CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NC_008785	Burkholderia mallei SAVP1 chromosome I, complete sequence	0 crisprs	cas3,DEDDh,DinG,csa3	0	0	10	0
NC_008784	Burkholderia mallei SAVP1 chromosome II, complete sequence	3 crisprs	csa3,cas3	0	0	2	0

Results visualization

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CRISPR-Cas detection and classification

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

14694 : 60727

Leptospira_phage(33.33%)

plate,transposase

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_038802950.1\|14694_15814_+\|transposase	IS3 family transposase	S5WIU1	Leptospira_phage	3.6e-49	39.5
WP_011204166.1\|15926_16058_-	hypothetical protein	NA	NA	NA	NA
WP_004196846.1\|16041_16239_-	hypothetical protein	NA	NA	NA	NA
WP_004196848.1\|16261_17668_+	amino acid permease	NA	NA	NA	NA
WP_004551036.1\|17981_18317_-	c-type cytochrome	NA	NA	NA	NA
WP_004196853.1\|18343_19144_-	BON domain-containing protein	NA	NA	NA	NA
WP_004196857.1\|19162_19741_-	SIS domain-containing protein	NA	NA	NA	NA
WP_011204167.1\|19863_20346_-	YraN family protein	NA	NA	NA	NA
WP_004196861.1\|20344_21232_+	16S rRNA (cytidine(1402)-2'-O)-methyltransferase	NA	NA	NA	NA
WP_004191998.1\|21326_22790_+\|transposase	IS1182-like element ISBma2 family transposase	A0A1X9I5T2	Streptococcus_phage	8.8e-80	38.6
WP_004198058.1\|22999_24262_-	Hsp70 family protein	NA	NA	NA	NA
WP_004198059.1\|24859_25465_-	nitroreductase family protein	NA	NA	NA	NA
WP_004198060.1\|25426_26002_+	hypothetical protein	NA	NA	NA	NA
WP_004198061.1\|25961_27245_-	MFS transporter	NA	NA	NA	NA
WP_004198062.1\|27403_28048_+	TetR/AcrR family transcriptional regulator	NA	NA	NA	NA
WP_080516879.1\|28038_28389_+	hypothetical protein	NA	NA	NA	NA
WP_004198063.1\|28385_29009_+	DUF1415 domain-containing protein	NA	NA	NA	NA
WP_004198065.1\|29093_29990_-	SAM-dependent methyltransferase	NA	NA	NA	NA
WP_004198067.1\|30117_31254_-	class I SAM-dependent methyltransferase	NA	NA	NA	NA
WP_011204169.1\|31250_31466_-	hypothetical protein	NA	NA	NA	NA
WP_004185303.1\|31610_32729_-	acyltransferase	NA	NA	NA	NA
WP_004199981.1\|32727_33138_+	hypothetical protein	NA	NA	NA	NA
WP_011204170.1\|33131_33674_-	hypothetical protein	NA	NA	NA	NA
WP_009922408.1\|34105_34201_-	hypothetical protein	NA	NA	NA	NA
WP_004204896.1\|34239_36405_+	peptidase	A0A0P0IY26	Acinetobacter_phage	1.9e-46	27.1
WP_071893038.1\|36986_37385_+	hypothetical protein	NA	NA	NA	NA
WP_011205259.1\|37427_37697_+	hypothetical protein	NA	NA	NA	NA
WP_004204906.1\|37799_38030_+	hypothetical protein	NA	NA	NA	NA
WP_012729786.1\|38263_38620_-	hypothetical protein	NA	NA	NA	NA
WP_004199991.1\|38645_39914_+	HlyD family efflux transporter periplasmic adaptor subunit	NA	NA	NA	NA
WP_004199993.1\|39928_42190_+	peptidase domain-containing ABC transporter	W8CYL7	Bacillus_phage	4.2e-36	27.7
WP_004199995.1\|42186_43635_+	TolC family protein	NA	NA	NA	NA
WP_004199997.1\|43845_44802_-	hypothetical protein	NA	NA	NA	NA
WP_004527832.1\|44813_45779_+	M15 family metallopeptidase	NA	NA	NA	NA
WP_011204174.1\|45796_46075_+	hypothetical protein	NA	NA	NA	NA
WP_004200001.1\|46050_49944_+	type VI secretion system membrane subunit TssM	NA	NA	NA	NA
WP_004200003.1\|49940_50930_+	type VI secretion system-associated protein TagF	NA	NA	NA	NA
WP_004185296.1\|50934_51867_+	OmpA family protein	NA	NA	NA	NA
WP_004200005.1\|52065_53187_-	type VI secretion system protein TssA	NA	NA	NA	NA
WP_004200009.1\|53276_55970_-	type VI secretion system ATPase TssH	A0A223W0B1	Agrobacterium_phage	9.5e-88	31.5
WP_004204910.1\|56003_57104_-\|plate	type VI secretion system baseplate subunit TssG	NA	NA	NA	NA
WP_076839014.1\|57067_58894_-\|plate	type VI secretion system baseplate subunit TssF	NA	NA	NA	NA
WP_011205263.1\|58985_59498_-\|plate	type VI secretion system baseplate subunit TssE	NA	NA	NA	NA
WP_038802950.1\|59606_60727_-\|transposase	IS3 family transposase	S5WIU1	Leptospira_phage	3.6e-49	39.5

DBSCAN-SWA_2

499640 : 508877

Hokovirus(16.67%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_004194034.1\|499640_501593_+	molecular chaperone DnaK	A0A1V0SH73	Hokovirus	2.7e-148	49.2
WP_004194374.1\|501859_502990_+	molecular chaperone DnaJ	A0A1V0SBY2	Catovirus	2.9e-22	27.6
WP_004194350.1\|503023_505030_+	bifunctional anthranilate synthase component I family protein/class IV aminotransferase	S4VT78	Pandoravirus	9.7e-53	35.0
WP_004194137.1\|505205_506021_-	3-methyl-2-oxobutanoate hydroxymethyltransferase	A0A0N7HVJ8	Ostreococcus_lucimarinus_virus	8.8e-37	33.3
WP_004194274.1\|506085_506769_-	deoxynucleoside kinase	A0A249XZR7	Enterococcus_phage	2.6e-05	26.0
WP_004194373.1\|506765_507293_-	2-amino-4-hydroxy-6- hydroxymethyldihydropteridine diphosphokinase	NA	NA	NA	NA
WP_004194112.1\|507329_508877_-	polynucleotide adenylyltransferase PcnB	H7BUW3	unidentified_phage	4.3e-24	31.2

DBSCAN-SWA_3

554787 : 615674

Leptospira_phage(13.33%)

protease,transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_038802950.1\|554787_555907_+\|transposase	IS3 family transposase	S5WIU1	Leptospira_phage	3.6e-49	39.5
WP_071810810.1\|556074_556293_+	hypothetical protein	NA	NA	NA	NA
WP_004185496.1\|556490_557000_+	DUF192 domain-containing protein	A0A1B1IUW8	uncultured_Mediterranean_phage	5.5e-13	41.2
WP_004197486.1\|557300_559415_+	elongation factor G	E4ZFJ7	Streptococcus_phage	5.8e-56	26.7
WP_009936593.1\|559696_559903_+	hypothetical protein	NA	NA	NA	NA
WP_038796688.1\|560583_562062_+	hypothetical protein	NA	NA	NA	NA
WP_004186341.1\|562606_563452_-	aldo/keto reductase	A0A2H4PQR8	Staphylococcus_phage	3.4e-23	29.9
WP_004185897.1\|563620_564367_+	GntR family transcriptional regulator	NA	NA	NA	NA
WP_004197492.1\|565082_566444_+	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_004185818.1\|566983_568423_+	DHA2 family efflux MFS transporter permease subunit	NA	NA	NA	NA
WP_004200476.1\|569049_570324_+	EAL domain-containing protein	NA	NA	NA	NA
WP_004185918.1\|570455_571061_-	class I SAM-dependent methyltransferase	NA	NA	NA	NA
WP_011204108.1\|571360_571522_-	hypothetical protein	NA	NA	NA	NA
WP_004186428.1\|571600_572623_-	2-dehydropantoate 2-reductase	NA	NA	NA	NA
WP_004185585.1\|572638_573166_-	DUF962 domain-containing protein	NA	NA	NA	NA
WP_004185910.1\|573250_574006_+	Crp/Fnr family transcriptional regulator	NA	NA	NA	NA
WP_004185841.1\|577493_578072_-	superoxide dismutase	Q56AR7	Bacillus_thuringiensis_phage	1.1e-44	44.7
WP_004197496.1\|578268_579651_-	exodeoxyribonuclease VII large subunit	A0A1B3AYB4	Gordonia_phage	6.1e-30	27.5
WP_004200482.1\|579645_579876_+	hypothetical protein	NA	NA	NA	NA
WP_004555967.1\|580108_581137_+	tetraacyldisaccharide 4'-kinase	NA	NA	NA	NA
WP_004196455.1\|581117_581324_+	Trm112 family protein	NA	NA	NA	NA
WP_004185994.1\|581497_582289_+	3-deoxy-manno-octulosonate cytidylyltransferase	NA	NA	NA	NA
WP_009929233.1\|582309_582507_+	hypothetical protein	NA	NA	NA	NA
WP_004185840.1\|582497_583160_+	adenylate kinase	NA	NA	NA	NA
WP_004191998.1\|583275_584739_+\|transposase	IS1182-like element ISBma2 family transposase	A0A1X9I5T2	Streptococcus_phage	8.8e-80	38.6
WP_004196460.1\|584842_585046_-	cold-shock protein	A0A2H4N7Y6	Lake_Baikal_phage	6.8e-23	81.8
WP_004194131.1\|585578_585893_+\|protease	ATP-dependent Clp protease adapter ClpS	A0A218MMY6	uncultured_virus	4.4e-13	44.6
WP_004196461.1\|585889_588190_+\|protease	ATP-dependent Clp protease ATP-binding subunit ClpA	A0A223W0B1	Agrobacterium_phage	5.1e-167	42.1
WP_096325460.1\|589008_590129_-\|transposase	IS3 family transposase	S5WIU1	Leptospira_phage	3.6e-49	39.5
WP_004190070.1\|590159_590666_-	cyclic pyranopterin monophosphate synthase MoaC	NA	NA	NA	NA
WP_076804428.1\|590812_592537_+	M48 family metallopeptidase	NA	NA	NA	NA
WP_004189390.1\|592858_593482_-	DUF2946 family protein	NA	NA	NA	NA
WP_004189905.1\|593474_594509_-	alpha/beta fold hydrolase	NA	NA	NA	NA
WP_004189144.1\|594528_594975_-	nuclear transport factor 2 family protein	NA	NA	NA	NA
WP_004197552.1\|595106_596147_-	lipopolysaccharide heptosyltransferase II	NA	NA	NA	NA
WP_004197553.1\|596274_596472_-	zinc-finger domain-containing protein	NA	NA	NA	NA
WP_004188924.1\|596537_597461_-	branched-chain amino acid transaminase	NA	NA	NA	NA
WP_004189945.1\|597682_598432_+	branched-chain amino acid ABC transporter permease	NA	NA	NA	NA
WP_004189842.1\|598428_598752_+	AzlD domain-containing protein	NA	NA	NA	NA
WP_004189839.1\|599018_600212_+	phosphoglycerate kinase	NA	NA	NA	NA
WP_004190063.1\|600292_600568_+	hypothetical protein	NA	NA	NA	NA
WP_004188973.1\|600546_601983_+	pyruvate kinase	NA	NA	NA	NA
WP_004190157.1\|602263_603328_+	fructose-bisphosphate aldolase class II	NA	NA	NA	NA
WP_004189256.1\|603517_604408_+	phosphoribosylaminoimidazolesuccinocarboxamide synthase	A0A0M4JBD3	Mollivirus	3.3e-53	37.8
WP_004188932.1\|604443_604962_+	5-(carboxyamino)imidazole ribonucleotide mutase	NA	NA	NA	NA
WP_004190104.1\|605041_606238_+	5-(carboxyamino)imidazole ribonucleotide synthase	NA	NA	NA	NA
WP_004188980.1\|606249_607275_+	threonylcarbamoyl-AMP synthase	A0A291ATS8	Pandoravirus	1.9e-41	40.2
WP_004189788.1\|607522_608662_-	acylhydrolase	NA	NA	NA	NA
WP_004201777.1\|610023_611475_-	D-alanyl-D-alanine carboxypeptidase/D-alanyl-D-alanine-endopeptidase	NA	NA	NA	NA
WP_004189255.1\|611742_612405_+	response regulator	NA	NA	NA	NA
WP_004190128.1\|612408_613725_+	HAMP domain-containing protein	W8CYF6	Bacillus_phage	1.9e-20	29.6
WP_004526224.1\|614186_615674_+\|protease	DegQ family serine endoprotease	A0A1B1IT49	uncultured_Mediterranean_phage	2.0e-26	32.1

DBSCAN-SWA_4

1344638 : 1368469

uncultured_Caudovirales_phage(50.0%)

plate,transposase,coat

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_004192127.1\|1344638_1346489_+\|plate	type VI secretion system baseplate subunit TssF	NA	NA	NA	NA
WP_004193292.1\|1346516_1347932_-	hypothetical protein	NA	NA	NA	NA
WP_004193592.1\|1347955_1348222_-	PAAR domain-containing protein	NA	NA	NA	NA
WP_004192367.1\|1348481_1348709_-	hypothetical protein	NA	NA	NA	NA
WP_004191109.1\|1348742_1351550_+	type VI secretion system tip protein VgrG	A0A2H4JCD4	uncultured_Caudovirales_phage	6.8e-28	25.1
WP_004192570.1\|1351552_1352386_+	DUF4123 domain-containing protein	NA	NA	NA	NA
WP_038802950.1\|1352619_1353740_-\|transposase	IS3 family transposase	S5WIU1	Leptospira_phage	3.6e-49	39.5
WP_004193365.1\|1353834_1354227_+	hypothetical protein	NA	NA	NA	NA
WP_004193170.1\|1354486_1355800_+	divalent metal cation transporter	NA	NA	NA	NA
WP_011203888.1\|1355848_1356025_+	hypothetical protein	NA	NA	NA	NA
WP_011203889.1\|1356316_1356571_-	hypothetical protein	NA	NA	NA	NA
WP_004552605.1\|1356655_1356964_+	lipoprotein	NA	NA	NA	NA
WP_004193855.1\|1357216_1357498_-	H-NS histone family protein	NA	NA	NA	NA
WP_009937836.1\|1357497_1357758_-	hypothetical protein	NA	NA	NA	NA
WP_004192394.1\|1357965_1358958_-	hydrolase	NA	NA	NA	NA
WP_004196700.1\|1359002_1360199_-	MFS transporter	NA	NA	NA	NA
WP_009920897.1\|1360354_1360492_-	hypothetical protein	NA	NA	NA	NA
WP_004196705.1\|1360705_1361599_+	LysR family transcriptional regulator	NA	NA	NA	NA
WP_004531175.1\|1361936_1362158_+	hypothetical protein	NA	NA	NA	NA
WP_004542449.1\|1362243_1362429_+	hypothetical protein	NA	NA	NA	NA
WP_004192149.1\|1362415_1362961_+\|coat	spore coat protein U domain-containing protein	NA	NA	NA	NA
WP_004191870.1\|1363013_1363574_+\|coat	spore coat protein U domain-containing protein	NA	NA	NA	NA
WP_004526783.1\|1363650_1364175_+\|coat	spore coat protein U domain-containing protein	NA	NA	NA	NA
WP_004191504.1\|1364192_1365032_+	molecular chaperone	NA	NA	NA	NA
WP_011807694.1\|1365139_1367488_+	fimbrial biogenesis outer membrane usher protein	NA	NA	NA	NA
WP_004196717.1\|1367503_1368469_+\|coat	spore coat protein U domain-containing protein	NA	NA	NA	NA

DBSCAN-SWA_5

1453658 : 1504475

Leptospira_phage(42.86%)

transposase,tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_004266640.1\|1453658_1454168_+\|transposase	IS3 family transposase	NA	NA	NA	NA
WP_011203911.1\|1455196_1455535_-	hypothetical protein	NA	NA	NA	NA
WP_004192661.1\|1455613_1457986_-	penicillin acylase family protein	NA	NA	NA	NA
WP_038802950.1\|1459352_1460473_-\|transposase	IS3 family transposase	S5WIU1	Leptospira_phage	3.6e-49	39.5
WP_004191362.1\|1460999_1462553_+	collagen-like triple helix repeat-containing protein	NA	NA	NA	NA
WP_004192734.1\|1462602_1463868_+	lipoprotein	NA	NA	NA	NA
WP_011203914.1\|1464018_1465698_+	ShlB/FhaC/HecB family hemolysin secretion/activation protein	NA	NA	NA	NA
WP_009920703.1\|1465822_1465954_+	hypothetical protein	NA	NA	NA	NA
WP_004193599.1\|1465941_1466403_+	DUF2147 domain-containing protein	NA	NA	NA	NA
WP_004191720.1\|1466639_1467050_-\|transposase	transposase	NA	NA	NA	NA
WP_004526858.1\|1467021_1467240_-	hypothetical protein	NA	NA	NA	NA
WP_004550551.1\|1467244_1468342_-	cell division protein ZapE	NA	NA	NA	NA
WP_004191219.1\|1468448_1469879_-	dihydrolipoyl dehydrogenase	A0A2K5B2C5	Erysipelothrix_phage	1.9e-42	27.8
WP_004192735.1\|1469978_1471253_-	2-oxoglutarate dehydrogenase complex dihydrolipoyllysine-residue succinyltransferase	NA	NA	NA	NA
WP_004191889.1\|1471380_1474245_-	2-oxoglutarate dehydrogenase E1 component	NA	NA	NA	NA
WP_004193111.1\|1474583_1476410_-	translational GTPase TypA	NA	NA	NA	NA
WP_009930591.1\|1476406_1476562_-	hypothetical protein	NA	NA	NA	NA
WP_004192835.1\|1476702_1477200_+	MarR family transcriptional regulator	NA	NA	NA	NA
WP_004191557.1\|1477299_1478796_+	efflux transporter outer membrane subunit	NA	NA	NA	NA
WP_004192058.1\|1478863_1480099_+	HlyD family efflux transporter periplasmic adaptor subunit	NA	NA	NA	NA
WP_004193982.1\|1480121_1481681_+	DHA2 family efflux MFS transporter permease subunit	NA	NA	NA	NA
WP_011203915.1\|1481951_1482887_-\|tRNA	tRNA pseudouridine(55) synthase TruB	NA	NA	NA	NA
WP_004199441.1\|1482913_1483282_-	30S ribosome-binding factor RbfA	NA	NA	NA	NA
WP_004197388.1\|1483387_1486315_-	translation initiation factor IF-2	A0A2H4UTS4	Bodo_saltans_virus	5.2e-23	25.3
WP_004193517.1\|1486406_1487882_-	transcription termination/antitermination protein NusA	NA	NA	NA	NA
WP_004193908.1\|1487878_1488340_-	ribosome maturation factor RimP	NA	NA	NA	NA
WP_004191876.1\|1488644_1490309_-	pseudouridine synthase	NA	NA	NA	NA
WP_004192767.1\|1490372_1491701_-	SMC-Scp complex subunit ScpB	A0A1B1IVT7	uncultured_Mediterranean_phage	5.3e-23	35.1
WP_004193481.1\|1492119_1493022_-	LysR family transcriptional regulator	A0A2P0ZL89	Lactobacillus_phage	4.5e-10	23.6
WP_004550556.1\|1493215_1493413_-	hypothetical protein	NA	NA	NA	NA
WP_004199443.1\|1493440_1493842_+\|transposase	transposase	NA	NA	NA	NA
WP_009920735.1\|1493861_1493963_+	hypothetical protein	NA	NA	NA	NA
WP_004521676.1\|1494047_1494305_+	hypothetical protein	NA	NA	NA	NA
WP_004199444.1\|1494463_1494781_-	hypothetical protein	NA	NA	NA	NA
WP_004192638.1\|1494981_1495704_+	YdcF family protein	NA	NA	NA	NA
WP_004192834.1\|1495942_1496221_+	hypothetical protein	NA	NA	NA	NA
WP_004191628.1\|1496369_1496627_+	hypothetical protein	NA	NA	NA	NA
WP_004193694.1\|1496676_1496967_-	hypothetical protein	NA	NA	NA	NA
WP_038802950.1\|1497388_1498508_+\|transposase	IS3 family transposase	S5WIU1	Leptospira_phage	3.6e-49	39.5
WP_004197405.1\|1499307_1500534_-	outer membrane protein assembly factor BamC	NA	NA	NA	NA
WP_004205966.1\|1500862_1501354_+	DUF2844 domain-containing protein	NA	NA	NA	NA
WP_004192528.1\|1501364_1502567_+	DUF3443 domain-containing protein	NA	NA	NA	NA
WP_011203917.1\|1503013_1503220_-	hypothetical protein	NA	NA	NA	NA
WP_038802950.1\|1503354_1504475_-\|transposase	IS3 family transposase	S5WIU1	Leptospira_phage	3.6e-49	39.5

DBSCAN-SWA_6

2203125 : 2287423

Streptococcus_phage(33.33%)

transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_004191998.1\|2203125_2204589_+\|transposase	IS1182-like element ISBma2 family transposase	A0A1X9I5T2	Streptococcus_phage	8.8e-80	38.6
WP_004199567.1\|2204697_2205267_-	phasin family protein	NA	NA	NA	NA
WP_004557110.1\|2205936_2207058_+	D-alanyl-D-alanine endopeptidase	NA	NA	NA	NA
WP_004191998.1\|2207177_2208641_-\|transposase	IS1182-like element ISBma2 family transposase	A0A1X9I5T2	Streptococcus_phage	8.8e-80	38.6
WP_004192702.1\|2208897_2210667_-	dihydrolipoyl dehydrogenase	A0A2K5B2C5	Erysipelothrix_phage	6.8e-34	23.8
WP_004193075.1\|2210974_2212564_-	dihydrolipoyllysine-residue acetyltransferase	NA	NA	NA	NA
WP_004199569.1\|2212696_2215393_-	pyruvate dehydrogenase (acetyl-transferring), homodimeric type	NA	NA	NA	NA
WP_011204038.1\|2215536_2218176_+	PAS domain S-box protein	NA	NA	NA	NA
WP_004193928.1\|2218172_2218811_+	response regulator transcription factor	NA	NA	NA	NA
WP_004192825.1\|2219127_2219985_+	bifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase FolD	A0A249XZQ2	Enterococcus_phage	4.1e-37	39.9
WP_011204039.1\|2220238_2220562_+	hypothetical protein	NA	NA	NA	NA
WP_004191126.1\|2220678_2222778_+	M3 family metallopeptidase	A0A1V0SD92	Indivirus	1.7e-39	21.8
WP_009931175.1\|2223007_2224222_-	DNA polymerase IV	NA	NA	NA	NA
WP_004192547.1\|2224162_2224447_+	hypothetical protein	NA	NA	NA	NA
WP_004193983.1\|2224939_2226220_+	NarK/NasA family nitrate transporter	NA	NA	NA	NA
WP_004192248.1\|2226263_2227649_+	NarK family nitrate/nitrite MFS transporter	NA	NA	NA	NA
WP_004193149.1\|2227899_2231625_+	nitrate reductase subunit alpha	NA	NA	NA	NA
WP_004193619.1\|2231621_2233175_+	nitrate reductase subunit beta	A0A077SL61	Escherichia_phage	2.9e-20	46.5
WP_004192818.1\|2233171_2233876_+	nitrate reductase molybdenum cofactor assembly chaperone	NA	NA	NA	NA
WP_004191967.1\|2233912_2234599_+	respiratory nitrate reductase subunit gamma	NA	NA	NA	NA
WP_004193869.1\|2234740_2236663_+	HAMP domain-containing protein	NA	NA	NA	NA
WP_004192421.1\|2236698_2237400_+	response regulator	NA	NA	NA	NA
WP_011204042.1\|2237371_2237548_-	hypothetical protein	NA	NA	NA	NA
WP_004193531.1\|2237546_2238323_+	exodeoxyribonuclease III	NA	NA	NA	NA
WP_004191998.1\|2238605_2240069_-\|transposase	IS1182-like element ISBma2 family transposase	A0A1X9I5T2	Streptococcus_phage	8.8e-80	38.6
WP_004192209.1\|2240201_2241737_-	nitrogen regulation protein NR(I)	NA	NA	NA	NA
WP_004532137.1\|2241774_2242869_-	nitrogen regulation protein NR(II)	NA	NA	NA	NA
WP_004191998.1\|2243041_2244505_-\|transposase	IS1182-like element ISBma2 family transposase	A0A1X9I5T2	Streptococcus_phage	8.8e-80	38.6
WP_004192601.1\|2244676_2246092_-	type I glutamate--ammonia ligase	NA	NA	NA	NA
WP_004191860.1\|2246496_2246961_+	rhodanese-like domain-containing protein	NA	NA	NA	NA
WP_004192990.1\|2247213_2248032_-	competence/damage-inducible protein A	NA	NA	NA	NA
WP_004193555.1\|2248028_2248862_-	EI24 domain-containing protein	NA	NA	NA	NA
WP_009966722.1\|2248917_2249190_+	hypothetical protein	NA	NA	NA	NA
WP_004192998.1\|2249405_2250395_-	sterol desaturase family protein	NA	NA	NA	NA
WP_004192001.1\|2250411_2251404_-	beta-propeller fold lactonase family protein	A0A2H4JCI3	uncultured_Caudovirales_phage	3.5e-11	59.6
WP_004202033.1\|2251505_2255633_-	ATP-dependent RNA helicase HrpA	A0A1V0SBU4	Catovirus	4.3e-47	28.5
WP_004192168.1\|2255656_2257033_+	amino-acid N-acetyltransferase	NA	NA	NA	NA
WP_004193961.1\|2257085_2257361_+	oxidative damage protection protein	NA	NA	NA	NA
WP_076882745.1\|2257533_2258877_-	MHS family MFS transporter	NA	NA	NA	NA
WP_038796647.1\|2259073_2260609_-	CoA transferase	NA	NA	NA	NA
WP_004206369.1\|2260605_2262399_-	isovaleryl-CoA dehydrogenase	NA	NA	NA	NA
WP_004193679.1\|2262507_2263410_+	LysR family transcriptional regulator	NA	NA	NA	NA
WP_038802950.1\|2265247_2266368_-\|transposase	IS3 family transposase	S5WIU1	Leptospira_phage	3.6e-49	39.5
WP_004534273.1\|2266909_2268010_+	porin	NA	NA	NA	NA
WP_004193987.1\|2268478_2268817_-	P-II family nitrogen regulator	NA	NA	NA	NA
WP_004198600.1\|2268877_2270578_-	NAD+ synthase	A0A2L0UZF5	Agrobacterium_phage	5.8e-91	36.8
WP_004192390.1\|2270698_2271877_+	N-acetyltransferase	NA	NA	NA	NA
WP_011807750.1\|2272865_2273780_+	GIY-YIG nuclease family protein	W8W2G4	Invertebrate_iridovirus	2.1e-07	43.1
WP_004192356.1\|2273838_2274366_-	inorganic diphosphatase	A0A2H4J8U1	uncultured_Caudovirales_phage	9.0e-51	53.8
WP_004193515.1\|2274526_2275966_+	aldehyde dehydrogenase family protein	NA	NA	NA	NA
WP_004192728.1\|2276054_2276813_+	SDR family oxidoreductase	NA	NA	NA	NA
WP_004192161.1\|2276851_2278159_+	MFS transporter	NA	NA	NA	NA
WP_004193604.1\|2278339_2279530_-	heme biosynthesis protein HemY	NA	NA	NA	NA
WP_004193146.1\|2279534_2281514_-	fused uroporphyrinogen-III synthase HemD/membrane protein HemX	NA	NA	NA	NA
WP_004193185.1\|2281513_2282503_-	hydroxymethylbilane synthase	NA	NA	NA	NA
WP_004199404.1\|2282537_2282717_-	hypothetical protein	NA	NA	NA	NA
WP_004191560.1\|2282829_2285814_+	phosphoenolpyruvate carboxylase	NA	NA	NA	NA
WP_011203959.1\|2285959_2287423_+\|transposase	IS1182-like element ISBma2 family transposase	A0A1X9I5T2	Streptococcus_phage	2.6e-79	38.3

DBSCAN-SWA_7

2505806 : 2570042

Streptococcus_phage(27.78%)

protease,transposase,tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_004191998.1\|2505806_2507270_-\|transposase	IS1182-like element ISBma2 family transposase	A0A1X9I5T2	Streptococcus_phage	8.8e-80	38.6
WP_004189921.1\|2507380_2508352_-	thymidylate synthase	A0A1V0DY05	Yersinia_phage	2.9e-47	36.1
WP_004189039.1\|2508408_2509794_-	sigma-54-dependent Fis family transcriptional regulator	NA	NA	NA	NA
WP_004195958.1\|2509755_2510052_+	hypothetical protein	NA	NA	NA	NA
WP_004201791.1\|2510316_2510685_+	hypothetical protein	NA	NA	NA	NA
WP_011832229.1\|2510681_2511959_+	hypothetical protein	NA	NA	NA	NA
WP_080516914.1\|2512220_2514059_+	sigma-54-dependent Fis family transcriptional regulator	NA	NA	NA	NA
WP_004189313.1\|2514266_2514770_+	dihydrofolate reductase	A0A0A0PL85	Bacillus_phage	9.6e-26	40.4
WP_004191998.1\|2514898_2516362_-\|transposase	IS1182-like element ISBma2 family transposase	A0A1X9I5T2	Streptococcus_phage	8.8e-80	38.6
WP_004188997.1\|2516498_2517869_-\|protease	metalloprotease PmbA	NA	NA	NA	NA
WP_004195962.1\|2518014_2518623_+	ribosome-associated protein	NA	NA	NA	NA
WP_004189637.1\|2518603_2519224_+	molybdopterin adenylyltransferase	NA	NA	NA	NA
WP_004189767.1\|2519471_2520077_-	oligoribonuclease	Q8B5Y0	Diachasmimorpha_longicaudata_entomopoxvirus	4.2e-28	40.4
WP_004189931.1\|2520195_2521461_+	M48 family metallopeptidase	NA	NA	NA	NA
WP_004189924.1\|2521457_2522402_+	ribosome small subunit-dependent GTPase A	NA	NA	NA	NA
WP_004189573.1\|2522470_2522788_+	lipoprotein	NA	NA	NA	NA
WP_004195964.1\|2522954_2523893_-	CobD/CbiB family protein	NA	NA	NA	NA
WP_004550123.1\|2523993_2524677_-	CoA pyrophosphatase	NA	NA	NA	NA
WP_009931411.1\|2525313_2525604_+	hypothetical protein	NA	NA	NA	NA
WP_004190182.1\|2525600_2526191_+	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_004189360.1\|2526511_2526901_-	50S ribosomal protein L19	NA	NA	NA	NA
WP_004189914.1\|2527038_2527833_-\|tRNA	tRNA (guanosine(37)-N1)-methyltransferase TrmD	NA	NA	NA	NA
WP_004195969.1\|2527834_2528524_-	ribosome maturation factor RimM	NA	NA	NA	NA
WP_004189402.1\|2528568_2528823_-	30S ribosomal protein S16	NA	NA	NA	NA
WP_004189308.1\|2530263_2530731_+	TM2 domain-containing protein	NA	NA	NA	NA
WP_004189906.1\|2530765_2531923_-	PA0069 family radical SAM protein	NA	NA	NA	NA
WP_004188962.1\|2532031_2532520_-	winged helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_004189387.1\|2532667_2533954_+	D-amino acid dehydrogenase	NA	NA	NA	NA
WP_004189890.1\|2535969_2536905_-	electron transfer flavoprotein subunit alpha	NA	NA	NA	NA
WP_004189750.1\|2536920_2537670_-	electron transfer flavoprotein subunit beta/FixA family protein	NA	NA	NA	NA
WP_011807766.1\|2537896_2538691_-	MetQ/NlpA family ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_004189862.1\|2538764_2539418_-	ABC transporter permease	NA	NA	NA	NA
WP_004190044.1\|2539407_2540442_-	methionine ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	6.8e-34	39.1
WP_004190087.1\|2540750_2541593_+	alpha/beta hydrolase	A7XCB7	Tanapox_virus	7.2e-18	27.2
WP_004188957.1\|2541935_2542859_-	histone deacetylase family protein	A0A2K9KZC4	Tupanvirus	8.4e-44	36.5
WP_085962730.1\|2542986_2544333_+	lytic murein transglycosylase B	NA	NA	NA	NA
WP_004532363.1\|2544558_2545461_-	cysteine synthase CysM	A0A1X9I5F1	Streptococcus_phage	1.9e-53	39.9
WP_004204273.1\|2545472_2545772_-	hypothetical protein	NA	NA	NA	NA
WP_004189725.1\|2545784_2546102_-	competence protein ComE	NA	NA	NA	NA
WP_004190173.1\|2546173_2547166_-	ADP-glyceromanno-heptose 6-epimerase	R9S880	Prochlorococcus_phage	9.1e-28	30.9
WP_004200795.1\|2547224_2548211_-	D-glycero-beta-D-manno-heptose-7-phosphate kinase	A0A2H4N7X4	Lake_Baikal_phage	8.8e-15	26.5
WP_004189214.1\|2548179_2549580_-	UDP-glucose/GDP-mannose dehydrogenase family protein	A0A127AXI2	Bacillus_phage	2.1e-78	38.3
WP_004188993.1\|2549700_2550870_-	lipopolysaccharide assembly protein LapB	NA	NA	NA	NA
WP_011203815.1\|2550922_2551417_-	LapA family protein	NA	NA	NA	NA
WP_004191998.1\|2551451_2552915_-\|transposase	IS1182-like element ISBma2 family transposase	A0A1X9I5T2	Streptococcus_phage	8.8e-80	38.6
WP_004189865.1\|2553033_2553357_-	integration host factor subunit beta	A7KV42	Bacillus_phage	4.7e-10	38.9
WP_004189285.1\|2553379_2555092_-	30S ribosomal protein S1	NA	NA	NA	NA
WP_004189396.1\|2555236_2555923_-	(d)CMP kinase	NA	NA	NA	NA
WP_096325444.1\|2555943_2558166_-	3-phosphoshikimate 1-carboxyvinyltransferase	NA	NA	NA	NA
WP_011203817.1\|2558113_2558290_-	hypothetical protein	NA	NA	NA	NA
WP_004190098.1\|2558369_2559452_-	prephenate dehydratase	NA	NA	NA	NA
WP_004189993.1\|2559486_2560569_-	3-phosphoserine/phosphohydroxythreonine transaminase	M1Q1P2	Streptococcus_phage	8.5e-88	47.2
WP_004189806.1\|2560742_2561339_-	DUF2059 domain-containing protein	NA	NA	NA	NA
WP_004189243.1\|2561437_2564038_-	DNA gyrase subunit A	A0A172JHV7	Bacillus_phage	9.5e-101	29.8
WP_004189892.1\|2564548_2565223_+	OmpA family protein	NA	NA	NA	NA
WP_004532296.1\|2565391_2566090_+	bifunctional 3-demethylubiquinone 3-O-methyltransferase/2-octaprenyl-6-hydroxy phenol methylase	NA	NA	NA	NA
WP_004190123.1\|2566115_2566841_+	phosphoglycolate phosphatase	NA	NA	NA	NA
WP_038802950.1\|2567438_2568559_-\|transposase	IS3 family transposase	S5WIU1	Leptospira_phage	3.6e-49	39.5
WP_004186184.1\|2568821_2570042_+\|transposase	ISL3-like element ISBma1 family transposase	A9YX10	Burkholderia_phage	6.6e-238	99.0

DBSCAN-SWA_8

2603784 : 2641955

Leptospira_phage(30.0%)

tRNA,transposase,integrase

attL 2614152:2614211|attR 2616688:2617884

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_004186184.1\|2603784_2605005_+\|transposase	ISL3-like element ISBma1 family transposase	A9YX10	Burkholderia_phage	6.6e-238	99.0
WP_004190100.1\|2605346_2605607_+	hypothetical protein	NA	NA	NA	NA
WP_004197792.1\|2605629_2606106_+	hypothetical protein	NA	NA	NA	NA
WP_004550102.1\|2606274_2606523_+	hypothetical protein	NA	NA	NA	NA
WP_011205188.1\|2607180_2607528_+	GlsB/YeaQ/YmgE family stress response membrane protein	NA	NA	NA	NA
WP_004203540.1\|2607814_2608303_-	hypothetical protein	NA	NA	NA	NA
WP_004554214.1\|2608299_2609571_-	exo-alpha-sialidase	NA	NA	NA	NA
WP_004188913.1\|2609558_2611895_-	TonB-dependent receptor	NA	NA	NA	NA
WP_011203824.1\|2612041_2612518_-	DUF2946 domain-containing protein	NA	NA	NA	NA
WP_011203825.1\|2613043_2613637_+	chorismate mutase	NA	NA	NA	NA
WP_004557196.1\|2613633_2613846_-	hypothetical protein	NA	NA	NA	NA
2614152:2614211	attL	NA	NA	NA	NA
WP_038802950.1\|2614198_2615319_-\|transposase	IS3 family transposase	S5WIU1	Leptospira_phage	3.6e-49	39.5
WP_004189968.1\|2615349_2616021_-\|integrase	integrase arm-type DNA-binding domain-containing protein	B7SYF8	Stenotrophomonas_phage	1.3e-46	46.1
WP_011203829.1\|2616247_2616340_-	hypothetical protein	NA	NA	NA	NA
WP_038802950.1\|2616734_2617855_-\|transposase	IS3 family transposase	S5WIU1	Leptospira_phage	3.6e-49	39.5
WP_004550771.1\|2618137_2618659_-	hypothetical protein	NA	NA	NA	NA
2616688:2617884	attR	NA	NA	NA	NA
WP_004191998.1\|2618927_2620391_+\|transposase	IS1182-like element ISBma2 family transposase	A0A1X9I5T2	Streptococcus_phage	8.8e-80	38.6
WP_004186453.1\|2620513_2621494_-	4-hydroxy-3-methylbut-2-enyl diphosphate reductase	NA	NA	NA	NA
WP_004186190.1\|2621496_2621952_-	peptidylprolyl isomerase	NA	NA	NA	NA
WP_004185928.1\|2622090_2622927_+	JAB domain-containing protein	NA	NA	NA	NA
WP_004186391.1\|2623220_2623454_+	50S ribosomal protein L28	NA	NA	NA	NA
WP_004185395.1\|2623471_2623639_+	50S ribosomal protein L33	NA	NA	NA	NA
WP_004554550.1\|2623761_2625408_+	L-aspartate oxidase	NA	NA	NA	NA
WP_004197485.1\|2625379_2625598_-	hypothetical protein	NA	NA	NA	NA
WP_004185611.1\|2625599_2626484_-	carboxylating nicotinate-nucleotide diphosphorylase	NA	NA	NA	NA
WP_004185886.1\|2626480_2627617_-	quinolinate synthase NadA	NA	NA	NA	NA
WP_004186237.1\|2627785_2628982_-	aminotransferase	NA	NA	NA	NA
WP_004186398.1\|2629178_2630531_-	mechanosensitive ion channel	NA	NA	NA	NA
WP_004186079.1\|2630542_2631805_-	RsmB/NOP family class I SAM-dependent RNA methyltransferase	NA	NA	NA	NA
WP_004185746.1\|2631801_2632464_-	phosphoribosylglycinamide formyltransferase	E3SNR5	Prochlorococcus_phage	1.6e-25	40.0
WP_004535897.1\|2632588_2633581_+	bifunctional riboflavin kinase/FAD synthetase	NA	NA	NA	NA
WP_004185348.1\|2633692_2636530_+\|tRNA	isoleucine--tRNA ligase	A0A1V0SJ93	Klosneuvirus	1.6e-80	26.0
WP_004186086.1\|2636529_2637030_+	lipoprotein signal peptidase	NA	NA	NA	NA
WP_004186216.1\|2637091_2638303_+	bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase CoaBC	Q9HH70	Methanothermobacter_phage	3.0e-41	31.9
WP_004186718.1\|2638366_2638813_+	dUTP diphosphatase	Q2NP83	Xanthomonas_phage	7.9e-48	64.4
WP_004185819.1\|2638901_2639684_-	membrane protein	NA	NA	NA	NA
WP_004185697.1\|2639848_2640595_-	hypothetical protein	NA	NA	NA	NA
WP_038802950.1\|2640834_2641955_-\|transposase	IS3 family transposase	S5WIU1	Leptospira_phage	3.6e-49	39.5

DBSCAN-SWA_9

2763141 : 2820732

Vibrio_phage(17.65%)

protease,transposase,tRNA,portal

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_004191998.1\|2763141_2764605_-\|transposase	IS1182-like element ISBma2 family transposase	A0A1X9I5T2	Streptococcus_phage	8.8e-80	38.6
WP_004190029.1\|2764771_2765542_-	exodeoxyribonuclease III	R4TWA8	Phaeocystis_globosa_virus	3.4e-30	33.8
WP_004189747.1\|2765573_2766413_-	hypothetical protein	NA	NA	NA	NA
WP_004190092.1\|2766539_2768012_-\|tRNA	Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatB	NA	NA	NA	NA
WP_004189326.1\|2768014_2769505_-\|tRNA	Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatA	NA	NA	NA	NA
WP_004189769.1\|2769617_2769917_-\|tRNA	Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatC	NA	NA	NA	NA
WP_011807773.1\|2770282_2771326_+	rod shape-determining protein	NA	NA	NA	NA
WP_004189331.1\|2771445_2772519_+	rod shape-determining protein MreC	NA	NA	NA	NA
WP_004189260.1\|2772515_2773028_+	rod shape-determining protein MreD	NA	NA	NA	NA
WP_004189575.1\|2773211_2775620_+	penicillin-binding protein 2	NA	NA	NA	NA
WP_004189171.1\|2775631_2776780_+	rod shape-determining protein RodA	NA	NA	NA	NA
WP_004190168.1\|2777158_2777935_-	sel1 repeat family protein	NA	NA	NA	NA
WP_004189570.1\|2777931_2778717_-	2-dehydro-3-deoxyglucarate aldolase	NA	NA	NA	NA
WP_009962395.1\|2778709_2779042_+	hypothetical protein	NA	NA	NA	NA
WP_004189793.1\|2779138_2779591_-	6-carboxytetrahydropterin synthase QueD	A0A088FAL2	Vibrio_phage	7.6e-14	30.8
WP_004189241.1\|2779610_2780243_-	7-carboxy-7-deazaguanine synthase	R4TAH8	Halovirus	2.1e-06	30.9
WP_004190026.1\|2780336_2781071_-	7-cyano-7-deazaguanine synthase QueC	A0A1B0Z0B4	Vibrio_phage	1.6e-50	42.5
WP_009918037.1\|2781067_2781358_-	hypothetical protein	NA	NA	NA	NA
WP_004189647.1\|2781538_2782222_-	response regulator	NA	NA	NA	NA
WP_004189034.1\|2782222_2784631_-	PAS domain-containing sensor histidine kinase	NA	NA	NA	NA
WP_004188929.1\|2784632_2785223_-	DUF4390 domain-containing protein	NA	NA	NA	NA
WP_004189046.1\|2785219_2786629_-	16S rRNA (cytosine(967)-C(5))-methyltransferase RsmB	NA	NA	NA	NA
WP_004189409.1\|2787006_2787864_-\|protease	zinc metalloprotease HtpX	NA	NA	NA	NA
WP_004189288.1\|2787973_2788609_-	LysE family translocator	NA	NA	NA	NA
WP_004200737.1\|2788729_2789713_-\|tRNA	methionyl-tRNA formyltransferase	E3SNR5	Prochlorococcus_phage	1.3e-07	38.0
WP_004201745.1\|2789744_2790248_-	peptide deformylase	A0A067XQZ3	Caulobacter_phage	2.7e-12	34.3
WP_004190020.1\|2790476_2791667_+	DNA-protecting protein DprA	S6BFL3	Thermus_phage	2.0e-21	39.2
WP_004190199.1\|2791726_2792098_+	thioredoxin family protein	NA	NA	NA	NA
WP_004200734.1\|2792308_2794918_+	DNA topoisomerase III	A0A2P1ELA0	Moumouvirus	7.7e-18	25.7
WP_004189230.1\|2795139_2796195_-	LysR family transcriptional regulator	NA	NA	NA	NA
WP_004188904.1\|2796644_2797661_+	D-2-hydroxyacid dehydrogenase family protein	NA	NA	NA	NA
WP_004189208.1\|2797781_2798651_-	patatin-like phospholipase family protein	NA	NA	NA	NA
WP_004200732.1\|2798688_2799093_-	PaaI family thioesterase	NA	NA	NA	NA
WP_004203542.1\|2799483_2800704_+\|transposase	ISL3-like element ISBma1 family transposase	A9YX10	Burkholderia_phage	3.9e-238	99.3
WP_009918009.1\|2801166_2801421_+	hypothetical protein	NA	NA	NA	NA
WP_038802950.1\|2802020_2803140_+\|transposase	IS3 family transposase	S5WIU1	Leptospira_phage	3.6e-49	39.5
WP_004200731.1\|2803192_2803675_+	DUF2778 domain-containing protein	NA	NA	NA	NA
WP_004188977.1\|2803671_2803956_+	hypothetical protein	NA	NA	NA	NA
WP_004188948.1\|2804028_2805042_-\|portal	phage portal protein	A4JWQ2	Burkholderia_virus	1.3e-194	99.4
WP_011203781.1\|2805694_2805859_-	hypothetical protein	NA	NA	NA	NA
WP_004189258.1\|2806065_2806941_-	N-carbamoylputrescine amidase	A7IVZ1	Paramecium_bursaria_Chlorella_virus	9.6e-74	47.3
WP_004190014.1\|2806951_2808064_-	histone deacetylase	A0A2K9KZC4	Tupanvirus	3.2e-37	30.8
WP_004201742.1\|2808092_2809187_-	polyamine ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_004189434.1\|2809329_2810298_+	LysR family transcriptional regulator	NA	NA	NA	NA
WP_004189874.1\|2810400_2810970_+	periplasmic heavy metal sensor	NA	NA	NA	NA
WP_004189689.1\|2811562_2812111_+	hypothetical protein	NA	NA	NA	NA
WP_011203779.1\|2812126_2812378_+	hypothetical protein	NA	NA	NA	NA
WP_004189592.1\|2812374_2813823_+	RNA polymerase sigma factor RpoD/SigA	A0A2I7SAT0	Vibrio_phage	4.9e-30	33.5
WP_004204797.1\|2813841_2815443_-	glutamate--cysteine ligase	NA	NA	NA	NA
WP_004200726.1\|2815614_2816556_-	DNA-3-methyladenine glycosylase 2 family protein	NA	NA	NA	NA
WP_004190110.1\|2816552_2817647_-	bifunctional DNA-binding transcriptional regulator/O6-methylguanine-DNA methyltransferase Ada	A0A0G2Y1B6	Acanthamoeba_polyphaga_mimivirus	3.8e-19	37.4
WP_004197761.1\|2818048_2818465_+	lactoylglutathione lyase	NA	NA	NA	NA
WP_004197759.1\|2818680_2819235_-	YaeQ family protein	NA	NA	NA	NA
WP_038802950.1\|2819612_2820732_+\|transposase	IS3 family transposase	S5WIU1	Leptospira_phage	3.6e-49	39.5

DBSCAN-SWA_10

3220190 : 3284976

Burkholderia_phage(13.33%)

terminase,protease,transposase,integrase

attL 3226444:3226462|attR 3285801:3285819

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_004539219.1\|3220190_3220718_+\|protease	ClpXP protease specificity-enhancing factor	A0A1S5R3H3	Pseudomonas_phage	2.0e-21	51.0
WP_004199888.1\|3220939_3221437_+\|terminase	terminase	K4NXI4	Burkholderia_phage	2.6e-55	100.0
WP_038802950.1\|3221798_3222918_+\|transposase	IS3 family transposase	S5WIU1	Leptospira_phage	3.6e-49	39.5
WP_004199882.1\|3223543_3223816_+	flagellar biosynthesis protein FliQ	NA	NA	NA	NA
WP_004201278.1\|3223934_3224717_+	flagellar biosynthetic protein FliR	NA	NA	NA	NA
WP_004199881.1\|3225036_3225465_-	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_004199880.1\|3225546_3226422_+	class I SAM-dependent methyltransferase	NA	NA	NA	NA
WP_004199879.1\|3226414_3226936_+	DUF2938 domain-containing protein	NA	NA	NA	NA
3226444:3226462	attL	NA	NA	NA	NA
WP_004199878.1\|3227093_3228107_+	transporter substrate-binding domain-containing protein	NA	NA	NA	NA
WP_004199877.1\|3228190_3228988_+	ABC transporter ATP-binding protein	G3M9Y6	Bacillus_virus	3.5e-30	35.3
WP_004199876.1\|3229006_3229864_+	ABC transporter permease	NA	NA	NA	NA
WP_004197153.1\|3229941_3231321_+	sensor histidine kinase	NA	NA	NA	NA
WP_004197150.1\|3231331_3232009_+	response regulator	NA	NA	NA	NA
WP_004549852.1\|3232331_3233459_+	porin	NA	NA	NA	NA
WP_004197141.1\|3233494_3233677_+	hypothetical protein	NA	NA	NA	NA
WP_004266287.1\|3233913_3235947_+	site-specific DNA-methyltransferase	A0A2K5B2C1	Erysipelothrix_phage	3.3e-85	33.5
WP_004197137.1\|3235987_3239017_+	type III restriction endonuclease subunit R	A0A2K5B256	Erysipelothrix_phage	2.2e-181	38.7
WP_011204147.1\|3239100_3239403_+	hypothetical protein	NA	NA	NA	NA
WP_004197133.1\|3239554_3240655_+	porin	NA	NA	NA	NA
WP_004199873.1\|3241054_3242014_+	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_004538585.1\|3242136_3242868_-	ATP-binding cassette domain-containing protein	W8CYL7	Bacillus_phage	1.6e-05	25.3
WP_004197129.1\|3243240_3243963_-	ATP-binding cassette domain-containing protein	A0A2H4PQG7	Staphylococcus_phage	3.8e-07	25.5
WP_004205008.1\|3243959_3245009_-	branched-chain amino acid ABC transporter permease	NA	NA	NA	NA
WP_004197127.1\|3245005_3245884_-	branched-chain amino acid ABC transporter permease	NA	NA	NA	NA
WP_004197126.1\|3245888_3247148_-	ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_011204146.1\|3247275_3247368_-	hypothetical protein	NA	NA	NA	NA
WP_004198383.1\|3247364_3248870_-	aldehyde dehydrogenase family protein	NA	NA	NA	NA
WP_004198382.1\|3248925_3249318_-	nuclear transport factor 2 family protein	NA	NA	NA	NA
WP_004198380.1\|3249328_3250138_-	hypothetical protein	NA	NA	NA	NA
WP_004198379.1\|3250183_3250981_-	SDR family oxidoreductase	A0A2N9QUX2	Trichoplusia_ni_ascovirus	3.3e-12	28.8
WP_004198377.1\|3251065_3252715_-	GMC family oxidoreductase	A0A1V0SI18	Klosneuvirus	2.0e-56	30.9
WP_004198376.1\|3253442_3253784_+	PadR family transcriptional regulator	NA	NA	NA	NA
WP_004198375.1\|3253780_3254917_+	DUF1700 domain-containing protein	NA	NA	NA	NA
WP_004199869.1\|3254996_3255116_+	hypothetical protein	NA	NA	NA	NA
WP_038802950.1\|3255196_3256317_-\|transposase	IS3 family transposase	S5WIU1	Leptospira_phage	3.6e-49	39.5
WP_004200089.1\|3256407_3257517_+\|integrase	site-specific integrase	A0A1S5NNJ1	Burkholderia_phage	6.5e-168	79.9
WP_004202928.1\|3257934_3258834_+	cytochrome c	NA	NA	NA	NA
WP_004195888.1\|3259154_3261257_-	AAA family ATPase	A7KV33	Bacillus_phage	1.1e-94	34.8
WP_073699136.1\|3261506_3262349_+	hypothetical protein	NA	NA	NA	NA
WP_080516922.1\|3262345_3263149_+	SGNH/GDSL hydrolase family protein	NA	NA	NA	NA
WP_004545329.1\|3263231_3263519_+	hypothetical protein	NA	NA	NA	NA
WP_004185221.1\|3263662_3264715_+	oxidoreductase	NA	NA	NA	NA
WP_004195883.1\|3264886_3265246_+	lipoprotein	NA	NA	NA	NA
WP_004202927.1\|3266017_3267136_+	glycine cleavage system aminomethyltransferase GcvT	NA	NA	NA	NA
WP_004195879.1\|3267229_3267610_+	glycine cleavage system protein GcvH	NA	NA	NA	NA
WP_004195877.1\|3267914_3270842_+	aminomethyl-transferring glycine dehydrogenase	M4QFZ1	Prochlorococcus_phage	2.8e-258	51.2
WP_004185207.1\|3270832_3270958_-	hypothetical protein	NA	NA	NA	NA
WP_004195875.1\|3270993_3272112_+	alginate lyase family protein	NA	NA	NA	NA
WP_004195873.1\|3272145_3273534_+	L-serine ammonia-lyase	NA	NA	NA	NA
WP_011205306.1\|3273568_3274750_-	hypothetical protein	NA	NA	NA	NA
WP_004195870.1\|3274977_3276681_+	thiamine pyrophosphate-binding protein	NA	NA	NA	NA
WP_004185233.1\|3276709_3277777_+	hypothetical protein	NA	NA	NA	NA
WP_004195868.1\|3277895_3278924_-	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_004195866.1\|3278967_3279147_-	hypothetical protein	NA	NA	NA	NA
WP_004556617.1\|3279219_3280740_+	aldehyde dehydrogenase family protein	NA	NA	NA	NA
WP_004195862.1\|3281006_3281252_-	hypothetical protein	NA	NA	NA	NA
WP_004195860.1\|3281317_3282121_-	ethanolamine ammonia-lyase subunit EutC	NA	NA	NA	NA
WP_004195859.1\|3282117_3283458_-	ethanolamine ammonia-lyase subunit EutB	NA	NA	NA	NA
WP_004191998.1\|3283512_3284976_-\|transposase	IS1182-like element ISBma2 family transposase	A0A1X9I5T2	Streptococcus_phage	8.8e-80	38.6
3285801:3285819	attR	NA	NA	NA	NA

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

2. NC_008784

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Crispr_ID: NC_008784_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_008784_1

20888-21050

Orphan

Consensus_repeat	Method
GGCGGGCCGGCCGCCG---------------------------CGCGGGCG	PILER-CR

2 spacers

The CRISPR arrays of NC_008784_1

>merge|NC_008784|1|20888-21050|PILER-CR
GGCCGCTCGGCCGCCGCGCGGGCGCGTGTTCCACGTGGCGGCCTGCGCCGTGTCGGCCGCGGCGGCCGTGCGGAGCGGGCCGGCCGCCGCGGCGATGGTGGCCGCGCGGATCACGTGGATCACGTTGACGGCGTTGAACGGCGGGCCGGCCGCCGCGCGGGCG

>NC_008784|1|1|20888-21050|PILER-CR
GGCCGCTCGGCCGCCGCGCGGGCG	CGTGTTCCACGTGGCGGCCTGCGCCGTGTCGGCCGCGGCGGCCGTGCGG
AGCGGGCCGGCCGCCGCGGCGATG	GTGGCCGCGCGGATCACGTGGATCACGTTGACGGCGTTGAACGGCGGG
CCGGCCGCCGCGCGGGCG

Protein	Signature genes	Signature genes Name	Protein_function
NC_008784.1\|WP_004524134.1\|17132_17273_-\|bacteriophage-protein	unknown	unknown	unknown
NC_008784.1\|WP_004184790.1\|19511_20867_+\|amino-acid-permease	unknown	unknown	gnl\|CDD\|163522
NC_008784.1\|WP_011204479.1\|24529_25162_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|237057
NC_008784.1\|WP_004197879.1\|17943_18432_-\|membrane-protein	unknown	unknown	gnl\|CDD\|377190
NC_008784.1\|WP_004266238.1\|32322_33861_+\|efflux-transporter-outer-membrane-subunit	unknown	unknown	gnl\|CDD\|182103
NC_008784.1\|WP_133307164.1\|14829_16188_-\|TolC-family-protein	unknown	unknown	gnl\|CDD\|224455
NC_008784.1\|WP_004197874.1\|16248_16434_-\|hypothetical-protein	unknown	unknown	unknown
NC_008784.1\|WP_004197880.1\|18758_19244_+\|YbaK/EbsC-family-protein	unknown	unknown	gnl\|CDD\|239824
NC_008784.1\|WP_004199160.1\|29086_32188_+\|MMPL-family-transporter	unknown	unknown	gnl\|CDD\|169983
NC_008784.1\|WP_004199606.1\|21913_23914_-\|ATP-dependent-zinc-metalloprotease-FtsH	unknown	unknown	gnl\|CDD\|273520
NC_008784.1\|WP_004205924.1\|17725_17956_+\|hypothetical-protein	unknown	unknown	unknown
NC_008784.1\|WP_004197875.1\|16450_16735_-\|hypothetical-protein	unknown	unknown	unknown
NC_008784.1\|WP_004539149.1\|34190_34835_+\|GTP-cyclohydrolase-II	unknown	unknown	gnl\|CDD\|234745
NC_008784.1\|WP_004197872.1\|13349_14819_-\|efflux-RND-transporter-periplasmic-adaptor-subunit	unknown	unknown	gnl\|CDD\|273386
NC_008784.1\|WP_004197695.1\|34831_36529_+\|WD40-repeat-domain-containing-protein	unknown	unknown	gnl\|CDD\|238121
NC_008784.1\|WP_073699266.1\|33857_34172_+\|hypothetical-protein	unknown	unknown	unknown
NC_008784.1\|WP_004202583.1\|10070_13304_-\|CusA/CzcA-family-heavy-metal-efflux-RND-transporter	unknown	unknown	gnl\|CDD\|129992
NC_008784.1\|WP_004199157.1\|27170_27842_-\|transcriptional-regulator	unknown	unknown	gnl\|CDD\|225222
NC_008784.1\|WP_004184876.1\|27992_29090_+\|efflux-RND-transporter-periplasmic-adaptor-subunit	unknown	unknown	gnl\|CDD\|273776
NC_008784.1\|WP_004197883.1\|21166_21775_+\|rhomboid-family-intramembrane-serine-protease	unknown	unknown	gnl\|CDD\|223777

Protein	Function_ID	Function_description	E-value
NC_008784.1\|WP_004184790.1\|19511_20867_+\|amino-acid-permease	gnl\|CDD\|163522	TIGR03810, arginine-ornithine_antiporter, arginine-ornithine antiporter. Members of this protein family are the arginine/ornithine antiporter, ArcD. This exchanger of ornithine for arginine occurs in a system with arginine deiminase, ornithine carbamoyltransferase, and carbamate kinase, with together turn arginine to ornithine with the generation of ATP and release of CO2. [Transport and binding proteins, Amino acids, peptides and amines].	4.43391e-175
NC_008784.1\|WP_011204479.1\|24529_25162_+\|hypothetical-protein	gnl\|CDD\|237057	PRK12323, PRK12323, DNA polymerase III subunit gamma/tau.	0.00628281
NC_008784.1\|WP_004197883.1\|21166_21775_+\|rhomboid-family-intramembrane-serine-protease	gnl\|CDD\|223777	COG0705, COG0705, Membrane associated serine protease [Amino acid transport and metabolism].	8.96274e-30
NC_008784.1\|WP_004266238.1\|32322_33861_+\|efflux-transporter-outer-membrane-subunit	gnl\|CDD\|182103	PRK09837, PRK09837, Cu(I)/Ag(I) efflux RND transporter outer membrane protein.	5.59568e-111
NC_008784.1\|WP_133307164.1\|14829_16188_-\|TolC-family-protein	gnl\|CDD\|224455	COG1538, TolC, Outer membrane protein [Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion].	3.39198e-32
NC_008784.1\|WP_004197880.1\|18758_19244_+\|YbaK/EbsC-family-protein	gnl\|CDD\|239824	cd04332, YbaK_like, YbaK-like. The YbaK family of deacylase domains includes the INS amino acid-editing domain of the bacterial class II prolyl tRNA synthetase (ProRS), and it's trans-acting homologs, YbaK, ProX, and PrdX. The primary function of INS is to hydrolyze mischarged cysteinyl-tRNA(Pro)'s, thus helping ensure the fidelity of translation. Organisms whose ProRS lacks the INS domain express an INS homolog in trans (e.g. YbaK, ProX, or PrdX).	4.00352e-32
NC_008784.1\|WP_004199160.1\|29086_32188_+\|MMPL-family-transporter	gnl\|CDD\|169983	PRK09579, PRK09579, multidrug efflux RND transporter permease subunit.	0
NC_008784.1\|WP_004199606.1\|21913_23914_-\|ATP-dependent-zinc-metalloprotease-FtsH	gnl\|CDD\|273520	TIGR01241, ATP-dependent_zinc_metalloprotease_FtsH, ATP-dependent metalloprotease FtsH. HflB(FtsH) is a pleiotropic protein required for correct cell division in bacteria. It has ATP-dependent zinc metalloprotease activity. It was formerly designated cell division protein FtsH. [Cellular processes, Cell division, Protein fate, Degradation of proteins, peptides, and glycopeptides].	0
NC_008784.1\|WP_004539149.1\|34190_34835_+\|GTP-cyclohydrolase-II	gnl\|CDD\|234745	PRK00393, ribA, GTP cyclohydrolase II RibA.	5.80202e-109
NC_008784.1\|WP_004197872.1\|13349_14819_-\|efflux-RND-transporter-periplasmic-adaptor-subunit	gnl\|CDD\|273386	TIGR00999, Nickel-cobalt-cadmium_resistance_protein_NccB, Membrane Fusion Protein cluster 2 (function with RND porters). [Transport and binding proteins, Other].	4.97736e-65
NC_008784.1\|WP_004197695.1\|34831_36529_+\|WD40-repeat-domain-containing-protein	gnl\|CDD\|238121	cd00200, WD40, WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from its N-terminus and the WD dipeptide at its C-terminus and is 40 residues long, hence the name WD40; between GH and WD lies a conserved core; serves as a stable propeller-like platform to which proteins can bind either stably or reversibly; forms a propeller-like structure with several blades where each blade is composed of a four-stranded anti-parallel b-sheet; instances with few detectable copies are hypothesized to form larger structures by dimerization; each WD40 sequence repeat forms the first three strands of one blade and the last strand in the next blade; the last C-terminal WD40 repeat completes the blade structure of the first WD40 repeat to create the closed ring propeller-structure; residues on the top and bottom surface of the propeller are proposed to coordinate interactions with other proteins and/or small ligands; 7 copies of the repeat are present in this alignment.	3.31012e-39
NC_008784.1\|WP_004202583.1\|10070_13304_-\|CusA/CzcA-family-heavy-metal-efflux-RND-transporter	gnl\|CDD\|129992	TIGR00914, Nickel-cobalt-cadmium_resistance_protein_NccA, heavy metal efflux pump, CzcA family. This model represents a family of H+/heavy metal cation antiporters. This family is one of several subfamilies within the scope of pfam00873. [Cellular processes, Detoxification, Transport and binding proteins, Cations and iron carrying compounds].	0
NC_008784.1\|WP_004199157.1\|27170_27842_-\|transcriptional-regulator	gnl\|CDD\|225222	COG2345, COG2345, Predicted transcriptional regulator [Transcription].	5.95232e-60
NC_008784.1\|WP_004184876.1\|27992_29090_+\|efflux-RND-transporter-periplasmic-adaptor-subunit	gnl\|CDD\|273776	TIGR01730, COG0845:_Membrane-fusion_protein, RND family efflux transporter, MFP subunit. This model represents the MFP (membrane fusion protein) component of the RND family of transporters. RND refers to Resistance, Nodulation, and cell Division. It is, in part, a subfamily of pfam00529 (Pfam release 7.5) but hits substantial numbers of proteins missed by that model. The related HlyD secretion protein, for which pfam00529 is named, is outside the scope of this model. Attributed functions imply outward transport. These functions include nodulation, acriflavin resistance, heavy metal efflux, and multidrug resistance proteins. Most members of this family are found in Gram-negative bacteria. The proposed function of MFP proteins is to bring the inner and outer membranes together and enable transport to the outside of the outer membrane. Note, however, that a few members of this family are found in Gram-positive bacteria, where there is no outer membrane. [Transport and binding proteins, Unknown substrate].	9.65507e-71
NC_008784.1\|WP_004197879.1\|17943_18432_-\|membrane-protein	gnl\|CDD\|377190	pfam04008, Adenosine_kin, Adenosine specific kinase. The structure of a member of this family from the hyperthermophilic archaeon Pyrobaculum aerophilum contains a modified histidine residue which is interpreted as stable phosphorylation. In vitro binding studies confirmed that adenosine and AMP but not ADP or ATP bind to the protein.	3.29857e-108

>NC_008784.1|WP_004184790.1|19511_20867_+|amino-acid-permease
MKHSVRHPFHPSTPLPASASAPLRAAAPRQLPFALLTALVIGSMIGSGIFSLPQNMASGAGAGAIVIGWAITGVGMLMLALVYQTLAHRKPELDNGVYAYAHASAGDFVGFNSAWGYWVSAWIGNVGYLVIVFGTLGYAFPAFGDGNTRAALAFQPHRFTTDFWGNVHLPGVLDQVKSTMLITVWVFIGIEGASVYSARAKNRDDVGRATIVGFVVVLLLLMAVSLLSLGIVSQPELAAMKNPSMAGVLEKAIGRTGVAIAGVGLLVSVGGALLAWTLLAAEAMFTPAKDGVMPAFLSRENAHGVPANALWATNGLVQLFLLVTLVSNATYQALISLATSMILVPYLFSAVYALVIAIKGEGYAPGEAVRVRDATIGAVATVYCGWLLYAAGPKYLLLSALLYAPGALLYAWAKRERGERPFKPFEAAILIALVAFASLAGWLVAAGRISL
>NC_008784.1|WP_004197880.1|18758_19244_+|YbaK/EbsC-family-protein
MSMSVTLQECLRQKASRYEVIHHPYSHSNMEAAAAAHVPGDRLAKTVLLEDAQGYVAAVLPTTHAVRLSELWAKTGRHLVLAKEVELRELFKDCDVGALPPVCMAYGMQTFLDDSLARQPDVYFEAGDHEELVHMDRDEFLALMDKAERASFSHKIQGVVS
>NC_008784.1|WP_004197879.1|17943_18432_-|membrane-protein
MLQLLSVAIDKPDTANFILGQTHFIKSVEDIHEALVGAVPGIRFGLAFCEASGKRLVRHSGTGAALTELACRNALAIGAGHCFLVFLGDGFYPLNVLNAIKAVPEVCRIFCATANPTEVVVAQSDQGRSILGVVDGFSPLGIETDEDVRWRKDLLRNIGYKA
>NC_008784.1|WP_004205924.1|17725_17956_+|hypothetical-protein
MQAVRSPLSRYRGWHGRASAMRTGPGLHGEAATDDRQSITGNPQSTHRTQARKRARFGQSPRDPAQDAATRGGYAL
>NC_008784.1|WP_004524134.1|17132_17273_-|bacteriophage-protein
MSLAAQDLIELLRLAQGGAGALTLHLLREIAGNLIAFGVADCRGGC
>NC_008784.1|WP_004197875.1|16450_16735_-|hypothetical-protein
MKRATSLAFAALFALAASSAFAHGMPERVFKERKPIRADARQEPSQRDASSAGCASGCPAGAALSRQDDRASGASPSSVGVEAAAGVHPAVNGG
>NC_008784.1|WP_004197874.1|16248_16434_-|hypothetical-protein
MRRGGALMRGRRTLDAPRPPAPPAPFLAPPHARASPRRIQPAAANVTKMSCSPHVCIAARP
>NC_008784.1|WP_133307164.1|14829_16188_-|TolC-family-protein
MSAAIAASAVQAQAQPAPAPSAPDGPAAAPPDARAASVSVTPAVSPAPISTSTVSVAPPALSLDDALALAAANNPLLKSARSSADASVGALVQAGARPNPTVSFLQEGFGRQERTTTAVVSQPIELGGKRRSRVDAASYGRESALASLDGRAAALRADVTGAFYGVLAAQRQLQVADESAAIAARSADMADKRARAGKVSPVEATKARVAQTAAQIELSNAQTRVAAALARLANATGSADVRGRAASGDLDALPAAEPLPQLLGRLDDAPLARAAKADMLRTNAQIAIERAKRVPDITVSAGVKHVVTGGAPDNQAVVGISIPLPLFDTNRGALLEAVHNAAKASADFDAERARLRLDLTQAYANYERATGEARRLKADVLPAARQSLDAMSRGYQLGKFGFLDVLDAQRTLFDAQSRYVQALADAHQSYADIERVVGAPARDASRPLAQLR
>NC_008784.1|WP_004197872.1|13349_14819_-|efflux-RND-transporter-periplasmic-adaptor-subunit
MQRKPLILAGAAAAGALAIVLALARAPSTSSAPAASGAAAAAPASGATGPHGGAMFAQGALSAEIVLSEKPDDARLVVYPFVDGKPVEQGAAVSATLTRHDGERVALQFAQAGAKYTSAQPIARPHVFDASIDVRIGARSASFPFSRADGAIALDDAQLGAARIGIARAGPAQIITSFQLPGEIKFNEDRTAHVVPRVAGIVERVAVSIGENVKPGQVLAVIASTDLADRRSELMTAERRLQAARTSYAREKTLWEERISAEQDYLQAQVQLREAEIAAANARQKLAALNASAASGALNRYELRAPFAGTIVEKHIAPGEAIAADANVFVVSDLSSVWAEMAVPAQRLNDVRVGRHATVSAAAFESKSSGPIAYVGALLGEQTRTAPARVVLPNPDGAWRPGMFVNVTVDAGAQNVPVAVESDALQDVDGAPAVFVRTPKGFVAQAIETGRRDERRVEIVKGLAPGQTYAAANSFVLKAELGKGVADEH
>NC_008784.1|WP_004202583.1|10070_13304_-|CusA/CzcA-family-heavy-metal-efflux-RND-transporter
MFERLIRFAIAHRWLVMLAIVAAASLGVYSYQKLPIDAVPDITNVQVQVNTSAPGYSPLEAEQRITYPVETAMAGLPNLEQTRSISRYGLSQVTVIFKDGTDIYFARQLVNERIQEAKDKLPPGIAPAMGPTSTGLGEIYLWTVEADAGARKPDGTRYTSADLRELQDWVVRPQLRNVPGVTEVNSIGGYVKEYRVAPNPTKLMSYGLTLADVVRALERNNDNVGAGYIEKRGEQYLVRVPGQARSAEDIANIVLVNAGGVPVRMKDIGAVDLGRELRTGAATANGEEVVLGTVFMLMGENSRTVAKAVAARMADVNRTLPAGVRAIAVYDRTVLVEKAVRTVKKNLLEGAVLVIAVLFLFLGNIRAAVITALVIPLSMLMTFTGMVNAKVSANLMSLGALDFGIIVDGAVVIVENCIRRLAHAQQAAGRPLTRDERFAEVFAASQEARRALIFGQLIIMVVYLPIFALTGVEGKMFHPMAITVVMALAAAMALTVTFIPAAVALFIGRRVEEKENRLMSAAKRLYAPVLDAFVARPGQVLAGATAVVALSLVLATRLGSEFIPSLNEGDLAVSAQRIPGTSLTQSVAMQQSIEKTLKARFPEIDRVFARTGTAEIAADPMPPNLSDGYIMLKPADQWPDPRKSRDALRGEIEAVLAQLPGNAYEFSQPIQLRFNELISGVRSDVAVKIFGDDMATLNATGEQIAAALQKVPGASEVKVEQTTGLPVLTVNLDRDKLARYGVTVGDVQDTVAAAVGGRKAGLLFQGDRRFDIVVRLPDELRTDVEAIKRLPIALPLAAPAGASGPLAQAPYVPLAELATVDTSPGPNQISREDGKRRVVVSANVRGRDVGSFVADARERIASDVRVPAGYWLSWGGQFEQLQSASERLKIVVPLALAMVFVLLFVMFNNAKDGLLVFTGIPFALTGDVVSLWLRGIPLSITAAVGFIALSGVAVLNGLVMISFIRNLRDEGAPLDAAVREGALTRLRPVLMTALVASLGFLPMAFATGTGAEVQRPLATVVIGGILSSTALTLLVLPVLYRVAHAAPPRATLGARAAGWLARLAPAAVLRRRRESSR
>NC_008784.1|WP_004197883.1|21166_21775_+|rhomboid-family-intramembrane-serine-protease
MTLAIVVLNVIGFLVELAAPERVLSLFALWPPRAGAGLPPAAAPAFHVWQLVTYSALHAGLSHLLFNMLGLVMFGRDVERALGRARFGTLYLASVVCGALTQLALARYSAAAAAPTIGASAGVFGVLAAYALLYPSRRVVLLIPPIPMRAWVFALLYAGGELLLGVAGAASGIAHFAHLGGMFGAIALMLAWGRPRSEWPVQ
>NC_008784.1|WP_004199606.1|21913_23914_-|ATP-dependent-zinc-metalloprotease-FtsH
MKSETGYMGFVVVLVFMVLLALQLATLSAPATQIAYSDFRKLAAAAQLDDLEVSPTRITGVLRSASAAAALPASDAEAIKRAGTPWRFSTKRVTDERLIDTLAATGTRYRGADDDTWIGTLASWIVPIAVFALVWNLMLRRPRGGLQDWSGVGKSKPRVYVEAKTGIDFDDIAGIDEAKAELQQIVAFLRAPARYQRLGGKIPKGVLIVGAPGTGKTLLAKAVAGEAGVPFFSTSGSSFVEMFVGVGAARVRDLFEQAQQKAPCIIFIDELDALGKVRGAGLASGNDEREQTLNQLLVEMDGFQANSGVILMAATNRPEILDPALLRPGRFDRHIAIDRPDLTGRRQILSVHVKHVKLGPDVDLGELASHTPGFVGADLANIVNEAALHAAELDKPAIDMSDFDEAIDRAMTGMERKSRVMSEREKITIAHHEAGHALIAQTRAHSDPVKKVSIIPRGIAALGYTQQVPTEDRYVLRKSELLDRLDVLLGGRVAEEIVFGDVSTGAENDLERATEMARHMVARYGMSERIGLATFGDADTQGLSPLVWQRGGERCSESTATRIDDEIQRLLAEAHDRVSRTLKERRGALERIAGYLLEHEVVDHDKLVRLVNDEPTPEPGARDPGGDAAKRSGIGAAPAKPPAEVGSAELRDPARKADNADHSVPQ
>NC_008784.1|WP_011204479.1|24529_25162_+|hypothetical-protein
MRGRRRNRGIAGMRSMAVRGATYTTEHRRSPARAIDADQRSATSRRFARADWCGFVANRSEPARSPMPAADSRVRAGRGRARVVAASGRIPAVTRSRACRHGVRPMKVSGARRASAAAAYPVAPRAQPRPRSRPAGDAAVQHAVAVARVAAARRRRGRGSAEPMPHEGAARSGARSCVAPRDRRACCVRRARASDESMRRFEAMLACNSS
>NC_008784.1|WP_004199157.1|27170_27842_-|transcriptional-regulator
MDDNFSKQEIPVSERVLNVLKRRGPLQAAELGAYLGTTGEAARQQLKKLEAEGLVEAQNVPQGVGRPARIWRLTSLGHGHFPDAHADMTVDLIRIIRTTLGQPTLDLLIAARETEMRRTYAHTLAGVTDPEERIARLAELRDREGYFAEWSRAPDGDGWLFIENHCPICAAATACQGFCRSELEIFREMLGDALTIERIEHIPAGARRCAYRIRPSGAGAGGE
>NC_008784.1|WP_004184876.1|27992_29090_+|efflux-RND-transporter-periplasmic-adaptor-subunit
MGRRLLLALALLAFIFGGLFLWRESRVQAADHPPAPPAALTVSAVAVRAAPERVTLDAVGSLDAVRQVTLAPEVAGRVVALQFDAGSAVRKGQLIVQLFDEPERAKLASIQAKAAYAKRQLDRSQALAQTGAEPRNLFDRHRFDFDAAAADIRETQAVITQKAVRAPFDGVLGLRRVNLGQYLNAGDAIATLTDLDTLYANFTVPQKNLSQLRLGQSVSITTDAYPERTLVARVSAIEPQIGTDTRNVAVQATLPNPDHLLRPGMYIQARLELPPRERALTVPDTAVQTSQRGESVLVVGKPGRDGLGVVRLQPVRTGRRADGRIAIADGLRPGDVVVTSGQVRLAAGDRVKVALDDGAGSGAAQ
>NC_008784.1|WP_004199160.1|29086_32188_+|MMPL-family-transporter
MNAGAPHDSGAARARFTDVFVRRPVLSLVFSLLILLVGLRALMSLPVRQYPALESATISVATDYPGASQELMQGFVTTPIAQSIATADGIEYITSTTTQGKSVVKARLRLNANADRAMTEVMAKVQQVKYKLPADAYDSVITKLTDAPTAVMYLGFASDALSIAQITDYVVRVAQPLVTTVPGVASAEILGGQNLAMRVWLDATRLAAHGLSAGDVAAAIRANNVQAAPGQVKGSLTIADISANTDLTDVGAFNEMVVKSAPNGGGLVRLKDVATVEIGGENYNSSALMNGRRAVYIAVNATPAGNPLEIVRGVGAVLPAIERNKPASVQIANMFDGARFVNASIAEVRSTLTEAIAIVVVVIFLFLGSFRAVIIPVLTIPLSLVGSAALMLAAGFSLNLLTLLAMVLAIGLVVDDAIVVVENIHRHIEQGEPPVRAALIGAREIASPVLVMMATLISVYAPIGLMGGLTGLLFKEFAFTLAGAVLVSGIVALTLSPMLGSLLLTSRMSEGRVAKAIERTLERVTHAYRRGLHASLAARPAILLIGAGVLAGIVLLFSGVKRELAPQEDQGSIMVAVKAPQYANLDYMERYAPDIERVFRTLPEADTSFILNSYGGSNLGFAGVNLVDWDKRTRSAAALQALIQARGDGIRGERVFAFQLPALPASSGGLPIQMVLRTPSGFADLYAQMERIKAAAQKSGLFAVLDSDLTFDSRAVGVTIDRNQANTLGVTMKDIADTLAVLVGENYVNRFNFKGRSYDVIPQVSRSERLSSEMLSRYYVKTGSGRMIPLSTVIQVTNGSQANALSQFNQMNAATFSAVPAPGVTMGDAVAFLEAQKLPAGFSIDWLGESRQYVQEGNRLAVTFGFALIVIFLVLAAQFESLRDPLVILVSVPLSICGALAPLYLGFATLNIYTQIGLVTLIGLISKHGILMVSFANDLQRHEGLDRRAAIERAAAVRLRPILMTTAAMVAGLVPLVFAAGAGAASRFAIGITVSTGMLVGTLFVLPTVYTFVAKDHGAAMRSERAQLLAATR
>NC_008784.1|WP_004266238.1|32322_33861_+|efflux-transporter-outer-membrane-subunit
MRTAVRAAAVAAAFFAAGCTLAPRYERPAAPVSGAFPADGVYAAQPGAAPGARSANGQAAVDIGWREFFVDPRLQRLIEIALKNNRDLRVSVLNVEASRAQYQITRAGLFPTLSGTGTGTIQRTPAGVSITGQPLISRTYNVGVSASWELDLFGRVQSLKDQALAQYFATAQARKAAEISLVASVADQYLTLLSTDDLLQVTQNTLKSARASYDLTKLQFDNGTGSELDLRQAQTVVETALASQQAQARARAQALNALVLLIGEPLPDDLPADLPLNAQNLLTDIPAGLPSDLLTRRPDIMQAEETLRAANANIGAARAAFFPKISLTSAFGTASTTLGGLFKAGTAAWSFAPNIALPIFEGGQNIANLDLAHVQKRIEIANYEKAIQSAFREVSDGLAARGTYDQQIAALERNEHAQQRRYDLSDLRYRNGVDSYLSVLTAQTDLYSAQQQLISARLARWTNLVDLYRALGGGWLERAGETPRPADAPVDYGKAAPAPAASASARTAAVIG
>NC_008784.1|WP_073699266.1|33857_34172_+|hypothetical-protein
MSAQPDMRQPNARQHSARRPSAARAGRERIGRTWRTKKKTDREMIGDTVIGTDAQSAMLLHNRTQQPIKSSPRTRETATNRKSIQAFDITIQKLPCSSRCVSQC
>NC_008784.1|WP_004539149.1|34190_34835_+|GTP-cyclohydrolase-II
MNDGRISPTMSASVRTRVNVPIRPRTAQQRFDAEMVTFQGLCDSAEHLALVFGPLADAPLVRVHSECLTGDVFGSARCDCGEQLDESVAMFGREGGILLYLRQEGRGIGLYNKLDAYRLQISQGLDTFAANRALNFPDDLRDFRVAAQMLQALGVTEISLVTNNPDKVSQIEKHGIRIRRVLQTGVFVNTTNHGYLRAKIDHHRHAINLSQELQ
>NC_008784.1|WP_004197695.1|34831_36529_+|WD40-repeat-domain-containing-protein
MITHRAPISGIAAHRDQYVLTAGYDNQVILWDAKTQRPLARAMHDHLANQGAFSPDGAYVVTSSSDYSARLWTVPDLRLVAVFADQEDDVEMSVFHPDKPLVATASRDHRVRVYDFGGKLLHTFSGHTADVISVEWMRGADEIVSSSDDGTIKRWSLANNGLVADIDLDGIETDTIAIAADGRIFAGNDEGEIISIGVDGARATIAAHDAGVKRLVLDGERGLLVSLSYDRTMRLWKVGAAGEPRALGGAALPPEVWPRSCSFEGDEHIVFSTFHSSYRRYNWKTERWDAAELPPTHGVNAVQPVDGHLWTIGDAGIVRVDQREHARTGSLCNFLAPAGELILTGGQLGKVFDARSGRELHQHRSPLNCGVAFARDGAAHAVIGTYTGEGIVLRIDGTRATHVADLPLHANAVKGIAISGDLIFSVAADASATWYRASTLEPAFELKRAHDKIANGCAGLGDGYFASVSRDLKLRIWSPDSHAEVIATPHTHSIKCVAASADGRYVATGSYNGRVAVYDRVETRWALDARVTTAGVSSLAYDPAARAFLASSYDGNVYRIPLERA

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Crispr_ID: NC_008784_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_008784_2

1056180-1056325

Orphan

Consensus_repeat	Method
GCAGAGGCGCCGCCGCCGGAATACCCGATCATCGGGATGCTCGATCGCCGAAG	PILER-CR
CGGAATGCCCGATCATCGGGATGC	CRISPRCasFinder

2 spacers

The CRISPR arrays of NC_008784_2

>merge|NC_008784|2|1056180-1056325|PILER-CR,CRISPRCasFinder
TCGTCGGGATGCTCGATTGCCGCAGTCACCCTCCGCCGGGGCTCCGTCGTCGGAATGCCCGATCATCGGGATGCCTGCTCGCCGAAGCACTCCACCGCAGAGGCGCCGCCGCCGGAATACCCGATCATCGGGATGCTCGATCGCCG

>NC_008784|2|2|1056180-1056325|PILER-CR
TCGTCGGGATGCTCGATTGCCGCAGTCACCCTCCGCCGGGGCTCCGTCGTCGGAA	TGCCCGAT
CATCGGGATGCCTGCTCGCCGAAGCACTCCACCGCAGAGGCGCCGCCGCCGGAAT	ACCCGATCA
TCGGGATGCTCGATCGCCG

>NC_008784|2|1|1056230-1056315|CRISPRCasFinder
CGGAATGCCCGATCATCGGGATGC	CTGCTCGCCGAAGCACTCCACCGCAGAGGCGCCGCCGC
CGGAATACCCGATCATCGGGATGC

Protein	Signature genes	Signature genes Name	Protein_function
NC_008784.1\|WP_011204701.1\|1067507_1067942_-\|Hsp20/alpha-crystallin-family-protein	unknown	unknown	gnl\|CDD\|223149
NC_008784.1\|WP_011204700.1\|1065536_1065911_+\|hypothetical-protein	unknown	unknown	unknown
NC_008784.1\|WP_004196898.1\|1046689_1047130_+\|SRPBCC-family-protein	unknown	unknown	gnl\|CDD\|176863
NC_008784.1\|WP_011204697.1\|1050725_1052384_+\|GMC-family-oxidoreductase	unknown	unknown	gnl\|CDD\|225186
NC_008784.1\|WP_004205322.1\|1048877_1049813_+\|LysR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|176109
NC_008784.1\|WP_004187469.1\|1055100_1055496_-\|conjugal-transfer-protein-TraR	unknown	unknown	gnl\|CDD\|224648
NC_008784.1\|WP_011204702.1\|1068347_1069475_-\|porin	unknown	unknown	gnl\|CDD\|238208
NC_008784.1\|WP_011204696.1\|1049994_1050426_+\|hypothetical-protein	unknown	unknown	unknown
NC_008784.1\|WP_004187216.1\|1052694_1054968_-\|pyridine-nucleotide-disulfide-oxidoreductase	unknown	unknown	gnl\|CDD\|369639
NC_008784.1\|WP_004200700.1\|1047464_1048580_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|378454
NC_008784.1\|WP_004187137.1\|1065883_1066333_-\|CBS-domain-containing-protein	unknown	unknown	gnl\|CDD\|341411
NC_008784.1\|WP_004187305.1\|1062643_1063675_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|236122
NC_008784.1\|WP_004187792.1\|1063671_1065504_+\|STAS-domain-containing-protein	unknown	unknown	gnl\|CDD\|223732
NC_008784.1\|WP_004188034.1\|1056882_1058148_+\|polyhydroxyalkanoate-depolymerase	unknown	unknown	gnl\|CDD\|130908
NC_008784.1\|WP_011204695.1\|1045640_1045967_+\|hypothetical-protein	unknown	unknown	unknown
NC_008784.1\|WP_009950893.1\|1046298_1046604_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|240624
NC_008784.1\|WP_004200705.1\|1066786_1067440_+\|SagB/ThcOx-family-dehydrogenase	unknown	unknown	gnl\|CDD\|380318
NC_008784.1\|WP_004553972.1\|1058453_1060238_+\|ribonucleotide-reductase	unknown	unknown	gnl\|CDD\|180772
NC_008784.1\|WP_004187710.1\|1060312_1062115_+\|bifunctional-aminoglycoside-phosphotransferase/ATP-binding-protein	unknown	unknown	gnl\|CDD\|225098
NC_008784.1\|WP_009927403.1\|1048640_1048751_-\|hypothetical-protein	unknown	unknown	unknown

Protein	Function_ID	Function_description	E-value
NC_008784.1\|WP_011204701.1\|1067507_1067942_-\|Hsp20/alpha-crystallin-family-protein	gnl\|CDD\|223149	COG0071, IbpA, Molecular chaperone (small heat shock protein) [Posttranslational modification, protein turnover, chaperones].	2.04683e-32
NC_008784.1\|WP_004196898.1\|1046689_1047130_+\|SRPBCC-family-protein	gnl\|CDD\|176863	cd07821, PYR_PYL_RCAR_like, Pyrabactin resistance 1 (PYR1), PYR1-like (PYL), regulatory component of abscisic acid receptors (RCARs), and related proteins. The PYR/PYL/RCAR-like family belongs to the SRPBCC (START/RHO_alpha_C/PITP/Bet_v1/CoxG/CalC) domain superfamily of proteins that bind hydrophobic ligands. SRPBCC domains have a deep hydrophobic ligand-binding pocket. PYR/PYL/RCAR plant proteins are receptors involved in signal transduction. They bind abscisic acid (ABA) and mediate its signaling. ABA is a vital plant hormone, which regulates plant growth, development, and response to environmental stresses. Upon binding ABA, these plant proteins interact with a type 2C protein phosphatase (PP2C), such as ABI1 and ABI2, and inhibit their activity. When ABA is bound, a loop (designated the gate/CL2 loop) closes over the ligand binding pocket, resulting in the weakening of the inactive PYL dimer and facilitating type 2C protein phosphatase binding. In the ABA:PYL1:ABI1 complex, the gate blocks substrate access to the phosphatase active site. A conserved Trp from PP2C inserts into PYL to lock the receptor in a closed formation. This group also contains Methylobacterium extorquens AM1 MxaD. The mxaD gene is located within the mxaFJGIR(S)ACKLDEHB cluster which encodes proteins involved in methanol oxidation. MxaD may participate in the periplasmic electron transport chain for oxidation of methanol. Mutants lacking MxaD exhibit a reduced growth on methanol, and a lower rate of respiration with methanol.	3.1145e-25
NC_008784.1\|WP_011204697.1\|1050725_1052384_+\|GMC-family-oxidoreductase	gnl\|CDD\|225186	COG2303, BetA, Choline dehydrogenase and related flavoproteins [Amino acid transport and metabolism].	4.76839e-37
NC_008784.1\|WP_004205322.1\|1048877_1049813_+\|LysR-family-transcriptional-regulator	gnl\|CDD\|176109	cd08417, PBP2_Nitroaromatics_like, The C-terminal substrate binding domain of LysR-type transcriptional regulators that involved in the catabolism of nitroaromatic/naphthalene compounds and that of related regulators; contains the type 2 periplasmic binding fold. This CD includes the C-terminal substrate binding domain of LysR-type transcriptional regulators involved in the catabolism of dinitrotoluene and similar compounds, such as DntR, NahR, and LinR. The transcription of the genes encoding enzymes involved in such degradation is regulated and expression of these enzymes is enhanced by inducers, which are either an intermediate in the metabolic pathway or compounds to be degraded. Also included are related LysR-type regulators clustered together in phylogenetic trees, including NodD, ToxR, LeuO, SyrM, TdcA, and PnbR. This substrate-binding domain shows significant homology to the type 2 periplasmic binding proteins (PBP2), which are responsible for the uptake of a variety of substrates such as phosphate, sulfate, polysaccharides, lysine/arginine/ornithine, and histidine. The PBP2 bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap. After binding their specific ligand with high affinity, they can interact with a cognate membrane transport complex comprised of two integral membrane domains and two cytoplasmically located ATPase domains. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis.	7.67997e-62
NC_008784.1\|WP_004187469.1\|1055100_1055496_-\|conjugal-transfer-protein-TraR	gnl\|CDD\|224648	COG1734, DksA, DnaK suppressor protein [Signal transduction mechanisms].	1.7869e-14
NC_008784.1\|WP_011204702.1\|1068347_1069475_-\|porin	gnl\|CDD\|238208	cd00342, gram_neg_porins, Porins form aqueous channels for the diffusion of small hydrophillic molecules across the outer membrane. Individual 16-strand anti-parallel beta-barrels form a central pore, and trimerizes thru mainly hydrophobic interactions at the interface. Trimers are stabilized by hytrophillic clamping of Loop L2. Loop 3 bends into the pore, creating an elliptical constriction of about 7 x 11A, large enough to allow passage of a glucose molecule without steric hindrance. Removal of the C-terminal residue (usuallly F) destabilizes the trimer and removal of the 16th beta-sheet abolishes trimerization. Unlike typical membrane proteins, porins lack long hydrophobic stretches. Short turns are found at the smooth, periplasmic end, longer irregular loops are found at the rough, extracellular end. C-terminal residue forms salt bridge with N-terminus.	3.6975e-55
NC_008784.1\|WP_004187216.1\|1052694_1054968_-\|pyridine-nucleotide-disulfide-oxidoreductase	gnl\|CDD\|369639	pfam07992, Pyr_redox_2, Pyridine nucleotide-disulphide oxidoreductase. This family includes both class I and class II oxidoreductases and also NADH oxidases and peroxidases. This domain is actually a small NADH binding domain within a larger FAD binding domain.	7.15563e-57
NC_008784.1\|WP_004200700.1\|1047464_1048580_-\|hypothetical-protein	gnl\|CDD\|378454	pfam10604, Polyketide_cyc2, Polyketide cyclase / dehydrase and lipid transport. This family contains polyketide cylcases/dehydrases which are enzymes involved in polyketide synthesis. It also includes other proteins of the START superfamily.	2.16274e-11
NC_008784.1\|WP_004187137.1\|1065883_1066333_-\|CBS-domain-containing-protein	gnl\|CDD\|341411	cd17775, CBS_pair_bact_arch, Two tandem repeats of the cystathionine beta-synthase (CBS pair) domains present in bacteria and archaea. The CBS domain, named after human CBS, is a small domain originally identified in cystathionine beta-synthase and is subsequently found in a wide range of different proteins. CBS domains usually occur in tandem repeats. They associate to form a so-called Bateman domain or a CBS pair based on crystallographic studies in bacteria. The CBS pair was used as a basis for this cd hierarchy since the human CBS proteins can adopt the typical core structure and form an intramolecular CBS pair. The interface between the two CBS domains forms a cleft that is a potential ligand binding site. The CBS pair coexists with a variety of other functional domains and this has been used to help in its classification here. It has been proposed that the CBS domain may play a regulatory role, although its exact function is unknown. Mutations of conserved residues within this domain are associated with a variety of human hereditary diseases, including congenital myotonia, idiopathic generalized epilepsy, hypercalciuric nephrolithiasis, and classic Bartter syndrome (CLC chloride channel family members), Wolff-Parkinson-White syndrome (gamma 2 subunit of AMP-activated protein kinase), retinitis pigmentosa (IMP dehydrogenase-1), and homocystinuria (cystathionine beta-synthase).	1.39507e-50
NC_008784.1\|WP_004187305.1\|1062643_1063675_+\|hypothetical-protein	gnl\|CDD\|236122	PRK07877, PRK07877, Rv1355c family protein.	5.74738e-30
NC_008784.1\|WP_004187792.1\|1063671_1065504_+\|STAS-domain-containing-protein	gnl\|CDD\|223732	COG0659, SUL1, Sulfate permease and related transporters (MFS superfamily) [Inorganic ion transport and metabolism].	2.60835e-107
NC_008784.1\|WP_004188034.1\|1056882_1058148_+\|polyhydroxyalkanoate-depolymerase	gnl\|CDD\|130908	TIGR01849, unnamed_protein_product, polyhydroxyalkanoate depolymerase, intracellular. This model represents an intracellular depolymerase for polyhydroxyalkanoate (PHA), a carbon and energy storing polyester that accumulates in granules in many bacterial species when carbon sources are abundant but other nutrients are limiting. This family is named for PHAs generally, rather than polyhydroxybutyrate (PHB) specificially as in Ralstonia eutropha H16, to avoid overcalling chemical specificity in other species. Note that this family lacks the classic GXSXG lipase motif and instead shows weak similarity to some [Fatty acid and phospholipid metabolism, Degradation].	1.36366e-112
NC_008784.1\|WP_009950893.1\|1046298_1046604_-\|hypothetical-protein	gnl\|CDD\|240624	cd05299, CtBP_dh, C-terminal binding protein (CtBP), D-isomer-specific 2-hydroxyacid dehydrogenases related repressor. The transcriptional corepressor CtBP is a dehydrogenase with sequence and structural similarity to the d2-hydroxyacid dehydrogenase family. CtBP was initially identified as a protein that bound the PXDLS sequence at the adenovirus E1A C terminus, causing the loss of CR-1-mediated transactivation. CtBP binds NAD(H) within a deep cleft, undergoes a conformational change upon NAD binding, and has NAD-dependent dehydrogenase activity.	0.0059154
NC_008784.1\|WP_004200705.1\|1066786_1067440_+\|SagB/ThcOx-family-dehydrogenase	gnl\|CDD\|380318	cd02142, McbC_SagB-like_oxidoreductase, oxidase similar to the microcin B17 processing protein McbC. This family is the oxidase domain of NRPS (non-ribosomal peptide synthetase) and other systems that modify polypeptides by cyclizing a thioester to form a ring. These include EpoB, part of the epothilone biosynthesis pathway; TubD, part of the tubulysin biosynthesis pathway, MtsD, part of the myxothiozol biosynthesis pathway; IndC, part of the indigoidine biosynthesis pathway and TfxB, part of the trifitoxin processing pathway. All are FMN-dependent and oxidize the product of the cyclization of thioesters in short polypeptides.	6.31252e-20
NC_008784.1\|WP_004187710.1\|1060312_1062115_+\|bifunctional-aminoglycoside-phosphotransferase/ATP-binding-protein	gnl\|CDD\|225098	COG2187, COG2187, Uncharacterized protein conserved in bacteria [Function unknown].	9.00049e-75
NC_008784.1\|WP_004553972.1\|1058453_1060238_+\|ribonucleotide-reductase	gnl\|CDD\|180772	PRK06948, PRK06948, ribonucleotide reductase-like protein; Provisional.	0

>NC_008784.1|WP_004187469.1|1055100_1055496_-|conjugal-transfer-protein-TraR
MAAFDEHQLQVLGALLRACRQALQADVRAGERQRADEPYANLAGPAPDEGDEANADLFVDVDHALLGMKLAELRDVDAALQRIARRDYGCCADCGQPIAYERLLARPTALRCAPCQRAHERRFATQPRPSL
>NC_008784.1|WP_004187216.1|1052694_1054968_-|pyridine-nucleotide-disulfide-oxidoreductase
MREFDYLLVGGGIASVTAARTLRGEDASASIAILCGEPVLPYQRPPLSQEWLMGAVQPASITLHDAAFYAAQRIDIALGVRAEQLDRAKRIVRTSSGATFRYGKLLIATGASAKAPALPGFGLDGVHVLHTFAQAQALKDAAAHARRATVLGGGFLGVEIAATLQALGLQVTLVERAPGVMPSLRAPALGGHFEALCRARGIDVLTRCEVRRVLGAQCVEAVETSDGGTRPCDLFVAAVGVTPNCGWLDGSGLALGDGVEVDAFLQTADPDVFAAGDVAHFDDPIFGVRRRIEHWDNAVRQGRIAARNMLGHRLPYRDVSIFYGSVFGLSYNLLGYPVGATETIERGAFDEASYMQLYLADDVLRAAFTIDRPAVEIAALNDAIRLHVNVAAHKMKLSDPNYPLDKLPVQTILILQGGGALGAFECGAVKALEQHGVRPDVISAVSIGAFNGAIVASHPKGATKALEAFWRELSIALPLPYESQWREAWLSSYVLSFGVPNFLKPQWSQLGFDADRLRAKWTSFFDATAIEQLIARYVDFDSLGMSPTRLLIGAVDVETGEPRIFDSYVDRLSPAHVLASGSLPPGMPWTVVDGRPYWDGGVVSNSPLDLVIARCGQIGGRVFIVDLFSGSKALPTNLVEVMLRREEIAYMDRVRNDLRFEEYASDFRDLVDGILAHVDAPSANEIRQQPLYIRLMGNRAAIDIARITLNREGRLSFIEDYDFSSDAIAQLQQQGYDAALVALANGRSRRRRGRRRA
>NC_008784.1|WP_011204697.1|1050725_1052384_+|GMC-family-oxidoreductase
MKQQSYDYDYVVVGSGFGGSVSALRLSEKGYRVLVIEQGRRWTPENLPESTWNLSRWQWRPALGLHGFFSMRFFRHVVVLHGNAVGGGSITYANTLLVPPNKVWREGTWAGLEDWERVMPAHYATAKRMLGVVTNRRMDAADFRLKDMAKLIGVEKSFYPTEVGVFFGDDADAPGTRYADPYFGGAGPERTSCIGCGGCMVGCRHGAKNTLDRNYLYLAERLGAQVREQTKVVDVRPLDARADGAAGYAVEAVSLAAGARGAKSRLTCRGVVFAASSLGTQDLLMRLKEKGSLPRLSDALGKRVRTNAESLIGVRFPKSRVDLSKGVAIGSGIYIDEHTHIEATRYPSGSDTMGLLTTVLTRGAPGGLRVLVWLGALAKLVLTRPLSAWRMIDPRGFARETMIFLCMQTLEGHLTMRLKRRWFWPFSKQLATSGAKIPAYIPAANDFAQKAARALGGVPMTSLTEILLNVPMTAHCMGGAAMARDARDGVCDGRSRVFGYRNMYVCDGSVLGANLGVNPSLTITALAEHAMSHVPAAREQRWDSTAETPVAA
>NC_008784.1|WP_011204696.1|1049994_1050426_+|hypothetical-protein
MHQERRKRNADRHGTHPYDADSRAAPREAPRFEHEPKKQRDAAQHEVDRDRAAREIHERIEHKARPDVRRAERPISQDVAQTPIGAAGAISPSTARSIFLEIGLALAGRPIQVRRNRAPFTHGTPRRRPARGPTARTASPAPV
>NC_008784.1|WP_004205322.1|1048877_1049813_+|LysR-family-transcriptional-regulator
MIQNLRQLDLNLLLVFDALMQEQNLSRAAIRLHMSQPAVSNALTRLRQQLGEPLFTRTARGMTPTAQARTLYEPVRQALYLLQIGLGPQADFEPDTHHLFKLSMNDYGQTVLLPDLLAHIKSRAPNVMLSVQSDDAGSIPAQLTTGTLDLAIDYLHFDNPELCYEPLHEEHLVVIGRAGHPAFAGGLALRGYEESGHVSIQPRDRRGSPLEIVLGSARVRRVVHLQVPHYLTIPALVAKSDLLGTIPRRLAERFADVYALQIAPLPIDIAPIQVSLIWHRQQDAQPGLRWLREQVVLTHRAIIGCGEHAPA
>NC_008784.1|WP_009927403.1|1048640_1048751_-|hypothetical-protein
MQSTGSFDISARRMIEFRSVNKSNHDCPLEKSSGLL
>NC_008784.1|WP_004200700.1|1047464_1048580_-|hypothetical-protein
MTQDVTVFRARYRASVHPRYNAWLHGGFVLAYGCAAIAFFLKDVARVSAVQWASVPAAFLLFNWLEFTVHRHVGHVKRRFGAMFYRRHTGDHHSFFANEQIAYREARDWRVILFPAWLIVVFSLGLFALHAVLGRFDANVAGLFASTMLGGYLLYECVHACEHLPDAHPLAKWPWIRQMRVLHRVHHRDALMRSCNFDVIWPLMDWLHGTLRWSEAPGADMSTRMRHEIDIACAGADVLAYASDASRWPEWHPSSLRVDGPAGSLAAGSRFDEDVRAAGRVDRLHWDVVRNEPGVMWQARAANTAGSLRILLTYECSGGPRGARFVRTLHYHSPNPLLRLANALVMRGRVERESAYSLTLLKRRLEAARDA
>NC_008784.1|WP_004196898.1|1046689_1047130_+|SRPBCC-family-protein
MKQQRIEIAEEFDAPVHQVFRFFSEHENLKSIFSPAKIRRISDGEPARNGVGSAREMRVPGAPPFVETVTAYQENELIEYRITRGSPLRDHLGVMRFVPIDERRTYFHYVITFEGKVPFVAPVVRHVLEGSIRRGLGKVATRRLWG
>NC_008784.1|WP_009950893.1|1046298_1046604_-|hypothetical-protein
MRHDSRLRCTRDDDDIDQCHRQSGRSPLDAEPNRGCAARRLRASGGRRPRGANTEPRRRKPHARVIRQRSWRAARTRPCRRFSAACGRFGQAMARRARPPA
>NC_008784.1|WP_011204695.1|1045640_1045967_+|hypothetical-protein
MRHACRACGPRVRRTRFCAMRKRSETHGRSLSLSLAHRATDARCARCPHSRHELCTRARAPARERRRCIASRISLITTINFRAVAFRPRLPKHYIDRWNHRSAGTPAA
>NC_008784.1|WP_004188034.1|1056882_1058148_+|polyhydroxyalkanoate-depolymerase
MLYAWLEAQREFFRACQPWAGAAQRAGAGARPAGWPTWGPMARAADAVPAPPPFAIASIEIDGAAVPVDECVVDDTPFCALRKFSRRLRGDAAARPAVFLCTPLAGHHAVMLRETVETILATRDVYVTDWRNARDVPPEAGAFGLDDYVCTLERFVAGAAGDGLHMMAVCQATVPALAAVALLAARDVHVTSVALLGGPVDTRSHPTLIDRFALEHDLDWFRRTAIDIVPPPYAGAGRRVYPGFIQHAAIIVAHPQRRASLESRYWTAWMTGDFAAAARCLREMNEYGAVLDMTERYFLDTIRVIFHERLLAQGRWSIGRRLVAPRRLTRTALCTIEGGRDDIAGAGQTHAAHALCDAVPDAVRERITEPDCDHYDLFLGPRWRRTIHPALDAFWTRAEAARAAAGEPRPTAERAERRIAH
>NC_008784.1|WP_004553972.1|1058453_1060238_+|ribonucleotide-reductase
MIGDMDDQPICDAVFADRYALPGEHSRAQACARVARALALAEPMATRSGAARRFYRNLLNGAFGAGRIMARAGAAPDQTMASCFVHPIRAPAALTRFHPNLDEALDEARLALAMGADIGYDFSAIPPAGARPDADHPDSPGVCAALDRFDRIGTQAGERDGRRRAQLAVLRCDHPDLLAFAAAKHRHAGRHARWTTLELAVAATDAFMQAVEQDLPWTLRHTAPPRDAPGGALPGADGAWTYASVPARHVWREIVSAARDGAGPGLVFVDAIDAADPLRGRERIDATSPCGAQPLPPYGSAMLGAIDLSRFVRNPFGAGGEPRFDFAAFDTAVRIEVRLLDNALDVTRWPLAAHARESYQKRRIGVGVTGLADMLAMMRLRYDSPAAREMARYIASDLRHHAYAASAELAAERGAYPLCDRHAHLDALRAGPPLPHAVCHAIERDGLRHSHLTSFAPVIGVSLAFGDHCSPGIEPARAWIEHRPVRAGAAGAPGMRAENHAHRLFRSLRGERAALPDYFATDADVAPGERLAMRVALQPYVDAGIDNTLTLANHYSLEEVNALLFAAWRAKLKSVAIRRADLARDAQPSDDDGV
>NC_008784.1|WP_004187710.1|1060312_1062115_+|bifunctional-aminoglycoside-phosphotransferase/ATP-binding-protein
MTTGAVAARRLPRRGTARGRRAPSRAFTIHGGDEMRRSRPPKPAKPAAVRRRPHGAARAHAIRGNGPQRRAVRERAARRLSRDIDAALRRASTYPHPAGPIVRIETHLSVVYLVGRFAYKRLKPFDFGFANFTELAARRRACEAELALNRPLAAPIYLAAGPLVRRARGLRLFGAGAAVDHVVRMRRFDERMLFSRLLARGALDAADIDAAATRLAAYHLHAPRDIPRRAYGSARELRRQLDDMLAPLERALGAALPASLRAWCVRRCDELAAHLDARRADGYVRACHGDLHLNNVVKRGRDALMFDCIDFDDALRWIDVINDLSFLLMDLHAHDRAALAHRLLNRWLDETGDFAGLAALPLYVAYRALVRALVATMRAGGDAAARAARIERARRYVDVAAHAARARRPCLLLCHGYSGSGKSVASRALADVSGAIRLSSDSERKRARPFAAVDARPLPASAYTPQQIDAQYERLRALARDVLRAGYTALVDATFLSHARRARFFALARELGVPVYVLDFHASRACLERRVDARAAARDDRSDAGAAVLATQRASADPLDADERARTIGFDTDVPLATLRSAGYWRPVLDAARVDAQATR
>NC_008784.1|WP_004187305.1|1062643_1063675_+|hypothetical-protein
METSPLKTTTPEAIPPFNPSASVEDKLRLAIHYAILAPSSHNTQPWRFMVGDGSVMLCADRLRALSVVDPYDRELLISCGAALLNLRVALSRFGFAYVIDMFPSPSDPDVIALVRLDPHGYHDESLVPLFDAILERVTTRTPYANEAVPCDVQRALVDAGAAEGAEIACVDAPHALDEIAELIADADRLQFADPRFRRELANWVHPRRHDDGMPAFAAGVPALLDFATPVVASAIRTFDLGGGLAAMHHKLVDGSPLIVGISTASDDRDAWVATGQALERVLLVAAAAGLTASYLNQPIEIDALRERLRPLLHVDAHPQLLLRIGRGPVVAHAPRRPLMDVVS
>NC_008784.1|WP_004187792.1|1063671_1065504_+|STAS-domain-containing-protein
MTERERAARGRNDARRGGGDSGGDDEAWRRWLPGIATLRTYRRAWLARDLYAGVALTAVLVPVGMSYAQAAGLPVIAGLNASIAALVGYAIFGPSRILVLGPDSALAALIAGAIAPLAHGEPAHAVALAAALALMSGGFCVLAGLLKLGFVTDLLSKPIQYGYLNGLALTLIASQLPSLLGTVPLGGTFVDQVASLAATVAQGRIDFASLALGGGCLAGIALLRRVAPAWPGMLIAVAGASIVAAWLGAAPDAGGAHAHVAYAHVANAHVALVGSLAGTLPPLGLPSISLADASRLIAGALAIAMVSVADISVLSHVFAQHDGSETDRNQELCALGAANLLAGMLRGCAVSSSASRTPVALAAGARTQLTSLVAAACIALLLIAPTLLARVPLAALAAVVVYSANALVDVRAIVRLYRVRRGECAVSVLCFAGVVLLGVVPGILLAVGLSLLSFVWRAWHPYDAVLGRVEGMHGYHDVSRHPGATLTRGLVAFRWDAPLFHANATIFRDHVRDAIAEAGAPVRCVVIAAEPITDVDVTAADMLATLRDELAARRIALVFAEMKGPVKDRLRTYGLFEKIGADHFFPTVTDAIEHFTRMRKDVATARRARR
>NC_008784.1|WP_011204700.1|1065536_1065911_+|hypothetical-protein
MRARAPIRLGGSARLRSVDDDGAGAQAIEAVRRRHGIGHHDAVSVNAAQAARLRAVARTPNCALDRLDAARFAALRIDDVDISVAVALGIDINVAFPLDIDIDATRRETRRDDSIRQSRAFSSK
>NC_008784.1|WP_004187137.1|1065883_1066333_-|CBS-domain-containing-protein
MNAAEICTREVVACRRTDTVLDAAHLMRDRHVGDLIVVDDAGHAHAPVGMLTDRDIVLSLIAKEVDPAALFVGEIMSAPAAVVHEHDSLWTIAQRMRLTGVRRMPVVNADGALVGMVSVDDLLASVAALFDEIASISRRQIHFEEKARD
>NC_008784.1|WP_004200705.1|1066786_1067440_+|SagB/ThcOx-family-dehydrogenase
MSDPELLTYQPIAVALPGPAEAGAPAVIDLPPPDLGAGLPLMSALSLRASTREFSSAALAPTTLGELLWAADGVNRPTTGGRTAPSAHAFNEIDIYAALPDGVYRYDAALHRLLLKHAVDARNLTGYQDFVGAAPLDLIYVVRMSRLLSMPKPLRETFSAVAAGAIAQNVALYCASTGLGCVVRGWINHRLLAEALSLNEDELPILAQTVGKPAAHP
>NC_008784.1|WP_011204701.1|1067507_1067942_-|Hsp20/alpha-crystallin-family-protein
MSNVTRYDPFSLEPVSDLFRGLFRPLRGIADADDEKLASMKIDVTENDQAYAVKAELPGVDKNDINVQIDGNTVSISAKVERNKELKEGERVIRRERYSGEFARTFSLANELDRDAASAQYQDGVLSLTLPKKASSEKKKLTIG
>NC_008784.1|WP_011204702.1|1068347_1069475_-|porin
MNAKSIAAAALAVAQAGLAHAQSSVTLYGALDAGVLWQNTSAASFSPTAPNTGAVVRFKDGGVYSSLWGIKGTEDLGGGYRVNFRLQGAFDGGTGKFGLSDAPGAVAAFNQIATLGVSGPFGTFNAGRQIVPMIYAMADTDVRAARFFGSVLTAWLGLNTAAGWPGNSTNAPIGALYDSDALVYQSPAFGGASLALEYAPGGVPGGVQRGARASIVLKYASNALNLAAVYYNGHDTNPAPGASATGLDNNRFVYVGAQYKLKDVAVSASYGNGRNPARGDRVNLDMFAFGLGYRVSPFFRVSSGVYYLKDRNRSANRSTSIVLGADYELSKHTTLYAQGGRVDNRGTMAQMLAYGQPVAPGLATTAAMLGMRHSF

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Crispr_ID: NC_008784_3

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_008784_3

1288637-1288729

Orphan

Consensus_repeat	Method
TCGCCGCCGCGCGCGACGACGCGC	CRISPRCasFinder

1 spacers

The CRISPR arrays of NC_008784_3

>merge|NC_008784|3|1288637-1288729|CRISPRCasFinder
TCGCCGCCGCGCGCGACGACGCGCTGAAGGACGCGCTCGCGCAGGCCGCCGCCGAGCGCGAGCGGCTGATCGCCGCCGCGCGCGCCGACGCGC

>NC_008784|3|2|1288637-1288729|CRISPRCasFinder
TCGCCGCCGCGCGCGACGACGCGC	TGAAGGACGCGCTCGCGCAGGCCGCCGCCGAGCGCGAGCGGCTGA
TCGCCGCCGCGCGCGCCGACGCGC

Protein	Signature genes	Signature genes Name	Protein_function
NC_008784.1\|WP_004188221.1\|1286227_1286683_+\|F0F1-ATP-synthase-subunit-epsilon	unknown	unknown	gnl\|CDD\|184057
NC_008784.1\|WP_011807573.1\|1288166_1288418_+\|F0F1-ATP-synthase-subunit-C	unknown	unknown	gnl\|CDD\|184067
NC_008784.1\|WP_044302747.1\|1294910_1296515_+\|methyl-accepting-chemotaxis-protein	unknown	unknown	gnl\|CDD\|185008
NC_008784.1\|WP_004188458.1\|1279890_1281069_-\|acetate/propionate-family-kinase	unknown	unknown	gnl\|CDD\|235922
NC_008784.1\|WP_004187376.1\|1296864_1298700_-\|response-regulator	unknown	unknown	gnl\|CDD\|237425
NC_008784.1\|WP_004188525.1\|1298849_1299974_-\|ABC-transporter-permease	unknown	unknown	gnl\|CDD\|223912
NC_008784.1\|WP_004187346.1\|1287468_1288170_+\|F0F1-ATP-synthase-subunit-A	unknown	unknown	gnl\|CDD\|237383
NC_008784.1\|WP_004188303.1\|1291173_1292022_+\|F0F1-ATP-synthase-subunit-gamma	unknown	unknown	gnl\|CDD\|376304
NC_008784.1\|WP_004187423.1\|1284404_1284662_-\|hypothetical-protein	unknown	unknown	unknown
NC_008784.1\|WP_004198321.1\|1292236_1293262_+\|alcohol-dehydrogenase-AdhP	unknown	unknown	gnl\|CDD\|176257
NC_008784.1\|WP_004201694.1\|1287163_1287472_+\|membrane-protein	unknown	unknown	gnl\|CDD\|274462
NC_008784.1\|WP_004187158.1\|1293899_1294409_-\|hypothetical-protein	unknown	unknown	unknown
NC_008784.1\|WP_004188840.1\|1282479_1284273_-\|alpha/beta-fold-hydrolase	unknown	unknown	gnl\|CDD\|213656
NC_008784.1\|WP_004188438.1\|1286679_1287171_+\|AtpZ/AtpI-family-protein	unknown	unknown	gnl\|CDD\|378198
NC_008784.1\|WP_004198323.1\|1296606_1296765_-\|hypothetical-protein	unknown	unknown	unknown
NC_008784.1\|WP_004198322.1\|1293338_1293842_+\|hypothetical-protein	unknown	unknown	unknown
NC_008784.1\|WP_004188355.1\|1289164_1291177_+\|F0F1-ATP-synthase-subunit-alpha	unknown	unknown	gnl\|CDD\|183987
NC_008784.1\|WP_004188073.1\|1284633_1286238_+\|F0F1-ATP-synthase-subunit-beta	unknown	unknown	gnl\|CDD\|183615
NC_008784.1\|WP_011204278.1\|1281065_1282496_-\|bifunctional-enoyl-CoA-hydratase/phosphate-acetyltransferase	unknown	unknown	gnl\|CDD\|236180
NC_008784.1\|WP_004188377.1\|1299976_1303192_-\|ATP-binding-cassette-domain-containing-protein	unknown	unknown	gnl\|CDD\|224054

Protein	Function_ID	Function_description	E-value
NC_008784.1\|WP_004188221.1\|1286227_1286683_+\|F0F1-ATP-synthase-subunit-epsilon	gnl\|CDD\|184057	PRK13447, PRK13447, F0F1 ATP synthase subunit epsilon; Provisional.	4.44077e-63
NC_008784.1\|WP_004187376.1\|1296864_1298700_-\|response-regulator	gnl\|CDD\|237425	PRK13557, PRK13557, histidine kinase; Provisional.	2.51413e-132
NC_008784.1\|WP_044302747.1\|1294910_1296515_+\|methyl-accepting-chemotaxis-protein	gnl\|CDD\|185008	PRK15048, PRK15048, methyl-accepting chemotaxis protein II; Provisional.	2.56608e-79
NC_008784.1\|WP_004188458.1\|1279890_1281069_-\|acetate/propionate-family-kinase	gnl\|CDD\|235922	PRK07058, PRK07058, acetate/propionate family kinase.	0
NC_008784.1\|WP_004188525.1\|1298849_1299974_-\|ABC-transporter-permease	gnl\|CDD\|223912	COG0842, COG0842, ABC-type multidrug transport system, permease component [Defense mechanisms].	6.54035e-26
NC_008784.1\|WP_004187346.1\|1287468_1288170_+\|F0F1-ATP-synthase-subunit-A	gnl\|CDD\|237383	PRK13421, PRK13421, F0F1 ATP synthase subunit A; Provisional.	1.54059e-122
NC_008784.1\|WP_004188303.1\|1291173_1292022_+\|F0F1-ATP-synthase-subunit-gamma	gnl\|CDD\|376304	pfam00231, ATP-synt, ATP synthase.	1.10329e-32
NC_008784.1\|WP_011807573.1\|1288166_1288418_+\|F0F1-ATP-synthase-subunit-C	gnl\|CDD\|184067	PRK13468, PRK13468, F0F1 ATP synthase subunit C; Provisional.	3.27869e-35
NC_008784.1\|WP_004198321.1\|1292236_1293262_+\|alcohol-dehydrogenase-AdhP	gnl\|CDD\|176257	cd08297, CAD3, Cinnamyl alcohol dehydrogenases (CAD). These alcohol dehydrogenases are related to the cinnamyl alcohol dehydrogenases (CAD), members of the medium chain dehydrogenase/reductase family. NAD(P)(H)-dependent oxidoreductases are the major enzymes in the interconversion of alcohols and aldehydes, or ketones. Cinnamyl alcohol dehydrogenases (CAD) reduce cinnamaldehydes to cinnamyl alcohols in the last step of monolignal metabolism in plant cells walls. CAD binds 2 zinc ions and is NADPH- dependent. CAD family members are also found in non-plant species, e.g. in yeast where they have an aldehyde reductase activity. The medium chain dehydrogenases/reductase (MDR)/zinc-dependent alcohol dehydrogenase-like family, which contains the zinc-dependent alcohol dehydrogenase (ADH-Zn) and related proteins, is a diverse group of proteins related to the first identified member, class I mammalian ADH. MDRs display a broad range of activities and are distinguished from the smaller short chain dehydrogenases (~ 250 amino acids vs. the ~ 350 amino acids of the MDR). The MDR proteins have 2 domains: a C-terminal NAD(P) binding-Rossmann fold domain of a beta-alpha form and an N-terminal catalytic domain with distant homology to GroES. The MDR group contains a host of activities, including the founding alcohol dehydrogenase (ADH), quinone reductase, sorbitol dehydrogenase, formaldehyde dehydrogenase, butanediol DH, ketose reductase, cinnamyl reductase, and numerous others. The zinc-dependent alcohol dehydrogenases (ADHs) catalyze the NAD(P)(H)-dependent interconversion of alcohols to aldehydes or ketones. Active site zinc has a catalytic role, while structural zinc aids in stability. ADH-like proteins typically form dimers (typically higher plants, mammals) or tetramers (yeast, bacteria), and generally have 2 tightly bound zinc atoms per subunit. The active site zinc is coordinated by a histidine, two cysteines, and a water molecule. The second zinc seems to play a structural role, affects subunit interactions, and is typically coordinated by 4 cysteines.	0
NC_008784.1\|WP_004201694.1\|1287163_1287472_+\|membrane-protein	gnl\|CDD\|274462	TIGR03165, F1F0_chp_2, F1/F0 ATPase, Methanosarcina type, subunit 2. Members of this protein family are uncharacterized, highly hydrophobic proteins encoded in the middle of apparent F1/F0 ATPase operons. We note, however, that this protein is both broadly and sparsely distributed. It is found in about only about two percent of microbial genomes sequenced, with the first ten examples found coming from the Euryarchaeota, Chlorobia, Betaproteobacteria, Deltaproteobacteria, and Planctomycetes. In most of these species, surrounding operon appears to represent a second F1/F0 ATPase system, and the member proteins belong to subfamilies with the same phylogenetic distribution as the current protein family.	3.23546e-10
NC_008784.1\|WP_004188840.1\|1282479_1284273_-\|alpha/beta-fold-hydrolase	gnl\|CDD\|213656	TIGR01838, Poly-beta-hydroxybutyrate_polymerase, poly(R)-hydroxyalkanoic acid synthase, class I. This model represents the class I subfamily of poly(R)-hydroxyalkanoate synthases, which polymerizes hydroxyacyl-CoAs with three to five carbons in the hydroxyacyl backbone into aliphatic esters termed poly(R)-hydroxyalkanoic acids. These polymers accumulate as carbon and energy storage inclusions in many species and can amount to 90 percent of the dry weight of cell. [Fatty acid and phospholipid metabolism, Biosynthesis].	6.3979e-179
NC_008784.1\|WP_004188438.1\|1286679_1287171_+\|AtpZ/AtpI-family-protein	gnl\|CDD\|378198	pfam09527, ATPase_gene1, Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter. This model represents a protein found encoded in F1F0-ATPase operons in several genomes, including Methanosarcina barkeri (archaeal) and Chlorobium tepidum (bacterial). It is a small protein (about 100 amino acids) with long hydrophobic stretches and is presumed to be a subunit of the enzyme. It carries two transmembrane helices and is a magnesium or calcium uniporter. The atp operon of alkaliphilic Bacillus pseudofirmus OF4, as in most prokaryotes, contains the eight structural genes for the F-ATPase (ATP synthase), which are preceded by an atpI gene that encodes a membrane protein with 2 TMSs. A tenth gene, atpZ, has been found in this operon, which is upstream of and overlapping with atpI.	7.77353e-17
NC_008784.1\|WP_004188355.1\|1289164_1291177_+\|F0F1-ATP-synthase-subunit-alpha	gnl\|CDD\|183987	PRK13343, PRK13343, F0F1 ATP synthase subunit alpha; Provisional.	0
NC_008784.1\|WP_004188073.1\|1284633_1286238_+\|F0F1-ATP-synthase-subunit-beta	gnl\|CDD\|183615	PRK12597, PRK12597, F0F1 ATP synthase subunit beta; Provisional.	0
NC_008784.1\|WP_011204278.1\|1281065_1282496_-\|bifunctional-enoyl-CoA-hydratase/phosphate-acetyltransferase	gnl\|CDD\|236180	PRK08190, PRK08190, bifunctional enoyl-CoA hydratase/phosphate acetyltransferase; Validated.	0
NC_008784.1\|WP_004188377.1\|1299976_1303192_-\|ATP-binding-cassette-domain-containing-protein	gnl\|CDD\|224054	COG1131, CcmA, ABC-type multidrug transport system, ATPase component [Defense mechanisms].	1.59115e-92

>NC_008784.1|WP_011807573.1|1288166_1288418_+|F0F1-ATP-synthase-subunit-C
MNNLIEVVSIAAAALAVSFGAIGPALAEGRAVGAAMDAIARQPDASGTVSRTLFVGLAMIETMAIYCLVVALLLLLFANPFVK
>NC_008784.1|WP_004187346.1|1287468_1288170_+|F0F1-ATP-synthase-subunit-A
MNASPLSTVPLFSVGPVGISAPVLATWAIMAVLVALALVARRRLSVDAPSRLQSVLELFVATVDAQIADTMQTPPARYRALIGTIFVLVFCANGASLVPGVEPPTAHLETDAALALVVLAATLYYGVRARGVRGYLATFAEPTWVMIPLNVVEQLTRTFSLIVRLFGNVMSGVFVIGIVLSLAGLFVPIPLMALDLLTGTVQAYIFMVLSMVFIGAAVSGDETSAPRRGQENT
>NC_008784.1|WP_004201694.1|1287163_1287472_+|membrane-protein
MIEMWETARASFDGIAAAIGLALGFAAGACHFVSLGWNSRLFVAGRAGVALALQFARVALAVAVLVVLARAGFGMLVAGSAGFFAARAIAVRRAAALTGARR
>NC_008784.1|WP_004188438.1|1286679_1287171_+|AtpZ/AtpI-family-protein
MMKRRPPEVKREARDDAARGDARHAGAGAAPDDPRGAARRDPSPGSRAARGGATHPAARAAEPAAPKPAADRVERAAHTAAARAARGARDPEPSLGRRLAQIGVLGWTIVAPTLAALALGRWLDRMFATRVFFSAPLLMLGAALGLWLAWRWMKAQQHGDRDD
>NC_008784.1|WP_004188221.1|1286227_1286683_+|F0F1-ATP-synthase-subunit-epsilon
MGAELRVTIATPARVCVDDLPIVSLRAEDASGAFGIRAGHVDFVTLLRASVVRWRTADGATHYAALDGGVLRVTRGARIEIACRDAVLGESLAELEAVVRGVRATQLDEKRRARVDETRLHAQAVRRLLTYLRPEHAKDGVHAPLKPETLE
>NC_008784.1|WP_004188073.1|1284633_1286238_+|F0F1-ATP-synthase-subunit-beta
MADPQATNGTGAVCAERDASDVGDVSDVGDARDEGAGRVVAVRGAVVDVAFDGGALPALNEALTIPVDGAAPILAEVHAHLSDAAVRALALGPTGGLRRGAAVRATGGPIRVPVGDAVLGRLLSVTGAPGDDGAALAADVERRPIHRGAPLLAEQKSANALFATGIKVIDLLAPLAQGGKAAMFGGAGVGKTVFVMELIHAMVERYRGISVFAGIGERSREGHEMLLDMRGSGVLGRTVLVYGQMNEPPGARWRVPLTALAIAEYFRDERAQNVLLLMDNVFRFVQAGAEVSGLLGRLPSRVGYQPTLASEVAALQERIASVEGAAVTAIEAVYVPADDFTDPAVTAIAAHVDSMVVLSRAMAAEGMYPAIDPVASSSILLDPLVVGEAHVEVAIEVRRVIEHYRELQDVIALLGIDELGADDRRLVGRARRLQRFLTQPFAVTEAFTGQAGASVEIADTIAGCRAILRGDCDDWRESSLYMVGTLDDARRKEAAAREADARREAAAAASGAGPGTTSDPASGSAEPQGARHGR
>NC_008784.1|WP_004187423.1|1284404_1284662_-|hypothetical-protein
MPFVACGSATVAPVWLVRRWLHHNGARRPPADLGQETGNRQTKRGIAQSETIDASASGADKVRAASIVDSNQIPQTYAWLQWPCQ
>NC_008784.1|WP_004188840.1|1282479_1284273_-|alpha/beta-fold-hydrolase
MDTRHAPESGAPDAPLPAHPPASYAPESPYRIFDLAKEASVAKLTSGLSPASLQLALADWLIHLAAAPGKRAELATLALRHAALLGQYLLEAATGRTPAAPAQPSPGDRRFRAGAWQLEPYRFWHQSFLLAEQWWRAATRDVPGVSPHHEDVVAFSARQMLDTFAPANYVATNPEIAQRTALTGGANLAQGVWNYLDDVRRLITKQPPAGAEQFELGRNLATTPGRVVFRNHLIELLQYSPTTPDVYAQPVLIVPAWIMKYYILDLSAHNSLIRYLVGEGHTVFCISWRNVDASDRDLSLDDYRKLGVMDALDTIGAIVPGEKIHATGYCLGGTLLSIAAAAMANTGDDRLASITLLAAQTDFAEPGELQLFIDDSEIHFLESMMWERGYLGAHQMAGSFQLLMSNDLIWSRVIHDYLLGERTPMIDLMAWNADSTRMPYRMHSEYLRHLFLDNDLATNRYVIDGQTVSVHNIRAPFFVVGTEHDHIAPWRSVYKIHYLSGSDVTFVLTAGGHNAGIVSEPGHAKRHYRMKMTAAAAPSISPDEWLAGATDFEGSWWPAWHAWLARHSSPQRVAPPPLGKPGAHTLGDAPGTYVFQK
>NC_008784.1|WP_011204278.1|1281065_1282496_-|bifunctional-enoyl-CoA-hydratase/phosphate-acetyltransferase
MCSRNKECRVDREILQNRPFDSLAIGDSASLVRTASRDDIDLFAAMSGDVNPAHLDAAFAAHDLFGHVVVHGMWTGALVSAVLGTKLPGPGTIYLDQTLEFRHPVAPGDTITATVTVAEKRPEKRIVLLDTRCTNQDGHVVLRGTATVIAPDTPITWERVPGPEVAVRRHDRYETFVRDAREQPPLRTAIVHPCSPDALRAAIDARDANLIEPILIGPQAKIRAIADAAGVDLAGVPIEAVEHSHAAAARAVEMGGAGEVAALMKGSLHTDELLAAVIGPASRLRTERRISHVYAMDVPAYPKPLLITDAAINIAPTLEQKRDICQNAVDLLHVLGVERPRVAVLAAVETVNPKMPSTLDAAALTVMAARGQIAGAIVDGPLAFDNAVSAVAAMSKGIASPVAGDADVLLVPDLEAGNMLAKQLMYFAGADAAGLVLGTRLPIILTSRADSLRVRIASAALAKLVAERTRAGALAS
>NC_008784.1|WP_004188458.1|1279890_1281069_-|acetate/propionate-family-kinase
MSEPLLLTFNAGSSTLKIGLYSVANGEPAPLGRGKIDFNRAPLQFEYANGGEAHAVPLAAPVTDDLHAVLDEALGWIDAHLSVHELVSVGHRVVHGGDTFDGPVRIDERTLDAIAALVPLAPLHQPQSVRLIRALRHVRPHLPQVASFDTAFHRTQSDLVRRFALPRALFDAGIKRYGFHGLSYRYVAGRLRERHPSIARGKVVAAHLGSGASLCALDAGVSRDTSMGFSTLDGIPMATRCGALDAGVVLHLQKTLGRTLDDVEQMLYHRSGLLGVSGVSGDARALLADPSAGARDALELFAFRIAGETARLAATLGGLDALVFTAGIGEHQPQTRAAVCERLRWLSVELDAHANARNAETVSRDGSRVAVLVVPTDEEQVIARDAASVLHA
>NC_008784.1|WP_004188355.1|1289164_1291177_+|F0F1-ATP-synthase-subunit-alpha
MTPTPDAPAAADAATGAGWLARRRGALARVALAPIAQAIGRVERVADGIAFVSGLEDTMLNEVLRFEGGVTGFAHTLDEDLISVVLLDPDAGVRAQTAVARTGAVLEVPAGPQLLGRVVDPLGRPLDGGAPLDAAHTLPIERAAPAIIERDLVSEPLDTGVLIVDALFTIGRGQRELIIGDRATGKTSLAIDAIVNQRHSDVICVYVAIGQRASAVRRVIDAVRRYGAPERCVFVVAPAACAPGLQWIAPFAGFSIAEYFRDRGQHALVVVDDLTKHAATHRELALLTREPPGREAYPGDIFYVHARLLERAAKLSAALGGGSLSALPIAETDAGNLAAYIPTNLISITDGQIVLDSALFAANQRPAVDVGLSVSRVGGKAQHPALRAASGRLRLDYAQFLELEAFTRFGGLTDARLRAQITRGERIRALITQPRFRALRTLDEVVLLKALAAGTLDAMSPDLVAPLRERLPAWLDARIAALTPALAPPRDWLADDAALDALAESVGELIERIAADAARRATAGMPAEDAAGDIGGAFGGEQARGDADRDADHGANREVSREVSPEASREVSREVSREVSHEADRDAAADAARVAGRAPGRAEPDRAVPRAMPDGPPRAQADGDRASASRPPPDARGDAARTAPSPQGGADANVNADANVDAEAEARHKR
>NC_008784.1|WP_004188303.1|1291173_1292022_+|F0F1-ATP-synthase-subunit-gamma
MSDKLAAIEARTDTARQLQTVIGAMQGVAAARAHEAQQRLPGIRASAATVGAAIGDALSAGARSGETAAGARAAPRARFVVVLCSEQGFVGAYNAQLIEHATRPGPSVSREYMMVGSRGAMLADAGGVPLVWRTPMAARADDVVHLANRITDALYAHLAKRGAQPVSIVHAMPGGAARLEVTERRLLPFDYARFDTAPRAQPPLVHLPPATLLAELAQAYVFVELCEAAMLAFAAENEARTRAMIAARESVERALGDLLQAYRIARQDEITADIVELAASGL
>NC_008784.1|WP_004198321.1|1292236_1293262_+|alcohol-dehydrogenase-AdhP
MAQYMKAAVVHAFGEPLRIEEVPVPTPGAGQILVNVKASGVCHTDLHAADGDWPVKPTLPFIPGHEGVGFVAAVGEGVRHVKEGDRVGVPWLYTACGHCEYCQTGWETLCHEQQNTGYSVNGSYAEYVLADPNYVGHLPSNVAFDEIAPILCAGVTVYKGIRVTDTRPGQWIAISGIGGLGHVAVQYAKAMGLHVVAVDVAPQKLELARKLGATFVVDASKDDPAAVIQKEIGGVHGVLVTAVSRGAFAQALGMVRRGGTVSLNGLPPGDFPLPIFSTVLNGITVRGSIVGTRRDLQESLDFAAEGLVRAHIHRDKLEHINGVFSALREGKVDGRIVLTGQ
>NC_008784.1|WP_004198322.1|1293338_1293842_+|hypothetical-protein
MRGAGRASPSRARRYENVSKEPNTHREAGAPVHRYRLQVRNMNGECRTYELRLSSLDDGYTLEIDEWLNFPDTHLGDVTPVHVSRPVQFAVPAHEFYRRRRAFRTELIESVAAALRAGEVVRMRDSPDEYPGGHAGNPWVNWIRADLRANPGGRPPPVGDDMQDLIH
>NC_008784.1|WP_004187158.1|1293899_1294409_-|hypothetical-protein
MRRIYFLLPDADTARAIVDELLLKRIEWRHIHVVANDRVPLENLPEASIAQSSDLLPALARGTAADGVTGALAGLAAIAFPPAGLTIAGGAVVAFAIAGAGFGAWVSTMIGVSVPNTRLKHFEDAVDNGELLMMIDVHRDRVEEIEALVKQHHPNAHLEGTDPTIPAFP
>NC_008784.1|WP_044302747.1|1294910_1296515_+|methyl-accepting-chemotaxis-protein
MAPFHRRTTRNARTPTLSFRQKLWLPLVISLIALLLVSISSAWLSYQTRMEERRNDLTNVAHVGLSIVREYAALAQRGVLTDAQARKEALERLRSVRYGSDGYFIVIDSSPRMIMHPIKPDTVGKDLRHVADADGRHHYLTFASVAQSPQGGFVDYVFAHPNAHPAKAVDKLGYVIRYAPWDWIISTGAYIDDIQAAFAKSLCLSAGVFALLAALLALSVVYTNRGIERMIGGDPRIAAHMAGVIASGDLATPFATRREDRSSLMFAISQMRDALANAVAQIRASAGYVATTAGEIADSNMDLSSHTECQATALQQAASSMQRLTERVRDTADRARAASELAGSAARITDRGGDMVVRVVAAMNDIRAESRKMVDIIGVIEGIAFQTNILALNAAVEAARAGNEGRGFAVVASEVRVLAQRSASAAKDIRALIGRAAERVGNGAELVEATGATIGEAQHAICRVTGIVQDIAAAATDQSQGLEQINAAVSQMDSVTRRNATLVEHAAIAAQSLNEQSRCLQDAVAAFRTEALGC
>NC_008784.1|WP_004198323.1|1296606_1296765_-|hypothetical-protein
MRARRSHGAGIRLGFDKPSGTHSSPHDGWVQTDIAMRLPQISLMPDQALANE
>NC_008784.1|WP_004187376.1|1296864_1298700_-|response-regulator
MHVEVFAQHPSCPGWHGEMARRIRAFDWSATELGPLERWPASLVAAVRTVLASPVPLVMLWGASGYMLYNDAYAAFAGGRHPYLLGQPVELGWPEVADFNRNVMRTCLAGGALSYRDKALVLLRNGRPEEVWMDLYYSPLAGDDGAPAGVLAVVVETTERVLAARHRDRAKAALHETNAELRRLTETLEQRVADAITERASIEEQLRQAQKMEAIGSLTGGIAHDFNNVLQVVSSNLQMLSAELGEDARAQRRIASAANAVARGAQLASHLLAFARRQPLAPAVLDPRGLIDGMREMLHRALGESVHVDADLRDDVWNVLADRHQFENALLNLAINARDAMRGEGTLKITACNIVLEAGRHARRNGLPPGEYVAFDIADNGVGMTPDILERVFEPFFTTKPDGQGTGLGLSMVFGFVKQSGGHTSIESAPGRGTTVRLLLPRCREAPAGEPAAQRRLPAEGGRETILVVEDDADVRLAVVDMLAQLGYKVITASDGEAGLLALESGAPIDLLFTDVIMPGRIKGGELARRAAQRVPPVPVLFTSGYTRDEIFHAGRLDPGVMLLGKPYRRDELAHKVRSVLDAHASARRAHGARHAQADPRAKTAAARVQR
>NC_008784.1|WP_004188525.1|1298849_1299974_-|ABC-transporter-permease
MRRLAIIYRLGVKELWSLVRDPILLVLIAYTFTASIYSAATARPDTLHMAPIAIIDEDASPLSARIASAFFPPQFALPRMVTLAEADRGMDAGDFTFALDIPPNFQRDVLAGRPAQIQLNVDATRMSQAFTGNGYVQQIVSGEIDDFARRYRANTAPPVDIAMHMRFNPNLDQTWFGSLMEVINNVTLLSMVLTGAALIREREHGTIEHLLVMPVTPGEIMLAKVWSMGLVVACAAAFSLAFVVRGALHVPIEGSVALFVIGMAIHLFATTSMGIFLATLVRSMPQFGMLLVLVLLPLQLLSGSLTPRESMPFAVQNIMLAAPTTHFVEIGQAILYRGAGIETVWRQFLILAVIGTALFLLSLKRFRKTIGQMA
>NC_008784.1|WP_004188377.1|1299976_1303192_-|ATP-binding-cassette-domain-containing-protein
MSAPSVVRFSDVSLRYGKTVALERITLEIPAGLTIGLIGPDGVGKSSLLALAAGARALQTGAVDALGGDMRSRRHRERVCRRIAYMPQGLGKNLYPTLSVEENLQFFARLFGHDADERRRRIDALTRSTGLFAFLSRPAGKLSGGMKQKLGLCCALIHDPDLLILDEPTTGVDPLARAQFWDLIARIRSERPAMSVIVATAYMDEAQRFDWLIAMDAGRVLATGAPAELLARTGCDSLEAAFIALLPEDERRGHKPVTLEPLRADAQTGTAIEARGLTMRFGDFTAVDHVSFRIRRGEIFGFLGSNGCGKSTTMKMLTGLLPATEGTAQLFGKTVDPKDINTRRRVGYMSQAFSLYSELTVRQNLVLHARLFGVPAAEIDARVDEMARRFGLADIYDMLPDSLPLGMRQRLSLAVAMVHKPELLILDEPTSGVDPVARDSFWQLMIDLARRDRVTIFISTHFMNEAQRCDRISLMHAGRVLASDAPAALVRARGAATLEEAFIGYLVDASAQEAQEAQGGAGERPGAGERAAGESVAGRGAATDGDADGAHARPAAYANGAAQHRAPDADAAGTDVAAETGARDDARTAHAAGHSAGNDVRATVGSEVGSEVASEAGLAASAESGSERGVAHGAERAREPAADAGAAIDVEPGASAESATAAVAPARHAESAATSPRAGNAPAGTPFAAAPAEPPHRAFSAQRALSYMWREMLELRRDPVRATLALIGSLVLMCVIGIGISLDVEDLTYAVLDRDQTELSHDYALNLSGSRYFVERPPIADYAALDRRMRDGELSLAIEIPPNFARDVERGAPAQIGMWIDGAMPQRAETIRGYAIGMHTMWLADKARHRLGVTLAPRAEVVTRYRYNPDVKSLPAMIPAVMPLLLLMLPAMLTALAVVRERELGSILNLYVTPVTRTEFLIGKQVPYVVLAMLNFLLMTMLARIAFDVPVKGSFMTLLLAVLIFNVVATGIGLLASTFTRSQVAAIVMTIIGTMIPTVQFAGLLTPLSSLEGTGRLIGLVYPATYMLSISRGVFNKALSLHELYSQFWPLAACVPVILGATILLLKKQER

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

692935 : 772605

uncultured_Caudovirales_phage(40.0%)

transposase,holin,plate

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_011204354.1\|692935_693886_-\|holin	choline ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_004186852.1\|694153_695098_+	GlxA family transcriptional regulator	NA	NA	NA	NA
WP_004198575.1\|695569_697273_+	peptidase	NA	NA	NA	NA
WP_004200641.1\|697390_698617_+	M20/M25/M40 family metallo-hydrolase	NA	NA	NA	NA
WP_004200640.1\|698671_699814_-	porin	NA	NA	NA	NA
WP_004198249.1\|699922_700045_-	hypothetical protein	NA	NA	NA	NA
WP_073699106.1\|700041_700896_-	glycine/betaine ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_004186939.1\|700931_702485_-\|holin	choline-sulfatase	NA	NA	NA	NA
WP_004186868.1\|702620_703520_+	LysR family transcriptional regulator	NA	NA	NA	NA
WP_004186920.1\|703663_704539_+	formyltetrahydrofolate deformylase	NA	NA	NA	NA
WP_004186811.1\|704625_706281_-	APC family permease	NA	NA	NA	NA
WP_004186918.1\|706461_707325_-	glycine betaine ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_004186910.1\|707434_708580_-	hybrid-cluster NAD(P)-dependent oxidoreductase	NA	NA	NA	NA
WP_004186879.1\|708600_709869_-	aromatic ring-hydroxylating dioxygenase subunit alpha	NA	NA	NA	NA
WP_004186884.1\|709893_710679_-	drug:proton antiporter	NA	NA	NA	NA
WP_004202150.1\|710675_711848_-	electron transfer flavoprotein subunit alpha/FixB family protein	NA	NA	NA	NA
WP_004186901.1\|711852_713778_-	(Fe-S)-binding protein	NA	NA	NA	NA
WP_004186960.1\|713780_715844_-	NADH:flavin oxidoreductase	NA	NA	NA	NA
WP_004186987.1\|715904_716438_-	4-vinyl reductase	NA	NA	NA	NA
WP_004186989.1\|716588_717560_-	membrane dipeptidase	NA	NA	NA	NA
WP_011807509.1\|717632_718907_-	serine hydroxymethyltransferase	A0A219Y950	Aeromonas_phage	1.2e-104	54.1
WP_009923708.1\|718918_719182_-	hypothetical protein	NA	NA	NA	NA
WP_004198247.1\|719340_720366_+	GlxA family transcriptional regulator	NA	NA	NA	NA
WP_004186783.1\|720543_721743_-	formaldehyde dehydrogenase, glutathione-independent	A0A2K9L7I1	Tupanvirus	1.9e-11	26.8
WP_004186794.1\|722182_723199_-	LacI family DNA-binding transcriptional regulator	NA	NA	NA	NA
WP_004546670.1\|723387_724953_+	glycoside hydrolase 68 family protein	NA	NA	NA	NA
WP_004198244.1\|725085_726750_+	glycoside hydrolase family 32 protein	NA	NA	NA	NA
WP_004186853.1\|727319_728573_-	HlyD family efflux transporter periplasmic adaptor subunit	NA	NA	NA	NA
WP_004196352.1\|729053_730649_-	efflux transporter outer membrane subunit	NA	NA	NA	NA
WP_004184586.1\|730645_730828_-	hypothetical protein	NA	NA	NA	NA
WP_004186828.1\|730953_731949_-	glycosyltransferase family 2 protein	NA	NA	NA	NA
WP_004184379.1\|732213_733800_-	DHA2 family efflux MFS transporter permease subunit	NA	NA	NA	NA
WP_004186962.1\|733796_735116_-	glycosyltransferase	NA	NA	NA	NA
WP_004199051.1\|735123_735252_-	hypothetical protein	NA	NA	NA	NA
WP_004186983.1\|735337_736237_-	alpha/beta hydrolase	NA	NA	NA	NA
WP_009923697.1\|736516_736690_+	hypothetical protein	NA	NA	NA	NA
WP_080516849.1\|736787_737159_-	hypothetical protein	NA	NA	NA	NA
WP_004190471.1\|737383_737809_-	hypothetical protein	NA	NA	NA	NA
WP_004190863.1\|737831_738191_-	hypothetical protein	NA	NA	NA	NA
WP_011204346.1\|741745_743461_-	OmpA family protein	NA	NA	NA	NA
WP_004202226.1\|744844_745438_-	hypothetical protein	NA	NA	NA	NA
WP_004190606.1\|745443_745833_-	DUF4150 domain-containing protein	NA	NA	NA	NA
WP_004190800.1\|745875_746592_-	DUF3540 domain-containing protein	NA	NA	NA	NA
WP_004202229.1\|746594_747665_-	pentapeptide repeat-containing protein	NA	NA	NA	NA
WP_004200633.1\|747664_749881_-	DUF2169 domain-containing protein	NA	NA	NA	NA
WP_004190563.1\|749884_752173_-	type VI secretion system tip protein VgrG	A0A2H4JCD4	uncultured_Caudovirales_phage	1.0e-26	24.6
WP_004196185.1\|752338_754585_-	type VI secretion system tip protein VgrG	A0A2H4JCD4	uncultured_Caudovirales_phage	2.1e-24	25.0
WP_004190851.1\|757448_758438_-\|plate	type VI secretion system baseplate subunit TssG	NA	NA	NA	NA
WP_004196180.1\|758434_760297_-\|plate	type VI secretion system baseplate subunit TssF	NA	NA	NA	NA
WP_004190879.1\|760310_760742_-	GPW/gp25 family protein	NA	NA	NA	NA
WP_004196178.1\|760821_761349_-	type VI secretion protein	NA	NA	NA	NA
WP_004530038.1\|761492_763004_-	type VI secretion system contractile sheath large subunit	NA	NA	NA	NA
WP_004202234.1\|763000_763549_-	type VI secretion system contractile sheath small subunit	NA	NA	NA	NA
WP_004188491.1\|763582_764521_-	hypothetical protein	NA	NA	NA	NA
WP_096325460.1\|764643_765764_-\|transposase	IS3 family transposase	S5WIU1	Leptospira_phage	3.6e-49	39.5
WP_011204645.1\|767167_767500_+	hypothetical protein	NA	NA	NA	NA
WP_004188420.1\|767469_768984_-	acetyl-CoA hydrolase/transferase family protein	NA	NA	NA	NA
WP_004188272.1\|769348_770038_+	CDP-alcohol phosphatidyltransferase family protein	NA	NA	NA	NA
WP_004206084.1\|770797_771799_+	HpnL family protein	NA	NA	NA	NA
WP_004188389.1\|771837_772605_+\|holin	phosphocholine cytidylyltransferase family protein	NA	NA	NA	NA

DBSCAN-SWA_2

1550868 : 1597520

Leptospira_phage(33.33%)

transposase,plate

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_004190585.1\|1550868_1552272_+\|plate	type VI secretion system baseplate subunit TssK	NA	NA	NA	NA
WP_004190689.1\|1552287_1553604_+	DotU family type VI secretion system protein	NA	NA	NA	NA
WP_004190681.1\|1553606_1557236_+	type VI secretion system membrane subunit TssM	NA	NA	NA	NA
WP_004190273.1\|1558132_1558360_-	hypothetical protein	NA	NA	NA	NA
WP_011807597.1\|1558358_1560947_+	protein kinase	A7IVH4	Paramecium_bursaria_Chlorella_virus	2.2e-12	24.3
WP_004190988.1\|1560999_1562079_+	type VI secretion system protein TssA	NA	NA	NA	NA
WP_004190671.1\|1562141_1562720_+	type VI secretion system contractile sheath small subunit	NA	NA	NA	NA
WP_004190849.1\|1562712_1564221_+	type VI secretion system contractile sheath large subunit	NA	NA	NA	NA
WP_004190698.1\|1564280_1564772_+	type VI secretion system tube protein Hcp	NA	NA	NA	NA
WP_004196148.1\|1564790_1565351_+\|plate	type VI secretion system baseplate subunit TssE	NA	NA	NA	NA
WP_004190509.1\|1565355_1567227_+\|plate	type VI secretion system baseplate subunit TssF	NA	NA	NA	NA
WP_004190820.1\|1567223_1568702_+\|plate	type VI secretion system baseplate subunit TssG	NA	NA	NA	NA
WP_004190714.1\|1568680_1571335_+	type VI secretion system ATPase TssH	A0A1S6UBG5	Serratia_phage	2.7e-79	30.9
WP_004203275.1\|1571331_1573536_+	type VI secretion system tip protein VgrG	A0A077K8Q4	Ralstonia_phage	9.6e-46	29.9
WP_004196151.1\|1573610_1574264_+	hypothetical protein	NA	NA	NA	NA
WP_011204338.1\|1574223_1575252_+	RHS repeat protein	NA	NA	NA	NA
WP_038802950.1\|1575279_1576400_-\|transposase	IS3 family transposase	S5WIU1	Leptospira_phage	3.6e-49	39.5
WP_004204352.1\|1576695_1576968_+	hypothetical protein	NA	NA	NA	NA
WP_011205668.1\|1576964_1578656_+	ShlB/FhaC/HecB family hemolysin secretion/activation protein	NA	NA	NA	NA
WP_004187717.1\|1578756_1581474_+	filamentous hemagglutinin N-terminal domain-containing protein	A0A0R6PJK4	Moraxella_phage	2.0e-13	25.2
WP_004187807.1\|1581720_1584438_-	aconitate hydratase AcnA	NA	NA	NA	NA
WP_004188028.1\|1584485_1585937_-	bifunctional 2-methylcitrate dehydratase/aconitate hydratase	NA	NA	NA	NA
WP_004188791.1\|1586013_1586523_-	hypothetical protein	NA	NA	NA	NA
WP_004188261.1\|1586679_1587699_-	lyase	NA	NA	NA	NA
WP_004187735.1\|1587896_1588880_-	malate dehydrogenase	NA	NA	NA	NA
WP_004188685.1\|1589178_1589979_+	GntR family transcriptional regulator	NA	NA	NA	NA
WP_004536542.1\|1590178_1590595_+	succinate dehydrogenase, cytochrome b556 subunit	NA	NA	NA	NA
WP_004187439.1\|1590599_1590968_+	succinate dehydrogenase, hydrophobic membrane anchor protein	NA	NA	NA	NA
WP_004188402.1\|1590972_1592748_+	succinate dehydrogenase flavoprotein subunit	NA	NA	NA	NA
WP_004187935.1\|1592769_1593471_+	succinate dehydrogenase iron-sulfur subunit	NA	NA	NA	NA
WP_004188825.1\|1593472_1593745_+	succinate dehydrogenase assembly factor 2	NA	NA	NA	NA
WP_004188362.1\|1593797_1595099_+	citrate (Si)-synthase	NA	NA	NA	NA
WP_004187842.1\|1595195_1596170_-	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_004200651.1\|1596245_1596389_+	hypothetical protein	NA	NA	NA	NA
WP_038802950.1\|1596399_1597520_-\|transposase	IS3 family transposase	S5WIU1	Leptospira_phage	3.6e-49	39.5

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. NC_008785

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CRISPR-Cas detection and classification

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection

2. NC_008784

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CRISPR-Cas detection and classification

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection