CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NC_008595	Mycobacterium avium 104, complete genome	8 crisprs	cas3,csa3,DinG,DEDDh,cas4,WYL	2	11	388	1

Results visualization

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CRISPR-Cas detection and classification

Crispr_ID: NC_008595_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_008595_1

279270-280041

Orphan

I-E

Consensus_repeat	Method
TGCTCCCCGCGCAAGCGGGGATGA	PILER-CR
TGCTCCCCGCGCAAGCGGGGATGA	CRISPRCasFinder
TGCTCCCCGCGCAAGCGGGGATGAACC	CRT

12 spacers

The CRISPR arrays of NC_008595_1

>merge|NC_008595|1|279270-280041|PILER-CR,CRISPRCasFinder,CRT
TGCTCCCCGCGTAAGCGGGGATGAACCGGTCGGTCACTGCGGTGGTGTCCTGTGCATGCTCCTGCTCCCCGCGCAAGCGGGGATGAACCTCCCAGGCGGACGCAGTGCCAGGGATGGCGAGTATGCTCCCCGCGCAAGCGGGGATGAACCCGAGGCCGTCGCGGAGGCCTTGACCGACCCCGATATGCTCCCCGCGCAAGCGGGGATGAACCGCGCACCTCAGCTGCTGTGCTGCGTGAGCGCGTCATATGCTCCCCGCGCAAGCGGGGATGAACCCCTGCACCAGTCGATCCACTGCGACGTGCGCAGCATGCTCCCCGCGCAAGCGGGGATGAACCCATCCCAGGTCAGGAAGTCTGCTCCCCGCGTAAGATGCTCCCCGCGCAAGCGGGGATGAACCGGGCCTGTTGCTCATCGGCCCGCCGCGCTCGGGCATGCTCCCCGCGCAAGCGGGGATGAACCGCCGATACCGGGCTTGGCATCCGTGCCGTACTGCTGCTCCCCGCGCAAGCGGGGATGACCCCGTGCCCGGTGGAGGAACCACCTCTCCCCCCACATGCTCCCCGCGCAAGCGGGGATGAACCGGCCGCAGAGGAGGCCGTCACCGCGGCGAAGACCTGCTCCCCGCGCAAGCGGGGATGAACCCCTCCGATCCAGGTACCGCGTCCGGAAGATGTGGCCTGCTCCCCGCGTAAGCGGGGATGACCCCCCCCGTCTGCAGCGCAACGGTTCCTACTGCACCTCCTGCTCCCCGCGCAAGCGGGGATGAACC

>NC_008595|1|1|279270-280038|PILER-CR
TGCTCCCCGCGTAAGCGGGGATGA	ACCGGTCGGTCACTGCGGTGGTGTCCTGTGCATGCTCC
TGCTCCCCGCGCAAGCGGGGATGA	ACCTCCCAGGCGGACGCAGTGCCAGGGATGGCGAGTA
TGCTCCCCGCGCAAGCGGGGATGA	ACCCGAGGCCGTCGCGGAGGCCTTGACCGACCCCGATA
TGCTCCCCGCGCAAGCGGGGATGA	ACCGCGCACCTCAGCTGCTGTGCTGCGTGAGCGCGTCATA
TGCTCCCCGCGCAAGCGGGGATGA	ACCCCTGCACCAGTCGATCCACTGCGACGTGCGCAGCA
TGCTCCCCGCGCAAGCGGGGATGA	ACCCATCCCAGGTCAGGAAGTCTGCTCCCCGCGTAAGA
TGCTCCCCGCGCAAGCGGGGATGA	ACCGGGCCTGTTGCTCATCGGCCCGCCGCGCTCGGGCA
TGCTCCCCGCGCAAGCGGGGATGA	ACCGCCGATACCGGGCTTGGCATCCGTGCCGTACTGC
TGCTCCCCGCGCAAGCGGGGATGA	CCCCGTGCCCGGTGGAGGAACCACCTCTCCCCCCACA
TGCTCCCCGCGCAAGCGGGGATGA	ACCGGCCGCAGAGGAGGCCGTCACCGCGGCGAAGACC
TGCTCCCCGCGCAAGCGGGGATGA	ACCCCTCCGATCCAGGTACCGCGTCCGGAAGATGTGGCC
TGCTCCCCGCGTAAGCGGGGATGA	CCCCCCCCGTCTGCAGCGCAACGGTTCCTACTGCACCTCC
TGCTCCCCGCGCAAGCGGGGATGA

>NC_008595|1|1|279270-280038|CRISPRCasFinder
TGCTCCCCGCGTAAGCGGGGATGA	ACCGGTCGGTCACTGCGGTGGTGTCCTGTGCATGCTCC
TGCTCCCCGCGCAAGCGGGGATGA	ACCTCCCAGGCGGACGCAGTGCCAGGGATGGCGAGTA
TGCTCCCCGCGCAAGCGGGGATGA	ACCCGAGGCCGTCGCGGAGGCCTTGACCGACCCCGATA
TGCTCCCCGCGCAAGCGGGGATGA	ACCGCGCACCTCAGCTGCTGTGCTGCGTGAGCGCGTCATA
TGCTCCCCGCGCAAGCGGGGATGA	ACCCCTGCACCAGTCGATCCACTGCGACGTGCGCAGCA
TGCTCCCCGCGCAAGCGGGGATGA	ACCCATCCCAGGTCAGGAAGTCTGCTCCCCGCGTAAGA
TGCTCCCCGCGCAAGCGGGGATGA	ACCGGGCCTGTTGCTCATCGGCCCGCCGCGCTCGGGCA
TGCTCCCCGCGCAAGCGGGGATGA	ACCGCCGATACCGGGCTTGGCATCCGTGCCGTACTGC
TGCTCCCCGCGCAAGCGGGGATGA	CCCCGTGCCCGGTGGAGGAACCACCTCTCCCCCCACA
TGCTCCCCGCGCAAGCGGGGATGA	ACCGGCCGCAGAGGAGGCCGTCACCGCGGCGAAGACC
TGCTCCCCGCGCAAGCGGGGATGA	ACCCCTCCGATCCAGGTACCGCGTCCGGAAGATGTGGCC
TGCTCCCCGCGTAAGCGGGGATGA	CCCCCCCCGTCTGCAGCGCAACGGTTCCTACTGCACCTCC
TGCTCCCCGCGCAAGCGGGGATGA

>NC_008595|1|1|279270-280041|CRT
TGCTCCCCGCGTAAGCGGGGATGAACC	GGTCGGTCACTGCGGTGGTGTCCTGTGCATGCTCC
TGCTCCCCGCGCAAGCGGGGATGAACC	TCCCAGGCGGACGCAGTGCCAGGGATGGCGAGTA
TGCTCCCCGCGCAAGCGGGGATGAACC	CGAGGCCGTCGCGGAGGCCTTGACCGACCCCGATA
TGCTCCCCGCGCAAGCGGGGATGAACC	GCGCACCTCAGCTGCTGTGCTGCGTGAGCGCGTCATA
TGCTCCCCGCGCAAGCGGGGATGAACC	CCTGCACCAGTCGATCCACTGCGACGTGCGCAGCA
TGCTCCCCGCGCAAGCGGGGATGAACC	CATCCCAGGTCAGGAAGTCTGCTCCCCGCGTAAGA
TGCTCCCCGCGCAAGCGGGGATGAACC	GGGCCTGTTGCTCATCGGCCCGCCGCGCTCGGGCA
TGCTCCCCGCGCAAGCGGGGATGAACC	GCCGATACCGGGCTTGGCATCCGTGCCGTACTGC
TGCTCCCCGCGCAAGCGGGGATGACCC	CGTGCCCGGTGGAGGAACCACCTCTCCCCCCACA
TGCTCCCCGCGCAAGCGGGGATGAACC	GGCCGCAGAGGAGGCCGTCACCGCGGCGAAGACC
TGCTCCCCGCGCAAGCGGGGATGAACC	CCTCCGATCCAGGTACCGCGTCCGGAAGATGTGGCC
TGCTCCCCGCGTAAGCGGGGATGACCC	CCCCCGTCTGCAGCGCAACGGTTCCTACTGCACCTCC
TGCTCCCCGCGCAAGCGGGGATGAACC

Protein	Signature genes	Signature genes Name	Protein_function
NC_008595.1\|WP_033722258.1\|273382_275530_-\|site-specific-DNA-methyltransferase	unknown	unknown	gnl\|CDD\|334588
NC_008595.1\|WP_011723458.1\|286608_286875_+\|glutaredoxin-family-protein	unknown	unknown	gnl\|CDD\|239274
NC_008595.1\|WP_011723446.1\|275690_276152_+\|prevent-host-death-protein	unknown	unknown	unknown
NC_008595.1\|WP_011723443.1\|270361_270778_-\|hypothetical-protein	unknown	unknown	unknown
NC_008595.1\|WP_011723444.1\|270791_273383_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|368155
NC_008595.1\|WP_011723442.1\|270076_270274_-\|helix-turn-helix-domain-containing-protein	unknown	unknown	gnl\|CDD\|378935
NC_008595.1\|WP_011723459.1\|286871_287255_+\|helix-turn-helix-domain-containing-protein	unknown	unknown	gnl\|CDD\|378935
NC_008595.1\|WP_085989534.1\|269780_270074_+\|helix-turn-helix-transcriptional-regulator	unknown	unknown	gnl\|CDD\|238045
NC_008595.1\|WP_033722259.1\|280866_281202_+\|hypothetical-protein	unknown	unknown	unknown
NC_008595.1\|WP_155267846.1\|278016_278979_-\|hypothetical-protein	unknown	unknown	unknown
NC_008595.1\|WP_011723460.1\|287282_289778_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|223021
NC_008595.1\|WP_011723454.1\|281198_283997_+\|bifunctional-DNA-primase/polymerase	unknown	unknown	gnl\|CDD\|240129
NC_008595.1\|WP_011723462.1\|290358_291492_+\|site-specific-integrase	unknown	unknown	gnl\|CDD\|271180
NC_008595.1\|WP_011723457.1\|285973_286585_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|340813
NC_008595.1\|WP_155267847.1\|285513_285789_+\|carnitine-racemase	unknown	unknown	unknown
NC_008595.1\|WP_011723447.1\|276154_276499_+\|hypothetical-protein	unknown	unknown	unknown
NC_008595.1\|WP_011723451.1\|278975_279179_-\|hypothetical-protein	unknown	unknown	unknown
NC_008595.1\|WP_011723448.1\|276508_277969_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|236090
NC_008595.1\|WP_011723455.1\|284491_285316_-\|hypothetical-protein	unknown	unknown	unknown
NC_008595.1\|WP_011723452.1\|280304_280772_+\|excisionase-family-DNA-binding-protein	unknown	unknown	gnl\|CDD\|200128

Protein	Function_ID	Function_description	E-value
NC_008595.1\|WP_033722258.1\|273382_275530_-\|site-specific-DNA-methyltransferase	gnl\|CDD\|334588	pfam01555, N6_N4_Mtase, DNA methylase. Members of this family are DNA methylases. The family contains both N-4 cytosine-specific DNA methylases and N-6 Adenine-specific DNA methylases.	1.9073e-08
NC_008595.1\|WP_011723458.1\|286608_286875_+\|glutaredoxin-family-protein	gnl\|CDD\|239274	cd02976, NrdH, NrdH-redoxin (NrdH) family; NrdH is a small monomeric protein with a conserved redox active CXXC motif within a TRX fold, characterized by a glutaredoxin (GRX)-like sequence and TRX-like activity profile. In vitro, it displays protein disulfide reductase activity that is dependent on TRX reductase, not glutathione (GSH). It is part of the NrdHIEF operon, where NrdEF codes for class Ib ribonucleotide reductase (RNR-Ib), an efficient enzyme at low oxygen levels. Under these conditions when GSH is mostly conjugated to spermidine, NrdH can still function and act as a hydrogen donor for RNR-Ib. It has been suggested that the NrdHEF system may be the oldest RNR reducing system, capable of functioning in a microaerophilic environment, where GSH was not yet available. NrdH from Corynebacterium ammoniagenes can form domain-swapped dimers, although it is unknown if this happens in vivo. Domain-swapped dimerization, which results in the blocking of the TRX reductase binding site, could be a mechanism for regulating the oxidation state of the protein.	3.2867e-16
NC_008595.1\|WP_011723454.1\|281198_283997_+\|bifunctional-DNA-primase/polymerase	gnl\|CDD\|240129	cd04859, Prim_Pol, Prim_Pol: Primase-polymerase (primpol) domain of the type found in bifunctional replicases from archaeal plasmids, including ORF904 protein of the crenarchaeal plasmid pRN1 from Sulfolobus islandicus (pRN1 primpol). These primpol domains belong to the archaeal/eukaryal primase (AEP) superfamily. This group includes archaeal plasmids and bacteriophage AEPs. The ORF904 protein is a multifunctional protein having ATPase, primase and DNA polymerase activity, and may play a role in the replication of the archaeal plasmid. The pRN1 primpol domain exhibits DNA polymerase and primase activities; a cluster of active site residues (three acidic residues, and a histidine) is required for both these activities. For pRN1 primpol, the primase activity prefers dNTPs to rNTPs; incorporation of dNTPs requires rNTP as cofactor. The pRN1 primpol contains an unusual zinc-binding stem, which is not conserved in other members of this group.	2.17641e-23
NC_008595.1\|WP_011723444.1\|270791_273383_-\|hypothetical-protein	gnl\|CDD\|368155	pfam04851, ResIII, Type III restriction enzyme, res subunit.	7.57682e-05
NC_008595.1\|WP_011723459.1\|286871_287255_+\|helix-turn-helix-domain-containing-protein	gnl\|CDD\|378935	pfam12728, HTH_17, Helix-turn-helix domain. This domain is a DNA-binding helix-turn-helix domain.	0.00853607
NC_008595.1\|WP_011723442.1\|270076_270274_-\|helix-turn-helix-domain-containing-protein	gnl\|CDD\|378935	pfam12728, HTH_17, Helix-turn-helix domain. This domain is a DNA-binding helix-turn-helix domain.	2.10475e-07
NC_008595.1\|WP_011723460.1\|287282_289778_+\|hypothetical-protein	gnl\|CDD\|223021	PHA03247, PHA03247, large tegument protein UL36; Provisional.	2.15861e-06
NC_008595.1\|WP_011723462.1\|290358_291492_+\|site-specific-integrase	gnl\|CDD\|271180	cd00799, INT_Cre_C, C-terminal catalytic domain of Cre recombinase (also called integrase). Cre-like recombinases are tyrosine based site specific recombinases. They belong to the superfamily of DNA breaking-rejoining enzymes, which share the same fold in their catalytic domain and the overall reaction mechanism. The bacteriophage P1 Cre recombinase maintains the circular phage replicon in a monomeric state by catalyzing a site-specific recombination between two loxP sites. The catalytic core domain of Cre recombinase is linked to a more divergent helical N-terminal domain, which interacts primarily with the DNA major groove proximal to the crossover region.	1.4076e-47
NC_008595.1\|WP_011723457.1\|285973_286585_+\|hypothetical-protein	gnl\|CDD\|340813	cd16962, RuvC, Crossover junction endodeoxyribonuclease RuvC. Crossover junction endodeoxyribonuclease RuvC is also called Holliday junction resolvase RuvC. It is part of the RuvABC pathway in Escherichia coli and other Gram-negative bacteria that is involved in processing Holliday junctions, which are formed by the reciprocal exchange of strands between two DNA duplexes. Holliday junction resolvases (HJRs) are endonucleases that specifically resolve Holliday junction DNA intermediates during homologous recombination. RuvC is thought to bind either on the open, DNA exposed face of a single RuvA tetramer, or to replace one of the two tetramers. Binding is proposed to be mediated by an unstructured loop on RuvC, which becomes structured on binding RuvA. RuvC can be bound to the complex in either orientation, therefore resolving Holliday junctions in either a horizontal or vertical manner. HJRs occur in archaea, bacteria, and in the mitochondria of certain fungi. These are referred to as the RuvC family of Holliday junction resolvases, RuvC being the Escherichia coli HJR. RuvC and its orthologs are homodimers and display structural similarity to RNase H and Hsp70.	2.39883e-06
NC_008595.1\|WP_085989534.1\|269780_270074_+\|helix-turn-helix-transcriptional-regulator	gnl\|CDD\|238045	cd00093, HTH_XRE, Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators.	2.09596e-09
NC_008595.1\|WP_011723448.1\|276508_277969_-\|hypothetical-protein	gnl\|CDD\|236090	PRK07764, PRK07764, DNA polymerase III subunits gamma and tau; Validated.	0.000212717
NC_008595.1\|WP_011723452.1\|280304_280772_+\|excisionase-family-DNA-binding-protein	gnl\|CDD\|200128	TIGR01764, Probable_excisionase, DNA binding domain, excisionase family. An excisionase, or Xis protein, is a small protein that binds and promotes excisive recombination; it is not enzymatically active. This model represents a number of putative excisionases and related proteins from temperate phage, plasmids, and transposons, as well as DNA binding domains of other proteins, such as a DNA modification methylase. This model identifies mostly small proteins and N-terminal regions of large proteins, but some proteins appear to have two copies. This domain appears similar, in both sequence and predicted secondary structure (PSIPRED) to the MerR family of transcriptional regulators (pfam00376). [Unknown function, General].	4.18324e-10

>NC_008595.1|WP_011723451.1|278975_279179_-|hypothetical-protein
MSTSYRPLITNLDRSIHDDVSGARTRLREAIKLLEQAPSTVADAEKLTAVVADLRAVERRLVELADR
>NC_008595.1|WP_155267846.1|278016_278979_-|hypothetical-protein
MNPARAQGIRMGDVTRASAGCSASSAKIERMSTKTRLGAAAAGIAAAVVLSACSTGVAGQPVAVQSSATTISTTAAQQPLRWVDVEAEAPQLDHDSVGARFGSAVYPGIGLTQVGPDKSTVDCSAGPAVTGGVVVAAHCDAAPGGRVQIYPNAKGSSPIPVGVITDRVLQQVDPVRDFALLRSTTVASGSTVIAGRWAIAGVLTEEAAPSALPVGSPVCVNAAYTGIRCGAVLSTDDDGELLFNVRTEIGDSGAAVFAVNADTGAATLIGIVRGGDEMTSTATYLAPALDKLGVSALVDPTASANTVADSRYSRMTTPAP
>NC_008595.1|WP_011723448.1|276508_277969_-|hypothetical-protein
MAPSGEHRPENLGQAAVHAAAVATGNSATTLRQQVKNLNAHASGKTITEQCELLTKQAGIAEKVSADLGIVAAALKIREDAARAWNRDAPKDSEIAAAKKAVADAKKALMDASAASGDTSAASPKLEAAQKKLGELIRRRRDADKAYDAAEKRADAKLKEISGQYAPHGGGRGHTADGTPETPAPSPGSPSPGAGSPSPGTGKPSAGAPGKTASGTAKPSATPAATPSSTKPTETETKSGDDLSGLLTQLASQQQQQPQSAQQAQPTAQATPAAATPQQQPEKDKDTAQGKASPLDRILGADGILDTGDLATLGVGAPLTLGGGSSHATPAAAVTPSAPASAAPSSTGLSASATANAQPVTSGTSAQGLHTSTDVTGRSGEPRSAFSVGPETKTSGASGATGTSAAPAHAAGTRPMGAGGMPMMPMGGMGGPAGGAGSSKDKESTTLASGSAESDLLHGRHTAAEAVPGGTIAQKDHPRRRGEDAA
>NC_008595.1|WP_011723447.1|276154_276499_+|hypothetical-protein
MAGKGELVPRPPKKVEYEIRFATTNAKKGWQDLAATIRNPLADAWDFLTRTPLANTPTNYPLKGQLGTITRGGERYERWQHKPTKQGDARIWFYVEGRTVYLEQVHTSHPNETK
>NC_008595.1|WP_011723446.1|275690_276152_+|prevent-host-death-protein
MTTIAFRTTTTRRSSDLSKHSAEVFAEAEDHPVTVTRRDGAPLVLMSQREAEGRARLLEFAAQLIGVAVDDDGPLAGRMSKAFPWMLALSPEDRATCAQDLVDAARASFSTDQPHLALSELTSWRETATAIAAGLGQADLDWLDDGDTVVERP
>NC_008595.1|WP_033722258.1|273382_275530_-|site-specific-DNA-methyltransferase
MSRLSDLIRQAKAADSQLGADLEREFRALTKRRSFGLVFERHQPEAVELAGRPVRKGDKVHILPPRGSRSRGDQRLWAVTGFEGRGENRSAKLVEAAQVEEPESTTAPVADLVVVAEFRDHIYPGLIETGRVERGGDKPFHTVINAENFHALEMLTYTHRHAIDAIYIDPPYNSGAKDWKYNNDYVESDDDYRHSKWLAMMERRLLIARELLNPADSVLIVTIDEKEYLRLGLLVEQMFPEARIQMVSSVINPGGASRTAAFTRVDEYIFFVKIGSAAPAKHSNDMLFTDVSEPDENRSPIWRGMLRGGSGPLRSDSPSKFYPVLVDRTTGAVVGAGEALPLGVDRATYTPPDGLDAVWPLKRGGVEGRWELNAATFEFRRSQGYVRAGDPNRRTGVRTIYYLRNAEIERLESGELISRGMNDRGFLDVDYNPERERTLPAKTVWNRQSHNATEYGSNLLKAILPNRKFPYPKSLYAVEDTLRFFIDDKPDAVVLDFFSGSGTTAHAVMRLNKQDGGRRQCISVTNNEVSADEQTRLRREGLRPGDADWEALGICDYITKPRITAAITGKTPEGAAISGEYKFNDEFPMSEGFEENAAFFTLTYEGPLSVAHHRAFARIAPMLWLRAGARGPIITEIGDKGWDLTDVYGVLDDLDTAARFVTEVKKTPSVATVYIVTDDDLAFQMVCRELPKGVRPIQLYESYLRNFEINSGRFA
>NC_008595.1|WP_011723444.1|270791_273383_-|hypothetical-protein
MEYTLKDYQVGAVAGVLDNLTQARTLYKQFGSKSRFALSAVTGAGKTVMAAAVIEALFFGSDEFDFAADPGAVVLWFSDDPSLNEQSRRRIQAAGGEQLDSRLRIIESTFNEPKLRPGNVYFLNAQKLSKGARLVRGDRNGDTDEMALVPRPDEVQSNIYDVIAETIADERLTLYFVQDEAHRGWNNSAGDRTTIVQRLVNGHGTTPPMPIVWGISATTQNFEDAFKDAPHGRVALPAVEVDSALVQASGLLKDDIVLSIPSESGTFDTVLLKRAVRKVIASTKAWAQYAKEQGETDPVVPLLVVQVRDGDTAATQTAVARAVEAVFEEWTDLPTQSFANVFGEHQDLSVNQVPVPYVAPETVQEETWIRVLFAKTAISTGWDCPRAEVLVSFRPAVDPTHITQLLGRMVRTPLARRIPGNQVLNSVECLLPFFDRKTATAVAEELMRGATGGGDGDSGGGPGRRVLFDPVTLLPNPEVPEEVWERFDMLPAQTIPKRAAKPIKRLTAIAKALSDDDLITDAGKQAHAHLHAVLDGRRVQYKDKIDAAVKDVMTMEGEELRGKLHSNTAISRKAFTDTADHRAIQDAYRAAGRVFSADLARTYVGHLAGDDADDDELRDATVQLAAAALVPEVAEAIDDEANKLAADWLQQTRVQRKGLTDERQAVYDELESMTTQPQPILLTRPRTGQADTKVRDAAGNESDLPTHKHHLLCDENGDVPANLNDWETLVLKQEMNAAGFVAWWRNPSRTAKDSLSIAYRDMSSGAFKALRPDFLFFSRRADGTIAANIVDPHGHHMSDAMPKLRGLADFAETFGAEYGRIEAVAKVGDTLRVLDLTKESVRKAVRDGADAKALYESDAAVDY
>NC_008595.1|WP_011723443.1|270361_270778_-|hypothetical-protein
MARRADSDEHYVLDLCDELLGVPGIRQARFDWLRGDPSPTRPRGVTLPVDGYWPDLRLVVEFQEEQHSQPSPFFDRRQTVSGMGRGEQRRRYDERKRTLIPEHGLRLVVIEKSVFTLKSRRIDRDRTRDLEVVRRHLA
>NC_008595.1|WP_011723442.1|270076_270274_-|helix-turn-helix-domain-containing-protein
MEPADDRLLTIPEAIQALRISRTHFFRLKRRGEIVGMRLGHRILIPAREITRLINENYHPPSSGG
>NC_008595.1|WP_085989534.1|269780_270074_+|helix-turn-helix-transcriptional-regulator
MFGVGDDDQQWVPKRVSAADAAAGAVLRRVRERAGLTLDQAAEASRISKAVLSRTERGERPARVTELLPLAAAYDMTAAELAAAIAADPAVQAAAMQ
>NC_008595.1|WP_011723452.1|280304_280772_+|excisionase-family-DNA-binding-protein
MTTTTTTRIRIGTPAVAERLGVSDETIRQEIKRGNLPAIRVGRTYRVLESDVDEYIAAAEAEAYSARKRKVGVEVTSGESEAGAEVRISGPSGSGKSSLVRELRGLWGDAVTAHRYSDDGSEVLRLSTIDVEPSIADVAENDGLPPRFHLANLNA
>NC_008595.1|WP_033722259.1|280866_281202_+|hypothetical-protein
MMTHTHIAVNRATAPLPPPLWSEILGPFADRVPFPISCGCSMWRRRGVGPAVYYAAHEGYTCMDGRTDADLAAAPAEPVAVPRLMIASVLWWRHVDEVYAAIRATHAGVIA
>NC_008595.1|WP_011723454.1|281198_283997_+|bifunctional-DNA-primase/polymerase
MSDSNRAVLERIVALGGHLMPLKPGIKKALLANWQLAPAITVDEALAHLAAGGNVGVHLGFSGLIALDAENLPATQHLLGAGFQLTVAPAKSRIEGNPKHQGSHVWLRVPKGIDPMALSSGERTMQVRLPGGGLIDVLAGGRYAVAPPSQLAEAPGWAYSAYAGSPLDLAVPLEDVEVAEAPKWLFDPTLPCPEPLTALRGCLAPKARRDLAELDARSVALTTEIDQVPWGDWIAGDRRLSPTGQVDGCGCEVWHWTDAEHDKSATLHDDCEVGSGAHLWSGTMMAALRLGSHCSRLDLATALRGESRSKTAASVGIRLGGEQELTAIDADDLDESAEEAEQRGDLTAAAELRKAAAVMRSRQHAVAPKEGAVFVGADSVVGAPAAPAAPTLTVVQGGGGVQPAAGESDGTDEDTAIEADDIDAGIPPEKLEAWAEIKRRGFNPNDRAVYPLGFHSTPEILERVMDYSDLTRATFHAARRAHAVHPIALYLNDLVRFGMRLPTDLGPFPGQPLSTFVAAVGRSGTGKTQSSRMSASPHDWTQIGRVCRPGTTPAETGDTPPPGLPEVFISVGAEALNRTHRLGSGQVLVDLYGEIEPLYDEDTGKVIKGKSHFLPNEHLALHVHEDEMSALIARSGGPQSTTMQTLCAAWARADIGDASRNAGTKAALSGDLDPYNLFLTGGLQPARAWTFFLTASLGFIQRFIHAAVTDPYRAVGLPVLADPGAVPPPSLDVGTATAFTLCESIKAAQAEAEKDSGVDSLAGFTELDSHELMVRIRLACLVAAYHGTLTVDELCWEHSGWIMEYSRRSRAHAEVEKERAAADDAGDAEKLRTHGKRVAAADDESRVRSAANRILGKLAEAGDAGLTEGEARKWLSGVRRNGRPSERALYGADALRVVKASEGVTFDGIRMRSASRGQAPLTAAPTIGSLGA
>NC_008595.1|WP_011723455.1|284491_285316_-|hypothetical-protein
MTVEAAPWPSTFPSYVASWYRWSMDSDATDAGIRNELARVLAIVEVVTERPDHHAETSSDLAADEARFPDIWAATVARRGLVHAAENFEAACLLMLNGDWTAPQYALLRAAYESAGAATWLLQPGDIDTRLARLLWQHRESWRYSTKAYGGTPLDHDREERQRWADDAAARLGIDLRAGRSGGFENLIEEIDDLPGQPESPADRMAAVLRREPREDVGPERGDHGDRQRRDLRARTDQSANPEPGAVPHRPERGAASGAAGVGLVPHPHHDAAA
>NC_008595.1|WP_155267847.1|285513_285789_+|carnitine-racemase
MAETISSADAAVGSLVHALASNLDADALRTAVQQALLAAEIEHGDAFFLGELLPDVIAAEVWHGEAVLTAPEALRVGLGYVAAAIVAGATL
>NC_008595.1|WP_011723457.1|285973_286585_+|hypothetical-protein
MLNPSTAGRTVVGLDLSLTGAGIAAFDLVTGDLSTAVHRSQAPKSDTLGAHVARHRALVDGIVQQTIGCDPALVVVEGLRFSVSAQDSSLSRRGFLWWAVVEGLVNAGAPVLEVTPSQIKQLATGKGNASKNMIVAEYALRWPDATRDKNVEDRADAAFAAALGVAYLRAPVLPFKVTGTRRKALAKLPAPSIPPRIAAAEAA
>NC_008595.1|WP_011723458.1|286608_286875_+|glutaredoxin-family-protein
MTITLYTQPGCGGCIFAAKDLTKAGVPFTERNVRADPDAADMVHRLYQEHRDPGVVPETPVIVIDDEVFFGAVELHAYLRELGRESAA
>NC_008595.1|WP_011723459.1|286871_287255_+|helix-turn-helix-domain-containing-protein
MSGAIRRPAPGGGVFITRPAAAALRGVTRRRIDSLIQQGKLPAYEVAGRVMVLEADVLALELPTAPPDGWISRHAAAKVLGCTHRAVGLMVARGDLPAETFNGRLYVREADVRAAANPRRVIPPRRR
>NC_008595.1|WP_011723460.1|287282_289778_+|hypothetical-protein
MAQFGGLASPIPDPTPQPHGAASTTDIPVRGTPDAADTKPEPATESKPDAEEKRRPNRDGKTPADPKPVPDAGEKPDTDEKPKPDVDKAEPKAKVKDIGQVTANDKVSTIGKSFGKAYLEAAKSPIKGIPAIVKAEYKAGTALGEKLAGKIAGEGLLKSASRVSLKTAGRLVPGVGTAIGVISAYKNFEQGDYVGAAINMVSAIPGPIGWVGIAASTAWEAFDLGGNKIGQWDSPDGSTTHILPAAAHDIGGVTALDSQLREAQQCVFSFQDGPRGKVWDSNPPEALRLDGADIQKEIAEALGGISDLFAEVDRVMSSAGEAYFDEYKARLQPHLEAMAALKEQVKPFTQQLGNASDGAATAYTAVLDANRAAREQLVADGKLSDQGPASTFTSAVSAAGSQVTAADQNIANLFGEPAAVLTATVASGTGTRIDPSKKGAPVQTTASPAAQTPVTPTSQTPTVTPKTETPAKTTDALGDLLRSLNQKQQMPTTPSTPNLGNGLGSGSPLGTGGSPLSTSPSKPLDTSSDRKLDDGRKGEEKKEERKLAEPKKEKSETKPSLAASKTDNAKAPESKLATAEKPGAHTAAVPAQPSAAAAAANPAAPAAQGQSAPPEQSKQVDVKGTRVEFPDAKTAKLASLLANADPAHPLSLAEAAKMAGLTPPVPGQDPGSQVAPAQAKPGDLLVAGDKKYMLLEPGKFYDLQEYKVVSADQLPQDAGSRGGYFHLNDPSPTGAPGTQPVSGQTPGGVDQAVPGGTPPPAAPADATPQKPHDPAAGAPAPSGGVPSAGTPGAPKPTATGGGPSSAEATQTGVGQPSPSPSTSALDPTAVR
>NC_008595.1|WP_011723462.1|290358_291492_+|site-specific-integrase
MILPAVTAGAELPDLPVDVVERIRIATIDSQSEGTRRAYSSAWRRFEGWCRRNGYESLPAHPTVIAAYLVDAAETVTENGERAYSTVSLGKWCAAIFDRHRRAGVEPNPAAHELVRQTASGIRRQYAARGDRPRQPRTPLLTDDVMLLVSTAREQATGWASQVCERRDSALLLMGFAGAFRRSELSGLTGGDVELHAADGIHVHLRKSKTDQLGEGGTYPLPRTKDALRCPACAYVRWAAVVSAHEDGGNGAVIRLLTDSPEFGSRHTCRSRAPKIDRRAPLFRSCRNGVLSEGPLSGAGIHAVIRRRALRAGFDREAVERLGGHSLRAGFVTQAARAGADHHAIMRQTGHRTPAMVTRYVRESAPLIGNAVTVLGL

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Crispr_ID: NC_008595_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_008595_2

1474589-1474664

Orphan

Consensus_repeat	Method
GCAGGAGGAGCGGCGCTGATGTCT	CRISPRCasFinder

1 spacers

The CRISPR arrays of NC_008595_2

>merge|NC_008595|2|1474589-1474664|CRISPRCasFinder
GCAGGAGGAGCGGCGCTGATGTCTCGCGTCGCGACGATGCAGAGCGCAGCGATGAGGAGGAGCGGCGCTGATGTCT

>NC_008595|2|2|1474589-1474664|CRISPRCasFinder
GCAGGAGGAGCGGCGCTGATGTCT	CGCGTCGCGACGATGCAGAGCGCAGCGA
TGAGGAGGAGCGGCGCTGATGTCT

Protein	Signature genes	Signature genes Name	Protein_function
NC_008595.1\|WP_003877295.1\|1480308_1481973_+\|F0F1-ATP-synthase-subunit-alpha	unknown	unknown	gnl\|CDD\|236448
NC_008595.1\|WP_023882656.1\|1460661_1461189_+\|hypothetical-protein	unknown	unknown	unknown
NC_008595.1\|WP_011724194.1\|1461521_1463054_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|227697
NC_008595.1\|WP_024636915.1\|1478101_1478350_+\|F0F1-ATP-synthase-subunit-C	unknown	unknown	gnl\|CDD\|180303
NC_008595.1\|WP_003873232.1\|1472285_1472528_+\|50S-ribosomal-protein-L31	unknown	unknown	gnl\|CDD\|234576
NC_008595.1\|WP_011724196.1\|1465259_1466678_+\|diaminopimelate-decarboxylase	unknown	unknown	gnl\|CDD\|273415
NC_008595.1\|WP_011724205.1\|1482922_1484380_+\|F0F1-ATP-synthase-subunit-beta	unknown	unknown	gnl\|CDD\|236447
NC_008595.1\|WP_023861298.1\|1469115_1470063_+\|homoserine-kinase	unknown	unknown	gnl\|CDD\|234920
NC_008595.1\|WP_024636927.1\|1463050_1463365_+\|hypothetical-protein	unknown	unknown	unknown
NC_008595.1\|WP_011724197.1\|1468003_1469086_+\|threonine-synthase	unknown	unknown	gnl\|CDD\|236013
NC_008595.1\|WP_011724202.1\|1476783_1477266_+\|ATP-synthase-subunit-I	unknown	unknown	gnl\|CDD\|377159
NC_008595.1\|WP_003873221.1\|1481979_1482894_+\|F0F1-ATP-synthase-subunit-gamma	unknown	unknown	gnl\|CDD\|235535
NC_008595.1\|WP_003873236.1\|1466681_1468007_+\|homoserine-dehydrogenase	unknown	unknown	gnl\|CDD\|235783
NC_008595.1\|WP_003873226.1\|1477258_1478017_+\|F0F1-ATP-synthase-subunit-A	unknown	unknown	gnl\|CDD\|235617
NC_008595.1\|WP_011724204.1\|1478900_1480241_+\|F0F1-ATP-synthase-subunit-B/delta	unknown	unknown	gnl\|CDD\|184048
NC_008595.1\|WP_003873224.1\|1478359_1478893_+\|F0F1-ATP-synthase-subunit-B	unknown	unknown	gnl\|CDD\|180240
NC_008595.1\|WP_011724201.1\|1472624_1473698_+\|peptide-chain-release-factor-1	unknown	unknown	gnl\|CDD\|234801
NC_008595.1\|WP_003873219.1\|1484419_1484785_+\|F0F1-ATP-synthase-subunit-epsilon	unknown	unknown	gnl\|CDD\|234796
NC_008595.1\|WP_029248424.1\|1470330_1472184_+\|transcription-termination-factor-Rho	unknown	unknown	gnl\|CDD\|237171
NC_008595.1\|WP_003873228.1\|1475344_1476568_+\|undecaprenyl/decaprenyl-phosphate-alpha-N-acetylglucosaminyl-1-phosphate-transferase	unknown	unknown	gnl\|CDD\|133463

Protein	Function_ID	Function_description	E-value
NC_008595.1\|WP_003877295.1\|1480308_1481973_+\|F0F1-ATP-synthase-subunit-alpha	gnl\|CDD\|236448	PRK09281, PRK09281, F0F1 ATP synthase subunit alpha; Validated.	0
NC_008595.1\|WP_011724194.1\|1461521_1463054_+\|hypothetical-protein	gnl\|CDD\|227697	COG5410, COG5410, Uncharacterized protein conserved in bacteria [Function unknown].	6.79726e-40
NC_008595.1\|WP_024636915.1\|1478101_1478350_+\|F0F1-ATP-synthase-subunit-C	gnl\|CDD\|180303	PRK05880, PRK05880, F0F1 ATP synthase subunit C; Validated.	2.15516e-33
NC_008595.1\|WP_003873232.1\|1472285_1472528_+\|50S-ribosomal-protein-L31	gnl\|CDD\|234576	PRK00019, rpmE, 50S ribosomal protein L31; Reviewed.	3.16914e-41
NC_008595.1\|WP_011724205.1\|1482922_1484380_+\|F0F1-ATP-synthase-subunit-beta	gnl\|CDD\|236447	PRK09280, PRK09280, F0F1 ATP synthase subunit beta; Validated.	0
NC_008595.1\|WP_023861298.1\|1469115_1470063_+\|homoserine-kinase	gnl\|CDD\|234920	PRK01212, PRK01212, homoserine kinase; Provisional.	5.4215e-98
NC_008595.1\|WP_011724196.1\|1465259_1466678_+\|diaminopimelate-decarboxylase	gnl\|CDD\|273415	TIGR01048, Diaminopimelate_decarboxylase, diaminopimelate decarboxylase. This family consists of diaminopimelate decarboxylase, an enzyme which catalyzes the conversion of diaminopimelic acid into lysine during the last step of lysine biosynthesis. [Amino acid biosynthesis, Aspartate family].	6.54868e-178
NC_008595.1\|WP_011724197.1\|1468003_1469086_+\|threonine-synthase	gnl\|CDD\|236013	PRK07409, PRK07409, threonine synthase; Validated.	0
NC_008595.1\|WP_011724202.1\|1476783_1477266_+\|ATP-synthase-subunit-I	gnl\|CDD\|377159	pfam03899, ATP-synt_I, ATP synthase I chain. The atp operon of alkaliphilic Bacillus pseudofirmus OF4, as in most prokaryotes, contains the eight structural genes for the F-ATPase (ATP synthase), which are preceded by an atpI gene that encodes a membrane protein with 2 TMSs. A tenth gene, atpZ, has been found in this operon, which is upstream of and overlapping with atpI. AtpI is a Ca2+/Mg2+ transporter.	3.30191e-06
NC_008595.1\|WP_003873221.1\|1481979_1482894_+\|F0F1-ATP-synthase-subunit-gamma	gnl\|CDD\|235535	PRK05621, PRK05621, F0F1 ATP synthase subunit gamma; Validated.	2.30959e-141
NC_008595.1\|WP_003873236.1\|1466681_1468007_+\|homoserine-dehydrogenase	gnl\|CDD\|235783	PRK06349, PRK06349, homoserine dehydrogenase; Provisional.	0
NC_008595.1\|WP_003873226.1\|1477258_1478017_+\|F0F1-ATP-synthase-subunit-A	gnl\|CDD\|235617	PRK05815, PRK05815, F0F1 ATP synthase subunit A; Validated.	3.09617e-62
NC_008595.1\|WP_011724204.1\|1478900_1480241_+\|F0F1-ATP-synthase-subunit-B/delta	gnl\|CDD\|184048	PRK13428, PRK13428, F0F1 ATP synthase subunit delta; Provisional.	0
NC_008595.1\|WP_003873224.1\|1478359_1478893_+\|F0F1-ATP-synthase-subunit-B	gnl\|CDD\|180240	PRK05759, PRK05759, F0F1 ATP synthase subunit B; Validated.	3.14907e-45
NC_008595.1\|WP_011724201.1\|1472624_1473698_+\|peptide-chain-release-factor-1	gnl\|CDD\|234801	PRK00591, prfA, peptide chain release factor 1; Validated.	0
NC_008595.1\|WP_003873219.1\|1484419_1484785_+\|F0F1-ATP-synthase-subunit-epsilon	gnl\|CDD\|234796	PRK00571, atpC, F0F1 ATP synthase subunit epsilon; Validated.	1.19782e-38
NC_008595.1\|WP_029248424.1\|1470330_1472184_+\|transcription-termination-factor-Rho	gnl\|CDD\|237171	PRK12678, PRK12678, transcription termination factor Rho; Provisional.	0
NC_008595.1\|WP_003873228.1\|1475344_1476568_+\|undecaprenyl/decaprenyl-phosphate-alpha-N-acetylglucosaminyl-1-phosphate-transferase	gnl\|CDD\|133463	cd06853, GT_WecA_like, This subfamily contains Escherichia coli WecA, Bacillus subtilis TagO and related proteins. WecA is an UDP-N-acetylglucosamine (GlcNAc):undecaprenyl-phosphate (Und-P) GlcNAc-1-phosphate transferase that catalyzes the formation of a phosphodiester bond between a membrane-associated undecaprenyl-phosphate molecule and N-acetylglucosamine 1-phosphate, which is usually donated by a soluble UDP-N-acetylglucosamine precursor. WecA participates in the biosynthesis of O antigen LPS in many enteric bacteria and is also involved in the biosynthesis of enterobacterial common antigen. A conserved short sequence motif and a conserved arginine at a cytosolic loop of this integral membrane protein were shown to be critical in recognition of substrate UDP-N-acetylglucosamine.	7.47756e-78

>NC_008595.1|WP_011724201.1|1472624_1473698_+|peptide-chain-release-factor-1
MTQPVQTIDVLLAEHADLERRLSDPDLHSNPDEARKAGRRFARLAPIVGTYRKLMAAREDLETARELAADDDSFTAEVADLESRVAQLDTQLTDMLAPRDSHDADDIVLEVKSGEGGEESALFAADLARMYIRYAERHGWTVTVLDEITSDLGGYKDATLSIRSKGDSADGVWSRMKFEGGVHRVQRVPVTESQGRVHTSAAGVLVYPEPEEVAEVQIDESDLRIDVFRSSGKGGQGVNTTDSAVRITHLPTGVVVTCQNERSQLQNKARALQVLAARLQAMAEEQASAEASADRASQIRTVDRSERIRTYNFPENRITDHRIGFKAHNLDQVLDGDLDALFDALAAADKQSRLQQA
>NC_008595.1|WP_003873232.1|1472285_1472528_+|50S-ribosomal-protein-L31
MKADIHPTYAETTVLCGCGNTFQTRSTKDGGRIVVEVCSQCHPFYTGKQKILDSGGRVARFEKRYGKRKAGAEKAESADK
>NC_008595.1|WP_029248424.1|1470330_1472184_+|transcription-termination-factor-Rho
MTDTDLFTAGENTDANQLSPAVTTDTPDAKTHAPVGALTTMVLPELRALANQVGVKGTSGMRKNELIAAIKEVRGQANGAAPAEQANGAEPAEDSGKPDAKDAKDDTTPDTKDANDHTGAQSAAEAPAQNGATAEAPRRERRSASRDAGAAGRGNDDADRETDGREQNKQDSREQSKQDGGDQDQQSSGGQQGRGSNQQDDDGEGRQGRRGRRFRDRRRRGERSGEGGDAELREDDVVQPVAGILDVLDNYAFVRTSGYLAGPHDVYVSMNMVRKNGLRRGDAVTGAVRVPKDGEQPNQRQKFNPLVRLDSVNGGSVEDAKKRPEFGKLTPLYPNQRLRLETTPDRLTTRVIDLIMPIGKGQRALIVSPPKAGKTTILQDIANAITKNNPECHLMVVLVDERPEEVTDMQRSVKGEVIASTFDRPPSDHTSVAELAIERAKRLVEQGKDVVVLLDSITRLGRAYNNASPASGRILSGGVDSTALYPPKRFLGAARNIEEGGSLTIIATAMVETGSTGDTVIFEEFKGTGNAELKLDRKIAERRVFPAVDVNPSGTRKDELLLSPDEFGIVHKLRRVLSGLDSHQAIDLLMSQLRKTKNNYEFLVQVSKTTPGAMDND
>NC_008595.1|WP_023861298.1|1469115_1470063_+|homoserine-kinase
MVTSMLPAGLVASAVVSASSANLGPGFDSIGLALSLIDEITVETTDSGLVVQVEGEGADQVPLGPEHLVVRAVECGLRAVGVRAAGLVVRCRNAIPHSRGLGSSAAAVVGGLAAANGLVAQANCQPLSDAALIQLSSEFEGHPDNAAAAVFGGAIVSWIDRGGQHPRYAAAPLRLHPDIHLYCAIPQERSLTAETRVLLPAQVSHEDARFNVSRAALLVVALTERPDLLMAATEDVLHQPQRAPAMPASAEYLRLLRRHNVAATLSGAGPSLIALTTASALPPEVTEYGAANGFTLAEMTAGQGVRWSPGVTVVG
>NC_008595.1|WP_011724197.1|1468003_1469086_+|threonine-synthase
MSAQRTAVHQPWPGLIEAYRDRLPVGDDWTPVTLLEGGTPLIPARRLSEKTGCTVHLKVEGLNPTGSFKDRGMTMAVTDALARGQQAVLCASTGNTSASAAAYAARAGITCAVLIPQGKIAMGKLAQAVMHGAKIIQIDGNFDDCLELARKMAADFPTISLVNSVNPVRIEGQKTAAFEIVDVLGAAPDVHALPVGNAGNITAYWKGYTEYHHEGLIEKLPRMLGTQAAGAAPLVHGEPVKNPETIATAIRIGAPASWTAAVDAQQQSHGRFLAATDDEILAAYHLVAESEGVFVEPASAASIAGLLKAVEDGWVARGSTVVCTVTGNGLKDPDTALRDMPTVTPLPVDPVLVVEKLGLA
>NC_008595.1|WP_003873236.1|1466681_1468007_+|homoserine-dehydrogenase
MPRDEKPVGVAVLGLGNVGSEVVRIIEDSAGDLAARIGAPLVLRGVGVRRVADDRGVPVELLTDDIEGLAARDDVDIVVELMGPVEPSRKAILCALEHGKSVVTANKALLSTSTGELAQAAESAHVDLYFEAAVAGAIPVIRPLTQSLAGDTVLRVAGIVNGTTNYILSAMDSTGADYDTALAEASDLGYAEADPTADVEGYDAAAKAAILASIAFHTRVTADDVYREGITKITPADFASARALGCTIKLLSICERITGDDGQERVSARVYPALVPLSHPLATVNGAFNAVVVEARASGRLMFYGQGAGGAPTASAVAGDLVMAARNRVLGSRGPRESKYAQLPVAPMGFISTRYYVSMNVADKPGVLSSVAAEFAKREVSIAEVRQEGVADEGGRRVGARIVVVTHTATDAALSETVHALADLDVVQSVTSVLRLEGTSL
>NC_008595.1|WP_011724196.1|1465259_1466678_+|diaminopimelate-decarboxylase
MNVHPAGPRHAEETRHPESPPRPQSPEELLLLAPNVWPRNATRNEAGVATIAGVAVTELAREYGTPLFVVDEDDFRSRCREIASAFGGGNNVHYAAKAFLCSEVARWIDEEGLSLDVCTGGELAVALHADFPPERITFHGNNKSVAELTAAVKAGVGHVVLDSMTEIERLDAIAADAGIVQDVFVRLTVGVEAHTHEFISTAHEDQKFGLSVASGSALAAVGRVFDTEHLRLVGLHSHIGSQIFDVAGFELAARRVIGLLHDAVEQFGVEKTAQIATVDLGGGLGISYLAADDPPPMGELAGKLSAIVQHESAAVGLPTPRLVVEPGRAIAGPGTITLYEVGTVKDVDVSATAHRRYVSVDGGMSDNIRTALYDAQYDARLVSRVSDAPAELARIVGKHCESGDIVVRDTWVPGDLRPGDLIGVAATGAYCYSLSSRYNMVCRPAVVAVRDGRARLVLRRETVDDLLSLEVR
>NC_008595.1|WP_024636927.1|1463050_1463365_+|hypothetical-protein
MTGCTAVLRTVGTIGGGELARAGRAKLRADLTTPAEPAALGDCDCARCRPEPLTDIDAQRALRHVSNQDAVAYARGEVTVVSLRGCDGDDCDGWVPMFTEAAAR
>NC_008595.1|WP_011724194.1|1461521_1463054_+|hypothetical-protein
MTAMTDRPRTPIAAMTAARATASARARRRPDTPAELARRLIPGYVVTPAIKLLSDELVRAVETPDARLIVTMPPRTGKSVQTSQVFPVWLLSRDPDAEVIVKSYGDALAEEHSAAARRLIAENPAVVGIELAADKQAVGRWRVAGHRGGMLAGGILSSTTGFGASVLLVDDPVKGAQEADSDAYRKRLYAEMRASLMTRLMPGASAIIVLTRWHPDDLAGSLLAEPGSRWRCVNIPAISTAGVPDALGRERSGVAMTSAVGRTAEQFREIKTEVGSRAWAAMYLGTPSTPEGGLVKAAWIDTWRLPAAPPGTVKIVVGVDPADSGQGDETGIIAAALTADGVVALIADVSGRMTSDAWAVRAVQLAADVGASEIAVEAFAARATYTRLVTEVLARFRVDRPIRVTGWPPKGTDRGKGDAVARSTGLLAALEVGRCRVAGFLPDFEAQAVTWEAGQHQPDRVAAAVVAYDVLAHSIGQGMHVVTPMDTARRAREGKISPPPAWMTRRVGGR
>NC_008595.1|WP_023882656.1|1460661_1461189_+|hypothetical-protein
MPTVADLTARQRQHLEICVHEAGHSVAGVIFGAQLRTAVVSDSRVSGVEGVTSFSDSPHGRDEEITYAGPWAQARWRAGGRRPTQREMYALFDGGARSDCGVLTAAGGTHLGHAVQPVIERAWPAVIRVAKQLHRTGEVNQTDVCEALGITDGGGPGSSQLAGLRAGMRPVPPLT
>NC_008595.1|WP_003873228.1|1475344_1476568_+|undecaprenyl/decaprenyl-phosphate-alpha-N-acetylglucosaminyl-1-phosphate-transferase
MSSTVSLVSSDVTDLAGGLLALSDRGAGVPLRELALVGLTAAIITYFATGPVRVLATRLGAVAYPRERDVHVTPTPRMGGLAMFLGVVCAVFLASQLPALTRGFVYSSGMPAVLVAGAVIMGIGLIDDRWGLDALTKFAGQITAASVLVTMGVAWSVLYIPIGGVGTIVLDQASSILLTLALTVSVVNAMNFVDGLDGLAAGLGLITALAICMFSVGLLRDHGGDVLFYPPAVISVVLAGACLGFLPHNFHRAKIFMGDSGSMLIGLMLAAASTTAAGPVSQNAYGARDVFALLSPFLLVAAVIFVPMLDLLLAIVRRTRAGRSAFSPDKMHLHHRLLQIGHSHRRVVLLIYLWVGIVAFGAASTIFFRPRDTAAVMLGAIVVAGIATAIPLLRRGDDYEDEEYDRQ
>NC_008595.1|WP_011724202.1|1476783_1477266_+|ATP-synthase-subunit-I
MTTPAQDAPLVFPSVAFRPVRLFAISVAITAVAVLAAGLSGHLMVGVFFGIGLLLGLLNAVLVRRSVDSITAREHPLKRSMAVNSASRLAIITVVGLIIAYLFRPAGLGVLFGLALFQVLLVASTALPVWKKLRAGDWAPSADGAAAGADGTEGRNSTDA
>NC_008595.1|WP_003873226.1|1477258_1478017_+|F0F1-ATP-synthase-subunit-A
MPETTFLAESAIEVGEHNHATWLGMTVNTDTILSTGIAALIVLALAFFLRAKITSTGVPSGVQLFWEAITVQMRDQIESAVGMRIAPFVLPLAVTIFVFILISNWLSVLPLQYTDKSGHTTELLKSAAADINYVLALALFVFVCYHVAGIWRRGVVGHPLAVLKGHVAFLAPINVVEELAKPISLSLRLFGNIFAGGILVALIALFPPYIMWAPNAIWKAFDLFVGAIQAFIFSILTILYFSQAMEIEEHHD
>NC_008595.1|WP_024636915.1|1478101_1478350_+|F0F1-ATP-synthase-subunit-C
MDPQVAAAALIGGGLIMGGGAIGAGIGDGIAGNALVSGIARQPEAQGRLFTPFFITVGLVEAAYFINLAFMALFVFATPVGT
>NC_008595.1|WP_003873224.1|1478359_1478893_+|F0F1-ATP-synthase-subunit-B
MGDASLSVLASSQVVAEGGNNFLVPNGTFFFVLAIFLIVLAVIGTFVVPPVMKVLRERDAMVAKTAADNRKAAEQFEAAQADYEEAMTEARVQASSLRDNARAEGRKVVEDARAKAEQEVLSTLQLAARQLKRERDAVELDLRANVASMSATLASRILGVDVAPAAATTSATKTSGR
>NC_008595.1|WP_011724204.1|1478900_1480241_+|F0F1-ATP-synthase-subunit-B/delta
MSTFIGQLVGFAAIVFLVVRYVVPPVRRLMAARQEAVRQQLQDAAAAADRLTESTTAHSKAVEAAKAESKRVVDEAQADAKRITEQLAAQAGLEAERIKSQGSRQVDLLRTQLTRQLRLELGHEAVRQAGELVRNYVADPAQQSATVDRFLDDLDAMAPAAADVQYPLMTKMRSSSRVALVNLTERFTTVAKDLDNKALSALSSELVSVAQMLDREIVVTRYLTVPAEDAGPRVRLIERLLSGKVGDVTLEVLRAAVSERWSANSDLIDALEHLSRQALLEVAERENKVDEVEEQLFRFSRILDVQPRLAILLGDYAVPVEGRVGLLRKVLDSASITVNPIVAALLTQTVELLRGRPAEEAVQFLAEVAVARRGEVVAQVSAAADLSGAQRSRLTEVLSRIYGHPVSVQLQIDTELLGGLLIAVADEVIDGTLASRLAAAEAQLPD
>NC_008595.1|WP_003877295.1|1480308_1481973_+|F0F1-ATP-synthase-subunit-alpha
MAELTISADDIQSAIEEYVGSFTSDTSREEVGTVVDAGDGIAHVEGLPSVMTQELLEFPGGVLGVALNLDEHSVGAVILGDFEKIEEGQQVKRTGEVLSVPVGDAFLGRVVNPLGQPIDGQGDIETDIRRALEIQAPSVVQRQSVKEPLQTGIKAIDAMTPIGRGQRQLIIGDRKTGKTAVCVDTILNQRQNWESGDEKKQVRCVYVAIGQKGTTIASVRRALEEGGAMDYTTIVAAPASDSAGFKWLAPYTGSAIAQHWMYDGKHVLIVFDDLSKQAEAYRAISLLLRRPPGREAYPGDVFYLHSRLLERCAKLSDELGGGSMTGLPIIETKANDISAYIPTNVISITDGQCFLESDLFNQGVRPAINVGVSVSRVGGAAQIKAMKEVAGSLRLDLSQFRELEAFAAFASDLDATSKAQLDRGARLVELLKQPQYQPMPVEEQVVSIFLGTGGHLDSVPVEDVRRFETELLDHMRASEDKILAGIRDTQKLSDEAAEELEKVINNFKKGFAATGGASVVPDEHVEALDEEELEKESVKVKKPAPEKKAKKEQK
>NC_008595.1|WP_003873221.1|1481979_1482894_+|F0F1-ATP-synthase-subunit-gamma
MAATLRELRGRIRSAGSIKKITKAQELIATSRIGRAQARLDSARPYAFQITAMLTTLAAEAALDHPLLVERPEPKRAGVLVVSSDRGLCGAYNASIFRRAEELFSLLREQGKTPVLYSVGRKALNYYTFRNWDISGSWTGFSEQPQYENAAEIAETLVESFMRGTGGEDEGESDAESVDELHIVYTEFKSMLSQSAVAHRIAPMVVEYVEEPPEVRTLYSFEPDATTLFESLLPRYLTTRVYAALLESAASELASRQRAMKSATDNADDLIKALTLMANRERQAQITQEISEIVGGANALADAR
>NC_008595.1|WP_011724205.1|1482922_1484380_+|F0F1-ATP-synthase-subunit-beta
MPATETADKNTKSANSDTSGRVVRVTGPVVDVEFPRGSVPALFNALHAEITFEELAKTLTLEVAQHLGDNLVRTISLQPTDGLVRGVEVIDTGRSISVPVGQEVKGHVFNALGHCLDKPGYGEDFEHWSIHRKPPPFEELEPRTEMLETGLKVVDLLTPYVRGGKIALFGGAGVGKTVLIQEMINRIARNFGGTSVFAGVGERTREGNDLWVELQEANVLKDTALVFGQMDEPPGTRMRVALSALTMAEWFRDEAGQDVLLFIDNIFRFTQAGSEVSTLLGRMPSAVGYQPTLADEMGELQERITSTRGRSITSMQAVYVPADDYTDPAPATTFAHLDATTELSRSVFSKGIFPAVDPLASSSTILDPGVVGEEHYRVAQEVIRILQRYKDLQDIIAILGIDELSEEDKQLVNRARRIERFLSQNMMAAEQFTGQPGSTVPLKETIEAFDRLTKGEFDHVPEQAFFLIGGLDDLAKKAESLGAKL
>NC_008595.1|WP_003873219.1|1484419_1484785_+|F0F1-ATP-synthase-subunit-epsilon
MAELNVEIVAVDRKIWSGEATFLFTRTTVGEIGILPRHIPLVAQLVDDAMVRVEREGEDDLRIAVDGGFLSVTEETVTILAESAEFSSEIDESAAREAAESDDPRVAARGRARLRAVGAID

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Crispr_ID: NC_008595_3

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_008595_3

2322571-2322653

Orphan

Consensus_repeat	Method
AGGAGCCGGGCGATTCAGCTTGGGCC	CRISPRCasFinder

1 spacers

The CRISPR arrays of NC_008595_3

>merge|NC_008595|3|2322571-2322653|CRISPRCasFinder
AGGAGCCGGGCGATTCAGCTTGGGCCTGGCGACGATGCGGGCCGGGCCGGCCCGAGGAGGAGCCGGGCGATTCAGCTTGGGCC

>NC_008595|3|3|2322571-2322653|CRISPRCasFinder
AGGAGCCGGGCGATTCAGCTTGGGCC	TGGCGACGATGCGGGCCGGGCCGGCCCGAGG
AGGAGCCGGGCGATTCAGCTTGGGCC

Protein	Signature genes	Signature genes Name	Protein_function
NC_008595.1\|WP_011724718.1\|2314338_2314728_+\|hypothetical-protein	unknown	unknown	unknown
NC_008595.1\|WP_011724724.1\|2327666_2328269_-\|GNAT-family-N-acetyltransferase	unknown	unknown	gnl\|CDD\|223532
NC_008595.1\|WP_003872239.1\|2325969_2326863_+\|hypothetical-protein	unknown	unknown	unknown
NC_008595.1\|WP_011724725.1\|2328661_2329063_+\|DUF3040-domain-containing-protein	unknown	unknown	gnl\|CDD\|378610
NC_008595.1\|WP_003872238.1\|2326866_2327547_-\|DUF3153-domain-containing-protein	unknown	unknown	unknown
NC_008595.1\|WP_003872240.1\|2324654_2325704_-\|polyprenyl-synthetase-family-protein	unknown	unknown	gnl\|CDD\|223220
NC_008595.1\|WP_019685223.1\|2316918_2317803_+\|hypothetical-protein	unknown	unknown	unknown
NC_008595.1\|WP_011724728.1\|2331065_2332340_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|223021
NC_008595.1\|WP_003878126.1\|2322734_2323139_+\|DNA-binding-protein	unknown	unknown	gnl\|CDD\|375793
NC_008595.1\|WP_003872235.1\|2329499_2329931_+\|division/cell-wall-cluster-transcriptional-repressor-MraZ	unknown	unknown	gnl\|CDD\|224912
NC_008595.1\|WP_009976532.1\|2312631_2313069_+\|SRPBCC-family-protein	unknown	unknown	gnl\|CDD\|176861
NC_008595.1\|WP_009976539.1\|2317823_2318312_+\|polyadenylate-specific-3'-exoribonuclease-AS	unknown	unknown	gnl\|CDD\|374562
NC_008595.1\|WP_003872245.1\|2318403_2319792_+\|3-deoxy-7-phosphoheptulonate-synthase-class-II	unknown	unknown	gnl\|CDD\|366662
NC_008595.1\|WP_011724723.1\|2323132_2324650_-\|alpha-(1-6)-mannopyranosyltransferase-A	unknown	unknown	gnl\|CDD\|274589
NC_008595.1\|WP_011724721.1\|2319788_2321234_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|223727
NC_008595.1\|WP_085988250.1\|2313061_2314342_+\|ArsA-family-ATPase	unknown	unknown	gnl\|CDD\|223082
NC_008595.1\|WP_009976536.1\|2314815_2315541_+\|1-acyl-sn-glycerol-3-phosphate-acyltransferase	unknown	unknown	gnl\|CDD\|153251
NC_008595.1\|WP_009976542.1\|2321368_2322559_-\|serine/threonine-protein-kinase	unknown	unknown	gnl\|CDD\|270916
NC_008595.1\|WP_010949412.1\|2315537_2316827_-\|DUF2029-domain-containing-protein	unknown	unknown	gnl\|CDD\|172015
NC_008595.1\|WP_095785446.1\|2329905_2331066_+\|16S-rRNA-(cytosine(1402)-N(4))-methyltransferase-RsmH	unknown	unknown	gnl\|CDD\|223352

Protein	Function_ID	Function_description	E-value
NC_008595.1\|WP_011724725.1\|2328661_2329063_+\|DUF3040-domain-containing-protein	gnl\|CDD\|378610	pfam11239, DUF3040, Protein of unknown function (DUF3040). Some members in this family of proteins with unknown function are annotated as membrane proteins however this cannot be confirmed.	1.92225e-29
NC_008595.1\|WP_011724724.1\|2327666_2328269_-\|GNAT-family-N-acetyltransferase	gnl\|CDD\|223532	COG0456, RimI, Acetyltransferases [General function prediction only].	1.54953e-11
NC_008595.1\|WP_003872240.1\|2324654_2325704_-\|polyprenyl-synthetase-family-protein	gnl\|CDD\|223220	COG0142, IspA, Geranylgeranyl pyrophosphate synthase [Coenzyme metabolism].	7.8022e-68
NC_008595.1\|WP_011724728.1\|2331065_2332340_+\|hypothetical-protein	gnl\|CDD\|223021	PHA03247, PHA03247, large tegument protein UL36; Provisional.	2.33952e-09
NC_008595.1\|WP_003878126.1\|2322734_2323139_+\|DNA-binding-protein	gnl\|CDD\|375793	pfam18367, Rv2175c_C, Rv2175c C-terminal domain of unknown function. This is the C-terminal domain of unknown function found in actinomycetes such as M. tuberculosis Rv2175c. Rv2175c has a DNA binding activity and possesses a winged helix-turn-helix fold, furthermore it is identified as a substrate of the PknL kinase.	6.93858e-28
NC_008595.1\|WP_003872235.1\|2329499_2329931_+\|division/cell-wall-cluster-transcriptional-repressor-MraZ	gnl\|CDD\|224912	COG2001, COG2001, Uncharacterized protein conserved in bacteria [Function unknown].	6.88479e-66
NC_008595.1\|WP_009976532.1\|2312631_2313069_+\|SRPBCC-family-protein	gnl\|CDD\|176861	cd07819, SRPBCC_2, Ligand-binding SRPBCC domain of an uncharacterized subfamily of proteins. Uncharacterized group of the SRPBCC (START/RHO_alpha_C/PITP/Bet_v1/CoxG/CalC) domain superfamily. SRPBCC domains have a deep hydrophobic ligand-binding pocket and they bind diverse ligands. SRPBCC domains include the steroidogenic acute regulatory protein (StAR)-related lipid transfer (START) domains of mammalian STARD1-STARD15, the C-terminal catalytic domains of the alpha oxygenase subunit of Rieske-type non-heme iron aromatic ring-hydroxylating oxygenases (RHOs_alpha_C), Class I and II phosphatidylinositol transfer proteins (PITPs), Bet v 1 (the major pollen allergen of white birch, Betula verrucosa), CoxG, CalC, and related proteins. Other members of the superfamily include PYR/PYL/RCAR plant proteins, the aromatase/cyclase (ARO/CYC) domains of proteins such as Streptomyces glaucescens tetracenomycin, and the SRPBCC domains of Streptococcus mutans Smu.440 and related proteins.	3.92729e-51
NC_008595.1\|WP_009976539.1\|2317823_2318312_+\|polyadenylate-specific-3'-exoribonuclease-AS	gnl\|CDD\|374562	pfam16473, DUF5051, 3' exoribonuclease, RNase T-like. This is a highly divergent 3' exoribonuclease family. The proteins constitute a typical RNase fold, where the active site residues form a magnesium catalytic centre. The protein of the solved structure readily cleaves 3' overhangs in a time-dependent manner. It is similar to DEDD-type RNases and is an unusual ATP-binding protein that binds ATP and dATP. It forms a dimer in solution and both protomers in the asymmetric unit bind a magnesium ion through Asp-6 in UniProtKB:P9WJ73.	6.31788e-13
NC_008595.1\|WP_003872245.1\|2318403_2319792_+\|3-deoxy-7-phosphoheptulonate-synthase-class-II	gnl\|CDD\|366662	pfam01474, DAHP_synth_2, Class-II DAHP synthetase family. Members of this family are aldolase enzymes that catalyze the first step of the shikimate pathway.	0
NC_008595.1\|WP_011724723.1\|2323132_2324650_-\|alpha-(1-6)-mannopyranosyltransferase-A	gnl\|CDD\|274589	TIGR03459, crt_membr, carotene biosynthesis associated membrane protein. This model represents a family of hydrophobic and presumed membrane proteins found in the Actinobacteria. The genes encoding these proteins are syntenically associated with (found proximal to) genes of carotene biosynthesis ususally including phytoene synthase (crtB), phytoene dehydrogenase (crtI) and geranylgeranyl pyrophosphate synthase (ispA).	0
NC_008595.1\|WP_011724721.1\|2319788_2321234_-\|hypothetical-protein	gnl\|CDD\|223727	COG0654, UbiH, 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases [Coenzyme metabolism / Energy production and conversion].	5.66999e-14
NC_008595.1\|WP_085988250.1\|2313061_2314342_+\|ArsA-family-ATPase	gnl\|CDD\|223082	COG0003, ArsA, Predicted ATPase involved in chromosome partitioning [Cell division and chromosome partitioning].	1.30613e-81
NC_008595.1\|WP_009976536.1\|2314815_2315541_+\|1-acyl-sn-glycerol-3-phosphate-acyltransferase	gnl\|CDD\|153251	cd07989, LPLAT_AGPAT-like, Lysophospholipid Acyltransferases (LPLATs) of Glycerophospholipid Biosynthesis: AGPAT-like. Lysophospholipid acyltransferase (LPLAT) superfamily member: acyltransferases of de novo and remodeling pathways of glycerophospholipid biosynthesis which catalyze the incorporation of an acyl group from either acylCoAs or acyl-acyl carrier proteins (acylACPs) into acceptors such as glycerol 3-phosphate, dihydroxyacetone phosphate or lyso-phosphatidic acid. Included in this subgroup are such LPLATs as 1-acyl-sn-glycerol-3-phosphate acyltransferase (AGPAT, PlsC), Tafazzin (product of Barth syndrome gene), and similar proteins.	2.35417e-57
NC_008595.1\|WP_009976542.1\|2321368_2322559_-\|serine/threonine-protein-kinase	gnl\|CDD\|270916	cd14014, STKc_PknB_like, Catalytic domain of bacterial Serine/Threonine kinases, PknB and similar proteins. STKs catalyze the transfer of the gamma-phosphoryl group from ATP to serine/threonine residues on protein substrates. This subfamily includes many bacterial eukaryotic-type STKs including Staphylococcus aureus PknB (also called PrkC or Stk1), Bacillus subtilis PrkC, and Mycobacterium tuberculosis Pkn proteins (PknB, PknD, PknE, PknF, PknL, and PknH), among others. S. aureus PknB is the only eukaryotic-type STK present in this species, although many microorganisms encode for several such proteins. It is important for the survival and pathogenesis of S. aureus as it is involved in the regulation of purine and pyrimidine biosynthesis, cell wall metabolism, autolysis, virulence, and antibiotic resistance. M. tuberculosis PknB is essential for growth and it acts on diverse substrates including proteins involved in peptidoglycan synthesis, cell division, transcription, stress responses, and metabolic regulation. B. subtilis PrkC is located at the inner membrane of endospores and functions to trigger spore germination. Bacterial STKs in this subfamily show varied domain architectures. The well-characterized members such as S. aureus and M. tuberculosis PknB, and B. subtilis PrkC, contain an N-terminal cytosolic kinase domain, a transmembrane (TM) segment, and mutliple C-terminal extracellular PASTA domains. The PknB subfamily is part of a larger superfamily that includes the catalytic domains of other protein STKs, protein tyrosine kinases, RIO kinases, aminoglycoside phosphotransferase, choline kinase, and phosphoinositide 3-kinase.	2.12117e-115
NC_008595.1\|WP_010949412.1\|2315537_2316827_-\|DUF2029-domain-containing-protein	gnl\|CDD\|172015	PRK13375, pimE, mannosyltransferase; Provisional.	6.11261e-44
NC_008595.1\|WP_095785446.1\|2329905_2331066_+\|16S-rRNA-(cytosine(1402)-N(4))-methyltransferase-RsmH	gnl\|CDD\|223352	COG0275, COG0275, Predicted S-adenosylmethionine-dependent methyltransferase involved in cell envelope biogenesis [Cell envelope biogenesis, outer membrane].	3.50688e-153

>NC_008595.1|WP_009976542.1|2321368_2322559_-|serine/threonine-protein-kinase
MLDGRYLIESKIASGGTSTVYRGVDTRLDRPVAVKVMDPRYAGDEQFLTRFQREARAVARLKDPGLVAVYDQGLDARHPFLVMELIEGGTLRELLGERGPMPPYAVAAVLRPVLGGLAAAHRAGLVHRDVKPENVLISDDGEVKIADFGLVRAVAAAGITSASVILGTAAYLSPEQVRDGAATPRSDVYAAGILAYELLTGRTPFTGDSTLAIAYRRLDADVPPPSAAIDGVPAQFDDFVQRATARDPADRYADAVEMGADLDAIADELALPGFRVPAPRNSALHRSAALHREAGRRAPGAEPPARHPTRHLTRGPEEWPQPEPPAHVGAEPDDDEDDYEYQSVTGEFAGIPISEFVWARQHNRRMVLVWLALVLAVTGMVATAAWTIGRNLNGLF
>NC_008595.1|WP_011724721.1|2319788_2321234_-|hypothetical-protein
MGSTTQGVDSPNRLGEHAVVLGAGIAGLLAARVLSEFYDSVSVVERDKLPDYPCHRRGIPQGRHVHNFYSRGLQVLEELFPGLLDDLARAGAVVVDDGDLSRFYVRFGRYEMKNSGAFADPDALALHMTTRPFMEFHLRRRVKALPNVTFLDGHDVCDLLNTADIVNGVRITRRYNGFLMALDADLVVDAMGRSARTPAFLESLGYQRPTEERAVARYGYASQQLSMPEGSIAQRLVMFNPGGGRPAGLLLANEHDTFILAIGVPADTGEPPTDFAAMLAMAEPSLPPAIVEGLRRAYPIGEAVTYHHTAAFWRRYDQLADFPSGLLVMGDALCSLDPTYGQGMTIAALEALTLRECLRAGDALLAQRFFRATTQYIGATWAINQARDRTTSGVYHGMRQRLQGWISRATLNASTQDVVLTERCFRVFNFIDPPSRLRDPALLPRIVWGNLRARFVAKRHRSETAPVGPASPPGNRIAVRS
>NC_008595.1|WP_003872245.1|2318403_2319792_+|3-deoxy-7-phosphoheptulonate-synthase-class-II
MNWTVDIPIDQLPPLPPLPGDLRARLDAALAKPAAQQPSWPTDQATAMRTVLESVPPVTVPSEIVRLQEQLAQVARGEAFLLQGGDCAETFTENTEPHIRGNIRTLLQMAVVLTYGASMPVVKVARIAGQYAKPRSADIDALGLKSYRGDMINGFAPNAAVREHDPSRLVRAYANASAAMNLVRALTSSGLASLHLVHDWNREFVRTSPAGARYEALATEIDRGLRFMSACGVADRNLQTAEIYASHEALVLDYERAMLRLSDSDAGEPQLYDLSAHTVWIGERTRQLDGAHIAFAEVIANPIGVKIGPTITPELAVEYVERLDPHNKPGRLTLVSRMGNSKVRDLLPPIVEKVQATGHQVIWQCDPMHGNTHESSNGYKTRHFDRIVDEVQGFFEVHRALGTHPGGIHVEITGDNVTECLGGAQDISDMDLVGRYETACDPRLNTQQSLELAFLVAEMLRD
>NC_008595.1|WP_009976539.1|2317823_2318312_+|polyadenylate-specific-3'-exoribonuclease-AS
MRYFYDTEFIEDGRTIELISIGVVAEDGREYYAVSTEFDPERAGPWVRANVLPKLPPPASQLWRSRRQIRDDLEEFFGVRAAQSEPIELWAWVAAYDHVALCQLWGPMPDLPRAIPRFTRELRQLWEDRGCPRMPPRSPDAHDALVDARDQLRRFRIITGAG
>NC_008595.1|WP_019685223.1|2316918_2317803_+|hypothetical-protein
MLHSFVSEVTRWFAHDVYDRGHLPLLCCLVAFILTFFVTRSFVRFIRHRAETGRPARWWHPRNVHVGGVHIHHVTFGVVLTLLSGLTLVTLSINGHEPEFTVAATFFGIGAALVLDEYALILHLSDVYWSEDGRTSVDAVFAAVAVGGLLIMGLHPLMFFLPMWHGADSMMLRALVGGAMVLTLPLAVVVVLKGKVWTGLLGMFLVVLLVIGAVRLSRPHAPWARWRYSTQPEKMRRALQRERTLRRPVVRAKLYLQCAIAGTPRFPDERTVDATLDHEVHPAPAPTGPILIGR
>NC_008595.1|WP_010949412.1|2315537_2316827_-|DUF2029-domain-containing-protein
MSTRQAPGAGFPGKRPGWALWWGLAWLTAAAALGYAAWQLFGHTPYRIDIDVYQMGARAWMDGRPLYRGDVLFHTPIVDLPFTYPPLAAIVFCPFAWMHMPTASVAITALTLVLLVVSTVIVLARLDVWSTSALLPGPAWLRRWWLAVVVAAAATIWLEPISSNFAFGQINVVLMTLVIADCLPRRTPWPRGLLLGLGMALKLTPAVFLLYFLLRRDHRAVLTALASFAGATLLGFVLAYTDSWEYWTHTVHHTDRIGSASLNTDQNIAGALARLGLAQQPRSLLWVAASLLVLAVTVWAMRRVLRADEPTLALVCVALFGLVVSPVSWSHHWVWVLPTVLVTGVLGWRRRNAALLVLSVVGVALMRWTPIDLLPKHHEASAVWWRQLAGMSYVWWALAVIVAAGVTVTARAASRDAAPQQLTPVTAIG
>NC_008595.1|WP_009976536.1|2314815_2315541_+|1-acyl-sn-glycerol-3-phosphate-acyltransferase
MWYWLFKYVLLGPLLSLLGRPKVEGLEHVPSSGPAILASNHLAVMDSFYLPLVVRRRITFLAKSEYFTGTGLKGWFQRWFFTAVGQVPIDRTDADSAQAALTTAQQVLAQGKLLGMYPEGTRSPDGRLYKGKTGLARLALQTGVPVIPVAMIGTNVVNPPGSNMLRFGRVTVRFGKPMDFSRFEGLAGNRFIERAVTDEVIYELMGLSGQEYVDIYAASLKKGGAEAPGDEAARIPETAAG
>NC_008595.1|WP_011724718.1|2314338_2314728_+|hypothetical-protein
MSGAHPDIGPELRRLAQSILDGIDPAVRAAAALTAGAGPGTGKCQQVWCPVCALAALATGDQHPLLTAIADHSIALLEVIRDIVADIDRASGPTPGPPPDGPPGGAPDTPDTGQAPRTRYQPIPVTFEE
>NC_008595.1|WP_085988250.1|2313061_2314342_+|ArsA-family-ATPase
MSESGASSAPTPARISLFVGKGGVGKSTLACATAVAAAGAGQRVLVVSTDQAHSLGDVLGVPVPPSQAELVRVLADLETGRAEAGGGFLDALALDTLALLEARWRDVVAALDRRFPDSELSTIAPEELSALPGVQEVLGLHAVGELARSGRWDRVVVDCASTADALRMLTLPATFGLYVERAWPRHRRLSLTAEDARSAAVVELLERVSASVEALSALLTDGDLVGAHLVLTPERVVAAEAARTLGSLALMGVRVEELIVNQVLLQDDSYEYRNLPEHPAFYWYTERIAEQQSVLEELDAAIGEVALVLTPHLSGEPIGPKALGALLDAARRRGGAAPPGPLRPTVDLESGTGLGSIYRMRLALPQLDPSALTLGRVDDDLIISAGGLRRRVRLASVLRRCTVLDAHLRGSELTVRFRPDPEVWPK
>NC_008595.1|WP_009976532.1|2312631_2313069_+|SRPBCC-family-protein
MAEKTTQTIYIEADPDTVMKVIADIDSYPRWISEYKEAEVVEKDADGYPKVARIVMDATVLKDTMVMSYQWPKDRRSVSWTLVSSSLLRALEGSYRLAPKGSGTEVTYELSVDLAMPMIGLLKRKAERRLTDTALKDLKKRVEAE
>NC_008595.1|WP_003878126.1|2322734_2323139_+|DNA-binding-protein
MSSIPAGDDVLDPDEPIYDLPRVAELLGVPVTKVHQQLREGHLVAVRRGEALVVPQVFFTKSGEVVKSLPGLLTILHDGGYRDTEIVRWLFTRDPSLTVTRDGSRDAISNARPVDALHAHQAREVVRRAQAMAY
>NC_008595.1|WP_011724723.1|2323132_2324650_-|alpha-(1-6)-mannopyranosyltransferase-A
MATGTDTPAADPPAAKPSRGQWFSRLKAFAGSADSGPAKLGMLGSVLITLGGLGAGSTRQHDPLLESIHMSWLRFGHGLVLSSIVLWTGVGLMLIAWLSLGRRVLAGEATEFVMKATTGFWLAPLLVSVPVFSRDTYSYLAQGALLRDGLDPYAVGPVANPNSLLDNVSPIWSITTAPYGPVFILVAKIITILVGNNVVAGTALLRLCMLPGLVLLIWATPRLARHLGADEPTALWICVLNPLVLIHLMGGVHNEMLMVGLMAAGIALTFGGRPVAGVTLITVAIAVKATAGIALPFLVWVWARQLRDQRGYRPVPAFFAATAASLLIFAVVFAALSAVAGVGLGWLTALAGSVKIINWLTVPTAAANLIHAIGSGFFPVSFYPILRVTRLVGIAIIAISLPLLWWRFRRDDRDALTGIAISMLIVVLFVPAALPWYYSWPLAVLAPLAQSRRAVAIIGGLSTWVMVIFKPDGSHGMYSWLHFSLATAVALVAWYSLYRVPQPAQ
>NC_008595.1|WP_003872240.1|2324654_2325704_-|polyprenyl-synthetase-family-protein
MTGAITEQLRRYLHDRRAETAYIGDDYSGLIAALEEFVLNGGKRLRPAFAYWGWRAVATEAPDDQALLLFSALELLHACALVHDDVIDDSATRRGRPTTHVRFASLHRDRQWQGSPERFGMSAAILLGDLALAWADDIVLGVDLTPQAARRVRRVWANIRTEVLGGQYLDIVAEASAAASIASAMNVDTFKTACYTVSRPLQLGAAAAADRPDVHDLFSQFGTDLGVAFQLRDDVLGVFGDPAVTGKPSGDDLRSGKRTVLLAEAVELAEKSDPLAAKLLRDSIGAQLSDAEVDRLRDVIESVGALAAAEQRIATLTQRALATLAAAPINTAAKAGLSELAKLATNRSA
>NC_008595.1|WP_003872239.1|2325969_2326863_+|hypothetical-protein
MTLNTIALELVPPNADEGRERALEEAHKVVRHSAESGLDGRIRHVMIPGIIAEDDDRPVPMKPKLDVLDFWSVVKPELPGIKGLCTQVTAFMDEQSLHGRLTELCSAGMEGVVFVGVPRTMNDGEGSGVAPTDALSIYRDLVTNRGVILIPTRDGEQGRFSFKCDRGATYGMTQLLYSDAIVGFLREFARQTDHRPEILLSFGFVPKMESRVGLINWLIQDPGNAAVAREQEFVKTLAASEPAQKRRQMVDLYKRVIDGVGDLGFPLSIHLEATYGISGPAFQTFAEMLAYWSPRPS
>NC_008595.1|WP_003872238.1|2326866_2327547_-|DUF3153-domain-containing-protein
MRRRRLLAFAMLLLVVPLATGCLRVRASLTISPDDLVSGEIVAAAKPKTPKDTGPQLDSNNLPFSQKVAVSNYDSDGYVGSQAVFSDLTFAELPQLANMNSDAAGVNLSLRRNGNLVLLEGRADLTSLTDPEADVELTVAFPGVVTSTNGDRVEPDVVSWKLKPGVVSTMTAQARYTDPNTRSFTGAVVWLGIASFAAAGVVGLLAWVSRDRSPRLTAPRDQPPPE
>NC_008595.1|WP_011724724.1|2327666_2328269_-|GNAT-family-N-acetyltransferase
MAIFLIDLLPHDMERRLGDALAVYVDAMRYPRGTENQRAAMWLEHIRRRGWQGAAVVEAEVDYDDQMPSAEELASAPLLGVAYGYPGAPGQWWQQQVVLGLQRGGSPPQEIARLMNDYFELTELHIHPRAQGRGLGEALARRLLAGRAEKNVLLSTPETNGEPNRAWRLYRRLGFTDIIRRYHFAGDPRPFAILGRELPL
>NC_008595.1|WP_011724725.1|2328661_2329063_+|DUF3040-domain-containing-protein
MPLSDHEQRMLDQIESALYAEDPKFASSVRGGGFRAPTARRRLQGVALFVIGLAMLVSGVAFKATMIGNFPILSVFGFIVMFGGVVFAITGPRLPGRPDLSGSAPTSLRQRRNRSGGSFTSRMEDRFRRRFDD
>NC_008595.1|WP_003872235.1|2329499_2329931_+|division/cell-wall-cluster-transcriptional-repressor-MraZ
MFLGTYTPKLDDKGRLTLPAKFRDALAGGLMVTKSQDHSLAVYPRAEFEQLARRASKASKSNPDARAFLRNLAAGTDEQHPDAQGRITLSADHRRYASLSKDCVVIGAVDYLEIWDAQAWQDYQQTHEENFSAASDEALGDII
>NC_008595.1|WP_095785446.1|2329905_2331066_+|16S-rRNA-(cytosine(1402)-N(4))-methyltransferase-RsmH
MKHSATSSEAHARATWPLPEPTLAYFPNARFVPSDRDLDAGAARPIRGGVAVVDDSPDFGHVPVLLERCVELLTPALTRRHPDGSGAVLLDATLGAGGHAERFLTDLPGLRLIALDRDPSALEIARERLARFADRITLVHTRYDGIAAALTESGYAATESVDGILFDLGVSSMQLDRPERGFAYAQDAPLDMRMDPGSPLTAADILNTYDEAELADILHRYGEERFARRIAAQIVRRRAKEPFTSTADLVSLLYQAIPAPARRTGGHPAKRTFQALRIAVNDELDTLRCALPAALDALAVDGRIVVLAYQSLEDRIVKRLFAQAVASRTPVDLPVELPGHEPRFRALTHGAGRADAAEIERNPRSAAVRLRALQRTQAPQATGKGD
>NC_008595.1|WP_011724728.1|2331065_2332340_+|hypothetical-protein
MKAERETAKRRGGSDRRGARDGSARRGRRPAADAGAARRARGGPASAPTRESRAPKPGPQTSPVARPAERSARPKNTSQAKARAKARKAKAPKVVRPRLTERLAARLAAIDLRPRTLASKVPFVVLVIGALGVGLGLTLWLSTDSAERSYKLSHARERTRLLQQQKEALERDVREAEAAPALAEAARKQGMIPTRDTAHLVQDPSGNWVVVGTPKPADGVPPPPLNSKLPDEAPQPPKPAPPAAEVPIRVELAPGGPVPARSGPEALLRAPDGASTLGGQHLAPAVPPVPGTPPGVPGGPVAAPPALPGGPVAAVPPASPAMPTGPATGRPPGLTPGLPMPGLPMPAGPAVAPAPAEVSIPLGGLPVPAPGQLPAPLPPEVPVPVQLGRPGAAPQPVVPAAPLPQPVNGAQPGAAPVASPGAPR

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Crispr_ID: NC_008595_4

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_008595_4

2505613-2505719

Orphan

Consensus_repeat	Method
CGTTCGAGTGCCGCTTCGGCGTACGGCGCGCCGCGTTCGGC	CRISPRCasFinder

1 spacers

The CRISPR arrays of NC_008595_4

>merge|NC_008595|4|2505613-2505719|CRISPRCasFinder
CGTTCGAGTGCCGCTTCGGCGTACGGCGCGCCGCGTTCGGCGGCCGTGCTGGCCAATTCGCGGCCGCGTTCGAGTGCCGCCTCGGCGTACGGCGCGCCGCGTTCGGC

>NC_008595|4|4|2505613-2505719|CRISPRCasFinder
CGTTCGAGTGCCGCTTCGGCGTACGGCGCGCCGCGTTCGGC	GGCCGTGCTGGCCAATTCGCGGCCG
CGTTCGAGTGCCGCCTCGGCGTACGGCGCGCCGCGTTCGGC

Protein	Signature genes	Signature genes Name	Protein_function
NC_008595.1\|WP_011724807.1\|2498048_2499272_+\|cytochrome-P450	unknown	unknown	gnl\|CDD\|225035
NC_008595.1\|WP_011724813.1\|2507788_2508139_-\|membrane-protein	unknown	unknown	gnl\|CDD\|379266
NC_008595.1\|WP_011724812.1\|2506974_2507775_+\|steroid-Delta-isomerase	unknown	unknown	gnl\|CDD\|366932
NC_008595.1\|WP_029248479.1\|2512406_2513492_+\|sn-glycerol-3-phosphate-ABC-transporter-ATP-binding-protein-UgpC	unknown	unknown	gnl\|CDD\|236947
NC_008595.1\|WP_009976733.1\|2510630_2511575_+\|sugar-ABC-transporter-permease	unknown	unknown	gnl\|CDD\|224096
NC_008595.1\|WP_011724811.1\|2506414_2506975_+\|pyrazinamidase-PncA	unknown	unknown	gnl\|CDD\|238493
NC_008595.1\|WP_009976717.1\|2497325_2497955_-\|TetR/AcrR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|366102
NC_008595.1\|WP_009976725.1\|2504233_2504623_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|314732
NC_008595.1\|WP_011724815.1\|2509305_2510634_+\|sugar-ABC-transporter-substrate-binding-protein	unknown	unknown	gnl\|CDD\|270303
NC_008595.1\|WP_009976737.1\|2514479_2514767_-\|DUF3349-domain-containing-protein	unknown	unknown	gnl\|CDD\|371747
NC_008595.1\|WP_011724814.1\|2508307_2509240_+\|sigma-70-family-RNA-polymerase-sigma-factor	unknown	unknown	gnl\|CDD\|236600
NC_008595.1\|WP_003876749.1\|2504653_2505232_+\|AAA-family-ATPase	unknown	unknown	gnl\|CDD\|226648
NC_008595.1\|WP_011724809.1\|2501664_2503662_+\|phosphotransferase	unknown	unknown	gnl\|CDD\|367273
NC_008595.1\|WP_011724806.1\|2496709_2497318_+\|hypothetical-protein	unknown	unknown	unknown
NC_008595.1\|WP_009976719.1\|2499369_2500035_-\|hypothetical-protein	unknown	unknown	unknown
NC_008595.1\|WP_011724805.1\|2495518_2496601_+\|dihydrodipicolinate-reductase	unknown	unknown	gnl\|CDD\|226326
NC_008595.1\|WP_003876738.1\|2513485_2514454_+\|patatin-like-phospholipase-family-protein	unknown	unknown	gnl\|CDD\|132846
NC_008595.1\|WP_010949355.1\|2503658_2504153_+\|gluconokinase	unknown	unknown	gnl\|CDD\|225804
NC_008595.1\|WP_011724808.1\|2500128_2501646_+\|carboxylesterase/lipase-family-protein	unknown	unknown	gnl\|CDD\|225181
NC_008595.1\|WP_003876741.1\|2511561_2512404_+\|carbohydrate-ABC-transporter-permease	unknown	unknown	gnl\|CDD\|223472

Protein	Function_ID	Function_description	E-value
NC_008595.1\|WP_011724807.1\|2498048_2499272_+\|cytochrome-P450	gnl\|CDD\|225035	COG2124, CypX, Cytochrome P450 [Secondary metabolites biosynthesis, transport, and catabolism].	1.3283e-77
NC_008595.1\|WP_011724813.1\|2507788_2508139_-\|membrane-protein	gnl\|CDD\|379266	pfam13564, DoxX_2, DoxX-like family. This family of uncharacterized proteins are related to DoxX pfam07681.	2.42425e-10
NC_008595.1\|WP_011724812.1\|2506974_2507775_+\|steroid-Delta-isomerase	gnl\|CDD\|366932	pfam02136, NTF2, Nuclear transport factor 2 (NTF2) domain. This family includes the NTF2-like Delta-5-3-ketosteroid isomerase proteins.	1.9018e-09
NC_008595.1\|WP_029248479.1\|2512406_2513492_+\|sn-glycerol-3-phosphate-ABC-transporter-ATP-binding-protein-UgpC	gnl\|CDD\|236947	PRK11650, ugpC, sn-glycerol-3-phosphate ABC transporter ATP-binding protein UgpC.	0
NC_008595.1\|WP_009976733.1\|2510630_2511575_+\|sugar-ABC-transporter-permease	gnl\|CDD\|224096	COG1175, UgpA, ABC-type sugar transport systems, permease components [Carbohydrate transport and metabolism].	9.86745e-95
NC_008595.1\|WP_011724811.1\|2506414_2506975_+\|pyrazinamidase-PncA	gnl\|CDD\|238493	cd01011, nicotinamidase, Nicotinamidase/pyrazinamidase (PZase). Nicotinamidase, a ubiquitous enzyme in prokaryotes, converts nicotinamide to nicotinic acid (niacin) and ammonia, which in turn can be recycled to make nicotinamide adenine dinucleotide (NAD). The same enzyme is also called pyrazinamidase, because in converts the tuberculosis drug pyrazinamide (PZA) into its active form pyrazinoic acid (POA).	6.21413e-70
NC_008595.1\|WP_009976717.1\|2497325_2497955_-\|TetR/AcrR-family-transcriptional-regulator	gnl\|CDD\|366102	pfam00440, TetR_N, Bacterial regulatory proteins, tetR family.	1.50585e-09
NC_008595.1\|WP_009976725.1\|2504233_2504623_+\|hypothetical-protein	gnl\|CDD\|314732	pfam11903, ParD_like, ParD-like antitoxin of type II bacterial toxin-antitoxin system. ParD-like antitoxin is a family of archaeal and bacterial proteins of a type II bacterial toxin-antitoxin system. Many of the cognate toxins for these molecules fall into family ParE-like_toxin, pfam15781. Gene-pairs are expressed from the same operon, the toxin of the pair being expressed first, eg, for UniProtKB:Q3AQ93 and UniProtKB:Q3AQ94.	1.43668e-14
NC_008595.1\|WP_011724815.1\|2509305_2510634_+\|sugar-ABC-transporter-substrate-binding-protein	gnl\|CDD\|270303	cd13585, PBP2_TMBP_like, The periplasmic-binding component of ABC transport systems specific for trehalose/maltose and similar oligosaccharides; possess type 2 periplasmic binding fold. This family includes the periplasmic trehalose/maltose-binding component of an ABC transport system and related proteins from archaea and bacteria. Members of this group belong to the type 2 periplasmic-binding fold superfamily. PBP2 is comprised of two globular subdomains connected by a flexible hinge and bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap. The majority of PBP2 proteins function in the uptake of small soluble substrates in eubacteria and archaea. After binding their specific ligand with high affinity, they can interact with a cognate membrane transport complex comprised of two integral membrane domains and two cytoplasmically located ATPase domains. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis.	2.4152e-75
NC_008595.1\|WP_009976737.1\|2514479_2514767_-\|DUF3349-domain-containing-protein	gnl\|CDD\|371747	pfam11829, DUF3349, Protein of unknown function (DUF3349). This family of proteins are functionally uncharacterized. This protein is found in bacteria. Proteins in this family are typically between 99 to 124 amino acids in length.	2.78501e-24
NC_008595.1\|WP_011724814.1\|2508307_2509240_+\|sigma-70-family-RNA-polymerase-sigma-factor	gnl\|CDD\|236600	PRK09636, PRK09636, RNA polymerase sigma factor SigJ; Provisional.	4.61848e-58
NC_008595.1\|WP_003876749.1\|2504653_2505232_+\|AAA-family-ATPase	gnl\|CDD\|226648	COG4185, COG4185, Uncharacterized protein conserved in bacteria [Function unknown].	9.75582e-70
NC_008595.1\|WP_011724809.1\|2501664_2503662_+\|phosphotransferase	gnl\|CDD\|367273	pfam02958, EcKinase, Ecdysteroid kinase. This family includes ecdysteroid 22-kinase, an enzyme responsible for the phosphorylation of ecdysteroids (insect growth and moulting hormones) at C-22, to form physiologically inactive ecdysteroid 22-phosphates.	7.60065e-25
NC_008595.1\|WP_003876741.1\|2511561_2512404_+\|carbohydrate-ABC-transporter-permease	gnl\|CDD\|223472	COG0395, UgpE, ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism].	1.10088e-86
NC_008595.1\|WP_011724805.1\|2495518_2496601_+\|dihydrodipicolinate-reductase	gnl\|CDD\|226326	COG3804, COG3804, Uncharacterized conserved protein related to dihydrodipicolinate reductase [Function unknown].	4.46069e-65
NC_008595.1\|WP_003876738.1\|2513485_2514454_+\|patatin-like-phospholipase-family-protein	gnl\|CDD\|132846	cd07207, Pat_ExoU_VipD_like, ExoU and VipD-like proteins; homologus to patatin, cPLA2, and iPLA2. ExoU, a 74-kDa enzyme, is a potent virulence factor of Pseudomonas aeruginosa. One of the pathogenic mechanisms of P. aeruginosa is to induce cytotoxicity by the injection of effector proteins (e.g. ExoU) using the type III secretion (T3S) system. ExoU is homologus to patatin and also has the conserved catalytic residues of mammalian calcium-independent (iPLA2) and cytosolic (cPLA2) PLA2. In vitro, ExoU cytotoxity is blocked by the inhibitor of cytosolic and Ca2-independent phospholipase A2 (cPLA2 and iPLA2) enzymes, suggesting that phospholipase A2 inhibitors may represent a novel mode of treatment for acute P. aeruginosa infections. ExoU requires eukaryotic superoxide dismutase as a cofactor and cleaves phosphatidylcholine and phosphatidylethanolamine in vitro. VipD, a 69-kDa cytosolic protein, belongs to the members of Legionella pneumophila family and is homologus to ExoU from Pseudomonas. Even though VipD shows high sequence similarity with several functional regions of ExoU (e.g. oxyanion hole, active site serine, active site aspartate), it has been shown to have no phospholipase activity. This family includes ExoU from Pseudomonas aeruginosa and VipD of Legionella pneumophila.	3.46279e-64
NC_008595.1\|WP_010949355.1\|2503658_2504153_+\|gluconokinase	gnl\|CDD\|225804	COG3265, GntK, Gluconate kinase [Carbohydrate transport and metabolism].	1.0697e-68
NC_008595.1\|WP_011724808.1\|2500128_2501646_+\|carboxylesterase/lipase-family-protein	gnl\|CDD\|225181	COG2272, PnbA, Carboxylesterase type B [Lipid metabolism].	0

>NC_008595.1|WP_003876749.1|2504653_2505232_+|AAA-family-ATPase
MERLDVVVGPNGAGKSTFIALTLAPLLPGSVVVNADEIARQRWPQDPASHAYDAAKVAADTRAKLIDLGRSFIAETVFSHPSKLDLLHAARRAGFTVVLHVLLIPEDLAVERVRHRVRAGGHDVPETKIRERHRRLWTPVAEAMTLADLATGYDNSRLRGPRVVARLSGGLTVGAVDWPAWAPETLRSRWPV
>NC_008595.1|WP_009976725.1|2504233_2504623_+|hypothetical-protein
MAEAVDRVTRVASDLMDSAAAEGARQSRSAKQQLDHWARVGRAVSSQHTASRRRVEAALAGRLSTAELTVEEGVVFNAEISAAIDESLARTNYGATLAGQGVTTVALNDDGEIVEHRPDGTAVVLAGRR
>NC_008595.1|WP_010949355.1|2503658_2504153_+|gluconokinase
MSGSAPVVVMGVSGSGKSTVGVTLARRLRVPFVDADTLHPPANIAKMAAGTPLGDDDRRPWLDEVGEWLAAHRDGGVAACSALKRAYRDRLRAHCPDVAFLHLSGSAALLGPRLAARSGHFMPAALLQSQLDALEPLGPDEAGLTVDAGREVDSIVDVVLRARR
>NC_008595.1|WP_011724809.1|2501664_2503662_+|phosphotransferase
MHAETEQVIERPSDLSASWLAAVIGTGPIADFSVERIGTGQMSECYRIRLRYAQADARGPESVVLKVAATDPVSRQTGLALGLYEREVRFYGDVAPRLGGPIAPCYHAAVDTSTGVFDLLLGDAGPAVVGDEIAGATIEQARLGVVELGRLHGPLLGDISLAQAPWLNRDAPLNQAMIAPLYAGFVERYGDQIAPEHRAVCERLVAAFDGYLAQEPGVRGLVHGDYRLDNMLFGTAGAERALTVVDWQTVSWGPALTDLAYFLGCALPTEDRREHYDALLRAYHEALGPQPPITLADVADGVRRQSFFGVMMAIVSSMLVERTDRGDQMFMTMLRRHCDHVLDTDALATLPAASAPEPLQPSPEDELAHDPTTEPLWSESWYADFADPAQGLGGWFRLGLVANQQTAWVHALVCGPDMPTVAVDAQVPLPPDPWTVRTDTFEITHSAGAPLRSYRVDVRALAQAYADPAALLRGEPGTPVAMTMNLDWHTDGTPYKYAMTTRYEIPCTVTGSVTIGDTAYRIESVAGQRDHSWGVRDWWSMDWIWSALHLDDGTHLHGVNIRIPGAPAFSIGYTQGADGEVTELQTVDSRESFGDNGLPLDATLELNPGEITAQVDVRGQAPVRLVAADGRVSQFPRVWAAVSTGDGRRGVGWLEWNRNLGERIG
>NC_008595.1|WP_011724808.1|2500128_2501646_+|carboxylesterase/lipase-family-protein
MHDRTVRARTATGIVEGFTRDGVHRWRSIPYARPPVGDLRFRAPQPAQPWSGVRHCHGFANCAPQQRRYTLLGLSGLGGRYQPMSEDCLTLNVVTPEAPAEGPLPVMVFIHGGGYFLGSSATPLYDGAALARRGCVYVSVNYRLGALGCVDFSSLSTPEIPLESNLYLRDLVLALQWVRDNIAEFGGDPDNVTIFGESAGACITATLLAVPAAKGLFAQAISESPASGLVRSQEVAAEFANRFANLLGVRRQDAANALMQASAAQLVKTQHRLIDEGMQDRLGAFPIGPVVGDDILPTDPVEAMRRGEAHRVPLIVGTNAEEGRLFTRFLAMLPTNESMVEELLADAEPAVRERITAAYPDYPDRSACIQLGGDFAFGSAAWQIAEAHCAHAPTYLYRYDYAPRTLRWSGFGATHATELLAVFDVYRTRFGALLTAAADRRAALRVSNQVQRRWRAFSRTGVPGEDWPRYTAADRAVLVFDRKSRVEFDPHPHRRMAWDGFSLAR
>NC_008595.1|WP_009976719.1|2499369_2500035_-|hypothetical-protein
MIAASVLVAGCAHTTGGRSEPTPSGAATPSGSAAGPSSSKPPGPSGAPAAGAAMSDVITWIEAGHPADPSRYHTATRDGVATPLGDDIAVSALAGKVSCMTDAKHTGGAVVCLVSLTHPAPPPATAYGQWQGGWVDFDGTSLQVGSARADPGPFVNGNGTELANGDSLAFGEYRCRADQAGLYCVNYARQSAAKLSPAGVEPFGCLRSTPPPDGVGAAFSC
>NC_008595.1|WP_011724807.1|2498048_2499272_+|cytochrome-P450
MSISFETSESRADAELPVLPMPRAAHCPLAPPPEFVDWRQQPGLRRALFQGNPVWVVSRYHDIRAALVDPRLSAKTIPDSIMPTDADNKVPVMFARTDDPEHHRLRRMLTGNFTFRRCESMRPQIQDTVDHYLDRMVDGGVPADLVREFALPVPSLVIALLLGVPPEDLELFQFNTTKGLDQKSSDEEKGKAFGAMYAYIEELVQRKAREPGDDLISRLITEYVATGQLDHATTAMNSVIMMQAGHETTANMISLGTVALLGHPEIYARLGQTDDSAVVANIVEELMRYLSIVHSQVDRVATEGLTIAGQLIRAGEFVVMNLPAGNWDTEFVDNPESFDADRNPRGHLGFGYGVHQCIGANLARVEMQVAFATLARRLPGLRLAVPPEQLKFKDANIYGMKELPVSW
>NC_008595.1|WP_009976717.1|2497325_2497955_-|TetR/AcrR-family-transcriptional-regulator
MTAVEDRPLRSDAARNVERILRAAREVYAELGPDAPVEAVARRAGVGERTLYRRFPAKADLVRAALDQSIAEDLTPVIDSARHAKDPLHGLTRLVEAAISLGAREQNLLAAAHRAGSLTSDISVSLNEALGELVREGQRAGRIRADLVADDLPRLVAMLYSVLSTMDAGSEGWRRYVALVVDAISVDERRPLPPAAALRYASQPNSWPL
>NC_008595.1|WP_011724806.1|2496709_2497318_+|hypothetical-protein
MTKVRTSALGLTATAVLVGATVVGCGGDKNPAASSSPAASTPSAASPSAGAPADYSNLLIKPGDVGPNATADGPPSQNPSGITGVGQVFKNPDGKRTIMDTIAVFPDPATAAQTAANMRDVVGKKVNGPQQPIDIGSNGFMVIGQGSDPANPMEISEAVFVEGRAMVDLESDCVIGNPTPADVLLDLARKQDAAVKAGLPAG
>NC_008595.1|WP_011724805.1|2495518_2496601_+|dihydrodipicolinate-reductase
MRRVIQFSTGNVGRHSLRAIIGRPDLELVGVHAAGPEKIGRDAAQLCGLDEPTGIIATDDIDALVALNADCVVYTSQGETRPMEAIEQMSRFLAAGTNVVGTSMVWLVAPRHAEEWLREPLQRACEAGNTSLYVNGIDPGFSGDTLVHAAVSLATRVSSITVQEIFDYGNYDDAEFTGAAMGFGTAPDDDSPMMFLPGVIVAMWGGQVRSLADHLGVELDDVRQRIERWFTPERIDCTMMTVQPGRMAAVRFATEGVRDGEPVITLEHVTRLTRAAAPDWEYPPDGHTGVHRVVVAGEPRVEINTHVSHPLFDSTDAGCISTAARVVNAIDWVCRAPQGLIGVEDIPLAATMRGVLWQDR
>NC_008595.1|WP_011724811.1|2506414_2506975_+|pyrazinamidase-PncA
MRALIIVDVQNDFCEGGSVPVAGGAAVAPAINAYLDDAPGYDYVVATQDFHIDPGDHFSDRPDYSSSWPAHCLAGSAGADFRPELDTTRVDAVFRKGAYAAGYSGFEGVDDNGTPLLEWLRRRGVDEVDVVGIATDHCVRRTAEDAARAGLTTRVLVHLTAAAAEDSAARALDEMRSAGIELVGAR
>NC_008595.1|WP_011724812.1|2506974_2507775_+|steroid-Delta-isomerase
MVAPLDRQQLLAAVERSPQAAAEHDRAAWVALFTPDGRIEDPVGSRPHLGRTQIGRFYDTFIAPRDIRFHRDLDVVFGTTVLRDLELEVAMGPTVTMYIPAFLRYDLRETNGEWLIGALRAYWELPAMMVQFLRSGPGAARPAVDLCRGLLRNQGWRGSAGFMAGFRRVGAPHQRLVRRFLDAVAAGDKFAAAQALSSTAAITLGDRDPIELAELAEQLAGAGLTKMNSAGPAVAVSLHSGHGRAIMFADVAWRANAINRIRYFPA
>NC_008595.1|WP_011724813.1|2507788_2508139_-|membrane-protein
MNTVFVGITLFTAAITAAIAVADFVPARFVLANSAEVGVPRSWLPALGAAKLAGAAGLVVGLLGLPALGIAAAAGLVVFFVGAVLTHLRAGVLYNIAFPGAYLCLSAASLAWMALR
>NC_008595.1|WP_011724814.1|2508307_2509240_+|sigma-70-family-RNA-polymerase-sigma-factor
MNAPRNLAELAQRFDDDRRHLRSVAFQLLGSLADADDAVQSAWLKASRADFAAVDNLSGWFTTITAREALDQLRARKRRAELPLAAPEELDRLAVAASSPADEDTLLAESVSTALLVVLDRLSPAQRVAFVLHDVFAMPFETIAELLNRSPDAAKKLASRARARLHAAPAGPPRRDGHRIERHVEVVQAFLAASRGGDIAALLQLLAADVLRTVDPVLVPADVPTALRGATRVAQETRRFAGRARAGAVMLIDGTPGIVIAARGRAQILLMIGIGADDRIHTIDITGDPERIRRAALALPPAVRFRNITT
>NC_008595.1|WP_011724815.1|2509305_2510634_+|sugar-ABC-transporter-substrate-binding-protein
MLDRPFGRRSLLRGAGALSAAALAPWSAGCGSDDDGALTFFFAANPEERDARMRIIDEFARRHPDIKVRAVLSGPGVMQQLSTFCVGGRCPDVLMAWELSYAELADRGVLLDLGPLLARDKAFAQQLQADSIPALYETFTFNGKQYALPEQWSGNYLFYNKRLFDEAGVPSPPTAWERPWDFSEFLDTARALTKRDASGRAAQYGFVNTWGSYYSAGLFAMNNGVPWSDPRLNPTHFNFDNAAFQEAVQFYADLANKYRVAPNASETQSMSTPNLFAVGRAAMALGGHWRYQTYLRAEGLDFDVAPLPVGPAVGKGQPACSDIGATGLAISSSSPRKEQAWEFVKFATGPVGQALIGESCLFVPVLRSALKSDGFARAHRRVGNLGVLTDGPAFSQGLPITPAWEKVNALMDRNFGPILRGSRPATSLAGLSRSVDEVLRSP
>NC_008595.1|WP_009976733.1|2510630_2511575_+|sugar-ABC-transporter-permease
MTALDTEAGRRTPKNPSPWRRHAWAGRLFVAPNMVAVAVFMLFPLGFSLYMSFQRWDVFTPPKFVGLKNFTDLFSSDPLFLIAIRNTVIFTLGSVVPTVAISLAVAGVLNQKVRGIGIFRTIVFLPLAISSVVMAVVWQFVFNTDNGLLNIMLGWVGLGPVPWLVEPRWAMASLCIVSVWRSVPFATVVLLAAMQGVPETVYEAARIDGAGEIRQFFAITVPLIRGSISFVVIISIIHAFQAFDMVYVLTGPSGGPESATYVLGIMLFQHAFSFLEFGYASALAWVMFAVLLVLTVVQLRVSHRRSLETSRGLK
>NC_008595.1|WP_003876741.1|2511561_2512404_+|carbohydrate-ABC-transporter-permease
MGSSEAVIKRTVLRAATVYAALLGIAWCALFPIAWAVSGSLKTEGEVSEPTLVPARPRWSNYTEVFALMPIGRMFVNTVLYAGCVTAGHVFFCSLAGYAFARLDFRGRNTLFVVYLGTLMVPLTVTVIPQFLIMRTLGWVDTPWAMIVPGFFGSAFGTYLMRQFFRTLPTDLEEAAILDGCTPWQVYWRILLPHARPAVMVLAVLTWVNVWNDFLWPLLMIQRSSLATLTLGLVRMKGEYVARWPVLMAASMLIMLPLVIIYAIAQRSFVRGIAVTGMGG
>NC_008595.1|WP_029248479.1|2512406_2513492_+|sn-glycerol-3-phosphate-ABC-transporter-ATP-binding-protein-UgpC
MASVTFQQATRRYPGADRPALDNLNLVVGDGEFVVLVGPSGCGKTTSLRMVAGLETVDSGRILIGDRDVTNVDPKQRDVAMVFQNYALYPHMTVAQNMGFAMKIAKTPKAQIRERVLDAAKLLDLQPYLDRKPKDLSGGQRQRVAMGRAIVRRPQVFLMDEPLSNLDAKLRVQTRNQIAALQRRLGTTTVYVTHDQVEAMTMGDRVAVLRDGVLQQFAPPRELYRNPSNVFVAGFIGSPAMNLFTLPVVDSAVSLGDWPIALPREIAAAASEVVVGVRPEHFELGGLGVEMEVDVVEELGADAYLYGRITGSGKVIDAPIVARVDGRNPPEKGSRVRLHPAPGHLHFFGRNGQRIGVRGSW
>NC_008595.1|WP_003876738.1|2513485_2514454_+|patatin-like-phospholipase-family-protein
MVNTVRADLVCEGGGVRGIGLVGAVDALAAAGYRFPRVAGSSAGAVVASLVAALQTAGEPLSRLTDIMRTIDYRKFLDRNLIGHVPVIGGGLSLLTSDGVYRGAYLEQLLAGLLGDLGVRTFGDLRTGEAPEQFAWSLVVTASDLSRRRLVRIPWDLGSYGIDPDDFPVARAVHASSAIPYVFEPVRVGGATWVDGGLLSDFPVELFDRPDGQPQWPTFGIRLSARPGIPPTHPVHGPVSLGIAAIETLVSNQDNAYIDDPCTVRRTIFVPAEDVSPIDFDITAQQREALYERGRQAGQQFLQTWNYADYLKACGGPVPETP
>NC_008595.1|WP_009976737.1|2514479_2514767_-|DUF3349-domain-containing-protein
MDLAHWVTSIVAFVRAGYPAGMPATGHVPLVALAHRRLCHDDITAIATDLIARRLWPISSVDIGVEITRFTNQLPSPQDVDLVLRRVHAIRCSRG

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Crispr_ID: NC_008595_5

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_008595_5

2745832-2745930

Orphan

Consensus_repeat	Method
CGGTTGCGGCCCGACCCCCAGCGG	CRISPRCasFinder

1 spacers

The CRISPR arrays of NC_008595_5

>merge|NC_008595|5|2745832-2745930|CRISPRCasFinder
CGGTTGCGGCCCGACCCCCAGCGGCCGGCACACGTTGGCCGTCGGGTCCCACCATTGGCCCGGGTCGCAGGCCAACGGTTGCGGCCCGACCCCGAGCGG

>NC_008595|5|5|2745832-2745930|CRISPRCasFinder
CGGTTGCGGCCCGACCCCCAGCGG	CCGGCACACGTTGGCCGTCGGGTCCCACCATTGGCCCGGGTCGCAGGCCAA
CGGTTGCGGCCCGACCCCGAGCGG

Protein	Signature genes	Signature genes Name	Protein_function
NC_008595.1\|WP_009976824.1\|2751759_2752179_+\|Hsp20-family-protein	unknown	unknown	gnl\|CDD\|365807
NC_008595.1\|WP_011725000.1\|2752864_2754271_-\|acyltransferase	unknown	unknown	gnl\|CDD\|334202
NC_008595.1\|WP_024636750.1\|2738909_2739794_-\|alpha/beta-fold-hydrolase	unknown	unknown	gnl\|CDD\|131480
NC_008595.1\|WP_011724999.1\|2751266_2751647_-\|helix-turn-helix-transcriptional-regulator	unknown	unknown	gnl\|CDD\|133394
NC_008595.1\|WP_011724996.1\|2748197_2749373_+\|serine-hydrolase	unknown	unknown	gnl\|CDD\|224594
NC_008595.1\|WP_011724989.1\|2742474_2743185_-\|SDR-family-oxidoreductase	unknown	unknown	gnl\|CDD\|181044
NC_008595.1\|WP_011724987.1\|2737369_2738188_-\|CoA-transferase	unknown	unknown	gnl\|CDD\|224717
NC_008595.1\|WP_011724988.1\|2738295_2738889_+\|TetR/AcrR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|366102
NC_008595.1\|WP_011725003.1\|2755525_2756287_-\|SDR-family-oxidoreductase	unknown	unknown	gnl\|CDD\|235816
NC_008595.1\|WP_033711481.1\|2744822_2745224_+\|glyoxalase	unknown	unknown	gnl\|CDD\|319943
NC_008595.1\|WP_011725002.1\|2754920_2755478_+\|peptidylprolyl-isomerase	unknown	unknown	gnl\|CDD\|223619
NC_008595.1\|WP_009976825.1\|2752491_2752812_+\|J-domain-containing-protein	unknown	unknown	gnl\|CDD\|365959
NC_008595.1\|WP_011724993.1\|2745374_2745686_+\|DUF732-domain-containing-protein	unknown	unknown	gnl\|CDD\|368380
NC_008595.1\|WP_011724991.1\|2744026_2744869_+\|AraC-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|378964
NC_008595.1\|WP_011724986.1\|2736203_2737367_-\|acyl-CoA-dehydrogenase	unknown	unknown	gnl\|CDD\|173849
NC_008595.1\|WP_023861579.1\|2743365_2743803_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|366161
NC_008595.1\|WP_033722653.1\|2750763_2751207_+\|Hsp20-family-protein	unknown	unknown	gnl\|CDD\|365807
NC_008595.1\|WP_003876695.1\|2741775_2742429_-\|HD-domain-containing-protein	unknown	unknown	gnl\|CDD\|188314
NC_008595.1\|WP_011724997.1\|2749369_2750599_-\|tRNA-4-thiouridine(8)-synthase-ThiI	unknown	unknown	gnl\|CDD\|234960
NC_008595.1\|WP_009976816.1\|2746725_2748201_+\|biotin-carboxylase	unknown	unknown	gnl\|CDD\|180605

Protein	Function_ID	Function_description	E-value
NC_008595.1\|WP_009976824.1\|2751759_2752179_+\|Hsp20-family-protein	gnl\|CDD\|365807	pfam00011, HSP20, Hsp20/alpha crystallin family. Not only do small heat-shock-proteins occur in eukaryotes and prokaryotes but they have also now been shown to occur in cyanobacterial phages as well as their bacterial hosts.	1.2009e-29
NC_008595.1\|WP_011725000.1\|2752864_2754271_-\|acyltransferase	gnl\|CDD\|334202	pfam00668, Condensation, Condensation domain. This domain is found in many multi-domain enzymes which synthesize peptide antibiotics. This domain catalyzes a condensation reaction to form peptide bonds in non- ribosomal peptide biosynthesis. It is usually found to the carboxy side of a phosphopantetheine binding domain (pfam00550). It has been shown that mutations in the HHXXXDG motif abolish activity suggesting this is part of the active site.	3.46822e-19
NC_008595.1\|WP_024636750.1\|2738909_2739794_-\|alpha/beta-fold-hydrolase	gnl\|CDD\|131480	TIGR02427, b-ketoadipate_enol-lactone_hydrolase, 3-oxoadipate enol-lactonase. Members of this family are 3-oxoadipate enol-lactonase. Note that the substrate is known as 3-oxoadipate enol-lactone, 2-oxo-2,3-dihydrofuran-5-acetate, 4,5-Dihydro-5-oxofuran-2-acetate, and 5-oxo-4,5-dihydrofuran-2-acetate. The enzyme the catalyzes the fourth step in the protocatechuate degradation to beta-ketoadipate and then to succinyl-CoA and acetyl-CoA. 4-hydroxybenzoate, 3-hydroxybenzoate, and vanillate all can be converted in one step to protocatechuate. This enzyme also acts in catechol degradation. In genomes that catabolize both catechol and protocatechuate, two forms of this enzyme may be found. All members of the seed alignment for this model were chosen from within protocatechuate degradation operons of at least three genes of the pathway, from genomes with the complete pathway through beta-ketoadipate. [Energy metabolism, Other].	4.42319e-32
NC_008595.1\|WP_011724999.1\|2751266_2751647_-\|helix-turn-helix-transcriptional-regulator	gnl\|CDD\|133394	cd04766, HTH_HspR, Helix-Turn-Helix DNA binding domain of the HspR transcription regulator. Helix-turn-helix (HTH) transcription regulator HspR, N-terminal domain. Heat shock protein regulators (HspR) have been shown to regulate expression of specific regulons in response to high temperature or high osmolarity in Streptomyces and Helicobacter, respectively. These proteins share the N-terminal DNA binding domain with other transcription regulators of the MerR superfamily that promote transcription by reconfiguring the spacer between the -35 and -10 promoter elements. A typical MerR regulator is comprised of distinct domains that harbor the regulatory (effector-binding) site and the active (DNA-binding) site. Their conserved N-terminal domains contain predicted winged HTH motifs that mediate DNA binding, while the dissimilar C-terminal domains bind specific coactivator molecules.	1.95602e-36
NC_008595.1\|WP_011724996.1\|2748197_2749373_+\|serine-hydrolase	gnl\|CDD\|224594	COG1680, AmpC, Beta-lactamase class C and other penicillin binding proteins [Defense mechanisms].	8.35068e-33
NC_008595.1\|WP_011724989.1\|2742474_2743185_-\|SDR-family-oxidoreductase	gnl\|CDD\|181044	PRK07577, PRK07577, SDR family oxidoreductase.	2.04172e-140
NC_008595.1\|WP_011724987.1\|2737369_2738188_-\|CoA-transferase	gnl\|CDD\|224717	COG1804, CaiB, Predicted acyl-CoA transferases/carnitine dehydratase [Energy production and conversion].	4.27614e-45
NC_008595.1\|WP_011724988.1\|2738295_2738889_+\|TetR/AcrR-family-transcriptional-regulator	gnl\|CDD\|366102	pfam00440, TetR_N, Bacterial regulatory proteins, tetR family.	4.04646e-08
NC_008595.1\|WP_011725003.1\|2755525_2756287_-\|SDR-family-oxidoreductase	gnl\|CDD\|235816	PRK06500, PRK06500, SDR family oxidoreductase.	5.04616e-70
NC_008595.1\|WP_033711481.1\|2744822_2745224_+\|glyoxalase	gnl\|CDD\|319943	cd08355, TioX_like, Micromonospora sp. TioX and similar proteins. Micromonospora sp. TioX is encoded by a gene of the thiocoraline biosynthetic gene cluster. Thiocoraline is a thiodepsipeptide with potent antitumor activity. TioX may be involved in thiocoraline resistance or secretion. TioX belongs to vicinal oxygen chelate (VOC) superfamily that is composed of structurally related proteins with paired beta.alpha.beta.beta.beta motifs that provide a metal coordination environment with two or three open or readily accessible coordination sites to promote direct electrophilic participation of the metal ion in catalysis. VOC domain is found in a variety of structurally related metalloproteins, including the bleomycin resistance protein, glyoxalase I, and type I ring-cleaving dioxygenases. A bound metal ion is required for protein activities for the members of this superfamily. A variety of metal ions have been found in the catalytic centers of these proteins including Fe(II), Mn(II), Zn(II), Ni(II) and Mg(II). The protein superfamily contains members with or without domain swapping. The proteins of this family share three conserved metal binding amino acids with the type I extradiol dioxygenases, which shows no domain swapping.	2.26108e-32
NC_008595.1\|WP_011725002.1\|2754920_2755478_+\|peptidylprolyl-isomerase	gnl\|CDD\|223619	COG0545, FkpA, FKBP-type peptidyl-prolyl cis-trans isomerases 1 [Posttranslational modification, protein turnover, chaperones].	5.25617e-23
NC_008595.1\|WP_009976825.1\|2752491_2752812_+\|J-domain-containing-protein	gnl\|CDD\|365959	pfam00226, DnaJ, DnaJ domain. DnaJ domains (J-domains) are associated with hsp70 heat-shock system and it is thought that this domain mediates the interaction. DnaJ-domain is therefore part of a chaperone (protein folding) system. The T-antigens, although not in Prosite are confirmed as DnaJ containing domains from literature.	1.61446e-18
NC_008595.1\|WP_011724993.1\|2745374_2745686_+\|DUF732-domain-containing-protein	gnl\|CDD\|368380	pfam05305, DUF732, Protein of unknown function (DUF732). This family consists of several uncharacterized Mycobacterium tuberculosis and leprae proteins of unknown function.	7.22654e-12
NC_008595.1\|WP_011724991.1\|2744026_2744869_+\|AraC-family-transcriptional-regulator	gnl\|CDD\|378964	pfam12833, HTH_18, Helix-turn-helix domain.	2.55315e-14
NC_008595.1\|WP_011724986.1\|2736203_2737367_-\|acyl-CoA-dehydrogenase	gnl\|CDD\|173849	cd01160, LCAD, Long chain acyl-CoA dehydrogenase. LCAD is an acyl-CoA dehydrogenases (ACAD), which is found in the mitochondria of eukaryotes and in some prokaryotes. It catalyzes the alpha, beta dehydrogenation of the corresponding trans-enoyl-CoA by FAD, which becomes reduced. The reduced form of LCAD is reoxidized in the oxidative half-reaction by electron-transferring flavoprotein (ETF), from which the electrons are transferred to the mitochondrial respiratory chain coupled with ATP synthesis. LCAD acts as a homodimer.	2.8906e-141
NC_008595.1\|WP_023861579.1\|2743365_2743803_-\|hypothetical-protein	gnl\|CDD\|366161	pfam00553, CBM_2, Cellulose binding domain. Two tryptophan residues are involved in cellulose binding. Cellulose binding domain found in bacteria.	2.98001e-36
NC_008595.1\|WP_033722653.1\|2750763_2751207_+\|Hsp20-family-protein	gnl\|CDD\|365807	pfam00011, HSP20, Hsp20/alpha crystallin family. Not only do small heat-shock-proteins occur in eukaryotes and prokaryotes but they have also now been shown to occur in cyanobacterial phages as well as their bacterial hosts.	2.33587e-28
NC_008595.1\|WP_003876695.1\|2741775_2742429_-\|HD-domain-containing-protein	gnl\|CDD\|188314	TIGR03401, Uncharacterized_protein_YFL061W/YNL335W, HD domain protein, cyanamide hydratase family. Members of this protein family are known, so far, in the Ascomycota, a branch of the Fungi, and contain an HD domain (pfam01966), found typically in various metal-dependent phosphohydrolases. The only characterized member of this family, from the soil fungus Myrothecium verrucaria, is cyanamide hydratase (EC 4.2.1.69), a zinc-containing homohexamer that adds water to the fertilizer cyanamide (NCNH2), a nitrile compound, to produce urea (NH2-CO-NH2). Homologs are likely to be nitrile hydratases.	4.97586e-13
NC_008595.1\|WP_011724997.1\|2749369_2750599_-\|tRNA-4-thiouridine(8)-synthase-ThiI	gnl\|CDD\|234960	PRK01565, PRK01565, thiamine biosynthesis protein ThiI; Provisional.	1.4884e-178
NC_008595.1\|WP_009976816.1\|2746725_2748201_+\|biotin-carboxylase	gnl\|CDD\|180605	PRK06524, PRK06524, biotin carboxylase-like protein; Validated.	0

>NC_008595.1|WP_011724993.1|2745374_2745686_+|DUF732-domain-containing-protein
MIGAVLVGGAGIAAATPQDDAYLAQLRAAGLTWPPKTEEALIAEAHDVCYDLTWGWTPQQIADDLHARLDNKGVTLLDVGSLVNAAHNIYCPGNVCDAPSLCT
>NC_008595.1|WP_033711481.1|2744822_2745224_+|glyoxalase
MTASNPTVWLTLQAHNAPKLIDYYVETFGFVLAARYGDGETVDHAQLNWPEGSGGIMLGSHKPGAEWCREPGTAGGYVVTADPDALYRRVRQHNAEIVRPLAETDYGAREFTVRDPEGNLWSFGDYGGANPPN
>NC_008595.1|WP_011724991.1|2744026_2744869_+|AraC-family-transcriptional-regulator
MVGYRTLDVPEGVHRGMPSSMLTFIVSLDDGVEAADTATALPAARPTPLILGGLHLRASHVRQRRGQAGVQLAVHPLASRALFGLPSAELPVAEYDATAVLGRDIVDLHHRVAEAHRWPDVFALVAQYLIDARRRRDGATVRPEVLHAWHLLQRSRGLMPVTALADAVGVTTRHLATLFRREVGHSPKTVAMLMRFQHATGRIAESARRHGRVDLARVAADTGYSDQAHLSREFVRFAGVPPQRWLAEEFRNIQDGGHLLGSQWEHDCFESDRLVDTASP
>NC_008595.1|WP_023861579.1|2743365_2743803_-|hypothetical-protein
MAGLDNHVKRCRTALHGAVSAVIVAVVAVLGLAIAPVADAAAPMATLTVEHTWQTGFIARFAITNSSTVPLSDWKLEFDMPAGQSVLHTWNSTLTQSGTHYVLTPANWNRVIAPGGSATGGFRGVLTGTYSPPTNCVLNGQYRCT
>NC_008595.1|WP_011724989.1|2742474_2743185_-|SDR-family-oxidoreductase
MPSRRVLITGASRGIGRAVADRLAEGGHEPIGLARSAPEDFPGEFYEVDLADPYATAATLDKIVGHAAVHAVVNNVGFARFGRLGSIELDHLFDTYDLNVRAAVQVVQAALPGMLDAEWGRIVNVTSLTTLGTPERTPYAAAKAALEACTRIWAGELASAGITVNAVAPGPTETDMYRERSPVGSEREARFLQSIPLHRVARPREIAHAICFLLDEDAGYITGQILRVDGGGSIAA
>NC_008595.1|WP_003876695.1|2741775_2742429_-|HD-domain-containing-protein
MTTTSSIETIADIAIPDTALVREITEFIRDAEDDLLFHHSRRVFLFGALQGRRRGLQPDLELLYAGAMFHDLGLTERYRDSALRFEVDGANAAREFLLHRGVSKADADKVWLGIALHTTPGVPEFLDPEIALVTAGVETDVVGVGRDDLAPEALAAVIAAHPRPDFKTRILQAFNDGMKHRPHSTFGTMNADVLEHFDPTFARDNLVDLILNNGWPE
>NC_008595.1|WP_024636750.1|2738909_2739794_-|alpha/beta-fold-hydrolase
MFREPRVAYAATTVATHDGAQLHVRSYGSAFGQPIVLIHGFGCRIEYWNPQINALAAKYRVIAYDQRGLGRSTLGSDGVRPDVLGRDLAAVLDAVLAPGERAVLVGHSFGGITIMAWAQRFAAHAVSAVLLANTIAERFSATTMLLPFADRYRHIRRPLITALAGSTMTLPSIRWSRWPLQRMALSRYADRQAVDFVYEILADCRTDVRAVWGAGLSGLDVTAGLEKLTVPTTVVTGTEDRLTPPAVAHRIAEALQVRGSLHRFARFPRAGHCTNIEVPYAFNAEIEQLADATR
>NC_008595.1|WP_011724988.1|2738295_2738889_+|TetR/AcrR-family-transcriptional-regulator
MVMTNPRATNEDLTAKARIRNAALDLYAQYGEDRISLRDIASAAGVTLGLVQHHFKTKAGVRDAVDQLVVDYFAHALAQVPAEGSARHVAAARDEAVARMLRDNPPVVNYVRRAVLDPSEDRLHLLDALIELTRREITALRGSGVASTKRPESTQILGVLIRQMGELLLQPMVDAVWDRVAKPTDARKPRLRITVEN
>NC_008595.1|WP_011724987.1|2737369_2738188_-|CoA-transferase
MQPLIGVTVVSLAVNLPGPLAAARLAELGAAVTKVEPATGDPLAAAAPDWYARLIEHQNVLTLDLKDTGDRAKLDELLAGADLLITSMRPSALHRSGLARPQQRFPRLSLIEIVGHHGEHAETPGHDLNYQAAQGTLTPPHMPKVPIADVLGAERAVSSALAALLQAAKAGAGQRYRVVLEEAAARAGDAVRYGLMGEGAVLGGAYPGYGIYASADGYVALGAIEPHFFARTCQVFGADGSHESLGAAFAAKTTAELEDLARHMDIPLNEVR
>NC_008595.1|WP_011724986.1|2736203_2737367_-|acyl-CoA-dehydrogenase
MSELFPDYRPSWETDQHRELRKHAAEFFRKEATPNQERWAAQHAVDREFWNKAGDAGLLGLDLPEEYGGAGGDFAMNVVVQEELAYAYDQGFGFAVHSPIVAHYIWAYGSDEQRRRWLPKIISGEAVLAIAMTEPGTGSDLQSVKTTARRDGDFYVINGSKTFISNGTHCDLLVIVAKTDPSKGAAGVSLIVAETDENLAGFERGRVLAKMGQHAQDTRELFFSDMRVPVANLLGAQEGLGFYQLMEQLARERLIIATICAALAEVAVLEAIKYSREREAFGRPIGKFQHTKFVLAECKTEALAIKTMVDYAVGQYLDGKNDPATASMAKLFAAEKSDQIVDKCLQIFGGYGYMTEYPIANMYTASRVNRKYGRTSEIMKEIISRSL
>NC_008595.1|WP_009976816.1|2746725_2748201_+|biotin-carboxylase
MTHAGEPQPRRVLNGLSDIRAFFHTNSVPLYFISPTPFNLLGIDRWIRNFFYLTYFDSFEGIHSRVFVPRRRDRIDFDSMGDVCNHLLRDPETLEFIAGRGPGGKACFVMMDEETQALARQAGLQVMHPPVELRNRLGSKTVMTRLADEAGIPSVPHVMGRAGSYQELLTLAQDAGLGDDLVVSIPYGAAGSGTFFVRGQRDWDEHAGDLTAQQEFKVMKRIRNVEVCLEGAVTRHGTVIGPAMTSLVGYPELTPHRGAWCGNDIWREVLPPGQTHAARQMVGKLGDILSREGYRGYFEVDLLHDLDSDELYLGEVNPRLSGASPMTNLTTEAYADMPLFLFHLLEYMDVDYELDIEGINARWERGYGEDEVWGQVILAETSPDVELFTATPRTGVWRIDDDGRVSFSRTANDWATLLDGSEAFYMRVAAPGDLRSEGAQLGVLVTRGHLQTDDYRLTERCQRWVKGMKAKFASTPLAPATPIVSRLVARA
>NC_008595.1|WP_011724996.1|2748197_2749373_+|serine-hydrolase
MNAPAGISLDNWLSPPYARWSFQHVEDFVPTAVIARGTGPVAAIPAAPSELAEIRVAVTDGTASTVGAVMAGTATDGWAVAHRGAMIAEHYLEGMRRQTRHLLFSVSKSLVAAVVGALHGAGAIELDAPVTKYIPALANCGYAGATVRHLLDMRSGVAFSENYDDPAAQIHLLDQAVGWAPNHRPDAPATLRDFLLTLRQKSVHGGPFEYRSCETDVLGWICEVAADQPMPALMSELLWSRIGAQRDATIAVDPAGTGFFDGGISACLTDMIRFGSLFLREGVSLTGRRVLPEAWIADTLAGGPDSRRAFAASPDDNEMPGGMYRNQMWLPYPGDNVLLCLGMCGQMIYVNRAAEMVAAKVSTQPHSHEPHMLDTLSAFDAIAYRLAGRTD
>NC_008595.1|WP_011724997.1|2749369_2750599_-|tRNA-4-thiouridine(8)-synthase-ThiI
MHMQCCVLLKYGEMVLKGGNRRWFEQWLLTNLDDALSAWPPEHRPAVRRRGGVLVLFTSPELQDELVALARNLIGISLVQPVWRVPRSARAAETAAVELLRDHCTQDGAPTFAVRCHRRDKRFGLSSEQLAARIGARVRADLGWPVDLSHPELELTVEVDRREIFLGTRTHPGQGGLPVGSSGRAVVLLSGGFDSPVAAYRAMRRGLACDFLHCTGAPFTDASSTYKAYALVRQLTRFQPRSRLYVAAVGRAQRTLAASGAGEAQIVAQRRLYLRLACGLAERIGAQAVVTGDSLGQVASQTLPNLAATEQAATLPVLRPLLGFDKQEILAEARRIGTAEIAMLPDQDCCQLFLPRRVATHAAVDQLLPVEARAGVDTLVGNLLDRMQRFDFGPEAADVESAATASRVG
>NC_008595.1|WP_033722653.1|2750763_2751207_+|Hsp20-family-protein
MVNMLRFDPFFRDIDRLTQQLWGAVPWGTAAQPALVPMDAWRDGEKLVVEFDLPGVLPESLDVNVEHDVLTVRAERPAIDEDRNGVVSERPRGVFSRQVYLGHGLDTDNIHADYVDGVLRLTIPVAEAAKPRKIEVAAGKHQRAINA
>NC_008595.1|WP_011724999.1|2751266_2751647_-|helix-turn-helix-transcriptional-regulator
MRGDPTPRSARGVYGISVASELSGIPPQTLRHYERRGLLTPARSDGGTRRYSDDDLARLKRISQLVDQGVNLVGVARILDLESKNDQLKADYSALELLNAQLKTRQNSERAAAPRQGRGEARREAV
>NC_008595.1|WP_009976824.1|2751759_2752179_+|Hsp20-family-protein
MVLMRTDPFRDLDRWTQQVLGTAARPAVMPMDAWRDGDQFVVEFDLPGVNADSLDLDVERNVLTVRAERPDLDQNREMVSAERPRGVFSRQLFLGDNLDTDKIEANYHDGVLRLTIPVAEKAKPRRIEINHNHRTAINA
>NC_008595.1|WP_009976825.1|2752491_2752812_+|J-domain-containing-protein
MTNPYLVLGVSPTATQAEITRAYRRHLRAHHPDTSPPDSATESSERLSEILAAYALLRDPARRADYDREHRVHQRIRPAVTRVTRIEPADEQPPLRAGPVRWHRRY
>NC_008595.1|WP_011725000.1|2752864_2754271_-|acyltransferase
MPASYQQLHHLRRFSEHAARGLDMARLNIGVWDISGVCDVAAMTEAINAHLRRHDTYHSWFEHRTDGRIVRHTFDDPADIEFAALQRGEMTPTELRAHILATPNPLRWDCFTFGLVQHPDHFTFYMSADHLVIDGMSVGVIFLEIHLTYAALVSGGRPLPLPEPASYHDYCRRQHQHTEALTLQSPQVRAWIRFAEDNGGTLPSFPLPLGDPSVPCGSGVVVAPLMDESQTERFDATCTKAGARFSGGVFACAAFAEYELTGAETYCAITPYDHRSTPAEFVTPGWFASFIPVTFPVAGASFGDAVIAAQASFDSAIGLADVPFDRVLELSSFGGRISKPTGDVHMLSFADARGIPFSGQWDGLNAGIYGDGRSSDQVLMWVNRFDTETTLTVAFPQNPVARDSVERYIRAVRAMCLRVVEHGAAAVPNRRRVVAAVNASAARSTANAADRTDRRLQGAGFGANPVLR
>NC_008595.1|WP_011725002.1|2754920_2755478_+|peptidylprolyl-isomerase
MNSVRTFSVAAFAACFTAAAAMLASAGTAGAADSCPTAAPPSGGTPDWTLTGTTGSVAVTGSTDTAAPVVNVTAPFSVTQTQVHTLRAADGPAVPGTARVSVCYMGVNGRDGTVFDSSYQRGAPVDFPLGGVVPGFQKAIAGQKVGSTVAVAMTSADGYPDGQPSAGIRPGDTLVFAIKILGATT
>NC_008595.1|WP_011725003.1|2755525_2756287_-|SDR-family-oxidoreductase
MGLLDRKTAVITGANSGIGLATAERFLAEGVERVFITGRRQRELEDAARQLGPRATAVRGDVGAPRDLDRLYGEVAAAGAGLDIVMANAGTTRVARLGEITDDDLDTLLGTNVKGVVYTVQKALPLLNDGASIILTGSTTADRGRAGLSIYAATKAAVRSLARAWANELAHRNIRVNVLVAGSTATPGSDRLAAQTDPYVSVEEFRAGRIATIPLGRFADPVEIAHAAVFLASDLSSFCTGSTVTADGGFNQV

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Crispr_ID: NC_008595_6

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_008595_6

3515395-3515479

Orphan

Consensus_repeat	Method
CCTACCCCGCTTCGCGGCGCAGCGCGG	CRISPRCasFinder

1 spacers

The CRISPR arrays of NC_008595_6

>merge|NC_008595|6|3515395-3515479|CRISPRCasFinder
CCTACCCCGCTTCGCGGCGCAGCGCGGACGCGGCCAGGTCCATTTGTGTCGCGGCCGCCCTACCCCGCTTCGCGGCGTAGCGCGG

>NC_008595|6|6|3515395-3515479|CRISPRCasFinder
CCTACCCCGCTTCGCGGCGCAGCGCGG	ACGCGGCCAGGTCCATTTGTGTCGCGGCCGC
CCTACCCCGCTTCGCGGCGTAGCGCGG

Protein	Signature genes	Signature genes Name	Protein_function
NC_008595.1\|WP_003872542.1\|3512070_3513627_+\|MFS-transporter	unknown	unknown	gnl\|CDD\|129794
NC_008595.1\|WP_003872540.1\|3510648_3511248_-\|riboflavin-synthase	unknown	unknown	gnl\|CDD\|236455
NC_008595.1\|WP_011725433.1\|3522237_3523200_+\|alpha/beta-hydrolase	unknown	unknown	gnl\|CDD\|369561
NC_008595.1\|WP_011725424.1\|3506766_3507852_+\|cupin	unknown	unknown	gnl\|CDD\|369647
NC_008595.1\|WP_003872536.1\|3507884_3508223_+\|hemophore-related-protein	unknown	unknown	gnl\|CDD\|275322
NC_008595.1\|WP_011725434.1\|3523245_3524736_+\|NAD(P)/FAD-dependent-oxidoreductase	unknown	unknown	gnl\|CDD\|224983
NC_008595.1\|WP_031347726.1\|3516844_3517792_-\|methionyl-tRNA-formyltransferase	unknown	unknown	gnl\|CDD\|234567
NC_008595.1\|WP_011725427.1\|3513623_3514649_-\|bifunctional-diaminohydroxyphosphoribosylaminopyrimidine-deaminase/5-amino-6-(5-phosphoribosylamino)uracil-reductase-RibD	unknown	unknown	gnl\|CDD\|273015
NC_008595.1\|WP_011725432.1\|3521447_3522239_-\|lysoplasmalogenase	unknown	unknown	gnl\|CDD\|226237
NC_008595.1\|WP_011725430.1\|3517949_3518777_+\|class-I-SAM-dependent-methyltransferase	unknown	unknown	gnl\|CDD\|225136
NC_008595.1\|WP_003877628.1\|3511366_3512074_+\|LppX_LprAFG-lipoprotein	unknown	unknown	gnl\|CDD\|369238
NC_008595.1\|WP_011725426.1\|3509249_3510527_-\|bifunctional-3,4-dihydroxy-2-butanone-4-phosphate-synthase/GTP-cyclohydrolase-II	unknown	unknown	gnl\|CDD\|181774
NC_008595.1\|WP_011725425.1\|3508256_3508721_-\|PH-domain-containing-protein	unknown	unknown	gnl\|CDD\|371225
NC_008595.1\|WP_033710752.1\|3519395_3521363_-\|primosomal-protein-N'	unknown	unknown	gnl\|CDD\|237844
NC_008595.1\|WP_011725436.1\|3525774_3526758_+\|Lrp/AsnC-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|224439
NC_008595.1\|WP_085978450.1\|3514645_3515353_-\|ribulose-phosphate-3-epimerase	unknown	unknown	gnl\|CDD\|235515
NC_008595.1\|WP_011725437.1\|3526767_3527334_+\|pyridoxamine-5'-phosphate-oxidase-family-protein	unknown	unknown	gnl\|CDD\|334450
NC_008595.1\|WP_009977644.1\|3508717_3509200_-\|6,7-dimethyl-8-ribityllumazine-synthase	unknown	unknown	gnl\|CDD\|234606
NC_008595.1\|WP_003872548.1\|3518782_3519268_-\|MarR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|197670
NC_008595.1\|WP_011725435.1\|3524737_3525604_-\|LLM-class-flavin-dependent-oxidoreductase	unknown	unknown	gnl\|CDD\|274680

Protein	Function_ID	Function_description	E-value
NC_008595.1\|WP_003872542.1\|3512070_3513627_+\|MFS-transporter	gnl\|CDD\|129794	TIGR00711, Uncharacterized_MFS-type_transporter_YhcA, drug resistance transporter, EmrB/QacA subfamily. This subfamily of drug efflux proteins, a part of the major faciliator family, is predicted to have 14 potential membrane-spanning regions. Members with known activities include EmrB (multiple drug resistance efflux pump) in E. coli, FarB (antibacterial fatty acid resistance) in Neisseria gonorrhoeae, TcmA (tetracenomycin C resistance) in Streptomyces glaucescens, etc. In most cases, the efflux pump is described as having a second component encoded in the same operon, such as EmrA of E. coli. [Cellular processes, Toxin production and resistance, Transport and binding proteins, Other].	1.16841e-34
NC_008595.1\|WP_003872540.1\|3510648_3511248_-\|riboflavin-synthase	gnl\|CDD\|236455	PRK09289, PRK09289, riboflavin synthase.	3.62239e-107
NC_008595.1\|WP_011725433.1\|3522237_3523200_+\|alpha/beta-hydrolase	gnl\|CDD\|369561	pfam07859, Abhydrolase_3, alpha/beta hydrolase fold. This catalytic domain is found in a very wide range of enzymes.	3.78926e-88
NC_008595.1\|WP_011725424.1\|3506766_3507852_+\|cupin	gnl\|CDD\|369647	pfam08007, Cupin_4, Cupin superfamily protein. This family contains many hypothetical proteins that belong to the cupin superfamily.	6.20881e-73
NC_008595.1\|WP_003872536.1\|3507884_3508223_+\|hemophore-related-protein	gnl\|CDD\|275322	TIGR04529, hypothetical_protein, hemophore-related protein, Rv0203/Rv1174c family. Members of this family occur as paralogs in most Mycobacterium strains, including 2 in M. tuberculosis, 6 in M. avium, and 9 in M. smegmatis. Members have a cleaved N-terminal signal peptide and exactly two Cys residues in the mature protein, both at invariant positions. The best characterized member, Rv0203, is a hemophore, that is, a secreted polypeptide that binds heme and delivers it to a transport system for import. Hemophores are protein analogs of siderophores, natural products that chelate non-heme iron and deliver it to receptors for transport. The unrelated HasA family of hemophores has been described in Gram-negative bacteria such as Yersinia pestis and Pseudomonas aeruginosa. [Transport and binding proteins, Other].	9.08699e-11
NC_008595.1\|WP_011725434.1\|3523245_3524736_+\|NAD(P)/FAD-dependent-oxidoreductase	gnl\|CDD\|224983	COG2072, TrkA, Predicted flavoprotein involved in K+ transport [Inorganic ion transport and metabolism].	2.94716e-116
NC_008595.1\|WP_031347726.1\|3516844_3517792_-\|methionyl-tRNA-formyltransferase	gnl\|CDD\|234567	PRK00005, fmt, methionyl-tRNA formyltransferase; Reviewed.	1.22244e-159
NC_008595.1\|WP_011725427.1\|3513623_3514649_-\|bifunctional-diaminohydroxyphosphoribosylaminopyrimidine-deaminase/5-amino-6-(5-phosphoribosylamino)uracil-reductase-RibD	gnl\|CDD\|273015	TIGR00326, eubact_ribD, riboflavin biosynthesis protein RibD. This model describes the ribD protein as found in Escherichia coli. The N-terminal domain includes the conserved zinc-binding site region captured in the model dCMP_cyt_deam and shared by proteins such as cytosine deaminase, mammalian apolipoprotein B mRNA editing protein, blasticidin-S deaminase, and Bacillus subtilis competence protein comEB. The C-terminal domain is homologous to the full length of yeast HTP reductase, a protein required for riboflavin biosynthesis. A number of archaeal proteins believed related to riboflavin biosynthesis contain only this C-terminal domain and are not found as full-length matches to this model. [Biosynthesis of cofactors, prosthetic groups, and carriers, Riboflavin, FMN, and FAD].	2.96538e-106
NC_008595.1\|WP_011725432.1\|3521447_3522239_-\|lysoplasmalogenase	gnl\|CDD\|226237	COG3714, COG3714, Predicted membrane protein [Function unknown].	3.41217e-38
NC_008595.1\|WP_011725430.1\|3517949_3518777_+\|class-I-SAM-dependent-methyltransferase	gnl\|CDD\|225136	COG2226, UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis [Coenzyme metabolism].	8.31831e-24
NC_008595.1\|WP_003877628.1\|3511366_3512074_+\|LppX_LprAFG-lipoprotein	gnl\|CDD\|369238	pfam07161, LppX_LprAFG, LppX_LprAFG lipoprotein. This entry consists of several lipoproteins mainly from Mycobacterium species, collectively known as the LppX_ LprAFG family. Proteins in this entry include LprG, LppX, LprF and lprA.	7.28135e-89
NC_008595.1\|WP_011725426.1\|3509249_3510527_-\|bifunctional-3,4-dihydroxy-2-butanone-4-phosphate-synthase/GTP-cyclohydrolase-II	gnl\|CDD\|181774	PRK09311, PRK09311, bifunctional 3,4-dihydroxy-2-butanone-4-phosphate synthase/GTP cyclohydrolase II.	0
NC_008595.1\|WP_011725425.1\|3508256_3508721_-\|PH-domain-containing-protein	gnl\|CDD\|371225	pfam10756, bPH_6, Bacterial PH domain. This domain has a bacterial type PH domain structure. This domain was previously known as DUF2581. This family is conserved in the Actinomycetales. Although several members are annotated as RbiX homologs, RbiX being a putative regulator of riboflavin biosynthesis, the function could not be confirmed.	1.4462e-17
NC_008595.1\|WP_033710752.1\|3519395_3521363_-\|primosomal-protein-N'	gnl\|CDD\|237844	PRK14873, PRK14873, primosomal protein N'.	0
NC_008595.1\|WP_011725436.1\|3525774_3526758_+\|Lrp/AsnC-family-transcriptional-regulator	gnl\|CDD\|224439	COG1522, Lrp, Transcriptional regulators [Transcription].	7.00759e-19
NC_008595.1\|WP_085978450.1\|3514645_3515353_-\|ribulose-phosphate-3-epimerase	gnl\|CDD\|235515	PRK05581, PRK05581, ribulose-phosphate 3-epimerase; Validated.	7.84998e-136
NC_008595.1\|WP_011725437.1\|3526767_3527334_+\|pyridoxamine-5'-phosphate-oxidase-family-protein	gnl\|CDD\|334450	pfam01243, Putative_PNPOx, Pyridoxamine 5'-phosphate oxidase. Family of domains with putative PNPOx function. Family members were predicted to encode pyridoxamine 5'-phosphate oxidase, based on sequence similarity. However, there is no experimental data to validate the predicted activity and purified proteins, such as yeast YLR456W and its paralogs, do not possess this activity, nor do they bind to flavin mononucleotide (FMN). To date, the only time functional oxidase activity has been experimentally demonstrated is when the sequences contain both pfam01243 and pfam10590. Moreover, some of the family members that contain both domains have been shown to be involved in phenazine biosynthesis. While some molecular function has been experimentally validated for the proteins containing both domains, the role performed by each domain on its own is unknown.	1.17923e-08
NC_008595.1\|WP_009977644.1\|3508717_3509200_-\|6,7-dimethyl-8-ribityllumazine-synthase	gnl\|CDD\|234606	PRK00061, ribH, 6,7-dimethyl-8-ribityllumazine synthase; Provisional.	7.2232e-64
NC_008595.1\|WP_003872548.1\|3518782_3519268_-\|MarR-family-transcriptional-regulator	gnl\|CDD\|197670	smart00347, HTH_MARR, helix_turn_helix multiple antibiotic resistance protein.	1.26182e-20
NC_008595.1\|WP_011725435.1\|3524737_3525604_-\|LLM-class-flavin-dependent-oxidoreductase	gnl\|CDD\|274680	TIGR03619, F420_Rv2161c, probable F420-dependent oxidoreductase, Rv2161c family. Coenzyme F420 has a limited phylogenetic distribution, including methanogenic archaea, Mycobacterium tuberculosis and related species, Colwellia psychrerythraea 34H, Rhodopseudomonas palustris HaA2, and others. Partial phylogenetic profiling identifies protein subfamilies, within the larger family called luciferase-like monooxygenanases (pfam00296), that appear only in F420-positive genomes and are likely to be F420-dependent. This model describes a domain found in a distinctive subset of bacterial luciferase homologs, found only in F420-biosynthesizing members of the Actinobacteria. [Unknown function, Enzymes of unknown specificity].	6.19795e-35

>NC_008595.1|WP_085978450.1|3514645_3515353_-|ribulose-phosphate-3-epimerase
MALMPCNTGQPRGPLIAPSILSADFSRLADEAAAVTGADWLHVDVMDNHFVPNLTIGLPVVQSLLATTTIPMDCHLMIENPDRWAPPYAEAGAHNVTFHAEATDNPIGVARDIRAAGAKAGISVKPGTPLEPYLEILPQFDTLLIMSVEPGFGGQSFIPEVLGKVRTARKLIDAGELTILVEIDGGINADTIEQAAEAGVDCFVAGSAVYGADDPAAAVEALRRQALGASQHLRR
>NC_008595.1|WP_011725427.1|3513623_3514649_-|bifunctional-diaminohydroxyphosphoribosylaminopyrimidine-deaminase/5-amino-6-(5-phosphoribosylamino)uracil-reductase-RibD
MTASLGDRLDAAMRLAIEQSNQVKGNTYPNPPVGAVVLDGRGEVVGVGGTEPAGGDHAEILALRRAGDLAAGGTVVVTLEPCNHHGKTPPCVDALLEAGVSTVVYAVADPNPQAAGGAGRLQEAGVTVRSGLLADEVSGGPLREWLHKQRTGLPHLTWKYASSVDGRSAAADGSSRWISSEASRLDLHRRRAAADAIVVGTGTVLADDPALTARLPDGTLADRQPLRVVVGMREIPSEAKVLNDDSRTMVIRTHDPAEVLKAVSDRTDVLLEGGPTLAGAFVRAGLVNRILVYLAPTLLGGPVTAVDDVGVPTIAKALRWQFDGVDRVGPDLLLSLVPRSG
>NC_008595.1|WP_003872542.1|3512070_3513627_+|MFS-transporter
MTAQTGRRVAISAGSLAVLLGALDAYVVVTIMRDIMTDVHIPINQLQRITWIITMYLLGYIAAMPLLGRASDRFGRKLVLQVSLALFMVGSVVTALAGHWGDFHLLIGGRTIQGVASGALLPVTLALGADLWAQRNRAGVLGGIGAAQELGSVLGPLYGIFIVFLFHDWRYVFWINVPLTLIAMVMIQFSLPSHEKVEQPEKVDLVGGVLLAVALGLAVIGLYNPEPDGKQILPSYGLPLVLGAVVVGILFLLWERFARTRLIEPAGVHFRPFLAALGASLFAGAALMVTLVDVELFGQGVLGQDQTQAAGLLLWFLIALPIGAVLGGWIATRVGDRAMTFVGLLIAAYGYWLIHYWRQDVLSQKHNVLGLFSVPVLHADLLVAGVGLGLVIGPLTSAALRVVPSAQHGIASAAVVVARMTGMLIGVAALSAWGLYRFNQIVANLTAAIPPNASLLERIAAQGTMYLKAFAMMYGDIFAATVVICIAGALLGLLIGGRKEHAEEPEIVEPQAVSLGER
>NC_008595.1|WP_003877628.1|3511366_3512074_+|LppX_LprAFG-lipoprotein
MQTRRRLSAVFASLTLATALIAGCSSGSKQSGAPLPDPTSLVKQSADATKNVKSVHLVLSIQGKISGLPIKTLTGDLTTTPATAAKGNATITLGGSDIDANFVVVDGTLYATLTPNKWSDFGKASDIYDVSVLLNPDNGLGNALANFSNAKAEGRETINGQSTIRISGNVSADAVNKIMPQFNATQPVPSTVWVQETGDHQLVQANLQKSSGNSVQVTLSNWGEQVQVTKPPVSS
>NC_008595.1|WP_003872540.1|3510648_3511248_-|riboflavin-synthase
MFTGIVEELGEVTARDVLADAARLTIRGAVVTADAGHGDSIAVNGVCLTVAELLPDGRFSADVMGETLNRSNLGALQVGSRVNLERAAAVNSRLGGHIVQGHVDGTGRIVARTPSEHWEVVRIEVPPEVARYVVEKGSITVDGISLTVSGLGGEPRDWFEVSLIPTTRELTTLGGAPVGTQVNLEVDVIAKYVERLMSR
>NC_008595.1|WP_011725426.1|3509249_3510527_-|bifunctional-3,4-dihydroxy-2-butanone-4-phosphate-synthase/GTP-cyclohydrolase-II
MTRLDSVERAVADIAAGKAVIVIDDEDRENEGDLIFAAEKATPEMVAFMVRYTSGYLCVPLDGAICDRLGLLPMYAVNQDKHGTAYTVTVDARNGVGTGISASDRATTMRLLADPTSIAEDFTRPGHVVPLRAKDGGVLRRPGHTEAAVDLARMAGLQPAGAICEIVSQKDEGSMAQTDELRVFADEHDLAMITIADLIEWRRKHEKHIERIAEARIPTRHGEFRAIGYTSIYEEVEHVALVRGEIAGPNSDGDDVLVRVHSECLTGDVFGSRRCDCGPQLDAAMAMVAREGRGIVLYMRGHEGRGIGLMHKLQAYQLQDAGEDTVDANLKLGFPADARDYGIGAQILVDLGVRSMRLLTNNPAKRVGLDGYGLHIIERVPLPVRANAENIRYLMTKRDKMGHDLAGLDDFHESVHLPGEFGGAL
>NC_008595.1|WP_009977644.1|3508717_3509200_-|6,7-dimethyl-8-ribityllumazine-synthase
MSPAAGVPEMPALDASGVRLGIVASTWHSRICDALLAGARKVAADSGVENPTVVRVLGAIEIPVVAQELARNHDAVVALGVVIRGQTPHFEYVCDAVTQGITRVSLDASTPVANGVLTTDNEQQALDRAGLPDSAEDKGAQAAGAALSAALTLRELRARS
>NC_008595.1|WP_011725425.1|3508256_3508721_-|PH-domain-containing-protein
MTPPEPERWDVVLRPHRTPLFVYGAAVLIAAAHIVLGLLLKVGSTGVVFRTSDQVAIAVLGLVIAGVVLLFARPRLRIGPAGVSVRNLLGDKLIEWPDVVGVSFPVGHRWARIDLPDDEYIPVMAIQAVDKGRAVDAMDTVRSLLARYRPDLQG
>NC_008595.1|WP_003872536.1|3507884_3508223_+|hemophore-related-protein
MMKRSLAKLAVTVGGLALASTAGAGVASADPDYGPMINTTCSYDQAMRAVHAENPMAAQYLDQSPPNQQFLQQYLASSPDQRVNLLHAIEHNQGAQQALPIFQQMMTDCTRY
>NC_008595.1|WP_011725424.1|3506766_3507852_+|cupin
MAVESSLAWLLRPLGVDAFLNEIWATRHHHIDRCRPGYFDGLLPGPSAVDGLLEQVRPDPAAVRLVKDGEDRDPAGYRRGDGTLNAGGARDGLADGYTLVLNGLERYLRTVASLSHAIEVELNFPTRVNAYVTPPHSTGFVPHYDPHDVLVLQIEGCKTWRVSDEPPVPPQQIQSRKGVGADGPASRTDVCLRPGDVLYLPRGQVHSARTHSEPSVHLTVGLHAPTVLTLVTSALHALSLRDPRVHDRLPPRHLDDAQVRAGLGEAVRDAVRALDDDAVIADGLGAMEEVLVRRSRCPPVGSVRDTVGVDGHTLVRKHQPLYARVTRAGDGVAGRGRLSGPQGGAAGLAGLSSGYQASSST
>NC_008595.1|WP_031347726.1|3516844_3517792_-|methionyl-tRNA-formyltransferase
MRLVFAGTPEPALPALRRLLDSPRHEVIAVLTRPDAASGRRGKPEPSPVAREALDRGIPVLRPARPNSPEFVAELAQLAPDCCAVVAYGALLRDELLAVPPHGWINLHFSLLPAWRGAAPVQAAIAAGDTITGATTFRIEPALDSGPIYGVVTEAIRPTDTAGELLARLAVSGAELLSATLDGIADSTLTPRPQPAEGVSIAPKITVEQARVRWDLPAPVVERRIRAVTPNPGAWTVIGDLRIKLGPVRLGAASDLPAPPEPLPPGAIHVDRKSVWVGTASDPVRLDQIQPPGKKFMNAVDWARGARLDPAARAT
>NC_008595.1|WP_011725430.1|3517949_3518777_+|class-I-SAM-dependent-methyltransferase
MTLDTTTADASVAARHRTVWALGDYALMAEEVMAPLGPTLVEAAGIGPGVRVLDVAAGSGNITLPAAAAGASVVSTDLTPELLQRSRDRAAGMGLTIDYREANAQALPFGDGEFDAVVSAIGVQFAPDHQRAADELVRVCRPGGRIGLISWTPEGFFGRMLATIRPYRPSLSHPVPPAALWGRPGYVRALLGERIGEITTARGMLPVNRFGSAEDVHAYFKQHYGPTIEAYANIGHNRVLAAELDAQLVELAAQHLSDGTMGWEYLLVTAEKRSG
>NC_008595.1|WP_003872548.1|3518782_3519268_-|MarR-family-transcriptional-regulator
MAADHTTVDESLDAITDALLTASRLLMAISARSVGQVDETITIPQFRTLVILSNRGPVNLATLAGLLGVQPSATGRMVDRLVAAGLIDRLPHPTSRRELLAALTTRGRDVVHQVTAHRRAEIAAIVAKMPPAERHGLVRALTAFTAAGGEPDVHLDAEIDL
>NC_008595.1|WP_033710752.1|3519395_3521363_-|primosomal-protein-N'
MLSVPHLDREFDYLVSAEQSDDAQPGVRVRVRFHGRLVDGFLLERRHDTDHQGKLGWLDRVVSPEPVLTAEIRRLVDAVAARYAGTRPDVLRLAVPARHARVEREARAAAGIPMPAPVDPSGWEGYGRGAQFLAALAESRAARAVWQALPGEPWTDRFAEAAAQTVRAGRSVLAIVPDQRDLDALSHAVTTRIDAAGVVALSAGLGPAARYRRWLAALRGSARVVIGTRSAVFAPLSDLGLVMVWADADDSLAEPRAPYPHAREVAMLRAHQARCAALIGGYARTAEAQALVRSGWAHDIVAARPVVRARTPRVIALDDTGYADERDPAARTARIPSVALRAARSALQHGAPVLVQVPRRGYVPSLACARCRTIARCRHCTGPLSLAESPGEGGGGLVCRWCGRVDPTRRCARCGSDAVRAVVVGARRTAEELGRAFAGTTVITSSGDAVVPEVADGPALVVATPGAEPRARGDYGAALLLDTWALLGRQDLRAAEDALWRWMTAAALVRPRGDGGVVMVVAETSLPTVQSLIRWDPVGHAESELTARAEVGLPPSVHMAAVDGTPAAVNALLDEAGLTGGQTLHADLLGPVDLPPGARRPAGTPPGAPVTRMLVRVPRRDGLALAAALRRGVGVLSARQTHEPARVQIDPLHIG
>NC_008595.1|WP_011725432.1|3521447_3522239_-|lysoplasmalogenase
MEVPYAPRLVAGAWVVAGWVALAYGIYLTVLALRSPPGVELTGHWVLQPAFKASMALLLTLAAAGHGQVRERRWLMPALLLSAVGDWVLALPWWTLSFLVGLAAFLFAHMCFIGVLLPLVPLPSGASGPGRPSTPRIAAAVLMCLASIGLLVWFWPRLGPDKLTLPVTLYIVVLTAMVCAALLAKLPTIWTAVGAVCFAASDSMIAIGRFILGNEALAVPIWWAYAAAQILITAGFFFGREAAGDAAGEATGDAIGDAVEPVE
>NC_008595.1|WP_011725433.1|3522237_3523200_+|alpha/beta-hydrolase
MPRLDNPADEKPGIDPILQKVLDAVPFRLSTEDGIDAARQRFRDLPRRPLHPELRVEDRTIPGPQGAIAVRIYWPPIHSESRPAPVVLYFHGGGFVIGDLDTHDGTARQHAVGAGAIVVSVDYRLAPEHPYPAAVEDAWAATLWAAENAAGLHGDPGRIAVAGDSAGGTLAAVTAQRARDRGGPPVRFQLLWYPSTMWDASLPSFAENATAPILDVKAVAEFSRWYAGDVDLSDPPADMAPGRATDLSNLPPAYIGVAGYDPLRDDGIRYGERLAAAGVAAQVHNAETLVHGYLGYAGVVPAATAAMERGLVALRTALQG
>NC_008595.1|WP_011725434.1|3523245_3524736_+|NAD(P)/FAD-dependent-oxidoreductase
MSSPAVPDHHTLIIGAGFSGIGAAIKLDKAGLPDYRVIEAGDGVGGTWHWNTYPGIAVDIPSFSYQFSFEQSRHWSRTYAPGRELKAYAEHCADKYGIRSRIRFNTKVLAAEFDDEQRLWRVQTDPGGEVTARFLISACGVLTVPNLPDIDGVDSFAGITMHTARWDHGQDLRGKRVAVIGTGASAVQVIPEIAPIVSSLTVFQRTPIWCFPKLDVPLPAPARWAMRFPGGKALQRLLSQAYVELTFPISAHYFTVIPLAKRMAALGRAYLRRQVRDPAVREQLTPRYAVGCKRPGFHNGYLATFNRDNVRLVTEPIDKITPDAVATTDGETHEIDVLILATGFKVMDPDSVPTFAVTGSGGRSLSRFWDEHRLQAYEGVTVPGFPNLFTVFGPYGYVGSSYFALIEAQTHHIVRCLKRAQRLGATRVEVSEEANDRYFAEMMRRRHRQIFWQDSCRLANSYYFDKNGDVPLRPGTTPEVYWRSRRFDLDDYRFTG
>NC_008595.1|WP_011725435.1|3524737_3525604_-|LLM-class-flavin-dependent-oxidoreductase
MKLGIGLPNHIADVPGPAVAQWSRRGEELGFESVATIDRLFSSGVDSLIALATAAGATNELTLVTNVLLAPMYPVIPLAKQLVSLARVSGGRLTVGLGVGNRSDEYAGTGADFHRRGRALDAQVERLRSLWAGEPLADGTALCGAPVRIPLLFGGRSAATVRRVVTTGDGWAAGAVRLYDEQADVAARIRSGWQDAGRPARPYLQASVNFALGPAETVAAGRDHLARYYAFAPGYAQVNVADMVCSAADARDTVRRYRDLGFDRLLFHPTSASVEQLDYLADAILGCL
>NC_008595.1|WP_011725436.1|3525774_3526758_+|Lrp/AsnC-family-transcriptional-regulator
MEALDGHILHALQLSPRAPFRRIAEVVGAGEQTVARRYRALRRDGVLRAVGVVNPRVYGECQWIVRVRAKPDDLLRLAEALVRRADVTHANVLSGGTELVCVVRAPLDDTEAGLLHRLPRTSTVLDMRVDLVINVFGAPMHAHWTGHGHALDGHQVAALRPAHCAHPDRPVGPTPEDQPLLDALAEDGRISDSALAGLTGWSPARVKRRMVALQGSGTLSFDLDVLPERLGFMLHAIIWISVVPQHLTSVAEQIVRHDEVASVATVSGPANLMVVVICRDPEHFYRYLAERLASVDHIQAYDVSVRSKRLKQVGSLIAHGRLVRAAR
>NC_008595.1|WP_011725437.1|3526767_3527334_+|pyridoxamine-5'-phosphate-oxidase-family-protein
MAKEFGSIDESLRDFIREQAVFFVATAPSEGGRINLSPKGYCDTFAVLDERTVAYLDLFGSGVETIAHLRDNGRITVMFCSFTRNSRILRLFGTGRVIRPDDAEFADLITHFGDRHAGIRAIIVVNVERIADACGFAVPYYELVDERPVLNAYHHKASDEAYTRLINRNRRSIDGLPALDSDHPGPPR

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Crispr_ID: NC_008595_7

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_008595_7

3625433-3625509

Orphan

Consensus_repeat	Method
CAGTCGGCGTCATGGGCGGTCATC	CRISPRCasFinder

1 spacers

The CRISPR arrays of NC_008595_7

>merge|NC_008595|7|3625433-3625509|CRISPRCasFinder
CAGTCGGCGTCATGGGCGGTCATCTGCGCCGCTCCTCCTCATCGCTTCGCTCTGCATCGGCGTCATGGGCGGTCATC

>NC_008595|7|7|3625433-3625509|CRISPRCasFinder
CAGTCGGCGTCATGGGCGGTCATC	TGCGCCGCTCCTCCTCATCGCTTCGCTCT
GCATCGGCGTCATGGGCGGTCATC

Protein	Signature genes	Signature genes Name	Protein_function
NC_008595.1\|WP_031347718.1\|3627479_3627983_+\|DUF2617-family-protein	unknown	unknown	gnl\|CDD\|378512
NC_008595.1\|WP_011725488.1\|3615703_3617530_-\|protein-translocase-subunit-SecD	unknown	unknown	gnl\|CDD\|235615
NC_008595.1\|WP_011725485.1\|3612165_3612708_-\|adenine-phosphoribosyltransferase	unknown	unknown	gnl\|CDD\|235028
NC_008595.1\|WP_011725491.1\|3626848_3627460_+\|DUF4178-domain-containing-protein	unknown	unknown	gnl\|CDD\|379368
NC_008595.1\|WP_011725487.1\|3614393_3615701_-\|protein-translocase-subunit-SecF	unknown	unknown	gnl\|CDD\|237275
NC_008595.1\|WP_009977768.1\|3618143_3619493_+\|4-aminobutyrate--2-oxoglutarate-transaminase	unknown	unknown	gnl\|CDD\|235685
NC_008595.1\|WP_011725486.1\|3612715_3614389_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|173866
NC_008595.1\|WP_011725496.1\|3631369_3631966_-\|pyridoxal-5'-phosphate-synthase-glutaminase-subunit-PdxT	unknown	unknown	gnl\|CDD\|237411
NC_008595.1\|WP_011725495.1\|3628907_3630479_+\|polyamine-aminopropyltransferase	unknown	unknown	gnl\|CDD\|235139
NC_008595.1\|WP_003878553.1\|3632808_3633720_-\|pyridoxal-5'-phosphate-synthase-lyase-subunit-PdxS	unknown	unknown	gnl\|CDD\|179769
NC_008595.1\|WP_011725493.1\|3627979_3628411_+\|DUF4247-domain-containing-protein	unknown	unknown	gnl\|CDD\|379437
NC_008595.1\|WP_003875361.1\|3631962_3632799_-\|acyl-CoA-thioesterase-II	unknown	unknown	gnl\|CDD\|272951
NC_008595.1\|WP_011725490.1\|3619655_3623177_+\|carboxylic-acid-reductase	unknown	unknown	gnl\|CDD\|341287
NC_008595.1\|WP_003872683.1\|3623242_3623920_-\|hypothetical-protein	unknown	unknown	unknown
NC_008595.1\|WP_011725483.1\|3608099_3609752_+\|protein-kinase	unknown	unknown	gnl\|CDD\|270916
NC_008595.1\|WP_011725494.1\|3628455_3628911_+\|DUF350-domain-containing-protein	unknown	unknown	gnl\|CDD\|377187
NC_008595.1\|WP_003877574.1\|3626100_3626667_-\|crossover-junction-endodeoxyribonuclease-RuvC	unknown	unknown	gnl\|CDD\|234587
NC_008595.1\|WP_003872680.1\|3617653_3617980_-\|preprotein-translocase-subunit-YajC	unknown	unknown	gnl\|CDD\|235636
NC_008595.1\|WP_009977789.1\|3630489_3631242_-\|YebC/PmpR-family-DNA-binding-transcriptional-regulator	unknown	unknown	gnl\|CDD\|234640
NC_008595.1\|WP_031345041.1\|3609755_3612122_-\|RelA/SpoT-family-protein	unknown	unknown	gnl\|CDD\|213552

Protein	Function_ID	Function_description	E-value
NC_008595.1\|WP_031347718.1\|3627479_3627983_+\|DUF2617-family-protein	gnl\|CDD\|378512	pfam10936, DUF2617, Protein of unknown function DUF2617. This bacterial family of proteins has no known function.	3.1134e-56
NC_008595.1\|WP_011725488.1\|3615703_3617530_-\|protein-translocase-subunit-SecD	gnl\|CDD\|235615	PRK05812, secD, preprotein translocase subunit SecD; Reviewed.	1.97837e-126
NC_008595.1\|WP_011725485.1\|3612165_3612708_-\|adenine-phosphoribosyltransferase	gnl\|CDD\|235028	PRK02304, PRK02304, adenine phosphoribosyltransferase; Provisional.	3.78517e-74
NC_008595.1\|WP_011725491.1\|3626848_3627460_+\|DUF4178-domain-containing-protein	gnl\|CDD\|379368	pfam13785, DUF4178, Domain of unknown function (DUF4178).	5.89955e-37
NC_008595.1\|WP_011725487.1\|3614393_3615701_-\|protein-translocase-subunit-SecF	gnl\|CDD\|237275	PRK13022, secF, protein translocase subunit SecF.	2.72371e-115
NC_008595.1\|WP_009977768.1\|3618143_3619493_+\|4-aminobutyrate--2-oxoglutarate-transaminase	gnl\|CDD\|235685	PRK06058, PRK06058, 4-aminobutyrate--2-oxoglutarate transaminase.	0
NC_008595.1\|WP_011725486.1\|3612715_3614389_-\|hypothetical-protein	gnl\|CDD\|173866	cd08501, PBP2_Lpqw, The substrate-binding domain of mycobacterial lipoprotein Lpqw contains type 2 periplasmic binding fold. LpqW is one of key players in synthesis and transport of the unique components of the mycobacterial cell wall which is a complex structure rich in two related lipoglycans, the phosphatidylinositol mannosides (PIMs) and lipoarabinomannans (LAMs). Lpqw is a highly conserved lipoprotein that transport intermediates from a pathway for mature PIMs production into a pathway for LAMs biosynthesis, thus controlling the relative abundance of these two essential components of cell wall. LpqW is thought to have been adapted by the cell-wall biosynthesis machinery of mycobacteria and other closely related pathogens, evolving to play an important role in PIMs/LAMs biosynthesis. Most of periplasmic binding proteins are comprised of only two globular subdomains corresponding to domains I and III of the LpqW protein. The structural topology of these domains is most similar to that of the type 2 periplasmic binding proteins (PBP2), which are responsible for the uptake of a variety of substrates such as phosphate, sulfate, polysaccharides, lysine/arginine/ornithine, and histidine. The PBP2 bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap. After binding their specific ligand with high affinity, they can interact with a cognate membrane transport complex comprised of two integral membrane domains and two cytoplasmically located ATPase domains. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis. Besides transport proteins, the PBP2 superfamily includes the ligand-binding domains from ionotropic glutamate receptors, LysR-type transcriptional regulators, and unorthodox sensor proteins involved in signal transduction.	1.99853e-74
NC_008595.1\|WP_011725496.1\|3631369_3631966_-\|pyridoxal-5'-phosphate-synthase-glutaminase-subunit-PdxT	gnl\|CDD\|237411	PRK13525, PRK13525, pyridoxal 5'-phosphate synthase glutaminase subunit PdxT.	5.52647e-110
NC_008595.1\|WP_011725495.1\|3628907_3630479_+\|polyamine-aminopropyltransferase	gnl\|CDD\|235139	PRK03612, PRK03612, polyamine aminopropyltransferase.	0
NC_008595.1\|WP_003878553.1\|3632808_3633720_-\|pyridoxal-5'-phosphate-synthase-lyase-subunit-PdxS	gnl\|CDD\|179769	PRK04180, PRK04180, pyridoxal 5'-phosphate synthase lyase subunit PdxS.	0
NC_008595.1\|WP_011725493.1\|3627979_3628411_+\|DUF4247-domain-containing-protein	gnl\|CDD\|379437	pfam14042, DUF4247, Domain of unknown function (DUF4247). This family of proteins is functionally uncharacterized. This family of proteins is found in bacteria. Proteins in this family are typically between 143 and 271 amino acids in length.	5.85353e-32
NC_008595.1\|WP_003875361.1\|3631962_3632799_-\|acyl-CoA-thioesterase-II	gnl\|CDD\|272951	TIGR00189, Peroxisomal_acyl-coenzyme_A_thioester_hydrolase_1, acyl-CoA thioesterase II. Function: hydrolyzes a broad range of acyl-CoA thioesters. Physiological function is not known. Subunit: homotetramer. [Fatty acid and phospholipid metabolism, Biosynthesis].	2.17607e-125
NC_008595.1\|WP_011725490.1\|3619655_3623177_+\|carboxylic-acid-reductase	gnl\|CDD\|341287	cd17632, AFD_CAR-like, adenylation domain of carboxylic acid reductase (CAR). This family contains the adenylation domain of carboxylic acid reductase enzymes (CARs), and performs an equivalent function to that of the ANL superfamily of adenylating enzymes. It takes a carboxylic acid substrate and ATP, and produces an AMP-acyl phosphoester intermediate, releasing pyrophosphate. Kinetic analysis using various substrates shows that this enzyme has a broad but similar substrate specificity, preferring electron-rich acids. This suggests that attack by the carboxylate on the alpha-phosphate of adenosine triphosphate (ATP) is the step that determines the substrate specificity and reaction kinetics. CAR is an important enzyme for use as a biocatalyst providing regiospecific route to aldehydes from their respective carboxylic acids.	0
NC_008595.1\|WP_011725483.1\|3608099_3609752_+\|protein-kinase	gnl\|CDD\|270916	cd14014, STKc_PknB_like, Catalytic domain of bacterial Serine/Threonine kinases, PknB and similar proteins. STKs catalyze the transfer of the gamma-phosphoryl group from ATP to serine/threonine residues on protein substrates. This subfamily includes many bacterial eukaryotic-type STKs including Staphylococcus aureus PknB (also called PrkC or Stk1), Bacillus subtilis PrkC, and Mycobacterium tuberculosis Pkn proteins (PknB, PknD, PknE, PknF, PknL, and PknH), among others. S. aureus PknB is the only eukaryotic-type STK present in this species, although many microorganisms encode for several such proteins. It is important for the survival and pathogenesis of S. aureus as it is involved in the regulation of purine and pyrimidine biosynthesis, cell wall metabolism, autolysis, virulence, and antibiotic resistance. M. tuberculosis PknB is essential for growth and it acts on diverse substrates including proteins involved in peptidoglycan synthesis, cell division, transcription, stress responses, and metabolic regulation. B. subtilis PrkC is located at the inner membrane of endospores and functions to trigger spore germination. Bacterial STKs in this subfamily show varied domain architectures. The well-characterized members such as S. aureus and M. tuberculosis PknB, and B. subtilis PrkC, contain an N-terminal cytosolic kinase domain, a transmembrane (TM) segment, and mutliple C-terminal extracellular PASTA domains. The PknB subfamily is part of a larger superfamily that includes the catalytic domains of other protein STKs, protein tyrosine kinases, RIO kinases, aminoglycoside phosphotransferase, choline kinase, and phosphoinositide 3-kinase.	2.06317e-116
NC_008595.1\|WP_011725494.1\|3628455_3628911_+\|DUF350-domain-containing-protein	gnl\|CDD\|377187	pfam03994, DUF350, Domain of Unknown Function (DUF350). This domain occurs in a small set of of bacterial proteins. It has two transmembrane regions, and often occurs as tandem repeats. The are no conserved catalytic residues.	8.08014e-07
NC_008595.1\|WP_003877574.1\|3626100_3626667_-\|crossover-junction-endodeoxyribonuclease-RuvC	gnl\|CDD\|234587	PRK00039, ruvC, Holliday junction resolvase; Reviewed.	1.22003e-76
NC_008595.1\|WP_003872680.1\|3617653_3617980_-\|preprotein-translocase-subunit-YajC	gnl\|CDD\|235636	PRK05886, yajC, preprotein translocase subunit YajC; Validated.	1.1403e-61
NC_008595.1\|WP_009977789.1\|3630489_3631242_-\|YebC/PmpR-family-DNA-binding-transcriptional-regulator	gnl\|CDD\|234640	PRK00110, PRK00110, YebC/PmpR family DNA-binding transcriptional regulator.	2.16409e-148
NC_008595.1\|WP_031345041.1\|3609755_3612122_-\|RelA/SpoT-family-protein	gnl\|CDD\|213552	TIGR00691, PppGpp_synthetase., (p)ppGpp synthetase, RelA/SpoT family. The functions of E. coli RelA and SpoT differ somewhat. RelA (EC 2.7.6.5) produces pppGpp (or ppGpp) from ATP and GTP (or GDP). SpoT (EC 3.1.7.2) degrades ppGpp, but may also act as a secondary ppGpp synthetase. The two proteins are strongly similar. In many species, a single homolog to SpoT and RelA appears reponsible for both ppGpp synthesis and ppGpp degradation. (p)ppGpp is a regulatory metabolite of the stringent response, but appears also to be involved in antibiotic biosynthesis in some species. [Cellular processes, Adaptations to atypical conditions].	0

>NC_008595.1|WP_003872683.1|3623242_3623920_-|hypothetical-protein
MKYAEDGHTRGLSMPRSRGAVSGLLLVILGAWGALIPFVGPHFNFAYTPDRDWAWSSARGWLEVAPGAATALGGLLLIVAGNRVAAMLGGWLAVLAGAWFVVGGQLAPLLGIGSAGDPIAATERKRALLEVTYFSGLGALIIFVGGVVLARTSARLARDVQPLASDAPAAPAVEPYRDPAYDPADVSSGALTKPRTSADPEPKRGWRKNRAGGNAAYLRWPHPQQ
>NC_008595.1|WP_011725490.1|3619655_3623177_+|carboxylic-acid-reductase
MSTATHDERLDRRVHELIATDPQFAAAQPDPAITAALEQPGLRLPQIIRTVLDGYADRPALGQRVVEFVTDAKTGRTSAQLLPRFETITYGEVAQRVSALGRALSDDAVHPGDRVCVLGFNSVDYATIDMALGAIGAVSVPLQTSAAISSLQPIVAETEPTLIASSVNQLSDAVQLITGAEQAPTRLVVFDYHPQVDDQREAVQDAAARLSGTGVAVQTLAELLERGKDLPAVAEPPADEDSLALLIYTSGSTGAPKGAMYPQSNVGKMWRRGSKNWFGESAASITLNFMPMSHVMGRSILYGTLGNGGTAYFAARSDLSTLLEDLELVRPTELNFVPRIWETLYGEFQRQVERRLSEAGDAGERRAVEAEVLAEQRQYLLGGRFTFAMTGSAPISPELRNWVESLLEMHLMDGYGSTEAGMVLFDGEIQRPPVVDYKLVDVPDLGYFSTDRPHPRGELLLRTENMFPGYYKRAETTAGVFDEDGYYRTGDVFAEIAPDRLVYVDRRNNVLKLAQGEFVTLAKLEAVFGNSPLIRQIYVYGNSAQPYLLAVVVPTEEALASGDPETLKPKIADSLQQVAKEAGLQSYEVPRDFIIETTPFSLENGLLTGIRKLAWPKLKQHYGERLEQMYADLAAGQADELAELRRNGAQAPVLQTVSRAAGAMLGSAASDLSPDAHFTDLGGDSLSALTFGNLLREIFDVDVPVGVIVSPANDLAAIASYIEAERQGSKRPTFASVHGRDATVVRAADLTLDKFLDADTLASAPNLPKPATEVRTVLLTGATGFLGRYLALEWLERMDMVDGKVIALVRARSDEEARARLDKTFDSGDPKLLAHYQQLAADHLEVIAGDKGEANLGLRQDVWQRLADTVDVIVDPAALVNHVLPYSELFGPNALGTAELIRLALTSKQKPYTYVSTIGVGDQIEPGKFVENADIRQMSATRAINDSYANGYGNSKWAGEVLLREAHDLCGLPVAVFRCDMILADTTYAGQLNLPDMFTRLMLSLVATGIAPGSFYELDADGNRQRAHYDGLPVEFIAAAISTLGSQITDSDTGFQTYHVMNPYDDGIGLDEYVDWLVDAGYSIERIADYSEWLRRFETSLRALPDRQRQYSLLPLLHNYRTPEKPINGSIAPTDVFRAAVQEAKIGPDKDIPHVSPPVIVKYITDLQLLGLL
>NC_008595.1|WP_009977768.1|3618143_3619493_+|4-aminobutyrate--2-oxoglutarate-transaminase
MARLEQTRRLVTEIPGPASLELSKRRAAAVSHAVNVSVPVFVARAGGGIVEDVDGNRLIDLGSGIAVTTIGNSAPRVVDAVRAQVAEFTHTCFMVTPYESYVAVAETLNRITPGAGEKRSVLFNSGAEAVENAVKVARAYTRKPAVVAFDHAYHGRTNLAMALTAKSMPYKGGFGPFAPEIYRAPLSYPYRDGLLDKELATDGEKAAARAINIIDGQIGADSLAAVIIEPIQGEGGFIVPAEGFLPTLLDWCRRNDVLFIADEVQTGFARSGAMFACEHEGPNGLEPDLICTAKAIADGLPLSAVTGRAQIMDAPHVGGLGGTFGGNPLACAAALATIETIESDGLIERARQLERLITEPLLRLQARDDRIGDVRGRGAMIAIELVKSGTAEPDKDLTQRLSVAAHAAGVIVLTCGMFGNIIRLLPPLTISDELLAEGIDILGGLLADL
>NC_008595.1|WP_003872680.1|3617653_3617980_-|preprotein-translocase-subunit-YajC
MESLILFLPFLLIMGGFMYFASRRQRRAMQATIELHESLRPGDRVHTTSGLQATVVGLTDDTVDLEIAPGVVTTWMKLAIRDRIVPDDEDDLVDGDDSAGEGSVSKDS
>NC_008595.1|WP_011725488.1|3615703_3617530_-|protein-translocase-subunit-SecD
MASSSVPVHPARYLSVFLLLLVGVYLLVFLTGDKRAAPKLGIDLQGGTRVTLTARTPDGSAPSREALAQAQQIISARVNGLGVSGSEVVVDGDNLIITVPGNDGNEARNLGQTARLYIRPVLNSMPAQSGEPKPAPRQPAQPAPGQPAPGQPAPGQPAPGQPAPGQPAPGQPAPAPAQPGAAPAQPRPYPQDPPPSPSPAPAPAPAPGPAPAPAPAPAPGEAPPGEQPAPPDPRKDLAERIAEEKKWRQSTRQGIQFLALQFQATRCDKDDILAGNDDPAQPLITCSTDHKVAYLLGPSIISGDQIKDASASQNQRGIGFVVDLQFKPAAANTWADFTAAHIGTQTAFTLDSQVVSAPMIQEAIPGGRTQISGGDPPFTAATAKQLANVLKYGSLPLSFQSSEAQTVSATLGLTSLRAGLIAGAIGLLLVLLYSLLYYRVLGLLTALSLAASGAMVFAILILLGRYINYTLDLAGIAGLIIGIGTTADSFVVFFERIKDEIREGRTFRSAVPRGWTRARKTIVSGNAVTFLAAAVLYFLAIGQVKGFAFTLGLTTILDLVVVFLVTWPLVYLASKSPTLAKPAYNGLGAVQQVARERRAAAHVSTGQG
>NC_008595.1|WP_011725487.1|3614393_3615701_-|protein-translocase-subunit-SecF
MTSSKASKAAKGATEITETSSGASELTDSDAAAAGLPRHSFLSRLYTGTGAFEVVGRRRLWFGISGAIVAVAILSIALRGFTFGIDFNGGTTVSMPAAGTHGTVHTAQVQEVFRKTLGTDPESVVVVGNGAAATVQIRSETLTNDQTTKLRNALFDAFGPKGADGKPSKQAISDSAVSETWGDQITDKALIALVVFLALVGLYITVRYERYMTLAAIAAMFFDLTVTAGVYSLVGFEVTPATVIGLLTILGFSLYDTVIVFDKVEENTRDFQHTNRRTFAEQANLAINQTFMRSINTSLIGVLPVLALMVVAVWLLGVGTLKDLALVQLVGILVGTYSSIFVATPLLVTLRERTELVRTHTRRVLKRRAGGARASAESTADDAAETPAGSGDEATEAERESPSSRAAPSKPAPGARPVRPTGARRPTGKRNVGRR
>NC_008595.1|WP_011725486.1|3612715_3614389_-|hypothetical-protein
MAIRIGRRGLTGWVGIGVAVLVVAGVTLAGCAGSAAAEIDYVVDGPLSSYNPNTVVGAASAGAQAFARTLVGFSYHGPDGQTVPDRDFGTVSVVGGTPLVLDYQIADNAVYSDGKPVTCDDIVLAWAAQSGRYPEFNAATQAGYLDIANVECMPGQKKARVSFIPDRGIVDYNQLFTATTLMPSHVIADQLNVDVTAALLSHNAPLVAQIARLWNTIWDLKPGLKGEEILKRFPSSGPYKLQAVLDGGAVVLVANDRWWGPKAITKRITVWPQGPDIQDRVNNRSVDVVDVAAGSSGTLATPDNYDRSDAPSDGIEQLIFAPQGPLSAPKARRAFALCTPRDVLAKDAGTPIANSRLDPAVDDAVSAGDGAAEAAPFGKADPVAAREALGGAPLAVRIGYQGPNARLAVNVGVITKACAPAGITVSGVTLDSAGPQALRDGKIDALLASTGGATGSGSSGSSAMDAYALHTGNGNNLSGYSNPQVDNAIGALAVSADPAERVRLLAETAPVLWGDLPTLPLYRQQRTLLISKKMYAVSKNPTRWGAGWNMDRWALVQ
>NC_008595.1|WP_011725485.1|3612165_3612708_-|adenine-phosphoribosyltransferase
MTDAGEATPVAELIASLTRQVPDFPKPGIQFKDLTPLFADATAMTAVTGALARHASGADLVAGIDSRGFLVAAAVADRLHTGVLAIRKGGKLPPPVHAERYDLEYGSATLEIPADGIDLRGRRIVIIDDVLATGGTLAAAARLLRRTGATVTAAAVVFELGALGGRAALAPLPVHRLTCQ
>NC_008595.1|WP_031345041.1|3609755_3612122_-|RelA/SpoT-family-protein
MAEENSAAQALDAPAESPPNPVIETPEPPTESLKTSSSASRRVRARLARRMTAQRSTLNPVLEPLVAMHREIYPKANVQLLQRAFEVADQRHASQLRHSGDPYITHPLAVATILAELGMDSTTLVAALLHDTVEDTGYTLAQLSEEFGEEVGHLVDGVTKLDRVVLGSAAEGETIRKMITAMARDPRVLVIKVADRLHNMRTMRFLPPEKQARKARETLEVIAPLAHRLGMASVKWELEDLSFAILHPKKYDEIVRLVAGRAPSRDTYLAKVRAEIINTLNASKIKATVEGRPKHYWSIYQKMIVKGRDFDDIHDLVGIRILCDEIRDCYAAVGVVHSLWQPMAGRFKDYIAQPRYGVYQSLHTTVVGPEGKPLEVQIRTRDMHRTAEYGIAAHWRYKEAKGRNGVPHPHAAAEIDDMAWMRQLLDWQREAADPGEFLESLRYDLAVQEIFVFTPKGDVITLPTGSTPIDFAYAVHTEVGHRCIGARVNGRLVALERKLENGEVVEVFTSKAANAGPSRDWQQFVVSPRAKAKIRQWFAKERREEALEAGKDAMAREVRRGGLPLQRLVNAESMSAVARELHYADVSALYTAIGEGHVSARHVVQRLLAELGGIDQAEEDLAERSTPTTMLRRPRSSDDVGVSVPGAPGVLTKLAKCCTPVPGDQIMGFVTRGGGVSVHRTDCTNAASLQQQSERIIEVHWAPSPSSVFLVAIQVEALDRHRLLSDVTRVLADEKVNILSASVTTSGDRVAISRFTFEMGDPKHLGHLLNVVRNVEGVYDVYRVTSAA
>NC_008595.1|WP_011725483.1|3608099_3609752_+|protein-kinase
MTLDPDSFGHYRILELLGRGGMGRVYRAYDATTDRVVALKVLPPHLAEDQDFQQRFRREARIAAGLNDPHVVPIHGYGEIDGQLYVDMRLIEGRDLAHYITENGGRLSPQRAVAVIEQVAAALDSAHRAGLIHRDVKPMNVLVTTARDFVYLIDFGLARAQADTALTQTGATMGTVAYMAPERFTGTTDHRADVYSLACVLHECLTGKRPFAGDSLEEQLNAHLNTAPPRPSATAPEVPAAFDAVIARGMAKDPERRYQSVTELAEAARAALAPGAVEKPSAPTPQPRAARRVRAAVVGASALTLAVVAAVVVAMVTHGHGSHGATPKTPGSPAPGRTAPPLPAFVAPPDLGVNCQYRAVPDPSSRPVSPPPSGRVPTTPGQIGAVIATNLGDIGISLANSESPCAVNSFISLARQRFFDNTQCARLVDSPDGGSLLCGGPDVDGSGGPGYEFADEYPANQYRPDDPALRATLLYPRGTVVMATEGPNTNGSQFALIFHDSEMDPQSTVLGTIDPAGLATLDKIARAGIAGNRPSGPPANPVTITSVRIG
>NC_008595.1|WP_003877574.1|3626100_3626667_-|crossover-junction-endodeoxyribonuclease-RuvC
MRVMGVDPGLTRCGLSVVESGRGRTVVALDVDVVRTPSDAPLAERLLSISDAVEHWLATHQPDVVAIERVFSQLNVTTVMGTAQAGGVVALAAAKRGIGVHFHTPSEVKAAVTGNGAANKAQVTAMVTRILALQAKPTPADAADALALAICHCWRAPMIARMARAEALAAQQRQKYKDKVDATLRAAR
>NC_008595.1|WP_011725491.1|3626848_3627460_+|DUF4178-domain-containing-protein
MGSLLVMLAIVLFIASIVVLVVALRRPKQPARPAGRPDPLAADALPQFGPRQLGPGAVVSYGGTDYIVRGSVTYREGPFVWWEHLLEGGDQPLWFSVEEDDGRLQLALWVTRKDLSLRPGDNYVVDGVTFHESERGRASYTTEGTTGLPAGGEMEFVDCTNADETALLSFERWAPDMPWEVSTGKPVSPGEITVYAAPPPSSA
>NC_008595.1|WP_031347718.1|3627479_3627983_+|DUF2617-family-protein
MPLHQLAVTPADVSGEKLGLALNAPVPAPLVSHRLDHPDGGALLLGVLGASHVVAVEHAFSEEISCTARSFGADLPERAEAPGYRLRSRSDARDEASFRRLADDLRDRCARRPGWLGGSFPGDGAALTVLAARPDGAGWRWRTWHLYPDRPAGRGGTVVRTASRWHP
>NC_008595.1|WP_011725493.1|3627979_3628411_+|DUF4247-domain-containing-protein
MSRNRLFVIAGALAVAAVVCLVTGIILLQKNIASYVAGHYHEYARDVNGTRYQCTGSSEQVADTLSEYAEPAARADDNKTEYLRYSNDIVIVGPDGNYPCSIRVEPLSAGYSHRAFVFLGPGFFPGSPSGGAGGTPGGPGGTK
>NC_008595.1|WP_011725494.1|3628455_3628911_+|DUF350-domain-containing-protein
MYLAVEIGTVDLNPVLKGAVATILYFAVGMGVLLVGFYAVDLLTPGKLRQLVFIDRRPNAVVVAGAMYIALTAVIISAIANSYSQLGQGLVGVAVYGLMGVILLGVALLAMHLLIPGSFHEHVEEPQLHPGSFAVALILLAVGGVTAAAVS
>NC_008595.1|WP_011725495.1|3628907_3630479_+|polyamine-aminopropyltransferase
MSTVEVSAPEAAPPSPGRWRALLLAAVAACAACGIIYELALLTLSASLDGGGIVATSLIVAGYIAALGVGALLAKPLLAHAALGFIAVEALLGVVGGLSAAALYVVFAFLDGSVGSTWVLAVSTALIGGLVGAEVPLLMTLLQRGRTAGPADAGRTLANLNAADYLGALLGGLVWPFLLLPQLGMIRGAAATGMINLAAAAVVAIFLLRQVVSARQLALALCALAAALALLATLLLRSADVETTSRQRLYADPIIAYRHTPYQEIVVTRRGDDTRLYLDGGLQFSTRDEYRYTESLVYPALGNGARSVLVLGGGDGLAARELLRQPGISRIVQVELDPAVIEIARTTLRAANGGSLDNPRVRVLTGDAMAWLRGPNPDRFDAVIVDLPDPDTPVLGRLYSTEFYTLAARALAPGGLLVVQAGSPFSTPTAYWRTVSTIRAAGYAVTPYHVHVPTFGDWGFVLAQRGDTPPAPKVPPDAPPLRFLDQRVLQAAVVFSGDVGPRPLEPSTLDNPRIVGDMRHGYD
>NC_008595.1|WP_009977789.1|3630489_3631242_-|YebC/PmpR-family-DNA-binding-transcriptional-regulator
MSGHSKWATTKHKKAVIDARRGKMFARLIKNIEVAARVGGGDPAGNPTLYDAIQKAKKSSVPNENIERARKRGAGEEAGGADWQTITYEGYAPNGVAVLIECLTDNRNRAASEVRVAMTRNGGTMADPGSVSYLFSRKGVVTCEKNGLTEDDILAAVLDAGAEEVEDLGDSFEIICEPTDLVAVRTALQDAGIDYDSAEAGFQPSVTVPLDADGAQKVMRLVDALEDSDDVQDVWTNADIPDEILAQIEE
>NC_008595.1|WP_011725496.1|3631369_3631966_-|pyridoxal-5'-phosphate-synthase-glutaminase-subunit-PdxT
MSAPRIGVLALQGDTREHLAALREAGAESMPVRRRGELEAVDGLVIPGGESTTMSHLLKDLDLLEPLRGLLADGLPAYGACAGMILLASEILDAGAGGREALPLRAIDMTVRRNAFGRQVDSFEGDIAFAGLDVPVRAVFIRAPWVERAGDGVEVLARAAGHVVAVRQGARLATAFHPEMTGDRRIHRLFVDLVTGVV
>NC_008595.1|WP_003875361.1|3631962_3632799_-|acyl-CoA-thioesterase-II
MSIEQILDLEQLEVNIYRGGVFSPDSGYFQRTFGGHVAGQSLVSAVRTVDPRYQVHSLHGYFLRPGDAKERTVFIVERTRDGGSFATRRVNAIQHGEIIFSMGASFQTDQEGIHHQDAMPAAPPPDGLPGLDSIKVFDDAGFKQFEEWDVCIVPREKLQLTPGKASQQQVWFRHRDPLPDDPVLHICALAYMSDLTLLGSAQVTHLDVREHLQVASLDHAMWFMRAFRADEWLLYDQSSPSANGGRSLCQGKIFTQSGEMVAAVMQEGLTRFQRGYRQ
>NC_008595.1|WP_003878553.1|3632808_3633720_-|pyridoxal-5'-phosphate-synthase-lyase-subunit-PdxS
MNTAHSPDGSGRTGTARVKRGMAEMLKGGVIMDVVTPEQAKIAEGAGAVAVMALERVPADIRAQGGVSRMSDPDMIEGIISAVTIPVMAKARIGHFVEAQILQSLGVDYIDESEVLTPADYTHHIDKWKFTVPFVCGATNLGEALRRINEGAAMIRSKGEAGTGDVSNATTHMRAIGGEIRRLMSLSEDELYVAAKELQAPYELVVEVARAGKLPVTLFTAGGIATPADAAMMMQLGAEGVFVGSGIFKSGDPAQRAAAIVKATTFYDDPDVLAKVSRGLGEAMVGINVEQIAQPERLAERGW

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Crispr_ID: NC_008595_8

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_008595_8

4410369-4410459

Orphan

Consensus_repeat	Method
AGCCCGGTGACGATGCCCGCCGCAGCGCGGCGG	CRISPRCasFinder

1 spacers

DinG

The CRISPR arrays of NC_008595_8

>merge|NC_008595|8|4410369-4410459|CRISPRCasFinder
AGCCCGGTGACGATGCCCGCCGCAGCGCGGCGGGAGGAGGAGGCGGGCCATCCCACCCAGCCCGGTGACGATGCCCGCCGCAGCGCGGCGG

>NC_008595|8|8|4410369-4410459|CRISPRCasFinder
AGCCCGGTGACGATGCCCGCCGCAGCGCGGCGG	GAGGAGGAGGCGGGCCATCCCACCC
AGCCCGGTGACGATGCCCGCCGCAGCGCGGCGG

Protein	Signature genes	Signature genes Name	Protein_function
NC_008595.1\|WP_011725978.1\|4402367_4402580_+\|hypothetical-protein	unknown	unknown	unknown
NC_008595.1\|WP_003878975.1\|4403901_4405038_-\|PPE-family-protein	unknown	unknown	gnl\|CDD\|366325
NC_008595.1\|WP_009978799.1\|4400819_4401737_-\|prolyl-oligopeptidase-family-serine-peptidase	unknown	unknown	gnl\|CDD\|226040
NC_008595.1\|WP_003874498.1\|4407130_4408885_-\|glycerol-3-phosphate-dehydrogenase/oxidase	unknown	unknown	gnl\|CDD\|223651
NC_008595.1\|WP_011725976.1\|4395435_4400067_+\|ATP-dependent-helicase	DinG	COG1199_DinG_CAS-IV-A	gnl\|CDD\|137505
NC_008595.1\|WP_009978801.1\|4401928_4402282_+\|DUF732-domain-containing-protein	unknown	unknown	gnl\|CDD\|368380
NC_008595.1\|WP_003874495.1\|4410999_4412178_-\|amidohydrolase	unknown	unknown	gnl\|CDD\|349936
NC_008595.1\|WP_033713311.1\|4413422_4414079_-\|cutinase-family-protein	unknown	unknown	gnl\|CDD\|366455
NC_008595.1\|WP_003874501.1\|4405270_4405558_-\|hypothetical-protein	unknown	unknown	unknown
NC_008595.1\|WP_003874503.1\|4402655_4403792_-\|PPE-family-protein	unknown	unknown	gnl\|CDD\|366325
NC_008595.1\|WP_011725987.1\|4418340_4419654_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|215601
NC_008595.1\|WP_011725984.1\|4415114_4416695_+\|phospho-sugar-mutase	unknown	unknown	gnl\|CDD\|100092
NC_008595.1\|WP_011725983.1\|4414294_4415110_+\|purine-nucleoside-phosphorylase	unknown	unknown	gnl\|CDD\|236183
NC_008595.1\|WP_011725988.1\|4420689_4421697_-\|VWA-domain-containing-protein	unknown	unknown	gnl\|CDD\|184242
NC_008595.1\|WP_023895840.1\|4416546_4417320_-\|uracil-phosphoribosyltransferase	unknown	unknown	gnl\|CDD\|234653
NC_008595.1\|WP_023860891.1\|4406261_4407134_-\|pseudouridine-synthase	unknown	unknown	gnl\|CDD\|211332
NC_008595.1\|WP_003874496.1\|4410509_4410977_+\|gamma-glutamylcyclotransferase	unknown	unknown	gnl\|CDD\|372719
NC_008595.1\|WP_011725979.1\|4405625_4406222_-\|hypothetical-protein	unknown	unknown	unknown
NC_008595.1\|WP_011725986.1\|4417484_4418315_+\|acid-phosphatase	unknown	unknown	gnl\|CDD\|309350
NC_008595.1\|WP_011725981.1\|4412174_4413377_-\|M20-family-metallopeptidase	unknown	unknown	gnl\|CDD\|349921

Protein	Function_ID	Function_description	E-value
NC_008595.1\|WP_003878975.1\|4403901_4405038_-\|PPE-family-protein	gnl\|CDD\|366325	pfam00823, PPE, PPE family. This family named after a PPE motif near to the amino terminus of the domain. The PPE family of proteins all contain an amino-terminal region of about 180 amino acids. The carboxyl terminus of this family are variable, and on the basis of this region fall into at least three groups. The MPTR subgroup has tandem copies of a motif NXGXGNXG. The second subgroup contains a conserved motif at about position 350. The third group are only related in the amino terminal region. The function of these proteins is uncertain but it has been suggested that they may be related to antigenic variation of Mycobacterium tuberculosis.	2.96273e-51
NC_008595.1\|WP_009978799.1\|4400819_4401737_-\|prolyl-oligopeptidase-family-serine-peptidase	gnl\|CDD\|226040	COG3509, LpqC, Poly(3-hydroxybutyrate) depolymerase [Secondary metabolites biosynthesis, transport, and catabolism].	1.4297e-96
NC_008595.1\|WP_003874498.1\|4407130_4408885_-\|glycerol-3-phosphate-dehydrogenase/oxidase	gnl\|CDD\|223651	COG0578, GlpA, Glycerol-3-phosphate dehydrogenase [Energy production and conversion].	0
NC_008595.1\|WP_011725976.1\|4395435_4400067_+\|ATP-dependent-helicase	gnl\|CDD\|137505	PRK09751, PRK09751, putative ATP-dependent helicase Lhr; Provisional.	0
NC_008595.1\|WP_009978801.1\|4401928_4402282_+\|DUF732-domain-containing-protein	gnl\|CDD\|368380	pfam05305, DUF732, Protein of unknown function (DUF732). This family consists of several uncharacterized Mycobacterium tuberculosis and leprae proteins of unknown function.	5.92356e-24
NC_008595.1\|WP_003874495.1\|4410999_4412178_-\|amidohydrolase	gnl\|CDD\|349936	cd08014, M20_Acy1-like, M20 Peptidase aminoacylase 1 subfamily. Peptidase M20 family, uncharacterized subfamily of uncharacterized bacterial proteins predicted as putative amidohydrolases. These are a class of zinc binding homodimeric enzymes involved in hydrolysis of N-acetylated proteins. N-terminal acetylation of proteins is a widespread and highly conserved process that is involved in protection and stability of proteins. Several types of aminoacylases can be distinguished on the basis of substrate specificity. Aminoacylase 1 (ACY1) breaks down cytosolic aliphatic N-acyl-alpha-amino acids (except L-aspartate), especially N-acetyl-methionine and acetyl-glutamate into L-amino acids and an acyl group. However, ACY1 can also catalyze the reverse reaction, the synthesis of acetylated amino acids. ACY1 may also play a role in xenobiotic bioactivation as well as the inter-organ processing of amino acid-conjugated xenobiotic derivatives (S-substituted-N-acetyl-L-cysteine).	0
NC_008595.1\|WP_011725983.1\|4414294_4415110_+\|purine-nucleoside-phosphorylase	gnl\|CDD\|236183	PRK08202, PRK08202, purine nucleoside phosphorylase; Provisional.	2.3098e-131
NC_008595.1\|WP_003874503.1\|4402655_4403792_-\|PPE-family-protein	gnl\|CDD\|366325	pfam00823, PPE, PPE family. This family named after a PPE motif near to the amino terminus of the domain. The PPE family of proteins all contain an amino-terminal region of about 180 amino acids. The carboxyl terminus of this family are variable, and on the basis of this region fall into at least three groups. The MPTR subgroup has tandem copies of a motif NXGXGNXG. The second subgroup contains a conserved motif at about position 350. The third group are only related in the amino terminal region. The function of these proteins is uncertain but it has been suggested that they may be related to antigenic variation of Mycobacterium tuberculosis.	1.69844e-50
NC_008595.1\|WP_011725987.1\|4418340_4419654_+\|hypothetical-protein	gnl\|CDD\|215601	PLN03142, PLN03142, Probable chromatin-remodeling complex ATPase chain; Provisional.	0.000359964
NC_008595.1\|WP_011725984.1\|4415114_4416695_+\|phospho-sugar-mutase	gnl\|CDD\|100092	cd05799, PGM2, This CD includes PGM2 (phosphoglucomutase 2) and PGM2L1 (phosphoglucomutase 2-like 1). The mammalian PGM2 is thought to be a phosphopentomutase that catalyzes the conversion of the nucleoside breakdown products, ribose-1-phosphate and deoxyribose-1-phosphate to the corresponding 5-phosphopentoses. PGM2L1 is thought to catalyze the 1,3-bisphosphoglycerate-dependent synthesis of glucose 1,6-bisphosphate and other aldose-bisphosphates that serve as cofactors for several sugar phosphomutases and possibly also as regulators of glycolytic enzymes. PGM2 and PGM2L1 belong to the alpha-D-phosphohexomutase superfamily which includes several related enzymes that catalyze a reversible intramolecular phosphoryl transfer on their sugar substrates. Other members of this superfamily include phosphoglucosamine mutase (PNGM), phosphoacetylglucosamine mutase (PAGM), the bacterial phosphomannomutase ManB, the bacterial phosphoglucosamine mutase GlmM, and the bifunctional phosphomannomutase/phosphoglucomutase (PMM/PGM). Each of these enzymes has four domains with a centrally located active site formed by four loops, one from each domain. All four domains are included in this alignment model.	0
NC_008595.1\|WP_011725988.1\|4420689_4421697_-\|VWA-domain-containing-protein	gnl\|CDD\|184242	PRK13685, PRK13685, hypothetical protein; Provisional.	0
NC_008595.1\|WP_023895840.1\|4416546_4417320_-\|uracil-phosphoribosyltransferase	gnl\|CDD\|234653	PRK00129, upp, uracil phosphoribosyltransferase; Reviewed.	6.41144e-108
NC_008595.1\|WP_023860891.1\|4406261_4407134_-\|pseudouridine-synthase	gnl\|CDD\|211332	cd02558, PSRA_1, Pseudouridine synthase, a subgroup of the RluA family. This group is comprised of bacterial proteins assigned to the RluA family of pseudouridine synthases. Pseudouridine synthases catalyze the isomerization of specific uridines in an RNA molecule to pseudouridines (5-ribosyluracil, psi). No cofactors are required. The RluA family is comprised of proteins related to Escherichia coli RluA.	1.2786e-117
NC_008595.1\|WP_003874496.1\|4410509_4410977_+\|gamma-glutamylcyclotransferase	gnl\|CDD\|372719	pfam13772, AIG2_2, AIG2-like family. This family is found in bacteria and metazoa.	2.35863e-33
NC_008595.1\|WP_033713311.1\|4413422_4414079_-\|cutinase-family-protein	gnl\|CDD\|366455	pfam01083, Cutinase, Cutinase.	5.54524e-37
NC_008595.1\|WP_011725986.1\|4417484_4418315_+\|acid-phosphatase	gnl\|CDD\|309350	pfam04185, Phosphoesterase, Phosphoesterase family. This family includes both bacterial phospholipase C enzymes EC:3.1.4.3, but also eukaryotic acid phosphatases EC:3.1.3.2.	8.25623e-43
NC_008595.1\|WP_011725981.1\|4412174_4413377_-\|M20-family-metallopeptidase	gnl\|CDD\|349921	cd05672, M20_ACY1L2-like, M20 Peptidase aminoacylase 1-like protein 2-like, amidohydrolase subfamily. Peptidase M20 family, aminoacylase 1-like protein 2 (ACY1L2; amidohydrolase)-like subfamily. This group contains many uncharacterized proteins predicted as amidohydrolases, including gene products of abgA and abgB that catalyze the cleavage of p-aminobenzoyl-glutamate, a folate catabolite in Escherichia coli, to p-aminobenzoate and glutamate. p-Aminobenzoyl-glutamate utilization is catalyzed by the abg region gene product, AbgT. This subfamily includes Staphylococcus aureus antibiotic resistance factor HmrA that has been shown to participate in methicillin resistance mechanisms in vivo in the presence of beta-lactams. Aminoacylase 1 (ACY1) proteins are a class of zinc binding homodimeric enzymes involved in hydrolysis of N-acetylated proteins. N-terminal acetylation of proteins is a widespread and highly conserved process that is involved in the protection and stability of proteins. Several types of aminoacylases can be distinguished on the basis of substrate specificity. ACY1 breaks down cytosolic aliphatic N-acyl-alpha-amino acids (except L-aspartate), especially N-acetyl-methionine and acetyl-glutamate into L-amino acids and an acyl group. However, ACY1 can also catalyze the reverse reaction, the synthesis of acetylated amino acids. ACY1 may also play a role in xenobiotic bioactivation as well as the inter-organ processing of amino acid-conjugated xenobiotic derivatives (S-substituted-N-acetyl-L-cysteine).	2.84283e-153

>NC_008595.1|WP_003874498.1|4407130_4408885_-|glycerol-3-phosphate-dehydrogenase/oxidase
MSDPIHALGEPGSPASALGPRQRAAAWDRLGAEQFDVVVIGGGVVGSGCALDAATRGLKVALVEARDFASGTSSRSSKMFHGGLRYLEQLEFGLVREALYERELSLTTLAPHLVKPMPFLFPLTNRLWERPYIAAGIFLYDRLGGAKSVPAQKHLTRAGALRLCPGLKRSALIGGIRYYDTIVDDARHTLTVARTAAHYGVVVRNSTQVVALLREGDRVTGVRVRDSEDGSVTEVRGHVVVNATGVWTDEIQALSKQRGRFQVRASKGVHVVVPRDRIVSDVAIILRTEKSVMFVIPWGSHWIIGTTDTDWDLDLAHPAATKADIDYILSTVNTVLAIPLTHADIDGVYAGLRPLLAGESEETSKLSREHAVAVPAPGLVAIAGGKYTTYRVMAADAIDAAAQFIPARVAPSITEKVSLLGADGYFALINQAEHVAQLRGLHPYRVRHLLDRYGSLIGDVLALAADRPDLLNPITEAPGYLRVEALYAVTAEGALHLEDILARRMRISIEYSHRGVDCAREVADVVAPVLGWTAGDVEREVANYTARVQAEILSQAQPDDVSADELRASAPEARAEILEPVPLN
>NC_008595.1|WP_023860891.1|4406261_4407134_-|pseudouridine-synthase
MRPVPLPVRDGLGPARVRLRGGPVLAELTARFGAAARAKVLAAEVVTADGAVVDEATVLPAGASVYLYRELPDEVVVPFDLPVLHRDDDIVVVDKPHFLATMPRGRHVAQTALVRLRRELGLPELSPAHRLDRLTAGVLLFTARREVRGAYQTLFSRGLVDKTYLARAAVDPALVFPRVLAGRIVKHRGRMQAVCEPGPPNALTEVELLSPDGLYRLRPRTGRTHQLRLQMASLGIPIIGDPLYPNMIDVPADDFSTPLQLLAQRIEFDDPRTGARRVFVSRRTLDDPGP
>NC_008595.1|WP_011725979.1|4405625_4406222_-|hypothetical-protein
MRRQLRIPERANDAETALLRYLLYGLLPAWFIPALLDWNQHRRSRIEITSGTRESLIHLLMMAEVGVPITLVLLCEINPLVLSTILASIAAHEATALWDVTAAERSGRRVTTWEQHVHSFLESLPIMAASALGCLHWREVRELARGARSRDAWRLRWKQNPLPGGYLAAVAAAVAAAIVVPYGEELYRCVTKTDRTLR
>NC_008595.1|WP_003874501.1|4405270_4405558_-|hypothetical-protein
MRHGTVAAAAALLLAAGVIAAAPPARAGCQYGGPVLSKCDGPVQPDGTWQRCVAVTRLIPNGASSYLVPDGHCEQLGPDQHPADLAFADPPGHID
>NC_008595.1|WP_003878975.1|4403901_4405038_-|PPE-family-protein
MDLFAPPEVTSTLIHTGPGAGSLIEAAAAWQRVAVELENSVSSYASTLSSLIESWDGPSAMAMLQSVQPYLLWLRETAQQSAQLANSAEAAATAFGTVRSTVVHPSVVSANRTRLAQLLATNRFGTNTAAIAETENEYQTMWANNSAALSRYQAASSQATSPLTQFNSPLAVTDPGGTANQQAAVMKASVDSSGSSVGSVLNDLNMPGGFDPNAGWFNYFSTWGNQFISSGFPINLLGVWAQLATAQGVASVGGDIGSGLSEGLGATTASLANAIKGIGAGAVAPSGAMGVGVSLGKLTAPPAVVGLLPGTQTGVQLASAASPLPAAESGFPLMPMMVPPPTTSAGTGWRKRKQQKYEDVAYGREVKGKVMPRNPSAG
>NC_008595.1|WP_003874503.1|4402655_4403792_-|PPE-family-protein
MDFGILPPEVTSALIHAGPGAWSWIEAAGVWQQLSMELEQSASSYTAELAALSTTWQGPSALAMTRALEPYVDWLRITAQQCQEIATSVQTATAAFELTHWTVVHPSLVAANRARLAMLLATNFFGINYPAIAETEAEYHAMWVNNSAAMYRYAATSATAVRLPRFTEPPQVANPSGVSTQAAMVPATNAADSGTQTGVAGTLQAASTAFFDPNTGWFKYWSTWGNQFLAASGFPINLIGVLAQLQTASGFQSLGADVAGGLAEGTAALSAAEVRLVSAVGAAGSSLAPRAALGVGISLGNLTMPPATVGMLGSQAPVQLASAASPLATGAGQPPMLPMTPMRPGGNGTRRRNGRDYDDIEYGAELPGTVMQRPPSAG
>NC_008595.1|WP_011725978.1|4402367_4402580_+|hypothetical-protein
MIPRLLAGMACVAIALGPPVGAAAPAGADPGPFAHLNCACDQPDPPGGATPRDAMNQGIRQGLSAPPAAE
>NC_008595.1|WP_009978801.1|4401928_4402282_+|DUF732-domain-containing-protein
MTSTQIRKRARPRSLVVAGLLPLAGLLGVITTPAYATSADDAFLAALKAKGINYESPDAAVNSGHTVCHELDMGQTPEQVANNVLSSSTLDSYHAGYFVGVSIKAYCPKYAAAAAGS
>NC_008595.1|WP_009978799.1|4400819_4401737_-|prolyl-oligopeptidase-family-serine-peptidase
MAYARWLWLAVLAVCVVGCGVRHVSAASARDISGTFRSGGMDRTYMLHVPAGDPVGLVLSLHGGGGTGIAQRGLTGFDAVADAHNLLVVYPDGYEKSWADGRGASPADRHHVDDVAFLVGLVTKLQNDYRVAPGHVFVTGMSNGGFMSNRLACDRADVFAAVAPVAGTLGVGVACNPSRPVSVWAAHGTADPLVPFKGGAVRGRGGLSHAVSAEAMVDKWRKVDGCQGDPSMELLPDARDGTVVHRFDSTSCAASTEVVFYRIDKGGHTWPGGKQYLPAAVIGPTTHTLDGSEAIAEFFLAHARD
>NC_008595.1|WP_011725976.1|4395435_4400067_+|ATP-dependent-helicase
MSTRAEPRPSDPLGRFSAITREWFTSTFAAPTTAQAQAWSAIADGHNTLVIAPTGSGKTLAAFLWALDSLAGQAERAPGTRVLYVSPLKALAVDVERNLRTPLAGLTRIAERAGLPAPDISVGVRSGDTPPAVRRQLINRPPDVLITTPESLFLMLTSAARETLAGVQTVIVDEIHAIAGGKRGAHLALSLERLDALREGRPAQRIGLSATVRPPDELARFLSGAAPGTRTTVVAPPSAKTVELSVQVPVPDMANLANNTIWPDVENRLVDLIEAHGSTIVFANSRRLAERLTARLNEIHAERSGVELSATANPKVAGGAPAHIMASGQTYGVEPILARAHHGSVSKEQRALVEEDLKRGLLKAVVATSSLELGIDMGAVDLVIQVEAPPSVASGLQRIGRAGHQVGEVSRGVLFPKHRTDLIGCAVTVQRMLAGQIETMRVPANPLDILAQQTVAAAALEPLDADRWFDTVRRAAPFATLPRSIYEATLDLLSGKYPSTEFAELRPRLVYDRNTGTLTARPGAQRLAVTSGGAIPDRGLFTVYLASEAEKPSRVGELEEEMVYESRPGDVISLGATSWRITEITHDRVLVIPAPGQPARLPFWRGDGVGRPAELGAALGAFTGELAGLSREEFDSRCAALGFDAYAVDNLYGLFDEQRTAAGVVPTDTTLLVERFRDELGDWRVILHSPYGLGVNGPLALAVGRRLRERYGIDEKPTASDDGVVVRLPDTVSDFASDGGDTPPGAELFVFDADEIDPIVTAEVGGSALFASRFRECAARALLLPRRHPGRRSPLWQQRQRAAQLLEVARKYPDFPVVLETVRECLQDVYDVPALVALMAGIAQRRVRVLEVETQRPSPFAASLLFGYVGAFMYEGDSPLAERRAAALSLDSTLLAELLGRVELRELLDPEVVAATARALQHLAPERAARDAEAVADLLRLLGPLTEDEVVARAGGADAVEVRGWLEGLRAARRAVPVSFAGRSWWVAIEDIGRLRDGLGIAVPLGVPAAFTEEVADPLGELLGRYARTHTPFSTAEAAARFGLGLRVTADVLGRLADPSTSQGRLVRGDFVAARPSEPGGVLGAEQWCDADVLRILRRRSLAALRAQVEPVSTAAYGRFLPAWHRVGAAESSRAPGHSGLDGLMSVIEQLAGVRLPASALEPLVLAPRVRDYSPALLDELLATGEVTWSGAGSISGSDGWIALHPSESAPLTLQGPADIELGEAHRAILDVLAGGGGYFFRQLATDGVSDAELKAALWELVWAGWITGDTFAPVRALLGGGGTRRRSAPAHRAQRPPRLSRYSVAHPQARPADTTVAGRWSVLPPPEPDSTVRAHFQAELLLGRHGVLTRGAVAAEGVAGGFATLYKVLSTFEDAGRCQRGYFIESLGGAQFAVASTVDRLRGFADGVDPQRPEYRAIVLAAADPANPYGAALPWPASSADGARPGRKAGALVVLVDGELAWFLERGGRSLLTFTDDPAAQHAAAAALAGLVSARRVAAILVERIDGVPALAPRGDGAAGNDALTALADAGFARTPRGMRLR
>NC_008595.1|WP_003874496.1|4410509_4410977_+|gamma-glutamylcyclotransferase
MPLYAAYGSNMDPEQMLKRAPHSPMAGTGWLHGWRLTFGGEDIGWEGALATVVEDPGSKVFVVLYDMTPADEKNLDRWEGSEFGVHKKIRCRVDRISSDTTTDPVLAWLYVLDAWEGGLPSARYLGVMADAAEIAGAPADYVHDLRTRPARNIGP
>NC_008595.1|WP_003874495.1|4410999_4412178_-|amidohydrolase
MSLADAATSWLAAHNQDLIEWRRHIHRYPELGRQEYATTQFVAERLAEAGLNPKVLPGGTGLTCDLGPEHEPRIALRADMDALPMAERTGAPYASTMPNVAHACGHDAHTAILLGTALVLASVPELPVGVRLIFQAAEELMPGGAIDAIAAGAITGVSRIFALHCDPRLEVGQIAVRHGPITSAADQIEITLYSPGGHTSRPHLTADLVYGLGTLITGLPGVLSRRIDPRNGTVLVWGAVNAGVAANAIPQTGVLAGTVRTASRQTWVGLEEVIRETVSGLLAPLGIEHTLQYRRGVPPVVNEDVSTRILTHAIEALGPDALADTRQSGGGEDFSWYLEEIPGAMARLGVWPGVGPQLDLHQPTFNLDERALAIGVRVMANIVEQSALFQVF
>NC_008595.1|WP_011725981.1|4412174_4413377_-|M20-family-metallopeptidase
MPPVGSDSPLDSVEDVVRRRGADLVELSHAIHAEPELAFAEHRSCAKAQALVAERGFEITAAAGGLDTAFRADFGSGQLTIGVCAEYDALPEIGHACGHNIIAASAVGTALALAEVADDLGLRVALVGTPAEEAGGGKALLLKAGVFDDISAAVMLHPGPADIAAARSLALSEAIVRYRGKESHAAVAPHLGVNALDAVTVAQVAVGLLRQQLAPGQLVHGIVTDGGQAVNVIPGHASLQYAMRAVESDSLRELEGRMYACFAAGAMAAGCEYEIDNPAPAYDELKPDAWLANIFREEMCRLGRQPVAPEYEAALPMGSTDMGNVTQALPGIHPVVGVESGGAMVHQRAFADAAAGPSADRAVIEGAIMLARTVVALAQTPAERDRVLAAHERRRGGAHP
>NC_008595.1|WP_033713311.1|4413422_4414079_-|cutinase-family-protein
MVGPAIGIVVAVALSVVAITCGPAPRAAADGCPDVQLIFARGTAEPPGLGAVGDALFAALQPALGNRNVDAYAVNYPASYNFLTTADGANDARDHIAEMVDRCPSTRLVLGGFSQGAAAVSMLAGVPPVGQRIGNFGSAPPLDPGLASKIAAVAVFGNPGNRFNTPLSTTGAFAGRAIDLCSDGDPVCVVGGRDRDAHHVYEDPPYPAQAAGFIAGRV
>NC_008595.1|WP_011725983.1|4414294_4415110_+|purine-nucleoside-phosphorylase
MAETPSNPGELARQAAAVIGERTGVAEHDVAIVLGSGWSPAVAALGTPTAVLPQAELPGFRPPTAVGHTGELVSMRIGEHRVLVLVGRIHAYEGHDLCHVVHPVRAACAAGVRAVVLTNAAGGLRPDLAVGEPVLISDHLNLTGRSPLVGPQFVDLTDAYSPRLRELARQADPTLAEGVYAGLPGPHYETPAEIRMLRTLGADLVGMSTVHETIATRAAGAEVLGVSLVTNLAAGISGEPLSHTEVLAAGAASATRMGALLALILRQLPRF
>NC_008595.1|WP_011725984.1|4415114_4416695_+|phospho-sugar-mutase
MTPEEWIAHDPDPRTAAELAACDAAELAARFARPLRFGTAGLRGPVRGGPDAMNVAVVSRASWALAQVLKRRGPAGARVIVGRDARHGSAVFATVAAEVIAAQGFSVLLLPGPAPTPVVAFAVRHTGAAAGVQITASHNPPTDNGYKVYDGGGIQIVSPTDHQIEAAMADAPPADEIRRTPVPPAHTDLVQRYIERAAGVRRGTGSVRVALTALHGVGGTVAVDALHRAGFGRIHTVASQFAPDPDFPTVAFPNPEEPGATDALLTLAADVDADVAIALDPDADRCAVGIPDASGWRMLSGDETGWLLGDYLLSQPQRADRPVVASTVVSSRMLSAIAARHGAVHVETLTGFKWLARADAEVPGGTLVYAYEEAIGHCVDPAAVRDKDGISAAVLVCDLVAALIARGGSVSGRLDELARRHGVHDVAAVSRRVGTDGAAELMRRLRTSPPETLAGFGVALTDITDALIFTGGDDDTSVRLVVRPSGTEPKVKCYLEIRCAPSDDLASSRRRARALRELLVATVRSW
>NC_008595.1|WP_023895840.1|4416546_4417320_-|uracil-phosphoribosyltransferase
MDVCVIDHPLAAARLTVLRDERTDTAGFRAALRDLTLMLVYEASRDAPRKSVRIRTPVAAAAGTRLVNPPLLVPVLRAGLGMVDPAQAALPEAEVGFVGVARDEQTHRPVPYLAALPDKLAGRSVMVLDPMLATGGSMAHTLGLLQRRGATDITVLCVVAAPEGLAAVGETAPDARVFTAAVDKGLNKAAYIVPGLGDAGDRQFGPNLFTSSAPSRPEAPAGRGRAAAKMPGRRSARSESPSSTSPSARSRKAAPPA
>NC_008595.1|WP_011725986.1|4417484_4418315_+|acid-phosphatase
MAAVALAASPLTPRTSLAAAAIPQPSHIVIVVEENRSESGIIGNKSAPFITALAASGANMTQSFAETHPSEPNYLALFAGNTFGVTKDLCPVNAGAAPNLGSELLAAGYTFAGYAEGLPSPGSPVCSAGKYARKHVPWANFTNVPAASSLPFSAFPMGNYASLPTVSFVIPNNDNNMHDGSIAQADAWLNRQLSGYANWALANNSLLIVTFDEDDNSNVGASRNQIPTVFYGAHVRPGNYAEQINHYNVLATLEQMYGLPKTGYAAGAAPITDIWG
>NC_008595.1|WP_011725987.1|4418340_4419654_+|hypothetical-protein
MAADLVPIRLSLSAGDRYTVWAPRWRDSGDEWEAFLGKDEDLYVFSSVADLVAFVRSDEDNDLTDHPAWTRLRTAHAHKFEPAKDKQFDLVAVEELVSEKPTEESVTALAGVLAIVSSIGSVCELAAVSKFFNGNPALGTVSGGIEHFTGKAGAKRWHAIAEIIARGWDDVLGAIDDIATTPEVEEALSAKAEDELAEERDDEETDEADEAAEAPADATEPDEEALENDEADGEPDDDADETETRAAGDTVVLGGDKDFWLQVGIDPIRIITSSGTFYTLRCYLDDQPIFLGRNGRISVFTSERALARYLADEHDHDLADLSTYDDIRTAATDGSLEVEITDDNIYVLSGLADDLADGPDAVDRDQLELAVEVLRDIGDYSEDSTVDKALEPGRPLGKLVAAVLEPGSVAKPSPPYAAAVREWEKLEQFVDGRLRRE
>NC_008595.1|WP_011725988.1|4420689_4421697_-|VWA-domain-containing-protein
MKLPLLGPVSLAGFQHAWFFLALLAVLLVIGLYVVQQFARRRRVLRFANMEVLERVAPPHPSRWRHVPTILLATSLVLLTTAMAGPTSDVRIPLNRAVVMLVIDVSESMASTDVPPNRLAAAKEAGKQFADQLTPAINLGLVEFAANATLLVPPTTNRAAVKAGIDSLQPAPKTATGEGIFTALQAIATVGSVMGGGEGPPPARIVLESDGAENVPLDPNAPQGAFTAARAAKAEGVQISTISFGTPYGTVDYEGATIPVPVDDQTLQKICEITDGQAFHADSLDSLKNVYSTLQRQIGYETVKGDASMAWMLLGAVVLAGAVLAGLLLNRRLPA

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity
NC_008595_7	7.1\|3625457\|29\|NC_008595\|CRISPRCasFinder	3625457-3625485	29	NC_008595.1	3835312-3835340	1	0.966
NC_008595_7	7.1\|3625457\|29\|NC_008595\|CRISPRCasFinder	3625457-3625485	29	NC_008595.1	3835365-3835393	1	0.966
NC_008595_7	7.1\|3625457\|29\|NC_008595\|CRISPRCasFinder	3625457-3625485	29	NC_008595.1	3862535-3862563	1	0.966
NC_008595_7	7.1\|3625457\|29\|NC_008595\|CRISPRCasFinder	3625457-3625485	29	NC_008595.1	3862588-3862616	1	0.966
NC_008595_7	7.1\|3625457\|29\|NC_008595\|CRISPRCasFinder	3625457-3625485	29	NC_008595.1	5146009-5146037	1	0.966
NC_008595_2	2.1\|1474613\|28\|NC_008595\|CRISPRCasFinder	1474613-1474640	28	NC_008595.1	1557827-1557854	2	0.929
NC_008595_7	7.1\|3625457\|29\|NC_008595\|CRISPRCasFinder	3625457-3625485	29	NC_008595.1	3699788-3699816	2	0.931

1. spacer 7.1|3625457|29|NC_008595|CRISPRCasFinder matches to position: 3835312-3835340, mismatch: 1, identity: 0.966

tgcgccgctcctcctcatcgcttcgctct	CRISPR spacer
tgcgccgctcctcctcatcgctgcgctct	Protospacer
********************** ******

2. spacer 7.1|3625457|29|NC_008595|CRISPRCasFinder matches to position: 3835365-3835393, mismatch: 1, identity: 0.966

tgcgccgctcctcctcatcgcttcgctct	CRISPR spacer
tgcgccgctcctcctcatcgctgcgctct	Protospacer
********************** ******

3. spacer 7.1|3625457|29|NC_008595|CRISPRCasFinder matches to position: 3862535-3862563, mismatch: 1, identity: 0.966

tgcgccgctcctcctcatcgcttcgctct	CRISPR spacer
tgcgccgctcctcctcatcgctacgctct	Protospacer
********************** ******

4. spacer 7.1|3625457|29|NC_008595|CRISPRCasFinder matches to position: 3862588-3862616, mismatch: 1, identity: 0.966

tgcgccgctcctcctcatcgcttcgctct	CRISPR spacer
tgcgccgctcctcctcatcgctacgctct	Protospacer
********************** ******

5. spacer 7.1|3625457|29|NC_008595|CRISPRCasFinder matches to position: 5146009-5146037, mismatch: 1, identity: 0.966

tgcgccgctcctcctcatcgcttcgctct	CRISPR spacer
tgcgccgctcctcctcatcgctgcgctct	Protospacer
********************** ******

6. spacer 2.1|1474613|28|NC_008595|CRISPRCasFinder matches to position: 1557827-1557854, mismatch: 2, identity: 0.929

cgcgtcgcgacgatgcagagcgcagcga	CRISPR spacer
cgcgccgcgacgatgcagagcgaagcga	Protospacer
****.***************** *****

7. spacer 7.1|3625457|29|NC_008595|CRISPRCasFinder matches to position: 3699788-3699816, mismatch: 2, identity: 0.931

tgcgccgctcctcctcatcgcttcgctct	CRISPR spacer
tgcgacgctcctcctcatcgctgcgctct	Protospacer
**** ***************** ******

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NC_008595_4	4.1\|2505654\|25\|NC_008595\|CRISPRCasFinder	2505654-2505678	25	NZ_AP022607	Mycobacterium branderi strain JCM 12687 plasmid pJCM12687	141033-141057	3	0.88
NC_008595_4	4.1\|2505654\|25\|NC_008595\|CRISPRCasFinder	2505654-2505678	25	NZ_CP023738	Methylosinus trichosporium OB3b plasmid pOB3b1, complete sequence	106673-106697	4	0.84
NC_008595_4	4.1\|2505654\|25\|NC_008595\|CRISPRCasFinder	2505654-2505678	25	NZ_CP039340	Ralstonia solanacearum strain UW386 plasmid pUW386, complete sequence	938214-938238	4	0.84
NC_008595_8	8.1\|4410402\|25\|NC_008595\|CRISPRCasFinder	4410402-4410426	25	CP036360	Agrobacterium sp. 33MFTa1.1 plasmid p_JBx_073812, complete sequence	131283-131307	4	0.84
NC_008595_1	1.18\|279608\|35\|NC_008595\|CRT	279608-279642	35	NZ_CP011666	Streptomyces sp. Mg1 plasmid pSMg1-2, complete sequence	2922-2956	5	0.857
NC_008595_1	1.18\|279608\|35\|NC_008595\|CRT	279608-279642	35	NZ_CP011666	Streptomyces sp. Mg1 plasmid pSMg1-2, complete sequence	129278-129312	5	0.857
NC_008595_2	2.1\|1474613\|28\|NC_008595\|CRISPRCasFinder	1474613-1474640	28	NC_016138	Pseudomonas aeruginosa plasmid pUM505, complete sequence	39609-39636	5	0.821
NC_008595_2	2.1\|1474613\|28\|NC_008595\|CRISPRCasFinder	1474613-1474640	28	NC_019202	Pseudomonas aeruginosa plasmid pKLC102, complete sequence	59210-59237	5	0.821
NC_008595_2	2.1\|1474613\|28\|NC_008595\|CRISPRCasFinder	1474613-1474640	28	NZ_CP021032	Rhizobium sp. NXC14 plasmid pRspNXC14b, complete sequence	651551-651578	5	0.821
NC_008595_2	2.1\|1474613\|28\|NC_008595\|CRISPRCasFinder	1474613-1474640	28	NZ_CP006990	Rhizobium sp. IE4771 plasmid pRetIE4771d, complete sequence	332447-332474	5	0.821
NC_008595_6	6.1\|3515422\|31\|NC_008595\|CRISPRCasFinder	3515422-3515452	31	NZ_CP017941	Phyllobacterium zundukense strain Tri-48 plasmid unnamed1, complete sequence	248354-248384	5	0.839
NC_008595_2	2.1\|1474613\|28\|NC_008595\|CRISPRCasFinder	1474613-1474640	28	NZ_CP017077	Novosphingobium resinovorum strain SA1 plasmid pSA2, complete sequence	815864-815891	6	0.786
NC_008595_2	2.1\|1474613\|28\|NC_008595\|CRISPRCasFinder	1474613-1474640	28	NZ_CP013104	Paraburkholderia caribensis strain MWAP64 plasmid 1, complete sequence	1335243-1335270	6	0.786
NC_008595_2	2.1\|1474613\|28\|NC_008595\|CRISPRCasFinder	1474613-1474640	28	NZ_CP012748	Paraburkholderia caribensis MBA4 plasmid unnamed, complete sequence	1916974-1917001	6	0.786
NC_008595_2	2.1\|1474613\|28\|NC_008595\|CRISPRCasFinder	1474613-1474640	28	NZ_CP018865	Arthrobacter crystallopoietes strain DSM 20117 plasmid pLDW-10, complete sequence	127-154	6	0.786
NC_008595_2	2.1\|1474613\|28\|NC_008595\|CRISPRCasFinder	1474613-1474640	28	NZ_CP018865	Arthrobacter crystallopoietes strain DSM 20117 plasmid pLDW-10, complete sequence	226958-226985	6	0.786
NC_008595_2	2.1\|1474613\|28\|NC_008595\|CRISPRCasFinder	1474613-1474640	28	NZ_CP014580	Burkholderia sp. OLGA172 plasmid pOLGA1, complete sequence	167187-167214	6	0.786
NC_008595_2	2.1\|1474613\|28\|NC_008595\|CRISPRCasFinder	1474613-1474640	28	MN175604	Gordonia phage PhorbesPhlower, complete genome	9914-9941	6	0.786
NC_008595_2	2.1\|1474613\|28\|NC_008595\|CRISPRCasFinder	1474613-1474640	28	NC_031267	Gordonia phage Lucky10, complete genome	9949-9976	6	0.786
NC_008595_7	7.1\|3625457\|29\|NC_008595\|CRISPRCasFinder	3625457-3625485	29	NZ_CP017765	Bacillus subtilis strain 29R7-12 plasmid unnamed2, complete sequence	3317-3345	6	0.793
NC_008595_7	7.1\|3625457\|29\|NC_008595\|CRISPRCasFinder	3625457-3625485	29	NZ_CP017765	Bacillus subtilis strain 29R7-12 plasmid unnamed2, complete sequence	9137-9165	6	0.793
NC_008595_7	7.1\|3625457\|29\|NC_008595\|CRISPRCasFinder	3625457-3625485	29	NZ_CP017765	Bacillus subtilis strain 29R7-12 plasmid unnamed2, complete sequence	14947-14975	6	0.793
NC_008595_7	7.1\|3625457\|29\|NC_008595\|CRISPRCasFinder	3625457-3625485	29	NC_019849	Sinorhizobium meliloti GR4 plasmid pRmeGR4d, complete sequence	1642721-1642749	6	0.793
NC_008595_7	7.1\|3625457\|29\|NC_008595\|CRISPRCasFinder	3625457-3625485	29	NC_017326	Sinorhizobium meliloti SM11 plasmid pSmeSM11d, complete sequence	1582909-1582937	6	0.793
NC_008595_7	7.1\|3625457\|29\|NC_008595\|CRISPRCasFinder	3625457-3625485	29	NC_017323	Sinorhizobium meliloti BL225C plasmid pSINMEB02, complete sequence	1187930-1187958	6	0.793
NC_008595_7	7.1\|3625457\|29\|NC_008595\|CRISPRCasFinder	3625457-3625485	29	NZ_CP009146	Sinorhizobium meliloti strain RMO17 plasmid pSymB, complete sequence	1567673-1567701	6	0.793
NC_008595_7	7.1\|3625457\|29\|NC_008595\|CRISPRCasFinder	3625457-3625485	29	NC_018701	Sinorhizobium meliloti Rm41 plasmid pSYMB, complete sequence	1615421-1615449	6	0.793
NC_008595_7	7.1\|3625457\|29\|NC_008595\|CRISPRCasFinder	3625457-3625485	29	NZ_CP023428	Bacillus subtilis strain TLO3 plasmid pBsTLO3, complete sequence	6265-6293	6	0.793
NC_008595_7	7.1\|3625457\|29\|NC_008595\|CRISPRCasFinder	3625457-3625485	29	NZ_CP021802	Sinorhizobium meliloti strain USDA1021 plasmid psymB, complete sequence	214329-214357	6	0.793
NC_008595_7	7.1\|3625457\|29\|NC_008595\|CRISPRCasFinder	3625457-3625485	29	NZ_CP021820	Sinorhizobium meliloti strain M162 plasmid psymB, complete sequence	279255-279283	6	0.793
NC_008595_7	7.1\|3625457\|29\|NC_008595\|CRISPRCasFinder	3625457-3625485	29	NZ_CP021831	Sinorhizobium meliloti strain HM006 plasmid psymB, complete sequence	198920-198948	6	0.793
NC_008595_7	7.1\|3625457\|29\|NC_008595\|CRISPRCasFinder	3625457-3625485	29	NZ_CP021814	Sinorhizobium meliloti strain M270 plasmid psymB, complete sequence	1511017-1511045	6	0.793
NC_008595_7	7.1\|3625457\|29\|NC_008595\|CRISPRCasFinder	3625457-3625485	29	NZ_CP021810	Sinorhizobium meliloti strain Rm41 plasmid psymB, complete sequence	739318-739346	6	0.793
NC_008595_7	7.1\|3625457\|29\|NC_008595\|CRISPRCasFinder	3625457-3625485	29	NZ_CP021218	Sinorhizobium meliloti RU11/001 plasmid pSymB, complete sequence	104032-104060	6	0.793
NC_008595_7	7.1\|3625457\|29\|NC_008595\|CRISPRCasFinder	3625457-3625485	29	NZ_CP026527	Sinorhizobium meliloti strain AK21 plasmid pSymB, complete sequence	1625808-1625836	6	0.793
NC_008595_7	7.1\|3625457\|29\|NC_008595\|CRISPRCasFinder	3625457-3625485	29	NZ_CP015223	Bacillus subtilis strain HRBS-10TDI13 plasmid unnamed, complete sequence	3425-3453	6	0.793
NC_008595_7	7.1\|3625457\|29\|NC_008595\|CRISPRCasFinder	3625457-3625485	29	NZ_CP021508	Bacillus subtilis subsp. subtilis strain SRCM101441 plasmid pBL1441-1	6497-6525	6	0.793
NC_008595_7	7.1\|3625457\|29\|NC_008595\|CRISPRCasFinder	3625457-3625485	29	NC_003078	Sinorhizobium meliloti 1021 plasmid pSymB, complete sequence	109426-109454	6	0.793
NC_008595_7	7.1\|3625457\|29\|NC_008595\|CRISPRCasFinder	3625457-3625485	29	NZ_CP019586	Sinorhizobium meliloti strain CCMM B554 (FSM-MA) plasmid pSymB, complete sequence	112148-112176	6	0.793
NC_008595_7	7.1\|3625457\|29\|NC_008595\|CRISPRCasFinder	3625457-3625485	29	NZ_CP043503	Bacillus paralicheniformis strain A4-3 plasmid unnamed2, complete sequence	5510-5538	6	0.793
NC_008595_7	7.1\|3625457\|29\|NC_008595\|CRISPRCasFinder	3625457-3625485	29	NC_007956	Bacillus subtilis plasmid pLS30 DNA, complete sequence	3902-3930	6	0.793
NC_008595_7	7.1\|3625457\|29\|NC_008595\|CRISPRCasFinder	3625457-3625485	29	NZ_CP021799	Sinorhizobium meliloti strain USDA1106 plasmid psymB, complete sequence	176963-176991	6	0.793
NC_008595_7	7.1\|3625457\|29\|NC_008595\|CRISPRCasFinder	3625457-3625485	29	NC_001765	Bacillus subtilis plasmid pTA1015, complete sequence	3112-3140	6	0.793
NC_008595_7	7.1\|3625457\|29\|NC_008595\|CRISPRCasFinder	3625457-3625485	29	NC_001766	Bacillus subtilis plasmid pTA1060, complete sequence	2710-2738	6	0.793
NC_008595_7	7.1\|3625457\|29\|NC_008595\|CRISPRCasFinder	3625457-3625485	29	NZ_CP021828	Sinorhizobium meliloti strain KH35c plasmid psymB, complete sequence	1359399-1359427	6	0.793
NC_008595_7	7.1\|3625457\|29\|NC_008595\|CRISPRCasFinder	3625457-3625485	29	NZ_CP041371	Bacillus sp. M4U3P1 plasmid unnamed2, complete sequence	4103-4131	6	0.793
NC_008595_7	7.1\|3625457\|29\|NC_008595\|CRISPRCasFinder	3625457-3625485	29	NC_017194	Bacillus subtilis subsp. natto BEST195 plasmid pBEST195S, complete sequence	3131-3159	6	0.793
NC_008595_7	7.1\|3625457\|29\|NC_008595\|CRISPRCasFinder	3625457-3625485	29	NZ_CP021823	Sinorhizobium meliloti strain KH46 plasmid psymB, complete sequence	1475947-1475975	6	0.793
NC_008595_7	7.1\|3625457\|29\|NC_008595\|CRISPRCasFinder	3625457-3625485	29	NZ_CP021795	Sinorhizobium meliloti strain USDA1157 plasmid psymB, complete sequence	1025565-1025593	6	0.793
NC_008595_7	7.1\|3625457\|29\|NC_008595\|CRISPRCasFinder	3625457-3625485	29	NZ_CP021806	Sinorhizobium meliloti strain T073 plasmid psymB, complete sequence	1064250-1064278	6	0.793
NC_008595_7	7.1\|3625457\|29\|NC_008595\|CRISPRCasFinder	3625457-3625485	29	NZ_CP019484	Sinorhizobium meliloti strain B401 plasmid pSymB, complete sequence	319191-319219	6	0.793
NC_008595_7	7.1\|3625457\|29\|NC_008595\|CRISPRCasFinder	3625457-3625485	29	NZ_CP014472	Bacillus subtilis subsp. natto strain CGMCC 2108 plasmid unnamed1, complete sequence	3113-3141	6	0.793
NC_008595_7	7.1\|3625457\|29\|NC_008595\|CRISPRCasFinder	3625457-3625485	29	NZ_CP019487	Sinorhizobium meliloti strain B399 plasmid pSym, complete sequence	106787-106815	6	0.793
NC_008595_7	7.1\|3625457\|29\|NC_008595\|CRISPRCasFinder	3625457-3625485	29	NC_020560	Sinorhizobium meliloti 2011 plasmid pSymB, complete sequence	109426-109454	6	0.793
NC_008595_7	7.1\|3625457\|29\|NC_008595\|CRISPRCasFinder	3625457-3625485	29	NC_006825	Bacillus subtilis plasmid pBS608, complete sequence	3903-3931	6	0.793
NC_008595_1	1.18\|279608\|35\|NC_008595\|CRT	279608-279642	35	NZ_CP031166	Euzebya sp. DY32-46 plasmid pEDY32-46I, complete sequence	121883-121917	7	0.8
NC_008595_3	3.1\|2322597\|31\|NC_008595\|CRISPRCasFinder	2322597-2322627	31	NZ_LR134456	Tsukamurella tyrosinosolvens strain NCTC13231 plasmid 14, complete sequence	154500-154530	7	0.774
NC_008595_3	3.1\|2322597\|31\|NC_008595\|CRISPRCasFinder	2322597-2322627	31	NZ_CP029358	Azospirillum sp. CFH 70021 plasmid unnamed3	352345-352375	7	0.774
NC_008595_3	3.1\|2322597\|31\|NC_008595\|CRISPRCasFinder	2322597-2322627	31	NZ_LR594669	Variovorax sp. SRS16 plasmid 4	407323-407353	7	0.774
NC_008595_3	3.1\|2322597\|31\|NC_008595\|CRISPRCasFinder	2322597-2322627	31	NZ_LR594673	Variovorax sp. PBL-E5 plasmid 3	381791-381821	7	0.774
NC_008595_3	3.1\|2322597\|31\|NC_008595\|CRISPRCasFinder	2322597-2322627	31	NC_016586	Azospirillum lipoferum 4B plasmid AZO_p2, complete sequence	75346-75376	7	0.774
NC_008595_7	7.1\|3625457\|29\|NC_008595\|CRISPRCasFinder	3625457-3625485	29	NZ_CP046100	Rhodococcus sp. AQ5-07 plasmid unnamed1, complete sequence	160993-161021	7	0.759
NC_008595_1	1.6\|279605\|38\|NC_008595\|PILER-CR,CRISPRCasFinder	279605-279642	38	NZ_CP011666	Streptomyces sp. Mg1 plasmid pSMg1-2, complete sequence	2919-2956	8	0.789
NC_008595_1	1.6\|279605\|38\|NC_008595\|PILER-CR,CRISPRCasFinder	279605-279642	38	NZ_CP011666	Streptomyces sp. Mg1 plasmid pSMg1-2, complete sequence	129275-129312	8	0.789
NC_008595_1	1.18\|279608\|35\|NC_008595\|CRT	279608-279642	35	NZ_CP027025	Streptomyces sp. WAC00288 plasmid p3, complete sequence	9480-9514	8	0.771
NC_008595_1	1.22\|279854\|34\|NC_008595\|CRT	279854-279887	34	GQ919031	Streptomyces phage ZL12, complete genome	35852-35885	8	0.765
NC_008595_3	3.1\|2322597\|31\|NC_008595\|CRISPRCasFinder	2322597-2322627	31	NC_016113	Streptomyces cattleya NRRL 8057 = DSM 46488 plasmid pSCAT, complete sequence	617924-617954	8	0.742
NC_008595_3	3.1\|2322597\|31\|NC_008595\|CRISPRCasFinder	2322597-2322627	31	NC_017585	Streptomyces cattleya NRRL 8057 = DSM 46488 plasmid pSCATT, complete sequence	1195145-1195175	8	0.742
NC_008595_3	3.1\|2322597\|31\|NC_008595\|CRISPRCasFinder	2322597-2322627	31	NC_016587	Azospirillum lipoferum 4B plasmid AZO_p4, complete sequence	114909-114939	8	0.742
NC_008595_3	3.1\|2322597\|31\|NC_008595\|CRISPRCasFinder	2322597-2322627	31	NZ_CP029833	Azospirillum ramasamyi strain M2T2B2 plasmid unnamed3, complete sequence	347972-348002	8	0.742
NC_008595_3	3.1\|2322597\|31\|NC_008595\|CRISPRCasFinder	2322597-2322627	31	NZ_CP034351	Streptomyces sp. W1SF4 plasmid p1, complete sequence	78885-78915	8	0.742
NC_008595_3	3.1\|2322597\|31\|NC_008595\|CRISPRCasFinder	2322597-2322627	31	NC_013858	Azospirillum sp. B510 plasmid pAB510d, complete sequence	627680-627710	8	0.742
NC_008595_3	3.1\|2322597\|31\|NC_008595\|CRISPRCasFinder	2322597-2322627	31	NZ_CP020333	Martelella mediterranea DSM 17316 strain MACL11 plasmid pMM170, complete sequence	129286-129316	8	0.742
NC_008595_3	3.1\|2322597\|31\|NC_008595\|CRISPRCasFinder	2322597-2322627	31	NZ_CP054617	Azospirillum oryzae strain KACC 14407 plasmid unnamed3, complete sequence	423630-423660	8	0.742
NC_008595_3	3.1\|2322597\|31\|NC_008595\|CRISPRCasFinder	2322597-2322627	31	NZ_CP010957	Sphingobium sp. YBL2 plasmid 3pYBL2-3, complete sequence	23934-23964	8	0.742
NC_008595_3	3.1\|2322597\|31\|NC_008595\|CRISPRCasFinder	2322597-2322627	31	NZ_CP015739	Shinella sp. HZN7 plasmid pShin-03, complete sequence	261069-261099	8	0.742
NC_008595_3	3.1\|2322597\|31\|NC_008595\|CRISPRCasFinder	2322597-2322627	31	NC_015378	Burkholderia gladioli BSR3 plasmid bgla_3p, complete sequence	123169-123199	8	0.742
NC_008595_1	1.10\|279851\|37\|NC_008595\|PILER-CR,CRISPRCasFinder	279851-279887	37	GQ919031	Streptomyces phage ZL12, complete genome	35852-35888	9	0.757
NC_008595_1	1.18\|279608\|35\|NC_008595\|CRT	279608-279642	35	NZ_CP027025	Streptomyces sp. WAC00288 plasmid p3, complete sequence	31350-31384	9	0.743
NC_008595_1	1.18\|279608\|35\|NC_008595\|CRT	279608-279642	35	NZ_CP031166	Euzebya sp. DY32-46 plasmid pEDY32-46I, complete sequence	113131-113165	9	0.743
NC_008595_1	1.18\|279608\|35\|NC_008595\|CRT	279608-279642	35	NC_021056	Streptomyces sp. PAMC 26508 plasmid pSP01, complete sequence	79862-79896	9	0.743
NC_008595_1	1.22\|279854\|34\|NC_008595\|CRT	279854-279887	34	NC_012811	Methylorubrum extorquens AM1 megaplasmid, complete sequence	1107824-1107857	9	0.735
NC_008595_1	1.22\|279854\|34\|NC_008595\|CRT	279854-279887	34	NZ_CP021767	Ralstonia solanacearum strain RS 489 plasmid unnamed, complete sequence	211127-211160	9	0.735
NC_008595_1	1.22\|279854\|34\|NC_008595\|CRT	279854-279887	34	MN908694	Microbacterium phage RubyRalph, complete genome	31532-31565	9	0.735
NC_008595_3	3.1\|2322597\|31\|NC_008595\|CRISPRCasFinder	2322597-2322627	31	NZ_CP022775	Ralstonia solanacearum strain T12 plasmid unnamed, complete sequence	1765139-1765169	9	0.71
NC_008595_3	3.1\|2322597\|31\|NC_008595\|CRISPRCasFinder	2322597-2322627	31	NC_014310	Ralstonia solanacearum PSI07 plasmid mpPSI07, complete sequence	1847934-1847964	9	0.71
NC_008595_3	3.1\|2322597\|31\|NC_008595\|CRISPRCasFinder	2322597-2322627	31	NZ_CP022762	Ralstonia solanacearum strain T95 plasmid unnamed, complete sequence	1687172-1687202	9	0.71
NC_008595_3	3.1\|2322597\|31\|NC_008595\|CRISPRCasFinder	2322597-2322627	31	NZ_CP023017	Ralstonia solanacearum strain SL3022 plasmid unnamed, complete sequence	1757387-1757417	9	0.71
NC_008595_3	3.1\|2322597\|31\|NC_008595\|CRISPRCasFinder	2322597-2322627	31	NZ_CP014703	Ralstonia solanacearum strain KACC 10722 plasmid, complete sequence	1686194-1686224	9	0.71
NC_008595_3	3.1\|2322597\|31\|NC_008595\|CRISPRCasFinder	2322597-2322627	31	NZ_CP022760	Ralstonia solanacearum strain T98 plasmid unnamed, complete sequence	1764137-1764167	9	0.71
NC_008595_3	3.1\|2322597\|31\|NC_008595\|CRISPRCasFinder	2322597-2322627	31	NZ_CP022789	Ralstonia solanacearum strain SL3175 plasmid unnamed, complete sequence	1764138-1764168	9	0.71
NC_008595_3	3.1\|2322597\|31\|NC_008595\|CRISPRCasFinder	2322597-2322627	31	NZ_CP022771	Ralstonia solanacearum strain T51 plasmid unnamed, complete sequence	1687165-1687195	9	0.71
NC_008595_3	3.1\|2322597\|31\|NC_008595\|CRISPRCasFinder	2322597-2322627	31	NZ_CP022777	Ralstonia solanacearum strain T11 plasmid unnamed, complete sequence	1686486-1686516	9	0.71
NC_008595_3	3.1\|2322597\|31\|NC_008595\|CRISPRCasFinder	2322597-2322627	31	NZ_CP022799	Ralstonia solanacearum strain SL2064 plasmid unnamed, complete sequence	1687154-1687184	9	0.71
NC_008595_3	3.1\|2322597\|31\|NC_008595\|CRISPRCasFinder	2322597-2322627	31	NZ_CP022764	Ralstonia solanacearum strain T82 plasmid unnamed, complete sequence	1765312-1765342	9	0.71
NC_008595_3	3.1\|2322597\|31\|NC_008595\|CRISPRCasFinder	2322597-2322627	31	NZ_CP022797	Ralstonia solanacearum strain SL2312 plasmid unnamed, complete sequence	1765310-1765340	9	0.71
NC_008595_3	3.1\|2322597\|31\|NC_008595\|CRISPRCasFinder	2322597-2322627	31	NZ_CP022758	Ralstonia solanacearum strain T101 plasmid unnamed, complete sequence	1765279-1765309	9	0.71
NC_008595_3	3.1\|2322597\|31\|NC_008595\|CRISPRCasFinder	2322597-2322627	31	NZ_CP030074	Streptomyces sp. ZFG47 plasmid unnamed1, complete sequence	790445-790475	9	0.71
NC_008595_3	3.1\|2322597\|31\|NC_008595\|CRISPRCasFinder	2322597-2322627	31	NZ_CP022369	Azospirillum sp. TSH58 plasmid TSH58_p05, complete sequence	77627-77657	9	0.71
NC_008595_3	3.1\|2322597\|31\|NC_008595\|CRISPRCasFinder	2322597-2322627	31	NC_007974	Cupriavidus metallidurans CH34 megaplasmid, complete sequence	990514-990544	9	0.71
NC_008595_3	3.1\|2322597\|31\|NC_008595\|CRISPRCasFinder	2322597-2322627	31	NZ_CP046333	Cupriavidus metallidurans strain FDAARGOS_675 plasmid unnamed3	2356152-2356182	9	0.71
NC_008595_3	3.1\|2322597\|31\|NC_008595\|CRISPRCasFinder	2322597-2322627	31	NZ_CP041045	Paracoccus sp. AK26 plasmid pAK1, complete sequence	225402-225432	9	0.71
NC_008595_1	1.13\|279297\|35\|NC_008595\|CRT	279297-279331	35	NC_018022	Mycolicibacterium chubuense NBB4 plasmid pMYCCH.01, complete sequence	566509-566543	10	0.714
NC_008595_1	1.18\|279608\|35\|NC_008595\|CRT	279608-279642	35	NZ_CP027025	Streptomyces sp. WAC00288 plasmid p3, complete sequence	31826-31860	10	0.714
NC_008595_1	1.22\|279854\|34\|NC_008595\|CRT	279854-279887	34	NZ_CP023408	Streptomyces fungicidicus strain TXX3120 plasmid p1, complete sequence	600282-600315	10	0.706
NC_008595_3	3.1\|2322597\|31\|NC_008595\|CRISPRCasFinder	2322597-2322627	31	NC_016113	Streptomyces cattleya NRRL 8057 = DSM 46488 plasmid pSCAT, complete sequence	326295-326325	10	0.677
NC_008595_3	3.1\|2322597\|31\|NC_008595\|CRISPRCasFinder	2322597-2322627	31	NC_017585	Streptomyces cattleya NRRL 8057 = DSM 46488 plasmid pSCATT, complete sequence	1486772-1486802	10	0.677
NC_008595_3	3.1\|2322597\|31\|NC_008595\|CRISPRCasFinder	2322597-2322627	31	KT381864	Thiobacimonas phage vB_ThpS-P1, complete genome	38274-38304	10	0.677
NC_008595_3	3.1\|2322597\|31\|NC_008595\|CRISPRCasFinder	2322597-2322627	31	NC_011984	Agrobacterium vitis S4 plasmid pAtS4c, complete sequence	146563-146593	10	0.677
NC_008595_3	3.1\|2322597\|31\|NC_008595\|CRISPRCasFinder	2322597-2322627	31	NC_011982	Agrobacterium vitis S4 plasmid pTiS4, complete sequence	88203-88233	10	0.677
NC_008595_3	3.1\|2322597\|31\|NC_008595\|CRISPRCasFinder	2322597-2322627	31	NZ_KY000031	Agrobacterium genomosp. 1 strain Tun198 plasmid pTi_Tun198, complete sequence	16591-16621	10	0.677

1. spacer 4.1|2505654|25|NC_008595|CRISPRCasFinder matches to NZ_AP022607 (Mycobacterium branderi strain JCM 12687 plasmid pJCM12687) position: , mismatch: 3, identity: 0.88

ggccgtgctggccaattcgcggccg	CRISPR spacer
cgccgagctggccaattcgcggcag	Protospacer
 **** ***************** *

2. spacer 4.1|2505654|25|NC_008595|CRISPRCasFinder matches to NZ_CP023738 (Methylosinus trichosporium OB3b plasmid pOB3b1, complete sequence) position: , mismatch: 4, identity: 0.84

ggccgtgctggccaattcgcggccg	CRISPR spacer
ggccgtgctggacaattcgcggtgc	Protospacer
*********** **********.

3. spacer 4.1|2505654|25|NC_008595|CRISPRCasFinder matches to NZ_CP039340 (Ralstonia solanacearum strain UW386 plasmid pUW386, complete sequence) position: , mismatch: 4, identity: 0.84

ggccgtgctggccaattcgcggccg	CRISPR spacer
ggccgcgctggccatttcgcggcga	Protospacer
*****.******** ******** .

4. spacer 8.1|4410402|25|NC_008595|CRISPRCasFinder matches to CP036360 (Agrobacterium sp. 33MFTa1.1 plasmid p_JBx_073812, complete sequence) position: , mismatch: 4, identity: 0.84

gaggaggaggcgggccatcccaccc	CRISPR spacer
gaagaggaggcgggccatcccatag	Protospacer
**.*******************.

5. spacer 1.18|279608|35|NC_008595|CRT matches to NZ_CP011666 (Streptomyces sp. Mg1 plasmid pSMg1-2, complete sequence) position: , mismatch: 5, identity: 0.857

catcccaggtcaggaagtctgctccccgcgtaaga	CRISPR spacer
aatcccagctcaggaagtctgctccccgcgcatgc	Protospacer
 ******* *********************.* *

6. spacer 1.18|279608|35|NC_008595|CRT matches to NZ_CP011666 (Streptomyces sp. Mg1 plasmid pSMg1-2, complete sequence) position: , mismatch: 5, identity: 0.857

catcccaggtcaggaagtctgctccccgcgtaaga	CRISPR spacer
aatcccagctcaggaagtctgctccccgcgcatgc	Protospacer
 ******* *********************.* *

7. spacer 2.1|1474613|28|NC_008595|CRISPRCasFinder matches to NC_016138 (Pseudomonas aeruginosa plasmid pUM505, complete sequence) position: , mismatch: 5, identity: 0.821

cgcgtcgcgacgatgcagagcgcagcga	CRISPR spacer
cacggcgcgacgatgcagagcgcggccg	Protospacer
*.** ******************.** .

8. spacer 2.1|1474613|28|NC_008595|CRISPRCasFinder matches to NC_019202 (Pseudomonas aeruginosa plasmid pKLC102, complete sequence) position: , mismatch: 5, identity: 0.821

cgcgtcgcgacgatgcagagcgcagcga	CRISPR spacer
cacggcgcgacgatgcagagcgcggccg	Protospacer
*.** ******************.** .

9. spacer 2.1|1474613|28|NC_008595|CRISPRCasFinder matches to NZ_CP021032 (Rhizobium sp. NXC14 plasmid pRspNXC14b, complete sequence) position: , mismatch: 5, identity: 0.821

cgcgtcgcgacgatgcagagcgcagcga	CRISPR spacer
catgccgcgatgatgccgagcgcagcga	Protospacer
*..*.*****.***** ***********

10. spacer 2.1|1474613|28|NC_008595|CRISPRCasFinder matches to NZ_CP006990 (Rhizobium sp. IE4771 plasmid pRetIE4771d, complete sequence) position: , mismatch: 5, identity: 0.821

cgcgtcgcgacgatgcagagcgcagcga	CRISPR spacer
ccggccgcgacgatgccgatcgcagcga	Protospacer
*  *.*********** ** ********

11. spacer 6.1|3515422|31|NC_008595|CRISPRCasFinder matches to NZ_CP017941 (Phyllobacterium zundukense strain Tri-48 plasmid unnamed1, complete sequence) position: , mismatch: 5, identity: 0.839

acgcggccaggtccatttgtgtcgcggccgc-	CRISPR spacer
attcggccagttccatctgtgtcgc-gccgct	Protospacer
*. ******* *****.******** *****

12. spacer 2.1|1474613|28|NC_008595|CRISPRCasFinder matches to NZ_CP017077 (Novosphingobium resinovorum strain SA1 plasmid pSA2, complete sequence) position: , mismatch: 6, identity: 0.786

cgcgtcgcgacgatgcagagcgcagcga	CRISPR spacer
acggtcgggacgatgccgagcgcagcgc	Protospacer
   **** ******** **********

13. spacer 2.1|1474613|28|NC_008595|CRISPRCasFinder matches to NZ_CP013104 (Paraburkholderia caribensis strain MWAP64 plasmid 1, complete sequence) position: , mismatch: 6, identity: 0.786

cgcgtcgcgacgatgcagagcgcagcga	CRISPR spacer
acagccgcgacgaggcagtgcgcagcga	Protospacer
   *.******** **** *********

14. spacer 2.1|1474613|28|NC_008595|CRISPRCasFinder matches to NZ_CP012748 (Paraburkholderia caribensis MBA4 plasmid unnamed, complete sequence) position: , mismatch: 6, identity: 0.786

cgcgtcgcgacgatgcagagcgcagcga	CRISPR spacer
acagccgcgacgaggcagtgcgcagcga	Protospacer
   *.******** **** *********

15. spacer 2.1|1474613|28|NC_008595|CRISPRCasFinder matches to NZ_CP018865 (Arthrobacter crystallopoietes strain DSM 20117 plasmid pLDW-10, complete sequence) position: , mismatch: 6, identity: 0.786

-cgcgtcgcgacgatgcagagcgcagcga	CRISPR spacer
ctacggt-cgacgaagcagagcgcagcga	Protospacer
 ..** . ****** **************

16. spacer 2.1|1474613|28|NC_008595|CRISPRCasFinder matches to NZ_CP018865 (Arthrobacter crystallopoietes strain DSM 20117 plasmid pLDW-10, complete sequence) position: , mismatch: 6, identity: 0.786

-cgcgtcgcgacgatgcagagcgcagcga	CRISPR spacer
ctacggt-cgacgaagcagagcgcagcga	Protospacer
 ..** . ****** **************

17. spacer 2.1|1474613|28|NC_008595|CRISPRCasFinder matches to NZ_CP014580 (Burkholderia sp. OLGA172 plasmid pOLGA1, complete sequence) position: , mismatch: 6, identity: 0.786

cgcgtcgcgacgatgcagagcgcagcga	CRISPR spacer
cgcgtcgcgatgatgccgagcgcgtagg	Protospacer
**********.***** ******.  *.

18. spacer 2.1|1474613|28|NC_008595|CRISPRCasFinder matches to MN175604 (Gordonia phage PhorbesPhlower, complete genome) position: , mismatch: 6, identity: 0.786

cgcgtcgcgacgatgcagagcgcagcga	CRISPR spacer
ttcctcgcgacggtgcagaccgcagcgg	Protospacer
. * ********.****** *******.

19. spacer 2.1|1474613|28|NC_008595|CRISPRCasFinder matches to NC_031267 (Gordonia phage Lucky10, complete genome) position: , mismatch: 6, identity: 0.786

cgcgtcgcgacgatgcagagcgcagcga	CRISPR spacer
ttcctcgcgacggtgcagaccgcagcgg	Protospacer
. * ********.****** *******.

20. spacer 7.1|3625457|29|NC_008595|CRISPRCasFinder matches to NZ_CP017765 (Bacillus subtilis strain 29R7-12 plasmid unnamed2, complete sequence) position: , mismatch: 6, identity: 0.793

tgcgccgctcctcctcatcgcttcgctct	CRISPR spacer
agcgccgctgctcctcatcgctcagccca	Protospacer
 ******** ************. **.*

21. spacer 7.1|3625457|29|NC_008595|CRISPRCasFinder matches to NZ_CP017765 (Bacillus subtilis strain 29R7-12 plasmid unnamed2, complete sequence) position: , mismatch: 6, identity: 0.793

tgcgccgctcctcctcatcgcttcgctct	CRISPR spacer
agcgccgctgctcctcatcgctcagccca	Protospacer
 ******** ************. **.*

22. spacer 7.1|3625457|29|NC_008595|CRISPRCasFinder matches to NZ_CP017765 (Bacillus subtilis strain 29R7-12 plasmid unnamed2, complete sequence) position: , mismatch: 6, identity: 0.793

tgcgccgctcctcctcatcgcttcgctct	CRISPR spacer
agcgccgctgctcctcatcgctcagccca	Protospacer
 ******** ************. **.*

23. spacer 7.1|3625457|29|NC_008595|CRISPRCasFinder matches to NC_019849 (Sinorhizobium meliloti GR4 plasmid pRmeGR4d, complete sequence) position: , mismatch: 6, identity: 0.793

tgcgccgctcctcctcatcgcttcgctct	CRISPR spacer
tccgccgcgcctcctcgtcgcttcgggca	Protospacer
* ****** *******.********  *

24. spacer 7.1|3625457|29|NC_008595|CRISPRCasFinder matches to NC_017326 (Sinorhizobium meliloti SM11 plasmid pSmeSM11d, complete sequence) position: , mismatch: 6, identity: 0.793

tgcgccgctcctcctcatcgcttcgctct	CRISPR spacer
tccgccgcgcctcctcgtcgcttcgggca	Protospacer
* ****** *******.********  *

25. spacer 7.1|3625457|29|NC_008595|CRISPRCasFinder matches to NC_017323 (Sinorhizobium meliloti BL225C plasmid pSINMEB02, complete sequence) position: , mismatch: 6, identity: 0.793

tgcgccgctcctcctcatcgcttcgctct	CRISPR spacer
tccgccgcgcctcctcgtcgcttcgggca	Protospacer
* ****** *******.********  *

26. spacer 7.1|3625457|29|NC_008595|CRISPRCasFinder matches to NZ_CP009146 (Sinorhizobium meliloti strain RMO17 plasmid pSymB, complete sequence) position: , mismatch: 6, identity: 0.793

tgcgccgctcctcctcatcgcttcgctct	CRISPR spacer
tccgccgcgcctcctcgtcgcttcgggca	Protospacer
* ****** *******.********  *

27. spacer 7.1|3625457|29|NC_008595|CRISPRCasFinder matches to NC_018701 (Sinorhizobium meliloti Rm41 plasmid pSYMB, complete sequence) position: , mismatch: 6, identity: 0.793

tgcgccgctcctcctcatcgcttcgctct	CRISPR spacer
tccgccgcgcctcctcgtcgcttcgggca	Protospacer
* ****** *******.********  *

28. spacer 7.1|3625457|29|NC_008595|CRISPRCasFinder matches to NZ_CP023428 (Bacillus subtilis strain TLO3 plasmid pBsTLO3, complete sequence) position: , mismatch: 6, identity: 0.793

tgcgccgctcctcctcatcgcttcgctct	CRISPR spacer
agcgccgctgctcctcatcgctcagccca	Protospacer
 ******** ************. **.*

29. spacer 7.1|3625457|29|NC_008595|CRISPRCasFinder matches to NZ_CP021802 (Sinorhizobium meliloti strain USDA1021 plasmid psymB, complete sequence) position: , mismatch: 6, identity: 0.793

tgcgccgctcctcctcatcgcttcgctct	CRISPR spacer
tccgccgcgcctcctcgtcgcttcgggca	Protospacer
* ****** *******.********  *

30. spacer 7.1|3625457|29|NC_008595|CRISPRCasFinder matches to NZ_CP021820 (Sinorhizobium meliloti strain M162 plasmid psymB, complete sequence) position: , mismatch: 6, identity: 0.793

tgcgccgctcctcctcatcgcttcgctct	CRISPR spacer
tccgccgcgcctcctcgtcgcttcgggca	Protospacer
* ****** *******.********  *

31. spacer 7.1|3625457|29|NC_008595|CRISPRCasFinder matches to NZ_CP021831 (Sinorhizobium meliloti strain HM006 plasmid psymB, complete sequence) position: , mismatch: 6, identity: 0.793

tgcgccgctcctcctcatcgcttcgctct	CRISPR spacer
tccgccgcgcctcctcgtcgcttcgggca	Protospacer
* ****** *******.********  *

32. spacer 7.1|3625457|29|NC_008595|CRISPRCasFinder matches to NZ_CP021814 (Sinorhizobium meliloti strain M270 plasmid psymB, complete sequence) position: , mismatch: 6, identity: 0.793

tgcgccgctcctcctcatcgcttcgctct	CRISPR spacer
tccgccgcgcctcctcgtcgcttcgggca	Protospacer
* ****** *******.********  *

33. spacer 7.1|3625457|29|NC_008595|CRISPRCasFinder matches to NZ_CP021810 (Sinorhizobium meliloti strain Rm41 plasmid psymB, complete sequence) position: , mismatch: 6, identity: 0.793

tgcgccgctcctcctcatcgcttcgctct	CRISPR spacer
tccgccgcgcctcctcgtcgcttcgggca	Protospacer
* ****** *******.********  *

34. spacer 7.1|3625457|29|NC_008595|CRISPRCasFinder matches to NZ_CP021218 (Sinorhizobium meliloti RU11/001 plasmid pSymB, complete sequence) position: , mismatch: 6, identity: 0.793

tgcgccgctcctcctcatcgcttcgctct	CRISPR spacer
tccgccgcgcctcctcgtcgcttcgggca	Protospacer
* ****** *******.********  *

35. spacer 7.1|3625457|29|NC_008595|CRISPRCasFinder matches to NZ_CP026527 (Sinorhizobium meliloti strain AK21 plasmid pSymB, complete sequence) position: , mismatch: 6, identity: 0.793

tgcgccgctcctcctcatcgcttcgctct	CRISPR spacer
tccgccgcgcctcctcgtcgcttcgggca	Protospacer
* ****** *******.********  *

36. spacer 7.1|3625457|29|NC_008595|CRISPRCasFinder matches to NZ_CP015223 (Bacillus subtilis strain HRBS-10TDI13 plasmid unnamed, complete sequence) position: , mismatch: 6, identity: 0.793

tgcgccgctcctcctcatcgcttcgctct	CRISPR spacer
agcgccgctgctcctcatcgctcagccca	Protospacer
 ******** ************. **.*

37. spacer 7.1|3625457|29|NC_008595|CRISPRCasFinder matches to NZ_CP021508 (Bacillus subtilis subsp. subtilis strain SRCM101441 plasmid pBL1441-1) position: , mismatch: 6, identity: 0.793

tgcgccgctcctcctcatcgcttcgctct	CRISPR spacer
agcgccgctgctcctcatcgctcagccca	Protospacer
 ******** ************. **.*

38. spacer 7.1|3625457|29|NC_008595|CRISPRCasFinder matches to NC_003078 (Sinorhizobium meliloti 1021 plasmid pSymB, complete sequence) position: , mismatch: 6, identity: 0.793

tgcgccgctcctcctcatcgcttcgctct	CRISPR spacer
tccgccgcgcctcctcgtcgcttcgggca	Protospacer
* ****** *******.********  *

39. spacer 7.1|3625457|29|NC_008595|CRISPRCasFinder matches to NZ_CP019586 (Sinorhizobium meliloti strain CCMM B554 (FSM-MA) plasmid pSymB, complete sequence) position: , mismatch: 6, identity: 0.793

tgcgccgctcctcctcatcgcttcgctct	CRISPR spacer
tccgccgcgcctcctcgtcgcttcgggca	Protospacer
* ****** *******.********  *

40. spacer 7.1|3625457|29|NC_008595|CRISPRCasFinder matches to NZ_CP043503 (Bacillus paralicheniformis strain A4-3 plasmid unnamed2, complete sequence) position: , mismatch: 6, identity: 0.793

tgcgccgctcctcctcatcgcttcgctct	CRISPR spacer
agcgccgctgctcctcatcgctcagccca	Protospacer
 ******** ************. **.*

41. spacer 7.1|3625457|29|NC_008595|CRISPRCasFinder matches to NC_007956 (Bacillus subtilis plasmid pLS30 DNA, complete sequence) position: , mismatch: 6, identity: 0.793

tgcgccgctcctcctcatcgcttcgctct	CRISPR spacer
agcgccgctgctcctcatcgctcagccca	Protospacer
 ******** ************. **.*

42. spacer 7.1|3625457|29|NC_008595|CRISPRCasFinder matches to NZ_CP021799 (Sinorhizobium meliloti strain USDA1106 plasmid psymB, complete sequence) position: , mismatch: 6, identity: 0.793

tgcgccgctcctcctcatcgcttcgctct	CRISPR spacer
tccgccgcgcctcctcgtcgcttcgggca	Protospacer
* ****** *******.********  *

43. spacer 7.1|3625457|29|NC_008595|CRISPRCasFinder matches to NC_001765 (Bacillus subtilis plasmid pTA1015, complete sequence) position: , mismatch: 6, identity: 0.793

tgcgccgctcctcctcatcgcttcgctct	CRISPR spacer
agcgccgctgctcctcatcgctcagccca	Protospacer
 ******** ************. **.*

44. spacer 7.1|3625457|29|NC_008595|CRISPRCasFinder matches to NC_001766 (Bacillus subtilis plasmid pTA1060, complete sequence) position: , mismatch: 6, identity: 0.793

tgcgccgctcctcctcatcgcttcgctct	CRISPR spacer
agcgccgctgctcctcatcgctcagccca	Protospacer
 ******** ************. **.*

45. spacer 7.1|3625457|29|NC_008595|CRISPRCasFinder matches to NZ_CP021828 (Sinorhizobium meliloti strain KH35c plasmid psymB, complete sequence) position: , mismatch: 6, identity: 0.793

tgcgccgctcctcctcatcgcttcgctct	CRISPR spacer
tccgccgcgcctcctcgtcgcttcgggca	Protospacer
* ****** *******.********  *

46. spacer 7.1|3625457|29|NC_008595|CRISPRCasFinder matches to NZ_CP041371 (Bacillus sp. M4U3P1 plasmid unnamed2, complete sequence) position: , mismatch: 6, identity: 0.793

tgcgccgctcctcctcatcgcttcgctct	CRISPR spacer
agcgccgctgctcctcatcgctcagccca	Protospacer
 ******** ************. **.*

47. spacer 7.1|3625457|29|NC_008595|CRISPRCasFinder matches to NC_017194 (Bacillus subtilis subsp. natto BEST195 plasmid pBEST195S, complete sequence) position: , mismatch: 6, identity: 0.793

tgcgccgctcctcctcatcgcttcgctct	CRISPR spacer
agcgccgctgctcctcatcgctcagccca	Protospacer
 ******** ************. **.*

48. spacer 7.1|3625457|29|NC_008595|CRISPRCasFinder matches to NZ_CP021823 (Sinorhizobium meliloti strain KH46 plasmid psymB, complete sequence) position: , mismatch: 6, identity: 0.793

tgcgccgctcctcctcatcgcttcgctct	CRISPR spacer
tccgccgcgcctcctcgtcgcttcgggca	Protospacer
* ****** *******.********  *

49. spacer 7.1|3625457|29|NC_008595|CRISPRCasFinder matches to NZ_CP021795 (Sinorhizobium meliloti strain USDA1157 plasmid psymB, complete sequence) position: , mismatch: 6, identity: 0.793

tgcgccgctcctcctcatcgcttcgctct	CRISPR spacer
tccgccgcgcctcctcgtcgcttcgggca	Protospacer
* ****** *******.********  *

50. spacer 7.1|3625457|29|NC_008595|CRISPRCasFinder matches to NZ_CP021806 (Sinorhizobium meliloti strain T073 plasmid psymB, complete sequence) position: , mismatch: 6, identity: 0.793

tgcgccgctcctcctcatcgcttcgctct	CRISPR spacer
tccgccgcgcctcctcgtcgcttcgggca	Protospacer
* ****** *******.********  *

51. spacer 7.1|3625457|29|NC_008595|CRISPRCasFinder matches to NZ_CP019484 (Sinorhizobium meliloti strain B401 plasmid pSymB, complete sequence) position: , mismatch: 6, identity: 0.793

tgcgccgctcctcctcatcgcttcgctct	CRISPR spacer
tccgccgcgcctcctcgtcgcttcgggca	Protospacer
* ****** *******.********  *

52. spacer 7.1|3625457|29|NC_008595|CRISPRCasFinder matches to NZ_CP014472 (Bacillus subtilis subsp. natto strain CGMCC 2108 plasmid unnamed1, complete sequence) position: , mismatch: 6, identity: 0.793

tgcgccgctcctcctcatcgcttcgctct	CRISPR spacer
agcgccgctgctcctcatcgctcagccca	Protospacer
 ******** ************. **.*

53. spacer 7.1|3625457|29|NC_008595|CRISPRCasFinder matches to NZ_CP019487 (Sinorhizobium meliloti strain B399 plasmid pSym, complete sequence) position: , mismatch: 6, identity: 0.793

tgcgccgctcctcctcatcgcttcgctct	CRISPR spacer
tccgccgcgcctcctcgtcgcttcgggca	Protospacer
* ****** *******.********  *

54. spacer 7.1|3625457|29|NC_008595|CRISPRCasFinder matches to NC_020560 (Sinorhizobium meliloti 2011 plasmid pSymB, complete sequence) position: , mismatch: 6, identity: 0.793

tgcgccgctcctcctcatcgcttcgctct	CRISPR spacer
tccgccgcgcctcctcgtcgcttcgggca	Protospacer
* ****** *******.********  *

55. spacer 7.1|3625457|29|NC_008595|CRISPRCasFinder matches to NC_006825 (Bacillus subtilis plasmid pBS608, complete sequence) position: , mismatch: 6, identity: 0.793

tgcgccgctcctcctcatcgcttcgctct	CRISPR spacer
agcgccgctgctcctcatcgctcagccca	Protospacer
 ******** ************. **.*

56. spacer 1.18|279608|35|NC_008595|CRT matches to NZ_CP031166 (Euzebya sp. DY32-46 plasmid pEDY32-46I, complete sequence) position: , mismatch: 7, identity: 0.8

catcccaggtcaggaagtctgctccccgcgtaaga	CRISPR spacer
aaccgcaggtcaggaagtcttctccccgcgcaggc	Protospacer
 *.* *************** *********.*.*

57. spacer 3.1|2322597|31|NC_008595|CRISPRCasFinder matches to NZ_LR134456 (Tsukamurella tyrosinosolvens strain NCTC13231 plasmid 14, complete sequence) position: , mismatch: 7, identity: 0.774

tggcgacgatgcgggccgggccggcccgagg	CRISPR spacer
tggcgacgatgcgggtcgggccgacggggaa	Protospacer
***************.*******.*  *...

58. spacer 3.1|2322597|31|NC_008595|CRISPRCasFinder matches to NZ_CP029358 (Azospirillum sp. CFH 70021 plasmid unnamed3) position: , mismatch: 7, identity: 0.774

tggcgacgatgcgggccgggccggcccgagg	CRISPR spacer
gctcgacgatgcgggccgcgccggccagcgc	Protospacer
   *************** ******* * *

59. spacer 3.1|2322597|31|NC_008595|CRISPRCasFinder matches to NZ_LR594669 (Variovorax sp. SRS16 plasmid 4) position: , mismatch: 7, identity: 0.774

tggcgacgatgcgggccgggccggcccgagg	CRISPR spacer
ggtcgacgatgcgggccacgccggcctcggg	Protospacer
 * **************. *******. .**

60. spacer 3.1|2322597|31|NC_008595|CRISPRCasFinder matches to NZ_LR594673 (Variovorax sp. PBL-E5 plasmid 3) position: , mismatch: 7, identity: 0.774

tggcgacgatgcgggccgggccggcccgagg	CRISPR spacer
ggtcgacgatgcgggccacgccggcctcggg	Protospacer
 * **************. *******. .**

61. spacer 3.1|2322597|31|NC_008595|CRISPRCasFinder matches to NC_016586 (Azospirillum lipoferum 4B plasmid AZO_p2, complete sequence) position: , mismatch: 7, identity: 0.774

tggcgacgatgcgggccgggccggcccgagg	CRISPR spacer
tggcgacgatgcggcccgcgccgcgctgctg	Protospacer
************** *** ****  *.*  *

62. spacer 7.1|3625457|29|NC_008595|CRISPRCasFinder matches to NZ_CP046100 (Rhodococcus sp. AQ5-07 plasmid unnamed1, complete sequence) position: , mismatch: 7, identity: 0.759

tgcgccgctcctcctcatcgcttcgctct	CRISPR spacer
ggcgccgctcctcctcagcgcgtcggcga	Protospacer
 **************** *** *** .

63. spacer 1.6|279605|38|NC_008595|PILER-CR,CRISPRCasFinder matches to NZ_CP011666 (Streptomyces sp. Mg1 plasmid pSMg1-2, complete sequence) position: , mismatch: 8, identity: 0.789

acccatcccaggtcaggaagtctgctccccgcgtaaga	CRISPR spacer
taaaatcccagctcaggaagtctgctccccgcgcatgc	Protospacer
    ******* *********************.* *

64. spacer 1.6|279605|38|NC_008595|PILER-CR,CRISPRCasFinder matches to NZ_CP011666 (Streptomyces sp. Mg1 plasmid pSMg1-2, complete sequence) position: , mismatch: 8, identity: 0.789

acccatcccaggtcaggaagtctgctccccgcgtaaga	CRISPR spacer
taaaatcccagctcaggaagtctgctccccgcgcatgc	Protospacer
    ******* *********************.* *

65. spacer 1.18|279608|35|NC_008595|CRT matches to NZ_CP027025 (Streptomyces sp. WAC00288 plasmid p3, complete sequence) position: , mismatch: 8, identity: 0.771

catcccaggtcaggaagtctgctccccgcgtaaga	CRISPR spacer
aactgcaggtcaggaagactgctccccgcgtgcgc	Protospacer
 *.. ************ *************. *

66. spacer 1.22|279854|34|NC_008595|CRT matches to GQ919031 (Streptomyces phage ZL12, complete genome) position: , mismatch: 8, identity: 0.765

ggccgcagaggaggccgtcaccgcggcgaagacc	CRISPR spacer
gctggccgaggacgccgtcaccgcggcgaaactc	Protospacer
* . ** ***** *****************. .*

67. spacer 3.1|2322597|31|NC_008595|CRISPRCasFinder matches to NC_016113 (Streptomyces cattleya NRRL 8057 = DSM 46488 plasmid pSCAT, complete sequence) position: , mismatch: 8, identity: 0.742

tggcgacgatgcgggccgggccggcccgagg	CRISPR spacer
cggggacgatgcgggccgcgccggccgcgta	Protospacer
.** ************** *******  . .

68. spacer 3.1|2322597|31|NC_008595|CRISPRCasFinder matches to NC_017585 (Streptomyces cattleya NRRL 8057 = DSM 46488 plasmid pSCATT, complete sequence) position: , mismatch: 8, identity: 0.742

tggcgacgatgcgggccgggccggcccgagg	CRISPR spacer
cggggacgatgcgggccgcgccggccgcgta	Protospacer
.** ************** *******  . .

69. spacer 3.1|2322597|31|NC_008595|CRISPRCasFinder matches to NC_016587 (Azospirillum lipoferum 4B plasmid AZO_p4, complete sequence) position: , mismatch: 8, identity: 0.742

tggcgacgatgcgggccgggccggcccgagg	CRISPR spacer
tgtcggcgatgcgggccgggccggtgctgac	Protospacer
** **.******************. * ..

70. spacer 3.1|2322597|31|NC_008595|CRISPRCasFinder matches to NZ_CP029833 (Azospirillum ramasamyi strain M2T2B2 plasmid unnamed3, complete sequence) position: , mismatch: 8, identity: 0.742

tggcgacgatgcgggccgggccggcccgagg	CRISPR spacer
tgtcggcgatgcgggccgggccggtgctgac	Protospacer
** **.******************. * ..

71. spacer 3.1|2322597|31|NC_008595|CRISPRCasFinder matches to NZ_CP034351 (Streptomyces sp. W1SF4 plasmid p1, complete sequence) position: , mismatch: 8, identity: 0.742

-tggcgacgatgcgggccgggccggcccgagg	CRISPR spacer
atcac-acggtgcgggccgggccggccccgca	Protospacer
 * .* ***.****************** . .

72. spacer 3.1|2322597|31|NC_008595|CRISPRCasFinder matches to NC_013858 (Azospirillum sp. B510 plasmid pAB510d, complete sequence) position: , mismatch: 8, identity: 0.742

tggcgacgatgcgggccgggccggcccgagg	CRISPR spacer
tgtcggcgatgcgggccgggccggtgctgac	Protospacer
** **.******************. * ..

73. spacer 3.1|2322597|31|NC_008595|CRISPRCasFinder matches to NZ_CP020333 (Martelella mediterranea DSM 17316 strain MACL11 plasmid pMM170, complete sequence) position: , mismatch: 8, identity: 0.742

tggcgacgatgcgggccgggccggcccgagg	CRISPR spacer
tggcgatgatgcgggccggggcggtcgatat	Protospacer
******.************* ***.* . .

74. spacer 3.1|2322597|31|NC_008595|CRISPRCasFinder matches to NZ_CP054617 (Azospirillum oryzae strain KACC 14407 plasmid unnamed3, complete sequence) position: , mismatch: 8, identity: 0.742

tggcgacgatgcgggccgggccggcccgagg	CRISPR spacer
tgtcggcgatgcgggccgggccggtgctgac	Protospacer
** **.******************. * ..

75. spacer 3.1|2322597|31|NC_008595|CRISPRCasFinder matches to NZ_CP010957 (Sphingobium sp. YBL2 plasmid 3pYBL2-3, complete sequence) position: , mismatch: 8, identity: 0.742

tggcgacgatgcgggccgggccggcccgagg	CRISPR spacer
ccgcgacgatgcgggccgcggcggcggcatg	Protospacer
. **************** * ****   * *

76. spacer 3.1|2322597|31|NC_008595|CRISPRCasFinder matches to NZ_CP015739 (Shinella sp. HZN7 plasmid pShin-03, complete sequence) position: , mismatch: 8, identity: 0.742

tggcgacgatgcgggccgggccgg----cccgagg	CRISPR spacer
gggcgacgatccgggcccggccggaaaactc----	Protospacer
 ********* ****** ******    *.*

77. spacer 3.1|2322597|31|NC_008595|CRISPRCasFinder matches to NC_015378 (Burkholderia gladioli BSR3 plasmid bgla_3p, complete sequence) position: , mismatch: 8, identity: 0.742

tggcgacgatgcgggccgggccggcccgagg	CRISPR spacer
tcgtgacgttgcgagccgggccggccccgca	Protospacer
* *.**** ****.************* . .

78. spacer 1.10|279851|37|NC_008595|PILER-CR,CRISPRCasFinder matches to GQ919031 (Streptomyces phage ZL12, complete genome) position: , mismatch: 9, identity: 0.757

---accggccgcagaggaggccgtcaccgcggcgaagacc	CRISPR spacer
caagctggcc---gaggacgccgtcaccgcggcgaaactc	Protospacer
   .*.****   ***** *****************. .*

79. spacer 1.18|279608|35|NC_008595|CRT matches to NZ_CP027025 (Streptomyces sp. WAC00288 plasmid p3, complete sequence) position: , mismatch: 9, identity: 0.743

catcccaggtcaggaagtctgctccccgcgtaaga	CRISPR spacer
aactgcaggtcaggaagactgctccccgcgcccgc	Protospacer
 *.. ************ ************.  *

80. spacer 1.18|279608|35|NC_008595|CRT matches to NZ_CP031166 (Euzebya sp. DY32-46 plasmid pEDY32-46I, complete sequence) position: , mismatch: 9, identity: 0.743

catcccaggtcaggaagtctgctccccgcgtaaga	CRISPR spacer
acccgcaggtcaggaagtcttctcccagcgcaggc	Protospacer
  .* *************** ***** ***.*.*

81. spacer 1.18|279608|35|NC_008595|CRT matches to NC_021056 (Streptomyces sp. PAMC 26508 plasmid pSP01, complete sequence) position: , mismatch: 9, identity: 0.743

catcccaggtcaggaagtctgctccccgcgtaaga	CRISPR spacer
aactgcaggtcagtcagtctgctccccgcgcacgc	Protospacer
 *.. ********  ***************.* *

82. spacer 1.22|279854|34|NC_008595|CRT matches to NC_012811 (Methylorubrum extorquens AM1 megaplasmid, complete sequence) position: , mismatch: 9, identity: 0.735

ggccgcagaggaggccgtcaccgcggcgaagacc	CRISPR spacer
gctcgcagaggaggccgtcaccctggcgtttgca	Protospacer
* .******************* .****   .*

83. spacer 1.22|279854|34|NC_008595|CRT matches to NZ_CP021767 (Ralstonia solanacearum strain RS 489 plasmid unnamed, complete sequence) position: , mismatch: 9, identity: 0.735

ggccgcagaggaggccgtcaccgcggcgaagacc	CRISPR spacer
ccgcgaggcggaggctgtcaccggggcgaagacg	Protospacer
   ** .* ******.******* *********

84. spacer 1.22|279854|34|NC_008595|CRT matches to MN908694 (Microbacterium phage RubyRalph, complete genome) position: , mismatch: 9, identity: 0.735

ggccgcagaggaggccgtcaccgcggcgaagacc	CRISPR spacer
cttcccgaacgaggccggcacctcggcgaagacc	Protospacer
  .* *..* ******* **** ***********

85. spacer 3.1|2322597|31|NC_008595|CRISPRCasFinder matches to NZ_CP022775 (Ralstonia solanacearum strain T12 plasmid unnamed, complete sequence) position: , mismatch: 9, identity: 0.71

tggcgacgatgcgggccgggccggcccgagg	CRISPR spacer
gatggacgatgcgggccgggccgaccgcaac	Protospacer
 .  *******************.**  *.

86. spacer 3.1|2322597|31|NC_008595|CRISPRCasFinder matches to NC_014310 (Ralstonia solanacearum PSI07 plasmid mpPSI07, complete sequence) position: , mismatch: 9, identity: 0.71

tggcgacgatgcgggccgggccggcccgagg	CRISPR spacer
gatggacgatgcgggccgggccgaccgcaac	Protospacer
 .  *******************.**  *.

87. spacer 3.1|2322597|31|NC_008595|CRISPRCasFinder matches to NZ_CP022762 (Ralstonia solanacearum strain T95 plasmid unnamed, complete sequence) position: , mismatch: 9, identity: 0.71

tggcgacgatgcgggccgggccggcccgagg	CRISPR spacer
gatggacgatgcgggccgggccgaccgcaac	Protospacer
 .  *******************.**  *.

88. spacer 3.1|2322597|31|NC_008595|CRISPRCasFinder matches to NZ_CP023017 (Ralstonia solanacearum strain SL3022 plasmid unnamed, complete sequence) position: , mismatch: 9, identity: 0.71

tggcgacgatgcgggccgggccggcccgagg	CRISPR spacer
gatggacgatgcgggccgggccgaccgcaac	Protospacer
 .  *******************.**  *.

89. spacer 3.1|2322597|31|NC_008595|CRISPRCasFinder matches to NZ_CP014703 (Ralstonia solanacearum strain KACC 10722 plasmid, complete sequence) position: , mismatch: 9, identity: 0.71

tggcgacgatgcgggccgggccggcccgagg	CRISPR spacer
gatggacgatgcgggccgggccgaccgcaac	Protospacer
 .  *******************.**  *.

90. spacer 3.1|2322597|31|NC_008595|CRISPRCasFinder matches to NZ_CP022760 (Ralstonia solanacearum strain T98 plasmid unnamed, complete sequence) position: , mismatch: 9, identity: 0.71

tggcgacgatgcgggccgggccggcccgagg	CRISPR spacer
gatggacgatgcgggccgggccgaccgcaac	Protospacer
 .  *******************.**  *.

91. spacer 3.1|2322597|31|NC_008595|CRISPRCasFinder matches to NZ_CP022789 (Ralstonia solanacearum strain SL3175 plasmid unnamed, complete sequence) position: , mismatch: 9, identity: 0.71

tggcgacgatgcgggccgggccggcccgagg	CRISPR spacer
gatggacgatgcgggccgggccgaccgcaac	Protospacer
 .  *******************.**  *.

92. spacer 3.1|2322597|31|NC_008595|CRISPRCasFinder matches to NZ_CP022771 (Ralstonia solanacearum strain T51 plasmid unnamed, complete sequence) position: , mismatch: 9, identity: 0.71

tggcgacgatgcgggccgggccggcccgagg	CRISPR spacer
gatggacgatgcgggccgggccgaccgcaac	Protospacer
 .  *******************.**  *.

93. spacer 3.1|2322597|31|NC_008595|CRISPRCasFinder matches to NZ_CP022777 (Ralstonia solanacearum strain T11 plasmid unnamed, complete sequence) position: , mismatch: 9, identity: 0.71

tggcgacgatgcgggccgggccggcccgagg	CRISPR spacer
gatggacgatgcgggccgggccgaccgcaac	Protospacer
 .  *******************.**  *.

94. spacer 3.1|2322597|31|NC_008595|CRISPRCasFinder matches to NZ_CP022799 (Ralstonia solanacearum strain SL2064 plasmid unnamed, complete sequence) position: , mismatch: 9, identity: 0.71

tggcgacgatgcgggccgggccggcccgagg	CRISPR spacer
gatggacgatgcgggccgggccgaccgcaac	Protospacer
 .  *******************.**  *.

95. spacer 3.1|2322597|31|NC_008595|CRISPRCasFinder matches to NZ_CP022764 (Ralstonia solanacearum strain T82 plasmid unnamed, complete sequence) position: , mismatch: 9, identity: 0.71

tggcgacgatgcgggccgggccggcccgagg	CRISPR spacer
gatggacgatgcgggccgggccgaccgcaac	Protospacer
 .  *******************.**  *.

96. spacer 3.1|2322597|31|NC_008595|CRISPRCasFinder matches to NZ_CP022797 (Ralstonia solanacearum strain SL2312 plasmid unnamed, complete sequence) position: , mismatch: 9, identity: 0.71

tggcgacgatgcgggccgggccggcccgagg	CRISPR spacer
gatggacgatgcgggccgggccgaccgcaac	Protospacer
 .  *******************.**  *.

97. spacer 3.1|2322597|31|NC_008595|CRISPRCasFinder matches to NZ_CP022758 (Ralstonia solanacearum strain T101 plasmid unnamed, complete sequence) position: , mismatch: 9, identity: 0.71

tggcgacgatgcgggccgggccggcccgagg	CRISPR spacer
gatggacgatgcgggccgggccgaccgcaac	Protospacer
 .  *******************.**  *.

98. spacer 3.1|2322597|31|NC_008595|CRISPRCasFinder matches to NZ_CP030074 (Streptomyces sp. ZFG47 plasmid unnamed1, complete sequence) position: , mismatch: 9, identity: 0.71

tggcgacgatgcgggccgggccggcccgagg	CRISPR spacer
tcgcgatgatgcgggccgagccggctgtgtt	Protospacer
* ****.***********.******.  .

99. spacer 3.1|2322597|31|NC_008595|CRISPRCasFinder matches to NZ_CP022369 (Azospirillum sp. TSH58 plasmid TSH58_p05, complete sequence) position: , mismatch: 9, identity: 0.71

tggcgacgatgcgggccgggccggcccgagg	CRISPR spacer
tgtcgacgacgcgggccgggccgaattcggc	Protospacer
** ******.*************. .. .*

100. spacer 3.1|2322597|31|NC_008595|CRISPRCasFinder matches to NC_007974 (Cupriavidus metallidurans CH34 megaplasmid, complete sequence) position: , mismatch: 9, identity: 0.71

tggcgacgatgcgggccgggccggcccgagg	CRISPR spacer
tggcgacgatgcgggccgaggcgcgggcgga	Protospacer
******************.* **     .*.

101. spacer 3.1|2322597|31|NC_008595|CRISPRCasFinder matches to NZ_CP046333 (Cupriavidus metallidurans strain FDAARGOS_675 plasmid unnamed3) position: , mismatch: 9, identity: 0.71

tggcgacgatgcgggccgggccggcccgagg	CRISPR spacer
tggcgacgatgcgggccgaggcgcgggcgga	Protospacer
******************.* **     .*.

102. spacer 3.1|2322597|31|NC_008595|CRISPRCasFinder matches to NZ_CP041045 (Paracoccus sp. AK26 plasmid pAK1, complete sequence) position: , mismatch: 9, identity: 0.71

tggcgacgatgcgggccgggccggcccgagg	CRISPR spacer
acccggcgatgcgggccgggccgccctcgga	Protospacer
   **.***************** **. .*.

103. spacer 1.13|279297|35|NC_008595|CRT matches to NC_018022 (Mycolicibacterium chubuense NBB4 plasmid pMYCCH.01, complete sequence) position: , mismatch: 10, identity: 0.714

ggtcggtcactgcggtggtgtcctgtgcatgctcc	CRISPR spacer
ggtcggtcactgcggtgttgacctggtcggtggcg	Protospacer
***************** ** ****  *.    *

104. spacer 1.18|279608|35|NC_008595|CRT matches to NZ_CP027025 (Streptomyces sp. WAC00288 plasmid p3, complete sequence) position: , mismatch: 10, identity: 0.714

catcccaggtcaggaagtctgctccccgcgtaaga	CRISPR spacer
aactgcaggtcagaaagactgctccccgcgcccgc	Protospacer
 *.. ********.*** ************.  *

105. spacer 1.22|279854|34|NC_008595|CRT matches to NZ_CP023408 (Streptomyces fungicidicus strain TXX3120 plasmid p1, complete sequence) position: , mismatch: 10, identity: 0.706

ggccgcagaggaggccgtcaccgcggcgaagacc	CRISPR spacer
cgcgagcgaggcggccgtcaccgcggcgcagcag	Protospacer
 ** .  **** **************** **

106. spacer 3.1|2322597|31|NC_008595|CRISPRCasFinder matches to NC_016113 (Streptomyces cattleya NRRL 8057 = DSM 46488 plasmid pSCAT, complete sequence) position: , mismatch: 10, identity: 0.677

tggcgacgatgcgggccgggccggcccgagg	CRISPR spacer
cctcgacgatgcggtccgcgccggccgcccc	Protospacer
.  *********** *** *******

107. spacer 3.1|2322597|31|NC_008595|CRISPRCasFinder matches to NC_017585 (Streptomyces cattleya NRRL 8057 = DSM 46488 plasmid pSCATT, complete sequence) position: , mismatch: 10, identity: 0.677

tggcgacgatgcgggccgggccggcccgagg	CRISPR spacer
cctcgacgatgcggtccgcgccggccgcccc	Protospacer
.  *********** *** *******

108. spacer 3.1|2322597|31|NC_008595|CRISPRCasFinder matches to KT381864 (Thiobacimonas phage vB_ThpS-P1, complete genome) position: , mismatch: 10, identity: 0.677

tggcgacgatgcgggccgggccggcccgagg	CRISPR spacer
gggcgacgaggcgggccgggccgcgtttcta	Protospacer
 ******** *************  ..   .

109. spacer 3.1|2322597|31|NC_008595|CRISPRCasFinder matches to NC_011984 (Agrobacterium vitis S4 plasmid pAtS4c, complete sequence) position: , mismatch: 10, identity: 0.677

tggcgacgatgcgggccgggccggcccgagg	CRISPR spacer
ccgcggcgatgcgggccggaccggcgatgca	Protospacer
. ***.*************.*****   . .

110. spacer 3.1|2322597|31|NC_008595|CRISPRCasFinder matches to NC_011982 (Agrobacterium vitis S4 plasmid pTiS4, complete sequence) position: , mismatch: 10, identity: 0.677

tggcgacgatgcgggccgggccggcccgagg	CRISPR spacer
ccgcggcgatgcgggccggaccggcgatgca	Protospacer
. ***.*************.*****   . .

111. spacer 3.1|2322597|31|NC_008595|CRISPRCasFinder matches to NZ_KY000031 (Agrobacterium genomosp. 1 strain Tun198 plasmid pTi_Tun198, complete sequence) position: , mismatch: 10, identity: 0.677

tggcgacgatgcgggccgggccggcccgagg	CRISPR spacer
ccgcggcgatgcgggccggaccggcgatgca	Protospacer
. ***.*************.*****   . .

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

0 : 9821

Mycobacterium_phage(33.33%)

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_003874371.1\|2098_3298_+	DNA polymerase III subunit beta	G8I4E4	Mycobacterium_phage	9.8e-69	41.5
WP_011723277.1\|3298_4456_+	DNA replication/repair protein RecF	NA	NA	NA	NA
WP_003874373.1\|4452_4998_+	DUF721 family protein	NA	NA	NA	NA
WP_009974152.1\|5256_7290_+	DNA topoisomerase (ATP-hydrolyzing) subunit B	G3M9Z3	Bacillus_virus	1.1e-133	43.1
WP_011723278.1\|7301_9821_+	DNA gyrase subunit A	A0A172JHV7	Bacillus_phage	1.1e-90	29.6

DBSCAN-SWA_2

13672 : 19842

Bodo_saltans_virus(25.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_009974159.1\|13672_14221_+	peptidylprolyl isomerase	A0A2H4UTF4	Bodo_saltans_virus	1.2e-24	45.2
WP_031348217.1\|14232_14658_-	PH domain-containing protein	NA	NA	NA	NA
WP_003872098.1\|14813_15095_-	cell division protein CrgA	NA	NA	NA	NA
WP_003876787.1\|15225_15969_+	DUF881 domain-containing protein	NA	NA	NA	NA
WP_011723284.1\|16017_16704_+	aminodeoxychorismate/anthranilate synthase component II	A0A0P0IKJ1	Acinetobacter_phage	7.4e-45	47.9
WP_003872101.1\|16681_18562_-	Stk1 family PASTA domain-containing Ser/Thr kinase	A0A2R3ZRI5	Marseillevirus	2.1e-17	31.0
WP_003872102.1\|18558_19842_-	serine/threonine protein kinase	A0A2R8FF19	Brazilian_cedratvirus	2.5e-17	28.9

DBSCAN-SWA_3

33460 : 37480

Corynebacterium_phage(100.0%)

transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_033722227.1\|33460_34693_+\|transposase	IS256-like element IS1245 family transposase	A0A220NQR7	Corynebacterium_phage	1.3e-111	51.3
WP_031349784.1\|34805_36053_-\|transposase	IS256-like element IS1601 family transposase	A0A220NQR7	Corynebacterium_phage	9.8e-80	41.9
WP_011725525.1\|36247_37480_-\|transposase	IS256-like element IS1245 family transposase	A0A220NQR7	Corynebacterium_phage	2.5e-112	51.5

DBSCAN-SWA_4

43146 : 43974

Rhodococcus_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_011723304.1\|43146_43974_+	C40 family peptidase	A0A1W6DXV0	Rhodococcus_phage	7.3e-23	58.7

DBSCAN-SWA_5

53643 : 58606

Staphylococcus_phage(50.0%)

tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_031344725.1\|53643_56553_+\|tRNA	leucine--tRNA ligase	A0A2H4PQS0	Staphylococcus_phage	5.6e-211	44.9
WP_011723314.1\|56559_57231_-	SDR family oxidoreductase	NA	NA	NA	NA
WP_009974218.1\|57289_57793_-	MarR family transcriptional regulator	NA	NA	NA	NA
WP_011723315.1\|57859_58606_-	amino acid ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	1.6e-21	35.1

DBSCAN-SWA_6

67495 : 68602

Stenotrophomonas_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_011723324.1\|67495_68602_-	inositol-3-phosphate synthase	A0A0H4IPK5	Stenotrophomonas_phage	2.1e-73	42.2

DBSCAN-SWA_7

78062 : 80450

Escherichia_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_011723327.1\|78062_80450_+	replicative DNA helicase	G9L681	Escherichia_phage	3.1e-66	28.1

DBSCAN-SWA_8

91194 : 92631

Pandoravirus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_009974267.1\|91194_92631_+	FAD-binding oxidoreductase	S4VRT3	Pandoravirus	3.7e-22	34.5

DBSCAN-SWA_9

97887 : 98454

uncultured_Caudovirales_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_009974289.1\|97887_98454_+	N-acetyltransferase	A0A2H4J136	uncultured_Caudovirales_phage	4.5e-40	53.4

DBSCAN-SWA_10

120840 : 121824

uncultured_Mediterranean_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_031348202.1\|120840_121824_+	2-hydroxyacid dehydrogenase	A0A1B1IVB5	uncultured_Mediterranean_phage	1.5e-14	27.9

DBSCAN-SWA_11

127071 : 127956

Tupanvirus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_011723357.1\|127071_127956_+	class I SAM-dependent methyltransferase	A0A2K9L4K8	Tupanvirus	4.7e-28	31.2

DBSCAN-SWA_12

133688 : 136215

Bacillus_virus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_023862056.1\|133688_134489_+	ABC transporter ATP-binding protein	G3M9Y6	Bacillus_virus	1.1e-28	36.7
WP_011723364.1\|134485_135451_+	aliphatic sulfonate ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_085988234.1\|135483_136215_+	ABC transporter permease	G3M9Y4	Bacillus_virus	2.2e-18	29.2

DBSCAN-SWA_13

140440 : 141769

Feldmannia_species_virus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_011723367.1\|140440_141769_+	HAMP domain-containing histidine kinase	B5LWN0	Feldmannia_species_virus	3.0e-10	26.6

DBSCAN-SWA_14

149837 : 154908

Mycobacterium_phage(100.0%)

protease

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_085989533.1\|149837_151457_+\|protease	type VII secretion system ESX-2 serine protease mycosin MycP2	V5UPA7	Mycobacterium_phage	5.4e-70	36.0
WP_003876914.1\|151453_153040_+	type VII secretion protein EccE	NA	NA	NA	NA
WP_044089838.1\|153069_154908_+	type VII secretion system ESX-2 AAA family ATPase EccA2	V5UQM2	Mycobacterium_phage	1.5e-47	30.1

DBSCAN-SWA_15

167807 : 169010

uncultured_virus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_011723383.1\|167807_169010_-	DNA polymerase IV	A0A218MNF2	uncultured_virus	2.1e-18	33.3

DBSCAN-SWA_16

175682 : 176306

Bacillus_thuringiensis_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_003872294.1\|175682_176306_-	superoxide dismutase [Mn]	Q56AR7	Bacillus_thuringiensis_phage	7.9e-38	43.6

DBSCAN-SWA_17

184725 : 186003

Orpheovirus(100.0%)

tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_009974433.1\|184725_186003_+\|tRNA	serine--tRNA ligase	A0A2I2L4X3	Orpheovirus	1.5e-51	32.6

DBSCAN-SWA_18

198602 : 199811

Streptococcus_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_003876945.1\|198602_199811_+	UDP-galactopyranose mutase	E4ZFQ1	Streptococcus_phage	1.0e-89	44.8

DBSCAN-SWA_19

205513 : 208796

Macacine_betaherpesvirus(66.67%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_011723409.1\|205513_206557_+	esterase family protein	A0A2I6B0H1	Macacine_betaherpesvirus	7.3e-153	81.4
WP_031344666.1\|206718_207621_+	esterase family protein	A0A2I6B2Q9	Macacine_betaherpesvirus	3.1e-43	39.1
WP_003872575.1\|207785_208796_+	cutinase family protein	A0A160DEA1	Gordonia_phage	4.5e-06	27.7

DBSCAN-SWA_20

242545 : 243352

Staphylococcus_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_023862039.1\|242545_243352_-	ABC transporter ATP-binding protein	A0A2H4PQG7	Staphylococcus_phage	4.1e-10	26.5

DBSCAN-SWA_21

252925 : 255593

Pacmanvirus(50.0%)

integrase

attL 246231:246246|attR 258039:258054

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
246231:246246	attL	NA	NA	NA	NA
WP_009974504.1\|252925_253993_-	histidinol-phosphate transaminase	A0A1X6WGT4	Pacmanvirus	1.0e-13	25.4
WP_011723423.1\|254393_255593_-\|integrase	site-specific integrase	G9FGY1	Rhodococcus_phage	1.9e-72	41.7
258039:258054	attR	NA	NA	NA	NA

DBSCAN-SWA_22

273382 : 275530

Erysipelothrix_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_033722258.1\|273382_275530_-	site-specific DNA-methyltransferase	A0A2K5B255	Erysipelothrix_phage	1.0e-15	26.2

DBSCAN-SWA_23

285973 : 286585

Mycobacterium_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_011723457.1\|285973_286585_+	hypothetical protein	A0A1L6BYV6	Mycobacterium_phage	3.9e-05	28.3

DBSCAN-SWA_24

297456 : 306118

Mycobacterium_phage(20.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_003873402.1\|297456_297612_+	hypothetical protein	A0A1C9EH86	Mycobacterium_phage	1.2e-06	54.9
WP_003876976.1\|297723_298428_+	response regulator transcription factor	W8CYM9	Bacillus_phage	1.9e-35	36.4
WP_085989562.1\|298552_299965_+	HAMP domain-containing histidine kinase	Q8QKV7	Ectocarpus_siliculosus_virus	1.2e-09	28.1
WP_003873405.1\|299966_300452_-	lipoprotein LpqH	NA	NA	NA	NA
WP_011723472.1\|300593_302468_+	MBL fold metallo-hydrolase	A0A2P0VMX1	Tetraselmis_virus	1.6e-137	45.7
WP_011723473.1\|302477_303446_-	NADPH:quinone oxidoreductase family protein	NA	NA	NA	NA
WP_010948797.1\|303445_304069_-	TetR/AcrR family transcriptional regulator	NA	NA	NA	NA
WP_011723475.1\|305353_306118_-	glucose 1-dehydrogenase	Q06VL0	Trichoplusia_ni_ascovirus	2.5e-17	31.7

DBSCAN-SWA_25

311083 : 312178

Planktothrix_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_009974532.1\|311083_312178_+	ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	1.2e-20	35.9

DBSCAN-SWA_26

315744 : 320231

Pandoravirus(50.0%)

transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_009974536.1\|315744_316203_+	nucleoside deaminase	S4VYT2	Pandoravirus	2.9e-05	37.1
WP_023862022.1\|316422_317412_+	endo-1,4-beta-glucanase	NA	NA	NA	NA
WP_080516377.1\|317612_317978_+	CAP domain-containing protein	NA	NA	NA	NA
WP_011725525.1\|318998_320231_+\|transposase	IS256-like element IS1245 family transposase	A0A220NQR7	Corynebacterium_phage	2.5e-112	51.5

DBSCAN-SWA_27

328077 : 329316

Hokovirus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_011723490.1\|328077_329316_+	MBL fold metallo-hydrolase	A0A1V0SGC6	Hokovirus	3.6e-26	27.9

DBSCAN-SWA_28

344442 : 345432

uncultured_Mediterranean_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_011723502.1\|344442_345432_+	D-2-hydroxyacid dehydrogenase family protein	A0A1B1IVB5	uncultured_Mediterranean_phage	2.2e-21	25.6

DBSCAN-SWA_29

353272 : 353641

Streptomyces_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_024636789.1\|353272_353641_-	hypothetical protein	A0A2D1GP18	Streptomyces_phage	1.7e-16	49.5

DBSCAN-SWA_30

374304 : 377405

Bacteriophage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_011723521.1\|374304_376131_+	DNA polymerase III subunits gamma/tau	A0A1L2BWV7	Bacteriophage	3.8e-40	31.4
WP_003877009.1\|376142_377405_-	methyltransferase domain-containing protein	A0A2K9L4K8	Tupanvirus	6.1e-37	33.0

DBSCAN-SWA_31

410051 : 410516

Bacillus_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_003873336.1\|410051_410516_+	GatB/YqeY domain-containing protein	A0A218KC79	Bacillus_phage	2.6e-09	35.6

DBSCAN-SWA_32

438368 : 441649

Tsukamurella_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_009974690.1\|438368_438719_+	WhiB family transcriptional regulator	A0A159B6S6	Tsukamurella_phage	3.0e-10	50.0
WP_009974691.1\|438781_439924_-	ArsA family ATPase	NA	NA	NA	NA
WP_003873303.1\|439920_440943_-	ArsA family ATPase	NA	NA	NA	NA
WP_003873302.1\|441010_441172_+	DUF4177 domain-containing protein	NA	NA	NA	NA
WP_011723565.1\|441172_441649_+	RidA family protein	M1I5B0	Acanthocystis_turfacea_Chlorella_virus	8.5e-16	31.5

DBSCAN-SWA_33

446262 : 451890

uncultured_Mediterranean_phage(50.0%)

protease,holin

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_003877060.1\|446262_447456_+\|protease	acid resistance serine protease MarP	A0A1B1IRH0	uncultured_Mediterranean_phage	2.6e-05	25.0
WP_011723569.1\|447448_448414_-	alpha/beta hydrolase	NA	NA	NA	NA
WP_009974700.1\|448414_448954_-\|holin	phage holin family protein	NA	NA	NA	NA
WP_011723570.1\|449174_449846_+	peptidase	NA	NA	NA	NA
WP_011723571.1\|449937_451890_-	acetate--CoA ligase	A0A2H4PQU7	Staphylococcus_phage	5.8e-87	39.4

DBSCAN-SWA_34

456050 : 457697

Planktothrix_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_031348150.1\|456050_457697_+	ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	8.0e-13	28.0

DBSCAN-SWA_35

462701 : 463934

Corynebacterium_phage(100.0%)

transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_011725525.1\|462701_463934_+\|transposase	IS256-like element IS1245 family transposase	A0A220NQR7	Corynebacterium_phage	2.5e-112	51.5

DBSCAN-SWA_36

479393 : 480899

Saudi_moumouvirus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_011723594.1\|479393_480899_+	carboxylesterase family protein	A0A1S5V000	Saudi_moumouvirus	2.1e-31	36.0

DBSCAN-SWA_37

499953 : 505597

Lactococcus_phage(33.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_003419650.1\|499953_500157_+	cold-shock protein	A0A1X9IGI9	Lactococcus_phage	2.0e-14	56.2
WP_011723615.1\|500345_500936_+	hypothetical protein	NA	NA	NA	NA
WP_009974717.1\|501140_503939_+	type I DNA topoisomerase	A0A2K9L5F8	Tupanvirus	8.6e-100	30.7
WP_010948854.1\|503935_505597_-	adenylate/guanylate cyclase domain-containing protein	A0A1B1IWY2	uncultured_Mediterranean_phage	8.4e-18	32.8

DBSCAN-SWA_38

508881 : 513830

Tupanvirus(33.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_011723619.1\|508881_509823_+	NAD-dependent epimerase/dehydratase family protein	A0A2K9L0I7	Tupanvirus	4.1e-38	35.1
WP_003873266.1\|509819_510161_-	DUF2304 domain-containing protein	NA	NA	NA	NA
WP_003873265.1\|510157_510859_-	glycosyltransferase family 2 protein	NA	NA	NA	NA
WP_009974726.1\|510894_512145_-	hypothetical protein	NA	NA	NA	NA
WP_011723621.1\|512272_513361_+	DUF475 domain-containing protein	A0A172Q0Y5	Acinetobacter_phage	2.4e-53	41.3
WP_009974729.1\|513341_513830_-	inorganic diphosphatase	A0A2H4J8U1	uncultured_Caudovirales_phage	7.3e-31	45.1

DBSCAN-SWA_39

517353 : 520658

Hokovirus(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_085988233.1\|517353_518010_+	hypoxanthine phosphoribosyltransferase	A0A1V0SEQ1	Hokovirus	2.2e-06	26.4
WP_011723624.1\|518017_518767_-	DUF541 domain-containing protein	NA	NA	NA	NA
WP_011723625.1\|519083_519383_+	PE family protein	NA	NA	NA	NA
WP_011723626.1\|519392_520658_+	PPE family protein	V5UPR1	Mycobacterium_phage	4.6e-08	32.5

DBSCAN-SWA_40

526344 : 530198

Bathycoccus_sp._RCC1105_virus(33.33%)

protease

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_011723630.1\|526344_528744_+\|protease	ATP-dependent zinc metalloprotease FtsH	E5EQU5	Bathycoccus_sp._RCC1105_virus	4.3e-108	44.9
WP_011723631.1\|528760_529375_+	GTP cyclohydrolase I FolE	E7DN69	Pneumococcus_phage	2.5e-44	53.4
WP_033713005.1\|529394_530198_+	dihydropteroate synthase	S4W084	Pandoravirus	3.0e-21	33.0

DBSCAN-SWA_41

536334 : 541184

Tupanvirus(33.33%)

protease,tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_009974742.1\|536334_537834_+\|tRNA	lysine--tRNA ligase	A0A2K9KZX5	Tupanvirus	4.4e-74	36.6
WP_003875617.1\|537977_538316_+	Lsr2 family protein	A0A2D1GPL8	Mycobacterium_phage	2.1e-16	41.5
WP_019684762.1\|538652_541184_+\|protease	ATP-dependent Clp protease ATP-binding subunit	K4FB40	Cronobacter_phage	1.0e-128	39.7

DBSCAN-SWA_42

554658 : 557936

Catovirus(50.0%)

tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_009974759.1\|554658_556065_+\|tRNA	cysteine--tRNA ligase	A0A1V0SAQ2	Catovirus	8.3e-43	26.2
WP_009974760.1\|556065_556995_+	23S rRNA (guanosine(2251)-2'-O)-methyltransferase RlmB	NA	NA	NA	NA
WP_033712983.1\|557042_557936_+	glycerophosphodiester phosphodiesterase	M1HHE5	Acanthocystis_turfacea_Chlorella_virus	9.1e-11	25.2

DBSCAN-SWA_43

562081 : 566700

uncultured_Caudovirales_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_011723650.1\|562081_563323_-	arsenic transporter	A0A2H4J144	uncultured_Caudovirales_phage	2.0e-16	27.5
WP_085989567.1\|563333_564197_-	MBL fold metallo-hydrolase	NA	NA	NA	NA
WP_011723652.1\|564250_565009_-	LamB/YcsF family protein	NA	NA	NA	NA
WP_011723653.1\|565018_565879_-	metal ABC transporter permease	NA	NA	NA	NA
WP_011723654.1\|565878_566700_-	metal ABC transporter ATP-binding protein	W5SAS9	Pithovirus	1.9e-07	24.4

DBSCAN-SWA_44

583952 : 585482

Hepacivirus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_011723664.1\|583952_585482_-	fatty acid--CoA ligase family protein	Q75ZG1	Hepacivirus	8.5e-41	27.6

DBSCAN-SWA_45

595259 : 596165

Trichoplusia_ni_ascovirus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_011723666.1\|595259_596165_+	SDR family oxidoreductase	Q06VL0	Trichoplusia_ni_ascovirus	5.0e-09	27.7

DBSCAN-SWA_46

608997 : 609912

Ostreococcus_lucimarinus_virus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_009974801.1\|608997_609912_+	acetaldehyde dehydrogenase (acetylating)	G9E526	Ostreococcus_lucimarinus_virus	2.6e-37	33.1

DBSCAN-SWA_47

625684 : 630499

Staphylococcus_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_011723680.1\|625684_627325_+	acyl-CoA synthetase	A0A2H4PQM9	Staphylococcus_phage	7.0e-17	24.0
WP_009974821.1\|627334_628102_+	phosphotransferase	NA	NA	NA	NA
WP_011723681.1\|628124_628952_+	amidohydrolase	NA	NA	NA	NA
WP_011723682.1\|628948_630499_+	acetolactate synthase large subunit	E5EQ70	Micromonas_sp._RCC1109_virus	1.9e-08	31.1

DBSCAN-SWA_48

649970 : 650672

Planktothrix_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_099156407.1\|649970_650672_+	phosphate ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	1.2e-13	33.2

DBSCAN-SWA_49

663484 : 665344

Chrysochromulina_ericina_virus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_024637627.1\|663484_665344_+	hypothetical protein	A0A0N9QAZ1	Chrysochromulina_ericina_virus	5.0e-19	27.5

DBSCAN-SWA_50

673525 : 683363

Bacillus_phage(33.33%)

integrase

attL 665426:665471|attR 675801:675846

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
665426:665471	attL	NA	NA	NA	NA
WP_011723711.1\|673525_673723_-	helix-turn-helix domain-containing protein	A0A2D1GF53	Mycobacterium_phage	6.6e-07	50.0
WP_141119152.1\|673860_674538_+	hypothetical protein	NA	NA	NA	NA
WP_033722361.1\|674540_675725_+\|integrase	site-specific integrase	G9FGY1	Rhodococcus_phage	1.6e-71	42.6
WP_003875751.1\|675902_676619_-	hypothetical protein	NA	NA	NA	NA
675801:675846	attR	NA	NA	NA	NA
WP_003875752.1\|676778_677498_+	response regulator transcription factor	W8CYM9	Bacillus_phage	1.4e-33	35.9
WP_011723714.1\|677538_678975_+	HAMP domain-containing histidine kinase	W8CYF6	Bacillus_phage	7.0e-21	29.5
WP_011723715.1\|678962_679367_-	HIT family protein	NA	NA	NA	NA
WP_003875755.1\|679401_679824_-	NTF2 domain-containing protein	NA	NA	NA	NA
WP_003875756.1\|679893_681021_-	NDMA-dependent alcohol dehydrogenase	E3SJ82	Synechococcus_phage	7.1e-29	27.6
WP_003875757.1\|681233_681782_-	hypothetical protein	NA	NA	NA	NA
WP_003875758.1\|681785_681995_-	ferredoxin	NA	NA	NA	NA
WP_009974879.1\|682007_683363_-	cytochrome P450	M1PWN0	Moumouvirus	7.3e-12	27.4

DBSCAN-SWA_51

698612 : 701662

Mollivirus(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_009974902.1\|698612_699503_+	phosphoribosylaminoimidazolesuccinocarboxamide synthase	A0A0M4JBD3	Mollivirus	6.4e-41	36.4
WP_011723721.1\|699499_701662_+	S9 family peptidase	A0A1V0SHT0	Klosneuvirus	9.5e-30	29.4

DBSCAN-SWA_52

716781 : 722970

Microbacterium_phage(33.33%)

protease

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_011723730.1\|716781_719079_+	phosphoribosylformylglycinamidine synthase subunit PurL	A6N228	Microbacterium_phage	2.1e-269	62.8
WP_011723731.1\|719098_719749_+\|protease	CPBP family intramembrane metalloprotease	NA	NA	NA	NA
WP_011723732.1\|719761_720151_+	hypothetical protein	NA	NA	NA	NA
WP_085978605.1\|720216_721815_+	amidophosphoribosyltransferase	A0A1B1ISH6	uncultured_Mediterranean_phage	1.2e-45	29.7
WP_003877203.1\|721875_722970_+	phosphoribosylformylglycinamidine cyclo-ligase	Q58MH8	Prochlorococcus_phage	1.0e-56	37.9

DBSCAN-SWA_53

731019 : 731802

Bacillus_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_003875810.1\|731019_731802_+	response regulator transcription factor	W8CYM9	Bacillus_phage	9.1e-15	32.5

DBSCAN-SWA_54

736055 : 736832

Planktothrix_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_003875815.1\|736055_736832_+	phosphate ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	2.8e-16	33.7

DBSCAN-SWA_55

744435 : 764631

Mycobacterium_phage(76.92%)

integrase

attL 732092:732110|attR 754032:754050

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
732092:732110	attL	NA	NA	NA	NA
WP_024636831.1\|744435_744837_-	helix-turn-helix transcriptional regulator	E4ZFI8	Streptococcus_phage	4.6e-07	31.9
WP_003875824.1\|744880_745414_-	nucleoside deaminase	S4VYZ2	Pandoravirus	1.1e-14	37.9
WP_011723749.1\|745459_746356_+	class I SAM-dependent methyltransferase	NA	NA	NA	NA
WP_049770245.1\|746827_747421_+\|integrase	tyrosine-type recombinase/integrase	W8EHC2	Mycobacterium_phage	6.3e-85	76.8
WP_080516332.1\|747398_747791_+	DUF732 domain-containing protein	NA	NA	NA	NA
WP_011723752.1\|747787_748441_+	hypothetical protein	NA	NA	NA	NA
WP_049770246.1\|748549_749059_-	hypothetical protein	NA	NA	NA	NA
WP_003921239.1\|749055_749328_-	hypothetical protein	NA	NA	NA	NA
WP_003921242.1\|749632_750574_-	cutinase family protein	S5XW61	Mycobacterium_phage	6.6e-36	37.2
WP_011723754.1\|750570_751947_-	hypothetical protein	A0A068F1N1	Mycobacterium_phage	1.1e-36	42.4
WP_011723755.1\|751943_752360_-	hypothetical protein	NA	NA	NA	NA
WP_080516333.1\|753227_754304_-	PPE family protein	NA	NA	NA	NA
754032:754050	attR	NA	NA	NA	NA
WP_011723758.1\|754308_756006_-	hypothetical protein	A0A0M4RBJ6	Mycobacterium_phage	5.7e-06	36.8
WP_011723759.1\|756007_756397_-	hypothetical protein	A0A0M4R233	Mycobacterium_phage	5.0e-14	39.7
WP_155267850.1\|756407_756806_-	hypothetical protein	R4JHR0	Mycobacterium_phage	6.4e-25	47.5
WP_011723761.1\|756885_758385_-	hypothetical protein	G1BSP9	Mycobacterium_virus	2.0e-10	35.7
WP_011723762.1\|758532_758844_-	hypothetical protein	NA	NA	NA	NA
WP_011723763.1\|758847_760443_-	hypothetical protein	Q9ZX54	Mycobacterium_phage	1.3e-12	27.1
WP_011723764.1\|760439_761345_-	hypothetical protein	S5Y2N9	Mycobacterium_phage	4.7e-31	38.7
WP_011723765.1\|761341_763078_-	hypothetical protein	S5Y0P6	Mycobacterium_phage	1.5e-118	40.2
WP_033722373.1\|763074_764631_-	hypothetical protein	A0A0K1Y6N2	Mycobacterium_phage	1.3e-60	31.3

DBSCAN-SWA_56

770060 : 780270

Mycobacterium_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_011723769.1\|770060_770546_-	hypothetical protein	A0A0A1ENX3	Mycobacterium_phage	2.7e-25	42.5
WP_011723770.1\|770633_771680_-	hypothetical protein	A0A2D1GAJ8	Mycobacterium_phage	2.8e-35	35.7
WP_011723771.1\|771752_772175_-	hypothetical protein	NA	NA	NA	NA
WP_011723772.1\|772171_772693_-	hypothetical protein	NA	NA	NA	NA
WP_011723773.1\|772787_773225_-	hypothetical protein	NA	NA	NA	NA
WP_011723774.1\|773217_773700_-	hypothetical protein	NA	NA	NA	NA
WP_011723775.1\|773701_774034_-	hypothetical protein	A0A1D8EWY7	Mycobacterium_phage	4.4e-11	38.3
WP_011723776.1\|774033_775071_-	hypothetical protein	A0A1D8EWX7	Mycobacterium_phage	4.7e-67	43.8
WP_011723777.1\|775179_775578_-	DUF2190 family protein	A0A142K8P7	Gordonia_phage	5.3e-11	37.4
WP_155267851.1\|775579_776857_-	hypothetical protein	A0A142K9Z2	Gordonia_phage	1.7e-47	33.3
WP_155267852.1\|778409_779960_-	hypothetical protein	A0A142KC08	Gordonia_phage	3.9e-134	54.7
WP_011723781.1\|779910_780270_-	hypothetical protein	A0A0U4K3Z3	Gordonia_phage	1.3e-05	37.8

DBSCAN-SWA_57

783607 : 784884

Mycobacterium_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_011723789.1\|783607_783976_-	hypothetical protein	H6WSI1	Mycobacterium_phage	1.7e-27	54.2
WP_011723790.1\|783972_784884_-	hypothetical protein	A0A097EYS9	Mycobacterium_phage	4.5e-58	51.0

DBSCAN-SWA_58

788197 : 793434

Mycobacterium_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_011723795.1\|788197_789310_-	recombination protein RecT	M4WNV2	Mycobacterium_phage	7.9e-105	57.1
WP_155267856.1\|789325_790162_-	hypothetical protein	A0A142UN41	Mycobacterium_phage	2.3e-64	46.9
WP_011723798.1\|790297_790558_-	hypothetical protein	A0A2H4PFT2	Mycobacterium_phage	1.3e-15	52.6
WP_155267854.1\|790656_790812_-	hypothetical protein	NA	NA	NA	NA
WP_033710557.1\|790939_791254_-	hypothetical protein	NA	NA	NA	NA
WP_003921311.1\|791317_791605_-	hypothetical protein	NA	NA	NA	NA
WP_011723801.1\|791750_792539_-	phage antirepressor KilAC domain-containing protein	E0YQ36	Mycobacterium_phage	1.4e-76	58.1
WP_011723803.1\|792642_793434_-	phage antirepressor KilAC domain-containing protein	A0A2D1G9T5	Mycobacterium_phage	1.7e-61	49.8

DBSCAN-SWA_59

798979 : 799183

Lactococcus_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_003873070.1\|798979_799183_+	cold-shock protein	Q9AZD3	Lactococcus_phage	1.5e-17	63.1

DBSCAN-SWA_60

807548 : 809415

Synechococcus_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_003877228.1\|807548_807887_-	2Fe-2S iron-sulfur cluster binding domain-containing protein	A0A222YX16	Synechococcus_phage	3.3e-06	28.9
WP_011723812.1\|808011_809415_+	AMP-binding protein	Q75ZG1	Hepacivirus	2.4e-34	27.5

DBSCAN-SWA_61

819231 : 820848

Lactobacillus_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_011723821.1\|819231_820848_-	FAD-dependent oxidoreductase	A0A2P0ZL82	Lactobacillus_phage	3.0e-28	28.3

DBSCAN-SWA_62

825131 : 826859

Lactobacillus_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_011723823.1\|825131_826859_+	FAD-binding protein	A0A2P0ZL82	Lactobacillus_phage	1.2e-19	23.9

DBSCAN-SWA_63

832657 : 833464

Trichoplusia_ni_ascovirus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_011723827.1\|832657_833464_+	SDR family oxidoreductase	Q06VL0	Trichoplusia_ni_ascovirus	9.0e-18	31.9

DBSCAN-SWA_64

883972 : 884674

Escherichia_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_003877305.1\|883972_884674_-	SDR family oxidoreductase	I7B2R4	Escherichia_phage	3.8e-12	34.1

DBSCAN-SWA_65

908601 : 912578

Tupanvirus(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_011723867.1\|908601_910077_+	fatty acid--CoA ligase family protein	A0A2K9KZV5	Tupanvirus	2.6e-15	21.4
WP_011723868.1\|910073_910700_+	hypothetical protein	NA	NA	NA	NA
WP_003872942.1\|910710_910896_+	(2Fe-2S)-binding protein	NA	NA	NA	NA
WP_011723869.1\|910892_912578_-	alpha-keto acid decarboxylase family protein	A0A0P0CDR3	Ostreococcus_lucimarinus_virus	5.7e-06	21.6

DBSCAN-SWA_66

926755 : 928405

Acidianus_filamentous_virus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_009975114.1\|926755_928405_-	DEAD/DEAH box helicase	B2CRJ8	Acidianus_filamentous_virus	4.1e-17	23.1

DBSCAN-SWA_67

932552 : 936111

Macacine_betaherpesvirus(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_029248386.1\|932552_933326_-	transglycosylase family protein	A0A2I6B0Z0	Macacine_betaherpesvirus	2.4e-04	71.0
WP_011723885.1\|933759_934038_-	MoaD/ThiS family protein	NA	NA	NA	NA
WP_009975124.1\|935132_935540_-	YccF domain-containing protein	NA	NA	NA	NA
WP_003872914.1\|935703_936111_+	cold-shock protein	Q9AZD3	Lactococcus_phage	1.3e-09	46.0

DBSCAN-SWA_68

969048 : 971421

Paramecium_bursaria_Chlorella_virus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_011723900.1\|969048_971421_+	cation-translocating P-type ATPase	M1HX51	Paramecium_bursaria_Chlorella_virus	1.4e-29	26.6

DBSCAN-SWA_69

986286 : 987195

Mycobacterium_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_009975180.1\|986286_987195_-	Ku protein	A0A249XRB2	Mycobacterium_phage	6.9e-67	50.4

DBSCAN-SWA_70

990534 : 994607

Micromonas_sp._RCC1109_virus(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_033720318.1\|990534_992028_-	mannitol dehydrogenase family protein	E5EQS6	Micromonas_sp._RCC1109_virus	4.2e-53	32.0
WP_011723912.1\|992306_994607_+	ATP-dependent DNA ligase	A0A291AUP8	Sinorhizobium_phage	7.7e-38	36.1

DBSCAN-SWA_71

1008923 : 1015368

Bacillus_phage(33.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_011723921.1\|1008923_1011248_+	DNA helicase PcrA	A7KV33	Bacillus_phage	4.5e-118	37.2
WP_003872834.1\|1011321_1011912_-	hypothetical protein	NA	NA	NA	NA
WP_011723922.1\|1011913_1012966_-	M23 family metallopeptidase	A0A2D1G842	Mycobacterium_phage	1.5e-20	48.8
WP_003872832.1\|1013289_1014453_+	ADP-forming succinate--CoA ligase subunit beta	NA	NA	NA	NA
WP_011723923.1\|1014465_1015368_+	succinate--CoA ligase subunit alpha	A0A2K9L5E9	Tupanvirus	1.2e-13	28.7

DBSCAN-SWA_72

1020669 : 1022897

Synechococcus_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_003872825.1\|1020669_1021299_+	phosphoribosylglycinamide formyltransferase	M4QRX9	Synechococcus_phage	7.5e-20	34.3
WP_024636987.1\|1021313_1022897_+	bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase	Q58MG4	Prochlorococcus_phage	1.8e-54	42.3

DBSCAN-SWA_73

1027181 : 1028030

Staphylococcus_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_011723931.1\|1027181_1028030_+	aldo/keto reductase	A0A2H4PQR8	Staphylococcus_phage	6.1e-57	39.9

DBSCAN-SWA_74

1037760 : 1045439

Bacillus_phage(75.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_003872811.1\|1037760_1038447_+	response regulator transcription factor	W8CYM9	Bacillus_phage	4.8e-36	38.3
WP_019732008.1\|1038463_1040032_+	HAMP domain-containing histidine kinase	W8CYF6	Bacillus_phage	1.1e-19	28.3
WP_011723940.1\|1040114_1041581_+	PDZ domain-containing protein	A0A1B1IRD3	uncultured_Mediterranean_phage	5.5e-05	32.5
WP_008254072.1\|1041640_1042138_+	MogA/MoaB family molybdenum cofactor biosynthesis protein	NA	NA	NA	NA
WP_003872807.1\|1042162_1042618_-	large-conductance mechanosensitive channel protein MscL	NA	NA	NA	NA
WP_011723941.1\|1042685_1043366_-	hypothetical protein	NA	NA	NA	NA
WP_003872805.1\|1043430_1043757_-	FmdB family transcriptional regulator	NA	NA	NA	NA
WP_011723942.1\|1043863_1044454_-	5-formyltetrahydrofolate cyclo-ligase	NA	NA	NA	NA
WP_003877502.1\|1044530_1045439_+	UTP--glucose-1-phosphate uridylyltransferase	A0A127AW70	Bacillus_phage	2.3e-46	40.1

DBSCAN-SWA_75

1056775 : 1058397

Synechococcus_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_003877509.1\|1056775_1057792_+	GHMP kinase	A0A222YW25	Synechococcus_phage	2.3e-55	39.1
WP_009975259.1\|1057788_1058397_+	SIS domain-containing protein	A0A067XQR2	Caulobacter_phage	7.8e-14	33.3

DBSCAN-SWA_76

1061680 : 1062298

Pacmanvirus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_009975264.1\|1061680_1062298_-	alpha-ketoglutarate-dependent dioxygenase AlkB	A0A1X6WG33	Pacmanvirus	7.7e-09	29.4

DBSCAN-SWA_77

1066108 : 1067359

Pandoravirus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_009975267.1\|1066108_1067359_-	aminodeoxychorismate synthase component I	S4VT78	Pandoravirus	1.8e-36	41.7

DBSCAN-SWA_78

1073514 : 1074309

Ostreococcus_tauri_virus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_011723960.1\|1073514_1074309_-	FkbM family methyltransferase	E4WLN6	Ostreococcus_tauri_virus	8.3e-08	34.7

DBSCAN-SWA_79

1087531 : 1091255

Hokovirus(50.0%)

tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_011723967.1\|1087531_1089091_-\|tRNA	methionine--tRNA ligase	A0A1V0SEZ7	Hokovirus	1.8e-102	40.0
WP_011723968.1\|1089110_1089965_+	TatD family hydrolase	NA	NA	NA	NA
WP_019732437.1\|1090166_1091255_+	resuscitation-promoting factor	A0A1I9SA30	Rhodococcus_phage	9.0e-21	63.5

DBSCAN-SWA_80

1098217 : 1099546

uncultured_Caudovirales_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_009975291.1\|1098217_1098565_-	arsenate reductase (glutaredoxin)	A0A2H4J8T1	uncultured_Caudovirales_phage	1.4e-31	60.7
WP_003877535.1\|1098565_1099546_-	ribose-phosphate diphosphokinase	A0A2K9L2G2	Tupanvirus	8.1e-45	36.4

DBSCAN-SWA_81

1109423 : 1114123

Streptococcus_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_003877542.1\|1109423_1110713_+	phosphopyruvate hydratase	W6LP63	Streptococcus_phage	8.5e-135	56.9
WP_011723977.1\|1110714_1111392_+	septum formation initiator family protein	NA	NA	NA	NA
WP_003872730.1\|1111384_1111873_+	DUF501 domain-containing protein	NA	NA	NA	NA
WP_019732886.1\|1111866_1112817_+	Ppx/GppA family phosphatase	NA	NA	NA	NA
WP_003872728.1\|1113046_1113355_+	hypothetical protein	NA	NA	NA	NA
WP_003877545.1\|1113442_1114123_-	response regulator	W8CYM9	Bacillus_phage	3.8e-25	30.5

DBSCAN-SWA_82

1117638 : 1119789

Paramecium_bursaria_Chlorella_virus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_011723981.1\|1117638_1119789_-	potassium-transporting ATPase subunit KdpB	M1HBF8	Paramecium_bursaria_Chlorella_virus	4.0e-28	25.1

DBSCAN-SWA_83

1123354 : 1124128

Bacillus_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_009975275.1\|1123354_1124128_-	response regulator transcription factor	W8CYM9	Bacillus_phage	3.3e-33	35.6

DBSCAN-SWA_84

1132523 : 1134155

Catovirus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_011723988.1\|1132523_1134155_+	fatty acid--CoA ligase	A0A1V0SBX8	Catovirus	2.8e-18	25.0

DBSCAN-SWA_85

1147808 : 1151229

Streptococcus_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_003872698.1\|1147808_1149215_+	cystathionine beta-synthase	A0A1X9I5F1	Streptococcus_phage	5.0e-56	41.4
WP_011723999.1\|1149305_1150025_+	RDD family protein	NA	NA	NA	NA
WP_003872696.1\|1150062_1151229_+	cystathionine gamma-synthase	A0A0B5JD48	Pandoravirus	1.1e-24	31.2

DBSCAN-SWA_86

1157056 : 1157845

Flavobacterium_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_003878551.1\|1157056_1157845_+	isoprenyl transferase	R9W0U9	Flavobacterium_phage	5.4e-15	36.7

DBSCAN-SWA_87

1161027 : 1167245

Aeromonas_phage(33.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_031348075.1\|1161027_1162308_+	serine hydroxymethyltransferase	A0A240F3L3	Aeromonas_phage	2.9e-87	48.8
WP_011724007.1\|1162395_1163223_+	acyl-ACP desaturase	NA	NA	NA	NA
WP_009975376.1\|1163442_1164744_+	PhoH family protein	A0A2L0UZX2	Agrobacterium_phage	2.3e-23	30.8
WP_011724008.1\|1164871_1165747_+	polysaccharide deacetylase family protein	NA	NA	NA	NA
WP_011724009.1\|1165811_1167245_+	adenylate/guanylate cyclase domain-containing protein	A0A1B1IWY2	uncultured_Mediterranean_phage	1.3e-14	29.2

DBSCAN-SWA_88

1172472 : 1176661

Moumouvirus(33.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_011724013.1\|1172472_1174017_+	carboxylesterase/lipase family protein	M1PNU1	Moumouvirus	1.5e-32	35.2
WP_009975382.1\|1174013_1175114_-	NAD-dependent epimerase/dehydratase family protein	Q76TT0	Molluscum_contagiosum_virus	2.4e-29	33.0
WP_003875383.1\|1175175_1175424_-	exodeoxyribonuclease VII small subunit	NA	NA	NA	NA
WP_009975385.1\|1175413_1176661_-	exodeoxyribonuclease VII large subunit	A0A1B3AYB4	Gordonia_phage	4.0e-73	52.6

DBSCAN-SWA_89

1182283 : 1197744

Corynebacterium_phage(25.0%)

transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_011725525.1\|1182283_1183516_+\|transposase	IS256-like element IS1245 family transposase	A0A220NQR7	Corynebacterium_phage	2.5e-112	51.5
WP_011724019.1\|1184294_1185599_-\|transposase	IS256-like element IS666 family transposase	A0A2P1JQX9	Mycobacterium_phage	2.1e-210	83.4
WP_050484363.1\|1185707_1186928_-\|transposase	IS256 family transposase	A0A220NQR7	Corynebacterium_phage	3.6e-111	53.0
WP_011724021.1\|1187106_1187313_+	type II toxin-antitoxin system VapB family antitoxin	NA	NA	NA	NA
WP_003875391.1\|1187299_1187671_+	type II toxin-antitoxin system VapC family toxin	NA	NA	NA	NA
WP_003875392.1\|1187770_1188211_+	nitroreductase family deazaflavin-dependent oxidoreductase	NA	NA	NA	NA
WP_011724023.1\|1188276_1189014_-	glucose 1-dehydrogenase	Q06VL0	Trichoplusia_ni_ascovirus	1.6e-21	32.7
WP_011724024.1\|1189109_1189715_+	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_011724025.1\|1189816_1190215_+	glyoxalase/bleomycin resistance/dioxygenase family protein	NA	NA	NA	NA
WP_011724026.1\|1190283_1190667_+	hypothetical protein	NA	NA	NA	NA
WP_011724027.1\|1190736_1191069_+	hypothetical protein	NA	NA	NA	NA
WP_085989542.1\|1191246_1191774_+	glycoside hydrolase	A0A0K2FNG4	Mycobacterium_phage	1.5e-08	34.5
WP_009975396.1\|1192184_1192508_+	antibiotic biosynthesis monooxygenase	NA	NA	NA	NA
WP_009975397.1\|1192512_1193196_-	hypothetical protein	NA	NA	NA	NA
WP_009975398.1\|1193313_1193511_+	hypothetical protein	NA	NA	NA	NA
WP_009975399.1\|1193468_1194296_-	adenylate/guanylate cyclase domain-containing protein	NA	NA	NA	NA
WP_009975401.1\|1194418_1195828_+	glucose-6-phosphate dehydrogenase	H6WFS4	Cyanophage	3.5e-65	36.1
WP_009975403.1\|1195844_1196867_+	decarboxylating 6-phosphogluconate dehydrogenase	M1T2E7	Synechococcus_phage	3.2e-92	53.8
WP_003875404.1\|1196880_1197744_-	alpha/beta hydrolase	A0A0M4K6M8	Mollivirus	2.0e-07	29.8

DBSCAN-SWA_90

1201203 : 1202886

Stenotrophomonas_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_023861240.1\|1201203_1202886_-	pyruvate, phosphate dikinase	A0A2D2W2B1	Stenotrophomonas_phage	1.9e-70	37.6

DBSCAN-SWA_91

1216069 : 1216912

Lake_Baikal_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_011724041.1\|1216069_1216912_+	CbbQ/NirQ/NorQ/GpvN family protein	A0A2H4N7N3	Lake_Baikal_phage	6.5e-11	27.1

DBSCAN-SWA_92

1236773 : 1237487

Bacillus_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_019731812.1\|1236773_1237487_-	NAD-dependent deacylase	A0A068EPD4	Bacillus_phage	1.3e-20	33.1

DBSCAN-SWA_93

1249444 : 1251061

Escherichia_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_011724063.1\|1249444_1251061_+	nitrate reductase subunit beta	A0A077SL61	Escherichia_phage	1.1e-19	46.5

DBSCAN-SWA_94

1258779 : 1261380

Mamastrovirus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_085989568.1\|1258779_1261380_+	bifunctional FO biosynthesis protein CofGH	A9ZMK9	Mamastrovirus	2.6e-18	36.6

DBSCAN-SWA_95

1277230 : 1279179

Tupanvirus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_003875476.1\|1277230_1277923_+	adenylyl-sulfate kinase	A0A2K9L4R9	Tupanvirus	4.1e-27	39.3
WP_011724073.1\|1277919_1279179_+	sulfate adenylyltransferase	A0A2K9L4R9	Tupanvirus	2.3e-28	28.6

DBSCAN-SWA_96

1286704 : 1287667

Staphylococcus_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_009975530.1\|1286704_1287667_+	proline dehydrogenase	A0A2H4PQT6	Staphylococcus_phage	4.2e-30	30.5

DBSCAN-SWA_97

1299431 : 1300853

Hepacivirus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_009975544.1\|1299431_1300853_+	acyl-CoA synthetase	Q75ZG1	Hepacivirus	3.3e-31	32.3

DBSCAN-SWA_98

1304442 : 1305594

Mycobacterium_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_011724080.1\|1304442_1305594_+	PPE family protein	V5UPR1	Mycobacterium_phage	1.5e-05	32.6

DBSCAN-SWA_99

1321362 : 1322307

Staphylococcus_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_011724088.1\|1321362_1322307_-	ABC transporter ATP-binding protein	A0A2H4PQG7	Staphylococcus_phage	3.3e-19	27.5

DBSCAN-SWA_100

1325385 : 1326900

uncultured_Mediterranean_phage(100.0%)

protease

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_011724091.1\|1325385_1326900_+\|protease	trypsin-like serine protease	A0A1B1IRH0	uncultured_Mediterranean_phage	9.3e-08	31.1

DBSCAN-SWA_101

1336326 : 1337505

Planktothrix_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_011724098.1\|1336326_1337505_+	sn-glycerol-3-phosphate ABC transporter ATP-binding protein UgpC	G9BWD6	Planktothrix_phage	5.0e-25	36.7

DBSCAN-SWA_102

1359902 : 1360646

Diadromus_pulchellus_ascovirus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_033722436.1\|1359902_1360646_+	SDR family oxidoreductase	F2NZ40	Diadromus_pulchellus_ascovirus	2.1e-13	32.1

DBSCAN-SWA_103

1365257 : 1368094

Diachasmimorpha_longicaudata_entomopoxvirus(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_011724115.1\|1365257_1366958_+	DEAD/DEAH box helicase	Q5GF26	Diachasmimorpha_longicaudata_entomopoxvirus	2.8e-53	35.5
WP_011724116.1\|1366954_1368094_+	acyltransferase	C6ZR20	Salmonella_phage	4.9e-09	25.5

DBSCAN-SWA_104

1376014 : 1379914

Bacillus_virus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_033724924.1\|1376014_1379914_-	bifunctional diguanylate cyclase/phosphodiesterase	G3MA91	Bacillus_virus	1.7e-05	29.0

DBSCAN-SWA_105

1384524 : 1391841

Bacillus_phage(66.67%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_003875576.1\|1384524_1386339_-	protein kinase	M1I231	Acanthocystis_turfacea_Chlorella_virus	5.4e-18	30.7
WP_011724128.1\|1386436_1387582_-	FHA domain-containing protein	NA	NA	NA	NA
WP_011724129.1\|1387691_1388024_-	DUF732 domain-containing protein	NA	NA	NA	NA
WP_011724130.1\|1388170_1390087_-	ABC transporter ATP-binding protein	W8CYL7	Bacillus_phage	2.9e-46	28.1
WP_011724131.1\|1390083_1391841_-	ABC transporter ATP-binding protein	W8CYL7	Bacillus_phage	1.7e-40	27.0

DBSCAN-SWA_106

1402144 : 1403980

Planktothrix_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_011724139.1\|1402144_1403980_-	ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	2.5e-15	31.7

DBSCAN-SWA_107

1408198 : 1410049

Noumeavirus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_009975676.1\|1408198_1410049_+	adenylyl-sulfate kinase	A0A1Q1PNX7	Noumeavirus	2.0e-28	26.0

DBSCAN-SWA_108

1416665 : 1463054

Mycobacterium_phage(47.06%)

transposase,integrase

attL 1424428:1424487|attR 1458165:1459579

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_062908098.1\|1416665_1417355_-	hypothetical protein	A0A2D1GPL9	Mycobacterium_phage	4.5e-26	46.4
WP_011724145.1\|1417476_1417983_+	nitroreductase family deazaflavin-dependent oxidoreductase	NA	NA	NA	NA
WP_024637839.1\|1418103_1418535_-	hypothetical protein	NA	NA	NA	NA
WP_011724147.1\|1418531_1419593_-	hypothetical protein	G8I4U5	Mycobacterium_phage	8.5e-16	39.2
WP_011724148.1\|1419592_1419886_-	hypothetical protein	NA	NA	NA	NA
WP_085989543.1\|1421721_1422983_-\|transposase	IS3 family transposase	Q8W6R2	Burkholderia_virus	2.5e-70	54.0
WP_155255796.1\|1423249_1424158_-	hypothetical protein	NA	NA	NA	NA
1424428:1424487	attL	NA	NA	NA	NA
WP_011725525.1\|1424546_1425779_+\|transposase	IS256-like element IS1245 family transposase	A0A220NQR7	Corynebacterium_phage	2.5e-112	51.5
WP_080516337.1\|1425782_1426256_-	TniQ family protein	NA	NA	NA	NA
WP_052116727.1\|1426315_1426618_+	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_011724156.1\|1427272_1428580_-	ATP-binding protein	X5I2M2	Pseudomonas_phage	5.6e-09	27.1
WP_134796637.1\|1428717_1428981_-	hypothetical protein	NA	NA	NA	NA
WP_085989544.1\|1429128_1429332_-	antitoxin VbhA family protein	NA	NA	NA	NA
WP_011724159.1\|1429552_1430440_+	pyridoxal phosphate-dependent aminotransferase	NA	NA	NA	NA
WP_011724019.1\|1430393_1431698_-\|transposase	IS256-like element IS666 family transposase	A0A2P1JQX9	Mycobacterium_phage	2.1e-210	83.4
WP_155267857.1\|1431747_1432194_+	hypothetical protein	NA	NA	NA	NA
WP_099459082.1\|1432290_1432785_-	hypothetical protein	NA	NA	NA	NA
WP_080516338.1\|1432923_1434294_-	hypothetical protein	NA	NA	NA	NA
WP_033722440.1\|1434890_1436123_-\|transposase	IS256-like element IS1245 family transposase	A0A220NQR7	Corynebacterium_phage	2.1e-111	51.3
WP_085989545.1\|1438577_1439839_-\|transposase	IS3 family transposase	Q8W6R2	Burkholderia_virus	7.2e-70	52.2
WP_155267858.1\|1440783_1440936_-	hypothetical protein	NA	NA	NA	NA
WP_011724170.1\|1440991_1441171_+	hypothetical protein	NA	NA	NA	NA
WP_011724171.1\|1441978_1442449_-	hypothetical protein	NA	NA	NA	NA
WP_011724172.1\|1442412_1443501_-	hypothetical protein	G8I4U5	Mycobacterium_phage	5.1e-16	39.8
WP_011724148.1\|1443500_1443794_-	hypothetical protein	NA	NA	NA	NA
WP_031349784.1\|1445529_1446777_+\|transposase	IS256-like element IS1601 family transposase	A0A220NQR7	Corynebacterium_phage	9.8e-80	41.9
WP_011724175.1\|1447188_1448295_+\|integrase	site-specific integrase	A0A222ZND1	Mycobacterium_phage	1.9e-66	39.5
WP_011724176.1\|1448471_1448696_+	DNA-binding protein	NA	NA	NA	NA
WP_080516341.1\|1448777_1450232_+	hypothetical protein	A0A0F6WEU1	Mycobacterium_phage	5.1e-88	49.1
WP_141099007.1\|1450240_1451377_+	hypothetical protein	NA	NA	NA	NA
WP_132160312.1\|1451761_1452253_+	hypothetical protein	NA	NA	NA	NA
WP_011724181.1\|1452249_1452720_+	hypothetical protein	NA	NA	NA	NA
WP_024637502.1\|1452902_1453601_+	recombinase family protein	A0A286S1P7	Klebsiella_phage	8.4e-12	36.3
WP_011724184.1\|1453597_1453954_-	winged helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_024637503.1\|1454051_1454531_+	glyoxalase/bleomycin resistance/dioxygenase family protein	NA	NA	NA	NA
WP_011724186.1\|1454535_1455642_+	ACR3 family arsenite efflux transporter	NA	NA	NA	NA
WP_011724187.1\|1455638_1456313_+	arsenate reductase ArsC	A0A2H4PQT9	Staphylococcus_phage	6.0e-15	39.8
WP_023862343.1\|1456309_1456723_+	low molecular weight phosphatase family protein	NA	NA	NA	NA
WP_011725525.1\|1456872_1458105_-\|transposase	IS256-like element IS1245 family transposase	A0A220NQR7	Corynebacterium_phage	2.5e-112	51.5
WP_011724189.1\|1458358_1458619_+	hypothetical protein	NA	NA	NA	NA
WP_011724190.1\|1458615_1459335_+	hypothetical protein	NA	NA	NA	NA
WP_011724191.1\|1459344_1460160_+	hypothetical protein	W8ECM5	Mycobacterium_phage	6.7e-61	50.9
1458165:1459579	attR	NA	NA	NA	NA
WP_011724192.1\|1460156_1460462_+	hypothetical protein	NA	NA	NA	NA
WP_023882656.1\|1460661_1461189_+	hypothetical protein	NA	NA	NA	NA
WP_011724194.1\|1461521_1463054_+	hypothetical protein	G8I4L0	Mycobacterium_phage	2.9e-134	53.6

DBSCAN-SWA_109

1474658 : 1475318

Pandoravirus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_009975706.1\|1474658_1475318_+	threonylcarbamoyl-AMP synthase	S4VW33	Pandoravirus	1.3e-17	35.5

DBSCAN-SWA_110

1493401 : 1493899

Acanthamoeba_polyphaga_mimivirus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_010949605.1\|1493401_1493899_-	methylated-DNA--[protein]-cysteine S-methyltransferase	A0A0G2Y1B6	Acanthamoeba_polyphaga_mimivirus	1.3e-19	48.6

DBSCAN-SWA_111

1498156 : 1499791

uncultured_Mediterranean_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_009975725.1\|1498156_1499791_-	adenylate/guanylate cyclase domain-containing protein	A0A1B1IWY2	uncultured_Mediterranean_phage	2.5e-14	29.3

DBSCAN-SWA_112

1510911 : 1514292

Bacillus_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_033712534.1\|1510911_1512924_-	ATP-dependent DNA helicase	A0A127AW80	Bacillus_phage	8.5e-49	26.7
WP_009975739.1\|1512957_1514292_-	nicotinate phosphoribosyltransferase	G3MA18	Bacillus_virus	3.9e-42	34.9

DBSCAN-SWA_113

1520031 : 1520646

Ugandan_cassava_brown_streak_virus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_011724221.1\|1520031_1520646_+	RdgB/HAM1 family non-canonical purine NTP pyrophosphatase	A0A0P0A2M4	Ugandan_cassava_brown_streak_virus	1.3e-08	32.0

DBSCAN-SWA_114

1523778 : 1528121

Bacillus_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_024637120.1\|1523778_1526388_+	ATP-binding cassette domain-containing protein	W8CYL7	Bacillus_phage	1.7e-33	28.9
WP_011724227.1\|1526384_1528121_+	ABC transporter ATP-binding protein	W8CYL7	Bacillus_phage	2.1e-24	28.8

DBSCAN-SWA_115

1531939 : 1532689

Trichoplusia_ni_ascovirus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_015632616.1\|1531939_1532689_+	3-oxoacyl-ACP reductase FabG	Q06VL0	Trichoplusia_ni_ascovirus	5.5e-09	25.3

DBSCAN-SWA_116

1537434 : 1538991

Hepacivirus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_011724233.1\|1537434_1538991_-	acyl--CoA ligase	Q75ZG1	Hepacivirus	2.8e-15	23.5

DBSCAN-SWA_117

1561313 : 1562966

Tupanvirus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_011724243.1\|1561313_1562966_-	acyl-CoA synthetase	A0A2K9L3I8	Tupanvirus	2.8e-05	20.5

DBSCAN-SWA_118

1576697 : 1577855

Synechococcus_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_009975821.1\|1576697_1577855_-	Zn-dependent alcohol dehydrogenase	E3SJ82	Synechococcus_phage	1.2e-34	30.8

DBSCAN-SWA_119

1590274 : 1591771

Staphylococcus_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_011724256.1\|1590274_1591771_-	acyl--CoA ligase	A0A2H4PQM9	Staphylococcus_phage	5.8e-26	30.7

DBSCAN-SWA_120

1603787 : 1605353

Staphylococcus_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_009975862.1\|1603787_1605353_+	AMP-binding protein	A0A2H4PQM9	Staphylococcus_phage	3.9e-17	24.0

DBSCAN-SWA_121

1611981 : 1612704

Rhodococcus_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_009975877.1\|1611981_1612704_+	DUF1906 domain-containing protein	A0A2P1JXS5	Rhodococcus_phage	8.6e-52	49.3

DBSCAN-SWA_122

1634422 : 1636761

Vibrio_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_009975893.1\|1634422_1635070_-	oligoribonuclease	M4M9I5	Vibrio_phage	1.6e-25	40.9
WP_011724281.1\|1635195_1636761_+	DUF853 family protein	A0A248XCZ8	Klebsiella_phage	8.3e-60	36.6

DBSCAN-SWA_123

1640751 : 1642353

Pike_perch_iridovirus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_011724285.1\|1640751_1642353_+	acetyl-CoA carboxylase subunit beta	A0A1B2ITV7	Pike_perch_iridovirus	1.2e-18	62.5

DBSCAN-SWA_124

1651993 : 1656968

Burkholderia_virus(50.0%)

transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_085989545.1\|1651993_1653255_-\|transposase	IS3 family transposase	Q8W6R2	Burkholderia_virus	7.2e-70	52.2
WP_011724292.1\|1653446_1654106_-	cutinase family protein	NA	NA	NA	NA
WP_128971814.1\|1654292_1654583_+	hypothetical protein	NA	NA	NA	NA
WP_003873077.1\|1654828_1655137_+	hypothetical protein	NA	NA	NA	NA
WP_011724293.1\|1655720_1656968_+	alpha/beta hydrolase	A0A068F2G2	Mycobacterium_phage	7.4e-35	38.7

DBSCAN-SWA_125

1661599 : 1662860

Burkholderia_virus(100.0%)

transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_085989547.1\|1661599_1662860_+\|transposase	IS3 family transposase	Q8W6R2	Burkholderia_virus	7.2e-70	53.5

DBSCAN-SWA_126

1666413 : 1668651

Propionibacterium_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_009975923.1\|1666413_1666896_+	single-stranded DNA-binding protein	A0A1D8ETH0	Propionibacterium_phage	1.9e-15	36.7
WP_003875831.1\|1666974_1668651_+	energy-dependent translational throttle protein EttA	A0A2K9L0W2	Tupanvirus	6.2e-45	28.0

DBSCAN-SWA_127

1677951 : 1684028

Cyanophage(33.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_003875839.1\|1677951_1678599_+	HNH endonuclease	H6WG01	Cyanophage	1.5e-18	34.9
WP_003877446.1\|1678664_1678895_+	hypothetical protein	NA	NA	NA	NA
WP_085978482.1\|1678812_1679349_+	DUF5130 domain-containing protein	NA	NA	NA	NA
WP_011724301.1\|1679345_1681937_-	aminopeptidase N	A0A2K9L1R3	Tupanvirus	5.6e-45	31.6
WP_009975933.1\|1682044_1682668_+	DSBA oxidoreductase	NA	NA	NA	NA
WP_085978483.1\|1682714_1683203_+	ribose-5-phosphate isomerase	NA	NA	NA	NA
WP_009975935.1\|1683221_1684028_+	Fpg/Nei family DNA glycosylase	A0A1V0CNR6	Kaumoebavirus	4.8e-11	27.2

DBSCAN-SWA_128

1687592 : 1691326

Agrobacterium_phage(33.33%)

protease

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_009975941.1\|1687592_1688183_+\|protease	ATP-dependent Clp protease proteolytic subunit	A0A223W000	Agrobacterium_phage	3.6e-40	47.5
WP_003875849.1\|1688179_1688815_+\|protease	ATP-dependent Clp protease proteolytic subunit	A0A2H4JEX1	uncultured_Caudovirales_phage	6.7e-08	32.0
WP_011724302.1\|1688836_1689712_-	homocysteine S-methyltransferase	NA	NA	NA	NA
WP_003875851.1\|1690045_1691326_+\|protease	ATP-dependent Clp protease ATP-binding subunit ClpX	G3M9Z9	Bacillus_virus	1.9e-142	60.2

DBSCAN-SWA_129

1696327 : 1703176

Streptomyces_phage(33.33%)

tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_033724854.1\|1696327_1696861_+	transglycosylase family protein	A0A1J0GVU2	Streptomyces_phage	7.0e-27	77.6
WP_009975963.1\|1696930_1698190_+	enoyl reductase	NA	NA	NA	NA
WP_011724306.1\|1698248_1700897_+\|tRNA	valine--tRNA ligase	A0A1V0SK04	Klosneuvirus	3.4e-146	40.4
WP_003875858.1\|1700893_1702351_+	bifunctional folylpolyglutamate synthase/dihydrofolate synthase	NA	NA	NA	NA
WP_003875859.1\|1702347_1702725_+	DUF4233 domain-containing protein	NA	NA	NA	NA
WP_011724307.1\|1702765_1703176_+	nucleoside-diphosphate kinase	D2E8E1	Anguillid_herpesvirus	1.3e-28	51.5

DBSCAN-SWA_130

1708736 : 1709840

Streptococcus_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_011724310.1\|1708736_1709840_+	glutamate 5-kinase	A0A1X9I5D0	Streptococcus_phage	2.2e-54	38.3

DBSCAN-SWA_131

1725806 : 1727036

Streptococcus_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_033716413.1\|1725806_1727036_+	glutamate-5-semialdehyde dehydrogenase	A0A1X9I5D4	Streptococcus_phage	2.8e-95	51.0

DBSCAN-SWA_132

1738144 : 1741060

Catovirus(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_080516342.1\|1738144_1739881_-	AMP-binding protein	A0A1V0SBX8	Catovirus	8.5e-05	18.5
WP_011724324.1\|1739929_1741060_-	PE-PPE domain-containing protein	A0A222ZKN7	Mycobacterium_phage	2.6e-23	35.0

DBSCAN-SWA_133

1746554 : 1757594

Paenibacillus_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_011724326.1\|1746554_1757594_+	type I polyketide synthase	D0R7J2	Paenibacillus_phage	4.9e-29	29.6

DBSCAN-SWA_134

1770630 : 1772538

Tupanvirus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_044088770.1\|1770630_1772538_+	elongation factor 4	A0A2K9L6L3	Tupanvirus	4.6e-20	39.0

DBSCAN-SWA_135

1778799 : 1779888

Bacillus_virus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_009976059.1\|1778799_1779888_+	sulfate ABC transporter ATP-binding protein	G3M9Y6	Bacillus_virus	6.5e-27	37.3

DBSCAN-SWA_136

1785531 : 1786764

Corynebacterium_phage(100.0%)

transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_011725525.1\|1785531_1786764_-\|transposase	IS256-like element IS1245 family transposase	A0A220NQR7	Corynebacterium_phage	2.5e-112	51.5

DBSCAN-SWA_137

1800290 : 1801523

Corynebacterium_phage(100.0%)

transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_011725525.1\|1800290_1801523_-\|transposase	IS256-like element IS1245 family transposase	A0A220NQR7	Corynebacterium_phage	2.5e-112	51.5

DBSCAN-SWA_138

1827577 : 1828339

Mollivirus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_033722468.1\|1827577_1828339_+	SDR family oxidoreductase	A0A0M4JSW6	Mollivirus	4.0e-07	22.9

DBSCAN-SWA_139

1839258 : 1840758

Hepacivirus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_033722512.1\|1839258_1840758_+	long-chain fatty acid--CoA ligase	Q75ZG1	Hepacivirus	1.4e-35	28.7

DBSCAN-SWA_140

1851271 : 1852504

Corynebacterium_phage(100.0%)

transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_011725525.1\|1851271_1852504_-\|transposase	IS256-like element IS1245 family transposase	A0A220NQR7	Corynebacterium_phage	2.5e-112	51.5

DBSCAN-SWA_141

1861825 : 1867608

Staphylococcus_phage(50.0%)

transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_011724402.1\|1861825_1863388_+	AMP-binding protein	A0A2H4PQM9	Staphylococcus_phage	1.2e-29	25.6
WP_033722472.1\|1863384_1863870_-	CAP domain-containing protein	NA	NA	NA	NA
WP_033722521.1\|1863921_1864281_+	DUF732 domain-containing protein	NA	NA	NA	NA
WP_011724405.1\|1865538_1865853_-	hypothetical protein	NA	NA	NA	NA
WP_085989545.1\|1866346_1867608_-\|transposase	IS3 family transposase	Q8W6R2	Burkholderia_virus	7.2e-70	52.2

DBSCAN-SWA_142

1880649 : 1881910

Burkholderia_virus(100.0%)

transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_085989547.1\|1880649_1881910_+\|transposase	IS3 family transposase	Q8W6R2	Burkholderia_virus	7.2e-70	53.5

DBSCAN-SWA_143

1892545 : 1894081

Staphylococcus_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_033722481.1\|1892545_1894081_-	AMP-binding protein	A0A2H4PQM9	Staphylococcus_phage	2.2e-28	28.2

DBSCAN-SWA_144

1905146 : 1906601

Catovirus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_049770288.1\|1905146_1906601_+	acyl--CoA ligase	A0A1V0SBX8	Catovirus	1.9e-13	24.3

DBSCAN-SWA_145

1917941 : 1919246

Mycobacterium_phage(100.0%)

transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_011724019.1\|1917941_1919246_-\|transposase	IS256-like element IS666 family transposase	A0A2P1JQX9	Mycobacterium_phage	2.1e-210	83.4

DBSCAN-SWA_146

1932858 : 1933992

Tupanvirus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_011724472.1\|1932858_1933992_-	Zn-dependent alcohol dehydrogenase	A0A2K9L339	Tupanvirus	1.3e-14	28.8

DBSCAN-SWA_147

1947072 : 1951722

Staphylococcus_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_011724486.1\|1947072_1948683_+	AMP-binding protein	A0A2H4PQM9	Staphylococcus_phage	8.1e-26	28.3
WP_011724487.1\|1948669_1949494_+	SDR family NAD(P)-dependent oxidoreductase	NA	NA	NA	NA
WP_011724488.1\|1949500_1950106_-	MarR family transcriptional regulator	NA	NA	NA	NA
WP_011724489.1\|1950102_1951722_-	pyruvate, phosphate dikinase	A0A2D2W2B1	Stenotrophomonas_phage	5.5e-83	39.8

DBSCAN-SWA_148

1962063 : 1965651

Mycobacterium_phage(50.0%)

transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_011724501.1\|1962063_1963470_-\|transposase	IS1380-like element ISMav7 family transposase	A0A222ZN33	Mycobacterium_phage	2.6e-84	44.2
WP_155267860.1\|1963648_1964419_-	hypothetical protein	NA	NA	NA	NA
WP_011725525.1\|1964418_1965651_-\|transposase	IS256-like element IS1245 family transposase	A0A220NQR7	Corynebacterium_phage	2.5e-112	51.5

DBSCAN-SWA_149

1970943 : 1978027

Macacine_betaherpesvirus(33.33%)

transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_011724511.1\|1970943_1971576_-	membrane protein	A0A2I6B2H4	Macacine_betaherpesvirus	1.5e-28	44.4
WP_011724512.1\|1971728_1973249_-	PucR family transcriptional regulator	NA	NA	NA	NA
WP_155255794.1\|1973434_1973584_+	hypothetical protein	NA	NA	NA	NA
WP_011725525.1\|1973674_1974907_+\|transposase	IS256-like element IS1245 family transposase	A0A220NQR7	Corynebacterium_phage	2.5e-112	51.5
WP_003875975.1\|1975905_1976097_+	hypothetical protein	NA	NA	NA	NA
WP_003875976.1\|1976293_1976668_+	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_011724517.1\|1976947_1978027_+	GGDEF domain-containing protein	A0A2D0W9B6	Bordetella_phage	4.6e-09	45.9

DBSCAN-SWA_150

1990629 : 1997045

Pandoravirus(33.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_011724529.1\|1990629_1991691_+	3-deoxy-7-phosphoheptulonate synthase	S4W5F1	Pandoravirus	1.5e-81	48.3
WP_011724530.1\|1991785_1993441_-	AMP-binding protein	A0A1V0SBX8	Catovirus	7.8e-08	37.6
WP_023870986.1\|1993547_1997045_+	non-ribosomal peptide synthetase	A0A2K9KZV5	Tupanvirus	1.9e-43	23.9

DBSCAN-SWA_151

2002182 : 2013194

Tupanvirus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_011724535.1\|2002182_2008755_+	non-ribosomal peptide synthetase	A0A2K9KZV5	Tupanvirus	7.4e-126	24.5
WP_011724536.1\|2008751_2013194_+	non-ribosomal peptide synthetase	A0A2K9KZV5	Tupanvirus	4.5e-50	23.8

DBSCAN-SWA_152

2019373 : 2022523

Ectocarpus_siliculosus_virus(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_011724543.1\|2019373_2020519_+	molecular chaperone DnaJ	Q8QNB4	Ectocarpus_siliculosus_virus	4.3e-29	28.4
WP_003876005.1\|2020542_2021304_+	16S rRNA (uracil(1498)-N(3))-methyltransferase	NA	NA	NA	NA
WP_011724544.1\|2021464_2022523_+	PhoH family protein	A0A0S0MVD6	Pseudomonas_phage	3.0e-45	43.6

DBSCAN-SWA_153

2030596 : 2034412

Flavobacterium_phage(50.0%)

tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_011724550.1\|2030596_2031487_+	decaprenyl diphosphate synthase	R9W0U9	Flavobacterium_phage	1.2e-15	40.5
WP_011724551.1\|2031486_2031915_+	hypothetical protein	NA	NA	NA	NA
WP_011724552.1\|2031993_2032401_-	transcriptional repressor	NA	NA	NA	NA
WP_011724553.1\|2032397_2032829_-	winged helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_019732215.1\|2033020_2034412_+\|tRNA	glycine--tRNA ligase	A0A2I2L3K8	Orpheovirus	2.5e-47	29.5

DBSCAN-SWA_154

2040797 : 2042750

Abalone_shriveling_syndrome-associated_virus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_011724556.1\|2040797_2042750_+	DNA primase	B8Q5B5	Abalone_shriveling_syndrome-associated_virus	1.8e-35	31.9

DBSCAN-SWA_155

2048488 : 2054108

Streptococcus_phage(33.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_003872497.1\|2048488_2049421_-	cysteine synthase A	A0A1X9I5K7	Streptococcus_phage	6.4e-84	53.7
WP_011724563.1\|2049421_2050714_-	TQXA domain-containing protein	NA	NA	NA	NA
WP_003872495.1\|2051185_2052109_+	hypothetical protein	A0A2K9L690	Tupanvirus	2.8e-39	34.9
WP_011724564.1\|2052095_2054108_+	cysteine desulfurase	Q2XUY6	environmental_halophage	5.8e-98	42.6

DBSCAN-SWA_156

2069090 : 2070326

Corynebacterium_phage(100.0%)

transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_010948736.1\|2069090_2070326_-\|transposase	IS256-like element IS1311 family transposase	A0A220NQR7	Corynebacterium_phage	2.1e-111	53.2

DBSCAN-SWA_157

2077316 : 2079269

Tupanvirus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_011724581.1\|2077316_2079269_-	acyl-CoA oxidase	A0A2K9L6M4	Tupanvirus	1.2e-55	30.5

DBSCAN-SWA_158

2082384 : 2087894

Erysipelothrix_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_011724583.1\|2082384_2084346_+	ATP-binding cassette domain-containing protein	A0A2I4R674	Erysipelothrix_phage	2.5e-05	27.7
WP_011724584.1\|2084342_2085197_+	energy-coupling factor transporter transmembrane protein EcfT	NA	NA	NA	NA
WP_011724585.1\|2085221_2085668_-	Lrp/AsnC family transcriptional regulator	NA	NA	NA	NA
WP_023861414.1\|2085789_2086659_+	NG,NG-dimethylarginine dimethylaminohydrolase 1	NA	NA	NA	NA
WP_011724587.1\|2086655_2087894_+	ornithine--oxo-acid transaminase	A0A1V0SKB7	Klosneuvirus	2.9e-15	21.8

DBSCAN-SWA_159

2098609 : 2100883

Diadromus_pulchellus_ascovirus(50.0%)

transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_011724597.1\|2098609_2099455_+	oxidoreductase	F2NZ12	Diadromus_pulchellus_ascovirus	1.4e-08	30.6
WP_031349784.1\|2099635_2100883_+\|transposase	IS256-like element IS1601 family transposase	A0A220NQR7	Corynebacterium_phage	9.8e-80	41.9

DBSCAN-SWA_160

2126712 : 2128647

Catovirus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_009976349.1\|2126712_2128647_+	molecular chaperone HtpG	A0A1V0SAD6	Catovirus	8.9e-112	35.8

DBSCAN-SWA_161

2150770 : 2151955

Escherichia_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_033722560.1\|2150770_2151955_-	AAA family ATPase	A0A077SLJ9	Escherichia_phage	1.7e-57	35.4

DBSCAN-SWA_162

2156032 : 2157265

Corynebacterium_phage(100.0%)

transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_011725525.1\|2156032_2157265_+\|transposase	IS256-like element IS1245 family transposase	A0A220NQR7	Corynebacterium_phage	2.5e-112	51.5

DBSCAN-SWA_163

2164734 : 2236084

Corynebacterium_phage(30.0%)

transposase,integrase

attL 2155914:2155973|attR 2239812:2241228

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
2155914:2155973	attL	NA	NA	NA	NA
WP_011724631.1\|2164734_2166195_+	serine/threonine protein kinase	M1HUJ3	Paramecium_bursaria_Chlorella_virus	2.1e-12	27.5
WP_085989547.1\|2167604_2168865_+\|transposase	IS3 family transposase	Q8W6R2	Burkholderia_virus	7.2e-70	53.5
WP_011724635.1\|2169886_2170408_+	carboxymuconolactone decarboxylase family protein	NA	NA	NA	NA
WP_011724636.1\|2170404_2170950_+	carboxymuconolactone decarboxylase family protein	NA	NA	NA	NA
WP_011724637.1\|2171070_2171601_+	TetR/AcrR family transcriptional regulator	NA	NA	NA	NA
WP_033722564.1\|2171589_2172759_-	acyl-CoA dehydrogenase	NA	NA	NA	NA
WP_011724639.1\|2172817_2173594_+	N-acetylmuramoyl-L-alanine amidase	NA	NA	NA	NA
WP_003872393.1\|2173606_2174365_-	cutinase family protein	NA	NA	NA	NA
WP_003878208.1\|2174600_2174843_+	hypothetical protein	NA	NA	NA	NA
WP_011724640.1\|2175107_2176595_+	NAD(P)/FAD-dependent oxidoreductase	NA	NA	NA	NA
WP_011724641.1\|2176591_2177059_-	hypothetical protein	NA	NA	NA	NA
WP_011724642.1\|2177094_2177637_-	polyketide cyclase	NA	NA	NA	NA
WP_011724643.1\|2177784_2179092_-	cytochrome P450	NA	NA	NA	NA
WP_011724644.1\|2179123_2179471_-	hypothetical protein	NA	NA	NA	NA
WP_009976430.1\|2179559_2180645_+	dihydrodipicolinate reductase	NA	NA	NA	NA
WP_011724646.1\|2180754_2182422_+	Hsp70 family protein	NA	NA	NA	NA
WP_003872384.1\|2182434_2182782_-	hypothetical protein	NA	NA	NA	NA
WP_009976433.1\|2182873_2183941_-	hypothetical protein	NA	NA	NA	NA
WP_003872382.1\|2184033_2184657_-	MBL fold metallo-hydrolase	NA	NA	NA	NA
WP_009976436.1\|2185819_2186881_+	class I SAM-dependent methyltransferase	NA	NA	NA	NA
WP_009976437.1\|2186880_2187699_+	serine hydrolase	NA	NA	NA	NA
WP_003872378.1\|2187850_2188363_+	DUF3145 domain-containing protein	NA	NA	NA	NA
WP_009976439.1\|2188359_2189292_-	diacylglycerol kinase	NA	NA	NA	NA
WP_009976440.1\|2189288_2190869_-	FAD-binding oxidoreductase	NA	NA	NA	NA
WP_011724649.1\|2190916_2191498_+	TetR/AcrR family transcriptional regulator	NA	NA	NA	NA
WP_009976443.1\|2191494_2193036_+	glycerol-3-phosphate dehydrogenase/oxidase	NA	NA	NA	NA
WP_011724650.1\|2193129_2194650_+	NAD(P)-binding protein	NA	NA	NA	NA
WP_009976445.1\|2194728_2196150_-	acyl-CoA carboxylase subunit beta	NA	NA	NA	NA
WP_011724651.1\|2196191_2197514_-	beta-ketoacyl-ACP synthase	NA	NA	NA	NA
WP_011724652.1\|2197532_2198783_-	beta-ketoacyl-ACP synthase	NA	NA	NA	NA
WP_003872368.1\|2198779_2199127_-	acyl carrier protein	NA	NA	NA	NA
WP_003878192.1\|2199203_2200112_-	ACP S-malonyltransferase	NA	NA	NA	NA
WP_003878191.1\|2200252_2201578_-	PucR family transcriptional regulator	NA	NA	NA	NA
WP_009976448.1\|2201861_2204651_-	pyruvate dehydrogenase (acetyl-transferring), homodimeric type	NA	NA	NA	NA
WP_023884289.1\|2204823_2205411_+	hypothetical protein	NA	NA	NA	NA
WP_010949437.1\|2205486_2205930_+	DUF3052 domain-containing protein	NA	NA	NA	NA
WP_009976451.1\|2205929_2206391_+	peroxiredoxin	NA	NA	NA	NA
WP_080516392.1\|2206469_2207270_-	adenosylcobinamide amidohydrolase	NA	NA	NA	NA
WP_011724654.1\|2207359_2208478_+	epoxide hydrolase	NA	NA	NA	NA
WP_011724655.1\|2208484_2209300_-	DUF2236 domain-containing protein	NA	NA	NA	NA
WP_011724656.1\|2209352_2210297_+	cobalamin biosynthesis protein	NA	NA	NA	NA
WP_011724657.1\|2210278_2211109_-	SURF1 family protein	NA	NA	NA	NA
WP_009976459.1\|2211108_2211600_-	low molecular weight phosphotyrosine protein phosphatase	NA	NA	NA	NA
WP_033713208.1\|2211592_2212213_-	HAD-IA family hydrolase	NA	NA	NA	NA
WP_080516349.1\|2212309_2213380_+	threonine-phosphate decarboxylase	NA	NA	NA	NA
WP_009976462.1\|2213376_2214513_+	Nif3-like dinuclear metal center hexameric protein	NA	NA	NA	NA
WP_009976463.1\|2214509_2215247_+	hypothetical protein	NA	NA	NA	NA
WP_011724658.1\|2215243_2216395_+	bifunctional RNase H/acid phosphatase	A0A2L0V0T1	Agrobacterium_phage	6.6e-06	30.8
WP_011724659.1\|2216638_2217808_-	cytochrome P450	NA	NA	NA	NA
WP_011724660.1\|2217855_2218425_-	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_009976469.1\|2218471_2219122_+	class I SAM-dependent methyltransferase	NA	NA	NA	NA
WP_024637506.1\|2219106_2219817_-	2OG-Fe(II) oxygenase	NA	NA	NA	NA
WP_011724661.1\|2220319_2221468_-\|integrase	site-specific integrase	A0A1P8D5R0	Corynebacterium_phage	6.6e-30	29.9
WP_011724662.1\|2221769_2221979_+	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_011724663.1\|2222133_2222484_+	hypothetical protein	NA	NA	NA	NA
WP_031349784.1\|2222703_2223951_-\|transposase	IS256-like element IS1601 family transposase	A0A220NQR7	Corynebacterium_phage	9.8e-80	41.9
WP_011724019.1\|2226223_2227528_-\|transposase	IS256-like element IS666 family transposase	A0A2P1JQX9	Mycobacterium_phage	2.1e-210	83.4
WP_011724665.1\|2228525_2230199_-	type III restriction endonuclease	A0A2H4UUH6	Bodo_saltans_virus	1.5e-35	30.1
WP_033722573.1\|2230195_2230843_-	N-6 DNA methylase	NA	NA	NA	NA
WP_031349784.1\|2231077_2232325_+\|transposase	IS256-like element IS1601 family transposase	A0A220NQR7	Corynebacterium_phage	9.8e-80	41.9
WP_011724019.1\|2233373_2234678_+\|transposase	IS256-like element IS666 family transposase	A0A2P1JQX9	Mycobacterium_phage	2.1e-210	83.4
WP_011724668.1\|2234809_2236084_+\|transposase	IS256 family transposase	A0A218MNI5	uncultured_virus	2.9e-34	37.0
2239812:2241228	attR	NA	NA	NA	NA

DBSCAN-SWA_164

2239930 : 2241163

Corynebacterium_phage(100.0%)

transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_011725525.1\|2239930_2241163_+\|transposase	IS256-like element IS1245 family transposase	A0A220NQR7	Corynebacterium_phage	2.5e-112	51.5

DBSCAN-SWA_165

2262447 : 2271610

Corynebacterium_phage(50.0%)

transposase,integrase

attL 2257497:2257518|attR 2271621:2271642

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
2257497:2257518	attL	NA	NA	NA	NA
WP_011724687.1\|2262447_2262837_+	hypothetical protein	A0A2D1GA76	Mycobacterium_phage	1.7e-14	53.8
WP_031349784.1\|2263878_2265126_-\|transposase	IS256-like element IS1601 family transposase	A0A220NQR7	Corynebacterium_phage	9.8e-80	41.9
WP_011724689.1\|2265245_2265518_-	hypothetical protein	NA	NA	NA	NA
WP_155267863.1\|2265616_2266129_+	hypothetical protein	NA	NA	NA	NA
WP_155267864.1\|2266653_2267034_+	hypothetical protein	NA	NA	NA	NA
WP_085989547.1\|2267085_2268346_+\|transposase	IS3 family transposase	Q8W6R2	Burkholderia_virus	7.2e-70	53.5
WP_011724691.1\|2269208_2269544_-	hypothetical protein	NA	NA	NA	NA
WP_011724692.1\|2269540_2269735_-	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_011724693.1\|2269833_2270418_+	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_011724694.1\|2270401_2271610_+\|integrase	site-specific integrase	A0A1W6JRD7	Corynebacterium_phage	1.2e-26	28.7
2271621:2271642	attR	NA	NA	NA	NA

DBSCAN-SWA_166

2279184 : 2283694

Trichoplusia_ni_ascovirus(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_011724699.1\|2279184_2280963_+	SDR family oxidoreductase	Q06VL0	Trichoplusia_ni_ascovirus	6.0e-06	28.7
WP_003878156.1\|2281006_2281348_-	hypothetical protein	NA	NA	NA	NA
WP_011724700.1\|2281496_2281946_+	SRPBCC family protein	NA	NA	NA	NA
WP_024637207.1\|2282146_2283694_-	leucyl aminopeptidase	Q6GYZ8	Mycoplasma_phage	5.9e-34	33.3

DBSCAN-SWA_167

2289439 : 2294781

Streptococcus_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_003878146.1\|2289439_2290516_+	glycerate kinase	W6LM47	Streptococcus_phage	8.6e-16	30.4
WP_003872274.1\|2290613_2290970_+	iron-sulfur cluster assembly accessory protein	NA	NA	NA	NA
WP_003872273.1\|2290996_2291674_-	hypothetical protein	NA	NA	NA	NA
WP_009976513.1\|2291853_2292828_+	carbohydrate kinase family protein	NA	NA	NA	NA
WP_011724708.1\|2292849_2294781_-	asparagine synthase (glutamine-hydrolyzing)	I3UKG6	Ostreococcus_lucimarinus_virus	1.4e-19	27.6

DBSCAN-SWA_168

2303178 : 2311951

Acinetobacter_phage(33.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_023863740.1\|2303178_2304405_+	anthranilate phosphoribosyltransferase	A0A0N7IRD9	Acinetobacter_phage	1.2e-42	37.0
WP_011724712.1\|2304279_2306211_-	DEDD exonuclease domain-containing protein	NA	NA	NA	NA
WP_011724714.1\|2306423_2306618_+	hypothetical protein	NA	NA	NA	NA
WP_023861627.1\|2306798_2307956_+	C40 family peptidase	A0A1J0GW44	Streptomyces_phage	2.6e-18	43.2
WP_009976527.1\|2307987_2308818_+	hypothetical protein	NA	NA	NA	NA
WP_011724716.1\|2308855_2309989_+	glycosyltransferase family 4 protein	NA	NA	NA	NA
WP_009976530.1\|2310148_2311951_-	long-chain fatty acid--CoA ligase	A0A1V0SBX8	Catovirus	2.1e-51	25.7

DBSCAN-SWA_169

2317823 : 2318312

Mycobacterium_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_009976539.1\|2317823_2318312_+	polyadenylate-specific 3'-exoribonuclease AS	A0A249XQ39	Mycobacterium_phage	9.9e-28	44.3

DBSCAN-SWA_170

2321368 : 2322559

Acanthocystis_turfacea_Chlorella_virus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_009976542.1\|2321368_2322559_-	serine/threonine protein kinase	M1HJA5	Acanthocystis_turfacea_Chlorella_virus	4.3e-16	30.4

DBSCAN-SWA_171

2362598 : 2363846

Catovirus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_023861632.1\|2362598_2363846_+	cysteine--1-D-myo-inosityl 2-amino-2-deoxy-alpha-D-glucopyranoside ligase	A0A1V0SAQ2	Catovirus	3.7e-26	24.7

DBSCAN-SWA_172

2367694 : 2368927

Corynebacterium_phage(100.0%)

transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_033720551.1\|2367694_2368927_-\|transposase	IS256-like element IS1245 family transposase	A0A220NQR7	Corynebacterium_phage	7.4e-112	51.3

DBSCAN-SWA_173

2381719 : 2383207

Mycobacterium_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_011724750.1\|2381719_2383207_+	MFS transporter	A0A0M3UL24	Mycobacterium_phage	1.9e-37	32.7

DBSCAN-SWA_174

2398166 : 2401955

Dickeya_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_023863781.1\|2398166_2401955_+	methionine synthase	A0A140XBC7	Dickeya_phage	1.5e-14	58.1

DBSCAN-SWA_175

2420882 : 2422712

Tupanvirus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_003872166.1\|2420882_2422712_+	proteasome ATPase	A0A2K9L596	Tupanvirus	2.7e-33	35.4

DBSCAN-SWA_176

2435821 : 2436778

Rhodococcus_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_024637316.1\|2435821_2436778_-	5'-3' exonuclease	A0A2P1JXG8	Rhodococcus_phage	2.5e-22	33.7

DBSCAN-SWA_177

2456571 : 2457327

Planktothrix_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_003872133.1\|2456571_2457327_+	ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	3.5e-24	32.2

DBSCAN-SWA_178

2471984 : 2486580

Sulfolobus_monocaudavirus(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_023861529.1\|2471984_2472788_+	polyprenol monophosphomannose synthase	A0A0N7A8R9	Sulfolobus_monocaudavirus	4.5e-25	39.8
WP_003872122.1\|2472795_2473131_-	RNA polymerase-binding protein RbpA	NA	NA	NA	NA
WP_003878051.1\|2473301_2473652_+	hypothetical protein	NA	NA	NA	NA
WP_033722612.1\|2474067_2486580_+	type I polyketide synthase	D0R7J2	Paenibacillus_phage	2.5e-29	29.0

DBSCAN-SWA_179

2500128 : 2501646

Mollivirus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_011724808.1\|2500128_2501646_+	carboxylesterase/lipase family protein	A0A0M4JT58	Mollivirus	8.1e-28	31.0

DBSCAN-SWA_180

2506414 : 2506975

Indivirus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_011724811.1\|2506414_2506975_+	pyrazinamidase PncA	A0A1V0SEH9	Indivirus	2.2e-07	27.0

DBSCAN-SWA_181

2512406 : 2514454

Planktothrix_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_029248479.1\|2512406_2513492_+	sn-glycerol-3-phosphate ABC transporter ATP-binding protein UgpC	G9BWD6	Planktothrix_phage	9.6e-23	31.2
WP_003876738.1\|2513485_2514454_+	patatin-like phospholipase family protein	A0A0H3TN97	Faustovirus	3.7e-18	28.2

DBSCAN-SWA_182

2524109 : 2528426

Burkholderia_virus(50.0%)

transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_085989545.1\|2524109_2525371_-\|transposase	IS3 family transposase	Q8W6R2	Burkholderia_virus	7.2e-70	52.2
WP_080516355.1\|2525438_2526023_+	hypothetical protein	NA	NA	NA	NA
WP_019732500.1\|2526057_2527368_-	acyltransferase	NA	NA	NA	NA
WP_011724823.1\|2527454_2528426_+	aldo/keto reductase	A0A2H4PQR8	Staphylococcus_phage	7.6e-11	26.1

DBSCAN-SWA_183

2540370 : 2541153

Trichoplusia_ni_ascovirus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_011724835.1\|2540370_2541153_+	glucose 1-dehydrogenase	Q06VL0	Trichoplusia_ni_ascovirus	1.7e-13	29.7

DBSCAN-SWA_184

2552570 : 2553803

Corynebacterium_phage(100.0%)

transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_011725525.1\|2552570_2553803_-\|transposase	IS256-like element IS1245 family transposase	A0A220NQR7	Corynebacterium_phage	2.5e-112	51.5

DBSCAN-SWA_185

2558457 : 2563224

Mycobacterium_phage(50.0%)

transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_011724019.1\|2558457_2559762_+\|transposase	IS256-like element IS666 family transposase	A0A2P1JQX9	Mycobacterium_phage	2.1e-210	83.4
WP_080516358.1\|2559816_2560365_-	TetR/AcrR family transcriptional regulator	NA	NA	NA	NA
WP_011724852.1\|2560852_2562433_+\|transposase	IS21 family transposase	NA	NA	NA	NA
WP_009979999.1\|2562429_2563224_+	ATP-binding protein	U5N3V8	Enterobacteria_phage	1.6e-30	33.9

DBSCAN-SWA_186

2612887 : 2614387

Hepacivirus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_033722638.1\|2612887_2614387_+	long-chain fatty acid--CoA ligase	Q75ZG1	Hepacivirus	5.2e-35	30.8

DBSCAN-SWA_187

2623224 : 2624787

Staphylococcus_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_011724902.1\|2623224_2624787_+	AMP-binding protein	A0A2H4PQM9	Staphylococcus_phage	4.3e-32	26.4

DBSCAN-SWA_188

2634037 : 2635555

Catovirus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_011724907.1\|2634037_2635555_+	long-chain fatty acid--CoA ligase	A0A1V0SBX8	Catovirus	2.5e-08	25.9

DBSCAN-SWA_189

2648117 : 2649725

Staphylococcus_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_011724921.1\|2648117_2649725_-	AMP-binding protein	A0A2H4PQM9	Staphylococcus_phage	2.0e-24	26.8

DBSCAN-SWA_190

2659484 : 2660984

Catovirus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_011724929.1\|2659484_2660984_+	acyl--CoA ligase	A0A1V0SBX8	Catovirus	1.8e-11	30.3

DBSCAN-SWA_191

2665994 : 2731152

Enterobacteria_phage(22.22%)

protease,transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_011725525.1\|2665994_2667227_-\|transposase	IS256-like element IS1245 family transposase	A0A220NQR7	Corynebacterium_phage	2.5e-112	51.5
WP_033722644.1\|2668332_2669532_+	thiolase	NA	NA	NA	NA
WP_009953845.1\|2669528_2669984_+	acyl dehydratase	NA	NA	NA	NA
WP_009953846.1\|2669988_2670198_+	hypothetical protein	NA	NA	NA	NA
WP_011724937.1\|2670478_2671048_-	TetR/AcrR family transcriptional regulator	NA	NA	NA	NA
WP_011724938.1\|2671323_2672403_+	hypothetical protein	NA	NA	NA	NA
WP_049770293.1\|2672715_2673873_+	cytochrome P450	NA	NA	NA	NA
WP_011724940.1\|2673898_2674738_+	NAD(P)-dependent oxidoreductase	NA	NA	NA	NA
WP_014379538.1\|2674734_2675556_+	mycofactocin-coupled SDR family oxidoreductase	NA	NA	NA	NA
WP_011724942.1\|2675572_2677174_+	AMP-binding protein	A0A1V0SBX8	Catovirus	1.9e-11	36.7
WP_033722647.1\|2677170_2677761_-	nuclear transport factor 2 family protein	NA	NA	NA	NA
WP_009953855.1\|2677757_2678681_-	SDR family NAD(P)-dependent oxidoreductase	NA	NA	NA	NA
WP_009953857.1\|2678677_2679112_-	Zn-ribbon domain-containing OB-fold protein	NA	NA	NA	NA
WP_011724944.1\|2679105_2679909_-	enoyl-CoA hydratase	NA	NA	NA	NA
WP_011724945.1\|2679905_2681180_-	cytochrome P450	NA	NA	NA	NA
WP_009953861.1\|2681323_2682406_+	Gfo/Idh/MocA family oxidoreductase	NA	NA	NA	NA
WP_011724946.1\|2682590_2683094_+	hypothetical protein	NA	NA	NA	NA
WP_080516395.1\|2683124_2683916_-	SDR family oxidoreductase	NA	NA	NA	NA
WP_009953864.1\|2684121_2685255_-	NDMA-dependent alcohol dehydrogenase	A0A2K9L339	Tupanvirus	1.2e-15	28.8
WP_011724948.1\|2685271_2686735_-	aldehyde dehydrogenase	NA	NA	NA	NA
WP_009953866.1\|2686813_2687248_+	dehydratase MaoC	NA	NA	NA	NA
WP_009953867.1\|2687244_2687730_+	hypothetical protein	NA	NA	NA	NA
WP_011724949.1\|2687742_2689083_+	TetR/AcrR family transcriptional regulator	NA	NA	NA	NA
WP_009953869.1\|2689096_2690323_-	CoA transferase	NA	NA	NA	NA
WP_020188802.1\|2690505_2691579_+	CoA transferase	NA	NA	NA	NA
WP_009953872.1\|2691570_2692434_-	3-carboxyethylcatechol 2,3-dioxygenase	NA	NA	NA	NA
WP_155254932.1\|2692488_2692656_-	hypothetical protein	NA	NA	NA	NA
WP_014382043.1\|2692672_2693587_-	spirocyclase AveC family protein	NA	NA	NA	NA
WP_011724954.1\|2693819_2694860_+	spirocyclase AveC family protein	NA	NA	NA	NA
WP_011724955.1\|2694866_2695457_-	TetR family transcriptional regulator	NA	NA	NA	NA
WP_011724956.1\|2695624_2696815_+	cytochrome P450	NA	NA	NA	NA
WP_011724957.1\|2696838_2697759_-	TIGR03619 family F420-dependent LLM class oxidoreductase	NA	NA	NA	NA
WP_009953881.1\|2698000_2698366_+	hypothetical protein	NA	NA	NA	NA
WP_011724958.1\|2698365_2698974_+	nitroreductase	NA	NA	NA	NA
WP_011724959.1\|2698993_2701144_+	acyl-CoA dehydrogenase	NA	NA	NA	NA
WP_009953884.1\|2701157_2702294_+	lipid-transfer protein	NA	NA	NA	NA
WP_033722650.1\|2702290_2702701_+	hypothetical protein	NA	NA	NA	NA
WP_011724961.1\|2702717_2703539_+	mycofactocin-coupled SDR family oxidoreductase	NA	NA	NA	NA
WP_011724962.1\|2703558_2704677_-	phosphotransferase	NA	NA	NA	NA
WP_020188798.1\|2704780_2705227_-	hypothetical protein	NA	NA	NA	NA
WP_009953890.1\|2705223_2706366_-	acyl-CoA dehydrogenase	NA	NA	NA	NA
WP_011724019.1\|2706694_2707999_+\|transposase	IS256-like element IS666 family transposase	A0A2P1JQX9	Mycobacterium_phage	2.1e-210	83.4
WP_033722651.1\|2708783_2710229_+	long-chain fatty acid--CoA ligase	A0A2H4PQM9	Staphylococcus_phage	1.8e-29	26.6
WP_020415599.1\|2710529_2710922_+	DUF732 domain-containing protein	NA	NA	NA	NA
WP_011724852.1\|2711639_2713220_+\|transposase	IS21 family transposase	NA	NA	NA	NA
WP_009979999.1\|2713216_2714011_+	ATP-binding protein	U5N3V8	Enterobacteria_phage	1.6e-30	33.9
WP_085989545.1\|2714286_2715547_+\|transposase	IS3 family transposase	Q8W6R2	Burkholderia_virus	7.2e-70	52.2
WP_011724970.1\|2716403_2717459_+	hydrogenase expression protein HypE	NA	NA	NA	NA
WP_011724971.1\|2717506_2719303_+	nickel-dependent hydrogenase large subunit	NA	NA	NA	NA
WP_011724972.1\|2719306_2720257_+	NifU family protein	NA	NA	NA	NA
WP_033722652.1\|2720253_2720898_+	hypothetical protein	NA	NA	NA	NA
WP_011724974.1\|2720894_2721548_+	hypothetical protein	NA	NA	NA	NA
WP_011724975.1\|2721544_2722915_+	hypothetical protein	NA	NA	NA	NA
WP_080516396.1\|2723057_2723489_+\|protease	hydrogenase maturation protease	NA	NA	NA	NA
WP_024637381.1\|2724519_2725251_-	haloacid dehalogenase type II	NA	NA	NA	NA
WP_011724852.1\|2725777_2727358_+\|transposase	IS21 family transposase	NA	NA	NA	NA
WP_009979999.1\|2727354_2728149_+	ATP-binding protein	U5N3V8	Enterobacteria_phage	1.6e-30	33.9
WP_011724980.1\|2728204_2728426_+	hypothetical protein	NA	NA	NA	NA
WP_011724981.1\|2728693_2728879_+	hypothetical protein	NA	NA	NA	NA
WP_085989547.1\|2729890_2731152_-\|transposase	IS3 family transposase	Q8W6R2	Burkholderia_virus	7.2e-70	53.5

DBSCAN-SWA_192

2742474 : 2743185

Trichoplusia_ni_ascovirus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_011724989.1\|2742474_2743185_-	SDR family oxidoreductase	Q06VL0	Trichoplusia_ni_ascovirus	2.5e-11	29.7

DBSCAN-SWA_193

2755525 : 2756287

Trichoplusia_ni_ascovirus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_011725003.1\|2755525_2756287_-	SDR family oxidoreductase	Q06VL0	Trichoplusia_ni_ascovirus	2.3e-15	31.8

DBSCAN-SWA_194

2761319 : 2769775

Cyanophage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_011725008.1\|2761319_2762837_-	glucose-6-phosphate dehydrogenase	H6WFS4	Cyanophage	1.4e-72	36.0
WP_003876669.1\|2762977_2763160_+	hypothetical protein	NA	NA	NA	NA
WP_011725009.1\|2763185_2764163_-	hypothetical protein	NA	NA	NA	NA
WP_011725010.1\|2764239_2765751_-	hypothetical protein	NA	NA	NA	NA
WP_033722654.1\|2765830_2769775_-	ATP-dependent RNA helicase HrpA	A0A1V0SBU4	Catovirus	1.8e-34	25.8

DBSCAN-SWA_195

2778300 : 2779473

Shahe_endorna-like_virus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_009976848.1\|2778300_2779473_+	glycosyltransferase	A0A1L3KK54	Shahe_endorna-like_virus	3.0e-06	42.9

DBSCAN-SWA_196

2787206 : 2788022

Gordonia_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_009976855.1\|2787206_2788022_-	DUF1906 domain-containing protein	A0A2D1GEF2	Gordonia_phage	2.1e-54	48.6

DBSCAN-SWA_197

2804448 : 2805219

Megavirus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_023861610.1\|2804448_2805219_+	SDR family oxidoreductase	L7Y2R3	Megavirus	1.2e-08	34.6

DBSCAN-SWA_198

2824971 : 2827601

Burkholderia_virus(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_033711805.1\|2824971_2826219_+	MFS transporter	Q6JIH2	Burkholderia_virus	2.5e-14	26.3
WP_011725055.1\|2826296_2827601_-	competence/damage-inducible protein A	B5TK85	Pseudomonas_phage	1.8e-15	41.4

DBSCAN-SWA_199

2837876 : 2843456

Macacine_betaherpesvirus(66.67%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_023861636.1\|2837876_2838890_+	alcohol dehydrogenase catalytic domain-containing protein	A0A0G2YAX3	Acanthamoeba_polyphaga_mimivirus	9.9e-30	28.3
WP_011725064.1\|2838934_2839501_+	YceI family protein	NA	NA	NA	NA
WP_033722682.1\|2839517_2840669_-	hypothetical protein	NA	NA	NA	NA
WP_003876576.1\|2841246_2842239_+	esterase family protein	A0A2I6B0H1	Macacine_betaherpesvirus	4.2e-166	85.4
WP_011725067.1\|2842349_2842913_+	chorismate mutase	NA	NA	NA	NA
WP_033706294.1\|2843018_2843456_+	transglycosylase family protein	A0A2I6B0Z0	Macacine_betaherpesvirus	5.7e-51	67.6

DBSCAN-SWA_200

2848560 : 2851133

Corynebacterium_phage(100.0%)

transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_033722689.1\|2848560_2849811_-\|transposase	IS256-like element IS1601 family transposase	A0A220NQR7	Corynebacterium_phage	1.3e-79	41.3
WP_011725525.1\|2849900_2851133_+\|transposase	IS256-like element IS1245 family transposase	A0A220NQR7	Corynebacterium_phage	2.5e-112	51.5

DBSCAN-SWA_201

2864533 : 2864971

Bodo_saltans_virus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_011725086.1\|2864533_2864971_-	DUF1810 domain-containing protein	A0A2H4UVK5	Bodo_saltans_virus	1.7e-15	40.7

DBSCAN-SWA_202

2886603 : 2887719

Planktothrix_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_009976991.1\|2886603_2887719_-	sulfate/molybdate ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	3.6e-17	32.7

DBSCAN-SWA_203

2897220 : 2902114

Ostreococcus_lucimarinus_virus(33.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_031344201.1\|2897220_2898690_+	NADP-dependent phosphogluconate dehydrogenase	A0A0P0C6S9	Ostreococcus_lucimarinus_virus	8.7e-35	27.0
WP_011725105.1\|2898729_2900166_+	GuaB1 family IMP dehydrogenase-related protein	A0A1V0SHK8	Klosneuvirus	2.6e-44	29.2
WP_009977006.1\|2900250_2900556_+	acyl carrier protein	NA	NA	NA	NA
WP_011725106.1\|2900548_2902114_+	long-chain-fatty acid--ACP ligase MbtM	A0A2H4PQM9	Staphylococcus_phage	6.5e-12	26.6

DBSCAN-SWA_204

2913236 : 2916062

Prochlorococcus_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_011725113.1\|2913236_2916062_-	aminomethyl-transferring glycine dehydrogenase	M4QFZ1	Prochlorococcus_phage	1.7e-257	50.9

DBSCAN-SWA_205

2926843 : 2928763

Bacillus_virus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_003876498.1\|2926843_2928763_+	ABC transporter ATP-binding protein/permease	G3M9Y6	Bacillus_virus	2.6e-07	24.5

DBSCAN-SWA_206

2934015 : 2934735

Bacillus_virus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_011725124.1\|2934015_2934735_-	MgtC/SapB family protein	G3MA03	Bacillus_virus	1.9e-11	36.7

DBSCAN-SWA_207

2942537 : 2943770

Corynebacterium_phage(100.0%)

transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_011725525.1\|2942537_2943770_-\|transposase	IS256-like element IS1245 family transposase	A0A220NQR7	Corynebacterium_phage	2.5e-112	51.5

DBSCAN-SWA_208

2947612 : 2952499

Mycobacterium_phage(100.0%)

protease

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_024637409.1\|2947612_2949445_-	type VII secretion system ESX-5 AAA family ATPase EccA5	V5UQM2	Mycobacterium_phage	3.7e-67	32.6
WP_011725132.1\|2949441_2950650_-	type VII secretion protein EccE	NA	NA	NA	NA
WP_011725133.1\|2950669_2952499_-\|protease	type VII secretion system ESX-5 serine protease mycosin MycP5	A0A0A7HDD8	Mycobacterium_phage	1.4e-71	35.3

DBSCAN-SWA_209

2965033 : 2970717

Mycobacterium_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_003877884.1\|2965033_2969203_-	type VII secretion protein EccC	V5UPA0	Mycobacterium_phage	2.7e-113	26.3
WP_003876467.1\|2969199_2970717_-	type VII secretion protein EccB	V5UN45	Mycobacterium_phage	2.0e-71	36.8

DBSCAN-SWA_210

2986671 : 2988195

Catovirus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_009977091.1\|2986671_2988195_+	acyl-CoA synthetase	A0A1V0SBX8	Catovirus	1.4e-06	20.1

DBSCAN-SWA_211

2992592 : 2993960

Chrysochromulina_ericina_virus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_011725158.1\|2992592_2993960_+	DEAD/DEAH box helicase	A0A0N9Q9J4	Chrysochromulina_ericina_virus	7.8e-38	27.1

DBSCAN-SWA_212

3000422 : 3001232

Bacillus_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_011725162.1\|3000422_3001232_+	RNA polymerase sigma factor SigF	A0A0E3T5M9	Bacillus_phage	4.1e-18	30.6

DBSCAN-SWA_213

3009974 : 3013173

uncultured_virus(100.0%)

transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_011724668.1\|3009974_3011249_-\|transposase	IS256 family transposase	A0A218MNI5	uncultured_virus	2.9e-34	37.0
WP_011724668.1\|3011898_3013173_+\|transposase	IS256 family transposase	A0A218MNI5	uncultured_virus	2.9e-34	37.0

DBSCAN-SWA_214

3045739 : 3048328

Pithovirus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_011725196.1\|3045739_3048328_-	ATP-binding cassette domain-containing protein	W5SAS9	Pithovirus	6.5e-25	27.9

DBSCAN-SWA_215

3062319 : 3063243

Moumouvirus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_009977158.1\|3062319_3063243_+	alpha/beta hydrolase	M1PGN2	Moumouvirus	1.9e-32	29.0

DBSCAN-SWA_216

3073995 : 3077197

Corynebacterium_phage(50.0%)

transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_031349784.1\|3073995_3075243_-\|transposase	IS256-like element IS1601 family transposase	A0A220NQR7	Corynebacterium_phage	9.8e-80	41.9
WP_011725215.1\|3075451_3077197_+	3-ketosteroid-delta-1-dehydrogenase	A0A2P0ZL82	Lactobacillus_phage	5.5e-20	25.3

DBSCAN-SWA_217

3091669 : 3124900

Acanthamoeba_polyphaga_mimivirus(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_009977201.1\|3091669_3093475_-	N-acetylglutaminylglutamine amidotransferase	A0A0G2Y369	Acanthamoeba_polyphaga_mimivirus	6.7e-29	26.4
WP_011725225.1\|3093634_3124900_-	non-ribosomal peptide synthetase	A0A2K9KZV5	Tupanvirus	3.5e-149	26.4

DBSCAN-SWA_218

3131460 : 3138164

uncultured_Mediterranean_phage(25.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_009977237.1\|3131460_3132168_-	SMC-Scp complex subunit ScpB	A0A1B1IVT7	uncultured_Mediterranean_phage	4.4e-08	27.6
WP_003876325.1\|3132164_3132983_-	segregation/condensation protein A	NA	NA	NA	NA
WP_009977240.1\|3132979_3133843_-	ParA family protein	Q8JL10	Natrialba_phage	1.5e-23	36.9
WP_011725231.1\|3134080_3134833_+	SAM-dependent methyltransferase	NA	NA	NA	NA
WP_009977243.1\|3134858_3135800_-	site-specific tyrosine recombinase XerD	A0A0K2CP59	Brevibacillus_phage	1.0e-20	25.9
WP_003876321.1\|3135796_3136420_-	NUDIX hydrolase	NA	NA	NA	NA
WP_003876320.1\|3136412_3138164_-	CTP synthase	A0A1J0FA14	Only_Syngen_Nebraska_virus	2.3e-127	46.0

DBSCAN-SWA_219

3146658 : 3150809

Cronobacter_phage(33.33%)

tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_011725237.1\|3146658_3147924_-\|tRNA	tyrosine--tRNA ligase	K4F5T3	Cronobacter_phage	1.7e-63	37.9
WP_003876309.1\|3147935_3148574_-	DNA-3-methyladenine glycosylase	NA	NA	NA	NA
WP_011725238.1\|3148658_3149936_+	ammonium transporter	H8ZJB2	Ostreococcus_tauri_virus	2.1e-37	30.1
WP_011725239.1\|3150047_3150809_+	ABC transporter ATP-binding protein	A0A2H4PQG7	Staphylococcus_phage	5.7e-22	30.7

DBSCAN-SWA_220

3162215 : 3163322

Oenococcus_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_011725249.1\|3162215_3163322_+	mandelate racemase	Q6A202	Oenococcus_phage	2.3e-16	22.0

DBSCAN-SWA_221

3170312 : 3173377

Erysipelothrix_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_033722713.1\|3170312_3172088_+	ABC-F family ATP-binding cassette domain-containing protein	A0A2I4R674	Erysipelothrix_phage	1.6e-38	25.3
WP_011725258.1\|3172093_3173377_+	cytochrome P450	L7RCT3	Acanthamoeba_polyphaga_moumouvirus	6.5e-10	26.4

DBSCAN-SWA_222

3177688 : 3190469

Paenibacillus_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_033722714.1\|3177688_3184114_-	type I polyketide synthase	D0R7J2	Paenibacillus_phage	1.5e-22	30.1
WP_011725262.1\|3184094_3190469_-	type I polyketide synthase	D0R7J2	Paenibacillus_phage	5.8e-27	33.0

DBSCAN-SWA_223

3195792 : 3197022

Mycobacterium_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_011725267.1\|3195792_3197022_-	acetylornithine transaminase	B5LJF5	Mycobacterium_phage	1.7e-15	31.2

DBSCAN-SWA_224

3202788 : 3203832

Orpheovirus(100.0%)

tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_009977305.1\|3202788_3203832_-\|tRNA	phenylalanine--tRNA ligase subunit alpha	A0A2I2L4E3	Orpheovirus	1.1e-26	36.2

DBSCAN-SWA_225

3208581 : 3213009

Vibrio_phage(50.0%)

tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_075362228.1\|3208581_3209187_-	translation initiation factor IF-3	A0A2I7S9Q1	Vibrio_phage	1.6e-11	34.5
WP_085989553.1\|3209427_3213009_+\|tRNA	bifunctional lysylphosphatidylglycerol synthetase/lysine--tRNA ligase LysX	A0A1V0SIS0	Klosneuvirus	2.7e-74	35.4

DBSCAN-SWA_226

3220900 : 3227715

uncultured_Mediterranean_phage(33.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_011725278.1\|3220900_3223816_-	excinuclease ABC subunit UvrA	A0A1B1IVR3	uncultured_Mediterranean_phage	7.0e-294	53.1
WP_031344328.1\|3223923_3224610_+	MBL fold metallo-hydrolase	A0A221J762	Mycobacterium_phage	4.4e-13	74.4
WP_009977337.1\|3224627_3225071_-	universal stress protein	NA	NA	NA	NA
WP_033711996.1\|3225356_3226940_+	membrane protein	NA	NA	NA	NA
WP_003876250.1\|3226992_3227715_+	membrane protein	G3MA03	Bacillus_virus	1.9e-11	44.3

DBSCAN-SWA_227

3233521 : 3240768

Bodo_saltans_virus(25.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_011725287.1\|3233521_3235597_-	serine/threonine protein kinase	A0A2H4UVE2	Bodo_saltans_virus	9.8e-16	28.2
WP_076221025.1\|3235846_3238423_+	ATP-binding cassette domain-containing protein	A0A2R8FG22	Brazilian_cedratvirus	8.7e-30	36.6
WP_011725289.1\|3238520_3238985_+	DUF402 domain-containing protein	NA	NA	NA	NA
WP_011725290.1\|3238981_3239980_+	ATP-dependent DNA ligase	G8GER3	unidentified_phage	3.3e-09	29.8
WP_011725291.1\|3239979_3240768_+	Fpg/Nei family DNA glycosylase	G3MA33	Bacillus_virus	4.7e-11	23.4

DBSCAN-SWA_228

3246169 : 3253525

Listeria_phage(33.33%)

transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_033722716.1\|3246169_3248920_-	DNA polymerase I	A8ASX2	Listeria_phage	4.0e-41	27.9
WP_003876233.1\|3249018_3249459_+	Zn-ribbon domain-containing OB-fold protein	NA	NA	NA	NA
WP_003876232.1\|3249455_3250670_+	lipid-transfer protein	NA	NA	NA	NA
WP_009977356.1\|3250780_3251395_-	ANTAR domain-containing response regulator	Q6XM27	Feldmannia_irregularis_virus	5.1e-05	31.7
WP_080555747.1\|3251863_3252109_-	hypothetical protein	NA	NA	NA	NA
WP_031349784.1\|3252277_3253525_-\|transposase	IS256-like element IS1601 family transposase	A0A220NQR7	Corynebacterium_phage	9.8e-80	41.9

DBSCAN-SWA_229

3259988 : 3261623

Paramecium_bursaria_Chlorella_virus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_049770295.1\|3259988_3261623_+	thiol reductant ABC exporter subunit CydC	M1ID50	Paramecium_bursaria_Chlorella_virus	1.6e-05	26.9

DBSCAN-SWA_230

3269563 : 3272705

Acinetobacter_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_003877736.1\|3269563_3270382_-	indole-3-glycerol phosphate synthase TrpC	A0A0P0IR83	Acinetobacter_phage	3.2e-31	36.9
WP_011725307.1\|3270495_3271176_-	TIGR02234 family membrane protein	NA	NA	NA	NA
WP_011725308.1\|3271172_3272705_-	anthranilate synthase component I	S4VNU7	Pandoravirus	8.8e-38	39.9

DBSCAN-SWA_231

3285283 : 3286009

Streptomyces_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_019732226.1\|3285283_3286009_+	NUDIX hydrolase	A0A0E3JJF3	Streptomyces_phage	2.4e-09	34.5

DBSCAN-SWA_232

3299549 : 3304859

Klosneuvirus(33.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_011725324.1\|3299549_3300866_-	adenosylmethionine--8-amino-7-oxononanoate transaminase	A0A1V0SKB7	Klosneuvirus	8.4e-13	27.8
WP_011725325.1\|3300928_3301396_+	hypothetical protein	NA	NA	NA	NA
WP_011725326.1\|3301727_3302597_+	NlpC/P60 family peptidoglycan-binding protein RipD	A0A1J0GW44	Streptomyces_phage	2.7e-07	37.4
WP_011725327.1\|3302696_3304859_+	acyltransferase	A0A166XZF2	Gordonia_phage	1.7e-58	30.2

DBSCAN-SWA_233

3319014 : 3325429

Catovirus(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_011725335.1\|3319014_3320835_-	long-chain fatty acid--CoA ligase	A0A1V0SBX8	Catovirus	2.4e-42	26.3
WP_011725336.1\|3320856_3321273_-	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_011725337.1\|3321331_3321778_+	PPOX class F420-dependent oxidoreductase	NA	NA	NA	NA
WP_011725338.1\|3321895_3325429_-	DNA polymerase III subunit alpha	Q8W6C3	Saccharomonospora_phage	0.0e+00	59.7

DBSCAN-SWA_234

3334183 : 3337345

Orpheovirus(100.0%)

tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_011725347.1\|3334183_3337345_-\|tRNA	isoleucine--tRNA ligase	A0A2I2L3Y0	Orpheovirus	7.3e-164	36.4

DBSCAN-SWA_235

3359108 : 3360370

Burkholderia_virus(100.0%)

transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_155267868.1\|3359108_3360370_-\|transposase	IS3 family transposase	Q8W6R2	Burkholderia_virus	5.5e-70	53.5

DBSCAN-SWA_236

3365015 : 3384864

Tupanvirus(66.67%)

transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_011725353.1\|3365015_3372674_-	non-ribosomal peptide synthetase	A0A2K9KZV5	Tupanvirus	1.1e-99	20.6
WP_011725354.1\|3372670_3382918_-	non-ribosomal peptide synthetase	A0A2K9KZV5	Tupanvirus	6.9e-70	25.6
WP_011725355.1\|3382962_3383193_-	MbtH family protein	NA	NA	NA	NA
WP_031349784.1\|3383616_3384864_-\|transposase	IS256-like element IS1601 family transposase	A0A220NQR7	Corynebacterium_phage	9.8e-80	41.9

DBSCAN-SWA_237

3395417 : 3416953

Shahe_endorna-like_virus(30.0%)

transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_011724668.1\|3395417_3396692_+\|transposase	IS256 family transposase	A0A218MNI5	uncultured_virus	2.9e-34	37.0
WP_085989554.1\|3396651_3397800_+	glycosyltransferase	NA	NA	NA	NA
WP_011725363.1\|3397802_3398852_+	polysaccharide pyruvyl transferase family protein	NA	NA	NA	NA
WP_099459086.1\|3398848_3399526_+	class I SAM-dependent methyltransferase	NA	NA	NA	NA
WP_011725365.1\|3399658_3400915_+	glycosyltransferase	A0A1L3KK54	Shahe_endorna-like_virus	5.6e-06	38.7
WP_011725366.1\|3400921_3401701_-	SDR family NAD(P)-dependent oxidoreductase	NA	NA	NA	NA
WP_009977500.1\|3401774_3402530_-	methyltransferase	NA	NA	NA	NA
WP_023862302.1\|3402692_3403499_-	macrocin O-methyltransferase	A0A2R8FDY2	Brazilian_cedratvirus	1.6e-54	51.7
WP_080516362.1\|3403595_3404882_-	glycosyltransferase	A0A1L3KK54	Shahe_endorna-like_virus	6.1e-08	39.5
WP_085989547.1\|3405109_3406370_+\|transposase	IS3 family transposase	Q8W6R2	Burkholderia_virus	7.2e-70	53.5
WP_009977506.1\|3406636_3407914_-	glycosyltransferase	A0A1L3KK54	Shahe_endorna-like_virus	2.5e-06	39.1
WP_009977507.1\|3408036_3408843_-	macrocin O-methyltransferase	A0A2R8FDY2	Brazilian_cedratvirus	2.1e-54	50.7
WP_024636696.1\|3409124_3410228_-	class I SAM-dependent methyltransferase	NA	NA	NA	NA
WP_009977510.1\|3410515_3411565_-	NAD-dependent epimerase/dehydratase family protein	L7RCI0	Acanthamoeba_polyphaga_moumouvirus	6.5e-16	23.5
WP_011725373.1\|3411696_3412722_-	sulfotransferase family protein	NA	NA	NA	NA
WP_085989547.1\|3412779_3414041_-\|transposase	IS3 family transposase	Q8W6R2	Burkholderia_virus	7.2e-70	53.5
WP_031347731.1\|3414520_3415435_-	sulfotransferase family protein	NA	NA	NA	NA
WP_023861235.1\|3415756_3416953_-	acyltransferase	A9YX16	Burkholderia_phage	7.1e-19	28.7

DBSCAN-SWA_238

3426081 : 3427536

Bacillus_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_011725377.1\|3426081_3427536_-	HAMP domain-containing histidine kinase	W8CYF6	Bacillus_phage	5.2e-16	24.8

DBSCAN-SWA_239

3436033 : 3436801

Trichoplusia_ni_ascovirus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_011725384.1\|3436033_3436801_-	beta-ketoacyl-ACP reductase	Q06VL0	Trichoplusia_ni_ascovirus	4.0e-07	26.2

DBSCAN-SWA_240

3441090 : 3443263

Gordonia_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_003876096.1\|3441090_3441825_-	NlpC/P60 family peptidoglycan endopeptidase RipB	A0A0K0NL58	Gordonia_phage	9.1e-17	37.6
WP_023861230.1\|3441850_3443263_-	NlpC/P60 family peptidoglycan endopeptidase RipA	Q9T1E7	Lactobacillus_phage	1.3e-11	44.6

DBSCAN-SWA_241

3448004 : 3450851

Tupanvirus(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_003876090.1\|3448004_3449642_-	ABC-F family ATP-binding cassette domain-containing protein	A0A2K9L0W2	Tupanvirus	8.2e-34	23.7
WP_009977560.1\|3449665_3450475_-	enoyl-CoA hydratase	NA	NA	NA	NA
WP_003877663.1\|3450497_3450851_-	thioredoxin	A0A2H4P7M6	Pseudomonas_phage	8.5e-13	33.7

DBSCAN-SWA_242

3454889 : 3457405

Mycobacterium_phage(33.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_031344234.1\|3454889_3455354_-	SUF system NifU family Fe-S cluster assembly protein	A0A0K1LSF9	Mycobacterium_phage	1.8e-23	47.8
WP_019732423.1\|3455372_3456620_-	cysteine desulfurase	Q2XUY6	environmental_halophage	2.4e-102	46.3
WP_003876081.1\|3456622_3457405_-	Fe-S cluster assembly ATPase SufC	W8CYL7	Bacillus_phage	1.0e-05	26.7

DBSCAN-SWA_243

3462611 : 3463520

Staphylococcus_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_003877656.1\|3462611_3463520_+	ABC transporter ATP-binding protein	A0A2H4PQG7	Staphylococcus_phage	3.3e-16	28.8

DBSCAN-SWA_244

3471599 : 3476223

Synechococcus_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_011725400.1\|3471599_3473156_+	glucose-6-phosphate dehydrogenase	E3SJC5	Synechococcus_phage	5.0e-73	36.0
WP_024637748.1\|3473171_3474083_+	glucose-6-phosphate dehydrogenase assembly protein OpcA	NA	NA	NA	NA
WP_011725402.1\|3474079_3474835_+	6-phosphogluconolactonase	NA	NA	NA	NA
WP_003876065.1\|3474876_3475275_+	hypothetical protein	NA	NA	NA	NA
WP_011725404.1\|3475293_3476223_+	histone deacetylase family protein	A0A2K9KZC4	Tupanvirus	5.9e-45	35.5

DBSCAN-SWA_245

3491507 : 3492893

Staphylococcus_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_084249115.1\|3491507_3492893_+	bile acid CoA ligase	A0A2H4PQM9	Staphylococcus_phage	6.7e-29	28.4

DBSCAN-SWA_246

3502706 : 3504676

Streptococcus_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_085989577.1\|3502706_3503771_-	uridine diphosphate-N-acetylglucosamine-binding protein YvcK	A1IMD5	Streptococcus_phage	8.2e-35	35.8
WP_011725422.1\|3503779_3504676_-	RNase adapter RapZ	A0A0R8VB27	Thermobifida_phage	5.0e-09	31.6

DBSCAN-SWA_247

3508717 : 3514649

Staphylococcus_phage(75.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_009977644.1\|3508717_3509200_-	6,7-dimethyl-8-ribityllumazine synthase	A0A2H4PQS3	Staphylococcus_phage	1.1e-13	40.5
WP_011725426.1\|3509249_3510527_-	bifunctional 3,4-dihydroxy-2-butanone-4-phosphate synthase/GTP cyclohydrolase II	A0A2H4PQS2	Staphylococcus_phage	7.9e-93	46.1
WP_003872540.1\|3510648_3511248_-	riboflavin synthase	A0A2H4PQS5	Staphylococcus_phage	1.5e-30	39.7
WP_003877628.1\|3511366_3512074_+	LppX_LprAFG lipoprotein	NA	NA	NA	NA
WP_003872542.1\|3512070_3513627_+	MFS transporter	NA	NA	NA	NA
WP_011725427.1\|3513623_3514649_-	bifunctional diaminohydroxyphosphoribosylaminopyrimidine deaminase/5-amino-6-(5-phosphoribosylamino)uracil reductase RibD	A0A1V0SE20	Indivirus	5.3e-39	35.4

DBSCAN-SWA_248

3522237 : 3523200

Acanthamoeba_polyphaga_mimivirus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_011725433.1\|3522237_3523200_+	alpha/beta hydrolase	A0A2L2DMU8	Acanthamoeba_polyphaga_mimivirus	2.0e-24	33.0

DBSCAN-SWA_249

3527409 : 3531086

Staphylococcus_phage(33.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_008258192.1\|3527409_3528621_-	methionine adenosyltransferase	A0A2H4PQS6	Staphylococcus_phage	8.6e-113	54.7
WP_011725438.1\|3528715_3529990_-	bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase CoaBC	Q9HH70	Methanothermobacter_phage	3.0e-39	33.7
WP_009977666.1\|3530011_3530338_-	DNA-directed RNA polymerase subunit omega	NA	NA	NA	NA
WP_023861214.1\|3530414_3531086_-	guanylate kinase	K4JYM5	Abalone_herpesvirus	1.3e-14	32.6

DBSCAN-SWA_250

3536566 : 3540504

Halovirus(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_009977672.1\|3536566_3537688_-	glutamine-hydrolyzing carbamoyl-phosphate synthase small subunit	R4TGJ8	Halovirus	8.4e-38	31.8
WP_009977674.1\|3537684_3538197_-	hypothetical protein	NA	NA	NA	NA
WP_009977676.1\|3538258_3539551_-	dihydroorotase	NA	NA	NA	NA
WP_003872564.1\|3539547_3540504_-	aspartate carbamoyltransferase	A7RB08	Paramecium_bursaria_Chlorella_virus	2.3e-28	33.6

DBSCAN-SWA_251

3545690 : 3546419

Bacillus_virus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_033710755.1\|3545690_3546419_-	ABC transporter ATP-binding protein	G3M9Y6	Bacillus_virus	7.9e-29	34.3

DBSCAN-SWA_252

3561867 : 3564738

Pandoravirus(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_011725453.1\|3561867_3563073_-	chorismate synthase	A0A291AU41	Pandoravirus	2.1e-47	36.7
WP_011725454.1\|3563130_3564738_-	ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	2.3e-20	34.2

DBSCAN-SWA_253

3575900 : 3581624

Klosneuvirus(50.0%)

tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_003872646.1\|3575900_3578603_-\|tRNA	alanine--tRNA ligase	A0A1V0SK38	Klosneuvirus	3.3e-64	33.8
WP_011725463.1\|3578686_3579088_-	hypothetical protein	NA	NA	NA	NA
WP_009977718.1\|3579241_3579865_+	hypothetical protein	NA	NA	NA	NA
WP_009977719.1\|3579939_3580275_-	hypothetical protein	NA	NA	NA	NA
WP_033720743.1\|3580271_3581624_-	replication-associated recombination protein A	G3MBE0	Bacillus_virus	6.7e-82	43.5

DBSCAN-SWA_254

3595771 : 3596650

Rhodococcus_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_003872663.1\|3595771_3596650_+	zinc metallopeptidase	A0A1I9SA48	Rhodococcus_phage	7.0e-56	49.8

DBSCAN-SWA_255

3608099 : 3615701

Brazilian_cedratvirus(33.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_011725483.1\|3608099_3609752_+	protein kinase	A0A2R8FDX7	Brazilian_cedratvirus	1.6e-13	27.0
WP_031345041.1\|3609755_3612122_-	RelA/SpoT family protein	A0A2I2L310	Orpheovirus	7.5e-12	37.9
WP_011725485.1\|3612165_3612708_-	adenine phosphoribosyltransferase	NA	NA	NA	NA
WP_011725486.1\|3612715_3614389_-	hypothetical protein	NA	NA	NA	NA
WP_011725487.1\|3614393_3615701_-	protein translocase subunit SecF	A0A1B1IVP7	uncultured_Mediterranean_phage	1.3e-21	30.6

DBSCAN-SWA_256

3619655 : 3625455

Catovirus(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_011725490.1\|3619655_3623177_+	carboxylic acid reductase	A0A1V0SBX8	Catovirus	3.7e-15	22.0
WP_003872683.1\|3623242_3623920_-	hypothetical protein	NA	NA	NA	NA
WP_003872684.1\|3624399_3625455_-	Holliday junction branch migration DNA helicase RuvB	A0A127AWE7	Bacillus_phage	1.0e-05	22.9

DBSCAN-SWA_257

3628907 : 3630479

Heterosigma_akashiwo_virus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_011725495.1\|3628907_3630479_+	polyamine aminopropyltransferase	A0A1C9C533	Heterosigma_akashiwo_virus	1.4e-06	30.1

DBSCAN-SWA_258

3638128 : 3641943

Tupanvirus(50.0%)

tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_009977800.1\|3638128_3640183_-\|tRNA	threonine--tRNA ligase	A0A2K9L6B6	Tupanvirus	1.5e-104	34.9
WP_033722750.1\|3640218_3641943_+	Na+/H+ antiporter	A0A2H4J178	uncultured_Caudovirales_phage	1.8e-07	26.9

DBSCAN-SWA_259

3665035 : 3666583

Staphylococcus_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_011725519.1\|3665035_3666583_+	long-chain-fatty-acid--CoA ligase	A0A2H4PQM9	Staphylococcus_phage	8.6e-33	26.9

DBSCAN-SWA_260

3670517 : 3722795

Corynebacterium_phage(50.0%)

protease,transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_009979999.1\|3670517_3671312_-	ATP-binding protein	U5N3V8	Enterobacteria_phage	1.6e-30	33.9
WP_011724852.1\|3671308_3672889_-\|transposase	IS21 family transposase	NA	NA	NA	NA
WP_031349784.1\|3673145_3674393_+\|transposase	IS256-like element IS1601 family transposase	A0A220NQR7	Corynebacterium_phage	9.8e-80	41.9
WP_011725525.1\|3674453_3675686_+\|transposase	IS256-like element IS1245 family transposase	A0A220NQR7	Corynebacterium_phage	2.5e-112	51.5
WP_003878587.1\|3675778_3676078_+	hypothetical protein	NA	NA	NA	NA
WP_080516365.1\|3676269_3676584_+	hypothetical protein	NA	NA	NA	NA
WP_011725527.1\|3676660_3677182_+	hypothetical protein	NA	NA	NA	NA
WP_033706185.1\|3677189_3678458_-	amidohydrolase	NA	NA	NA	NA
WP_011725528.1\|3678481_3679696_-	amidohydrolase	NA	NA	NA	NA
WP_009977852.1\|3679699_3680503_-	acetoacetate decarboxylase family protein	NA	NA	NA	NA
WP_011725529.1\|3680499_3681438_-	SDR family oxidoreductase	NA	NA	NA	NA
WP_024637188.1\|3681505_3682390_+	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_011725531.1\|3682386_3683661_-	amidohydrolase	NA	NA	NA	NA
WP_011725532.1\|3683750_3683969_+	hypothetical protein	NA	NA	NA	NA
WP_009977858.1\|3684042_3684420_+	DUF4189 domain-containing protein	NA	NA	NA	NA
WP_009977863.1\|3684515_3684887_+	DUF732 domain-containing protein	NA	NA	NA	NA
WP_023861165.1\|3684817_3685495_-	TetR/AcrR family transcriptional regulator	NA	NA	NA	NA
WP_011725533.1\|3685571_3686402_+	mycofactocin-coupled SDR family oxidoreductase	NA	NA	NA	NA
WP_009977866.1\|3686403_3687225_+	mycofactocin-coupled SDR family oxidoreductase	NA	NA	NA	NA
WP_011725534.1\|3687208_3688024_+	hypothetical protein	NA	NA	NA	NA
WP_011725535.1\|3688027_3689491_+	aldehyde dehydrogenase	NA	NA	NA	NA
WP_003875280.1\|3689587_3689800_+	hypothetical protein	NA	NA	NA	NA
WP_011725536.1\|3689966_3690887_+	cation transporter	NA	NA	NA	NA
WP_011725537.1\|3690917_3691847_-	cytochrome c oxidase assembly protein	NA	NA	NA	NA
WP_003875277.1\|3691875_3692220_-	DUF732 domain-containing protein	NA	NA	NA	NA
WP_011725538.1\|3692417_3692786_-	DUF732 domain-containing protein	NA	NA	NA	NA
WP_011725539.1\|3692885_3693638_+\|protease	ATP-dependent Clp protease ATP-binding subunit	A0A249XSS8	Mycobacterium_phage	4.6e-16	37.8
WP_023861158.1\|3693677_3694205_+	hypothetical protein	NA	NA	NA	NA
WP_011725541.1\|3694192_3694723_+	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_085989556.1\|3694700_3695822_-	cell division protein ZapE	NA	NA	NA	NA
WP_011725543.1\|3695820_3696585_+	pyrimidine reductase family protein	NA	NA	NA	NA
WP_003875270.1\|3696599_3698159_+	alpha/beta hydrolase	NA	NA	NA	NA
WP_003875269.1\|3698187_3699474_+	DUF2029 domain-containing protein	NA	NA	NA	NA
WP_009977893.1\|3699818_3700223_+	peptide-methionine (R)-S-oxide reductase MsrB	NA	NA	NA	NA
WP_011725525.1\|3700931_3702164_-\|transposase	IS256-like element IS1245 family transposase	A0A220NQR7	Corynebacterium_phage	2.5e-112	51.5
WP_011725547.1\|3702694_3703447_-	class I SAM-dependent methyltransferase	A0A1B1IS97	uncultured_Mediterranean_phage	2.5e-06	27.8
WP_003875265.1\|3703443_3704139_-	chlorite dismutase family protein	NA	NA	NA	NA
WP_011725548.1\|3705497_3706571_-	uroporphyrinogen decarboxylase	NA	NA	NA	NA
WP_011725549.1\|3706618_3707440_+	enoyl-CoA hydratase/isomerase family protein	NA	NA	NA	NA
WP_016706020.1\|3707567_3708185_+	DUF3000 domain-containing protein	NA	NA	NA	NA
WP_011725550.1\|3708186_3709473_+	ribonuclease D	NA	NA	NA	NA
WP_011725551.1\|3709512_3711438_-	1-deoxy-D-xylulose-5-phosphate synthase	NA	NA	NA	NA
WP_009977925.1\|3711511_3711955_+	CBS domain-containing protein	NA	NA	NA	NA
WP_009977927.1\|3711971_3713261_+	ArsB/NhaD family transporter	NA	NA	NA	NA
WP_011725552.1\|3713340_3714528_-	class I SAM-dependent RNA methyltransferase	NA	NA	NA	NA
WP_011725553.1\|3714548_3716543_-	APC family permease	NA	NA	NA	NA
WP_003878611.1\|3716670_3717336_+	TrkA family potassium uptake protein	NA	NA	NA	NA
WP_003875253.1\|3717491_3718148_+	TrkA family potassium uptake protein	NA	NA	NA	NA
WP_003878612.1\|3718159_3718801_-	DUF3159 domain-containing protein	NA	NA	NA	NA
WP_011725555.1\|3718860_3719211_-	OB-fold nucleic acid binding domain-containing protein	NA	NA	NA	NA
WP_031349784.1\|3719419_3720667_+\|transposase	IS256-like element IS1601 family transposase	A0A220NQR7	Corynebacterium_phage	9.8e-80	41.9
WP_011725556.1\|3720759_3721458_+	hypothetical protein	NA	NA	NA	NA
WP_011725557.1\|3721473_3722250_-	DUF3710 domain-containing protein	NA	NA	NA	NA
WP_003875248.1\|3722330_3722795_-	dUTP diphosphatase	A0A2L1IVN2	Streptomyces_phage	6.8e-26	51.8

DBSCAN-SWA_261

3726428 : 3727958

Cyanophage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_023861150.1\|3726428_3727958_+	RNA polymerase sigma factor	M4SMP8	Cyanophage	4.5e-42	34.3

DBSCAN-SWA_262

3731252 : 3743089

Mycobacterium_phage(40.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_085978474.1\|3731252_3731501_-	DUF3039 domain-containing protein	A0A059VGG3	Mycobacterium_phage	7.8e-13	43.8
WP_010949740.1\|3731572_3732034_+	DUF3099 domain-containing protein	NA	NA	NA	NA
WP_024637055.1\|3732154_3733144_+	sigma-70 family RNA polymerase sigma factor	M4SMP8	Cyanophage	6.7e-39	36.9
WP_003875234.1\|3733273_3733963_+	metal-dependent transcriptional regulator	NA	NA	NA	NA
WP_003875233.1\|3734007_3735069_-	DUF4192 domain-containing protein	NA	NA	NA	NA
WP_003878620.1\|3735182_3736598_+	Si-specific NAD(P)(+) transhydrogenase	A0A2K5B2C5	Erysipelothrix_phage	1.1e-42	27.6
WP_011725564.1\|3736602_3737439_-	trypsin-like peptidase domain-containing protein	NA	NA	NA	NA
WP_011725565.1\|3737668_3738643_+	PAC2 family protein	NA	NA	NA	NA
WP_003875228.1\|3738698_3739730_+	alpha/beta hydrolase	A0A0B5A484	Mycobacterium_phage	1.7e-16	28.9
WP_011725566.1\|3739768_3740422_+	PhzF family phenazine biosynthesis protein	NA	NA	NA	NA
WP_011725567.1\|3740443_3740929_-	FABP family protein	NA	NA	NA	NA
WP_003875225.1\|3740967_3741432_-	transcriptional repressor NrdR	NA	NA	NA	NA
WP_011725568.1\|3741583_3742078_-	LysM peptidoglycan-binding domain-containing protein	NA	NA	NA	NA
WP_009977973.1\|3742390_3743089_+	repressor LexA	A0A1B1P7Q3	Bacillus_phage	6.0e-10	49.2

DBSCAN-SWA_263

3752063 : 3753311

Corynebacterium_phage(100.0%)

transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_031349784.1\|3752063_3753311_-\|transposase	IS256-like element IS1601 family transposase	A0A220NQR7	Corynebacterium_phage	9.8e-80	41.9

DBSCAN-SWA_264

3757621 : 3758674

Mycobacterium_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_003875210.1\|3757621_3758674_-	recombinase RecA	A0A2D1GPX2	Mycobacterium_phage	2.7e-131	73.7

DBSCAN-SWA_265

3765603 : 3767928

Mycobacterium_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_031347706.1\|3765603_3767928_-	DNA translocase FtsK	S5VNE3	Mycobacterium_phage	4.3e-113	59.7

DBSCAN-SWA_266

3773067 : 3773820

Gordonia_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_003878641.1\|3773067_3773820_-	FAD-dependent thymidylate synthase	A0A166Y9A6	Gordonia_phage	1.4e-49	54.4

DBSCAN-SWA_267

3777332 : 3781519

Ralstonia_phage(33.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_009978008.1\|3777332_3777878_-	dihydrofolate reductase	A0A1L7N103	Ralstonia_phage	1.2e-21	42.9
WP_009978009.1\|3777874_3778675_-	thymidylate synthase	A0A1B3AY68	Gordonia_phage	1.9e-108	69.7
WP_003875187.1\|3778717_3779458_+	hypothetical protein	NA	NA	NA	NA
WP_033722776.1\|3779446_3780682_-	glycosyltransferase family 1 protein	NA	NA	NA	NA
WP_011725594.1\|3780739_3781519_-	SDR family oxidoreductase	A0A0M4JSW6	Mollivirus	9.1e-07	25.1

DBSCAN-SWA_268

3792560 : 3793556

Aureococcus_anophage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_011725603.1\|3792560_3793556_-	Rieske 2Fe-2S domain-containing protein	A0A076FFT9	Aureococcus_anophage	1.3e-05	25.3

DBSCAN-SWA_269

3801103 : 3802426

Acanthamoeba_polyphaga_lentillevirus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_085989579.1\|3801103_3802426_-	insulinase family protein	J3IZ03	Acanthamoeba_polyphaga_lentillevirus	1.1e-28	23.8

DBSCAN-SWA_270

3818821 : 3821566

Bodo_saltans_virus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_011725621.1\|3818821_3821566_-	translation initiation factor IF-2	A0A2H4UTS4	Bodo_saltans_virus	2.4e-17	22.5

DBSCAN-SWA_271

3828086 : 3829703

Mycobacterium_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_003875137.1\|3828086_3829703_-	MFS transporter	A0A0M3UL24	Mycobacterium_phage	8.1e-42	32.4

DBSCAN-SWA_272

3838076 : 3839456

Erysipelothrix_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_011725633.1\|3838076_3839456_+	mycothione reductase	A0A2K5B2C5	Erysipelothrix_phage	4.2e-31	26.7

DBSCAN-SWA_273

3843541 : 3846391

Mollivirus(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_031353881.1\|3843541_3844315_-	3-oxoacyl-ACP reductase	A0A0M4JSW6	Mollivirus	5.6e-09	29.4
WP_024637963.1\|3845677_3846391_-	gamma-glutamyl-gamma-aminobutyrate hydrolase family protein	A0A2P9FI75	Pseudomonas_phage	3.4e-08	29.9

DBSCAN-SWA_274

3872982 : 3873888

Brevibacillus_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_011725651.1\|3872982_3873888_-	tyrosine recombinase XerC	A0A0K2CP59	Brevibacillus_phage	2.4e-19	27.0

DBSCAN-SWA_275

3880467 : 3883610

Eastern_grey_kangaroopox_virus(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_003878714.1\|3880467_3881457_-	SDR family oxidoreductase	A0A2C9DTC1	Eastern_grey_kangaroopox_virus	2.8e-05	29.7
WP_011725657.1\|3881745_3882516_+	GAF and ANTAR domain-containing protein	NA	NA	NA	NA
WP_003875077.1\|3882522_3882828_-	DUF2469 domain-containing protein	NA	NA	NA	NA
WP_003875076.1\|3882890_3883610_-	ribonuclease HII	G4YAY0	Emiliania_huxleyi_virus	1.1e-19	36.8

DBSCAN-SWA_276

3896110 : 3897850

Saccharomonospora_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_011725666.1\|3896110_3897850_+	DEAD/DEAH box helicase	I4AZM6	Saccharomonospora_phage	5.9e-91	38.3

DBSCAN-SWA_277

3902270 : 3903557

uncultured_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_009978180.1\|3902270_3903557_-	signal recognition particle-docking protein FtsY	D6PHS7	uncultured_phage	1.6e-13	36.4

DBSCAN-SWA_278

3908957 : 3910543

Bacillus_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_009978189.1\|3908957_3909809_-	DNA-formamidopyrimidine glycosylase	F8WPX6	Bacillus_phage	2.8e-17	26.1
WP_009978190.1\|3909829_3910543_-	ribonuclease III	A0A2K9R4Y7	Dishui_lake_phycodnavirus	4.5e-21	36.2

DBSCAN-SWA_279

3917496 : 3920178

Mycobacterium_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_011725674.1\|3917496_3918936_+	recombinase family protein	A0A2D1GQ20	Mycobacterium_phage	1.3e-62	37.8
WP_011725675.1\|3919179_3920178_+	ATP-binding protein	A0A2K9R7H3	Dishui_lake_phycodnavirus	1.3e-13	28.0

DBSCAN-SWA_280

3927726 : 3928194

Biomphalaria_virus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_011725682.1\|3927726_3928194_+	NUDIX domain-containing protein	A0A1L6UW58	Biomphalaria_virus	8.6e-05	42.4

DBSCAN-SWA_281

3939812 : 3944776

uncultured_Mediterranean_phage(33.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_003875043.1\|3939812_3940295_-	pantetheine-phosphate adenylyltransferase	A0A1B1IVQ3	uncultured_Mediterranean_phage	1.6e-17	30.6
WP_011725690.1\|3940416_3940971_-	16S rRNA (guanine(966)-N(2))-methyltransferase RsmD	NA	NA	NA	NA
WP_011725691.1\|3940981_3941617_-	vitamin K epoxide reductase family protein	NA	NA	NA	NA
WP_003875040.1\|3941613_3942381_-	DsbA family protein	NA	NA	NA	NA
WP_011725692.1\|3942476_3943598_-	alpha/beta hydrolase	M1PGN2	Moumouvirus	1.4e-32	32.0
WP_009978202.1\|3943987_3944776_+	aldo/keto reductase	A0A2H4PQR8	Staphylococcus_phage	6.1e-51	41.7

DBSCAN-SWA_282

3955453 : 3956137

Pandoravirus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_011725701.1\|3955453_3956137_-	uracil-DNA glycosylase	S4VZ65	Pandoravirus	4.8e-36	40.0

DBSCAN-SWA_283

3964183 : 3964822

Streptomyces_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_009978231.1\|3964183_3964822_-	HU family DNA-binding protein	A0A2P1N0A2	Streptomyces_phage	6.3e-14	45.4

DBSCAN-SWA_284

3973619 : 3975206

Brazilian_cedratvirus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_009978240.1\|3973619_3975206_-	phosphoglycerate dehydrogenase	A0A2R8FDS8	Brazilian_cedratvirus	1.3e-36	36.2

DBSCAN-SWA_285

3986547 : 3987579

Ostreococcus_tauri_virus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_003874997.1\|3986547_3987579_-	6-phosphofructokinase	H8ZJH0	Ostreococcus_tauri_virus	4.0e-10	28.5

DBSCAN-SWA_286

3996582 : 4002752

Ralstonia_phage(50.0%)

tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_011725716.1\|3996582_3998664_-	NAD-dependent DNA ligase LigA	A0A0A8J9A9	Ralstonia_phage	2.0e-101	37.2
WP_003878753.1\|3998718_3999747_-	methionine synthase	NA	NA	NA	NA
WP_023880976.1\|4000496_4001573_-\|tRNA	tRNA 2-thiouridine(34) synthase MnmA	NA	NA	NA	NA
WP_011725718.1\|4001573_4002752_-	cysteine desulfurase	A0A1X7C038	Faustovirus	3.2e-32	27.2

DBSCAN-SWA_287

4026459 : 4027788

Bodo_saltans_virus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_011725740.1\|4026459_4027788_+	deoxyribodipyrimidine photo-lyase	A0A2H4UV63	Bodo_saltans_virus	3.9e-50	29.5

DBSCAN-SWA_288

4034941 : 4035784

Chlorella_virus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_011725746.1\|4034941_4035784_-	ABC transporter ATP-binding protein	Q66093	Chlorella_virus	9.8e-07	26.5

DBSCAN-SWA_289

4040238 : 4042746

Tupanvirus(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_009978314.1\|4040238_4041279_+	NAD(P)-dependent alcohol dehydrogenase	A0A2K9L7I1	Tupanvirus	1.4e-74	42.5
WP_011725751.1\|4041289_4041703_-	DUF3349 domain-containing protein	NA	NA	NA	NA
WP_033722795.1\|4041783_4042746_-	class 1b ribonucleoside-diphosphate reductase subunit beta	R4TBI6	Mycobacterium_phage	4.2e-155	84.6

DBSCAN-SWA_290

4046454 : 4053027

Bacillus_phage(33.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_024636978.1\|4046454_4048620_-	class 1b ribonucleoside-diphosphate reductase subunit alpha	V9VI16	Lactococcus_phage	7.4e-208	51.6
WP_003874934.1\|4048589_4049042_-	class Ib ribonucleoside-diphosphate reductase assembly flavoprotein NrdI	A0A142F1R4	Bacillus_phage	1.7e-13	37.7
WP_003874933.1\|4049084_4049324_-	redoxin NrdH	V5UN81	Mycobacterium_phage	2.0e-21	64.5
WP_033711901.1\|4049854_4050409_-	NAD(P)H-dependent oxidoreductase	A0A2P0ZL77	Lactobacillus_phage	5.4e-06	33.6
WP_011725759.1\|4050502_4051117_+	TetR/AcrR family transcriptional regulator	NA	NA	NA	NA
WP_019732093.1\|4051116_4052160_+	DNA polymerase IV	F1C5A5	Cronobacter_phage	4.7e-19	27.9
WP_009978328.1\|4052094_4053027_-	SDR family oxidoreductase	W8CYX9	Bacillus_phage	4.6e-05	35.9

DBSCAN-SWA_291

4068220 : 4069738

Micromonas_pusilla_virus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_011725767.1\|4068220_4069738_+	Hsp70 family protein	M4R062	Micromonas_pusilla_virus	3.1e-19	29.7

DBSCAN-SWA_292

4085782 : 4087066

Streptococcus_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_023868298.1\|4085782_4087066_-	enolase	A0A1X9I5Z8	Streptococcus_phage	3.4e-67	36.0

DBSCAN-SWA_293

4090191 : 4091768

Diadromus_pulchellus_ascovirus(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_011725781.1\|4090191_4090950_-	SDR family oxidoreductase	F2NZ40	Diadromus_pulchellus_ascovirus	3.8e-18	32.7
WP_009978372.1\|4090946_4091768_-	iron-sulfur cluster-binding domain-containing protein	A0A1D7SNA5	Cyanophage	7.8e-09	39.0

DBSCAN-SWA_294

4097429 : 4097813

Gordonia_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_009978380.1\|4097429_4097813_-	type II toxin-antitoxin system death-on-curing family toxin	A0A1B3AYM0	Gordonia_phage	2.2e-22	51.2

DBSCAN-SWA_295

4101241 : 4101640

uncultured_Caudovirales_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_011725788.1\|4101241_4101640_+	fluoride efflux transporter CrcB	A0A2H4J148	uncultured_Caudovirales_phage	9.6e-05	35.6

DBSCAN-SWA_296

4106155 : 4107631

Microcystis_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_011725793.1\|4106155_4107631_+	YdiU family protein	A0A075BSJ0	Microcystis_phage	4.3e-50	35.2

DBSCAN-SWA_297

4112907 : 4124400

Mycobacterium_phage(20.0%)

transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_033722803.1\|4112907_4114401_-	serine hydrolase	A0A1J0GRK9	Mycobacterium_phage	3.6e-12	28.7
WP_023861022.1\|4114420_4115104_+	M15 family metallopeptidase	NA	NA	NA	NA
WP_011725800.1\|4115130_4115637_+	DUF2505 domain-containing protein	NA	NA	NA	NA
WP_023861021.1\|4115647_4116814_+	glycosyltransferase	A0A1L3KK54	Shahe_endorna-like_virus	2.5e-08	43.8
WP_011725802.1\|4116818_4117544_-	class I SAM-dependent methyltransferase	NA	NA	NA	NA
WP_129560182.1\|4117754_4118003_-	hypothetical protein	NA	NA	NA	NA
WP_011725525.1\|4118270_4119503_-\|transposase	IS256-like element IS1245 family transposase	A0A220NQR7	Corynebacterium_phage	2.5e-112	51.5
WP_011725803.1\|4119593_4119902_-	hypothetical protein	NA	NA	NA	NA
WP_073578835.1\|4121465_4122308_-	DMT family transporter	NA	NA	NA	NA
WP_003874853.1\|4122304_4122814_-	SsrA-binding protein SmpB	W5RAM5	Staphylococcus_phage	2.2e-33	47.7
WP_003874852.1\|4122816_4123710_-	ABC transporter permease	NA	NA	NA	NA
WP_003874851.1\|4123710_4124400_-	cell division ATP-binding protein FtsE	G9BWD6	Planktothrix_phage	7.9e-31	37.1

DBSCAN-SWA_298

4133476 : 4134274

Niemeyer_virus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_011725813.1\|4133476_4134274_+	slipin family protein	A0A0U2UF06	Niemeyer_virus	4.4e-25	28.8

DBSCAN-SWA_299

4182973 : 4183924

Mycobacterium_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_011725850.1\|4182973_4183924_-	alpha/beta hydrolase	A0A249XPN5	Mycobacterium_phage	1.9e-06	28.0

DBSCAN-SWA_300

4191178 : 4193299

Tupanvirus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_031343697.1\|4191178_4193299_+	catalase	A0A2K9L0T1	Tupanvirus	1.5e-141	49.2

DBSCAN-SWA_301

4203989 : 4209865

Tupanvirus(33.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_031343685.1\|4203989_4205132_+	NAD-dependent epimerase/dehydratase family protein	A0A2K9KZK0	Tupanvirus	4.8e-57	39.2
WP_011725866.1\|4205143_4206784_+	carbamoyltransferase	A0A1B1IVF2	uncultured_Mediterranean_phage	1.8e-49	30.1
WP_011725867.1\|4206780_4208271_+	HAD-IIIA family hydrolase	NA	NA	NA	NA
WP_009978544.1\|4208279_4209299_+	glycosyltransferase family 9 protein	NA	NA	NA	NA
WP_011725868.1\|4209295_4209865_+	SIS domain-containing protein	A0A067XQR2	Caulobacter_phage	1.9e-09	30.1

DBSCAN-SWA_302

4212932 : 4214237

Paramecium_bursaria_Chlorella_virus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_011725870.1\|4212932_4214237_+	UDP-glucose/GDP-mannose dehydrogenase family protein	M1I9L6	Paramecium_bursaria_Chlorella_virus	2.7e-27	30.5

DBSCAN-SWA_303

4244403 : 4247655

Catovirus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_011725891.1\|4244403_4247655_-	AMP-binding protein	A0A1V0SBX8	Catovirus	6.7e-11	24.8

DBSCAN-SWA_304

4254362 : 4260925

Bordetella_phage(25.0%)

transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_011725895.1\|4254362_4255310_+	GGDEF domain-containing protein	A0A2D0WBV8	Bordetella_phage	3.1e-09	35.1
WP_011725896.1\|4255361_4255898_+	hypothetical protein	NA	NA	NA	NA
WP_011725897.1\|4255921_4256410_+	glutathione peroxidase	A0A1S7DM81	Molluscum_contagiosum_virus	2.2e-11	35.5
WP_011725898.1\|4256434_4257211_-	DUF3298 domain-containing protein	NA	NA	NA	NA
WP_011725525.1\|4257430_4258663_-\|transposase	IS256-like element IS1245 family transposase	A0A220NQR7	Corynebacterium_phage	2.5e-112	51.5
WP_009978639.1\|4260364_4260925_+	DUF2493 domain-containing protein	A0A222ZMZ5	Mycobacterium_phage	6.9e-17	40.8

DBSCAN-SWA_305

4270215 : 4278869

Mycobacterium_phage(33.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_011725907.1\|4270215_4270488_-	WhiB family transcriptional regulator	A0A2P1JRB7	Mycobacterium_phage	3.1e-07	49.0
WP_033722827.1\|4270923_4273044_-	ATP-dependent DNA helicase UvrD2	A0A1V0SDG5	Indivirus	3.0e-12	21.5
WP_011725909.1\|4273222_4273477_+	mycoredoxin Mrx1	NA	NA	NA	NA
WP_011725910.1\|4273485_4274418_-	NAD(+) diphosphatase	NA	NA	NA	NA
WP_009978654.1\|4274417_4275488_-	potassium channel family protein	NA	NA	NA	NA
WP_011725911.1\|4275578_4278869_-	ATP-dependent helicase	A7KV33	Bacillus_phage	2.8e-09	21.0

DBSCAN-SWA_306

4292731 : 4293532

Natrialba_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_009978675.1\|4292731_4293532_-	ParA family protein	Q8JL10	Natrialba_phage	2.2e-16	33.5

DBSCAN-SWA_307

4297631 : 4301173

Mycobacterium_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_003874607.1\|4297631_4297886_+	WhiB family transcriptional regulator	A0A2P1N2X5	Mycobacterium_phage	1.5e-11	43.9
WP_011725921.1\|4297955_4299455_-	ATPase	NA	NA	NA	NA
WP_003874604.1\|4299483_4299699_-	biotin/lipoyl-binding carrier protein	NA	NA	NA	NA
WP_085976515.1\|4299975_4300050_+	hypothetical protein	NA	NA	NA	NA
WP_011725922.1\|4300366_4301173_-	sigma-70 family RNA polymerase sigma factor	A0A076YQ50	Rhizobium_phage	6.5e-08	26.5

DBSCAN-SWA_308

4304457 : 4305207

Trichoplusia_ni_ascovirus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_011725926.1\|4304457_4305207_-	SDR family oxidoreductase	Q06VL0	Trichoplusia_ni_ascovirus	5.1e-15	31.9

DBSCAN-SWA_309

4337039 : 4341772

Bacillus_phage(66.67%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_003878943.1\|4337039_4338737_-	HAMP domain-containing histidine kinase	W8CYF6	Bacillus_phage	6.5e-18	27.2
WP_007168097.1\|4338795_4339482_-	response regulator transcription factor	W8CYM9	Bacillus_phage	1.6e-39	37.6
WP_009978739.1\|4339562_4340195_-	dTMP kinase	NA	NA	NA	NA
WP_003874564.1\|4340281_4341772_-	adenosylhomocysteinase	S4VPF6	Pandoravirus	4.1e-40	28.6

DBSCAN-SWA_310

4352160 : 4352499

Mycobacterium_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_011725952.1\|4352160_4352499_-	WhiB family transcriptional regulator	A0A2P1CGA4	Mycobacterium_phage	2.4e-28	77.5

DBSCAN-SWA_311

4357461 : 4358538

Enterobacteria_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_011725957.1\|4357461_4358538_-	NDP-sugar synthase	I7I009	Enterobacteria_phage	1.1e-15	26.5

DBSCAN-SWA_312

4363025 : 4375879

Streptococcus_phage(25.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_011725961.1\|4363025_4365164_+	manganese-exporting P-type ATPase CtpC	E4ZFI9	Streptococcus_phage	9.0e-73	31.7
WP_009978767.1\|4365321_4366236_+	class I SAM-dependent methyltransferase	NA	NA	NA	NA
WP_011725962.1\|4366247_4367468_+	CoA transferase	NA	NA	NA	NA
WP_011725963.1\|4367471_4369442_-	protein kinase	A0A285PXP1	Cedratvirus	6.4e-09	28.2
WP_003874536.1\|4369493_4370594_-	phosphate ABC transporter substrate-binding protein PstS	NA	NA	NA	NA
WP_003874535.1\|4370728_4371169_-	response regulator	NA	NA	NA	NA
WP_009978773.1\|4371165_4372773_-	HAMP domain-containing protein	W8CYF6	Bacillus_phage	2.3e-12	24.3
WP_024637041.1\|4372769_4373915_-	SpoIIE family protein phosphatase	NA	NA	NA	NA
WP_003878960.1\|4374169_4375339_-	acyl-CoA dehydrogenase	NA	NA	NA	NA
WP_011725965.1\|4375357_4375879_-	5-(carboxyamino)imidazole ribonucleotide mutase	A0A2P0VNU7	Tetraselmis_virus	7.9e-23	47.7

DBSCAN-SWA_313

4387406 : 4391367

Bacillus_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_041160738.1\|4387406_4388195_-	RNA polymerase sigma factor SigF	A0A218KDJ1	Bacillus_phage	4.1e-15	25.0
WP_003878970.1\|4388191_4388629_-	hypothetical protein	NA	NA	NA	NA
WP_003874516.1\|4389074_4389386_-	hypothetical protein	NA	NA	NA	NA
WP_003874515.1\|4389446_4389830_-	hypothetical protein	NA	NA	NA	NA
WP_009978790.1\|4390026_4391367_-	L-lysine 6-transaminase	A0A1V0SKB7	Klosneuvirus	1.3e-114	45.7

DBSCAN-SWA_314

4403901 : 4405038

Mycobacterium_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_003878975.1\|4403901_4405038_-	PPE family protein	V5UPR1	Mycobacterium_phage	1.8e-08	28.9

DBSCAN-SWA_315

4415114 : 4416695

Streptococcus_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_011725984.1\|4415114_4416695_+	phospho-sugar mutase	A0A1X9I671	Streptococcus_phage	1.1e-43	29.2

DBSCAN-SWA_316

4421802 : 4423050

Corynebacterium_phage(100.0%)

transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_031349784.1\|4421802_4423050_-\|transposase	IS256-like element IS1601 family transposase	A0A220NQR7	Corynebacterium_phage	9.8e-80	41.9

DBSCAN-SWA_317

4426312 : 4427596

Geobacillus_virus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_011725991.1\|4426312_4427596_-	thymidine phosphorylase	A0A0H3UZD4	Geobacillus_virus	4.7e-77	43.4

DBSCAN-SWA_318

4433370 : 4436402

Klosneuvirus(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_009978831.1\|4433370_4434702_+	aspartate aminotransferase family protein	A0A1V0SKB7	Klosneuvirus	4.5e-14	23.4
WP_003874473.1\|4434676_4434928_-	hypothetical protein	NA	NA	NA	NA
WP_011725994.1\|4435142_4436402_+	D-alanyl-D-alanine carboxypeptidase	A0A1P8VVG5	Erythrobacter_phage	2.2e-10	31.7

DBSCAN-SWA_319

4446270 : 4447641

Pandoravirus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_009978841.1\|4446270_4447641_+	bifunctional o-acetylhomoserine/o-acetylserine sulfhydrylase	A0A0B5JD48	Pandoravirus	2.3e-13	25.7

DBSCAN-SWA_320

4450937 : 4452173

Corynebacterium_phage(100.0%)

transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_010948736.1\|4450937_4452173_+\|transposase	IS256-like element IS1311 family transposase	A0A220NQR7	Corynebacterium_phage	2.1e-111	53.2

DBSCAN-SWA_321

4455668 : 4460781

Brazilian_cedratvirus(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_033726039.1\|4455668_4458284_+	FHA domain-containing protein	A0A2R8FG22	Brazilian_cedratvirus	5.3e-27	35.7
WP_031348302.1\|4458321_4460781_+	ATP-binding cassette domain-containing protein	W5SAS9	Pithovirus	9.8e-23	27.6

DBSCAN-SWA_322

4467726 : 4471008

Streptomyces_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_011726008.1\|4467726_4471008_-	DNA polymerase III subunit alpha	A0A1C9LWS4	Streptomyces_phage	2.6e-119	32.3

DBSCAN-SWA_323

4484684 : 4486262

Hokovirus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_023870683.1\|4484684_4486262_-	glutamine-hydrolyzing GMP synthase	A0A1V0SH76	Hokovirus	7.2e-11	26.0

DBSCAN-SWA_324

4495805 : 4497401

Klosneuvirus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_003874394.1\|4495805_4497401_-	IMP dehydrogenase	A0A1V0SHK8	Klosneuvirus	2.6e-85	39.0

DBSCAN-SWA_325

4500661 : 4506484

uncultured_virus(50.0%)

tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_003874400.1\|4500661_4500970_+	WhiB family transcriptional regulator	I6XD27	Mycobacterium_virus	2.6e-10	42.9
WP_011726029.1\|4501012_4501777_+	superoxide dismutase family protein	NA	NA	NA	NA
WP_023862261.1\|4501932_4503132_-	FAD-dependent oxidoreductase	NA	NA	NA	NA
WP_011726032.1\|4503245_4504862_-	chaperonin GroEL	A0A219YK78	uncultured_virus	6.0e-138	51.3
WP_003873391.1\|4504950_4505253_-	co-chaperone GroES	A0A221S3C8	uncultured_virus	3.3e-21	54.8
WP_003879516.1\|4505458_4506484_-\|tRNA	tRNA (adenosine(37)-N6)-threonylcarbamoyltransferase complex transferase subunit TsaD	A0A291ATS8	Pandoravirus	6.7e-34	36.5

DBSCAN-SWA_326

4515108 : 4516983

Paramecium_bursaria_Chlorella_virus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_011726040.1\|4515108_4516983_-	glutamine--fructose-6-phosphate transaminase (isomerizing)	M1H1Z3	Paramecium_bursaria_Chlorella_virus	1.7e-96	36.1

DBSCAN-SWA_327

4525958 : 4532332

Mycobacterium_phage(100.0%)

protease

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_011726048.1\|4525958_4529552_-	type VII secretion protein EccCb	V5UPA0	Mycobacterium_phage	4.9e-63	31.3
WP_033726033.1\|4529681_4531037_+	type VII secretion integral membrane protein EccD	NA	NA	NA	NA
WP_031348252.1\|4531033_4532332_+\|protease	type VII secretion system ESX-4 serine protease mycosin MycP4	V5UPA7	Mycobacterium_phage	3.7e-45	33.8

DBSCAN-SWA_328

4541872 : 4547250

Burkholderia_phage(60.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_003873450.1\|4541872_4542868_+	dTDP-glucose 4,6-dehydratase	I7HTA3	Enterobacteria_phage	9.9e-75	46.5
WP_011726055.1\|4542869_4543475_+	dTDP-4-dehydrorhamnose 3,5-epimerase	I7HJC4	Enterobacteria_phage	1.1e-28	41.3
WP_003873452.1\|4543707_4544832_+	acyltransferase	A9YX16	Burkholderia_phage	1.3e-17	29.3
WP_009979002.1\|4544931_4546077_+	acyltransferase	A9YX16	Burkholderia_phage	2.5e-21	28.9
WP_011726056.1\|4546161_4547250_+	acyltransferase	A9YX16	Burkholderia_phage	6.2e-22	31.3

DBSCAN-SWA_329

4555926 : 4556985

Pacmanvirus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_011726063.1\|4555926_4556985_-	aminotransferase class I/II-fold pyridoxal phosphate-dependent enzyme	A0A1X6WGT4	Pacmanvirus	9.7e-12	26.6

DBSCAN-SWA_330

4560499 : 4561195

Planktothrix_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_009979025.1\|4560499_4561195_+	ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	8.6e-33	43.0

DBSCAN-SWA_331

4568317 : 4568863

Tupanvirus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_003873479.1\|4568317_4568863_-	adenylate kinase	A0A2K9L833	Tupanvirus	1.4e-14	33.8

DBSCAN-SWA_332

4573391 : 4574372

Acanthocystis_turfacea_Chlorella_virus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_009979044.1\|4573391_4574372_+	3-phosphoglycerate dehydrogenase	M1GWB3	Acanthocystis_turfacea_Chlorella_virus	1.4e-20	26.9

DBSCAN-SWA_333

4589077 : 4589968

Microcystis_virus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_011726074.1\|4589077_4589968_-	formylglycine-generating enzyme family protein	A0A7H6	Microcystis_virus	2.4e-19	31.7

DBSCAN-SWA_334

4601389 : 4602829

Catovirus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_011726079.1\|4601389_4602829_-	mycofactocin system GMC family oxidoreductase MftG	A0A1V0S9J5	Catovirus	1.3e-11	26.8

DBSCAN-SWA_335

4609719 : 4610580

Staphylococcus_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_011726085.1\|4609719_4610580_-	aldo/keto reductase	A0A2H4PQR8	Staphylococcus_phage	3.3e-50	41.4

DBSCAN-SWA_336

4615869 : 4619336

Hokovirus(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_003873538.1\|4615869_4617060_-	elongation factor Tu	A0A1V0SGC3	Hokovirus	1.1e-30	27.4
WP_003879424.1\|4617230_4619336_-	elongation factor G	E4ZFJ7	Streptococcus_phage	3.1e-62	26.8

DBSCAN-SWA_337

4627383 : 4636294

Vibrio_phage(33.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_011726094.1\|4627383_4631334_-	DNA-directed RNA polymerase subunit beta'	A0A2I7QNZ7	Vibrio_phage	2.1e-51	25.6
WP_085978600.1\|4631378_4634888_-	DNA-directed RNA polymerase subunit beta	A0A1B1ISA9	uncultured_Mediterranean_phage	7.4e-40	22.7
WP_003873552.1\|4635283_4636294_-	ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	2.8e-24	35.6

DBSCAN-SWA_338

4647014 : 4651197

Micromonas_pusilla_virus(33.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_003879413.1\|4647014_4648349_+	AarF/ABC1/UbiB kinase family protein	G8DDN0	Micromonas_pusilla_virus	1.3e-32	28.3
WP_009979146.1\|4648360_4649266_+	alpha/beta hydrolase	NA	NA	NA	NA
WP_003873564.1\|4649355_4650216_+	methyltransferase domain-containing protein	A0A2K9L4K8	Tupanvirus	1.1e-24	29.1
WP_009979148.1\|4650300_4651197_+	class I SAM-dependent methyltransferase	A0A2I2L5L3	Orpheovirus	9.4e-24	28.9

DBSCAN-SWA_339

4663749 : 4666625

Tupanvirus(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_009979160.1\|4663749_4664772_-	patatin-like phospholipase family protein	A0A2K9L3A4	Tupanvirus	1.3e-05	23.3
WP_003873583.1\|4664772_4665240_-	cyanase	NA	NA	NA	NA
WP_009979163.1\|4665308_4666058_-	methyltransferase domain-containing protein	NA	NA	NA	NA
WP_011726109.1\|4666109_4666625_-	nitroreductase	A0A1V0E011	Clostridioides_phage	2.0e-10	28.5

DBSCAN-SWA_340

4671083 : 4676107

Cafeteria_roenbergensis_virus(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_011726111.1\|4671083_4674386_+	exodeoxyribonuclease V subunit beta	E3T5J8	Cafeteria_roenbergensis_virus	3.5e-07	20.2
WP_033722899.1\|4674382_4676107_+	exodeoxyribonuclease V subunit alpha	A0A0K2FLP8	Brevibacillus_phage	6.9e-15	24.4

DBSCAN-SWA_341

4701964 : 4702834

Mycobacterium_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_009979190.1\|4701964_4702834_-	alpha/beta fold hydrolase	G1DB77	Mycobacterium_phage	1.6e-15	30.3

DBSCAN-SWA_342

4726982 : 4728584

Staphylococcus_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_011726142.1\|4726982_4728584_+	AMP-binding protein	A0A2H4PQM9	Staphylococcus_phage	8.9e-25	24.4

DBSCAN-SWA_343

4742801 : 4743830

Bodo_saltans_virus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_003873653.1\|4742801_4743830_-	NAD-dependent epimerase/dehydratase family protein	A0A2H4UUK0	Bodo_saltans_virus	1.8e-18	26.5

DBSCAN-SWA_344

4762820 : 4767225

Gordonia_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_011726165.1\|4762820_4764941_+	acyltransferase	A0A166XZF2	Gordonia_phage	1.4e-73	33.9
WP_003873686.1\|4765131_4765821_-	SGNH/GDSL hydrolase family protein	NA	NA	NA	NA
WP_023862190.1\|4765911_4767225_-	acyltransferase	A0A2H4JA46	uncultured_Caudovirales_phage	1.1e-15	25.7

DBSCAN-SWA_345

4779513 : 4784281

Tupanvirus(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_003873706.1\|4779513_4780413_+	methyltransferase domain-containing protein	A0A2K9L4K8	Tupanvirus	1.7e-25	30.8
WP_011726173.1\|4780512_4781577_-	acyltransferase family protein	NA	NA	NA	NA
WP_003873708.1\|4781582_4782710_-	SDR family oxidoreductase	NA	NA	NA	NA
WP_003402602.1\|4782761_4782863_-	AURKAIP1/COX24 domain-containing protein	NA	NA	NA	NA
WP_010950195.1\|4782997_4783255_-	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_011726174.1\|4783393_4784281_-	pyrroline-5-carboxylate reductase	A0A1X9I6T5	Streptococcus_phage	1.0e-22	33.1

DBSCAN-SWA_346

4790386 : 4792561

Bacillus_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_003873718.1\|4790386_4791070_-	response regulator transcription factor	W8CYM9	Bacillus_phage	2.6e-42	40.4
WP_085989560.1\|4791331_4792561_-	two-component sensor histidine kinase	W8CYF6	Bacillus_phage	6.2e-26	32.1

DBSCAN-SWA_347

4807821 : 4809567

Tupanvirus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_009979325.1\|4807821_4808688_+	class I SAM-dependent methyltransferase	A0A2K9L4K8	Tupanvirus	2.0e-31	32.9
WP_003873739.1\|4808706_4809567_-	methyltransferase domain-containing protein	A0A2K9L4K8	Tupanvirus	3.4e-31	34.2

DBSCAN-SWA_348

4815587 : 4816985

Erysipelothrix_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_003873752.1\|4815587_4816985_-	dihydrolipoyl dehydrogenase	A0A2K5B2C5	Erysipelothrix_phage	5.5e-47	28.7

DBSCAN-SWA_349

4835761 : 4837387

uncultured_virus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_009979353.1\|4835761_4837387_-	chaperonin GroEL	A0A240F779	uncultured_virus	5.4e-155	56.2

DBSCAN-SWA_350

4843807 : 4845976

Phaeocystis_globosa_virus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_011726205.1\|4843807_4845976_+	AAA family ATPase	R4TQL5	Phaeocystis_globosa_virus	3.1e-36	40.1

DBSCAN-SWA_351

4852134 : 4852443

Gordonia_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_003873790.1\|4852134_4852443_-	DUF3263 domain-containing protein	A0A1B3AZ99	Gordonia_phage	4.2e-08	44.9

DBSCAN-SWA_352

4867489 : 4868257

Gordonia_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_011726220.1\|4867489_4868257_-	SGNH/GDSL hydrolase family protein	A0A160DD06	Gordonia_phage	4.7e-08	34.5

DBSCAN-SWA_353

4874139 : 4876431

Myeloproliferative_sarcoma_virus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_011726224.1\|4874139_4876431_+	protein kinase	Q83745	Myeloproliferative_sarcoma_virus	1.2e-09	28.2

DBSCAN-SWA_354

4901545 : 4906569

Pandoravirus(50.0%)

protease

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_011726241.1\|4901545_4902844_-	adenylosuccinate synthase	A0A291AUF9	Pandoravirus	1.8e-68	35.3
WP_011726242.1\|4902951_4903893_-	histidine phosphatase family protein	NA	NA	NA	NA
WP_011726244.1\|4904189_4904840_+	hypothetical protein	NA	NA	NA	NA
WP_011726245.1\|4904849_4905632_+\|protease	site-2 protease family protein	NA	NA	NA	NA
WP_011726246.1\|4905672_4906569_+	cation transporter	A0A1V0SED0	Indivirus	2.0e-05	32.5

DBSCAN-SWA_355

4912879 : 4917795

Prochlorococcus_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_011726253.1\|4912879_4913419_-	orotate phosphoribosyltransferase	Q58MW1	Prochlorococcus_phage	3.7e-15	44.2
WP_011726254.1\|4913405_4914179_-	SDR family oxidoreductase	NA	NA	NA	NA
WP_003873856.1\|4914235_4915108_-	hypothetical protein	NA	NA	NA	NA
WP_003873857.1\|4915248_4917795_-	ATP-dependent chaperone ClpB	K4FB40	Cronobacter_phage	4.0e-120	36.5

DBSCAN-SWA_356

4927756 : 4936383

uncultured_virus(33.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_011726263.1\|4927756_4932055_-	AAA family ATPase	A0A218MLZ2	uncultured_virus	1.5e-13	33.3
WP_003873870.1\|4932197_4932593_-	MerR family transcriptional regulator	NA	NA	NA	NA
WP_003879233.1\|4932592_4933771_-	molecular chaperone DnaJ	A0A0P0YMJ9	Yellowstone_lake_phycodnavirus	3.6e-15	27.4
WP_011726264.1\|4933831_4934515_-	nucleotide exchange factor GrpE	NA	NA	NA	NA
WP_009979480.1\|4934511_4936383_-	molecular chaperone DnaK	A0A0N9QXN8	Chrysochromulina_ericina_virus	1.9e-143	50.3

DBSCAN-SWA_357

4952335 : 4955819

Enterobacteria_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_003879222.1\|4952335_4953211_-	glucose-1-phosphate thymidylyltransferase RfbA	I7I009	Enterobacteria_phage	2.3e-91	55.6
WP_011726273.1\|4953238_4953613_-	nuclear transport factor 2 family protein	NA	NA	NA	NA
WP_023884766.1\|4953642_4954398_-	maleylpyruvate isomerase family mycothiol-dependent enzyme	NA	NA	NA	NA
WP_023862135.1\|4954493_4955819_-	UDP-glucose/GDP-mannose dehydrogenase family protein	A0A127AXI2	Bacillus_phage	5.7e-70	36.7

DBSCAN-SWA_358

4962633 : 4963814

Saccharomonospora_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_003873894.1\|4962633_4963206_-	dCTP deaminase	I4AZP2	Saccharomonospora_phage	1.3e-79	77.4
WP_023862132.1\|4963235_4963814_-	hypothetical protein	A0A1J0MBM2	Mycobacterium_phage	1.1e-20	45.7

DBSCAN-SWA_359

4990915 : 4992322

Mycobacterium_phage(100.0%)

protease

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_011726295.1\|4990915_4992322_-\|protease	type VII secretion system ESX-3 serine protease mycosin MycP3	V5UPA7	Mycobacterium_phage	1.0e-69	40.2

DBSCAN-SWA_360

5002800 : 5004633

Mycobacterium_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_085989582.1\|5002800_5004633_-	type VII secretion system ESX-3 AAA family ATPase EccA3	V5UQM2	Mycobacterium_phage	3.9e-101	41.6

DBSCAN-SWA_361

5024453 : 5026139

Staphylococcus_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_011726316.1\|5024453_5026139_-	acyl-CoA synthetase	A0A2H4PQM9	Staphylococcus_phage	7.9e-24	27.9

DBSCAN-SWA_362

5041895 : 5043836

Paramecium_bursaria_Chlorella_virus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_009979614.1\|5041895_5043836_+	fumarate reductase/succinate dehydrogenase flavoprotein subunit	M1HTN0	Paramecium_bursaria_Chlorella_virus	2.9e-22	27.6

DBSCAN-SWA_363

5062309 : 5069344

Tupanvirus(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_011726336.1\|5062309_5064106_-	GMC family oxidoreductase	A0A2I2L3D3	Orpheovirus	3.2e-31	26.3
WP_011726337.1\|5064325_5065780_-	catalase	A0A2K9L0T1	Tupanvirus	2.0e-84	42.7
WP_011726338.1\|5065805_5067263_-	catalase	A0A2K9L0T1	Tupanvirus	6.5e-91	42.7
WP_009979635.1\|5067342_5067642_-	hypothetical protein	NA	NA	NA	NA
WP_142386429.1\|5067636_5067819_+	hypothetical protein	NA	NA	NA	NA
WP_024636874.1\|5068189_5069344_+	NAD-dependent formate dehydrogenase	M1H214	Paramecium_bursaria_Chlorella_virus	2.0e-18	32.1

DBSCAN-SWA_364

5073383 : 5075030

Micromonas_sp._RCC1109_virus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_009979643.1\|5073383_5075030_-	acetolactate synthase large subunit	E5EQ70	Micromonas_sp._RCC1109_virus	7.5e-35	24.3

DBSCAN-SWA_365

5090531 : 5095724

Hepacivirus(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_009979659.1\|5090531_5092061_-	long-chain fatty acid--CoA ligase	Q75ZG1	Hepacivirus	7.2e-32	29.4
WP_024637113.1\|5092148_5092934_-	crotonase/enoyl-CoA hydratase family protein	NA	NA	NA	NA
WP_011726348.1\|5093073_5094483_-	wax ester/triacylglycerol synthase family O-acyltransferase	NA	NA	NA	NA
WP_003874080.1\|5094527_5095724_-	alpha/beta hydrolase	A0A088FQA2	Mycobacterium_phage	6.6e-49	40.1

DBSCAN-SWA_366

5123940 : 5129194

Klosneuvirus(100.0%)

holin

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_011726364.1\|5123940_5125929_+	peptidase M13	A0A1V0SHG2	Klosneuvirus	3.2e-80	27.7
WP_011726365.1\|5125962_5126478_-	DNA starvation/stationary phase protection protein	NA	NA	NA	NA
WP_024637103.1\|5126625_5127501_-	LysR family transcriptional regulator	NA	NA	NA	NA
WP_031347595.1\|5127682_5129194_-\|holin	choline dehydrogenase	A0A1V0SI18	Klosneuvirus	7.3e-53	30.4

DBSCAN-SWA_367

5141663 : 5142317

Mycobacterium_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_011726373.1\|5141663_5142317_-	O-methyltransferase	S5YRC3	Mycobacterium_phage	6.6e-43	47.8

DBSCAN-SWA_368

5168940 : 5188902

Corynebacterium_phage(25.0%)

transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_009978620.1\|5168940_5170527_-	long-chain-fatty-acid--CoA ligase	A0A2H4PQM9	Staphylococcus_phage	2.6e-32	27.3
WP_003874167.1\|5171396_5171837_-	SRPBCC family protein	NA	NA	NA	NA
WP_023879447.1\|5171880_5172366_-	acyl-CoA thioesterase	NA	NA	NA	NA
WP_033721277.1\|5172380_5173493_+	alcohol dehydrogenase catalytic domain-containing protein	A0A0K0KVL7	Prochlorococcus_phage	3.1e-32	29.9
WP_009979740.1\|5173586_5173835_+	hypothetical protein	NA	NA	NA	NA
WP_080516369.1\|5173839_5176800_+	ribbon-helix-helix protein, CopG family	A0A2I5ARD8	Synechococcus_phage	8.2e-16	26.6
WP_009979742.1\|5176871_5177468_+	hypothetical protein	NA	NA	NA	NA
WP_100069961.1\|5177584_5178331_+	nucleotidyl transferase AbiEii/AbiGii toxin family protein	NA	NA	NA	NA
WP_029248649.1\|5178361_5179819_+	type I restriction-modification system subunit M	A0A1V0SLK8	Klosneuvirus	1.5e-31	28.7
WP_081216290.1\|5180497_5180995_+	hypothetical protein	NA	NA	NA	NA
WP_080687450.1\|5180991_5181396_-	hypothetical protein	NA	NA	NA	NA
WP_011725525.1\|5181322_5182555_+\|transposase	IS256-like element IS1245 family transposase	A0A220NQR7	Corynebacterium_phage	2.5e-112	51.5
WP_011726397.1\|5182818_5183520_-	GntR family transcriptional regulator	NA	NA	NA	NA
WP_011726398.1\|5183743_5184622_-	formylglycine-generating enzyme family protein	A0A075BSL8	Microcystis_phage	3.6e-20	29.1
WP_085989561.1\|5185454_5186715_+\|transposase	IS3 family transposase	Q8W6R2	Burkholderia_virus	1.9e-70	53.9
WP_011725525.1\|5187669_5188902_-\|transposase	IS256-like element IS1245 family transposase	A0A220NQR7	Corynebacterium_phage	2.5e-112	51.5

DBSCAN-SWA_369

5206626 : 5208141

Stenotrophomonas_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_011726421.1\|5206626_5208141_+	pyruvate, phosphate dikinase	A0A2D2W2B1	Stenotrophomonas_phage	4.1e-72	39.7

DBSCAN-SWA_370

5225546 : 5228896

Catovirus(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_011726438.1\|5225546_5227286_-	AMP-binding protein	A0A1V0SBX8	Catovirus	5.5e-12	22.6
WP_011726439.1\|5227282_5228896_-	acyl--CoA ligase	A0A2H4PQM9	Staphylococcus_phage	1.4e-25	29.9

DBSCAN-SWA_371

5238083 : 5238833

Trichoplusia_ni_ascovirus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_011726450.1\|5238083_5238833_-	3-oxoacyl-ACP reductase FabG	Q06VL0	Trichoplusia_ni_ascovirus	6.9e-20	33.2

DBSCAN-SWA_372

5242640 : 5243901

Burkholderia_virus(100.0%)

transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_085989545.1\|5242640_5243901_+\|transposase	IS3 family transposase	Q8W6R2	Burkholderia_virus	7.2e-70	52.2

DBSCAN-SWA_373

5248043 : 5254658

Staphylococcus_phage(33.33%)

transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_024637249.1\|5248043_5249579_-	acyl-CoA synthetase	A0A2H4PQU7	Staphylococcus_phage	1.6e-39	31.8
WP_011726459.1\|5249585_5249990_-	SCP2 sterol-binding domain-containing protein	NA	NA	NA	NA
WP_011726460.1\|5250165_5251242_-	ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	1.9e-23	35.1
WP_033722977.1\|5251506_5252076_+	TetR/AcrR family transcriptional regulator	NA	NA	NA	NA
WP_033722984.1\|5252128_5253142_+	acyl dehydratase	NA	NA	NA	NA
WP_011725525.1\|5253425_5254658_+\|transposase	IS256-like element IS1245 family transposase	A0A220NQR7	Corynebacterium_phage	2.5e-112	51.5

DBSCAN-SWA_374

5268954 : 5270187

Corynebacterium_phage(100.0%)

transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_011725525.1\|5268954_5270187_+\|transposase	IS256-like element IS1245 family transposase	A0A220NQR7	Corynebacterium_phage	2.5e-112	51.5

DBSCAN-SWA_375

5273202 : 5273949

Mollivirus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_011726476.1\|5273202_5273949_-	SDR family oxidoreductase	A0A0M4JSW6	Mollivirus	1.1e-12	28.2

DBSCAN-SWA_376

5287616 : 5288357

Trichoplusia_ni_ascovirus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_003874189.1\|5287616_5288357_-	glucose 1-dehydrogenase	Q06VL0	Trichoplusia_ni_ascovirus	9.2e-17	31.4

DBSCAN-SWA_377

5308782 : 5310099

Cotesia_sesamiae_Mombasa_bracovirus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_011726495.1\|5308782_5310099_-	cytochrome P450	I6WI04	Cotesia_sesamiae_Mombasa_bracovirus	6.4e-21	23.8

DBSCAN-SWA_378

5318591 : 5319197

Human_cytomegalovirus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_011726502.1\|5318591_5319197_-	GNAT family N-acetyltransferase	C5MKY6	Human_cytomegalovirus	1.1e-20	32.5

DBSCAN-SWA_379

5326099 : 5329052

Staphylococcus_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_011726509.1\|5326099_5326942_+	ATP-binding cassette domain-containing protein	A0A2H4PQG7	Staphylococcus_phage	2.2e-14	25.5
WP_011726510.1\|5326931_5327750_+	ABC transporter permease	NA	NA	NA	NA
WP_011726511.1\|5327984_5329052_+	esterase family protein	A0A2I6B0H1	Macacine_betaherpesvirus	3.6e-123	67.4

DBSCAN-SWA_380

5333141 : 5334227

uncultured_Mediterranean_phage(100.0%)

protease

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_024636737.1\|5333141_5334227_-\|protease	serine protease	A0A1B1IT49	uncultured_Mediterranean_phage	9.7e-07	24.0

DBSCAN-SWA_381

5348378 : 5350373

Gordonia_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_011726522.1\|5348378_5350373_-	acyltransferase	A0A166XZF2	Gordonia_phage	2.2e-36	32.7

DBSCAN-SWA_382

5362682 : 5374368

Tupanvirus(25.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_011726529.1\|5362682_5364299_+	AMP-binding protein	A0A2K9KZV5	Tupanvirus	3.5e-05	24.2
WP_011726530.1\|5364300_5365074_+	SDR family oxidoreductase	NA	NA	NA	NA
WP_009979863.1\|5365082_5366225_-	NDMA-dependent alcohol dehydrogenase	E3SJ82	Synechococcus_phage	5.2e-27	27.5
WP_011726531.1\|5366310_5366805_-	SRPBCC family protein	NA	NA	NA	NA
WP_011726532.1\|5366891_5367263_+	nuclear transport factor 2 family protein	NA	NA	NA	NA
WP_029245110.1\|5367306_5367528_+	hypothetical protein	NA	NA	NA	NA
WP_033722992.1\|5367960_5372796_+	cation-translocating P-type ATPase	M1HX51	Paramecium_bursaria_Chlorella_virus	2.5e-38	26.8
WP_033722993.1\|5372802_5374368_-	AMP-binding protein	A0A2H4PQM9	Staphylococcus_phage	1.3e-25	25.4

DBSCAN-SWA_383

5396519 : 5398808

uncultured_virus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_011726558.1\|5396519_5398808_+	copper-translocating P-type ATPase	A0A218MNH6	uncultured_virus	1.9e-81	34.7

DBSCAN-SWA_384

5424526 : 5425420

Prochlorococcus_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_011726574.1\|5424526_5425420_-	fructose bisphosphate aldolase	A0A0K0KVJ8	Prochlorococcus_phage	3.2e-08	28.6

DBSCAN-SWA_385

5443679 : 5446006

Mycobacterium_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_009979957.1\|5443679_5445167_-	type VII secretion protein EccB	V5UN45	Mycobacterium_phage	2.6e-71	36.7
WP_033724977.1\|5445169_5446006_-	DUF4226 domain-containing protein	G9FHI5	Rhodococcus_phage	8.2e-14	39.2

DBSCAN-SWA_386

5453894 : 5455337

Mycobacterium_phage(100.0%)

tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_011726591.1\|5453894_5455337_-\|tRNA	CCA tRNA nucleotidyltransferase	A0A249XS88	Mycobacterium_phage	3.1e-61	36.9

DBSCAN-SWA_387

5465652 : 5467013

Orpheovirus(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_031344939.1\|5465652_5466663_+	thioredoxin-disulfide reductase	A0A2I2L5E1	Orpheovirus	2.8e-69	48.9
WP_011726596.1\|5466659_5467013_+	thioredoxin	A0A1J0GW78	Streptomyces_phage	2.5e-25	57.7

DBSCAN-SWA_388

5470419 : 5471412

Natrialba_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_080516406.1\|5470419_5471412_-	ParA family protein	Q8JL10	Natrialba_phage	1.6e-24	33.9

Anti-CRISPR protein detection

Acr_ID: NC_008595.1|WP_011725555.1|3718860_3719211_-|OB-fold-nucleic-acid-binding-domain-containing-protein

Click the colored protein region to show detailed information

Acr ID

Acr position

Acr size

Homology with known anti

Neighbor HTH/AcRanker

Neighbor Aca

In prophage

Protospacer in prophage

NC_008595.1|WP_011725555.1|3718860_3719211_-|OB-fold-nucleic-acid-binding-domain-containing-protein

3718860_3719211_-

116 aa aa

3670517-3722795

yes

CRISPR ID	CRISPR type	Spacer info	Spacer location	Spacer length	Protospacer location	Mismatch
NC_008595_7	Orphan	7.1\|3625457\|29\|NC_008595\|CRISPRCasFinder	3625457-3625485	29	3699816-3699788	2

1. spacer 7.1|3625457|29|NC_008595|CRISPRCasFinder matches to NC_008595 position: 3699816-3699788, mismatch: 2

tgcgccgctcctcctcatcgcttcgctct	CRISPR spacer
tgcgacgctcctcctcatcgctgcgctct	Protospacer
**** ***************** ******

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. NC_008595

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CRISPR-Cas detection and classification

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Click the colored protein region to show detailed information

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Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection

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