CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NC_009079	Burkholderia mallei NCTC 10247 chromosome II, complete sequence	3 crisprs	csa3,cas3	0	0	5	0
NC_009080	Burkholderia mallei NCTC 10247 chromosome I, complete sequence	0 crisprs	csa3,DEDDh,DinG,WYL,cas3	0	0	11	0

Results visualization

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CRISPR-Cas detection and classification

Crispr_ID: NC_009079_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_009079_1

125630-125722

Orphan

Consensus_repeat	Method
TCGCCGCCGCGCGCGACGACGCGC	CRISPRCasFinder

1 spacers

The CRISPR arrays of NC_009079_1

>merge|NC_009079|1|125630-125722|CRISPRCasFinder
TCGCCGCCGCGCGCGACGACGCGCTGAAGGACGCGCTCGCGCAGGCCGCCGCCGAGCGCGAGCGGCTGATCGCCGCCGCGCGCGCCGACGCGC

>NC_009079|1|1|125630-125722|CRISPRCasFinder
TCGCCGCCGCGCGCGACGACGCGC	TGAAGGACGCGCTCGCGCAGGCCGCCGCCGAGCGCGAGCGGCTGA
TCGCCGCCGCGCGCGCCGACGCGC

Protein	Signature genes	Signature genes Name	Protein_function
NC_009079.1\|WP_004187346.1\|124464_125166_+\|F0F1-ATP-synthase-subunit-A	unknown	unknown	gnl\|CDD\|237383
NC_009079.1\|WP_004188073.1\|121629_123234_+\|F0F1-ATP-synthase-subunit-beta	unknown	unknown	gnl\|CDD\|183615
NC_009079.1\|WP_004188303.1\|128166_129015_+\|F0F1-ATP-synthase-subunit-gamma	unknown	unknown	gnl\|CDD\|376304
NC_009079.1\|WP_004203331.1\|136963_140203_-\|ATP-binding-cassette-domain-containing-protein	unknown	unknown	gnl\|CDD\|224054
NC_009079.1\|WP_004188355.1\|126157_128170_+\|F0F1-ATP-synthase-subunit-alpha	unknown	unknown	gnl\|CDD\|183987
NC_009079.1\|WP_044302747.1\|131903_133508_+\|methyl-accepting-chemotaxis-protein	unknown	unknown	gnl\|CDD\|185008
NC_009079.1\|WP_004188840.1\|119475_121269_-\|alpha/beta-fold-hydrolase	unknown	unknown	gnl\|CDD\|213656
NC_009079.1\|WP_004188458.1\|116886_118065_-\|acetate/propionate-family-kinase	unknown	unknown	gnl\|CDD\|235922
NC_009079.1\|WP_004188438.1\|123675_124167_+\|AtpZ/AtpI-family-protein	unknown	unknown	gnl\|CDD\|378198
NC_009079.1\|WP_004198323.1\|133599_133758_-\|hypothetical-protein	unknown	unknown	unknown
NC_009079.1\|WP_004188221.1\|123223_123679_+\|F0F1-ATP-synthase-subunit-epsilon	unknown	unknown	gnl\|CDD\|184057
NC_009079.1\|WP_004187158.1\|130892_131402_-\|hypothetical-protein	unknown	unknown	unknown
NC_009079.1\|WP_011204278.1\|118061_119492_-\|bifunctional-enoyl-CoA-hydratase/phosphate-acetyltransferase	unknown	unknown	gnl\|CDD\|236180
NC_009079.1\|WP_004188525.1\|135836_136961_-\|ABC-transporter-permease	unknown	unknown	gnl\|CDD\|223912
NC_009079.1\|WP_004198321.1\|129229_130255_+\|alcohol-dehydrogenase-AdhP	unknown	unknown	gnl\|CDD\|176257
NC_009079.1\|WP_011857754.1\|133851_135687_-\|response-regulator	unknown	unknown	gnl\|CDD\|237425
NC_009079.1\|WP_004201694.1\|124159_124468_+\|membrane-protein	unknown	unknown	gnl\|CDD\|274462
NC_009079.1\|WP_004187423.1\|121400_121658_-\|hypothetical-protein	unknown	unknown	unknown
NC_009079.1\|WP_004198322.1\|130331_130835_+\|hypothetical-protein	unknown	unknown	unknown
NC_009079.1\|WP_004187193.1\|125162_125411_+\|F0F1-ATP-synthase-subunit-C	unknown	unknown	gnl\|CDD\|184067

Protein	Function_ID	Function_description	E-value
NC_009079.1\|WP_004187346.1\|124464_125166_+\|F0F1-ATP-synthase-subunit-A	gnl\|CDD\|237383	PRK13421, PRK13421, F0F1 ATP synthase subunit A; Provisional.	1.54059e-122
NC_009079.1\|WP_004188073.1\|121629_123234_+\|F0F1-ATP-synthase-subunit-beta	gnl\|CDD\|183615	PRK12597, PRK12597, F0F1 ATP synthase subunit beta; Provisional.	0
NC_009079.1\|WP_004188303.1\|128166_129015_+\|F0F1-ATP-synthase-subunit-gamma	gnl\|CDD\|376304	pfam00231, ATP-synt, ATP synthase.	1.10329e-32
NC_009079.1\|WP_004203331.1\|136963_140203_-\|ATP-binding-cassette-domain-containing-protein	gnl\|CDD\|224054	COG1131, CcmA, ABC-type multidrug transport system, ATPase component [Defense mechanisms].	1.86967e-92
NC_009079.1\|WP_004188355.1\|126157_128170_+\|F0F1-ATP-synthase-subunit-alpha	gnl\|CDD\|183987	PRK13343, PRK13343, F0F1 ATP synthase subunit alpha; Provisional.	0
NC_009079.1\|WP_044302747.1\|131903_133508_+\|methyl-accepting-chemotaxis-protein	gnl\|CDD\|185008	PRK15048, PRK15048, methyl-accepting chemotaxis protein II; Provisional.	2.56608e-79
NC_009079.1\|WP_004188840.1\|119475_121269_-\|alpha/beta-fold-hydrolase	gnl\|CDD\|213656	TIGR01838, Poly-beta-hydroxybutyrate_polymerase, poly(R)-hydroxyalkanoic acid synthase, class I. This model represents the class I subfamily of poly(R)-hydroxyalkanoate synthases, which polymerizes hydroxyacyl-CoAs with three to five carbons in the hydroxyacyl backbone into aliphatic esters termed poly(R)-hydroxyalkanoic acids. These polymers accumulate as carbon and energy storage inclusions in many species and can amount to 90 percent of the dry weight of cell. [Fatty acid and phospholipid metabolism, Biosynthesis].	6.3979e-179
NC_009079.1\|WP_004188458.1\|116886_118065_-\|acetate/propionate-family-kinase	gnl\|CDD\|235922	PRK07058, PRK07058, acetate/propionate family kinase.	0
NC_009079.1\|WP_004188438.1\|123675_124167_+\|AtpZ/AtpI-family-protein	gnl\|CDD\|378198	pfam09527, ATPase_gene1, Putative F0F1-ATPase subunit Ca2+/Mg2+ transporter. This model represents a protein found encoded in F1F0-ATPase operons in several genomes, including Methanosarcina barkeri (archaeal) and Chlorobium tepidum (bacterial). It is a small protein (about 100 amino acids) with long hydrophobic stretches and is presumed to be a subunit of the enzyme. It carries two transmembrane helices and is a magnesium or calcium uniporter. The atp operon of alkaliphilic Bacillus pseudofirmus OF4, as in most prokaryotes, contains the eight structural genes for the F-ATPase (ATP synthase), which are preceded by an atpI gene that encodes a membrane protein with 2 TMSs. A tenth gene, atpZ, has been found in this operon, which is upstream of and overlapping with atpI.	7.77353e-17
NC_009079.1\|WP_004188221.1\|123223_123679_+\|F0F1-ATP-synthase-subunit-epsilon	gnl\|CDD\|184057	PRK13447, PRK13447, F0F1 ATP synthase subunit epsilon; Provisional.	4.44077e-63
NC_009079.1\|WP_011204278.1\|118061_119492_-\|bifunctional-enoyl-CoA-hydratase/phosphate-acetyltransferase	gnl\|CDD\|236180	PRK08190, PRK08190, bifunctional enoyl-CoA hydratase/phosphate acetyltransferase; Validated.	0
NC_009079.1\|WP_004198321.1\|129229_130255_+\|alcohol-dehydrogenase-AdhP	gnl\|CDD\|176257	cd08297, CAD3, Cinnamyl alcohol dehydrogenases (CAD). These alcohol dehydrogenases are related to the cinnamyl alcohol dehydrogenases (CAD), members of the medium chain dehydrogenase/reductase family. NAD(P)(H)-dependent oxidoreductases are the major enzymes in the interconversion of alcohols and aldehydes, or ketones. Cinnamyl alcohol dehydrogenases (CAD) reduce cinnamaldehydes to cinnamyl alcohols in the last step of monolignal metabolism in plant cells walls. CAD binds 2 zinc ions and is NADPH- dependent. CAD family members are also found in non-plant species, e.g. in yeast where they have an aldehyde reductase activity. The medium chain dehydrogenases/reductase (MDR)/zinc-dependent alcohol dehydrogenase-like family, which contains the zinc-dependent alcohol dehydrogenase (ADH-Zn) and related proteins, is a diverse group of proteins related to the first identified member, class I mammalian ADH. MDRs display a broad range of activities and are distinguished from the smaller short chain dehydrogenases (~ 250 amino acids vs. the ~ 350 amino acids of the MDR). The MDR proteins have 2 domains: a C-terminal NAD(P) binding-Rossmann fold domain of a beta-alpha form and an N-terminal catalytic domain with distant homology to GroES. The MDR group contains a host of activities, including the founding alcohol dehydrogenase (ADH), quinone reductase, sorbitol dehydrogenase, formaldehyde dehydrogenase, butanediol DH, ketose reductase, cinnamyl reductase, and numerous others. The zinc-dependent alcohol dehydrogenases (ADHs) catalyze the NAD(P)(H)-dependent interconversion of alcohols to aldehydes or ketones. Active site zinc has a catalytic role, while structural zinc aids in stability. ADH-like proteins typically form dimers (typically higher plants, mammals) or tetramers (yeast, bacteria), and generally have 2 tightly bound zinc atoms per subunit. The active site zinc is coordinated by a histidine, two cysteines, and a water molecule. The second zinc seems to play a structural role, affects subunit interactions, and is typically coordinated by 4 cysteines.	0
NC_009079.1\|WP_011857754.1\|133851_135687_-\|response-regulator	gnl\|CDD\|237425	PRK13557, PRK13557, histidine kinase; Provisional.	6.45347e-133
NC_009079.1\|WP_004201694.1\|124159_124468_+\|membrane-protein	gnl\|CDD\|274462	TIGR03165, F1F0_chp_2, F1/F0 ATPase, Methanosarcina type, subunit 2. Members of this protein family are uncharacterized, highly hydrophobic proteins encoded in the middle of apparent F1/F0 ATPase operons. We note, however, that this protein is both broadly and sparsely distributed. It is found in about only about two percent of microbial genomes sequenced, with the first ten examples found coming from the Euryarchaeota, Chlorobia, Betaproteobacteria, Deltaproteobacteria, and Planctomycetes. In most of these species, surrounding operon appears to represent a second F1/F0 ATPase system, and the member proteins belong to subfamilies with the same phylogenetic distribution as the current protein family.	3.23546e-10
NC_009079.1\|WP_004188525.1\|135836_136961_-\|ABC-transporter-permease	gnl\|CDD\|223912	COG0842, COG0842, ABC-type multidrug transport system, permease component [Defense mechanisms].	6.54035e-26
NC_009079.1\|WP_004187193.1\|125162_125411_+\|F0F1-ATP-synthase-subunit-C	gnl\|CDD\|184067	PRK13468, PRK13468, F0F1 ATP synthase subunit C; Provisional.	4.45015e-37

>NC_009079.1|WP_004187193.1|125162_125411_+|F0F1-ATP-synthase-subunit-C
MNNLIEVVSIAAAALAVSFGAIGPALAEGRAVGAAMDAIARQPDASGTVSRTLFVGLAMIETMAIYCLVVALLLLFANPFVK
>NC_009079.1|WP_004187346.1|124464_125166_+|F0F1-ATP-synthase-subunit-A
MNASPLSTVPLFSVGPVGISAPVLATWAIMAVLVALALVARRRLSVDAPSRLQSVLELFVATVDAQIADTMQTPPARYRALIGTIFVLVFCANGASLVPGVEPPTAHLETDAALALVVLAATLYYGVRARGVRGYLATFAEPTWVMIPLNVVEQLTRTFSLIVRLFGNVMSGVFVIGIVLSLAGLFVPIPLMALDLLTGTVQAYIFMVLSMVFIGAAVSGDETSAPRRGQENT
>NC_009079.1|WP_004201694.1|124159_124468_+|membrane-protein
MIEMWETARASFDGIAAAIGLALGFAAGACHFVSLGWNSRLFVAGRAGVALALQFARVALAVAVLVVLARAGFGMLVAGSAGFFAARAIAVRRAAALTGARR
>NC_009079.1|WP_004188438.1|123675_124167_+|AtpZ/AtpI-family-protein
MMKRRPPEVKREARDDAARGDARHAGAGAAPDDPRGAARRDPSPGSRAARGGATHPAARAAEPAAPKPAADRVERAAHTAAARAARGARDPEPSLGRRLAQIGVLGWTIVAPTLAALALGRWLDRMFATRVFFSAPLLMLGAALGLWLAWRWMKAQQHGDRDD
>NC_009079.1|WP_004188221.1|123223_123679_+|F0F1-ATP-synthase-subunit-epsilon
MGAELRVTIATPARVCVDDLPIVSLRAEDASGAFGIRAGHVDFVTLLRASVVRWRTADGATHYAALDGGVLRVTRGARIEIACRDAVLGESLAELEAVVRGVRATQLDEKRRARVDETRLHAQAVRRLLTYLRPEHAKDGVHAPLKPETLE
>NC_009079.1|WP_004188073.1|121629_123234_+|F0F1-ATP-synthase-subunit-beta
MADPQATNGTGAVCAERDASDVGDVSDVGDARDEGAGRVVAVRGAVVDVAFDGGALPALNEALTIPVDGAAPILAEVHAHLSDAAVRALALGPTGGLRRGAAVRATGGPIRVPVGDAVLGRLLSVTGAPGDDGAALAADVERRPIHRGAPLLAEQKSANALFATGIKVIDLLAPLAQGGKAAMFGGAGVGKTVFVMELIHAMVERYRGISVFAGIGERSREGHEMLLDMRGSGVLGRTVLVYGQMNEPPGARWRVPLTALAIAEYFRDERAQNVLLLMDNVFRFVQAGAEVSGLLGRLPSRVGYQPTLASEVAALQERIASVEGAAVTAIEAVYVPADDFTDPAVTAIAAHVDSMVVLSRAMAAEGMYPAIDPVASSSILLDPLVVGEAHVEVAIEVRRVIEHYRELQDVIALLGIDELGADDRRLVGRARRLQRFLTQPFAVTEAFTGQAGASVEIADTIAGCRAILRGDCDDWRESSLYMVGTLDDARRKEAAAREADARREAAAAASGAGPGTTSDPASGSAEPQGARHGR
>NC_009079.1|WP_004187423.1|121400_121658_-|hypothetical-protein
MPFVACGSATVAPVWLVRRWLHHNGARRPPADLGQETGNRQTKRGIAQSETIDASASGADKVRAASIVDSNQIPQTYAWLQWPCQ
>NC_009079.1|WP_004188840.1|119475_121269_-|alpha/beta-fold-hydrolase
MDTRHAPESGAPDAPLPAHPPASYAPESPYRIFDLAKEASVAKLTSGLSPASLQLALADWLIHLAAAPGKRAELATLALRHAALLGQYLLEAATGRTPAAPAQPSPGDRRFRAGAWQLEPYRFWHQSFLLAEQWWRAATRDVPGVSPHHEDVVAFSARQMLDTFAPANYVATNPEIAQRTALTGGANLAQGVWNYLDDVRRLITKQPPAGAEQFELGRNLATTPGRVVFRNHLIELLQYSPTTPDVYAQPVLIVPAWIMKYYILDLSAHNSLIRYLVGEGHTVFCISWRNVDASDRDLSLDDYRKLGVMDALDTIGAIVPGEKIHATGYCLGGTLLSIAAAAMANTGDDRLASITLLAAQTDFAEPGELQLFIDDSEIHFLESMMWERGYLGAHQMAGSFQLLMSNDLIWSRVIHDYLLGERTPMIDLMAWNADSTRMPYRMHSEYLRHLFLDNDLATNRYVIDGQTVSVHNIRAPFFVVGTEHDHIAPWRSVYKIHYLSGSDVTFVLTAGGHNAGIVSEPGHAKRHYRMKMTAAAAPSISPDEWLAGATDFEGSWWPAWHAWLARHSSPQRVAPPPLGKPGAHTLGDAPGTYVFQK
>NC_009079.1|WP_011204278.1|118061_119492_-|bifunctional-enoyl-CoA-hydratase/phosphate-acetyltransferase
MCSRNKECRVDREILQNRPFDSLAIGDSASLVRTASRDDIDLFAAMSGDVNPAHLDAAFAAHDLFGHVVVHGMWTGALVSAVLGTKLPGPGTIYLDQTLEFRHPVAPGDTITATVTVAEKRPEKRIVLLDTRCTNQDGHVVLRGTATVIAPDTPITWERVPGPEVAVRRHDRYETFVRDAREQPPLRTAIVHPCSPDALRAAIDARDANLIEPILIGPQAKIRAIADAAGVDLAGVPIEAVEHSHAAAARAVEMGGAGEVAALMKGSLHTDELLAAVIGPASRLRTERRISHVYAMDVPAYPKPLLITDAAINIAPTLEQKRDICQNAVDLLHVLGVERPRVAVLAAVETVNPKMPSTLDAAALTVMAARGQIAGAIVDGPLAFDNAVSAVAAMSKGIASPVAGDADVLLVPDLEAGNMLAKQLMYFAGADAAGLVLGTRLPIILTSRADSLRVRIASAALAKLVAERTRAGALAS
>NC_009079.1|WP_004188458.1|116886_118065_-|acetate/propionate-family-kinase
MSEPLLLTFNAGSSTLKIGLYSVANGEPAPLGRGKIDFNRAPLQFEYANGGEAHAVPLAAPVTDDLHAVLDEALGWIDAHLSVHELVSVGHRVVHGGDTFDGPVRIDERTLDAIAALVPLAPLHQPQSVRLIRALRHVRPHLPQVASFDTAFHRTQSDLVRRFALPRALFDAGIKRYGFHGLSYRYVAGRLRERHPSIARGKVVAAHLGSGASLCALDAGVSRDTSMGFSTLDGIPMATRCGALDAGVVLHLQKTLGRTLDDVEQMLYHRSGLLGVSGVSGDARALLADPSAGARDALELFAFRIAGETARLAATLGGLDALVFTAGIGEHQPQTRAAVCERLRWLSVELDAHANARNAETVSRDGSRVAVLVVPTDEEQVIARDAASVLHA
>NC_009079.1|WP_004188355.1|126157_128170_+|F0F1-ATP-synthase-subunit-alpha
MTPTPDAPAAADAATGAGWLARRRGALARVALAPIAQAIGRVERVADGIAFVSGLEDTMLNEVLRFEGGVTGFAHTLDEDLISVVLLDPDAGVRAQTAVARTGAVLEVPAGPQLLGRVVDPLGRPLDGGAPLDAAHTLPIERAAPAIIERDLVSEPLDTGVLIVDALFTIGRGQRELIIGDRATGKTSLAIDAIVNQRHSDVICVYVAIGQRASAVRRVIDAVRRYGAPERCVFVVAPAACAPGLQWIAPFAGFSIAEYFRDRGQHALVVVDDLTKHAATHRELALLTREPPGREAYPGDIFYVHARLLERAAKLSAALGGGSLSALPIAETDAGNLAAYIPTNLISITDGQIVLDSALFAANQRPAVDVGLSVSRVGGKAQHPALRAASGRLRLDYAQFLELEAFTRFGGLTDARLRAQITRGERIRALITQPRFRALRTLDEVVLLKALAAGTLDAMSPDLVAPLRERLPAWLDARIAALTPALAPPRDWLADDAALDALAESVGELIERIAADAARRATAGMPAEDAAGDIGGAFGGEQARGDADRDADHGANREVSREVSPEASREVSREVSREVSHEADRDAAADAARVAGRAPGRAEPDRAVPRAMPDGPPRAQADGDRASASRPPPDARGDAARTAPSPQGGADANVNADANVDAEAEARHKR
>NC_009079.1|WP_004188303.1|128166_129015_+|F0F1-ATP-synthase-subunit-gamma
MSDKLAAIEARTDTARQLQTVIGAMQGVAAARAHEAQQRLPGIRASAATVGAAIGDALSAGARSGETAAGARAAPRARFVVVLCSEQGFVGAYNAQLIEHATRPGPSVSREYMMVGSRGAMLADAGGVPLVWRTPMAARADDVVHLANRITDALYAHLAKRGAQPVSIVHAMPGGAARLEVTERRLLPFDYARFDTAPRAQPPLVHLPPATLLAELAQAYVFVELCEAAMLAFAAENEARTRAMIAARESVERALGDLLQAYRIARQDEITADIVELAASGL
>NC_009079.1|WP_004198321.1|129229_130255_+|alcohol-dehydrogenase-AdhP
MAQYMKAAVVHAFGEPLRIEEVPVPTPGAGQILVNVKASGVCHTDLHAADGDWPVKPTLPFIPGHEGVGFVAAVGEGVRHVKEGDRVGVPWLYTACGHCEYCQTGWETLCHEQQNTGYSVNGSYAEYVLADPNYVGHLPSNVAFDEIAPILCAGVTVYKGIRVTDTRPGQWIAISGIGGLGHVAVQYAKAMGLHVVAVDVAPQKLELARKLGATFVVDASKDDPAAVIQKEIGGVHGVLVTAVSRGAFAQALGMVRRGGTVSLNGLPPGDFPLPIFSTVLNGITVRGSIVGTRRDLQESLDFAAEGLVRAHIHRDKLEHINGVFSALREGKVDGRIVLTGQ
>NC_009079.1|WP_004198322.1|130331_130835_+|hypothetical-protein
MRGAGRASPSRARRYENVSKEPNTHREAGAPVHRYRLQVRNMNGECRTYELRLSSLDDGYTLEIDEWLNFPDTHLGDVTPVHVSRPVQFAVPAHEFYRRRRAFRTELIESVAAALRAGEVVRMRDSPDEYPGGHAGNPWVNWIRADLRANPGGRPPPVGDDMQDLIH
>NC_009079.1|WP_004187158.1|130892_131402_-|hypothetical-protein
MRRIYFLLPDADTARAIVDELLLKRIEWRHIHVVANDRVPLENLPEASIAQSSDLLPALARGTAADGVTGALAGLAAIAFPPAGLTIAGGAVVAFAIAGAGFGAWVSTMIGVSVPNTRLKHFEDAVDNGELLMMIDVHRDRVEEIEALVKQHHPNAHLEGTDPTIPAFP
>NC_009079.1|WP_044302747.1|131903_133508_+|methyl-accepting-chemotaxis-protein
MAPFHRRTTRNARTPTLSFRQKLWLPLVISLIALLLVSISSAWLSYQTRMEERRNDLTNVAHVGLSIVREYAALAQRGVLTDAQARKEALERLRSVRYGSDGYFIVIDSSPRMIMHPIKPDTVGKDLRHVADADGRHHYLTFASVAQSPQGGFVDYVFAHPNAHPAKAVDKLGYVIRYAPWDWIISTGAYIDDIQAAFAKSLCLSAGVFALLAALLALSVVYTNRGIERMIGGDPRIAAHMAGVIASGDLATPFATRREDRSSLMFAISQMRDALANAVAQIRASAGYVATTAGEIADSNMDLSSHTECQATALQQAASSMQRLTERVRDTADRARAASELAGSAARITDRGGDMVVRVVAAMNDIRAESRKMVDIIGVIEGIAFQTNILALNAAVEAARAGNEGRGFAVVASEVRVLAQRSASAAKDIRALIGRAAERVGNGAELVEATGATIGEAQHAICRVTGIVQDIAAAATDQSQGLEQINAAVSQMDSVTRRNATLVEHAAIAAQSLNEQSRCLQDAVAAFRTEALGC
>NC_009079.1|WP_004198323.1|133599_133758_-|hypothetical-protein
MRARRSHGAGIRLGFDKPSGTHSSPHDGWVQTDIAMRLPQISLMPDQALANE
>NC_009079.1|WP_011857754.1|133851_135687_-|response-regulator
MHVEVFAQHPSCPGWHGEMARRIRAFDWSATELGPLERWPASLVAAVRTVLASPVPLVMLWGASGYMLYNDAYAAFAGGRHPYLLGQPVELGWPEVADFNRNVMRTCLAGGALSYRDKALVLLRNGRPEEVWMDLYYSPLAGDDGAPAGVLVVVVETTERVLAARHRDRAKAALHETNAELRRLTETLEQRVADAITERASIEEQLRQAQKMEAIGSLTGGIAHDFNNVLQVVSSNLQMLSAELGEDARAQRRIASAANAVARGAQLASHLLAFARRQPLAPAVLDPRGLIDGMREMLHRALGESVHVDADLRDDVWNVLADRHQFENALLNLAINARDAMRGEGTLKITACNIVLEAGRHARRNGLPPGEYVAFDIADNGVGMTPDILERVFEPFFTTKPDGQGTGLGLSMVFGFVKQSGGHTSIESAPGRGTTVRLLLPRCREAPAGEPAAQRRLPAEGGRETILVVEDDADVRLAVVDMLAQLGYKVITASDGKAGLLALESGAPIDLLFTDVIMPGRIKGGELARRAAQRVPPVPVLFTSGYTRDEIFHAGRLDPGVMLLGKPYRRDELAHKVRSVLDAHASARRAHGARHAQADPRAKTAAARVQR
>NC_009079.1|WP_004188525.1|135836_136961_-|ABC-transporter-permease
MRRLAIIYRLGVKELWSLVRDPILLVLIAYTFTASIYSAATARPDTLHMAPIAIIDEDASPLSARIASAFFPPQFALPRMVTLAEADRGMDAGDFTFALDIPPNFQRDVLAGRPAQIQLNVDATRMSQAFTGNGYVQQIVSGEIDDFARRYRANTAPPVDIAMHMRFNPNLDQTWFGSLMEVINNVTLLSMVLTGAALIREREHGTIEHLLVMPVTPGEIMLAKVWSMGLVVACAAAFSLAFVVRGALHVPIEGSVALFVIGMAIHLFATTSMGIFLATLVRSMPQFGMLLVLVLLPLQLLSGSLTPRESMPFAVQNIMLAAPTTHFVEIGQAILYRGAGIETVWRQFLILAVIGTALFLLSLKRFRKTIGQMA
>NC_009079.1|WP_004203331.1|136963_140203_-|ATP-binding-cassette-domain-containing-protein
MSAPSVVRFSDVSLRYGKTVALERITLEIPAGLTIGLIGPDGVGKSSLLALAAGARALQTGAVDALGGDMRSRRHRERVCRRIAYMPQGLGKNLYPTLSVEENLQFFARLFGHDADERRRRIDALTRSTGLFAFLSRPAGKLSGGMKQKLGLCCALIHDPDLLILDEPTTGVDPLARAQFWDLIARIRSERPAMSVIVATAYMDEAQRFDWLIAMDAGRVLATGAPAELLARTGCDSLEAAFIALLPEDERRGHKPVTLEPLRADAQTGTAIEARGLTMRFGDFTAVDHVSFRIRRGEIFGFLGSNGCGKSTTMKMLTGLLPATEGTAQLFGKTVDPKDINTRRRVGYMSQAFSLYSELTVRQNLVLHARLFGVPAAEIDARVDEMARRFGLADIYDMLPDSLPLGMRQRLSLAVAMVHKPELLILDEPTSGVDPVARDSFWQLMIDLARRDRVTIFISTHFMNEAQRCDRISLMHAGRVLASDAPAALVRARGAATLEEAFIGYLVDASAQEAQEAQGGAGERPGAGERAAGESVAGRGAATDGDADGAHARPAAYANGAAQHRAPDADAAGTDVAAETGARDDARTAHAAGHSAGNDVRATVGSEVGSEVGSDVGSEVASEAGLAASAESGSERGVAHGAERAREPAADAGAAIDVEPGASAESATAAVAPARHAESAATSPRAGNAPAGTPFAAAPAEPPHRAFSAQRALSYMWREMLELRRDPVRATLALIGSLVLMCVIGIGISLDVEDLTYAVLDRDQTELSHDYALNLSGSRYFVERPPIADYAALDRRMRDGELSLAIEIPPNFARDVERGAPAQIGMWIDGAMPQRAETIRGYAIGMHTMWLADKARHRLGVTLAPRAEVVTRYRYNPDVKSLPAMIPAVMPLLLLMLPAMLTALAVVRERELGSILNLYVTPVTRTEFLIGKQVPYVVLAMLNFLLMTMLARIAFDVPVKGSFMTLLLAVLIFNVVATGIGLLASTFTRSQVAAIVMTIIGTMIPTVQFAGLLTPLSSLEGTGRLIGLVYPATYMLSISRGVFNKALSLHELYSQFWPLAACVPVILGATILLLKKQER

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Crispr_ID: NC_009079_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_009079_2

1160697-1160859

Orphan

Consensus_repeat	Method
GGCGGGCCGGCCGCCG---------------------------CGCGGGCG	PILER-CR

2 spacers

The CRISPR arrays of NC_009079_2

>merge|NC_009079|2|1160697-1160859|PILER-CR
GGCCGCTCGGCCGCCGCGCGGGCGCGTGTTCCACGTGGCGGCCTGCGCCGTGTCGGCCGCGGCGGCCGTGCGGAGCGGGCCGGCCGCCGCGGCGATGGTGGCCGCGCGGATCACGTGGATCACGTTGACGGCGTTGAACGGCGGGCCGGCCGCCGCGCGGGCG

>NC_009079|2|1|1160697-1160859|PILER-CR
GGCCGCTCGGCCGCCGCGCGGGCG	CGTGTTCCACGTGGCGGCCTGCGCCGTGTCGGCCGCGGCGGCCGTGCGG
AGCGGGCCGGCCGCCGCGGCGATG	GTGGCCGCGCGGATCACGTGGATCACGTTGACGGCGTTGAACGGCGGG
CCGGCCGCCGCGCGGGCG

Protein	Signature genes	Signature genes Name	Protein_function
NC_009079.1\|WP_004199160.1\|1168916_1172018_+\|MMPL-family-transporter	unknown	unknown	gnl\|CDD\|169983
NC_009079.1\|WP_004184876.1\|1167822_1168920_+\|efflux-RND-transporter-periplasmic-adaptor-subunit	unknown	unknown	gnl\|CDD\|273776
NC_009079.1\|WP_073699266.1\|1173687_1174002_+\|hypothetical-protein	unknown	unknown	unknown
NC_009079.1\|WP_004199157.1\|1167000_1167672_-\|transcriptional-regulator	unknown	unknown	gnl\|CDD\|225222
NC_009079.1\|WP_004197875.1\|1156260_1156545_-\|hypothetical-protein	unknown	unknown	unknown
NC_009079.1\|WP_004197874.1\|1156058_1156244_-\|hypothetical-protein	unknown	unknown	unknown
NC_009079.1\|WP_004197879.1\|1157752_1158241_-\|membrane-protein	unknown	unknown	gnl\|CDD\|377190
NC_009079.1\|WP_004199606.1\|1161722_1163723_-\|ATP-dependent-zinc-metalloprotease-FtsH	unknown	unknown	gnl\|CDD\|273520
NC_009079.1\|WP_133307164.1\|1154639_1155998_-\|TolC-family-protein	unknown	unknown	gnl\|CDD\|224455
NC_009079.1\|WP_004266238.1\|1172152_1173691_+\|efflux-transporter-outer-membrane-subunit	unknown	unknown	gnl\|CDD\|182103
NC_009079.1\|WP_004524134.1\|1156942_1157083_-\|bacteriophage-protein	unknown	unknown	unknown
NC_009079.1\|WP_004197880.1\|1158567_1159053_+\|YbaK/EbsC-family-protein	unknown	unknown	gnl\|CDD\|239824
NC_009079.1\|WP_004202583.1\|1149880_1153114_-\|CusA/CzcA-family-heavy-metal-efflux-RND-transporter	unknown	unknown	gnl\|CDD\|129992
NC_009079.1\|WP_004197883.1\|1160975_1161584_+\|rhomboid-family-intramembrane-serine-protease	unknown	unknown	gnl\|CDD\|223777
NC_009079.1\|WP_004184790.1\|1159320_1160676_+\|amino-acid-permease	unknown	unknown	gnl\|CDD\|163522
NC_009079.1\|WP_004197872.1\|1153159_1154629_-\|efflux-RND-transporter-periplasmic-adaptor-subunit	unknown	unknown	gnl\|CDD\|273386
NC_009079.1\|WP_004205924.1\|1157534_1157765_+\|hypothetical-protein	unknown	unknown	unknown
NC_009079.1\|WP_004537230.1\|1163776_1164289_-\|hypothetical-protein	unknown	unknown	unknown
NC_009079.1\|WP_011204479.1\|1164346_1164979_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|237057
NC_009079.1\|WP_011857799.1\|1165103_1166870_+\|amidohydrolase-family-protein	unknown	unknown	gnl\|CDD\|226179

Protein	Function_ID	Function_description	E-value
NC_009079.1\|WP_004199160.1\|1168916_1172018_+\|MMPL-family-transporter	gnl\|CDD\|169983	PRK09579, PRK09579, multidrug efflux RND transporter permease subunit.	0
NC_009079.1\|WP_004184876.1\|1167822_1168920_+\|efflux-RND-transporter-periplasmic-adaptor-subunit	gnl\|CDD\|273776	TIGR01730, COG0845:_Membrane-fusion_protein, RND family efflux transporter, MFP subunit. This model represents the MFP (membrane fusion protein) component of the RND family of transporters. RND refers to Resistance, Nodulation, and cell Division. It is, in part, a subfamily of pfam00529 (Pfam release 7.5) but hits substantial numbers of proteins missed by that model. The related HlyD secretion protein, for which pfam00529 is named, is outside the scope of this model. Attributed functions imply outward transport. These functions include nodulation, acriflavin resistance, heavy metal efflux, and multidrug resistance proteins. Most members of this family are found in Gram-negative bacteria. The proposed function of MFP proteins is to bring the inner and outer membranes together and enable transport to the outside of the outer membrane. Note, however, that a few members of this family are found in Gram-positive bacteria, where there is no outer membrane. [Transport and binding proteins, Unknown substrate].	9.65507e-71
NC_009079.1\|WP_004199157.1\|1167000_1167672_-\|transcriptional-regulator	gnl\|CDD\|225222	COG2345, COG2345, Predicted transcriptional regulator [Transcription].	5.95232e-60
NC_009079.1\|WP_004184790.1\|1159320_1160676_+\|amino-acid-permease	gnl\|CDD\|163522	TIGR03810, arginine-ornithine_antiporter, arginine-ornithine antiporter. Members of this protein family are the arginine/ornithine antiporter, ArcD. This exchanger of ornithine for arginine occurs in a system with arginine deiminase, ornithine carbamoyltransferase, and carbamate kinase, with together turn arginine to ornithine with the generation of ATP and release of CO2. [Transport and binding proteins, Amino acids, peptides and amines].	4.43391e-175
NC_009079.1\|WP_004197879.1\|1157752_1158241_-\|membrane-protein	gnl\|CDD\|377190	pfam04008, Adenosine_kin, Adenosine specific kinase. The structure of a member of this family from the hyperthermophilic archaeon Pyrobaculum aerophilum contains a modified histidine residue which is interpreted as stable phosphorylation. In vitro binding studies confirmed that adenosine and AMP but not ADP or ATP bind to the protein.	3.29857e-108
NC_009079.1\|WP_011857799.1\|1165103_1166870_+\|amidohydrolase-family-protein	gnl\|CDD\|226179	COG3653, COG3653, N-acyl-D-aspartate/D-glutamate deacylase [Secondary metabolites biosynthesis, transport, and catabolism].	1.70819e-150
NC_009079.1\|WP_133307164.1\|1154639_1155998_-\|TolC-family-protein	gnl\|CDD\|224455	COG1538, TolC, Outer membrane protein [Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion].	3.39198e-32
NC_009079.1\|WP_004199606.1\|1161722_1163723_-\|ATP-dependent-zinc-metalloprotease-FtsH	gnl\|CDD\|273520	TIGR01241, ATP-dependent_zinc_metalloprotease_FtsH, ATP-dependent metalloprotease FtsH. HflB(FtsH) is a pleiotropic protein required for correct cell division in bacteria. It has ATP-dependent zinc metalloprotease activity. It was formerly designated cell division protein FtsH. [Cellular processes, Cell division, Protein fate, Degradation of proteins, peptides, and glycopeptides].	0
NC_009079.1\|WP_004197880.1\|1158567_1159053_+\|YbaK/EbsC-family-protein	gnl\|CDD\|239824	cd04332, YbaK_like, YbaK-like. The YbaK family of deacylase domains includes the INS amino acid-editing domain of the bacterial class II prolyl tRNA synthetase (ProRS), and it's trans-acting homologs, YbaK, ProX, and PrdX. The primary function of INS is to hydrolyze mischarged cysteinyl-tRNA(Pro)'s, thus helping ensure the fidelity of translation. Organisms whose ProRS lacks the INS domain express an INS homolog in trans (e.g. YbaK, ProX, or PrdX).	4.00352e-32
NC_009079.1\|WP_004202583.1\|1149880_1153114_-\|CusA/CzcA-family-heavy-metal-efflux-RND-transporter	gnl\|CDD\|129992	TIGR00914, Nickel-cobalt-cadmium_resistance_protein_NccA, heavy metal efflux pump, CzcA family. This model represents a family of H+/heavy metal cation antiporters. This family is one of several subfamilies within the scope of pfam00873. [Cellular processes, Detoxification, Transport and binding proteins, Cations and iron carrying compounds].	0
NC_009079.1\|WP_004197883.1\|1160975_1161584_+\|rhomboid-family-intramembrane-serine-protease	gnl\|CDD\|223777	COG0705, COG0705, Membrane associated serine protease [Amino acid transport and metabolism].	8.96274e-30
NC_009079.1\|WP_004197872.1\|1153159_1154629_-\|efflux-RND-transporter-periplasmic-adaptor-subunit	gnl\|CDD\|273386	TIGR00999, Nickel-cobalt-cadmium_resistance_protein_NccB, Membrane Fusion Protein cluster 2 (function with RND porters). [Transport and binding proteins, Other].	4.97736e-65
NC_009079.1\|WP_004266238.1\|1172152_1173691_+\|efflux-transporter-outer-membrane-subunit	gnl\|CDD\|182103	PRK09837, PRK09837, Cu(I)/Ag(I) efflux RND transporter outer membrane protein.	5.59568e-111
NC_009079.1\|WP_011204479.1\|1164346_1164979_+\|hypothetical-protein	gnl\|CDD\|237057	PRK12323, PRK12323, DNA polymerase III subunit gamma/tau.	0.00628281

>NC_009079.1|WP_004184790.1|1159320_1160676_+|amino-acid-permease
MKHSVRHPFHPSTPLPASASAPLRAAAPRQLPFALLTALVIGSMIGSGIFSLPQNMASGAGAGAIVIGWAITGVGMLMLALVYQTLAHRKPELDNGVYAYAHASAGDFVGFNSAWGYWVSAWIGNVGYLVIVFGTLGYAFPAFGDGNTRAALAFQPHRFTTDFWGNVHLPGVLDQVKSTMLITVWVFIGIEGASVYSARAKNRDDVGRATIVGFVVVLLLLMAVSLLSLGIVSQPELAAMKNPSMAGVLEKAIGRTGVAIAGVGLLVSVGGALLAWTLLAAEAMFTPAKDGVMPAFLSRENAHGVPANALWATNGLVQLFLLVTLVSNATYQALISLATSMILVPYLFSAVYALVIAIKGEGYAPGEAVRVRDATIGAVATVYCGWLLYAAGPKYLLLSALLYAPGALLYAWAKRERGERPFKPFEAAILIALVAFASLAGWLVAAGRISL
>NC_009079.1|WP_004197880.1|1158567_1159053_+|YbaK/EbsC-family-protein
MSMSVTLQECLRQKASRYEVIHHPYSHSNMEAAAAAHVPGDRLAKTVLLEDAQGYVAAVLPTTHAVRLSELWAKTGRHLVLAKEVELRELFKDCDVGALPPVCMAYGMQTFLDDSLARQPDVYFEAGDHEELVHMDRDEFLALMDKAERASFSHKIQGVVS
>NC_009079.1|WP_004197879.1|1157752_1158241_-|membrane-protein
MLQLLSVAIDKPDTANFILGQTHFIKSVEDIHEALVGAVPGIRFGLAFCEASGKRLVRHSGTGAALTELACRNALAIGAGHCFLVFLGDGFYPLNVLNAIKAVPEVCRIFCATANPTEVVVAQSDQGRSILGVVDGFSPLGIETDEDVRWRKDLLRNIGYKA
>NC_009079.1|WP_004205924.1|1157534_1157765_+|hypothetical-protein
MQAVRSPLSRYRGWHGRASAMRTGPGLHGEAATDDRQSITGNPQSTHRTQARKRARFGQSPRDPAQDAATRGGYAL
>NC_009079.1|WP_004524134.1|1156942_1157083_-|bacteriophage-protein
MSLAAQDLIELLRLAQGGAGALTLHLLREIAGNLIAFGVADCRGGC
>NC_009079.1|WP_004197875.1|1156260_1156545_-|hypothetical-protein
MKRATSLAFAALFALAASSAFAHGMPERVFKERKPIRADARQEPSQRDASSAGCASGCPAGAALSRQDDRASGASPSSVGVEAAAGVHPAVNGG
>NC_009079.1|WP_004197874.1|1156058_1156244_-|hypothetical-protein
MRRGGALMRGRRTLDAPRPPAPPAPFLAPPHARASPRRIQPAAANVTKMSCSPHVCIAARP
>NC_009079.1|WP_133307164.1|1154639_1155998_-|TolC-family-protein
MSAAIAASAVQAQAQPAPAPSAPDGPAAAPPDARAASVSVTPAVSPAPISTSTVSVAPPALSLDDALALAAANNPLLKSARSSADASVGALVQAGARPNPTVSFLQEGFGRQERTTTAVVSQPIELGGKRRSRVDAASYGRESALASLDGRAAALRADVTGAFYGVLAAQRQLQVADESAAIAARSADMADKRARAGKVSPVEATKARVAQTAAQIELSNAQTRVAAALARLANATGSADVRGRAASGDLDALPAAEPLPQLLGRLDDAPLARAAKADMLRTNAQIAIERAKRVPDITVSAGVKHVVTGGAPDNQAVVGISIPLPLFDTNRGALLEAVHNAAKASADFDAERARLRLDLTQAYANYERATGEARRLKADVLPAARQSLDAMSRGYQLGKFGFLDVLDAQRTLFDAQSRYVQALADAHQSYADIERVVGAPARDASRPLAQLR
>NC_009079.1|WP_004197872.1|1153159_1154629_-|efflux-RND-transporter-periplasmic-adaptor-subunit
MQRKPLILAGAAAAGALAIVLALARAPSTSSAPAASGAAAAAPASGATGPHGGAMFAQGALSAEIVLSEKPDDARLVVYPFVDGKPVEQGAAVSATLTRHDGERVALQFAQAGAKYTSAQPIARPHVFDASIDVRIGARSASFPFSRADGAIALDDAQLGAARIGIARAGPAQIITSFQLPGEIKFNEDRTAHVVPRVAGIVERVAVSIGENVKPGQVLAVIASTDLADRRSELMTAERRLQAARTSYAREKTLWEERISAEQDYLQAQVQLREAEIAAANARQKLAALNASAASGALNRYELRAPFAGTIVEKHIAPGEAIAADANVFVVSDLSSVWAEMAVPAQRLNDVRVGRHATVSAAAFESKSSGPIAYVGALLGEQTRTAPARVVLPNPDGAWRPGMFVNVTVDAGAQNVPVAVESDALQDVDGAPAVFVRTPKGFVAQAIETGRRDERRVEIVKGLAPGQTYAAANSFVLKAELGKGVADEH
>NC_009079.1|WP_004202583.1|1149880_1153114_-|CusA/CzcA-family-heavy-metal-efflux-RND-transporter
MFERLIRFAIAHRWLVMLAIVAAASLGVYSYQKLPIDAVPDITNVQVQVNTSAPGYSPLEAEQRITYPVETAMAGLPNLEQTRSISRYGLSQVTVIFKDGTDIYFARQLVNERIQEAKDKLPPGIAPAMGPTSTGLGEIYLWTVEADAGARKPDGTRYTSADLRELQDWVVRPQLRNVPGVTEVNSIGGYVKEYRVAPNPTKLMSYGLTLADVVRALERNNDNVGAGYIEKRGEQYLVRVPGQARSAEDIANIVLVNAGGVPVRMKDIGAVDLGRELRTGAATANGEEVVLGTVFMLMGENSRTVAKAVAARMADVNRTLPAGVRAIAVYDRTVLVEKAVRTVKKNLLEGAVLVIAVLFLFLGNIRAAVITALVIPLSMLMTFTGMVNAKVSANLMSLGALDFGIIVDGAVVIVENCIRRLAHAQQAAGRPLTRDERFAEVFAASQEARRALIFGQLIIMVVYLPIFALTGVEGKMFHPMAITVVMALAAAMALTVTFIPAAVALFIGRRVEEKENRLMSAAKRLYAPVLDAFVARPGQVLAGATAVVALSLVLATRLGSEFIPSLNEGDLAVSAQRIPGTSLTQSVAMQQSIEKTLKARFPEIDRVFARTGTAEIAADPMPPNLSDGYIMLKPADQWPDPRKSRDALRGEIEAVLAQLPGNAYEFSQPIQLRFNELISGVRSDVAVKIFGDDMATLNATGEQIAAALQKVPGASEVKVEQTTGLPVLTVNLDRDKLARYGVTVGDVQDTVAAAVGGRKAGLLFQGDRRFDIVVRLPDELRTDVEAIKRLPIALPLAAPAGASGPLAQAPYVPLAELATVDTSPGPNQISREDGKRRVVVSANVRGRDVGSFVADARERIASDVRVPAGYWLSWGGQFEQLQSASERLKIVVPLALAMVFVLLFVMFNNAKDGLLVFTGIPFALTGDVVSLWLRGIPLSITAAVGFIALSGVAVLNGLVMISFIRNLRDEGAPLDAAVREGALTRLRPVLMTALVASLGFLPMAFATGTGAEVQRPLATVVIGGILSSTALTLLVLPVLYRVAHAAPPRATLGARAAGWLARLAPAAVLRRRRESSR
>NC_009079.1|WP_004197883.1|1160975_1161584_+|rhomboid-family-intramembrane-serine-protease
MTLAIVVLNVIGFLVELAAPERVLSLFALWPPRAGAGLPPAAAPAFHVWQLVTYSALHAGLSHLLFNMLGLVMFGRDVERALGRARFGTLYLASVVCGALTQLALARYSAAAAAPTIGASAGVFGVLAAYALLYPSRRVVLLIPPIPMRAWVFALLYAGGELLLGVAGAASGIAHFAHLGGMFGAIALMLAWGRPRSEWPVQ
>NC_009079.1|WP_004199606.1|1161722_1163723_-|ATP-dependent-zinc-metalloprotease-FtsH
MKSETGYMGFVVVLVFMVLLALQLATLSAPATQIAYSDFRKLAAAAQLDDLEVSPTRITGVLRSASAAAALPASDAEAIKRAGTPWRFSTKRVTDERLIDTLAATGTRYRGADDDTWIGTLASWIVPIAVFALVWNLMLRRPRGGLQDWSGVGKSKPRVYVEAKTGIDFDDIAGIDEAKAELQQIVAFLRAPARYQRLGGKIPKGVLIVGAPGTGKTLLAKAVAGEAGVPFFSTSGSSFVEMFVGVGAARVRDLFEQAQQKAPCIIFIDELDALGKVRGAGLASGNDEREQTLNQLLVEMDGFQANSGVILMAATNRPEILDPALLRPGRFDRHIAIDRPDLTGRRQILSVHVKHVKLGPDVDLGELASHTPGFVGADLANIVNEAALHAAELDKPAIDMSDFDEAIDRAMTGMERKSRVMSEREKITIAHHEAGHALIAQTRAHSDPVKKVSIIPRGIAALGYTQQVPTEDRYVLRKSELLDRLDVLLGGRVAEEIVFGDVSTGAENDLERATEMARHMVARYGMSERIGLATFGDADTQGLSPLVWQRGGERCSESTATRIDDEIQRLLAEAHDRVSRTLKERRGALERIAGYLLEHEVVDHDKLVRLVNDEPTPEPGARDPGGDAAKRSGIGAAPAKPPAEVGSAELRDPARKADNADHSVPQ
>NC_009079.1|WP_004537230.1|1163776_1164289_-|hypothetical-protein
MIYGSNELYAAMRQRRDRLPRAHPADGYGAPARLKSGMGCTECGALYDDGRWSWHAAAGALLQIVCPACRRIRERASAGELVLEGGYFARRRDDIVALLRRHAGDDINARPLGRILSIDALPARMVVRTKGSPLVHRLTEALVRTHRGDLEIDYREGEDTLRAHWMRDAA
>NC_009079.1|WP_011204479.1|1164346_1164979_+|hypothetical-protein
MRGRRRNRGIAGMRSMAVRGATYTTEHRRSPARAIDADQRSATSRRFARADWCGFVANRSEPARSPMPAADSRVRAGRGRARVVAASGRIPAVTRSRACRHGVRPMKVSGARRASAAAAYPVAPRAQPRPRSRPAGDAAVQHAVAVARVAAARRRRGRGSAEPMPHEGAARSGARSCVAPRDRRACCVRRARASDESMRRFEAMLACNSS
>NC_009079.1|WP_011857799.1|1165103_1166870_+|amidohydrolase-family-protein
MTRYDTIIRNGLWFDGTLAEPRPRELGIRDGRVAAVSDTPLAADGASVIDATGKWVMPGFIDIHTHYDAEILVSPGLPESVRHGVTSVFLGSCSLSTVHANALDCTDLFSRVEALPREQMLAVLSRVKTWDTAAAYVRHLESLPLGPNVAAFLGHSDLRTHVLGLGRAVDDRVRPHEAELQRMERLLDDALDAGFVGLSSMTTPWDKLDGERYRSKSLPSTFATWREYRRLNRVLRRRGRVLQSAPNTTNPLNGLLFMAESCGYFVRKPLRTSLLVAADSKAAPRGTIDVQLGGVRVANALFRGELVWQHLPVPFEVYADGIDFVIFEEFGAGRAALHLADALERNKLLQNEGYRREFRRQVGKGFDLRLWTRDLHDTRIVGCPDASVVGKSFGQVANERGVHPADAFLDLVVAHGQRLRWCMTIANHRADVLDRIAPHPALQIGFADSGAHLRNMAFYNAPVRFLRRVREAERAGRPFMSVQQAVHRLTGELGAYFGVDAGTLRAGDRADIAIVDPAHLDASVDASVDAYHEEDMAVFGGLRRLVNRSGAAIAATLVNGQLVYRDGAFAEGFGDTRRSGRFLRAAAR
>NC_009079.1|WP_004199157.1|1167000_1167672_-|transcriptional-regulator
MDDNFSKQEIPVSERVLNVLKRRGPLQAAELGAYLGTTGEAARQQLKKLEAEGLVEAQNVPQGVGRPARIWRLTSLGHGHFPDAHADMTVDLIRIIRTTLGQPTLDLLIAARETEMRRTYAHTLAGVTDPEERIARLAELRDREGYFAEWSRAPDGDGWLFIENHCPICAAATACQGFCRSELEIFREMLGDALTIERIEHIPAGARRCAYRIRPSGAGAGGE
>NC_009079.1|WP_004184876.1|1167822_1168920_+|efflux-RND-transporter-periplasmic-adaptor-subunit
MGRRLLLALALLAFIFGGLFLWRESRVQAADHPPAPPAALTVSAVAVRAAPERVTLDAVGSLDAVRQVTLAPEVAGRVVALQFDAGSAVRKGQLIVQLFDEPERAKLASIQAKAAYAKRQLDRSQALAQTGAEPRNLFDRHRFDFDAAAADIRETQAVITQKAVRAPFDGVLGLRRVNLGQYLNAGDAIATLTDLDTLYANFTVPQKNLSQLRLGQSVSITTDAYPERTLVARVSAIEPQIGTDTRNVAVQATLPNPDHLLRPGMYIQARLELPPRERALTVPDTAVQTSQRGESVLVVGKPGRDGLGVVRLQPVRTGRRADGRIAIADGLRPGDVVVTSGQVRLAAGDRVKVALDDGAGSGAAQ
>NC_009079.1|WP_004199160.1|1168916_1172018_+|MMPL-family-transporter
MNAGAPHDSGAARARFTDVFVRRPVLSLVFSLLILLVGLRALMSLPVRQYPALESATISVATDYPGASQELMQGFVTTPIAQSIATADGIEYITSTTTQGKSVVKARLRLNANADRAMTEVMAKVQQVKYKLPADAYDSVITKLTDAPTAVMYLGFASDALSIAQITDYVVRVAQPLVTTVPGVASAEILGGQNLAMRVWLDATRLAAHGLSAGDVAAAIRANNVQAAPGQVKGSLTIADISANTDLTDVGAFNEMVVKSAPNGGGLVRLKDVATVEIGGENYNSSALMNGRRAVYIAVNATPAGNPLEIVRGVGAVLPAIERNKPASVQIANMFDGARFVNASIAEVRSTLTEAIAIVVVVIFLFLGSFRAVIIPVLTIPLSLVGSAALMLAAGFSLNLLTLLAMVLAIGLVVDDAIVVVENIHRHIEQGEPPVRAALIGAREIASPVLVMMATLISVYAPIGLMGGLTGLLFKEFAFTLAGAVLVSGIVALTLSPMLGSLLLTSRMSEGRVAKAIERTLERVTHAYRRGLHASLAARPAILLIGAGVLAGIVLLFSGVKRELAPQEDQGSIMVAVKAPQYANLDYMERYAPDIERVFRTLPEADTSFILNSYGGSNLGFAGVNLVDWDKRTRSAAALQALIQARGDGIRGERVFAFQLPALPASSGGLPIQMVLRTPSGFADLYAQMERIKAAAQKSGLFAVLDSDLTFDSRAVGVTIDRNQANTLGVTMKDIADTLAVLVGENYVNRFNFKGRSYDVIPQVSRSERLSSEMLSRYYVKTGSGRMIPLSTVIQVTNGSQANALSQFNQMNAATFSAVPAPGVTMGDAVAFLEAQKLPAGFSIDWLGESRQYVQEGNRLAVTFGFALIVIFLVLAAQFESLRDPLVILVSVPLSICGALAPLYLGFATLNIYTQIGLVTLIGLISKHGILMVSFANDLQRHEGLDRRAAIERAAAVRLRPILMTTAAMVAGLVPLVFAAGAGAASRFAIGITVSTGMLVGTLFVLPTVYTFVAKDHGAAMRSERAQLLAATR
>NC_009079.1|WP_004266238.1|1172152_1173691_+|efflux-transporter-outer-membrane-subunit
MRTAVRAAAVAAAFFAAGCTLAPRYERPAAPVSGAFPADGVYAAQPGAAPGARSANGQAAVDIGWREFFVDPRLQRLIEIALKNNRDLRVSVLNVEASRAQYQITRAGLFPTLSGTGTGTIQRTPAGVSITGQPLISRTYNVGVSASWELDLFGRVQSLKDQALAQYFATAQARKAAEISLVASVADQYLTLLSTDDLLQVTQNTLKSARASYDLTKLQFDNGTGSELDLRQAQTVVETALASQQAQARARAQALNALVLLIGEPLPDDLPADLPLNAQNLLTDIPAGLPSDLLTRRPDIMQAEETLRAANANIGAARAAFFPKISLTSAFGTASTTLGGLFKAGTAAWSFAPNIALPIFEGGQNIANLDLAHVQKRIEIANYEKAIQSAFREVSDGLAARGTYDQQIAALERNEHAQQRRYDLSDLRYRNGVDSYLSVLTAQTDLYSAQQQLISARLARWTNLVDLYRALGGGWLERAGETPRPADAPVDYGKAAPAPAASASARTAAVIG
>NC_009079.1|WP_073699266.1|1173687_1174002_+|hypothetical-protein
MSAQPDMRQPNARQHSARRPSAARAGRERIGRTWRTKKKTDREMIGDTVIGTDAQSAMLLHNRTQQPIKSSPRTRETATNRKSIQAFDITIQKLPCSSRCVSQC

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Crispr_ID: NC_009079_3

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_009079_3

2243497-2243642

Orphan

Consensus_repeat	Method
GCAGAGGCGCCGCCGCCGGAATACCCGATCATCGGGATGCTCGATCGCCGAAG	PILER-CR
CGGAATGCCCGATCATCGGGATGC	CRISPRCasFinder

2 spacers

The CRISPR arrays of NC_009079_3

>merge|NC_009079|3|2243497-2243642|PILER-CR,CRISPRCasFinder
TCGTCGGGATGCTCGATTGCCGCAGTCACCCTCCGCCGGGGCTCCGTCGTCGGAATGCCCGATCATCGGGATGCCTGCTCGCCGAAGCACTCCACCGCAGAGGCGCCGCCGCCGGAATACCCGATCATCGGGATGCTCGATCGCCG

>NC_009079|3|2|2243497-2243642|PILER-CR
TCGTCGGGATGCTCGATTGCCGCAGTCACCCTCCGCCGGGGCTCCGTCGTCGGAA	TGCCCGAT
CATCGGGATGCCTGCTCGCCGAAGCACTCCACCGCAGAGGCGCCGCCGCCGGAAT	ACCCGATCA
TCGGGATGCTCGATCGCCG

>NC_009079|3|2|2243547-2243632|CRISPRCasFinder
CGGAATGCCCGATCATCGGGATGC	CTGCTCGCCGAAGCACTCCACCGCAGAGGCGCCGCCGC
CGGAATACCCGATCATCGGGATGC

Protein	Signature genes	Signature genes Name	Protein_function
NC_009079.1\|WP_004200700.1\|2234786_2235902_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|378454
NC_009079.1\|WP_004187469.1\|2242422_2242818_-\|conjugal-transfer-protein-TraR	unknown	unknown	gnl\|CDD\|224648
NC_009079.1\|WP_004200705.1\|2254094_2254748_+\|SagB/ThcOx-family-dehydrogenase	unknown	unknown	gnl\|CDD\|380318
NC_009079.1\|WP_004196898.1\|2234011_2234452_+\|SRPBCC-family-protein	unknown	unknown	gnl\|CDD\|176863
NC_009079.1\|WP_004187137.1\|2253191_2253641_-\|CBS-domain-containing-protein	unknown	unknown	gnl\|CDD\|341411
NC_009079.1\|WP_004187710.1\|2247626_2249429_+\|bifunctional-aminoglycoside-phosphotransferase/ATP-binding-protein	unknown	unknown	gnl\|CDD\|225098
NC_009079.1\|WP_009950893.1\|2233620_2233926_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|240624
NC_009079.1\|WP_011204702.1\|2255655_2256783_-\|porin	unknown	unknown	gnl\|CDD\|238208
NC_009079.1\|WP_004205322.1\|2236199_2237135_+\|LysR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|176109
NC_009079.1\|WP_004187305.1\|2249951_2250983_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|236122
NC_009079.1\|WP_009927403.1\|2235962_2236073_-\|hypothetical-protein	unknown	unknown	unknown
NC_009079.1\|WP_011832092.1\|2244199_2245426_+\|polyhydroxyalkanoate-depolymerase	unknown	unknown	gnl\|CDD\|130908
NC_009079.1\|WP_011204695.1\|2232962_2233289_+\|hypothetical-protein	unknown	unknown	unknown
NC_009079.1\|WP_004187792.1\|2250979_2252812_+\|STAS-domain-containing-protein	unknown	unknown	gnl\|CDD\|223732
NC_009079.1\|WP_004187216.1\|2240016_2242290_-\|pyridine-nucleotide-disulfide-oxidoreductase	unknown	unknown	gnl\|CDD\|369639
NC_009079.1\|WP_011204697.1\|2238047_2239706_+\|GMC-family-oxidoreductase	unknown	unknown	gnl\|CDD\|225186
NC_009079.1\|WP_011204696.1\|2237316_2237748_+\|hypothetical-protein	unknown	unknown	unknown
NC_009079.1\|WP_004553972.1\|2245767_2247552_+\|ribonucleotide-reductase	unknown	unknown	gnl\|CDD\|180772
NC_009079.1\|WP_011204701.1\|2254815_2255250_-\|Hsp20/alpha-crystallin-family-protein	unknown	unknown	gnl\|CDD\|223149
NC_009079.1\|WP_011204700.1\|2252844_2253219_+\|hypothetical-protein	unknown	unknown	unknown

Protein	Function_ID	Function_description	E-value
NC_009079.1\|WP_004200700.1\|2234786_2235902_-\|hypothetical-protein	gnl\|CDD\|378454	pfam10604, Polyketide_cyc2, Polyketide cyclase / dehydrase and lipid transport. This family contains polyketide cylcases/dehydrases which are enzymes involved in polyketide synthesis. It also includes other proteins of the START superfamily.	2.16274e-11
NC_009079.1\|WP_004187469.1\|2242422_2242818_-\|conjugal-transfer-protein-TraR	gnl\|CDD\|224648	COG1734, DksA, DnaK suppressor protein [Signal transduction mechanisms].	1.7869e-14
NC_009079.1\|WP_004200705.1\|2254094_2254748_+\|SagB/ThcOx-family-dehydrogenase	gnl\|CDD\|380318	cd02142, McbC_SagB-like_oxidoreductase, oxidase similar to the microcin B17 processing protein McbC. This family is the oxidase domain of NRPS (non-ribosomal peptide synthetase) and other systems that modify polypeptides by cyclizing a thioester to form a ring. These include EpoB, part of the epothilone biosynthesis pathway; TubD, part of the tubulysin biosynthesis pathway, MtsD, part of the myxothiozol biosynthesis pathway; IndC, part of the indigoidine biosynthesis pathway and TfxB, part of the trifitoxin processing pathway. All are FMN-dependent and oxidize the product of the cyclization of thioesters in short polypeptides.	6.31252e-20
NC_009079.1\|WP_004196898.1\|2234011_2234452_+\|SRPBCC-family-protein	gnl\|CDD\|176863	cd07821, PYR_PYL_RCAR_like, Pyrabactin resistance 1 (PYR1), PYR1-like (PYL), regulatory component of abscisic acid receptors (RCARs), and related proteins. The PYR/PYL/RCAR-like family belongs to the SRPBCC (START/RHO_alpha_C/PITP/Bet_v1/CoxG/CalC) domain superfamily of proteins that bind hydrophobic ligands. SRPBCC domains have a deep hydrophobic ligand-binding pocket. PYR/PYL/RCAR plant proteins are receptors involved in signal transduction. They bind abscisic acid (ABA) and mediate its signaling. ABA is a vital plant hormone, which regulates plant growth, development, and response to environmental stresses. Upon binding ABA, these plant proteins interact with a type 2C protein phosphatase (PP2C), such as ABI1 and ABI2, and inhibit their activity. When ABA is bound, a loop (designated the gate/CL2 loop) closes over the ligand binding pocket, resulting in the weakening of the inactive PYL dimer and facilitating type 2C protein phosphatase binding. In the ABA:PYL1:ABI1 complex, the gate blocks substrate access to the phosphatase active site. A conserved Trp from PP2C inserts into PYL to lock the receptor in a closed formation. This group also contains Methylobacterium extorquens AM1 MxaD. The mxaD gene is located within the mxaFJGIR(S)ACKLDEHB cluster which encodes proteins involved in methanol oxidation. MxaD may participate in the periplasmic electron transport chain for oxidation of methanol. Mutants lacking MxaD exhibit a reduced growth on methanol, and a lower rate of respiration with methanol.	3.1145e-25
NC_009079.1\|WP_009950893.1\|2233620_2233926_-\|hypothetical-protein	gnl\|CDD\|240624	cd05299, CtBP_dh, C-terminal binding protein (CtBP), D-isomer-specific 2-hydroxyacid dehydrogenases related repressor. The transcriptional corepressor CtBP is a dehydrogenase with sequence and structural similarity to the d2-hydroxyacid dehydrogenase family. CtBP was initially identified as a protein that bound the PXDLS sequence at the adenovirus E1A C terminus, causing the loss of CR-1-mediated transactivation. CtBP binds NAD(H) within a deep cleft, undergoes a conformational change upon NAD binding, and has NAD-dependent dehydrogenase activity.	0.0059154
NC_009079.1\|WP_011204702.1\|2255655_2256783_-\|porin	gnl\|CDD\|238208	cd00342, gram_neg_porins, Porins form aqueous channels for the diffusion of small hydrophillic molecules across the outer membrane. Individual 16-strand anti-parallel beta-barrels form a central pore, and trimerizes thru mainly hydrophobic interactions at the interface. Trimers are stabilized by hytrophillic clamping of Loop L2. Loop 3 bends into the pore, creating an elliptical constriction of about 7 x 11A, large enough to allow passage of a glucose molecule without steric hindrance. Removal of the C-terminal residue (usuallly F) destabilizes the trimer and removal of the 16th beta-sheet abolishes trimerization. Unlike typical membrane proteins, porins lack long hydrophobic stretches. Short turns are found at the smooth, periplasmic end, longer irregular loops are found at the rough, extracellular end. C-terminal residue forms salt bridge with N-terminus.	3.6975e-55
NC_009079.1\|WP_004205322.1\|2236199_2237135_+\|LysR-family-transcriptional-regulator	gnl\|CDD\|176109	cd08417, PBP2_Nitroaromatics_like, The C-terminal substrate binding domain of LysR-type transcriptional regulators that involved in the catabolism of nitroaromatic/naphthalene compounds and that of related regulators; contains the type 2 periplasmic binding fold. This CD includes the C-terminal substrate binding domain of LysR-type transcriptional regulators involved in the catabolism of dinitrotoluene and similar compounds, such as DntR, NahR, and LinR. The transcription of the genes encoding enzymes involved in such degradation is regulated and expression of these enzymes is enhanced by inducers, which are either an intermediate in the metabolic pathway or compounds to be degraded. Also included are related LysR-type regulators clustered together in phylogenetic trees, including NodD, ToxR, LeuO, SyrM, TdcA, and PnbR. This substrate-binding domain shows significant homology to the type 2 periplasmic binding proteins (PBP2), which are responsible for the uptake of a variety of substrates such as phosphate, sulfate, polysaccharides, lysine/arginine/ornithine, and histidine. The PBP2 bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap. After binding their specific ligand with high affinity, they can interact with a cognate membrane transport complex comprised of two integral membrane domains and two cytoplasmically located ATPase domains. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis.	7.67997e-62
NC_009079.1\|WP_004187305.1\|2249951_2250983_+\|hypothetical-protein	gnl\|CDD\|236122	PRK07877, PRK07877, Rv1355c family protein.	5.74738e-30
NC_009079.1\|WP_011832092.1\|2244199_2245426_+\|polyhydroxyalkanoate-depolymerase	gnl\|CDD\|130908	TIGR01849, unnamed_protein_product, polyhydroxyalkanoate depolymerase, intracellular. This model represents an intracellular depolymerase for polyhydroxyalkanoate (PHA), a carbon and energy storing polyester that accumulates in granules in many bacterial species when carbon sources are abundant but other nutrients are limiting. This family is named for PHAs generally, rather than polyhydroxybutyrate (PHB) specificially as in Ralstonia eutropha H16, to avoid overcalling chemical specificity in other species. Note that this family lacks the classic GXSXG lipase motif and instead shows weak similarity to some [Fatty acid and phospholipid metabolism, Degradation].	3.90884e-109
NC_009079.1\|WP_004187137.1\|2253191_2253641_-\|CBS-domain-containing-protein	gnl\|CDD\|341411	cd17775, CBS_pair_bact_arch, Two tandem repeats of the cystathionine beta-synthase (CBS pair) domains present in bacteria and archaea. The CBS domain, named after human CBS, is a small domain originally identified in cystathionine beta-synthase and is subsequently found in a wide range of different proteins. CBS domains usually occur in tandem repeats. They associate to form a so-called Bateman domain or a CBS pair based on crystallographic studies in bacteria. The CBS pair was used as a basis for this cd hierarchy since the human CBS proteins can adopt the typical core structure and form an intramolecular CBS pair. The interface between the two CBS domains forms a cleft that is a potential ligand binding site. The CBS pair coexists with a variety of other functional domains and this has been used to help in its classification here. It has been proposed that the CBS domain may play a regulatory role, although its exact function is unknown. Mutations of conserved residues within this domain are associated with a variety of human hereditary diseases, including congenital myotonia, idiopathic generalized epilepsy, hypercalciuric nephrolithiasis, and classic Bartter syndrome (CLC chloride channel family members), Wolff-Parkinson-White syndrome (gamma 2 subunit of AMP-activated protein kinase), retinitis pigmentosa (IMP dehydrogenase-1), and homocystinuria (cystathionine beta-synthase).	1.39507e-50
NC_009079.1\|WP_004187792.1\|2250979_2252812_+\|STAS-domain-containing-protein	gnl\|CDD\|223732	COG0659, SUL1, Sulfate permease and related transporters (MFS superfamily) [Inorganic ion transport and metabolism].	2.60835e-107
NC_009079.1\|WP_004187216.1\|2240016_2242290_-\|pyridine-nucleotide-disulfide-oxidoreductase	gnl\|CDD\|369639	pfam07992, Pyr_redox_2, Pyridine nucleotide-disulphide oxidoreductase. This family includes both class I and class II oxidoreductases and also NADH oxidases and peroxidases. This domain is actually a small NADH binding domain within a larger FAD binding domain.	7.15563e-57
NC_009079.1\|WP_011204697.1\|2238047_2239706_+\|GMC-family-oxidoreductase	gnl\|CDD\|225186	COG2303, BetA, Choline dehydrogenase and related flavoproteins [Amino acid transport and metabolism].	4.76839e-37
NC_009079.1\|WP_004187710.1\|2247626_2249429_+\|bifunctional-aminoglycoside-phosphotransferase/ATP-binding-protein	gnl\|CDD\|225098	COG2187, COG2187, Uncharacterized protein conserved in bacteria [Function unknown].	9.00049e-75
NC_009079.1\|WP_004553972.1\|2245767_2247552_+\|ribonucleotide-reductase	gnl\|CDD\|180772	PRK06948, PRK06948, ribonucleotide reductase-like protein; Provisional.	0
NC_009079.1\|WP_011204701.1\|2254815_2255250_-\|Hsp20/alpha-crystallin-family-protein	gnl\|CDD\|223149	COG0071, IbpA, Molecular chaperone (small heat shock protein) [Posttranslational modification, protein turnover, chaperones].	2.04683e-32

>NC_009079.1|WP_004187469.1|2242422_2242818_-|conjugal-transfer-protein-TraR
MAAFDEHQLQVLGALLRACRQALQADVRAGERQRADEPYANLAGPAPDEGDEANADLFVDVDHALLGMKLAELRDVDAALQRIARRDYGCCADCGQPIAYERLLARPTALRCAPCQRAHERRFATQPRPSL
>NC_009079.1|WP_004187216.1|2240016_2242290_-|pyridine-nucleotide-disulfide-oxidoreductase
MREFDYLLVGGGIASVTAARTLRGEDASASIAILCGEPVLPYQRPPLSQEWLMGAVQPASITLHDAAFYAAQRIDIALGVRAEQLDRAKRIVRTSSGATFRYGKLLIATGASAKAPALPGFGLDGVHVLHTFAQAQALKDAAAHARRATVLGGGFLGVEIAATLQALGLQVTLVERAPGVMPSLRAPALGGHFEALCRARGIDVLTRCEVRRVLGAQCVEAVETSDGGTRPCDLFVAAVGVTPNCGWLDGSGLALGDGVEVDAFLQTADPDVFAAGDVAHFDDPIFGVRRRIEHWDNAVRQGRIAARNMLGHRLPYRDVSIFYGSVFGLSYNLLGYPVGATETIERGAFDEASYMQLYLADDVLRAAFTIDRPAVEIAALNDAIRLHVNVAAHKMKLSDPNYPLDKLPVQTILILQGGGALGAFECGAVKALEQHGVRPDVISAVSIGAFNGAIVASHPKGATKALEAFWRELSIALPLPYESQWREAWLSSYVLSFGVPNFLKPQWSQLGFDADRLRAKWTSFFDATAIEQLIARYVDFDSLGMSPTRLLIGAVDVETGEPRIFDSYVDRLSPAHVLASGSLPPGMPWTVVDGRPYWDGGVVSNSPLDLVIARCGQIGGRVFIVDLFSGSKALPTNLVEVMLRREEIAYMDRVRNDLRFEEYASDFRDLVDGILAHVDAPSANEIRQQPLYIRLMGNRAAIDIARITLNREGRLSFIEDYDFSSDAIAQLQQQGYDAALVALANGRSRRRRGRRRA
>NC_009079.1|WP_011204697.1|2238047_2239706_+|GMC-family-oxidoreductase
MKQQSYDYDYVVVGSGFGGSVSALRLSEKGYRVLVIEQGRRWTPENLPESTWNLSRWQWRPALGLHGFFSMRFFRHVVVLHGNAVGGGSITYANTLLVPPNKVWREGTWAGLEDWERVMPAHYATAKRMLGVVTNRRMDAADFRLKDMAKLIGVEKSFYPTEVGVFFGDDADAPGTRYADPYFGGAGPERTSCIGCGGCMVGCRHGAKNTLDRNYLYLAERLGAQVREQTKVVDVRPLDARADGAAGYAVEAVSLAAGARGAKSRLTCRGVVFAASSLGTQDLLMRLKEKGSLPRLSDALGKRVRTNAESLIGVRFPKSRVDLSKGVAIGSGIYIDEHTHIEATRYPSGSDTMGLLTTVLTRGAPGGLRVLVWLGALAKLVLTRPLSAWRMIDPRGFARETMIFLCMQTLEGHLTMRLKRRWFWPFSKQLATSGAKIPAYIPAANDFAQKAARALGGVPMTSLTEILLNVPMTAHCMGGAAMARDARDGVCDGRSRVFGYRNMYVCDGSVLGANLGVNPSLTITALAEHAMSHVPAAREQRWDSTAETPVAA
>NC_009079.1|WP_011204696.1|2237316_2237748_+|hypothetical-protein
MHQERRKRNADRHGTHPYDADSRAAPREAPRFEHEPKKQRDAAQHEVDRDRAAREIHERIEHKARPDVRRAERPISQDVAQTPIGAAGAISPSTARSIFLEIGLALAGRPIQVRRNRAPFTHGTPRRRPARGPTARTASPAPV
>NC_009079.1|WP_004205322.1|2236199_2237135_+|LysR-family-transcriptional-regulator
MIQNLRQLDLNLLLVFDALMQEQNLSRAAIRLHMSQPAVSNALTRLRQQLGEPLFTRTARGMTPTAQARTLYEPVRQALYLLQIGLGPQADFEPDTHHLFKLSMNDYGQTVLLPDLLAHIKSRAPNVMLSVQSDDAGSIPAQLTTGTLDLAIDYLHFDNPELCYEPLHEEHLVVIGRAGHPAFAGGLALRGYEESGHVSIQPRDRRGSPLEIVLGSARVRRVVHLQVPHYLTIPALVAKSDLLGTIPRRLAERFADVYALQIAPLPIDIAPIQVSLIWHRQQDAQPGLRWLREQVVLTHRAIIGCGEHAPA
>NC_009079.1|WP_009927403.1|2235962_2236073_-|hypothetical-protein
MQSTGSFDISARRMIEFRSVNKSNHDCPLEKSSGLL
>NC_009079.1|WP_004200700.1|2234786_2235902_-|hypothetical-protein
MTQDVTVFRARYRASVHPRYNAWLHGGFVLAYGCAAIAFFLKDVARVSAVQWASVPAAFLLFNWLEFTVHRHVGHVKRRFGAMFYRRHTGDHHSFFANEQIAYREARDWRVILFPAWLIVVFSLGLFALHAVLGRFDANVAGLFASTMLGGYLLYECVHACEHLPDAHPLAKWPWIRQMRVLHRVHHRDALMRSCNFDVIWPLMDWLHGTLRWSEAPGADMSTRMRHEIDIACAGADVLAYASDASRWPEWHPSSLRVDGPAGSLAAGSRFDEDVRAAGRVDRLHWDVVRNEPGVMWQARAANTAGSLRILLTYECSGGPRGARFVRTLHYHSPNPLLRLANALVMRGRVERESAYSLTLLKRRLEAARDA
>NC_009079.1|WP_004196898.1|2234011_2234452_+|SRPBCC-family-protein
MKQQRIEIAEEFDAPVHQVFRFFSEHENLKSIFSPAKIRRISDGEPARNGVGSAREMRVPGAPPFVETVTAYQENELIEYRITRGSPLRDHLGVMRFVPIDERRTYFHYVITFEGKVPFVAPVVRHVLEGSIRRGLGKVATRRLWG
>NC_009079.1|WP_009950893.1|2233620_2233926_-|hypothetical-protein
MRHDSRLRCTRDDDDIDQCHRQSGRSPLDAEPNRGCAARRLRASGGRRPRGANTEPRRRKPHARVIRQRSWRAARTRPCRRFSAACGRFGQAMARRARPPA
>NC_009079.1|WP_011204695.1|2232962_2233289_+|hypothetical-protein
MRHACRACGPRVRRTRFCAMRKRSETHGRSLSLSLAHRATDARCARCPHSRHELCTRARAPARERRRCIASRISLITTINFRAVAFRPRLPKHYIDRWNHRSAGTPAA
>NC_009079.1|WP_011832092.1|2244199_2245426_+|polyhydroxyalkanoate-depolymerase
MLYAWLEAQREFFRACQPWAGAAQRAGAGARPAGWPTWGPMARAADAVPAPPPFAIASIEIDGAAVPVDECVVDDTPFCALRKFSRRLRGDAAARPAVFLCTPLAGHHAVMLRETVETILATRDVYVTDWRNARDVPPEAGAFGLDDYVCTLERFVAGAAGDGLHMMAVCQATVPALAAVALLGGPVDTRSHPTLIDRFALEHDLDWFRRTAIDIVPPPYAGAGRRVYPGFIQHAAIIVAHPQRRASLESRYWTAWMTGDFAAAARCLREMNEYGAVLDMTERYFLDTIRVIFHERLLAQGRWSIGRRLVAPRRLTRTALCTIEGGRDDIAGAGQTHAAHALCDAVPDAVRERITEPDCDHYDLFLGPRWRRTIHPALDAFWTRAEAARAAAGEPRPTAERAERRIAH
>NC_009079.1|WP_004553972.1|2245767_2247552_+|ribonucleotide-reductase
MIGDMDDQPICDAVFADRYALPGEHSRAQACARVARALALAEPMATRSGAARRFYRNLLNGAFGAGRIMARAGAAPDQTMASCFVHPIRAPAALTRFHPNLDEALDEARLALAMGADIGYDFSAIPPAGARPDADHPDSPGVCAALDRFDRIGTQAGERDGRRRAQLAVLRCDHPDLLAFAAAKHRHAGRHARWTTLELAVAATDAFMQAVEQDLPWTLRHTAPPRDAPGGALPGADGAWTYASVPARHVWREIVSAARDGAGPGLVFVDAIDAADPLRGRERIDATSPCGAQPLPPYGSAMLGAIDLSRFVRNPFGAGGEPRFDFAAFDTAVRIEVRLLDNALDVTRWPLAAHARESYQKRRIGVGVTGLADMLAMMRLRYDSPAAREMARYIASDLRHHAYAASAELAAERGAYPLCDRHAHLDALRAGPPLPHAVCHAIERDGLRHSHLTSFAPVIGVSLAFGDHCSPGIEPARAWIEHRPVRAGAAGAPGMRAENHAHRLFRSLRGERAALPDYFATDADVAPGERLAMRVALQPYVDAGIDNTLTLANHYSLEEVNALLFAAWRAKLKSVAIRRADLARDAQPSDDDGV
>NC_009079.1|WP_004187710.1|2247626_2249429_+|bifunctional-aminoglycoside-phosphotransferase/ATP-binding-protein
MTTGAVAARRLPRRGTARGRRAPSRAFTIHGGDEMRRSRPPKPAKPAAVRRRPHGAARAHAIRGNGPQRRAVRERAARRLSRDIDAALRRASTYPHPAGPIVRIETHLSVVYLVGRFAYKRLKPFDFGFANFTELAARRRACEAELALNRPLAAPIYLAAGPLVRRARGLRLFGAGAAVDHVVRMRRFDERMLFSRLLARGALDAADIDAAATRLAAYHLHAPRDIPRRAYGSARELRRQLDDMLAPLERALGAALPASLRAWCVRRCDELAAHLDARRADGYVRACHGDLHLNNVVKRGRDALMFDCIDFDDALRWIDVINDLSFLLMDLHAHDRAALAHRLLNRWLDETGDFAGLAALPLYVAYRALVRALVATMRAGGDAAARAARIERARRYVDVAAHAARARRPCLLLCHGYSGSGKSVASRALADVSGAIRLSSDSERKRARPFAAVDARPLPASAYTPQQIDAQYERLRALARDVLRAGYTALVDATFLSHARRARFFALARELGVPVYVLDFHASRACLERRVDARAAARDDRSDAGAAVLATQRASADPLDADERARTIGFDTDVPLATLRSAGYWRPVLDAARVDAQATR
>NC_009079.1|WP_004187305.1|2249951_2250983_+|hypothetical-protein
METSPLKTTTPEAIPPFNPSASVEDKLRLAIHYAILAPSSHNTQPWRFMVGDGSVMLCADRLRALSVVDPYDRELLISCGAALLNLRVALSRFGFAYVIDMFPSPSDPDVIALVRLDPHGYHDESLVPLFDAILERVTTRTPYANEAVPCDVQRALVDAGAAEGAEIACVDAPHALDEIAELIADADRLQFADPRFRRELANWVHPRRHDDGMPAFAAGVPALLDFATPVVASAIRTFDLGGGLAAMHHKLVDGSPLIVGISTASDDRDAWVATGQALERVLLVAAAAGLTASYLNQPIEIDALRERLRPLLHVDAHPQLLLRIGRGPVVAHAPRRPLMDVVS
>NC_009079.1|WP_004187792.1|2250979_2252812_+|STAS-domain-containing-protein
MTERERAARGRNDARRGGGDSGGDDEAWRRWLPGIATLRTYRRAWLARDLYAGVALTAVLVPVGMSYAQAAGLPVIAGLNASIAALVGYAIFGPSRILVLGPDSALAALIAGAIAPLAHGEPAHAVALAAALALMSGGFCVLAGLLKLGFVTDLLSKPIQYGYLNGLALTLIASQLPSLLGTVPLGGTFVDQVASLAATVAQGRIDFASLALGGGCLAGIALLRRVAPAWPGMLIAVAGASIVAAWLGAAPDAGGAHAHVAYAHVANAHVALVGSLAGTLPPLGLPSISLADASRLIAGALAIAMVSVADISVLSHVFAQHDGSETDRNQELCALGAANLLAGMLRGCAVSSSASRTPVALAAGARTQLTSLVAAACIALLLIAPTLLARVPLAALAAVVVYSANALVDVRAIVRLYRVRRGECAVSVLCFAGVVLLGVVPGILLAVGLSLLSFVWRAWHPYDAVLGRVEGMHGYHDVSRHPGATLTRGLVAFRWDAPLFHANATIFRDHVRDAIAEAGAPVRCVVIAAEPITDVDVTAADMLATLRDELAARRIALVFAEMKGPVKDRLRTYGLFEKIGADHFFPTVTDAIEHFTRMRKDVATARRARR
>NC_009079.1|WP_011204700.1|2252844_2253219_+|hypothetical-protein
MRARAPIRLGGSARLRSVDDDGAGAQAIEAVRRRHGIGHHDAVSVNAAQAARLRAVARTPNCALDRLDAARFAALRIDDVDISVAVALGIDINVAFPLDIDIDATRRETRRDDSIRQSRAFSSK
>NC_009079.1|WP_004187137.1|2253191_2253641_-|CBS-domain-containing-protein
MNAAEICTREVVACRRTDTVLDAAHLMRDRHVGDLIVVDDAGHAHAPVGMLTDRDIVLSLIAKEVDPAALFVGEIMSAPAAVVHEHDSLWTIAQRMRLTGVRRMPVVNADGALVGMVSVDDLLASVAALFDEIASISRRQIHFEEKARD
>NC_009079.1|WP_004200705.1|2254094_2254748_+|SagB/ThcOx-family-dehydrogenase
MSDPELLTYQPIAVALPGPAEAGAPAVIDLPPPDLGAGLPLMSALSLRASTREFSSAALAPTTLGELLWAADGVNRPTTGGRTAPSAHAFNEIDIYAALPDGVYRYDAALHRLLLKHAVDARNLTGYQDFVGAAPLDLIYVVRMSRLLSMPKPLRETFSAVAAGAIAQNVALYCASTGLGCVVRGWINHRLLAEALSLNEDELPILAQTVGKPAAHP
>NC_009079.1|WP_011204701.1|2254815_2255250_-|Hsp20/alpha-crystallin-family-protein
MSNVTRYDPFSLEPVSDLFRGLFRPLRGIADADDEKLASMKIDVTENDQAYAVKAELPGVDKNDINVQIDGNTVSISAKVERNKELKEGERVIRRERYSGEFARTFSLANELDRDAASAQYQDGVLSLTLPKKASSEKKKLTIG
>NC_009079.1|WP_011204702.1|2255655_2256783_-|porin
MNAKSIAAAALAVAQAGLAHAQSSVTLYGALDAGVLWQNTSAASFSPTAPNTGAVVRFKDGGVYSSLWGIKGTEDLGGGYRVNFRLQGAFDGGTGKFGLSDAPGAVAAFNQIATLGVSGPFGTFNAGRQIVPMIYAMADTDVRAARFFGSVLTAWLGLNTAAGWPGNSTNAPIGALYDSDALVYQSPAFGGASLALEYAPGGVPGGVQRGARASIVLKYASNALNLAAVYYNGHDTNPAPGASATGLDNNRFVYVGAQYKLKDVAVSASYGNGRNPARGDRVNLDMFAFGLGYRVSPFFRVSSGVYYLKDRNRSANRSTSIVLGADYELSKHTTLYAQGGRVDNRGTMAQMLAYGQPVAPGLATTAAMLGMRHSF

You can click texts colored in the table to view more detailed information

Click the colored protein region to show detailed information

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

265468 : 317737

Leptospira_phage(25.0%)

portal,transposase,integrase

attL 289912:289931|attR 307852:307871

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_004190269.1\|265468_266473_+\|transposase	transposase	NA	NA	NA	NA
WP_004195664.1\|268239_268383_+	hypothetical protein	NA	NA	NA	NA
WP_004190833.1\|268470_269550_+	putative membrane protein	NA	NA	NA	NA
WP_038802950.1\|269615_270735_+\|transposase	IS3 family transposase	S5WIU1	Leptospira_phage	3.6e-49	39.5
WP_004190721.1\|270763_271651_-	hypothetical protein	NA	NA	NA	NA
WP_011204313.1\|271833_272196_-	hypothetical protein	NA	NA	NA	NA
WP_004533441.1\|272390_273245_-	AraC family transcriptional regulator	NA	NA	NA	NA
WP_045597094.1\|273307_273934_+	LysE family translocator	NA	NA	NA	NA
WP_009934974.1\|273917_274103_+	hypothetical protein	NA	NA	NA	NA
WP_004529060.1\|274175_274613_-	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_004190743.1\|274838_276077_+	alpha-hydroxy-acid oxidizing protein	NA	NA	NA	NA
WP_004200616.1\|276141_276624_-	YbaK/EbsC family protein	NA	NA	NA	NA
WP_004190582.1\|277881_279525_+	DUF3459 domain-containing protein	NA	NA	NA	NA
WP_004553597.1\|279683_280274_-	thiamine phosphate synthase	NA	NA	NA	NA
WP_004190954.1\|280309_281650_-	HlyC/CorC family transporter	NA	NA	NA	NA
WP_004190659.1\|281735_282515_-	sensor histidine kinase	NA	NA	NA	NA
WP_004190540.1\|282607_283528_-	DMT family transporter	NA	NA	NA	NA
WP_004190343.1\|283594_284470_-	LysR family transcriptional regulator	NA	NA	NA	NA
WP_004190990.1\|284567_284951_+	tautomerase family protein	NA	NA	NA	NA
WP_011204315.1\|285004_287071_+	CHAD domain-containing protein	NA	NA	NA	NA
WP_011204316.1\|287165_287954_+	LysR family transcriptional regulator	NA	NA	NA	NA
WP_011204318.1\|288342_288519_-	hypothetical protein	NA	NA	NA	NA
WP_004190506.1\|288497_289199_-	ATP-binding cassette domain-containing protein	G9BWD6	Planktothrix_phage	2.9e-20	32.3
WP_004190258.1\|289200_289875_-	molybdate ABC transporter permease subunit	NA	NA	NA	NA
WP_004195689.1\|289887_290688_-	molybdate ABC transporter substrate-binding protein	NA	NA	NA	NA
289912:289931	attL	NA	NA	NA	NA
WP_004204469.1\|291128_291827_-	phosphatase PAP2 family protein	NA	NA	NA	NA
WP_004195691.1\|292122_293226_+	PHB depolymerase family esterase	NA	NA	NA	NA
WP_004190391.1\|293322_293481_+	DUF3563 domain-containing protein	NA	NA	NA	NA
WP_011832128.1\|293593_294013_-	organic hydroperoxide resistance protein	NA	NA	NA	NA
WP_004190487.1\|294150_294603_-	MarR family transcriptional regulator	NA	NA	NA	NA
WP_004190292.1\|294599_295109_-	hypothetical protein	NA	NA	NA	NA
WP_004190835.1\|295105_295918_-	hypothetical protein	NA	NA	NA	NA
WP_004190439.1\|295908_296904_-	homoserine kinase	NA	NA	NA	NA
WP_004190726.1\|296997_297396_-	hypothetical protein	NA	NA	NA	NA
WP_004190957.1\|297551_299078_+	AMP nucleosidase	NA	NA	NA	NA
WP_004195697.1\|299161_299848_-\|integrase	tyrosine-type recombinase/integrase	E5E3N4	Burkholderia_phage	3.3e-93	81.6
WP_009950031.1\|299844_300132_-\|portal	phage portal protein	K4NZV0	Burkholderia_phage	6.4e-43	94.4
WP_004529037.1\|300377_300515_+	hypothetical protein	NA	NA	NA	NA
WP_096325434.1\|300688_301809_-\|transposase	IS3 family transposase	S5WIU1	Leptospira_phage	3.6e-49	39.5
WP_009950024.1\|303541_303715_-	hypothetical protein	NA	NA	NA	NA
WP_004203322.1\|303713_303977_+	hypothetical protein	NA	NA	NA	NA
WP_011204319.1\|303901_304078_+	hypothetical protein	NA	NA	NA	NA
WP_004190352.1\|304412_304904_-	DUF523 domain-containing protein	NA	NA	NA	NA
WP_004190916.1\|305563_305848_-	hypothetical protein	NA	NA	NA	NA
WP_004190924.1\|305999_306269_-	hypothetical protein	NA	NA	NA	NA
WP_004530319.1\|306265_307015_-	TIGR00730 family Rossman fold protein	A0A1D8KUT5	Synechococcus_phage	5.6e-22	37.8
WP_004190446.1\|307016_309797_+	DNA polymerase I	S5M8J1	Bacillus_phage	2.9e-71	30.0
307852:307871	attR	NA	NA	NA	NA
WP_004190401.1\|310115_311498_+	NAD(P)/FAD-dependent oxidoreductase	NA	NA	NA	NA
WP_038763983.1\|311838_313632_-	membrane protein	NA	NA	NA	NA
WP_009934941.1\|313806_313899_+	hypothetical protein	NA	NA	NA	NA
WP_004195712.1\|313920_314193_+	hypothetical protein	NA	NA	NA	NA
WP_004190499.1\|314345_315221_+	dienelactone hydrolase family protein	NA	NA	NA	NA
WP_004190656.1\|315279_316149_-	sulfurtransferase	NA	NA	NA	NA
WP_004191998.1\|316273_317737_-\|transposase	IS1182-like element ISBma2 family transposase	A0A1X9I5T2	Streptococcus_phage	8.8e-80	38.6

DBSCAN-SWA_2

386536 : 436218

Leptospira_phage(25.0%)

plate,transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_004190585.1\|386536_387940_+\|plate	type VI secretion system baseplate subunit TssK	NA	NA	NA	NA
WP_004190689.1\|387955_389272_+	DotU family type VI secretion system protein	NA	NA	NA	NA
WP_004190681.1\|389274_392904_+	type VI secretion system membrane subunit TssM	NA	NA	NA	NA
WP_004203277.1\|392909_393806_+	type VI secretion system-associated protein TagF	NA	NA	NA	NA
WP_004190273.1\|393790_394018_-	hypothetical protein	NA	NA	NA	NA
WP_004190797.1\|394016_396614_+	protein kinase	M1I231	Acanthocystis_turfacea_Chlorella_virus	5.0e-09	26.6
WP_004190988.1\|396666_397746_+	type VI secretion system protein TssA	NA	NA	NA	NA
WP_004190671.1\|397808_398387_+	type VI secretion system contractile sheath small subunit	NA	NA	NA	NA
WP_004190849.1\|398379_399888_+	type VI secretion system contractile sheath large subunit	NA	NA	NA	NA
WP_004190698.1\|399947_400439_+	type VI secretion system tube protein Hcp	NA	NA	NA	NA
WP_004196148.1\|400457_401018_+\|plate	type VI secretion system baseplate subunit TssE	NA	NA	NA	NA
WP_004190509.1\|401022_402894_+\|plate	type VI secretion system baseplate subunit TssF	NA	NA	NA	NA
WP_004190820.1\|402890_404369_+\|plate	type VI secretion system baseplate subunit TssG	NA	NA	NA	NA
WP_004203276.1\|404347_407002_+	type VI secretion system ATPase TssH	K4FB40	Cronobacter_phage	2.3e-78	30.8
WP_004203275.1\|406998_409203_+	type VI secretion system tip protein VgrG	A0A077K8Q4	Ralstonia_phage	9.6e-46	29.9
WP_004196151.1\|409277_409931_+	hypothetical protein	NA	NA	NA	NA
WP_011204338.1\|409890_410919_+	RHS repeat protein	NA	NA	NA	NA
WP_038802950.1\|410946_412067_-\|transposase	IS3 family transposase	S5WIU1	Leptospira_phage	3.6e-49	39.5
WP_045589205.1\|411966_412728_-	acyltransferase family protein	NA	NA	NA	NA
WP_011204340.1\|412740_413721_-	class I SAM-dependent methyltransferase	NA	NA	NA	NA
WP_004190776.1\|414237_415662_+	cytosine permease	NA	NA	NA	NA
WP_004190245.1\|415658_416597_+	NAD-dependent protein deacetylase	S5M4R0	Bacillus_phage	1.4e-14	25.3
WP_011204341.1\|416622_417237_+	DUF938 domain-containing protein	NA	NA	NA	NA
WP_004190588.1\|417560_417704_-	hypothetical protein	NA	NA	NA	NA
WP_004190614.1\|417692_419108_+	NADP-dependent phosphogluconate dehydrogenase	M4QQM4	Ostreococcus_lucimarinus_virus	2.1e-41	30.2
WP_011204342.1\|419306_419639_+	DUF4148 domain-containing protein	NA	NA	NA	NA
WP_011204343.1\|420077_420395_+	cupin domain-containing protein	NA	NA	NA	NA
WP_011204344.1\|420673_421438_+	peptidoglycan DD-metalloendopeptidase family protein	NA	NA	NA	NA
WP_004190805.1\|421568_422204_-	hypothetical protein	NA	NA	NA	NA
WP_004190603.1\|422472_423009_+	cytochrome b	NA	NA	NA	NA
WP_004190837.1\|423169_423565_+	DUF2946 domain-containing protein	NA	NA	NA	NA
WP_004190808.1\|423652_425890_+	TonB-dependent copper receptor	NA	NA	NA	NA
WP_004196164.1\|426240_427266_+	triacylglycerol lipase	NA	NA	NA	NA
WP_004190433.1\|427310_428345_+	lipase secretion chaperone	NA	NA	NA	NA
WP_004196166.1\|428446_429967_-	PLP-dependent aminotransferase family protein	NA	NA	NA	NA
WP_004190757.1\|430084_431185_+	ABC transporter ATP-binding protein	G3M9Y6	Bacillus_virus	5.2e-24	31.5
WP_004190781.1\|431259_432306_+	ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_004196172.1\|432406_433666_+	ABC transporter permease	NA	NA	NA	NA
WP_038802950.1\|435097_436218_-\|transposase	IS3 family transposase	S5WIU1	Leptospira_phage	3.6e-49	39.5

DBSCAN-SWA_3

1613197 : 1656654

Agrobacterium_phage(20.0%)

plate,transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_011857826.1\|1613197_1613659_+\|plate	type VI secretion system baseplate subunit TssE	NA	NA	NA	NA
WP_004200971.1\|1613695_1615438_+\|plate	type VI secretion system baseplate subunit TssF	NA	NA	NA	NA
WP_004200970.1\|1615425_1616448_+\|plate	type VI secretion system baseplate subunit TssG	NA	NA	NA	NA
WP_011857827.1\|1616434_1619482_+	type VI secretion system ATPase TssH	A0A223W0B1	Agrobacterium_phage	4.5e-78	29.5
WP_004184913.1\|1619508_1622532_+	type VI secretion system tip protein VgrG	A0A077K8Q4	Ralstonia_phage	1.2e-22	24.8
WP_004206518.1\|1622557_1625200_+	DUF2169 domain-containing protein	NA	NA	NA	NA
WP_004206517.1\|1625217_1626282_+	pentapeptide repeat-containing protein	NA	NA	NA	NA
WP_004200968.1\|1626278_1627040_+	DUF3540 domain-containing protein	NA	NA	NA	NA
WP_004200966.1\|1627068_1627461_+	DUF4150 domain-containing protein	NA	NA	NA	NA
WP_004200965.1\|1627470_1628268_+	type VI secretion system lipoprotein TssJ	NA	NA	NA	NA
WP_004206515.1\|1628300_1629698_+\|plate	type VI secretion system baseplate subunit TssK	NA	NA	NA	NA
WP_004184888.1\|1629694_1630360_+	DotU family type IV/VI secretion system protein	NA	NA	NA	NA
WP_004266677.1\|1630371_1634331_+	type VI secretion system protein ImpL	NA	NA	NA	NA
WP_011807503.1\|1634863_1636288_+	peptidase	NA	NA	NA	NA
WP_004201911.1\|1636247_1636493_-	hypothetical protein	NA	NA	NA	NA
WP_004551882.1\|1636451_1636745_+	hypothetical protein	NA	NA	NA	NA
WP_004528803.1\|1636749_1637382_+	GTP cyclohydrolase I	A0A0P0HSD2	Acinetobacter_phage	9.9e-20	30.6
WP_096325434.1\|1637975_1639095_+\|transposase	IS3 family transposase	S5WIU1	Leptospira_phage	3.6e-49	39.5
WP_004200959.1\|1639170_1640091_+	metal-dependent hydrolase	NA	NA	NA	NA
WP_004201904.1\|1640208_1640706_+	hypothetical protein	NA	NA	NA	NA
WP_004200955.1\|1641127_1642444_+	acyl-CoA dehydrogenase	NA	NA	NA	NA
WP_004266343.1\|1642837_1643134_-	H-NS histone family protein	NA	NA	NA	NA
WP_004200952.1\|1643278_1643521_+	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_011204409.1\|1643500_1644013_-	hypothetical protein	NA	NA	NA	NA
WP_004201902.1\|1644116_1645460_-	amino acid permease	NA	NA	NA	NA
WP_011204408.1\|1645496_1645964_+	hypothetical protein	NA	NA	NA	NA
WP_004200946.1\|1646369_1647239_-	hypothetical protein	NA	NA	NA	NA
WP_004184941.1\|1647254_1648031_-	SDR family NAD(P)-dependent oxidoreductase	NA	NA	NA	NA
WP_011204407.1\|1648167_1648353_+	hypothetical protein	NA	NA	NA	NA
WP_004200944.1\|1648435_1649644_-	MFS transporter	NA	NA	NA	NA
WP_011204406.1\|1649832_1650879_-	cytochrome P460	NA	NA	NA	NA
WP_011204405.1\|1651048_1651195_+	hypothetical protein	NA	NA	NA	NA
WP_004200942.1\|1651345_1652386_-	zinc-dependent alcohol dehydrogenase family protein	NA	NA	NA	NA
WP_004200941.1\|1652635_1653475_+	universal stress protein	NA	NA	NA	NA
WP_004200939.1\|1653656_1654151_+	universal stress protein	NA	NA	NA	NA
WP_041277124.1\|1655190_1656654_-\|transposase	IS1182-like element ISBma2 family transposase	A0A1X9I5T2	Streptococcus_phage	8.8e-80	38.6

DBSCAN-SWA_4

1782148 : 1825234

Leptospira_phage(33.33%)

holin,transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_038802950.1\|1782148_1783269_-\|transposase	IS3 family transposase	S5WIU1	Leptospira_phage	3.6e-49	39.5
WP_011204369.1\|1783548_1784664_+	hypothetical protein	NA	NA	NA	NA
WP_011204368.1\|1784594_1785134_-	hypothetical protein	NA	NA	NA	NA
WP_011857835.1\|1785090_1785573_-	cupin domain-containing protein	NA	NA	NA	NA
WP_004200846.1\|1785667_1786282_-	HAD family phosphatase	NA	NA	NA	NA
WP_004200845.1\|1786472_1787177_+	FadR family transcriptional regulator	NA	NA	NA	NA
WP_004184805.1\|1787255_1788146_+	2-hydroxy-3-oxopropionate reductase	A0A077SLF7	Escherichia_phage	7.3e-77	58.1
WP_011857836.1\|1788168_1789560_+	four-carbon acid sugar kinase family protein	A0A077SLJ7	Escherichia_phage	2.5e-84	44.0
WP_004194988.1\|1789556_1790198_+	aldolase	A0A077SK32	Escherichia_phage	9.6e-39	48.1
WP_004201828.1\|1790301_1791624_+	MFS transporter	NA	NA	NA	NA
WP_004184793.1\|1791705_1792482_+	hydroxypyruvate isomerase family protein	NA	NA	NA	NA
WP_004266705.1\|1792509_1793481_+	SDR family oxidoreductase	NA	NA	NA	NA
WP_004194984.1\|1794429_1795122_+	aspartyl/asparaginyl beta-hydroxylase domain-containing protein	S4VR59	Pandoravirus	2.6e-21	36.3
WP_011204366.1\|1795252_1795723_-	hypothetical protein	NA	NA	NA	NA
WP_011204365.1\|1795829_1796012_-	hypothetical protein	NA	NA	NA	NA
WP_004194983.1\|1796002_1796902_-	lipid A hydroxylase LpxO	H8ZJK8	Ostreococcus_tauri_virus	1.4e-32	39.6
WP_004533171.1\|1797291_1798242_-\|holin	choline ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_004199315.1\|1798342_1799341_-	GlxA family transcriptional regulator	NA	NA	NA	NA
WP_004200833.1\|1799463_1800366_-\|holin	choline ABC transporter permease subunit	NA	NA	NA	NA
WP_004533427.1\|1800358_1801528_-	glycine betaine/L-proline ABC transporter ATP-binding protein	G3M9Y6	Bacillus_virus	2.6e-26	33.8
WP_004555731.1\|1802316_1802979_+	NAD(P)H-dependent oxidoreductase	NA	NA	NA	NA
WP_004198711.1\|1803005_1803197_+	hypothetical protein	NA	NA	NA	NA
WP_004198708.1\|1803572_1803788_+	hypothetical protein	NA	NA	NA	NA
WP_004266244.1\|1803886_1804786_+	hypothetical protein	NA	NA	NA	NA
WP_004198701.1\|1805257_1805593_+	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_004184724.1\|1805589_1806069_+	glyoxalase/bleomycin resistance/dioxygenase family protein	NA	NA	NA	NA
WP_004184680.1\|1806103_1806598_+	arsenate reductase ArsC	NA	NA	NA	NA
WP_004266245.1\|1806660_1807731_+	ACR3 family arsenite efflux transporter	NA	NA	NA	NA
WP_038802950.1\|1808300_1809420_+\|transposase	IS3 family transposase	S5WIU1	Leptospira_phage	3.6e-49	39.5
WP_024900894.1\|1818002_1818737_+	hypothetical protein	NA	NA	NA	NA
WP_011326545.1\|1818768_1819458_-\|transposase	IS3 family transposase	NA	NA	NA	NA
WP_009967729.1\|1819901_1820834_-	glycerophosphoryl diester phosphodiesterase	NA	NA	NA	NA
WP_004184834.1\|1822412_1823873_-	ser/threonine protein phosphatase	NA	NA	NA	NA
WP_096325434.1\|1824113_1825234_-\|transposase	IS3 family transposase	S5WIU1	Leptospira_phage	3.6e-49	39.5

DBSCAN-SWA_5

2113218 : 2165960

Organic_Lake_phycodnavirus(25.0%)

plate,transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_073699071.1\|2113218_2114292_-\|plate	type VI secretion system baseplate subunit TssG	NA	NA	NA	NA
WP_004187986.1\|2114303_2116193_-\|plate	type VI secretion system baseplate subunit TssF	NA	NA	NA	NA
WP_004187068.1\|2116223_2116805_-\|plate	type VI secretion system baseplate subunit TssE	NA	NA	NA	NA
WP_004187921.1\|2116791_2117757_-	ImpE/SciE family protein	NA	NA	NA	NA
WP_004188539.1\|2117753_2118500_-	TagK domain-containing protein	NA	NA	NA	NA
WP_004196243.1\|2121964_2122546_+	type VI secretion system contractile sheath small subunit	NA	NA	NA	NA
WP_004188012.1\|2122580_2124080_+	type VI secretion system contractile sheath large subunit	NA	NA	NA	NA
WP_004188308.1\|2124196_2124682_+	type VI secretion system tube protein Hcp	NA	NA	NA	NA
WP_004187276.1\|2124788_2125292_+	type VI secretion system lipoprotein TssJ	NA	NA	NA	NA
WP_004188743.1\|2125313_2126660_+\|plate	type VI secretion system baseplate subunit TssK	NA	NA	NA	NA
WP_011204670.1\|2126733_2128014_+	type VI secretion system protein TssL	NA	NA	NA	NA
WP_004188288.1\|2132137_2132368_+	hypothetical protein	NA	NA	NA	NA
WP_011204671.1\|2132649_2132886_+	hypothetical protein	NA	NA	NA	NA
WP_011204672.1\|2132874_2133225_-	hypothetical protein	NA	NA	NA	NA
WP_011857853.1\|2133337_2134300_+	LysR family transcriptional regulator	NA	NA	NA	NA
WP_004187006.1\|2134542_2135469_-	catecholic dioxygenase	NA	NA	NA	NA
WP_004187502.1\|2135523_2136495_-	quinone oxidoreductase	NA	NA	NA	NA
WP_004187879.1\|2136523_2138392_-	asparagine synthase (glutamine-hydrolyzing)	F2Y1H0	Organic_Lake_phycodnavirus	3.0e-24	25.9
WP_004187705.1\|2138437_2139922_-	Pyoverdin chromophore biosynthetic protein pvcC	NA	NA	NA	NA
WP_004188574.1\|2139947_2140847_-	TauD/TfdA family dioxygenase	NA	NA	NA	NA
WP_004188150.1\|2140843_2141902_-	L-tyrosine/L-tryptophan isonitrile synthase family protein	NA	NA	NA	NA
WP_004187628.1\|2142031_2143252_-\|transposase	ISL3-like element ISBma1 family transposase	A9YX10	Burkholderia_phage	7.8e-239	99.5
WP_011204674.1\|2143558_2143789_-	hypothetical protein	NA	NA	NA	NA
WP_073699120.1\|2143816_2146714_-	glycoside hydrolase family 92 protein	NA	NA	NA	NA
WP_004196252.1\|2146988_2148905_-	hypothetical protein	NA	NA	NA	NA
WP_004187282.1\|2149111_2149261_-	hypothetical protein	NA	NA	NA	NA
WP_004187552.1\|2149346_2149712_-	nuclear transport factor 2 family protein	NA	NA	NA	NA
WP_009922971.1\|2149793_2149904_+	hypothetical protein	NA	NA	NA	NA
WP_004202300.1\|2149851_2150136_-	hypothetical protein	NA	NA	NA	NA
WP_004529705.1\|2150134_2150896_+	SDR family oxidoreductase	NA	NA	NA	NA
WP_004188170.1\|2151440_2152373_+	LysR family transcriptional regulator	NA	NA	NA	NA
WP_004196258.1\|2152525_2153773_+	D-amino acid dehydrogenase	NA	NA	NA	NA
WP_004554722.1\|2153936_2154836_+	glutamate/aspartate ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_004557674.1\|2155036_2155441_+	hypothetical protein	NA	NA	NA	NA
WP_004196262.1\|2155428_2155869_-	hypothetical protein	NA	NA	NA	NA
WP_004188358.1\|2156017_2156314_-	hypothetical protein	NA	NA	NA	NA
WP_004201242.1\|2156370_2157411_-	fatty acid desaturase	NA	NA	NA	NA
WP_080518649.1\|2157541_2157757_-	hypothetical protein	NA	NA	NA	NA
WP_004547820.1\|2157749_2158559_+	PhnD/SsuA/transferrin family substrate-binding protein	NA	NA	NA	NA
WP_004187366.1\|2158900_2159803_-	LysR family transcriptional regulator	NA	NA	NA	NA
WP_004187422.1\|2159982_2161173_+	amidohydrolase	NA	NA	NA	NA
WP_004188653.1\|2162560_2163190_+	porin	NA	NA	NA	NA
WP_004202308.1\|2163383_2164775_+	ATP-dependent RNA helicase DbpA	A0A0N9Q9J4	Chrysochromulina_ericina_virus	2.3e-45	31.7
WP_038802950.1\|2164840_2165960_+\|transposase	IS3 family transposase	S5WIU1	Leptospira_phage	3.6e-49	39.5

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

2. NC_009080

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

119200 : 183516

Leptospira_phage(25.0%)

tRNA,transposase,integrase

attL 134379:134438|attR 182349:183545

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_004189587.1\|119200_119692_+\|tRNA	Cys-tRNA(Pro) deacylase	NA	NA	NA	NA
WP_004189721.1\|119800_120412_+	glycerol-3-phosphate 1-O-acyltransferase PlsY	NA	NA	NA	NA
WP_004189237.1\|120641_121127_-	YajQ family cyclic di-GMP-binding protein	NA	NA	NA	NA
WP_004534288.1\|121263_122313_+	UDP-N-acetylmuramate dehydrogenase	NA	NA	NA	NA
WP_004190177.1\|122505_123435_-	ornithine carbamoyltransferase	M1HWF9	Paramecium_bursaria_Chlorella_virus	4.1e-22	26.7
WP_004534369.1\|123671_124184_+	DUF3579 domain-containing protein	NA	NA	NA	NA
WP_004189743.1\|124412_124691_-	30S ribosomal protein S20	NA	NA	NA	NA
WP_004266891.1\|125095_126646_+	murein biosynthesis integral membrane protein MurJ	NA	NA	NA	NA
WP_004189739.1\|126655_127498_+	tetratricopeptide repeat protein	NA	NA	NA	NA
WP_004189909.1\|127756_128515_-	3-hydroxyacyl-CoA dehydrogenase	NA	NA	NA	NA
WP_004191998.1\|128726_130190_-\|transposase	IS1182-like element ISBma2 family transposase	A0A1X9I5T2	Streptococcus_phage	8.8e-80	38.6
WP_004189292.1\|130348_131959_-	multicopper oxidase family protein	NA	NA	NA	NA
WP_004189626.1\|131971_132154_+	hypothetical protein	NA	NA	NA	NA
WP_004189552.1\|132126_133386_-	NADP-dependent isocitrate dehydrogenase	Q77Z09	Phage_21	5.2e-12	63.0
WP_004189780.1\|133653_134232_+	pseudouridine synthase	NA	NA	NA	NA
134379:134438	attL	NA	NA	NA	NA
WP_038802950.1\|134425_135546_-\|transposase	IS3 family transposase	S5WIU1	Leptospira_phage	3.6e-49	39.5
WP_004189968.1\|135576_136248_-\|integrase	integrase arm-type DNA-binding domain-containing protein	B7SYF8	Stenotrophomonas_phage	1.3e-46	46.1
WP_011203829.1\|136474_136567_-	hypothetical protein	NA	NA	NA	NA
WP_038802950.1\|136961_138082_-\|transposase	IS3 family transposase	S5WIU1	Leptospira_phage	3.6e-49	39.5
WP_004557196.1\|138454_138667_+	hypothetical protein	NA	NA	NA	NA
WP_011203825.1\|138663_139257_-	chorismate mutase	NA	NA	NA	NA
WP_011203824.1\|139782_140259_+	DUF2946 domain-containing protein	NA	NA	NA	NA
WP_004188913.1\|140405_142742_+	TonB-dependent receptor	NA	NA	NA	NA
WP_004554214.1\|142729_144001_+	exo-alpha-sialidase	NA	NA	NA	NA
WP_004203540.1\|143997_144486_+	hypothetical protein	NA	NA	NA	NA
WP_011205188.1\|144772_145120_-	GlsB/YeaQ/YmgE family stress response membrane protein	NA	NA	NA	NA
WP_004550102.1\|145777_146026_-	hypothetical protein	NA	NA	NA	NA
WP_004197792.1\|146194_146671_-	hypothetical protein	NA	NA	NA	NA
WP_004190100.1\|146693_146954_-	hypothetical protein	NA	NA	NA	NA
WP_004186184.1\|147295_148516_-\|transposase	ISL3-like element ISBma1 family transposase	A9YX10	Burkholderia_phage	6.6e-238	99.0
WP_004189384.1\|148863_149880_-	class 1 fructose-bisphosphatase	A0A1V0SKX4	Klosneuvirus	5.4e-52	36.4
WP_004189234.1\|150009_150942_-	LysR family transcriptional regulator	NA	NA	NA	NA
WP_004189599.1\|151058_153353_+	5-methyltetrahydropteroyltriglutamate-- homocysteine S-methyltransferase	NA	NA	NA	NA
WP_004189239.1\|153709_156412_-	aminopeptidase N	NA	NA	NA	NA
WP_004189242.1\|156436_156574_+	hypothetical protein	NA	NA	NA	NA
WP_004189569.1\|156632_157346_+	DUF4136 domain-containing protein	NA	NA	NA	NA
WP_004189913.1\|157679_158252_-	TMEM165/GDT1 family protein	NA	NA	NA	NA
WP_004189253.1\|158248_158659_-	hypothetical protein	NA	NA	NA	NA
WP_004189962.1\|158739_160050_-	guanine deaminase	NA	NA	NA	NA
WP_004189169.1\|160075_161452_-	NCS2 family permease	NA	NA	NA	NA
WP_004189005.1\|161549_162575_-	adenosine deaminase	NA	NA	NA	NA
WP_004189595.1\|162616_163639_-	xanthine dehydrogenase accessory protein XdhC	A0A0P0IKN7	Acinetobacter_phage	1.1e-44	37.8
WP_011203822.1\|163633_163984_+	hypothetical protein	NA	NA	NA	NA
WP_004189653.1\|164147_164657_-	disulfide bond formation protein B	NA	NA	NA	NA
WP_004550105.1\|164765_166142_-	amidase	NA	NA	NA	NA
WP_011203821.1\|166138_166876_-	hypothetical protein	NA	NA	NA	NA
WP_011203820.1\|167008_168079_+	gamma-glutamyl-gamma-aminobutyrate hydrolase	NA	NA	NA	NA
WP_073699190.1\|168289_168514_+	hypothetical protein	NA	NA	NA	NA
WP_004188918.1\|168567_169863_+	MFS transporter	Q6JIH2	Burkholderia_virus	3.2e-65	37.5
WP_011203819.1\|170251_172132_-	tetratricopeptide repeat protein	F2Y1J7	Organic_Lake_phycodnavirus	1.7e-11	32.2
WP_004200810.1\|172279_173896_+	FAD-binding monooxygenase	NA	NA	NA	NA
WP_004195994.1\|174532_177487_-	formate dehydrogenase subunit alpha	NA	NA	NA	NA
WP_004189204.1\|177501_179067_-	formate dehydrogenase beta subunit	NA	NA	NA	NA
WP_004189882.1\|179063_179537_-	formate dehydrogenase subunit gamma	NA	NA	NA	NA
WP_004195993.1\|179667_180774_+	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_004189371.1\|180875_181139_+	hypothetical protein	NA	NA	NA	NA
WP_004200808.1\|181319_182006_-	phospholipid methyltransferase	NA	NA	NA	NA
WP_038802950.1\|182395_183516_-\|transposase	IS3 family transposase	S5WIU1	Leptospira_phage	3.6e-49	39.5
182349:183545	attR	NA	NA	NA	NA

DBSCAN-SWA_2

201395 : 210231

Bacillus_phage(16.67%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_004189214.1\|201395_202796_+	UDP-glucose/GDP-mannose dehydrogenase family protein	A0A127AXI2	Bacillus_phage	2.1e-78	38.3
WP_004203554.1\|202764_203751_+	D-glycero-beta-D-manno-heptose-7-phosphate kinase	A0A2H4N7X4	Lake_Baikal_phage	1.8e-15	26.5
WP_004190173.1\|203809_204802_+	ADP-glyceromanno-heptose 6-epimerase	R9S880	Prochlorococcus_phage	9.1e-28	30.9
WP_004189725.1\|204873_205191_+	competence protein ComE	NA	NA	NA	NA
WP_004204273.1\|205203_205503_+	hypothetical protein	NA	NA	NA	NA
WP_004532363.1\|205514_206417_+	cysteine synthase CysM	A0A1X9I5F1	Streptococcus_phage	1.9e-53	39.9
WP_085962626.1\|206642_207995_-	lytic murein transglycosylase B	NA	NA	NA	NA
WP_004188957.1\|208122_209046_+	histone deacetylase family protein	A0A2K9KZC4	Tupanvirus	8.4e-44	36.5
WP_004190087.1\|209388_210231_-	alpha/beta hydrolase	A7XCB7	Tanapox_virus	7.2e-18	27.2

DBSCAN-SWA_3

233112 : 290795

Streptococcus_phage(16.67%)

transposase,protease

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_004188997.1\|233112_234483_+\|protease	metalloprotease PmbA	NA	NA	NA	NA
WP_004191998.1\|234619_236083_+\|transposase	IS1182-like element ISBma2 family transposase	A0A1X9I5T2	Streptococcus_phage	8.8e-80	38.6
WP_004189313.1\|236211_236715_-	dihydrofolate reductase	A0A0A0PL85	Bacillus_phage	9.6e-26	40.4
WP_080518661.1\|236922_238725_-	sigma-54-dependent Fis family transcriptional regulator	NA	NA	NA	NA
WP_011832229.1\|238986_240264_-	hypothetical protein	NA	NA	NA	NA
WP_004201791.1\|240260_240629_-	hypothetical protein	NA	NA	NA	NA
WP_004195958.1\|240893_241190_-	hypothetical protein	NA	NA	NA	NA
WP_004189039.1\|241151_242537_+	sigma-54-dependent Fis family transcriptional regulator	NA	NA	NA	NA
WP_004189921.1\|242593_243565_+	thymidylate synthase	A0A1V0DY05	Yersinia_phage	2.9e-47	36.1
WP_004191998.1\|243696_245160_+\|transposase	IS1182-like element ISBma2 family transposase	A0A1X9I5T2	Streptococcus_phage	8.8e-80	38.6
WP_004189917.1\|247998_248709_-	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_004197804.1\|249272_249467_+	hypothetical protein	NA	NA	NA	NA
WP_004190145.1\|249654_250161_+	acyl-CoA thioesterase	NA	NA	NA	NA
WP_004189867.1\|250639_252034_-	class II fumarate hydratase	NA	NA	NA	NA
WP_011203828.1\|252036_252222_+	hypothetical protein	NA	NA	NA	NA
WP_038802950.1\|252417_253538_-\|transposase	IS3 family transposase	S5WIU1	Leptospira_phage	3.6e-49	39.5
WP_011857877.1\|253933_255103_+	ABC transporter ATP-binding protein	NA	NA	NA	NA
WP_004194783.1\|255165_255939_+	ABC transporter ATP-binding protein	A0A2H4PQG7	Staphylococcus_phage	4.8e-16	25.6
WP_004185649.1\|255938_256655_+	ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	2.4e-14	26.4
WP_024900363.1\|256951_257620_+	DUF2278 family protein	NA	NA	NA	NA
WP_004186487.1\|257792_258263_-	GNAT family acetyltransferase	NA	NA	NA	NA
WP_004185932.1\|258267_259452_-	acetylornithine transaminase	A0A1V0SKB7	Klosneuvirus	8.6e-25	27.3
WP_004185343.1\|259728_260760_-	CDP-6-deoxy-delta-3,4-glucoseen reductase	NA	NA	NA	NA
WP_073699251.1\|260842_261868_+	NAD(P)-dependent oxidoreductase	NA	NA	NA	NA
WP_011204920.1\|261860_262133_-	hypothetical protein	NA	NA	NA	NA
WP_004185598.1\|262165_262888_-	16S rRNA pseudouridine(516) synthase	NA	NA	NA	NA
WP_004204344.1\|263035_263401_+	copper homeostasis periplasmic binding protein CopC	NA	NA	NA	NA
WP_011832225.1\|263412_264375_-	LysR family transcriptional regulator	NA	NA	NA	NA
WP_004186473.1\|264576_265473_-	LysR family transcriptional regulator	NA	NA	NA	NA
WP_004186242.1\|265594_266491_+	alpha/beta hydrolase	NA	NA	NA	NA
WP_004185849.1\|266693_267383_-	MOSC domain-containing protein	NA	NA	NA	NA
WP_004186540.1\|267397_268294_-	dihydrodipicolinate synthase family protein	NA	NA	NA	NA
WP_004186330.1\|268375_269158_-	aldolase	NA	NA	NA	NA
WP_004185798.1\|269289_269853_+	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_011204067.1\|269937_270384_+	hypothetical protein	NA	NA	NA	NA
WP_038802950.1\|270680_271801_-\|transposase	IS3 family transposase	S5WIU1	Leptospira_phage	3.6e-49	39.5
WP_004194779.1\|271869_273051_-	PLP-dependent aminotransferase family protein	NA	NA	NA	NA
WP_004186089.1\|273111_274020_-	DMT family transporter	NA	NA	NA	NA
WP_004186239.1\|274120_274804_-	VOC family protein	NA	NA	NA	NA
WP_004185957.1\|274954_276409_+	PLP-dependent aminotransferase family protein	NA	NA	NA	NA
WP_009919375.1\|276410_276548_+	hypothetical protein	NA	NA	NA	NA
WP_004185742.1\|276544_278443_+	molecular chaperone HtpG	A0A1B1ISV4	uncultured_Mediterranean_phage	3.0e-120	38.5
WP_004550738.1\|278451_279045_+	chorismate lyase	NA	NA	NA	NA
WP_011204944.1\|279041_279521_+	DNA-deoxyinosine glycosylase	NA	NA	NA	NA
WP_004185567.1\|279771_280701_+	spermidine synthase	NA	NA	NA	NA
WP_004194775.1\|280892_281132_+	DUF3311 domain-containing protein	NA	NA	NA	NA
WP_004186395.1\|281128_282679_+	sodium:solute symporter	NA	NA	NA	NA
WP_004186249.1\|282804_283239_-	VOC family protein	NA	NA	NA	NA
WP_004186409.1\|283604_284558_-	transaldolase	A0A0E3F5V4	Synechococcus_phage	4.3e-11	29.6
WP_011204065.1\|284625_284982_+	hypothetical protein	NA	NA	NA	NA
WP_004186095.1\|284959_286177_-	benzoate/H(+) symporter BenE family transporter	NA	NA	NA	NA
WP_004186167.1\|286260_287436_-	VWA domain-containing protein	NA	NA	NA	NA
WP_004186676.1\|287648_288491_-	MoxR family ATPase	NA	NA	NA	NA
WP_004185759.1\|288724_289084_+	cytochrome c	NA	NA	NA	NA
WP_004194773.1\|289124_289493_+	c-type cytochrome	NA	NA	NA	NA
WP_004187628.1\|289574_290795_-\|transposase	ISL3-like element ISBma1 family transposase	A9YX10	Burkholderia_phage	7.8e-239	99.5

DBSCAN-SWA_4

643408 : 687701

Leptospira_phage(33.33%)

coat,tRNA,transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_038802950.1\|643408_644529_-\|transposase	IS3 family transposase	S5WIU1	Leptospira_phage	3.6e-49	39.5
WP_004193365.1\|644623_645016_+	hypothetical protein	NA	NA	NA	NA
WP_004193170.1\|645275_646589_+	divalent metal cation transporter	NA	NA	NA	NA
WP_011203888.1\|646637_646814_+	hypothetical protein	NA	NA	NA	NA
WP_011203889.1\|647105_647360_-	hypothetical protein	NA	NA	NA	NA
WP_004552605.1\|647444_647753_+	lipoprotein	NA	NA	NA	NA
WP_004193855.1\|648005_648287_-	H-NS histone family protein	NA	NA	NA	NA
WP_009937836.1\|648286_648547_-	hypothetical protein	NA	NA	NA	NA
WP_004192394.1\|648754_649747_-	hydrolase	NA	NA	NA	NA
WP_004196700.1\|649791_650988_-	MFS transporter	NA	NA	NA	NA
WP_009920897.1\|651143_651281_-	hypothetical protein	NA	NA	NA	NA
WP_004196705.1\|651494_652388_+	LysR family transcriptional regulator	NA	NA	NA	NA
WP_004531175.1\|652725_652947_+	hypothetical protein	NA	NA	NA	NA
WP_004542449.1\|653032_653218_+	hypothetical protein	NA	NA	NA	NA
WP_004192149.1\|653204_653750_+\|coat	spore coat protein U domain-containing protein	NA	NA	NA	NA
WP_004191870.1\|653802_654363_+\|coat	spore coat protein U domain-containing protein	NA	NA	NA	NA
WP_004526783.1\|654439_654964_+\|coat	spore coat protein U domain-containing protein	NA	NA	NA	NA
WP_004191504.1\|654981_655821_+	molecular chaperone	NA	NA	NA	NA
WP_004196717.1\|658293_659259_+\|coat	spore coat protein U domain-containing protein	NA	NA	NA	NA
WP_004552891.1\|659669_661751_+	response regulator	A0A1V0SGR3	Hokovirus	1.7e-12	26.8
WP_004192810.1\|661751_662384_+	response regulator transcription factor	NA	NA	NA	NA
WP_004192651.1\|664373_665993_-	DHA2 family efflux MFS transporter permease subunit	NA	NA	NA	NA
WP_004191546.1\|666165_667353_-	HlyD family secretion protein	NA	NA	NA	NA
WP_004196723.1\|667592_667913_-	hypothetical protein	NA	NA	NA	NA
WP_004266854.1\|667971_669165_-	trans-2-enoyl-CoA reductase family protein	NA	NA	NA	NA
WP_004521730.1\|669362_671036_-	acid phosphatase	NA	NA	NA	NA
WP_011203890.1\|671470_672595_+	cytochrome-c peroxidase	NA	NA	NA	NA
WP_004192265.1\|672638_673499_-	M15 family metallopeptidase	NA	NA	NA	NA
WP_004196725.1\|673495_673675_-	hypothetical protein	NA	NA	NA	NA
WP_004193860.1\|675976_676363_+	hypothetical protein	NA	NA	NA	NA
WP_011203891.1\|676390_676864_+	NUDIX hydrolase	A0A2I6PFL2	Proteus_phage	3.7e-19	41.3
WP_004193654.1\|677195_678905_-\|tRNA	glutamine--tRNA ligase/YqeY domain fusion protein	A0A222YZ70	Escherichia_phage	8.8e-188	57.5
WP_011203892.1\|679121_679586_+	hypothetical protein	NA	NA	NA	NA
WP_004204969.1\|679715_680936_-	CoA transferase	NA	NA	NA	NA
WP_004204967.1\|681594_684219_+\|tRNA	alanine--tRNA ligase	A0A1V0SK38	Klosneuvirus	5.5e-80	39.2
WP_004192193.1\|684722_685688_-	LysR family transcriptional regulator	NA	NA	NA	NA
WP_011807697.1\|685834_686551_+	YbfB/YjiJ family MFS transporter	NA	NA	NA	NA
WP_038802950.1\|686581_687701_+\|transposase	IS3 family transposase	S5WIU1	Leptospira_phage	3.6e-49	39.5

DBSCAN-SWA_5

1482718 : 1548488

Streptococcus_phage(36.36%)

transposase,protease

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_004191998.1\|1482718_1484182_+\|transposase	IS1182-like element ISBma2 family transposase	A0A1X9I5T2	Streptococcus_phage	8.8e-80	38.6
WP_004199567.1\|1484290_1484860_-	phasin family protein	NA	NA	NA	NA
WP_004557110.1\|1485529_1486651_+	D-alanyl-D-alanine endopeptidase	NA	NA	NA	NA
WP_004191998.1\|1486770_1488234_-\|transposase	IS1182-like element ISBma2 family transposase	A0A1X9I5T2	Streptococcus_phage	8.8e-80	38.6
WP_004192702.1\|1488490_1490260_-	dihydrolipoyl dehydrogenase	A0A2K5B2C5	Erysipelothrix_phage	6.8e-34	23.8
WP_004193075.1\|1490567_1492157_-	dihydrolipoyllysine-residue acetyltransferase	NA	NA	NA	NA
WP_004199569.1\|1492289_1494986_-	pyruvate dehydrogenase (acetyl-transferring), homodimeric type	NA	NA	NA	NA
WP_011204038.1\|1495129_1497769_+	PAS domain S-box protein	NA	NA	NA	NA
WP_004193928.1\|1497765_1498404_+	response regulator transcription factor	NA	NA	NA	NA
WP_004192825.1\|1498720_1499578_+	bifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase FolD	A0A249XZQ2	Enterococcus_phage	4.1e-37	39.9
WP_011204039.1\|1499815_1500139_+	hypothetical protein	NA	NA	NA	NA
WP_004191126.1\|1500255_1502355_+	M3 family metallopeptidase	A0A1V0SD92	Indivirus	1.7e-39	21.8
WP_009931175.1\|1502584_1503799_-	DNA polymerase IV	NA	NA	NA	NA
WP_004192547.1\|1503739_1504024_+	hypothetical protein	NA	NA	NA	NA
WP_004193983.1\|1504509_1505790_+	NarK/NasA family nitrate transporter	NA	NA	NA	NA
WP_004192248.1\|1505833_1507219_+	NarK family nitrate/nitrite MFS transporter	NA	NA	NA	NA
WP_004193149.1\|1507469_1511195_+	nitrate reductase subunit alpha	NA	NA	NA	NA
WP_004193619.1\|1511191_1512745_+	nitrate reductase subunit beta	A0A077SL61	Escherichia_phage	2.9e-20	46.5
WP_004192818.1\|1512741_1513446_+	nitrate reductase molybdenum cofactor assembly chaperone	NA	NA	NA	NA
WP_004191967.1\|1513482_1514169_+	respiratory nitrate reductase subunit gamma	NA	NA	NA	NA
WP_004193869.1\|1514310_1516233_+	HAMP domain-containing protein	NA	NA	NA	NA
WP_004192421.1\|1516268_1516970_+	response regulator	NA	NA	NA	NA
WP_011204042.1\|1516941_1517118_-	hypothetical protein	NA	NA	NA	NA
WP_004193531.1\|1517116_1517893_+	exodeoxyribonuclease III	NA	NA	NA	NA
WP_004191998.1\|1518175_1519639_-\|transposase	IS1182-like element ISBma2 family transposase	A0A1X9I5T2	Streptococcus_phage	8.8e-80	38.6
WP_004192209.1\|1519772_1521308_-	nitrogen regulation protein NR(I)	NA	NA	NA	NA
WP_004532137.1\|1521345_1522440_-	nitrogen regulation protein NR(II)	NA	NA	NA	NA
WP_004192601.1\|1522654_1524070_-	type I glutamate--ammonia ligase	NA	NA	NA	NA
WP_004191860.1\|1524474_1524939_+	rhodanese-like domain-containing protein	NA	NA	NA	NA
WP_004192990.1\|1525191_1526010_-	competence/damage-inducible protein A	NA	NA	NA	NA
WP_004193555.1\|1526006_1526840_-	EI24 domain-containing protein	NA	NA	NA	NA
WP_009966722.1\|1526895_1527168_+	hypothetical protein	NA	NA	NA	NA
WP_004192998.1\|1527383_1528373_-	sterol desaturase family protein	NA	NA	NA	NA
WP_004192001.1\|1528389_1529382_-	beta-propeller fold lactonase family protein	A0A2H4JCI3	uncultured_Caudovirales_phage	3.5e-11	59.6
WP_004202033.1\|1529483_1533611_-	ATP-dependent RNA helicase HrpA	A0A1V0SBU4	Catovirus	4.3e-47	28.5
WP_004192168.1\|1533634_1535011_+	amino-acid N-acetyltransferase	NA	NA	NA	NA
WP_004193961.1\|1535063_1535339_+	oxidative damage protection protein	NA	NA	NA	NA
WP_076882745.1\|1535511_1536855_-	MHS family MFS transporter	NA	NA	NA	NA
WP_004199573.1\|1537051_1538578_-	CoA transferase	NA	NA	NA	NA
WP_004193195.1\|1538574_1540368_-	acyl-CoA dehydrogenase	NA	NA	NA	NA
WP_004193679.1\|1540476_1541379_+	LysR family transcriptional regulator	NA	NA	NA	NA
WP_004191998.1\|1541780_1543244_-\|transposase	IS1182-like element ISBma2 family transposase	A0A1X9I5T2	Streptococcus_phage	8.8e-80	38.6
WP_011832359.1\|1543360_1543927_-	hypothetical protein	NA	NA	NA	NA
WP_038802950.1\|1544070_1545191_-\|transposase	IS3 family transposase	S5WIU1	Leptospira_phage	3.6e-49	39.5
WP_004193468.1\|1545300_1545777_-	hypothetical protein	NA	NA	NA	NA
WP_009970291.1\|1545875_1546217_+	hypothetical protein	NA	NA	NA	NA
WP_004200110.1\|1546233_1546458_+	hypothetical protein	NA	NA	NA	NA
WP_004193210.1\|1546714_1547851_+	D-alanyl-D-alanine carboxypeptidase	NA	NA	NA	NA
WP_004522511.1\|1547948_1548488_-\|protease	serine protease inhibitor ecotin	NA	NA	NA	NA

DBSCAN-SWA_6

2060178 : 2115776

Leptospira_phage(18.75%)

tRNA,transposase,protease

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_038802950.1\|2060178_2061299_-\|transposase	IS3 family transposase	S5WIU1	Leptospira_phage	3.6e-49	39.5
WP_004550771.1\|2061581_2062103_-	hypothetical protein	NA	NA	NA	NA
WP_004191998.1\|2062368_2063832_+\|transposase	IS1182-like element ISBma2 family transposase	A0A1X9I5T2	Streptococcus_phage	8.8e-80	38.6
WP_004186453.1\|2063954_2064935_-	4-hydroxy-3-methylbut-2-enyl diphosphate reductase	NA	NA	NA	NA
WP_004186190.1\|2064937_2065393_-	peptidylprolyl isomerase	NA	NA	NA	NA
WP_004185928.1\|2065531_2066368_+	JAB domain-containing protein	NA	NA	NA	NA
WP_004186391.1\|2066661_2066895_+	50S ribosomal protein L28	NA	NA	NA	NA
WP_004185395.1\|2066912_2067080_+	50S ribosomal protein L33	NA	NA	NA	NA
WP_004554550.1\|2067202_2068849_+	L-aspartate oxidase	NA	NA	NA	NA
WP_004197485.1\|2068820_2069039_-	hypothetical protein	NA	NA	NA	NA
WP_004185611.1\|2069040_2069925_-	carboxylating nicotinate-nucleotide diphosphorylase	NA	NA	NA	NA
WP_004185886.1\|2069921_2071058_-	quinolinate synthase NadA	NA	NA	NA	NA
WP_004186237.1\|2071226_2072423_-	aminotransferase	NA	NA	NA	NA
WP_004186398.1\|2072619_2073972_-	mechanosensitive ion channel	NA	NA	NA	NA
WP_004186079.1\|2073983_2075246_-	RsmB/NOP family class I SAM-dependent RNA methyltransferase	NA	NA	NA	NA
WP_004185746.1\|2075242_2075905_-	phosphoribosylglycinamide formyltransferase	E3SNR5	Prochlorococcus_phage	1.6e-25	40.0
WP_004535897.1\|2076029_2077022_+	bifunctional riboflavin kinase/FAD synthetase	NA	NA	NA	NA
WP_004185348.1\|2077133_2079971_+\|tRNA	isoleucine--tRNA ligase	A0A1V0SJ93	Klosneuvirus	1.6e-80	26.0
WP_004186086.1\|2079970_2080471_+	lipoprotein signal peptidase	NA	NA	NA	NA
WP_004186216.1\|2080532_2081744_+	bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase CoaBC	Q9HH70	Methanothermobacter_phage	3.0e-41	31.9
WP_004186718.1\|2081807_2082254_+	dUTP diphosphatase	Q2NP83	Xanthomonas_phage	7.9e-48	64.4
WP_004185819.1\|2082342_2083125_-	membrane protein	NA	NA	NA	NA
WP_011832233.1\|2083289_2084033_-	hypothetical protein	NA	NA	NA	NA
WP_096325437.1\|2084293_2085413_+\|transposase	IS3 family transposase	S5WIU1	Leptospira_phage	3.6e-49	39.5
WP_071810810.1\|2085609_2085828_+	hypothetical protein	NA	NA	NA	NA
WP_004185496.1\|2086025_2086535_+	DUF192 domain-containing protein	A0A1B1IUW8	uncultured_Mediterranean_phage	5.5e-13	41.2
WP_004197486.1\|2086835_2088950_+	elongation factor G	E4ZFJ7	Streptococcus_phage	5.8e-56	26.7
WP_009936593.1\|2089231_2089438_+	hypothetical protein	NA	NA	NA	NA
WP_038796688.1\|2090122_2091601_+	hypothetical protein	NA	NA	NA	NA
WP_004186341.1\|2092145_2092991_-	aldo/keto reductase	A0A2H4PQR8	Staphylococcus_phage	3.4e-23	29.9
WP_004185897.1\|2093159_2093906_+	GntR family transcriptional regulator	NA	NA	NA	NA
WP_004197492.1\|2094621_2095983_+	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_004522619.1\|2095955_2096291_-	DUF2917 domain-containing protein	NA	NA	NA	NA
WP_004185818.1\|2096587_2098027_+	DHA2 family efflux MFS transporter permease subunit	NA	NA	NA	NA
WP_004200476.1\|2098709_2099984_+	EAL domain-containing protein	NA	NA	NA	NA
WP_004185918.1\|2100115_2100721_-	class I SAM-dependent methyltransferase	NA	NA	NA	NA
WP_011204108.1\|2101020_2101182_-	hypothetical protein	NA	NA	NA	NA
WP_004186428.1\|2101260_2102283_-	2-dehydropantoate 2-reductase	NA	NA	NA	NA
WP_004185585.1\|2102298_2102826_-	DUF962 domain-containing protein	NA	NA	NA	NA
WP_004185910.1\|2102910_2103666_+	Crp/Fnr family transcriptional regulator	NA	NA	NA	NA
WP_004186611.1\|2103899_2105105_+	chromate efflux transporter	NA	NA	NA	NA
WP_096325437.1\|2105193_2106314_-\|transposase	IS3 family transposase	S5WIU1	Leptospira_phage	3.6e-49	39.5
WP_004185841.1\|2107376_2107955_-	superoxide dismutase	Q56AR7	Bacillus_thuringiensis_phage	1.1e-44	44.7
WP_004197496.1\|2108151_2109534_-	exodeoxyribonuclease VII large subunit	A0A1B3AYB4	Gordonia_phage	6.1e-30	27.5
WP_004200482.1\|2109528_2109759_+	hypothetical protein	NA	NA	NA	NA
WP_004555967.1\|2109991_2111020_+	tetraacyldisaccharide 4'-kinase	NA	NA	NA	NA
WP_004196455.1\|2111000_2111207_+	Trm112 family protein	NA	NA	NA	NA
WP_004185994.1\|2111380_2112172_+	3-deoxy-manno-octulosonate cytidylyltransferase	NA	NA	NA	NA
WP_009929233.1\|2112192_2112390_+	hypothetical protein	NA	NA	NA	NA
WP_004185840.1\|2112380_2113043_+	adenylate kinase	NA	NA	NA	NA
WP_004191998.1\|2113158_2114622_+\|transposase	IS1182-like element ISBma2 family transposase	A0A1X9I5T2	Streptococcus_phage	8.8e-80	38.6
WP_004196460.1\|2114725_2114929_-	cold-shock protein	A0A2H4N7Y6	Lake_Baikal_phage	6.8e-23	81.8
WP_004194131.1\|2115461_2115776_+\|protease	ATP-dependent Clp protease adapter ClpS	A0A218MMY6	uncultured_virus	4.4e-13	44.6

DBSCAN-SWA_7

2165922 : 2175159

unidentified_phage(16.67%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_004194112.1\|2165922_2167470_+	polynucleotide adenylyltransferase PcnB	H7BUW3	unidentified_phage	4.3e-24	31.2
WP_004194373.1\|2167506_2168034_+	2-amino-4-hydroxy-6- hydroxymethyldihydropteridine diphosphokinase	NA	NA	NA	NA
WP_004194274.1\|2168030_2168714_+	deoxynucleoside kinase	A0A249XZR7	Enterococcus_phage	2.6e-05	26.0
WP_004194137.1\|2168778_2169594_+	3-methyl-2-oxobutanoate hydroxymethyltransferase	A0A0N7HVJ8	Ostreococcus_lucimarinus_virus	8.8e-37	33.3
WP_004194350.1\|2169769_2171776_-	bifunctional anthranilate synthase component I family protein/class IV aminotransferase	S4VT78	Pandoravirus	9.7e-53	35.0
WP_004194374.1\|2171809_2172940_-	molecular chaperone DnaJ	A0A1V0SBY2	Catovirus	2.9e-22	27.6
WP_004194034.1\|2173206_2175159_-	molecular chaperone DnaK	A0A1V0SH73	Hokovirus	2.7e-148	49.2

DBSCAN-SWA_8

2260115 : 2301285

Leptospira_phage(21.43%)

tRNA,transposase,portal

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_004189649.1\|2260115_2261900_-\|tRNA	arginine--tRNA ligase	NA	NA	NA	NA
WP_004189319.1\|2262102_2262426_+	DUF1840 domain-containing protein	NA	NA	NA	NA
WP_004191998.1\|2262531_2263995_-\|transposase	IS1182-like element ISBma2 family transposase	A0A1X9I5T2	Streptococcus_phage	8.8e-80	38.6
WP_096325434.1\|2264082_2265203_-\|transposase	IS3 family transposase	S5WIU1	Leptospira_phage	3.6e-49	39.5
WP_004197759.1\|2265580_2266135_+	YaeQ family protein	NA	NA	NA	NA
WP_004197761.1\|2266314_2266731_-	lactoylglutathione lyase	NA	NA	NA	NA
WP_004190110.1\|2267132_2268227_+	bifunctional DNA-binding transcriptional regulator/O6-methylguanine-DNA methyltransferase Ada	A0A0G2Y1B6	Acanthamoeba_polyphaga_mimivirus	3.8e-19	37.4
WP_004200726.1\|2268223_2269165_+	DNA-3-methyladenine glycosylase 2 family protein	NA	NA	NA	NA
WP_004204797.1\|2269336_2270938_+	glutamate--cysteine ligase	NA	NA	NA	NA
WP_011832311.1\|2270956_2272405_-	RNA polymerase sigma factor RpoD/SigA	A0A2I7SAT0	Vibrio_phage	4.9e-30	33.5
WP_011203779.1\|2272401_2272653_-	hypothetical protein	NA	NA	NA	NA
WP_004189689.1\|2272668_2273217_-	hypothetical protein	NA	NA	NA	NA
WP_004189874.1\|2273809_2274379_-	periplasmic heavy metal sensor	NA	NA	NA	NA
WP_004189434.1\|2274481_2275450_-	LysR family transcriptional regulator	NA	NA	NA	NA
WP_011832313.1\|2275592_2276687_+	polyamine ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_004190014.1\|2276715_2277828_+	histone deacetylase	A0A2K9KZC4	Tupanvirus	3.2e-37	30.8
WP_004189258.1\|2277838_2278714_+	N-carbamoylputrescine amidase	A7IVZ1	Paramecium_bursaria_Chlorella_virus	9.6e-74	47.3
WP_011203781.1\|2278920_2279085_+	hypothetical protein	NA	NA	NA	NA
WP_011203781.1\|2279892_2280057_+	hypothetical protein	NA	NA	NA	NA
WP_004188948.1\|2280709_2281723_+\|portal	phage portal protein	A4JWQ2	Burkholderia_virus	1.3e-194	99.4
WP_004188977.1\|2281795_2282080_-	hypothetical protein	NA	NA	NA	NA
WP_004200731.1\|2282076_2282559_-	DUF2778 domain-containing protein	NA	NA	NA	NA
WP_096325434.1\|2282609_2283730_-\|transposase	IS3 family transposase	S5WIU1	Leptospira_phage	3.6e-49	39.5
WP_004197759.1\|2284107_2284662_+	YaeQ family protein	NA	NA	NA	NA
WP_004197761.1\|2284841_2285258_-	lactoylglutathione lyase	NA	NA	NA	NA
WP_004190110.1\|2285659_2286754_+	bifunctional DNA-binding transcriptional regulator/O6-methylguanine-DNA methyltransferase Ada	A0A0G2Y1B6	Acanthamoeba_polyphaga_mimivirus	3.8e-19	37.4
WP_004200726.1\|2286750_2287692_+	DNA-3-methyladenine glycosylase 2 family protein	NA	NA	NA	NA
WP_004204797.1\|2287863_2289465_+	glutamate--cysteine ligase	NA	NA	NA	NA
WP_011832311.1\|2289483_2290932_-	RNA polymerase sigma factor RpoD/SigA	A0A2I7SAT0	Vibrio_phage	4.9e-30	33.5
WP_011203779.1\|2290928_2291180_-	hypothetical protein	NA	NA	NA	NA
WP_004189689.1\|2291195_2291744_-	hypothetical protein	NA	NA	NA	NA
WP_004189874.1\|2292336_2292906_-	periplasmic heavy metal sensor	NA	NA	NA	NA
WP_004189434.1\|2293008_2293977_-	LysR family transcriptional regulator	NA	NA	NA	NA
WP_011832313.1\|2294119_2295214_+	polyamine ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_004190014.1\|2295242_2296355_+	histone deacetylase	A0A2K9KZC4	Tupanvirus	3.2e-37	30.8
WP_004189258.1\|2296365_2297241_+	N-carbamoylputrescine amidase	A7IVZ1	Paramecium_bursaria_Chlorella_virus	9.6e-74	47.3
WP_011203781.1\|2297447_2297612_+	hypothetical protein	NA	NA	NA	NA
WP_004188948.1\|2298264_2299278_+\|portal	phage portal protein	A4JWQ2	Burkholderia_virus	1.3e-194	99.4
WP_004188977.1\|2299350_2299635_-	hypothetical protein	NA	NA	NA	NA
WP_004200731.1\|2299631_2300114_-	DUF2778 domain-containing protein	NA	NA	NA	NA
WP_038802950.1\|2300164_2301285_-\|transposase	IS3 family transposase	S5WIU1	Leptospira_phage	3.6e-49	39.5

DBSCAN-SWA_9

2695456 : 2700382

Burkholderia_virus(33.33%)

terminase,transposase,portal,protease

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_096325434.1\|2695456_2696577_-\|transposase	IS3 family transposase	S5WIU1	Leptospira_phage	3.6e-49	39.5
WP_076835668.1\|2697357_2697681_+	type II toxin-antitoxin system RelE/ParE family toxin	A4JWV2	Burkholderia_virus	4.1e-54	97.2
WP_004202809.1\|2697683_2698040_+	putative addiction module antidote protein	A4JWV1	Burkholderia_virus	3.9e-42	100.0
WP_004199886.1\|2698083_2699139_-\|portal	phage portal protein	K4NZV0	Burkholderia_phage	5.7e-206	99.4
WP_004199888.1\|2699135_2699633_-\|terminase	terminase	K4NXI4	Burkholderia_phage	2.6e-55	100.0
WP_004539219.1\|2699854_2700382_-\|protease	ClpXP protease specificity-enhancing factor	A0A1S5R3H3	Pseudomonas_phage	2.0e-21	51.0

DBSCAN-SWA_10

3097848 : 3148923

Leptospira_phage(33.33%)

transposase,plate,holin

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_004198632.1\|3097848_3098202_+\|holin	phage holin family protein	NA	NA	NA	NA
WP_004198631.1\|3098219_3099050_+	methylenetetrahydrofolate reductase [NAD(P)H]	NA	NA	NA	NA
WP_004198630.1\|3099233_3100724_-	6-aminohexanoate-cyclic-dimer hydrolase	NA	NA	NA	NA
WP_004198629.1\|3100820_3101513_-	carboxymethylenebutenolidase	NA	NA	NA	NA
WP_004198628.1\|3101708_3101825_-	hypothetical protein	NA	NA	NA	NA
WP_096325434.1\|3102888_3104008_+\|transposase	IS3 family transposase	S5WIU1	Leptospira_phage	3.6e-49	39.5
WP_011205263.1\|3104117_3104630_+\|plate	type VI secretion system baseplate subunit TssE	NA	NA	NA	NA
WP_004200010.1\|3106504_3107605_+\|plate	type VI secretion system baseplate subunit TssG	NA	NA	NA	NA
WP_004202807.1\|3107638_3110308_+	type VI secretion system ATPase TssH	A0A223W0B1	Agrobacterium_phage	3.8e-89	32.0
WP_004200005.1\|3110397_3111519_+	type VI secretion system protein TssA	NA	NA	NA	NA
WP_004185296.1\|3111717_3112650_-	OmpA family protein	NA	NA	NA	NA
WP_004200003.1\|3112654_3113644_-	type VI secretion system-associated protein TagF	NA	NA	NA	NA
WP_004200001.1\|3113640_3117534_-	type VI secretion system membrane subunit TssM	NA	NA	NA	NA
WP_011204174.1\|3117509_3117788_-	hypothetical protein	NA	NA	NA	NA
WP_004527832.1\|3117805_3118771_-	M15 family metallopeptidase	NA	NA	NA	NA
WP_004199997.1\|3118782_3119739_+	hypothetical protein	NA	NA	NA	NA
WP_004199995.1\|3119949_3121398_-	TolC family protein	NA	NA	NA	NA
WP_004199993.1\|3121394_3123656_-	peptidase domain-containing ABC transporter	W8CYL7	Bacillus_phage	4.2e-36	27.7
WP_004199991.1\|3123670_3124939_-	HlyD family efflux transporter periplasmic adaptor subunit	NA	NA	NA	NA
WP_012729786.1\|3124964_3125321_+	hypothetical protein	NA	NA	NA	NA
WP_004204906.1\|3125554_3125785_-	hypothetical protein	NA	NA	NA	NA
WP_011205259.1\|3125887_3126157_-	hypothetical protein	NA	NA	NA	NA
WP_071893038.1\|3126199_3126598_-	hypothetical protein	NA	NA	NA	NA
WP_004204896.1\|3127179_3129345_-	peptidase	A0A0P0IY26	Acinetobacter_phage	1.9e-46	27.1
WP_009922408.1\|3129383_3129479_+	hypothetical protein	NA	NA	NA	NA
WP_011204170.1\|3129910_3130453_+	hypothetical protein	NA	NA	NA	NA
WP_004202806.1\|3130412_3130892_-	hypothetical protein	NA	NA	NA	NA
WP_004185303.1\|3130890_3132009_+	acyltransferase	NA	NA	NA	NA
WP_011204169.1\|3132153_3132369_+	hypothetical protein	NA	NA	NA	NA
WP_004198067.1\|3132365_3133502_+	class I SAM-dependent methyltransferase	NA	NA	NA	NA
WP_004198065.1\|3133629_3134526_+	SAM-dependent methyltransferase	NA	NA	NA	NA
WP_004198063.1\|3134610_3135234_-	DUF1415 domain-containing protein	NA	NA	NA	NA
WP_011204168.1\|3135230_3135581_-	hypothetical protein	NA	NA	NA	NA
WP_004198062.1\|3135571_3136216_-	TetR/AcrR family transcriptional regulator	NA	NA	NA	NA
WP_004198061.1\|3136374_3137658_+	MFS transporter	NA	NA	NA	NA
WP_004198060.1\|3137617_3138193_-	hypothetical protein	NA	NA	NA	NA
WP_004202805.1\|3138154_3138760_+	nitroreductase family protein	NA	NA	NA	NA
WP_004198058.1\|3139357_3140620_+	Hsp70 family protein	NA	NA	NA	NA
WP_004191998.1\|3140829_3142293_-\|transposase	IS1182-like element ISBma2 family transposase	A0A1X9I5T2	Streptococcus_phage	8.8e-80	38.6
WP_004196861.1\|3142416_3143304_-	16S rRNA (cytidine(1402)-2'-O)-methyltransferase	NA	NA	NA	NA
WP_011204167.1\|3143302_3143785_+	YraN family protein	NA	NA	NA	NA
WP_004196857.1\|3143907_3144486_+	SIS domain-containing protein	NA	NA	NA	NA
WP_011857937.1\|3144504_3145275_+	BON domain-containing protein	NA	NA	NA	NA
WP_004551036.1\|3145301_3145637_+	c-type cytochrome	NA	NA	NA	NA
WP_004196848.1\|3145950_3147357_-	amino acid permease	NA	NA	NA	NA
WP_004196846.1\|3147379_3147577_+	hypothetical protein	NA	NA	NA	NA
WP_011204166.1\|3147560_3147692_+	hypothetical protein	NA	NA	NA	NA
WP_096325434.1\|3147802_3148923_-\|transposase	IS3 family transposase	S5WIU1	Leptospira_phage	3.6e-49	39.5

DBSCAN-SWA_11

3384411 : 3422752

Burkholderia_phage(22.22%)

transposase,protease

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_004203414.1\|3384411_3384948_+\|protease	ATP-dependent protease subunit HslV	NA	NA	NA	NA
WP_004198316.1\|3384957_3386301_+\|protease	ATP-dependent protease ATPase subunit HslU	A0A191ZC11	Erwinia_phage	3.7e-40	28.8
WP_004198315.1\|3386727_3387270_-	response regulator transcription factor	NA	NA	NA	NA
WP_004198314.1\|3387289_3388570_-	HAMP domain-containing histidine kinase	NA	NA	NA	NA
WP_004198312.1\|3388587_3388839_-	cysteine-rich CWC family protein	NA	NA	NA	NA
WP_004200214.1\|3389163_3390063_+	acetylglutamate kinase	NA	NA	NA	NA
WP_004198307.1\|3390059_3390863_+	pyrimidine 5'-nucleotidase	NA	NA	NA	NA
WP_004198306.1\|3390829_3391519_+	nucleoid occlusion factor SlmA	NA	NA	NA	NA
WP_004198305.1\|3391871_3393017_+	homoserine O-acetyltransferase	NA	NA	NA	NA
WP_004198304.1\|3393013_3393628_+	methionine biosynthesis protein MetW	NA	NA	NA	NA
WP_004198303.1\|3393639_3394953_+	AmpG family muropeptide MFS transporter	NA	NA	NA	NA
WP_073699166.1\|3395026_3395986_+	M48 family metallopeptidase	NA	NA	NA	NA
WP_004198301.1\|3396359_3397304_-	AraC family transcriptional regulator	NA	NA	NA	NA
WP_004187628.1\|3397449_3398670_+\|transposase	ISL3-like element ISBma1 family transposase	A9YX10	Burkholderia_phage	7.8e-239	99.5
WP_004198300.1\|3398826_3399891_+	NAD(P)-dependent alcohol dehydrogenase	A0A2K9L339	Tupanvirus	1.3e-80	46.1
WP_004191998.1\|3400117_3401581_-\|transposase	IS1182-like element ISBma2 family transposase	A0A1X9I5T2	Streptococcus_phage	8.8e-80	38.6
WP_004196764.1\|3401754_3402081_-	iron donor protein CyaY	NA	NA	NA	NA
WP_004545632.1\|3402117_3402402_+	lipoprotein	NA	NA	NA	NA
WP_004196768.1\|3402412_3403684_+	diaminopimelate decarboxylase	NA	NA	NA	NA
WP_004196773.1\|3403942_3404656_-	protein-methionine-sulfoxide reductase heme-binding subunit MsrQ	NA	NA	NA	NA
WP_004196774.1\|3404677_3405673_-	protein-methionine-sulfoxide reductase catalytic subunit MsrP	NA	NA	NA	NA
WP_038802950.1\|3405772_3406893_-\|transposase	IS3 family transposase	S5WIU1	Leptospira_phage	3.6e-49	39.5
WP_004198356.1\|3407831_3409022_+	elongation factor Tu	A0A1V0SLW6	Klosneuvirus	1.5e-13	27.9
WP_004185179.1\|3409199_3409580_+	preprotein translocase subunit SecE	NA	NA	NA	NA
WP_004198369.1\|3409581_3410139_+	transcription termination/antitermination protein NusG	NA	NA	NA	NA
WP_004198368.1\|3410284_3410716_+	50S ribosomal protein L11	NA	NA	NA	NA
WP_004185135.1\|3410716_3411415_+	50S ribosomal protein L1	NA	NA	NA	NA
WP_004199864.1\|3411712_3412210_+	50S ribosomal protein L10	NA	NA	NA	NA
WP_004198366.1\|3412273_3412648_+	50S ribosomal protein L7/L12	NA	NA	NA	NA
WP_004198365.1\|3413011_3417118_+	DNA-directed RNA polymerase subunit beta	E3T4Z4	Cafeteria_roenbergensis_virus	4.6e-25	21.4
WP_011857943.1\|3417139_3421378_+	DNA-directed RNA polymerase subunit beta'	A0A2I7QNZ7	Vibrio_phage	2.3e-72	27.9
WP_004202761.1\|3421531_3422752_+\|transposase	ISL3 family transposase	A9YX10	Burkholderia_phage	1.3e-238	99.3

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. NC_009079

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection

2. NC_009080

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection