCAGGGTCATCATAACGAATTTGTAATTGAGCAATTGCTTGTTTTCCTTCTGGTAATTGCCCAATATAAGTATTGACTAAAACCACCCTTTCTATATCTTTCATTAAATCTCCCAGTCTAACTATAAACCCATTACCCTCTTTTTTTACTGGCAACTCAATAGTATCTGGTGCCACTTGTGCAATAGGTTTAAGTTCTGCTAACCTCACTTTAGGCATTAAATAAAATTGCAAATAAGAGTTAGTAATTCCTACAGATTTAATGCGATTAAATAATTTACTAAACTCCTCTATTGCCTGTTCTGGTTGTTGAATATAGGAAAGATTTCCCCCTCCAGCATCAGCAATTTTTTCCAAAACATCTTGATTCCAATCATCACCAAATCCTAGAGAATTTAGAGTAATATTATAGTCTGTTGCTAACTTTGCTAGCTTGAGACAAAGGTCATTATCCCCATGTTCATTTTCTCCATCAGTTAATATAAAAGCCTGGGAAATAGACTCTTTTCTACCCTTATTTAATTCTTCTATTCCTAACTTTAAACCTTTATCAATAGCAGTACCACCAGAGGCTCTTAATTTATTAATTTTACCCTTAATACTAGCAGAATCATTGATCATCTGATTAGGAACAATTACTTGAGCTTGATGGTCAAAAGCTACAACCGAAAGGCGATCGCCTTCCTTCAATTTTTCCACAAGTTGTACTGCTGCTTGTTTAACCGTTTCTAGTGGTCTTCCTTCCATAGAACCACTGTGGTCTAAAATTAAACATAAATTTAATGGTACAGTCCTTTCTAGCTGATTAGCCATCACCGAAATAGATAAGGCCACTTGCCGTTGAGATAAAGATTGAGAAGCATCAATATTAGTATCATTGAGAGCCGAACGTAGATTAACTTTCATAAATGTACGATTGATTTTTTTTCACTACTAAGGATATCTTCACAAATATAGGGAGAAGTTTCGATATAAATATCAAAAAAAATTAGCTGCTTAACAAGACAGATAATTATGGCAAAATTTACACAAGGAAAGGAAACACCATATCTGCACAATGTTGACTCAAAATAAAGTAATAGTAAATCTGTCATTTTTGTCCCTGAATTATGGTAAAATTCATCCCTAGACAAAAAACTTGTTTGAGCTTTATAGAATATTATTTTATGACTGGGATATATTAAATCTGTATCACCTATGCCTATGAAGTATACTGACCAATATTTTATATATCTAAAGACTAACTATCAATTAACACTATAGAAATAGCTCAAAATTTGTCGGTATTAATATAACATAATTCCAGGGAAAGTTTTTAATTTGTGGGAGTAAAACAGACTTCCTATAAGTATTTTTCCTCTGGTTTTCTATTTCCCTAAATTCAAAGATAGACCAAACAATGTTGGCTCAAAATAAAGTAATAATAAATCTGCCATTTTTGTCCCTGAATTATGGTAAAATTTATCCTTAGACAAAAAAAATTGTTTCAGCTTTATAGAATGTTATTTTATGACTGGGGTATATTAAATCTGTATCACCTATACCTATGAAGTATACTGACAAATATTTTATATATCTAGGGAGTAACTATCAATTGACACTACAGAAATAGCTCAAAATTTGTCGGTATTAGTACAACCTAATTCTAGGGTAAGGTTTTAAATGGTAGGAGTAAAACAGATTTTCTATAAGTATTTTTCTATGGTTTTTTATTTCCATAAATTAAAAGAAAGACCAAATTACTATAACTATAAAAAGCAATTATCATATCTAAAACAGGATTGAGTAGAGGTTACAAATTCAGGTGATTATTTTGATTTTCTCAGGTTTACTCAAAAGTATTGCATAAATTCTGTGCTAGAAAGTAAAAATCATATTTTCTAGATTTGTCAAAGGTTGATAGTAATGGCGAAGAAATCGGTAAACCTATGCTTAAAAGTTAATTTAGATATCGTTCATTAAGCTTTCCTAATCTTGATAATTATTAGTTAAATTTTTCATGATTTAATAGTAAATTGCTATATATTAAAGGAACAAAAATAGAGTTAAAAAGCATCATAAATCATATAAATAAATCTATCTCATAGACCTAAAATAAAACAAGTTTTACTCATAAAAAAAATATCAGATTCAGTAGATCAAGTCAAGTTGATAATATTAGTCGGTTCCTAATTTAAAAAATTATAATATTCAACCTACTTTATAAAACTCAATTCCTTAAAATTCTATACTATAAACAGATACTTATCTAGTAAAATTAGAAGGAAACAAGTTATATTCTATTAAATTTTTAGTAATCATTCAGTACTTTAGTAGTCAACTTGAAGGACTTTCCTATGTCATGCTTCGATATATATTAAAGTAATAAATCACTAAGTCAAACTTATCATCTTTTCGGTGTCGGAATTTTAATTATTCTTGGAGACTAATTTCTCTTTCTAACTGATAGTTGAATGCTGAATGCTGAATGCTGAATGCTGAATGCTTACAATTTTCAAGAAAGAGTCTAAGCAAATAGTCATTATTCCCCAAACTGAGAATAGATGCTAATATTCTAGTAAATCAAGATTTTTAATAGGTAACAAGAAAGTATAATCTATAAAAAAATAGCTATGACTTATAAAAAATTTCATTGTAAAAAAAACTGAGAAGATGACTGAAGCAGGAAAAAAAAAATTAATTTAATTGTTAAATATAACACTTTTCACTAACAGAAATAGAGCAAAATAATAAGCAAAACAAGATACAGATAGGAAGTATTAACTATTAGGTTAATAGTCAAATTCTATATAAAAAAATATTGGTTAGATACTACTGCAGCGAGGTTAATTTTTTAACATAATAGGTCATGTAACCAAAAAAGCAATTAAAGTTACGTTCCATCTCAGCATTTTAATTCAGGATAGGTAAACTTGAGAGTTATAGAATTAAACAAATTATACATCTCAATTACTTTATCACTGAAGATACAGCCTATTACTAGTAAATTATGGTACAGTGATTTTAGTAGATTTGAGTAACAATGTGGGAAAACTGAATTCCAGACTTCAAAACTATCTAATAAGAAGCTTTTAACTGTACCTCATAAACTACCAAGTGGAATGTAAATTTGTGTTTACAGGTTACAGTATCAGAAAAAACTTTAATGAGGAATTACTGTGAAAAATTGATAAAGATATTAACGCTTCAATGAATTTGAAACTATTTGGGCTGGACTTATTCCAAACTATAAACAATCATAAAAAAACAAAGTGGTTATTGCTTCCTCAAAAAAATACTTCTGTTTATACTGGAAATTTTGACTATTTTTAAAAGTCATGAAAAGCATACACAGAAAGAATATTTATCCGTGTAGGTAAGTTATGTAGAATATAACAATTATATCATAACCCATAACCAATTGTATCCACTACAATAATATTGCCTAGGCTAATATAATTAAAAGATAGTACAATACATCAATAGGAATTATCTGATGAAATCACCGATCAAAGCAGTTCAAACAAGCTCTTACTATGGAGACGTCTCTTTTCGTACACCACCCCCTGATTTAGAATCTTTAATGTTAAAAGAGCGAATCGTTTATTTGGGGCTACCATTATTTTCATCAGATGAAGTCAAAAGAAATGTCGGCATTGATGTTACTCAATTAATTATTGCTCAACTACTTTATTTACAATTTGATAACCCCGAAAAACCAATTTATTTTTATATCAACTCTACTGGCACTTCTTGGTATACAGGAGATGCAATTGGTTTTGAAACAGAAGCATTTGCTATTTGTGACACCATGAGTTATGTAAAACCACCAATTCATACAATATGTATTGGTCAAGCTATGGGTACAGCAGCAATGATTTTGTCAGCAGGGACAAAAGGATATCGGGCAAGTTTACCTCATGCTACAATAGTTCTCAATCAAGCCAAAACAGGAGCAAGGGGTCAAGCAACGGATATTTCCATTAGAGCAAAAGAAGTTTTAGTTAATAAGACAACTTTTTTAGATATTCTCTCGAAAAATACAGGTCAATCAGTAGAAAAGATTGCTAAAGATACAGATAGAATGCTCTACATGACTCCAGAAATAGCTAAAGAATATGGTCTAATAGATCAAGTTTTAGCAAGTAGAAAAGAACTACCAAAACCTTTACCTGCTAATGTTTAAGTGATAAACAAAATTAACAAGTTTTGGCAAGTAGAAAAGAACTATCCAGTATCAAGACTCAAAAATTAGGTCTCAAGCCTTTCCTTCTAAAAGGATAAAAAAAACGCCATACATATTTCAAGCCTCCTACTTCAATTGGGAGGTACTTAGAACTGATAGCTTAAATAACCTGTTACTTTTTAAGTCCTCAATAAAATCAAATGGAAAAAGTATTATGCCTATAGGTATTCCCAGTGTTCCTTATCGTCTTCCTGGTAGTCAGTATGAAAGATGGATAGATATTTATACCCGTCTTGGTCAGGAAAGAATTATATTTCTTGGTCAAGAAGTTACAGATGGGCTAGCTAATAGAATTGTAGCCTATATGTTGTATTTGGATTCTGACGATCCAAATAAACCCATTTATCTTTATATAAACTCTCCTGGTGGTTCTGTCACAGCAGGATTGGCGATATACGATACTATGCAGTATATCAAAGCAGATGTTATTACTATCTGTTTGGGTTTAGCAGCTTCAATGGGTTCATTTTTATTAGCTGCTGGAACTAAAGGTAAAAGATTGGCCTTGCCTAACTCTAGAATTATGATTCACCAACCAATGGGAGGTACTCGCGGTCAAGCTACAGATATTGAGATTGAAGCTAACGAAATTCTGCGGGTTAGATCGGAATTAAATAATATGTTGGCAGAGCGTACAGGTCAATCTTTGGAAAAGATAGAAAAAGATACTGACCGTGATTATTATATGTCTGCTGAAGAAGCTAAAGAATATGGTTTAATTGACCAGGTAATTGAAGAACGTTAAAGTTAAATAAAAAAATAAAGGAGTAAAAAGAACAAACAAAGTTAGTTGAGTAGATAAATCAGAATGTAAGCATTCAGCTATCAGCTAGCTTTCTGAGTTGTAACTCGGTTTTCCTTTTTTATTTCATGTAGCGAAACAGCTATTTATGAGAGGAATAGGTAAAAGCAATTGAGAAATTAGATAATTAAATTTACTCCCAAAGTAAGTTTATTTAACCTTAGAAGGAATTATTCATTATTTGCTGATAGCTAACTGATAAAAGCTGAATGCTTACATTAAAAATAAGTAGGTAGGTACGAAAAAACAAAACTATGTAAAGATACAGTGCCTTAATGTTGCCGGTGAAGTACATTAACAGCATTTACTAACCAGTTTTTAAATGTTGATAATTCATTAACTTAAGTGTCATTATAGATTATTATATCAACCATTTCTGTGTTATTTTTGAGGTAAGTTTTGCTCAAAAATATTTCAATTGTAATCATCATCATTTTATAGAATTAAAGTCCGGCTAGTATGGAAATAAATTTATAACTTTTGAGCCGACAGATTTAATTCTATATTCAATTAATGCTAGTTGATGTGTATGTAAATCATCCATGAAAACTGCCGTCTCTGGGCATAAACTACGGCAGTAAAAATGTTCAATAAATACTTTGAATGTAATGCTTACTATGAAATTATTTATTATCATTAAACATACTACTTATTTAATACTTACTGCACCAATTACTGTAACTTTCTGACTTAAATAAAACAGCTTCATTTTATATACTATAGTCCCTTTATGATAAGCATACATGAGTTATGGTAAAATCTACCATGACAATTTTTTTTATCTATAAATACTAAATTTTATAGCTCTATCTTTTGTATAAATTCCTTTCTATTATTCTCTAAATTTTTGTACTCTCACAAAAAATTGGATTCTACAAGTTTAAAGCTCACCTCACCTAAGTTTGAGTACGATACTACCCTTGTTCCAAAAATTATAGTCTGTTAACACAGTATTTATTCCCAACCATGATTCATTATACCTTTCTTTGTCAAGACTAAAAAAATATAGCAAGTTTTGCTGAGAATAATTAATCATTTTTTGAGCAAAATAAAATTTGAATCAAACAAAAAAAATCACCAGAATTTAGTCATAAAAAAATATCTTATATGTAAGAATTGATCAATTTTTTGAACAGCAAAAACCTAAAAAATTAATTTAATTAATTTAGACTTAGAATAATTAATCATTTTTTGAGTACAATGAAATTTGAATCAAACAAAAAAAATACCAGAATTTAGCCATAAAAAAAAATATCTTATATGTAAGAATTGATCAATTTTTTGAACAGCAAAAACCTAAAAAATTAATTTAATTAATTTAGACTTAGTAAACAGCTAAAAAAAAATTGCTAATTTTGAAGGAAAAAAATTCTCAAATGCTGAAATTCTCTTAAAGAATGAATTTAAAAATACTAAAAATCACAGAAAAGTTTATCAAATTTTTGCAAAATTATCGTTATCTACTTTCTGTAAATTACTCAGTTTATTGATTATTTTTAATTAAAAAATTATAGTATTATTTTATGGAATTAATATATTAAAAAATACGAACATTTATGTTATTATTTATCCTAGCTATAGCCTAAAAAAAATAGATTTTGACGAGAAAAATAGTCGTTATTACTAGTTAAAATTAGCCTAATCTAAATCTAAATCCTGTAGGAAAGTGCATTGGATAAATTGGCTCCAATAGTGATTAAATTAATTAGATATAAATGGCTTGATACTAAAATATTAGTTCATAGTAATAGGGCTTATAAATATAAATAAATCATGGATTTGTGTGAAAATAAAGTCAGAGTTGATTATATAATAGCTATGGTAAATAATCCTCAATTAAAGTTATAAGCTGCCTATGTAATTTCCAAAATAATTAATGATTATGAACAAAGGTTTAAATCTATAATCAAATTAATAGATAGTCATTTTATAAATATAAAAAAACTACAAATATAAAAAAAATATTCTTTAACCAAACTTTATTGGCTTGGCTCTTTATATTAGAAATCCAATCAATTATTTAGTGACAAAATAATAGTTGTGATCAAGGTTATTTATGCTAAAAAAATGTTAAGATACGTCACTTTTTTATATTTTTACCTGCTGATAAAATTAATTACATCTTACTTGATGCAGGTAAATATTATTCAGGAGGAAAGATATAAAATTGGATTAAATAAAAACAATTTTTTGTAATATTAGTAGAATTTAAAAATATAGTTTTTTTCGAGTAACAAGTTAACTTTTAGTTGTCTCCATTAACTTATGTTTCTAGTAAATACAATTTTTTAGACAGCATTGTTGAAATAAAACATATTTTTATCAAGCTATAGTGGTAACAATTAGTTTAATTTTTTTTGAAGTTAGGAGCTAGAATTATTGTTAGCTATATAAAAATTGTAATCGTAATTTTCAGTTCTTATTCTTCTCGCTCATATTTTAGATATGGTTGGTTGATGAATTCTCAAAGTATTGACAGATAAACCTAATTGAATTAGAGTGGCAACATCTGAAAAAAAAAGATGAATTATTAAGACAAATGTTTTAGGATGAGCGAAAGCTTGGTTATGCAGTCATGAATAGAGTGGTAGCAAGAGGAGAAATAAGACAAACAGAACCTATCAAATTTAAACTTTTAAACTTTTAAACTTTTAAACTTTTAACTCTATTAAACTGAATTTATTTTTTTGTTACATAGTTGTAAATTTTCTCGCCTACCTACTTAGCGGAATATAGCTAAATTAAAATAATCTGGTAGAAAATTAAACCAAGCATCTCTAGAATAAACAGACAAATAAATCTTTTTCCCTCCTCCTTAAAAATCTATGAATATTGCAGATTATTATAGAAAATTAGACCTAAATTTAGGAGCTAGTCTAGGAGAAGTAAAAGCTTCTTATCGACGACTAGCAAGAATGTATCATCCTGATGTAAACCCAAAAGATAAGCACGCTAAAGATAAATTTATTGCAGTTACAGAAGCTTATAAAATTTTACTGAGGGTTGCTCCTGCTCAAGCTGAATTACCATATAATTTGACTCCAACATCAACAACGAATAAAAACTCAAAATCAGAAACTGTATCTCCAAGAGAAACAAAGGTTAGGAGAACTGTAAAACAAAAACAAAATCAAAATAAATCTCATACTTTAGAAGTAGAAAGGCAACTTAAACAAAATTATTATTTACAATTAAAGCATTTATTGAAATATAAGAGATATCCTCGGGCTATTGCTTTAGCAGAAGGTTTAGCTCAGAGAATGCCTCAAGATCCCGAAGTCCGCCAATGGCAAGCGATCGCTTATCAACGTTGGGGACGTCAACTTATCAATGAAAGAAAACTAGATAAGGCCAGAAACTATCTGAAGAAAGCCCTAAAAACAGATCCCCAAAACCGTGATCTTTGGGCAGAAATAGAATATGATTTTCATCAATTGGAGAAAATTTATTGATTATTTGTAGATTTGATTCATAATTGTCAGTAGCTGTAAAAATTACTTGAAAATTTAGCGGAGATAGAAAATCTATTAATAACTTAACCCAGCTTTTCAGATACATTAGATACATCATCTATTGTAAAAACTAAAACCATTTTAGGAAAAATGTAGTCTACTAATTCTGAAAAATACTGTAACTAAAAATCTCAACTATATTTGAGTATAAATATGCTAATTACTAATTTATTCTATATACTTATCATCGAGTATAATTTAGGTATTTTTTAAACTAGATTACCTCTTACAACTATTTAGCTTAAGCAACAGTAAAAGTTGTATAGACATTAAACTAATAAATCATTTAATAAATTAACAATGACAGACATAAATCAAGAATTTCAAAGAGCTCTCAAATTCCAAAGAGAGGGAAAGTTACAAGAAGCAGAATCAATATCAATATACATAAACATACATAATTCAGATAGTAAGCATTTTTTAGATACATTAAATACATAACCTATTGTAAAAAATAAAACCATTTTAGTAAAAATGTAGTCTACTAATTCTAAAAAATACTGTAACTAAAAATATCAACTATATTTAAGTATAAATATGCTAATTACTAATTTATTCTATATACTTATCGTCGAGTATAATTTAGGTAGTTTTTAAACTAGATTACCTATTAAAACTATTTAGCTTAGGCAATAGTAAAATTTGTGTAAACCTTAAACTAATAGATGATCTAATAAATTAACAATGACAGACATAAATCAAGAATTTCAAAGAGCTCTCAAATTCCAAAAAGAGGGAAAGTTACAAGAAGCAGAATCAATATATATAAACATACTTAAGTCAGATAGTGACCATGTAGCTTCCCTCATTAATCTTGGTTTAATAGAGCAAAGCCAAGGAAAACTAGAAGAAGCAACTCAATTTTATAAGTATGCTTTTCAAATAGATTCAAATAATATATCTCTACTATATCTTTTAGCAAGAATTACACAAGAGTTAAACCAATTAGATGAAGCTATTAATTACTGGCAAAAATTAGTACAACTAAAACCAGATGGTACTTTAGAATTTTACGGCAATATTGGTAATAGCCTAGTTCAACAGGGTAAATTTGACGAAGCACTAAATTGTTTTCGCGATGCCCTAAAAATATCACCGAATAGTTTTCAAGCTCATCAAGCCATCGGTAATTTACTGATTAGAAAAGAGCAACTTTTGGAAGCTAAATTAGAATTCAGTAAAGCATTAGAAATTAATCCTAATTATCAAACTGCAAAAATTTGGTTAACTTTAGTTGATAAGTTACTCAAAGGAGAAAATATAGTTTCATTCAATTATCAAAGCACCCCTATAAAATTTGAAATAACAGGCAAAAATCTAGCAGTAGAAATTGCTAATGTTGGTGGAACTTTTTATGAATTACCTGAGTTAGAGTTTATCCGGCAAAATCTAAAATCATCAAATCCTGTTATTGTTGATATTGGAGCTAATACAGGGAATCATTTAGTCTACTTTGCCAAAATTATGCAGGCATCAAAAGTAATTCCTATAGAGTTTCATCCAGATATTCTTGCTACTTTGAAGAAACATATATCAATTAATCAAGTTAGTAATATTGATTTATCTATATTAGGTTATGCTATTGGAGAAAATAGCGGTACATCTTTTATAAAAGAACATCCAGCTAAAGATTTATGTTTAACAGAAATTGATAATAATATCATTAATGGTACAAAAGTGGAAGTTATGACTTTAGATGACTTAATTAAAGAAAAAGTTGATTTCATCAAAGTTGATGTACAAGGAACAGAAGTAAAAGCTTTGACAGGGGCAAAAAATTTGATATCTATTTATCAGCCTGATATGCTAGTCGAAGTTGCCAAAAATCATATGAAGGACTTTCGCAAATTTTTAGAAGCAGTCAAATATCAAACTGTTAAAGCATTTGATCATGGAAGATATGTTAATTTCTATATTCAACATACTAAGTGACATACTCCCAAACAAACGTTATGGTAAATTCTGGGCTTTTCTTTTCCCGGTCCCGATACTCTCTCGGAAAAGAAGATACTATGAGGACAAGATCCTCGACCGCTCTATTTTTTTACACTTATGGCTACTTTTTTGGTTCACAGGTATTGTCTAGCGTCAAACATTCTTGACTTTGACGGTCAAAATAGATAGGCACTGTATTGCTGTTAGGGCAACATGAATTTTTACCCTCGAAGTAAAAAGCAATCTTTTTGACTTAAAACCTTCCCTGAATGTTAGGGGGAGAGTTTAATCGTAGCTTTGCTTAAGGGCGGGTTGATGTTTTGTACTTAGTATAAGCAAGTTAGCATAAATAAATCTAACTATAACGTCTATATAAACATAAGTATATATGGATAATATTTCGATTGAGTTAGGAAATTTATACATATATGTCTATGTCGTTTAAGGATATTGCTTACAAGTGAGCAAAACAGAAGTCTTTTGAAGTTGAGAATTGGGGATGTACCTCTAAAAATCAAAAACCACCGCAGAAGTGATTAGATTAAATGCAGATAGGCGGTATTTGTAAAAATTCAAAAACTAGAAATAACCTCTAAAGCTATTTCCCATTGCCTACTCCCAAAAAGTGGCAATATTTTAGATAGGAATAAAATAAGATTGATACATCTATGTTTTAGGGATTTTTTAGCTATTTCAGTTATTTCTCTTGCTAATACTGGGTTTAAAACCATTTTCAATGTAAAGAATTCTCAGGTAGTAGTCTATTTAATTATTTTGTCAAGTGCAACGGTAGTGGACTTACTAGTGGTTGTTAATCCCGAGCTACTATTACGCAAGTAGAGCTACCAAATCTAAAAGTATTATTATTTGGCTTATGTAGAAAATATTCTGGAAAAAGGCAATAGACATCGGAGCAAGATAATGTCAAACTTCTGATCTATTTTTGGATTTTTTTTAACTAAATATTAGGTAAGATGTAAAAGGTAAGAAGGTTTACTCCCCATTTTAGATGTTAGTAAATACCCCAATCTTGTTGGCATTTTATTTAACAATGTATAGAAGTAAATTTAGATAATAAACTAATGCCAAACTTAATTATCTGGCTAATAATATTTATAGTTAGCTTATTCGTTTTAATAAAAGCTTCTGACTTCTTTACAGATGCAGCAGAAAAAATAGGTATATCTTTAGGAATTTCTCCTTTTTTAGTAGGGGTAACAATAGTATCAATAGGAACTTCTTTACCAGAATTAGTATCATCTATTATAGCAGTTTATCAAAACTCCTCTGAAATTGTTTTTGGTAATGTTATGGGTTCTAATATTGCTAATATTTTTTTGATTATTGGTACTGCATCATTGATAAGCAGTCCTTTAAAAATACTATATGAACTAATTAATGTAGATTTACCACTATTTGTTGGTTCAGCTTTTTTATTAGGTTTAACAGTTTTAGATAGTAACTTTTCTATCAATGAAGCTATTATATGTATTTTAGGATATATTGTTTACGTCTTCTATGCAATCAGTAGTGGTAAAGAAGAACAGCAGTCAGAAACTATTGATACTTCACAAAAAAGTTTTCCAGTCAAACAAATAGTAATTCTGATTATTAGTTCATTATTTATCTTTTTTGGTGCTACTTATACAATTAAATCTGTTACTAAAATTTCCGAAATATTGGAAGTTGGTAAAGAGTTAATTGCTTTAAGTGCAGTCGCACTTGGTACATCATTACCAGAACTAATAGTTACCATTTCTGCTGCTAGAAAAGGAAACCCAGAAATAGCAGTAGGAAATGTTCTGGGATCTAATATTTTTAACTCATTAATGGTAATGGGAATACCAAGATTGACGGGTAAGTTAGAAATTCCTGATGATGTTCTTGATAGTGGGTTATTAGTTTTATTAGTAGGAACAATTTTATTCTTTTTTGTCACTCAAGATAAGCAGGTAACTCGTTGGGAAGGATTAATATTTTTCATATTTTATGGATGGTTTATTGGTAATATTTTTGGGTTGGTTTGACATCCTCTCAAACCCAATACTTAACTTTGTGCTTCTTTGAAAAATAGCCAGCAATAGCTAGTAATATAACGAGCACCTATACAACACTAATTACATATTCTTTTCCAAAATTTCTCAGCACTTTTTTGAGACATTCTTTTAAGCTACTCCAACTTTCATAGGCACTAATTTCAACCTACTTATACTTAATAAACTTCTACAATATTTTAATCAATTTTTTCTTGGGTGAGTAGGTAGCTAACCAAAATATCTCTAAATTTTTGTGTTTTCATTCTTCTAGTTTGTAAATCATTTTATTCTTAGTATGAATTAGGGCTTTATACATAACCATTACTGTAGTCATATATCAATATTGAGTAAATTTATCCAACAAGTAAATCAAAACTTGACTATTAATTACCCCTTTATTTGTCTGATCATATAATTGGTTTTTACAATTGATTTATTCCTATAGATTAATTATTTCAATTTTACAAATTTTTATGGTTATTATTTATGATTTTTACTATAGCAATTAGGAATAATTTCTGAGAATAAATTTTAGTATTTAAACCTGCAAGCGATCGCCAAACCTGAAAAAGATAGATAAAGCAGTTTCCGCAAGTTCTAAGGTACCCTAATACCAACTCTCTATGAAGCTGCGCTTAATATAAAGTAATAATATATGAACCTATCCTACTAATAAAATGTGATTAATCCAAATATATATAGTGGCACTATAATTTCTTCAATTACAAAAAAATACGCTCTCATTCTACAACTAGGCGACGATATTTACATTGATACCCAGCAAAAAACGCTATTTTTGAAAACGAAGTACATAAATCTTTATCCCTCCAAATCGGTTTCTTTTTAATTTTCCAAAGTATTTTGGGCAGCTGAGGTCTAATCCCTCTTCGATAACAAGCTTGTCTTTGTCGTTAACAATCAATACCTTTATCACTGGCCATAACTTAGAGCCCTTATGTGGATGGCTTCCTTTGTCAGTTTTCAGATTCATACTATCAATTTACGGGAATTAGCTGTGCTCTTTCATTGGCATTAGCGGGGGTAGTACAGTTAGCTACTAGTAATCCATTTTCTTCCCTCAAGGTATGAATTAAAATCCCCTTCCCTTTATGGCCATAAGCTACATCCACGGCTGTGTAACTCCAATTGATTAGTTCTTGGTTTTCTGCAATTCCTAAAATTAATCCTTGTAGGTGTTTGAGAGTTCCATCTTTTTCCTAACGCTTCAGCCATTTATGTGCGCAAATATTGGAAGCCCAAATCTCTCAACCTCTTATTTAGGAAGTGAGAAGGGTATGATTGTAAATATCAAAATGGAGTATAAGGCATACCTTTACCTCTTTTTTCTGGTGAAAGAGGAAAAATATCTTTAAATAACTTTCATTCTATGTCACTTAATTTTTAAAATCTATCTAGCATCTTATTTGAATTTACTATAACTGAGTAACGCTTATCATAAGTATCATTATTTTACTATTATTGGGATAGATTCTTAACCAAAAAATATCAAGAAACTGGAGATATTAAATTTTTACCTCAACATAGAATTCTTCCTTCTCAGCTCAATAGTGAAGAATTAGTAATCTTAGTAGAAATAATGGATAAAAATAATGATGCAACTAATGAGAAGTTATGGGAATTACTGGAAGTAGGCACGGGAGTAAAAATAGGAAAAAGTACAATCATTGGATAAATGAAAAGTTAAACTACAATCTGAAAAAAACATTGTATGCACCTGAAAAAAAATATTCAACTCCAATATAAGAGAGTAAAATTTTGGGAAATAGTCAGAGGAATAAAGGCAAATAATTTAGTCTTTATAGATGAATCAGGAGTAAAAAATTGGGAATACTTCGATTATATTCTAGAGCCTTAAAAGTAAAAATAGCTAAAGGAAAAAAACTAAAAAACCAGGAAAAATATCTTAATTATAGGAGCTATATTTTTAGAAAAAGTTTTGGCAAAAAAAATATTGATGGAGGAGTATATGGAGTAATTTTTGAGGTTTTTATAGTTAAATAAGTAGTCCTATTACTGTGGAAGGGAGCTTGTGTTTTCATGCACAATGGGAAAATATATTTAGGATAAATGGTGAGAGAAGTTATTGAATAAGTTAGAGTTAGTCTGTTATTTTACCTCCTTATTCACCTGAATTTTCTCCAATTGAAAACTTTTGGTTAAAAGTGAAAGCTATTCTAATAATAGTTAAAGCAAGAAATTATAAAGATTTAATTATTGAAAACTTTTGGTTAAAAGTGAAAGCTATTCTAAGAAGAGTTAAAACAAGAAATTATAAAGATTTAATTGATGCCATTACCATAGCTATATTAAAAGTTAGTCAAAAAGATATTCGCAATTGTTTTACCCATTGTTGTTACTGTACTTCATAGCTATAGAAATTGCTATGTATAAGGAAACTATTAAAAAAATTAATGAGGCTAAAGCTCAAGAAGGAGGCGTAATGATTTTCGGGTATTGTTATCCATCTCAAAGCAATTCGTGGTTTAGATTGAAGTATAGGCTAGGAGAAAAAATGCTGAGGAACTACTCTCTTCCAGCTAGAAAATCACCTATTATGTAATAATATATATTACATGATAGGTAATAAAGGATAAATCATGATTAAATATTTAGGGAATAGAACTTTTAGATTAGGCGATCGCCAATTATATTTAGAATTATGACCATAATTGTGCTACAAATTTCAACAAGAATATTTAAGGAAAAGATTATTAGCAATTATAGTTATTTTAAATAAGAATGAGATACTATTTTGCACGATAATTATGCATAATTTCATCAATAAATGTATTGACAGGTGAATACATTCTAGCTCTTTTTAATTCACTAAAATCATATTCTTAGTCATTTAAATCAGGAGAGTATTTTAGGAAAAATAGTAATTGATGACTCCCTGCTTCTACTAATTCTCTAACAACCTTTTTTCGTAATTAATGTTGAATTATCCGTGTAGCAGTACACTGGGAATTTTTAATGATGGTAATAAATGTTGCTCTAACTATTATTCAAATACCACGGCATTTAGGGTTTCTTTAAATATAATTAGTGCTATTAAATGTTTTTCCTTTTTTCTTCTCCCTGCTACTAAATTTTCTCTTTTACCTCGTTTTCCCTCTTGCTCACCATAAACTTTTTCCCTTTTTTTTACCAGGCATAAATACAGTCTTAATTGTCTTAAGATCCTGATAAATCAATAAATACAACGCTTTTATTTCCAATTTTTTTAATGAAATTTTGAGGGAAAGCTGATAATATTTTATTCTTTCTTCTCTATTTCTTTCCCTGTAACGAAGTTGTTTTTTTTCAAGGAAAATTCATTCTTTTCAAAGCATAAAATATAGCTGTTTGATTAACTCCAATTTTTTTTTTAGCTTTGTATGCCAATTTAAACTCTGAATTTAGTTTGACATCTTTTTCTAATTCTTTCCAATCTAATTTTATTCGACGACGCTTTACCTTAGTTGCTTCCAATTTTTGGCGAGATGACCATCTATATATCGAAGCTATGCCTATCCCAAATACATGAGCTGCTTCGGTAATAGTACCACCATTTTCTACAAAATTTATGACTTTTTGTCTGAAGTCTAAACTGTAAGACATAGTTAGAAATAGTTTCTAATTGACTTAAAATTATTCTACTTAATTTTTCTCTCAATCTTAATTAAAACAACTATAAATACTTGTATGAAGGAAAAACTAGAACAGAAGTATTAGATTTATTAGATTGTCATTATCAAACTTTATCTACTTGAATAGATAAATTTTTAGAAGGAGGATTAAAGAATTTATTAGAACTAATCACTCACCAAGTATCATCAAGATTAAATATAGAGCAGAAACAGGAATTAAAAATAATGATACTGAAAGAATTACCCAGAGATTATGTGGTAGATAGAAACATTTGGAGGGGTAAAATTATTAGTAATGTTATTGAATTAAGATGGGGAGTAAAACTGAAAACAACGAGAATATATAAAATTTTAAATGAATTAAATTTATCAGCTCAAAAAGCCCATATAAATTATGCTAATGCCAGTCAAGAACAGCAAAAAACATTTATTTTAAGTCTAAAAAAAATTGGCATCTAAAAAAGAGAAATAAAAAATAGTATTTTTTGATGAATTTGCTGTTTATGAGTGCTCAAGTATTTTTTACAGATGGGCAGAAAAAAAATACAGCTCCCGAAGTACCGAGTAATGAGAAGGGATTTATAAATAAATTGAATGGAATGATTTCAGTTGATGCCTTTACAGCTCAAGAGTATTTAAAATTAAAAGAAAAATCTAAAACAGAGGAAGTTTCGGATGACTTTTTACAATGAGCTCAAGATTGTTTAACAGAAGGATTTGATAAATTGACTATTATTTTAGATCTGGACTCGACAGATAAAAATAAAATGAAATCTCAATTAAAATTTCATCTCATTAATGCTCAAATATTCAGATAAAATTGTTGTAGATTTTATTCATACTCCAACATATTCTCCTAATTTTAATTGAGTTGAATATATTATTCATCTTTTAAGACTTAAACTGTTGTATCACCTTTCCTGGGATGTAAATATTCAACAAGTTCAAGGGTATATTAGAAAAATTTTTCCAATTTAATCAACTTCAGACACCTGAACAAATCAAGAGTATAATACTGAAGCCAAACCTTTACTGAATTTACTATGTGTTGGTTGAGGTTATCAAGCAACAAGGTAAAATTAACGAAGTAATTAACAACTATAAACTAGCCTTAAAAATTCAACCGGATTTTCCTCAAGCCACTGTAAATTTGCAACATCTATTAGACTGATAAATTCATCTTATAACTTTGTACATTCAAGGCTATTCAAAGATTAACTTTAGAAGAAAAAGTGAAATATTTCTTTTGTCTGAATCTATACTTGAATCTATATTATTTATTATTTTTCAATAATTATTTGAGCTTTTGTTTATTTCAATTGGCTTAATAGCATTAAGTCTTTATTCCTTAGTATAATATTTTATATTTTAAATTCTTACCTAAAATTAATGTATTTTATAATACGACACTTTGAACGGACACAGCTTTCTAGTTATAGTAATCCTATCTCAAGGGTAAGAGAAATGGGTTGTTTTAAAGCAGGAGGCAGAGAGCACTTATAATGAAAGAATAGGAGTTGAAGCTATTTTTTTAAGAAAGCATATGATTTAGGATTACTATACAAACAAGAAGATGCAAGAAGAAAACTGAATATCCAGCAAAAAAATTAACTAGATACCAGTTTTAAAAGTGTACAAAAACACAAACTATTAACAATATAAGCTTTGCCCTAAGTAGATAAGGGTTAAAACTTGTTACTACTTAACAAAATAAAATTAACCTCAAGTTAACTTTAGATAGTAACTTGGAGTCAACTTACAAAAGTTAATATAGTGAGTGTTTTTTTTGGATACCTACTTAACTTACTACTACCCTATTCAGTAATTCATAAAGAAAAGAGTTGATAAAACCTAGTGCTACCGAACCAATTAGAGCACTCCAAAATCCCCAACGTAAGCGAAATCCACTAACCAACCAAGCTGCTAAACCAAAGATAGACATATTCAGAAGTAGAGTAAAAAGAAAACTTGAAAGAACAATCTTAATAGGGAAAACTACAGCAACTAAAACTGGACGAACTAAAGCATTTAAAAATCCAAAAACTACCGAAGAAATTAACGCGATTTTAAAATCATCAATTTCTACTCCTGTTGGTAACTTAGAAATAATAAATAAACTAACAGCAGTCACAAACCAAAGAATCAAAAGTTGTAAAATACTCAT

Protein sequences of DBSCAN-SWA_4

>NC_008312|1843886:1944867|1844522_1847486_+|WP_011610923.1|DBSCAN-SWA
MPLLTERTIEVGQKLQGFEVKAITDLKQQRMVAYQLEHIKTGAKLLHLYSEDAENLFSISFPTPPPNSTGVSHILEHSVLAGSKKYPVREPFFEMLKMSPATFINAMTGPDCTYYPVSSKVKQDLFNLAEVYFDAVFHPLLTENTFKREGHHLAPTDKENPTGELKFTGVVYNEMNGAFSDPEQRLDSIANQSLFPDNIYGLESGGNPQNIPELTYKDFRDFHSSYYHPSNAYFVFYGNISTPEYLEFLAKKLEAFERQKPNININPQSRWSEPRFKEDSYPISAADETTQKTYIMIKWLVGDSTDSEEWVALDILSRILLGNEAAPLKKAIVESQIGQDLLGSGVDSVGKEVTFHLGIQGSEPNQGEAFSQLVIKTLKEIAEEDIEPSIVEAAFQQAIYQHQEIGSMYPLRMLFRVMQTWIYSNDPLKFLHISDRLAECKQRYLEKPRYFNNLIREKLLNNPHRLTLVLKPDKEWQSNYDKAVVAQVEQVRSQLTSEELERIATEATELEIESGTPNSPEEIAKLPQLQVKDLPDKPEHIPTDVEELDGQVTLLRNHVLANGVNYLQLDFSLRGLPEDLWLYLSIYIDALRKLGAGEMNYEQVARGIASYTGGISFQSLLRTSTKDAYHSVRGLRVTIKTLDEQIEPALELLHNMIFAVNPRDTARLREVMIQSYSQSNSDLIYNGIYTAILRASAGMTSEAKISEIVNGLPQLELLKKVCDRFDEHGANLMSKVETIRDYVANQPLTASFTGSDNAYNVVKKTLSEWGHQQKQQEGDTFGSRFEPVYNMREALAGPVQVAYCVQTMPAPHFSDERAPFLRLGTHLLGLGYLFTEVRLKGNAYGAGCRYSGLGKVISLYSYRDPHVSRTLDVFAGLIDYLKDVDWTQIDVDRAIIATIQDDSPVLRPEVATSLALERHLIAQTAELREERYQRTLKATVADVKETLLDVFTAGMERSNVCVMSSREKLEEANRSREADPLTISDIM
>NC_008312|1843886:1944867|1873335_1873719_+|WP_044136462.1|transposase|DBSCAN-SWA
MITTPKGTEIVDVIVGEKGPVSDVKILRKQQDKFDKKQKFQGDKAYEGVERTTTPKKKPRKKEMPLEIKEENQEKARKRIFVEHVIRLIKIFGIARERFRLKDNNYQKVILTICGLVRLRIGSFILA
>NC_008312|1843886:1944867|1889023_1889311_+|WP_081432407.1|transposase|DBSCAN-SWA
MNVAKIFSQGSKPSPVGTTRISATETSTQRGPKPNANLIEVVNSIFYILYSDCHWRSLPQDLPPWQTVSTKFSKCNGYVVWEQINHTLWRETRVQ
>NC_008312|1843886:1944867|1890143_1890284_+|WP_155994326.1|DBSCAN-SWA
MTQQKVMEKLQLEIETLKLSRETDSKTFSKPLSTDLLKKIRQSKIL
>NC_008312|1843886:1944867|1901361_1902057_-|WP_011610959.1|DBSCAN-SWA
MNPKDKTNIATRSAILVENICFNWPNGSQVLRSCSLKVPKGQFWMLLGTNGSGKSTLLRLLTKLLSPQSGTINFEGKIGFVFQNPDHQLVMPTVGADVAFGLVAEKLSKLQVRNRVKDALSTVNLLELERRPIYALSGGQKQRIAIAGAIARNCDILLLDEPTALLDPDSQLDLLTQVQSLVKNRGITALWVTHRLNELDYCDGGFLLDKGQVVAQGNPEFLKQRLIKDSF
>NC_008312|1843886:1944867|1857686_1858649_-|WP_011610930.1|DBSCAN-SWA
MSNCPQCQAEVNKGDNFCRNCGYALHDSLTGDKPQGFENIRETSAHAATWEHNIKEQLVQMLESFKSQLQELTQKQNNNTASLEAEREEINQINNENSKLQEELQELIQKQNNNTASLEAGREEINQINNEISKLQDELRPIKKLISLFGEWFKNNPEYLPLSTTIDPQVKLQTSTELNTTREVEEEGKYQLPLSEEEQLLKDYKDEEKRTVLSQNAITVSAATESIDNSRLGIGKSVLEKKRRGNYWILKQGSSQYLVPSDTIKINEYSIDTLKNLFECQGVNSEGSKGKFELLKPAKVSSIGEEKWQLSEPGKLEFIG
>NC_008312|1843886:1944867|1885698_1886535_+|WP_044136472.1|DBSCAN-SWA
MGTGFKVERNRKNQKIISPKAFFRDTLTKLWEDIEDKTDVFVILLDDLENLAAVSDILMTLKSALSTESLMETKILVGLASTSTSWLEITSVQKHHPLSRYFLSRVELTSLTEKEVQETIRESLAGTEVSFTQEVMQNIFEYSSGHPFEMQLLCYHLFSNHLSRIVEIDIWEKALQATVRDVGNAIFEKWCSDLSIDEAKVLRILAENENSVALEKLATTFETENLMIPPNYSVEEVLKSLLQRKLISRDIYGNYIVKDLMFRTYLITHLNYNSTGSH
>NC_008312|1843886:1944867|1899851_1900091_+|WP_011610957.1|DBSCAN-SWA
MFHYGISPKNFDKEQKNKLRSDEILGHHIEGKFAQQQKRSHKKVIAKLSKTSTTAIAITFFTFLVINLSTLLKEAFSLF
>NC_008312|1843886:1944867|1853301_1854318_-|WP_011610927.1|DBSCAN-SWA
MKPDNYSSELTNSVRVTKTLETLPRGWISLSEDELIEAYNYAPRVLSRKAIKVSKIDFRGWRYSNSEVLLGEERNGNYWVMVTEKGCYWLLPKANFRINSFNKDTVKSLFKFNGSLSEDAREFILVKLAKVSLTPGGDQWRLEERGVLDFGGNSQLSRLQSELEGVKEEREKLESELRLARDERDRFASQVAELAYDRLQKTLAKLEEGDRWRSNLTERLERLEQAGALQEQRCSNLEADYFQRLAQLKSELSEKLVQLQSQLSKLEESEINNIYQLQEITHKQKNNTTYLKAVGAEINKINSQILKLKEELQRLLEGELRPIKELVSLFGGWLRNSP
>NC_008312|1843886:1944867|1866981_1867239_-|WP_044137207.1|DBSCAN-SWA
MTIALDRLPKQQSQKILCFYGNNTRKMQIARVSSVENKYWERTVFPGERFLFEATPEAELEIHQTQENGEIKSESFSCKGLKVDE
>NC_008312|1843886:1944867|1907659_1907941_+|WP_011610962.1|DBSCAN-SWA
MTELLAVEEINQRISQISDWKLEGNKLKYIKTVKNFVEAINFVNKLVAPAEASQHHPDLEVSYNKVTIILTTHNSGGLTEKDFKMAKTISGLS
>NC_008312|1843886:1944867|1943206_1943395_+|WP_155994328.1|DBSCAN-SWA
MSAQVFFTDGQKKNTAPEVPSNEKGFINKLNGMISVDAFTAQEYLKLKEKSKTEEVSDDFLQ
>NC_008312|1843886:1944867|1862475_1863948_-|WP_011610933.1|DBSCAN-SWA
MGLYLIGIGGTGAKCVEAVAKLAAIGLFTEEPIKVLFVDADETNGNLARARTSISLYKKTYDLIPTGDKKDCGWMKSKIESFDHWSPFAQEKELRTFFNYNTIKQKQPTLAHLFDVLYTKEEREANLDVGFRGRPAIGAAVMSQVDLDRLEQEPWGRLIEEIQGDTGGGKEAKIFLCGSIFGGTGASGLPTIARLIDNKLKKIKVRDRVQTGCLFVLPYFGFAPTPGENPDGVYARSEQFLLNTEAALRYYVTQGQEIFDQVYLLGNQNLSRVNFSIGKDSQRNDPHFLELYAALAARNFWRDSSTAKGSVILMTRQQSGTISWDDIPDKAEVQPELVNATRFAFTWLAEIAPELEEAKKEKNARFQRLAPWMMEFYQTGSKSGETKPDFSDVDQQEAIGIINNWCEDYLGWLYSLHQCEGDNIALFQADAFPPNKKLAGNELPNLIVGDSRDKGKKSRDTVKKLKDGLKATPPGGTIGLAKSVYMASRI
>NC_008312|1843886:1944867|1851087_1852776_-|WP_011610925.1|DBSCAN-SWA
MKSELNDYTEKYNQLQAEFQESQQEGREMKSELNDYTEKYNQLETEFQESQQEGREMKSELNDYTEKYNQLQTEFQESQQEGREMKSKLDDYTEKHNQLETELQESQKERSPEIAEKLNNLTKQVVAGNQEQEVQKSKLLIIETNLQKVLEQLSQQIYPAENLESGLLEILENLNEQVGVRIQSQLSTIETNLQKCWKKLSQESSQDELLEIISQQVSSLTERLDNIKQSSSPKEISPPPSPIGLNLSWQEAELAATYNASPDSLLEIAITVSETEASMNQSIQEVVFETNRRGNYWIISQESDNYLIPKQHIKLNQFNKQMFTRLFESSSFQEDSSKLLLLKPAKVSPINLGKSWQLSEPGIVKWIQIKMSSSDTPTPTPEPTPERTPEPTPEPTPETTPEPTPEPTPEPTPEPTPEPTRILPPLPPEEANFVELYNSSQSWRSKKPTTVAKVNDSSNTVILEKKRFGNYWILSEESGDYLAPRQKANINPDNNEDVQGLFECYGDSSGELKKFQLLKLAKVEPTEDRGKWKVLELGVLKFESRKLKDEDNSENENQTKES
>NC_008312|1843886:1944867|1894821_1894950_-|WP_155994649.1|DBSCAN-SWA
MILRGDRYFSLPEIIKVCEDQNVQYVFGFSSNAVFRIKLIIY
>NC_008312|1843886:1944867|1900635_1901181_-|WP_011610958.1|DBSCAN-SWA
MSRPLRQTILLVDGYNVIGLWSRLREICNFHGLETARRDLIEALVNYSASQDLNTQIVFDSQYQYTPTTKEIITDKLSVHYTEFGQTADTYIEKACASLRTEVHLSRSRLIVATSDRVQRLTVIGYGAEWMSSQQLAHDVESAANCVRSRCQRNKRASGRFLASYLDPESQKRLAELRMEK
>NC_008312|1843886:1944867|1916944_1917445_-|WP_011610966.1|DBSCAN-SWA
MKNSILTDLQIPEAAKFPEPIPTNLKNLVEKGLKLVKEIVNDDPPGHFLIANPGEIFNPENHEPVPSCEPSGQIVYTTYPGYSVNNRIIGESLKAFVFTEPNKQPEGQEEQPFENNQNHQQPNSIENEQQSPSNQQLKPTSNHQSPVPQTSENNQNNQQPSSIENQ
>NC_008312|1843886:1944867|1886637_1888122_-|WP_052845755.1|DBSCAN-SWA
MIGHTLELDDLKKISSPKKIVALFEKLGFNFQIEHLDIEQLELPSYCRETIDNTYKIYNPNQEELQVFLLELRQEKFKTNYKEQERIITISQGILRNKNNFLLIATKKYNKLIIVAPHRRENQNIKISIKWWLIDCQNPNYYDTYWLENVAINNCEPTEELTNKHNSEGSYDPDIEPPTGTFTEDSIQLYYKQVNSFARLHPEEEIHLAHQIDGLLALEKIYEKLEEKLNRSPNEIEWATEAKMSKWELCDRLEQGRRAKNQMVTANLRLVTSVAKRYQNRGLDFQDLIQEGVIGLLRATEKFDHTKGYKFSTYGIWWIRQAITRAICDYSRIVRLPVYLYETISQIKKIVKQISIECSPLTAEEVATRMEMTTEKLQFIIECAQETLSLDYPINKGENIIYKEMIKFNGETPTKYVFENCLQEDVESVLKTLTERERNVLQMRFGLDDGQEKTLKEIGDTFNLTRERIRQIEAKALRKLEDPKRNHILREYIH
>NC_008312|1843886:1944867|1882705_1882909_+|WP_044136466.1|DBSCAN-SWA
MVEGSTKKQLKSSKSNSLDLVEESNSLTNSCNQQNIRDKKHKIYQIICADVAHSLKGEFLNIGGSNE
>NC_008312|1843886:1944867|1885360_1885747_+|WP_011610950.1|DBSCAN-SWA
MRAQSARTTPLPSPISVFFLLKYSSVPEHKFLSIYSFQLACHPVRITGYGNVELAKRTLTKGVFDFIEKSATAVEDLVSAVQRAIDTRKEKIRRVGNPFTPMTGLEPTVFGGRWEQDSKLSAIGKTRK
>NC_008312|1843886:1944867|1930018_1930708_+|WP_011610972.1|protease|DBSCAN-SWA
MKSPIKAVQTSSYYGDVSFRTPPPDLESLMLKERIVYLGLPLFSSDEVKRNVGIDVTQLIIAQLLYLQFDNPEKPIYFYINSTGTSWYTGDAIGFETEAFAICDTMSYVKPPIHTICIGQAMGTAAMILSAGTKGYRASLPHATIVLNQAKTGARGQATDISIRAKEVLVNKTTFLDILSKNTGQSVEKIAKDTDRMLYMTPEIAKEYGLIDQVLASRKELPKPLPANV
>NC_008312|1843886:1944867|1843886_1844102_+|WP_071820548.1|transposase|DBSCAN-SWA
MIQSWTYFLSINDDYKVYTYLIEDCDHKVNKTAMTRVEGEKCRRCYYLTRLHRKTLCYSKSIDMLCKSIVC
>NC_008312|1843886:1944867|1908789_1910424_+|WP_011610963.1|DBSCAN-SWA
MIQLNTLKLFQELTETSELLIIEQLLDIGVALSDTYNLGELLNLILSKSREITCSDAGSVYLVDEVNFKERKLVFKVAQNDSIPELAFQEIALPIDFKSLTGYVALTGHTLNIPDAYNLPKDIPYKFDESFDEKTGYRTCSVLILPVQKQNQEIIGVLQLINRKVQPDVVITKENAKELTKAYSKWEQRILISLASQAAISIERNNLQENIENLFEGFVKASVQAIEARDSCTSGHSERVAKLTVGLCQEVNIITNGVFSGTYFSNEQIQEMRYAALLHDFGKIGVPEGILTKRKKLYQEQLELIKQRFSVAQRTLEMESAQTKYEYLLRHLSGTYQSHTQESCPLCQKIENLDLELKTAITQLNNYWQTILIANEPKVLAEEPLKQLQQISLYTYKDTDGQIKPLITSEEMAQLTVPRGNLTPEERRAVEAHVTHSYEFLKQIAWTKNLQNIPEIAYGHHEKLDGSGYPRGLKKNEISLQTQIIVIADIYDALTAGDRPYKQGLPVEAALRIMRSEAAENKINSHFLELFEQKQVFSILGHSK
>NC_008312|1843886:1944867|1871193_1871847_+|WP_011610939.1|DBSCAN-SWA
MKNQQLIIFTRYPEPGTTKTRLIPVLGAKGAANLQFHMTETTVIKAKKLSNMMALLVEVRFAGGNLQLMKNWLGVELNLKYQKQGTGDLGERMARAFESAFYQEMESVVIIGTDCPSLTVDIMLEAFAKLTEYDVIIGPATDGGYYLIGLKKIIPELFQGINWGTSEVLSKTMAIAQNLNLDIHYLPKLSDIDRPEDLEKLQFEIHQDLRKDTIYST
>NC_008312|1843886:1944867|1902053_1902320_-|WP_011610960.1|DBSCAN-SWA
MFTIDIIVKYTPVPFSIQRKSAEDAESTYEQIVESIRSGNPQILELTCEKIPEKKIAVVMSEVSGVQISQKSGAAATGRPPGFVTVAQ
>NC_008312|1843886:1944867|1854402_1855686_-|WP_011610928.1|DBSCAN-SWA
MWKSIHSWKSTYSLLLSLVLISGSFVACVQLEPEIPPSTSTTSIPLNPDQENLKNSFDDVQKTNNELAAIANNNEEEIKNLNYEKQAIFNQLNQFKNIRRTVIFSFILLVLFTVLLLFYISLLIWQIKQNNAVNKPSNLDTQELVYEVDYKVEDAYYKLEKMSKLWDAETKKIKSQIYYLQQNQQVKTPGNNVDNKKLIVQVVNDKIGEIYRQLQQEIDQRWDIKLRNLQNQINQLQQNQQLKTSDNNADNKKLIFEAVKEEIHGQLQQEIRKRLDIELRNLPNQINQPQQNQQLKTPDNIAGGLPNLEFMLIYKEDTRSLSENAIEVSEADRSMVQPRISSTQAVIIQKVRRGNYWILNEADIDYMVPRHNIKINEYNSKTVANLFECQGYRPEYSGFQLIKPAKVSAISKGETWQLVERGILQFD
>NC_008312|1843886:1944867|1919536_1919836_-|WP_011610968.1|DBSCAN-SWA
MDKSFEVVVAIDFGTSRSGFAYKFKESDVSVFRDLWPDNPMSYPKTATYLLLSSTGEVEAWGYTAMKKLAQFRAQGTAKDYYFTRNFKMELHSGKKDES
>NC_008312|1843886:1944867|1890998_1891178_-|WP_155994327.1|DBSCAN-SWA
MMQRQRQARYQRGIKPQMPKRLGKRKKKPGSAIKVSVSRFQQEGCFAWDQGKYRRLVVG
>NC_008312|1843886:1944867|1926210_1927449_-|WP_011610971.1|DBSCAN-SWA
MKVNLRSALNDTNIDASQSLSQRQVALSISVMANQLERTVPLNLCLILDHSGSMEGRPLETVKQAAVQLVEKLKEGDRLSVVAFDHQAQVIVPNQMINDSASIKGKINKLRASGGTAIDKGLKLGIEELNKGRKESISQAFILTDGENEHGDNDLCLKLAKLATDYNITLNSLGFGDDWNQDVLEKIADAGGGNLSYIQQPEQAIEEFSKLFNRIKSVGITNSYLQFYLMPKVRLAELKPIAQVAPDTIELPVKKEGNGFIVRLGDLMKDIERVVLVNTYIGQLPEGKQAIAQLQIRYDDPAQNQEGLLSESILVEANFMEKYQPQVNSQVQNHILALAKYRQTQIAETKLQQGDRAGAATMLQTAAKTALQMGDTGAATVLQTSATRLQDGDKLSEMERKKTRIVSKTILK
>NC_008312|1843886:1944867|1919853_1921656_-|WP_011610969.1|DBSCAN-SWA
MEKFLPNKKNWFQHLAEGFSDFFWGTRSARMSSETLRINNDNLIEYYEKRDSIQQQIQIAQIQLKTVMEERNFQFQYEQGNLNRQFQAQQGELNRQLQTELGTINRLFQAEEGKLNRELQTELARLNREHQIQEGKLNRENAHQLELFRAQLQIFLQEKQKDLQLQLKEIDATLARELKAIDLQNNLTVIRQQRRLNNWPLTLDDEQIKEIVKSDNLLILFVPPILKYDRAGAGANSQPNTFPDIEQGLNRRLRAFLEKYKQTGRKVDFLTGAWMTKALSGEGAFKTIFSGLKSKPMLVINTLVERTYYHLEYSYWSQNFPEPYIDSLPKEDPLSWLELLYFAVKERLLKWEKQRNQEKIETGTTEEFDADWGEEVVKKFLADLQLIKREKRLLERGQDPNNLPNRNYTVLDSDKETFSRFIAIQVSLLIGRTADAYFLLDVPPQERKRPLLPELLPNLLEEIPSEEREKIIEYLVYFYQSLYQQLGEEESAWVPEMLIDFASSLIYLDNKFWAKEQIEKSVESWLLMRGIKSLDQVSNLEVMKYVLVSGDDEYLDRLNQFILLLGRENYVIIAETLLDTWRKLKIKGCIGVDGHGQTLF
>NC_008312|1843886:1944867|1869678_1870758_+|WP_011610938.1|DBSCAN-SWA
MLDALIIISFVFAGAGIGFYSIELLPPNVLLEVTNIEGLRSVLSAFTSLIGFVVGLVFQTTYRRVEIKFRQMPVDLLLTRAIGLIIGLLVANLMLAPLFLLPIPDEFSFIKPLVAVLASVMLGFTGVNVADTHGRGFLRLINPNSLDAVLVAEGTLKPSTTKILDTSCIIDGRIESLLKTGFLEGQILVPNFVLQELQLIADASNDQKRVRGRRGLDILNRLKELYPSQIQIHFADYEEIPTVDAKLVRFALEINGTLLTNDYNLSKVASLQKVPVLNINDLTQAVRPSYLPGDTIEIKIRKEGKEPSQGIGYLDDGTMVVVESGSGYVGDEVRVIVTSSLQTSAGRMIFARTQESAIA
>NC_008312|1843886:1944867|1944501_1944867_-|WP_011610979.1|holin|DBSCAN-SWA
MSILQLLILWFVTAVSLFIISKLPTGVEIDDFKIALISSVVFGFLNALVRPVLVAVVFPIKIVLSSFLFTLLLNMSIFGLAAWLVSGFRLRWGFWSALIGSVALGFINSFLYELLNRVVVS
>NC_008312|1843886:1944867|1917667_1919488_-|WP_011610967.1|DBSCAN-SWA
MIAKYIRLIKDEALKEIKNSTSGELKDQEIRWCLSIPAIWKNEDKDLMRRAARKAGLINSSDDEAERLFLVLEPEAAAIFCQEEDKNALTPGNKIMIIDCGGGTVDITVHKLVKDGGLDEVAPGTGGPFGSIYVDKSFQEYLTEKLSAEMVKGFHDQDPVGYLKMMEEWERTKCNFDPETSGDVIYFNIPTRLYNFISKRKAKILEQLADEQNGDDENIHLSYSTMENIFRITVHKLVKDGGLDEVAPGTGGPFGSIYVDKSFQEYLTEKLSAEMVKGFHDQEPVDYLKMMEEWERTKCNFDPETSGDVIYFNIPTRLYNFISKRKAKILEQLADEQNGDDKNIHLSYSTMENIFRPTLDGLVSTVKNQFKELGDEEVDIIFLVGGFSTSPVLRQRIKKEFGSKAKKIVMPPRPGVAILKGAASFGVAPGIIRARRSRLTYGVSSSREFNQFKDTIISQKQQSDNPENWENCLRVYKNNNDFLNWLLNNFDIQYSNHNHEQEKQQINSLKNALKNPKKLLEKFYNIYLMIVEPKKRYNQKHKQELKETVYLLNQKIQSQEILINELKRENEKLRKLKSSLLSKLSDRDRDTSNTITSDESRPQRDV
>NC_008312|1843886:1944867|1878802_1879288_+|WP_011610943.1|DBSCAN-SWA
MTQATDSGFVQPYKGDPFVGHLSTPISDSDFTRAFIGNLPIYRPGLSPILRGLEVGMAHGYFIVGPWTKLGPLRDSAVANLGGLISTIALVLIATICLSAYGLVSFQGKSPEGADPLKTSEGWSQFTGGFFIGAMGGAVVAFFLLENFELVDSIFRGLFNS
>NC_008312|1843886:1944867|1882999_1883473_+|WP_044136467.1|DBSCAN-SWA
MLIDYLNLGKQKMKPIDIEKLIGEVELLSRHRLPSNIKMEVKIQENLKGRTILGNFDQIKSVLFELIRNSTKVLHKPDSKIQIFASYENDGLITLSIKDNGSSIEDGLKKKLFKEIVDSESGSDIGLYIINRIIHQIGGDLKLTSSEEGTTITLFFS
>NC_008312|1843886:1944867|1922202_1922877_+|WP_011610970.1|DBSCAN-SWA
MVSSDYYKILNVHPTATQGQIRQAYRRLVKLFHPDTNTEVANHERIISINEAYEVLSDPQQRKSYDQQLNQNYQRYRNISQDYYKHNKRRQNIDEHLQRWINHVYRPVDTIIIQILKPLKNEIDDLAADPFDDQLLESFQDYLETSRGLLKKAHNLFSSQPNPSNFAGVAAHLYYCLNQVSDGIEDLELFTLNYDDYYLHTGQELFRIADKLRQEAQAAIKGIF
>NC_008312|1843886:1944867|1942928_1943162_+|WP_044136478.1|DBSCAN-SWA
MILKELPRDYVVDRNIWRGKIISNVIELRWGVKLKTTRIYKILNELNLSAQKAHINYANASQEQQKTFILSLKKIGI
>NC_008312|1843886:1944867|1930922_1931513_+|WP_011610973.1|DBSCAN-SWA
MPIGIPSVPYRLPGSQYERWIDIYTRLGQERIIFLGQEVTDGLANRIVAYMLYLDSDDPNKPIYLYINSPGGSVTAGLAIYDTMQYIKADVITICLGLAASMGSFLLAAGTKGKRLALPNSRIMIHQPMGGTRGQATDIEIEANEILRVRSELNNMLAERTGQSLEKIEKDTDRDYYMSAEEAKEYGLIDQVIEER
>NC_008312|1843886:1944867|1852806_1853136_-|WP_011610926.1|DBSCAN-SWA
MPNCPVCNTEYQQQQVNFCLKCGWYLRLYSNSGDEVLEGSGFSSSDALQKVEKWAIQKLHVLKKQESQLKQLRAKYEELQAELQQSQQERSRLKSELDDYTEKYNQLQT
>NC_008312|1843886:1944867|1935766_1937014_+|WP_011610975.1|DBSCAN-SWA
MTDINQEFQRALKFQKEGKLQEAESIYINILKSDSDHVASLINLGLIEQSQGKLEEATQFYKYAFQIDSNNISLLYLLARITQELNQLDEAINYWQKLVQLKPDGTLEFYGNIGNSLVQQGKFDEALNCFRDALKISPNSFQAHQAIGNLLIRKEQLLEAKLEFSKALEINPNYQTAKIWLTLVDKLLKGENIVSFNYQSTPIKFEITGKNLAVEIANVGGTFYELPELEFIRQNLKSSNPVIVDIGANTGNHLVYFAKIMQASKVIPIEFHPDILATLKKHISINQVSNIDLSILGYAIGENSGTSFIKEHPAKDLCLTEIDNNIINGTKVEVMTLDDLIKEKVDFIKVDVQGTEVKALTGAKNLISIYQPDMLVEVAKNHMKDFRKFLEAVKYQTVKAFDHGRYVNFYIQHTK
>NC_008312|1843886:1944867|1938099_1939044_+|WP_011610976.1|DBSCAN-SWA
MPNLIIWLIIFIVSLFVLIKASDFFTDAAEKIGISLGISPFLVGVTIVSIGTSLPELVSSIIAVYQNSSEIVFGNVMGSNIANIFLIIGTASLISSPLKILYELINVDLPLFVGSAFLLGLTVLDSNFSINEAIICILGYIVYVFYAISSGKEEQQSETIDTSQKSFPVKQIVILIISSLFIFFGATYTIKSVTKISEILEVGKELIALSAVALGTSLPELIVTISAARKGNPEIAVGNVLGSNIFNSLMVMGIPRLTGKLEIPDDVLDSGLLVLLVGTILFFFVTQDKQVTRWEGLIFFIFYGWFIGNIFGLV
>NC_008312|1843886:1944867|1872804_1873305_+|WP_155994325.1|transposase|DBSCAN-SWA
MYKVSQMNPTLEYIYNHPKETKRIIGITYEQLIKLIAKAQIIESEKKKAIAKTEKRLIKAGGVRKKNLTKEEEIILTLFYLHQIPTFQTLGINFGISESSANNIFHYWIDILRELLPASLLEQVKKKENELEWVKEILTELELIVDSTEQSRERPSEYKDQEKYKI
>NC_008312|1843886:1944867|1884749_1884935_-|WP_052845875.1|DBSCAN-SWA
MITVAWKKRALPIYWKILSHKGASNLTEQKSVIRPVLKLLKVHKIILTAPSNSTVFSCAIG
>NC_008312|1843886:1944867|1875928_1876612_+|WP_011610942.1|DBSCAN-SWA
MSSISIIIPVLNEVGTIAQTISTAQTGKNVEIIVVDGGSNDGTIEVVKSLNIKLIYSLPGRSIQMNFGAKLATGNILLFLHGDTFLPLNFDELLREIIVQPNIIAGAFELGIRGKKRILRIVESIVNWRSRYLQMPYGDQGIFLSAQVFEQIGCFPEIPIMEDFELIQKLRKRGRIGIISKPVLTSDRRWQKLGILKTTLINQVIIIAYLLGLPPKTLAQWYRSHLK
>NC_008312|1843886:1944867|1904237_1905296_+|WP_011610961.1|DBSCAN-SWA
MTVAVGRPQSQRGAFDVLDDWLKRDRFVFVGWSGILLFPCAFLSIGGWLTGTTFVTSWYTHGLASSYLEGCNFLTVAISSPAYSMGHSLLFLWGPEAQWDFARWCQIGGLWSFTALHGAFALIGFCLRQIEIARLVGIRPYNAIAFTGPIAVFVSVFLMYPLGQSSWFFAPSFGVAGIFRFILFLQGFHNWTLNPFHMMGVAGILGGALLCAIHGATVENTLFQDGEAANTFRAFEPTQSEETYSMVTANRFWSQIFGIAFSNKRWLHFFMLFVPVTGLWMSSIGIVGLAFNLRAYDFVSQELRAADDPEFETFYTKNILLNEGIRAWMSPADQPHQNFMFPEEVLPRGNAL
>NC_008312|1843886:1944867|1867439_1868708_-|WP_044136459.1|DBSCAN-SWA
MVKRPVGNYCIPSSAYVHIPFCRRRCYYCDFPISVVGDGKKGDNFSPIQEYVEVICQEISTTKSFDQPLKTIFFGGGTPSLLSVGQLSRILDALEQKFGIVANAEISIEMDPGTFDLEQVQGYKFLGVNRVSLGVQAFQDDLLQVCGRLHNVSDIYKAVNTLHQAGIINFSIDLISGLPHQTLEQWQISLLSGIAISPTHISSYDLVLEKVTAFGHYYKPGHAPLPTDETAAEMYRIAQQLISISGYEHYEISNYAKQGYQCSHNRVYWENHPYYGFGMGAASYLEGQRFTRPRTRKKYYQWVLSFQDHSLESQGINASNQDFLLETLMLGFRLAQGINVLTLSQQFGQKTVEKLLIYLQPYQKLGWVEFINQKGVATPFSDNQKLPIEGHLRLTDPEGFLFSNTVLSTLFSKISNSISMKC
>NC_008312|1843886:1944867|1879464_1879581_+|WP_011610944.1|DBSCAN-SWA
MTGSYAASYLPWILIPVVTWLMPIIVMGLLFVYIESDA
>NC_008312|1843886:1944867|1934395_1935022_+|WP_011610974.1|DBSCAN-SWA
MNIADYYRKLDLNLGASLGEVKASYRRLARMYHPDVNPKDKHAKDKFIAVTEAYKILLRVAPAQAELPYNLTPTSTTNKNSKSETVSPRETKVRRTVKQKQNQNKSHTLEVERQLKQNYYLQLKHLLKYKRYPRAIALAEGLAQRMPQDPEVRQWQAIAYQRWGRQLINERKLDKARNYLKKALKTDPQNRDLWAEIEYDFHQLEKIY
>NC_008312|1843886:1944867|1880410_1881139_+|WP_011610945.1|DBSCAN-SWA
MKIFVYHTPEETPTENMPDCAIAVDVLRATTTMATAIYAGAEAVQVFSDIEELMTVSEKWSADKRIRVGERGGKKVEGCDEGNSPLNFTSETVKGKRLFMTTTNGTRCLKRIQNAKVVLAAALVNRRSVVEYLKENQPETIWILGSGWEGSYSLEDTVCAGAIAHSLLAETNSLSDENVGNDEVFGAMSLYLQWQDKLHELMNHASHGQRLQRLECYEDLKYCSQIDILDVLPMQKEIGVLS
>NC_008312|1843886:1944867|1855866_1857600_-|WP_052845753.1|DBSCAN-SWA
MSGSLVACVQTDPNTILTSPSITSSPLNPDQGNLDQENLKNSFDDIQKTNDEFQTLLDDFIKDIAAVREGSKNRESVNSSKVNEKLIQLEEKVNTYKNQISQIRNQENLEQNFNSINQNISNIKEITEKLKGGLGKDKIGEVQLNLQIITNPEVSYFGRLGPDTQSKINESLTENSKQLKAKIIDLGQVTGLPSSVTLDKDDDKELARKIADLEARNNELAAIAKKNEEEIKNLNSEKQEIYNQLNQFQSRLKLETFVVIIVLVIAVFLSGLCVYIWQDWRRIKLLLKRYNKAYTNTKQPNNGVNQTGDLDTQELVYEVDDKVEDAYDKLEKMSKIWENEAKKIQSQIYYLQQNQQVKTPGNNVDNRKLIVQVVNEKIGEIYRQLQQEIDQRWDIESRNLQNQINQLQQNQKLRTSDNVAGVHRESRITTNHLTSQVTPVPQMNPQIPTHQYFGSSDLQLISMYQHDARSLLKNAIEVSETEQSIDQRRLGGGQGAILQKVRRGNYCILNEGGVDYMVPKNNIKINEHSLETVKNLFECQGYRSGYSGFQLIKPARVSAISRGETWQLVELGVLQFY
>NC_008312|1843886:1944867|1911567_1913487_+|WP_011610964.1|DBSCAN-SWA
MSKTFWYCLILSPAVLGATLVASSYALATENKQTNTVIQPQAATTENISINNNIDIQEPDLLAQVTATNSTNSVGNTPATTIRQINRYGREGRNLRRPGLRNITNNRKPIKGQVTSVSQLSDVQPTDWAFQALQSLVERYGCIVGYPDGTYRGNRALTRFEFAAGVNACLDRVMELLQAAIEDTVSREDLAILQRLQEEFSAELAILRGRVDALEARAAELEANQFSTTTKLRGEVIFALVDNFEDQGKYGAFGDTIQDEDQTVFQYRVRLNFNTSFSGEDLLFTRLQAGNAQAFNQKIAESEGQQTFNILDRTDDTLQLDKLFYKFPVRDNIRVTIAANKVSWYDFVPTLNPYMEDFDGGSGSLSAFGQRNPIYRLGGGKGLGVEYDFGCKDQYACTYSPFSVSFGYLAAEGENPSQGKGLFNGDYAALAQLTFTPIRNFQVGLTYNKGYFGPGNFGFDDGAATGLGDNGSLNSGFVGTGIANSVYGLNAGLNDRRPGSVNINKSVSTNAYGVEMSWRAADWVTINGFGTYLDGKLIGKGDFEIWTYGATIAFPDLLKEGSLAGIVVGREPYLNDLELPSGLDSGLRQDMSWHLEAFYKYQLTDYISITPGVTVITNANQDDDNDELIIGTIRTTFQF
>NC_008312|1843886:1944867|1849483_1850875_-|WP_011610924.1|DBSCAN-SWA
MNSTKITRWKIPLLLFMLIGITTACRPKTYNDLSCDVPLTKGQSPSLDAPPGPINISLNIDGSESMPGYLTNGASRYIKTIQLLDRTFSISDLVEYYRVGGPEKQKISRSKFLEAIKERFYYEDRVTSNLTGAIAPQKEGKELLVLITDLYQNQGDVTAVNKKIRQHYLNKEGYAAGILAIRSEFNGKVYVVGSNRDNFNFPYNTEGKPIEKFRPFYVIFLGPYKHILYYFEKLKRDGGELIKNSEFTIFSPNNIINDLSVMSELKNPGEPISGLKRPFSLNNGKVAIEFPKRKEFELLEIIPNFSKEIPIEYKVNLPILNEYTLPPSANSIKAKISESKYFDESTTEFISSEAIMAKKLFNSMQFSNWEVGKNRDLSYTNTIKPNELPQANIYLFKVDVVANGLGEQDWWQNWNCEDRDCENDGSKTHNLEHFLQGLKSLTNDLMENNPIVLARLCYGIQKN
>NC_008312|1843886:1944867|1914920_1915883_+|WP_011610965.1|DBSCAN-SWA
MRIAHNITELVGRTPLVQLNSIPKAEGCLAKIIVKLEGMNPAASVKDRIGVNMINVAEREGLIKPGKTTLVEPTSGNTGIALAMVAAARGYKLILTMPETMSMERRVMLRAYGAELVLTPGSEGMKGAITKAQEIVDLSSNGYYMLQQFQNPANPEIHSKTTALEIWEDTDGKVDILVAGVGTGGTVTGVAETIKARKPEFQAIAVEPSNSPVLSGGKPGPHKIQGIGAGFVPDVLDTKIIDEVIQVPDSEAMVYGRRIAKEEGILSGISTGAALCAAIEVGKRPENDGKLIVMIQPSFGERYLSTPLFQELGPTLAEVR
>NC_008312|1843886:1944867|1884105_1884465_-|WP_011610949.1|DBSCAN-SWA
MGIEAMFKDYKTGGYNLESAKANETRLNNLILLIAISYTISSFKGQEIKNKGVQEYISRTNERGRKERRNSSFCLGLSSVYWAINDDLMWKLVENLMSLNPHKLLYYRRGIKAMNKVVN

Homologous phage analysis in the prophage region

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_071820548.1|1843886_1844102_+|transposase	IS1 family transposase	NA	NA	NA	NA
WP_011610923.1|1844522_1847486_+	hypothetical protein	NA	NA	NA	NA
WP_011610924.1|1849483_1850875_-	hypothetical protein	NA	NA	NA	NA
WP_011610925.1|1851087_1852776_-	hypothetical protein	NA	NA	NA	NA
WP_011610926.1|1852806_1853136_-	hypothetical protein	NA	NA	NA	NA
WP_011610927.1|1853301_1854318_-	hypothetical protein	NA	NA	NA	NA
WP_011610928.1|1854402_1855686_-	hypothetical protein	NA	NA	NA	NA
WP_052845753.1|1855866_1857600_-	hypothetical protein	NA	NA	NA	NA
WP_011610930.1|1857686_1858649_-	hypothetical protein	NA	NA	NA	NA
WP_011610933.1|1862475_1863948_-	hypothetical protein	NA	NA	NA	NA
WP_044137207.1|1866981_1867239_-	DUF1830 domain-containing protein	NA	NA	NA	NA
WP_044136459.1|1867439_1868708_-	coproporphyrinogen III oxidase	NA	NA	NA	NA
WP_011610938.1|1869678_1870758_+	PIN/TRAM domain-containing protein	NA	NA	NA	NA
WP_011610939.1|1871193_1871847_+	glycosyltransferase	NA	NA	NA	NA
WP_155994325.1|1872804_1873305_+|transposase	DDE transposase family protein	NA	NA	NA	NA
WP_044136462.1|1873335_1873719_+|transposase	transposase	NA	NA	NA	NA
WP_011610942.1|1875928_1876612_+	glycosyltransferase family 2 protein	NA	NA	NA	NA
WP_011610943.1|1878802_1879288_+	photosystem I reaction center protein subunit XI	NA	NA	NA	NA
WP_011610944.1|1879464_1879581_+	photosystem I reaction center subunit VIII	NA	NA	NA	NA
WP_011610945.1|1880410_1881139_+	2-phosphosulfolactate phosphatase family protein	NA	NA	NA	NA
WP_044136466.1|1882705_1882909_+	hypothetical protein	NA	NA	NA	NA
WP_044136467.1|1882999_1883473_+	sensor histidine kinase	NA	NA	NA	NA
WP_011610949.1|1884105_1884465_-	hypothetical protein	NA	NA	NA	NA
WP_052845875.1|1884749_1884935_-	hypothetical protein	NA	NA	NA	NA
WP_011610950.1|1885360_1885747_+	response regulator receiver protein	NA	NA	NA	NA
WP_044136472.1|1885698_1886535_+	hypothetical protein	NA	NA	NA	NA
WP_052845755.1|1886637_1888122_-	sigma-70 family RNA polymerase sigma factor	M4SMP8	Cyanophage	3.8e-30	31.9
WP_081432407.1|1889023_1889311_+|transposase	transposase	NA	NA	NA	NA
WP_155994326.1|1890143_1890284_+	hypothetical protein	NA	NA	NA	NA
WP_155994327.1|1890998_1891178_-	hypothetical protein	NA	NA	NA	NA
WP_155994649.1|1894821_1894950_-	hypothetical protein	NA	NA	NA	NA
WP_011610957.1|1899851_1900091_+	hypothetical protein	NA	NA	NA	NA
WP_011610958.1|1900635_1901181_-	NYN domain-containing protein	NA	NA	NA	NA
WP_011610959.1|1901361_1902057_-	energy-coupling factor ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	5.8e-21	33.6
WP_011610960.1|1902053_1902320_-	hypothetical protein	NA	NA	NA	NA
WP_011610961.1|1904237_1905296_+	photosystem II D2 protein (photosystem q(a) protein)	A0A0E3FX82	Synechococcus_phage	3.1e-183	88.0
WP_011610962.1|1907659_1907941_+	4a-hydroxytetrahydrobiopterin dehydratase	NA	NA	NA	NA
WP_011610963.1|1908789_1910424_+	HD domain-containing protein	NA	NA	NA	NA
WP_011610964.1|1911567_1913487_+	iron uptake porin	Q5GQG9	Synechococcus_phage	9.4e-13	43.6
WP_011610965.1|1914920_1915883_+	cysteine synthase A	A0A1X9I5F1	Streptococcus_phage	2.7e-85	57.4
WP_011610966.1|1916944_1917445_-	hypothetical protein	NA	NA	NA	NA
WP_011610967.1|1917667_1919488_-	Hsp70 family protein	NA	NA	NA	NA
WP_011610968.1|1919536_1919836_-	heat shock 70kD protein 12B	NA	NA	NA	NA
WP_011610969.1|1919853_1921656_-	hypothetical protein	NA	NA	NA	NA
WP_011610970.1|1922202_1922877_+	J domain-containing protein	M1PHB4	Moumouvirus	3.0e-06	38.8
WP_011610971.1|1926210_1927449_-	VWA domain-containing protein	NA	NA	NA	NA
WP_011610972.1|1930018_1930708_+|protease	ATP-dependent Clp protease proteolytic subunit	NA	NA	NA	NA
WP_011610973.1|1930922_1931513_+	ATP-dependent Clp endopeptidase proteolytic subunit ClpP	A0A223W000	Agrobacterium_phage	1.5e-46	52.2
WP_011610974.1|1934395_1935022_+	DnaJ domain-containing protein	NA	NA	NA	NA
WP_011610975.1|1935766_1937014_+	FkbM family methyltransferase	NA	NA	NA	NA
WP_011610976.1|1938099_1939044_+	calcium/sodium antiporter	NA	NA	NA	NA
WP_044136478.1|1942928_1943162_+	winged helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_155994328.1|1943206_1943395_+	hypothetical protein	NA	NA	NA	NA
WP_011610979.1|1944501_1944867_-|holin	phage holin family protein	NA	NA	NA	NA

Sequences of DBSCAN-SWA_5

Nucleotide sequences of DBSCAN-SWA_5

>NC_008312|1962193:2023112|DBSCAN-SWA
TTTATGGTTTATTTTTTTTCTTTGGCCTGTCAATTCTTGACCCACCTTGATAACCTTTATCTCCTTGAAATCTTTGTTCTTTATCAAACTTTTTTTGTTGTTTTTTGAATAAAATTATATCACTCTCTGGACCTCTTTCTCCTACTATTACATCAACTATTTTTTTTCCATTATCTGTGATTATTATTTGATTTTTTAACCTATGACTTTTTTGCTTTCCTGAGTAATATTTTTTCTGCTTTCCATCATTTTTTGGCCTGAATATATCCTGTTCTGTACTATCAACTATCAATTCTATTTCTGTCAAAGCTTCTTTTATCCATAAATATTCGTTTTTTTTCCCGAGAATTCCTCTAGTAAACTAGATGGTAATAATTCCATCAAAATATCGCTCCAAAGCCTGAAAAATATTATTTGCTGTTGATTCACTAACTCCAAATATTGCTCCTAGCAGTTGAAATGTTGGTACATGATGCAAATAATATAATGTCAAAATTATCTCTTCCGCTTTGCCTAAAGACTTTTTTCTGACTCCTCCTGCCTTAATTAATCTTTTTTCTTCTTTCTTCGATCGTCTGTCTTTTTTTGTCTTCAACTTTTTGAGCATTTTCTATTAATTTTATTAGTTGTTTATCTGTAATACCAATAATCCTTTTTGTATATGGATGGATGATTATAAATATATTCTAATACATTATTCATTTGGGGACAGCATATATATAATTGGGCACTACAATTTTACCTTAATTTCTATTTTGGAGAGGTCTATTAGTAGAAGTTTAAAAAAACTTGGGTTTACTCGTAAAAAAAAACATATGGTTATCAAGAAAGAGACGAAATAGAAAGAGAAAAGTTGGCCTTAAAACTGAATCAAATAGACAAAAAAGATATTGTTTATGTAGATGAAGCCGGAATAGATAATAATAGATAATAGAGAAGATTATCCTTATGGTTATGGATTTAAAGGCATTCATAGTACCAGGCATGAAGTCCGGAAAAAGAACTGAGAGAGTTAGTTGGATTGCAGCTATAAATCAATCAAAAATGTTTGCTCCTTTAACATTTACAGGAAGTTGTAATCGTGACTTGTTTGAGAACTGGTTGGAAAATTGTTCCCATACCAAAATTACAACCAGGGCAAGTGATTATATTGGATAACGCAACGTTTCATAAATCAGTTTATATTGAAGAATTAGTGGCCAAGCAAAGGTGTGAAATCTGGTATTTACCACCATACTCACCAGATTTTAATAAGATAGAACGTTGGTGGTTTGTGTTATAGCAGTCGAAGCAAAGATTAGGACATAATGCTCGAAAAATTATCTAGGAAAGATTATGCCTTCTCCTTATAGCTATGACTTAAGACAAAAAGTTATTAAGGCCATTGATGGTGGGATGAGTAAAACTCAAGTAAGTTCTATATTTAAGATTAGTCGTAATACCATCAATACTTGGTTACATAGAAGAAGAGAAACTGGGGATATAAAAGCAAAAACAGGTTATCAAAAAGGATATAATCCCAAAATACCAGACTTAGAACAATTCAGAAAATTTGCCCAGATTAATGGCAGTAAAACTCAAAAAGAAATGGCTGATGAATGGCCAGATAAGGTAAGCGATCGCACTATAAGTAAAGCCTTAAAAAAAATTGGTTATACAAGAAAAAAAAACTTACGGTTACAGAGAAAGAGATGAAGACAAAAGAAAGAAATTTCTGGCCAAAATTCGCGATAAAAGGCCGGAACAGCTAGTGTATATAGATGAATCAGGTATGGATAATAGAGAAGATTATGGTTATGGATGGAATGAATTGGGAAAAAGATATTACGATTTAAAGTCAGGAAAAAGAAGTCTAAGGGTAAGTATTGTAAGTGGTTTGTGTGAAGGAAAATTAGTTGCTCCATTAACATTTGAAGGCTCTTGTAACCGTGTAGTTTTTGAAAAATGGTTGAGAGAAAAATTGTTGCCACAATTAAAAACAGGACAATTAGTAATATTAGACAATGCAAGTTTTCATAAATCCCAAAAAGTTAGAGAATTAATAGAATCAGTGAATTGTGAGCTTGAATATTTACCACCATATTCTCCTGACTTAAATGAAATAGAACATTATTGGTTTCCAATTAAAAATCGAGTCAGAAAGTCAGAAGGAACAATAGAAAATTTTCGCATTGAGAGTTGATTATGCTGTTAAGTTAACGTCCTAACCTTTGCTTCGATTGCTATAAAAAACGATCTGCAAACAAAGACTGAAGAAATTTGATCATTTTAGAGACTGTGTGGATGCAGCTTTTATAGAAAATCCTCAAGTTTTTCCGTAGTGGTGAAAGATATCAATTATTAATATAGAATATAGTTGCTCTTTGAGGCGATTCTCTCACTCGAGAGGCTTCGCGAATACACTCCCATAACACTGTGATTCTTTTGTTGTCAGTTAAATCAAAGTGCAACGCGGGAGTCTATAATACCAAATTTTAATCCGAGCTGCCATGCTATAATTATTGCCTGGCAAGGATTTTCTGACATCCTTATGTCACATTATTTTTTCAGGCATGGCATAAAACTTTAAGGTAGTGCGATTGCGCCTCCGTTCCGTTGTCACGATCGCATAGAAAAAATGTCAGTCATGTAGCAGGATGTATACTACATGAATGACATTGGTAGTATGTAAAGATGCCAGCGCTCATTGCTATATGTGGATTAATCGTATTTAATTAGTGGGATAGGTTCATTGTCAATAGATTAATAGACATCTCCAAAATAGAAAATAAGGTAAAATTATCAAAACCATTTATGTATACAGTCTCCCAAATGAATCCAACTTTAGAATATATTTATAATCATCTAAAAGAAACAAAAATAATTATTAGTATTACTTATAAATAGCTAATAAAATTAATATAAAATACCCCAATAATAGAATCATAAAAAAAGATTAATTAAAGCAGATGGAGTCAGAAAAAATAATTTAATAAACGAAGAATAAATAATTTTAACATGATTTTATTTACATCAAATACCAAGTTTTAAAACATTAGGAATTAACTTTGTTATAAGTGAATCAAGTGCTAATAATATTTTTACTTACTGGATAGATATTCTCAGAGAATTACTGCCAGCAATTTTATTAGAAAAAGTAAAAAAAAAGAAAATGAATTGGAATTGGTAAAGGAGATATTAACAGAATTATAATTAATTTTAGATAGTACAGAACAAGGTAGAGAAAGACCAAGTGAATATAAAAACCAAGAAAAATATCAAATATGAAAAAAGAAAAATTATACTTTTAAAAATTAAATAATAACGATACCAAAAGGAACAGAAATAGTGGATGTAATAGTAGAAAAAAAAGGTACAGTAAGTAATGTGAAAATATTAAGAAAACAACAGGATAAATTTGATAAAAAACAAAAATTTTAAGGAGATAAAGCTGATGAAGGAGTAGAAAAAACTACTACACAAAAAAAGAAACCAAGAAAAAAAGAAATGCCACCAGAAATCAAAGAAGAAAATCAAGAAAAGCCCAAAAAAAGAATATTTTTAGAACATGTAATAAGATTAATTAAAATATTTATACTTCCTAGAGAAAGATTCAGATTAAAAGATAATAATTATCGAAAAGTAATTTTAAAAATATGTAGTTTAGTCCGACTAAGAATTGGCTAATTTATATTAGTAAAAATCATCAAAAACTGAGATAAAAATAATAAATCAAAGTCTAATAAATATTTAAATTAGTAACACGAAGTATCTCTGATAACCATAAAACTGTACAAATTAACTATCTTCAATGTGAGCTAACGCTCCACTAAAAATAGTTAGTATAAGCGTTTGAGTATTTTTGGAGATGTCTATTGAGCTCAAAAATGATTTATCATATCTGTTGATAGTCTAAATTTTTTCCATCCTTTACTTGATTTTATCTTCAACTATTTAGTCTAAACTCCAGTCAGAAGAGTAAAATTCATCCTAGCTGCGACCTCTGGAACCGACATTAGAACGATAAGTGAACAACTATAACTACATAGAAGGCAAGTGAGACAGTGGTGAAAAAGGTCGTTGGAGGCTTCTGAACAACTGGCAATTGCTGAAACTCAACAGGTGAGCGACAAGAAGTTAAAGACACTGATAGAAGACATTCTCAGTGATGCTCCCCGACCAAGAACAACCAAATTTTTCTCCGTGGAGCAAGTGGTCCAAATCGTAGCATAGGCCAGTGAAGACCCAAGACAATCTCAAAGACCAGTGAGTCATTAGACTCCCAGGGAGCTAGCAGAAAAAGCCATAGATAGAAGAATTGTGGAGAAGATTTCACCTCTTAGTGTGGGGCGTTTTTTAAAAGGAAGGGACTCTACAACCTCATGGTCATCGTTACTGGTTAAACTCTAATCCCTCTGACCCAGTAGCTTTTCGCGACCAGGTTAAATCTATCTGTCAGTGATATCTGTCGGCCCAAGAATTACTCGAAAAAGGAATTCATCTGATTAGTACCGATAAAATGACGAGTATCCCAGCTAATGAGAGAATTGGCCCCACTCAACCAATAGAGCCAGGACAAGTCGAACGCAATGAGTTTGAGTACATTTCCCTAGGTACTCAATGTCTACTGGCCAACTGGCACATAGCCAAAAGACAAATCATTACCCCTTCAATTAAGGCCACCCCCAGAGAAGTTGATTTTCTGCAACACATTGAACAGACTATCCATACTGAATTCTGATGGAGGATGAATTTTTCGGATTAGAGCAACTCAATACTCATAAATCTGAATGATTAGTCCGTCAAGTGGCTCAATGTTGTGGTATTCAGACTGATTTGGGGGTAATACAGAAATCAGGTATTCGAGACTCTATGGTAACTCGTGCTGCTTTTTTGTCTGACGAGTTTCACCAGATTCGCTTTGTTTATATCCCTAAACATACTTCTTGGCTGAATCAAATTGAGTGTTGGTTCTCTATTTGGGCCAGGGGTTGACTCCGGCGTAGTAGTTTCTCTTCCACCTCAGAGCTCAAGCAGAAGATACTAAATTTTATTGACTATTTCAACTGTACTCTAGCCAGACCTTGTTGCTGGAAATTTCAGGGGTTTGAGCGAGGATGATTAACCAGATTCAGATTTATGCTCATACTGGCTCAAGCATCAAACTCTATGCCGATCATTTTTAGCTTGGCTATTAGACCATTTATTTTACAAGTGCGATCACACTTCTGAGTATTCCATCTCAGGAAGAAGGCATCACTTCTACTGGTCACTTATTTCTCCCATCCTGTACTAGAGGTGGTAGAAAGCGAGATAGCTCAAGTGTCAGGTCATAGAGCCTATGCTCAACGCAAATGCTACTCCCAAGCATCTCATAGAGGAGCCAAACTGACCATACCGCCCCCTAAAAATATAGTAATATGACATCTAGGCAATTGTAAGAGTCCACCTCATACCAGATATGAGAACCTCAGAGAGATTCGTAGAGTAGGATATAAAAAGTGGAAACGTGAGAGGAGATAGCATAGAAGTTTTCTGTCAGAAAACTCCTGTGTAATGGTTGAAAGTAATATTTGGGGGTAAGTTACAACAACGCAAATTTGACAATCAGGCAGTGGAATTGTTCATACAATGTGCTATACTTAATCGTATGATACAGGATTGTAAGCCAAAAAGCTACAAAGTAGAATTCTAATCAACTTCTCCCCACAAGAGAAGTTAAAGTCGCAACATTTATGCAACAAAGCCCCAAAAAACTGTAAAGCTAATTATTAAGGTAAAGAACTATCAAATAGCTTCAGTTGAGATTGAAATTATTCCTAGCTGTTAGGCACAGGGGTAGTTCTAGCAAGCCAAAGCTCAAGGACGGTTTGAGATTTATTATGCTGCTGGAATTTCTTGTTGTATGTTGCAAAACTTTACCCTAGCGTGATCTTGGCCTGATGTGTCCGTTTTTTTATCTCGGATTGCTTGTGCGGGAATAATTAATTGACATTTAGGATAAAATATACTGAAAAAAATAACTAAAAAGTTGCCTGATAGGCGGGGGAAGCTTTAAACCAAATTTTTTACTATTCTTTTAGCAGGTAAGTAAATCCAAACACCAAAGCATCCTTTGTCGGTGTTAGAAATCTTTCTCCATGGCCTATTCTTGGAGTTAGAAGGATGTTAATCTTTCCTTTTTTCTGATTTATCATTGAAAAATAATTTTCTATGCCTTCCCAACTTTGGCCTTATGTTAGTCCAGGTATCCCAGATGACTTATTTGAACGTTTACCTGGCATTCCCATGAGTAAGCGAGAAGTTCGCTTACTATTAATATCTTATTTACGATTACAATCAGATTCAGTAGTATGGGATATTGGCGCAGGAACAGGAACCATACCAGTAGAAATTGGCTTAATATGTCCTCAAGGTCGAGTTATTGCCATAGAAAGGGATCAAGAAGTAGCAAGTTTAATTAGGAGAAATTGTAACCGCTTTGGAGTGGAAAATGTCACAGTAATTGAAGGTAATGCTCCCGAATGTCTTGATAGTTTAACCGATGCACCTAGCCGTGTTTGTATAGAGGGAGGTCGTTACATCAAAGTTATATTGCAAGAGGTTTGGAAAAAATTATTACCACAAGGTCGTATTATTGCTACGGCTGCTAATCTAGAAAGTCTTTATGCTGTTTCTGAAAGTTTTGCGGATTTACAAGTTAGGAATATAGAGGTCGCCCAGTCGGCTCTGAATCGTCTGGAGACTAGAGGAGTATATCAAACCTTCGCAGCAGTTAATCCTATATTTATTTTGAGTGGAGAAAAAATAAATTAATTTTTGCCTCAGCTTCAAGTAAAGAAAATTAACTATCAACAATTTTCATAATTCCTGAGGTACTTAGATTCCTTTGTTACGTGAAATAATAGAGTAGCTAGGGACGTTCATGCAACGTCCTGATGTTATAGTAATTTGAGCAACAGCGAATAGAAAAGAAAAAAAACAACAGGTTAATAGTGGTGGAGAGTTTGATCTCCTCTCCAGCTTTTATGTGCGGGTATGTCTACCGAGGCTAATCTCAAGTGTGACGTTTTGCTGACTGCTCCCAAAGCTGCTGAACAAACCTAAACCTAATAACTTTAGAGATAGATTATATTATGTCCGGTAGTATCGTTTATTTAAAACCTGAGGGATATGGCTACTTTGCAAGTCCTTGATAAACTATGAGTAGGTCACCAAAACTTTGTTCCATGAAAGTGACGATATAGCTGCTGTACTTGGCCCAAATATCAAACTTCCTCTCTGCTTTAAGGAGACATCATATTTAGACCAGTTGCTAATCTGGTACTTGGACTTGGAATTAGACTTACTCATATCTAGGTTAGTGCAGTTTTTTGTGCTATGAACTGTTATTTTGACCCTCTTTTCTTGCCTTGTTCTAGCTACCAATAATAATAAGTGAGACCTCGAATGAGCGATATTGCTACGCAACGCTACCACGAATGCTATTTCATTAAGTTTATACATCGATCATCAATCATTAGACTTCTCCGAAAATAGTCAAATCAATACTATAACTATCTTAATTGGAGCGATCGCTATTTCAAGAAGATAGTTGATTTTTACAGTCTCATAGGTATTAGAGATAGTTAGTATTAATATATAGCCCTAATTATAGTATTTTCAACCAAGAATTTTTTCAGAAATTATTGGCAAATTTATTAAGACAAAATAACCGTCCCTCTTCCCAGTATTACAAGTCCACAAATAGTCATTATTATTTGCGTATATTTATCAGAATTTAGCCTGAATCTTTCCTGGGCTACTCGAAATATTTTGAGTAATCTAATTATATGTTCTACCAAAATTCTTTCAGATGCCAGCTCTTTATTTTGAGACTTTTCCTTACTGGTTAATTCTTGAATAGGGGGCTTTTTTTTAGGCGTTTTTATTGCTGGTTCTCCCACATAAGCTTTGTCCCTGGTAAATTTTTGTTCTTGATGGAATTTTTCTTGGATTTCACGAAAAAAATTTATCTCACTTATTTGGCCTAGTTTTCTAGCTTCGATATCAACAATATCTTTACCATTGGTTAACACAATCACCTAACTTTTTCTTGTATGACTTTTTTTCTTTCCTGAGTAATATTCTTTTTGTTGTTCAGATTTTTCTAGCCTTTCTATACCCTGTTCATAGCTATCTATGATTAACTCACACTCTGTTAAAATTTCCTTAATAATTTCTTTGTCACTTGAGTTTTTTTTACCTGTTCTAGGAGACTTGATGGTAACAACTCCCCAATTATTGGAAACCAATAATTAAAGATATCATTGGCAGAGTTTCACTGACTCCAAATTGAATTCCTAATAGTTGAAAAGTTGTCAAATGTCTTAAATAAGTTAAGGTTAAAATGATTTGTTCACAAGAACGATAATTTAGGTGATCTACCACCACCAGAAGCGATTATTCTAACTTTTTTAGCTGTGGCTATTTCTCGCTTCTTCGATACAAAGTTTTTTTGCTTGTTTTAATAACTTTTCTACCCGTTCATACTTGATACCTAATAAAATTTCTGATTCTTGTGGAAGATGTCTGAATATACTCAAGTATATTAGTCATAATTTGCCTACAAAAATTTCTATTTTTTATTACTCTATCACAATTTATTTATTTTTCGGAGATGTCTATTGACTATCTCTTCCATCTGGGATAAATTTTCACTCGTTTTGATTACTTATAGATTCATTAATTAGCGGCCAGAGTTGTTCGGCTGGTTGTATAAGCAATCCCTTTGATCCTATTCCATAATCCTCCATCTGGTGCTTTCTCCTGGAGTAACATTATTAGTTTTGCCTGTAGTTACTCACAGAGAAATCCTTTTAGTCCTAGATGTTGATAGTGACTATCTACCAATCCTTCTTGACCCTGATGATTGTAGCAACGTACAATTTTCTTAATGGCCTCCAAACGATAGCCTGTAGCTGAAGAAACTTCTCTCATTGTTTTTCTCTTTGCGCTTAAATATCAGGTCTTTTCTATGGGATCATTAGATAGCTCAGGAGTTTCTTTCCAGTTCATCTAAACTTAGGTATTTTTAAATACTTAAGCGTCTTAGTATAATGGCGCTCGCATTAGTGTTGGATAAAAATATCACTCCAGGCAATTTTTTTTCTATTATTCTATATATATAAAAACGATATTACCAGACATGATATTACTTTTGCCTGGTGCTTCCGTTTTTCGTCTCGGATTACCCTTAGAGCTAATAATTAAGTTAAATGAATTATAACATATGTTTAAAAACAAAACAATTAATAAGTAGAAAGATCATGGGGGAGGCTTCAAACCAAATTTTTCGGTAAAATTAAAATTTCTAAAGTTTATAATATTATGTCTTGGTCTCGAATAGTTAGTGGACTTGTAGCAATTGCGGTAGCTCTGGGAATGATTATCTTTGGGGGATGGTGGTTTACAGCAGGCATGGGAGTCATAGTTTACCTAGGCCAACTCGAATATTTTCAACTAGCTAGTACTAAAGGTATTGTACCAGCAGCCAAAACTACTCTAGGGCTAAGTCAAGTCATGTTAGTAGTAGCAGCTCTCAATCCTAATTTAGTAGATGCCATATTTACATTAGCAGGAACTATAATCTGTTTTTATCTACTGTTTCAGCCAAAATTAGCAAGTATAGCTGACATAGCATCATCAATTTTAGGTCTATTTTATGGTGGATATCTACCTAGCTATTGGATTAGACTCAGAGTTGGATTTGAAGCTCAATTACAGATATCCCAAATAACTTTAGAAAACTACGAGTATACTTCATGGATAGACCCTTTGAGTTGGCCTTCGAGCTTAACATTTACTCTGCTTGGTTTTTGCTGTATATGGGCTGCTGATATAGGTGCTTATTTTGTCGGGAAGTTCTTTGGTCGAATTAGACTTTCAGAAATAAGCCCGAAAAAGACTGTGGAGGGTGCAGTATTTGGAGTTTTAGGTAGTGTAGGAGTAGCTACAATAGGTTCTTGGTACTTAGATTGGCCTGGTTCCCCTTGGACAGGTGCTGTCTTAGGGTTAATAGTAGGTATTGCTAGCCTACTTGGAGACTTAACGGAATCAATGATGAAACGAGATGCAGGTGTTAAAGATTCTGGACAACTCATACCTGGACATGGAGGAATTCTTGACCGCACTGACAGTTATGTTTTTACTGCACCCCTTATATATTATTTTTTCACCTTACTTTTACCAGCCCTCAAAAATTATAATTAGGGCTGGCTGAATGAATAAATATAGAATCCTGATGATACATCACTGTTAGTGATGGCTTATCTTGAGAAAAGGACCAAAAAATCACGAAATTAATATTTTTTCACTTAGGATTTTTCGTGACTTGAATAGGAAAAATGCAAAAAAATTAACATACTGCAACTATTGCCTATTCCCAACTCCCCATTTCCTGCCCTCACTAACAAATTTTTTGAGCAATTAACCTCTAATTGAAATATAAGATAAATCAACCTTTGACCAAACACAGTTGTTTTTCTTCTTTTGTGTTCTCAAATTATTTGCTTTTCCCTAAAATCTAGAATGAATTTTGTACCTTACTCCTAATAATAATTTTAATAGTTGAATTTAGGATTTAACTATTAAGCTACCTTGACAAATAAGTTGACCAGATTCTAATGTTAATTCTTGTAGTTTAACATCAGAACCTAAATCTACTTTGATGGTATTTGAAAGGTCATAATTAGACTTTTGTAAAACTTGAAATTCAAAATTTTCTAGCAATAATTTACAACTAGTAGCAAGCTTTAAACTAGTATGTAAATTTATTGGGATTTTTTCATCAAACTTAGACATAAAGTTAGCAAACAGACTAAGATGACCTGTAAATATTTCAGCTTTTTGGTCATACAATCGAATAGGTTTCTCTAGGCATTCTATAAAATCTGACTGTAATAGTGGGGTTAAAAAATCAACAATAGCCTGAGACAAAAGACCAGATTTTAGACTAGAATTAAAGTCAGATTGAAGACATTTAATCTGACAAAATATAGGAAAAGATTCTAAGATTTTCAATTTTTTTCCCCTGATAATTTGACCAATATTAATCCGAATACCAGTAGCAGATAATTTCACCTCAGTCAAATGTAATCCTCGAAAAATGACATTAGAAGCAGCAAGAGAAACTCGTGGGATTTGACCTGTAATAATTTGGCGATCACCTCCTTCAATATGAACCTTTAATTGTTCTACCTGTTCTAATTGTGATTTTAACCAAAATTGCAAAGCAGGAGATAGGAACCTACTAACAATTCTACTCTTTCTTTTTGTTGATATTTCATCTAAACTCTGATCAGCAATATCAGAACCAGAAATATGATGCAGTTGTGGTAAATTTTTATTCATTAAAGACACCATGAGGATTAGTATACTCTATACTCAATTGTGTAATTATTTCCAGAGATAAGAAATATATAAACTAGCAGATTTTAAATATTTAGGGTAGGAGAAAATATCCAATAAAGTGATGAAATAAATAATATGGATGAAAGATTACAAAAAATATTATCTCAGTGGGGCATAGCATCTCGGCGTCAAGCTGAACAAATGATCATAGCGGGACGAGTAAAGGTTAATGGTAAAATTGTCCAATTAGGAGAAAAGGCTCAACCAGACTTGGACAATATTGAAGTGGATGGTTTGCCCATTAGACCCGAAGCTCGACCATCACCCATATATTTATTGTTAAATAAACCTATGGGAGTAATTTCAACTTGTTCGGAACCTAGGAAACGTAGTAAAGTTTTAGATATCCTAAACGCAGAACTACGAAATGGAAAAGGTATTCATCCTGTAGGACGTTTAGATGCAGACTCTACAGGAGCATTACTCCTCACAAATGATGGTCGGGTGACTTATTGTTTAACCCACCCCAAATATTGTCTTTCTAAAACCTATCAAGTTTTGGTAGAAGGTCATCCCCAAGAATCAATCTTAAAGTTGTGGCGTCAAGGTATTATTTTATCTGGTAAAAAAACTTTACCCGCTGAGGTTAAAGTCTTAAAAGAATGTAATAGTTCTCAAACTCTTTTAGAAGTGGTCATCTCTGAAGGCAGAAATCGCCAGATTCGTAGAGTTGCAGATAAATTGGGACATCGTGTACTTAAACTACACCGTACTGCAATTGGTCAAATTAAGTTGCAGTTGCCTGGAGAGTCAGTTTTACCTATTGGCCATTATAGACAATTAAAGGATTTTGAAATTGAGTTTTTGGATGACCAAATTATTGAATCTAAATTCAGCTAAAAACTCTTTTTTATGACAAACAAGTATGTTTTTTAAAGTCTGAACTAAGTGGCTCAAATAATTTAAATATCTAAATAATATTTCTAAATTATTTTATACTTTGTGCTGGGTCAATTTTGCTCCCTCAATTAGCTATCAGCTTTTTGAACTTGGGCAACAACAAGCATCGGATGCTTAAGTAAGGCTTGAAATATACTTCATGCAAGTCAAAAAAATGACTATCCTGATTGCTGAATGTTGACTACTTGTTTAATAAAAATATATTTTGAAAAACAGAAATTTTATTCAATCGTATTATAGATATATTTAGGATTCTTCATAGCCAAAATTCTTTCTTAAACTAAGCATCCAAAATTAATCATATTATTGCTCAAATTAAGTTATACAAAATAAATCAAATAATGTTACAAGTAATAGAAGTGATTAAAATAATTTATATAAGATGTGATGTCTCTTTGATGAAAAATCAAGTTTATCCTTTCTCATCAAGAAACTAAAATAGATGCCCATAGAAAAATAATAGATAATAAATCTCTCAAATAAATGGTTAGATGCTGTGTCTTCTGAATTATAAATCCTGAATCATAACTCCTAGTAATTTGTAGCCAACTTTTTTCCAAATGGGATAACTATCCAAACTAAACAAGTTATAGTTTATATAAATTAAGTTAAAGCAATGGTGAATTTAACAGCAATCAAAAACCTAAAAAAAAGTTTCTCTTTTGTACCTTTAAGGCAACGTTTTAATCGAAGAAAAAAAATATCTTTTGAAGAAAAACAAAGTCAGGCATTAAAAGATATCGGGGATAAATTAAAAATGTTTAGAAATAAACATTCTATTTGTTTAAAAAGAGTGGCAGTAGTGACAATGATTAGAATTAATTTACTAGAAGCAATAGAAGAAGGTAATTTAAAAGAACTGCCAGAGCCAGTTTATATTCAAGGTATGATTAAGCGATATGCAGATGCTATAGGATTAGATGGAGAGGAACTAGCAAACTCATTTCCAACTGCAAAAGTTCAGGAAATTACGATAAAATCTCTGCCGAATTTATCAATGCTTCAGCTACGACCATATCATCTTTACTTTTTATATGTATTACTTGTTATTTTAGCAGTTCGTTTGTTACCTTATGTTAATAACTCTTATTATATATGGATACGAGATGGTATTACTAAGTCTGAAAAACAACAATATGAACGAGAAAATGAGGTTAATGTTTTACCTCCAGTTTCTCAGAAAAATAGGAAAACTGAGGGAAGATCTTCAGATCAAACAACACAAAAGTCAGATAAACAAAATGATGGACAACCTGTAGTTCTCAGTGTAATTGCGAAAGAAGAATCTTGGGTATCAATAAAGATAGATGGAAAAGTAGCGTTTGAAGGGACTTTAGCTCAAGGCACTCAGAAAACTTGGTCAGCCCAAAAGCAACTGGTTTTTTTCGCAGGCAATGCTGGAGGAATAATTATACCTATTGATAATGGGCAAAATATGCAACTGGGAAAACCGGGTGAAGTCAAAGAAGTTGTTCTTACTTCTACTAACACCCAAATACAATAAATAGTATAGCTTTAAGCTATCAGCTTAAGTTAAAGCTATCTATTGGTTGTAAAAGATTTTAATTTCATTAATGTCTCAATACTTTTTTGTAGTGCTATAAAAATTAGAGTTGTTGGAAAATAACTTAGGTTAGGGAAAAATGAAAACTTAAACCGAGCAATTTTGGTTAGTGACTTTAGCTATTTATGCTGCTATTAGGTACAAGTTCCATAGCCCAGTTGCTGTTAACATTAATTTGTCATCAAAATCATTCTTGTGATTACGGTAAATCTGATTTACAGTCGCGTAGTGTTTGACACCCACAAAGGCGTTTTCACATATCACCCGCTTATTGACTCAATTTCCGATTTTTAAGGCGTTGCTGTTGCTGTTAATTCTCCCCCTTTTTGTTTTTTATGGGGTATGCTGATATTTTTATACTAATGTTAATACCTTGAAACCCACTCATAACTTCAATTGGTATCTCCACAGGTATATTTCCTATCGACTTTTCCTGGTCTAGGAGTTTCAAGTCATGTAACTTTCCCTCTCTTGCCTTACTCAACAACAACACTTGCTTATTGTGCTCTACTGCTGCTAGATATTTGCGAGATAGACGCTTTTTTTTGCCTGAATAATTCAGTTTTTGTTTTTCTGAGTCCGTTCATCGTTGCAATGGCCATTCTGTGCCATCTATTACCACTCGTTCTACTCCAGGAAAACGTTCTATAAATCCTTGGACGCTGTTAATTTTGCGCTCTGGTAGTACCTTATTTCTTCATATACCGGAGTAAAGGCTGAGAGCAAGGATTGAAATGCTTTACGATTTAATCCTGTTAATGCTCTGAGTAACCTATCTTGTCTTAAAGCCTATTTAATGTTTAGCATTAAAGTTGGCCAATTTGCTGTTAACTTATTTTACCTTATTTCCCAACAACTCTATTAAAGATTATGTATGATTTCTCCTAATTGGAAAAAAACGGCCAGGGAGAATGATCAAGGCTTTTAGGTAAAAAAGTTATAACACATGGGGGATAACGGATTCTAGCTATTTTGATAGCATTAACGTAATTCCCTTGTCTAAACTTACTTTGACTGATTTTTTGGACTAGAAAATGTTTAAGTACCACTAATATTAATCCTCGTTATTTGTTGGGGTACGACCATAAATATCTGTCACCTCTTTGAGGCGATCACTTATATCTGAAGTTAACATCTCTGATCGATAACGCCAACTCCAATTACCATCAGGAACACCAGGCTGATTCATAATAGCTTCTTCCCCCAACCCTAAAATATCTTGTAGAGGAAAAATTGCCATATAAGCCACAGAAGACATAGCTAAACGAATTAAATCCCAATGAATGCCATGACCCCAACTATTACCAACAAAACGATAAACTCTTTCCTGTTCTTGAGGAGAACGCTTATTAAACCAGCCGACAGTAGTATTGTTATCGTGAGTGCCAGTATAAACAACCCAATTAGCAGAATTATAATTGCAGGGTAAATAGAGATTATCACTACCTGAGTCAAAAGCAAAATGTAGAATTTTCATACCAGGAAATTCAAACTGATCCCGTAATTGTTCTACTTCAGTAGTAATAACTCCTAAATCCTCAGCAATAACTGGCAGTTTACCTAACTTTTCTTTAATAGTTTTAAAAAAAGCCCTACCTGGAGCTGTAATCCATGTACCATTTTTAGCTGTAGTTTCACCTTGGGGTACTGCCCAATAAGAAACCAAACCTAGAAAATGGTCAATCCTAATCAAATCAACTATATCCAGCATAGACTGAATCCGTTGTACCCACCAAAAAAAATCTTCCTGTTCCAATTTATCCCACTGATAAACTGGATTACCCCATAGTTGACCAGTCTCACTAAAATAATCTGGGGGAACGCCAGCCATTAAAGATGGTTCACTTGTTTGTGAATCTAAAGAGAATATTTCTGGATGTGACCAAACATCAGCACTATCATGGGCAACATATATAGGAACATCGCCAAAGATTTTAATTCCTTGTTGATTAGCATAACTTTTCAGCTGATCCCATTGCTGAAAGAATAAATATTGAAGAAATTTATGGTACTGAATTTTATCAGCTAAACGTTGTTGCCATTCTGCTAATGCTTGTGGTTGACGATGAGCGATGTCTTGATCCCAGGTATGCCAACTTGCTCCTTCGTGAGCCTCTTTCAAAGCCATATAAAAAGCATAATCGTCTAACCAAAAAGCTTTACTGTTACTGAATTGATTGAATGTCTCTTTTTTTTCTTCAGAAGCATATTTTTGAAAGTTTTGGTAAGCAGTTTTCAGCAAAGAACTTTTTACTTGGGCAACTGAATCAAAATCTACCTTATCCCTTGGAAATTCTGGTATATTAGAAAAATCTTCCTCAGAAAGCCATCCTTCATCTTTTAACTTATCTGGACTAATTAACAGAGGATTTCCTGCCATTGCTGAATAAGCTTGATAGGGAGAATTGCCAAAGCCTGTTGGCCCTAATGGTAGAACTTGCCAAATTTTTTGTCCACTATTTTTCAAAAAATTCACAAAATTGTATGCTTCCTGGCCTAAGTCACCAATTCCAAAGGGACTGGGAAAAGAAGTTGGATGCAGTAAAATACCGCTAGATCTCGAAAGTAGCATGATTAAACCTAAAAAATACTAATTAAAAAAGTTATTGGCATTACACCTCAGTCTAGAATTAATTTTACGATGGGGAGAGTGTTTTTTTGATTGAGAGTTAAAATTTTGCTTAATTTTTTATCTTTTTTGTAGTCTAATTAGGGTTTGCTGAGTGTGACTCGTTGGACGAAAAAAGTCAATAAGTACTTGTAGCCCACATCTCTAATAATGACCATAGGTGATATAAAATAATAACTCGCAATTTTTTCGAGGTTAAATTCCTCTCATCTTGGTTAGGCAATGACTCTGTAAGTCAGGTAATTTGAGGTAGAGCTGATTACTGTCGTTGCATGACCTAAACATCAGCAAAGGCTTAAGTCCTTTAGCCTTTGCTGCAAGAGTTGTCACTCCAAATTGAGTAAATACCAATCCTATTACAACTGTCGTCACCCTAGTTAAGGGTAATTATCCAAGTATCTACAGCAAACCAAAACGGTATGGTTTGCTTGCCTCTCGGTACTTTACTATGGCTCAGGACACTGCTGGTAAAACGCCACAGTTAAGCAGTCCTAGCCTAAGACGCGAAAAAGATTATGGGAACCAAGTAAACCCTTGATTTCTCCTCTATTTGGAAGTAGGGAAAGCGTACACTAGAAAGATCAAGTATTAAGGATATCTTAACAAGCAACAGTATAACCTTATAGCTAGGATACCCAGACATAGGAGGCTACTGGAGACATTAGTTTTAGTTGAAACTACTGACAACGGCTAAAACTCAGCTATTAGCAAGGGTGGCATCTATAAGTTATTCCGAATAATAATGAGACACTTTTTTAGCTAAAACCCTTGAAAGCCAGGAAAATCTCGTCTCTATCTAAACTAGGATAGCTATAGTAGTATGAACGGCAAACCCTTAAACATATGTCCATTGTCAGGGGCCTTATGATGAGCGAAACTATGATGTACGGCACGTGAAGGAGAGGTGATGCGGCAAAATGTCCCAATGACCTCAAGGGGTGACAAGCACTTCAAGAGTATTACTAACAATGGTTTAAAGGGTTAAGGCATAGCAATCGAACAAAAGCTTAGGACACTCCCTCTATTCCGGATTTGCTGTATAAACTAAGATTGATGGCTTAGATGGCTTAACCTATACTTTGACTGCTATAATTCTTAAAAATTACGATCAATAGTAAAAATGATAATTATTATTGGTACTTAACAAAATATAGCTAGAAAACAGGCTCGGATATAGACATAAAGAGGATTTTACATCAAAAAAGTATAAATCCTAAATTATCAACGGTTCTAACTATTTTTAGGGTATCGACGTAATTCCCTTAGCTAGACTGACTTTGAGTCATTTTTTTTGAATAGAAAATTTTGAAGTCCCAATTGTTGACTTTTTTAAGTTAAGGCCACTAACAAAATTCAGATCAGCCAATTAAATTTTTTTTTGTCATTAAATCAACTGTGAGCTTTTGAAAGTACAAATACTTAATCTAATAATATAGGCATCGCTTTTAATCCCCTTTGATAATAGAGCTTTTTTCTCTGATGATAGATTTATCATACCAGGGACAATATTGACTAAGTCATCCCAAGTTATAACCCACAATTCACCATACATACCTACTCAAAAATTGCTATGTCTTCTATCTTTTCGACTAGCTTAAAAGAACCGACAAATGTATTTTTGATACCCGGATTTTTTGATGATAATACCAAAGTTGACTAGAAAATCGTATAAGCTAATACGGTTTAGTTAAGACTGAAAATCATGTAAATTAGATATTGTTTCCAAAAAAGGAAATGAGGTGTGGTGAATCTGAAAGACTTATCATTATTCTGTTATAATATACAAAATTTTGAAGTGTTAAAGGGAATTGGAATGGCAATTCTAGCCACGGCATTTTTAGAAGCTACATAACTGCCTCCACCATCCTCTGCAAACGCCAAAACTCAGGTAGTTCTAAACAAGTAAGGATGTATTATTGTAGTTCGAGAAATATCAGATAGCTAGAATATGATTCTCGATCTTTTTTAGAAAATGATCAAGTTTTTCTGACATTGCATGAGATATTCTCTGTCTAATGGTAGATTTCAATCTCTCAATATAGTTAATTAGACTACTTATTTTACTAACTGCTTTATGTCGTGTGTTGGGGAATATTTCTTCTTATGCTGACCAAAAGGTTCTTATGTTCACCAAAAGTCTGTATAAGTGAGTGAATACTGTCGATAGACACCAGGCAAAAAATTCCACAACCCCCTAGCTCCATCTATATTGCGATCGCCAATGTAAGCTCCAACAATTTCAAGACTTATGGAAGTACACTATATATAGGGTGCTTTCATATTAAATTATCCATAATATAATTAGTTTTTTTTTTGAGATAGATATCATTTTAAATAGATGTGATTTAGGAATAGCAAAATTGATTAAAAATTGTTAGATTAATTTTCTCAAAATTGTAAATAATTAGATAATAATTATATGATTATATTACCAGTAAAAATATGGATTTTCATTATGTTAAATGCTGTCAATATTTACTCAAATCTAACACGTATTATACAATAACGCTCCTTAGCAAACCCAGAGAGAAAATATTAGTCACGATAAAATCAACCGTTATTTAATAATAAAGTCTTTAAATTCAGAAGATGTATGGCAAAATGTCAAAGAAGAATTTGTTCTATATGCAGTGGGGAATTTAATTTTTGATGGTACAGTAATCAAGAAAAAGTATGGGTTAAAAATTAAACTTGTGCAACTATAATACAGTGTTAATGAATATAAAGTTATAGTTATTTTAAATAAGAATGAGACACTATTTGGCGCAACAATTACGAAAATTTTATCAAGATATTTATTGATAGGTGAATACATTCTAGATCTTTGTAATGCACTAAAATCATGTTTTATGTCATTTGAATCAGGAGAGTATTGTGGCAAAAATAGTAATTGATAACCCTCTGCTTCTACTAATTCTATAATAACCTTATAGTTAATCGACATTTTTTTTGAGGGCACCTCTAGCATGTTTTAGAAATTTAGCATATTTGCGATTAGCGTAATCCATAACCTCAGTTTAAACTTACCTGTCTTCCTCAAGCAATACCTGTAAAAAAGATATTTTTTAGTAATAATTGATATATAAGTTTTTTGGTATTTTGAAATATAAGTTTTTGTTGAGATTCTTCAACAAGCTGCTAAAAATCTTGTATTTATAATTCTGTTTACCGTTATAAATAAGACTATTATTAACAATTTTTATGCATGTATACTAAGGGCTATTCAGCATTTTTTTGGCAATTTAAAAGTTTTTCTGAATCTCATCCTTACATCTTTTTGATGGTACAGTAATCAAGAAAAAGTATGGGTTAAAAATTAAACTTGTGCAACTATAATACAGTAGTAATGAATATAAAGTTATAGTTATTTTAAATAAGAATGAGACACTGCACAACAATTACGAAAATTTTATCAAGATATTTATTGATAGGTGAATACATTCTATATCTTTTTAATGCACTAAAATCATGTTTTATGTCATTTAAATCAGGAGAGTATTGTGGCAAAAATAGTAATTGATAACCCTCTGCTTTTACTAATTCTATAATAACCTTATAGTTAATCGACATTTTTTTTGAGGGCACCTCTAGCATGTTTTAGAAATTTAGCATATTTGCGATTAGCGTAATTCATAACCTCAGTTGAAACTTACCTATCTTCCTCAAGCAATACCTGTAAAAAAGATATTTTTTAGTAATAATTGATATATAAGTTTTTTGGTATTTTGAAAGATAAGTTTTTGTTGATATTCTTCAACAAATTGGCTGCTAAAAATCTTGTATTTATAATCCTGTTTACCGTTATAAATAAGACTATTATTAACAATTTGTATGCATGTATACTAAGGGCTATTCAGCATTTTTTGGCAATTTAAAAGTTTTTCTGAATCTTATCCTTACATCTTATGGACTAACCTTTTTAGCACTCCCTAGATTTTGTAGGTTGGAAGAAGTTGCACATGACTTTAATTGTTCCTTTTGTAATTCTGAGAACAATTTCTGTGCTAACCACTTTTCAAAAACCAGCACGATTACAAGAAGCCTCAAAGATCAATGGGGAAAATAATTTTCCCTGACAGAAACTACTTATAATAGTTATCCTTAAAGTTCTTTTTCCTGACTTTAAATCATAATATATTTTGCAAAGTTTATTTTATCTATAACTATAATCTTTTCGCTTTGTCAATTGCTGGATTTTACCGACCCTTATTGCTCCCTTCCAACCTAGGAGATGGGGTTGTTTGTTCTAGCTTTTTTTTAGATTTTTATGTCATAAATTATTTTCTTTTCTCTTCATCTTTTTCTCTATCACGGTAATTTTTTTTATGGGGCAAAGCAATTTTTTTTAACGCTTTACCTATCACCAGAAGGTCGTTCTATCGCTAAATGATTCTGACCATTCAGATGTCATTTTTTTTAAGTTTGACTGCTATTAATATGGACAAATTCAAAGAAATTCTTATAAATCTAGTATTTTGGGATTATGTCTTTTTTAATAACTTGTTTTTGCTGCTAATATCGCTAGTTTCTTTTCGTCTATGTAAGCAAATATTGATGGTAGTGCGACTAATCTTAGATATATAAATTGCTTAGGTTTTACTCATTATATTATCAATAAAATTAATAATTTTTTGTCAATAGTCGTAGTTATAAACAACACTTTTACGACAAAATATAGTATATAAATATGGAAAAACTTGAGTAAGTATTTAGACTCAAGAAAAAAACACCTCAAACTGTAATTATAGACAGAAAGTGAAGATAAAAAAAAAGAATAGACAATGTTAGTAGAAGTGAGCAATATAGACCATCTAAGATTATTAGCAGGAATTATTGACGAGATTGGTATGGAGAATAAAATTAATCAACTACTAGGAGAAGAACTACCAGAAAAAATAATAGGGGGTCAAGCAGCCAAAGGAATGCTCTTAAATAGACTAGGTAAGGTTTTATTTATACTATATTTCTAATCGTCAATTTTTTTTCAGGGAAAAGCAATAGAAAATTTAATTGCTCAAGAAGTAAAAATAGAGTATTTTAATGATGATAAATTAGGTCTGGTATTAGAACAACTGTATCCCAGAGGATTAAATCATATTTTTATATCTATGGTGTTATAAACAGTGAAAATTTATGAGCTAAAAACAAGTACAATTCATTAAGAATCTACATGATTTTATGTTCATCTAGATTATCATAGAGATGAGGATAAATCCATAGAATATATAGAACCAAATACTATCAAAATTATTGATTTATATTCGAGAGATAAACAACAAGAATTAAAATAATTTATAATGTATTTAATTTGTATAAACTATGGAGATCTACTATTATAGATGATAGTTTGGTCTGGAAATTAATCTGAAAAAAAGTTCCAAGGCATCAAAGAATTTAATGGCCAGTTAAATTTTAACATTTTAATGATGGCAAATAGTGCAATAGAAGACTCAATAATATCTATATTTACTAACCAATATTAAATTTTTATCCGATTTAATATTTGTATAAAATAGCGATTAAAGTTACTCCACAAATAGATATTTATGATTTAAATTATATATCACATTAAGGGATATAGATATCAATAACTATCAAAAAATTACGGATAAATTCAACAGAAATGGTTGATAGTTAAAAGTCAACTATGTCGAGAATCATATTTTAAAAGCCTAGAGAAAAAAACAGAAATAACGAGCTAAACTTCACAAAAAACTGTTTACTTTAAGGTCATAAAAATTTGCTTGTATACGAGATCCATAAACAGTAAAAAGGAAACTTTTGATAAACTTTTTTACCACAAATTCACATAAATTAATATACAAAAAGTAGAGTCAAAATATGAATTATATTTTCCTTATAAATTATAAGTATAAGTGGGAGGAATAGGGTCAAAAATATAAATGTAAAAAAAGTGATTAGGTAGATTTATTTTGGTGACCAATGTTTTTGATAGGATGAAATTAACTACAGAATAAATGTGGTCAAAATATTAAGGAAAACAATTTATTTAGAGAGTTTTTATATTTATCAAATACTCCCTATTTTTAACTGATAGTGCAGTCCTTAAATCTCCCCATTTATCGAAATATTTAAGATTAATTATGGGCTTGGTTTATACTTGTGGTTAACGTCAACTGCTTAAAAACTTTAAACCGGACTAAATATACTTTCAAAAGTTAATTAGGTCGCCTTAATAATAGACATACTTTACGTTGGATATTTTAATGTTTTTAACCAATTAATTTATTGATTAATTATGAAGTTATAGAGTATATCTAACCTCACTTCATAGCGTCTATAATTACTAAAGTTTTTTCCTTCAAGTTTGAAAAAATACTATCTGCTCAATTGAGAAACTTGAGATGAAAACAGATAAAATGTTCAAATAATCAACAATTGAATAGTAGTGTAAAATGAAAGCACTTGAAAATTATTTGAGATGAAAGTATTCAAGTAATAGAAAGATTTTGGAAATTTCAACTGATATCATTCTATTGATTTACGATCCTCTCCTACCCCATATTATAAGTCTAAATACTTACTCAAGTTTTCTTTTCTTTTGATAATATATTTTGTAGTACAAAATGTAGGTAATAAGGAGCAGGCATAATCTTTCCGAGATTATTCTTTAAGCATTATTTCATAATCTTTGCTTTGAATACTATACTATTTTATCAAAGATATAATAGGAGCAAATTCAATAGTTTAAATGCTGAATTTGAGTCTTATTTATGTGGTAAAATAGTAAAGTATTATTATATTTTTTTTCTGCTAATGTTTTTGATATTTACTTATACATTAAAATCCCTAAAAAAATCATTTTCTACTGTTTAAATTTTAGACTTTGACTATTTGAAGTAAGTATATCTCAATCAATTAAATATTCTTTTCGAGAGTCAGAAGTAAGTAATTCTTCAAGTTCTAACAATAGTTTGTCACACATATTATCTAAAGGCAAATCATTAGGATCATAACCAAAAGGATTTTCTATTTCTAGTCCTATTGCTTCAATTCCTAATAGAGCAAAGCTAATTATTCCTACAACAAGAATAGTTATCCAAGATAATTTAGCTACCATTTGAAAGGGTAAAGCAAAGCAATACAAAAATAATAAATGTTTTAAGTGAATTGCATAAGCTAGAGGGATAGGTGTATTTAAAATTCTTTCGCAGGCAGTTTCATCTTTTACCATAGAGTCTAAGATTTGATTATAGGTAGAAAGCTGAATACTATCTATATAATTCAGATCGTATGCTTTACGGAAATAATCTCCAATCCATTTAGCTATTCTCATAGGAATATGATTAACTTCTTTCAGTTCTAAATATTGATTTTCGCTAATAATTGACCGAATTTTTAGGTCTAAACTTTCATTTCTTAAGTGTAATTTTGTACCTATTAAAAATCCTGCTAAAAGTCGAATTACTGCTATTTTTTCCTCTGTATCTTCTGGAGTTTTTTCAGGAATATTTACCCATATTTGCCTTGACAAAGATCGACAAGAAATTATAATTCCCCCAGTAGCTTTTCGCCCTTCCCAAAATCTGTCATAAGATGTATTAGTTCTAAAAACTAATAATAAACCCAATACTACACTAGGAATTAAACTAACTAAAATTGGTTGATGTATCGAAGTGAATCCAATTTTATAAAGGATCGTAATTATTGCAGAAAAAATCATTGCAACTGCTACTCGTTGCCAAACTTGAGGCACAATAGACCCTTTTAAGGTTAGCAGTAATTTGAGCCAGTTTTTATTTCTAATAATCATAGTTACTTTTTTAGTTTAAGGGAGTAAGGAACAGGAGTAATGTGACATTTTTTCAAGGCTAAAATTCTCATCATTGCTCTTTTAGGTTAAGGAAAATACCTGGCTATTTATAAAAATAGCTTAAACACAAAATAGATCGGTAAACAGGTTGTTTAAATGTCACACAATTACTATATTATGGTTTAATACTATTGTTAATATTTTTTGTCAAAGCAACGATAGAAAATAGGGAGATATATTAATTAGTTCTTTTCTACTCAATAATTATTTCATAAGCATTCAGACATTAGGTATTATCTATAAGTTATTAATTCATTATCATATCTAAGGAGGAATTAGTCTCCAAAGAGAATGAAAGTTGTGTATGAAATTGGTCACGACTCTAATCTTTAGTCATTCATTAAATATATTTAAAAAATGAAAGCTAAATGCTGATGTTATTTCTACTAGCAAAATGAACATATATAGAACTTAGCTATAAACACCATATATAGTAGGAGTCACCACAAATAGTATATCATTCATTTAAGTGAATAAGTCCTGATATGGTAAGTAATAATATAATTTTATTTCGATTTATAACTTACACTTTGGAGGACCTTGGCAGAAAGCAGAAGGCAGAAAGGAAAAAAAGATTTAAAGGGAGTAGAATTAATCAATATTTTTTCAGGAAAAAATAAAATTATTTAACTAGGTTCTAAACAACTATACATCTGATTATTTGATTCAGTTACTTGTTGAACTTGAGTAATATGTTTGTTAATCACTTCTTCTACCTCAATTTTTACATTATCAGACATTGAGGATAGCCATTCACTAATATTAATATGCATCCACTTTTTCATAGAATTATTGTAAACAACAAACTCAAGCAAACGACTCATATTTGTTTCGCCTGCTGTATCGCTAACTTCTTTCATCATAAAGTAGCTCAAGCCATAAAAAGGTTCAAAACCTTGTTGAAAATATTCTTCCCAACCACTCCAATTTAAGTTATTACGAGTTAACAATTTTTCTGCAAAAAGAGTAGCTAAACCCTCTGCATAGCAGTCAAGTAATTGTGCATTTAATAAATGAAATATTTCGTGAGCTAATTGACCATGGAAAGCATATTCAGATGGTTTACGATTTAAGTAAATAGTAAACTCTCCTTGATTTGCATTATCAAGTGAAGTTAAAGGAGTTGTATTTAAGTTTAAATTGACTTTTTTTACTGGTATTCTCGGTTTACCGTAAAGTTGTTGACTATAATTAAATCCCGATTCGACAAAAGAATAAATTTTAGGTTTATTAAAACTAGCATCTAAGGCGTTTATTTCGGGTGATAATATAAGTTGAGCCGAAACTTTTTGAAATGTTAAATTAGGAAAGTATAGAAAAATTATTAGGGAAATAGTTACGATTAATAAAAATTTTATTCTGGAAATAATTACCATAAATCTGTATCAAATAGGAAAATATGAGCTAATATTTGTTTGCTTTTGTTACCTCTAATTCAACAAACTTACTAAGTGTTATGTTGATAATTATAGTGCAATACGGTTCAGTTAAGGATTTTTTGGAGACTTCTGTAACCTTAAGAGCTACTCTAGCGGTTTCATACCACCACGAATTACCCAAAGACACTATTATAGTCCATGACAAATTTGGCTCCACTATGAGCTTATGCAATACCTTGCTCCGCCACAGAATTGCGATCGCTTAACTATTTTTATTCAAAAATACTTGAGTTATTCAAATTAAATAAACTTCATTTTTATTGAAGGATATTTTAATTCTGAGGACAAACTTATGAGTATTCTAATAAAATATTTCAGCATCTCTACTGATGAGCAAATAGCCTGGTGTCTTGCAATTGTTCGCGAGCTATAAAGATACCTCAGACTGTTTTTTCTCTCAATTCTGGTCATGTAGTTCTAGCTCACAATTTGATCGCCATTAGGAATATATAGGGAGTAGACCTTCAACCCATCGGTAAAGTAGAAGAAGCAATGTATAAGTCTCAATATCTGCCACAGAGGATCAATTGTCTTGGCACTTTAGTCTCCCACTACCCAAGCTCAGATACCTCGTACTGGACTTGAGTGTTGTCTGGTGTCCAGGTTTTCTTTTTTTTGAGCATACCAAAGTTTGCATTTCGTTAAGCTACAATACTTCAGGAATTTCTTCAAGGCTTAAGGCATCTGGTAAATGTTCTCTCAACAACTTTAGCTAGTAGTATGATCAATTCCTGTTAATCTTTCTATTCCTCGAAGGCCCATGCCAGATCGCGTACATTTTCAAATAGACTTGATGAGCATCATCACTATATCTTGGTTAAGTTTTAGAATGATTATAAATTGACAGCCACAATTGACACAAATGTTATGGATGCTTCCCACGTCTGTTAACATTAGCGAATATGTAGAAATTGGCACTCTGGACATTTCATACTTTTTCCCTTTTATTTTTTCTCAATTTATAATTCATGCAAGACCTAAAAACTAGCAGAAAGTTGTTGATTTTTGATTCTATAGTTTTGAATAATTATTCTTAGAAAAATAGGTGTTACTTTCGGAAAAGGATAAGTAGTTTCTTTCAAAACTTTTAATTCACTAGCTTTTTTTGCGAAATCATTCAATTGTAGTACTATTATGGCTAGTAAATCAATTGCCATTATAGAAAAAAAAGTCAGGAACTGTAGGTAGAATAAAAAAAATTCTAGTCATAAGTAAGTTCTGATTTATTGAACTTAAACTACGACTCATATCAATCAAAATATAGTTGACTTAAATTTTTTTTGCTGTGTCGTTAAATAGATAGTAAATTGAACTAGGAAGGTGTTGAAAAGCTGGAATTGAACTACTTAATTATTGAGCTATCTCCCAGATTCACCTCATATTCAGCTAATCCTACATGACCTGATAAGAGAAATAAACCATCTTATTGTTCATTTTTAATACATTCAATTCCCTCTACTAATTTATGCTGAGATTCAAATACAGGAGTTAAAGGAGATTGGATATTTTGGTATTTACGGTAAATTTATTTTAATTCTTATTTACGAGAAAACCCCAACACCATACCTATTAAATTGTATTGAGTATCTATATCTATCAAAATTATTTTTTTTCTCTTTGATTTGATGCTAAGACTCAACTTAAATTAAATGTTGTAGTCGTTTTACTAACACCACTTTTATGGTTAAAAAGTGCAATTTTTATGCAACTTATCTCATCGATTTCATCTGACTAACCTGGTATAATAAACTCTATTATTTTGACCAATAAACTAATAATAAAAACACCCAAAATACCCATAGCAATTACAAATAAAATTAAGCAACCTAAAAGGATAAAAATAAACCAATTATCAGCCTTTTTATGAACTGGAGAAGATGCTAAATGACTCTCCAATAGATCCATATTTTTAGAATTTGCCTTCCATGCAACATCAAACAGATCGCCAAAAATAGGTACAATACCAACTAGAGAGTCAAAAACTATATTAGTAACCATTTTTGTTAGAATATTTTTAGGTAATCCCATAGTTGAGGCAGAGAACACTATATAAATAGAAATTAGTCCTCCCAAAACATCACCACCACCAGGAATTAATCCTAACACTGGGTCAAGACCAATACCTAATGATGTACCAGGAACACCAATGGCATTATCCAGTAAGTCGCTAAGTTTTCGCAGTTGTCTAACCTTAGCTGCTTGGGGTTCATTACCTAGATTAGTAGGAGAAGGTTTTGCCATTATTAATTATTAGTTCTCATTTATTAGTCATCAGTCAAAAGTTAAAAGTTAAGAATAATCAATTAAGCTTCATAAAACTAATATAAAATGTCACAATTAGTTATAGATAATATGAAGTCTTATTAATTAGCCATAATAAAAATGTTTTTATAACATCAATTGCTTGCAATTCCCAATTTACTAAATTTTTTTTTGTAGGTATTCAAAGAAACATGATATGAGCTCACCTCACAATCAAAATTTTGTAGGGATTAACCATAGTTAATCCCTACTGTGGTCTACCCACATTAAAACTTTTATAATAATTATAGATTACTTTGTTTCAGTAAAATCAGCATCAATTACATCATCTCCACCTGTAGCATTTGAAGAAGAAGCACCAGAACCAGCATCACTATTTGGTGTAGAACCTTCACCAGGTGCACCACCAGATTGTTGATACATATTGCTGCTAACACTGTAGAGAGCTTGTTGTAACTCAGTAGTCAGAGAAGTAATCTTCTCATCGTCTTCTTGAGCGACAGCATCGCGCAAGTCTTTAATCAAGCCTTCAATTTTAGTCTTATCCGCTTCAGGAACCTTATCCCCCAACTCCTGAATTTGCTTCTCAGCCTGATATGCTAGAGAGTCAGCTTGGTTCTTACGGTCAATTTTATCACGGCGCTCTTTGTCTGCAGTAGCATTTGCTTCTGCTTCTTTAACCATCCGATCGACTTCTGTATCAGGAAGAGTCGAAGCACCTGTAATACTAATAGATTGTTCTTTTCCAGTACCTTTATCCTTCGCAGTTACATTCAGAATACCATTAGCATCAATATCAAAGGTAACTTCAATTTGAGGTACGCCACGAGGTGCTGCGGGGATACCATCTAAGCGGAAAGTTCCCAGACTCTTGTTATCGCTAGACATTTCTCGTTCGCCCTGCAGTACATGAATTTCTACATTTGTCTGACCATCTACAGCAGTTGAAAATACTTCTGATTTTTTAGTAGGAATAGTAGTGTTGCGCGGAATAATTTTGGTCATTACTCCACCAAGAGTTTCCACACCCAGAGATAGAGGAGTAACATCTAATAAGAGAATATCTTTAACTTCACCTGCTAACACACCAGCTTGAATAGCAGCTCCAACAGCTACAACTTCATCAGGGTTAACACTTTGATTTGGTTCTTTACCTAGGACTTTTTTGACTATTTCTTGAACTGCTGGAATTCGAGTGGAACCACCAACCAATACTACTTCATCGATGGCTTTTTTATCTAACTTCGCATCCCGAATGGCATTTTCTACAGGAATACGACAGCGATCAATGAGGTCGGAACATAGACCTTCAAATTCAGCTCTAGTAAGAGTTAGATCTAAATGCTTGGGCCCATCTTGAGTAGCAGTAATAAATGGTAAGTTAATTTCTGCCTGGGTAACACTAGAAAGTTCAATCTTAGCTTTTTCTGCTGCTTCTGTTAAACGTTGTAGTGCTTGTTTATCTTTACGCAGATCAATGCCTTCTACTTTGTTGAATTCTGCAGCGAGATAATCAACAATTTTCTTATCAAAGTCATCACCACCAAGGTGAGTATCACCAGAAGTAGCTAATACTTCAAAGACACCATCACCCACTTCTAGAATAGAAACGTCGAATGTACCACCACCAAGGTCAAATACTAAAATAGTTTCGTTACTTTTTTTATCTAAACCATAAGCTAGAGAAGCTGCTGTTGGTTCGTTGATAATTCGCAGTACTTCTACACCAGCAATTTTACCAGCATCCTTGGTTGCTTGTCTTTGGGAGTCATTGAAGTAAGCAGGTACGGTAATTACGGCTTGCGTTACTTGTTCACCAAGATATTTACTAGCATCATCTATTAGTTTACGAAGTACTTGGGCTGAAATTTCTTCAGAGGCAAATTGTTTTTTTAGTGCTTGGCAATCTAATTTAACGTTACCGTTAATGTTGAGAACTTTATAGGAAACTTCAGTGGTTTCATGGGTTACTTCATCAAATTTACGCCCGATAAACCGCTTTACCGAATAGAAAGTATTTTGGGTGTTCATCACCGCTTGACGCTTGGCAATTTGACCTACCAGTTGTTCTTCTTTTTTGCCATAAGCTACTACCGAAGGCGTTGTACGAAAACCTTCTGCATTAGCTATAACTGTAGGCTTACCACCTTCCATAACTGCAACACAAGAGTTTGTTGTGCCTAAATCAATTCCGACTACTTTTGCCATAACAGTGTTTTTGCTCCAATAATTACAAAACTTTTGTTTATTTGTCAACCGTTCCCAGAAATCTACAAAAATTTGATAAAATCTAGAAATTATCTAATTTTTGGCCTATTTCTATTCGGTGCTTGCTTCTGGTAACATCAGCGTTATCCAATTCACAAGTTACCACGGCCGAACTAACCGCCGTTGCTAGAGTATAACTAGCATTTAAGCTCTATAAAAACTGAAACCACAATGTTCATAATTCAACACTTTTTCTTTTCAGATATTAATATAGAAGCTATTTAATATTTTCAAAGTTAGAACAAGTGTTTCAACTAGGAAAACATTACTTTTGAGTCCTAGTAGTATAAAATAGATAATTAGTAATTATTACATCTTATACTAGTTACTAGCCCTACTTTTTCGGATTGACTTTAGGACTGATATTTCAGCTTAATCTAGGTTAAGTCTGAGGTAAGTCCATTTTAAATACAATCTTAAATCTTAAGATTAAGTTACTTATATCTATATTGCAGTTAGTTAGAGGATTCCATGAAGGTGTATTTACCGAACATCAGCAAACATTGAATTCTCAGGAACTTTAATTTTTTATAGTTTTACCTCTTTTATATTTCTAATTTAGAGCTAGAAAGCTACAATTGTCATTGTGGCAAACCGTAGTAAAATGTTGTGTTTGCCGTCTTTATTTTTTTCCTTACAGCAGTTTAGGAGTCTGGTGAGCTACAAAGTTTTATCACCTTAGTAAATACCGAATAGAAATTAGTTTTTAACTGTATCTCATCATCTGCGCCAAGTTCTTTAATCACTGGGTATGTATTAGATATCTTCAATAATACTGATTTTGGAACAGTTTATAATAATTTCAGAATCAATTCTTGAGATTTCATTTTTTTGATTTTTATTTCCGAAAATATTAATATCTAAAGTATTCTTTAAAATAAAAAAAACCATGTTTTACAGCAACATATTTTTTGAGTTTAAATACTTTTAATAATCCCTAATAATTCCTCTAAAAAATTATAAGATAATTTTACTTAAATGCTTATAGTTTTCCCTTAATAGCATAGTTTTAATGTGCATTTTGTAAGTTTTGTTAAGGTCAGAAACCTAACAAAAATAAGTATATGTTTGGTGTTGCTGTCACTATTTTAATGGTCGTGCTTTTAATTCCACACAGAATTTCATGTCGGCGACACTCAAAAACACAAACATCCTGTGGAGAAAAGCCTAACCTAAGGCAAACAGTTATGTATTAATACATCACATCACATAGGAAGTAAGATTTTCAAGGTGTGAAACTAAAACTCCTCTAGTGCATAAATCTTGTCTGCGTAGGAACTTGTAGGGACGTTCGATGAAAAGTCTTCACTATAGTCTACTAATTATAAATAAAGCAAGGCAATACTCAAGTCAAGCAGGAGGGAAGAGGAATTAGAGTTGTTTTGTGTGAGAAAATTAAAAAAGCTTAAAAGCTTACCCTATAGGTTTTTCAAAATCTCAATTTTTAAGAGCACGCTTAAACTGAACTTGTTTTGGGTTTTAGCCATTTTTTTTGGCTTAATTCCCAACAACTCTATTGATCCTAACGCCGAAGGTAATAGACTTCTGGTTTAGGAAGCAGGGGTTAATATCCCTCACAACAATTCCAGTTCAGTAGCCCCAGTTCAGGAAGTCCTGAACGGTAGCTTCTATCTCCTGCCTTTTCAAAATAGTTGTAAACCCTTAACAGAAAAGATAAATAATTCAGCTAAACTTTTGCTTTTGGCTTAAAATTACGCAATCTCAAAGCATTAGTAACTACGGAAACCGAACTAAATGCCATTGCTCCACCTGCAATAATGGGGTTCAATAACCAACCAGTTAAAGGATATAAAATACCGGCAGCAATAGGAATGCCTAAAGTATTATAAATGAAGGCAAAAAACAGATTTTGACGAATATTTTTTATAGTCGCACGACTCAGCTTAATTGCTGTAATAATGCCAGTTAAGTCTCCAGAAATTAATGTAATATCGCTAGAGGCGATCGCTACATCTGTACCTGTACCAATAGCTATTCCTACATCTGCTTGAGCTAATGCTGGAGCATCATTAATCCCATCTCCCACCATTGCTACAATTTGATGGTCATTCCTTCTTTTTTTCTTTTCTAATTGGAGATTTTTCACAGTTTCAGCTTTTTGGTCTGGGCGTACTTCAGCAAATATTTTACTAATACCAACTTCAGCACCAATAGCTTCTGCTGTTCGGCGATTATCTCCCGTTAGCATCACAACTTCTATTCCCATTTTTTGTAATGTTTGAACCACATTTTTTGAGGATGGTTTTAAAGTATCAGCTATGGCAAATATTCCCTCAATTTCACCATCAATTGCTATCCAGGCAGTAGTTTTTCTATCTGCTTCTAATTTATCTTGATAATTTAGGAAATTAGTAATCTCAATTCCTAACTCATTCATCCAGCGATCAGTACCAATTTGTACCAATCTATCAAATACTATTCCTTGAACACCCATACCAGAGATGGCCTCAAATCTTTCTGGTTCTGGTAGGGGAAATTTTATACCTTGACCTTTAGCATATTCGACAATTGCTGTAGCTAAAGGATGTTCAGATTTTCTCTCAACTGCTGCTGCTATTTTTAACAATTTTATTTCGTTTTCATTGGTAGTTCCTTGAGTAGTTATGTAGTCAGTAACTGTAGGTCTACCTTTAGTAAGAGTACCTGTTTTATCTAGGATAATTGTTTCAATTTTATGAGTAACTTCTAAACTATTTGCACCTTTAATTAATATCCCATTTTCTGCACCTTTTCCTGTTCCTACCATAACAGAAGTAGGGGTAGCTAATCCTAAAGCACAAGGACAAGCAATTATTAATACACTAACTGTTGTAATTAGTGACATTGTTAAATTGCCAGTCAAATTAATCCAAATAAGAAAAGTAGCGATCGCTACCCCCATCACTACAGGTACAAACCAGGAAATTACCATATCTGCTAATTTTTGAATTGGTGCTTTTGAAGCTTGTGCCTGTTGAACTAACTTAATTATTTGAGCTAATACTGTATCTTTTCCCACTCTGGCAGCCTCAAATTTAAAACTACCAGTTTGATTAATTGTTACTCCAATAACTTCATCTCCAGGTTTTTTTTCTACAGGCACACTTTCACCAGTTACCATCGATTCATCTACTGTAGAAAAACCTTCTTTTATTTTCCCATCAACTGGAATTTTTTCCCCAGGACGAACAACAATTAAATCGCCAATTTTGACTTTTTCAATCATAATATCTATTTCTTTTCCATCTCGAATAACTCTAGCAGTTTTTGCCTGCAAACCCATCAATTTTTGAATAGCTGCTGAGGTCTGTTTACGGGCGCGATGTTCGAGCAATTTACCTAATAGAATTAAAGTAATAATAGTAGCTGCTGCTTCATAATAAACATCAGGATTTAATCCTTGTCTAGTAAAAAAAATTGGGGAAAATGTGGGGAACAGAGAATACAAATAAGCCGCACCTGTACCTATAGCAACTAAAGTATTCATATCTACATAACGATTTTTTAATCCTTTAATAGCAGCAAAAAAAAATGATTTGCCACACCAAATCATAACTAGCGTTGTTAATATTAATTGTATTAAGGGATTGCCTAACCATGAAGGTATCCAAGACAAGTTTAATCCGGTCATCATTGGTAAAGAACCAATAATTAAAATTACACTAATAGTACCACCAAATATAACTTTATTGATCATTTTTCGTTCTATTTGGTGATTTTCTCTATCTTTGTCTAATAAATTTATTGTTTCCTGAAGTAGTTGTGCTTCAAAGCCAATATTTGTTACAGATTCTTGAATTTTATGTAAATTTGTTTTCTGGGAATTAAACTTAACTGTTGCTTGTCCTATTGCAAAGTTAACTTGGCATTCTGCTACACCAGTTACATTTTCAATTGCCTTTTGAATTTTATTAGCACAGCCAGCACAACTCATGCCTTTTAACTCTAGATATCTTATTTCCATAATTGCCTCCTGATGACGAGCGTGATAAATTTAGCTTCAAAGCTTTAAAATCAATTCTCTAGTTAACTCGAAAGAAATAATACTATTTACCAAAAACTTTTCTATGCTAGCTATTAAGTAGGACACCCACCCCTAAGCCCGACCGTGGACAGGGGAGTAGAGGATTAGAGAGTAGGGAACTGTCATACAATTTCTGTACAACATAAGAATAATTAACGCGCTACAGGCTCTTTATTATCAAAAAAATCATTTAGCTCATCTTCATTACTTAATAATTAAAATATAACTTATATTATAGCATTACTTTTGATGCTTAGCATGAGTAGTTAGGCATAAATAAATGTTTTTACAAAAAATATAAAAAAGAAGCTAGAAACAACTTCTCAAATACTTCTCACAATTTTGAATTCCTATTGCTATTTGAAGGATAATTACAATCATCTACTTATAAACTAACCAATTTCATAAAATATTCTTACAGTTATTGTACTTACGAGATTTACCCATAACTAATGTATATAACAGAGGTATTTTCTTACGGAATACTACGCCAACGTGTTGTGGAGCAAGCATGGTCTTTCCCTTTTACGTATGCTGTATGATTTGATATGTGTGCATAAGTCCTGAGTTATTATTTCCCATTGATCAGACAGCCAAAAAGAAAGAGGAAATATATATGATATCAAAGAGTACTTTACTATCCCTAAAAGTTATTTAATAAACCAATACAAGACTTAGATTAAAAATGTAGTTTTGCTTTCCAAGTCTTTTATTATTAGATCCGAATATGTTTGGATTGAGACTTTGGACATTTCATACTTTTTCTCTTTTATTTTTCTCTCCCTCTCTGTCATTCATCCTGCAAATATGCAACACCAAAATTTGAGATGTAACTACCTAAACACTAAGAATTTAGTATAATTTCATAAAATCATTGTTTTTTTCTAAGCTTGATAAATTACAACTTGTATTCTATATCTTTTATATAACGTTTATTAAGCTACTAAGGTACAATTATTTTTCTTCTTTTATATTCACTGTTTCCTGCATTCCTAATCTCTCAAATAATATCAAAATAACAATGAACAATCAAACAGCTATTTATTGTCATAATCTCAATAAAATTTATGCTAATGGAACTGTTGCCTTACAAAACATGAACTTAACAATTAACCAAGGAGAATTTTTGACTATTGTCGGACCTTCTGGATGTGGAAAAAGTACGGTATTGCGATTAATAGCAAAATTAAGTGATGTTACTTCAGGTAAAATTGAGTCAAATATAAATCAGAAGAAACATGAATTAGCTTTTGTGTTTCAAGAACCAGCATTAATGCCTTGGTCTCAGGTTATTGATAATGTGTATCTACCTCTTAAATTAGCGGGAAGATCTCTCAGAGAAGCCCGAACAATAGTGCAAGAAGCAATTAATTTAGTAGGTTTAGATGGTTTTGAGTGTTCTTATCCACGAGAGCTATCAGGTGGTATGAAAATGCGAGTTTCTATTGCTAGAGCATTAGTAACTCAGCCAAAAATTGTGTTGATGGATGAACCTTTTGGTGCTTTAGATGAAATGACTCGTAATAAGTTAAATAGTGATTTATTAGGGGTATGGAAAAAACGAAATTGGACTGTAGTTTTTGTTACTCATAATATTTATGAAGCGGTATATTTATCTCAACGAGTAATTGTTATGGCTGCTCGTCCTGGCAGGGTAGTAGCAGATGTCAAAATAGATGCCACTTATCCTCGTAGTGAAGACTTCCGAATGTCACAATTATGTAATGATTATTGTCGGAAAATTTCTAATTATTTAAAAATGGCAGTATCAAATTCTTAATACTAATTCTCAAAAAAAATACTATGCTTAGGTAAGACTTCAATTATTCAATAATTAATAGAGTTGTTGGGCATTAAGCCAAAAAAATGGCTAAAACCTAAAACAAGTTCAGGTTTAGAGTGCTTTTAAGGATTAAAATCATGAAAGCCTCATAGAGTAAACTTTTAAGCATGTTGAATCTTCCTACACCCAACAACTCTAATATACACCAATAAGCTTTTTGATAATTAATGCACCCCAAGTCATTTAATTATTCTAATATAGGAATTACCAAAAACTACTGTATCTATTAGATATCAGCGGTCGCCTTTGCTCCGAACATATTTGTGTAGCATTCTATAGGAAAAGTCTAAATATGAGACTAATATTTGCAAATGTGAAAGTGGTTATCATCGACCTTCCCTATCTATTTGCGCAGTTTTCCTTACGGAATGATGGCATATAAGGGCTAAAAACAATATTTTGAGGGAAGTTGCGATGACAAAAATTTGATGCTCAAGCAGTAGAATTATTTGTACAATGTGCAATGTTAAATCGAATGATTCAAATAGGTAAACCTCAGAGTTACATGGATTGAAATCTAGTTACTTCCAATGGGGGAGTGGTTTGCATTGCCGGAACCTAGTGGTAGCAAAAACGATCTTCCAAATGTAGCTCCACCAATAACAACGGTGGCGGCATTGATAGAAATGTTGGGGGGATTTTTTTTGTCGAAAAAAGGTGTTACATAGTGACAAATGATTAGGAGAGTTGAGGAATTTGCCGATATTTCAAATAATATATCAGCAAGCACATTGACTTGCATAATATATCAATTGACTTGGAGTAGCATAAAGTTTTATAATGTAACCTAGCTAAATAGTTTCAATGACAGCAGTTTTATCTTTCTATTCTGGTCATGGCTGTTTTACTAACATTGTGATCGCAATTCTCAATTAAGCAAGTATAAACTTTGTAGCTATCAGTAACATAAAGAAAACAAGCCCAAACTTGAATTATCTGCCACAATATTGTGAAGGTAACGGCGCAACCTACGCTGATAACAAACTTAAGAATTCCTGGCATTTGACTATTTACAACACTTGAGACCCGAATTTTGTTTTTTTTGAGCCGATAAAAGTTTGTAGTACATCAAGCGTGAGCATTTTCAACAATTGCTATTTTCTTTTCAGGAATTTGTCCTACAGCCAGTTATAACCAATTAAGCACTGTATTATGAAAAATATCAGTTACTCTCTCAATAGCTCGAAATCCCATGCTGTTAAGGGACATCTTGACACACAGCTCTTTAACATTATAACTATAGCCCTAAAGAGCTGGAATTTTCTTGGAATTGACGGCCACACTCACGGCATAAATAACTCTGCTTTTCCTAAAGATGACCATTTTTGACTACTTTATGACCTTAACAATAGGGATAATTCATATTAATGCTTCCAATATATCATTCTATATGATGCAAAATTTCAAAAACCAGCATTACCTATTTACTGGCAAGTTTTGAATTACAAAGGCTCTACTAATTTGACTTAACAGAAGGCACTGATAAAACGAGTTTTAAGGTTATTGAAAAAATATCAACTGGTTATTTCTTATTCGAGCAGGAGAGTCCCAAGGTGCAGATTTATCACAGTGGTTGAAAAATTTAACATCACCTCAAAAAGTTTATTTTATATTCAAGGATAATCACTATCGTCAACTTGGAATAAATTACTATAAACTGATAATTTTGGGGATAAATCTCGGAACAAAAATATTTTTAAGTAACATGAATTTTTCTAAAAAAATAGGTTTTTGTAAATTTAATATATCTACTTCCCAGGAGTTTTTGTTTGACATCCTCCCAGACTATGAAGGGCAAAGAAATTCTACCAAGGGTGAGCTCCCATGGGGATTAATTTTTTGCACTTAGCACGCGCTACCAACTCCACAGGCTATTTCATCAAACGGTTACCTCCGTGTCCGTCTTTTTGTCTCGGACTGCCTATACGCGATTGATTAATTAATAAAACAATATAACTAGAGAGTGGGAAGTTCTAGTAAGAACTATTGTGATCTTTGGCTTATAGCTATCTCAAGGTTAGAAACTTTTTTGAGAACACTATAAATGCTGTAAGCTAATTTATATAATACTTTTAGCCTTTAAAGCCAATAGTTTTTTAGGATAACTTTGTAAGATCGAGAATACAACAAAACAACTAAAAAGTAACTCGCTTATGGGCCCTATGGACGAGGCTTTAAAGCCAATTTTTTGTGTAAAATAGAAATAATCAAAAATTTAAAACCATAAAAATGACATCAGAAAAAGAATCCTCAAATCAACCAATTATAGATAATTCGACAACTCCCTGGTGGTTAAAAATATGGCAGGAACAAAAAGAAAATATTAAAGTTGTAGCGATCGCTCTATTCTTATCTTTATTAATCAGAATATTCATTGCGGAACCGAGATATATACCATCAGATTCAATGATGCCTACCTTAAAAGTAGGCGATCGCCTAGTAATAGAAAAAATATCTTACAATTTTTATCCACCCACAACAGGTGATATCATCGTCTTTGAAGCACCCCAACAATTGCAACCCTACGGTTATACAAAAAATCAAGCTTTTATCAAACGAATTATAGGTTTGCCAGGAGATACTATTAGAATTGAAAATGGTACAGTATATGTTAATGACCAACCCCTTACTGAAAATTATATTGCGGAACCTCCTGAATATGCTTTACCAACTTCAATTAAAATTCCTGAAGATAAATATTTTGTAATGGGGGATAATCGCAACAACAGTAATGACTCTCATGTTTGGGGTTTTTTGCCTAGAAAAAATATTATAGGTAAGGCAGTATTTCGTTTTTGGCCTTATCAAAGATTAGGATCAGTTTAAAATAATCAGAAGGAATTAATTTCTGCTAAAAGTATTAATGAATAATCAGTTTAATATCCCAGCTCTGAAGTTTAAAATTGCAGAATATTCCGATAATTTCAGATACAAATATTAATCTTAAAACCTCTAAACTTCATCCGTATTGCTCACTAGTAGTTTACCTAACTAAGATAAAATTATCTATTAATCTGTGTGTAAAGTTATCGAAAAACCTTATTCCTAAACATTCCCATACTGATAACTTATAACATAAATAACAACTTACCATGGTTGTTGATCTAAAACAGGAGGTAGACTTAAATTAGGAAATTTGTAGAATGTATCTCCTTGTTCATCTATTTCTAGAATTGCCGAGAATATTTGTACTTGATTTTCTAGATATCTCTGAGCAACTTGAGCATCAACTTTAGCAGCAGCAGCTAATTGAATTAGAGAGACTTTACCATTTTGAAGCTGTAATAATTTATAGAAAGCATCATCTAAAATACGCTGCTGCTGTCTATTATTTAACATATTAACTATAAATGCACCTAATACAATTCCTAACCCAGTAAGTATTACAATTTCTATAATAGCCATTTTATCTAAAAAGGAAGAAGTAAGAATCAAGAAAAAGTAAGAAGTAAAAATTAACTACAAAACCTCCTTTTTCTATAAACAACAACTAGGAATAAAAATCAGGAAAACTCATATATATAATTCTAGTATAATGACACTAATTAACTTAATTATTTCCAACTTTTTTCCTATTTTGTAGTCTAACAAATATAACTTAAATTAATATTGTTTAATTTAACTAGAGTAATTGGTAATTTAGTCTTGTAATTATCTATAGCATTTTCCAATGATATTTCAAAAAATAGTTACTTATTTACTAACAGTAAAAAGTCCGCTGTTACCTTCTTAACCGTTGACTTTTGCATGTATATCGTTTTCATAAAAGAAGTCAGTTTTTTTGACATAACTTCTAGAAATTTATATAGAAATTGATAGGCTAAATCATCCAATTACCCTAATTTAATACCAAATTTCCCAACCCAGAAATTAGGCTTCAGGTTCCACAATATTTTCAAACCCAGCTACTACCTTCGCAGAAATAATTTTGTCTCCCTTGTTTAATTCTTCCAAAACCTTTTTTCCTGCAACAACATAACCAAAAACCGTATAACGACCATCCAATAAATTTACTCCGGCAGGGGTTAATTCTGGTTGGAATAGGAAAAAGAAAAATTGAGAAGAAGCACCATCATTTTCAGCTTCAGGCCGAGCCATTGCTACTGCACCATAAGCAGAAAAAGGCAGAACAGGAAGTTCGCGAAAACGGCCAATCTCTTCTAAAGTAAAACTATATATCGGTTCGTTGTCTCCCTGGACTAAAATTTCTAATGGGATATTACGGTACTTCCCACTATCTGGGTCAATAAAACCAACTTCTGGGCCTGGAGGATCTCCAGCTTGCAAGACATAAGACTGTTCTGATCGAATAAACTCTAGGCCATCATAAAAACCCCTCTGAACCAAATCTACAAAATTACCTGCTGTAACAGGGGCACTATAACCATCAACAACTAAAGTCAAGGAACCTTTATTAGTTTCCATGTCAATAGTAGCGCGACCTTTGAGTTGCGGTAAATTAGAAAAATCTGAAGGCACTTCAAACGGAAAACCTACTACCATTAACTGTTCAAGCTGACCTACTAATGTCAGTAGTTTTGCCCGTTGCTCTAATACCTGTTCCCCATCTTTAGCTTCAGCAACCTCTTTAATATCAATAATACCTTGATCGAGTATAGCAATTATTTCCTCTGCCTCAGGTTGTTTTGATTCAGGAACACTAGCTAGCAATTTAGGTTTATTGATACTGAGAACTCTTGATGCAGTCCCAATATCACTAACAACAGAAGTCCAACGTTTACCTCGTAATCTGTTAGAAATATCTTCTAGACTACTTTGTATTTTACGCACAGGTTCATTTTCTATTGGTAGAGCATACCTTAACAAGGCCCTACCATCAGTAATAGGGTCTCCCTGGGGCAAACGACTTTGACGAGTTGTTGTCATACCACCGTTCCACCAAGCAGCACTAATACCAATAGACAGAGTAATAAGTAACAGCCCTAGGATAGCAGTTTTAAGCAGACGTTTACAAGTGTTCATTACGAAATTGCGCAAATTTACCATATTTGTGAAATTTTATTCTCTTAGCTTATATTACATGTCTGTCCACAGTCTTAACGAAGTCATAAGTCAGTATTCAGAAGTCAGAAGTTATCTTTCTCTGCAGTATGGCAGTGAGCAACTCTCCAAAGATATTTCGATAATTCAGCTGGGGTCCCGGGACTAAATTATTTGGGACAGATTTTTGGGGACAAAAATTAGGTGATTTTTGATTAGGCGTTAAAGGTGTTAAAGGTTATTTTTTATCTTCCACAATATTTAACCATTACCTAAAAAGGTGACAAAGAGAACTAAAATTCTAATTGGACAATGCGTTGCGCCCTCTTACCTTTTCAATAATTGAGTCGATGTTACGGACAATTGGCCATCAGTTGCTCGCCTTCTTTTGCCAAAACTTCTAGAGAAATTTTGCCAAGTTTGCCCTCTATATTCCGATATAAAAATGGCTATGGTGTGGATATTTGTTCCTTTTTATGCATAATTTTTATTCTAAAAAGACAAATTTTGGTACCATTAATAATAGATTCAGTTTCAGCAAAAGTACTTAATAATTTTAAATACATTAAGCATTTACCTATAACTTGAGATCCTTACAGATTATAGACTCTATTTTGCAAATTAAAGAAAATTTTCTTAACGTATATTCGTTGTTTATCAGTAATTAAAAATTTTATAATTTGAAAATATTTGTGAGTATAAACTAAGCTGATTATGGATAACAATGTAAATATTTTTTTCTGGTATTTTGTAGATACATTAAAAAAACATAAATTTTAGTGTTTTATTTTTTATTTTATCTTGATTTAATTTCTAATTATTCGATAGTAATATTGAGGAATTTATCAAAATAAATGATAATTTTTTTTCTATAAAAAAACTAAGATAGGTCTTTTATTAGTCTTTTAAACATTAATTTGGCTTCATGATATCAAATTTACATCTCATAAAGCTACTTTTTTTATAACTAGCACATAGAGTTAAATCTATAAATCATAATTATTCTATATCAGGAAAATAAATATTATTTTTTTTTGATATTTTTGATGTAAAAATACAAAATAAAATGCTTATAAGTTAGGTCAAGTAATAACATTTTAAAGACAGACTATTTAGTCAGATAAATAGATAAATATAGTCTTGAACTTTTTAAAATATTTATTAAAATTACTCATTTAAGAGGAGAAAATAAAAAAATAAAATTTCATTTTATACAAATAAAAAAATGTTGCATAGCCCGACTAAAACTTTCAAATAGAGTGTATTTTTGGTATTTGATTGGGTAAGGTTTCCAATCCTTTACATCTATGTTCTATATTCAATATTCAGAGCAATTAAAATAAAATTTTTCAGATGACCCCCCAGATGAAATTTTCGTGAGCCCACGAGATATTTATAGTCAAGTTGAGGTAATTTGTTCATTATCATTAAGATGAGGCTTGTTGATTTTGAGGAGACTTATCTTAATAATAATAATTTTGCTGAATACTTTATACATATAACTTTTCAACCTTGATTGTCACTTCTTGAGAACTATTACTTCGAGTCCCAAATTTTTACTCCTAAGTGATAAACTCCTGAAAATATTTATAGAGAGTATTGTAGGATGTCTAATGTTAACTTCTAATTGAAACAATTAAAAACCGCAATCACGGTGTTATATGATTTCTAGTAATGATTTTCGCCCCGGTGTGACCATAGAATTAGATGGTTCAGTTTGGCGAGTAGTAGAATTTTTACACGTTAAACCAGGCAAAGGTTCTGCTTTTGTTAGAACAAAGCTCAAAAATGTACAAAATGGTAATGTTGTGGAACGAACTTTTAGAGCTGGAGAAACAGTCCCTCAAGCTACTTTGGACAAGAGAGCGATGCAGCATACATATAAAGATAGTGACCAATTTGTATTTATGGATATGGAAACCTATGAAGAGACCAATTTAAGTTCTGAACAAATTGGTGAGCGTGTTAAGTATCTGAATGAAGGGATGGAGGTCAATGTTATTATGTGGGGTGAACAAGTAATAGAGGTGGAGCTACCCAATTCTGTAGTATTAGAAGTAATCGAAACTGACCCTGGGGTTAAAGGAGATACTGCTACTGGTGGTAGTAAACCTGCTACAGTAGAAACAGGTGCCCAAATTATGGTTCCCTTGTTTATATCCAAAGGAGAACGGATTAAAATAGATACCCGTAATGACTCTTACTTGGGTAGAGAGTAATTCTAGGGTACTTATTTTGGCAGGGTTATTATTCCCCTGCCTTTTGGTGTTAAATTCTATATTTATAGCAGCATTCTACTTTAAGAAGTAAATATACTGATGGTTTTAGGGAGTAGGATATTGACAACAGTTAGGTTTTTTTATTTGGAAAGGCATCATAGGGTAGAACAAGTTCGACAAAGGGGAAAAGTTGACAAGAAACCACAAATGATGGAAATTTCTAATGATCAACTGTAAAAGTTCTCGCTTCAAAAAAGATTATGAAAATTTTTGAGCTATTACACACAGTGTCCCATTCCAGAGAGATAATCTTTGACAGACTAAGTTAGTTACTTAGTATAAGATTTTTCTCGAGTTACAATAAATAAGCCCTGCCCTGATGAGAAAGTAGGATAGGGAACAAGCTCAGAATATCTACCAATCAGTTGTACTATATTAATCTGGAATCTGCTGTATATATTTGATAAGTGAGAGTTTTTCTGACTTGAGAATTTACTTAAAGATACTTAAACATTAATAAAATTAATATTTTTATTCAAAATTAATTTAGTTTAATGCTAATTAACTGGAGATATAAGAACTGTGCAATTAGATTTACATCAACTTCAGGAACTACTCAAAGCAATAGACCAAACTAATATTTCGGAGTTGACTCTAAAAAGTGGAGATTTAGAACTGGTGGTACGCAAAGAAACTTCATCTAGCGATCGCCACTCATTACCTTCTTCTAACAAGAGCGATACTATTTCCGAATTAGTTTCTCCTACTGTAGCAGCGTTGGAAACAATGGCTACGTCAAAAACCTCTGTAATGCCTCCTGCCGCACCACCTACGGCTTCAAACAAATTTGAAGAAATTTTGTCTCCAGTTGTTGGTACTTTTTACCGTGCTCCGAATCCTGATGAAACACCGTTTGTGGAAGTGGGCGATCAGATTACTTCTGGCCAAACAGTTTGTATTATTGAAGCGATGAAGGTAATGAATGAGATTGAAGCAGAGGTATCTGGACAAATAATGAAAGTTTTAATTAAGAATGGAGAACCAGTAGAATATAATCAACCTTTAATGCTAGTTAACCCCAACTAAACTTGATCAAAATCATGCCACAATTAATCCATAATCCTATTCGGATTCAATCTAATGGTAATAAACTAAGCAAATTGATAAGTATATTGGCTGTGTAAATAGTCAAACCCATTCTATTAGTGTTGCCCAAATGCTTTCTCTCAGTGGTTGGATGGAACCAGGTTAAAGGCCAGAGTTTGATGAATTTACCCTGGTACTCAAGAGCACTCTCTTTGTTGAATATCAAGGTGGACAATTGTAAGTTGATGCAGGCCAAGCATTAATAGCTCATAAAGGAGAATGGGTAAAATATAGTACACCTGGTGCAGAGGGAAAAGAATATGTCGCTATTTGTTTATCTGCTTTGTCCCCGGATACTGTAAATTGAAATTTTGAGTAAATGACAATTATAGCAATTGTGGCCATAAAGTCAAAAAATTTCTATCAACAGGACTCATTAGTTGTTAGTCATAAATTTGTCGGGAGACAAGTGTCGCAATTAATATTTTTAGCTGTAGATTATAAAGAGTAAGTATAGAGTGAAATAGAAACATTGTAGGGAGAAGAGAAATTTCCAAGGTATTTTCCTGGCTTCTGTATTTGCTGTCTGGAATCCTTAGAAAGATAAAAACCTGTGCTGGAGATAGAAAATTTAATTCAGCAAGGAAGGAATAAGGATTTTATTCTCTACACAATTTGAATTGCCTAAACTCTGTATACTCTTGATTCTTTACTAAAAGTTATGGACCCTATTGATGGTGCTATCTACGATAGTGAGGTTAAGTTAAATAGGGCTTGCTAAATAAATATAGAATCCTGATGTATCATCAGTTTAAGTGGTATTAGACGAGGAAGAGAGTAAAAATACTCTTGTTAACATTCACTTCTTAGGATTTTCCCTTAACTAAGAAGGAAGAAATAGGGAAAAATCAACACTTACAACTGTTTCTTGACTGTTTCTTAATGCTTATTCCCTATTCTTTTCTTTAACTAACAGATTTTTTCAACAGGCCTAAAATACTAATATCTATTTCCCTATTTACTAAGGGGATAAATTTTTGTTTCGTCCTGTAGATGTATTGAGATGTATAAGTTAGACCGTTTCACTATCAGGACTCTAACTGCAAAAATCACTACTTGTTGTACACCACTACTAATACTAAATTTAGTTGTGCATTACGGCCCTTTATGTCAATATTGGCTAAGCTTTGCGAAATGTCAAACAATAATTATAATATAAACAATTTAATTATGTAATATATCTTGATAAGAGACTGTGTTTATTTGACAGTGATCATTGCTTTTTTATTTTCTTACCTTCAATACTTCTTCATGGCTATCTTTAGCTTTTTGTACAAACAGTCTCTAATTCTATCATTACTTTAATATCCAATCCCTTCATATCCCTTTCTCCAAAAGCTATACAATAATTATTCAACTGGAATTAATATTACATATCATAAATCACCAGATTTTCTTCTAGAATTATGTCAATAGAGGTGGATTTTAATTTTCTTTGACTTGCTGATTAATTATCAAAGTATTGGTAGGTAAGATCAAAGCTCTACCTCAAAAAGTTAGAATTTTGGGCTGATCATTGCAGAAAAACAAGAGGCAATTCTTACAACTACCTTCTCTACAATTGACATTTTTCGTAAGTCCTAACTTGCTACTCTCTCCCTAAAAAGACTTTTTCAGCAAACCCTATTTATTTGTTTGAAAATGACCCCTAAAGTTTTTTTTGATTAGGACTTACGCAAATAAACCCGACTTATAGAAGCAATATCATTTGAAAAATAGGCATTGACAAAGAAGCTGGTTTCTGATTTTTTTGTGCATAAATTATAAATTATATAGGCCTATGTAAACATCTTAGGACATTCATCCGTTTTCTATTCTCTATTTCCTGTTACCTTATAAGCTAAATTTATTGTCTTCACCAAAAGATGTAGTAATATATCTAAAATTGAAACTCTTGTTGAAAGTTCTGCCGAGTAATAGGTTGAGATACTTCTAATCCTTCACTCCCTAACATTTCTAAAGGTTTGCCCTCCACAAAAATCCAAACTTTAACATCTGGCTCTAAACTAGAGGCAGTATAAATAACTTGTCCCAAACGCCCTATCATTGAAGCACTACCACCTCCATAAGTAAATTCCTCAGATAAGTCAATGTAAACACCGTTGTTTTCAACAGTTAAGGCTTGAACTTTGGTTCCTTCGGGTATTGCACTTACAACATAGGTATTTTCTGGGCGAGATAATAAAAGGTCAAAAGCAGCTCTTAAAATAGCTTCCGGTTCATCTATTTCTTTAATTTTTACCGGAGAAGACGCTAAGCTAATACCTGTAGCAGTATCCTTAACCCAGTAGACTTCCACAGTCTTTTCTGTAACTGCTAATGGTTCTGATTTTATAGACAAAGGAAACTTTTGGGAGTTTGGAGATTTAATTGTATCAGAAGGAACAGAAGGTAAAGTCTGTAATGGTGACTCTTGAGTAGGGAGGTCTGTAAGAGTCTGGGGATTATTAGAAGTTTTTTTGGTGGTCAATTGTAAATTTGTCCACAACGCAATACCACCACCCACCACCACTGCTAATGCACAGACACTGGCCACAATACTAACAGATAAATTTAGAGTTTGATTTTGTTTTTTCATTTTGACGATCCTTGAGGATTAACATAATGGCAGTGAGGAGCTGAGTTTTCAGTTTCTCTTAGGTTAACTATATTAACTATATTAAAGCTGATTTATAAATAGAATCTCAATAAAGTTGGATCAAGATGAAATTATTTGTTACATCGTAATAGATTAACTTACAATAGCCCTCAATAATTTCGAGAATGTTTAAAGAAAATTAATTAAAATTTAGAAGAAGAAAAATGCTTGGTAAATTGTGATTAATTTTATACCTATGCGCAAAAAAAAATCCTGTAAGAACATAAAGCATATTCCAAGTATATGAAGTACAGATATTAATCATTAAATGTTTCTAGTATGGGCATCTTGCAAACTCTTTAATGGTTGTGGTGCATCATTTTTTTGACCATATTAGGGATATTGAATACAAGGTCTTTACAGTAGCAAAATTTTTAATTCCTCAATCTATATTTGTATAGATATGATAGAAGTATTAATTACAAGTTTAAGCCGAAAAATATCTCCATTGAGAATTTAGATGTAGATGACTAGAGGTATTGTAATTGGATGAATAAAATTCCCAAAGGTTGGGTTTATATTCCTGGTCTTTTTCGTCTTATTAGAGAAAGTTGGCAAACGGGTAGAAAAGTCTATGAGAATAAATTTTTCGTCAATAATGACCATGGTTATATCTTGATTCATCTGTGTTTAATCAAGTACATCCTCCTTGATTACATCGTAAATTTTGGGGATTTATGCACAGTGTTATTTATCAACTCCAAAGTTTATAATTTGGTCACTTTATTGTGCATATTTTATGTTTAATTTTGAATAGTTCTTATTTTTTGTTACCTGATTATTATAATAAAATACCTACTTTTTATGATACTTGGATATCAACAATTCTTTTCTTTCATATTCTTGAAAATTTAAATGGGAGACCTAATTCTTTAGAAAGGTTAGCATTCTAAATACGCCTAACAAAAACAGATAAATTTTCGGTGGTTTGGTAAATGTGTAATGCTTCTTTTCTAGAAATTAGCACAATCTTAGATTTCAAGTAGTACAGTGGTAAATAAATGGAATAATTAAGTATGTTTAAAGAAGGATTAGACTAGATTTTTGATTGAGTTTTACAATAGTTTTATTCTCTTCTATATTCCGTGCTTTAAAAAGTAGTATAAAAAATGTTTCAGCTATTAGTTGATCAGGAAATATAAAAGGCTTCAGATATCAGACTATAGGGTGAGTAATATTAGCTGAATAAAAGTGATTATTCTCCCCAATGCTTCTTAAAAACTTACTCCTGTAATACCGTTTTACGAAAGTCATACATTCATTCATTTAAAACTCATGCATGAATATTTTATATTATAGGATCTATTCTTTAAAACTGTAGTAGCTTCAATAAATTATTCTACTTCCATTGTTTGAAACTAAGTAGGTTGGTGTTGAAATTTGTCGCTATGTAACAAAATGTAAATTAACCTCAAATCAACTGTGTGAAGGATCTTAGATTCAGTACACAAATATTAATATAGCTAAGTTTTTTCACGCCACCTACTTAGTTTGCTTGGTATGCTGGGGGTCAGGGGAGGGTTAACTTCATTTCTGCCGCGTAGCGCTTAAGCCCAAATATATTCTAATAAGGTTTAGATAAAACTAAAACTCATGAATTAAGAATTAATTAGAGTAGCCGTTTAGATTACAGAATTACCAAAAAATCCTTAACTGAACTTATTGGATTATAGTTCAATTTGACTGATTAAGTGGTGTAAGTCCTATTAGTAAAAACACAGCAATAATTAATAAGGGAAAAATTATATTTGAATTTTTCAAGGGTGAATAAATTATTTTAATGCTTTCTCAATTAAGTCTTTTAAGGTAGATAATACTTGCGCGACAACAATTTCCTGGCATTGGTGAGTAGATCTTTCTATAAGTTCAACCTTGCCAGATTTTAATGATCGCCCAGTAACTATTCGATAGGGAATACCAATTAAATCTGCATCTTTAAATTTAACACCTGCACGTTCATCTCGGTCATCTAAAATAGTGTCTATTCCTGCTTCATTTAATTCCTTATAAAGATTTCCTGCTACTTCTATTTGTTGAGTATCTTTAATATTAGGAATACAAATAACTACATGATAGGGAGCAATAGCCACAGGCCAAATTATACCATCTTTGTCATAAGACTGTTCTACTGCCGCTTGGGCTAAACGAGACACTCCCACACCATAACATCCCATTAACAATGGTACTTCCTGGCCCTGTTCATTTGTATAGGTTGCTCCCATAGCTTCAGAATATTTTGTCCCCAACTGAAATATATGACCCACCTCAATGCCTCTAGCAGTTTCTAGAGTTTTACTAGGGTCATGTACAGCGCGATCGCCTTTTTTAGCCTTTCGCACATCTACCACCAACTTTGGCAAAGCAAATTCTTGACCCCAATTTGCCCCCACAATATGATTACCTAGTTCATTACTACCAGTTGCAAAATTTGTCAAGTATACTGCTGTTTTATCGACCATTCGTAGGAACTTAGGACTAACCTGTTTACTAGAAGTGATATAATCATCAGATAAATCTGGAGCAATATAACCCAAAGGTAAAGACTTAGCTGCCCATTTCTTTTGAGCTTCCACATCCGGTACACTCAAAGCCAAAACAGTTTTGGCCTCATAATTTCCAGCTAACCTAGTCAACTCATTCAACAACTTCACATCATTAACATCTTGGTCTCCCCGAATACTCACCAATACTAAAACACTAATCCCATTATCATAAACGGCTTGGTACAAAACATTTTTGACTATATTAGTTGCAGAACAATGGAGAAACTCACACATCTTTTCAATAGTTTCTGTACCAGGAGTTTCCAATTTGTCATAAGTATCAAAAGGTGAAGCTTCTACATCTACAGGCAACGAGATAGCCTTTTCCATATTTGCCGCATACTTACCATCTTGGGTATAGAGAATTTCATCCTCGCCAGCATCGGCCAAAACCATAAATTCTTGGGAAGCAGAACCACCTATGGCCCCAGAATCAGCATCAACGGCCCGAAACTGTAACCCACTGCGACGTAACATATTTCGATAAGCCTTATCCATATCCTGATAAGTTTTTTTCAGACTTTCCTCATCAGCATGAAAGGAATAGCCATCTTTCATAATAAATTCTCGACCTCGCATTAACCCAAATCTAGGACGAATTTCATCTCGGAATTTAGTTTGAAGTTGATAGAGATGTATGGGTAGTTGCCTATAGGAACGAATAATATCTTTAGCAATAGTAGTTATTACCTCTTCATGAGTTGGCCCTAAACCTAATTCTCGATTTTGACGGTCAATTAAAGAAAACATGATACCCTCAGCCTGGGTATAAGTATCCCAGCGACCAGACTCTTGCCAAAGTTCGGCGGGTTGGAGTTGGGGAAGCAAACATTCTTGGGCGCCAGTAGCGTTCATTTCTTCTCGAACAATTGTGGAAACTTTATTGATGACTCGCAACATTAAGGGGAGATATGCGTAAATACCATTACCAATACGACGAATATATCCAGCACGGATGAGGAGTTTGTGGCTAGGAATTTCTGCTTCAGCAGGGTCATCCCGTAAAGTGACCAATAACATTTGAGATAGTCGCATTGTTGCTCCTTGGTAAAAATAATGATTATCTCAGATTAGTTTAAGACATCTAGTATATTGCTAAACAAAAAGCAAAGGGTAATACTTTATCGTTTATTACAATCACAATAGTTTTTCAGATTGTACCAATTTCAAATTAAGTCTGTTTAACTTTAGGGAGAAGTCCTACGCTTCAACTAAGTAGACTTAGTAGATAAATGGTAATTAATATAGTTGACAACTTTCAAAAAGTATGTTCCATAACTTTAACACGGTTAAGACTTACGTAGCTACTACCACTATGTATATAGTAGGGATTTTTTCGTAGGGGTTTTTATGTTATGGAACACTCCAGCCTTGACCGCTACTTTTCCTGTATAGTTTTGTCTTTTATGTTAAATGAAATTCCCTGGAAAGATGAGAGTCTCAGTTTATAGTGATAGCATTAGCGTTAGGTAGTTAACCAAGCATATTATGGAAAAGTCAGAAATTAAGACACAATTTCCTCTTGTGACAGTCGGTGCTTTAATTAAAGGACCTTCTAATCGAATATTAATTGTTGAAACGACAAAATGGAAGGGTACATGGGGAGTACCTGGGGGAAAGGTTGATTGGGGAGAAAGTTTAGAAGCTGCTGTGGCGCGAGAATTTACAGAGGAGGTGGGGTTGAAATTAACTAATATTTGCTTTGCTATGTTCCATGAGGCAATACTAGACCCACAATTTTATAAGGAGGCTCATTTTATTATGTTTAATTATTGGGCAACATCTGATGGAGAAGATGTTGTGCCTAATGAAGAAATTGTACGATGGGAGTGGGTAACTCCTGAAGTGGCTTTAGATTATCCTTTGAATAGTTATACTAGGATACTTATTGAAAAATTTAAGTCTCAAATCTCTTTGTGAATTGTACATAGCTATTTTACAGTTAAAGAAAATTTTGCTTAATTTTGGGTGTGGAGTGTGGTTAAAAAATTGAGTAAAAAAGGATTTTCTGAAGACCTAGGGAGGTTCAATATAGAGTTGTTCAGATCAATGAGGTATAATTTTATTGGTGTGTAAAGCAATGTCTGAATATTGAATTATGTCACTTCCCCTAAAGCCTTGGTAATATAGAGTTGTGACTTTATAAGGTAAATTAAGAATTAGTAGGGAGTTGGAAATAGGACAATGTTAGTATAAATTGAGTGCTAAAAGAAGACTGCCTATTAAGGGCATTGACTGAACTAAACCGTAAGGCATTCGATGAATTATTAGAAGCTTTGTGTGTCTAACTTAAGTTGGAAGCGATATAGCTGCCGCCACTAGGCTCTGCCAACGCTACAATGTAAAAACAAGGACTACTGACTATAGGAGGATGACGAAAAGTCTGGTTGTTAGAGCCTAAAGACAAGCTATTTTTCATATTGTTCTACTTTAAATGCTACCCTACCTTTTATGTGCCTGGATTATTGTTTAACCTACACCGCAGCCGAGCATACTGTTGGATGTTAAGACTACAACTATTACTGGATAATGCATTGGACCGAAGGCAGAGTCTTACTAGAATGTAAATTAGAAGCTATAGAGGAGTTCATAATTAGATTTCCATCTGTCACAGAAGTAATGATTTATGGGACAGAGCGACTCATTCAACGTCCTCAAGACCAATAGAAACAGAAAGATCATTACTCATGTCAAAAAAAGCGTCTAACCCGTAAACATCTAATCCTCAAAATTCGGGAGCGGCGAGTCTTAGTTCTATCGAATTAGAGAGGGTAAGGTTCATGACAAACGGCAGTTGGAGGAAGAGAAAAAAGAAATAAGTTTGGATGGAGCAATGGTGAGGTTACGCACTCCACGTTTGGCAAGTAAGTAAATGGTGGGAATACATTGCCCTCAATATACAAAGTTAAGTCAAGGTAGCATTTTTTAAAGATAATGAAGGATCATGATCTTGAATTAATTGCCAACTTTTGGAAGAAAAGTTCCCCTGCTTAGGAGATGAAGATGACGGAGTATGGGATATCTTTGTGACTCTGGGCACAGCACAGCAACGGGAAGAGATATTGGAGTGCTATCATAATTATGGGAAACTTATACAAAGTGCAAGGAACTCAAGTGCAGCAGGATCAAGTGTGAAATTATCTCTGGCAAGGTCAGTCCACTAATTCTATTCCCTATCTGAGTCAACATCAATAACTGAGGTTCAAATACTTTGATTCAATAGTTGAGAAAGCATCAATCTCGTATTATTAACTACTAGGTCAGGCAAGCTATAGGAGGTTTAGTCGGTTCAGGATCAGTTGAATCTTTAGTTAGGCAAATTGGTTACAGCTATTGTTTCTCTCTTCAAACGTACAGGTATTATATTGTCACTTAATAGGAGCAGCAAATACTATTGAATATATATGAATGTTATTAGGATGTCATAGTACAACTTGATCATGATGGTTTGTTACCTACATAAAATTGGTTATAGAAGGTTTATTGAACAAGAAAAAAATTGTTGGTAAACCTAGGGAAATATCGCCCATATTAGAAAATAAACTTGGAGCTTAACTAGAAAAATATGAAGGTTTTAGTGGTTGTAATTAAATACAAATATGGTTAAAAGTAGTATGTGATATTAATTTCCAATACTAAATAGTACAAAGGTATGTTTATGAGTACTTAAATGTTAAATAAAAGTGCCTCTTCCAGTAAGCATTAAATAAAATTTAACAAATTTTGAAGAGTAAAAAAAATGCCATAATTGCTAGAAAAAGCTATTAAAAAATTTAAATTCTAGGAAAAATCCTGTAAAAAAAATTAGGTTATGGTGTAGTTATAAAGCTAGAAATAGATGAAAAACTATTACTTTAAAAGTAATAACTATTAAAGGAATTAAGGATCAATAAACTCAACAATAGAAGTCTAAATATTTGTATTTATATGGATTAAATTAAACCCAATTTAGGATTTTTTTCTATAGTTTTTAGTTTATATAATTTTTTATTTAAATATTTTCGGATATATTTTTCCATAATTACTCTAATTATTTACATCTAATTCAAGTAGATAGCTTTGGATACTATCAATTATTAAACTTAATTTTTTTTAATAATATTATTATCATATTTAAACAAAGTTATTGTCTAGAATTTAATCTGGTAGAGAGGTTATGATTAGCAATAAAACAAAAGCTGAAGTGGATAATATTTGGAGATTTATCAGACTTTTTGATAAAATATTTAAGGAAATTATACTAAATATTAACCAGGATTTTGTCGCTTCATTAACAGGATGGTAGTTCATCATTGAGGTTTTAGAAAAAGTAGATATAATCAACAATTTTAATTGACCAGCTCCGGCTGATTAAGTAAGTTATCAATAATGGTAGTTTTGACGTACGCATATATGAATAAGTGATTTTTTTACATATATTTAAGAGGAGTATTAAGTATAGCATTTTTTTTTAGAAATAGTATTAAAGGACGTCTATAAATAAAACTTTAAGTGACAAGACGATTTAACATCAGTGAAATCACGGCTATATGAACAACAGATTCACTTACTTCCGCTCAACCCTCCTAATCTTTACTGAGTTCTCTTTGGCGTCTAAGCCTATCTAAAGTTTTCTCCAGCACCCAATGTTGAGATCCAACCTCAAAACTTTCATGAACTTGTAGGCGATCGTGAATTCATTGCCAGACTCCAAGACTCCTGACATTTTCGGCAACCATACACAGTAAAGGCCGGTGGGAAGTCATGGGGTAAGAGTTCCCAGGTGCAACCACTACGATGACTGTAGAGAATACTATTAACAACTTCTGGTAACTCTACTGTTTGTTTCCTTCCTCTGGATGTTTCAGAAAAAGCCATAGCTAGCATGGGAGCTATCATTTGCCAAGTAGCGATACCTTAGCTCTTTGGAATAGTTGAGAGCGAGCCATGTTCTCAATGTTTCAGCTCTAGTTGACGAGTTAGATTTTCTCTGTTTTACTTACTCCTCATTTTATTTTAATTTTTTTTTACAGATACCCTCTTAAAATGAGCTTACCGTGATTAATTAGCTGTAACAAATTCCCTACCTTTAGTCATCTTTAGATGATTTTATCTGTCAGTACAAAAAACTTATTTTTTTGGATATTAAAAGGCTAAAAAACTGATTATATTTTGTCGATTTTCTCCAAATATAAATATTAAATTAATTTTTTATAGGCACTTAATAAAGACATTATAAGATCTTATATATAAATACTTAGGAAGTGTCAAAATATGCTCATCAAGAACAATAAAAAAACTTGATTCCAGTCCCTTTAAAATTTGTGATGGCGGTTTTAAAGAAAAATGGTTAGTTGTAAAAATTTGGCTGCCATTTATTAAACCTGTTCTTATCTTTTTTAAAGGTTATTGACCTAACATTAGTAGTAAATTATGGATAAATTAAAAGGACGAGATTTATTAAGTCTGGCAAACTTGAATTCTGAAGAATTAAAAGAAATTTTACAATTAGCAGCCCAACTAAAATCGGGTGAAATAAATCTTAAATGTAATAAAGTACTAGGATTATTATTTTCTAAAGCATCTACAAGAACCAGGGTAAGTTTTACCGTAGCAATGTATCAATTGGGAGGTCAAGTTATTGATTTGAATCCTAATGTTACTCAGGTTAGTCGGGGAGAAAGTTTGGAAGATACTGCTAGGGTTTTAGACGGATATTTAGATATTTTAGCAATTCGTACTTTTGAACAAAAAGACTTAGAAAGTTTTGCAAATTATGCAAAAATTCCTGTTATTAATGCTCTTACAGATAGGGAACATCCTTGTCAGATATTAGCTGATTTATTAACTGTTCAAGAAAATTTTGGCAAGCTAGATGGAATAACTTTAAGTTATTTTGGTGATGGTAATAATGTGGCAAATTCTTTACTATTAGGTTGTGCAATGGTAGGAATAAATGTCAGGATAGCAACTCCAGAAAATTATCTGCCAAATAAGGAAATTGTGGAACAAGCAAAGACTATTGCTAATGGTAAAAGTGAAGTTCTAGTTACTCAAGACCCCCAGGTAGCAGTTAAGGATAGTCAAGTGCTTTATACTGATGTTTGGGCAAGCATGGGACAAGAACAGGAAGCGAATAATCGAATTCCTATTTTTCAGCCTTATCAAGTTAATGAAAAGTTGGTAGAAAGTGCGGCAGATGATGTAATAATTTTACATTGTTTACCAGCACATAGGGATGAGGAAATTACTGATGCAGTAATAGAAGGAAAGAAATCACTAGTTTGGGAGCAAGCAGAAAATCGAATGCACGCTCAAAAAGCTTTATTGATAAGTATCTTAGGAAGTGATTAGAGCTTACAAAAAAAGTTGAGTTGTATAGTACTACGCGCAAGTAAAAAGTCAACCTCTTCTTTCCCTCAGAGTTTATTTTTTTAACTAGAAAAAAATTTCTCACGGGGTGACAAGCAAGCTATCAATGTATGTTTGTTACCCCCCCATGAGGTAGGGCCAGCTCATTTTAACAATTATTGACAAATAGTATCTTTTCTAATCGTATTGTCCTGACAGCTTTTGAGATTAATTTAGTGACGAAAATATATTCCAGTTGTTAACAGTACTTTGATATTTTTGACAGTGAAAATGGCTTCAAACCCAACATGGAGAAGGAAAGTACATTGCTCGGGTTAGAAATAGCTCAAACCCAGATATATCAAAAAACAGTTTGATGCTATTTTAAATATATTTTTTACTAAAGTCTCGTTAAGCAATAAAACCGATAATATGAAAATTCTGTGATATTTATAATTCCTTGAAAAGCTTGTATTGCAAGCAGATTATCAAAATATTGATTTGTCAATAAAATTTTAGATGAGCTTGCCTTGCCCCGTGAGTTCACACACTGTTATTTTGAAGTGATACCAATTTTTATAAGTAATATTTATGTTTAATAATACTTTGTTGGTATATTTTTGATTGATAATACAGTTATCAAACATTAAGTATCTTTCTGTAAGTATTGTTTTAGCTATTGGACAATTTTATATTTCACATTTAGCCAAAAATATTGGGTCGGCACAGCTCTCTGTTAGCAGTGTAGTGATCAGCCAATATAATTGATTAGTTCTTGATATTAATATTGAAAATATTACGTTTTTCCAGATTTAAAATTTGAAAGTTAAATTATTGGCGATCGCTACATATAATCAGCTATTAACTATTACTTTTAGAGCAAAAAATTATTGATTTATCCAGAATTAAATCTTAGTAAAAAAAATAGCTTCCTTAACCTTAAAGTCTATTTTCATATAAACCCTGTCCTTCATTCCATAGTCTTATTGTTTAGAGCTAAGAAGTTGAGCGCTAATAGCTAAATAATTAAGTTAATATTCTAAATTACTTACATATCCTAGTAAGTGGTAAATTATAGAGTATTAAAAAATGAATAAATATGGTAAATTCTAAAGGGATTACTTGTTAACTAAAAATTTATGAAACTAATTGATTGGCTAATTGTTTTACTATACCTTATTTTAACTATGTGGATGGGGCTATATCTATCTCGCAAAGGTGCAAAAAGTTTAGCAGACTTTTTTGTTTCTGGGCGATCGCTTCCTTGGTGGTTAGCAGGTACAAGTATGGCAGCTACAACTTTTTCCATAGATACTCCTCTTTATATTACAGGGGTTGTAGCTAACCGAGGAATAGCTGGTAATTGGGAATGGTGGATTTTTGCTGTTTCTCATGTAATTATGATTTATATTTTTGCTAAAATGTGGCGACGCTCGGAAGTAATTACTGATGCTGAATTAACTGAAATTCGTTACGGCGGAAATATGGCAGCTGTTCTACGAGGAGTAAAAGCTTTTATCTTTGCTATTCCTATGAATTGTATTGCTATTGGTTATGCTATGTTAGCTATGGTTAAAGTTGTTGAAGCATTGCAAATTTGGCAAAGTTTAGGTATTGATGCTAATGCCAATAATCTCAAATTATTAAGTGTGATAGGTGTAAGTATATTTGTATTAATTTATGCTGGTTTATCTGGTTTATGGGGAGTAGTTGCTACAGATTTTTTCCAATTTTTTCTAGCACTATTTGGGGCAATTATTGTAGCGTTTTTTGCTGTTAATAGTGTGGGTGGAATACAAGAATTAATTATTAAAATTCCTCAAGTTATCCCAGACAAAGATATTTTATCATTTGCACCTTTTACTATTGGTGGAAATGGTAACTCTTGGATTACTTTTAGCAAAACAGCAGGCATAACTGCGAGTACATTTTTTGCTTATATTGCTATTCAATGGTGGTCTTGGCGCCGCAGTGATGGAGGAGGAGAATTTGTACAAAGATTTGCTGCTGCAAAAAATGAAACAGAAGCAGAAAAAGCAGCCTGGTTATTTAATATAATGCACTATGTTATTAGAACCTGGCCTTGGATTTTAGTTGCTTTAGCTTCTATTATAATTTACCCCGATTTACAAGATAGAGAATTGGGTTATCCTAAATTAATGATTGATTTTCTTTCTCCAGGAATTTTAGGCTTAGTTGTTGCTTCTTTAGTGGCAGCATTTATGAGTACAGTTTCTACTTCTATTAATTGGGGCGCTTCTTTTATTACTAATGATTTATATCGAAGATTTATTAAACCTGATGCTACTCAGGCAGAATTAGTTTTGGTAGGACGACTTTCTTCTCTATTAGTAACAGTTTTAGGAGGAGTTGCTGCATTTTTTGCTAAAGATGTGGCAACAGTATTTAGGTTAGTAATAGCTATTGGAACAGGTTCGGGGTTGGTATTAGTTTTACGTTGGTTTTGGTGGCGAGTAAATGCAGCAGCAGAATTAACTGCTATTGTCGCTAGCTTTTTTGTGGGGATGGCAACTAGTTTATTTCCTGCCTTCAAAATAGAAGATTTTGGTTTGCGAATTATCTTTATTACTGTAACTGTAACAGTTTTGTGGGTGGTAGCAATGTTGATTACACCGCAAGAGTCTGATGCTACTTTAGAAGACTTTTATCGGCGATCGCTCCCCGGTGGTCCTGGTTGGCAACGGCAAAGAGTAAGCACTGGTTTAGCTCCTGCACAAAATTTGGGTAAGGATTTACAAAAGGTTCTGGCATCTATATTATTATTGTTTGGAGCGTTGTTGGCGACTGGTGGTTTCCTGTTACTTAAGCCAACTATTGGTTGGATATTTATGATTATTGCTGTTTTCAGCGGGATGTGGTTGCGACAACTCAATAAGTCTAAAATTTTACCTATGCCAAGACCAGGGTTAGATGATGAAGATTTGTTATAAATGACTTCTGAGAATTTATCCATTTTAAAAATGTTTAAAGTAGTTTCGCTTCTTGTGATGTGAAATAATTACCTAGAGGAGTTCTATGAAAAGTGTTTTCCTCCTACTGGCGTGTCAAGCTTAAAATAGTTTATTAGGGTTAGAGGTAAGAAGTTATGACCACAGACCATCAGGCAATTGATAAAAATTGACAAGAAGAAACAAGCGATCGCTAAGAGAAGATTTGTAAAACAAATCTTAAGAATGGCCTGAGTTTTTAGTACTAAGCCTTGGTAATATCAATCTAATCATTGCAGTTTAAATCAAAGCTTCACTAATCTCAGGTAGTTGTTCATACTTGATAGCTAAATGTCGGTTTTGAACTAGCCATGCAAAAGTTCTCTCTACTACCCATCGTCTGGGTAAGACTTCAATTTTTTAACTATTATACCATTTATCAAAAAAAATGCTCTACTTAAATAGATATGAAAAATGTTGTATTAGTCCCACGGCAAGCCAATAACTCGTAACTACCCGATGTTGGTTGCATAAAAGAATGCCCGAAATTAGTATAACGAAGCATTCATAAGTGGCATCACGACTAAACACTGGATGTAAGTTGATCAATATTTGCTCTAGACGAAGTATTATATGCATCCCGAGAGTATTAGCTGGTCAAATTTAAGAATCATTAACCAGTGTGCACCATTCCCTGACATAAGAGCGGGGAATGTTTTTTTTCTACCGAGAACTTTGTACTGTCTGGTAATAAATAATAGTAATTAATTTTACTTAGGAATTTATAGGTTTTAGCTCTAAGATAGATACAATTCAAGCTCTCCTACAAACTTTTTTGATAACAAAACAGGTTTATGATCAAGAACAAGCAAGATATCCATGCCACAAAACTATCTACTATAAATTTTCAATTACCTTATCAATCAAATCACAACCTTGCGCTACAGTTTGTACTTTTGCCAACTGACCCCGCAACTCACCTGCTCCTGGAAAACCCTTAGAATACCAAGTCAAATGCTTACGAGCTTGACGAATCCCGCGATCGCCTTTATATTCCCATAGTGCCCGTAAATGCTCTTTAGCACACTCCAGTTTTTCTGCTGCAGTTGGTGATACTTTTTTTACACCATTTTTCAAAAAATAATCAATTTCTCCCACTAAAAAAGGATAACCTAAAGTTCCACGGGAGCACATTACTCCATCTGCTCTAGTTTCCTCCAAACAACGTATTGCAGCATCAACAGAGAAAATATCTCCATTAGCAATAACTGGGATAGAAAGTATTTCCTTAACTTTTGTAATCCATTCCCATCTGGCCGGGCCATTATATCCTTGGGCACGAGTCCGACCATGTAAAGTTAACATTTGGGCACCTGCATCTTCCATTCTTTGAGCAAATTCGAGAATATTAATTTCTTGATTACTCCAACCAATTCTTGTTTTTACAGTAACAGGAATAGGAACAGCTTTAACAACTTTACTAACAATTTCTCCAGCTAATTCTGGTTGTCTTAATAATGAAGAACCCCCGCCGTTTTTTGTGATTTTATTAACAGGACAACCCATATTAATATCAACAGTATCAGCTCCTTCTTTTACAGCCATTTCTGCTGCTTCTGCTAAGAAATCTGGACGACAATCAAATAATTGAATACTTATTGGTCGCTCATTATTATCAACCTCCATTATTTGAGGTAATTCTTTTACATAATGTAACCCTGTAGCATTTACCATTTCAGTGTACATCATTGACTCTGGAGCATGACGACGTACTAGACGACGAAATACTAAGTCTGTTACTCCTGATAATGGTGATTGAAGGACACGACTTTTAACTTCAAAGTTGCCAATTTTTAGTGGAGTAGATAATTTTTTCTTTAATTCAGGAGATAGAATAGTCAT

Protein sequences of DBSCAN-SWA_5

>NC_008312|1962193:2023112|1973697_1974462_+|WP_011611003.1|DBSCAN-SWA
MDERLQKILSQWGIASRRQAEQMIIAGRVKVNGKIVQLGEKAQPDLDNIEVDGLPIRPEARPSPIYLLLNKPMGVISTCSEPRKRSKVLDILNAELRNGKGIHPVGRLDADSTGALLLTNDGRVTYCLTHPKYCLSKTYQVLVEGHPQESILKLWRQGIILSGKKTLPAEVKVLKECNSSQTLLEVVISEGRNRQIRRVADKLGHRVLKLHRTAIGQIKLQLPGESVLPIGHYRQLKDFEIEFLDDQIIESKFS
>NC_008312|1962193:2023112|2016582_2016810_-|WP_011611022.1|transposase|DBSCAN-SWA
MIAPMLAMAFSETSRGRKQTVELPEVVNSILYSHRSGCTWELLPHDFPPAFTVYGCRKCQESWSLAMNSRSPTSS
>NC_008312|1962193:2023112|1994205_1996482_-|WP_011611012.1|DBSCAN-SWA
MEIRYLELKGMSCAGCANKIQKAIENVTGVAECQVNFAIGQATVKFNSQKTNLHKIQESVTNIGFEAQLLQETINLLDKDRENHQIERKMINKVIFGGTISVILIIGSLPMMTGLNLSWIPSWLGNPLIQLILTTLVMIWCGKSFFFAAIKGLKNRYVDMNTLVAIGTGAAYLYSLFPTFSPIFFTRQGLNPDVYYEAAATIITLILLGKLLEHRARKQTSAAIQKLMGLQAKTARVIRDGKEIDIMIEKVKIGDLIVVRPGEKIPVDGKIKEGFSTVDESMVTGESVPVEKKPGDEVIGVTINQTGSFKFEAARVGKDTVLAQIIKLVQQAQASKAPIQKLADMVISWFVPVVMGVAIATFLIWINLTGNLTMSLITTVSVLIIACPCALGLATPTSVMVGTGKGAENGILIKGANSLEVTHKIETIILDKTGTLTKGRPTVTDYITTQGTTNENEIKLLKIAAAVERKSEHPLATAIVEYAKGQGIKFPLPEPERFEAISGMGVQGIVFDRLVQIGTDRWMNELGIEITNFLNYQDKLEADRKTTAWIAIDGEIEGIFAIADTLKPSSKNVVQTLQKMGIEVVMLTGDNRRTAEAIGAEVGISKIFAEVRPDQKAETVKNLQLEKKKRRNDHQIVAMVGDGINDAPALAQADVGIAIGTGTDVAIASSDITLISGDLTGIITAIKLSRATIKNIRQNLFFAFIYNTLGIPIAAGILYPLTGWLLNPIIAGGAMAFSSVSVVTNALRLRNFKPKAKV
>NC_008312|1962193:2023112|2001472_2001790_-|WP_011611015.1|DBSCAN-SWA
MAIIEIVILTGLGIVLGAFIVNMLNNRQQQRILDDAFYKLLQLQNGKVSLIQLAAAAKVDAQVAQRYLENQVQIFSAILEIDEQGDTFYKFPNLSLPPVLDQQPW
>NC_008312|1962193:2023112|1971540_1972422_+|WP_011611001.1|DBSCAN-SWA
MSWSRIVSGLVAIAVALGMIIFGGWWFTAGMGVIVYLGQLEYFQLASTKGIVPAAKTTLGLSQVMLVVAALNPNLVDAIFTLAGTIICFYLLFQPKLASIADIASSILGLFYGGYLPSYWIRLRVGFEAQLQISQITLENYEYTSWIDPLSWPSSLTFTLLGFCCIWAADIGAYFVGKFFGRIRLSEISPKKTVEGAVFGVLGSVGVATIGSWYLDWPGSPWTGAVLGLIVGIASLLGDLTESMMKRDAGVKDSGQLIPGHGGILDRTDSYVFTAPLIYYFFTLLLPALKNYN
>NC_008312|1962193:2023112|2019401_2021213_+|WP_011611024.1|DBSCAN-SWA
MKLIDWLIVLLYLILTMWMGLYLSRKGAKSLADFFVSGRSLPWWLAGTSMAATTFSIDTPLYITGVVANRGIAGNWEWWIFAVSHVIMIYIFAKMWRRSEVITDAELTEIRYGGNMAAVLRGVKAFIFAIPMNCIAIGYAMLAMVKVVEALQIWQSLGIDANANNLKLLSVIGVSIFVLIYAGLSGLWGVVATDFFQFFLALFGAIIVAFFAVNSVGGIQELIIKIPQVIPDKDILSFAPFTIGGNGNSWITFSKTAGITASTFFAYIAIQWWSWRRSDGGGEFVQRFAAAKNETEAEKAAWLFNIMHYVIRTWPWILVALASIIIYPDLQDRELGYPKLMIDFLSPGILGLVVASLVAAFMSTVSTSINWGASFITNDLYRRFIKPDATQAELVLVGRLSSLLVTVLGGVAAFFAKDVATVFRLVIAIGTGSGLVLVLRWFWWRVNAAAELTAIVASFFVGMATSLFPAFKIEDFGLRIIFITVTVTVLWVVAMLITPQESDATLEDFYRRSLPGGPGWQRQRVSTGLAPAQNLGKDLQKVLASILLLFGALLATGGFLLLKPTIGWIFMIIAVFSGMWLRQLNKSKILPMPRPGLDDEDLL
>NC_008312|1962193:2023112|1962193_1962499_-|WP_011610992.1|transposase|DBSCAN-SWA
MTEIELIVDSTEQDIFRPKNDGKQKKYYSGKQKSHRLKNQIIITDNGKKIVDVIVGERGPESDIILFKKQQKKFDKEQRFQGDKGYQGGSRIDRPKKKNKP
>NC_008312|1962193:2023112|2008630_2009329_-|WP_011611019.1|DBSCAN-SWA
MKKQNQTLNLSVSIVASVCALAVVVGGGIALWTNLQLTTKKTSNNPQTLTDLPTQESPLQTLPSVPSDTIKSPNSQKFPLSIKSEPLAVTEKTVEVYWVKDTATGISLASSPVKIKEIDEPEAILRAAFDLLLSRPENTYVVSAIPEGTKVQALTVENNGVYIDLSEEFTYGGGSASMIGRLGQVIYTASSLEPDVKVWIFVEGKPLEMLGSEGLEVSQPITRQNFQQEFQF
>NC_008312|1962193:2023112|1997563_1998322_+|WP_011611013.1|DBSCAN-SWA
MNNQTAIYCHNLNKIYANGTVALQNMNLTINQGEFLTIVGPSGCGKSTVLRLIAKLSDVTSGKIESNINQKKHELAFVFQEPALMPWSQVIDNVYLPLKLAGRSLREARTIVQEAINLVGLDGFECSYPRELSGGMKMRVSIARALVTQPKIVLMDEPFGALDEMTRNKLNSDLLGVWKKRNWTVVFVTHNIYEAVYLSQRVIVMAARPGRVVADVKIDATYPRSEDFRMSQLCNDYCRKISNYLKMAVSNS
>NC_008312|1962193:2023112|2011161_2012967_-|WP_011611020.1|tRNA|DBSCAN-SWA
MRLSQMLLVTLRDDPAEAEIPSHKLLIRAGYIRRIGNGIYAYLPLMLRVINKVSTIVREEMNATGAQECLLPQLQPAELWQESGRWDTYTQAEGIMFSLIDRQNRELGLGPTHEEVITTIAKDIIRSYRQLPIHLYQLQTKFRDEIRPRFGLMRGREFIMKDGYSFHADEESLKKTYQDMDKAYRNMLRRSGLQFRAVDADSGAIGGSASQEFMVLADAGEDEILYTQDGKYAANMEKAISLPVDVEASPFDTYDKLETPGTETIEKMCEFLHCSATNIVKNVLYQAVYDNGISVLVLVSIRGDQDVNDVKLLNELTRLAGNYEAKTVLALSVPDVEAQKKWAAKSLPLGYIAPDLSDDYITSSKQVSPKFLRMVDKTAVYLTNFATGSNELGNHIVGANWGQEFALPKLVVDVRKAKKGDRAVHDPSKTLETARGIEVGHIFQLGTKYSEAMGATYTNEQGQEVPLLMGCYGVGVSRLAQAAVEQSYDKDGIIWPVAIAPYHVVICIPNIKDTQQIEVAGNLYKELNEAGIDTILDDRDERAGVKFKDADLIGIPYRIVTGRSLKSGKVELIERSTHQCQEIVVAQVLSTLKDLIEKALK
>NC_008312|1962193:2023112|1963527_1964373_+|WP_076611779.1|transposase|DBSCAN-SWA
MPSPYSYDLRQKVIKAIDGGMSKTQVSSIFKISRNTINTWLHRRRETGDIKAKTGYQKGYNPKIPDLEQFRKFAQINGSKTQKEMADEWPDKVSDRTISKALKKLVIQEKKTYGYRERDEDKRKKFLAKIRDKRPEQLVYIDESGMDNREDYGYGWNELGKRYYDLKSGKRSLRVSIVSGLCEGKLVAPLTFEGSCNRVVFEKWLREKLLPQLKTGQLVILDNASFHKSQKVRELIESVNCELEYLPPYSPDLNEIEHYWFPIKNRVRKSEGTIENFRIES
>NC_008312|1962193:2023112|2000614_2001211_+|WP_011611014.1|DBSCAN-SWA
MTSEKESSNQPIIDNSTTPWWLKIWQEQKENIKVVAIALFLSLLIRIFIAEPRYIPSDSMMPTLKVGDRLVIEKISYNFYPPTTGDIIVFEAPQQLQPYGYTKNQAFIKRIIGLPGDTIRIENGTVYVNDQPLTENYIAEPPEYALPTSIKIPEDKYFVMGDNRNNSNDSHVWGFLPRKNIIGKAVFRFWPYQRLGSV
>NC_008312|1962193:2023112|2013435_2013852_+|WP_155994650.1|DBSCAN-SWA
MKTQFPLVTVGALIKGPSNRILIVETTKWKGTWGVPGGKVDWGESLEAAVAREFTEEVGLKLTNICFAMFHEAILDPQFYKEAHFIMFNYWATSDGEDVVPNEEIVRWEWVTPEVALDYPLNSYTRILIEKFKSQISL
>NC_008312|1962193:2023112|1983691_1983835_+|WP_081432529.1|DBSCAN-SWA
MFFQGKAIENLIAQEVKIEYFNDDKLGLVLEQLYPRGLNHIFISMVL
>NC_008312|1962193:2023112|1989719_1990229_-|WP_011611010.1|DBSCAN-SWA
MAKPSPTNLGNEPQAAKVRQLRKLSDLLDNAIGVPGTSLGIGLDPVLGLIPGGGDVLGGLISIYIVFSASTMGLPKNILTKMVTNIVFDSLVGIVPIFGDLFDVAWKANSKNMDLLESHLASSPVHKKADNWFIFILLGCLILFVIAMGILGVFIISLLVKIIEFIIPG
>NC_008312|1962193:2023112|1975138_1976026_+|WP_011611004.1|DBSCAN-SWA
MVNLTAIKNLKKSFSFVPLRQRFNRRKKISFEEKQSQALKDIGDKLKMFRNKHSICLKRVAVVTMIRINLLEAIEEGNLKELPEPVYIQGMIKRYADAIGLDGEELANSFPTAKVQEITIKSLPNLSMLQLRPYHLYFLYVLLVILAVRLLPYVNNSYYIWIRDGITKSEKQQYERENEVNVLPPVSQKNRKTEGRSSDQTTQKSDKQNDGQPVVLSVIAKEESWVSIKIDGKVAFEGTLAQGTQKTWSAQKQLVFFAGNAGGIIIPIDNGQNMQLGKPGEVKEVVLTSTNTQIQ
>NC_008312|1962193:2023112|1987175_1987925_-|WP_011611009.1|DBSCAN-SWA
MVIISRIKFLLIVTISLIIFLYFPNLTFQKVSAQLILSPEINALDASFNKPKIYSFVESGFNYSQQLYGKPRIPVKKVNLNLNTTPLTSLDNANQGEFTIYLNRKPSEYAFHGQLAHEIFHLLNAQLLDCYAEGLATLFAEKLLTRNNLNWSGWEEYFQQGFEPFYGLSYFMMKEVSDTAGETNMSRLLEFVVYNNSMKKWMHINISEWLSSMSDNVKIEVEEVINKHITQVQQVTESNNQMYSCLEPS
>NC_008312|1962193:2023112|2014901_2015096_+|WP_155994334.1|DBSCAN-SWA
MEEKFPCLGDEDDGVWDIFVTLGTAQQREEILECYHNYGKLIQSARNSSAAGSSVKLSLARSVH
>NC_008312|1962193:2023112|1977140_1978658_-|WP_011611005.1|DBSCAN-SWA
MLLSRSSGILLHPTSFPSPFGIGDLGQEAYNFVNFLKNSGQKIWQVLPLGPTGFGNSPYQAYSAMAGNPLLISPDKLKDEGWLSEEDFSNIPEFPRDKVDFDSVAQVKSSLLKTAYQNFQKYASEEKKETFNQFSNSKAFWLDDYAFYMALKEAHEGASWHTWDQDIAHRQPQALAEWQQRLADKIQYHKFLQYLFFQQWDQLKSYANQQGIKIFGDVPIYVAHDSADVWSHPEIFSLDSQTSEPSLMAGVPPDYFSETGQLWGNPVYQWDKLEQEDFFWWVQRIQSMLDIVDLIRIDHFLGLVSYWAVPQGETTAKNGTWITAPGRAFFKTIKEKLGKLPVIAEDLGVITTEVEQLRDQFEFPGMKILHFAFDSGSDNLYLPCNYNSANWVVYTGTHDNNTTVGWFNKRSPQEQERVYRFVGNSWGHGIHWDLIRLAMSSVAYMAIFPLQDILGLGEEAIMNQPGVPDGNWSWRYRSEMLTSDISDRLKEVTDIYGRTPTNNED
>NC_008312|1962193:2023112|1985586_1986489_-|WP_011611008.1|DBSCAN-SWA
MIIRNKNWLKLLLTLKGSIVPQVWQRVAVAMIFSAIITILYKIGFTSIHQPILVSLIPSVVLGLLLVFRTNTSYDRFWEGRKATGGIIISCRSLSRQIWVNIPEKTPEDTEEKIAVIRLLAGFLIGTKLHLRNESLDLKIRSIISENQYLELKEVNHIPMRIAKWIGDYFRKAYDLNYIDSIQLSTYNQILDSMVKDETACERILNTPIPLAYAIHLKHLLFLYCFALPFQMVAKLSWITILVVGIISFALLGIEAIGLEIENPFGYDPNDLPLDNMCDKLLLELEELLTSDSRKEYLID
>NC_008312|1962193:2023112|1998915_1999053_+|WP_155994333.1|DBSCAN-SWA
MGEWFALPEPSGSKNDLPNVAPPITTVAALIEMLGGFFLSKKGVT
>NC_008312|1962193:2023112|2005047_2005605_+|WP_011611017.1|DBSCAN-SWA
MISSNDFRPGVTIELDGSVWRVVEFLHVKPGKGSAFVRTKLKNVQNGNVVERTFRAGETVPQATLDKRAMQHTYKDSDQFVFMDMETYEETNLSSEQIGERVKYLNEGMEVNVIMWGEQVIEVELPNSVVLEVIETDPGVKGDTATGGSKPATVETGAQIMVPLFISKGERIKIDTRNDSYLGRE
>NC_008312|1962193:2023112|1969871_1970255_-|WP_011610999.1|transposase|DBSCAN-SWA
MIVLTNGKDIVDIEARKLGQISEINFFREIQEKFHQEQKFTRDKAYVGEPAIKTPKKKPPIQELTSKEKSQNKELASERILVEHIIRLLKIFRVAQERFRLNSDKYTQIIMTICGLVILGRGTVILS
>NC_008312|1962193:2023112|2014319_2014499_+|WP_071820553.1|transposase|DBSCAN-SWA
MLEPKDKLFFILFYFKCYPTFYVPGLLFNLHRSRAYCWMLRLQLLLDNALDRRQSLTRM
>NC_008312|1962193:2023112|1983496_1983685_+|WP_011611007.1|DBSCAN-SWA
MLVEVSNIDHLRLLAGIIDEIGMENKINQLLGEELPEKIIGGQAAKGMLLNRLGKVLFILYF
>NC_008312|1962193:2023112|1972785_1973574_-|WP_052845758.1|DBSCAN-SWA
MVSLMNKNLPQLHHISGSDIADQSLDEISTKRKSRIVSRFLSPALQFWLKSQLEQVEQLKVHIEGGDRQIITGQIPRVSLAASNVIFRGLHLTEVKLSATGIRINIGQIIRGKKLKILESFPIFCQIKCLQSDFNSSLKSGLLSQAIVDFLTPLLQSDFIECLEKPIRLYDQKAEIFTGHLSLFANFMSKFDEKIPINLHTSLKLATSCKLLLENFEFQVLQKSNYDLSNTIKVDLGSDVKLQELTLESGQLICQGSLIVKS
>NC_008312|1962193:2023112|1971009_1971150_-|WP_155994332.1|DBSCAN-SWA
MREVSSATGYRLEAIKKIVRCYNHQGQEGLVDSHYQHLGLKGFLCE
>NC_008312|1962193:2023112|1990541_1992458_-|WP_011611011.1|DBSCAN-SWA
MAKVVGIDLGTTNSCVAVMEGGKPTVIANAEGFRTTPSVVAYGKKEEQLVGQIAKRQAVMNTQNTFYSVKRFIGRKFDEVTHETTEVSYKVLNINGNVKLDCQALKKQFASEEISAQVLRKLIDDASKYLGEQVTQAVITVPAYFNDSQRQATKDAGKIAGVEVLRIINEPTAASLAYGLDKKSNETILVFDLGGGTFDVSILEVGDGVFEVLATSGDTHLGGDDFDKKIVDYLAAEFNKVEGIDLRKDKQALQRLTEAAEKAKIELSSVTQAEINLPFITATQDGPKHLDLTLTRAEFEGLCSDLIDRCRIPVENAIRDAKLDKKAIDEVVLVGGSTRIPAVQEIVKKVLGKEPNQSVNPDEVVAVGAAIQAGVLAGEVKDILLLDVTPLSLGVETLGGVMTKIIPRNTTIPTKKSEVFSTAVDGQTNVEIHVLQGEREMSSDNKSLGTFRLDGIPAAPRGVPQIEVTFDIDANGILNVTAKDKGTGKEQSISITGASTLPDTEVDRMVKEAEANATADKERRDKIDRKNQADSLAYQAEKQIQELGDKVPEADKTKIEGLIKDLRDAVAQEDDEKITSLTTELQQALYSVSSNMYQQSGGAPGEGSTPNSDAGSGASSSNATGGDDVIDADFTETK
>NC_008312|1962193:2023112|1968384_1968987_+|WP_011610998.1|DBSCAN-SWA
MPSQLWPYVSPGIPDDLFERLPGIPMSKREVRLLLISYLRLQSDSVVWDIGAGTGTIPVEIGLICPQGRVIAIERDQEVASLIRRNCNRFGVENVTVIEGNAPECLDSLTDAPSRVCIEGGRYIKVILQEVWKKLLPQGRIIATAANLESLYAVSESFADLQVRNIEVAQSALNRLETRGVYQTFAAVNPIFILSGEKIN
>NC_008312|1962193:2023112|2021510_2021627_-|WP_071820743.1|transposase|DBSCAN-SWA
MEVLPRRWVVERTFAWLVQNRHLAIKYEQLPEISEALI
>NC_008312|1962193:2023112|2002255_2003392_-|WP_011611016.1|DBSCAN-SWA
MVNLRNFVMNTCKRLLKTAILGLLLITLSIGISAAWWNGGMTTTRQSRLPQGDPITDGRALLRYALPIENEPVRKIQSSLEDISNRLRGKRWTSVVSDIGTASRVLSINKPKLLASVPESKQPEAEEIIAILDQGIIDIKEVAEAKDGEQVLEQRAKLLTLVGQLEQLMVVGFPFEVPSDFSNLPQLKGRATIDMETNKGSLTLVVDGYSAPVTAGNFVDLVQRGFYDGLEFIRSEQSYVLQAGDPPGPEVGFIDPDSGKYRNIPLEILVQGDNEPIYSFTLEEIGRFRELPVLPFSAYGAVAMARPEAENDGASSQFFFFLFQPELTPAGVNLLDGRYTVFGYVVAGKKVLEELNKGDKIISAKVVAGFENIVEPEA
>NC_008312|1962193:2023112|2017344_2018265_+|WP_011611023.1|DBSCAN-SWA
MDKLKGRDLLSLANLNSEELKEILQLAAQLKSGEINLKCNKVLGLLFSKASTRTRVSFTVAMYQLGGQVIDLNPNVTQVSRGESLEDTARVLDGYLDILAIRTFEQKDLESFANYAKIPVINALTDREHPCQILADLLTVQENFGKLDGITLSYFGDGNNVANSLLLGCAMVGINVRIATPENYLPNKEIVEQAKTIANGKSEVLVTQDPQVAVKDSQVLYTDVWASMGQEQEANNRIPIFQPYQVNEKLVESAADDVIILHCLPAHRDEEITDAVIEGKKSLVWEQAENRMHAQKALLISILGSD
>NC_008312|1962193:2023112|2022107_2023112_-|WP_011611025.1|tRNA|DBSCAN-SWA
MTILSPELKKKLSTPLKIGNFEVKSRVLQSPLSGVTDLVFRRLVRRHAPESMMYTEMVNATGLHYVKELPQIMEVDNNERPISIQLFDCRPDFLAEAAEMAVKEGADTVDINMGCPVNKITKNGGGSSLLRQPELAGEIVSKVVKAVPIPVTVKTRIGWSNQEINILEFAQRMEDAGAQMLTLHGRTRAQGYNGPARWEWITKVKEILSIPVIANGDIFSVDAAIRCLEETRADGVMCSRGTLGYPFLVGEIDYFLKNGVKKVSPTAAEKLECAKEHLRALWEYKGDRGIRQARKHLTWYSKGFPGAGELRGQLAKVQTVAQGCDLIDKVIENL
>NC_008312|1962193:2023112|2006187_2006691_+|WP_011611018.1|DBSCAN-SWA
MQLDLHQLQELLKAIDQTNISELTLKSGDLELVVRKETSSSDRHSLPSSNKSDTISELVSPTVAALETMATSKTSVMPPAAPPTASNKFEEILSPVVGTFYRAPNPDETPFVEVGDQITSGQTVCIIEAMKVMNEIEAEVSGQIMKVLIKNGEPVEYNQPLMLVNPN
>NC_008312|1962193:2023112|1963270_1963474_+|WP_081432410.1|DBSCAN-SWA
MVTCLRTGWKIVPIPKLQPGQVIILDNATFHKSVYIEELVAKQRCEIWYLPPYSPDFNKIERWWFVL

Homologous phage analysis in the prophage region

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_011610992.1|1962193_1962499_-|transposase	transposase	NA	NA	NA	NA
WP_081432410.1|1963270_1963474_+	hypothetical protein	NA	NA	NA	NA
WP_076611779.1|1963527_1964373_+|transposase	IS630-like element ISTer1 family transposase	R4THZ0	Phaeocystis_globosa_virus	3.6e-09	22.7
WP_011610998.1|1968384_1968987_+	precorrin-6Y C5,15-methyltransferase subunit CbiT	NA	NA	NA	NA
WP_011610999.1|1969871_1970255_-|transposase	transposase	NA	NA	NA	NA
WP_155994332.1|1971009_1971150_-	hypothetical protein	NA	NA	NA	NA
WP_011611001.1|1971540_1972422_+	phosphatidate cytidylyltransferase	NA	NA	NA	NA
WP_052845758.1|1972785_1973574_-	DUF2993 domain-containing protein	NA	NA	NA	NA
WP_011611003.1|1973697_1974462_+	rRNA pseudouridine synthase	NA	NA	NA	NA
WP_011611004.1|1975138_1976026_+	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_011611005.1|1977140_1978658_-	4-alpha-glucanotransferase	NA	NA	NA	NA
WP_011611007.1|1983496_1983685_+	DUF4277 domain-containing protein	NA	NA	NA	NA
WP_081432529.1|1983691_1983835_+	DUF4277 domain-containing protein	NA	NA	NA	NA
WP_011611008.1|1985586_1986489_-	hypothetical protein	NA	NA	NA	NA
WP_011611009.1|1987175_1987925_-	hypothetical protein	NA	NA	NA	NA
WP_011611010.1|1989719_1990229_-	DUF4112 domain-containing protein	NA	NA	NA	NA
WP_011611011.1|1990541_1992458_-	molecular chaperone DnaK	E5ESM6	Bathycoccus_sp._RCC1105_virus	3.8e-147	50.0
WP_011611012.1|1994205_1996482_-	copper-translocating P-type ATPase	A0A218MNH6	uncultured_virus	8.6e-106	34.6
WP_011611013.1|1997563_1998322_+	ABC transporter ATP-binding protein	G3M9Y6	Bacillus_virus	2.7e-32	36.9
WP_155994333.1|1998915_1999053_+	hypothetical protein	NA	NA	NA	NA
WP_011611014.1|2000614_2001211_+	signal peptidase I	NA	NA	NA	NA
WP_011611015.1|2001472_2001790_-	hypothetical protein	NA	NA	NA	NA
WP_011611016.1|2002255_2003392_-	peptidyl-prolyl cis-trans isomerase	NA	NA	NA	NA
WP_011611017.1|2005047_2005605_+	elongation factor P	NA	NA	NA	NA
WP_011611018.1|2006187_2006691_+	acetyl-CoA carboxylase biotin carboxyl carrier protein	NA	NA	NA	NA
WP_011611019.1|2008630_2009329_-	hypothetical protein	NA	NA	NA	NA
WP_011611020.1|2011161_2012967_-|tRNA	proline--tRNA ligase	NA	NA	NA	NA
WP_155994650.1|2013435_2013852_+	NUDIX domain-containing protein	NA	NA	NA	NA
WP_071820553.1|2014319_2014499_+|transposase	DDE transposase family protein	NA	NA	NA	NA
WP_155994334.1|2014901_2015096_+	hypothetical protein	NA	NA	NA	NA
WP_011611022.1|2016582_2016810_-|transposase	transposase	NA	NA	NA	NA
WP_011611023.1|2017344_2018265_+	ornithine carbamoyltransferase	Q84489	Paramecium_bursaria_Chlorella_virus	3.8e-20	26.9
WP_011611024.1|2019401_2021213_+	Na+:solute symporter	NA	NA	NA	NA
WP_071820743.1|2021510_2021627_-|transposase	transposase	NA	NA	NA	NA
WP_011611025.1|2022107_2023112_-|tRNA	tRNA dihydrouridine synthase DusB	NA	NA	NA	NA

Sequences of DBSCAN-SWA_6

Nucleotide sequences of DBSCAN-SWA_6

>NC_008312|4685402:4740814|DBSCAN-SWA
TATGATTGAACCTTTAGGAGCTAAAGTCCTCAATCTATCTAAATGCTCTCCTGATTTTAACCCTATTGAATTATGGTGGTTACAACTAAAGTCTTTTATAAGCAGTTTTTATCCCACTACAACAGAAATGGTTGATACGGTCATTTCTGTTGCATTTTAGTTAAGGGTACCTTGTCAAAAAATATGTCAAAAACATCATCAAACTCTTATTTAGTAAAGGTTTTACATGTAATCAACTTGTTCCATGACACATGACATATTCAGCTTTAATCCTTTTTTAGCTATAGCTTTGTATTTCCCTCGCTCCTACTAGCAACTACAGGTATTTTCTCGGTAAAAAATGTCAAAGTACCATTAATATTCTGCATTTAAAAAACTTGTTTATTAAGTGCTGTTATTGTAACTCATAACAATAAGAAGTGGTGTATAAATTTAAAATATATTAGTTGTTTGATTAGGCAAATTGAAGATTTTTTTTATTAAAGATAAATCTATAAATTCTGAACATCAGGTAAATTAAAGAGCATAAATTGGTGCGGTATTCCTAAAAAATTAAGTTGTTGACCAGTGCTTATAAAACCTATTTTTTCATAAAACTTAGATGCACTCAAACGAGACATTACTCTCAAAGATTTTAATTGTTTTTCTTTGGCAATTTCAATGATTTTTTGAATTAAAGCTGTGCCTACTCCCTGAGATTGAAATTTAGGTAAAACAGCAACATATGAAATACTTCCTAGTTCTGTAGATAATTGTCGCAGTCTAGCCGAACCAATAATTTGTTCCTCATAAACAGCAATAAAATGTAGAGAAGAATCATCATCGTCAGACTCATCTTTTTCTGTTCCTCTTTCCATATCTATCGGTTTTCTTAAAACTACCCAACGTTGATAATACATATTTTCTTTTTCTTGTTTGTTTTGAATTCGGCTAATCTTAAACTTTAACATTTTTCAATTTTAATTAATTCAAGGATCTCTATTTGATTTAATCTAGATTTTTATTTATGGGTTGCTAAATACAATTTGATAACTAATAAAGCAATCACTGAAAATACCCATAATGAAATACAATTCAGAATAATGAATCATTAATATCTTATTAATAAAAATAGACCACTTTTATACAATTAAATATAATGTCTATAAATTATAGATGGAATAAAAAGCAGTAAAGTAATATAATTAAATAATTCCATAACTATTAGCTACAATTAACCCCATCTCTGAGTTTTAAGTAGAAACTACTTAGACCAAGCTGGATGAGATAATATAGACGCAAACATTCGTACTCCACGGAGTAAATTAGAAAGAGGTAGATGACCTTTTGGAGCACTTAAATTCCAAGTAAATTCATTAGGGTATCTACTCCAAGTATTGCCATTTTTCCAGCCAATTTTTGGTAGAAACTTATCCCAATTTTTCCCTGATCCCAACCAAATTTCTCTCTGTACGGAATAGCCAAATTTACCTTCTGAATAAATTAACCACATGTTATTAATAGTTTTCATATCTGGAATTGGAATACTATCTACTTCTGAAAAATAAAGCCACTTTCTTTGTATCGCTGCTTCTCCTACTAACTCACACAATTTTTGCATTGTTAATTTATCAGCTTCTAAAAAATCTTGATGGGCTAATTTGACTTGTAAATGACTGTAGTCGATATTAGATGCTGAATTGATTGGTACAACTCCTAAGGGAAAGTTTTTTTGTATAAATTCATCAACTTTAGATGACTTAATTTGACGTAAAACTTGATATATTTTTCCCTTAACTATAGTTGGCGAATCTAATTTTTTCTTCTGCAAAAACTCCATGAGAATTTCTACACCTTCATCTCCTATTTTTGCTAAATTAGGAATTACCTGCAACTGTTTTTTTTCAGAACCAGATTCTAGTTGATACTCTAGTTCAGATATATTAAATGAAGGGTATTTTGTAAAGTTAGTTTGTGATTCTGTCATTTCATTTATTAGTTATTAGTTATTAGTTATTAGTTATTAGTTATCAGTTATTAGTATATCTAGGAGTCATAATTATATTCATAATTCTGTAGAACCTGTCAGTCAATTAATGGGTTTCAGAATTCTACAAAATTTGATTATTTACTAGTATTGAATTAGTAGTCATTCCCCTATCTCCTACTAAGATTAATTCTGACGACTCCTTGTTCAATAATATTTTGACATCCTCCCCGGCTATTAGGCATGGGGTAGGGGGTTATTGTAAACCGAAACTCCAATACAGTTTGACTTTTAATTGACTTCTGCAATTTTTGGTCGTGAGGACGAAACTTGCACTTGCCTTAGACTTACCTCCACGTCCGTTTTTTTCTGGTGACTGCCTGCCTGCGACTAATATATCTACTGCTGCATTTTGATCACGTTCGTGTTTAGCACCACAGTTGAGAGACTCCCATTCACGAATTAATAAATCTAATTTTCCTCCTTTAACATCAAATACAGCTAGAGTAAATTTGAAATGTTAGTTCTCAACGTCGAATTACTCTATGACTGCGGCTATATTTTTTTGCCTTTCCTTCTAACAAGGTTTCGGCATTACTTCATAACCATTCATTAGAGACCCAAACCTCTTGGGGACGGGTTACGCTTTTGACCACTAAAGAAACATATAATACCTCTACAAAAATCAATTGTTTGGTTTTCACTAATTATTTTAGTAGATAATTTATCCATAAAATCTGTTTTTATGTTCTTTTGTTTCCCATGAAATTTAGCAATTTTAACTTGTGCATTTTTATATTGTTTAAAACCCCCTACTTTTTTAGATAAATACTTACCTAACACGTTACACAGATCCTATGAAAGAGGGCACTTACTGATTAATCTTTTTCTTTAAGAGTTTTTGTGCATGAATTTTATTACTTTTACTCAAAGTAGCAAAAGTTTTAATACCTAAATAATTATCTACTTAATCATCAGTTTTAGGAATGTTTTCTAGATTAATTTATCTTACAAAACTTAATAAATATCTATTAGTAGAGTATTTAATAATACTTACTGATGATACTTAATCCTTACAACTTTCTCAACCAAACTACTCTTAATTTCCAAACTTTAAGCTATATTAGGAAATTTATGCTGAATAACTTTCAACCCTGACCGGACCTAACAGTTTGCATATAACTTCAAAGTTTTAAATTTAGGAGATTTAACAGGTTGACTTTTAGTTGATCTAAAAAAGTTTTGATAGACTTGGTTTAAATCATTTACACATTACTGCAATGGTATAGTAGAAACTTATGATAACTATTTTCTATCTTGAGTCTTTTTAGCTTGAGTAATAAACTGTTTTTCTAGTGTAGCGGGGGAGTTAACAGGCTTCTTCTCTCCTAATAATTACTTTTTATAATCATAAAGCTAGACTATCATTCAACACAAAATGGACACAGCTATTATGAGCTTTGCACTATCAGTATTTTCGCTTATGGCCGATGTTTTAAACCGAATTTTTTGGTAAAATACTATTAATAATTCCAGTAGTAGAAGTTGGCACTTCTATTTGAATTATAGATACTTTACCACCATAATTTTTTACTTTTTGAGCTTCTGGTAATGTTTCAACAGAATAATCGCCACCTTTAACATAAATATCAGGTTTAAGTCGTTCTATTATTTTAGTAGCAGTAGTTTCATTAAAAATTACTACTCCATCAACCGGTTTGAGAGCTGCTAAAACTTCAGCCCGTTGGGTTTGTGGTATAATTGGTCGCATTGGGTATCCCTCTTTTTGGGGTTTAAGATTTTGCACTGACCAATCACTATTTAATCCTACTATAAGCGATCGCCCTAGAGACTTAGTTGCCCACAAATAACGAACATGTCCAGCATGAATTAAGTCGAAGCACCCATTTGTAAATACTAAAGGTCGCCAAAAAGTTGCTTGAGAATTAATTAGTTGTTCTAGTTCAGTTAAATTGTATAGGCCAGAAATTAGTTTTTGGGAGTCCATTTTTTCTTATGTCCCTTGATACTTCACCTTAATTTATATCTTCTTCAGTAGGTGTTTGATATTTATGTTCAAAAGCATAATGAACTAAACTGGGAGAGAAAATATTTCAATGAGGGCTTTCTCATGATTTTACTCAAATGAGTTTATACATTTCGAGGACCAAGGATCAAGCGATCGCTAATCTGCTTATTTGTCAAATGTAGAAATAGAGAATACAAGTATAGCAAAGTTGTTGATAATTGGTATAATTCGATAGCAATGGCCTGGAAGTTTAGGAATATATAATCAAAGAGAAAGAAGCATAAAGCTACAATTAAACTCATCCAAAACAAAACAAGTCTAATAATGAGTTAAATTAGAAATAAAAATACTAAATATAATTTAAAGTAAAATGCCAAAAATTTGGTAAATTAATGTTAGTAAATATCCCATAAAAAAGTAATGCATGATGTAAAAAATGATTAAGTAAGGGGATGATAAAAAGCCCTAGTCAATGGTACTATCTGTCCAATATCCGAGAATATAAGCACTCAAAATTCAAGATAAAAAGGATGAATTGATTTAATTTATTTAGATAAAAGTTAGTTTTTTTGAAACATTATTCCTCTTAATAACTACTAGAGATAAGTAGAAGAATAACTTGTAAAAGTTTTAAGATAAAGCAATAAATTTTATGAGATTAATGAATTGCAAATAAGGAATTATCGCACTTCCATAGTCAAGGGAAATCTTAATAGTAAAGTATTGATTAAGCTTTGGAAAAATTTATTCATAAATTTTCTAAAGAAATTTATTTGTTATTAAATAAGGGTCAATTAATACTAATGATAGTATACTGAACAAATTACAATAATGGAAGTAAAAAAACTAAAAATATTTGGGTTGCTTACCTAGTAACAGAAACCAAATATAATATAAATAGGAGATTAATTAAAAATGAATAGGTTAAAGTAGAAGCTTCAACTGGAAAAGCTTACTTAAATCTATTAAAAGAGTTCTTAATAAAAAACAGAATAGAATAAGCATGCAATGAATCTTGCTTATGCACTTACTAAAAAATAGCAGATGAAATTTCTCATTTTTATTCAAAATTTTACTTAATTTATTGAAATATTATTATAAAAAAGTGAGTGATTTAAATTAAAATAAGAAACAATATTAAATAGTATATATACCAAACCCATAAAATCTAAGTTTTAAAGAAAAAGTCTAACTTTGTTCATTAATAATCAATTAAAATTATATAACTGAATAATTATAGTTTACACACAAAAGCTGAATATTGAGATAAGGTTTGGGAAAAATAGACAATTAGTAATAGTTGCAGAATATTAATTTTTATATATTTTTCAGGTAAGGGAAAATTTCAAGTGAGGGAATATGAATTGAAATACCAGTACAATATAATTTACCTATTCTATACCTATTCTAATTATATGGGGTCTTTAGAAGGTAAATAATTCAGCTTGTATAAATGTGTAATTAATTGTGTGTAACTGCTTAGTAATATAGGCACTTTTTTATGGGTAATACCACTTAAACTGATTGATCATCATAATTCTGTATTTATTCAACCAACTATAATTAGGACTTAAAAAAAATCTAGTAAAAATTAGAGATGGAAAAATCTGATGGGCTGTGCTTAAACCCTGTCATAATTGTAAAAACAGAATGCTATTTTGAAATGGGGAAAATATATTTCCACCATCAGTAATAGATTGTATCTTCAACATTCTTGATCTACTATTTCCAGTAAACTATAACTAAGAACTCAGTAAAATCCCATGAAAGCAACAAGTATCCGTCAATATTCCTCAATAGCTGCTAGGACTCTGATAATAGTAGGAGTAATTATGATTTTGTCCTCTATACTTGACTTTATAGTCCTATCAGTTCCTTCTAACATAGAGAACATATACAGCAAAACATGGCAAATAAATTTAGCAACTCAAATAGTCGATCGGGGGATCATTCCTATGATAGGAATGGCCTTATTATTCACAGGTTACTGGGTAAGAAGTAATTCCGGCCTTCAAAATAACTCTACATCTTCAATATTAGATTTAAGATTTTGGGCACTTTTACTAGCTAGCTTATTAGCATTGATATATCTACTACTATTTCCTTTACACTTAAATAATACTCGTTTAGACAAGGCTGAGTTGATTCAACGCATCGAGCAACAAGCAAGCCAAGCTGAAACACAATTAAAAGCTCGTCTAAGTAGTAATGAATTTAAAAATCAGATCCAGGAAAGACGAACTCAATTGAAAAATCAACTGACTACCTTGCTAGAAGATGAAACTAGGTTAAATGAAGCATTAGAAAATGAAGAATTACCAGACCAATTAAAAACTTTATTAAAAACATCAAAAACAAACAACAATTCTCAAGCTATCAATGAATTTATCAATGATCAATTCAAACAATTACCAAATCAACTTACAATGAGAATTCGTGATCGTAAGCAAGAATTAGAAAAACAAGCTAATAGAAATTCTTTTAAATCTAGTCTCAGAACAGGTATAAGCAGTTTACTTTTAGCAGTCGGTTATATTATGATTGGTTGGACAGGATTAAAAAATATGGGAATTATTAAAGGTAAGGGAAGTCGCCAAAATCCCGCTAGGTAATTACAAAGCAGTACATCACAATTACAATAGAAATCAGCAAAAGTAAATTAATAGTACTGAAAGAGAAAGTGTTAACTTAAACTTAATGCCCAATACCTTACCAATTGGATATTTATTTATAGCAGATTTCATCTGAGTAAGCTATAGCTGTTGCGGTCAAGATGCCGATGATAAAAAGGTTTGATTTAAACTCCACCGACCATGGGATGTCTTCTTTAATACTTGTACTTCATACACTTAGAATCTGCTGTAATTTAATTACCTAATTTAATATTTAAGTAAGTACACAAAATTAGTTACACATCTATACAAACTAATTATTTGCGTTTTAAAGATTGCAAAGAACTAGAATAAGTAAATAATTTTGTTTAAGTACTTATAAAAGAGCAATTGCTAAAATTAATAAAATGTTCTCAATTTATATACTGACTTACAATGAGGAAATAGATATTGCTGCTTGTATTAAGTCAGCAATGCTGTCAGATGACATTATAATAGTTGACTCCTTTAGTAGTGATCGGACAATAGAAATAGCTCAATCTTATCCTGTAAGAATAGTCCAAAACAAATTTAAAAGCCATGGACAACAAAGAACATGGATGTTACAGGAAATTAGTGCCAAATATGAGTGGGTCTATATCCTAGAAGCAGATGAACGGATAACCCCAGATCTATTTAATGAATGCCTAAAAGCAGTCCAAAGTGAAAAATATATTGGGTATTACGTCGCAGAACGAGTGATATTTATGGGAACTTGGATTCGCCATAGCACACAATATCCCCGCTATCAGATGCGCCTATTTCGTAAGGATAAAGTCTGGTTTAGTGACTATGGTCACACAGAACGAGAAGTTTGCGACGGTCCCACAAGTTTTTTGCAAGAAACTTACCCCCATTATACCTGTAGTAAAGGTATGTATCGTTGGATAGAAAAGCACAATCGCTATTCTACAGATGAAGCTTCTGAAACAGTTAAACAACTAGAAAAAGGAAGCATATCTTGGAAAAGCCTATTTTTGGGCGGGTCTGAAGTAGAGAGAAGACGTGCTCTAAAAGATTTTTCCCTACGCTTGCCTTTGAGACCAATAGTTCGTTTTATATATATGTATATTTTTCTCAGGGGATTTCTTGATGGCCAAGCTGGATTAGCTTGGTGTACCTTGCAAGCTTTCTATGAATATCTCATAATAATTAAAGTCTGGGAAATGAAAAATATGCCTGCACCATCATTAACTTCAGCTGTCGATACCAATTCGCCAAAATTAGAAATAGAGGCACAAAGGTGAAAGTTAAACTAAGGAATCCCATTTTCAGTTTCCCTTTATAGGGTCTGCTTGTTTTCAGAACTGGAAGTCAAGCTTTTACTTCATCTGGCTTTCTCTGCTAAATGTCCCTTTCCACGGGTATACTCAAAGACCTCCTACCTCAGACCTAATAGGCTTTTCCAAAAATGCCGATTTTGGAACGGCGGAGCAAGGAGTTGATAACCTTGTCTGGAGATGTCTAATAATTCCTAACGGTTAACTGCTTGTATATCCTTGGCAGTTTTCGAGTCATGGGAGTATTGTTGGAGTAACTACTTATTTTTGATTGCGTTACTACCCCACCCTCCGAACTTAGAGTAACGTGGTCAACCTCAATACTTAACCAGGACTTGTAACGCTCTGTCATACATCCCTAGGATGCCTAACGGGCGCTTTTCGTCTTTACCTTAGTTTGATATTGGTGACTCTTTCAGCTCGCCTTTAGGTTTTATATAGATTTACTAATTTTAGTCGCTGCTTAGGTGGGAGACTTTTAATTCCATCTATCCCGGCGGTTTTCTTATCTTGGTTTTCCTGACACACAAGTCTAACAGCTAGGAACAAGGGGTAATAACTTTTGGTCAGAAGTCTTTAGTATTTAGAGTGTAAAGCGGATTTCACTACGGTTGGACGCTCTGTAAATTAACTTTTGCAACTTAAATACCTTCTTCAATAGCCTTTTTCCAGTCTATGTCCTTCCATTTAAGACTAGGATTGACACTTGCCTAAGACGGTAAAATGTTCCGTGTCCCATCATACCCTTAAAAAGGATTTTGATTTTTTCTCTGATATTTAAGGTGAAAAAATCAGAGACTCTGTGAGAAAGTTTAGTAAATTATGGGGAGATATTTTAAGAGCTGTTTAATCTTACTGGGGGGACTCCTCTTAAATATTTCTTTAGAAAAATTACCACTACTTTGACAGAGCAACAATTATACTAAAAAATCTAATGCACTATTTTTAGCTGTTTCAGTCTACTACTGTGCATTATTAACAAATACTTATAGCGGCTGATTCATAGCTGGAAAAAAAGTAAATGTTAAGTTCAAAGTTTATCATTAAAAATACATCCAGTTACAGTCGCAAATCTACACCAGAATCTGAGTAAATTAAACTATGCATCTAAGCGAAATTACTCATCCTAAACAGTTACACAATCTTTCAATTCATCAACTAGAAGAAATTGCTAGACAAATACGAGAGAAACATCTAGAAACAGTTGCCACAAGTGGAGGCCATCTAGGTCCAGGGTTAGGAGTTGTAGAGCTGACATTAGGTCTCTACCAAACTCTCAATCTAGATCGGGACAAAGTTATTTGGGATGTAGGCCATCAAGCTTATCCTCATAAAATTATCACAGGTCGATATCACAATTTCCATACTTTGCGACAAAAAGATGGTATTGCAGGTTATTTAAAACGATGTGAAAGTAAATTCGACCATTTTGGTGCTGGTCATGCCTCTACAAGTATCTCTGCTGGTTTGGGGATGGCCTTAGCCAGAGATATGAAAGGAGATAACTTTAAAGTAGTTTCCATTATTGGGGATGGTGCTTTAACTGGTGGTATGGCTTTAGAAGCCATTAACCATGCAGGTCACTTACCCAAAACTAACATACTAGTTGTGTTAAACGATAACGAGATGTCCATTTCTCCTAACGTAGGTGCAATTTCTCGCTATCTCAACAAAATGCGCTTATCCCCACCGATACAGTTTCTTCAGGATAACTTAGAAGAACAATTCAAACAGATTCCTTTTGTTGGTGAAACCTTTACACCAGAAATGGAAGGCCTCAAAGGAGGAATGAAGCGTTTAGCAGTGTCAAAAGTGGGGGCTGTAATTGAAGAATTGGGCTTTACCTATATGGGTCCTGTTGATGGGCATAATTTAGAAGAATTAATTACAACTTTCAACCAAGCTCATCAAATTCCCGGACCAGTATTAGTTCATGTTGCCACAACTAAGGGTAAAGGATACCCAGTTGCTGAAGAGGATAAAGTTAGTTATCATGCTCAAAATCCCTTTAATTTGGCCACGGGTAAAGCTTTACCAGCAAGTAAGCCAAAGCCTCCTAAATACTCTAAAGTTTTTGCCCATACTTTGGTGAAACTTGCGGAAAATAACCCCAAAATTATTGGTATTACTGCTGCTATGGCAACTGGCACAGGTTTAGATAAACTTCATGGGAAACTGCCAAAACAATATATAGATGTTGGTATTGCAGAACAACATGCTGTGACTTTGGCAGCAGGTTTAGCTTCTGAAGGAATGCGACCAGTGGTTTGTATTTATTCAACTTTCTTGCAACGAGCTTATGACCAAATTATCCATGATGTCTGTATTCAAAAGTTACCTGTATTCTTCTGTTTAGACCGTGCTGGTATTGTAGGTGCAGATGGTCCGACTCACCAGGGAATGTATGATATTGCTTATTTACGTTGTATCCCAAATATGGTAGTTATGGCGCCTAAGGATGAGGGTGAGTTACAACGGATGGTGTTGACTGGTATTAAACATACGGATGGGGCGATCGCTATGCGTTATCCTCGTGGTAATGGTTATGGTGTGCCTCTGATGGAAGAGGGTTGGGAAGCTATTACTATTGGTAAGGGTGAGATTCTGCGGAATGGTGATGATGTGCTGATATTAGGTTATGGGTCTATGGTCTATTCGGCTATGCAAACAGCAGAAATTCTCAGCGAGCATGGTGTTGCTGCTACTGTCGTAAATGCTCGTTTTGTCAAGCCTTTGGATACAGAATTAATTCTACCTTTGGCACAACGCATTGGTCAGGTTGTGACTATGGAGGAAGGTTGTTTGATGGGTGGTTTTGGTTCGGCAGTTACGGAAGCATTGATGGATAATAATGTACTTGTACCTGTTTTACGTTTGGGTGTACCTGATAAGTTGGTGGATCATGCTAAACCTGATGAGTCGAAGGCTGATTTGGGTTTGACTCCTTCTCAAATGGCAGAACGTATTTTGCAGAGTTTTAAGCCTAGGTTATCGACTATTAATGTTTAATAGAGTTGTTGGAAGTCTTAAATAGACTTCTGGTAAAAAGTTAATCTAGGGAGGTTCCATGTTTATTTGGGTATTGGTAAAATGAAGGAATGAATTAAGCTTGAATGGGCACTTCTCCAAATTTGAGAAGCGTGATATCAATAGACCAATAGAATATTTGAGTATATCAATGCATTTTGAATAACACAAGGTTTTGCGATGGAAGCGACCTTGGGGTCGTGTAAGTGGGTGTTTTCCCCTTAGAAGTTGCTCATAGAGGTCCTACTTACAATCTTTTCTCCATTAGGTATCAAGCCTGGATAAACATGAGTGCCATAAGTAACCCAAAAGCAACACTGCCAACAAACGTTAGCAAAGCTTAACCTCATCAATAGCCTGCCATAGCGGTTGAAAAGTATCAGCACTGTGGTGTCCCATTATCCAACTCAGAATTCCTGGACGGAAATGGTTTAGCAAGGTCTAGAACCACACCTTGTTTTTCTTACAACCAACAAAGGTTGCGAGTTCATTAAGTTTTTCCACTTGGGTTAGTTTATCTGGGTCATAGCTATCAGATAAGCGTTCCCCAGTGTGTTTTATCTAATTGATCAGGCGTTAAATTTGTCGTCCCTCTCACTCTGGCAATTTCTCTAATACCCATACCGTTGACATACATTCTCAGATATAGCCACTTGATATCATCGCTGTATCTTCGTGGTTGAACTGGCTTGATGAACTGACGAGTACAAGCGACGCACATAAGGTTCTAGTTGCCCCATTGATAGCCCTTGTTTTCGGATGTGCTGGCTGCTATATTTAGCATATTTATGGGCTTATCTCTCATAATGGTTAGTGACGTTAACTATCATGAAGCAACAATAGATTCATTCTGCTATCTACCAACCTCTCTTATCTGTATTAACTAGTTAAGTAGGAAAAACTAAATTTATGTAAAAGGAGAAATAATGGACAATTAGATACACCGCAACTATCGCTAAATTAAAGTGTATCAGATCACAGGTTCAATTGACGCTGAGAGCCAAGAAGTGAATCTTGCAAAAATTTGGGAAACTGAAGTTGTTGAGGATATTCGCCCTACCTTTCTGGAACACTTAGCAATCTTTTCTATTAATTAATAACTCACACCTCACCAATAGCTTGCCTTTGCCAAGCAGGTTGTTGATATAATGGAATACCAACTGCTTGAATAATTGCCTGAATGTTCGCAGATCACACCGGTGCTAAAGTTGGAGCATGAGCGGGCAAACTTTGGATATCTGGGGTATTCTGATACCATATATCTAGAGTATCCGCCAATGGGGAGTATCCTCTAGGCTGTTAATCAGGGTTAAGATAAAGACACGATATATAGTGCATGGTAATTTAGTAACCTTCACGCTCTGGGAGTCATTAGGCCCGGCGCTCCTATACACTCCATGCGATCGCTGAACTATTTTTATGAGAGTCATCGCGAAATAGAGGAAAAAAATCGCTCCAACCTAGACAAAACAATAATTTAAAGTTTTTTTTGCTTGCCAATAGCCACAATCTTTACACAACAAAGTTTTTGGTAATTTTTTAAGTTATCAAGGGACAAGTATATTATATAAAATCCGGTTATATAGTTAATGTATATAGATTTCGGAACTTCTGGTGGAGATGATTTGATTTATGTTAATGATGATTATTATTGGAAGAATAAAACTAAAAAAACAGATTTAAAAAACAGGATTTGGATATTATTTGGGAGACTTGTTAGAGGTAGGGGAAAGACTAAAGAAAAAACCTATTATATAAGGCCAATACTAAATTTATTGAAGTAACTTACAATATATTATATCACTTTATCACTGATTATCCAAGGGAAGCAAGTAAAATTAATGAACGCTTTATAGAAAATATCCATCAACCCTCTAAAACCAAATTCATAAGAGGATTTAGCTTAATTTTAGATGATACTGGTCATTGCAAAATTTTAAATTCATATCTGAGATTCTATCCGGAAAATAGCACCAATAGCTTGAGACATTAGGAAACTTCCATGATTTCCTAGTAGGAGCTATGCCACCAAAAGCTTATTTGAAACAGTACCTAACTATAGAAGAACTGAAAATTCGCTACCGACAAGCTCCAGACACCATTGAATCCCGTCGGTGGCATCTCCTGCTTCTAATTGCCCAAAAATGGTCTATTAAAAAGGCAGCTCAAGTTGTTGGACTTAATTATGATTATGCTAAAGAAATTTTTGGTCGGTACAACCGAGAAGGACCAGAGTCTGTAAAGAATCGTAGCAAAAATCGTCAACCACCACCTGCTAAATCTTTATTGACTCCTGAGCAACAACAGGAACTATTAGTAGCCTTACAAGGGCCAGCTCCTGATGGCGGGCTATGGTCTGGTCCAAAAGTAGCTCATTGGATAGCAAAGAAAACTGGTCGATCTCACGTTTGGCCTCAACGAGGTTGGGATTATCTTAAAAAGTTGGGTATTGACTGGAAAAAAAAATATCACAATGATTGATAATTCTTGATTAGATTTGGTCTTTAGTCTTTGGGAAACTTATTTTGTACGGAGCCTTCAGATTTCTGTCTGATACCAACTTTTTTTTATATAGACCTGGCCACAGTTATTGGGAAGCAGATCAGGAAGTGTAAGAAAGAAAAAAGGGAAAAAAGATTTAATTGTACTTTGACCAGATATCTGCAATGTTCTAAATACTTTTCCGGAGTCATCGTAAAAATCTTGATAAATTTGAATGAAGGTTGTCAAAACTATCAGTAATGAATAATTATCAATTATTTGTTTGGCAAAATCTGACATAGAAATATACCAAGATTTAGTGGTTATGAAAATTAATACTTCTACAAAAATAATTGTATTATTTGCATTATGTTTGGGAATTAACTTAAGTATCAATAATACCGCTGATGCTAGACCAAAAAATAGGTTAATTTGTCAAATAAGAGCAGAATTATGCTCAAAAAAAGAAAGTAATCTTTTATGTACAAAAGATGACAGTTGTTCTCAGAAAAAAGTAGAAAGTTGTGAGCAAGATAATCAGATATCCTGCGATAAAACACAGTCTACAATTCAGGAATTTAAACCTGTAATTCGACCTAATAAATTTTCTTGTGATGAAGGTGAAAGTGGTATTCCAACTACTTTTGTCAAAACACCACAAGGTGCTTATCCTGTGATTCGCTGGGTTTCTAATTATTTCTTATCTGCTGGATATAGTCCCATGACTCGTTGTCGTCAAGTATCAAACAAATTTCAATTATTTTATGATGATGGCAGACTAGATTATATTACTACTGGCATTGTTAACCGTCAACCTGTTGTCTGTATTTCTAGTCACAAGGGTGGTCCCTGTCAAGGGGTTTTATTTACTCTCAAACCTAATCAAAATGCTAGCAAAACAATTCAAAAATTATTTGATATTCGGGTTGGTGCTACCACAGGTCCACTATATGAAAGTAGTTCCCGTTTCTATTTAAACTTTAATGATTATTTAGAAAGTTTAGCAAACAAGGGTATGGAGTAATATTTTGTGAGTTTGCGATGGTTGATATTAGCAGTTTGTATTGGTAGTGAGTTATTTTATTTTTCAATACAAACGTTACCTAAAAAATTGCCTGACTTGGAAAGTTCAGCAACTCAAATACAAAGTAAAAATTGTACTAACTGTAATAATTTTTGTACCATTAAAGAGCTTAAAAGTTTAGCTAAATCAATCACCGTTAAAATTATTTCGGAAAATGGTTGGGGTTCAGGAATTATATTGAAACGAGAGAAAAAAGTTTATACAATTGTTACTAATCAGCACGTTTTAGATACTAACTATAAATCTTATCTGATTCAGACTCCAGATGGTCTTTTTTATCAAGCAAATCAAATAGAAAATGAAGGCTTTCAAGGAAATGATTTAGCTCTATTAAAGTTTCGTAGTACTAACTCCAACTATACTGTTGCATCTCTCGAAAATTCTGCTACCCTTTCTCCAGGAGATAAAACTTTTGCTGCCGGGTTTTCTGCTTTAGAAAAAACTCAATACATAGAACTTTTATTCACTAGAGGAAAAATTTCAATTTTGTCTGACCGCCCCTTAGAAAAGGGTTATCAAATTGGCTACACTAATTTGATAAAAAAGGGCATGAGTGGGGGTCCTTTACTGAATATTTACGGGCAAGTAGTTGGTATTAATGGAATGCACGCTTATCCTTTATGGGGAGATCCTTATGTATATCGTGATGGTTCCCAACCAACTGAAAGTTTACGTCAACAAATGAGTCATTTAGCATTTGCTATTCCTATTGAAACTGTAGCTAAATTAGCTCCAAATTTGCATCTATACAAATTATTAAGCTCCAGAAAATTTTTACTAGCAAGAAAAAGGCAAAAATAAAGAAGGGAAATAGATAACTCTATATAGTAATTGGCTTATAGTTTGTAATATTTTATAATTACGGAGTTTGTTCCCTTAACCTAAACAAATATAGTATAAAAAGACTAAACCCCTACAGTTTTTTTTATAAATTATTTAATGCTACTTATAGATTAATAAAGTTCACTTAAAGATTTTTTTTTAGGAATTAGTGTCGAAAGAGAATTAAAAAGTTATGTTTGCACATCATGACCTTTGCTCCCCATTCCATATGTTAGGAATGTTTTTGTTAAGAGAGGAAAATGTTAGGAATGTTATGTAATTGCTCATGAGGTAACTTTAGTATTTTATAGATTCAAAAGCTAAGAGCTAACTGCTAATAACTGAATGCTTACACATAATCGTTTCATAAATTATGAGCTTAGGTATTATATCGACCGTATTAATTTGCAGTTTTTTTATATTTATGCTCAAAATTTATCTCTTGTAAAAATATTAAAACACTAGAAATATTTAAGTAATTTTGCAAAATTAATTAAGTATATTTAATAATTAATTTTTAGTATAAAAAAACAAGAAATGTTTATATAATTATGATATTTATTAGAGACTTAATACTATGGAATAGAAAGCTTTTATAAAGTATGATTATCATAGTAATTTTAGTTAATTTAGGGATACAGCTAAATGTATAATATTCAGCAGTTAATAATTTACTATTAAATAATTTAGACAATGTTTAAGTCAGTAATAAATCGTTCTTATTTAATCTTTTCATGTCAATATCTAGCAATATTAGGACTATATCATCAAAGATTAAGATACAAAAAATAAAAATAAAAATCATAAAAAAAATTAAATGTTAGTTTTTTTTTTAATTAAAAGCACTAAATAAAATTAAAATTCAAACAAAAAAAATGGGGATTTAATATTAAAAAATATTCAATAAAATTAATTATAAAAAGTTAATCATGAGATTGAATGTATCAAAATTTAAATAAGTAAAAGCTCTAATAAATCATAGCTATAAGTAAAAAAAATGAGGCTATAAGCACTCCAAATTAAAGATAAAAAAGATAAATTGATTCAATTTAATTTTTTATAGGAAATTAGATTTGCTTTACTATATTTTTCTTATTTATTGCGTAAAAATGTATAAAAAAACTAGTAAAAACCGTAAAATTAAAGTAGTAATTTTTATTGGCAAATTAATTTACAGCTAATTATTTGATGTCTATATTAAATGTCAATATGAAGATTAAAGTAGTGTTATTTATTGAAAAAAACATTCATAAATTGTCTCATTAAGCCGTAGTTATTTTTGAGCAAGCGTCGATTCATACTAATAAAAATTTACTAAATAAATTTGAATAATAAAACTAAAAAAAATATAGAAATATGTGGGTTAACTGCCTATTCACTAAAAGCAAACAGAAGAGAAATATAATATAGAAATATTATGCAAATTTACTAAATCTAAATGGATTAAAGTAGAGTTAATTGATAACTGAAATAGCTTACTTTATAGTCCTGATAGAAGGTATACAAAGAATAAAACACACAGGATAAAAATACTCCCAGTGCTCTTAAGAGCAAATATTAGCGGACAATTCACGACAATTATAATGCACCACTAACCTTACTTCAATATTTCAAAAAAGTGCTTAGTAAAGCACGGAACAAAATATGTAATTAATTTAGCTTATACATTTATATTTATTCAAATAAAAATATGAGATTTCAAAAAAAATTATGGGATTTAATATTTTTTTTATTCCCAATTAAACAATTACTTATTAGTTTTTCCTTATTACTTATTTCTCCTACATTAATATTTTTCAAACAACCTGCTGCTATAGCCTTAATGGCGGATAAAATTAACCAAATCTCTACAGAATTTACAGTATTAATTGATGCTATAAATCCTGCTTCTGGAGTAATTATTTCTAGAAAAAAAGACACTTATTATGTTTTAACTGCGAACCACGTCGTCGAAACTCAAGATGAATATGCAATTTTTACCAAGGATGGAGAAAGATATGAAGTTGATTATCAAAAAATAATTAAATTGCCAGGAGTTGATTTAGCAGTTGTAGAGTTTCGGAGTAGTAAAAATTATCAAGTTGCTACTTTAGCTGATTATAATTATCAAGCAGAATTTCGTCATGTTTTTGTGTCTGGTTGGCCTGATTCAAGATTACCTTTTGATGAAAAAGAACATTTATTTAGTCCGGGATTATTAATTAATAAAGATTATGAATTAGCCTTTATTAAGGATCCTATTTCTAATGGTTATGAACTGTTTTATAATAATATTACTAAGGTAGGTTTGAGTGGTGCACCTGTTTTAGATACTCAAGGAAGAGTGATTGGAATTCATGGTGCCTCTGAAGGTACAAAAATTTATGATGAAGAGTCTAATTCAGTGGAAAGGGTGAGTATTGGTTTTAGCTATGGTATTCCTATTAATATTTTTTTGAAATTGGCAGATAAGTTAAATATGGGATTAAATTTTCAATTGGAATATTCATCGCCACCACCACTAACTCAAAAAGAAGCTTTTTCTATAGAAGCTTATTTAAAAGTTCCAGAAACAAGAGATATTTCTAGTGCAGTAGCATGGGCAAATCATGGGAATTATTTATATCGTTTAGATAAATTTGAAGAAGCATTAGTAGCTTTTGAACGCTCAATAAAAATCAGGAAAAATTTCTATCCAGCTTGGTATGGGAAGGCAAATGTATTGTCTGCTTTAGGTAGGTATGATACAGCAATAGATTGTTATAAAAAGACAGTAAAAATCAAACCAGACTTTTATTTAGCTTGGCGAGATAAAGGAGCTTTATTTGCTTATTTAAATCGACATTATGAGGCATTAATATCTTTTAATCAAGTAATTAGATATAAGCCAAATGATTTTGCTGTTTGGTATCTGAGAGGTAATATTTTAACAACACATTTTCAGGAATATAAAGAAGCGATCGCTGCCTATAACAGGGCAATTGAATTAAAGCCTAATTTTGCTTATGCTTGGATAGGAAAAGGGGAAGCTTTTTATCGTTTAGGAAACTATGAAAAAGCTAGAGAGGTTGCTCAAAAAGCAGTAAAACTTAAGCCTAATGATCCAGAATTTTTGACTTTTTTAAATATTCTGGAGAAACATAGTTTACCATCGGCTCCTATTAAGCCGATACCAAATAAAGGAAAGGTTGAAATAATAAATTATCCTTCTCGTAAACAACCTAACTTATTGTGGTAATTAACATATAAATGAATAGGAAATAGGAAATCACAAATGGTAAGTATTCAATTATTAACATTTTAGTAATGGAGTGACACGTCTAAAAATATAAGGCCTATAAGAAGGAAATAAAATCCAACAATGATAAAAGTAGGTTGGATTTTGTTCTAAGACTCAACAAAGCCTTATTTTACTATTTTAGTTTGTCGCTCCAGTCGTTATATTATTGAACATAAAAAAACATTATACTGTATTTTTTATTAGTTAAAATTAACGGGAACATCTAGACCATAAATGTCGGCATATTCTACAGATTAACCCCACAAAAATCGGGAATGTTATGACAAGTTTTTTGGAGCTCATTTGATTGTTGAATTAAGCATTCAGCTATTGATAGTCAGCTTTCGGCTGTTTAATTAATGGCATTAGTCGTAAAACTGAGTTATCTATCCGGATTTATTAAAATAGTTCAGAATATTAAAGTATAACTAGTAAACAAAATTTTTCTTAACTTGACACAACAAACAAAAATGTTTTCCTCAATATTAAAGATTGTTAACTACACAGCAGAATCAGAGCAGAGAATATTTTTTAACAAAATATTAACCTAGGAATTAATAGGATTAATTTATCTCAATTGCTAAGAGCAAAGGTAAGGTATTTATATCTGTACTTATAAATAAAATAATAGCTATACTTTAGTTAATATTTTAGGGGTATTTTCTGCTAATTAATAATTGTGTTTTCTTGCCATATCTTACTTATTATTTCCCATCTTATTTTTGATATTTTGTAATACATTTAATATCGACAATTCAAAAATATTAGTTTTTATATAGCAAAAGGAGTAATATATGACGATATCCAGATCATCTCAGTTGAATTCTACAAGTAATATTCATAATCTAAGTAACCCTGGTCAAATTAGTGGTGCTAAATTTAATGATATTAATTTCAATGCAATATTAGACCCTGGAGAATTAGGTTTACGAGATATTACTTTATACTTAGACCTGAATCAAAATAAATTTTTAGATGAGGGAGAACCTGCCACTATTACTGGTGTTAATGGTGAATATTCTTTCCGAAATTTACCTCCTAATACTTATATATTGCGAGAAATTTCTCCAATAGGTTTTGCTTCAACTACTCCCGACCCAATTTTAAATGTAATTCCAGGAAGTAATCTAATAGTAAATGTTGGGAATGTAAGCAACCGTGGTCAAATTAGCGGTGCTAAATTTAATGATATTAATTCCAATGGAAAATTTGACTCTGGAGAATTTGGTTTACAAGATATTACTTTATATTTAGACCTAAATCAAAATCAATTCTTAGACAACGGAGAACCTGTCACTATTACTGATGTTAATGGTGAATATTCTTTCCAAAATTTACCTCCTAATACTTATATATTGCGAGAAATTTCTCCAACAGGTTTTACCCCAACTACTCCCGACCCAATTTTAAATTTAACCCCTAACAGTAATCTAATAGCTAATATTGGGAGTGTAAGTAACCGTGGTCAAATTAGTGGTACTAAATTTAATGATATTAATTCCAATGGAAAATTTGACCCTGGAGAATTTGGTTTACAAGATATTACTTTATATTTAGACCTAAATCAAAATGGATTTTTGGATGAGAGAGAACCTGCCACTATTACTGGTGTTAATGGTGAATATTCTTTTCAAGATCTACCGCCTAATACTTATATATTACGAGACATTTCTCCAACAAATTTTATTTCAACTACTCCCAAATCAATTTTAAATGTAACTCCGGGAAGTAATTTAATAGCTAATATTGGGAGTGTAAATAACCAAGGTAGCATTAGTGGCATTAAATTTAATGATACGAATACTAATGGAATATTTGACCCTGGAGAATTAGGTTTACAAAATATTACTCTATATTTAGATCTGAATAAAAATGGATTATTAGATGGGGAAGAACCTTCCACTATGACTAATGTTAATGGTGAATATTCTTTCCAAAATTTACCTGTTAATACCTATATAATTAGGGAAAATCAAGTATCAGATTTTATCCAAACTACTCCCGACCCTATTATTAATGTTACTCCAGGAAGTAACATTAGAAATATCAATATTGGTAATGTAAATAATCGAGGTAAAATTAGTGGTACGAAATTTAATGACACAAATACTAATGGAATGTTTGACCCTGGAGAATTAGGTTTAGCAGATATTGCTTTATATTTAGACCTAAATCAAAATGGATTCTTGGATGAGGAAGAACCTTCTACTATTACTGATGTTAATGGTGAATATTCTTTCCAAGATTTACCTTCTAATACTTATATTTTGAGAGAAATTTCTCCTCCAGGTTTTGCTAAAACTACTCCCGAACCTGTCGTGAATGTCACTCCAGGTAGTAACATTACAAATATTAATATTGGTAATGTAAATAATCGAGGTGAAATTAGTGGTACGAAATTTAATGATACGAATACTAATGGAATATTGGACCCTGGAGAATCAGGTTTAGCCAATATTACTTTATATTTAGACCTGAATAAAAATGAATTATTGGATGAGGGAGAACCTCAGACTATTACTGATGTTAATGGTGAATATTCTTTCCAAGATTTACCGCCAAATACTTATATAATTAGGGACGATCAAGTGATAGATCTTGACCAAACTACTCCCGACCCAATTGTTAATATTACTCCAGGAAGTAACATTAGAAATATCAATATTGGGAATGTAAGTAATCGAGGTGAAATTAATGGCATTAAATTTAATGATAAAAATACAGATGGGATATTAAACCCTGGAGAAAATGGTTTAGGTAACTTTACCTTATATCTAGATTTGAATGACAATAGTCTCTTAGATTTTGGGGAACCTGCAACTATAACTGATGAATTTGGCTTCTATTCATTTAAAGATTTACCTCCCAATGTTTATATAATACGAGAAGTGCAAAAAATTGGTTTCTCTCAAACTACTACTGATCCAGTTGTTAATGTAACTCCTGGCAGTAATATTAATGATATTAATATTGGCAACTTTAATGAATTTATTTAAAATAGTTTGACAACATAAAGTTCGATATAAATCCTAAATAATTTTAGATAAAGTTCTATGATACTGCATTTATATTTAAAATTATTTAGTACTAGTATATGTTATAATAATACCATAGTATTTCTAAAGATTAACTATGGTATTATTGTATTATAATAGTACTATAAAATGAATTAGTATTAGTACTATTCTTTATCTATTTGACGAAATAATATTACTATGAAAGCTTATGTTAATCTAGAGATAGATTTTACAGGAAAAGATTATTTTTTATTTGAAATAACTCGCTAATCTCATAAAAAAAATGTGGTTTATCTGTAGAAATTGAAAAAAACATAGCCTCAATTTAGGGTAAAAGATAGTGGTTTAGTGATAGGTTAAAATATTGTTTCATTAGCTCTAACTGCTATGCAAATTTTTTTGTCTACTTTACAGTTTGGGGAATAAAGTAAAGACAACAAGGTAGTGCCTCAGTAAAGTGTGGGATAAGTAATTAAGTCGTTCCCACTCCAAGGAGCGATCGCGTTCCTCAGCTCTTTGCCTAGCAGTATTTTCTTTGGGACTATGAACCCAAATCAAATAAAGTAGGCCCTCGCCAACCTTACTGTTACCTCAGTTTGTTGCCAGAGCTTGCCAAATTTATTCTCTCGGCGATGCCATCGACCGAGCTGCTGTCTGATAATTCCATTTGTGCCTTCCAATTACAGGGCAATGGTTTTTACCAATAATGTGTTCTATTACAGGGCAATACTCGTTCATACCCTCCAATCATCAGTTAGCCATTTTTTACAGCTAGTTTTCCCTTCTGTGTTGACGACCAATTCCTCAATGAACTGGTCAGTATGTTTACTTACTCTAGCACTCAGAATTAATCTACTGGATGAAGCCTAGGGGCTTGCCAACCCAAGAATTCCCTTCTCTCAATTCCTGATACTGGCACTGTTTTTGTTTTTTTGGATGAGTGACCAAAACTCATCACTGTTGATTTGTGAGGTATTGATATTCTGGAGATGAGCATTATGAATCTATTTGTTCTTTTTCAGAGGGAGCTCTCACCAAACTAACTATCGTATTATCGGCCAAATTCACTGTTCGACTAATCCCTCTTAAACTACTGCCCTCAACGTGAGCCTCTAGAACCATTCGTATTTGTTCAGGTTGAATTGTTCTACAATAGTAGAGAGTGTCAAAAGTATCGGTAAAAGTTTGTAGGCATTCAGGACAATAATATTGTTGACAACATTACTGGTCTTTCCATTTTTATGAGTTTTCTGATGGGGACATAGAGTACATTATAGAAAGTATTTAAGGACAACGATTATATTACCATTCCCAAAATTTCTTGATGCACTAACCGTAATTCTTATAAATTAGATTTGTGTATGGGTAATGGCAATCAGATAGAGTTATTTTCATTTCCTAACTAACCAAGAAGATTGACTCAGCCATAAGCTTGTGGTCTAATAAATTTAGATTTAGAAGTAGATAATATTGATGAGTCTGTTGATTATTTTAAATATCACGGTATAGAAGTAGAAAATATTAGAACTGACGAAATAACTGGCAAATGTTTTACTTTCTTTCTAGATCCAGATAAATTACCCTTAGCAATTTATAAAATTTAATATTTTAATTAGTAGTTTGATGATTATTATTTAAAGTAAAGGTAGTAAATAGGAAGTAGCTAAGACTAAAATTGAGATAGTTTTTTGAGTAGTTTTATTTCCTACTTATTCATCTTTTGTTCTGTCGATAATTTTTGCCCAATTCGAGGTTCTTTACAAGCTAAAAGTCGTTCAATATTGCTAATGTGACGCCAAATCACATATATACCACCAGTAATAGCAAATATCTGATAAGGAAGTGGTTGACCTGTGAAAAACATCAAACCAGAAACAGAAATAGCAGCTATAATAGAACTCAAAGAAACAATACGACTAATAGTAAGAACAACAATAAATACAGAAAGTGTTCCTAAACCAACAACCCAAGAGATTGCTAATAAAATACCCAGACTAGAAGCAACAGACTTGCCTCCTTTAAAACCAATCCAAATAGATTTAGTATGACCTACTATAGCAATTAATCCGGCTATTATAACCATCCATTCTTTTGCTGTATCAATATCAGTTACTCCAGCAATAATAGTTAGGTTTTGAGCAAACACCAGAGAGTAAATATAGCGAACCAAAGCGATCGCTAATGCACCCTTAAAAATATCAATAACCAATACAACTAAAGCAGGCACATTTCCCAAAGTTCTTAATACATTAGTTGCGCCTGTGGAACCAGAACCCTGTTCACGAATGTCAACACCATAAAACCAAGAACCTATCCAATAACCACTAGGAGTAGCACCCAATAGATAGGCAACAATTAATATTACTGCATTTAGTACTAACCAATTAATCATTAACTTATTCCTTTAAAAAATTAGCATGGCGCTACGCACCAGTCAAAAGTCATGTATTCAAAAATAATTAATGAAGTGAGTTTTTCGGACTTTAAATGATCCGGAAATATGATTTATCAATGTCCCTACTCTACATAGGTAGTGCTATAATAGAAGCAATCAATGTTAGATATTTTTGGATAAATCTTTCCTCAATTAATGACATAGTTAAAAAATAAATTATAATTTTTCAATATGCAACACTTTTTGGTGTTAGTAATTTCAAAAATTAACCAGGCATTGGTAATAAAGAGAATAATTTATTTCATGTCTGCCCACTTTTTCCTTTTTTCTTCTTCAATAAAATTTATCGGTTGAGTTTTGAGAATTAAGCTCAGGAGCAAAGGCCAACCATAGAGGAAACTGTAACATAGAAAGACTAATTTTATCTTCCGTATCATCAATCACAATTATTGGTAACTTGCCCTGCCTCACCAACCGATCTGCTTTTTGGGCCAATACTTCCGATTCCTCAAACAAAGCCACACCTCTCTCTGGGCTAAAATCACGGCGGTCAATTCCCAGACAATCTTGTAAACCACGACGCCATTCTCCCAAACGCTCAGGAGAATTAGCAAGTATCAGAGGACGTAGCCTTGTATCATACAAATCTCTGAGTATAGAAACAATTGCCGAAGCCACCAAAATATTTTGTAAGCGACTACCCATAGTTCGGAGGGAACCACGACCACCTTGAGAGAAAAACCAATTTGAGACTCTTTCTGCATGAATAGGCTCAAATGTACGCCGTAATTTCCAAGGGAGACCATAATAATCAGGCATCTTCCTATATTCCTCCATAATCTGGCGAATCTGTCTAGTTTGTTCCTCAAAACCCATTTCAGCAAATTTAGGATTTTCATAATTGTTGACAGATATAGGAACATCTTCCACTATAGGAGTAGGATACTCCTCTTTTTGTGGAGTTAACTCTAACTGTTCGGCAGCAGCAGCCAAATCTTGCAAGCTTCCCACCAAATAATCTTTAAAACCCTTAATTCTAATTGCCAAATCCTGAGAAGTGCCAGCAAAAGTAGTCCGCATCTCCTTTTCAATACGTTCTTTGCGATGCTCTAGTTTTTCTACCTCTATTTGCAAGGTTTGTTTATGTTGCTCCAACTGACTTAAAGCTTCTGGGACTAAACTCCCTATAGCCTTAGTTTGGGCTATCACTTCTTGTTGTAATTTAGCCTTAATTTCTTGTAAAGTAGCTATTTCTTCTTTCAAGTTTTGTTGTTGCTGTAGTCGATCAATAACTACTGTTGTTAATTCTTTTTCATTTTTATCAACTGGCGCGGTTGTAGAGTCCTCAGTCAAACTAGAAGAATCTGTAGAAAGAGTTTCAATCTTGATTTTTTCATCTAAGTCGGTAGCTTCAGGAATTATTTGATTTAAGTTATCTGAATTCACTGAAGTTTTTGTTAATGGTTCTTTTGGTTCTTTTGGTTGTATTTTGTCTGGGTACATCATGAAAAAAAATATAAAAAATTTATACTATTGAAAAAGAAAAAATTCCCATAGCTAGACTAAAAAAGCTGTAGTAATTTATGAAGTGGAAATAACACAGAAAAACTTTTGTTTTTCCAATCTCAAACTTTACATATTCTAGCTAGTGCAGTTTGTGACAAATAAAATAACTGATAAATTACAAAATTATTAAAGTAATACTCATCAACAATACTTTTTAATTTTGATTTCTGGGTAGCGGCATCAGTTAATCCTGATTTAAAGGAAAGTTATTTTCTAGGCAAGTTCGCAACATTTTAGGATCAAAAATAATTGGTAGAAAATGGATACTTTTAATTTCCCTAAAATAGAATAGAATGGGAATAGGAGACCAGAATATTTCCCAGTTGAGCCAATCTTGATAAGGAAAGTTTCGTAAGAGTTTCTCTGAACGGTATACTTCTAAGGCTGTCTCAGTAAATTTCAGACGGATAGTTATTGTTTGAATTAATAGAAAAAGTCCCAATATAGCGATCGCTATACTCACCCATTTTTGTATAAATGCCAAAGGTAATGCAGCAATTATTAGGACTAAAGGAATTTTATAACTAGGGGCAAGTTCAATAGCTTGTTTTGCTTGTGAGGTAGAAATAGTAGTCATAGTTTTATGTTAATTAATTCAATATAATTATCTATTTTTATTTTCTGTTTCTTGTTATCTACAAAAATCAGTCAAACATAATATTTGAGTGATTAGTTATTTCTATTCGGTGCTTCAACTGGAAGTATATGCAATCTTTATTCTACAAGCATACGAGGTCGAACTGAGGTGACATTGCTAAGTTGTTGACTGCATTCAAACCTCATTTCACAACTAAAACTACACTAAAAGTATTTCAGCTAACATAACTTTTTGCTCTTTATTTGGGTGCAATTTATTTTTTAATCCAAGTATTATAAAGCAGATAATTGGTTATTGTTATATTATAGATAATATCAGATTACAGCAAATACTTACAAAGCCTAATTTTTAAAACTTCAAAAACTACAATTGCAATTACTTTTTTGGTAATGAATCTTACCACCCTCTTAAAAAAAGTTTTTTTATCTATGTTTTATCTATTTTTATCTCTTTATTATGCTTTATTTTACCCAAAAACTGTTTCGGCGGTTGGTTTTATTAGTTGAATCTATGCTTTAGCTAATAAATGATAATAAAAAAATGATTATAATTTTTTTTATTCAATCAAAAGTCAATTATGGTCCAATTTTTTTTTTCAGAAGCCCGTAGCAAAAGCACAGAGTATTATATAGTATATTCCAGATTAATATAGTTCAATTGACAGAATAAAATTTTTTTCCTATTCTACCCAACCCTAGTTCAAAGGCCCTGCTTCATGGCCCCACCCATACCTTGGAACATTGCCCAAGATAAAAAGAAATTAAAAATAAAGATAGATATTAAGGATGTCACAACGGCCGTAGTTGTAGATTTTCCCACACCTTTTGCCCCACCAGTAGTAGTTAAACCCCAGCTTGTACCAATTACAGCAATTAAAACACCAAAGACAACTGATTTAGTTAATCCACTGCACAGATCCCAAAGAGTTAAAAAACTCCGGACAGAATCAATATACATGCTTTGGGGAATATCGTATAGATTTACTGCAATTATTAGTCCACCAAATATAGCAGCCACCAAACACAATAAAGTTAAGATTGGCATCATTACACCACAAGCAATAACTCTGGGAATAACTAAATAATCTACTGGATCTGTTTTCAGTATATATAGAGCATCTATTTGCTCTGTCACTTTCATCGTGCCTATTTCTGCCGCAAATGCTGAACCTACTCGCCCCGCAACAACAACTGCTGTTAAAACAGGACCAAGTTCCCTAGATAAAGTTAGAGCCAACATACCTCCAACCATATTAGCTGTACCAAAAGCTACAAGTTCCCTGGCAACCTGAATAGTAAATACCATACCGACAAAACTAGCTGTCAGCAAGACAATTAGTAAAGATTCTGGACCGACGATCGCCATTTGCTCAATGGTATTACGACGATAAATTTTGCCATGGAATAAATGGACAAATACTTGGCCAGCTAAATATGTAGCTGCCAACATTCGTTGTCCCCACAACCCTAAACTAAAGTTAAAAAAAATTTTACTCAATATAAACTAGAATATTTACGAGAAATTTACTAATCTTCAACAAGATTTTTAGATCAAAATTTAAGTTTTCTTACAGATTTACTGATTTTAAGTGATATTTATCTATAATAAGCGAATTAGCTTATGTAGTTAACTTGCTACTGAAGTTGAATTACATCTGAACTTGTGGTTAATTATTATGACTATTTTAACTAATTTCCTACGTTCTTTACTATTAACAACTATTTTTAGCTTTATCACTCCCATTATTTTAATTGGGGTTAGCTGGGTTAGCTTTACTTTAATTAGTCGTCTTCCTAGTTTACAGGGAATTGGTCAATCTGGTATTGACCAAATGTGGGAATTATTAGCAACTTTCGGCAGTGGCCATCCTTGGCAAGGATGTTTAGTAATTGCTATTACCTGTAGTTTAGTAGGAGCTATGTTTGATACTTATGTGTTTTATCAAAATTCACCGAAAAAATGGGTCTAAAGTCTCTATCTTTTAGTTTGACCTTTTATGGATTAAAGTAGTAATGAATATATTATCATATGATTAATTTAGATAATAATTATGAAAGCTTAATTTAAGTTTAGTATTTATCCGAATCTTGTACAAAGACATCGACGTTGCAAAGCTATTTGTTGGTGTACTTGTTATTTGGAATGATACTCTGGCTTGCTGCCAATAAAATTATCAAATAGGAGCAAATAAACCATTATTATCTAAGCTACTCAACTATTTTCTTTAAGTGCCTAAATAAAGTTAATTACATATTTTAGGTTGAAATTATTAAGCACTTTTTTGAAATAATTAAGTAAACTTAGCTGATTCTCACTCATTTAAGCATCAAACTAAATCAATGCATATTTAATAAATTTCCTGAGAATCTCAATTAAGTTTTGTTTAAGTTAAGTAAGTAGATAACCCAAAAATATAGAAATTTATTGACTCCCATTACTATAGCTTTTTAATTAAATTATCATACTTTAGAATTGAGCCTTAAAACATAATTGCTACTGTAGGTTTAGACAAATTGTCACTAAATTAATCTCAAAATTTCCTGACTATTTTACTGTTGATAATTCCGTAGTTAATTTCATAATATAATTTATTTGTAGGATTCATTAACCCCAAACAAGATATTAATTCTTTGAATTTGACAGCTTTTCGTTGTTATTTTTACCTTTTTTTTCGGCAAAGCGAACATAAGGTCTAAAATCAAATCCACTATTTTCTAAATATCTCAAGTCAATTTCTCCCTTTTCTTTGGTAGGGAATTTTTTTTATTTCTAATAATTTAGGTTTTTTTACTTCTACTTCCCAGGAATCAGGAGTTTTATTAATTTATATTTTTTGATAATTTTTTTGATCGTTTCTTTCCTAACATCTATTCCCCATCATTGAGAAATTTTTATTCCAACCTATCTTAAGTTTTTTAAGCTTTCTTTGACCCACTGTTTGACTATATCTTTTTTGTTCCTTACTATATTTAACTTCCTATTTTTGCTTCTTCCTTTGTGATTATATAATTTTAATTCGCTATTTGTTTGCTATTAGTTTGTGATATGTTCGCTATTAATTCATTATTAATTCGCTATTAGTTCACTATATTTAGAAATTATGAATAATCTTTGGGCTATAAGAGACGATTACTAAAAGGCTAATAGTTGAAATTATCCCACTTTATTTTAAGATTTTATTCTATCTGAAGCTTTCTCGCTTCTCGTATAATGCTTAGATAATTCCAATAATTAGGAATATTTTTCTTTCACGGAGCCTTGCAGAGTTTGCTTTAGTCGCGATCGCTATTCCTTTCTTGAACAAATATGTGGGAAAATAGAAAAAACTTGACAACTTCTCCAACAAAAACCTACAGGAACTTTAATAAGCTCAAAAACTATTTTGAACTGAAATAACATGACAGAACAAAAGATGCACGGTAATTACGATCACATTTAAGGGAGGAACCGAATTCGATAATTCTTTCTCCTAAGTTACAATTAAGATAATTTGAAAAAAATTTAATTTAGTTCCTAAGACTTATAGTGTGTTTCATCATCAGTGATGTATGTCTGTGACTGGCAAGAGGCTCGCACTGTAAATACTTGATCATTAATGTTTATAGCTTATATACTCAATGTGATCCAAAATACTTTTTGGTGTACAAACTGGGAATTTTTTGAATATTATCCTAATCACAAAAACTTGAGTACGGCAACTGCGATCATATCTTTACCATTTTCCTCACTTACTGAAGACAAAATCTACTATAAAATAGAAATAGAAACAAAGAATTAAATGACACATAAAATATAAATTGAGGAGGTAATAAATATAGCTATTGTTGATTTTTATATTGCCCATGAAATTGATTCCTAACAAAAATAAATAAATGATTTAATTTGCTAAATTATAGCCTTGTATAAAGATGTGATTACATTAAAAAAAAAGAGTACGGCAACTGCGATCGCATCTTTAACGTTTTCCTCACTTACTGAAAACAAAATCTACTATAAAATAGAAATAGAAACAACAAATTAAATTATACATAAAACAGACATTGAGGAGGTAATAACTATAGATATTGTTAATTTTTTTATGTTGCTCATGATTTCGATTCCTTTAATTAGCTAAATATTAGATGTGATTATATAGCAATCGAAGCAAAGGTTAGGACGTTAACTTAACAGCATAATCAACTCTCAATGCGAAAATTTTCTATTGTTCCTTCTGACTTTCTGACTCGATTTTTAATTGGAAACCAATAATGTTCTATTTCATTTAAGTCAGGAGAATATGGTGGTAAATATTCAAGCTCACAATTCACTGATTCTATTAATTCTCTAACTTTTTGGGATTTATGAAAACTTGCATTGTCTAATATTACTAATTGTCCTGTTTTTAATTGTGGCAACAATTTTTCTCTCAACCATTTTTCAAAAACTACACGGTTACAAGAGCCTTCAAATGTTAATGGAGCAACTAATTTTCCTTCACACAAACCACTTACAATACTTACCCTTAGACTTCTTTTTCCTGACTTTAAATCGTAATATCTTTTTCCCAATTCATTCCATCCATAACCATAATCTTCTCTATTATCCATACCTGATTCATCTATATACACTAGCTGTTCCGGCCTTTTATCGCGAATTTTGGCCAGAAATTTCTTTCTTTTGTCTTCATCTCTTTCTCTGTAACCGTAAGTTTTTTTTTCTTGTATAACCAATTTTTTTTAAGGCTTTACTTATAGTGCGATCGCTTACCTTATCTGGCCATTCATCAGCCATTTCTTTTTGAGTTTTACTGCCATTAATCTGGGCAAATTTTCTGAATTGTTCTAAGTCTGGTATTTTGGGATTATATCCTTTTTGATAACCTGTTTTTGCTTTTATATCCCCAGTTTCTCTTCTTCTATGTAACCAAGTATTGATGGTATTACGACTAATCTTAAATATAGAACTTACTTGAGTTTTACTCATCCCACCATCAATGGCCTTAATAACTTTTTGTCTTAAGTCATAGCTATAAGGAGAAGGCATAATCTTTCCTAGATAATTTTTCGAGCATTATGTCCTAATCTTTGCTTCGACTGCTATACTCAAGAAATAATACGGCAGTTATGATCGCATCTTTTCTTTTTTTATTACTTGTTGAAGAAAAAAAGTCTACTAACTTAAGTAGAAACATCAAAAATAAATAAAATCACATCTAAAACATAAATTTAGGAGATTATAAATATGACTCTTGTTAATATTTATATTGCACCTAAAATAAATTCCTAGCCGAAAGAAATAAATAATTTATTTGAGTTTTTTGCTCCTAGTATAAATCGTGAATTCAAAGGAATAGCATTTACACCAGAAGTTGAAATTTATGAAAAAAACAATGGAATTAATTTAAAACTGGAAATAACCGGTTTGGATAGTAAAGATTTAGATATACAAGCTACTGCTAAAGCAGTTAATTGAAATAAGAGTCAAATCAGACAACCGATAGGGTCACCTGATCAGAGTGAAAGTAGTGACCACTAGGATTAAAACTATAGGCATGAGAGTTATTAGCATTATCAGAAAATAAATAGGGCTAGTAACTTTATAGCAAATGAATCTATTGAACAAAATAAAAGGAATGACTACTTCTGTAACATTATAAGATTGCCTATCAAAATTTTACTGCAAGTATATGCTGCAATGATCTAGTAATTATAATCTTGCGCTGGGAAGGGAGTAATTATTTATTATGGCAGAAAACAGGATTAATTTTGCTAATGTTTTTCTCTGGACTTCTGTTCAGAAAAATCTTCTAAATATTCACAAAATAACTAATTGATTAATTATGCACCAAAATATCTCTTCACTAAGCCATAAAAATTTACCAAGACCTAAGGGTATACCTGGCAACAATTCTGATGCACATATGTATTTATCAATGTATCAAACTATTGCAAAAAAAGAGCATGTAGAAAAGGAACTACGAGATCTAGAGAGGCGAACTAAAAAGGCTAAACAAAAATTGGCTATGCTTGAGGAACAAATAAGCAAATATCCTGCACTATCGCCCGAACTAAAAAATCCAACTCAGTCACAAACGAAACAACACACTAGTATGTTAAAAAAACACAAAACCTTGAACGTATTCGATAAAACCAGCACAACTGGGAGGGGTAGTACTCAGAATGAAACGAAATTTACAACAATTACTATGGGATATTAGTAATTCGTAATTATCTCTCGTTTTGTTGCTCCTTTATGTTTGGAAGTACAGGTTAAGTTTTGGATGAGGTTTATCTCATTGAGTATTGATCCCTCACGGGCTGATAATTAGTGAAAGTTATTGTTAAATAAGGGTTTTAAGGATACATTAAAGGGTTCAAATTGGCGATGACAACACAAAAATATAATTATTATTAGCAAGGGTGTCGGTGAGGGAAGTTCGCCGACACCCGCAGCTAAATTGGATGTATTTTTCAAGTTTGAGACGACAAACACATATTGTGAATAAACTAGGGGTAATTTAATTTTAAAGACATTATATATAGAGATCAGTAAATTAGATGTATTTGCCCTAATGGCTGCCCGAAAAGTTGAAATAAAAATCAACTAAAATTGGGGGGAGAAGGGGTTGGTTCTCGAAGCTAACTAACTTCTTTTCTAGAAATGACGATGATTATTACTAACCGAAAAATCAATATTTTCTAAAAAAGTAGAATTATTTAAATCTTTGTCCGACAATAGTTTGGAGTATATTGTTGCCCTGTTATGAATTGAGCATATCATAGCATTTCAAAAAAGAATTTTATAAATAAGTTAAGTATTATAATCATGTCATAGTAGGCATTTTGAAAGTTAGTATTAGCAGGTAGTAAATAGCTACTGTGAATTTTTATGTTGTGCGTGAAGTTGATCCCGGCAAAAAAATCAATCAATTATTGGCTGGATATTTGCGCTGCTAATTAGCTAAATATTAGTCATTGAGAAAGATGGAATGAACTGAAAAAAAAAAGAGTAGGGAAAGTACCTGAGTTTGTTTCTCGTTTCCCTCACTTACTCAACACATAATTTACTCTAAAGTAGAAAAAGAAATAAGAAATTAATCGTACATAAAACATAAATTTCGGAGGTAATAAAGATGGCTATTGCAAATTTTTCTGTTCTCGGCAATATAGGTTCTTGGATGGGTTTTCCCGTTGTGGATCAAGTTGTGGATCAAATCAATTCCTTGAAAAAAGAAGTAAATTGTTTATCTGAGGTTTCCACTTCTACTATCAATGGTAAAGTTACTTCTACTATAAATGGTAAAGTACAAGAAATAGAGTTTACACCAGAGGTTGAAATCCACGAAAACAATAATGGTATTGATTTAAGACTGGAAATACCAGGTTTAGAATTTCAAGGTTTAGGTCTACAAGTGAATGCTGAAAGAGTAGAAATTAAAGGAAAAAATCGCCAAGACACTGAAGTAGAAGAACAAGATTAAGTTCGTTATGAATTTCATTATGGTGCTTTCCAACGCAGAATTTCTCTACCAGTTAGGGTTCAAAATAACCTGGTAAAGGCTGACTATAAAGATAGTTTTTGCACATACATTTACCTAAAAGTGAAGCTGATAAAAATCAAGTTGTGAAGGTAAATGTTGGCTAAATATTAGTCATTGAGAATGATGGAATGAACTGAAAAAAAAGAGTAGGGAAAGTACCTGAGTTTGTTTCTCGTTTCCCTCACTTACTCAACACATAATTTACTCTAAAGTAGAAAAAGAAATAAGAAATTAATCGTACATAAAACATAAATTTCGGAGGTAATAAAGATGGCTATTGCAAATTTTTCTGTTCTCGGCAATATAGGTTCTTTGATGGGTTTTCCTATTGTGGATCAAGTTGTGGATCAAATCAATTCCTTGAAAAAAGAAGTAAATTGTTTATCTGAGGTTTCCACTTCTACTATCAATGGTAAAGTTACTTCTACTATAAATGGTAAAGTACAAGAAATAGAGTTTACACCAGAGGTTGAAATCCACGAAAACAATAATGGTATTGATTTAAGACTGGAAATACCAGGTTTAGAATTTCAAGGTTTAGGTCTACAAGTGAATGCTGAAAGAGTAGAAATTAAAGGAAAAAATCGCCAAGACACTGAAGTAGAAGAACAAGATTAAGTTCGTTATGAATTTCATTATGGTGCTTTCTAACAAAGAATTTCTCTACCAGTTAGAGCTCAAAATGACCAGATAAAGGCTGACTATAAAGATGGTTTTTGCACATACATTTACCTAAAAGTGAAGCTGATAAAAATCAAGTTGTGAAGGTAAATGTTGGCTAAATATTAGTCATTGAGAATGATGGAATGAACTGAAAAAAAAGAGTAGGGAAAGTACCTGAGTTTGTTTCTCGTTTCCCTCACTTACTCAACACATAATTTACTCTAAAGTAGAAAAAGAAATAAGAAATTAATCGTACATAAAACATAAATTTCGGAGGTAATTAAAGATGGCTATTGCAAATTTATCTGTTCTCGGCAATATAGGTTCTTGGATGGGTTTTCCTATTGTGGATCAAGTTGTGGATCAAATCAATTCCTTGAAAAAAGAAGTAAATTGTTTATCTGAGGTTTCCACTTCTACTATCAATGGTAAAGTTACTTCTACTATAAATGGTAAAGTACAAGAAATAGAGTTTACACCAGAGGTTGAAATCCACGAAAACAATAATGGTATTGATTTAAGACTGGAAATACCAGGTTTAGACTTTCAAGGTTTAGGTCTACAAGTGAATGCTGAAAGAGTAGAAATTAAAGGAAAAAATCGCCAAGACACTGAAGTAGAAGAACAAGATTAAGTTCGTTATGAATTTCATTATGGTGCTTTCTAACAAAGAATTTCTCTACCAGTTAGAGCTCAAAATGACCAGGTAAAGGCTGACTATAAAGATGGTATTTTGCATATATATTTACCTAAAAGTAAAGCTGATAAAATCAAGTGATGAAAGTCAATGTTGGCTAAATATTAGTCATTGAGAAAGATGGAATGAACTGAAAAAAAAGAGTAGGGAAACTACCTGAGTTTGTTTCTCGTTTCCCTCACTTACTCAACACATAATTTACTCTAAAGTAAAAAGAGAAAGAAGAAATTAATCATACATAGAACAAAATTTTCGGAGGTAATAAATATGGCTATTGTTAGTTTTCCTATGGTGGGGGATATAGATTCTTTTATGACTTTTCCTCTTGTGCGTAGAAACAATTCCTTGAAAAAAGAAATGAATTGTTTATCTGAGGTTTTCACTTCTGCTATAAATGGTAAAGCTAAAGAAATAGTATTTACACCAGCGGTGGAAATCTACGAAAATAATGATGCTATTGATTTAAGGCTGGAAATACCAGGTTTAGAAGTTAAAGATTTAGATGTACAAGTGACTGCTGAAGCAGTAGAAATTAAAGGAAAACGTCGTCAAGAAACTGAAACGGAAGAACAAGACTTGGTTCGTTCTGAATTTCATTATGGTGCTTTCCAACGCAGAATTTCTCTACCAGTTAGAGTTCAAAATAACCTGGTAAAGGCTGACTATAAAGATGGTATTTTGCATATACATTTACCTAAAAGTGAAGCTGATAAAAATCAAGTTGTGAAGGTCAATGTTGGCTAAATATTAGTCATTGAGAATGATGGAATGAACTGAAAAAAAAGAGTAGGGAAACTACCTGAGTTTGTTTCTCGTTTCCCTCACTTACTCAACACATAATCTACTCTAAAGTAGAAAAAGAAATAAGAAATTAATCGTACATAAAACATAAATTTCGGAGGTAATTAAAAATGGCTATTGCAAATTTGTCTGTTCTCGGCAATATAGGTTCTTGGATGGGTTTTCCTATTGTGGATCAAGTTGTGGATCAAATCAATTCCTTGAAAAAAGAAGTAAATTGTTTATCTGAGGTTTCCACTTCTACTATCAATGGTAAAGTTACTTCTACTATAAATGGTAAAGTACAAGAAATAGAGTTTACACCAGAGGTTGAAATCCACGAAAACAATAATGGTATTGATTTAAGACTGGAAATACCAGGTTTAGACTTTCAAGGTTTAGGTCTACAAGTGAATGCTGAAAGAGTAGAAATTAAAGGAAAAAATCGCCAAGATACTGAAGTAGAAGAACAAGATTAAGTTCGTTATGAATTTCATTATGGTGTTTTCTAACAAAGAATTTCTCTACCAGTTAGAGCTCAAAATGACCAGGTAAAAGCTGACTATAAAGATGGTATTTAAAGATGGTATTTTGCATATATATTTACCTAAAAGTGAAGCTGATAAAATCAAGTGATGAAAGTCAATGTTGGCTAAATATTAGTCATTGAGAATGATGGAATGAACTGAAAAAAAAAGAGTAGGGAAACTACCTGAGTTTGTTTCTCGTTTCCCTCACTTACTCAACACATAATTTACTCTAAAGTAAAAAGAGAAAGAAGAAATTAATCATACATATAACAAAATTTTCGGAGGTAATAAATATGGCTATTGTTAGTTTTCCTATGGTGGGCGATATAGACTCTTTTATGACTTTTCCTCTTGTGCGTAGAAACAATTCCTTGAAAAAAGAAATGAATTGTTTATCTGAGGTTTTCACTTCTGCTATAAATGGTAAAGCTAAAGAAATAGTATTTACACCAGCGGTGGAAATCTACGAAAATAATGATGCTATTGATTTAAGGCTGGAAATACCAGGTTTAGAAGTTAAAGATTTAGATGTACAAGTGACTGCTGAAGCATTAGAAATTAAAGGAAAACGTCGTCAAGAAACTGAAACACAAGAACAAAATTTGGTTCGTTCTGAATTTCATTATGGTGCTTTCCAACGCAGAATTTCTCTACCAGTTAGAGTTCAAAATAACCTGGTAAAGGCTGACTATAAAGATGGTATTTTGCATATACATTTACCTAAAAGTGAAGCTGATAAAAATCAAGTTGTGAAGGTCAATGTTGGCTAAATATTAGTCATTGAGAATGATGGAATGAACTGAAAAAAAAAGAGTAGGGAAACTACCTGAGTTTGTTTCTCGTTTCCCTCACTTACTCAACACATAATCTACTCTAAAGTAGAAAAAGAAATAAGAAATTAATCGTACATAAAACATAAATTTCGGAGGTAATTAAAAATGGCTATTGCAAATTTGTCTGTTCTCGGCGATCTAGATTCTTGGATGGGTTTTCCTACTGTGGAGCAAATCAATTCCTTGAAAAAAGAAATCAACTATTTATCTGAGGTTTCCACTTCTACTGTAAATGGTAAAGTTACTTCTATTATAAATGGTAAAGTCAAAGAAATAATGTTTACTCCAGCAGTCGAAATCCACGAAAATAATGATGCTATTGATTTAAGGCTAGAAATACCAGGTTTAGAAGTTAAAGATTTAGATGTACAAGTGACTGCTGAAGCAGTAGAAATTAAAGGAAAACGTCGTCAAGAAACTGAAACACAAGAACAAAATTTGGTTCGTTCTGAATTTCATTATGGTGCTTTCCAACGCAGAATTTCTCTACCAGTTAGAGTTCAAAATAACCTGGTAAAGGCTGACTATAAAGATGGTATTTTGCATATACATTTACCTAAAAGTGAAGCTGATAAAAATCAAGTTGTGAAGGTCAATGTTGGCTAAATATTAGTCATTGAGAATGATGGAATGAACTGAAAAAAAAAGAGTAGGGAAACTACCTGAGTTTGTTTCTCGTTTCCCTCTCTTACTCAATACTAAATCTAGTCTAAAGTAGAAGGAGAAAACTCATCTGGGGTTTTCACTTCTACTATTTTTGGTAAAATCAAAGAAATAGCTTTGATACCAGGAAGTGTTGATACCACTAAAGGTGAATTAAGATCTTTTTATGATTATTTTCTAGAGCACCGGAACTCTCGCCTATTCGGTTAAAATAAAATCTGATGGGTTAATTTCCGGGGCATCTTCTAAGGTAGCTATTTTGCCACCACCGCCAAAACCCGGTAGCCGACCTTGGCATTGTAATATAAGTCTCCGGTGGCGCGATCGTAAACGATGTCTGCTACAGATCTCGAAACGGCTTTTTTGTTTTTACAGCAATTTTCAGGTAAATAGACCACAGTGGTTGAACCAACCGAAGGCATCATCTTCAGTAATGAAATTTACAACTTCAGCCATTGCTTGCTCCAGTGATTCATGGGTACGTGCCTCACAAGAACGGAGAAATTGCTTCAGTTTCGACCAACAAAGCTCAATAGGTGATAAATCAGTAGTAAGACCTGGGTTTAATAAAGTGATAAATACCTCAGTATTTGTACTTCCTGGTACAGTCATCGACGCAATCAGTCCATCCAGGTTCAAAGCACCAATCAAAGAAACATTTCCACCCTTGCTACCTGGGATACTACCAACAGCTCGTTCCCCATCTACGGCTCTGGCGAATAAACGAGACATTGACAAATTTATTCGGGCTTCATCAACAAATACTAAATTTCTGACATCAATTTTATCTAACCAACGTCGATAGTCATGTCTTAACTCTTGGACTCTTGGGGTATCTTGCTCACTGGCATAAAGACTTTTTTTTTGCACCGTAAGCCTAATTTTTCTACGGCGCGATGCATTGTGGAGATACTCACCCTAATTCCTGTTGTTTCTTGATAGCGAGCGCATAATTCTCTCAGCAATAAGTCATTTTTCTCCTCTACCAGAGATTTGATGATGTTGAGATTATCATAGGAAATTATTGGCTGCTGATATCCTCCACGTCGTTTGGCCTCAATTTGTCCAAGAGTGACGATAATGACGCAACAAATTTTCGTACCATAGACAAGCTGACCTTAAATCTTTCAGCCAACTGACGTTGAGAGCCTTCTTTTGCTTCCCAAGCTATAATCACGCGACGACGCAAATCACTCGAATACGATACTGGCATTAAATTTAACAATTACATCAAACCCATTTTACCGCACTTTGTGGTTCAATTACCTGAAAAGTGCTGTAATGTCGCTTGTTCCAGATGCTTTACAAATTACAATGATTATTTTTGGAATTAATATTTTAGACATTTTTGCCCAAGGTCAAATAACCTTAAACAGTCAATTGCAAGATAAAGAATTTTAAGAAATAATAGACTTTGTGCTGCTTACCTTTCTGTCTGTATTTTTTTGATAATCCCAAATCTGTTTCCCAATAAGACCAATACCTGCAATAGCAACAACTGCACCACCTGTAGAAATAGCAGAAACAATAGCAGCTCCAGCAACTACTCCACCACCACCTGCAGCTAATGTGCCACCTCCTAACCAAGCTAACGCAGCATTTGTAGCTGCTGCTCCACTTAAAGAACCAATCGCCGTCCCTGTGGAAGCTGCTGCCCCTAAAGTAGATGCAACAGTAACTACTGTACCTGCTGAAGCTCCTGCACAAACCATTGCACCTCCGGTAACCATTGCTGCTGTTGGTATTGCTTTTTGAATAATAAATTTTTGCCATTCTGGGGAAATTTCCACCCAAACTGCTTGAATAACTGAAGCACTTAATAAAACTGCTCCTAATGGTGGATATATAATTACAACAGTTGTGATTATACCTGAAGTGAATGCTTTTAGTCCTACCTGATTAATCGCTTCTTCAAGAGTCATTTTATCCTGTAAAACTTGAATCAGAACAGGAATAACTGATTCTGCCAACGTAAAGCCCAAAGCTGCAAAAGCATTTCCTCCCATTAACCTTTGAATAACTTTGATAGCAGTACCTCGAATAAAACCACTTTTTAAACCATTTATAGCTACTTCAAGGAATTTTTCCAGTTCAGCTTTATCAAGCGCTTGCTCTCCTCTACAATAAGCTGCAATAGTTTTGATAGACCGGAGCAAAATATTAATAGTAGTGTTAATTGACGCACCTGTAATGCCAGCTCCTCCTACTTCTCCTACTAGTGCAGCACCTTCCATTAAGTTAGCAGCTAAATATGGATTTTCAGCAACCCAAACAGCAAAGCCTTTACTAATAGGAAAACTTTTTATCCCATCTACGTTAATTATAGTTTTTGTTCCATATAAACTAGGATTTTCTGAATTAGTAAGTATATCACTTTTGTAGTGTCCAGAATTAACTTGTTTTTCTACATATTCAGAGGTACCTACTTTAGCTTGAATTTCTTCTATAACCTTTCCTACTTTTTCAACATAAATATCAGGGGCATACTTAGTTCCATCTGCGGGGATTTGATAAGCACGAGTTTCAAAGCCTTGTAGTGAAGCTCTAATATTGAAACCAATTGTTTGTAAATGTTCAAAGGCAAAACCAAATGCTTGTGGATTTTCAGTAACTTGATGATTATAGCTGTTAATTAGGCCTGAACCTGGTTCTAGTATTTTTGCAGCTCCGTCTTGAACAGCTTCTACTACTGCTGATATGTTTCTAGTTGTTTCAGGAATTAGACCATTGATAATAGAATCAATTTTATCTTTCATTATAATTTTAGAAAATAGAGAGCTTTTCTTGTTATTATAAAACACATAATTGTTTGCAAACAACAGAATATTTACTGAATTCCGATATTTTTTTTATATTCAGATTGCTTTCATTGTTCGCCGACTAAGAAGCGAGTACAATCTCTATAATAACATTATAATTGCCCACTCGACACAATATTCTACTGCTTTGTACAAAAGTTCTTTAAGAGCTACTTCAGCTATAATTTTTGAGTATTTAAGCCAAAATGAGTCTGAAGAATATTGAGAAAGCGCCCAATCAATACAATAGTCTACTGTTTTGTATAAAAAGTCTTTCGTATTTTTTTTAAATGAAGTTTCTAACAGCATAGGCCATAAATCCTTAGATTTATTTGCAGCAAATCTTGACAGAGAAACAGCAGATTTTGATAGAGACTCGGTAGACTTTGATAGAGATTTGGCAGATTCTAATGAATACCTAAAAGTTTTTCCACTAAAAGATTCTAAGCCTTTCCAGAATGACATTTTTCAATATTAAAATTTTTTAATGATATTTATTTAACAAGATTTATTATTTCTCAATATTAATTAGAAGAATCTTCTAAGTTTATTTTTTCTGTTACTTCTTGTGTTGTTTTATTATATTCTTCTTCTACTTCTTCTAATATATCTTCAAAATTTTTGTCACTTGTAGGTTTGTAATAAGCAATATCTGCTAAGGCTTGCCCCAATTTGCCTTCACGAATTTTTTGCATCATTATTTTTTTGTTTTCTTCCTTTGACAGGTTAGGATTAAAATAACCTTTTAGAGCGTCAAGAAACTTTTCTGGACTTAAGGAAGGTACTACAGTATTTAGTATTTCAAATGCTATTGTAGTTGGATTATTAAGATTCATAGATTTGACTCCTATTTAATATGTAGACATACATGGACTGGAATGACTTTTTTTTGGACATTATTTCTGACTTTTTTTTTGGTATTTTTGACTTTTTTTTTGGTAATTGGTTTGGGAGATGGACGTTTTTTATCATTTTTATAATAGTTTTGGTAGTTATTGCTTTTTGAAACTTACAGATACATACACAAACTTATCCAATCTTAGATTACAAGGATGTGTATTATTATATAGTTTTTTTTTGTTCTAAATTTCCCTTATAAAATCTAATTTTATCTTAATTTTAATACTTAGATTTTCCGTTAATTTCTTAGTAGTTATTTTTTTCTTCTCCAATTCCACGGGTTAATTTGTTGATTTGTTGGCAATCCCCAAAATCCTACTTGTTTATTTTGTGCTTTTTGTTGTGCCACTGCCTGCTGTCTCCAGGTGGGTGGTCTGGTATTTTAAAAGTGTTACAGCATATAAAAACCCAGACTAAATAAAATAATACACTTGTCTATTATTTTTGACAAGTGTTTTTTTTTATTATTTATTTATGTTTTGAATTTTTGATATAGCTTGCTGTGGGTGTTGTACCCGAGGGGGTGATCTGGTATTTTAAGAATTGACAAAAAGACTAAAAATAACAGATCAATTGAATATTACACCGAGTACTTATTTTTTACAAGTGTTTTCACATAGGAACTCTCCTATTAGAAAAACCGACGGATGGTTCACTTGTAAAAATTATCTAACCGACGATTTACTAATATCCCTCTGGAATTCCCCGACAGACATTATCGGCGTTAGATTTGGCCCTAAAACCAAATACTGTCTGTTAGACATTGACATAGACTCCCCCCATCATCCCCGAAACTCAAATAATCTAAGAAATATCCTCGGTTGTCTTGAAGATGTTGGCCTAATAGACCCCGTTCCGATCCAATCCTCCGACTCCGGCTGCCTATATATTTATTACTTCTTACCTGAATTAGTTCCAACCTTTGGGCTAGCCAGTCTATTATCTAATACCTTAATCTCTGCCGGGTTCGACATAAAAAAAGGCCATTTAGAGATATTTCCAAACCCTAAAACATATATTGATACTGAAAATCATAGGGAATATTCCAAATATAATGGCCATCAGAGATATTGTTATCAGAAACATCAGAAGAAGCTAATGAGTACTTGTTTGATTTAAAAGAGAGGCAAGGAAAAAGTAAATATGGGAAATTAACACTATGATCGGCAACAGATTCCACAACTGACCATTACAAAAGGTTTGGCTTCGCTGGAATATATGAAATATAGGTGCAACAGTAAAACTTAGTTGGGTTTTGAGTTGCTTCCGCAGGAATTGAAAATACTTTTCACTTGGTTGATAGGGCAACTTATCAACCTTATTTTTTTTAGGAGGAAATATGTCAACTTGTATTGTTTACTCTGACGGGATAAACCCAAGGACAAACGCTTGGGAAGTAATAGAGAATTTGTTAGTTGAACTCATGAAAAACAACGAGCAAATAATTTTATTTAACAGAAATTCATTAGATCAGTTCACTCAATTTTATCTTACAGCAATTTTCAGGTAAATAGACCACAGTGGTTGAACCAACCGAAGGCATCATCTTCAGTAATGAAATTTACAACTTCAGCCATTGCTTGCTCCAGTGATTCATGGGTACGTGCCTCACAAGAACGGAGAAATTGCTTCAGTTTCGACCAACAAAGCTCACACTTGTGATAAATCAGGAGAGTAAGGGGGCAAAAACTTGACTTGAGCACCGACGGACTCAATGGCAACTCTGACACGTTCAGCATGATGAACCTTGAGATTATCCATTACCACGATTGCCCCTTGCCACAACTGAGGTAGTAAGACCTGGGTTTAATAAAGTGATAAATACCTCAGTATTTGTACTTCCTGGTACATTCATCGACGCAATCAGTCCATCCAGGTTCAAAGCACCAATCAAAGAAACATTTCCACCCTTGCTACCTGGGATACTACCAACAGCTCGTTCCCCATCTACGGCTCTGGCGAATAAACAAGACATTGACAAATTTATTCGGGCTTCATCAACAAATACTAAATTTCTGACATCAATTTTATCTAACCAACGTCGATAGTCATGTCTTAACTCTTGGACTCTTGGGGTATCTTGCTCACTGGCATAAAGACTTTTTTTTTGCACCGTAAGCCTAATTTTTCTACGGCGCGATGCATGGTGGAGATACTCACCCTAATTCCTGTTGTTTCTTGATAGCGAGCGCATAATTCTCTCAGCAATAAGTCATTTTTCTCCTCTACCGGGACTTTAGTGAAAAAATAGTAAAAAAAAGGGTATAATGTATACCTGATATGTATTTTACGTTAATTACTGGCCTGGGAAAAGTTTGATGAAAGAAACAACTTCAGTGGCCATGCCCTCTTGTTTCCATCGATGGTGCGATCGCTTTAACAATGTCTTTAAAACAAAAGCCCAAAAAACAGGGTTTAGGGAATATATAGGAGGATTACTCTTGAGAAAGCGATCGAAAAAACTTGTCTCAAATTGCCAACAACACTGTAGGTCACACGTACCACAAATTACGGCATTTTCTAGTTCGAGCAAATTGGTCTGTAGATGCTGTGAATGAGCGTCGTCTTCAAGTAATGTGGGGGTAGTCCTGTATATGTAGTGATAAAATTACAGTGAAGCGATCGCTTCATTATAATGATTAATGAAATACCAAATAGCTCCTAGATGGTTTTCTAGCTTTTTAGAAAAGGATAAAGTCTTTCTGACCAACCGAGAAATTCTTTGACGCAAAGTATTATCGGGACTTTAGTGAAAAAATAGTAAAAAAAAGGGTATAATGTATACCTGATATGTATTTTACGTTAATTACTGGCCTGGGAAAAGTTTGATGAAAGAAACAACTTCAGTGGCCATGCCCTCTTGTTTCCATCGATGGTGCGATCGCTTTAACAATGTCTTTAAAACAAAAGCCCAAAAAACAGGGTTTAGGGAATATATAGGAGGATTACTCTTGAGAAAGCGATCGAAAAAACTTGTCTCAAATTGCCAACAACACTGTAGGTCACACGTACCACAAATTACGGCATTTTCTAGTTCGAGCAAATTGGTCTGTAGATGCTGTGAATGAGCGTCGTCTTCAAGTAATGTGGGAACGTCGCCAAACAAAACCTTCTCGATCCTATTGCTTTAATTATAGACGATTCAGGCCACAGAAAAAGTGGTAATTTTACTGCAGGAGTAGGGCGGCAATATATAGGAGAAATAGGAAAAACAGATAATGGTGTAGTCGTGGTGACAACTCATCTTTATGATGGAGTTAAAAGTCTACCTTTAGACATAGCTTTGTATCAGAAAGCTGATTCTTTTCCAAAAGGAAAAAAAGACCCAGAATTTGTCAAGAAACCAGACGAGTGCAATGTCTCTAGTAGATCAATGTTTGTCCAGAGGACACCAACCAGAAATTGTGTTAATTGAAATTTGGCTATGGTAACAATACATCATTCTTAAATCAACTAGAGAAAAGAAGTTTAACTTATATAGGAGGATTAGCTAAAAATCGAAAAGTCATCATTAAAAAACAAGATGACATTAAAGAGGAAATTAGATTAGACAAGCTGGCAGAAAGTATACCTCAGAAAGCTTTCAACTTAGTTCAACTAAGTACAAAAAATGCTAGAGAAGTTTGGGTAGCTACATTAGAAGTAGAAATATCTAGGATGTCAGGTCAAAAAACTATAGCTATCGTTATGAATGCTAAAAGTTTTTCTGAGGCCACTGATATTAACTATTATATCACTAATAGAGAAGACAAATATGTAACTCCTGAGTGGATATATTCTACTTATTCTCAAAGAAATTGGGTGGAAGTTTTCTACAGGGAAGCCAAAGGATGGTTAGGATTAAGAGAATATCAAGTCAGAGATAAAATCAGCCTTAAAAGGCATTTTATTTTAGTATTTTGTGCTTATACATTTATTATCTGGCATCAGTTAACAGGAGGTATAAGAAGGCGTTGGGCTAACAAACCATTAAATACGTTTACTGATACTTTAGAAGCATTTCGTACCGCAATATCTTATCGTTTTGTTGAGTGGTTAGATGAAAACATCGACGTATTTACCGCTCATAAAGAGAGTTTAGGGTTTGTTTGGGCTTGAAATTTGCTAAAGTCCCGCTACCAGAGATTTGATGATGTTGAGATTATCATAGGAAATTATTGGCTGCTGATATCCTCCACGTCGTTTGGCCTCAATTTGTCCAAGAGTAACGATAATGACGCAACAAATTTCGTACCATAGACAAGCTGACCTTAAATCTTTCAGCCAACTGACGTTGAGAGCCTTCTTTTGCTTCCCAAGCTATAATCACGCGACGACGCAAATCACTCGAATACGATACTGGCATTAAATTTAACAATTACATCAAACCCATTTTACCGCACTTTGTGGTTCAATTACCTGAAAAGTGCTGTAAAACCTAAGATGCAGGAGTTAAATTGAAACATCTTTATGCAATTTTTGAAACTATGGCATACTCAAAACTCTAAACACTTATTCCCCTCTGCGAATTTTTAGTGCTCCCCTGATGGTCTGTGGTCATAACTTTTTGTCTTTAAGGCTAATACACTATTTTAAAATTGACACGCTACTACAAATTTCTAATAATTAATGCTAGTATAAAGTAAAATATTATCACTAAAAATACAGATTTTTAGCTTAATTTATTGTTTAATAAACTTATACCTACTTTTACTAATAAATGAGGTACTGATAACTGATAATTGAAAATACTATGAATAATGAAACTGATACTCCTGTTAATACCGACAATTATTTATTAAGAAGCGTACATACAAACAATTTCCCTAAAATTTTAGATCAGCTAGGCATATCTTTAGTTGTTTCTACTTATCAAGCAGGTAAATTAATTGTATTGCGTGCCGATAATGGAGTAATTAATACTCACTTTCGAGCCTTTAAGAAACCTATGGGATTAGCAGTAACTAACGAAAAAATTGCTCTGGGAACTGCTTATAAAATTTGGGATTTTCGTAACGTTCCAGCAGTAGCAGAGAAAATAGAACCCCAAGGGAAATATGATGCTTGTTATTTACCAAGAAATATTCATATAACTGGAGATATTGATATCCACGAAATGGCTTGGGTGAAAGATGAATTATGGTTTATTAATACTCGTTTTTCTTGCCTTTGTACTCTCGGTCATCCTAATAGTTTTGTGCCCAGATGGCGACCTCCTTTTGTCACTGGATATGACTTAACAGACCGGTGTCATTTAAATGGATTTTGTTTAAAAAATGACCTACCAAAATATGTCACAGCTTTAGGAGAAACTGATACTGCTGCTGGTTGGAGAAAGAATAAAGCTAATGGGGGAATATTAATAGATATAGAAACAAATGAAGTATTAATTCGGAACTTATCTATGCCTCATTCTCCTAGATGGTATCAAGAACAATTATGGTTATTAGAGTCTGGTAATGGTAGTCTGGCAAAAGTTGATTTAAACCAGAGAAAATTACGAACAATTGCTAAATTACCAGGGTTTACTCGCGGTATAGATTTTTGGGGAAATTTAGCATTTATTGGTTTGTCTCAAGTTCGAGAAACTGCTGTTTTTACGGGTATGCCTATTACTGAACTTCAAGAAAGAATTTGTGGGGTTTGGGTGGTAAATATTTTAACTGGAGAAACTATCGCTTTTTTAAGATTTGAAGCTGGAGTTCAAGAAATTTTTTCTGTGGCAGTTTTGCCTAATATTCGCTTCCCAGAAATTATTGAATGGGATGAAAATTTATTAGCAAATTCCTATGTTTTACCTGATGAAGCTTTAGCAGAAACAATCAAAACAACTGTAGAAATAGCTATGGCAGAAACTCATTTACTTAAAGGAAATAAATTATATCAAAAAGGTGAATTAGTAGAAGCGATCGCTGCATATCAAGAATGTTTGAAGTTACAACCAGATTTGACAATAGCGAAATATAATTTGGGAGTTGCTTTAGGAGATAATCAACAATATGAAGCAGCAATTAATGTTTTAGAACAGGTAATTAATACAGAACCAGATAATGCCGATGTTCAAAATAGTATTGCTTATGCTTATAGTCAAAAAGGTGAATTACACAAAGCAATTAAACATTACGAAAAAGCAATTTATCTCAACGGTAATTTTGCCAAAGCACATTTTAATTTAGGCATAACTTTGTTAAAAAATGGAGATTTAAAACGAGGATTTGCAGAATGTGAATGGCGCTGGCAAACAGGACAATTTACACCCTTTCAATGTCCTCATCCACGATGGAAAGGGGAAGATATTAGCAATAAAATTTTATTAATTCATACTGAGCAAGGAGCAGGAGATGCTATTCAATTTATCCGTTATGTTCCTTTAGCAGCAAAACTTTGTCAAGGTATTATATTGGTCTGTCTACCAGAGTTAATTCCTCTATTTAAAAATATCCCAGAGATTGATAAATTAATGCCACCAGGAGAACTAAAATTATCAGAGTTTGATATCTATGTACCCTTAATGAGTTTACCCTATATTTTCGGCACAACTTTAGAAACAATTCCTGCCAATATTCCCTATCTTCAATCTACAAATAGCAACCCCATAAATCTTACTAATACTCAATATAAAGTAGGCATTGTTTGGAGTGGTAGTTCTACTCATAAAAATGATGGTAATCGTTCTTGCAAAATCACAGACTTTTTACCTATTTTACAGGTACCAGGAGTCAAATTTTATAGTCTACAAAAAGGAGAAAATAGGCAAGAATTAACTCAAGTTCCCAGTAATATTCAGATAGAAGATTTAAGTTATCAGTTAAACAATTATGCTGATACAGCAGCAGTAATAGAGCAACTAGATTTAGTAATTACTGTTGATACTTCTGTGGCACATTTAGCAGGAGCATTAGGTAAAAATGTATGGAATTTATTATGTTTTAATCCGGACTGGCGTTGGTTACAAGAAGTTGAAGATACTCTTTGGTATCCAACCATGAAATTATTCCGTCAGTCTCAGTCAAGAAAGTGGCAAGAAGTTATTGAAAAAGTTCAGGAACATTTGTGGAAAATTATCACAGGAAACATGATTATTAGTAATAAGTAAAACTTTGACTAAGCTATAAATTTAAGTCTTATGCACTCAAATAAGAAACCGGGTTTATTACTCTAATTATTATTTTTCACTATCACAAAATTTTGTCTATCAACCTAGTTTTTGCTTAAGCCCTAATATTATAAGTTTATAAGTGAAGTATGAAGTATTTTACAAATATAATATTTATTAATGATTTAATTTTAATTTATTAATATTTAATATTAATTTTATTTATAATTAATAATAATAAATAGTATTAAAAACCCTAAGTTTTTATAAGGTTATATCTATTTTGGCAAAAACTATAGATATTTATTAGCATTATTATATTTAAGTAAATTTAACTGCTAATATAAAGTCAAGTTTACTGCTGATAAAAAAATAAACTTTGCTAATTTTTTCTATGAATTTTATTTAATTTTGATTGTCTAACTATTAACTGAAAAACATATAATCTTTTGTTAGGTCTAAGTTTTATAGCAAGGTTTGAAAAATGAAAAATGTCAAAAAATAATGCTTGATATTTGAGTAAAAATACTTACGAAAAAATATTACTTCTAACATTTTTATTCTCAGTAATTGTTGATAAGTATTTTGTATTTTGGTTACTCAAATAGCTACCCAAGAGTTATTGTCTTGATCCAGGCTTAGACGAAGTCCGTGGAATTTCGATAATGCATCGTGGTAGAAAACTTTTATACCACATTGGGAGATATCCCCAAAGCTGGTTAAACCTTGCTATATGTTTTTAACAAATGTCAGTATTCACAGTATTGGGAAAAATTTATTCTTATTGGATATAGTGGCATTGAATTAGTAGTAACCTGATTAAAATTAACAGATGAATTAGTCTAAGTAAGAATTCACTCTATTTGCCTAGCCGTAATTTTTAATCGCTTCGGTAGAGGGTAGTAGTGAGTAGGTAAGGATGTTGAATAGAATTTTTGTAACCAGTAAGAAATAAATTTACTCCACCTACTTTTATTTGGGTTTTATTTATAGGTAAAAAAGTGGAAATTACTCAAGCGATCGCCCTAACTCCTGAGCTCCTTCCTCAACCCCGACTTATTTATACTGAGTCTAGTATTAACGGGACTTTAGTGAAAAAATAGTAAAAAAAAGGGTATAATGTATACCTGATATGTATTTTACGTTAATTACTGGCCTGGGAAAAGTTTGATGAAAGAAACAACTTCAGTGGCCATGCCCTCTTGTTTCCATCGATGGTGCGATCGCTTTAACAATGTCTTTAAAACAAAAGCCCAAAAAACAGGGTTTAGGGAATATATAGGAGGATTACTCTTGAGAAAGCGATCGAAAAAACTTGTCTCAAATTGCCAACAACACTGTAGGTCACACGTACCACAAATTACGGCATTTTCTAGTTCGAGCAAATTGGTCTGTAGATGCTGTGAATGAGCGTCGTCTTCAAGTAATGTGGGAACGTCGCCAAACAAAACCTTCTCGATCCTATTGCTTTAATTATAGACGATTCAGGCCACAGAAAAAGTGGTAATTTTACTGCAGGAGTAGGGCGGCAATATATAGGAGAAATAGGAAAAACAGATAATGGTGTAGTCGTGGTGACAACTCATCTTTATGATGGAGTTAAAAGTCTACCTTTAGACATAGCTTTGTATCAGAAAGCTGATTCTTTTCCAAAAGGAAAAAAAGACCCAGAATTTGTCAAGAAACCAGACGAGTGCAATGTCTCTAGTAGATCAATGTTTGTCCAGAGGACACCAACCAGAAATTGTGTTAATTGAAATTTGGCTATGGTAACAATACATCATTCTTAAATCAACTAGAGAAAAGAAGTTTAACTTATATAGGAGGATTAGCTAAAAATCGAAAAGTCATCATTAAAAAACAAGATGACATTAAAGAGGAAATTAGATTAGACAAGCTGGCAGAAAGTATACCTCAGAAAGCTTTCAACTTAGTTCAACTAAGTACAAAAAATGCTAGAGAAGTTTGGGTAGCTACATTAGAAGTAGAAATATCTAGGATGTCAGGTCAAAAAACTATAGCTATCGTTATGAATGCTAAAAGTTTTTCTGAGGCCACTGATATTAACTATTATATCACTAATAGAGAAGACAAATATGTAACTCCTGAGTGGATATATTCTACTTATTCTCAAAGAAATTGGGTGGAAGTTTTCTACAGGGAAGCCAAAGGATGGTTAGGATTAAGAGAATATCAAGTCAGAGATAAAATCAGCCTTAAAAGGCATTTTATTTTAGTATTTTGTGCTTATACATTTATTATCTGGCATCAGTTAACAGGAGGTATAAGAAGGCGTTGGGCTAACAAACCATTAAATACGTTTACTGATACTTTAGAAGCATTTCGTACCGCAATATCTTATCGTTTTGTTGAGTGGTTAGATGAAAACATCGACGTATTTACCGCTCATAAAGAGAGTTTAGGGTTTGTTTGGGCTTGAAATTTGCTAAAGTCCCGTTAATTAAGGATCTAAATTTCAGCATTTTTGATTTTTGGGAATGCTTAGCAAACAGAGATCGGCGAGAAATTTAAGGGGACTTAACGGCTTTGTTGCATGAATGTTGCGATCGCAGATGACTCCCTGGAGAGATGCAGTTCTAGATGTGTACTTGATAACTTTCGGGTTTACCATTCTGTATCATGGGGTTCAGGATAGCGCATTGAATGAATAACTCCACTGCTTGATTATCAAATTATCGTCTTCGTAACTTCCCACCAAATAAAACTTTGAACCTAAACATAGTAGACATCTCCAAAATAAAAAATAAGGTAAAATTATCAAAACCATTTATTTATAAAGTCTCCCAAATGAATCCAACTTTAGAATATATTTATAACCATCCAAAAGAAACAAAAAGAATTATTGGCATTACTTATGAACAGCTAATAAAATTAATCGCAAAGGCCCAAATAATAGAATCAGAGAAAAAGAAGGCGATCGCTAAAACAGAAAAAAGATTAATTAAAGCAGGTGGAGTCAGAAAAAAGAATTTAACAAAGGAGGAAGAAATAATTTTAACGTTATTTTATTTACATCAAATACCGACTTTTCAAACATTAGGAATTAACTTTGGTATAAGTGAATCAAGTGCTAATAATATTTTTCATTACTGGATAGATATTCTCAGAGAATTACTGCCAGCAAGTTTATTAGAACAAGTAAAAAAAAAAAGAAAATGAATTGGAATGGTTAAAGGAGATATTAACAGAATTAGAATTAATTGTAGATAGTACAGAACAAAGTAGAGAAAGACCAAGTGAATATAAAGACCAAGAAAAATATAAAATATGAAAAAATAAAAATCATACTTTTAAAAATCAAATAATAACGACACCAAAAGGAACAGAAATAGTAGATGTAATAGTAGGAGAAAAAGGTCCAGTAAATGATGTAAAAATATTAAGAAAACAACAGGATAAATTTGATAAAAAACAAAAATTTCAAGGAGATAAAGCTTATGAAGGAGTAGAAAGAACTACTACACCAAAAAAGAAACCAAGAAAAAAAGAAATGCCGCTAGAAATCAAAGAAGAAAATCAAGAAAAAGCCAGAAAGAGAATATTTGTAGAACATGTAATAAGATTAATTAAAATATTTGGAATTGCTAGAGAAAGATTCAGATTAAAAGATAATAATTATCAAAAAGTAATCTTAACAATATGTGGTTTAGTGCGACTAAGAATTGGATCTTTTATATTAGCATAAACCATCAAAAGCTGAGATAAAAATAATAAATTAAAGTACAATAAATATTTGAATTAGTAACACAAAGTATCTCTGATGCCCATAAAACTGTACAAATTAACTATCTTCATAAGTAGCGATCGCACCACTAAAGATAGTTAGGATAAGCGTTTGAGTATTTTTGGAGATGTCTAGTGGTTTCAGATAGAGAGCGTCTATGGTATCCACTTTCATGCTTCCATTTTTGCCGTCCTATTTGACGAATTCCTCTGAGGTTCTCATCTCTGGGAGCGGGTAGGGCTTTACAGTTGCCATGCTGCCTAATCACAGCATTTTTACGCGGTGGAATGGTCGTTTTTATGCCTCCTTGGTGAGCTGTTTCATAGCACTTGTATTTGTCATCAGCCCCATCACCTGAAACTTGGGCTATTTCACCTTCTACTCCATCTAATAGGTCAGAAAATACTTGGTCGTCACTCACATCATTGGTTGTGACAACTGCTGTGACAATCTCTCCGGTGGCCTCATTCACACTCTAGTAATTTACGCCATGTCCTACGTTTACCTACACCATGAATCCTGGTTTTCCATTCCCCTTCACCGTAGACTTTGACCCCTGTAGAATCAACTACCAAATGCATCCCTTCTGTCCTTGGTTTCACTGGTATCCCGATATTTAGTTTTCTGACCCTACGGCATACAGTGCTATGGTCTGGTACAGGTAAATCTAATCTCTAAAAATCAAATATAGATTCTACAAATCCTTCTGTCTGTCGCCCCGCCCTGCAAACAAACTACTGAGAGTGACCATTAGTTCAATAGCTACATCGCTATAGGTATTCGATGCTCCCTGACGTCCAGTTTGATGTTGATTTACCAACTGTTCTATCACTTCATAACTTAGCCAAAATGTCAGGCTCCCTCTCTGCTTTAAGGAGGCATCATCCATACGACCAGTTGCTAACCCGGTACTTGGACTTGGACTTAGACTTGGACTTAGACTTAGACTTGGACTTACTCATAAGGAGAGTTAATGCAGGATTTTGTGCTACCCACTGTTATTTTTACCATCTTTCCTTGCTTTGTGCAACAAAGCATAATTATATTATAAACAATCTTAACTGAATGGAACCAAAGGCCTAACTTATTTAGACTAAATCAACCAACAGATATTCTTAAAGATTTATTGCAAGATAAACGGTCTCCTGCTACTAGACATGGTTATGAAAGGGATTTAAAGGAATTTTTCAATTATGCAGTAGGTCAGTTACCCACACCAGAAATAGTCCAACAGTTCTTAAACCTAGACGAATTTACAGCCAAACAAATAGTCTTGAGTTATCGACGTTGGTTGTATTCTAAAGACCTCAAACCAGCAACAGTAAATAGAAAACTAGCAGCCATAAAAGCTTTAGTTAAGTATGCAAAAAGAATAGGCAAGAGTTGTTATGACCTAACTGACATACAAAGTGATAAAGTAATTCCCTACAGAGATACAACTGGACTACCAGTGTCACAGATTACAGCAATTTTCAGGTAAATAGACCACAGTGGTTGAACCAACCGAAGGCATCATCTTCAGTAATGAAATTTACAACTTCAGCCATTGCTTGCTCCAGTGATTCATGGGTACGTGCCTCACAAGAACGGAGAAATTGCTTCAGTTTCGACCAACAAAGCTCACACTTGTGATAAATCAGGAGAGTAAGGGGGCAAAAACTTGACTTGAGCACCGACGGACTCAATGGCAACTCTGACACGTTCAGCATGATGAACCTTGAGATTATCCATTACCACGATTGCCCCTTGCCACAACTGAGGTAGTAAGACCTGGGTTTAATAAAGTGATAAATACCTCAGTATTTGTACTTCCTGGTACAGTCATCGACGCAATCAGTCCATCCAGGTTCAAAGCACCAATCAAAGAAACATTTCCACCCTTGCTACCTGGGATACTACCAACAGCTCGTTCCCCATCTACGGCTCTGGCGAATAAACGAGACATTGACAAATTTATTCGGGCTTCATCAACAAATACTAAATTTCTGACATCAATTTTATCTAACCAACGTCGATAGTCATGTCTTAACTCTTGGACTATTGGGGTATCTTGCTCACTGGCATAAAGACTTTTTTTTTGCACCGTAAGCCTAATTTTTCTACGGCGCGATGCATGGTGGAGATACTCACCCTAATTCCTGTTGTTTCTTGATAGCGAGCGCATAATTCTCTCAGCAATAAGTCATTTTTCTCCTCTACCAGAGATTTGATGATGTTGAGATTATCATAGGAAATTATTGGCTGCTGATATCCTCCACGTCGTTTGGCCTCAATTTGTCCAAGAGTAACGATAATGACACAACAAATTTCGTACCATAGACAAGCTGACCTTAAATCTTTCAGCCAACTGACGTTGAGAGCCTTCTTTTGCTTCCCAAGCTATAATCACGCGACGACGCAAATCACTCGAATACGATACTGGCATTAAATTTAACAATTACATCAAACCCATTTTACCGCACTTTGTGGTTCAATTACCTGAAAAGTGCTGTAAACAAATACTCCAGTCGCCAAATACTAATCATTTTCAGGGAAAAAGGGACTACGCAATATTAAGACTACTTTGGGATAACGCCTTACGCCGGAGTGAAGTAGTAGCCATTGATATAGGAGATATAAGCTTAAGCGATCGTACTATTTGGATAAAAGGTAAAGGTACACAGGATAAAGAACGTATCACCATTAACCATAGAACAGTTGCAGCATTAAAAGATTATTTATCAATTAGAAAAGGTGGCATAAACGACCTATTATTTATCAGTCTTAGTTCTGCTAATTGGGGTAACAGATTGGCTGATGATACTGTGTACAACTTAGTAAAACGCACTTGTTCCGAACTAGGAATAGACAAACCCATGTCGCCACATAAAATCAGACATTCTGCCATTACTCATTTTCTAGACAAATCTGATGGAGACATTAGAAAAGTACAACAATATTCTCGTCATAAAAATGTGCAGACAGTTTTAGTCTATGACGACAATAGAAAAGACTATCAAGAACAAATGACTGATCTTATGGGAGAAGATTTTTAG

Protein sequences of DBSCAN-SWA_6

>NC_008312|4685402:4740814|4717394_4717772_+|WP_044136841.1|DBSCAN-SWA
MHQNISSLSHKNLPRPKGIPGNNSDAHMYLSMYQTIAKKEHVEKELRDLERRTKKAKQKLAMLEEQISKYPALSPELKNPTQSQTKQHTSMLKKHKTLNVFDKTSTTGRGSTQNETKFTTITMGY
>NC_008312|4685402:4740814|4688862_4689375_-|WP_011612542.1|DBSCAN-SWA
MDSQKLISGLYNLTELEQLINSQATFWRPLVFTNGCFDLIHAGHVRYLWATKSLGRSLIVGLNSDWSVQNLKPQKEGYPMRPIIPQTQRAEVLAALKPVDGVVIFNETTATKIIERLKPDIYVKGGDYSVETLPEAQKVKNYGGKVSIIQIEVPTSTTGIINSILPKNSV
>NC_008312|4685402:4740814|4699865_4700720_+|WP_011612548.1|DBSCAN-SWA
MSLRWLILAVCIGSELFYFSIQTLPKKLPDLESSATQIQSKNCTNCNNFCTIKELKSLAKSITVKIISENGWGSGIILKREKKVYTIVTNQHVLDTNYKSYLIQTPDGLFYQANQIENEGFQGNDLALLKFRSTNSNYTVASLENSATLSPGDKTFAAGFSALEKTQYIELLFTRGKISILSDRPLEKGYQIGYTNLIKKGMSGGPLLNIYGQVVGINGMHAYPLWGDPYVYRDGSQPTESLRQQMSHLAFAIPIETVAKLAPNLHLYKLLSSRKFLLARKRQK
>NC_008312|4685402:4740814|4698376_4698835_+|WP_011612546.1|DBSCAN-SWA
MPPKAYLKQYLTIEELKIRYRQAPDTIESRRWHLLLLIAQKWSIKKAAQVVGLNYDYAKEIFGRYNREGPESVKNRSKNRQPPPAKSLLTPEQQQELLVALQGPAPDGGLWSGPKVAHWIAKKTGRSHVWPQRGWDYLKKLGIDWKKKYHND
>NC_008312|4685402:4740814|4722703_4723204_+|WP_011612559.1|DBSCAN-SWA
MAIANLSVLGDLDSWMGFPTVEQINSLKKEINYLSEVSTSTVNGKVTSIINGKVKEIMFTPAVEIHENNDAIDLRLEIPGLEVKDLDVQVTAEAVEIKGKRRQETETQEQNLVRSEFHYGAFQRRISLPVRVQNNLVKADYKDGILHIHLPKSEADKNQVVKVNVG
>NC_008312|4685402:4740814|4708722_4709409_-|WP_011612551.1|DBSCAN-SWA
MINWLVLNAVILIVAYLLGATPSGYWIGSWFYGVDIREQGSGSTGATNVLRTLGNVPALVVLVIDIFKGALAIALVRYIYSLVFAQNLTIIAGVTDIDTAKEWMVIIAGLIAIVGHTKSIWIGFKGGKSVASSLGILLAISWVVGLGTLSVFIVVLTISRIVSLSSIIAAISVSGLMFFTGQPLPYQIFAITGGIYVIWRHISNIERLLACKEPRIGQKLSTEQKMNK
>NC_008312|4685402:4740814|4738473_4738668_-|WP_052845806.1|DBSCAN-SWA
MDDASLKQRGSLTFWLSYEVIEQLVNQHQTGRQGASNTYSDVAIELMVTLSSLFAGRGDRQKDL
>NC_008312|4685402:4740814|4737867_4738251_-|WP_063823344.1|transposase|DBSCAN-SWA
MNEATGEIVTAVVTTNDVSDDQVFSDLLDGVEGEIAQVSGDGADDKYKCYETAHQGGIKTTIPPRKNAVIRQHGNCKALPAPRDENLRGIRQIGRQKWKHESGYHRRSLSETTRHLQKYSNAYPNYL
>NC_008312|4685402:4740814|4739502_4739862_-|WP_052845807.1|DBSCAN-SWA
MQKKSLYASEQDTPIVQELRHDYRRWLDKIDVRNLVFVDEARINLSMSRLFARAVDGERAVGSIPGSKGGNVSLIGALNLDGLIASMTVPGSTNTEVFITLLNPGLTTSVVARGNRGNG
>NC_008312|4685402:4740814|4713251_4713545_+|WP_011612555.1|DBSCAN-SWA
MTILTNFLRSLLLTTIFSFITPIILIGVSWVSFTLISRLPSLQGIGQSGIDQMWELLATFGSGHPWQGCLVIAITCSLVGAMFDTYVFYQNSPKKWV
>NC_008312|4685402:4740814|4731691_4734034_+|WP_011612567.1|DBSCAN-SWA
MNNETDTPVNTDNYLLRSVHTNNFPKILDQLGISLVVSTYQAGKLIVLRADNGVINTHFRAFKKPMGLAVTNEKIALGTAYKIWDFRNVPAVAEKIEPQGKYDACYLPRNIHITGDIDIHEMAWVKDELWFINTRFSCLCTLGHPNSFVPRWRPPFVTGYDLTDRCHLNGFCLKNDLPKYVTALGETDTAAGWRKNKANGGILIDIETNEVLIRNLSMPHSPRWYQEQLWLLESGNGSLAKVDLNQRKLRTIAKLPGFTRGIDFWGNLAFIGLSQVRETAVFTGMPITELQERICGVWVVNILTGETIAFLRFEAGVQEIFSVAVLPNIRFPEIIEWDENLLANSYVLPDEALAETIKTTVEIAMAETHLLKGNKLYQKGELVEAIAAYQECLKLQPDLTIAKYNLGVALGDNQQYEAAINVLEQVINTEPDNADVQNSIAYAYSQKGELHKAIKHYEKAIYLNGNFAKAHFNLGITLLKNGDLKRGFAECEWRWQTGQFTPFQCPHPRWKGEDISNKILLIHTEQGAGDAIQFIRYVPLAAKLCQGIILVCLPELIPLFKNIPEIDKLMPPGELKLSEFDIYVPLMSLPYIFGTTLETIPANIPYLQSTNSNPINLTNTQYKVGIVWSGSSTHKNDGNRSCKITDFLPILQVPGVKFYSLQKGENRQELTQVPSNIQIEDLSYQLNNYADTAAVIEQLDLVITVDTSVAHLAGALGKNVWNLLCFNPDWRWLQEVEDTLWYPTMKLFRQSQSRKWQEVIEKVQEHLWKIITGNMIISNK
>NC_008312|4685402:4740814|4737356_4737740_+|WP_044136842.1|transposase|DBSCAN-SWA
MITTPKGTEIVDVIVGEKGPVNDVKILRKQQDKFDKKQKFQGDKAYEGVERTTTPKKKPRKKEMPLEIKEENQEKARKRIFVEHVIRLIKIFGIARERFRLKDNNYQKVILTICGLVRLRIGSFILA
>NC_008312|4685402:4740814|4704794_4706996_+|WP_011612550.1|DBSCAN-SWA
MTISRSSQLNSTSNIHNLSNPGQISGAKFNDINFNAILDPGELGLRDITLYLDLNQNKFLDEGEPATITGVNGEYSFRNLPPNTYILREISPIGFASTTPDPILNVIPGSNLIVNVGNVSNRGQISGAKFNDINSNGKFDSGEFGLQDITLYLDLNQNQFLDNGEPVTITDVNGEYSFQNLPPNTYILREISPTGFTPTTPDPILNLTPNSNLIANIGSVSNRGQISGTKFNDINSNGKFDPGEFGLQDITLYLDLNQNGFLDEREPATITGVNGEYSFQDLPPNTYILRDISPTNFISTTPKSILNVTPGSNLIANIGSVNNQGSISGIKFNDTNTNGIFDPGELGLQNITLYLDLNKNGLLDGEEPSTMTNVNGEYSFQNLPVNTYIIRENQVSDFIQTTPDPIINVTPGSNIRNINIGNVNNRGKISGTKFNDTNTNGMFDPGELGLADIALYLDLNQNGFLDEEEPSTITDVNGEYSFQDLPSNTYILREISPPGFAKTTPEPVVNVTPGSNITNINIGNVNNRGEISGTKFNDTNTNGILDPGESGLANITLYLDLNKNELLDEGEPQTITDVNGEYSFQDLPPNTYIIRDDQVIDLDQTTPDPIVNITPGSNIRNINIGNVSNRGEINGIKFNDKNTDGILNPGENGLGNFTLYLDLNDNSLLDFGEPATITDEFGFYSFKDLPPNVYIIREVQKIGFSQTTTDPVVNVTPGSNINDINIGNFNEFI
>NC_008312|4685402:4740814|4712275_4713073_-|WP_071820691.1|DBSCAN-SWA
MSKIFFNFSLGLWGQRMLAATYLAGQVFVHLFHGKIYRRNTIEQMAIVGPESLLIVLLTASFVGMVFTIQVARELVAFGTANMVGGMLALTLSRELGPVLTAVVVAGRVGSAFAAEIGTMKVTEQIDALYILKTDPVDYLVIPRVIACGVMMPILTLLCLVAAIFGGLIIAVNLYDIPQSMYIDSVRSFLTLWDLCSGLTKSVVFGVLIAVIGTSWGLTTTGGAKGVGKSTTTAVVTSLISIFIFNFFLSWAMFQGMGGAMKQGL
>NC_008312|4685402:4740814|4709745_4710915_-|WP_063823343.1|DBSCAN-SWA
MYPDKIQPKEPKEPLTKTSVNSDNLNQIIPEATDLDEKIKIETLSTDSSSLTEDSTTAPVDKNEKELTTVVIDRLQQQQNLKEEIATLQEIKAKLQQEVIAQTKAIGSLVPEALSQLEQHKQTLQIEVEKLEHRKERIEKEMRTTFAGTSQDLAIRIKGFKDYLVGSLQDLAAAAEQLELTPQKEEYPTPIVEDVPISVNNYENPKFAEMGFEEQTRQIRQIMEEYRKMPDYYGLPWKLRRTFEPIHAERVSNWFFSQGGRGSLRTMGSRLQNILVASAIVSILRDLYDTRLRPLILANSPERLGEWRRGLQDCLGIDRRDFSPERGVALFEESEVLAQKADRLVRQGKLPIIVIDDTEDKISLSMLQFPLWLAFAPELNSQNSTDKFY
>NC_008312|4685402:4740814|4702431_4703958_+|WP_011612549.1|protease|DBSCAN-SWA
MRFQKKLWDLIFFLFPIKQLLISFSLLLISPTLIFFKQPAAIALMADKINQISTEFTVLIDAINPASGVIISRKKDTYYVLTANHVVETQDEYAIFTKDGERYEVDYQKIIKLPGVDLAVVEFRSSKNYQVATLADYNYQAEFRHVFVSGWPDSRLPFDEKEHLFSPGLLINKDYELAFIKDPISNGYELFYNNITKVGLSGAPVLDTQGRVIGIHGASEGTKIYDEESNSVERVSIGFSYGIPINIFLKLADKLNMGLNFQLEYSSPPPLTQKEAFSIEAYLKVPETRDISSAVAWANHGNYLYRLDKFEEALVAFERSIKIRKNFYPAWYGKANVLSALGRYDTAIDCYKKTVKIKPDFYLAWRDKGALFAYLNRHYEALISFNQVIRYKPNDFAVWYLRGNILTTHFQEYKEAIAAYNRAIELKPNFAYAWIGKGEAFYRLGNYEKAREVAQKAVKLKPNDPEFLTFLNILEKHSLPSAPIKPIPNKGKVEIINYPSRKQPNLLW
>NC_008312|4685402:4740814|4729255_4729492_-|WP_155994444.1|DBSCAN-SWA
MLELENAVICGTCDLQCCWQFETSFFDRFLKSNPPIYSLNPVFWAFVLKTLLKRSHHRWKQEGMATEVVSFIKLFPGQ
>NC_008312|4685402:4740814|4739399_4739510_-|WP_081432459.1|DBSCAN-SWA
MDNLKVHHAERVRVAIESVGAQVKFLPPYSPDLSQV
>NC_008312|4685402:4740814|4685892_4686351_-|WP_011612539.1|DBSCAN-SWA
MLKFKISRIQNKQEKENMYYQRWVVLRKPIDMERGTEKDESDDDDSSLHFIAVYEEQIIGSARLRQLSTELGSISYVAVLPKFQSQGVGTALIQKIIEIAKEKQLKSLRVMSRLSASKFYEKIGFISTGQQLNFLGIPHQFMLFNLPDVQNL
>NC_008312|4685402:4740814|4722058_4722535_+|WP_011612558.1|DBSCAN-SWA
MAIVSFPMVGDIDSFMTFPLVRRNNSLKKEMNCLSEVFTSAINGKAKEIVFTPAVEIYENNDAIDLRLEIPGLEVKDLDVQVTAEALEIKGKRRQETETQEQNLVRSEFHYGAFQRRISLPVRVQNNLVKADYKDGILHIHLPKSEADKNQVVKVNVG
>NC_008312|4685402:4740814|4723642_4724131_-|WP_011612560.1|DBSCAN-SWA
MQKKSLYASEQDTPRVQELRHDYRRWLDKIDVRNLVFVDEARINLSMSRLFARAVDGERAVGSIPGSKGGNVSLIGALNLDGLIASMTVPGSTNTEVFITLLNPGLTTDLSPIELCWSKLKQFLRSCEARTHESLEQAMAEVVNFITEDDAFGWFNHCGLFT
>NC_008312|4685402:4740814|4728609_4728720_-|WP_081432459.1|DBSCAN-SWA
MDNLKVHHAERVRVAIESVGAQVKFLPPYSPDLSQV
>NC_008312|4685402:4740814|4694428_4696336_+|WP_011612545.1|DBSCAN-SWA
MHLSEITHPKQLHNLSIHQLEEIARQIREKHLETVATSGGHLGPGLGVVELTLGLYQTLNLDRDKVIWDVGHQAYPHKIITGRYHNFHTLRQKDGIAGYLKRCESKFDHFGAGHASTSISAGLGMALARDMKGDNFKVVSIIGDGALTGGMALEAINHAGHLPKTNILVVLNDNEMSISPNVGAISRYLNKMRLSPPIQFLQDNLEEQFKQIPFVGETFTPEMEGLKGGMKRLAVSKVGAVIEELGFTYMGPVDGHNLEELITTFNQAHQIPGPVLVHVATTKGKGYPVAEEDKVSYHAQNPFNLATGKALPASKPKPPKYSKVFAHTLVKLAENNPKIIGITAAMATGTGLDKLHGKLPKQYIDVGIAEQHAVTLAAGLASEGMRPVVCIYSTFLQRAYDQIIHDVCIQKLPVFFCLDRAGIVGADGPTHQGMYDIAYLRCIPNMVVMAPKDEGELQRMVLTGIKHTDGAIAMRYPRGNGYGVPLMEEGWEAITIGKGEILRNGDDVLILGYGSMVYSAMQTAEILSEHGVAATVVNARFVKPLDTELILPLAQRIGQVVTMEEGCLMGGFGSAVTEALMDNNVLVPVLRLGVPDKLVDHAKPDESKADLGLTPSQMAERILQSFKPRLSTINV
>NC_008312|4685402:4740814|4720767_4721199_+|WP_044137578.1|DBSCAN-SWA
MTFPLVRRNNSLKKEMNCLSEVFTSAINGKAKEIVFTPAVEIYENNDAIDLRLEIPGLEVKDLDVQVTAEAVEIKGKRRQETETEEQDLVRSEFHYGAFQRRISLPVRVQNNLVKADYKDGILHIHLPKSEADKNQVVKVNVG
>NC_008312|4685402:4740814|4711162_4711555_-|WP_011612553.1|DBSCAN-SWA
MTTISTSQAKQAIELAPSYKIPLVLIIAALPLAFIQKWVSIAIAILGLFLLIQTITIRLKFTETALEVYRSEKLLRNFPYQDWLNWEIFWSPIPILFYFREIKSIHFLPIIFDPKMLRTCLENNFPLNQD
>NC_008312|4685402:4740814|4691159_4692008_+|WP_044136838.1|DBSCAN-SWA
MKATSIRQYSSIAARTLIIVGVIMILSSILDFIVLSVPSNIENIYSKTWQINLATQIVDRGIIPMIGMALLFTGYWVRSNSGLQNNSTSSILDLRFWALLLASLLALIYLLLFPLHLNNTRLDKAELIQRIEQQASQAETQLKARLSSNEFKNQIQERRTQLKNQLTTLLEDETRLNEALENEELPDQLKTLLKTSKTNNNSQAINEFINDQFKQLPNQLTMRIRDRKQELEKQANRNSFKSSLRTGISSLLLAVGYIMIGWTGLKNMGIIKGKGSRQNPAR
>NC_008312|4685402:4740814|4726161_4726524_-|WP_011612562.1|DBSCAN-SWA
MSFWKGLESFSGKTFRYSLESAKSLSKSTESLSKSAVSLSRFAANKSKDLWPMLLETSFKKNTKDFLYKTVDYCIDWALSQYSSDSFWLKYSKIIAEVALKELLYKAVEYCVEWAIIMLL
>NC_008312|4685402:4740814|4728712_4729072_-|WP_052845805.1|DBSCAN-SWA
MQKKSLYASEQDTPRVQELRHDYRRWLDKIDVRNLVFVDEARINLSMSCLFARAVDGERAVGSIPGSKGGNVSLIGALNLDGLIASMNVPGSTNTEVFITLLNPGLTTSVVARGNRGNG
>NC_008312|4685402:4740814|4685402_4685561_+|WP_011612538.1|transposase|DBSCAN-SWA
MIEPLGAKVLNLSKCSPDFNPIELWWLQLKSFISSFYPTTTEMVDTVISVAF
>NC_008312|4685402:4740814|4687979_4688210_-|WP_011612541.1|DBSCAN-SWA
MLGKYLSKKVGGFKQYKNAQVKIAKFHGKQKNIKTDFMDKLSTKIISENQTIDFCRGIICFFSGQKRNPSPRGLGL
>NC_008312|4685402:4740814|4715751_4716598_-|WP_076611779.1|transposase|DBSCAN-SWA
MPSPYSYDLRQKVIKAIDGGMSKTQVSSIFKISRNTINTWLHRRRETGDIKAKTGYQKGYNPKIPDLEQFRKFAQINGSKTQKEMADEWPDKVSDRTISKALKKLVIQEKKTYGYRERDEDKRKKFLAKIRDKRPEQLVYIDESGMDNREDYGYGWNELGKRYYDLKSGKRSLRVSIVSGLCEGKLVAPLTFEGSCNRVVFEKWLREKLLPQLKTGQLVILDNASFHKSQKVRELIESVNCELEYLPPYSPDLNEIEHYWFPIKNRVRKSEGTIENFRIES
>NC_008312|4685402:4740814|4738833_4739259_+|WP_081432461.1|DBSCAN-SWA
MLTEWNQRPNLFRLNQPTDILKDLLQDKRSPATRHGYERDLKEFFNYAVGQLPTPEIVQQFLNLDEFTAKQIVLSYRRWLYSKDLKPATVNRKLAAIKALVKYAKRIGKSCYDLTDIQSDKVIPYRDTTGLPVSQITAIFR
>NC_008312|4685402:4740814|4740160_4740814_+|WP_081432462.1|integrase|DBSCAN-SWA
MITRRRKSLEYDTGIKFNNYIKPILPHFVVQLPEKCCKQILQSPNTNHFQGKRDYAILRLLWDNALRRSEVVAIDIGDISLSDRTIWIKGKGTQDKERITINHRTVAALKDYLSIRKGGINDLLFISLSSANWGNRLADDTVYNLVKRTCSELGIDKPMSPHKIRHSAITHFLDKSDGDIRKVQQYSRHKNVQTVLVYDDNRKDYQEQMTDLMGEDF
>NC_008312|4685402:4740814|4686644_4687367_-|WP_011612540.1|DBSCAN-SWA
MTESQTNFTKYPSFNISELEYQLESGSEKKQLQVIPNLAKIGDEGVEILMEFLQKKKLDSPTIVKGKIYQVLRQIKSSKVDEFIQKNFPLGVVPINSASNIDYSHLQVKLAHQDFLEADKLTMQKLCELVGEAAIQRKWLYFSEVDSIPIPDMKTINNMWLIYSEGKFGYSVQREIWLGSGKNWDKFLPKIGWKNGNTWSRYPNEFTWNLSAPKGHLPLSNLLRGVRMFASILSHPAWSK
>NC_008312|4685402:4740814|4699160_4699859_+|WP_011612547.1|DBSCAN-SWA
MKINTSTKIIVLFALCLGINLSINNTADARPKNRLICQIRAELCSKKESNLLCTKDDSCSQKKVESCEQDNQISCDKTQSTIQEFKPVIRPNKFSCDEGESGIPTTFVKTPQGAYPVIRWVSNYFLSAGYSPMTRCRQVSNKFQLFYDDGRLDYITTGIVNRQPVVCISSHKGGPCQGVLFTLKPNQNASKTIQKLFDIRVGATTGPLYESSSRFYLNFNDYLESLANKGME
>NC_008312|4685402:4740814|4692415_4693294_+|WP_011612544.1|DBSCAN-SWA
MFSIYILTYNEEIDIAACIKSAMLSDDIIIVDSFSSDRTIEIAQSYPVRIVQNKFKSHGQQRTWMLQEISAKYEWVYILEADERITPDLFNECLKAVQSEKYIGYYVAERVIFMGTWIRHSTQYPRYQMRLFRKDKVWFSDYGHTEREVCDGPTSFLQETYPHYTCSKGMYRWIEKHNRYSTDEASETVKQLEKGSISWKSLFLGGSEVERRRALKDFSLRLPLRPIVRFIYMYIFLRGFLDGQAGLAWCTLQAFYEYLIIIKVWEMKNMPAPSLTSAVDTNSPKLEIEAQR
>NC_008312|4685402:4740814|4726583_4726895_-|WP_011612563.1|DBSCAN-SWA
MNLNNPTTIAFEILNTVVPSLSPEKFLDALKGYFNPNLSKEENKKIMMQKIREGKLGQALADIAYYKPTSDKNFEDILEEVEEEYNKTTQEVTEKINLEDSSN
>NC_008312|4685402:4740814|4738243_4738381_-|WP_081432460.1|DBSCAN-SWA
MKPRTEGMHLVVDSTGVKVYGEGEWKTRIHGVGKRRTWRKLLECE

Homologous phage analysis in the prophage region

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_011612538.1|4685402_4685561_+|transposase	transposase	NA	NA	NA	NA
WP_011612539.1|4685892_4686351_-	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_011612540.1|4686644_4687367_-	GUN4 domain-containing protein	NA	NA	NA	NA
WP_011612541.1|4687979_4688210_-	hypothetical protein	NA	NA	NA	NA
WP_011612542.1|4688862_4689375_-	adenylyltransferase/cytidyltransferase family protein	A0A0K0KVL9	Prochlorococcus_phage	1.1e-13	46.0
WP_044136838.1|4691159_4692008_+	hypothetical protein	NA	NA	NA	NA
WP_011612544.1|4692415_4693294_+	glycosyltransferase family 2 protein	NA	NA	NA	NA
WP_011612545.1|4694428_4696336_+	1-deoxy-D-xylulose-5-phosphate synthase	NA	NA	NA	NA
WP_011612546.1|4698376_4698835_+	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_011612547.1|4699160_4699859_+	hypothetical protein	NA	NA	NA	NA
WP_011612548.1|4699865_4700720_+	trypsin-like peptidase domain-containing protein	NA	NA	NA	NA
WP_011612549.1|4702431_4703958_+|protease	serine protease	NA	NA	NA	NA
WP_011612550.1|4704794_4706996_+	Cna B-type	NA	NA	NA	NA
WP_011612551.1|4708722_4709409_-	glycerol-3-phosphate 1-O-acyltransferase PlsY	NA	NA	NA	NA
WP_063823343.1|4709745_4710915_-	DUF3086 domain-containing protein	NA	NA	NA	NA
WP_011612553.1|4711162_4711555_-	DUF3119 family protein	NA	NA	NA	NA
WP_071820691.1|4712275_4713073_-	MlaE family lipid ABC transporter permease subunit	NA	NA	NA	NA
WP_011612555.1|4713251_4713545_+	hypothetical protein	NA	NA	NA	NA
WP_076611779.1|4715751_4716598_-|transposase	IS630-like element ISTer1 family transposase	R4THZ0	Phaeocystis_globosa_virus	3.6e-09	22.7
WP_044136841.1|4717394_4717772_+	hypothetical protein	NA	NA	NA	NA
WP_044137578.1|4720767_4721199_+	Hsp20/alpha crystallin family protein	NA	NA	NA	NA
WP_011612558.1|4722058_4722535_+	Hsp20/alpha crystallin family protein	NA	NA	NA	NA
WP_011612559.1|4722703_4723204_+	Hsp20/alpha crystallin family protein	NA	NA	NA	NA
4723631:4723690	attL	NA	NA	NA	NA
WP_011612560.1|4723642_4724131_-	hypothetical protein	NA	NA	NA	NA
WP_011612562.1|4726161_4726524_-	hypothetical protein	NA	NA	NA	NA
WP_011612563.1|4726583_4726895_-	hypothetical protein	NA	NA	NA	NA
WP_081432459.1|4728609_4728720_-	hypothetical protein	NA	NA	NA	NA
WP_052845805.1|4728712_4729072_-	hypothetical protein	NA	NA	NA	NA
WP_155994444.1|4729255_4729492_-	hypothetical protein	NA	NA	NA	NA
WP_011612567.1|4731691_4734034_+	TIGR03032 family protein	F2Y1J7	Organic_Lake_phycodnavirus	3.9e-21	26.2
WP_044136842.1|4737356_4737740_+|transposase	transposase	NA	NA	NA	NA
WP_063823344.1|4737867_4738251_-|transposase	transposase	NA	NA	NA	NA
WP_081432460.1|4738243_4738381_-	hypothetical protein	Q9MCT5	Escherichia_phage	9.2e-08	65.8
WP_052845806.1|4738473_4738668_-	hypothetical protein	NA	NA	NA	NA
WP_081432461.1|4738833_4739259_+	hypothetical protein	NA	NA	NA	NA
WP_081432459.1|4739399_4739510_-	hypothetical protein	NA	NA	NA	NA
WP_052845807.1|4739502_4739862_-	hypothetical protein	NA	NA	NA	NA
WP_081432462.1|4740160_4740814_+|integrase	tyrosine-type recombinase/integrase	NA	NA	NA	NA
4745955:4746117	attR	NA	NA	NA	NA

Sequences of DBSCAN-SWA_7

Nucleotide sequences of DBSCAN-SWA_7

>NC_008312|4838317:4949144|DBSCAN-SWA
CCTAAGTAGGTTGCGGCAAAATTTCATACTGAAAAAGTTTTGGGAAATTGAATATTTGACCATCCGCAAAAAACTTAAATAGCCACTTAACTACTTTAAAAGAACTGCAAAGATGATAAAAAGTAATACTGAAATTTTTGGTTTGTAACCAAATATCTTCAACAGGATTTTGCTCCGGAGCATTGGGAGCAAATCTTGTACAATTTATCAACAATTCTTCTTCTGATAAGTATTGATTAATTGTCATTAAATATTCTCGAAATTCTTGAGAGTTATGGTAAGTTGCCCCATCCCAAAATATTGCCAATTTGTTGCCCGGTCTTTGCTTCTGCAAATATTTAATAAATTCAATAGTATTTTTAGTATTTCCACTCTCATATTCTTGCACAAGAAATTCCTTGGTTTTATAGTCTAAAGCTCCATAATAAGTCTGTCTTTCTTTTTCATTTTTAATTGCAATTTCTATTCTTTCATCTGTTTTTCCCCAAGCATAACCTAATATGTCTCCCCATAGAAGATGACATTCATCAATCATAAACACTGTAAGCTTTCCAGTTTCTATTTCTGGTTGCCATTTAGCTAAAAATTCCTCTATTTCTTTTCTTTTAACTTCTACTAATTCATCATTTTTAGCAGGATTCTTTTTTTGAGTTTTTTTCCAACTTATGCCCGCTTCTTTAAACAAGTTATAGTAACTTTGATTAGACTCAAAAACCACATCATATTGCTCCTGTAAGTAGTTTTTTAAATCTGATAACCTAAGATAATCTTGTGCTCTCAACCACTCAATTGTTTTCTCTTTTTCGACCGTTTTTAAGTAACCTTGTCTCCCTTGATACTGAAGCCTTAAACTTTCTACACCATGAAATAATGCTTGGTTTTTCCATTCACTAATAAAACTGTGAGAAACATTTAATAATTCTTTGACTTCATGGTAGGATTTTCCTGACAAGGTCATTTTTACGGCCAAGGCCCTTTTAATTTCTTTAGACTCTTTTGTTTGATTAATAAAATCATTTAGTTTATCTATAATATTCATTTTTTGTCTTTTTCTTAGATCTGTTATTCTTACTATTATATCTGTTGCGACCAATATGGGATTGCTATATCTTTTTCTTGATAACAATCTCTTATAAAATATTGTAAGTCTTTGAGTTTTATACATAAACTTTATGTGTTAAATTACCCATCTCTAAAGTTAACAGAGTTTTTCCTTTGGGTACTCTAAAGTAGACTTCTTTATAAATATCTTGATTCTTGGGAATATGTTCCATCTTTATGAAAAACACTATAATTTTGTAGTATAACTATCTTACTTCCCACAGTTGTAGCTAGCTAATTATGAAACAAGGTTAAAACTTATTTTTAGTAATTTATTATTTTATTTTAACCTTATATTTTTAGGGCTTTAATAGTATTAATTTTAGTGAATCTACCATTCCACTAATCTCCTTAATACTAATAGCTAGTGAACAGTGGCTCGTTTAAATGCTTCATCCAAAACTTCTGATAAAGTAGGATGAGTATGTACATTAAAAGATAACTCATTAACAGATTGTTTTTTAGCTATAGCATTTGCTGCTTCTTGAATTAAGTCAGAGGCATGAAGACCAATAATATGTACTCCTAATAATTCTCCTGTATCTTGACGATAAATTACTTTAGCAATACCATCTGTTTCATCTTCAGCTATCGCCTTAGAATTACCCTTAAAATAAGTTCTGACACTTGCCACTTCAAACCCCTGTTTTTGGCCTAAATCTTTTGCTGCTGGTTCTGTCATACCAACATAGCTAATTTCTGGATGAGTAAAAGCTGCCGCCGGAATACTAAGATAATCTGGTTCTCGATCACGACCACATATATTTTCTACCACTGTTATTCCTTGGGCAGATGCTGCATGAGCCAACATCATTTTTCCTGTTGCATCACCAATTGCCCATAAATTAGGTACTGGTTCACCACTTGACAAAACTGCCATTTTGCTATTTACTGGAATAAATCCATATTTATCAGTTTCTACTGCTACAGAATCTAGTCCTAAATCTTTTGTATAGGGAATGCGACCTGTGGCAACTAGACAAGCATCAACCTCTATAATTTCTTCTACTTCTTTAGTCTTGGCATCGGCAAGTTCAATAATTACCGGAGATCCAGGAACTACCTTTATAGCCAACTTCCCTACTTTTACTTCAATATCTCTTGACTGAATTAGAACTCTTTGTGCAATCTTAGCTATATCTGGATCGAAAGTAGGCATTAACTTATCTAATGCCTCAATCATCGTAATTTCAGATCCAAGGGCAGTGTAAATATCAGAAAATTCTAGTCCTATATAACCACTACCAATAATTGCAACCCAAGGTGGTAACCAGTCTAGTTTAAGAGCATCATCACTGGTAAATACTGTTTTACCATCCAATTCTATTCCAGGAGGAACAAAAGGTACTGAACCAGGAGCAAGTATAATATCTTTGGCAGTAAAGTTTTCTTCTCCCTTTTCCGTCTTAACCGTAACTTTTTGTTTTCCTGCTACCTGAGCCCACCCTGTAATAATATCTACACTCAGACGTTTAAGGCTTTTGCTCATGTCACCTCTAATTTTGGTCACAATGTTACTTGCATGAGTGGCCATTACTTGTCTGTCATAAGAAACATTATCCAACTCAATTCCCAAAGTTTTTAAGTGGTGAGCATTTCGTAACTCTCGAACTTTACCTGATGCTGCGAGAAGTGCCTTAGATGGTATACAACCTCGGTTAACACAAGTACCTCCCATTTCTGCTACTTCTACAATAGCTGTTTTTAGGCCACAACTGGTAGCGTGTAATGCTGCACCATGTCCACCGACACCTGCACCAATAATTATTAAGTCGTAATCAAATTCTTGAGTCATTTCTGTTTTCTAAAACTTCTAGGTATGTTTGCAAAAACTATATTTTTTTGGTTTCTTAGGAATGCAGCTAAATATTATTAGAGTTTTATTTGACTCACAGGACTTACATAGAATATTAGAACACGAACTATCTGTAAGTATTAAAGCTATTACCTTCGACTAGATTAGATAAAGTGCTTCTACGTAAGTCCTAACTAATTTTGCCTACATTCCACAAACCAACTTGGTTTTAAATCACAATCAATCAGAATATAGAACCCATTTAGAAACTCCTTGCATAATCATCATCTAAAAAGTTTCTTGGTTTAATCATTATTGCCATAGTTATATTTCATATTCAGCCATTGGCCACAATTGGCCATTAATTGGTACACTAATTACTTCAGCTTAAATAATATACCAAATAGGTCACATATATCATTTTTATAGATACCTTAGCTTTGTAACTACTTCCAATACTGATAACTTATAATACAATAAAGTAAAAATTAATTTAATCTTAAATTTATATCTTAGAATAAGACTGGCAAAATTGTATTCCCTTGATATTTAGTAGTTAAATAATGTTATCACAGTTATGTAGAAAATTAATTTAACATGATAGTGAATATATGGAATAGAAAAAAACTTTTACTGGAAACCGAAAATTTTATCTATACAAGTATTAATTATCAAAACTTTGTAGTGTAGGCATATTGCTTGATATTGATGTACTGTTATGAAAATTATCTGTCTTCTTGTACAAAGAATAGATGAATTTTTATTTTTGCTACTATAAATATAAACTCTTATTAGTAAATTACCTTAATCTGACTAAAGTTATGGCAAAAATTGATAAAATCGACAAGGATAATCTAGATCTATATTTTAGAAATTAAGTTATATAGAATTTTCAAATGATATATGAAAAAGCATCATACTTTTCTAGATTCATAAAAATGAAAAGCTTAAACTTAACTAAAAGCTTATATAAACCGTTAATAATCTTATTCTTTTTACTTTTTGATGACATCTTATCAATATTTTTTTAGTTGTCAAAAAAATCTGCATCAATCAGATTTTATTCCAGAGAATGAAAAGCAAATAGTTCATATATCACTTGCCACTCTTCCTCTATTAAAATTTGATTCACACAGCTAAATAATTCAAGTATTTCTTTTCTTTTAAGATAGGTTAAAAATACCAAATAATTAGTATTTGTTTTTCTTTAATCTTGTGATTTTTCCCTTCTTTGTCATTGATTATGATTAGCTATTTCACAAAAATAACTGTATTTTCTACATTACTTACTGTATATTTTCACTATTCAATCTAGATCTCATAAATTCAATCTACCAAAATAGTAATCTATTGACAATTTGTTAATTATTAATTGGTATTTTTAGTTGATTTTTACTATCTCCCCATCTGATATCAAAATCAACCTCATTATTTGCATAAACTGCAATCTTTCCATCTTGTATTTATTCTATAATTATTTCTAATTTTGACTAGATTTTCTCAAGCTATGTTGAATTTTACAACAAAAATTTTCAAATTTAACTAACTCTATATAAGTAGATTTTTATCTCAACCATATTATTTTTTAGCAACTAATATACATAAATAATTTCCTAACATATATAGGTTTAAATATAACGAATTTCATCTAATATCATCCCCAATGATTTTGGGGAATTTATATGATTTGTAAAATCAAATAAGCGATTAAAACACTATAGATATGAATGGAAATACTATTCTCATTCTTAGTCATTAATATGTCTGATTTTAAGTAAATTTTTAAATTTTTTACCAGTAATTATATCTGTTATCTTTGTACATAAATCTCGGCTATTTCTTTATTGCTTACTTATTCTTCTCTATCGAAAGGTAAATTAGTAGTTAACCTAAATTTTGTTCTCTTTTATAATACTAATTCTCTATGAAGCTGTGCTTAATATAGGTTAATAAGATATAATAACAAAAAAACTAATTAGTGAGCAAACTACGTGACCTTTCGCGATCGCTGTTAGTCAAGTATTTATGGCCCTTCCCTTCAAAGTCAAAATTAATGAAACACTTTCTGAACTTGAAAAGTGTTTAAGTAAATCAATAACAGCTAAAGGAAAAGAACGAATACAAATGATTTATTGGCTCAAAACCAATCTAGTATCAACTCGCCGAGAACAAGCCTTGCTGCTAAGTCGTTATGAATCAATGATTACACGTTGGCTCATAAATTCTTGAATTGAAGAACTACAAAAGCTTTTAAAACTCAAAAATGCACCAGGAAAAGCTTCAAAAATTTTGGGAGAGGTTTTAACAGGCTTACAATAAAAATTGTCAGAGCCAGTTGGATTAAAAAGTTTAGGATAAATTTATTGCTGGTTACCAGAGAAATATCAAATTAAAATAGCTGATAATAACGTTTATAAAATTGTCAAATATAAGGAGTGGAACTAAACTTGAAACACCTTGTATTTATAGTATTAATAAGGGTATTTTAGCTGTATAGAAAAATTTTAAAAAAACTAAAACAAACCTAATTTATACGAAATAAAATACGCTAAAGGTATTGATTTATAAGAGTTTCACTAATTTACAAAAAATAAATAATTTTCAACAAGTAATATTTATTTATAACGAGTGAGATGTCACAATAAAACAAAGTAAATTTTGCTTAAATAATATTAAATATTTTTAAATTATTTAGCATTATTTATGATTATTTTTTTATAAATTTTTCAAAGTATAAATGTTGTTAATTGTAAAAAATATAATTATGCAATTGAGTCAATTTTTTTGGTAATATCAATTATTTTTATGTTTAATTTTTAAGAAAGTATTAACTGTAATTCAATAAAAAGTTGTCAAGTTAAAAATATCAAAAAAAATCGCTTATACTTCAGTAAGATTATGACAATAATAATTGATTTTATTAGTCTAGTCATCGTAATTTTTAAGCTTATATTATTATCAATCAAAAATTATCAAATATCATCAAAAGTATTTTCATTATTTGTTTATTTATAATCGTTTTATCGAATTAATTATATTAAAATTAATGCTTGTTATAAAGTTACCTTAATATACAAAAACGTGACTGCAAATATTTTTTATTAATAGTATAGGAATTAAAATTTGTCATAATAAAGGATCCAAAAGAAATAAAGTATTTAATGGATTAGGAAAATGGGTTAAAAGTACAGTAGATTGGTATCTTGGATTTAAGTTGGACTTAATCATTAATTAACTTGGAAAAATATTAGCTTTTCAAATAACACTAGATAAGGTAGACGAGGGGAAATCAGTTTACTTTTTATCTCAAAATTTATAGGGAAAGTTATTTTGAAATAAAGGTTATATTTATCAAATAATTTTTGATAAATTATACGTCAATAATCTAAAGTTAGTGACTTTGTATTATCAGAAAAATATAAACAATAAATTAGTAAATTTATGAAATAAATTAATGTGTACGAAAACGTTAATTAATTAAAACTTTCAATGACCAATTAAAAAATATTTCACAGCTTGTTCACTCTCAATATTGAAGTGTGTATAATTTTATTGTGAATATAATTATAGGGTTAATTACTTATAGTTTAAAATATCAAAAAACAGCAATTAAATTAGATAAAAATGAATAAAAAAGTCACTATTTTTATACACTCAAGCGGCATTAAATAACATTTAATAAAGAATTAAAAAGTTTAATTGATGACCAAAGGTTAAATATTTTAGATATTTTTTACTTGTCTAGTTATTATCAATAAGCATAAGTAATTTATTATTTTTGATTCTGTTTACTTTTTGTCCTTTTTATTTATATATAACTTAGGTGTAATTAGGATTAAAAGTCTTATATAAACTATTTAGAAAAAGGAAAAAATTTTGCTACTTTTGTCAAGATGAAAGCTACTATAGGACTCAAAAAAACAAGCAAAATGATAACTTTGCACATGAGTTAAACCATTATGATGTAACCAATGACAACGAAAAAAAAATTACCTTTATAGGGCAATAGAAGTCAAAACTGGACACAGCTATTTTTACAAATTTTTTCCAACATGACGGTAAATGTTTTCAGACATTTATCAACCAATTATCTGAAAAATTTAATGAGAGTATCATTTTCAATTTTCTTGGCAATGAGAGTTTTTAGCAAAATATAGAAATTCCTGAAAACTTCCATACCAATATTCCCACGTCCTCACAGTTGCGGAATTTAAACCTATTGAAAGTTTTTTGCAACAATTGAAGCAAGAACTATAATGGAATGATTACCCAAATCTTCAAAAATTACAATACAAAGTTTCCTAGATTCTCTTTCCTGAAAACAGATGGGTTAAAATTGACATCTTTGATTAGACGAGACTATTTAATAGAAGGACTATTATGTGTAACTTCATAGAGAATTAATATTAGCGATCGCTCTTTGGAAGTTCTTTCTATTGCTAATTGACTTTCTTCACTATTACATCTTGTTAGTTTATATTAAGCACAGCTTCATAGATAATTAGTATAAAAACTTTTTTGACATAGATAAATATATTTAGACAGATAAGAAACACCAAACACTACCTATCTGCAAATTAAACCATAAAAACAGACTACTTTAATTCAAGTTGACGTTGACGTTGAATCTCATACAAAATTATAGCTGCACTTACAGCAACATTCAAAGATTCTACTCCATTACTCAAAGGAATTTTCACAGAATAATCAGCTAAATCAATTAAATCTTTAGAAATACCAGAACCCTCATTTCCCAAAACTATTATTGTAGGTTTTCGTAAGTCTATTTCCCAATAGTTAATATTTGAATTTGGAACAGTCGCTAAAACTTGTAGACCTTGACTTTGTAATTTTAATATTTCATTCTTTAGGTTTTCAGATATTGCCTTATGTAAATTAAACCATTCCCCAGCTGACGCCCGAACTACTTTAGGATGAGACAAGTCTACACTATCTCTACTTACGAATAAACCATCTATATTTGTTGCTACAGCTGTCCTAATTATAGTTCCCAAATTACCAGGGTCTTGAATTTTATCTAAAACAATTCCCAAAGTCGTAATCTTCAAAAAATTTGTCTGACTCTGTGGTGCTATAGCCACTACTCCATCAGGACTAACTGTAGTAGCAAGGGATTGAATAATCTTGGTACTTACTAATTCTATCCTTTGAGCTTTTTGAGATACTAATTCATACAAAAATTTATGTTTTTCTTGCCATTCAAATGTATGGCAGACAGTTATAAGAGGATAATTTCTCTTGCAAGCTTCTTCCAGGAGATGAGTTCCTTCAACTAGAAATAATTGCTGTTCCTGCCTCCCTTTTGATTGGTGAAGTTGGCGAATTTGCTTTACCAAAGAATTCTGTAAACTAGTCAACACTGTTGATCTTTTATCCCTTATTTAGCATTTCTATCTTATAAGTGAAAGAAGCTCGGGATACTTCTTATTAATAAAAAGTTCCGGAGATATTATCCAGTTTTTCTGATGCTTTTTTCTATTTCCCTTTTTTCTAGCTATTAGGTTTTTACAACTCATTTTATTTCCCTTTAAAACACCTAGATTAAACTTTGTTTTAACTAAACTTTAGTTTAGGTATTTTTTGTCTTTTTAGGTGGAGACCTCTCTCAAAATAATAATCAAAGATTGATTAAGAGGTATGCGGAACCCGGGACTTGAACCCGGAAGTCCTTGCGAACACTAGAACCTGAATCTAGCGCGTCTACCAATTCCGCCAGTTCCGCTTGCAGCACGAATTTTAATTATCGCTTATCTATTTAAACTTGTCAATTACTTTGAATTAACTTTTTGATCATAAAATAATTAAGATTTTTTATAATGAAAATTTATACTTTTATAGATTATGTTTGTAATTTTAAATATATAAAATTGTTATATAAGTTAATAAAAAACAGATTATTGAGAATATTCTCATTTATTTCTACCTATTTACGTTATTTGAAAGATTTGGTATAATCCTGAACATTAATGTATAATCTCGCAGAGCGTTTTAACTTAATTTAAATTAAACATCTATAAACTCCTTTATACCGTTAACTTCAACTACATAATAGCTATTTCTAACATTTGAAAGAGTTTTTTTAGTTAATAAAGCTTAACAAATTTATCAACAGTATTTGACAAAATAAATATTTTCTGGTATACAACATGACAAATTGTATATTAATTTCAATTTCAGCACTTTTATTCTTAATACATCCATAATTTTTTCAATTTTATTCAACTAAGAATTTTTTCTAACTATGATGGTCTTATTATCAAAACTCTCAGTAGGAAAATTCATAATTGTCTATGCTACGGTAATGTTAAGGGACTCAAAAAGGACAAAAATATACTTGAATCCAAATTTAGGAAGATATAAACTACCCTGAACCAAAGAGAAAATAATGTCTTTGGATAGATAAATCTATGCTTAGATGGAAAAACTCAAACCTTTGTCAACCGACTAAAAGGCAGAGGAAAGTCTCGCAGTGATGTAGGGCTTTCTATCATTTCGCTTTGCAGAAGATGTCAATTATTGGTTAATTAAACTGGCTAGTTTAAATCAGGAAATACTTCTCGGAGAGCAGGGTGAACCAAAACATGGTTTTTAACATTCAATCCCTTAGCCAACCCTGGATTCATATCTAAAGCTTTACTACCATAGTTAGCTAACTGCAATACATAAGGTAAAGTACTATTATTTAAAGCTTGAGTAGCTGTCCAGGGAACTGCTCCAGGCATATTAGGTACTCCATAATGTACGACACCTAATTCCTGATAGATAGGATTTGTATGAGAAGTAGGACGTAGAGTTTCCACACAACCACCTTGATCCACAGCAACATCGATAATTACAGATCCAGAATGCATCTGCTCCACCAAACTTTTGGGAACTAAAACTGGAGAACGACGGCCAGGAACTAAAACTGCCCCTACAAGTAAATCACAATCTGCGACTGCTGCTTCTATAGCAGAGGAACTACTATATAGTAACTCTAACCTTGAGCCAAATACAGTCTCTAAATAAGCCAACCTTTCCAAATTAATATCCAAAATTTTGACTTTTGCACCCAAGCCAACAGCAATTTTAGCTGCTTCTGTACCAACTATTCCTCCTCCCAGAATTACAACTTTGCCAGGGGTAACACCAGGGACCCCACCCAAGAGAACACCTCTACCACCTTGTTGTCTTTCCAAAAATCTTGCCCCAAACTGCACAGACAAACGACCAGCTATTATACTCATAGGAGTTAATAAAGGTAGCCTTTGGTCAGATAACTCTACCGTTTCATAGGCGATGGCCGTGACGCCACTTTCAATTAATTTTTTAGTTAACTTCCGATCCGCAGCTAAATGTAAATAAGTAAATAGCAGTTGTTCTGATTTGAGAAATTCATACTCTGAGGATAGAGGTTCCTTAACCTTAACTATCATGTCACACTTCCAAACGTCCCTGGTATCTGATAAGATATGCCCGCCTGCATTAAGATAGTCACTATCACTAAAACCTGCGCCCCAACCAGCTTCTGTCTCTATAAATACTTCATTACCTGCTTCAGTACAGACCTTAACACTTGCAGGGGTTAATCCTACACGAAACTCCTGATCCTTAATTTCTTTTGGAATACCTATTTTCATTCCCTATCTCCATTTATGTACCAAGGAACTATGTCTTTGACCAAAAAATCATGTCTGAGTAAATATCTGGTCTAATTAGCTTAAATGATAACAATTTGTTAATTGACCTTCAAAGATAACTGATAAATTTCCCTGAAACCCTGACTATGGGTATTAAAATTTCCCAGTTATCTCGGTGCCTTGATATCCCTGTGGTTTTGTTCGCAATTAATTAGGGAAAAGGTTCACGACTAAAATGGGCAAAAGCTACTCTAACTTTTATCTTTTCTTGACTAACTTTAGAGAATGAAATATCCCTGCTCTTTTAAGAAGGCTAAAAAACATTTGCTGTACACCTACCTATTTAAGGTTATAACTTTAGTCAGACAGAAGTACTTATAACTAATATAGTTGTTTTAATTAAGATTGAGACAAAAATTAAGTAGAATAATTTTAAGTCAATTATAAAATATTTCTAACCATGCTTTACAGTTTAGACTTCAGACAAAAAGTAATAAATTTTGTAGAAAATGGTGGTATGCTTACCAAAGTTACTCATGTATTTGGTATAGCAAGAGCTTCGATATATAGATGGTTATCTCGCCCAAAATTGGAAGCAACTAAGGTAAAATGTCGTCTAATAAAATTAGATTGGAAAGAATTATAAAAAGATGTCAAACTAAATTCAGAGTGTAAATTGGCCGACAGAGCTAAAAAAATTGGAGTTAATCCTACAGCTATATTTTATACTTTGAAAAGAATGAATTTTCCTTGAAAAAAAACTTCGTTATAGGTAAAGAAATAGAGAAGAAAGAATAAAATATTATCAGAAACTACGAATTTTTTTTGATGAAATTTGGAAGTAAAAACCTTGTATTTATTTATAAATCATGATTTGAAGATAATCAAGACTGTATTTATACCTGGTCAAAAAAAGGGAAAAAAGTTTATGTTGAGCAAGAGAGAAAACGAGGTAAAAGAGAAAATTGAGTAGCTGGGAGAAGAAAAAAGGAAAAAGATTTAATAGCACCAATTATATTGAAAGGAACCCTAAATGCCGTGGTATTTTAACAATGGCTAGAGCAACATTTATTACCATCGTTAAAAATTCCCAGTATACTGCTGCACGGAGAATTAACCAATTCATAGAAAAAAGGTTATTAGAGAATTAGTAGAAGCAGGGGATTATCAATTACTATTTTTGCCAAAATACTATCCTGATTTAAATGACTAAGAACATGATTTTAGTGCATTAAAAAGACTTAGAATTTATTCACCTATCAATACATCATTTTTTTATATTTATCGCTGCGTTTACATAAATTTATATTACTATACCGCAGTGTGGAAAATTTGGGAGTTCTTTTGGATAATTCTTTGGGGACTTTTTCACCATAATTTGAGAATCAAAAAAATCCAAAATAATATTCTTAATCAATGGAACTCAATGGGACATTGATTGACCGTCGATTTAGCTCACTCAAAGTCAATTAAACTATAGGTTAATAAGGTAAAAGTCTTTAACCTTAAAATCCCTACAATTTTTCTGGAGCTATCTAAATTTTTTTGGTAACTGATAATTTAGATGAAGAAAAAGAATTTGTCGACCCCTAGACATTTGCTGACTTTCCAGTACAATCAAGAGCAAAAATGAAAATCAATAACTTATGCCATTGAGGGAGGATAGAGCCATCAACCAACAATTACATTCAATAGCAGACACCGATAAGCTAAAGTCATCTCCTGTGAATCAGTCAATACTGAAAATTTGGGGTCCTTCTCGTTTAAAAGGAAATATTAGTATTAGTGGTGCTAAAAATTCAGCGCTCCCTGCAATGGCAGCAACACTACTTTCTTCAGGTGTTTGTCGTTTGCGTCAAGTTCCATGTCTAGCAGATATTAACATAATGGGACAAGTTTTATCTGCATTAGGAGCAAGAATAAAACATAATACTAATACTTTTACTTTAGATATAGATGCAAGTATTATTAATCATCATGAAGCTCCTTATGAGTTAGTTAGACAGTTGCGTGCTAGCTTTTTTGCCATAGGTCCTATTTTGGCTAGACTAGGGGTGGCTCGCGTACCACTACCTGGTGGATGTGCTATTGGTGCAAGACCTGTTGACCTTCATGTTAGAGGTTTACAAGCTCTAGGAGCAGAAGTTCATATTGAACATGGTATGGTTAATGCTAATATCAGTGGTAGTAAAAAGAGGTTACAAGGGGCAAAAATTTATCTTGACTATCCCAGTGTTGGAGCCACTGAAACTTTAATGATGGCAGCTACCTTGGCTGAAGGAGAAACTATCATTGAAAATGCAGCTAAGGAACCAGAAGTAGAAGACTTGGCTAATCTATGTATAGCTATGGGGGCTAATATTTTCGGTGCAGGTACAAAAAGGATAGTAATATCTGGAGTACCAAAACTACACTCAGTAGATTATACTATTATTCCTGATAGGATAGAAGCTGGTACATTCTTAATAGCTGGCGCGATAACTAATTCAGATATAAGTATTTCACCAGTAGTGCCTAAACATTTGAGTGCAGTTATTTCTAAACTTCAGTCGGTAGGTGTAAAAGTTATACAGGAAACATCTGATAGTTTACGTCTTTTACCTAGTGAAATATTGAAATCTACTAATATTAAAACTCAACCATATCCTGGTTTTCCTACAGATATGCAGGCTCCATTTATGGCTTTGCTTAGTGTCTGTTCTGGCACTAGTGATGTTACAGAAACAGTATTTGAGAATCGTATGCGCCATGTTTCAGAATTAAATAGAATGGGTGCTAATATTAGGGTTAAAGGAAATCATGCTATTGTTAAAGGTGTACCTAAGTTATCTGCTGCTCCAATTATTGGTACTGACCTTAGAGCTTCTGCTGCCTTGATATTAGCAGCGCTAGCAGCAGAAGGGGAAACAACTTTTCAGGGTCTACAACACCTTGATCGAGGCTACGAACAACTAGAAATTAAATTGCAAAAGTTAGGAGCAAAATTCGAAAGAGTGGACTTAGTTGAAGAAAATGAGATTTTCCAAGCTTCTATCTAATAAAAATCTGATTACACTCTAGTAAAAGTAGAAGCTATCAGAGATTTTGTTTGTTTATTGGAGAACAGATGTATTCAAAACAATAACTAAAAAGTTGTCTTTTTATGAGTGAGGCTCTAAACCAAATTTTTCGGTAAATGGTTTGAATATATACACTTCCTACGGCCCGTGAGGTAAATATCTAGCGGGCAATATGCTTATACTACAAAAATTTTATCTTTAACGCCTTGTAGATCATTTGGATAATCTGATCCTGTCTTTTCAAAGGTCATAAAAGATGTTAATAGACCTCTGAGAAAAGTCTGAATTTGAAGTATCTTATGGTTGACAAATCAGATATTGTCCTACTTTAAAGAGCTATTTGTAGCTAAATAATAATCAGTACTTATAGAATTTCAAAGAGCTAATGGAGTAGGGTTTGTTTCTTTCACGATTACCAACCAACAGTGATTTTATTATTTTTTGCTGATTTAGTTCTGGGCATAGCTTTTGTAAGTACTTTATGCTTCGATTATATCTTTTCTATACGTTTGCAAGGAGGTAAACTTTTATATAATACAGCAGTTTCTGAAGCTATGAGTTGCACTTATAGTTAAGAATTTGATGATATAAATATGAATTCATATCCAAAAGAACTTATCAGAAAAAATAGTTGCGACACATCTGAAACAGAAAATATTAATTCCCATTTGTAGCCATCATATTTTCTGTTATTAAAGGTTTAGTCCAGAAACTAATAAAATAACACAAAACAGATGTAAATTTAGAACTATTAAAATGTGGTTAATCAAGGTTTAGTCATCTGATATGCTACAGATTTAGATTTCCAACAACTTGTGTCAGAAAATCCAGATGCAACTATCGCAGAATTATATGAAGTATTTTAACCTTTTAATAAGAAATTGGTTAAGTTGTACTGGTATATTTCGAGCTTGACAAAAATTATGATTAAGTCGTAAAAAAAATGCAGCGTAGTAGTTCTAGTCGGAACAGAAAGAGTACAAAAATTAAGAGAAGAATATAAAGAAATTAGTGAAAAATATACACCCAGAAAATTTAGTATTTATAGATGGAATAGGTGTAATATTAGGTTCAACCAAAACTCATCCATGCTTACTCGCTTTGGGGATAATGGGTTAATTAAATGAAGTCATTTTATCTCCCTCAGAAAGTTACAGTAATTAGTGCAATAAGTATTAAATAAGTAGTAGGGTTAATGACAATAAATAATTCAATGGCAAGTATTGCATTTAAAGTATTTATTGAACGTTTTTGACTACCATATTTATAGTTAGGAGCGGTATTTTTGATGGATAATTTACCTGCACATAAACTAGCATTAATTGAACATAGAATAAAATCTGTAGGAGGGAAAATTATAAATTTATCCCCATATTTCTCAAACTTTAATTTTTAAGAAGTTATGATGGTCACAATTGAAATATTTTGTACGAATTTTTTCTCCAACAGTACACAAAAATGGTTGATATAGTCACCTGGGGTAGTACTTTAGTTAATATAATTCTCAACATTTAAAAAACTGCTTTACTAAGTGCTGTTATTGTACCTCATCGGCAACGGAAAGTGCTGTAAATTCTTTTCTTTAAGGGTGGGTTTTAGGGGTCTTGTCTGTGGTAAAAATACTAGAATTATAGTCAAAAGTAAAGGAAATTAGGCTATTTTACACAATAATTTAGATAGTAATTAGACAATAATTTTAGCCAAGGATAACTATTTATCATAAGTTTCTACCCTTTATTTCCTCTGTCTATACCGTGACATTTTTAGCACTAGCTAAATATAAATTTTCCTCTTTAGTTATTAATCTTAATTAAGCTTTTTGTTGGTGATACTTATGCTATTTTTATGCTAGTTTTTTGTTGTTTAAGTACCGCCATTCTGTGCTGTAATTATCTATTTCTACTTCTATTACTACACCTCTATATTAAGCCTATTATCTGTTAATAAGTCACTCATTAAAACATGAAAATAAATCATGTCGTCTGTGTGTACGTTAAAGCAGTCCTCTTTAGCTAGCATATCCAGTTCGGTTTTTTTTTAAGGTTATATTCCTAAATATTTTAATCTGGTTTCTTACTTTATTTATCAAGGTTCTTTGTATGTTATTATTATCAATTTGAGTATTATCACTTAAGATAAGTTTTAAGCTCAGAAATGGTATTGAAGCGATTCATTCTAACTCCTGACTATTGTAATTTGCAAATCTGAAAGTCCCCGAAATGTCTCCTAAAAAATCCCCTAGCTATTTGTAGAAAAAATTTGTAGCAAAAATTTATAAAATTAGTTTTATTTATGTAAAATTGATATTTTGGTATTACATTTTGGTATTAGTTATAAGCATAAAAAAGAAAGTAGGAAGATTCCATGGAATCTTCTTACAGAGGTTTGATAAAAGCTTGATTTACTCTTTTTTACATTAATACAGTTTGTTCAGTATTATCAGTCTCAGTTTTATTGACTTGAAATCTATCAGTATCATTTAATTCTATTTCTACCCTTCGCAACTGTGGAGTACGATAAGCAACTAATACCGCTCCAATATTCAATAAACCCATCAATACAAATAATAAAGCTATTCCTCTACCATCTCCAACCCCAATAATTCTTCCTACACTACTTGCCAAAATTCCATTTTCACTCATCAAAGGTTTAAACATAAACTCTACTAAAGGTGCCGCGCTTAGATGAGTAATTACTAACAAAAACTTTTCCATCATATTCTGCAAAGAAAAAACTCGCCCTTGTAAATATTGAGGTACTTTCTGTTGCCAAATAGTATGATTTAAACTAACAACAATTGCTCTAGAACATAAATAGCCAAATCCTCCAATAGCAGCCAAAATTACAGCGGGTTTTAATCCTCCTAAACATAGACATAGTCCTTGGATAAATACAAAAACTAAAATACCTTCTATCCTACGTTTAGAACATCCCCATAAACTTACTATAACACTTCCTAATAACATTCCAATGCCACTAACAGACATTACTATTCCTAGTTCTTTTTCCGAAGCAAAGCTTAATACCATTGGCAAGAATAAAACTTGCAATATTCCCGCACTTAGATAAATAACTCCAAAGAAAATAGTCAATTGGCGTAAACCAGTACGGACGACTACATAATTCCATCCTGAAATAACTTCCTGCCATAACTTTTCAATACTTACTTTTCGTCTAATCTTTTGCTGCTGACTTATGGGGAATTTGACACTTAACAGAGTAAAAAATGCCAGTAGATAGGTACTAAAATCGATTAATAATATGCCGTGAAGATGAATTTTGATGATCAACACACCAGCTATACTTGGGCCAAGAATTCTTGCTGTTGCTATTGCACCTTGTACCATGCCATTTGCCCGACTCAAATGTTTTGGAGGTACAAGTTGGGGGATTACAGATATATAAGCTGGCCATTGAAAAGCGTTACAGACAGAACTAATACCCACTGCTATATAGATATGCCAAACTTGTAGTTGTTGGGAGAATACTAAGAACATTATTGCTAATGCTGTTACTCCAGTGATTGAGTCGCTGACAATCATTGCTTGACGACGACTCCAGCGGTCTACCATTGCACCAGCAAATGGTGAAATAAAGATACTAGGTAGATGAATGAATAAAGACAACAGAGCATAGTGGGTAATTGAACCTGTTGTTTGATATACCCATACTGCTAGAGCAAATTCACTCAGACTAGAACCTAATAGAGAAAAAACTTGACCCAACCATATAAATACGAATGTTTGCATAACTTTAAGTTCTTAGATGAATCATATATAGAGTCGAATGGCATTTGTTGAGTTTGCTCGATAATACTTAATTATAGTTTGATTATGGTGATTTTAAAACACTCAATATTTATTAACCTAGGTATTTAAGCCCTAATATTTTTTTGTCTCTTGAACTTATTGATAAATGCTCAGGCTATTAGCTATTAAATTAATTTCATTTTTGTCAGATAGTTTGTCAGATATAACTAATATTATTATAGTTATTTAATAAATTTACTCTGTTAAATTAGTCACTTAAAAGTTATAAGGCTGAAAAACTAAAAAGTACTTTTATTTACTCTAACTGTATCTTCATAGAAATAAAGCAAAGATTAAATTATCTTAATATTTTTATAATTTATTTTTATCGAAAATTTTCTCTAATACTATTCCTGAAAGGAACCCAAGAAGTATTGTTGCAAATGAGACAAAAAAAATATATAAAATCAAGTAAGGTTTTGAATCTATAATTGATAGAAAAATAATCTGAATGTTGTTATTATTTAGATAGCTATAATTTTTTTTGACATTTTCTTGAGCACTTAAAATAGAAGTAATCGTATATTTTTAGCTAAAATTGTCAAGCACTTTTTTGATATAATTAAGTAAACTTTTTTCCAACTTTCGAGTATCATCAAATTTAATTCATTCATACTTAATAAATTTCCAGTAGTTTCTACTTCATATTTTCCTTCCTATCAGAAAGAAAAAGGAAGATTAAGATGATAAATTTATTTACTAGTATATTAAGAGAGTATCAAAGATAGCTATTCTTCTACTAGTATTGAATCTTCTATACTATATTTTATAGCAATTCCCAAAAATAATCTTATACTTACTTAAAACTTCAAAAGATTAATAAAGAAGTAAGACCAATATTTTTAACACTTTTTTTTTACAACGCGCAAAGATATCTTAATACCTAGGAACTCTAGATGCTATATCCATTATATGGAAACTCCCAAGCATCTCTTAATAAGATTTAGGAATACTTTTAATTTTGGTATTTATTTATTAGTTAGGAATCAAGATTTTTAGCATAATTAAACCTTAAATATTTTTTTGATAAATAGTTTCTTAAATTACAGATAAATCTTTATATTACTAGCAGAACGAATCCAATAAACCAAACCCTAGCTTATTATTTGTCACATCCAGATGGATAACCCTTAGTCTTATTTAGCCGTCAGGTCTTAACTGATAAGTTTATGCAAGTAAATACCAAGTTTACCTGATAATTACATGACAAACACTCCTAATATTCCTAACATTTTAGTACGGTGCGGTTCAAAGGCAATGGGAAGCAAAGTTTGCTGTACAAACATAACTTTTTCATTCTCTTTGGAGACTAATTACTTCTTTCAATAGAATGAGTTAATAACTGATAACTGATAACTGATAACTGATAGTTAATAGCCGAAAGCTGAATGCTTATGATTGGAGTATAATTTGCTCTTGCCAAATTTTAACTAAGTTAGCTACTGCATTATCCCAACTATATTTTGAAATAGTTTCCCTGCCATTAATACCCATTTCTTTCCGTAAATTACTATCTTCAATTAAGAGCTTCAATTTATCACAAAAACTTTCCTGATTTCCTGGTGTAAATAATAAGCCATTTCTACCATTTTGAATATTTTCTGTAACTCCTCCTGCTTCAGGAGCAACTACTGGAATACCTGCTGCAAATGCTTCTAATACAGTTAAACCTCTAGTTTCTTTTTCTGAAGCTGTGACATGAAAATTACTATTTTTTAAAATATTAGGTATATGTTTGGGAGATATTCTACCTAATAAATAAACATGATTTGTTACTTGAGATAACCTGTTTGATATTTCCTCACGCATCGGACCATCCCCAACAATTATTATGGCAACATTTTCTATATTTACTAATTGTTGAAGTTTTACAAAAGCACCTAAGGTAAATTTCCAGCCCTTATCTTCGGTTAATCTACCTAAAAATACTATTTTTACTTTGTTGTTTAAGTTAGGAATTTGATAATTTAGTTCCCAAAAATTGGTTGTTATTGTAGCTGAATTAAATTTTTCTATATCAAAACCATGAAAGTTGATATACATAGCATTTTTGATACCCATGCCAATAATTTTTTGATGGGTTATAGTACTAGAAACTAAAGTCAAATCGTATTTGTTGTAAATTGAAACAAAACTTTTTTCAAAGATTAACTGTAACATTAGGTTAATGCCTTTTGGTAAAGGCAAAAAATCTTCAAAATATTCTAAAAAGTTAGTTCTGAAAGTACAAATACAGGGAATATTGTTTTCTCTAGCAAATTTGATTCCAGCTAAACGAAAAAAAGCAAAAAATAATCTTTCTGGTTCATCTACATGAATAATATCTGGTTGAAACTTTTCTAGCTCTCGAACAACTATTTTATAAGTATTAAATCCCACATTCCTTTCAAAATCTAGAAATGGTGTACTAGGTAAGTTAATGACTTGAATTCCTGGGAAAATATTACCAGTATAATCCTTCCAATTGGGATATAAGTGAGCAAGGGGACTATAGTCTGGGCAAAATAATAAAACTTGATGTCCGAATTGACTAAGTTTTTGAACTCGGTAATAACCACTGACGGTTACTCCATCTAATACAGGTAAAAATCCAGAGGCAATAATAGCAATTTTCATAAACATAAATAAAGGAAAAATAAATAAAAAAGAAGGCAATAAATCTAAGGTTTCAGTTAATTTAAGTCATTATTAATAAGCCTAATTATGAGTGCTAATTTTTCTAAAAATAAAAACTTAACTTATTTTGTAGGATTTTTATTAATATATATAGAAAATAGTATACTACAATTAGAAAGAATAACAAGCTTTTAACTATAAATTTTTACCTTATAATGATTAGTTAAGGAGGTAATAAAAAAGTCTTTTTGCATTCATTTTTTTTTAATTTATAATTGCGCTTCATAAACTTACAAAATAAAGGTTTAAAATTTGGGAATAAAACGATTTATATGATTAATATTCTGTTAAAATAACTCGTAATCAGTAATAATATTTTAATAATATTTTCTGTAGTTTGAGACTGTAATTGTGATTGTGATGAAAAGAGGCGATCGCTTATTTTAGTTCTTGATATATTTATTATAAACTAACTTAAGTTTTTTGAATTTTCACAATTTATAATAATTTTTATATTTGTTGAATGGGAAGTTGATCAACTATTTTTTGAGCTTTTTCTAGTATCGCTATAATATACAATTGAGTTTAACTACTATTCTTTTATATAAATGATAATTTAGTTTCAAAAAAATGTGGCGATCGCTTTATTGCATCTGATTTAATTTAACTTGAAAAATTGCCTCAGTTTCTTTTCTCTCTATAGCAATCTAAATCATTTATGAAAATTACTAGTATTGTGAAAAATAGCTATAAACACTCTTACTTTTGGTTTCTCTCTTCAGGATAAGTACCTTATAGTCACCCATCTTTTTCAGAAATCAGATAGAATTACTATATAAATTTATGATAGTAGAAGATAATTAATATTTTCCGTATTCTGAATCATTAATAGTTCTAATTCGTGAAACTTTTATGAATTCGTAGGGATTTTATGAAATATATTTGTAAAAGTGATTTGTTCATCTTCTCAAATCTTAATTTCCATTGTCCTTGATTATAATTTATAAAACATCATTTATTGCTGGTAAATATAAATTATAGCAATGGAATAAAAGATTAAAAATCTGAATTATTTCGGTTTTTTTAGAGATTAATCTTGATATATTCAGCCATACTTATATGGCTATATTACTAATATTTTTCATAACAAAAGAAATTGATTTGCTGATAAATATTTAATAGTAAATTTAATAGTAAATTATAAATAATAATAGCAGTTTATTTGTATTTATAAATCAGAAAAATTAACTCTATATCAAAACTTGAAAGCAGTTTGTCTGTCTTTATAAATTAGCAAAAATAAACTATTTATCAAGGCTTTAAAATTGACTCAAATTTTGTTGTATTAAATTTTTATATTACTTTTAAATTTTTACTTTTTACTTTTTACTTCCATGAAACAGTTTCTCGCTTTCGAGTCATTCCTATAATTCCTTCAACTGTAAAATATGAAATATTTTCAATAGTAAAAAGTATGTGATTTCCGGCAAATACCAGTGGTAAACTTAGAAATATTATCTTGCTGTAAAAGTACTTTGAGTTCATAGACTGAGAAAAAATTAACTTGGCTTTCCTGACGCTTTACCCTGGGTAACGGCTTACTTACCATATAACTTGGTAGCCACGATGATTTTGAAGTTGAATAATTTTTCATTACATTGGCAATTATTGACCCAGTAAGTGGCTTAGGATAGGGGCCATTTTACCAGAATGACTTTACTATTAAACAACAGAAAGCGCTGTAAATCTTTTGTTTTTAAAGATGGGGTAATATTTTGACTTGGTTGGGAAAATAAAGGTTCAGAAAAAAGGCCCTTTTTTTGACCAATACCAATCTTTGGTTCTTCTCTTGAGGAAATTTGTTGTCCACCCATATTGGCCCTAATTTCATGCCCATACCCTATTATCTGAAACCCTTATAAAAACACAGTGGATTTTCTAATACAATGCTCCAATAACTAACCTGCTGAAAAAATTCTCAAATGGCTAAATACTCAACAATACTAGATATCCTAAACCATCGCTCCCAAAATCTTCCCGACCAAATAGCTTATACTTTCTTGCCCGATGGAGAAACTGAGTCTGGTCACTTAACCTATCAACAACTAAATGTCCAAGTACGAGCGATCGCTGCCCACCTCCAATCATTCATTACCCTACAAGACCGAATATTAGTCATTTATCCCTATACCGCTGGGCTAGAATTTATCGCCAGCTTCTTTGCTTGTATCTGTGCAGGAGCCATCGCCGTCACCAGTAACCCTCCCCTCAACAACGAAGCTATAGCCAAACTCCAAGAAAGAGTCGACTCCTGCCAACCAAAAGCCATCCTCACCACAGAATCTTTTTTACAGCAAATTAAAAAAAAATTAGCGAAAAATCTAGACTTAGCTCCCAAACTCAACCAGTTACCCTGGATCGCTACAGATAAAATATCATCCTCTGAAGCTCCAAAATGGAAAGAACCAAAAATAGAACCAGACACCCTCGCCTTTTTCCAATATACCTCCGGTTCCACAGGCAAACCAAAAGGAGTAATGGTAACTCACAGCAATATCTTACATAATTCAGAAATTATTTATCAGTCCTTTGAACATTCAGCAGAAAGTCAAGGGGTAATTTGGTTACCCATGTTCCACGACATGGGACTAATAGGCGGAGTAATACAACCTCTATATGGAGGTTTTCCAGTCACTCTCATGTCACCCGTAGCTTTAATTCAAAAACCCATACGTTGGTTAAAAGCAATTTGTAAATACAAAGCAACAACTAGTGGGGGACCCAACTTTGCTTATGACTTAGTTTCTCGTCAAGTCACCCCAGAACAACTACAAAATTTAGACTTAAGTAGTTGGAGTGTCGCATTTTCTGGAGCTGAACCTGTACGAGCTGCAACTTTAGAAAGATTTGCCCATACTTTTGCACCTTGTGGGTTTCAGCGGGAAGCTTTTTATCCTTGTTATGGAATGGCAGAAACCACTCTATTTATTAGTGGTGGAACAAAAACAAAAGCTCCAGTTATTCAATATGTAGATGCTGAAGCTTTGGCAGAAAATCGAGTTGTAGTTGGTCGTGAAAACAGCAAGCCAGTGGTTAGTTGTGGTTGGGGTTGGTTGGGTGATGAAATTGCCATAGTTGATCCAAAATCTTTAGCTAGACGTTCACAGGGGGAAGTAGGAGAAATTTGGGTATCAGGTGCTGGTGTAAGTAAGGGTTATTGGCAGCAACCAGAAGAAACAGAACAAACTTTTAATGGTTTTTTGGCAGATAAAGGACCTTTTTTACGGACAGGAGATTTAGGATTTTTACAGGATGGGGAATTATTTATTACTGGTCGAATTAAAGATGTAATGATCTTGTGGGGTAGGTATCGTTATCCTCAAGATATTGAATTAACTGTGGAAAAATGTCATCCAGCTTTGCGGTCTGGTTGTGGAGCAGCTTTTTCTATAGAGGCAGAAGATGATGAGCGGTTAATAATTATTCAGGAGGTAGAGCGTAGTTATTTACGAAATTTGAATTTTGAGGAAGTAGTGGGAGCTATTCGCCAGGCAGTTGCTGAGGAACATACGGTGGAAGTTTATACTATTAGTTTGTTGAAGACTGGTAGTATTGCCAAAACTACCAGTGGTAAGATTCAACGTCGGTTATGTCGCAGTCAATTTTTGGAGGGTACTCTAAATTCGGTTGGTAACTGGCAACTTCAAGCTGAAAAGGGTAGTGTATCTGAATTAGCCAATAATTCTAATTATATAGATAGTGAAAATTCTTAAGGGACAATTTTATTTGAACAGATGGAATTTCTGAGCAACTATTTATTTAATATAGCACTACAAAAAAGTTGGAGTTGTAATACTATTTATCGTAAATAATGCTACTCATTGAAGGTAGTTAACTAGGGCTGGAAAAACCACAGAAGTTAGTTAATAATAAAATTACATCAATAAATAGTATTTAGAAATAGAAAATCCAGGTAAAGTACAGTTTTTGATAATTTCTATAATTCCATGCCAATAAAAACATTTCAATTCACAAATAAAACAATTTTTTTATCACATTAACTACAAACAAAAATAGCTTTCAGATTACTCTATCAATAAAATCTTTGTTTAGCTCATATCATAAGAGTCAAGAAAACTTTTGAAACCCACATTTCCCAGACGTAACTCAGATTATAGATATTTTGAAAAAATTCTAGCCATAAAATTTTTCTTTACCTAATTTTCCTAGTTATTGTTAACTGTTTATGTCAAAAAATCGGGAGTATTTAAGGTTTACTGAAAAAGTCTTGGTGAGGGTTCTTCTACGGCAGTACGGAGACGCCGAAGCACAGATAAATGGACTGTTCACTAGGTCCGGTATAGTCAGAATTTCCCCCTAATTTTTGGGGCTAGATATGCCATAAATCCTATCCATACATTAAACTTAAGCCATCAAAATTATGGTACTTTTTGAAACTTTTTAGTTTAGCTAAAGTATAATTTCTGTCAATGCTTTGAGAATTAATCAGTAAAATCTATTAGTAACTTAATTGAATGAGTTTTCACAGATAAATTTTCTCGGGATATAAAGGTAGCTATTTCAGTTACAATTAACATCAGAACAGGAGCGAAAAATATTTTCATATCCTCCGAAATTTCTATTTAAAAATATTCTTGATTGCTTTTAACTTTTTTTCATTTCAAATAAACCCAATCAAATTATTAGATAATATTAACTACAACTATTTCATTTATATTTGACTATTTTTTAACGTTACTCTGTTAAATTGCAGCCAAGTTGTTGCCAATTTATGTTTACTAATTTTACAGATTGAAACATCAGAAATACCTAACTCATTGTCAGTTTATTTGTGATTTTCTTGACTTGATTTCTCCCAGGTAAGCTAATTCTTTTCTTAACTTTTCTGTGACAAAATTTTGGAGTTAACAACACTTTCGTCACAGTTGCTACTCAATCCTCGAGTATAGAACAATTATTTTGGCTAATTTCAAGAATTATTATATAAACTTTACAAAACAATATAATAATTTTTTTTAATATTAATAATTGATATTTGTCTTATTATAAGTGTATAATTATAAGGGCTACGTTATTTGTATATGCTTGATGTATAGCTCAACCAGTAAAAAAAATAGAGTCTGTCAAGCTAAAATAATATAAGTTAACATAGCATCCAATAATAGTTTGATTTACAACATTAACTATGAAAATTCAAGTAGGAGATCAAGCACCGGAATTTACCTTACCATCCCAAGAAGGAACCGAAGTTTCTCTATCTGACTTCCGCGGTAAGAAAAATGTTGTTCTTTACTTTTATCCCAAAGACGATACACCTGGGTGTAAGATACAAGCTTGTACATTTCGAGATCAATATACCATATTTAAAAATGTTGATGCTGAAATAATTGGCATTAGTGGAGACTCCAAACAATCTCACAAACAATTTTCTACTAAATATAGTTTACCCTTTACTCTTTTATGTGATACAGACAACAAAGTGAGACAATTGTATGATGTACCTCCTACCCTCTGGATCCTTCCAGGTAGAGCTACTTACGTTATAGATAAAGAAGGAATTATCCGTTATATCTGTGACTCTACGTTTGACTTTGAAGTTCACTCCAAAGAAGCGTTAAAAGCGTTAAGAAAGTTAAGAGTCACTGTATAACATAGCCCAGACGGGAAATCAAATATCAAGGCGCGTGACTGGGACTAATCGCACCTCCAAACTCCTTCTATTATGATGTCCGGACAATTTAATATCAAAAAGTTTTTGTTTGTAGTAGAACTTGAGGAGATGAAATATCTATACTGACTCCTCAAAACCTACTACAAACTTTAATTAGAACTATTAACTGGACATGATATTAAGATAATTCTAGATATGAGTAGATTTAAGGCCTGCTGCCTCACCAATACTATCGGATACTTTTCCATTATTACCATTATCATTACCATTAGGTCGTGGTTGAATTAAACCATAACCACCATGATGGTAACGTTTGTAAATAACATTAATTTCACCTGTTACTCCATTGGAAAACATATAGAAATCATGGTCAATAAGTTGTAGCTGCTCCAAGGCTTCCTCTACTGTCATACTGGGCATAGGAAAATATTTAGTCCGTACTACTTCACTGGGTAGCTCTGCTTGGCGATCGCCAATTAAATTCTCCACAACTGGCTGTGATTCAATCAAATCAACAGTTTTAGTTTTATTAACCTTAGATTGACGCTTTTCTTTGTACTTTCTGAGTTGGCGTGCAATTTTATCTGCTACCAAGTCAATGCTAGCATACAAATTTTCGCTACTTTCCTGGGCACGAATGACTGTACCGTTAGCGTAGATAGTTACTTCTGCTGTCTGCTTAGGATTTATGCGCGGATTTCGAGCGACTGACAGATGTACATCTACTTCGGTGGTTAGTTGTTGAAAATGATTAACTGCTTTTTCAATTTTTTGATTAACATATTCGTGAATGGAATCGGTTATTTCTATATTTTTACCCTGGATAACAAGCTTCATAAGCTCCCTCCGCTAATATTCTGGGCTTACTATTATTATATAAGGATAGCACTTTGTATGATCCCCAGCATCCTATCTTTAGAATCCTTTGCATCCCTTGACAATTCTTGATTTTTTTTGTCCTAGTTTTACCAAAAAATTGAGTTTAAAGCTAGACCCACCCATCAGACGACTTTTTGGTTTTTTTAGATATATACGTTATTATTGTATTAATTAATTGTAGGCAGGTAGTTACCAGACAAAAAAGGGACGCATCACGCAATATCTTTGACTAGGGTCAAGCTAGCAGCAGCCTGTTAAACGTCAAGCAACTGAGGAACTATAGCTCAGTTTTTTATCCTTGCTTTTATGTCGGAAAGGATATTAAGAATATAAGTTTTCTCAAGTTACTGAGATTAACTTATTTTTATTATTTTTTATTTTCCGTTTACCGAAAAATTGATTAAATTGAAAACCTCCTCAAGAAGTGAGGGTTCGCCAAGGTGGCAGCAGCCTTAGATACGTCAAGCTTTATCCTATCTAAGGCTCGTTATGAATACTCGTGCCTAACAGCGGGGAAGGATGTTAACAAATTATCGAAAAATTGGGTTAAAAAGCCTAGTCTATAAGCGACTTTTTAGTTTTTTTTGAATACATAAGTTGTGATTTAATTAATTAATCGCGACTGGGCAGTCCGAGACAAAAAACGGACACGTAAGGCTTAAGTAAGCTATCCTAACCCACCCCCCAAAAGGGGGTAAGTTCATTAGTCTGTGAAGTGCACAGCGGGTATGTCGTGAAAAACCTCAACCTGCCCTTGAACAACCCAAGGGAGAGCTACCCGCGCACCTAACAGCCGGGGAGCATTTTAATCTTCTTTAGGGACGTTCCATAAGAGCGCCTCTACCTATTCTCTACTCTAAAATGACTTCTCAAACTTGCCAGTTAATTTGTCCAGGATTAACAAAGTATTCGGTGGCCTGGGAATGGCAGCGATCGCTTGTTCAACAACGTCATAATTGTCCAGAATTGGCTGATGTTCTAATATTATTGGAACATCCACAGGTTTATACTTTAGGACAAGGGGCAAAATTAGATTTTCTTAAATTCGATCCTACTCAAAATAAATACGAACTCCACCGAGTAGAACGAGGAGGAGAAGTAACATACCATTGCCCTGGCCAACTGGTAGGTTATCCAATCCTCAACTTAAAACATTATCAGCAAGACTTACATTGGTATCTACGACAATTAGAAGAAGTATTGATCAAAGTCTTAGATATCTTTGGTCTCAAGGGTGAACGATATCCAGGTTTAACAGGGGTTTGGTTGGAGGGTCGAAAAGTAGGAGCAATTGGGATTAAAGTTAGCCGTTGGATAACCATGCACGGCTTTGCTCTCAATGTCTCTCCTAATTTAGAAGGTTTTCAAAGGATTGTACCTTGTGGTATTTCTGATAAATCTGTAGGTAGTTTGGCTCAGTTTATTCCTAGTATTACTACAGATGAAGTACTTCCTCTAGTAGCTAATGCTTTTGCTAAAGTATTTGGAGTCAAATTAGTCAAAAGTACAAATGCTATATTATTTTGACTAGTTATCAGCTTTTAGCAGCTCTGGGCTCAAGCCCCCTTGTCCCTGGCTTAAAAAATTATCCTACTGATTATTTGACTAAGTGTTGACTACTTCCTTAAAAAGGAATAGGATCAAAATCGTCAGCTGGTAATTCACTCTCTACTAGATCAGTTTTTGATTCTTCATTAACAGTAGAGCTAAGACGAGATTTTAAATCTACAACATTACTATATTGTTCTTCCTGTGATTGCTGTTTAGTGAAATTTCTCTTACTGGATTTATTTGTTGGCATTTGATTTTCATCTTGAGTCATAGCCTCAGAGCTAATAGGATAGATTTTGGAGGCTGTTAATTCAGCTCGTTTTTCTTTAAATCCTTCTGGTCGTTCAATAGTGTTTATACTTAAGCGGCCTTCAACAATAACATAATCTTCTTGGTGATATTTTTCGTTGACTTGTTCAGCTAAGTCTCCCCACGCTACTACTTTTAGTAAAGCAGGTTTATTATTAACTCCTAAATTAGGAAATTCTACTATCATTTCTGCTACTGGCAATTGAGAATCTGCTGTATAGCGCAGTTCTGGATCTTTGGTGATTTGTACCATTAATATACAACTATTCATTTTAATTTTTGACTAAGAATAACTTGCTTTGAACAAAGGAATATGGATGATATTCTTTGATTTTACCAATATTCATCTCAACTTATTTATACAATTATGATATCTGAAATAAAATAATTTGTAATTAATTCTCAAATTAATAAAAATAATCAAATTTATACTAGTTTTTCGATTCTCTTTTCCCTAATCGTAACGATATTTTTATAGATTACTCAAATCTAGTTATAGGTAACTATACAAAATTATTTGCCCAAGAGATGTTTACACAGTTAGAATTTTAGCTTTGCAAGTGTATAATTTATTTTGTTTAAGCACTTAACTCTCCTCAATAATTGGTGATAAATTGATTACTTGCTTATTTTTGTATTTCCTAAAAACTGGACTTATCGCTTTCACAGTATCGGGATCCTTTTCTGTATCAAAACATCCGGTTTTTGATGGTATGTATTGCTTTTCTTGGGAAAGCTTAATACCCTTTAAATCATTAGCTATTTTTGTGTCGTAGCAATGCCGATTAATAGTTGCTTGTTTCTCAAGCTATCGTCCCATCCCTAAGTTTTTAGTATGACTCTCATGAATGTCTGTATTTTTTGCCACTAAGGAGGTATTTATGAGGGTTGATGTTCCCATTTTCTGCTCCACTAAACCTATGAACATAAACTCTCCATAACAATCTTATGTTGGTATTATCCAAATATATTCTAACTTTTTGGAAATAGGCAATAGGTCATTAGCAATAGTTTTAAATTTTATTAGTTTTGTAATTTTTACAACGGTTTTATCGGATTAATATAGATTAAAGCCAGTTTTTTCAATACCTTTAATTATCCTTAAATCTATCAATACTAATTTATACCCTCAAGGGAAATAATTAGGAATAGCTGAATAAATTAGAACCATAATAATATATTATTTTTAGCGGGACTTTAGTGAAAAAATAGTAAAAAAAAGGGTATAATGTATACCTGATATGTATTTTACGTTAATTACTGGCCTGGGAAAAGTTTGATGAAAGAAACAACTTCAGTGGCCATGCCCTCTTGTTTCCATCGATGGTGCGATCGCTTTAACAATGTCTTTAAAACAAAAGCCCAAAAAACAGGGTTTAGGGAATATATAGGAGGATTACTCTTGAGAAAGCGATCGAAAAAACTTGTCTCAAATTGCCAACAACACTGTAGGTCACACGTACCACAAATTACGGCATTTTCTAGTTCGAGCAAATTGGTCTGTAGATGCTGTGAATGAGCGTCGTCTTCAAGTAATGTGGGAACGTCGCCAAACAAAACCTTCTCGATCCTATTGCTTTAATTATAGACGATTCAGGCCACAGAAAAAGTGGTAATTTTACTGCAGGAGTAGGGCGGCAATATATAGGAGAAATAGGAAAAACAGATAATGGTGTAGTCGTGGTGACAACTCATCTTTATGATGGAGTTAAAAGTCTACCTTTAGACATAGCTTTGTATCAGAAAGCTGATTCTTTTCCAAAAGGAAAAAAAGACCCAGAATTTGTCAAGAAACCAGACGAGTGCAATGTCTCTAGTAGATCAATGTTTGTCCAGAGGACACCAACCAGAAATTGTGTTAATTGAAATTTGGCTATGGTAACAATACATCATTCTTAAATCAACTAGAGAAAAGAAGTTTAACTTATATAGGAGGATTAGCTAAAAATCGAAAAGTCATCATTAAAAAACAAGATGACATTAAAGAGGAAATTAGATTAGACAAGCTGGCAGAAAGTATACCTCAGAAAGCTTTCAACTTAGTTCAACTAAGTACAAAAAATGCTAGAGAAGTTTGGGTAGCTACATTAGAAGTAGAAATATCTAGGATGTCAGGTCAAAAAACTATAGCTATCGTTATGAATGCTAAAAGTTTTTCTGAGGCCACTGATATTAACTATTATATCACTAATAGAGAAGACAAATATGTAACTCCTGAGTGGATATATTCTACTTATTCTCAAAGAAATTGGGTGGAAGTTTTCTACAGGGAAGCCAAAGGATGGTTAGGATTAAGAGAATATCAAGTCAGAGATAAAATCAGCCTTAAAAGGCATTTTATTTTAGTATTTTGTGCTTATACATTTATTATCTGGCATCAGTTAACAGGAGGTATAAGAAGGCGTTGGGCTAACAAACCATTAAATACGTTTACTGATACTTTAGAAGCATTTCGTACCGCAATATCTTATCGTTTTGTTGAGTGGTTAGATGAAAACATCGACGTATTTACCGCTCATAAAGAGAGTTTAGGGTTTGTTTGGGCTTGAAATTTGCTAAAGTCCCGTTAGTTGTGGCTTACCTTGATAAAAGTGTAAAAAAATTACGAAGTTAATATTCAAAACTTGAAAGTTACGAAATTAATATTTACTAACAAGTGATTTTTTCCTGACCTGAGTGAGAAAAATCAAGGTAATGTAACTATTAACAATTCCTTATTCCCTACTCCCTAGCCTTACTAAACAGATTAAAAAAAATCTAATTAATAGCTGATAGCTGATTAATGAATACTTATAAGTTATCTAACTGATTTCTGGTCATAAATAGGTTGACAAAATCATGTATCATGTTGCGATAATCTCTTAAGGTTTTATCTACCCAATCTCGATCGTTACTATCTGCATAAATATGTACTAATGGTTTTCCAGCATCAGGTAAAACTAATACCCAATAGTTATCTTGATGATTAATAATCTTTACTCCATCAGTTAATTCTAACTTTTCTGGTGGGTTAGTTTCTACTAAATACCGCATTAATGCTCCCTTTACTTTCCAAGGACAACGTATGGTATAACAGCGATGAGTAATAGGAGGAATATCTGCAGTTATTTGTCCTAGCGATCGCTCTTGAATAGTTAACATTTCTATGACTTTAGCGATGCAAAACATAGCATCAAAACCAGGATGTAACTTTGGGAAAATAAATCCCATATCACCACTTCCTCCTAGCACCACATTATGATTAATTTGGCAAGCTTTCATTAATGCTGTAGGATTAGCTTTTGTCCGAATCACATGACTATCATGACGATGAGCAATTTGTTCTACTGCAGCAGAAGCATTAATTGGTACTACCACTGTACCCCGTGGATGAGCTGTTAACATTAGATTTACCATTAGTGCAGTTAACGTTTCACCACGAATGGCAGAACCAACTTCATCCACTAATATTAATTGTTCTCCATTTGCTGTTACCTGAACTCCAACATTAGCTTGCAAAGCTTCTACAACCCGACCTAATTGATCTAGTAAATTTTCTCTTTCTTCTATCCCTAAAGAAGTTTCTTTTAAACTAGCATTTAGAACTACTGCATCACAACCAAATTTAGTTAATAATTGTGGTAATACTGCTCCCGAAACACCATAACAATAGTCAATTACCACCTTAGATTTACTATACCGAATTGCCTCAGAATTGAGAAGATTTTCAAAGCCTTTACTATAAGCATTTAATACTTCATGACGATCAATCATATTGCCAATTTCTGATATTTGTACTCGGCGGAAATCTTCTTTAAAATATGCTCCTTCAATGTTTTTTTCTTTCACTTTTGAAATATTAATCCCTTGATAATCAAAGATTTCAATTAATATTTGATCTGAGCGATCAGGAGAAAGACGTACATGAAGGCCACCCACTAAATTCATGGTGGGTAAAATTGTTCTGGCAATAGGAATAGCGGTAGATTGTAAATTGATTACATTAATTCCCACCGACATTAAACCAGCAATTAAAGACCGAGAAACCATCCGAGATATATTACGTTGGTCGCGAGAAACTGATACTGTAGAACCATTTTTTAAGGTAGAACCATAAGCAGCTCCTAACTTAACCGCAAAGTCTGGAGTAATATCAATATTTGCTAATCCCTGCACCCCACGTTGTCCAAATAAGTTTCTCTGGGCAGTTGTACCCCAAATTAAGTTAATATTCAGAATGGCTCCTGATTCAACTGTTTTACTAGGCCATACTCTGACATGAGGACTAATTTGGGCTTCTTCTCCCACAGTAGATAAAGAACCAACTACAGCACCTTCCAAGATTTGGGCACGACGATGTATCCTAGAACCTCTACAAATTACACAACCTCGTAAATTGGTATCCTCTCCCACCAGTGTACCATTCCAAACAATAGGACGCTTGACATTAGCATCTGCGCCAATTGTTACATTATCTCCTATGACACTACCTAGTTCAATATGAACTCTCGGACCAATTCTACAGTTATCTCCAATTAAAGTCGGAGTCTCAATTTTAGCTGTTGGGTCAATATAAGTATTTTCTCCTATCCAGAGATTTGGCGATCGCTCTTTATAAGGCAACTCAAGTTTTACTGTGTGTTGAAGTGCATCATATTGAGCTTTCCGATAAGAATCTAAATGTCCAACATCACACCAATAACCCTCAGCAATATAGCCATATATCGGCTCATTTTTATCTAACAATAAAGGAAATAATTCTTTAGAGAAATCACATTCTTGATTACTTGGTAAATAATCTAAAATTTCTGGTTCTAAAATATAAGTTCCTGTATTAACAGTATCCGAAAATACTTCACTTGTAGAAGGTTTTTCTAGAAATCTTTTAATCCTCTGCTCTTCATCTGTAATTACTACTCCAAATTCAATTGGATTATTAACTCGCGTCAATACTAACGTAGCTTTTGACTTATGTTTTTGATGAAATTCTATAGCTGCACTTAAATCAAAGTCTGTAATTGTATCTCCACTAATTACTAAAAATGTTCCATCTAAAAGTTCTGCAATATTTTTTACACAACCAGCAGTTCCTAGAGGTTGTTCTTCTTCCACAGAATATGTCATCTGAACTCCAAATTTACTGCCATCTTGAAAATATTCACGCATTACATCAGGCAGATAATGTAAAGTAGCAATAATCTCCCTAATTTGATGTTTTTTTAATAGATTAATAATATGTTCAGCTATTGGACGATTTAAAATTGGAACCATTGGTTTAGGAAGATCGCAAGTCAGTGGTCTGAGTCGTGTTCCTGAACCTCCAGCCATCAAAACTCCGCGCATAATTTCTCCTTTGTTAATTTTTTTTCTATATTTATAGCAGTCATATTTAGCTTATGAATAAAACACAATTGTATAAGTAATAACGTTTTACGATCCCCTAAGTTAGGAATTCATACATTAATATTTTATAGGCTCAAAACTTTGACGCGCTTCTATATTTCAGGAAATTCTTTCAAATTTCAGGTATATTTAGGTAGTGTATCCTAAGTTAATCAAATTCCTATAATATTCTGTCTTTTTGAATACCTACTGTGGAAAAAATTTAGGCAATAGGGAAAATCAGTTATCAGTTATTAGTACATTCAGCAATAGGAATTTTTCTCATCATAAATTGATTCTTATACTATTAAAATTGGATGATTGAGATATTATTTATTGTTCTTTAAATCCATTATGCACTTTGATATTTAATTTCTTAACCTTAGTTCAATTACTATGCTTTCCCCTAGAAATGCGATAACTGTAAACTTTTAAATATTAGAGCATTTATAATTCATTTATTTTACTTAATTGCCAATCTTTTATATTGTTTTATTTAAACCTTACATCAATATCCAAATCTTAGATTATATTTAACTTTCACAACCTAACAAAAATTCGCAACAACCAAGGCAAAGTCAGAATTTTACAAAACTAAAAATAAATATTTTTTATGATTTTTTTTCAAGTATTATTGGTTATAAATTTAAGCTTGTTTTTTGCTTGAATATATTCAAAAGCTGAATGGTAACTTATTTCCCATAAAAAGCCGAAATTTATCTTTATTCCTTAGAAAAAACTATAACAAAGTGAATATCATTTAATTAATTAGAAGTGCATTACTTATTAAGCAATCCTATATAAATTGTAATATTTTGCTAGCAATTAGGAATCAAGAGTCAAAAGTTAGAATTTAAAAGATTTGCACTAGAAATTAATTATTATAAAAATAATCACAACTAATGATCGGATTACTATAATAAGGTTATAATAATTATAAAAATATTCAACTTGTAGCCCAGTTTAAGATTGATTCAATAATCTATAATAAGGCTATGTCCAAAAAAAAAGAACCTTTTCCGAGTTTTTGTGCCATGGGTACCATTATTAGTTTATTATTGCTTGTTATATATGGAGGTGGAGCCTGGAAGTTCTGGAATGGATTTAAACAAACCAACTTTTCTCAGAGCTTTCAGAGTCGTTTGGTCTTATCTATATTATGGCCTGTTTTGTTAATTGGTAATAAATCTTATCGTAAGAACTTTACAAAGGCTCTTAAGGGTAATAGACGATAAAAAGAAATATGTCTCAAAAAAAGTCTGCCTTGTCTGCAAATAACGAGCAATCTTTCTGGTTTGCTAAAGAAAATTTAGATAATTGGTATGCTCAAATCATGGCAGTACAAGCTCGTTTTGAGCAAGAGTACCGCGGAGAACCTTTAGAGTTACCCCCCGAAGTAAAGGCAATGCCAATATTTCACGATTTTGCCTCTGGTAATCTCACAGCAAAAATAGTTTCTCCTTTTTGGGAAATAGCTAAACCTAAAAAAAATAAAAAATGTTTGGATATTGGCTGTGGAGTGAGTTTTCTGATTTATCCTTGGCGAGATTGGCAGGCTTTTTTTTATGGTCAAGAAATTAGCACTATTGCTAGGGATAATCTGAATAAACGAGGTTCTTTACTAAATTATAAACTATTTAAGAAAGTAGAACTGGGACCTGCTCATCAATTAATGTATCAAGCAAATGAGTTTGACTTGGCGATCGCTACAGGGTTCAGTTGTTATTATCCTGTGGATTATTGGGAACTTGTATTAGAGGAAGTAAAACGGGTTCTAAAATCGGAATGTCACTTGGTTTTTGATGTTATTAATTCAGAACAACCACTGGCAGAAAATTGGGCAATTTTAGAAACTTATTTAGGGGCAGAAGTATTTTTGGAGCCACTAGAAAAATGGGAAAAAATTATTAAGGCTAAGGGTGGAAAAATAGTAAAGCAACAATCAGGAGAATTATTTCACATGTATAAAGTAAGGTTTTGAATGGTAGAGCACGAAATACGAAATTGTCTTGAGTTAGTAGCTAAGGATCGGTTGTTTAAGTGTATCTAACGGCCGGAGAATATTTTAAAAGTATTCATTATCTTTTCTTGTTTCTTTCTTTAAAATTTATGTAGAGAGTTTTATATTTTTGTTCATTTATTTATGATTTATTAATCAGCTAGTACTGTCGAGAATTAAGCAAAATTTAGCCTAACTAGAAGTAAGAATTAAGCTCATATAAGTATCCTACTAAGTAGTCGTGGAAATTATTAAACATCTATACCAGCTAAATTATTTGTCTTCTTGTGAGCTGAAATAATTAGGGTTGGCTGAAAAAACTTAAAGCATTTACAGAATAATACTGTAGTTTTTTTTATTCAAAAAAAGAATGTGCAATAGTTTTGACTTAACAAGACTCAAAATGAAGTACTTTGAGCTACTAATGGCAGAAAAACTAAAAGAAAATACTTCCGACAAATCTTCTGTAATTCCCATTTATCCCTGCCTCTTTGCATCCTACCCTCACCTATAAAACTTATTGAGCCAAATCCTAATGAGAATAAGTAGATAATAATATAACGGTGCTTATATTGTGTTGTTCAAAAAAAAAATACAAATTTACTCATGGTACGAATAATTTTGAAAAAAATTAGTATTATTGATTTATAAAATATAGGACTTCTTGTCGCTGTTGTTCATTATTAGGGTAATTAAAATAATCACCTTAATTAGTTTTAGCTTGCTCCTTTCTTGTTAACAAACGCCTAATTGAAGCTTTTTCAATAGACCCAACTAAGATCCCATTTTCATCAATAACAGTTAGTTCACTGATTTGCTTTTGCTCTAACAAAGAAATTACTTCTAATAAAGAAGTTTTAGCGGTTACAGTCTCTATCTTTGCTAAAGGTTTTGTTAATGTTTTTACCTGAACCAAAGGCCATTGGGATGTATTAACTATTTTTAAATCATCAACGTTAATTACTCCTACAAACTGCCCCATTTCATTTATCACTAAAAACTTCTTTCTAGCTTCTTTCCCAATAACATATTCATTCACAAATTCTCGTAAAGAGAGATTGTTTGATACAATTGGATTATCAGGAATAATAGCATCTACTGCATTTAAATCAGCAAGCATACCTTGAATTTCTCCATATTGGGCAGAGCGACCAGCATTTTGTAGTAGAAACCAACCAATGAGAATATTCCAAAAATTAGGAATTCTACTAAATAAAAATGCGGGAATTAAACCAGAAATTATTGCTAAACAACCAAATACTTGACCTACTCTACTTGCAAAAATAATTCCTTTATAAGGGTTATTAGTGATTTTCCAAACAATAGATTTAAGGATATTACCACCATCAAGTGGTAAACCTGGAATTAGGTTAAATAATGCTAGGAATAAGTTGATATAAGCTAAAAGTTGAACAATGGATTCTGCTGGTCCAGTAATGGATGTAAATATATTAATTGATACAAAGAAACCGCATAATAATATACTCACTAAAGGGCCAGCAATTGCTACCAAAAATGCTTCTATAGGAGTCTTAGATTCTCTATCTAAACTAGCTAAACCTCCGAAGAGAAATAGGGTAATTGATTTTACTTTTATTCCCTGATATAGAGCAACAAAACTATGCCCTAACTCATGGGCTAAGACAGAGGAAAATAATAATAATGCTGTTATTAATCCTAGTATCCAAGGTAAGGTATTACCCAATTCTTGAGAAAATTGAGTTGCTAGGTCGTTACCATAAGTTAAAGTAAGGAGACCTAAGACTATAAACCAGGATGAGTTAATGTAAAATGGTATGCCAAATAGGTTGCCGACACGAAAAGATCCATTCATAAATTTATCCTATAAAGTTAGTCTATTAGTTAAAACTAATTTTTACTTTTTTGAAATTTACATATTTAATGTAACAAAATATCAATAAGTTGTGTTGTTTCTTGAGCTAGTGATATCCCTCCCTTAATGTTCGCTTATAGCAAAATTAACTCGATTATTTTCTCAGTAATATGACTAGATATTTTATCACAATATATATCTGGATTCAATTAATTCAGGTATAGAATTTTATATTTACCTCATTAAATAAAAATGATATGTGAATTATTAATTAATTAGATTATAACAAATATGATAGTAATAACAACATCTTTACGAACAAGGGGAAGAATGAATATTTTAGATTAACTAGATGATTTTATTAAAAATACAAGATGGTCTAAAGAAACAAAAATATTTTTGGTAGTAAAACGGATTTTTTCATGTTCATATTATTATCAAATCAAATAATTATTATAAAATTTGCTCGCAGTTTTATCAGTGGATGGAAGATAAGATAGTTTTTGTTGAGGGTTGAGAAAGTTTAAGGGTTTAATCTAAAAGAATGAAAGATTTATAGCCACAAAAAATATTAGAAAAAATTTACCTATGAAAATAGTAATTTTTGAAAGTTTTGACTCTCAAGCTCAGTATTATAGTTACAGAAAATCTCAGTAAACATTTACTTTTTTCTCAGCTAAAATTTGATAACTTTTACTCTGAAGCTCAAGGTTAGGTTCATGGCTTAATCTCCAACAATTTCAGAAATTTTCCTACCCTTAAAAAAAGGAAAGCAGCCTGAGGTAAAATGCCAAAATTTCCCCTGTAAAAACTTACTATTTTTACAGTTAAAATTTGACAACTTTTACTCTGAAGCTCAAGGTTGGGTTTATGAATTAAGCTGGAAAATTTCAGAAATGTTCTTAATTCTTAAAACCAGGGAAGTAGGCTGAGATAAAATACTATAATTTTCCCAGAAAAAACTTACTATTTTTATAGTTAAAGTTTGACAAATTTTACTCTGAGGCTCAAGGTTATAACTATAGAATATCTAAGGAAAAACTGACTATTTTCCAAGCTAAAATATTATAGTTATTATTCTCAAGATTAACATTAGGTTCACTAACATCTTGCTCCAACAGATTCACAACTTTTTTTATTCTTAAACCAGCGTCACTTTCCAAATTTAATTTTACTTCTTTTCCCAAACATTCATAACATCTAAAAACCCAACTTTGATTATCCTCTGACCGTTTTAACATCATCAAAATTAAGTTCTCGGCTTCCCAACCTAAAAAACGATAAACTTGTGGCAATTTTCCATGAGATTTTTCTTCCCTAATCAAAGGCATTATTTGTACCATCAAAGGCATATTTAACTCATAACCACGTTGTACAGTTCCTGCATTTTCCCAACTTCCAATATGAGGATAAATAGCATAAGTAAATTCGTGAATTCCTACATCAGCTTTCGAGTCAGGCCAAGTCGAACCTCTCAATAAAGTTAAACGTAATTCATCTGGTTTTGCATCATATCCATATTTACAGTCATTCAATAAACTGACTCCATAGTTATCTTTACTAATATCTGCCCAATTTAAAGCTGGAACTTCCCATTTTGCTTTCTCTCTTTCTGTCTGAGGTTTAGTTGTTCTCTTAATTGCTCCACAAGGAATTTCATAAGTAGTAAAATCTGCTTCTATATTTATAGGAAAAGCTGCTTTGACTAAAGTATGTTTTTCCTGCCAGTTTACCCAATTTTTAATTTTTAGTAGTTGGGAACCTATTTCCAAAATGTAATCCTGACAAAACTGAGAATTACCTATTTTTCTAATTATCCGCAGAGAACTTTTTAATTTTCCCTGTTCTATCCAAAAAATATCTATTAGTTTTGCTGAAGATAAAGGATGTTGTTGATAATTTGGATCAATATTCCAAGCATCCCAATATTGACCTTCATCACGAAAAACTTTTAGTTTATTTCCTTCTGGTTTTCTCAGAACTTCCCGTTGATTAATCTTGTCAAAAATACTCTCTAGATTTCCTGTTGTTGCTTCTACCTTTACCCGTAATAAATTGTTCTCTAGAACCCATTTTTCTATTTCTAAACTAACAGTATTGACATTTTCAATTTTTTTTGCTATTGTTCCTGTATGGTGGGCTATATATTTGCCTATGTATGATTTTTTGTTCAAATCTGAAAATCTAGAACATAACCAAAACAAACGATAACCAACTCCAGGTATGTCAGAAGCAAGAAACAATAAGCTATTATCCGATATCTGAGAAGTAAGTATTTGCCCAGCATCGTCATAAACTTGCCAGTCATCTTCTCTGCCCTGCAAAAAGGTTAAATGTTGAGAGTTAGGTGTAAGTTCAAAAACCTCTCCCTTCTCCCTGTTCCCTGCTCCTTCAATATTCTTCTTTCCTGGAACTGAAACTAATTCTGAGCGTTGCCAATTCAAAGAATTAAAGACAATTATCGGATAAATCATCCCATCCGCAAAAGTATCTAAAGGAAAAGGTGGGGAAACATTAACATCAGCAGCAACTTTTCCCATAGCCTCCGCCAAAATTTCCTTACCCAGCCTTTCCGCCTCCGACCAATTCTGATTAACATTTACATAAGCTTCAGGAATAGCCGAACCAGGCAAAATATCGTGAAACTGATTAAACAAAACTAATTTCCAAGCCATCTCCAAATCATTCTTTCGATAAAAAGCACCAGTCATAATTGAGGCAAAAACAGCAAACAATTCTGCCTGGTACAACAAATTTTCACAACGGCGGTTCCGTCTCTTTTGATCTGCATGAGTTGTATAACATCCCCGATGAAATTCTAGATAAAGTTCATCCTGCCAAACAGGAAAAATACCTGAATTTTTCTCTACTAACTCAGCAAAAAAATTCTCAGCAGTTGAAAACTCCAACACAGGAAAAAAACCAGACTTTTGCCATCTTCTACTTATTTCCAACATATCGCGAGTCGGACCTCCACCATGGTCTCCTACACCAGGTAACCAAAAAACATTTTTTTCTCCAGTTTTTAGTTGCCATTCATAAGCATACTTTGCCATTTTTACAGGTTCAATATTTTCTCCTATAGGCGGTAACATAAAACTAAAAATTCGACTTTTATCAGGAGCTTCCCACCAAAAAATTTCAAAAGGAAACTCTGTTAAATCATTCCAACGTAACTTTTGAGTAGCAAAATATTTAATATTTCCGCCTTGAAGAATTTGAGGGAGTTGCCAACAGAAACCAAAAGTATCTGGTAACCAAGCTACAGAAGAAAATTTGCCGAATTTTTCCCAAACATAACGTTGACCGTATAAAACTTGTCTAATTATTGATTCTCCTCCGACTGTATTTAATTCTGGTTCTACCCACAAACCTGCTGTGACTTCCCACTTGCCTAACTCAATTTGTCGTTTAATTTTATTAAATAAATCTGGTCGGTTTTGTTCTATCCATTCATATAATGCTGGAGTCGAATGACAGAAAATAAGTTCAGGAAAATCTTGTTGTAGATTTAGTACAGATGTAAAAGTTCGTTGTGCGGCTTCCCAAGTTTCTTCCACATCCCATAACCAAGCTAAATCTAGATGAGCATGACCTAATAGTTTTAGCTTTAAACTATTAATATAGCTCTCAGAAATTTTGGTTATTTCTGAGTGTAAATTTAGTAGCGATCGCTCGAACTTTTCTTTCTTTCCAACTGCTTGTAAGTCTATCAAACTGATAGATTTTTTTATTCTCTCTAATTTCAAGTCAATTTTAGATTCAAATTTAGTCAAATATTCCAGTAATATTTCTAGTCTATCTGCCATAAAACCAGGATCAAGCTGATAATTATTCAGATTTTCATAGACAAACCAAGACTTTACTAAAGCACCTCGGTCATGTGCCGGACTTACCAATTTAATAGCAATAATAAAAGTCTTTCCAACTACGACCTTTTGACTCAGCAAAATTCTGCTGGAATAGTCAAATAAATCTCCTGTTTGTACTAACTTACCATTCACATAAATTTCTACATATTCAGCCCACCAAACCAAACCTAATCGTAAAGATAAATCAGTTAATAAATAACCGTTTAAATTTGGAGGAATTATCAACTTTTGCCCTAACCATAAAATCTGTTTGCCTTTTTCCCAAGCAATTTGTTTTTTTTCATTTGTTGTAGCTAACTGCCAAGTATCTAAATTTTTAACTGCGGTAATAGGTATATCCTCTTGGCAAGAGCGCCATTTGTTTTGAATATCTAGTTGGGTTAATTTTCTGAGTTGCTCAATTGTTGTGGAAATTTCGGTAATTGAAAATTTCATAAAATTTTGATTTACTGATTTAGTGAGAATGGGTATCCATAGTTTATTTTATTTCAGATATAAAACTGGATTTAGATGATCATTTTTTCTTCTGCTTAATTTTTAGAAAAAAGTCTTGAATCATCGGCTTTTAACTGAGGAAAGTTTGGCTCAAAAAGTAAGATAAATGGTCGTCTTATGTTCTGTTTATGTTCTGTTACTAAAAGTTTAGTTCAAAAACTGGTAAAACAACACAAAAAAGATGGAAACTTATAAATATTAAAATGTGGGAAAGCAAGGTTTAGTTGTCTGATAAATGTAGATGTATATTGAAAACAACTTTTGCTAAGATATTCAGATACTACTATTTCGTAATTATGTGAATTATTTGAGATAAAAATAGGAAACTGGGTAAGTTGTACTGCCGTGTTTCGACCTTGAAAAAAATTGGGGTTAAGCTGTCAAAAAAAAATGCAGGGTAGCAGCTAGGCCGGGAGATAAAGATTGCAAAAATTAAGAGAAAAATACGGTAGTTATAAGGATGTACGAATTTTGGTTAATACATTTCTTGAGTTCTCATAAAGTAAACGAGCACAATAATTTAATTGCTTGTTTACCACTACTAAAAATAAAGTAGATGAGCAAAATTGTTGCTTGTTTACCACTATTAAAAATACAAAGGAATTGGTGAAAAAGATAGACTCATAAAATTTAGTATTTATAAATGAAACAGTTGTAATACTTGGACAAAAATCATTCAGTTTAATTATTAATGTCTACTATTTTTTTGAGATTAACAGTTAACATGAGCTAGTAAAATTAGGGAAATAAAACTTTGATGCCTAGACTTTTTAAAAAAATATCTATAATTTGATTTAGATGTGCAGAATCTCTGGCTAAAAAATAGATATTTTTAGTCAATTATTATTTACATAAATTACAGGATATTTGGTGGATAATGTTCTACTAAGTTATCAATATTACTAAGGTAAAAAATAATTATTTAATTGGGATTAGTTCTAATTTTTGCCATATAAATATAAAAAAAATACGGTTTATAGAAAACTAAAATTGATAAGGTATAGAAGTATGATTATGAGGTTTTCAGATTACATAGATACAAAAAAAATAGCTAAATTTTATTCAATTATCAAATATTTTTACCTTTAATTTAAAGAATAGAATTGTATCTAATTTTTCCAAGCTATAGCAGTTTAAATATAGAAAATATGACTAAAATTATGAGATTAAAGAGTTTAAGGTATACACAAAATTATGTAAAAACGCGATTTTTACATAGTAAGGATTTTATCTTTGCTCAATGTGTAAGTTCATTTTTTCCCACTTATCAAGGTTAAGTTTATAAGTATTAATTGAAATGGCTATAACTCCAAACTCTCTAAATATTAAAGTGCACTGATATTTTTTTTATAAACAGTTTCATGGCTCTTAAAATCTACTTGAGTTAGTTTTCTGAGTTGCTCAGTTTTTTTAGAAAATTACAGAATGGGGAATTAGATTATTTTCTCAGTTTCCTGGTATGATTAAATTAAGTATCTATAACAAATCCATTAGAAATTTAAAACTAGACTTAAGTTGTGTGATTTTTTTTCTCTGGCAAGAGCTGTTTTATTATCTATGTCAATTTCTATTTAACTTGTTCTATTTTCCCAGTAAGTAATTTAAGATTTTCCCTGGCTATGTTCCCTTGTTCCTGTTTTCTTCTTTCTCTTGAAATTTTCCCTGGCTATGGTTATGGCGAGCTGAAGCCAAGGGTGGAATAAATTTTACATTATGCTATAGCTACTCCTATTCTCTTGGGGGAAATGAGCTTGCAAGAAGAATGGGTTACATTGGCCTCATGAGTCTGTTTTTTGCGTTGGACTGACCACCCGGGATTAATTAATATATATTATAACATATGTATTCACAAAAAACAACTAAAAAGTTGTTCTCTTATGGACTAGGCTTTATTTTTCGGTGGTATATTTTTTGTTTTTAAAGTTAACTCTGGAAAATTAATTAGTTTATCTAAATATCTAACTAAAAATGACTTCAAGCCCTTATAAAAGTAAAGTATTAAATTTTGTTGTAGCCAAATATAACCAAATATTAACTCGAAGCGATCGTACTTTATGTCATCTAAAATTTATAGCTACAATCACAGTTCAACTGCTACTTTATCCTATATATGTGTTGCTACAAACCTCTCGCGTCGCACTCAAAAAATTACAACAAACAACCAAAAGCTATTTACCAGAAATTAAAGAAAAAGTCAATAAAAATTACCAAACTAATGACAAATCTATTGAAGAAGTGTCAGTATTTTCAAGGCCAGTTGATTCTAGGTTATTATATCCTTTAAACCCCAACAAAACTCTGGTCAAAAAACAGGGTAAAGTTAGTTCAAGATTAGAAATTCTAAATAATTATAAAGTATCAGATATTTTAACTAGGGCCAAACAAGAAAATCCTCTAATATTAGATATGGGGAAGATAGAAGAAAAACCTTTATTGCAACTTCAAATTCAACCCTGTGCGGAACTTGTGCCAACCTTTGGAGTTCTAGGGGGAGTATGGCAACTTATGGCTTGGGTGCAAACGAGTGAAATTGCTTTGTGGTTCAATTTCTTTGATGAATCTAATATTGTTTTACAGCAAAATGAACTAAAGGACAACAATAGAAGCTTAAATAGTTACCATAATCAGGTATTATTGTCAAATTCAAATATAACTTTTGGTGAGTTTATTAATAATCTAGCAAAACACTATTTGTATCCAATTACTAAAGGTTTAGGGTTAAATGGTTTGCTGCTACCTTTGAGAAGAGAAGGAGAATGTGAAGTCGAATCATTATTAGAAACAGAAATAGATCCAGAAAATCAAAAAAATCTTTTAGCAACTCAAGATGGTACTCCAATAGTTGCTTCATTAATATCGCCATTTGAACAAGGAATATTTCAAATAGCTACCTCTTCAACAACTAAACCTTTAATGAACCCAGAGGATGTAGAAAAACCAGGAAAAAAGAAAAGTTTTCCTTTACATAAACACCTCTGTTATGAGATAATTTCGAGTTCTAATGATTATCTTAAACAAGAGGCGATCGCATCCAAAGAAGCTTTGAGAGAGATAGATGGACATCGAGTAGAAAATGAGGATAATTATAGCATAAATAGTAACAAAATATCTGTCAAAACTTATAACTCAGAAAGTAAGCCCAAGGAAAAACTAAACTGTTTAGAAGTAGAATCAGTTTCAGTAGGGTATATCAAACATCCCCTAGAAGTAATATTAGGGTGGGTAGATGTGATTATGACTTGGGTAGAAAAAATATTTGTACAGGCGTGGCAATTGTGTCAACAAAAGTTGAAAAATTTTTGATAAATTATTATGGTATAATTAGATAATATTTCGATATAATAATAAAATTGTAAATATTTGATCGAAAAAATTCGGTCTAAAACCCCGTCCTTTTAGGAGAAATAATAAATGCTGACTTTGAAAATAGTTGTAAATATCGTTGTCCTATTTTTTGTCTTGTTATTTATTTTTGGATTTTTATCCAATGACCCTGCACGGAACCCTAGTGGTCGGGACATGGAGTAAACATAATTGACTTAAGTTGATAACTTACGTCATGAAGGGTTATTTTGCGATAGTTGTTCAAAGTAATGAAGTGGATATATTTTTTCCATCTTCTAATGCTTTTTCTAGCTGCACTTATGTAATAAATATACCATTAGTTAATAATAACTTTTTATTACCCAAAAACTTGGTATATCTATCAAGCACAGAACGCAGGATATACAATTATAAAGAGTGAAAGATAGGTTTTAGTTTGACCTTGAACACATTTTAAAGTTTTACTGGCAACTATTAACGTAAAAGCAGAAAGTCAATATTGAGGTTTCACTAATTGTGATACTTTGTATCAGTTTGATGAAGCAGTAAATTAAGTATTAATTGGAGCTTTTTGTACCCTGGATTTTCTCAGATTAAAACATGGTTAATTTGAGATGATTTCTTGGGTTAAAGCTAGTTTCATAACGATAGAGAAAAACCGAAAATGCTCTCTGGCTAAAATCGGAAATATTGAATATAAAAACTTGTATCCTCCCAAGAAGGGAAGTAAATACTAATATTCTTGGAGGAACTCTCAGCCTGGAAGTTCACTAATTTTGTTAAGTGTTTTATTCCAGGCTAATTTTTGAGATATGACATAATTGACAGAATATGGTGTAAACCATAAGTTTTAGCTAGTTCAAGCTCAAGCTAAGAATGTTAGTAGTTAACTTTTGACTTTGAAGTTAATTGACATTGTGTGAAATTTCTAGCCCTTAAGTTTATGATGAACTCTAACCTTTAATCCCGTAAACTTAGTATTTCTATCCGAAATATGTCCTATCCTCTGCCACCTCCAGAACTACCTCCAATTGTTGAAACTTTGCCTTCACAATCTGTAAGCCAATATGTTACAGATATAGGACAGGAAGTATCTACTCTAAATCAAAATCAATTGAGTCCGATGTCAAAATTTAGCCAGGTTGGAGAGGAAATCAAAGTATCTGTAAAGAACACTTTCTTAGGAGAAGAGTTCAGAGAAACTGTATTATACAAATTTCCTCAAATTACCTCAAATTTTGACCACACTCAGAAAATCAGTCCAATTCATACAACCTCAGCTAATCTTGGACCACCAATAGAGATAGAGATATCATCAGCACCGAGAATTTCTACTCTGGAAAGCCAAATCAATTCAGGTAGAAAAAGAATATTCTCATCCATCTCGTTCTCAGATTTCTCAGAATATGCGCTCTCTGAAAAAGAGCCAGAAAATAATCAACTAACAAATTCATTTAGTCTCAATAGTAGAAAAATATTAGAACGTTTCAATCACACAAAACAACTAATTCCATCTAAATTTGAGATAGGGCAAACTATCAGAGAAAACAACACGCCAAAACTACCAAACCTTCCCCAAGACGAACAACCCATTAGGGAAACTGAAACCCCAGACTCAGAAGAGAATAAAAAAGAAACTCAATTTCCCACAACAAAACCAGAATCTCAAACTCAAGACTCAGAGAATAAAACGGAAGATAGACAACCTCTTGAAATACCTCTACCAGCAGATGTAGTAGAGGTAACTGCAGACCGCCAAGAATATAACGAGCAACGGCGACTTATTTCTGCAGTTGGTAAGGTAACAGTACGATTTAGTCAAGGAGTAATTAGTGCTGACAAAGTACAAGTTAACCTGACAACTCGTCAACTGCTAGCTATAGGAAATGCTGTTTTTACTAAAGCAGAACAAGTCTTACTTGGGGAACGTATGGAATACAACTTTACCCTTGACAAAGGGTTAATTGAGAAAGCAAGTGGGATTATTTTTGTTGGGGATGCGGAGCAAAGCACTTCCAAGTCTTTACCAACTACAGAAGGAGTAGGAGCATTAGAGGCAATATCCTTGAGCGATCGTATTGCTGCTACTCAACCTCCAACAAAAGTGAAAGCTACTGAAGGTACAAAACTTAGATTTAAAGCTAAACTAAAAGCACCAAAACAGTCAGGGATAGTTAACAGACTACGCTTTGAAGCTGACCGTCTCAACTTATTAGGTGCTGGAACTTGGGAAGCTATAAACCTTCGATTAACTAATGACCCATTTTCACCTCCAGAGGTGGAATTAAGGTCTGATCGAGCTATACTTAAACCTCTATCTCCCTTTCAGGATGAGTTGATAACGAAAAAATCCCGATTAGTATTTGACCAACGTTTTAGTTTACCACTGTTTCGTGAACGAACCGTTATAGATCGCCAGCAACGAGACCCTCTCCCAATTCAAATTGGTTATGACCAAGATGATCGAGGTGGTTTATTTATTGAAAGTACATTTGAACCTCTTCTCCCAGGTCCTTTGCAAATCAAAATAAGTCCTCAATACTACTTGGAAAGAGCATTTTTGGGAGATGAAAATGACTACCCTATAGATGGTAATGTTTTTGGTCTCAAAGCTTCTGTAAATGGTACCATAACACCCACAACTCAGGTAGAGGGACGTGCCACATTTCTGACCTTTGAAGATTTTCCAGATTTGGAAGAAAATGACTTTCGGGGTAGTGCTCGACTTAGGCAGTTTTTCCAAGGTTACAATTTGACTGGTGAGTATAGTTATCGCGATCGCTTATTTAATGGTAGTTTAGGATTTCAAACTGTTCATAGTAGTGCAGGTGTTGTGTTAGCTTCCCCTGTAATAACACTAGGTGAAACTGGTGTAGAATTTAGTTTTCAGAGTGGATATCAAGTTGTAAATGCGAGAACAGATCGTCGAGAGTTGTTAAAGGATATTCAACCATTTGAACCTCTACCTAATGATAAAAATGATGATGATAGTGATTCTAGATCGCGGGCTGATCTTGGTCGTTTCCAGAGTGTAGTTTCTCTGAGATACCCACTAACTATCTGGAGTGGTAAACCATTAACGGCTAATGCAACTGAGGGTTTGAGATATACCAGCAAACCAGTAGTTCCGTTTTTGCAAATGGTGTTAGGACTTACAGGTGCTACTAGCTTTTATAGTAATGATGAAGACCAATCTTTTGTGCGTGGAAGTCTTGGGTTTACTGGACAATTTGGGCATTTTTCTAGAGACTTTTTTGATTATACTGGATTTAACTTAACTTATAGTCAGACTGGTCTGAGTGGTCAGTCACCTTTTTTCTTTGACCGGGTGGAGGATACAAATGTGCTCTTATTTGGTTTAGTCCAACAAATTTATCAAGGTTTTCGGGTTGGTTACCAGAGTGGTATCAACTTAGAAAATGGTGATATTCTTGATGATAGAATTACACTAGAATATAGTCGTCGTACTTATGGGGTGGTATTAGTTTTTAGTCCTAGACGACAAACTGGTACATTTAGTCTCCGGATCAGTGACTTCAACTGGGAAGGTGGTACAACTCCGTTTTCTGGGGAAGATGTTCGACCGGTTGGTGGTGGTGTAGTTCGTTAAATTACCTATACTCAAGCATTGCTTGGATATTGCATGGGAGACGTTGCTTCCGGCAACTAACTAGAGATGATAGCATATTTTGTGTTACAGAAATCTTAGCAAAAGTACCCCTGAAAGGTTTATCCCTGATCAGGAACTCCTATAAACTTTTTATGCCATAGGGAGGCAGTAAGGACAATGATCGAAAAAATTAAGTCTGGCATAAAAAAAATGTTTTTTTAGAGTGGTTTTCAGCAAATTTGGAAAACACTTCTTAATAACAAAAATCCTTGTAGGGATGTTCTATAGAATCTTTCTACAGTTGTCTGTCTAAGTGGTACAGTTGACGAGAGTGCTCCTACTCCTAGCCTCTACTTTAAGTGCCGTATGTGAGAGTTTCCAGCTCATACGGATACTGATCACTAAGGTTCCTTCCAGGTTAGGTTCAAATACAGACCTCTTCGCAACTTGATATCAAGGGTTCTAGAGTAGGAAACTTATACTCGGGTACATTTTAACCTATATTCAATTAAATCTCTAAATAATATTAGAGAAAAACTTACTTTTATTAATTTTAGTTAACCAGAAATAAGACCCTTAAGTAGGTCGGTGTTGAAATTTATTGCTATGTAAAATAATGTAAATTTACCTCCAATAAACTGTGTAGAGGAGATTGAATTCATTACACAAATCTTAATATAGCTAAGTCTTTTTCATGCCTACCTACTTATTAAACAATTTATTAATCGCTTTAATTCCTTTTCGATAATGTCGAAATTTATGAGAATTGAGTATCATTAAAATTTCTACCAATTTCCAAACAAAATCATCATTTACTGCCCAAGGAATACAAGATAATTCGAGCAAAAAAACTACTGTGTTTTCTTTCTTTTCTACCCTGATCATTGATTCTTGATATATATTCTTTGAGACCTTTATTTTTAATTTTCTGTGTCAAGGTTGTCCTCATGTATTGACTCAAAACCGCCATTTATACCCAATAACTTTTGATTGGCCAACGAGTCGCACATTGCTCCAAGTATTAAACTCTGATTTAAAGAGATATAAATAGCGCACGAAATATTATCCTGCTTTACAGAAAACTCCTTTCACGGTGAAAGGTAATGCTATACTATGCTCTAAGTAGTTAATCTAACTGAGAAGAGGTTAAATGTTGCACCAATGACAGAAAAGCCATTAACATCTGCTTTAGCAGAGGCTTTGTTAACAAAGTATGATTTTGACCTGGGTGGTGAAACTTCTAAGCAGCTTATTGCTCGTTGGCAGAAAAACTATCAAGTGGAGTGGCTTTCTTTAGCAGTTATTGAAGCATTATATCTTGGACGTTATAAGGCTATCTCTGTCCAGCAAATATTGACATTATGGGAACGTCGTGGTCAGCCTATTTATCATTTTAACTCTGAATTTCAAAATATTATCACTAGAAATGTGATCACAAATTTTACAACTCAGATAGATACTCCATCTTTGTCAACAAAAACAAACCCTAGCTTTTTAGAAGAAAAACTAATAAACCATTCTAAACTTACTTCCCTACCTTCTAACCCCTTTGAACCAAACTTGAAAAATAAAACTCAAAATTTAATGCAGCAGCAAGTCCCAGTCGAACCATATCAGAACAAGATTAAACACACTGATTTTTATACTAAACTTAAAACAGTTCTAAAAAAGAGTCAAGCTTTACAATCATATCCCAAGGAATTGGAGCCAGAAAATGATAAGTAAAAAATGAAATGGCTTTGTTGCATAAATTTAGCGATATAGCAGCCACCACCATCCTCCGCCAACGCCAACTACTCCCCCAATGGAAGCAACTAGATTTCAATCTTGTAACTTTTAGGTTTATCTATTTGAATCATTCGGTTTAACATTGCACATTGTACAAATAATTCTACTGCTTGAATATCTCTGTTGTCGTCGTTGTAACTTCTCTCCAAATATCATTTTTAGTCCTTACATAGTTGTTTCAGATAAGGAACGCGATGGTAACAAATTTCACGTTTCCATCCATGCTCGTCCCACTTGCCTTATCCTGTCTTAAGTTTTCATCCCGTGGATGAGGAGTTTCTTGAAAATTGCTATGCTCCCAAATAACCACATCTTTTCGTGGAATAATTGTTGCTTTCACTCCCAACTGACTTGCTTTTTCATAACACTTATGTTGATCTTTTACTCCATCGGCTCATACTTGGACAATATCACCTTCATGAACCTCGCTGCGCTCTAGATCACCCTCATGCTTGCTCATTAGCAACATTATTAGTTGTAGCTATTGCTGTGAGAATCTTTCCTGTAGCTTTCCTTCGGAATGCTGCGCCAACATTTACACCTAGATATAACTTACCCCATATTCTATGTTTACCAAAATCCGTGAATCCTAGTTTTCCATTCTTCTTCAGGTGTAAACTTTGACTCCTTTAGGATCTACTACTAAATGAATCCCTTCTGTGGTTAGCATAACTGGTATCATGATATTTGATTTGGGGGACTCTACGGAAGACAGTGCTATGATCTGGCACAGGTAAATCTAATCCCATCAAGTGAAAAATAGATTCTATAAACCCTTGTGTTTTTCGCCCTGGAAGTCTAAATAAACAACTCAAAGTTACTATTAATTCAATTATCAAATTATTTGTATTATTAGATGCTCCTCTAATTCCACTTTTTGTTGTGTTGATTGACCCACTAGTTTATTACCTCATAAGGTGAGCCCATATGTCAAACTATCTCTTTGTTTTAAAGAACTATTATACTCTGACCAGTTGTTAAGAGGGTATTTAGACTTTGATTTAAATTTGGACTTGGACTTGGGCTTACTTATATTTACTTTTATGTCACATATTATCATTTTTACACTATGGGCATCCGCAGTGCAAAAAAGCCTTAGGAAAACCACAATGTGTAGAATCAAGGTGATGTTTTAGGGTAAGTGCGACGAAGAAAATTGGATAATCAGGCAGTGGAATTATTCCTATAATATGCCATACTCAACCGTATGATTCAAAAAATATCGCTCAATATCTACATGGGTTGAAATCTAAGTTAACTCCAACTAACAGGTTTTTAGTGTTTCCCAGGGCGATATGCGCGTGTGGAGCAAATTCAGCAGCTATATTGCAACCTTCATGCAATAAAGCTACTAAGAACTATAAAGGAAACCATTCGAGAATTATTTATGAGGATATGGTCATGTTTTGATGTTTTCTTTGTTAACTATTACGACTATTTATATTACCCCATTTTTCCTTCAATTGATGAATCTTAAAAATGCTACAATTAATTAAAGTTTGACTCAAAATCCTAATCAGTGCAAAATATAGTGTTGATTTAGAATTAATCAGATTAGTAAGTTAATGAACATTATTGATTTTTTTGAACTGAGTGCTGGTGAATGGTTTTCCCAACGCACAATTCACAATTTGGTTTCTGGGGAATTACAAGCAGGTAAATCAGAAGTCAATGTTGAAATATTGGAAAAAACTGACCCGACATTAATCAATTTGTGCGAACAAAATCAGGTTGACTCTAGTGTAACTAAATTAATAGGAGTCAAGATTAGCTGGAATGGTACAAATAATAAAGGACAAGTGAAAGATGTAGGTTCAAGAATGCTGATAATTATTCCTAATTTTGACGACCTTAACCAAGGTCAATTATTACAAAATAGAGGAAATGGTAACAGCCCAAAAATCAGTGGTCGCTATATTATGGGGAGTGATGATGTTCTAATGTTGACTACAGAGTCAGAGGGTTTGTATGTGGAGGAACGTTTCTGGTATTTAATACCTAATTTGCGGTTACGCACCAGTGTGGTCAACAGGCCACAGGGCTTTAGTTTAGCTTCTTTTTGCTCGGAAATTCGCAGAGTCAAAAGTTAAATGAGTGCATGTTTTTTTTTGAATACCTATAAATATAAAGGCTTCAGAAGTTGGAATATACAAAATATTCCAGTTATATCAGAATGAGGTAAAAATATTTAGTACCTTGCTATTAAAGAGTGAGGTTTAAATAAAACTTTTGTGGTATGGGTATCTTACCCGCTACTTGTATGCCTCACTTCTAACTGGGTAACAAGCTAATTGAAAGCCATATATAGGGATTTGCGTTTAGGAACTCAATAATACTTCAATTAAAACAAAACCCTTATTGATATAAATAGGGTGTAGTGTGAGGGCTCTGACCTCACAATACACCCTCAAGGAAAACACATCTAATTTTTTTTACAAATGACTAAGAAGATAACTTCAGAAGAGACTATGCGATCGCGCAACAAATAACTCTCAAAAAATACCAAAATTTTCAAATCACAGGATGACAAGCGCCTCAAAACTATTCTGGGAAAAGGTTGAAATATTGTTCATGAAGATGGAAAATTGGAAAACTTTTTGATAATAATAATTATTATTTTTTTTGTGTAGTTTGAGCTTCTCTCAAATACTTTCCCCCAGGGAAAACGTATCTAATTTTTTTTTACAAATGACCAAGCCAGAATATAATTTAAGAATAGGCTCTGGAATCATATGGGATACTGCCTACAATAATTACGAACTCTATAAACAGTTATAACCATCAAAAAAATCTCAACAATAATTAATATTATTATATACAAATCAGCTTTTAAAATAGACAGTTATGAATGATAGTTATTATCTAAATAATCTCAATCTTTAACAATAAAAATTATGAAAAAAATAGTATTTATGAGTATTTTAGTGAATTATAAAACCCCTGATTGGAGAGAACAAAAAGCCAGAAATTAATTGATATTATTACAATTATTATTTCTGATGTAATTTGTGGTGTGGATACCTGGATAGATATAAAATCTTATGGTAAATCTAAAAGTGAATGGCTAAAAAGTTTTTGAGAACTGCCTAATAGAATTACATCTCACCATACAGCGTGCACGAATTTTTGCACGTCTTAAGCCTATTAATTCAAGCAATTTTTTTTTGTCATAAATTAAGTCAGTAAGTCAAATAACTAAAGGAGAAATAATAGCAATTGATGGTAAAACTCTCAGAGGTTCTTATGACTAAAAAAAATCTCAAAAACCTATTCATATCGTCAGTACCTCGGTCAGAGCCAATTCCCTAGTTTTAGGTTGCCATTGTAGATAATAAATCGAATGAAATCATTGGAATTCCCCAAATTATTAAAGTTTTATCCCTTTATAGTAGTTACAATTGATACTTAGGGAAACCAGAAAGAAATTGTTAAACAAATTACACAACAACAGGGTGATTATGTAATTACTTTGAAAAAAAAATCAAGGTGATTTTTATCAAAAAGTTACTATACCTTCTCTCTATCCTGCCTCTTTTATTCCTTATTAACATATATTTTTGTATACCTTTATTTTTAATTTTTTATTCTTTAAATTAACTAATTTTCTAAGAAATAGCTATCAGTAAAATTCAATTATTTAATCTGGTTTAATTTGCTTTTGCTCCTTCAATATTGTAATCTCCACTCTTACAATCTTTGAACATGGCATCAATTCCTATTCTTTGACTATATACTTTATTGATTTTATATGATGACGATAAATTACTAATAATTTATTTCGATTTATTATTGACAATAGCAGGAGCTAAAACTAGGAAATTGCCTCTAACCAAGGCACTGACGATATGAATAGGTTTTTGAGATTTTTTTTAGTCATAAAAACCTCTGATAGTTTTACTCTCAATTGTTATTATTTCTCCTTCAGTTATTTGACTTACTGACTTAATTTATGACAAAAAACATTGCTTGAATTAATAAGCTGAAGACCTACAAAAACTCGCGATCGCTTTATGCTGACATAGAATTCCATTGGGCAGTTCTCAAAAACTTTTTAGCCATTCACTTTGAGATTTACCATAAGATTCTATATCTATCCAGATATCCGCACCACAAATTACATCACAAATAGTAATTGTAATAATATCAATTAATTTTTGGCGTTTTGTTCTCTTAAATCTGGGATATTATAATTCACTAAAATACTCATAAATACTCTTTTTTTTTCATAATTTTTATTGTTAAATATTGAGATTATTTAGATAATAACTATCATTCATAAATGTCTAATTTTAACGCTTATTTGTATATAATAATATTAATTATTGTTTAGCTTTTTTTGATGGTTATAACTGTTAATAGGGTTCGTATTTATTGCAAGGACTATTCCATCTGATTTTAGAGCCTATTCTTAAATTATATTCTGGCTTGGTCATTTGTCAAAAAAATTAGATGCGTTTTCCCTGGTATTTAATCCCCAATTGAGATTTCAGTTCAGCATCTCCTCTGGTATCCACGGCACGAAACAGGCAGAAATTTTTATTTGTAAATACCCACAGCCATTCCTTGATTCCTCTGGCAGGTCAAGACGCTTCATTTAGATGAATAGAAAGTTGTTCTGTACTTAACAGTTTTCACTTAAGATTATAAGATTTATGACCCAGATACTGACAAAAAAAGTGGAGCGTAGCGTTAACCTTATCCTATAAAGAAGAGCGTAAAGATCGTCTCATTTGTCATAGCCTATATAGTGTCTTTGCGTAAGTCCTTTTAGTCCTGAGATGATATGATATTAAATCTGGTAGCATTGATCTAATTATAAGGAGTCAGGAGTACTAGGGAATGCCCGTACAGAAGACGTGGAAGGAAGATAATTTAGAAATATTTAACAATTACTGAGGATAGAACAATGGAATATTTTTTGATACCAAATTATATCACATCCAGTGCTATCGTTTGTGTAAACCCAAGGGTAAATATCTACAGAAAATTTGGCATTGGTAAATTAAGCAATGAATTAAGCCGGAATGGGCACCTCTCCAAATTTGAGAAGCGTGAATCAACAAACGGATAGAATCTTTGAACATCTCAATACATTTTGAGTAACATAAGGTTTTGCGGCATAAGCGAGTTTTGGGATGACGTAAGCGAGTGTTTTCCCTTTCTACGCGATTCATATAGGTCTTACTTCCGATTTTATCTCCGTCACGGATAAAGCCTGGAAGCGACCGGATTGCCATCAGTAACCTGAAAGTAACACTTCCAAAAGCCTATCGCCTGCCATAGCGGTTGAAAAGTATCACCGCTGTGGTTTCCGACTACCCAACCCAGGATGCCCTGACGGAAATGGTATACCAGAGTCCACAACAACACCTTGTTTTTCTTATCACTAACAAAAGTTTCGAGTTCATGAAGTTCTCCTACTTGAGACAGTTGGTCTAGGTCATAGGCATTAGGTGAGCATTCCCTGGTGTGTTTGATCAAATTGATAATAGTTGGATATGTAACCCCTTTCACCCAGGCAATTCTTCTAATACCCATACCGTTAACGTATATTCTCAAAAACAGCCGCTTGACATTATCGCTGTATTCTTGTGGGTGATAAGGTTTAATGAACTGATGGCTACAAGCGACGCAAATATAGTTCTGCTTGCCTGGTTGATGGCCATTTTTGGGGATATGCTGACAGCTACAGTCAGGACATTGTATCGGTTGATCTCTCACAGTTGTTAATGACATTAACCATTATAAACCAACAAGCTATTTCAAAAAAATAGCTAGACTTTTTACAAAAAGTAAAACATTTTTAGCTTTATTTTATAATTAGAAGTAGTTATACCTGAGTCTACCCCCAGTTCACTCTTAAAGTAGCTTTATCTTGAATAAAAATTTCTTGATTTTCGTCTAGCCAGCAAAAAAAATTTGTAGGAAATACCAGGAATGAAATGCTTCTAATATCTCTATAAAATTTGTCAATTATTTGCAGGAATAACGCTTTATTACACCTACCATTAATTGTTGATATGAGATGAAAGGATATGAAAAAAAAACTAGAATACAATGGCGCATGAAACTCGTTTTATCTCTAATTTGATGTTCTTTTAAACCCAACTTTATCTTAGCTTTTATGTAATTTTTTTCAATATAGTTTCTATTAAGATACTTTGTAAGGATCAATGCTCTAGATACACTTTTATACTGTTTATTTGTAATTAAATAATCAATTTTGCTGGTCTCTTTTATATAAATACTATTAATGATGACTGCTATAGTTCTATAACCAGTTAAACCTTTAGTTTCTAATTTTATGGTAGCTACCCAAACTTTTTTAGGTATATCTTGTTCTAATGTTACTGCTTGAAAAGCATTTTTAGATAAAGATAAGGCTATTTTATCCAACCTTTTTTGTGATTGTTTTTTCTAGTTTTTTGATTGATAACATTGACTCAAATATTTTTAGCTAAACTCCATATATATACTTAAGTTATAATCGTTATAATTATTGTAAAAATGAGTAATTATTTCCATAAAATCTATCTAATAAAACTATGTCTACTCTATATTTAATCGACAAAGTTTTTTTTACTAACTTGACTACTAAATCAGATTTTTTAATAAATTATTTATCATCTTGACCAGAGGTAAAAGATGATAATTTTTGATAAATTATACATCCAAAAGTATACTTATTACTCCATCATATAAATAGCTTCTGACTATCACTAATCCATTGTCTGTTTTACCTACTTTTTTTATCACCTGTTTTTGGTCTTATATCCTCAGTTTCTCTTCTTCTGTGTAAGCAAATATTGATAATATTACAAGCCATCTTAAAGATAGCACTTGCTTAAGTGTTACTCATCCCATTATCAATAGCATTAATAACTTTTTGTCTTAAATCGTAACTATAAAAAGCATGCATAATCTTTTCGATTTTGATTTTTTGAGCATTATGTATTAATCTTTACTTCGATTGCTATACTTAATTAATATCAAGTTTATTTTACTACAATATATTGTTAATTAGACTTAGACAATTTTTAAGCACAAATATAACCATTACCAGCTTAATAAGAGGCAAATACTTTTATATTTTAGTCTATAAAATGCAATACATCGCTGCACGAAAAGTATCTATTTTTTTAGTAAAAGTCTTTAAAGTTTTTTTTGTTTATTGCTTTTATCATACCCCTTTCAACCTCTCCCACTGGATAAAAGTATAAGCACAAAACACCAATATATAATGACTATCTTGTCTCCATTTATCTCTGAGATGATATTCTGTTATTCCTAACCATACTTAGCCTATCTCTCTGTGTGTTTAAAAAACCTCTACCCAATTCTCTGAGAATAGGTGGTCTTTACTATCCCAGGGTAAGCTCATCTAAAATTTTATTTACAAATCAATATTTTTATGACCTGCTTTCAATACAAGCTTTTCAAGGAATTATAAATATCACATAATTTTCATATTATCGATTTTTGCTGCTTCACAATTTGAATATATTTTCGTCACTAAATTCATCTCAAAAACAGTCAGGGTAATATGATTATAAAAGATACTATTTGTCAATGATTTTTAATATGAGCTGACCCTGTTTTATATCGCTATACAATGTTACTTTTAACGACTTAAAATTGATAATAAAATAATCAATGTCTGTTGCTTATTCCATGAACTAGTATTTTTATCCGATGGGGAAAGTTTTTTATCCTTCTAGTAGTAATACTGATCCGCGTGAATATTTTGAAAAAAATAATTTTGGGTTTTCCATTGGCTGGAAACAACTGGTAAAAATCCTTATCATTAAAGGTTTTTGCTAACTATTTTAGGAAGTTTTCTATTTATGTAACAATTCTCATAGCTATGAGGTAAAGTAACAACAATGGTTAAACTAATTGCGAATATCTTTTTGACTAACTTTGAATATAGCTGAGGTCATGGCATCAATTAAACCTTGATAATTTCTTACTTTAACTCTTCTTAGAATAGCTTTTGCTTTTGAAAAAAAGTTTTCAATTGGAGAAAATTCAGGTGAATAAGGAGATAAAAATAACAAACTAGCCCCAACTTCTTCAATAATTTCTATCACTATTTTTCCTAAATTGATTTTCCCATTGTTCATTATAAAACAAGCTTTATTTCACAGTCATAGGATTACTTATTTAACTATAAAAGTCTCAAAATTTACTCCAGCTGCTGCTCTATAAATATTTGTTTTTGCCAAAACTTTTTCTTAGGATATAGCTCCTATAATTGAGATATTTTATCCTCTGGATCTTTTCCCTTTTAAGGCTCTAGCATATAATCGAAGCATTCCCAAATTTACTCCTGATTTATCTATAAAGACTAAATTATTGGTCTTTATTCTTCTGATTATTTCCCAATACTCTAATCTCTTATATTCGAGTTGAGCATTTTCTTTTTCAGGTGCATACAATGTTTTTTTTGAGATTGTAGTTTAACTAGACAGTGAGAGTTTCCGGGAATAACTATTGCTAGCTTTTGCTTACAGCTATCTCAAGGTTAGAAAATTATTCAAAGTAATTATAAATACTGTAAGCAAATTCTTATAATACTTTCAGCTGTTAAAGCAAATATTTTTTTAGGACAACTTTGTACTCTCAAGTAGTTTCACTTTTCAGTTATCCAATAATTGTACTTTTTCCTACTTTTACTCCTGTGGCTACTTCCAGTAATTCCCATAAATTCTCATTAGTTGTATCATTATTTTTCTCCATTATTTCTACTAAGATTACTAATTATTCACTATTAAGCTTAAAAGGAGGACTTCCTCCTTGAGCTAAAGGTTTAATATCTTCAGTTTATTGATATTTTTTGGTTAAGGTTTGAATAAAACTTTGTCTGACTCAAAACCTATGATCCAGATTGTTTATAGACATTTTTTCCGCAGCCACAAATTTATACAATTTTTTTTATAAAGTCTATAGAATAAGATTTCATCAGTTTCGCGATCGCTATAAAAATTATTCACCCTAGTTTACCTTATGACGATGGAAAAGGCTATATTTATTGTGATTAATTAATAATTATCTTTTGATTTTTTTGCTACTATTCCATTATAACTTAGTACTCTGTATTCGAGTTTTTTGATAAATGTTATGTTGTTACCATAATCTAGAACTATTAAAACTATTCCCTAACAATTACATCTGTTTAGGCTACGGTCGATTAACTTTATTCCTATGTCTGATTTTTTCTCAAATAATTTATTCTCTTTTCCTCTTAGTAAACAACTAGAATGTTGATATAATTCAATGTCTAAAGATAGACTTTTTTCCATCATAATAATATGTTGTTACTGTAAGTATTCCATCTGTTTTTTTTCCAATTTATCCTATATATAGTAGTCCAAGACCACCAGTCAACTTACCACTTTTCAAAGCACCGGAATCATCTAAAATCAAACAAAATCCACTTCTAAATTTGCTTTTATAGCGTTTATTGATAATTTCTATACCGTTTATTAATTTGACTAGCTTTCCTTGAAAAATTAGGTATAAAGTGATGTAATCTATTGTAGACTAAACTAATTAAGTCATTGGCCATTTGAGATAGGTGTTTTCTCTTCCTTTCCCCTAATAAGCCTGCTAAATAATCTTTAAAACCTTTTTTTTGAGGTAGATTCAACTTCAATCATCAAACTTTTTATACTATCTTTCAACTGAAGGGGGCATAGGAGTAGGAGTTGTTAGTCTTATCTCAAACGTCCTTGACATAAAATCCTTGTCAAGAAAGCATTATAGTCTAGTTTTGTGAGTTAGGTTGTGTAAGTCCCATTAATTAATGTAGTATGTTGACCTAATTTTAAGCATCATATCCAAATAACCAATACAATAATTGTATAGGAAACTAAACTGCAGAGTAATATAAATTGGACTAAAAAATCAGAATTGTAACCATCGTTCTTTCCAAAGACATTAAATTGTGGTAAATAATAAAGTTAAGTTGTAATAATAAACTTATTAGGATATACACTAACAGAGAATTAAACTGTAGAGTGCTATAAATTGGACTAAAAAGCCACAATTGTAACCATCGATCTTTCCAAAGACATTAAATTGTGGTAAATAATAAGATTAAGTTATGATACTAAACTTATTAGGATATACACTAACTCTGGTATAATTTAAAGGTACTAAACTATGCTCATAGAGATATTAACCCTGTTTGCGGGTGCAGGACTAGAACAAGCAACCAGTGTCACATGGCATTGGGCAAGTAAATGGGCAGCAAAGAAGGCTGATGAAAAGAGTCAGGTAATACAGACAGCATTACTAACTTCATATTGTAAAGCTTTGCAAGTAATTCGTAAAGAGTCTCAACAACTACCTCAATGGAAACAAGAGAAAGCTGAAATTCAAGCTAGATTAACAGAAATGGAGAAAGATGCACTCATGATATTAGATTTAGCACAGACACAGAAGCATAGAATGACTAGTATCCCTCAAGGTGGAGAAGAACAAGCGATCACAAAAACAGTAATGTCTAGACTGCAAAGTAAAGATAAATGGCTCAAACATGCTCCAAAAGAATTATCTTATTTAGTTGAAACTAGATTAGTATCAATTACAGTGCATCAGTTTCGCCACGAACTGAGAACAGAAAGCCGGGTATTTCAAGCCTTAGTCCACGATATGTTAGCTACAGCAGGAGAAGATGTTAGTCGTTTGCTTGATGTCACTAATAGAATAGAGAAAAGAGTAGATCAATTTGTGGGAGACTACCGTCAAGATATTGACAGAATTATTGTAGGTATTGGAGGAGCTAACTCCCACCTAGAACAGTTAATATCACTGTTAAGCAGACAGATGAAGCAATCTCAAGCTATACCTGCTGACTTTGCTGCTCTGATAGCGGATAAAACAGAAGGATTTCTCGGACGAGGTTTTGTCTTTGACACGATAGAGAATTTTATCCAAAATCAATCCAAAGGATATTTGATCATTGAAGCAGATCCAGGAGTAGGTAAAAGTACAATTATAGCCGAATATGTACGTCGCACAGGTTGTATTGTCTATTTTAATTTATTATCAGAAGGCAGAACTAGGGCTGAAGATTTTCTTAAGAGTGTGTGTACCCAATTAATTGAACGTTATAATCTTCCTTATGAATTACCATTACATCCAGATAATACCAGCAATGGGAACTTTCTGTCAAAACTACTGAATGAAATTAGTATCCAATTACTCCCTAAAGAAAAACTTATAATAGCAGTGGATGCTTTGGATGAAGTAGATTTAAGTAGTCAGAGTGGAGCAGCTAATGTCCTATATTTACCAGCAAACTTACCTAATAGAGTATATTTTCTGCTTACTAAGAGATCGGATCCACTACCATTAGTAGTGTCGGCGCCACAGAAAATTTTTGATTTAATGATCTATCCTAATGAAAGTTTGAAAGATGTTAAACTATTTATTTACCTAAGAACAAAGCGAACTACAGTTCAAGCATGGATTAAAACTAGAGGATTAACATTAGAAAAATTTGTCGAATCTATAGCTAGCAAAAGCGAAAATAATTTCATGTATTTAAAATATGTACTGGATGATATTGAGCAAGGCAGCTATAGAGATATCAGCTTAGAAAGTTTACCCCAAGGCTTAGAGAAATATTATGATCAACATTGGCATAGAATGAAAATGAATGTTAAACCATTGCCAATTACTAAACTAAAAATTATATATTTCTTAACAAAAACTCGTAAGCCTGTATCCTGTGGAATGTTAGCTAAATTTAGTGGAGAAATATCTTTGACAGTTCAAGAAATATTGGATGAATGGGCGCAATTTCTGCGGATTCATCAAACAGAAGGCAAGCCGGTGTATAGCATATATCATGCTGCTTTTCAAGATTTTCTCTACCGTAAAGATATTGTTCAGGAAGTAGAATCGTTAGTTGAAATTGAAAGTATGGAAAAACAAATCAAAAATAATTTGTTAGGAATGGTTTATAAAAATGGTTAGTATTGAAAAATAAAAAGTTAGAATCAATAAGTCATAATCCAGATTTTATGGATTAGGAAAAGTGTTAAAAAACCACTATAAACTAATACTAAGTGTCAAAAAAATGCGGCCAGTAGTTTCAAACTTTAGATGTAAAAGAATTTCTGGAAATTACTAATCACGTCAAAGTTTTGATCAGATCTTGTCTAAGCTTTGACTTTTAAGTTTTAACTTCGACGAAACGTTACAGTATCTACTACCGAAAATTTAGAGGAAATTTAAATGGGTGAATTTAGAGAAAATTTAGTTCAACTACCTCTAGAAGATCAACGCTATCTTTTAGAAACTTTACCTGGTTTTCTAGTGAGTGAATGTGATACAGAACAACTGCATCGCTTGCTAACAGATTTTGATTTTCTTGAATCAAGACTATATTTATTTGGAGTAGAATATCTACTAAATGATTATGAGGAAGCGATGCACTCCGATGCGTGGATATCAGGTGAAAAACTAAAAACCCTAAAATTCATTCAAGGAGCAATTGAACTATCATCTCATATCCTAGTTGAAGATAAAACCCAACTAGCAGAACAACTGTGGGGAAGACTGCTATCCTTTGAAATACCAGAAATTCAGCAAATGCTACAACAGGCAAAATCCTGGAAAGTAACTTCCTGGTTAAGACCAATTGCACCTAGTCTGACACCACCCGGAGGAAGACTGTTACGAACTTTTACTGGTCATAGTGGTTGGGTAAATGCAATAGTTGTTACTAGTGGAGGAATGGTAATTTCGGGTTCTTCAGACAATACTCTCAAAGTATGGAATCCTGAAACAGGCAAGGAAATTAGTACCATTACTGGTCATGCAGCGCGAATTAGAGCGATCGCTTTACTAGATGATAAGTGGGTAATTTCTGGGTCTGATGACTTCACTATCAAAGTTTGGGACTTAGAAACAACAGAAGAATTAGTCACCTTGACAGGTCATACTCGAGCAGTTAGAGCAGTGGCAGCGCTTTCTGATGGTAGAGTGATTTCAGGTTCTTCAGACAACACTATTAAAGTCTGGAACCTTGAAACACAAAAGGTGGAAATGACTCTTAGAGGTCATCAAGGTTGGGTAAATGCAGTTTCAGTATTGTCTGATAAAGAAATTATTTCAGGTTCATCTGATAACACTATCAAAATTTGGAGTCTGGAAACAGGAGAGGAGCTATTTACACTCAAAGGTCATACAGATGGTGTGAGAACTATAACTACACTTCTAGAAAGACAAATAATTTCTGGCGCTGCTGATAACACAGTTAAAGTCTGGAATCTTGATAGTAAAAAAGCAGTTTTTACATTCAAAGGTCATAGCAAAGAAATAAATGCAGTAGCAGTAACTCCAGATAATAAACGAATGATTTCGGCAGCTTCCGATAATACTCTCAAAGTATGGAATCTTGAAACAGGAGAAGAATTATTTCCTCTCAAAGGTCATACTGAATCAGTGTATGCAGTTGCAGTTTTGCCAGACGGACGGTTAATTTCTGGTTCCGATGATTTTACCCTCAAAATTTGGAGCCTTGATACCTCTGAAGAATTTTGTCCTATGGTTGGACATACTAATAGAGTGAATGCAGCAATAGTTTTGCCAGAGCAACAAGTAATCTCTGCTGCTTGGGATCATACAATCAAAGTTTGGAACTTGAACACAACAAAATCAATTTATACTCTTAAAGGTCATACTGATCGGGTAAATTCTGTCGCCGCATTACCAAATCAACGGATTATTTCAGCTTCAGATGATAATACTCTCAAAATATGGAGCCTAAAAACAGCAGAGGAATTATTGACTATTGTTAGTGACAATAGATGTATTTTTGCTGTGGCAGTAACACCAGATGGGAAACAAGCGATCGCTTGCTTATCTGACCAAACTCTTAAAGTCTGGAATTTAGAAACATTGGAGGAAATTTTTCTCCTTAGAGGTCATACTGACTGGGTAAGTGCAGTTACAGTAACACCAGATGGTAAGCAAGTAATTTCAGGTTCTTTTGACAAAACTATTAAGGTTTGGTCTTTGGCAACTAGAAAGGAAATTGCTACATTAGTTGGTCATACTGGATGGGTAAAGGCGTTAGCAGTAACACCAGATGGTAAGCGAGTGATTTCAGGTTCTTTTGATAAAACTATTAAAGTATGGTGTTTGGAAACAGGACAAGAACTATTTAGTTTAAGTGGTCATACTGACTGGGTAAATTCCATTGCAGTTACACCAGATGGTAGTTTGGTGATTTCTGCTTCTGATGATAATACTCTAAAGGTTTGGGACTTAGAAACGCGACAGGTAATTGCCAATTTTACTGGGGAGAGTTCTTTGGAATGTTGTGCTGTGGCGGCAGATGGAGTACAATTTATTGTGGGTGAGGCTTCCGGACGAGTACACTTTTTAAAATTAGAGAATTACAAAAATCAGGTATGATAGCTTAAGTAAAAAGTAAGGGGGAATAGCTATTCGCCTATTTTTGCTACGACTAAATTTGAGAGGAGTGAGAAGGTTCTAGCTGCCCAGGCAATTCATATAAATATAACTTACATTCGGTACTTGACAATTTAGTATGAAATAAGGAATAAGGAATCAGGAAAAAATTATAGTAGTCCCATAACATCCATCCTGAATATATCGGCGTTGGTCAATTAACATAAAAAATCTAAATTTGGCCAAACATAAAATTATTTTTAGTTAATAGTTAGGCAATCGCTATTCAAGCAAAATCATAGCCCAAATAACCAACGCCATATATCCATACATAATATGTGTAATTTTTGCTATTGCTTTAATATTCTTAATGCTTGGATTGCCAGTAAGATAAAACCTACAAAACCTAATGCAGTAAGAATTTGGGCTACTAAATTAGGTGTTAATATTTCACTCATAACTATAATACCTTTAACAAAGTCAGAAGTCGGTGTTGTCTAAGTCAAAAGTCAGAAGTTGTTTTTGTTATGGGGATGAGTGAGCAACCCTCTAAAAACATTTCTCCTCGACCAAGACTAAATTTTTATAGGAATTTTGAGATAGAAATTGAATTCATATATTTTAATATAATTAGGGATTTTCAATACTTTTTATGACTAAATTATAGCAGATTTGATTATTTTATTGGCGGGAATTTTTGTGAATAAATAATTGTTTTTTTCCCAAAAATTTGATTTATTTATCATCTTAACAAAGATATAATCAATGGTAATTTTGAGTAGTGACATAATGAACACTGTTGTTTTTACGACTAAGCACTTTACCTCATAAAACTCAACTATGGCAAGGCTTATTTATTGATATATCGCTCTCTTTGTGTCAGCAGCCATCATAAAAAAATGGTACCCCACTATTCCTACTTACTGTTAAACATATTTAAGTTTGGCCGATAGTTGTTCTTAGTTATCCCTTTGTAATTAATATCAGTTTTTCCTGACTGTATTTTGAATATTTTTGATGATTTTTAGTAGTTTCAATAGTATGATATTAGAGCTGAAAATTAAATGATAATAATTTTGAATCTAAGTGAGTATGTTTTTTATCGTTTTTAAACGTTTTAGTAACTAATTCTCAAATTTTTACAAATTAAGTTTTCAACCCTAGTTGATAGATATTATCCATTGATCTACTAATTTTATTATTATTTAAATATTCACTTTTTATGTTTGTTCCTAAGAATTTTTCTAGAGTTTTGTCTTCAAAAAACTAACTCAAAAAGCATAAAGGACGTGGTCCGATTTTTAACAAGTTAAGAATTAAAGCTTTAATTACTTATCCTGATGTAATTTTTTCTGAATTATCTACTCCTAATTTCCGGTTCATTATTTCCACAATTCCTATCTCATCAATTAGTCCTGCGACTATTTCTAAGTGGTCAATATTTTCAACTGTTATACCATTTCTCAAAAAGTTTTCTGAATTTGCCAATAGCAGGAGACTAACTCCTAAGCAAAACAGTGGATGGAAAATAGGGAGTTGGGTTCAAGAGGTTGCATAAAGGCATCCGTGCAGGATAAGAAAAATTCATATAATTTGCCTATAGTAAAAGCAAGGAAATAATTTATACAAGAGTGTGTTAATTACTTTAACTTCTACAGTGTTACCTCAGTATAGTATTAATACATAGAAATTGGTATGTTTTTTTTATTAAAGATATTTTTTGACTAAAGAATAACGTGATTATTAGCTTGATAATCTCACTTAAAGCTACTAAACACCATGAATGATTCTACTTAATAAAATTAAATAGATAGATTTTCTGTAAATTTTTGTAATACGAATTGAATTATAAGATATGGGATGAATATTGTCCCTAAATAGTAGAATCAAATGTACTGATTTGGCTAAAGGAATTTATATTTTAGAATTAATAGTGTTTTTTAATTCATGATTCATTAATCCAATTTTTCAAACTTTATGCTAAAAACAGAGTTTAGCTACAAATTTCCCGAATCTAACCATCCTATAGTTAAGTCACTATTTCATCACAGTGACCAAGAACTATTAACCTTATTTCAAAACTATCCAGACGAGGGCAAATACTTCGTCACTATTTTCTGTCGCTACGGAATGATAGTTCAAACTTTAATTCAACATTCTATGCGATCGCCCGTCCAAGCAGACTATCTATTTGCCCAAACCTGGGAACATATATTTTACGAATTGCGTGGCTTAGACTTACGAGAGGGAGTAGATCCAGAGACCGGAAATACCACTCTTCAGAATTGGTTAATTAATGTTACAGGTACTACTATTAACCAAGTAGAAGTGCCTCCTGTGGAGTCAATACGTTATTCTTTAGAAATGGCCCCACCCCCTTTATGGTGTTATGTAAGACTTGTATTAGCCCAGTTAAAGCCACTACTACGCTTGATTACATTGATGTTTCAAACTTTCCACTGGAGTGAAACAAGAATAGCAGCCTATCTCCAAGCTGAGGGAGAAACCATTTCACCTGAAGAAGTAAAATCTTTACTAGAACAGGGGTATCATGATCTAGATTCTAATTTACCAGAAGATATTAAAACTATCTATTTCAATGATGATATTGAGCAAGTTAGTATAGGTATAAATCAGTTTTTTAAGGTTCCAAAACAACCAGAAAATTAAGATATAGTTTAGATTCTAAGGTTGCAAACTTCATAACTGAACTTAAGAGTTGCGCTGCCACTGTACTGGTGAGTGCTGACAAAAAAATGAAGTTAATAGCTTCTCCTTTTAAGGTTCAGAAAAAAAATCCAATTCATTATTGAAAGCAGGAGGCTTCAGCTCTTGGTACTGTTAACTAATAACTGATAAATGAAATGACCGCTTCTTTAACCTAGTTCAAAGATATCTGACCTTTACCACTAATATTAAGTGAGTTAGTATCTAAATCAAAATCTTCTGTAGGGTGAAATATAACCTCTAATACCGTGGGAGAAATACTCTGATAACGTACCAAAATCAACCCACCATCAGGACGTTGATAGGTTAAGGTTAGTGGAATTGACAGTTTAGATAATTCCACCACTGAAGTTCCCCCTAGAGTCATATATTGGCCACCTATTACCTGATATTCAATTATGGCACCGGTCTGATTAATTAATCTGAGAGTAATTAAACCAAGGTCTGACCTGATCCTATCAGGTGGAGAGTCAGTAGTCTCTGACTGTTGGGTAGGAGACTGACGGTGAGTCGGTTTGGTAGTCTTAGGTTCGACCTTTACAGGTTTTCCTCTATGATTAGATGAATTAGAAGTATCCTCTTGCTGATTAACGATAGGGGGCTTCGTGTCTGGTGGAGGCCCTCCAGCTTGGGAAATTGTGATTATCATTAAATTGCTACCAATAACACTAATAATAGAGATTCTTTTAATAAAATTAGAAAGAAATTGGATCATCATCTTGTCGGATATGGAATTAGGGGTTATGGCGCTACGCGCAAGTCAGATGTCATAACTCAGAAGTAATCTCTGACTAAGTTGGAGCGTTTATAAAGATATTTAACCTATTTGTGCAATGCTATAACTGTAGAATTTAAACAAACTGATGTTAAGCCTAATTTAAGTACAGTAGGAGTTTCTAAATTTATAGGGAATTGCTTTGCTCGCTCCTTAGACTTACGCCCAAGTCGGGATATTATATCTTTGACTAAAAAAAACTAAACGGCTTTTCCATTCATCTTCAGCAATTTTCCTCAAGTATCATTTTAGATAAGACAGTCTAAATACTTAATTTGTTGCTAGGGGGTTGGCCTAACTCTGATGTAAAGGTAAAATAACAGTGGCCATAGTACCTACTTGAGGACAACTTTCAATAGATATTTGGCCACAATGATTTTCGACTATAGCTAGAGCGATCGCTAACCCTAAACCTGACCCCACTATACCGCCATGGGAACGAGCGGAGTCTACTTGATAAAAGCGATCAAATAAACGAGACAAAGCTTCAGTCGGAATACCGATACCATTATCCTTAACCGTTACCTGGAGGCAATCGTTTTTAATATTTTGACAACCTCTAAAAATTACCCCACTATTCTTAGAAGTATTTCCTAGTTCTCCATCCTGAGTTCTCAACATTGGCTTTTTAGCTTTTGGAAGGTACTGCAATTCTACTACTAGATGACCACCAGATTGAGTATACTGCATACCATTACTAATCAAATTTGTAAATAACCTAGCTAATTGTTCCCAATCTCCTATAAGTGTAATATCTTCCTCAAAAATAGGATGTTTAATAATTTTAGAGTTATCTATTTTGCCGTGATGTTTATAGTTTAATGTAGAGTTTTGATTAAAGATTGAATTTTCTCCAATAAAATCAGGTAGAGAAATTTTTAATTCTAGATTTATACCTTGAGCAGTAGCGATCGCCTGTTGTTCTTCTACTACTTCCATCAATAAGGCTTCTATTGGTACTGGTGAAAACTCAGATTGCACCATTCTACTATCCTGACGTGCTAAAAATAGTAAATCATCTACTAAGCGCCCCAAACGACGGGTTAAACGTTCAATAACTTGTAGTTGTTGCTGATGTTCAGATGATACTAACTTGGGGTCTGCCAAAGCTACCTGTACATTAGTTTGAATCATTGCTATCGGGTTTCGGAGTTCGTGGGAAGCATCAGCAGTAAATTTTTTCAAATGTTGATAAGATTCTCGTACTGGTTGTATTGCTAAACCAGAAAGTAGCCAGCCGATACCCCCCACAGAAATTAGCACTAAACAAGTACCAATACTTAAGTCTAGCATAAGAAGGCGAATTGGTTTTGTCACCTCAAACCAAGGATGACTCACTCGCAAATATCCTAAGACTTGACGACCTACTTCTACTCTATCTGTCACTTGTCGTAATAGTAAACTATTATCAATGATTGGTTGTAATGTTTCAATTTTTCCAGAGTGGGGAATTATTCTTACTGTTTCTCCAATACGGTTTGAATGTATGGGAATATTGAGAGGTTCAGAAAAGGTTGACCAAAGTAGTTCTCCTGTAGGACTAAACCATTCAATATCAATGTGGTCATCTTCTACAGTGTTAGCATTATCTCGAAAGCTAACTTCTAGGTTGACACGAAAATTTTCACTGTTTCCAATGGGAAAGTTGGGGATAGGTTCAATAATAGGTTCGATAACTAGGGAGCGCTCTACTATTTCTACCACATGGAGCAATGTATCATCTATACGTTCAATTAGGGTACTACGAAAATATATATAAAACCCAGTGGTAAATATTAATAATAAAATAGCTGTGACTGTAGTGTACCAAATTGCTAAACGGCGACGAGTTGTTTGAAACATAATTTATTTTTCAGTAATTTCAAATGTACGAGAGTGAGGCACTAATATATAGTGCTACACATCAAACTGATTTATGCGATCGCGACAACTGATAACTGATAACTTAATATTGGCCATGCCAAAAAGTAGTATTTAGGATAAGATAGCTCTAGTTGAAAAATCTTAATTAAATATTAAATTATGTTTATATCCTCTGAAGGTATAATCAAGCTTCAAAAATACTTTAAACAAAAGGTATTTTTTGGAAATGAACCAACACCTGAACTTATAGCCATACTGCTTGTTTACTTTGTCCAAGGAATTTTAGGGTTAGGGAGTCTCGCTATCAGCTTTTTTCTCAAAGATGAATTGGCCATGACTCCGGCAGAGGTATCAGCAATGTTGGGTATTGTTATTATACCGTGGATGATTAAACCTCTTTTTGGGTTTATTACTGATGGAGTACCAATATTAGGCTATCGACGAGGACCTTACATAATTTTTTCTGGAATACTGGGGGCGTTTTCTTGGGTAGCATTGGCAACATGGGTAGATACTCCACTAACAGCGACAGTAGCGATCGCTATGAGTTCCTTGTCAGTAGCTATGAGCGATGTAATAATTGATTCCCTTGTTGTAGAAAGAGTGCAAAAAGAATCTGTCAGTAATACAGGTTCTCTCCAATCTTTATGTTGGTCTGCCTCAGCATTAGGAGGACTAATAACTGCTTATTTCAGTGGTTATTTACTAGAACATTTCAGCCCTCAAACTGTATTTTTAATTACAGCCACTTTTCCTTTGATTGTTTCTTTAGTACCCCTATTAATTGAGGAAAAAAAAGTTTCTATTAGGATTAACTTTGATAACGTAAAACAGCAAATTAAACAAGTCAAAAAAGCAGTTATAAAAAAATCAATTTTATTACCAACTGCTTTCCTAGTTATTTGGCAAGCAACCCCAAATTCTGAATCAGCTTTCTTTTTCTTTTCAACCAATGAATTAGGATTTCAAGCAGAATTTTTAGGCAGGATAAGGTTAGTAACAAGTATTGCTGCTTTATTTGGTGTTTGGCTATTTCAACGCTTTTTTAAATCTGTTCCATTTCGGAAAATTTTCGGATGGTCTACAGTTATTTCTGCTCTTTTAGGAATGACTACTTTACTGTTAGTTACTCACACTAATAGAACATTGGGGATAGATGATCATTGGTTTAGCTTAGGAGATAGTTTAGTACTAACTGTAATGGGCAAAATTGCTTTTATGCCAGTATTAGTTTTAGCTGCTAGACTTTGCCCACCAGGAGTAGAAGCAACTGTATTTGCTTTATTAATGTCAATTTATAACTTAGCTGCATTAATTTCCCATGAAGGCGGTGCTTTATTAATGCACTGGCTAAAAGTTACAGAGACAAACTTTGATAATTTGTGGTTGTTGATAGTTATCACTAACTTATCCACTTTATTGCCATTACCTTTACTAAATTGGTTGCCTACAGCTAATGCTCAAACAGATGAAGAAGAAAATCTTAATTCACAACCAATATTAGAACCTGAATCTAGTGAAATTATCTCCCGTTAAATCAGAAATTATCTTATGATATTCAAAATAATTGCACCTTTATTTGCTGAAATTTTTGGATTCATATATAGCAATTCCAATAAATGATTAATTTTGCCTCACTGTTCAATAGTATGCTTAATTTTATAGCAGTAATTTGACCTTTTTCAAGTGCAAAAATGACAGAGAATTACTCTTTTAGGCAAGGAAAATAACCAGCTATTCCTAAAAATAGCTCAAAGCTAGATAAATCAGAATACAAATTAATTAAATATAATAACTATAATATGTAATAGTTTACAGTCTTTTTATCATTTTTTTCCCTATAGATAGCAGTGAGTAATTATAATACTGATATAACCTAGATTCCACAGGACAAAATGTAGTAAAATTAAAAGTATGGAGTGCGAATGCCTATTCGCCTCTACAACAATCAATAAAAAATTATAGTTGTCAATAGAAGTCAACAATAAAGTAAGTATTTATATTTAATATTTTCTTGATCAGTTAACGTGTATAATGTGATATATTATAAATTTATTTATTATCAACATAAGAATATATAAATCACAGATGACAAATTTACAAATTCAACAACCTAAATCTTATACTAGTAAAGATTGGCAACAAGGATATAAATCTCAACCACAAGAATATAACTATTGGATTGATGATATAGAAGGTGAAATACCAGAAGATTTAAACGGTACTTTTTTCCGTAACGGACCAGGTTTATTAGACATTAATGGTCAACTTATTGCTCATCCTTTTGACGGAGATGGAATGGTTTGTGCAATTAGTTTTAAAAACCGTCGCGCCCACTTCCAAAATAGATTTGTTAGAACAGAAGGTTATGTGGCAGAAAAAGCGGCAGGAAAAATTCTCTATAGAGGTGTTTTTGGTACTCAAAAAACAGGTGGTTGGTTAGCTAATCTTTTTGATTTTAAACTTAAAAATATTGCCAATACTGGTATTATTTATTGGGGTGATAAACTTTTGGCATTGTGGGAAGGAGGGCAACCTCATCGTTTAAATCCCCAGAATTTAGAAACCATTGGCCTTAACGATTTAGATGGGCTTTTACAACCAGGTCAAGCTTTTTCTGCTCATCCCAGAATTGATAAAGGAAAGGATGGAAAAGGAGATGTTTTAGTTAATTTTTCTGTCAAACCTGGTTTATCAAGTACCATTACTATTTTTGAATTTAATAGTCAGGGAAAATTACTCAAACGTTACTCTAATTCTATTCCTGGTTTTGCCTTTTTACACGATATGGTAATTACACCAAATTACTGTATTTTTTTTCAAAATCCTGTTGCTTTTAATCCTTTTCCTTTATTACTAGGGTTACGAACTCCAGGTCAATGTTTAGAGTTTTTACCTAATAATTCAACACAAGTTATTTTAATTCCTCGTGATGGTAGTAAAGCTATAAAAATTTTGAAAACGAAACCTTGTTTTGTATTTCATCATGCTAATGCTTGGGAAAAGGACGGGGAAATTTATGTAGATTCTATTTGTTATGAATCTGTCTCACAAACTGACCTAGGTGATAATTTTCTGGAGGTGGATTTTGACTCAATGACAGAAGGTAAGTTATGGCGATTTAAGATTAATTTATCAGAGAATAATGTGGAACATAAATTGCTTGAAAGTCGTTGTTGTGAGTTTCCGACTTTAAATCCGAATAATGTAGGAAAAGCTTATCGATATTTATTTATTGGAGCAGCAGATAAGCCTAGTGGAAATGCTCCTTTACAAGCAATATTAAAAATTGATTTGCATACAGGAAAACGTCAAACTTTTAGTGTCGCACCGCGAGGTTTTGCAGGAGAACCTTTATTTGTTCCTTTTCCAAATGGGGTGAATGAGGATGATGGTTGGTTATTAATGTTGATGTATGATGCAGCAGAACATCGGTCGGATATTGTGATTTTGGATGCTCGTGATTTGAATAAAAAACCTGTGGCAAGATTACATTTAAAGCATCATATTCCTTATGGTTTACATGGTAGTTTTACCCCTAATTATTTTCAAGAGTAAGTCAGATTTTTAGGGAGTAGATAATAGGAAAGTAGTAAACATCAAAATAATTAAAAACCTAAAAATAATTAAAAACCTACTGAATAATAATTATTAAAAAGGTTATTTATTGGAGCTTACCTCACTGGAGTAAATTTTAGTATGTCTGAATTTAAAACAGACTTATATCACTTAATTTTACCTCAGTGAAGGTAATCTTGTTCGTTTCAGAAAAGACCACTTCAGATAAACAGAAACTGAAGTCAAAAGTAGTGAAGTAAAAAATGCAAAGTTTAGCAGTAATAGCTGTTGAATTACTGAATAACGTAAAAATTAATTTGATTGAACGAGAAGCTATTTTTAGAGATTCCTCAGAAGACTATTTTTTTTCAATCTATTAGTTTTTTAAAGAAGCACTCAGCGGTTAACCTTCAGATAATCTTCAGTTGAGTAACTACGATATTCAGTTATTGCCGATAAAAGTTTTATTAATTGAGCCAGAATTATGATTAAAGTTCATAGTAGTGCTTTAGTCTGATCTATCTTAAGGTTAGAGCCTTACTACAAACAAAAAAAATTTTAATCTTTCAATCTAAGGAAATTTTAACTCCGCCAAAATTAGCCTTAAATTTTCATTCATATTGGGTTCTAAAAATACCCATTTTTTTACCTGAATTTGAGTTTTTTTTAAGTAAAATACTCTTCCTTATTCAGATATCTAGACATTTACATTTGTTCCAAACAAGATAGACCTTTATTGGTAGCTTGAATTAAATCTAAAAATGACTTAAAAGACCAATATATAACTTTTAAAGTTTGCTTTGTAATATCAGTTTAAAGTAGCTAGTAGTTTTCGTTATTCTGGGAGTAATGCTAGTTTGATTCAGATTTTAGGCAAAATAGAAATACCTAACAACAATATTATTCCGTGTTTCATACATAGCATATTTCCAAGTATATGAAGTATAAATATTAACAATTAAATGTTTCCAGGGCGGGCATCTTGCCCACTGGGGTGTATCTCACCAAGGTGGAATTCGCTGTATGTTTAAATAATCTAAAAATTACTTTAAGGCTTTAACCTCTTAGATAGACTAAGTTTCTAATTTTTTTCTTTTGGCTCAAGTACATAGTCAATGTTCGCTATACAATAAATACTGTAGCGAAAATATTCAATTATTGTGATATTTTGACTCTGGATAAAAACCCATCGTGTCGTTTCCATCCCAGTATTAAAACGAGCTATTTTTCCACTTACTGAAAATTTACAATGAATATACAAAAAAATCAAGAATATAATTATCAAATAGGTAATTATTTAACAGCAAATCATCCTACTTATGTCATACGAGCGGCAGATAAAGAATTATTTAATACTTTGAAAAACGGTGAATATTGTTATGTATTAAGTTCTCCACAAACTGGTAAGTCAAGTTTAAAAGTTAATACGACCCAACTTTTACAAGCAGAAAACATTATCTGTATTGCTCTAGATATGAGTAGAGTTAACAATAAAACTTTTACTCTAGATGAGTGGTATGATCAAGTAATTTTAGCTTTAGAAAAAAGTTTTACATTTCCACGGTATTTTCCAGAATTATGGTGGGAAGAAATGGCAAATATGCCAGGGGATGAAAAATTATTTGTGTTTATAGAGGAAGTATTATTAGCTAATACTCAAGATGAAAAGATAGTCATTTTTATAGATGAAGTGAATGATGATAGTGTTTTTGACCCTGGTGGTGGGAGCTTAGGAATATTAATTAGTTATTGTCTTCAAGAAAGAGCAAATAACCCAGAATTTAAACGTTTAACATTTGCCTTATTAGGGACAACAATACCTAATAATTTAGTGGATATTTGTAGACCTATTGAACTTAGTAGCTTCAAAATAGAAGAAGTGCCTCATTTTGTAAACAGATTCCAAGGGATGGTAAAACAGCCACTAAAATTTATAGAAGAAATATTATTTTGGTCTGGTGGACAACCATTTTTGACGCAAAAACTATGTCAAATAGTTATTAATTATTTAAGAGAAAGAAATGAGGAAGAAGATGATAATAATGTAACTTTAGTAGAAGATTTAGTGGGAATTTGTGTGTTAGAAAATTGGGATGCACAAGACTATCCAGCTCATTTCAGCAAATTAGAAAATCTTTTGCTGAAAAATATACAGAAATCTACAAATCATTTAGAAATATACCAACAAATATTAAAATATGGCAGATTAAAACTACCTAGTGAAAGTAATCAGAGATTTAAAAATCATGCGATCGCTCATAGCAAATGGGAAATAAAAGAGTTATTGAGGTCAGGTATAGTCAAAATAAATCAGGGATTTTTAGAAGTATATAGTCCTATTTATGCAGAAATTTTTAATCAAGAATGGGTACAAAAACATCTACTACAAAGAACTAAGTCTGTTCCTAAAGTTACTGAGGAAAAAATTGAGTTAAATGATTCAAATGCTGAGGCAAAAACTTGGCAAGTAGAAGCAAATGTATCTAATTTTGAAATCCCAGAAAATCAAAAAAATTATAGTCATAATGAAATTAATTCAGAACAAAAATTACTAGTAAACCCATTTAAATTAAAGAATTTCAACAATCAAGTCACAAATTTTCAACTAGGAGAAAATTTCTCTGGCTTAGAAAGTCAAGATAATCAAAAAAATCAGAGTAATAATATTATTGATCCTGAACAAAAACAATTAGAAAATTTATTAGATTTAAATCAGTTTGATAGTTCAGTGACTAACTTAAATTTAGAAGAAAATATTTCTAATTTGCAACTTTTTGAAAATCACCAAATTCAAAGTAATAATTTAATTCATCCACAACAAAAAGAACTAGAAACACCTGGAGAAAAAATCACTCATCAGAAAAATAATAAGAATCAAGTAAGAGACAAAAAAGCTAAAAAATTAGCAATATCTCAGCATAAACTAAATATAGGAATAGCAGGATTAGTCGTAGTATCCCTAATAGCTATAACTGGAGCAACTTGGGCAACTAAACTTTTTCAAGAGAAACAAACTCAACTTCAAAAAGCAGAATATCAATTAGAACAATTCAAATATGAACTTAAAGAAGCACAAAAAGGTAAAGAATTAGAACATGAAGGAATTAATGCTCTAAGGCAATTTGAAACTGCAGAAATAGAAGCATTAATATCAGCAATGAAAGCAGGAATTAAACTACAAGAATTAGTTAAATATGGTCGCCCACTCCAACATTACCCAGCCACAAGTCCGATATTTGCCTTACAACAAATTATTAACAATATTCACGAAAAAAATCAAATTCCTAACATCAAAAATATTGCTATGAGTCCTAATAATCAACTATTAGCTATAGTCAGTAATGATGGTACAGCTAAAATTCTGGAATTCTCAGGTGAACCTATTTCTCAGTTGAGAGGACATCAGGGCAAAATCTCTCAAATTAAGTTTGCCCCAGAAGGTAACCTTCTTGCTACGGCAGCAGATGACGCTACAGCTAGAATTTGGGATTTTCAGGGTAAGCAACAAGTAGAACTCAAAGGCCATAAAGGTCAAATTTGGGAAATTACCTTTAGTCCTGATGGTAAATTATTAGCTACTGCTGGAGAAGACGGCACTGCTAGAATTTGGGATATCTCAGGTCAAAAAATAGCCATTCTCAAAAAACATCAAGGTCGCATCTTAGACATCACATTTAGCTCTGATGGAAAATATCTAGCTACTGCTGGATGGGATGGTACTGCCAGAATTTGGAGTCCATCAGGCAAACAATTAGCTATACTTAAGGGACATCAAGGTAGTGTAGAAAAAATTATATTTAGCCCTAATGGAAAATATCTAGCTACGACTGGATGGGATGGCACTATTAGAATTTGGAGACGTAGTTCCGGTAAGCTATTATCTAAACTTAAAGGTGGAGTTTGGAATATTAGCTTTAGTTCCGATGGTAAAAGGTTCGTTACAGCGGGAGAAGATGGAACAGCAAATATTTGGAATGTTTCTGGCCAACTATTAGGGAAACTTCCTGGACATCAAGGAACTGTGACGAGTATTAGTTTCAGTCCTGATGGTCAATGTCTAGCTACAGCAGGCAATGATGGTAGTGTAAAAGTCTGGGACAATAATGGAAATTTGTTGACATATCTTAAAGGACATCTTGGCCGGGTTTTGGAAATGAATTTTAGTTCTGATGGACAATTACTATTAACTTTGGGAGAAGATGGTACAGGTAGAGTTTGGGATCTAGAAGCTAATTACGAGGCCAAAATTCAGGGTAATTCTGAGATTTTTGGGGGGGTAAGTTTTAGTTCTAATAGTGAGAAATTAGCAACAGTTGCAGTTGATGGTGTTACCCGTATCTGGGATATTTCTGGAAATCTTTTAACTGAATTTAATGGATCTTTAGGTATGTTTGGCGATATGAGTTTTAGTCCTGATGGTAAATATCTGGCGACTGCTGGAGATAATAGCCAGGCAAGAATTTGGCAGGTTTTAGGAGGAGAGTTAATAGAGTTAGAGGGTGAGGAAGGGATGGCAAAACAGATTAGTTTTAGTTTCGATGGACAACGCTTGGCAACGGTGGGAGAAGATGGTGTGGCTCGCATCTGGAATAATTCTGGTGAGCGGTTGGTTGAGTTAAAGGGTCATAATGGGCGAGTTTTGGATGTAGATTTTAGTCCAGATGGAAAATATATTGGTACTGCTGGAGAGGATGGTGTTGGGAAAATTTGGGATAGTTCTTTTCGACTGGTTTCAGAATTAAAAATTGTTTCTAGTTGGATGGAGAGTATTGGTTTTAGCCCATCAGGAGAGTACATAGCTACGGGAGATAGTAATGGAATGGTCAAAATATGGGATTTTTGGGGCCATCAAATTGCTGATTTAAAAGCTCATATTGGTAGTGTGAAAAATGTTACTTTTAGTGCTGATGAGGAACAGGTGATAAGTATGGGAAAGGATGGAATGGTGAGAATTTGGGATATTACAGGACGACAAATAGGTCAATTTGAAAATGCTAAGGGTTTAAGTTTGGATGGTAAATATATAGCAACTTTGGCAGATAATGATTTGGAGTTATGGCAGGTGAAAGGGTTAAATGATTTATTAAAAAGTTCTTGTAATTGGCTTGAGGATTATTTTATCACTCATCCAGATGTGAGGAAAGATTTAGAAGTTTGTGAGTAATTAAAAATGTCACAAATAGTTGGCAACTAATATTTTTAAATAATCAGCTAAATTTACTTTACCATTTAAATTTTTAGCTATGAAAACATAATTTTTTTCATTTGTTAAATGAATATTTATTTTGGCTATGAAAATATAATTATTTTTACTTTTTAAATGTACAAATAGTTGATAGCTAATATTTTTAAACAATCAGCTAAATTTACTTGATTATTCAATTTTTTAGCTATGAAAATATAACTTTTTATTTCTGACTTCTTGGAAATAGTATAAGGTTATCAACCTGATTTATTAGTTGGGGTATATAGTACTAATTCTTAGGGATTTTTGCTATATATCCCTTAGGATAATTGAATATAATTTAGAAGAAAAATATGACTAATGATAGACCTCTTGTTGACCTAGAAAAAGCCTTGGAAGTTATTCAAAGTCAGGCAAACTCATTGCACGTTGTAGTGGTTGGTAAAATCAAAGGATTTCTTGATCCAGAGGTTTTGATGCGATCGCTCTTATTAGTTCAACTTCGTCATCCTCTATTAAATTCTCATATTGTCGGACCTTTAGATAACCTAATATTTAAAACTGAAGGTACAGAGAAAATACCTTTAGAGGTGATTTTTAATTCTGAACCTGAATATTGGCAAACTATTTTTGTTAATGAGTTAAACACAAAGCTGGAAAACCAAAAAGTATTGCTGAGAGCTACTCTAATTAAACCAACTGAAAAAAGTACAACTAATTATTTGATTACTAGAATTCATCATGCAATCATAGATGGTATTTCTGCTGTTCATTTATATTCAGAAATTTTGAGCTTTTGCCAAAAAATTGTATCAGAAAACCAAATTCCTGAAGTTGAGAAATTAGCACCCCCTCCGTGTTTCGAAAAAATAATTGCTGATTACAATATACAAAATAATACAGAATCATTAATATCAGAATTAGGACAGCCAATAGATACTCTTCCTTTTGAAAAATATGTACCTTATAAACAACGTACTTGTGGGTTAATTCAAAAACAATTAAATGCCAGTTTAACTCAACAACTTATTCAACATTGTAAATCAGAAAAAGTGACTGTTCAAGGAGCTATTTGTTCGGCAATGATGCTGGCATTAGCTAAAAATTTAGAGCCAGAAGATAAAGAGTTTTCTTTTAGTTGCTATCATGCTGTAGATATGAGAAAAAGACTAAATTATCCTATTGGTAATGAACAGATGGCTTTCTTAGTTTCTAGTTTATTGTGTTTTCACAAAGTTAATCAGAAAATGTCATTTTGGGGTTTGGCAAGACAAGCTACAGAGGAAATTAAAGCCAAACTAAAAACACCAGAAATTTACCATCGTGTTTTGTTTTTTTCTGAAGCTATAAACATGATATTAAAGAATCCCGAAAAAACTATTTCTTCTATATTTGTATCTAATATTGGCAAGGTGAAAATTTCATCGAAATATGGTCAATTTCAGTTAGAAGAAATTAGTTTTGGTTCATCAAATAAAATGTTTGGTAGTACTTTTAATGTTAGTGTTTCAACTTTTCAAGACCAAATAACTTTTAACTTTATATACACTCAACCTTTAGTTAGTCAGACTGTTATAGAAAAGCTAGTTAAAGATTCAATAGAATATCTAGTAACATCTTGTAATTAAATACATTAGATTTGGTGACTAATATGGTAGTAAAATCAATAGTCTCACCTTTTAAAGTAAAAAAAAGATTTGTCATAAATATTTCAGGTAGATACTTCAATGGGAGATACTGATAACTGATAACTGATAACTGTTTCGCTACAGGACATGAAAAACCCAGTTCCTACTTTAGGAAGCTAACTATAACTTAAATAACTCAGCAAGCATTCAACAACTAAATGCTTACATGACTCATCCCCAGAGGTTAAAATTATGGTCAGCTAAAAAAATGGAAAGCAAAGGGTTAATGCCCCTTTACCAAGTATCATTTTAGAACCTCTTCGGCCTTAGCCAAGGGAAAAGTTAATGATAAAACCTAATACCTATAAAAAATGCTGAATCTAAGACAACGTTTTTCATGGCCAAAAATTTTCTTGAGTTTGTTGAGTTTTTTACTAGCAATCTTTTTTTTACTGCTAATAGCAATACCTACTGCTTTAGCTAGTCTAAATGATGATAGATTTGATGGTAATATATTTGCTCTTTATGCTGGTAATGGTTCTCTTGTACCTGCTAAGGTGAAATTAAAAGATTCTTTAAAAAATTCTAGACCTGCCCTACTGGTATTTTTTCTTGATGATAGTAAAGACTGTAAGCAATTTTCGGCTGTGGTTTCTCAACTTCAAGAATTCTATGGTCGTGCAGCAGATTTTATTCCTGTTAATGTAGATGCTATGATTAATACTGTGACTGATGATTCTACAAAAGTAGCTTATTACTATCAAGGGTTTGTGCCTCAAACTGTTTTAATTAACCAACAAGGAGAAGTTGTGATCAATGAGAAAGGTCAAGTTTCTTTTGAAAAAATAGACGATGTTTTTCGAGAAGTTTTTGATTTATTACCGCGTTCTGAGTCTGCTGAACTTAAACGTCGAATTGTTAATGAAATTAATGTTGAGTTGAGAGAGTAATATCAATGGGGCGATATAGCAGAAGTAGGAACAAATAGCCATTCGCCCTCAGGGGGTGAAAAGCCCCTCAAAACTATTGTTGGATGAGGGTTGAGACTGAAATTTATATGTTAAAAACCATAATTGATAAATTGTACAAAGTGTGATCCGAATGCCCCCGAACAAAACCCCGTAGAAGATATTTGGTTACCAGCCCAAAACTTCAGCATACCACTTGATAATTTTTGCAGTTATTGTCAAGTATTTAAGTAGCTATTTAAGTTTTTTGCCATGATCAAATATTCAATTTTCTCCAACTTTTTTAGTATAAAATTTGGCAACAATTAATATACAGATTACTATAGCTATGTTTATAATACAATAAAATTAATTTATTTATAATCATTAAATAAGTATTATTGATAAGGGCTAGATTCATCTTTTTTGGCAAATTTTTGGTCATCAGACTTCTTAGTCAACTTTTTTTACCCCCCAGTTATGTTCACTTAACTTTTCTAAAAAAATTTTGAATATTTATTTTTATTTTGGGTCTTTTCTTAGTAATAATTACTGAGTTAGGCTTGTATATATTATTTAACTTAGTTGAGCTGAAACTAAGCAGTTTCTCTAATTGTTTTTTTTTTACTTATTTCCTACTATATATAAATAGATAAATAACATTAAAACTTTTGAACTGCAACTAAGGAGTTAGAAAATGTCTAATAGCTATATTTATGGTACTGGAGAAGACGATCTGCTATATGGTACCGGAGGAAACGATAAGGCGTATGGAAGCTCCGGAAATGATATTATCGAAGGTAAAGGAGGTGATGATGAACTTTATGGTAATGGTGGGAATGACACAATTAAAGGAGAAGAAGGCGATGATACAGTTTTAGGTCATCCTGGAGATGACTCAATAGAAGGAAACGCAGGTGATGATAAGCTTTATGGTGGTGATGGGGATGACCTAGTCTCAGGGGGAGAAGGAAACGATATGCAGACTGGAGGAGGAGGAAACGATACCATAGAAGGAGGAGAAGGTGATGACAAACTTTATGGAGGGCCTGATGATGACTTGATCAAGGGAGAAGACGGTCAAGATAAGCTTTATGGTAATGATGGGAATGACGCAATGGAAGGAGGTGCGGATGATGACACAGTTTTAGGTCATGCTGGAGATGACTCAATAGAAGGAAATGCAGGTGATGATAAGCTTTATGGTGGTGATGGGGATGACCTAGTCTCAGGGGGAGAAGGAAACGATATGCAGACTGGAGGAGGAGGAAACGATACCATAGAAGGAGGAGAAGGTGATGACAAACTTTATGGAGGCCCTGATGATGACTTGATCAAGGGAGAAGACGGTCAAGATAAGCTTTATGGTAATGATGGGAATGACGCAATGGAAGGAGGTGCGGATGATGACACAGTTTTAGGTCATGCTGGAGATGACTCAATAGAAGGAAATGCAGGTGATGATAAGCTTTATGGTGGTGATGGGGATGACCTAGTCTCAGGGGGAGAAGGAAACGATATGCAGACTGGAGGAGGAGGAAACGATACCATAGAAGGAGGAGAAGGTGATGACAAACTTTATGGAGGGCCTGATGATGACTTGATCAAGGGAGAAGACGGTCAAGATGAGCTTTATGGTAATGATGGGAATGACGCAATGGAAGGAGGTGCGGATGATGACACAGTTTTAGGTCATGCTGGAGATGACTCAATAGAAGGAAATGCAGGTGATGATTTACTTTCTGGTGATTCTGGGGATGACGTAGTCTCAGGCGGAGAAGGAGAGGATATACTGTACGGAGGAGCAGGAAACGATGAACTTTATGGTGGTGATGATAATGATACCATTGATGATGGTGGTGGGGATGACATACTAGAAGGAAATACGGGTAATGATATACTTCGTGGTCGTGGAGGTCAAGACGAGCTCATAGGAGGTGATGGTGATGACCTCATCATTAGTTATAGTGATGCAGGAGAACCTGAAATTGCCCAACAGACAAATGAATCTAAGGTTTATCCAGATCAACCCTTTTTTGAAGCTAATGATACTTTAACTGGAGGATCAGGGGCTGATACTTTCCTATTTAGACCGTTGATGAATGCCAAGCCTGAGATTATTGAGAAACACAATATGCACAATATGCACCAAGATATGCATAATATGAACTTGCATAAACAAATCGCTGGCGAAAATGGTTCAGTCCATGATCACTGGGTTGATAGTATTGGTGATGATATCATCCTTGACTTTAATAGAAGTGAAGGGGATAAAATTGAGATTAAGGGTCATACAGTAAAAGTAGAAAAAATTGAAGAGCTTGATGATGGAAGTGGATCTATTGTTCATTTAATTAGTGATCAAGGGGCTAATGGTGGAGCCCACCACCTAGATAAACTAGGAACAATTACTGTTTATGGTGATCTGGTTACAGAATCAGATTTAATAGCAGATATCTTTGGGGATGGTGCTGGTATGGGTTGAGAATTATGTCTATCATCAACAATTGATATAAAAATCAACTGAAAGAGGAGGTGTTGTTTAGGGTATCTAACCAACACCTTCACTAATAATCACAAATTATCTCAAATTTCAATATTCCCATTAAGCCATTAAACCTTTATCCTACAATCGTTTTGAGTTACTTGTTTCTCCGTGAATTTGGACCCATATCGGCAACCATCATTACTTTTAGGAATAGTTAAGTACCTTTGCGATCGCCTGAAGATGAGACTCTTTCTGCAGATTTTTTTGATATTTTTGTAATTTTTCTAAATATTTTTTTCTGATAAATTGAATTAGAAAAAATTCAGTTTTTGATTACCATGTTAAGTATAAGCTAGGGAAATTTCTCTGAGTAAATATTTAGCTAATTAATTTTCCTTGACTAACTTATCTAATAGACCTCTCCAAAATAAAAATTAGGGTAAAATTGTAGTGGCTAATTATATATATCCTGTTTCCAAATGAATAATGTATTGGAATATATTTATAACCATCCAAAAGAAACAAAAATAATTATTGGTATTAGAGATTAATAGCTAATAAAATCAATATAAAAACCTCAAAAGTTGAAAAAATAAAGATAGGCGATCGCCAGCCAATAAAAAAGGTTAATCAAAGCAGGAGGAGGAAGAAAAAAGTCTTTAAGCAAGACATAAGAGATAATGTTGAGCTTATATTATTTGTATCATATACCAAAATTTCGGCGACTAGGAGTAATATTTGGAGTTAGCTCATCAACAGCAAATAATATTTTTCAGGCTTTAGATAGATATTTTGAGGGAATTATTACCATCTAGTTTACTAGAGGAATTCTCGGGAAAAGAAAACAAATATTTATGGATAAAAGAGGCTTTGACAGAAATAGAATATGATGATAAACAGAAAAAGTATTATTCAGGAAAGCCAAAAATTCATAGGTTTACAAATCAAATAGTAATCACAGAAAAGGCAGAAAAATAGTATATATAATAGTAGGAGAAAGAGGTCGAAAAGGTGATATAAAGTTATTCAAAAAAACACAAAAAAGTTGGATAGAGAACAAATTTTTCAAGGAGATAAGGGCTATCAAAGTGGTCAAAAAATCAACAAGCAAAACGAAAAAAAATAAGCTATAAAATGTCAGAATAAGCAAATAAAGAGAATCAAAAAAAACACAAAAAAGAATATTTTTATAAAATATAATAAGACTGATAAAAATATTTATATCGGTACTAAAAAGATTGAGATTTAAAGATAGTAATCATGAAAAAGTAGTTTAAAATATGTGGTTTAGTCAGATTAATAAGAGGAGAATTAATATTCTTATAAATTAGAAATTTTGCAAAAAAAAATAATAAAAAACTAGATAAAAATGGTAAATAACTAATAGTAACTATCTGTAATACTATAAAGCCCGTAAAAAATGACTATCTAATGGAGCTGGCGATCGCTCCCCAAAAGATAGTTACAATAAATGCTTGATAATTTTTGGAGATGTCTATTAAAGCCACAAGATATAGTAATTTTAACCTAGTTTAGTTAATTTTTTTCTAAAGTTCCAGTTATTTGTAACTCAAAAGCTGTATATTCCCCACCCAAAGCTTCAACTATTGCCTGAGTATTAGACACCAACATTTTCGTATAACTATCTCCCTCACTCCCTGGAGCCCCAATAGAATCAGAATATAACTCCCTAGGAGCTAACCGTACCCCAGCTTCCTGAGCTACCGTAGTAATCAACTTAGGATTAATAGTAGTCTCCGCAAAAATAGCAGGTACTCCACTTTTCTTAATTTCCTTCACCAAATTTTTTACAGTCTGCGCACTAGGTTGCTCCTCCGTACTCATCCCAATCAAAGTTCCAGTCATCTCTAAACCATAAGCTTTCGCATAATACTCAAAAGCATCATGGGTAGTCACCAGTCGGCGCTGACCTTCCGGAATAGTTCCTATTTGTTCCATGATCCAAATATCAACCTGCCCTAACTCCTCAACTAATTTGGCAGCATTTTCCATAAACACCTCTTTATCTTCCGGTGACAACTCAATTAAAGCATCCCGAATACCTTTCACCATTACAATTCCATTTTCCGCATCACCCCAAACATGAGGATCTGGCACTAACTCCCCCTTACCCAAATTTTGTAAAGGCTTCACCTTTTCCCCCACCGCCAACTTTTGAGCCTTTATACCCGCAGCATTCATAAGTTTAATTAAAGTAGGTTCCAAATTATAGCCATTATAAATAATTAAATCTGCTTTCTCAAAAGCCACACTATCAGTAGGAACAGGTTCATAAATATGAGGGTCAGCCCCTGGTTTAATAATTCCCTGATGCTCAATTTCATCTCCACCTATTTTTTCTGTCATATCAGCAATGATCGTACTTGTAGAGACTACTAAGAGTTTATTCTCACTCTCAGGGGAAATATTTGAAGATGGGGCAGCACAACCACTTATCCATAATCCTAATAAAATTCCTAACATTGACCAAATTGTATTTTTCAAATCTTGAGTAGAAATATTAAGCAGGTAGGCCAAATTATTTGTGTATTTACCACTCAGATATATTTCCTGTTTCCTGTTCCGAGTGAAGCCTTTTCTCACTGCATTATTAGTTAAATTAATTTGGAACAGATATCTACTAATTTTCATGTTTAATTTTGATTTAGTTGACAATTTTTCATATTCTTTTCATAATTTATATCATATTACTTTCATATTTCTCATATTCCAGGGTCAAAATTTGAGAGGTATCTCTATGAGTGAGAAGATTTCAAAGAATCATACTTGATAATTGATAGGAGTTATAATTAATGAATGAGGACAAAATTACAATTAGTCATTTAGGAGTCCATTATCGTACCCTTGAGGCGTTGCGAAACATTACCCTAAAGATACAAGCAGGAAGGTTAACAGGTATTATTGGCCCTAATGGAGCAGGAAAAAGTACTTTATTAAAAGGAATGCTGGGATTAATTCCGGTGAGTGGAGGTTCTGTAATCTACAATAACAAATCACTTCAGAAACAGTTAGGCAGAGTTGCCTATGTTCCTCAGCGATCGCAAATTGATTGGACTTATCCTGCGACTGTCTGGGATGTGGTAATGATGGGTCGAGTCCATCAGACTGGTTGGTTTTGTCGCTTTTCTAGGATGAGTCGCCAGATAGCATTGGAGGCATTGACAAGGGTGGGGATGGATAGTTATCGCGATCGCCCCATCGGTCAACTTTCTGGTGGTCAGCAACAACGGGTTTTTTTAGCGCGGTCTTTAGCTCAGAAAGCAGATATTTTCTGTTTTGATGAGCCATTTGTTGGGGTTGATCAGAAGACTGAAAATATTATTTTTGAGATTTTTCACGAGTTAGCTAAAGCTGGAAAAGTTGTGATAGTTGTTAATCATGATTTGGGAAAATCTATTACTAATTTTGATGATTTGATTCTGTTAAATAAAGAGTTAATTGCTGTTGGCAATCGACAAATTGTATTACAAGAAGAAAATTTGTATCGTGCTTATGGGGGTAAAGTAGGTTTCTTTTCGGAGTCCTTAAAGCAAGTTGCTTGAACGTTCTAGATTTTGTTTAGTAGGAAGAGCTTCTCACTAATTTTTTTGATTATGATCATATTTTTACTTGTTATATTATTTTTTATATTTAGTTTTTAACAAGTAATTATTGAAGCAATAACATCATTAACTTGATAAATTTATCTTTAAAATATTTATTTCAATTCAACTAAAATGTAAGGGATACTTATTAAATGCTTTTCTTTATATCAGATTTAGTTCTATCAATCTTTCCTTCTAAATCTGATTCTCCAATATGATTTTTACCTGTGTTATCAAAAACTTCCAAATGAGCAGATTTTCCATAATGTAGATTATCCACATACCAAAGATATCCTGTTTCTTTCTCTTCATAAATTGTCCTACCATCATATTGATTTTTAGTTCGTTTAAATCTATGAGTATCTTTTAGTATTGTTTGAGTATCTGTAGGTGGAGAGCTGGAAGATTCATCATAGTTTAACTGACTTAATTGACAACTTTTTTCCAACCAGTTTTGTAATCCAACTTTCTGATCAATACTATCTAATTGACTTAGATTTTCTGTATCATTATTTTTCACAATAGAGATAGAATTGCATTCTCTAATCTCCTGACTTAGACATTGAAAACAAGAATCTCTAAAATTAATTAATAAGTACTTTGAGTCTAAATTAATTAATTGTCTTTGTGCCGCTTCTGCTAAAGATGTATTTGTTGCATCTTTGTAATCTTCACCATCAATATAATCAAAATTATCTTGTTCAGAATGAATTCTTTCTTTTTGCCAATCCTTGGAATTGGCTTTATTACAGATAATACTGATAATTGACGTTTTTAAGCCTTTGTCTTTAATCTGATTTAAACTAGATTTAAAATTATTGCCTTTGATTGCTTCATAATTTTTAATAGCTTCAGTCGAGTAAGTTTTTATGCTTATATTTTTTGTGCTTATATGTTGTTTTTTTAATTTATTAATATCTTCAAAAATACTTTTGATAACTTTGGCCGTCTCTTCAAACTATTTTTAGGTATAGTATTGCTCTTGTAAAGACACTTCATTAATAAACATTTCAATTTTAATCATTATTTTAAATCCCAAAAAGACGTTCAAAATCTTTATCCATTTGAAAGATCTATAACTTCTTTTGTTATGTGAAAATAATATTTATTTGTAGAAACATCAATTATTTTATCTGATATCAAAATACTAATGAAATATTGAAATAATGAAATACTCCGTGGAATTAGACTTGTTTTTGTTGATTGAATTTTCTGAATTACCTTTTTAGCTTTTTCTTTAATCTTTTTTTCTTCAACTACATTAATTAACAGACGATATAAGTTATCGCAAAAACGGCTCATATCTTTTGGATAAAGCTCATCTGGTATTTTTTTATCTTCAAATAATTTATTTATTTCTTGAGCAAAATATTTTTTATGTTTAATTTCTTGATAACCATTATCTTCAATAACCTCAGAAGTTTTTTCAAAAGCAAGTATTAATATATCTAATTATTCAGCCGTTGCTTTAATTTGCGCAGCTAAAGATTATCTTTTTTAGGAATACTCATTGCTGAATAATCATCAAGTTTATCTATGCCCAATCGAATTGTATACTAGTCACATCCAAATAGTAGGATAATATAATTTATACCTCCTCACCCCAGTTTGAGTGCTGCTATCGCAGTATAGCGACGACGCTCTTTTTCCGATCATGATTTATACAGTTTTTTCATTTATAGCTTTACTTTTTTAGGATAGGGACTTATAGAATTAATATAATTAGAATTTCAAATAATATAACAATTAGTCTATAATTACTGTGTTGATTTTTGGCTCTTATTTAATTTTCATTCCTTCATCGGGTCAATTCTAGACTTATAAAAATAGTACAAGCCCACACCATACTTAAGTTATTGTTGGGTCATTAACTATCCATTATCCATGATCAATTAATATTGTAGGGGGTTTGGAGACCAAACTCCCCACCTATATCCATCAAAAATTCCTACTACCGACTAGATCAGAAGATTTTTCAGGCTTTTCTTCAGCTGTTGTAGGAAAAACTCGCAAGTTATCTTCAGCAATAGATACTTTTACTTTAACTCCAATTTTTAATGCCACCTGTGGAGTAGTACGAGCAATTAACTCTTTTCCAGACTCAGTTTGTAAACAATAACGAAATTCACGACCCAAAAACTGGCGATCGCGAATCACTATACACCCCTCATTATCAGCTTTCAAAATCAAGTCTTCCTGACGGATCATCAACTCAAGACGATCAAACTCATCTAAACTATCAATTTCCCCACCAAACACATTATTATTTGTCAACTCAAAAGCACCCACTTCCGTTTCCCAAACCTGGTCGTGACGATGTGCAGGCAAAAAATTAGCCTGAGTCACAAACTCCGCCACAAACTTAGAAGCAGGTTCAGTATAAATATCCTTTGGTGTACCAAATTGTTCTACAGATCCAGCTCTCATAACTGCCACTCTGTCAGAAATAGCCATAGCCTCCTCCTGGTCATGAGTAACAATAATTCCCGAAGCACCTGCATTTTTAAGAATATCCCGTAATTCCTGGCGTAATCTAATCCTCACCTGTACATCCAAGTTACTCAAAGGTTCATCCAATAACACCAAAGCTGGATTTGGCGCCAAAGCACGCGCCAAAGCTACTCGTTGCTGCTGACCTCCAGACAACTCGTGGGGATAACGATTTTCTAGATCAGACAAACCTACCAACTCCAGAACATCTCTTACCTGATGATTAATTTGTGTGCTTGACTTTTTCCCAGAATTATGTAATCCGAAAGCAATATTTTTGGCTACAGTCAGATGGGGAAACAAAGCATAATCTTGAAAGACCATACCAACATTACGTTTTTCCGGTACTATCCAATCATGTTTACCAGCAACTAACCGGCCATTAATTGTCACAATACCTGACTGTGGTTCCTCAAATCCAGCAATTATTCTCAATAAAGTTGTTTTACCACAGCCTGAAGGTCCCAATAAGCCTAGTATATCTCCCTGGTATAGTGTTAAATTTACATTTTGGACAGCAGTGGTAGTACTCCGAGAAAATTTCTTGCTCACACTCTCAAGATAGAGAATTACTGATTTGGTCATTTATTTCTTAACCTCCGTCATTTCAGTTATTAGTTATCAGTACCTTTAGCTGAAGCTAAAAACTTGAAATACTGAATTGAATATTTTTTTCATTTCCTTAAAAGTAAAAACTACTGACTTAATTTTATCGTCAAAAGTCACAAGTGATCAAGTCAAAAATTAATATAAAAACTGGGTTTATAAAAAAACATTGTGGAATTACCAACTGTTATGGAATAAACCAAATTTTAAAGAAAATTTGAGAATATATATAATAGTTCTCAAAGTCATCTACAAAGCTATTTATTGTTAAATTATTATAGCCATTATTTCAAGAAAAATTCTCATTTATTTTTTTCATTTTCAGAAAAGAAAAAGCTATTGACTTGATTTTATGGTCAAAAGTCATAAATAATCAAGTCAAAACTCAATGTAAAAACTAGGTTTATGAACAAACATTGGGGGGGTTACCAACAGTTATGGGAGAAACTCAATCTTAAAGAAAATTTGAGAATATATATAATAGTTCTCAAAGTCGTCTAGAAAGTGATTTTTTGTAAAATTATTATCACCTAATTGTTCTGAAAAATTCTTATTAAGTTTATGTAAACCTTTTTAATATATACAATTAAAATGTTAGGTCAAATGAAAAAATTTAACCGTCTCAACTGGAATGCTTCGACAATATTTGTTGTAGCGATCGCCTGCCTCATTTCAGCCCCTGTAGTATTTGTCCTGAGCAGTATTTTCTCTGATACAGGAGAAATTTGGAGTCACTTAGCCTCTACAGTTTTACCCCGTTATCTCCTGAACTCCTTTATATTAATGCTAGGAGTAGGTTGTGGAGTTTCAATCATCGGAGTAGGAGCAGCATGGTTAATCACAATGTGTCGTTTTCCAGGGAGCCGTATATTTGAATGGGCAATGTTATTACCTTTAGCAACTCCCGCCTATATTCTCGCCTACACCTATACAGAATTGCTAGAATTTTATGGCCCTGTACAAATGTGGTTGCGAGAAATATTTGGTTGGACTAGTATCAGTGATTATTGGTTCCCACAAATTCGTTCTCTGGGCGGAGCGATCGCCCTGTTAACCCTAACTTTATATCCCTACGTTTATCTACTAACGCGAGTCGCCTTTTTAGAACAGTCAACCTGTACTTTAGAAGCTAGTCGTTCTCTAGGAGCAAACCCATGGCGTAGTTTCTTCACAATAGCTTTACCTCTGGCTCGACCAGCAATAATGGCAGGTTTAGCCCTAGCACTAATGGAAACCCTCAATGATTTCGGTACGGTGCAGTATTTTGGAGTTGATACATTTACGACTGGCATATATCGTACTTGGTTTGGCATGGGTGAAAGAGTAGCAGCAGCACAATTAGCAGCAATGTTACTATTATTTATTTTATGGCTAATTTTGCTCGAACTGTGGTCGCGTCGGCAAGCAAAATATTATCAAACTAGCAGTCAACAACAAAACTTACAACAATTTCCCTTAGATAGAATACGAGGAATAGCAACATCTTTTGCTTGTTTATTGCCAGTTTTTTTGGGTTTTCTCTTGCCAGCAGGATTATTATTAGAAATGACTATAACTGAAAGTGGAGCCAGCTTTCGGGGTCGGTTTTGGGACTATGCTTCCCATAGCTTGACCTTAGCAGGAATTACCGCTATTTTAGGAGTGGCGATCGCTGTGATCATGGCTTATGGAGTACGTCTAAATCAAAATTTGGGAATGCGTATATCAACTCGTATTGCAGCCATAGGTTATGCTGTACCTGGTTCTGTTATTGCCGTAGGAATTTTGATTCCTATTGGTACAGTTGATAATGCTATTGATAGTTTTATGCGTTCCATGTTTGGCATCTCGACTGGTTTATTATTGAGTGGCACCATTACAGCATTAGTTTTTGCTTATTTAGTCAGATTTATGGCAGTAGCATTTGGTGCTGTTGAATCAAGTTTAGTGAAAATTAAACCAAGTTTAGATGATGCTTCCCGGAGTTTAGGTTATGGTTCTACAAAGACTTTAATTAAAGTTCATGTACCCATGATGTGGGGTGGGTTATTAACAGGAGCAATGTTAACATTTGTAGATGTCATGAAAGAGTTACCGGCAACAATGGTAATTCGTCCGTTTAATTTTGATACCTTAGCAGTAAGAGTTTATAACTTGGCTGCTGATGAAAGACTTACTGAAGCAGCCGGTCCGGCTTTAGCAATTGTATTGGTCGGAATAATACCGGTAATTATATTAAGCTTAAAAATTGCCAAGTCTCGTCAATATCAAGATTATTAGAGAAGCTCTCAGCCCTAATTAATTAGAAAGAATTAACATGTTAACTGATCATTAGCATTCATTTATCTGTTAAGTTTTAGCAGGTTTCGGATAATATTTTCAGCATTGAAAGCAAATCATTTTTTAGAAGAACTTTGTGCTCTCAAATTAGCTACAATTCTTTATAAGAGTATTATAAAATTATCAGTTTCATCAGCTTTGTTGCACAAAGCCTCTATTGTTATAAAAGCATCAAAACTTGATGATACTAATTTTAATAATTCCCCATTTTTTATTCCTGCCCAACCTTGTTCGGGAACTGTTATTACTTGATGATTTATGATTTCTTTTTTGAGTTTTTTAGGTAAGCACTCATCCAGCAATATTTTAATAAGTTTGTTTCAATAATGTTTCTTGAGCTAACTTTAATAGAGAAATTGCTTGTTCTTGAGTAACCGTAGGAAAATCATCAATAAAGTCTGCTATGGTTTCCCCTGCACTTAAATAATCAATAAGAGTTTTGAAGATAGCGCGAGTATTTTTAAAGACTGGTGTTCCTGATAATATTTCTGGAGATATTTCGATTAAATTATTGCTGATAGTTTTTGCTCTTTTATATTTTGATTTTTGTAATCTTTAATTTAAAGGATAATTGATAATTAGAGATACTTTTCATTATCAATTATCCATTATCCATTATCAACTAATTATTCTATTCCTTCTATCCGATCCTCCACTTGCTGATACAACTCCCGCAACCGATCCAAATTACTCTCACCTGTCTCCCAATAACCGCGACCATTCACCTCCAACAATGTAGCTACGATCTTCCGGAACGAATGGGGATTCAAATTCAACAACCGCTGCTGCATCTGCTTATCCTGAATAAACGTCTCATTGACATCCTCATAAACCCAATTATCAACCGCGCCTGCAGTCGCACTCCATCCCATAGTATTCACCAGACGCTTAGACAACTCCCGCACACCTTCATAACCATGAGACAACATCCCCTCATACCATTTTGGATTCAACATTTTTGTTCGCGCATCCAAACGCACCGTCTCAGACAAAGACCGTACCTGAGCATTCGCAGTCGTCGTATCCGCAATATAAGAAGCTGGTTGTTTACCATCACCCCTGAGAGTTGCCACAACTTTTGTCGGATCCGAATCAAAATAATGACTCACATCGGTCAAACTTATCTCAGACGAATCTAAATTCTGAAAAGTCGCATCAGCAGTTTTCAATGCCGACTCAAAAACTTTCCGGTTATCCTCCATCATTCCTGGGTTATCAGAATTAAAAGCAAAAGACTTGCGCTTCAAATACATTTCCTGTAATTCCGACTCATCTTCCCAAGTACTATTCTCCACCGCCAAATTTACATTTGCAGCATAAGAACCGGAAGCATTAGAAAATACCCGTGTTGCAGCTTGACGTAAATTCACTCCCAAATCTTCAGCTTGCTTGAGAGCATGCTTGCGAACAAAATTCATCTCTTCCGGTTCATGTGCTTCTGCTGCCATTTTCACAGCCTTATCCAAAAGATTCATTTGATTAATAAATAAATCTCGGAATACACCAGAACAATTAATCACCACGTCAACCCGGGGCCGACCCAACTCTTCAAGGGGAATTAACTCCAGCTTATTCACCCTACCCAAAGCATCAGGTACAGGTTTAACCCCTACCATCCACATCACCTGAGCAAGAGATTCACCATAAGTCTTGATATTATCAGTTCCCCACAAAACAACAGCGATAGTTTCTGGATACTGCCCACCATTCTCCTGCATCTGTCGTGCCAATAAACGATCAACTACAGTTTTTGCCGACTTAACCGCAGCAGCAGTAGGAATAGACTGGGGGTCGAGAGCGTGCATATTCTTACCAGTAGGCAAAACATCAGGGTTCCGAATGGGGTCGCCACCGGGTCCTGGTAAAATATATTCCCCTTCAAACGCTCGTAACAGAGAACCCAACTCATTATCAGCACAAACCTGTTCTAGGCAAAACTCTAAATATTCAAACAGAGGCTTGATAGCTTCTTCATCAACATCAGGAAAACCTGCTGCTTCCAGAGCTTCTATCCAAGGTGCTTTTTTCCTCATATTAAAGAAATTGAGTTTACCCACCATCGAAACTCGACCCTCAGCATCAGTTTGTTGGTGCACTAATGCCGCTACAGCAGCACGAGTCCCTTCCGTAATATTCTGAAGTAACTCCACATCTGCCAAAATACCTTTATTATTATTTTGGTAAAGTTCCTCAATATCCCGGTTGAGGCTATTAGCAATTATTCGAGGTAAACCAGTTATCCCTTCCTCTTCCCGGTCTAAACTAGCAATATTTACCAAAGTAGCGATCGCTTCCTCAGCAGTAGGAGGTTTACCAATAACGTGCAAACCACAAGGCAACAACCGGGACTCAATTTCCATCAACCTGCGATAAACATCCCCAACAACTTGATCCCGTTCCTCAGCGGTCAACTCCTGAGCATCTTTTTCCGGCAGAGTTACATCCTGGTCTAAATTCACTATCCGGCATTTATCCATAATAGTGTTAACAATAGGAACACCTCGCCCGCTATCCTTCAAAGTTTGATAGGAAGCTATTAACTCATTCAACTCCTGCAAACCTTTATATAAACCAGCATTTTCTGCAGGGGGAGTTAAGTAAGAAATAGTCTCAGCATAACTCCGGCGTTTAGCAATAGTTGCCTCACTAGGATTATTTGCAGCATAATAATAGATGTTGGGAATATTGCCTATGAGATTATCCGGGTAACAATGTCCAGACATACCAATTTGCTTGCCAGGCATAAATTCTAAAGAACCGTGAGTACCGAAATGTAGGACTGCATCTGCTTTCCAAATTTGTTCTAAATAGGTATAGTAAGCAGCAAAACCATGATGGGGACTTGCAGAATGGGAGAATAACAACCGCATGGGGTCCCCTTCATAACCAAATGTTGGTTGGACGCCGATGAAAACATTTCCGAAACTCTTACCGTAAATAAGTAAATTTTCGCCATCGCTATTCAGGTTTCCTGGAGGTAGTCCCCAATTTTCATGCAACCTTTCCGAGTATGGTGTCAGACGTTCATATTCTAGAACTGACATTCGGTAAGCAATATTGAGCTCCGGACTTTGATATTGGGCAGTAGCATCTTGGATGACTTGCTTCATTAATTCTTCTGCAGAGTCTGGCAAGTCTTGAATATCGTAACCATTGCCTTTGAGTGCTTTCACAACTTCATAGATAGAGCCAAATACATCTAAATATGCAGCACTACCCACATTCCCTTTATCTGGAGGGAAACTGAAAATAGTAATAGCAATTTTTTTATTCAGTTTGGGTTTACGTCTAAGACTTGCCCATTTAAGAGCGCGTTGAGCTACAGCTTCGATACGGTCTTGGAGAGCGATCGCTTTTCCCGTTGCTCCGTCTCGCCCAGACATAATGATAGGTTCGATCGCCCCATCAAGTTCAGGAATAGCTATTTGCAAAGCAACTTGTATGGGGTGGAGACCAAGGTCACTTTCTTGCCATTCTTCAGTAGTTTGGAAAACCAGAGGTAATGCTACCATGTAGGGTCGGTTCAACCTTTTTAAAGATTCTACCGCTTTTGGATGGTCTTGTCTAGCAGGTCCACCTACCAATGCAAAACCAGTTAAAGAAATAACCGTATCTACTAATGGTGTAGGTTCAACTCCTTTAGTTACCACTTCCCAAAAGTAGGCATCGACCGGTTTAGAAAAATCTAATCCTCCGGCAAATACAGGCAGAACTCGCGCTCCCATTGCTTCCAACTCTTGCAACATGGCAACATAATGAGCATCATCTCCTGTCACTAGGTGGGTTCGCTGCAAGACAAGACCAACACAGGGGGCCAGGGGATCTTTCAAATTTTCGGAAATGTCTTTACGGTTGTTGTACCAGTTGAGATATTCTTTGACATCCTCAAACATTTTGGGCGCCAGGGGATGCCAGATACCCATGTCTGGATAAACAACAGGATCGACATATTGTAGAGAACTTTTTTTCTGGTCTTTGAAAACGTATTTGTCTGCCAACATGAGCAGGAAATTTTCCAGGTTTTCCGAGGAACCTCCTAACCAATACTGGAAACTCAGCATAAAGTTTCTAGCATCTTGGGCTTTGTCAAGAGGCATATACTTCAAAACTTTTGGCAGAGTTTGTAGTAATTTCAACATTCCGTCTTGAAAAGAAGAACCAGATTTTTCTTTCCGCTTCCGCATAAATTGAGCAATGGCGCTTTTGCTCTGGCCTAGTTGGGCCATTGAGAATGTTCCCATTTTATTCAGGCGCATCACTTGTGGCATGGAAGGGAAAACCACAGCAGCGTCAAGTTTGTCGCGATGGGGTGTGACGGCTTCTACGACTTTTTCTGCTAGGTCTTCAATGAAAATTAGGGAAGCTATAAAGATGTTAGCTTCGGAAACTTCTCGCCTAAAGTTTTCATAGTTTTTTGGGTCCCGGAGTTCTTCAATTAGATAGCCACTTATTTCTATGGCCAGATTAGGATTTTTTTCATTTATAGAACGCACTGCTGCTGAGAGGGAGCTTTGATATTGAGCTTCTAAAACTATATATACGACTTTTAAGAGCGATCGCCCTTTTAAGTCTGCTGGGACAATGTGGCGAACAGTAGGCTTTACGGATGTGAACATTAAGTGTTGCTCCTTGAGGGTAATAATAAATAAGTATTACTATCAAATATCAAAAAATTTTAAACAAAGGTAGGGTAAAGTCTTAGTTTGACACAATTCGATAAGAACTTTTAAATTTTTCGTTACATCTATTGACTAAAAGCAATTTATATAAGATTATGTATATCTTTTAAACTTAATATTTTGTGATGAATTAAGTAGATGATAAATTTTTCTGATAAATGGAAAAGTTAATATTGTTTTATGGAAGTCAAGCCTCTTCTTATTGCCCCCCGGAGAAAGTCAACTCTCTACTTACCCTTTTGTTATAAATATCTTTAGTTCATCGGAGACAAAAAGTGTATTGAATAATAATTTTTTTGAGGACTTAAAATAGTTTTGCCTAGCTACTATAGTTTTTCTCTCTACTCCCCTTTTAACTCGCGGTTAGATTTCCGGTAAGGTTTTCAGAAGTTCCTGAGCAGAAATAGCCTGTATAGACCAGGCTAATTTCCAGACTATAACTGGAGAATATTTGTAATACTAAGGGTAAAAAAAAGAATGCTTTTCTCGGGTAAAGCTTCAATTATTAACAGACTATTTCTAAACAAAACCTTAAGCTTTTGTAGGAAGGCTTAGGTAGACTATAGATAGGAAAAGTCGTATATTTTAAAGAGAAAGTACTTTTAACTCCTAGACTTACTCTACCAATCAAAGTTATTAAAGTACTCAAGGTATAGTAGATACTAATCATTATCTAACCTATCATTATCTTGAACATAAAGTTGTCTTGAATATGTTTAATTAGATCTAGGTATAACAATACAAATATTCCTATTTATAACCCTCTGATAAATGTCTAATAAATCAAAGAAGATATTTAAGAACTAGAACCTAAGGAGTGACTAAGAAAGGCTAAAAAAAAATTGTAAAGTTTCTTCTAGATTCTGAAAATATGGTATTATAATAGGACTAACTTATGGTTTACAATAATCATAAAAATAAATAATTATATTTGTAATAAAAACTCTTACCTAACTTAAGAACAAGCATTTTATTTTCAGTAAATTTGACCTTGATTTTGCTGAGACTAATACTAGTAAAGGTAAAATAATTGTCGAAGCTACCACGGTATTAGAATCAGAAAAAGTGCTGATGATACAAAGCATCATACAAAACATCATAAAAATTAAGAATTTATCTTTAATATTAAGGGGAAAGTAAACAACTGAAATTACATTAGTAATACAAGTAATAGATTTTATATCTATTAATTAATTTCCCGAAAATCTGTGATCCTATTAAATCACATAAAATATCAGAATATTGGCTCAAAAAGTTATGAGTAAAGTAGGAAAAATATTAAATTTTACTGTTAATCTATTGAGGCTAAATATTAACAGAGACTAGATAAGCTAACAGAAATATTGCTAACATTTCATATATCACATCCCAGTTAGCTAAATATACTAGTCCGAAAAAAAATCAGGGGTAGAAATAGTTTTATGCTTTCATTATGGTGAGAGTTAGGTATTGCTATGACATTTTGGGAAGTTTTTATAAATAATTTAGGTATAAAATTCCATTATTTCCAATAAATAATATTCATACTATAAGTCAGAATTAATATTCTAATTATAACTGCTGGCTGTTGACTAAACCTATGACTATCTAATGTAAAATTTTAAAATTATGATTGAGTATTTTTTTCTGTCTTAATCATTGTTTCTCAAAGCCAATTTTTTCCTGAATAATATAGTAAGGTCTTTGCCGAACTTCATCATAAATTCTACCTATATATTCTCCAATAATTCCTAAAGAAAGTAGTTGAATTCCTCCCATAAAAAATGTAGTAGTTAAACCATAAGCCCAGGAGAGAAATTCTTTTCCTAAAATAAATTTAACGTAAAGACCAATTAAGCCAATAATAAAAGATAAAATTGCTGAGACTAAACCTAAAATAGTTGCCATTTTTAGAGGAATTGTAGAAAAAGAAAATATGCCATCAAAAGCAAGTTTAAATAATTTAGAAACTGACATTTTTGGCTCACCCCTATATCGTGGTCCTCTTTCTACATAAACTCCTATTTGTTTAAATCCAGCATAAGCTCTTAAACCACTTAAATATTTATTGCGTTCTGGCATTTGCCGTAAGGTTAGAATCACTTTTCTATCCATTAATGAAAAGATTCCTGCATCCATGGGAGTTACAATTCCTGACAACTTTCTTTGGATGTAATAAAAGCTTTTAAATGCTAATCGTTTTAACCATTTTTCTTTGCGATTTTTTCTAATGGCATATACTACATCATATCCCTGTTGCCAAAGCCTCAAAAAACTGATAATTGCTTCTGGAGAATCTTGTAAATCTCCATCCATAAGAATAACTGCTTTACCATTAGCATGATCTATTCCAGCAGATAAAGCACATTGATGACCGAAGTTTCTGGAAAAGCTAATAATTTTGACTTTTTGATTTTTATGGTTTATTTCTTTTAGTAATTCTAAAGAATTATCTACACTTCCATCATTGATGAAAATTACTTCACTGCTGCTATCAAGTTTGTCTAAAATATCTGATAATCTGCGCCACAGCTCAGGGATAATTTCTGATTCATTAAAAATGGGAATAACTACAGAATAATCAATATATTTCATCGTATTTACTAACTATTTTAACAATAATACAAATTTTTTTTATGATTGTCAACCTAAGCATAATTAATATAATTTATAATCAAGGAATAAAGATTATATAGAGTAAAATTACTTTTCATATTAATTATTAATAATCAGTCTATTTATTCTGATAAAAACCTATTTTTTGTATTTGGTATTTCTTCCTTGAAAGCAAGCATCATAATTTTAGGTACAATATTATAAATGTCATTATTTCTAGTTTCCTGTATTTTATAATTTTCAGAATAAATAAATTACGTTCCAGGCAGTTTATCAGAAAAAAATTTAGTTATTTTGAAAAGTTTATTAACTGTTAATACGACTTTCAATACCCCTATAAATTACAGAATAGAGTGGTTAATAAAATGCCTTAACTTAGAAGTAAAAGTTATAAAATTGCGGTTTTTAAATTACTGAATTTAGTTGATAAATGAAGTATCTAAGGTTACCTTGCTTGATTTATAAATAATCTATTGTTAAAAATGATGCTTGATTAGGTTATGAACCAGATGTAATTGTTGTCAGCCGAAATTACTTTTAAAATTAACTAGGATGGGAAAAAAATATACTTTTTTTTAAATTACTGAATGTGGTTAATAAAATGCCTTAACTTATTAGTTAATCAATCAACAATCTAAGATTATTTTGCTTTATCTACTAAATAATCTATTATTAAAAATGATAGTTGATTAGGCTATAAAGCAGATGTAATTGTTGTCAGTCGAAATTACTTTGAAAATGAACCAGGTGGGGAAAAATAATATACTTTAATAAATGGTTAGTCAATTAAGTTAGTAATTGAAATTATAAGTAGTAATTGGAGGAATAATTATGCCTTTAAATTAGATGCTTATCAAACTATAGGTATTGAATAATATTGGATTTGTAGATAATTTTGGATTAGATATAAGAGAATTTATCGGTTATGCCAAAACCCTAATTTTTAAAGTTAATATCTTGAAAATAGAAATTATAAATCTAATCAATTTCAGGAAAACTACTTATTTAATCTTTTAATTTTCCTAAATCATAATTGATTACAGCACAATTTTTATATAATAAAAACACTAATTTATAATAAAAATTGTCTTTAAATTTTCATGCTTTTATGGCAGTTATAATTCAGTATTCAGGAGACTATAGTTAGACAAAAATTAGCCTATAAAAAAAATTACAATTTCATGGAATTGAGAAAATCAAGTTACTAAAAAAAAAGATTTTTAGCCGAGATTGTCTCAAACATAACTGTTAGAAGCTATTGGTCATAAAAAATAAAATTTACACTAGACTTAAGGAGACAAATACCAATTAATAAAACTGACCAAAAAATTAAATATAAAATTTGTATTTCTTGGCGCTTTAGCTACTCTATAAAGTAGAGATTATTTGGTGAAAAAAATAAAGTACAGCAGGAATTGACAATACCATTTATCAACAACTTTCTATCCTGAGATATGAAGTAGGGGAAGGACATACAAAGGTAAGTTATTAATAATTGATACTATAAGGCCTGAGTATGGGAGGTCTGGGAGAAAAATCTATTTTTATTAATGCCGCTTGTGTATCTTCGAGCTCCTGTACTCCCCAGGCTCCCTTTACTTTTCCTTACTCCTATAACTAATTATCACGATCGCGCATCTGCTTCAACAACTCCACTACATCTTTATGACCTTCTGAACCTACCCAGAGGAAAGGTGTCCATTTGTTGTGATTTTTTGCCCTAATATTTGCTTCCCTTTCTAGTAAAGTTTGCACTATACCAACATGACCACTACTAGCAGCAGTCATCAAAGCAGTCATACCAAAATTAGTAGCAGCATTAATATCAGCACCGACATCTAACAATAGTTGCAAAATTTCCTGGTTGTCACCAGCAGCAGCACCCATAAAAGGAACCCAACCATCAATGTCATTGCCATTGACATCTGAACCAGTAACTAATAATTTTTTCACGATCTCTACATGGCCAGTTTCAGCAGCAACAATTCAAGCAGTTGAACCCTCTGAGTCTTGAGCGTTGACATCCACACCCCCACTTAGCAAAGTTTCAACTTGAGCAACATCTCCAACTTTAATGGCATCTATTAATTCTGTCACTTAATTTTCTCCTATAATTTAGTTAGTATATTAGTTCATAATACCGTTTTACTAAAAGTTAGCTCCTCCTTATTCCTTTAAGGGGAAAGTCAAAAGTTGCAATAACATTTTAGGTGGTGGTGCAAAGTGAATTAGTATAAATTAAAAAAGTTTACCTCATGCCTTCCATCATGGAAAAAGTTGATATTGTCATCCTCTCAAATGGTCCGGGAGAATTAGTTACCTGGGTAAGACCTGTTGTACAAGAGTTGCGACAACAGGCGAATATTGATATGAGAATTTCTCTTGTTCTCTCCCCTTGTCCTCATGCTACGGGAAAAGAAGTAGCGATCGCTCGTTCTTATCCAGAAGTAGACCGGGTACAACCACCTGAATTTTTTTGGCGGTTTTTGCTCTGGGGTAAGACGGCAGAAAATTGGCATTGGTATCCTCAAGGAGTAGTTTTATTTCTGGGAGGTGACCAGTTTTTTACTGTTGTGGTGGGAAAACGTTTGGGTTATCGCACTGTTATCTATGCTGAGTGGGATGCTAGATGGTGGCGTTGGGTAGATAAATTTGGCGGGATGAAACCAGAAGTTTTTGCTCAGGTTCCTCCCAAATATGCTGATAAATTTACTGTTGTGGGAGATTTGATGAATGAGGTCAGAAGTAGCAATAAACTCAGAGCTCAGGACTCAGAATTCAGGACTCAGAATTCAGAATTAGTAATAAATTCAGAACTCAGAACCCAGAACTCAGAATTCAGAATTAGTAATGAACTTGCATCTGAAAACTTAGAAGTGAGAAGTAATTTTTCTAACCCTTCAAAAGGGGAGAGTAGTGTGGAGTTAATTGGGTTATTGCCTGGGTCGAAACCTACTAAGTTGTCTTTAGGTGTACCTTTAACTTTAGCGATCGCTCAACATCTCCATAAAATTCGTCCGCAAACTAAATTTATAATTCCGGTAGCTCCCACCCTTGACTTAAATACTTTAGCTAATTTTGCTGACCCGGAAAAAAATCCAGCAATTGAAAAAATGGGGGGTGTGGGAGCAAAATTATTAACGCCTTCTTTGAATAGGAAGAAAACAGATAGTAGAAAACAGGGAGCATATTTTGAAATTCAAAATTCTCATCTGGTGACAACTGGAGGTTTAAAAATAGAATTAATCACCCGGAACCCTGCTTATGACCTACTTTCTAAATGTCGTCTTTGTCTGACTACTGTCGGTGCGAATACTGCTGAGTTAGGTTCCCTGGCAATACCGATGATAGTTTTGTTACCCACTCAAGAATTAGATGTTATGAGAGCGTGGGATGGTTTACCTGGGTTACTTGCAAATTTGCCAGTGGTTGGCGCTGCTTTTGCTACCGGAATTAATTGGTTAGTGCTCCGTAAGGGACAACTGTTTGCTTGGCCAAATATTTGGGCAAAACAGGAAATTGTGCCTGAGTTAGTAGGGAAATTAAAACCCGAAGTTGTGGCAGAGTTGGTTTTAGAGTTTCTGACTCATCCAGAGAAGTTGGCAGAAATGCGCGATCGCCTCTGTAATGTGAGGGGTAAACCAGGGGCAGCACAAAAGTTAGCAGAAATTGTATTATCGTTGAGCTATGGTAGTCAAATATAATAAGATGCGACATTGGTGATCACAAATTACTATTTGCCTACCCTAATACAGTTGCCTGAAAGTCTTGATCCCAGTAGTCATTCAAAACACCAGACTCAAAAATTCCGAAATTTTCTAATTCGTTAGCACTGCCAAATATGACTATGAAAGCGCGGTTGCGTACTATTGATGCCACCACTGCCGGATAGTCAACCTCACGATATTCGTCATTATTCAAGTACTCCGCTATGATAGTGACTGCGCCAGAGAGCTTGGTATCTGGGCTTGTGGAGAAACCACGAAGGCTACCCCGAATACCGTGCTTTCGGGTGAAGTAACGACTTCATGGATTAGCTAGCCTGATCAACTAGCTGAATGTGTAGCCTGGTTGAAGCCCTAAGCCTGCCCTGCTCAAAGGTAACAAACCTTCTAATTTCGCTGGATGACTGTAAATTTAATTAAATATACAACATATTCATAAAACTGATATAAAACATTATCAGGACTTACGGACGGGCATTTCCTGAGGGTGAGGGCGAATACCAGAAGGCCCCTATATAGGTGGGAACTAGATAAATTTGCGTAAGTTCTGGTCATGAACTATAACATTTTTCAAATTTATTCGATAAGGCTCGACGGGAAATTTTTTTCCTAATTATTCAGAAGGAAAATGTAACCAGAATTGACTTAATAAGTATATTAACTTTTTGGAATTAGACACTAGCATATAGTATAATGATATATATAAATCTATATGTAAAGATAAAAATAAGTGATCAATGGCATTAACAATAGACAAATTATTCGACGAACAATTCTATCTCGAAACTCACCCAGGAGTAGCTGAAGCAGTTGCCAATAATATTATCAGTGATGGTTTTTTCCACTTTACTAGATTCGGTCAATTTGAAGATCGTGACCCCAGTAGGATTTTTAATACTAACTTTTATCTCACTACTAATCCCGGAGTTGCAACTGCTGTAGAACAAAATATTCTCACCCCTACAGAACACTTTATCAACTTTGGTCAGTTTGAACAACGAGATCCTAGTGCTTTGCTGAACACCAGTTTTTATCTGGAGCGTTATCCAGATTTAGCTGAAGTAGTTGTAAATACCCCACTCACAGCCACAGAACACTTTCTCAATTTTGGTCAATTTGAAGGTCGGTTGCCACGCCTGTTATTTAGCGATATTTATGTATTTGGTGATAGTTTATCTGATACAGGGAATCTTTTGGCTGCTGCTGAGAATTTTTTGGGTGCTACCGATGAGTTTGTGTTGGAATTTTTTGCTCCCTATTTTGAGGGGCGTTTAAGTAACGGTCCCGTATGGGTAGAAACTCTCGCACCTCAGTTAGAATTAACATCTGATCCTAACCTCAATTTTGCAGTCAGTGGAGCTACCACAGGAATTAGCAATAATGGCAACAACAGGTTACCAGAGGGTACACCTCCTATTTTTATAGGTTTACAAACGCAAATTGATGACTTTATTGCAGACACTCCTACCACTGATCCAGATGCTTTATATGTAGTATGGGCAGGAGCTAATGATTATTTAGGCGCTGGAAATTTGGATGCCCAGTCAACTGTAGATAATTTGTTAGATGCAGTAAATAGCCTTGCCGATACTGGAGCCAAAAATTTTGTTTTACCAAATCTACCAAACCTAGGAGTGATTCCAGTTGGACAGGCTCTTCCTCCTGAACGACAACAGGGATTAACTTTATTAACTGAAAGTCATAATAATACCCTAGCAACAGCTTCCCAAATATTAGAACAAAACCCAAATATTAATATTGTTAATCTTGATATTAAAACTTTATTTGATAATATAATTGCTAATCCTGATGATTTTACTTTGACAAATGTTACAGATAATTTCTTGACTTCTGGTTTGGATGACCCTAGTGGCTTTTTATTCTTTGATGATATACATCCTACTACTAATGTTCATAGTTTTATAGCAGAGAATACGATGAAATCAATTACACAAATTCCAGAACTGCTCAGTATTGTAGAAACTTCTCTGTGAGGAAAACAGAAATTACGCGGAAAAACCCGAAAACCAGGTTTTTTTAGATGTCTATTAGGCATCTAAATAAGTTTCTTATAAAGTGAAAAAATTACCGGGATTATAGGGATTAATAATAGTTAAAAATTAAGTTCTTTTTTCTCTATCAAAAATAATAGTATTTAGACAACTAATTAAGATATTTTGACTATCTTTGTAACTAATTTATTTTGAATACAAAATCAATTTTATAGCTAATAAACTTGATTTATTCTGATAAAAAAAATTCTAAAATTTAAGTTTTTTATAACACAAATAGTAGAGCATATAGTTGAGTCTCAAATATTTAGAGATGAAACATACTTGTTACCTATTTAGTAGTCTACTTATTTAGAGCGATCGCTCTATTCTAGATAAATTTACTCTAGTTATTGCATAGTAGTTTACCACTGCCCATCACTCTATAAAATTACTCATATTTGACTAGAGAAAAGCTCCTATATATTCTGGAGCGATCGCTTCCAATATTTCCCTGAGAACTAGAGCAGCTATAGTTGATGTCAAAGCCTTAAAATACTGAATTTTATTTTTTTCATCCCCCTTAAAAGGGAAGCTTAAAAACTTTTTTTTGTTTTTGGCATATACTTGCTTGGTGAGAATAATAAAGTTAATTCTAGGTAGTATAACTTTAACTTTAGATAGAAATTTTGAGATTTATCGAAAAAATATAAATAAAACTCTAGATTTGATTATTCCTGTTAATTTATAATGGAATTATTTCCATATCATAGACATACTAAAATGAAAAAAATCTCCATTATTCATCAATCAAAGCATTTCCTAATACTTATTTTATAGACACTTTTTCCGAGAATTATATAGAAAAATAGAGAAAAAAAAAGACTCTTTAACTATCAATTATTCATTATCAATCATCCATTATTAGCTAGCCAGTTTTCTAAGTCTGCTATTATTGCTAAATCAAAAATTTCATCACCTAAAATATCTAACTTTTCCAAAGATAATTGCTCTATCTGAGTCTGAACTTCTGGAGGCACTTCCCCAAACTTCCGGCGAATTTGACGTTTAACTAATATTCTCATTCCTTCCTCTCTTCCAATTCCAATGCCTTCCTCCCGTCCAATTCCAATACCTTCCTCTCTTCCAATTCCAATACCTTCCTCCCGCCCAATTTCTATTCCTTCCTTTCTGGCTAAACTAATTTGTCCTTTCTTATCTCTAATCAACTTTTCTTGTTGCTCTAATTCCTCTAATTCTTCATTACTTAAGTTAGCCATATTTGCTATATTTAATGCTGACTCTATTTCTGATACCTCTTCTAAAGAGGAAGGTATTACTTCTAAATTTGGAGCCGAGCTAATAAAATATATCCACTTATCACTGAGGGTTTCTAATACTGACAATTCTTTCTTGAATTTGGGTAATTCTACAAACATTAAAGTTAATTCATCTTGGTAATTAAACAACTCTGTCTCTTCTTTAAATCGGAATTTAGTAATCATTTTATCTGTGTTTTCAAATAAAACAAAATCGGCGATTGTTAAAGCTACAAAAGGTGTCAACATCATATAACCTTGCCCTACCTCTAATTGATTTCCATAAGCTTTAGCTAGATTATAAATTACTCGTTTTTCAAAATCTTCTACGTTTAATACTTGCATTTCAATAATCACAGTAGAACCATTATCTAAAACTGCTTTTACATCTAAATAAGTCTCTTTAATAGTGTTCGTAACTCCAGGATTATAAGGATTAATTATTTCTAGAGATTGAATAATATTCTGATTATTATAAACTATAGCATTAAGAAAGCTAATGAGAATATTTTGACTGTGAATAGAACCAAATATTTTTTTAAAAGCAAAGTCGGTTTTAGGGCTAATAAATTTCATAGTTATATATTATTTTGCTGAACTAGTATAATTTATTTTATACTATTTCATCATAATTAAAAAGCGATCGACACTTTTTCCGAGAATTATATAGAAAAATAGAGAAAAAAAAGACTCTTTAACTATCAATTATTCATTATCAATCATCCATTATTAGCTAGCCAGTTTTCTAAGTCTGCTATTATTGCTAAATCAAAAATTTCATCACCTAAAATATCTAACTTTTCCAAAGATAATTGCTCTATCTGAGTCTGAACTTCTGGAGGCACTTCCCCAAACTTCCGGCGAATTTGACGTTTAACTAATATTCTCATTCCTTCCTCTCTTCCAATTCCAATGCCTTCCTCCCGTCCAATTCCAATACCTTCTTCTCTTCCAATTCCAATACCTTCTTCTCTTCCAATTCCAATACCTTCTTCTTTTCCAATTCCAATACCTTCTTCTCTTCCAATTCCAATACCTTCTTCTCTTCCAATTCCAATACCTTCTTCTTTTCCAATTCCAATACCTTCTTCTCTTCCAATTCCAATACCTTCTTCTCTTCCAATTCCAATACCTTCCTCCCGCCCAATTTCTATTCCTTCCTTTCTGGCTAAACTAATTTGTCCTTTCTTATCTCTAATCAACTTTTCTTGTTGCTCTAATTCCTCTAATTCTTCATTACTTAAGTTAGCCATATTTGCTATATTTAATGCTGACTCTATTTCTGATACCTCTTCTAAAGAGGAAGGTATTACTTCTAAATTTGGAGCCGAGCTAATAAAATATATCCACTTATCACTGAGGGTTTCTAATACTGACAATTCTTTCTTAAATTTGGGTAATTCTACAAACATTAAAGTTAATTCATCTTGGTAATTAAACAACTCCGTCTCTTCTTTAAATCGGAATTTAGTAATCATTTTATCTGTGTTTTCAAATAAAACAAAATCAGCGATTTTTAAAGCTACAAAAGGTGTCAACATCATATAACCTTGCCCTACCTCTAATTGATTTCCATAAGCTTTAGCTAGATTATAAATTACTCGTTTTTCAAAATCTTCTACGTTTAATACTTGCATTTCAATAATCACAGTAGAACCATTATCTAAAACTGCTTTTACATCTAAATAAGTCTCTTTGATAGTGTTCGTAACTCCAGGATTATAAGGATTAATTATTTCTAGAGATTGAATAATATTCTGATTATTATAAACTATAGCATTAAGAAAGCTAATGAGAATATTTTGACTGTGAATAGAACCAAATATTTTTTTAAAAGCAAAGTCGGTTTTAGGGCTAATAAATTTCATAGTTATATATTTATTATTTTGCTGAACTAGTATAATTTATTTTATACTATTTCATCATAATTAAAAAGCGATCGACACTTTTTCCGAGAATTATATAGAAAAATAGAGAAAAAAAAGACTCTTTAATTATCAATTATTCATTATCAATCATCCATTATTAGCTAGCCAGTTTTCTAAGTCTGCTATTATTGCTAAATCAAAAATTTCATCACCTAAAATATCTAACTTTTCCAAAGATAATTGCTCTATCTGAGTCTGAACTTCTGGAGGCACTTCCCCAAACTTCCGGCGAATTTGACGTTTAACTAATATTCTCATTCCTTCCTCTCTTCCAATTCCAATGCCTTCCTCCCGTCCAATTCCAATACCTTCTTCTCTTCCAATTCCAATACCTTCTTCTCTTCCAATTCCAATGCCTTCCTCCCGTCCAATTCCAATACCTTCTTCTCTTCCAATTCCAATACCTTCTTCTCTTCCAATTCCAATGCCTTCCTCCCGTCCAATTCCAATACCTTCTTCTCTTCCAATTCCAATACCTTCTTCTCTTCCAATTCCAATACCTTCCTCACGCCCAATTTCTATACCTTCCTTTCTGGCTAAACTAATTTGTCCTTTCTTATCTCTAATCAACTTTTCTTGTTGCTCTAATTCCTCTAATTCTTCATTACTTAAGTTAGCCATATTTGCTATATTTAATGCTGACTCTATTTCTGATACCTCTTCTAAAGAGGAAGGTATTACTTCTAAATTTGGAGCCGAGCTAATAAAATATATCCACTTATCACTGAGGGTTTCTAATACTGACAATTCTTTCTTAAATTTGGGTAATTCTACAAACATTAAAGTTAATTCATCTTGGTAATTAAACAACTCCGTCTCTTCTTTAAATCGGAATTTAGTAATCATTTTATCTGTGTTTTCAAATAAAACAAAATCGGCGATTGTTAAAGCTACAAAAGGTGTCAACATCATATAACCTTGCCCTACCTCTAATTGATTTCCATAAGCTTTAGCTAGATTATAAATTACTCGTTTTTCAAAATCTTCTACGTTTAATACTTGCATTTCAATAATCACAGTAGAACCATTATCTAAAACTGCTTTTACATCTAAATAAGTCTCTTTAATAGTGTTCGTAACTCCAGGATTATAAGGATTAATTATTTCTAGAGATTGAATAATATTCTGATTATTATAAACTATAGCATTAAGAAAGCTAATGAGAATATTTTGACTGTGAATAGAACCAAATATTTTTTTAAAAGCAAAGTCGGTTTTAGGGCTAATAAATTTCAT

Protein sequences of DBSCAN-SWA_7

>NC_008312|4838317:4949144|4909004_4910381_+|WP_011612675.1|DBSCAN-SWA
MFISSEGIIKLQKYFKQKVFFGNEPTPELIAILLVYFVQGILGLGSLAISFFLKDELAMTPAEVSAMLGIVIIPWMIKPLFGFITDGVPILGYRRGPYIIFSGILGAFSWVALATWVDTPLTATVAIAMSSLSVAMSDVIIDSLVVERVQKESVSNTGSLQSLCWSASALGGLITAYFSGYLLEHFSPQTVFLITATFPLIVSLVPLLIEEKKVSIRINFDNVKQQIKQVKKAVIKKSILLPTAFLVIWQATPNSESAFFFFSTNELGFQAEFLGRIRLVTSIAALFGVWLFQRFFKSVPFRKIFGWSTVISALLGMTTLLLVTHTNRTLGIDDHWFSLGDSLVLTVMGKIAFMPVLVLAARLCPPGVEATVFALLMSIYNLAALISHEGGALLMHWLKVTETNFDNLWLLIVITNLSTLLPLPLLNWLPTANAQTDEEENLNSQPILEPESSEIISR
>NC_008312|4838317:4949144|4926404_4926803_-|WP_155994450.1|DBSCAN-SWA
MRECNSISIVKNNDTENLSQLDSIDQKVGLQNWLEKSCQLSQLNYDESSSSPPTDTQTILKDTHRFKRTKNQYDGRTIYEEKETGYLWYVDNLHYGKSAHLEVFDNTGKNHIGESDLEGKIDRTKSDIKKSI
>NC_008312|4838317:4949144|4847766_4848852_-|WP_011612647.1|DBSCAN-SWA
MKIGIPKEIKDQEFRVGLTPASVKVCTEAGNEVFIETEAGWGAGFSDSDYLNAGGHILSDTRDVWKCDMIVKVKEPLSSEYEFLKSEQLLFTYLHLAADRKLTKKLIESGVTAIAYETVELSDQRLPLLTPMSIIAGRLSVQFGARFLERQQGGRGVLLGGVPGVTPGKVVILGGGIVGTEAAKIAVGLGAKVKILDINLERLAYLETVFGSRLELLYSSSSAIEAAVADCDLLVGAVLVPGRRSPVLVPKSLVEQMHSGSVIIDVAVDQGGCVETLRPTSHTNPIYQELGVVHYGVPNMPGAVPWTATQALNNSTLPYVLQLANYGSKALDMNPGLAKGLNVKNHVLVHPALREVFPDLN
>NC_008312|4838317:4949144|4896942_4897173_-|WP_011612669.1|transposase|DBSCAN-SWA
MNNGKINLGKIVIEIIEEVGASLLFLSPYSPEFSPIENFFSKAKAILRRVKVRNYQGLIDAMTSAIFKVSQKDIRN
>NC_008312|4838317:4949144|4932297_4936287_-|WP_011612687.1|DBSCAN-SWA
MFTSVKPTVRHIVPADLKGRSLLKVVYIVLEAQYQSSLSAAVRSINEKNPNLAIEISGYLIEELRDPKNYENFRREVSEANIFIASLIFIEDLAEKVVEAVTPHRDKLDAAVVFPSMPQVMRLNKMGTFSMAQLGQSKSAIAQFMRKRKEKSGSSFQDGMLKLLQTLPKVLKYMPLDKAQDARNFMLSFQYWLGGSSENLENFLLMLADKYVFKDQKKSSLQYVDPVVYPDMGIWHPLAPKMFEDVKEYLNWYNNRKDISENLKDPLAPCVGLVLQRTHLVTGDDAHYVAMLQELEAMGARVLPVFAGGLDFSKPVDAYFWEVVTKGVEPTPLVDTVISLTGFALVGGPARQDHPKAVESLKRLNRPYMVALPLVFQTTEEWQESDLGLHPIQVALQIAIPELDGAIEPIIMSGRDGATGKAIALQDRIEAVAQRALKWASLRRKPKLNKKIAITIFSFPPDKGNVGSAAYLDVFGSIYEVVKALKGNGYDIQDLPDSAEELMKQVIQDATAQYQSPELNIAYRMSVLEYERLTPYSERLHENWGLPPGNLNSDGENLLIYGKSFGNVFIGVQPTFGYEGDPMRLLFSHSASPHHGFAAYYTYLEQIWKADAVLHFGTHGSLEFMPGKQIGMSGHCYPDNLIGNIPNIYYYAANNPSEATIAKRRSYAETISYLTPPAENAGLYKGLQELNELIASYQTLKDSGRGVPIVNTIMDKCRIVNLDQDVTLPEKDAQELTAEERDQVVGDVYRRLMEIESRLLPCGLHVIGKPPTAEEAIATLVNIASLDREEEGITGLPRIIANSLNRDIEELYQNNNKGILADVELLQNITEGTRAAVAALVHQQTDAEGRVSMVGKLNFFNMRKKAPWIEALEAAGFPDVDEEAIKPLFEYLEFCLEQVCADNELGSLLRAFEGEYILPGPGGDPIRNPDVLPTGKNMHALDPQSIPTAAAVKSAKTVVDRLLARQMQENGGQYPETIAVVLWGTDNIKTYGESLAQVMWMVGVKPVPDALGRVNKLELIPLEELGRPRVDVVINCSGVFRDLFINQMNLLDKAVKMAAEAHEPEEMNFVRKHALKQAEDLGVNLRQAATRVFSNASGSYAANVNLAVENSTWEDESELQEMYLKRKSFAFNSDNPGMMEDNRKVFESALKTADATFQNLDSSEISLTDVSHYFDSDPTKVVATLRGDGKQPASYIADTTTANAQVRSLSETVRLDARTKMLNPKWYEGMLSHGYEGVRELSKRLVNTMGWSATAGAVDNWVYEDVNETFIQDKQMQQRLLNLNPHSFRKIVATLLEVNGRGYWETGESNLDRLRELYQQVEDRIEGIE
>NC_008312|4838317:4949144|4928194_4929331_-|WP_011612685.1|DBSCAN-SWA
MTKSVILYLESVSKKFSRSTTTAVQNVNLTLYQGDILGLLGPSGCGKTTLLRIIAGFEEPQSGIVTINGRLVAGKHDWIVPEKRNVGMVFQDYALFPHLTVAKNIAFGLHNSGKKSSTQINHQVRDVLELVGLSDLENRYPHELSGGQQQRVALARALAPNPALVLLDEPLSNLDVQVRIRLRQELRDILKNAGASGIIVTHDQEEAMAISDRVAVMRAGSVEQFGTPKDIYTEPASKFVAEFVTQANFLPAHRHDQVWETEVGAFELTNNNVFGGEIDSLDEFDRLELMIRQEDLILKADNEGCIVIRDRQFLGREFRYCLQTESGKELIARTTPQVALKIGVKVKVSIAEDNLRVFPTTAEEKPEKSSDLVGSRNF
>NC_008312|4838317:4949144|4849312_4849498_+|WP_011612648.1|DBSCAN-SWA
MLYSLDFRQKVINFVENGGMLTKVTHVFGIARASIYRWLSRPKLEATKVKCRLIKLDWKEL
>NC_008312|4838317:4949144|4891994_4892129_+|WP_011612667.1|DBSCAN-SWA
MERTKSQKLIDIITIIISDVICGVDTWIDIKSYGKSKSEWLKSF
>NC_008312|4838317:4949144|4904812_4905010_-|WP_081432470.1|DBSCAN-SWA
MFHPLFCLGVSLLLLANSENFLRNGITVENIDHLEIVAGLIDEIGIVEIMNRKLGVDNSEKITSG
>NC_008312|4838317:4949144|4946699_4947848_-|WP_011612693.1|transposase|DBSCAN-SWA
MKFISPKTDFAFKKIFGSIHSQNILISFLNAIVYNNQNIIQSLEIINPYNPGVTNTIKETYLDVKAVLDNGSTVIIEMQVLNVEDFEKRVIYNLAKAYGNQLEVGQGYMMLTPFVALKIADFVLFENTDKMITKFRFKEETELFNYQDELTLMFVELPKFKKELSVLETLSDKWIYFISSAPNLEVIPSSLEEVSEIESALNIANMANLSNEELEELEQQEKLIRDKKGQISLARKEGIEIGREEGIGIGREEGIGIGREEGIGIGKEEGIGIGREEGIGIGREEGIGIGKEEGIGIGREEGIGIGREEGIGIGREEGIGIGREEGMRILVKRQIRRKFGEVPPEVQTQIEQLSLEKLDILGDEIFDLAIIADLENWLANNG
>NC_008312|4838317:4949144|4860318_4862109_+|WP_011612652.1|DBSCAN-SWA
MAKYSTILDILNHRSQNLPDQIAYTFLPDGETESGHLTYQQLNVQVRAIAAHLQSFITLQDRILVIYPYTAGLEFIASFFACICAGAIAVTSNPPLNNEAIAKLQERVDSCQPKAILTTESFLQQIKKKLAKNLDLAPKLNQLPWIATDKISSSEAPKWKEPKIEPDTLAFFQYTSGSTGKPKGVMVTHSNILHNSEIIYQSFEHSAESQGVIWLPMFHDMGLIGGVIQPLYGGFPVTLMSPVALIQKPIRWLKAICKYKATTSGGPNFAYDLVSRQVTPEQLQNLDLSSWSVAFSGAEPVRAATLERFAHTFAPCGFQREAFYPCYGMAETTLFISGGTKTKAPVIQYVDAEALAENRVVVGRENSKPVVSCGWGWLGDEIAIVDPKSLARRSQGEVGEIWVSGAGVSKGYWQQPEETEQTFNGFLADKGPFLRTGDLGFLQDGELFITGRIKDVMILWGRYRYPQDIELTVEKCHPALRSGCGAAFSIEAEDDERLIIIQEVERSYLRNLNFEEVVGAIRQAVAEEHTVEVYTISLLKTGSIAKTTSGKIQRRLCRSQFLEGTLNSVGNWQLQAEKGSVSELANNSNYIDSENS
>NC_008312|4838317:4949144|4899214_4901035_+|WP_011612670.1|DBSCAN-SWA
MLIEILTLFAGAGLEQATSVTWHWASKWAAKKADEKSQVIQTALLTSYCKALQVIRKESQQLPQWKQEKAEIQARLTEMEKDALMILDLAQTQKHRMTSIPQGGEEQAITKTVMSRLQSKDKWLKHAPKELSYLVETRLVSITVHQFRHELRTESRVFQALVHDMLATAGEDVSRLLDVTNRIEKRVDQFVGDYRQDIDRIIVGIGGANSHLEQLISLLSRQMKQSQAIPADFAALIADKTEGFLGRGFVFDTIENFIQNQSKGYLIIEADPGVGKSTIIAEYVRRTGCIVYFNLLSEGRTRAEDFLKSVCTQLIERYNLPYELPLHPDNTSNGNFLSKLLNEISIQLLPKEKLIIAVDALDEVDLSSQSGAANVLYLPANLPNRVYFLLTKRSDPLPLVVSAPQKIFDLMIYPNESLKDVKLFIYLRTKRTTVQAWIKTRGLTLEKFVESIASKSENNFMYLKYVLDDIEQGSYRDISLESLPQGLEKYYDQHWHRMKMNVKPLPITKLKIIYFLTKTRKPVSCGMLAKFSGEISLTVQEILDEWAQFLRIHQTEGKPVYSIYHAAFQDFLYRKDIVQEVESLVEIESMEKQIKNNLLGMVYKNG
>NC_008312|4838317:4949144|4893090_4893198_-|WP_081432551.1|DBSCAN-SWA
MDIITITICDVICGADIWIDIESYGKSQSEWLKSF
>NC_008312|4838317:4949144|4882296_4883631_+|WP_011612662.1|DBSCAN-SWA
MTSSPYKSKVLNFVVAKYNQILTRSDRTLCHLKFIATITVQLLLYPIYVLLQTSRVALKKLQQTTKSYLPEIKEKVNKNYQTNDKSIEEVSVFSRPVDSRLLYPLNPNKTLVKKQGKVSSRLEILNNYKVSDILTRAKQENPLILDMGKIEEKPLLQLQIQPCAELVPTFGVLGGVWQLMAWVQTSEIALWFNFFDESNIVLQQNELKDNNRSLNSYHNQVLLSNSNITFGEFINNLAKHYLYPITKGLGLNGLLLPLRREGECEVESLLETEIDPENQKNLLATQDGTPIVASLISPFEQGIFQIATSSTTKPLMNPEDVEKPGKKKSFPLHKHLCYEIISSSNDYLKQEAIASKEALREIDGHRVENEDNYSINSNKISVKTYNSESKPKEKLNCLEVESVSVGYIKHPLEVILGWVDVIMTWVEKIFVQAWQLCQQKLKNF
>NC_008312|4838317:4949144|4865768_4866434_+|WP_011612655.1|DBSCAN-SWA
MTSQTCQLICPGLTKYSVAWEWQRSLVQQRHNCPELADVLILLEHPQVYTLGQGAKLDFLKFDPTQNKYELHRVERGGEVTYHCPGQLVGYPILNLKHYQQDLHWYLRQLEEVLIKVLDIFGLKGERYPGLTGVWLEGRKVGAIGIKVSRWITMHGFALNVSPNLEGFQRIVPCGISDKSVGSLAQFIPSITTDEVLPLVANAFAKVFGVKLVKSTNAILF
>NC_008312|4838317:4949144|4843237_4843441_+|WP_044136852.1|DBSCAN-SWA
MALPFKVKINETLSELEKCLSKSITAKGKERIQMIYWLKTNLVSTRREQALLLSRYESMITRWLINS
>NC_008312|4838317:4949144|4849528_4849606_+|WP_071820760.1|DBSCAN-SWA
MADRAKKIGVNPTAIFYTLKRMNFP
>NC_008312|4838317:4949144|4917941_4919216_+|WP_011612678.1|DBSCAN-SWA
MTNDRPLVDLEKALEVIQSQANSLHVVVVGKIKGFLDPEVLMRSLLLVQLRHPLLNSHIVGPLDNLIFKTEGTEKIPLEVIFNSEPEYWQTIFVNELNTKLENQKVLLRATLIKPTEKSTTNYLITRIHHAIIDGISAVHLYSEILSFCQKIVSENQIPEVEKLAPPPCFEKIIADYNIQNNTESLISELGQPIDTLPFEKYVPYKQRTCGLIQKQLNASLTQQLIQHCKSEKVTVQGAICSAMMLALAKNLEPEDKEFSFSCYHAVDMRKRLNYPIGNEQMAFLVSSLLCFHKVNQKMSFWGLARQATEEIKAKLKTPEIYHRVLFFSEAINMILKNPEKTISSIFVSNIGKVKISSKYGQFQLEEISFGSSNKMFGSTFNVSVSTFQDQITFNFIYTQPLVSQTVIEKLVKDSIEYLVTSCN
>NC_008312|4838317:4949144|4931977_4932190_-|WP_071820761.1|DBSCAN-SWA
MSNNLIEISPEILSGTPVFKNTRAIFKTLIDYLSAGETIADFIDDFPTVTQEQAISLLKLAQETLLKQTY
>NC_008312|4838317:4949144|4943407_4944664_+|WP_011612691.1|DBSCAN-SWA
MALTIDKLFDEQFYLETHPGVAEAVANNIISDGFFHFTRFGQFEDRDPSRIFNTNFYLTTNPGVATAVEQNILTPTEHFINFGQFEQRDPSALLNTSFYLERYPDLAEVVVNTPLTATEHFLNFGQFEGRLPRLLFSDIYVFGDSLSDTGNLLAAAENFLGATDEFVLEFFAPYFEGRLSNGPVWVETLAPQLELTSDPNLNFAVSGATTGISNNGNNRLPEGTPPIFIGLQTQIDDFIADTPTTDPDALYVVWAGANDYLGAGNLDAQSTVDNLLDAVNSLADTGAKNFVLPNLPNLGVIPVGQALPPERQQGLTLLTESHNNTLATASQILEQNPNINIVNLDIKTLFDNIIANPDDFTLTNVTDNFLTSGLDDPSGFLFFDDIHPTTNVHSFIAENTMKSITQIPELLSIVETSL
>NC_008312|4838317:4949144|4907276_4908824_-|WP_011612674.1|DBSCAN-SWA
MFQTTRRRLAIWYTTVTAILLLIFTTGFYIYFRSTLIERIDDTLLHVVEIVERSLVIEPIIEPIPNFPIGNSENFRVNLEVSFRDNANTVEDDHIDIEWFSPTGELLWSTFSEPLNIPIHSNRIGETVRIIPHSGKIETLQPIIDNSLLLRQVTDRVEVGRQVLGYLRVSHPWFEVTKPIRLLMLDLSIGTCLVLISVGGIGWLLSGLAIQPVRESYQHLKKFTADASHELRNPIAMIQTNVQVALADPKLVSSEHQQQLQVIERLTRRLGRLVDDLLFLARQDSRMVQSEFSPVPIEALLMEVVEEQQAIATAQGINLELKISLPDFIGENSIFNQNSTLNYKHHGKIDNSKIIKHPIFEEDITLIGDWEQLARLFTNLISNGMQYTQSGGHLVVELQYLPKAKKPMLRTQDGELGNTSKNSGVIFRGCQNIKNDCLQVTVKDNGIGIPTEALSRLFDRFYQVDSARSHGGIVGSGLGLAIALAIVENHCGQISIESCPQVGTMATVILPLHQS
>NC_008312|4838317:4949144|4845807_4846593_-|WP_011612646.1|DBSCAN-SWA
MLTSLQNSLVKQIRQLHQSKGRQEQQLFLVEGTHLLEEACKRNYPLITVCHTFEWQEKHKFLYELVSQKAQRIELVSTKIIQSLATTVSPDGVVAIAPQSQTNFLKITTLGIVLDKIQDPGNLGTIIRTAVATNIDGLFVSRDSVDLSHPKVVRASAGEWFNLHKAISENLKNEILKLQSQGLQVLATVPNSNINYWEIDLRKPTIIVLGNEGSGISKDLIDLADYSVKIPLSNGVESLNVAVSAAIILYEIQRQRQLELK
>NC_008312|4838317:4949144|4838317_4839355_-|WP_011610086.1|transposase|DBSCAN-SWA
MNIIDKLNDFINQTKESKEIKRALAVKMTLSGKSYHEVKELLNVSHSFISEWKNQALFHGVESLRLQYQGRQGYLKTVEKEKTIEWLRAQDYLRLSDLKNYLQEQYDVVFESNQSYYNLFKEAGISWKKTQKKNPAKNDELVEVKRKEIEEFLAKWQPEIETGKLTVFMIDECHLLWGDILGYAWGKTDERIEIAIKNEKERQTYYGALDYKTKEFLVQEYESGNTKNTIEFIKYLQKQRPGNKLAIFWDGATYHNSQEFREYLMTINQYLSEEELLINCTRFAPNAPEQNPVEDIWLQTKNFSITFYHLCSSFKVVKWLFKFFADGQIFNFPKLFQYEILPQPT
>NC_008312|4838317:4949144|4844297_4844447_+|WP_081432550.1|DBSCAN-SWA
MQIFFINSIGIKICHNKGSKRNKVFNGLGKWVKSTVDWYLGFKLDLIIN
>NC_008312|4838317:4949144|4890615_4891140_+|WP_011612666.1|DBSCAN-SWA
MNIIDFFELSAGEWFSQRTIHNLVSGELQAGKSEVNVEILEKTDPTLINLCEQNQVDSSVTKLIGVKISWNGTNNKGQVKDVGSRMLIIIPNFDDLNQGQLLQNRGNGNSPKISGRYIMGSDDVLMLTTESEGLYVEERFWYLIPNLRLRTSVVNRPQGFSLASFCSEIRRVKS
>NC_008312|4838317:4949144|4874833_4875961_-|WP_011612660.1|protease|DBSCAN-SWA
MNGSFRVGNLFGIPFYINSSWFIVLGLLTLTYGNDLATQFSQELGNTLPWILGLITALLLFSSVLAHELGHSFVALYQGIKVKSITLFLFGGLASLDRESKTPIEAFLVAIAGPLVSILLCGFFVSINIFTSITGPAESIVQLLAYINLFLALFNLIPGLPLDGGNILKSIVWKITNNPYKGIIFASRVGQVFGCLAIISGLIPAFLFSRIPNFWNILIGWFLLQNAGRSAQYGEIQGMLADLNAVDAIIPDNPIVSNNLSLREFVNEYVIGKEARKKFLVINEMGQFVGVINVDDLKIVNTSQWPLVQVKTLTKPLAKIETVTAKTSLLEVISLLEQKQISELTVIDENGILVGSIEKASIRRLLTRKEQAKTN
>NC_008312|4838317:4949144|4906361_4906856_-|WP_155994449.1|DBSCAN-SWA
MIITISQAGGPPPDTKPPIVNQQEDTSNSSNHRGKPVKVEPKTTKPTHRQSPTQQSETTDSPPDRIRSDLGLITLRLINQTGAIIEYQVIGGQYMTLGGTSVVELSKLSIPLTLTYQRPDGGLILVRYQSISPTVLEVIFHPTEDFDLDTNSLNISGKGQISLN
>NC_008312|4838317:4949144|4937985_4938924_-|WP_011612688.1|DBSCAN-SWA
MKYIDYSVVIPIFNESEIIPELWRRLSDILDKLDSSSEVIFINDGSVDNSLELLKEINHKNQKVKIISFSRNFGHQCALSAGIDHANGKAVILMDGDLQDSPEAIISFLRLWQQGYDVVYAIRKNRKEKWLKRLAFKSFYYIQRKLSGIVTPMDAGIFSLMDRKVILTLRQMPERNKYLSGLRAYAGFKQIGVYVERGPRYRGEPKMSVSKLFKLAFDGIFSFSTIPLKMATILGLVSAILSFIIGLIGLYVKFILGKEFLSWAYGLTTTFFMGGIQLLSLGIIGEYIGRIYDEVRQRPYYIIQEKIGFEKQ
>NC_008312|4838317:4949144|4854322_4855660_-|WP_011612650.1|DBSCAN-SWA
MQTFVFIWLGQVFSLLGSSLSEFALAVWVYQTTGSITHYALLSLFIHLPSIFISPFAGAMVDRWSRRQAMIVSDSITGVTALAIMFLVFSQQLQVWHIYIAVGISSVCNAFQWPAYISVIPQLVPPKHLSRANGMVQGAIATARILGPSIAGVLIIKIHLHGILLIDFSTYLLAFFTLLSVKFPISQQQKIRRKVSIEKLWQEVISGWNYVVVRTGLRQLTIFFGVIYLSAGILQVLFLPMVLSFASEKELGIVMSVSGIGMLLGSVIVSLWGCSKRRIEGILVFVFIQGLCLCLGGLKPAVILAAIGGFGYLCSRAIVVSLNHTIWQQKVPQYLQGRVFSLQNMMEKFLLVITHLSAAPLVEFMFKPLMSENGILASSVGRIIGVGDGRGIALLFVLMGLLNIGAVLVAYRTPQLRRVEIELNDTDRFQVNKTETDNTEQTVLM
>NC_008312|4838317:4949144|4839781_4841212_-|WP_011612645.1|DBSCAN-SWA
MTQEFDYDLIIIGAGVGGHGAALHATSCGLKTAIVEVAEMGGTCVNRGCIPSKALLAASGKVRELRNAHHLKTLGIELDNVSYDRQVMATHASNIVTKIRGDMSKSLKRLSVDIITGWAQVAGKQKVTVKTEKGEENFTAKDIILAPGSVPFVPPGIELDGKTVFTSDDALKLDWLPPWVAIIGSGYIGLEFSDIYTALGSEITMIEALDKLMPTFDPDIAKIAQRVLIQSRDIEVKVGKLAIKVVPGSPVIIELADAKTKEVEEIIEVDACLVATGRIPYTKDLGLDSVAVETDKYGFIPVNSKMAVLSSGEPVPNLWAIGDATGKMMLAHAASAQGITVVENICGRDREPDYLSIPAAAFTHPEISYVGMTEPAAKDLGQKQGFEVASVRTYFKGNSKAIAEDETDGIAKVIYRQDTGELLGVHIIGLHASDLIQEAANAIAKKQSVNELSFNVHTHPTLSEVLDEAFKRATVH
>NC_008312|4838317:4949144|4866531_4867038_-|WP_011612656.1|DBSCAN-SWA
MNSCILMVQITKDPELRYTADSQLPVAEMIVEFPNLGVNNKPALLKVVAWGDLAEQVNEKYHQEDYVIVEGRLSINTIERPEGFKEKRAELTASKIYPISSEAMTQDENQMPTNKSSKRNFTKQQSQEEQYSNVVDLKSRLSSTVNEESKTDLVESELPADDFDPIPF
>NC_008312|4838317:4949144|4887964_4888147_-|WP_044136854.1|DBSCAN-SWA
MIRVEKKENTVVFLLELSCIPWAVNDDFVWKLVEILMILNSHKFRHYRKGIKAINKLFNK
>NC_008312|4838317:4949144|4927312_4927558_-|WP_011612684.1|DBSCAN-SWA
MSRFCDNLYRLLINVVEEKKIKEKAKKVIQKIQSTKTSLIPRSISLFQYFISILISDKIIDVSTNKYYFHITKEVIDLSNG
>NC_008312|4838317:4949144|4895023_4895446_-|WP_052845813.1|DBSCAN-SWA
MDKIALSLSKNAFQAVTLEQDIPKKVWVATIKLETKGLTGYRTIAVIINSIYIKETSKIDYLITNKQYKSVSRALILTKYLNRNYIEKNYIKAKIKLGLKEHQIRDKTSFMRHCILVFFSYPFISYQQLMVGVIKRYSCK
>NC_008312|4838317:4949144|4929943_4931611_+|WP_011612686.1|DBSCAN-SWA
MLGQMKKFNRLNWNASTIFVVAIACLISAPVVFVLSSIFSDTGEIWSHLASTVLPRYLLNSFILMLGVGCGVSIIGVGAAWLITMCRFPGSRIFEWAMLLPLATPAYILAYTYTELLEFYGPVQMWLREIFGWTSISDYWFPQIRSLGGAIALLTLTLYPYVYLLTRVAFLEQSTCTLEASRSLGANPWRSFFTIALPLARPAIMAGLALALMETLNDFGTVQYFGVDTFTTGIYRTWFGMGERVAAAQLAAMLLLFILWLILLELWSRRQAKYYQTSSQQQNLQQFPLDRIRGIATSFACLLPVFLGFLLPAGLLLEMTITESGASFRGRFWDYASHSLTLAGITAILGVAIAVIMAYGVRLNQNLGMRISTRIAAIGYAVPGSVIAVGILIPIGTVDNAIDSFMRSMFGISTGLLLSGTITALVFAYLVRFMAVAFGAVESSLVKIKPSLDDASRSLGYGSTKTLIKVHVPMMWGGLLTGAMLTFVDVMKELPATMVIRPFNFDTLAVRVYNLAADERLTEAAGPALAIVLVGIIPVIILSLKIAKSRQYQDY
>NC_008312|4838317:4949144|4857112_4858336_-|WP_044137604.1|DBSCAN-SWA
MKIAIIASGFLPVLDGVTVSGYYRVQKLSQFGHQVLLFCPDYSPLAHLYPNWKDYTGNIFPGIQVINLPSTPFLDFERNVGFNTYKIVVRELEKFQPDIIHVDEPERLFFAFFRLAGIKFARENNIPCICTFRTNFLEYFEDFLPLPKGINLMLQLIFEKSFVSIYNKYDLTLVSSTITHQKIIGMGIKNAMYINFHGFDIEKFNSATITTNFWELNYQIPNLNNKVKIVFLGRLTEDKGWKFTLGAFVKLQQLVNIENVAIIIVGDGPMREEISNRLSQVTNHVYLLGRISPKHIPNILKNSNFHVTASEKETRGLTVLEAFAAGIPVVAPEAGGVTENIQNGRNGLLFTPGNQESFCDKLKLLIEDSNLRKEMGINGRETISKYSWDNAVANLVKIWQEQIILQS
>NC_008312|4838317:4949144|4945575_4946556_-|WP_011612692.1|transposase|DBSCAN-SWA
MKFISPKTDFAFKKIFGSIHSQNILISFLNAIVYNNQNIIQSLEIINPYNPGVTNTIKETYLDVKAVLDNGSTVIIEMQVLNVEDFEKRVIYNLAKAYGNQLEVGQGYMMLTPFVALTIADFVLFENTDKMITKFRFKEETELFNYQDELTLMFVELPKFKKELSVLETLSDKWIYFISSAPNLEVIPSSLEEVSEIESALNIANMANLSNEELEELEQQEKLIRDKKGQISLARKEGIEIGREEGIGIGREEGIGIGREEGIGIGREEGMRILVKRQIRRKFGEVPPEVQTQIEQLSLEKLDILGDEIFDLAIIADLENWLANNG
>NC_008312|4838317:4949144|4864217_4864865_-|WP_011612654.1|DBSCAN-SWA
MKLVIQGKNIEITDSIHEYVNQKIEKAVNHFQQLTTEVDVHLSVARNPRINPKQTAEVTIYANGTVIRAQESSENLYASIDLVADKIARQLRKYKEKRQSKVNKTKTVDLIESQPVVENLIGDRQAELPSEVVRTKYFPMPSMTVEEALEQLQLIDHDFYMFSNGVTGEINVIYKRYHHGGYGLIQPRPNGNDNGNNGKVSDSIGEAAGLKSTHI
>NC_008312|4838317:4949144|4888423_4888987_+|WP_011612665.1|DBSCAN-SWA
MTEKPLTSALAEALLTKYDFDLGGETSKQLIARWQKNYQVEWLSLAVIEALYLGRYKAISVQQILTLWERRGQPIYHFNSEFQNIITRNVITNFTTQIDTPSLSTKTNPSFLEEKLINHSKLTSLPSNPFEPNLKNKTQNLMQQQVPVEPYQNKIKHTDFYTKLKTVLKKSQALQSYPKELEPENDK
>NC_008312|4838317:4949144|4850498_4851890_+|WP_011612649.1|DBSCAN-SWA
MPLREDRAINQQLHSIADTDKLKSSPVNQSILKIWGPSRLKGNISISGAKNSALPAMAATLLSSGVCRLRQVPCLADINIMGQVLSALGARIKHNTNTFTLDIDASIINHHEAPYELVRQLRASFFAIGPILARLGVARVPLPGGCAIGARPVDLHVRGLQALGAEVHIEHGMVNANISGSKKRLQGAKIYLDYPSVGATETLMMAATLAEGETIIENAAKEPEVEDLANLCIAMGANIFGAGTKRIVISGVPKLHSVDYTIIPDRIEAGTFLIAGAITNSDISISPVVPKHLSAVISKLQSVGVKVIQETSDSLRLLPSEILKSTNIKTQPYPGFPTDMQAPFMALLSVCSGTSDVTETVFENRMRHVSELNRMGANIRVKGNHAIVKGVPKLSAAPIIGTDLRASAALILAALAAEGETTFQGLQHLDRGYEQLEIKLQKLGAKFERVDLVEENEIFQASI
>NC_008312|4838317:4949144|4883739_4883856_+|WP_011612663.1|DBSCAN-SWA
MLTLKIVVNIVVLFFVLLFIFGFLSNDPARNPSGRDME
>NC_008312|4838317:4949144|4901296_4903483_+|WP_011612671.1|DBSCAN-SWA
MGEFRENLVQLPLEDQRYLLETLPGFLVSECDTEQLHRLLTDFDFLESRLYLFGVEYLLNDYEEAMHSDAWISGEKLKTLKFIQGAIELSSHILVEDKTQLAEQLWGRLLSFEIPEIQQMLQQAKSWKVTSWLRPIAPSLTPPGGRLLRTFTGHSGWVNAIVVTSGGMVISGSSDNTLKVWNPETGKEISTITGHAARIRAIALLDDKWVISGSDDFTIKVWDLETTEELVTLTGHTRAVRAVAALSDGRVISGSSDNTIKVWNLETQKVEMTLRGHQGWVNAVSVLSDKEIISGSSDNTIKIWSLETGEELFTLKGHTDGVRTITTLLERQIISGAADNTVKVWNLDSKKAVFTFKGHSKEINAVAVTPDNKRMISAASDNTLKVWNLETGEELFPLKGHTESVYAVAVLPDGRLISGSDDFTLKIWSLDTSEEFCPMVGHTNRVNAAIVLPEQQVISAAWDHTIKVWNLNTTKSIYTLKGHTDRVNSVAALPNQRIISASDDNTLKIWSLKTAEELLTIVSDNRCIFAVAVTPDGKQAIACLSDQTLKVWNLETLEEIFLLRGHTDWVSAVTVTPDGKQVISGSFDKTIKVWSLATRKEIATLVGHTGWVKALAVTPDGKRVISGSFDKTIKVWCLETGQELFSLSGHTDWVNSIAVTPDGSLVISASDDNTLKVWDLETRQVIANFTGESSLECCAVAADGVQFIVGEASGRVHFLKLENYKNQV
>NC_008312|4838317:4949144|4941212_4942649_+|WP_044136858.1|DBSCAN-SWA
MEKVDIVILSNGPGELVTWVRPVVQELRQQANIDMRISLVLSPCPHATGKEVAIARSYPEVDRVQPPEFFWRFLLWGKTAENWHWYPQGVVLFLGGDQFFTVVVGKRLGYRTVIYAEWDARWWRWVDKFGGMKPEVFAQVPPKYADKFTVVGDLMNEVRSSNKLRAQDSEFRTQNSELVINSELRTQNSEFRISNELASENLEVRSNFSNPSKGESSVELIGLLPGSKPTKLSLGVPLTLAIAQHLHKIRPQTKFIIPVAPTLDLNTLANFADPEKNPAIEKMGGVGAKLLTPSLNRKKTDSRKQGAYFEIQNSHLVTTGGLKIELITRNPAYDLLSKCRLCLTTVGANTAELGSLAIPMIVLLPTQELDVMRAWDGLPGLLANLPVVGAAFATGINWLVLRKGQLFAWPNIWAKQEIVPELVGKLKPEVVAELVLEFLTHPEKLAEMRDRLCNVRGKPGAAQKLAEIVLSLSYGSQI
>NC_008312|4838317:4949144|4947995_4949144_-|WP_011612694.1|transposase|DBSCAN-SWA
MKFISPKTDFAFKKIFGSIHSQNILISFLNAIVYNNQNIIQSLEIINPYNPGVTNTIKETYLDVKAVLDNGSTVIIEMQVLNVEDFEKRVIYNLAKAYGNQLEVGQGYMMLTPFVALTIADFVLFENTDKMITKFRFKEETELFNYQDELTLMFVELPKFKKELSVLETLSDKWIYFISSAPNLEVIPSSLEEVSEIESALNIANMANLSNEELEELEQQEKLIRDKKGQISLARKEGIEIGREEGIGIGREEGIGIGREEGIGIGREEGIGIGREEGIGIGREEGIGIGREEGIGIGREEGIGIGREEGIGIGREEGIGIGREEGMRILVKRQIRRKFGEVPPEVQTQIEQLSLEKLDILGDEIFDLAIIADLENWLANNG
>NC_008312|4838317:4949144|4913652_4917567_+|WP_011612677.1|DBSCAN-SWA
MNIQKNQEYNYQIGNYLTANHPTYVIRAADKELFNTLKNGEYCYVLSSPQTGKSSLKVNTTQLLQAENIICIALDMSRVNNKTFTLDEWYDQVILALEKSFTFPRYFPELWWEEMANMPGDEKLFVFIEEVLLANTQDEKIVIFIDEVNDDSVFDPGGGSLGILISYCLQERANNPEFKRLTFALLGTTIPNNLVDICRPIELSSFKIEEVPHFVNRFQGMVKQPLKFIEEILFWSGGQPFLTQKLCQIVINYLRERNEEEDDNNVTLVEDLVGICVLENWDAQDYPAHFSKLENLLLKNIQKSTNHLEIYQQILKYGRLKLPSESNQRFKNHAIAHSKWEIKELLRSGIVKINQGFLEVYSPIYAEIFNQEWVQKHLLQRTKSVPKVTEEKIELNDSNAEAKTWQVEANVSNFEIPENQKNYSHNEINSEQKLLVNPFKLKNFNNQVTNFQLGENFSGLESQDNQKNQSNNIIDPEQKQLENLLDLNQFDSSVTNLNLEENISNLQLFENHQIQSNNLIHPQQKELETPGEKITHQKNNKNQVRDKKAKKLAISQHKLNIGIAGLVVVSLIAITGATWATKLFQEKQTQLQKAEYQLEQFKYELKEAQKGKELEHEGINALRQFETAEIEALISAMKAGIKLQELVKYGRPLQHYPATSPIFALQQIINNIHEKNQIPNIKNIAMSPNNQLLAIVSNDGTAKILEFSGEPISQLRGHQGKISQIKFAPEGNLLATAADDATARIWDFQGKQQVELKGHKGQIWEITFSPDGKLLATAGEDGTARIWDISGQKIAILKKHQGRILDITFSSDGKYLATAGWDGTARIWSPSGKQLAILKGHQGSVEKIIFSPNGKYLATTGWDGTIRIWRRSSGKLLSKLKGGVWNISFSSDGKRFVTAGEDGTANIWNVSGQLLGKLPGHQGTVTSISFSPDGQCLATAGNDGSVKVWDNNGNLLTYLKGHLGRVLEMNFSSDGQLLLTLGEDGTGRVWDLEANYEAKIQGNSEIFGGVSFSSNSEKLATVAVDGVTRIWDISGNLLTEFNGSLGMFGDMSFSPDGKYLATAGDNSQARIWQVLGGELIELEGEEGMAKQISFSFDGQRLATVGEDGVARIWNNSGERLVELKGHNGRVLDVDFSPDGKYIGTAGEDGVGKIWDSSFRLVSELKIVSSWMESIGFSPSGEYIATGDSNGMVKIWDFWGHQIADLKAHIGSVKNVTFSADEEQVISMGKDGMVRIWDITGRQIGQFENAKGLSLDGKYIATLADNDLELWQVKGLNDLLKSSCNWLEDYFITHPDVRKDLEVCE
>NC_008312|4838317:4949144|4905457_4906150_+|WP_011612672.1|DBSCAN-SWA
MLKTEFSYKFPESNHPIVKSLFHHSDQELLTLFQNYPDEGKYFVTIFCRYGMIVQTLIQHSMRSPVQADYLFAQTWEHIFYELRGLDLREGVDPETGNTTLQNWLINVTGTTINQVEVPPVESIRYSLEMAPPPLWCYVRLVLAQLKPLLRLITLMFQTFHWSETRIAAYLQAEGETISPEEVKSLLEQGYHDLDSNLPEDIKTIYFNDDIEQVSIGINQFFKVPKQPEN
>NC_008312|4838317:4949144|4869557_4872089_-|WP_011612657.1|DBSCAN-SWA
MRGVLMAGGSGTRLRPLTCDLPKPMVPILNRPIAEHIINLLKKHQIREIIATLHYLPDVMREYFQDGSKFGVQMTYSVEEEQPLGTAGCVKNIAELLDGTFLVISGDTITDFDLSAAIEFHQKHKSKATLVLTRVNNPIEFGVVITDEEQRIKRFLEKPSTSEVFSDTVNTGTYILEPEILDYLPSNQECDFSKELFPLLLDKNEPIYGYIAEGYWCDVGHLDSYRKAQYDALQHTVKLELPYKERSPNLWIGENTYIDPTAKIETPTLIGDNCRIGPRVHIELGSVIGDNVTIGADANVKRPIVWNGTLVGEDTNLRGCVICRGSRIHRRAQILEGAVVGSLSTVGEEAQISPHVRVWPSKTVESGAILNINLIWGTTAQRNLFGQRGVQGLANIDITPDFAVKLGAAYGSTLKNGSTVSVSRDQRNISRMVSRSLIAGLMSVGINVINLQSTAIPIARTILPTMNLVGGLHVRLSPDRSDQILIEIFDYQGINISKVKEKNIEGAYFKEDFRRVQISEIGNMIDRHEVLNAYSKGFENLLNSEAIRYSKSKVVIDYCYGVSGAVLPQLLTKFGCDAVVLNASLKETSLGIEERENLLDQLGRVVEALQANVGVQVTANGEQLILVDEVGSAIRGETLTALMVNLMLTAHPRGTVVVPINASAAVEQIAHRHDSHVIRTKANPTALMKACQINHNVVLGGSGDMGFIFPKLHPGFDAMFCIAKVIEMLTIQERSLGQITADIPPITHRCYTIRCPWKVKGALMRYLVETNPPEKLELTDGVKIINHQDNYWVLVLPDAGKPLVHIYADSNDRDWVDKTLRDYRNMIHDFVNLFMTRNQLDNL
>NC_008312|4838317:4949144|4889679_4889940_-|WP_081432469.1|DBSCAN-SWA
MNTTKSGIRGASNNTNNLIIELIVTLSCLFRLPGRKTQGFIESIFHLMGLDLPVPDHSTVFRRVPQIKYHDTSYANHRRDSFSSRS
>NC_008312|4838317:4949144|4873162_4873363_+|WP_044137606.1|DBSCAN-SWA
MGTIISLLLLVIYGGGAWKFWNGFKQTNFSQSFQSRLVLSILWPVLLIGNKSYRKNFTKALKGNRR
>NC_008312|4838317:4949144|4884646_4887262_+|WP_011612664.1|DBSCAN-SWA
MSYPLPPPELPPIVETLPSQSVSQYVTDIGQEVSTLNQNQLSPMSKFSQVGEEIKVSVKNTFLGEEFRETVLYKFPQITSNFDHTQKISPIHTTSANLGPPIEIEISSAPRISTLESQINSGRKRIFSSISFSDFSEYALSEKEPENNQLTNSFSLNSRKILERFNHTKQLIPSKFEIGQTIRENNTPKLPNLPQDEQPIRETETPDSEENKKETQFPTTKPESQTQDSENKTEDRQPLEIPLPADVVEVTADRQEYNEQRRLISAVGKVTVRFSQGVISADKVQVNLTTRQLLAIGNAVFTKAEQVLLGERMEYNFTLDKGLIEKASGIIFVGDAEQSTSKSLPTTEGVGALEAISLSDRIAATQPPTKVKATEGTKLRFKAKLKAPKQSGIVNRLRFEADRLNLLGAGTWEAINLRLTNDPFSPPEVELRSDRAILKPLSPFQDELITKKSRLVFDQRFSLPLFRERTVIDRQQRDPLPIQIGYDQDDRGGLFIESTFEPLLPGPLQIKISPQYYLERAFLGDENDYPIDGNVFGLKASVNGTITPTTQVEGRATFLTFEDFPDLEENDFRGSARLRQFFQGYNLTGEYSYRDRLFNGSLGFQTVHSSAGVVLASPVITLGETGVEFSFQSGYQVVNARTDRRELLKDIQPFEPLPNDKNDDDSDSRSRADLGRFQSVVSLRYPLTIWSGKPLTANATEGLRYTSKPVVPFLQMVLGLTGATSFYSNDEDQSFVRGSLGFTGQFGHFSRDFFDYTGFNLTYSQTGLSGQSPFFFDRVEDTNVLLFGLVQQIYQGFRVGYQSGINLENGDILDDRITLEYSRRTYGVVLVFSPRRQTGTFSLRISDFNWEGGTTPFSGEDVRPVGGGVVR
>NC_008312|4838317:4949144|4876980_4880268_-|WP_011612661.1|DBSCAN-SWA
MKFSITEISTTIEQLRKLTQLDIQNKWRSCQEDIPITAVKNLDTWQLATTNEKKQIAWEKGKQILWLGQKLIIPPNLNGYLLTDLSLRLGLVWWAEYVEIYVNGKLVQTGDLFDYSSRILLSQKVVVGKTFIIAIKLVSPAHDRGALVKSWFVYENLNNYQLDPGFMADRLEILLEYLTKFESKIDLKLERIKKSISLIDLQAVGKKEKFERSLLNLHSEITKISESYINSLKLKLLGHAHLDLAWLWDVEETWEAAQRTFTSVLNLQQDFPELIFCHSTPALYEWIEQNRPDLFNKIKRQIELGKWEVTAGLWVEPELNTVGGESIIRQVLYGQRYVWEKFGKFSSVAWLPDTFGFCWQLPQILQGGNIKYFATQKLRWNDLTEFPFEIFWWEAPDKSRIFSFMLPPIGENIEPVKMAKYAYEWQLKTGEKNVFWLPGVGDHGGGPTRDMLEISRRWQKSGFFPVLEFSTAENFFAELVEKNSGIFPVWQDELYLEFHRGCYTTHADQKRRNRRCENLLYQAELFAVFASIMTGAFYRKNDLEMAWKLVLFNQFHDILPGSAIPEAYVNVNQNWSEAERLGKEILAEAMGKVAADVNVSPPFPLDTFADGMIYPIIVFNSLNWQRSELVSVPGKKNIEGAGNREKGEVFELTPNSQHLTFLQGREDDWQVYDDAGQILTSQISDNSLLFLASDIPGVGYRLFWLCSRFSDLNKKSYIGKYIAHHTGTIAKKIENVNTVSLEIEKWVLENNLLRVKVEATTGNLESIFDKINQREVLRKPEGNKLKVFRDEGQYWDAWNIDPNYQQHPLSSAKLIDIFWIEQGKLKSSLRIIRKIGNSQFCQDYILEIGSQLLKIKNWVNWQEKHTLVKAAFPINIEADFTTYEIPCGAIKRTTKPQTEREKAKWEVPALNWADISKDNYGVSLLNDCKYGYDAKPDELRLTLLRGSTWPDSKADVGIHEFTYAIYPHIGSWENAGTVQRGYELNMPLMVQIMPLIREEKSHGKLPQVYRFLGWEAENLILMMLKRSEDNQSWVFRCYECLGKEVKLNLESDAGLRIKKVVNLLEQDVSEPNVNLENNNYNILAWKIVSFSLDIL
>NC_008312|4838317:4949144|4939730_4939820_+|WP_155994701.1|DBSCAN-SWA
MKLVIEIISSNWRNNYAFKLDAYQTIGIE
>NC_008312|4838317:4949144|4942686_4942866_-|WP_044136859.1|DBSCAN-SWA
MNNDEYREVDYPAVVASIVRNRAFIVIFGSANELENFGIFESGVLNDYWDQDFQATVLG
>NC_008312|4838317:4949144|4910933_4912403_+|WP_011612676.1|DBSCAN-SWA
MTNLQIQQPKSYTSKDWQQGYKSQPQEYNYWIDDIEGEIPEDLNGTFFRNGPGLLDINGQLIAHPFDGDGMVCAISFKNRRAHFQNRFVRTEGYVAEKAAGKILYRGVFGTQKTGGWLANLFDFKLKNIANTGIIYWGDKLLALWEGGQPHRLNPQNLETIGLNDLDGLLQPGQAFSAHPRIDKGKDGKGDVLVNFSVKPGLSSTITIFEFNSQGKLLKRYSNSIPGFAFLHDMVITPNYCIFFQNPVAFNPFPLLLGLRTPGQCLEFLPNNSTQVILIPRDGSKAIKILKTKPCFVFHHANAWEKDGEIYVDSICYESVSQTDLGDNFLEVDFDSMTEGKLWRFKINLSENNVEHKLLESRCCEFPTLNPNNVGKAYRYLFIGAADKPSGNAPLQAILKIDLHTGKRQTFSVAPRGFAGEPLFVPFPNGVNEDDGWLLMLMYDAAEHRSDIVILDARDLNKKPVARLHLKHHIPYGLHGSFTPNYFQE
>NC_008312|4838317:4949144|4925464_4926214_+|WP_011612682.1|DBSCAN-SWA
MNEDKITISHLGVHYRTLEALRNITLKIQAGRLTGIIGPNGAGKSTLLKGMLGLIPVSGGSVIYNNKSLQKQLGRVAYVPQRSQIDWTYPATVWDVVMMGRVHQTGWFCRFSRMSRQIALEALTRVGMDSYRDRPIGQLSGGQQQRVFLARSLAQKADIFCFDEPFVGVDQKTENIIFEIFHELAKAGKVVIVVNHDLGKSITNFDDLILLNKELIAVGNRQIVLQEENLYRAYGGKVGFFSESLKQVA
>NC_008312|4838317:4949144|4863542_4864007_+|WP_011612653.1|DBSCAN-SWA
MKIQVGDQAPEFTLPSQEGTEVSLSDFRGKKNVVLYFYPKDDTPGCKIQACTFRDQYTIFKNVDAEIIGISGDSKQSHKQFSTKYSLPFTLLCDTDNKVRQLYDVPPTLWILPGRATYVIDKEGIIRYICDSTFDFEVHSKEALKALRKLRVTV
>NC_008312|4838317:4949144|4924187_4925303_-|WP_011612681.1|DBSCAN-SWA
MKISRYLFQINLTNNAVRKGFTRNRKQEIYLSGKYTNNLAYLLNISTQDLKNTIWSMLGILLGLWISGCAAPSSNISPESENKLLVVSTSTIIADMTEKIGGDEIEHQGIIKPGADPHIYEPVPTDSVAFEKADLIIYNGYNLEPTLIKLMNAAGIKAQKLAVGEKVKPLQNLGKGELVPDPHVWGDAENGIVMVKGIRDALIELSPEDKEVFMENAAKLVEELGQVDIWIMEQIGTIPEGQRRLVTTHDAFEYYAKAYGLEMTGTLIGMSTEEQPSAQTVKNLVKEIKKSGVPAIFAETTINPKLITTVAQEAGVRLAPRELYSDSIGAPGSEGDSYTKMLVSNTQAIVEALGGEYTAFELQITGTLEKN
>NC_008312|4838317:4949144|4873371_4874109_+|WP_011612659.1|DBSCAN-SWA
MSQKKSALSANNEQSFWFAKENLDNWYAQIMAVQARFEQEYRGEPLELPPEVKAMPIFHDFASGNLTAKIVSPFWEIAKPKKNKKCLDIGCGVSFLIYPWRDWQAFFYGQEISTIARDNLNKRGSLLNYKLFKKVELGPAHQLMYQANEFDLAIATGFSCYYPVDYWELVLEEVKRVLKSECHLVFDVINSEQPLAENWAILETYLGAEVFLEPLEKWEKIIKAKGGKIVKQQSGELFHMYKVRF
>NC_008312|4838317:4949144|4919587_4920166_+|WP_011612679.1|DBSCAN-SWA
MLNLRQRFSWPKIFLSLLSFLLAIFFLLLIAIPTALASLNDDRFDGNIFALYAGNGSLVPAKVKLKDSLKNSRPALLVFFLDDSKDCKQFSAVVSQLQEFYGRAADFIPVNVDAMINTVTDDSTKVAYYYQGFVPQTVLINQQGEVVINEKGQVSFEKIDDVFREVFDLLPRSESAELKRRIVNEINVELRE
>NC_008312|4838317:4949144|4920860_4922648_+|WP_011612680.1|DBSCAN-SWA
MSNSYIYGTGEDDLLYGTGGNDKAYGSSGNDIIEGKGGDDELYGNGGNDTIKGEEGDDTVLGHPGDDSIEGNAGDDKLYGGDGDDLVSGGEGNDMQTGGGGNDTIEGGEGDDKLYGGPDDDLIKGEDGQDKLYGNDGNDAMEGGADDDTVLGHAGDDSIEGNAGDDKLYGGDGDDLVSGGEGNDMQTGGGGNDTIEGGEGDDKLYGGPDDDLIKGEDGQDKLYGNDGNDAMEGGADDDTVLGHAGDDSIEGNAGDDKLYGGDGDDLVSGGEGNDMQTGGGGNDTIEGGEGDDKLYGGPDDDLIKGEDGQDELYGNDGNDAMEGGADDDTVLGHAGDDSIEGNAGDDLLSGDSGDDVVSGGEGEDILYGGAGNDELYGGDDNDTIDDGGGDDILEGNTGNDILRGRGGQDELIGGDGDDLIISYSDAGEPEIAQQTNESKVYPDQPFFEANDTLTGGSGADTFLFRPLMNAKPEIIEKHNMHNMHQDMHNMNLHKQIAGENGSVHDHWVDSIGDDIILDFNRSEGDKIEIKGHTVKVEKIEELDDGSGSIVHLISDQGANGGAHHLDKLGTITVYGDLVTESDLIADIFGDGAGMG

Homologous phage analysis in the prophage region

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_011610086.1|4838317_4839355_-|transposase	IS630 family transposase	NA	NA	NA	NA
WP_011612645.1|4839781_4841212_-	dihydrolipoyl dehydrogenase	A0A2K5B2C5	Erysipelothrix_phage	4.6e-33	27.6
WP_044136852.1|4843237_4843441_+	hypothetical protein	NA	NA	NA	NA
WP_081432550.1|4844297_4844447_+	hypothetical protein	NA	NA	NA	NA
WP_011612646.1|4845807_4846593_-	RNA methyltransferase	NA	NA	NA	NA
WP_011612647.1|4847766_4848852_-	alanine dehydrogenase	NA	NA	NA	NA
WP_011612648.1|4849312_4849498_+	transcriptional regulator	NA	NA	NA	NA
WP_071820760.1|4849528_4849606_+	hypothetical protein	NA	NA	NA	NA
WP_011612649.1|4850498_4851890_+	UDP-N-acetylglucosamine 1-carboxyvinyltransferase	NA	NA	NA	NA
WP_011612650.1|4854322_4855660_-	MFS transporter	D0R099	Streptococcus_phage	1.1e-20	28.5
WP_044137604.1|4857112_4858336_-	glycosyltransferase family 1 protein	NA	NA	NA	NA
WP_011612652.1|4860318_4862109_+	fatty acyl-AMP ligase	A0A1V0SBX8	Catovirus	1.8e-05	21.6
WP_011612653.1|4863542_4864007_+	peroxiredoxin	NA	NA	NA	NA
WP_011612654.1|4864217_4864865_-	ribosome-associated translation inhibitor RaiA	NA	NA	NA	NA
WP_011612655.1|4865768_4866434_+	lipoyl(octanoyl) transferase LipB	NA	NA	NA	NA
WP_011612656.1|4866531_4867038_-	single-stranded DNA-binding protein	NA	NA	NA	NA
WP_011612657.1|4869557_4872089_-	NTP transferase domain-containing protein	G3MA50	Bacillus_virus	2.5e-13	28.6
WP_044137606.1|4873162_4873363_+	hypothetical protein	NA	NA	NA	NA
WP_011612659.1|4873371_4874109_+	class I SAM-dependent methyltransferase	NA	NA	NA	NA
WP_011612660.1|4874833_4875961_-|protease	site-2 protease family protein	NA	NA	NA	NA
WP_011612661.1|4876980_4880268_-	alpha-mannosidase	NA	NA	NA	NA
WP_011612662.1|4882296_4883631_+	hypothetical protein	NA	NA	NA	NA
WP_011612663.1|4883739_4883856_+	photosystem II reaction center protein I	NA	NA	NA	NA
WP_011612664.1|4884646_4887262_+	DUF3769 domain-containing protein	NA	NA	NA	NA
WP_044136854.1|4887964_4888147_-	hypothetical protein	NA	NA	NA	NA
WP_011612665.1|4888423_4888987_+	hypothetical protein	NA	NA	NA	NA
WP_081432469.1|4889679_4889940_-	hypothetical protein	NA	NA	NA	NA
WP_011612666.1|4890615_4891140_+	Chromophore lyase CpcS/CpeS 1	NA	NA	NA	NA
WP_011612667.1|4891994_4892129_+	hypothetical protein	NA	NA	NA	NA
WP_081432551.1|4893090_4893198_-	hypothetical protein	NA	NA	NA	NA
WP_052845813.1|4895023_4895446_-	hypothetical protein	NA	NA	NA	NA
WP_011612669.1|4896942_4897173_-|transposase	transposase	NA	NA	NA	NA
WP_011612670.1|4899214_4901035_+	ATP-binding protein	NA	NA	NA	NA
WP_011612671.1|4901296_4903483_+	hypothetical protein	NA	NA	NA	NA
WP_081432470.1|4904812_4905010_-	DUF4277 domain-containing protein	NA	NA	NA	NA
WP_011612672.1|4905457_4906150_+	hypothetical protein	NA	NA	NA	NA
WP_155994449.1|4906361_4906856_-	hypothetical protein	NA	NA	NA	NA
WP_011612674.1|4907276_4908824_-	HAMP domain-containing histidine kinase	NA	NA	NA	NA
WP_011612675.1|4909004_4910381_+	folate/biopterin family MFS transporter	NA	NA	NA	NA
WP_011612676.1|4910933_4912403_+	carotenoid oxygenase family protein	NA	NA	NA	NA
WP_011612677.1|4913652_4917567_+	WD-40 repeat-containing protein	NA	NA	NA	NA
WP_011612678.1|4917941_4919216_+	hypothetical protein	NA	NA	NA	NA
WP_011612679.1|4919587_4920166_+	thioredoxin family protein	NA	NA	NA	NA
WP_011612680.1|4920860_4922648_+	calcium-binding protein	NA	NA	NA	NA
WP_011612681.1|4924187_4925303_-	manganese ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_011612682.1|4925464_4926214_+	metal ABC transporter ATP-binding protein	A0A2R8FG22	Brazilian_cedratvirus	1.4e-12	27.0
WP_155994450.1|4926404_4926803_-	hypothetical protein	NA	NA	NA	NA
WP_011612684.1|4927312_4927558_-	hypothetical protein	NA	NA	NA	NA
WP_011612685.1|4928194_4929331_-	ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	3.5e-31	39.9
WP_011612686.1|4929943_4931611_+	iron ABC transporter permease	NA	NA	NA	NA
WP_071820761.1|4931977_4932190_-	DUF433 domain-containing protein	NA	NA	NA	NA
WP_011612687.1|4932297_4936287_-	magnesium chelatase subunit H	NA	NA	NA	NA
WP_011612688.1|4937985_4938924_-	glycosyltransferase	A8CG95	Salmonella_phage	1.9e-51	38.8
WP_155994701.1|4939730_4939820_+	hypothetical protein	NA	NA	NA	NA
WP_044136858.1|4941212_4942649_+	lipid-A-disaccharide synthase	NA	NA	NA	NA
WP_044136859.1|4942686_4942866_-	hypothetical protein	NA	NA	NA	NA
WP_011612691.1|4943407_4944664_+	SGNH/GDSL hydrolase family protein	NA	NA	NA	NA
WP_011612692.1|4945575_4946556_-|transposase	Rpn family recombination-promoting nuclease/putative transposase	A0A1B2LRR6	Wolbachia_phage	1.4e-20	35.2
WP_011612693.1|4946699_4947848_-|transposase	Rpn family recombination-promoting nuclease/putative transposase	A0A1B2LRR6	Wolbachia_phage	2.1e-20	35.2
WP_011612694.1|4947995_4949144_-|transposase	Rpn family recombination-promoting nuclease/putative transposase	A0A1B2LRR6	Wolbachia_phage	1.6e-20	35.2

Sequences of DBSCAN-SWA_8

Nucleotide sequences of DBSCAN-SWA_8

>NC_008312|5515787:5611019|DBSCAN-SWA
AATGGTTGAAGCAAAATCCTATAAAGAGACCGTAAACCTGCCCCAGACTAACTTTAATATGAGGGCTAACTCAGTCACCAGGGAACCAGAACTACAAAAGTTTTGGGCACAAGAACAAATCTATGAACGTCTTTCTCAGACCAACCCAGGGGAAATCTTCACCCTACATGATGGCCCACCTTATGCTAATGGCAACCTACACATTGGCCATGCCTTGAATAAAATCCTTAAAGACATTATCAACCGCTACCAAATCCTCCAAGGGCGAAAAGTTCGTTATGTTCCTGGTTGGGACTGCCACGGTTTACCCATAGAATTGAAAGTTATTCAAAATATTAAATCAGCAGAAAGGGCAAAACTCACACCCATAGAATTACGTCGCAAAGCTAGAGACTTTGCTCTCGAAACTATAGACAAACAGCGTGAATCATTCAAACGTTATGGAGTTTGGGGAGACTGGGAACATCCCTACATGACTCTCTCTCCAGAATATGAAGCTGCTCAAATTGGGGTATTTGGTAAAATGGTTTTGAAAGGCTACATTTATCGTGGTCTCAAACCTGTACATTGGAGTCCGAGTTCTAAAACTGCTCTTGCAGAAGCAGAACTGGAATATCCCGAAGGTCACAAGTCTCGGAGTATCTATGCTGCTTTTAAAATCACTAACTTGGCAAAAGCAGTTGAAAAGTCTCTCGAATCTTATCTAGAAAAACTCTGGGTGGCCATCTGGACTACAACACCTTGGACTATTCCTGGGAATTTGGCAGTTAGCGTTAACCCAGACCTTAATTATGCTGTTGTCAAACCTGATGCTGACTATGCAATGGGAAAAGACAAATTATTTATAGTTGCAGCAGAAGCAGTTGAACGTTTATCAGCAACTCTGGGCACAACTTTAACACCTGTAGCGACGGTTAAAGGTGAAGACTTAGAAAACTGCACTTACCAACACCCACTGTTTGACCGGGAAAGTAAAATTGTTATTGGTGGGGACTATGTTACTACTGAGTCAGGTACGGGTTTAGTTCATACTGCTCCCGGTCACGGTCAGGAAGACTATATCGTAGGGCAACGTTATAGTTTATCAATTTTGTCCCCTGTGGATGGCAATGGGAAATTTACTGCTGAAGCCGGAGAGTTTACGGGGTTAAGTGTTTTGGCAGAAGGGAATATTGCTGTTATTGAAGCACTGCAAAATGTTAATTCTCTATTGAAAGAGGAACCCTACGAACATAAATATCCCTATGATTGGCGCACTAAAAAACCTACTATTTTCCGAGCAACTGAACAATGGTTTGCTTCTGTTGAAGGTTTCCGCAGTGAAGCACTTAAGGCGATCGCTGAAGTTAACTGGATACCTGCTCAAGGAGAAAACCGCATTACTCCAATGGTGAACGATCGCTCTGACTGGTGTATTTCTCGACAAAGAAGTTGGGGTGTACCTATTCCTGTATTTTATGACGAAAAGACTGGGGAACCTTTGCTAACTGAGGAAACTGTTGCTCATGTGCAAAAAATTATTGCTGAAAAAGGTTCTGATGCTTGGTGGGAAATGTCGGTGGAGGAACTTTTACCAGAAACCTATCGCCAAGATGCTGAGAAGTACCGCAAAGGAACGGATACCATGGATGTCTGGTTTGACTCTGGTTCATCTTGGGCGGCAGTTGCTCAACAAAGGGAAGGGTTAAGATATCCAGTTGATATATATTTGGAAGGTTCTGACCAACATCGCGGTTGGTTTCAGTCAAGTTTGCTGACTAGTATTGCTACTAATGGTGTGGCACCATATCAAACTGTTTTGACTCACGGTTTTGTACTTGACGAGAATGGTCGGAAGATGAGTAAGTCTCTGGGAAATGTGGTAGACCCGGTAATAGTTATTGAAGGTGGCAAAAATCAAAAACAAGAACCTGCTTATGGTGCAGATATTTTGCGTTTGTGGGTTTCTTCTGTAGATTATTCTTCTGATGTACCCCTGGGTAAGAATATTCTCAAGCAAATAGCAGATATTTATCGCAAAATTAGAAATACGGCGCGGTTTTTGTTGGGAAATATCCATGATTTTGATCCGGCAAAAGATGCTGTTGCTTATGAGGAAATGCCAGAACTAGATCGTTATATGTTGCACCGGATTACAGAGGTGTTTGCTGAAGTCAAAGATGGTTTTGATAAATTTCAGTATTTCCGCTTTTTCCAAACAATTCAAAATTTCTGTGTGGTTGACTTATCTAACTTTTATTTGGATATTGCTAAAGATCGACTTTATATTAGTGCGACTGATGCTTTCAGACGTCGCAGTTGTCAGACAGTCTTAGTTGTCGCTGTAGAAAATTTGGCAAAAGCGATCGCTCCAGTTTTACCCCATATGGCAGAAGATATTTGGCAAAATCTTCCTTATCCGACTCCCTGCAAATCTGTATTTGAGTCTGGATGGGTGAAATTAGAGGAAAAATGGCATAACCCAGAGTTAGTTAAGTTATGGGAAGAGTTACGAAAAACTCGCACTGAAGTTAACAAAGTGTTGGAAAAAGCGCGGGCAGAAAAAGCAATTGGTTCGCCTTTAGAAGCTAAGGTATTGTTGTATGTAAAAGATACTAAATTCCGGGAGCAAATACAAGATTTTAATCCCATTGCTCAAGGAGAAAAAAGTAAGTCTGAATTCTGGGAAGCTAAAATCGAAATTGAACCAGAAAAAACAGAAGATAAAACTACTAATAACCAACAAAAGTTTCCTGATATTTTTTATACTTATAAAAATTTTTTATCAGATTTTTCTAATACTGTGAGTAAATTACTTAGTGGGTATAAAAAAGCTTTAGGAGGGGTGTTTTTGATGATTATATTACTGTTATCAATACAACTAACAGTAACGGTAGTAAAAACAATTGAAAAACTGCCTCTAGTAAATTACATCATGATATTAGTGGGAATTATCTACACAATTCGCTTTGTTACTCATAATTTGTTATTTGCTAAAAGTCGCCAAAGTTGGTTAGATAAAATAAAATTGACTGCTGAAGATATATTAGGTAAAGAGGCTTTATCTACTCAAAAGAAAAATTTGGCAGACAATACAGTTAAACAGTCAGCAACTTTAGTATATCCAGAAGGAGTTTTTGTGCCCCCCCAAAAAGTCGAATTTACCCCAGAACCACAAGTAGTAGAAACAGAAACTTTACCTCAACAACCTAATAATGTTAAAGCCATAATTCCTTCTGGTAATGGGGTTGATGAATTACGTTATCTATTTATTACTTCTCAAGTAGAATTATTAGAATCTCCAGAATGTTTAAGTAATCTCGAATATAAGTCTATATTAGATTCTTTAGGTATAGGAGTAGTCAAAGCAGATGGTGAGAAATGCGAACGCTGTTGGAATTATTCTACTCATGTTGGTGACTTCTCAGAAGATCCCACAATTTGTGAACGTTGTGTTGTTGCTTTAGCAGGAGAATTTTAACTGTCTTGCAAAATTTTGTAGGGGCAAATGGCTATTAGCCTCTACCTATTAGACATCTCCAAAATAGAAAATAAGATAAGATTGTCATGTTCATTTATAATTTTATTTAGGTAGCTATACCAATGAATAAAACTTTAGAGTACATTCATAATTATCCGAAAGAAACAAAAAGAATTATAGGGATTACTTATGAACAGCTAACACAATTAATAGAAAATGCAATTATCAAAGAATCAGAAAATTTCCAGGTAATTGCCGAGAAAGAAATAAGTTTAATTAAACCAGGTGGAGGCAGAAAAAAGACTTTAACTAAAACAGAATAAATATTTTTAACGCTATATTATTTACATCATATACCAACTTTTCAATTATTAGGAATAAATTTTGGAGTTAGTGAATCAACAGCCAATAATATATTCCATTACTGGATAAATATTTTACAAGATTTATTACCAGCTAGTTTATTAGAACAAGTAAAAAAAAAGAAGATGAATGAGAAGGGGTAAAAGAAGCGTTAATGGAATTAGAATTAATAGTAGATAGCTCAGAACAAAGTAGAGAAAGACCAAAAGAATCTGAAAAACCAGAAAAATATTATTCAGGAAAAAAGAAAAATAATACCTTTAAAAATCAAATAATAACGACACCAAAAGGAACAGAAATAGTGGATGTAATTATCGGAGAAAGGGGACCATTAAGTGATATAAATTTATTAAACAAACAACGGGAAAATTTTAAGGATAATCAATATTTTCAAGGGGATAAGGCAGATCAAGGAGCAGAAAGAACAAGTACACCAAAAAAGAAACCAAGAAAAAAAGAAATGCCAGAAGAAATAAAAGAAAAAAATCAACAAAAAGCCCAAAAAAGAATATTCGTAGAACATGTAATTAGATTACTAAAAATATTTGGAATTGCGAGAGAAAGATTTAGATTAAAAGAGAAAAGTTATGAGAAAGTAATAATGGTAGTATGTGGATTAGTGAAATTAAGAATAGGAGCATTAATATTAGTATAAAAAGAAGATAATCAATTAAGAGAATAAAGTGAAAATGGGGGGAAATAAATGTTGAATTAGTAAGAGAAAATATCTCAAAGATTTATGATTGCGTATTTTAGGACCAAAGATGCTTGATATGGCAACTAGGCTAAGATCAAGTCAAGGAAAGGCTTTGTTAATTTTTGGAGATGTCTATTTTATAACGCTCAAAAAAATATCATGGTTTTTTTGTTGGAGGGAGAGCGATGGCCTATTTCATATTTCTGTGGTATAATTGTTATATGTAGGGGGTTTATGGCATTCGCCCGGAGAATGTATTGAGTCAGCAATGGTTGTTGTGTTGGTCCTAGTTTTTGACTATTTTTTTTTCATCTCAGAAGCGATGGCCTATTCCATATTTCTGTGGCATAATTAGACCTCTCCAAAATAAAAATTAAGGTAAAATTGTAGTAGCCAATTATATATACTCTGTTTCCAAATGAATAATGTATTAGAATATATTTATAACCATCCAAAAGAAATAAAAAGAATTATTGGTACTACATATGAACAGCTAATAAAATTAATAGAAAACCCTCAAAAAGTTGAAAAAAAAAGACTGGGGAGCGCCAGCCAAGAAAAAAGGTTAATCAAGGCAGGAGGAGGAAGAAAAAAGTCTTTAAGCAAGACAGAAGAGATAATGTTGACCTTATATTATTTGTATCATGTACCAACATTTCAGGGACTAGGAGCAATATTTGGAGTTAGCTCATCAACAGCAAATAATATTTTTCAGGCTTTGGATAGATATTTTGAGGGAATTATTACCATCTAGTTTACTAGAGGAATTCTCGGGAAAAGAAAACGAATATTTATGGATAAAAGAGGCTTTGACATAAAGAGAATTGATAGTTGATAGTACAGAGCAGGATAGGGAAAAGCAAAAAAAATGATGATAAACAGAAAAAGTATTATTCAGGAAAGCCAAAAAGTAATAAGTTTAAAAATCAGATAGTAATCACAGAAAAGGCAGAAAAAATTGTAGATATAATAGGAGGATAAAGAAGTCCAGAAAGTGATATAAAGTTATTCAAAAAAACCACAAAAAATTTGGGTAGAGAACCAAAATTTCAAAGAGATAAAGGATATCAAGATGGTCAAAAATTAACACGCTAAACAAAAAAAAGAATCCATAAAATGTCAGAAGAAGTAAAAAAATAGAATCAAAAAAAAAAGCTCAAAAAATAATATTTGTAGAACATATAATAAGACTGATAAAGATATTTAGAGTGGCACGAAAAAGATTGAGATTGAAAGAGAGTAACGGGACTTTAGCAAATTTCAAGCCCAAACAAACCCTAAACTCTCTTTATGAGCGGTAAATACGTCGATGTTTTCATCTAACCACTCAACAAAACGATAAGATATTGCGGTACGAAATGCTTCTAAAGTATCAGTAAACGTATTTAATGGTTTGTTAGCCCAACGCCTTCTTATACCTCCTGTTAACTGATGCCAGATAATAAATGTATAAGCACAAAATACTAAAATAAAATGCCTTTTAAGGCTGATTTTATCTCTGACTTGATATTCTCTTAATCCTAACCATCCTTTGGCTTCCCTGTAGAAAACTTCCACCCAATTTCTTTGAGAATAAGTAGAATATATCCACTCAGGAGTTACATATTTGTCTTCTCTATTAGTGATATAATAGTTAATATCAGTGGCCTCAGAAAAACTTTTAGCATTCATAACGATAGCTATAGTTTTTTGACCTGACATCCTAGATATTTCTACTTCTAATGTAGCTACCCAAACTTCTCTAGCATTTTTTGTACTTAGTTGAACTAAGTTGAAAGCTTTCTGAGGTATACTTTCTGCCAGCTTGTCTAATCTAATTTCCTCTTTAATGTCATCTTGTTTTTTAATGATGACTTTTCGATTTTTAGCTAATCCTCCTATATAAGTTAAACTTCTTTTCTCTAGTTGATTTAAGAATGATGTATTGTTACCATAGCCAAATTTCAATTAACACAATTTCTGGTTGGTGTCCTCTGGACAAACATTGATCTACTAGAGACATTGCACTCGTCTGGTTTCTTGACAAATTCTGGGTCTTTTTTTCCTTTTGGAAAAGAATCAGCTTTCTGATACAAAGCTATGTCTAAAGGTAGACTTTTAACTCCATCATAAAGATGAGTTGTCACCACGACTACACCATTATCTGTTTTTCCTATTTCTCCTATATATTGCCGCCCTACTCCTGCAGTAAAATTACCACTTTTTCTGTGGCCTGAATCGTCTATAATTAAAGCAATAGGATCGAGAAGGTTTTGTTTGGCGACGTTCCCACATTACTTGAAGACGACGCTCATTCACAGCATCTACAGACCAATTTGCTCGAACTAGAAAATGCCGTAATTTGTGGTACGTGTGACCTACAGTGTTGTTGGCAATTTGAGACAAGTTTTTTCGATCGCTTTCTCAAGAGTAATCCTCCTATATATTCCCTAAACCCTGTTTTTTGGGCTTTTGTTTTAAAGACATTGTTAAAGCGATCGCACCATCGATGGAAACAAGAGGGCATGGCCACTGAAGTTGTTTCTTTCATCAAACTTTTCCCAGGCCAGTAATTAACGTAAAATACATATCAGGTATACATTATACCCTTTTTTTTACTATTTTTTCACTAAAGTCCCGGTAATTATGAGAAAGTAATTTTAAAAATATGTGGTTTAGTAAGATTAAGAAGAGGAGAATTAATATTATTATAAATCATACATTTTGCTTTTTCTGAAAAAATCAATAAAAAACTAGATAAAAATGGTAAATAACTAACAGTAACTATCTGTAATACTATAAAGCCCGTAAAAAATGACTATCTGGTGGAGCTGGCGATCGCTCCCCAAAAGATAGTTACAGTAAATGCTTGATAATTTTTGGAGATGTCTAATTAAACCCCAACTGACTGTCAGCTATTCAAATACTTATACTCTTACCTTGATTTCTAGGGATATTGCTAACTACTCTCTCTCCTATTTTCCATCGACCATAAAGAAGTTCAAATTGGTATTGATGGGGTTACTCCCATAGCTAACTTCACATATAAAGGCACATTTTTAATTACCATGAAAATCGTCTAAAAGAAATTTACGATCAAAAACATCCAAACTAAGGAATTTGAATAGGAGATGGTTGTTATTCTTGCTACAATAAGTATCTCCATAAAAGGTTCTCAAAGCCTTAAACTGCCGTTCCAAAATCGGTATTTTTTGAGAGGTCTAATAGCTATCATGAGTTTTAGTAATATTAATATATAGCAATCCTAAATAGATTGTGGCAAAATTACATACTGAAAAAGCTTTGAGAAATCAAATATTTGACCATCTGCAAAAAACTTAAATAGCCACTTAACTACTTTAAAAGAACTGCAAAGATGATAAAATTGTCTGATGAAACTTTTAGTTTGCAACCAAATATCTTCAACAGGGTTTTGTTCAGGAGCATTTGGGGCAAATGAGCGTACAATTTATCAACCATTCTTCTTCAGGTAAATCTTGATTAATTAACATCAGATATTCTCGAAATTCTTGAGAGTTATGATAAGTTGCACCGTCCCCAAATATTGCCAATCTTTTTCCTGGTCTTTGCTCTTGTAAATATTTAACAAATTCATTCTTTTTTTCAGTATTTCCATTCTTATATTCTTGCACAATGAATTCCTTAGTTTGATAATAATTGGCTCCATAATAAGTTTGTCTTTCTTTTTCATTTTTTTATCGGAATTTCTATTCTTTTATCTGTTCTTCCCCAAGTATAGCTATATAGATCACCCCATAATAGATGACATTCATCAATCATAAACACTGTAAGATTTTCAGATTCTATTTCTGGTTGCCATTTAGTCAATAATTCCTCTATTTCTTTTTTTTTTGCTTTCACTAATTCATCATTTTTAGCGGGATTTTTTTTTGAGTTTTTTTCCAAGTTATTCCTGCTTCTTTGAGTAAGTTATAATAACTTTGATTAGACTCAAAAACCACATCATATTGCTTCTTTAAATATTTTTGTAAATCTGACAATCTTAGGTAATTTTGTGCCCTCAACCACTCAATTATTTGCTCTTTTTCTTCGGCCTTTAAGTAACCTTGTGTTCCAATATAATTGAAGCTTTAAACTTTCACTTGCCATGAAACAGTGCTTGGTTTTTCCATTCGCTTTCTAAACTGCTGAGTTACATTTAATAATTCTTTGACTTCATGATAGGATTTTCCCGACAAAATCATTTTTACAGCTAAGGCTCTTTTTATTTCTTTTGACTATGCATGTGTGATTGATAAAATCGTCTAGTTCATCTATAATATTCATTACTTTGTATTTTGACTGGAGATGTTATTCTTACTATTATATCTGTTGCGACCTATTTAGGATTGCTATAGTAGTCTAAGTATACCACTACGGATAATTAAGAAGTTATAAGTATTCTCTGACTTAATTTCAGCATTTAGCAATGTCAAACACCTTTGTTTCGACTGTTATACCAATAAGTCCTAGTACTAGTCGTCGGTTAACTAAATCTATTGTAGTTGATAATATCCTCTATAAAAAAGCCTGGACTTTAATTACAGAACCTAAAATAACTTACACTATGCCGGAACACTTTGAGCGACCAGAGACATTTGAGCTAGAGCGTTTTTTCCCAGAACATATAGTTATTTTAAATAAGAATGAGACACTATCTGGCACAATAATTACGAATAATTTTATCAAGAGATGTATTGATAGGTAAATACATTCTAGCTCTTTTTAATGCACTAAAATCATGTTCTTAGTCATTTAAATCAGCAGAGTATTTTGGCAAAAATAGTAATTAGTGACTCCCTACTTCTACTAATTCTCTAATAACGTTTTTTCGTAATTAATGGTGAATTATCCATGCAGCAGTACACTGGGCATTTTTAATGATGGTAATAAATGTTTATCTAACCATTGTTCAAATCCCACGGTATTTAGGGTTCCTTTAAATATAATTGGTGGTATTAAATATTTTTCCTTTTTTCTTCTCCCGGCTACTAAATTTTCTCTTTTACCTCGTTTTACCTCTTGCTCACCATAAATTTTTTCCCTTTTTTTGACCAGGTATAAATACCGTCTTGATTATCTTAAAATCCTGATTCATAAATAAATACAAGGCTTTTAATTCCAAATATTTTGATAAAATTTCGAGGGAAAGCTGATAATATTTTATCCTTTATTCTCTATTTCTTTCTCTATAACGAAGTTTTTTTTCAAGGAAAATTCATTATTTTTAAGGCATAAAATATAGCTGGTTGATTAACTCCAAATTTTTTAGCTCTGTCTGACAAAGAAAATTCATTATTTTTAAGGCATAAAATATAGCTGGTTGATTAACTCAAATTTTTTAGCTCTGTCTGACAATGAGCGACTCTGGATTTGGTTTTACATCTTTTTCTAATTCTTTCCAATCTAATTTTATTTGACTACTTTTTACCTTAGTTGCTGAAACTTTTGGGCGAGATAACTATCTATATATCGAAGCTCTTTCTATCCCAAATGTATGAGCTGCTTTGGTAATCGTACCGCCATTTTCTACAAAATTTATGACTTTTTGCCTGAAGTCTAAACTGTAAGGCATAGTTCAAAATAGTTTCTAGTTGACTTGATTTTATTATATTCAATTTTTGTTTCAATCTTAATTAAAACGACTATAATTAAGGTTAGATATACAAATTTATCACTTTTGGGGGTGGAGTACACCCTTGTTTGGGAGCGCAAATGGCAATGGTGATTAGTAAAGTTTTTGCATCTCATCTGCTAAGAATATTTAAGTGGAAAATCACTCTTTCTATCCAAAGTTTGTTCGTTGTCCCATTAAGAAAATTAGAGATGATTATCAAATTCAAATTCAAACTAAAACTAAGAATTAAATATGCCATTCTAGTGCTGCCGTAAGTATGAATATATTTATGAACTATACACAAATGCTAATAATTTACTATTTGACGATAATGTAGTAAATATTACAGAAAATATTTACCTGATAAGTAACATAGAGTTTGATATTACTGTTAATTTTAATGGGATAAAGTAATAATAATAAGAGAACTAATTTATAATATTCAGTTAGAGTTAGTTGATCAATTCCCGACCTTAATGCTATTTCTAAATAGTCGTGCTTTGCTAGCCGAAGCCTCGAACACAAGTATTCTTTAATTTTGACCAAAAATTTTCGCGGTTGGTTAAATTCAGGAGAATAGGTCAGATATATTAACCATCTTTATTTAGTGCTTCTTCGAGCATAGTTCTTCTAGACGGGAACTTGATAATCTGGTAAGTTTTCCATTACTGAATACGCACCAAGCCATAAGCTAGGTAATAAAACTTGTTCAATAAAAACTTGGAAAACATTTTTACTCCTACCACCATTAATGGTCATAATTCCAGCAAAACCAGACAAAAAAATTGTACTAATTAATGTTAAGTTTGTTCCCCTTTTAGAGACGAGTATCATAAAACCTATCTCCTTTGAGAGAAAAACATAGATTTTTTCATGGCTAAATTTATGATAGTTTCATCTCTCAAAGACTAGGTTGTCCGGCTATCAATATTTAATGTTTTCCCCATAATCAAGTCTTTTTTTCTAGATTTTTTTTTAGTTATAGCTTGATATGTACAAAAAGTTTTTTTCTGTCAAGTTAAATTTTTGAATATCAACACACAGAATAGAATGACTTACAGTTATTCCTGTTTCGCTTTCTATTTAAAAATATAAGTCTTTGAAAGTAGCATCTGGTTTTTCCTGAACTAACTTTTCTAAATTTTTTATTCAAAACCTTTTAAGTTAATTTATGAGCCTAACTAGGAGGATAAGATTTTGCTTGTATATGACCATTATCAATATATCTCTTGATTGATGAGTTTTTGTACAAAACTCTTCGCCACTTAAAGACCAATAGCTAGTTGAAAAATTGAACTTATTTGAACAAAAAAAGTTTCAATAATTTTTTCTCAGGTCATGATAATAAGTCTTCATAGTAGTGGATAAATTAGATGTTTAATAATCAATGTGAAGTGATGCTATGAACTTTAGTGATCGTCTATAATAAATTATTTTATTGATTCACTCATTACTATTATTGTACCTCAGTATCCTCAAAAGTACTGTAATTCTCACTCTTACATCTCCAAAAATTATCAAGCATTTACTGTAACTATCTTTTGGGGAGCGATCGCCAGCTCCACCAGATAGTCATTTTTTACGGGCTTTATAGTATTACAGATAGTTACTGTTAGTTATTTACCATTTTTATCTAGTTTTTTATTGATTTTTTCAGAGAAAGCAAAATGTATGATTTATAATAATATTAATTCTCCTCTTCTTAATATTACTAAACCACATATTTTTAAAATTACTTTCTCATAATTACTCTCTTTCAATCTCAATCTTTTTCGTGCCACTCTAAATATCTTTATCAGTCTTATTATATGTTCTACAAATATTATTTTTGAGCTTTTTTTTGATTGTCTTTCTTTACTTCTTCTGACATTTTATGGCTTCTTTTTTTTGTTTAGCGTGTTAATTTTTGACCATCTTGATATCCTTTATCTCTTTGAAATCTTGGTTCTCTACCCAAATTTTTTGTGGTTTTTTTGAATAACTTTATATCACTTTTTGGACTTCTTTATCCTCCTATTATATCTACAATTTTTTCTGCCTTTTCTGTGATTACTATCTGATTTTTAAACTTATTACTTTTTGGCTTTCCTGAATAATACTTTTTCTGTTTATCATCATTTTTTTTGCTTTTCCCTATCCTGCTCTGTACTATCAACTATCAATTCTCTTTATGTCAAAGCCTCTTTTATCCATAAATATTCGTTTTCTTTTCCCGAGAATTCCTCTAGTAAACTAGATGGTAATAATTCCCTCAAAATATCTATCCAAAGCCTGAAAAATATTATTTGCTGTTGATGAGCTAACTCCAAATATTGCTCCTAGTCCCTGAAATGTTGGTACATGATACAAATAATATAAGGTCAACATTATCTCTTCTGTCTTGCTTAAAGACTTTTTTCTTCCTCCTCCTGCCTTGATTAACCTTTTTTCTTGGCTGGCGCTCCCCTATCTTTTTTTTTCAACTTTTTGAGGGTTTTCTATTAATTTTATTAGCTGTTCATCTGTAATACCAATAATTCTTTTTGTTTCTTTTGGGTGGTTATAAATATATTCTAATACATTATTCATTTGGAAACAGGGTATATATAATTGGCCACTACAATTTTACCTTAATTTTTATTTTGGAGAGGTCTAAAGCACTCACAAATAAAGACATTAGCCTTTCGGGGTTTAAAAACTTGTCTTTTTTTCGAGCTATCAAGCTCACATATACTAAAACTCTGGGAAAACTTAAGTAGAAAAATCAACAGTTAATTGTTACTTCTACTTTCTCTGAACAACCCCTTACTGAAAAAAAACTTAGATAGCAAGTCTTAAACAACAAATACATGCTAAAGTTAACCTGCAACCACAAAAGGTTGTTAAATATTAATGTCTAGACAAGTCTTATAAAAAAATAAAATTTATTGCCTATAACTATAGTGCTATAGTAAAAGTAAATATTACTAATTATAATTATTATGACTTATATTGGAACTAGAGAAGCTGCTTTTTTATTAGGTATCTGTTGTCAACGAGTCAGAGCTCTACTTTCTCAAGGTAGAATAAAAGATGCTTATAAAGATAACGGACTTTGGCAAATTCCTCTATACGGAAAAATGCCTATTGTCATACCAGGTAAGAGAGGTCCTAAAGGTGTTTGGTGTCATCACAAACGGAAGCATCCAACTAAAATTCATGTCAATCAACATTTTATTAAAGTGAATGCTAAAAGAATTAATGAAGATCCTCTAATGACTCCTGACCAATTAATACCAGTAATTACCTTGAAGCAGACAAATCGTAACGATATGGGTTATCAGATGGTTCTTGATGGTCAGTGTCGTATAGTTTATAAACCCTATGAACCCTTACCTTGTGGCGCACATTTGTGGATTGAAACTTACAAGCCAGTGCAGTTTGTGGATACTCGTTTTAAACCTAGGAGTGCTAGGCGACCGTACAAAGATATCTGTTGATATGCAAATATTAATTCCAGCATTATTTCTAACTGTCTGCTTTGGTCTAGGCTCTCTTCCTCTAACTAATTTAATAGTTAAAAATCTGGGAAATATTAACCTAACAAAAGTTGGTACAGGTAACCCTAGCGTGGCAGCCGCATTTGTTCACGCACAAAAATCTGTGGCAATATTTGCAGTCTTAGCAGAAATTATTAGAGGTATTACTCCTGTTTTAGTAGCAAAATTATTATTTCCAGAAATTTCTACTTGGCAATTAGTAGGATTAATATTTTTAGTGGCAGGTAGATATTTCATTGCTCAAGGTGGCGGTGTTACTAATGCTAGTTGGGGCGTTTTGATTTATTCTCCCGTTGTTGCATTGGCTTCGGGAATTACAGGTTTTTCAATATTAGTCATAGGTAAACAAGTCTTTCCTCACAAGAATCAAAATATTCAAAAATGGTCGGCTCGTTTGGGATGTCTCAGTAGTTTTTTCTGGGTTTTATTCTTTCGCACCTCAGCATCTTTATTAGAATTATTCGCAGCAGCAGGATTAGCAATTTTCTTAGTAGTAATAAACTTTTTCCAGAGTGATGATATGGCTTTACAAAAACGACCTATATTTTCTCTCAATAGTCAACTTGATGCTAAAATTTGTGGAGAAAAAGCAGCTAGATTAGCTTTACTAAAAAAATCCGGTTTTAATGTTCCTGAAGGTTTTGTTTTACCTGCAATTGAAAATGGAAATAGGAAATTGGTTGTGGAGAGTGAAATGACAAAAGCTATTCCTAATACTCGACTCCCAACTGGCTTTTTCTCAGTAGGTAAAATTTTAGATAAGTTAGATAAAATGTCTGGGAGTTTTCCATTAATTGTTCGTTCTTCAGCAGTAGGGGAAGATAGTGATAATAGTTCTGCTGCCGGACAATATGAAACTATTTATCCTGTGACAAATGAAACGGAATTATTAGAGGCAATTAATATTTGTCGTCAGTCTTATTGGTTACCAGAAGCTATTGCTTATCGGCAACAAAGAGAAATTCCTGATGGGGAAATGGCGGTTTTGATTCAGCCTTATATTATGAGTCAAGTTGCTGGAGTAATGTTTACTAGAAATCCTGTGGATGGTAGTGCAAAAATAATTATTGAAGCTTTGCCTGGAGGTGCAGCAAAAGTTGTGGGTGGGCGGTTGACTCCCCTACATTTAGAAATTGATAAAAATAGATTTCACGAAATTAAAAATTCCACAGTCAAAGGTAAAAGTTATCCTTCTATTAATGAATATGCTGATTTTTTTACTAAATTAGAAAATCAGGATATTTTACTTCCAGAAATTATTCAAGAATTGGTAAGTAAAGCAGAAGCTATTGAAGAATTTTTTCATGGTTTGCCTCAAGATATTGAATGGTGTTGGGATGGGGAAAAAATTTGGATTTTGCAAAGTCGCCCAATTACTAATCTGAGACCTATTTGGACTCGAACTATTGCAGCAGAAGTAATTCCAGGGGCTATTCATCCTTTAACTTGGTCGATAAATCGTCCTCTGACTTGTGGGGTTTGGGGAGAAATTTTTACTATTGTTTTAGGGGAAAAGGTAGCAAAGTTAGACTTTACTGAAACGGCAACTTTACTGGGTTCTCATGCTTATTTTAATGCTACTTTGTTAGGGGAAATTTTTAGAATGATGGGATTGCCGGAACAGGGTTTAGAGTTTTTATTACGAGGGCAAAAAATGGGAAAACCTCCTTTAGAAAAAGTCTGGTCTGCTTTGCCTGGTTTATGGCGTTTGATTCAAAAAGAAATGGCAATTGATGACGAGTTTGAGCGTGACTATCATCAAATTTTTGTTCCCGCACTACAAAGTTTGGAAAATAATTTTCAACATAATTTTCCGGAAAATTCGTCTCAGTGTTTATCAGAATTATTGGTTCAAGTAGAAAGAATTCAGGAATGGTTAAAACCGATTACTTTTTACAATATTTTGGGTCCTATAGGTTTAGGGATTAGGCGATCGATCTTCGGTGTTTCTGAAGAATGGTTACCTACTGATACTGCTCCTGAAATTGTTTCAATTCGAGAATTACAAAGGTTGGCAGTTAAGTTGAAAATGGCAACTAAATCTGATGTAGAAATAGAGGCAGAATTTCAGCAAAATCAGGAATTACAATTGGAGTTTCAGCGATGGTTGAAAAGTTATGGTTACTTGAGCGAGGTTGGTACGGATATTGCTGTGGTAACTTGGGGAGAAAAGCCGGATAATTTCCGCGATTTATTATTTGCAATGGCTCGGAAAGGTGAGAGAGAAAAAGATAATTTTTCGGTAAGGTCTTTAAATTTTTGGCAGAGTTGGCGACTGGGAAAATGTAGAAAACGTGCTAGAACTAAGGGTAAAATTGCTGAAGTTTATGGAAAACTTTTGGCTGATTTACGACGGACGTTTTTGGCAATGGAAAATTATGGATTAGAAGCAGGAATTTTTGAGCAAAAAGGAGATATTTTTTATTTGGAATTTGCCGAAGTTAGGGAATGGATTTTATCTACAGTGGGTTTGGTCTCAGAAGGAAACCTAAAAAAGTTTAATACAGAAGCTCCTGTAGGTTTGGTCTCAGAACAAAATCCAACAAATAGTTTAGGAGTCTCGGAACAAAACAGAAAAGGATTTAATGTAGTTTCTCCCCACACTTCTCAAATTCCCCAAACTTCGCACAAGCAAGTGATTATCAAGAATGAAATAAGTTATCTCAATCTCAGAGAACTTATCCGTCAAAGGCAGGAACAGTTGGAAAAAGATGGCGATCGCCTAGTTCCCTCTGTAGTTTATGGGAATGTATTACCCCAAGAAAGTCAGGAAACTTTCTCTAGTGAGGAAAATGTTTCTTTTTTACAAGGGATACCAGGGAGTGTTGGGTGTGTGGAAGGTTATATCAAGGTTTGTCGGAGTTTAGAAGTAAATCTTACTGAGGATGAAGGTTTAATTATAGTTGTGCCTTATACGGATGCTGGTTGGGCGCCTTTGTTATTGAAGGCAAAGGGTATTATTGCTGAAGTGGGGGGGCAGTTATCCCACGGAGCTATTATTGCGCGGGAGTATGGCATTCCGGCAGTAATGAATATTTCTGGAGCGATGACTCGTTTACAGGATGGGCAGAAAGTTAGGGTAGATGGGTTTCGGGGTACTGTGGAATTGTTATTTTAAGTATTTGGATACTCACAAGGAAAAGATGCAGTAAATAATTTTAAAAAAACTCCTAAAATTAATTCAACCAATTTTAGAGAAAAATCCAGATTTGGGAAAAGATGATCAAAAATTCCCGATTGGTGTCAGAATGAAAGTCTTTTTGGATTAGACATCTCCAAAAATCAACAAAGCCTTTCCTTGACTTGATCTTAGCCTAGTTGCCATATCAAGCATCTTTGGTCCTAAAATACGCAATCATAAATCTTTGAGATATTTTCTCTTACTAATTCAACATTTATTTCCCCCCATTTTCACTTTATTCTCTTAATTTATTATCTTCTTTTTATACTAATATTAATGCTCCTATTCTTAATTTCACTAATCCACATACTACCATTATTACTTTCTCATAACTTTTCTCTTTTAATCTAAATCTTTCTCTCGCAATTCCAAATATTTTTAGTAATCTAATTACATGTTCTACGAATATTCTTTTTTGGACTTTTTGTTGATTTTTTTCTTTTATTTCTTCTGGCATTTCTTTTTTTCTTGGTTTCTTTTTTGGTGTACTTGTTCTTTCTGCTCCTTGATCTGCCTTATCCCCTTGAAAATATTGATTATCCTTAAAATTTTCCCGTTGTTTGTTTAATAAATTTATATCACTTAATGGTCCCCTTTCTCCGATAATTACATCCACTATTTCTGTTCCTTTTGGTGTCGTTATTATTTGATTTTTAAAGGTATTATTTTTCTTTTTTCCTGAATAATATTTTTCTGGTTTTTCAGATTCTTTTGGTCTTTCTCTACTTTGTTCTGAGCTATCTACTATTAATTCTAATTCCATTAACGCTTCTTTTACCCCTTCTCATTCATCTTCTTTTTTTTTACTTGTTCTAATAAACTAGCTGGTAATAAATCTGGTAAAATATTTATCCAGTAATGAAATATATTATTGGCTGTTGATTCACTAACTCCAAAATTTATTCCTAATAATTGAAAAGTTGGTATATGATGTAAATAATATAGCGTTAAAAATACTTATTCTGTTTTAGTTAAAGTCTTTTTTCTGCCTCCACCTGGTTTAATTAAACTTATTTCTTTCTCGGCAATTACCTGGAAATTTTCTGATTCTTTGATAATTGCATTTTCTATTAATTGTGTTAGCTGTTCATAAGTAATCCCTATAATTCTTTTTGTTTCTTTCGGATAATTATGAATGTACTCTAAAGTTTTATTCATTGGTATAGCTACCTAAATAAAATTATAAATGAACATGACAATCTTATCTTATTTTCTATTTTGGAGATGTCTATTGAAAACTATTTCGAGGCAAAAATTATCTATAAAGGTGTAAAAAAATTGGAAAATAGCAATTGCAGTTTTTTTATAGATGTTTATATGGCTTATTAGAGCTATTAACTGAAGAATTTTTTTTTGAATTTACTCATCTTAACAGTATTTGTTTCGGGAAATTTTGAGAATTATTGGCAGAAAAATTTCCTGATTAAGTTAACATAATTCAGCTAGATAACAGTGGTTTGCATAAAGTATTAATATTAAATATTACTGAGAATATAGTGTGACTATTTTAAGCTGCTTATAAACCACAATTTAATCCAATAGAAAAGTTATGATAATACATCAAGGAAGATTTTAAGTGGATTAATTTTGGCAGTATAGAGGAATTACAAAATGCTCGTTCCTAAAAGTTTAAGTAAGTTAACCCAAAAAGTAATAGCTCGAATCACTGGCTGGGAATTTATAGAAAGGTTATGGCAATACATCAAGGAAGATGTTAAGTAGATTAATTTTGGCAGTATAGAGGAATTACAAAATGCTCGTTCCTAAGAGTTTAAGTAAGTTAACCTAAAAAGTAATAGACATCTCCAAAATAGAAAATAAGGTAAAATTATCAAAACCATTTATGTATACAGTCTCCCAAATAAATCCAACTTTAGGATATATTTATAATTATCCAAAAGAAACAAAAAGAATTATTGGTATTACTTATAAACAGCTAATACAATTAATAGAAAATGCCCCTAAGAATAGAATAAAAAAAGTCGGCAATCGCCAAAATATAAAAAAGATTAATTAAAGCAGGTGGAGTCATAAAAAAGAATTTAACAAGGGAAGAAGAAATAATTTTCACATGATTTTATTTACATCAAATACTAACGGGACTTTAGCAAATTTCAAGCCCAAACAAACCCTAAACTCTCTTTATGAGCGGTAAATACGTCGATGTTTTCATCTAACCACTCAACAAAACGATAAGATATTGCGGTACGAAATGCTTCTAAAGTATCAGTAAACGTATTTAATGGTTTGTTAGCCCAACGCCTTCTTATACCTCCTGTTAACTGATGCCAGATAATAAATGTATAAGCACAAAATACTAAAATAAAATGCCTTTTAAGGCTGATTTTATCTCTGACTTGATATTCTCTTAATCCTAACCATCCTTTGGCTTCCCTGTAGAAAACTTCCACCCAATTTCTTTGAGAATAAGTAGAATATATCCACTCAGGAGTTACATATTTGTCTTCTCTATTAGTGATATAATAGTTAATATCAGTGGCCTCAGAAAAACTTTTAGCATTCATAACGATAGCTATAGTTTTTTGACCTGACATCCTAGATATTTCTACTTCTAATGTAGCTACCCAAACTTCTCTAGCATTTTTTGTACTTAGTTGAACTAAGTTGAAAGCTTTCTGAGGTATACTTTCTGCCAGCTTGTCTAATCTAATTTCCTCTTTAATGTCATCTTGTTTTTTAATGATGACTTTTCGATTTTTAGCTAATCCTCCTATATAAGTTAAACTTCTTTTCTCTAGTTGATTTAAGAATGATGTATTGTTACCATAGCCAAATTTCAATTAACACAATTTCTGGTTGGTGTCCTCTGGACAAACATTGATCTACTAGAGACATTGCACTCGTCTGGTTTCTTGACAAATTCTGGGTCTTTTTTTCCTTTTGGAAAAGAATCAGCTTTCTGATACAAAGCTATGTCTAAAGGTAGACTTTTAACTCCATCATAAAGATGAGTTGTCACCACGACTACACCATTATCTGTTTTTCCTATTTCTCCTATATATTGCCGCCCTACTCCTGCAGTAAAATTACCACTTTTTCTGTGGCCTGAATCGTCTATAATTAAAGCAATAGGATCGAGAAGGTTTTGTTTGGCGACGTTCCCACATTACTTGAAGACGACGCTCATTCACAGCATCTACAGACCAATTTGCTCGAACTAGAAAATGCCGTAATTTGTGGTACGTGTGACCTACAGTGTTGTTGGCAATTTGAGACAAGTTTTTTCGATCGCTTTCTCAAGAGTAATCCTCCTATATATTCCCTAAACCCTGTTTTTTGGGCTTTTGTTTTAAAGACATTGTTAAAGCGATCGCACCATCGATGGAAACAAGAGGGCATGGCCACTGAAGTTGTTTCTTTCATCAAACTTTTCCCAGGCCAGTAATTAACGTAAAATACATATCAGGTATACATTATACCCTTTTTTTTACTATTTTTTCACTAAAGTCCCGCTAAGTTTTCAAACATTAGGAATTAACTTTGATATCAGTGAATCAAGTGCTAATAATATTTTTCATTACTGGATAGATATTCTCAGATAATTACTGCCAGCAAGTTTATTAGAAAAAGTAAAAAAAGAAAATGAATTGGAATGGGTAAAGGAGATATTAACAGAATTCTAATTAATTTTAGATATTACAGAACAAGGTAGAAGAAGACCAAGTGAATATAAAAACCAAGAAAAATATCAAATATGAAAAAAGAAAAATTATACTTTTAAAAATTAAATAATAACGATACCAAAAGGAACAGAAATAGTGGATGTAATAGTAGGAGAAAAAGGTCCAGTAAGTGATGTAAAAATATTAATAAAACAACCGAATAAACTTGATAAAAAACAAAAATTTTAAGGAGATAAAGCTGATGAAGGAGTAGAAATAAGTACCTAGACAAAATTAATTGTATATTCTGTACCAAAGTTTTTGAGGATTTTTTTCACTGCATTTACTTGCATTAGAATAACTCTCATAAGCTTCGCTTTCTAACCATTTATATTTGATAAAACGCCACCAAATTTCTATAATATTTAACTGTGTAGAATAAGTTGGTAAAAAGAATATTTATAAACCTTTTTCTCTCCATTCATCTTCTTGATCCCAGAAAAGATTGTTTTGATGTATTGAAGAGTTATCCATTACTAAAACTGTCTTTTTATTTACTTTTTCACAAAATTTGTCTATGTAAGCTATCACAACATCACTATTTATACTACAGCTAAAAGTGTAAGCCTCTAGCTCATTAGATTTACTAAGAAATCCTAAAACATTTAGTCTTTTACTTTGTTGACTTTTGATTTCTATTTTTTGATTTGTTTCTTGCCAAGCATAAGGAATATAGGGAATTAAACAAAACCCACTTTCATCTAAATACCTAATTTCTATTTCTCCTTTTTCCTCTTGCCTTTTCAATTGTTCTAGCTTCTCAACTTTCCTCTCGTAAAAACCGGGGATAGGTTCACCGCCTATTCTTCTTTTTATTCTGTACCATCCCATTTTTCCTAATTTTATTACTCTTTTAATTGTTTTTTTACTGACTTTAATTTTCCATTGCTTTGGGATTTTTTCTGGGACTTTTTCAAGACTTTTAGGAGTTGCTTTTACCCAGTCCTTTATCTGTTGTTCTTGTACTGAATTAAAGGTCTTTTTTCTGCCACGACCAGGCTGGTTATATAGTCCTACCAAGTTTGATGATTCCCATGAATTCAACCAATTATAAATTGTGTTACGACTTACTTTAAATATTTTCATCAATTCCAATATCTTATATCCCTTCCAGCTTAGTTGAATACAATGTGCTCTCTGTCTTACTTGATAATATTTGCTCTGGAAGTGTAAATTCTGTCTAACATTTTCGACGTTTCTCTTGTTAACCCCTTAATATGTCTCATTCTCACTTTATGTTTCCTGATTGTTTTCCAGGGAGATTAGCAAACTGGCTGCCACTTCGTCCTCTGGCTGGGGGTGCTGTGCCATCGGCTGAAAGCCAAGTACGAAGATAATGGCACTTGTGCGATCGCTAACTTTTTCCCTCTGGACATTATTATCTAATACTTTTGTTAAAAATATACAATTAATTTTGTCTAATCACTTAACTACTACACAAAAAAAGAAATCAAGAAAAAAAGAAATTCCACCAGAAATCAAAGAAGAAAATCAAGAAAAAGCCAAAAAAAGAATATTTTTAGAACATGTAATAAGATTAATTAAAATATTTATACTTCCTCGAGAAAGATTCAGATTAAAAGATAATAATTATTAAAAAGTACTTTTAACAATATGTGGTTTAGTGCGACTAATAATTAGCTAATTTATATTAGTAAAAATCATCAAAAACTGAGATAAAAATAATAAATTAAAGTCTAATAAATATTTGAATTAGTAACACGAAGTATCTCTGATACCCATAAAACTGTACAAATTACTATCTTCAAGGTGAGCTAACGCTCCACTAAAAATAGTTAGTATAAGCGTTTGAGTATTTTTGGAGATATCTAATAGCTCGAATCACTGGCTGGGAATTTATAGAAAGATTATGGCAATACATCAAGGAAGATTTTAAGTGGATTAATTTTGGCAGTATAGAGGAATTACAAAATGCTCGTTCCTAAAAGTTTAAGCAAATTAACCTAAAAAGTAATAGCTCGAATCACTGACTGGGAATTTATAGAAAGGTTATGGCAATATATCAAGGAAGATTTTAAGCGGATTAATTTTGGCAGTATAGAGGAATTACAAAATGCTCGTTCCTAAAAGTTTAAACAAGTTAACCCAAAAAGTAATAGCTCGAATCACTGGCTGGAAATTTATTGTTAATGCTTTATCAATAGCCAATATTTAGGTAGCGATCGCCTTTCAGTATTAGACTTCTCCGAAAATAGTCAAATCAATACTATAACTATCTTAATTGGAGCGATCGCTATTTCAAGAAGATAGTTGATTTTTACAGTCTCATAGGTATTAGAGATAGTTAGTATTAATATATAGCCCTAATTATAGTATTTTCAGCCAAGAATTTTTTCAGAAATTATTGGCAAATTTATTAAGACAAAATAACCGTCTCTATTCCCAGTCTTACAAGTCCACAAATAGTCATTATTATTTGCGTATATTTATCAGAATTTAGCCTGAATCTTTCCTGGGCTACTCGAAATATTTTGAGTAATCTAATTATATGTTCTACAAAAATTCTTTCAGATGCCAGCTCTTTATTTTGAGACTTTTCCTTACTGGTTAATTCTTGAATATGGGGCTTTTTTTTAGGCGTTTTTATTGCTGGTTCTCCCACATAAGCTTTGTCCCTGGTAAATTTTTGTTCTTGATGGAATTTTTCTTGGATTTCACGAAAAAAATTTATATCACTTATTTGGCCTATTTTTCCAGCTTCGATATCAACAATATCTTTACCATTGGTTAACACAATCATCTAACTTTTTCTTGTATGACTTTTTTTCTTTCCTGAGTAATATTCTTTTTGTTCTTCAGATTTTTCTGGCCTTTCTATACCGTGTTCATAGCTATCTATGATTAACTCACACTCTGTTAAAATTTCCTTAATAATTTCTTTGTCACTTGAGTTTTTTTTTACCTGTTCTAGGAGACTTGATAGTAACAACTCCCCAATTATTGGAAACTAATAATTAAAGATATCATTGGCAGTAGTTTCACTGACTCCAAATTGAATTCCTAATAGTTGAAAAGTTGTCAAATGTATTAAATAAGTTAAGGTTAAAATGATTTGTTCACAAGAGTGATAATTTAGGTGATCTACCACCACCAGAAGCGATTATTCTAACTTTTTTAGCTGTGGCTATTTCTTGCTTCTTCGATACAAAGTTTTTCTGCTTGTTTTAATAACTTTTCTACCTATTCATACTTGATACCTAATAAACGTTCTGATTCTTGTGGAAGATGTCTGAATATACTCAAGTATATTAGTCATAATTTACCTACAAAAATTTCCATTTTTTATTACTCTATCAAAATTTATTGATTTTTCGGAGATGTCTATTTAATATTGAAAAATTGATCGCTCCTAATCATTTGTAAGATTCTTTTTAAAAATGGTATGATTTAGATTTATCATGATTAGTTTATATCAAAAATAAAAAATTAATTTCATTTTCATTAGACCTCTCCAAAATAAAAATTAAGGTAAAATTGTAGTAGCAAATTATATATAGTCTGTAGACCTCTCCAAAATAAAAATTAAGGTAAAATTGTAGTAGCAAATTATATATAGTCTGTTTCCAAATTAATAATGTATTAGAATATATTTATAACCATCTAAAATAAATAAAAAGAATTATTGGTATTACAGATGAACAGCTAATAAAATTAATATAAAACCCTCAAAAAGTTGAAAAAAAAAGACAGGCGATAGCCAGCAAAAAAAAGGTTAATCAAGGTAGGAGGAGGAAGAAAAAAGTCTTTCAGCAAGACAGAAGAGATAATATTGACCTTATATTATTTGCATCATGTACCAAAATTTCAGCGAGTAGAAGCAATATTTGGAGTTAGCTCATCAACAGCAAATAATATTTTTCAGGCTTTGGATAGATATTTTGAGGTAATTATTACCATCTAGTTTACTAGAGAAATTCTCGGGAAAAGAAAACGAATCTTTATGGATAAAAGAGGCTTTGCCAGAAATAGAATTGATAGTTGATAGTACAGAGCAAGATAAAGAAATACCAAAAAATAATGATAAATAGAAAAAGTATTATTCAGGAAAGCCAAAAAGTAATAAATTTAAAAATCAAATAGTAATCACAGAAAAGGCAGAAAAAATAGTAGATGTAATAGTAGGATAAAAAAGTCCATAAAGTGATATAAAGTTATTCAACAAAACCACAAAAAAGTTGGATATATAAGCAAGATTTTCAAGAGATAGGGGGTATCAAAATGGTCAAAAATTAACACGCCAAACAAAAAAAAGAATCCATAAAATGTCGAAAAAAGTAAAGATATAGAATCAAAGAAAAAAGGTTAATCAAGGCAGGAGGAGGAATAAAAAAGTCTTTCAGCAAGACAGAAGAGATAATGTTGACCTTATATTATTTGCATCATGTACCAAAATTTCAGCGACTAGGAGCAATATTTGGAGTTAGCTCATCAACAGCAAATAATATTTTTCAGGCTTTGGATAGATATTTTGAGGTAATTATTACCATCTAGTTTACTAGAGAAATTCTCGGGAAAAGAAAACGAATATTTATGGATAAAAGAGGCTTTGACAGAAATAGAATTGATAGTTGATAGTATAGAGCAGGATAGGGAAAAGCAAAAAAAAATGATGATAAACAGAAAAAGTATTATTCAGGAAAGCCAAAAAGTCATAAGTTTAAAAATTAAATAGTAATCACAGAAAAGGCAGAATAAATTGTAGATATAATAGGAGGATAAAGAGGTCAAAAAAGTGATATAAAGTTATTCAAAAAAACCACAAAAAAATTGAATACATAAGCAAGATTTCAAAGAAATAAGGGGTATCAATATGGTCAAAAATTAACACGTCAAACAAAAAATAAGAAGCTATAAAATGTCTAAAAAAGTCAAGATATAGAATCAAAAAAATCTCAAAAAATAATATTTGTAGAACATATAATAAGACCGATAAAAATATTCATAGTGGCACGATAAAGATTGAGATTTAAAGACAGTAACTATGAAAAAGTAATTTAAAAAATATGTAGTTTATCAAGATTAATAAGAGGATATTTTTTATTATTATAGGTCATAAATTTTGCCCTAAAAAAAACAATAAAAAACTAGACAAAAATGGTAAATAACTAACAGTAACTATCTGTAATACTATAAAGCCTGTAAAAAATGACTATCTGGTGGAGCTAAAGCCTGTAAAAAATGACTATCTGGTGGAGCTGGCGATCGCTCCCCAAAAGATAGTTACAGTAAGTGTTTGATAATTTTTGGAGATGTCTATTTGTTATATGAACCTATGCCACTAATAAAATGCGATTAATCTACATAAGTATAGTGGCAAGCACTACAAAAGCACCAAAACAAGTATAAATACGCCCCCATATTACAACTAGGCGACGATATTTACCTTGATACCAGGCAAAACAACCCTCTTGTTGAAAACGAGGTACAGAAATTTTGATCCCTCGTCCTGGTTTCTTTTTGTCTTTCCAAAGTCGTTTGGGCAGTTGAGGTCTAATCCCTCTTTGATACCTTGCTTGTCTTTGTCGTTGACAATCATATCCTTTATCAGTGGTAATAACTTGGAATCGCTTACGTGGAGGGCCCCGTTTTTAAGTTTTCACACTTAGTACTATCAATTAAGGGAATTAGCTGTTCTCTTTCATTGCCATTAGAGGGGGTAGTACAGTTAGCTACTGGTAATCCATTTTCTTCTCTCAAGGTATGAATTAAAATCCCCTTCCTTTTATGGCCATAAGCTACATCCTCTCCTCTACCCTGACCGGGGTAAAAAGAGCCGTCCACGGCTGTGTAGCTCCAATTAATTAGTCCTTAGTTTTCTGGAATTCCTAAAATTCGTCCTTGTAGGTATTTGAGAGTTCTATCTTCTTCCTAACGCTTCAGCCATCTGTGTACTGAACTCTTGGAGGCCCAAATCTCTCAAGCTGGTACATCACAACAATGACAACCTATTATTAATATGTAGAGAAGAGTATGATTTTACATATCGTACGGGGAGTATGAGGCACACGTTTACCTCTTTTTTGTGGTGAAATAGGAAAAATATCTTCAAATAACTTCCAGTCTATGTCACTTAATCCTTTAAATTTACCTAGCATCTTTTTTCAATTTACCATAACTGAGTAACGCTTATCGTAGTATCATCATTTGACTATTAGTGGGATAGATTAGTATAATTAAGCAATGCTATAACAGGAGATAAGTATGGAAGATAATGCAAACTATAAGAATGCCGTTGATATTTTGAGTACAATATCTATTTTAAAGGAATCCTTTTCTGTTACTGAAATAGAACTTTTTGTAAAGCTGACAAACTTTCAAAGATATAAAGCAAAAGTTAAGATTATCTGTCAAAGTGAGCCAGCTATCTCTATCATTTGTCTGATCACCGGCGAGGCTCGTGTTATTTCCAATGATTACCAATTGGCAATATTAAGAGAAGGAGATATATTTGGAGAATCAATGTTTTCGAATGAATGCATTCGTACGGCTAATGTGATTGCGAGTACAGATGTCTCTGCTATCATATTTACAGTAGAAGATTATGAAAGACTAACTAGGATTTCTCCAAACATTGCTCTAAAGTACAAGCTTTTTTTTGAGGCAATTTATAAATATCACAAAAGAAAAGATGATAAGTTTTTCTCTGTTGATTCCACAAAGTATCTTGCCCTTATTGCTCATAATGAAATGAAAAGTAGCTTGGTTGAGTTTGTGAAAGAACATATAAAATTGATTACTAAATTCCCACTTGTGGCTACAGGTACTACGGGACTCCTTCTTCACCAAGCAACAGGTGTGGTACTTTCTCGAAAAGTAAAGTCTGGACCTTTAGGAGGGGATCAAGCCATTGGAAGCATGATTTCCACAGATAATATTTGTGGTGTATTGTTCTTTCGTGATCCTCTTTCTTCACACCCTCATCATGCGGATATTGAGGCCCTATCAAGATTATGTGATGTCTATCAAGTTCCTTTGGCTACCAACCCTTCTACTGCTAAGGCTATTTTATTGTATCTAGACAATACTCCTTTAGAAGGTAAGCATAATTTCAGTTTAGCATTGACAAAATATCAAGAAAATCAAAGTCGTATAGTTCACGGGGGGGTGACAAGCAGCTTGAAACCATTGGGAGATAGTGATTATCCAGATATTCACTCTGTCAAAAATTGACTTTTTTTTGAGAATGATAATTATTCTTTCTAAGATATGGGTTAGCGATATAGCTGCCGCCACCATCCTCCGTCAAGGCTAATTCACATCACCGAAATTAGGTTGATTTATTATTCAATAATAAAATTACATCACATTAATGTAAATCAATTAAAAAATTTTTAATAATCAGATAAATGGCTAGACATTGACTGTAAATAATTAGATATTATCTAACATTGACAGAGCTTTTAATCCCCTTTGATAATCAGACTTTTTTTTGAGGACTAAGCTTTATTATCTGTTAAACAATGTCAACTAAATAATTCCCAGCAAGTACCCATAATTCACTATATATACCTACCCAAAAATTACTATGTCTTCTGTCTCTTCGTCCTGGTTCGTTTAATCGACAAATATATCTTTGACATTCTAATTTTTTAATATAATTACCATGATAAAATGAAGCAGTGTAAGCAATGGCTACTAATAGAATTAAATTAGTCAAACGTTGTATATTAGCCTGACTACCTTCTAGGTTATATCCTCCTTTCTTACAATCAGACAACATAGCTTCAATACACATTTTCGACCGATAATTTTTGATAATTTCATCTTTTCAAGATTTGTCAACAAGTACCAAATTTCTTTCTCCATTTTATTTTTATATTTTCTTTTCCAATAGGTAACTCAATTAAAATATCCAAATCCTTTTCGACCGATAATTTTTGATAATTTCATCTTTTCAAGATTTGTCAACAAGTACCAAATTTCTTTCTCCATTTTATTTTTATATTTTCTTTTCCAATAGGTAACTCAATTAAAATATCCAAATCCTTTTTTATGAGTAATATTAATGTTACTTAAAAATATTTAAGTTCCCACAGATACGGCTAAATCAGTGAATTGCTGGTACTTTTTACCAGTTTTTATATAGTGAAGATTCATTTTTTTCCTAAAAACAAAAGAATTTTTTTGAGGTAATTTTAGCTTTTTTAGCCAGTTTTATAACTCTACACAATGGAATTATCGATCTCCAATAACTACAAGCTTATATTTTTTTATAACCGTAAAAATAGTTTAATAAGTAAATTTTTTTCTGCCAAATTACTAGAGCTTTTTTTATTCAAAACTAGCCAATAAATAGGTGATGCTCGTTACTAGCCAATAAATAGGTAATGCTCGTTTTTTATATATGAAAGCAATAACGAATATATTACTATCTTTCCATTGTTTCTTATCTATGGTAAAAATCAATTTACTACCATCGGGAAATTATAGACTAATAATCATAATTATCATCGGCAACTACAACAAGGGAAAGCTCAAAAATATAATGTTAAAAATCTTTGTATATGTTTCCGGCGACTCTCATATTTAATTGGTAAAGGAAAACAGGCAACTAATCTTTCTATTTCAACAGTTTTGTGAAAAGTTAATAACCAAACTAAAATTTTTCAAGTTTGGAATTGACTTTCAGTCAAAGATTATTGAAAATCTGACTCAGATAATGAAAAAAAATCCATTGGGGTCGGTCTATTTATATAAGTGGACTGAATTTTTTTACCATATAATGTGATTTGTCGCTACCACAAAGGTTGACACAAAAATGGTAATATTGGTTAGTGATCTCTAATCTACATCTTAAAAAGAATAATTATTATTCTCAGAAAAAAAGTCAATTTTTGACAGAGTGAATATCTGGAAAACCATTATCTCTCAATAGTTTCGAGCTGCTTGTCACCCCGTGAGGTAGTTAACCTAAGTAAGCCCATTTCCGGTTATCCGTTTATAGGGTTTGGTTATATTCAGAACAGGACATAAAACTTTCACTTCATCACGACTCCTCTCCTAAACGTCCCAATTCAAGAGGACATCCTTAAATTCCACCTTAGACCTAATGAGTCCTTAATTGTTAACTGCTTTTAAGTCGTTGGCATTTTTAAGGTCGTGGCAATGACAGGGCAACAGTTGTTTATTCTTAATTGTAGCGAGCGCCTAACTACAGAAATTGAAAGCAGTTTGCTCTTTTTTTTCTCTCAATATCCAATCTTACAAAAAAATAGCGCGATCGCGCCAGAGCAAAAGCTGTTAGATCTCTAACCCAAAGACGATGTAAAAAAAAATATTACTCTGGAAAAAACAAAAATCATGCATTAAAAAACAAAATAATAACTACATAAAGAGGAACATAAATAGTAGATTTGATAATTGGATAAATAGGGCAATAAAGCGATATAAATTTACCCATAAAATAGCCAAAAAAATTTTATAAAAAACAAAAATTTTAGAGAGATAAAGGAGCTCAAGAAACTGAGAGAACTAGGATATCGAAAAAAGTCTATAAAAAAATAATTTTTCCCATAAATTCAAGAAGATAACAATAAAAAATATCAGAAAATAATATTTGTGGAAAATGTAATGTGGAACATCTAATTAGGTTGATAAAAATATTTAGAGTAGCCAGAGAAATATAGCAATCCCATATTGGTCGCAACAGATATAATAGTAAGAATAACAGATCTAAGAAAAAGACAAAAAATGAATATTATAGATAAACTAAATGATTTTATTAATCAAACAAAAGAGTCTAAAGAAATTAAAAGGGCCTTGGCCGTAAAAATGACCTTGTCAGGAAAATCCTACCATGAAGTCAAAGAATTATTAAATGTTTCTCACAGTTTTATTAGTGAATGGAAAAACCAAGCATTATTTCATGGTGTAGAAAGTTTAAGGCTTCAGTATCAAGGGAGACAAGGTTACTTAAAAACGGTCGAAAAAGAGAAAACAATTGAGTGGTTGAGAGCACAAGATTATCTTAGGTTATCAGATTTAAAAAACTACTTACAGGAGCAATATGATGTGGTTTTTGAGTCTAATCAAAGTTACTATAACTTGTTTAAAGAAGCGGGCATAAGTTGGAAAAAAACTCAAAAAAAGAATCCTGCTAAAAATGATGAATTAGTAGAAGTTAAAAGAAAAGAAATACAGGAATTTTTAGCTAAATGGCAACCAGAAATAGAAACTGGAAAGCTTACAGTGTTTATGATTGATGAATGTCATCTTCTATGGGGAGACATATTAGGTTATGCTTGGGGAAAAACAGATGAAAGAATAGAAATTGCAATTAAAAATGAAAAAGAAAGACAGACTTATTATGGAGCTTTAGACTATAAAACCAAGGAATTTCTTGTGCAAGAATATGAGAGTGGAAATACTAAAAATACTATTGAATTTATTAAATATTTGCAGAAGCAAAGACCGGGCAACAAATTGGCAATATTTTGGGATGGGGCAACTTACCATAACTCTCAAGAATTTCGAGAATATTTAATGACAATTAATCAATACTTATCAGAAGAAGAATTGTTGATAAATTGTACAAGATTTGCTCCCAATGCTCCGGAGCAAAATCCTGTTGAAGATATTTGGTTACAAACCAAAAATTTCAGTATTACTTTTTATCATCTTTGCAGTTCTTTTAAAGTAGTTAAGTGGCTATTTAAGTTTTTTGCGGATGGTCAAATATTCAATTTCCCAAAACTTTTTCAGTATGAAATTTTGCCGCAACCTACTTAGGATTGCTATATTCAGATTAAAAGATAGTAATTATCAAAAAGTAATTCTAACAATATGTGGTTTACTCAAACTAAGAATAGGAAAATTAATTTTAGTCGAAAATTTCAATAATTGAATTAATAAAAAGAAAAAAAGATGCAATAAAACATTTAGTTATTAACAATAAGTACCTCAAAGACTGATAATGGTGTACAACTAGCTAAAAATGCTTGGCAATTATAAAAAAGCTAAAGTCAAACGAGACAAAAGCTTTAGCAATTTTTGAATATGTCTAATAGTCCGTAATTAACTTACCTGTCTTAACCTCCGTTCATCATAGACCATACTCAAATTATGAGAAATTATTTCCCAATAGACAGGATAACTTTCTTGAGTATAAACCTCTTGGGCTCTAACAAAACAAGCGATCGCCTGCTTGAGATTATTTTGTTTATCTCCCATCATCCGATCTAGATAAACATTTCCCAGATTATTTTGAGTAGTTGCCCAGTCTAGGGGAAACTGTTCCTTAGTCCGTACTTTAAGAGCAAAAATATAACAAGCGATCGCCACTTCAATATTTTCCTTTTTTTCTCCAGCAATACGTTCATGGTAAGCACTACCCAGATTATTTTGAGTAGTTGCCCATTCTTGAGGCAACTTCTCTAAACGCCTCACAGTTAAAGCTTTCTGATAACAACTAATAGCATTTTCCAAATTTTCCTTTCTTCTTCCGGCAATACGTTGTTGATAAGCATTCCCCAAATTATTTTGAGTAGTTGCCCATGTTTCAGGCAACGCAGAATTAGTTCTAACTTCAAGAGCTTTATCATAACAAGCGATCGCTACTTCTATATTTTCTTCTAAGTTTCCAATAGTACGTTTTTGGTAGCTACTACCTAAATTATTGTGAATAGTTCCCCAAATTTCTGGAAATTCTTGACAGCTTAAAACTTTTAAAGCCACTTCATAACCTGCTATTGCTATTTCTACATTATTACTTTGATTTCCCAAAGGAAATTGTAGAATTAGGTTACTAAAACTAATAATATCTAGAGCGATATTTTGCGCTAATTTTTGCTCCATTTTTGGCAAATTTTCACCAGCCCAAGTTTGTATAACTTTGAGAAAATTTTTATTAAGTAGATCCTGATTATATTCTAATAATGAATAAATATTTTCTAGTTTTACATCATTATCAGATATTATTTGTAATACCTGCATCAAGAAAATTATATATTTTTTTTCATCTACAGATAGGGAAATATTTTTTAAATTTATCTCTAATATTGCTGCCAAATTTTCCAACCATTGAGCATGCAAACCATCTATTTTTCTATTAAACTTTGCTATTTTTTTCATGACTTGAACTAATCCCAAATCTAGTAAATCTTGATTAGCTTGTAAGATTTTATTTTCATTACCAGAAGGTGAAACTAATAAGGACTGAACTAGACCGATGTAACTAGAAATTTGTGGTTGATGCATATTTTTTACCTCAGAGTTTTGTTTGCTAGACTCCGCTATCTATTTCTCATAGTAATTCCTAAAAATAATGTAATACCTTGCTCAAGACTTAAGTAATTAAGTAATAAATAAATAAGTAAAGTTCAGCAATATTTTTAACTATTCTAGGGAAAAAATCTAATTACTCTTATTTCCAAGAAGTCTAATTTACTACTAAACTTGTATGGAATGCCCTTACTTACTCTCAAGAAGATTTAGCAATAATTTTGATATTTGCTATGAGGTAGATATTTTTTATTTATTTACAATTGATGGTTACCTTGATAAAAAAACTTTTAAAGAAAAATTTATAGTTAGTAAAAATATTAGATGGTAAGTTTGTATAATTTCAGAGTTAATTAATACAGTAATTTACTGTTAACTCTTGTAATATAACCGATTTAATTCCCTTCTTCTTTCAGACCAAAACAGGCTTTTTTTTATAATATTGATAAATTTACTATTTACTATCAAATACTTTTATAGTCGTTTTAATTAAAATTGAAACAAAAATTGAGTATAATAAAATCAAGTCAACTAGAAACTATTTTGAACTATTCCTTACAGTTTAGACTTCAGATAAAAAGTAATAAATTGTGTATAAAATGGCGGTACAATTACCAAAGTAGCTCATACATTTGGGATAGGAATAGCTTCAATATATAGATAGTTATCTCGCCCAAAATTGTCAGCAACTAAGGTAACAATTAGTCAAAGAAAATTAGATTAGAAAGAATTAGAAAAAGATGTAAAATCAAATCCAGAGTCGCTCATTGTCAGACAGAGCTAAAAAATTTGGAGTTAATCAAGCAGCTATATTTTATGTTTTAAAAATAATGAATTTTCCTTAAAAAAAAACAACTTTGTTATAGAGAAAGAAATAGAGAATAAAGGATAAAATATTATCAGCTTTCCCTCGAAATTTTATCAAAAGATTGGGAAGTAAAAGCCTTGTATTTATTTATGAATCAGGATTTGAAGATAATCAAGACTGTATTTATGCCTAGTCAAAAAAAGGGAAAAAAGTTTATGGTTAGCAAGAGGGAAAACGAGGTAAAAGAGAAAATTTAGTAGCCGGGAGAAGAAAAAAGGAAAAAGATTTAATAGCACCAATTATATTTAAAGGAACCCTAAATACAGTGGAATTTTAATAATGATATGATCAACATTTATTACCATCATTAAAAATTTCCAGTGTACTGCTGCATGGATAATTCACCATTAATTACGAAAAAACTTTATTAGATAATTAGTAGAAGCAGGGGGTCACCAATTAATATTTTTGCCAAAATACTCTCCTGATTTAAATGGCTAAGAACATGATTTTAGTGCATTAAAAAGAGCTAGAATGTATTCACCTATCAATACATCTATTGATAAAATTATTCGTAATTATTGTGCCAGATAGTGTCTCATTCTTATTTAAAGTAACTATAACTTATGTCAACTATCTCTAAGCCTATTTAGGCTCATTAAGTATTGTATATATCTAAAATTAATATTTATATAAACTTCATGGAGTATTAGTACATCTAGGTAAAGCTTTTTTGCTTAAATTATAAAATTTTATAAAAGTTACTAGAGTAGGAAGTGGAGGAAGCAAAACTAACAGGTAAAGTCAAAAAAAGTCTGTGAAAGTAAAAGAGTCAAAAGTCAAGAGTTAAAAGTTAAGAGCCAAGAGCCAAGAGTCAATAATCAAGAGTTAATTTTGTCTTTAAATACCAAATAGTGATAATCTATTTCAAAATTATAATCTTTGAATTGCTAAGTAAGTATTTCGTCGTCAGTTATGAGTTATTAACTCATTATCACACCGAAAAAGGAATTAGTCTCCAAAGAGAATTAAAATCCATAAATAAATATGAATAAATATGAATAAATATAAAGTAAAAAGTCACCAACTAAATTCTTGACAAAACTGAATACTTAAATTTTTAGATTCTATTAAGTTTCTTGAAGTAAACACTGCAAAATATCTATCCAATGACAAAACTAATTATTCAAATACCTTGCTACAACGAAGAAGAATGTTTAGGAGTAACTCTAACTGCTTTACCTCGAGAAATACCAGGAATAGACATCATTGAATGGCTAATAATTAACGATGGTAGTCAAGATCGAACAGTTGAAATTGCTAAAGAGTATAAAGTAGATCATATTATTAGTTTTCCCAGAAACCAAGGTTTAGCCAAAGCATTTATGGCAGGTTTAGAAGCTAGTTTAAAAGCAGGAGCAGATATTATCATTAATACTGATGCAGATAATCAATATTGTGCCGATGATATTCCTTATTTAATTCAACCTATTATTTTGCGCCAAGCAGAAATTGTAGTAGGTCAAAGACCAATCTGGGAAACTAAGCACTTTTCTTATACTAAAAAATTACTGCAACAATTAGGGAGTTGGGTAGTCAGAATAGCGAGCAATACAAATATTCCAGATGCACCCAGTGGTTTTCGAGCTTTTAGTCGTGAAGCCGCCATGCAACTTAATGTATTTAACTCCTATACTTATACTCTAGAAACAATTATTCAAGCAGGGCAAAAAGGTATAACAATAACGTCAATTCCTATCAGAACAAATAGTGTATTAAGACCTTCCAGACTAGTTAGAAGTACCCCTTCTTATGTATTGCGTTCTCTATTTACTATACTGAGAATTTTCTTACTTTACAAACCCCTACGTTTTTTCCTGATGTTAGGAAGTTTACCCTTGAGTTTGGGAGTAATTTCTGGTATTCGTTGGTTATTTTTCTTTTTTAGTGGATATGAAAAAACCAGAGTACCTACTTTGATTTTAGCAACAATATTAGTCTTGGTTGGATTTCAGTTATGGATATTAGGTTTAATCGCAGATTTAATGGCAGCTAATCGTATAATTATGGAAGAAATTCAAGTGCGAATGCGCAGGCAAGATTGTAATAATAATAATTACAAAAAGTAACAGAATTTAGGTTTATAATCTTGCTCCTAACTTTTTGAATTCGTTTTATGGATAAACTCTAATAACTTCTTAATGTTAATAGTAATTAAATACTTTATAGGATTCTGTAGGTAATTTTTTTACAGTAAATATGAGAATGAATAATTCAATAGTTATCTATCAATATTTAGAGTAATTTTAATTATTAACTTTATAAGAACTGATTTGTAAACTTAGCTGAGAGTATTAATATTATCTAGCTTTTAGTAATTTGGGGTTGACTGGAAAAACTTGCAAAACCTCAGCATAAGTAGGTAGGCATTAAAACTTGTTGCTATACAACAAAATGTAAATTTACTCTCAAATACACTGTCCAGAAGAGCTTGTAGTTACTTGAAAAAATTTCACATAGTTAAGGGATTTCTTTGCCTACTTAACTTAACGGGACTTTAGTGAAAAAATAGTAAAAAAAAGGGTATAATGTATACCTGATATGTATTTTACGTTAATTACTGGCCTGGGAAAAGTTTGATGAAAGAAACAACTTCAGTGGCCATGCCCTCTTGTTTCCATCGATGGTGCGATCGCTTTAACAATGTCTTTAAAACAAAAGCCCAAAAAACAGGGTTTAGGGAATATATAGGAGGATTACTCTTGAGAAAGCGATCGAAAAAACTTGTCTCAAATTGCCAACAACACTGTAGGTCACACGTACCACAAATTACGGCATTTTCTAGTTCGAGCAAATTGGTCTGTAGATGCTGTGAATGAGCGTCGTCTTCAAGTAATGTGGGAACGTCGCCAAACAAAACCTTCTCGATCCTATTGCTTTAATTATAGACGATTCAGGCCACAGAAAAAGTGGTAATTTTACTGCAGGAGTAGGGCGGCAATATATAGGAGAAATAGGAAAAACAGATAATGGTGTAGTCGTGGTGACAACTCATCTTTATGATGGAGTTAAAAGTCTACTTTTAGACATAGCTTTGTATCAGAAAGCTGATTCTTTTCCAAAAGGAAAAAAAGACCCAGAATTTGTCAAGAAACCAGACGAGTGCAATGTCTCTAGTAGATCAATGTTTGTCCAGAGGACACCAACCAGAAATTGTGTTAATTGAAATTTGGCTATGGTAACAATACATCATTCTTAAATCAACTAGAGAAAAGAAGTTTAACTTATATAGGAGGATTAGCTAAAAATCGAAAAGTCATCATTAAAAAACAAGATGACATTAAAGAGGAAATTAGATTAGACAAGCTGGCAGAAAGTATACCTCAGAAAGCTTTCAACTTAGTTCAACTAAGTACAAAAAATGCTAGAGAAGTTTGGGTAGCTACATTAGAAGTAGAAATATCTAGGATGTCAGGTCAAAAAACTATAGCTATCGTTATGAATGCTAAAAGTTTTTCTGAGGCCACTGATATTAACTATTATATCACTAATAGAGAAGACAAATATGTAACTCCTGAGTGGATATATTCTACTTATTCTCAAAGAAATTGGGTGGAAGTTTTCTACAGGGAAGCCAAAGGATGGTTAGGATTAAGAGAATATCAAGTCAGAGATAAAATCAGCCTTAAAAGGCATTTTATTTTAGTATTTTGTGCTTATACATTTATTATCTGGCATCAGTTAACAGGAGGTATAAGAAGGCGTTGGGCTAACAAACCATTAAATACGTTTACTGATACTTTAGAAGCATTTCGTACCGCAATATCTTATCGTTTTGTTGAGTGGTTAGATGAAAACATCGACGTATTTACCGCTCATAAAGAGAGTTTAGGGTTTGTTTGGGCTTGAAATTTGCTAAAGTCCCGTTAACAAGAAACTCAGCTTTTCAATATTTATTCTATAAATCAGCTCTAATAGAGATAATCGCATTAAAATGAATATTATACTTTATTAGCCACCGAATATACTGGAATTACTCGTATTTATAATAAAAGTAAAATCAGATAATCTGTTGACTAAAGTTTTAAATTGAGTAAGATATAATCCTACTATTACTTCTAACTTTTAATCACCAAAACCTAGAAATCTCTAACTATTAATAGTCATGAAATACTTTCTAAAAATATATAGCAATCCGCGCATAGGTTGCAACAGATATAATAATAATAATAACATATCCACTTCACTAGACAAAAAATTAATATTTTAGATAAACTAGACGATTTTATAAATAAAATATGCATAGTCAAAAGAAATAAAAAGAGCCAAGGCATGTCAAAATAATTTTTTTTTTGGAAAATGATAGTGTGAAATTAAAGAATTATTAAATGTAACTCAGCAGTTTTATTAGTGAATGGAAAAATCAAGCGTTTCATGGTGTAGAAAGTTTAAAGCTTCAATTATATTGGAACATAAGGTTACTTAAAAGCTGTCGAAAAAGAGCAAATAATTGAGTATATGAGGACACAAAGTTACTTAAGATCATCAGATTTATAAAAATATTTAAAAAAGCAATATTATGTAGTTTTTGAGTCTAATCAAAGTTATTATAACTTACTCAAAGAAGCGGGAATAACTTGGAAAAAAACTCACTCATATAAATCTAGCTGAAAATGATTAATTAGTGAAAGCAAAAAAAAAGAAATAGAGAAATTATTGGTAAAATAAAAATTATAAATAGAAGCTAAAAAGCTTGTAGTGTTTATGGTTTATGAATGTTATTTATTATGGGGCTATCTCTTAAGTTATGCTTGACGAAGAAAAGATAAACGAAGAGAAATTCCTATGAAAAATGAAATAGAAAGACCAACTTATTATGGAGCCAATTATTATCAAACTAAGAAATTTATTGTGCAATAATTAAAGAGTAAAAACACTGAGAATACTATTGAATTTGTTAAATCTTTAAAAGAGCAAAGACTGGGAAAAAGATTGGCAATATTTTGGGACGGTGCAAGTTATCATAACTATCAAGATTTTAGAGAATATTTGATGTTAATTAATCAAGAAAAACCCGAAGAAAAATGGTTGATAAATTGTCTAACATTTGCTCCGAATATCCCAGAACAAAACCCTGTAGAAGATATTTGGTTACAAACCAAAAACTTGATTAGTCAATTTTATCATCTTTGTAGTTCTTTTAAAATAGTTAAGTGGTTATTTAAATTTTTTGCAGACGGTCAAATCTTTGATTTTCCAAAACTTTTTCAGTATGGAATTTTGTCACAACCTAAATAGGATTGCTATATAATAAATTATGGACAGTAAACTAGAAACTGAATAATTCAATAGTAAACCATTAATATTCAGAATAAATTCAGTAGTTAACTTGATAAAAAAGATGATAAAATATCGTAGTATTTATAATCAAAATAAATATAAAATTATTTCAATAAAATCATATTATTACTTCTAAAGCTTGTGCATTAATTTCATTTAAAAACTTAAAATATTGGTATAAAAAATAGAGCTTAATATTTATTAAATATATAAAAAATACGAATAATATATAACAAATTTATATATACAAAATTAGCAATAAAATTTTCTATATTTGGTATAGATTAGAAAAAATGTTAACAATAAAAACTATCAGATTATAGATATGAAAAATCCTAATATACCCATAACAAACCAAACTAAATTATCAGATATAGAATCTGATTCATTCTTGAGTAAAAATGATATAAATAACACCGAAAAAATTAAGATGAGAGACTTATTTGCTCAAGAAGCATTAGCTCAAATACCAAAAATTTTGACATTGCTAGACCGGAACTTACATAGTCCCACCTATGGCTGTTTTGACCGTAATTTTTGGCATTACAAAATTATAGACTTTCCCAGTGGAATGGCTCAAGAATTTGTCTTACCTTTAGCCTTAGCTTATAGTTTAAAAATTCCTAATAACCCATATTATCATCAGGAAATGATACATAAATGGGTAGAAGCAGGAATTTTATATACTTCTCATGCTGCTCATCCTGATGGTTCTTGTGATGATTATTTTCCCTTTGAACGAGCTAGTGGAGCTACAGCTTTTTCTTTACTAGCTAGTATTGAAAGTTATCAAACATTAGGATTAAATAACTATAAAATACTCAGTTTTTTTGAAAAACAAGCTGACTGGTTAGTTCATCATTATGAAAATGGCAAATTAGCTAATCATGAAGCATTAATTGTTTTGTGTTTAGAATCACTAAGTATATTATTGGAAACCTCAAAGTGGGATACAGCAAAAGCAAATCGTTTGTCAAGATTATTAAGTTGGCAGAGTCAAGAAGGATGGTTTACAGAATATTCCGGTTTTGACCCTGGTTATCATACTCTTACTATATCTTGTTTAGCCAGAGTTTATGAATTAAATCCTAGTGAAAAATTAAAATCTATTATCATTAAAGCAGTCGAATTAGCTACCCAATTTATTCATCCTGATGGCTCTTTTGGTGGAGAATATGCTAGTCGTAATACTTATAACTTTTTTCCTCATGGATTTGAATTAGTCGGTAAATGGTTACCTGCTGCTTTGTGGATTAACGATCAATTTTTAATAGGCTTAAAAAATGGTTTAGCTCCTTGTTATGCTGATGATCATATTATTGGTCATCATACCTGGAATTATTTATTGGCATGGCGAGATTTTATTACTGAAAGACCTGTTAATATTAATCGTGATGTTGCTAGTCTTTTGTTAGAAGAAGCTAAAATATTGATTAAACGACGACCAGGAATAGAATTATATGTGAGCTTAAATAAAGGTGGTGTTTTTAAATTATTTCGTAACCAAAAATTAGTAGCTTCTGATACTCATTTATCCCTACAAGTTAGAAAAGGGAGAAAAATTCTTAATGCAGTTAGTCATCTGAGTGGTAATTATGATGTCGACATATCTCAGGATGAAATAGTTATTTCTGCTAATATGGGTTGGGCAAAACAAACTCAAATGTCATCTCTTAAGTTAATAATTCTGAGATTAGTAATGTTAACTTTTGGGCGTTTTTTCCCAAATTTAATTAGAAAAATATTACAAAAAATTTTAATTACTGGTAAACAAGATGCGCCTTTTTCTTTCAAGCGCCATTTTAAATATAAAGATGGAAGTTGGCATATTACAGATGAACTTTTTGCTAAGTCTTGGTTGGATGTAATTAGTGCAGGTATTGGTTGTGATCAAACCTCTATTTATGTTGTAATGAGTCGCACTTTTCAAATTAGTCAATTACAGTCTTGGCATGATTTAACAACAGAAATTAAAAAACTTTCCCCTGGCCAGCCCTTGAAAATTGAACGTAAGTTTTGACTTATATAACTTTTGTTTGAATAGGAAAAAGAGCAGAAAGTAGGGATGTTCTATGGAGTATCCCTATAATTAAATTTGATTTATTAAGATAATTGGATTTAATACAAATTCCCAAAAATAATCCAAGACTTTACTCAATATTTCAGTTATTCAGTCAGTAAGACTACAGCCGCCAACTACGATAGAGTATTTTTGAAAATTACAACCATTGTTAAATAAACAATTATTCTAAATAAGGTTTAATTGCATACTATTTTAGTTTATTATATAAACTTTTCCATTCTATAAATCATAATAACTACCCAAAATTTTTAGTTGATTTTTTTGTACTAACTGGGTAATTACTGGAGAAAAATTTATGATTTTAATTTGCTAAATAAACAATTATTCTAAATAAGGTTTAATTGCATACTATTTTAGTTTATTATATAAACTTTTCCATTCTATAAATCATAATAACTACCCAAAATTTTTAGTTGATTTTTTTGTACTAGCTGGGTAATTACTGGAGAAAAATTTATGATTTTAATTTGTTAAAAAATATTAGGTTGAACAGTATTTTTTACAACATTTCCTGTTTACCTCAAGCAGCTTCTACAGCAGGCTTAATTGAAACACTTCTACTACCTATTTGAACAGGAAAAGTTATCCAGCAGCTATTATTTTTTTGACTGCTCAAATTTTTTTATTTCCTAATACCATTAACACTTTTAAATCTAATATTAAAGTGCCACATTCTATACTACTAATTTATTCGGTAGTAGCAACATTTCCAGCTTTTATAAGAATAAATAAGTCTCCTAAACCTCTATCAAAAGTTATCTCAACAGGTACCTGATAGTCTGGGAAAAGATAATAGTAGCAAAGAGGTTGTGACCATCAGTAACTTCTTTTAATCTGGCAACACTTATAGTCATTTTAAATAATAATGAGACACTATTTGGAATAATAATTACGCATAATTTTATCAAGAGATGTGTTGATAGGTGAATACATTCTAGCTTTTTTTAACGCACTAAAATCATGTTCTTAGTCATTTAAATCAGGAGAATATTTTGGTAAAAATAGTAATTGATGATTCCTTGCTTTTACTAATTCTCTAATAACCTTTTTTCGTTAGAATTGGTAAATTCTCCATAATTAGTAAACTGGGAATTTTTAATGCTCGCAATAAATGTTCATTTAACCATTGTTCACATCCCACGGCATTTAGGCTGACTTTAAATATAATTGGTATCATTAAATCTTTTTCCTTTTTTCTTCTCCCAGCTACTAACTTTTCTATTTTTCCTCGTTTTCCTTCTAGCTCACCATCAACTTTTTTCCCTTTTTTTGACCAGGCATAAATACAGTCTTGATTATATTCAAATCTTGATTAATCAATAAATACAAGGCTTTTACCTCCAAATTTTATCAAAAAATTTCGTAGTTTATGATAATATTTTCTTCGTTCTTATCTATTTATTTCTCTATAACCAAGTTATTTTTTCCAAGGAAATTTTATTCTTTTCAGAGCATAAAATATAACTTTAGGATTAACTCCAAATTTTTTATCTCTGTCTGCTAATGAGCGATTATTTATTTGGTTTTATATCTTTTTCTAATTCTTTTCAATCTAATTTTCTTCGACGACGTTTTACCTTAGTTGCTTCCAATTTTGGGCGAGATAACTATCTAGATATCGAAGCTCTTCCTATCCCAAATATATGAGCTGCTTCGGTAAGCATACTACTATTTTCTACAAAATTTATTACTGTTTATCTTAAGTCTAAACTGTAAGGCATGGTTAAAAATAGTTTCTAGTTGACTTGATTTGATTCTACTCAATTTTTGTCTCAATCTTAATTCAAATAACTATATATTAGAGTTTTTACATTTATTTTCAAAAAATCTTTTATTCCCTGCCATTAATATTGCCAAAATTTTATCTAGAGAAATTTCTGGAGAAACTTTAATTTAGTCAGGCGTTTTTGGTTTTACTTCTGGTTATTGAACATTTTATTTTTAGCAGCTTAAAGCTAAACTTGTTACTTCTGTTGCCATAAAAAAAATTTCATAAATTTTGTGTTTTTTTCAGATAATTTTAGTCCTAAAATTTTTTGTATTTGTATCCTATTAGAGTTTTCCTTAACAATTCAATTTTTATGTTTTTCCTCTAAACTATACCAAATTTCAAAAAAGTTTTTTCACTGAGTAACAAGTCCCTAAGAACCCTTTTTCAATAACTATTAAAACTCAAATATTTGTATTTATAATTAAAGTTTTTTTGATAATTATAATCATTTTTGTAGCAGAACGTAATTTCTATCACTCGCCCACAATCCCATATTTAAGTTTATTTATTTTTCAATTAAATACTGAATACCATTTATCAAAAACTTTTCAACATTTTATTAGATAGGAAAGTAGGTTAGTAGAGTAGTCTAAATATTGCATCAAGGCGTCCGTAAAACATAATAATAATTATTATTATTGGGATATACTCAAGAATAAAAAAACATGAATTTTGTATAACTCTATTTGATTAACTTACATCAAATTTTGGTAATAATTTATCCTAAATTATCTATAATATAGATCCAACATAAAATTAAGGAGGCTAAACAATTTTATAATAGTACTTATTTTGACTTAATCTCTATAGCCCAATAAAATTTAATTAAAGATTTTCTTTGAGTTCTGTAGTCTAAAAAGCTCATCTAATAGTTCAATAAGTTTTTATATTCAACTACGGCCAAATATTTTTTTTTACTTTGACGTAATTCCTAACTAATTTATTAACCTTAAATTATCTATCCTTACAGTTATTAGTTTGCCATTTCTAGTTAAACAGGAATTAGCATTGCTAATACTTGAGAAATTATGGGAATTAATTCCAAAATAGACATTTTTTTCAAAATTTATCAACAAGGGAACATTAATATGTTGTGCAAATCGTAACCAGCCAAAATAGTCAGTTAAAATTACATATACAACCTTTGTTTACGTAGCATTTTGAAAAAAAATACCATCCTCAAAATGCTCAAAATTAGTTAGATTTTTTATTGGTTTTGAGATTCCATTGGCAAACAAATAAGATTATCATTCTGAATATAAACTAAGCCTTGCTGACGTAATTTACCTATGAGACGAGTCACAGTTACACGGGTAGAACCAATAGCGCTACCAATTTGAGTATGAGTCAAAGGCCAAGGTAGATAATAACCACTTGTTACTTCTAGGTTATCTTGACTAGTCCAGGGTTGCCCATATTCTTCAATTAATAGTGTGAGAAATCCAAATAATCGATCAATAGTACGACGTTGACCCAGAGTACTTAGCCACAAAAGCTTCCTTTGATGTTGATAGCGAAAAGCGTCTAAAACTTCTCTGCGGAAGTGAGGCCAGTTATCCAGTTCATGCCAATACATCCAAAGTACAGTTGTTTTATCGATATGAGCATAAGCTTGTAGCGTAAATGGTGACTGAGCTATTAGTTCAAATGGTTGACCAGCACCAACTAATCCTAGAAAAGGTTCATCTGAATTTGGACTTGTTTTTGATTTGCTAAGGTTATTATTACTAACATTTCGATTGGCACTTATGTTGGCATTACCTACCAGACGAATTGCTCCTTTCTGTATTAGATACAGCAAACCTGGGCGAGCGGGAATACGTTCATCTTTGCTGAAAGCTCTACTACGGTAGTGTTCTTCTGCCCAATCTATGATTAGTTGCCAAGTCAAAAATGGCCTGTTGTTCAGAGCAGAAGTATTAGTATTTTGTACATTTAGTGACATTTCTGGTAGGTCTGGATGTGAAGATAGTTGCATTTTTACTCTGTTTTAGTAAAAGTTGGACTTAAGTAATAACAATTGGATCAAGGACATAGGAGCAGATATAGCATAAGTTATAAATTTAGAAGGCGAAAAGTTAAATTTGCAGTACGAACTATAATTTGAGAGGCGTAAAAATGTCTTAGCCACCATGGTAACTATAATATTAATATTTTTGCTTATATCCGTTTTATTCCTTACCTCAGAGTAGCAAAAAACACATCTTTTTATGAATTTTGTAGGATAAATTTTATTCAAGGTGGTGGTAATTTTGACAATATTATCATTTCAGTGTAATGCGATACATTTTCTGCAAAAAGCTGTAAGTTTATATCGAGAGAAATTAGAATGGTCTTATAGCTGTGAAAAAAAATTAGAGGTTTTGGCAAGGATAGAGATAATTTCAATGAAACAAGTTAAAAATTGTGGAGGAATTATATATAAGTCAGCGATCGCTCTCAAATTAGCCCCAGTTTTGCAGCAACCAGCAATATATATTGCTACTGAGTTAGCTAAATATTGTCAAGAAATAGTTAGTCTTGAAGGAAAGAAAGATGCACTAAATTTTGAAGTTGAAGTAATTTCATCTGGTATGATTTTCTTTAAATTCACAGGTTTAAGTATAGCTAACTGGTTAAGTTTTTTAACTTCTGTTCCCCTTAAGGGTGAGAGGAAAAAGCTTCAGGTTAGTGTTGAGTATAAATCTGATGAAACTACAAATTTGTTTCTTATTCAGTATAGTCATGCTCGTTGTTGTTCCCTATTGCTTATGGGTGAAAGGGATAATTTGATTACTCTTGCTCCGACAACTCTAGAAAGCTATGGTCAATTTTGGTTTATGACAACTGCTGACCCCATACCCTGGCAAAAATCTCATGGACAATTACAATTTTTAGATTATGCTGAATATGAATTAATGGCTGAAATAGCCTCTAGTCTAGATTACATCTACTGTATTTCTAGTTTCAAAAAAACTATAAATTGGGAGAAAGTAGCTAATTCTCTGAGTAACCGTTTTCAAGCTTTTTACCGTCAGTGTCGTATATGGGGTAAAGTTAGAGTGGAAAATCCAAAGTTAGCACAAGCTAGATTAGGTTTAGTTTTGGCAACTCAATCTCTACTCAAATTTTTATTAGAGGAAAAGTTAGGTGCTCCAGCTCCTCTAGAATTTTAGGAGAATTTATATAACTGAAGTTATTGAGGAAGTATATTATCATTTTTGGAGATTGGTATCAAGGAGCAGCATGACTAAAAATTTTACCCACCCTAGTTTGATTTTAATTATGCAGCATTAATTATAAGGGATTTAGTCTGACAATGTATGTAATTAATTTTGTGACTTGCTTACCTTCAATACAAAAATTTTGCTATTCTTTGAGATCATATTTCTGAATAAATAATATATATAGACTATTATTTATGTTTAAATAATCTCTGTAGTTTTTCTAGTTATTTTTACTATTTTTCAAAAGTAGCATAACTTTTGAGAAGCAGTATTAAGAAAGACATTTTTGTCTACTACTTAAAAAATGATAGTTTTTACACTTACGGAGGATTTTTATATATGAGTTATGTTGTAGTTTACGACGGTAACTGCAATCTATGTGTCACTTTAGTACAGGTATTAGAAGGTATAGACAAGGGTCAATTATTTAAGTATATTCCTATGCAAAATGATCAAGTATTGAATCAATTTAGTATTACCGCTAAAGATTGCGAAATGGGAATGATTTTAATTGATACTAATGAGCCAAAATATCGGTGGCAAGGTAGTGACGCAGCCGAAAAAATAGGACAATTATTACCTGGGGGAGATATTTTTGTAGCGGCATATCAGAGTCTACCTGGGGCTAAATGGATAGGCGATCGCTTTTATGAGCAAATTAGAGATAACCGTTATACTATATTTGGTAAACGTTCTAATACTTATAATTCAGTCTATCCAGTTGGTTGTAAAACTTACTTATTTCAAGAACAAGATTCTATCTAAAGATACAGCCTATTCTGAGTCAAGTTTCTTTAACTCATAGCAAATACCTGAGTATATAAAATAGTTCAATCGTAAATATTCAGGTTAAATTTGGCATAATAAAACCAAATAATTTAATCAAGAAAACAGGTAATACAATGCTTCAGGCATAAAATTAGACTTTTACCATCGCTAAATATCTTATTTAACAAAGGCTGTAACTTAAAAAAATGCTCTTCCAAAGTTGGCTCGTTTGGCATAATATTTAAAAAAAATTTGTTTAAATGATAAGTAGAATTAAAAAAATTTTATATAATATGTCTCTTTCATAAAAAAGATAATTTATGACAGAAAAAATGGTATCAAACCTATTAATTATGGACCCTGACTCCTAACCCTTGACTTCCAAGAAATAGTCTAGCTATTTGTAGCAAATATTGAGCAATTGGGTGCAATTATGATCCTGCTGAAAAGCCCAAAATTATGACTATAGGAAGCAATTTCCATCTACACTTGAGATTGCTTCCTTAGACTTAGCTACAGTTGCTGTCATGGACTGACAATAACTAATTAATGTAAATTAATATTATACTAAATTTCAAGAAATTTTTCTTAAACTTTTTTAATAACAGAAGAGGAGATATATTCTGTACTTATTACTTCCTACTACCTTAAATTTTAAGTTTCAGAAGGAGAAGATTGATTTAAAAAAGGAGTTAGATAAGCAACCAAGGCACCAATAAGAAAACCTACAACATTACGAGTCAATGGCAACCAATCTGAAGTTCTTGATACTACTGGACCAATTCCAAAAGCTATAAACAAAATTCCCCACAATGGAGAAAATATTAATGCCCACTGCCAAGAAAAAGCTTGGTTTGGTTTACGAGGTTGAGCTGCAAAGCCACAAATTACTCCGCCAATAACTGATGTAATCAAAGTTAAAATCCACTGCTCCTGTGGTAAACCAGGTACAACATTACAACCACCCTGGCGTAAACAAGTTTTGATAGATTCTAATGATTGAATAATAGATTGATCTTCACCTTGGTCTCGCACAAAAAATTGATTACCATATCGAGTTTGCAACTCTACCCAAAATGTCCTGGGAAGGAATTGGTAAAGACCGCGACCCACATTAAAATTAAGGATATTACCACCACGGGGGTCAGCTACTAACAATACACTTTTACTATCAAGTTCCCAAAAATCTTTAACTGCTCTACCAGGAGTACGGTCGAATTGAGTTAAAACTCTCAGTTTCCAACCAGTTTCTGTTTCAAATTTCTCTAAGTCTTTGGCTAGTAAGTTTTCTTGAATTTCTGTTAACGACCTGGCTAGGTCAATTATTGGTGTTTGCTCTTTAGGTAGTAAATCTGGATTGTTATAAGCTTGGGCAACTGTTGGAGTTAGAGCCAGAGTAGATAATGCCAGGAAGATTGATGCAATTGAGACAAAAAAACTTTTTGAAAAAAACTTTATCATTTTGTTTCTTTTTAATCCAAAAGGTGGACAATAGATACTTTAACTAAATAAAGAAATAAAAAAATTATATTTCTTTACAATTATTTACTTTAACTCACAATTTGATCAAGTGTGAAGTTAATTTTAAATATTTGTTAGACTTTTGACTTAATAGTATTCTCTTTTGTCAAAAAAAATTATAATGTGTTAAGGATCACAATCATCTATTTTTTCCGGTTAACAAAGCTGGAGTTACGAATATATTACTATCCGCCCCATCCAGAATCTATCTTGAAAGTCCTATTTCAAGCCAAAGTTACTCAACATAAAGCGTGGGGTTAAAATGTGACTTAATTTAACCAACTTGCTGTTAGAGCAACTGCTAAAGCATCAGCAGCATCATCTGGTTTAGGAATTTCCTCCAAATTTAATTCCCTTGCTACTGCTTGTTGCACATCATATTTATCTGCATTGCCATAACCTGTTACTGCTTGCTTAATTTGTGCGGGTGTAAACTCAATTAATGGAATTTCATTTTGTGCTAATGCCAATATTAAAATTCCTCTAGCTTGGGCAACTAAAATTGTATTACCCATACGATAAAAGAATAACTTTTCTGTAGCTGCCAAGTCTGGTTTAAAGTTATTTAGGATAGTATGTAAATCTTCATATATTGTGACGAGACGTTGCCCCATTTCTTGTTTTTTTGTAGTTTTAATTACCCCAAAATCAACCAGAGAAGTAGAATCTATTTTTTCTGTTTTTGAATTATAAATACACTTAATTAATCCAAATCCTAGTACCGCTAAACCTGGATCTAATCCGAGAATTAATTTTTCCATTTTTAGACTTTTAATTCTTATAGTAAATCTACTGTTGAGAGAGAACAGGATATAATTATAAATCTATTATCAAATATTACATTTTTCTAGTTTTTTCCCTACATAAGGAGGGGCAAAATTCCAAACATGAGAAGTAACTCTAAAGGGGAGATATCCGTAAAGGGCTAAAATTTTATATGTAATATTTTTATATCTTTTATATTTCTCGCCCCACCCTACTTACTTGATAAATATATCCTTGATAAATATATCAGCGATCGCCACGTTGTAAATTCCTGGTTTACCTACTAATTTTATCCAGATCTGTTTTTGAATGCTAAATCCAAATTTGCCATTACTATAGTTAATCCAAAATTAATTAATTTTATCTAAGTCTCTACAAGGTATATTTTTGATATCTTCTAAATCAAACCAGTACTTTTTTTCTCGCCCTACTAATGAAAGTAATATTCTTAGTATTTATTCGTCTGCTTATTTAAATTTATCAGATAACAGTAAGTTTTTTAAAGCTGTGTAATTTATTTATTTATCTATTGAATTATGGCGAGAAGTCATGGAAAAATTTAGATTAGGAGAAAAGATACAAGTCACAATAACAAATATGAATATACCAGTTCCTATCAATAGTTCATTAGCTTCTCTTGTATAATAATTTTTGCCATAATGTTGAGAAATACGTCTTACACCTCGAATATGTAAGGTAGTTATTTGAGTCAGAATTATTCGATAAAGCTGAGACATTTGAGAGATAATACTATTTTGAAAAAATTTATTTGTGCTGATAAGTTGATGATTAGTAAATGGTGGCTTTTTAATATTCCACTTTTGAATAAAATATAGACATTCTGTTCTTATCTAACTCCGAATTTGTGGAAACTTATTTATCTAAAATAAAAAATAATAACCCAAACAATAATAGCTGTAATAAACAAAAATATCACCATGAATAAATTATTTGAGATTCTTGTTTGCATTTGAAAAAATTTATTTGTGCTGATAAGTTGATGATTAGTAAATGGTGGCTTTTTAATATTCCACTTTTGAATAAAATATAGACATTCTGTTCTTATCTAACTCCGAATTTGTGGAGACTTATTTATCTAAAATAAAAAATAATAACCCAAACAATAATAGCTGTAATAAACAAAAATATCACCATGAATAAATTATTTGAGATTCTTGTTTGCATTTGAAAAAATTTATTTGTGCTGATAAGTTGATGATTAGTAAATGGTGGCTTTTTAATATTCCACTTTTGAATAAAATATAGACATTATGTTCTTATCTAACTCCGAATTTGTGGAAACTTATTTATCTAAAATAAAAAATAATAACCCAAACAATAATAGCTGTAATAAACAAAAATATCACCATGAATAAATTATTTGAGATTCTTGTTTGCATTTGAAAAAATTTATTTGTGCTGATAAGTTGATGATTAATAAATGGTGGTTTTTTAATATTCCACTTTTGAATAAAATATAGACATTCTGTTCTTTGCATAGCTAAAATAAAATCTTTCAAAGAGTACCATAAAATTTTAATTATCCCAGTAGATAGCTGCTCATAATTTTTTTTATCGGCAAACTCTGAATATAATCTAGTATCAGCCAATTCATTAGTTTTTTTTAAGTTGGTTTTTAATTCTTGTCAAGATTTCAAAAGCTCTCTTCAGTAGTTACTTAAAAACTCAAAAAAAGTAAACTTGCCACAATTAAATTGAAAAACTCCACCTTAGTATTGATAAATTAGTTACTTTCACAAAAGTAAAAATAAAAATATAAAAATTGATTTATATATATAAATAGTTTAATTAACAAAATTTTTATAGTAAATGGGTAGAAAAAGCATTAAATAGACTAAGCTTTTTCTTAACAACTAAATTTCTGATTTATCAGCAGAACTACCCAGAATAATAACTGCTAATTGCTCTATTAAAAGATTTAATATTTTGGATAATCTTAAAAATCACCCATGATTTAATTATATTCTGGAGAAGGTCTGATACAAATTTTTTCTACCAATTTCATCAACTTAGACTATATTACTTAATCTTAATAAGATTGTATGATTTCATTCTTGAGTATAATATTTAGCCATACTTAAAAAATTTGGTATTATAATTATTAAATATGACAGTATAACCAAATGTCTGTAATAATTCAAAAACTATAAATAATATCCAAAACTATTGCCCCAACTCCTCAAAACCCCTATTGCAAAAAGCGGTATAATTCTAGAAAACATAAAAATTTTAGTTTTATATGATTAATTTTTTGCCCTCGAAAAACCCGCTTTTCTAAATCCATTTTTCCCTAAAAAAACTAGACTACAATTATATTAATTCTCAAACTATTGTTCTACTTCTGCCAATCCAAAAACTCTATTAAAAACTTTTTTTACCTTATCACCAGAGTCAATACTTTCCAAAGGATCTTTTCGTAGTCGATGCCGTAAACACATAGTAATAACACGACCAACATCCTCAAGACTCACTTCTGTATTACCTTCAAAAGCAGCTAAAGCTTTTGCAGCACGATTAGTAACAATATCTCCCCGTAAACCATCTACATCTAACTCAGAACAAACCTGAGAAATTTTCACCCGTAAATCATGGTCAACTTCCACAAATGTCAACTTTTGTTGAGCATCTACAAGCTTATTTTGTAATTCTTCCTGTTGTGATGTATACTTTCCTAAAAACCCTTGAGGATTTTGATCAAAAGCTGAACGTTGTTCAACAATTTCAACTCTTAAGATAGGATCTTTGACAGTTCGGATTTCAGCATGCATTCCAAATCTGTCCAGTAACTGAGGTCGTAATTCCCCTTCTTCTGGGTTTCCCGAACCTACAAGGACAAAACGAGCCGGATGGCGTATAGAAATACCTTCTCTTTCCACAGTATTCCAGCCACTTGCCGCCGAGTCAAGCAAGACATCAACTAAGTGGTCATCCAAAAGGTTGACCTCGTCAACATACAAAATACCACGGTTAGCCTTTGCGAGTAAACCTGGTTCAAAAGCTTTCACCCCTTCTGATAAAGCTTTTTCAATATCAATAGTACCACATACCCGATCCTCCGTCGCCCCCAATGGTAAGTCCACCATTTGGACTTTTCTTGTAAAAATCGGAATTTCTTCCTGCTTTACTAATCTATCTCGCACAGAATCACTCATCAAATCTGGGTCATAAGGATCACTATTAAAAGGGTCATCAACAACAATTTTAATTTCTGGCAACAGGTCAGCTAATGCACGGATAGTGGTAGATTTACCTGTACCCCGATCACCCATGATCATTACCCCCCCTATTTTGGGGTCAATTACATTTAATAGTAAGGCCAGTTTCATTTCTTCCTGACCGACAATGGCGGTGAAAGGGAAAACAGCTCTACTTCTTGGAACGGCTGATTTCACAGATGTATTTACATTTTTATTGGCTTTAACGGTTGAACTCACTGTATACTCTAAATTATAATTACTAATTTTTATCTCAATTTTGGTTGAAAACCCGTGCTCACCGAAACAGGAGTCTTGGGATGAAAACCAATCAATATTGCAATTTAACACTTCAAATGTTATACCTTGAAGAGTTAATCAGCAAGTAATAAATACTTAAAAAGGAGTACGCTCCATCAGTAAACTAGGCTTTAAACCTAATATTTCAGTAAAAATATTTTGGGACTTGAACTCGCAGTATCATTCTCTGGAGCAACTATAAGACTATCTGAGAATACATCTTAAATATTAGGTAATATTAGGTGCTCAAGAAATAGAAAGTCTTTGTCAATCATGTCAGAGAATATCGCTATGTTTGAATACAGCAGCATGATGTCAATTGGAATATTGATGCATAAGTAAACTAGATAACCCCTGCGACTATTACTATAGAATCAATTGTGACAAAACCTGTAATACCAATTTTAAAAATGCCTGAATTCAGAATAGTTCTCTAGATGGTAAGAATTTTATGATACTTAGTTTGTAATATTCTTTTTTCAAAATGTTATAAAATATAGACTCTACCCAAATAAGCAACAGAAAATCTCTTAAGGTGCCGAGTTCCATAGTTCTCTATAATTGCGGAAGCATAAAGTAACTATAGACAAGAAAGGGTGAGAGAAATTCCTCGTTATTGGATTGAGTGAGGGGTAGTTCAATGCAAATGTTCATTTTCAGTATTAATTAAAATTATGATCAGCCAAACTTCCACTCCTGTGATTGTTTGTGGAGCTGCAGGTAAGATGGGTCGTGAAGTAATAAAAACTGTAGCAAATGCTAGTGATATGACTCTGTTGGGCGCAATAGAGTGCCAGCCAGAGTATATCGGTCAAGATATTGGTGAGCTAATTGGTTCTGGTCCACTAGAAGTACCAATTCTAAATGATTTGCAGGGAATTTTAGTAATGGCAGCTCAAGAGAAACAACCTGCCGTAATGGTTGATTTTACTCACCCAGATAGCGTTTATGAAAATGTGCGTTCTGCTATTGCTTATGGAGTCAGACCTGTGGTCGGAACGACAGGTCTGAGTCAAGAGCAAATTCAAGATTTGGCCGAGTTTGCTGAAAAAGCCAGTATTGGTACGTTAATAATTCCCAACTTTTCTATTGGTATGGTTTTGCTCCAACAAGCAGCGATCGCTGCTTCCAAGCATTTTGATCATGTAGAGATTATTGAGTTGCACCACAATCAAAAAGCTGACGCCCCTAGTGGCACTGCCATTAAAACAGCACAGATGTTATCTGAACTAGGAAAAACTTACAATGTACCTAATGTAGAAGAAACAGAGAAAATAGAAGGGGCCAGAGGTTGTTTAGCAGAAGAAGGAATTCGTATCCATAGTGTACGTTTACCAGGTTTAATTGCTCATCAAGAAGTAATATTTGGGGGACCTGGCCAAATTTACACTTTACGACACGATACAACAGATAGGTCTTGCTATATGCCTGGAGTTTTGTTAGCCATTCGTAAAGTCCAATCTTTAACCAAGCTCATTTATGGTTTAGAGAAGATACTTTAGTTTTAAGAAGAACTGCTGCGTCTACTACGTCTACTTTGGCGGGAACGAGTTGAGATATCGTATTCTAGCACTGCACCTATTGCAAATAGAATTGCAGTAAATACAAAAAATACCTCTAAGAGACCTCCACTTTCATATTCTCCAGTAGTCTGGGAATCTGCCCACTTAAAATACATATCAGCAATGTATAATGAAAATGTAGCGCCAGCAATCATCCGCCAGGACTGAGAAAAACGTCCTCCCCAAAAGGCTAGAAGTAGAGCTGTGGCAATAATTAGTAGAAATACATCGGCAATAATATAGAATAAATTCAACCAAAAAGAAAAAGGTTCTAATTTATTATCTAGAGCAAGTACCCAAGATGGAGCTAATTGAGCTGATTCTATTTTTATTGTATCTAGCTCTTCCAAAACCGTAGTATCTGGCGTAGACAATAAACCAAAAAACGAAGGGTCAGCTACAAAAATAGCCAAAAGAACTCCTCCAGCCGCGACTAAAGCCAAAACCACCCACTGCCAAAATTCTAAATTTAGCTTTTTGGCAGTTATAGCTAGAGTCATACCCCAAGCTAAAAATATGTAGGAAAAAACGTAAAATATATCTGCTAATGATACATCTGGGTCCAGTTCCCAGATTAATTCCCAGCAGCCAAACACAAGACCACCAATAAAGTAAAATAATAATCCTAAACTAATACCAATCCAAACATTTCGGCCACTAACCATTTGAGGACTTTGCCAATTTCTGAAGCTAATTATAGTGGCTATTAAGTAAGCCCCTAGTTCAAATATATAGGTGCCAACAGAGTACCAGGATGGTAATTCTTCTCCTGGTAGAGGTACACTAAATAATAGAAAAAATAATAGGGCTAATACACCCCAAATAAGACCTGTCATTACAATAATCTGAGCTGAAAATAAGGACTTAGTAAGAGTAGATAATTTTTTTGAAGTGCTGCTCATAGAAATATTCTGATTAAGGGCTACTGTCAACAAACATTTTATCCCTATTACTCAACAATTGTAGTTTTATTTCCTCCGAGATAAAGATAATTTTAATCAGGATAAAATAGATTTATAAATTAGAAAAAATAATTCTAGGTTTAAGGGTTTATAGGCTATAAAATATACAGTATTTTTGCCTTTTAACATTAATTAAATCTGCTGTTTAAACATCTCAATACTATCTCATATAATTTTATCAGCTAATGATTGATTACTATTCGACCAACTTTATTAATATCATTATCCATTTGACTCTTCTCCTCTTCTATAATCCCAGCTAGTTAATTTTAGCAAAATCCTTAAAGTTAATTTTTTTATAGTTGACATTTGTTTTTTTATATCAAGGAATTATTCATTTAATCTGTAACAACATCATAACAAGATAATTATGATTCAATTATAGTTCTTAGTATTAGTTGTGCTGCTGCGTGAATTTAGCGAAAAATTTGGTAAAAAGTAAAGTCTCGCCCGCCCATCCGGTGACTTTTTAGTTGTTTTTTTTGAATAGAGCTTTTATTTTGTCATTATTTATAACCTAATCGCAGAGGGGCAGTTCCAGACAAAAAATAGATCTGGAGATAAGGGATTTAACTAGCATCAAGTTTTATGATCATGACAAGAAATTATAGAGGCCTATAAAACCTCAACCCAACCTTGAGTTTGTCGTCATAAGAATATTCCCCATGGTTAACAGTCAAAGAAGAACTCAAAACTCTATAGTAATTATTATTTCTGTATACTTTTACAAAGTTAAATTAGTCCATGGCAAAACTCACTTTAAAAGATAATTCTCCAACACAATATAAGCTAAATTTACTTAATTTTTTGTGCTATTCACATAAGAATATCGGAATGACAACTAATTTAGTATTTATACAGACTAAAATTTCCTGAAAAATATACATTTTTCTGAAGTGAAATATCCTTATTAATTTTATCAAAAAATAGAAATATTTTAGTATTTATACCAGTTTATGTATGCAAAAACAAAACGGATAGCTAGTTTTCATCTCTACTCTAAAACAGACATTGCTCTCAAACTAACTTTTTAATAATACTTAATTATGTAGTAAAGCTATACTTAGGTTAACCTCCATATTTATTTAATTTTCATCAAAAACTCAGACTTCTGTTCACAAGCTATAAAGATTACTTAATTGCCCATTGTTTACCTTCAGGGAATTGATTTAGCCAATTCATAAACTGAGTTCTTTCAGGAGTATCCATAGGTTCTAGGATTTCGTCAATACCTTCAGCAAAATTGGAATTGCCAAAATATTCTTCCCCTAAACGATAGACCTCTTGTAGTAAAGTATAAAGATGACCTTCTTGCCAGGAAGGTAGTCGTAATTTTGTCAGAGGATCGTCTATTAATAAAGCTTTAATTGCATTCGCAGAATCTGCATCAGGAAAATTTTTCCCTTGAAGGACTTTACTAAAATCCTTTTGAAAAGATTTAGCCTGTCTATTGCCCAATAAATCTTCTACATCAAAGTAAACTGCTTGTACCAACAACAAACAACCCTGAATACAAGCAGAAGCAACAGTTTTATTCTCTTTTGAGTCTTCGCTAGCAAGTTGATCCAAGCGAATTTTAACCCAAACACTATATCGCTCAGGCTCTTCTAGCAAAACACAAGCCTTACCATGATTATCTGTTAAATCTCGCCAGAAAGCTCTCGCTTCTTCCGCTTGTTCTCCCTTAAAAACATTGATTAAGCGAAACGTTTGTCCTTGATAACTAAGAATAGGGATCTTTTGATCCCGCTTTGGGTGTGTAATACTTGTAATTTCAACATCTTGCCTTTTGAGAATAAACATGACACTTTAATTAGACTCTCATCATTATCTATTATCTGGGGTATCTTGGTGTAATTGTAATTCTTTCTCAGAAACGACTCTACAAAAATCAGTACACAATCTATGATTATTTGACTGACTATATATTTCTTTTTCTGTTTTATTCTGGCAGTGTGGGGAGTCATTACTCCAAAGGCTTTATAAGCGATCGCCTTAGTGGAGCACAAATCTAGCCCTCTGCTATAGCTAGATTTTTATCTGCATTTAAGTCTATATTGCAACTGAAACCCCATACCCTATTTCCTACTTACTCTTCTCTACCGAAGGTAGATATAAGAACATTAGGCAATAGGCTAGAATTTAGAATATTCAACTTCAAGATAGAGAATAACATTTTTATTATGCCCAAATTAATGAGAGTTGATATAACTAGAGTGTGAAAATCTTAAATTTTATAGTCTAGAAACGAGCAATGCTTGTGGACATATCAATATCTGTCACTTAAGTTACAGCTTAGTTGATAAGTTAGTTGCATAAAGCTATAATTGAATATTATATCTATGATTAATGGGAGTAGAAGAATGTCAGTTCCTGGGGACTAATATTTGATTAATTGAATATCAATTATGGACTTGCCTATTTCGTGACATTCTTTTTTTTGACAGTTGGTATTATAAATATTTTATGCTATAGTCAATAGACAATAATTAGATATGGAAAAGTATTTAGTTAATTTCAATGATTGTAGCTAGATTAAAAATCTTCCAAGTAAATAAAATTTTTATTTCTTTTTCTTTAAAGCCGATATTATCTTAACCAAGTATAATAACTTTAAGATATAGTATTAATATATTAAATAATGATTGGGTGCGTAACTCAGTTGGATAGAGTAGCGACCTTCTAAGTCGCGAGTCGCAGGTTCGAATCCTGCCGCACCCGTAAATGAAAATTAAAAGTGCAATAGTTTTTATCTCTATCTATCAAAAAAAACTATTGTTTAGAGCTTTTCATCAATGATATATAGATCAGGACTTATGCAATTAATTATAGTAATTGTAGTTAGAAGGTCTAGAATAATGGTGTAATTATAGGCCACACATAGTATTAATGTCTAAGTCCTATAGAGGTTGATATTATTATGTAGTATTTTTATGCTACGTAACATATGAAGCTTTGTCTAAATTCTAATTTTCTCCAAAATTCTCAACAAAGATCTACAAAATATCTAGTGTCTAGTTGCAAAAGTTAATTTATTTACACAAATGTTAATAGTCATATTTTTCTGGATATATAAGAAAACAATTGAGGACTTCACAGATTCATAACTTGTTAGAGTCGATGGGGCGTATAATTAACCACCCGCACCTCTTATTCAAAAGCTATCGTGGGACTTTAACTCAATAGGCTACATAGATGATCTTAACCTTCATTGGCACAATTATAGACCTGTTAATTCCTTAATTCTGGTTTATAATTATTAAATTTTTAATCTAGTCTTAGACTTAAATTCTACAGAATCTACTAATGATTACTAATGATAAAGTTCTTCTGAAAATCGACAAATATTATTAGGACATAATACTCTAAAAATTATCTAGGAAAGATATGACTGCTCCTTTGTAGAATTGAATATTTACCACCATATCTTTTGTAGGATTGAATATTTAACACCATATTCTTCTAACTTCAATGAAATAGAAAATTATTGTTTTCTCATTAAAAACCGAGTGAGTAGGGACACCCTGATGCAATGTCCATAGGAAAGAACAATAGAATATTTACTAAAGTGATAAAACTTTATACTTCACCCGCCTCAGAAAATTCTGTAAGTGAATTAGCATTAACGGTACTTTGACATTTTTATAGTACGAAAATGACTTCAAAGGGTTGAGGGAAAAAAGAAATATGCAGCTATTGTTAAACATGGCTCAAACAAAATACAAAAATGGAAACAAGTAGATGAGAATATCAAACAATTGCTATGTAATGGTTTGATACTATTTTGTACTTATGTGTTGCTAAAGTATAATTAATTATAAAGTCTAACTCAATCCTTTAATTACAGGGTGAAAATAAAAGGCCAGTCCTAAAATAGTATAAGCTGCTAATAATAAAACCCCTTCTAACCAGTCAGAACGACCATCAGAACTGACAGAATTAGCAATTAATACTGCTACTACTACTGCTACTAATTCAAAAGGATTAAAATTCAAATCCATTGGTTGACCTAGCAATGAACCAGTCAGAATTAATACAGGTGCCACAAATAACGCAATTTGTAAACTAGAGCCAACTGCTACACTTACAGATAAATCCATTTTATTTTTCATGGCAACAGTTACTGCTGTAGCGTGTTCGGCAGCATTACCAATAATTGGTACTACAATTACACCAGTAAATAAAGCAGTTAATCCTAATGCAGAAGTAGCTTCTTCTAAAGAATCAACCAATAATTCTGATTCAAATGCTACTGTTAAAGTTGCTATTAATAACACTAAAATCCACAGTAACAAATTAGGTTTATGTTCGGCATTTTCTTCTGATTCACTATCAGAATCTAAATCCTGTGATTCACTTCCTACTATACCAACTTCATATAAGTAAGAGTGAGTTTTCATGGAAAATAGTAAGGTAAGTATATAAACAGTAATTAATACTATTCCTACTGCGACAGACAAATTTTGCATTGTATTACTACTAATACCATTGGAAGTAGCATTCACTGCTGTTGGTACTAGAATAGCAATTACAGCTAAATTCATTGCTGAAGCATTTAAGCGAGCTACTACTGACTGAAATTTTTGTTCTTTGAAACGGAGTCCACCTAAAAACATTGAGAGGCCCATTACTAACAATAAGTTACCAATTATAGAACCGGTAATGCTTGCTTTAACTACCCTTACTAAACCAGCATTTAAAGCAATAATACCGATAATTAATTCTGTAGCATTACCAAATGTAGCATTTAATAAACCACCTAAGTTAGGACCTAGAACGACTGCAATTTCTTCCGTTGCTGTACCCATCCAACCTGCCAAAGGAATAATTGCTATAGCAGATGTAATAAAAATTACTGATGAACCCAATTCCATAGCATTAGCAGCTATTGAAATAGGAACAAATACTAATAAAATTGAAATTATTGTTTGTGCGTTTAGCATAAGTGTAAATTGGGGGTTTGGTAAATCATAGTTACGCCAAAATTAACAGACATAATTGATAAGTTTTCAGGTCATTTGCCTATCTGCAATTTATTCCCGAATTATATTCTCAATTAGAGGTTGCCACAAGTCTTGATTTTTGTCTATATCATTAGAGAAGGCAAAACAAATTAATATATCGAATCAATGAACGTTATTGAGAAATTATGCAAAAATATTCTCAAAGGAAGATAACTCAAGAATTTAGCCTGATTTTAGATGTTTCGGATCTGAGAAAAAGTGGTAATTTGACTATAGGAGTAGGTAGGCACTACAGTGGATGCCAGTCTAAACTACTCCTCTTGAGAGTAGGGCTGTTTTATTTGAGGTTTAAAATCAATAAAAGAAATAGTTTGACTTTGTATTAAAATTTTTACTAGTCAACTATTTTTTTATAAAATTATGTATATAAATATTTTAATTAAAAATATTCAAAAAACAATTATTTACGCAAATATTAAGGGTAAAATATATTAATTATGGTTAATATTAGTAATTACTATTTGTTGCATTTTTTGTTGATATACATAATATAGTGTTATCGGATATTTTGCCTTAGCTAATCAATTAATGGTTATATAAGTTTTTAATATTTATCCTGAAAGAGTACCATCATATTCAACAATAATAAGATAAATAAAAAGGAAATTTTTCTTGAGTTACTTTAGAACTTTGATGAATCGGCAAGACAATTATCTACGGGTGATTTATTTTTGCAAAAGTGGGTGGATTTTGATGGCAAAATTTGACGAAACACTATTAATAATTTTAACAAAATTTAACAAAAGTTTGTTTCAATAATTTCATTATTTAATCAAGATAGTAGGATTGTTTTGTACTTAAAATTATTGGCAAATAAAAAGTGTTTATAAATTTATCAATATTAAGGCATTTATAAGTAATTTTTTACTAAATAATAGTTTTTCTGTGATAGATTCTTTACATTTCTAGAAAAAGACTACTGAATTAATTGCAAAAAAAATAATGATTATTTAATTGCTGTAAAAAAAATAAACTTACTTTATATTAATAGATAGAATAGGTAAGTAATAATTTAAATTAAATTGACGTTTTCCATAAAAAAATAATAGTCATTTTCTAAAAATAGGAATAATAATTTCAGTTTTTATACCTGCACATTATATGGTTAATGGTTGGAAAAATGTTCAACATTTTATTCAAGTATAAAGAGGTTAATTGAGAGGTAAAAAATATTATGAATAAACTGTTTTTGATATAAGTAGTACGACAAAAAGGGTGAGTTTTTTTTATTTTACAATTAGAAAAATTGAAAAATATAAAATAAATTGTATTGGGTCAAAGATGTAATTTTTAAGTAGCCTCCATCTTCGATTTATGAACATTAAGCAGAAATAAATATATCTATTTTAAAAAACTATTGCTATTAATTTTAATAAGATTAATTGTTTTTTTAGTAACTGAAGCCCAAAGACGGCTTAATAGCAAATGTTTCAAAGTTTTGGTTTGATTGAAATGAAACAGCCATGCCCCTCTTTAGACCAGGACCTTTTCATTTTCAGCGATCGCCAAAAAAATCAAAGCACTATTTTTTTATTTTATCAAAAAAGATGGCTTAACTTTTATTTTAAATACATCATGATTAATACTACATTTGAGAGGTTGAAAAAATTCAAGTAATTCCAGAAAAATTAGGGTAAAAGACATAAAATTTGGGTAGTCTTAAGCATTATAGTCTTAAGTCTTTTAACCGGAAATTGTAGTTATAAATAAATAGAAATGTTTAGTTATAACAATCATGAGTAACTAATAAATATATTAAGTATACCCTCAAAAAAATTACCTCCATGTAGTACTCTTAGGAGAGTTATGATAGGAGTAAAAGAATCAGAGATACAATTTTTTTATGAAATAATATCAGCTAATTATTCATAGTATCAAGAGGATTGGATTGCAGTTGATGGTAAAAGCTTAAAAAATACTTTTATCAATTATGAACAAAACGGACAAAATATGTTAGTAATACTATCAGGGCTTAGTCTGGAAACAAAACTAATTGGGGTTTCAAAAACATTTGAGAATAAAAAAAGTTAATAAATTAAGCAAGTGCAAAAGCTGATAAGAGATAGCGGTTTATAGAATAAGACATTTACTTTGTATGCACTTCATTGCAATAAACAAACAACTCAGATAGTAATTGAAAGTAAAAATGATTATTTAACTACAGTAAAAGCTAACCAAATCAATTTATTTAATCGCTTAAAATACTTAGCAAAAGTAGAGGACTCTATCAGTAGATATCAAGAAATATAAAAAATTCATGGGCGCCAAATAAAGAAAAAATTTAGGATCTTTAAAGCCGAAAATATTAAACATAAAAATTATCTTCATATTCAAAGCTTTATAAAGGCAAAAAGAACAGGAATAATAGAAAAGCAAAAGTCTGAAGAAACTTTTTATTATTTTAGTAGTAAAGTATTACTCTCAAAAAAAAAAAGAAAACATTTAGGATATTTAAAGCCGAAAATATTAAACATAAAAATTATCTTCATATTCAAAGCTTTATAAAGACAGAAATAACAGGACTAACAGAAAAGCAAAAGTCTGAAGAAACTTTTTATTATTTTAGTAGTAAAGTATTACTCTCAAAAAAAAAGAAAACATTTAGGATATTTAAAGCCGAAAATATTAAACATAAAAATTATCTTCATATTCAAAGCTTTATAAAGACAGAAATAACAGGACTAACAGAAAAGCAAAAGTCTGAAGAAACTTTTTATTATTTTAGTAGTAAAGTATTACTCTCAAAAAAAAAGAAAACATTTAGGATATTTAAAGCCGAAAATATTAAACATAAAAATTATCTTCATATTCAAAGCTTTATAAAGGTAGAGAGAACAGGACTAACAGAAAATAAAAAGTCTGAATAAACTTTTTATTATTTTAGTAGTAAAGTGTTACTCTCAAAAAAAAAGAACACATTTAAGATATTTAAAGCCGAAAATATTAAACATAAAAATTATCTTCATATTCAAAGCTTTATAAAGGTAGAGAGAACAGGACTAACAGAAAATAAAAAGTCTGAATAAACTTTTTATTATTTTAGTAGTAAAGTGTTACTCTCAAAAAAAAAAGAACACATTTAGGATATTTAAAGCCGAAAATATTAAATATAAAAATTATCTTCATATTCAAAGCTTTATAAAGGCAGAAATAACAGGAATAACAGAAAATAAAAAGTCTGAATAAACTTTGTATTATTTTAGTAGTAAAGTATTAATCTCAAAAAAAATTGCTTCAAAAATCAGAGGACATTGGTTAATAGAAAATCAATTACATTGGGTAAAAGATGTGATTTTTAATGAAGATAAATCAAAGATAAGATAACTACAAGTAGCTCGAAATCTTTCACTTTTGTACACAATAATTATGAATGTTTACCGAAGTTTTGGTTTTGACTCAATAAAACAAGGAATATATTGGTCAGGAAATAATTGGAAAAAAAAATTAGCATTCTCTACTTAAATAGACAATAAAAATATATTTTTAGTAAAAAAAATTATATAAAAAATGATAATAAAACGATAATATATTCTTTAAAAAGCATTAGATTAAGTTTTTAATATCAAAAAATAGAGAAAGTTATTGTCTGAAAAAATCAGAATCAATTAAATTATAATCGAGCAATATTAGGAAGGAAAAACATGACTTTTCTTCAAAAATTGACTACTAATTTTGGAGAATGAAAAAGCCCTGCTCTTTAGAGTGGGTTAGGCTCGCTGTGAAAAACTATTATCAGGCCTATAGCTAGGTTGTTTCCCGGTGTCTAACAGCCGGGAAGGATGTCAAGGCCGTTTTGAAGTTCTAGAAGTACAAAGTTTTACTAGTTTATGGAACAGAGATTAATATTAAACTGCAACTCACTATACTTAAAAGTATTGTCAACCGAGTCTTTAAAATCCCTGCATTACTATTGCTGAGGGTTCTTGCTAATAGCTAAATCCTTACAAATTAACTAAGATCGACACCTAAAAATTTATCTAGAAGTTTGGTTCGCCATACATAGCGTAGTAATAAACACCAAACTAAAGCTACCCAAATAATCACAAGATAATCATGAGTACTTAGTAAAGATAGTTCAAAAAATTGACGTAGAGGGGGAACGGCTAAAATGACTATATAAACTCCTAGTAAAGCTAAGGCAACAAAAGTATACCGCCAGTCACCACTGTAAGTTTCTCCACCTACCCAAGCTTTTGTTGGAGGCTTCAAAAAAGGTACTAACAATAGACCACATAAAATCATAATTGTAACTAGGGCACTACGAGGAACAGAAAGAAACTCATTAACTTGGTCAAGGTCGATAACTAACTCATTTCCTGAAAATGGTATTGCTAAATAGGTTAGATAAACTAGTAAGGCTACAAGAGTAAGACTAAAAGTAGCAGGTAAAGTAAAATGTAGTAAGGAGCGTATCATACTACGTCGAGGTAAGATTCCTGGTTTAGCCCATATTGGAATACAAAAAGTAGGAAATCCTACTGATATTAGAGTTACAACTGCACTATGTTTATTTAATAGTGGGAAAGTACCACCGATAAATCCACCAATAAATCCTGTAGAAAAAATTAATATACTTACGCAGAATACCCTAATCATAAATAATTTCAATACATCTTGTATACTATTACGAATACGTTGTCCTTCCAAAAAAGTATGGGGCAAAGAGGCGAAAGAATTATTCAACAGGACAATATCTGCCACGCTACGAGTCGCCTTACTACCTCCTTCCATAGCGATCGCTAAATTAGCTTCTTTCAAAGATAGAACATCATTAACCCCATCTCCGATCATAGCTACATAATGACCTTGTTTCTTAAAACTATGGATCAGTTTAGCTTTTTGCTTAGGAGTGACAGAGCCAAAAATTGTCTTAGATTTTGCTGCTTGAATAAACTGATCTTCGTCTAGTTTAGCTAATTCAGAACCAGAAATAACTTGGATATTAGAACTAAGTCCTGCTTGCAAGGCCAAAGTAGCTACAGTCTGAGGATTATCTCCAGAAATCACTTTGATTTTTATTCCTACTTTTGAAAAACCTTCTATAGTCTCACGAGCTTCCGGCCTAAGTTCATCTTGAAAGCTAATAATTCCCAAGGGAAAAAGTTCTGTAGGTAATTGTAGTTTTTCTAAATCCTGGTCTAAGCTACTGATGTTGGGGTTATAGGCAAATAAAAGTACCCGGAATCCCTTTTGTGCTAATTTTTGAATTTGCTGAGTAAATTTCCTACTAAGAGGTGTAACTTCAGCTAATATTTCTGGAGCACCTAGAATGTATGTCCCAGATGGTGAATTTTGCTCTTCAGTGGCAAAGCTCATACCACTCCATTTACGAGCTGAAGCAAAAGGAATTTCAAAGGTTAGAGAACGTTTAGGTCTTGGAAAGACCCTTTCTAGAGCTTCAATAGTTTTATTTTTAGAAGTGGTACTGGCTGCATATTCACCTAATATATTTTCCAACTTGATTTCATCAATTCCTATGGGATAAATTGCTTGTAAACTAATATGGTTAGTGGTTAACGTTCCAGTTTTGTCCAAACATAAAATATCTACATTACTTAATGATTCAACAGCATTAGCTTGCTGAATTAGGACTTCCTGTCCCACCATTTTGACTGCACCCAAAGCATAAGCAAGAGTGATGGCTAAATAAAGTCCACTTGGTACTAAGCCAGCAATTACAGCAGCATATTGAACAGTGTCAACAAATTTATAAAATCCAAAGTACCAGTTAATGGAAACTAGTATCCAGAGAAAGCATGATAAGAGTAAAAAGACTCTGATGACTAGGTTAATTTCCTGTTGGAGAGGGGTATAAATTTGGCGAAATGCTCTGGCACTAACTGTTAGTTGATAGGCAAAACTTTCGGTTCCTACTTTTTGGGCTTCATAATGAGCAGTGCCACTGACACAGAAACTACCAGAATAAACTGGCTGGCCTGCTTGTTTAGGAACTAGATCTGATTCTCCTGTTAGGAGTGATTCGTCTACTTCTATTTGCCCTTTTCCTACTACTTGTCCATCTACTACTATTTGATCTCCAGAATGGACTACTAATATATCTCCTACGACGATCTCACTGGGATCTATGTTTTGTTGTTTAGTTTCTCTTATAACTGTAGCTAATGGTCTAGCTAATAAGGCAATTTGATCTAATTTTTGTTTCGCCCATATTTCTTGGCAAACACTGACTATGACACCACCTAAAATAACGATGATTACCAGGAAAGCATCACCATAACGAGAAAGAGAAATTAAAACTAGGCTAATGCTAAGGAAAACGGTATTAATAAAGGTAAATAAGTTTTCTTTTAATATCTGGCGGTAGGAGCGACTTGTGTCTAGTTTGATATTATTTCCTCGACCGACAGCACGAAGATTTATGACTTGGTCTTTTGTGAGACCGTGAATAATTGAGGTATTGTGAATATTTTGGCGATCATTCATGGCATTTGGACTTAAGATCAAAAAGTTTGTTTAATACCAATTATGAAAAATATTGCTACATTATTTTTTTTTGTCTTCAAAAAACTTAATTGTAGGCATTGTTTGATGATGAAAAGTAATATTACTAATTTATAGAGAAGTTATAAGTAAGGTTAAGTTTGATAAATAACCTTTGGCTTTTTTGATTATGATCAACTTTAGTGATATAGAAATTTTAAATGATTCGATTTAGATTTGCTATATTTTGATAGTATTAGATTATGTCTAATTTGATTCTGGGGGTAACAAGCAAGTTATAAAGTAGATATAATAATAATTTGAGATAATAAATTGAATAATAATTTCATAAAATAAAAGAAAGCTTATTAAGAATGGGGTCGTGGCGATCACCAATTTACTAAGTGCTAAAGTGCTACTACCTGATTTGATTACTTTTTCATTTAAGCTAATGGGTAAAATAGTTAAAAATATAATCAAATAAAAGATAATTTGTAAACTTTACCAAAGTCTTGATTACTTAGTTTTTAGCAATTACTTCTTTCCCGCTAGAAGATTAACAATTATATAGTATAAATATTACAAAAGCCAATTAGAGCAGCAAAACAATAAAACCTTTATCCGATATAATGGTTCAATGATCGCGATCTTAGACACTGAATTACGGCAAAAACTATAATACAAACCTCAAAAAGAATATTTATCAGAACAATTATTGGTAGTTATTTATACTTTAATCTAGCCATGCTAAAAGTACGCAAATATGCCGAATTATATTTTGCATTTGTTCAGGTGTCTGAAGTTGATTAAATTGAAAAAAATTTTCTAATTTATCTTAAAATTGTTGAATATTTATATCCCAGGAAAGGTGATGCAACAGTTTAAGTCTTAAAATATGAATAATATATTCAACTCAATTAAAATTAGGAAAATATGTTGGAGTATGAATAAAATCTACAACAATTTTATCTGAATATTTGAGCATTAATGAGATGAAATTTTAATTGAGATTTCATTTTATTTTTATCTGTCGAGTCCAGATCTAAAATAATAGTCAATTTATCAAATCATTCTGTTAAAAAATCTTGATCTCATTGTAAAAAGTAATCCGAAACTTCCTCTGCTTTAGATTTTTCTTTTAATTTTAAAGACTCTTGAGCTGTAAAGGCATCAACTGAAATCATTCCATTCAGTTTATTTCTACATCCCTTCTCATTACTGGCTACTTCAGGACCTGTCTTTTTTTTTGCCTATCCGTAAAAAATGCTTGGGCGCTCATAAACAGCAAATTCATCAAAAAATACTATTTTTTCTTTCTTTATTTTAGATACCAATTTTTTGAGACTTAAAATAAATATCTTTTACTGTTATTGGCTGGTATTAGGATAATTTCTATGGGCTTTTTGAGCTGATAAATTTAATTCATTGAAAATTTCATATATTCTTGTTGTTTTCAGTTTTACTCCCCATCTTAATTCAATAACATTACTAATAATTTTACCAGCTCCATTTGTTTCTATCTACCACATAATCTCTGGGTAATTCTTCCAGTATCATTATTTTTAATTCCTATTTCTGTTTTATATTTAATCTTGATGATACTTGGTGAGTGATTAGTTATATTAAATTCTTTAACCCTCCTTCTAAAAATTTATCTATCCAAGTAGATAAAGTTTGGTAATGACAATCTAATAAATCTGATACTTCTGCTCTATTTTTTCCTTCATACAAGTATTTAATTGCCAATAATCTTTTCCTTAAATATTCTTTTTGACACTTGTAGTAAAATTATGACCACAATTCTAAATATAATTGGCGATCGCCTAACCTAAAAGTTCTATTCCCTAAAGATTTAATCATGATTCATTCCTTATTATTTATCACGTAATATATATTATTACATAATAGGTAATTTTCTAGCGGGAAGAGAGTAATGCAATCAGATGAATATAAAATAGAAATTAGGGCGTTCCTGAAGCGCGGGCATGATTTTGAAAAAGATCGATCACCAATATAAGTCATACCAATTTTATTAGCCTACATTACTTAATCTTGGTAAGATTATATAATTTCATTATTGAGTATGATGTGTAGCTATACTCAAGTAAATTGACATTAAAATTATTCGGATATAATGTAATTATATTGAATTAAATAATACTGTAAACAGATGTTTTTACTGAGGATATAAACTGTGGACGAAAAAAATCTAATTCCTCAAAGCGGCCTTGATTTAATTAAGGAATTTGAGGGGTATGGGAAAGAACTTCCTGATGGCCGAGCACAAGCGTATGCCGATCCCATTTATGGGTGGGAAGTTGCTACAATTGGCTATGGAACTACCAAGTATCCCAATGGTGTGCGACTCGTTGGCCATTAAACCTTGAACTAGGATATAAATGGCTGTTCCAAGTCAACACATGAGGATAATCTCGACTTGTGAATAACTCTTATGACCTTGTAGGTGAGATTCCTACTGCCTTGTTGTTGGGTTGACAGCGTAGGCCACAGGGTAGAGACTGAACATCAATCCCTGAAGCTGGTCTAAACGAGGTCAAAGCTTTAACTACCAAATAAGTGAGACTTCTAGCAAAGACTGACAAGTAGACGAACAGAAAGGTAATAAAACTCTCGTCAGATATGACCATTCCAAAGGTAGTTATGGAATGTAGGACGAATGTCAGAGGGTCTATGGATAACAATATGCCATTGTTGTTATCAAACAACTGTAAAGAACCCTCCGGGAGATTTTACCCTACTAAATCAGTCGTAACAAAGGCATAAGGGAACGAGGAAACCTCTTTAAGACACCTAAGTATATAGGTCGATAACTTAGGAAGCCATTCAAGGTAAATCTACGCAAAAAAATCGTAGGTCTTAGGGAGAGTAGGATTGGGTAAAAAGTATAATTAGCAGACGTACCCACTGTTAAACGTGATGTAAGGTAACAATTAGTGATGAATAAGGCTAAAACACTAAAAAGACATAATGGTAATTCTAAACCATTTTTAAGTGTGGCATGGGATACAGACGATACACCTTTACAATTCTCTGTATGTCTCAATCTTAAGTGGCAAGACATAGAATGCAAGGGTGTTCTCAAGAATGTATTTAAGTTGCAAAAGTTAATTTACAGAACATCCAGCTGTGGCGAAATCCCCAATATGCCTGAATACTAAAAACTTCTGACTTCTAGTTATTACCCTAGGTTACTAGCTGTTTGGTGCGTGATACAGGACAAACAAGATCAAAAAACTGCTGGAGTGGATGGGATGAAAAATTTACTTTCACTACAGGGGAACTTCACTGTAAGGTTTACTTATTTAAAATTACACATACATAGCAATATTGTAGCGGTATGAGTAATGAGTGAAAACTATGTGAAGAAATAGCTTGATCTTCCTTGCGATGTTGTTGCCTGAATAGCGAAGATAATTTACAGACTGCGGTTTGCGGTATATGGGTAAAACACCGAAGCTAGCTCCAAAGCTTATACAATTCCACAGGTAAGTTTGGATAAGTTTAGTAGAACTGTAAAAACCGAAGTTAAAAAACTACTTAAAAGTTAGAAAAATAGTTACGCATTTTGTGGGTTAACTTTAAGACCAATTGACCTAATAGAGGTAGAGAATATAATGCCTGGGTCTAAAAGTGGTGACAACAAATGTAAGAATAAATGATTGTTGCACAAAATTGCCACGATACTAAAACTGTCTTAGATTACAATAGTTGTCTAAAACTGAAGTTACAGGAATTACCTGATAATTATTTATGGATGGATGACGCTAAGACAGGGATGTACCCTTGAATTAGGGCGTTTAGGAGAGAAGCCGTGTGAGGTGAAAGTCTCACGCACGGTTTTGAAGACGAGTCTGGTAAGGTAACTTACTGGGCTTAGTTTAACAGTAAAGTTCAAAGAAACGATATTATTACTTCTGTTGAAGCACAGAAGTATTTAGCCTGGGAAGTTGAAGAAATTTGTAAACCTGCCTTAGAAAGAATACCTACTTGGTCTCAGATGAATCAAAATCAAAAGGGAGCACTTTATAGTTTTGCCTACAACTTGGGTGCAAATTTTTATGGTGGAGCGAATTTCCAGTCTATTACAAGGGTTTGTGATACTGTTTCTAGGTGGAAAGATCAAGGTTGGATAACAGAGCAATTTGAAAAATATCGAAACCCTGGTTCTGCTGCTGAAGAGGGTTTGCGGAGACGCAGACATGCTGAAGCTAAACTATTTTGTAAGCCTGCAGAAAATATTGAGTTTCATCAAAATAAAATGGAGGAAACAATGGAAATTACTACTGTAAGTTTTACCAATTCAACTTGGTTAAAATCCAAACCTATACAATCTTCAGAATTGTCGAACAATCAGAAGATATTTGTCAGACAGGAAGACAAAATCAAGGTAAAGGGAGTATTTCCAGATGCTAAACAACATACTTTACTTACATTAGAAAAGTCAAAATTAGCAGCTGATGGAAAGACCTCTCTTGAAAAAGTTTATGCTTATACACCTCACCTAAAATTAGAGCAACCACAAAATGAGCGGGTGAAAAAGCTAGATGTGCCTTATTTCTCTCAATTAGATAATTCAACTTTGCTTTTTGGTGCAGGAAGTCGCCAGTGTAATTTAACTTCTTGTTCTATGTTCTTAGCGGCTTTAAAGCCACAGTTAGTAAAAGAATCAAAAATTGATAATTACGAAGAATTTGAAAGTTTTTATGGGGAAAAATTAGTAAAATATGGTGATACCACTAACCATGATGCAGTGCGACTCGTTGGCCACTAAACTAGGAAACTAGGTATACATGGCCGTTCCAAGTCACCACATGAGGACAACCTCGACTTGTGAATAACTCTTATTACCTTGGTGGTGAAATTCCATCCGCCTTGTTGTTGGGTTGACAGCATAGACCACAGGGTAGCGACTGAACATCAATCCCTGAAGCTGGTCTAAAAGCGGGAAAATACCAGTTACCGAGGAACGATACCGCAAGCAAAGGCTGACAAGTGGACGAACAGGAAGGTAATAAAACTCCCGTGAGGTCGAACCATTCCAAAGGTAGCTATGGGATGTAGGACGAAAGTCAGGGGGTCAACGAACATAAGTATTGCTTTGCTTATGTTAACAATCATATAGCACCCTCCGGGGGAGTTTACCCCACTTAAGTTGGCCGTAATAAAGGAATAAGGGAACGAGGAAACCTCTTTAAGACACCTAAGTATATAGGTCGAAAACTTAGGAAGCCATTCAAGGTCAATCTGCACAAAGTTGCAGGTCTTGGGGAGAGTAGGATTGGGTAAGAAGCTCATTGAGCAGACGTACCCACTGTTAGACGTAATGTGGAGTAATAATTAGCAATGAATAAAGCTAAAACCCTAAAAAGATGTTTGGGAAACCCTAAACCATTTTTAAGCGTGGCGTGGGATACAAACGATATACCAAACCCATGTAGTGTTAATCCTAATTTCAAATGGAAAGACATCAATTGGAAGAAGGTAGAAAAGTATGTATTTAAGTTGCAAAAATTAATCTACAGAGCATCCAGCCGTGGCGAAATCCGCAAGGTGCGTAAATACCAAAAACTTCTGACCAAAAGTTATTACGCTAGGTTGCTAGCTGTTAGGCGCATAACTCAGGACAATCAGGGTAAGAAAACTGCGGGTATAGATGGTATAAAAAATTTACCCTCTATGCAGAGATTTAACCTGGTAGACTTATTAAAGAGACATCGCTTCAAAGCAAGCCCAACCCGTAGAGTCTGGATACCAAAACCAGGAAAGGATGAAAAGCGACCGCTCGGAATCTCTACAATGTACGACCGTGCATTACAAGCCCTGGTAAAGCTAGGTAGGTCACCAGAATGGGAAGCACACTTTGAACCTAACAGCTATGGCTTGAGACCAGGACGGTCAACACATGATGCTATTGCAGCAATCTATGTCAGCATCAACAAAAAACCAAAATACGTTCTAGATGCTGACATATCCAAATGTTTTGACCGAATTAACCATGATGCGTTGTTGAGAAAAATAGGACGAACACCCTACAGACGCCTAATTAAACAATGGCTCAAATCCGGGGTATTCGATAACAAACAATTCTCAGACACTCTGGAAGGTACACCACAGGGAGGGGTGATATCAACCTTACTAGTAAACATCGCCTTACACGGGATGGAAAAATGTCTAGAAAAATACGCCGAAACTCTACCGGGTAAAAAGCGTGACAATAAACAGGCATTATCCTTAATACGCTATGCTGACGACTTCGTTATCCTACACGAAGACATCAAAGTAGTAATGCAGGCAAAAACCGTAATACAGGAATGGTTAAACCAGGTAGGATTAGAGCTAAAGCCAGAAAAAACCAAGATTGCTCACACCCTGGAAGAATACGAAGGAAATAAACCCGAATTTGACTTTCTGGGGTTCAACATCAGGCAATATGAAGTTAAGTCAACCAATCAAGGATTCAAAACAATAATCAAACCATCATCCAAGAGTGTCAAAACTCATTATCGGAAACTGGCGGATAGATGTGACAAGAACAAAACCGCCCCCGCAAAAGCTTTAATAGCTAAACTCAATCCGATAATAAGGGGATGGGCCAATTACTTCTCCGCCATAGTTAGTAAGAGTACATTCAATAAGTTGGATATGCTTTTGTGGAAAAGGCTAGGTCGATGGGCAAGTAGGAGGCACTCGAACAAGTCGGCCAAGTGGGTTAAAGAAAAGTATTTCCCTCGCTACAAAGAAACCAGGAACTGGATACTTAATGATGGCGAATATATACTCAACCAACACCTTGACGTGCCTATAATAAGACACGTCAAAGTGAAAGGTAATAAATCCCCATTAGACGGTAACTGGACTTATTGGAGTAGTAGAATTGGCAAACATCCAGGCGTAAGGAAAGAAGTCACAACGCTGCTAAAACGGCAGAAAAATAAATGCGCATTTTGTGGGCTAACCTTCAGGTCAAACGACCAAATGGGAAGTAGACCATATAAAACCAAGATCTGAAGGTGGTGACAACACATATAAAAACAAACAACTGTTGCACCGACATTGTCACGACAGTAAAACTGCATCAGACAAAGAGACATATCCTGAATTCAGGCCAAGGGAAGTTCCCGAAGGATATCAATGGGTTGATGATATGTTGATTCTGAAGCAGGATGTACCTATGAAAAAGGACGTCTAAGAGAGGAGCCGTGTGAGGTGAAAGTCTCACGCACGGTTCTGAAGACGAGTCGGGTAGGGTAACTTACCTGGCTTAGTTTAACCAGACTAAAGCATTAAGAGATTTCGGAGTAGAAACTTATTTTTCTGTGCGACTCGTTGGCTAATAAACTAGGAAACTAGATATAAATGGCCATCCCTAGTCAATATATGAGGATAACCTCGACTTGTGGATAACTCTTATGTCCTTAGTGGTGAAATTCCACCGCCTTGTTGCTGGGTAGAAAGCATAGGTCACGGAGTAGAGACTGAACATCAATCTCCGAAGCTGGTCTAAATGCGGACAAAGCTCTAACTATCAAAAGAGTGAGTTTGCTAGCAGAGGCTGAAATGTGGACGAACAGGAAGGTAATGAAACTCTCGTTAAAGTTGACCATTCCGAAGATAGCTATGGAATGTAGGGCTTATAGAGTCAGGGGGTCAATGGATGACTATGTAGAAAAGTAGTCATTAGCAACCATACAGAACCCTCCGGGAGAATTTACCCCGCTAAATCAGTCGTAATAAAAGGCGTAAGGGAACGAGAAAACCTCTCTAAGACACCTAAGAATATAGGTCGAGAACTTAGGAAGCCATTCAAGGTCAATCTACGCATAGGGTTGTAGGTCTTAGGGAGAGTAGGATTGGGTAAAAAAGCATATCTATGCAGACGTACCCACTGTTAGACGTAATGTAAAGTAATTAATAGTGATGAATAAAGCTAAAACACTAAAAAGAAAGCCTTGTAATTCAAAGCCCTTTTTAAGCGTGGCATGGGATACAGATGATATAACGTCCCAAGTGAGTGTCAATCCCAATCTCAAGTGGAAAGACGTTAATTGGAAACGGGCCCTGAAGAATGTATTTAAGTTGCAAAAGTTAATTTACAGAGCATCCAGCCGTGGCAAAATCCTTAAGATGCGCAAAGACCAAAGGCTTCTGAGCAAAAGTTATTACCTAAGGTTACTAGCTGTTAGGGGTGTGACTCAGGATAATCAAGGGAAGAAAACTGCGGGTGTAGATGGGATGAAAAAACCTTTCTCCAATGCAGGCATTTAACTTGGTTGACTTATTAAACACAGGCTACCTTAAAGCAAGTCTCACCCTAGAGTCACCGATACCAAAACTAGGTAAAGATGAAAAACGATCGCTAGGCATCCCAAGGATGTATGATAGGGGGTTACAACCCTTGATTAAGTTTGGTATGGAACCTTTTGAGGGAGGCACATTTTGAACCTAATAGCAAAGTATGTTCTGGGTGCTGATATATTTAAGTGTTTTGACTGGATATACTATGATGCACTGCTAAGAAAAATTGGTAGAACATCATATAGATAATTAATCAAAAAATGGTTAATGTCTGGAGTGTTTGACAACAATTAATTTGACCTACTCCTCTTGTTACCCTCCTAATGAAGGGATGGGGTTGGTTAACCAAAGGTAGGGGTTGTCTGACCTCTAAAGTGCAAACATAGTCCTACACTTTATGGAATAAAGGCTAATGGAATTTGTCGAAAAACTCCCTCTAAAATATTCAAGTGGGAAAACAGACAAAATGAGATTAACGACACAGCCTATCCTTAATAGGCTATCCTGATGACTTTGTAATCCTACATGAGGACATCAAAGTAGTGCTACCAGCAAAAGCCTTAATACAGGAATGGTTAAACCAAGTAGGATTATATCTAAGACTAGAAAAAACTAAAATTGCCCACACTCTTGAAGAATATGAAGGGAACAAACCCGGATTTGACTTCCTGGGTTTCAATCTTAGGTAAGGTCAGGTAAAGACAGCTAAAAATGGATATAAAACTTTGATTTAACCATATGCAAAGAGTATGAAAACTTATTATCGGAAACTAGCAGATATATGTGACTCTTGTATAACTGTACCAGTTGAAGTTTTAATAGCAAAACTAAATTTGGTAATTAGAGGATGGGCTAACTACTACTCAACCATAGTCAGTAAAAAGGTATTCCATAAAATGGATATGCTTCTATGGAAACCCATAAGGCACTGGGCAAGGTCGTTGGTATCCAAATAAGAACCACACTTGGGTAAAGAAAAGGTATTTCCTAAAAATTGAGAATGATAACTAGATTCTTGATACCGGCAAATATATGTTAGATAAACACTCAGATGTACATACTTAGTTGGGCATATTAAGTTAATGGGTAATAAAGCTCCCTATGATGGTGACTGGAATTATTGGAGTACCAGAACAGGTAAATATCCAGGGGTAAGGAAAGAAGTCTCAACGCTGTTAAAACAGCAAAAGAATAAATGCGCATTTTGTGGATGACACTTTTGACCAACGGATATAATTGAGGCTGACCAAATCATTCCTAGGTCTAAAGGCGGTAACAACACCTATAAAAATCAACAGGTGTTAGACCTAAATTGCCACGACGTTAAGAGTGCCGAGGATTTAAAAGGAGTTAACCATTAGGACTCATTAGGTCTAAGGTGAAATTTTAAGGATGTACCCATGACTTTGGGGCGTTTAGGAGAGGAGCCGTGATGAGGTGAAAGTCTCACGTCCGGTTCTGAAGACAAGCAGACTCTATAAAGGGCAACCGGAAATGGGTTTACTTAGTTTAACTATACACTCTCTATTGCTGATTTAATACTTTGTCTAAAGGCTGGGTATCCAGTAGTTATAGGAGTAGCTTATAAGAGTAGCGGACATATAGTTGTAGCAACAGGATTTGATCTGGATAAAGAGCAAGTTTTTGTTCATGATCCTTATGGTATCAGGTATGGTGCTAGTAATAATTATGAAATAGGTGCTTATGCTGCGTATGATCCTTATAGTTTTACCCTTCTTGAGCAAATATGGGTTGATATGGGCTCTGAGGCAGGATGGGGAAGAGTTACTCTTGCTGTAGATAATAAAAAGACTGGTTTGCCTGATAACCTCTAAAAATAAGCTCTAAAAATAATATTTGCCTTCTAAGGTTATTGATGGTTATTGAGCTATTATACTTATCTAAAAATACCAGTTTTTAAGGGGAAATAAGGGTTTGAGAACCTTTTGAAGAAGAAGCCTATTAGGAATTTATTTTCTCTAGGCAGAACTTAGGCATAAACTGAGTTATGACGCAAGATTTCGTCATTTGAAAGCTAACTATTTGGGCAGTCAACCCTATTTATTGGTTAGTTTGCTTAAGTCCTAATCAAATTAAATTTATCTACCTGTATTTTCAGGTAGATAAATTTATTTATTTTTTGATGAAAATTAGGATGCTATTGGGCTACAGAAAAATTAAAAGTTAAAAGTAATTGCTCAATGAATTTTCAGCTTTGAAATGCTACGGGAACAGTATTTTTCAATGTGCTATACCAAGTATTCTTTCCTAATAATTCAACAAAGGGACTTGGAATATCACCAAAGATACTACAAACAGTAAAATTATACTCCAAGGAGTAAAAATAAGGCTCAAAAGTAGAGATATTAATGCTATTCCTGCTGTTACTACTTTGACAATCATATATAGTAATCCGATCATCAATCGCGCTGAATAGCTAATGATTGTAAAATCCCTTCAGTTTCTTCCAGAGGACTGAGGCCTTCTCTTAATAAATTTTCTCTCAAAGATAATTGGCAGGCATCCTCATCATTGAGAGAGCGGATAACTACAGGGACAGAAGTTAGTCCAGCTATTTTTGAAGCTCTTAAACGCCTTTCACCTGCAACCAACTCGTATAAATTGTTGTCGGTAGATCGTGCTAATAATGGTTCAAGTACGCCAAACTGAGAAATAGAAGTACTGAGTTGACACAGTGTTTCTTCGTCAAAATAAGGATGTGGTTGAGAGGAAGGTAGAACAATTTTAGCTATGGAGTCTCTTTTTGTCCTATTGAATCTTGCTTCTGGACATTATGTGATATTTCTGATGCAGAGGTGTGTTTTGTGTCAAGTATAAAGTTGTGGAGGGAATTCGTTGAGTCATTTCTATGAAGCTTTGGATTTAGAGGAGTTGGATTGAAGAAGACTTAGTTTTTTGAGTAGAGGGTTTTATTTCTATTCCCGCATTAGAAAAGACTTCTTTGAATAATGATTCAAACTCAGATGGTGAGGAAGCAGCTATAGAACTCGACGTATAAAAAGCAGTGATGTTTTGTCCAGGAGCATCAGCCAGGCATTGTCTTTGATAGATGAAAGTTGACAAAGTGGAAATGTCCAATTCTCCTAAAACCTGCTGGGATCCTCTGAGGCGAATCAAGCTATGAAGTCTAAAATTTGGCCAAACATAAAATTCTTTTCAGTTAATAGTTAGGCGATCGCTAGCCAAGAAAAAAGGTTAATCAAGGCAGGAGGAGGAATAAAAAAGTCTTTCAGCAAGACAGAAGAGATAATGTTGACCTTATATTATTTGCATCATGTACCAAAATTTCAGCGACTAGGAGCAATATTTGGAGTTAGCTCATCAACAGCAAATAATATTTTTCAGGATTTGGATAGATATTTTGAGGTAATTATTACCATCTAGTTTACTAGAGGAATTCTCGGAAAAAGAAAACGAATATTTATGGATAAAAGAGGCTTTGACAGAAATAGAATTGATAGTTGATAGTATAGAGCAGGATAGGGAAAAGCAAAAAAAAATGATGATAAACAGAAAAAGTATTATTCAGGAAAGCCAAAAATTTATAGGGTTAAAAATCAAATAGTAATCACAGAAAAGGCAGAAGAAATTATAGATGTAATAGTAGGAAAAAGAGGTCGAGAAGGTGATATAAAGTTATTCAAAAAAACACAAAAAAAAGTTTGATATAGAAGAAATACTTCAAAGAGACAAGGGGTATCAATGTGGTCAAAAAATTAACAAGCTAAACAAAAAAAATAAGCCATAAAATGCCAGAATAAGTAAAGAAATAGAATCAAAAAAAAGATAAAAAAATAATATTTGTAAGATAAAAAAAATAATATTTGTAGAAAAGATTATAAGACTGATAAAAATATTTATATTGGCACGAGAAAGATTGAGGTTGAAAGAGACTAATTATGACAAGTAATTTTAAAATATATGATTTAGTAAGATGAATAAGAGGAGAATTTATATTATTATAAATCATAAGTTTTGCTCTAAAAAAAAGAAATAAATAACCAGATAAACATGGTGAATAATTAACAGTAACTATCTGTAATACTATAAAGCCCGTAAAAAATGACTATCTGGTGGAGCTGGCGATCGCTCCCCAAAAGATATTTACAGTAAGGGAAGTGATAATTTTTGGAGATGTCTATTAATAATTTTGACATAGTAACTAAATGCAGCTTCTCTTAAACTGGAAATATAGAAACTTTCATATTTTGTATTGTTTAAACGCCAGGGTATTTGAGCAGGTTCTTTTAGGTTAATGGATTCAGGAATGACAAGTAAATATTTGATAGGATGTGTCTTTTTAGATTTAATTTATTCAGTTATAACTTTTGATAAAATCAAATAGTGGCAACCAATGAGTAAAAACAGAAGAACAAAAGCAGATTTTTTGGGTTCTTAACGTTGATTGTTTTTTGCATTCTATTATGTCGAATGCTTGCACCAGGATATAACTAACTAACTAACGATAGGAGTATAACCTTCTATTAATTTATGGTTTTAGGGTTACATAATTTATGACTAAAGTTTTGATTAATATAAGAGTTCAACTGTTTGTAATAAAGACGAGTTTTTACACCATAAACTTGAAAAAATATTGAGGTTTTGGAATTATTTACCTTTCAGTAATAGACAAAATTGCTGATAAATTACTAATTTTATTAATAAACAAAGTAATAAATGAGGGTAAGGTTTTCAGCAATTTAGTTCCTGATGCTTTGTATTTTTTCAGCAATTGTTGTAAAAATTTGTTGTGTTGTAATAATGTAGTATTTAGTGCTTTATCTACATAAATTTTATTGATTAATTGCAGAGATTAAGGATTTAATACTGTTAATTAAATCAGTTCTATTTTATCTACTTAAAATTCTTATTTAAGCAACCAATTTAATACTATTTTTCTTTTCGATTCTAGTTTACAATAACGTTATATGGAGTCAATTTTTATGATATTTTACCTACTCTTTGAGATGGCTTAGAAAATATTTTTTCGAGTTTTTTTTAGAAATATATAAATTCTTAATAGTGGTATAATTTCAATATCATAATTTTAGATAATTGTAGATAAAAATTGAGACATTTTAATAATTATTATGGAGAATCATTGTAATTATAATATATAATATAAATAAAAAAATTATTGGCAACAAATACTGTCAAAAATAAATGCTTAGAATACACAGATTAGTAGAAATATTTCCACCTATGACTCCAGAGGAATTTGAGAGTCTAAAAAAAAGTATTCATCGTAACGGTCAACAAGTACCTATTAAAGTTTTAAAGTTAACTAATGAAATTATTGATGGAAGACATCGATACCAAGCTTGTCAAGAATTAAATATTGAACCTTTAATTGAATGGATTGAAGATGATTTGAAAGAAAAAAGGTTACGCTCTCTAGTTGTTAAACTTAATCTGGATCGGAGGCATTTAACACCTTCTCAAAAAGCTTGGATTGCTGCTAGTTTTGCTGATTTAGAAAGAGGACAGTTTCATGGAAATAGATATACTGAAACCTTACATTCTAATATCGGCAATTCTGCCAATACTAAACTACCTCTAGGGCAAACTCAATCTGCAATTGCTAAATGGTTTGGTTCATCTGAAAGAGCAATTCGACAAGTAAAAAAAATCAGACGTGAAGCTCCTGAATTCAATAATTATATATATATGGGAGAGGTGAAAATTGATGATGCTTACTGCTTACTATCTGAAGTTCCAGAAGTGAGGCAGCAGGTATTAAAGAGGTTCAATGAAGACAAATCTTTGAATAAGAAACCAAAAAAGCTTTGCCAATATAAAAATGACATACTTAAAGAACAAGCTCAGTCTAATATAAAGAAGGCGATCGCTAATAACTTTTTAATAGAAATATCAGAATCATTGTTAGTACAATTAGGAGAAACTTGGCAACTTGGTAGACATCAATTAAGTTGCTGTGACTCTTCTACATGGAATCCTCCTTATGCAAAACTAGCCTTTGCCGACCCACCATATAATTGTGGAATAGCAGAATGGGATTTCCATTTTAAATGGAAGCATGACTGGTTAATCAACAAAGCTGATTTAGTGTTAGTCACACCAGGGGATGAATCTTTAGCAGGATTCCTCAAAAAAACTGAGATGCCTTATAGATGTACAATTGCTCACTGGATAAAAAATGGTATGAGCAAGGGAGCAATGGGCTATGGTAATCATATATTGGGATTAGTATTTTGTAAGGAATCTACTCCTTACAAAGTTACAGGAGTCAGAAACCAAAGTTTTTCTACTGGTGTAATTAAATTAGACGAGACTAATGAGACTAGTCATCCTGGCAGAAAACCTTTAGATTTTTTAGTAACTTGGATAGAAAAGTTAACTAAACCAGGGGATTTTATTATTGATCCGTTTTTAGGCAGTGGTACTACTTTATTTGCAGCATAAGCAACTAACAGAACTTGTTATCGAGTAAAGATGTCTCCTAAGTATTTTACAGAAATAATAGGTAGATGGTTAGTATCAAATAAAGAAAAATCTGTTAGGATTTAACAAATTAAAGTAATCATGTGCTAGTGTATTTTTACAACTAAATAAGGACTTCAATCTACTCAACAGAAGGATTTAATTAATAACTTCCATCCTAGAATGGAAGAGTTAATGAGAAAAATACAGGAAAGCAAAGATAAAGATAACATCAGAGAATGTCTCTTACAAAACAAGCATATTTACGAATATAAAGGTGAAGCTAGTGAAGAAGAAGTATTAGGAGTTGATGCAGCTACAGCTTTTTGTGACTATGGAGAAATATCAACGGCTTTAGCTACAGGAGTTGTTTCTTCTACTTCAGAAAATGTCAAACCAGTGTATAAATATAAAGCTGTTTATGGTACATCTAGTGAAACTTTTTCTAGGGCAACTAATTACTTAAGATGTTGGTCTGAATTAGCTGCATTAAAATATGCTACAGAACAAGACACTTGGGTTTTGTATGATGGGAGCTTTACAAGTATTAATTTTGAAATGGGCAAATGGGCATCTGTAATGCCAAAAGAAGGAGATATATCTCGTGATTTTGTGGAATCAGAACTACTAACTGACTTATTTGTTGAGTCTATTAAAAGTGAAGATTCGGATTGGTTTACAGTATTTGGAGATAGAAAATTAAATAAGGTAATTTCAGTTGGGAAAAGAGGGATTAGTAAATACTACTCAACGAATGTAATTAAAGATTTTGAGATAGAAGATACTGCTTTTCTCCCCTCTGATAAATTTATTTTAGGCACAGTTTTGCAAGCTAATGAGTATACAAAATCTTTGTCTTATGAGCAAGTATTTGTCAAATCACATGGCTCAGGAACGCCTGGTTATGGTCATCCAGGATTAAAGTCTGAAGACCGTTTTAATTCAATGCAAAATGACGTGGAAAGAACATATAAAAATTTACAAATTTTGCATTTTAAACCCTGGCCTTGGTCGCCTGTTTTGAAGATAGAATATAATAAGGAACGTTGCGAGTTAAATGATGTATTAGCAGTTATAAAAGGGCAAACTAAGACTCGTTCAATTCTTGAACCAATGGCTTTGTATTTAGCGGATTTATTAGCTAAACAAACTCAATCAGTAATGAATTTTTATGGTGATATAAATACTCGCCGTTATCCTAAACTATTTTCAGCATATCGAACATCAAAAAGAGGTTAAAATGACAAACATTGTTGAGATTGCTTCAATCAATAGTTATAAAGGTGGAAAATTAAATGTAACTATTCGTTCTCAGGCAACCAGAAAGAGCTTAACTGGTAAAATGTGCGAATTTAAAATCGAAACATCAGACCAAGGTACACTTAGAGTATTATGTCGAATCAACTCAGTAGATATGGCTAACCCTATCCATGAGAATCGTGGTTTTCAACAAGCGATCGCCGATCAAGGCAAACTCCAATATTATTCTGGTGATTGTGATGTAGTAACAGCAACAGTTGAAATTATTTCATGTATAACAGCAGATAAATTGATACCTACAAGTATTGCTTGTCCTCCACAGTCGGGAACGCCTTTAAGGGAAATAAAAGGAAATAGTATTATTGACTTTCAACCTGAGAAACAATATAAAGGGACAATTGGAAATTTAATTGATGCACCTGAGATGCCCATGTCAATAACAGTTCGACACTTTGGTGCTTATGACAAAGGAGGTTATGGAGAAGCAAAACATAGTGTAGTTTTTGGTCAAAATGGTTCTGGAAAAACTGTTATTGCCTTGGCTAAAATAGCCTGTGAATTGGTTCAAAATCCGCAAATGGGTTGCTTAATTCCTGATACAGCAGGGGATATTGCTAAACATGGTTCTCATGATAGAGGTGATTTTAAGTTTAGTTTTTTAGAGTTGCTGGATAAAGGAGGTAGATTAGCCGAACAAATTAATATAGAAGATATTCGTCTAGTTTCCAAAACTTTTTTCAAGCAAATGTTAACGCCTATCATCCGACAAAAACTTAATACGATGCCAGATAATGCTACGCGTTTAACAGACAAAATTACCGAAAGCTTATTTGATAAAACAGTTGATATTACTAAGGCAACACCTGATGTAATTTTAAACATGATTGTTGAGAATGTAGCGACCGTTTTTTCAACTAAAGCTAAACAAAAGGAAAAAACAGAACAAGCTCAGGAGCTTACTCAACAACCCCTTAAAAGAGAGTTTATCAAAACTTATAATGCCAACGTCGTTCATTTTTTTGAAGGAAAGTATGCTTTGCCAGAACTCGTTGATGGTTTTCTTGATAGAGGGCGGGTGATTTTACTCAATATGTCTAAACTATCGGAGCAAGCACAGCGCAGTGTAATGTATGAGATATTTGCTTATGTAAAATCAAAGTCGGAAAAGGACTATAAAGCTTTTAGTAAAACCCGAAATGGCTTAATTGTTCTTGATGAAGGACCTCGGTGGTGTCCGCAATCAGGTGGAGATGAAATAACCAGTACAATAATAGACGCTTACAATACTACCCGAAAGCTGGGTATTGGTTGGATGATTATTTCTCAAAGAATTACTGCTATTGATAAAAATATCTTAGCACAAGCTCATACAAAATTTGTCGGGCGTGGAATGGGTATAGGTGCTGATGCTGAATATATTAGTACTTTATTTGGTAAAGAAGGGTTAGTTATGTATGATTCATTAAGACTTAGGGGAGGTTATTTCTGGTTAGCAACAGGACATCAGGTTAACTATGGTCAAGGTTCTCAATATATGGCTTTTGATTCTTTTGGGGGAAATGCAACAGCTAAGATAATTAAAGCTAATCCTCATATTTGGCAAAATCAAGAAGAGATGTCTTTAGTTGTGGGAAGGGATGATAAAACTTTATCCTAACCCTGAGTTTTAAAATTCAGATAGGGGGATAATTAAGGTTACACATTTTCTAGGCATAAAAATTCTTATTTGCGTAGCATGACAAACGGCAAGGTTAGTCTAGGTATAATATATATCAGATATAGTAGCGCTACTTCCTTTTCTCTCAAGTTTATTACTTCAGAGACTTCCCTTTCAAATTTTGGTACAGACTCTCAGAAAATAAATGTTTGAATTCCAAATAATTGACTATTGACTACAGAATTTATTGATAGCAATTCTATTTTATTTATGTATAAAAAACCTTACTGTTTTTAGGAAACAAACAACAGGCAATAGGCAACAGGCATGATTTTCAAGTTTTTTATCTACTTTTTTATTTGTCACAACCTATTTAGGATTGCTATATAAAAAAAATAGATTTATTTGTTTGAATAAATAAACTAAAATCTACTGCAATCAATAGATGTGGAGGTTTTTATTTTAACTGACGTTTTTCGTATAAAATTTATTCTATTTGACTTGAAGTGATTTTGCATAAATTTAACCTCCTTAGTCTATGTAAGCAAAAAAATATAAAATATAGTATAATAAAAATACCTAGAGAAATGCTACCAACATTTTTCTAGGAAGTCAAGTAAATCCTCAGAGACTTAAAGCTGACTAGGCAATTTATCTGAGGCTCTATAATTTAAATATAGCATAAATGCTACAAAAAACAAAAAAAGCTGTAGTTACTACAGTTAAAGTTGGTCATATCGAATTTGAAGGCTTAATGCTGCCAAATGGTAGCTATGCAATAGCCATAAGTCAGTTAGACGCTCTTGGTTTGATCCGACAAAACAAAGCATCAAAAGTTCTGAAAGCTTCGCTAGGAAATAGTTTCCAATTCGACAAAACTATTTCCGAACTAAACCCTAGAGCGGTTAATATAATCTCGTTATTGGATTTTGAAAAGCTATTAATCAAGTTAGACAGAAAGGGACATAAACCTGCGCAAGATTTAAGAGATGAGTTAATTGGTTTATCTTTTAAGCAGGTGTTATCTGAGGCTTTTAGGCAAAAGTTTGAGAAAGATGAGAATCAACAATGGCTCAAAGAGCGTCAAGATGGGAAATATATGCGACGTACCTTCACTGATTCAATAAAAGACTACATTGAAAATAATCCACAACTATCAAATAACGATAAAACCTGGATATATTCAAATGCTTCGGATACTCTTAATAAGCTAATGTTTGGGCGAACTGCAAAACAGCTTTGTAAGTCTTATCAATGTAAGAAAGACCAACTTCGTGACCAGTTTGAGCGCAAAGATATAATAGGCATCCGACGGCTAGAAGAGCATGCAATGAACCTTGTAGATCGTCAAAATGTCCACCCCGTTCAGGCTGTTAAAGAAGCTTTTAGTTTCTGGGATGGTGCTAGGGTCTGATTTCTGTAATTGTTGCTTTTGCTGTGGGCATTAAATTTAATTTGATCATATCTTCATTAACAGTTCTCAACTTAAAGGAGAAAATTCTGCTCAAGAGTCAATAGCTAATATTGTAGGGGTAACTCGGAGTAGATGATATCAAATCTCACAAGCGATAACAGAAGGGGGATATAAGCAAATCAAAAAAATGTTAGTTTTGTTTGTAGAGAGTATAAACAAAACTAACATTCCCAAAAAGAGGCTTTCTCTGAGTTACCTGAGGAAGTTAAATGGTTTATTGAGGAGTAGATTCCAAACTTCCATGAATAGAGAAAGGGGAAAATATAGAGGAAATAGCCCAACAAGTAGAGGTTATGATAGCAAGTTTTGGAGAAAAGATTCTAGAGCATATCCCAATAAAGACTCTTTTACCCCTAATAAAGTTGTTTTTGGCCCCAATGCCCCCTGCTTTTTGGGAGAATTTGCGATCGCAACTAGACCCGATACCTATTTGATGTCCTAAAATATTTAAAAATCTAAGTCCTATTATTGATAGGCCTGCTTTGTTATGGCTTAATAGACTTCTAAGTTAGGCTCGCACAAGATCCCTATTATATGCGCCGAAAAATATCATATCCTCCCGTAAGGGAGCAAATCTCCTCTATTAAATAATACTAAAATATACTTGTAGTATTATTTGACTAATTAGCCATTTAAATAACTAACACTATTCTGATTCAGCTTTTTTATCCAATAAAATCTGATAACCTTTCTGAACTATTTGAGTATTAGGATGTTCATCTCCCAACAGCCTCTTAAATATTTCTAATGCTTACAAATACAAAGATTCTACTTCTTTATACCTTCCTTAATTATCATAAAGTGATGCCAAATTATTGAAGCTACTGGCAACATCAGGATGTTTATCTCCCAACAGCTTCTTATTTTATGATTTTGATACCATTTGATACCATACTATACTATTATTTTTATTATTTTAGATATGTGTAATTAATTTTGTGTACCTATCTTATAAGTATTGCTTTGGATCAAGCTCAACTACAAACAAAAAAAAGAGAGGAAATCAAAGCTTAATATTTAAAGTCTCTCTTTTTTTTTTACAAAAAAAATTACCTCTGGGTTATTTTTAATTGTTTAATTTTTACCTCTGATAACTGGTAATTATTAACTGATAAACTTCATAATAAACTATCTCCAAATTCTTCACTAAAAATATCTAACTGCTCCACAGTTATAATTTCTTCCTCTTCTTTTTTATTAATTCCTTTTCGTAAACCAATAGCTATTTTGCTATGGTTTTCAATTTGCTGCATTACCTGTCTTGCTCTTGCAATTACTGAATCTGGTAAACCAGCTAATCTTCCCGCTTCAATACCATAAGACTTATCCGCCCCACCAGGTTGTACTTGATGCAAAAATACAATTTTATCCGGCAATTCTTTCACTGTTACCTGATAGTTTGCCACATTATCCAAAATAGAAGAAAGTTCATTTAATTCGTGGTAATGAGTAGCAAAAATTGTCCGAGACAAAATTTCCGTTGCCAAATATTCTGCCACTGACCAAGCAATCGAAATTCCATCAAAAGTTGCCGTTCCCCTGCCAATTTCATCCAACAAAACCAAAGACTTTTCCGTAGCATGATTCAAAATATTTGCCGTTTCATTCATCTCCACCATAAAAGTTGATTGACCAGTAGCTAAATCATCCACAGCTCCCACACGAGTAAAGATGCGATCGCTCACCCCTAAAACAGCAGAGCTTGCCGGAACAAAACTGCCAATTTGTGCCATTAATTGAATCAATCCTACCTGCCGTAAATAACAACTTTTACCACTAGCATTAGGACCAGTTAAAATAATTAAATCCGGCGCCGAATAGGGAGTAATTCCCGAATTATTTTTCTCTAAATTTTTACTTCCCAATATAGCAGTATTTGGTACAAAAAACCCAGCAGGTAAATATTTTTCTACCACCGGATGACGACCTTCAATAATTTTCAATTCTCGGCTATCAACCATAGTAGGACGGACATAATTTTGATAAATTGCTACATCTGCCAAACCACATAAAATATCAAGAGCTGCCACAGCGCGGGAAACATTTCTAATCTCTTCTGCATATTCCCCTACTTCATTTCTTAAATCAACAAAAATATCATATTCCAGCTCATTCAAATCATCTTGTGCCGTTAAAATTCTAACTTCTCTTTCCTTTAATTCCTCAGTAATATAACGCTCCTCATTCGTCAAAGTTTGCTTCCGAGTATAATCATCCGGAGCCAAATTTGCCTTTGATTTAGAAATACTAATGTAATAACCAAAAGCCTTATTATAACCAACCTTTAAATTAGGAATTCCAGTCCTTTCTCTCTCCGTTGTCTCCAAAGAAGCAATCCATTTTTGGTCTTCTTCTGCTAACTTCCGCATCTCATCTAATCGTTCATTTATACCAGGGCGAATTAACCCTCCTTCTTTTAACTTTTGAGAAGGAGACTCAACTAAATTGGAATGAATTTTTTTTCCCAATTCTTGTAATATTGGTGGTATTTTTTGCAACACCTTTAAATAAGGAGAATTACCTTGAGAAACGAAAGTAGAAAGTTCAGGAAGTTTCGTTAAAGAGTCAGCTAAAAAAACTAAATCTCTAGCATTTGCCGTACCAGCACCAGTACGGCCAGTTAAACGCTCTAAATCGTAAATTTGACGTAATACTCTTTGAATATCTTGACGTAGATCATTATTTTGTATCAGCTCGTCAATAGTATCATGTCTAGCACGAATACCCTTCAAACTAAGAAGTGGTTGTTGCAACCAACGTCTTAAAGCACGCCCACCCATTGCAGTACTAGTCTTGTCAACTACCGACAACAACGAACCTTGATAACTACCATCCCGCACCGTTTGAGTAATTTCTAAATTCCGCCGACTCTGGTGATCGAGAATCAAAAAATCTGCCAAAGTATAGCTACGCAAACGTTGTAAAGGAACTTGATTTTCCTTTTGGGTTTCTTCAAGATATTCCAGTAAACCTCCCGCAGCACGCACCCCCAAAGGAAGACGTTCGCAACCGAGACCTTCGAGGGATGCCAGTTGAAATTTCATCAACAGTCGCTCCTTTGCCTCCCCCAAACTAAAAGGTTGTTGTGGGCGCAGAGAATAGCAAAAAGAATGAGGGAGATATTCCGGTAAATGATCCGATCTTTCTCCTGGCCGTAACATAAAACCTATATCTGGTGCTTTAGTCGGAAATAGCACCTCCGAAGGTTGCAAACGCATTAATTCTTGGGTTAGCTGGTCTAAACCTTCAGTTTGAGTCGTGAGAAACTCTCCAGTAGAAATATCCGTGTAAGCAAGTCCCCAATAATTTTTGGCAATAACGACTGCAGCTAAATAATTATTGTAGCGTGCTTTCAGCATTCCATCATCGGTAAGAGTGCCGGGAGTAAGGATGCGAGTAATTTCACGCTTGACTTGACGGTTTTCTTTTTTAGCAATAGCAGAGTCTTCTACTTGATCGCAAACGACCACCGCATAACCTTTTTCTACTAAGAAAGTAGCATATTTTTCTACCGCATGATGAGGTACACCAGTCATGGGGACTCTACCAATTTCTTTGCCAGCGTGTTTAGTGGTTTGTACTAGTTCTAATTCTTGCGCGATCGTAACAGCATCCTGAAAAAAACACTCAAAAAAGTCACCTACTCGAAATAGTAAAAGAGCATGAGAATATTGTTGTTTAACTTCCACATAACGTTGCATCATTTCTGACAGTTTGCTAACGTCAATTTTACTATAATCAGCATTAGTAGGAAGAGAATTTTCTAGTTCCTCTTCTTTGGGTTGTGCAGATTTTGGAGTAGATGTAGATGCGGAATATTTCATAGATATTAAATCGTTTATTGAATTTTATTTAGTCTAATTGTCATTAGACTGTATCAGAAAAATTGTGTGTTACTTTAGATAATAGGAAATAGGAAAGAAATTACAGAGAAATGTCCTTTAGTATAGGAATTACCCACGCCGAACAAGGAACCAGGTTTATTGCTCTGATTATTTTTTGGCACAACCAAAATTGCCCATCATAATCAGGTTTTTGTGTAAATCCTAAGAGAGTAGATGGGAGAGTAGATATTAGTATGATGGGACATCTAATACTTTAAGTGAATGGAATATACTTTTTTATGCCGATACTACCAGTACTTTGAGATTTTTGAAACTGAAAATATCTTAAAACCAACTATTACCAAGGAATACATCATTCTTGGCTAAAAATTAGATGAAATCTAGATACATCAAGAAAACAGCTAATTTAATTGAAAAACATTTCTTAATAACATTTTGACCTTATTTTTAACCTATTTTTTCCTAAAGTCCCACTACCAAATTTGATATTACCGCAAACTCCAAATTAATATAGTCCAATTTAAGGAGGTAAATATTTTTTACGTGTTGCTAAATTTAGGGATGAATATAATTAGGGCGGGCATTCTACCTGCCCAAAAATATAACGAACAACATTTGACCATGAGCATAATTTGTGTCAATGCCTTGAGAATTCATCAGCAAGCCCTAAATAGAAAAAGAGGCCATCATGGTCTCTTTTTGAAAATTCAGATTCTCTTTGTAGCTAAAGGCCTGGAGATTCTCCTCAGAATAGGATTACCCATTTGCATTCCCCAACTATAGGCGTTTTATCTTCCAGGGGCAAAATCTTGAGTCCACTTAAATTCAACACTTTGCAACGTTTAATCTAGAGGTGGTTCTGATTTATATAACTGATATAAAACAGCACTTGTTTATGATATTTCAATATTTACAAACTACTTTTGTTCTAGGTAAAGCATTTACTGGTCTGAGCGATCATCTTGATTCCATCTTTGTACTCTTGTACTGGTCATTTATGAAATAATTACCAGTTTTTTTTAATAGCCCCAACCACTATTCCTATAGTTAAATAATCGTAAATATATGCCTTAATACCATTTATGATGTGACTACTTTATTCCTACTTGAGGGAAAGCGCATATATTAACTCCTAATATTTCAATAGCTTCTCTTGAGTTGACAAATTTTACCACAATTATGACGAATGAATTACTAGCACACTCGAGACTCTTAGATTAGTAAATTGTCAACTAAGTTATAGCTATCTTCAAAGATTTGTTTTATTGGAAAAACTGGTTGACCTATAAAATTTTACTATAAAATTTTAGGGGGAAGCTTTGAACCCAATTATTGGTAATTTAAAGTAACCCAGTATTTGCCCCTTGTTTACCAGTAGCCAACTCTACCTTGACAATTTTTCCACCCATTTTCATAATTCTTTGCTGTTCTTTGAACCAGTTATCATAAGGAACAAGCTTGGTAAAGTAGGTATTTTGTAGTTCTCGTTGGGTACGGATCCGAGTTTGACTAGGAACGCAAGCTGTGATCTTAAACATTCTCATGGTAAAAATTTCTCCTAATATTTGGTCAAGGTTTTCTTATTTCCTTACACTGATTTCTTTGTTACAAATGCGCTTAGAAGCTCTTAAATATATAGTTTATAAAAATATAGTTACACAAGACAGAATATCCTGCATGACAGGTATTTTCTTGACTGTGTGAACTACAACAACTATTATCCCATGCTCAGAGACATCAGGAAGCTGCTTTTCTCATAATGTTCAATAATTTTTCACATTACTATTTGATTAATCCTTTACTGTCGATACTTTATGCATTCCTCTTTTTACAATTTTTCCCTAAAAAAAAAGTGCCTTGATTTTTTGTGCTTTTCAAATGAAAACCGAAGAAAATCGTTATCTATAAAACTTGCTTTTGAGGTATGAGGTATAGGCATAATATTCTACAATAACTATTACATTTATCTCTACCCAATACGGCTTTATAAGATTAAATTTAATTAACTTAATTATAAGGGATACAGACAAAATATGAAATATTTCTTTTCCCTAAGTTTACCTTTTGCTTCTCGTCTTCATCTTGGCCTCTTATCAAAGTTACTCTATATCTGATTAATCAGGATATCAATAATCATTCATATATGCTTTACTGAAATAATCATATATGAATGAATTCTTTTTTTAATATCAGCCTTTTCAGTCCTAAGCTTAATTAATGTTTCTAGAGTTAAGATTTTAGGAAGCTTTTAAATTTATTATAGTATTGATTGATAAATTTTAATAGTCTACCATTTATCAAGAGCGGTTTAATTCCGGCTTGATTAAAAATTTCAGCTCTAGAGCCCATAAAAATATAGCTAAATTGTTTAATCCGAAACCAATACTGTGGCAACGATTTTTCTTTAGCTCCTATTGTTTTTAAGTAGCTTCATAAATAACTTTAATTGACTTTATAGTTAAGTCTAGGAACGAGAGGAACTTGTTAGGAATATGAAGTGGGTACTAAGATTTTTAAATAAATCCCAGTTTGGATCATATGAATTATTCCTTGCTTAAATTGCCTCTAGCTGGTGGCTTGTATCGTCAAATATCGAACATTGCTTCTAGTTTTTTTATTTTAATATCTAAAAACCTTGACTGTTTCTCTTTAAAAAATTCATTCGTTGCTAAAAAACTCTTCGGAGTTTCTCTCTAAAATCATCAATAAAAGTTGAGATACTTTAACTAGCATTGCTTAATTGCTTGATAGTCTCCTTGAGATTGCAGTGTTTTTTGTAGATCATAATAGTGACTATAAGTATTTTCAAATATCTATGACTGACGAACTAAATAATTAGTCTAGCCACATAGAGATTTATATATCAAGAAACTAAGTCAATCAATTTAAGCCAAAAACAGATGATTTTTATGAATCATAAGTCTTTCAACTAATCTGATAAATCAAGATGTTAAAATTACTAAAGGAGCCAAGCACTTAAAAATTTTTATAATTATTTATTATTTAAGTATCAGCCAATTTAACTATACTATTAAACATAAATTCTAGAGATATTAAATCTTGTAGAATATTGAGTATATCCTTTGTACAAATAAACGAAGATATTTAACATTATTTGACTATATTTGACTATATTTATGTAAACTTTTAATCTACCAGATTACTAGCACCAAACACCATAACTCTAGTAAAAAATCCACTAACGTTACTAAATAACCTCAAACTCAAGTCTAACAATATCCAAGGCAGGGAGCCATAGAATAAATGCTAGTGTACTAAAACTTATATGTTCATTCAATAAGCCTTTGGTAATCTAACACTCAATCTAGGTTTCCCTAGCCTAGAAATAAAAAATCAATTAGAACAAAAAAGAAAATCAACTCTTTTTTCTATTTTCTATTTTGATGACTGGTTGCTAAATTAGCTTAAACCTGAGCATATATAGTCAAAGTAAACACCCATTTCCCTGCCAGCATCAGGACCAACTAAACTAGCAGTAACTTCCTTCATAGCTTGAATAGCCTGCACTGTAGCACCAATGGGTACACCCAGAGAATTATAAGTTTCTTTTAGACCATTTAATACGCGCTCGTCTAAAATAGAGGGGTCTCCTGCCAGCATAGCATAAGTAGCATAACGTAGATAATAATCCAAGTCACGAATGCAAGCAGCATAACGACGGGTAGTATACATATTACCACCAGGACGAGTAATATCAGAGTAAAGTAGAGCTTTGGCTACAGCGTCCTTAACTATACCTGCAGCATTAGCGCTAATAGTAGTTGCAGCTCGAACCCTTAATTGGCCTGTTTGAAAGTAGCTAGAAAGTCTACCTAGAGCATCATTATCAAGGTATTTACCTTGAACGTCAGAAGAATTGATAACCGCGGTAATTGCGTCTTGCATTGTTGATTGATTTCCTTAAAATTACTGAATCTGGAAAATTATTAAATAATTAAAGGCCATGAATTTAGATGTTTAATCATAGACTTAAACTTGATATTTCAGGAAGTTTTAAATTGTTCAAATATTCCTTGATCATCAAATTTTATCTAACATCTATTTTTATCTAACATCTATAAAGATATTTAGCCTTAACTCATAGCACCGATAACATAGTCAAAGTAAGTAGCAGCTTCGCTACCTGCTTCATAATCTAAAAGTGAACAAGTGACAGTTTTCATGCAACGAACACCTTCAGCAACAGCTTCAATAGGAGTTCCTAAAGACTTATACATTTCACGAACGCCTACAAGTCCGATCTCTTCAATAGGAGTAACATCACCAGAGACAATACCGTAAGAAATTAAACGCAAATAATAATCAAGATCCCGTAAACAAGTAGCAGTCATCTCTTCACCGTAGGCATTACCACCAGGAGAGACAACATCCGGACGCTTTTGGAATAGTTGTTGACCAGCTTCCTTAATAATTTTCTCACGAGATTCAGTCATAACTTGAGCAATCCTAACACGGGTTTCTCCAGCCTTGACAAAGTCTTTGATTCTCTCTAATTCACCGGGACTCAAATAACGAGCCTCGGCATCTGCATTAACAATTGATTTAGTAACAATACTCATGCTCTCTTCCTATAAAGTTAAGGTAAAAGGTTGCTTGACATACTCCTAACGTTGTCCATAGTCAGGCAACATGGAGTTCTTCGACTCAATGTATTTGAATCATTGTTTATACAGAGGTAATGCCGTCCCTCTGTGTTTTTCTAAAACATTATAGCTTTTATTCCTCGGTTCCTTTACAGGAAAACATGGAATTTATGGCCTAGATCTTAAAAATGAGTTAGCTAGTAAGAAGGAAAAATACTTTCTTACATAACTACCTTCAGCAAGTATTTTGAGGCATTTTGTTCACTTTCTCATTATTTCCTTAATAGTTTGTAATATTTCCACAGAAATTTCTAGTTTTTCGGGCCAAAAATCTCATAATAACTTGACATATGACAAATATTCAAAAACTATTGGTAATATATGCCCTTTTTATTTCATTGGAGGGGGCAGACAAAAGGTCATAGGCCTACTGGTAAGTCAAAACTTATAGTTGTTTGAATTAAGATTGAGACAAAAATTGAGTAGAATAATTTTAAGTCAACTAGAAACTATTTTTCATCATACCTTACAGTTTAGACTTCAGACAAAAAGTCATAAATTTTGTATAAAATGGTGGTAAGATTACTGTAGTAGCTCATTTATTTGGAATAGGAGGAGCTTCGATATATAGATGGTTATCTCGCCCAAAATTGTCAGCAACTAAGGTAAAATGTTGTCGAAGAAAATTAGATTGGAAAGAATTAGAAAAAGATGTTAAACCAAATCCAGAGTTTAAATTGGCAGACAGAGCTAAAAAAATTGGAGTTAATCAACCAGCTATATTTTATGCTTTGAAAAGAATTAAATTTCCTTGAAAAAAACAACTTCGTTATCGGGAAATAAATAGATGAGAAAGGATAAAATATTATCAGCTTTCCCTCTAAATTTTATCAAAAAATCTAGAAGTAAAAGCTTTGTATTTATAAATAAATCAGGATTTGAAGATAATCAAGACTGTATTTATACCTGGTCAAAAAAAGGGAAAAAAGTTTATGGCGAGCAAGAGGAAAAACGAGGTAAGAGAGAAAATTTAGTAGCCGGGAGAAGAAAAAAGGAAAAAGATTTAATAGCACTAATTAGATTTAAATGA

Protein sequences of DBSCAN-SWA_8

>NC_008312|5515787:5611019|5593510_5593726_-|WP_155994476.1|DBSCAN-SWA
MDISTLSTFIYQRQCLADAPGQNITAFYTSSSIAASSPSEFESLFKEVFSNAGIEIKPSTQKTKSSSIQLL
>NC_008312|5515787:5611019|5569826_5570786_-|WP_011613026.1|DBSCAN-SWA
MSSTSKKLSTLTKSLFSAQIIVMTGLIWGVLALLFFLLFSVPLPGEELPSWYSVGTYIFELGAYLIATIISFRNWQSPQMVSGRNVWIGISLGLLFYFIGGLVFGCWELIWELDPDVSLADIFYVFSYIFLAWGMTLAITAKKLNLEFWQWVVLALVAAGGVLLAIFVADPSFFGLLSTPDTTVLEELDTIKIESAQLAPSWVLALDNKLEPFSFWLNLFYIIADVFLLIIATALLLAFWGGRFSQSWRMIAGATFSLYIADMYFKWADSQTTGEYESGGLLEVFFVFTAILFAIGAVLEYDISTRSRQSRRSRRSSSS
>NC_008312|5515787:5611019|5559754_5560492_-|WP_044137740.1|DBSCAN-SWA
MSLNVQNTNTSALNNRPFLTWQLIIDWAEEHYRSRAFSKDERIPARPGLLYLIQKGAIRLVGNANISANRNVSNNNLSKSKTSPNSDEPFLGLVGAGQPFELIAQSPFTLQAYAHIDKTTVLWMYWHELDNWPHFRREVLDAFRYQHQRKLLWLSTLGQRRTIDRLFGFLTLLIEEYGQPWTSQDNLEVTSGYYLPWPLTHTQIGSAIGSTRVTVTRLIGKLRQQGLVYIQNDNLICLPMESQNQ
>NC_008312|5515787:5611019|5525967_5526198_+|WP_155994711.1|DBSCAN-SWA
MYKFITFGGGVHPCLGAQMAMVISKVFASHLLRIFKWKITLSIQSLFVVPLRKLEMIIKFKFKLKLRIKYAILVLP
>NC_008312|5515787:5611019|5519763_5520264_+|WP_011613005.1|transposase|DBSCAN-SWA
MELELIVDSSEQSRERPKESEKPEKYYSGKKKNNTFKNQIITTPKGTEIVDVIIGERGPLSDINLLNKQRENFKDNQYFQGDKADQGAERTSTPKKKPRKKEMPEEIKEKNQQKAQKRIFVEHVIRLLKIFGIARERFRLKEKSYEKVIMVVCGLVKLRIGALILV
>NC_008312|5515787:5611019|5606665_5606869_-|WP_011613044.1|DBSCAN-SWA
MRMFKITACVPSQTRIRTQRELQNTYFTKLVPYDNWFKEQQRIMKMGGKIVKVELATGKQGANTGLL
>NC_008312|5515787:5611019|5526553_5526757_-|WP_044136890.1|DBSCAN-SWA
MILVSKRGTNLTLISTIFLSGFAGIMTINGGRSKNVFQVFIEQVLLPSLWLGAYSVMENLPDYQVPV
>NC_008312|5515787:5611019|5583928_5584057_-|WP_081432478.1|DBSCAN-SWA
MAIKYLYEGKNRAEVSDLLDCHYQTLSTWIDKFLEGGLKNLI
>NC_008312|5515787:5611019|5600691_5601420_+|WP_011613040.1|DBSCAN-SWA
MLQKTKKAVVTTVKVGHIEFEGLMLPNGSYAIAISQLDALGLIRQNKASKVLKASLGNSFQFDKTISELNPRAVNIISLLDFEKLLIKLDRKGHKPAQDLRDELIGLSFKQVLSEAFRQKFEKDENQQWLKERQDGKYMRRTFTDSIKDYIENNPQLSNNDKTWIYSNASDTLNKLMFGRTAKQLCKSYQCKKDQLRDQFERKDIIGIRRLEEHAMNLVDRQNVHPVQAVKEAFSFWDGARV
>NC_008312|5515787:5611019|5540613_5540817_+|WP_155994472.1|transposase|DBSCAN-SWA
MKEKRLIKAGGGIKKSFSKTEEIMLTLYYLHHVPKFQRLGAIFGVSSSTANNIFQALDRYFEVIITI
>NC_008312|5515787:5611019|5595811_5597071_+|WP_011613037.1|DBSCAN-SWA
MLRIHRLVEIFPPMTPEEFESLKKSIHRNGQQVPIKVLKLTNEIIDGRHRYQACQELNIEPLIEWIEDDLKEKRLRSLVVKLNLDRRHLTPSQKAWIAASFADLERGQFHGNRYTETLHSNIGNSANTKLPLGQTQSAIAKWFGSSERAIRQVKKIRREAPEFNNYIYMGEVKIDDAYCLLSEVPEVRQQVLKRFNEDKSLNKKPKKLCQYKNDILKEQAQSNIKKAIANNFLIEISESLLVQLGETWQLGRHQLSCCDSSTWNPPYAKLAFADPPYNCGIAEWDFHFKWKHDWLINKADLVLVTPGDESLAGFLKKTEMPYRCTIAHWIKNGMSKGAMGYGNHILGLVFCKESTPYKVTGVRNQSFSTGVIKLDETNETSHPGRKPLDFLVTWIEKLTKPGDFIIDPFLGSGTTLFAA
>NC_008312|5515787:5611019|5560799_5561702_+|WP_011613020.1|DBSCAN-SWA
MTILSFQCNAIHFLQKAVSLYREKLEWSYSCEKKLEVLARIEIISMKQVKNCGGIIYKSAIALKLAPVLQQPAIYIATELAKYCQEIVSLEGKKDALNFEVEVISSGMIFFKFTGLSIANWLSFLTSVPLKGERKKLQVSVEYKSDETTNLFLIQYSHARCCSLLLMGERDNLITLAPTTLESYGQFWFMTTADPIPWQKSHGQLQFLDYAEYELMAEIASSLDYIYCISSFKKTINWEKVANSLSNRFQAFYRQCRIWGKVRVENPKLAQARLGLVLATQSLLKFLLEEKLGAPAPLEF
>NC_008312|5515787:5611019|5524735_5525014_+|WP_155994471.1|DBSCAN-SWA
MSNTFVSTVIPISPSTSRRLTKSIVVDNILYKKAWTLITEPKITYTMPEHFERPETFELERFFPEHIVILNKNETLSGTIITNNFIKRCIDR
>NC_008312|5515787:5611019|5598329_5600006_+|WP_011613039.1|DBSCAN-SWA
MTNIVEIASINSYKGGKLNVTIRSQATRKSLTGKMCEFKIETSDQGTLRVLCRINSVDMANPIHENRGFQQAIADQGKLQYYSGDCDVVTATVEIISCITADKLIPTSIACPPQSGTPLREIKGNSIIDFQPEKQYKGTIGNLIDAPEMPMSITVRHFGAYDKGGYGEAKHSVVFGQNGSGKTVIALAKIACELVQNPQMGCLIPDTAGDIAKHGSHDRGDFKFSFLELLDKGGRLAEQINIEDIRLVSKTFFKQMLTPIIRQKLNTMPDNATRLTDKITESLFDKTVDITKATPDVILNMIVENVATVFSTKAKQKEKTEQAQELTQQPLKREFIKTYNANVVHFFEGKYALPELVDGFLDRGRVILLNMSKLSEQAQRSVMYEIFAYVKSKSEKDYKAFSKTRNGLIVLDEGPRWCPQSGGDEITSTIIDAYNTTRKLGIGWMIISQRITAIDKNILAQAHTKFVGRGMGIGADAEYISTLFGKEGLVMYDSLRLRGGYFWLATGHQVNYGQGSQYMAFDSFGGNATAKIIKANPHIWQNQEEMSLVVGRDDKTLS
>NC_008312|5515787:5611019|5593822_5594032_+|WP_081432482.1|transposase|DBSCAN-SWA
MASQEKRLIKAGGGIKKSFSKTEEIMLTLYYLHHVPKFQRLGAIFGVSSSTANNIFQDLDRYFEVIITI
>NC_008312|5515787:5611019|5592153_5592462_+|WP_081432560.1|DBSCAN-SWA
MADLILCLKAGYPVVIGVAYKSSGHIVVATGFDLDKEQVFVHDPYGIRYGASNNYEIGAYAAYDPYSFTLLEQIWVDMGSEAGWGRVTLAVDNKKTGLPDNL
>NC_008312|5515787:5611019|5567155_5568295_-|WP_044137744.1|DBSCAN-SWA
MKISNYNLEYTVSSTVKANKNVNTSVKSAVPRSRAVFPFTAIVGQEEMKLALLLNVIDPKIGGVMIMGDRGTGKSTTIRALADLLPEIKIVVDDPFNSDPYDPDLMSDSVRDRLVKQEEIPIFTRKVQMVDLPLGATEDRVCGTIDIEKALSEGVKAFEPGLLAKANRGILYVDEVNLLDDHLVDVLLDSAASGWNTVEREGISIRHPARFVLVGSGNPEEGELRPQLLDRFGMHAEIRTVKDPILRVEIVEQRSAFDQNPQGFLGKYTSQQEELQNKLVDAQQKLTFVEVDHDLRVKISQVCSELDVDGLRGDIVTNRAAKALAAFEGNTEVSLEDVGRVITMCLRHRLRKDPLESIDSGDKVKKVFNRVFGLAEVEQ
>NC_008312|5515787:5611019|5537641_5537902_+|WP_011613010.1|DBSCAN-SWA
MALVRSLTFSLWTLLSNTFVKNIQLILSNHLTTTQKKKSRKKEIPPEIKEENQEKAKKRIFLEHVIRLIKIFILPRERFRLKDNNY
>NC_008312|5515787:5611019|5609419_5609905_-|WP_011613046.1|DBSCAN-SWA
MSIVTKSIVNADAEARYLSPGELERIKDFVKAGETRVRIAQVMTESREKIIKEAGQQLFQKRPDVVSPGGNAYGEEMTATCLRDLDYYLRLISYGIVSGDVTPIEEIGLVGVREMYKSLGTPIEAVAEGVRCMKTVTCSLLDYEAGSEAATYFDYVIGAMS
>NC_008312|5515787:5611019|5547339_5548521_-|WP_011613015.1|DBSCAN-SWA
MHQPQISSYIGLVQSLLVSPSGNENKILQANQDLLDLGLVQVMKKIAKFNRKIDGLHAQWLENLAAILEINLKNISLSVDEKKYIIFLMQVLQIISDNDVKLENIYSLLEYNQDLLNKNFLKVIQTWAGENLPKMEQKLAQNIALDIISFSNLILQFPLGNQSNNVEIAIAGYEVALKVLSCQEFPEIWGTIHNNLGSSYQKRTIGNLEENIEVAIACYDKALEVRTNSALPETWATTQNNLGNAYQQRIAGRRKENLENAISCYQKALTVRRLEKLPQEWATTQNNLGSAYHERIAGEKKENIEVAIACYIFALKVRTKEQFPLDWATTQNNLGNVYLDRMMGDKQNNLKQAIACFVRAQEVYTQESYPVYWEIISHNLSMVYDERRLRQVS
>NC_008312|5515787:5611019|5574670_5575789_-|WP_011613028.1|DBSCAN-SWA
MLNAQTIISILLVFVPISIAANAMELGSSVIFITSAIAIIPLAGWMGTATEEIAVVLGPNLGGLLNATFGNATELIIGIIALNAGLVRVVKASITGSIIGNLLLVMGLSMFLGGLRFKEQKFQSVVARLNASAMNLAVIAILVPTAVNATSNGISSNTMQNLSVAVGIVLITVYILTLLFSMKTHSYLYEVGIVGSESQDLDSDSESEENAEHKPNLLLWILVLLIATLTVAFESELLVDSLEEATSALGLTALFTGVIVVPIIGNAAEHATAVTVAMKNKMDLSVSVAVGSSLQIALFVAPVLILTGSLLGQPMDLNFNPFELVAVVVAVLIANSVSSDGRSDWLEGVLLLAAYTILGLAFYFHPVIKGLS
>NC_008312|5515787:5611019|5591121_5591316_+|WP_155994474.1|DBSCAN-SWA
MGYPDDFVILHEDIKVVLPAKALIQEWLNQVGLYLRLEKTKIAHTLEEYEGNKPGFDFLGFNLR
>NC_008312|5515787:5611019|5543779_5544061_-|WP_011613014.1|DBSCAN-SWA
MCIEAMLSDCKKGGYNLEGSQANIQRLTNLILLVAIAYTASFYHGNYIKKLECQRYICRLNEPGRRDRRHSNFWVGIYSELWVLAGNYLVDIV
>NC_008312|5515787:5611019|5538682_5539066_-|WP_011613011.1|DBSCAN-SWA
MIVLTNGKDIVDIEAGKIGQISDINFFREIQEKFHQEQKFTRDKAYVGEPAIKTPKKKPHIQELTSKEKSQNKELASERIFVEHIIRLLKIFRVAQERFRLNSDKYTQIIMTICGLVRLGIETVILS
>NC_008312|5515787:5611019|5564311_5564803_-|WP_011613023.1|DBSCAN-SWA
MEKLILGLDPGLAVLGFGLIKCIYNSKTEKIDSTSLVDFGVIKTTKKQEMGQRLVTIYEDLHTILNNFKPDLAATEKLFFYRMGNTILVAQARGILILALAQNEIPLIEFTPAQIKQAVTGYGNADKYDVQQAVARELNLEEIPKPDDAADALAVALTASWLN
>NC_008312|5515787:5611019|5563175_5563982_-|WP_011613022.1|DBSCAN-SWA
MIKFFSKSFFVSIASIFLALSTLALTPTVAQAYNNPDLLPKEQTPIIDLARSLTEIQENLLAKDLEKFETETGWKLRVLTQFDRTPGRAVKDFWELDSKSVLLVADPRGGNILNFNVGRGLYQFLPRTFWVELQTRYGNQFFVRDQGEDQSIIQSLESIKTCLRQGGCNVVPGLPQEQWILTLITSVIGGVICGFAAQPRKPNQAFSWQWALIFSPLWGILFIAFGIGPVVSRTSDWLPLTRNVVGFLIGALVAYLTPFLNQSSPSET
>NC_008312|5515787:5611019|5610510_5610744_+|WP_081432483.1|DBSCAN-SWA
MTVVAHLFGIGGASIYRWLSRPKLSATKVKCCRRKLDWKELEKDVKPNPEFKLADRAKKIGVNQPAIFYALKRIKFP
>NC_008312|5515787:5611019|5546016_5547054_+|WP_011610772.1|transposase|DBSCAN-SWA
MNIIDKLNDFINQTKESKEIKRALAVKMTLSGKSYHEVKELLNVSHSFISEWKNQALFHGVESLRLQYQGRQGYLKTVEKEKTIEWLRAQDYLRLSDLKNYLQEQYDVVFESNQSYYNLFKEAGISWKKTQKKNPAKNDELVEVKRKEIQEFLAKWQPEIETGKLTVFMIDECHLLWGDILGYAWGKTDERIEIAIKNEKERQTYYGALDYKTKEFLVQEYESGNTKNTIEFIKYLQKQRPGNKLAIFWDGATYHNSQEFREYLMTINQYLSEEELLINCTRFAPNAPEQNPVEDIWLQTKNFSITFYHLCSSFKVVKWLFKFFADGQIFNFPKLFQYEILPQPT
>NC_008312|5515787:5611019|5565325_5565544_-|WP_155994473.1|DBSCAN-SWA
MSQLYRIILTQITTLHIRGVRRISQHYGKNYYTREANELLIGTGIFIFVIVTCIFSPNLNFSMTSRHNSIDK
>NC_008312|5515787:5611019|5591376_5591583_+|WP_155994475.1|DBSCAN-SWA
MKTYYRKLADICDSCITVPVEVLIAKLNLVIRGWANYYSTIVSKKVFHKMDMLLWKPIRHWARSLVSK
>NC_008312|5515787:5611019|5584505_5584691_+|WP_044136897.1|DBSCAN-SWA
MDEKNLIPQSGLDLIKEFEGYGKELPDGRAQAYADPIYGWEVATIGYGTTKYPNGVRLVGH
>NC_008312|5515787:5611019|5550522_5551482_+|WP_011613016.1|DBSCAN-SWA
MTKLIIQIPCYNEEECLGVTLTALPREIPGIDIIEWLIINDGSQDRTVEIAKEYKVDHIISFPRNQGLAKAFMAGLEASLKAGADIIINTDADNQYCADDIPYLIQPIILRQAEIVVGQRPIWETKHFSYTKKLLQQLGSWVVRIASNTNIPDAPSGFRAFSREAAMQLNVFNSYTYTLETIIQAGQKGITITSIPIRTNSVLRPSRLVRSTPSYVLRSLFTILRIFLLYKPLRFFLMLGSLPLSLGVISGIRWLFFFFSGYEKTRVPTLILATILVLVGFQLWILGLIADLMAANRIIMEEIQVRMRRQDCNNNNYKK
>NC_008312|5515787:5611019|5515787_5519246_+|WP_011613004.1|tRNA|DBSCAN-SWA
MVEAKSYKETVNLPQTNFNMRANSVTREPELQKFWAQEQIYERLSQTNPGEIFTLHDGPPYANGNLHIGHALNKILKDIINRYQILQGRKVRYVPGWDCHGLPIELKVIQNIKSAERAKLTPIELRRKARDFALETIDKQRESFKRYGVWGDWEHPYMTLSPEYEAAQIGVFGKMVLKGYIYRGLKPVHWSPSSKTALAEAELEYPEGHKSRSIYAAFKITNLAKAVEKSLESYLEKLWVAIWTTTPWTIPGNLAVSVNPDLNYAVVKPDADYAMGKDKLFIVAAEAVERLSATLGTTLTPVATVKGEDLENCTYQHPLFDRESKIVIGGDYVTTESGTGLVHTAPGHGQEDYIVGQRYSLSILSPVDGNGKFTAEAGEFTGLSVLAEGNIAVIEALQNVNSLLKEEPYEHKYPYDWRTKKPTIFRATEQWFASVEGFRSEALKAIAEVNWIPAQGENRITPMVNDRSDWCISRQRSWGVPIPVFYDEKTGEPLLTEETVAHVQKIIAEKGSDAWWEMSVEELLPETYRQDAEKYRKGTDTMDVWFDSGSSWAAVAQQREGLRYPVDIYLEGSDQHRGWFQSSLLTSIATNGVAPYQTVLTHGFVLDENGRKMSKSLGNVVDPVIVIEGGKNQKQEPAYGADILRLWVSSVDYSSDVPLGKNILKQIADIYRKIRNTARFLLGNIHDFDPAKDAVAYEEMPELDRYMLHRITEVFAEVKDGFDKFQYFRFFQTIQNFCVVDLSNFYLDIAKDRLYISATDAFRRRSCQTVLVVAVENLAKAIAPVLPHMAEDIWQNLPYPTPCKSVFESGWVKLEEKWHNPELVKLWEELRKTRTEVNKVLEKARAEKAIGSPLEAKVLLYVKDTKFREQIQDFNPIAQGEKSKSEFWEAKIEIEPEKTEDKTTNNQQKFPDIFYTYKNFLSDFSNTVSKLLSGYKKALGGVFLMIILLLSIQLTVTVVKTIEKLPLVNYIMILVGIIYTIRFVTHNLLFAKSRQSWLDKIKLTAEDILGKEALSTQKKNLADNTVKQSATLVYPEGVFVPPQKVEFTPEPQVVETETLPQQPNNVKAIIPSGNGVDELRYLFITSQVELLESPECLSNLEYKSILDSLGIGVVKADGEKCERCWNYSTHVGDFSEDPTICERCVVALAGEF
>NC_008312|5515787:5611019|5571977_5572649_-|WP_011613027.1|DBSCAN-SWA
MFILKRQDVEITSITHPKRDQKIPILSYQGQTFRLINVFKGEQAEEARAFWRDLTDNHGKACVLLEEPERYSVWVKIRLDQLASEDSKENKTVASACIQGCLLLVQAVYFDVEDLLGNRQAKSFQKDFSKVLQGKNFPDADSANAIKALLIDDPLTKLRLPSWQEGHLYTLLQEVYRLGEEYFGNSNFAEGIDEILEPMDTPERTQFMNWLNQFPEGKQWAIK
>NC_008312|5515787:5611019|5601721_5601922_+|WP_047165189.1|DBSCAN-SWA
MNRERGKYRGNSPTSRGYDSKFWRKDSRAYPNKDSFTPNKVVFGPNAPCFLGEFAIATRPDTYLMS
>NC_008312|5515787:5611019|5568996_5569824_+|WP_011613025.1|DBSCAN-SWA
MISQTSTPVIVCGAAGKMGREVIKTVANASDMTLLGAIECQPEYIGQDIGELIGSGPLEVPILNDLQGILVMAAQEKQPAVMVDFTHPDSVYENVRSAIAYGVRPVVGTTGLSQEQIQDLAEFAEKASIGTLIIPNFSIGMVLLQQAAIAASKHFDHVEIIELHHNQKADAPSGTAIKTAQMLSELGKTYNVPNVEETEKIEGARGCLAEEGIRIHSVRLPGLIAHQEVIFGGPGQIYTLRHDTTDRSCYMPGVLLAIRKVQSLTKLIYGLEKIL
>NC_008312|5515787:5611019|5562092_5562518_+|WP_011613021.1|DBSCAN-SWA
MSYVVVYDGNCNLCVTLVQVLEGIDKGQLFKYIPMQNDQVLNQFSITAKDCEMGMILIDTNEPKYRWQGSDAAEKIGQLLPGGDIFVAAYQSLPGAKWIGDRFYEQIRDNRYTIFGKRSNTYNSVYPVGCKTYLFQEQDSI
>NC_008312|5515787:5611019|5555123_5556713_+|WP_044137735.1|DBSCAN-SWA
MRDLFAQEALAQIPKILTLLDRNLHSPTYGCFDRNFWHYKIIDFPSGMAQEFVLPLALAYSLKIPNNPYYHQEMIHKWVEAGILYTSHAAHPDGSCDDYFPFERASGATAFSLLASIESYQTLGLNNYKILSFFEKQADWLVHHYENGKLANHEALIVLCLESLSILLETSKWDTAKANRLSRLLSWQSQEGWFTEYSGFDPGYHTLTISCLARVYELNPSEKLKSIIIKAVELATQFIHPDGSFGGEYASRNTYNFFPHGFELVGKWLPAALWINDQFLIGLKNGLAPCYADDHIIGHHTWNYLLAWRDFITERPVNINRDVASLLLEEAKILIKRRPGIELYVSLNKGGVFKLFRNQKLVASDTHLSLQVRKGRKILNAVSHLSGNYDVDISQDEIVISANMGWAKQTQMSSLKLIILRLVMLTFGRFFPNLIRKILQKILITGKQDAPFSFKRHFKYKDGSWHITDELFAKSWLDVISAGIGCDQTSIYVVMSRTFQISQLQSWHDLTTEIKKLSPGQPLKIERKF
>NC_008312|5515787:5611019|5528883_5529381_+|WP_044136891.1|DBSCAN-SWA
MTYIGTREAAFLLGICCQRVRALLSQGRIKDAYKDNGLWQIPLYGKMPIVIPGKRGPKGVWCHHKRKHPTKIHVNQHFIKVNAKRINEDPLMTPDQLIPVITLKQTNRNDMGYQMVLDGQCRIVYKPYEPLPCGAHLWIETYKPVQFVDTRFKPRSARRPYKDIC
>NC_008312|5515787:5611019|5566114_5566417_-|WP_044136896.1|DBSCAN-SWA
MADTRLYSEFADKKNYEQLSTGIIKILWYSLKDFILAMQRTECLYFIQKWNIKKPPFINHQLISTNKFFQMQTRISNNLFMVIFLFITAIIVWVIIFYFR
>NC_008312|5515787:5611019|5593047_5593380_-|WP_081432481.1|DBSCAN-SWA
MAKIVLPSSQPHPYFDEETLCQLSTSISQFGVLEPLLARSTDNNLYELVAGERRLRASKIAGLTSVPVVIRSLNDEDACQLSLRENLLREGLSPLEETEGILQSLAIQRD
>NC_008312|5515787:5611019|5541894_5542107_-|WP_044136893.1|DBSCAN-SWA
MDGSFYPGQGRGEDVAYGHKRKGILIHTLREENGLPVANCTTPSNGNEREQLIPLIDSTKCENLKTGPST
>NC_008312|5515787:5611019|5565022_5565151_-|WP_081432559.1|DBSCAN-SWA
MNYSNGKFGFSIQKQIWIKLVGKPGIYNVAIADIFIKDIFIK
>NC_008312|5515787:5611019|5608745_5609231_-|WP_011613045.1|DBSCAN-SWA
MQDAITAVINSSDVQGKYLDNDALGRLSSYFQTGQLRVRAATTISANAAGIVKDAVAKALLYSDITRPGGNMYTTRRYAACIRDLDYYLRYATYAMLAGDPSILDERVLNGLKETYNSLGVPIGATVQAIQAMKEVTASLVGPDAGREMGVYFDYICSGLS
>NC_008312|5515787:5611019|5532884_5533385_-|WP_011613008.1|transposase|DBSCAN-SWA
MELELIVDSSEQSRERPKESEKPEKYYSGKKKNNTFKNQIITTPKGTEIVDVIIGERGPLSDINLLNKQRENFKDNQYFQGDKADQGAERTSTPKKKPRKKEMPEEIKEKNQQKVQKRIFVEHVIRLLKIFGIARERFRLKEKSYEKVIMVVCGLVKLRIGALILV
>NC_008312|5515787:5611019|5579818_5582314_-|WP_011613029.1|DBSCAN-SWA
MNDRQNIHNTSIIHGLTKDQVINLRAVGRGNNIKLDTSRSYRQILKENLFTFINTVFLSISLVLISLSRYGDAFLVIIVILGGVIVSVCQEIWAKQKLDQIALLARPLATVIRETKQQNIDPSEIVVGDILVVHSGDQIVVDGQVVGKGQIEVDESLLTGESDLVPKQAGQPVYSGSFCVSGTAHYEAQKVGTESFAYQLTVSARAFRQIYTPLQQEINLVIRVFLLLSCFLWILVSINWYFGFYKFVDTVQYAAVIAGLVPSGLYLAITLAYALGAVKMVGQEVLIQQANAVESLSNVDILCLDKTGTLTTNHISLQAIYPIGIDEIKLENILGEYAASTTSKNKTIEALERVFPRPKRSLTFEIPFASARKWSGMSFATEEQNSPSGTYILGAPEILAEVTPLSRKFTQQIQKLAQKGFRVLLFAYNPNISSLDQDLEKLQLPTELFPLGIISFQDELRPEARETIEGFSKVGIKIKVISGDNPQTVATLALQAGLSSNIQVISGSELAKLDEDQFIQAAKSKTIFGSVTPKQKAKLIHSFKKQGHYVAMIGDGVNDVLSLKEANLAIAMEGGSKATRSVADIVLLNNSFASLPHTFLEGQRIRNSIQDVLKLFMIRVFCVSILIFSTGFIGGFIGGTFPLLNKHSAVVTLISVGFPTFCIPIWAKPGILPRRSMIRSLLHFTLPATFSLTLVALLVYLTYLAIPFSGNELVIDLDQVNEFLSVPRSALVTIMILCGLLLVPFLKPPTKAWVGGETYSGDWRYTFVALALLGVYIVILAVPPLRQFFELSLLSTHDYLVIIWVALVWCLLLRYVWRTKLLDKFLGVDLS
>NC_008312|5515787:5611019|5602598_5605208_-|WP_155994712.1|DBSCAN-SWA
MDVSKLSEMMQRYVEVKQQYSHALLLFRVGDFFECFFQDAVTIAQELELVQTTKHAGKEIGRVPMTGVPHHAVEKYATFLVEKGYAVVVCDQVEDSAIAKKENRQVKREITRILTPGTLTDDGMLKARYNNYLAAVVIAKNYWGLAYTDISTGEFLTTQTEGLDQLTQELMRLQPSEVLFPTKAPDIGFMLRPGERSDHLPEYLPHSFCYSLRPQQPFSLGEAKERLLMKFQLASLEGLGCERLPLGVRAAGGLLEYLEETQKENQVPLQRLRSYTLADFLILDHQSRRNLEITQTVRDGSYQGSLLSVVDKTSTAMGGRALRRWLQQPLLSLKGIRARHDTIDELIQNNDLRQDIQRVLRQIYDLERLTGRTGAGTANARDLVFLADSLTKLPELSTFVSQGNSPYLKVLQKIPPILQELGKKIHSNLVESPSQKLKEGGLIRPGINERLDEMRKLAEEDQKWIASLETTERERTGIPNLKVGYNKAFGYYISISKSKANLAPDDYTRKQTLTNEERYITEELKEREVRILTAQDDLNELEYDIFVDLRNEVGEYAEEIRNVSRAVAALDILCGLADVAIYQNYVRPTMVDSRELKIIEGRHPVVEKYLPAGFFVPNTAILGSKNLEKNNSGITPYSAPDLIILTGPNASGKSCYLRQVGLIQLMAQIGSFVPASSAVLGVSDRIFTRVGAVDDLATGQSTFMVEMNETANILNHATEKSLVLLDEIGRGTATFDGISIAWSVAEYLATEILSRTIFATHYHELNELSSILDNVANYQVTVKELPDKIVFLHQVQPGGADKSYGIEAGRLAGLPDSVIARARQVMQQIENHSKIAIGLRKGINKKEEEEIITVEQLDIFSEEFGDSLL
>NC_008312|5515787:5611019|5610776_5611019_+|WP_011613047.1|transposase|DBSCAN-SWA
MRKDKILSAFPLNFIKKSRSKSFVFINKSGFEDNQDCIYTWSKKGKKVYGEQEEKRGKRENLVAGRRKKEKDLIALIRFK
>NC_008312|5515787:5611019|5542527_5543496_+|WP_011613013.1|DBSCAN-SWA
MEDNANYKNAVDILSTISILKESFSVTEIELFVKLTNFQRYKAKVKIICQSEPAISIICLITGEARVISNDYQLAILREGDIFGESMFSNECIRTANVIASTDVSAIIFTVEDYERLTRISPNIALKYKLFFEAIYKYHKRKDDKFFSVDSTKYLALIAHNEMKSSLVEFVKEHIKLITKFPLVATGTTGLLLHQATGVVLSRKVKSGPLGGDQAIGSMISTDNICGVLFFRDPLSSHPHHADIEALSRLCDVYQVPLATNPSTAKAILLYLDNTPLEGKHNFSLALTKYQENQSRIVHGGVTSSLKPLGDSDYPDIHSVKN
>NC_008312|5515787:5611019|5597284_5598328_+|WP_155994477.1|DBSCAN-SWA
MRKIQESKDKDNIRECLLQNKHIYEYKGEASEEEVLGVDAATAFCDYGEISTALATGVVSSTSENVKPVYKYKAVYGTSSETFSRATNYLRCWSELAALKYATEQDTWVLYDGSFTSINFEMGKWASVMPKEGDISRDFVESELLTDLFVESIKSEDSDWFTVFGDRKLNKVISVGKRGISKYYSTNVIKDFEIEDTAFLPSDKFILGTVLQANEYTKSLSYEQVFVKSHGSGTPGYGHPGLKSEDRFNSMQNDVERTYKNLQILHFKPWPWSPVLKIEYNKERCELNDVLAVIKGQTKTRSILEPMALYLADLLAKQTQSVMNFYGDINTRRYPKLFSAYRTSKRG

Homologous phage analysis in the prophage region

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_011613004.1|5515787_5519246_+|tRNA	isoleucine--tRNA ligase	A0A2P1ELB8	Moumouvirus	2.6e-82	28.4
WP_011613005.1|5519763_5520264_+|transposase	transposase	NA	NA	NA	NA
WP_155994471.1|5524735_5525014_+	cytochrome P450	NA	NA	NA	NA
WP_155994711.1|5525967_5526198_+	cytochrome P450	NA	NA	NA	NA
WP_044136890.1|5526553_5526757_-	hypothetical protein	NA	NA	NA	NA
WP_044136891.1|5528883_5529381_+	hypothetical protein	NA	NA	NA	NA
WP_011613008.1|5532884_5533385_-|transposase	transposase	NA	NA	NA	NA
WP_011613010.1|5537641_5537902_+	hypothetical protein	NA	NA	NA	NA
WP_011613011.1|5538682_5539066_-	endonuclease	NA	NA	NA	NA
WP_155994472.1|5540613_5540817_+|transposase	DDE transposase family protein	NA	NA	NA	NA
WP_044136893.1|5541894_5542107_-	hypothetical protein	NA	NA	NA	NA
WP_011613013.1|5542527_5543496_+	methylglyoxal synthase	NA	NA	NA	NA
WP_011613014.1|5543779_5544061_-	hypothetical protein	NA	NA	NA	NA
WP_011610772.1|5546016_5547054_+|transposase	IS630 family transposase	NA	NA	NA	NA
WP_011613015.1|5547339_5548521_-	tetratricopeptide repeat protein	NA	NA	NA	NA
WP_011613016.1|5550522_5551482_+	glycosyltransferase family 2 protein	NA	NA	NA	NA
WP_044137735.1|5555123_5556713_+	hypothetical protein	NA	NA	NA	NA
WP_044137740.1|5559754_5560492_-	Crp/Fnr family transcriptional regulator	NA	NA	NA	NA
WP_011613020.1|5560799_5561702_+	DALR anticodon binding	NA	NA	NA	NA
WP_011613021.1|5562092_5562518_+	DUF393 domain-containing protein	NA	NA	NA	NA
WP_011613022.1|5563175_5563982_-	hypothetical protein	NA	NA	NA	NA
WP_011613023.1|5564311_5564803_-	crossover junction endodeoxyribonuclease RuvC	NA	NA	NA	NA
WP_081432559.1|5565022_5565151_-	hypothetical protein	NA	NA	NA	NA
WP_155994473.1|5565325_5565544_-	hypothetical protein	NA	NA	NA	NA
WP_044136896.1|5566114_5566417_-	hypothetical protein	NA	NA	NA	NA
WP_044137744.1|5567155_5568295_-	magnesium chelatase ATPase subunit I	NA	NA	NA	NA
WP_011613025.1|5568996_5569824_+	4-hydroxy-tetrahydrodipicolinate reductase	NA	NA	NA	NA
WP_011613026.1|5569826_5570786_-	hypothetical protein	NA	NA	NA	NA
WP_011613027.1|5571977_5572649_-	hypothetical protein	NA	NA	NA	NA
WP_011613028.1|5574670_5575789_-	calcium/proton exchanger	NA	NA	NA	NA
WP_011613029.1|5579818_5582314_-	HAD-IC family P-type ATPase	M1HXH2	Paramecium_bursaria_Chlorella_virus	1.1e-34	26.2
WP_081432478.1|5583928_5584057_-	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_044136897.1|5584505_5584691_+	hypothetical protein	A0A075DXC6	Acinetobacter_phage	7.6e-05	53.8
WP_155994474.1|5591121_5591316_+	hypothetical protein	NA	NA	NA	NA
WP_155994475.1|5591376_5591583_+	hypothetical protein	NA	NA	NA	NA
WP_081432560.1|5592153_5592462_+	hypothetical protein	NA	NA	NA	NA
WP_081432481.1|5593047_5593380_-	ParB/RepB/Spo0J family partition protein	S5WII0	Leptospira_phage	1.9e-06	33.7
WP_155994476.1|5593510_5593726_-	hypothetical protein	NA	NA	NA	NA
WP_081432482.1|5593822_5594032_+|transposase	DDE transposase family protein	NA	NA	NA	NA
WP_011613037.1|5595811_5597071_+	ParB-like nuclease	K4HZA5	Acidithiobacillus_phage	4.4e-11	29.0
WP_155994477.1|5597284_5598328_+	hypothetical protein	NA	NA	NA	NA
WP_011613039.1|5598329_5600006_+	ATP-binding protein	NA	NA	NA	NA
WP_011613040.1|5600691_5601420_+	hypothetical protein	NA	NA	NA	NA
WP_047165189.1|5601721_5601922_+	hypothetical protein	NA	NA	NA	NA
WP_155994712.1|5602598_5605208_-	DNA mismatch repair protein MutS	A0A1V0SJ67	Klosneuvirus	9.7e-45	23.6
WP_011613044.1|5606665_5606869_-	photosystem I reaction center subunit XII	NA	NA	NA	NA
WP_011613045.1|5608745_5609231_-	allophycocyanin subunit beta	NA	NA	NA	NA
WP_011613046.1|5609419_5609905_-	allophycocyanin subunit alpha	NA	NA	NA	NA
WP_081432483.1|5610510_5610744_+	hypothetical protein	NA	NA	NA	NA
WP_011613047.1|5610776_5611019_+|transposase	IS630 family transposase	NA	NA	NA	NA

Sequences of DBSCAN-SWA_9

Nucleotide sequences of DBSCAN-SWA_9

>NC_008312|5699407:5783757|DBSCAN-SWA
AATGAAGGTCAAATTTTTGCAAAAAGCTACATCAAGAATATTAGCACTAGGGATAGGAGTAAGTGTAAATTTCACTAACTTTTCTGTTGTCAATGCTCAAATAAGAGCAGATAAAACTATAAAAATTCGGTACAAAAACCAAATAGAATCAATATTTGTTCAGAGTATAGAAGAACAAACTAATATTCGTGTTTATCAACAAACAAATCAAGCAGTAGTCTCCATAGATACAGATAAAGCAAACGGTAGTGGTACGATTATTTCCCGCGATGGAATGGTACTAACTAATGCTCATGTCGTGTCCCAAGGTGGTATTGTAAAAATCACTTTAGCAGATGGAAGAAAAGTTGAAGCAGATGTCATAGGTTTTGGTGAAAAAGGTTTAGACTTAGCAGTTCTAAAAATTAGAGGAGAAACAAATCTTCCTACCATTAGGATAGCTAGCTCTGGTGATATAAAAGTAGGTCAGCGAGCTTTTGCTATAGGTAATCCTTTTGGTAGATTTCAAGGTACTCTTACTGTAGGAATAGTTAGTCGTATAGATGAAGAAAGAGGTTTGATTCAAACAGATGCAGCTATTAATCCTGGTAACTCTGGGGGACCATTGTTAAATAGTGCTGGAGAACTCATCGGTGTTAATACTGCTATACTTACTCCTAGTCAATTAGGGGGTAATATTGGTATTGGCTTTGCTATATCTATAGATAAAGTCCCAGAGTTGCTCAAGGCAGTTCGAGAAAGACGAGCACCTTTAGTCGCTCAACATTCAAGAAGTAGGATGTTTGATGAGGACTTTGCTAAAAAATTAGACTTTGATGCTTTAATTGAAGTTCAAGGCAATTTAGATGGAGAATCTAATGTATTACCTGTAGATAATAGTTACTATGATCTTTATGCTTTTAAAGGTAGAGCAGGTCAAAAAATTTCTATTGATATGAGTAGTAATCAAATAGATTCTTACTTGATTTTATTAAACTCAGAAGATCAAGAATTAGCTCAAGATGATGATAGTGGGGAAGACAAAAATGCTAGGATTATAATTATATTACCAAAGGATGGAACTTATAAGTTATTAGCAAATTCTTATGAAGCAGGAGAGTCAGGAAAGTATGAGTTGAAAATTGAAGCAATTTCACCTAAAATGAGAATTTTATTTGAGCAAGAAAAGAGTAACTTTTATAGATAAATTGGATGATTTTTTCTCGAATACTTATTTATTAGGAAGAGAATATAACATTCAGAGAATAGAGTGGAGGTTGATTACTGATACCCAGTATCTCCATTGATGATTTTTTTTCAAGTTATAGCTATTGTTAAATAAATGATTGCGGGATAAGAAGATTATACTTTTAGTTTTAGATTTTATCTCAACTAAAAATATAATATATAGAAAAAATTTAATATATAATATATAGAAAAAAAATTTATAATTAACTAAGTTACGATAAATTTTTTCATAATTTGATTTTTAATAAGACTTAGGTAAGCATCTAAAATTATACACAAGAAGTATATGTTAAGGTTGTTCCCTCTACTAGATAAAGTGATGGATATGTATCCCACTTTTATTCATATTTAAACATTGATTTTAAACTCTGTTCTACTGATGAAGACAGTGTACCTATTGTGTAATTATCTTCATTGAATAACTTAATTTATGTTGAATGTTATTTTTTCCAGCTTATAATTACTAGGCTTATGTATAGGAATATTTTTAATAATTGTTATACATACTAACTAAAATCTTCAATAATGTTTTTTAGTTAATAATTATTTGTGGTTATTTCCTACTATGCTAGTAGACTAGTTGGATAATTTAATTAATATATTTGAGGTGATTAATGCATCAAACAAAATTTTGGGCGATCGCTCCTTTTGGTCTACTAACTATTTTGGGAAAACCTTTACTTTCCCCCGCACTTCCAATTCATCAGGCCGTTGTTAATTTTAGCTATGTAGATGAAAGTTCAACGAAGTCTGAAATTTTTGCCCAGGATACTTCATTTCCCAAAGTGACTCCATCACCAGAAATGACTCCGACTTTAGAGGACAGTCCATCACCAGAAATGACTCCGACTTTAGAGGACAGTCCATCACCAGAAATGACTCCGACTTTAGAGGACAGTCCATCACCAGAAATGACTCCGACTTTAGAAGACAGTCCATCACCAGAAATGATCCCTCCCACCCAAGAACCAGAAATAATCTTACAGCAACCAGGAATGCTTAGTGATGATGATTTAGTACTTCCATCTGATGAAAGTGTTTACGATGAACATACTTTTGAAGGGACAGAAGGTCAGGTAGTAACTGTAACTGTAGAAAGTCCTGATTTTGATACTTACTTAGCAGTTTTTAGTCCTGATACTAAACTACTGGGAGAACATGATGATATTAGTAAGAAAAATACAAACTCTCAACTAACAATTACTTTACCTATGACAGGTAAATACCGTGTAATAGTTAACTCTTACGATAAAACAGGTAGAGGTGAGTATAATTTACAAGTAATTCAATCAGGGCAAACATCAGATTTTTGAAGTTCTTCCCAAAGAAGCGTATTATTTACTGAATATTTTTGGCGTTGCTGAAGACAAGGGCTGAAAATAAGATTTGCTCTTCAAGCACTTTTTCCCTGCCAAGATCATGTTCTGTTGAATACACATAATAAAAGTTTTGTGTACACAAGTGTTGCTAAATTTATTCTGGGATAAGCTTTGTGGTGATTTATCATAATTAGATCTCTCGGAAAATTAATCTCAAATTTTTAAATTTACTAGGCTAAAACTTAGTTTACCCAGAGATCTATTTAATTCTGGTCAATGATAAGCACTTAGGTGAGAGCGATCGCGATGATCTAAAAACATCCTTACTCTAAAAGTAGTACGATCATATTTTTTTTTTCAACAACATTTTCACCAAATATTATTTTATCCTATTTGCTCTCTTTGTGCAACAAAGCTTTTGACTTGGTAAATTGAATTAGTAACTTGCTTGCTTTACAAGGCGATCACTACAGCTTTAAGTACGCTTTTGGTTAAACATTAGATTTTCATCATCTCACCAAAACTATTGAAAATAAAACCATAAGGATATATCAAACAATGGATAATGATTTAAATATTCAGGTTGTACCTGTAGAGTTAGAGAATGGCAATGTAGTAAGAGTTGAAGCTACTGTTCTTAATGCATCAGGAGATACTTCTGATCAAGAAATTGAATCAGATGTGGCAGCTAATATCAGACCGCTCAAAGAAGTAACTGATACAGTAAAGGAAATTGCTGCAACTGTGAAAGCTTCCATAGATCAAGTTAAACCAACTAAAGCTTCTGTTGAATTTGGCTTAGAATTTGGTTATGAGTCAGGAAAGCTAACAGCTATGATCGTGAAAGGAACGGCAAAAGCAAATCTAAAAATTACTCTACATTGGGAAAATATTTCAAAATGAGGAATAGTATAGATGCCGGACGCTTGTACGAGTTATTTCGTAGTTGCATAGTACGAATTAAAACCTCAAAGAGTTTTGGTACAGGCTTTTGGGTCACTCCTGGACATATTCTTACCTGTGTTCATGTTATTGAGGGGAATGATCACGATAGTATTGAAATTGTCTGGAAGCAAAATAATTATCAGTGTACAGAGATTAATATTTTTCAAGATGCTGACCTGGCTTTACTTAAGGTTGAAATAGAAAGTCATCCTTGTGTGTTTTTGGATGAAGACGCTTTACCAGGAGATGAGCTCTATAGTTATGGTTATCCTGAGCAAAAGCGAGATGGGGCTTCAATTACAATGATTTGTGAAGGGCCTACAGATAATAAGAGGTTTTTGACGGTTAAGGATGAGAATGTTAGACCTGGGTTTAGTGGCGCTCCTTTATTTAATCAAAGAACGTTCATGGTTTGTGGTGTGCTCAAGAGTGAACGTAAGTTTCCTGTTAATGGTAATGTACTACGGGCTTTGGGTGGACAAGCAATTCCAACTGCGAGAATTTTTGATAAGTGGCCTAATTTAAAAATATCTAATCAGGAGTTCCATCAAAAGTATCAAAGTTGGAGAAAAGAACTGGAAGTAACTAAACAGCAAGAACAAAATTCACCACAATATTCGGCACAATATTCTATAAATAGTTCTTCTGAAAATCCGAGAATTCAATCTTTAAAAAATCAGAAACAAAGAATAGAGTCTCAGATAGCTGAACTAGAAAAACTAAGTCATTTATGTAATCAAGATATAAAGGCAGAAACTAATTTGGCTAAAAGAAATCAGCTTCATACACAAATGGATAATTATTCGACAGAAATTAACGAGTTATATGACAAGGTTCAGCAAATTATAGCTCAAATTAATAAGTTTCAAAATACTTAGTTTATACAAGTAATTAAAAAGTTATTTAAATGTCAGATATTCAGAAATTAAAAAGTTTAGAAAATCGGCAACAAAGAATAGAGTCTCAGATAGCTGAACTAGAAAAACTAAGTCATTTATGTAATCAAGATATAAAGGCAGAAACTAATTTGGCTAAAAGAAATCAGCTTCATACACAAATGGATAATTATTCGACAGAAATTAACGAGTTATATGACAAGGTTCAGCAAATTATAGCTCAAATTAATAAGTTTCAAAATACTTAGTTTATACAAGTAATTAAAAAGTTATTTAAATGTCAGATAGTCAGAAATTAAAAAGTTTAGAAAATCGGCAACAAAGAATAGAGTTTTAAATAGCTGAACCAGAAAAATTAAGTAATTTATCTAATCAAGACATAAAGGCAGAAAGTAATTTGGTTAAAAGAACTCAGCTTCATACACAAATGGATAATTATTCGACAAAAATTAATGAATTATATGATAAATTTCAGCAAATTATAGCTCAAATTAATAAGTTTCAAAATACTTAGTTTATACAAGTAATTAAAAAGTTATTTAAATGTCAGATAGTCAGAAATTAAAAAGTTTGGAAAATCGGCAACAAAGAATAGAGTTTTAAATAGCATAGCTGAACCAGAAAAATTAAGTAATTTATCTAATCAAGACATAAAGGCAGAAAGTAATTTGGTTAAAAGAACTCAGCTTCATACACAAATGGATAATTATTCGACAAAAATTAATGAATTATATGATAAATTTCAGCAAATTATAGCTCAAATTAATAAGTTTCAAAATACTTAGTTTATACAAGTAATTAAAAAGTTATCTAAATGTCATATATTCAGAAATTAAAAAGTTTGGAAAATCAGAAACAAAGAATAGAGTCTCAAATAGCTGGACTAGAACAACTAAGCAATAAATGTAATCAAGAGATAAAGGCAGAAACTAGTTTAGCTCAAAGAACTCAGCTTAATACACAAATGGATAACTATTCGACAGAAATTAATGAACTATATAACAAACTTGATCATATTGAAAATGAAATTGAAAATCTCAAGTTAAAGGAGAAAAGTTTGAGTTCAAACGATTATTTAGACAACCCTAAAAATCAGCAATTATTAAAATTTGAGCAATACTTGTATGATATCGATTTTGAAAAAGCTTTAAAAACTTTTCAAAGAATTACATCTCAGTTTAATAAGGAGGGAGATGTAGCTTTGTTTTTCATAGAAAAATGTTTGACTAATCGAGGAGATTTATGTTTAAAAAGACTAAAAGATGACTTATTTTCAGAGACTTATAATATTCACAGGCAACATTTTCGTCCCTGTTTTGTCACATATACTTTAGGAAATTTAGAAGGAGTAATACAAGGAATAGCTAAATTTTTTGACGTTAAAAAAGAAGAAATGACTGTAGAATTAGTTATCAATAAAATAGGTAATTCTTTACAAAATAATTCGGTTTTGTTTATAGAAATTAATTGTGATATTAGTCAGCCTAGTGACATAGATCCATTAATACCTTGGTTTATTAATGTTTTTTGGAAACCTTTGAGAGAAAAAGTAAACGAAGTAGCTAAGGATTATGAAGGTATTAAAGTTGTAGCTGTAATAACTTCTAATCTATTACTTAATTCCAGATTTTCAAACTCAGAATTATCCTCCTACTATAATCGCAAAAGTAGAATTTTTTCTAGAGATAAATTAGTCAAAATACCTTTAGAAAAATGGAAAAAAGAAGATATTAAAAAATGGTTGACTAAATATGGTAATCCTCGTTTAAAAAACACAGATAAAGATACTATAGCTGAAAAAATTTATAATGCAACTGACAAAGGAAGACCTACAGATGTTTGCCTAGCTTTACAACAAAAACAATGGCAAAACTTAATATATTCAAACCCTACCTATTAAACAATTATAAGTTCAAAGATGAATTACCATTTTGAAAATAATCCTAAAAATCGTCCTTCTAAACCTCATTCTGATTCACCTAAAAAAGTTGAACCCTACATTGCGCCAGATGAGTTAATTGATGCAGTAAACTTAGCAATTTTTCTGCGCCGTCCTCTCTTATTAGAAGGAGAAGCAGGCTGTGGAAAAACTCGATTACCACTCGCAGTTGCTTATGAATTAGGATTACCTTTTTATCGTTGGAATATTCGTTCAACTGCTAAAGCACAAGAAGGTTTATATGAATATGATGCTATCCTCAGACTCCATGATGTTCAAACTCAAAAATTAGAAATAAAAAATAATAATCAAGACAAAGATAAAACTTATAGAAATCCTAGTAACCCTGAAAATTATCGAACTTTTGGAGCAATTGGTAATGCTTTTCTTTCAAATTGCCCGGCAATAGTTTTAATTGATGAAATAGATAAAGCTGACGTAGATTTTCCTAATGATTTACTAACAGTTTTAGATGAACCTTGGGAATTTAAAATTAGAGAAACTGGAGAAACAATTACCGCTAAAACTAATTGTCAGCCAATTGTAATTATTACTAGTAATAAAGAAAAAGGAAACTTACCAGCTCCTTTTCTACGTCGTTGTATTTATTATTATCTGAAATTTCCAGATGACCCTAAACAACTTCAAAAAATTGTTGATATTCACTATCAATATAAACCAGACTCAGAAATTCTCAAAAAAATTAATTCCTCAAATAATGAATTAGTACAACAAGCTGCTCAACTATTTATTAAAATTAGAGAAAATAAAGGCTTATTTAAAATTCCAGGTACAAGTGAATTTTTAGATTGGTTATATGCACTTTGTAGTTGTCAGACAAAACAAAATCCTCAGCTTCCTTATCCTCTTGAGAAATTAAAAGAAGGAGAATTAATTCCTTATCGAGAATTAATTTTTAAAATTCGTCAAGATTGGCAAAAAAATACCACTTTTCCTCAAACTAGTGATTTATAAAATATCTCAAACTTCAACTTATTTGAACTACATTTTATTCACTTAAGCACAAAACTTTCAACCACTCATGTTTGAACCTAACTCTTATTTAACAACTCTTTTTTATCATTTGCGTCAAGCAGGTTTTAATCTGAGTATTAAAGAATACTTTTCGGTAAAAGATGCAATTAAAGGAGGTTGGGGAACAAAAAATCAAGAAGACTTAAAAAAACTCCTACGCTTACTATGGTGTAACTCTTGGGAGCAACAACAGCATTTATCCCTAATATTTGATAGGATTTTTGAATCTGAAAAAACTCAAGAAACAACACCAAACCCCTCCACAAAAAATCAAAAAAATTTAAATTATGAACAACTTGAATCAGACTCATCAACTCCTATTTCTCCTACTACAAAATTTCAATCTTCTTCAACAGAAATAACTAAACCAACCACTGAAAAACTATCCCCACTACCTATCACTAATATTCAACCAATACGAGAACATGAAAACGACGCCGAATTTTATACTTATTATCCCATTTCTCGCCGTTTTATGGTTTATAGTTGGCGATATTTACGTCGCCCCATTGCTGACGGACTTAGAGATGTTTTAGATATTAAAATGACTGTTGAACAAGCTACAAAACAAGGATTTTTCTTACAACCAGTCTACCGTCGACGAGAAAAAAATCATGCTCATTTACTAATTTTCGTAGATCAAGAAGGTTCCATGACTCCCTTTCATCATTTCAGTCAAGACTTAGTAGAAACAGCTAAATATGAAAGCTCTATAGAAACAGTAGACGTTGCTTATTTTCATAACTTACCAGCAAAATATATTTATCAAGATCCTTTTTTGACTGATAAAATTTCCTTAGAAACTGTCTTAAATAAATGTGATAGTGAAACTAGAATTTTAATCATTAGTGATGCAGGTGCTGCTAGGGGGTATCGTCAGCGAACAAGAGTTTCAGGCACAACTGAAGTAATATGGGAAATTCAACAGCATACTAACTTAGTAGCATGGCTTAACCCAGTTCCAAAAATGCGTTGGAATAACACTACAGCTAGTATTATCTCTCATTTAATACCTATGTTTCCTATGGATCAAGAAGGTTTAAGACAAGCTATTTTGACTTTACAAAGATAATATAGAAATGACAGAAATAACAGATAAAATTATCGCTCAGAATAAAGTAGAACAATTTGTAAGTCGTTTTGAAGATTCCTATTTCTTATTAGCTTCCCATGTCGCTTTACCTCTAGTATTAACTCCAGAATTAGTCAATTATCTCAGAATTGAATTTCTCAAAAGTGAAAAAGTTCCTTGGATTTCTGAAGCTGATTTATTGTTATCTAATTTGTGTCGTCCAGTTGGTTATGAACTTTATGTAATGGATGAAGGAGTAAGAATTTATTTACTCCAAAAATTAGCAGAAAACCCAAAGTTTGGTCAGAAAAGAATTAAAGAAATTGCCCGTTTATTACTGAGCTATATTAAATATTTAGCTAAAACTAATCATTTTATTGGAGACAAAGAACTACAACTTCAGACATGGGGTGCAATGTTGTATTTAGATACAGAGAAAACTGTCAAGGAAATAGCTTTTGCTATCTCTCAATGTATAGATAAAGCAGAGTTAGCTCGTTTACTAAAAATTACCCAAGATTTTAAACAACAAATAGCTTCATCAGGACAATTTCAAGACTTTTTAGACTATGCTCAACTTTGTAATGAATTACTTAGAGAACCTGAAAAAGTAACCCTAGAAAAAATAACACATTCATACCAGGTCGCAAAGCTTGAATTAACTATACCAAAAATAGTTTTATCAAAAGAATTAGATCTAGGGGAATTATTTTATTTTGAAGTTGTAAAAGTTGATAATTTTGGCAATATTATTGAGCGTAGTCAGGAAAGCGCTAGGCAGAAAATAGAATATTTGGGTAATGAAATTAAATTGGAAATGGTTTATATTCCTGGGGGTACTTTTACCATGGGTTCTCCTAAAAGTGAAGTGGATAGCAGAGATAATGAACGGCCCCAACATCAGGTAACTGTTCCTTCCTTTTTTATGGGCAAATATCCAGTAACTCAAGGACAGTGGAAAGCGATCGCCTCTCGAACAGAATTAAAAGTAGAACGAGACCTAGACCCAGAGCCATCATATTTTAAAGAACCATACGAAAGTATAGATAGATGGCAGAGACCAGTGGAGCTGGTTAGTTGGAACCAAGCAGTAGAATTTTGTCAAAGACTATCAAAACTAACAGGAAGAAAGTACAGGTTACCCAGTGAAGCCGAATGGGAATATGCTTGTCGTGCAGGAACGAGTACACCATTCTACTTTGGAGAAACCATAACATCTGAGTTAGCTAACTATGATGGCAACCATACTTACGGCAAAGGGCCAAAAGGAGAAAATAGAGAGCAAACAACTCCTGTAGGTAAATTTCCACCAAATGCTTTTGGTTTATATGATATGCACGGAAACGTTGATGAATGGTGTGCTGACGACTGGTATGATAATTATGTAGGAGCTCCTACAGATGGAAGTGCTAGGATTAATAGTAATAAAAATAGTAATACTAATAGTACAAAAGTATTTCGTGGCGGCTCCTGGATCTACTATCCTTGGTGGTGTCGCTCTGCGCTCCGCGGCAACTTTAACTCGGACGAGGCGGACAGCATCTCTTTTGGTTTTCGTCTTGTGAGTTTCCCCCCCAGGACTTTTGAATAGCCCTTTGCCCTCTTGCCCTCTTGCCCTATTTAGTCTCGCCTTTGGCGAGCCGAATTTTTTTGAGAAATTATCAAATGGCCACCAAATCAATAGATTTAATAGATATAACAATAGAAAAAAGCTCAGAACACTAAATTATGCAAAATTTTGTTTAAAAGCCGAAATTAATGACTTAAACTGTGCTTCGACTGGTATCATAAATATGAAGCTTAGGCTCAAAAACCTAAAATTTAGGGCAGGAAGAAAATTCCCAGAAAATTTATCCTCTTATCCCGTAATTAAATAAAGACACCCAGGTTTAAACCCGTAGTCAAAGTCTGGAATGCTAGTGTCTACTTGCAAAAAATAGTAGTATTATTTTTAGGTTGAATTTCCTTAAGTTCAAGTTTTTTGTTTTACCTTAGCAAGCATATTAATTTATACAACTAGATAATAGTGTTGCTTCTCAGGAAAATTTCTGAATACTTGATTATCTCTTACTAACGAATTTTTGTTGAATAAAAAGTCATGTATATAGGCAAGTTTCTCCATCTAATCTTATAATATCACAAAAAAAAATCTGAGAAGGGGAGGAAAGATTTTGCGCCGCGTCGCTTTTTCGGAGCTCCAGAAAATGAAATAAAAGTTGGCGATTTTCTACTGAGGAAGAATAAATGGAAAAATTCGACTATGGGAAAAAAATAGAGGGGTGCTTCACAGAATGAGTTAAATAAATTAGTCTTACTTTTGGGAAAATTATTAAATGCTTGATTCTATTTTCCTAAAAAAAAGAGTTGAATAAAAAGTCATGTATATAGGCAAGTTTCTCCATCTAATCTTATAATATCACAAAAAAAATCTGAGAAGGGGAGGAAAGATTTTGCGCCGCGCCTCTTTTTCGGAGCTTCAGAAAATGAAAAAAAAAGTTGTTGATTTTCTACTGAGGAAGAATAAATGGAAAAGTTCGGCGGTGGGAAAGAATATTGGAGTGCTTCACAGAATGAGTTAAATGAATTAGTCTTGCTTTTGGGAAAATTATTAAATCCTTGATTGTATTTTCCTGAAAAAAAAGAGCTGAATAAAAAGTCATGTATATAGGCAAGCTTCTCCATCTAATCTTATAATATCACAAAAAAAATCTGAGAAGGGGAGAAAAATTTCTGCGCCGCGCCGTTTTTTCGGAGCCCCAGAAGATGAAATAAAAGTTGGCGATTTTCTACTAAGGAAGAATAAATGGAAAATTTCCGCGATGGGAAAGAATATTGGAGTGCTTCAGAACATGAGCTAAATGAGTTAAATGAATTAGCCTTGCTTTTGGGAAAATTATTAAATCCTTGATTGTATTTTCCTGAAAAAAAAGAGTTGAATAAAAAGTCATGTATATAGGCAAGCTTTTCCATCTAATCTTATAATATCACAAAAAAAATCTGAGAAGGGGAGAAAAATTTCTGCGCCGCGCCGCTTTTTTGGAGCCTCAGAAGATGAAATAAAAGTTGGTGATTTTCTACTAAGGAAGAATAAATGGAAAAATTCGGCGATGGGAAAGAATATTGGAGTGCTTCAGAACATGAGCTAAATGAGTTAAATGAATTAGCCTTGCTTTTGGGAAAATTATTAAATGCTTGATTGTATTTTCCTGAAAAAAAAGAGTTGAATAAAAAGTCATATATATAGGCAAGCTTCTCCATCTAATCTTATAATATCACAAAAAAAATCTGAGAAGGGGAGAAAAATTTCTGCGCCGCGCCTCTTTTTCGGAGCTCCATAAGATGAAATAAAAGTTGGTGATTTTCCGCTGAGGAAGAATAAATGGAAAAATTCGGCGAAGGGAAAGAATAGCGGAGTGCTTTACAGGATGAGTTAAATGATCTGAATGAGCTAAATAAATTAGTCTTGCTTTTGGGAAAATTATTAAATCCTTGATTGTATTTTCCTAAAAAAAAAGAGTTGAATAAAAAGTCATATATATAGGCAGGCTTCTCCATCTAATAAGATCACAAAAAAAATCTGAGAAGGGGAGGAAAGATTTTGCGCCGCGCCGCTTTTTCGGAGCCTCAGAAGATGAAATAAAAGTTGGTGATTTTCTACTAAGGAAGAATAAATGGAAAAATTCGGCGATGGGAAAGAATATTGGAGTGCTTCAGAACATGAGCTAAATGATCTAAATGAATTAGCCTTGCTTTTGGGAAAATTATTAAATGCTTGATTGTATTTTCCTAAAAAAAAAGAGTTGAATAAAAAGTCATATATATAGGCAAGTTTCTCCATCTAATCTTATAATATCACAAAAAAAATCTGAGAAGGGGAGAAAAATTTCTGCGCCGCGCCTCTTTTTCGGAGCTCCAGAAAATGAAAAAAAAGTTGGTGATTTTCTACTAAAGAAGAATAAATGGAAAATTTCGGCGATGGGAAAGGATATTGGAGTGCTTCACAAAATGAGTTAAATGAATTAGTCTTGCTTTTGGGAAAATTATTAAATGCTTGATTATATTTTCCTAAAAAAAAGAGTTGAATAAAAAGTCATACATATAGGCAAGGTTCCACATCTAATCTTATAGTATCACAAAAAAATCTGAGGAGGGGAGGGAAAATTTTGCGTCGCGTCGCTTTTTCAGAGCTCCAGAAAATGAAGCCAAAATGGTGATCTCCTCTGAGGAAGAATATGTGAGAGAGAATAGCGGAGTGCTTCACAGGATAAGCCAAATGAATTAGTCTTGCTTTTGGGAAAACTATTAAATCCTTGATTGTATTTTCCTAAAAAAAAGAGTTGAATAAAAAGTCATGTATATAGGCAAGCTTCCTATTTAATCTTATATTATCACAAAAAATCTGAGAAGGGGAGGAAAGATTTTTCGACGCGCTACTTTCCCGGAGCTCCAGAGAATGAAATAAAATGGTTTGTGACTTTTCACTAAAGAAGAATAAATGAAAAAATTCGACTATGGGAAAAAAATAGAGGGGTGCTTCACAGAATGAGTTAAATAAATTAGTCTTACTTTTGGGAAAATTATTAAATGCTTGATTCTATTTTCCTAAAAAAAAGAGTTGAATAAAAAGTCATGTATATAGGCAAGCTTTCCATCTAACCTTATAATATCACAAAAAAATCTGAGAAGAGGAGGAAAGACTTTGCGCCGCGCCTCTTTTTCGGAGCCACAGAAGATGAAATAAAAGTTGATGATTTTCTACTAAGGAAGAATAAATGGAAAATTCGACCATGGGAAAGAATAGCTAAGTGCTTCACAGAATGAGCCAAAAGAATGGGAAAATTATTAAATCCTTGATTGTATTTTCCTAAAAAAAAGAGTTGAATAAAAAGTCATGTATATAGGCAATATTCCCCATCTAATCTTATATTATCATAAAAAATCTGAAAATGGAAGGGAAATTTCTGTAGCGCGCCGCTTTTTTTTTTGGAGCTTCAGAGAATGAAAAAAAATCATTTGTGACTTTTCATTAAAGAGGAATAGATAGAAAAATTCGACTATAATTCTCCCCTTAATTTAAGATATTTTTGAACTAAATAATATCGGTTTTACAGGAGTAATATTATCTGCTAAAAATTCCATATCTTCTAACTTGCCATCACAATATAATGCTAAATCGCAACCTGCTTTTAATGAGCGATTAACTTTCGTAACTAAATCTCCTGATAAAGCCTTCATAGTTAAGTCATCAGTAACTAATATACCTTCAAAACCAATTTGCTTACGGATAATTTCTTGTATAATAGTAGGTGAAACAGTAGCACAATTTTCAGAATCAATAGCAGTATAAATAACATGAGCGCTCATGGCCCAAGTAACAGATTTTGCTAAAGCTTTAAAAGGTAAAAAATCACATTCAGATAATTCTTTTAGAGAAGTTTCAACCACTGGTAAAGCTTTATGACTATCTACTAAAGCACGACCATGACCGGGGATGTGTTTAATTACAGGCATAACTCCTTCCTCTTGAAAACCTTCAATAACAGCTTTAGCCATTGTGATAATTTCTGAAGGTGAATTACTATAAGCTCTTGTACCAATTACTAGATCCGCTTCAGGTATAGGACAATCAAGTACAGGAGAACAATTAACATTAATACCAATGTTTTGTAAATCTTGAGCTATGTGTTTAGCATCTATTTTTGCTCTATGTGCAGCATCATTAAGATCATTAATTTCTTGAAGATAAGAGGAAGCAGAAGGTGCAACCCACCAATGGGGAGGCTGTAAACGAGCAACTCGACCTCCTTCTTGATCAATTAAGATAGGAATGTCTTTTTGGTTAATACATTTTCTCAAAGTATCAGTTAATTGTTTAACTTGAGTAGGGTGTTCACAGTTGCGTTGAAATAGAATAAAACCAGCAGGTTGAGAGCGAGTAAATAATTGTTTTTCAGCCTCAGATAAAATTGTTCCAGCGAGTGAAAAAATTATAGGTAACATATTTGTTTGAGAATTCGATATAAGAAAAGAGTGCTTGAAAAGTTTAAATTATCCCTTTAATTTCCAAAATTCAACCTGAAAAGCTCCTAATTTTTTGATAATTTTAATCAAAGATTGATAGGTTTTTGTGTCATGTTTTAATAATCTATTAGTTATAGGTGCTAGTGGTTTAGGAAATTGGTAATATATTAGTAAGAAATATTTGATATTTTGTTGAAAATAAGTCTTACATATATCATCTTAGTGTAAATTTAGAATACGAAAAAATAAGAAACGTTCGACCATCAAAATATTTCCTTTTTCCGTCTTATTATGATCATATTAGGATCAAGATTTTAGTACATCAAATACTGAATCTTTTGAAGGATTATTAAATGGATGATTTCTATCCTTCAGTTTTCAGAAGGTAGATGAACAAAATAACTACTTTTTTAGTGCTACCAAAAACCAAAAAATATAAAAATTATTGCTTGCTCCCAGTAAATTTATTATCTAAGCTTTTAACTGATTCAATCAGCGATCGCACAGTTTCAGTTCCTTGAGAAGGTTCAAAAATCAAAGGAAACTTACCTTTAGCCAACATCCTTAATCCTAAAGGGCCCAAACTATATAAACCTTTAAGATCTCGAAAATAATTACCCACTACTTGAATACCAAATTTTCTTTCATCAATCCAACCTCCATTCTTAACCAAATCAATTAAAACTTTTCGGTGGCGAATAGAACGACTAGCTTGTTGATCTTTACGAGCCAGAACCTCCTGCTTAATCTTACCTATTTGATCCATAGGTGAAACTTCCATGGGGCAGACAGAATTACAATAATAACAACGAGTACAGCCCCAAACTCCAGCAGTATCAAGATTATATTTTTCTAATCTTTCTGTTGTTTGGTTGTCCCGTGAATCAGCTATCATCCTATAAGCTTTCCCTAAGGCGTGTGGCCCTACAAAATCTGGATTTACTTCACGAGCATTACATTCAGAATAACAAGCCCCACAGAGAATACAATTACCTGTTTGATTGAGTTTATCCCGTTCACTAGGAGTCTGTAAAAATTCCCGTTCTGGAATCTTTCGTGCTTCTGTACTTACATAAGGTTGAACCGCTTCTAGATTTTGCCAAAAGCTGTTCATATCTACAATCAAATCTTTAATTACTGGCATATTTCCCATAGGAGAAATAGTGATTTCTGGAATAGATTTTACAGTAGTATTGGTGACATAATCATGATGATTGTTAGTTGCTATTTTTTCGAGTCTAGCTAATTCATTTCTAATATTTTCTTTGCAAGCTAAAGCTGAACGACCGTTGATTCGCATTGCACAACTACCACAAATAGTATTTCGGCAGTTTTTCCTAAAAGCTAAACTTCCATCTTGCTCCCACTTAATCCGGTTTAGGCATTCTAAAATTGTATTGCCTGGTTCAATTTCTAGGGTGTAACTTTGAATTTTTGGCTGAGTATTTTGATTTTGCCTAACAATATTAAAATTAACTTTCATAAGTAATAATTTTACTGAAGTTTTCTATACTATCTAAGTTTTAGTTTAATTATCTTTATTCTGCATTCTGTTAAAGTTTTTTCATAACTTATGCAAAAACTATATATATGAATTAAAGTTTTTGCCAATTATCTTTCATAAGTTAGGTTAATTAATCAGTTTTCAAGCAATATTAATCACTTGCTATATTTACTTTCTCCTAAAAAATGACTATTTACAGCATATTTCGGGTCTATAAGGTACAAGATGAATACTGAAAATTATATAGCACAGGTATCTTGCTCACGTTAGTGTACCTTATCAGAATGTCAAGTTCTGTATATACCACTAGGAAATTAACAACAGTAATTTATAATAGAAAAACAGTAAATAAAACATTTATACAGCATATTTCGACCATATAACTGCAGGGTAAATATTGAAAATTATGTGTTGCAGGCATCTTGTCCGCCTGGGTGTACTTCATAACAAGGTCAAGCGCTGTATTTATAGCTGCATTTAAAAGGCACAAAGTCACAAGTCAGAAGGCGCAAAGTTAAATTTGTAGCAAGGACTAAATTTGAGAAGTGGGAGATTCTCTTGATAAGTGACATGGTAACTGTTGTAAATATTGCTAAAAAGACAAAATAATTGAAGCAGATAAATATAACATAATGAGAGACTATATTGTACCCCAATTGCCAAAAGCTCCTCTATCTCGTCGTGCACTAGCATTCAGTATAGATGCAGGAATAGTTTGGTTCCTTAGTGCCATTATTAGTAATAATTGGTTCACATTTATTTTATTTTTTGTGGTATTTTGGATAGCTATACGAGTTGTAATGGTCTACAAAAATCAAGGTCAGAGCATCGGCCATTTTGCTCTGGATATGAAAGTTTTAGATAGTAAGTACCAAAGAGCTCCTGATATCCTAGAATTATCAAAGCGAGAAGGAATTTTAGCACTAGCTGGATCATTAGCAATGCTAGGCATGAGTAATTTGACATCTGGAAATGCTGCTGTTTTACTACTAATAATGCCCTTGTTTTTAGATTTTACAGTAGCTTTGGTAGATATTGAAAGGTATCAGCAAGCTTTCCATGACAGAATATCTCATACGATAGTAGTGGGAACTATGCGTGGTTATTCCCTAGATATTAAGCTTAGATGGTTACTTGACGAAGCCAAGCGTTATATGATAAAATAAAGTTTTGGTTTGTGTTTAGCATTAATGGAAAGTGACATATGGCTAAAGGAGTAAGAATTATTATTACACTAGAGTGTACAGAGTGTAGAACTAATCCTAATAAACGTTCACAAGGTGTTTCTAGGTACACAAGTACTAAAAACCGTAGGAATACAACATCAAGATTAGAGTTGAAGAAATTTTGTACTCACTGTAATAGACATACAGTTCATAAAGAAATTAAGTAAAAATTTAGTGAGTATTAAACTATAGTAAAGTGCTTAATAAGCTATAAACAAAGTGTTAGGAGTTTGATACAATTTAGACTTTTATAGGTAAAAGTTTTGATTGATATGAATTCTGAATTAAGTTAAAACGTAAATAAAAATTATTAGCAGATAATACGCGCTATGGCAAATTACTACCGGAAAAGAGTATCACCTATTAAACCAGGAGATCCCATTGATTACAAAGATGTTGAGTTACTCAAAAAATATATTACTGAAAGAGGAAAAATTATGCCAAGAAGAATTACAGGTTTAACATCTAAACAGCAAAGAGATTTGACAAAAAGTATTAAAAGAGCCAGATTAGTGGCATTATTGCCTTACGTTAATAAAGAAAGCTAAGGCTAGGACTGTGTGAAATTTCATAATGTTGGGAAAAATGATCAAGTCTTTTGAGTGAGGCATCTAGTTAAGGAATAGTTGAGCATTTAAGGGCTGAGGAGTTGTCAGCTCTTGAAATAGAGAGCTGAATTATCAAACAAATAATTGATTGTAAAAATTATTATAAAGGTTAATTTTTAGTTAAGATTTAAAATCTTTTGAGTTAAGAGAGACCAAATGCTAGCAAAGATGAATGGGCAAGGGGGCTACTCTTAAGATGGTAAGAGCCATTACTTTAATCAGTGATGCTACATTGATTCAACGTGCAGAGCTTTGAGTAGGTTGAAGATTGCACAAAGCTCAAGAAAACTTAAACTATATACATTAAGAGCAAGTGGAGAAGGGAAAATTAATAGAATTTAGACTGCACGGAGAGCGTAGACTAGCTGTGGCAGATCGTCCAGACGGTAAAAAAAATTGGGTCGTGATAGAAGCAAATGGTAAGTCTAATAGTATACCCCCAAAGCAAATAAGTTATGAAGTAGGAGGAGAAAGTTATCAATCATCAGAAATTCCCCAGTTTATTCAGGAGGTAAAAACTTACCTGGATCCTTCTAGTTTAGAAGTAGCATGGGAATTGCTAGTAGAAGAAGCAGAAGCAGTAAATCCAGAAGAAATGGCCCTATTGCTATTTTCAGAACAAACACCGATCCAATGTTATGCAGCTTATATATTATTATCGGATGATAAACTCTACTTTAAGCAAAAAGGCGATCGTTACGAACCCCGCTCTGTAGCCCAAGTAGCAGAAATTAAACATCAACAAGAAGTCCAAAAACAACGAAAAGAAGAATTAGAGAACTTTTTACTGCGGGTGCATAACCGACTAGCAGGGGAAAAGGTAGAATGGGAACAAAGTGATTATAACCGCCTAGACATCATAGAAAAATTTGCGACTCATGGAGAAGAAACTTCCCATCGTAGTCAGGCCATGGAAACTTTGGCTACCTTAAAAGTACCAGAAACTTCAGAAGCAGCATTTAAACTATTAGTGGATCTAGGTATATGGAGTGAGCATGAAAATCTATATTTGCGACGTAGCCAGATCCCAAAATGTTTTTCTACCAAGGTACTAGAAGTGGCCAAAAGCTGCCTGCAATCCCTCCCACCAGATCCAGAAACAAACCGTTTGGATTTAACTCATTTAAAAGTCTATACAATTGATGATGAAAGTACCCAAGAAATAGATGATGGCCTGAGCATAGAATTTTTAGAAGATGGTCAACACAGGATATGGGTACATATAGCTGACCCAACTCGTTTACTTATTCCTGGTGATGAGTTAGACCTAGAGGCCAGACGCAGAACGACTACTTTATATTTACCTACTGGTATGGTTCCTATGTTTCCCCCAGAGTTGGCCACAGGGCCAATGAGTCTAATTCAGGGACAAGTGTGCAGAGCTTTGAGTTTTGGCATTCTTTTAGATGAAAGTGGGGCAGTTATAGATTATATAATTCATGCCAGCTTAATCAAACCGACTTACCGTCTTACTTATGATGATGTGGATGAAATGCTACAGTTGAAGATTAAGCTAGAACCAGAAATTCATGCTCTGAATGATTGGGCTAAACAAAGATTTAAGTGGCGACAGTCACAAGGCTCGATTAGTATTTATATGCCAGAGTCGGTAATTAAAGTGAAAGGTGAAGGTGAAGAAATTACGGTAGAAGTATTGGATGATTCACCTTCAAGACAGCTAGTAGCGGAAATGATGATTTTGGCAGGGGAAGTGGGGGCAAAATATGGTCAAGAAAATAATATTCCTCTACCCTATCGTAGTCAACCTCAACCTGAACTTCCACCAGATGCAGAACTAATGTTGTTGCCAGCAGGACCAGTTCGTTCTACAGCTATGCGTCGATGTATGCCTAAAAGTGAAATGGGTACTATACCAGCTCGTCATGCAAGTTTGGCTTTAGAAACTTATGTTCAGGTTACTTCTCCTATTCGGCGTTATAGTGATTTATTGGCCCACTTTCAGATTAAGGCTCATTTGCGGGGTGATCCGTTACCTTTTACTCTAGAACAAATGCAAGAAATGGTAATGAGTTTAGTTCCGGCGGTGAAGGAAGCTTCTAGTGTGGAAAGGTTTACTAACCGTTATTGGGGTTTGGAATATTTACGCCGTAATTCTGGTGAGGTTTGGCAGGCATTGGTAATTCGGTGGTTGAAAGAAGAAATTAATTTAGGGTTGGTGTTGTTGGAAGAGTTGGGGTTAGAGTTGGCTATGCGGTTTGGTAGATCAGTTGAAGTGGGCGATCGCTTAGAGGTAAAGGTTGCTCATGCTGACCCTCGTAGAGATGAGATTGTATTTCAAGAAATTGTGAATAACGTTGCAGAAAAAGTTAATAATTAAGCAAATCAAAAGTCAGAAGTTAAAATTTAAATTATTCAGAAACTGGGTTTGTCGGAGACGGAGATGGCTATGGTAGGGCATTTAATACAAACCCGGTTTCTATGCTTTAGTTATATCCTAGATTTATACTACAAAAAGTAGTATGTAACAGAGAAAAAATTTGAGTAAGTATTTAGACTTAACCGAAAAAATCTTGAACTATACAACAGAATCAACTCTATGTCTAAAATATTTTATTGTTCTTTCTGATACCAATTTTCTATGAAGCTGTGCTTAATATAAATTAACAAGATGTAATAGTGAAGAAAATAATAGAGCGATCGCCAGCCTAAACATTGGCCATTAATAAAGTATTGGTAATAAATTCCCAGCCAGTTATTTGAGATATTACTTTTTGAGTTAATTTATTTAAACTCTTAGTCAGAGCAATTTGTCATTTTTCTATACTGTCAAAATTAATTAACTTAAAATCTTCTTTAATGTATCACCACAATCTCTCTATATAATTAACTTGTGGACTATATGGTAGTTGAAATAATAGAATAATATTCTCAGGAAGATTTAAGTTTAAAGCTTTGTGTAAACGACTTATTTAAACTCTTAGTCAGAGCAATTTGTCATTTTTCTATACTGTCAAAATTAATTAACTTAAAATTTTCTTTAATGTATCACCACAATCTCTCTATATAATTAACTTGTGGACTATATGGTGGTTGAAATAATAGAATAATATTCTCAGGAAGATTTAAGTTTAAAGCTTTGTGTAAACGACTATTCTCTAACTAAATTATGTATATTTTATGAATTCAATTGCTATCCAAATAATTCAAAAAACTTTTCAAAGCCAATACAATTAATGAGAGTAAATTCCCAAAAAAAGCTTTCTCCTTTTAATGGTTATACTAACTATTATAACCATCTATATCAAAATTTTCATTGTTCTTTTCCTATCGATTTTACTCTTTTGAAAGTCACCTTTTATCCAGAAAAAGTTTTAATCTCAAAACGACTTTGATCCTGACACCAATCACGAATTTTTATACTATCTTTCAACATTTATTGATTTTTATCTAACAGAGATTGAATTAGACCTGGTAGTTTTTTTTCCAGTTATTTACAGCATCTTTTTCTTGTTTGATATTAACTGGACGTGGAACTGTGAGTTTGGTTTTTAATTGATAATGAGCTATTTTAGATATAGTTCCATAACTTGCTGGGATATTATAAACACTCAATACCATTTATAAATTTCAGTATAACTATAAAAACCTTCTGGACCTTCTAATTCTCCTTTTAATTAATCTTTAAATATTTCTGGAATTAAAGATTGACGACCATAACTGGTATCAATTGTTAATAGTTTTTCTATTCTACCTTTACAGTAACTTAACTATCTAGAATTTGCTTATGATATTTTTTTTTCAAGGGGATAGGAAAATACTGTGAAGTGCTCTACTTGCTGTGAGGATTATTTTGTATTTTTTTTAGAAGTTTAAAGATAGGATATATTACTACTAGTTGTTATCTTAAATTACTAGCCCCTTTATAAGTCAAAATATTTCAATATACAGGTGAAACTTTCTTGTTACAATATACTAACCATTAATATATTGATATTCTAGTATTGAGCCTTATCCAAAATCAGGACTAATCCTGAAGTAAGGCGGAATAAATTTTCTGTCATTATTTTCAATAAAGGAAACTAGAATAAAAGTCAGCTTAACTCCTTGAAACTCAAAAATATTTATATGTCTTTGCGTTTACTTTTTGATTTTATTAGCAGGATAAAATAATTACTGAATTTTGATATTTTTACAATTTTATGTACTAATACTCATGTATAATAATATTTATAATATTTCTACTTGAGATGAACTCAAATTTTGCTTAATATGGTTTTTATAAAACCCTAATATCTTCACTTTTATTGATTTTTATTTGTAATTACTAACCATTTTTTATCTTAATATTTAAGTCTTTCAAAAGTTCCCGAAATAAGTAAATAATCAACCAAAAGTAGTAGTGTAGTGTGTTTTCTCCGCAAACGCACTACACCTCAAAATTTCTCAATAAGCGTTGTCTTTTAGTTGAATTACTATTAAGTTATCGAAAGTAAATCTATTTCTAGATATAGCTTTCAGCTAGCTTTTCACATCATAAGGATATTAATCTTAACCAAGTCTGGAAATAATGGTGTATTTTTTCTTCAACTTGAGCAAGTAAATATATTTACAGCTATTTTAAATAAGTACTGCTTCACTGGAGAATGGATGTTGCTGAACCAAGGGATGAGTTTTTTGCAGAATTTGCAGAAAAGGTCAATCCTATATTTGACTTCCTCTTTCTCTAAAACTGTAATTAATCTCGTAAATATGCAAAGCCCGAGAATAGGGTTTAAAATTTTTTGAGAAATGGTAGAGTATCTCCAGTGTATAAGGTATAACCAACAATCGGACCTTTAACACAAATAATTTTTCATGCTATGAAACTGAACAAATTGGTAATTTAATTAATACTACCAGAAACCATCACACTGAATACCGACCACAATAACTAACTCCTTGAATGCTTTTATCAAAGGAAGTATTACAAACTACCCATGAGCAACACCAATTATCTGATTAGGATTAGACAAATGTAGAAGAGCCCAAATTTGGAGGTACATCTTGCCAACGCCCTTGACCTACTGCTTGATTTGCTTCTTTAAGACTAATACCTCCAGTATACAAGGCACGACCAACAATCGCACCTTTAACGCCAATGGTTTCTAATGCTAGTAAATTTAATAAATCGTTAATTGAACTAATTCCGCCAGAAGCAATTACTGGAATACTAACCGCAGTAGCTAACTCCCTTAATGCTTCTATATTAGGTCCTTTGAGAGTACCATCCCGGTGAATATCAGTATAGATAATTGCTGCAACTTTCAATTTGGCCATTTGAAGTGCTAGGTCAGTTGCTAACACTTGTGAAGTTTCTAACCAACCTTTAGTGGCAACCTTGCCATCTCTAGCATCAATACCTACAATAATTTGACCAGGAAACTTTTGGCAAAAATCAGAAACTAACTCAGGTTGTTCTATAGCAACAGTACCCAAAATAGCCTGCTGTACTCCAAGAGCAAGTAGACTCGCAACTGTGGAATAGTTCCGTAACCCACCGCCTACTTGTATTGGTATATCTACTGCTTTGATGATTGCTTCAATAGTCTTTTGATTGACAGGTTGACCTACTTTAGCAGCGTCTAAGTCTACTAGGTGTAGCTTAGTTGCCCCTTCATCTGCCCACCTTTTTGCTACATCAACTGGATTATCATTAAAGATTTGGGTTTGCTTATAATCTCCTTGATACAATCTTACACAACGTCCACCTAATATGTCGATCGCTGGAATTATATTCATAGATTCTATGTTTTGTATACAAAACTACTAACTTTGTCAATAGTTGCACCGACTGTTAACATAATACACAATCGAAACTATAAAGAAATTTTTACTCCTGCTCACATCAAAACTTTTGTAGTCCAATTATTGACAGCTCTTAAAATTGAATAAGTATCTTTTGCTCCATAAAAATCAAATAATCAAGGTTTATAGTTATACTTTTGAGATTTTCTTGAGTATAAAAATGGGAATAATTATTAGACTTGTCGCTAAATAAAACTCTGAAAGTGGGACTCGCAAAATTATAGTTTTACTTCATCCACCTATGCTGGCATTCGATAGAAATTATAGAATCCTACAAAAGTTAATATGAAGCGAATAAAAAAACGCATACACTGATTTTTTGGCTGCCTTAAGTGCTGTTGTACCGAGTAAAAGACATAAAGCATTAGGAAAAGAAATAGGAGAGACTTTTTGCATTAAGCGATTGAATAATACCATTTTGATAAAGGTTATCTAGGCCTTTGGGAAAAGCTTTGTTTTTGGGAGAGTGGTTTGTGTAAGGGAGCAATTGTGGCAGCTATATCCCCACCTTAGTGCAAAAAAGCCAGAAAAAGATATAAGCTTTTTGATTTCCCAATGATTAAAATTAAGGATTTTGAGGCTTTTCAGGGATAAAAATTGAAAGAAAAGACATCAGTACAGGACAAAACATTTTAAAACGTTATGAAAATCAGCTATTTTGCTAGGTATATTCAAGAAAATATTACCCAAAAATATTCTGACTTCACCAACGGCTAAATTGCTAAAAATCACTCTTAAAGGTAAATATCAGCTTCCATCAACAATTAAGTCTGTGTGATAAATCCTGATAGAAAACCCCCAATTAAACGAAAGATATTTAAACCATTGTTTACATAGAAATTCTCTATATCCTGTTAGGTATGCTGTTAGGTATGCTACTCACTCCTTACTTAATAGGGCAGCAAATTTCTCCATTACATTTATTCGTTTAGTAGTTTGGGAACTTCCTTTTTTCGGCAAAGTCTCCCAAATTATGGGAATTGCCAAGCCATGCTTAGAAATTCCTAATATGATAATTTTGTATGTTTTCAAGCTACTATTGAGTTCAGTAATTACTCAAAACCCATTTTTATGAGCAGTTCATAATGGTGATCAAAGTCTAGAGGAATTTTCTGGTATCTATGTCAAAGTTAGGGAAAACCTTTGTAAGGGTTTGTAATTAGAACTTACTTGGGCATTAGATGAGAATGCAGTTGCTATTTGTACCTGGTTAATACTTTTGACTTGAAATATAACCTAGATAAATAAAAGAAGAAATTTGACTCTGGCTTCATGCTAATAAAAGTAGTGTTTAAAGTTTTTTGTAGTCAACTCTGGAGGGGTAATAGGCAAGACTAAAAAGCTGACATAAAATGGTTTGTAGCTTTTATAATTCTCTGATAATTGAGCCATTTTTGAGAGTTATTGGCTATCAATTCCTCTGTTTATTCTGCAAACATGAACAAGGAATTTAACCAATATTGACCTCTATTTCCTGTATAAATATAGCTATTTTGTTTATATTTTATTCCTTTTTAAATTGGATAATTTACATAATTTACGACTCTTTTTTGACAATGTATTTTTCAAAAATTAATAATTAATAGGAAGCTAAAGTCATCAATAATATGATAGAAATTAATATTTTACCTTAACTTTAGTTACTTCCAAATTATAGCCTATTGTATTAAGAAATGGGAACATTTATTCAATACCTATTCGTTTTTTATAGGTATTTATTTTCATTTATAAATCCCATAAATTTGTAATTATAAATTATGGCTGTTTTACTATATTTTTTTCGATTTTAAGACAATATTGATTGATATAAAATACTTAGATTGATTGATTTTTTTATTGTAAATATATAGATATATTCAGCTTTATTTATAATAATATTATAGCTATATATAGTTATATTTATATATACAATCTTTTTTTTCTCTAAAATAAAAACATGTCTTTTATTGATTTTTAACTATTTAGCTAGTTCCATAATATAGAATAATCTATTTCATAAAGCTACTTTTTGGCAATCATCAAATCGAGCTAAAACTATCGGGATAAAACTTTAGATAAATATTCTTGCTTTCCTCTAAAATTACTATTACTTTTTTTGTCAATATTAGTAATATAAAATTGACTTACATATATCGCAATTGTTGATATTTATCTATATTTTTTTCTATTTTAAGACAATATTTATTGATATAAAATACTTAGATTTATTGATTTTTTTTTATTGTAAATATATAGATATATTCGGCTTTATTCATAATTATATTATAGCTATATATAGTTATAGTTATATTTATATATACAATCTTTTTTTTCTCTAAAATAAAAACATGTCTTTTATTGATTTTTAACTATTTAGCTAGTTCCATAATATAGAATAATCTATTTCATAAAGCTACTTTTTGGCAATCATCAAATCGAGCTAAAACTATCGGGATAAAACTTTAGATAAATATTCTTGCTTTCCTCTAAAATTACTATTACTTTTTTTGTCAATATTAGTAATATAAATCGGCATACTATTAAGTTTATAAATTAGGCTTATTAATAATAAATTTACCCAATTAAATTGACTTACATATATCGCAATTGTTGGTATTTATCTAGCTTCAAAGTTTGATTAAAAAAAATATTTGAAAATTAGAAAACATAAAGTTTAAAATATTAGTATTTTTAATGATAAAAACCTTTGCATAGAACGAAGACAGCTCTCAAAATTTATATATTTTGGTATTTTATTTGCCAGAGTTTCTCAAGGTATTCATCGAGATTATTGAATGATAGCAATCAAAGCTTTCAACATTAACCAAAATTGAATTTTGATTGACTTTTTAAATGTTTATGGTGGGATAAAGGTAGTTTATTAGTTATTATTAAATAAGCCTTGTTGAGAATATCTAGGCTCATCTTTTTTGATCATTTTTTGGTTAATTCTTGATACTGAAGACTTTTTAACCTTTTTGTCATTCCCCCAGGTAGTAAACTAATCTCCCAAATCTTTAGGTTTCATGGACATTATGCTTTAAGTTATATGAAACCTTTTCCCCCATTAGAAAGTCAAGCTTTTTGTCCTGTACTTAGAGAAAATACTTTCAACTACATCCTCTGTTATTCCCATTTATCCTAACTTCGGATCTTTGTAACAACCTTCTTGCTAATTCCGTGCCGACCTACCTCTTACCATTACCAATAAAACTTATTCAACAAAGCCTAATTAAAATAAGTAAATATTTTTGCACAGACACTTATTTATATAACGAGATTCTATATAAAAAAATTAGAGACGTTGGCAATAGCGTCTCTAAAAATCCTATTCGACCATTTGAGTCACAAATAACTTAATTATTCTGTGGCAGAGATGCTTCTTCTACATATATTTCATCCTTTAAATTCTTATTTTTATCAGAATAACTTTTATTATTAGACTTCTTAGGTAACTGCTTTTTCAACCTTGGTTTAGGAGTTTCGTACATAGGCTCATCTTCCTCCTGAGAATAATCAAGTCCCATCCAAGCAGGACGAGTTTCATCATAAGCTATCTGTAAAGCTGCAGCCGCGATCGCATGGGGATCATATTCTTTACCTAACTGAGAAATTAAGGGCAAGAAAGAAGCCATCCGCTCACCACTCAGAGCACTTCGCACTTTATCCTGTAATTTCTGTAACTGTCGAGCTTCAATTTGAGACCGCTTAGGAATTGAACGAGTGTTCAAACGTTGACGTAAATGACGTTCTATTAACCGCAACTTCCGCTTATCTACAGGATGAATCAAGGAAATTGCTGTTCCTTCCCGACCTGCACGACCTGTACGACCAATGCGATGAACATAACTATCTACACTATCAGGCAAATCGTAATTAATCACATGAGTTAAATGATCTACATCTAAACCACGAGCTGCAATATCAGTTGCCACAACCCAACGTACCTGTTGATTCCGAAAGCGAGTTAACAACCGTTCTCGTTGAGACTGGTTTAAGTTACCGTGATACTCATCAACACTATGACCTGCTGATTGTAATTGATTTGTTAGTTCTGCTGCAGCTTGCCTTGTGCGGACAAATATCAAAGCTGCTTCTGGGTCTTCTAGTTCTAAAATTGGCTGTAGAGCTTTTCCTTTAGACCAACCACGAGGTAATATGTATACAGTTTGAGTGATGCGCTTAGGAGTAGTTTTTTGTTGGGCAACTTTAACTGTTACTGGTGATTGCAAATACTTATTAACTAGTTTCCGGATTGAATAATCCATAGTAGCGGAAAAGAAAGCTGTTTGACGTTCAGCAGGTGCTGCTTCCAGAATTTTTTCCACATCTTGAATAAAACCCATGCTCAACATTTCATCAGCTTCGTCTAAAACCATCATTTTCAAATGATCTAGTTTCAAGCTATTTCGATTCAGCATATCTATAATTCGCCCTGGTGTTCCCACTACAATATGAACACCCTTTTGCAGACGCTGGCTCTGACGTTCAATAGACTGACCACCATAAACCGTTAAAACAAATAACCGCCGTTTAGTAGGACCTTTACTATTAATTCCAGTAAATTGACGAATCGCTTCTGTCACTTGCAGTGCTAACTCACGAGTGGGAGTTAAAATTAATGCTTGAACTGCATTAGTATCTATATCAATTTGCTCCAATATTGGTAACGAAAACGCTGCAGTTTTACCTGTTCCTGTTTGAGCTTGACCCACAATATCCTTTCCCTCTAGCAAAGGGGGTATTGCTTGAGCTTGGATAGGGGTAGGTTCAGTAAAACCAATTGTTTCCAGATGATTTGCACGTTCCTCTGAAATTCCTAAACTTGCAAATGACAAATCCATTCATTCTGCTCCATAAAACTTATACAAAACCTCACAACATGACAATTTGATGTTTACTTCCTGCTTCAAACGAGACTATTGGCAGCACTTTGTCTACAGGCGTTAACGGCTAAGCAAACCGTATGAACTTAATTGATAAAAGCATTCAAGTTTCTTGTTTATCCGGTTGTGACGTTACGTTAATTCAATCTCTGGTTCCTGAGTCACCCAACTTGGAGGCGGATTTACCTTCAACCATAAGCGATCATAAACCCTTGCTAACTATCAACTATTAGACCATAGTTATAGATAATAGATAACATCTTGGTAGGGCAATATGCCTTTGCCGCCAACAATTTCCACTAAACTGATAGCACCAGAGTTAACTATTACCAGTTAAGCGGTGTCTGTGTATTCTCTCAAAGAGACATAATTTTTGGCCCAATGCCCTTTTCCTTTTTCCCTAGTTGGGTAGAGTTAAATACCCATTTGTTGAAATCTTAAGTTGGAACCTCTATTTAAGAATAGTTGCCTGTGATGAATCTTAAAATCGCCCATTGGAAGAATTTAGTTTCAACGAGCACTTCAGATAATCTACAGTTTACTGTTAGTGGCCTTTCTTAAGCTTTATAATCATTTACATAATAACAAATGACTTAACATTAAGTGTATTGTTTAAACATTTTTCTTAGTGTACCTTTTTTGTGATATAGTTTTACATCCAAAAAATACATTATATTAAATCTGGTAATATTAGTTGGTATAAATAGGATGTGCTCAAAAAGTATTTTTAGGGATTAGGGAGTCGGGAGAATCATACATGAGGTAACACTAAAAATTATCCCTTAATCTTTTTACCCAAATTTTTCCAAAATGCTAGTGGCTTTTCGGACTTACAACTAGGCATTTTTCACACTTCCATAAAATTAAAACCTTTCTATATTTAAATGCTTTTAGAGTTAATCACCTAGCCATAAATAAAATATGGAAACCGAGGAAAGTACTAGATGGCCTACTATACTAACATCTGTATCCGATAAACTCCTTTTCTTATAAGATTTCAAAGCAAGTAGATTTAATCTTATCCAATTTTTGGACTCACATGTCTTTATTCGATATTAAATTCAGATAGCTACCAATTTAAGCCTGGACAGCCTAATAAAGGTTTAGGCCCACAGTGATAGAAGCTATTTGCAGAGGGGAACTTGTCCAGTGTTAGGTTGGTAACCGTTAAAATAATTAGGGTTTACTGAAAAACTCAACAGTACAAAGTTATCCTAAAAAAAACCAGTAGTTTTAAAGGCTGAAAGTATTATAGGAATTTGCTTACAGCATTTATATTTGTTTTGAGAAAGTTTCTAACCTTGAAATAGCTGTAAGCCAAAGCTCGCAAAGTTATTCCCATAATTTCCCGCAATAAAAGTGAAAAAGTATTTTTAGGGAGTAGAGAGTCAAGAGAAATATAGAATAGGTAAGAGTAATAATTATCCCTTAATCTTTCTGCGCAAGTATATCCAAAATAATAACTTTATGTGAGCTTTTTGAACTTAAAAGCTGAGGATATTTTCATTCCCAGACGGCTCAAGCTTTTATCTTTAAATCCTTTGATAGTTAATTAGCAAGCCAAGTCTCATTGATAATGAGAAGCAGGAGGGTACAAATAAATAGCCTATATGTATAAAATCTTAAAAGCCTTACCCACCAATTTTTTCATTTTTTATTTCCTAGTAGTGGAATTAAACTAACTTGATGATTTTTGATTACCTCAAAAGTATATACAAAAAAGACTTAATGACTTGGAACCTTCGGAGTCTTTTCACCTTTTAATTTAATAAAATCTACAAACTACCCGTACTACCTTAGTAGGAACTTACCAGAGAAGATTATACCCTAATTAGGATTATTAGCGATCGCTTTACAGAAAAATTTGGTTTAGAGCCTTACTCAATAGGGGACAACTTTATTTTATGGTCACCAAAAGTAGAAAAGCTCATGGGAAATATCTGAGCAACAGGTACAAGAGAACCAACTTTTTTTTTAGTTTGAACTGTATCCTTGTATTCTCTAAAAGTTGATTTAATAATTAATCTATTAAATGTCCCCCCAAATATAATCAATTTAGTTTCAACCCATAATTTTAAAATTTAAAAACCACTAAGAGAATTTGGGAAAAGACTTTTAGAATGAACCAAAACATACAGAAAATTAATATTTCCAGATTAGATATATCAAGGTCTTTAATCTCAGTGGACTCAATGAATAAATAATCCCAGTCAATTAATAAATAATCTAAAGTTTCAGCAAAATCTCTGGGCTCCGCCTTTAGGCCGCAGAGCTTATCAAACAACCATACAAATCGTAAATATCAGCATCTGTAATCATCACTGGAACAATACATCCTAACCTAGCTTCCCCTTTCACATAAATAAGTCCATCAACTTCTGGAGAAAACCGTGGGGATCGACCAATTAACTCTCCTGTTTGAGGATTTTCTTGTTCAATCAATACATCAACTAATTGCCCCACTAATTTTTGATTCTGTTGCCAAGATATGGACTGCTGAACTTCCATAATTTCTTGACGACGAGCGTCCATAACTTCTTGGGGCAACTGATTGGGCAAATTATAAGCAGGAGTTCCCTCTTCTGGAGAAAAAGTAAAGACTCCGACATGATCAAACTCATGACGCTTGACAAATTCCACTAAGTGTGAGTGATGTTCTTCAGTTTCACCAGGAAAACCTACTATAAAACTTGTCCGTAATACAGCATTAGGCATAGCTGTTTTTATTCTTTTAATTATATCATCATTAACCTGACCTTGCCAAGGTCTATTCATAGCCCTGAGAATTTCGGGATGAGAATGTTGTAGAGGTAAATCAAGATAAGGTAAAATATTGGGAGTATCTTGGATGGCAGTTATAACCTTGGGTGTCAAACCAGTGGGATAAGCATAGTGCATTCTAATCCAGGGTATATCAACTTTTCCGAGGGCCTCAAGCAGATCTGCCAATTTAGGTTGACCGTAAATATCAATTCCATAATTAGTTGTTATTTGGGAAATGAGGATGATTTCTTTCACACCCTGGTCCGCTAGTTTTTGAGCTTCGACGACAATAGATTCTATGGTGCGTGATCGTGCTTTCCCCCGGAGATGAGGAATAATACAGAAAGCGCAACGATAATCACATCCTTCGGCGATCCGCACATAAGCAACACCTTCAGATGTTGTGCGGTACCGGGGGGTAGTTTCGTCAGCGATGTAAGTAGGTTCTGCAGTAACTTCTTTGACACGATCCCCTTTTTCTACCCGTTGCATCACATCTACTATTTTATGATAATCACCAGTCCCCACCAGTGCTATTGCTTCTGGCAACTCAGCTAGTAATTCTTCAGGGAAGTGTTGTGCCATACAACCTGCGATGACTATTTTTTTATTAGCTTCAGCTAATTCTACTAAAGTTTTGACAGACTCTTCTCTAGCAGCTTGGATAAAACTACAAGTATTGACAACAACATAATCTGCTAATTCTTCGTTAGCATCTACTTCATAACCTGCCTGTACAAGTAAACCAATGATATGTTCAGTATCAATGCGGTTTTTTTCGCATCCCAGGTGAGTAAATGCAATAGTAGGTTTTGTCGACATTTCCGTTATATATCTCTATTAGCAACAGTTTTTTAATATAGCACATTTATCACATCAAAGTACTGAATTTTATCCTGAAGTAAAGCATTCAATTAAGTTAATTTACTTTGACTAAATTTTCCCAAAACAGTAATTTTAAATTTTGGTAATTGTCTTTTTTTGAAAATTTTATCTATTTCAAGTGTTAATGTATTGGGGAGTAAATTTTATTGCAACTATTTGATAGTTTTGATATCAGATAAGCACCATTATACTTATTATTTACCTACTCTATTTTGACGTGAAATATATAGTATAAGAGGTTTAGTCTCAAATATAGGTGTAATTAATTTTGTATACCTGCTTATTATCTAGGATAACTTCAACAAAATCAAGCCATAGATAGGTAAAATCTTTGATATCAAAAAGGAATAAATTCAAGGATATTAGCAGTTATAAGCATTTTTAGGGATTGAGGTAATTTTTATGTTCTTGAGTGACTTTGGCTGTTTTTTGTTTAGCTATAAAATCTTTAATTACTACTAGTTAATGTCTATATTTTTAATTTTTTTTTACTTCTAATTAACCATGTTTTTTTATATAAAAATTTATTTTTTTTATTAATTATTAGATAAAAATGAATTATTTTTTTTCATTTGTAACGTAAAAAAAGTATTATTTATTAGATAAAAAAATGCTGGGATTAATAAATATAAAATTTAGCTATAGATTGTTTAAGATTGCTTATAAAGATTGTATTTATGGATAAATAAATATAGCTTTTAAAATTTGTAATATTTTAGTTTTAAAACCTAAACTTTAACCACAATTTATAGATATTTTTATCCTGTATATTCATATATCTATAAGCTACATACATTTCATAACCCAAGCTAATTAATAACAATTTTTCAAGCAGTATAAAGAGATAAAATTAATCTCAAAATAGTCTCTAATTTTTTCTAAAGCTTTTGCTTATATAGAATTCTACAAAGACTTACAATAGCATATATATCTGACAATTATCAAAAATATTTAGTCAAAAGACGAAATGACTTCGACAATTTTTGGAGAGGTCAAATGCATAATTTTCTTGAATTGGTATAATAGCGTTTCACTATTTCAGGAGAGCAAAATTCAATGGAATATAAAGAACTTAAAAAAATACATTACGGTTTATATAGCTTCTCATAAAATCTTGCTATAAATGTTATAAACAAGGTCAAGAATCTTCAAGTTTTAACCACTACTAAAATTTGGTTTAATTGGGAGATTCTATCAACCCCAATCATTATATTGTCAGGTTAGTTCAATAAAAACAATAATACTAATCTATTTTGGAGTTATATTTTAGATATGAGTACAGAAAAACAAATAGATGACCAAACAGATGACCAACAAGTTTTAGGCCCTATAATTTTAACACTGTTTATGGGCTTGATGATCATTTGTGCCTGGGCTTTTGCTCGTCCTAACGCTTTTAAACGTCCCGATATTGATGTTCAATTAACTGAAAATATAGATTCGGAAAATGTAAATTCTCAAACAGAAGAAAATCAAGTAACAGAAACCTTAGAAACTGAAACAACTAAAACTACAACCATAGAAACAAAAGACGCCGAAACAACAACAACTGCTAAAATTATATATAAACCCTCAAAGGTAAACATAGAAACAACAACCTCTACAAAAAACCCTGCTACTGATAGGACAGAAACAACAACTTCTGCCCAACAACCTACTGCTAATACGAATAGGATAGAGACAAGAACTTCTAGGGATACCGAACAACCTACCACTGATAAGATAGAAACTACTACTAACACTATAGAATCAACTGCTGCATCACAAGCAAAACCTGAAACAGTCAGCGGTCAAACAGATATAGTGGCAACATCTGACTCACAAGAAAAATATTTAACTGAAGCAAAAACTTTAGGTCAAATTAAATTTGAGATCAATGAAGTTGAATTATCTTCCCCAGCAAAGCAAACTGTAAATAGTCTCATTCCAGAAATTAATAAATACGATCCTAATAGAGTTACCATTAAAGTTGAAGGTCATACATCTAGGGTTGGTGATGCTCAGTTAAATAAAGAAATTTCTCAAGACCGAGCAAATGTCGTAGTCGCATATTTAAAAGAGAAGAATTTACCACATCAGGTTATTAGCGAAGGAATGGGTTATTCTCAACCATTGCCTAATAGTAATCCTGCTAGCGATATAAATCAACGCACAGTAATTATTTTAATACCTGCTAATTAACTTGATCCTTTTCTGATCAAATAAATATTAATTCTTGACTAATAAATAAGGTCTCAAACTTCTGCTATTTCAAGAAGATTAAAAAAAATCAGATTTCAAGCCTGGGGTTTTAATGGTAAGTACTGATAACTGATAATTAATAATTAGAGAAATTAGAGAAATTAGATAACTGAAATAACTCTTATTTTGAAGCTGGCAGATTCCAATTTTTAGGATTTTTGCCAGTTTTTTTATGTTTAAATTTTATATAATTTAAAGCTGAATACTAGTTGCTAAATAGATAGGTATATTAAATTAAATGACTCGCAAAAAACCTTTTTCTCCAGAAGAGTTTAAACTTTTATATTCTCAAGTTCCCAGACTTGTTGTAGAAGTAATTGTGAAAACTGAAATAGGTGTGGCATTAACTCTTAGAAAAGATACTGCTTGGAATAATCTTTGGCATATTCCAGGAGGTACGGTTTTTTATCAAGAATATATTGAGGATGCTATTAAGAGAATTGCTGAAGAAGAGTTGAGTATTACAGTTGTAAAACAAAAGTTATTAGGATATTTAGAATATCCTAGTGAAGTAAAACAAAGGGGTTTTGGTTGGTCGGTAGGGTTAGTATTTTTATGTACTACTAATTCTCTCCTTCCTTCAGAAAATCAAGAAGGAGAAAAAATTCAACTTTTTGATTATATTCCCGAAAATATTGTTGAAGAACACAAAAATATATTAAATCAGCTTTTTTAGTTAAGTTGTACAAACTCCCCATCAAATAAAACAAACTTTTAAAATAGTTAGTAATAGTCAAAGGAGCGGTAATAAGAGCATCTAAATTAGCTAAAGTAAAATTCTAAATTATCAGTAATAGCCTGGTTAATTTTCTTACCTACTTACTCACTCCTATTATCAACTATTGGACTATCTTGGTCAAAATTCAAGGAGTTTCTCGGTTCTTGTAAAGCTCGAACGCAAGAAGAAATAAATCAAGTTATGAAAGAGGCGATCGCTTCACTTTACTGAAGATAATATCTTATGAAAGAAGCGATCGCTTTACTTTACTGACTAGTTGATAAAATATTCAATAAGATAGATCGATATCAAAACAAGTCCTTAACCATTGCTGAATTTAACCATAGTTTTAGAAACCTTCCGGGTTATGCTATTGTGCTTCTAATTTTTCGATTACATTTAGTGGAATTTAACTTAGCTTTCCTCCTAGATTTTTCTTTGGTTGTAGTAAAATATTTAGTCCACCTGTAGGATATTTACCTAACAATTTTTTTACTTTTACTCAATTGGGTTTTAATATTATCCCAATTTCTTTTACTATTTCTACTGTTTGAGTTTTCAACTAGTAAATAGCTTGAATTCTTTCCTTTTCTTGAGCTGTACTCGAACTTTTTCAAATTTTTTTGAGAGTTTCTACTGACCCATTGATCTCAATTTTTATTACTCCTGATATGGGGATACTTTCTATAATAAATAACTTCTAAAAATGTAGCCGAAGTTTATTAAATTGGTATTATATGATTTATCTAGATAATTTTATAACTAAGAATTAAAATGACTCAATATTTAAATCATAACTGTTTAAAAGTTAATGAGCCACAAGCAAATTTATGTACTGTGGTAAAAGATTAGTTTTAATAAAGCGTTATCGTGCTTTAAAAATCATTAGCCAAGGAATTTTTGGCAGGAATTTTAAATGCATAGATGAATCTAAATCTTCAAATAATTTTTGTATAATAAAACAATTTTTTCTTCTTTCAAAAGGAAGCAAAGATTTAGAAATAGGTACTAATCTATTTTTTCAAAAGTATGAATTTTTCTATTATTTTAGTATTGCTTAAATAATCCCTGAAGTTTTAGACTATTTTACTAGTAATATAGCAATCCTATTTAAGTTGTGGCAAAATTCCATACTGAAAAAGTTTTGGAAAATCAAAGATTTGAACGTCTGCAAAAAAAATTAAATTGCCACTTAACTATTTTAAAAGAACTACAAAGATGATAAAATTGCCTAATGAAGTTTTTGGTTTGTAACTAAATATCTTCTACAAAGTTTTTTATGGGGCATTCGGAGCAAATTTTAGACAATTTATCAACCATTTTTCTTCGGGTTTTTCTTAATTAATTAACATCAAATATTCTCGAAAATATTGAGAGTTATAATAACTTGCACCGACCCAAAATATTGCCAATCTTTTTCCCGGTCTTTGCTCTTTTAAATATTAGACATCTCCAAAAATTAACAAAGCCTTTCCTTGACTTGATCTTAGCCTAGTTGCCATATCAAGCATCTTTGGTCCTAAAATACGCAATCATAAATCTTTGAGATATTTTCTCTTACTAATTCAACATTTATTTCCCCCCATTTTCACTTTATTCTCTTAATTTATTATCTTCTTTTTATACTAAAATTAATGCTCCTATTCTTCATCTCACTAATCCACATACTACCATTATTACTTTCTCATAACTTTTCTCTTTTAATCTAAATCTTTCTCTCGCAATTCCAAATATTTTTAGTAATCTAATTACATGTTCTACGAATATTCTTTTTTGGGCTTTTTGTTGATTTTTCTCTTTTATTTCTTCTGGCATTTCTTTTTTTCTTGGTTTCTTTTTTGGTTTGCTTGTTCTTTCTGCTCCTTGATCTGCTTTATCCCCTTGAAAATATTGATTATCCTTAAATTTTTCCCGTTGTTTGTTTAATAAATTTATATCACTTAATGGTCCCCTTTATCCGATAATTACATCCACTATTTCTGTTCCTTTTGGCGTCGTTATTATTTGATTTTTAAAGGTATGATTTTTCTTGTTTCCTGAATAATATTTTTCTGGTTTTTCAGATTATTTTGGTCTTTCTCTACTTTGTTCTGAGCTATCTACTATTAATTCTAATTCCATTAACGCTTCTTTTACCCATTCTAATTCATCTTCTTTTTTTTGACTTGTTCTAATAAACTAGCTGGTAATAAATCTGGTAAAATATTTATCCAGTAATGGAATATATTATTGGCTGTTGATTCACTAACTCCAAAATTTATTCCTAATAATTGAAAACTTGGTATATGATGTAAATAATATAGCGTTAAAAATATTTCGTCTGTTTTAGTTAAAGTCTTTTTTCTGCCTCCACCTGGTTTAATTAATCTTATTTCTTTCTCGGCAATTACCTGGAAATTTTCTGATTCTTTGATAATTGCATTTTCTATTAATTGTGTTAGCTGTTCATAAGTAATCCCTATAATTCTTTTTATTTCTTTCGGATAATTATGAATGTACTCTAAAGTTTTATTCATTGGTATAGCTACCTAAATAAAATTATAAATGAACATGACAATCTTATCTTATTTTCTATTTTGGAGATGTCTATTTAACAAACTCCATAGTATTTTCAGTCTTTCCACTTCTTTAATTATTGCACAATAAATTCCTCAGTTTAATAATAATTTGCTCCATAATAAGTTTGTCTTTCTCTTTCATTTTTAATAGGAATTTCTATTTGTTTATCTTTTATTCCCCAAGAAGAATTTAGGAGATAAACCCATAATAAATGACATTCGTGAACCATAAATATTACAAACTTTTCAGCTTTTATTTATGATTGCCATGTGACCAATAGTTTCTCTATTTCTTTTTTTTTGCTTTCACTAATTCATCATTTTTAGCCGGATTTATATGAGTGAGTTTTTTTCCAAGTTATTCCCGCTTCTTTGAGTAAGTTATAATAACTTTGATTAGACTAAAAAAACACATCATATTGCTTCTTTAAATATTTTTCAAATCTTATAATCTTAAGTAACCTTGTATCCTCATCCACTCAATTATTTGCTCTTTTTCGACAACTTTTAAGTAACCTTGTATTCCAATATAATTGAAGCTTTAAACTTTCTACACAATGAAACATTACTTGATTTTTCCATTCACTAATAAAACTGCTGAGTTACATTTAATAATTCTTTAATTTCACGGTAGGATTTTCCCGAAAAAATCATTTTGACATGCCTTGGCTCTTTTTATTTCTTTTGACTATGCATGTTTTATTTATAAAATCGTCTAGTTCATCTAAAATATTCATTTTTTGTCTAGTGAAGTGGATATATTATTATTATATCTGTTGCGACCTATGCGCGGATTACTATAGTACACAATATATATTTCAATAATTTATTGAAAGAAAAAGTTTAAAAAATGAAATAGAAAAGTCATGTGCTTTTAATCAAAATTAAATATTAGAGTTGTTAATAAATATATTGCCTGTTTTAAAATTTATTTATTACAAATTATTCATAGAGATATTAAGTATAAAAATATTATAAGGAGAAGTAAAAATAATAAATTGTTATTAGTAGATTTTGGTTATACTAAATATCCTACAACGACCGCCATATCAAAAATAGGAACTGCAAAATAAAGTAATTATTCAGACTTTTTATATGAGCAAATACCCTGTTACTCAAGAACAATACCAAATCATTATGGGTAAAAATATTTCATATTTTAAAAGAGAAAACCGCCCTATAGAAAAAGTTAGTTGGAATGATGCTACAGAGTTTTATCAAAAGTTATCTAAGAAAATGGGTGAAAAATACAGTTTACCAAGTGAGAGTCAGTGAGAATATGCTTGCCATGCAAGAAGAACTACACCATTCTATTTTGGAGAAACTATAACATCTGATTGAGTTAACTACTATGGGCATTATACTTATGGCAACAGTTCTAAGGGAGAATTTAGAAGACAAACAACTCCTCGATGTCAATTTCCACCAAATGTTTTTGGTTTATATGATATGCATGGGAATATCTCGGAATTCTGTACTGATGATTTCCATCACAATTACAATGGTGATCCTAATAGATGAAACTTTTTGGATTATTAGTAATAAAAAAGATAATACTAAAATTTATAAAGTAATTTGTGATGGGTCCTGGGACGTTCTTCCTTTGAGGTATCGCTCTGCGAGTCGCAACGTCTATATCTCCGTCGAGGACGACTTCGATATTGGTTTTCGTCTTGTGAGTGTTCCCCCCCAGGACTCTTGAATAGCCCTCTTGCCCTCTTGCTCTTTTGCCCTATTTAGTCTCACCTAAGGCGAGTCGAAAATTTTTCCATAGAGCCGTATTGCTTATGTAGTATATGCTTGTTTTAGAGCAATTAGTGACTGTTAAATTTAGTGCTTTTCTTCATAGTACTTAGTTATTTGTTTTTGAAGTTTAGCAAGTTTATTGCTTTCAAAAGTGATGTTTTTTCCAGACAAAATAATATCAACAGTCTTAGACTTTGACTGAAGCAAAGCATCAACTACTTTGTCTATTTATCCTAGCTGAGGCTAGTAAATATTAGCAGTTTTTGTCTGACCAATAAAGCATCAACTACTTTGTCTATTTATCCTAGCTAAAGCTAGTAAATATTAGCAGTTTTTGTCTGACCAATTCGGTGAATTATGTCTTCTGCTTGTTCAGTGTCTCCAGAAGTCCAAGGCATGTCAAGAACAATTAAATTGCTAAAATTAGTTAAAGTTAGCCCAACACCACCAGCTTTCGTACTTCCTATGAATACCTCATACTTGCTTTTTTGAAAATCTTGAATATCTTGTGTAGGAATTAATATAGAAGAAGCACCTGTTAATTTTCTACAAGAAATATTTGCTTTCCTCAGTTTAGAATAAACGTCATTTATACTAGATAAAAATTCGCAAAAAACGACTACTTTGTGACATTCTGAAACTAAATATTCTACAGCTTCTAAGCACTAATCAACTTTAAGCTCAGAGTTACACTGTCTAAGAATATTAGTTTTAACTAAAGCTTAAGTACCTACCTTGATTTAATTAAAACTTACATTTTTTTGATGTAAACTCCAGATAAAAAAGTATTTAGAAAAATATTTTTTTTCACATAAAAGTTGTAGTAATAACAATTTAATAAACTTCAGCTAAACTTTTAAAATTTATTTGAGGTAGAAAACAACCATTTCAGGAGTAGTAAAAATTGAGATAAATGAATCAGTATAAACTCTCAAAAAAAATGAAAAAGTTATATTATATTTCAAGAAAAGGAAAGACTTTAAATTATTTACTGCTCGAAAAATTAAACATTATAAATAGTAAAAAAAATTGAGATAATTTTAGGATATAATCAAGTAACAGTACAAAAATAGTTAGGTAAACATCCTACAGGTAGACTCAAGTTTTTACTATAACCAGAGAAAAATATAGGAAAGAGACTAAGTTAAATTTCACCAAATGTCATCGAAAAATTAGGACCACAATTATAAATCCCAGAAGGTTTTCAAAGCTGTGGTGAAATCCAGAAGTAGTTAACAACTTATTTTGACATCTATCTATCTTATAGAACAGTTCATCAACTAGTCAGATATAAATTAAAAAGTAAATTAAAAGTTCCACATCCAAATCACATCAAACAAAATAAAGAAGCTCAAGAAAACTTTAAAAAAAACTCTCATCTCAACTAGAAGATAAAATTGCTGTTTCCCTATTAGTTTCAAGACGCAACTTTAATGAGATTAAAAACTATAACAGCTAAAGTCATTAATGCTTGTAGTGTTAAGCCCATTAGCTTATATCAATAGTTATTTAAATATCTATGGATTTATGGTGTAGTAGAACCAAAAATAGGAGATTCCTTCTTTGATAAATTTATTTATCCAGATACCCCTTGCATTGAAAAATTTTTAGAGCTTTTTTATCAAAAATATCCAGCCAGAAATTCTAATTACTTAACTAGATAGCAGGGGAGATTATCTAGGCAATAATTTAGGAAGTAATAATATTATTTTGCTATTCCAAACTCCTTATTTTCCAGAATTTAATCCCATTGAAAGACTGTGGAAAGACGTGAAAAAAATCTGGAAAAATAGATCTTTCAATTCCTGAGATTTCTTACGCATAATTCTAAGAAATAGATTAACTAAATTTAGTCAAAAATATATTGTTTCTTGTACAAGATATAATTTTATTCTTGAAGCATTATCTGTAGTTGGACTTTAAGAAATTAATATTAGAATCTAGTTTTTCCTAATTGAAGAGACAAAGACGTAGGGAAAGAAACAGGTTTAACGCCTAAAAAGCAAAAGATTAAAGAACACTTGAGGTCAAAGAATTTCTCGGTTAGTCAGAAAGAATACTTGTCCTTTAGCTTAACCAGCTCATAAGATAAGTCCCAAAAACTAGGGATAACTAAATGTAATCATGCAGGTTAAATTCCCGCCCTTCGGGATAGGTCCTTGACTTCAGTTGTTCAGAATTCGGTCAGTAACAACTTGGTCTAGAGTTGCTAGGAGGCTAACTGCAACAAGAAATGATATGCTGGAGATGAAATAACCCCAAATAACTCTCAGACCTCAAGCTCTGAGTAGGAAAAGTTTAACATAAGTCTTCTAGGGACAAAGATTACCCAAGCAAGCTTGTCTGAATAAATGTTCAAAATATTTAGACGTGGGGAGGTAAGAAGGTTGGTGGGAAACAGAAACTGTTGGAAAGGCAAATTTAGCGTCCAAGGTGTGAAGTAGAAGCTTTGCCCACTATAAATCAAAAATAAATGTCTTACAGGTCAAAATCCACCGTACTAAAATGTAAAACCCTAGAACTATTGAAACAAAGGTTTTTGAAGGGAGTATAGGACCCATATATTTATAGAAAAAAATCAACTCAAAAGTCGATCTATAAGGGCGAGACAATAGAGGTCCAATTTTTTATAAAATATTTTTTTCATAAAACTGTTGCAATAAATATTTTTTGTGTTATTATATATAGATGTGAATAACAAGGGTCGATGCCCGAGTGGTTAATGGGGGCGGACTGTAAATCCGCTGGCTACGCCTACGCTGGTTCAAATCCAGCTCGGCCCATTCACTAAAAGGATTGAAGAAAAACGCCCGTGTGGCTCAGTGGTAGAGCACACCCTTGGTAAGGGTGAGGTCACGAGTTCAATCCTCGTCACGGGCTTTGATATATATATGTATGAAGTTATTTCAAATTTGTAGTCTTTACTTATTTAATTGATCATCATAAATTTGTGAAGTATCAAAAAGTAATTTTTATTATGAATACTAATTCTGAAAGCTTTGATTACTTTATTCAAAGACCTTTGAAATACCAAAATTTTATTAATAAACTTAGGAAGCAATACTCATAGCATAAGTGTAAATCATAAATAGGATAGCTTCAACTAAAAATAATAAATTAGTCCCGCTCAAGAACCAAGAAAAAAGAAATAAGAAATATTATCTAATAACTGGGTACTTGATTAGCCGATAAAATTTCTAACTTATAAATAATTTGTGTTGCAAGGATTTAAAGCAATATTAATTAGTTGAGTCTATGCTCATTAAAATTGCCATAAATGTCTATTTATAAATCTAACAAAAGAAACTTTATATTGGAAAGGTTAAATTTTTCATTGTAAATACTTTAGCTATAAGGGATATTGCTATTATAATGGCGCCAACAAAATTTTGAGATTAAATTTGTTGAATAGTACAAGAAAAGTTATAAAGAGATTTAGGCAAATATAGTTCAAGTATTGACCTATGTCTTCATTGGTTTTTACTAGACATCAACTAAATATTTGACAAAACTTAATCATTAAGTTATTAAGTTTAATGGTACAGTAAAGACACCTGAAAGTTTAAGGCTAAATAACGATAATAAAGATTAATTAATGCTCGAATCAATCATGTAATTTTAGCTTATTGATTTACAAGATTAATACTGGAAGCTCATAATTCAACAAAATCATCGGTTATATCGTGAAATTCACCGACTGTGTTTCTGCTATAAAAATCTTTATCAATATGCTTATTATTTAATTCTTTAGTATTTTGTTTTTGAGAAAAATTATTATTAATTACAAAAACTGTACAAAACAGTAAACCCTATAAAGCTTCCAGCCAAAACCTCTCTACAAATATTGATAATTTTAGAGAGAAACTCGAAGACTTTTTCACCCAATTTATAAAGCTTATAAATAAAACCTATCAAAGTTGAAAAGCTAGCCTTGTCTATCTAGATATAAAAATAAAATAATAGGGATAAACATCCTAGTTTATACTGTACTTGGTCTTAGTAAACTTTAATTAAAACAAGGAATAATCAACTCTAGTAAAAATGAGATTTATTTGCCAACTAAAGTTGATACTTGAGAATTCAAACAAGTCCGCATCCTTTCTTGGCTTAAGTATAAGGAATAATCAACTATAGTAAAAATGAATGAGATTTATTTGCCAACTAAAGTTGATACTTGAGAATTCAAACAAGCCCGCATCCTTTCTTGGGTTAAATATTATGTGATTAAGGTAATTTATAAAGCTAAAAAAATAATATCTCTTAGAACAAAACCGTGTTGCTAGTATTGATATTGGATTAAAAAATTTAGCTAAATTTTTATGGAGTCTACAGCCGAAACTTATAATATAAGAGGAATTAATCCACTATTGATAAGTTGAAAATAGCTAAAATATATTAATCAAGACACTTAAATATTGTTAAAAATTTCCTACAATCTCTTATATCATAAAATTGATTAAGTAAGAGAATGAAAAACTTTATAATTAAATAAAATTTAAAATCAATGATTATCTCACTCATGGCGTCCCATTTAATTATTGAGAACCTAATGAATAAAATATAGAGGAACTTCGATAATTGGCTATAGTCCAGACTCGAAATAGAATGTTAACCGACTCGTATAATTAAGTAGATACGCATTAAAATTTTTTCCTATGTAAAAAACTGTCAATTTACTCTTAAATTAATTGTCTAGAGGAGCTTGTGGTTACTTGATAAAATTTTATATAGTTAAGCAATTTCTATGCCTACCTACTGAGGTTAATTGATTGGGTTATCTTATCAAGTTAAAATGGTAGAAATTAAAGTAATTATAACTAAGAAATCTTGTACCTCTAAATTCCATTTTATAGAGAAAAAAAAATTCAAGTTGATAAAAAAGGTAAGAAAAATCAAGCTACTTATTTACTATCTTTAGAGTAAAAAGAGGTTTTTACTGTCACACAAGCAAAGAATTAATCAAAGAGTAGTGTGAACGTTTAAGAGAGTATTATGAGAAAATTATTCGCAAACGCCTTTAATTATGGGAATTAGGAGGCAGTAACTAGGCCGGTTTCCCTGACTTAAAACTGTTGTGGTATCGTGGTATTGTAGTTAACACAATCAGGTTAATACCTGCAAAATAAGGATATGTCTTATGTGACTATATTTTTATAAACTATAGCAAAATAAATAAATAAACTATTTGTTGGGGAAGGTGGTATGACGCCTACAAAGTTGTCAGATTCAGAAAAATTAGAAATTATTGAACTGTATCAAACTACACAAGAGAATACTATTACTCTAGCAGACCGCTATGGAGTGAGTAGTTCTACAATTAGAAGGATATTACAAAGTAGCATACCAGAATATGAATATAAAGAGCTAGTTCAACAGAAGCAAAAGCGTCCATCTCGTTCCCCAAGAAATATCGGTCATGATACTGAGGAGAACTTGGATGAATCAGTAGATGGGGGTAATTTAGAGTTAGAAGAATCAGGTTATAGGGCAAATGAAGTAGATGGGATGGTAAAAAGACGACGCCGACGTTCTTCTTCATCTAGTGATGCTGAAACTGAAGAACTAACAGAATTGCCCAAATTGTCTTTGACTTCTGAATATACTGAGAAATCAAACAATGCATTTGAGGGTAGTTATGATTCCCCTACTAAAGAAATACAAGAGATTTTAGCAGTAGATTTACGAGAGAAACCTCAAAATTTAGATGATTTTGAGAATGATGATTTAGAAGATTTTGATGAGGAGTTTGATGATGAAGATAAGGATAAGCTTGAAGGAGAAGTTGAAGTTGAAGAAGTAGTAGACACTTCTTATAATATATCTATTCAGAATTCTAGTTACTCTGAAGTTAAAGTATATAATCTGACTGAGGCAGTTCTGCCAAAAATTTGTTACTTGGTAGTAGATAAATTTACAGAGTTAGTGACTAAACCGTTGATAGCTTTTGGGGAATTAGGACAAATACCTGTGGAAGAGTCTCAGAAAAAAACTTTACCAGTTTTTAACAATCATCGAGTAGCTCATCGATTTTCAGCCCGCAACCAAAGGGTTCTGAAGGTTCCTGATGGTAGAATGTTACAAAAAACTACCGTCTATTTGCAAGCGAAAGGAATTACTCGACTACTAATTGATGGTCAAGTGTACAAGTTATAATGAGAACTAAAGAAGTGTTGAGGAAAAATCAATTAATCGTGAATTCAAAAAATCCTGCTTTGTAGCTAAAGCATTATGTCTGCAGCATATCATTTTGGTGATTACCTGATCAGCTTATCAGTTTTTCCGACTGAAGTTAAAGACTTGATAGCAAGTCTGGGCATAAAAGCAGGCTGGTCCTATCTACCAATACCTTATTTAGAGAAAGGCTGTAACTTGAAAAAAGACCTTCTCACATTTGGTGGATTTGATATGAGACTTGATGTTTTTTTTCAGTACTAAAACTAAGCCAAATTTATAGTTTCTCCTAAAATCAAAAATTTTTTTGATGATCTTTTATTTGTTCAAGATGAAATAAGGATGGCAAGATAATTGAACTAATGATAACTCCTATACTCACGCTAAAGGACAATATTACTCCTATAGGAATCTCGATAGATTGGAAACTGAGAAATTTTAAAGATATTGGCGTAGCATTCTGAACTGAGAGTATTGCAATAGAGCTCACCCAAAGTGCCAGGATTATACTGCTGATAATTGGCGGGATCAACTTTTGCATAAGGTATTTGTTTGATTAATATAAATAATTATAATTTAATCCTACCATGAATAATCAAAACAATTAAACCAATTTTACCTTAAGAATATATAGTTTCCCAATCCTCCAATCCTACTCCCTAATATGTGTATTTACTTAATTGAGTAAGAAACTGCTGTAAATTACATATAAATTTAATTAATCTACACTTTTAAACTGAGAAATGCTAGTTCCTTTAACACGTAAAACATTTGAACAATTAATTCCAATTGTAGCTACAGGCGATCAATATAAATATTATTGGGGTAGGTTATCTGAAGTTTTGAAACGAGCTTTAATTTCTGCTGTTTCAGTTTTGGTAATTGTTTTAATTAATGTGCTTGTTCATGATGATGGTGATCCTTTATTCTTATTGGTTGGTATTACTGCTGGTCTTTATTGGTTCTGGGGACCTGTTTTATTAGCTAGTTTTCAGAATGTTGAATTGAGAAGATACCCATATAGTGGTTTATGGCAAGGAAAGGTTTTCGATGTATATCTTAGTGAAGAAGTAGTCGGTCAAGAAGAAAAAGTTAATAAAAAGGGGGAATTAATAATAGTAGAAAATTTAGAGCAACGAATAAATTTAGAATTGCAGGATAAAACAGGGTTTAAAGTTGAAATACAAGCTCCTCTACGTCGTTATCATCAAGGTATTTCTCGAGGTCAGATAGCTGTAATGTTGGTAATGTCTTATCAACAAGATTTAGAGAAAATTGCTAAATATTCAGATGTTTATCTTCCTACTGTAAATTTATGGGTTAGTAATTATCCATATCTTAGAAAAGATGTGTTTGTTGAGGTAATTAATCAGGTGCGTTCATCTCGCAGAAAAAATAAACAACATCAACAACCTAATTTTAAATTTGAGTAATAAATGCTAAGTAAGCATTCAGCTATTAGCTGTCAGCTTTCAGTTTTTTTTTAGTGAATAAAGCAAGCTTTCCCATTCACTTATACTACATTTAACTAATTATTATAAATCTCTCAATTGCTTTTTCCTCCTTTTAGGATAAATATTGCGCATAGCGAATAAATGATCGCTGAATGCTTATAATGCCCTAAATATTTCTGATAGTTGAGTGCTGAATAAGTAAGTCGGTGTTGAAATTGGTTGCTATGTAACAAAATGTAAATTGACTTCAAATCAACTCTGTAGAGGAACTTGAAGTCAGTCTACAAACCTTAATATAGCTAATTTTTTCATGCCTACCTACTTACTTGCTATTAATTAAGAGTTACTGATTAAATCTAAAAGCATTGACTGATATTGAATTCAGCTTTTTTTTAGCCTTTAAAAATTTCCTGGTTGTCGGTATCTTGAGCTGAAAAAGTTATCATTTTTTTTTGCCGAAAATGGCAGAGGTAAGCCAGGGGAAAATAGATCCGACTACCTCCTCCATAAATTCCCCGTTTCTCTTAATTGTAGGGACTTTAGATGCCAAGTTCCTACCTATTCCTCTACTCCTTAAAAAGACAAAGAAGAGCACATCCTAATTACCTGGACTTTTTTGGCCATAAGCCTGCCAGGCCAAGTCTACTAAACCATTAATAATAGCAACTGCTACCACAGCACTACCCTTACGGCCATCAATTCTAATGTGAGGAATCATCGAATCATATAAACGTGACTTAGCTACATCCACCCCTACAAAACCAGAAGGAGTCCCAATAACTAAAGCCGGTCTAATTTCGTCGGCTTCAATTAAATCAACAATTGCACAGAGAGCAGTTTGAGCCTGACCAATAACAAAGATGCCTTCTGGATAACGTCTAGCTAAAGTTTCAATTCCCCAGGCAGCGGTAGTTTTTTCCTTCTGGGGTCTAGTAATAGCATCCATTGAACAGTAAACAGGGTTAACAAAGGTATTTTGGATAACTGGGGTAATACCCACTTGTAACATTGGCACATCCACTACAATGGTTGTACGGGCTGCTAAAGCAGCAGCTCCAGACTGTAAAGCATGTTCAGAAAAACTAACCAGAGACTTATATTCAAAGTCTGCCGTAGCATATATTACCCGTTTAACTATCTCATACTCTGCGGGAGATAAAGTATGAAGACCGATTTCCTTGTCAATAATTCTTAAGCTTTGGGCGTCTGTAATATGCCATTCCATATCAGATTAATCCCCTATATTATAGTTATAGTTAGAATAGTTAGATAGAGTTTTAATTGGGCTATCGTCAACTATACTTCACTTAAACTAAACTAATATATAAATGCTCAACTGTTGTAGATTTTTACTAATCTCTACCTTGGTTGATAGTAGGTTAGTCCCTAATAATTCATTCTTAGTTGTGGCTAAATAGAGGAAAAAAAATAGCCCCAACCTAGACATAGCAATAATTTCAAGTCTTTTTTTACTTGCTAATGGCTAAAACTTTTACAAAACAAGCTTTTTGGTAATTTTTCAAGTGATAAAGTGACAAGTCTAATACTAAAATCAAAAGCCAACTCATTACCTGCACCAGGAATTATTATTTTAGACAAGATTTATCAAATTTTCTATGAAGTTGCTAGTGGAGATATTTTTGCTAGAAGAAGGAAGAGCGCTAATTAGAAGTCGGAGCTAAAATTTCGCTGCTAAAATTTCGCTGGCTATAATGTATTTGATTTTTTTCTTCCTGCTCCTACCAGATAGATCCCCAACCAGACGGCTAATCTTGTTGCCAGAACTATGTCCACAAGCATTGACAGTTAAGCCAACTATTAGCAGGATAGGGATTTAATTTGAGCGATCAGCTTCTGATTACCTTTAACTTTTAACTTTTATCTAAAAGGACTTACCAAGAGCTACTTTATATCTGATTAATTAACGGTCGTTGACCACTAAATATAGTATATGATTTGATATTTGGGATATTACCCTAAATCAATAACTCCTGTAATAAATTTAGGAGATATTTATAATAGTAAAAGACTAACTCCATTAACTTCAGAATTAGATTATTAACTTCAGAATTAGATTTAATTGAATAACTTAAAGCTAAGGAGGAGTTAAAAATAAATACTATTAGATAGTAGGAATTTGATTTGAGCGATCGCCTTGATAAATTTTAACTTTTATATAAATTTTAGGAGATATCTATAAAAAAATACTACCTCCATTAACTTTTAATTTCTAATTTATCCTGTGACTTTTCCTCCAAATGACCCTTATTTAAGATCCAGTATTTATCTGCTATTGATAAAAGGTCACTAGAATCATGAGTGACAACCAATAAACTCCAATGATTTTTTAGTTTAGCTAATAAATTTACTAGTTGTTTTCGTATTGACCAATCTAATCCAGCAGTTGGTTCATCTAACATTAAAAGATGAGGTTGCCTAATTAATTGTACTGCCAAAGCGAGACGTCTTTGCTGACCCCCACTTAATGCTTGGGGCGAAGTGCTTAATGGCAACTCCTGAAGTCCTACTTCTTCTAAAGCGGAAGATATTTGTTCTAATCGTAATTCTGGATGACCTAATCGTAATTCTTCTAAAATAGTACTGCCACAAAAATGTCTTTCTGGGAATTGAAATACTAAACCACCTAGTTGTTGTAAATTTTCGGAGGTTAATTTTTGCTCTCGCCAGTATATTTCTCCTTGGGAGCATTTAGCTAGGCCGGCTAATATTTCTAATAATGTAGTTTTGCCCGAACCACTACGACCGATAATTAAACCCATTTCTTTGGGTGCTAGTTCCATATTAATGTTTTCGAGGATAGGGATAAGGCTAGCTGCTGGATGATAATATAGGTTTTTTAGATGTAGCATTTATAAGTCAAAGGGTCTTTTAGTTTGAAGATATGTGGAAGTTACTGCTCGACGAACTCAAATGAATTATGCTCATCGAACTGGAAATATTTAGTCGATGAGAATTTGTCTCAAGCTCAGAAGATTAAAGTTGTTTAAGATAACTTCAATACTCATGTGAAGGTATCTCTCTACAAAGCATTTATCCCATCTGAAACCTGTAGGATTTTAAACTTGTTGAAATTTTATTATACTCCCAAACATGGCAGTTGGTTGAAGATGAAAGAAATAGAGTTAAGTGCATATTACCGATAATGCTTAGGGGGAAGAATTTATTCTCCAGAAGTTTTCAAAGAGGAAGTGACAGCTTGGGAAAATTGAAGAAATGAAAGGGCTTCGGTGGTAGATTGGTAATTTATCTCCAAGGAGGCTCAGGTTAAATTGAAGCAGTTATATCTGTCAATTACTTTTGACAGACCAATAGCCTAGCTGAAGTAATAACAATTTGTTCAATTGAAAATCATAGTTAGTATTAAATAGGACTTATGCTAAAAACATTATTTAGCTGGTGTAAAAATTTTCCAGTATTGAAGAAAATATCAGTTTTTTATAGTGTAACTTTAGTTGGTTTCAACTTTTGGGTAACTCCAGCTATAGGAGATCCATTTCGTAAAATAAATCCTATTGAAATAGGAGAAAAAACCGAAGCAGCTTTTGAAGCTATGTTTGAAGAAGGAAATTATAAAGAAGCAAGAGACTATCTTAAAATAGCTGAATGTGAAGAGATAGGTGAGCCTCTTATTTATGCTATGATTTCTTCCTTGCATTACTTAGATAAAAATTGGGATTCACTAAAATTATATGCTCAAAAAACTACTGAGGTAGCAGAAAATTTAATTGCAATTGATCCAGTTCGTGGTAATATTTATGCTGCAACAGGTTACTTTCTAGAAGGTGCTTATATTATATCTACTGAAGGTACATTAAAGGGAGCCCCAAAAGCTTTAGAAAAACTTAGAAAAGTTTTGAGTCATTTTGAGTCAGCAGAAAGAATAAATTCATCGGACCCAGAGTTAAATTTGCTCAAGGGATATATGGATTTAATGTTAGCAGTAAATTTGCCATTTTCTGACATTAGTAAAGCAATAGAAATATTAGAAAATAAAGCTTATCCTCATCATTTAGCTTATCGGGGATTGGCAGTAGCTCATCGAGATTTAGATGATTTCAAAAAAGCTCTACAATATGTAGATAAAGCTTTGTCAGAAGTTCCAGAAAATCCAGAGGTACATTACCTAAAAGCACAAATTTTAGTTGCTCAGGCTCGGGAGAAAGATAACAATTTATCTCTTAGAAAAAAAGCTAAAAAAAACTTTGATAAAGCTTTGGCAAAGTCAGAACAAATGCCGAGACGTTTGGTAGCACAAATATTTTTTGAACAATGTAAAAATATTAATAATATAGATGATAGAAAACGAAGTTGTGACTCAATGCGAGATATAATTAGAGATGGTTCAGGTACATGGGGGCCTCAAGAGTTACCAGCTCTTCGCTAATTCTAAATTTAATTAAAATTAATTTATCATAAATTTTTATACTGGTGAGCTAGACATCTCCAGTTTTTAGGAAACAGAAAATAGAGAATAGGAGAAACAAAATAATAAAAATAAATTTATACTCAAAAAATGAGTAAGTTTATATCTTAACTCAATAGTTTGTAGCTAGAAAGTTTGATTTATATTGGTCAGGTTTCTGTTTTTTTATACGTCTATCTATGGAAGTATAAACAAATTTTGGCTAATTACTTTGTAAGTTTAATACAGGAGTTATAGTAAATTGTCTGAAAAACTTTAGAGTTTAATTGCAGACTTAAAAAACTATTTAAAAATCTAGTTTTCTCTATTTCATAAATCACTGAATTATCTGTAAAATTTATAGAAAATTTTATATAAGTTAAGTACAATATTATCAGAAAAAATGTCGGTAGGATAGAGTTGTCTCTATTAATTAGGAAATTTATTTGTTAAATATTTATGGAAGTACAATTTCGGGAATTTAATCCTTTTGATGTGTGGATTTGGTTAGAGTTTAGTACTGTTCCTTCTATGGCAGAAAAACATTACATAGAAGAACTATTTGATTCATGGTTTTTATTAGGTAAATTGGGTGGTTTTAATGCTGAAAATTTACAAGTTCAAGAGGTAGGAATAGAGATTAGTTATATGGAATATAGTTATAATGTTGCTAGTCAAAGTATGATGGCTGTTATGCACAATATGGGAGATGTAGAATATGAAGGATTATGGGGTCGTTGTTGGTTTGACTTGGGAACTAGCGATGCTTTAGCAATTGATATTTTGGTGAATAGTTTTCAACAGTTAAGTAAAGAGTTGGTCAAGATAGAAAAACTGATTATTGGTGGTCAAAATGAAGATTGGCTAGTACCAGAAAATAATTATGAAAAGGGCTGGTTTGATGAAAATTAATTGTATTGTCTCTTTTATTTATATGATAAAATTATGAGTAAAAAGAATAAAATTAGGGTGCTAGCTTTGGGGTTAATTAGGGATGGTGATCGCTTGTTTATTTCTCAAGGTTATGATTCTATAAAACAGGAAACTTTTTATCGGGTTATGGGTGGAGGTGTTGATTTTGGAGAATATAGTCGCGATGCTTTACAAAGAGAGTTTAAAGAAGAGATTGAAGCTGAGTTGACTAATATTAAATATTTGGGTTGTATGGAAAATATTTTTATGTTTGATGGAGAGGAAAGACATGAATTAATTCAATTATATAAGTGTGATTTTGCTGACTTTAAGTTTTATCAAATAGAGGAGTTAACTTTTTGGGAAAAGGAACGAAAAAAAAAGGCGCTCTGGGTTTCAATAGATAGATTTAAATCGAGAGAGTTGAAAATAGTTCCAGAAAATTTTTTAGAATACTGCGATTAGAATATGAATCAAAATTTACAAGATAAAAACACTTTTCAACAGAATAATAAATCTCAAAATTATAGCGAATTAAGTCAAGTAACAAACTATTACTCAGAGTTAAGTAAATATGAACAAGATGATGTTGATACTATTAATAAGTTAGCGGAGACTTATTATAATAAAAGAAATTTTACATCAGCGATCGCTCTTTGTCACAAAGCATTAAAAAAACAAGCAAATTTTGCTCCAGTCTACAAAACTTTGGGAAATATTCTACAAGCACAAAATAAAATAGATGCTGCTATTCGTGCTTATTCATTAGCCATAAAAATTAATCCAAATTTTATTGAAGCTATTGTCAATTTAGCCAGTATGTTTTATAAGAAAGGGCAAATTGATGCAGCAATGATTAATTATAGAAAAGCAATTAAAATAAAACCTGATTTCGGGGTAGCTTATTGGAATTTAGGGAAGGTTTTAGAGCAAGAGGGCAGATTTTATGAGGCATTTTTTTTTCAAGAAAAAGCTTTAAAACTCCAGCCAAGTTTAGTTGATAATACTCAAAATAATCATCAAGATAGTCATTTTCAAAAGTGGAATAATTTAGAAGGTAAAATAGGTGGTGGTACATTTTAATGGAAGTCTATTATAATTATTTTGCTCAAGAACAAAGGAAGTATCCTTTGCGGTAGTGTTGTTCATCAATATCTAGCATTTTGCGAGTAGGAGAGCCGAATAGGTTTTCTTAGAAATTTGAAGGACTCATAATTGAATTACTCTTACTCTTTTTCTTTCTTCCTTAGTTTTATGAAATCAGAAGAACAACAGCATCCTCAATATCATAAAGATAGAGAAATAGTTAATACCCTATTAGCAGAAGAAAATACTTCTTATAACTTAGCAGAATTAGCAAGATTAAAAATTCGTTATCAAGGTTTTCCTGGAGCAAAAGATATTCAGAAAGATCTAGAGGAAGTATTAGCAAAGTGGAAAATAACTGAAGAAAAACTTTATGAAAAAACTCGTGATATTCATCGGAAAGGTAAGGCATATAAACAGAAAAATACTGACAAAGAAGATTGGCTTTAGGTCAGCTATCAGCTATCAGCTATCAGCTTAAAATAGATTTTTTTGATTTTTAAAAATTTAAAATTATCAAAATTTTACTCTATCTTACTAGATAGTATTTTTAGTATTTTAAGACTGAAAAAAACTATAAATTCTGACTGAATTTTGGTTTTAGTCTTTTTTTTCTTAATTCCCAAAAATTCTAATAACTATAGCAATATACAAATAGAGTAGAAACATTTATATAGCATTTTTCAAGGAACAGTCAGTACAGTTTTTTTATTCTTTTTTCTACCCTATTTTCCTTATTTTACTTGCTTACTATTCTTTAAGGGATGTTGCATACAGCTTCCCTACTAAAACAAATAAATTTTGTACCTTAACAGTGTGGAAACTGCTATATAGTAAAGTGTGCTTGTATATTTACAATTTTTGTTATAAAGACTTACTTTAGAGGGTTTAAACTGTCTTTAGAGAATTTGAACCAATATGCCAGATATCACTGCTATAAATACTCATACTTATAGCAGCGACTTCTAACTTCTGACTTACGTGTCGCTCTATATTTTTGATTTGAGCAGACCTGAAGATTTATTTTTGTAGATACCTTCCTGAAGATTTATTTTTATAGATACCTTCTTATCAATTCTATTTTTTTCTATAAATATGAAACTTTTGGCTATTATGTATAGTTTCAAAAATGAATCTAGCTTGTTCCATAGTTTCTTCTTTTTTCCATTGTTTAATGTAATTCAATTTCAGTTTTTGTTGAGCTAATATTTCCCAATTTTTTTTGCGCTAATATTTCTCAATTTTTATTGAAAAAATAATTTTTATCAATGGATTTAATGTCGTCATTTTTCCCAATTTTTTATATCTTCTGAGAGTAAAGAATTCTTGTAGCTAGATTTTGTTGATAATTTTTATGTTCTTCTTGAATACTTAATAGTAATAAACCGTTTTTATACAGGTGTTTAGCAATATTAATAATCTCTTAATCTCCTCATCAATATCCTTTGTATGACTTCCTAAGTCTATCTGATCGTCTTGTTTGTTTATTTACCAAACCCCTCCATTATAAATAGCAATATCAAAAGTTTCTTGGAGATCCATATCATAGACATCTGCTTCTACTAATTTTCCCTATTTTCCTAATCTCTTTTTATCAATGTCAAGCATTGATGAGGTAGTATTTACTCCCATAAATTCAACCTTGGGAGTAAGTAATCTTAATTTTTCTGTTAATAGCCCTATTCCTTTCTTACACCTAATTAAACTATTTTTTTCGAGGCACCTTTCATCCAAGGATAGACTTCTTTGGGAAGTTTTTAATAACCATAATAGCTTTGTATAATCAAAAGAAATAATCAGTAATACCAGTACATTATACTCATAGTTAATTTTCTACTACAATTAGTATGTTAGTTAACCATACCAGAATAATATAATTGCAAAAAAAACATCAGTTTCCAATAAACTTTTGATAGTCTGAAAGTAACCATTGAGGTAACTTAGTTGCATCCTCAATTCGTAATTGTTCTGGACGACAATATAAAATTGCGGCTAGTAAATAATTTATAGCTTTCGGCGCTTCTATTCCTTGAGAAAGTTGGGTAGCTAACTGTTGTAAAAATTCCTGTTCACTTTCTATTAAAGATTGATTTTGAATCTCACTATTAAGTAATGCTTGATAAGCTTTACCCATCTCACCTAAGTAAAAATTTTCTAGCTTTTGTGGTTCTAAATTTATCCAAAAATCAGCCATTTGTTTACGAAGTTGACGCAACTCTTTAACAACAGACTCATCAGAAGGATCTATATAATAAAGATTCACATTACCTAATAATTGATTTAGAAACTTAGAGATGACAAAATCTAAATTATCTGCCTTATTTTCTGTTAAAAATATATTCTTTTCAGTTTGAACTTCAGCAATTTTTATGGGTTTGCTTACTAAATCTCTACTAATAGAATCTTCTGAAAAATGAGGTAACTTAGTTTGAAAATCTTTTTCCAATTTCTGTACAACTTCTCTACTTTCAAATACCTGTTGATAATCATTAATCAACCATTCTGGCAAACGATTTTTAGCATCTCTGACTAACATTTTACCTGGTAAAAAATATAGCATTCCTCCTAAAAGTGCATTAATTGATTTAGAATTAGTTAAACCCATACTTATATCAGTTAATTCTTTGATAAATTTCTCTTCTTTTTCTGTTTGAGGTTCGTTTTGAATTCCACTTGATAATAAACTTAGATATGCTTGTCGAACTTTACCTTGATAAATAATCTCTAATTTTTGGGGATTTGTATCTAACCAAAAATTAGCTATTTGTTTACGAATTTGACGTAATTCTTCGATTAAAGATTGGTCATTTGGGTCAATTTTGTAGAGGTTGACACAACCAACTAAACGATTAATAAATTCAGAAGTTAGAGAATTATTATCTTGAGATTCTATAGTTTTTGGTGCATGAATATTTTGCCATTTTTGGAATAATTCTTGGAACAATTTACCTATCTCTGCAGAATAACTACGACTGTCTAAAAATGCCGGGTTTTGCTGCATTTTTTCCTTAATTTCTTGCCGTTTTTGTTGTCGCCACTCGGAATTAGTTGCCAATTTTACTGCCAAATTAATATAACTCTCTTCTCCATCAGCAATAAGATCCTCTATATTAATTTCCCGCAACAAAGCGGGCCCTTGCCTAAACCTTAAGGCATTTCCTTCCACAACAACTGGTGGTAGTCCTAGCATTAAGGGATCTAGTAGAGAAGTTGCCCCACCGTAAGGGAAAGAGTCTAAATAAATATCTGCTAACTCTAAGCATTTTTTAATATCTGATTTGCTCGGTAGTGGTTTAATGACAACCAAGCGCTTACTATGAATACCATGTCGTTCTAAAGTACCTCGCATCTGTTGGATAAAAGATCCAACTGGATAAGAATTTGTCCAATTGGGGTTAAAAGGATACAAAACTAAAATCGAATTGGGCACGGCACGGAGAATTTTGGCCCAAGTCTCCCGTATCTCGGGTATAATTTTGTAGAAATTGGCACCTGAAATAAAAATGGTAGTTTCGTTTGTTGCCCCCCAACTGGAGCGGAGGGGTTGCACTACTGGAAGAGTTTCGGCGATGGGATCTTGGAAACATAGTCCGGAACCTTCTAGGTTGACCAATTTTTCTGTATAGTGTTCCTTGGTCATTTCTGTTGGGGCGGTTAATTTGCCAGAAATGTAATAGTCTATAGATGCCATCCCGGTAGTAGTGGGAGAATTAATGGATGTTACTTGAACTCTTGCTAATCGGTGAGTTGCTAGTAAGGTAGAATTTTTGATAGTAGCAGTAATATTAGAACCGAAGAACAAAATATCGAGATTGTCATCACGAATGGTTTGTACTTGATTTTTTAGTTCATTTGGTAGTTGCAGGAATTTATCAGCACGACTTTGGCAATATTGTTCTAAGGGGTGTCCGTTAGATTTTATTGCATAAAGAAATATCTCAAATTTACTCCGATCTAAATGTTCAAATACTGGGAGTAAAGAGTATGTTTCTGTTTGAGGAGTATAGTGATCTTTGATAATTCCTAAGCGAATTTTTGAGCGGTTAAATTGATAAGGAGGCATAGTATAATTTAGCTCTAACCCAAGTTTTTTTAGAGCAAATTCAATAATTTCTGCCCGTTTGATGTAGAGATTTTTTAAATTTGGCCGAGTCGTAAAATATAGAGGTATCCAATTAGCATTTTCGACAAAAATCCTAGCGATCGCTTGCCATAATTCCGACTCTGAATTAATCGATATGTTATTATGAACATAACTCAACCATCCAGTCATAAAATGATAGTAATTATCTGTTTCTCCTATTTCCTGGAAAACCTGAGGAGAAGCAAACATAAAATTTAAATAGTCTATAGCAAACCATTTAGGAATTGGAGCTTTCTCATATTTAACTTCCAGTTGATCTGCTCTTTGATAAAGCATACCTGCCAAAAGATACTTAATGTCTAAAGGTTCCTTAAATCCTTTAACAATATTAGCTTTTATTTGAGTGACAATTTTTTTCTCAGTTTCGGTTAAGCTTTCATCTGTAATACTGCTTGTTAATAAGGCTTTATGTATTTGACAAAAATCTCCTAAATAAGCAATTTTTAGATTTTCTAAGGTATCTATACTTAACCAAAAATATGCAATTTTTTTTCTTATTTCCTGCAACTTAACTAAAGCAGATTTATCCAACTGGTTTTGTTTGTAAAGCTCAATCTCTTTGTTGATTTCTGCCAGAGAAGGTAATAAATTAGTTTCAACTTTATGTGGGGTTTTTTTTGATTCTATTAACTGAGGTTCTAAAGATAGTAGATGCTGACTTGTTGCTTGAATTAAAGAAGTTTCAGCCTCCGTTTCTGCATTAATCAAAATAGAAACCAATAAATTAATTACCGAGGAAGAATTACTGCATTTAAGACCTTCGCGCATTTGAGCGATCGCTCCATTATTATTACCTATTTTCAACATCGAAGCAGCCATTTTCATTGCTTCAATTCCATAATGTTCCCTAGCTTGATTTGATAATTCAGCAGCCATATTTCTTGGTAAATAAGTTTGAGTAATTTCTATAGCTTTCCTCGCATTTTCTATATTACCTCCAGACTGCATTAAGCGGGAAGTTTCCGAAGAAGAATGTAAACGGAAACAGGCCAAAATTTCTGGTTCAAACCAAATAGGATAAAAAGCAGCTATTCGCTTCCAAATTTCCCAGTCAGCAGCCGAAGCAGCTTGGGAACAAAAACCACCCAAATGTTCATAAACCTCACGTTTAACAACCATTCCCACAACCTGAATACGTTGCTCAACGGTAATCTTTTCTATAAACTTTTCTATAACACCAGGAGTGTCTCTTTCCAATACAGATAAATACTTTTTATGGTCATTTTCATCTATATAATAGTGACGACAAAATGCTGCTCCTAGTGTTGTATTTTTTTCTATTCCACGACGCAATTTTTCATAAAAACCAGGCAAGACAAAATCATCATCATGGAGTAGATGAACCCAATATCCTTTTGCTCGTTGTAGACAAATATTAAAAATAGGAGCTTGACCAATATCTTGTGGGAAATGCCGATAACAATTAATTCTTTCACCCCCTACTTTTCGGACAATAGCTTCTATTTCAGCTTGAATTTTATAATCAGGACAATCATTAACTACTTCAATCTGCATTTCCTCTGGAGGAGGAGCTTGTTGCAATACACTTTTTAGAGTTTGTTCTAAATATTTTACCTTTTTATAAGTAGGAATCATCACAGACCAAAATGGTCTATCTTTATTGTATGATAATCGATTAATTTCTGGATACTCAATACCCATTTGGTTATTTTTTAGGGTAACTATTTGAGGTATTTTTTCTACACCTACTTCTACTTGTTGTTCACGCCTTGCCGTTGCCCAAATCCAAGGTTTAGCAGATTTTAAAGAAACTAAATTAAACCCTGCTGCAATTAATAAATCTTTTAATTGTTCTTCAGTATAAGCATTGCCAGAAAAATAATATTGTTGATCTTTTGCTCCTTCTTCATCAAATTTTCCTAAACTTTCAGCACTATAATCATGTACTTGAATTCTAAAATATCCCCCCATTTTTAAGACCCGAAATATTTCACGAAAATAATTTTTGACAATAGAAATAGAACGGATGTGCTGAAAAACTATTGTCGAAAAAACAAAGTCATAATTTTCATCAGGCAACTGTTGTAAATCATAGCCATTATTAACATATACTTCTCCATTTTGTTTCCCATCGGCTAAATATTGCCGTGCAAACTGAATCATATTTTCAGAAATATCTACACCATCTACCCGCGCAAATTTTGCTCGTAAATACTTAATAAGACGACCAACACCACAGCCAATTTCTAATACTTTCCACTCTGGTTTAGTAGGGATACCTTCCATAATTTGTGGCACCCAATTTTCTATTGACTTTTCCCAAGCTTGCTTTTTTTCTTCTGGGGAAAGCGTATCCATTCCGTTATAAGCTAACACCCGCCCAAACATAGCTTCATCTAGAGAATTTACATTCCAAAAATGGCGCTGCATTTCTAACTGTCCATGATTTATTTTAAATTGAATTTCCCCTAAATTTTTCCTGTCTTCCATAGTAGATAATCTCTTTGCTTTAATCTGATTAAAAGTCTGAATAAATACGTCACTCATAATCTTAGCCATTTGAGACCAAGAAAACTTTTGAGCTTGTGCTAAACCAGCAGTAATTAATTTTTGCTGAACTTCAGATTTTTGCACTTCACCCAAAGCATTTACTAAGCTATTAATATCATTATCATTTATATATAAAGCTGCTGTTCCTGCCACTTCTGGAATTGAAGAATTTTTACAAGTAATAACAGGACAACCACAAGCCATTGCTTCTAAAATAGGCAGTCCAAAACCTTCATATTTTGAGGGATAAACTAAAGCGATCGCTGCCGAGTAAGCTGATTTTAATTCTTGGTCACTTAGTTGTAATAAATGGATTTTACTACCTGAGATATATTTACTTAATTCTGGCTCTAGTTTTCTATTTCCTCCTATACAAACAATATCAAATTCTGTGGATTTCTTTAATTTAGAAAAAGCTTGAAAGAATAAAATAGTATTTTTATAACCTAACCAACCTATTCTCTCACCCACTATTAAAAAGTATGGCTTATTAATGTGATATTTTGACTTAAAACTAGCAACTTCTTGAGGAGTTGTTCTGGAAAATTTAGCTTCAATTCCACAGGGAGCTACCCTGATATAATTTGCAGGTATTTGAGGAAAATATTTTATCAAATCCCGAGCTGTATTTTCTGAAATTGCAACATAAGAAATTGCCTGTCGAATACTACGATGTTTTTCTTGCCATGAAGGGTTATTAAGATTTTTGGCTAAAACTTCTGGAATCATATCATAAGCCATAAATACAGATGGCGTTAAGATAGGTGTTGTGTAATAAGTAGAAATGAAAATATCAGCATTTTCTTCATCACATATTGTCTGCAACATTTGACGATCTGCATCTATTTTTCCGTAGTTATATCCAGGCACAGACCGATAGTTGATACCCGGAATTTTTGGTGCTGTTTTTGCTCTATCAAGCACTAATATATTTTTAGCAAAACTATCTTTTGACCATACTTCTAATAAAGATTTCCAAACACGGGCAATACCTGTATTATTGATTTGGAAAAATACACCATCTATAAGAAGTTTTAAATCCAATTGCTGCTGATTTTTTTTCTTTTTTTCTGTAACTTTTTCATGGTCTAGTTGAGTTAAAGTTTTTTTCCTGTTCTCAGGTTTATATCTAGCCACCTTAAAGATGTTTTGAAACTCGCTATGTGATAAACTTTTCTCTGTTAACAGGTGTAAAGATTCTCCATCTGAATATAAGTTAAGTTTAAACTTTTGACCAATTACAGATAATGCTTTTGTGGTGTATATAGAAATATGTTGACCTTCTTCCAGAGCATAATACCACCAATCATTAGGATGAGGATTATTAGGTGGTAGTAGCTTTGTACTAAATAAAATATTTCTAGTGTGTTGCAGTATATTCTCAATTTCTGCCAGAGGATTTATGAAATGTTCAAATACTTCAAAAGCTGTAATTATTTCATATTTCTGCTGCTTATTTATTTCTCCTTCCCATCCTTGATAAAAAATATTTTGGCAATACTTATCATATCCATAAAAATCTAACCCTAAGTCACGCATCATGCGGACAAATAAACCATATCCACAACCATAATCTAGGAATTTACTATTAGTATTAAATAAATTAAGAATTAAGTTTTCTGTAATCAGAGAAAAGTTTTGATTTCTAGATACCAGACCTACATCACTACTAGCAATTGCTTCTTTATAAGCTTCAGCTAACCAATAAGGATTTTCCGTTTGTACAAACCCACAATTAGAACATTGAAAATATTCAACATTATATTTATTTAAAACCTTAGCGTCATCAAATTTACAAGATATTGAACCACAAACTTTGCAATGAACATTTTGGAGCTGTAAACTACCACTAAACATTGTTTTTTCTGTAAATTCGTCAGCTTCAATATTTCGGATAATAGAGGGAGGATGATTCAGAGGAAAAATCATTTCTTCTGTAGACATATTGGCAAATTTATTGATACTTAAAGTGTGGGTAGCTTCCTCACCAAAACCAATATTAGAAACTAAATTAACCTTGGGTAAAATAATTAAACTATGATGATTCCAAGAGGCAAATATCCAAGCATAAGCCCAAGAATTAAACCCTTGATAATTATTCTGAAAAATCTTTGACCAATACTGAACTGCGTGACTATTTTGCAGAATATTTTCTAACCACTTACTATCTCTAAGTTTCGGCCATAGCTGCATCTGATTATCATAATTTTTCCACGCTCTTCGCCAAGTTGCCCAACCCCAACAATGAGGATAACGAGAGAAATAATAACTATATTCTATTGAATTATTACCAAACTGAAAATTATCCCCAGATATAGCCATTACTTTATTATTATCTTGATATATATCTAATAACTCCTGACAAAATCGAAAAAAGGTTAGATGAGGTACACAGTCATCCTCCAAAATAATCGCTGATTCTACTAAACTAAAAGCCCAATTTAATCCACTATAAATACGCTCTCTGCAACCTAAATTAACCTCAGCATAATTAGTTAAAACTTCACATTTCCAATCAACAAGATCAACTATCTTTCTTGCTGCTATACATTTCTCAACTTCTCCTGGTTTATCGGGGCGAGGAGCATCAGCTATTACAAGTAATTGAGGGGGCTTTACTTGACGAATTCTCTGAAATACTTTTTCTGTTGTATCTGGTCGATTAAATATAATTATAACTACAGGAGTTGTTAATTGAAATTGAGTCATTTTTAGCTTTCTTTCACCCTCAAATCTTATATATCACCCGGTTATATTATACGGTATATATTTATAATTCTATAATTACTTCAATATTTAATCTCCCCAGGTCCCTACTTCCCCATCTCCTCCAACTATATAATAAGTATTTAACGGGATTTGATATTAGTAGCTTTATATAAGATATCTTGATAAGACCGTTCCGGTAGAGTCTGATTTATAGAATCAGATAGTACTGCAATAGGTTCATATAATGGTTTTAAAAAAGAGTCAATTGTTTTTCTATCTCTTAAACGTACTTCTATTAACATAAATTTGGGTTGGTATTTATCAAAGTCAATACCTTGCAACACACCTAATTCAAAACCTTCAACATCTAACGAAAACAAATCTATATTTTCAACTCCATACTTGTCAATAATTGCAGTTAATGTCGTTGCTGGTACATTTATTTCATAACTATGATTAATGTTTTGGACTTGGCAACCCGCCTTTAAGTGAACCTTTTTTTCCTCCTCCGACTTCATAGCTCCATCAACAAAAGACATCAGATTACAATAGTACAATTTTATATAATCTTGACCATAATCAAAAGGAACTAAAGCATAATTTTCTACTACTGATTTAGAGCGATTAACTCTACATTTTTCCGCTAACTCTGGTATTGCTTCTATCAGGATACCTTGCCAGTTTTTATATTTTTCAAAATATAAAGTGTTACTTTGACTTATCCCATCATTCGCTCCAGCTTCAATAAAAAATCCATTTTCCCAAGTTAAGTAAGGGGCAAGTTTAAGATCTAGCTGATTCAAAGCAAATGATTTTACAGTTAGATCTCGTTCAGTTTCTAATGCTTTTTGCCGATAAATATTCGCCTCAGATAATCTGCCCTGTTGTTGTAAAATCTGACTAATACCCCAATATATATCTGCCGATTTTGGTTCAAGTGTAATAACTTTCTGATAATAAGCGATCGCCTCTTGTAGCTGAGACTTTTGGTAATAAATTTTGCCTAGCTTTGCATAAACTACTGCCAAATCTGGTTGTAATTCTATTGCTTTCTTGTAAGAACGAATAGACTTTTCAATTTGACCTTGGGAATAACACATATCCCCTAATCTCTGGTAAGCTTCAGCAAAATAGGGTTGATTTTTAATAGCTTCGTAACAAGCTAAAATCTGATTATCTTGACTAGCTTTATTTTTATTTTTTCTTTTATTTATTGCCTCAACTTGCCCTAAAGAAATACCCAAACAAGAATTTTTTTTACTAGGCAAACTAGCCCGATTAAATAGTTCTTCATCCTGCCAAAAAATAGAAGTACAAATCTTATATTTTTGAGTAGGAAGTAATCCGTAAAAATCTAACCGTTTAAATTTTCTTTCTTGGAGAAACTCCAGGGACGCATCACTTTCTTCTCGATCCGAATTATCAAAAATTATCAAGCCATTTGCTGTTAATTTCCGATAACACAACTCAGCACAACGTCCCCTATTAATTCCATCAATTACAATTATATCAAAATAACTATCATTATATCTATTAATTTCAGCAGCATATTTTTCTTGATCTTCCAATAAAGAAAGTATGACATTTTCTGGGGTATAACTTTTTATTTGACAAAAATAATCAGGATTATGTTCTACAGAAATTACCTCTTTTACTCTTTGAGCATACCACAAAGTTGATTGCCCACTCCCATATTCAAATACTCGGAAATCACTCTTTAATTTATCTTCAATAAATTCAATAGCAGGATAAGAATACCAAGGCAAAGGATTAGAATTGTAATCTATTGATTTTCCCTCTTTTAACGACTTCAGCCATCCTGAAGTTTCTAGATAGTTCAAATTAGTCATGTCAGTTATTACTTATGGCAGTTAAGGCAAAGATTAAGGCACTTATAAATGCTAAAGTTCAGTCAGGTATGACTCCTTAATGATTTAAATCTTGAATTTTGAATTTTGAATTTTAACTCCTGACTTGCCCGTAGCACTATAGTTAGGAATGTGATAAAATATTAAAGATAAGTTAACATAAGTTAATATACAAAGATTGAATAAAATAGATCCCATATCCTAAAAAACTAAGAGGAGTAACTAATTGTGAATAATAAAAAGTGGAGAAACGCTGGCCTGTATGCCCTATTGGCAATAGTGGTCATCGCTTTAGCAACAGCATTCTTCGATCAACAACCCCAAGCTCGCGAAACCTGGAAATACAGTCAGTTTATTCAGCAAGTAGAAAACAAAAATGTAGAGAAAGTAGATATAAGCGCTGACCGGACAGTAGCTAGAGTCAAAGTAGCTGACGGCAGTGTAGTCCGAGTTAATCTACCTAATGACCCGGACCTAATTAACATACTCACTCAAAACAATATAGATATTTCAGTACTACCTCAGAATGAAGAAGGTTTCTGGGTCAGAGCATTAAGCAGTTTATTCTTCCCTATCCTATTGTTGGTAGGATTGTTCTTCCTACTACGACGGGCTCAAAGTGGACCTGGTAGTCAAGCGATGAACTTTGGCAAATCTAAAGCTAGAGTGCAAATGGAACCTCAAACCCAAGTCACATTTAGCGATGTAGCAGGTATTGAACAGGCCAAACTAGAACTAACAGAAGTAGTAGACTTCCTCAAAAATGCCGATCGCTTCACAGCAATAGGAGCCAAAATTCCTAAAGGTGTACTATTAGTAGGCCCTCCCGGAACAGGTAAAACTCTATTAGCTAAGGCTGTTGCTGGGGAAGCAGGAGTACCATTCTTCTCCATCTCCGGCTCTGAATTTGTAGAAATGTTTGTAGGTGTAGGTGCTTCCCGGGTTCGAGACCTATTTGAACAGGCCAAGTCTAGTGCTCCCTGTATCGTATTTATAGATGAAATAGATGCAGTAGGTCGTCAAAGAGGTGCTGGTTTAGGTGGTGGTAATGATGAAAGAGAACAAACTTTGAACCAGCTACTCACCGAGATGGATGGCTTTGAAGGAAACACAGGTATTATTATTATAGCTGCTACTAACCGCCCTGATGTTTTAGACGCTGCCCTACTCCGCCCTGGTCGTTTTGACCGCCAGGTAGTAGTAGACCGCCCCGACTATGCAGGTCGTCTTGAAATTCTCAACGTTCATGCTCGTGGCAAAAGTCTCTCCAAAGATGTAGACTTAGAAAAAATTGCCCGTCGGACACCAGGGTTTACTGGTGCAGATTTATCTAATCTATTAAATGAGGGAGCTATTCTAGCAGCTCGTCGCAATTTAACTGAAATTTCTATGGATGAAGTTAATGATTCCATTGATCGGGTATTGGCTGGCCCAGAAAAGAAAGATCGAGTAATGAGCGAGAAGCGTAAGGAGTTAGTGGCATATCATGAGGCTGGTCATGCTTTGGTTGGAGCTTTAATGCCTGATTATGACCCAGTACAGAAGATTAGTATTATTCCTCGTGGTAGAGCTGGTGGTTTAACTTGGTTTACTCCTAGTGAAGACCGAATGGACTCTGGTTTGTATTCTCGCGCTTACCTACAAAATCAGATGGCTGTAGCTTTGGGTGGTCGTCTTGCTGAGGAAATTGTTTTTGGTGATGAAGAGGTCACCACTGGAGCTTCTAATGATTTGCAGCAAGTGGCTCGTGTGGCCCGCCAGATGGTAACTAGGTTTGGAATGAGCGATCGCCTCGGTCCTGTAGCTCTTGGTCGTCAGAACGGTAATATGTTCTTAGGTAGAGATATTATGTCTGAGCGTGATTTTTCTGAGGAAACTGCTGCTGCTATTGATGATGAGGTTAGTAATTTGGTAGACCAAGCTTATCGTCGTGCTAAAGAAGTTTTAGTAGGCAACCGTCATATTTTGGATAGGTTGGCAGAGATGTTGGTTGATAAGGAGACTGTTGACTCTGATGAGTTACAGGAGTTGTTGGCAACTAATGATGTGAAAATGGCAGCTTTAATTTAGCAGTTATCTTGTAAGGTAGGATGCGTTAATAGAATATAACGCACCACCTCTGCCAAATATTTTTATCCCAAATATTTTGGTTAGTACGTTATGCTTCCTAAATATTAGTCTCCCGATAATAGTAAGTTCTTACCCAATGGTCAGTCAGTCAAATTAGGATTAAATAAGTCTTTGCAGGGTGCAGCCTTTAGTCAGTTTCTTCAAATTTTAGAGTATGTAGCCTGGAAGCTTGGCAAAAAAATTATCAAAGTAGACCCAATAGGTACATCTCAAAATTGTTGGGAATACTTAAACAAAGTCTCGAAAAGCTGATCAGAGCCTTTCGCTGTGCGACACGAAACCTATTCATATCCTAAATTTAGACAGAAACTAGACAGAGACAATAAATGACCCACCCCTTCAGCTAGGAGTGGGTAGTATTTTTATAAAAAAAAGAGGAATACATTACCTCAGCTCAAAATAGCAGTCAAAGCCCCTCTAGTTGAAGATACCCACATTGTCCCGTAAGCGTAACTTCCAGAATATTTCAAATCTAATCATCCTAAAGAAACAAAAACATATCTACCCATTTAATTTTTATTCTTCTCTTCCATAGAAATTTCTATTTGCCTAATATCTTTTTCTAATTCATCAAACACTACTTACTCATCAATTATTTTACCTCACTTTAGTTATTCAATTACAATTGAAATAGAAAGTATAAATTGTTTAAATATTCCTTGATAAACCTTTTCTATCTCTGCGAATAATTATCATTATTTTAACCCACAAATGCCAGATTATCCTGATAGTTTAAACTCTCCATTTATGGTTAAAAAAATTGTTTTATATCTGGCGTTTAGACAATATTTATAGTTTTACTTATTACTAGAATTTAAACTAATTTAAGCTAACCTGAAACTTGTCGAACTCACCGAAAGACAAGCATCAAAACTTACTAAAACTCTTTCAAGCATCAGCATTATAATAGCTTTTAAGTTTATTTTTCCCAGCCTGTCCTATAGAAAAAATTAAGCGATCGCAAAACTTTTGAAATAATTTGAATAATACAAATATTATCCAAACTCATCAAAAAAGACAAATAATATTAATCACTAGACACCTCCAAAAATTTTTCAAATCCTTCTTTCCCTTGACTAAGGATTCTTAATAATTGTAAAAAATACATTATCTAATCGAACGCCATTCTAAATATTTAGAGTATTTATTATTAATAATTCAATATTTTATTGCCTCTTTTTTTTAAACTAAATTCTTTTGAATTTATACTAAAATCAAGCTTCCTATTCTTAATCTAACTAAGCCACATATTCTTATAAATACTTTTTTATAATTACCATCTCTTAACCTGAAGCTTTCCCTAACTAATCAAAATATTTTTATCAATCTAATCATATATTCTATAAAGATTATTTTTTTTCGCTTTTTTTAAATTTTATTGTTTGATTTATAGTGAAATTTATATTTTTTATTGCCTTTTTATTAGCTTTATGTATCGTGATTTTTAAGGCAATGGCAATTTTATATAATTTATCGACCTATTTTTTTAATTTGGATTAAATTATTTGGTTATTTTTTAAGTAAATTCATATCAATTTTTTACCCTCCTTATTATATGAATACATCTACTATTTATCTTATTCAATAGTATTTATTACTTTATTTTTAAATGTATACTTTTTCTTTTTTTTCAGATTTTTTTGTTCTTGTTATCATCATTCAGCCTACTTATACTTTATTTTGTGCTATCTAAAATTAATTCTTATTCTATTCTTAATCTGAAGCCTTCCCTAACTAATCAAAATATTTTTATCAATCTAATCATATATTCTATAAAGATTATTTTTTTTCGCTTTTTTTAAATTTTATTGTTTGATTTATAGTGAAATTTATATTTTTTATTGCCGTTTTATTACCTTTATGTATCGTGATTTTTAAGGCAATGGCAATTTTATATAATTTATCGACCTATTTTTTTTATTTGGATTAAATTCTTTGGTTATTTTTTAAGTAAACTTATATCAATTTTTTACCCTCCTTATTATATGAATACATCTACTATTTATCTTATTCAAGAGTAGTTATTACTTTATTTTTAAATGTATACCTTTTATTTTTTTTCAGATTTTTTTGTTCTTGTTATCATCATTCAGCCTACTTATACTTTATTTTGTGCTATCTAAAATTAATTCTTATTCTATTCTTAATCTGAAGCCTTCCCTAACTAATCAAAATATTTTTATCAATCTAATCATATATTCTATAAAGATTATTTTTTTTCGCTTTTTTTAAATTTTATTGTTTGATTTATAGTGAAATTTATATTTTTTATTGCCGTTTTATTAGCTTTATGTATCGTGATTTTTAAGGCAATGGCAATTTTATATAATTTATCGACCTATTTTTTTTATTTGGATTAAATTCTTTGGTTATTTTTTAAGTAAATTTATATCAATTTTTTACCCTCCTTATTATAAGAATACATCTACTATTTATCTTATTCAATAGTAGTTATTACTTTATTTTTAAATGTATACCTTTTCTTTTTTTTCAGATTTTTTTTGTTCTTGTTCTAATCATTCAGCCTACTTATACTTTATTTTGTGCTATCTAAAATTAATTCTTATTCTATTCTTAATCTGAAGCTTTCCCTATCTAATCAAAATATTTTTATCAATCTAATCATATATTCTATAAAGATTATTTTTTTTCGCTTTTTTTAAATTTTATTGTTTGATTTATAGTGAAATTTATATTTTTTATTGCCGTTTTATTAGCTTTATGTATCGTGATTTTTAAGGCAATGGCAATTTTATATAATTTATCGACCTATTTTTTTTATTTGGATTAAATTATTTGGTTATTTTTTAAGTAAATTCATATCAATTTTTTACCCTCCTTATTATATGAATACATCTACTATTTATCTTATTCAATAGTAGTTATTACTTTATTTTTAAATGTATACCTTTTCTTTTTTTTCAGATTTTTTTGTTCTTGTTATCATCATTCAGCCTACTTATACTTTATTTTGTGCTATCTAAAATTAATTCTTATTCTCTTCTTAATCTGAAGCCTTCCCTAACTAATCAAAATATTTTTATCAATCTAATCATATATTCTATAAAGATTATTTTTTTTCGCTTTTTTTAAATTTTATTGTTTGATTTATAGTGAAATTTATATTTTTTATTGCCGTTTTATTAGCTTTATGTATCGTACTTTTTAAGGCAATGGCAATTTTATATAATTTATCGACCTATTTTTTTTATTTGGATTAAATTATTTGGTTATTTTTTAAGTAAATTTATATCAATTTTTTACCCTCCTTATTATATGAATACATCTACTATTTATCTTATTCAATAGTAGTTATTACTTTATTTTTAAATGTATACTTTTTCTTGTTTTTCAGATTTTTTTGTTCTTGTTATCATCATTCAGCCTACTTATACTTTATTTTGTGCTATCTAAAATTAATTCTTATTCTATTAAAAATTATTGTATCCATAAATATTTATCTTCTTTTTCTGATAATTTTTATAATCAACTTTGTAGCAATAATTATCTCCACATCTACCCAAGAATAAAACATATTTTTAGCAGTTAATTCAGTTGCTTCAAAGTTAATTTATAGGATTTAAAATATTTGTATATGATGTAAATCGTATAAAAGTAAAATAATTTATTATTCCACTTTTAATCTTTTTTTCTACCAACCTCTGATGTTATAAATCATTTTTTTATCTGAGCTAAATAGGTAAGTATAAAAACTTAGATATCTTAATCTTTTTATACTGACTTTAAGAGCTTCTGCACAGTTAATTTGAAGTGAATTTATATCATCTTAATCGTAAAAAAAATCAAAATATACTTATTTATTGATTTATGCTCTTTTATTTTCAGATATAAATTGAGAATTTCCTATTAATTTTTTAAATCACTTAGTATTAATATCTATAACTATTTTGGCTTCTTTTGGGTAGTAATTTATATACTCTAATATTTTGTTCATTAGTATATTTTTTCACAAATTAACCCCAAGATTATAGCTTAATTTTGATTTTGGAGACATCTACTTATTACATACCAAAAGCTTATATTAATCTTTAGTTATAAGTATCATGTTAACATCCTTCTCAGATTTATTTTTTCCTTGCTCCCAGAATTTAGTCTCAACTCCAGTTATTATCTAAATATTCTTTTGATACTAATGACAAAAAATACAATAAATATTTATTTAAAATAACTCAGATATTGTTCATATAAAAAGCAAATATAAAAAAAAGTATACAAATATTATCAATAATATTTTTATGGAATTAAATTATCAATAAAACTTCTTCAATTTCATCAAATAATTTATTCATTATGGCACTTAAATTTGCAGGCTTCTTTAATAGTAAATGGGGAGAACCTATTCCAGGGAAAGATAACCAAGCTCCAGTTTTTGTAGGTGTTGATACTCACTCATTTAAATGGGGATCTCCAGCAAACTCTCGAACATACCCAAATGAACTGAGCTTTGTCATCGATCCTTTTTCCACTCAACTAAAAGTTCAAAGTAGGAGATTTAATCTACTTTAATGGCTCAGTTAATACTAATACAAGTGTTGAATTAGTACCCCTGGATATAGAACTAGAATTATATGACCCAATTAGACGTACCGAATCTTTTGAGTTTGACTTTGATATTGTTGCAACAACTAACACCAGCAACCCTCAAGAAAGTGCTGATTTTGTTTTTCCTCTTAACAAAGTTACTGATAGTAGTTTCAAATATAAAGGAAAAGATTATACTATTAGAATACTCGGCTTTAGTCAAGATAAAGGTCGAACATTTACCCGAGAATTTCGAGTATTAGAAGACGCAAGAACAACAGCAGGTCTGTACGCCAAAATAGAACTTGATAAAGGAATAGGAACTAGTAGAGCAGACAAACTTACAGGTAGTAACAGAGACGAAAGATTAGATGGAAGAGGAGGAAATGATCAACTCATAGGTAGAGGAGGAGATGATATCCTCATTGGAGGAAGCGGTAAAGATAGACTCAACGGAGGAAGTGGTAATGACAAGCTTAATGGTGGGGCAGGAAATGATACTTTGACTGGTGCTGCAGGTGTAGATACTTTTGTTTATGACACAGGTCGTAATTTTCGGAGACGAGATATAGGTGTAGATAAAATAGTAGATTTCATGTTAGATGAAGATACCATTGTTTTGTCTCGAACAACCTTCAGCAAAATAGAAAGTTTAGCTGGAAGTATACTTCAAGAATTTGAGGTTGTTGATAGTAACAATGCTGCGATAAAAAGTAATGCTTTTATTGTCTATAATCAAAGTAATGGCAATTTATATTACAACCAAAATGGTAGTAATAATGGGTTTGGTAGTGGTGGTTTATTTGCTCGTTTAGAAGGAAGACCTGCACTAGAAGCAACTGACTTTTTTATTGATAATTAGACTCTAGAAATTTGTAAGTATTTAGCTGGAAAATATACTATTTGTCAACTCATCTTAACAATGATTGACAAATAGTATATTTTCTAATCTTATTGCCCTGATAGCTTTTGAGATTAATTTAGTGACGAAAGTACATTCCAATTGTTAAGCTGGGAAAATCAATAAGATGAAAATTCTCTGATATTTATAATTCCTTGAAAAAATTGTATTGCGATAGAATTATAAAAATATTTATTTGTCAATAAAATTTTAGATGAGCTTACCCTGGGAAAATATACCCCATTAATTAGTAACTGCTATTAACAAAGAATATGTATCCTTAATGAGTGAACTTGACCACTATCACTGCTAATATTTTCCTTGGCATAATCCCAATAATTCAGTTATTTTATTGTTCTGACACAATATCAATAGGTTTCTCTTTCTTAACTATAAAATTTCTTAGCAGAGGGGCAACAAACAGGAGAATTAACATTCGAGTAAGTTGAATTCCCAAGACTAAACCAGCATCGCCACCTAATTCATTAACCGTAGCAATCATTGCCTCCAATTTCTGCCAAAAACTTTACATGTAGCAGCCCCCATTAATCTTAGAACATTCTCACACCTCTCAATTTTAGTCATAGCAAGAATTTAACTTCTGAGTTCTGAATTCTGAGTCCTGAGCTCAGCTATAACTATTGCTAGATATATCTAAAGGTTCTAAAAGACTATCATTATAAGAACCAGAAAGAACGTGGTTTATGCAAAAGCCACTACCATTAAGAATTCGATAAGTGTGAGCTACACCTGCTGGAATAAACACACTTGCTGGACTATCAATTTTTTGAACAACTTGTCCTAGACATACTTCAACCTGCAATCCTTTCATACCAAGTTCGTGACCTAAAAACAAGAACAAGCTATCTACATAAAGAGTCTGAACATCCACATAAGCAAGAGGTTTTTCTTCCACCACTCTTATTTCACGTACAATACAAGATTGCCGACAGTTTGGAACCATGCACTCATCAATCATCAAATGTCCTACACTATCTCCATATCTATGATATCCAAGCTCACTAGCACACTTTACTATTGGTGTAAGAAATAAAGAATGAACAGAGGGTATGCTTTTACCAGATAACTCCATAGTTTTCCCCACATATTCTGGCAAAATCCAGCTATAGCTAGAAGGATCACGTTTGACTGCTTTTTGATGTAGATGAGCAGTGTGAATAAAAGCATTCCCCCCTGAGATTGGTTGGTTAAAATTAACAGGGTAACGCGAAAAAGCTGCTACATACTTACTTGTTCGTTGAATTATCTCTCCTGACGGTAGGGAACGCAGTCCCTTATAATAAAGATTAACTAACAGACCTAATGTATCAGTTATGCCACATCTTTCCCCTAACCCGTTAACAGAAGAAGAAATCCTTTCTGCGCCAGCATCAGAAGCAGCAAGAGCATTAGCCATTGCCAAACCCCGATCATTATGAAAATGGACTTCTAAAGGTACTGTTGAAAAATCACTCTTCAACTTTTCAATCGTCTCAGTAACCTCATTAGGCTCCATGATTCCTACTGTATCAGAAAAGCAAATGCAATCTGCACCAGCTTCTATAGCTACACTATAAACGCTTTTTAGCAAACAATAGTCAGTGCGAGAAGCATCTTCAGCAGTATATCTTACCTTCAAACCAAGGGTTTTGGCATACATTACTGACTCTTTGATGCAGTTAAAAATTTTGCTAATAGTCCATCTCGCACGAGTCAGCCTAGTTTCTTCATTAATTCCCAAGAATATACCAACCCATTGAGCCGATGTTTCTTTGACTGCCTCAATATCAGCTAAATTAGCACGTGCATGAGCAATAACTGGGCAGAGATTTGAAGCTACAATTTCTCGGACAATTTGTTTTTGCTCAATAGAAACAACAGGGTGGCAGACTTCAATTATATCAATGCCCAGACTATGAAGTAGTTTAGCAATCTTCAGGGATTGTTCCCAACTAAAATTTATCCCAGGGGCAGTCTGCCTTCCTTCTCTTAGGGTGCTATCTACAATTTGAACCATTGTTGATTTTTTTTTGTTAAATATAGTTATTTGCAATTAACAGTCTATAGATTGACGTCTAGGCCAAAGTTTTTCAGGTAAATTAGGCCAAGGTAAAAGTCCAATTTATATTAGGAGTAGAGTTGTTAAATAATTGGATCTAAATGGGCAGTAATTATCAAGCCACCACCATTAACATTAATAACTTGACCATTAACAAAGCCACTACAATCTGAAGCAATGTACAAACAAGTTTCAACTATATCTTGACAAGAAGCAAGACGACCCACAGGAATCATTTTTTCCATAATTTCGTATTTAGTGTCTAAATTGGGGTAATCTTTAGAAATACGGATAGTATCAATTGTCCCTGGACTAACCCTCTTTGCAGTAATTCCGTAAGGTCCAAATTATGTAGCGATCGCTTTAGCAAAAGCATTAAGACCTCCTTTACAGGTAACATTATGAGCTTGGTATAGTGTACCTATTGAACCATAATAACCAGAAATATAAATAATCCGACCCCATCTTCTAGCTTTCATCCCTGGAATTATAGCCTTAGCTAGATAGAATGCAGAATTAAGGTTCGTTTTAATTACTTCATGCCAATCTTTAAGGGAGATATCTAAAAAATTTTGTCTTTTTTCCAGGGAAATATTAGAGACAGCAATATCAACTGCACCAAACTTTTCAATAGCAAAATCAACCATTTTTTGTACTGTATCAGGATTATTCACACCAGCCATCACCGCTATTTCTTGATCCCCCTAAATCACGAGTTTTTTCAGCAACTTCTTCCATCGCTTTTTAATTGCGATGACCATCAATCACTACATTGGCACCAGATGAGGCAAATAATAACGCGATCGCTCTTCCAATATTCTGGCCTTAATCTGTCAGTCTAGCGGTTCTACCTTGTAATGTCTTATTTCTATCTTTCATTATTTTGTGATTATCAAGACTTGAATTATTTTACAGTACGCTGATTAATTAATACTCCTCTGATATTCTGGTATTTTAGAAAATTAATTAACTATTGCTCTATACGCAATAGTCAGAAAATTTCTAGACTCATCTCTGGTATCTTGGTGCTTCAGAAAATGAATGAATTAACTATTGCGCAATAGTTGGAATATATTATAACTTACCCCTGACATCGTGGTGCTTCAGAAAATGAATGAATTAACTATTGCGCAATAGTTGGAAGACATTATAACTTATCTCTGGCATCGTGGTGCTTCAGAAAATGAATGAATTAACTATTGCGCAATAGTTGGAATATATTATAACTTACCCCTGACATCATGGTGCTTCAGAAAATGAATGAATTAACTATTGCGCAATAGTTGGAAGACATTATAACTTATCTCTGGCATCGTGGTGCTTCAGAAAATGAATGAATTAACTATTGCGCAATAGTTGGAAAACATTATAACTTATCTCTGACATCGTGGTGCTTCAGAAAATGAATGAATTAACTATTGCGCAATAGTTGGAAGACATTATAACTTATCTCTGGCATCGTAATGCTTCAGAAAATGAATGAATTAACTATTGCGCAATAGTTGGAAAACATTATAACTTATCCCTGGCATCGTGGTGCTTCAGGAAATGAATGAATTATAGTTATATTCACTCTTCATCCCCTCTAATGGAGTATTTTATGGAATTACTTACTATTCTAGCAAGAGAAAGTCATTTAAAAATTTGCTATTGCATCGTTTTAGATGCAATAGCCCACTACTCTACTAGACTAACTCCTCTCACACTTCCCTACTTCCTACTCCCCTACACCCTTCCTAAGTATACAATTAGCATCCAAAACAAATAAACTATCACTCTGAAAAACAACACAATTAGATATAGTTGTTGCCAAAGCAGGAATATTTCCTAACTGCAAAAAAGTAACCGCCTCTTGTGCAAATTTATATTGCATTAACCAACTATTATCCTCAACATATTCTGGCGTAAAAGCACCACGATGTACCATCCAAAAATCAATTCCATACTTTTGAATAAAATCTTTAACATCCGTTAAATCCGAACTATATTGAGCCACAATTAAATCTATAGTTCGTTCGCGAAATTGACTATAATAACCAACTTGATAAGGAATAGCATATTCCCTACCCAACAAAATAGAACGTTGAGCAAATGTAGGTAATAAATTCGCCTCTTCTTCCAAAGAAGCAATCAGAATATCTTTAGGTTGTTCTTGAAAAAAATCATATAAATATGTAGCCCTTCCCACCTTATATTTAACCAGAGGAAAACCTTTAACAAAAGAAGGATATAACACCAGAGATGCCAGAATTAAACCTATTAAACTTAAAGAAATAATACCCCGAAATGCAACAGGAAACTTGTGTATATTTTTTGCCCAATTAAATAAAGCATCAATAATCAAAGTAAGAGCGATCGCCGTTGCCAAAGCAATAATTATGCGGAAACTTAATCCTGTATATCTACTAGGAAGATGTAGTCGAAAAAGTAAGACGTGGGCAATAAAAAACATTCCCAAAGATGACAATAATAAATGCAGTAATAACCAAATACGGCTAGTAATATTTTTAATTAAAGGAAAAGCAGAACCAAAAGACAATAAAAAGGGTAATACTAACCCCGCACATTGAGTAGCAGGAGTAAACAAAGACTTAGGAAACATTCCACTACGTTTGCCAGTTAACCAAAAATCTTTTGGATGAACATGAAAAAATGTACTCCTCCCATTGGGATAAAATTCTCTTAATTTCATTGCTGCTTCTCGACTAATAGCAGGTCCGAATTCCGAAGAAGTTAAAGCATAAGGTAATAAAATAAAAAATGCCATACTTAAACCCACTCCACAAAATATAAAATCTTGTTTTTTCGATGAGAATTGAAACCTGCCATTTCTCCAGCAAATCAACCTCAAAATTAACATTCCAGAAGCCACAAAAACATACTGTGGATAAAATAATCCCACCAGAGCGATCGCTATCCCCATTCTGACTAAAGAACCACAGATTAAATAATATAAAAAAGCCATAAAAAATGGATAAACAAATGCTCTAGGCGTAGCCGAAGCCACATCATCTTTCATCCAAATAGCCTGATTCATTACCAAAGTAGCAATAAACCCTGCCATTGGGACCGGCAATATTTCTAAAGTAATTCTAAAAATATAGTAAGTACAGATTAAACCCAAGATAAAAGGAATAATTTTTGCTAAAATCAACGGATTAATTCCTACAAATGCTGCACTTTTATAAAGCCAAGTATATCCGGCTGGAGCCACCGACTGAAAATAGTCAGCAATTAAATCATTAGGAAATAAATCAGGATCAAAAAAACGTTGCATCCAAAAAATATGTTGTCTAGCATCATCTTGAACACTAAGGCTACTAATAAAAGCTTTTTTAACTGCTAAAAAACCATAAATAACAGCAAAAGTCATGCTAATACTAAACCAAAATATCACCCCTTGATAGGATTTTTTATTAATAGGATGAGTCAAAAATTTATGTAAATTTGAAATTACCATTTACTAGGAAAAATTTATTAATTAAGCTAATTTTAATAGATATTTAAAATATTTTTTTCTAATTTATTAAGCTAATCTTGAATCTAAACAGTTTCACCAAGATTGACAATAACTACCCCTAGTCCCCCATTCAATCTATATTATCTCTTCCCCTTTAACAATTAGTCTATTGCTAGTAGTTTGAAGCCCTACCTATCTTCTGCCTTTGATCATCCCTTTAACTAATTCCCTCAGTCCAACCAATGTAATTGATTTCGAGTACTTTGAGTCCGTCTCTATGTTTACTTTACTTCTACCCTAAAAGCAGAATGACTGTTCCATAGAGCTTCCTTAGCTGTGTCCAACCCATACCCAGATTTTCATGAAACTGCTAGATTCTTCGCTAATATCAATCCCACCCTATTAGACATCTCCAAAAATACTCAAACGCTTATACTAACTATTTTTAGTGGAGCGTTAGCTCACCTTGAAGATAGTTAATTTGTACAGTTTTATGGGCATTAGAGATACTTCGTATTACTAATTCAAATATTTATTAGACTTTGATTTATTATTTTTATCTCAGTTTTTGATGATTTTTAATAATATAAATGAGCCAATTATTATTCACACTAAACCACATATTGTTAAAATTAATTTTTGATAATTATTATCTTTTAATCTAAATCTTTATCTAGGAAATTTAAATATTTTAATTAATCTTATTACATGTTATACAAATATTATTTTTTTTGCTTTTTCTTGATTTTCTTCTTTGATTTATGGTAGCATTTATTTTTTTCTTAGTTTCTTTTTTAGTGTAGTAGTTCTTTCTACTCCTTCATCAGCTTTATCTCCTTAAAATTTTTGTTTTTCATCAAATTTATCCGGTTGTTTTCTTAATATTTTTACATCACTTACTGGACCTTTTTCTCCTACTATTACATCCACTATTTCTGTTCATTTTAGTGTCGTTATTATTTTATTTTTAAAAGTATAATTTTTCTTTTTTCATATTTGATATTTTTCTTGGTTTTTATATTTAATTAGTCTTTCTATGCCTTGTTATGTACTATCTACAATTAATTATAATTCTGTTAATATCTCCTTTACCCATTCCAATTCATTTTCTTTTTTTTTACTTGTTATAATAAACTTGCTGGCAGTAATTATCTGAGAATATCTATCCAGTAATGAAAAATATTATTAGCACTTCATTCACTTATACCAAAGTTAATTCCTAATGTTTGAAAACTTGGTATTTGATGTAAATAAAATCATGTTAAAATTATTTATTCTTCCTTTGTTAAATTCTTTTTTCTGACTCCACCTGCTTTAATTAATCTTTTTTCTGTTTTCGCGATCGCCGACTTTTTTATGATTCTATTCTTGGGGCATTTTCTATTAATTTTATTAGCTGTTCATAAGTAATACCAATAATTCTTTTTGTTTATTTTGGATGATTATAAATATATTCTAAAGTTGGATTCATTTGGGAGACTGTATACATAAATGGTTTTGATAATTTTACCTTATTTTCTATTTTAGAGATGTCTATTAGATTTTGCCAAGACTTTAAGCTTTATAGAGTACTGCAGTAGATAGGCAAAACCCTGCAAAGTGATACACAATATCAGCATTTTTCTGTAACCGAGATCAAGTTTGTTCTCAGTAGCAAAGGAGAGCGTTCATCCCAAGTTTTACTGTAGAAATATATAGTAAGGGACATATTAATTAGGACATCGTATTTTGATTAAAAGGCAACAGAAAAAAGGCAACTGCCAACAAGAAAGTATCTTAACAGTTGTGGCGGCTGCTATATATAGTTTTACGCATTAAAATTAAGACATTAACTATCATAGATAAAACCTTAAAAATTTATTTTATGAGTATGCCTAGCCAGTATCTCATGACTATTATCTCTGAAGCAAAGCAATTAAAGCAGTAAAAAGAAGACAAAAAAAGCAACATGAGTCTCAAATGCTAAATATTAGCCATAATACAGATTTATGGTTAAGTAAAGAAGAAGAGGTAGGGGATGATCAAGCAATTACCAAGAAAAGAAGACCACAAAGACTTAAAGACGAAGAAAAACTAAACAATTTATCATAGAAAATAAAGACAAAAATCAACAGCAAATGGCAAAACTATGGGGAGATAATATTACTCAAAAAAATATTAGCTATTTCTGTCGAAAAATAGGAATTATGCGTAAAAAAAATTATGGATATGAATAAATAGACAAATAAAAAAGACAAAAATTTAGGGGAAAATATCAAAATTAGAGAAAAATAAACTTTTTTTATGTTTATGAATAACCACTTTATAATTGAAACAATTATTCTGATAGGTATAGTCATAAAAGGGAGAAAATTTATACCTTAAAATTAGGAAAAAAAAGAGAGAGAAGAAGTTAAATTTCTGGGAGGTGAAAAAAAATTGAAAAAGCCTTCAATATCAAATAGCACAACTAAAATATGATCAAAAAAGATGAGCCTATATATTCTAAATAAGACTTATTTAATAATAATTAATAAACTAGATTATTTATATAATAAACATTTAAAAAAATAAATTAAAATTCAATTTTTGGTTAATGTTAAAAGTTTTGATTGCTATAATTAAAGAATACCGATAAATAAGTTGATAAAGTCTGGCAAATTAAATGGAAAACATATAAATTTTTAGAGTCGTTATCGTGCTATGCAAAGGTTTTTATAATTAAAAATACTAAGATTTTAAATTCTATGATTTTCAATTTTAGTTGTCGTGCTATGAAAGGTTTTACCATTAAAAATACTAAAATTTAAAACTCTATAGTTTCCAATTTTAAAAGATTAAATTCAATCAAACTTTGAAGCTAGGAAAATTCTAACAATTGCGATAGATATAAATCAATTTAATTAGTAAATTCATGATTTATAAGCCCATTTTATAACCGTCATAGCATATAAATTTACATTACTAATTTTGACAAAAAAGGAAGTTCAGCTCATCTTAACAATCATTGAAAAATAGTATTTTTTATGAGTCTATGAGCCTAACAGATTTTGAGATTAATTTAGTAACGAAAATATATTCCAATTATTAGGTGGCAAAAACCGATAAGATGAAAATTATGTGATATTTATAATTTCTTGAAAAGATTGTATTGCAAGCAGATAATCAAAATATTGATTTGTCAATAAAATTTTAGATGAGCTTGCCCTGGAGAAAAAAAAGGAATAGTAATTTTAGGAGACAGCAAGAATCTTTATCTAAAGTTTTAGCTTTATTTTCTGATTTCCAAAAAGTAGTTTTAAGAGATAAATAATTTTGTAGTATGAAACTATCTAAATATTTAAAATTCAATAAAAGACATATTTTTGTTTTATCTTGAAAAAAAGCTTGTATATAAAAATATCAAAATAACTGTAGATAGCTCTAATAGAATTAGGAATAAAGCCGAGAATATCTTTATATTTTGAATGAAACAATATTAAGAACTTCAAGTTTTTTATGCTGATAAATATTGCAAAAAAAATACAATAAAAATATAGAGAAAATATGACAGGAAAGGCATAATTTATATTAACAAATTCATGTGATTTAGAAATAACAATAAATGCTTATGAAAAAAATACGGATATGTATTGAATAAATGTTTTAGCATTTTAAGAAATTAGGGTATAATTGGAAAAAGATTCAAGTCAAAGGTGAAGGATTAATTTCCATCACATTATTGATGACTTTAGCTTATTGTTAATACTTAATTTTTGGAAAAAGAACTTGTGAAAAAGGAGTAGGAAATTATGTAAATTGTCTAACTTAAAAAGGAAGAAAATATCGACGAAATAGCCATTTTCCTATAGTAAATAAAGGTCAATTTTAGTTAAATTCCTTGTTTATGTTTGTAGAAGAAGCAGAGGAATTGATAGCCAATTACCCTCAAAAAACGGCTCAATTATCAGAGAGGTATAAAAGCTACAAACCATGTTATGTCAACTTTTTAGTCCTACCTATGACCCCTTCAGGTAAAATTGGGACCTCAAGAGAGAAAAAGTTATTTGGACCTTAAACCTTTGAAGGTTAATATAATCGTTATTTATTTGAGTTTTGGCTGTAGTTTTATCTCATACCTTTCAGAAAGGGGAGAAAATAAAAAAATGTTAGAGGAAGCAGTTTGTGAAGCTTGGTATCTGCTACCTTCTTCCCTAAAATTAAACAAAATTGAAAACTAGTGGGCAGTTTTAAAGATATAGATAAAACAAAGATTAAAGGAATTTGAGAAAGTTTCAAATTGTGTCGATAGTGCCTTCAAAAATTGTCCGAAAGTTTTTGGGTAAAACTATAAAATTGGGGCTTATACTATCGACTATCTATACACAAAACTTATCTTTATAGCACCTACTTTTCATAGGCTAGAAAATATTTTTGATTCTCCTTATATATATGATGAATAAAACATTTCCAGATTTATATCCTCAATTAGAATATGTACTAAAGTATAAAGAAATAAAAGAGTATCCTAATAGAATAAAAAAATCATTAAAAAGTTGTGTTTCTTAGAGACTATTTGTAAAAAAAAAGCTAAAGATAGCTATCAAAAAGTATTCAAGGTAGGAAAGTAGAAAAAATCATGATAATTGTCACATAAATTTCTTGAAAATCTTTAGCCAGGGCTCTAAGCCCTCGCCAGTGAGAACTACTCGAACCTCTACTAAAAAAACCTCTCTCAATGAGGGCCAAAACCAAATGCTAATCAATAGTATATTCTATATTCTTTACTCTAGTTTTCATTGGCGTTCTTTGCCCCAGAAGCTACAACCTTGGCAAACTGTCTCGACAAAATTTCGTAAATGCCACGGATAGGATATGGTGCTTGGGAACAAATCAATCATATGATAAAAATAACATTAATCTTTTTTTGCTGTTACAACAGATTTTGGGCAAATTATGTATATGTATTTTGTCAAAATCATGTAGTGCAAGCATATTGACCGAATTAGAGTACCTCATAATAACAGAAAGCGCTGTATGTTATTACTGAATTTATTGCTATAATTATTGGTGTGATTTTGGCAGGGTTTATCGTACATTTTATTACATAGTAAAATTATGACTTTTCGTAAGCTGTCTCTTCTGAAAAATATGTATAAAAATTCAAAGTTATATTAGTACTTTATAAATTAAAACTGGAAAATACAAAGTTCTTCTAAAAAACTATTAGCTATAAAGACTGAAAGTATTATAGGAATAGCTAAAGAAACTGGTTTAACTACCTACAAGTGAAAGATTAAACAATACTTTGACTTCAAATAATTTATCGCACAATGTTAGGAAAACTTGATCTTTATTCTCAGAAGGCGCGAAAATTACTTGGGTGCTATGAGAATATTTTATTAATCATTATAATCAGGCAATGGCTTCACCGTAATTTGATCATACAGGAATACCAAGCATATATAGTAATTAAACATTTTAGGCAGAAATAAGCACTTATAAAAAAATTACCCTCAGTAATTTTATGTGATATTCTAATATATAGCAATCCCATATTGGTCGCAACAGATATAATAGTAAGAATAACAGATCTAAGAAAAAGACAAAAAATGAATATTATAGATAAACTAAATGATTTTATTAATCAAACAAAAGAGTCTAAAGAAATTAAAAGGGCCTTGGCCGTAAAAATGACCTTGTCAGGAAAATCCTACCATGAAGTCAAAGAATTATTAAATGTTTCTCACAGTTTTATTAGTGAATGGAAAAACCAAGCATTATTTCATGGTGTAGAAAGTTTAAGGCTTCAGTATCAAGGGAGACAAGGTTACTTAAAAACGGTCGAAAAAGAGAAAACAATTGAGTGGTTGAGAGCACAAGATTATCTTAGGTTATCAGATTTAAAAAACTACTTACAGGAGCAATATGATGTGGTTTTTGAGTCTAATCAAAGTTACTATAACTTGTTTAAAGAAGCGGGCATAAGTTGGAAAAAAACTCAAAAAAAGAATCCTGCTAAAAATGATGAATTAGTAGAAGTTAAAAGAAAAGAAATACAGGAATTTTTAGCTAAATGGCAACCAGAAATAGAAACTGGAAAGCTTACAGTGTTTATGATTGATGAATGTCATCTTCTATGGGGAGACATATTAGGTTATGCTTGGGGAAAAACAGATGAAAGAATAGAAATTGCAATTAAAAATGAAAAAGAAAGACAGACTTATTATGGAGCTTTAGACTATAAAACCAAGGAATTTCTTGTGCAAGAATATGAGAGTGGAAATACTAAAAATACTATTGAATTTATTAAATATTTGCAGAAGCAAAGACCGGGCAACAAATTGGCAATATTTTGGGATGGGGCAACTTACCATAACTCTCAAGAATTTCGAGAATATTTAATGACAATTAATCAATACTTATCAGAAGAAGAATTGTTGATAAATTGTACAAGATTTGCTCCCAATGCTCCGGAGCAAAATCCTGTTGAAGATATTTGGTTACAAACCAAAAATTTCAGTATTACTTTTTATCATCTTTGCAGTTCTTTTAAAGTAGTTAAGTGGCTATTTAAGTTTTTTGCGGATGGTCAAATATTCAATTTCCCAAAACTTTTTCAGTATGAAATTTTGCCGCAACCTACTTAG

Protein sequences of DBSCAN-SWA_9

>NC_008312|5699407:5783757|5704607_5705693_+|WP_011613105.1|DBSCAN-SWA
MSYIQKLKSLENQKQRIESQIAGLEQLSNKCNQEIKAETSLAQRTQLNTQMDNYSTEINELYNKLDHIENEIENLKLKEKSLSSNDYLDNPKNQQLLKFEQYLYDIDFEKALKTFQRITSQFNKEGDVALFFIEKCLTNRGDLCLKRLKDDLFSETYNIHRQHFRPCFVTYTLGNLEGVIQGIAKFFDVKKEEMTVELVINKIGNSLQNNSVLFIEINCDISQPSDIDPLIPWFINVFWKPLREKVNEVAKDYEGIKVVAVITSNLLLNSRFSNSELSSYYNRKSRIFSRDKLVKIPLEKWKKEDIKKWLTKYGNPRLKNTDKDTIAEKIYNATDKGRPTDVCLALQQKQWQNLIYSNPTY
>NC_008312|5699407:5783757|5752207_5752822_+|WP_011613134.1|DBSCAN-SWA
MNQNLQDKNTFQQNNKSQNYSELSQVTNYYSELSKYEQDDVDTINKLAETYYNKRNFTSAIALCHKALKKQANFAPVYKTLGNILQAQNKIDAAIRAYSLAIKINPNFIEAIVNLASMFYKKGQIDAAMINYRKAIKIKPDFGVAYWNLGKVLEQEGRFYEAFFFQEKALKLQPSLVDNTQNNHQDSHFQKWNNLEGKIGGGTF
>NC_008312|5699407:5783757|5712912_5713839_-|WP_011613112.1|DBSCAN-SWA
MLPIIFSLAGTILSEAEKQLFTRSQPAGFILFQRNCEHPTQVKQLTDTLRKCINQKDIPILIDQEGGRVARLQPPHWWVAPSASSYLQEINDLNDAAHRAKIDAKHIAQDLQNIGINVNCSPVLDCPIPEADLVIGTRAYSNSPSEIITMAKAVIEGFQEEGVMPVIKHIPGHGRALVDSHKALPVVETSLKELSECDFLPFKALAKSVTWAMSAHVIYTAIDSENCATVSPTIIQEIIRKQIGFEGILVTDDLTMKALSGDLVTKVNRSLKAGCDLALYCDGKLEDMEFLADNITPVKPILFSSKIS
>NC_008312|5699407:5783757|5727948_5728101_+|WP_155994479.1|DBSCAN-SWA
MNLIDKSIQVSCLSGCDVTLIQSLVPESPNLEADLPSTISDHKPLLTINY
>NC_008312|5699407:5783757|5722163_5722937_-|WP_011613118.1|DBSCAN-SWA
MNIIPAIDILGGRCVRLYQGDYKQTQIFNDNPVDVAKRWADEGATKLHLVDLDAAKVGQPVNQKTIEAIIKAVDIPIQVGGGLRNYSTVASLLALGVQQAILGTVAIEQPELVSDFCQKFPGQIIVGIDARDGKVATKGWLETSQVLATDLALQMAKLKVAAIIYTDIHRDGTLKGPNIEALRELATAVSIPVIASGGISSINDLLNLLALETIGVKGAIVGRALYTGGISLKEANQAVGQGRWQDVPPNLGSSTFV
>NC_008312|5699407:5783757|5752993_5753275_+|WP_011613135.1|DBSCAN-SWA
MKSEEQQHPQYHKDREIVNTLLAEENTSYNLAELARLKIRYQGFPGAKDIQKDLEEVLAKWKITEEKLYEKTRDIHRKGKAYKQKNTDKEDWL
>NC_008312|5699407:5783757|5745245_5745491_-|WP_071820702.1|DBSCAN-SWA
MQKLIPPIISSIILALWVSSIAILSVQNATPISLKFLSFQSIEIPIGVILSFSVSIGVIISSIILPSLFHLEQIKDHQKNF
>NC_008312|5699407:5783757|5701247_5701946_+|WP_011613101.1|DBSCAN-SWA
MHQTKFWAIAPFGLLTILGKPLLSPALPIHQAVVNFSYVDESSTKSEIFAQDTSFPKVTPSPEMTPTLEDSPSPEMTPTLEDSPSPEMTPTLEDSPSPEMTPTLEDSPSPEMIPPTQEPEIILQQPGMLSDDDLVLPSDESVYDEHTFEGTEGQVVTVTVESPDFDTYLAVFSPDTKLLGEHDDISKKNTNSQLTITLPMTGKYRVIVNSYDKTGRGEYNLQVIQSGQTSDF
>NC_008312|5699407:5783757|5775406_5777062_-|WP_044137774.1|DBSCAN-SWA
MTFAVIYGFLAVKKAFISSLSVQDDARQHIFWMQRFFDPDLFPNDLIADYFQSVAPAGYTWLYKSAAFVGINPLILAKIIPFILGLICTYYIFRITLEILPVPMAGFIATLVMNQAIWMKDDVASATPRAFVYPFFMAFLYYLICGSLVRMGIAIALVGLFYPQYVFVASGMLILRLICWRNGRFQFSSKKQDFIFCGVGLSMAFFILLPYALTSSEFGPAISREAAMKLREFYPNGRSTFFHVHPKDFWLTGKRSGMFPKSLFTPATQCAGLVLPFLLSFGSAFPLIKNITSRIWLLLHLLLSSLGMFFIAHVLLFRLHLPSRYTGLSFRIIIALATAIALTLIIDALFNWAKNIHKFPVAFRGIISLSLIGLILASLVLYPSFVKGFPLVKYKVGRATYLYDFFQEQPKDILIASLEEEANLLPTFAQRSILLGREYAIPYQVGYYSQFRERTIDLIVAQYSSDLTDVKDFIQKYGIDFWMVHRGAFTPEYVEDNSWLMQYKFAQEAVTFLQLGNIPALATTISNCVVFQSDSLFVLDANCILRKGVGE
>NC_008312|5699407:5783757|5772258_5773647_-|WP_011613140.1|DBSCAN-SWA
MVQIVDSTLREGRQTAPGINFSWEQSLKIAKLLHSLGIDIIEVCHPVVSIEQKQIVREIVASNLCPVIAHARANLADIEAVKETSAQWVGIFLGINEETRLTRARWTISKIFNCIKESVMYAKTLGLKVRYTAEDASRTDYCLLKSVYSVAIEAGADCICFSDTVGIMEPNEVTETIEKLKSDFSTVPLEVHFHNDRGLAMANALAASDAGAERISSSVNGLGERCGITDTLGLLVNLYYKGLRSLPSGEIIQRTSKYVAAFSRYPVNFNQPISGGNAFIHTAHLHQKAVKRDPSSYSWILPEYVGKTMELSGKSIPSVHSLFLTPIVKCASELGYHRYGDSVGHLMIDECMVPNCRQSCIVREIRVVEEKPLAYVDVQTLYVDSLFLFLGHELGMKGLQVEVCLGQVVQKIDSPASVFIPAGVAHTYRILNGSGFCINHVLSGSYNDSLLEPLDISSNSYS
>NC_008312|5699407:5783757|5717511_5719536_+|WP_011613117.1|DBSCAN-SWA
MEKGKLIEFRLHGERRLAVADRPDGKKNWVVIEANGKSNSIPPKQISYEVGGESYQSSEIPQFIQEVKTYLDPSSLEVAWELLVEEAEAVNPEEMALLLFSEQTPIQCYAAYILLSDDKLYFKQKGDRYEPRSVAQVAEIKHQQEVQKQRKEELENFLLRVHNRLAGEKVEWEQSDYNRLDIIEKFATHGEETSHRSQAMETLATLKVPETSEAAFKLLVDLGIWSEHENLYLRRSQIPKCFSTKVLEVAKSCLQSLPPDPETNRLDLTHLKVYTIDDESTQEIDDGLSIEFLEDGQHRIWVHIADPTRLLIPGDELDLEARRRTTTLYLPTGMVPMFPPELATGPMSLIQGQVCRALSFGILLDESGAVIDYIIHASLIKPTYRLTYDDVDEMLQLKIKLEPEIHALNDWAKQRFKWRQSQGSISIYMPESVIKVKGEGEEITVEVLDDSPSRQLVAEMMILAGEVGAKYGQENNIPLPYRSQPQPELPPDAELMLLPAGPVRSTAMRRCMPKSEMGTIPARHASLALETYVQVTSPIRRYSDLLAHFQIKAHLRGDPLPFTLEQMQEMVMSLVPAVKEASSVERFTNRYWGLEYLRRNSGEVWQALVIRWLKEEINLGLVLLEELGLELAMRFGRSVEVGDRLEVKVAHADPRRDEIVFQEIVNNVAEKVNN
>NC_008312|5699407:5783757|5730127_5731453_-|WP_011613120.1|DBSCAN-SWA
MSTKPTIAFTHLGCEKNRIDTEHIIGLLVQAGYEVDANEELADYVVVNTCSFIQAAREESVKTLVELAEANKKIVIAGCMAQHFPEELLAELPEAIALVGTGDYHKIVDVMQRVEKGDRVKEVTAEPTYIADETTPRYRTTSEGVAYVRIAEGCDYRCAFCIIPHLRGKARSRTIESIVVEAQKLADQGVKEIILISQITTNYGIDIYGQPKLADLLEALGKVDIPWIRMHYAYPTGLTPKVITAIQDTPNILPYLDLPLQHSHPEILRAMNRPWQGQVNDDIIKRIKTAMPNAVLRTSFIVGFPGETEEHHSHLVEFVKRHEFDHVGVFTFSPEEGTPAYNLPNQLPQEVMDARRQEIMEVQQSISWQQNQKLVGQLVDVLIEQENPQTGELIGRSPRFSPEVDGLIYVKGEARLGCIVPVMITDADIYDLYGCLISSAA
>NC_008312|5699407:5783757|5726338_5727826_-|WP_011613119.1|DBSCAN-SWA
MDLSFASLGISEERANHLETIGFTEPTPIQAQAIPPLLEGKDIVGQAQTGTGKTAAFSLPILEQIDIDTNAVQALILTPTRELALQVTEAIRQFTGINSKGPTKRRLFVLTVYGGQSIERQSQRLQKGVHIVVGTPGRIIDMLNRNSLKLDHLKMMVLDEADEMLSMGFIQDVEKILEAAPAERQTAFFSATMDYSIRKLVNKYLQSPVTVKVAQQKTTPKRITQTVYILPRGWSKGKALQPILELEDPEAALIFVRTRQAAAELTNQLQSAGHSVDEYHGNLNQSQRERLLTRFRNQQVRWVVATDIAARGLDVDHLTHVINYDLPDSVDSYVHRIGRTGRAGREGTAISLIHPVDKRKLRLIERHLRQRLNTRSIPKRSQIEARQLQKLQDKVRSALSGERMASFLPLISQLGKEYDPHAIAAAALQIAYDETRPAWMGLDYSQEEDEPMYETPKPRLKKQLPKKSNNKSYSDKNKNLKDEIYVEEASLPQNN
>NC_008312|5699407:5783757|5749798_5750809_+|WP_011613131.1|DBSCAN-SWA
MLKTLFSWCKNFPVLKKISVFYSVTLVGFNFWVTPAIGDPFRKINPIEIGEKTEAAFEAMFEEGNYKEARDYLKIAECEEIGEPLIYAMISSLHYLDKNWDSLKLYAQKTTEVAENLIAIDPVRGNIYAATGYFLEGAYIISTEGTLKGAPKALEKLRKVLSHFESAERINSSDPELNLLKGYMDLMLAVNLPFSDISKAIEILENKAYPHHLAYRGLAVAHRDLDDFKKALQYVDKALSEVPENPEVHYLKAQILVAQAREKDNNLSLRKKAKKNFDKALAKSEQMPRRLVAQIFFEQCKNINNIDDRKRSCDSMRDIIRDGSGTWGPQELPALR
>NC_008312|5699407:5783757|5774036_5774372_-|WP_011613141.1|DBSCAN-SWA
MAGVNNPDTVQKMVDFAIEKFGAVDIAVSNISLEKRQNFLDISLKDWHEVIKTNLNSAFYLAKAIIPGMKARRWGRIIYISGYYGSIGTLYQAHNVTCKGGLNAFAKAIAT
>NC_008312|5699407:5783757|5747002_5747629_-|WP_011613129.1|DBSCAN-SWA
MEWHITDAQSLRIIDKEIGLHTLSPAEYEIVKRVIYATADFEYKSLVSFSEHALQSGAAALAARTTIVVDVPMLQVGITPVIQNTFVNPVYCSMDAITRPQKEKTTAAWGIETLARRYPEGIFVIGQAQTALCAIVDLIEADEIRPALVIGTPSGFVGVDVAKSRLYDSMIPHIRIDGRKGSAVVAVAIINGLVDLAWQAYGQKSPGN
>NC_008312|5699407:5783757|5702851_5703775_+|WP_011613103.1|protease|DBSCAN-SWA
MRNSIDAGRLYELFRSCIVRIKTSKSFGTGFWVTPGHILTCVHVIEGNDHDSIEIVWKQNNYQCTEINIFQDADLALLKVEIESHPCVFLDEDALPGDELYSYGYPEQKRDGASITMICEGPTDNKRFLTVKDENVRPGFSGAPLFNQRTFMVCGVLKSERKFPVNGNVLRALGGQAIPTARIFDKWPNLKISNQEFHQKYQSWRKELEVTKQQEQNSPQYSAQYSINSSSENPRIQSLKNQKQRIESQIAELEKLSHLCNQDIKAETNLAKRNQLHTQMDNYSTEINELYDKVQQIIAQINKFQNT
>NC_008312|5699407:5783757|5764285_5766127_+|WP_011613138.1|DBSCAN-SWA
MNNKKWRNAGLYALLAIVVIALATAFFDQQPQARETWKYSQFIQQVENKNVEKVDISADRTVARVKVADGSVVRVNLPNDPDLINILTQNNIDISVLPQNEEGFWVRALSSLFFPILLLVGLFFLLRRAQSGPGSQAMNFGKSKARVQMEPQTQVTFSDVAGIEQAKLELTEVVDFLKNADRFTAIGAKIPKGVLLVGPPGTGKTLLAKAVAGEAGVPFFSISGSEFVEMFVGVGASRVRDLFEQAKSSAPCIVFIDEIDAVGRQRGAGLGGGNDEREQTLNQLLTEMDGFEGNTGIIIIAATNRPDVLDAALLRPGRFDRQVVVDRPDYAGRLEILNVHARGKSLSKDVDLEKIARRTPGFTGADLSNLLNEGAILAARRNLTEISMDEVNDSIDRVLAGPEKKDRVMSEKRKELVAYHEAGHALVGALMPDYDPVQKISIIPRGRAGGLTWFTPSEDRMDSGLYSRAYLQNQMAVALGGRLAEEIVFGDEEVTTGASNDLQQVARVARQMVTRFGMSDRLGPVALGRQNGNMFLGRDIMSERDFSEETAAAIDDEVSNLVDQAYRRAKEVLVGNRHILDRLAEMLVDKETVDSDELQELLATNDVKMAALI
>NC_008312|5699407:5783757|5770498_5770714_+|WP_044136906.1|DBSCAN-SWA
MALKFAGFFNSKWGEPIPGKDNQAPVFVGVDTHSFKWGSPANSRTYPNELSFVIDPFSTQLKVQSRRFNLL
>NC_008312|5699407:5783757|5699407_5700592_+|WP_011613100.1|protease|DBSCAN-SWA
MKVKFLQKATSRILALGIGVSVNFTNFSVVNAQIRADKTIKIRYKNQIESIFVQSIEEQTNIRVYQQTNQAVVSIDTDKANGSGTIISRDGMVLTNAHVVSQGGIVKITLADGRKVEADVIGFGEKGLDLAVLKIRGETNLPTIRIASSGDIKVGQRAFAIGNPFGRFQGTLTVGIVSRIDEERGLIQTDAAINPGNSGGPLLNSAGELIGVNTAILTPSQLGGNIGIGFAISIDKVPELLKAVRERRAPLVAQHSRSRMFDEDFAKKLDFDALIEVQGNLDGESNVLPVDNSYYDLYAFKGRAGQKISIDMSSNQIDSYLILLNSEDQELAQDDDSGEDKNARIIIILPKDGTYKLLANSYEAGESGKYELKIEAISPKMRILFEQEKSNFYR
>NC_008312|5699407:5783757|5705711_5706707_+|WP_011613106.1|DBSCAN-SWA
MNYHFENNPKNRPSKPHSDSPKKVEPYIAPDELIDAVNLAIFLRRPLLLEGEAGCGKTRLPLAVAYELGLPFYRWNIRSTAKAQEGLYEYDAILRLHDVQTQKLEIKNNNQDKDKTYRNPSNPENYRTFGAIGNAFLSNCPAIVLIDEIDKADVDFPNDLLTVLDEPWEFKIRETGETITAKTNCQPIVIITSNKEKGNLPAPFLRRCIYYYLKFPDDPKQLQKIVDIHYQYKPDSEILKKINSSNNELVQQAAQLFIKIRENKGLFKIPGTSEFLDWLYALCSCQTKQNPQLPYPLEKLKEGELIPYRELIFKIRQDWQKNTTFPQTSDL
>NC_008312|5699407:5783757|5745007_5745214_+|WP_044136905.1|DBSCAN-SWA
MSAAYHFGDYLISLSVFPTEVKDLIASLGIKAGWSYLPIPYLEKGCNLKKDLLTFGGFDMRLDVFFQY
>NC_008312|5699407:5783757|5745693_5746383_+|WP_011613128.1|DBSCAN-SWA
MLVPLTRKTFEQLIPIVATGDQYKYYWGRLSEVLKRALISAVSVLVIVLINVLVHDDGDPLFLLVGITAGLYWFWGPVLLASFQNVELRRYPYSGLWQGKVFDVYLSEEVVGQEEKVNKKGELIIVENLEQRINLELQDKTGFKVEIQAPLRRYHQGISRGQIAVMLVMSYQQDLEKIAKYSDVYLPTVNLWVSNYPYLRKDVFVEVINQVRSSRRKNKQHQQPNFKFE
>NC_008312|5699407:5783757|5737923_5738106_+|WP_155994713.1|DBSCAN-SWA
MRVVNKYIACFKIYLLQIIHRDIKYKNIIRRSKNNKLLLVDFGYTKYPTTTAISKIGTAK
>NC_008312|5699407:5783757|5702510_5702855_+|WP_011613102.1|DBSCAN-SWA
MDNDLNIQVVPVELENGNVVRVEATVLNASGDTSDQEIESDVAANIRPLKEVTDTVKEIAATVKASIDQVKPTKASVEFGLEFGYESGKLTAMIVKGTAKANLKITLHWENISK
>NC_008312|5699407:5783757|5751286_5751739_+|WP_011613132.1|DBSCAN-SWA
MEVQFREFNPFDVWIWLEFSTVPSMAEKHYIEELFDSWFLLGKLGGFNAENLQVQEVGIEISYMEYSYNVASQSMMAVMHNMGDVEYEGLWGRCWFDLGTSDALAIDILVNSFQQLSKELVKIEKLIIGGQNEDWLVPENNYEKGWFDEN
>NC_008312|5699407:5783757|5748620_5749274_-|WP_011613130.1|DBSCAN-SWA
MLHLKNLYYHPAASLIPILENINMELAPKEMGLIIGRSGSGKTTLLEILAGLAKCSQGEIYWREQKLTSENLQQLGGLVFQFPERHFCGSTILEELRLGHPELRLEQISSALEEVGLQELPLSTSPQALSGGQQRRLALAVQLIRQPHLLMLDEPTAGLDWSIRKQLVNLLAKLKNHWSLLVVTHDSSDLLSIADKYWILNKGHLEEKSQDKLEIKS
>NC_008312|5699407:5783757|5740483_5740588_+|WP_155994715.1|DBSCAN-SWA
MILLFQTPYFPEFNPIERLWKDVKKIWKNRSFNS
>NC_008312|5699407:5783757|5771979_5772132_-|WP_155994482.1|DBSCAN-SWA
MIATVNELGGDAGLVLGIQLTRMLILLFVAPLLRNFIVKKEKPIDIVSEQ
>NC_008312|5699407:5783757|5732788_5733697_+|WP_011613121.1|DBSCAN-SWA
MSTEKQIDDQTDDQQVLGPIILTLFMGLMIICAWAFARPNAFKRPDIDVQLTENIDSENVNSQTEENQVTETLETETTKTTTIETKDAETTTTAKIIYKPSKVNIETTTSTKNPATDRTETTTSAQQPTANTNRIETRTSRDTEQPTTDKIETTTNTIESTAASQAKPETVSGQTDIVATSDSQEKYLTEAKTLGQIKFEINEVELSSPAKQTVNSLIPEINKYDPNRVTIKVEGHTSRVGDAQLNKEISQDRANVVVAYLKEKNLPHQVISEGMGYSQPLPNSNPASDINQRTVIILIPAN
>NC_008312|5699407:5783757|5743981_5744932_+|WP_011613127.1|DBSCAN-SWA
MTPTKLSDSEKLEIIELYQTTQENTITLADRYGVSSSTIRRILQSSIPEYEYKELVQQKQKRPSRSPRNIGHDTEENLDESVDGGNLELEESGYRANEVDGMVKRRRRRSSSSSDAETEELTELPKLSLTSEYTEKSNNAFEGSYDSPTKEIQEILAVDLREKPQNLDDFENDDLEDFDEEFDDEDKDKLEGEVEVEEVVDTSYNISIQNSSYSEVKVYNLTEAVLPKICYLVVDKFTELVTKPLIAFGELGQIPVEESQKKTLPVFNNHRVAHRFSARNQRVLKVPDGRMLQKTTVYLQAKGITRLLIDGQVYKL
>NC_008312|5699407:5783757|5736616_5736991_-|WP_011613123.1|transposase|DBSCAN-SWA
MNKTLEYIHNYPKEIKRIIGITYEQLTQLIENAIIKESENFQVIAEKEIRLIKPGGGRKKTLTKTDEIFLTLYYLHHIPSFQLLGINFGVSESTANNIFHYWINILPDLLPASLLEQVKKKKMN
>NC_008312|5699407:5783757|5766298_5766439_+|WP_155994481.1|transposase|DBSCAN-SWA
MQGAAFSQFLQILEYVAWKLGKKIIKVDPIGTSQNCWEYLNKVSKS
>NC_008312|5699407:5783757|5754716_5762189_-|WP_011613136.1|DBSCAN-SWA
MTQFQLTTPVVIIIFNRPDTTEKVFQRIRQVKPPQLLVIADAPRPDKPGEVEKCIAARKIVDLVDWKCEVLTNYAEVNLGCRERIYSGLNWAFSLVESAIILEDDCVPHLTFFRFCQELLDIYQDNNKVMAISGDNFQFGNNSIEYSYYFSRYPHCWGWATWRRAWKNYDNQMQLWPKLRDSKWLENILQNSHAVQYWSKIFQNNYQGFNSWAYAWIFASWNHHSLIILPKVNLVSNIGFGEEATHTLSINKFANMSTEEMIFPLNHPPSIIRNIEADEFTEKTMFSGSLQLQNVHCKVCGSISCKFDDAKVLNKYNVEYFQCSNCGFVQTENPYWLAEAYKEAIASSDVGLVSRNQNFSLITENLILNLFNTNSKFLDYGCGYGLFVRMMRDLGLDFYGYDKYCQNIFYQGWEGEINKQQKYEIITAFEVFEHFINPLAEIENILQHTRNILFSTKLLPPNNPHPNDWWYYALEEGQHISIYTTKALSVIGQKFKLNLYSDGESLHLLTEKSLSHSEFQNIFKVARYKPENRKKTLTQLDHEKVTEKKKKNQQQLDLKLLIDGVFFQINNTGIARVWKSLLEVWSKDSFAKNILVLDRAKTAPKIPGINYRSVPGYNYGKIDADRQMLQTICDEENADIFISTYYTTPILTPSVFMAYDMIPEVLAKNLNNPSWQEKHRSIRQAISYVAISENTARDLIKYFPQIPANYIRVAPCGIEAKFSRTTPQEVASFKSKYHINKPYFLIVGERIGWLGYKNTILFFQAFSKLKKSTEFDIVCIGGNRKLEPELSKYISGSKIHLLQLSDQELKSAYSAAIALVYPSKYEGFGLPILEAMACGCPVITCKNSSIPEVAGTAALYINDNDINSLVNALGEVQKSEVQQKLITAGLAQAQKFSWSQMAKIMSDVFIQTFNQIKAKRLSTMEDRKNLGEIQFKINHGQLEMQRHFWNVNSLDEAMFGRVLAYNGMDTLSPEEKKQAWEKSIENWVPQIMEGIPTKPEWKVLEIGCGVGRLIKYLRAKFARVDGVDISENMIQFARQYLADGKQNGEVYVNNGYDLQQLPDENYDFVFSTIVFQHIRSISIVKNYFREIFRVLKMGGYFRIQVHDYSAESLGKFDEEGAKDQQYYFSGNAYTEEQLKDLLIAAGFNLVSLKSAKPWIWATARREQQVEVGVEKIPQIVTLKNNQMGIEYPEINRLSYNKDRPFWSVMIPTYKKVKYLEQTLKSVLQQAPPPEEMQIEVVNDCPDYKIQAEIEAIVRKVGGERINCYRHFPQDIGQAPIFNICLQRAKGYWVHLLHDDDFVLPGFYEKLRRGIEKNTTLGAAFCRHYYIDENDHKKYLSVLERDTPGVIEKFIEKITVEQRIQVVGMVVKREVYEHLGGFCSQAASAADWEIWKRIAAFYPIWFEPEILACFRLHSSSETSRLMQSGGNIENARKAIEITQTYLPRNMAAELSNQAREHYGIEAMKMAASMLKIGNNNGAIAQMREGLKCSNSSSVINLLVSILINAETEAETSLIQATSQHLLSLEPQLIESKKTPHKVETNLLPSLAEINKEIELYKQNQLDKSALVKLQEIRKKIAYFWLSIDTLENLKIAYLGDFCQIHKALLTSSITDESLTETEKKIVTQIKANIVKGFKEPLDIKYLLAGMLYQRADQLEVKYEKAPIPKWFAIDYLNFMFASPQVFQEIGETDNYYHFMTGWLSYVHNNISINSESELWQAIARIFVENANWIPLYFTTRPNLKNLYIKRAEIIEFALKKLGLELNYTMPPYQFNRSKIRLGIIKDHYTPQTETYSLLPVFEHLDRSKFEIFLYAIKSNGHPLEQYCQSRADKFLQLPNELKNQVQTIRDDNLDILFFGSNITATIKNSTLLATHRLARVQVTSINSPTTTGMASIDYYISGKLTAPTEMTKEHYTEKLVNLEGSGLCFQDPIAETLPVVQPLRSSWGATNETTIFISGANFYKIIPEIRETWAKILRAVPNSILVLYPFNPNWTNSYPVGSFIQQMRGTLERHGIHSKRLVVIKPLPSKSDIKKCLELADIYLDSFPYGGATSLLDPLMLGLPPVVVEGNALRFRQGPALLREINIEDLIADGEESYINLAVKLATNSEWRQQKRQEIKEKMQQNPAFLDSRSYSAEIGKLFQELFQKWQNIHAPKTIESQDNNSLTSEFINRLVGCVNLYKIDPNDQSLIEELRQIRKQIANFWLDTNPQKLEIIYQGKVRQAYLSLLSSGIQNEPQTEKEEKFIKELTDISMGLTNSKSINALLGGMLYFLPGKMLVRDAKNRLPEWLINDYQQVFESREVVQKLEKDFQTKLPHFSEDSISRDLVSKPIKIAEVQTEKNIFLTENKADNLDFVISKFLNQLLGNVNLYYIDPSDESVVKELRQLRKQMADFWINLEPQKLENFYLGEMGKAYQALLNSEIQNQSLIESEQEFLQQLATQLSQGIEAPKAINYLLAAILYCRPEQLRIEDATKLPQWLLSDYQKFIGN
>NC_008312|5699407:5783757|5762329_5764039_-|WP_011613137.1|DBSCAN-SWA
MTNLNYLETSGWLKSLKEGKSIDYNSNPLPWYSYPAIEFIEDKLKSDFRVFEYGSGQSTLWYAQRVKEVISVEHNPDYFCQIKSYTPENVILSLLEDQEKYAAEINRYNDSYFDIIVIDGINRGRCAELCYRKLTANGLIIFDNSDREESDASLEFLQERKFKRLDFYGLLPTQKYKICTSIFWQDEELFNRASLPSKKNSCLGISLGQVEAINKRKNKNKASQDNQILACYEAIKNQPYFAEAYQRLGDMCYSQGQIEKSIRSYKKAIELQPDLAVVYAKLGKIYYQKSQLQEAIAYYQKVITLEPKSADIYWGISQILQQQGRLSEANIYRQKALETERDLTVKSFALNQLDLKLAPYLTWENGFFIEAGANDGISQSNTLYFEKYKNWQGILIEAIPELAEKCRVNRSKSVVENYALVPFDYGQDYIKLYYCNLMSFVDGAMKSEEEKKVHLKAGCQVQNINHSYEINVPATTLTAIIDKYGVENIDLFSLDVEGFELGVLQGIDFDKYQPKFMLIEVRLRDRKTIDSFLKPLYEPIAVLSDSINQTLPERSYQDILYKATNIKSR
>NC_008312|5699407:5783757|5782719_5783757_+|WP_011610772.1|transposase|DBSCAN-SWA
MNIIDKLNDFINQTKESKEIKRALAVKMTLSGKSYHEVKELLNVSHSFISEWKNQALFHGVESLRLQYQGRQGYLKTVEKEKTIEWLRAQDYLRLSDLKNYLQEQYDVVFESNQSYYNLFKEAGISWKKTQKKNPAKNDELVEVKRKEIQEFLAKWQPEIETGKLTVFMIDECHLLWGDILGYAWGKTDERIEIAIKNEKERQTYYGALDYKTKEFLVQEYESGNTKNTIEFIKYLQKQRPGNKLAIFWDGATYHNSQEFREYLMTINQYLSEEELLINCTRFAPNAPEQNPVEDIWLQTKNFSITFYHLCSSFKVVKWLFKFFADGQIFNFPKLFQYEILPQPT
>NC_008312|5699407:5783757|5715996_5716530_+|WP_011613114.1|DBSCAN-SWA
MRDYIVPQLPKAPLSRRALAFSIDAGIVWFLSAIISNNWFTFILFFVVFWIAIRVVMVYKNQGQSIGHFALDMKVLDSKYQRAPDILELSKREGILALAGSLAMLGMSNLTSGNAAVLLLIMPLFLDFTVALVDIERYQQAFHDRISHTIVVGTMRGYSLDIKLRWLLDEAKRYMIK
>NC_008312|5699407:5783757|5781862_5781979_+|WP_155994483.1|transposase|DBSCAN-SWA
MLINSIFYILYSSFHWRSLPQKLQPWQTVSTKFRKCHG
>NC_008312|5699407:5783757|5751772_5752204_+|WP_011613133.1|DBSCAN-SWA
MSKKNKIRVLALGLIRDGDRLFISQGYDSIKQETFYRVMGGGVDFGEYSRDALQREFKEEIEAELTNIKYLGCMENIFMFDGEERHELIQLYKCDFADFKFYQIEELTFWEKERKKKALWVSIDRFKSRELKIVPENFLEYCD
>NC_008312|5699407:5783757|5773772_5774021_-|WP_081432485.1|DBSCAN-SWA
MTAKRVSPGTIDTIRISKDYPNLDTKYEIMEKMIPVGRLASCQDIVETCLYIASDCSGFVNGQVINVNGGGLIITAHLDPII
>NC_008312|5699407:5783757|5714302_5715343_-|WP_011613113.1|DBSCAN-SWA
MKVNFNIVRQNQNTQPKIQSYTLEIEPGNTILECLNRIKWEQDGSLAFRKNCRNTICGSCAMRINGRSALACKENIRNELARLEKIATNNHHDYVTNTTVKSIPEITISPMGNMPVIKDLIVDMNSFWQNLEAVQPYVSTEARKIPEREFLQTPSERDKLNQTGNCILCGACYSECNAREVNPDFVGPHALGKAYRMIADSRDNQTTERLEKYNLDTAGVWGCTRCYYCNSVCPMEVSPMDQIGKIKQEVLARKDQQASRSIRHRKVLIDLVKNGGWIDERKFGIQVVGNYFRDLKGLYSLGPLGLRMLAKGKFPLIFEPSQGTETVRSLIESVKSLDNKFTGSKQ
>NC_008312|5699407:5783757|5706774_5707839_+|WP_011613107.1|DBSCAN-SWA
MFEPNSYLTTLFYHLRQAGFNLSIKEYFSVKDAIKGGWGTKNQEDLKKLLRLLWCNSWEQQQHLSLIFDRIFESEKTQETTPNPSTKNQKNLNYEQLESDSSTPISPTTKFQSSSTEITKPTTEKLSPLPITNIQPIREHENDAEFYTYYPISRRFMVYSWRYLRRPIADGLRDVLDIKMTVEQATKQGFFLQPVYRRREKNHAHLLIFVDQEGSMTPFHHFSQDLVETAKYESSIETVDVAYFHNLPAKYIYQDPFLTDKISLETVLNKCDSETRILIISDAGAARGYRQRTRVSGTTEVIWEIQQHTNLVAWLNPVPKMRWNNTTASIISHLIPMFPMDQEGLRQAILTLQR
>NC_008312|5699407:5783757|5740029_5740167_+|WP_155994714.1|DBSCAN-SWA
MYLSYRTVHQLVRYKLKSKLKVPHPNHIKQNKEAQENFKKNSHLN
>NC_008312|5699407:5783757|5707846_5709430_+|WP_011613108.1|DBSCAN-SWA
MTEITDKIIAQNKVEQFVSRFEDSYFLLASHVALPLVLTPELVNYLRIEFLKSEKVPWISEADLLLSNLCRPVGYELYVMDEGVRIYLLQKLAENPKFGQKRIKEIARLLLSYIKYLAKTNHFIGDKELQLQTWGAMLYLDTEKTVKEIAFAISQCIDKAELARLLKITQDFKQQIASSGQFQDFLDYAQLCNELLREPEKVTLEKITHSYQVAKLELTIPKIVLSKELDLGELFYFEVVKVDNFGNIIERSQESARQKIEYLGNEIKLEMVYIPGGTFTMGSPKSEVDSRDNERPQHQVTVPSFFMGKYPVTQGQWKAIASRTELKVERDLDPEPSYFKEPYESIDRWQRPVELVSWNQAVEFCQRLSKLTGRKYRLPSEAEWEYACRAGTSTPFYFGETITSELANYDGNHTYGKGPKGENREQTTPVGKFPPNAFGLYDMHGNVDEWCADDWYDNYVGAPTDGSARINSNKNSNTNSTKVFRGGSWIYYPWWCRSALRGNFNSDEADSISFGFRLVSFPPRTFE
>NC_008312|5699407:5783757|5733995_5734433_+|WP_011613122.1|DBSCAN-SWA
MTRKKPFSPEEFKLLYSQVPRLVVEVIVKTEIGVALTLRKDTAWNNLWHIPGGTVFYQEYIEDAIKRIAEEELSITVVKQKLLGYLEYPSEVKQRGFGWSVGLVFLCTTNSLLPSENQEGEKIQLFDYIPENIVEEHKNILNQLF
>NC_008312|5699407:5783757|5770703_5771591_+|WP_081432561.1|DBSCAN-SWA
MYFNGSVNTNTSVELVPLDIELELYDPIRRTESFEFDFDIVATTNTSNPQESADFVFPLNKVTDSSFKYKGKDYTIRILGFSQDKGRTFTREFRVLEDARTTAGLYAKIELDKGIGTSRADKLTGSNRDERLDGRGGNDQLIGRGGDDILIGGSGKDRLNGGSGNDKLNGGAGNDTLTGAAGVDTFVYDTGRNFRRRDIGVDKIVDFMLDEDTIVLSRTTFSKIESLAGSILQEFEVVDSNNAAIKSNAFIVYNQSNGNLYYNQNGSNNGFGSGGLFARLEGRPALEATDFFIDN
>NC_008312|5699407:5783757|5716568_5716757_+|WP_011613115.1|DBSCAN-SWA
MAKGVRIIITLECTECRTNPNKRSQGVSRYTSTKNRRNTTSRLELKKFCTHCNRHTVHKEIK
>NC_008312|5699407:5783757|5716919_5717138_+|WP_011613116.1|DBSCAN-SWA
MANYYRKRVSPIKPGDPIDYKDVELLKKYITERGKIMPRRITGLTSKQQRDLTKSIKRARLVALLPYVNKES
>NC_008312|5699407:5783757|5747935_5748073_+|WP_155994480.1|DBSCAN-SWA
MTSLILKSKANSLPAPGIIILDKIYQIFYEVASGDIFARRRKSAN

Homologous phage analysis in the prophage region

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_011613100.1|5699407_5700592_+|protease	trypsin-like serine protease	A0A1B1IT49	uncultured_Mediterranean_phage	4.7e-15	34.2
WP_011613101.1|5701247_5701946_+	peptidase	NA	NA	NA	NA
WP_011613102.1|5702510_5702855_+	hypothetical protein	NA	NA	NA	NA
WP_011613103.1|5702851_5703775_+|protease	serine protease	NA	NA	NA	NA
WP_011613105.1|5704607_5705693_+	hypothetical protein	NA	NA	NA	NA
WP_011613106.1|5705711_5706707_+	MoxR family ATPase	NA	NA	NA	NA
WP_011613107.1|5706774_5707839_+	hypothetical protein	NA	NA	NA	NA
WP_011613108.1|5707846_5709430_+	formylglycine-generating enzyme family protein	A0A7H6	Microcystis_virus	6.4e-92	64.0
WP_011613112.1|5712912_5713839_-	beta-N-acetylhexosaminidase	NA	NA	NA	NA
WP_011613113.1|5714302_5715343_-	succinate dehydrogenase/fumarate reductase iron-sulfur subunit	NA	NA	NA	NA
WP_011613114.1|5715996_5716530_+	RDD family protein	NA	NA	NA	NA
WP_011613115.1|5716568_5716757_+	50S ribosomal protein L33	NA	NA	NA	NA
WP_011613116.1|5716919_5717138_+	30S ribosomal protein S18	NA	NA	NA	NA
WP_011613117.1|5717511_5719536_+	VacB/RNase II family 3'-5' exoribonuclease	NA	NA	NA	NA
WP_011613118.1|5722163_5722937_-	1-(5-phosphoribosyl)-5-[(5- phosphoribosylamino)methylideneamino]imidazole-4- carboxamide isomerase	NA	NA	NA	NA
WP_011613119.1|5726338_5727826_-	DEAD/DEAH box helicase	A0A0N9Q9J4	Chrysochromulina_ericina_virus	1.4e-48	35.5
WP_155994479.1|5727948_5728101_+	hypothetical protein	NA	NA	NA	NA
WP_011613120.1|5730127_5731453_-	30S ribosomal protein S12 methylthiotransferase RimO	NA	NA	NA	NA
WP_011613121.1|5732788_5733697_+	OmpA family protein	NA	NA	NA	NA
WP_011613122.1|5733995_5734433_+	NUDIX hydrolase	NA	NA	NA	NA
WP_011613123.1|5736616_5736991_-|transposase	DDE transposase family protein	NA	NA	NA	NA
WP_155994713.1|5737923_5738106_+	hypothetical protein	NA	NA	NA	NA
WP_155994714.1|5740029_5740167_+	hypothetical protein	NA	NA	NA	NA
WP_155994715.1|5740483_5740588_+	hypothetical protein	NA	NA	NA	NA
WP_011613127.1|5743981_5744932_+	hypothetical protein	NA	NA	NA	NA
WP_044136905.1|5745007_5745214_+	hypothetical protein	NA	NA	NA	NA
WP_071820702.1|5745245_5745491_-	DUF1049 domain-containing protein	NA	NA	NA	NA
WP_011613128.1|5745693_5746383_+	hypothetical protein	NA	NA	NA	NA
WP_011613129.1|5747002_5747629_-	precorrin-8X methylmutase	NA	NA	NA	NA
WP_155994480.1|5747935_5748073_+	hypothetical protein	NA	NA	NA	NA
WP_011613130.1|5748620_5749274_-	ABC transporter ATP-binding protein	A0A285PWH2	Cedratvirus	1.2e-15	31.5
WP_011613131.1|5749798_5750809_+	tetratricopeptide repeat protein	NA	NA	NA	NA
WP_011613132.1|5751286_5751739_+	DUF3531 family protein	NA	NA	NA	NA
WP_011613133.1|5751772_5752204_+	NUDIX hydrolase	NA	NA	NA	NA
WP_011613134.1|5752207_5752822_+	tetratricopeptide repeat protein	NA	NA	NA	NA
WP_011613135.1|5752993_5753275_+	DUF3288 family protein	NA	NA	NA	NA
WP_011613136.1|5754716_5762189_-	methyltransferase domain-containing protein	NA	NA	NA	NA
WP_011613137.1|5762329_5764039_-	FkbM family methyltransferase	F2Y1T8	Organic_Lake_phycodnavirus	3.6e-24	41.9
WP_011613138.1|5764285_5766127_+	ATP-dependent metallopeptidase FtsH/Yme1/Tma family protein	M4QMW8	Micromonas_pusilla_virus	4.9e-136	46.1
WP_155994481.1|5766298_5766439_+|transposase	transposase	NA	NA	NA	NA
WP_044136906.1|5770498_5770714_+	hypothetical protein	NA	NA	NA	NA
WP_081432561.1|5770703_5771591_+	calcium-binding protein	NA	NA	NA	NA
WP_155994482.1|5771979_5772132_-	hypothetical protein	NA	NA	NA	NA
WP_011613140.1|5772258_5773647_-	2-isopropylmalate synthase	NA	NA	NA	NA
WP_081432485.1|5773772_5774021_-	SDR family oxidoreductase	NA	NA	NA	NA
WP_011613141.1|5774036_5774372_-	SDR family NAD(P)-dependent oxidoreductase	NA	NA	NA	NA
WP_044137774.1|5775406_5777062_-	hypothetical protein	NA	NA	NA	NA
WP_155994483.1|5781862_5781979_+|transposase	transposase	NA	NA	NA	NA
WP_011610772.1|5782719_5783757_+|transposase	IS630 family transposase	NA	NA	NA	NA

Sequences of DBSCAN-SWA_10

Nucleotide sequences of DBSCAN-SWA_10

>NC_008312|6564357:6616950|DBSCAN-SWA
GTTAATTTGACGCAATGCATCGCGCCTTTTTTTCTCCCAAGGCTGCTTCTAACATAGTTTGTAAGCGATGAACCCAATAATGTGCTTGACTACGGTCGATATCAAACAAGATACCAGCTAAGTCAAAAGTCGGGTAACATTTAAAGTAGAAGAGAATGTCAAACAATTTGTCTTGTAGAGTGCGTAAACGAGCCAAAAGACCTCCTCCAACAGAGCGTTGACGAGGTGAGCGAGTGCAATGTTTGCTCATACATTTGCCCAAAGGACTCCAAGAAAGATTCAAATGCTTTACGGTTTAATGGGTGTTAATGCTCTGAGTAATCTGTCTTGTTTTAAGGCTCGTTCAATATTTAGCATTTTTATGGCAAATTTTTTCTGAAATTATTTTACCTTATTTCCCAACAACTCTACTAATAAAGTAATAGAGTTATTGGGAAAACATGGCGATGTATTTGCTGCTTATGCTGATGCTATTGAATTTCTATCAACTAGAAAAGAGAAGATTCAAAAGGTTTACAGCTTCGATGTAGATATAGAAAGTCTTCAAGTAGAAGTAGTAGAAGTCTATCCAGACAGGGAAAAACATGATTGGAAAGGTCATCCAGTAACTGTCGGTTACGGTGACTTCTTAATTGGCCCAGAGACAACAGCTTGTTTGTACTTGGGTTATGTATATATGTTTAAAAAAAAATATCTGGAGGGTCAAGTATGATAGAAGATAACAATGCTGTAGTTTCAATTTCCAGTGATTTTAAAAAATTTTTAGAGATAACTAAAACCCACAACGACAACTTCTTCATAATGTTAGACTGCTCTCACAAATTTAAGTTTATAAAGGCAGTAGTTGAAGCGTTAGAACAATATGGAGATGTGTTTGCAGCTTATGTTAATACTATTAACCCTGGGCTTCCCCAAACCGAGAAAGAAGAGTTGGTCTACAACTTTTCAGAAGTAGCAAAGCGTCTTACTGTGAAAGCGGTGAAAGTCGACAAAGACTATCCAGACCACGACTGGAAGGATAGTAGTGTTGATGTTGTGTATGGAGATAGTAAAATATCAAATCATTTAGGCTACACATACATATTTACAGAAAACCCTGACGAAGCTACCGCAGAAAAAAGTGATGAGCCTAGTTTATTTTATTGATATGAAAAGTGAAAACTTCGCTTTAAACGATAGGGCAAATATGAAAGTAACCAAATCTTTTAGCCAGAAAAAGCTTATTGTAGTTGACAAAGTTAATGAGCAGTATATAGTTTCAGTTGTCTATTATAAAGACATTTCTGACAATCTTATTTCGGAGATGGAAAATAGGCTTACAATTTACGCTGACATATTCGCAGCATTTATAAATTCTCTGCCACTTGAAACTCCGTTTGAAGAGTACGAGAATATTACGTTTAACTTTAAAAGTGTTATACAAAAATATGATGTAAAGGCAGTACAAGTCGATACGAAGCATATCAAATCAGACTTAGGTTCAATATTTATAACGTATATAGCAGTGGGGAGAGTGTCTACTTTTGGAAACAACTGCTATGTGTTTCAGCCAATTCTACAGGAGCGTATGTGAGCGCTAAACTCTTGTAAATAAGCTTCGCTGGAACTAACGATGAGGTTAAAATCATCTCATTCACAGGATAATGGGTTTCCGCCTGTATAAGTTACAATGCTTATACAGGCACTACTTTACAGCACTTTTCAGGTAATTGAACCACAAAGTGCGGTAAAATGGGTTTGATGTAATTGTTAAATTTAATGCCAGTATCGTATTCGAGTGATTTGCGTCGTCGCGTGATTATAGCTTGGGAAGCAAAAGAAGGCTCTCAACGTCAGTTGGCTGAAAGATTTAAGGTCAGCTTGTCTATGGTACGAAATTTGTTGCGTCATTATCGTCACTCTTGGACAAATTGAGGCCAAACGACGTGGAGGATATCAGCAGCCAATAATTTCCTATGATAATCTCAACATCATCAAATCTCTGGTAGAGGAGAAAAATGACTTATTGCTGAGAGAATTATGCGCTCGCTATCAAGAAACAACAGGAATTAGGGTGAGTATCTCCACAATGCATCGCGCCGTAGAAAAATTAGGCTTACGGTGCAAAAAAAAAGTCTTTATGCCAGTGAGCAAGATACCCCAAGAGTCCAAGAGTTACAGCACTTTTCAGGTAATTGAACCACAAAGTGCGGTAAAATGGGTTTGATGTAATTGTTAAATTTAATGCCAGTATCGTATTCGAGTGATTTGCGTCGTCGCGTGATTATAGCTTGGGAAGCAAAAGAAGGCTCTCAACGTCAGTTGGCTGAAAGATTTAAGGTCAGCTTGTCTATGGTACGAAATTTGTTGCGTCATTATCGTCACTCTTGGACAAATTGAGGCCAAACGACGTGGAGGATATCAGCAGCCAATAATTTCCTATGATAATCTCAACATCATCAAATCTCTGGTAGAGGAGAAAAATGACTTATTGCTGAGAGAATTATGCGCTCGCTATCAAGAAACAACAGGAATTAGGGTGAGTATCTCCACAATGCATCGCGCCGTAGAAAAATTAGGCTTACGGTGCAAAAAAAAAGTCTTTATGCCAGTGAGCAAGATACCCCAAGAGTCCAAGAGTTAAGACATGACTATCGACGTTGGTTAGATAAAATTGATGTCAGAAATTTAGTATTTGTTGATGAAGCCCGAATAAATTTGTCAATGTCTCGTTTATTCGCCAGAGCCGTAGATGGGGAACGAGCTGTTGGTAGTAGTATCCCAGGTAGCAAGGGTGGAAATGTTTCTTTGATTGGTGCTTTGAACCTGGATGGACTGATTGCGTCGATGACTGTACCAGGAAGTACAAATACTGAGGTATTTATCACTTTATTAAACCCAGGTCTTACTACCTCAGTTGTGGCAAGGGGCAATCGTGGTAATGGATAATCTCAAGGTTCATCATGCTGAACGTGTCAGAGTTGCCATTGAGTCCGTCGGTGCTCAAGTCAAGTTTTTGCCCCCTTACTCTCCTGATTTATCACAAGTGTGAGCTTTGTTGGTCGAAACTGAAGCAATTTCTCCGTTCTTGTGAGGCACGTACCCATGAATCACTGGAGCAAGCAATGGCTGAAGTTGTAAATTTCATTACTGAAGATGATGCCTTCGGTTGGTTCAACCACTGTGGTCTATTTACCTGAAAATTGCTGTAAATATTGTGAGGCTAGATGGTGAAAACGATGCTGAAATAAAAAAACAGTTTAATATTGCAAGAGCAAACAACAAAGAACTGTTTTCAGTAGACGACTTTAACAATGGTGACATAAAAGCTTTACCAGCATCAACATACTAATCAAGCATGGGGCATCTAGCCCCTAATTAACCCAAGAAAACAACAGAAAAACTATGGGAATAATAGAACAAATATTAGAAGAGAGAAAAAGATTTCAGTATAAAATAGAGCACCTTTCCATAGAAACTCTAGCAGGCATATACCCTTTTTATGAGCTAAATCATAAGTGGCTTCCATCACAACAGTCAAAGTTTATTGAGTGGATTTTTCTTGGTTTGCCAGTAAATCCAATATATATTGTTTCAAGAGGCGGTCAGCTTGATGTAGGTTATTGCGCCGAAACAATTGACGGAGCAAAAAGAATCTCTGCTTTGAAGGCATTTGTTTGCGAAGATTTGGTTCTTAGTGGTTTGCACAGGTTAAAATGTTTAAATGGAGTTAGATTTAAAGATTTACCTGAAGAAGAACAAGAGCAGTTAACGAGCAAAGATATCAGAAGCAATTGACTGTTGTAGGAGCTCTAGCTACTGCCATTAAGCAAACTTTATCAGCTACAAAGCTTGCTGTAGAGGCGGGGGAACCTGAACTGGTAGAGAGTTTCTGGAAAGAAATGAAAGATATTCAGGAAGGTAACTATGACGAGAGAGAGAAGTTAGCTTTACCATCTAATAAAGGGAATAACAACGAAAACAACCCAGACGGTGGTCAAGGGCCTCACACTTATGAATCCCTAGTAAAGTTAACTCTGAAAGACATTAAAGAAATTGCTTTTAACCTTGATTTATCAGTCAAGCAAGCTAAGGAATATGGATCTGTTAGACAAAAGACTTCTTGGATAACAGCAATACTCAATAAGCAAGACGATCAACTTGCTGAGAGCAAGCCAATAGTAACTTCTCCACCACTAGAAAAAGGTGAAGATGAAATATTAGACGTTTCTTCTGTAACGCTAATAGAAGAATCAACTGATAACTCAATTAGTGAGACAGAGCCTAAACCAGTTAGCGAGACAGATACTAAACCAACTAGCAAACTAGAAACTGAACTAATTAATGAACCAATTAATGAACCAATTAATGAACCAATTAATAAACCAGAAACTGAGCTAGATGATTTTAACGACGAAGAAGAATATGCAGGATGGTAGAGGTATTATAATGAGTATATTTTTTTTTTTGACTTTAACGGAGTGTATTTGTAACAATATAAATAGTGAAATACTTGCTATAGAATTTATTGGACATTTTGATCCAACGAATTGCACACAAGAAAGCATATACAACGAAACCTCTACTTTAAACTCTATTAAGCCCTTTGACTCAAAAGTAGATCCAAGATTAGACGGCAGAGATACAAGAATTTCACCATATTACTACGAAACAGAAAGGAGTAATTTATTTTGAAAAAAGCACCAAGCTTAGCAGCGTCAAACACAATTACTATTGTTAAACCAAAAACAAACACAACACTTATATGGACCATAACCATAATGTTGTTATCAATAGTAACAATACCAGGTGTTTGGCAGTTTTCTTTTGACTTGTTTCAAAGCATAACCAAAAGTGTAGCTGATTAAGAAGTATCTGTGGCAAACTCCGTTAAAAGTTATAAAGCAAAAGGAGTTTGCGTCTACATGAGACAAGAAAATCCAGTAATATTAGGAAAAGTATTCAATCCTGATGAGCTTTGGCAGAAAATAGGAACTGTCAACCTAAATAGAGAATGCTTTTCCAAACATATTACAACAATTTACAACATCAACAACTGTGACTCAAGGCTTAGAAATTTCATAAGCAGATGTTTAATATCTTGGAAAAAAATAATAGTAGAAAAGTCTTTTGGCCAATCAAGCAGATTTAGCTTTGTAGCGCCACATCAAAAGATAATAATTTCCAATGTTGAAACAATAATTAGCTTAGAAAATAGAAAGTTTTTAGTCAAACCAAATGTAATAATCTCATGTTTTTCTACTAGTTGGGACATAGATAATTACAGAGATATTATTAGAACAACAATAACAGGCTTCAGATGAGATTTGATAATGAAGAAGACCGTAAGAACCAGAAACTTCAGATAAGCATTCTAGGATTCTACGACGAAGAAATAAGACTAATTAAAACTGAAGAGTCATCAGTAATAGTTACTAATTCTAAGGAAACATTACAGTCTAAAATAAAAGCTATTAATGCAGTTACACCTGTAATGAAGAATATTAATAATTCTAGTTACTACTACACTATTACTGTACTAAGAATTGACAATTTAAACGTCGAGTTCTATAACATAGATTCATACTATGAAGTAACAATGGCAAAAATAAACGAAACGCTAGACATAATAAAACGAGTGTTATACTCAGAAATTTCAACGTCAATAGTAAGGTATCCATCAGGAAACGTAATATTTTCTTCTGATACTTGCTTAAACAATGACGGAAGTTATACCATAACAGGATTTGACTACACTAACACAAGCGCTGAAAAATATTACGCTGTTGGTGAGTACGATAAAATGCTGAGATACCTTTTTAAAGATAAATTCCTTCGTGAATACAAGGTGTTAGGTTATCTTTCGAGAGAACTTTTGGATCCTAACAGGACTAAGCCCTTAAAGGAAGTCGAAGTCTACATAAATAGCAAAATAATTACATTCGGTGGTTTCCCCGCAGCTATAGAGGAATATTCTATTGCAGCATAAATCCTAATTCAACTAAATAATTGAACAACAGAAAGCTTGTACCGATTTTGGCACAAGCTTTTTGTCGTAAAGCAACTACTAACAATGTATCAATTAGCAGAGAAAAAAGCAACTATGATTACCGATGAAGAAGTATTTGAAAGCATAAACAAAGATTTCAAGCAGAACACAGGTTTCTTTGTGTCTGTTATAAAGTGTGGTACTGAATACCTGAGAAGTGTAGATTACGAGAACTCAAAGCTAAAAAACCGCTTAGAGTTTCCTACAAATCTTGTAAAAATAAGGGTAATAGATTCTCCCATAAATATAATAGAAAGTAACCAATTAGCGAACGCGCTAAACATTTTTTACTTTGAAATAGACTACCAGACAAACAGGTATTCGTGGGAGGAAAACAGGGAACGTTCTACAGAAAATTTTGTAAAGCTTTTTGAGAAAATAGATAAACACCTATTTGATACGATAGTAAAGAAAAGAGCGAACGTAGCCTTTCTAATGTCTCACAAAGTAGCTAAGATATCCTTTAAAACAAGGTTTTTCGGGCTTATAACTCGTTTATGACCTACGAGTTTAAGATGTCAGAGTTTGACCCTGAGATTGACTTAAAATACATAGGTTATTTAGCTTTAGCCTACGACAAAAAGGAAGGAAAACCTGTCTCCTCCCCAAACGACATTCTAGTAATAGAGCAGGAAATTAGGGATGTCTCAAGACGCATAAACTATAGAAACACAGAAATCCCCATAGAAAACCTTGTATCAAACATAATCCCGGGCTTCACATCAGAGTGGGGTATCGAGAAAAAGTCAAGGGTAATTGAAGATGTGTTACTTGGAGTACCTATTAACCCAATATGGGTTGTATCTCTTGACACATACGATGAGGATCGGTTTATAAAGATTATTACTGGAGAAGAAGTCGTAATGGCATTGAGCGATTTTATTTGTAATAAGTTTTCTTTGTTTGGAATGAAACTAATACAAAGCTCAAAAGGTGTAAAATATCAAGATTTCTCAGTGCAAATGCAGAGGAAAATTACCAGGTCAACTGTCAGGCTTTTAGAACTAAACCCACGAGTCGAAGGCAAAATCCTGGCATACTTACGCAAGTCAAACGCCTATGGAGTAAATAATGCCTGTTGAACTAACAAAGCCTTGGAACATAGACGAAATACACTACTGTTGGATAGAATGGCTAATTGAAACGCCTTACACAGAACCAGCAGTAGACTTTGACAACGATGAGAAGTCTAGAGTTATTGAAAAAATTTTCCTTGGAATTCCCATCGGTCCAATAACCGTAGCACCATTCTCAACAAAGGATTGTAACAAAATAATAGTTGACGGCGCAAAAAGAGTAAAAGCTATAAAAGACTTTTGTGCTAACAATCTAAAAATGTCTGGACTTCAGGCCTTGTTTAGCCTAAACGGCGCTACTTACCTTGACTTATCAGAGGAACAAAGGTTTGAGTTTAAATGTTCTATTATTCACATAGTAAAGCTTGAAGAACATGATGAAGACGCCATAAACTACGTTTGTTCTAGTAACCCAGGCAATAGCCACTGGCTAAAACATGGTGCTCCGCATGAATAGGTAGTGCTTTAGGTAAAACAATGACTGAAGAATTAATCAACCTAACATGGAAAAGTGTAAGTGATATTAACAACCCAGACAATCCAAAAAGGAGAGGTTGGTTAATACCATTGGATGACTTGGATGAAATAAAGCGAGGAACTTACTGTAACAAAACAGTAGTACTAAAGCTGGATAACTTAAACCCTCAACAGATAGTTTTAAGCGACTACATGGAGAGTAAGGACAGGGTAAAACTAAGAGAGACCCAGGAGCTAACTCATTGGGGAAAAGAGTACAAACTACGCCCTATAATTTACAGAAAGCCGAAAAACTATTTCCCTAAAACAGAGCATGAGTTACCAGCAGATTTTTTATCAGCAAGAGGAGTAATAAAACGTGGAGAAGTTTATGTAGCTTTTATTTACCAAACGTCAATTAAAAGAATATCAACAATGAATTTGTTTACTGTTTTAGAATGATAGTATGCGATGCTTCCCATGAATAGGCGATATCTATTTATTTAAAAATGGCAATGTAATGTAACAAATGTATAGCATTGCCATTAAAATCATTGATTCTAATCATCCTGTATATTTTATCAGGAAAGCTTTTTGAGAATTTTGCATTACTATTCTGAGCACCCATGTTTTTATGAAAACTGAACCAATTAAATGCAATGTTATTGGCCTTTACAATAAGGGAATAGCATTGCTTTTTTCAAAACAAGATTATGACAATTTGTTTGAGGGCGATCGCCTAGACGAAGCCTTAAATAAAGGTCTTAGCCTGGAAATAGACAACGACGTAACAGGCGCGAGAATAAATGGATATGAAGCCACTGAGAAAATAGCAATCAACGAGCACTTAAGGTGGCTTGACGTAGCAAATTCAGAGTATAAGATTCTTTGCAACGTTTCGCAACAAGTGGGTAACATTAAATTGCTAGGCAAATGTAAACTTGACTGCAACGTTGAAATGAGACTTCCAAAGGAAATGCTTATTTGCGTTTACTACAGCATACTTGAGTGTGAAATGTTTGAGGGGTAATTTTTATGAACACTGAACCAATTAAATGTAATGTATTAACTGAAGATGACCTTGACCCACAAGCTGGGTTTGTATTTTCAGTTGAAGAATACAACAAAGTTTTTAACGTAACCTTTGACTGTAAGAAGGTTACTTTAGAAGTAGACGGAGCGATCAGAAATGCAACATTAGAATCTTACAAGCTTGTGAATGAAACGGAAGTTTTCACCCATAGGCGTGAGCTATTTATTTCTAATTCAAAAGAGCCAGCGACACACGTAGTTGAATTGTACGAAGGCGCAATATATCGTGTGGGTAGTTGCATGTTCAGTTGCGAGGAAATTTTAATTGAGCCAGAGCCAATAAACATCTATATATACTACACAGATGAAGAGCTTTACAATAAAAGAAAAAGCAATGAATAATAAGGTATATCAGTGCAACATAATTATTGAGCATGAAAGGTCTTGGGAATGGTTTCAGCGAAACGAGAATCCTAATGGGAAGATATCTTATGAAGCTGGGTGGGCTTTCTTAATAGACGATTACAGGGAAGTGTTTGATGACAATTTTTCAAAAACTATTCTTGTATCTTTAAGTGGAGAAAGCCCTAACAAAACAAAAATCAGCAACTACGTGGAAGGAAGGAAAAGAATAGTCACTTATCACACACAGCACTTACGAGTTTGCGGATATGAAGACAAGGTTAACTCTATAGTCTGTTTTCAAGAAGGAAATCTTGAAATGGTAGGCACATTTGAGTTTAAGTTTTGCAATGAAAGTAGCGATTGGAAAAAAATAAACCTTTACGTATACATACCAGAATACTACGATAAAAATGTCTAATGAAATGAAAACCTACGAACTAAGTGTAGATAGTAGCATGGGCTGGTACATAAAAAACCAGGTAAAGTGGATGAAAGTCTCTGACTTAACTCCCGATGACTACGAAGAGCTAAATTCAAACTCAAGGTTATTCTTAATAGCTTACAAAGAAAGAATATTCAAGTTAACTTATACTTTAGTTCAAGAATTTTTCAAAATAGAAAAGTTTGACGACGGAACTCTTTATCTGTGGAGTTTAAGTGGTTATAAGTTTAATAAGGAACACAGAACTGCATATATAACCGCTTTAGAGATAGAGGATTGGAGAGTTGAGGACATCATAAGCTCCTATAGCTAATTATCACCCCCATCGTAGCCAACTACTTTGGGGATTAAACAGTAACAATGCCATGAAACAAATAATTGTTAAGCTTTTTCCAAGTAAAGTCCATTTTCTAGATAGTGCAGACTGTCTATAAGTACCACAAGATGATGAAAAAAGACTAAACGAAACTGCAACCCATATAGGGAGAAATGTTTTGGTCATTAATGCTGTAAAAATATAACAAAGCTATAAATAAAAACAATGCAAGACTGGAAAACAAACTTGTTAAACAAAATAGTAGAGAAATACGTAAATAACTCTAATGAGTGGGTGGAGTTAGAGTTTGATTTAAACAAAGTTTTAGAGTTAATAATAGTTTCTAACAATTTTTACGGCAAAAGTAGCCAGGAAAGGGGAATTTCTGTATCTAAATATTTAAAGACTATAGGTGCAGATGAAATTAGCAAGTATTCAACGTATTATACTGTCGAAGAGTCTTACTCAATAAACCTACGCAAGCCAAGCAGGTTAAAATATTTTAACCCAAGTACTTGGCTTGAGCTGGCTTACTGTGCTGCAAACCCTCAGAACTATACAAAGGTAGAGCGAGTTAAGCGATCGCCGTCACCTAAAGTAATAGTGTTTTATTCTTACAGGGATTCAGGAGATAAAACCACAAGTGTAGCAATTACAGGCTTAAAACTGGTTGAAAAAGGCTATAACGTTGCACTGATGGATTTAAACCTAGAATCTCCAGGTCTAAGTGCCTTGATTAACCAAAAAGAATTGCCGAAAAAGGGTTTTGTAGATTATTTCTACGACAAATCTTTTGGGAAAGTTGATGTCGAAGTTTCAATAGACCAAACATTTTTTGAAGTAAAAACTAAATTTGAATGGGCAGGCGGCAACCTGTTTGGCTTTTACCCAGGAGAATTATCGCCAGACTACACGTGTAAGTTAGAATACATTAACCCGCAAGTGGTTCTAGACGACAATGAAACACTCTGGTCTGTTCTAAAAAAGGAGGTATATGAACATTTAGACTTAGACTTTATACTAATAGATTCTGCTAGCGGTTTGAGTAAGTGGGCAGCGTTGTTACTAACACAGGCAGCAGACGAGGCATTAATTTTTACTGATACCAGTGATAATAGCATTAATGGAACTAATTTAATATTAGAGGCCATTGATGTACTAGGCTTAAAGAAAAAAATAGTCCTTTCCCTTTTAGAGTTTGTCAACAAAGACAAGGCGATAGAAAATGCCTGGGAAAAAATTAATTTCAGTGTAAAAAGAGAGGATGAATTTTTTGTAGTTCCGCATTTTTCCTTAAACAATTATACAAATATAAACCAAATATATTCTAATATAGCAAGATTCATATATTCAAACTAAAAATGATTTTATTTTACAAAAAATTGGGTATTTATTATTATGAAAAAACTTGAATTATTTTAATTTAAAATCTATGACAGTCCTAACCTCCATGACAGACTACCCACTAAAATATGACAAACCCTCTAAAAAGTCTGTCATCCTATAGCAGTATAAGCTTGAGGGTGTTTTATGACGCGATGACAGACCTATAACCAAGTTAGTTCAGTTTTATATTTTCTCTAAAATATTCAAATATTTTTAACTCAGCGTTTTTTTTTGAGAGAAATCCTAATTTTTTTTCTAAATGCCTTAAACACCTGTAAATATAAGAAATATAGGTTAAAAAATAGTGTTTCAATTTTTTTTCCATCGGGAGTTAGGATATAGCGCGTCATCGCGTCATAAAACCACCTCAAATCTATATTAATCTAGGATGACAGACTTGTTAGTAGGCTTGTCATATTTTAGGCAAAGTATGTCATATTTAGTTAGGCTTGTCATAGATCATTTACTTGTGATAGTTCTCAGAGAGAAAAAGCCTATCTTTTCATAAATAGATAGCTTAAAATAAAAAAAATGATAGCAAAAAATATGTTGACTTTTTGCTTATTTGTAATATAATATAGTTATTAAGGTTAAATTCTACGGACGTATTTATGCTTTATTTTTAACTGGTTCTAACTCTTACTTTTTTACTAGCTATTGATTTCTTATTAACTTTTATCATCCATTAAATAATCGACAAGTGGCTTTGATTTTTTCTGAGCTACTTTTCTATATTTATACTACAATTATAAATAGTAGTAATAATAGAAATATAAGTCTAATGCCAATATCTTGGGAGTCTAATCTTACATACTTAAAGCTCGGTAAAAACCTTATACCCTTAACTAAAGACGACAACGAGCCAGCCAAAGTGTATATAAGTTTTAGAGGCACTACGGTCACGTCAAAACCAAAATATCCTGACAGAGCAATAAGAGCTAAAGAAAAAGATGGAGGTGATTTTTACAACTCATCTACTACTTCCTAAAAATTTGTAATCATAGGAAGAACTTAGTTGCCAAGTTTCATCACCAACTACTTCTAAAACTTGTTGATGATATTCCAACAAAGTTAGGTGGAGTCTTACACTAATATAAGTTATAAGTAGTTGATACACATTACAAATGTTTGTAGATATTTTGTTCATTTTTCACATCCGGAGCGCTAATGGTGCTTTATCTAAAATTGCATGAGGAGGTTGAGTCAGCAACAAACGTGCAAGAGCAACCTGCTGTTGTTATCCCATGAAAAAACATGCTCCCGATCTTCGATCGCGCCTAAACCACTAAATCTTTTAGTTAAGTCTAGTAGGTCAACTTTTGTAAATCTTTAAAACAAAAGACCCCAGCTATTATATTTGGGAATTTGAGCAAGTATCAGATGTAGTATTAGAAATAGTCTCCTTAGTTGGGTAGTAAATTTGAAAATTATGTGGAAATGGGAGTAGAGTACTATGCAGTGTTGGAAGCGTTGCAAATGTTAGGTGAATATTTTCACTTGAGTCTATAAGTTGGAAGCGAGTGGTGATCAGCAAATGGCCGAAACTTGGTTAGAAAAACTCTGGTTGGGGTTGACTTTATGATCAGGAAAATTTGAGGGTAAGCAAGATATTTGGTTGTGTTGGTGCGATATTGAGGTGAATGTCATGCTGGTGCCGAAGGTGCGAACCAAGAGAAATTTAAAAAAGAGCTGGCTTGACAATGTGCTGAATGGGAAAAGCTGCAAAAGGAGTCTACTTTAACTGAAGTTAGCAGAACTTGAGGCGAGGTTGCGTGATTTTGGTATGGTAGGTAAATATTTATTTTACAGATACTTGTGGTATATTTAATAGTATTTGACTACAATCAATTTTTGTAAATATTTTGTCGTTAAGTAATTTTATTGCTGAATATGATATCTAAAATGAAAATAGATAAAACAATAAAAACACCTGCTCTTGATATTACTCATTTAATTATAGAGGATGAAATTCCAGTAGATAATTTTTAATCTGATCAACTGCAGGAATTTAGCTTTGGCTGATCAATATAAGTTTCATAATTTTTGTGAAACTTGATTTATAAGTGGGTAAAAATTACCGTCAAAATATTAAAGAACTAAGAATAGCAAAATTATTGATAAACAATGGAAAAAAAATCAAAACGCGATCGCGGAAGAATTATCACAACTTCTGGACTGAAAAAATTAAATGAAGCTATTGAAGAGTGGAAACAGAAATACAACCTTAGAGGTACTCTGGCAGAAATTGAGGCAGAGTCAGGAGTTGGTTCAGATACTATTAGTAAAATTCGACAAGGACGAGTAGGTGCAGACCTCAGCAAAATTCAACAACTTTTTGCTGCTTTTGATCTAACTTTGGATGAAACTGACTACCGCTCCGGAAAACAAAGCTCATCTGAAATGGACTCAGAACCACTATCACAACTACTACCACTTTTAAACGACGAACAAATAGTCACTAAAAATAGTTTCCAAATTTTCATCAGTTATAACAGGCAAGACCCGGATCAAGAATTGGCGCGACAGTTTGAAACAGCCCTCGCTGCTGCTGGTCATCAAGTATTTATGGCAGGAGACCATATTCGTCTGGGAGAAAATTGGTTTCGTCGAATTAATATTGAATTGAAACGCTGTGACTATTTGTTGTTATTTTTGCCTCCTCAGTCAGCACAAAGTGAGTTGCTCACCTATCAAGTGCAACTTGCCAGAGAATTACAATTTTCCCGACCAGAGCGTAAACCTGTAATTTTGCCAATTCGGGTAGGTTTTTCTCTGACTCAACCTCTCAACCATGACTTACGTGGTTATCTGTATCGCATTCAACAACGGGAGTGGCGATCGCCGGAAGATACAATTATTATTCTTAAAGAAGTTTTGACTCTTCTAGCTGCTCCACCAGGTAATATTGCCCTGGAAATAGAGGAGAAAAAAGAAATTTCTCTGAGTGAAGAAATTAGCAGTATCGCCTCTGCCAACTTCCCCCCTTTACCCTCTGCAGAACCAGAAATACCAGGGGGACAAATTGATGTAGCATCTAATTTTTATATTGAGCGTCCTCCCATAGAAGAACGTTGTTATCAAACTATCTTACAACCGAGTAGTTTGATTAGAATTAAAGCACCTCGACAGATGGGAAAAACTTCTTTAATGGCAAGAATTTTACATCATGCTGCATTCCAAGGATATCGAACAATACCTTTGAGTTTTCAGTTAGTAGATAAAGAAGTTTTTAGTAATCTTGAAAAGTTCTTAAAATGGTTTTGTGCTTATGTGGGAAGGGAGTTACGTTTGCCAAATCAATTAGATGATTATTGGGATGATATTTTTGGTAGTAAAGTTAATTGTAAGGATTATTTTGAGAAATATTTATTAGCACAAATAGATCATCCTTTAGTCTTAGGTTTAGATGAAATTGACCGAGTTTTTCAATACCCTGATATTGCCGAAGATTTTTTAGGATTATTACGAGCCTGGCATGAAGAGTCAAAACGACGTGCTATTTGGAAAAAGTTGCGCTTATTAGTAGTTCATTCTACTGAGGTTTATATTCCTATGAATATTAATCAATCTCCTTTTAATGTGGGGTTGCCTATAGATTTACCAGAATTTAATCTCCCGCAAGTTAAGGACTTGGCATTCCGACATAATTTGAATTGGTCAGAGCAAGAAGTAGAGAAACTAATGGCAATTATTGGTGGGCATCCTTATTTAGTTAGGGTGGCATTATATCACATTTCTAAACAAGATTTGACTCTAGAAGATTTACCGGAAAATGTAATGAGTGAAACTGGAATTTATAGCGACCATTTGCGACGACATTTGTGGAATTTAGAAGAATATCCAGAGTTAGTTGCAGCAATGAAAAATATAATTTCTGAAAATTTGAACGAACGTTTAACAGGGATATTAGGTTTTAAGTTAGACAGTTTGGGTTTAGTAAAATGGCAGGGCAATAAATACCATCCCAGATGTGAGTTATATCGTCAATATTTTCAGGTTCATTTATGAGGTTAGTCTAGTAATTTTAGCAATTTTTGCAGTTTGGTGTAAAATAATAAAAGTTTTTGTTTGTAGTAGGGCTTTAGCTCTATATATCTGAGGGGAAATTTCGTAACTTATAAAGTATGAATAATAAATCAGAAAAAAGCTTTTTTTACGATATTTAATTATAACTATTCAACCGGAAATAATACTATATATTTTTTCAAAAAATTATGTATACAGAAACAAAAAACTCAAATAAAAATGCAGTCATTGTCGGTGGAGGCCCGGCAGGTTTTGCCACAGCATTAATATTAGCTAAACGTGGTTGGCATCAAATTACAGTATTAGAAAAACGACCAGCTGCAGATTTTTATGAACCTGATAAATCATTTAATTATTTAATTGATGGGCGGGGTCAAAAATTTACCGACCTATTTAGTTTAACTGAAAAGTTAGCAAAAATCAGCGTACCAAATACAGAATTTTATCTTACAGAAATTAAGGCTAATGGTAATCGTAAAACATCAAAATTACCAATCATAGATCCTAATCGCAAAACTGCTTATTGGCTACAACGTCCAATATTTTTGCAGCTACTTTTTCAAGAAATTGAGGAAAATTGGCACAATAAGATTACAACTTTATTTAATACAAAATGTTTGGATATTAACAAGAAAGATGGAAAATTAACAATCATTGCTCAAGAAATAAATGACCAAAATAACTATGAATTTGAAGCAGATTTATTAGTTGGTTGTGATGGGATTAATTCTCTAGTTAGACAAACTTTAGATAAGTGGGATAATTCTGGAACAGATAAATTTAAAATGCAGTTTTTTCCCTCTGCAAGTTCTGGTTTGAAGTACAAAGTTTTGACGTTACCCCCTAACTTCCCTCTAGACCATAATAATTCTGAACAAGCAGTTTGTACAATGGCTTATGCTATTCGTGGAGCATTTTCAGATTCTCAACATTCTTTATCTCTAGGTATTTTGCCTTTTGCTGACCCTAATAAACCGAGAACAGCAAATATTATTAGACGACCAGAACATGAAATTTGGAAATTACAAGATGGTGAAAAATTGTCTGAGTTTTTCCATAAAGCTTTTCCACAATTGCCAATAAACGAAATAGTTTTATCAGAAGAAAAAGAGCGTTTTGCTAAAAGTGAGGGTGGATATTTCCCCATCCCTCAATATTGTTCTGGGTTGCATTTTTTATTATCAAATACAGATAATTCTAGTGGGGTAGTTTTATTAGGAGATGCGGTTCATTGTTTTCCTCCTGATATTGGGCAAGGTGTTAATTCGGCATTGGAAGATGTTTTTATACTTAATCAAGCACTTACTAAAACTAATGATATTATCTCTGATACTTTGCCATTATTTGAGTCTTTACGTTCTCCAGATATAAAGCCTTTAATACGTCTAGCTCAAACTGCTTATCCGTGGCAATATAATCAAGGTATTCTCGGTAAACGACTATGGAGTATTAACTTTTTTATGCGGTTCTTATTGAGTAAAATATTGCCTTTTATTTTTGCTCCTCCCGCTTTTATATTAATTCAAAATCATCAACTTAGTTATCGTGAAATATGGAGAATGGCTCAAAGAACAACTCTCTTTATATTTGTCTTGGGAATAGTTATTGTTTTAGGAACTATAGCTTTATTTTTAGAGAATTTATAGTATTTTTATAATCAGATGCAAAGCACTTTTTGAATTAGGGTTAATTATTACCTCTATAACACTAATTTTTTTTGCTAGGACAATAAAAATTTGGTTATAAGATAACAGAAAAAAGGAGTAGCTAGACAATAATAAAAATTAGTAAAACAGACAAGGTCATAGTTTAAGTATTCAGCACTTTAGCAGTCAGCTTTCAGGTTTTGAATTTATGCAAATAACTCTAAGGTTACCTGATGAGCAATTATATAATAAATATTCCTAATATAAAGAATAGGGAGCAACAGTCATATTATGCAAACATAACTTTTTAATTATACTTGGAGACTAATTCCTCTTTCCAATATAATGAGTTAATAACTCATAGCTGATAGTTGAATGCTGAGGGCTGAATGCTTACGTTACAGTTATAGTTACAAGTCATTTCTACGATGGATTCAAAAGTATTTATTATTACAATATAATCAATTTATCACTAATTTATTAGAAAAATATGGGTTCTTAAATGTTTAAATTTTTACTCCATTTTTATCTGGAATAAATCGATAATGTGATTTTTAAAATTTTGGATTTACCGAAAAAGTATCTACTTTATTAATACCTAACCTAAATTATATTTTTAGCTGAAATTCTAGCAATTGGTTAAATAATCAAAACATCAAAATTATCATATAAAACTTATCTATATTATGTTTAAAAGTCTAATAATTAAAAATTTCCGATGTTTTCAAGAAATTACTATTGATAATATAGAACGAATTAATTTAATTGGAGGTGTTAATAATGTTGGTAAAACAGCTCTCCTGGAAGCAATTTTATTATTAAATAGTTTAAATTCTATAGAAATTCCGTTTGAATTAAACTTTAATAGGGGAGTAATTCAACAACCAACTTTTGACATTGAAGAAATTTGTGAATGGTTATTTTATCAAAAACAAATTGGTAAATCTATTAAAATTCAAACCATAGATGAAAATGGTGAAGAGAGAGAGTTGAAATTGAGTTTAGATAAAGCATTAAGTCCAAGATTATTTCCTTTAAGTTCAAAAACAAATAGCAGAAAAACTATCAAAGACTTAAAACTGGAGCTGAAAAAAGCAGGTCAAAAATTATTGGGTTTTACAGCATTTATAACCATAGATAAAGAAGGAGAAATTAGGATAGAATTTCAGCAAGATGAAAAACAAAAAATTGAAGAAATACAACTTTTTTATCCTATTGTTTTTCATAGTAGTCGTTTAAAAGTTTCTTCAACAGAAAATGCAAAAGTGTTTAGTGATTTTGCACTAAAAAATGAACAAAATGAAATTGTAGAGATATTACAAATAGTAGAGCCAAGATTAAAACGTTTAGAAATTTTAGTCACTGGAGGAATACCTATTATTCATGGAGATGTTGGAGGAGATAATTTAATTCCTGTTGTATTAATGGGAGAAGGAATGGGAAGGCTATTATCTATGATTTTATCTATCATGAATACTCGAGGAGGAATAGTATTAATTGATGAAATTGAAAATGGCATACATTATTCAGCTATGGAAAAAGTTTGGCAGTCTATTAATATAGCAACTAGAAAGTTTAATACTCAACTTTTTGCGACTACTCATAGTTATGAATGTATTCATGCTGCTCATCGAGCATTTTCCGACTCTGAATCATATAATTTTCGTTATTTTAGACTAGAGAGAGAAAAAGAAACTAATTCTATTAAGAGTTTAGTTTATGACAAGGATAATATTGAAACTTCTTTAGGACTTAGCTGGGAGATGCGCTAAATGACTCATAATAAAAAAATTGAAAAGCCAAAGCTTATTATTGGTGAAGGAAAGGAAGATTTCCTTTTTTTTTATTCACTAATTAAACATTTAAAAATTAATGATATTCAAGTGGATTTTTATAATGGAAAGAATAACCTTAATAATTATTTTAAAACTTTGCATTTAAAACCAGGTTTTTCTAATTTGTGCTCTTTAGGGATTACTAGAGATGCTGATCAATCGTTCGATACTGCTTCTCAAAGTATTGATAATTCTATTATACAAAACCAATTAAATGAGAAAAAAAATTTAACCATCAAAAAATTTATATTTCCAGACAATAGTTCTTCAGGAATGTTAGAAGATCTTTGTTTAAGAGCGATTGATGATTCTGATATTGGTTGTATTACAGATTTTTTTCAGTGCATTAATAAAAACAAAAATATAAAACCAACTGAATTTTCTAAGGCTAAAATCCACGCCTGGTTGTCTAGTCAAGTAAAACCTGATAAACGTCTAGGTGAAGCTGCTCAAGCAGGATATATTGACTGGAATCACCCCAACTTTAACCCCTTGATAAATTTTATAAAAAGTCTTTAAATTTACTGTCCTAATGTTCATCTAATTACTCAATAAAGATAAAATAAAATAGTATAATTAATTATTCTTAATTTGATATTTATTTAGGGCTAATAAATTTAATAAATTATTTAATCTTAATTTTCAAAATAGGTATAAAATTCTATCATGTTTATTTGATAATTTATTCTGAGAAGATTTTATGAGTGCAGGCAAAAAGTTACGTCAAATATTAGAACAACCAGGTGCTCTCGTGTTACCAGGGGTTTATGATTGCATTGGGGCAAAAATTGTGGAACAAATAGGATTTCCTGTTGTTTTTACTAGCGGTTTTGGTATTTCTGGCTCTACACTGGGTCGGCCTGACTATGGTTTTATTACTGCTACAGAAATGCTCTATGCTATTAGGCGTATTACTGAGTCAGTTAATATTCCTTTGGTAGCTGATATTGATACTGGATATGGCAACCCACTCAATGTGATTAGAACTGTGACTGATATTGTCAATATGGGGGTTGCCGGAATTATTTTGGAAGACCAAGAATGGCCGAAAAAGTGCGGTCACTTTCAGGGTAAGCGGGTTATTCCTATGGCAGAACATGTGGAGAAAATTAAAGCGGCGGTTCATGCTAGGGGCGATAGTGGTTTAGTCATTATTGCTCGCACGGATGCTCGTGCTCCATTGGGTTTGGATGAAGCTATTAAGCGGGGACGTGCTTGTGCTGAAGCTGGTGCGGATGTGGTTTTTATTGAGGCGCCTCAGTCTCTGGAAGATTTGCAGGCGATCGCTACTGCTTTTGAGGATGTCTATTTATTTGCAAATATGATTGAGGGTGGAAAAACTCCGGTTTTGTCTGGTCAGGAATTGGCAGAAATGGGTTTTAAAATAGTGGTTTATCCTTTGTCAGGATTATTTTCTGCTACTCAAGCGATGATCAATTGTTATCGTCAATTATTTGAAAATGGAACTACGGCAGGGTTGCAAGATATTGTTTCGTTCCAGGATTTTGAAAATATTATTGAAGTGCCTAAATATCAAGAGTTGGAGCAGAAGTTTTCAGTTGATGTTAGGCATTAGGTTTTAGGTTTTAGGTTTTAGGTTTCAGGCGTTAGGTTTGAGGCGTCAGGTTTAAAAATTAACAAATTGATAACATCTAACTACCAAATTCATTGATTTTGGTCGCACTGTTAAATCTCCATAACCTTTTACTTCAATTCATTTTCAATTCTTTTTGTTAACCTGAAACCTGAAACCACCAAACCTACTCAAACTTAATATACAGCAGATTTCGGACACATGAGGTACAGGGTAAATGGTGAAAATTATGTAGTGCGAGTATCTTGCCTGCAAAGATCATCCTTGGTGTGAGTTATATCGTCAATATTTTCAAGTCAATTTACAAAAAAAATTATGGGTTCAGGTTTTCTGGAAATGTTTGATCAATAAATTTATTGGGAATTAAGCAAAAAAAAATCAAACAAAACCTCACTGACCGACTAAATTTTATTTTTTGGTAGTCTTGTATAGTAATAGTAAGATATGAGATATTTAGAGCAATAAAATTCAGTTTGTACCAGATAAATTGTCTTAAATTCCAGTCTACTAAAATTATAAGGTATGGACGTACTCACTATGCTAAGCCTCCCTTCCGTTTTCAGCATTCTGATCGACAATTTATGGAATATTCCAGCAGACAGCCTATTGATATCGTAGGAGTATATATTGGCGATCGCTCTAGATGATCAGCTCAAGGTCTTTGGTAATAATTACCTAAAGAAAATATTTCTTGGCATGACTCCAACTTAATAATTTATGGAACTCAACCAACTATTAGCACCAACCAAAAGTTTATTATTGTAGGTGATATTTCCTTAACTAATCTCCCAGAACTGCAAAAAAATCTAGATATTTCCCCTACTACTAATCCCAATTAAACAGTAGCTGAATTATGGCAAAATTGTGGTTTAGAAACCTTTTTATTATTAGAAGGAATTTTTGCTTTAGCAATTTGGGATAAGGAAAAAAGAGAACTATGGATAGGTCGCGATCGCGCAGTTTACGAGCTTGTTTTTCCTGATTCAAGACATAAATCAGTGGGGAATATTCAGGTTGAACAACTTATATAGAAAGATTAAATAATACTTTGCGTCAAAGAATTTCTCGGTTGGTCAGAAAGACTTTATCCTTTTCTATAAAGCTTCGGTCCCATCTAGGAGATATTTGGTATTTCATTAATCATTATAATGAAGCGATCGCTTCACTGTAATTTTATCACTACATATACAGGACCACCCAAAACTTTTAGCTCCAGTATTATTGACAGGGACGACCAATGCCGTGTGTTTTAATCATTGGCTTGAGCATCATCCCTATTCCAGAACTCAATCCCCATTCCCTGTTGATTATGGATAACGCTCCCTTTCATCAGAAGAAAGAAATCCGGGCGCTCGCAGCTCTTGATGGGCACAGTGTTTTGTTCTTAGGGCCCTACTCACCGGACTTCAACAAGATTGAAGAAGATTTGGCCATTCTCAAAAAGCAACGGATATATGCTCCACCAGAAACAACACTGGATGACATTGTTAGACTGTACGGAACTTAATTGTAATGACTATAGATATTAAACCAGCTCCTACAGCTCCAGATGGTGAAATTATGATGATCAAAGAGAATCACTTTTTAGATATATTTGATAGTGCTGATATGAGTTTATCATTTTTTGGGATTTGTATAAAAAATGCACCCTTATTAATTTTTGCTATTAGACTTTTAACTGCTGGATATCCTGCCAGAATTAAAGATAGAAATTTAGGGGCAAAATTACTAAATAAAGTCAAGGAAGTTGTGAGAGGTAATTATGATGTTAATACTTTTTTGAGTCAGGTTGATAATTGGTTTAATTTTCAAGCTAATTCTATTAATAGATTGCCAGAAAAAGTTCAGAACCAAAGGTTAACTGAACTGAGAGATTATAGAGATTGTTTGGTGGCTTTTTTTGCTAAATTTCAACCTAAAAGTTTGAATGATTGGAAAACAGAAATAGATAAGATTTTTGATGAATCAACTACTACTAAAAAAATTATAGATTTATATACTATTCATAGTGGTAAAGGTGGAGAAGGACATTATACATTTATTATTTATCCTGAGAATATGCCTATAGAATTTGAGAAGCAAAGCACAGAAGAAAGGCAGCAGGAACAACACATGATATACGTTGCTTTAACCCGCTGCCTGACTCGTGCTAAGGGTGGTATTTTGTGGTTGGTGTTGGAAGGGAAAAAAGATACTGTAAATTATCCAAAATGGCTACCACATGACTACCGGAAACTATGGAAAGATGATAAAGGTGAGTATTTTGAACTTGATTTTGAGGAATTGGAAGATATTGAGTTTTAGAATTTAGTTACAACTTTTTAAAATACTCTTGTGTTTTAAGTGCAACTTGACCGTATTAGCTAGTTTCAATACCATCATCAAGTCCTAATTCCTGGAGAGAAACTTTGGTTTCATTAATATTTTGAGATGTAATGCTTCCGGTTACAGAAAAATTAATTTCTACTGTTAAATTAAAATCTTTTTTTGCAGCAAACCTACTCAGAACTTTTGTATAAAATTGCATCCACTTTTGAGGTGTAATTTCTCCTCGCCAAGAAATTATATTAGGAATATTTGATGTTTCACCTTCAGTAATTTCATTAGTTCTATCTGACTTGGTTAAACTACTATCGGTAATATTATAATTTTCCGATTTTTCTTGGAGATGAGGTAACTTAAGCTCTACAGTAAATTTGGCTTTAATGCTAATATATTCTACTTGAGCAGTAACTATAAAATTCCCCTCATCTTTCCCGGCTGTTAAAACACCATTGAAGTTAATTTCTCCTCCTGTAGCACTCCAGTTAATTTCTTCTACATTAATTGACCGGTTATATTGGTCTTTTCCTGTCACTAAAAATGTTTGTTTTTGACCAGGTTTTAAGAGAACTTCTTCAGGAGAAATAATTAATTGAGTTAATCTGGGGGGGTCTTTAATTCTAGCTTCATAATCTTCTGCTACTTCTGCTTTAATTACAAATACATCATCAGATATTTCTACATCTTGAACAGAAAAGTTGGGTTGATTAAATATAAAAGGTTCATAACCATTTTTACTTTTCCCCACATAAGCTAATAATCCTTCCCGTACTCCATGAACAATAGCTTCTGGCACAGCTTTAGCTTCTAATAATCTAGGAAAAGTTGGGGAAGCAAAAAAGGCATCCTGAATATTTTTAATACTCCATTCTGTAAAAACAGGCGGCCAATTTCTGAGTAAAAACCGAGGATGAATGACGCTTGTAATTTCTCCATTAGCCTGTAGACGATTGATAATTAAACTTACCATTGAGTTAGCTTGACTCGAATTAAGCATTCCTAAATCAATCCACTGAATCTCTTGAATCTCTGGAATCTCTGGATTTTTTCCCCACAAAGCAACAGATGTATAAGACTGCCAAACAGTTTCTTGTAATAACTTTTTCGACTTGTCAATATTTTCCTTAAGTTGCTGTTTTTGCTCGGCATTTAATTCTGTTTCTTGGTCGCTAATATCCTCCCAAGCTAATAAATTTCTGGCTCGTTCTCTCAGGAGATTATCAGGATTAGCCACCACAAAAATTATCGCACTCTTAAAAGTTCTAGCTGAACTACCACAATTTAATATTATTGATTCTATAAATTTGCTTGTCTCCTCATCAGAACGAACATATTCGGGACTTAAAATAGCTAAATTCAGCACTGGTCGGTTGGCAATACTATTAGTATATTCTGGAAAATAAACAACTTGAATTACCCCATTAGTAGTAAAAACTTTTTTAATTTCGGCTGCGACTCTTTCCTGTATTCTAGAACTTTGTATATTGGCTCGACGGTCTGCTAAAATTTTATTCAAGTTGGGAGAAATATTAAACCGATATCTATTCTTATTTACCAATAAATAATAACTTTCATTTTGCAATGCTTCCAAAACTGTTTCTACATTGACAATATCAAAATTTGGCTCTCCCACTGCTAACCTAATTTCAGGAATAGTTGCTTCGGTGTTTTGTTGACCGCCATTAGATTCAAAAAATATAGTAGTTGCGACTTTTCGATGGAGACGAGATTTTTTAATGGTTGCTACTGCTTCCTTATCTAACCGGATAGCATGAGCATTCTGCTTACCACAAATATCTGTGGTGACAGCACCCTCTAAACGCTCTTCGCCCAACTGATTAAATACTGCGGTGCGAAACAGAGGGTCGTCTAGGGGAGCATTACCCAAACCAATGAGTGGGTCGTTGTGAACTTTTCTGTAACTTTCTTGATAGGCACGAGCAACCCAGAGTGCTAATAGTCTCAAAATACCCCTAGTTCGTTGAAACCTTGGTAAAACTTGCCACTTACGCTCAAATACTGACAAAACTGTGGGGTGAAATGGGTAGGTAGCGATGAATGCTTTTTGGGCGTTATCAACGTTAAACCAACTAGGTATTTGCTGGTGGTGGGATATCACCCATTCAGCGTATTCATTACAGGTGGCGATCGCATCTCTGGGCAACATAATTTTACCTTCGGTAGTAACCGCTTCTTTATCCCACTCAAACAAACGACGACGGATAATTTCTGAAGTTTCTGACTCTGCTGACATAACTATAGCTTTTCCCAGACGGTCTAACATTTTTTTAAGTCGTTGTTCGTCTGCTTCGTCTGCTTGGGTATATTCCATTTCTGAAGCTGGAATAGACACCACTAAAACAACATTTTCTAAACTTCTAGCTGTTTCAGAAAGTGCCTGCAAAAAATTATAAAAGCGGTTATGATATTCACGACTGCGATAAGTAGAAATATAGTTAATAATTTCATCCATTAAAATTAAACAGGGTCTATCTTTTGGAAATAATTTCCGAATCACATCACCCTTGGGTTCGATAAAATTTTTCTCATGTTCAGCAACATAATTAAAAGCTGTTTCTCCTCCTAATTGAAAAGCAATTTCTCCCCAGGGAGTTTTCCGTAGCGGAGTACCATCATTTCCACCTCTACCAGTAATAGAATCAAATTGTACTCCTACAAAAACTGCTACTGCTGCTTCGGGAATAGAATTAATTTTTGCTGTTTTGAGAATCTTATCTACTCCAGTCCAATTATTAGCTAAACTGCCATTTTTTGCTAAATGATATAGTAAAGTTAAGGCGTGAGTTTTACCCCCTCCAAATTGAGTAGAGAGGTTAAAAATAGCTGAAGTACCGCTAGTTTCTCCAGACAAACGACGGACAACTTGAGATGCTAAGTCGGTCAGAGATTTTGTTAAATAAGTCCGTTCAAAGAAACGCTCCGGTTGCTGATAATCTACCGGAGCATTATTGTTACGAACTTGGTCGAGATGAATGGCAAATTCAGAAGTATCTAAAGGTTTACCTTCTCGTAAATCTTCTCTAGGAATTAAACCATCTATTTTGTACCATGCTTTAATTGCCATAATGATAATATTTTTCTCCTTTTTTTGTTCCTAATTGAAGCTATAGCCTCATTCTGCTAATTCTTAGACAGAACACTGTAGGTGAGGTTTAATCCGGCAAACAAACAAAGTTCAAAAAAGTGTAAATTTGCCAATATTCACCTCCATTAACCACCACTTAAAGAAATCGTAGGGAAATGTCAAAGCTGCTTCTCTACTTCCTACTACAACTAAAGTTTCTCCCTGTAAATCTAATCTTTCTCTTGGTAAAATAGGTTGTAAAATTTCCCGTTCTAAATAATTAATTAATTCTCTTCTTTCTCCAGCAGTTTGGCAATAACAAAATACCACCCGTAAAGCCACTCGCACACAGAGAACTTTCCACAAAGAATAAGCACTGCGTTCCCAATTATTTTCTAATTCTATAACTGCAATAGGAAACTGCCAGCGTTGAGCAGCACCAACAAACGCCATCACATCCATTGTTAAAAACTCATTAGTAGCGACTGGCAACAACTCTAGAGAATAACCTTTAGCTGATGCTTGCCATCCCAATGTTTGACAAGTAGAAACTACTACAGCAGTTAAAGCTGAAGTCCACTCCTTAAGTTGTTTTTGCTCTCCGGCAGTTTGGAGAGTTTGAGCATGGGTAGGTTGTTGTACGACTTGCCAAAAAGCCGATCGCCATTTTTCAGCTAAGTTAGTTTGCACTTTTGAAAATTACTCTCCCACTGACATCAAGACTTGATTCATTAATCTCTCTGATAGATACATTCCAGACAACCTTAACTGTTCTAAAACAGGACGTGCTTCTGAAATTACTCCACGTTGTTTGGCAGTTAAAACTAAACCCAAAGTACCTCTCACCGGAATTCCTAACGCTTGGGCACAACGACGAGCAGCTAAATCATCAATAATCACTTCTGTATTTGGGTGATGATACCCCCAACTCAAAACCTCTGATTCTCCTGCTCCTAAATCCCAACTTTGAATCACAGCAGGAATAGCAGGAGTTTGAGTCACAACTAACCAATCTGTTTGAGCTAACATTTGGGCAGTTACATCTGTGTTTCCGTAGGCTTGAATTTCTGTAGCTACTGCTTGAGGAACAATAATTTTTGGACTCAGCATTTGCAGGAAGTTGAGCAAATTTGCTTGAGTCAAAAAAATCAAAGGTGAAGTATTTACTGCCGGAAATTCAGCCACGCTCTAACTCCCGTTGCAAATCATTAAAATCAACATTAAACACATCTATTTTTTCCCTTGCTAAACTAGCGAGAAAATCTCGACGGTTTAACCCGGCAACTTGAGCTGCTTTTTCTTGAGAAATTTCCCCTTTTTGATACCAATATATAGCTGCTGCTAAACGCATATCCCGAACAAATTCTTCAGGAGCTAAACGGCGGGCAGAAAAAATTTCTTCTGGTAAATTAATAGTAATTTCTGACATGATTATTTATGTAAAATTACTGGGATTTAATCAGATAAAGTAGAAAATTTAATGGACATTTTAGACAATATCCTCATAACAATTTTACCATTACTTCTGCTAAAAACCCAATCCTTTTTTCCTTGCCAATATTCCCTCTAACCAACGTTTCTCTTCCACATTCTGAGGATATACCCGCAATAGGGCATCTGCTAAATTCCAAAATCTGGGGTCTTTGCCTACTCCCTCCTCTACTAATAGTCGTTTCACTGCTTCGCTACGTCCTGTTTTGTGTAACAACATGGTTTGATGTATCCGGTCTAATACGGTTTTGCCTATCTCAGCGATCGCTATATCTGCTTCTACTTCTATTTCAGTTTCTTTTTCTGGCAAAATACCTTCTAAACTTAGTTGTTTTGGAGTCTTACTTTTGCGTTTTTTAGTATTAGTAGTAGGGGCAACTTTTCCGATTAAATAATGACTCCTTTCTTGTACTGGTAAAAGTCTGGCTTTATTACCTTTTATTTCTACTAAATGGGTGAGGTTTTCTAGGTGCGCTCCTAAACCTTGGGCGATTTTGCGGGCGGTGTCAAACTCTAAGGCAAAACCTGTAGATTTTTGATTTTTGCTGGCGGGGGTGTCTTCCTCATCTTGGTCTGACTCTGTTTCTGTTGCTGATTCGGTGCTGCCAGTAGAAAGCGTCCATAACCAAATGACTGTGAGACGAGCGTCTGCTTCCAGGTTATTAGTGTCAGCTTCCGAGAATATCTGTTTTAAGGCTTCGTTTGCTACTGTTCCCCAGAGATATTCTAGGTATTCGCCCAAAGTGACTGGTTGCCCATTGACTTTTTCCACGCTGGAGTAACGAGAGAATATTTCTAGGGCGGGTCCGATACAAGCAAAGATAGCATCAGCACCGACTATACCTTCTGATGTCAGACGTGGCATCCAGTCTTGGATGCGTTGGGGTAGCTCTTGGATGATGTCGCGCCAGTCGCCGATATTGTTATTGTTGCGGGGTCGGCAAACAAGATGGATGGATGAGGCGAGGGCAGCAGAGTTTTGGGCGCGGGGTCTGTTGCCCCTTTCTGTGTCTATTGCCCAGGATGCGGTTATTTTCCAACCAGCATCTATCATTGCTTGTAGTTGAGCTTCCCATCCAGCAGTTGATTTGTGGGCAAAGACAATAATACCTATTCCGTCTGAGGATATGATGCGACATCCTTCTGCCATTGCTTTTGCCATCTGGGTTTCAAACCATTTGCCGTTTTTGTGTGGGTATCTTTTGGAATCCCATCCTGCCATTTCACAAATTTCATCATCTTTCGGAGTAGTTTCACTAGAAAATAAGTTGGGGTAGGTTTTGTTTAGAGTTCTTTTTAGCCAGACATAGAAAAAGTCGGATAAGTCAGCGTAGGGTACAGCGTTGTAATAAGGAGGATCGGAAAAGAAGCATTGAGTAAAGTCGTCTGGTAGGGGGTGACTCGCTGCATTTGCTTGTTGGGTTTGACCGGGGTCGGGTAATAATGATGCTTTGATGACGGATAAAACCCAACTGACAGCACCTTGCCAGTATCCGTCAGAACCTCCCACTAGATTTGTTTCTCCAAAATCCCAAAGCATGGGTAAAGCTTGCCTAGCGAAAACACCGTCTATTAACTCTCGACTGTTATTCCACTTTGATAGAGAGCAAAACTGATTAGTGCAGCGATCAACTGCCAAAGCCAAACAAGTCTGAATAGCGATCGCCAACCTTTCATCCTCATTACTAGCCAATTTTTTTCCCACTTCCTTAACTAACCTCACCAAAGTAGTTAAAGCTAAAGCTTGACGAGAAGAAAATAAACTTCCCCAGGTGTTATGTCCGTAAATGGGCGCATTAAAAACACCGCTCATAACTGGCACCGGTTCATCCGGCACCAAACTCAACTCCCCACCATACTCCAACTTCCGCCTTGCCAACTCCTCACCTGCCATTCTCACCGCTTCCAAATCTCTCTCATTGGGCAACCGATAAAACCTACCCTTCACCTTCTCCCTAGTCGTCACCACACAAAACAACCGGGCATCATCCGCACCCCCACCCCTTGCTTGCAACTGCTTTCGCACCGAAGCCACCGGAGTCGTAAACCCACAACAAGGACAAGTCGCTGAACCTCGTTTCACCGTTCCATCCCCAACATCTTTCCCTTTCACCTGCTCCACAATCTCAAAATCAACTCGCTTTTCCTCCTGCCGAGGAATCAACCGTAACGCCACCGACCGATTCTTTTTCTTTGCCAACCACAAACTCCGCATCAAAGGAACCTCCGCCCCACATCCAGGCCCCTCACAAACAATCGTCCGCGCCCAAAGATAAGCAATAGGTGTTTCCACATCCCCATTCTTAAGTGTTGCAGCAGATTTAGGATAAAACTCCCCCAATTCCTTTTCTGCCTCCTGCTTTATCCATTCTCCCCACTTACGCACCTCATCCGCCAAAGTTTGCCCATACTTAGGAATATATTCCAACACAACCTTATTTAACAAAACCGCCACCGGATTCAAATCAGAGGCAAAAGCATCTGCTCCTACCCGCAAAGCCTCCAAAGGAATCGCACCTCCACCCGCAAAAGAGTCAAAAACTACGGGTTTTGTATCAGTAATTCCTCCTAAAGAATAATGACTAATTTCTGTTAGTTTACGACTGGTTTGTAAATAATCTGGATGTGTAGAATTATCCCAATTAGCAAAGTCAGCAATAAAGTCTAATAAGCGATAACGGAGTATGTTTAAATGTTCTATTTTTTCTGGATTTAACTGATTTTTAGGTTTAGCTAAAACTTGCCATTTTTTTAGGTTTGCTGTGGAGCCATGATTATCTAAATTTTTATCAACTATTTTGGCAAAACCATTAATAACTTTTGCAGCCTCAACCCGAAACAATTCCGGGCAATTATCATCAACTGGGTCTAACCAAAGAGCAGCACAAATTACAGCCCGACAAGCAGCCAAAGGTCGTCTTGCCCACCAAATATGTAAGGTCGAAATATGACCGTGACGAATTGATTTTTCTCGTCTAGCATGGGCAGAGATTTGTTTAATTGGGAGGTCTACTTCAATTAAGCGTTTGGGATAATTTGTCATTTTAGTTATCAGTTATAATTTATCAGTTATATCATGTTTGGAGCATCAACTAAAATACACTTGCTCTCCCGAAATACCTATTGAATGACAAATACATAACTTCTCTGTTTTGTCAAGTTTTATCTTAAGAAAAATATTTATAAAGCATAGCTCTTTCAAGAGAATAAGAAAAAGAACATTCCATACTTCAAACCTCTCTATTACAAGAGTTACTAATAAATGACATAACAGACATCCTACCTGTTATGTCAGTTATAAACTATCCATTACTTTATTGATACTTTATTGACTAGCACTAATAATTTTACTTGCTTCAACCTGATAATGTTCAATCTTATTCAAAGGTTCCCACCCTAACTTTACCGGGTTATTAATCGTATAAACTTCTGAATTTGTCGCACAATTAAAAACTACATAAAGCCAATAATCTCCTTGCAACCTAGCAGCAGTTTGATACTCATTATTTGTTAAAACCACAGTACCTACAGTTGCCCTACCTTTTACCTCAATAAATCTTACACTAATAGCCGTTTGAATATCTTCGGGATGAGGTTTCCGAGAAATCAAATCAAAACCCCGATTTTGGTTTTCTACACTCTCCACTTGCCAACCCCTCCCCCTTTCATACTCCATTACCTTATCAATAGCAATACACTCAATATCCCGATCGCTCACCATAGGAGCTAACTCTGGAGAAGAGCGTTCTGGATGGGGCAAAACCAGAGCGCAACCATAATGATGCACCCCCGAAATAGCACAACTCGCCTCTTTTTCCAACTCCTCCCGGCGAGACTCCAACCTACCATTCAACTCAAACAAACGGTCATCCATCTGTTTTATTCGCCCATCTAACCCTGCCTCCTTAGAACCCGCTTCCTTTTCTGCGTGTAACTCAGCAAACTGGCATTGTACCCGGTCAATAATTGTATTCAAACTAATCTCTGTATGATTAAGAATACTCTTGACTTCCTGCTGACGTTGTGCTAAATTTTCTGCCAAGAATGGCTGCAACGCTTTTTCATATAGAGCCAATTCTACCCATTCTAACCTCGGTCTTTCCATATCCACCTCTGACAACTCCGACAATTCCGCCACAGCTAAATCTAAAAACACAGTAGGTTGACGTACTATCATTTCACCATCAGACCTTGTTTCTACTACAAACAACCGCTCATGCAGTTTCCGTCCCCGACCATCCACAATAGCAGCAGCAAACACATCTAAATAACTAGGTTTCCGGCGATGCAAATCATAAAATATTGCCCCCCGTTGTAAATCTTCCGTGACTATTTCCCCTACTTTTTCTCGCACACATTCAAATAAAGGATGCCCCGGTGTCACCCATTCCAAGGTAGGGTCACTTTTGAGTAAGTCCTTATCAAAGATAATTTTTTTATATTCTCGCCCTAGTTTGCCATATTGAGGTTCCAAGCGATCGCCCACAGACCACAAAGTACGAGGCAGTTTTCCCACTCGATAAATGTGGGAATTTTTCTTGACTTCCTTAGGATGAATACCTGCTATGGGAGCAGCTTTGAGAAAGAAATTTTCAATACTTCTTGGCATCAGTCGGTTTTCCTTAGCTTCAGTAGACTTACCTATTAATTTAGATAGGTTAAGCTCCCGTTTTGCTAATCCTTCTAAAGCTGAATTAGTAATTTTTTGAAAATGTTTGCTGTCTACCTGTTGGACAATTCTATCTTTGATACCATCCTCACTAATATTACGAGCATACATATCTCGTAACATCTTTTCTAGTTGGTTAGCAGGAAAAATATCTCCCAAAACATTAAAGACTTTACCCGTATTTTCGGGGTCTAAGTCAGCTTCGATGGCGTAAATACGTTCAAACAGTTTCCACAAAACCCTACCTTCTCTGGTATTAGTAGCAACAAAGTTAAAAATTAGACAGTCTTTTTCCTGCCCATAACGGTGAGTTCTACCCATACGTTGTTCTAAACGGACTGGGTTCCAGGGAATATCATAATTAATAGTTAGCCAACAAAACTGTAAATTAATACCCTCTCCTGCTGCTTCGGTAGCAACTAATATCTGTGCATCTTCACGAAACTCTCGTTCAGCGTAAATACGAGTTTGGGGAGTATCCCGGTCTCCTATTTTCATCCCCCCATGAATTTGAGTTACTGATAATTTCCAGCCTCGAAGTTTGCCAACCAAATAATCTAATGTGTCTTTATGTTCGGTAAAAATTAATAGTTTCATCTTCCGGTCTTGGAAAATACCTTTGCTAGTTATTATTTCTTTTAGCTTGACTAATTTTGATTCTATTTCCCGTTTTTCTAACTCTAAAGCTAAATAAATTAACCTGGTTAATTGAGCAATTTCATCTTGTAAATTTCCAGGATTTACTGAAGCTACTACTGACTCTAAACTTTCCCTGATTTTATTCTGTTCCTGCTCAGTTAAATCCTCAAAATCATTAGGCAAATGACGACTAATTTTTTGTTCTCGATAACCTTGAGGATCATCGATAATTTTTTGTCGTTTTTCTTTCATCCGTTCCAAACTGCGACGGATAGCAAACATACTAGAAGCAAACCGACGTTGTAGCATTGCCATAGTAAAACCTAATGCTCTTCCCCTAGCAGAATTATCTTTAGAAGCTTTAATTGATTGGTCTTCAACATAGCGAGTTAGAGCATCGTAAAAGTCTAATTCAGCATCATCTATTTGAAATTCAATAGTTTCTACTTTACGGTTAGGAAAAAGTTTTTTTACTTCCTTAGTTTCGGGGTCAGGAAATGTGACAAGTGCTTCTTTTGTTCGGCGTAAATAAAAAGGAGCTACATTGTTTACCATTGCCTCCTCTAAACTTCTCACATCCCCATAAACATCTTTATCTAATAGTTCTAAAAATAGACAAAAATTTTTAGGGTCACCTTTGTGGGGAGTAGCCGTCATTAATAAATAATGATCAGTCATTTCTGATAGTTTTTCTCCTAACTGATAAGCTAAAGTTTTTTTATCAGATTTATAAGCACTCATTTTATGGGCTTCATCAACAATAATTAAATCCCAATTAGAACGCAATAAACTTTCTTTAGCATCTTGAATCCGAGAAACCCAAGAAACAGAAGTAACAATTTGAGATTTTTCTTGCCAAGGATTATTACCATAATTAGCTCTGAGAATGTCACCTTTTACTACTTCAAAATCTTCTCTAAACTTATCCTTAAGTTCCCGTTGCCATTGAAAAGTTAGATTAGCAGGAGCTACAATTAATGTGCGTTGAACTAATCCCCTAATTTTTAACTCTTTCAACAATAAACCAGCCATAATAGTTTTACCAGCTCCTGGGTCATCTGCTAGTAGAAACCTAATTCGAGGTAACTTAAGAAAGTAATCATAAACGGCTTCTAACTGATGAGGTAGGGGGTCTACACGAGCGATCGCTAAGGAAAAATAGGGGTCATATTCGTAGGCTAATTTCCAACGTAAGGCCTCTACTCCTAAGCGAAAACTGGCAGAATTGCCATCAAAAAGTTTGGTCTTGGTAATAGCACTAAGAGAAGCAATTTGTTGAGGAGTAAGAATAGGGTCATAAACTTGATTTGTTTGAGTTCCTTTACCAATTAATTTGATAGATTCCCCCATATGATTTGTAGTAATTATCTGAACTGGTTCAGAGAACAAAGAACCTGTAATTATTATGTTTGGTTGCAGTTCTGTTATTTGCATTTGTTGCAGATTATTTTAGACTGGGGTTGACAATAGATAAATTCTACCCCGATGAGGTTTTATTATCAAAACTTAACTTAAAAAGAAAGCAGAGGATGGGTAGGAGTAATTTATGAATTGCTTCTTATTGTGCGTACCATATTGGAGAGTTTTTAAATCGGTGCTGAGTACCCAATTCGCAATCGCAAGCATCTTCTCTTGAAGTTCTCGCAAATTATCTAAAATTATAATTTTTTTTGAAAAAAAATACTATAGTTCGCGTCATAAAGTGCAAGTTTATAAAGTTTTGTAAAGTTGCCTCTCACTGCCTGCTACCGTTTACTTTATCCTATTAGTAATACCATATAGAAAACTATACAGGTTTTGAAATAGACTAAGTTCTTCAAAGAAATTAGGCCCTTTTGGTGTGACAAAGCTCTTGGTTAGATAGAGGATTAGTTTTGTGTAAAGAGGCAAAGCTAAACCAGGATAAACAGGTTTTTGAGCCTATCCTACCTAGGAATGTCAAAATTGTCTCTGACAACTTGTCGAAAATAGTCAAAGAGATTATATTAGTAATGAAACCCAAGAACTGATTGATAAATTAAAATAGAGAAAAAATTAGTTTGGCTGGTATAATCCGTGTAATAGGTATGTCAAAAAAATAGCCCCAGAATTACGTCAATAATAAGTATGCTCAGGTTTCACGCTCTATTAAATGTACTAAAAAAAACCGGTAAACTCACCATTCAATGTGATGAAATGTGGTCATTTATAGGCAATAAAAATAATAAACAATGGCTGTGGTTAGCGATTGATATAGAAACTCAATAAATTGTGGGTTTCTACTTAGGGGAAAGAGGAGAAAAAGGGGCAGCATAGATTATGGAATTCTAACCCACGGTGTCTTAAGGCCGTGTGCAGTTTGTTATACAGATTTTGGGTCAGCTTACGAGCTTGTTTTTCCTGATTACAAGACATAAATCAGTGGGGAATATTCAGGTTGAACAACTTATATAGAAAGATTAAATAATACTTTGCGTCAAAGAATTTCTCGGTTGGTCAGAAAGACTTTATCCTTTTCTAAAAAGCTTCGGTCCCATCTAGGAGATATTTGGTATTTCATTAATCATTATAATGAAGCGATCGCTTCACTGTAATTTTATCACTACATATACAGGAACACCTAAATTTAAAAGTGCAGACCATATTTTAACCAAAGTAAATAACATGACTAGGGCGAATAAATTAATCGGACTTTCCCCATTATTTGACCAAAGAATTGTAGAACTAAGTTTAGAAATTCTACCAAAATATAAATTATCCGGCGCAGATGAAAAAGCAGTATTAAAACAAGCAGTAGCAGACCTATTACCAGAGAAAATATTAACCCGTCCCAAAAGTGGAATGATGGTACCTGTTAACTTTTGGTTTCGTAAAATATGGCAGCGTCGAACCAAGAATTTATTGTTAAGTAAAAAAGCAGCGATCGCTCCCTATATCAATCAAGATTTAATCAAAGATTGGTTAAATTATCAGGGAGATACTTGGAGGCGTTATGGAATTAAACTTTGGTTATTAGTTAGCCTATAAATTTGGCTACAAGTTAATCGTAAATAAACTAATATAAGCTAGACTCAATAACAAAAAAATCACAATTATTGGTAAGTTTTGTTGTAGCAGTAAACCCAACATATATATATAATAGAAATCGGTTTTTGTTGGGTTTACCTAGAGCTTAACCCAGCCTAAAGTATTATGAGTATAGCTTCAAAAAACATAGAAAATTTAGACTTGACCAAAACTATCAGATGCAAAAAAACCTATATTTTGACTACTACTATGTAGGTACGTTCCATGGAACGTACTCACTGTAGTCTACTAAAATAAAAAGCGCTGTATTGGTTGATATATCCCTTGAATTATTATCAGGTAGATGAAAAAAATCATTACTTGTTTACCCCTACCATCATTCTTACCTTTGACTTTCATTTCCCATGTCGTTTTTGATGCCACTGCCAAGCATGACTAACTATTTCCTTAACCTCTGGATATTTCGGAGACCAACCCAACACTTTCCTGGCTTTCTCACTACTCCCTACCAAAATAGGTGGATCTCCAGGTCGGCGATCGCGCTCCTCCACTTTAAACTCTCTACCAGTTACTTGCTTCACAGTCTCTATCACTTCCCTAACCGAAAACCCATTACCATTGCCCAAATTAAAAATATTGCTCTCACCACCATTCAACAAATATTCTAACCCCAAAACATGAGCATCCGCTAAATCACACACATGAATATAATCTCGAATACAAGTACCATCAGGAGTCTTATAATTTGTGCCAAAAATTGATATAGAATCTCGCTTGCCCAATGCTGCAAACAATACCAGAGGAATTAAATGAGTTTCCGGGTTATGATCTTCCCCAGTCAAACCATTAGGATGTGCTCCTGCTGCATTAAAGTAGCGAAAACAAACCGACTTAAAATCATAAGCGATCTCAAAATCTGCAAGTATTTGCTCTATCATCCGCTTACTTGCACCATAAGGGTTAATTGGATTTTTCGGATGATCCTCGGGAATAGGAATGGTTTGTGGTTTCCCATAAATAGCAGCAGTTGAAGAGAAAACAAACTTTTTTATGGATGCTTTAAGCATCGCTTCTAATAATGTTAGTGTCCCAACTACATTATTGTGGTAATATTTCTGCGGATCCTTTACTGATTCACCGACAAAAATATATGCTGCAAAATGCATTACTGCAGCAATGTTGTGAGTAGCAAAAATTTTATCTAATAAAGAGCGATCGCTAGTATCCCCAACAATCATTTCTACCTTCAGGACATTTTCTACAATGTCCCGATGTCCATAGACGAGGTTATCCAAAATCACTATATCATAACCTGCATTTTGTAAAGCCTGAACTGCATGGGAACCAATATATCCTGCTCCCCCACTCACTAAAATCGTTGGCTTGGTTTGTGACACTTTTTCAGTTTCCTTTTAAGTATTAATTTAGCCTTGGTACTTGGCACTTATACCCCAATACAGTTCACTTAAGGATTTTTTTAGGCAGTTTTTATCATCTGGGGAGCTACTCTAATAGTTCCATACATACCTGAGTTTTGGTCTCATCTGAACCCTATTGAATCATAACCGGAGCCACCAAAAAATTAATCTTAAAAGATCCCTACACTATATTTAATTCTTTCTTATCACTATACAGCAGAAAATTTCCAATCTCTTTGAGGAGATTGGAATTACAGAAAGCTACTATCAATCTGGAAACTTTTGTGTTATGCTTTTAATACGAAATGTTTTTGAATAACTTGAGGAATTTCTGCTGAACGAATACGACTATATTTAGCTTTCTGGGGCATAACTATTATATTGGGTCCAGCTTTACATTTTTTCAGACATCCTGTCTTCTTGATTTTTACCTGGTCTTGTAAATCATGCTCGCTCAATGCTTTAGACAATGCTTTACAAATTTTACTTGCACCTCGTTTTTCACAATCGGATTTTTGACATACCAAAATTTCAGCTTTTTTACCTACACATTTAGCATTACCTTCAGTCGTTTTTTGAGATTTACTAGATATCTCCTCAGTATCGGGCAACTTCATTTCTGTTAGTTGACTTGATGACTTTTCAAGTAATGCTACAGGCTGACTTGGCCATATTTCTGTAGCTTTTGCAGTAAAATCTGGTGTAATCTTAAAAGCCTTAAGCTCTTCTTCACCAGTTTTTTTACATAATGCCATTTCACCTTTGATTTTCACCTCTAAACCTGGTGTTAATACTGATGAAAAGTTTCGCCGTAAATGCTTGGCTACTTTGACAACATAATTATTTCCGGCCAGTGTCTCTACATGAACATATTTCAGCTTGTAGCCATCCTTGATAGTAACTTCTTGGACTTTTCCTTCCAGGCTGAATTTTTTCTGACGCTTGAATTTAGACATTATTGGTTGCTGTATGTTTACTAATAGTTATCTGTGTAGCTTGGGATAAGTTTAATTACTTAGATATAAAGTTTTTTATCTCTACTTTACAGATAAATACATTACTTTTTTCCCTAATTAATTCATGTTATTAATTAGGATATTAGCTAACCTCCCAAGAACTTTGTAACAGTTGAACTAATTCATAACGATGGGCTGTGAATTGTTTCAAGACACTTTCTAGTTGATTAGCTTCATTTGTGTTTTTTAGATGTACTTGTAATGGCTTTTCTGGTTCACACCAACAATCAATATCTAATTCTTGTAAACGTCTATATACTTGCCATCTATCTACACAGCTTACTTCTACAATTTCACAAATTCCTGGCTTCTGGTTAAATGTACTCATTTTTTAACAATTGAAATATTTTCGCACTAAATTTATATGTAAGCTCTGGTGGAATTAGAGTATATTTCTACCAGTCAGCCTTTATCCTTGAGTATACAATACTTAAGAAATTTTCCCAATAGTTTGATAAAAACTAGTTTTTAACTCATAATGTCTTTTATCTGTTAACCTGACTCTGGTTGACTCTCCTAGTAACTGTGGTAAACTTAAAACTACTAGCAATCAAAAAGCGCTAGACTAGAATAGATAGACTAAGTTAATTTACAAATAAGGAATAAATAATATGTCTAACGGCACAACAGCAACTCCAGTACAGGCATTTGGTCAGATTGCTGATAACCCTATTGGATTAGAAAAAAGTGTTACTGAACCTGTATGCGAGGGTATGAATGTAGCTTTGGCCAGTTGCCAAGCTTTATACCTCCAGTATGAGAAACACCATTTTGTCGTAGAAGGAGCAGAGTTTAACCAACTACATGAGTTTTTCAAAGAAAGCTATGAGGAAGTTAAAGAGCATGTCCATGAGATGGCTGAGCGTTTAAATGGTCTAGGTGGTGTTCCAGTTGCTAGCTTTGCTAAGTTAGCTGAGATGTGTTGCTTTACTCCTGAAGAAGATGGAAGTTTTAATGCTCGTAATATGATCGAACACGATCTAAAAGCAGAGCAGGATGTAATTAAGTTATTACGTCGCCTAGCTGCGCAAGCTGAAAGCTTAGGCGATCGTGCTACTCGTTACCTGTATGAGAAGATTCTACTGGAGACAGAAGAGCGTGCATATCATCTAGATCACTTCCTTGCTCCAGATACACTAGTAGTATTGAACTAAGTTAATTATCCTAGTTAAAAACCTGCAAATTCTAGAAAAATGAACAGAGTAGATATAGATAGGTAGATACAACACCCGGATTTTTGTTTGTAAGATCACAGTTTAATATAACTTACAAAAACCTAAACTTTGGTAGAGGTAGCCAAAAATTTAAGACATTAAAGTTTCATTTTTTGCCTTTTCATCTTCTTAGAGGAAGAAGATGTTATAAAGCACCTGGCAGAGAGGTACAGTCATTCTCTCTGTCATATTTTTTTGCTAGATCTAGTTGAACTAGCTGTTAATTTAATTATAACCATGTTGCAAAAATTTAGCAACTACCTTGAAAAAATTTTCTTTTTTGTTAAATTTATTACTGAATTCCGTCATTTTATTTTACTAATTGATTTAAACCAGCTATCGGGAATAACTAGCTTGCATTTGTTTTGTTATTACATATAATCCATAGTCCAATCCGAGTAATTGATTTTATTTTGTCAAAAGTCAAAATAAAAAAGTCAAAATAAAAGAATATGACTATATAACCTTAAATCTATACTATACCAATTTCCCAAAATAATATTATATTTTTTTAATAATTCAATTATTAAGTAAAAATTAGGTCTAATAATGGATTTAACTGTTCAAGTCTCTAATTACATTAGAGCAATATACTTATTGATTTGATCCAATAAAAAAAAGTCTGAAGCCAAGGAAGTCTCACCAAAAAAAAATAATATTGTCCATCTTAGCAACTAAGCACTAGGTATGAAGCGAAGATATCTCAATTCCTAATAACCCTAAGACCTAGGGACATTTCATAGTGCCATCTACATCAGAAAATATCTCCTACGTCTACAATACCATAGTATTAGGGAAAAACGATATAATAAGGCCACTTTTAAGTATAGGAAGTAGGAAAAACTCCTGTAGATAAAAGTTGGCAATAATAAAGGGGCGAGGGCAGTAATTTAAGCCACCCTATATATGCTTGAAATTCTAGTATTACGTCTTTTGGTTAGGACTGGGAAATTTTGCTTGTAATATAACAGGCAATAGGAGATGGGGAACAGAGAAATGTCCTAACCGATTTGCGTATTGCTATAGATTTGTTGCGTCGGCAATACAACTAATTATTAAGGGAGGGGATCTTTAGGGGATCTTTAGAAATGAAGAAAACCCTTGTCCAGTTAATGTTGGTCTATTAATAACGCCAATTCCTCAACTCAGAGATAATCAAGATTATTACTCCCAGAAAAAGGATTTGCTAAATACCAAAGACAAATTTCGAGAGTACAAATTAATTCATTCTCAAGTATTGCAAGATTGCATTAAACAAGTAAAACTAGGCTTTGATAGGTGTTTTAAAGTAGATAAAAATGGGCAAAGATTAGGGAATACTCAAGATTTAAAGGAAAAGGTTGTTATCGTAACTTCACTTATCCTCAAATAAAGTCAGACTGTGTTTAAGGAAATAAAATTAATTTACCCAAAATAGGTAAGGTAAAGTTAATTAAGATGGTTTTAAATAAAAACAGTTACTATTAGCCACAAAGCTGATGGGTATTATGTTACCATGTAGTTCAAGGATAAATCAGTTCCCACCTTGACTGCTGTTGTCAAACCTGCCTGGGATAACACTTTGGCTATTGATTAGGGTTCTGAAAGATTTTTTTGATAACCAAGGAAGTAGTATGACTTCCAATTCCTCAATATTACCGAAAGTCTCAGAAGTGGCTAAAGACTTTACAAAAAGGTTTATCTTGAAACAAAAAAGGCAGCAACAGATCGTTAAAGGCTTTCAAGTCAGTAGGTAAATAATATAAACAAGTGTGAATAGTATAAAAGCACTTTAGTGATAGCAGGTAGATTTTATCCGAGTTCTCAGATATGTTCTCACTGTGGGTATAAACAGAAAATGCTATTACATAAGAGAACTTATGAATGTGACAACTGCGGTTTGAAAGCAGACAGAGACTTTAATGCTGCAATAAAGAGCAAAAACTATGTGAATAAGTAGCTTGAGTCAAAAGCGATTTTGTTTCCTGAAGATGTAAGAAATGAGCTGGCTTAGTTTAACAATGTTAGGATTACTCATAGTTTTGAGCAAGTGTAGTTAGGAGTATTGACTTAATCAAAGAATAACGATATAATAGGCAAAAAAATATACTATTTAGATAAATAACCCGGAAAATACATGAAATCCATCAGGAGCAAACTAAAATTAAATAACCAGCAAAAAACTCTGATGGCTCAACACGCAAGTTATAACAGATGGTCTTATAACTGGGTTTTAAATTGGTGGAATGTTGCTGATAAAGATGGTTATCAACCATTAGCCATTAAACTCAGAGAGGTTTTGACGAGCCACACAAAACCTCTTGAACCCTGAATAAAAAATTTTTCCTCTAAAACTGAAAAATTTATATAGTAAGTTTTTGAGCAGTTTCAGTTTTTATTTTCCAATAATTCTATTCGTAGAAGGTAAAAGTCAAGAGTCAGTAGTAGGTTTGATTTAATTTTTCTTATTAAAAATATGGCAAAATCCCTAAAACCTGAGGCATTTTTTCAAGCACCAGGAGTCATCCTTGATGTTCGCAGTCCTGCTGAATATACTCAAGGTCATATTCCTGGCGCTGTTAGTTTTCCTCTATTTAATAATGAAGAACGGGCTTTAGTAGGAACTTGCTACAAACAAAAAGGTAAAGATGAAGCAGTAGAGTTAGGGTTAGCGATCGCTGGTCCGAAATTAGCTGATTTTGTTGCCTATGCTAAAATTTTAGCTCCAGACCGTCAAGTCAGAATTCACTGTTGGCGTGGTGGAATGCGTAGTGCTTCAGTAGGTTGGTTACTAGAAACTGCTGGGTTTAATGTGGCTCTACTCATGGGTGGTTATAAAGGGTTTCGGCGTTGGGCACTTTCTTTATTTTTAGTTCCACAAAAAATTATTGTTCTGGGTGGAATGACTGGCAGTGGCAAAACTGAGATTCTGCATGCTTTAAGAGATATGGGGGAACAGGTATTGGATCTAGAAGCTCTTGCAAACCATCGGGGTAGTAGTTTCGGAGCTTTGGGGCAGTTACCTCAACCTACTAACGAGCAATTTTGGAATAAGATAGCAATGGAGTGGGGAAAGTTTGATTCCACTCAACCTTTATGGGTTGAAGCTGAGAGCAGAAGTATTGGGTTGTGTCGTATTCCCCAGGAAATTTTTGAGCAAATGGAAAAAGCAATAGTTATTGAAATAAGTCGTAGTCGTCAGGAAAGAGTGGCATTTTTGGTAGAAATATATGGGGATGCAAATATTGATGATTTGATTGCTGCTACCGAACGCATTCGTAAACGCTTGGGAGGTCTGCGAGCGCAAAAGGCAATTGATTTTGGTAGAGAAGGCAATTTAGTAGCAGCTTCAGATTTAATTCTTCACTACTATGATAAAACCTATACTTATGATTTGGAAAAAAGGGGTGGTTATATTTATAAAGTTAATGTTTCTGGTTTATCAAATCTTGATGCTGCAGTGTTGGTACAACAAAAAAGTCAAGAGATTCAATAATTCAGTTATTTATCATTAGTTAATTTTCCTGATTTTTTTTGTCAATTTTTTTTTAGTCAAATAAAAATACTATGTCTGGTTAAATATCCATAGATATAGCTTTAATGAGTCACCTATCATATCAAATCTGGTAGCATGGGAGTAATTCAACCTAAATTTTTACTCCACCAATTGTATAGTAGTCAAAGCATAGCTTAAGACATCAATTTCTGTATAAACCGAAATTGAGAAGAGAGAGAGCGTCTTAAGCTTTTGTTAGATTTCTATATTGGGTTAGGACTTACACAACAACACTAATCATAGTTCAAATACTCAAAAACTACACTATATATAGCGTTACTATGTAATTCCTGTAGGTTATAGCCTTGATGAGAAACTGCTGTTTTCAAAGAAGTTGACAACCCTCAAACAAAACTGCTTCTAGCTCCTCAGGGCCAGCAAATGAATAATTTGCTATCAGTTCATCAATTAGAGGCCATAAGCCCTCTGCAGGTTGTAAATAAGAGTGAGTAGACGGGGTCATTACTCTAAGTACAAGCCCAAAGGAGTTTTTAACTCTGAACTTGTATGCCATCCAGCTGTGTTAATGGTTAAGAGGTGATTTATAAAGATAATCTCAAGAAAGCTTTGTCCAAGTCAATAATGGTGTTCTTCTTAATCAGACTATTGTAACTAATAAACTGCCTATTTGCGATCGCAAATCATCAACATCAACACCAAATTTAACCCCCCTTCAGGCAGCTCGCTGAGGTAGGTGTGAATTGGTTGCTTACGCTTGGTTCTAATTCTTACCATTGTTCATTTTTCCCTAGGGAGTGCAATAAAAGTCTTGGATAACAAGAACTTCCTGATCCTGTGCGAATATTATCCAAAATATATTTCATATCCCATCAAGCCAAATACAAATTATACAAACCTAAGTGTTAGTTGTAGAGGCAACTCACCCGTAAGCTACACGCAAGTTACTATTAGTTCAATAACTACATCCCAGTTATTATTAGATGAACCCCTACCTATACCTCTTGTGTTAGTTTACCCACTGCTCCATTACCATTACAGTAAGCCCAAATGTCAGACTCCTTCTTTGTTTATCAGAAGCATTATACTCCCACCAATTGCTGAGAATGTACTTGGTACTTGGACTTATAATTAGAAGCGCCCCTTGGACTTATTCATATCTACTTTGGTGTAGGTTTGTTGCGTGTTCGCAGATGTTTTATCACCATATTTGCTTTTTTTGTGCAACAAAGCCTTATACTACTTATCTGTAGCGTTAAATGTGAAATAATTTTCTCAATTTACTTAGAGCGTTAAAGTTTTAAATTTTTAACATCTTACTTCCAAACTTGGGGTCATGACTGTTTCAAATAGCAATAAGTTAGAGACTTTCAGATTCTGTAGCTGGGCCGGAATACGAAAAACAGGAAAATACAACTAAATTTATTCATATTTAGAGTATAATTTTAATTTTTACCTGAGTGTAATTTCTAACGAAAGCAAATCATATTAATAAAATTTATTAATAGGCTCAAATAATTGTGGGATAGCTTCGATAATTTTTTATTTTTGTAAGTTGGGAAATTTCTTCTGGCAGTCCATCTAGCTATCGGTGCTTTGAAATTTTTGACACCGAAAATCCTTAATAACCTACCCATCCCCCTCAAGACTTGTCTGTCTTTTAAGAGAGAGAATGAAACAGCCCTGCCGAGGGGTAAGGGGGAGGTAAGGAGGTTAACTTCTGTAAAACAGTACAACAATTTTAACCAGGTGGAGTTATCCCCTGTTTAAACAACCTTTGCTTCACAATGCTAATGCTTAAAAGCCATATTGTGCATTTAACTTACTCAAAGCTTGTACCCTGAACCTACACAAGCATTACCGCACCCATTAAAGTGACGGCTGTTACCAACTCTGCCTTGTTATTTGATAACAAGACGCTTATGGTTGATACTTTGGAGTATTTTGCCTGCTCGCACATAGCACTATAACAACAAGAATATCCATTTTTTGATATTTTTTAACTTACCAGTAGCCATCAAAACAGATGGCTTTTAGTTCTTCATTGGGCAAGAGTGTTCCTTATCAAATAAGTTACTAGTTATACAAATTATGATTTCACTTTTTAGCAGTTCTCAAGTAATTGACCAAATTTATTGGAAAAACTTTTTTGAACTACATAATTACATATCAGTAATTTTAAAAAGGTTTGTGTTTTGGTTTTTAGGTAAATATTTTTCCTCATAGGGTGATGACTACTTCTTATTTATCCCACTAGGAAATTGATCTATCTGAGCTACACCATAGAATGTAACTTCATTTCTTCCTACTCGTAGTCTATCTACTCGCAATTGAGTATTTTCTAATGCAAATTTATCTAAATCTAGTAAATTATTAACATGATTAACTAGAGATTTACTTAGGTCTACTGATTCTTGATTACCACTATATTTGACATTAACAAATTTTATTTTACGTCGCTTCTCCGCTTCAATATTAGCAGTAAAATCAACGTCTATAGGTTTATCTGAGGTTCCCACCCTAATTTGAGTTTTAATTCTGAGAGCTCTATCTTCTGTTATATTCATTTGAGTATTTTGAAAATGTAGGGGTTGTCCATCATAATTAAGCCTTTGGAGTTTCTCTAACACAAATGGAGTATTGAAAGAAGTAGTCAAATCTGACTCGGTTAATACTGTTCTCAGAGTTGCCTGGATGGGCTGCCTTAGTTTGACTTTACCTGTAAAAATTGCACTGAAGTCTATTGATACAGCTTGCAGGTAAAGTTCCATGACTTCGATGCGAAGGCCATTATACATCTGCATTCCTTTACCTATAAAGTCAAACCCATCCAGACTACCCTGTAATAATTTGGCCACTGGTTCTGCCCGAACATTGGCTTCGACTTGATCCGAGCTCTTAAACAGTGCTGCTATTGCAGCTCCTGCCACTTTGCTCACTAGGCGATCGCCTTTTTGATTCAGTATTGGTGTACTGGTAAACAATGCCGTCACCATAATTTTTTAATCTGCTTTTACTATTATAACCTTTTTGTGAATAATTGTAAATTTAACTTGTACTTATGCACTTTATAAGTTTAACTTTTGGCTTAATCAAGAGATGTACCTTCAAAAACGAGAAAATCAAACTTTTAAATGCATAAGTCCTCTCCTTGGAGACACAGCGGTTTCAAAAAGCAATAAATTAGAGATTTTCGGATTCCGCAGCCAGGCCAGACATGAAAAAGAGGAAAATACAACTAAATTTACTGACATTTGGAGTATAACTGTAATTTAAACCTAAGTGTAATTTCTGATGAGAGCAGCTTATATCAATGAAAATTGATTCATGGACTAGATTATGGCATAAATTTGGTGATTTTTCGTTTTTGCGCTTTTAGGAAATTTTCCCATCTTCTACTTTTCCCCCTGGACTCCATCTCCCCAGATGTCTTTTAAGAAAAATATTACAGCCCTAACTCTTTCGAAGGGGTAAGGGTGGGTTGAATTTTAACTTAATCAAGAGGTGTACCTTTAACACAAGCATCTGTTAGTAATGTCCCAGTCAAGTCAGCTTGTTCTACTGAAGCACATAGCAAATTAGAGCTTTGTAAGTTTGTGCCCCTAAGTACTGCTCCACTTAGATTAGCCTCTTCTAAATCTGCACTAGATAAATCTGCGCCAGAAAGATTGGCATTGCTCAATTCTGCCCGAAACAAATTTGCTTTACTCAAATTCACTCCTCGTAAGTCAGCCCCACGAAAATCAATGCCACTCAGGTCCAAATTATTAAATATAGCTCCATTTAAGAAAGCTCCTGCAAAGCTAGCTTCCCTGAGTTGAGCATCAATCAAAATAGCACCCCGTAGGTCTGCATTGCGAAAGTCTGCTCCTCTTAAGTCAGCACCAGTAAAGTCAGCACCTCTAAGATTAGCCCTCAGTTTTGCTTTCTGTAAATTAGCACCAGCAAAATTAACCCCAGGCAAGTAAGCTTGGTAGAAATCTGCTTCTGGGAGCATGGCCCCTGTTAAATCTGTACCTGGAAGATGAGCATTTGCCAAAAGTTTAATCTTGCCAATTCTAATGGCTGAAATGTCAAGAGATAATGATTTATTCATGGTTATTTTCATTTCGTTATTAGGCAGATTAATTTGGGGATGGATAAAAACCCATACCTTTTAGGTGGGGGATACGCAAACTCCCAAATATAAAGATAAGTAACATAAGATTGCCTAAATTTTACAATTAACTTTTTAAAATTAAAATAATTTTATTAAAGTATAGTTAAATATTATACTCAAGAATAAAGTTATATAGTCTTATTAGTTAAAATTATATAGAACTTATGTAAAATAATATATTTCTCTTATTATAAGGAAGGGCTACGGGTCGCAGTCTATCAGGACAGTAATTTCAGGACAATACTTTCGCAGTAGATTGGTAAGTCCTAATTAAAACTACCTAATATTTACAATATCACCAACACAGTTTTTAAATAAGAAGTTGCAATGACGCGACTTTAAAATAATCAGTGATGGTATGTTTGATAGTGTTTTTTTAGTAAATCCTCGCCAAAATCACCATCGAACTCACGCCAGACTGTGTGAACATGGGGAGCATCAATATTTGTGTCTACAAAATTGTCATACTCAATTAAATGGTTCGTGGTACAAAGTCGGTAATAGTGTGGTTTTCCCTTTTCCAATGAGCCTACCCAAACAAAGACCAGTGTCTCAATTTCTGTCAGTGGTGAATTGTCCAGATTTTTGATCAGCTCAGGGCGAAATTTATCAATATAGACTTTAATCAGATCTTTGATTTTCTCTTGTTGAGTTAAATTCATTTCACTGTATTTCAGACCTTTGCGAGGATCTAAAATATTTGTGTCTACTTTCGTCAAATCAGAAATTTTAGAAAAGATCTCTTTTGGAGGCGCTTCTTGGATAAAGGCTTTTTTTAATTGATCATCTGTAAGGGATTCTGCAATTTCTTTGACTAGATTTTCTTCATCTTTTAGAACCATTAGACTATCTTTAAGAACCTGAAAACCTTTGTATTCTCCTTTCAAAACCACAGTTGGGACTGCCCCATAAAAAGTTGGTGTAACAGATAAGAGATGGCCATTTACCAGAGTAATATTAATGGAAATGTGATGACCTTCAAAACTCCAAGCCCAGGTTTTATCCTTTGAAGGAGTTCCGAAAATAGAGACATAGTAGAGTTCTGGGTCAAAGAAAGGCTTTTTTGGGTTCAAAGAAAATATAACCTTTTCAAGCATCCTGACATTTTCCGTCGTGAGAATACCTTTTGCACTTAAAGCTGTTTCAAGAAGGTTCACAACCAGCTTTTTTTGATTTGAATTCATCTGTTTCATCGCCAAACCAAAGCGCTTTTTATCAGGGCTGCTTAAGGGAAGGAAATAGTCGGGAAGGTAAGCCCAGTCATTCCTGTTTTCGTGAGAAAATTCTGCAAAGGCCTGAGATTTTTGATCTCGAGTGAGTGAACCAAGAAAACTATTAGCCGCTTTTATCATGTTACTTCCCGAATAACTTAGCATGGAATCAGTCTCAGAGTATAGAGTCCGATCTTTTTGCTTTGAATTCATCTGTTCCATAACTAAACCAAGGCGCTTTTTTTCAGACTTGACGGACTTATCGGGGAGAAAATCCGAGCCATTCCTTTTTTTGTGAGAAAACGGTGCAAGAGGTTTAGATTTTTGCTCTGCACTCAGTAAATCAAGAAAGGCTACTAATGCTTTTTTGATTTCATTTCCCGGATTATTCGAGCATGAGACAAGGCTCAATACTAATAAGATCATGACAAATAATTTGTTCAATTGTCCCATTTATAACTCCTTCTTTACAATCTGAAAAATGATTTTCTATCAGTAAAAAAATACCATAAGTCTATCCCACTAATAAAATTTGAGAGCAGAAAAGCAACTGGAATACTCCAAGATTCAACGGGGGGCTGTGACAGTAATGCTTGAATAAATTTATTGGGTAAAAATAATTTTTTTGTTGAAAAAAACATGAGATGATAAATGAAAAACACTTTATAAATTGGTCGAACTAGTATCAATGCCGACCCCTATGTGGAGATTGCCCTGCTTCAACTGAAGAAGCTAGAAATATTATTCGTCAAGCAGTAGAACCGAAAACAAAAATCAGAGTATTTGGTTCAGGACATTCTCCCAGCGATATTACCATGAGTAATTACGATTTGATTTGTAGCGATCGCTTGAATCAGATTCTAAATATTAACTGGGACAGTAAAACTATTGTAACTCAGGCAGGAGTTACCCTAAAAGAGTTGAGTTAAGGCCTAGGCCAACATGGACTAGCTTTGCCCAATCTAGGTTCGATTTCCGATCAAACTGTAGGAGGTGCAATAGCAACAGCAACTCATGGTACAGGATTAAATTATGGGATACTCTCAACAATTATTCAGGAAATTACACTAGTAATAGGTTTAGGAGAAGTTATCAAAATCTCCAAAGATGAAAATTCTCAACTATTTAATGCGGCAAAATGCCGTCAGGGAAGTTTCGGATAAGTTATAGAAACCCTGAGTGTATCTTTAAAAAATTAGGCGATATAGCTACCGCCACCATCCTCTGCCAACGCTAATCTCTTGAGCATTAGTCGAATAGAACAAAGATTAATCTTGGCAGTAGCATTTTTCAGAGTTCCCATCAATTTTTTTGCTCAAGCTTTTACATCTCTCCATCCAAGAGTTAGCTCTCTCAATTACCCACCTTGCTTTGACTGGGACAAATCCTGTTTTCCCTTCCTGTTTTTTCTCTGCTTTTGATGGTTTTGGTGATAGTTTCAAGGGAATTTTGGTCCGTAACCCTGGATAAATTTTCTTTAACTCTTCTATTATCTTTTCGGGATGATATCCATGATCAAGTAAGATTGTAATTTTAGGAATGTTGACTGGTTTGGATTTAAAATAGTCAATATTGTCTGACAACATTTCTATTAATCCTGCATCATCAGATACTGATGCCTTAGTACAATGGGTGAAAAAAGGAAAACCAAGACTATCTACTGCTAGGTGTCTTTTGATACCGTTAGTAGCTTTGTAAAGACAAAATCCCTTGGACTTGACACCAGCATTACAAGTGTTTTTTACTGCCTGTGAATCAATGATTATTAAAGTTGTCCCGGAGCGCTTTTTTTTTACCTGTTGACGTACTTGAGAATGTAATACATCTCTAATTTTCTCAATTACCCCTGATTCTCGCCATTGTTTATAATGCCAAAATACTGTTGAATAAGGTGGTAAATCTTTATTGTATCACACCAATTACAACCATTTTTTAATTGATACAAAATACCATCTAAGATTTCTCTGTTGCTCCATTTTGTGGGACAAGTTTTCTTCTTATTTGGTATGGGATGGTTCAATCAGAACCCATTCTTTATCTGTTAAACTGCTTGAATATGGCATTTGCCTAACTCTTGTTTCGGATAATTGGCGATCGCTCTCTAGTATAACATTGGAGGAAAAAGATACACTCAGAGGTTCTATAGAACTCAAATTACGAACAACGAAAGAATTTGACCTAGAAGTACAAGAACAGCCAGGAACTCTAGAAAATGTATTAGATACATTACTAAAACGCTTACAAGCTGACCACTATCGTTTTTGGTATTTACCCCATGTAGATAGGGTATGGGAGTGGAGTGCAACTCGCAAACCACCAGGAAAAAATACTCCCAGACAAAACTTTTTCCAACGCCTCCAGAGTTGGTATCAAGAAAAACTCATTGGCTATTATACATTTGAACGGCTTTGTTGCACAAAGCAAGGAAAGATGGTAAAAATAACAGTGGGTAGCACCAAATCCTGCATTAACTCTCCTTATGAGTAAGTCCAAGTCCAAGTACCGGGTTAGCAACTGGTCGTATGGATGATGCCTCCTTAAAGCAGAGAGGGAGCCTGACATTTTGGCTAAGTTATGAAGTGATAGAACAGTGGGTAAATCAACATCAAACTGGGGGTCAGGGAGCATCGAATACCTATAGCGATGTAGCTATTGAACTAATGGTCACTCTCAGTAGTTTGTTTGCAGGGCGGGGCGACAGACAGAAGGATTTGTAGAATCTATATTTGATTTTTAGAGATTAGATTTACCTGTACCAGACCATAGCACTGTATGCCGTAGGGTCAGAAAACTAAATATCGGGATACCAGTGAGACCAAGGACAGAAGAGATGCATTTGGTAGTTGATTCTACAGGGGTCAAAGTCTACGGTGAAGGGGAATGGAAAACCAGGATTCATGGTGTAGGTAAACGTAGGACATGGCGTAAATTACTAGAGTGCGAATGAGGCCACCGGAGAGATTGTCACAGCAGTTGTCACAACCAATGATGTGAGTGACGACCAAGTATTTTCTGACCTATTAGATGGAGTAGAAGGTGAAATAGCCCAAGTTTCAGGTGATGGGGCTGATGACAAATACAAGTGTTATGAAACAGCTCACCAAAGAGGCATAAAAACGACCATTCCACCGCGTAAAAATGCTGTGATTAGGCAGCATGGCAACTGTAAAGCCCTACCCGCTCCCAGAGATGAGAACCTCAGAGGAATTCGTCAAATAGGACGGCAAAAATGGAAGCATGAAAGTGGATACCATAGACGCTCTCTATCTGGAACCACTATGTTTAGGTTCAAAGTTTTATTTGGTGGGAAGTTACGAAGACGATAATTTGATAATCAAGCAGTGGAGTTATTCATTAGACATCTCCAAAAATACCCACTTCCCTTACTGTGACTATTTTTCAAGGAATTAGCGCCTAATCCCCCAGATAGTCATTTTTTACATACTTTATGGTGTTAGAGATAGTTACTGTTTATTATTCACCATATTGAGCTGTTGTTTTTGTTATCTTCTTTTCTACATATATAGCAATCCCATATTGGTCGCAACAGATATAATAGTAAGAATAACAGATCTAAGAAAAAGACAAAAAATGAATATTATAGATAAACTAAATGATTTTATTAATCAAACAAAAGAGTCTAAAGAAATTAAAAGGGCCTTGGCCGTAAAAATGACCTTGTCAGGAAAATCCTACCATGAAGTCAAAGAATTATTAAATGTTTCTCACAGTTTTATTAGTGAATGGAAAAACCAAGCATTATTTCATGGTGTAGAAAGTTTAAGGCTTCAGTATCAAGGGAGACAAGGTTACTTAAAAACGGTCGAAAAAGAGAAAACAATTGAGTGGTTGAGAGCACAAGATTATCTTAGGTTATCAGATTTAAAAAACTACTTACAGGAGCAATATGATGTGGTTTTTGAGTCTAATCAAAGTTACTATAACTTGTTTAAAGAAGCGGGCATAAGTTGGAAAAAAACTCAAAAAAAGAATCCTGCTAAAAATGATGAATTAGTAGAAGTTAAAAGAAAAGAAATAGAGGAATTTTTAGCTAAATGGCAACCAGAAATAGAAACTGGAAAGCTTACAGTGTTTATGATTGATGAATGTCATCTTCTATGGGGAGACATATTAGGTTATGCTTGGGGAAAAACAGATGAAAGAATAGAAATTGCAATTAAAAATGAAAAAGAAAGACAGACTTATTATGGAGCTTTAGACTATAAAACCAAGGAATTTCTTGTGCAAGAATATGAGAGTGGAAATACTAAAAATACTATTGAATTTATTAAATATTTGCAGAAGCAAAGACCGGGCAACAAATTGGCAATATTTTGGGATGGGGCAACTTACCATAACTCTCAAGAATTTCGAGAATATTTAATGACAATTAATCAATACTTATCAGAAGAAGAATTGTTGATAAATTGTACAAGATTTGCTCCCAATGCTCCGGAGCAAAATCCTGTTGAAGATATTTGGTTACAAACCAAAAATTTCAGTATTACTTTTTATCATCTTTGCAGTTCTTTTAAAGTAGTTAAGTGGCTATTTAAGTTTTTTGCGGATGGTCAAATATTCAATTTCCCAAAACTTTTTCAGTATGAAATTTTGCCGCAACCTACTTAG

Protein sequences of DBSCAN-SWA_10

>NC_008312|6564357:6616950|6585835_6586105_+|WP_011613595.1|transposase|DBSCAN-SWA
MPCVLIIGLSIIPIPELNPHSLLIMDNAPFHQKKEIRALAALDGHSVLFLGPYSPDFNKIEEDLAILKKQRIYAPPETTLDDIVRLYGT
>NC_008312|6564357:6616950|6599354_6599810_+|WP_011613603.1|DBSCAN-SWA
MKRSLHCNFITTYTGTPKFKSADHILTKVNNMTRANKLIGLSPLFDQRIVELSLEILPKYKLSGADEKAVLKQAVADLLPEKILTRPKSGMMVPVNFWFRKIWQRRTKNLLLSKKAAIAPYINQDLIKDWLNYQGDTWRRYGIKLWLLVSL
>NC_008312|6564357:6616950|6567504_6567687_+|WP_044136960.1|DBSCAN-SWA
MVQPLWSIYLKIAVNIVRLDGENDAEIKKQFNIARANNKELFSVDDFNNGDIKALPASTY
>NC_008312|6564357:6616950|6615281_6615647_+|WP_155994539.1|transposase|DBSCAN-SWA
MVTAVVTTNDVSDDQVFSDLLDGVEGEIAQVSGDGADDKYKCYETAHQRGIKTTIPPRKNAVIRQHGNCKALPAPRDENLRGIRQIGRQKWKHESGYHRRSLSGTTMFRFKVLFGGKLRRR
>NC_008312|6564357:6616950|6605913_6606933_+|WP_011613608.1|tRNA|DBSCAN-SWA
MAKSLKPEAFFQAPGVILDVRSPAEYTQGHIPGAVSFPLFNNEERALVGTCYKQKGKDEAVELGLAIAGPKLADFVAYAKILAPDRQVRIHCWRGGMRSASVGWLLETAGFNVALLMGGYKGFRRWALSLFLVPQKIIVLGGMTGSGKTEILHALRDMGEQVLDLEALANHRGSSFGALGQLPQPTNEQFWNKIAMEWGKFDSTQPLWVEAESRSIGLCRIPQEIFEQMEKAIVIEISRSRQERVAFLVEIYGDANIDDLIAATERIRKRLGGLRAQKAIDFGREGNLVAASDLILHYYDKTYTYDLEKRGGYIYKVNVSGLSNLDAAVLVQQKSQEIQ
>NC_008312|6564357:6616950|6576467_6576644_-|WP_155994533.1|DBSCAN-SWA
MNKISTNICNVYQLLITYISVRLHLTLLEYHQQVLEVVGDETWQLSSSYDYKFLGSSR
>NC_008312|6564357:6616950|6567276_6567387_+|WP_081432459.1|DBSCAN-SWA
MDNLKVHHAERVRVAIESVGAQVKFLPPYSPDLSQV
>NC_008312|6564357:6616950|6572951_6573350_+|WP_044136965.1|DBSCAN-SWA
MNTEPIKCNVLTEDDLDPQAGFVFSVEEYNKVFNVTFDCKKVTLEVDGAIRNATLESYKLVNETEVFTHRRELFISNSKEPATHVVELYEGAIYRVGSCMFSCEEILIEPEPINIYIYYTDEELYNKRKSNE
>NC_008312|6564357:6616950|6591182_6591434_-|WP_011613600.1|DBSCAN-SWA
MSEITINLPEEIFSARRLAPEEFVRDMRLAAAIYWYQKGEISQEKAAQVAGLNRRDFLASLAREKIDVFNVDFNDLQRELERG
>NC_008312|6564357:6616950|6583704_6584580_+|WP_011613594.1|DBSCAN-SWA
MSAGKKLRQILEQPGALVLPGVYDCIGAKIVEQIGFPVVFTSGFGISGSTLGRPDYGFITATEMLYAIRRITESVNIPLVADIDTGYGNPLNVIRTVTDIVNMGVAGIILEDQEWPKKCGHFQGKRVIPMAEHVEKIKAAVHARGDSGLVIIARTDARAPLGLDEAIKRGRACAEAGADVVFIEAPQSLEDLQAIATAFEDVYLFANMIEGGKTPVLSGQELAEMGFKIVVYPLSGLFSATQAMINCYRQLFENGTTAGLQDIVSFQDFENIIEVPKYQELEQKFSVDVRH
>NC_008312|6564357:6616950|6571455_6571917_+|WP_044136963.1|DBSCAN-SWA
MPVELTKPWNIDEIHYCWIEWLIETPYTEPAVDFDNDEKSRVIEKIFLGIPIGPITVAPFSTKDCNKIIVDGAKRVKAIKDFCANNLKMSGLQALFSLNGATYLDLSEEQRFEFKCSIIHIVKLEEHDEDAINYVCSSNPGNSHWLKHGAPHE
>NC_008312|6564357:6616950|6590704_6591190_-|WP_011613599.1|DBSCAN-SWA
MAEFPAVNTSPLIFLTQANLLNFLQMLSPKIIVPQAVATEIQAYGNTDVTAQMLAQTDWLVVTQTPAIPAVIQSWDLGAGESEVLSWGYHHPNTEVIIDDLAARRCAQALGIPVRGTLGLVLTAKQRGVISEARPVLEQLRLSGMYLSERLMNQVLMSVGE
>NC_008312|6564357:6616950|6614843_6615038_+|WP_063823353.1|DBSCAN-SWA
MDDASLKQRGSLTFWLSYEVIEQWVNQHQTGGQGASNTYSDVAIELMVTLSSLFAGRGDRQKDL
>NC_008312|6564357:6616950|6610444_6611059_-|WP_011613610.1|DBSCAN-SWA
MKITMNKSLSLDISAIRIGKIKLLANAHLPGTDLTGAMLPEADFYQAYLPGVNFAGANLQKAKLRANLRGADFTGADLRGADFRNADLRGAILIDAQLREASFAGAFLNGAIFNNLDLSGIDFRGADLRGVNLSKANLFRAELSNANLSGADLSSADLEEANLSGAVLRGTNLQSSNLLCASVEQADLTGTLLTDACVKGTPLD
>NC_008312|6564357:6616950|6609185_6609947_-|WP_011613609.1|DBSCAN-SWA
MVTALFTSTPILNQKGDRLVSKVAGAAIAALFKSSDQVEANVRAEPVAKLLQGSLDGFDFIGKGMQMYNGLRIEVMELYLQAVSIDFSAIFTGKVKLRQPIQATLRTVLTESDLTTSFNTPFVLEKLQRLNYDGQPLHFQNTQMNITEDRALRIKTQIRVGTSDKPIDVDFTANIEAEKRRKIKFVNVKYSGNQESVDLSKSLVNHVNNLLDLDKFALENTQLRVDRLRVGRNEVTFYGVAQIDQFPSGINKK
>NC_008312|6564357:6616950|6601515_6602184_-|WP_011613605.1|DBSCAN-SWA
MSKFKRQKKFSLEGKVQEVTIKDGYKLKYVHVETLAGNNYVVKVAKHLRRNFSSVLTPGLEVKIKGEMALCKKTGEEELKAFKITPDFTAKATEIWPSQPVALLEKSSSQLTEMKLPDTEEISSKSQKTTEGNAKCVGKKAEILVCQKSDCEKRGASKICKALSKALSEHDLQDQVKIKKTGCLKKCKAGPNIIVMPQKAKYSRIRSAEIPQVIQKHFVLKA
>NC_008312|6564357:6616950|6586110_6586902_+|WP_011613596.1|DBSCAN-SWA
MTIDIKPAPTAPDGEIMMIKENHFLDIFDSADMSLSFFGICIKNAPLLIFAIRLLTAGYPARIKDRNLGAKLLNKVKEVVRGNYDVNTFLSQVDNWFNFQANSINRLPEKVQNQRLTELRDYRDCLVAFFAKFQPKSLNDWKTEIDKIFDESTTTKKIIDLYTIHSGKGGEGHYTFIIYPENMPIEFEKQSTEERQQEQHMIYVALTRCLTRAKGGILWLVLEGKKDTVNYPKWLPHDYRKLWKDDKGEYFELDFEELEDIEF
>NC_008312|6564357:6616950|6590116_6590695_-|WP_011613598.1|DBSCAN-SWA
MQTNLAEKWRSAFWQVVQQPTHAQTLQTAGEQKQLKEWTSALTAVVVSTCQTLGWQASAKGYSLELLPVATNEFLTMDVMAFVGAAQRWQFPIAVIELENNWERSAYSLWKVLCVRVALRVVFCYCQTAGERRELINYLEREILQPILPRERLDLQGETLVVVGSREAALTFPYDFFKWWLMEVNIGKFTLF
>NC_008312|6564357:6616950|6591533_6594539_-|WP_011613601.1|DBSCAN-SWA
MTNYPKRLIEVDLPIKQISAHARREKSIRHGHISTLHIWWARRPLAACRAVICAALWLDPVDDNCPELFRVEAAKVINGFAKIVDKNLDNHGSTANLKKWQVLAKPKNQLNPEKIEHLNILRYRLLDFIADFANWDNSTHPDYLQTSRKLTEISHYSLGGITDTKPVVFDSFAGGGAIPLEALRVGADAFASDLNPVAVLLNKVVLEYIPKYGQTLADEVRKWGEWIKQEAEKELGEFYPKSAATLKNGDVETPIAYLWARTIVCEGPGCGAEVPLMRSLWLAKKKNRSVALRLIPRQEEKRVDFEIVEQVKGKDVGDGTVKRGSATCPCCGFTTPVASVRKQLQARGGGADDARLFCVVTTREKVKGRFYRLPNERDLEAVRMAGEELARRKLEYGGELSLVPDEPVPVMSGVFNAPIYGHNTWGSLFSSRQALALTTLVRLVKEVGKKLASNEDERLAIAIQTCLALAVDRCTNQFCSLSKWNNSRELIDGVFARQALPMLWDFGETNLVGGSDGYWQGAVSWVLSVIKASLLPDPGQTQQANAASHPLPDDFTQCFFSDPPYYNAVPYADLSDFFYVWLKRTLNKTYPNLFSSETTPKDDEICEMAGWDSKRYPHKNGKWFETQMAKAMAEGCRIISSDGIGIIVFAHKSTAGWEAQLQAMIDAGWKITASWAIDTERGNRPRAQNSAALASSIHLVCRPRNNNNIGDWRDIIQELPQRIQDWMPRLTSEGIVGADAIFACIGPALEIFSRYSSVEKVNGQPVTLGEYLEYLWGTVANEALKQIFSEADTNNLEADARLTVIWLWTLSTGSTESATETESDQDEEDTPASKNQKSTGFALEFDTARKIAQGLGAHLENLTHLVEIKGNKARLLPVQERSHYLIGKVAPTTNTKKRKSKTPKQLSLEGILPEKETEIEVEADIAIAEIGKTVLDRIHQTMLLHKTGRSEAVKRLLVEEGVGKDPRFWNLADALLRVYPQNVEEKRWLEGILARKKGLGF
>NC_008312|6564357:6616950|6577621_6579505_+|WP_011613590.1|DBSCAN-SWA
MEKKSKRDRGRIITTSGLKKLNEAIEEWKQKYNLRGTLAEIEAESGVGSDTISKIRQGRVGADLSKIQQLFAAFDLTLDETDYRSGKQSSSEMDSEPLSQLLPLLNDEQIVTKNSFQIFISYNRQDPDQELARQFETALAAAGHQVFMAGDHIRLGENWFRRINIELKRCDYLLLFLPPQSAQSELLTYQVQLARELQFSRPERKPVILPIRVGFSLTQPLNHDLRGYLYRIQQREWRSPEDTIIILKEVLTLLAAPPGNIALEIEEKKEISLSEEISSIASANFPPLPSAEPEIPGGQIDVASNFYIERPPIEERCYQTILQPSSLIRIKAPRQMGKTSLMARILHHAAFQGYRTIPLSFQLVDKEVFSNLEKFLKWFCAYVGRELRLPNQLDDYWDDIFGSKVNCKDYFEKYLLAQIDHPLVLGLDEIDRVFQYPDIAEDFLGLLRAWHEESKRRAIWKKLRLLVVHSTEVYIPMNINQSPFNVGLPIDLPEFNLPQVKDLAFRHNLNWSEQEVEKLMAIIGGHPYLVRVALYHISKQDLTLEDLPENVMSETGIYSDHLRRHLWNLEEYPELVAAMKNIISENLNERLTGILGFKLDSLGLVKWQGNKYHPRCELYRQYFQVHL
>NC_008312|6564357:6616950|6615912_6616950_+|WP_011610086.1|transposase|DBSCAN-SWA
MNIIDKLNDFINQTKESKEIKRALAVKMTLSGKSYHEVKELLNVSHSFISEWKNQALFHGVESLRLQYQGRQGYLKTVEKEKTIEWLRAQDYLRLSDLKNYLQEQYDVVFESNQSYYNLFKEAGISWKKTQKKNPAKNDELVEVKRKEIEEFLAKWQPEIETGKLTVFMIDECHLLWGDILGYAWGKTDERIEIAIKNEKERQTYYGALDYKTKEFLVQEYESGNTKNTIEFIKYLQKQRPGNKLAIFWDGATYHNSQEFREYLMTINQYLSEEELLINCTRFAPNAPEQNPVEDIWLQTKNFSITFYHLCSSFKVVKWLFKFFADGQIFNFPKLFQYEILPQPT
>NC_008312|6564357:6616950|6573763_6574108_+|WP_044136967.1|DBSCAN-SWA
MSNEMKTYELSVDSSMGWYIKNQVKWMKVSDLTPDDYEELNSNSRLFLIAYKERIFKLTYTLVQEFFKIEKFDDGTLYLWSLSGYKFNKEHRTAYITALEIEDWRVEDIISSYS
>NC_008312|6564357:6616950|6579711_6581169_+|WP_011613591.1|DBSCAN-SWA
MYTETKNSNKNAVIVGGGPAGFATALILAKRGWHQITVLEKRPAADFYEPDKSFNYLIDGRGQKFTDLFSLTEKLAKISVPNTEFYLTEIKANGNRKTSKLPIIDPNRKTAYWLQRPIFLQLLFQEIEENWHNKITTLFNTKCLDINKKDGKLTIIAQEINDQNNYEFEADLLVGCDGINSLVRQTLDKWDNSGTDKFKMQFFPSASSGLKYKVLTLPPNFPLDHNNSEQAVCTMAYAIRGAFSDSQHSLSLGILPFADPNKPRTANIIRRPEHEIWKLQDGEKLSEFFHKAFPQLPINEIVLSEEKERFAKSEGGYFPIPQYCSGLHFLLSNTDNSSGVVLLGDAVHCFPPDIGQGVNSALEDVFILNQALTKTNDIISDTLPLFESLRSPDIKPLIRLAQTAYPWQYNQGILGKRLWSINFFMRFLLSKILPFIFAPPAFILIQNHQLSYREIWRMAQRTTLFIFVLGIVIVLGTIALFLENL
>NC_008312|6564357:6616950|6605232_6605397_+|WP_081432496.1|transposase|DBSCAN-SWA
MIAGRFYPSSQICSHCGYKQKMLLHKRTYECDNCGLKADRDFNAAIKSKNYVNK
>NC_008312|6564357:6616950|6586957_6590008_-|WP_155994535.1|DBSCAN-SWA
MMAIKAWYKIDGLIPREDLREGKPLDTSEFAIHLDQVRNNNAPVDYQQPERFFERTYLTKSLTDLASQVVRRLSGETSGTSAIFNLSTQFGGGKTHALTLLYHLAKNGSLANNWTGVDKILKTAKINSIPEAAVAVFVGVQFDSITGRGGNDGTPLRKTPWGEIAFQLGGETAFNYVAEHEKNFIEPKGDVIRKLFPKDRPCLILMDEIINYISTYRSREYHNRFYNFLQALSETARSLENVVLVVSIPASEMEYTQADEADEQRLKKMLDRLGKAIVMSAESETSEIIRRRLFEWDKEAVTTEGKIMLPRDAIATCNEYAEWVISHHQQIPSWFNVDNAQKAFIATYPFHPTVLSVFERKWQVLPRFQRTRGILRLLALWVARAYQESYRKVHNDPLIGLGNAPLDDPLFRTAVFNQLGEERLEGAVTTDICGKQNAHAIRLDKEAVATIKKSRLHRKVATTIFFESNGGQQNTEATIPEIRLAVGEPNFDIVNVETVLEALQNESYYLLVNKNRYRFNISPNLNKILADRRANIQSSRIQERVAAEIKKVFTTNGVIQVVYFPEYTNSIANRPVLNLAILSPEYVRSDEETSKFIESIILNCGSSARTFKSAIIFVVANPDNLLRERARNLLAWEDISDQETELNAEQKQQLKENIDKSKKLLQETVWQSYTSVALWGKNPEIPEIQEIQWIDLGMLNSSQANSMVSLIINRLQANGEITSVIHPRFLLRNWPPVFTEWSIKNIQDAFFASPTFPRLLEAKAVPEAIVHGVREGLLAYVGKSKNGYEPFIFNQPNFSVQDVEISDDVFVIKAEVAEDYEARIKDPPRLTQLIISPEEVLLKPGQKQTFLVTGKDQYNRSINVEEINWSATGGEINFNGVLTAGKDEGNFIVTAQVEYISIKAKFTVELKLPHLQEKSENYNITDSSLTKSDRTNEITEGETSNIPNIISWRGEITPQKWMQFYTKVLSRFAAKKDFNLTVEINFSVTGSITSQNINETKVSLQELGLDDGIETS
>NC_008312|6564357:6616950|6614340_6614808_+|WP_155994722.1|DBSCAN-SWA
MRTHSLSVKLLEYGICLTLVSDNWRSLSSITLEEKDTLRGSIELKLRTTKEFDLEVQEQPGTLENVLDTLLKRLQADHYRFWYLPHVDRVWEWSATRKPPGKNTPRQNFFQRLQSWYQEKLIGYYTFERLCCTKQGKMVKITVGSTKSCINSPYE
>NC_008312|6564357:6616950|6569212_6569659_+|WP_155994527.1|DBSCAN-SWA
MANSVKSYKAKGVCVYMRQENPVILGKVFNPDELWQKIGTVNLNRECFSKHITTIYNINNCDSRLRNFISRCLISWKKIIVEKSFGQSSRFSFVAPHQKIIISNVETIISLENRKFLVKPNVIISCFSTSWDIDNYRDIIRTTITGFR
>NC_008312|6564357:6616950|6573342_6573771_+|WP_155994531.1|DBSCAN-SWA
MNNKVYQCNIIIEHERSWEWFQRNENPNGKISYEAGWAFLIDDYREVFDDNFSKTILVSLSGESPNKTKISNYVEGRKRIVTYHTQHLRVCGYEDKVNSIVCFQEGNLEMVGTFEFKFCNESSDWKKINLYVYIPEYYDKNV
>NC_008312|6564357:6616950|6570899_6571466_+|WP_155994529.1|DBSCAN-SWA
MSEFDPEIDLKYIGYLALAYDKKEGKPVSSPNDILVIEQEIRDVSRRINYRNTEIPIENLVSNIIPGFTSEWGIEKKSRVIEDVLLGVPINPIWVVSLDTYDEDRFIKIITGEEVVMALSDFICNKFSLFGMKLIQSSKGVKYQDFSVQMQRKITRSTVRLLELNPRVEGKILAYLRKSNAYGVNNAC
>NC_008312|6564357:6616950|6564786_6565068_+|WP_011613580.1|DBSCAN-SWA
MGKHGDVFAAYADAIEFLSTRKEKIQKVYSFDVDIESLQVEVVEVYPDREKHDWKGHPVTVGYGDFLIGPETTACLYLGYVYMFKKKYLEGQV
>NC_008312|6564357:6616950|6613061_6613250_+|WP_081432497.1|DBSCAN-SWA
MIRQAVEPKTKIRVFGSGHSPSDITMSNYDLICSDRLNQILNINWDSKTIVTQAGVTLKELS
>NC_008312|6564357:6616950|6574336_6575470_+|WP_011613589.1|DBSCAN-SWA
MQDWKTNLLNKIVEKYVNNSNEWVELEFDLNKVLELIIVSNNFYGKSSQERGISVSKYLKTIGADEISKYSTYYTVEESYSINLRKPSRLKYFNPSTWLELAYCAANPQNYTKVERVKRSPSPKVIVFYSYRDSGDKTTSVAITGLKLVEKGYNVALMDLNLESPGLSALINQKELPKKGFVDYFYDKSFGKVDVEVSIDQTFFEVKTKFEWAGGNLFGFYPGELSPDYTCKLEYINPQVVLDDNETLWSVLKKEVYEHLDLDFILIDSASGLSKWAALLLTQAADEALIFTDTSDNSINGTNLILEAIDVLGLKKKIVLSLLEFVNKDKAIENAWEKINFSVKREDEFFVVPHFSLNNYTNINQIYSNIARFIYSN
>NC_008312|6564357:6616950|6566921_6567284_+|WP_052845848.1|DBSCAN-SWA
MQKKSLYASEQDTPRVQELRHDYRRWLDKIDVRNLVFVDEARINLSMSRLFARAVDGERAVGSSIPGSKGGNVSLIGALNLDGLIASMTVPGSTNTEVFITLLNPGLTTSVVARGNRGNG
>NC_008312|6564357:6616950|6568129_6568774_+|WP_011613584.1|DBSCAN-SWA
MTVVGALATAIKQTLSATKLAVEAGEPELVESFWKEMKDIQEGNYDEREKLALPSNKGNNNENNPDGGQGPHTYESLVKLTLKDIKEIAFNLDLSVKQAKEYGSVRQKTSWITAILNKQDDQLAESKPIVTSPPLEKGEDEILDVSSVTLIEESTDNSISETEPKPVSETDTKPTSKLETELINEPINEPINEPINKPETELDDFNDEEEYAGW
>NC_008312|6564357:6616950|6569655_6570324_+|WP_011613585.1|DBSCAN-SWA
MRFDNEEDRKNQKLQISILGFYDEEIRLIKTEESSVIVTNSKETLQSKIKAINAVTPVMKNINNSSYYYTITVLRIDNLNVEFYNIDSYYEVTMAKINETLDIIKRVLYSEISTSIVRYPSGNVIFSSDTCLNNDGSYTITGFDYTNTSAEKYYAVGEYDKMLRYLFKDKFLREYKVLGYLSRELLDPNRTKPLKEVEVYINSKIITFGGFPAAIEEYSIAA
>NC_008312|6564357:6616950|6605574_6605769_+|WP_044136970.1|DBSCAN-SWA
MKSIRSKLKLNNQQKTLMAQHASYNRWSYNWVLNWWNVADKDGYQPLAIKLREVLTSHTKPLEP
>NC_008312|6564357:6616950|6600205_6601207_-|WP_011613604.1|DBSCAN-SWA
MSQTKPTILVSGGAGYIGSHAVQALQNAGYDIVILDNLVYGHRDIVENVLKVEMIVGDTSDRSLLDKIFATHNIAAVMHFAAYIFVGESVKDPQKYYHNNVVGTLTLLEAMLKASIKKFVFSSTAAIYGKPQTIPIPEDHPKNPINPYGASKRMIEQILADFEIAYDFKSVCFRYFNAAGAHPNGLTGEDHNPETHLIPLVLFAALGKRDSISIFGTNYKTPDGTCIRDYIHVCDLADAHVLGLEYLLNGGESNIFNLGNGNGFSVREVIETVKQVTGREFKVEERDRRPGDPPILVGSSEKARKVLGWSPKYPEVKEIVSHAWQWHQKRHGK
>NC_008312|6564357:6616950|6613274_6613484_+|WP_011613612.1|DBSCAN-SWA
MPNLGSISDQTVGGAIATATHGTGLNYGILSTIIQEITLVIGLGEVIKISKDENSQLFNAAKCRQGSFG
>NC_008312|6564357:6616950|6615130_6615268_+|WP_011613615.1|transposase|DBSCAN-SWA
MRPRTEEMHLVVDSTGVKVYGEGEWKTRIHGVGKRRTWRKLLECE
>NC_008312|6564357:6616950|6564357_6564639_-|WP_081432417.1|transposase|DBSCAN-SWA
MNLSWSPLGKCMSKHCTRSPRQRSVGGGLLARLRTLQDKLFDILFYFKCYPTFDLAGILFDIDRSQAHYWVHRLQTMLEAALGEKKARCIASN
>NC_008312|6564357:6616950|6602326_6602572_-|WP_011613606.1|DBSCAN-SWA
MSTFNQKPGICEIVEVSCVDRWQVYRRLQELDIDCWCEPEKPLQVHLKNTNEANQLESVLKQFTAHRYELVQLLQSSWEVS
>NC_008312|6564357:6616950|6582941_6583523_+|WP_011613593.1|DBSCAN-SWA
MTHNKKIEKPKLIIGEGKEDFLFFYSLIKHLKINDIQVDFYNGKNNLNNYFKTLHLKPGFSNLCSLGITRDADQSFDTASQSIDNSIIQNQLNEKKNLTIKKFIFPDNSSSGMLEDLCLRAIDDSDIGCITDFFQCINKNKNIKPTEFSKAKIHAWLSSQVKPDKRLGEAAQAGYIDWNHPNFNPLINFIKSL
>NC_008312|6564357:6616950|6611457_6612774_-|WP_011613611.1|DBSCAN-SWA
MGQLNKLFVMILLVLSLVSCSNNPGNEIKKALVAFLDLLSAEQKSKPLAPFSHKKRNGSDFLPDKSVKSEKKRLGLVMEQMNSKQKDRTLYSETDSMLSYSGSNMIKAANSFLGSLTRDQKSQAFAEFSHENRNDWAYLPDYFLPLSSPDKKRFGLAMKQMNSNQKKLVVNLLETALSAKGILTTENVRMLEKVIFSLNPKKPFFDPELYYVSIFGTPSKDKTWAWSFEGHHISINITLVNGHLLSVTPTFYGAVPTVVLKGEYKGFQVLKDSLMVLKDEENLVKEIAESLTDDQLKKAFIQEAPPKEIFSKISDLTKVDTNILDPRKGLKYSEMNLTQQEKIKDLIKVYIDKFRPELIKNLDNSPLTEIETLVFVWVGSLEKGKPHYYRLCTTNHLIEYDNFVDTNIDAPHVHTVWREFDGDFGEDLLKKHYQTYHH
>NC_008312|6564357:6616950|6571937_6572378_+|WP_011613588.1|DBSCAN-SWA
MTEELINLTWKSVSDINNPDNPKRRGWLIPLDDLDEIKRGTYCNKTVVLKLDNLNPQQIVLSDYMESKDRVKLRETQELTHWGKEYKLRPIIYRKPKNYFPKTEHELPADFLSARGVIKRGEVYVAFIYQTSIKRISTMNLFTVLE
>NC_008312|6564357:6616950|6602855_6603398_+|WP_011613607.1|DBSCAN-SWA
MSNGTTATPVQAFGQIADNPIGLEKSVTEPVCEGMNVALASCQALYLQYEKHHFVVEGAEFNQLHEFFKESYEEVKEHVHEMAERLNGLGGVPVASFAKLAEMCCFTPEEDGSFNARNMIEHDLKAEQDVIKLLRRLAAQAESLGDRATRYLYEKILLETEERAYHLDHFLAPDTLVVLN
>NC_008312|6564357:6616950|6565157_6565502_+|WP_155994525.1|DBSCAN-SWA
MLDCSHKFKFIKAVVEALEQYGDVFAAYVNTINPGLPQTEKEELVYNFSEVAKRLTVKAVKVDKDYPDHDWKDSSVDVVYGDSKISNHLGYTYIFTENPDEATAEKSDEPSLFY
>NC_008312|6564357:6616950|6567740_6568133_+|WP_011613583.1|DBSCAN-SWA
MGIIEQILEERKRFQYKIEHLSIETLAGIYPFYELNHKWLPSQQSKFIEWIFLGLPVNPIYIVSRGGQLDVGYCAETIDGAKRISALKAFVCEDLVLSGLHRLKCLNGVRFKDLPEEEQEQLTSKDIRSN
>NC_008312|6564357:6616950|6572550_6572946_+|WP_044136964.1|DBSCAN-SWA
MKTEPIKCNVIGLYNKGIALLFSKQDYDNLFEGDRLDEALNKGLSLEIDNDVTGARINGYEATEKIAINEHLRWLDVANSEYKILCNVSQQVGNIKLLGKCKLDCNVEMRLPKEMLICVYYSILECEMFEG
>NC_008312|6564357:6616950|6565476_6565929_+|WP_011613582.1|DBSCAN-SWA
MMSLVYFIDMKSENFALNDRANMKVTKSFSQKKLIVVDKVNEQYIVSVVYYKDISDNLISEMENRLTIYADIFAAFINSLPLETPFEEYENITFNFKSVIQKYDVKAVQVDTKHIKSDLGSIFITYIAVGRVSTFGNNCYVFQPILQERM
>NC_008312|6564357:6616950|6581855_6582941_+|WP_011613592.1|DBSCAN-SWA
MFKSLIIKNFRCFQEITIDNIERINLIGGVNNVGKTALLEAILLLNSLNSIEIPFELNFNRGVIQQPTFDIEEICEWLFYQKQIGKSIKIQTIDENGEERELKLSLDKALSPRLFPLSSKTNSRKTIKDLKLELKKAGQKLLGFTAFITIDKEGEIRIEFQQDEKQKIEEIQLFYPIVFHSSRLKVSSTENAKVFSDFALKNEQNEIVEILQIVEPRLKRLEILVTGGIPIIHGDVGGDNLIPVVLMGEGMGRLLSMILSIMNTRGGIVLIDEIENGIHYSAMEKVWQSINIATRKFNTQLFATTHSYECIHAAHRAFSDSESYNFRYFRLEREKETNSIKSLVYDKDNIETSLGLSWEMR
>NC_008312|6564357:6616950|6598910_6599051_+|WP_155994537.1|DBSCAN-SWA
MLRFHALLNVLKKTGKLTIQCDEMWSFIGNKNNKQWLWLAIDIETQ
>NC_008312|6564357:6616950|6585625_6585769_+|WP_081432494.1|DBSCAN-SWA
MERLNNTLRQRISRLVRKTLSFSIKLRSHLGDIWYFINHYNEAIASL
>NC_008312|6564357:6616950|6570408_6570885_+|WP_044136962.1|DBSCAN-SWA
MYQLAEKKATMITDEEVFESINKDFKQNTGFFVSVIKCGTEYLRSVDYENSKLKNRLEFPTNLVKIRVIDSPINIIESNQLANALNIFYFEIDYQTNRYSWEENRERSTENFVKLFEKIDKHLFDTIVKKRANVAFLMSHKVAKISFKTRFFGLITRL
>NC_008312|6564357:6616950|6594821_6598238_-|WP_011613602.1|DBSCAN-SWA
MQITELQPNIIITGSLFSEPVQIITTNHMGESIKLIGKGTQTNQVYDPILTPQQIASLSAITKTKLFDGNSASFRLGVEALRWKLAYEYDPYFSLAIARVDPLPHQLEAVYDYFLKLPRIRFLLADDPGAGKTIMAGLLLKELKIRGLVQRTLIVAPANLTFQWQRELKDKFREDFEVVKGDILRANYGNNPWQEKSQIVTSVSWVSRIQDAKESLLRSNWDLIIVDEAHKMSAYKSDKKTLAYQLGEKLSEMTDHYLLMTATPHKGDPKNFCLFLELLDKDVYGDVRSLEEAMVNNVAPFYLRRTKEALVTFPDPETKEVKKLFPNRKVETIEFQIDDAELDFYDALTRYVEDQSIKASKDNSARGRALGFTMAMLQRRFASSMFAIRRSLERMKEKRQKIIDDPQGYREQKISRHLPNDFEDLTEQEQNKIRESLESVVASVNPGNLQDEIAQLTRLIYLALELEKREIESKLVKLKEIITSKGIFQDRKMKLLIFTEHKDTLDYLVGKLRGWKLSVTQIHGGMKIGDRDTPQTRIYAEREFREDAQILVATEAAGEGINLQFCWLTINYDIPWNPVRLEQRMGRTHRYGQEKDCLIFNFVATNTREGRVLWKLFERIYAIEADLDPENTGKVFNVLGDIFPANQLEKMLRDMYARNISEDGIKDRIVQQVDSKHFQKITNSALEGLAKRELNLSKLIGKSTEAKENRLMPRSIENFFLKAAPIAGIHPKEVKKNSHIYRVGKLPRTLWSVGDRLEPQYGKLGREYKKIIFDKDLLKSDPTLEWVTPGHPLFECVREKVGEIVTEDLQRGAIFYDLHRRKPSYLDVFAAAIVDGRGRKLHERLFVVETRSDGEMIVRQPTVFLDLAVAELSELSEVDMERPRLEWVELALYEKALQPFLAENLAQRQQEVKSILNHTEISLNTIIDRVQCQFAELHAEKEAGSKEAGLDGRIKQMDDRLFELNGRLESRREELEKEASCAISGVHHYGCALVLPHPERSSPELAPMVSDRDIECIAIDKVMEYERGRGWQVESVENQNRGFDLISRKPHPEDIQTAISVRFIEVKGRATVGTVVLTNNEYQTAARLQGDYWLYVVFNCATNSEVYTINNPVKLGWEPLNKIEHYQVEASKIISASQ

Homologous phage analysis in the prophage region

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_081432417.1|6564357_6564639_-|transposase	DDE transposase family protein	NA	NA	NA	NA
WP_011613580.1|6564786_6565068_+	hypothetical protein	NA	NA	NA	NA
WP_155994525.1|6565157_6565502_+	hypothetical protein	NA	NA	NA	NA
WP_011613582.1|6565476_6565929_+	hypothetical protein	NA	NA	NA	NA
WP_052845848.1|6566921_6567284_+	hypothetical protein	NA	NA	NA	NA
WP_081432459.1|6567276_6567387_+	hypothetical protein	NA	NA	NA	NA
WP_044136960.1|6567504_6567687_+	hypothetical protein	NA	NA	NA	NA
WP_011613583.1|6567740_6568133_+	hypothetical protein	NA	NA	NA	NA
WP_011613584.1|6568129_6568774_+	hypothetical protein	NA	NA	NA	NA
WP_155994527.1|6569212_6569659_+	hypothetical protein	NA	NA	NA	NA
WP_011613585.1|6569655_6570324_+	hypothetical protein	NA	NA	NA	NA
WP_044136962.1|6570408_6570885_+	hypothetical protein	NA	NA	NA	NA
WP_155994529.1|6570899_6571466_+	hypothetical protein	NA	NA	NA	NA
WP_044136963.1|6571455_6571917_+	hypothetical protein	NA	NA	NA	NA
WP_011613588.1|6571937_6572378_+	hypothetical protein	NA	NA	NA	NA
WP_044136964.1|6572550_6572946_+	hypothetical protein	NA	NA	NA	NA
WP_044136965.1|6572951_6573350_+	hypothetical protein	NA	NA	NA	NA
WP_155994531.1|6573342_6573771_+	hypothetical protein	NA	NA	NA	NA
WP_044136967.1|6573763_6574108_+	hypothetical protein	NA	NA	NA	NA
WP_011613589.1|6574336_6575470_+	hypothetical protein	NA	NA	NA	NA
WP_155994533.1|6576467_6576644_-	hypothetical protein	NA	NA	NA	NA
WP_011613590.1|6577621_6579505_+	TIR domain-containing protein	NA	NA	NA	NA
WP_011613591.1|6579711_6581169_+	FAD-dependent monooxygenase	NA	NA	NA	NA
WP_011613592.1|6581855_6582941_+	AAA family ATPase	NA	NA	NA	NA
WP_011613593.1|6582941_6583523_+	hypothetical protein	NA	NA	NA	NA
WP_011613594.1|6583704_6584580_+	oxaloacetate decarboxylase	NA	NA	NA	NA
WP_081432494.1|6585625_6585769_+	hypothetical protein	NA	NA	NA	NA
WP_011613595.1|6585835_6586105_+|transposase	transposase	NA	NA	NA	NA
WP_011613596.1|6586110_6586902_+	hypothetical protein	NA	NA	NA	NA
WP_155994535.1|6586957_6590008_-	AAA family ATPase	NA	NA	NA	NA
WP_011613598.1|6590116_6590695_-	hypothetical protein	NA	NA	NA	NA
WP_011613599.1|6590704_6591190_-	DUF3368 domain-containing protein	NA	NA	NA	NA
WP_011613600.1|6591182_6591434_-	UPF0175 family protein	NA	NA	NA	NA
WP_011613601.1|6591533_6594539_-	DUF1156 domain-containing protein	K9MDJ7	Sulfolobus_virus	4.8e-32	25.2
WP_011613602.1|6594821_6598238_-	DUF3883 domain-containing protein	A0A1B1IUI1	uncultured_Mediterranean_phage	5.6e-61	28.0
WP_155994537.1|6598910_6599051_+	hypothetical protein	NA	NA	NA	NA
WP_011613603.1|6599354_6599810_+	asparagine synthase	NA	NA	NA	NA
WP_011613604.1|6600205_6601207_-	UDP-glucose 4-epimerase GalE	A0A2K9L5H6	Tupanvirus	2.1e-56	38.7
WP_011613605.1|6601515_6602184_-	(2Fe-2S) ferredoxin domain-containing protein	NA	NA	NA	NA
WP_011613606.1|6602326_6602572_-	hypothetical protein	NA	NA	NA	NA
WP_011613607.1|6602855_6603398_+	DNA starvation/stationary phase protection protein	NA	NA	NA	NA
WP_081432496.1|6605232_6605397_+|transposase	transposase	NA	NA	NA	NA
WP_044136970.1|6605574_6605769_+	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_011613608.1|6605913_6606933_+|tRNA	tRNA 2-selenouridine(34) synthase MnmH	NA	NA	NA	NA
WP_011613609.1|6609185_6609947_-	DUF2993 domain-containing protein	NA	NA	NA	NA
WP_011613610.1|6610444_6611059_-	pentapeptide repeat-containing protein	NA	NA	NA	NA
WP_011613611.1|6611457_6612774_-	DUF3500 domain-containing protein	NA	NA	NA	NA
WP_081432497.1|6613061_6613250_+	FAD-binding oxidoreductase	NA	NA	NA	NA
WP_011613612.1|6613274_6613484_+	FAD-binding protein	NA	NA	NA	NA
WP_155994722.1|6614340_6614808_+	hypothetical protein	NA	NA	NA	NA
WP_063823353.1|6614843_6615038_+	hypothetical protein	NA	NA	NA	NA
WP_011613615.1|6615130_6615268_+|transposase	transposase	Q9MCT5	Escherichia_phage	9.2e-08	65.8
WP_155994539.1|6615281_6615647_+|transposase	transposase	NA	NA	NA	NA
WP_011610086.1|6615912_6616950_+|transposase	IS630 family transposase	NA	NA	NA	NA

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage
NC_008312.1|WP_011613615.1|6615130_6615268_+|transposase	6615130_6615268_+	45 aa aa	NA	NA	NA	6564357-6616950	yes

Protein sequences of NC_008312.1|WP_011613615.1|6615130_6615268_+|transposase

>NC_008312.1|WP_011613615.1|6615130_6615268_+|transposase
MRPRTEEMHLVVDSTGVKVYGEGEWKTRIHGVGKRRTWRKLLECE

Self-targetings in the prophage

CRISPR ID	CRISPR type	Spacer info	Spacer location	Spacer length	Protospacer location	Mismatch
NC_008312_10	Orphan	10.1|1399212|19|NC_008312|CRISPRCasFinder	1399212-1399230	19	6605857-6605875	2

1. spacer 10.1|1399212|19|NC_008312|CRISPRCasFinder matches to NC_008312 position: 6605857-6605875, mismatch: 2

agaagttaaaagtcaaaag	CRISPR spacer
agaaggtaaaagtcaagag	Protospacer
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