CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NC_008536	Candidatus Solibacter usitatus Ellin6076, complete sequence	14 crisprs	cas3,cas10,csm2gr11,csm3gr7,csm5gr7,DinG,csa3,cas4,RT,Cas9_archaeal,cas6	4	0	6	0

Results visualization

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CRISPR-Cas detection and classification

Crispr_ID: NC_008536_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_008536_1

11813-11947

Orphan

Consensus_repeat	Method
TGCTCGCAGGCCGCAAACATCCGCACCGGAATATTCGC	CRISPRCasFinder

1 spacers

The CRISPR arrays of NC_008536_1

>merge|NC_008536|1|11813-11947|CRISPRCasFinder
TGCTCGCAGGCCGCAAACATCCGCACCGGAATATTCGCACGCGTAACCCACGATTTCAATATGCGGCATACCGCCTGAGTATTACACTGCTCTTGTGTGCTCGTAGGCCGCAAACATCCGCACCGGAATATTCGC

>NC_008536|1|1|11813-11947|CRISPRCasFinder
TGCTCGCAGGCCGCAAACATCCGCACCGGAATATTCGC	ACGCGTAACCCACGATTTCAATATGCGGCATACCGCCTGAGTATTACACTGCTCTTGTG
TGCTCGTAGGCCGCAAACATCCGCACCGGAATATTCGC

Protein	Signature genes	Signature genes Name	Protein_function
NC_008536.1\|WP_011681800.1\|10982_11723_+\|class-I-SAM-dependent-methyltransferase	unknown	unknown	gnl\|CDD\|225136
NC_008536.1\|WP_011681804.1\|13559_17015_-\|DNA-polymerase-III-subunit-alpha	unknown	unknown	gnl\|CDD\|235554
NC_008536.1\|WP_011681808.1\|22889_23669_+\|ParA-family-protein	unknown	unknown	gnl\|CDD\|224113
NC_008536.1\|WP_011681801.1\|12210_12804_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|320683
NC_008536.1\|WP_011681807.1\|20990_22805_+\|tRNA-uridine-5-carboxymethylaminomethyl(34)-synthesis-enzyme-MnmG	unknown	unknown	gnl\|CDD\|235362
NC_008536.1\|WP_011681803.1\|13322_13550_-\|DUF433-domain-containing-protein	unknown	unknown	gnl\|CDD\|377269
NC_008536.1\|WP_041857217.1\|23643_24564_+\|ParB/RepB/Spo0J-family-partition-protein	unknown	unknown	gnl\|CDD\|275105
NC_008536.1\|WP_011681799.1\|9396_10986_+\|tetratricopeptide-repeat-protein	unknown	unknown	unknown
NC_008536.1\|WP_011681810.1\|24594_24975_-\|MerR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|133393
NC_008536.1\|WP_011681795.1\|2780_5228_+\|DNA-topoisomerase-(ATP-hydrolyzing)-subunit-B	unknown	unknown	gnl\|CDD\|237860
NC_008536.1\|WP_011681805.1\|17147_19577_-\|ABC-transporter-permease	unknown	unknown	gnl\|CDD\|274576
NC_008536.1\|WP_011681794.1\|1636_2755_+\|DNA-polymerase-III-subunit-beta	unknown	unknown	gnl\|CDD\|235541
NC_008536.1\|WP_011681798.1\|8626_9400_+\|redoxin-domain-containing-protein	unknown	unknown	gnl\|CDD\|239266
NC_008536.1\|WP_011681793.1\|88_1402_+\|chromosomal-replication-initiator-protein-DnaA	unknown	unknown	gnl\|CDD\|273037
NC_008536.1\|WP_011681806.1\|19775_20984_-\|phosphoribosylamine--glycine-ligase	unknown	unknown	gnl\|CDD\|234856
NC_008536.1\|WP_041857215.1\|6843_8478_-\|M20/M25/M40-family-metallo-hydrolase	unknown	unknown	gnl\|CDD\|349910
NC_008536.1\|WP_011681796.1\|5231_6827_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|275303
NC_008536.1\|WP_011681802.1\|12822_12996_+\|CPXCG-motif-containing-cysteine-rich-protein	unknown	unknown	gnl\|CDD\|379524

Protein	Function_ID	Function_description	E-value
NC_008536.1\|WP_011681800.1\|10982_11723_+\|class-I-SAM-dependent-methyltransferase	gnl\|CDD\|225136	COG2226, UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis [Coenzyme metabolism].	3.32767e-27
NC_008536.1\|WP_011681804.1\|13559_17015_-\|DNA-polymerase-III-subunit-alpha	gnl\|CDD\|235554	PRK05673, dnaE, DNA polymerase III subunit alpha; Validated.	0
NC_008536.1\|WP_011681801.1\|12210_12804_+\|hypothetical-protein	gnl\|CDD\|320683	cd07324, M48C_Oma1-like, Oma1 peptidase-like, integral membrane metallopeptidase. This family contains peptidase M48 subfamily C (also known as Oma1 peptidase or mitochondrial metalloendopeptidase OMA1), including similar peptidases containing tetratricopeptide (TPR) repeats, as well as uncharacterized proteins such as E. coli bepA (formerly yfgC), ycaL and loiP (formerly yggG), considered to be putative metallopeptidases. Oma1 peptidase is part of the quality control system in the inner membrane of mitochondria, with its catalytic site facing the matrix space. It cleaves and thereby promotes the turnover of mistranslated or misfolded membrane proteins. Oma1 can cleave the misfolded multi-pass membrane protein Oxa1, thus exerting a function similar to the ATP-dependent m-AAA protease for quality control of inner membrane proteins. It has been proposed that in the absence of m-AAA protease, proteolysis of Oxa1 is mediated by Oma1 in an ATP-independent manner. Homologs of Oma1 are present in higher eukaryotes, eubacteria and archaebacteria, suggesting that Oma1 is the founding member of a conserved family of membrane-embedded metallopeptidases, all containing the zinc metalloprotease motif (HEXXH). M48 peptidases proteolytically remove the C-terminal three residues of farnesylated proteins.	0.000837316
NC_008536.1\|WP_011681807.1\|20990_22805_+\|tRNA-uridine-5-carboxymethylaminomethyl(34)-synthesis-enzyme-MnmG	gnl\|CDD\|235362	PRK05192, PRK05192, tRNA uridine-5-carboxymethylaminomethyl(34) synthesis enzyme MnmG.	0
NC_008536.1\|WP_011681803.1\|13322_13550_-\|DUF433-domain-containing-protein	gnl\|CDD\|377269	pfam04255, DUF433, Protein of unknown function (DUF433).	4.46506e-17
NC_008536.1\|WP_041857217.1\|23643_24564_+\|ParB/RepB/Spo0J-family-partition-protein	gnl\|CDD\|275105	TIGR04285, parB-like_partition_protein, nucleoid occlusion protein. This model describes nucleoid occlusion protein, a close homolog to ParB chromosome partitioning proteins including Spo0J in Bacillus subtilis. Its gene often is located near the gene for the Spo0J ortholog. This protein bind a specific DNA sequence and blocks cytokinesis from happening until chromosome segregation is complete.	3.03433e-67
NC_008536.1\|WP_011681808.1\|22889_23669_+\|ParA-family-protein	gnl\|CDD\|224113	COG1192, Soj, ATPases involved in chromosome partitioning [Cell division and chromosome partitioning].	2.5115e-84
NC_008536.1\|WP_011681810.1\|24594_24975_-\|MerR-family-transcriptional-regulator	gnl\|CDD\|133393	cd04765, HTH_MlrA-like_sg2, Helix-Turn-Helix DNA binding domain of putative MlrA-like transcription regulators. Putative helix-turn-helix (HTH) MlrA-like transcription regulators (subgroup 2), N-terminal domain. The MlrA protein, also known as YehV, has been shown to control cell-cell aggregation by co-regulating the expression of curli and extracellular matrix production in Escherichia coli and Salmonella typhimurium. These proteins belong to the MerR superfamily of transcription regulators that promote expression of several stress regulon genes by reconfiguring the spacer between the -35 and -10 promoter elements. Their conserved N-terminal domains contain predicted HTH motifs that mediate DNA binding, while the dissimilar C-terminal domains bind specific coactivator molecules.	2.60249e-40
NC_008536.1\|WP_011681795.1\|2780_5228_+\|DNA-topoisomerase-(ATP-hydrolyzing)-subunit-B	gnl\|CDD\|237860	PRK14939, gyrB, DNA gyrase subunit B; Provisional.	0
NC_008536.1\|WP_011681805.1\|17147_19577_-\|ABC-transporter-permease	gnl\|CDD\|274576	TIGR03434, ADOP, Acidobacterial duplicated orphan permease. Members of this protein family are found, so far, only in three species of Acidobacteria, namely Acidobacteria bacterium Ellin345, Acidobacterium capsulatum ATCC 51196, and Solibacter usitatus Ellin6076, where they form large paralogous families. Each protein contains two copies of a domain called the efflux ABC transporter permease protein (pfam02687). However, unlike other members of that family (including LolC, FtsX, and MacB), genes for these proteins are essentially never found fused or adjacent to ABC transporter ATP-binding protein (pfam00005) genes. We name this family ADOP, for Acidobacterial Duplicated Orphan Permease, to reflect the restricted lineage, internal duplication, lack of associated ATP-binding cassette proteins, and permease homology. The function is unknown.	0
NC_008536.1\|WP_011681794.1\|1636_2755_+\|DNA-polymerase-III-subunit-beta	gnl\|CDD\|235541	PRK05643, PRK05643, DNA polymerase III subunit beta; Validated.	7.48624e-149
NC_008536.1\|WP_011681798.1\|8626_9400_+\|redoxin-domain-containing-protein	gnl\|CDD\|239266	cd02968, SCO, SCO (an acronym for Synthesis of Cytochrome c Oxidase) family; composed of proteins similar to Sco1, a membrane-anchored protein possessing a soluble domain with a TRX fold. Members of this family are required for the proper assembly of cytochrome c oxidase (COX). They contain a metal binding motif, typically CXXXC, which is located in a flexible loop. COX, the terminal enzyme in the respiratory chain, is imbedded in the inner mitochondrial membrane of all eukaryotes and in the plasma membrane of some prokaryotes. It is composed of two subunits, COX I and COX II. It has been proposed that Sco1 specifically delivers copper to the CuA site, a dinuclear copper center, of the COX II subunit. Mutations in human Sco1 and Sco2 cause fatal infantile hepatoencephalomyopathy and cardioencephalomyopathy, respectively. Both disorders are associated with severe COX deficiency in affected tissues. More recently, it has been argued that the redox sensitivity of the copper binding properties of Sco1 implies that it participates in signaling events rather than functioning as a chaperone that transfers copper to COX II.	1.71103e-41
NC_008536.1\|WP_011681793.1\|88_1402_+\|chromosomal-replication-initiator-protein-DnaA	gnl\|CDD\|273037	TIGR00362, DnaA, chromosomal replication initiator protein DnaA. DnaA is involved in DNA biosynthesis; initiation of chromosome replication and can also be transcription regulator. The C-terminal of the family hits the pfam bacterial DnaA (bac_dnaA) domain family. For a review, see Kaguni (2006). [DNA metabolism, DNA replication, recombination, and repair].	0
NC_008536.1\|WP_011681806.1\|19775_20984_-\|phosphoribosylamine--glycine-ligase	gnl\|CDD\|234856	PRK00885, PRK00885, phosphoribosylamine--glycine ligase; Provisional.	0
NC_008536.1\|WP_011681802.1\|12822_12996_+\|CPXCG-motif-containing-cysteine-rich-protein	gnl\|CDD\|379524	pfam14255, Cys_rich_CPXG, Cysteine-rich CPXCG. This family of proteins is found in bacteria. Proteins in this family are approximately 60 amino acids in length. There are 5 conserved cysteines which occur in a CPXCG motif and a DCXXCCXP motif.	2.41116e-13
NC_008536.1\|WP_011681796.1\|5231_6827_-\|hypothetical-protein	gnl\|CDD\|275303	TIGR04510, mod_pep_cyc, putative peptide modification system cyclase. Members of this family show homology to mononucleotidyl cyclases and to tetratricopeptide repeat (TPR) proteins. Members occur in next to two other markers of ribosomal peptide modification systems. One is a dehydrogenase related to SagB proteins from thiazole/oxazole modification systems. The other is the putative precursor, related to the nitrile hydratase-related leader peptide (NHLP) and nitrile hydratase alpha subunit families. These systems occur in many species of Xanthomonas and Stenotrophomonas, among others.	0.00516092
NC_008536.1\|WP_041857215.1\|6843_8478_-\|M20/M25/M40-family-metallo-hydrolase	gnl\|CDD\|349910	cd05660, M28_like_PA, M28 Zn-peptidase containing a protease-associated (PA) domain insert. Peptidase family M28 (also called aminopeptidase Y family), uncharacterized subfamily. The M28 family contains aminopeptidases as well as carboxypeptidases. They have co-catalytic zinc ions; each zinc ion is tetrahedrally co-ordinated, with three amino acid ligands plus activated water; one aspartate residue binds both metal ions. This subfamily is composed of uncharacterized proteins containing a protease-associated (PA) domain insert which may participate in substrate binding and/or promote conformational changes, influencing the stability and accessibility of the site to substrate.	3.69548e-86

>NC_008536.1|WP_011681800.1|10982_11723_+|class-I-SAM-dependent-methyltransferase
MTPDPKQQISDTYTAAADSFEAPPLAFWQRFGERTVERAQLSPGAIVLDVCCGAGGSAIPAARAVAPSGRVIGVDLAPGLLNLARAKAVPNAEFRHADFEQVYFRPATFDAVVCVFGIFFFEDMSAALQKMWRFLRPGGTLAITVWGPSAFAPLDGIFPGPHRWTRLAEPGSVEKLFADSGIPGAEITYEDYSQSLASPEDWWTIVNGSGFRGKVTPDAKDSLRAACLAIPSLSVPLPVTYALVRR
>NC_008536.1|WP_011681799.1|9396_10986_+|tetratricopeptide-repeat-protein
MKFAVLCTLVLAALAQQPKGADNCAPPPSSLAPTLPARILPGMGTVHLAITTSSPEAQQFFDQGLAQMHSFWAREAERSFLQAAALDPAAPMPQWGIAMVAAGDWRPRFQIDTLGAFFGKQVAPATSRARIAAKKAVELAAVPGKATDLEKLYVAAIAARRDPDAKDPEEAFVKGLRTLLAAHPGEVEAELDLALMIMRGFTLPDKKPTAPGSTEAVAILRSLLPRVPEHPGLHHYIIHGFEGSTFAKDAWPSCEKYSQLVTNIPHALHMPGHIYSQTGRWTDAEKSFADAAANERKWMSLDKLYGDGHHGHNVHYLATAYSFEGRYDDAIEAAKELLAFKENPAQQSAPDGVGSARAQGWFAMLRTLVQFEKWDAILQGEMLPVFGRARQDAWRHWAFALAYANTGKPAAAHEEAAKFDQSLADFRARTKRPNPTELEVARFEMLAHLELADGRVDRALKQFQIASAAERRLVYTEPPYYPRPVGEPWGRAAQKANKTKLAQRAFQIALEQYPNDSHAKAATVVSQIR
>NC_008536.1|WP_011681798.1|8626_9400_+|redoxin-domain-containing-protein
MPNLLSTLVLFAHTYPVDGIVVAVDPQARTMLVSHRPIPHYMPAMMMPFRVENPAVLQPLHPGARITFDLAVTKSQALARNVRATGDPDAALPAPPQKLAIGAPLPEFALTDQHGRTVTPADFRGQIVAIDFIYSRCPLPDVCPRLSANFAMLQRRFGANITLLSVTVDPDYDTPAVLADYARRWSAGPAWHFLTGDVAPLAAALGEIYWAGEGSIGHNSTTCIIDRTGRLAAVIEGSNYRPDQLVNLISRQLETHP
>NC_008536.1|WP_041857215.1|6843_8478_-|M20/M25/M40-family-metallo-hydrolase
MKRLALLLGAATLFAADYAAEGDRWWAHIAFLADDKLQGRDVGSDGFKEAAKYVAGKMETYGLKPAGTSGYYQPVKFETRQLVEDETSLTLVRDGKAETLDRADATLSTRADLAPVVEAGMVFVGYGLKVPEAKYDDLAGMDLRGKIAVYVNSTGALDAPGPVKSHVGSGSERWKVLQAAGAIGTATIMNPRPSAVSVTPLPGDAAAGGGRGQGGRGAGGGAGRGPQKSFLLADPELQEATGQKVALTITRTGGPKFFEGSGYTMDEILKLAMDNKPLPHFEINGKLISKAVMKRESVEAPNVAGMLPGSDPKLKNEYVIMSAHLDHVGVGRAVNGDNIYNGAMDDASGIASILEIARIMKESGAKPRRSILFLAVTAEEKGELGSRYFAMRPTVDRKQIVADINLDMFMPLFELKWIEVQGLAESTLGDTVRAAAKEYGVQVQADKEPDQNRFVRSDQYSFIRNGVPSLAFKFGYEFGTPEDKIFHDWVRDRYHKPSDDLNQPVDKASAAKFDRVIVSLLQMVADAPARPQWKDDSFFKRFAK
>NC_008536.1|WP_011681796.1|5231_6827_-|hypothetical-protein
MRRVILFLVCAGAGLAQHEMGKPQEKPVALYPGLGNWRHPIATRNAEAQRYFDQGLALLYGFNRYEALRSFRKASELDPAGAMPYWGMAMSTGPYINMGAEGDGDLDSKAACAAAANGLKVAGAPARERAYVEAAAARCPEYKPEAYIAAMKALAESYPDDLDAATLYAESLMVPVRWHWYTADGKAAPGMSEAERTLEQVLRRWPSHPGANHYYIHAVESSPTPERAIPSAQQLMGVVPWAGHIVHMPGHIWLALGDYELAASLNERASAVDREYFAATNVVGAYNMYYVHNLHFVAYARSMQGQRAATVKAANAMAQAGAPLADMMPEMADGFLSMPLLVKVRVQAWDEVLKAPQPAGTMVAQTAMWHYARMMAMLGTGNRAGAAAERDAFEAARKKVPADRPWGTNNSCGDVMAMVEEIVAARMSAEDIGHWEKAVALQDALVYDEPPAWYYPLRESLGAALVKAGRAADAEKVFREGLRRSPRDAWMIFGLMESVKAQKKSEGIAELQHELDAAWGTADVKQALQGM
>NC_008536.1|WP_011681795.1|2780_5228_+|DNA-topoisomerase-(ATP-hydrolyzing)-subunit-B
MPNEVNPVGGNGNVYDSSSIKVLEGLEAVRLRPAMYIGSTGEMGLHHLVYEVVDNSVDEALAGYATHIEVTIHDDNSVTVEDDGRGIPVGIHEEEGVSAAQVVMTKLHAGGKFDSNSYKVSGGLHGVGVSCVNALSEKLELEIWREGYTWTQEYSCGKPKADLVRAGKAGKRTGTRVTFKPDSTIMEVAVFNYDTLAQRLRELAFLNKGLKITLTDERVDPEKVTPFEYQGGISEFIKHLNRGKSVLHEKPIHFEAEREMPEKGTITMEVALQYNDAYSENVFSFANNINTVDGGTHLSGFRSALTRTINAFGQKNGLFKDVKENLSGDDVREGLTAVVSVKVPQPQFEGQTKGKLNSDIAGYMTQFVNDKLSEYFDKNSAVGRKIVGKAIEASRAREAARKARDLTRRKGALDSGGLPGKLADCQEKDPKLCELFLVEGESAGGTAKQGRERRFQAILPLKGKILNVEKARYDKMLGHEEIRCMITALGTGIGKDDFDVAKLRYDKIIIMTDADVDGSHIRTLLLTFFFRHMNELITRGKVYIAQPPLYRIKKGKSEKYIKDEKEFTKEIMRRATENLTVEIHSNGDGKPKSSLEGQELRTFLLNLDEFQQIFHKVERRLRDSRAVDVLTNVDLHVDNKAEFQVEANLKPVFEAMKAKGLNPQMKKDEEHSAWAVVFHDSTGAERSVGLQLAAQPEYRRFRALARTIAKFNEPPFVVVKNEHRDAQPDWVELLEYVKNEGKKDASVQRYKGLGEMNAEQLADTTMNPEKRTLLEVRLEDAVQCEEIFSTLMGEDVESRRKFIEENALDVKNLDV
>NC_008536.1|WP_011681794.1|1636_2755_+|DNA-polymerase-III-subunit-beta
MEFTVSKSDLVRELSLSQGVVEKKTTIPILSNVLLEAADDRITLTATDLELGIRCSCPARVKKEGSGTVPARKLLDYMRLLPEGDVNMKFLDNHWASITSGRSRTRIAGMSRESFPELPQMPEPIAQVPVKTLASMIARTSFAISMEESRFTLNGALLLMRPEGLTMVATDGHRLAYVQAEPAESGSADKPFRALVPKKAMSELTKLSDDAGEGAMAIVAGDDNHLFFQIGHRLLITRKLTGNFPDYERVLPKDHQFMAKLEKGEIRSAIERVAQFADERSRAIRVQFNSGEVRVFSSSVETGESEESVPAEYTGPDIEIGFNAQYLLDFLRAISQDHVAFELKDQKSAGELRPAGDAIADQYRYVVMPMRI
>NC_008536.1|WP_011681793.1|88_1402_+|chromosomal-replication-initiator-protein-DnaA
MNYWDQIRHYLQSKVSADGYDNWLKSTAFVGQNGDTLYVSVPDRETRAWLETEYTQLIQGGIQALGLPVRHVSFEAEQSRPAAPAATIAVNANTEPDAAATVLNPKFTFNSFVVGACNQFAHAAAKSVATNPSRSYNPLFLYGGVGMGKTHLMHAIGRQLIDQFGSMRIIYTSSERFMNEMISCIRTERMQQFHQRYREADVLLIDDIQLLGNKERTQEEFFHTFNELHDHQKQIVISSDSPPKDIPGLLERLRSRFEWGLMADIQPPDLETKMAILDKKAEIEGVELPDDVRTFMASKTKSNVRELEGALVKLIAYSSLTGTPIHLQMAQQVLKHLVHVQDRRVTMDSIQKAVAEKFSIKQSQLKEKSNTKKVVYPRQVAMYLVKELTNASLPEIGRAFGGKHHTTVIHSINKIEKDRQSDPELNRLLHSLMDSLQ
>NC_008536.1|WP_011681801.1|12210_12804_+|hypothetical-protein
MCNSILRILLATFLMFPKLYAGDAKCNLPVVTIYVNEKVNLPLKQRARAIFVATRAFREIGVQLNWRDGAVPPDPQSPSCARADIIELQVDQAADADRPPDSLAYAIAGSSSGPRIHVFLDRVDAFSAPVPNLFGYVLAHEIAHVLQGMARHSEDGILKARWRGRDYNRMATLSLRFSREDADRIAYYLTHQHRPTE
>NC_008536.1|WP_011681802.1|12822_12996_+|CPXCG-motif-containing-cysteine-rich-protein
MEHFFVCPYCGERISMVLDTSVKGQTYVEDCEVCCQPIEVRYTVKDDEVRNFEARTL
>NC_008536.1|WP_011681803.1|13322_13550_-|DUF433-domain-containing-protein
MDWSRCGAVDRSAEKLGGRWCFRGTRLPVAALFEHLDQGSTIDEFLEWFPAVCREQVHEVLAFAKDSLEQPAAVA
>NC_008536.1|WP_011681804.1|13559_17015_-|DNA-polymerase-III-subunit-alpha
MSFVHLHCHTDYSLLDGACDIDQLMKIMVEQKMPAVAMTDHGNLFGAVKFYNAAKASGIHPVIGCEVYVSQKGHKERTNTDRYNHLVLLCENQQGYKNLIKLVSTSYLEGFYYKPRIDLDLLSQHSEGLIGMSACLRGHIPETILNDKYDDARRMAHQYGDIFGAKNFFLEIQDHHLEQDKRLTPELVRLSSETGFPLVATNDSHYLRKDDARAHEILMCIQTGKSFNDPNRMRWSTPDFYLKTREEMMQLFGELEHSLDRTWEIAQRCHVKLEKVLDPFPRFDIPTEHTTDTYFEYVARMGFEKRRGRLEAMKAKGTLKHDLEEYAERLDREIKMIQNMKFSGYFLVVWDFIRYAKDQGIPVGPGRGSAAGSLVSYAMEITDIDPLQYGLLFERFLNPERVSFPDVDVDFCMNRRGEVIQYVTQKYGREQVAQIITFNTLGARAAIKDVGRVLEMPLPEVERLTKLVPATLNISLQEAIDQEPGFKEAARKDPRCDDVLKVALRLEGLSRNCSVHAAGVVISPLPLQDLVPLYKTNRDEIVTQFDMGGLEKLQLLKMDFLGLTTLTLIQDALRLIKKRHGVTIVPEDLPLDDKGTYEVFCKGITSGVFQFESSGMRDILRRYQPSRLEDLTALNALYRPGPIQGGMVDDFIERKWGRKAVQYDLPELQVLLEETYGVIVYQEQVMQISNRIAGYSLGDADLLRRAMGKKKLEEMVKQRERFVKGALERGFNQKKVEKIFDLMEQFAGYGFNKSHSAAYAYLAFVTAYLKAHYPVDFMAALLTSETGNTAKVVKYINECREMGIKILPPDVNHSEWSFTPDGDAIRFGMGAIKNVGQSAVEAIGKTRAEVGKFPSLHEFCEKVDLGAVNRRMIESLIRAGAMDSLEGTRSQKFAAVEGAMEAGARAQRDRESGQVGLFGEVIAADEPHSAPLPNIPDWSEKEKLAGEKELLGFWVTGHPMDRYMEKVAELANADTSSLEGLAKNHEVAICGVLTGIARKRNREGKPWCAMTLEDRAGSVEALLFATNYERLASQAVEDTVVLMRALVLPEEGTNPKLSVQDIVALDNARIDMPSVIAIRVWLGRNGGVDRAAALEELFKRKPGPTSVRLRLEAPRDFSILIDVEAKVRPDREFKAAVEQICGPECVEKVAG
>NC_008536.1|WP_011681805.1|17147_19577_-|ABC-transporter-permease
MQSLWQDLRYGLRGMRSNPGFTALAMATLALGIGAGTTMFSVIKNVLISPFPYKEAERIAAFRIHDLDSGRPGGRSFFKAADYREFRRGNHVFSEDTGGGNEDVLWTTPEGTEQFDGGYLTPNSFDFLGVAPLVGRGINVEDGKPGAPPVFVMSYKMWMKRFSGDPKILGRSFVLNGTPTTLVGIMPKRFTKRGADLWVAADLDPTSERYFLFQGRMKPGVTLKQVEADLMPIAQRLAQANPKEYPKRFSIEASSYVDSIVGPFKKTLLTLSAAVALLLFIACANVANMLLARSTARDREMAIRSALGASRWRVVRQLLVESVLLGIGGAVLGCALAYGGIKALVALIPEGAIPQEAEIGLDPQALWFSLALAVCTALVFGLAPALQTARRDIVEPLKDSGRGVSGGFRRGRLRNALVVVELALSLVLLTGAGVMIRTFVKLTSTDLGFDAKNILVARLPFPKDQYKTVAEKQRFFSQLLPRLKALPGVVEATTTSGLPPYGGIGTDIEIAGKQHTDRWRAEYQLVSEGYLRTLRGKVVRGRMLDEGDVAGARKVAVINQTLAAKWFLHEDPLGHQVRLLRNVSDGGGAVAGATQPYYEIVGIMSDMKNSGLQDPTEPELLVPYTSTGSFERGILVRTAGKPLAMLNAVRREVWAVDRNVSTTMTRSLEDFLSDFSYAQPRFTLLVLGVFAGCGLLLVAIGVYSVIAYTVSRQTHEIGIRVALGASRGDVIGMVVKMGMWLIALGLGVGLAVSLAVSKVLSSELFGVSARDPLTFALVSLVVLAAGAAACWVPAMKATRIDPMVALRFE
>NC_008536.1|WP_011681806.1|19775_20984_-|phosphoribosylamine--glycine-ligase
MKILVIGSGGREHALCWKLAQSPGVEVFANPGNPGMALVATCIPGEALDAALAIRADLTVVGPEVPLVAGVVDAFRAQGLKIVGPDAEAAQLEGSKIFAKNFFMKSGIPTARYEAVDDPQQARAALSRFGFPVVLKADGLAAGKGVIIAQNAAEADAALETLKGAIVVEEFLTGQEVSFIALCDGKDALPLAATQDHKAVFDGDRGPNTGGMGAYCASGILSDADCQMVMERVIYPTVRAMNFTGFLYAGLMMTTEGPRVLEFNVRLGDPETQPLMHRMKSDFVPALMAAAEGRLAGHTLEWNAGPSVCVVMTSAGYPGTFEAGKEILGVEQAEAHGAVVFQAGTRLLHGRLETAGGRVLGVTASGADLPAAIGMAYEAVAKIQFEGMHYRHDIARKGIIRG
>NC_008536.1|WP_011681807.1|20990_22805_+|tRNA-uridine-5-carboxymethylaminomethyl(34)-synthesis-enzyme-MnmG
MVAMPERYDVVVIGAGHAGCEAARACARIGLRTAMVTMNLDLIAQMSCNPAIGGIAKGHLVREIDALGGVMGEVADSVGIQFRLLNTSRGPAVWSPRAQMDKKLYRFRMREVLEAEPNLRIKQAEVAALTFDAVRRVNGVLLRDGRTIPAGAVIVTTGTFLNGLAHVGEMTYSCGRNGEAPSQLLGDQLRSMGLNWTRLKTGTPPRLDGRSIDWSSFEPQAGDAEPTPFSFLTGRIERQQIQCHIGYTTDETRRVLQEAIPRSPLYSGQIEGVGPRYCPSIEDKFVKFPDKVRHQIFLEPEGLDTHEVYVNGMSTSMPTDVQVAMVASIPGLEQAEMIRPGYAIEYDAIDPRELNHTLEVKSIPGLYLAGQINGTSGYEEAGIQGLIAGLNAAMSLGGSDPVIIGRTEGYAGILVDDLITKGADEPYRMFTSRAEFRLHLRIDNADARLTPLGRRAGLATDERWELFQRKERQKLRLTQAFETHKNGQLLKRPEVSISDFLPWIVEVLGEAPCRGLLETVSTEAKYGGYIQQQERQMARMKDSERRAIPHGFEYRGIPGLSREIQDKLDKVRPGTLGQAGRVPGVTPAAIAVLDCYLSLHIGPN
>NC_008536.1|WP_011681808.1|22889_23669_+|ParA-family-protein
MSRVFAIANQKGGVGKTTTAINLAASLAANDIRVLVIDSDPQGNCTSGLGVTKDPDKPSLYHVLLGDSHMKDAIRPTDFEGLQIITADKNLVGSNLEMVDLPNREFLLRTRINEIRKNYEFILIDCPPALDLLTLNALLAADSVLVPIQCEFFALEGISELMDTIERIRESFHHPLEVEGILLTMFDDRTNLTRQVATDLRDFFKDQVFKTVIPRSVRLAEAPSFGKPILTYDPRSRGAESYIKLAKEILDHAKNRQPA
>NC_008536.1|WP_041857217.1|23643_24564_+|ParB/RepB/Spo0J-family-partition-protein
MQKTDNPRRALGKGIGALLPTRTPAPPPVAPPPPAAEKPELPENAELTLFIDPALIDANPLQPRRVFAQEPLAELAQSIRSNGIIQPLVVTRKGDRYQLVAGERRWRASKLAEVATVPVVVRDIPEGRLLEITLIENIQREDLNAIETADAFARMTSELHMSADQIGLRTGKDRSTIVNFMRLLQLPADVQALVSENKLSAGHGRCLLKLPNAVVQREVAKKALAEGWSVRQMERVCAKIADPVAPKAVEEAKLDPNVKAAIDEMQRRLGTKIHVKEGARGRGKLEIEYYSADDLTRIYDVIMGES
>NC_008536.1|WP_011681810.1|24594_24975_-|MerR-family-transcriptional-regulator
MTDVALQPTPEIPDKLYFKIGEVSELLGVEAYVLRYWESEFPVLSPKKSGTGHRLYRRKDVELLLRIKHLLYEKRFTIEGARQTLQSEAKAPKPARVPKRVQAELFSEDPLPEIRRELRDILELLK

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Crispr_ID: NC_008536_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_008536_2

122569-122656

Orphan

Consensus_repeat	Method
CCGGTGACCTAACTTAGGTCACCT	CRISPRCasFinder

1 spacers

The CRISPR arrays of NC_008536_2

>merge|NC_008536|2|122569-122656|CRISPRCasFinder
CCGGTGACCTAACTTAGGTCACCTGGTTTTGGCATGTTGCTGATTTCAAATGGCGTCAATTTTCCCGGTGACCTGACTTAGGTCACCT

>NC_008536|2|2|122569-122656|CRISPRCasFinder
CCGGTGACCTAACTTAGGTCACCT	GGTTTTGGCATGTTGCTGATTTCAAATGGCGTCAATTTTC
CCGGTGACCTGACTTAGGTCACCT

Protein	Signature genes	Signature genes Name	Protein_function
NC_008536.1\|WP_011681885.1\|127986_129822_-\|4Fe-4S-ferredoxin	unknown	unknown	gnl\|CDD\|223717
NC_008536.1\|WP_157675047.1\|114998_115535_-\|hypothetical-protein	unknown	unknown	unknown
NC_008536.1\|WP_011681888.1\|132585_134412_-\|peptidase-M56,-BlaR1	unknown	unknown	gnl\|CDD\|320700
NC_008536.1\|WP_011681887.1\|132218_132584_+\|hypothetical-protein	unknown	unknown	unknown
NC_008536.1\|WP_011681886.1\|129818_132029_-\|acyl-CoA/acyl-ACP-dehydrogenase	unknown	unknown	gnl\|CDD\|224871
NC_008536.1\|WP_011681871.1\|111049_111973_+\|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|224054
NC_008536.1\|WP_011681882.1\|124014_125736_+\|Omp28-related-outer-membrane-protein	unknown	unknown	gnl\|CDD\|369071
NC_008536.1\|WP_011681876.1\|116687_117692_+\|hypothetical-protein	unknown	unknown	unknown
NC_008536.1\|WP_011681884.1\|126484_127969_+\|carboxylesterase-family-protein	unknown	unknown	gnl\|CDD\|365897
NC_008536.1\|WP_157675048.1\|126236_126407_+\|hypothetical-protein	unknown	unknown	unknown
NC_008536.1\|WP_011681883.1\|125732_126203_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|378661
NC_008536.1\|WP_011681879.1\|120685_121687_-\|electron-transfer-flavoprotein-subunit-alpha	unknown	unknown	gnl\|CDD\|224936
NC_008536.1\|WP_063720780.1\|119652_120537_-\|alpha/beta-hydrolase	unknown	unknown	gnl\|CDD\|223669
NC_008536.1\|WP_011681890.1\|135454_136426_+\|hypothetical-protein	unknown	unknown	unknown
NC_008536.1\|WP_011681880.1\|121688_122501_-\|electron-transfer-flavoprotein-subunit-beta	unknown	unknown	gnl\|CDD\|224997
NC_008536.1\|WP_011681875.1\|115512_116607_-\|phosphatidylserine/phosphatidylglycerophosphate/-cardiolipin-synthase-like-protein	unknown	unknown	gnl\|CDD\|197225
NC_008536.1\|WP_011681877.1\|117790_119605_-\|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|224055
NC_008536.1\|WP_011681889.1\|134398_134800_-\|BlaI/MecI/CopY-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|367747
NC_008536.1\|WP_011681873.1\|114048_115002_-\|metallophosphoesterase	unknown	unknown	gnl\|CDD\|277324
NC_008536.1\|WP_011681872.1\|111969_114162_+\|amidohydrolase-family-protein	unknown	unknown	gnl\|CDD\|238624

Protein	Function_ID	Function_description	E-value
NC_008536.1\|WP_011681885.1\|127986_129822_-\|4Fe-4S-ferredoxin	gnl\|CDD\|223717	COG0644, FixC, Dehydrogenases (flavoproteins) [Energy production and conversion].	8.1546e-16
NC_008536.1\|WP_011681877.1\|117790_119605_-\|ABC-transporter-ATP-binding-protein	gnl\|CDD\|224055	COG1132, MdlB, ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms].	0
NC_008536.1\|WP_011681888.1\|132585_134412_-\|peptidase-M56,-BlaR1	gnl\|CDD\|320700	cd07341, M56_BlaR1_MecR1_like, Peptidase M56-like including those in BlaR1 and MecR1, integral membrane metallopeptidase. This family contains peptidase M56, which includes zinc metalloprotease domain in MecR1 as well as BlaR1. MecR1 is a transmembrane beta-lactam sensor/signal transducer protein that regulates the expression of an altered penicillin-binding protein PBP2a, which resists inactivation by beta-lactam antibiotics, in methicillin-resistant Staphylococcus aureus (MRSA). BlaR1 regulates the inducible expression of a class A beta-lactamase that hydrolytically destroys certain ?-lactam antibiotics in MRSA. Both, MecR1 and BlaR1, are transmembrane proteins that consist of four transmembrane helices, a cytoplasmic zinc protease domain, and the soluble C-terminal extracellular sensor domain, and are highly similar in sequence and function. The signal for protein expression is transmitted by site-specific proteolytic cleavage of both the transducer, which auto-activates, and the repressor, which is inactivated, unblocking gene transcription. All members contain the zinc metalloprotease motif (HEXXH). Homologs of this peptidase domain are also found in a number of other bacterial genome sequences, most of which are as yet uncharacterized.	1.25787e-33
NC_008536.1\|WP_011681886.1\|129818_132029_-\|acyl-CoA/acyl-ACP-dehydrogenase	gnl\|CDD\|224871	COG1960, CaiA, Acyl-CoA dehydrogenases [Lipid metabolism].	3.25886e-19
NC_008536.1\|WP_011681871.1\|111049_111973_+\|ABC-transporter-ATP-binding-protein	gnl\|CDD\|224054	COG1131, CcmA, ABC-type multidrug transport system, ATPase component [Defense mechanisms].	6.06186e-94
NC_008536.1\|WP_011681882.1\|124014_125736_+\|Omp28-related-outer-membrane-protein	gnl\|CDD\|369071	pfam06764, DUF1223, Protein of unknown function (DUF1223). This family consists of several hypothetical proteins of around 250 residues in length which are found in both plants and bacteria. The function of this family is unknown. Structurally it lies in the Thioredoxin-like superfamily.	4.55228e-06
NC_008536.1\|WP_011681884.1\|126484_127969_+\|carboxylesterase-family-protein	gnl\|CDD\|365897	pfam00135, COesterase, Carboxylesterase family.	1.54212e-117
NC_008536.1\|WP_011681883.1\|125732_126203_+\|hypothetical-protein	gnl\|CDD\|378661	pfam11412, DsbC, Disulphide bond corrector protein DsbC. DsbC rearranges incorrect disulphide bonds during oxidative protein folding. It is activated by the N-terminal domain of DsbD, a transmembrane electron transporter. DsbD binds to a DsbC dimer and selectively activates it using electrons from the cytoplasm.	6.75815e-17
NC_008536.1\|WP_011681879.1\|120685_121687_-\|electron-transfer-flavoprotein-subunit-alpha	gnl\|CDD\|224936	COG2025, FixB, Electron transfer flavoprotein, alpha subunit [Energy production and conversion].	5.25296e-15
NC_008536.1\|WP_063720780.1\|119652_120537_-\|alpha/beta-hydrolase	gnl\|CDD\|223669	COG0596, MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [General function prediction only].	1.70774e-18
NC_008536.1\|WP_011681880.1\|121688_122501_-\|electron-transfer-flavoprotein-subunit-beta	gnl\|CDD\|224997	COG2086, FixA, Electron transfer flavoprotein, beta subunit [Energy production and conversion].	5.16647e-10
NC_008536.1\|WP_011681875.1\|115512_116607_-\|phosphatidylserine/phosphatidylglycerophosphate/-cardiolipin-synthase-like-protein	gnl\|CDD\|197225	cd09127, PLDc_unchar1_1, Putative catalytic domain, repeat 1, of uncharacterized phospholipase D-like proteins. Putative catalytic domain, repeat 1, of uncharacterized phospholipase D (PLD, EC 3.1.4.4)-like proteins. PLD enzymes hydrolyze phospholipid phosphodiester bonds to yield phosphatidic acid and a free polar head group. They can also catalyze transphosphatidylation of phospholipids to acceptor alcohols. Members of this subfamily contain two HKD motifs (H-x-K-x(4)-D, where x represents any amino acid residue) that characterizes the PLD superfamily. The two motifs may be part of the active site and may be involved in phosphatidyl group transfer.	1.0075e-46
NC_008536.1\|WP_011681889.1\|134398_134800_-\|BlaI/MecI/CopY-family-transcriptional-regulator	gnl\|CDD\|367747	pfam03965, Penicillinase_R, Penicillinase repressor. The penicillinase repressor negatively regulates expression of the penicillinase gene. The N-terminal region of this protein is involved in operator recognition, while the C-terminal is responsible for dimerization of the protein.	1.13996e-34
NC_008536.1\|WP_011681873.1\|114048_115002_-\|metallophosphoesterase	gnl\|CDD\|277324	cd07378, MPP_ACP5, Homo sapiens acid phosphatase 5 and related proteins, metallophosphatase domain. Acid phosphatase 5 (ACP5) removes the mannose 6-phosphate recognition marker from lysosomal proteins. The exact site of dephosphorylation is not clear. Evidence suggests dephosphorylation may take place in a prelysosomal compartment as well as in the lysosome. ACP5 belongs to the metallophosphatase (MPP) superfamily. MPPs are functionally diverse, but all share a conserved domain with an active site consisting of two metal ions (usually manganese, iron, or zinc) coordinated with octahedral geometry by a cage of histidine, aspartate, and asparagine residues. The MPP superfamily includes: Mre11/SbcD-like exonucleases, Dbr1-like RNA lariat debranching enzymes, YfcE-like phosphodiesterases, purple acid phosphatases (PAPs), YbbF-like UDP-2,3-diacylglucosamine hydrolases, and acid sphingomyelinases (ASMases). The conserved domain is a double beta-sheet sandwich with a di-metal active site made up of residues located at the C-terminal side of the sheets. This domain is thought to allow for productive metal coordination.	1.15666e-31
NC_008536.1\|WP_011681872.1\|111969_114162_+\|amidohydrolase-family-protein	gnl\|CDD\|238624	cd01299, Met_dep_hydrolase_A, Metallo-dependent hydrolases, subgroup A is part of the superfamily of metallo-dependent hydrolases, a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the members have a conserved metal binding site, involving four histidines and one aspartic acid residue. In the common reaction mechanism, the metal ion (or ions) deprotonate a water molecule for a nucleophilic attack on the substrate. The function of this subgroup is unknown.	3.31867e-64

>NC_008536.1|WP_011681880.1|121688_122501_-|electron-transfer-flavoprotein-subunit-beta
MSASFQIVVCGSFVPDPLQTLEPVGSPAGPSLKNELILPAVLDPWAGHALFEAAHLAQKMPGSKVWLVSLGAKAKLQQVMMSVAQKAPFELVALDGPASGFGDSCETAAALAGAVEVIAGLDRSRLLLFGGWESASRGAGSTLQMVGERLGITEQFQGVDQISVREDGSFEILERVEGGRHQVSVCAAPPAVLGWATGHLPEPKNNPQVGMANMRTVMPALQRAKPAPIANSGLCFASVTLPKQQRETRVVKNMPAEEIAREIVAWIGEE
>NC_008536.1|WP_011681879.1|120685_121687_-|electron-transfer-flavoprotein-subunit-alpha
MQNILLLAHTETDGSLGKPALEALTTALALGGTLTVGLVGATTQSAADQVAGAGAARFLAVTGEAFGQPRYSTDAAAAEALCRAAECTLVIAAGTSRWARALPGVAHRLGGRVDTHATALDERNGVPAVTRWFYRQRMEAVLTRAQRPWIVLLDTGCVAPWSGAEGTAVVEAVAADAATRTTVSGYRAPQTDEQTIRPDAKLLFVAGAGWTKKQGDGSVHSPEAEQLILGFLRKTQASLGGSKSLVDLSGEGEAVLRFMTHMNQIGQTGSTPRHPKGLSTCCHGEEPHAVGWRFVEQRRAINLDANCGWARGKADVLYVADAFEVMRRVNELL
>NC_008536.1|WP_063720780.1|119652_120537_-|alpha/beta-hydrolase
MRAAWENAEVDRKPELKMVRTADQELAVWEWAGAGPAILFAHATGFHGRCWDRIIQMFPERHCLAVDARGHGRSSKPEPPCHWRDFGRDLVAVAAHWDLRGATGVGHSMGGHITTQVAALRPETYRALLLVDPTIFPLEYYGTEPPDAHFTLRRRNVWNSPDEMFERFKNRMPFANWRPEILHDYCEYGLLPNNGDFVLACPPAVEASIYLNSKEPGSNIYPEVAMVGHPVVVMRAGKTRNPEIFDLSASPTAPDLASHFACGREIVLPDASHFIAMEAPERVAEEIRALEFSL
>NC_008536.1|WP_011681877.1|117790_119605_-|ABC-transporter-ATP-binding-protein
MSRRRAPLRRLSIRELLRPHRKSLALGLIAVVVEGIAGLLEPWPLKIVLDNVVKQKALSGWLNHLVLSVAGNDRLAILKFAAMLALGIAVVGSLAAYTEKYLTTSVGQWVMHDLRRSVYFHIQRLSLDFHDRRQTGDLISRVTSDIDAIQSFIASGLLSSLVNGLTLFGMVGVMFYINWRFTLIALSVAPVLFVVVYSYTRRIKKASREVRKKEGEIVSVIQEVLTSIRVVKAFAREEYEQRRLEEESLESVEAALHARALKARLSPLVDVIVAIGTSLVLWFGARLALQGSLSAGSLVVFIFYLGKMYKPMQELSKMTDSYSKAAVGYERIKEVMDTESDVKDLPGARPAPPLQGAVQFEHVSFRYPDSGPILRDVSFRIEPGQVAALVGPTGAGKTTIASLIPRFYDPTDGVVRVDGLDVRSLQQKTLRRQISFVLQETLLFHGTVWANIAYGKPDATRTEIIRASQIANANEFVEKLPQGYDTMVGERGVTLSGGQRQRIAIARAVVRDTPILILDEASSGLDAASEKLVFEALDRLMEGKTSLVIAHRLSTIRRADIILVIKDGEIVERGTHDELLSVGGLYAELHALQFGGEEAAARQI
>NC_008536.1|WP_011681876.1|116687_117692_+|hypothetical-protein
MIVRKGAIGIAALALGALMPLAGSKPAGSKPGKATVAKGTPVLWRDPGNDLNLYYGPGSRAREPRAPFTFIKEDTGGSSPKYTVSDARGAKWKIKLGLESRAETAASRLVWAAGFFANEDYLVPELRVENLPAHLKRHKLIEPGGVMRNARLKRESHDEEKIGEWKWRDNPFRDSREWYGLRAVMALLNNWDVKDENNAIYRRGDELIYMVSDVGATFGAAGRSWPASRSKDNLKIYSASRIICAEHDEFIDFCAPGRASIAHLVDPLEFHRRLKLRWVGRDIPRAHAKWIGVILARLSSDQIRDAFRAAGYSPAEIEGFTDAVQQRIATLTDL
>NC_008536.1|WP_011681875.1|115512_116607_-|phosphatidylserine/phosphatidylglycerophosphate/-cardiolipin-synthase-like-protein
MKVFIQPGDGVAPLVKAIDSAKTSVEIVIFRFDQREAERAMANAVQRGVAVHALIAHTNRAGEANLRKLETRLLGYGVTVARTADDLVRYHGKMMIIDRREVYLLAFNMTYLDIERSRSFGVVTRNREVVREAGKLFDADVKRHRYEPGSPTFLVSPANARKELAAFLKAAERQLLIYDPEVSDPGMVNILSDRAKAGVEIRIIGKMPRKGVALTVRKLDFRLHTRTIIRDGKSVFLGSQSLRELELDARREVGIIFREPKAVAEILRVFEEDWSARALAPAMEGPEAPPVRKLAKKVAKAVVEELPPVAPVVDQMAKELGVQGNVAVDVGRVEEMVKHAVKEAVRDAVTEVVAGETNDESNVA
>NC_008536.1|WP_157675047.1|114998_115535_-|hypothetical-protein
MTNRMWRNAAAILTCAALAHGANALDEFQRRIADYVKVHEQAQSSTGKLKPTTSAARIADHEQELASRIREAREGVVEGNIFTARTGKVFRRLLAHATGGRDATTVHQSLRRSEPVVVPLRVNEAYPERVPLQTTPPSVLQYLPKLPPQLEYRVVGRALVLRDTGANLIVDFLPNALP
>NC_008536.1|WP_011681873.1|114048_115002_-|metallophosphoesterase
MKIPALFCILAIAGAGLPGQNANPELALPLKPKSVRFAIIGDFGTGGERQYELAPQINHYHEIFPFEFVLTMGDNLYGGQHESDFKWKFEYPYRVLLDSGVKFYASLGNHDSPNQVYYKPFNMNGRRYYDFRRGDAAFFALDSNYMDPEQVAWLRKELTASNAKWKICYFHHPLYSHAKMHGSDTDLRKTLEPLFEETGVRLVLSGHEHVYERLKPQHGIYYIVLGSSGELRPHDLRPSPDTAKGFDTDNTFAIFEISEDECYFQVISRMGLTVDSGAIPSLLIEKSGTPNPLALQHHEGNTLGGADLLQRVAVHHQ
>NC_008536.1|WP_011681872.1|111969_114162_+|amidohydrolase-family-protein
MKAYIALFKNNMRLTLRDRGVLFFNYLFPLIFFFAFAELFHAGVGGGIAYFVSTVLVMGILGNGLWGAGMRSVQEREANILRRFKVTPISPLPILVAAMVSGWLLFVPVLFLLVGLAHFLYAMPLPQNWFSLFLMASLGVCSLRAIGLILAAVTNTMQEATIAIQILYMPMLFLSGATFPAAMLPKWAQTLAQFMPASYLVTGFQGIFFQNQNLLDNKAAVGALLATILLGTFLAMQLFRWEKEERIQPRKKLWVIAVLAPFAVLGTWQMFSKEHLGENQALFRQLQRSDRFLIRNTRIFTGDGAVIENGSVFVHDGKIAEVYQGTAPDPEQIKAEVIEGAGKTLLPGLIDVHVHLAASGGLGGSDSEFQLAMQHSAAALLYSGVTAARSVGDGLDASLKLRKSLDSGARLGANLFICGPMFTAEGGHGTEFVEHLPPAIKNSVRAQLIRTPKTPEEARKQVRDLKAAQVDGIKAILEAGWGDGMLFDRLDLLIVRAVAEEAHAQRLPLAIHTGDARDVADAIEIGTTSVEHGSWRDEIPDRLLERMAHGGIYLDPTLGVIEAYANYFAGKSDALGNSLVQQVVSGQLLKNTREFLASGKAVNPDRAEQFQHALDQARANLLHAWKAGVPLAMGTDSGNPMVFHGPSLHHEIQLWVQAGIPIPVALQAATVNAAKLLGAGQRIGAIRKGMDADLLMVDGNPLQEIGATERISLVVLKGERIRRAALFDQK
>NC_008536.1|WP_011681871.1|111049_111973_+|ABC-transporter-ATP-binding-protein
MDNPIQVEALQKSYGTFPAVKGISFDVRAGEVFGLLGPNGAGKTTTVEILEGLRSRSGGRVSVLGCDPEVQTLQLKDRVGVCLQATNLQEKITVGEAVELFAAFYTRTVDGHHLLKRLQLWEKRDTHYAKLSGGQKQRLALALAMLNDPQVLFLDEPSSGLDPQARLEIHELVLDLRREQRTILLTTHYIEEAEKLCDRVAIVDEGRIVAIGTPREIQERALASCTIEIETAAALGDIVLPEWPDAQKITLNDRRTHIAVTTGKPARIVVDMVKWLDEKGVELADIRIRRPSLEDAFIELTGKSLRE
>NC_008536.1|WP_011681882.1|124014_125736_+|Omp28-related-outer-membrane-protein
MTARILTAVCFSLALTGAIAQTPSPAPPDADKPTARETPPDQKAYADVMKITDPGKKIEALEKFRKDFPDSMFASGVDSTILSTLIQKMPDQKPRIKKTAQAMYAAAVAKDKAASKNNIVVTTAARGIAANRIADQLLSGDMLLKGAESYAKKGVDSMQQSIWIAEQREAFANRKQPIPAQEELVKRFQQARAVRIATLGLVERKLGRTAQAQKLLLEAYAVNPASAPVAGALGEMAAKAGEDSKAMDYLISARLTGNATAAANEGFETLYKKTHNGNTDGLEAMLDSEYHKRFPNPVHVEAYKPTAARTDRVVLAEVFTGSGCPPCAGADIAFDAAMERYARKDLAVVMYHVHIPRPDPMTNPDTLARAKSYSVTGVPSFAIDGKKTVGGGSRDMAPGVFDRFRKDLEKDLDTAAEAKIKVDAGLTGGSVKVSAAVDGVESDSKELKVQILLVEKEIRHLGENGVRFHPMVVRAIGGEKAGGYTLEPRGKGTFEATFDLDAVSKALKAHLDDFESKREGFKFSAKRDQINRADLAVVVFVQDDKTKHVLQSAYIDLGTGPGSRPTTEANNLK
>NC_008536.1|WP_011681883.1|125732_126203_+|hypothetical-protein
MKKIAFAAILTAALMAAPSDPVAWKLQTASAAPVKPGARFNVKLLATVQNGWHLYSMKPMAEGPIATRIWIGDGQPFSLAGGVQAPDPQVVQDPTLGMEVELYEGEAQFTLPVKIAAGTAAGAHALVVSASYQSCNDKICLPPKTVKVEIPVTVAR
>NC_008536.1|WP_157675048.1|126236_126407_+|hypothetical-protein
MLRLVPTFADILSGFTHILLDFLRPALEFFGRAVRVPAYLARGRIGAPVVTAARRE
>NC_008536.1|WP_011681884.1|126484_127969_+|carboxylesterase-family-protein
MPNRQVRRILAAGAIGAMSLSAALNQPVKTKTGLVSGVPGRDVSITAFKGMPFAAPPVGNLRWRAPQPAADWPGVRKAAQFGSSCIQNIVTEHKPWTYEFMTHNEISEDCLYLNVWTGARAAGEGRPVYLYIYGGANTEGSSAVPVYDGEGLAKKGVVVVTVNYRLGILGFFAHPELSKEAEYHASGNYALLDLVAALHWIHENIAAFGGDPAKVTIGGQSAGGANVHSLMASPLAKGLFRAAIIESAGGGSRPLADQEQAGVKFAESKGARSLEDLRKMSWKDLTAPQPIRFSSAAVDGYVLPNPPVEIDVPVLTGTNKHESGATPHPDVTPAAYQEQVRRRYQDLADEVLALYPATTPNDLAWDTARVSNHRSATAKKKVYTYFWDHALPGPDADKYGAFHSSELPYVLSSLAAADRPFTAADQKIADTMSSYWANFIATGDPNGKGLPHWPSAAEKPGFTMEVGDTTAPIPVAGSDAKRKLLEKYFAGQDR
>NC_008536.1|WP_011681885.1|127986_129822_-|4Fe-4S-ferredoxin
MSEPTIDRQSMDVDLVCVGFGPATAGFLTELSKHLVNPDGTPAIESPSNPGLPLQVICYERAEDISFGVSGVVTRARGIRASLPDLDCRGIPMAATVKQEKVAYLLDPHDASRRSPAMNFGDGMIRALALAHDHALELPYIPPFLHKEGGLVMGLGQFLQHVGGELMSGGTVQIWPGVPVESALFDEERVTGVRLCDQGVDKDGNPEGAFMPGMDVHAALTVVGDGPVGVVGRQLDEIFGLPDGHHQREWAVGMKMVVDLPEDSTLEPGMVFHTFGYPEPEIFGFFYVHPDRVATVGIFVPSWFQSPVRTSYRYLQHYMLHPYLWRHLKGAKLRSWGAKSLQESGKRGEPFLAGDGYARIGECSGSTNVLTGSGVDEAWTTGTQLAEAVVGLLKAGKPLSKENLEATYVARRRASWVEKEGRVAEKARDGFHHGMIPGLMGMAIAGFTAGKHSIGGEPGLMPSPEEYYREKIPAEELKHIQDDCRSRGAGCHNALMDRAGWPPIPYDGQLLVSHQDALLMGGKVQAPAGYADHVRFIYPDFCERCVSKMCIEMCSGQAISAGETGVPVFDREKCVHCGACIWNCATVLDDDPARGNISFRAGAGGLHSTEN
>NC_008536.1|WP_011681886.1|129818_132029_-|acyl-CoA/acyl-ACP-dehydrogenase
MTLAAIDQPTEYLRALPGDDVRQILWRFADRYDLQMLVQGVRAVARGPVARLVAAGARNTHEWTAEKNALLQAFDESGITGVFMDPSQGGFIEGPKNLALALVAFELAWVDAGAATGSLAGCLALSPIHERGTPEQRDHYMALAAPPRPGEDRKPWRGAFCLTEPIPYVGVETGMLGGKVRVAEWAEGQEPTLKVEKRGRFITNMGFANFVTAAVESDDPRIKGTCMVILEEGDPGIFDRGTPTRKLVHQLSSTRDPIFSLTVPAGRIIGGYSVKDGVIIPRYSHGEVIEAVFRRTRVTVAIMTSAKLLSAIEPVIRYHRNRFRGGSIATPGSPRHELGLQLKQDVVHRLVDVWATGEASAALGFEAARVFDRLDPLEKAKDQIMAMNGVKPGTATMKAMRAIQKDAIEVVHGKRPDRQDDPLVQYAILDSVANVLCPACKLWNTGHGARMMREAVSLMGGYGITEDCPGFLGHKWMDSQLEATYEGPEAVQRRQLSVTMTDELFLAQFREWIREMRLIANDRPETGACSLATAMQLWLWSLNHLQKALDADGGKLYQGSRQGVTFPLADALCWLLSSRCQILDLLELEKKGPELPTVAEGLPGLLAFLTDLCHVHSAHAAGEVGRVCAELVHGYNRHPAWDTEGCAGCYQSDDLECMEALIPGIASLARGYTDVIEHSGAHESKAGPCVRFQGLEQFATLRMRMDGCLTGSQLAKDRAADALTKVMIPEALDYPA
>NC_008536.1|WP_011681887.1|132218_132584_+|hypothetical-protein
MKWILALMAVSALTASAADISGNWKATAEGPNGAMERTFVFKVEGNKVTGESNSSMMGKSTISDGKVEGDTVTFTLNGKFGDQEVKLNYKGKINGNEIKFSSEMAGGGGGGAPIEWTAKKQ
>NC_008536.1|WP_011681888.1|132585_134412_-|peptidase-M56,-BlaR1
METVSRTLLTFLLNALWQVPVAWAVAALACRLMPNGPARLRHAVWVAALGCAFLLPVLSVRTPARTTLALPAATTPPIATAFAPSAFATAAPAPAHAAAPSISFPHDWAMLLLGAYGLFLALRALLFLRGLYRAFEIRRDAAPGGLHALLARCETAFSTRGVRLLRSADVSGPVALHRAIVLPEGMFEEFREDVLATAVGHEMAHIARRDFAFKLVYELLYLPLCFHPAAMWIRRGIERSREMACDELVTRHLLEPAVYARSIIALAGAALPVPQPGYVLGVFDGDILEERIRSLIERRGGDLRRARVALAGALATFVICAVFAGGMAVSGFAQSAAQSEMQAAAEAFSRGDVASGVEHFHKAVTLEPDNLKARLFLASAYVRQALAQHQYMPVNEDKPLLVMAQAQYQEVLKRDPKNASATFGMIALNGPSKAGESRETVLKLIASDPGNSEAYYTLGTVDWQIAYDASHSALEALGASPATQQIPDAEMRAHLRTKLTTYIDEGLRALQVALAKQPDSSDTMAYINLLLRQKGLLADTAQETKAYVAEADGWVGKALDAKRIQASKPKVNKGAIDLSGEPPLIVPAPPPPPPGTAPKPRNPAEGGR
>NC_008536.1|WP_011681889.1|134398_134800_-|BlaI/MecI/CopY-family-transcriptional-regulator
MPRKKNSDPGLTPLELQIMNVLWETGPSNVQSVQLNLKGRELAYTTVQTMLNVLHRKGKVKRLLKDRTYIYRPVLSRQKAVSQAVGEMLDRFFGGSADGLVLNLVETRQLTPEKLARIQELIDRPKEENHGNS
>NC_008536.1|WP_011681890.1|135454_136426_+|hypothetical-protein
MTISGILAILFALPLPAVAQGLRIDTAESDAVLAILAGGNERPRLLASEGYTRLKKREASMGRTFSDADFQAFLDSPALPEKRDALAATLREWKRADIEAIGERVRAFLPAEAKLKATVYIVIKPQSNSFVFDLKADPAIFLYLDPAKTRAQFENTVAHELHHIGLASLPDRTDPALPSKLRAAVEWLGAFGEGLAMLAAAGSPEVHPHRDSPPEDRARWDRDSKNLAHDMRAVEGFLIAVAKGELDENQRREKGMSFFGTQGPWYTVGWRMAVTVEQAKGRAELLECMRDMRRLLFDYNDAAKAAGFPQWSEELINAFRKPL

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Crispr_ID: NC_008536_3

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_008536_3

1661079-1661179

Orphan

Consensus_repeat	Method
GCGGGTCCTTGTGGACCTGCCGGACCTGC	CRISPRCasFinder

1 spacers

The CRISPR arrays of NC_008536_3

>merge|NC_008536|3|1661079-1661179|CRISPRCasFinder
GCGGATCCCTGCGGCCCTGCGGGTCCTTGTGGACCTGCCGGACCTGCGGGTCCCTGGGCGCCCGCCGGACCCGCGGGTCCCTGTGGACCTGCCGGACCTGC

>NC_008536|3|3|1661079-1661179|CRISPRCasFinder
GCGGATCCCTGCGGCCCTGCGGGTCCTTG	TGGACCTGCCGGACCTGCGGGTCCCTGGGCGCCCGCCGGACCC
GCGGGTCCCTGTGGACCTGCCGGACCTGC

Protein	Signature genes	Signature genes Name	Protein_function
NC_008536.1\|WP_011683112.1\|1654541_1655006_+\|ATP-binding-protein	unknown	unknown	gnl\|CDD\|379279
NC_008536.1\|WP_011683120.1\|1662719_1665542_-\|PAS-domain-S-box-protein	unknown	unknown	gnl\|CDD\|237425
NC_008536.1\|WP_011683114.1\|1655313_1655964_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|377552
NC_008536.1\|WP_011683124.1\|1671796_1672615_-\|hypothetical-protein	unknown	unknown	unknown
NC_008536.1\|WP_157675826.1\|1670100_1670679_-\|YceI-family-protein	unknown	unknown	gnl\|CDD\|377274
NC_008536.1\|WP_011683123.1\|1670684_1671800_-\|FAD-binding-protein	unknown	unknown	gnl\|CDD\|223717
NC_008536.1\|WP_041859028.1\|1672620_1673976_-\|aspartate-aminotransferase-family-protein	unknown	unknown	gnl\|CDD\|99735
NC_008536.1\|WP_011683126.1\|1674233_1675250_-\|LacI-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|224525
NC_008536.1\|WP_011683121.1\|1666037_1669934_-\|TonB-dependent-receptor	unknown	unknown	gnl\|CDD\|379297
NC_008536.1\|WP_011683110.1\|1652240_1653281_-\|nucleoside-hydrolase	unknown	unknown	gnl\|CDD\|224868
NC_008536.1\|WP_011683108.1\|1651382_1651778_+\|carboxymuconolactone-decarboxylase-family-protein	unknown	unknown	gnl\|CDD\|367130
NC_008536.1\|WP_011683107.1\|1651049_1651289_+\|hypothetical-protein	unknown	unknown	unknown
NC_008536.1\|WP_011683118.1\|1661717_1662059_-\|hypothetical-protein	unknown	unknown	unknown
NC_008536.1\|WP_049873427.1\|1653371_1654385_+\|Gfo/Idh/MocA-family-oxidoreductase	unknown	unknown	gnl\|CDD\|223745
NC_008536.1\|WP_157675825.1\|1656498_1659093_+\|DNA-polymerase-I	unknown	unknown	gnl\|CDD\|235591
NC_008536.1\|WP_011683113.1\|1655002_1655320_+\|STAS-domain-containing-protein	unknown	unknown	gnl\|CDD\|132914
NC_008536.1\|WP_011683127.1\|1675285_1676419_-\|glycosyltransferase-family-4-protein	unknown	unknown	gnl\|CDD\|340831
NC_008536.1\|WP_011683119.1\|1662062_1662617_-\|hypothetical-protein	unknown	unknown	unknown
NC_008536.1\|WP_011683116.1\|1659135_1659963_+\|DUF4159-domain-containing-protein	unknown	unknown	gnl\|CDD\|379342
NC_008536.1\|WP_011683109.1\|1651767_1652235_-\|GNAT-family-N-acetyltransferase	unknown	unknown	gnl\|CDD\|366181

Protein	Function_ID	Function_description	E-value
NC_008536.1\|WP_011683112.1\|1654541_1655006_+\|ATP-binding-protein	gnl\|CDD\|379279	pfam13581, HATPase_c_2, Histidine kinase-like ATPase domain.	1.65018e-25
NC_008536.1\|WP_011683120.1\|1662719_1665542_-\|PAS-domain-S-box-protein	gnl\|CDD\|237425	PRK13557, PRK13557, histidine kinase; Provisional.	2.2995e-56
NC_008536.1\|WP_011683114.1\|1655313_1655964_+\|hypothetical-protein	gnl\|CDD\|377552	pfam05719, GPP34, Golgi phosphoprotein 3 (GPP34). This family consists of several eukaryotic GPP34 like proteins. GPP34 localizes to the Golgi complex and is conserved from yeast to humans. The cytosolic-ally exposed location of GPP34 predict a role for a novel coat protein in Golgi trafficking.	1.27633e-27
NC_008536.1\|WP_157675826.1\|1670100_1670679_-\|YceI-family-protein	gnl\|CDD\|377274	pfam04264, YceI, YceI-like domain. E. coli YceI is a base-induced periplasmic protein. The recent structure of a member of this family shows that it binds to poly-isoprenoid. The structure consists of an extended, eight-stranded, antiparallel beta-barrel that resembles the lipocalin fold.	3.67053e-29
NC_008536.1\|WP_011683123.1\|1670684_1671800_-\|FAD-binding-protein	gnl\|CDD\|223717	COG0644, FixC, Dehydrogenases (flavoproteins) [Energy production and conversion].	6.60326e-34
NC_008536.1\|WP_041859028.1\|1672620_1673976_-\|aspartate-aminotransferase-family-protein	gnl\|CDD\|99735	cd00610, OAT_like, Acetyl ornithine aminotransferase family. This family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The major groups in this CD correspond to ornithine aminotransferase, acetylornithine aminotransferase, alanine-glyoxylate aminotransferase, dialkylglycine decarboxylase, 4-aminobutyrate aminotransferase, beta-alanine-pyruvate aminotransferase, adenosylmethionine-8-amino-7-oxononanoate aminotransferase, and glutamate-1-semialdehyde 2,1-aminomutase. All the enzymes belonging to this family act on basic amino acids and their derivatives are involved in transamination or decarboxylation.	3.65072e-125
NC_008536.1\|WP_011683126.1\|1674233_1675250_-\|LacI-family-transcriptional-regulator	gnl\|CDD\|224525	COG1609, PurR, Transcriptional regulators [Transcription].	1.32619e-106
NC_008536.1\|WP_011683110.1\|1652240_1653281_-\|nucleoside-hydrolase	gnl\|CDD\|224868	COG1957, URH1, Inosine-uridine nucleoside N-ribohydrolase [Nucleotide transport and metabolism].	1.35048e-68
NC_008536.1\|WP_011683108.1\|1651382_1651778_+\|carboxymuconolactone-decarboxylase-family-protein	gnl\|CDD\|367130	pfam02627, CMD, Carboxymuconolactone decarboxylase family. Carboxymuconolactone decarboxylase (CMD) EC:4.1.1.44 is involved in protocatechuate catabolism. In some bacteria a gene fusion event leads to expression of CMD with a hydrolase involved in the same pathway. In these bifunctional proteins CMD represents the C-terminal domain, pfam00561 represents the N-terminal domain.	9.01431e-16
NC_008536.1\|WP_011683121.1\|1666037_1669934_-\|TonB-dependent-receptor	gnl\|CDD\|379297	pfam13620, CarboxypepD_reg, Carboxypeptidase regulatory-like domain.	3.04941e-18
NC_008536.1\|WP_049873427.1\|1653371_1654385_+\|Gfo/Idh/MocA-family-oxidoreductase	gnl\|CDD\|223745	COG0673, MviM, Predicted dehydrogenases and related proteins [General function prediction only].	8.79969e-71
NC_008536.1\|WP_157675825.1\|1656498_1659093_+\|DNA-polymerase-I	gnl\|CDD\|235591	PRK05755, PRK05755, DNA polymerase I; Provisional.	0
NC_008536.1\|WP_011683113.1\|1655002_1655320_+\|STAS-domain-containing-protein	gnl\|CDD\|132914	cd07043, STAS_anti-anti-sigma_factors, Sulphate Transporter and Anti-Sigma factor antagonist) domain of anti-anti-sigma factors, key regulators of anti-sigma factors by phosphorylation. Anti-anti-sigma factors play an important role in the regulation of several sigma factors and their corresponding anti-sigma factors. Upon dephosphorylation they bind the anti-sigma factor and induce the release of the sigma factor from the anti-sigma factor. In a feedback mechanism the anti-anti-sigma factor can be inactivated via phosphorylation by the anti-sigma factor. Well studied examples from Bacillus subtilis are SpoIIAA (regulating sigmaF and sigmaC which play an important role in sporulation) and RsbV (regulating sigmaB involved in the general stress response). The STAS domain is also found in the C- terminal region of sulphate transporters and stressosomes.	1.21252e-25
NC_008536.1\|WP_011683127.1\|1675285_1676419_-\|glycosyltransferase-family-4-protein	gnl\|CDD\|340831	cd03801, GT4_PimA-like, phosphatidyl-myo-inositol mannosyltransferase. This family is most closely related to the GT4 family of glycosyltransferases and named after PimA in Propionibacterium freudenreichii, which is involved in the biosynthesis of phosphatidyl-myo-inositol mannosides (PIM) which are early precursors in the biosynthesis of lipomannans (LM) and lipoarabinomannans (LAM), and catalyzes the addition of a mannosyl residue from GDP-D-mannose (GDP-Man) to the position 2 of the carrier lipid phosphatidyl-myo-inositol (PI) to generate a phosphatidyl-myo-inositol bearing an alpha-1,2-linked mannose residue (PIM1). Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate residue. This group of glycosyltransferases is most closely related to the previously defined glycosyltransferase family 1 (GT1). The members of this family may transfer UDP, ADP, GDP, or CMP linked sugars. The diverse enzymatic activities among members of this family reflect a wide range of biological functions. The protein structure available for this family has the GTB topology, one of the two protein topologies observed for nucleotide-sugar-dependent glycosyltransferases. GTB proteins have distinct N- and C- terminal domains each containing a typical Rossmann fold. The two domains have high structural homology despite minimal sequence homology. The large cleft that separates the two domains includes the catalytic center and permits a high degree of flexibility. The members of this family are found mainly in certain bacteria and archaea.	9.98722e-68
NC_008536.1\|WP_011683116.1\|1659135_1659963_+\|DUF4159-domain-containing-protein	gnl\|CDD\|379342	pfam13709, DUF4159, Domain of unknown function (DUF4159). Members of this family are hypothetical proteins.	3.36748e-45
NC_008536.1\|WP_011683109.1\|1651767_1652235_-\|GNAT-family-N-acetyltransferase	gnl\|CDD\|366181	pfam00583, Acetyltransf_1, Acetyltransferase (GNAT) family. This family contains proteins with N-acetyltransferase functions such as Elp3-related proteins.	1.57651e-14

>NC_008536.1|WP_011683116.1|1659135_1659963_+|DUF4159-domain-containing-protein
MRVAIAVVLFSVWLAAQTVWREYPAFEYNDFPIPADYQEKTEWAFARLMYPNAAFGGGFGRRGRFGGGDWREGGRGIFWTMDYPRSDRHFSVALRRLTRIHARSVEQPVNLDEGYQYNWPWLYGVEVGHWNLSDQQAALLREFLLRGGFFMCDDFHGTDEWSVFVSSMRRVFPDREIVDLEDAEPIFHSIYDLDGRYQVPGASPWFGAGITYEHGGTVPRWRGIYDDHGRLMVAICHDMDLGDSWEHADNPDYPEKFSALGIRIGVNYVVYAMTH
>NC_008536.1|WP_157675825.1|1656498_1659093_+|DNA-polymerase-I
MGAVARQKLFLIDTFGFIFRAYHARARTGAPPMRTSTGFSTEAVYIFNNMLRKLSKQHDPPYVAAIFESGEATHRVQEFAEYKANRTETPPDLLDQIPFVRRVLEAMRIPILEYPGFEADDVIGTITRRAEAEGLDVVIVSSDKDMLQLVTEHVSMLNPAKDDKLYNPEEVKTFMGVPPVQVADLLALMGDSVDNIPGAPGIGDKGAKQILEKFGSIEAALERAAEVERKVYRESLQNNVDRIRMSKRLATISTDVPIEFTLDAVKAQAPDPGLLKAIYKEMEFHSLLKELGPSEDTRERRYSVIGSAGELREWLAGAAGTPVAVAITKSTEGEFALDMIAADTIGLARKRGEACAVTSELIVELKPWLEDAAVVKVACDVKSAVLQLARLGIEARGFGHDVMIYGFLLDADPGGCGLENQAHRRLDLKLGGAAEQHADITLELYEQLAPAIDGRGLRKLYDEIELPLTRVLARMERTGIRIDGAELKRLSVLMESQISGLTAEIHALAGKPFNISSPQQLGKVLFEDLNLPAPVKYGKGKTISTAADVLDELAAEHEIVRKVLEYRQLTKLKGTYVDALPALIDPATGRLHTSFNQTGAATGRLSSSNPNLQNIPIRTSLGREIRAAFVPRDGWKLLVADYSQIELRLLAHMSGDELLVQAFREGEDIHTRTAAEVMGVPPLMVTPEARRDAKAVNFGIVYGISAFGLAAQLGIGRAEAERYIKNYFARYVGVKRFIEETIAEVRKTGVTKTLFGRERPIPEINGRNPNARGFAERTAVNSPLQGTAADLIKLAMVRIDAALAAGGFQAAMLLQVHDELVFECPPEELDEVSRMVKREMEGACELKVPLVVDVGSGDNWRDAK
>NC_008536.1|WP_011683114.1|1655313_1655964_+|hypothetical-protein
MLSMLEEVVLLAVDEKNGGLRSTREFGTAYALVGAVFFDLALARKIDTDTETIQIIDTTPTGNATLDRVLTHMASRPDLTTVRGWLEEIFQQRDDMEGEALQSLIEQGILRHEKSKLLWIIDVERFPLVDNKPQQYVKVRLANTILADDIPQTRDIMLVSIAEPCGLLSYVLSDTVLASRRQRIHLLCNLETISRKVADSILGLETSMRQAMTKVV
>NC_008536.1|WP_011683113.1|1655002_1655320_+|STAS-domain-containing-protein
MIQLTEETKGEWCIVGVRGRLDAESADELEGALRGAIGKHAKVAANFAAVDYISSAGLRAVIQAARAAEGKEVEFTICSMTPHVKKVFDMSGLHQILHLRGELPC
>NC_008536.1|WP_011683112.1|1654541_1655006_+|ATP-binding-protein
MNGEGVVWHNQAIPYKADFSLNGNLSELERLSAEISRFCRENSLDEEAEFQLNLVLEELFVNTMRHGGCEGAQNSTRVRLRSEADGVEVVFADRGVPFDPTSVPAANVAAPLEERRAGGLGIHLVREIMRDLQYRRAGEWNQISMKRPHGPREL
>NC_008536.1|WP_049873427.1|1653371_1654385_+|Gfo/Idh/MocA-family-oxidoreductase
MKKVRWGVLGVARIAVNRVIPAMQAGEWSEITAIASRDRGRAASAASELKIPKAYGSYEELIADPEIDAIYNPLPNHLHVPWSVRAAEAGKHVLCEKPVGLNVAEALRLVEVRDRTGVTMGEAFMVQSHPQWVRIQELVRGGRIGELRSAIGSFSYFKLEAENIRNIREYGGGGLMDIGCYPIKTSRMVFGDEPVRVSAAVKRDPQFGNIDMLTSAILEFPSGHCVFTCSTQIMQQQSMCFYGTTGRIQPEIPFNATPGGTSRIFIDDGRDLTGGGRVVEEFPACDQYTIQGDLFSRAIREGGTPPVPLEDAVRNMAVIDAVFRAGETGKWETVKVD
>NC_008536.1|WP_011683110.1|1652240_1653281_-|nucleoside-hydrolase
MSRFLAMFLVVTCLAATTRDLVIFDTDSGLFGDDGAALVMLLRGSSQEVLQGITIVPGNVWAAQGAEYMFHILDLLKKPQMQVAVGAEAPLIHTAAMSKEFDRRWGGLGYTGAFAQDPTAVVPAPGSKISTRKLRRDAINFLISEIERHPGEITILALGPMTNIALALRLKPDIETKIKRIVFMGGNIRVAGNATPAAEFNFWFDPEAARIVLRSRIPKKMMFGLDICNLAKIRKAEFDQIASARNPIAELFREDLGNRYPGFLKKPDAIGFMWDSLAAAYLLDPDFVTKTESRYLDVQTTWGQFYGSTTPLDRRATPTATPVTVMLDLDFKRVFALYKDRLVRSE
>NC_008536.1|WP_011683109.1|1651767_1652235_-|GNAT-family-N-acetyltransferase
MPVVAVSHPAQIEQVRILFQEYWDSFDFTPCFQNFSAELAALPGDYAPPRGALALALVDGQPAGCAALRPIDSLRCEAKRLYVRPEFRAHGLGKALLHWVIAEARARGYRELVGDTMPQMSRALEMYDRMGFERIQPYTANPTPGAIYLRLPLTP
>NC_008536.1|WP_011683108.1|1651382_1651778_+|carboxymuconolactone-decarboxylase-family-protein
MATFGFIEYADAAPEVRAVYDDIMATRQTDWINNFWKALAHDPATLRRTWESIKQIMAPGALDPLLKEMIYVAVSATNQCGYCIASHTASARKAGMTAEMFAELMAVVGMANETNRLASGYQVEIDERFKV
>NC_008536.1|WP_011683107.1|1651049_1651289_+|hypothetical-protein
MSKRQEARKADPLRGDQGSDFDAVPALGNPATTEAVKIHQIAAARYGDPETIRRGRQQQGVHPSPASKNQQGMHSVSAP
>NC_008536.1|WP_011683118.1|1661717_1662059_-|hypothetical-protein
MTTEQLTTADLANAAANGREPEQHLTPLLPNDFSEEMRTRWETIQTAFVDDPRVSVQQADELVASAIKRLAETFARERSQLEQQWSTGNDVSTEDLRQALRRYRAFFQRILSV
>NC_008536.1|WP_011683119.1|1662062_1662617_-|hypothetical-protein
MSTTVAIILIAVVLLAAVAVWAFLQRRTATLRRRFGPEYDRTVGEYGNRMRAEQALERRAERTEKYHIRPLAREEQQRFNEEWRRAQARFVDDPALAIRDADHLVSEVMRERGYPMADFDRRAEDLSVDHPLVIRNYRAAHDIAIAEQQGRANTEDLRRGMVHYRELFDELLEIQPANMPERRR
>NC_008536.1|WP_011683120.1|1662719_1665542_-|PAS-domain-S-box-protein
MKSSTFRRIAAITVSAGLFAALVYWYLAIRTPPIPRRALTIGFENVPPVQIRTAAGPAGLAVETVNEAARRAGITLRWVETGVSSEESFRRGLVDLWPIMADLPDRRKRLHITPPYIYTNHNLLLRPGSARPERDFNGTIAYFKLPLHLRLVHAAFPQAHLVPVADFRHVIQAVCKGTVDLGFLEDRAALAELRDRPPECESIALRVEPLPEMRLPLGVASTFECARAADRLRGEIGKMFSDGTLAATMAKYSYYGLDDTWSTYALMEASERARWVAWIAGLLGLVLAVILWQAASLRQRKRSESALRASEERFRAIFNQAAVGDAQVTLDGQVTMVNDRYCEVLGYGREELLGQPLAGKIHPDDRETLLLNRRRLLDQVVPSYSVEVRSVLQGGETVWIKLYESLLRDAENRPQYSLAVVEDITERRQAETALQESERRFRSMADTAPVMIWVAGADQRCTFFSQGWLRFTGSSMEDALGNGWVEHIHPESRELCQANFNSAFATQSSFQTECRLRRADGEYRWVLATGTPRFGADGAFAGYVGSCTDITDIKNAQVEALARQKLEGLGVLAGGIAHDFNNLLGSILATSELVLSELPDGTPASEGIISIKNVADRAAEIVRQMMAYSGQENTIFEALDLSVLVREMLQLLSVSISKRAHLVVDLPENLPAIRANPAQLRQVVMNLITNASEALGESSGVITVGLAHVRPAAPRPAGHPAEITETGHVRLTVADSGSGMTEEIRARIFDPFFTTKFAGRGLGLAAVRGIIRDHGGSISVFSVPGQGSRFEVVLPCTDRPTPSNNGSCPADSSARFEQLFGTILVVEDEEDLRLAVAKMLRKRGFSVMEAADGCIGVELFQAHSADIDVVLLDLTLPGKTGREVLEEVRRMRHDVSVILTTAYSYEAALRTAGGHESWQYLRKPYRIAEVLDMLRAATSR
>NC_008536.1|WP_011683121.1|1666037_1669934_-|TonB-dependent-receptor
MKTLGLTWLLLAGFALSAFSQVTTGRIEGAITDPQGSAVPGAQVKVTNNLTGQILDSVSDEKGLWSMPSLSTSTYTIAVSHPGFKSITIENVKVDAGVPATVNAKLEVGSVSETVEVMGGAEVLQTQTATVTSTLVGRQLHDLPFTSRNLTELIVTQPGSATPGVPRSTSVYGLPQSAMNVTLDGINIQDNSNKSSDGFFNAIFPRADAIEEMTVSSAAAGADSNAEGAMQVKMVTRSGSNSYHGGLFEQHRNQDLNANAYFNNLNGTAPRDHLVFNQFGGLIGGPIKRNKLFFFGHFEAFQLPQTYTEPTGTVLTPEALAGNFRYRDSGGVVRSVNLLQLAGANGFTSTVDPSIGKSLAQIASLTGDAPGLKSRIATNADYNRNNLDFQSKGGNYRRFPTTRLDYNVTEKHHIEFVYNYQTNIRRPDGVNIGTASPIFPGTGNVLGGTEFGNQGGIAFSAVAALRSTLTSKLVSEVRFGIVGGTVIFNNGINPGDFAQWSGYAPIFSSTNCNAGTAYVTCPYRTTGQTRRNTPLKQGNANLTYSMNAHLLNFGGSFTQVNAWTTSVNGTQIIPTVNFGVATGDPIITGATNIFTAANFPGANATDLQTNAPALYAMLTGRVSAVNRSVILDDQTKTYGAFPPVVKNQQREFGLYFQDSWRLHPRLTFNYGVRWDRQNPPVNLNGVYTRPGYAGVWGVSGVGNLFKPGTLTGQVPVFNATAAGEAGYATHNKQFSPSVGLAWQVPSATGPLGWIFGKGSVIRAGYAINTIREDASTLALWGGNQGRTITLNVDPTNFPAQFGAPGSVLFRNPLPSRVAPTTPSFPLAVAAGNSVSDFSPNLKTGYVQSWDIGIQRELTRDTVIEIRYVGNHGTDLWRQINLNEINTIENGFTNEFKLAQQNLALARGCSASDPVCMSVNRSKSNQYFGLPGQAPLPMIFTALAANNDATSALQIEQGQAGALANAIATNTTRMARLTAAGLPVNLFQVNPTLVSGAANLEVNGGNTNYNGLQVEVRRRMSKGLLFQGSYVWSHSISNEQSQGIAGSFVTMHDVGYDKGPSPYDIRQAVKMNWVYELPFGPGKRYFGHSGSPIVRKALEGWQLASVTRLQSGSPIRLTSGRLTMNQNDSGVILHNLTVSQLQSMMQIRKVTLAATANSGPIGAVFYLPQALLDNTNAAFEVNGKTLANLDKNAPYIGPADQPGQMGERVFLYGPMQQKWDFSLGKKTNIGEHANIEFRMQALNAFNLTNFLLFVPGSGITTTLGANGTGFGQTSGAYRDLSNTNDPGGRIIEFSLRLNF
>NC_008536.1|WP_157675826.1|1670100_1670679_-|YceI-family-protein
MLRLCLPFCAAAVLLVAGDSIPAHPATSFVIDPAQTKVEFTLADTLHTVHGTFQLASGTLRFDPATGAASGEVVVDARSGDSGSKARDKRMHANILESAKYPQIAFRPDRLEGKLAPEGKSQVQLHGMFSIHGAEHEITVPAVVESTGGQYNVAATFAVPYVKWGMKNPSNLILRVGDTVEISLHTVAAASK
>NC_008536.1|WP_011683123.1|1670684_1671800_-|FAD-binding-protein
MNPLPRATDLFVIGGGPAGLAAAIAARRRGLDVTLADCSLPPVDKACGEGIMPDGLAAARALGLDLSGTGGHCFEGIRFVHGESSVEARFPNGHGLGLRRTDLHNLMVDHAIQAGVKLSWGTRISGISPQGVIARDRLVRARWIAGADGGHSPVRRWAGLDACHRESHRFGFRRHYRVAPWSDFMEVHWGESCQLYITPVSAGEVCVVLITSDQRQRLDDALPHFPQVAHRFAPGSATNLQRGGVTASRRLKSVCRGNVALVGDASGSVDAITGEGLCLLFQQSVALAAALEKDDLTAYQAEHRRIGRRPEFMGDMMLLLDHRRRLRSRALSALSREPGLFAKLLAMHTGPFSAANLITSGLSLGWRMLTL
>NC_008536.1|WP_011683124.1|1671796_1672615_-|hypothetical-protein
MNIRNLVPFALLGVLPAVAAPTVDLLDRGYREMYNMQFNEAHRTFEEYQRLHPDDALGPVSDAAAYLFGEFDRLHILQSEFFTHDQHFMTDHKLAPDPEVRRKFDAALAASRALAGRKPGDENAAFASILVNGLHSDYLALIDKRYGASFQEMKAGREMAENLLSRNPNYCDAWIAVGVENYMLSVKPAPMRFLLRLGGGQTDRKTGLEKLRVTAAKGRYLAPFARLLLAVAAMRDNNSPEAHSLLSALAAEFPSNPLYAQELARLDSGGTR
>NC_008536.1|WP_041859028.1|1672620_1673976_-|aspartate-aminotransferase-family-protein
MATTVPSLDRLYSDHVNPQWVRLLDLLQMNVQYERCSGSELFTTEGRRILDFLSGYCVHNAGHNHPAIVAALKDELDRSGPAMLQSHVPQLAAELAQRLLQRAGGNLQRVYFTNSGSEGVETAIKFARAHTGRTGLLYAAGGFHGLTCGALSLMSDPFWSDGFGPMLPGTQSVHFGDIAALESHLATRKFAAYILEPVQSEGGIQVPDASYLHAAQELCRRYGTLLVLDEVQTGMYRTGSFLAAHRFQVEPDMVILAKALSGGLIPVGAVLMTEAVSNSVFSSLKRAFVHASTFGENALAMRAGLATLDVLEHDDLGERSAATGARLRLHLAEALAPYEMVGAIRGLGMLNGIQFTAPRQLRLRVAFEGFQRIHPAMFGQVVVMRLFRDKGILTQICGNNFMVLKVAPPLVATDVQLEEFVDCVRDVVHLIHNSGAFWTDALGLARRAVGI
>NC_008536.1|WP_011683126.1|1674233_1675250_-|LacI-family-transcriptional-regulator
MSNASATPVRLKDIARDLNVSVMTVSKVVRGCADVGAETRGRVLARIKELNYQPNWVARSLAARRTFMIGLIVPDLMHSFFAEIAKGVAATIRPLGYDVVICNSEENGDLESSEVDRLLGRQVDGLLLASAQPPSSLAVFERIEARGTPYVLIDRRFADVHAPYVGADDEAIGRMATQHLIDRGCRRIAHIAGPAVTTGLGRQKGYEEALAASGINIPEGFIVQATDDDTGYQATRRLLKLTPRPDAIFGYNDPTAAGAMKAILEAGIRIPEEIKVIGVGNVHYSDLLRVPLSTIDQSSASIGQQAADILLKAIGNKRKRPAKTILIDPILIARESTR
>NC_008536.1|WP_011683127.1|1675285_1676419_-|glycosyltransferase-family-4-protein
MPGSKTIVSVYGFEPFRIGGGETFIRELSLLLGRRGWKNVVCFLTEPTPQVREFLSLPNVTIEVIPDVWQLKWQPTRDLARILRRYRPEILHLQFTGFVSPYPWLARFYGAKRVLFTDQASKPEGFVPRRASLFKRVATRIINWPLDRVTCISDYVLRCWTTLDVLQSERFTRIYNHVDFTRCQPDGSAFRKTLTIPDSRQIIVQVSWMIPDKGFDDLLAAARLVIARNPEAYFVMVGEGADRQRYIRETKELGLQDHITWTGILPDPLKMGVFSAADVVCQVSRWEEGFGYVIAEAMASGKPLVGTRVGAIPELVHHGKTGFLVDRRDPPAIAERILELLADRDLRCRMGQAGREFAFRNFDANVNIAEFLKLYGI

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Crispr_ID: NC_008536_4

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_008536_4

2821021-2821110

Orphan

Consensus_repeat	Method
GCCAGGATTGGCTGCCCCACAGAG	CRISPRCasFinder

1 spacers

The CRISPR arrays of NC_008536_4

>merge|NC_008536|4|2821021-2821110|CRISPRCasFinder
GCCAGGATTGGCTGCCCCACAGAGGGATTTTCATCCCCTTAAATGGCGCACAGCGCCATCGCGACAGCCAGGATTGGCTGCCCCACAAGT

>NC_008536|4|4|2821021-2821110|CRISPRCasFinder
GCCAGGATTGGCTGCCCCACAGAG	GGATTTTCATCCCCTTAAATGGCGCACAGCGCCATCGCGACA
GCCAGGATTGGCTGCCCCACAAGT

Protein	Signature genes	Signature genes Name	Protein_function
NC_008536.1\|WP_011683957.1\|2813359_2814127_-\|response-regulator-transcription-factor	unknown	unknown	gnl\|CDD\|225818
NC_008536.1\|WP_011683970.1\|2829144_2830641_+\|magnesium-chelatase	unknown	unknown	gnl\|CDD\|224160
NC_008536.1\|WP_011683962.1\|2821146_2821566_-\|YciI-family-protein	unknown	unknown	gnl\|CDD\|226318
NC_008536.1\|WP_157675861.1\|2818072_2819332_+\|IS110-family-transposase	unknown	unknown	gnl\|CDD\|376564
NC_008536.1\|WP_011683958.1\|2814110_2815244_-\|signal-transduction-histidine-kinase-LytS	unknown	unknown	gnl\|CDD\|225814
NC_008536.1\|WP_011683968.1\|2826509_2828255_+\|SpoIIE-family-protein-phosphatase	unknown	unknown	gnl\|CDD\|225118
NC_008536.1\|WP_011683964.1\|2822296_2824255_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|224720
NC_008536.1\|WP_095211921.1\|2815276_2815528_-\|hypothetical-protein	unknown	unknown	unknown
NC_008536.1\|WP_157675251.1\|2824979_2825603_+\|ribose-5-phosphate-isomerase-B	unknown	unknown	gnl\|CDD\|376799
NC_008536.1\|WP_011683955.1\|2811654_2812197_-\|sigma-70-family-RNA-polymerase-sigma-factor	unknown	unknown	gnl\|CDD\|237132
NC_008536.1\|WP_157675862.1\|2821629_2822151_-\|beta-glucosidase	unknown	unknown	gnl\|CDD\|214807
NC_008536.1\|WP_095211922.1\|2815526_2817623_+\|ankyrin-repeat-domain-containing-protein	unknown	unknown	gnl\|CDD\|222984
NC_008536.1\|WP_011683971.1\|2830648_2831881_+\|VWA-domain-containing-protein	unknown	unknown	gnl\|CDD\|227204
NC_008536.1\|WP_011683961.1\|2819510_2820740_+\|MFS-transporter	unknown	unknown	gnl\|CDD\|340863
NC_008536.1\|WP_011683954.1\|2810974_2811658_-\|DUF1109-domain-containing-protein	unknown	unknown	gnl\|CDD\|377671
NC_008536.1\|WP_157675863.1\|2825824_2826487_+\|deoxyribose-phosphate-aldolase	unknown	unknown	gnl\|CDD\|234784
NC_008536.1\|WP_011683969.1\|2828257_2829070_-\|signal-peptidase-I	unknown	unknown	gnl\|CDD\|274044
NC_008536.1\|WP_011683953.1\|2809986_2810970_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|369283
NC_008536.1\|WP_011683956.1\|2812193_2813261_-\|hypothetical-protein	unknown	unknown	unknown
NC_008536.1\|WP_011683965.1\|2824208_2824958_-\|high-affinity-nickel-transporter	unknown	unknown	gnl\|CDD\|236641

Protein	Function_ID	Function_description	E-value
NC_008536.1\|WP_011683957.1\|2813359_2814127_-\|response-regulator-transcription-factor	gnl\|CDD\|225818	COG3279, LytT, Response regulator of the LytR/AlgR family [Transcription / Signal transduction mechanisms].	4.49679e-50
NC_008536.1\|WP_011683970.1\|2829144_2830641_+\|magnesium-chelatase	gnl\|CDD\|224160	COG1239, ChlI, Mg-chelatase subunit ChlI [Coenzyme metabolism].	9.52029e-81
NC_008536.1\|WP_011683962.1\|2821146_2821566_-\|YciI-family-protein	gnl\|CDD\|226318	COG3795, COG3795, Uncharacterized protein conserved in bacteria [Function unknown].	2.50151e-48
NC_008536.1\|WP_157675861.1\|2818072_2819332_+\|IS110-family-transposase	gnl\|CDD\|376564	pfam01548, DEDD_Tnp_IS110, Transposase. Transposase proteins are necessary for efficient DNA transposition. This family includes an amino-terminal region of the pilin gene inverting protein (PIVML) and of members of the IS111A/IS1328/IS1533 family of transposases. The C-terminus is represented by family pfam02371.	6.46016e-24
NC_008536.1\|WP_011683958.1\|2814110_2815244_-\|signal-transduction-histidine-kinase-LytS	gnl\|CDD\|225814	COG3275, LytS, Putative regulator of cell autolysis [Signal transduction mechanisms].	1.08158e-54
NC_008536.1\|WP_011683968.1\|2826509_2828255_+\|SpoIIE-family-protein-phosphatase	gnl\|CDD\|225118	COG2208, RsbU, Serine phosphatase RsbU, regulator of sigma subunit [Signal transduction mechanisms / Transcription].	7.55953e-45
NC_008536.1\|WP_011683964.1\|2822296_2824255_+\|hypothetical-protein	gnl\|CDD\|224720	COG1807, ArnT, 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family [Cell envelope biogenesis, outer membrane].	0.00121723
NC_008536.1\|WP_157675863.1\|2825824_2826487_+\|deoxyribose-phosphate-aldolase	gnl\|CDD\|234784	PRK00507, PRK00507, deoxyribose-phosphate aldolase; Provisional.	2.7637e-114
NC_008536.1\|WP_011683955.1\|2811654_2812197_-\|sigma-70-family-RNA-polymerase-sigma-factor	gnl\|CDD\|237132	PRK12539, PRK12539, RNA polymerase sigma factor SigF.	7.97202e-33
NC_008536.1\|WP_011683954.1\|2810974_2811658_-\|DUF1109-domain-containing-protein	gnl\|CDD\|377671	pfam06532, DUF1109, Protein of unknown function (DUF1109). This family consists of several hypothetical bacterial proteins of unknown function.	6.95959e-12
NC_008536.1\|WP_095211922.1\|2815526_2817623_+\|ankyrin-repeat-domain-containing-protein	gnl\|CDD\|222984	PHA03100, PHA03100, ankyrin repeat protein; Provisional.	1.08834e-12
NC_008536.1\|WP_011683971.1\|2830648_2831881_+\|VWA-domain-containing-protein	gnl\|CDD\|227204	COG4867, COG4867, Uncharacterized protein with a von Willebrand factor type A (vWA) domain [General function prediction only].	4.17454e-102
NC_008536.1\|WP_011683961.1\|2819510_2820740_+\|MFS-transporter	gnl\|CDD\|340863	cd06173, MFS_MefA_like, Macrolide efflux protein A and similar proteins of the Major Facilitator Superfamily of transporters. This family is composed of Streptococcus pyogenes macrolide efflux protein A (MefA) and similar transporters, many of which remain uncharacterized. Some members may be multidrug resistance (MDR) transporters, which are drug/H+ antiporters (DHAs) that mediate the efflux of a variety of drugs and toxic compounds, conferring resistance to these compounds. MefA confers resistance to 14-membered macrolides including erythromycin and to 15-membered macrolides. It functions as an efflux pump to regulate intracellular macrolide levels. The MefA-like family belongs to the Major Facilitator Superfamily (MFS) of membrane transport proteins, which are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	1.70556e-52
NC_008536.1\|WP_157675862.1\|2821629_2822151_-\|beta-glucosidase	gnl\|CDD\|214807	smart00758, PA14, domain in bacterial beta-glucosidases other glycosidases, glycosyltransferases, proteases, amidases, yeast adhesins, and bacterial toxins.	7.64066e-16
NC_008536.1\|WP_011683969.1\|2828257_2829070_-\|signal-peptidase-I	gnl\|CDD\|274044	TIGR02227, Inactive_signal_peptidase_IA., signal peptidase I, bacterial type. This model represents signal peptidase I from most bacteria. Eukaryotic sequences are likely organellar. Several bacteria have multiple paralogs, but these represent isozymes of signal peptidase I. Virtually all known bacteria may be presumed to A related model finds a simlar protein in many archaea and a few bacteria, as well as a microsomal (endoplasmic reticulum) protein in eukaryotes. [Protein fate, Protein and peptide secretion and trafficking].	2.49635e-44
NC_008536.1\|WP_011683953.1\|2809986_2810970_+\|hypothetical-protein	gnl\|CDD\|369283	pfam07244, POTRA, Surface antigen variable number repeat. This family is found primarily in bacterial surface antigens, normally as variable number repeats at the N-terminus. The C-terminus of these proteins is normally represented by pfam01103. The alignment centers on a -GY- or -GF- motif. Some members of this family are found in the mitochondria. It is predicted to have a mixed alpha/beta secondary structure.	0.00239739
NC_008536.1\|WP_157675251.1\|2824979_2825603_+\|ribose-5-phosphate-isomerase-B	gnl\|CDD\|376799	pfam02502, LacAB_rpiB, Ribose/Galactose Isomerase. This family of proteins contains the sugar isomerase enzymes ribose 5-phosphate isomerase B (rpiB), galactose isomerase subunit A (LacA) and galactose isomerase subunit B (LacB).	1.79066e-68
NC_008536.1\|WP_011683965.1\|2824208_2824958_-\|high-affinity-nickel-transporter	gnl\|CDD\|236641	PRK10019, PRK10019, nickel/cobalt efflux transporter RcnA.	3.30103e-30

>NC_008536.1|WP_011683961.1|2819510_2820740_+|MFS-transporter
MASPTSTLGFRDVLQTPAVKRLWIAQISSIFGDFLAIFAIFSVVTFQLHGTPTQVSMIMVAFLTPFALISPIAGVFVDKWNLKATMIGSDLVRGLLVLTLVFVRDLYAIYAILFVMSVFSSFFVPAQSVAVRTLAPVGGLLAVNALMSQAVQSAQIITPSISGLMVDWLGANSCFLFDSLSFFVSAGLVYSLTIRRPTAGPAAAPSSLRASFAEGFQFIFTHSAISFVMIAMACGMFAVRCFGALLSVWVRDILHSDAKLYGLLNSLIGVGMITGTQTLRRFAARISPQRLVVYGLAGMGAAVLVTAAFNGLIATGLGMLGLGFFAACNMVTSQTLLQQETPQAMLGRVTSSLMSLLAVSQVLAMLFAGPVAQSAGIRNLYFVSAVMLIGIAGFGLTWLRRPQSTAAAA
>NC_008536.1|WP_157675861.1|2818072_2819332_+|IS110-family-transposase
MQTADGKRSRGELIHTPEAIDAWAAELAQRFGGRPVAITLEQARGALIATLSKYGHLHLFIVDPSRLNYYRKSVSPSGAKSDLVDGDLILDFQLKHPELVRYLAPDTVETRSLQFLTEQRRAVVNQHTRQVQILTHWLKQVFPQILAWFDDVSTPLVGDLLKRWPDLVKLKKARPETLLQFLHDHNCRSAERNQQRLNELRTAVAATHDSALWKTANLMIATTIEMLATLRTSIEQFNDQIQEVYEIHPDRFLMESLPGAGKALEPRLIAAMGTDRDRFRSAGDMACCFGIAPVTESSGNSRWVHWRWQCSKFIRQTFHEWGACTVRKEGRARDHYERQRAKGKSHHAAVRSVAFKWIRILYRCWRDRVPYSEQRYLEALARAAGKGKPAVNPAESSVSLPAVQWKTCGGFSKPTKLSS
>NC_008536.1|WP_095211922.1|2815526_2817623_+|ankyrin-repeat-domain-containing-protein
MGQARDFGPPCVLRPDRSWMNSVWWATSAKPGMSPRHCDPTMPDSIAGNSPAWSKAAACRTWAPGGARAVRFTSNRSSASSPAGRRPYASATTISSPIASPGPPTAQWTAAKPGPKKTRRSRRTALARRVRSARWRPRDSLAGMPENPISDPRSEFINVSVWHGSLDRAREILSAHPEVASSDIHTAALLGDHEAVARFLAEDPATATAKGGPRNWDALTYLCFSKFLRLELVRTPGFLKSAAVLLDAGANPNTGFFEENHQPKPEWECALYGAAGVAHHPELTKLLLDRGADPNDGEVAYHSPETLDNRTIHVLVQSGRLTQDSIGLMLARKFNWHDDDGVHWLLEHGADPNWPLRGSRPLHYALRHGTPIHYFEWLLDHGADPLLPDKNGTVPAGEAARLGRADVLELFERRGVVIALEGDDEFLAACARANAGEARKLAAANPSVVERMQSQNPGMLADFAGTGNTAAVRLMLDLGFDAGMARVQPNWVAGETALHVAAARGRQAVAELLIERGAPLEARQQRGWTPLRVAFLCLEQQSEWTPNEYTLPIAEALIKAGASVEAAGLTLTAAVCLGRGDDIARLAKKADAEEKQKALAAAAYNGSVDAIDAALALGADPNAPNGGAQSQRDRAAQCRLLRVAGRGEETRGYGSSCGCEGWAVPGYAARVGGVLRARESGEQAVRRDRAVFAREGEF
>NC_008536.1|WP_095211921.1|2815276_2815528_-|hypothetical-protein
MFFRDRSEFPLAKQVVEVAFVRVEQRAEFLVSLLYRRLRRHQNYEQRADQQTKCGHASRLSAALPDANKLQRAARRVQPAVMA
>NC_008536.1|WP_011683958.1|2814110_2815244_-|signal-transduction-histidine-kinase-LytS
MAALASAQPNRRRTQLPGFALILAAWLVPAMLSAFDSYMQSRLDNQQPDWRWVFFSGFDWLLYAVLTPAVFRISRSFPLQRDGLARRIALHIACALGMCVVWATLGQFLRLAIFHPPAGFTMTKFARALEGWIFTTLPFGTGVYFALVGIEHALAYMAQARERETQAVRLTAQLAEARLGALRMQLNPHFLFNSLNAITVLVRDQNTAAAARMLELLSDVLRSVLRAEGAHVTPLSTELEFLERYLAIEQVRFSDRLRPRIAVDPSLRRAAVPQFILQPLVENALRHGISRRADAGLLEVTAQRDGDMLVLTVRDDGPGLSPVEPLGTGVGLANTRARLAALYGDRASLEIASGAGAGVLATIRLPYHEAENHGGAE
>NC_008536.1|WP_011683957.1|2813359_2814127_-|response-regulator-transcription-factor
MAGQSEIRVLVADDEPLARRGVRQLLAPHRDMTVVGEARNGRETLTAIDALSPDLLFLDVQMPEMDGFEVLRARGPHRMPAVVFVTAHDQFAVRAFEAHALDYLVKPLRVDRFEAALHRVRERLRLMEAVDLAARLTALLETKREKCGVEWLVVPVATGELVIPVAEIDWIGADDYYACLHVGAKSYLLRESLASLETRLDPRRFARVHRSAIVQIDRIRELHGDEVVLRGGMRVALSRRRRAAIDGLLRGAGVF
>NC_008536.1|WP_011683956.1|2812193_2813261_-|hypothetical-protein
MFLKSMLLCAAAFSAAFAGDESITQAKPGRGQDPLFLTITNGANNFLAVINTRTKETDYVPTGGFGGASGNAGGVAVSGNLAAAVNFGSTNVTIFVRHGNAMEPAQLIKTSSQPVSVAFGHNHLVVLGQTTAESFAVFGNTVSKDNDGVVQLAKGDKSAAQILTFDGGVVYSEKSGSVAELNLSTNGMAGISGPNRPIQLPNAPNNDTPYGMAARGGNVYVTIAHSNLEALVVNGQIMSLGAGPTPFKDGSGNIMHAPCWNALAGQFLFSSDSPGKQLYRYLVSDSNVFFDKAAAARLNGSPTDLAATDNLLGVIDGGDGTTSNVSLFDIDSEGELTLRFAVKIAGPINGSAIIG
>NC_008536.1|WP_011683955.1|2811654_2812197_-|sigma-70-family-RNA-polymerase-sigma-factor
MSVSFYMGLDIDLQALMARYQQGDSEAATALVHRLSPQLHRFFLVKVMSRPHADDLLQETWMRIHQVRHTYRCGQPVLPWLYAIARNIRVDHYRKSSRGEGREQPLESKHDIAASEPGQNRTPDFEALLATLPESQREVIAMLKISGMSLEEVARATACSVGSVKQKVHRAYEKLRKALS
>NC_008536.1|WP_011683954.1|2810974_2811658_-|DUF1109-domain-containing-protein
MRDRDIDDFLNRGAGPPPEVDPDLLDRLSATVHSGLLPVRPLPSPSVLTAGLVAICAAIAIAGGLALGPHGIQRMIALQIAIVFAVLAVFMVLSAAVTVAEVIPGRRRLVAPWILLPAGCVALAVVFGLLFSDPGTERFVPQGLTCLKAGLLFALPAGVAAGWLLRRGFAVSPGAAWFAAGTLAGLAGVGMLELHCANFEAPHIIVWHIAVVPLSALIGFLAARYRR
>NC_008536.1|WP_011683953.1|2809986_2810970_+|hypothetical-protein
MWKAIVLLCAGLLEARDRIAFIDFYGVKGMDTEAVRRALPFKEGDALDRKNIKRQGHETVTRVTGKDATDVAAICCDPQGDTYIFIGLPGTSSKKFVINPPPNGAVRLSKELSALEAQLEKAGEEAMLKGGDAVIEDDSQGYALAQDPKLRALQMELREYAVKHEAELLRTAAECSDAEQRAYAVEALGYAQQSSRQIAALMQASRDSSDGVRNDATRALGVLLRSNPGLAAQIPAATFIEMMKSGFWTDRNKACSVLQPMSEGRDPQLMARLRAEALDPLIEMARWRSEGHAACGKMILARIAGAKEADVPMLAFGPVEAVLELLK
>NC_008536.1|WP_011683962.1|2821146_2821566_-|YciI-family-protein
MRFMILIKATKDSEAGELPDEKMLTAMGKFNEELAKAGVLLAGEGLRSSALGARVRFSGTNRTVIDGPFAETKELVAGFWIWKVNSLEEAIEWVKRCPNPHYEETEVEIRRLFEMEDFGPALTPELREQESRLFGESRP
>NC_008536.1|WP_157675862.1|2821629_2822151_-|beta-glucosidase
MPDAPITTFGVTVVDSVGLQGNIYLLRPNTDALPKFERLKPVGAIYTSSLNIPPRSFLEGFPGVTDRYEWFAIDYHGTFWIEQPGKYRFLLASDDGSKLYIDNKVVIDNDGIHAVQTETGMINLKAGSHRIRVSYFQGPRAGVALVLGVAAPGELRWRIFNTKEFLPPHNPEN
>NC_008536.1|WP_011683964.1|2822296_2824255_+|hypothetical-protein
MLFLQLFLALAALAICCFAPGFLLVRRLRWSGLEKLCGAIALSLTLLWLAAWGVYVFAPSAQAGAYFGIVALCCAAGAVAWRDAAALFRIPRVRRAVAGYGFVLGWTLLVLGIIRVYSGAIWAGDWLEHFQRTLYFLHHFPRETPIYNDYLLPARPPMMNVLAAIFLGVTADRYEIFQLVFAFLNLLLFLPCCLAIPLVAPVRKVSVAPLAAIFAMNPAVMQNATYTWTKSLTAFFVIFAVYLYLAGWRKRDPVRMTAAFACLASGLLVHYSAGPYVVFFALHYLLVVFRTRKEKWRELAALAAVSGFLVLTWFGWSVAALGTKATFASNTSITPREQEHYEGGNFVKIAGNLFDSFVPAILQDPAKIHLYDQPYTPGMLRDHAFTIYQANVIFSMGAIGGPMVIWFLIQAFRRKGRSAERRFWLWLIGFSVIVGIAVVGERDFFGVGHLTLIPMEVLGLTLLSAQFFRSRVIAFSIIAGCAFDFALGVFFHARLQHLENTAQHRYYAGLSVRDGQFLIGMAGPDSLGGGSWRNWFAKRQPILCNSWLQAEEQYRPGDPALEAARPDFRQAMKEKLDEDQKYFRGWYRDHGGQVGFLGDIAGDNELPSVLLLLAAGGLLWKLREMATQIRGTVRKAYPTGPGKPRSSRGRHK
>NC_008536.1|WP_011683965.1|2824208_2824958_-|high-affinity-nickel-transporter
MPAQGDYLSTLLHQGQIGWSVMLLGMLAAFAFGAVHALSPGHGKTLVAAYLVGSRGTPRHAIFLGLMVTFTHTISVFALGLVTLYLSRFVLPETITPILGAISGITIVWVGAMLLYRRTIGRVHVHTAGLAHHHGDGRIHTHVPEEMSIGGLIALGASGGLVPCPSALVLLLTSVSLGRVAFGLTLLVAFSLGLAVVLSAIGLAVLYARHLLPDSKNLMRGRVVRYLPIASAAFIICVGLAMTWVSLGP
>NC_008536.1|WP_157675251.1|2824979_2825603_+|ribose-5-phosphate-isomerase-B
MRQVITAQDVPAGGELRVPVGTIVTSSAREVAAGRGVRIVEVAEDQLTALAPPERTIAIGSDHGGFRLKEALKPLLEGLGLQVRDVGVNEEKPADYPDIAHAVAKLVAGGTAARGVIIDGAGIGSCMAANKVPGIRAALCYDKASAKNGREHNDSNVLTLGARLLTQTQAEEVLRTWLETPFAGGRHQARVQKIMDVEQQYSKKASS
>NC_008536.1|WP_157675863.1|2825824_2826487_+|deoxyribose-phosphate-aldolase
MDPTIAALIDHTILKADATREDVVKVCREARQYSFASVCVNPYWVPLVRAELAGTPVKVCTVVGFPLGATSTEAKVCETAGAIRGGAQEIDMVINVGALRSGDTDAVRSDIQAVVKVAHEAGAIVKVILETALLNDDQKTLASRLCKMAGADFVKTSTGFSTSGATAHDIALMRAAVGPAMGVKASGGIRTLEDVQTMTAAGASRIGASASVKIVEATAA
>NC_008536.1|WP_011683968.1|2826509_2828255_+|SpoIIE-family-protein-phosphatase
MQATRKASVRFRERSELLDFLLEVSASITQTLDLDQLLANVAEMVQKVLPYDLFAILLYSERRRDLRIRYAVGHRDDVVRNLSIAEGEGITGTAAARREPVLVSDVRNDPRYLNTVDAVRTELAVPMTARGKLVGVIDLQSTRVDAYTEYDRALMRLIAARVSIAIDNARLYRRADRQNRTLKTLANISREFSSILDLNELLSKIASTMHDLIAYDAFSILSVDHEAKALKHLFSIRYDKRVNIDNVPLGKGLTGAAAESREVVRVHDTAKDPRYIASHADIRSEVAVPLILQDRVVGVMDLESDRVGYFNDDQVRTLALLAPQVASSVENARLYAELAQRERRMEQDLEAARELQRILLPDAAPEIAGLEAAVRLRPAREISGDIYDIFEQREGQTVIAMGDVSGKGAAAALYGGLMSGLLRTLAPRRPRPAELMKALNDALVERKVEARYVTLGVMLWDASTRRIVMANAGALPPMICRGTEILKIRVEGVPLGLLESREYEEVTFQAEPGDTIVLYSDGITDHVNAAGTEFGRGRLAQIVRAHCGGTADGLILKIFEELDKFSKVAFDDQSIFVMKVL
>NC_008536.1|WP_011683969.1|2828257_2829070_-|signal-peptidase-I
MTDVETSTDLKAPGFRTRIAELTDDVQRGFIAEWAVTIILLLFGTTTLIQAFVIPSASMVGTLLIGDHVLVDKLVYAPGGAVSSKILPYRDVRRGDIIVFRYPLNISQDYVKRAIGVPGDHIHFDNKQLFLNGKMVNEPYTVHSQQYPDVYRDNFPSGAHAMPLRPRAAEMIEKNVVDGELVVPPGYIFAMGDNRDDSDDSRYWGLVPRENIVGTPVIIYWSFEAPTQDLINGNVGVDHIIDVITHFFTKTRWSRTFKLIRGYPLGRASN
>NC_008536.1|WP_011683970.1|2829144_2830641_+|magnesium-chelatase
MSQATPELPHTLGALRTSSFSEEKLAQRSVKDEIRKNLICAIQRGETLFPGIIGYEDSVVPQVVNALLSRHNFILLGLRGQAKTRLIRQLTNLLDEWTPYLAGCEIHDNPYAPICRRCRDLVADQPDDAHIAWLHREQRYVEKLATPDVTIADMIGDIDPIKAARRGQDISDELTVHYGLLPRANRGVFAINELPDLAGKIQVGLFNIMQEGDVQIKGYPVRMPLDVLLVFTANPEDYTARGKIITPLKDRIGSEIRTHYPAVLEQGIAITEQEAWLERPSPVEVRVPDYMRRVVEQLAFLAREDKRVDKRSGVSQRLPISVLENVVSNAERRALKAKDDMAVPRVTDLYSAMPAITGKLELEYEGELKGGDTVARELIRASVGKIFNESFEGVNFANIIQWFDLGGSLKLDEGVSSAQMVQQLGGIQGLMEKTKGLNLSSNEPDAVRAAAAEFILEGLYAHRRIGRSEERGFSAEEKPARREQESRPERPNMRRPLN
>NC_008536.1|WP_011683971.1|2830648_2831881_+|VWA-domain-containing-protein
MKWIKYSKYTGEDMGIGAEDLLQALSDFLLQSGFNTQYMPMSEWNQHTLEDLKNAIQQALEQGKLFDEEALQEMMERLQKMTPEQMDKLLENLIQKMVDEGQITIEDPANQPAAGSGPGKDTKVKFEVTDKSLDFLGFKTLKDLLGSLGKSSFGRHDTRDLATGIESNGSTKHYEFGDTLNLDVSETLFSAIRREGAKVPLNLDYADLHVHQCEYQSSCATVLMLDCSHSMILYGEDRFTPAKKVAMALAHLIRTQYPGDSLRCVLFHDSAEELDISQLARVQVGPYYTNTRDGLILAQRLLNQERKDMRQIVMITDGKPSCLTLEDGRIYKNAFGLDPLVISKTLEEVNRCRKQGILINTFMLASDFGLVNFVQKVTEICKGKAYFTTPYTLGQYLLMDYMNRKTRTIH

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Crispr_ID: NC_008536_5

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_008536_5

3080164-3080251

Orphan

Consensus_repeat	Method
CAGCCACGATTGGCTGCCCCACAA	CRISPRCasFinder

1 spacers

The CRISPR arrays of NC_008536_5

>merge|NC_008536|5|3080164-3080251|CRISPRCasFinder
CAGCCACGATTGGCTGCCCCACAAAGGGGTTTTATTCCCTTAACGGCGCGCAGCGCCATCGCGACAGCCAGGATTGGCTGCCCCACAA

>NC_008536|5|5|3080164-3080251|CRISPRCasFinder
CAGCCACGATTGGCTGCCCCACAA	AGGGGTTTTATTCCCTTAACGGCGCGCAGCGCCATCGCGA
CAGCCAGGATTGGCTGCCCCACAA

Protein	Signature genes	Signature genes Name	Protein_function
NC_008536.1\|WP_011684183.1\|3087841_3088960_+\|VCBS-repeat-containing-protein	unknown	unknown	gnl\|CDD\|379232
NC_008536.1\|WP_011684179.1\|3082195_3084343_+\|xanthine-dehydrogenase-family-protein-molybdopterin-binding-subunit	unknown	unknown	gnl\|CDD\|224446
NC_008536.1\|WP_011684168.1\|3071457_3072471_-\|VWA-domain-containing-protein	unknown	unknown	gnl\|CDD\|274577
NC_008536.1\|WP_011684171.1\|3075685_3076315_-\|PEP-CTERM-sorting-domain-containing-protein	unknown	unknown	gnl\|CDD\|377877
NC_008536.1\|WP_011684170.1\|3074955_3075459_-\|GNAT-family-N-acetyltransferase	unknown	unknown	gnl\|CDD\|223532
NC_008536.1\|WP_041857677.1\|3089053_3091522_-\|FtsX-like-permease-family-protein	unknown	unknown	gnl\|CDD\|274576
NC_008536.1\|WP_011684172.1\|3076450_3077095_-\|hypothetical-protein	unknown	unknown	unknown
NC_008536.1\|WP_011684174.1\|3077641_3078478_-\|hypothetical-protein	unknown	unknown	unknown
NC_008536.1\|WP_041857676.1\|3085319_3085535_+\|hypothetical-protein	unknown	unknown	unknown
NC_008536.1\|WP_011684166.1\|3068472_3068871_+\|type-II-toxin-antitoxin-system-VapC-family-toxin	unknown	unknown	gnl\|CDD\|350220
NC_008536.1\|WP_011684169.1\|3072550_3074695_-\|radical-SAM-protein	unknown	unknown	gnl\|CDD\|224875
NC_008536.1\|WP_011684177.1\|3080774_3081236_-\|hypothetical-protein	unknown	unknown	unknown
NC_008536.1\|WP_011684182.1\|3086427_3087552_-\|AAA-family-ATPase	unknown	unknown	gnl\|CDD\|379114
NC_008536.1\|WP_011684180.1\|3084342_3085317_+\|molybdopterin-dehydrogenase	unknown	unknown	gnl\|CDD\|224238
NC_008536.1\|WP_011684176.1\|3080401_3080719_-\|hypothetical-protein	unknown	unknown	unknown
NC_008536.1\|WP_011684175.1\|3078579_3079959_+\|PhoPQ-activated-pathogenicity	unknown	unknown	gnl\|CDD\|337644
NC_008536.1\|WP_011684181.1\|3085635_3086424_-\|hypothetical-protein	unknown	unknown	unknown
NC_008536.1\|WP_063720805.1\|3081642_3082203_+\|(2Fe-2S)-binding-protein	unknown	unknown	gnl\|CDD\|224991
NC_008536.1\|WP_011684167.1\|3068875_3071230_-\|ABC-transporter-permease	unknown	unknown	gnl\|CDD\|274576
NC_008536.1\|WP_041857675.1\|3077094_3077532_-\|hypothetical-protein	unknown	unknown	unknown

Protein	Function_ID	Function_description	E-value
NC_008536.1\|WP_011684168.1\|3071457_3072471_-\|VWA-domain-containing-protein	gnl\|CDD\|274577	TIGR03436, acidobact_VWFA, VWFA-related Acidobacterial domain. Members of this family are bacterial domains that include a region related to the von Willebrand factor type A (VWFA) domain (pfam00092). These domains are restricted to, and have undergone a large paralogous family expansion in, the Acidobacteria, including Solibacter usitatus and Acidobacterium capsulatum ATCC 51196.	1.3209e-33
NC_008536.1\|WP_011684171.1\|3075685_3076315_-\|PEP-CTERM-sorting-domain-containing-protein	gnl\|CDD\|377877	pfam07589, VPEP, PEP-CTERM motif. This motif has been identified in a wide range of bacteria at their C-terminus. It has been suggested that this is a protein sorting signal. Based on phylogenetic profiling it has been suggested that the EpsH family of proteins mediate this function.	0.00437086
NC_008536.1\|WP_011684170.1\|3074955_3075459_-\|GNAT-family-N-acetyltransferase	gnl\|CDD\|223532	COG0456, RimI, Acetyltransferases [General function prediction only].	1.20869e-09
NC_008536.1\|WP_011684182.1\|3086427_3087552_-\|AAA-family-ATPase	gnl\|CDD\|379114	pfam13304, AAA_21, AAA domain, putative AbiEii toxin, Type IV TA system. Several members are annotated as being of the abortive phage resistance system, in which case the family would be acting as the toxin for a type IV toxin-antitoxin resistance system.	7.60712e-13
NC_008536.1\|WP_041857677.1\|3089053_3091522_-\|FtsX-like-permease-family-protein	gnl\|CDD\|274576	TIGR03434, ADOP, Acidobacterial duplicated orphan permease. Members of this protein family are found, so far, only in three species of Acidobacteria, namely Acidobacteria bacterium Ellin345, Acidobacterium capsulatum ATCC 51196, and Solibacter usitatus Ellin6076, where they form large paralogous families. Each protein contains two copies of a domain called the efflux ABC transporter permease protein (pfam02687). However, unlike other members of that family (including LolC, FtsX, and MacB), genes for these proteins are essentially never found fused or adjacent to ABC transporter ATP-binding protein (pfam00005) genes. We name this family ADOP, for Acidobacterial Duplicated Orphan Permease, to reflect the restricted lineage, internal duplication, lack of associated ATP-binding cassette proteins, and permease homology. The function is unknown.	0
NC_008536.1\|WP_011684166.1\|3068472_3068871_+\|type-II-toxin-antitoxin-system-VapC-family-toxin	gnl\|CDD\|350220	cd09872, PIN_Sll0205-like, VapC-like PIN domain of Sll0205 protein and homologs. Virulence associated protein C (VapC)-like PIN (PilT N terminus) domain of the Synechocystis sp. (strain PCC 6803) Sll0205 protein and other uncharacterized homologs are included in this subfamily. They are similar to the PIN domains of the Mycobacterium tuberculosis VapC and Neisseria gonorrhoeae FitB toxins of the prokaryotic toxin/antitoxin operons, VapBC and FitAB, respectively, which are believed to be involved in growth inhibition by regulating translation. These toxins are nearly always co-expressed with an antitoxin, a cognate protein inhibitor, forming an inert protein complex. Disassociation of the protein complex activates the ribonuclease activity of the toxin by an, as yet undefined mechanism. The PIN domain belongs to a large nuclease superfamily. The structural properties of the PIN (PilT N terminus) domain indicate its active center, consisting of three highly conserved catalytic residues which coordinate metal ions, in some members, additional metal coordinating residues can be found. Some members of the superfamily lack several of these key catalytic residues. The PIN active site is geometrically similar in the active center of structure-specific 5' nucleases, PIN-domain ribonucleases of eukaryotic rRNA editing proteins, and bacterial toxins of toxin-antitoxin (TA) operons.	7.53646e-30
NC_008536.1\|WP_011684167.1\|3068875_3071230_-\|ABC-transporter-permease	gnl\|CDD\|274576	TIGR03434, ADOP, Acidobacterial duplicated orphan permease. Members of this protein family are found, so far, only in three species of Acidobacteria, namely Acidobacteria bacterium Ellin345, Acidobacterium capsulatum ATCC 51196, and Solibacter usitatus Ellin6076, where they form large paralogous families. Each protein contains two copies of a domain called the efflux ABC transporter permease protein (pfam02687). However, unlike other members of that family (including LolC, FtsX, and MacB), genes for these proteins are essentially never found fused or adjacent to ABC transporter ATP-binding protein (pfam00005) genes. We name this family ADOP, for Acidobacterial Duplicated Orphan Permease, to reflect the restricted lineage, internal duplication, lack of associated ATP-binding cassette proteins, and permease homology. The function is unknown.	0
NC_008536.1\|WP_011684183.1\|3087841_3088960_+\|VCBS-repeat-containing-protein	gnl\|CDD\|379232	pfam13517, VCBS, Repeat domain in Vibrio, Colwellia, Bradyrhizobium and Shewanella. This domain of about 100 residues is found in multiple (up to 35) copies in long proteins from several species of Vibrio, Colwellia, Bradyrhizobium, and Shewanella (hence the name VCBS) and in smaller copy numbers in proteins from several other bacteria. The large protein size and repeat copy numbers, species distribution, and suggested activities of several member proteins suggests a role for this domain in adhesion (TIGR).	1.35889e-06
NC_008536.1\|WP_011684180.1\|3084342_3085317_+\|molybdopterin-dehydrogenase	gnl\|CDD\|224238	COG1319, CoxM, Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM/CutM homologs [Energy production and conversion].	9.3185e-61
NC_008536.1\|WP_011684175.1\|3078579_3079959_+\|PhoPQ-activated-pathogenicity	gnl\|CDD\|337644	pfam10142, PhoPQ_related, PhoPQ-activated pathogenicity-related protein. Members of this family of bacterial proteins are involved in the virulence of some pathogenic proteobacteria.	0
NC_008536.1\|WP_011684169.1\|3072550_3074695_-\|radical-SAM-protein	gnl\|CDD\|224875	COG1964, COG1964, Predicted Fe-S oxidoreductases [General function prediction only].	5.66328e-79
NC_008536.1\|WP_063720805.1\|3081642_3082203_+\|(2Fe-2S)-binding-protein	gnl\|CDD\|224991	COG2080, CoxS, Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS/CutS homologs [Energy production and conversion].	1.78935e-63
NC_008536.1\|WP_011684179.1\|3082195_3084343_+\|xanthine-dehydrogenase-family-protein-molybdopterin-binding-subunit	gnl\|CDD\|224446	COG1529, CoxL, Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL/CutL homologs [Energy production and conversion].	2.3186e-131

>NC_008536.1|WP_011684175.1|3078579_3079959_+|PhoPQ-activated-pathogenicity
MKLARSIALTLLIAISAVAADTALDRYVKKPDATYKYEIVNTVKGEGFTTYIVDLTSQTWRTPAEVNRTVWKHWLTIVKPDRVATSTGFLFITGGSVGRKAPQSANATYTENALVTHSVVAELQDVPNEPLRFAGETRDRNEDGIIAYTWVKFMKGGDEEWPLRLPMTKAAVRAMDTISAIMATPDAGGVKVEKYVVSGGSKRGWTSWATAAVDPRIAAVIPVSIDTLNLEKTFEHHYRVFGFFSEAVKDYVESGVMDWNGTPEYRKLLAVEDPYSYRERYTMPKYMIQAAGDQYFLPDSSRYYFDDLKGEKYLRYIPNTDHGLRNTDARESSLAFYQAFLAGTPRPQFSWKFEANGDIKVTSRTKPEAVKIWQAANPDARDFRLMTIGPAYQGSELQDQGGGVYVAHARPPAKGWTAYFVELTYPSGGKYPFKFTTAVRVNPDTEPFPAYKPDPEKRK
>NC_008536.1|WP_011684174.1|3077641_3078478_-|hypothetical-protein
MRVRWFAICALILAITVCISCSSGPTGPEKGTPAFYWQAARETFAAGDTTKTLEHLDKLLADHNEYSDRALTWSLVLTSGLAAGYTELADTYEIGGRVNKSDPSAFRRPMMNYRSIAGRLSLQFGENFAKFASVKGDTVPLAFGRPIGTAATAPGLTRIGKGMVMPAADLENTETKTLERNILLAACSAAGAPDDTAKLESLLKSPDATVPRPVFVMAMARALYNASQLYNNRKLDDPSKLTIFAERAQEAMKSVPDSKEAKELNVKIAETIKKNKRT
>NC_008536.1|WP_041857675.1|3077094_3077532_-|hypothetical-protein
MKLIAFTFFALAGIAAASGLQLKDLPAAVQKTVQEQTKGAGIKSISKETEKGVTQYEIETIVNGKHRDFNVDTKGGLVVVEEETSIDSIPPAAKAAIEKKVTGGKLGVVETVTRGSTTFYEASFTTNTGKKRAILVKPDGTETKD
>NC_008536.1|WP_011684172.1|3076450_3077095_-|hypothetical-protein
MRLLGLLLAAVATLAAQPAKEFQSNFTVNKKNLGITGNNPFFPLAPGYVLSYRHGKDTDTLTVLSEVKVIDGVQTRVVEDRELKNGALVELTRDYYAIDSATNDVYYMGEDVDVYKRGKVVSHEGSWLSGVKGAKFGLMMPGAPKIGHKFYQEQAPGVTRDRAEILSVNEKVTTPAGTFEHCVHTLEGRDHKWYAPGVGQIKDAEMLLIKYTSR
>NC_008536.1|WP_011684171.1|3075685_3076315_-|PEP-CTERM-sorting-domain-containing-protein
MKKLAVCAILMFAANATWASNLSISDFSFENYPAAGYTYSGSFSGYVPGWTFTSNTGLAAQGSGFNVPSTPDGTQAAFLQGNGGTVSQSIGGFDSSFLYTLNVWVGTRSSSGCCTGDAGVSFFVDGVQIGTTGILTSFTPFTLYTIPFTVATSGAHTLALTNVSLPGDNTSFVDDVSISGSASAAPEPATFALIGSAFLALGLTRRRRA
>NC_008536.1|WP_011684170.1|3074955_3075459_-|GNAT-family-N-acetyltransferase
MDVIIRPAADSDRDAIWSILEPTIRAGETYTLPRDLTRDQALLYWFSPGHEVFVADDSGHIVATYYLRANQQGGGAHVANCGYMTAPRATGRGLARLMCAHSLERARQRGFRAMQFNFVVISNLRAIRIWQDFGFETVGRLPQAFLHPTLGYIDALVMLRHLSPSVA
>NC_008536.1|WP_011684169.1|3072550_3074695_-|radical-SAM-protein
MHKPIKYAEKALTVAANAAWFVFDKFNQVGQNPGFVPRWSDKPLLKSWEKTKPPLGWPRQTDSLCPRCVPEIRQQILDGKTPLEVLYTDKPGEIKAQIIERDGKILMVKDCPIHGHFEDVMAIDTAFFKHLEDVFPGRDIRAHNDEKLHKHGSSTVTHGRGSVLTVDLTNRCNMMCDPCFMDANQVGFVHELSWEDIQTLLDNAVTIKPKRQMSVQFSGGEPTISPHFLKAVSYAREVGYTSVQAATNGIEFAKNPEFCRQAAEAGLRYAYLQFDGIGNAANEHRKVGNLFDVKLRAIENLYTNGVDIIPVITIVNGINNEQVGRIVQFALDNPKRIPFLSFQPVSFTGRDEAVTDERRAAQRYTLSHLAHDVKNMNGLGEPARDWFPISFMSTFSDWSDLVHGPQADWGQLSCGCHPNCGVGMAVMVDKETKERVPVTAFLHADQLAKDVARVNDAARGKWLSIIGMSMAVARNYDPFQAPTHFKLSDMMKKFDKTFGATGKSYGKVGKDRTFDDIEQRRRDRWNFLFIAGMWFQDLFNYDFRRTEQCIIPYATQEGEISFCAYNTGVGWRNIIEKMHMTATLTKWYEEHGKHEIFAGGKSVPLNSKDHSMVIRDGIVTTEVQHDLEKLGIAKNSREEKIAARDAKIKQDAENARMAKLYREHILKEQPGPELVSIAPIGIAPAPAAAPLVQLAKPAAKKKVEEKEEVGSFGD
>NC_008536.1|WP_011684168.1|3071457_3072471_-|VWA-domain-containing-protein
MRIAATLLLLASAASAQFKSTVPLVLAPTTVKDSKGRYVDGLTAEDLSLYDDSVPQAIQMDWTTYPIDVVVAVQTSANSGAVIDKLGGSGILFTQLLAAESGETAVISFSDEVRLHQDFTGNPDSVIHALRMLRKEGGNAHMLDALRQALQMLEKRPPGRRRIVLMIGEKRDRGSDAKLPAVVEQVQRLNAAIYWLTYSPMLEPFTVKPKTAEDLKPEAERIKMRQCAACPPPDTTPVPPDLGPGGFIYALGELVHLRKPDLSTLFTQTTGGRTMSFLKKNALEQAIQLLSEEVHRQYILNFAPKNSEPGKFHTLRVAVKNRPDLQAKTREGYWAVD
>NC_008536.1|WP_011684167.1|3068875_3071230_-|ABC-transporter-permease
MDFRIALRTLCRYPAFTALAVVTLALGIASTTAIFSVVKAVLLTQLPYRDPDRVMALSQVGEWTAHELPTRTQSIESISLYGDTQRTLVDNGDPEVLRGLRVTHEFFETLGATMALGRTFTPAEDRWPRANVVILNHPLWVRRFASDPRIVGRVLQLTGEPYLVIGVLPPDFQPLRMSNPAEKPQIFMPAGYEPHRTALCRGCLDARAIARLRRGITLADARTDLNAAMREIVRQYPADFAPDISIRIAPLRDRMIAPILTPLYVLSAAVCALLLIACANLTSLLLARVTARSPELALRAALGAGRARIAAHLLTESLILSLAGGAAGALLAWPAIAILTSLAPRELPRLDEIHLDSSVLLFALGASLFAGLSVAIVPAWRAVRIDLNRELKRPARGGLRNLLVVAEIAMAFVLGVGAALLGKSLLRLTAVDSGFDPHHILTLTLSLSPNRYRTQDGARQYYRQVEQNLRAVPGVLDIGLVDNVPLSHTIPVKFRLSAGDTSASAADLFRASPGYFRVLKIPLRRGRLFTGQDGVTGPPTVIVSESFARSQFPGTDPIGQSIQLGPVNEHRPWLTIAGVVGDVRQEGLDRAPDQAIYIPQAADPLDYIRLLVRTTGDPLRSERGIRNAVRLADPDQPVFHVQPMDDYVASSLADRTFTLTLISLFGSIALLLAAIGIYGVISHTVGLRTRELGIRMALGAARSTVVRMILRDVLILLVSGLTAGVLAALALTRFLSHLLFEVRPTDITTAAGVALLLACVALLAASLPTLRAAAIDPNLALRSE
>NC_008536.1|WP_011684166.1|3068472_3068871_+|type-II-toxin-antitoxin-system-VapC-family-toxin
MTPQFLLDTHILIRWLSEPKKLSREQFRALEDVVRRGEYVCVSGFSLLEIALLGERRRITAGLNELFHELDTNPSIRILSLTTDVVREVSALGDALRDPADRVIVATARIHRLRLVTADQRIIASKLVGVIE
>NC_008536.1|WP_011684176.1|3080401_3080719_-|hypothetical-protein
MLPSLGFNRPFPAPSLTVFVALQVLDMLTTLLGLQLGAKEASLFLGNLMRVGPVAALLIAKIMAVLLISAALKYKRPRVVVFLNYWFAAVVTWNLGMILTTELSR
>NC_008536.1|WP_011684177.1|3080774_3081236_-|hypothetical-protein
MRKLLLFCTLTLSAAWAQDRPELNGTWHLDPARSAFSDMKLKAQTITIHQEDESIKIADAATEDNGKERKLEYECNTNGKECALKLNGQPFKVSAYYNGAVLVLMEQRKSSDATTRKRLKTSEDGKTLTIEIANLARPGQKPDSLVYAKSAEK
>NC_008536.1|WP_063720805.1|3081642_3082203_+|(2Fe-2S)-binding-protein
MGIGTGAVGAGILEREAIAAPAPANVVGPGAVPITLSINGKPVSLTVEPSVTLLDALRNHLDYTGAKKVCDRGTCGACTMIVAGKTVYACSVLAIDAQGKTIETIEGLPVNNPISTAFVNHDAQQCGYCTPGFVMATKGFLSEHPNPTVEDVKHGLGGNLCRCGTYMGIRQAVVEAAKNMKGAKNG
>NC_008536.1|WP_011684179.1|3082195_3084343_+|xanthine-dehydrogenase-family-protein-molybdopterin-binding-subunit
MANTPDYSWPPMADRKIMGKPFKRLDGPLKAAGRAKYTSDLKMKDMLFAAYVLCPHGHARVTAIDTSAAEKMKGVMSVHVIAPAGTEVQWHGKEIAALAATTEEIAREAIRKVKVDYEVLPHFVNEADLGKAGSRGKAAGEKVTGDPEKAFQDAEAVSDGVYGIPVVTHSCLEPHGCVIQWQGDQVMAWPSTQFVTGWANTLAPNLKVPAANIKVKMDYIGGGFGSKFSPGAWAEIGAILSQKAGGKPVKIYLDRVAEQTIAGNRPSAFGKIKVAGKKDGTITAWQSDTWASGGFAGGGQPPLPYVYTNIPNTRLNHTSISVNAGPSQAWRAPNNQQASYLTCSAIEDFAAKAGCDPMDVFHKNAGYTPRAEQYQYQLGKAAELSEWKKLWKPRGQQTGAVRRGLGIGVNAWAGNGHGCTSRVTINSDGSVLVEMGTQDLGTGTRTIMTQVAAETLGLSMGQVKLVIGDNSLPPGGSSGGSTTVGGVSSATRKAGINALAKLYEVAAPALGVQPDDLEAVDGNIRSKSNHAKTMTWAAACKKIPAAQGKIVETGANDTRNPMGLFSGGAAGVQVADVSVDTETGLVKINRFVAVQDCGLIINPRLAESQIFGAIIMGISTALFEERIMDNNTGRMMNPDLEFYKLAGIKDIGDIVVHLDIREVNDKRGVIGLGEPPAIGICAAVGNAVANAVGMRVPNMPMSPMNVLNTLEGRNA
>NC_008536.1|WP_011684180.1|3084342_3085317_+|molybdopterin-dehydrogenase
MQSFEYANPATVQEAVALLSAKWGEADVLAGGTDLISLMKDHLHTPKRVVNIKNIKELEGIQKTATGIRIGALVTMDELAKNADVKAAAKSLSDAAAGIPSPQIRHMGTVGGDLCQRPRCWYYRQGFGLLAMKDGKSLVPDGANQYHAIFGGGPAYFVSASSLGPALIALGAKVKLVSAKGPREVPASAFFVVPQNETSREIALHPDEILTEIVIPTATVKSATYEVRQKEALDWPLAAASVVLTMRGNTVASAKVVLGHVGPKPVESAEAAKAITGKAITADTAEAAGKAAVAGATPLSQNAYKVTLARVAVKRALLEAAKKA
>NC_008536.1|WP_041857676.1|3085319_3085535_+|hypothetical-protein
MERPGLTKVSMNRCEKLQWKGMFIDAEWDPTIQHSNDRSFWCQHTWNCCGPDGKVVDEFECSPGRSCYQPL
>NC_008536.1|WP_011684181.1|3085635_3086424_-|hypothetical-protein
MPIPTMTEAEIISYLERTQLPTVLVEGKDDASIYRWIEKRLGVMSGSVLICSGRDVLLSIYRKRHQFSHASIAWLADRDMWLYTCPPEDLGDVVFTAGYSIENDVYAGSEIESLLDGSELDSHRRLLATLSRWFAFEVAEFRGCRETRQAIHINRIVDFGNMDLIPAFIVDRGYSEPDAAIVNDVLTNYKLYLRGKTLLQAIVHFLSESNRTPKYSHAAVLDMSLRLYPANPYIKRIVQEVQYQLSPDTKQSPQWNVAGISG
>NC_008536.1|WP_011684182.1|3086427_3087552_-|AAA-family-ATPase
MIKSLKAVQLNRRMTFELSFHPDLNVVTGKNGSGKTTLLKLLWYVISGNLERIIPEITFESFDLVTDEFEVGMSIEGSGKQRIAKLRYRAGDFIKETERPFELSFDWDDLEITNREIVNTTSTSIFFPTFRRIEGGFSIPSRDEDSVRFNARLRSRETSHYRADSEHNALQRAMDQLSARLTVQQHRFVASISTHDIVRLLTSQYAEVSETTNRLHMDLSNFILKTIRGVSGEESRHLLSEIQTRARSVTERSELLLRPFTVLSGLIAQVFQYKGIKLADPITLGEAREAIASDLLSAGEKQMLSFLCYNAFANQASIFIDEPEISLHVDWQRILFPLLLDQSTGNQFIIATHSPFIYSKFADKELALSSDRGE
>NC_008536.1|WP_011684183.1|3087841_3088960_+|VCBS-repeat-containing-protein
MLRILLVLLVAALSAADFPQWKESTVTSSLKMGYQLVAVDLNRDGRPDLIAVDERGTELAWYENPTWERHVIIRDVPRTINLDVYDTDGDGIPEIAMGHNFETVPEKSIGNVLILKSGPDPRQPWTAREIDRIPTVHRLRWIDLKGDGKKVLLVAPMIGAKATPPEYADTVPVYLYRPGEWKRELYTALPRGILHSITPVHWQGRGEQLMTADFLGIRVFLPQGPVEISKGDPRPCPQCGSSEIKIGRLGKRRFIAAIEPWHGNQVVVYTEEGRAWKRHVLEDGMINGHALAVGDLNGDGRDEIVAGFRGAGFQLYIFTADDATGSRWTRRILDSGGMAAADCKIADFNGDGRPAIACSGASTANVKLYSPR
>NC_008536.1|WP_041857677.1|3089053_3091522_-|FtsX-like-permease-family-protein
MNEIGIFSRDVKYALRSLVATKGLTITVVLTLALGIGANAAIFTLVRGVLLRPLVNRDEDRLIYIHQSAPGMGLDNAVFSVPEILDLKQRVKTLSAIGDFSTIGFTMIGLGEPREVQAGVVGGTYFDVMGLHPVLGRLLDMRDDGPAAAGAVVLTYRYWTTALKSDPAVLGKVLRLGSRSATIVGVLEPSIPYPAETEIIANIVTSPHHLSATMVTGRLHRMTELFGRLAPGATLEQARAELKAAHATMVKDHPESYPVKADFRIDAVLLRDQITSKARTVLWVLLAASGLIFIIACSNVANLILARTIRREGELAIRAALGASTGALRRVLLTECLLLCGAGAALGILSARPMVAILARYASRFSVRALDLTVDSSMLWVGAGLALAAAALLAFVPRLPSGDGSSGINLSSGSLRMTGGASRRLRAFAITQIAASFVLLAGAAMLLKALLALQAVNTGIDTRRVLAINVPVMSYGKTDGQVVDFYKEAIRRIHQLPGVDGAALGMLTPWREGGNLGIGLQFTAEGYVRGTSEDDPRGQFRVVSPGFFAALGVPLIAGRDFNELDRKDAEPVAIVSQSVAQRMFPNRDALNRHVVWTDPVLKFISTKPAAPMRIIGIAKDIDDEHLVPGPTLTVYQPFGQGPMFGGRLFVHVRTDPYSLVTPITRTIREMSVEQPVERAATLEDVRAEVLTPNRLNALVFGGFALVALTIAVVGVAGVLAFSVSARTREFGIRLAIGSQPRHLLGRVIGEGTVITALGIGAGLACGLALQRLAARYFEIVDMPGAWVVLGAAGILLAAAVVASAWPAMRAARVDVIQALRAD

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Crispr_ID: NC_008536_6

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_008536_6

3616405-3616488

Unclear

Consensus_repeat	Method
GCGACCGTCAGGGAGCGATCTCC	CRISPRCasFinder

1 spacers

The CRISPR arrays of NC_008536_6

>merge|NC_008536|6|3616405-3616488|CRISPRCasFinder
GCGACCGTCAGGGAGCGATCTCCAAGTCCCCCGCCTCTCCTCAAATCCCTCAATCAGAGCTGCGACCGTAAGGGAGCGATCTCC

>NC_008536|6|6|3616405-3616488|CRISPRCasFinder
GCGACCGTCAGGGAGCGATCTCC	AAGTCCCCCGCCTCTCCTCAAATCCCTCAATCAGAGCT
GCGACCGTAAGGGAGCGATCTCC

Protein	Signature genes	Signature genes Name	Protein_function
NC_008536.1\|WP_011684614.1\|3624703_3625735_+\|aldo/keto-reductase	unknown	unknown	gnl\|CDD\|381317
NC_008536.1\|WP_083783732.1\|3622048_3622210_+\|DUF3309-domain-containing-protein	unknown	unknown	gnl\|CDD\|379538
NC_008536.1\|WP_011684606.1\|3614418_3615207_+\|acyl-ACP--UDP-N-acetylglucosamine-O-acyltransferase	unknown	unknown	gnl\|CDD\|100042
NC_008536.1\|WP_011684610.1\|3619883_3620933_-\|alcohol-dehydrogenase-catalytic-domain-containing-protein	unknown	unknown	gnl\|CDD\|176201
NC_008536.1\|WP_011684599.1\|3608172_3609201_-\|UDP-3-O-(3-hydroxymyristoyl)glucosamine-N-acyltransferase	unknown	unknown	gnl\|CDD\|234858
NC_008536.1\|WP_011684598.1\|3607557_3608172_-\|hypothetical-protein	unknown	unknown	unknown
NC_008536.1\|WP_011684604.1\|3612710_3613871_+\|hypothetical-protein	unknown	unknown	unknown
NC_008536.1\|WP_011684609.1\|3619206_3619764_-\|DUF1697-domain-containing-protein	unknown	unknown	gnl\|CDD\|377954
NC_008536.1\|WP_011684608.1\|3616684_3619159_+\|sodium-translocating-pyrophosphatase	unknown	unknown	gnl\|CDD\|234827
NC_008536.1\|WP_011684616.1\|3626784_3627543_-\|SDR-family-oxidoreductase	unknown	unknown	gnl\|CDD\|379263
NC_008536.1\|WP_041857780.1\|3625821_3626766_-\|ROK-family-protein	unknown	unknown	gnl\|CDD\|366120
NC_008536.1\|WP_157675304.1\|3610000_3610987_-\|DUF483-domain-containing-protein	unknown	unknown	gnl\|CDD\|367955
NC_008536.1\|WP_157675305.1\|3622375_3623242_+\|tetratricopeptide-repeat-protein	unknown	unknown	gnl\|CDD\|274350
NC_008536.1\|WP_011684611.1\|3620929_3621880_-\|aldo/keto-reductase	unknown	unknown	gnl\|CDD\|381297
NC_008536.1\|WP_011684603.1\|3612156_3612468_-\|hypothetical-protein	unknown	unknown	unknown
NC_008536.1\|WP_041857779.1\|3615232_3616369_+\|DUF2029-domain-containing-protein	unknown	unknown	gnl\|CDD\|378217
NC_008536.1\|WP_011684613.1\|3623251_3624451_+\|FtsX-like-permease-family-protein	unknown	unknown	gnl\|CDD\|182528
NC_008536.1\|WP_011684600.1\|3609286_3609928_-\|class-I-SAM-dependent-methyltransferase	unknown	unknown	gnl\|CDD\|379312
NC_008536.1\|WP_011684602.1\|3610983_3612153_-\|radical-SAM-protein	unknown	unknown	gnl\|CDD\|223714
NC_008536.1\|WP_011684605.1\|3613892_3614471_+\|PEP-CTERM-sorting-domain-containing-protein	unknown	unknown	unknown

Protein	Function_ID	Function_description	E-value
NC_008536.1\|WP_083783732.1\|3622048_3622210_+\|DUF3309-domain-containing-protein	gnl\|CDD\|379538	pfam14283, DUF4366, Domain of unknown function (DUF4366). This family of proteins is found in bacteria and eukaryotes. Proteins in this family are typically between 227 and 387 amino acids in length.	0.000245439
NC_008536.1\|WP_011684606.1\|3614418_3615207_+\|acyl-ACP--UDP-N-acetylglucosamine-O-acyltransferase	gnl\|CDD\|100042	cd03351, LbH_UDP-GlcNAc_AT, UDP-N-acetylglucosamine O-acyltransferase (UDP-GlcNAc acyltransferase): Proteins in this family catalyze the transfer of (R)-3-hydroxymyristic acid from its acyl carrier protein thioester to UDP-GlcNAc. It is the first enzyme in the lipid A biosynthetic pathway and is also referred to as LpxA. Lipid A is essential for the growth of Escherichia coli and related bacteria. It is also essential for maintaining the integrity of the outer membrane. UDP-GlcNAc acyltransferase is a homotrimer of left-handed parallel beta helix (LbH) subunits. Each subunit contains an N-terminal LbH region with 9 turns, each containing three imperfect tandem repeats of a hexapeptide repeat motif (X-[STAV]-X-[LIV]-[GAED]-X), and a C-terminal alpha-helical region.	8.45457e-122
NC_008536.1\|WP_011684610.1\|3619883_3620933_-\|alcohol-dehydrogenase-catalytic-domain-containing-protein	gnl\|CDD\|176201	cd08239, THR_DH_like, L-threonine dehydrogenase (TDH)-like. MDR/AHD-like proteins, including a protein annotated as a threonine dehydrogenase. L-threonine dehydrogenase (TDH) catalyzes the zinc-dependent formation of 2-amino-3-ketobutyrate from L-threonine via NAD(H)-dependent oxidation. The zinc-dependent alcohol dehydrogenases (ADHs) catalyze the NAD(P)(H)-dependent interconversion of alcohols to aldehydes or ketones. Zinc-dependent ADHs are medium chain dehydrogenase/reductase type proteins (MDRs) and have a NAD(P)(H)-binding domain in a Rossmann fold of an beta-alpha form. The N-terminal region typically has an all-beta catalytic domain. In addition to alcohol dehydrogenases, this group includes quinone reductase, sorbitol dehydrogenase, formaldehyde dehydrogenase, butanediol DH, ketose reductase, cinnamyl reductase, and numerous others. These proteins typically form dimers (typically higher plants, mammals) or tetramers (yeast, bacteria), and generally have 2 tightly bound zinc atoms per subunit. The active site zinc is coordinated by a histidine, two cysteines, and a water molecule. The second zinc seems to play a structural role, affects subunit interactions, and is typically coordinated by 4 cysteines.	1.41709e-179
NC_008536.1\|WP_011684599.1\|3608172_3609201_-\|UDP-3-O-(3-hydroxymyristoyl)glucosamine-N-acyltransferase	gnl\|CDD\|234858	PRK00892, lpxD, UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase; Provisional.	6.0911e-130
NC_008536.1\|WP_157675304.1\|3610000_3610987_-\|DUF483-domain-containing-protein	gnl\|CDD\|367955	pfam04467, DUF483, Protein of unknown function (DUF483). Family of uncharacterized prokaryotic proteins.	0.000401337
NC_008536.1\|WP_041857779.1\|3615232_3616369_+\|DUF2029-domain-containing-protein	gnl\|CDD\|378217	pfam09594, GT87, Glycosyltransferase family 87. The enzymes in this family are glycosyltransferases. PimE is involved in phosphatidylinositol mannoside (PIM) synthesis, a major class of glycolipids in all mycobacteria. PimE is a polyprenol-phosphate-mannose-dependent mannosyltransferase that transfers the fifth mannose of PIM. The family also includes alpha(1-->3) arabinofuranosyltransferase, invloved in the synthesis of of mycobacterial arabinogalactan.	4.96189e-10
NC_008536.1\|WP_011684608.1\|3616684_3619159_+\|sodium-translocating-pyrophosphatase	gnl\|CDD\|234827	PRK00733, hppA, membrane-bound proton-translocating pyrophosphatase; Validated.	0
NC_008536.1\|WP_011684616.1\|3626784_3627543_-\|SDR-family-oxidoreductase	gnl\|CDD\|379263	pfam13561, adh_short_C2, Enoyl-(Acyl carrier protein) reductase.	5.0691e-56
NC_008536.1\|WP_041857780.1\|3625821_3626766_-\|ROK-family-protein	gnl\|CDD\|366120	pfam00480, ROK, ROK family.	3.3973e-59
NC_008536.1\|WP_157675305.1\|3622375_3623242_+\|tetratricopeptide-repeat-protein	gnl\|CDD\|274350	TIGR02917, TPR_domain_protein, putative PEP-CTERM system TPR-repeat lipoprotein. This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.	1.43883e-13
NC_008536.1\|WP_011684611.1\|3620929_3621880_-\|aldo/keto-reductase	gnl\|CDD\|381297	cd19071, AKR_AKR1-5-like, AKR1/2/3/4/5 family of aldo-keto reductase (AKR) and similar proteins. Aldo-keto reductases (AKRs) are a superfamily of soluble NAD(P)(H) oxidoreductases whose chief purpose is to reduce aldehydes and ketones to primary and secondary alcohols. The family includes AKR1A/B/C/D/E/G/I, AKR2A/B/C/D/E, AKR3A/B/C/D/E/G, AKR4A/B/C, AKR5A/B/C/D/E/F/G/H, and similar proteins.	1.31835e-104
NC_008536.1\|WP_011684614.1\|3624703_3625735_+\|aldo/keto-reductase	gnl\|CDD\|381317	cd19091, AKR_PsAKR, Polaromonas Sp. aldo-keto reductase and similar proteins. The prototype of this family is an uncharacterized aldo-keto reductase from Polaromonas sp.	4.00629e-172
NC_008536.1\|WP_011684609.1\|3619206_3619764_-\|DUF1697-domain-containing-protein	gnl\|CDD\|377954	pfam08002, DUF1697, Protein of unknown function (DUF1697). This family contains many hypothetical bacterial proteins.	1.10806e-49
NC_008536.1\|WP_011684613.1\|3623251_3624451_+\|FtsX-like-permease-family-protein	gnl\|CDD\|182528	PRK10535, PRK10535, macrolide ABC transporter ATP-binding protein/permease MacB.	1.47974e-56
NC_008536.1\|WP_011684600.1\|3609286_3609928_-\|class-I-SAM-dependent-methyltransferase	gnl\|CDD\|379312	pfam13649, Methyltransf_25, Methyltransferase domain. This family appears to be a methyltransferase domain.	2.66927e-11
NC_008536.1\|WP_011684602.1\|3610983_3612153_-\|radical-SAM-protein	gnl\|CDD\|223714	COG0641, AslB, Arylsulfatase regulator (Fe-S oxidoreductase) [General function prediction only].	2.92509e-25

>NC_008536.1|WP_041857779.1|3615232_3616369_+|DUF2029-domain-containing-protein
MRIPLILACALGIAVNCFLYRPVLGYILHGNNDFVCYYAAAQLSGSPALYDEPAMRRTEIALGDHQHAVVFTRLPFYAAWISPLRFFDFDLAYLLWQALSLSGVLLFIWFWPSGDRGLNALVCCWSLPLLEAFISGQDVTLLLAALAVSMWLRARGRDFAAGCALAVCSVKYHLFLTLPLLLLARRMGRFTAGLVAAGAALAVWSFAVAGWSWPRPYIAILTRPDTTPDWNGMPNLRGLFVGLPNDRLWELLGAALVLLAAWIVIRGKQEPLAIAATLASGLLLGHHAFLRDAVLLLPVCLLMWQSSCGAPCRAAALLMFSPLPYLLFLLPDPPLRPAVLIPLPLLVMAATTLYSQPSLLWGSQSWLPPAFSRRPRTR
>NC_008536.1|WP_011684606.1|3614418_3615207_+|acyl-ACP--UDP-N-acetylglucosamine-O-acyltransferase
MPIDSSAVVAHTARVSPEASIGPGVRIGEFCVVESDVVLGAGCILEPHVYIKRWTTLGERNEISAGAVLGTDPLDKNFKGERSYLTIGNGNKIREHFTISRGTPPESATTIGDDNFIMTSGHIAHNCKIGSNTVIASCALLGGYVEVEDHAFLSGGVLVHQYSKVGRLAMVSGNTRVNLDAPPFFTFAGFAIAPKGLNLVGLKRAGFDAPRISILKQAYRYLYRSNLKLDAALARIEDEIPTPDTLHLTAFIRSSRRGVCRE
>NC_008536.1|WP_011684605.1|3613892_3614471_+|PEP-CTERM-sorting-domain-containing-protein
MIKNVLSISVFALAVAALLPSAAAAPTSFCAPNFSSCNIFEDGQPLSLPGLAIAGDVVLLDRFTGTTSDVFRVFNDFFDTGGGTGLGVTAFLYSEDLHNLPNPATYSVNAVFINEAFGSGGGGTIETDYNGNGTIYRVFSVDDGSPEPSTFILFATGAALLAGRSRRANGLMIRNHAHRLFRRRRPHSARLA
>NC_008536.1|WP_011684604.1|3612710_3613871_+|hypothetical-protein
MKRLSSFTGVITVMVACGIAPAFGQTTIDIDGVTYNVATKYSRSLRAGPRQAAGLSVASGVVPNANLFGGLQFYTANYTSFGKSNAFNIVGTDPSLGAGTTTVPVVIVPIRLTFNSTGKVLDGTNQGAATVNSPIFLTADFTTGGTDVGVTQYGDAIQRAQFWNFSGFSPAGYHVLLGAPTVAPTISITVTTGNGTTNGSGTVGVVLDTFLDPLLTALVPSFGPNVLPIFLTDNVFESADGTFNTCCTLGYHASEGPPVVTAHTWIYAAYTRSGTFSGNVIQDVQPLSHEVSEWVNDPFVGAFPGINLIPPAVLPGQGGACIINFETGDPLEAPPVVFTEVTNGTTYHLQDEVFLWWYTHGPSFGVNGFFSYTGKFLTSSSLCGPG
>NC_008536.1|WP_011684603.1|3612156_3612468_-|hypothetical-protein
MSKSNPNTVRDVLKRAGFSDEFVADALRQRLNAGDHTDMGSGHSDFPKHQDLHLDIANRLDSRADAVSLTMSLELREGLNEWVRLIHGRIADLEKRLESLEKK
>NC_008536.1|WP_011684602.1|3610983_3612153_-|radical-SAM-protein
MIEVRPFGVKCNIRCRYCYQEPQRTFDSNRLYDIEAMKGSIVAEGGPFALFGGEPLLVPHADMEQLFAWGYERFGENGIQTNGSLIDDEHIRLFRTYNVRVGISLDGPGELNDIRWAGTLERTRAATSKSQQAVERLCQEGIIPSIIVTLHKQNATPERLPTLIAWMRDLALRGVTSVRLHLLEIDGPEVREHFALTTGENVNALMAFGQLQAEIPKLDLDVFSDMRRLLLGKDGAGHATTCVWNACDPYTTAAVRGVEGNGQRSNCGRTYKDGVEFVKAATPGYERYISLFHTPQEFGGCNGCRFFIMCKGQCPGTAIASDWRNRTEHCDVWKMLFTWMEAELLAEGNVPISLVPARKDVETILLEYWSRGANTTIEGALSERNLERA
>NC_008536.1|WP_157675304.1|3610000_3610987_-|DUF483-domain-containing-protein
MTHLNFSVPYFFRSMWTSDLARNQWEPRIRAIAAAISELQWRTVANDMRQCCIARVLSEQFEAKRHDFERHGLEVIPLSREVRGGPEYQSRVRPYVPGEPFQICVALGKHGAARDLAEAVRCESDDEAGTLLGYPGCCISSFLDDFRNSEYSDNTWSMARASVTGLSMLEDEGRTIRIDKASLANILLRGMGVRAVFHLPCRFDCSKSIECAEGVIRSGRGEGFRAEMEWLEEILNWPMEWNAMHGIAEIKTAVLKCSTSTAATAKAYRVLVMGTEFPELGAKGAGHVYHTSREALGRAALGPGRTGLPESTGKSGQSTSRRDSPDPL
>NC_008536.1|WP_011684600.1|3609286_3609928_-|class-I-SAM-dependent-methyltransferase
MSNTDRPGTPPLRLSRDQFYSKLREGYAQQYWGDRDGSDIFHPNGFPSLPTVIYDFFCEQIAHDGKVLDLGCGNGLMVRHLTERSRFRLIPYGVDFLGASIRQAQEVILPQFASHFSVGNLVNYPFPHAPYDFIFSSPDNVYPTDRSAFLDALPSKCARDGCVIFYSYRDMLTNSQREWVGEVPELSRLPLERKDGPEVSLGIWRVAGGCSGA
>NC_008536.1|WP_011684599.1|3608172_3609201_-|UDP-3-O-(3-hydroxymyristoyl)glucosamine-N-acyltransferase
MRVRELAEWLGATFEGDGERELTGVATLESAGTEEVAFVGNRKAAEMAEASAAGCLIVPMEWPSPAYRTVIRAAEPRTAFARAMNRFYPTAELKPGVHPTAVVGKDVEMAAMVYVGPHATVGDGTRIGVASSIGAGCIVGKRVQIAEGCVLHPNVTVYDNVDIGRGSVLHSGCVIGADGFGYVMEHGRWHKFPQVGRVEIGDFVEIGANSCVDRAALGVTSIGEGTKLDNMVHVGHNCRIGKHVVVAAQTGFSGGVVVEDYAVIGGQVGIGDKARIETRAVLGSGCGVLTSKIVRSGETVWGTPARPLKRHLEELASLGRLPELRKEMSDLKRRLAELERKA
>NC_008536.1|WP_011684598.1|3607557_3608172_-|hypothetical-protein
MLVVVGGHSRNIGKTGLAAGLIRRTRGMKWTALKITQYGNAVCSRHTVESTCGCEPGNGEEFALDEEFEANDTDSGRFLGAGAERSFWLRVPAGELPRAAGLVRKILAQGENVIVESNSVVELVQPDVFLMILDFSCEDFKPSSLRFMDRADGFVVIDRGINAPLWAEVAQGMWDGKPQFLVTPPRYATTEIVDFVKSKAAERA
>NC_008536.1|WP_011684608.1|3616684_3619159_+|sodium-translocating-pyrophosphatase
MFSTPDTLCVERCAANARIRSVLRVLMLVLSLVALGAPLMAQETGGGEANLKLPRLDSVTFLGGISGSSLLMGGLVVSALGLIFGLYIFTRLRAMPVHDSMREVSELIYETCKTYLATQGKFLCILEALIAVIIVFYFGFLLGFEFYKVLIILAFSVVGISGSFMVAAFGMRVNTFANSRTSFAALRGKPFPCYAIPLQAGMSIGMLLVSVELLIMLCILLFVPGDLAGSCFIGFAIGESLGAAALRVAGGIFTKIADIGSDLMKIVFKIKEDDARNPGVIADCTGDNAGDSVGPSADGFETYGVTGVALITFILLAVASPTVQVQLLVWIFTMRIMMVISSGVGYFINDAIAKAKYLNADKFDFEAPLTTLVWLTSILSIVLTYVLSNMMIPDLAGDTTLWWKLATIISCGTLAGALIPEFVKVFTSTNSRHVREIVTSSREGGASLNILSGFVAGNFSAYWLGMAMLALMSIGFFVSTMFPVTLMLAPAVFAFGLVAFGFLGMGPVTIAVDSYGPVTDNAQSVYELSTIETIPNIEALIQKQYGFKPEFEKAKENLEENDGAGNTFKATSKPVLIGTAVVGATTMIFSTIVALTHGLKDNMDKLSMMHAPFLLGLIAGGAVIYWFTGASAQAVTTGAYQAVEFIKKNIKLETTEKASVADSKKVVEICTKYAQKGMFNIFLVVFFSTLAFAFLEPFFFIGYLVSIALFGLFQAIFMANAGGAWDNAKKVVETELRAKGTPLHDACVVGDTVGDPFKDTSSVALNPIIKFTTLFGLLAVQLAVSVSAKQGNTLTTILSAVFFLASTYFVYRSFYGMRIETTKE
>NC_008536.1|WP_011684609.1|3619206_3619764_-|DUF1697-domain-containing-protein
MMVYISLLRGINVGGNNLVKMEALRALYEKLKFRDVVSYVQSGNVVFRAAETNRARIADRIEDAIEGEFGHRPRVVLRTTAELRDLMARNPFARRAGIEPGKLVVTFLAGELPDEARVKLESLPKTPEEMHLHVRELFTYFPNGMGQSKLSLAAVDRALKIPGTARNWNTVSKLLALAEGLEITP
>NC_008536.1|WP_011684610.1|3619883_3620933_-|alcohol-dehydrogenase-catalytic-domain-containing-protein
MIGAYLPGNSTVEMKEVPVPVPAHGEVLLRMKASTICGSDIRCIYHEHLGKGPEGYQGVVAGHEPCGQIVKTGPGCRRFGVGDRVIVYHISGCGVCNDCRRGYMISCTSERYRRAYGWQRDGGMAEFLLAEEKDLIPLPGKLSYADGAQVACGFGTVYEGLEKIGISGNDAVLITGLGPVGLATGALCRKLGAEKIIGIDVVPERMKLALDLKLCDEVLASGPENVAEVRRLTGGQGVERAVDCSANEQARATAIRATRKWGRIVFLGEGGRVEFNPSPDIIHDQKTIYGSWVTSTWLMEELVERLVRWNLHPADLVTHRFPLESVDQAYTLMASGKCGKVAVCFDEEL
>NC_008536.1|WP_011684611.1|3620929_3621880_-|aldo/keto-reductase
MPAIGLGTFGSDHVSAEQIADVVRDAAVVGYRHFDCASVYRNEDRIGFAFRDIMKGGIRREDLWITSKLWNDKHGEGDVIASCRQSLADLQLDYLDMYLVHWPFPNFHPPGCDVSSRSPDARPYIHENYMKTWREMERLVELGLVRHIGTSNVTIPKLKLILRDARIRPAVSEMEMHPHFQQRELFEFVRAAGIEPIAYSPIGSPGRPERDRTPEDTVDIEDPVIVAIAKRIGVHPAVVCVKWAEQLGATPIPFSTRRRNYLANLQGVVSDPLTAADMEAIAGIDRNCRLIKGQVFLWKQDQTWEDLWDLKGVIAQ
>NC_008536.1|WP_083783732.1|3622048_3622210_+|DUF3309-domain-containing-protein
MLILLIVVLVLLLGGGGGYYGYGRWGYGGGAGVGLGTILVILLCLYLFGFLHY
>NC_008536.1|WP_157675305.1|3622375_3623242_+|tetratricopeptide-repeat-protein
MSVALVKSWVVLISASVILSASGPDLERARKLYNLTEFEQSLQVLHSIPEKDGQVWELIGRNYYGEGDFKKATESLEKAVAAQPRSSETYLWLGRAYGRRAETSNPITAPGYASKARQNFERATQLNPDNLDAQSDLFEYYLEAPGFLGGGLEKARATADQMSRINPAEGHWALAKLAEKRKEYSSAEDQLRRAIEAAPHQVGRFIDLARLFTKQGRYQEADQSLAKAEQIAPNSPKLIFAKADLYIKSKRNLGVARELLKKYLSLALTPDDPSRSEAEKLLKQVQGS
>NC_008536.1|WP_011684613.1|3623251_3624451_+|FtsX-like-permease-family-protein
MFLGEAVRFSAQALRASPVRSLLTGLGMAIGTASVILVVTISLTSRDYILEQVQGIGSNIIFAYYANAGGSTVADADYIKMTDVHALRQELTADIVAATGVMSNFDRILIGGKEQDVKVIGTDQDYQPVRNIVISSGRFLDESDITLRGKTALLTDQLATRMFGGRAAALSQVIKLYGLEFTVIGTFHEKVETFGQSEVERDTILIPITVLRYFTPVERIDPLYVQVRSPQEVERVALRVQQILEARHRPGARYRVDTLTAILNAAKNISLILSLVLVLVSAITLVISGIGIMNIMLVTVTERTREIGVRLAVGASPREILLQFLAEAIMVSLTGGVAGILAGIAIPLSVQLFADIKIPISPVAIVVAFGVSCLVGLIFGILPANRAAHLHPTEALRYE
>NC_008536.1|WP_011684614.1|3624703_3625735_+|aldo/keto-reductase
MEYRLLGASGLQVSVLSFGTMTLGGEGRFAAMGNVQVEEARRQIEICIEAGVNLFDTADIYSFGKSEEVLGQALGALRKDIVLATKVFVGLEPGANKSGLTRRHIMEACEASLRRLGTDTIDLYQAHNFDALTPLEETLRAFDDLIRSGKIRYAGCSNYSGWQLMKAHSTSDRLAVQRYISQQINYSLLARDAEHELVPAGLDQHTGIMAWSPLQFGLLSGKFRRGQAKPSESRLNTLDAPGTIDEERLYRIVDALAEIAAVRNVSVSQVALNWVTCKPGVDTVIIGARTDQQLRDNLAAAAWRLTPAEVERLDEVSALPLPYPYWHQQKFAADRNPPLPHTR
>NC_008536.1|WP_041857780.1|3625821_3626766_-|ROK-family-protein
MVVLGIDIGGNQIRAGMVDADGAILASRTLPTPGDLDTFLPTLQDAIRWLMETTSLPEGVGVGCKGIIDPDTTRIEALPGTMHFLQGLRIADLVGLPLEVPVFADNDARVALAGEMVWGAARGHDNVLMLTLGNGVGGAAILNGRLLRGHSGVAGHMGHITIEPNGAVCACGNRGCLETVFSARAIEAEAQAAVLRGCDSVLTRLFREQPQLATCRTIFQAAREEDAVARAVIGRAIFKLGAALAGLLHLFDPEIVILGGSVADAGEDLIIPLQEEVWSRSRGLLGRDVPIVEQMVADKSGIVGAAGLVMAPRP
>NC_008536.1|WP_011684616.1|3626784_3627543_-|SDR-family-oxidoreductase
MREKVLIITGSTGIGAETVRMTAARGARIVIATGDEISGFELAAETGAECWAGDLTLANSADSVLTQCLSKFGRVDGLFNVAGLSGRRFGDGPVHEIQDDAWHTTLSHNLTLAFRMCRAVTGRMLEQEGGGAIVNMGSVLADSPEPRHFATHAYAAAKGAVAAMTKSMAAYYAPHGIRINLIAPGLVRTPAGERTQADPAFQEFVRKKQPLNSGMIEVAEVARAAVFLLSEESRSVTGEVFTIDGGWRLSGV

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Crispr_ID: NC_008536_7

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_008536_7

5199267-5199412

Orphan

Consensus_repeat	Method
ACAGTGCGGCGAGCGCAAATTGAAATTGTGGTGCGCGGGCTGCGAG	CRISPRCasFinder

1 spacers

The CRISPR arrays of NC_008536_7

>merge|NC_008536|7|5199267-5199412|CRISPRCasFinder
ACAGTGCGGCGAGCGCAAATTGAAATTGTGGTGCGCGGGCTGCGAGATCGCTTGTTAGTGCGGCGAATCTTCGCGGGCTGCGGACAGATGCACAGTAGTACAGTGCGGCGAGCAGCAAATTGAAATTGTGGTGCGCGGGCTGCGAG

>NC_008536|7|7|5199267-5199412|CRISPRCasFinder
ACAGTGCGGCGAGCGCAAATTGAAATTGTGGTGCGCGGGCTGCGAG	ATCGCTTGTTAGTGCGGCGAATCTTCGCGGGCTGCGGACAGATGCACAGTAGTA
CAGTGCGGCGAGCAGCAAATTGAAATTGTGGTGCGCGGGCTGCGAG

Protein	Signature genes	Signature genes Name	Protein_function
NC_008536.1\|WP_011685813.1\|5205157_5205973_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|372574
NC_008536.1\|WP_011685810.1\|5202952_5203483_+\|RNA-polymerase-sigma-factor	unknown	unknown	gnl\|CDD\|224511
NC_008536.1\|WP_011685802.1\|5191227_5192223_+\|acetamidase	unknown	unknown	gnl\|CDD\|225279
NC_008536.1\|WP_011685800.1\|5188802_5189387_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|225786
NC_008536.1\|WP_011685803.1\|5192234_5193689_+\|carboxypeptidase-regulatory-like-domain-containing-protein	unknown	unknown	gnl\|CDD\|379297
NC_008536.1\|WP_011685806.1\|5196368_5199104_+\|OmpA-family-protein	unknown	unknown	gnl\|CDD\|143586
NC_008536.1\|WP_011685816.1\|5207016_5207937_+\|phenylalanine-4-monooxygenase	unknown	unknown	gnl\|CDD\|237020
NC_008536.1\|WP_041858016.1\|5189402_5191112_-\|arylsulfatase	unknown	unknown	gnl\|CDD\|293761
NC_008536.1\|WP_011685814.1\|5206079_5206640_+\|sigma-70-family-RNA-polymerase-sigma-factor	unknown	unknown	gnl\|CDD\|236608
NC_008536.1\|WP_083783803.1\|5203389_5204289_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|379311
NC_008536.1\|WP_011685798.1\|5186846_5187632_-\|DUF2950-family-protein	unknown	unknown	gnl\|CDD\|371539
NC_008536.1\|WP_041858018.1\|5199453_5200635_-\|amidohydrolase-family-protein	unknown	unknown	gnl\|CDD\|236478
NC_008536.1\|WP_083783802.1\|5193851_5195264_+\|DASS-family-sodium-coupled-anion-symporter	unknown	unknown	gnl\|CDD\|279307
NC_008536.1\|WP_011685799.1\|5187642_5188773_-\|DUF3300-domain-containing-protein	unknown	unknown	gnl\|CDD\|378701
NC_008536.1\|WP_011685796.1\|5179683_5183139_-\|carboxypeptidase-regulatory-like-domain-containing-protein	unknown	unknown	gnl\|CDD\|379297
NC_008536.1\|WP_011685797.1\|5184231_5186592_-\|tetratricopeptide-repeat-protein	unknown	unknown	gnl\|CDD\|276809
NC_008536.1\|WP_011685808.1\|5200744_5201539_+\|rRNA-pseudouridine-synthase	unknown	unknown	gnl\|CDD\|224108
NC_008536.1\|WP_011685809.1\|5201775_5202696_-\|hypothetical-protein	unknown	unknown	unknown
NC_008536.1\|WP_011685812.1\|5204285_5205143_+\|hypothetical-protein	unknown	unknown	unknown
NC_008536.1\|WP_011685815.1\|5206632_5206950_+\|hypothetical-protein	unknown	unknown	unknown

Protein	Function_ID	Function_description	E-value
NC_008536.1\|WP_011685813.1\|5205157_5205973_+\|hypothetical-protein	gnl\|CDD\|372574	pfam13349, DUF4097, Putative adhesin. This has a putative all-beta structure with a twenty-residue repeat with a highly conserved repeating GD, gly-asp, motif. It may form part of a bacterial adhesin.	0.000187416
NC_008536.1\|WP_011685810.1\|5202952_5203483_+\|RNA-polymerase-sigma-factor	gnl\|CDD\|224511	COG1595, RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog [Transcription].	3.32105e-35
NC_008536.1\|WP_011685802.1\|5191227_5192223_+\|acetamidase	gnl\|CDD\|225279	COG2421, COG2421, Predicted acetamidase/formamidase [Energy production and conversion].	1.4297e-88
NC_008536.1\|WP_011685800.1\|5188802_5189387_-\|hypothetical-protein	gnl\|CDD\|225786	COG3247, HdeD, Uncharacterized conserved protein [Function unknown].	4.5888e-16
NC_008536.1\|WP_011685803.1\|5192234_5193689_+\|carboxypeptidase-regulatory-like-domain-containing-protein	gnl\|CDD\|379297	pfam13620, CarboxypepD_reg, Carboxypeptidase regulatory-like domain.	3.19202e-09
NC_008536.1\|WP_011685806.1\|5196368_5199104_+\|OmpA-family-protein	gnl\|CDD\|143586	cd07185, OmpA_C-like, Peptidoglycan binding domains similar to the C-terminal domain of outer-membrane protein OmpA. OmpA-like domains (named after the C-terminal domain of Escherichia coli OmpA protein) have been shown to non-covalently associate with peptidoglycan, a network of glycan chains composed of disaccharides, which are crosslinked via short peptide bridges. Well-studied members of this family include the Escherichia coli outer membrane protein OmpA, the Escherichia coli lipoprotein PAL, Neisseria meningitdis RmpM, which interact with the outer membrane, as well as the Escherichia coli motor protein MotB, and the Vibrio flagellar motor proteins PomB and MotY, which interact with the inner membrane.	3.63359e-35
NC_008536.1\|WP_011685816.1\|5207016_5207937_+\|phenylalanine-4-monooxygenase	gnl\|CDD\|237020	PRK11913, phhA, phenylalanine 4-monooxygenase; Reviewed.	4.95241e-114
NC_008536.1\|WP_041858016.1\|5189402_5191112_-\|arylsulfatase	gnl\|CDD\|293761	cd16142, ARS_like, uncharacterized arylsulfatase subfamily. Sulfatases catalyze the hydrolysis of sulfate esters from wide range of substrates, including steroids, carbohydrates and proteins. Sulfate esters may be formed from various alcohols and amines. The biological roles of sulfatase includes the cycling of sulfur in the environment, in the degradation of sulfated glycosaminoglycans and glycolipids in the lysosome, and in remodeling sulfated glycosaminoglycans in the extracellular space. The sulfatases are essential for human metabolism. At least eight human monogenic diseases are caused by the deficiency of individual sulfatases.	1.33385e-112
NC_008536.1\|WP_011685814.1\|5206079_5206640_+\|sigma-70-family-RNA-polymerase-sigma-factor	gnl\|CDD\|236608	PRK09652, PRK09652, RNA polymerase sigma factor RpoE; Provisional.	4.76923e-48
NC_008536.1\|WP_083783803.1\|5203389_5204289_+\|hypothetical-protein	gnl\|CDD\|379311	pfam13646, HEAT_2, HEAT repeats. This family includes multiple HEAT repeats.	8.19256e-07
NC_008536.1\|WP_011685798.1\|5186846_5187632_-\|DUF2950-family-protein	gnl\|CDD\|371539	pfam11453, DUF2950, Protein of unknown function (DUF2950). This is a bacterial family of uncharacterized proteins.	3.9972e-63
NC_008536.1\|WP_041858018.1\|5199453_5200635_-\|amidohydrolase-family-protein	gnl\|CDD\|236478	PRK09356, PRK09356, imidazolonepropionase; Validated.	1.49713e-98
NC_008536.1\|WP_083783802.1\|5193851_5195264_+\|DASS-family-sodium-coupled-anion-symporter	gnl\|CDD\|279307	pfam00939, Na_sulph_symp, Sodium:sulfate symporter transmembrane region. There are also some members in this family that do not match the Prosite motif, and belong to the subfamily SODIT1.	5.05786e-125
NC_008536.1\|WP_011685799.1\|5187642_5188773_-\|DUF3300-domain-containing-protein	gnl\|CDD\|378701	pfam11737, DUF3300, Protein of unknown function (DUF3300). This hypothetical bacterial gene product has a long hydrophobic segment and is thus likely to be a membrane protein.	2.5487e-91
NC_008536.1\|WP_011685796.1\|5179683_5183139_-\|carboxypeptidase-regulatory-like-domain-containing-protein	gnl\|CDD\|379297	pfam13620, CarboxypepD_reg, Carboxypeptidase regulatory-like domain.	3.58341e-17
NC_008536.1\|WP_011685797.1\|5184231_5186592_-\|tetratricopeptide-repeat-protein	gnl\|CDD\|276809	sd00006, TPR, Tetratricopeptide repeat. The Tetratricopeptide repeat (TPR) typically contains 34 amino acids and is found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi, plants, and humans. It is present in a variety of proteins including those involved in chaperone, cell-cycle, transcription, and protein transport complexes. The number of TPR motifs varies among proteins. Those containing 5-6 tandem repeats generate a right-handed helical structure with an amphipathic channel that is thought to accommodate an alpha-helix of a target protein. It has been proposed that TPR proteins preferentially interact with WD-40 repeat proteins, but in many instances several TPR-proteins seem to aggregate to multi-protein complexes.	3.20474e-17
NC_008536.1\|WP_011685808.1\|5200744_5201539_+\|rRNA-pseudouridine-synthase	gnl\|CDD\|224108	COG1187, RsuA, 16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases [Translation, ribosomal structure and biogenesis].	1.46272e-84

>NC_008536.1|WP_011685806.1|5196368_5199104_+|OmpA-family-protein
MKKLAAIGALGFLASGLFAQGLNTGGQTKDDWEEINFEFNSSILSDGYPSLLRLADLLSQHRDYKVKVTGHTDYVGSAAYNDKLALRRADAVKAFLVKYGVGDAQVTTSGDGKRSPIVDNKTKEGRFMNRRVDLAVTDGSGRLIKEGGIGDVINSLMSKLDDMAKKQQECCDQILKKLDKLDDILAQLKTLQGDNAKLQSQVDDLRNQHNALKDQVAGLPKPLTSSQTQDIAHTEALGAVDESQRRNKKFSVVSANIGPTYGAGRTGNFTFSGRGQFFSPFGGDGTRAVQAQGEYMYYPGRQEGQFDIGLVNRWGSIQAGAFGSFKYLNFKGNQQGGGLGQAAFLFDYVFSRGRIGIFGTQGFKNTAILNSVQLGPQSFLQTYAQIVNQYGGSALVGVWGNAYIEGNLAYLRNKNPNQSDAPGGSVRLVQPLNEHVAFTAEAGFNETLLNTNDSGRVVFGLQLGNYIHPKDYGKTKSPVPMDVPRVRYQLLTRRLGNSPPVANAGPDQVGVPGGTVTLDGSASYDPDNDPITYQWTQIGGNSVTLATPTAAKTTFTAVAGQTYIFKLTVTDTGGLSSSATTRVTATTPATATIVRFDATPNQISAGQSSTLTWIVQGATSVSINNGIGNVAASGSTTVSPTATTTYTLTAVGPNGNVTANAIVTVGAGGTTSAQIIRFEGNPLSIQPGQQSTLSWTTTGATQVSISGVGAVTPNGSTTVTPTQTTTYTLSATGSDGKTVTAPITITVASGTVPQVVVFVATPQNIDAGSSTKLCWQVTGATSISIQPGVGSNLNANDCATVSPTATTTYTLTATNATGQIQANATVNVGTVRITSFTADPVTSTAAGSPVTLSWTTENATSVVLIGSEIGPQTLPANGTFVIHPITNSTYTLTAYGNGGQTVSATISVFVR
>NC_008536.1|WP_083783802.1|5193851_5195264_+|DASS-family-sodium-coupled-anion-symporter
MAEKIEHSWWRWAVVIVPGVVLYFNPLPGMNAGQEHLFAFFVATIIALVAQPVPMGVSVLLAMTLVVVTGTLTAAKVLSGFGNVTVWLVFTAFLFSRAVTQTGFGMRVGYLFIERFGKTPLRLGYALAGADLVLAPFIPSDTARGGGVVFPVTRSVAKAFGSEPGATARKMGSFLMLVSFHTTYTASAMFLTGMAANPLIAEFAYKIGHVELTWGRWLSGSILPGMLTLAFVPWLLFRLARPEIQDTTAAREMARKELARRGPMGREEKWLVAIMGAVMAGWVTSPWHGLPNTFVALSGLCALLLARVIAWEDLLAEHRAWDALIWFAPLVMMADAMNENGAIKILSGGLFGLVHGWPWLMVLLLLVTAYCYVHYGFASMTAQVTALYPGFLAAALAGGVPPMMAALPLAYFSSLNAAMTHYGTGSAPVFFGAGYVRQGEWWRLGFLISVVNLVIWLGIGSLWWKLVGIW
>NC_008536.1|WP_011685803.1|5192234_5193689_+|carboxypeptidase-regulatory-like-domain-containing-protein
MLFGALCLILAAQDAGPVAGLVTSSLGHKGIGGVAVTAGALHTTTDSSGAFGLAGLPPGEHRFTFEAPGFFRHETRLRLDAGITAAPLNVELTPHSSISGRVVDAEGKALAGVQVEITQAIRGTGSTWNVWGAVTDKEGRYRAIGLGPGTYLAMARPDRDTSEEEKHAAVRTYYPSAPDRSQAGRLILRGGTDVAADIRVKTVPVYSIRGMIYDDEGRPANGLVSLESTEVLEGPTAKANMRDGAFEFPKVPAGDWRVIAEAEVAGRTLRGATATVVNRHDVENIAIRLAAPFALAVIVEPSGAPTIELYPVDAPRSQAAFAKANGDGKLEFPAVYPGRYSVNVFGTPKEHYLDAVMVGEQDVLGRERVFAEGMAPLRVVFKPNAAGVRGAVENCGGASVLLLPQDEGLWSYPFIQQRSCDRTGHFTIGGLRPGSYYAVAVDRIDGTGLDDLGTLRRLASMAERIQVESGRVGYVELKVQRWPE
>NC_008536.1|WP_011685802.1|5191227_5192223_+|acetamidase
MRFLLIPFLALAAYGADIQLKATPATVAWGYYWSAAKPVLRIKSGDTVEIQTMLTNSPDRLATAGVKSEEIEPELKAIYAEVKDKGPGGHILTGPIFVEGAEPGDTLEVRIVGIKYSIPYAYNSFSPRSGVLTPEDFAKGSMKIIPLDTKRNVAKFSDKIEIPLRPFFGSMGVAPAEAAGRVSSAPPGTHAGNLDNKDLVAGTTLFIPVHTAGALFEVGDGHAGQGNGEVDITALETSLVGTFQFVVRKDLHLKAPRGETPTHYIAMGLNPDLTEALKMAVREAIDFLVTEKHLSREDAYMLCSVGVDFNVTQAVDGTKGVHAMIPKSIFK
>NC_008536.1|WP_041858016.1|5189402_5191112_-|arylsulfatase
MLIPSQRRFMMLALAAFGIAGSAFAQTQKPNILFIMGDDIGWMQPSIYHRGLMVGETPNIDRIGNEGAIFMDYVAMQSCTSGRNAFFTGMYPLRTGMIPPQLPGSPSYLRPGTPALAVFLHDLGYTTGEFGKNHLGDHTEALPTAHGFQEYWGYLYHLDAMQGVSFPDINSTPTQQVIAPPCKNTPIPGLSEVPGAVDPKTTTCLTPPRPVLWCHSSDGTEKNQTCKDQGPLTLDRSRTVDEEISAKVVDFLDRNDPRKTNKPFFVWYNPARMHVTTMLSPKYEAMLGTRGGKDWGVNEAGMKQMDDNIGVVLAKLEQMGQLDNTIVVFTTDNGAETISFPDGGITPFKGQKGEAWEGGYRAPCVIRWPGHIKPGTVYKELFAALDWLPTFVEFAGGPKGDALKQQIEAGKYPGIVKTTLDGVNQSDYLQGKCDTSARDYFFYFSGATPSAVRYKNWKMYYTMSQPGPAGWIMPLIPFHFTLVQNIKRDPFEQAVGIDQKTAMGLGGALAGPITAFQYDWNMLPIGQQLWLKHLESYIKYPPLQEAASYNLSQVIEEVKKAQSVSHAGQ
>NC_008536.1|WP_011685800.1|5188802_5189387_-|hypothetical-protein
MPELPEAASKRVITWSIIWSILLMVVGCAAIASPIVSSIGAAFIIGWLVFIGGLVQFIHAVQSKGIGHLAWKLLVAAFYVMAGVYLVAHPLLELAGLTLVLAIIFCATGTADIVAWFSNRKIGGSVWMLVNGVVALFLGFTIWNRWPASSLWFLGTLVGISLFMAGMARLMMALAVRRLLHNPGSSPIHERRAA
>NC_008536.1|WP_011685799.1|5187642_5188773_-|DUF3300-domain-containing-protein
MMLKRSTQLLAVGLSLLISVPSRGYQNPESADSAGGAADAAPMSAAELQALVAPIALYPDALVAQILAAATFPDQVAVADYWVQQNHQLTGASLMQAVDKQSWDASVKALTQFPTVLDNLAKNLTWTSSLGEAYHDQASEVMAAVQALRAKAKAEGNLKSTPQMSVVQQTPQTIVIQPANPQVVYVPEYNPAVVYGYPYVTPGYTAAAVASGALAFGAGIALGSLGGGWNSWNCNWGGGAVVYNHNNFYGNSAWHGGYYNGGYHDGYGYHNAYNKTTVNNFHGTANRVNNLNREEDRNFNADRADSWSHDDSAFGRSNAFSGLGDRFGGAGGWASRANSFRGWGSMRAGGFSGGRFGGGGFHGFGGGGFHGGGFRR
>NC_008536.1|WP_011685798.1|5186846_5187632_-|DUF2950-family-protein
MSTYKLVTLALIMALASCGKADRTSSSTAMTAPSGRKTFASPSEAGAALLTAAQSGDRNTWLEIFGPDSAEVLFTGDAAQDQANLQAFVAAYTRMNRWGQIKAGGQTLYIGPDNYAFPIPLDKDSSGRWSFDTAAGKDEILARRIGRNELAAIAACDATAKGNSAKLASSKSGEHLPLLNGYYYRIAGKPGGSAGFTVLAFPAEYKNSGIMTFIVGKDGAVYQKDLGEKTGELAMATTRFNPSDGWTPALPHSGTASRATQ
>NC_008536.1|WP_011685797.1|5184231_5186592_-|tetratricopeptide-repeat-protein
MVRRGPLIVLAGAAACAAGAGLLWSHYTADIPSLSSPPALAGSGSCQGCHPKFYELWSTSHHGLAMQPVSADFVRRNLNLTQAPVRVGQATYAPEVDAKSAWLVERSPQGTRRYPLEQAMGGKNVYYFLTTLERGHMQVLPLSYDVNQRQWIDAAGNMVMHESGPSTAPADWRDRTLTFNTSCYGCHVSQLATNYDAASDSYRTQWREAGINCETCHGPSAEHVRLMRQAQREKRDRPPDDLKIVSVKNLTKVQRNDLCASCHAKLMAYTPGFKPGDRFFDYYNVAAFESDDFFPDGRDYRENYTFTSWSMSPCARTSDLDCLHCHTSSGRYRFKEDKLANNACMPCHEERVKNVAAHTHHKPDSAGSRCTSCHMPSTGYARMVRSDHSMRPPTPATTLAYKSPNACNACHADRDAGWADKQVRKWYKRDYQAPVLAQASLISSARNRYWTRLPAMLAALQRPGREPVFTASLIRLLGACPDRQIIPLFAVALEDPSPLVRSAAAEALSQNPSPLATVALLRAAKDNFRMVRIQAGVALSRFQTAGVEPSVREAVDRAVGEYVASLEARPDDFRRRLNLGVLRFDRGQYQQSIAEYQAAIRLRPDAAQPLVNESLAYNRLGENDRAEEALHQALRLDPRNSSAYLNLGLLMAEKRRIPDAEAALRGALDTDPDNAAAAFNLAVIVSGSRANEAIDLCRRAVKAAPGEPKYVYTLAFYLAQSGDTPGAAAALRRAISAGVANTQCYRALMRIYLQQGQPREALALSRQAAADPALPERDRASFLANR
>NC_008536.1|WP_011685796.1|5179683_5183139_-|carboxypeptidase-regulatory-like-domain-containing-protein
MPRYVAFFALLLLPAVASAQQVTGSITGTVTDPSGSAIAGATVRLVSEQTGAVRTVPADVEGNFVLTAVPAGMYTVGAEQTGFKKFLKTGLELSPGSNIAMGILKLEVGAVSESVTVRAEGAMVQAGTSERAGTVTSEEIQDLTVLNRDFTQFAELQPGIVANVTQEVQTFSGNTTFNAIGGRTTANNITIDGVTSSNTNQSNMNTTLSLDATASVEVKVANFQAEYGRNQGVTILAVSKGGSQKLHGALYYYFRNEDLNANNYFNNQNGTLRPEYRTSYAGGTFSGPLNLPHLKNRLFFLIGSEEIREMRPKSPQNVTVPTALERQGVFTQPVPGGKVVTVKDPTTGIAFPGNIIPANRMLPSMQSYLNLLPAPNYGNTAISGGNYNYVFQESLNVPKRDETGRLDFNASDKTQMYIRYGYWWEDQQGAAVSAGNASWGWLPDHYTPVTQTAIASGTHILNPSTVIQASLAYQRFVENGPPLNDSLIQAKSKTATGVNIPQFFPQNNPFNLVPAATFGGVTNAANPTYNARFPLRGVENTYTANLSASRVQGPHTIKTGLYAEHWAAMKGNNGTNFAGSMVFTQDGNNPLDTGYAYSNALLGVLDNYSEPSSRAGLYEVTTSVEWYAQDTWKLSRRVTMDAGVRFAFAQPWHSQQYQEAGWVPSAWNPANTVQLMQPVLVGSSRMGYDPISKATYPAVTIGAIVPEMTGNYNGIVYRAASKSYPQGLRNNSGIKTAPRLGIAWDPSGNGKTVIRTGGGVFYNMHEADNYPNGIEYTQPIQYNSTVYYTYLNDLLGAKGLTFPGTIQGFDVQNKTSVTYNFSFNVQRDIGMGTVLDVAYVGALSRHLQARVNLNSTALGTNYLAGSRDASNKNAVLPSQFLRPWLGYGDINYYANAYNSSYHSLQTKVNRRYRKNLMYGVVWTWSKTMDYADANATTLSTQINQKIWNYGEAGYDHTHILRVFWNYNVPKASALVNNKFVRGAFDGWQISGIYTAQSGVPLGISSSYSPSQDVTGSTDGGRVLMVADPVLAKSDQTFYQAFNVASVAPVPYAACEKANPDPICWGNAPKYSFRGPGINSWDTSLFKNFSLTERLRAQFRAEFYNVFNHTNFNGVDSAAKFNAAGAQTNLTFGQYSSAQFPRRLQLALRLMF
>NC_008536.1|WP_041858018.1|5199453_5200635_-|amidohydrolase-family-protein
MPRLGTGLNDLGIITDGAVLIRNGVIVEVGSSRRVENLASARHAVEINAAGRVVMPGFIDSHTHLAFPPAGVSAANQETAARAVRAATGQRLELRTRAYLEAMARHGTTTVEIKTGCGPDDACEAKLLRLLAAVRRDPLEVIASYLFRLPPAIEGGALLGAVEWAANDLLPKIRRRRSIDFADLAWNADPVMLPSFERFLAAAHKLGFACRIHADGPSPDSAVELALRHGVSGVDHLEYATEAHARQLARAGIVTTLLPGGAFHNDGKIPPARALIDAGAAIALGTNFNPTHSPMLNMQTSIALACWRLRMTLEEAISAATINSAYALRCADRTGSLELGKSADLVILNAPDYRDLSTCIGTNLVHLTMKRGKFIYKEGEVAPRPPEIITPPQ
>NC_008536.1|WP_011685808.1|5200744_5201539_+|rRNA-pseudouridine-synthase
MEKKRNRQEKITLKTLERVFSKAGAGSRTDARKWISGGKVRVNGKVVLNPDHWVDPDHDKVTLEGKPLKAATKSYILLYKPKGYLTTYRDPEGRPTVYALLGDVGKWLSPVGRLDLDTSGLLVLTNDNDFAERITNPEHKVPKTYQIKAATVLSDEQIERLRAGVELSDGPTRPAEVKRLRDGPKHTFLEMTITEGRNRQVRRMLEAVESKVSKLVRTAIGPVRIGELPIGKWRNLTADEVHELRGQAAKKASGPARDKNRNKY
>NC_008536.1|WP_011685809.1|5201775_5202696_-|hypothetical-protein
MKISRNLLCLALLGTAILVRAQAPAQQAPPQQPPAETPQVETQRPIKLPPAPPEVIDIRMPGEAGWSFGLTGWLPIGQPFVDKGHGVTFTTPSKLELVGTSKGAPGAEIGIAAGRHNSLKFSYFQSKQSGNTVAPNDLVVFTQAYNKGDILSTNSKLTNAKVSYEYLTWPFPVEARHFRLKTLWQAQYISMKSVFDAPVRSGTPNSAGNYTDYSTLGSKSYFTPSLGLGVQEYASRNFRLEANVSGFMWPHSFRLVDSDATIAYRIGHIELRAGAKAFIFRTSPKQDYFYRGTTGGAFVGVRWYSD
>NC_008536.1|WP_011685810.1|5202952_5203483_+|RNA-polymerase-sigma-factor
MREVREGEVGKLETLFDRHYQGLFRYFLYLTGNRAASEDLAQEVFFRILKYRHTYQPEAGFRAWLYQIGRNVYADYLGKQKPEVELAEDAGEIRGSEAPADRQVQKKQEALLLRRALASLPGEKREVLIMSRFLDLRYEEIASVLKCEVGTVKVRVYRAMRELSDRFFALSGERAS
>NC_008536.1|WP_083783803.1|5203389_5204289_+|hypothetical-protein
MRSGDGKGTGVPGNAGVERPLLRAKWRTSVMSCERIREQIPEVLAGRLDKGAREKLVEHLESCAGCRAEVAEMNAVWRGMENLKAESDDAPQAAAKARFHEVLAAYEAGMAAAQPGGSRVVKFPVRPVWQIAMAAGLLAAGIFAGRYLAGGGTGNTEMAQLKGQVEGLRQMVALSMLQGQSPSARMRGVTYSEQISQPDRQVRDALLQAVNHDSNVNVRLSAVDALQKFAADPELTRAMVDSIPAQDTPLVQIALIDMLVQLNARGATEDLARLAKNMQLDEMVRQRAAWAVHKMEAER
>NC_008536.1|WP_011685812.1|5204285_5205143_+|hypothetical-protein
MRYGATLAMAALPMVLCAQYSGHTWKLDEQETIRKTFDVGTSDRKLLVDNVHGYVHVTGYSGTQIQVTVDKHILADRAEATAEAKRDVKLDMSQQGSFVRLYEDGPFRTSNGDTNYRGEDYYGYRVVLNFDVQVPFDTELVLKTMNHGEIQVKKTTGDYDIHGLNGGIEMEDVAGSGSVNTLNGTVKVTYSKNPTKATQYKTLNGTVDVYFRDGLNADLKFKKLNGGIYTDFDVTAVPQSANGDSRDGKFLYRPNGRMSGRTGKGGPELSFETLNGSIRLHTKTL
>NC_008536.1|WP_011685813.1|5205157_5205973_+|hypothetical-protein
MKTYWALMGITLAVCSTGIAQEPGNERVVVPVRNSTHPRKVDVNLMGGSITVKSYNGKEVIVESTGSGSRSRREPEDKRADGMRRLDLPDRGISVEEQDNVVTVRMQNARRGSSVTIMTPADTSLTLHTMGGDIEVDGVKGEIDANSMNGKITLNNVSGSVLAHSMNGGMKVVMDSVDAGKPLSFTTMNGTIDVTLPADFKGNAKIRTDHGEVYSDFDFKLGGGAMTQKNDTSDGKFKVAMDRTITGTINGGGTEATFKTYNGTIYIRKRK
>NC_008536.1|WP_011685814.1|5206079_5206640_+|sigma-70-family-RNA-polymerase-sigma-factor
MVLECTDRELVEGCRRGEREAFRVLFETYKDKIYSIALRFSGDQALAMDIAQDTFLKLYSSIADFRGESQFSTWVYRLVVNSCLDHKRKSWRMIPLADELLAVMRAPGDALHAVIRTEMSERVQRAVEKLPEEQRIVVVLRYTEGLAYEQIAEVIGCSMGTVASRLNRAHRALERRLANLKGAAHV
>NC_008536.1|WP_011685815.1|5206632_5206950_+|hypothetical-protein
MSDWLEEQLSQHLNPVKAPEKLGVRLGFARATRHQVPRMAVALAAAIVMMAGGLAANREARNGEAVQFAAAEQGTIPVRLGHQPSGTEKSANLTADAGCGACHSL
>NC_008536.1|WP_011685816.1|5207016_5207937_+|phenylalanine-4-monooxygenase
MASTLAAPGLTTGRAPFVEEARTRGELYITQPYELYSKENHEAWQKLFKRIHTRWERYANDHFLRGVEALELPHDRVPRLTDVNRRLQPLTGFQAKPVSGYVPGFLFFDCLRRREFPTTITIRPADRMDYLPEPDIFHDVAGHVPMHTERQFADTLVRFGDCAVTAARITAEVKDPAKRVRRLTSIMRAMSRFFWFTVEFGLMRGTKGTVAYGSGLLSSYGELEHAIESDEVQRYPIQLEWVINQVAEIDHYQPILFVVDSFEHLFDLVDEFEKWMIEGKLYNVAPGLPEIAEGDLQSFLDAAGTR

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Crispr_ID: NC_008536_8

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_008536_8

5345204-5345290

Orphan

Consensus_repeat	Method
CGTGACCGGAGTCTGGTCACGGA	CRISPRCasFinder

1 spacers

The CRISPR arrays of NC_008536_8

>merge|NC_008536|8|5345204-5345290|CRISPRCasFinder
CGTGACCGGAGTCTGGTCACGGAATTTTCATCATTCCCATGTTTTCAACCACTTCCCTGATTCTCGTGACCAGAGTCTGGTCACGGA

>NC_008536|8|8|5345204-5345290|CRISPRCasFinder
CGTGACCGGAGTCTGGTCACGGA	ATTTTCATCATTCCCATGTTTTCAACCACTTCCCTGATTCT
CGTGACCAGAGTCTGGTCACGGA

Protein	Signature genes	Signature genes Name	Protein_function
NC_008536.1\|WP_011685935.1\|5342036_5342228_-\|Flp-family-type-IVb-pilin	unknown	unknown	gnl\|CDD\|226366
NC_008536.1\|WP_049873164.1\|5352248_5354126_-\|S9-family-peptidase	unknown	unknown	gnl\|CDD\|224423
NC_008536.1\|WP_041858041.1\|5343795_5344578_-\|amidohydrolase-family-protein	unknown	unknown	gnl\|CDD\|238624
NC_008536.1\|WP_011685940.1\|5347362_5348004_+\|riboflavin-synthase	unknown	unknown	gnl\|CDD\|236455
NC_008536.1\|WP_011685931.1\|5338794_5338980_-\|hypothetical-protein	unknown	unknown	unknown
NC_008536.1\|WP_011685933.1\|5339430_5340930_-\|tannase/feruloyl-esterase-family-alpha/beta-hydrolase	unknown	unknown	gnl\|CDD\|284851
NC_008536.1\|WP_011685944.1\|5356090_5357011_-\|VWA-domain-containing-protein	unknown	unknown	gnl\|CDD\|274577
NC_008536.1\|WP_011685938.1\|5345325_5346276_+\|signal-recognition-particle-docking-protein-FtsY	unknown	unknown	gnl\|CDD\|236686
NC_008536.1\|WP_011685930.1\|5338011_5338791_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|372305
NC_008536.1\|WP_011685942.1\|5355214_5355529_+\|hypothetical-protein	unknown	unknown	unknown
NC_008536.1\|WP_041858042.1\|5344577_5345150_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|238624
NC_008536.1\|WP_011685937.1\|5342504_5343704_-\|Flp-pilus-assembly-protein-ATPase-CpaE-like-protein	unknown	unknown	gnl\|CDD\|349765
NC_008536.1\|WP_011685941.1\|5348141_5352053_-\|carboxypeptidase-regulatory-like-domain-containing-protein	unknown	unknown	gnl\|CDD\|379297
NC_008536.1\|WP_049873165.1\|5354156_5354843_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|225921
NC_008536.1\|WP_011685934.1\|5341028_5341982_+\|TIGR03435-family-protein	unknown	unknown	gnl\|CDD\|132476
NC_008536.1\|WP_157675418.1\|5342244_5342421_-\|Flp-family-type-IVb-pilin	unknown	unknown	gnl\|CDD\|226366
NC_008536.1\|WP_011685939.1\|5346272_5347382_+\|bifunctional-diaminohydroxyphosphoribosylaminopyrimidine-deaminase/5-amino-6-(5-phosphoribosylamino)uracil-reductase-RibD	unknown	unknown	gnl\|CDD\|273015
NC_008536.1\|WP_011685932.1\|5338979_5339396_-\|hypothetical-protein	unknown	unknown	unknown
NC_008536.1\|WP_157675419.1\|5355584_5355737_+\|hypothetical-protein	unknown	unknown	unknown
NC_008536.1\|WP_011685945.1\|5357064_5357526_-\|membrane-protein	unknown	unknown	gnl\|CDD\|226432

Protein	Function_ID	Function_description	E-value
NC_008536.1\|WP_011685935.1\|5342036_5342228_-\|Flp-family-type-IVb-pilin	gnl\|CDD\|226366	COG3847, Flp, Flp pilus assembly protein, pilin Flp [Intracellular trafficking and secretion].	3.17578e-06
NC_008536.1\|WP_049873164.1\|5352248_5354126_-\|S9-family-peptidase	gnl\|CDD\|224423	COG1506, DAP2, Dipeptidyl aminopeptidases/acylaminoacyl-peptidases [Amino acid transport and metabolism].	4.41457e-56
NC_008536.1\|WP_041858041.1\|5343795_5344578_-\|amidohydrolase-family-protein	gnl\|CDD\|238624	cd01299, Met_dep_hydrolase_A, Metallo-dependent hydrolases, subgroup A is part of the superfamily of metallo-dependent hydrolases, a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the members have a conserved metal binding site, involving four histidines and one aspartic acid residue. In the common reaction mechanism, the metal ion (or ions) deprotonate a water molecule for a nucleophilic attack on the substrate. The function of this subgroup is unknown.	1.90012e-24
NC_008536.1\|WP_011685940.1\|5347362_5348004_+\|riboflavin-synthase	gnl\|CDD\|236455	PRK09289, PRK09289, riboflavin synthase.	1.69759e-106
NC_008536.1\|WP_011685933.1\|5339430_5340930_-\|tannase/feruloyl-esterase-family-alpha/beta-hydrolase	gnl\|CDD\|284851	pfam07519, Tannase, Tannase and feruloyl esterase. This family includes fungal tannase and feruloyl esterase. It also includes several bacterial homologs of unknown function.	7.8494e-127
NC_008536.1\|WP_011685944.1\|5356090_5357011_-\|VWA-domain-containing-protein	gnl\|CDD\|274577	TIGR03436, acidobact_VWFA, VWFA-related Acidobacterial domain. Members of this family are bacterial domains that include a region related to the von Willebrand factor type A (VWFA) domain (pfam00092). These domains are restricted to, and have undergone a large paralogous family expansion in, the Acidobacteria, including Solibacter usitatus and Acidobacterium capsulatum ATCC 51196.	3.21883e-106
NC_008536.1\|WP_011685938.1\|5345325_5346276_+\|signal-recognition-particle-docking-protein-FtsY	gnl\|CDD\|236686	PRK10416, PRK10416, signal recognition particle-docking protein FtsY; Provisional.	8.52072e-172
NC_008536.1\|WP_011685930.1\|5338011_5338791_+\|hypothetical-protein	gnl\|CDD\|372305	pfam12773, DZR, Double zinc ribbon. This family consists of a pair of zinc ribbon domains.	0.000324385
NC_008536.1\|WP_041858042.1\|5344577_5345150_-\|hypothetical-protein	gnl\|CDD\|238624	cd01299, Met_dep_hydrolase_A, Metallo-dependent hydrolases, subgroup A is part of the superfamily of metallo-dependent hydrolases, a large group of proteins that show conservation in their 3-dimensional fold (TIM barrel) and in details of their active site. The vast majority of the members have a conserved metal binding site, involving four histidines and one aspartic acid residue. In the common reaction mechanism, the metal ion (or ions) deprotonate a water molecule for a nucleophilic attack on the substrate. The function of this subgroup is unknown.	5.28315e-12
NC_008536.1\|WP_011685937.1\|5342504_5343704_-\|Flp-pilus-assembly-protein-ATPase-CpaE-like-protein	gnl\|CDD\|349765	cd03111, CpaE-like, pilus assembly ATPase CpaE. This protein family consists of proteins similar to the cpaE protein of the Caulobacter pilus assembly and the orf4 protein of Actinobacillus pilus formation gene cluster. The function of these proteins are unkown. The Caulobacter pilus assembly contains 7 genes: pilA, cpaA, cpaB, cpaC, cpaD, cpaE and cpaF. These genes are clustered together on chromosome.	2.98924e-30
NC_008536.1\|WP_011685941.1\|5348141_5352053_-\|carboxypeptidase-regulatory-like-domain-containing-protein	gnl\|CDD\|379297	pfam13620, CarboxypepD_reg, Carboxypeptidase regulatory-like domain.	1.83624e-19
NC_008536.1\|WP_049873165.1\|5354156_5354843_-\|hypothetical-protein	gnl\|CDD\|225921	COG3386, COG3386, Gluconolactonase [Carbohydrate transport and metabolism].	0.00196204
NC_008536.1\|WP_011685934.1\|5341028_5341982_+\|TIGR03435-family-protein	gnl\|CDD\|132476	TIGR03435, Soli_TIGR03435, soil-associated protein, TIGR03435 family. Bacterial reference strains encoding members of this protein family are all isolated from soil. These include 39 members from Solibacter usitatus Ellin6076, 27 from Acidobacterium sp. MP5ACTX8 (both Acidobacteria), and four from Pedosphaera parvula Ellin514 (Verrucomicrobia). The family is well-diversified, with few pairs showing greater than 50 % pairwise identity. A few members are fused to Peptidase_M56 domains (see pfam05569), to Sigma70_r2 domains (see pfam04542), or have a duplication of this domain.	3.32335e-110
NC_008536.1\|WP_157675418.1\|5342244_5342421_-\|Flp-family-type-IVb-pilin	gnl\|CDD\|226366	COG3847, Flp, Flp pilus assembly protein, pilin Flp [Intracellular trafficking and secretion].	3.85651e-09
NC_008536.1\|WP_011685939.1\|5346272_5347382_+\|bifunctional-diaminohydroxyphosphoribosylaminopyrimidine-deaminase/5-amino-6-(5-phosphoribosylamino)uracil-reductase-RibD	gnl\|CDD\|273015	TIGR00326, eubact_ribD, riboflavin biosynthesis protein RibD. This model describes the ribD protein as found in Escherichia coli. The N-terminal domain includes the conserved zinc-binding site region captured in the model dCMP_cyt_deam and shared by proteins such as cytosine deaminase, mammalian apolipoprotein B mRNA editing protein, blasticidin-S deaminase, and Bacillus subtilis competence protein comEB. The C-terminal domain is homologous to the full length of yeast HTP reductase, a protein required for riboflavin biosynthesis. A number of archaeal proteins believed related to riboflavin biosynthesis contain only this C-terminal domain and are not found as full-length matches to this model. [Biosynthesis of cofactors, prosthetic groups, and carriers, Riboflavin, FMN, and FAD].	1.66501e-107
NC_008536.1\|WP_011685945.1\|5357064_5357526_-\|membrane-protein	gnl\|CDD\|226432	COG3918, COG3918, Predicted membrane protein [Function unknown].	1.2335e-44

>NC_008536.1|WP_041858042.1|5344577_5345150_-|hypothetical-protein
MPFWWRYNLALAVFAQVAFAQADQPLALTNLTVIDATGRAPQPNMTVVISGGRIVSISPAGAAKPGPGDGVEDCTGKYLIPGLWDMHVHVSNAGDLEARLFAANGVTTIRDMGGNLVMLDWLRRRIEQAGFAGPRILRPGPFVDGLKPGLPDRLVVANAAEGRDAVHYLKQLGVDFIKVHTGVPRPAYLG
>NC_008536.1|WP_041858041.1|5343795_5344578_-|amidohydrolase-family-protein
MAEAMQEGMAVAGHVPLSVTPVEASNAGQRLIEHMSVLAEKRANELLNGGMPMARMSETVAAEMPELFRTLARNGTWMDPTFVAMRQGAYRYQIASQPDERRKYVAASIRKGWDRARPVSQEDAKTQKIRAELFETQLQWAAAMKEAGVRFVAGTDTGIRDTFPGFSLHEELVWLCKAGFSTMEALQAATRNPAIVMGHGSSLGTVEAGKDADLLILDANPLDDISNTTKIHGVMLRGRLFTREALDGLLSEAEKLAALR
>NC_008536.1|WP_011685937.1|5342504_5343704_-|Flp-pilus-assembly-protein-ATPase-CpaE-like-protein
MPPQPTRGRTIVWKPLVVCPQPDFHRRMLAALEVLAIDHSCALTQYPPAGAIAGLAERNGCNICFLDAATDCELAQTLISELAPGLPVVALHPSNDADLILRCLRRGACEFVADPTSDTLRCVFERLARTRSDAAHPAAGSVYCVVPGKPGCGASTLAAHLAIQLRGSGVEPVLLVDGDHLTASITFLLKLKPEFHLEDVLRDWSRMDDDLWARLTVPAFGVDVLAAPEDPTTRTPVSRQAAGELCNFWRERYAAVVLDLPDMRAAADCGFAALADIVLLVTTNELAALQATGRALRYLDSAAGDRSRLRLILNRYTPATGLKREDVKTALSLEPFAILCNDYEVIQTALLDGRPAPAGSRFSGSVQALCRQLEHKSQPHRKHGFSLGSLLRRKSSVSR
>NC_008536.1|WP_157675418.1|5342244_5342421_-|Flp-family-type-IVb-pilin
MKTFCKRFWQDTQGQDLVEYALAAGMVAVAAVAVMPTLSTTVSTVFTKIGSIVENTVK
>NC_008536.1|WP_011685935.1|5342036_5342228_-|Flp-family-type-IVb-pilin
MKTLKDYVWRLRIWKDSGGQDLVEYALAAGLVAVAAVAAMPALSGTVSTVFTKIASIVNNNVK
>NC_008536.1|WP_011685934.1|5341028_5341982_+|TIGR03435-family-protein
MRRGICCAGVLALTAWTASAQTGDVPTTFEVASVKPAASMVGGMIRVRMAGGPGQPDPGQINYSNVTLKNVLMTAYNVKGYQISGPSWLESERFDIVAKVPKGATKEQFQLMLQNLLAERFKLKLHRESKELPIYALVVAKNGLKMKETPKDDPAAPAAGTPPASPDAGFGGGEPRIRMGKDGMPQMPPGGPGRGGMMMMMGNGGKARMQANKQKVTQIAEMLGNQLGRPVVDQTGLTADYDFSLEFSADDTMRGPGMMAPPAPSPDGGGAGVSASEGGGPSLMAALQEQLGLKLEPKKGPIDLLVIDNLEKVPTEN
>NC_008536.1|WP_011685933.1|5339430_5340930_-|tannase/feruloyl-esterase-family-alpha/beta-hydrolase
MRILLAAFATGLALSAQQKPVTGCPDLRSLTNHEVSIAVAAPVAETPNAPPHCRVFGQVLPQVGFEVRMPAEWNGRFVMIGNGGFAGEPTDSPGRVSQYGRYMKRGYAVAATDTGHSGITDTGATFAADRQKLLDYAFRSLHVTAEAAKMLLRAYYGAAPAKSYFEGCSTGGRQGLILAQRFPNDFDGITVGAPVLNFTGTMIRFVQVAKALKAAPIATNKMPTLAARIYEGCDAKDGVKDGVIDDPRRCDFRPARDLPKCEAGADRPDCFTDPQIHALEEIYAELKSQGKRIFPAWPVGPEAVGQNGHSGWDSWSVHDGGPSTGVFFAEGFFRYMAPPKPDPAYDIFSFNIDKDVAKLDSIHQILDATDTDLSAFQKHGGKILMYFGWADPALNPMMGVEYYEAVAERMGPKTGDFFRLFMVPGMLHCGDGPGPGVFDTTGPLSQWVEKGTAPDSIKAMKVVEGKAVRSRPLCVYPAAAKYNGSGSTDDASNFTCVKP
>NC_008536.1|WP_011685932.1|5338979_5339396_-|hypothetical-protein
MAKEKEQKQPMPPLGAWVPAVALGWLIPGGGHFLLKRTGRGALLLVSITTMFLFGLMMQGAMFQPQSGDLLTTLINTGGFIGNLCSGILYLLSVWFGYNQPDMAGHVHDYGTKFLVTAGLLNVLAMVDVYEIAAGRKE
>NC_008536.1|WP_011685931.1|5338794_5338980_-|hypothetical-protein
MPKMNLSHFEAAFLFALFTSVVLGVVTKRNDRDRLHYGVYTFACFMLALFGIGWLMYLGHG
>NC_008536.1|WP_011685930.1|5338011_5338791_+|hypothetical-protein
MAFCTSCGATVQGAFCPQCGTAVSSSASQSVPPQAAYAQAAAPAAVPGKRRTSPWVWILVGVLGLFLLCVIGLISAGIFVARNPGMVMGKLITAANPNAEVLSTDMGSKTMRLRDKRTGKEITVSFDDVKNGRIRFSATGDDGQEATVEIGGGAGQMPRWVPAYPGAKAQGNMTAKGEGADGMGEGGMISFSTADPASKVIDFYTSKCKEMGMNVDVSAVTTDGGTLVATDESGNRAIHVMVGGHGDNTTFALTFGRKR
>NC_008536.1|WP_011685938.1|5345325_5346276_+|signal-recognition-particle-docking-protein-FtsY
MIQTLFGSVEQEPSLLEKLKSGVQKTRAGLVTALEDALQGKKEIDADLLDELEFTLISADIGVATTSEILESIRQRVERHQLADAGELKGLIRERLLEILQASERAPARVAEPPAVVLVVGVNGAGKTTTIGKLAHRFKNEQRSVLLCAADTFRAAAIEQLEIWGERTGTQVIRQKPGSDPSAVLFDAVTAAKSRKVDYVIVDTAGRLQTKEHLMLELEKMNRTARKVIPDAPHEVLLVLDATTGQNGLEQARKFTGSSGVTGIVLTKLDGTAKGGIVVAIARELNLPIRYIGVGEKIEDLLPFDGEKFIESLFEK
>NC_008536.1|WP_011685939.1|5346272_5347382_+|bifunctional-diaminohydroxyphosphoribosylaminopyrimidine-deaminase/5-amino-6-(5-phosphoribosylamino)uracil-reductase-RibD
MSSSYMREALDLARKGRSLASPNPLVGAVIVRDGKVVGRGFHTYAGLHHAEIIALAQAGEQARGAEIYLNLEPCSHQGRTPPCVDALIRAGIARVVAPLSDPNPLVAGQGFARLREAGIEVVMADEFAAEAGKLNEPFLHFMLTGRPLVTLKTAITLDGKISAPDDNRGWITSERARAHVQELRHDHDAILTGIGTVLADDCLLSDRTGHPRCRPLLRIVMDSQLRLPLDSKMARSANGDVLAITTSAASSERRKMLESRGIQVLVFDGPGGRADLRSIVEWLGRHRYLSLMIEAGSKLNWSALEGNVVDRVFFYYGPKILGGLEALPLAGGIGRRRRQDAIQLHNLSIHQIPPDEFAVEGYIDVHRDY
>NC_008536.1|WP_011685940.1|5347362_5348004_+|riboflavin-synthase
MFTGIIEELGAIEAVQTRAAGARLTIRCSAVLSDAVEGASIAVNGVCLTAVDLRPASFSADLAPETLQRSNLGDLRAGSRVNLERPLSPTGRLNGHIVQGHVDGTGEFLSLEALGDDNWWLRIRVPAELDPYLVFKGSIAIDGISLTIASLESDVLAVTIIPHTFRGTTLGSYRPGARVNLECDVLAKHVEKLLKKLDLKEALTVDKLRAQGY
>NC_008536.1|WP_011685941.1|5348141_5352053_-|carboxypeptidase-regulatory-like-domain-containing-protein
MKVRLCAPVLPVFLLMLAAALHCAFAQGGVTTALTGTVFDSSGAIVPGANIVAKNKATASSSTAVSGADGLFTIPALEPGNYDVTVAIKGFATAVLEDIRLNAGAPSNIKAVLTPGGVAETVVVESAGEILKTTQTSVTTTLTQQQLTSLPLPGRAAFDLITFLPGVTTADGTSRGAMVNGLPTSTVNITLDGMNIQDNYAKTWDGMFTRVSPRLDAVEEVTIGTAAQGADMAGQGGVQIKMVTRSGTNEYHGSVYYYLRRDWMNSNTWFNLHRNVDINGNPTSTPVSKQFQPGGRLGGPVRIPKLFNGRDKLFFFVNYEWVSSPGTSTSTRTIMSPLSEQGIFQYAGGANVDLMAMAARNGQVARIDPLVAKMLGDVRKSTSITGVVNSTTDPLTQSFVWQQPTTSKTTFPTVRVDYNVTAKHRLTGSITQNHLISDPDTTNSVQAVYPGFPVHGLQDSTRYTGQGAWRSTLSSRIVNEFRFGKTGGATQFSPDLTSDMFAGAGLGAANGYAISWSGFKSIANPYPASANSSREGKTMVFEDSLNWVKGRHLLSMGVSYTKAEVWLYNQTKAPVLTLGMTSSGDPADSMFTTANFPGASSTDITNARNLYAVLTGRVSAITRNARIQPDGSTYKILGASDQYGTLPEWGSFINDSWHAKPNVTVNAGLRYDVQRPFYAQNNSYSTATLDDIFGVTGVGSGFEPGSVVNNLGNLFKPGALQGAPTTFKMLTKNSNAYHTDWGGFAPSLGAAWTVGADSGFLHAVLGSKGNSVLRGGASLAYQRGGMSDFTGVFGSNPGISIDASRNQTNGNLGAVPVLLSSSDLGPPAINLTRAYPMAVPSASSSVYVFDPNIKTPSAFSYNLSWQRQLARNLTIEGRFIHTNSFNTWTAGGQLPYLDYNEINILENGFLPEFKLAQANLQANIAAGKGSTFAYTGVAGTSPLPIFLAYLNGAKTPADATKYTGTGWTNTTVVQSMYPLNPNPYTAASNIWANSAYRTNGLAAGYPSNFWVANPDINHGYVVTNGPKTSYNGVQVSLNRRFSDGLLFELNYTYGRGYMDQFYGFHKPYVNTEMNYTNINTNQNGNATGNVRHVFVGNWMYQLPFGKNKHFLAGAGGLLDRVVGGWSFQGVGRLQSGRMLDFGNVRLNGMTPDDVRSAFKMRQVTDPQNPYRTLIYMLPQDIIDNTIKAFSVGATGYTNGAPTGRYFAPANSPSCIESVNGFGDCGLRSLIVTGPKVLRFDFNLIKQIRVTERLVLEGQAQVFNVFNNVNFNPVNYVGSVSDSYQVTGAVDQSRTMQLAFRISF
>NC_008536.1|WP_049873164.1|5352248_5354126_-|S9-family-peptidase
MFEYYATAQLAVVDSVSGAASPIGKPAMLESARMSPDSKFVIVSYIHKPFSYSYPARLFPTEIETWDRTGKLLRKEASIPLGGNGRGAGAANAAADEENPVAAGPRGLSWLITEPSTLIWFEGNGGAGRGGRARGGTPASASAAPQPIHEKLMALKAPFDGTAQVMYEADQRLEGFALTDDLHTAIIGAGGGGGRGGAAGRGAARAQTAYLIDFAKPKEAPKPLWTSGPSRYNNPGSPVEKPLPTGGRVVVRDGDNIFLQGNGASPNGDHPFLSRYNLVTQETKKLFQCDDTHYETFDGLLDSHGDKFLTRRESPTEPPNYYVRTSSGQSTAITHFPDPQPIMRKVHQELVTYKRPDGVDMSFTLYLPPDYTPGKPLPTILWAYPYEYETADVASETASNGSRMRFTEIGGYSDIFFALDGYAVLHNASMPIVGPRATVNDHFLEQLLMDAKAAIDKAVEMGVTDRNRVGVGGHSYGAYMTDSLLANSDLFKAGIAESGAPNRTLTPFGFQNERRTLWDDPDLYIRMSPFMAANKIKTPLLLIHGEADDNNGTFPIQSERMYEAVRGNGGTVRLVFLPSEAHGYRAKETIEHVNWEKLRWFDKWVKDPPPANMRGTTTNNENKLQ
>NC_008536.1|WP_049873165.1|5354156_5354843_-|hypothetical-protein
MTPPLRLLCILTSANLLLFAADTYQKPPKAVEDILNSPTTPTLLMSPNRAYALQGSPVRYPPIAELSEPMLRLAGIRINPRTNGLHNATFQSNLMLRKIPEGTEIKIALPANPKLGIGPWSADGTRFVFTNSTSSGIEVWIGEAATGRTHRVPNLHLNEVLGGGRGGPAAGRGGAGGGGGGLQWAPDGKSLLVFAVPANRGAAPAAPIVPAGPHISESLGGGKGAPTY
>NC_008536.1|WP_011685942.1|5355214_5355529_+|hypothetical-protein
MALTKSFRETVYHRAQRDGAFRKTLLMEAVNAYLSGDQLTGKAILRDVINATIGFEQLAADLQKPSKSLHRMLGPNGNPNTVNFFAILQVLQKRIGVRLTVRAA
>NC_008536.1|WP_157675419.1|5355584_5355737_+|hypothetical-protein
MRDAFAVIPNEPVAAFGNRLLLVFTLEFVIHGSISERCLHGIDNGFQQSY
>NC_008536.1|WP_011685944.1|5356090_5357011_-|VWA-domain-containing-protein
MQISRRTFLLGYAIPLAAQEPPTFSAGVDVVTLMATVRDRDGRIARDLTRDDFVLHDEGKRQSITYFSKESDLPLTIGLLVDTSRSQRGVLEPERKASFTFLDQVLRDGKDFACVVAFDTDVRLLQPFTSSHAELAGALERLRIPNQTATVIFGAIRDTAENQMRPRKGRKAFIILSDGVSVRDTTTIGTAIEYAQRADTIIYSILFADHRGLRRPARKAAMGMRALQGKKAMQRLAQETGGEFFEVSASNPITRTYAAIEETLRNQYSIGYTPQAPGKSGQYRKIKLTTRQKGLTAQTRDGYYAK
>NC_008536.1|WP_011685945.1|5357064_5357526_-|membrane-protein
MSICVLFAFLIGVVAGLRALTAPTAVSWAAALRWLHLEGTPLAFMGYAATPYIFTVLAIGELISDQLPNTPSRKAPPGFIARIVTGGLCGAAFGFQRDEVVPCVIAGVLGAVAGTLGGYEARVRLARAVGRDLPIALLEDAIAIGGAFFLVSR

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Crispr_ID: NC_008536_9

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_008536_9

5988033-5988119

Orphan

Consensus_repeat	Method
TCCGTGACCAGACTCTGGTCACG	CRISPRCasFinder

1 spacers

The CRISPR arrays of NC_008536_9

>merge|NC_008536|9|5988033-5988119|CRISPRCasFinder
TCCGTGACCAGACTCTGGTCACGAGAAAAATGTAAGTGACTGAAAACAGGAATAAATGCAAAAATCCGTGACCAGAGTCTGGTCACG

>NC_008536|9|9|5988033-5988119|CRISPRCasFinder
TCCGTGACCAGACTCTGGTCACG	AGAAAAATGTAAGTGACTGAAAACAGGAATAAATGCAAAAA
TCCGTGACCAGAGTCTGGTCACG

Protein	Signature genes	Signature genes Name	Protein_function
NC_008536.1\|WP_011686433.1\|5973976_5975380_+\|aminopeptidase-P-family-protein	unknown	unknown	gnl\|CDD\|223085
NC_008536.1\|WP_011686437.1\|5979207_5980608_+\|peptidase-C45	unknown	unknown	gnl\|CDD\|368190
NC_008536.1\|WP_083783834.1\|5978160_5979183_-\|selenide,-water-dikinase-SelD	unknown	unknown	gnl\|CDD\|273100
NC_008536.1\|WP_011686440.1\|5985973_5986933_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|276809
NC_008536.1\|WP_011686435.1\|5977459_5978164_-\|orotidine-5'-phosphate-decarboxylase	unknown	unknown	gnl\|CDD\|234695
NC_008536.1\|WP_011686434.1\|5975449_5977429_-\|M13-family-metallopeptidase	unknown	unknown	gnl\|CDD\|341056
NC_008536.1\|WP_011686448.1\|5997984_5999169_-\|6-phosphofructokinase	unknown	unknown	gnl\|CDD\|274155
NC_008536.1\|WP_011684349.1\|5988851_5989784_-\|IS3-family-transposase	unknown	unknown	gnl\|CDD\|222853
NC_008536.1\|WP_063720758.1\|5980608_5983905_-\|TonB-dependent-receptor	unknown	unknown	gnl\|CDD\|379297
NC_008536.1\|WP_011686446.1\|5992756_5996746_-\|carboxypeptidase-regulatory-like-domain-containing-protein	unknown	unknown	gnl\|CDD\|379297
NC_008536.1\|WP_011683270.1\|5989780_5990137_-\|transposase	unknown	unknown	gnl\|CDD\|366690
NC_008536.1\|WP_041859770.1\|5999848_6000952_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|226749
NC_008536.1\|WP_049873200.1\|5987032_5987431_+\|hypothetical-protein	unknown	unknown	unknown
NC_008536.1\|WP_011686439.1\|5984118_5985882_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|223679
NC_008536.1\|WP_011686449.1\|5999311_5999653_-\|response-regulator	unknown	unknown	gnl\|CDD\|236838
NC_008536.1\|WP_157675923.1\|6001093_6001618_+\|sigma-70-family-RNA-polymerase-sigma-factor	unknown	unknown	gnl\|CDD\|274357
NC_008536.1\|WP_011686445.1\|5990949_5992698_-\|tetratricopeptide-repeat-protein	unknown	unknown	gnl\|CDD\|131573
NC_008536.1\|WP_011686444.1\|5990218_5990944_-\|TIGR03435-family-protein	unknown	unknown	gnl\|CDD\|132476
NC_008536.1\|WP_049873201.1\|5997076_5997721_-\|methyltransferase-domain-containing-protein	unknown	unknown	gnl\|CDD\|225136
NC_008536.1\|WP_011686442.1\|5987427_5988021_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|143457

Protein	Function_ID	Function_description	E-value
NC_008536.1\|WP_011686433.1\|5973976_5975380_+\|aminopeptidase-P-family-protein	gnl\|CDD\|223085	COG0006, PepP, Xaa-Pro aminopeptidase [Amino acid transport and metabolism].	6.39847e-62
NC_008536.1\|WP_011683270.1\|5989780_5990137_-\|transposase	gnl\|CDD\|366690	pfam01527, HTH_Tnp_1, Transposase. Transposase proteins are necessary for efficient DNA transposition. This family consists of various E. coli insertion elements and other bacterial transposases some of which are members of the IS3 family.	0.00331396
NC_008536.1\|WP_083783834.1\|5978160_5979183_-\|selenide,-water-dikinase-SelD	gnl\|CDD\|273100	TIGR00476, selenide_water_dikinase, selenium donor protein. In prokaryotes, the incorporation of selenocysteine as the 21st amino acid, encoded by TGA, requires several elements: SelC is the tRNA itself, SelD acts as a donor of reduced selenium, SelA modifies a serine residue on SelC into selenocysteine, and SelB is a selenocysteine-specific translation elongation factor. 3-prime or 5-prime non-coding elements of mRNA have been found as probable structures for directing selenocysteine incorporation. This model describes SelD, known as selenophosphate synthetase, selenium donor protein, and selenide,water dikinase. SelD provides reduced selenium for the selenium transferase SelA. This protein itself contains selenocysteine in many species; any sequence scoring well but not aligning to the beginning of the model is likely to have a selenocysteine residue incorrectly interpreted as a stop codon upstream of the given sequence. The SelD protein also provides selenophosphate for the enzyme tRNA 2-selenouridine synthase, which catalyzes a tRNA base modification. It also contributes to selenium incorporation by selenium-dependent molybdenum hydroxylases (SDMH), in genomes with the marker TIGR03309. All genomes with SelD should make selenocysteine, selenouridine, SDMH, or some combination.	1.33924e-128
NC_008536.1\|WP_011686440.1\|5985973_5986933_-\|hypothetical-protein	gnl\|CDD\|276809	sd00006, TPR, Tetratricopeptide repeat. The Tetratricopeptide repeat (TPR) typically contains 34 amino acids and is found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi, plants, and humans. It is present in a variety of proteins including those involved in chaperone, cell-cycle, transcription, and protein transport complexes. The number of TPR motifs varies among proteins. Those containing 5-6 tandem repeats generate a right-handed helical structure with an amphipathic channel that is thought to accommodate an alpha-helix of a target protein. It has been proposed that TPR proteins preferentially interact with WD-40 repeat proteins, but in many instances several TPR-proteins seem to aggregate to multi-protein complexes.	5.11124e-06
NC_008536.1\|WP_011686435.1\|5977459_5978164_-\|orotidine-5'-phosphate-decarboxylase	gnl\|CDD\|234695	PRK00230, PRK00230, orotidine-5'-phosphate decarboxylase.	1.05102e-103
NC_008536.1\|WP_011686434.1\|5975449_5977429_-\|M13-family-metallopeptidase	gnl\|CDD\|341056	cd08662, M13, Peptidase family M13 includes neprilysin and endothelin-converting enzyme I. The M13 family of metallopeptidases includes neprilysin (neutral endopeptidase, NEP, enkephalinase, CD10, CALLA, EC 3.4.24.11), endothelin-converting enzyme I (ECE-1, EC 3.4.24.71), erythrocyte surface antigen KELL (ECE-3), phosphate-regulating gene on the X chromosome (PHEX), soluble secreted endopeptidase (SEP), and damage-induced neuronal endopeptidase (DINE)/X-converting enzyme (XCE). Proteins in this family fulfill a broad range of physiological roles due to the greater variation in the active site's S2' subsite allowing substrate specificity. NEP is expressed in a variety of tissues including kidney and brain, and is involved in many physiological and pathological processes, including blood pressure and inflammatory response. It degrades a wide array of substrates such as substance P, enkephalins, cholecystokinin, neurotensin and somatostatin. It is an important enzyme in the regulation of amyloid-beta (Abeta) protein that forms amyloid plaques that are associated with Alzeimers disease (AD). ECE-1 catalyzes the final rate-limiting step in the biosynthesis of endothelins via post-translational conversion of the biologically inactive big endothelins. Like NEP, it also hydrolyzes bradykinin, substance P, neurotensin, and Abeta. Endothelin-1 overproduction has been implicated in various diseases including stroke, asthma, hypertension, and cardiac and renal failure. Kell is a homolog of NEP and constitutes a major antigen on human erythrocytes; it preferentially cleaves big endothelin-3 to produce bioactive endothelin-3, but is also known to cleave substance P and neurokinin A. PHEX forms a complex interaction with fibroblast growth factor 23 (FGF23) and matrix extracellular phosphoglycoprotein, causing bone mineralization. A loss-of-function mutation in PHEX disrupts this interaction leading to hypophosphatemic rickets; X-linked hypophosphatemic (XLH) rickets is the most common form of metabolic rickets. ECEL1 is a brain metalloprotease which plays a critical role in the nervous regulation of the respiratory system, while DINE is abundantly expressed in the hypothalamus and its expression responds to nerve injury. A majority of these M13 proteases are prime therapeutic targets for selective inhibition.	0
NC_008536.1\|WP_011686448.1\|5997984_5999169_-\|6-phosphofructokinase	gnl\|CDD\|274155	TIGR02483, ATP-dependent_6-phosphofructokinase_1, phosphofructokinase. Members of this family that are characterized, save one, are phosphofructokinases dependent on pyrophosphate (EC 2.7.1.90) rather than ATP (EC 2.7.1.11). The exception is one of three phosphofructokinases from Streptomyces coelicolor. Family members are both bacterial and archaeal. [Energy metabolism, Glycolysis/gluconeogenesis].	1.01697e-76
NC_008536.1\|WP_011684349.1\|5988851_5989784_-\|IS3-family-transposase	gnl\|CDD\|222853	PHA02517, PHA02517, putative transposase OrfB; Reviewed.	4.11428e-52
NC_008536.1\|WP_063720758.1\|5980608_5983905_-\|TonB-dependent-receptor	gnl\|CDD\|379297	pfam13620, CarboxypepD_reg, Carboxypeptidase regulatory-like domain.	6.48614e-21
NC_008536.1\|WP_011686446.1\|5992756_5996746_-\|carboxypeptidase-regulatory-like-domain-containing-protein	gnl\|CDD\|379297	pfam13620, CarboxypepD_reg, Carboxypeptidase regulatory-like domain.	1.5552e-17
NC_008536.1\|WP_011686437.1\|5979207_5980608_+\|peptidase-C45	gnl\|CDD\|368190	pfam04916, Phospholip_B, Phospholipase B. Phospholipase B (PLB) catalyzes the hydrolytic cleavage of both acylester bonds of glycerophospholipids. This family of PLB enzymes has been identified in mammals, flies and nematodes but not in yeast. In Drosophila this protein was named LAMA for laminin ancestor since it is expressed in the neuronal and glial precursors that surround the lamina.	1.25025e-16
NC_008536.1\|WP_041859770.1\|5999848_6000952_-\|hypothetical-protein	gnl\|CDD\|226749	COG4299, COG4299, Uncharacterized protein conserved in bacteria [Function unknown].	2.10462e-27
NC_008536.1\|WP_011686439.1\|5984118_5985882_-\|hypothetical-protein	gnl\|CDD\|223679	COG0606, COG0606, Predicted ATPase with chaperone activity [Posttranslational modification, protein turnover, chaperones].	7.93164e-08
NC_008536.1\|WP_011686449.1\|5999311_5999653_-\|response-regulator	gnl\|CDD\|236838	PRK11083, PRK11083, DNA-binding response regulator CreB; Provisional.	6.37542e-07
NC_008536.1\|WP_157675923.1\|6001093_6001618_+\|sigma-70-family-RNA-polymerase-sigma-factor	gnl\|CDD\|274357	TIGR02937, RNA_polymerase_sigma_factor, RNA polymerase sigma factor, sigma-70 family. This model encompasses all varieties of the sigma-70 type sigma factors including the ECF subfamily. A number of sigma factors have names with a different number than 70 (i.e. sigma-38), but in fact, all except for the Sigma-54 family (TIGR02395) are included within this family. Several Pfam models hit segments of these sequences including Sigma-70 region 2 (pfam04542) and Sigma-70, region 4 (pfam04545), but not always above their respective trusted cutoffs.	9.81781e-20
NC_008536.1\|WP_011686445.1\|5990949_5992698_-\|tetratricopeptide-repeat-protein	gnl\|CDD\|131573	TIGR02521, Uncharacterized_protein_HI_0366, type IV pilus biogenesis/stability protein PilW. Members of this family are designated PilF and PilW. This outer membrane protein is required both for pilus stability and for pilus function such as adherence to human cells. Members of this family contain copies of the TPR (tetratricopeptide repeat) domain.	1.92966e-18
NC_008536.1\|WP_011686444.1\|5990218_5990944_-\|TIGR03435-family-protein	gnl\|CDD\|132476	TIGR03435, Soli_TIGR03435, soil-associated protein, TIGR03435 family. Bacterial reference strains encoding members of this protein family are all isolated from soil. These include 39 members from Solibacter usitatus Ellin6076, 27 from Acidobacterium sp. MP5ACTX8 (both Acidobacteria), and four from Pedosphaera parvula Ellin514 (Verrucomicrobia). The family is well-diversified, with few pairs showing greater than 50 % pairwise identity. A few members are fused to Peptidase_M56 domains (see pfam05569), to Sigma70_r2 domains (see pfam04542), or have a duplication of this domain.	1.25011e-89
NC_008536.1\|WP_049873201.1\|5997076_5997721_-\|methyltransferase-domain-containing-protein	gnl\|CDD\|225136	COG2226, UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis [Coenzyme metabolism].	1.93224e-26
NC_008536.1\|WP_011686442.1\|5987427_5988021_-\|hypothetical-protein	gnl\|CDD\|143457	cd07139, ALDH_AldA-Rv0768, Mycobacterium tuberculosis aldehyde dehydrogenase AldA-like. The Mycobacterium tuberculosis NAD+-dependent, aldehyde dehydrogenase PDB structure, 3B4W, and the Mycobacterium tuberculosis H37Rv aldehyde dehydrogenase AldA (locus Rv0768) sequence, as well as the Rhodococcus rhodochrous ALDH involved in haloalkane catabolism, and other similar sequences, are included in this CD.	0.00641203

>NC_008536.1|WP_011686442.1|5987427_5988021_-|hypothetical-protein
MQNEVNEVLDLGVVLGQNQAFGLIAGRCSAAQAESIRRIRTEQLYKRVTEHWRDFCPQYLKMSGSQADNIIRLWEEFGAGYFEVAQLTRVSPETYRAIEPAVENGVLNLNGEQIELTLENSRRVAAAVAEVRRTLPAKPVAELSFSERVARLDRLCQELTQEFTAIPDISAEAFQTYRISLLNLYTVLHKMRAQFRY
>NC_008536.1|WP_049873200.1|5987032_5987431_+|hypothetical-protein
MRRHGFRGYPVGTIIYYGPDNTRASKVAVGFAATESSESVILDRLYSDTGDVRTDPAIQAAILRILKEHGVKSVSMLENDHILGCPHEEGKDYPDGEVCPQCPYWANRDRFEGATDRADKARALADWARRQG
>NC_008536.1|WP_011686440.1|5985973_5986933_-|hypothetical-protein
MTLAMLANSIFCKSAAALLLAATLCAQPPMGGRGGPPMSDAMRQAQQLMRDGKLADALAIYEKENAGSQAGTVLDLMGKGAEARQHFQRAIDAAPDSAARANAQRSMAMSYAFEGDCRNTVKYEQMVIAYWATREQADPQNAFYQEGEMANEAARVCIDAGDLETAGAWYRKGTELGLKEPGNQTHPASLWKFRLEHALARIAARKGDKAEAQKHVAAAKAQLDGDPKMAEQQARFFPYLTGYVALYTGDYKQARDDFEKAIALPGNTADPFYQCLLGMTYEKLGEKEKATECYRKASATTGHNPPAAFAKPFTRKKLA
>NC_008536.1|WP_011686439.1|5984118_5985882_-|hypothetical-protein
MIAPLYVPREPDCLQATGLAESTLEALILKILYFRGDLYGQELSTAIGLRFSVIEEIVEALKQAHHIQIKKSLGMGTIGSTLALTETGRARAREALEANQYAGPAPVPLGQYIEVVRAQRQPDGWLNKASLARAFRGMVMTENLLTQVGPAVSAANSLLVYGKPGDGKTFLIESLSKVDSAPVFVPHAIECQGNIVLVYDPIDHHRVEEEEEEGPAVAIAREAPFDRRWVKCKRPFLMSGGELALDMLDLRYNGNSKVYDAPFQLKANNGIYLVDDFGRQRATPAELLNRWIVPMERRVDYLSFVSGGKMTTPFETFLVFSTNLNPADLGDEAFLRRLQYKIRLRGPAHNEFVRIFENACRERKLPCAPELLQGFLEKRYHQPGKAFRRCHPRDLLTHALNLIHFENLPYELTAEVLDQAFESCFLQGADDDAPAESKILRASSKPCADYWAGRTQAFTLFGRLAFLASCREHSTGHYRDQEALREFDAAEISSTLAALHIRVFVEWLSLNLDQQSRDLARYLSTPEGRAAFLSFDRRELTGILAPPDTKPQERRMFNNDLTTVLLALSQPHHQAEAVAPSQIERIA
>NC_008536.1|WP_063720758.1|5980608_5983905_-|TonB-dependent-receptor
MLAIHVVICSTAPYAWSQTVSGDLVGRVLDAAGSAVPNATITATNTGTNVNTKGTTNTSGEYRIGNLPPGNYDISAAANGFAKATLKNVAVQLNQIATANLTLQVGTVTTSVEVTEAPAVIDTTTAQVQNTFSSKASEDLPTTSNGFGVLNLSMLNAGVTSAGGIGVGIGTGPSVGGQRPRSNNFTVEGIDNNEKSTTGPEASIPNDAVAEFSVLQNQFTAEYGHSAGGQFNTVVKSGTNSVHGTVYEYMQNRDLNALDQHLAQQGILSNPRFDQNRLGATIGGPIIKDKWFYFGDFEYNPVGQAATAAGQLLTPTTQGYSILNGIPGLNATNLSILQKYVPASPAASSTISIGSTNVPVGVLPIAAPNFQNNYNGVASMDFNASDKDQIRGRFVFNHISFIDTTANLPVFYTTVPEKAYLATFTEYHTFSPRLTNEFRLGFNRLFQDFPSGNFSFPGLDQFPNLTFDELSLQLGPDPNAPQSQSQNTYQLTDNITWIKGNHTFKVGQDFRRYIAPQSFTQRLRGDYEYSTLELYLRDIAPDVFGERTLGQPRYYGNQTASYTYAQDTWRIRPNLSLNLGVRYEFTGEPWSASTQTLNSAASVPNVLEFNKPKTQTNAFAPRIGIAYSPGTSGNTSIRAGFGMSYDVLFDNIAILSLPPQLTTTADITNSQFSNLVGVPGFLANGGFGPNLSVSGQLTPQQARENTSGYITNQVLPYAIQWNFGIQHVFAKDYTFEARYLGTRGVHLPMQQQINRSSPVTGTNQIPTYMSAPGTAALAGLPLTVGDLRNMGNVLPQFGAAGFTSAITAYTSQGWSTYNGLALQANRRFTRGLQVQAAYTWSHLIDNSTTEFGATYLTPRRAQDFQNLTADKATSLLDRRQRFSFSAIYDAPWYRTNRSWFLKNLVGNWEIAPIYIYETPEYYTVQSGIDSNFNGDAAGDRVMVNPNGTAHTGSDIYGLDRSGNRIAVTAPAAQVNQVVAWVAVNPNARYIRAGYGTVPNAGRNTEAMQPINNIDLTLLKRFNITERLHLELSGQALNLFNHPQYIAGTPDAAQLPNNYSIYTPGVRSFVTVNSPTFNNSVATFSSNPRTMVLVGKITW
>NC_008536.1|WP_011686437.1|5979207_5980608_+|peptidase-C45
MRRTAVLSAVLLLVLGFTLVSREPQTDPRLKKALRSAERNGWIQVHLEGKPAEIGFQHGYLLSAEIKDAFHAVSAEMVHEEKKDWAFFRKAAEQVFWPRVEQEYRDELNGIVEGLKAKNVKLDLWDIVALNAWLELPYYDKWYDKSTGATSNAAGPGDHCSAFVATGSYTKDHRIIIAHNNWTSYSSGERWNIIFDVTPAKGSRFVMDGMPGLIHSGDDFGLNSAGILITETTISSFTGFDPNGIPEFVRARKAMQYSESIDDFARIMKEGNNGGYANNWLIADRRTNEVASLELGLKNVVLQRTKDGFFVGSNFPNDPKLIKEETDFDSKDRSKSENARHERWLALMDQNKGKIDTAAAQKFLGDHFDVFEGKQDYDERTLCGHVDSSPRGMGTWQPPYAPAGAVQNKVADAAGAEKMTMSAALGHACGRSFKSSEHLAKHPEFAWQKDMLRDMPARPWTKFVAK
>NC_008536.1|WP_083783834.1|5978160_5979183_-|selenide,-water-dikinase-SelD
MDETTQARKLTAHVKAAGUASKLSPKLLDKVLATVPRWPDANVLVGFDTADDAGVYRLSAELALVQTLDFFTPIVDDPYTFGAIAAANSLSDVYAMGGRPISALSILAYPAKGDMDDLAAILKGGAEKMHEASCSILGGHSVNDEEVKFGYSVTGTVHPARVKANAGARAGDALVFTKRLGTGVIGTALKRGIARDEDVAEATASMLTLNRTACEEMLSYDVGGCTDVTGFGLIGHAREMAIASGVTLEIESDALRFLPGAVEYARAGAVPAGLKNNREFAECAVEMARALPREIEDLLYDPQTSGGLLYTLPEAEAAKLKVAWRVGRVLPRGERAMRII
>NC_008536.1|WP_011686435.1|5977459_5978164_-|orotidine-5'-phosphate-decarboxylase
MTTKAMHNPIIVALDVESAAEAREMIARIGPRVNFYKVGLELYAASGMEVVKELLGQGKQVFLDLKMYDIPETVSRAVAQVAKTGVTFLTVHAVSSVMRAAVAAREGSKLRILGVTVLTSFGPEDMDDLGYDGTVGELVERRANKAAELGVDGVVASPLEAASVRRIVGPRVAIVTPGVRSAGVDAGDQKRIATPAQAMLDGADYLVIGRQITRAKDPAAAVDQVLMEIATALV
>NC_008536.1|WP_011686434.1|5975449_5977429_-|M13-family-metallopeptidase
MWKRVVFVSLLAAVCFAQHSGIDRTSLDPTCKPCQDFWRYANGGWLDKNPIPARFPSWGPASVLSENTRANLRGILEAAKGTKAGDVYAACMDTAAIDAAGVKPLQPYFDRVAAIGSAKELSAGLVAAQSVTGVGPFTLQQLGDLKNSKDIILYVDSGGLSLPERDYYFKDDARSKQIREEFVKHVARMLELAGTQPEAAAAQAQTILAFETKLADATKTAVQRRDIPAMYHKVDFAGLTAMAPDFDWKLLFNELHLSTSAPINVTEPEFLKRFNQQLTSESLADWKTWLRWRLLTGSAGRLAKPIFDENFHFRSTVLTGVTEQQPRWRTCVGMADGSVGEELGKLYVDKYFPPQSRQRAKDLVENLRVTLGEQIQGSEWLAADTKRNALLKLKAFNSKVGYPDRWRDYSGLKVDAKSYFENAVASYRFERAYQMSKIGKPIDRNEWEMTPPTLNAYYNPLMNEIVFPAGILQPPFFDGQGDDATNYGAIGAVIGHEMGHGFDDQGSQFDAEGNMKNWWTPADLKSFTTRAGCVVEQYDTLDLGDGAHHKGKLVVGEAMGDLNGLKLAYRAYHRALKGKEAPVIDGFTGDQRFFLAFARVWGSQTRPEAVQLQTNTDPHPIAKYRAIGTLQNMPEFRKAFECQGTDKMVRVDEKQCSLW
>NC_008536.1|WP_011686433.1|5973976_5975380_+|aminopeptidase-P-family-protein
MKKFWLLFSLTVVAFAQPPLFTDSLPKEEFAQRRARLMEQIGDGIAVVQGATEDAAYVKFRQNNHFFYLTGVESPRAILLLDARTKSATLYLTPRNERAERSEGPLLAPGEEAAALTGIPVVADRARFADDIKKLGAERSVLYTPYRPESQAAVTPDRSAVHLAATAADPWDGRPSRETVFREKLQAQAPRLEIKNIDPILDAMRSIKSPRELALIREATRIAGIAMIEAMRAAKPGMYEYEIEAIGDYVFKKNNAQYPAYFGLVAAGTNSFWPHYHAAQAQLKPGDLVLFDYAPDYKYYASDVTREFPASGKFTAAQRDLYGVYVDLYRALMTSIRPNVTARAVMQDAVKKMDAIMASHQFTKETYRQAAQRFVESYRNNVGRSLGHPVGMEVHDVQSPQELLKPGYVFTIEPALTVPEERIYIRLEDVLVITESGYENLSAFVPETIDEVESAMSGAKVAIPAKR
>NC_008536.1|WP_011684349.1|5988851_5989784_-|IS3-family-transposase
MTQEQGKLSIQRMCQLVGVSRAGYYRHWEVVAPDEAEMAARDAIQKVVLAHHRRYGYRRVTAQLHRQGNIINHKRVLRIMGEDNLLAIRYRKYIMTTDSRHDYPVYVNLAARMTLTGINQLWIADITYIRLRREFVYLAIVLDRFSRKAIGWSLDRALAARIAVAALEQAVERRQPPPGVVVHNDQGIQFVCHEFQEVVKAHGMVPSLSRPANPYDNAACESFMKTLKQEEIYCHRYQDFDELSAHVEEFIETYYNRQRLHSALGYRTPEEFERDGISAPNSGTHNAATMLVFTPKEEEGSGGPDSISPR
>NC_008536.1|WP_011683270.1|5989780_5990137_-|transposase
MAKMKKWRRHTIEFKRQAVERMKTCENIEALARELKIQRKLLYTWRYQLEGRPEPRHANLGIAAEDRKEKRLREENAKLKSALADKVLEIELFQHALLKLKEARPQPGASASTKSSVR
>NC_008536.1|WP_011686444.1|5990218_5990944_-|TIGR03435-family-protein
MHRLLLALVAAVLCSQPRPEFDVASLKPVILDGQDSYRSNLGSVQHGVLTMTNVTLADCLRVAYGIPTEDQIAGPAWIKSKSVRFDITAKAAPDTTRDAAFRMLQPLLEQRFQMVYHHEDREMSYLAMTVAKTGSKLEPAKEPPEGVTSLRGNHIQHHHIDMPLLAYLISRFTRTRVLDMTGVKGYFVVDLSWAPDDAPADVEGLSIQNAIQKQLGLKLEARKGPVDTLVVDKASETPLGN
>NC_008536.1|WP_011686445.1|5990949_5992698_-|tetratricopeptide-repeat-protein
MAKSRNFGIYVLLAIAVFAAYAPVLHFDFVTYDDPDYVTANPRVQAGLSAAGIAWAFGAGYAGNWFPLTWLSHMLDVSLFGLDAGWHHFTNLWLHALSTLLWFAVLQRLTGARWRSALVAFLFGLHPLHVESVAWVAERKDVLSGLFWPLTLWAYAAYTARPGVWRYTATLALFCLGLMAKPMIVTLPLVLLLLDRWPLRRGTKLLEKLPFFAGSLAISILTFLVHRDIGAAATLTLIPLATRLENALISYCAYVLQMLWPANLAVFYPYPQGSLAIPAALAGIAIALVTAFTIRAFPRRPYLAAGWLWYVITLLPVIGLVQVGAQARADRYTYIPMIGLAIALVWGAAEALDRRPRIRMSAAIAVCAACLALTWQQVQYWRDSVALYRHAIAVTDENYVAHYNLAAVLETRGDLAEAAAELRETVRIRPRFAPAHSELGQVLGKLGLPGEALPALQQAKSLQPDLTDIDLRLGAVLGSLGRADQAADAFAEAVRLQPGNGDAHYNYGISLAQQGKLHDAAREFRATVQLRPSDVEARFNLGIAAASLGRTDEAVAQFREALRLRPQFPEAQQELGRLIQVK
>NC_008536.1|WP_011686446.1|5992756_5996746_-|carboxypeptidase-regulatory-like-domain-containing-protein
MTSFRSRSSLWFSALLLGIFIASSALPAWSQATSTATVAGLVTDEQNAAVVGAEVHLLDNATGSSQTTLTNDTGRYVIVNVQPGTYTVTVSKQGFTVHKISAQKVDVGSSLMINAILKVGSTSTTVEVTASAGADLQTTNATVGNTLTSAALMLLPNMGRDVSTLAVLQPGTTPSGMTAGSFSDQNVFMLDGGNNSDDMAGNNTSYVTNFTGTGGTQTNGSPSGIVPTPVESIEEFKVGSFNQTADFSGSIGAQVQMVTKRGTNAYHGSAYGFYFATNVGAANSWANNHTPANGLSYTALPSNHRSRFGGSLGGVLFPKLLGGKTYFFVNYEGSRFPNVGTIEKNSPSALLRAGVIQVADATGKYQAYNLNPNPVTVNGVTYQPAQCGGTACDPRGIGLNPVVQKLWQYMPMPTDFTGAAGDGANVGGYISSIRAPLTSNAYVSRIDHDFNEKNRFFATYRYTTVTSLTTNQVDIGGLTSGATLGTPKAVAPRVQKPSFWVLGLTSSITPTITNDFRWNYSRNFWQWFSLGDPPQLAGLGGAVEIAGESTNALIPYNVNTQSTRTRYWDGQDNLFKDDVTIIKGNHLFQVGGSYQRNYDQHSRTDNGQGINNQIVYQVTSSNINFGNFNYPAGMPASQSSNFNTYYSYVLGMVSQSQLVYTRSGSNLALGPIGASALAQSTIPYYNSYVADTWHIKPSVTLSYGLSYQLEMPPNEVNSKQVDMVYQDGSQVDAASYMAQRTKAALAGSVFNPTLAFATVNNIGAGKKYPYDPFYGGFSPRFSIAWNPKFNDGIMHKLFGSNDTVIRAGYGRLFGRLNGVNQLLVPLLPPGLLQAVSCTGVSRVSGGNQCLGNNGVDPSTAFRIGPDGMSAPLPFVSPTLAQPYVPGLNGNAGASDVTALDPKYRPERTDNLTVSLQRQINKTVSMEVGYIGRIIRNEMLPINLDSVPYMTTLGGQTFSDAFSKIYFPVVAGGVPAAQPFFEAALGGPNSAYCAGFASCTAAVVSKSANVTAIKNTAVSDLWTALYKSPGWTLGRSLVAQPLAGTTVSQGYTYLLNTALGYGNYNALFITHHIRDFHGITATSNFTWGRALGTGTTSQATSSNTALDNYNLQNNYGLQSFDIKFVYNIAMYYSPKVFLSQKGIAGKLLGGWVFSPLFTAQSGNPIQPGYSEGGCSDCQAFGEVSTTSSATTAFTTNAQAAAPYTGGSNANYNVAGSGGVGTNNSGGVNMFADPAAVLAQFRKCVLGFDGNCGGFALRTVPRWNVDLGVHKTVAMFREGMGADFSFQFTNVMNHVVMGSPALTTTTPSTFGRITSQANTPRNMEFGLRLHF
>NC_008536.1|WP_049873201.1|5997076_5997721_-|methyltransferase-domain-containing-protein
MNWKRFFSKPENAHLTPELRARIQASFDQAASDEEHFPSTIDPRIYHVKLIREHLGELRGRRVLDVGCGKGRFARVFQSQEPEAELWGLDISEEMLRFVPAGIHTRAGSMTELPFEDAFFDGAYATESLEHAVEIEKAVSEICRVVKPGGRIVVIDKNAEHWGRLDTPEWEKWFTPKQLERLLAQHCAHVSSRLISYWEDVEPDGLFVAWLAVK
>NC_008536.1|WP_011686448.1|5997984_5999169_-|6-phosphofructokinase
MAGKRIGILTGGGDVPGLNSVIKTVVYRGSEIGCEVIGIRRGWEGLTHVNLQDPASRTRYVLPLNRENTRTIDRTGGTYLHSSRTNPSKMKKLPPVLEGQDFPKVTSTKKGVTSEVFDVSKAVLKNIETLNLDYLIAIGGDDTLSYAAELDRQGFRVIAVPKTMDNDVQNTEYCIGFSTAITRAMDAIERQRTTVGSHERIGLFRVFGRDAGYTALYTAYVTSVRCCIPEHKVDLPKLIDLLVTDKKNNPSNYSLAILSEGAEWVGYTVKEYGEADAFGHRKKMSVAEDLSNEIKNSTGEETIVSDLTYDLRSGSADFVDRMVASTFAGMAMDAIQEGKHGLMTAISNGSYTMVGIPDPKLGPRRVDVASMYNTDRYRPVYDHKLGLPIFLTRA
>NC_008536.1|WP_011686449.1|5999311_5999653_-|response-regulator
MAKILLLGLDSPIADDLIKVLQQLGQSVQTAALGSGALDSGDVNLVFAGSGDLCAIRRSRPDLPVVVVSRLPEVSAWLDALEQGAADYCGAPFERKQVSWVLNSSLPAFPTAA
>NC_008536.1|WP_041859770.1|5999848_6000952_-|hypothetical-protein
MDTYRGFVMLLMMAEVLQLSRVAKALPGSAFWSFLAYHQTHVEWAGCSLHDTIQPGFSFLVGVALPYSIAARLAKGGAFRAMFLHALWRSFLLIALGIFLRSTHAPQTYFTFEDTLTQIGLGYPVLFLLAWRPPRWQWIAFGMLLSGYWLAWALYPAHEPGFYSGFLAHWNKGDNFGNAFDVWFLNLFPRTKPFHENGGGYLTLSFIPTLGTMLLGLAAGRWLRTAAPAIPIRRLLAAGAIGVAAGLLLHFAGICPIVKRIWTPAWTLFSGGLCFFFLAGFCWLTEIKGYRKWAFPLVVIGANSIAAYLMAHLWERFIIDSFRIHLGPNAFLFLGAPYEPVLRGTMVLMAYWLILYWMYRRQIFLKV
>NC_008536.1|WP_157675923.1|6001093_6001618_+|sigma-70-family-RNA-polymerase-sigma-factor
MDGEQDGRYRAAAAEYGAAIERLARAYEADPDWRRDLVQEIHLALWRSFAGWEGRCSVRTWVYRVAHNAATSHVIRQRRTNAHVLVSVEELEAAPDSVNAEEAAGQRAALDRLLGLVQQLKPLDRQVILGYLEGLDAASIGEITGLAPGNVATKIHRIKNLLSRQFHQGVRHGE

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Crispr_ID: NC_008536_10

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_008536_10

6146947-6147040

Orphan

Consensus_repeat	Method
CCTTTGTGGGGCAGCCAATCCTGGCTG	CRISPRCasFinder

1 spacers

The CRISPR arrays of NC_008536_10

>merge|NC_008536|10|6146947-6147040|CRISPRCasFinder
CCTTTGTGGGGCAGCCAATCCTGGCTGTCGCGATGGCGCTGCGCGCCATTTAAGGGGATGAAAAACCCCTTTGTGGGGCAGCCAATCGTGGCTG

>NC_008536|10|10|6146947-6147040|CRISPRCasFinder
CCTTTGTGGGGCAGCCAATCCTGGCTG	TCGCGATGGCGCTGCGCGCCATTTAAGGGGATGAAAAACC
CCTTTGTGGGGCAGCCAATCGTGGCTG

Protein	Signature genes	Signature genes Name	Protein_function
NC_008536.1\|WP_011686582.1\|6152846_6153125_+\|GlsB/YeaQ/YmgE-family-stress-response-membrane-protein	unknown	unknown	gnl\|CDD\|225170
NC_008536.1\|WP_011686578.1\|6148222_6149800_-\|transglycosylase-SLT-domain-containing-protein	unknown	unknown	gnl\|CDD\|381606
NC_008536.1\|WP_083783842.1\|6138719_6140639_+\|polysaccharide-biosynthesis-protein	unknown	unknown	gnl\|CDD\|224011
NC_008536.1\|WP_011686576.1\|6145566_6146814_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|226433
NC_008536.1\|WP_049873211.1\|6151987_6152611_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|235906
NC_008536.1\|WP_011686571.1\|6140678_6141629_+\|hypothetical-protein	unknown	unknown	unknown
NC_008536.1\|WP_011686573.1\|6142883_6143942_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|200555
NC_008536.1\|WP_011686569.1\|6137487_6138714_+\|DegT/DnrJ/EryC1/StrS-aminotransferase-family-protein	unknown	unknown	gnl\|CDD\|223476
NC_008536.1\|WP_011686587.1\|6156407_6156926_-\|DUF4136-domain-containing-protein	unknown	unknown	gnl\|CDD\|379281
NC_008536.1\|WP_011686577.1\|6147196_6148192_-\|polyphosphate-kinase-2-family-protein	unknown	unknown	gnl\|CDD\|274737
NC_008536.1\|WP_011686585.1\|6153918_6154848_-\|DUF2950-domain-containing-protein	unknown	unknown	gnl\|CDD\|371539
NC_008536.1\|WP_083783841.1\|6136657_6137491_+\|sugar-transferase	unknown	unknown	gnl\|CDD\|376775
NC_008536.1\|WP_011686586.1\|6154882_6156325_-\|DUF3300-domain-containing-protein	unknown	unknown	gnl\|CDD\|378701
NC_008536.1\|WP_011686572.1\|6141628_6142882_+\|DegT/DnrJ/EryC1/StrS-aminotransferase	unknown	unknown	gnl\|CDD\|99740
NC_008536.1\|WP_011686583.1\|6153192_6153573_-\|hypothetical-protein	unknown	unknown	unknown
NC_008536.1\|WP_011686567.1\|6136145_6136826_+\|GNAT-family-N-acetyltransferase	unknown	unknown	gnl\|CDD\|223532
NC_008536.1\|WP_041858171.1\|6150715_6151903_-\|hypothetical-protein	unknown	unknown	unknown
NC_008536.1\|WP_049873210.1\|6144790_6145552_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|377205
NC_008536.1\|WP_011686579.1\|6149821_6150553_-\|aquaporin-Z	unknown	unknown	gnl\|CDD\|235453
NC_008536.1\|WP_011686574.1\|6143931_6144756_+\|phosphosulfolactate-synthase	unknown	unknown	gnl\|CDD\|376895

Protein	Function_ID	Function_description	E-value
NC_008536.1\|WP_011686582.1\|6152846_6153125_+\|GlsB/YeaQ/YmgE-family-stress-response-membrane-protein	gnl\|CDD\|225170	COG2261, COG2261, Predicted membrane protein [Function unknown].	1.18861e-07
NC_008536.1\|WP_011686578.1\|6148222_6149800_-\|transglycosylase-SLT-domain-containing-protein	gnl\|CDD\|381606	cd13403, MLTF-like, membrane-bound lytic murein transglycosylase F (MLTF) and similar proteins. This subfamily includes membrane-bound lytic murein transglycosylase F (MltF, murein lyase F) that degrades murein glycan strands. It is responsible for catalyzing the release of 1,6-anhydromuropeptides from peptidoglycan. Lytic transglycosylase catalyzes the cleavage of the beta-1,4-glycosidic bond between N-acetylmuramic acid (MurNAc) and N-acetyl-D-glucosamine (GlcNAc) as do goose-type lysozymes. However, in addition, it also makes a new glycosidic bond with the C6 hydroxyl group of the same muramic acid residue.	1.56847e-63
NC_008536.1\|WP_011686577.1\|6147196_6148192_-\|polyphosphate-kinase-2-family-protein	gnl\|CDD\|274737	TIGR03709, PPK2_rel_1, polyphosphate:nucleotide phosphotransferase, PPK2 family. Members of this protein family belong to the polyphosphate kinase 2 (PPK2) family, which is not related in sequence to PPK1. While PPK1 tends to act in the biosynthesis of polyphosphate, or poly(P), members of the PPK2 family tend to use the terminal phosphate of poly(P) to regenerate ATP or GTP from the corresponding nucleoside diphosphate, or ADP from AMP as is the case with polyphosphate:AMP phosphotransferase (PAP). Members of this protein family most likely transfer the terminal phosphate between poly(P) and some nucleotide, but it is not clear which. [Central intermediary metabolism, Phosphorus compounds].	2.2025e-151
NC_008536.1\|WP_011686576.1\|6145566_6146814_+\|hypothetical-protein	gnl\|CDD\|226433	COG3919, COG3919, Predicted ATP-grasp enzyme [General function prediction only].	3.11801e-48
NC_008536.1\|WP_049873211.1\|6151987_6152611_-\|hypothetical-protein	gnl\|CDD\|235906	PRK07003, PRK07003, DNA polymerase III subunit gamma/tau.	4.63754e-06
NC_008536.1\|WP_083783842.1\|6138719_6140639_+\|polysaccharide-biosynthesis-protein	gnl\|CDD\|224011	COG1086, COG1086, Predicted nucleoside-diphosphate sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism].	0
NC_008536.1\|WP_011686573.1\|6142883_6143942_+\|hypothetical-protein	gnl\|CDD\|200555	cd10929, CE4_u5, Putative catalytic domain of uncharacterized bacterial proteins from the carbohydrate esterase 4 superfamily. This family corresponds to a group of uncharacterized bacterial proteins with high sequence similarity to the catalytic domain of the six-stranded barrel rhizobial NodB-like proteins, which remove N-linked or O-linked acetyl groups from cell wall polysaccharides and belong to the larger carbohydrate esterase 4 (CE4) superfamily.	1.38604e-88
NC_008536.1\|WP_011686569.1\|6137487_6138714_+\|DegT/DnrJ/EryC1/StrS-aminotransferase-family-protein	gnl\|CDD\|223476	COG0399, WecE, Predicted pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis [Cell envelope biogenesis, outer membrane].	1.08625e-158
NC_008536.1\|WP_011686587.1\|6156407_6156926_-\|DUF4136-domain-containing-protein	gnl\|CDD\|379281	pfam13590, DUF4136, Domain of unknown function (DUF4136). This domain is found in bacterial lipoproteins. The function is not known.	3.79752e-38
NC_008536.1\|WP_011686585.1\|6153918_6154848_-\|DUF2950-domain-containing-protein	gnl\|CDD\|371539	pfam11453, DUF2950, Protein of unknown function (DUF2950). This is a bacterial family of uncharacterized proteins.	2.49569e-149
NC_008536.1\|WP_083783841.1\|6136657_6137491_+\|sugar-transferase	gnl\|CDD\|376775	pfam02397, Bac_transf, Bacterial sugar transferase. This Pfam family represents a conserved region from a number of different bacterial sugar transferases, involved in diverse biosynthesis pathways.	2.11474e-75
NC_008536.1\|WP_011686586.1\|6154882_6156325_-\|DUF3300-domain-containing-protein	gnl\|CDD\|378701	pfam11737, DUF3300, Protein of unknown function (DUF3300). This hypothetical bacterial gene product has a long hydrophobic segment and is thus likely to be a membrane protein.	3.80379e-112
NC_008536.1\|WP_011686572.1\|6141628_6142882_+\|DegT/DnrJ/EryC1/StrS-aminotransferase	gnl\|CDD\|99740	cd00616, AHBA_syn, 3-amino-5-hydroxybenzoic acid synthase family (AHBA_syn). AHBA_syn family belongs to pyridoxal phosphate (PLP)-dependent aspartate aminotransferase superfamily (fold I). The members of this CD are involved in various biosynthetic pathways for secondary metabolites. Some well studied proteins in this CD are AHBA_synthase, protein product of pleiotropic regulatory gene degT, Arnb aminotransferase and pilin glycosylation protein. The prototype of this family, the AHBA_synthase, is a dimeric PLP dependent enzyme. AHBA_syn is the terminal enzyme of 3-amino-5-hydroxybenzoic acid (AHBA) formation which is involved in the biosynthesis of ansamycin antibiotics, including rifamycin B. Some members of this CD are involved in 4-amino-6-deoxy-monosaccharide D-perosamine synthesis. Perosamine is an important element in the glycosylation of several cell products, such as antibiotics and lipopolysaccharides of gram-positive and gram-negative bacteria. The pilin glycosylation protein encoded by gene pglA, is a galactosyltransferase involved in pilin glycosylation. Additionally, this CD consists of ArnB (PmrH) aminotransferase, a 4-amino-4-deoxy-L-arabinose lipopolysaccharide-modifying enzyme. This CD also consists of several predicted pyridoxal phosphate-dependent enzymes apparently involved in regulation of cell wall biogenesis. The catalytic lysine which is present in all characterized PLP dependent enzymes is replaced by histidine in some members of this CD.	2.32282e-51
NC_008536.1\|WP_011686567.1\|6136145_6136826_+\|GNAT-family-N-acetyltransferase	gnl\|CDD\|223532	COG0456, RimI, Acetyltransferases [General function prediction only].	5.6792e-08
NC_008536.1\|WP_049873210.1\|6144790_6145552_+\|hypothetical-protein	gnl\|CDD\|377205	pfam04029, 2-ph_phosp, 2-phosphosulpholactate phosphatase. Thought to catalyze 2-phosphosulpholactate = sulpholactate + phosphate. Probable magnesium cofactor. Involved in the second step of coenzyme M biosynthesis. Inhibited by vanadate in Methanococcus jannaschii. Also known as the ComB family.	6.42873e-34
NC_008536.1\|WP_011686579.1\|6149821_6150553_-\|aquaporin-Z	gnl\|CDD\|235453	PRK05420, PRK05420, aquaporin Z; Provisional.	2.44074e-131
NC_008536.1\|WP_011686574.1\|6143931_6144756_+\|phosphosulfolactate-synthase	gnl\|CDD\|376895	pfam02679, ComA, (2R)-phospho-3-sulfolactate synthase (ComA). In methanobacteria (2R)-phospho-3-sulfolactate synthase (ComA) catalyzes the first step of the biosynthesis of coenzyme M from phosphoenolpyruvate (P-enolpyruvate). This novel enzyme catalyzes the stereospecific Michael addition of sulfite to P-enolpyruvate, forming L-2-phospho-3-sulfolactate (PSL). It is suggested that the ComA-catalyzed reaction is analogous to those reactions catalyzed by beta-elimination enzymes that proceed through an enolate intermediate.	1.93506e-82

>NC_008536.1|WP_011686576.1|6145566_6146814_+|hypothetical-protein
MNPATPVVVLQSGHHGALGIVRSLGRLGVPVYCVDTDWWEPASSSRYCRGRFLLKPDSDPAETLARLLEIAHQLGGRPILIPTTDEGAIWAAEHAAALESAYNFPRVDASLVRILCDKGRMQELARQSGVPTAQAMIPGSKTDVERFIETAVFPVMVKATDAGRMRRRAGGTKFVIHTPRELLDLYAKADDHQAPSLLIQEFIPGDDWMFDGYFDRGSQCLLGVTGKKIRRFPVDTGVTSLGVCLDNRAVQETTRKFMKSIGYQGILDIGYRYDRRDGQYKVLDVNPRIGCTFRLFTATNGMDAARALYLDMTGQPVAASSAAEGRKWLVEDFDLFSAIRSYRDGNLNVRDWARSFRGVEEAACFALDDPLPFLMMGVSDCCDFYGWLRSQRAIRHTPASQEIPPQLSPSPAPEE
>NC_008536.1|WP_049873210.1|6144790_6145552_+|hypothetical-protein
MHKSVVIDYLPESVRRYHPEWAIVAVDVIRATTTAITAAAMGRRCFPAPTIAAALALAGEFEHPLLAGESGGKMPAAFEMDNSPSQLAGRNDIDRPLVLVSSSGTKVIDEAAGCEAIYLACYRSYSVLASYLDGRHDRVAVIGAGSLGEFREEDQICCAWVAARLMEQGYVPENRETTAIVARWRDAPPEACLGSRSVEFLKRTGRTNDLDFILGHIDDLRHVFAVRNGEVKMISGRAPVKRDEQPEEAVVEC
>NC_008536.1|WP_011686574.1|6143931_6144756_+|phosphosulfolactate-synthase
MIHRNSIHTHEYLTLIGVPEMPPLTSPFDPGYDPATLESHLEQSSHLMAILKISMACWMVAKEDSTRRKVAAAIRHRVPTVTGGGPFEIAVAQDCLPAYLDLCADIGFTRIECGEGFTDMSLGAREVIGMAERRGLEVQFELGKKHGGAFSSDTTEQLISQGRRWLDAGARELVVEARESAKGVGLFDNDGEFNGTLADRFAHEFSLDTVTFEAPNKPSQFALLDHFGPQVRLCNIRLEELLRVEIYRRGLHSDAFCKDNLRPHLVKEEILRAS
>NC_008536.1|WP_011686573.1|6142883_6143942_+|hypothetical-protein
MANESYDVRSEFETGAFIMSLDTEQIWGYVDQMNDAQFHDRYPDALGAHEKLLACLCKAGVSATWFMVGGMALRGSEGMRDLRMAGLPEHWTSRIPSGDEASKPFWYRHSFVERLRKARPFQEIGLHGGLTHLIWTDADATREVVGRELAEGVKALEEASVRPLSFSYGREQEACYALLPVHGIKCYRGRTVTRAYQLGPTLHGAVARLFDEIRRATPPPVWPLETLPGLWSIPSSTFLYPIGASRSRVVGLRARVERFKRGLEAAARLRGIFHYCLHPENLTESPHGFSMFEEMLELLIRARDRGDIEVLTMTKAAARMERGRERELPSDALTGVSAGGSETDSKGHIHDS
>NC_008536.1|WP_011686572.1|6141628_6142882_+|DegT/DnrJ/EryC1/StrS-aminotransferase
MPHSRLYSIPRFALPYTSGDFAAGLRAAFSSTPPPDGFGLLGGSPKFWTRSGRQALRLLLGALDLKPNSGVALPLFTDPSLVRAIVAAGHRPVFIDVDARFLTMDPGCLEDARGMYSAVVAVHLFGQLADMPAILAASGGAPVLEDAAHAPLSYLHGRMAGRFGAAAFYSFASTKYWPAGGGGLAIVHHANIARRLADSTRVLSQPSRVEELRGLVLQAAKAVIFQRRLYGFFGKPLRRWTDRLGLLEPCLDLKAIQRPWAAVACRQAMRFSERVEMQRANSLRLLARLAGLPDVVLPRERPGAQYNYHIFPVLLHDREERAAVMRSMWSRFVDTSMIYAGVVRECRKFGYEGGCPVAESIADRLITLPNYAGLTGEDIDQIAEVFLSDLVAWRARASRGLKGAETEYVGEPLKRYT
>NC_008536.1|WP_011686571.1|6140678_6141629_+|hypothetical-protein
MLPSALVEAQLSREDAADARFPGSTLARFLELRGRRIVRACGALWYSVPGRFLMSVPYQQMLNPDPGELRRVIRDAGVCGARFPSLEWTGLDSGLYVLRRCKYDIKSLHIKHRPRVKHGMQHFEVRPATQAELLEQGCTLNLSTMARQGRYDPEFGEAPRWRKFVEAAFACPGVSFPAAFSGSRLAAYMVTCREQGWLHILHQMSRQEDLPDFPNHLLTYTITAQGAADESLEAVCYGYVPLFSADGLHEYKLRFGYEMVPHCSAIQLHPVLKTVLDHPVARAVVAAARRVRSNSQQLETIETVLQGARSSGRRLA
>NC_008536.1|WP_083783842.1|6138719_6140639_+|polysaccharide-biosynthesis-protein
MHMKNHRNIDVWLERACHLTVVGLSLTAAFLLRFDFAIPASVVPIWKQALLIAILVKLPIFDWVGFYRSLRRFVSIPDLYLVFLGNVAGSLLLAAMSMFFTGPAMPRSVLIMDGILCFVATALVRFSVRIYNATFRERSAEQRTGILIYGAGAAGAELAREIHANRNTKYEVKGFLDDDPLKQNARIMGIPVLGQGREAYSVVRQRNRRGPSVGEIIIAMPSATGQQMRETLANCRAAGVPCKTIPGIDELLSGRVLLAQVRNPSVQDLLGRQQVRLDEAHVAASIAGRSVLVTGAAGSIGSELCRQVARFGPGCLIAFDQAESDLFRIENELRERYPELELVTALGNIREAERLSEVMRQHAVESIFHAAAYKHVPMMESHPLEAVCNNVLGTWNLVRAARGHNVRNLLMISSDKAVNPSCVMGATKRVCERIVSSRWPGNGQTKCVSVRFGNVLGSNGSVVPVFQAQIAAGGPIKVTHPDARRFFMTISEAVSLVIQASTRTEGSEIFVLDMGEPIRIVDLAENMIRLAGKVPYEDIDIQFTGMRPGEKLMEEIRGKSERLIPTSMEKMHAIQEQPLVWDKINGWIEELKELIAERQERRIIAHLQTLVPEYTPSMRGAPQPVIMLPVKRPSELRSA
>NC_008536.1|WP_011686569.1|6137487_6138714_+|DegT/DnrJ/EryC1/StrS-aminotransferase-family-protein
MIAPFIHFHRPSIGEEEISEVVETLRSGWLTTGPRAARFERDFQEYTGAPHAVAVNSATAGLHIALAALKIGPGDEVITTPMTFCATVQTILHVGATPVLADIGWDGNIDPQEIAARITDRTKAIIPVHMAGLPCDMASIWSLARKHGIHVIEDAAHAAGARYAGLPIGSGESDAVAFSFYATKNLTTGEGGMITTQREELAQTMRMLALHGVSHEAWDRYSEKGSWQYDVLAHGFKYNLSDIQAALGIHQLRKLDEFIERRTRYARMYDTAFAGMEEVETPPDNPQCRHAWHLYIPRLNLRRLKLNRARFIRELQQRGIGTSVHFIPIPLLRYFARLPLAQYACPRALDLYPRIVSLPLYPAMTEEQVQYVARNVRELLESSRRGRLVAAGTPAAMVPATVSDIAGS
>NC_008536.1|WP_083783841.1|6136657_6137491_+|sugar-transferase
MHLFDHGRGRQRCGQRVLSRCRIQADAAIPAAQRTLDERIRDRRHGGRQHLRDTSITRSRRPRQTWCRIFDVACAAAGLLLLLPVLAAIAAAILWDDGAPVFFTQTRVGKRGRPFRIWKFRTMRAGSRGSAVTAAGDQRVTRTGAVLRRFKLDELPQLFNVLKGDMSLVGPRPEVPEYVQLEAPIWQAVLQVRPGVTDLATLLYRDEENLLGTSGDPNELYRETVLPAKLMLNLGYLHSRSFPRDLKLIGLTIRYSLFPEHFDPELIKRTLGTEVLK
>NC_008536.1|WP_011686567.1|6136145_6136826_+|GNAT-family-N-acetyltransferase
MTQTYPTDEPPSTSGGRRIVRVARVGDLPGIVDIHQKAFSHFFLTQMGGEFLRNYYALVLDYRAGIILVSEGDGLLEGFACGFIDPAEFYRLMWRSRRNFALPVLSALVRHPSLAAKVLSGVHRIHAPETEWPARSCELSSIAVAPETSGSGLGKVLMRAFLAQARRMDAECIYLTTDADGNDAVNAFYRDVGFKPTRRFLQRKGRWMNEYVIDGMEAGNTCETHL
>NC_008536.1|WP_011686577.1|6147196_6148192_-|polyphosphate-kinase-2-family-protein
MQNLFTKLILEPGIKIKLDEIFPGRRTPLRELGPPEIQPRVRRVDPIQLSDPYHEFLVQPGRRVKLSEIDPGYRGRYESGEAAAPEIQSLVKRLDHLQYVMFAERKHSLLIVLQGLDACGKDGVIRHILAGMNPAGCRVVGFKRPKPEELDHDFLWRVHPHLPAKGEVSIFNRSHYEDVLAFRVHHFTQVDLWARRYELINDFERLLVTENDTTVLKFFLYISKAEQLARFKQRLDDPTRRWKISEADYRERAHWARYTEAFEEMLSRTSTRHAPWFVIPANNKWFRDLTVSQIVSRTLEDLNMQCPEPVVDIAEIRRRYHAADREEAQAS
>NC_008536.1|WP_011686578.1|6148222_6149800_-|transglycosylase-SLT-domain-containing-protein
MLWPSRHAFATCGGVILLVIFAACSGGGKPVTRAETKTVEQAPPAPETAPPQGVAHRVTAAANIVTRGPIEQRLVREKWHGDLDRIARRRFLRVLVTPSKLGFHFAGGQMLGAIHEVCREFEKFLSKKLNTGNLSIEAVFIPVSRETLIPMLEDGSGDLVASLVGASERYQESVDYSDPVWDGAKAVIVSGPSAPPIGQLSDLAGQEIYYYRDTIPFDKLGQLSESFKEKGKQPIQLTATDRDLQADDLLEMVNAGLVPMTVAEERVATVFARILPHLLINSGVVVAEGPVRWAIRKNTPQLKAAVNEFIQSHRPGTAYGNMVARRYLRDEKWVKDATARKDLARFEELVSLFRQYGEKYDFPYLLLAAQAYQESRLNPNLRSRAGAVGVMQIKPSTAAASPINISDVIKTDRNVESGAKYLRYMADQYYGNEPMDQVTRGVFAIASYNAGPGMIRKLRAQAADEGYDPNRWSNNVEIIASKRIGHETVQYVGNIYKYYLAYKMITEKDAKRLAARQSAATRAGK
>NC_008536.1|WP_011686579.1|6149821_6150553_-|aquaporin-Z
MSLTRRAMAELVGTFWLVFGGCGSAVLAAAFPILGIGFLGVSLAFGLTLLTMAYAIGHISGCHLNPAVSIGLAVARRFPAHELLHYIAAQVGGGILASAILYLIASGKPGFDLSGGFAANGYGLHSPGGYALLACLVAEMVLTFMFLMIILGATDERAPVGFAPIAIGFGLTLACLIGIPVTNLSVNPARSTGPALIVGGWALEQLWLFWVAPILGAVLAGVVYPALAHRGATETVRTPRLAA
>NC_008536.1|WP_041858171.1|6150715_6151903_-|hypothetical-protein
MSAAPTDPVAGSLDNSPLARGQRVARAVATVTGTAISPLFGVCVLGAYTYAITPQPHRAALPFYCAPIFWIPLAILVTLVMLKDTVGSAAPLLKKPLDAIEILVVNKAAFLFAVLPVVWHEAAAISGWRLPGGLLPESFMAFLPTVHAAAPGAVMAGDRAIPIALTAVAGAGIAFAVWLTGHALDVLALLSPVPLLDIFFKASRAAIFLTVGAFAVFNSRVALVVSLVIIAICLLCFWWAFRLAVFGAVFAWDILRTCLLGRRRDPSLDGEVLGFTAYAIGGLSKRSFGALRIAADGSLEFAHRPVGLGFRSTVRLQRPDKYEVGKGFIFPCLLAPGKAGKNYRFQFRLLPRYAGYEEEIRDMLRLRGVRDLRVPSEFQSAWNWLRGTVARPRAT
>NC_008536.1|WP_049873211.1|6151987_6152611_-|hypothetical-protein
MLQSASPAQTTETPAEKTAKPKKAKKAATDAATTPAAAVEKTSKKSKAATESPATPAAAGEKAVKSRTPKKPAADVTAPVPAAPAAVEEKASKPRKSKKAAADVTGPAPATPAPGEAVPIPRRANRSVPEVIVPSGSANRANRSAEPPAASVSEAEIQAAKAGGMVWVNTDSGVYHKGGRWYGATKQGKFMSERDAIRAGYRAAKRE
>NC_008536.1|WP_011686582.1|6152846_6153125_+|GlsB/YeaQ/YmgE-family-stress-response-membrane-protein
MMTMIGHAFMGLIVGLVARAILPGRQHMGLILTMLLGMVGAWLGGVIGRVTGMYEEGKPAGFVMAVAGALVVLLIYVFATRSGTAILLPLTY
>NC_008536.1|WP_011686583.1|6153192_6153573_-|hypothetical-protein
MKHNTTLIVASLLSLLFLTLHITDDIVRGISKAESSNTALLVLALLLYGTLVLPERRLGHVIMLLIGLMAAAMPVLHMRGAHYGDIAKSPGGFFFVWTLWALGGLGGLTLMLSVRGLWDLRRRRPK
>NC_008536.1|WP_011686585.1|6153918_6154848_-|DUF2950-domain-containing-protein
MTRLSAFALAAAGVVLLNVPVKAATPDGRAFPSADAAAQALVDAAKSDDTAALIEILGPSARGIVTTRDSVADRNSRKVFTARAAEKMRLVASHGNPKNRTLVVGKDEWPLPIPIVERNGQWYFDTAQGREEILTRRIGSNELDAIEVCRGFVEAENQYAEKNRTANHIPIYAQMIISSPGERDGLYWDAKGEGDESPIGEIVARALAQGYTNKHEPYRGYYFKVLTAQGPSAAGGEKSYIKDGVMTRGFALIAWPANYGSTGMMTFVVDKSGIVYQKDLGPKTGEVASGYAAYDPDHTWHPVSDATRP
>NC_008536.1|WP_011686586.1|6154882_6156325_-|DUF3300-domain-containing-protein
MMTTRAISVLCVGLLIARHPYAYLQQPQPAGAPQGDSQKLLSPGQLESLVAPIALYPDPILSQVLVASTYPLEIVEAGRWLSQNSKLKDKALADAVAKQPWDASVQALVVLPDVLTRLDQNVGWTSDLGNAFLAQQNDVMDAIQRMRQRASAAGALQSTPQQTVTTTMSNNQPYIVIEPASPQVVYVPQYNPVAVWGPPPAYYPFPPIYYPPVSTGAVVAASAISFGVGMAVGAIWSGGGGWGGWGWNPGWGRGGNTVIVNNNFINNNRFNRVNVANGNRWVHNPVHRGAVPYTNRNVANRFQGGAAGAVRNPATRPTVGQTQQRLNQNGMANRGGMTGAGNANRLAPGAGGRGAIGQPGQNRPGGGGAGTPGQGNANRLAPGNAGRGAIGQPGQARPAQSRPAQPGMGNMPSRGGANRMGMPGGNPMGNRGMQGGGYRGGSGGMSRGGGMNRGGGGMSRGGGGFGGGGHRGGGGGGRRR
>NC_008536.1|WP_011686587.1|6156407_6156926_-|DUF4136-domain-containing-protein
MNRVVAIFALTCAISPVATPKARVDFCHACDFSHYQTYRWAGPPNADFLNQLMQQRVVAFVEEALSARKLKRVEKGGDLVIDFQMNVREQPVFTTFATGFGGGWDFGWGSSIATTTTEVFTLGTLTVDIVDSRGNRLVFQGVSTTPISSRPSRNTRRLARAVNEIFEKYPPR

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Crispr_ID: NC_008536_11

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_008536_11

6187291-6187379

Orphan

Consensus_repeat	Method
TGTGGGGCAGCCAATCCTGGCTG	CRISPRCasFinder

1 spacers

The CRISPR arrays of NC_008536_11

>merge|NC_008536|11|6187291-6187379|CRISPRCasFinder
TGTGGGGCAGCCAATCCTGGCTGTCGCGATGGCGCTGCGAGCCATTTAGGGGGATGAAAACCCCTTTGTGGGGCAGCCAATCGTGGCTG

>NC_008536|11|11|6187291-6187379|CRISPRCasFinder
TGTGGGGCAGCCAATCCTGGCTG	TCGCGATGGCGCTGCGAGCCATTTAGGGGGATGAAAACCCCTT
TGTGGGGCAGCCAATCGTGGCTG

Protein	Signature genes	Signature genes Name	Protein_function
NC_008536.1\|WP_011686612.1\|6187595_6190001_-\|ABC-transporter-permease	unknown	unknown	gnl\|CDD\|274576
NC_008536.1\|WP_011686616.1\|6193316_6194075_-\|CPBP-family-intramembrane-metalloprotease	unknown	unknown	gnl\|CDD\|376806
NC_008536.1\|WP_011686604.1\|6175259_6176267_+\|hypothetical-protein	unknown	unknown	unknown
NC_008536.1\|WP_157675929.1\|6178636_6179026_-\|LysM-peptidoglycan-binding-domain-containing-protein	unknown	unknown	gnl\|CDD\|236880
NC_008536.1\|WP_011686607.1\|6179331_6180483_+\|DUF3300-domain-containing-protein	unknown	unknown	gnl\|CDD\|378701
NC_008536.1\|WP_011686615.1\|6192067_6193324_+\|hypothetical-protein	unknown	unknown	unknown
NC_008536.1\|WP_011686610.1\|6182007_6184494_-\|glycoside-hydrolase-family-2-protein	unknown	unknown	gnl\|CDD\|225789
NC_008536.1\|WP_011686602.1\|6174073_6174355_-\|hypothetical-protein	unknown	unknown	unknown
NC_008536.1\|WP_011686613.1\|6190048_6191668_+\|TIR-domain-containing-protein	unknown	unknown	gnl\|CDD\|143636
NC_008536.1\|WP_011686620.1\|6197086_6198790_+\|hypothetical-protein	unknown	unknown	unknown
NC_008536.1\|WP_011686611.1\|6184517_6187160_-\|zinc-dependent-metalloprotease	unknown	unknown	gnl\|CDD\|239803
NC_008536.1\|WP_157675485.1\|6195943_6196114_-\|hypothetical-protein	unknown	unknown	unknown
NC_008536.1\|WP_011686608.1\|6180507_6181224_+\|L,D-transpeptidase	unknown	unknown	gnl\|CDD\|341130
NC_008536.1\|WP_011686605.1\|6176876_6178508_+\|DUF4091-domain-containing-protein	unknown	unknown	gnl\|CDD\|379121
NC_008536.1\|WP_011686617.1\|6194119_6195133_+\|Gfo/Idh/MocA-family-oxidoreductase	unknown	unknown	gnl\|CDD\|223745
NC_008536.1\|WP_011686614.1\|6191681_6192002_+\|hypothetical-protein	unknown	unknown	unknown
NC_008536.1\|WP_157675484.1\|6181279_6181987_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|379310
NC_008536.1\|WP_011686603.1\|6174541_6175084_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|350353
NC_008536.1\|WP_041858180.1\|6195132_6195930_+\|sugar-phosphate-isomerase/epimerase	unknown	unknown	gnl\|CDD\|224007
NC_008536.1\|WP_011686619.1\|6196244_6197087_+\|DUF4159-domain-containing-protein	unknown	unknown	gnl\|CDD\|379342

Protein	Function_ID	Function_description	E-value
NC_008536.1\|WP_011686612.1\|6187595_6190001_-\|ABC-transporter-permease	gnl\|CDD\|274576	TIGR03434, ADOP, Acidobacterial duplicated orphan permease. Members of this protein family are found, so far, only in three species of Acidobacteria, namely Acidobacteria bacterium Ellin345, Acidobacterium capsulatum ATCC 51196, and Solibacter usitatus Ellin6076, where they form large paralogous families. Each protein contains two copies of a domain called the efflux ABC transporter permease protein (pfam02687). However, unlike other members of that family (including LolC, FtsX, and MacB), genes for these proteins are essentially never found fused or adjacent to ABC transporter ATP-binding protein (pfam00005) genes. We name this family ADOP, for Acidobacterial Duplicated Orphan Permease, to reflect the restricted lineage, internal duplication, lack of associated ATP-binding cassette proteins, and permease homology. The function is unknown.	0
NC_008536.1\|WP_011686616.1\|6193316_6194075_-\|CPBP-family-intramembrane-metalloprotease	gnl\|CDD\|376806	pfam02517, Abi, CAAX protease self-immunity. Members of this family are probably proteases (after a isoprenyl group is attached to the Cys residue in the C-terminal CAAX motif of a protein to attach it to the membrane, the AAX tripeptide being removed by one of the CAAX prenyl proteases). The family contains the CAAX prenyl protease. The proteins contain a highly conserved Glu-Glu motif at the amino end of the alignment. The alignment also contains two histidine residues that may be involved in zinc binding. While they are involved in membrane anchoring of proteins in eukaryotes, little is known about their function in prokaryotes. In some known bacteriocin loci, Abi genes have been found downstream of bacteriocin structural genes where they are probably involved in self-immunity. Investigation of the bacteriocin-like loci in the Gram positive bacteria locus from Lactobacillus sakei 23K confirmed that the bacteriocin-like genes (sak23Kalphabeta) exhibited antimicrobial activity when expressed in a heterologous host and that the associated Abi gene (sak23Ki) conferred immunity against the cognate bacteriocin. Interestingly, the immunity genes from three similar systems conferred a high degree of cross-immunity against each other's bacteriocins, suggesting the recognition of a common receptor. Site-directed mutagenesis demonstrated that the conserved motifs constituting the putative proteolytic active site of the Abi proteins are essential for the immunity function of Sak23Ki - thus a new concept in self-immunity.	1.07628e-10
NC_008536.1\|WP_157675929.1\|6178636_6179026_-\|LysM-peptidoglycan-binding-domain-containing-protein	gnl\|CDD\|236880	PRK11198, PRK11198, LysM domain/BON superfamily protein; Provisional.	6.92654e-26
NC_008536.1\|WP_011686607.1\|6179331_6180483_+\|DUF3300-domain-containing-protein	gnl\|CDD\|378701	pfam11737, DUF3300, Protein of unknown function (DUF3300). This hypothetical bacterial gene product has a long hydrophobic segment and is thus likely to be a membrane protein.	2.07473e-111
NC_008536.1\|WP_011686610.1\|6182007_6184494_-\|glycoside-hydrolase-family-2-protein	gnl\|CDD\|225789	COG3250, LacZ, Beta-galactosidase/beta-glucuronidase [Carbohydrate transport and metabolism].	3.46737e-72
NC_008536.1\|WP_011686619.1\|6196244_6197087_+\|DUF4159-domain-containing-protein	gnl\|CDD\|379342	pfam13709, DUF4159, Domain of unknown function (DUF4159). Members of this family are hypothetical proteins.	1.71371e-51
NC_008536.1\|WP_011686613.1\|6190048_6191668_+\|TIR-domain-containing-protein	gnl\|CDD\|143636	cd07302, CHD, cyclase homology domain. Catalytic domains of the mononucleotidyl cyclases (MNC's), also called cyclase homology domains (CHDs), are part of the class III nucleotidyl cyclases. This class includes eukaryotic and prokaryotic adenylate cyclases (AC's) and guanylate cyclases (GC's). They seem to share a common catalytic mechanism in their requirement for two magnesium ions to bind the polyphosphate moiety of the nucleotide.	5.22389e-37
NC_008536.1\|WP_011686611.1\|6184517_6187160_-\|zinc-dependent-metalloprotease	gnl\|CDD\|239803	cd04276, ZnMc_MMP_like_2, Zinc-dependent metalloprotease; MMP_like sub-family 2. A group of bacterial metalloproteinase domains similar to matrix metalloproteinases and astacin.	3.31446e-77
NC_008536.1\|WP_011686608.1\|6180507_6181224_+\|L,D-transpeptidase	gnl\|CDD\|341130	cd16913, YkuD_like, L,D-transpeptidases/carboxypeptidases similar to Bacillus YkuD. Members of the YkuD-like family of proteins are found in a range of bacteria. The best studied member Bacillus YkuD has been shown to act as an L,D-transpeptidase that gives rise to an alternative pathway for peptidoglycan cross-linking. Another member Helicobacter pylori Csd6 functions as an L,D-carboxypeptidase and regulates helical cell shape and motility. The conserved region contains a conserved histidine and cysteine, with the cysteine thought to be an active site residue.	2.48517e-22
NC_008536.1\|WP_011686605.1\|6176876_6178508_+\|DUF4091-domain-containing-protein	gnl\|CDD\|379121	pfam13320, DUF4091, Domain of unknown function (DUF4091). This presumed domain is functionally uncharacterized. This domain family is found in bacteria, archaea and eukaryotes, and is approximately 70 amino acids in length. There is a single completely conserved residue G that may be functionally important.	2.98842e-20
NC_008536.1\|WP_011686617.1\|6194119_6195133_+\|Gfo/Idh/MocA-family-oxidoreductase	gnl\|CDD\|223745	COG0673, MviM, Predicted dehydrogenases and related proteins [General function prediction only].	1.21723e-48
NC_008536.1\|WP_157675484.1\|6181279_6181987_+\|hypothetical-protein	gnl\|CDD\|379310	pfam13645, YkuD_2, L,D-transpeptidase catalytic domain. This family is related to pfam03734.	3.01019e-93
NC_008536.1\|WP_011686603.1\|6174541_6175084_-\|hypothetical-protein	gnl\|CDD\|350353	cd14503, PTP-bact, bacterial tyrosine-protein phosphataseS similar to Neisseria NMA1982. This subfamily is composed of bacterial tyrosine-protein phosphatases similar to Neisseria meningitidis NMA1982, which displays phosphatase activity but whose biological function is still unknown.	2.24951e-29
NC_008536.1\|WP_041858180.1\|6195132_6195930_+\|sugar-phosphate-isomerase/epimerase	gnl\|CDD\|224007	COG1082, IolE, Sugar phosphate isomerases/epimerases [Carbohydrate transport and metabolism].	2.87534e-24

>NC_008536.1|WP_011686611.1|6184517_6187160_-|zinc-dependent-metalloprotease
MIRRASTTIAIVVSVFSIEAQQGPAGRPAAPPTIERRTDGMQKMDGLFPLYWDERGGNLLMEIPRMETEFLYTTGLAAGLGSNDLGLDRGQQGAGRLVSFHRVGPRVLMIQPNETFRSSSTNSAEQRSVEDSFAKSILWGFAVAAESDGRVLVDATDFVLRDGHGAANALNPGPYRVDRTRSAVFLPRTKAFPKNTEIEVTLTFANETAGGRGGLGGGPSQGPPPIGSAGAVGVGALAPGGAAAGRGGRGGGMFAGTIASVTPTAESVTLREHYSLVELPDGNFQPRYDDPRAGYGGLSFVDYSVPIGEPMVQRWIRRHRLEKKDPNAAVSEPVKPIEYWVDSGAPEDVKKALVEGASWWNQAFEAAGFRNAFKVAVLPESADPMDIRYNMINWVHRSTRGWSMGGTVADPRTGEIIKATVTLGSLRDRQDYLIFEGLLSPYATGNEKPSILYQTALARIRQLAAHEVGHTLGLGHNYYDSSAGWISVMDYPHPQEKLREDGTIDLTDAYPASIGEWDKVAINYGYRQLPHGDEPAALAKILDDAWAKDLRYMSNQDTDSNPRVDQWSNGVNQADELNRLMKVRRAALDRLGEHTIRRGAPMATIEEPLVPIFMYHRYTVESTASMVGGIDYIYAMRGDGRTAVKWETAANQRKALDALAATLKPAELTVPKQVLESIPPRPPGFGRHRELFPRTTGDGFDPLSPATVAADVTIGFTLQLDRAARMVAQHAVDSSLPGLEEVIDRFTKAIFEAQASTSYEQEVRRAEERVLVDRLTWLATAAPNGQVRAIASLKLSRLGTRLKSAVTPSEGDQAQNAMLAADIKRFLERPAETMRLIPAPDSPPGAPIGEPAMDWLAPAPLCNWSDQHPEWWSSSGWQLM
>NC_008536.1|WP_011686610.1|6182007_6184494_-|glycoside-hydrolase-family-2-protein
MNKIVAPAAVLCAILTWPAAPVRASGATAVTVSGERRQSFNQGWRFFRGDAEGAEVPGFNDAAWTAVRLPHDWAIAGPFDSKLNPHTGALPISGTGWYRKAFTLPASAAGRVFSIEFDGAMSNARVWLNGKELGSRPYGYIGFGFDLTPPLHFGAEENVLAVRLKPEERSSRWYPGAGIYRNVWLDITGPVRVARWGTYVTTPEAGTAKATVAAKTEVENRTASEVRVVLQTSLVDSRGKTVASERREAAIAAGGAQTIDANLAVARPRLWDTESPYLYTVVSEVMEGRRVLDRYETPVGIRAIAFDKNKGFQLNGRSMKLQGVCLHHDLGALGAAVNRRAIERQLEIMKGAGVNAIRTSHNPPAPELLELADRMGLLVIDEAFDMWRIPKVPNGYAKYFDEWSERDIRDMVRRDRNHPSVILWSIGNEVGEQGRPDGWQVAKRLVDVVHAEDRTRPTTAAFDNWVGAIKNRVAEQVEVQGFNYKPNHYEEILKGHPDWMILATESSSTVSSRGIYHVPLENYPKHASLQITSYDVMAPAWATLPDVEFSYQDKLPNVLGEFVWTGFDYIGEPTPFFGGRSSADDWPARSSYFGMVDLAGFPKDRYYLYQSVWTTKPMVHVLPHWNWQGREGEKIPVMVYSNGDEVELILNGKSLGRKRRFGEAVELPVGGNVSADKKFVSKYRLTWEVPYAAGTLRAVSYRGGKQVAVDEVRTAGAPARLRLIADRSTIHGDGDDLAFVTVRIEDKDGNLCPGADNLIRFQVTGAGGIRAVDNGNAASTEPFQAEYRKAFSGLALLIVEGAKAGKIQVAATAEGLVAGVTEITAIAP
>NC_008536.1|WP_157675484.1|6181279_6181987_+|hypothetical-protein
MEFLPQRSPPLEVCNLLFPKRLALVVLFSFPAAAVAPSTTQLASLLKLAPRLAPQALEAALTALQRLQATGAKVRSDVVTVIDYTKPSTERRLWVFDLAHTRVLFQELAAHGKNSGDNQAVRFSNARNSLMTSIGAFLTGETYIGQHGLSLRLQGLEKGVNDNSMDRALVIHAAAYVSDALAKARGRIGRSWGCPAVRPEISRSLIQTVQGGSLVLAYYPDKTWLQTSKLVGVTP
>NC_008536.1|WP_011686608.1|6180507_6181224_+|L,D-transpeptidase
MRPIALALLLGRLCLAAHAAGTIACHLESASPLSRFKTGQLALLEKLNHADRPHLARLSRILVPNRWDPDELHYSPMPREVPELSDRNKALIVDLAAQVFGAYESGRLVRWGPVSTGDRRHQTPSGTYHLNWHARVRVSSENPTWIMPWYFNFSSDRGLGLHQYALPGRPASHGCTRLLATDAQWIFNWGEGWSTDGDTGEPSETGTLVLIVGKYDFKAPQPWLQPRWWSQGVSLSLP
>NC_008536.1|WP_011686607.1|6179331_6180483_+|DUF3300-domain-containing-protein
MRATRATTILCVAILIAPHTFTFAQQQPQITEAQDQSQQSLTPGQLDSLIAPIALYPDPILSQVLVASTYPLEIVEAARWLKEHSTLKGKELTDAAATQTWDASVQTLVMLPDVLSRLNQDVSWTSELGNAFLAQQQDVMDAIQRLRQKASAAGALQSTPQQTVTTTTANDQPVIVIEPANPEVVYVPQYDPAVIWGPAPDYYPYPSLYYPTGDLSFGAGMAVGAIWGGGWNNWGWGFGWGHNNVVVNNNFINNNRFNRVNVANGNSWIHNPAHRAGVPYADRNIANRYQGVAAHPVARPTVGQTEQRLDKIPSQGGAARISPGNIGQGGGDRIGNRSVERPAASPGAFGGMDQGGARTMMNSNRGSASRGGGGAVRGGGRRR
>NC_008536.1|WP_157675929.1|6178636_6179026_-|LysM-peptidoglycan-binding-domain-containing-protein
MQQLGVQVQNVNMEGNKLLIRGVAPSADIKNRIWDQVKLIDASYSDLTCDLSVSQAASQQPGATMTAGAAAGGGQNQRHYTVKSGDTLSKISREFYGDANQYTKIFNANRNILRDPNTIKPGQELIIPE
>NC_008536.1|WP_011686605.1|6176876_6178508_+|DUF4091-domain-containing-protein
MTFSGKSLSSALLVFSTAFSALSMAETNPGNPAVWTAPSMQRVGMTDPAGSVSDVSLAAARGEYESFQIVANGASKGLGNVNLTVSDLEGPDGKVIPHGNFTLYREKYMHVTSPSPNWKGSNQPMGAGWYPDALIPFTDPDTGKPLSGAKISAVPFDVKAGNNQPVWVDLLVPQTAQAGTYKGTYTVTSNEGTFTGNISLKVWNFALPAAPTLKTSFLFFQAGTLAAQRELLRNKISPLSTNPADQPLLMKEHGLSATQTGPFSGADVGRCAMSPAPSVSQFKTVAAQQQPGLLLYDYSADEIGHCTQLYPTIRQWANNMHQAGIKNLISMSPTPALYNDGSGTGRSAVDIWVLLPVMYNNSKTQVGEVLKKGDSVWSYNTLVQDAYSPKWLIDFSPVDFRIQPGFISQSLNLTGMLYWRVDKWPSNAWDNVNNAGTYSSSNYPGEGMLVYPGGPVGVKGVVASMRMKWLRDGVEDYDYVQILKDLGKGDMAMQISRSVGPDWTNWTRDSKAIENARLKLGEAIDQIMNTTPTTATGTRAAGN
>NC_008536.1|WP_011686604.1|6175259_6176267_+|hypothetical-protein
MTQASKALAASTFLVLGFLAVYTPAKSGKPPKVDPKQSGAVMWRAPEDVASRSLFYGPGGKGHEPHGTFTFDKEDMSGTNPKFDIVDQDGVKWRVKMGQEAGPETVASRLVWSVGYFANEDYFMPVLHVQNMQRLRRGRNFVSADGTVHNVRLKRHLKDEKKVGTWSWANSPFTGTREWYGLRVLMAVMNNWDLKDINNSVYQTHDSPPEERYVVSDLGASFGTTGLNWMLKGDPAAYCSSKWIKNTSGEFVDFNVPSPPAMNYYIDFPEMARRLSLLWIGRHIPRTDARWMGDQLAKLSPAQIRDAFRAGGYSPADVERLSVVLERRISELKKL
>NC_008536.1|WP_011686603.1|6174541_6175084_-|hypothetical-protein
MNFFKNRRILAALVLCCSILTWQALAETPAIAIPIPNFHQVNEHVYRGGQPSPETWEHLAKIGVKTVIDLRREGEEEHSVAQEAEAVKKAGMTYVNVPMKGVVAPTDDQIAKVMALLNTNEPVFVHCKRGSDRTGAVIACYRISHDRWQQKQALQEAKSHGMALFQVGLKRYIMTYQPSM
>NC_008536.1|WP_011686602.1|6174073_6174355_-|hypothetical-protein
MMQSAVSRNMTHHQITLVEQALRQLTRVEPTSWDEIPLDLQLSFTKYMCRDVWTGQCDLLSLREAALMILRDAIMRTGEFGDQEELCGGLPAM
>NC_008536.1|WP_011686612.1|6187595_6190001_-|ABC-transporter-permease
MSVLQDTRIALRLLARAPATTAIALVSIALSTGAAGVVFAAIKAVLLNPLPYARAEELVQLRSEYPRMQQQSTGDWVFWDDAQEVIRRTRTLESVGVYRNALFELGGDPSSPPEALYGLLITPNLFSTLGAAPMLGRNILPEEAGPGHAQVMILSYGLWARRFHADPRIVGRTVTVNAHECLVVGVMAPEFNFPMRRSAAHTPSPYVEFWAPLVVRAGARLGGLGAVGRLRPGISAAEARQDIAAIGDALAREFPATNRDRTLQLNLLRDQTVGNARGALWLLMGATLLFVLIGCSNVANLLLARATARRNEFAVRMAVGAGRGRIVRQLLTESCVLALVGGAGGFALAAAAWKALPALAPVSIPRLAAARADSTVFCFSLAMGMVSGILFGMAPALRLASGGLGVRGAAATRDRLRPVLVAMEVALSVVLVVIGGQLLGSFRRLVAADPGFQADHVLASVVLPSPERYRDPERRGLFYRRILDSVRAIPGVEGAGTVDALPFSGENHGGFVLGSQSAQPLTAEIDVAGGEYLQTMGIRLVEGRWFREEEMNASNDAAIVNTLVAGRLWPGARAIGQRICLYCTPENPNNWKRVVGVVASARHASLNEAEAGNVYVAAGAMQTAQFLVVRTSRPAGEIGTAIRRAIAAIDANQTVFLTASMQDLIGDSVADRRFITMLLAITGCLALLLAAAGVYGVIAYSTSRRTQEIGIRMAVGATPGNVFALIFRQGFAAVAMGLALGLGAAVAALRLLRSVLPGLESGQSAYVCAAVSLVTLMAATACWLPARRATRTDPLEALRQE
>NC_008536.1|WP_011686613.1|6190048_6191668_+|TIR-domain-containing-protein
MATSDLLPREDLLALLETAGQLATEADQARLADAILDRACQMTGSPDGSVLLFDNERGGLFFAAAKGEKGPSLLEAWGEYSSQRVPVSGSKAGLVYTTGETIVEQRLDDDTDHFKGVDEQTRRTSQSMVCAPLETGGSRIGAIQILNKPEPYSDRDLALLKQFAVQAAAAIKNARRLRELAAHMGLYTRELGGDLLGLLSQTARREDTTVMFADMRGFTQVCQSQEDPAHTQAIVNDLLTMLAEQVLTHGGVVNKFLGDAVLAFFRKENGPKQAVRCAFGMLERFESLRQRWGESSNQDLEYLDLGIGIATDRVALGAFGSASVRDFTAIGTAVNRAAAFEHAARDGRRVLVDRRTWDAAREIIADHAEPERFELRKPGQGSGVVYWQYHLKRLKPDLVVRIFISHSHLDRVYVEREVTHNLKQFGIETWYSNTDLIPGENYINTIQAGLLKSDWFVVVVSARSVASDWVRAEVRTAFQDSRLRNRIIPVVIDDTSPGLIHHDLATVHAVYAKDGNGAGHAIYEALRARTHQLESGAVA
>NC_008536.1|WP_011686614.1|6191681_6192002_+|hypothetical-protein
MKAAALLVILAILTAIVAGAQCVVACAQPASLPPCHHTPQKAAKTCDSSLVFDERRPVTVIDAPSAGPVASHRTFQPPAHPGRVIAAAAGLRLHPPGASAPFVLRI
>NC_008536.1|WP_011686615.1|6192067_6193324_+|hypothetical-protein
MHRKLLLLSVLCATAFAQMPPMPNMPGMSGMSHMNMNRAGMYLMNMSSGTAMNPYSWQMPMKMTEAGTWNLMFMSQVFLVDTQQSGPRGADKFYSANWFMASGIHKVGRGSLMLTAMLSLEPATITNRSYPLLFQTGETAFGRPLVDRQHPHDFIMSLSADFAYPLNRDTMLQLYYAPVGDPALGPVAFPHRASAFELPQATLGHHWQDSTHIANNVATVAVRHKWLRVEASGFYGSEPDENRWNIDWGPMNSWAARLSAAPTQNWLAQVSTGHLVKPERQEEGDVQRTTASLQYSRPMDSGTSWSTSLIWGRNHELLTHRNVDGYLLETLYPVTRRNFLTGRIEVVDKDELALPKGLGTTFRIRSFIAGYTRDIVTFHGIETGIGANVTAYGIPPVIAPYYGDHPWGVNVYLRMRLR
>NC_008536.1|WP_011686616.1|6193316_6194075_-|CPBP-family-intramembrane-metalloprotease
MPPGATTDRLLRIYLWLAFGITWGMGGLALLGGEIGPGRPTPLHPLYYAAAFGPSIAGVLMAGATEGRAGVRRLLARVVPRGSSVPWYGAVLVGFPALNLVAARLLAPGFLAHLPEWHRLLILLPVTLVTDTGPLGEEFGWRGFFLPRLLQRRLPLAAALITGVIWWAWHLPTFFIPALSQHRLSIAVFLVNSVALSVIMTWLYQRTRGDLLLMILVHLAANYCGAIGVPFSAEVGVEVACAAVILACGGLT
>NC_008536.1|WP_011686617.1|6194119_6195133_+|Gfo/Idh/MocA-family-oxidoreductase
MPMKIAVLGLGFMGSVHLRALRDIEGAELAAVFSNDERQLSGDLSATQGNIGGPAGHFDFSAIKRYRELADVFADPDIEAVDLCLPTHFHESATVQALRAGKHVLVEKPMALDGPAARRMVAEAGRSGRILMAAQVIRFFPEYVALRDSLPRLGRVRSAFFRRRCAAPAWGGWLKDPAKSGGGVFDLLIHDLDFCLHLFGAPQAIDATGNCDPASGIDLIDARLYYPFGAVTVAGGWQKSGAYPFGMEYSVTGEHGAMEFHSAGRPPTLYAEDAEPLHLEVCDGYAAEIAYFIECCRANRKPDRCPPEESAYVVELMRELLAARERNGEKISCSNQE
>NC_008536.1|WP_041858180.1|6195132_6195930_+|sugar-phosphate-isomerase/epimerase
MFWAERDDLAVIAALGVRYGQLGVPGGMKLDSAGAAHWKQALSSAGITPVTVVAAYEGEDYADIPTVQHTVGFIPPATRAAREARTLAVSDFAAALGVRSIACHIGFVPEDAHDPGYTGVRDTVRHVCDHAARHGQTFALETGQERAGVLLDFIHDVDRPNLRINFDPANLILYGTDEPLAALKTLAPLVVSVHCKDGDPPPAGIPGALGSERPLGHGSVGIPRFIQTLREVGFPGPLNVEREAEDQSQRLRDIAAGIALLRTLV
>NC_008536.1|WP_157675485.1|6195943_6196114_-|hypothetical-protein
MSDEAKFGSEPECAVCYAAHDAEIHEATLRIHRWFCGQVTHHFEEDVLTVAELVAS
>NC_008536.1|WP_011686619.1|6196244_6197087_+|DUF4159-domain-containing-protein
MTFRFPLGLAASAVAFGTLFAFQSPFREFPGVEYRVGDIALPTDYSEKTEWTFARLMYPPAPRGRFGRGYGFRGGGVWTEGNTMWTQDYPRADRHFAMAVRRLTRIHVRSVEQPVNLDEGGEFDWPWLYAVQTGTWQLTDSQARSLREFLLRGGFFMADDFWGPGEWETFMASMKKVFPEREVVELQNPDAIFHTVYDLDDRYQVASQGSVRRGTSWKCDGCPDHWRGIYDDHGRLMVAITFQSDVGDSWEWADAPDYPERYAALGIRIGVNYIIYAMSH
>NC_008536.1|WP_011686620.1|6197086_6198790_+|hypothetical-protein
MYARAAAFLFAIRCLSAQPWASFANGPQHNALSPAKSQSLTQIRWHTPVDLQPQYEGSELLIHYGSPLVTALNTVIVPVKTGVDGNFRVEARTAADGALKWSLASDYVLPSHDWTPVFGPVLTPSGRLYYPGAGGTVYFRDLPDSSSGPQGQIAFYGMASFSANVIINTPLTADSAGNIYFGFLVTGPTPIPLSNGVARIDANGQGSWAPVAGAVSTNCAPALSRDRKLLYIAVNNMGSGSLVALDSATLTPVARVALKDPVSGSDSLLDDNASSSPTVGPDGDVYYGVLENPVGENHLRGWLLHFDSLLSQSKLPGAFGWDITASVVPSSMVPSYSGQSAYLLMTKYNDYAEAGGAGLNRLAILDPNTAGVDPVTGTAVMREVLTVAGVTPDGPAPSVKEWCINSAVVDPATHSIVAGNEDGKLYRWDLASNTLSQTLVLTPGLGEAYTPTLVGPDGMVYAINNATLFAVGDTAPTVSTSPDSLAFSYQVGQASPAAQTLHVMSSPAGLPVSVTATCSWLVPSPAVGVTPFDSVISLNLAGLGPGTYACSLTVMGPSGAQARVRIR

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Crispr_ID: NC_008536_12

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_008536_12

6677272-6677404

Orphan

Consensus_repeat	Method
GCGAATATTCCGGTGCGGATGTTTGCGGTCTGCGAGCAA	CRISPRCasFinder

1 spacers

The CRISPR arrays of NC_008536_12

>merge|NC_008536|12|6677272-6677404|CRISPRCasFinder
GCGAATATTCCGGTGCGGATGTTTGCGGTCTGCGAGCAATCAAGAGGAGTGTAGTACAGTGCGGCAAGCCGCAAATTGAAATGGTGGTTTACACGCGAATATTCCGGTGCGGATGTTTGCGGTCTGCGAGCAA

>NC_008536|12|12|6677272-6677404|CRISPRCasFinder
GCGAATATTCCGGTGCGGATGTTTGCGGTCTGCGAGCAA	TCAAGAGGAGTGTAGTACAGTGCGGCAAGCCGCAAATTGAAATGGTGGTTTACAC
GCGAATATTCCGGTGCGGATGTTTGCGGTCTGCGAGCAA

Protein	Signature genes	Signature genes Name	Protein_function
NC_008536.1\|WP_011687014.1\|6671128_6672301_-\|L-rhamnonate-dehydratase	unknown	unknown	gnl\|CDD\|239443
NC_008536.1\|WP_011687025.1\|6686604_6687471_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|274618
NC_008536.1\|WP_157675515.1\|6674893_6675922_-\|TIM-barrel-protein	unknown	unknown	gnl\|CDD\|366542
NC_008536.1\|WP_041858243.1\|6669388_6669985_-\|hypothetical-protein	unknown	unknown	unknown
NC_008536.1\|WP_011687021.1\|6680045_6681449_-\|glucuronate-isomerase	unknown	unknown	gnl\|CDD\|376859
NC_008536.1\|WP_011687020.1\|6678438_6678945_-\|NUDIX-hydrolase	unknown	unknown	gnl\|CDD\|239217
NC_008536.1\|WP_157675517.1\|6687503_6688430_-\|tetratricopeptide-repeat-protein	unknown	unknown	gnl\|CDD\|315987
NC_008536.1\|WP_011687023.1\|6683465_6685409_+\|prolyl-oligopeptidase-family-serine-peptidase	unknown	unknown	gnl\|CDD\|226584
NC_008536.1\|WP_083783863.1\|6685344_6686601_+\|amidase	unknown	unknown	gnl\|CDD\|223232
NC_008536.1\|WP_011687013.1\|6670130_6671123_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|226324
NC_008536.1\|WP_157675516.1\|6677422_6678502_-\|flippase-like-domain-containing-protein	unknown	unknown	gnl\|CDD\|377103
NC_008536.1\|WP_011687022.1\|6681519_6683466_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|273828
NC_008536.1\|WP_011687018.1\|6676061_6676721_-\|hypothetical-protein	unknown	unknown	unknown
NC_008536.1\|WP_157675514.1\|6669981_6670131_-\|hypothetical-protein	unknown	unknown	unknown
NC_008536.1\|WP_011685667.1\|6667828_6668974_-\|IS110-family-transposase	unknown	unknown	gnl\|CDD\|226077
NC_008536.1\|WP_011687016.1\|6673536_6674883_-\|Gfo/Idh/MocA-family-oxidoreductase	unknown	unknown	gnl\|CDD\|223745
NC_008536.1\|WP_157675939.1\|6672297_6673512_-\|MFS-transporter	unknown	unknown	gnl\|CDD\|340877
NC_008536.1\|WP_041858246.1\|6679718_6679946_+\|hypothetical-protein	unknown	unknown	unknown
NC_008536.1\|WP_041858245.1\|6678976_6679597_-\|hypothetical-protein	unknown	unknown	unknown
NC_008536.1\|WP_041858242.1\|6669048_6669396_-\|hypothetical-protein	unknown	unknown	unknown

Protein	Function_ID	Function_description	E-value
NC_008536.1\|WP_011687014.1\|6671128_6672301_-\|L-rhamnonate-dehydratase	gnl\|CDD\|239443	cd03327, MR_like_2, Mandelate racemase (MR)-like subfamily of the enolase superfamily, subgroup 2. Enzymes of this subgroup share three conserved carboxylate ligands for the essential divalent metal ion (usually Mg2+), two aspartates and a glutamate, and conserved catalytic residues, a Lys-X-Lys motif and a conserved histidine-aspartate dyad. This subgroup's function is unknown.	0
NC_008536.1\|WP_157675515.1\|6674893_6675922_-\|TIM-barrel-protein	gnl\|CDD\|366542	pfam01261, AP_endonuc_2, Xylose isomerase-like TIM barrel. This TIM alpha/beta barrel structure is found in xylose isomerase and in endonuclease IV (EC:3.1.21.2). This domain is also found in the N termini of bacterial myo-inositol catabolism proteins. These are involved in the myo-inositol catabolism pathway, and is required for growth on myo-inositol in Rhizobium leguminosarum bv. viciae.	3.41672e-11
NC_008536.1\|WP_011687021.1\|6680045_6681449_-\|glucuronate-isomerase	gnl\|CDD\|376859	pfam02614, UxaC, Glucuronate isomerase. This is a family of Glucuronate isomerases also known as D-glucuronate isomerase, uronic isomerase, uronate isomerase, or uronic acid isomerase, EC:5.3.1.12. This enzyme catalyzes the reactions: D-glucuronate <=> D-fructuronate and D-galacturonate <=> D-tagaturonate. It is not however clear where the experimental evidence for this functional assignment came from and thus this family has no literature reference.	0
NC_008536.1\|WP_011687020.1\|6678438_6678945_-\|NUDIX-hydrolase	gnl\|CDD\|239217	cd02883, Nudix_Hydrolase, Nudix hydrolase is a superfamily of enzymes found in all three kingdoms of life, and it catalyzes the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes belonging to this superfamily require a divalent cation, such as Mg2+ or Mn2+ for their activity. Members of this family are recognized by a highly conserved 23-residue nudix motif (GX5EX7REUXEEXGU, where U = I, L or V), which forms a structural motif that functions as a metal binding and catalytic site. Substrates of nudix hydrolase include intact and oxidatively damaged nucleoside triphosphates, dinucleoside polyphosphates, nucleotide-sugars and dinucleotide enzymes. These substrates are metabolites or cell signaling molecules that require regulation during different stages of the cell cycle or during periods of stress. In general, the role of the nudix hydrolase is to sanitize the nucleotide pools and to maintain cell viability, thereby serving as surveillance and "house-cleaning" enzymes. Substrate specificity is used to define child families within the superfamily. Differences in substrate specificity are determined by the N-terminal extension or by residues in variable loop regions. Mechanistically, substrate hydrolysis occurs by a nucleophilic substitution reaction, with variation in the numbers and roles of divalent cations required. This superfamily consists of at least nine families: IPP (isopentenyl diphosphate) isomerase, ADP ribose pyrophosphatase, mutT pyrophosphohydrolase, coenzyme-A pyrophosphatase, MTH1-7,8-dihydro-8-oxoguanine-triphosphatase, diadenosine tetraphosphate hydrolase, NADH pyrophosphatase, GDP-mannose hydrolase and the c-terminal portion of the mutY adenine glycosylase.	3.3936e-11
NC_008536.1\|WP_157675517.1\|6687503_6688430_-\|tetratricopeptide-repeat-protein	gnl\|CDD\|315987	pfam13424, TPR_12, Tetratricopeptide repeat.	1.0183e-06
NC_008536.1\|WP_011687023.1\|6683465_6685409_+\|prolyl-oligopeptidase-family-serine-peptidase	gnl\|CDD\|226584	COG4099, COG4099, Predicted peptidase [General function prediction only].	0.000181236
NC_008536.1\|WP_083783863.1\|6685344_6686601_+\|amidase	gnl\|CDD\|223232	COG0154, GatA, Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidases [Translation, ribosomal structure and biogenesis].	6.52557e-81
NC_008536.1\|WP_011687013.1\|6670130_6671123_-\|hypothetical-protein	gnl\|CDD\|226324	COG3802, GguC, Uncharacterized protein conserved in bacteria [Function unknown].	1.32602e-124
NC_008536.1\|WP_157675516.1\|6677422_6678502_-\|flippase-like-domain-containing-protein	gnl\|CDD\|377103	pfam03706, LPG_synthase_TM, Lysylphosphatidylglycerol synthase TM region. LPG_synthase_TM is the N-terminal region of this family of bacterial phosphatidylglycerol lysyltransferases. The function of the family is to add lysyl groups to membrane lipids, and this region is the transmembrane domain of 7xTMs. In order to counteract attack by membrane-damaging external cationic antimicrobial molecules - from host immune systems, bacteriocins, defencins, etc - bacteria modify their anionic membrane phosphatidylglycerol with positively-charged L-lysine; this results in repulsion of the foreign cationic peptides.	1.23681e-35
NC_008536.1\|WP_011687022.1\|6681519_6683466_+\|hypothetical-protein	gnl\|CDD\|273828	TIGR01840, poly3-hydroxybutyrate_depolymerase_A_precursor, esterase, PHB depolymerase family. This model describes a subfamily among lipases of the ab-hydrolase family. This subfamily includes bacterial depolymerases for poly(3-hydroxybutyrate) (PHB) and related polyhydroxyalkanoates (PHA), as well as acetyl xylan esterases, feruloyl esterases, and others from fungi. [Fatty acid and phospholipid metabolism, Degradation].	3.10617e-05
NC_008536.1\|WP_011685667.1\|6667828_6668974_-\|IS110-family-transposase	gnl\|CDD\|226077	COG3547, COG3547, Transposase and inactivated derivatives [DNA replication, recombination, and repair].	1.80957e-23
NC_008536.1\|WP_011687016.1\|6673536_6674883_-\|Gfo/Idh/MocA-family-oxidoreductase	gnl\|CDD\|223745	COG0673, MviM, Predicted dehydrogenases and related proteins [General function prediction only].	3.04321e-47
NC_008536.1\|WP_157675939.1\|6672297_6673512_-\|MFS-transporter	gnl\|CDD\|340877	cd17319, MFS_ExuT_GudP_like, Hexuronate transporter, Glucarate transporter, and similar transporters of the Major Facilitator Superfamily. This family is composed of predominantly bacterial transporters for hexuronate (ExuT), glucarate (GudP), galactarate (GarP), and galactonate (DgoT). They mediate the uptake of these compounds into the cell. They belong to the Major Facilitator Superfamily (MFS) of membrane transport proteins, which are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	2.37797e-81
NC_008536.1\|WP_011687025.1\|6686604_6687471_+\|hypothetical-protein	gnl\|CDD\|274618	TIGR03508, decahem_SO, decaheme c-type cytochrome, DmsE family. Members of this family are small, decaheme c-type cytochromes, related DmsE of Shewanella oneidensis MR-1, which has been shown to be part of an anaerobic dimethyl sulfoxide reductase.	5.80624e-06

>NC_008536.1|WP_011687018.1|6676061_6676721_-|hypothetical-protein
MISQKRSQAARINGAKSRGPVTAEGKAISARNAMRHGFLAKTVVLCNEDAKTFEALFYLLIQRFSPVDDIEMSAIEEMAAAHWRMRRVMNMEHALLDSVIRENLDNEVPGEQTLAAFTDPSTQATLALLQRYEARFQNMYHRALRSLVVLRKLPARTAEPNEPKTPNLCNTELPEPTPIRPPEPAEPSAEQPAEYTDPLILPLVSADPECLPFNPDIFL
>NC_008536.1|WP_157675515.1|6674893_6675922_-|TIM-barrel-protein
MTRRTLLGLAAAAPFAAAEPPPPVKLGIDLFSLRSQNWTPFQLLEYSAAQKAKVVHFSEIRFIGSLEPDNLRAVRRRAEELGIQVEIGMKSICPTSKMFDAKAGTAEEQIARMLDAAKLVGSPIVRAVLGSSEDRKPGPLEKHIESTVQVLRNVRSRVQDANLKIAIENHSGDMQGHELKQLIEAAGREFVGACLDSGNPAWTLEDPHVTLDALYPYVLTSHVRDSAVWKVPEGIAVAWVRMGEGNVDIDSYCRKYAELCPGRALSLESIVTGPRLFATRDPKFWDAYRDIPAWDYERFLQVAERGQPRPAPPRAADAEAGKRREREDLEASADHTRKLLGL
>NC_008536.1|WP_011687016.1|6673536_6674883_-|Gfo/Idh/MocA-family-oxidoreductase
MNRRQFIRAGTAGLGAAALGFAQAGSTKTPRVGLIGTGWYGKADLFRLLQVAPVEVVSLCDVDRRMLSEAADMTAERQKSKKRPRTFADFRQMLAEKDLDIVLIATPDHWHALPMIAAVKAGAHVYCQKPISVDVVEGQAMLAAARKYNRVVQIGTQRRSTPHLMEAREQIVRAGKLGKVGLVEIYCYYHMRAENNPPDTAPPAELDYNMWTGPAPMRPYNSLVHPRGWRAFMEYGNGIVGDMCVHMLDMVRWMMDLGWPRSVESTGGILVQKGSKANISDTQLATFDYGDVKIVWQHRSWGDAPDEKYPWAATLYGDKGTLKAGVMGYDFTPSVRGEKPVHKDVTYELEQYPEDKTEKDLERHVAPAIRGHMKDLLNAIATNGRPVADIEQGHISTSSCILANIAMNLGRTLKWDAAQQRVVGDEEANRLLRRPYREPWVHPTPESV
>NC_008536.1|WP_157675939.1|6672297_6673512_-|MFS-transporter
MRWSIAILVSAAIAVSYFDRQTLPVAIAAIQRDIPVSNTQFSYLQGAFLLAYAGMYAGGGKLIDVLGTRRGFLWIMIWWSLACASHGLAASFGMLAASRFLLGMGEGGGFPAATKAVSEWFPAHERSTAMGIINAGSAVGAVMAPPGIAFVIATWNWRWVFLLSGAVGMLWTLWWSRTYFVPPRAAQTEASSDISWSRLFTYRQVWGLVTAKFLSDAAWYFYIFWLPKYLYDVRGFDTKQVGYFAWIPYAASGVGSLCGGWFSSHLLRSGCSLDRSRKIALGASAGLMPLIFFVTQAPVQVAILLFSIAFFGQQSWSTLVMILPADLFPHEVVGSVAGLVGFGGAMGGFVFGLVVGYLLDHGFGYGTVFPMVSTMHVIAFGVILLTVRKVAPLAAFREKIEKRP
>NC_008536.1|WP_011687014.1|6671128_6672301_-|L-rhamnonate-dehydratase
MKITEIRTRVVEWRGKTVPPQPHFCTNPMDILDLPADSMGSFRFHGWLIVEVFTDAGIVGIGNAALSPRVTKQLIDVYLKPLLLGKDPFDYEFLWQHMYRQTMAFGRKGVAMVAISALDIAIWDILGKAAKQPVFKLLGGRTKQKIPVYASRLYSQPLDQLAAEAKLYKDQGYRAMKLRFGWGPVDGAAGMQRNVELVRTVREVVGSEIDVMADAYMGWTLDYARRMLPLLESFHLRWLEEPVIPDDIHGYAALKALGRIPIAGGEHEHTSYGFRELLEAKAVDYIQFDTNRVGGITQARKVQSLAEAFSVPVVPHAGQMHNFHVVMASLNSPMAEFFPVVDVEIGNELFWYIFEGEPTPMDGYIDLRDDVPGLGLTIKEDALGQFAIIE
>NC_008536.1|WP_011687013.1|6670130_6671123_-|hypothetical-protein
MRLIQLHGPEGRRVGIVDGDFIRLLNEARSIYALARSAVSAGTPLAKAADADAGIEVASYDEIYSGRSRWRILPCIDHPLESARCMVSGTGLSHMRSADNRQAMHAAGEQVTDSMRMYQSGVEGGRPAPGQVGVSPEWFYKGTGAILRAHGEPLDIPVYAEDGGEEPEIAGIYLIDQAGAPRRIGMAAGNEFSDHLFEKKNYLYLASSKLRTCAIGPELVSAPEFDLVRGEVAIERGGAVIWRKAIQSGERAMCHSLANMEHHHFKFEAHRRPGDVHIHFFGADAFSFGEGIRLADGDIMQVQWDGFGRPLRNPVRVIAGSETPVVVKDI
>NC_008536.1|WP_157675514.1|6669981_6670131_-|hypothetical-protein
MRSLLLGLLLAASERSALLNPEDFRPDRELVAEGRWLPRRLHRLLAALR
>NC_008536.1|WP_041858243.1|6669388_6669985_-|hypothetical-protein
MKAADWSGTTINSATGPLTRPTIVLRKDYAAWEGEKLTPAGLFWQRDVSDGMESSISGGRKVQNLSPAINSYMYANARAIAAIARSSSEQIGYTPWYFEMPEKGRGYEVAWKQLMDPQGFYAPYGLTTAERRHPEFQIADKGDDCQWNHQHHAARARQRAQRLSAGRRLRARLAPGLRYLHQEPAPQTRERRGSPAGG
>NC_008536.1|WP_041858242.1|6669048_6669396_-|hypothetical-protein
MDENLNRLTGVWWARELKLRKKTYYGRGDHYNHSSYADLAITGYIGLRPRADDVVEVKWFALDRVPCHGHDLGIVWDKTGDHFREGQGLRVFSDGREIAHSPTLAGTTGRLSEMV
>NC_008536.1|WP_011685667.1|6667828_6668974_-|IS110-family-transposase
MKKNSIARLQVTKSQIRRMAAKQRLTVGLDLGDRSSRYCILDEAGEKASEDQLPTSKAGLDMLFAKMAPCRIALEVGTHSPWVSRHLAAMGHEVIVANPRKVRLITQSVKKNDRMDAEQLARLARVDPKLLAPIRHRGPEAQADLAVIRARAELVEGRTKLINAARGLTKPMGERLKSCDADTVKESMADGLSEATQKVIRPLLKSVEVITQQIKVYDQQIQEIEKRYPETKLLKQVHGVGPLVSLAFILTLEDAERFEHSRDVGPYLGLTRKQRESGESAPELGISKAGDELVRRLLVQAAHCILREDAPDSDLKAWGLTKVGAGAGKKGSKSRKKKAVVAVARKLAVLLHHLWVTGEVYDPQYNRKAIEASKRTKQAAA
>NC_008536.1|WP_157675516.1|6677422_6678502_-|flippase-like-domain-containing-protein
MASRLSAGPDRGPGALPEAVLTPGAPEAQTLEGAAAEPAKPSRAWYWILAGGLAAVLLYYSLRGVEWGRVWQSILGARWQYLAIGTAVSVINYFVRSLRWRVLLNARGHFPVGTVFWATMAGYMANNFLPARAGEVVRSFIISDRSGLSRTYVLTTALTERLMDAIALVLCGSVVLLQVRPKPAWMDQVGRTTAIIAALGALTVAVLPHAEGLIEKLLHRIPLPAGIRARLLGLAEQILLGLRAFHNAGRLLSFAALTALIWLSDAGVMMISSRAFDIHMTFPVAMLLLAGMGLGSALPATPGYVGIYQFAAVTILPPFGIDRNAALAFIFVAQALGYAVVLALGLLGLYPIKQASRAS
>NC_008536.1|WP_011687020.1|6678438_6678945_-|NUDIX-hydrolase
MTEEIYREAFATLDAWVGEPKDGLPEEFFLFLSRYTPLVNVDLWIRDEDGRTLLTWRQDETYGAGWHIPGGIIRYRETAEHRIRATARRELGADVTFDAEPMAIEQAMDPRQRERGHFISLVYRCRLVGPPDPALQYVAGTPKRDQWAWHRGCPRDLIEAQAHYRRLF
>NC_008536.1|WP_041858245.1|6678976_6679597_-|hypothetical-protein
MSPAKTTLGATVWDLPPLILHPFNEKVPPTALLENSKAALMLSGLIPTDGADHDDLKRRLLAGRYSEMRMLFFLGKDVFRWLDQCVEWAQRIPELSGCDIQPQSFAGLLTASPPEAVKEKLVRWGVADYASIFARSIGINSVFAEPPTFATLTENFLRNYHRYGDFLYRCYMDSQAHEPLGPENFQFALYASGEYSRLLENQWEAQ
>NC_008536.1|WP_041858246.1|6679718_6679946_+|hypothetical-protein
MRSLRELITGDRGQDLAEYCLLTALVALIGLAVLIHVSGGMQALWTGANTSLVAGNSAVSAGTSGASATTSAPAH
>NC_008536.1|WP_011687021.1|6680045_6681449_-|glucuronate-isomerase
MSFIHDDFLLSSKTARRFYHTFAEDQPILDYHCHLPPQDVAANRQFKDLFEIWLEGDHYKWRAMRANGVPESHCTGNAPAYEKFMAWAKTVPATLRNPLYHWTHLELKRYFGIDELLNEQSAARVWEQANAVLATPELTAHRILEKFHVKAVCTTDDPTDDLAAHQAIAASGLATKVFPTFRPDKALHVHAPELFNPWVDRLQVAADTHISTMAEFLDAIKKRHDFFHAMGGRLSDHGINHAFSDFPSEHEAARIFGRARCGHAATSEEHGKFAAYMMLVFGRLDAEKGWTKQLHLGARRNNSTRRFRELGADTGWDSIGDWPQADALGTYLDRLDLENALPKTVIYNLNPADNYVIATMIGNFQDGVTAGKVQFGSGWWFLDQKEAMQWQMNALSNCGMFSKFLGMLTDSRSFMSYPRHEYFRRVLCDLFGRDVENGELPDNDELIGPVIRDICYGNAQRFLGLNV
>NC_008536.1|WP_011687022.1|6681519_6683466_+|hypothetical-protein
MKRLPAVCLLAAACCAQTTIKPIPAAGIEVPPADRAELEAGLARLRAATGNLKKSPLLADVLIYQEAVRYALQYNEFFKPSEIAAAKKLLEQGEQRAAQLAGGESPWTTATGLVVRGYISKIEGSVQPYGLVVPPSYSPNAPHRWRLDAWFHGRDEALSEVNFLSARQRSAGEFTPRDTIVLHLYGRFCNANRFAGEVDFFEALAAVKRQYAIDENRTLVRGFSMGGASTWDFGTHYAGLWAAVAPGAGFSETREFLKLKELPPEWEQKLWHLYDAADYAINLYNVPTVEYHGEIDPQQQAGDVMEKAMAAEGMRLLRITGPQTPHRYHPDSKAELDRILDGIAERGREPYPRRVRFTTWTLAYNRMKWLAIDALGKHWERARMDAEITGDSGVKVDTFNVTAFTLEMGPGGCPLDPARPPVVTVDGVKLTAPVPASDRSWTVHFRKAGAEWTVAPSTAFAGIHKFHGLQGPIDDAFLDSFVFVSPTGTPLAPGVAAWVAAEEKHAIAEWRRQFRGEARVRDDRNITDADIAASNLVLWGDPGSNRVLARIAGQLPVKWTAAGVVAGSQRFDAATHAPILIYPNPLNPKKYVVLNSGFTYREFDYLNNARQTPKLPDYAVVDTTTPPGPRYPGKIVLAGFFDEDWRLQ
>NC_008536.1|WP_011687023.1|6683465_6685409_+|prolyl-oligopeptidase-family-serine-peptidase
MRAAALLLIAASAFAQPAIKRIPGDGIAVPEADRAALAAGLAHLQASIAKLKPGPLLPDVQVFAEAVRFSLEYDEFFKPAEIGAAKKLLEAGEERAAQLAARKSPWTTATGLVVRGYVSKIDRSVQPYGLVVPPSYSADAPHRWRLDTWFHGRNETLTQVNFLGDRMKNQGEFTPRDTIVLHLYGRYCNASKFAGEVDFFEALEAVKRNYAIDENRILDRGFSMGGASVWHFAVHYPSLWAAASPGAGFAESAQYLKIKLTGDTAPPEWEQKLWHYYDAVDYAANLLNLPVIEYHGEIDPQKQAGDMMERAMAAEGLKLARLEGPQTAHKFHPETKVELARQIDAIAERGREARPRKVVFTTFTLHYNQSAWVTIDAMTRHWERARVEAEQSNATEYKATTSNVSGFTLDLQPSARAPFVMVDGQRLETHAPGAVHFRKKGAKWEIAGSSELPGLHKVHGLQGPIDDAFLDSFVFVSPTGSPIAAAAGKWVASEEKRAIAEWRRQFRGDAQVRDDKDVTEADIANSNLVLWGDPSSNRVLARIAGGLPVKWTADGVVLGGRRYAAATHAAILIFPNPLNPKKYVVLNSGFTFREADYLSNARQTPKLPDYAIVDLTVAPDGRFPGKIVEAGFFNEEWALASAPPKDR
>NC_008536.1|WP_083783863.1|6685344_6686601_+|amidase
MWRPGSSTRSGRSLRRHPRIANLLLQFLRWLESGEKTPQDLLALCLSRVAELDGDVRAWVVVGAQPALAEGALAGIPFGVKDIFETSGLPTEFGSPLYRGRRGECDAQIVAHLRLAGAVLLGKTETTPFASFDAAPTRNPRLPGHTPGGSSAGSAAAVAAGMVPFAVGSQTLGSVLRPAAFCGVCGFKPSFGLVSFEGAMPFAPSLDTVGFFTQTAADMKELCSRAFGGRFAADLHRAAAMRVSGRECTERAIEGLRAAGVTIDEIDPPEGWEQLHAAARVINQYEGARTQRARYDEFGEQLGAKLAALIRDGLAIREEEYDAAQAHVEQMRGEISALYWEYPVLLTPAATGPAPEGFAATGDPSPNAPWTAMGVPAITVPLPVAGAPLGLQMTAAWGRDDALVAVAAQLESLLGGIG
>NC_008536.1|WP_011687025.1|6686604_6687471_+|hypothetical-protein
MALRVGLLIMLGAASANGANGFAGAAACRPCHAAIFAAQSSSEHARALARSSAAQPPEWAFGAGVQAITFVRRLDAGYYLEEGRSWYREPDTFDITPGHRSAAGVRYRIFDPSAGILRCFACHSTGPVALDAGESIKPAELGVRCEACHGPAADHVRDPARVKPRNPGKITAGGLNQFCGDCHRKPAAPDETPNLADPWNARHQPLMLAASKCFKASQGKLSCLTCHSPHAPLEQKAAAYDGACTKCHPAARHTQAVGGRACAECHMPAVAAQSHLSFSTHRIAIYPR
>NC_008536.1|WP_157675517.1|6687503_6688430_-|tetratricopeptide-repeat-protein
MLLPVMVAMFLQTDPQALLPLYEQALQRRRKEFGAADPRTAQAARDLGLFLAGIGDPAAARPALAEAVRIDEQAFGAAALQTLADVTELAAVSPPTASEPLWRRATAAQDPGIAIRAWMALGALRSTAGRRAGAAACYRKALARQEEAAGKDSPAIPAVLQALAEVVETRDAIPLLQRALIVGRATQGPHHPSNALIEAALSAKLLAAGRTDDALRAAADALTIDQETLGIDHPRTARVMTALARVLQAQQQIERAESMYRLALSIDENAYGRAHPETRTDVRTLAKFLRDTGRPLEAAELEKGAAAR

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Crispr_ID: NC_008536_13

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_008536_13

6930885-6931005

Orphan

Consensus_repeat	Method
GGCCCGCCTTCTACTGTGCATTTGTCTATTCG	CRISPRCasFinder

1 spacers

The CRISPR arrays of NC_008536_13

>merge|NC_008536|13|6930885-6931005|CRISPRCasFinder
GGCCCGCCTTCTACTGTGCATTTGTCTATTCGCACGCCGCGAAGACTCCCGTCAGAGCCGCGACCGCCAGGGAGCGATCGCTTTTTGCGGGCCCGCCTTCTACTGTGCATTTGTCTGTTCG

>NC_008536|13|13|6930885-6931005|CRISPRCasFinder
GGCCCGCCTTCTACTGTGCATTTGTCTATTCG	CACGCCGCGAAGACTCCCGTCAGAGCCGCGACCGCCAGGGAGCGATCGCTTTTTGCG
GGCCCGCCTTCTACTGTGCATTTGTCTGTTCG

Protein	Signature genes	Signature genes Name	Protein_function
NC_008536.1\|WP_083783874.1\|6916200_6917370_-\|SgcJ/EcaC-family-oxidoreductase	unknown	unknown	gnl\|CDD\|223730
NC_008536.1\|WP_157675541.1\|6935977_6936121_-\|hypothetical-protein	unknown	unknown	unknown
NC_008536.1\|WP_011687213.1\|6932848_6933256_-\|Co2+/Mg2+-efflux-protein-ApaG	unknown	unknown	gnl\|CDD\|180098
NC_008536.1\|WP_011687206.1\|6921785_6923315_+\|glycerol-3-phosphate-dehydrogenase/oxidase	unknown	unknown	gnl\|CDD\|223651
NC_008536.1\|WP_011687209.1\|6928196_6929219_+\|thioredoxin-domain-containing-protein	unknown	unknown	gnl\|CDD\|372611
NC_008536.1\|WP_085952986.1\|6923501_6924275_-\|class-I-SAM-dependent-methyltransferase	unknown	unknown	gnl\|CDD\|379312
NC_008536.1\|WP_157675538.1\|6920535_6921774_+\|efflux-RND-transporter-periplasmic-adaptor-subunit	unknown	unknown	gnl\|CDD\|273776
NC_008536.1\|WP_157675945.1\|6934728_6935934_-\|cation:proton-antiporter	unknown	unknown	gnl\|CDD\|223551
NC_008536.1\|WP_011687204.1\|6917405_6920543_+\|efflux-RND-transporter-permease-subunit	unknown	unknown	gnl\|CDD\|223911
NC_008536.1\|WP_011687212.1\|6931135_6932710_-\|B12-binding-domain-containing-radical-SAM-protein	unknown	unknown	gnl\|CDD\|223963
NC_008536.1\|WP_157675539.1\|6924463_6927661_-\|hypothetical-protein	unknown	unknown	unknown
NC_008536.1\|WP_157675946.1\|6936622_6938278_-\|ammonium-transporter	unknown	unknown	gnl\|CDD\|223083
NC_008536.1\|WP_041858279.1\|6933352_6933574_+\|hypothetical-protein	unknown	unknown	unknown
NC_008536.1\|WP_011687215.1\|6933578_6934670_-\|TIM-barrel-protein	unknown	unknown	gnl\|CDD\|224231
NC_008536.1\|WP_041858278.1\|6929240_6929816_-\|hypothetical-protein	unknown	unknown	unknown
NC_008536.1\|WP_011687217.1\|6936117_6936621_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|274350
NC_008536.1\|WP_011687202.1\|6915661_6916204_-\|GNAT-family-N-acetyltransferase	unknown	unknown	gnl\|CDD\|236088
NC_008536.1\|WP_041858282.1\|6938480_6938660_-\|hypothetical-protein	unknown	unknown	unknown
NC_008536.1\|WP_041858281.1\|6938274_6938457_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|320212
NC_008536.1\|WP_157675540.1\|6930347_6930503_+\|hypothetical-protein	unknown	unknown	unknown

Protein	Function_ID	Function_description	E-value
NC_008536.1\|WP_083783874.1\|6916200_6917370_-\|SgcJ/EcaC-family-oxidoreductase	gnl\|CDD\|223730	COG0657, Aes, Esterase/lipase [Lipid metabolism].	4.89503e-31
NC_008536.1\|WP_011687206.1\|6921785_6923315_+\|glycerol-3-phosphate-dehydrogenase/oxidase	gnl\|CDD\|223651	COG0578, GlpA, Glycerol-3-phosphate dehydrogenase [Energy production and conversion].	9.70184e-174
NC_008536.1\|WP_011687209.1\|6928196_6929219_+\|thioredoxin-domain-containing-protein	gnl\|CDD\|372611	pfam13462, Thioredoxin_4, Thioredoxin.	9.10752e-37
NC_008536.1\|WP_085952986.1\|6923501_6924275_-\|class-I-SAM-dependent-methyltransferase	gnl\|CDD\|379312	pfam13649, Methyltransf_25, Methyltransferase domain. This family appears to be a methyltransferase domain.	2.55449e-26
NC_008536.1\|WP_157675538.1\|6920535_6921774_+\|efflux-RND-transporter-periplasmic-adaptor-subunit	gnl\|CDD\|273776	TIGR01730, COG0845:_Membrane-fusion_protein, RND family efflux transporter, MFP subunit. This model represents the MFP (membrane fusion protein) component of the RND family of transporters. RND refers to Resistance, Nodulation, and cell Division. It is, in part, a subfamily of pfam00529 (Pfam release 7.5) but hits substantial numbers of proteins missed by that model. The related HlyD secretion protein, for which pfam00529 is named, is outside the scope of this model. Attributed functions imply outward transport. These functions include nodulation, acriflavin resistance, heavy metal efflux, and multidrug resistance proteins. Most members of this family are found in Gram-negative bacteria. The proposed function of MFP proteins is to bring the inner and outer membranes together and enable transport to the outside of the outer membrane. Note, however, that a few members of this family are found in Gram-positive bacteria, where there is no outer membrane. [Transport and binding proteins, Unknown substrate].	1.70656e-53
NC_008536.1\|WP_157675945.1\|6934728_6935934_-\|cation:proton-antiporter	gnl\|CDD\|223551	COG0475, KefB, Kef-type K+ transport systems, membrane components [Inorganic ion transport and metabolism].	1.26244e-49
NC_008536.1\|WP_011687204.1\|6917405_6920543_+\|efflux-RND-transporter-permease-subunit	gnl\|CDD\|223911	COG0841, AcrB, Cation/multidrug efflux pump [Defense mechanisms].	0
NC_008536.1\|WP_011687212.1\|6931135_6932710_-\|B12-binding-domain-containing-radical-SAM-protein	gnl\|CDD\|223963	COG1032, COG1032, Fe-S oxidoreductase [Energy production and conversion].	7.99204e-32
NC_008536.1\|WP_011687213.1\|6932848_6933256_-\|Co2+/Mg2+-efflux-protein-ApaG	gnl\|CDD\|180098	PRK05461, apaG, CO2+/MG2+ efflux protein ApaG; Reviewed.	2.33247e-65
NC_008536.1\|WP_157675946.1\|6936622_6938278_-\|ammonium-transporter	gnl\|CDD\|223083	COG0004, AmtB, Ammonia permease [Inorganic ion transport and metabolism].	3.30593e-120
NC_008536.1\|WP_011687215.1\|6933578_6934670_-\|TIM-barrel-protein	gnl\|CDD\|224231	COG1312, UxuA, D-mannonate dehydratase [Carbohydrate transport and metabolism].	3.78728e-67
NC_008536.1\|WP_011687217.1\|6936117_6936621_-\|hypothetical-protein	gnl\|CDD\|274350	TIGR02917, TPR_domain_protein, putative PEP-CTERM system TPR-repeat lipoprotein. This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.	0.00370458
NC_008536.1\|WP_011687202.1\|6915661_6916204_-\|GNAT-family-N-acetyltransferase	gnl\|CDD\|236088	PRK07757, PRK07757, N-acetyltransferase.	8.65548e-11
NC_008536.1\|WP_041858281.1\|6938274_6938457_-\|hypothetical-protein	gnl\|CDD\|320212	cd15084, 7tmA_Pinopsin, non-visual pinopsins, member of the class A family of seven-transmembrane G protein-coupled receptors. Pinopsins are found in the pineal organ of birds, reptiles and amphibians, but are absent from teleosts and mammals. The vertebrate non-visual opsin family includes pinopsins, parapinopsin, VA (vertebrate ancient) opsins, and parietopsins. These non-visual opsins are expressed in various extra-retinal tissues and/or in non-rod, non-cone retinal cells. They are thought to be involved in light-dependent physiological functions such as photo-entrainment of circadian rhythm, photoperiodicity and body color change. Pinopsins belong the class A of the G protein-coupled receptors and possess seven-transmembrane (TM) alpha-helices interconnected by three extracellular and three intracellular loops.	0.00914854

>NC_008536.1|WP_157675540.1|6930347_6930503_+|hypothetical-protein
MKSGIREWEENTAIAAENTAIRKVADLKRVFIAQSGSRSRLLGESKTAKTR
>NC_008536.1|WP_041858278.1|6929240_6929816_-|hypothetical-protein
MKMAVVLMAFSAIAFGQTAAQPPALGYKDSYQLDYMDIRGTINFTNTGLHPNLQSPPNSSDICVNAYVFQPVTDSPDGPLGAAMASCCSCRVAASTVRTITPQLSGPVVVKLVATMPSRSGPACDATVLPTLDLGLAAGYAAGLRAWSVSQPTVLSEQVSTSKFDKVPLGSNEQAKLTQLCAATASKCTCQ
>NC_008536.1|WP_011687209.1|6928196_6929219_+|thioredoxin-domain-containing-protein
MPSSPVVFSVLGAVAALAVTAVRAQEVDKAAMVNGAPILASEIDAKLGNDLAQLQQQIFNLRKKQLNTVIDQKLLEDESARRGVMIAELVQSEVTSHVTPATSAEAEKFFKENSTKLKGDFKSLEEQIRNFLTAQRLQARQQEFLKSLRTAAKVEVFLAPPPVFRSEVSVEGAPSRGGVAAPVTIVEFSDFHCPFCRKAQSVLDNLRAKYGEKIRFVYRDFPLEGLHPQARVAAEASRCAAEQGKFWEFHDRLFHGDPDASQAALSRIAKESGMDLTAFEACRTSGKYKNSVQASAQEGARLGITGTPTFFVNGRMLVGSQSLDEFVSIIDEELAAGAGR
>NC_008536.1|WP_157675539.1|6924463_6927661_-|hypothetical-protein
MNSFVMATALAMATGVCSAADSIGVSCALPYTLHHPDPFFPCVGQHTVQYSTSNTDANAKVTAELLALDGNGNLINSFTVHNGENVELASRLSQTAWRFVPSGGLPQVYAPVPLLHVTVEDRGLKAEAYCSDIPYVQVIQPRGGVVSESDGNNTNVLVAIPLTNPGSLHLFVDGVDILTQVPNSFACLPNVPCNGTVTINGQVVGYSNLIIDVASAIDKPASNTVRVTLTNLACGGHIFRVSSVKLPGVPQLVAGVCNADSLSKAGTSSVFSISITDPTPLKITPIIPTPVAGQVCGGTQITNVSINGKNLSVAGETFTPGNGTTSGDVYKVAINTTLDKTDLVRDAFGAHDAPLGTLDAGSNRLAASAKDVNGNRTYKNLIFATGSVAPVAIDPNAKIFQTAAMETAVSSNLKRLVEAQIDSTFTANAPANTDLQNAFVVGLSASGAQTLFNSLCTAPIKDNPDPTINGLTPGQAFSKKVTAAIKAIPATRVTISSPCSCDPPVNINIKSVNIGTNVACNLTFTDGSFHVRMSLPDVHVVADAVGFCKETFLGACVDGAAVGVEGTADVTGIRLDWDVKATDITGTTTPSPILFAGTTATGAHDITNPFGDQGISTCGLSDVCTFLVQIFTFGAVDLTPTINISQVQDFSAQIGATSKDPVKMTQIKVDPTVINNFNQKASGDISEVHITPSGITAGLVGHFASLAVDPSVPATPGVTLTPAPVPPLPVPNAKDVFIGISDDAINMMFASLTAAGKLQTGAPGGNGCIDTGVTIGTLLPPSCDSLTLDNDVSTVAARGYCHAIKGDACGSVTYNNPALSATDNANLTASEQGECYGAQGLPAGQTCGSLANFNLFFYGACSITPNLNLHAPQPLLFCAKGDVPPRMLFPDNPGTGGAVPAVLRIPSLSVALVIDRDQNHQTTGAFANIPGCFTPGTSTAVDCNVFSACLALNLDFSMAFQTCSDGKPGFVPTFQDVQVLTRQVGTVCGGATSPTTDASVLSSSSNTQITIPLGNNGASFAPPICGAGLDLGGFVSCTQPGVLSIRSENTFLDSRDYLAITCKIQ
>NC_008536.1|WP_085952986.1|6923501_6924275_-|class-I-SAM-dependent-methyltransferase
MHRALVRTMYSGISFVLKNEDSAFLNYGYTPHDSNTTKLELLPEDEADRLSIQLYSRIAGARELRGKDVLEIGCGRGGGASFIARYLQPAALTGVDLSARAVRYCRKRHRSENLKFLRGDAEHLPYPANSFDAVVNVESSHCYPSFERFLTEVARVLRPDGCFLFADMRPREEVARMLEQLKERFVIVEEEVITTNVVHALELDSDRRNLLIQKRAPRFLHKGLQLFGSVSGSPIFEALSAGSWQYVRLVLKKMPVN
>NC_008536.1|WP_011687206.1|6921785_6923315_+|glycerol-3-phosphate-dehydrogenase/oxidase
MYLRLREHNGPWDMIVIGGGATGAGVAVDASTRGYSVLLLEQSDFGKGTSSRSTKLVHGGVRYLEQGNLSLVMEALKERGLLLRNAPHLVRNLGFVVPNYDWWQAPFYGVGLKVYDLLAGKYGFGSSRILSREETLARLPTIRAEDLRGGVIYFDGQFDDARLLIHLLATAFDHGASLFNHTRVVAAACDGVRVRDEETGEEFDAAARVVINATGAFSDSVRRMADPTAAPIIAPSQGIHLVFDRSFLPGDNAIMVPHTSDGRVMFAIPWHGHTVVGTTDTPVPQASLEPVAMEQEIDFILQTAALYLAKPPFRADVLSVFAGIRPLVKQGDAGRTASLSRDHTIIIEDSGIVTIAGGKWTTYRRMAEDCVNQAATLGGLEERPCVTADLPVHGSHRAADAFGALSVYGSDAPAVRELSGDRLHPALPYTSGEVLWAVRHEMALTVEDVLARRTRALFLNARAAVQMAPQVAALMARELGRDQQWIATQLESFRAVAQHYLIGPASLPD
>NC_008536.1|WP_157675538.1|6920535_6921774_+|efflux-RND-transporter-periplasmic-adaptor-subunit
MRNSLMLLRPGNALIRAATVTEQSLLTACRTVGQAILPAAGFQPACPAPTRRVPLHRFASIALPLLLACALFAQQPPELVAVVAKPLDRKLPLPGEISPYQDVEIHAKIAGFVERVLVDRGSAVKKGEPLATLDAPELKTQRAEAQSKVQAMQAQRAEAEARLVGEQGTYDHLKAASATPGVIAGIDLIVAEKRVDAARAQVTAVEAGINAAQSAVKVIEDMQQYLELTAPFDGVITERGVSPGALVGPNSKSLFRLEQNSRLRLVVAVPEPDVSGIAAGAHVTFTVPAYPGQQFTGTIARVAHSVDVKTRSMPVELDVDNAHRQLSPGMYPTVNWPVKRSRPTLIVPGSAVAGNTERTFVIRANNGVAEWVNVSKGVTVTPDTIEVFGPLQPGDMIVKRATDEIREGTKLK
>NC_008536.1|WP_011687204.1|6917405_6920543_+|efflux-RND-transporter-permease-subunit
MWLVRSALRRPVTILVAVVAIALCSILALQRMPADIFPNLGAPAIYVAQPYGGMDPVQMEGYLTYYYEYHFLYITGIEHVESRSIQGAALMKLVFHPGTDMSQAMAQVVGYVNRARSFMPPGAVPPFIVRYDAGSVPVGQLVFSSPIRNPGEMQNIALNQVRPLFAVLPGVSAPPPFGGNQRTIVVRLNPERLSAYRISPEEAIQAVNRATLVMPSGNVRIDDLTRIASSNATLGGNLAELGSAPIRTGAGPTVYLRDIGVVENGTDILTGYAHVNGRRTVYIPVTKRADASTLDVIRRVRAAIPTFKNAVPEDVDIKLEFDQSGFVVNALKGLVTEGALGAILTGLMVLLFLRDWRSALIVMLTIPFALLSAVVWLWAAGQTINIMTLGGLALAVGVLVDEATVEIENIHSHMTGGLTRARAVVDACSKTAVARLLSMFCVLSVFVPSYFMVGVGRQLFVPLALAVGFAMISSYLLSSSLVPVLSAWFMKQAPETERHPAAEDPRTGFLPRVLRFRWLVAGAYFAIAGLALFLMLPHLSLEIFPTVDSGEFQLRLRAPTGTRIERTELIALRALDVIKQEVGANNVRITTDFVGVQPASYPVNTIYLFTSGPHEAVLKVALQPTATLRGPALEERLRKRLPEVLPGVAFSFEAGDIVSQVMSFGSPTPIEVAVQGANLAANRAFAEKLRTELSKVPELRDLQYGQPLDYPTVQVAIDRDRAGQFGLNMGNVARSLIAATSSSRFIEPNYWRDPVSGNGFQIQVEIPQNKMASIQDVRNIPVMEDGEARPLLGDVASVGYGTTMGEVDRYNMQRMVSLTANIHGKVLGDAAADVRAAIARAGAPPRGVTVNVRGQLPPLEETVGGLRTGLLLSILVIFLLLAANFQSLRLALAVLFTVPAVLCGVAAMLLITGTTLNVESFMGAIMAIGVAVANAILFVTFAEMRRHEGVDAIDSAVFGARTRRRAILMTASAMIAGMIPMALGIAEGGSQAAPLGRAVIGGLAAATLSTLFVLPSLYTILQRRAGTQSPSLDPDDSASRYYDHA
>NC_008536.1|WP_083783874.1|6916200_6917370_-|SgcJ/EcaC-family-oxidoreductase
MRYVACIFLMSAGCLAQVVETDIAYDRFPDTRLDILYPKEAASGLRPGVIMFHGGGWIRSTKETMMTAFCKPFLEQGFVVANVEYRVAMAATAPAAVDDALKAAQWFYDRAAQYHVDTRRIVVTGASAGGHLALMVGMTSKIPIAAIVNGYGVTDVADLLGGPHRQGFAAQWLPEQPGRLELAKRMSPMTYVRKGLPPVLTVQGENDHTVPYEQGVRLTAALKEAGDDAEMMTVPGAGHGFSTEQWPAVHARMFAFLRARGILAAAAVTADEAAIREIVARYVDARDQKDPQATAALFTEDADQLVSSGEWRRGREALVKGAMASSEASGGKRTITVETVRFLSADVAIADGRYEIAGPTPRRMWASLIMKRTAEGWRIAAIRNMLPAK
>NC_008536.1|WP_011687202.1|6915661_6916204_-|GNAT-family-N-acetyltransferase
MREFTLRKAVPEDVGSLRALIDRSVRGLQAGDYTASQIEESLRSVYGVDTQLIADGTYFVVEQDGAIVGCGGWSKRKTLYGGDQFDGREDSLLDPVCDAAKIRAFFVDPAWARRGIGAMLLEACEGTAVAAGFRRLEMGATLTGVAFYRAKGYRSAEEIGVAMPNGESLRIVRMWKAVGV
>NC_008536.1|WP_011687212.1|6931135_6932710_-|B12-binding-domain-containing-radical-SAM-protein
MKILLYNPDNGVTQNFMPHLWMFLLQSLTPSQHEVLLIDGNTQPMTDPELVQYALDQKIGLVGIGAMTRMIAKAYRVADALRAAGIKVVMGGPHVTECPDEALGRDGGGRHADAIALGEADETWPRIVADAAKGELREVYKPVDAFGQEQKPSLKDYPQIPWQKLDIDQFNRIPGFFKRIMRHYGHAWETFHIIPIESGRGCPYGCEFCTVTGFFGDSIRFRTNESIVTEMLALKERAKASSGKIAVFFVDDNFAINVKRTKSLLRDIIAAGAQLSWVGQISANLLRDEELLDLIAESGGKWIFIGMESLDVANLASVNKSFNKPSEYAGVLQKLAQRNVYAITSFIFGLDNDTPGVASRTLEQIRDWPPVLPVFGQITPFPATPLYDRLAKEGRLTRPKHWLEFAPFRMAHTPLKLSIPEVQDEVQYAWTNSYSPEATKLALDSIADEPVPYKISHFVARIFFRGIYFPPKGMWQWLKLIGQNRASVFRIVRESFTQWHGTDGVARHSDFNRGPRYAPVANEE
>NC_008536.1|WP_011687213.1|6932848_6933256_-|Co2+/Mg2+-efflux-protein-ApaG
MPDLRSEPTPTSEAVTNNIRVEVIARYAPENAQQGEFVFQYTVRITNEGTESVQLRSRYWIITDALDHVEEVRGPGVVGEQPALAPGQSFKYSSWCPLKTPTGTMRGTFQMVGANGAEFDVEIAPFALRARVTIH
>NC_008536.1|WP_041858279.1|6933352_6933574_+|hypothetical-protein
MAKKKNTEEAPEGILETAAKTLGTAAGKIAAAVGVTADKKATPPSKIKIPKLASKNKSRLPRKQKKALKKAEN
>NC_008536.1|WP_011687215.1|6933578_6934670_-|TIM-barrel-protein
MNRRAFVSTSGAAALALGSSISPKTASAAPKAMMKLGCQSAPTNETHLKYFARYGVRNICGYPTIAGDRLYASAEELKKMRDLADANGISIDCLAPPFLASSHIDREKNPAIMLAQSPERDRDIEAMQTMIRNCAAAGIPSIKYNMSILGVLRTGRSPGRGDATYSTWSLKNAHPETPLTKAGRVTADQAWERITYFLEKVIPVAAEYKVRMACHPHDPGVPPEGYQGVTRVLGTVDGLKRFVSIKENPYHGLNFCQGTVSEMLQDPGKEIYDVIRYFGSRQKIFNVHFRNIRGHRDEFVETYPDEGDVDFVKAIQTYKEVGYPYLLMPDHVPVAPNDPGGLQSFAFCYGYIRALIQAVDRIG
>NC_008536.1|WP_157675945.1|6934728_6935934_-|cation:proton-antiporter
MLDTSGSAHIPLSMLIIFVSAKLMAELFERVNQPGIVGEILAGVLIGPSVLGLIGPSEFLTALADLGAMFLLFRVGLDVRSSELLQVGGTATVVACSGVVVPFLFGWGILTAWGASANEAIFVGASMVATSVGITAQVLSAKGLLHAISSKIILAAAVIDDVLGLLVLAVVSSLTHGQLNIPALALTAVMAVGFTLVIAKWGTHAMGRVVPHVDQKLRVGEAQFALAMSVLFALSVAAVYIGVAAIVGAFLAGLALAESTGQRVRDLAHGVTELLVPFFLAGIGLHVSLAAFSSPRNALLAVVILLAAVVSKFIGCGLGALGLGKADALRVGVGMIPRGEVGMVVAQIGLGFGIITQNVYGVVVFMSVATTIVAPPLIKIAFRGLLKTGQAEAPEEVFRIG
>NC_008536.1|WP_157675541.1|6935977_6936121_-|hypothetical-protein
MTKKWSFFCAAALMSAYALITHGAPPLAVAAGIGFGALLTVRSTRSA
>NC_008536.1|WP_011687217.1|6936117_6936621_-|hypothetical-protein
MTGELAVTQNTALRLPPVPWRDPHTVSPAQLAEYIAGLERACAENPRCADLRTCLGMAHAMNYDVYRSMDALEYAVEVDPQHFFAQLKYSELFYRLRALVRAEQETIKAMDLAGNAWELSLARKQLQEIRRLSREGTQKPEWTKSLKSPAVVLVAMAIILCLVVNWK
>NC_008536.1|WP_157675946.1|6936622_6938278_-|ammonium-transporter
MTSVKRTLLLFIPLILSASLALAQAPAAASPPAPAAPPVAITDADVKNVDAPKPDVRLKGDPDGALTGTVSDVAVSDAKKGLTIGDLVNQVGQNKVAINFTWTLITGFLVMFMQAGFAIVETGLCRAKNANHTMMMNFMVYGIGMLAYWLIGFSIQMGGVGGVGNLGGAPPLNTEHVITLFGKGFGLYGQHGMFLTQGGTYDVAVMVIFLFQMVFMDTALTIVTGSAAERWKFAAFLVSSFMLGAFIYPLFGNWAWGGGWLATLGTNFGLGKGYCDFAGSGVVHAVGGLTALALSIIVGPRLGKYNRNGKPNAIVGHDIVLVLTGCFILAFGWFGFNPGSTLGASGSGSLRIGSIAVNTMLAGMAGGFGAMFYMWMRYGKPDASMSGNGLLAGLVAITAPSGFVNTVGAVIIGLIAGVLVCLSVEFIDRVMRVDDPVGAISVHGVNGIWGVIAVGLFADGKSNYGGSWNGVNGSVTGLFYGDPSQLVAQLIGVSTLVGGVFVLSFVVNLAIDAVVGQRVSAKAELEGLDLPEMGQVGYPEFELKARTVGVQ
>NC_008536.1|WP_041858281.1|6938274_6938457_-|hypothetical-protein
MALLGILVTFLGFVISFLSLSMTSSVNGRLVMVLIGLAVSLTGIIGIINRAYLKNANWRR
>NC_008536.1|WP_041858282.1|6938480_6938660_-|hypothetical-protein
MGANPTQAQALVLFLFGFTALSAGLAADVSYLMVGLGLLLLGGSVMLFLKCKPWEHNEE

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Crispr_ID: NC_008536_14

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_008536_14

9083705-9083794

TypeI-A

Consensus_repeat	Method
CAGCCACGATTGGCTGCCCCACAA	CRISPRCasFinder

1 spacers

csa3,cas6

The CRISPR arrays of NC_008536_14

>merge|NC_008536|14|9083705-9083794|CRISPRCasFinder
CAGCCACGATTGGCTGCCCCACAAAGGGGTTTTCATCCCTTTAAATGGCGCGCAGCGCCATCGCGACAGCCAGGATTGGCTGCCCCACAA

>NC_008536|14|14|9083705-9083794|CRISPRCasFinder
CAGCCACGATTGGCTGCCCCACAA	AGGGGTTTTCATCCCTTTAAATGGCGCGCAGCGCCATCGCGA
CAGCCAGGATTGGCTGCCCCACAA

Protein	Signature genes	Signature genes Name	Protein_function
NC_008536.1\|WP_011688862.1\|9084236_9085382_-\|IS110-family-transposase	unknown	unknown	gnl\|CDD\|226077
NC_008536.1\|WP_011688865.1\|9087725_9088160_+\|hypothetical-protein	unknown	unknown	unknown
NC_008536.1\|WP_157675707.1\|9091575_9092484_-\|hypothetical-protein	unknown	unknown	unknown
NC_008536.1\|WP_157675999.1\|9079762_9080011_+\|hypothetical-protein	unknown	unknown	unknown
NC_008536.1\|WP_011688861.1\|9083148_9083529_+\|hypothetical-protein	unknown	unknown	unknown
NC_008536.1\|WP_011688855.1\|9076492_9077323_+\|DUF1080-domain-containing-protein	unknown	unknown	gnl\|CDD\|368908
NC_008536.1\|WP_011688856.1\|9077371_9077713_+\|winged-helix-turn-helix-transcriptional-regulator	csa3	COG0640_csa3_CAS-I-A	gnl\|CDD\|238042
NC_008536.1\|WP_011688869.1\|9090055_9091573_+\|AAA-domain-containing-protein	unknown	unknown	gnl\|CDD\|223616
NC_008536.1\|WP_011688853.1\|9075484_9075880_+\|hypothetical-protein	unknown	unknown	unknown
NC_008536.1\|WP_157676000.1\|9080953_9083149_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|369609
NC_008536.1\|WP_157675705.1\|9085482_9086565_-\|TIGR03790-family-protein	unknown	unknown	gnl\|CDD\|274784
NC_008536.1\|WP_041858629.1\|9074453_9075410_-\|rubrerythrin	unknown	unknown	gnl\|CDD\|153104
NC_008536.1\|WP_157675706.1\|9088308_9089058_-\|CRISPR-system-precrRNA-processing-endoribonuclease-RAMP-protein-Cas6	cas6	mkCas0066_cas6_CAS-I:CAS-III	gnl\|CDD\|337605
NC_008536.1\|WP_011688867.1\|9089373_9089577_+\|cold-shock-protein	unknown	unknown	gnl\|CDD\|224197
NC_008536.1\|WP_049873472.1\|9077745_9079404_+\|STAS-domain-containing-protein	unknown	unknown	gnl\|CDD\|183265
NC_008536.1\|WP_011688868.1\|9089649_9089868_+\|translation-initiation-factor-IF-1	unknown	unknown	gnl\|CDD\|178954
NC_008536.1\|WP_011688859.1\|9080252_9080681_+\|hypothetical-protein	unknown	unknown	unknown
NC_008536.1\|WP_011688854.1\|9075848_9076421_-\|histidine-phosphatase-family-protein	unknown	unknown	gnl\|CDD\|366010
NC_008536.1\|WP_011688864.1\|9086793_9087726_+\|LysR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|223656
NC_008536.1\|WP_011688871.1\|9092655_9093624_+\|beta-propeller-fold-lactonase-family-protein	unknown	unknown	gnl\|CDD\|274824

Protein	Function_ID	Function_description	E-value
NC_008536.1\|WP_011688862.1\|9084236_9085382_-\|IS110-family-transposase	gnl\|CDD\|226077	COG3547, COG3547, Transposase and inactivated derivatives [DNA replication, recombination, and repair].	1.73439e-22
NC_008536.1\|WP_011688864.1\|9086793_9087726_+\|LysR-family-transcriptional-regulator	gnl\|CDD\|223656	COG0583, LysR, Transcriptional regulator [Transcription].	1.33787e-51
NC_008536.1\|WP_011688855.1\|9076492_9077323_+\|DUF1080-domain-containing-protein	gnl\|CDD\|368908	pfam06439, DUF1080, Domain of Unknown Function (DUF1080). This family has structural similarity to an endo-1,3-1,4-beta glucanase belonging to glycoside hydrolase family 16. However, the structure surrounding the active site differs from that of the endo-1,3-1,4-beta glucanase.	4.04357e-47
NC_008536.1\|WP_011688856.1\|9077371_9077713_+\|winged-helix-turn-helix-transcriptional-regulator	gnl\|CDD\|238042	cd00090, HTH_ARSR, Arsenical Resistance Operon Repressor and similar prokaryotic, metal regulated homodimeric repressors. ARSR subfamily of helix-turn-helix bacterial transcription regulatory proteins (winged helix topology). Includes several proteins that appear to dissociate from DNA in the presence of metal ions.	2.59275e-14
NC_008536.1\|WP_011688869.1\|9090055_9091573_+\|AAA-domain-containing-protein	gnl\|CDD\|223616	COG0542, clpA, ATP-binding subunits of Clp protease and DnaK/DnaJ chaperones [Posttranslational modification, protein turnover, chaperones].	6.14264e-73
NC_008536.1\|WP_157676000.1\|9080953_9083149_+\|hypothetical-protein	gnl\|CDD\|369609	pfam07944, Glyco_hydro_127, Beta-L-arabinofuranosidase, GH127. One member of this family, from Bidobacterium longicum, UniProtKB:E8MGH8, has been characterized as an unusual beta-L-arabinofuranosidase enzyme, EC:3.2.1.185. It rleases l-arabinose from the l-arabinofuranose (Araf)-beta1,2-Araf disaccharide and also transglycosylates 1-alkanols with retention of the anomeric configuration. Terminal beta-l-arabinofuranosyl residues have been found in arabinogalactan proteins from a mumber of different plantt species. beta-l-Arabinofuranosyl linkages with 1-4 arabinofuranosides are also found in the sugar chains of extensin and solanaceous lectins, hydroxyproline (Hyp)2-rich glycoproteins that are widely observed in plant cell wall fractions. The critical residue for catalytic activity is Glu-338, in a ET/SCAS sequence context.	5.82087e-111
NC_008536.1\|WP_157675705.1\|9085482_9086565_-\|TIGR03790-family-protein	gnl\|CDD\|274784	TIGR03790, conserved_hypothetical_protein, TIGR03790 family protein. Despite a broad and sporadic distribution (Cyanobacteria, Verrucomicrobia, Acidobacteria, beta and delta Proteobacteria, and Planctomycetes), this uncharacterized protein family occurs only among the roughly 8 percent of prokarotyic species that carry homologs of the integral membrane protein exosortase (see TIGR02602), a proposed protein-sorting system transpeptidase.	3.57981e-119
NC_008536.1\|WP_041858629.1\|9074453_9075410_-\|rubrerythrin	gnl\|CDD\|153104	cd01045, Ferritin_like_AB, Uncharacterized family of ferritin-like proteins found in archaea and bacteria. Ferritin-like domain found in archaea and bacteria (Ferritin_like_AB). This uncharacterized domain is a member of a broad superfamily of ferritin-like diiron-carboxylate proteins whose function is unknown. This family includes unknown or hypothetical proteins which were sequenced from mostly anaerobic or microaerophilic metal-metabolizing and/or nitrogen-fixing microbes. The family includes sequences from ferric-, sulfate-, and arsenic-reducing bacteria, Geobacter, Magnetospirillum, Desulfovibrio, and Desulfitobacterium. Also included are several nitrogen-fixing endosymbiotic bacteria, Rhizobium, Mesorhizobium, and Bradyrhizobium; also phototrophic purple nonsulfur bacteria, Rhodobacter and Rhodopseudomonas, as well as, obligate thermophiles, Thermotoga, Thermoanaerobacter, and Pyrococcus. The conserved residues of a diiron center are present in this uncharacterized domain.	2.54706e-35
NC_008536.1\|WP_157675706.1\|9088308_9089058_-\|CRISPR-system-precrRNA-processing-endoribonuclease-RAMP-protein-Cas6	gnl\|CDD\|337605	pfam10040, CRISPR_Cas6, CRISPR-associated endoribonuclease Cas6. Cas6 is a member of the RAMP (repeat-associated mysterious protein) superfamily. It is among the most widely distributed Cas proteins and is found in both bacteria and archaea. Cas6 functions in the generation of CRISPR-derived guide RNAs for invader defense in prokaryotes.	1.85571e-06
NC_008536.1\|WP_011688867.1\|9089373_9089577_+\|cold-shock-protein	gnl\|CDD\|224197	COG1278, CspC, Cold shock proteins [Transcription].	8.26534e-32
NC_008536.1\|WP_049873472.1\|9077745_9079404_+\|STAS-domain-containing-protein	gnl\|CDD\|183265	PRK11660, PRK11660, putative transporter; Provisional.	8.25967e-167
NC_008536.1\|WP_011688868.1\|9089649_9089868_+\|translation-initiation-factor-IF-1	gnl\|CDD\|178954	PRK00276, infA, translation initiation factor IF-1; Validated.	6.3762e-38
NC_008536.1\|WP_011688854.1\|9075848_9076421_-\|histidine-phosphatase-family-protein	gnl\|CDD\|366010	pfam00300, His_Phos_1, Histidine phosphatase superfamily (branch 1). The histidine phosphatase superfamily is so named because catalysis centers on a conserved His residue that is transiently phosphorylated during the catalytic cycle. Other conserved residues contribute to a 'phosphate pocket' and interact with the phospho group of substrate before, during and after its transfer to the His residue. Structure and sequence analyses show that different families contribute different additional residues to the 'phosphate pocket' and, more surprisingly, differ in the position, in sequence and in three dimensions, of a catalytically essential acidic residue. The superfamily may be divided into two main branches. The larger branch 1 contains a wide variety of catalytic functions, the best known being fructose 2,6-bisphosphatase (found in a bifunctional protein with 2-phosphofructokinase) and cofactor-dependent phosphoglycerate mutase. The latter is an unusual example of a mutase activity in the superfamily: the vast majority of members appear to be phosphatases. The bacterial regulatory protein phosphatase SixA is also in branch 1 and has a minimal, and possible ancestral-like structure, lacking the large domain insertions that contribute to binding of small molecules in branch 1 members.	1.12608e-54
NC_008536.1\|WP_011688871.1\|9092655_9093624_+\|beta-propeller-fold-lactonase-family-protein	gnl\|CDD\|274824	TIGR03866, PQQ_ABC_repeats, PQQ-dependent catabolism-associated beta-propeller protein. Members of this protein family consist of seven repeats each of the YVTN family beta-propeller repeat (see TIGR02276). Members occur invariably as part of a transport operon that is associated with PQQ-dependent catabolism of alcohols such as phenylethanol.	1.23058e-25

>NC_008536.1|WP_011688861.1|9083148_9083529_+|hypothetical-protein
MPEPHELMAQLAEGLTRTQSELVVKDIRDAEKAREAGRRHEIGNLTRQLFRIVDEHSRLGHPLFMSIGTAQIYIVDRRADALAECARCHVALPVHVEERAFVPYFLKCPDCGGDVLPREGIKRSAG
>NC_008536.1|WP_157676000.1|9080953_9083149_+|hypothetical-protein
METGPPTAARWSKESGPGTVTFADPKALITTATFTAPGAYVIKLTVDNGQTTSASTLNVKVETPPPVRQLDAVYTKNFQIHSTLWNARAKSLMVNWIPHCIDQINRNDLTQGPGGIDNFVEAGKALRGEPHGLHKGYVFSNAWVHQTVEAMSIALMIDPQGDAEIVGAHKKMRATLDDWIPKILAAQEPDGYLQTAFTLPREGARGNVIDTSNFKHWDPAHRGDHEGYTAGYFIESAINHYLMTGKKDARLYNAAKKLADCWNNNLGPAPKKPWYDGHQQMEQALVRFGRFVNDMEGGGKGQKYIELAKFLLDSRYTAAATERDRQEYDQSHLPVTQQYEAVGHAVRAVYTYSGMADVAVETHDPDYQSAVKSLWDNIVNKKYYVTGGVGSGETSEGFGPNYSLRNNAYCESCSSCGEIFFQWKMNLAYHDAKYVDLYEQTMYNALLGGTDLDGKVFYYTNPLDANAPRTSWHVCPCCVGNIPRTLLMMPTWVYAKSPDGVYVNLFVGSTITVENVGGTDVEMVQATDYPWKGKVAITVNPKASKTFSVRVRVPDRGVSSLYRATPDANGITSLAVNGKPVKIAIDKGYAVITRDWKAGDKIDLVLPMRAQRVHGSEKLEATRGKVALRYGPLMYSIEKVDQDITKPLAPNSELSTEWRGDLLGGVIVIKGKFADGSPMLAIPNFARTNRDPELPPPAPVAAPTGAPAPGEEPGVRRGPRPATSIVWITEA
>NC_008536.1|WP_011688859.1|9080252_9080681_+|hypothetical-protein
MKDRFEVARRIMTFVLVVQAILGFVLDWSPNHLLNPEWHGHARFHGALLLFLLTGVSGTGLWLLWRKSKEPEVAIKVAGLISFSMWTPFFYVTFLLPGSTLWAGPPANVPHIAGWVFYPNVVVAALFLAITAVAWRLPKRQS
>NC_008536.1|WP_157675999.1|9079762_9080011_+|hypothetical-protein
MNAQSQTAPAGQQDQQKTQVFVGKVVKIPDGRFALVTDEQAGKGVYLDDQEKAKGFEGKNVKVTGTLEVAKNLVHVSDIQLA
>NC_008536.1|WP_049873472.1|9077745_9079404_+|STAS-domain-containing-protein
MPKLVLCLRQYTWQIFVKDLIAGLTVGLVALPLAMAFGIASGVTPQAGIYTAVVAGFIISALGGSRVQIGGPTGAFVVIVSGIVLKFGISGLLMVTAMAGVLLLVMGATGLGTAVRFIPRPVTIGFTNGIAVLIASTQIRDFLGLKIAAVPSEFLLRMEKLGAHLNTIDPVTAVVGGVSLGIILLWPLVTKRVPGSIVALLAGTALAIVLKLPVETIGSKFGGIPTGLPTFHIPQFRADLILPLLPSAMTVALLAAVESLLSAVVADGMSGDKHNSNVELIAQGIANVISPMVGGLPATGAIARTATNIRSGAKTPVSGMIHALTLLMILLVAAPLAKFIPLATLAAVLFVVAYNMGEWREIVGILRLGRAERVVWVATFGLTVVADLTVAVEVGMTLAALLYIYRVSQTTTIAPVTDAYIEKGRPHVLQGKDIPQFVTILRIHGPFLFGTTEKLADATEDLSHYGHVVILRVRNMTAIDATGLYALEKLAERLHTTGRHVLVCGARRQPRTMLERADFVSVIGQENILPHVDAALARARILHHFAENQRSA
>NC_008536.1|WP_011688856.1|9077371_9077713_+|winged-helix-turn-helix-transcriptional-regulator
MPDALRRFKAEIFQALAHPTRIAIVEALRHGELPAGKLIERLGLEQANASQHLAVLRSKQIVVNRKDGNQVFYSLRSPLLIDVLDIMRRYFQAQLAETMAALGEMEREQEVTR
>NC_008536.1|WP_011688855.1|9076492_9077323_+|DUF1080-domain-containing-protein
MTYRRAFYLVCAISLCLAAGLVAQQQKNPGYTDTAILPGQNWHVHDSNRPHPNMVTPGKVLGAPPSDAIVLFDGKDLSRWMQHGRGADRGKDVDPKWKVTDGYFEVAPGTGSLLTRDKFGDVQLHIEWSEPTDIKGQDQDRGNSGVLLMDRYEIQVLDSWGNVTYADGQAGSLYGQWPPLVNPIRPPGEWQSYDIVFESPRFDGEKLVRPAYATLFFNGVLVHHRKEILGTMVHRAVAKYSPHANEEPLSLQDHGHKVRYRNVWIRRLQGYDQPER
>NC_008536.1|WP_011688854.1|9075848_9076421_-|histidine-phosphatase-family-protein
MRELWLIRHGETEWSLSGAHTGRTDIPLTANGRENAATIGRYLGGRQFALVLVSPRQRALDTCRLAGYERDAVIDPNLCEWDYGDYEGLTTPQILARNPAWSLWTDGAPRGESPGQVAARADTVIARALTADGDMALFAHGHILRVMAARWLGLPPADGRLFAFGTGRLSTLGFERETRVITRWNLSPSA
>NC_008536.1|WP_011688853.1|9075484_9075880_+|hypothetical-protein
MALVDLTKQLAKEALLSATQDPKPATPAPPSPENVGAIVMGQVHSMQKALKEDEELVVWFANAIETLRVMEIFLPSPKLAVLSGHDTDHNLTRVIAPVETLQLVAKVKKVAAGSKPVRVGLVMPKAKDSNG
>NC_008536.1|WP_041858629.1|9074453_9075410_-|rubrerythrin
MRSFDSLTEREILALAISLEEEDERIYGDVADGLREDYPGSAEVFEGMRVEESGHRRRLIELFQKRFGNHIPHLRRQDVRGFVDRRPVWLMRPLPLEKVRSMAASMEMETRRFYEKASARAKDADVRQLLDDLAQEERAHRDRAVELSEDKLDSRTRRSEEENSRRLFVLQVVQPGLAGLMDGSVSTLAPVFAAAVATHNSGDAFRVGLAASLGAGISMGFAEALSDDGSLTGRGHPWARGLICGAMTTVGGIGHTLPFLIPDYRAAMTAAIAVVIVELGVISWIRNHYMDTPAWSAALQVGLGGVLVFITGILIGSS
>NC_008536.1|WP_011688862.1|9084236_9085382_-|IS110-family-transposase
MKKDSIARLQVTKSQIRRMAAKQRLTVGLDLGDRSSRYCILDEAGEKASEDQLPTSKAGLDMLFAKMAPCRIALEVGTHSPWVSRHLAAMGHEVIVANPRKVRLITQSVKKNDRMDAEQLARLARVDPRLLAPIRHRGPEAQADLAVIRGRAELVEGRTKLINAARGLTKPMGERLKSCDADTVKESMADGLSEATQKVIRPLLKSVEVITQQIKGYDQQIQEIEKRYPETKLVKQVHGVGPLVSLAFILTLEDAERFEHSREVGPYLGLTRKQRESGESAPELGISKAGDELVRRLLVQAAHCILRQDAPDSDLKAWGLTKVGAGAGKKGSKSRKKKAVVAVARKLAVLLHHLWVTGEVYDPQYNRKAVEASKRSKKAAA
>NC_008536.1|WP_157675705.1|9085482_9086565_-|TIGR03790-family-protein
MRLLLLFAAGVILHAQTGDNVLLVVNRNSPISRQIGDYYRPRRSVPVKNVCTIQTTSEEEINWKIYEEQIEQPVGNCLKKAGLVERVYYIVTTMGVPLKVDGPGAGPTAEHASVDSELALLYGKLKGARHSRAGGVPNPFFQRRDTAFQHPMFPIYLVTRLAAYDLADVKAMIDRSLNARNRGKFVIDLQSAKDEPGNDWLRTAAMLLPGKRVVLDETTTPLYNQTNVIGYASWGSNDDHRKQRWLHFQWLPGGIAAEFVSTSARTFKRPPDEWNYTSWEDKQHWFGGSPQGLVADLIHGGATGASGNTYEPYLSGCVRPDFLLPAYNQGRNLAESYYLAMVQLSWQGVIVGDPLCVLKP
>NC_008536.1|WP_011688864.1|9086793_9087726_+|LysR-family-transcriptional-regulator
MDFDQLHTFLEIVRLKSFSKAAQTCYRTQPAISAQVRQLEQELRADLFERFGSRISLTTAGKIFSEYAEQMLDLRRRVQDAIAELETNPRGELVIAANEATCIYVLPKVFSEYRSQFPAVQLQVLRSYGSRVVEAVMENSADFGLTQLPVEEKRLQVVNVYRDEIRLIAPARHPLASRPVVTAQEVAEHFLVLPKYGKTRTRLNEWLEAVEDEVRISMELDSTEMMKHFVIAGLGVSFMAASNCREEIAAGKLRAVPLGPEPMMRRLGLIYRKDKALSKAALGFIQVVLDNVGEETGTLKDKPKAPRVVA
>NC_008536.1|WP_011688865.1|9087725_9088160_+|hypothetical-protein
MTCRRCRKKFDEFETRCPHCGETNDHVAGMFQTSSVLISTSGTERVYRSVEEVPAALRTRLLKSTNGANSATILIADRRGRQEIAKAMRNLPGPTQRRWMQAILGAEGASTAMNWLTPARRRAILVVVTLFTLATIALLFTKFR
>NC_008536.1|WP_157675706.1|9088308_9089058_-|CRISPR-system-precrRNA-processing-endoribonuclease-RAMP-protein-Cas6
MPPSVYSRLFEPGAALGAAPSGLADWPRPFVLRVAHLDGLTVPAGDSFYLDAHVFDLHQPALVHFRAALSRLAEKGLGPGRGRAELERTEQLDLEGGAQAVWEAPAAASVAILDRDPEPVETVAVRFLTPTELKSDGALAGRPEFPILFGRLRDRISTLRSLYGAGPLEIDFKAMGERAARIELRRSEVAWEQVKRKSGRTGQVHPIGGFTGEAEYAGDLAEFVPWLRAARWVGVGRQTVWGKGDVRVK
>NC_008536.1|WP_011688867.1|9089373_9089577_+|cold-shock-protein
MKEKGTVKWFNAAKGYGFIQRENGEDVFVHFSAIQTEGYRTLDEGSSVEFEVTKGPKGLQATNVTAA
>NC_008536.1|WP_011688868.1|9089649_9089868_+|translation-initiation-factor-IF-1
MSKEDSIEVTGTVLEKFPSGLFSVQLEHERVVLAHLAGRLRRNRIRVLAGDKVTLELSPYDLTKGRITFRHR
>NC_008536.1|WP_011688869.1|9090055_9091573_+|AAA-domain-containing-protein
MKDPDRPGERRRPRVKNADAAVLKSENGAEKAKTAQNRVKRQQSDPVEDLTAVLSQKVVGQPAATRVIVPYIQMFQAGLAPEGRPVGVFLLLGPTGTGKTKTIEALADILHGSEKNVLKVDCGEFQMEHEVAKLIGAPPGYLGHRETQPMLTQQKLNAVTSEKCALSLVLFDEIEKAAPSMTRLLLGVLDKGLLRLGDNSVVNFEKSLVFLTSNLGAREMMRELNPEFGFQSAISPERADLTSKLQNIALVAVRKRFSPEFVNRIDCIITYQPLTIESLSTILDQHIIDLQNHVNTRLGNRSFALDVPFETRQFLLQKGTSAEYGARELNRTIHRYLTQPLATMVATNQIAPGVGVVAAIGPGDKLELRTTGGPGPVAAHPTVLLVDDNRDLLHFLERLMADAGWTLLTAESATEAKRLMQEHKPNAALLDYMLPDGNGVELGVEFLQNVPQMLVIVMTGTILPPEEEALCEEHNFPVLRKPFLASDVMNQIRSRLMPVTGVVRA
>NC_008536.1|WP_157675707.1|9091575_9092484_-|hypothetical-protein
MTNLLRTTFRLTGVGLAAGLLMAAPVARPGMLNYVEGQVTIDGHSMGSKSVGQTEVEPGQILTTQQGRAEMLLTPGVFLRLSDHSAARMVSPSLTDTRVELLQGEALVEAQDVRKENRIDVIDHGVGTLLEKKGIYRFDADHPMVAVFDGKAKVLTNDEKGVELGKGKELALNTGGELKGQKFDRDQVDSLYQWSKLRSEYDAQANAASARTIMLENPGWYYGTGWYWNPWYSSWAFVPGAGFGYSPFGFGFYSPGYLAYGRPFYGYRGAFRGGFRGAPMVVRPGRAIGGGGAVHLGRGARM
>NC_008536.1|WP_011688871.1|9092655_9093624_+|beta-propeller-fold-lactonase-family-protein
MRLVHCAATLLTLAGLLPAADTPAVALIVGNKEENSLTIVDPDSGKVVARMPTGEGPHEVAVSADGKLAFVANYGTAQAPGSTISVIDLVGQKELRKVSLGPLRRPHGLAVSGGKVYFTAEANRLVGRYDPASNQIDWLMGTGQGTTHMVIAGPAPDQLFTANIGGDSISVIERNTVTAIPVGKGPEAIDLSPDGKELWTAHSRDGGVSIIDVPSKKVVQTLSLGTKRSNRLKFTPDGKRVLITDLDAGELLVLDAASRKEIQRVKLGKTPEGILISRDGARAYVCVAGDDQIAVIDLKTLQVTGHLTTGKGPDGMAWAVRQ

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity
NC_008536_10	10.1\|6146974\|40\|NC_008536\|CRISPRCasFinder	6146974-6147013	40	NC_008536.1	40823-40862	1	0.975
NC_008536_10	10.1\|6146974\|40\|NC_008536\|CRISPRCasFinder	6146974-6147013	40	NC_008536.1	2383305-2383344	1	0.975
NC_008536_10	10.1\|6146974\|40\|NC_008536\|CRISPRCasFinder	6146974-6147013	40	NC_008536.1	2578879-2578918	1	0.975
NC_008536_10	10.1\|6146974\|40\|NC_008536\|CRISPRCasFinder	6146974-6147013	40	NC_008536.1	2854250-2854289	1	0.975
NC_008536_10	10.1\|6146974\|40\|NC_008536\|CRISPRCasFinder	6146974-6147013	40	NC_008536.1	3168566-3168605	1	0.975
NC_008536_10	10.1\|6146974\|40\|NC_008536\|CRISPRCasFinder	6146974-6147013	40	NC_008536.1	3659600-3659639	1	0.975
NC_008536_10	10.1\|6146974\|40\|NC_008536\|CRISPRCasFinder	6146974-6147013	40	NC_008536.1	4220476-4220515	1	0.975
NC_008536_10	10.1\|6146974\|40\|NC_008536\|CRISPRCasFinder	6146974-6147013	40	NC_008536.1	5139950-5139989	1	0.975
NC_008536_10	10.1\|6146974\|40\|NC_008536\|CRISPRCasFinder	6146974-6147013	40	NC_008536.1	6652040-6652079	1	0.975
NC_008536_10	10.1\|6146974\|40\|NC_008536\|CRISPRCasFinder	6146974-6147013	40	NC_008536.1	7913701-7913740	1	0.975
NC_008536_10	10.1\|6146974\|40\|NC_008536\|CRISPRCasFinder	6146974-6147013	40	NC_008536.1	3298635-3298674	1	0.975
NC_008536_10	10.1\|6146974\|40\|NC_008536\|CRISPRCasFinder	6146974-6147013	40	NC_008536.1	4426330-4426369	1	0.975
NC_008536_10	10.1\|6146974\|40\|NC_008536\|CRISPRCasFinder	6146974-6147013	40	NC_008536.1	5655160-5655199	1	0.975
NC_008536_10	10.1\|6146974\|40\|NC_008536\|CRISPRCasFinder	6146974-6147013	40	NC_008536.1	5925140-5925179	1	0.975
NC_008536_10	10.1\|6146974\|40\|NC_008536\|CRISPRCasFinder	6146974-6147013	40	NC_008536.1	6651182-6651221	1	0.975
NC_008536_10	10.1\|6146974\|40\|NC_008536\|CRISPRCasFinder	6146974-6147013	40	NC_008536.1	9197628-9197667	1	0.975
NC_008536_10	10.1\|6146974\|40\|NC_008536\|CRISPRCasFinder	6146974-6147013	40	NC_008536.1	9214066-9214105	1	0.975
NC_008536_10	10.1\|6146974\|40\|NC_008536\|CRISPRCasFinder	6146974-6147013	40	NC_008536.1	9905445-9905484	1	0.975
NC_008536_11	11.1\|6187314\|43\|NC_008536\|CRISPRCasFinder	6187314-6187356	43	NC_008536.1	2143540-2143582	1	0.977
NC_008536_14	14.1\|9083729\|42\|NC_008536\|CRISPRCasFinder	9083729-9083770	42	NC_008536.1	4426330-4426371	1	0.976
NC_008536_14	14.1\|9083729\|42\|NC_008536\|CRISPRCasFinder	9083729-9083770	42	NC_008536.1	5655160-5655201	1	0.976
NC_008536_14	14.1\|9083729\|42\|NC_008536\|CRISPRCasFinder	9083729-9083770	42	NC_008536.1	5925140-5925181	1	0.976
NC_008536_14	14.1\|9083729\|42\|NC_008536\|CRISPRCasFinder	9083729-9083770	42	NC_008536.1	6651182-6651223	1	0.976
NC_008536_14	14.1\|9083729\|42\|NC_008536\|CRISPRCasFinder	9083729-9083770	42	NC_008536.1	9197628-9197669	1	0.976
NC_008536_14	14.1\|9083729\|42\|NC_008536\|CRISPRCasFinder	9083729-9083770	42	NC_008536.1	9214066-9214107	1	0.976
NC_008536_14	14.1\|9083729\|42\|NC_008536\|CRISPRCasFinder	9083729-9083770	42	NC_008536.1	9905445-9905486	1	0.976
NC_008536_14	14.1\|9083729\|42\|NC_008536\|CRISPRCasFinder	9083729-9083770	42	NC_008536.1	40821-40862	1	0.976
NC_008536_14	14.1\|9083729\|42\|NC_008536\|CRISPRCasFinder	9083729-9083770	42	NC_008536.1	2383303-2383344	1	0.976
NC_008536_14	14.1\|9083729\|42\|NC_008536\|CRISPRCasFinder	9083729-9083770	42	NC_008536.1	2578877-2578918	1	0.976
NC_008536_14	14.1\|9083729\|42\|NC_008536\|CRISPRCasFinder	9083729-9083770	42	NC_008536.1	2854248-2854289	1	0.976
NC_008536_14	14.1\|9083729\|42\|NC_008536\|CRISPRCasFinder	9083729-9083770	42	NC_008536.1	3168564-3168605	1	0.976
NC_008536_14	14.1\|9083729\|42\|NC_008536\|CRISPRCasFinder	9083729-9083770	42	NC_008536.1	3659598-3659639	1	0.976
NC_008536_14	14.1\|9083729\|42\|NC_008536\|CRISPRCasFinder	9083729-9083770	42	NC_008536.1	4220474-4220515	1	0.976
NC_008536_14	14.1\|9083729\|42\|NC_008536\|CRISPRCasFinder	9083729-9083770	42	NC_008536.1	6652038-6652079	1	0.976
NC_008536_14	14.1\|9083729\|42\|NC_008536\|CRISPRCasFinder	9083729-9083770	42	NC_008536.1	7913699-7913740	1	0.976
NC_008536_4	4.1\|2821045\|42\|NC_008536\|CRISPRCasFinder	2821045-2821086	42	NC_008536.1	40823-40864	2	0.952
NC_008536_4	4.1\|2821045\|42\|NC_008536\|CRISPRCasFinder	2821045-2821086	42	NC_008536.1	2383305-2383346	2	0.952
NC_008536_4	4.1\|2821045\|42\|NC_008536\|CRISPRCasFinder	2821045-2821086	42	NC_008536.1	2529225-2529266	2	0.952
NC_008536_4	4.1\|2821045\|42\|NC_008536\|CRISPRCasFinder	2821045-2821086	42	NC_008536.1	2578879-2578920	2	0.952
NC_008536_4	4.1\|2821045\|42\|NC_008536\|CRISPRCasFinder	2821045-2821086	42	NC_008536.1	2854250-2854291	2	0.952
NC_008536_4	4.1\|2821045\|42\|NC_008536\|CRISPRCasFinder	2821045-2821086	42	NC_008536.1	3168566-3168607	2	0.952
NC_008536_4	4.1\|2821045\|42\|NC_008536\|CRISPRCasFinder	2821045-2821086	42	NC_008536.1	3298633-3298674	2	0.952
NC_008536_4	4.1\|2821045\|42\|NC_008536\|CRISPRCasFinder	2821045-2821086	42	NC_008536.1	3659600-3659641	2	0.952
NC_008536_4	4.1\|2821045\|42\|NC_008536\|CRISPRCasFinder	2821045-2821086	42	NC_008536.1	4220476-4220517	2	0.952
NC_008536_4	4.1\|2821045\|42\|NC_008536\|CRISPRCasFinder	2821045-2821086	42	NC_008536.1	4426328-4426369	2	0.952
NC_008536_4	4.1\|2821045\|42\|NC_008536\|CRISPRCasFinder	2821045-2821086	42	NC_008536.1	5139950-5139991	2	0.952
NC_008536_4	4.1\|2821045\|42\|NC_008536\|CRISPRCasFinder	2821045-2821086	42	NC_008536.1	5655158-5655199	2	0.952
NC_008536_4	4.1\|2821045\|42\|NC_008536\|CRISPRCasFinder	2821045-2821086	42	NC_008536.1	5925138-5925179	2	0.952
NC_008536_4	4.1\|2821045\|42\|NC_008536\|CRISPRCasFinder	2821045-2821086	42	NC_008536.1	6651180-6651221	2	0.952
NC_008536_4	4.1\|2821045\|42\|NC_008536\|CRISPRCasFinder	2821045-2821086	42	NC_008536.1	6652040-6652081	2	0.952
NC_008536_4	4.1\|2821045\|42\|NC_008536\|CRISPRCasFinder	2821045-2821086	42	NC_008536.1	7913701-7913742	2	0.952
NC_008536_4	4.1\|2821045\|42\|NC_008536\|CRISPRCasFinder	2821045-2821086	42	NC_008536.1	9197626-9197667	2	0.952
NC_008536_4	4.1\|2821045\|42\|NC_008536\|CRISPRCasFinder	2821045-2821086	42	NC_008536.1	9214064-9214105	2	0.952
NC_008536_4	4.1\|2821045\|42\|NC_008536\|CRISPRCasFinder	2821045-2821086	42	NC_008536.1	9905443-9905484	2	0.952
NC_008536_10	10.1\|6146974\|40\|NC_008536\|CRISPRCasFinder	6146974-6147013	40	NC_008536.1	4317711-4317750	2	0.95
NC_008536_10	10.1\|6146974\|40\|NC_008536\|CRISPRCasFinder	6146974-6147013	40	NC_008536.1	8080594-8080633	2	0.95
NC_008536_10	10.1\|6146974\|40\|NC_008536\|CRISPRCasFinder	6146974-6147013	40	NC_008536.1	1804480-1804519	2	0.95
NC_008536_10	10.1\|6146974\|40\|NC_008536\|CRISPRCasFinder	6146974-6147013	40	NC_008536.1	2143540-2143579	2	0.95
NC_008536_10	10.1\|6146974\|40\|NC_008536\|CRISPRCasFinder	6146974-6147013	40	NC_008536.1	2529227-2529266	2	0.95
NC_008536_10	10.1\|6146974\|40\|NC_008536\|CRISPRCasFinder	6146974-6147013	40	NC_008536.1	2852165-2852204	2	0.95
NC_008536_10	10.1\|6146974\|40\|NC_008536\|CRISPRCasFinder	6146974-6147013	40	NC_008536.1	4826603-4826642	2	0.95
NC_008536_10	10.1\|6146974\|40\|NC_008536\|CRISPRCasFinder	6146974-6147013	40	NC_008536.1	4937316-4937355	2	0.95
NC_008536_11	11.1\|6187314\|43\|NC_008536\|CRISPRCasFinder	6187314-6187356	43	NC_008536.1	40820-40862	2	0.953
NC_008536_11	11.1\|6187314\|43\|NC_008536\|CRISPRCasFinder	6187314-6187356	43	NC_008536.1	2383302-2383344	2	0.953
NC_008536_11	11.1\|6187314\|43\|NC_008536\|CRISPRCasFinder	6187314-6187356	43	NC_008536.1	2578876-2578918	2	0.953
NC_008536_11	11.1\|6187314\|43\|NC_008536\|CRISPRCasFinder	6187314-6187356	43	NC_008536.1	2854247-2854289	2	0.953
NC_008536_11	11.1\|6187314\|43\|NC_008536\|CRISPRCasFinder	6187314-6187356	43	NC_008536.1	3168563-3168605	2	0.953
NC_008536_11	11.1\|6187314\|43\|NC_008536\|CRISPRCasFinder	6187314-6187356	43	NC_008536.1	3659597-3659639	2	0.953
NC_008536_11	11.1\|6187314\|43\|NC_008536\|CRISPRCasFinder	6187314-6187356	43	NC_008536.1	4220473-4220515	2	0.953
NC_008536_11	11.1\|6187314\|43\|NC_008536\|CRISPRCasFinder	6187314-6187356	43	NC_008536.1	4426330-4426372	2	0.953
NC_008536_11	11.1\|6187314\|43\|NC_008536\|CRISPRCasFinder	6187314-6187356	43	NC_008536.1	5655160-5655202	2	0.953
NC_008536_11	11.1\|6187314\|43\|NC_008536\|CRISPRCasFinder	6187314-6187356	43	NC_008536.1	5925140-5925182	2	0.953
NC_008536_11	11.1\|6187314\|43\|NC_008536\|CRISPRCasFinder	6187314-6187356	43	NC_008536.1	6651182-6651224	2	0.953
NC_008536_11	11.1\|6187314\|43\|NC_008536\|CRISPRCasFinder	6187314-6187356	43	NC_008536.1	6652037-6652079	2	0.953
NC_008536_11	11.1\|6187314\|43\|NC_008536\|CRISPRCasFinder	6187314-6187356	43	NC_008536.1	7913698-7913740	2	0.953
NC_008536_11	11.1\|6187314\|43\|NC_008536\|CRISPRCasFinder	6187314-6187356	43	NC_008536.1	9197628-9197670	2	0.953
NC_008536_11	11.1\|6187314\|43\|NC_008536\|CRISPRCasFinder	6187314-6187356	43	NC_008536.1	9214066-9214108	2	0.953
NC_008536_11	11.1\|6187314\|43\|NC_008536\|CRISPRCasFinder	6187314-6187356	43	NC_008536.1	9905445-9905487	2	0.953
NC_008536_14	14.1\|9083729\|42\|NC_008536\|CRISPRCasFinder	9083729-9083770	42	NC_008536.1	1804480-1804521	2	0.952
NC_008536_14	14.1\|9083729\|42\|NC_008536\|CRISPRCasFinder	9083729-9083770	42	NC_008536.1	2143540-2143581	2	0.952
NC_008536_14	14.1\|9083729\|42\|NC_008536\|CRISPRCasFinder	9083729-9083770	42	NC_008536.1	2529227-2529268	2	0.952
NC_008536_14	14.1\|9083729\|42\|NC_008536\|CRISPRCasFinder	9083729-9083770	42	NC_008536.1	2852165-2852206	2	0.952
NC_008536_14	14.1\|9083729\|42\|NC_008536\|CRISPRCasFinder	9083729-9083770	42	NC_008536.1	4826603-4826644	2	0.952
NC_008536_14	14.1\|9083729\|42\|NC_008536\|CRISPRCasFinder	9083729-9083770	42	NC_008536.1	4937316-4937357	2	0.952
NC_008536_14	14.1\|9083729\|42\|NC_008536\|CRISPRCasFinder	9083729-9083770	42	NC_008536.1	4317709-4317750	2	0.952
NC_008536_14	14.1\|9083729\|42\|NC_008536\|CRISPRCasFinder	9083729-9083770	42	NC_008536.1	5122713-5122754	2	0.952
NC_008536_14	14.1\|9083729\|42\|NC_008536\|CRISPRCasFinder	9083729-9083770	42	NC_008536.1	5843603-5843644	2	0.952
NC_008536_14	14.1\|9083729\|42\|NC_008536\|CRISPRCasFinder	9083729-9083770	42	NC_008536.1	8080592-8080633	2	0.952

1. spacer 10.1|6146974|40|NC_008536|CRISPRCasFinder matches to position: 40823-40862, mismatch: 1, identity: 0.975

tcgcgatggcgctgcgcgccatttaaggggatgaaaaacc	CRISPR spacer
tcgcgatggcgctgcgcgccatttaaggggatgaaaaccc	Protospacer
************************************* **

2. spacer 10.1|6146974|40|NC_008536|CRISPRCasFinder matches to position: 2383305-2383344, mismatch: 1, identity: 0.975

tcgcgatggcgctgcgcgccatttaaggggatgaaaaacc	CRISPR spacer
tcgcgatggcgctgcgcgccatttaaggggatgaaaaccc	Protospacer
************************************* **

3. spacer 10.1|6146974|40|NC_008536|CRISPRCasFinder matches to position: 2578879-2578918, mismatch: 1, identity: 0.975

tcgcgatggcgctgcgcgccatttaaggggatgaaaaacc	CRISPR spacer
tcgcgatggcgctgcgcgccatttaaggggatgaaaaccc	Protospacer
************************************* **

4. spacer 10.1|6146974|40|NC_008536|CRISPRCasFinder matches to position: 2854250-2854289, mismatch: 1, identity: 0.975

tcgcgatggcgctgcgcgccatttaaggggatgaaaaacc	CRISPR spacer
tcgcgatggcgctgcgcgccatttaaggggatgaaaaccc	Protospacer
************************************* **

5. spacer 10.1|6146974|40|NC_008536|CRISPRCasFinder matches to position: 3168566-3168605, mismatch: 1, identity: 0.975

tcgcgatggcgctgcgcgccatttaaggggatgaaaaacc	CRISPR spacer
tcgcgatggcgctgcgcgccatttaaggggatgaaaaccc	Protospacer
************************************* **

6. spacer 10.1|6146974|40|NC_008536|CRISPRCasFinder matches to position: 3659600-3659639, mismatch: 1, identity: 0.975

tcgcgatggcgctgcgcgccatttaaggggatgaaaaacc	CRISPR spacer
tcgcgatggcgctgcgcgccatttaaggggatgaaaaccc	Protospacer
************************************* **

7. spacer 10.1|6146974|40|NC_008536|CRISPRCasFinder matches to position: 4220476-4220515, mismatch: 1, identity: 0.975

tcgcgatggcgctgcgcgccatttaaggggatgaaaaacc	CRISPR spacer
tcgcgatggcgctgcgcgccatttaaggggatgaaaaccc	Protospacer
************************************* **

8. spacer 10.1|6146974|40|NC_008536|CRISPRCasFinder matches to position: 5139950-5139989, mismatch: 1, identity: 0.975

tcgcgatggcgctgcgcgccatttaaggggatgaaaaacc	CRISPR spacer
tcgcgatggcgctgcgcgccatttaaggggatgaaaaccc	Protospacer
************************************* **

9. spacer 10.1|6146974|40|NC_008536|CRISPRCasFinder matches to position: 6652040-6652079, mismatch: 1, identity: 0.975

tcgcgatggcgctgcgcgccatttaaggggatgaaaaacc	CRISPR spacer
tcgcgatggcgctgcgcgccatttaaggggatgaaaaccc	Protospacer
************************************* **

10. spacer 10.1|6146974|40|NC_008536|CRISPRCasFinder matches to position: 7913701-7913740, mismatch: 1, identity: 0.975

tcgcgatggcgctgcgcgccatttaaggggatgaaaaacc	CRISPR spacer
tcgcgatggcgctgcgcgccatttaaggggatgaaaaccc	Protospacer
************************************* **

11. spacer 10.1|6146974|40|NC_008536|CRISPRCasFinder matches to position: 3298635-3298674, mismatch: 1, identity: 0.975

tcgcgatggcgctgcgcgccatttaaggggatgaaaaacc	CRISPR spacer
tcgcgatggcgctgcgcgccatttaaggggatgaaaaccc	Protospacer
************************************* **

12. spacer 10.1|6146974|40|NC_008536|CRISPRCasFinder matches to position: 4426330-4426369, mismatch: 1, identity: 0.975

tcgcgatggcgctgcgcgccatttaaggggatgaaaaacc	CRISPR spacer
tcgcgatggcgctgcgcgccatttaaggggatgaaaaccc	Protospacer
************************************* **

13. spacer 10.1|6146974|40|NC_008536|CRISPRCasFinder matches to position: 5655160-5655199, mismatch: 1, identity: 0.975

tcgcgatggcgctgcgcgccatttaaggggatgaaaaacc	CRISPR spacer
tcgcgatggcgctgcgcgccatttaaggggatgaaaaccc	Protospacer
************************************* **

14. spacer 10.1|6146974|40|NC_008536|CRISPRCasFinder matches to position: 5925140-5925179, mismatch: 1, identity: 0.975

tcgcgatggcgctgcgcgccatttaaggggatgaaaaacc	CRISPR spacer
tcgcgatggcgctgcgcgccatttaaggggatgaaaaccc	Protospacer
************************************* **

15. spacer 10.1|6146974|40|NC_008536|CRISPRCasFinder matches to position: 6651182-6651221, mismatch: 1, identity: 0.975

tcgcgatggcgctgcgcgccatttaaggggatgaaaaacc	CRISPR spacer
tcgcgatggcgctgcgcgccatttaaggggatgaaaaccc	Protospacer
************************************* **

16. spacer 10.1|6146974|40|NC_008536|CRISPRCasFinder matches to position: 9197628-9197667, mismatch: 1, identity: 0.975

tcgcgatggcgctgcgcgccatttaaggggatgaaaaacc	CRISPR spacer
tcgcgatggcgctgcgcgccatttaaggggatgaaaaccc	Protospacer
************************************* **

17. spacer 10.1|6146974|40|NC_008536|CRISPRCasFinder matches to position: 9214066-9214105, mismatch: 1, identity: 0.975

tcgcgatggcgctgcgcgccatttaaggggatgaaaaacc	CRISPR spacer
tcgcgatggcgctgcgcgccatttaaggggatgaaaaccc	Protospacer
************************************* **

18. spacer 10.1|6146974|40|NC_008536|CRISPRCasFinder matches to position: 9905445-9905484, mismatch: 1, identity: 0.975

tcgcgatggcgctgcgcgccatttaaggggatgaaaaacc	CRISPR spacer
tcgcgatggcgctgcgcgccatttaaggggatgaaaaccc	Protospacer
************************************* **

19. spacer 11.1|6187314|43|NC_008536|CRISPRCasFinder matches to position: 2143540-2143582, mismatch: 1, identity: 0.977

tcgcgatggcgctgcgagccatttagggggatgaaaacccctt	CRISPR spacer
tcgcgatggcgctgcgcgccatttagggggatgaaaacccctt	Protospacer
**************** **************************

20. spacer 14.1|9083729|42|NC_008536|CRISPRCasFinder matches to position: 4426330-4426371, mismatch: 1, identity: 0.976

aggggttttcatccctttaaatggcgcgcagcgccatcgcga	CRISPR spacer
aggggttttcatccccttaaatggcgcgcagcgccatcgcga	Protospacer
***************.**************************

21. spacer 14.1|9083729|42|NC_008536|CRISPRCasFinder matches to position: 5655160-5655201, mismatch: 1, identity: 0.976

aggggttttcatccctttaaatggcgcgcagcgccatcgcga	CRISPR spacer
aggggttttcatccccttaaatggcgcgcagcgccatcgcga	Protospacer
***************.**************************

22. spacer 14.1|9083729|42|NC_008536|CRISPRCasFinder matches to position: 5925140-5925181, mismatch: 1, identity: 0.976

aggggttttcatccctttaaatggcgcgcagcgccatcgcga	CRISPR spacer
aggggttttcatccccttaaatggcgcgcagcgccatcgcga	Protospacer
***************.**************************

23. spacer 14.1|9083729|42|NC_008536|CRISPRCasFinder matches to position: 6651182-6651223, mismatch: 1, identity: 0.976

aggggttttcatccctttaaatggcgcgcagcgccatcgcga	CRISPR spacer
aggggttttcatccccttaaatggcgcgcagcgccatcgcga	Protospacer
***************.**************************

24. spacer 14.1|9083729|42|NC_008536|CRISPRCasFinder matches to position: 9197628-9197669, mismatch: 1, identity: 0.976

aggggttttcatccctttaaatggcgcgcagcgccatcgcga	CRISPR spacer
aggggttttcatccccttaaatggcgcgcagcgccatcgcga	Protospacer
***************.**************************

25. spacer 14.1|9083729|42|NC_008536|CRISPRCasFinder matches to position: 9214066-9214107, mismatch: 1, identity: 0.976

aggggttttcatccctttaaatggcgcgcagcgccatcgcga	CRISPR spacer
aggggttttcatccccttaaatggcgcgcagcgccatcgcga	Protospacer
***************.**************************

26. spacer 14.1|9083729|42|NC_008536|CRISPRCasFinder matches to position: 9905445-9905486, mismatch: 1, identity: 0.976

aggggttttcatccctttaaatggcgcgcagcgccatcgcga	CRISPR spacer
aggggttttcatccccttaaatggcgcgcagcgccatcgcga	Protospacer
***************.**************************

27. spacer 14.1|9083729|42|NC_008536|CRISPRCasFinder matches to position: 40821-40862, mismatch: 1, identity: 0.976

aggggttttcatccctttaaatggcgcgcagcgccatcgcga	CRISPR spacer
aggggttttcatccccttaaatggcgcgcagcgccatcgcga	Protospacer
***************.**************************

28. spacer 14.1|9083729|42|NC_008536|CRISPRCasFinder matches to position: 2383303-2383344, mismatch: 1, identity: 0.976

aggggttttcatccctttaaatggcgcgcagcgccatcgcga	CRISPR spacer
aggggttttcatccccttaaatggcgcgcagcgccatcgcga	Protospacer
***************.**************************

29. spacer 14.1|9083729|42|NC_008536|CRISPRCasFinder matches to position: 2578877-2578918, mismatch: 1, identity: 0.976

aggggttttcatccctttaaatggcgcgcagcgccatcgcga	CRISPR spacer
aggggttttcatccccttaaatggcgcgcagcgccatcgcga	Protospacer
***************.**************************

30. spacer 14.1|9083729|42|NC_008536|CRISPRCasFinder matches to position: 2854248-2854289, mismatch: 1, identity: 0.976

aggggttttcatccctttaaatggcgcgcagcgccatcgcga	CRISPR spacer
aggggttttcatccccttaaatggcgcgcagcgccatcgcga	Protospacer
***************.**************************

31. spacer 14.1|9083729|42|NC_008536|CRISPRCasFinder matches to position: 3168564-3168605, mismatch: 1, identity: 0.976

aggggttttcatccctttaaatggcgcgcagcgccatcgcga	CRISPR spacer
aggggttttcatccccttaaatggcgcgcagcgccatcgcga	Protospacer
***************.**************************

32. spacer 14.1|9083729|42|NC_008536|CRISPRCasFinder matches to position: 3659598-3659639, mismatch: 1, identity: 0.976

aggggttttcatccctttaaatggcgcgcagcgccatcgcga	CRISPR spacer
aggggttttcatccccttaaatggcgcgcagcgccatcgcga	Protospacer
***************.**************************

33. spacer 14.1|9083729|42|NC_008536|CRISPRCasFinder matches to position: 4220474-4220515, mismatch: 1, identity: 0.976

aggggttttcatccctttaaatggcgcgcagcgccatcgcga	CRISPR spacer
aggggttttcatccccttaaatggcgcgcagcgccatcgcga	Protospacer
***************.**************************

34. spacer 14.1|9083729|42|NC_008536|CRISPRCasFinder matches to position: 6652038-6652079, mismatch: 1, identity: 0.976

aggggttttcatccctttaaatggcgcgcagcgccatcgcga	CRISPR spacer
aggggttttcatccccttaaatggcgcgcagcgccatcgcga	Protospacer
***************.**************************

35. spacer 14.1|9083729|42|NC_008536|CRISPRCasFinder matches to position: 7913699-7913740, mismatch: 1, identity: 0.976

aggggttttcatccctttaaatggcgcgcagcgccatcgcga	CRISPR spacer
aggggttttcatccccttaaatggcgcgcagcgccatcgcga	Protospacer
***************.**************************

36. spacer 4.1|2821045|42|NC_008536|CRISPRCasFinder matches to position: 40823-40864, mismatch: 2, identity: 0.952

ggattttcatccccttaaatggcgcacagcgccatcgcgaca	CRISPR spacer
gggttttcatccccttaaatggcgcgcagcgccatcgcgaca	Protospacer
**.**********************.****************

37. spacer 4.1|2821045|42|NC_008536|CRISPRCasFinder matches to position: 2383305-2383346, mismatch: 2, identity: 0.952

ggattttcatccccttaaatggcgcacagcgccatcgcgaca	CRISPR spacer
gggttttcatccccttaaatggcgcgcagcgccatcgcgaca	Protospacer
**.**********************.****************

38. spacer 4.1|2821045|42|NC_008536|CRISPRCasFinder matches to position: 2529225-2529266, mismatch: 2, identity: 0.952

ggattttcatccccttaaatggcgcacagcgccatcgcgaca	CRISPR spacer
gggttttcatccccttaaatggcgctcagcgccatcgcgaca	Protospacer
**.********************** ****************

39. spacer 4.1|2821045|42|NC_008536|CRISPRCasFinder matches to position: 2578879-2578920, mismatch: 2, identity: 0.952

ggattttcatccccttaaatggcgcacagcgccatcgcgaca	CRISPR spacer
gggttttcatccccttaaatggcgcgcagcgccatcgcgaca	Protospacer
**.**********************.****************

40. spacer 4.1|2821045|42|NC_008536|CRISPRCasFinder matches to position: 2854250-2854291, mismatch: 2, identity: 0.952

ggattttcatccccttaaatggcgcacagcgccatcgcgaca	CRISPR spacer
gggttttcatccccttaaatggcgcgcagcgccatcgcgaca	Protospacer
**.**********************.****************

41. spacer 4.1|2821045|42|NC_008536|CRISPRCasFinder matches to position: 3168566-3168607, mismatch: 2, identity: 0.952

ggattttcatccccttaaatggcgcacagcgccatcgcgaca	CRISPR spacer
gggttttcatccccttaaatggcgcgcagcgccatcgcgaca	Protospacer
**.**********************.****************

42. spacer 4.1|2821045|42|NC_008536|CRISPRCasFinder matches to position: 3298633-3298674, mismatch: 2, identity: 0.952

ggattttcatccccttaaatggcgcacagcgccatcgcgaca	CRISPR spacer
gggttttcatccccttaaatggcgcgcagcgccatcgcgaca	Protospacer
**.**********************.****************

43. spacer 4.1|2821045|42|NC_008536|CRISPRCasFinder matches to position: 3659600-3659641, mismatch: 2, identity: 0.952

ggattttcatccccttaaatggcgcacagcgccatcgcgaca	CRISPR spacer
gggttttcatccccttaaatggcgcgcagcgccatcgcgaca	Protospacer
**.**********************.****************

44. spacer 4.1|2821045|42|NC_008536|CRISPRCasFinder matches to position: 4220476-4220517, mismatch: 2, identity: 0.952

ggattttcatccccttaaatggcgcacagcgccatcgcgaca	CRISPR spacer
gggttttcatccccttaaatggcgcgcagcgccatcgcgaca	Protospacer
**.**********************.****************

45. spacer 4.1|2821045|42|NC_008536|CRISPRCasFinder matches to position: 4426328-4426369, mismatch: 2, identity: 0.952

ggattttcatccccttaaatggcgcacagcgccatcgcgaca	CRISPR spacer
gggttttcatccccttaaatggcgcgcagcgccatcgcgaca	Protospacer
**.**********************.****************

46. spacer 4.1|2821045|42|NC_008536|CRISPRCasFinder matches to position: 5139950-5139991, mismatch: 2, identity: 0.952

ggattttcatccccttaaatggcgcacagcgccatcgcgaca	CRISPR spacer
gggttttcatccccttaaatggcgcgcagcgccatcgcgaca	Protospacer
**.**********************.****************

47. spacer 4.1|2821045|42|NC_008536|CRISPRCasFinder matches to position: 5655158-5655199, mismatch: 2, identity: 0.952

ggattttcatccccttaaatggcgcacagcgccatcgcgaca	CRISPR spacer
gggttttcatccccttaaatggcgcgcagcgccatcgcgaca	Protospacer
**.**********************.****************

48. spacer 4.1|2821045|42|NC_008536|CRISPRCasFinder matches to position: 5925138-5925179, mismatch: 2, identity: 0.952

ggattttcatccccttaaatggcgcacagcgccatcgcgaca	CRISPR spacer
gggttttcatccccttaaatggcgcgcagcgccatcgcgaca	Protospacer
**.**********************.****************

49. spacer 4.1|2821045|42|NC_008536|CRISPRCasFinder matches to position: 6651180-6651221, mismatch: 2, identity: 0.952

ggattttcatccccttaaatggcgcacagcgccatcgcgaca	CRISPR spacer
gggttttcatccccttaaatggcgcgcagcgccatcgcgaca	Protospacer
**.**********************.****************

50. spacer 4.1|2821045|42|NC_008536|CRISPRCasFinder matches to position: 6652040-6652081, mismatch: 2, identity: 0.952

ggattttcatccccttaaatggcgcacagcgccatcgcgaca	CRISPR spacer
gggttttcatccccttaaatggcgcgcagcgccatcgcgaca	Protospacer
**.**********************.****************

51. spacer 4.1|2821045|42|NC_008536|CRISPRCasFinder matches to position: 7913701-7913742, mismatch: 2, identity: 0.952

ggattttcatccccttaaatggcgcacagcgccatcgcgaca	CRISPR spacer
gggttttcatccccttaaatggcgcgcagcgccatcgcgaca	Protospacer
**.**********************.****************

52. spacer 4.1|2821045|42|NC_008536|CRISPRCasFinder matches to position: 9197626-9197667, mismatch: 2, identity: 0.952

ggattttcatccccttaaatggcgcacagcgccatcgcgaca	CRISPR spacer
gggttttcatccccttaaatggcgcgcagcgccatcgcgaca	Protospacer
**.**********************.****************

53. spacer 4.1|2821045|42|NC_008536|CRISPRCasFinder matches to position: 9214064-9214105, mismatch: 2, identity: 0.952

ggattttcatccccttaaatggcgcacagcgccatcgcgaca	CRISPR spacer
gggttttcatccccttaaatggcgcgcagcgccatcgcgaca	Protospacer
**.**********************.****************

54. spacer 4.1|2821045|42|NC_008536|CRISPRCasFinder matches to position: 9905443-9905484, mismatch: 2, identity: 0.952

ggattttcatccccttaaatggcgcacagcgccatcgcgaca	CRISPR spacer
gggttttcatccccttaaatggcgcgcagcgccatcgcgaca	Protospacer
**.**********************.****************

55. spacer 10.1|6146974|40|NC_008536|CRISPRCasFinder matches to position: 4317711-4317750, mismatch: 2, identity: 0.95

tcgcgatggcgctgcgcgccatttaaggggatgaaaaacc	CRISPR spacer
tctcgatggcgctgcgcgccatttaaggggatgaaaaccc	Protospacer
** ********************************** **

56. spacer 10.1|6146974|40|NC_008536|CRISPRCasFinder matches to position: 8080594-8080633, mismatch: 2, identity: 0.95

tcgcgatggcgctgcgcgccatttaaggggatgaaaaacc	CRISPR spacer
tcgcgatggcgctgcgcgccatttaagggaatgaaaaccc	Protospacer
*****************************.******* **

57. spacer 10.1|6146974|40|NC_008536|CRISPRCasFinder matches to position: 1804480-1804519, mismatch: 2, identity: 0.95

tcgcgatggcgctgcgcgccatttaaggggatgaaaaacc	CRISPR spacer
tcgcgatggcgctgcgcgtcatttaaggggatgaaaaccc	Protospacer
******************.****************** **

58. spacer 10.1|6146974|40|NC_008536|CRISPRCasFinder matches to position: 2143540-2143579, mismatch: 2, identity: 0.95

tcgcgatggcgctgcgcgccatttaaggggatgaaaaacc	CRISPR spacer
tcgcgatggcgctgcgcgccatttagggggatgaaaaccc	Protospacer
*************************.*********** **

59. spacer 10.1|6146974|40|NC_008536|CRISPRCasFinder matches to position: 2529227-2529266, mismatch: 2, identity: 0.95

tcgcgatggcgctgcgcgccatttaaggggatgaaaaacc	CRISPR spacer
tcgcgatggcgctgagcgccatttaaggggatgaaaaccc	Protospacer
************** ********************** **

60. spacer 10.1|6146974|40|NC_008536|CRISPRCasFinder matches to position: 2852165-2852204, mismatch: 2, identity: 0.95

tcgcgatggcgctgcgcgccatttaaggggatgaaaaacc	CRISPR spacer
tcgcgatggcgctgcgcgccatttaagggaatgaaaaccc	Protospacer
*****************************.******* **

61. spacer 10.1|6146974|40|NC_008536|CRISPRCasFinder matches to position: 4826603-4826642, mismatch: 2, identity: 0.95

tcgcgatggcgctgcgcgccatttaaggggatgaaaaacc	CRISPR spacer
tcgcgatggcgctgcgcgcgatttaaggggatgaaaaccc	Protospacer
******************* ***************** **

62. spacer 10.1|6146974|40|NC_008536|CRISPRCasFinder matches to position: 4937316-4937355, mismatch: 2, identity: 0.95

tcgcgatggcgctgcgcgccatttaaggggatgaaaaacc	CRISPR spacer
tcgcgatggcgctgcgcgccattcaaggggatgaaaaccc	Protospacer
***********************.************* **

63. spacer 11.1|6187314|43|NC_008536|CRISPRCasFinder matches to position: 40820-40862, mismatch: 2, identity: 0.953

tcgcgatggcgctgcgagccatttagggggatgaaaacccctt	CRISPR spacer
tcgcgatggcgctgcgcgccatttaaggggatgaaaacccctt	Protospacer
**************** ********.*****************

64. spacer 11.1|6187314|43|NC_008536|CRISPRCasFinder matches to position: 2383302-2383344, mismatch: 2, identity: 0.953

tcgcgatggcgctgcgagccatttagggggatgaaaacccctt	CRISPR spacer
tcgcgatggcgctgcgcgccatttaaggggatgaaaacccctt	Protospacer
**************** ********.*****************

65. spacer 11.1|6187314|43|NC_008536|CRISPRCasFinder matches to position: 2578876-2578918, mismatch: 2, identity: 0.953

tcgcgatggcgctgcgagccatttagggggatgaaaacccctt	CRISPR spacer
tcgcgatggcgctgcgcgccatttaaggggatgaaaacccctt	Protospacer
**************** ********.*****************

66. spacer 11.1|6187314|43|NC_008536|CRISPRCasFinder matches to position: 2854247-2854289, mismatch: 2, identity: 0.953

tcgcgatggcgctgcgagccatttagggggatgaaaacccctt	CRISPR spacer
tcgcgatggcgctgcgcgccatttaaggggatgaaaacccctt	Protospacer
**************** ********.*****************

67. spacer 11.1|6187314|43|NC_008536|CRISPRCasFinder matches to position: 3168563-3168605, mismatch: 2, identity: 0.953

tcgcgatggcgctgcgagccatttagggggatgaaaacccctt	CRISPR spacer
tcgcgatggcgctgcgcgccatttaaggggatgaaaacccctt	Protospacer
**************** ********.*****************

68. spacer 11.1|6187314|43|NC_008536|CRISPRCasFinder matches to position: 3659597-3659639, mismatch: 2, identity: 0.953

tcgcgatggcgctgcgagccatttagggggatgaaaacccctt	CRISPR spacer
tcgcgatggcgctgcgcgccatttaaggggatgaaaacccctt	Protospacer
**************** ********.*****************

69. spacer 11.1|6187314|43|NC_008536|CRISPRCasFinder matches to position: 4220473-4220515, mismatch: 2, identity: 0.953

tcgcgatggcgctgcgagccatttagggggatgaaaacccctt	CRISPR spacer
tcgcgatggcgctgcgcgccatttaaggggatgaaaacccctt	Protospacer
**************** ********.*****************

70. spacer 11.1|6187314|43|NC_008536|CRISPRCasFinder matches to position: 4426330-4426372, mismatch: 2, identity: 0.953

tcgcgatggcgctgcgagccatttagggggatgaaaacccctt	CRISPR spacer
tcgcgatggcgctgcgcgccatttaaggggatgaaaacccctt	Protospacer
**************** ********.*****************

71. spacer 11.1|6187314|43|NC_008536|CRISPRCasFinder matches to position: 5655160-5655202, mismatch: 2, identity: 0.953

tcgcgatggcgctgcgagccatttagggggatgaaaacccctt	CRISPR spacer
tcgcgatggcgctgcgcgccatttaaggggatgaaaacccctt	Protospacer
**************** ********.*****************

72. spacer 11.1|6187314|43|NC_008536|CRISPRCasFinder matches to position: 5925140-5925182, mismatch: 2, identity: 0.953

tcgcgatggcgctgcgagccatttagggggatgaaaacccctt	CRISPR spacer
tcgcgatggcgctgcgcgccatttaaggggatgaaaacccctt	Protospacer
**************** ********.*****************

73. spacer 11.1|6187314|43|NC_008536|CRISPRCasFinder matches to position: 6651182-6651224, mismatch: 2, identity: 0.953

tcgcgatggcgctgcgagccatttagggggatgaaaacccctt	CRISPR spacer
tcgcgatggcgctgcgcgccatttaaggggatgaaaacccctt	Protospacer
**************** ********.*****************

74. spacer 11.1|6187314|43|NC_008536|CRISPRCasFinder matches to position: 6652037-6652079, mismatch: 2, identity: 0.953

tcgcgatggcgctgcgagccatttagggggatgaaaacccctt	CRISPR spacer
tcgcgatggcgctgcgcgccatttaaggggatgaaaacccctt	Protospacer
**************** ********.*****************

75. spacer 11.1|6187314|43|NC_008536|CRISPRCasFinder matches to position: 7913698-7913740, mismatch: 2, identity: 0.953

tcgcgatggcgctgcgagccatttagggggatgaaaacccctt	CRISPR spacer
tcgcgatggcgctgcgcgccatttaaggggatgaaaacccctt	Protospacer
**************** ********.*****************

76. spacer 11.1|6187314|43|NC_008536|CRISPRCasFinder matches to position: 9197628-9197670, mismatch: 2, identity: 0.953

tcgcgatggcgctgcgagccatttagggggatgaaaacccctt	CRISPR spacer
tcgcgatggcgctgcgcgccatttaaggggatgaaaacccctt	Protospacer
**************** ********.*****************

77. spacer 11.1|6187314|43|NC_008536|CRISPRCasFinder matches to position: 9214066-9214108, mismatch: 2, identity: 0.953

tcgcgatggcgctgcgagccatttagggggatgaaaacccctt	CRISPR spacer
tcgcgatggcgctgcgcgccatttaaggggatgaaaacccctt	Protospacer
**************** ********.*****************

78. spacer 11.1|6187314|43|NC_008536|CRISPRCasFinder matches to position: 9905445-9905487, mismatch: 2, identity: 0.953

tcgcgatggcgctgcgagccatttagggggatgaaaacccctt	CRISPR spacer
tcgcgatggcgctgcgcgccatttaaggggatgaaaacccctt	Protospacer
**************** ********.*****************

79. spacer 14.1|9083729|42|NC_008536|CRISPRCasFinder matches to position: 1804480-1804521, mismatch: 2, identity: 0.952

aggggttttcatccctttaaatggcgcgcagcgccatcgcga	CRISPR spacer
aggggttttcatccccttaaatgacgcgcagcgccatcgcga	Protospacer
***************.*******.******************

80. spacer 14.1|9083729|42|NC_008536|CRISPRCasFinder matches to position: 2143540-2143581, mismatch: 2, identity: 0.952

aggggttttcatccctttaaatggcgcgcagcgccatcgcga	CRISPR spacer
aggggttttcatccccctaaatggcgcgcagcgccatcgcga	Protospacer
***************..*************************

81. spacer 14.1|9083729|42|NC_008536|CRISPRCasFinder matches to position: 2529227-2529268, mismatch: 2, identity: 0.952

aggggttttcatccctttaaatggcgcgcagcgccatcgcga	CRISPR spacer
aggggttttcatccccttaaatggcgctcagcgccatcgcga	Protospacer
***************.*********** **************

82. spacer 14.1|9083729|42|NC_008536|CRISPRCasFinder matches to position: 2852165-2852206, mismatch: 2, identity: 0.952

aggggttttcatccctttaaatggcgcgcagcgccatcgcga	CRISPR spacer
aggggttttcattcccttaaatggcgcgcagcgccatcgcga	Protospacer
************.**.**************************

83. spacer 14.1|9083729|42|NC_008536|CRISPRCasFinder matches to position: 4826603-4826644, mismatch: 2, identity: 0.952

aggggttttcatccctttaaatggcgcgcagcgccatcgcga	CRISPR spacer
aggggttttcatccccttaaatcgcgcgcagcgccatcgcga	Protospacer
***************.****** *******************

84. spacer 14.1|9083729|42|NC_008536|CRISPRCasFinder matches to position: 4937316-4937357, mismatch: 2, identity: 0.952

aggggttttcatccctttaaatggcgcgcagcgccatcgcga	CRISPR spacer
aggggttttcatccccttgaatggcgcgcagcgccatcgcga	Protospacer
***************.**.***********************

85. spacer 14.1|9083729|42|NC_008536|CRISPRCasFinder matches to position: 4317709-4317750, mismatch: 2, identity: 0.952

aggggttttcatccctttaaatggcgcgcagcgccatcgcga	CRISPR spacer
aggggttttcatccccttaaatggcgcgcagcgccatcgaga	Protospacer
***************.*********************** **

86. spacer 14.1|9083729|42|NC_008536|CRISPRCasFinder matches to position: 5122713-5122754, mismatch: 2, identity: 0.952

aggggttttcatccctttaaatggcgcgcagcgccatcgcga	CRISPR spacer
agcggttttcatccccttaaatggcgcgcagcgccatcgcga	Protospacer
** ************.**************************

87. spacer 14.1|9083729|42|NC_008536|CRISPRCasFinder matches to position: 5843603-5843644, mismatch: 2, identity: 0.952

aggggttttcatccctttaaatggcgcgcagcgccatcgcga	CRISPR spacer
agcggttttcatccccttaaatggcgcgcagcgccatcgcga	Protospacer
** ************.**************************

88. spacer 14.1|9083729|42|NC_008536|CRISPRCasFinder matches to position: 8080592-8080633, mismatch: 2, identity: 0.952

aggggttttcatccctttaaatggcgcgcagcgccatcgcga	CRISPR spacer
aggggttttcattcccttaaatggcgcgcagcgccatcgcga	Protospacer
************.**.**************************

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

736506 : 797760

environmental_halophage(14.29%)

transposase,tRNA,integrase

attL 785394:785416|attR 800945:800967

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_011682381.1\|736506_737622_-\|tRNA	tRNA 2-thiouridine(34) synthase MnmA	NA	NA	NA	NA
WP_041858880.1\|737614_738769_-	cysteine desulfurase	Q2XUY6	environmental_halophage	6.4e-33	30.6
WP_011682383.1\|738786_739575_+	SAM-dependent chlorinase/fluorinase	NA	NA	NA	NA
WP_011682384.1\|739634_740420_+	daunorubicin resistance protein DrrA family ABC transporter ATP-binding protein	W6JKT0	Anomala_cuprea_entomopoxvirus	1.3e-16	25.4
WP_011682385.1\|740419_741166_+	ABC transporter permease	NA	NA	NA	NA
WP_157675092.1\|741162_741792_+	TetR family transcriptional regulator	NA	NA	NA	NA
WP_011682387.1\|741766_743836_-	acylase	NA	NA	NA	NA
WP_011682388.1\|743832_745497_-	dihydroxy-acid dehydratase	NA	NA	NA	NA
WP_041857319.1\|745511_745895_-	metallopeptidase family protein	NA	NA	NA	NA
WP_011682390.1\|746312_747977_+	hypothetical protein	NA	NA	NA	NA
WP_157675093.1\|748102_748240_+	hypothetical protein	NA	NA	NA	NA
WP_011682391.1\|748348_748585_+	hypothetical protein	NA	NA	NA	NA
WP_041857321.1\|748829_749057_+	hypothetical protein	NA	NA	NA	NA
WP_011682393.1\|749303_750638_-	glycosyltransferase	NA	NA	NA	NA
WP_157675094.1\|750741_751203_+	hypothetical protein	NA	NA	NA	NA
WP_011682395.1\|751345_752839_+	hypothetical protein	NA	NA	NA	NA
WP_157675095.1\|752835_756072_+	glycosyltransferase	NA	NA	NA	NA
WP_011682397.1\|756139_757132_+	class I SAM-dependent methyltransferase	NA	NA	NA	NA
WP_041857324.1\|757189_757933_+	class I SAM-dependent methyltransferase	NA	NA	NA	NA
WP_011682399.1\|757965_760155_-	hypothetical protein	NA	NA	NA	NA
WP_157675096.1\|760290_763701_-	glycosyltransferase	NA	NA	NA	NA
WP_157675097.1\|763706_764066_+	hypothetical protein	NA	NA	NA	NA
WP_011682402.1\|764528_766163_+	NAD+ synthase	A0A2L0UZF5	Agrobacterium_phage	4.4e-80	34.8
WP_011682403.1\|766165_767509_+	UDP-glucose/GDP-mannose dehydrogenase family protein	A0A0K0KW09	Prochlorococcus_phage	9.4e-44	33.3
WP_011682404.1\|767592_769380_+	FkbM family methyltransferase	NA	NA	NA	NA
WP_049872932.1\|770004_770463_+	hypothetical protein	A0A2L1IVB6	Escherichia_phage	1.5e-09	37.0
WP_157675098.1\|770647_772096_+	hypothetical protein	NA	NA	NA	NA
WP_011682407.1\|772319_786320_+	hypothetical protein	NA	NA	NA	NA
785394:785416	attL	NA	NA	NA	NA
WP_041857326.1\|786512_790988_+	hypothetical protein	NA	NA	NA	NA
WP_011682409.1\|791081_791381_+	hypothetical protein	NA	NA	NA	NA
WP_157675099.1\|791411_791540_-	hypothetical protein	NA	NA	NA	NA
WP_011682410.1\|791669_792425_+\|integrase	tyrosine-type recombinase/integrase	NA	NA	NA	NA
WP_011682411.1\|792475_793714_+\|integrase	tyrosine-type recombinase/integrase	A0A2H4JAA2	uncultured_Caudovirales_phage	1.7e-07	30.4
WP_011682412.1\|794638_795637_+\|integrase	tyrosine-type recombinase/integrase	NA	NA	NA	NA
WP_049872933.1\|795633_796230_-\|integrase	tyrosine-type recombinase/integrase	NA	NA	NA	NA
WP_011682414.1\|796570_796933_+\|transposase	transposase	NA	NA	NA	NA
WP_011682415.1\|796929_797760_+\|transposase	IS3 family transposase	U5P429	Shigella_phage	5.8e-36	36.6
800945:800967	attR	NA	NA	NA	NA

DBSCAN-SWA_2

4118342 : 4191597

Pandoravirus(20.0%)

transposase,protease,integrase

attL 4188319:4188350|attR 4191689:4191720

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_157675348.1\|4118342_4119404_+\|protease	M48 family metalloprotease	NA	NA	NA	NA
WP_011684994.1\|4119479_4120571_-	acetate kinase	NA	NA	NA	NA
WP_011684995.1\|4120590_4121544_-	DoxX family protein	NA	NA	NA	NA
WP_011684996.1\|4121556_4122087_+	hypothetical protein	NA	NA	NA	NA
WP_041857859.1\|4122164_4122344_-	Flp family type IVb pilin	NA	NA	NA	NA
WP_011684997.1\|4122497_4123826_-	hypothetical protein	NA	NA	NA	NA
WP_011684998.1\|4123822_4125826_-	oligopeptide transporter, OPT family	NA	NA	NA	NA
WP_011683708.1\|4126376_4127684_-\|transposase	ISNCY family transposase	NA	NA	NA	NA
WP_011684999.1\|4127849_4128440_+	sigma-70 family RNA polymerase sigma factor	NA	NA	NA	NA
WP_011685000.1\|4128426_4130979_+	protein kinase	A0A0B5J6A8	Pandoravirus	1.7e-14	32.3
WP_041857860.1\|4131074_4131797_+	hypothetical protein	NA	NA	NA	NA
WP_011685002.1\|4131845_4132553_+	TIGR03435 family protein	NA	NA	NA	NA
WP_011685003.1\|4132637_4133222_+	TetR/AcrR family transcriptional regulator	NA	NA	NA	NA
WP_041857861.1\|4133414_4133708_+	hypothetical protein	NA	NA	NA	NA
WP_011685005.1\|4133757_4134591_+	class I SAM-dependent methyltransferase	NA	NA	NA	NA
WP_011685006.1\|4134646_4135156_+	hypothetical protein	NA	NA	NA	NA
WP_011685007.1\|4135608_4136592_+	aldo/keto reductase	NA	NA	NA	NA
WP_157675349.1\|4136595_4138041_+	cytochrome C	NA	NA	NA	NA
WP_011685009.1\|4138344_4139163_+	sel1 repeat family protein	NA	NA	NA	NA
WP_011685010.1\|4139167_4140406_+	hypothetical protein	NA	NA	NA	NA
WP_157675350.1\|4140614_4141406_+	FHA domain-containing protein	NA	NA	NA	NA
WP_011685012.1\|4141398_4142292_+	serine/threonine-protein phosphatase	NA	NA	NA	NA
WP_011685013.1\|4142296_4143988_+	serine/threonine protein kinase	A0A1B1IUU3	uncultured_Mediterranean_phage	2.7e-11	27.9
WP_011685014.1\|4144079_4147169_+	penicillin-binding protein	NA	NA	NA	NA
WP_011685015.1\|4147165_4147948_+	FHA domain-containing protein	NA	NA	NA	NA
WP_011685016.1\|4147931_4148726_-	hypothetical protein	NA	NA	NA	NA
WP_011685017.1\|4148985_4152597_+	TonB-dependent receptor	NA	NA	NA	NA
WP_011685018.1\|4152773_4153835_-	ribosome small subunit-dependent GTPase A	NA	NA	NA	NA
WP_011685019.1\|4153930_4154716_+	aldolase	NA	NA	NA	NA
WP_011685020.1\|4154712_4155729_+	sugar phosphate isomerase/epimerase	NA	NA	NA	NA
WP_011685021.1\|4155735_4155975_+	hypothetical protein	NA	NA	NA	NA
WP_011685022.1\|4156017_4156434_+	hypothetical protein	NA	NA	NA	NA
WP_011685023.1\|4156451_4157120_-	hypothetical protein	NA	NA	NA	NA
WP_011685024.1\|4157295_4159740_-	ABC transporter permease	NA	NA	NA	NA
WP_049873097.1\|4159795_4160326_-	hypothetical protein	NA	NA	NA	NA
WP_041859454.1\|4160453_4160930_+	VOC family protein	NA	NA	NA	NA
WP_011685028.1\|4161618_4163451_+	response regulator	Q8QKV7	Ectocarpus_siliculosus_virus	6.8e-37	30.0
WP_011685029.1\|4163728_4164376_+	hypothetical protein	NA	NA	NA	NA
WP_011685030.1\|4164495_4165029_-	TIM barrel protein	NA	NA	NA	NA
WP_011685031.1\|4165029_4165518_-	DinB family protein	NA	NA	NA	NA
WP_011685032.1\|4165565_4166891_-	hypothetical protein	NA	NA	NA	NA
WP_011685033.1\|4167442_4175755_-	Ig domain-containing protein	NA	NA	NA	NA
WP_041857865.1\|4176124_4176475_+	PadR family transcriptional regulator	NA	NA	NA	NA
WP_011685035.1\|4176478_4179202_+	ABC transporter permease	NA	NA	NA	NA
WP_011685036.1\|4179416_4180043_+	hypothetical protein	NA	NA	NA	NA
WP_041857867.1\|4181372_4182152_-	4-carboxymuconolactone decarboxylase	NA	NA	NA	NA
WP_011685039.1\|4182148_4182391_-	4-oxalocrotonate tautomerase	NA	NA	NA	NA
WP_011685040.1\|4182390_4182789_-	DUF2255 family protein	NA	NA	NA	NA
WP_011685041.1\|4182811_4183828_-	zinc-dependent alcohol dehydrogenase family protein	NA	NA	NA	NA
WP_011685042.1\|4183837_4184833_-	aldo/keto reductase	NA	NA	NA	NA
WP_085952965.1\|4184835_4185255_-	hypothetical protein	NA	NA	NA	NA
WP_011685044.1\|4185439_4186390_+	AraC family transcriptional regulator	NA	NA	NA	NA
WP_011685045.1\|4186899_4188093_-\|transposase	IS91 family transposase	NA	NA	NA	NA
4188319:4188350	attL	NA	NA	NA	NA
WP_011685046.1\|4188435_4189674_+\|integrase	tyrosine-type recombinase/integrase	A0A2H4JAA2	uncultured_Caudovirales_phage	2.2e-07	30.4
WP_011685047.1\|4189670_4190615_+\|integrase	tyrosine-type recombinase/integrase	NA	NA	NA	NA
WP_011685048.1\|4190598_4191597_+\|integrase	site-specific integrase	U5JA40	Bacillus_phage	4.9e-05	23.6
4191689:4191720	attR	NA	NA	NA	NA

DBSCAN-SWA_3

5943694 : 6012553

Only_Syngen_Nebraska_virus(20.0%)

transposase,integrase

attL 5987632:5987649|attR 6022362:6022379

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_011686406.1\|5943694_5944933_+\|integrase	tyrosine-type recombinase/integrase	NA	NA	NA	NA
WP_011686407.1\|5945172_5945517_-	STAS domain-containing protein	NA	NA	NA	NA
WP_041858140.1\|5945539_5946496_-	DUF72 domain-containing protein	NA	NA	NA	NA
WP_011686409.1\|5946489_5948322_-	gamma-glutamyltransferase family protein	NA	NA	NA	NA
WP_041859760.1\|5948616_5948967_+	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_011686411.1\|5949028_5951569_+	ABC transporter permease	NA	NA	NA	NA
WP_011686412.1\|5951625_5954283_-	ABC transporter permease	NA	NA	NA	NA
WP_011686413.1\|5954287_5954638_-	PadR family transcriptional regulator	NA	NA	NA	NA
WP_011686414.1\|5954686_5956261_-	amidohydrolase family protein	NA	NA	NA	NA
WP_157675469.1\|5956273_5956429_-	hypothetical protein	NA	NA	NA	NA
WP_011686415.1\|5956553_5957588_+	Ldh family oxidoreductase	NA	NA	NA	NA
WP_011686416.1\|5957598_5958471_+	lipoyl synthase	NA	NA	NA	NA
WP_011686417.1\|5958673_5959543_+	hypothetical protein	NA	NA	NA	NA
WP_011686418.1\|5959567_5960443_+	DMT family transporter	NA	NA	NA	NA
WP_011686419.1\|5960520_5961150_+	hypothetical protein	NA	NA	NA	NA
WP_011686420.1\|5961504_5962398_-	MOSC domain-containing protein	NA	NA	NA	NA
WP_041858143.1\|5962446_5963052_-	transcription elongation factor GreB	NA	NA	NA	NA
WP_011686422.1\|5963207_5964524_-	Gfo/Idh/MocA family oxidoreductase	NA	NA	NA	NA
WP_011686423.1\|5964549_5965506_-	D-2-hydroxyacid dehydrogenase	A0A1J0F959	Only_Syngen_Nebraska_virus	3.0e-28	29.5
WP_011686424.1\|5965506_5966106_-	4'-phosphopantetheinyl transferase superfamily protein	NA	NA	NA	NA
WP_011686425.1\|5966102_5968088_-	glycosyltransferase	NA	NA	NA	NA
WP_157675922.1\|5968344_5969115_-	glycosyltransferase	NA	NA	NA	NA
WP_049873199.1\|5969550_5971569_-	HAD-IIIC family phosphatase	NA	NA	NA	NA
WP_011686428.1\|5971591_5971897_+	isochorismate lyase	NA	NA	NA	NA
WP_157675470.1\|5971907_5972510_-	DUF664 domain-containing protein	NA	NA	NA	NA
WP_011686430.1\|5972506_5973052_-	SRPBCC family protein	NA	NA	NA	NA
WP_011686431.1\|5973048_5973606_-	hypothetical protein	NA	NA	NA	NA
WP_011686432.1\|5973602_5973926_-	PadR family transcriptional regulator	NA	NA	NA	NA
WP_011686433.1\|5973976_5975380_+	aminopeptidase P family protein	NA	NA	NA	NA
WP_011686434.1\|5975449_5977429_-	M13 family metallopeptidase	E3T4I7	Cafeteria_roenbergensis_virus	1.2e-79	31.3
WP_011686435.1\|5977459_5978164_-	orotidine-5'-phosphate decarboxylase	NA	NA	NA	NA
WP_083783834.1\|5978160_5979183_-	selenide, water dikinase SelD	NA	NA	NA	NA
WP_011686437.1\|5979207_5980608_+	peptidase C45	NA	NA	NA	NA
WP_063720758.1\|5980608_5983905_-	TonB-dependent receptor	NA	NA	NA	NA
WP_011686439.1\|5984118_5985882_-	hypothetical protein	NA	NA	NA	NA
WP_011686440.1\|5985973_5986933_-	hypothetical protein	NA	NA	NA	NA
WP_049873200.1\|5987032_5987431_+	hypothetical protein	NA	NA	NA	NA
WP_011686442.1\|5987427_5988021_-	hypothetical protein	NA	NA	NA	NA
5987632:5987649	attL	NA	NA	NA	NA
WP_011684349.1\|5988851_5989784_-\|transposase	IS3 family transposase	A0A1P8CWQ3	Bacillus_phage	4.7e-34	32.5
WP_011683270.1\|5989780_5990137_-\|transposase	transposase	NA	NA	NA	NA
WP_011686444.1\|5990218_5990944_-	TIGR03435 family protein	NA	NA	NA	NA
WP_011686445.1\|5990949_5992698_-	tetratricopeptide repeat protein	NA	NA	NA	NA
WP_011686446.1\|5992756_5996746_-	carboxypeptidase regulatory-like domain-containing protein	NA	NA	NA	NA
WP_049873201.1\|5997076_5997721_-	methyltransferase domain-containing protein	NA	NA	NA	NA
WP_011686448.1\|5997984_5999169_-	6-phosphofructokinase	NA	NA	NA	NA
WP_011686449.1\|5999311_5999653_-	response regulator	NA	NA	NA	NA
WP_041859770.1\|5999848_6000952_-	hypothetical protein	NA	NA	NA	NA
WP_157675923.1\|6001093_6001618_+	sigma-70 family RNA polymerase sigma factor	NA	NA	NA	NA
WP_011686452.1\|6001607_6002141_+	hypothetical protein	NA	NA	NA	NA
WP_011686453.1\|6002130_6002697_-	OmpH family outer membrane protein	NA	NA	NA	NA
WP_011686454.1\|6002789_6003980_+	O-antigen ligase family protein	NA	NA	NA	NA
WP_083784136.1\|6004157_6005414_-\|transposase	IS701-like element ISSus1 family transposase	NA	NA	NA	NA
WP_049873202.1\|6005607_6006684_+	TIGR03118 family protein	A0A2K9KZ30	Tupanvirus	2.5e-23	28.5
WP_011686457.1\|6006763_6008242_+	hypothetical protein	NA	NA	NA	NA
WP_011686458.1\|6008403_6009576_+	Gfo/Idh/MocA family oxidoreductase	NA	NA	NA	NA
WP_011686459.1\|6009590_6010016_+	cupin domain-containing protein	NA	NA	NA	NA
WP_011686460.1\|6010209_6011520_-\|transposase	transposase	NA	NA	NA	NA
WP_157675924.1\|6011680_6012553_-\|integrase	tyrosine-type recombinase/integrase	A0A1P8DJJ6	Virus_Rctr41k	8.8e-19	26.3
6022362:6022379	attR	NA	NA	NA	NA

DBSCAN-SWA_4

7586557 : 7657261

Acidithiobacillus_phage(20.0%)

transposase,integrase

attL 7586391:7586437|attR 7659494:7659540

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
7586391:7586437	attL	NA	NA	NA	NA
WP_011687724.1\|7586557_7588114_+\|transposase	IS21 family transposase	K4I413	Acidithiobacillus_phage	9.2e-136	49.6
WP_157675601.1\|7589201_7589402_+	hypothetical protein	NA	NA	NA	NA
WP_011687727.1\|7590174_7590879_+	hypothetical protein	NA	NA	NA	NA
WP_157675602.1\|7591075_7591279_-	hypothetical protein	NA	NA	NA	NA
WP_011687729.1\|7591718_7592768_-	hypothetical protein	NA	NA	NA	NA
WP_041858412.1\|7592864_7593062_+	hypothetical protein	NA	NA	NA	NA
WP_011687731.1\|7593548_7594028_+	response regulator	NA	NA	NA	NA
WP_157675963.1\|7594097_7594226_+	DUF2934 domain-containing protein	NA	NA	NA	NA
WP_011687732.1\|7594365_7594845_+	hypothetical protein	NA	NA	NA	NA
WP_011687733.1\|7595346_7595673_-	PQQ-binding-like beta-propeller repeat protein	NA	NA	NA	NA
WP_157675603.1\|7595909_7596074_+	hypothetical protein	NA	NA	NA	NA
WP_011687734.1\|7596784_7597627_-\|transposase	IS3 family transposase	U5P429	Shigella_phage	1.6e-33	34.8
WP_011682718.1\|7597623_7597983_-\|transposase	transposase	NA	NA	NA	NA
WP_049873300.1\|7598733_7599390_-	TetR/AcrR family transcriptional regulator	NA	NA	NA	NA
WP_011687737.1\|7600639_7601389_+	SDR family oxidoreductase	A0A0M4JSW6	Mollivirus	2.6e-11	27.9
WP_011687738.1\|7601469_7602258_+	SDR family oxidoreductase	NA	NA	NA	NA
WP_041858414.1\|7603042_7603303_-	hypothetical protein	NA	NA	NA	NA
WP_083783929.1\|7604977_7607335_+	CRTAC1 family protein	NA	NA	NA	NA
WP_011687743.1\|7607338_7609174_+	beta-propeller fold lactonase family protein	NA	NA	NA	NA
WP_011687744.1\|7609170_7610292_+	ligand-binding sensor domain-containing protein	NA	NA	NA	NA
WP_011687745.1\|7610288_7610777_+	endoribonuclease L-PSP	NA	NA	NA	NA
WP_011687746.1\|7610779_7612603_+	amino acid ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_011687747.1\|7612865_7614134_-	hypothetical protein	NA	NA	NA	NA
WP_011687748.1\|7614375_7617756_+	TonB-dependent receptor	NA	NA	NA	NA
WP_157675964.1\|7617800_7619429_-	CRTAC1 family protein	NA	NA	NA	NA
WP_011687750.1\|7619461_7620496_-	tetratricopeptide repeat protein	NA	NA	NA	NA
WP_011687751.1\|7622879_7624229_-	hypothetical protein	NA	NA	NA	NA
WP_157675604.1\|7624225_7624897_-	hypothetical protein	NA	NA	NA	NA
WP_011687753.1\|7624938_7626228_-	amidohydrolase family protein	NA	NA	NA	NA
WP_049873303.1\|7626231_7626648_-	amidohydrolase family protein	NA	NA	NA	NA
WP_157675605.1\|7626832_7627192_-	hypothetical protein	NA	NA	NA	NA
WP_011687757.1\|7628105_7628732_-	hypothetical protein	NA	NA	NA	NA
WP_011687758.1\|7629091_7629700_+	hypothetical protein	NA	NA	NA	NA
WP_157675606.1\|7630063_7630393_+	hypothetical protein	NA	NA	NA	NA
WP_041858422.1\|7631771_7632656_-\|integrase	tyrosine-type recombinase/integrase	A0A1P8DJJ6	Virus_Rctr41k	6.0e-23	29.7
WP_011687762.1\|7633239_7634262_+	phosphodiester glycosidase family protein	NA	NA	NA	NA
WP_011687763.1\|7635032_7636103_-	hypothetical protein	NA	NA	NA	NA
WP_011687764.1\|7636105_7636669_-	hypothetical protein	NA	NA	NA	NA
WP_011687765.1\|7637194_7637602_+	hypothetical protein	NA	NA	NA	NA
WP_011687766.1\|7637821_7639036_-	methyltransferase domain-containing protein	NA	NA	NA	NA
WP_011687767.1\|7640182_7641004_+	PEP-CTERM sorting domain-containing protein	NA	NA	NA	NA
WP_011687768.1\|7641618_7643124_-	M28 family peptidase	NA	NA	NA	NA
WP_011687769.1\|7643364_7644879_-	ABC transporter ATP-binding protein	W5SAS9	Pithovirus	2.7e-07	26.6
WP_011687770.1\|7644875_7645805_-	ABC transporter permease	NA	NA	NA	NA
WP_011687771.1\|7645794_7646847_-	ABC transporter permease	NA	NA	NA	NA
WP_011687772.1\|7646846_7647953_-	BMP family ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_011687773.1\|7647949_7649356_-	AtzE family amidohydrolase	NA	NA	NA	NA
WP_011687774.1\|7649352_7649892_-	oxalurate catabolism protein HpxZ	NA	NA	NA	NA
WP_011687775.1\|7649901_7652532_-	TonB-dependent receptor	NA	NA	NA	NA
WP_083783931.1\|7653337_7654393_-\|transposase	IS91 family transposase	NA	NA	NA	NA
WP_157675607.1\|7654414_7654828_+	hypothetical protein	NA	NA	NA	NA
WP_011687778.1\|7654809_7655175_+	IS66 family insertion sequence element accessory protein TnpB	NA	NA	NA	NA
WP_157675965.1\|7655228_7656116_+	DUF4338 domain-containing protein	NA	NA	NA	NA
WP_083783933.1\|7656112_7657261_+\|transposase	transposase	NA	NA	NA	NA
7659494:7659540	attR	NA	NA	NA	NA

DBSCAN-SWA_5

8518862 : 8554752

Escherichia_phage(33.33%)

transposase,integrase

attL 8521128:8521148|attR 8531927:8531947

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_011688432.1\|8518862_8519798_+\|integrase	site-specific integrase	A0A0K0N6I5	Gordonia_phage	4.1e-06	31.5
WP_011688433.1\|8520247_8520934_-	curculin domain-containing protein	NA	NA	NA	NA
8521128:8521148	attL	NA	NA	NA	NA
WP_041858533.1\|8521450_8521816_+	hypothetical protein	NA	NA	NA	NA
WP_157675661.1\|8522772_8524605_+	hypothetical protein	NA	NA	NA	NA
WP_011688436.1\|8525788_8526811_-	glycosyl hydrolase	NA	NA	NA	NA
WP_157675662.1\|8526850_8528806_+	hypothetical protein	NA	NA	NA	NA
WP_011688438.1\|8529323_8529656_-	hypothetical protein	NA	NA	NA	NA
WP_011688439.1\|8529958_8531050_-\|integrase	site-specific integrase	NA	NA	NA	NA
WP_157675663.1\|8531046_8531622_-\|integrase	tyrosine-type recombinase/integrase	NA	NA	NA	NA
WP_041858535.1\|8532007_8532400_-	hypothetical protein	NA	NA	NA	NA
8531927:8531947	attR	NA	NA	NA	NA
WP_157675664.1\|8533042_8533927_+	hypothetical protein	NA	NA	NA	NA
WP_011688443.1\|8534161_8534875_-\|transposase	IS6 family transposase	A0A077SL39	Escherichia_phage	3.1e-54	49.3
WP_011688444.1\|8535078_8535357_-	hypothetical protein	NA	NA	NA	NA
WP_011688445.1\|8535375_8535783_-	hypothetical protein	NA	NA	NA	NA
WP_157675979.1\|8535779_8536442_-	AAA family ATPase	U5N3V8	Enterobacteria_phage	2.8e-57	52.2
WP_157675665.1\|8536551_8537793_-\|transposase	IS21 family transposase	A0A2L1IVA1	Escherichia_phage	5.4e-38	35.7
WP_157675666.1\|8537813_8538347_+	hypothetical protein	NA	NA	NA	NA
WP_011688449.1\|8538379_8539009_+	hypothetical protein	NA	NA	NA	NA
WP_157675667.1\|8539093_8539219_-	PEP-CTERM sorting domain-containing protein	NA	NA	NA	NA
WP_041858538.1\|8540605_8540794_+	hypothetical protein	NA	NA	NA	NA
WP_011688452.1\|8541266_8543423_-	DUF11 domain-containing protein	NA	NA	NA	NA
WP_011688454.1\|8544481_8545864_+	MFS transporter	NA	NA	NA	NA
WP_157675668.1\|8545824_8546865_+	aldo/keto reductase	NA	NA	NA	NA
WP_011688457.1\|8548839_8549331_+	hypothetical protein	NA	NA	NA	NA
WP_041858544.1\|8550289_8550499_+	hypothetical protein	NA	NA	NA	NA
WP_011688459.1\|8551286_8551565_-	hypothetical protein	NA	NA	NA	NA
WP_011688460.1\|8551869_8552190_-	PAS sensor domain-containing protein	NA	NA	NA	NA
WP_049873353.1\|8552283_8553213_-	hypothetical protein	A0A076GD42	Sinorhizobium_phage	2.6e-24	29.7
WP_011682415.1\|8553921_8554752_-\|transposase	IS3 family transposase	U5P429	Shigella_phage	5.8e-36	36.6

DBSCAN-SWA_6

9545563 : 9574169

Escherichia_phage(60.0%)

transposase,integrase

attL 9529563:9529578|attR 9564860:9564875

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
9529563:9529578	attL	NA	NA	NA	NA
WP_011689228.1\|9545563_9546277_+\|transposase	IS6-like element ISSus3 family transposase	A0A077SL39	Escherichia_phage	2.1e-55	50.2
WP_157675741.1\|9546855_9547128_+	hypothetical protein	NA	NA	NA	NA
WP_157675742.1\|9547221_9547563_+	response regulator	NA	NA	NA	NA
WP_041858694.1\|9547581_9547800_+	hypothetical protein	NA	NA	NA	NA
WP_011689230.1\|9547853_9548129_-	hypothetical protein	NA	NA	NA	NA
WP_157675743.1\|9548762_9549032_+	hypothetical protein	NA	NA	NA	NA
WP_011689233.1\|9549135_9549429_-	hypothetical protein	NA	NA	NA	NA
WP_157675744.1\|9550162_9550474_-	ATP-dependent DNA ligase	NA	NA	NA	NA
WP_049873400.1\|9550500_9550842_-\|transposase	IS6 family transposase	A0A077SL39	Escherichia_phage	2.8e-21	48.0
WP_157676008.1\|9550971_9552498_-	phosphoesterase	A0A1V0SD32	Indivirus	3.2e-88	40.5
WP_041858698.1\|9552720_9553170_-	PEP-CTERM sorting domain-containing protein	NA	NA	NA	NA
WP_157675745.1\|9553405_9554137_-	PEP-CTERM sorting domain-containing protein	NA	NA	NA	NA
WP_157675746.1\|9556156_9556882_+\|transposase	transposase	K4HZD4	Acidithiobacillus_phage	6.1e-58	49.2
WP_041858700.1\|9557260_9557836_-\|integrase,transposase	DDE-type integrase/transposase/recombinase	NA	NA	NA	NA
WP_157675747.1\|9558826_9559015_-	hypothetical protein	NA	NA	NA	NA
WP_011683390.1\|9560148_9560895_-	hypothetical protein	NA	NA	NA	NA
WP_157675179.1\|9561337_9561649_-	hypothetical protein	NA	NA	NA	NA
WP_011689240.1\|9565282_9565852_+	sigma-70 family RNA polymerase sigma factor	NA	NA	NA	NA
9564860:9564875	attR	NA	NA	NA	NA
WP_011689241.1\|9566381_9567095_-\|transposase	IS6 family transposase	A0A077SL39	Escherichia_phage	2.6e-53	48.2
WP_157675748.1\|9567485_9568223_-	hypothetical protein	NA	NA	NA	NA
WP_041858704.1\|9568799_9569000_-	hypothetical protein	NA	NA	NA	NA
WP_011689242.1\|9569752_9570031_+	hypothetical protein	NA	NA	NA	NA
WP_011689243.1\|9570587_9571106_+	PEP-CTERM sorting domain-containing protein	NA	NA	NA	NA
WP_157675749.1\|9572999_9574169_+\|transposase	IS630 family transposase	NA	NA	NA	NA

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. NC_008536

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CRISPR-Cas detection and classification

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Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection