CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Prophage number	Anti-CRISPR protein number
NC_008760	Polaromonas naphthalenivorans CJ2 plasmid pPNAP04, complete sequence	0 crisprs	NA	2	0
NC_008764	Polaromonas naphthalenivorans CJ2 plasmid pPNAP08, complete sequence	0 crisprs	NA	0	0
NC_008758	Polaromonas naphthalenivorans CJ2 plasmid pPNAP02, complete sequence	0 crisprs	DinG	0	1
NC_008763	Polaromonas naphthalenivorans CJ2 plasmid pPNAP07, complete sequence	0 crisprs	NA	0	0
NC_008759	Polaromonas naphthalenivorans CJ2 plasmid pPNAP03, complete sequence	0 crisprs	NA	0	0
NC_008757	Polaromonas naphthalenivorans CJ2 plasmid pPNAP01, complete sequence	0 crisprs	cas3	17	0
NC_008761	Polaromonas naphthalenivorans CJ2 plasmid pPNAP05, complete sequence	0 crisprs	PD-DExK	0	0
NC_008781	Polaromonas naphthalenivorans CJ2, complete genome	3 crisprs	c2c9_V-U4,RT,DEDDh,DinG,PD-DExK,WYL,c2c10_CAS-V-U3,cas3,csa3,cas14j	7	0
NC_008762	Polaromonas naphthalenivorans CJ2 plasmid pPNAP06, complete sequence	0 crisprs	NA	2	0

Results visualization

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CRISPR-Cas detection and classification

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

17514 : 61523

Acinetobacter_phage(23.08%)

protease,transposase,integrase

attL 25042:25057|attR 50737:50752

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_083758109.1\|17514_17736_+\|transposase	transposase	NA	NA	NA	NA
WP_157040544.1\|17674_17953_+	hypothetical protein	NA	NA	NA	NA
WP_076611837.1\|18005_19049_-\|transposase	IS701-like element ISPna6 family transposase	NA	NA	NA	NA
WP_157040545.1\|19362_19512_-	hypothetical protein	NA	NA	NA	NA
WP_011798423.1\|19861_20719_+	carboxylating nicotinate-nucleotide diphosphorylase	NA	NA	NA	NA
WP_011798424.1\|20813_21116_+	type II toxin-antitoxin system MqsR family toxin	NA	NA	NA	NA
WP_011798425.1\|21118_21520_+	type II toxin-antitoxin system MqsA family antitoxin	NA	NA	NA	NA
WP_157040546.1\|22594_22801_+	hypothetical protein	NA	NA	NA	NA
25042:25057	attL	NA	NA	NA	NA
WP_157040547.1\|25475_27167_-	hypothetical protein	NA	NA	NA	NA
WP_041376462.1\|27457_27769_-	hypothetical protein	NA	NA	NA	NA
WP_011798428.1\|27966_30036_+	serine recombinase	A0A1B2LRQ3	Wolbachia_phage	4.0e-09	26.5
WP_157040557.1\|30048_31449_-\|transposase	IS66 family transposase	A0A218MNE7	uncultured_virus	2.6e-73	39.3
WP_157040548.1\|33333_34608_-	tellurium resistance protein	A0A160DF64	Gordonia_phage	8.1e-21	29.6
WP_011798434.1\|35588_35774_-	hypothetical protein	NA	NA	NA	NA
WP_011798435.1\|35809_37090_+\|transposase	IS5-like element ISPna3 family transposase	K4ICS3	Acidithiobacillus_phage	1.3e-58	45.2
WP_086000582.1\|37862_38147_-\|integrase,transposase	DDE-type integrase/transposase/recombinase	S5WIU1	Leptospira_phage	1.2e-12	39.8
WP_041377766.1\|38841_39069_-	hypothetical protein	NA	NA	NA	NA
WP_011798440.1\|39298_40243_+	hypothetical protein	NA	NA	NA	NA
WP_041377801.1\|40482_41526_+	DUF475 domain-containing protein	A0A172Q0Y5	Acinetobacter_phage	1.6e-83	51.0
WP_011798442.1\|41567_42146_+	TerD family protein	K4JRX3	Caulobacter_phage	1.4e-28	37.7
WP_011798443.1\|42182_42758_+	TerD family protein	K4JRX3	Caulobacter_phage	1.1e-33	41.3
WP_011798444.1\|43354_43936_+	TerD family protein	A0A2P1N0C0	Streptomyces_phage	2.9e-10	29.6
WP_011798445.1\|43943_44963_+	ATP-grasp domain-containing protein	NA	NA	NA	NA
WP_011798446.1\|45016_46171_+	hypothetical protein	NA	NA	NA	NA
WP_011798447.1\|46148_46904_+	hypothetical protein	A0A172Q0Q4	Acinetobacter_phage	2.9e-18	29.0
WP_011798448.1\|46900_47992_+\|protease	cysteine protease StiP family protein	A0A172Q0S8	Acinetobacter_phage	1.2e-36	32.1
WP_011798449.1\|47984_48932_+	HpcH/HpaI aldolase/citrate lyase family protein	NA	NA	NA	NA
WP_041377768.1\|48934_50191_+	tellurium resistance protein	NA	NA	NA	NA
WP_011798451.1\|50201_51701_-	kinase	NA	NA	NA	NA
50737:50752	attR	NA	NA	NA	NA
WP_157040558.1\|51797_53387_-	protein phosphatase 2C domain-containing protein	NA	NA	NA	NA
WP_011798453.1\|53530_54583_-	VWA domain-containing protein	NA	NA	NA	NA
WP_011798454.1\|54667_55309_-	VWA domain-containing protein	NA	NA	NA	NA
WP_011798455.1\|55315_55957_-	TerD family protein	A0A2P1N0C0	Streptomyces_phage	9.1e-05	32.8
WP_011798456.1\|55969_56608_-	VWA domain-containing protein	NA	NA	NA	NA
WP_011798457.1\|56854_57163_-	hypothetical protein	NA	NA	NA	NA
WP_011798458.1\|57274_57910_-	hypothetical protein	NA	NA	NA	NA
WP_011798459.1\|57906_58269_-	DUF4810 domain-containing protein	NA	NA	NA	NA
WP_011798460.1\|58279_58612_-	hypothetical protein	NA	NA	NA	NA
WP_011798461.1\|58611_59625_-	curli production assembly protein CsgG	NA	NA	NA	NA
WP_049763843.1\|59743_60301_-	hypothetical protein	NA	NA	NA	NA
WP_011798463.1\|60389_60749_+	hypothetical protein	NA	NA	NA	NA
WP_157040549.1\|60763_61261_-\|transposase	IS5 family transposase	A0A0N9SJT9	Paenibacillus_phage	2.9e-19	37.5
WP_157040550.1\|61262_61523_-\|transposase	transposase	NA	NA	NA	NA

DBSCAN-SWA_2

67548 : 117326

Wolbachia_phage(25.0%)

tail,integrase,transposase

attL 70955:70972|attR 108189:108206

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_157040553.1\|67548_68133_-\|integrase	integrase, catalytic region	NA	NA	NA	NA
WP_049763846.1\|68145_69357_-\|transposase	transposase	NA	NA	NA	NA
WP_011798475.1\|69632_70439_+	hypothetical protein	NA	NA	NA	NA
WP_011798476.1\|70525_70747_-	YdcH family protein	NA	NA	NA	NA
70955:70972	attL	NA	NA	NA	NA
WP_011798477.1\|71221_73051_+\|integrase	tyrosine-type recombinase/integrase	A0A2D1G8E2	Mycobacterium_phage	1.0e-08	31.1
WP_049763847.1\|73474_74461_-	ParB/RepB/Spo0J family partition protein	NA	NA	NA	NA
WP_011798479.1\|74463_75657_-	AAA family ATPase	A0A240F4U1	Ochrobactrum_phage	3.4e-29	29.2
WP_041377775.1\|76188_77499_+	replication initiation protein	NA	NA	NA	NA
WP_041377776.1\|77990_78278_-	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_041377777.1\|78688_79819_+	MBL fold metallo-hydrolase	NA	NA	NA	NA
WP_157040554.1\|80285_80435_+	hypothetical protein	NA	NA	NA	NA
WP_011798484.1\|80431_81538_+	ParB/RepB/Spo0J family partition protein	S5VTK0	Leptospira_phage	4.0e-08	29.1
WP_157040555.1\|81786_81954_-	hypothetical protein	NA	NA	NA	NA
WP_011798485.1\|83263_84334_+	3-deoxy-7-phosphoheptulonate synthase	S4W5F1	Pandoravirus	8.2e-83	48.5
WP_157040560.1\|84338_84533_+	hypothetical protein	NA	NA	NA	NA
WP_041376462.1\|84752_85064_-	hypothetical protein	NA	NA	NA	NA
WP_011798428.1\|85261_87331_+	serine recombinase	A0A1B2LRQ3	Wolbachia_phage	4.0e-09	26.5
WP_011798486.1\|87343_88750_-\|transposase	IS66 family transposase	A0A218MNE7	uncultured_virus	2.6e-73	39.3
WP_011798487.1\|88832_89174_-	IS66 family insertion sequence element accessory protein TnpB	NA	NA	NA	NA
WP_041377779.1\|89170_89530_-\|transposase	transposase	NA	NA	NA	NA
WP_011798489.1\|89633_89930_+	IS66 family insertion sequence element accessory protein TnpB	NA	NA	NA	NA
WP_011798491.1\|91670_92828_+	hypothetical protein	NA	NA	NA	NA
WP_011798492.1\|92960_93977_+\|transposase	IS110 family transposase	NA	NA	NA	NA
WP_011798493.1\|94694_95765_-\|transposase	IS110 family transposase	NA	NA	NA	NA
WP_041377781.1\|97344_98019_+	hypothetical protein	NA	NA	NA	NA
WP_011798495.1\|98165_98402_+	H-NS histone family protein	NA	NA	NA	NA
WP_011798496.1\|98741_99356_-	DUF1326 domain-containing protein	NA	NA	NA	NA
WP_011798497.1\|99488_100283_+	DUF2182 domain-containing protein	NA	NA	NA	NA
WP_011798498.1\|100461_100899_-	universal stress protein	NA	NA	NA	NA
WP_011798500.1\|101361_101760_+	hypothetical protein	NA	NA	NA	NA
WP_157040556.1\|102025_102193_-	hypothetical protein	NA	NA	NA	NA
WP_011798501.1\|102527_104099_-	FAD-dependent oxidoreductase	NA	NA	NA	NA
WP_011798502.1\|104434_104677_-\|tail	phage tail protein	A0A218M5J9	Arthrobacter_phage	3.9e-09	52.6
WP_086000545.1\|105301_106434_-\|transposase	IS630 family transposase	NA	NA	NA	NA
WP_049763850.1\|106722_107763_+	hypothetical protein	NA	NA	NA	NA
WP_041377783.1\|107897_108092_+	hypothetical protein	NA	NA	NA	NA
WP_011798507.1\|108200_108569_+	calcium-binding protein	NA	NA	NA	NA
108189:108206	attR	NA	NA	NA	NA
WP_011798508.1\|108969_109374_+	nuclear transport factor 2 family protein	NA	NA	NA	NA
WP_011798278.1\|109714_111052_-\|transposase	IS4 family transposase	Q9JMP3	Wolbachia_phage	1.8e-55	29.8
WP_011798509.1\|111603_111969_+	H-NS histone family protein	NA	NA	NA	NA
WP_011798510.1\|112856_113309_+	RNA-binding protein	NA	NA	NA	NA
WP_011798511.1\|113642_114518_+	glutathione-dependent disulfide-bond oxidoreductase	NA	NA	NA	NA
WP_011798512.1\|114573_115206_+	glutathione S-transferase	NA	NA	NA	NA
WP_157040256.1\|115958_117326_-\|transposase	ISNCY family transposase	NA	NA	NA	NA

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

2. NC_008757

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

0 : 3492

Klebsiella_phage(33.33%)

transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_011797793.1\|482_1040_-	recombinase family protein	A0A286S1P7	Klebsiella_phage	7.0e-54	58.8
WP_011797795.1\|1476_2436_-\|transposase	IS5-like element ISPna4 family transposase	Q1MVF0	Enterobacteria_phage	6.0e-61	42.8
WP_011797796.1\|2736_3492_-	metallophosphoesterase	A0A2H4J0P0	uncultured_Caudovirales_phage	3.1e-52	45.3

DBSCAN-SWA_2

8207 : 8825

uncultured_Caudovirales_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_041377518.1\|8207_8825_+	hypothetical protein	A0A2H4JFQ3	uncultured_Caudovirales_phage	2.8e-27	34.1

DBSCAN-SWA_3

14027 : 22142

Brucella_phage(20.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_011494290.1\|14027_14369_+	type II toxin-antitoxin system RelE/ParE family toxin	A0A141GEX6	Brucella_phage	2.7e-16	50.0
WP_011494291.1\|14358_14679_+	addiction module antidote protein	NA	NA	NA	NA
WP_139174265.1\|14749_14908_-	hypothetical protein	NA	NA	NA	NA
WP_011797806.1\|15182_15839_-	OmpW family protein	NA	NA	NA	NA
WP_011797807.1\|15985_16846_-	2-hydroxy-6-oxo-6-phenylhexa-2,4-dienoate hydrolase	A0A286MQ79	Mycobacterium_phage	3.2e-05	30.1
WP_011797808.1\|16916_17957_-	4-hydroxy-2-oxovalerate aldolase	E5EQ69	Micromonas_sp._RCC1109_virus	1.5e-44	35.4
WP_011797809.1\|17974_18889_-	acetaldehyde dehydrogenase (acetylating)	G8DDL4	Micromonas_pusilla_virus	1.9e-35	36.4
WP_011797810.1\|18909_19692_-	2-oxopent-4-enoate hydratase	NA	NA	NA	NA
WP_011797811.1\|19779_20391_-	glutathione transferase GstA	NA	NA	NA	NA
WP_011797812.1\|20422_21301_-	biphenyl-2,3-diol 1,2-dioxygenase	NA	NA	NA	NA
WP_011797813.1\|21311_22142_-	cis-2,3-dihydrobiphenyl-2,3-diol dehydrogenase	F2NZ40	Diadromus_pulchellus_ascovirus	1.9e-07	27.0

DBSCAN-SWA_4

28649 : 39289

Yersinia_phage(25.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_011797822.1\|28649_29477_+	DUF945 domain-containing protein	A0A2C9CYF8	Yersinia_phage	6.2e-46	39.8
WP_011797823.1\|30594_31101_+	DNA repair protein RadC	NA	NA	NA	NA
WP_011797824.1\|31718_33758_+	ParB/RepB/Spo0J family partition protein	G8DH78	Emiliania_huxleyi_virus	1.3e-23	27.6
WP_011797825.1\|34522_34831_+	DUF736 domain-containing protein	NA	NA	NA	NA
WP_011797826.1\|34877_35174_-	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_011797827.1\|35616_35967_+	DUF2958 domain-containing protein	A0A1W6DX76	Sphingobium_phage	9.6e-25	54.1
WP_011797828.1\|36328_37126_+	DUF2285 domain-containing protein	NA	NA	NA	NA
WP_011797829.1\|37210_37513_+	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_011797830.1\|37548_38400_+	replication initiator protein A	NA	NA	NA	NA
WP_011797831.1\|38650_39289_+	AAA family ATPase	A0A2H4JGZ2	uncultured_Caudovirales_phage	1.2e-33	40.5

DBSCAN-SWA_5

46176 : 56727

Ostreococcus_tauri_virus(33.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_007182750.1\|46176_47925_+	ubiquinone biosynthesis protein UbiB	A9YVW0	Ostreococcus_tauri_virus	4.5e-38	27.4
WP_007182749.1\|47921_50582_+	UDP-N-acetylglucosamine--LPS N-acetylglucosamine transferase	NA	NA	NA	NA
WP_007182748.1\|50578_51550_+	patatin	A0A1X7QFZ0	Faustovirus	1.2e-05	27.2
WP_007182747.1\|51542_52352_+	hypothetical protein	NA	NA	NA	NA
WP_011797838.1\|52348_53449_+	efflux RND transporter periplasmic adaptor subunit	NA	NA	NA	NA
WP_011797839.1\|53445_56727_+	efflux RND transporter permease subunit	S5VTK5	Leptospira_phage	4.3e-50	22.0

DBSCAN-SWA_6

61876 : 65158

Catovirus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_011797843.1\|61876_63517_+	FAD-binding protein	A0A1V0S9M4	Catovirus	1.5e-48	28.7
WP_011797844.1\|63520_65158_+	long-chain fatty acid--CoA ligase	A0A1V0SBX8	Catovirus	5.2e-12	23.7

DBSCAN-SWA_7

113837 : 115505

Pseudomonas_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_011797897.1\|113837_115505_-	AAA family ATPase	A0A0K0LA94	Pseudomonas_phage	1.2e-43	33.3

DBSCAN-SWA_8

122118 : 199906

Acidithiobacillus_phage(14.29%)

transposase,integrase

attL 116794:116813|attR 192458:192477

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
116794:116813	attL	NA	NA	NA	NA
WP_011797904.1\|122118_122787_-	AAA family ATPase	A0A222YXS3	Escherichia_phage	1.3e-17	32.1
WP_157040459.1\|123119_123305_-\|transposase	transposase	NA	NA	NA	NA
WP_049763799.1\|123238_123613_-\|transposase	IS5/IS1182 family transposase	NA	NA	NA	NA
WP_011797906.1\|123667_123868_-\|transposase	IS5 family transposase	A0A0N9SHJ4	Paenibacillus_phage	2.9e-10	44.6
WP_011797907.1\|124071_125946_-\|integrase	tyrosine-type recombinase/integrase	A0A2D1G8E2	Mycobacterium_phage	1.1e-05	25.9
WP_011797908.1\|126242_126839_-	hypothetical protein	S5WA20	Leptospira_phage	7.7e-06	32.0
WP_011797909.1\|126974_128513_+	sigma-54-dependent Fis family transcriptional regulator	NA	NA	NA	NA
WP_011797910.1\|128724_129060_+	DUF4258 domain-containing protein	NA	NA	NA	NA
WP_011797911.1\|129167_129890_+	VWA domain-containing protein	NA	NA	NA	NA
WP_157040460.1\|129890_130607_+	SpoIIE family protein phosphatase	NA	NA	NA	NA
WP_011797913.1\|130613_132041_+	protein kinase	NA	NA	NA	NA
WP_157040461.1\|131901_135375_+	AAA family ATPase	NA	NA	NA	NA
WP_011797915.1\|135361_136801_+	hypothetical protein	NA	NA	NA	NA
WP_157040462.1\|136825_139267_+	AAA domain-containing protein	NA	NA	NA	NA
WP_011797917.1\|139263_141159_+	hypothetical protein	NA	NA	NA	NA
WP_011797918.1\|141165_143667_-	hypothetical protein	NA	NA	NA	NA
WP_011797919.1\|143663_145226_-	hypothetical protein	NA	NA	NA	NA
WP_011797920.1\|145573_149353_-	helicase SNF2	A0A1B1ISM1	uncultured_Mediterranean_phage	2.7e-24	26.9
WP_041377541.1\|149349_151170_-	hypothetical protein	NA	NA	NA	NA
WP_011797922.1\|151157_151865_-	OmpA family protein	NA	NA	NA	NA
WP_011797923.1\|151861_154312_-	anti-phage defense ZorAB system ZorA	NA	NA	NA	NA
WP_041377542.1\|154416_154617_-	hypothetical protein	NA	NA	NA	NA
WP_011797925.1\|156790_158065_-	SH3 domain-containing protein	NA	NA	NA	NA
WP_157040486.1\|158351_158705_+	hypothetical protein	NA	NA	NA	NA
WP_011797927.1\|158707_161203_+	Hsp70 family protein	A0A0N9QXN8	Chrysochromulina_ericina_virus	7.6e-31	28.8
WP_011797928.1\|161206_162655_+	AAA family ATPase	A0A0K1L651	Scale_drop_disease_virus	3.0e-11	28.0
WP_011797929.1\|162713_164369_+	hypothetical protein	NA	NA	NA	NA
WP_157040463.1\|164825_166365_-\|transposase	IS3 family transposase	A0A1B1P773	Bacillus_phage	1.9e-48	37.0
WP_157040464.1\|166413_166719_-	hypothetical protein	NA	NA	NA	NA
WP_011797930.1\|166678_168343_-	ATP-dependent helicase	A0A1V0SAV1	Catovirus	8.1e-13	23.9
WP_011797931.1\|168339_170277_-	AAA family ATPase	NA	NA	NA	NA
WP_011797932.1\|170792_172820_-	DEAD/DEAH box helicase	NA	NA	NA	NA
WP_011797933.1\|172816_174127_-	BREX system ATP-binding protein BrxD	NA	NA	NA	NA
WP_011797934.1\|174123_176850_-	BREX-2 system phosphatase PglZ	NA	NA	NA	NA
WP_083758101.1\|177214_177289_-	hypothetical protein	NA	NA	NA	NA
WP_011797936.1\|180692_181241_-	hypothetical protein	NA	NA	NA	NA
WP_157040465.1\|181244_182441_-	AAA family ATPase	NA	NA	NA	NA
WP_011797938.1\|182343_186045_-	BREX-2 system adenine-specific DNA-methyltransferase PglX	NA	NA	NA	NA
WP_011797939.1\|186127_187297_-	ATPase	NA	NA	NA	NA
WP_011797940.1\|187487_191771_-	BREX system serine/threonine kinase PglW	A0A2H4UVE2	Bodo_saltans_virus	9.4e-05	23.7
WP_011797941.1\|191767_191989_-	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_011797943.1\|193001_193505_+	hypothetical protein	NA	NA	NA	NA
192458:192477	attR	NA	NA	NA	NA
WP_011797944.1\|193642_194374_-	ATP-binding protein	K4HZD4	Acidithiobacillus_phage	1.0e-76	60.7
WP_011797945.1\|194415_195954_-\|transposase	IS21 family transposase	K4I413	Acidithiobacillus_phage	4.8e-161	57.4
WP_041377544.1\|196613_197126_+	DUF2591 domain-containing protein	F8TVJ2	EBPR_siphovirus	2.1e-12	37.5
WP_011797947.1\|197438_197918_+	hypothetical protein	NA	NA	NA	NA
WP_011797948.1\|198154_199906_+	PRTRC system ParB family protein	I3NLC2	Bifidobacterium_phage	2.6e-09	30.2

DBSCAN-SWA_9

206035 : 213877

Agrobacterium_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_011797956.1\|206035_210985_+	N-6 DNA methylase	A0A223W0B5	Agrobacterium_phage	4.6e-221	33.1
WP_011797957.1\|211148_211691_+	YcbK family protein	NA	NA	NA	NA
WP_041377550.1\|212203_212485_+	hypothetical protein	NA	NA	NA	NA
WP_011797959.1\|212962_213877_+	DUF932 domain-containing protein	A0A0H4INH5	Stenotrophomonas_phage	5.6e-48	37.5

DBSCAN-SWA_10

222674 : 234824

Bacillus_virus(25.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_011797970.1\|222674_224534_+	ATP-dependent helicase	G3MA40	Bacillus_virus	2.2e-27	25.1
WP_157040468.1\|224589_225219_-	hypothetical protein	NA	NA	NA	NA
WP_011797972.1\|226288_227317_+	hypothetical protein	R4JDJ1	Burkholderia_phage	1.8e-26	32.3
WP_011797973.1\|227440_228844_+	DNA repair exonuclease-like protein	NA	NA	NA	NA
WP_157040469.1\|228994_229213_+	hypothetical protein	NA	NA	NA	NA
WP_011797974.1\|229163_229517_-	hypothetical protein	NA	NA	NA	NA
WP_011797975.1\|229819_232252_+	DNA repair ATPase	Q6NDW9	Leptospira_phage	4.1e-21	34.1
WP_011797976.1\|232374_232953_+	hypothetical protein	NA	NA	NA	NA
WP_011797977.1\|233189_234113_+	hypothetical protein	NA	NA	NA	NA
WP_011797978.1\|234179_234824_+	single-stranded DNA-binding protein	A0A0A0P1Q9	Enterobacteria_phage	4.8e-38	63.6

DBSCAN-SWA_11

242314 : 246882

Clostridium_botulinum_C_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_011797986.1\|242314_243709_+	HNH endonuclease	Q331Y3	Clostridium_botulinum_C_phage	8.8e-37	32.4
WP_011797987.1\|243708_244344_+	DUF4400 domain-containing protein	NA	NA	NA	NA
WP_011797988.1\|244509_245103_+	prepilin-type N-terminal cleavage/methylation domain-containing protein	NA	NA	NA	NA
WP_011797989.1\|245523_246882_+	HNH endonuclease	Q331Y3	Clostridium_botulinum_C_phage	1.6e-35	32.5

DBSCAN-SWA_12

261130 : 262006

Escherichia_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_011798005.1\|261130_262006_+	AntA/AntB antirepressor domain-containing protein	A0A0P0ZG08	Escherichia_phage	4.3e-21	48.2

DBSCAN-SWA_13

277323 : 277674

Cronobacter_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_049763812.1\|277323_277674_-	DUF4113 domain-containing protein	F1C5A5	Cronobacter_phage	1.9e-09	38.9

DBSCAN-SWA_14

289002 : 296014

Enterobacteria_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_157040487.1\|289002_289566_+	DNA/RNA non-specific endonuclease	H6X497	Enterobacteria_phage	6.7e-12	36.0
WP_011798032.1\|289578_289833_+	hypothetical protein	NA	NA	NA	NA
WP_011798033.1\|290218_291574_+	hypothetical protein	NA	NA	NA	NA
WP_011798034.1\|291752_292514_+	DUF1837 domain-containing protein	NA	NA	NA	NA
WP_011798035.1\|292513_296014_+	DEAD/DEAH box helicase	F2Y0S4	Organic_Lake_phycodnavirus	3.0e-09	22.5

DBSCAN-SWA_15

314013 : 316325

Acidithiobacillus_phage(100.0%)

transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_011797945.1\|314013_315552_+\|transposase	IS21 family transposase	K4I413	Acidithiobacillus_phage	4.8e-161	57.4
WP_011797944.1\|315593_316325_+	ATP-binding protein	K4HZD4	Acidithiobacillus_phage	1.0e-76	60.7

DBSCAN-SWA_16

323213 : 325935

Clostridium_botulinum_C_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_011798054.1\|323213_324647_-	HNH endonuclease	Q331Y3	Clostridium_botulinum_C_phage	3.8e-35	32.0
WP_041377585.1\|324970_325174_-	hypothetical protein	NA	NA	NA	NA
WP_011798055.1\|325224_325935_-	hypothetical protein	Q6JIG5	Burkholderia_virus	1.4e-22	41.8

DBSCAN-SWA_17

341957 : 344595

Leptospira_phage(50.0%)

transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_157040484.1\|341957_343022_-	hypothetical protein	S5WA20	Leptospira_phage	4.2e-31	32.6
WP_011798081.1\|343021_343594_-	hypothetical protein	NA	NA	NA	NA
WP_011798082.1\|343635_344595_-\|transposase	IS5-like element ISPna5 family transposase	Q1MVF0	Enterobacteria_phage	6.9e-57	41.5

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

3. NC_008758

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region	Region Position	Protein_number	Hit_taxonomy	Key_proteins	Att_site	Prophage annotation

Anti-CRISPR protein detection

Acr_ID: NC_008758.1|WP_011798230.1|19311_19848_+|hypothetical-protein

Click the colored protein region to show detailed information

Acr ID

Acr position

Acr size

Homology with known anti

Neighbor HTH/AcRanker

Neighbor Aca

In prophage

Protospacer in prophage

NC_008758.1|WP_011798230.1|19311_19848_+|hypothetical-protein

19311_19848_+

178 aa aa

hit_Aca_id	identity	query_coverage	hit_coverage
gnl\|BL_ORD_ID\|78	0.4552238805970149	0.7415730337078652	0.7987421383647799

4. NC_008781

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Crispr_ID: NC_008781_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_008781_1

2173541-2173653

Orphan

Consensus_repeat	Method
ACGGATTAAGAGTCCGCTGCTCTACCA	CRISPRCasFinder

1 spacers

The CRISPR arrays of NC_008781_1

>merge|NC_008781|1|2173541-2173653|CRISPRCasFinder
ACGGATTAAGAGTCCGCTGCTCTACCAGCTGAGCTAAGAACCCAAATAAAATTTGGTGGGACGTGCGGGGGTCGAACCCACGACAAACGGATTAAAAGTCCGCTGCTCTACCA

>NC_008781|1|1|2173541-2173653|CRISPRCasFinder
ACGGATTAAGAGTCCGCTGCTCTACCA	GCTGAGCTAAGAACCCAAATAAAATTTGGTGGGACGTGCGGGGGTCGAACCCACGACAA
ACGGATTAAAAGTCCGCTGCTCTACCA

Protein	Signature genes	Signature genes Name	Protein_function
NC_008781.1\|WP_011801437.1\|2174665_2175427_-\|tol-pal-system-protein-YbgF	unknown	unknown	gnl\|CDD\|188247
NC_008781.1\|WP_011801430.1\|2166733_2167804_+\|molybdenum-ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|131197
NC_008781.1\|WP_011801438.1\|2175442_2175982_-\|peptidoglycan-associated-lipoprotein-Pal	unknown	unknown	gnl\|CDD\|274307
NC_008781.1\|WP_011801434.1\|2171387_2171699_-\|Rieske-2Fe-2S-domain-containing-protein	unknown	unknown	gnl\|CDD\|239556
NC_008781.1\|WP_011801443.1\|2180350_2182132_+\|lipid-A-export-permease/ATP-binding-protein-MsbA	unknown	unknown	gnl\|CDD\|131258
NC_008781.1\|WP_157040398.1\|2179163_2180354_+\|O-antigen-ligase-domain-containing-protein	unknown	unknown	gnl\|CDD\|377422
NC_008781.1\|WP_011801440.1\|2177330_2178173_-\|glycosyltransferase-family-2-protein	unknown	unknown	gnl\|CDD\|133042
NC_008781.1\|WP_011801428.1\|2165126_2165966_+\|ModD-protein	unknown	unknown	gnl\|CDD\|238807
NC_008781.1\|WP_011801432.1\|2168975_2170808_-\|thioredoxin-domain-containing-protein	unknown	unknown	gnl\|CDD\|224250
NC_008781.1\|WP_011801441.1\|2178172_2178940_-\|glycosyltransferase-family-2-protein	unknown	unknown	gnl\|CDD\|133005
NC_008781.1\|WP_157040258.1\|2183113_2183254_+\|hypothetical-protein	unknown	unknown	unknown
NC_008781.1\|WP_041377165.1\|2164721_2165108_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|238431
NC_008781.1\|WP_011801439.1\|2176026_2177316_-\|Tol-Pal-system-protein-TolB	unknown	unknown	gnl\|CDD\|235083
NC_008781.1\|WP_086000566.1\|2173748_2174564_-\|tRNA-threonylcarbamoyladenosine-dehydratase	unknown	unknown	gnl\|CDD\|224100
NC_008781.1\|WP_083758034.1\|2168411_2168954_-\|DUF2845-domain-containing-protein	unknown	unknown	gnl\|CDD\|371338
NC_008781.1\|WP_011801431.1\|2167903_2168503_-\|pyridoxamine-5'-phosphate-oxidase	unknown	unknown	gnl\|CDD\|200361
NC_008781.1\|WP_011801433.1\|2171047_2171296_-\|DUF3297-family-protein	unknown	unknown	gnl\|CDD\|371696
NC_008781.1\|WP_011801435.1\|2171718_2173296_-\|DUF2779-domain-containing-protein	unknown	unknown	gnl\|CDD\|371365
NC_008781.1\|WP_011801429.1\|2166051_2166732_+\|molybdate-ABC-transporter-permease-subunit	unknown	unknown	gnl\|CDD\|226629
NC_008781.1\|WP_157040257.1\|2182133_2182781_-\|DUF2726-domain-containing-protein	unknown	unknown	gnl\|CDD\|371282

Protein	Function_ID	Function_description	E-value
NC_008781.1\|WP_011801437.1\|2174665_2175427_-\|tol-pal-system-protein-YbgF	gnl\|CDD\|188247	TIGR02795, Uncharacterized_protein_in_oprL_3'region, tol-pal system protein YbgF. Members of this protein family are the product of one of seven genes regularly clustered in operons to encode the proteins of the tol-pal system, which is critical for maintaining the integrity of the bacterial outer membrane. The gene for this periplasmic protein has been designated orf2 and ybgF. All members of the seed alignment were from unique tol-pal gene regions from completed bacterial genomes. The architecture of this protein is a signal sequence, a low-complexity region usually rich in Asn and Gln, a well-conserved region with tandem repeats that resemble the tetratricopeptide (TPR) repeat, involved in protein-protein interaction.	1.23158e-32
NC_008781.1\|WP_011801430.1\|2166733_2167804_+\|molybdenum-ABC-transporter-ATP-binding-protein	gnl\|CDD\|131197	TIGR02142, Molybdenum_import_ATP-binding_protein_ModC, molybdenum ABC transporter, ATP-binding protein. This model represents the ATP-binding cassette (ABC) protein of the three subunit molybdate ABC transporter. The three proteins of this complex are homologous to proteins of the sulfate ABC transporter. Molybdenum may be used in nitrogenases of nitrogen-fixing bacteria and in molybdopterin cofactors. In some cases, molybdate may be transported by a sulfate transporter rather than by a specific molybdate transporter. [Transport and binding proteins, Anions].	2.49483e-143
NC_008781.1\|WP_011801438.1\|2175442_2175982_-\|peptidoglycan-associated-lipoprotein-Pal	gnl\|CDD\|274307	TIGR02802, Peptidoglycan-associated_lipoprotein, peptidoglycan-associated lipoprotein. Members of this protein are Pal (also called OprL), the Peptidoglycan-Associated Lipoprotein of the Tol-Pal system. The system appears to be involved both in the maintenance of outer membrane integrity and in the import of certain organic molecules as nutrients. Members of this family contain a hydrodrophobic lipoprotein signal sequence, a conserved N-terminal cleavage and modification site, a poorly conserved low-complexity region, together comprising about 65 amino acids, and a well-conserved C-terminal domain. The seed alignment for this model includes only the conserved C-terminal domain.	1.88176e-50
NC_008781.1\|WP_011801434.1\|2171387_2171699_-\|Rieske-2Fe-2S-domain-containing-protein	gnl\|CDD\|239556	cd03474, Rieske_T4moC, Toluene-4-monooxygenase effector protein complex (T4mo), Rieske ferredoxin subunit; The Rieske domain is a [2Fe-2S] cluster binding domain involved in electron transfer. T4mo is a four-protein complex that catalyzes the NADH- and O2-dependent hydroxylation of toluene to form p-cresol. T4mo consists of an NADH oxidoreductase (T4moF), a diiron hydroxylase (T4moH), a catalytic effector protein (T4moD), and a Rieske ferredoxin (T4moC). T4moC contains a Rieske domain and functions as an obligate electron carrier between T4moF and T4moH. Rieske ferredoxins are found as subunits of membrane oxidase complexes, cis-dihydrodiol-forming aromatic dioxygenases, bacterial assimilatory nitrite reductases, and arsenite oxidase. Rieske ferredoxins are also found as soluble electron carriers in bacterial dioxygenase and monooxygenase complexes.	3.97632e-27
NC_008781.1\|WP_011801443.1\|2180350_2182132_+\|lipid-A-export-permease/ATP-binding-protein-MsbA	gnl\|CDD\|131258	TIGR02203, Lipid_A_export_ATP-binding/permease_protein_msbA., lipid A export permease/ATP-binding protein MsbA. This family consists of a single polypeptide chain transporter in the ATP-binding cassette (ABC) transporter family, MsbA, which exports lipid A. It may also act in multidrug resistance. Lipid A, a part of lipopolysaccharide, is found in the outer leaflet of the outer membrane of most Gram-negative bacteria. Members of this family are restricted to the Proteobacteria (although lipid A is more broadly distributed) and often are clustered with lipid A biosynthesis genes. [Cell envelope, Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides, Transport and binding proteins, Other].	0
NC_008781.1\|WP_157040398.1\|2179163_2180354_+\|O-antigen-ligase-domain-containing-protein	gnl\|CDD\|377422	pfam04932, Wzy_C, O-Antigen ligase. This group of bacterial proteins is involved in the synthesis of O-antigen, a lipopolysaccharide found in the outer membrane in gram-negative bacteria. This family includes O-antigen ligases such as E. coli RfaL.	7.85265e-14
NC_008781.1\|WP_011801440.1\|2177330_2178173_-\|glycosyltransferase-family-2-protein	gnl\|CDD\|133042	cd06420, GT2_Chondriotin_Pol_N, N-terminal domain of Chondroitin polymerase functions as a GalNAc transferase. Chondroitin polymerase is a two domain, bi-functional protein. The N-terminal domain functions as a GalNAc transferase. The bacterial chondroitin polymerase catalyzes elongation of the chondroitin chain by alternatively transferring the GlcUA and GalNAc moiety from UDP-GlcUA and UDP-GalNAc to the non-reducing ends of the chondroitin chain. The enzyme consists of N-terminal and C-terminal domains in which the two active sites catalyze the addition of GalNAc and GlcUA, respectively. Chondroitin chains range from 40 to over 100 repeating units of the disaccharide. Sulfated chondroitins are involved in the regulation of various biological functions such as central nervous system development, wound repair, infection, growth factor signaling, and morphogenesis, in addition to its conventional structural roles. In Caenorhabditis elegans, chondroitin is an essential factor for the worm to undergo cytokinesis and cell division. Chondroitin is synthesized as proteoglycans, sulfated and secreted to the cell surface or extracellular matrix.	5.58902e-90
NC_008781.1\|WP_011801428.1\|2165126_2165966_+\|ModD-protein	gnl\|CDD\|238807	cd01573, modD_like, ModD; Quinolinate phosphoribosyl transferase (QAPRTase or QPRTase) present in some modABC operons in bacteria, which are involved in molybdate transport. In general, QPRTases are part of the de novo synthesis pathway of NAD in both prokaryotes and eukaryotes. They catalyse the reaction of quinolinic acid (QA) with 5-phosphoribosyl-1-pyrophosphate (PRPP) in the presence of Mg2+ to produce nicotinic acid mononucleotide (NAMN), pyrophosphate and carbon dioxide.	4.33547e-111
NC_008781.1\|WP_011801432.1\|2168975_2170808_-\|thioredoxin-domain-containing-protein	gnl\|CDD\|224250	COG1331, COG1331, Highly conserved protein containing a thioredoxin domain [Posttranslational modification, protein turnover, chaperones].	0
NC_008781.1\|WP_011801441.1\|2178172_2178940_-\|glycosyltransferase-family-2-protein	gnl\|CDD\|133005	cd02511, Beta4Glucosyltransferase, UDP-glucose LOS-beta-1,4 glucosyltransferase is required for biosynthesis of lipooligosaccharide. UDP-glucose: lipooligosaccharide (LOS) beta-1-4-glucosyltransferase catalyzes the addition of the first residue, glucose, of the lacto-N-neotetrase structure to HepI of the LOS inner core. LOS is the major constituent of the outer leaflet of the outer membrane of gram-positive bacteria. It consists of a short oligosaccharide chain of variable composition (alpha chain) attached to a branched inner core which is lined in turn to lipid A. Beta 1,4 glucosyltransferase is required to attach the alpha chain to the inner core.	1.58148e-95
NC_008781.1\|WP_041377165.1\|2164721_2165108_+\|hypothetical-protein	gnl\|CDD\|238431	cd00851, MTH1175, This uncharacterized conserved protein belongs to a family of iron-molybdenum cluster-binding proteins that includes NifX, NifB, and NifY, all of which are involved in the synthesis of an iron-molybdenum cofactor (FeMo-co) that binds the active site of the dinitrogenase enzyme. This domain is a predicted small-molecule-binding domain (SMBD) with an alpha/beta fold that is present either as a stand-alone domain (e.g. NifX and NifY) or fused to another conserved domain (e.g. NifB) however, its function is still undetermined.The SCOP database suggests that this domain is most similar to structures within the ribonuclease H superfamily. This conserved domain is represented in two of the three major divisions of life (bacteria and archaea).	4.58926e-05
NC_008781.1\|WP_011801439.1\|2176026_2177316_-\|Tol-Pal-system-protein-TolB	gnl\|CDD\|235083	PRK02889, tolB, Tol-Pal system protein TolB.	0
NC_008781.1\|WP_086000566.1\|2173748_2174564_-\|tRNA-threonylcarbamoyladenosine-dehydratase	gnl\|CDD\|224100	COG1179, COG1179, Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1 [Coenzyme metabolism].	7.96678e-91
NC_008781.1\|WP_083758034.1\|2168411_2168954_-\|DUF2845-domain-containing-protein	gnl\|CDD\|371338	pfam11006, DUF2845, Protein of unknown function (DUF2845). This bacterial family of proteins has no known function.	2.09189e-15
NC_008781.1\|WP_011801431.1\|2167903_2168503_-\|pyridoxamine-5'-phosphate-oxidase	gnl\|CDD\|200361	TIGR04110, hypothetical_protein_VSWAT3_12502, heme utilization protein HutZ. Members of this family are heme utilization proteins, typically designated HutZ. They are members of the PPOX family (pfam01243) and, except for the lack of an N-terminal extension, are closely related to one form of heme oxidase (1.14.99.3), HugZ (TIGR04109). Members typically are found in a three-gene operon with radical SAM enzyme HutW and a protein of unknown function, HutX.	2.57718e-17
NC_008781.1\|WP_011801433.1\|2171047_2171296_-\|DUF3297-family-protein	gnl\|CDD\|371696	pfam11730, DUF3297, Protein of unknown function (DUF3297). This family is expressed in Proteobacteria and Actinobacteria. The function is not known.	1.53884e-40
NC_008781.1\|WP_011801435.1\|2171718_2173296_-\|DUF2779-domain-containing-protein	gnl\|CDD\|371365	pfam11074, DUF2779, Domain of unknown function(DUF2779). This domain is conserved in bacteria. The function is not known.	2.64951e-56
NC_008781.1\|WP_011801429.1\|2166051_2166732_+\|molybdate-ABC-transporter-permease-subunit	gnl\|CDD\|226629	COG4149, ModC, ABC-type molybdate transport system, permease component [Inorganic ion transport and metabolism].	9.58225e-84
NC_008781.1\|WP_157040257.1\|2182133_2182781_-\|DUF2726-domain-containing-protein	gnl\|CDD\|371282	pfam10881, DUF2726, Protein of unknown function (DUF2726). This bacterial family of proteins has no known function.	0.00719261

>NC_008781.1|WP_011801435.1|2171718_2173296_-|DUF2779-domain-containing-protein
MRMAFTPLLNHDDLQRWRACSRRFWLHRRGGPAAVSQPSATGAGRTARDADETAEAAVVHGPGLQAALRASFPRADLIAAPGTPAEWAAAVQQTLDCLDSDRVAPEGWAILGACLTSDDRAQVRIDVLTCGEQGLRLFKVRYATVGDEADVDAVALWVHAAARCGLRVQSAGLLLVDTGFIYPGHGCYAGLFREVDLASVLGSRPVAAWLSAMRTCDRGPEPPATPGAQCTQSGGCEFASHCQAGEPASSLPAPDPQASLDIVGRELAAELRQEGHADLRSVALQRLGNLRHRRAARAIQQGGPVLEPAVAALMQALPYPRYSLRFDTIGFAVPLWAGTRPYQVLPFQWTCGVQSAAGQWAQQGFLADADGGDPRRAFALTLLQALGSAGPVLAYNAGFERSRLRELAQQFDDLAPALDAVQARIVDLFQLARAHYYHPVMAGSWSFKSISRAVAPDVPVARLEDVQASSAQAAFARSLQRGLEGAARQQLRAALQAHGQRETEVLRRMAALFEAGAAEAAGIRH
>NC_008781.1|WP_011801434.1|2171387_2171699_-|Rieske-2Fe-2S-domain-containing-protein
MAFQTLCKQRYLAEGESVPFTLDGREVIVLWPDGGQPRAFEGLCPHEGQSLVNNSDFNGRILVCTVHGWVFSGRDGKGLSPTGCQLEEFPLRIAGGMVEIDLD
>NC_008781.1|WP_011801433.1|2171047_2171296_-|DUF3297-family-protein
MNETPQIPPLPDRLSIDPRSPYHMAAVFEHDVCIRLKDKERLDVYEYCISEGWVKVPAGKSLDRKGYPLLIKLTGKVEAFYR
>NC_008781.1|WP_011801432.1|2168975_2170808_-|thioredoxin-domain-containing-protein
MSNRLASQQSAYLLQHAGQPVDWYPWGDEALALARRRGLPILLSIGYAACHWCHVMAAESFSDPAIAALMNEGFVNIKVDREERPDLDAVYQMAHQLLRRTGGGWPLTIFLSPQGVPFYSGTYFPSAAPEGQATFQAVLGSVSAVWREQRPALARQDQALLAALAASAPRRDDAAVPGAAVRAQALQQLATAFDPAQGGFGAAPKFPHPSDLAFLLRRAREEGDAQAREMALLTLRKMAEGGLYDQIGGGFFRYSVDAQWRIPHFEKMLCDNGVLLALYADALALTGEPLFRRVVEDTASWALREMQSSAGGFHASLAADDAQGREGRFYVWESEPLRLALSPNEWDVCAAHWGLVDGPGFEGRHWHLRVARAAGPLAVTLRRPEAQVEELIASARPKLLAERDKRERPARDAKLLTGWTALMMTGLARASAVCQRPEWLLAARSALRFVQAGRWQDDGRTSGHLLALPGQAAFLDDHAFLLEAVLALHDADPQPGDLPFAQAIAKAMLAQFEDRDAGGFFFTRHDAPALIHRLKTGLDAATPSGNGTAALALLALSGKLDAPQAAAYRLAAERCVRVFAATVLNDPASFPRLLQAAELLQATPAVAAAG
>NC_008781.1|WP_083758034.1|2168411_2168954_-|DUF2845-domain-containing-protein
MLAHVQHALEAVFAEICNFKTVDPYSSEVLCFKRSRGLIRERRARYPGRLGRLLCPRPLDAKGGNVKFLIRICLATVVSALFLPVHSETLRCNGHIVEVGDSRLSVRYHCGEPLLQDSYCAPVYYYPGLQPVPEPFASSVVPCLVVDEWLYDRGPGSLVATVRFRAGVVLSITYGARATP
>NC_008781.1|WP_011801431.1|2167903_2168503_-|pyridoxamine-5'-phosphate-oxidase
MTVAPAVSLRRCAFVRAWCFPSRTVRGQRHNFKETLVPHESRLTLELRSLLHSRRVAAMGTIGDDGAPFVSMVPYALEPALGCLVIHVSGLAAHTGNLQARPNVSLLVMQSEADGEPVHALPRVSLDGRARELEVGTPAWDACRAAYVQRFPEAEFMTQLGDFRFVAIELNGARQVAGFGAARSIDAEEVRRALGAAGP
>NC_008781.1|WP_011801430.1|2166733_2167804_+|molybdenum-ABC-transporter-ATP-binding-protein
MTGIQAHFHLDWPGFTLDVNLELPARGVTALFGPSGCGKTTLLRCIAGLERAPQGHLRINGDVWQSDKHWLPTHKRPLGYVFQEASLFPHLTVMGNLRYGMRRISQAQQVSLEQAVDLLGIAHLLERKPAGLSGGERQRVAIARALLTSPRLLLMDEPLAALDLARKNEFMPYLERLHGELDIPVIYVTHAPDEVARLADHIVVMEAGRAIASGPLTETLARLDLPIRLGEDAGVVLDAVVAERDAAWHLARVTFAGGSLWVRDGGQAIGAAVRIRILARDVSIALAHVTGTSIQNCLSATVGEMANDSHPALSLTRLNIGPSPLLARLTRRSAVELGLAPGKPVWVQIKAVALIG
>NC_008781.1|WP_011801429.1|2166051_2166732_+|molybdate-ABC-transporter-permease-subunit
MYLTDSDLQAIWLTVRLAVTVTLILLLIGTPVAWWLARSRAWWKGPIGAVVALPLVLPPSVLGFYLLLAMGPNGPAGHLTQALGIGLLPFTFWGLVIASVFYSLPFMVQPLQTAFEAIGERPLEAAATLRASPLNAFFTVAVPLALPGFLTAGILTFAHTVGEFGVVLMIGGNIPGVTRVVSVQIYDHVEAVEYVQAHRLSAVMLVFSFLVLLALYAWKPDTRKRG
>NC_008781.1|WP_011801428.1|2165126_2165966_+|ModD-protein
MRALNDTQLCSLLDDDTLGGDLTTHSLGLAEQPARLEFRARQPMTVCASEEALRLFELAGSQARLLMRSGSRAGAGELILEAQGDAASLHLAWKTAQNLVEWASGIASATAAIVAAAGGVAVACTRKNVPGTKALSIKAVRAGGGGIMHRLGLSETLLVFAEHRLFLTDTPAQTIAQLRRTQPEKKIIVEVGDPGEALRWALAGADVLQLEKFTPEAVATCREALQAFPAASRPLLAAAGGVRAGNASAYVAAGADLLVTSAPYTAPPQDVQVTFFVNA
>NC_008781.1|WP_041377165.1|2164721_2165108_+|hypothetical-protein
MKIAIATKDHWTQVSGHAGQSRDWLVFDCLPGQPLPEPLRIQLSKEQLPHHFQDDGPHPLHGIEVMVAASAGDGFIRHMEKWNAQVLLTGETEPLAALAKILAGEALPDTRFDVTTSLCKLRDLFSRH
>NC_008781.1|WP_086000566.1|2173748_2174564_-|tRNA-threonylcarbamoyladenosine-dehydratase
MIAPDLGRRFGGLARLYGAAGAERIRNAHIVVVGLGGVGSWAAEAAARSGVARLTLIDLDHVAESNINRQVHALDTTVGQAKVQAMRERIAHINPDCRVDCIEDFVDAANWPGLFSPDMRFDHQHLAVIDACDQVRAKTAMAAWAIKNKAILISVGAAGGKRLAHRVDIDDLSAVTHDPLLAQMRYRLRKEHEAARLGRMNVMCVFSRESVARPLTAVDVGPAHADTAVQPLAVPMQPDGSLNCHGYGSVVSVTSTFGMCAASWVLDKIAS
>NC_008781.1|WP_011801437.1|2174665_2175427_-|tol-pal-system-protein-YbgF
MKTFRLFIAVAACVLAFNANAALFEDDEARRAILDLRQKVDVSQQRTTEELRKANEDNAQLRRSLLDLSNQIESLRNEMATLRGQNEQLTRGITDVQRTQKDITQGVDERLRKVEPSKVSVDGREFAAEPAEKQEFEAALASLRKGEFAAAQTSFTAFTKRYPQSGYKSSALFWLANAQYALRDYKSAVNNFRTVASADPEHVRAPEALLSMANCQVELKDAKSARKTLEELVKTYPQSEAASVAKERLSKLK
>NC_008781.1|WP_011801438.1|2175442_2175982_-|peptidoglycan-associated-lipoprotein-Pal
MKRFLSSVISSLVLAATLVACGSNVKLQDVPVEDRSASSSQADADAAAAASRGVAPVQIGASDASVAGPANTAKIVYFDFDSYVVKPEFQSVIEAHARYLTANKARKMAIEGHTDEIGGREYNLALGQKRAEAVRRALGLLGVTDSQVEAVSFGKEKPAVPGLDEASMAKNRRAEINYR
>NC_008781.1|WP_011801439.1|2176026_2177316_-|Tol-Pal-system-protein-TolB
MSITPSFSRRSVVSLLAAGAFSSMSAFAQFRVEVSGVGMTQLPIAIAPFRGEAQSPQKIGSIVKADLERSGMFRGVDAGGVVADENTRPDLASWRQKGADAMVTGSVSPLADGRFDVRLRLWDVVREQDLGGQSYTVTKSDLRLSAHRVSDFVYEKLTGEKGIFSTRIAYVTKAGQRYTLWVADSDGESAQSALASPEPIISPAWSPSGAQLAYVSFESRKPVIYSHDVATGKRRLLANFRGSNSAPAWSPDGSQLVATLSQAGGSQIYSIGLNGGDPKRLTQSSSIDTEPAFSPDGRLIYFVSDRGGSPQIYRMSPAGGNAERVTFTGSYNISPVVSPDGRWLAYVSRVGGGFKLHVMELSTGTVTSITDTSADESPSFAPNSRLIVYATQQQGKEALMTTTLDGKIKARLSGAGGDIREPDWGPFQR
>NC_008781.1|WP_011801440.1|2177330_2178173_-|glycosyltransferase-family-2-protein
MKISFIVLTYNRTDALLAVLRSLAEQCNPEHEVLIADDGSRQDQVEMLLERCPAFSCPVRHVWHPDVGFTAAGARNLAAHVAKGDYLVFLDGDCIPNKSFVAWHTLLAESGFFVNGSRVLLNKTLTAEVLSGEVNLPHCSAFFWFRARFQGDSNKLLHLIRWPLSLFRVQQDFQWRGIRSCNFGVWRHDFVSVNGFDETFQGWGHEDADLVLRLHHLGLKRKNGFMATEVFHLWHPESKRDQESVNKNRVMARMKTNLVLAEKGLRELDTAAPLKITQLH
>NC_008781.1|WP_011801441.1|2178172_2178940_-|glycosyltransferase-family-2-protein
MPSLSVTVITKNEAHNIEACLRSVAFADEVIVLDSGSTDNTVQIALSMGADVSTNSDWKGFGVQKNRALALAKSDWVLSIDADERVPAELQAEIRAALEASDFDVYSMPRLSSYCGQYMHHSGWYPDRVTRLFRRHSARFSDDLVHEKIVTTSKVGQLNSRLLHESFNNLEAVLDKTNRYSTAGAQSLFNKGKPASVGKALGHGMWAFVRTYFLRLGFLDGRLGLVLAISNAEGTYYRYLKLWLLQRQPGKVPPA
>NC_008781.1|WP_157040398.1|2179163_2180354_+|O-antigen-ligase-domain-containing-protein
MVLISIAKLLLVIFGLAVVLFARRAPAAGSPLTGMSTPVAVLLAFFAFALSLFWTVAPQAEALGSLAKYGKLITIVLMVLIIRDRREANYALGAFVAAQTFLLASSWMLFARLALPWATSRMALTEYSVFSSYLDQGIMSAVFAGICWHFREHAPGRFGSRLAVFLALAALANVLFILSGRTGHVVAIALVSLAIMWELPKKYRAMVVLLPFLLALGLFFSSSKVRDRLTKVETEVQSYSTQAEPVTSSGIRLNLWRRAIQSIGQHPLAGSGVGSWSSEFNRLQRAQNPAHIDIDSNGNPHQEYLLWGVQLGIPGMLLFLALLLSVLRDTLKMDKPYSRAAQSTLLALAIACLFNSSLYDAQIGDFFCILMGLLLALGLKKVPDLHIATHHYKQAV
>NC_008781.1|WP_011801443.1|2180350_2182132_+|lipid-A-export-permease/ATP-binding-protein-MsbA
MTKTPKLTLLRRLARVWPYFSGSRAGWALAIGATIVASATEPFVPALLKPLLDRGFQRDSFNLWLVPVTLMLLFIIRGLSGFLAQFALAKVTNDGLLQLRKAMFDKLLSARLTLFADQSSSMIANTVVYEVFNGSSSLINAIMRLARDVLTLLALIGYLVYLNWKLTLIVGFLFPAVAFVIQVLSKRLYRLTKESQTATDSLAYVVEENVMAHRDVRLHGAQASQASRFDSLSHSLRRLSMKSTAAYAGMSAITQVLAAMALSAVISIALMQSAENTTTVGGFVAFVTAMLLLIAPIKSLSDAATPVTRGLAALERGLDLMDLTPNETSGSFVKARAVGAIEFSSVTVAYKTDTTPVLQDFNLCVTAGETLAIVGASGSGKTTLVNLLPRFVEISAGSITLDDQDIRDWNLASLRSQFAFVSQHVVMLNSSIAENVALGQPIDPARVKECLEAANLASLLAGLPEGLDTVLGHNAMQLSGGQRQRLAIARALYKDAPILVLDEATSALDTESEIAVQDAVRRLTSGRTSLVIAHRLSTIQNADRIIMMDAGRIIESGTHKELLAKNGAFAHLYRLGFQSSSPVQAAPIQPLNV
>NC_008781.1|WP_157040257.1|2182133_2182781_-|DUF2726-domain-containing-protein
MNEWTVIAAGVGLLAGMALGALLWAWWLRRPKDGDRLHLPARWPLRGRPIVNGNEQEVWQALRQIFPDHAVVVKIPILRFTKLHEARDLNSSKRSAKARADDRLKSEQWLEMLDGLYATFTVCTLKGKVVGCVDVPGKLALTKASRELKEALLLDCGIAYTVVNAFNLPDASTMRELFLGELPVQTLEHQVTRGGDSEFHADLAAFTLQQAGGAS
>NC_008781.1|WP_157040258.1|2183113_2183254_+|hypothetical-protein
MNLLDKIAASAGSPSLARDNARTWNKYLVRVDNQRFSVAVPVLPVH

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Crispr_ID: NC_008781_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_008781_2

3456665-3456779

Orphan

Consensus_repeat	Method
GCCCCCTCGGGGGGCAGCGAACCACTCGAAG	CRISPRCasFinder

1 spacers

DEDDh

The CRISPR arrays of NC_008781_2

>merge|NC_008781|2|3456665-3456779|CRISPRCasFinder
GCCCCCTCGGGGGGCAGCGAACCACTCGAAGAGGGGAGCGTGGGGGTCAGTCGTCCCGCCGACAGGCCGCCCTTAGGCGGGACAGCCCCCTCGGGGGGCAGCGAACCACACGAAG

>NC_008781|2|2|3456665-3456779|CRISPRCasFinder
GCCCCCTCGGGGGGCAGCGAACCACTCGAAG	AGGGGAGCGTGGGGGTCAGTCGTCCCGCCGACAGGCCGCCCTTAGGCGGGACA
GCCCCCTCGGGGGGCAGCGAACCACACGAAG

Protein	Signature genes	Signature genes Name	Protein_function
NC_008781.1\|WP_011802617.1\|3450400_3450598_-\|hypothetical-protein	unknown	unknown	unknown
NC_008781.1\|WP_157040311.1\|3450651_3451782_-\|patatin-like-phospholipase-family-protein	unknown	unknown	gnl\|CDD\|224666
NC_008781.1\|WP_011802615.1\|3448191_3449178_+\|DUF58-domain-containing-protein	unknown	unknown	gnl\|CDD\|224635
NC_008781.1\|WP_011802616.1\|3449199_3450264_+\|VWA-domain-containing-protein	unknown	unknown	gnl\|CDD\|184242
NC_008781.1\|WP_011802629.1\|3462299_3462698_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|181433
NC_008781.1\|WP_049763704.1\|3458090_3459065_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|226706
NC_008781.1\|WP_049763775.1\|3455850_3456579_-\|lipoprotein-releasing-ABC-transporter-ATP-binding-protein-LolD	unknown	unknown	gnl\|CDD\|131266
NC_008781.1\|WP_011802634.1\|3470541_3470772_-\|hypothetical-protein	unknown	unknown	unknown
NC_008781.1\|WP_049763705.1\|3469135_3470395_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|380191
NC_008781.1\|WP_011802628.1\|3461142_3462267_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|270238
NC_008781.1\|WP_041377367.1\|3454055_3454637_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|368953
NC_008781.1\|WP_011802619.1\|3451884_3453219_-\|hypothetical-protein	unknown	unknown	unknown
NC_008781.1\|WP_011802623.1\|3455259_3455757_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|173412
NC_008781.1\|WP_011802622.1\|3454694_3454970_-\|J-domain-containing-protein	unknown	unknown	gnl\|CDD\|274090
NC_008781.1\|WP_011802631.1\|3465900_3467301_-\|Fic-family-protein	unknown	unknown	gnl\|CDD\|225718
NC_008781.1\|WP_011802632.1\|3467480_3469133_-\|exonuclease	DEDDh	cd06127_DEDDh_CAS-I	gnl\|CDD\|176648
NC_008781.1\|WP_011802620.1\|3453254_3454007_-\|hypothetical-protein	unknown	unknown	unknown
NC_008781.1\|WP_011802625.1\|3456799_3458056_-\|lipoprotein-releasing-ABC-transporter-permease-subunit	unknown	unknown	gnl\|CDD\|274034
NC_008781.1\|WP_011802627.1\|3459111_3460854_+\|single-stranded-DNA-specific-exonuclease-RecJ	unknown	unknown	gnl\|CDD\|182944
NC_008781.1\|WP_011802630.1\|3462747_3465753_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|372732

Protein	Function_ID	Function_description	E-value
NC_008781.1\|WP_157040311.1\|3450651_3451782_-\|patatin-like-phospholipase-family-protein	gnl\|CDD\|224666	COG1752, RssA, Predicted esterase of the alpha-beta hydrolase superfamily [General function prediction only].	1.26534e-32
NC_008781.1\|WP_011802615.1\|3448191_3449178_+\|DUF58-domain-containing-protein	gnl\|CDD\|224635	COG1721, COG1721, Uncharacterized conserved protein (some members contain a von Willebrand factor type A (vWA) domain) [General function prediction only].	7.49636e-30
NC_008781.1\|WP_011802616.1\|3449199_3450264_+\|VWA-domain-containing-protein	gnl\|CDD\|184242	PRK13685, PRK13685, hypothetical protein; Provisional.	3.30946e-58
NC_008781.1\|WP_011802629.1\|3462299_3462698_-\|hypothetical-protein	gnl\|CDD\|181433	PRK08455, fliL, flagellar basal body-associated protein FliL; Reviewed.	2.55962e-05
NC_008781.1\|WP_049763775.1\|3455850_3456579_-\|lipoprotein-releasing-ABC-transporter-ATP-binding-protein-LolD	gnl\|CDD\|131266	TIGR02211, LolD_lipo_ex, lipoprotein releasing system, ATP-binding protein. This model represents LolD, a member of the ABC transporter family (pfam00005). LolD is involved in localization of lipoproteins in some bacteria. It works with a transmembrane protein LolC, which in some species is a paralogous pair LolC and LolE. Depending on whether the residue immediately following the new, modified N-terminal Cys residue, the nascent lipoprotein may be carried further by LolA and LolB to the outer membrane, or remain at the inner membrane. The top scoring proteins excluded by this model include homologs from the archaeal genus Methanosarcina. [Protein fate, Protein and peptide secretion and trafficking].	7.13949e-116
NC_008781.1\|WP_049763704.1\|3458090_3459065_+\|hypothetical-protein	gnl\|CDD\|226706	COG4255, COG4255, Uncharacterized protein conserved in bacteria [Function unknown].	1.73061e-19
NC_008781.1\|WP_049763705.1\|3469135_3470395_-\|hypothetical-protein	gnl\|CDD\|380191	NF033187, internalin_J, class 1 internalin InlJ. Internalins, as found in the intracellular human pathogen Listeria monocytogenes, are paralogous surface-anchored proteins with an N-terminal signal peptide, leucine-rich repeats, and a C-terminal LPXTG processing and cell surface anchoring site. See PMID:17764999 for a general discussion of internalins. Members of this family are internalin J (InlJ).	2.05785e-39
NC_008781.1\|WP_011802628.1\|3461142_3462267_-\|hypothetical-protein	gnl\|CDD\|270238	cd13520, PBP2_TAXI_TRAP, Substrate binding domain of TAXI proteins of the tripartite ATP-independent periplasmic transporters; the type 2 periplasmic binding protein fold. This group includes Thermus thermophilus GluBP (TtGluBP) of TAXI-TRAP family and closely related proteins. TRAP transporters are ubiquitous in prokaryotes, but absent from eukaryotes. They are comprised of an SBP (substrate-binding protein) of the DctP or TAXI families and two unequally sized integral membrane components. Although TtGluBP is predicted to be an L-glutamate and/or an L-glutamine-binding protein, the substrate spectrum of TAXI proteins remains to be defined. A sequence-homology search also shows that TtGluBP shares low sequence homology with putative immunogenic proteins of uncharacterized function. The substrate-binding domain of TAXI proteins belongs to the type 2 periplasmic-binding fold protein (PBP2) superfamily, whose members are involved in chemotaxis and uptake of nutrients and other small molecules from the extracellular space as a primary receptor. PBP2 typically comprises of two globular subdomains connected by a flexible hinge and bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap. After binding their specific ligand with high affinity, they can interact with a cognate membrane transport complex comprised of two integral membrane domains and tworeceptor cytoplasmically located ATPase domains. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis.	2.48556e-17
NC_008781.1\|WP_041377367.1\|3454055_3454637_-\|hypothetical-protein	gnl\|CDD\|368953	pfam06524, NOA36, NOA36 protein. This family consists of several NOA36 proteins which contain 29 highly conserved cysteine residues. The function of this protein is unknown.	0.00135452
NC_008781.1\|WP_011802623.1\|3455259_3455757_+\|hypothetical-protein	gnl\|CDD\|173412	PTZ00121, PTZ00121, MAEBL; Provisional.	3.87447e-05
NC_008781.1\|WP_011802622.1\|3454694_3454970_-\|J-domain-containing-protein	gnl\|CDD\|274090	TIGR02349, Chaperone_protein_DnaJ, chaperone protein DnaJ. This model represents bacterial forms of DnaJ, part of the DnaK-DnaJ-GrpE chaperone system. The three components typically are encoded by consecutive genes. DnaJ homologs occur in many genomes, typically not near DnaK and GrpE-like genes; most such genes are not included by this family. Eukaryotic (mitochondrial and chloroplast) forms are not included in the scope of this family.	4.79146e-25
NC_008781.1\|WP_011802631.1\|3465900_3467301_-\|Fic-family-protein	gnl\|CDD\|225718	COG3177, COG3177, Fic family protein [Function unknown].	1.93253e-14
NC_008781.1\|WP_011802632.1\|3467480_3469133_-\|exonuclease	gnl\|CDD\|176648	cd06127, DEDDh, DEDDh 3'-5' exonuclease domain family. DEDDh exonucleases, part of the DnaQ-like (or DEDD) exonuclease superfamily, catalyze the excision of nucleoside monophosphates at the DNA or RNA termini in the 3'-5' direction. These proteins contain four invariant acidic residues in three conserved sequence motifs termed ExoI, ExoII and ExoIII. DEDDh exonucleases are classified as such because of the presence of specific Hx(4)D conserved pattern at the ExoIII motif. The four conserved acidic residues are clustered around the active site and serve as ligands for the two metal ions required for catalysis. Most DEDDh exonucleases are the proofreading subunits (epsilon) or domains of bacterial DNA polymerase III, the main replicating enzyme in bacteria, which functions as the chromosomal replicase. Other members include other DNA and RNA exonucleases such as RNase T, Oligoribonuclease, and RNA exonuclease (REX), among others.	4.08019e-28
NC_008781.1\|WP_011802625.1\|3456799_3458056_-\|lipoprotein-releasing-ABC-transporter-permease-subunit	gnl\|CDD\|274034	TIGR02212, releasing_system_transmembrane_protein_lolC., lipoprotein releasing system, transmembrane protein, LolC/E family. This model describes the LolC protein, and its paralog LolE found in some species. These proteins are homologous to permease proteins of ABC transporters. In some species, two paralogs occur, designated LolC and LolE. In others, a single form is found and tends to be designated LolC. [Protein fate, Protein and peptide secretion and trafficking].	3.32642e-156
NC_008781.1\|WP_011802627.1\|3459111_3460854_+\|single-stranded-DNA-specific-exonuclease-RecJ	gnl\|CDD\|182944	PRK11070, PRK11070, single-stranded-DNA-specific exonuclease RecJ.	0
NC_008781.1\|WP_011802630.1\|3462747_3465753_-\|hypothetical-protein	gnl\|CDD\|372732	pfam13809, Tubulin_2, Tubulin like. Many of the residues conserved in Tubulin, pfam00091, are also highly conserved in this family.	4.55038e-84

>NC_008781.1|WP_049763775.1|3455850_3456579_-|lipoprotein-releasing-ABC-transporter-ATP-binding-protein-LolD
MGEGRDGGLPEPAQPQGEVVLRASALTKRFTEGRLDVTVLQGVDLQVHRGETLAIVGTSGSGKSTLLHLMGGLDAPTSGQVELKGQLLSSLSPASQGELRNRHLGFVYQFHHLLPEFSALDNVAMPLWIRRLPRDECARIATKMLASVGLEDRIYHRPAELSGGERQRVAIARALVTQPACVLADEPTGNLDRVTADGVFQLMLKLAREHGTAFVMVTHDEALAARCGRQLRLVLGKLSEAD
>NC_008781.1|WP_011802623.1|3455259_3455757_+|hypothetical-protein
MNKLLATLIAGLFVSGAFAQAPAAPATMPAATPAVVKAEVKADNAAVKAVAAEAKVDAKADAKVEKADMTASKTKVKAKAKAHKAKSKAHAKAVKAAPQDKVAAEAKAEKVDVKADAKADKAVVNATAKADKVKVEAKADKMNAATETAAVKAEGKADVKAATVK
>NC_008781.1|WP_011802622.1|3454694_3454970_-|J-domain-containing-protein
MTDHYTTLGLSSAATLADVKKAFRQKASFWHPDKNAAPAAPARFRAVQQAYEVLSDADRRQAYDDNRRRNLLDSPLETAREIWTPYFNQLL
>NC_008781.1|WP_041377367.1|3454055_3454637_-|hypothetical-protein
MNISPFFINLHSAYQAEMDDLTFDSDGRDVLRQRLAAKRKEIGFLVQMMELSPEMVAVIFHQGFAFSQPAAMDHLLSHEADEFPEWSSLSGGIELAPWTRELVQVILQAPKGEWFLTLAAGLHYMAGKPVAAFAGQGGEARDEDSDDGDDDDDDTDGPDDFDDHESDEVRGDARDRDAAGASWLEGHGFDRKD
>NC_008781.1|WP_011802620.1|3453254_3454007_-|hypothetical-protein
MNHLALIEKTQTLIAAGDIVGAESALVELADTEGDSALMVVLDLLPAKDILAVIREYDNSKESIVNLLVTPEQFARAVVIEKQYKDLTRTHLRGMMNAIIFREDADPLEFLTAIGDLEGGSEALADYFTEKWDRIEAFACNGTFDAMKDTGELRSKADLQAVAYEKPRVEQDEISDHDWMELAWLLRYEIPDLFIEMLTVLRAKARAHDLGLDEEEDDEMQDDDGKVETGDTDRGRATPAARESDEESAI
>NC_008781.1|WP_011802619.1|3451884_3453219_-|hypothetical-protein
MPMHPSATAPTASPTSPASVSLYDARPFFEKALQFGVQNGIIDREKLDAIRTDAPKGMVQIARYFGNEFLRPDLEKAKDRIVNLVSLYLQSSCGGDLRQAAESLRDHSFLSRSKGGSDLLKALLALPESTVFHASLDSGAEAGGPPKGLAEWSLKSFADYQAELARRRPLQQEKDAAIWLAGELGMDAEELEEAHTHAEAVIRTALLAMATRRTEMPDWVEFEKMVAALRKKYRAAKTRTAVQAGKTSSASARSLTLSLALPANLPDEFRDVVQAVLQSVQADLPQILDSALTVRALFANDSEDHHPPLLGRYFWVEDIASEMDHHERSVSQAWDKVTGGNCDDGSLLTLMVCVAAGAAPKTILSEKAATALVRKIQKPGAKAAFSPELARQYILEHAPVQHQDAYLQLWADFMDEAQSTLQSDSTYALKDALALLRRECHVTA
>NC_008781.1|WP_157040311.1|3450651_3451782_-|patatin-like-phospholipase-family-protein
MFQPGVESGRHAECVAPKPRACSSIALHNDRQEAPLLFERRSPQPISLALQGGGAHGAFTWGVLDHLLEDGRVDFEGVSGTSAGAMNAVVLAHGLNDGGRDGARAALHRFWTSVADSLPFEVAVPSLDGQNVSLLPALKMMMHWAHYFSPHQLNPFDLNPLRDILLAQVDFERLRGDSPVKLFIAATNANSGKVRLFRSPEISAEAILASACLPTMARPVEIDGEPYWDGGYAANPAVYPLFYECKSSDILMVLLTPMKHKGTPHSAQEIKDRVLELAFNSTFLREMRMFAHAREYAKESFFRIGRFERRLVQTNFHVIDAPEQMNEFKTETKLAANMQFFELLRNLGRERARGWLEANHGEIGRRSTVDLAELFY
>NC_008781.1|WP_011802617.1|3450400_3450598_-|hypothetical-protein
MKNPFMSMFLSGANKIAGAARAQATAAVKREAAKNTKEMTKAWTDALMPKAPTAAAPRKRKTTRK
>NC_008781.1|WP_011802616.1|3449199_3450264_+|VWA-domain-containing-protein
MNLPVNFLWPQFLWLLLALPLLVAVYVWLLRRKKKMALRYASLSIVREAIGTGQSVRRHIPPLLFLLSLAVMLVAASRPLAVITLPSQNETIILAMDVSGSMRATDVLPNRLVASQNAAKAFLADLPRNVRVGVVAFAGTAAVVQPPTVSREDLTAAIDKFQLQRGTAIGNGIIVSLAELFPEAGIDLESMENNRERKHGLSLDQAGKDDGNGKKAFTPVAPGSYTSAAIILLTDGQRTTGIDSLDAAKVAADRGIRVYTVGVGTVEGETIGFEGWSMRVKLDEETLKGIARATQAEYFYAGTATDLKKVYQTLSSRLTVEKKETEISGLLALAAAVLGLLSASLSLLWFNRIL
>NC_008781.1|WP_011802615.1|3448191_3449178_+|DUF58-domain-containing-protein
MPKLSQVVQTPASSTPAESADQLLRRLEWTVLRRLDGLLQGDYRTLLRGTGMDLADLREYQYHDDVRHIDWNVTARLQQPHVRVFTEDREMSAWFLLDLSPSMDFGSSEQRKRHVLTDFVAVLARMLTKHGNRVGALLYGAGVDAAIPARGGRQHVLHLLHTLRTRPEAASAGATRLHELLESAAKLVRRRSTLFVVSDFITEAGWEKPLGLLAQRHEVVAVRLLDPLELELPDLGLIPITDAETGEQLLVDTHDAGFRRRFARIAAQREAELRQALARAGVDTLELSTDDDLAGAIMRFTDLRKQRSRLSGAHAAAGRLPAHLAHAG
>NC_008781.1|WP_011802625.1|3456799_3458056_-|lipoprotein-releasing-ABC-transporter-permease-subunit
MQIPYELILGWRYTRAGRATRRNGFISFISGVSMLGIALGVAALIIVLSVMNGFQKEVRDRMLGVISHIEVFAPGGGALADPQKTLAEIRANPNVVGAATFIAAQALLARGEDMKGTMVRGIDPALEGQVTDLAVELEKTSFPKLVSGQFGVVLGGELARAMGVREGDTVTLIAPSGQVTPAGVVPRLKTMTVVGTFDSGHFEYDSALVMMHQDDAAKIFRLEGPTGIRIKLKDLHQARQVALELSQTLSGDLLIRDWTRQNKTWFAAVELEKRMMFIILTLIVAVAAFNLVSTLVMTVTDKRADIAILRTLGASPKSIMGVFMVQGAMVGVIGTLSGLLLGLGIAFNIDVIVPALERLLNASFLPKDIYLISRMPSEPQYADIMPIVVISLVLAFLATIYPSWRASRVNPAEALRYE
>NC_008781.1|WP_049763704.1|3458090_3459065_+|hypothetical-protein
MHPLSPTHLLIPFAACSAEAWLPTVQALPPDSFKRLGQLLQGMKLVENDTQNPESLSPPHERALARALGLATLQTPDGLMPWAASDAAQHLQAGHGKAWAWITPCHWAMGHLHATLSDPAMLELPESESRALLAIMQPYFETDGITLHYLSAGRWLAEGELFRDLPTASLDRVLARNVDAWLPGSAQARPLRRLQNEIQMLLYIHPFNDAREMQRQVPVNSFWISGTGDLPAPTEQPKEQVSAPRSLAQAVFREDWAGYAQAWATLDAGEIAALLARQRAGENVRLTLCGEHSAQTFETHRAGLLTRISSLLSPLRTLDVLKQL
>NC_008781.1|WP_011802627.1|3459111_3460854_+|single-stranded-DNA-specific-exonuclease-RecJ
MKIQVRDVPPRSLWALQQAGIHPLLAQLYAARGVHAAAELDDGLARLLPPSSLKGAREAAILLADAMAAGKHICVVADYDCDGATACAVALRGLKLLGATNVGYLVPDRVVDGYGLTAPIAERVKATGADVLVTVDNGIASIDGVARAKALGLQVLVTDHHLPALFNEKIGLPDADVIVNPNQPGCGFESKSMAGVGVMFYVLLALRAELRERGAFDAAHQPKLDTLLPLVALGTVADVVKLDANNRRLVAQGLKRIRAGALPAGIASLFKAAGRQAPAATTFDFGFALGPRINAAGRLADMRLGIECLLTDDPARADELAQMLDGINRERRQIESGMRDQAQLAADAMIDEDEEPPPAIAIFDPEFHEGVVGIVASRIKDKLHRPTFVFAASQAPGKEHELKGSGRSIPGFHLRDALDLVAKRHPGVLLRFGGHAMAAGCTIAEENFEAFEYGLQQVAREWLDAATLTRRLETDGPLAPEYRRADLVDTLHKEVWGQGFAAPTFSEEVEVVSQRLVGDDKHLSLKLKHRGEPVDGIWFGHTDALPARVTLAFRLDTNEWKGIRRVQFLIEAAEIRPQER
>NC_008781.1|WP_011802628.1|3461142_3462267_-|hypothetical-protein
MNQSPKKWMRGLSVLAGICAAAAALSAGAESIVTGGKTGTYYAIGSNLRDFVNPALEVKDSKGSWANVEDMSRTKGVTLAIVQSDVYSAFVQLRDSKEVPEATRREYAQLLANLRVFMPLYKEEIHFLARKDDPIEFIHQIKGKPLWMDMEKSGTYLTALNIYSKLFQERPNAVEPFINTTATGEDEGTKRRRSALMALSDPAYYKAYPKIDVMVLVGGQPLGLLEKNLPPNLKLLKFDPAQPGAAKVLQDYQKAAIQKSSYPLLNIAGSESPSLAVDSYLITANFADPQRNQYIKDFADQFCTNFGVLQERGHAKWKSLTWQPGSSLPPVAAGWQYSDKVKERLASCRTSAAAATAAKPSACSPQDRVTGLCR
>NC_008781.1|WP_011802629.1|3462299_3462698_-|hypothetical-protein
MASLTGKSGKCSNFGNCSLADARTTIEVPNGMDFVCTECGKPLLLTDPGPQGGGNSRALAVGALLLVLLLAAGGIGWSLMSGKKAPAPEPAPPVAVEQPQAPPKAEPAVQPPVTGNCSDADERVGLCRRPAQ
>NC_008781.1|WP_011802630.1|3462747_3465753_-|hypothetical-protein
MNHFIIGLGGTGGKIIRALRKSLYQEFHGGPPAGVGIGYLYVDSSSEMMAMDDPTWKTLGTSVQLSKASQLLITDANLTSRLDNLDSYPGLKHWLGSPQEWRDILNSIVGATLGGQKRRLGRFLFACKADKYREQVQTQVKLLQQSGETDVTFHIVVGLAGGTGSGSVIDAVAQLRDLYPDSKRFRILIYALLPDAYPHPNWDTGNYHANGFAALTELNAMSVGAYQPYDVTGVKQRLTLSDPFNGCYIFGNENENGLTVDVDKDLPGIVADFLYQKIVAVNNVNWASLGRMENAENGDGSPETAPQGRMPERSKRFLAFGIKRLAIPEEEISEYLTYSFARQAALQLRFNHWQPASGFIDEPRKLDFNEFVQQKETQLRWLLSDDHLTLALGILPEDAANKRWKSFTGEWEAVIPNFKSLVRERERATWLDELTKLCEKRFQDDYRTLGVAGFYRTKLKARKDMAREIRTRIEQELINEWKVGAKSAWDVSRLLIALTETLDERLKACDDNVVRARNAEEQAQSRVLGNLQKWSGMSLLSKHLLGTPDSLLDAHGVHLQEMYVYRTRAEGWGFAKALLIEVIAEITDLKGEVDRVATTLQQALKKFEVGIQARLNDAGSGDLRQHLIRFYDPVQVKTISRRLVLDEAEQKTQSGRVRAALIEKIGPDAGFAQFNQRVPESAFLDVLETVCEDNARIAHQNLVQNPKERLLGVSIIDKLRDRYGADPQELKSYVNELVSRAGNFVALEPLEIHRAAPGIPLGVPTAVGKFTVILPKAPEQAEFSRVLKDALREAKTGDVEIIESDGRLNEITLVSITNLLPLRYLKPLKFLEEKYRRRIDTGGARARLELHTEGDGNAWPRLFVASSAEVKLQALPYVLLAKALGFIHEGRNPATGADEVLLLTKDADGFDNDPVALGKSFMASADSIDLANLHTIKSVCNAMLAGAAYLHQDRRTEVQRAILAEVEAVKAARGGNIQDETYRRFLDAGRRAVAILKGEAA
>NC_008781.1|WP_011802631.1|3465900_3467301_-|Fic-family-protein
MTQTETLALIEALIAERPQGIGIAELEKSLAQRTGAAVQRRTLQRRLERLLKDRRIIAEGQSIALVYKPALPGAAASVAEAQPGVEAELYVPVSPEGTAIRARVRLPLMHRRPVGYQREFLEAYRPGVTFYLPESLRAQLHEMGRTPVGGRPAGTYARDIMNRLLVDLSWASSRLEGNTYSRLDTQNLIEFGQIAKGKDAQETQMILNHKAAIEMLIEDAEQVGFDAFTFQNLHAVLSQNLLREEAACGRLRRRPVEISGTVFQPLAMPQVLEDCFRLLLQKADAIPDPFEQAFFLMVQLPYLQPFEDVNKRVSRIGANIPLIKHNLCPLSFIDVPERAYVEGTLGVYELNRVELLQDVFVWAYERSCQRYLAITQSMVEPDPLKIKYREALIEAVQSVVKGLQAPDPQTVAQLAAKLASAADQQAFAQLLTDALRQLHEGSVVRWRLKRSEFLAWQAHRPVFPKK
>NC_008781.1|WP_011802632.1|3467480_3469133_-|exonuclease
MNHQAWVLIDTETTGLTVPIFVVELGAQRMRGWLPEGSPFRRLLNQNLDIPPASSRVHGYTREILERDGEPAAVVYRDFAAYAGGLPVVAFNLEYDLDEVLLPEWKRLGITPMVTAGFCALRLAQRLLDPVPAGNCKLQTLRQYYRLPERGAHTALGDVETVADLLAKVLRPIAEQRQLHSWADICAYAEAEWFPSRIAFGKFKGRQVQDARTDSALRGWLQWLSNSANTRSASMGRWYLQQLERGDAQSETPVTVTAAANGDTPPAAGSAAPQAGIVVFVNPEIGALRQLIAAARTQLAELEAGYMKDRHAVDLTQAAIFNLVRGHYQQRDRLKLVIDYRSLYLKTLLRSGEDEAAQVAEDYEQAKAQSDAHYEQAQTAAASRKALSSDEEAELKTLWKKLVRLYHPDRFAHQPDKLETYHHLTSAINQARENGDIARLREIAHDPHGFILRHGWVSLDFGDEAELKNLRRLLDTLQLEIVTTLDSRNSLHESAEFELCQLCTQTPGLLEEVAAGQMEVIAAEIAQLQAQAGQLEADIAELTGEDAAIE
>NC_008781.1|WP_049763705.1|3469135_3470395_-|hypothetical-protein
MADKERNVLIPLPAGGLENIGSGPKSILSGMVSDALALARMREKSLAEKRFRIGDYEFRDPDYRQILIWAKALEIEPEVFIRSFEDDSFSQDGNVLRLDVEDGSIVLLQWDFDIFPISSFEWVDGLRIQQLGFKGIASAELSLRLPLLNCLDCHDIGLTKLDLSNLPELTYLECGDNQLVELDLLNVPGLTDIYCSNNQLVKLDLSNVPKLTQLLCENNQLTQLDLSNVLGLTLLWCSSNSLIELNLSNVQKLTDLWCSTNQLTELDLSDVSGLKELHCNENQLVELDLSNVPELTELNCDNNQLTELDLSNVSKLKHLRCQKNQLAKLDLSNVPGLTGLDCSNNQIVKLDLANVQRLIGIFCGKNQLAELDLSNVPGLTTLWCRSNPLAELDIRWLVKLKRFACDPSVTLQKLPTQNF
>NC_008781.1|WP_011802634.1|3470541_3470772_-|hypothetical-protein
MIRGDAFDQRAALCAAAPNGQNREVFKENQALAHTGYAQPAIKLVVILGLKQTVADAAVRLTQQADDRQPQAASGH

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Crispr_ID: NC_008781_3

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_008781_3

3525771-3525859

Orphan

Consensus_repeat	Method
TGCCCCCCGCAGAATCTGCACCC	CRISPRCasFinder

1 spacers

The CRISPR arrays of NC_008781_3

>merge|NC_008781|3|3525771-3525859|CRISPRCasFinder
TGCCCCCCGCAGAATCTGCACCCCCCGCTACCGATTTGGGTACGCCACCCCCGCAAATTCACGTACTGACCCCCGCAGAATCTGCACCC

>NC_008781|3|3|3525771-3525859|CRISPRCasFinder
TGCCCCCCGCAGAATCTGCACCC	CCCGCTACCGATTTGGGTACGCCACCCCCGCAAATTCACGTAC
TGACCCCCGCAGAATCTGCACCC

Protein	Signature genes	Signature genes Name	Protein_function
NC_008781.1\|WP_011802692.1\|3523535_3523949_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|225253
NC_008781.1\|WP_041376762.1\|3518285_3518477_+\|hypothetical-protein	unknown	unknown	unknown
NC_008781.1\|WP_011802701.1\|3530356_3530581_+\|AlpA-family-phage-regulatory-protein	unknown	unknown	gnl\|CDD\|225848
NC_008781.1\|WP_011802699.1\|3528682_3529627_+\|phage-Gp37/Gp68-family-protein	unknown	unknown	gnl\|CDD\|377854
NC_008781.1\|WP_011802700.1\|3529623_3529881_+\|hypothetical-protein	unknown	unknown	unknown
NC_008781.1\|WP_011802694.1\|3524921_3525419_+\|hypothetical-protein	unknown	unknown	unknown
NC_008781.1\|WP_041376765.1\|3528048_3528270_+\|hypothetical-protein	unknown	unknown	unknown
NC_008781.1\|WP_011802689.1\|3521741_3522446_+\|hypothetical-protein	unknown	unknown	unknown
NC_008781.1\|WP_041376766.1\|3529877_3530360_+\|hypothetical-protein	unknown	unknown	unknown
NC_008781.1\|WP_011802693.1\|3524304_3524925_+\|DUF1484-family-protein	unknown	unknown	gnl\|CDD\|284721
NC_008781.1\|WP_011802691.1\|3523121_3523514_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|225253
NC_008781.1\|WP_041376761.1\|3518051_3518246_+\|hypothetical-protein	unknown	unknown	unknown
NC_008781.1\|WP_011802687.1\|3518383_3518809_+\|ogr/Delta-like-zinc-finger-family-protein	unknown	unknown	gnl\|CDD\|368019
NC_008781.1\|WP_011802697.1\|3527711_3527978_+\|hypothetical-protein	unknown	unknown	unknown
NC_008781.1\|WP_011802696.1\|3526464_3527712_+\|hypothetical-protein	unknown	unknown	unknown
NC_008781.1\|WP_011802690.1\|3522467_3523019_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|371128
NC_008781.1\|WP_011802702.1\|3530588_3531785_-\|integrase-arm-type-DNA-binding-domain-containing-protein	unknown	unknown	gnl\|CDD\|271182
NC_008781.1\|WP_011802698.1\|3528269_3528686_+\|DUF2528-family-protein	unknown	unknown	gnl\|CDD\|371251
NC_008781.1\|WP_157040312.1\|3518568_3521694_+\|bifunctional-DNA-primase/helicase	unknown	unknown	gnl\|CDD\|379044
NC_008781.1\|WP_011802703.1\|3532054_3533389_-\|serine--tRNA-ligase	unknown	unknown	gnl\|CDD\|235461

Protein	Function_ID	Function_description	E-value
NC_008781.1\|WP_011802691.1\|3523121_3523514_-\|hypothetical-protein	gnl\|CDD\|225253	COG2378, COG2378, Predicted transcriptional regulator [Transcription].	1.13741e-05
NC_008781.1\|WP_011802692.1\|3523535_3523949_-\|hypothetical-protein	gnl\|CDD\|225253	COG2378, COG2378, Predicted transcriptional regulator [Transcription].	1.35885e-05
NC_008781.1\|WP_011802687.1\|3518383_3518809_+\|ogr/Delta-like-zinc-finger-family-protein	gnl\|CDD\|368019	pfam04606, Ogr_Delta, Ogr/Delta-like zinc finger. This is a viral family of phage zinc-binding transcriptional activators, which also contains cryptic members in some bacterial genomes. The P4 phage delta protein contains two such domains attached covalently, while the P2 phage Ogr proteins possess one domain but function as dimers. All the members of this family have the following consensus sequence: C-X(2)-C-X(3)-A-(X)2-R-X(15)-C-X(4)-C-X(3)-F. This family also includes zinc fingers in recombinase proteins.	6.42961e-14
NC_008781.1\|WP_011802693.1\|3524304_3524925_+\|DUF1484-family-protein	gnl\|CDD\|284721	pfam07363, DUF1484, Protein of unknown function (DUF1484). This family consists of several hypothetical bacterial proteins of around 110 residues in length. Members of this family appear to be found exclusively in Ralstonia solanacearum. The function of this family is unknown.	0.000312401
NC_008781.1\|WP_011802699.1\|3528682_3529627_+\|phage-Gp37/Gp68-family-protein	gnl\|CDD\|377854	pfam07505, DUF5131, Protein of unknown function (DUF5131). This is a family of bacterial and phage proteins of unknown function. There are three highly conserved cysteine residues in the disposition, Cx6Cxxc, amongst many highly conserved residues.	5.52867e-118
NC_008781.1\|WP_011802690.1\|3522467_3523019_+\|hypothetical-protein	gnl\|CDD\|371128	pfam10547, P22_AR_N, P22_AR N-terminal domain. This domain was identified by Iyer and colleagues.	2.31768e-54
NC_008781.1\|WP_011802698.1\|3528269_3528686_+\|DUF2528-family-protein	gnl\|CDD\|371251	pfam10800, DUF2528, Protein of unknown function (DUF2528). This family of proteins has no known function. Some of the sequences are annotated as ea10 however the function of this protein is unknown.	1.69487e-38
NC_008781.1\|WP_011802701.1\|3530356_3530581_+\|AlpA-family-phage-regulatory-protein	gnl\|CDD\|225848	COG3311, AlpA, Predicted transcriptional regulator [Transcription].	3.03113e-12
NC_008781.1\|WP_011802702.1\|3530588_3531785_-\|integrase-arm-type-DNA-binding-domain-containing-protein	gnl\|CDD\|271182	cd00801, INT_P4_C, Bacteriophage P4 integrase, C-terminal catalytic domain. P4-like integrases are found in temperate bacteriophages, integrative plasmids, pathogenicity and symbiosis islands, and other mobile genetic elements. The P4 integrase mediates integrative and excisive site-specific recombination between two sites, called attachment sites, located on the phage genome and the bacterial chromosome. The phage attachment site is often found adjacent to the integrase gene, while the host attachment sites are typically situated near tRNA genes. This family belongs to the superfamily of DNA breaking-rejoining enzymes, which share the same fold in their catalytic domain and the overall reaction mechanism. The catalytic domain contains six conserved active site residues. Their overall reaction mechanism involves cleavage of a single strand of a DNA duplex by nucleophilic attack of a conserved tyrosine to give a 3' phosphotyrosyl protein-DNA adduct. In the second rejoining step, a terminal 5' hydroxyl attacks the covalent adduct to release the enzyme and generate duplex DNA.	1.2772e-43
NC_008781.1\|WP_157040312.1\|3518568_3521694_+\|bifunctional-DNA-primase/helicase	gnl\|CDD\|379044	pfam13155, Toprim_2, Toprim-like. This is a family or Toprim-like proteins.	1.47198e-16
NC_008781.1\|WP_011802703.1\|3532054_3533389_-\|serine--tRNA-ligase	gnl\|CDD\|235461	PRK05431, PRK05431, seryl-tRNA synthetase; Provisional.	0

>NC_008781.1|WP_011802694.1|3524921_3525419_+|hypothetical-protein
MNGLKKPRRPRWPANRLAHESTVHKVTPFATEETAALSNEAHLAWHHLINGTGTKAHFDTLATSLNASLILSEPIGQAAIDVAVRAQQAMVSMQARFHRVGRFGADAQALADVPPGLDLYDQLLSFANPLQLVQAVCKSWKRIAAGDVLAPAYPAAAAVTAGAGA
>NC_008781.1|WP_011802693.1|3524304_3524925_+|DUF1484-family-protein
MANSSRAAAPRSAVAGSAAFPTQSAHRALMSLSDVRDAIENANNSLIALCELLDAANGARLSADHLHVLLAPVQQQLGRAFDDLNDMHLVEPTTDTLPVLDTAEPAPVQAVRPLASGEVLLRAPGKVTGRFFTINGDEALVMSDDNDFEIRLYRDYSNKNKRQKWNPAWWFSFESRQDMQGRNWSGNSSTYITDDFGNLVEIGGAA
>NC_008781.1|WP_011802692.1|3523535_3523949_-|hypothetical-protein
MAWYVWAGLVIFVLVAVVLMLGFVFADSGSTTPAQTYADVDRDGDDDENKDLLSEAGSLRISYVDEKGNSTERDISIYESGATNRKFQAYCSLRKDTRDFLFERIEYATDLDTGEVLSQADVFRRVHPGRKVPATLV
>NC_008781.1|WP_011802691.1|3523121_3523514_-|hypothetical-protein
MAWYEWLMIAVIFAAWQRLWFIKRRGQRSDFSKEGRHYEDAGDDGGNPSLHGKGKFRIRYTDADGQSTQRDITVQPFSSTPRKFSAHCHLRNATRTFIFDRIVQVIDLDTGEVLSNADFFRRVHKCSRLP
>NC_008781.1|WP_011802690.1|3522467_3523019_+|hypothetical-protein
MNEISPAPQLNGQLSVVLFNEDPLVLAEHNAQPYVVMRALVTAMGLTWQPQHAKLMEKFGSSVMEIVTIAEDGKPRAMVCLPLRKLPGWLYSINPGKVSEALRPKVLQYQQECDEVLWRHWTKQNPLHRGQKESRPDLVSLIKIRSITKHAGELMALNAMISDAYASLGYPLPADPQLKLQGI
>NC_008781.1|WP_011802689.1|3521741_3522446_+|hypothetical-protein
MSQSLATPDSVLPQPVGFINFQSSALIVMRHEGIEYIEVQPLNDLIGVHWKVTKFTAKGVDAHLYGTQSLPPPKIAGVVSSGTSASGIVCIRLDRAEMLLEHVADKLKKRGKVREAKNLRDLQAKWAEVKSEFSNKPLETRPDSITKAQPSTAPQTEITMRQISQPANPVFYGIDRCLSDADRTVMFTTPNPFIAAACDQSGQVCALEKPIEEPITAFEKEISDFKTAISSHPL
>NC_008781.1|WP_157040312.1|3518568_3521694_+|bifunctional-DNA-primase/helicase
MPQPAVPRKFCVPRRGNPLVNHSFQPQPPAQRPPVAHRAAPSAARCHQQPANRSPSRHRGNDHAGARQPDRHLFRTARTMIQNDLLSEISQRLQQEFEFKTHDKYLQQGKCPNCHKKSLWTYAATPWVIHCERLNNCGYESHVKDLYPELFNSWTERYQVPEQAKPVAEQNPNAAVDAYLATARGFDLSRIAGLYSQESYYDAKADQGRGAGTSTVRFAVADTWWERLIDRPWRFGKKKANFKFGGTYAGQWWAMPSLSFADQAPPPPPETAIADAMERAMQAASASGPAAPAVPAVPLAPPPAELWLVEGIFDAIALDHHDIAAVALLSCNNYPEKALEELDAQLKRQGGTVKAPVLVWALDGDKAGQDFTRKHVARARKAGWVCKAAQIPQKGKGKLDWNDLHQRDQLQEAQLKNYLYHGALLIAATAQDKALIIYNHSGKADFDLDHGNKLYWFKLDLERYRKAMEQLEKDIDDGHKPFMTDDEKRTVGLTESGTLQPIANCRPQALYYQRNEITQEAWYYFCVSFPHDGGDVKGTFTAGQLTAASEFKKQLLHMAPGAMFSGSSYQLEKIMQRQLENPKIVQTVDFIGYSAPHRTYILGKVAVRDGQIHEANAEDYFDIDKLAVKTLQKSIRLAVNTDAQDYDRTAWVQHLWNAFGAKGIVALTYWVGSLFAEQIREEHQSFPFLEIVGEPGSGKTTLIQFLWKLFGRDHEGLDPSKSTSAGRMRTFTQVSNLPIVLIESDRETKTGHQAHVKSFDWDELKDAYNGNSIRTTGVKTGGNETYDPPFRASIVISQNNPVSASQAIMERICHMTFNTQGFSPASYESAKSLEKIDIEHVSGFLLAALRREAVICQHIKDETDANIKFLLEQDGIHKPRIAKNHAQLLSIATALRSLVKITDEQFNQVRAQIVTMARERQQSINADHPLVTEFWEAFNYLDGLRPNSTTGFPDPRPLLNHSRQHDVIAVNLNEFVEKAAMHRQQIPVLADLKKVLRTSKLRRFMEAKPVNSAINIRVEAGHEVPKTVYCWLFEKPGQRKV
>NC_008781.1|WP_011802687.1|3518383_3518809_+|ogr/Delta-like-zinc-finger-family-protein
MAYQNPLAPVGKTNHRPRPRLVCRSPKGPSVRLHITCPNCESPAYGFRKRQLSTLVTELAYECRNPLCRASFVFQGEVTRWLTIPSNLNPQLNVPLSPIVQRRQQLDAINNLQTAVLPDIGEMITLERGSQIDIFSEQPEQ
>NC_008781.1|WP_041376762.1|3518285_3518477_+|hypothetical-protein
MPVHTLDLNDAERDVLERVRVSQGLQTIDQAAEWLIKTRLRQSAKQTTGRGRALYVVHPKARQ
>NC_008781.1|WP_041376761.1|3518051_3518246_+|hypothetical-protein
MYPDPKRIRSHRITVCLDEYEHDLLTALANYQGEPFSKLLRVLVMREAQQLLLGSGDSVEQSAA
>NC_008781.1|WP_011802696.1|3526464_3527712_+|hypothetical-protein
MNTPIHSSTSDSQHMPPAVYLAIMLIALALGADAVHVNREYAFANLGMLGLDAAALAVRKTSIDLLLLADIALFFVAAMMPRAKFGHLRCKLLVLGILIWAFDCAHTYQARIGIVMAGQSTAVATDQRSADLRASIDSLRATASGLRQSAARQSSSLIAASRADGSASLRQAIDADQRAQALSAELATSEHGKAPAEATIWGQWMPWKAFAESLLISMVGLVMFSLAGEMVRAARDACAARRTAIPVPAAKKSTALPRWSSAMPQPSPAYAAIAVPLGAMGAPLPTFVSVPVPPSISVPAVPTVRKQAQPAIEKHSTPPAKPSTASTVRSAKPDAGTAGKAAAARYQRIESAVIAGTLKPSVRSLQQAEGGGTLAARRYLEQLASEGVIERAGQGWALVAAGATAKESQLTLAGI
>NC_008781.1|WP_011802697.1|3527711_3527978_+|hypothetical-protein
MNQITMTGDDWTSDRDRKAQAQAIAARKKTAQELTAQLEKSVAAMQKFINACSACGDPKVLNADDGRQRLREQMQEYATYLDTVTWTK
>NC_008781.1|WP_041376765.1|3528048_3528270_+|hypothetical-protein
MMKIFKGMSEQPQETFSERLSEEDRTSASRLKAAQCVPERVCNSTSKTLYTGPAWSAARPGTDAIQHIKSRGF
>NC_008781.1|WP_011802698.1|3528269_3528686_+|DUF2528-family-protein
MSMIKTFKVCAEYNDEMFVVLQVDMDKLTPALANEVNDFWGGEQDRLSSEDDDVVRAVIRLYGSRLIRMMLSDGGATFTATRAPEAAQAWTVEMQSQEGWPGTDDTPSGLIGIQVIEAQVEVPDYDGVELSDITAWRS
>NC_008781.1|WP_011802699.1|3528682_3529627_+|phage-Gp37/Gp68-family-protein
MSANSKIEWTDHTFNGWEGCEKISPGCDNCYAEARNARFAGGVATNWGPGAERRRTSGANWNLPKRWNAQHAAFHAQHGRRQRVFCASLSDVFDNQIEKQWRDDLWQLIWETPHLDWQLLTKRIGNVMDMLPDEWGNGLTPYWPHVWIGATVVNQTEADRDIPKLIAVPAAKRFLSLEPLLGPVDLRLMSRSFGFPKHITRDGHAIGMPQGLHQVIVGGESGRAARPMHPEWARSLRDQCAYAGIPFLFKQWGEWISTDQEACPSGPPFSRWEWADGTAFQPGDGNRAMSLFCKAGKKSTGRLLDEITHDGFPA
>NC_008781.1|WP_011802700.1|3529623_3529881_+|hypothetical-protein
MTPQILLLVLEWGAAALTIYGAWLLANKGKHESWGFVLFLAANALWICFAWLQGHTGMLVQQLVLTAISLQGIRKGLIQPLKGIK
>NC_008781.1|WP_041376766.1|3529877_3530360_+|hypothetical-protein
MKHADFIATLDQSPANGPVILAWENSDGATVFASLPRQDVRQMLVDFKEQHLCSFDDQIQQEADLIDLVREYFRQTEDFDQSICTGGMSRHGDGAMPATAEQRRLINRNAIQARQALGEQAEQKGYTPAQLGDMLRRFNRHPYWIAEIVKSVSDARGVRR
>NC_008781.1|WP_011802701.1|3530356_3530581_+|AlpA-family-phage-regulatory-protein
MSHAVHAAPLIYRKKVVLEKFGISETTLRRWMQDEGFPRPKQLGPRAVGWVVDQVGAWLEKRPVALSNSLDDED
>NC_008781.1|WP_011802702.1|3530588_3531785_-|integrase-arm-type-DNA-binding-domain-containing-protein
MPKLPRELSPIEIGRLKSEGVYAVGGVPGLYLQIIGGSRAWVLRFVVGTRRRRMGLGGFPAVTLAQARDKARAARELMDQGIDPIQSREAVMHKAAAARARALTFSKASEQFIAAREAEWRNAKHRQQWENSLATYANPFIGEMAVSEIGQEDILKVLEPIWRTKTETASRVRGRIEQILDWAAVRGHRRGENPARWTGHLDKLLPKPSKIAKVEHHPAVEIGEAQAVVRRIEACAGMGARALLYQVLTATRSGEVRGTLWQEIDLDAGVWNIPESRMKAHKPHRVSLSKQAVQLLRLQPRFEDCELVFPSTKMTPLSDMSLTAVMRRLKLDAVPHGFRSTFSDWAAECTSYPRDLVEMALAHAIDSKVEAAYRRGDMLAKRAALMQAWADYCLPQPG
>NC_008781.1|WP_011802703.1|3532054_3533389_-|serine--tRNA-ligase
MLDINLLRKDLPSAIARLETRKSPQTFLNVEAFQTLEAERKAVQIRTEELQGQRGTLSKQIGQLKSKGEDASAVMALVSHSKAELESSAKRLEQIQTEMQALLLAVPNLPHDSVPQGIGEAGNVEVRKWSPFEGLGGEPAALSFEPRDHVDVGQPLGLDFELGTKLTGSRFTVMKGPLARLHRALSQFMLDVQTAEHGYTECYVPYIVNSDSLRGTGQLPKFEEDLFAARKGGQEGQAENAALYLIPTSEVPLTNFVRDEVVPEAQLPLKFTAHTPCFRSEAGSYGRDTRGMIRQHQFDKVEMVQVVHPEKSYEALEAMTGHAEVILQKLGLPYRVMLLCTGDMGFGATKTYDLEVWLPAQSTYREISSVSNCEAFQARRLQARFKNAQGKNEFVHTLNGSGLAVGRTLVAVLENYQRADGGVDIPAVLQPYMGGMTTLSLPAA

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

419900 : 443963

Bodo_saltans_virus(25.0%)

transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_086000529.1\|419900_420855_-\|transposase	IS630 family transposase	A0A2H4UV16	Bodo_saltans_virus	1.1e-09	21.9
WP_011799836.1\|421047_422730_-	phospholipase D family protein	NA	NA	NA	NA
WP_011799837.1\|422890_424816_-	ATP-binding cassette domain-containing protein	A0A2K9L3Z8	Tupanvirus	6.2e-49	29.8
WP_041376462.1\|431064_431376_-	hypothetical protein	NA	NA	NA	NA
WP_011798428.1\|431573_433643_+	serine recombinase	NA	NA	NA	NA
WP_011799840.1\|434613_435651_-\|transposase	IS630 family transposase	S5VXX4	Leptospira_phage	1.0e-34	34.6
WP_011799842.1\|436530_437613_-\|transposase	IS110 family transposase	NA	NA	NA	NA
WP_011799845.1\|439114_439402_-	IS66 family insertion sequence element accessory protein TnpB	NA	NA	NA	NA
WP_011799846.1\|439443_439854_-	IS66 family insertion sequence hypothetical protein	NA	NA	NA	NA
WP_011799847.1\|439930_441178_-\|transposase	IS5 family transposase	K4ICS3	Acidithiobacillus_phage	2.0e-48	41.7
WP_011799848.1\|441483_442551_+\|transposase	IS110 family transposase	NA	NA	NA	NA
WP_011799849.1\|442922_443963_+\|transposase	IS110 family transposase	NA	NA	NA	NA

DBSCAN-SWA_2

1437746 : 1482787

Escherichia_phage(25.0%)

tRNA,transposase,protease

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_011800757.1\|1437746_1439624_-\|tRNA	glutamine--tRNA ligase/YqeY domain fusion protein	A0A222YZ70	Escherichia_phage	7.4e-164	49.9
WP_011800758.1\|1439758_1440211_+	hypothetical protein	NA	NA	NA	NA
WP_011800759.1\|1440338_1440929_-	DUF3455 domain-containing protein	NA	NA	NA	NA
WP_011800760.1\|1441307_1442366_+	porin	NA	NA	NA	NA
WP_011800761.1\|1442520_1443168_-	DUF924 domain-containing protein	A0A1V0SIY0	Klosneuvirus	1.1e-18	32.4
WP_011800762.1\|1443278_1444112_+	undecaprenyl-diphosphate phosphatase	NA	NA	NA	NA
WP_011800763.1\|1444120_1444972_-	alpha/beta hydrolase	NA	NA	NA	NA
WP_011800764.1\|1445049_1445877_-\|protease	proteasome-type protease	NA	NA	NA	NA
WP_011800765.1\|1445916_1448529_-	DNA mismatch repair protein MutS	A0A1V0SDQ0	Indivirus	3.0e-22	23.1
WP_011800766.1\|1448697_1449588_-	DMT family transporter	NA	NA	NA	NA
WP_011800767.1\|1449678_1450593_+	LysR family transcriptional regulator	NA	NA	NA	NA
WP_011800768.1\|1450787_1451132_+	hypothetical protein	NA	NA	NA	NA
WP_011800769.1\|1451151_1451562_+	hypothetical protein	NA	NA	NA	NA
WP_011800770.1\|1452342_1453125_+	DUF2726 domain-containing protein	NA	NA	NA	NA
WP_011800771.1\|1453156_1455391_-	FUSC family protein	NA	NA	NA	NA
WP_011800772.1\|1455775_1456588_+	1-acyl-sn-glycerol-3-phosphate acyltransferase	NA	NA	NA	NA
WP_041376581.1\|1456625_1457414_+	glycosyltransferase family 2 protein	NA	NA	NA	NA
WP_011800774.1\|1457410_1458148_-	3-oxoacyl-ACP reductase FabG	M1NMS3	Moumouvirus	2.8e-05	35.4
WP_157040384.1\|1458144_1458669_-	3-hydroxylacyl-ACP dehydratase	NA	NA	NA	NA
WP_011800776.1\|1458668_1459505_-	3-oxoacyl-ACP synthase	NA	NA	NA	NA
WP_041376582.1\|1459536_1460730_-	beta-ketoacyl-[acyl-carrier-protein] synthase family protein	NA	NA	NA	NA
WP_011800778.1\|1460763_1461486_-	phosphatase PAP2 family protein	NA	NA	NA	NA
WP_011800779.1\|1461482_1462286_-	polysaccharide deacetylase family protein	NA	NA	NA	NA
WP_011800780.1\|1462278_1464615_-	MMPL family transporter	NA	NA	NA	NA
WP_011800781.1\|1464623_1465274_-	outer membrane lipoprotein carrier protein LolA	NA	NA	NA	NA
WP_011800782.1\|1465277_1466258_-	acyl-CoA synthetase	NA	NA	NA	NA
WP_011800783.1\|1467914_1468595_-	membrane protein	NA	NA	NA	NA
WP_011800784.1\|1468591_1468888_-	acyl carrier protein	NA	NA	NA	NA
WP_011800785.1\|1468972_1469965_-	inositol monophosphatase	NA	NA	NA	NA
WP_041376586.1\|1470134_1470962_+	RNA methyltransferase	NA	NA	NA	NA
WP_011800787.1\|1470971_1471751_+	serine O-acetyltransferase	NA	NA	NA	NA
WP_011800788.1\|1471831_1472431_-	molybdopterin adenylyltransferase	NA	NA	NA	NA
WP_086000537.1\|1472427_1473021_-	DUF615 domain-containing protein	NA	NA	NA	NA
WP_011800790.1\|1473042_1474452_+\|protease	metalloprotease PmbA	NA	NA	NA	NA
WP_157040225.1\|1474528_1475341_+	DUF4399 domain-containing protein	NA	NA	NA	NA
WP_011800792.1\|1475341_1475803_-\|tRNA	aspartyl-tRNA amidotransferase subunit B	NA	NA	NA	NA
WP_011484193.1\|1475925_1476138_-	30S ribosomal protein S21	NA	NA	NA	NA
WP_157040226.1\|1476253_1476418_-	hypothetical protein	NA	NA	NA	NA
WP_011800794.1\|1476393_1476699_+	type II toxin-antitoxin system HigB family toxin	A0A0P0ZE17	Stx2-converting_phage	1.2e-15	44.4
WP_157040385.1\|1476719_1477079_+	transcriptional regulator	A0A222YXG1	Escherichia_phage	3.6e-35	65.2
WP_011800796.1\|1477184_1477403_-	cell division protein FtsK	NA	NA	NA	NA
WP_011799840.1\|1477519_1478557_-\|transposase	IS630 family transposase	S5VXX4	Leptospira_phage	1.0e-34	34.6
WP_011800797.1\|1478822_1480103_+\|transposase	IS5 family transposase	K4ICS3	Acidithiobacillus_phage	2.7e-56	44.9
WP_011799848.1\|1480307_1481375_+\|transposase	IS110 family transposase	NA	NA	NA	NA
WP_011799849.1\|1481746_1482787_+\|transposase	IS110 family transposase	NA	NA	NA	NA

DBSCAN-SWA_3

1829251 : 1848971

Klebsiella_phage(33.33%)

tRNA,transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_011801124.1\|1829251_1830034_-\|tRNA	leucyl/phenylalanyl-tRNA--protein transferase	NA	NA	NA	NA
WP_011801125.1\|1830083_1830713_-	uracil phosphoribosyltransferase	NA	NA	NA	NA
WP_011801126.1\|1830751_1832269_-	DUF853 domain-containing protein	A0A248XCZ8	Klebsiella_phage	5.4e-80	43.5
WP_011801127.1\|1832363_1833089_+	YebC/PmpR family DNA-binding transcriptional regulator	NA	NA	NA	NA
WP_011801128.1\|1833127_1834420_+	phosphoribosylamine--glycine ligase	NA	NA	NA	NA
WP_011801129.1\|1834429_1835353_+	oxygen-dependent coproporphyrinogen oxidase	NA	NA	NA	NA
WP_011801130.1\|1835731_1836601_+	ribosome silencing factor	NA	NA	NA	NA
WP_011801131.1\|1836597_1837065_+	23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH	NA	NA	NA	NA
WP_011801132.1\|1837086_1837689_+	septum formation inhibitor Maf	NA	NA	NA	NA
WP_011801133.1\|1837707_1839207_+	ribonuclease G	NA	NA	NA	NA
WP_011801134.1\|1839226_1839976_+	polysaccharide deacetylase family protein	NA	NA	NA	NA
WP_011801135.1\|1839972_1841184_+	glycosyltransferase family 4 protein	NA	NA	NA	NA
WP_011801137.1\|1841485_1842523_-\|transposase	IS630 family transposase	S5VXX4	Leptospira_phage	2.3e-29	28.5
WP_011801138.1\|1842593_1843079_+\|transposase	transposase	NA	NA	NA	NA
WP_083758027.1\|1843075_1844368_+\|transposase	IS3 family transposase	NA	NA	NA	NA
WP_157040246.1\|1844069_1845624_+\|transposase	IS3 family transposase	A0A1B1P773	Bacillus_phage	6.8e-46	36.4
WP_011799961.1\|1846259_1847615_-\|transposase	IS701 family transposase	NA	NA	NA	NA
WP_011801141.1\|1847996_1848971_+\|transposase	IS1595-like element ISPna2 family transposase	NA	NA	NA	NA

DBSCAN-SWA_4

2398581 : 2407365

Pseudomonas_phage(66.67%)

protease,portal,tail

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_157040266.1\|2398581_2401284_-\|tail	phage tail tape measure protein	D9ZNE6	Clostridium_phage	5.5e-43	31.1
WP_011801635.1\|2401431_2402190_-	hypothetical protein	L7P7U8	Pseudomonas_phage	3.8e-10	28.3
WP_011801636.1\|2402221_2402641_-	hypothetical protein	NA	NA	NA	NA
WP_011801637.1\|2402641_2402950_-	hypothetical protein	NA	NA	NA	NA
WP_157040267.1\|2402988_2403354_-	DUF2190 family protein	A5LH31	Enterobacteria_phage	5.5e-07	34.4
WP_011801639.1\|2403418_2405443_-\|protease	Clp protease ClpP	A0A1W6JT88	Pseudomonas_phage	1.7e-118	45.2
WP_011801640.1\|2405541_2407131_-\|portal	phage portal protein	A0A1W6JTB6	Pseudomonas_phage	3.4e-101	42.7
WP_011801641.1\|2407140_2407365_-	hypothetical protein	A0A0A0YRQ0	Pseudomonas_phage	8.6e-11	62.3

DBSCAN-SWA_5

2425319 : 2432182

Gordonia_phage(16.67%)

integrase

attL 2419845:2419864|attR 2437541:2437560

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
2419845:2419864	attL	NA	NA	NA	NA
WP_011801669.1\|2425319_2426315_+\|integrase	site-specific integrase	A0A160DEV1	Gordonia_phage	3.0e-07	40.8
WP_011801670.1\|2426498_2427221_-	DNA polymerase III subunit epsilon	A0A1X9SH08	Bradyrhizobium_phage	6.4e-39	38.5
WP_011801671.1\|2427247_2427586_-	ISC system 2Fe-2S type ferredoxin	NA	NA	NA	NA
WP_011801672.1\|2427625_2429488_-	Fe-S protein assembly chaperone HscA	F2Y2E1	Organic_Lake_phycodnavirus	4.1e-98	39.7
WP_011801673.1\|2429519_2430038_-	Fe-S protein assembly co-chaperone HscB	NA	NA	NA	NA
WP_011801674.1\|2430135_2430459_-	iron-sulfur cluster assembly protein IscA	A0A2H4N7N5	Lake_Baikal_phage	2.9e-28	58.9
WP_011801675.1\|2430495_2430897_-	Fe-S cluster assembly scaffold IscU	A0A218MKD1	uncultured_virus	8.9e-51	77.6
WP_011801676.1\|2430964_2432182_-	IscS subfamily cysteine desulfurase	A0A2K9L2Y3	Tupanvirus	5.7e-08	20.9
2437541:2437560	attR	NA	NA	NA	NA

DBSCAN-SWA_6

3446077 : 3533389

Burkholderia_phage(31.58%)

tail,plate,terminase,head,protease,capsid,integrase,tRNA,portal

attL 3498566:3498582|attR 3535508:3535524

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_011802613.1\|3446077_3447043_+\|protease	trypsin-like serine protease	A0A1B1IRD3	uncultured_Mediterranean_phage	9.8e-11	29.3
WP_011802614.1\|3447055_3448075_+	MoxR family ATPase	NA	NA	NA	NA
WP_011802615.1\|3448191_3449178_+	DUF58 domain-containing protein	NA	NA	NA	NA
WP_011802616.1\|3449199_3450264_+	VWA domain-containing protein	NA	NA	NA	NA
WP_011802617.1\|3450400_3450598_-	hypothetical protein	NA	NA	NA	NA
WP_157040311.1\|3450651_3451782_-	patatin-like phospholipase family protein	NA	NA	NA	NA
WP_011802619.1\|3451884_3453219_-	hypothetical protein	NA	NA	NA	NA
WP_011802620.1\|3453254_3454007_-	hypothetical protein	NA	NA	NA	NA
WP_041377367.1\|3454055_3454637_-	hypothetical protein	NA	NA	NA	NA
WP_011802622.1\|3454694_3454970_-	J domain-containing protein	A0A1V0SIM1	Klosneuvirus	5.8e-09	45.3
WP_011802623.1\|3455259_3455757_+	hypothetical protein	NA	NA	NA	NA
WP_049763775.1\|3455850_3456579_-	lipoprotein-releasing ABC transporter ATP-binding protein LolD	G9BWD6	Planktothrix_phage	2.6e-32	41.0
WP_011802625.1\|3456799_3458056_-	lipoprotein-releasing ABC transporter permease subunit	NA	NA	NA	NA
WP_049763704.1\|3458090_3459065_+	hypothetical protein	NA	NA	NA	NA
WP_011802627.1\|3459111_3460854_+	single-stranded-DNA-specific exonuclease RecJ	A0A0R6PDC6	Moraxella_phage	5.1e-26	30.4
WP_011802628.1\|3461142_3462267_-	hypothetical protein	NA	NA	NA	NA
WP_011802629.1\|3462299_3462698_-	hypothetical protein	NA	NA	NA	NA
WP_011802630.1\|3462747_3465753_-	hypothetical protein	NA	NA	NA	NA
WP_011802631.1\|3465900_3467301_-	Fic family protein	NA	NA	NA	NA
WP_011802632.1\|3467480_3469133_-	exonuclease	NA	NA	NA	NA
WP_049763705.1\|3469135_3470395_-	hypothetical protein	NA	NA	NA	NA
WP_011802634.1\|3470541_3470772_-	hypothetical protein	NA	NA	NA	NA
WP_011802635.1\|3470807_3471476_+	Crp/Fnr family transcriptional regulator	NA	NA	NA	NA
WP_011802636.1\|3471578_3471770_+	DUF2892 domain-containing protein	NA	NA	NA	NA
WP_011802637.1\|3471911_3473015_+	ABC transporter ATP-binding protein	G3M9Y6	Bacillus_virus	1.2e-25	38.7
WP_011802638.1\|3473085_3474375_+	extracellular solute-binding protein	NA	NA	NA	NA
WP_011802639.1\|3474401_3475316_+	ABC transporter permease	NA	NA	NA	NA
WP_011802640.1\|3475318_3476203_+	ABC transporter permease subunit	NA	NA	NA	NA
WP_011802641.1\|3476199_3476910_+	GntR family transcriptional regulator	NA	NA	NA	NA
WP_011802642.1\|3476918_3477674_+	Asp/Glu racemase	NA	NA	NA	NA
WP_011802643.1\|3477742_3478606_+	PHP domain-containing protein	NA	NA	NA	NA
WP_011802644.1\|3478602_3479508_+	DMT family transporter	NA	NA	NA	NA
WP_011802645.1\|3479518_3480154_+	threonylcarbamoyl-AMP synthase	NA	NA	NA	NA
WP_011802646.1\|3480187_3480856_+\|protease	site-2 protease family protein	NA	NA	NA	NA
WP_011802647.1\|3480891_3482211_+\|tRNA	tryptophan--tRNA ligase	NA	NA	NA	NA
WP_011802648.1\|3482290_3482476_-	CsbD family protein	NA	NA	NA	NA
WP_011802649.1\|3482573_3483314_-	response regulator transcription factor	W8CYM9	Bacillus_phage	9.8e-27	35.1
WP_011802650.1\|3483310_3485353_-	PAS domain-containing protein	NA	NA	NA	NA
WP_011802651.1\|3485534_3487175_+	acyl-CoA synthetase	A0A2H4PQU7	Staphylococcus_phage	5.0e-31	25.9
WP_011802652.1\|3487297_3488983_+	electron transfer flavoprotein-ubiquinone oxidoreductase	NA	NA	NA	NA
WP_011802653.1\|3489027_3489504_+	MaoC family dehydratase	NA	NA	NA	NA
WP_011802654.1\|3489540_3491322_+	acyl-CoA dehydrogenase	NA	NA	NA	NA
WP_041377372.1\|3491403_3491709_+	DUF485 domain-containing protein	NA	NA	NA	NA
WP_011802656.1\|3491705_3493382_+	cation acetate symporter	NA	NA	NA	NA
WP_041376758.1\|3493789_3493993_+	hypothetical protein	NA	NA	NA	NA
WP_011802657.1\|3494948_3495995_-\|portal	phage portal protein	E5E3X1	Burkholderia_phage	5.3e-135	68.2
WP_011802658.1\|3495994_3497785_-\|terminase	terminase ATPase subunit family protein	E5FFI8	Burkholderia_phage	1.0e-231	67.3
WP_041377374.1\|3497919_3498771_+\|capsid	GPO family capsid scaffolding protein	E5FFI7	Burkholderia_phage	2.9e-59	46.6
3498566:3498582	attL	NA	NA	NA	NA
WP_011802660.1\|3498820_3499828_+\|capsid	phage major capsid protein, P2 family	E5FFI6	Burkholderia_phage	6.2e-109	59.1
WP_011802661.1\|3499833_3500616_+\|terminase	phage small terminase subunit	A0A077K804	Ralstonia_phage	1.4e-44	48.7
WP_011802662.1\|3500646_3501111_+\|head	head completion/stabilization protein	E5E3S2	Burkholderia_phage	2.8e-32	50.6
WP_011802663.1\|3501110_3501317_+\|tail	tail protein	E5E3S0	Burkholderia_phage	3.8e-13	58.6
WP_011802664.1\|3501320_3501539_+	hypothetical protein	NA	NA	NA	NA
WP_011802665.1\|3501535_3502048_+	glycoside hydrolase family protein	I6NW41	Burkholderia_virus	4.1e-48	59.2
WP_011802666.1\|3502044_3502551_+	phage protein	NA	NA	NA	NA
WP_011802667.1\|3502552_3502981_+\|tail	phage tail protein	A0A2H4J906	uncultured_Caudovirales_phage	4.6e-29	47.8
WP_011802668.1\|3502984_3503452_+	phage virion morphogenesis protein	K4NZQ8	Burkholderia_phage	1.9e-36	53.2
WP_011802669.1\|3503524_3504178_+\|plate	phage baseplate assembly protein V	A0A2H4JFJ8	uncultured_Caudovirales_phage	1.4e-37	42.7
WP_041377376.1\|3504183_3504546_+\|plate	baseplate assembly protein	A0A2H4JE52	uncultured_Caudovirales_phage	1.4e-31	59.8
WP_011802671.1\|3504542_3505430_+\|plate	baseplate assembly protein	A0A193GYM8	Enterobacter_phage	2.5e-77	54.1
WP_011802672.1\|3505422_3506100_+\|tail	phage tail protein I	D5LGZ2	Escherichia_phage	1.5e-37	46.0
WP_011802673.1\|3506106_3507903_+	hypothetical protein	D4P7M1	Rhodococcus_phage	3.4e-25	28.6
WP_011802674.1\|3507907_3508645_+	hypothetical protein	NA	NA	NA	NA
WP_011802675.1\|3508783_3510235_+\|tail	tail protein	A0A193GYM0	Enterobacter_phage	1.5e-124	51.4
WP_011802676.1\|3510240_3510531_+	hypothetical protein	A0A193GYZ3	Enterobacter_phage	1.3e-19	58.9
WP_011802677.1\|3510543_3511719_+\|tail	phage tail sheath protein	A0A2H4JCP8	uncultured_Caudovirales_phage	4.2e-149	67.8
WP_011802678.1\|3511744_3512257_+\|tail	phage major tail tube protein	E5FFG8	Burkholderia_phage	3.2e-53	57.4
WP_011802679.1\|3512318_3512561_+	hypothetical protein	NA	NA	NA	NA
WP_011802680.1\|3512592_3512949_+\|tail	phage tail assembly protein	A4PE51	Ralstonia_virus	2.8e-11	56.7
WP_011802681.1\|3512957_3513074_+\|tail	GpE family phage tail protein	E5E3Q0	Burkholderia_phage	3.9e-07	68.6
WP_011802682.1\|3513108_3515700_+\|tail	phage tail tape measure protein	A0A2H4JGB2	uncultured_Caudovirales_phage	1.3e-118	40.4
WP_011802683.1\|3515720_3516170_+\|tail	phage tail protein	A0A2H4JG54	uncultured_Caudovirales_phage	9.4e-41	56.4
WP_011802684.1\|3516175_3517210_+	phage late control D family protein	E5E3U4	Burkholderia_phage	1.8e-82	51.6
WP_011802685.1\|3517326_3517707_-	transcriptional regulator	E5E3P4	Burkholderia_phage	3.6e-09	34.2
WP_041376760.1\|3517791_3517989_+	hypothetical protein	NA	NA	NA	NA
WP_041376761.1\|3518051_3518246_+	hypothetical protein	NA	NA	NA	NA
WP_041376762.1\|3518285_3518477_+	hypothetical protein	E5E3T9	Burkholderia_phage	8.1e-10	56.1
WP_011802687.1\|3518383_3518809_+	ogr/Delta-like zinc finger family protein	NA	NA	NA	NA
WP_157040312.1\|3518568_3521694_+	bifunctional DNA primase/helicase	A0A077K8T2	Ralstonia_phage	2.6e-246	46.9
WP_011802689.1\|3521741_3522446_+	hypothetical protein	NA	NA	NA	NA
WP_011802690.1\|3522467_3523019_+	hypothetical protein	A0A0N7KZV8	Escherichia_phage	4.1e-30	55.5
WP_011802691.1\|3523121_3523514_-	hypothetical protein	NA	NA	NA	NA
WP_011802692.1\|3523535_3523949_-	hypothetical protein	NA	NA	NA	NA
WP_011802693.1\|3524304_3524925_+	DUF1484 family protein	NA	NA	NA	NA
WP_011802694.1\|3524921_3525419_+	hypothetical protein	NA	NA	NA	NA
WP_011802695.1\|3525415_3526450_+	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_011802696.1\|3526464_3527712_+	hypothetical protein	NA	NA	NA	NA
WP_011802697.1\|3527711_3527978_+	hypothetical protein	NA	NA	NA	NA
WP_041376765.1\|3528048_3528270_+	hypothetical protein	NA	NA	NA	NA
WP_011802698.1\|3528269_3528686_+	DUF2528 family protein	NA	NA	NA	NA
WP_011802699.1\|3528682_3529627_+	phage Gp37/Gp68 family protein	Q8W6R4	Burkholderia_virus	2.7e-106	60.2
WP_011802700.1\|3529623_3529881_+	hypothetical protein	NA	NA	NA	NA
WP_041376766.1\|3529877_3530360_+	hypothetical protein	NA	NA	NA	NA
WP_011802701.1\|3530356_3530581_+	AlpA family phage regulatory protein	NA	NA	NA	NA
WP_011802702.1\|3530588_3531785_-\|integrase	integrase arm-type DNA-binding domain-containing protein	A0A077KET4	Ralstonia_phage	1.2e-90	47.1
WP_011802703.1\|3532054_3533389_-\|tRNA	serine--tRNA ligase	A0A1B1IVT2	uncultured_Mediterranean_phage	9.8e-94	51.8
3535508:3535524	attR	NA	NA	NA	NA

DBSCAN-SWA_7

3881982 : 3890048

Acinetobacter_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_011799636.1\|3881982_3883173_-	elongation factor Tu	A0A1V0SLW6	Klosneuvirus	7.6e-13	28.3
WP_011803010.1\|3883840_3884578_-	uracil-DNA glycosylase	A0A0B5IW78	Pandoravirus	3.7e-50	48.1
WP_011803011.1\|3884592_3885384_-	indole-3-glycerol phosphate synthase TrpC	A0A0P0IR83	Acinetobacter_phage	3.0e-66	52.5
WP_041376800.1\|3885439_3886486_-	anthranilate phosphoribosyltransferase	A0A0N7IRD9	Acinetobacter_phage	4.5e-78	47.3
WP_011803013.1\|3886535_3887585_-	low-specificity L-threonine aldolase	NA	NA	NA	NA
WP_011803014.1\|3887642_3888227_-	aminodeoxychorismate/anthranilate synthase component II	A0A0P0IKJ1	Acinetobacter_phage	2.7e-64	59.8
WP_011803015.1\|3888230_3888545_-	chorismate mutase	NA	NA	NA	NA
WP_011803016.1\|3888548_3890048_-	anthranilate synthase component I	A0A0B5J984	Pandoravirus	3.7e-33	28.8

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

5. NC_008762

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

0 : 5972

Moraxella_phage(66.67%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_011798588.1\|1045_1798_-	hypothetical protein	A0A0R6PKK0	Moraxella_phage	2.1e-16	31.8
WP_011798589.1\|1797_2982_-	DUF262 domain-containing protein	A0A0R6PKN1	Moraxella_phage	4.2e-72	42.5
WP_041377832.1\|3009_3705_-	S24 family peptidase	NA	NA	NA	NA
WP_011798591.1\|3997_4507_-	hypothetical protein	NA	NA	NA	NA
WP_011798592.1\|4500_4917_-	hypothetical protein	NA	NA	NA	NA
WP_157040569.1\|4913_5084_-	hypothetical protein	NA	NA	NA	NA
WP_011798593.1\|5112_5346_-	hypothetical protein	NA	NA	NA	NA
WP_011798594.1\|5342_5972_-	AAA family ATPase	B0ZSI1	Halomonas_phage	2.1e-38	41.1

DBSCAN-SWA_2

13195 : 20820

Leptospira_phage(25.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_011798601.1\|13195_16660_-	class I SAM-dependent DNA methyltransferase	Q6NE04	Leptospira_phage	1.3e-20	22.4
WP_157040571.1\|17279_18167_-	plasmid replication initiator-like protein	A0A0K1Y6J9	Rhodobacter_phage	9.5e-45	38.7
WP_011798603.1\|18289_18595_-	type II toxin-antitoxin system RelE/ParE family toxin	NA	NA	NA	NA
WP_011798604.1\|18572_19037_-	hypothetical protein	NA	NA	NA	NA
WP_011798605.1\|19166_19736_-	recombinase family protein	E5FFF9	Burkholderia_phage	2.0e-51	59.3
WP_011798606.1\|20106_20820_-	DNA helicase	A0A0R8V1H3	Thermobifida_phage	8.3e-07	25.8

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage