CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NC_008321	Shewanella sp. MR-4, complete genome	2 crisprs	cas3,csa3,DEDDh,DinG,RT,WYL	0	0	4	0

Results visualization

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CRISPR-Cas detection and classification

Crispr_ID: NC_008321_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_008321_1

1825977-1826116

Orphan

Consensus_repeat	Method
AATTTAGGAAGTTGAACCCTAGGGTTCCTCATTCTTAGCGC	CRISPRCasFinder

1 spacers

The CRISPR arrays of NC_008321_1

>merge|NC_008321|1|1825977-1826116|CRISPRCasFinder
AATTTAGGAAGTTGAACCCTAGGGTTCCTCATTCTTAGCGCCGCTCCTCGGCCATATTTCACGAAATGCCATCGGCGATGATGGTTTTTTTGTTTCTGTAATTTAGGAAGTTGAACCCTTGGGTTCCTCATTCTTAGCGC

>NC_008321|1|1|1825977-1826116|CRISPRCasFinder
AATTTAGGAAGTTGAACCCTAGGGTTCCTCATTCTTAGCGC	CGCTCCTCGGCCATATTTCACGAAATGCCATCGGCGATGATGGTTTTTTTGTTTCTGT
AATTTAGGAAGTTGAACCCTTGGGTTCCTCATTCTTAGCGC

Protein	Signature genes	Signature genes Name	Protein_function
NC_008321.1\|WP_011622322.1\|1816671_1818813_+\|bifunctional-23S-rRNA-(guanine(2069)-N(7))-methyltransferase-RlmK/23S-rRNA-(guanine(2445)-N(2))-methyltransferase-RlmL	unknown	unknown	gnl\|CDD\|236981
NC_008321.1\|WP_011622334.1\|1833867_1834698_-\|ABC-transporter-permease-subunit	unknown	unknown	gnl\|CDD\|372253
NC_008321.1\|WP_011622330.1\|1829867_1830416_+\|CDP-diacylglycerol--glycerol-3-phosphate-3-phosphatidyltransferase	unknown	unknown	gnl\|CDD\|182763
NC_008321.1\|WP_011622328.1\|1827236_1827881_+\|UvrY/SirA/GacA-family-response-regulator-transcription-factor	unknown	unknown	gnl\|CDD\|236538
NC_008321.1\|WP_011622331.1\|1831415_1831691_-\|HU-family-DNA-binding-protein	unknown	unknown	gnl\|CDD\|259853
NC_008321.1\|WP_011622336.1\|1835626_1836466_-\|GntR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|225543
NC_008321.1\|WP_011622329.1\|1827990_1829820_+\|excinuclease-ABC-subunit-UvrC	unknown	unknown	gnl\|CDD\|234792
NC_008321.1\|WP_041408746.1\|1823884_1825618_-\|AAA-family-ATPase	unknown	unknown	gnl\|CDD\|223994
NC_008321.1\|WP_011622335.1\|1834791_1835460_-\|DUF480-domain-containing-protein	unknown	unknown	gnl\|CDD\|183048
NC_008321.1\|WP_011622333.1\|1832962_1833871_-\|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|224054
NC_008321.1\|WP_011622326.1\|1823295_1823811_-\|bifunctional-3-hydroxydecanoyl-ACP-dehydratase/trans-2-decenoyl-ACP-isomerase	unknown	unknown	gnl\|CDD\|179953
NC_008321.1\|WP_011622320.1\|1814403_1814943_-\|hypothetical-protein	unknown	unknown	unknown
NC_008321.1\|WP_011622321.1\|1815078_1815363_-\|J-domain-containing-protein	unknown	unknown	gnl\|CDD\|365959
NC_008321.1\|WP_041408748.1\|1832418_1832661_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|368065
NC_008321.1\|WP_011071969.1\|1823011_1823188_+\|ribosome-modulation-factor	unknown	unknown	gnl\|CDD\|184747
NC_008321.1\|WP_011622325.1\|1820997_1822824_+\|DUF3466-family-protein	unknown	unknown	gnl\|CDD\|378770
NC_008321.1\|WP_011622323.1\|1818805_1819045_+\|thioredoxin-family-protein	unknown	unknown	gnl\|CDD\|368604
NC_008321.1\|WP_011622319.1\|1813645_1814404_-\|hypothetical-protein	unknown	unknown	unknown
NC_008321.1\|WP_011622324.1\|1819046_1820969_+\|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|236861
NC_008321.1\|WP_011622332.1\|1831798_1832344_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|375901

Protein	Function_ID	Function_description	E-value
NC_008321.1\|WP_011622322.1\|1816671_1818813_+\|bifunctional-23S-rRNA-(guanine(2069)-N(7))-methyltransferase-RlmK/23S-rRNA-(guanine(2445)-N(2))-methyltransferase-RlmL	gnl\|CDD\|236981	PRK11783, rlmL, bifunctional 23S rRNA (guanine(2069)-N(7))-methyltransferase RlmK/23S rRNA (guanine(2445)-N(2))-methyltransferase RlmL.	0
NC_008321.1\|WP_011622334.1\|1833867_1834698_-\|ABC-transporter-permease-subunit	gnl\|CDD\|372253	pfam12679, ABC2_membrane_2, ABC-2 family transporter protein. This family is related to the ABC-2 membrane transporter family.	2.30524e-06
NC_008321.1\|WP_011622330.1\|1829867_1830416_+\|CDP-diacylglycerol--glycerol-3-phosphate-3-phosphatidyltransferase	gnl\|CDD\|182763	PRK10832, PRK10832, CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase.	2.1908e-73
NC_008321.1\|WP_011622328.1\|1827236_1827881_+\|UvrY/SirA/GacA-family-response-regulator-transcription-factor	gnl\|CDD\|236538	PRK09483, PRK09483, response regulator; Provisional.	8.27068e-163
NC_008321.1\|WP_011622331.1\|1831415_1831691_-\|HU-family-DNA-binding-protein	gnl\|CDD\|259853	cd13831, HU, histone-like DNA-binding protein HU. This subfamily includes HU and HU-like domains. HU is a conserved nucleoid-associated protein (NAP) which binds non-specifically to duplex DNA with a particular preference for targeting nicked and bent DNA. It is highly basic and contributes to chromosomal compaction and maintenance of negative supercoiling, thus often referred to as histone-like protein. HU can induce DNA bends, condense DNA in a fiber and also interact with single stranded DNA. It contains two homologous subunits, alpha and beta, typically forming homodimers (alpha-alpha and beta-beta), except in E. coli and other enterobacteria, which form heterodimers (alpha-beta). In E. coli, HU binds uniformly to the chromosome, with a preference for damaged or distorted DNA structures and can introduce negative supercoils into closed circular DNA in the presence of topoisomerase I. Anabaena HU (AHU) shows preference for A/T-rich region in the center of its DNA binding site.	9.415e-29
NC_008321.1\|WP_011622329.1\|1827990_1829820_+\|excinuclease-ABC-subunit-UvrC	gnl\|CDD\|234792	PRK00558, uvrC, excinuclease ABC subunit UvrC.	0
NC_008321.1\|WP_041408746.1\|1823884_1825618_-\|AAA-family-ATPase	gnl\|CDD\|223994	COG1067, LonB, Predicted ATP-dependent protease [Posttranslational modification, protein turnover, chaperones].	7.75289e-115
NC_008321.1\|WP_011622335.1\|1834791_1835460_-\|DUF480-domain-containing-protein	gnl\|CDD\|183048	PRK11239, PRK11239, hypothetical protein; Provisional.	6.49542e-94
NC_008321.1\|WP_011622326.1\|1823295_1823811_-\|bifunctional-3-hydroxydecanoyl-ACP-dehydratase/trans-2-decenoyl-ACP-isomerase	gnl\|CDD\|179953	PRK05174, PRK05174, bifunctional 3-hydroxydecanoyl-ACP dehydratase/trans-2-decenoyl-ACP isomerase.	8.44582e-127
NC_008321.1\|WP_011622336.1\|1835626_1836466_-\|GntR-family-transcriptional-regulator	gnl\|CDD\|225543	COG2996, COG2996, Predicted RNA-bindining protein (contains S1 and HTH domains) [General function prediction only].	2.4035e-83
NC_008321.1\|WP_011622321.1\|1815078_1815363_-\|J-domain-containing-protein	gnl\|CDD\|365959	pfam00226, DnaJ, DnaJ domain. DnaJ domains (J-domains) are associated with hsp70 heat-shock system and it is thought that this domain mediates the interaction. DnaJ-domain is therefore part of a chaperone (protein folding) system. The T-antigens, although not in Prosite are confirmed as DnaJ containing domains from literature.	1.00355e-18
NC_008321.1\|WP_041408748.1\|1832418_1832661_-\|hypothetical-protein	gnl\|CDD\|368065	pfam04703, FaeA, FaeA-like protein. This family represents a number of fimbrial protein transcription regulators found in Gram-negative bacteria. These proteins are thought to facilitate binding of the leucine-rich regulatory protein to regulatory elements, possibly by inhibiting deoxyadenosine methylation of these elements by deoxyadenosine methylase.	0.00831016
NC_008321.1\|WP_011071969.1\|1823011_1823188_+\|ribosome-modulation-factor	gnl\|CDD\|184747	PRK14563, PRK14563, ribosome modulation factor; Provisional.	2.60865e-29
NC_008321.1\|WP_011622325.1\|1820997_1822824_+\|DUF3466-family-protein	gnl\|CDD\|378770	pfam11949, DUF3466, Protein of unknown function (DUF3466). This family of proteins are functionally uncharacterized. This protein is found in bacteria. Proteins in this family are typically between 564 to 612 amino acids in length.	0
NC_008321.1\|WP_011622323.1\|1818805_1819045_+\|thioredoxin-family-protein	gnl\|CDD\|368604	pfam05768, DUF836, Glutaredoxin-like domain (DUF836). These proteins are related to the pfam00462 family.	3.69647e-09
NC_008321.1\|WP_011622333.1\|1832962_1833871_-\|ABC-transporter-ATP-binding-protein	gnl\|CDD\|224054	COG1131, CcmA, ABC-type multidrug transport system, ATPase component [Defense mechanisms].	6.06131e-78
NC_008321.1\|WP_011622324.1\|1819046_1820969_+\|ABC-transporter-ATP-binding-protein	gnl\|CDD\|236861	PRK11147, PRK11147, ABC transporter ATPase component; Reviewed.	0
NC_008321.1\|WP_011622332.1\|1831798_1832344_-\|hypothetical-protein	gnl\|CDD\|375901	pfam18475, PIN7, PIN domain. This is a bacterial PIN-like domain of unknown function.	8.23064e-35

>NC_008321.1|WP_041408746.1|1823884_1825618_-|AAA-family-ATPase
MNSLLIPSSSLAPEFNLPTLPQSATGLKTLLLGQERVLDAFKLHNAIADQQLYLADFPGIDRQLIMQALMETVEPLPTAYLVAAQPVGKTVPFRWQYEAPLDNQDAIAEKNVSYRYLSGNIRRADLLGRMVQSANGSQYQPGALAQCHYVFICAESLWKRESLWDLVMQILTQKEYQISSHLSPIPLNCKIILIGAGLIYSQVRSEDWEFQRHFSLLAELASELDLTRFKEVQYASWLQAVAQSVEVSLEQSSLAPLFRHSARLTEHQRRLSLSMLDFAQLMAQAKVYSGKPSINAASVEHALEQANYRHNSSEEFSGQSFDDNFINLPTEGAMVGQINGLTVIDAIDHSYGEPARITATVHYGDGEVADIERKSELGGNIHAKGMMILSACLYRIFGRDAPLHLNANIVFEQSYQEIDGDSASLAEYCCLMSAIAEQPIIQSLAITGALDQFGNVQAIGGINEKIEGFFNLCERRGLTGEQGVIMPKSNVLQLNLHPKVITAVGKGQFHIYAIEHMDEAVELLMQMPAGVANEDNDFPADSLYGLVQERLDKLAGNGEEEISFMTRLLAKLGLFRH
>NC_008321.1|WP_011622326.1|1823295_1823811_-|bifunctional-3-hydroxydecanoyl-ACP-dehydratase/trans-2-decenoyl-ACP-isomerase
MNKANSFNKEELIACGHGKLFGPNSPRLPVDNMLMIDRIITINDNGGEFGKGEIVAELDINPDLWFFGCHFISDPVMPGCLGLDAMWQLVGFYLGWEGAEGKGRALGVGEVKFTGQVLPGAKKVTYKLNIKRTIHRKLVMGIADAILEVDGRQIYSATDLKVGVFSDTSTF
>NC_008321.1|WP_011071969.1|1823011_1823188_+|ribosome-modulation-factor
MKRQKRDRLDRAFSKGFQAGIGGRSKELCPYANLDSRSQWLGGWREGVDGRVNGLFNK
>NC_008321.1|WP_011622325.1|1820997_1822824_+|DUF3466-family-protein
MKSKLDKALSLVALGVLGVLHSAHAAPVYEIVNLDNYDLQGSLEGTRNGYALGVNANDELVGIAKGKKKLSTSDVEGGIIDVEDGIAPEETITYSITEAIVANNFAFIAAQNGAAGAWLPTFDSINGTTPPSDISVVNSVDTFYYGINDAGVKVGSMTAPEKKTENTATTDNATDYWYYRDYEYRGFAKVGDSEIPLPPPYTQYVKEDKTVELGGWSAATAINNNNLVVGYASTDISNYAADRVAYCLGTDNTLPLDVCIQREQYPNAQGTRNIQYQTRAYVWQLDNGVATGTALPLGLTPATDNKLTFTAQALGVNNEGVVAGRSHVYRNGSTDRLRQDAAYWSKDAEGNYQYHWIPMGESISSSIAYDVNDSGILVGSYRSYIQGYPRDKFFYFDINTPDKPYVTPNDFAATTTDLSSKPKDINNKGQVVGYIETTYDKEKPRPKAGFLYEKSTGEFSNLNNLLTCESKGFEKGADGNWTRHQVEVQDGTGKVLTYNSDILVVEATSINEDGTIVGTAFIRKPSYQFDLKGNVIVGENGLPLFELSGNGDPVTAYVPRMVVLKPTTNGEACTVDDSTDTGNYERKGAASLAWLLALPLVWLRRRVR
>NC_008321.1|WP_011622324.1|1819046_1820969_+|ABC-transporter-ATP-binding-protein
MSLVRINNGSLAYGYTPLLQNADFTIERGERVCIVGRNGAGKSSLLKILSGDVLLDEGEFNIDGSVTVSRLQQDPPKAEQGSVYSYIAAGLKEVGEALEQYHQLSHDVAFADPEQMERMLNQMQKLQETLDHHNGWQLDSRIKQNCELLGLDPDKSLSELSGGWQRKVALARALVSAPDLLLLDEPTNHLDIDTIEWLEKFLLDFQGAIVFISHDRGFIARMATRIVDLDRGVVTSWPGNYQAYLDGKQEWLRVEAEKNALFDKRLAEEEVWIRQGVKARRTRNEGRVRALKALRQERSERLNRQGNAKMAVADTDRSGKLVFDVKDLNYNLPDKNLVKNFNTTVLRGDRIALIGPNGCGKSTLIKLLIEKLQPQSGEVKVGTKLEIAYFDQYREALDPEQTVEDNVGEGKKTITINGQDRHILSYLQDFLFSPMRARTPVKALSGGEKNRLLLAKLLIRPANLIILDEPTNDLDIETLELLESLLTEYQGTLLLVSHDRAFIDNTVTSSWWYAGNGHWSEYVGGYQDAIDQGAKFYSEEPSQPNTVEAPATAKTAEVKVAEPAKAAKKLSYKLQRELEAMPELMEKLEAEILELQTTVASPDFYSQTQDKINQTLNLLADKEKQLEVCFERWEELESLK
>NC_008321.1|WP_011622323.1|1818805_1819045_+|thioredoxin-family-protein
MHNVLQAGYILYHTEGCHLCELAAALLNAAEVPFTAIDICDDEALAERYGVCIPVVKAADERCLFWPFDATQLQEFLGA
>NC_008321.1|WP_011622322.1|1816671_1818813_+|bifunctional-23S-rRNA-(guanine(2069)-N(7))-methyltransferase-RlmK/23S-rRNA-(guanine(2445)-N(2))-methyltransferase-RlmL
MLNFFAAAPKGFEYSLAQELTEFGATEIKESVAGVYFTAPLALAYRITLWTRLASRIVLVIYKGPCESAEQLYNAAYCIDWSSHFSNRNTFSIDFHGTGGFINNTQFGALKIKDAIVDRFRDDGDARPNVARIDADIKIDAHFRNGVITIAMNFSGPSLHQRGYRSTTGEAPLKENLAANMLVRSGWKAAPTTLLDPFCGSGTVLIEAALMAADIAPGLQRSRFGFEHWRRHDKATWHEILEEAKARASLGVKRCDVKFYGSDIDSRLVALAKRNAQNAGVLELIDFKVANALNVEPPAGEGYLITNPPYGERLGSVSELLQLYYQLGDKFKKEFGGWKVAMLCSDIELISALKLKADKQMKMFNGALECAFNLYTLHAQSTRRDTPVLPEGVDIADIAPAFANRIKKNAKQLEKWAKKEGIDSYRLYDADIPEYNVAVDRYLDHIVVQEYMAPASIPEAVTKRRLSDVLLALPAAIGVDPHKITMKTRERQKGTNQYQKLDERKLELITTEYGAKFKLNLTGYLDTGLFLDHRLTRRLVGQKSKGRRVLNLFSYTGSASVHAALGGAKSVTTVDMSNTYLAWAKENFALNDLSGKQYEFVQADCLQWIRDSALDKSAQYDLIFIDPPTFSNSKRMEDSFDVQRDHVNLLGMLIKLLSPNGEIVFSNNKRKFKMDTETLAKMKIKVENIDDLTLPMDYKRNPHIHNTWLITHA
>NC_008321.1|WP_011622321.1|1815078_1815363_-|J-domain-containing-protein
MINHFSVLGIKPSAKEDDIKKAYRRLSNKYHPDKLLGASDEEKEQASQQLERVKKAYEVLSDPKLRNAFIRDFNNVIVTDPNGAMRELWDQFYP
>NC_008321.1|WP_011622320.1|1814403_1814943_-|hypothetical-protein
MPMAKKLNISRINELKTNAYDNIESYDDPDTPKALEQFTSQIKKVLQADPKMLESVPEYLPVALYGRVKFPSDAKLKWAHWINTATQPEWDEFKVTIGFNNADVPLVQAVRAYSEDLLIESCAVLYLLENQGKSAPAPKRSADDHFEDEDSDYADYSDDDDDDGEEEDGYYDHYDDEDR
>NC_008321.1|WP_011622319.1|1813645_1814404_-|hypothetical-protein
MNTSLIEITVAEIKELADVEPKQASKRFELIATTMNDEQLVEVIEKMDIVTLTQINSHHDISCPSIMSELMTPEQIRDIVCQQPLYWEEKIKNNAEELIQHTFDFLTYLIRIQDSEEKQTAILECIAEDPAGLFYLSIPFIEMMLGERHDDEDHFNDYYDDEEDTDTVGYDSRAASEEAHSLSLDDPRSLMALIHELAPDVEKAIKNLLRNESSGWEMIINKFVNELVIQAKEKNQVTDEYAEVDDMFSFLD
>NC_008321.1|WP_011622328.1|1827236_1827881_+|UvrY/SirA/GacA-family-response-regulator-transcription-factor
MISIYLVDDHELVRTGIRRILEDERGIKVVGEAPDGETAVQWARQNEADVILMDMNMPGMGGLEATRKILRYQPHAKIIVLTVHTEDPFPSKVMQAGASGYLTKGATPPEVLQAIRQVSRGQRYLSPEIAQQMALSQFNPADENPFKALSERELQIMLMITNGEKVNDISEQLNLSPKTVNSYRYRLFAKLGISGDVELTRLAIRYKMLDAGHF
>NC_008321.1|WP_011622329.1|1827990_1829820_+|excinuclease-ABC-subunit-UvrC
MSTGFNAQSFLRTVSSSAGVYRMYDVKGDVIYVGKAKDLKKRLSSYFRKNLGNVKTQALVSHIHHIDVTLTHSETDALLLENDYIKQYMPKYNVLLRDDKSYPYIFLSQHEHPRLAYHRGPQREKGYYFGPYPNGGAVRESLHLMQKLFPIRQCDDLYYKSRTRPCLQYQLSRCSAPCVGKVSNAEYDEQVKLASLFLKGKDKQVISELVAKMEEAAEQQAYEQAARFRDQIMALRRVAEQQEVSGNTGDMDVIGVHYASGIACFHLLFIREGKIFGSRSYYPTVPAQTDIEEVLRSFLLQFYLNADIQRTIPKEVVISHHFEELHELEAAVSEALNKKFSIKTNVRADRASFLRLALTNATNAVMTRLSHKNTVEQRFVLLEEILELNAPIQRMECFDISHTMGESTVASCVVFNREGPHKAEYRRYNIEGITPGDDYAAMKQAISRRFDKIDASGKIPDILFIDGGLGQLRIAQQIVDEKFVNLDKAPQLIGVAKGESRKPGLETLIFGDTESSFSLEDDSPALHLIQHIRDESHRFAITGHRNRRQKTRNTSTLESIPGIGPKRRKALLQHLGGLQEVKGASVAELAKVPGISIEMAQTIHDALRG
>NC_008321.1|WP_011622330.1|1829867_1830416_+|CDP-diacylglycerol--glycerol-3-phosphate-3-phosphatidyltransferase
MPFNLPIALTLFRLFLLPIFVVLFYLPYSWTPFVAAFVFWLAAITDALDGYAARKLKQLTRFGAFLDPVADKLMVITALVLLVDQYADIWLTLPALFMIGREIVISALREWMAELGKRGTVAVSWIGKYKTAAQMVAIIGLIWQYNPLMIQAAFVLLYIAAVLTFWSMMSYILAAWKDLTAE
>NC_008321.1|WP_011622331.1|1831415_1831691_-|HU-family-DNA-binding-protein
MNKAQLIQRIATSLEQSQASTKPVVEQILQQIHIALSEGEKVFLPQFGTFELRYHLPKSGRNPQTGETIEIAGFNQPSFKAATALKQAINE
>NC_008321.1|WP_011622332.1|1831798_1832344_-|hypothetical-protein
MKWAFIDYENVGNLEKIDLSIYQKIIIFLGAKQPKIDFGEKKYDKPLEIIVIQLKATQSNNLDFHLSYYLGCYESTASENVTFDIISNDNGFAPLIAHIKANGRICKHIKLATVENISAKLLHSLTSKPKEKRPKKVDSLRNHIASHMGIKGNQIAIQGYLNQLINDKVISVSEDKVSYHR
>NC_008321.1|WP_041408748.1|1832418_1832661_-|hypothetical-protein
MATRESMKQWIVEYLNSSGGRGSPRDVSKYVWEKYESELKSSGDLLYTWQYDIRWAAQKLRNEGVLKSVNGRRDLPWELN
>NC_008321.1|WP_011622333.1|1832962_1833871_-|ABC-transporter-ATP-binding-protein
MILIQCQGLSKHYGSKKALNNVNLTLESGAPIALVGPNGAGKTTLFSLLCGYLTPSAGTVRILGEAPNSPALLGQIAALPQDATLDPNLTIISQLSFFARLQGMDSKQAHQEALRVLNLVDLAEVAQQKPPSLSHGMSKRVAIAQALIGSPKLVLLDEPTAGLDPANAKKIRELVRTLSPTTTFVISSHNLEELEKLCDQVLYLDKGELGQSISMRSSNSGSDYLTLTMESCDSEALIQAVGQIAGVVNITSKQAHVFVIQLDDTVNPPYEFETALLALFKQQHWQYKMLLKGRTLEETLFS
>NC_008321.1|WP_011622334.1|1833867_1834698_-|ABC-transporter-permease-subunit
MTPNAPSTFNNMLLIAGFECRKFLFNLRGIIALIAFALVWGILLLYPIQGASTLLMQPNVKDLIDGLLGSQALNVLFDWPVAEMAIFWCFALYLFPMFSILIAADQFSSDKTRGTLRFYTLRTSKDSLLFGRFLGQILIQGLLILLTILATIALALTRDIGLLLPALTSGALVGVNLVIVILPFTAVMTLLSLYANTARQAMVLATILWTVVSIALLILGNQSSLFEGLQWILPGAQLSNMVNTNGLNSFAYAPIPLLQTAFALFLGRVYIQRSQL
>NC_008321.1|WP_011622335.1|1834791_1835460_-|DUF480-domain-containing-protein
MELTLHEARVIGCLLEKEVTTPEQYPLSLNALTLACNQKTSRDPVLDLSEALVQDALDSLNKKRLISEQSGFGSRVVKYKHRFCNTEFSELQLSSAAVAIICLLLLRGPQTPGELRTRSNRLHDFKDVLEVEACIKQLMERDKPVLAQLPREPGKRECRYAELFSQGAEQINAASLSADSPSAGSNSLNAQDRQQLEARVTQLEEQVAELKDKLDSLIASLS
>NC_008321.1|WP_011622336.1|1835626_1836466_-|GntR-family-transcriptional-regulator
MIQIGKTCKLEVVKQVSFGVYLNAHEFGQVLLPNKATPKDCQVGDWLEVFLYLDSEDIVIATTRKPLAQVGEFAYLKAVATGPYGAFLDWGLDKDLLLPFGEQHKPIEEGRSYLVYVHVNRADERIVASSKIDKFLDKTPAQYEVGQQVDLYIGGTTDLGYKAIINHAHWGVIYQNEVFQKLRFGQRVKGFIKQVRRDGKIDLVLQQGSKQELDKHAHIILVKLKQAGGFLPLTDKTDAEVIYEQLGMSKKAFKKSIGGLFKAGKLSIDDDGLRLTEAD

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Crispr_ID: NC_008321_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_008321_2

4123507-4123613

Orphan

Consensus_repeat	Method
TGAAGCCCCACGATTTTGATTCACCTCGGCCGT	CRISPRCasFinder

1 spacers

The CRISPR arrays of NC_008321_2

>merge|NC_008321|2|4123507-4123613|CRISPRCasFinder
TGAAGCCCCACGATTTTGATTCACCTCGGCCGTGAGGCCGCTATGACGATACATCTACATAAACAAGTGTGAAATGAAGCCCCACGACTTTGATTCACCTCGGCCGT

>NC_008321|2|2|4123507-4123613|CRISPRCasFinder
TGAAGCCCCACGATTTTGATTCACCTCGGCCGT	GAGGCCGCTATGACGATACATCTACATAAACAAGTGTGAAA
TGAAGCCCCACGACTTTGATTCACCTCGGCCGT

Protein	Signature genes	Signature genes Name	Protein_function
NC_008321.1\|WP_011624181.1\|4124833_4125544_-\|oxidative-stress-defense-protein	unknown	unknown	gnl\|CDD\|236840
NC_008321.1\|WP_011624184.1\|4128193_4129039_+\|transporter-substrate-binding-domain-containing-protein	unknown	unknown	gnl\|CDD\|270422
NC_008321.1\|WP_011624172.1\|4113674_4114418_+\|sulfite-exporter-TauE/SafE-family-protein	unknown	unknown	gnl\|CDD\|376667
NC_008321.1\|WP_011624180.1\|4123777_4124563_-\|class-I-SAM-dependent-methyltransferase	unknown	unknown	gnl\|CDD\|379312
NC_008321.1\|WP_011624182.1\|4125964_4127395_+\|30S-ribosomal-protein-S12-methylthiotransferase-RimO	unknown	unknown	gnl\|CDD\|237838
NC_008321.1\|WP_011624179.1\|4121841_4122747_+\|endonuclease/exonuclease/phosphatase	unknown	unknown	gnl\|CDD\|377028
NC_008321.1\|WP_041408896.1\|4122758_4123235_+\|hypothetical-protein	unknown	unknown	unknown
NC_008321.1\|WP_011624173.1\|4114531_4115476_-\|polysulfide-reductase	unknown	unknown	gnl\|CDD\|274450
NC_008321.1\|WP_011624188.1\|4133560_4136050_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|376772
NC_008321.1\|WP_011624187.1\|4132997_4133531_+\|ribosome-associated-protein	unknown	unknown	gnl\|CDD\|235377
NC_008321.1\|WP_011624177.1\|4119858_4120170_+\|hypothetical-protein	unknown	unknown	unknown
NC_008321.1\|WP_011624174.1\|4115478_4116045_-\|4Fe-4S-dicluster-domain-containing-protein	unknown	unknown	gnl\|CDD\|274451
NC_008321.1\|WP_011624189.1\|4136102_4137434_-\|APC-family-permease	unknown	unknown	gnl\|CDD\|223605
NC_008321.1\|WP_041408894.1\|4116057_4118340_-\|thiosulfate-reductase-PhsA	unknown	unknown	gnl\|CDD\|237973
NC_008321.1\|WP_011624183.1\|4127710_4127938_-\|alternative-ribosome-rescue-factor-A	unknown	unknown	gnl\|CDD\|367714
NC_008321.1\|WP_011624176.1\|4118828_4119455_-\|pentapeptide-repeat-containing-protein	unknown	unknown	gnl\|CDD\|224276
NC_008321.1\|WP_083757936.1\|4129235_4131362_+\|TonB-dependent-receptor	unknown	unknown	gnl\|CDD\|273807
NC_008321.1\|WP_011624178.1\|4120156_4121260_+\|phosphoribosylaminoimidazolesuccinocarboxamide-synthase	unknown	unknown	gnl\|CDD\|184420
NC_008321.1\|WP_011624186.1\|4131478_4132822_-\|metalloprotease-PmbA	unknown	unknown	gnl\|CDD\|182922
NC_008321.1\|WP_011624171.1\|4113258_4113573_+\|met-regulon-transcriptional-regulator-MetJ	unknown	unknown	gnl\|CDD\|179982

Protein	Function_ID	Function_description	E-value
NC_008321.1\|WP_011624181.1\|4124833_4125544_-\|oxidative-stress-defense-protein	gnl\|CDD\|236840	PRK11087, PRK11087, oxidative stress defense protein; Provisional.	5.1304e-120
NC_008321.1\|WP_011624184.1\|4128193_4129039_+\|transporter-substrate-binding-domain-containing-protein	gnl\|CDD\|270422	cd13704, PBP2_HisK, The periplasmic sensor domain of histidine kinase receptors; the type 2 periplasmic binding fold protein. This subfamily includes the periplasmic sensor domain of the histidine kinase receptors (HisK) which are elements of the two-component signal transduction systems commonly found in bacteria and lower eukaryotes. Typically, the two-component system consists of a membrane-spanning histidine kinase sensor and a cytoplasmic response regulator. The two-component systems serve as a stimulus-response coupling mechanism to enable microorganisms to sense and respond to changes in environmental conditions. Extracellular stimuli such as small molecule ligands and ions are detected by the N-terminal periplasmic sensing domain of the sensor kinase receptor, which regulate the catalytic activity of the cytoplasmic kinase domain and promote ATP-dependent autophosphorylation of a conserved histidine residue. The phosphate is then transferred to a conserved aspartate in the response regulator through a phospho-transfer mechanism, and the activity of the response regulator is in turn regulated. The sensor domain belongs to the type 2 periplasmic-binding fold protein (PBP2) superfamily, whose members are involved in chemotaxis and uptake of nutrients and other small molecules from the extracellular space through their function as an initial high-affinity binding component. PBP2 typically comprises of two globular subdomains connected by a flexible hinge and bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap.	3.41084e-13
NC_008321.1\|WP_011624172.1\|4113674_4114418_+\|sulfite-exporter-TauE/SafE-family-protein	gnl\|CDD\|376667	pfam01925, TauE, Sulfite exporter TauE/SafE. This is a family of integral membrane proteins where the alignment appears to contain two duplicated modules of three transmembrane helices. The proteins are involved in the transport of anions across the cytoplasmic membrane during taurine metabolism as an exporter of sulfoacetate. This family used to be known as DUF81.	2.30712e-08
NC_008321.1\|WP_011624179.1\|4121841_4122747_+\|endonuclease/exonuclease/phosphatase	gnl\|CDD\|377028	pfam03372, Exo_endo_phos, Endonuclease/Exonuclease/phosphatase family. This large family of proteins includes magnesium dependent endonucleases and a large number of phosphatases involved in intracellular signalling. This family includes: AP endonuclease proteins EC:4.2.99.18, DNase I proteins EC:3.1.21.1, Synaptojanin an inositol-1,4,5-trisphosphate phosphatase EC:3.1.3.56, Sphingomyelinase EC:3.1.4.12, and Nocturnin.	2.00078e-06
NC_008321.1\|WP_011624182.1\|4125964_4127395_+\|30S-ribosomal-protein-S12-methylthiotransferase-RimO	gnl\|CDD\|237838	PRK14862, rimO, 30S ribosomal protein S12 methylthiotransferase RimO.	0
NC_008321.1\|WP_011624180.1\|4123777_4124563_-\|class-I-SAM-dependent-methyltransferase	gnl\|CDD\|379312	pfam13649, Methyltransf_25, Methyltransferase domain. This family appears to be a methyltransferase domain.	8.09924e-15
NC_008321.1\|WP_011624173.1\|4114531_4115476_-\|polysulfide-reductase	gnl\|CDD\|274450	TIGR03148, cyt_nit_nrfD, cytochrome c nitrite reductase, NrfD subunit. Members of this protein family are NrfD, a highly hydrophobic protein encoded in the nrf operon, which encodes cytochrome c nitrite reductase. This multiple heme-containing enzyme can reduce nitrite to ammonia. Members belong to a broader Pfam protein family, pfam03916, which also contains an NrfD-related subunit of polysulphide reductase. [Energy metabolism, Electron transport].	1.76093e-84
NC_008321.1\|WP_011624188.1\|4133560_4136050_+\|hypothetical-protein	gnl\|CDD\|376772	pfam02369, Big_1, Bacterial Ig-like domain (group 1). This family consists of bacterial domains with an Ig-like fold. Members of this family are found in bacterial surface proteins such as intimins and invasins involved in pathogenicity.	1.58079e-06
NC_008321.1\|WP_011624187.1\|4132997_4133531_+\|ribosome-associated-protein	gnl\|CDD\|235377	PRK05255, PRK05255, ribosome-associated protein.	7.35711e-75
NC_008321.1\|WP_011624174.1\|4115478_4116045_-\|4Fe-4S-dicluster-domain-containing-protein	gnl\|CDD\|274451	TIGR03149, cyt_nit_nrfC, cytochrome c nitrite reductase, Fe-S protein. Members of this protein family are the Fe-S protein, NrfC, of a cytochrome c nitrite reductase system for which the pentaheme cytochrome c protein, NrfB (family TIGR03146) is an unambiguous marker. Members of this protein family show similarity to other ferredoxin-like proteins, including a subunit of a polysulfide reductase. [Energy metabolism, Electron transport].	4.52195e-89
NC_008321.1\|WP_011624189.1\|4136102_4137434_-\|APC-family-permease	gnl\|CDD\|223605	COG0531, PotE, Amino acid transporters [Amino acid transport and metabolism].	1.16384e-45
NC_008321.1\|WP_041408894.1\|4116057_4118340_-\|thiosulfate-reductase-PhsA	gnl\|CDD\|237973	PRK15488, PRK15488, thiosulfate reductase PhsA; Provisional.	0
NC_008321.1\|WP_011624183.1\|4127710_4127938_-\|alternative-ribosome-rescue-factor-A	gnl\|CDD\|367714	pfam03889, DUF331, Domain of unknown function. Members of this family are uncharacterized proteins from a number of bacterial species. The proteins range in size from 50-70 residues.	2.38466e-20
NC_008321.1\|WP_011624176.1\|4118828_4119455_-\|pentapeptide-repeat-containing-protein	gnl\|CDD\|224276	COG1357, COG1357, Pentapeptide repeats containing protein [Function unknown].	7.19298e-13
NC_008321.1\|WP_083757936.1\|4129235_4131362_+\|TonB-dependent-receptor	gnl\|CDD\|273807	TIGR01785, Heme/hemopexin_utilization_protein_C, TonB-dependent heme/hemoglobin receptor family protein. This model represents the TonB-dependent outer membrane heme/hemoglobin receptor/transporter found in bacteria which live in contact with animals (which contain hemoglobin or other heme-bearing globins) or legumes (which contain leghemoglobin). Some species having hits to this model such as Nostoc, Caulobacter and Chlorobium do not have an obvious source of hemoglobin-like proteins in their biological niche and so the possibility exists that they act on some other substance. [Transport and binding proteins, Cations and iron carrying compounds, Transport and binding proteins, Porins].	6.16308e-44
NC_008321.1\|WP_011624178.1\|4120156_4121260_+\|phosphoribosylaminoimidazolesuccinocarboxamide-synthase	gnl\|CDD\|184420	PRK13960, PRK13960, phosphoribosylaminoimidazole-succinocarboxamide synthase; Provisional.	0
NC_008321.1\|WP_011624186.1\|4131478_4132822_-\|metalloprotease-PmbA	gnl\|CDD\|182922	PRK11040, PRK11040, peptidase PmbA; Provisional.	0
NC_008321.1\|WP_011624171.1\|4113258_4113573_+\|met-regulon-transcriptional-regulator-MetJ	gnl\|CDD\|179982	PRK05264, PRK05264, met regulon transcriptional regulator MetJ.	1.01741e-76

>NC_008321.1|WP_041408896.1|4122758_4123235_+|hypothetical-protein
MPINFEDLLNLGKESADLVIRNNSEIDETIESFRVSLSTFLNLNINFTEEIEYEDDTNSIAARIRITNNLFEPRKKTGYSYICVQHTETGVTRRLIKIQRSNDGYPITVIIDKSHYINDNQEEFARALGAIASNSQTHLTLRSFQRMVEEKNTQTKTN
>NC_008321.1|WP_011624179.1|4121841_4122747_+|endonuclease/exonuclease/phosphatase
MLLYNLRFGWWNVALSPSAPQAKSKANATTYPIICTHIETLLQDNSCDFLALCEVSSEDIRYFSENIKLEHISILNLTDKIGKTRFDLAVIYKTSKIKVNHINSLSKILTDNTVKASQLVEVENIDDSRKIYIYLCHWPSRLNGNSEEKRIAAANIVYNSASTLIESGKDVIIMGDFNDNPYDISLYKCLKASRCHDAVKKYPSEYFYNPFWRSIVSENKYSHSGITNTYRSGSYKYKQFMGEIWHSYDQIIVSGSFINNTYWHLNEFRTQVITPEVILKNYEDNSHFIDHLPIVCEITRV
>NC_008321.1|WP_011624178.1|4120156_4121260_+|phosphoribosylaminoimidazolesuccinocarboxamide-synthase
MSLADSVLAVNNDLPIRTDNPVHSGKVRSVYWLTDADSRRLIQTKGYNVPEDTPLAIMVISDRISAFDCIFHGEGGLKGIPGKGAALNAISNHWFKLFAENGLADSHILDIPHPFVWIVQKARPIKVEAICRQYITGSMWRAYSKGERVFCGITLPEGLEKDQKLPDLLITPSTKGILTGIPGVPAQDDVNISRSDIEANYQAFGFEKVEDIDLYEKLLKDGFKVIAKALADLDQVFVDTKFEFGYVTDKNGNSKLIYMDEVGTPDSSRIWDGAAYRDGKILENSKEGFRQFLLNHFPDPDILLNKDRMPEREALARDNALPLEAMMDVSRTYTGIAEKVTGAAIPLPANPKADIIKILREEYDLIV
>NC_008321.1|WP_011624177.1|4119858_4120170_+|hypothetical-protein
MVSLFEQNGTGFPRLNRPDSLWRQPCSACYFSLLSRPSLSCLSPENILLALRFNLTNLLCALSDKLLVNNKKVAKHLRLKHTATNKKLVPTLSIQRNTRHESC
>NC_008321.1|WP_011624176.1|4118828_4119455_-|pentapeptide-repeat-containing-protein
MTDVKTPMMARAASEGRYFFSQQFIALAESQTQWQELEFEECEFHDCQFSDSTFRNCKFIDCRFVGCNLSLLKVPLSQFNGVSFEECKLVGIDWTRAAWPRLSFAAPFSFRTCILNDCSFMGLQLDEMVLEGCKAQDVDFREGKFNRANFSYSDFRHSLFGRTELMEADFSEATDYDIDIFNNKIKGAKFSRDEAIRLLNGLEITLVD
>NC_008321.1|WP_041408894.1|4116057_4118340_-|thiosulfate-reductase-PhsA
MIELNRRTFLKGAGASGATCALASLLPGSLAALESKQLKGMGKDIASICEMCSTRCPISARVIEGKNVFISGNKAAKSFGGKVCARGGAGHSLLYDPQRIVKPLKRVGERGEGKWAEISWDEAYQLIADNLNKIKQAYGPEAVAFSSKSGSQEKHLFHLATAFGSPNTFTHASTCPGGYEIAAKAMFGTKVKRDLSNSKYIINFGHNLYEGINMSETRGMMAAQMDKGAKLVVFEPRFSIVADKADEWYAIRPGTDVAVALALCHVLIEDNLYDKAFIERYVEGFDAFAAEVKAYTPEWAETVSDVPAKDIRRIAHEYAAKAPHAVVDFGHRATFTTEEFEMRRALYAANILIGNIERKGGIYLGQKPSDYNKLAGESVAPVLGKPGVKDMPKPAAKRIDQVEEQYAMMWSSGGIYQTILDATLTAVPYQLHGWVMSRTNPMQTMTDRARVVEALKKLDFVAVCDVYISETAAYADVILPESTYLERDEEIADKSGKNPAYYVRQRVVETLGDTKPSWQIFKDIGHKLGLSEFYPWDNMETLQLLQVNRDTALLRRIKDEGFVSFGKPIMLREPKMVAEFTKAYANAKAVDEDGTYGSLLSFKTPSGKIELTSAKVEAMAPGRGVIKFREVHLKKADELYFIQGKVAVHTNGATHNIPMLANLMSDNAIWVHPVTAGKLGISNGDPIRLTSSVGSEEGHALVTPGIRPDTVFAYMGFGSKNKELVRATGKGIHCGNLLPHQTAPVCGMNIHTTGVTLAKR
>NC_008321.1|WP_011624174.1|4115478_4116045_-|4Fe-4S-dicluster-domain-containing-protein
MTKRYVMVHDENKCIGCQACNVACRSENGVPEGVTRLQVRVEGPFGEMPHLHFKYHRVSCQQCEDAPCVKVCPTGAAYVGEDGIVSIHGDKCVGCMYCVAACPYKVRFMNPETKVADKCNFCKDTRLARGEEPACVTVCPTDALVFGDANDPQSEVAMLLNTKITYQDKTHLGTQPRVYRVPTKRGGI
>NC_008321.1|WP_011624173.1|4114531_4115476_-|polysulfide-reductase
MNNTWGDMAQYDPVTWHWIIAVYLFMAGLSAGSLLIGIGLRWFNKEQAQGETSILKAAAIIGPVAICLGLACLVFDLTKPFHFWLILINYNFQSVMAIGVLALLAYSPLAFAYAILVLRDELPKWGLGFLVPIAKLLMPFRKPIEVLLFILAIGVGAYTGFLISAMNAYPMLNTAVLPALFLVSGLSAGAAANAVLALVMFKTDSHDKTLAKMHGLELPVMAIEIMFLFMLFCALYFKGGAAAAALASLTSGVWASVFWIGVVGIGFGIPLLFMLLPTATRHSKGAMIMVACASLTGVLALRHFIVYAGQSYLS
>NC_008321.1|WP_011624172.1|4113674_4114418_+|sulfite-exporter-TauE/SafE-family-protein
MFSLIDPQTLAIASVIVFLGALTQSLIGFGLAVVASPLLYIVDPELVPAPVIVMGFSIALLTLLRERGHLEFNGLQYALIGRVPGGFIGASLLLFAPQPILGLAIAGIVAVAVVLSLYKLTLPVNKATLFGAGVVSGIFGNIAAIGGPPMAILLAGKDASKFRAALSAFFIFSSTIALVILGVTGLLEIKHLWLSLMLLPSVFLGYLVAGKLVGNVDKHKTKMATLALCAISALVLTVKSVIELLPQ
>NC_008321.1|WP_011624171.1|4113258_4113573_+|met-regulon-transcriptional-regulator-MetJ
MTEWNGEYISPYAEHGKKNEQVKKITVSIPLKVLKVLTDERTRRQVNNLRHATNSELLCEAFLHAYTGQPLPNDADLSKDCPDSIPAEAKRLMDEMGIEWEDME
>NC_008321.1|WP_011624180.1|4123777_4124563_-|class-I-SAM-dependent-methyltransferase
MSSNALYTDLSGYYDLMCSDINYQQQSASIHRLHQFLGNNGKQHLDLACGTGPHVRHFIDLGYQCRGLDINQPMLDMAMRRCPEAQFNLQDMTAFYLEQPVDLITCFLYSIHYSAGIERLKSCIASVHRALNDGGIFCFNSVDKHRIDNRLSIKHFAEFEGHHFAFESGWHYSGQGENQSLNLSIAKSLQPFTQQADFEGDTSAHQTELWQDQHTMVATSFAELQALLAPYFEVHIFEHDYEKIVPWDLSSGNALFVCVKI
>NC_008321.1|WP_011624181.1|4124833_4125544_-|oxidative-stress-defense-protein
MKHSLLAVLVAGGLFSGVFTAKAMAADVDFPHIETMGVSQIQVEPDMAELNVEVAVTEKEAKAAKDNSDAAVAKFIARLTAAGITKEQIQSANLNLQPQYVYAQDKAPELSGYTASRQITVTISDLARLNTILDSALEEGINRVNNIALKSSKEAEYVAKARQAAIVDAKQKAESLAKGFGENLGKVWQIRYYDQRPVQPVMLRMNAKADAMGAAESYQYGQVTIEDRVEVVYKLK
>NC_008321.1|WP_011624182.1|4125964_4127395_+|30S-ribosomal-protein-S12-methylthiotransferase-RimO
MTVETFNPKQTTTLETPAKTLEAASADSTATGNRIGFVSLGCPKNLVDSERILTQLRIDGYEVTNSYDNADLVIVNTCGFIDAAVEESLDAVREALEENGKVIVTGCLGAKENQIREVHPDVLEITGPHSYEAVLKHVHKYVPKPEHNPFTSLIPQTGVKLTPKHYAYLKISEGCDNRCTFCIIPALRGDLDSRPAGSVLDEAKRLVESGVQEILVVSQDTSAYGKDKGGRTDFWNGMPVKQDITSLARQLGKMGAWVRLHYIYPYPWVDDLIPLMAEGLILPYLDIPMQHASPRILKMMKRPGRVDRQLEAIQRWREICPDLVIRSTFIVGFPGETEEDFEMLLDFLREARLDRVGCFKYSEVEGAVANTIAELISEDVKEDRYHRFMEVQAEISAERLARFVGRTMDILIDDVDEEGAIGRSFADAPEIDGMVFINGETELEPGMLVRAVITHSDEHDLWAELVDADAEDDIEA
>NC_008321.1|WP_011624183.1|4127710_4127938_-|alternative-ribosome-rescue-factor-A
MAKLKETSVLEHENGRGTITDNALKAVVTSSLFRMRTEKPKKGKGSYNRKAANRKGYQHRGDTPFDFMGVCLTGA
>NC_008321.1|WP_011624184.1|4128193_4129039_+|transporter-substrate-binding-domain-containing-protein
MQFAVIYRPLLSLVFLLVSLFPSLAQAFSSSECIITMGYRTSERLPFIQHEPNNQGFYRDIYQAAAERIGCKLRITRAPKMRILRDLKLGNIDFYPGLSFSEERAQFAFFIPNGLSERAIGISRAGAANIRSLEQLSQSGMTLLIAPGSYDFNGLPETMSVRKPPELDVPKALDYLLASQGDFFIYDQATISYYLKQRDMSQFKLHPNCCQQPQAMYLGFSKKSRHFRGQHNPNYRADLPVSADNSPNRLAEDSKAYEFAKALAAMDAEGETQRIYFNHFG
>NC_008321.1|WP_083757936.1|4129235_4131362_+|TonB-dependent-receptor
MAANASTIPHGFKCSAIASALTLALGASVASQAMADETNQTQIERIQVHGEQSIGRNALGSADALLKDQGVDFSEAGGVSALPVLNGMMGDRIKVLVDGADITASCANQMNPPLSYVSANQISSVEVVAGVSPVSAGGDNIAGVIKVNSLNPKFSDSEDLSFESGEISSGYRSTSDAFLLGAKAGIASKNLSFSYQGAYEDANSYHDGHGDKVLDTLYRAQNHALTAAWRDDTQQLAIKLTHQAIPFQGFPNQYMDMTDNKSYGALVRYLRDLDNDGEFSAQLNWHSVKHEMGFFTPEKTGKMPMNTEGSDYSYQLHWRLPIGDDSTLLVGQEFYNYQLDDTWPAVPGTMMAPNDYININDGERRRAAVYGEWQQNLTPLWWLSAGVRYEYATTDTGEVQAYSNMPMMGMPNMDAEAAKAFNAMDRSRDDNLIDATLLARYQLSAKQQLEFGLARKNRAPNLYERYSWGRGVMATTMIGWYGDGNGYVGNPDLKPETAHTLSAAYKFAGDEWQFSTTAWYSAVTDYIDAEVIGSFNRTGLASGKRNILKFTNEDAHLYGAKLSANYLLADTDSGKWQMQGKLNITRGERDEGNEPLYQIKPLQTELALSHQLGDWENRLSWQWVATKDKVDDRRLENETDSYSLLNLSSSIKWQELSLTFAINNLFDTYYELPLGGVNLAEFKADSSGGFSQFAGSGRSFELGASYRF
>NC_008321.1|WP_011624186.1|4131478_4132822_-|metalloprotease-PmbA
MSLNRIDSELAALKDAVAVALEYANKLGTNAAEVAISKQQGLSVSTRLKEVETVEFNKDGALGITVYRDGCKGSSSTSDLSPEAIALAVKAADDIARYTSADPFSGLADKALMATEIRDLKLYYPEDISPDELAQLAIRAETAALDADPRINNSDGASANAHTSVKVYGNSHGFLNGYCSSRYSLSCSVIGEDSDGSMQRDYDYTIARKFSEMLSPESVGLKTAQKTVSRLGARKIATSRLPILLSPEIATGLIGHLVGAISGGSLYRKSSFLLDAIHTQIFPDWFNIEEQPHLLGALASANYDSEGVATQDRRIIDRGMLESYLLTSYSARKLGLTNTGHAGGIYNWTLAHTGQSFDELVKGMGTGLIVTEVMGQGVNMVTGDYSRGAAGFYVENGEVQFPVEEITIAGNLKDMFRGIQAVSKDFDLRSSIRTGGILLSEMKVAGN
>NC_008321.1|WP_011624187.1|4132997_4133531_+|ribosome-associated-protein
MKIVGDSEHFKQPYDSDEEYVSKTEDKRDCEAAQKVGMELVSLSKTQLDKIELDEHLYDSIQQAHKIKPKTEAYRRHMQYIGKLMRHVDVEPIKAALAVVLNKNSNETAKLQIFEKMRERLLSQGDSEIQTLVEHYPQLDRQKLRTLVRQATKELAKGPESKSSKELFKYLRSEIQD
>NC_008321.1|WP_011624188.1|4133560_4136050_+|hypothetical-protein
MRFSNTFCNLTLLSIGLFGLWGCNGPSDEDNGGTDASDGIYKLSIDFKTLSGSQCGSFTSLQSFPKDAGFCAVAKLNKGSAKVSNQRVNFTSDLGALTPESKLTDSNGEAIVIVSNPDLLINAGTITATTTPSDSSTALSATRNFEFTGTIDGIGASIAPKLSASIQSSANVVTRFKVDEAVQLQAIFLDAESNGIADAKVTFSAGSATLTPTSALTNSQGIAQVSYTPSATELGANALTVTVEYQGQSLQSSSLYEVLSKDAVNEAGTLKLGSFNGSSFTEGKLASTLTAQADGSYKISAGGSFGVTASLVLEASDGTVTRVQTPSSISFSSDCTASNNASLDSPVTTLSGNASSTFQDTSCSGNSERNDQIVATTVVGNQTLTANFPFTLQRQTLASLSFEAAEPNQIRIKGAGGTGSSESSLVSFKVTSANGQPAAQQKVSFSLDTVVGGLSFANGSANAEGQTNAQGIASVRVLSGTVPTPVRVVASAVDADTKEVITSQSEQLTVNTGLPQQLGFSLSTTISNPEAGDYDGETATITARLSDSFGNPAPDDTTVNFNTEGGQIAPSCLTQNGACSVTWTSGAYRPQDHRITILAYALGHETFFDTNGNNQFDSADGGAITNACLFNGVATHCSGNGMDVETFHNSGFSDLPTAFRDDNENFSRDSGEPYFDNLARETYPVADGKFNGPQCEGSLCGTGQANKIYIRKALVLSMSGSQAYISVQQDGVFLASVNDIKPVAAGAESEFVVFVHDSAKQIMPAKTQIELCVDCNGTPDIIEVANTLTGKNGLGTPLSFTASAGSQISIVTTTPKQVKTSLNFTVPTL
>NC_008321.1|WP_011624189.1|4136102_4137434_-|APC-family-permease
MSQQNPGLKQSLSLWQVVVMGLAYLTPMAVFDTFGIVSEITSGHVATSYLLALAGILFTAFSYGHLVRKYPYAGSAYTYAQKTFSPNVGFMVGWSSLLDYMFMPMINMLLAKIYLTAMFPNVEPWIFIFGLVAVMTVLNLRGIDLVANFNGVIVFAQIAIILVFIGLMAHSLSLGEGEGVIASVRPFYSEEISLAPLFTGATILCFSFLGFDGLSSLSEETKDAKRVIPRAIVLTALIGGVIFVSVSYFLQLFFPDISRFQQLDAVLPEIALYVGGNLFQSVVLVATTIAVLASGMAAHAGVARILYVMGRDNMLPNKGFGYIHPKWRTPAFNVILVGLLALSAVSFDLEMALALVNFGALVAFTFVNLSVIVQFYIKEKRNQSLKDHFQYFVLPLCGAATIGVLWLNLEPQSLELGLIWAAVGVLYLALRSLRLRKTVELQN

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

1283817 : 1291273

Staphylococcus_phage(50.0%)

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_011621884.1\|1283817_1285485_-	energy-dependent translational throttle protein EttA	A0A1V0SKJ1	Klosneuvirus	1.1e-38	27.6
WP_011621885.1\|1285674_1286928_+	serine hydroxymethyltransferase	A0A219Y950	Aeromonas_phage	1.6e-101	53.4
WP_011073317.1\|1287138_1287588_+	transcriptional regulator NrdR	NA	NA	NA	NA
WP_011621886.1\|1287675_1288821_+	bifunctional diaminohydroxyphosphoribosylaminopyrimidine deaminase/5-amino-6-(5-phosphoribosylamino)uracil reductase RibD	A0A1V0SE20	Indivirus	7.5e-50	34.6
WP_011621887.1\|1288828_1289485_+	riboflavin synthase	A0A2H4PQS5	Staphylococcus_phage	8.7e-27	34.0
WP_011621888.1\|1289552_1290656_+	bifunctional 3,4-dihydroxy-2-butanone-4-phosphate synthase/GTP cyclohydrolase II	A0A2H4PQS2	Staphylococcus_phage	5.8e-68	39.7
WP_011073313.1\|1290796_1291273_+	6,7-dimethyl-8-ribityllumazine synthase	A0A2H4PQS3	Staphylococcus_phage	1.0e-29	45.7

DBSCAN-SWA_2

1310517 : 1325661

uncultured_Mediterranean_phage(25.0%)

tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_011621904.1\|1310517_1311813_+	phosphopyruvate hydratase	A0A1X9I5Z8	Streptococcus_phage	4.0e-132	58.7
WP_011621905.1\|1311913_1312213_+	cell division protein FtsB	NA	NA	NA	NA
WP_011621906.1\|1312223_1312973_+	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase	NA	NA	NA	NA
WP_011621907.1\|1313024_1313504_+	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase	NA	NA	NA	NA
WP_011621908.1\|1313533_1314661_+\|tRNA	tRNA pseudouridine(13) synthase TruD	NA	NA	NA	NA
WP_011621909.1\|1314657_1315407_+	5'/3'-nucleotidase SurE	A0A1B1ITZ2	uncultured_Mediterranean_phage	1.3e-71	52.2
WP_011621910.1\|1315403_1316039_+	protein-L-isoaspartate(D-aspartate) O-methyltransferase	A0A1B1IU40	uncultured_Mediterranean_phage	9.9e-36	51.2
WP_011621911.1\|1316136_1317033_+	peptidoglycan DD-metalloendopeptidase family protein	I3PV79	Clostridium_phage	2.6e-10	31.0
WP_011621912.1\|1317113_1318094_+	RNA polymerase sigma factor RpoS	F4YCU2	Synechococcus_phage	1.4e-33	32.9
WP_011621913.1\|1318234_1320820_-	DNA mismatch repair protein MutS	A0A1V0SC35	Catovirus	6.7e-30	23.1
WP_011621914.1\|1321202_1322276_+	recombinase RecA	A0A2D1GPX2	Mycobacterium_phage	1.4e-111	61.9
WP_041408728.1\|1322350_1322761_+	regulatory protein RecX	NA	NA	NA	NA
WP_011621916.1\|1323036_1325661_+\|tRNA	alanine--tRNA ligase	A0A1V0SK38	Klosneuvirus	4.2e-80	39.2

DBSCAN-SWA_3

2066659 : 2076886

Faustovirus(12.5%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_011622512.1\|2066659_2067874_+	IscS subfamily cysteine desulfurase	A0A0H3TPH2	Faustovirus	6.7e-33	31.1
WP_011072277.1\|2067911_2068295_+	Fe-S cluster assembly scaffold IscU	A0A218MKD1	uncultured_virus	1.0e-51	77.4
WP_011072278.1\|2068309_2068633_+	iron-sulfur cluster assembly protein IscA	A0A2H4N7N5	Lake_Baikal_phage	4.1e-22	43.0
WP_011622513.1\|2068648_2069173_+	co-chaperone HscB	NA	NA	NA	NA
WP_011622514.1\|2069240_2071103_+	Fe-S protein assembly chaperone HscA	A0A0N9QXN8	Chrysochromulina_ericina_virus	1.5e-103	39.1
WP_011622515.1\|2071111_2071447_+	ISC system 2Fe-2S type ferredoxin	NA	NA	NA	NA
WP_011622516.1\|2071602_2072502_+	30S ribosomal protein S6--L-glutamate ligase	I3ULC9	Synechococcus_phage	3.2e-40	33.2
WP_011622517.1\|2072570_2072768_+	Fe-S cluster assembly protein IscX	NA	NA	NA	NA
WP_041408760.1\|2072965_2073133_+	hypothetical protein	NA	NA	NA	NA
WP_011622518.1\|2073353_2073785_+	nucleoside-diphosphate kinase	K7YW26	Megavirus	2.8e-18	40.9
WP_011622519.1\|2074098_2074542_+	Hsp20 family protein	A0A2L0V0Y9	Agrobacterium_phage	1.8e-20	49.5
WP_011622520.1\|2074673_2075168_-	acetolactate synthase small subunit	NA	NA	NA	NA
WP_011622521.1\|2075167_2076886_-	acetolactate synthase 3 large subunit	A0A0P0YLY7	Yellowstone_lake_phycodnavirus	2.8e-56	30.2

DBSCAN-SWA_4

2338641 : 2349938

uncultured_Caudovirales_phage(28.57%)

tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_011622729.1\|2338641_2341386_+	DNA translocase FtsK	A0A218M9A2	Mycobacterium_phage	4.2e-83	47.7
WP_011622730.1\|2341455_2342076_+	outer membrane lipoprotein chaperone LolA	NA	NA	NA	NA
WP_011622731.1\|2342084_2343416_+	replication-associated recombination protein A	G3MBE0	Bacillus_virus	1.1e-76	39.4
WP_011622732.1\|2343408_2343783_+	fluoride efflux transporter CrcB	A0A2H4PQR0	Staphylococcus_phage	3.5e-09	37.4
WP_011622733.1\|2343801_2345088_+\|tRNA	serine--tRNA ligase	A0A1B1IVT2	uncultured_Mediterranean_phage	9.8e-99	45.3
WP_011622734.1\|2345106_2345229_+	hypothetical protein	NA	NA	NA	NA
WP_011622735.1\|2345296_2345635_-	TusE/DsrC/DsvC family sulfur relay protein	NA	NA	NA	NA
WP_011622736.1\|2345628_2345910_-	sulfurtransferase complex subunit TusB	NA	NA	NA	NA
WP_011622737.1\|2345909_2346266_-	sulfurtransferase complex subunit TusC	NA	NA	NA	NA
WP_011622738.1\|2346280_2346673_-	sulfurtransferase complex subunit TusD	A0A2H4JA39	uncultured_Caudovirales_phage	1.5e-21	43.3
WP_011622739.1\|2346729_2347389_-	Bax inhibitor-1/YccA family protein	A0A2H4JFM9	uncultured_Caudovirales_phage	7.3e-34	43.9
WP_041408771.1\|2347648_2348551_-	LysR family transcriptional regulator	NA	NA	NA	NA
WP_011622741.1\|2348666_2349938_+	Bcr/CflA family multidrug efflux MFS transporter	S4TR35	Salmonella_phage	1.9e-17	22.6

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. NC_008321

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection