CRISPRimmunity

Please click to download your results

Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NC_011143	Phenylobacterium zucineum HLK1 plasmid unnamed, complete sequence	0 crisprs	NA	0	0	1	0
NC_011144	Phenylobacterium zucineum HLK1, complete sequence	5 crisprs	csa3,WYL,RT,DinG,cas3	3	5	2	1

Results visualization

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

324415 : 374836

Shigella_phage(22.22%)

transposase

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_012520261.1\|324415_325951_-\|transposase	IS21 family transposase	K4I413	Acidithiobacillus_phage	3.8e-126	46.4
WP_049758529.1\|326011_326407_-	DUF302 domain-containing protein	NA	NA	NA	NA
WP_041374521.1\|326416_326824_-	hypothetical protein	NA	NA	NA	NA
WP_012520517.1\|327058_328399_-	phenylacetate--CoA ligase family protein	NA	NA	NA	NA
WP_083771057.1\|328829_329177_+	DUF1857 family protein	NA	NA	NA	NA
WP_012520520.1\|329333_331253_-	PAS domain-containing protein	Q8QKV7	Ectocarpus_siliculosus_virus	3.8e-06	26.0
WP_041374522.1\|331435_331639_-	hypothetical protein	NA	NA	NA	NA
WP_049758531.1\|331740_332469_-	Crp/Fnr family transcriptional regulator	NA	NA	NA	NA
WP_041374523.1\|332609_332822_-	hypothetical protein	NA	NA	NA	NA
WP_148217053.1\|333010_333313_+	hypothetical protein	NA	NA	NA	NA
WP_086004007.1\|334212_335384_-\|transposase	IS3 family transposase	U5P429	Shigella_phage	1.3e-57	43.6
WP_012520523.1\|335654_336278_+	glutathione transferase GstA	NA	NA	NA	NA
WP_012520524.1\|336331_337120_+	exodeoxyribonuclease III	A0A0N9QXX6	Chrysochromulina_ericina_virus	4.4e-17	25.1
WP_049758533.1\|337132_337492_-	response regulator transcription factor	NA	NA	NA	NA
WP_012520526.1\|337644_338595_+	RNA polymerase sigma factor RpoH	M4SMP8	Cyanophage	1.1e-11	26.7
WP_012520527.1\|338672_339569_+	mechanosensitive ion channel family protein	NA	NA	NA	NA
WP_049758534.1\|339791_340907_+	hypothetical protein	NA	NA	NA	NA
WP_041374525.1\|340957_341743_-	hypothetical protein	NA	NA	NA	NA
WP_041374526.1\|341862_342171_-	hypothetical protein	NA	NA	NA	NA
WP_012520530.1\|342312_342765_+	hypothetical protein	NA	NA	NA	NA
WP_012520531.1\|342817_343843_-	relaxase/mobilization nuclease domain-containing protein	NA	NA	NA	NA
WP_187149128.1\|343939_344305_+	hypothetical protein	NA	NA	NA	NA
WP_012520532.1\|344590_344947_-	hypothetical protein	NA	NA	NA	NA
WP_012520534.1\|346282_346936_+	MBL fold metallo-hydrolase	NA	NA	NA	NA
WP_012520535.1\|347037_348594_-	SH3 domain-containing protein	NA	NA	NA	NA
WP_041374528.1\|348719_348983_+	hypothetical protein	NA	NA	NA	NA
WP_012520536.1\|349044_349440_-	response regulator	NA	NA	NA	NA
WP_012520537.1\|349956_350982_-\|transposase	IS110 family transposase	NA	NA	NA	NA
WP_012520538.1\|351276_351987_+	hypothetical protein	NA	NA	NA	NA
WP_012520539.1\|351983_352580_+	RES family NAD+ phosphorylase	NA	NA	NA	NA
WP_041374529.1\|352576_352855_-	hypothetical protein	NA	NA	NA	NA
WP_012520541.1\|352906_353341_-	hypothetical protein	NA	NA	NA	NA
WP_012520542.1\|353344_353602_-	type II toxin-antitoxin system Phd/YefM family antitoxin	NA	NA	NA	NA
WP_012520543.1\|353690_354095_-	single-stranded DNA-binding protein	A0A1X9SGJ7	Bradyrhizobium_phage	1.6e-23	50.0
WP_012520544.1\|354647_355070_-	hypothetical protein	NA	NA	NA	NA
WP_012520545.1\|355172_355643_+	putative interphotoreceptor retinol- binding protein	NA	NA	NA	NA
WP_041374530.1\|356301_357051_+	hypothetical protein	NA	NA	NA	NA
WP_012520547.1\|357254_358661_-	amidase	NA	NA	NA	NA
WP_049758537.1\|359013_360519_+	NAD(P)/FAD-dependent oxidoreductase	NA	NA	NA	NA
WP_012520549.1\|360555_361467_+	SDR family oxidoreductase	NA	NA	NA	NA
WP_041374531.1\|361566_362208_+	cyclic nucleotide-binding domain-containing protein	NA	NA	NA	NA
WP_012520551.1\|362306_363146_+	enoyl-CoA hydratase/isomerase family protein	NA	NA	NA	NA
WP_012520552.1\|363155_363986_-	enoyl-CoA hydratase/isomerase family protein	NA	NA	NA	NA
WP_041374533.1\|364413_364722_-	hypothetical protein	NA	NA	NA	NA
WP_041374534.1\|365924_366158_-	hypothetical protein	NA	NA	NA	NA
WP_012520555.1\|366491_367220_-	hypothetical protein	NA	NA	NA	NA
WP_187149129.1\|367219_367660_-	hypothetical protein	NA	NA	NA	NA
WP_086004007.1\|367740_368911_+\|transposase	IS3 family transposase	U5P429	Shigella_phage	1.3e-57	43.6
WP_049758539.1\|368937_369903_-	hypothetical protein	NA	NA	NA	NA
WP_086004002.1\|369996_371162_-\|transposase	IS3 family transposase	S5WIU1	Leptospira_phage	7.6e-50	46.4
WP_041374535.1\|371221_371467_-	ArdC family protein	NA	NA	NA	NA
WP_012520556.1\|371712_373842_-	strawberry notch C-terminal domain-containing protein	V5LQJ6	Emiliania_huxleyi_virus	7.2e-06	30.3
WP_012520421.1\|373807_374836_+\|transposase	IS110 family transposase	NA	NA	NA	NA

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

2. NC_011144

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Crispr_ID: NC_011144_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_011144_1

1160253-1160386

Orphan

Consensus_repeat	Method
GGCCCCCTCCACCGCTGTCGCGGTCCCCCTCCCCCGA	CRISPRCasFinder

1 spacers

The CRISPR arrays of NC_011144_1

>merge|NC_011144|1|1160253-1160386|CRISPRCasFinder
GGCCCCCTCCACCGCTGTCGCGGTCCCCCTCCCCCGACGGGGGAGGAGGGGGGCGGGCGTCGACGGGGGCCTGCAACCTAGCTCGGAGCGTGGGGCGGGCCCCCTCCACCGCTATCGCGGTCCCCCTCCCCCGA

>NC_011144|1|1|1160253-1160386|CRISPRCasFinder
GGCCCCCTCCACCGCTGTCGCGGTCCCCCTCCCCCGA	CGGGGGAGGAGGGGGGCGGGCGTCGACGGGGGCCTGCAACCTAGCTCGGAGCGTGGGGCG
GGCCCCCTCCACCGCTATCGCGGTCCCCCTCCCCCGA

Protein	Signature genes	Signature genes Name	Protein_function
NC_011144.1\|WP_041373258.1\|1151662_1151878_+\|hypothetical-protein	unknown	unknown	unknown
NC_011144.1\|WP_183281129.1\|1154818_1154974_-\|hypothetical-protein	unknown	unknown	unknown
NC_011144.1\|WP_041373267.1\|1169293_1170337_+\|alpha/beta-hydrolase-fold-domain-containing-protein	unknown	unknown	gnl\|CDD\|369561
NC_011144.1\|WP_041373264.1\|1166365_1166788_-\|response-regulator	unknown	unknown	gnl\|CDD\|381099
NC_011144.1\|WP_012521592.1\|1150932_1151325_-\|endonuclease-domain-containing-protein	unknown	unknown	gnl\|CDD\|238509
NC_011144.1\|WP_041373265.1\|1167071_1167380_+\|hypothetical-protein	unknown	unknown	unknown
NC_011144.1\|WP_012521596.1\|1157583_1159398_+\|response-regulator	unknown	unknown	gnl\|CDD\|237425
NC_011144.1\|WP_012521599.1\|1164331_1164946_+\|GDYXXLXY-domain-containing-protein	unknown	unknown	gnl\|CDD\|379571
NC_011144.1\|WP_012521594.1\|1155089_1157051_+\|TonB-dependent-receptor	unknown	unknown	gnl\|CDD\|238657
NC_011144.1\|WP_183281137.1\|1168661_1168811_-\|hypothetical-protein	unknown	unknown	unknown
NC_011144.1\|WP_187149113.1\|1165049_1166348_+\|C4-dicarboxylate-transporter-DctA	unknown	unknown	gnl\|CDD\|234968
NC_011144.1\|WP_012521595.1\|1157050_1157587_+\|YfiR-family-protein	unknown	unknown	gnl\|CDD\|379335
NC_011144.1\|WP_041373263.1\|1160470_1162963_-\|TonB-dependent-receptor	unknown	unknown	gnl\|CDD\|238657
NC_011144.1\|WP_148216801.1\|1159799_1160153_+\|hypothetical-protein	unknown	unknown	unknown
NC_011144.1\|WP_187149101.1\|1151942_1154441_+\|MASE1-domain-containing-protein	unknown	unknown	gnl\|CDD\|274362
NC_011144.1\|WP_012521602.1\|1167376_1168483_-\|helix-turn-helix-transcriptional-regulator	unknown	unknown	gnl\|CDD\|225360
NC_011144.1\|WP_041373260.1\|1154536_1154812_+\|hypothetical-protein	unknown	unknown	unknown
NC_011144.1\|WP_012521603.1\|1168881_1169259_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|197715
NC_011144.1\|WP_012521598.1\|1163273_1164335_+\|DUF2157-domain-containing-protein	unknown	unknown	gnl\|CDD\|378311
NC_011144.1\|WP_148216800.1\|1159422_1159803_+\|hypothetical-protein	unknown	unknown	unknown

Protein	Function_ID	Function_description	E-value
NC_011144.1\|WP_041373264.1\|1166365_1166788_-\|response-regulator	gnl\|CDD\|381099	cd17546, REC_hyHK_CKI1_RcsC-like, phosphoacceptor receiver (REC) domain of hybrid sensor histidine kinases/response regulators similar to Arabidopsis thaliana CKI1 and Escherichia coli RcsC. This family is composed of hybrid sensor histidine kinases/response regulators that are sensor histidine kinases (HKs) fused with a REC domain, similar to the sensor histidine kinase CKI1 from Arabidopsis thaliana, which is involved in multi-step phosphorelay (MSP) signaling that mediates responses to a variety of important stimuli in plants. MSP involves a signal being transferred from HKs via histidine phosphotransfer proteins (AHP1-AHP5) to nuclear response regulators. The CKI1 REC domain specifically interacts with the downstream signaling protein AHP2, AHP3 and AHP5. The plant MSP system has evolved from the prokaryotic two-component system (TCS), which allows organisms to sense and respond to changes in environmental conditions. This family also includes bacterial hybrid sensor HKs such as Escherichia coli RcsC, which is a component of the Rcs signalling pathway that controls a variety of physiological functions like capsule synthesis, cell division, and motility. REC domains function as phosphorylation-mediated switches within response regulators, but some also transfer phosphoryl groups in multistep phosphorelays.	9.61054e-41
NC_011144.1\|WP_012521592.1\|1150932_1151325_-\|endonuclease-domain-containing-protein	gnl\|CDD\|238509	cd01038, Endonuclease_DUF559, Domain of unknown function, appears to be related to a diverse group of endonucleases.	1.39286e-32
NC_011144.1\|WP_012521596.1\|1157583_1159398_+\|response-regulator	gnl\|CDD\|237425	PRK13557, PRK13557, histidine kinase; Provisional.	7.25639e-108
NC_011144.1\|WP_012521599.1\|1164331_1164946_+\|GDYXXLXY-domain-containing-protein	gnl\|CDD\|379571	pfam14345, GDYXXLXY, GDYXXLXY protein. This family of proteins is functionally uncharacterized. This family of proteins is found in bacteria, archaea and eukaryotes. Proteins in this family are typically between 171 and 199 amino acids in length. It contains a conserved GDYXXLXY motif.	9.99427e-20
NC_011144.1\|WP_012521594.1\|1155089_1157051_+\|TonB-dependent-receptor	gnl\|CDD\|238657	cd01347, ligand_gated_channel, TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel. Energy (proton-motive force) and TonB-dependent conformational alteration of channel (parts of plug, and loops 7 and 8) allow passage of ligand. FepA residues 12-18 form the TonB box, which mediates the interaction with the TonB-containing inner membrane complex. TonB preferentially interacts with ligand-bound receptors. Transport thru the channel may resemble passage thru an air lock. In this model, ligand binding leads to closure of the extracellular end of pore, then a TonB-mediated signal facillitates opening of the interior side of pore, deforming the N-terminal plug and allowing passage of the ligand to the periplasm. Such a mechanism would prevent the free diffusion of small molecules thru the pore.	2.43427e-38
NC_011144.1\|WP_187149113.1\|1165049_1166348_+\|C4-dicarboxylate-transporter-DctA	gnl\|CDD\|234968	PRK01663, PRK01663, C4-dicarboxylate transporter DctA; Reviewed.	0
NC_011144.1\|WP_012521595.1\|1157050_1157587_+\|YfiR-family-protein	gnl\|CDD\|379335	pfam13689, DUF4154, Domain of unknown function (DUF4154). This family of proteins is found in bacteria. Proteins in this family are typically between 172 and 207 amino acids in length. Many members are annotated as valyl-tRNA synthetase but this could not be confirmed.	9.78851e-44
NC_011144.1\|WP_041373263.1\|1160470_1162963_-\|TonB-dependent-receptor	gnl\|CDD\|238657	cd01347, ligand_gated_channel, TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel. Energy (proton-motive force) and TonB-dependent conformational alteration of channel (parts of plug, and loops 7 and 8) allow passage of ligand. FepA residues 12-18 form the TonB box, which mediates the interaction with the TonB-containing inner membrane complex. TonB preferentially interacts with ligand-bound receptors. Transport thru the channel may resemble passage thru an air lock. In this model, ligand binding leads to closure of the extracellular end of pore, then a TonB-mediated signal facillitates opening of the interior side of pore, deforming the N-terminal plug and allowing passage of the ligand to the periplasm. Such a mechanism would prevent the free diffusion of small molecules thru the pore.	2.68575e-39
NC_011144.1\|WP_041373267.1\|1169293_1170337_+\|alpha/beta-hydrolase-fold-domain-containing-protein	gnl\|CDD\|369561	pfam07859, Abhydrolase_3, alpha/beta hydrolase fold. This catalytic domain is found in a very wide range of enzymes.	4.05682e-44
NC_011144.1\|WP_187149101.1\|1151942_1154441_+\|MASE1-domain-containing-protein	gnl\|CDD\|274362	TIGR02956, sensor_protein_TorS, TMAO reductase sytem sensor TorS. This protein, TorS, is part of a regulatory system for the torCAD operon that encodes the pterin molybdenum cofactor-containing enzyme trimethylamine-N-oxide (TMAO) reductase (TorA), a cognate chaperone (TorD), and a penta-haem cytochrome (TorC). TorS works together with the inducer-binding protein TorT and the response regulator TorR. TorS contains histidine kinase ATPase (pfam02518), HAMP (pfam00672), phosphoacceptor (pfam00512), and phosphotransfer (pfam01627) domains and a response regulator receiver domain (pfam00072). [Signal transduction, Two-component systems].	3.0777e-86
NC_011144.1\|WP_012521602.1\|1167376_1168483_-\|helix-turn-helix-transcriptional-regulator	gnl\|CDD\|225360	COG2771, CsgD, DNA-binding HTH domain-containing proteins [Transcription].	3.90792e-07
NC_011144.1\|WP_012521603.1\|1168881_1169259_-\|hypothetical-protein	gnl\|CDD\|197715	smart00421, HTH_LUXR, helix_turn_helix, Lux Regulon. lux regulon (activates the bioluminescence operon.	2.03034e-06
NC_011144.1\|WP_012521598.1\|1163273_1164335_+\|DUF2157-domain-containing-protein	gnl\|CDD\|378311	pfam09925, DUF2157, Predicted membrane protein (DUF2157). This domain, found in various hypothetical prokaryotic proteins, has no known function.	1.62601e-20

>NC_011144.1|WP_148216801.1|1159799_1160153_+|hypothetical-protein
MTLRRGLKILLAAGAGLGLAGCETLGAGRVKPAAPPPVIAVSPPPVVQVEPPPAQARPRPERSCVPRSLGPPPRYPDTDAALRNAAGAADRYQLLAAGRLLRQKRLAELERAIAACR
>NC_011144.1|WP_148216800.1|1159422_1159803_+|hypothetical-protein
MIHSLRHALTSRMAGPVATALAMVLAATLGLAWADWTADRAVLERRIAELTQQADRSQSLWKAQLAACHAAAGANRLTEAAYESSGGTPEGDPKDAARRLLSQQPEGIDVCARMESADQAVLSTLK
>NC_011144.1|WP_012521596.1|1157583_1159398_+|response-regulator
MKLAWPDLTDRRQVGLAWMAALALTAFALLLGGFNELNYRRSTAADAVAQAQLLAGSVSGALAFQDRETLSEQLGALRLNPAVVSAAAYDARGRPLVAYAKEGSAAPPQTAPPPGARRLGGAVLVTREVTESGVRLGAVYLSTRPQPLAGVLMRHGGLAVLTLVAYALLAVLTRAGLQLQRRADELATANERLTVEMAEREKAEEALRQSQKMEALGQLTGGIAHDFNNLLQVVQGAFELISRRADDPAKVKAYAAHGLHATERGASLAKQLLAFSRAQKLELKPFVVADLIRDMRQLLVRTLGPNVTLDFRFDDDKIAVVSDRTQLELAVLNLAINARDAMPDGGTLTIVTRPRPIPAGHPTLPPDTYLELCVSDTGKGMPAEVAERAFDPFFTTKGVGKGTGLGLSQVYGVARQAGGEAVIQTAPGEGTTVSLLLRRSDAAPAERPEAARAEAGHAAPPNARVMVVDDDDEVRRLVCDSLDLLGYEVEAAGDGPTALAELDRVQPDLLLLDFAMPGMNGAEVATAARARRGGLPIVFASGYAETDAVRQAVGRGAVILRKPFEIDDLARVVREALSQAPRPQTGHGPEKDTGGSLTLDGGAR
>NC_011144.1|WP_012521595.1|1157050_1157587_+|YfiR-family-protein
MGAPARTRLAAAALAAAALAPAAAGAQPLETQVKAAFLAKFAAFASWPPGVLETAPALRICVVGRDPFAGALERASRSQTVSGRPLAVVRMAEVDRGSGCHVMYASGSDRQSAAQALAAVRGQPVLTVTDAARGGARGMIHFVVFEERVRFYVDLAEAQRSGLGLSSKLLSVALTVKR
>NC_011144.1|WP_012521594.1|1155089_1157051_+|TonB-dependent-receptor
MRRRGEGVRTRLAAATAVAALAGALAGAGLTAGTAQAEEAAAPPGPAQALGELSIEELSQVNVTSVSKRPEPLGHAAASIYLITNEALLRSGAMSLPEALRLAPNVEVLRIDALDYSISSRGFAGFESSNKQLVLVDGRSVYTPLFSGVDWDQHHLVMEDIERIEVISGPGGTLWGANAVNGVINVVSKSAFDTDGLLAAANLGTLDSDVRLRAGRPLGDIAAGRVYVTAFRRGDLETADGADANDGWDGWQAGFRVDVAGDRDTFTLQGDVQDADIPESLGFASGYARGGNLVARWTRRTAGGTQLELQGYYDVMEREARQAHDEQRVWDAALQVSRPIGTRHQLVAGGGYRVTKDEFRTLLEPQLLATPRRTTEIGNLFVEDEIALTPELLLAVGVKLETNSYTKAEWMPSARLGWRVSERQFLWASVSRAVRNPSRIERDFTIEGLVRPGVMGSEKLIAYEGGWRGRLTPRATASITLFYHDYDDIRTNELTPPGTLPIVVGNGIEGETWGVEAWADVQVTDRWRLSVGGVRLEKQFRIKDGVIDLSGFEAAGADPAWWLKANSHIDLTDRLSLDVGVRAFDAIPRLAPADYVGADGYVEAQARLAFKVREDLELSLTGLNLLHARHAEASEARRNEIPRSVHVGLRWMR
>NC_011144.1|WP_183281129.1|1154818_1154974_-|hypothetical-protein
MGKWIGILIAAIVALAVVGFLVDAARAIAGFLLVVCLIVLAVQVFWKRSRG
>NC_011144.1|WP_041373260.1|1154536_1154812_+|hypothetical-protein
MNSLAPAAQIAAIAAAVSGPFLAGLAVVMWSKARAARRQQRLAELEGDLRGLYGKVAEDAVPERLAMVVDALEEGQALKPAGKAADSKAPA
>NC_011144.1|WP_187149101.1|1151942_1154441_+|MASE1-domain-containing-protein
MTAFPPLAPAGAALLWRIALLVAVVAGLSYVGMVAPKEAGKVAPIWLANAPVLACLLRAPVRNWWIWVAAGLAGSLAGEIAAGGRLEPSVALSLCSSLEVVLCATVAGKLIGGQMDVTRAWHLAAMALSACLSAVISATLASSYLGLMGEGRFLDHLMLWSVSNALGLTLLTPCLLVLVEWRGWLAERPMSRAGAASLTGLAGLAVAVFGQDSWPLTFLIPPAILVACLTLEMFGAAVAVMLTCSIAVGFTLKDHGPLAMTSGGWTARLMVLQLFLLVDALLAFQVAALLRNRRLMREELEAARQEAEARAADAEEAKSQYRLLAERVTDVMSRSTVTGQITYLSPSVVKLSGFSPEDLVGQQMLEGVHPEDQAAFLHAHMDMLRGRRAPGTPIRYRVACKTGGWVWIEGNPSLVRDERGRPVEFVDVSRNVTERVELEARLAAAVAEAERAATVKSDFLANMSHEIRTPLTSILGFASFLDELKLPEPAGGYAAKVTTASRTLLAIVNDVLDFSKLEAGRLEMKPRPTDPAECARDVLDLFGPQAQAKGLELVLEPAAPAVAMIDADRLRQVLMNLVGNAVKFTQSGSVRLSCAYDPAERRLTCKVADTGPGIGAAAMEKLFQRFSQVDGSTTRAHGGTGLGLAISKGLVEAMGGRIGVESAPGRGSTFWFEAPAEPAAAAPAEADEAPDVQVMAGVRVLAADDNPQNLEIVRSILTPLGVDLTEAQSGAEAVEAARLAPFDVILMDLRMPGVDGWAAANAIREGHGPNRDAPILAFSADVAPDRREAMGVFQDLVSKPIEPPALLRAILRWTLAEPAAADGEESSGRAAG
>NC_011144.1|WP_041373258.1|1151662_1151878_+|hypothetical-protein
MREPDPQRSAALRLLIGAALAAALGSSAGAALRPAPAERGGPAAPQQIYLDGVALSAAEQSGGGWPARARS
>NC_011144.1|WP_012521592.1|1150932_1151325_-|endonuclease-domain-containing-protein
MYAPKATVGRARALRRRMTPPEVRLWRVLRGKALDGLRFRRQHPIGSYVLDFYCEAAALCVEVDGQRHWLGRAQERDAERDAWLAARGIRTLRLSASLVLEDMDAALRAIAAEARRRPPPSSPIGGGGPR
>NC_011144.1|WP_041373263.1|1160470_1162963_-|TonB-dependent-receptor
MLSCALMALGGGAAQAQTVIEELVVTAEKREQSLQDVPVAVSAFTDERREMVGINSVQDLTNFTPGLAYSTNNDRINMRGIGRFTNNRSSEGGVAMYNDGVYTSSVTAFARSTLFIDRTEALRGPQGTLYGRNSIGGALNIISKRPTDDFYAEVRAGMGNYDTWMTEAAISGPLVGNIRGRLAGSYNSQGEGYFTNLNPNGKSEGGRGDQWQVEGQLDGELGDGKLEWWLKVDSAEWHNLGRGPGGRTTITYGLRDVTSPLQAALTPNSAALGLPLGLPGNQCQFCFDTDDGNYISLENNGYAFNATLHLDSFDVKYIAGYTYYDYRLQTDLDATSRQAPFQLPVSTQPYYPRRNNQYQEEVWWFSNEINIASTYDSPLQWLIGAYQFREGSNYTLSDARHPDDARFENPTLFSLNPATQLIPAAPNPERRYAYGSSENRSESYAVFGQADWQFTDELKFTAGLRYTYDRKRSFESARLFCLYTATCPISRVTGRPVDVTAVAAPGTSTDPAVYLPAFTDPTTGLRHRGLKYDWSGITGTLGVDWQPDPDTLAYAKYTRGYKAGGFNSGTTTLTPNVTTQEETIDAYEVGLKKTFGGTFQANASAFLYDYQDIQVPITGRDPVTDLNVTRFFNMPKARIVGFELETIWQPIDNLQILANYSYLNAELKEACCFQDPEDPRGLQPGVVLAGNTAAALASPTAGLNQDLDGAKLPSSTPHRVTFNVNYTWEFDVGELSASLTHVWKDKTYYSIFNRYYNEGKAWHQTDARLLWNDIDDRYTLIAYVKNIFEQEGVAGADGSRINTGPNTGFINRTISYVPPRTYGVELQYRF
>NC_011144.1|WP_012521598.1|1163273_1164335_+|DUF2157-domain-containing-protein
MASYRRRLERDLDGWIGRGLVPAASREAILADLGEARRLDAATTLAVLGALLAAAAAVAFVAANWSAIPRIVRFGLILGVFLASAGGAAWASARERTVTTHALLAVAAIVFGAAIGLTGQIFDLTGDAQAALRGAGLAAALLALAGRSPWPAAVALLFIGLGDMSGSGWFEGAPRWPGWLVWAAPLGAATALAWRSTPLAHAAGIASIAAVLSLTQIAPRHPEALFLAAAAVLAALALVARGLRDGREGVASPLYGWWTWGALIWFGAAGLGEAFRGVPHAVAWLALAAAVLVLGRHDRHAAVTGAGVVGLFAAGASLLFNLGVGLMTSAAVFAVCAVAALVVALLLKRGRAA
>NC_011144.1|WP_012521599.1|1164331_1164946_+|GDYXXLXY-domain-containing-protein
MRFGTPARIVTAAGLLALALIGLVVREGVARAQGREVRLAIEAYDPRSLLSGHYLQFQIQDRPAGDSACPPGAEGDPRSRIRGWIALVPAGGRHRAAGFADSRAGAERLGPVAVRGRLTCLPRGRPGPEGAQMEPDMTAVLDLGVDRFHAEQDQAERMEAALVRGAEGTPDGETPLAVVSVGRDGKARLKAVVIGGRRTDLDWF
>NC_011144.1|WP_187149113.1|1165049_1166348_+|C4-dicarboxylate-transporter-DctA
MRRTPIWNQLYVQVLVAIAVGGAIGHFWPETGEALKPLGDAFIKLVKMIIAPVIFLTVTTGIAGMRDIGKVGGVAAKAFGYFIVVSSFALVVGLVVANVVQPGAGMNVDPATLDAGAVQDYAAKSHEMTITGFLMDIIPATVAGAFVSGNILQVLFFSIPFGLALAMIGERGEPALAVLNAVAEAFFRLVAIFMRAAPIGALGAFAFTVGRYGLESIVNLAALVGTFYATSLIFVLVVLGAIARLHGFSILRLIRYLKEELLLVLGTSSSEAALPSLLEKMERAGAPKTVVGLVVPTGYSFNLDGTNIYMTLAALFIAQAVGIDLPLGEQLLLLAVAMLSSKGAAGVTGAGFITLAATLSVVPSVPVAGMALILGVDRFMSECRALTNFVGNAVATLVVSRWEGQLDRQALEDALSGAPQPIAAPPVEADAD
>NC_011144.1|WP_041373264.1|1166365_1166788_-|response-regulator
MSDAQGPARRLRVLHVDDDAMNLRVVQEILEAFGHSAVMAASGDEALEHLSREAFDVVLMDIHMPGMTGVEAVRRLRASAGPGRDTPVIAVTADVLSRRPQEYVALGFNDFVAKPILVSGLMASVTRAAAARATPLSRAS
>NC_011144.1|WP_041373265.1|1167071_1167380_+|hypothetical-protein
MQQAANAASITAGWLVGVMIEVEGEPRPLRHYYAVGLADRDQAQWRAVDRAIAAGRVATSPVGGLEPVQAVNPLTLARMRTLGLAAGEVRELGWRHPRRWMS
>NC_011144.1|WP_012521602.1|1167376_1168483_-|helix-turn-helix-transcriptional-regulator
MIANDEHWTAVADLFAAAALDGSWPVALEGLADACGAERGELIGVGADRAVPFNWMTRMDPSGLDEFVGMGGGDPARNPRVRMGLRAPLLASWHDVRCATEDELRRNFDYADYCRRWDIPYGSQSTLMRDDGMLIGLAVLRGERRGVPQAEDRRAFESLVGQVRAAVRTQITLEGQGPALLAGALESAGVAAFVCDGAGRARAHTPAAEGALRRGLLRLRGGRLDAARDEDGRALEAAVLRAARGTAPRPLLQTLVLRAPGDPAAFEVVDVAALPLRPHGLGFEPRALVIVRGARRDDQLPELLRQVFGLSPAEADIAVRLARGESREAVAARRGVSLETVRSQVKALFAKLDIGREGELAARLDRLR
>NC_011144.1|WP_183281137.1|1168661_1168811_-|hypothetical-protein
MPRLFTATDRPPARGGGASRVVVRWRRLAETLALAASLAGLAAVLLGAL
>NC_011144.1|WP_012521603.1|1168881_1169259_-|hypothetical-protein
MSDDDAFDQRLLKSATAYSKLYPSIGARLKAAYESGHPLAREAARAIRAAAERADGARAQHLRDVHGLSPQETRIVLHLVDGGAVSSAALALGVAESTIRSHLKSTFAKTGVRRQADLRSLLPGG
>NC_011144.1|WP_041373267.1|1169293_1170337_+|alpha/beta-hydrolase-fold-domain-containing-protein
MSVSVGVGQPFAGLGGVQIMDRPGEAALKSLARRAANKTMQWLVTRSMRQAVRAHAAGPEAFLAYVERQRRIHERFDAPILPMMEAEAIRVAGPGVLSSPPAPSEWFAPKAAKPRGHVFYVHGGSFVAERSPRITQLVARFAATAEAQVFAPSYRLAPEHPCPAAVEDIVEAWAWFRRTYPDEPVVALAESAGAAVLLSALQQANARGLGLPGGVVLLSPWVDLSLQSWSVTAASLMGSSPYTMESLALVARFYLNGLSATDPVASPLFGSFDGFPPMLIHASQGDILYDDAVRLADKVRDAGGDLTVRLWSEETHVWERMNTPKAKQSILLAADFIRRRLDAAALN

You can click texts colored in the table to view more detailed information

Click the colored protein region to show detailed information

Crispr_ID: NC_011144_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_011144_2

1418678-1418926

Orphan

Consensus_repeat	Method
NATCGCCGGCTCGGGCGA	CRT

4 spacers

The CRISPR arrays of NC_011144_2

>merge|NC_011144|2|1418678-1418926|CRT
CATCGCCGGATCGGGCAACGTGGCGGTCCGCTCGATCTCAGGCCCGCTGGAGGTGGCGATCGCCGGCTCGGGCGACGTCACCGTGGCCGCCGGCCGCGCCACGGCCATGACGGTCTCGGTCGCCGGCTCGGGCGATGTGGATTTCCGGGGGCAGGCCGAGAGCGTGAAGGCCAAGATCGCCGGCTCGGGCGACGTGCGCGTCCGCGAGGTGAAGGGCGAGGTCTCCAAGACCATCATGGGCTCGGGCGC

>NC_011144|2|1|1418678-1418926|CRT
CATCGCCGGATCGGGCAA	CGTGGCGGTCCGCTCGATCTCAGGCCCGCTGGAGGTGGC
GATCGCCGGCTCGGGCGA	CGTCACCGTGGCCGCCGGCCGCGCCACGGCCATGACGGTCTC
GGTCGCCGGCTCGGGCGA	TGTGGATTTCCGGGGGCAGGCCGAGAGCGTGAAGGCCAA
GATCGCCGGCTCGGGCGA	CGTGCGCGTCCGCGAGGTGAAGGGCGAGGTCTCCAAGAC
CATCATGGGCTCGGGCGC

Protein	Signature genes	Signature genes Name	Protein_function
NC_011144.1\|WP_012521795.1\|1423611_1424040_+\|50S-ribosomal-protein-L16	unknown	unknown	gnl\|CDD\|236411
NC_011144.1\|WP_012521779.1\|1409057_1411022_+\|S9-family-peptidase	unknown	unknown	gnl\|CDD\|224423
NC_011144.1\|WP_012521790.1\|1421029_1421332_+\|50S-ribosomal-protein-L23	unknown	unknown	gnl\|CDD\|235586
NC_011144.1\|WP_012521789.1\|1420391_1421030_+\|50S-ribosomal-protein-L4	unknown	unknown	gnl\|CDD\|235404
NC_011144.1\|WP_012521781.1\|1411572_1412676_+\|ferritin-like-domain-containing-protein	unknown	unknown	gnl\|CDD\|153097
NC_011144.1\|WP_012521769.1\|1416763_1417954_+\|elongation-factor-Tu	unknown	unknown	gnl\|CDD\|234596
NC_011144.1\|WP_012521784.1\|1414059_1414533_+\|30S-ribosomal-protein-S7	unknown	unknown	gnl\|CDD\|235398
NC_011144.1\|WP_012521796.1\|1424039_1424234_+\|50S-ribosomal-protein-L29	unknown	unknown	gnl\|CDD\|178971
NC_011144.1\|WP_012521780.1\|1411099_1411426_+\|zf-TFIIB-domain-containing-protein	unknown	unknown	gnl\|CDD\|226331
NC_011144.1\|WP_012521794.1\|1422836_1423598_+\|30S-ribosomal-protein-S3	unknown	unknown	gnl\|CDD\|234722
NC_011144.1\|WP_012521785.1\|1414635_1416714_+\|elongation-factor-G	unknown	unknown	gnl\|CDD\|234569
NC_011144.1\|WP_012521783.1\|1413676_1414048_+\|30S-ribosomal-protein-S12	unknown	unknown	gnl\|CDD\|235355
NC_011144.1\|WP_012521788.1\|1419606_1420392_+\|50S-ribosomal-protein-L3	unknown	unknown	gnl\|CDD\|234564
NC_011144.1\|WP_012521791.1\|1421336_1422173_+\|50S-ribosomal-protein-L2	unknown	unknown	gnl\|CDD\|236488
NC_011144.1\|WP_012521778.1\|1404726_1408920_+\|DNA-directed-RNA-polymerase-subunit-beta'	unknown	unknown	gnl\|CDD\|234794
NC_011144.1\|WP_012521792.1\|1422176_1422455_+\|30S-ribosomal-protein-S19	unknown	unknown	gnl\|CDD\|178985
NC_011144.1\|WP_012521787.1\|1419284_1419593_+\|30S-ribosomal-protein-S10	unknown	unknown	gnl\|CDD\|179076
NC_011144.1\|WP_012521793.1\|1422456_1422837_+\|50S-ribosomal-protein-L22	unknown	unknown	gnl\|CDD\|234793
NC_011144.1\|WP_041373301.1\|1412693_1413347_-\|hypothetical-protein	unknown	unknown	unknown
NC_011144.1\|WP_012521777.1\|1400554_1404625_+\|DNA-directed-RNA-polymerase-subunit-beta	unknown	unknown	gnl\|CDD\|234749

Protein	Function_ID	Function_description	E-value
NC_011144.1\|WP_012521795.1\|1423611_1424040_+\|50S-ribosomal-protein-L16	gnl\|CDD\|236411	PRK09203, rplP, 50S ribosomal protein L16; Reviewed.	3.72336e-93
NC_011144.1\|WP_012521779.1\|1409057_1411022_+\|S9-family-peptidase	gnl\|CDD\|224423	COG1506, DAP2, Dipeptidyl aminopeptidases/acylaminoacyl-peptidases [Amino acid transport and metabolism].	2.93977e-78
NC_011144.1\|WP_012521790.1\|1421029_1421332_+\|50S-ribosomal-protein-L23	gnl\|CDD\|235586	PRK05738, rplW, 50S ribosomal protein L23; Reviewed.	5.85754e-46
NC_011144.1\|WP_012521789.1\|1420391_1421030_+\|50S-ribosomal-protein-L4	gnl\|CDD\|235404	PRK05319, rplD, 50S ribosomal protein L4; Provisional.	5.3801e-104
NC_011144.1\|WP_012521785.1\|1414635_1416714_+\|elongation-factor-G	gnl\|CDD\|234569	PRK00007, PRK00007, elongation factor G; Reviewed.	0
NC_011144.1\|WP_012521781.1\|1411572_1412676_+\|ferritin-like-domain-containing-protein	gnl\|CDD\|153097	cd00657, Ferritin_like, Ferritin-like superfamily of diiron-containing four-helix-bundle proteins. Ferritin-like, diiron-carboxylate proteins participate in a range of functions including iron regulation, mono-oxygenation, and reactive radical production. These proteins are characterized by the fact that they catalyze dioxygen-dependent oxidation-hydroxylation reactions within diiron centers; one exception is manganese catalase, which catalyzes peroxide-dependent oxidation-reduction within a dimanganese center. Diiron-carboxylate proteins are further characterized by the presence of duplicate metal ligands, glutamates and histidines (ExxH) and two additional glutamates within a four-helix bundle. Outside of these conserved residues there is little obvious homology. Members include bacterioferritin, ferritin, rubrerythrin, aromatic and alkene monooxygenase hydroxylases (AAMH), ribonucleotide reductase R2 (RNRR2), acyl-ACP-desaturases (Acyl_ACP_Desat), manganese (Mn) catalases, demethoxyubiquinone hydroxylases (DMQH), DNA protecting proteins (DPS), and ubiquinol oxidases (AOX), and the aerobic cyclase system, Fe-containing subunit (ACSF).	5.95087e-20
NC_011144.1\|WP_012521769.1\|1416763_1417954_+\|elongation-factor-Tu	gnl\|CDD\|234596	PRK00049, PRK00049, elongation factor Tu; Reviewed.	0
NC_011144.1\|WP_012521796.1\|1424039_1424234_+\|50S-ribosomal-protein-L29	gnl\|CDD\|178971	PRK00306, PRK00306, 50S ribosomal protein L29; Reviewed.	1.02011e-23
NC_011144.1\|WP_012521780.1\|1411099_1411426_+\|zf-TFIIB-domain-containing-protein	gnl\|CDD\|226331	COG3809, COG3809, Uncharacterized protein conserved in bacteria [Function unknown].	1.68021e-20
NC_011144.1\|WP_012521794.1\|1422836_1423598_+\|30S-ribosomal-protein-S3	gnl\|CDD\|234722	PRK00310, rpsC, 30S ribosomal protein S3; Reviewed.	6.7777e-155
NC_011144.1\|WP_012521788.1\|1419606_1420392_+\|50S-ribosomal-protein-L3	gnl\|CDD\|234564	PRK00001, rplC, 50S ribosomal protein L3; Validated.	2.39161e-120
NC_011144.1\|WP_012521783.1\|1413676_1414048_+\|30S-ribosomal-protein-S12	gnl\|CDD\|235355	PRK05163, rpsL, 30S ribosomal protein S12; Validated.	1.28969e-84
NC_011144.1\|WP_012521791.1\|1421336_1422173_+\|50S-ribosomal-protein-L2	gnl\|CDD\|236488	PRK09374, rplB, 50S ribosomal protein L2; Validated.	0
NC_011144.1\|WP_012521778.1\|1404726_1408920_+\|DNA-directed-RNA-polymerase-subunit-beta'	gnl\|CDD\|234794	PRK00566, PRK00566, DNA-directed RNA polymerase subunit beta'; Provisional.	0
NC_011144.1\|WP_012521792.1\|1422176_1422455_+\|30S-ribosomal-protein-S19	gnl\|CDD\|178985	PRK00357, rpsS, 30S ribosomal protein S19; Reviewed.	1.47173e-61
NC_011144.1\|WP_012521787.1\|1419284_1419593_+\|30S-ribosomal-protein-S10	gnl\|CDD\|179076	PRK00596, rpsJ, 30S ribosomal protein S10; Reviewed.	8.3849e-69
NC_011144.1\|WP_012521793.1\|1422456_1422837_+\|50S-ribosomal-protein-L22	gnl\|CDD\|234793	PRK00565, rplV, 50S ribosomal protein L22; Reviewed.	1.68772e-53
NC_011144.1\|WP_012521784.1\|1414059_1414533_+\|30S-ribosomal-protein-S7	gnl\|CDD\|235398	PRK05302, PRK05302, 30S ribosomal protein S7; Validated.	7.09259e-104
NC_011144.1\|WP_012521777.1\|1400554_1404625_+\|DNA-directed-RNA-polymerase-subunit-beta	gnl\|CDD\|234749	PRK00405, rpoB, DNA-directed RNA polymerase subunit beta; Reviewed.	0

>NC_011144.1|WP_012521769.1|1416763_1417954_+|elongation-factor-Tu
MAKEKFERTKPHCNIGTIGHVDHGKTTLTAAITITLAKSGGATAKNYADIDAAPEEKARGITINTAHVEYETANRHYAHVDCPGHADYVKNMITGAAQMDGAILVVSAADGPMPQTREHILLARQVGVPALVVFMNKVDMVDDAELLDLVEMEVRELLSSYQFPGDDIPIVKGSALAAVEGRDPQIGEERILELMAAVDSYIPQPERPIDQPFLMPVEDVFSISGRGTVVTGRIEKGIVKVGDEVEIVGIREVQKTTCTGVEMFRKLLDQGQAGDNVGVLLRGTKREDVERGQVLCKPGSITPHTEFMAEAYILTKEEGGRHTPFFTNYRPQFYFRTTDVTGIIKLKEGVEMIMPGDNAELLVELITPIAMDQGLRFAIREGGRTVGAGVVAKIIK
>NC_011144.1|WP_012521785.1|1414635_1416714_+|elongation-factor-G
MPRTHKIEDYRNFGIMAHIDAGKTTTTERILFYTGKSHKIGEVHDGAATMDWMEQEQERGITITSAATTAFWNGKRLNIIDTPGHVDFTIEVERSLRVLDGAVTVLDGNAGVEPQTETVWRQADKYKVPRIVFVNKMDKLGADFDKSVESIRDRLGAKAVPIQLPIGAESALRGIIDLVRMKAVVWDTDALGAKFQDEEIPADLKEKAEAARNYMIENAVELDDEAMEAYLSGEEPSEEVIKKCIRKAVLTGAFYPILCGSAFKNKGVQPLLDAVVDYLPSPVDIPPTKGIDFRTEEEVERRASDDEPLSVLAFKIMDDPFVGSLTFCRIYSGKLETGMGLMNSTRDKRERVGRMLLMHSNNREDIKEAYAGDIVALAGLKETRTGDTLCDPNKSPVILERMEFPEPVIEIAVEPKSKADQEKLGVALSKLAAEDPSFTVSTDHESGQTILKGMGELHLDIKIDILKRTYKVEANIGAPQVAYRESISKRTEIDYTHKKQTGGTGQFARVKLVFEPGEPGSGFVFESAIVGGAVPKEYVPGVQKGLESAKENGLLAGFPVIDFKATLVDGAFHDVDSSVLAFEIASRAAFKELREKGGPKLLEPIMAVEVVTPEEYLGSVIGDLNGRRGQIQGQDMRGNATVINAFVPLANMFGYVNNLRGMSQGRAQFTMLFSHYETVPQVVAEEVIKKYA
>NC_011144.1|WP_012521784.1|1414059_1414533_+|30S-ribosomal-protein-S7
MSRRRRADKREVLPDPKFGDLVVTKFMNYVMYEGKKAVAENIVYGAFDILEARRKDMGPLETFHAALDNVAPAIEVRSRRVGGATYQVPVEVRPERRRALAIRWLVNAARSRGENTMTEKLAGELLDASSNRGSAVKKREDTHKMAEANRAFSHYRW
>NC_011144.1|WP_012521783.1|1413676_1414048_+|30S-ribosomal-protein-S12
MPTVNQLIRKPRQTKPARNKVPALKGCPQRRGVCTRVYTTTPKKPNSALRKVAKVRLTTGIEAVCYIPGEGHNLQEHSVVLIRGGRVKDLPGVRYHILRGVLDTQGVKDRKQRRSLYGAKRPK
>NC_011144.1|WP_041373301.1|1412693_1413347_-|hypothetical-protein
MAISVVAHAAVLAALALHVPKLFVPPVRSGPPQPIIPVLLTPRTPPPEAGGPPRPIRLHRRQPRVPLDRLPVAPLVAPEAEPEPDAERDRRAPRVVTVDPVAQNARQTLRGLIGCANPSLLSREEREKCQEQLARGAREAEFPGLGLDADDASDLGRAAARREAGYRYKRSEESRPREPGSQVDWDVRRSPPAGASHMKGMGGSAHDASGAAGRSRN
>NC_011144.1|WP_012521781.1|1411572_1412676_+|ferritin-like-domain-containing-protein
MLQVQVVKGPPTEVQYFDEDDLAHRLTDHDVEVIREIFRTPLTGSYNWDYEAANARIRRLYELGKRFNWNSELDVDWGLQMPAPEGAPPEPEGFADHPKWKALSPEQKADFMRRTTAQTLSQFLHGEQGALMVASQLVSCAPTHDAKLYAASQTFDEARHVEVFHRYLMERCHMIYPINPNLKFLLDKVLTDERWDLKFIGMQILIEGLALAAFQTIHETTPDPLLKQVVGLVMRDEGRHVAFGVNYLEDWIRALPQAEIEERAQFAYEACVVMKNRLISTNVAEEFGFTREEALEINAKTQGGQAFRKFLFERMIPNLKRVGLLTEAIRPKFEELGVLEFENLQHDGLIDWAVLEAPLEMKDRVAA
>NC_011144.1|WP_012521780.1|1411099_1411426_+|zf-TFIIB-domain-containing-protein
MPLLLCPNDNTSMQNVNRGGVEIDICPTCRGVWLDRGELEKLLEGTRQEQTAQAEDRQRFDREVSDFHRDPDEWKKRHPYDREHGRYRYDDKYHYKKKKRFDIFDIFD
>NC_011144.1|WP_012521779.1|1409057_1411022_+|S9-family-peptidase
MRRVLAASAAAVVLAAAGQGAAAPPPASAFGRIPAVVQAAISPDGARVAVLGGHNDERVLSIATLDQPNLPQLRLGEVEAVGVRWAGDDYVLARLAYWEQVGARVAYRFERTVAVTPEGKAVSRLLDSGANNLLLSQPILGVTTEGGKPRVLMTGLMESGGASSGANTRLARKGVESDFVLALWSVDPATGRGSIVERGTYDTTSWEVDPSGAARVRLDIDELTHAFSIRGRAQGRSQYSQVWKGEDFASRRAYYGYSAPDDALIMAEGGRLVKRRLSDGAVEPFGPDVLPNNPELIWDEHRGAVVGVTAGAEKPVVAWTDPQVGAAHATLAKVFKDRRVDLRSWSKDRTRFVARVSGPGAPGVWYLFDTARKEVSPLGDEYPELAGAQLGATRWITYKARDGLEIPAYLTLPPAAATAGRKPPLVVLPHGGPRARDEYEFEYLVQFLASRGYAVLQPQFRGSWGFGDAFEEAGEGEWGGKMQTDLLDGVAALAAQGEVDAARACIVGASFGGYSALAGAALYPGAYRCAASIAGIADLGQLLLEQGRAYGRASAGLEELRVMIGAASPQKLADTSPAQHAAAVQAPVLLIHGDKDTVVAPAQSLRMAEALKAAGKPHELVILEGENHYLTRSSNRTRTLEALEAFLARHLPVS
>NC_011144.1|WP_012521778.1|1404726_1408920_+|DNA-directed-RNA-polymerase-subunit-beta'
MNQEVLNIFNPVQAAPTFDQIRIALASPEKIRSWSFGEIKKPETINYRTFKPERDGLFCARIFGPTKDYECLCGKYKRMKYKGIICEKCGVEVTLARVRRERMGHIELASPVAHIWFLKSLPSRIALMLDMALKDVERVLYFENYIVTEPGLTPLKLHQLLSEDDYLRFQEEFGDDSFTAEIGAEAVQGLLRGIDLEKEAENLREELKTTTSEMKLKKASKRLKLIENFIESGNKPEWMVLTVIPVIPPELRPLVPLDGGRFATSDLNDLYRRVINRNNRLKRLIELRAPDIIIRNEKRMLQEAVDALFDNGRRGRVITGANKRPLKSLADMLKGKQGRFRQNLLGKRVDYSGRSVIVVGPELKLHECGLPKKMALELFKPFIYARLDAKGLSGTVKQSKRMVEREQPAVWDILDEVIREHPVLLNRAPTLHRLGIQAFEPKLIEGKAIQLHPLVCAAFNADFDGDQMAVHVPLSLEAQLEARVLMMSTNNILSPANGRPIIVPSQDIVLGLYYLSLVKDGEPGEGKAFASLGEIEAALDAGVVTLHSKIRCRYTEMDADGNLVTKVIETSPGRMKIAALFPQHPAVGHRLLEKNLTKKEIGNLIDTVYRHCGQKATVIFADQIMGLGFREAAKAGISFGKDDIVIPARKAPIVEETRKLVEEYEQQYADGLITKGEKYNKVVDAWAKATDRVADEMMAEVSSAPVDENGRQAEINSIFMMSNSGARGSQAQMKQLGGMRGLMAKPSGEIIETPIISNFKEGLTVQEYFNSTHGARKGLADTALKTANSGYLTRRLVDVAQDCIITEEDCGTTRGITLRAVVEGGDVLVSLGQRILGRFAAEDVKDPGSNDVIVPADSYLDENMIELVESAGVQSVKVRSVLTCETKTGVCGACYGRDLARGTPVNIGEAVGVIAAQSIGEPGTQLTMRTFHIGGTAQVAEQSFYESANEGVAKISGGNTVTAPDGALISMSRNLMLTVQVDGKDRESYKVPYGARLRVKDGEGVKRGQRLAEWDPYTTPIITEVGGKVRFEDLVENVSFREEADEATGISNRVVVDWRASTKGSDLRPAMAVLGEDGSYKRLSNGGEARSLLPVGAILSVGDGDEVKPGEVLARMPTEGAKTRDITGGLPRVAELFEARRPKDCAVIAEMDGRVEFGRDYKNKRRIKITPEDGGEAVEFLIPKGKHIAVHDGDVIRKGEYLIDGNPDPHDILRIQGIEALADFLVNEIQEVYRLQGVPINDKHIETIVRQMLQKVEILEPGDTGLLKGDHLDKIEVDEENAKAEARGGRPALTQPVLLGITKASLQTRSFISAASFQETTRVLTEASVQGKIDTLEGLKENVIVGRLIPAGTGSYLRNLQRIAAKRDEALTQSREEAMEPLPAEIADAAVGEQVES
>NC_011144.1|WP_012521777.1|1400554_1404625_+|DNA-directed-RNA-polymerase-subunit-beta
MAQSFTGKKRIRKSFGRIPEAVQMPNLIEVQRSSYEQFLQREVRAGERRDEGIEAVFKSVFPIKDFNERAVLEYVSYEFEEPKYDVEECVQRDMTYAAPLKVKLRLIVFETDEETGARSVKDIKEQDVYMGDIPLMTEKGTFIVNGTQRVIVSQMHRSPGVFFDHDKGKTHASGKLLFAARVIPYRGSWLDFEFDAKDIVYVRIDRRRKLPATTFLMALGMDGEEILSTFYETVPYEKKGDGWATPYKPERWRGVKPEFPLIDADTGEEIAPAGQKISARNAKKFADNGLKTLLLAPEALTGRYLAKDLVNFETGEIYAEAGDELDPTLLAALEEQGFTTLDVLDIDEVTVGAYIRNTLRVDKNTAREDALFDIYRVMRPGEPPTVEAAEAMFKSLFFDSERYDLSSVGRVKMNMRLELDCPDDVRVIRKEDVIAVLLTLVGLRDGRGEIDDIDNLGNRRVRSVGELLENQYRVGLLRMERAIKERMSSVDIDTVMPHDLINAKPAAAAVREFFGSSQLSQFMDQTNPLSEITHKRRLSALGPGGLTRERAGFEVRDVHPTHYGRICPIETPEGPNIGLINSLATHAVVNKYGFIESPYRRIRDGKTTDEVVYMSAMEEAKHVIAQANIKLENGEIVEDLVPGRINGEPSLLPKADVDLMDVSPKQVVSVAASLIPFLENDDANRALMGSNMQKQAVPLIQSDAPLVGTGMESIVAVDSGAVVVARRTGVVEQIDGTRIVVRATEETDPSKPGVDIYRLQKFQRSNTSTCINQRPLVRVGDKINAGDVIADGPSTELGELALGRNALVAFMPWNGYNFEDSILISERIVRDDVFTSIHIEEFEVMARDTKLGPEEITRDIPNVGEEALRNLDEAGIVAIGAEVQPGDILVGKVTPKGESPMTPEEKLLRAIFGEKASDVRDTSLRLPPGVSGTIVEVRVFNRHGVDKDERALAIERAEIDRLGKDRDDEFAILNRNMQGRLRQLLVGKTAVSGPKGLGRGEITAEKLEEIAPGLWWQIALDDEKAMGELEALRKQFDDARKRLDRRFEDKVDKLQRGDELPPGVMKMVKVFVAVKRKLQPGDKMAGRHGNKGVISKILPIEDMPYLEDGTSVDIVLNPLGVPSRMNVGQIFETHLGWAAAGLGKQVQRLLEDWQHGGQKQALIEHLRDVYGPDEELPDTEEELVELARNLSKGIPFATPVFDGAHIDDIENLLEKAGLDRSGQSYLYDGQSGERFKRPVTVGYIYMLKLHHLVDDKIHARSIGPYSLVTQQPLGGKAQFGGQRFGEMEVWALEAYGAAYTLQEMLTVKSDDVAGRTKVYESIVRGDDTFEAGIPESFNVLVKEMRSLGLNVELENS
>NC_011144.1|WP_012521787.1|1419284_1419593_+|30S-ribosomal-protein-S10
MDRQNIRIRLKAFDHRVLDHSTREIVNTAKRTGATVRGPIPLPTRIEKFTVNRSPHIDKKSREQFEIRTHKRVLDIVDPTPQTVDALMKLDLSAGVDVEIKL
>NC_011144.1|WP_012521788.1|1419606_1420392_+|50S-ribosomal-protein-L3
MRTGVIAKKLGMARFFDEAGVHVPVTVLSLEGCQVVAHRTKDKDGYVALQLGAGSKKPKNTSKGLRGHFAKGQVEPKAKLVEFKVSEDNLIDVGAELTADHFVPGQKVDITGTTVGKGFAGAMKRWNFGGLRATHGVSVSHRSHGSTGQRQDPGRTFPGKKMAGHYGQETVTTLNLTVWRVDAERGLILVKGAVPGTEGTFVKIRDAVKAALPADAPKPGAFRGAGAPTPVEAAADEAAPAEEPAVTEAPAAEATEAGDQA
>NC_011144.1|WP_012521789.1|1420391_1421030_+|50S-ribosomal-protein-L4
MKLDVIKLDGGKGGSIELPDDIFGIEEIRADILQRCVTWQLAKRRAGTHKIQVRNEVSRTGKKMYKQKGTGGARHGSRRAAQFVGGAKAHGPVVRSHAFDLPKKVRALALRHALSSKAKDGSLIVLDSATLTEAKTAALRASFEKIGVTNALVIAGAQVDNNLKLAARNIPNVDVLPNAGLNVYDVLRRRTLVLTKDAVAAIQARFQPEEAA
>NC_011144.1|WP_012521790.1|1421029_1421332_+|50S-ribosomal-protein-L23
MAVEPTVRHYDTILSPIITEKATLLSEQNKVVFRVAGDATKDEIAAAVEALFKVNVTKVNTINVKGKTKRFRGIVGRRSDVKKAIVTLAEGQSIDITTGL
>NC_011144.1|WP_012521791.1|1421336_1422173_+|50S-ribosomal-protein-L2
MALKQFNPTSPGRRQLVLVDKSELHKGRPEKSLVEGLTKSGGRGGNGRISVRFRGGGAKRLYRVIDFKRRKFDVPATVERLEYDPNRSAFIALVKYEDGELAYILAPQRLKVGDQVIAAEKADVKPGNAMPLRGMPIGTIIHNVELKPLKGGQIARSAGTYAQLVGRDAGYAQIRLNSGELRMVQDGCMATVGAVSNPDHMNESLGKAGRSRHKGRRPHVRGVAMNPIDHPHGGGEGRTSGGRHPVTPWGKPTKGRKTRKNKATDKFIIRSRHARKAR
>NC_011144.1|WP_012521792.1|1422176_1422455_+|30S-ribosomal-protein-S19
MTRSVWKGPFVDGYLLKKAEAAQSSGRKDVIKTWSRRSTIMPQFVGLTFGVHNGHKHVPVLISEDMVGMKLGEFAPTRFFPGHAADKKAKRK
>NC_011144.1|WP_012521793.1|1422456_1422837_+|50S-ribosomal-protein-L22
MAKQAKARRLAGIEAMAKVRTLRTSPRKLNLVAQSIRGLKVQRALNELEFSHKRIARDVRKALYSAISNAENNHNLDIDNLVVAEAFVGKNLIMKRFHARARGRASRIEKPFSEITIVVREQGEAA
>NC_011144.1|WP_012521794.1|1422836_1423598_+|30S-ribosomal-protein-S3
MGQKINPVGLRLGINRTWDSRWFADGPEYGRLLHEDIKVRRALKKRLYQAGVSRIIIERPHKKCRITIYAARPGVIIGKKGADIEKLRKDVAAMTDGEVHLNIVEIRKPETDAQLIAENIAQQLERRVAFRRAMKRSMQSAMRLGAKGVRINVSGRLGGAEIARMEWYREGRVPLHTLRADVDYGFTEAKTTYGVIGVKVWVFKGEVLEHDPMALDKRLAGESGPAGEGGGRERGDRPDRGPRRERRGEPSNA
>NC_011144.1|WP_012521795.1|1423611_1424040_+|50S-ribosomal-protein-L16
MLSPKKTKYRKQFKGRIHGTAKGGFTLNFGSYGLKSMEPERITARQIEAARRAITRQMKRQGRVWIRVFPDVPVTGKPAEVRMGSGKGSVEYWAARVHPGRIMFEIDGVPDDVAREALRLGAAKLPVKTRIVTRIDAAVEHA
>NC_011144.1|WP_012521796.1|1424039_1424234_+|50S-ribosomal-protein-L29
MKIDEVRGMTPDQLNEQLVALKKEQFNLRFQKATGQIEKTHRVDEVRKDIARIKTVLRAKQAQA

You can click texts colored in the table to view more detailed information

Click the colored protein region to show detailed information

Crispr_ID: NC_011144_3

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_011144_3

2030730-2031103

Orphan

Consensus_repeat	Method
CCGCCGCCGAAGCCCCCGTCGCCGCC	CRISPRCasFinder

7 spacers

The CRISPR arrays of NC_011144_3

>merge|NC_011144|3|2030730-2031103|CRISPRCasFinder
GCCCCGCCCAGGCCCGCACCCCCGCCGCCCAGCCCGCCGGCCGAAGTGTTCGCCGAGCCCGCGCCGCCGCCGTAGCCACCCGCGCCGCCGAGATCGGTCCCAAGGGAACCGCCTCCCCCCCCGCCGCCACCGCCGCCGCCGAAGCCCCCGTCGCCGCCCGTGCCGCCGGGGACGCCGAAGCCCGCGCCGCCGCCCCCGCCGCCGAAGCCGCCGTCGCCGCCGTCGCCGGCCAGGCCGGAGCCGAAGGCCCCCCCGCCGCCGCCGCCGCCGAAGTCGCCGCCGTCGCCGCCGGGGAAGGTGCCGCCGGCCGTACCGCCCGCGCCGCCGTTGGCGCCGCCGCCGGATCCGCCGCCGCTGCCGCTCCAGTCCTGGCC

>NC_011144|3|2|2030730-2031103|CRISPRCasFinder
GCCCCGCCCAGGCCCGCACCCCCGCC	GCCCAGCCCGCCGGCCGAAGTGTTCGCCGAGCCCGCG
CCGCCGCCGTAGCCACCCGCGCCGCC	GAGATCGGTCCCAAGGGAA
CCGCCTCCCCCCCCGCCGCCACCGCC	GCCGCCGAAGCCCCCG
TCGCCGCCCGTGCCGCCGGGGACGCC	GAAGCCCGCGCCGCCG
CCCCCGCCGCCGAAGCCGCCGTCGCC	GCCGTCGCCGGCCAGG
CCGGAGCCGAAGGCCCCCCCGCCGCC	GCCGCCGCCGAAGTCGCCGCCGTCGCCGCCGGGGAAGGTG
CCGCCGGCCGTACCGCCCGCGCCGCC	GTTGGCGCCGCCGCCGGATCCG
CCGCCGCTGCCGCTCCAGTCCTGGCC

Protein	Signature genes	Signature genes Name	Protein_function
NC_011144.1\|WP_012522365.1\|2026637_2029040_-\|endopeptidase-La	unknown	unknown	gnl\|CDD\|223542
NC_011144.1\|WP_041373409.1\|2037228_2037441_+\|DUF2188-domain-containing-protein	unknown	unknown	gnl\|CDD\|378323
NC_011144.1\|WP_012522362.1\|2023893_2025297_-\|peptide-MFS-transporter	unknown	unknown	gnl\|CDD\|340904
NC_011144.1\|WP_012522361.1\|2022855_2023776_-\|aldo/keto-reductase	unknown	unknown	gnl\|CDD\|381321
NC_011144.1\|WP_012522369.1\|2033862_2035263_-\|trehalose-6-phosphate-synthase	unknown	unknown	gnl\|CDD\|274112
NC_011144.1\|WP_012522363.1\|2025323_2025896_-\|TMEM165/GDT1-family-protein	unknown	unknown	gnl\|CDD\|225030
NC_011144.1\|WP_012522370.1\|2035728_2036346_-\|ATP-dependent-Clp-protease-proteolytic-subunit	unknown	unknown	gnl\|CDD\|178955
NC_011144.1\|WP_012522357.1\|2018787_2019369_-\|NADH-quinone-oxidoreductase-subunit-B	unknown	unknown	gnl\|CDD\|235797
NC_011144.1\|WP_012522368.1\|2033239_2033866_+\|HAD-IB-family-hydrolase	unknown	unknown	gnl\|CDD\|273654
NC_011144.1\|WP_012522364.1\|2026187_2026463_-\|HU-family-DNA-binding-protein	unknown	unknown	gnl\|CDD\|259853
NC_011144.1\|WP_012522360.1\|2020840_2022766_-\|NAD(P)/FAD-dependent-oxidoreductase	unknown	unknown	gnl\|CDD\|224983
NC_011144.1\|WP_012522372.1\|2037437_2037794_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|369610
NC_011144.1\|WP_012522374.1\|2038536_2040411_+\|ABC-F-family-ATP-binding-cassette-domain-containing-protein	unknown	unknown	gnl\|CDD\|223562
NC_011144.1\|WP_041373408.1\|2035291_2035585_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|184052
NC_011144.1\|WP_012522371.1\|2036438_2037077_-\|DsbA-family-protein	unknown	unknown	gnl\|CDD\|239323
NC_011144.1\|WP_049758196.1\|2029349_2029799_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|380205
NC_011144.1\|WP_012522367.1\|2031742_2033005_-\|ATP-dependent-Clp-protease-ATP-binding-subunit-ClpX	unknown	unknown	gnl\|CDD\|235422
NC_011144.1\|WP_012522359.1\|2020034_2020817_-\|MliC-family-protein	unknown	unknown	gnl\|CDD\|378282
NC_011144.1\|WP_012522373.1\|2037858_2038278_-\|nucleoside-diphosphate-kinase	unknown	unknown	gnl\|CDD\|179085
NC_011144.1\|WP_012522358.1\|2019338_2019716_-\|NADH-quinone-oxidoreductase-subunit-A	unknown	unknown	gnl\|CDD\|180638

Protein	Function_ID	Function_description	E-value
NC_011144.1\|WP_012522365.1\|2026637_2029040_-\|endopeptidase-La	gnl\|CDD\|223542	COG0466, Lon, ATP-dependent Lon protease, bacterial type [Posttranslational modification, protein turnover, chaperones].	0
NC_011144.1\|WP_041373409.1\|2037228_2037441_+\|DUF2188-domain-containing-protein	gnl\|CDD\|378323	pfam09954, DUF2188, Uncharacterized protein conserved in bacteria (DUF2188). This domain, found in various hypothetical bacterial proteins, has no known function.	0.00288647
NC_011144.1\|WP_012522362.1\|2023893_2025297_-\|peptide-MFS-transporter	gnl\|CDD\|340904	cd17346, MFS_DtpA_like, Dipeptide and tripeptide permease A (DtpA)-like subfamily of the Major Facilitator Superfamily of transporters. The DtpA-like subfamily includes four Escherichia coli proteins: dipeptide and tripeptide permeases A (DtpA, TppB or YdgR), B (DtpB or YhiP), C (DtpC or YjdL), and D (DtpD or YbgH). They are proton-dependent permeases that transport di- and tripeptides. DtpA and DtpB display a preference for di- and tripeptides composed of L-amino acids. DtpC shows higher specificity for dipeptides compared to tripeptides, and prefers dipeptides containing a C-terminal lysine residue. The DtpA-like subfamily belongs to the Major Facilitator Superfamily (MFS) of membrane transport proteins, which are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	2.61806e-84
NC_011144.1\|WP_012522361.1\|2022855_2023776_-\|aldo/keto-reductase	gnl\|CDD\|381321	cd19095, AKR_PA4992-like, Pseudomona aeruginosa PA4992 and similar proteins. Pseudomona aeruginosa PA4992 is the prototype of this family. It is a putative aldo-keto reductase that catalyzes the reversible reduction of ketones to the respective alcohols using NAD(P)H as a hydride donor.	5.03382e-87
NC_011144.1\|WP_012522369.1\|2033862_2035263_-\|trehalose-6-phosphate-synthase	gnl\|CDD\|274112	TIGR02400, Alphaalpha-trehalose-phosphate_synthase, alpha,alpha-trehalose-phosphate synthase [UDP-forming]. This enzyme catalyzes the key, penultimate step in biosynthesis of trehalose, a compatible solute made as an osmoprotectant in some species in all three domains of life. The gene symbol OtsA stands for osmotically regulated trehalose synthesis A. Trehalose helps protect against both osmotic and thermal stresses, and is made from two glucose subunits. This model excludes glucosylglycerol-phosphate synthase, an enzyme of an analogous osmoprotectant system in many cyanobacterial strains. This model does not identify archaeal examples, as they are more divergent than glucosylglycerol-phosphate synthase. Sequences that score in the gray zone between the trusted and noise cutoffs include a number of yeast multidomain proteins in which the N-terminal domain may be functionally equivalent to this family. The gray zone also includes the OtsA of Cornyebacterium glutamicum (and related species), shown to be responsible for synthesis of only trace amounts of trehalose while the majority is synthesized by the TreYZ pathway; the significance of OtsA in this species is unclear (see Wolf, et al., ). [Cellular processes, Adaptations to atypical conditions].	0
NC_011144.1\|WP_012522363.1\|2025323_2025896_-\|TMEM165/GDT1-family-protein	gnl\|CDD\|225030	COG2119, COG2119, Predicted membrane protein [Function unknown].	2.05562e-48
NC_011144.1\|WP_012522370.1\|2035728_2036346_-\|ATP-dependent-Clp-protease-proteolytic-subunit	gnl\|CDD\|178955	PRK00277, clpP, ATP-dependent Clp protease proteolytic subunit; Reviewed.	4.48812e-144
NC_011144.1\|WP_012522357.1\|2018787_2019369_-\|NADH-quinone-oxidoreductase-subunit-B	gnl\|CDD\|235797	PRK06411, PRK06411, NADH-quinone oxidoreductase subunit NuoB.	2.23018e-102
NC_011144.1\|WP_012522368.1\|2033239_2033866_+\|HAD-IB-family-hydrolase	gnl\|CDD\|273654	TIGR01490, Uncharacterized_protein_Rv3661/MT3761, HAD-superfamily subfamily IB hydrolase, TIGR01490. This hypothetical equivalog is a member of the IB subfamily (TIGR01488) of the haloacid dehalogenase (HAD) superfamily of aspartate-nucleophile hydrolases. The sequences modelled here are all bacterial. The IB subfamily includes the enzyme phosphoserine phosphatase (TIGR00338). Due to this relationship, several of these sequences have been annotated as "phosphoserine phosphatase related proteins," or "Phosphoserine phosphatase-family enzymes." There is presently no evidence that any of the enzymes in this model possess PSPase activity. OMNI\|NTL01ML1250 is annotated as a "possible transferase," however this is due to the C-terminal domain found on this sequence which is homologous to a group of glycerol-phosphate acyltransferases (between trusted and noise to TIGR00530). A subset of these sequences including OMNI\|CC1962, the Caulobacter crescentus CicA protein cluster together and may represent a separate equivalog. [Unknown function, Enzymes of unknown specificity].	2.03164e-45
NC_011144.1\|WP_012522364.1\|2026187_2026463_-\|HU-family-DNA-binding-protein	gnl\|CDD\|259853	cd13831, HU, histone-like DNA-binding protein HU. This subfamily includes HU and HU-like domains. HU is a conserved nucleoid-associated protein (NAP) which binds non-specifically to duplex DNA with a particular preference for targeting nicked and bent DNA. It is highly basic and contributes to chromosomal compaction and maintenance of negative supercoiling, thus often referred to as histone-like protein. HU can induce DNA bends, condense DNA in a fiber and also interact with single stranded DNA. It contains two homologous subunits, alpha and beta, typically forming homodimers (alpha-alpha and beta-beta), except in E. coli and other enterobacteria, which form heterodimers (alpha-beta). In E. coli, HU binds uniformly to the chromosome, with a preference for damaged or distorted DNA structures and can introduce negative supercoils into closed circular DNA in the presence of topoisomerase I. Anabaena HU (AHU) shows preference for A/T-rich region in the center of its DNA binding site.	1.65433e-33
NC_011144.1\|WP_012522360.1\|2020840_2022766_-\|NAD(P)/FAD-dependent-oxidoreductase	gnl\|CDD\|224983	COG2072, TrkA, Predicted flavoprotein involved in K+ transport [Inorganic ion transport and metabolism].	4.62903e-91
NC_011144.1\|WP_012522372.1\|2037437_2037794_-\|hypothetical-protein	gnl\|CDD\|369610	pfam07946, DUF1682, Protein of unknown function (DUF1682). The members of this family are all hypothetical eukaryotic proteins of unknown function. One member is described as being an adipocyte-specific protein, but no evidence of this was found.	0.000982562
NC_011144.1\|WP_012522374.1\|2038536_2040411_+\|ABC-F-family-ATP-binding-cassette-domain-containing-protein	gnl\|CDD\|223562	COG0488, Uup, ATPase components of ABC transporters with duplicated ATPase domains [General function prediction only].	0
NC_011144.1\|WP_041373408.1\|2035291_2035585_-\|hypothetical-protein	gnl\|CDD\|184052	PRK13435, PRK13435, response regulator; Provisional.	2.72735e-05
NC_011144.1\|WP_012522371.1\|2036438_2037077_-\|DsbA-family-protein	gnl\|CDD\|239323	cd03025, DsbA_FrnE_like, DsbA family, FrnE-like subfamily; composed of uncharacterized proteins containing a CXXC motif with similarity to DsbA and FrnE. FrnE is presumed to be a thiol oxidoreductase involved in polyketide biosynthesis, specifically in the production of the aromatic antibiotics frenolicin and nanaomycins.	1.84589e-51
NC_011144.1\|WP_049758196.1\|2029349_2029799_-\|hypothetical-protein	gnl\|CDD\|380205	NF033203, entero_EhxA, enterohemolysin EhxA. Members of this family are the RTX toxin called enterohemolysin or EhxA, because it is found in enterohemorrhagic Escherichia coli (EHEC) strains such as O157:H7.	3.35054e-16
NC_011144.1\|WP_012522367.1\|2031742_2033005_-\|ATP-dependent-Clp-protease-ATP-binding-subunit-ClpX	gnl\|CDD\|235422	PRK05342, clpX, ATP-dependent Clp protease ATP-binding subunit ClpX.	0
NC_011144.1\|WP_012522359.1\|2020034_2020817_-\|MliC-family-protein	gnl\|CDD\|378282	pfam09864, MliC, Membrane-bound lysozyme-inhibitor of c-type lysozyme. Lysozymes are ancient and important components of the innate immune system of animals that hydrolyze peptidoglycan, the major bacterial cell wall polymer. Various mechanisms have evolved by which bacteria can evade this bactericidal enzyme, one being the production of lysozyme inhibitors. MliC (membrane bound lysozyme inhibitor of c-type lysozyme) of E. coli and Pseudomonas aeruginosa, possess lysozyme inhibitory activity and confer increased lysozyme tolerance upon expression in E. coli. Structural analyses show that the invariant loop of MliC plays a crucial role in the inhibition of the lysozyme by its insertion into the active site cleft of the lysozyme, where the loop forms hydrogen and ionic bonds with the catalytic residues.	1.84144e-17
NC_011144.1\|WP_012522373.1\|2037858_2038278_-\|nucleoside-diphosphate-kinase	gnl\|CDD\|179085	PRK00668, ndk, mulitfunctional nucleoside diphosphate kinase/apyrimidinic endonuclease/3'-; Validated.	3.8519e-89
NC_011144.1\|WP_012522358.1\|2019338_2019716_-\|NADH-quinone-oxidoreductase-subunit-A	gnl\|CDD\|180638	PRK06602, PRK06602, NADH:ubiquinone oxidoreductase subunit A; Validated.	1.28951e-58

>NC_011144.1|WP_049758196.1|2029349_2029799_-|hypothetical-protein
MRGGQGSDAIHGDDGADLLFGDKGDDIVHGGRGEDVIEGGEGSDALAGGQGNDLLRGGDGEDWLSGDRGNDTLSGGPGADVFYGFPGMGRDVVADFDAALGDRIVLAAGATYSASQQGADVVVQLSGEGGAFTLQNVTLASLGDGWIVA
>NC_011144.1|WP_012522365.1|2026637_2029040_-|endopeptidase-La
MSEIKILPILPLRDIVVFPHQPVPLFVGREKSVRALEEAMRAEGKQILLATQKDKDDDDPSPEAIYDVGVVATILQLLKLPDGTVKVLVEGKARAGVTRFTDQADYYEAEIAYVQEDGAGSPEAEALSRAVIEQFENYVKLNKKVPPEALAAIPQIDNPSELADRIAGHLSVKIAEKQQLLEIFNVVKRLEKVYALMEGEISVMQTEKKIRNRVKRQMEKTQREYYLNEQMKAIQRELGEQDDHRDELLELEKRIKKTKLSKEARQKAEAELKKLRNMSPMSAESTVVRNYLDWVLSIPWGKAKQKPIDLQKAEDILNEDHYGLEKVKERILEYLAVQSRVGTLKGPILCLVGPPGVGKTSLGKSIAKATSREFVRVSLGGVRDEAEIRGHRRTYIGSMPGKIIQSMKKAKTTNAFFLLDEIDKMGADWRGDPSSALLEVLDPAQNSTFADHYLEVDYDLSPVMFVTTANSLNMPQPLLDRMEIIRIPGYTEDEKVEIAKRHILPKLTKDHGLKPEEFVVPEETIRDLIRYYTREAGVRSLERELGNLARKTVRDLAREKLLSITVDAERLEKYAGVKKYRYGETDKEDQVGIITGLAYTEFGGDILTIEAVKMPGKGRMTVTGNLKDVMKESISAANSYVRSRATKFGIEPPIFERTDVHIHVPDGATPKDGPSAGAAMATAIVSVLTGIPIKADIAMTGEVTLRGRVTAIGGLKEKLLAALRSGVKTVLIPEENEKDLADIPDNVKSVLEIIPVSTMDQVLAKALVRQPEPIEWDDATPVEVAAEEPDADVEPMVITH
>NC_011144.1|WP_012522364.1|2026187_2026463_-|HU-family-DNA-binding-protein
MTKAELVSAIADKAGLNKAQAKEALDAFIASVSTSLKAGREVRLVGFGSFVPVKRAAGMARNPRTGEKVRRPASQTCRFRVGEALKSTLNS
>NC_011144.1|WP_012522363.1|2025323_2025896_-|TMEM165/GDT1-family-protein
MEQFLISTGVVAVAEIGDKTQLLAIVLAAKFRRPWPIVLGILAATLLNHAAAATLGFAVARFLSGPLFQILVGAGFVAMALWALIPDKEDEDAAAATHGGVFLTTLVAFFLVEIGDKTQIATTLLAARFQEVVLVTAGTTLGMMLANVPAVFLGEAATRVVPLKYVRVGAAVLFGLIGVWVLLAALFGTR
>NC_011144.1|WP_012522362.1|2023893_2025297_-|peptide-MFS-transporter
MTATSVARDGDKAFLGHPKALGYLAFSEAWERFSYYGMQSLLVLYMVKQLLLTPHVEAIAGFETFRAIIGAIYGLPGDASTQQVASTIFGLYTSLVYLTPIAGGFIADRLLGRTRTIIVGALLMSAGHFLMAFDASFLLALLCLVLGTGCFKGNIAGQVGGLYAEGDLRRADAFQIFYLGINAGVIAAPLIAGTLGEGVGWHYGFGAAGVGMLIALVIYLAGRRHLPPDPPLRRAAKADRPKLSAHDWRTIAVLVLLIPVLASSVLVNQQIFNAYLVWADRSVDMTLFGQRLPTTWLITLDSIVSVSFLAGMVVFWRLWAKRFREPDEMGKLTIGAFISVLGALSLAAGAAVAAASGTQVSLWWLIAFEVFNSAAFANMLPVSLALYARASPPAVVGTMIGVYYLHLVIGNQTVGVLGTFLEKMPAANFWLMHAGIAAGAAVVFLVVGRFFARLLSHEAVGAGRTAH
>NC_011144.1|WP_012522361.1|2022855_2023776_-|aldo/keto-reductase
MRHRPLGRTGLTVSELGFGCASWWGKPAFEERQALGLVHRAIDLGVTFFDTGASYSAGEAEPRLGRALKGRDASRLVIATKAGTYHAGGGRIARDVSPAAVVASAERSLKNLGLDALGLLQLHGPAAAELTDELLRALEDLKARGLVRALGVNSFDPALIERVVALPEFDVVMVDYNVLRPEREPLIARAAAAGKGVLAGMALAMGHTRPLLSRLKGPQDLWYAARALARHRGELARGRGFGFLHRQPGISGSQAALAYVLANPDVSCAVFGATRLAHLEENAAASGLTLPQPLMAQIRAAQARLT
>NC_011144.1|WP_012522360.1|2020840_2022766_-|NAD(P)/FAD-dependent-oxidoreductase
MAEQRADLDEILKDAHLPSLMAALVHMTGDPGFIRPEWAPTYNPMEREDIGLSSETQAEMRSEAKAAIQAFLDGRPLQLREPDGATLRRMIDFVAGAPIPEGYADFLTDELALAGKSTKDPQFEQPRLKEAARKLKVLVIGAGMSGILTGIRLSQAGVPFEIVDKNPDVGGTWFENTYPGCRVDNSNHMYSYSFEPNHFWPQHFSTQPVLLSYFRGIAEKYGLRQHIRFETFVEQLTWDEAKAVWRVEMRGKDGQREVVEANAVVTAVGQLNRPRFPDIEGMGSFEGPAFHSAEWRHDVDLKGKRVAVIGTGASAYQFVPEIAPEVASLKVFQRTPPWGLPAPHYHENVPEGMKWLLEHVPYYDKWYRFWLFWMVTDGFLPMVKADPTWNGGPAAVGPENAMLREMCVQSIMAQVADRPDLLPKVVPDYPIGGKRAVLDNGVWLAALKRPNVDLITDRIVRITPKGVVTADGAEHEVDVIIYGTGFQASNFLSFLKVKGRGGRDLHESWGGDARAYLGITNPGFPNLFMIYGPNTNIVVNGSIVFFSECAVRYIVGCLKLLAETGARALEPKREVHDAFNARVDEANKGWAWGSPHVSSWYKNAFGRVSQNWPFGLIDYWRATLAPNPDDYVLEKAPEAVA
>NC_011144.1|WP_012522359.1|2020034_2020817_-|MliC-family-protein
MRAAVLTLALAPLLIGAWGCQRTDAAPPVEAGAAVNPDPKVTIYTCEDGRRIEAGYPDRDTAMVKVDGRPYPLKAAVAASGVRYVGYGLQWWTKGDDARLSRLKEGEDVASDPGVQCWSGEPPPVEPPAPGTPGGLPDDRTPISEAPFTPESAQGAANVVQTFYAYLESGRTEEAARLMRDVAPPDVSRYSEYHAQVGAPGRIEGAAGSLFVEVPVVIYGRLRTGQEVHESGRAVLRRANDVPGSTAAQRRWRIERIELD
>NC_011144.1|WP_012522358.1|2019338_2019716_-|NADH-quinone-oxidoreductase-subunit-A
MNAFLLEYLPIVIFLGIAAALGIAFILAAAIFAPKAPDPEKLSSYECGFNAFDDARMKFDIRFYLVSILFIIFDLEVAFLFPWAVTLMKLPPEASQFAFWSMMTFLGVLTVGFIYEWKKGALEWE
>NC_011144.1|WP_012522357.1|2018787_2019369_-|NADH-quinone-oxidoreductase-subunit-B
MEERRPGMGVIVPAGEAGRTTVEGYDPKLHDPYFDGVSQRLADKGFVTAAADDLITWARTGSLMWMTFGLACCAVEMMQASMPRYDLERYGFAPRASPRQSDVMIVAGTLVNKMAPALRKVYDQMPEPRYVISMGSCANGGGYYYFSYSTVRGCDRVVPVDVYVPGCPPTAEALVYGVLQLQKKIRRTGTIVR
>NC_011144.1|WP_012522367.1|2031742_2033005_-|ATP-dependent-Clp-protease-ATP-binding-subunit-ClpX
MTKAASGDSKSTLYCSFCGKSQHEVRKLIAGPTVFICDECVELCMDIIREEHKISFVKSKDGVPTPKEIREVLDDYVIGQDHAKKVLSVAVHNHYKRLNHATKNNDVELGKANILLIGPTGTGKTLLAQTLARIIDVPFTVADATTLTEAGYVGEDVENIILKLLQAADYNVERAQRGIVYIDEVDKISRKSDNPSITRDVSGEGVQQALLKIMEGTVASVPPQGGRKHPQQEFLQVDTTNILFICGGAFAGLEKIISARGQGTSIGFGAKVADPDERRTGEIFRQVEPDDLLRFGLIPEFIGRLPVIATLDDLDEKALVKILTEPKNAFVKQYVRLFEMENVGLTFTEDALMAVARKAIQRKTGARGLRSILEGVLLDTMYELPTYDGVEEVVVNAEVIEGRAQPLIIYAERRDKGGAA
>NC_011144.1|WP_012522368.1|2033239_2033866_+|HAD-IB-family-hydrolase
MAQVDEPAADAPVVAFDFDGTLTIKDSFTAFLKWRAGPLRWWLGCLRLAPAALAYLFHRDRGRIKAAAVRVFLRGVPHDRLESDARRFAADHARRLLRPDAVATWKRWRERGARIVIVTASPDIVVAPFGRGLGAHLILGTQLSFDAQNRVLGAFSGPNCRGAEKVVRLHEVFGPDLRLAAAYGDTSGDTEMLAIADEAGFRVFKGRP
>NC_011144.1|WP_012522369.1|2033862_2035263_-|trehalose-6-phosphate-synthase
MGRLIVVSNRVGQPDQSGGPSVGGLAMALGAALREYNGVWFGWSGRTVETFTGGLSVQRGQGATVATVDLEEQDRQEYYNGYANRTLWPLFHYRIDLSAYERSFNEGYARVNARFAQTLLPLLKPDDFIWVHDYHLIPLGRELRRRGVKNRIGFFLHIPWPARRLFATLPFHRELVEAVFDYDLVGFQSEDSLSAFEDYVEREAGGTVGPNGRFEAFGRSLQAGVFPIGLDTKAFLEGAATEAASAWRDRMRVSLAGRRMIIGVDRLDYSKGLEERFLAYEEYLSHAPEALEQVFLLQIATPSRDEVAAYQEIRARLDAVTGRINGAFATPDWVPIRYVNRSYRRDELAGIYGVAAIGLVTPLRDGMNLVAKEYVAAQPPEDPGVLILSRFAGAAEQMGEALIVNPFSREEVSDAIREGLAMPLKERVRRWEALMAGVRRDDVDAWRDAFVSALRAVPQRELPPAA
>NC_011144.1|WP_041373408.1|2035291_2035585_-|hypothetical-protein
MRDLNELLEQCDQFSTVLIARKSPESTDSLVQLLVDAGVNVLGPVDTAARALAIVAQTPADFAVVTPELAGKRNGAELARRLEDTWGVPSVVVAPAA
>NC_011144.1|WP_012522370.1|2035728_2036346_-|ATP-dependent-Clp-protease-proteolytic-subunit
MRDPVTTALGLVPMVVEQTSRGERAYDIFSRLLKDRIVFLAGPVEDGMASLICAQLLHLEAENPKKEIQMYINSPGGVVTSGLAIYDTMQYIKSPVITLCLGMAASMGSFLLMAGEKGQRIALPNSRIMVHQPSGGYSGKATDIQRHAEDIIKTKRRLNEIYAKHTGQPIEAVEETLDRDFFMTAQEAKDWGLVDHVWEKRDNES
>NC_011144.1|WP_012522371.1|2036438_2037077_-|DsbA-family-protein
MNAPHLIYFADPMCSWCYGFSPVIEDIHRAFGRALPIRVVMGGLRPGTDTPMTDEAKAQVTGHWRHVHEATGLPFDEAVLDREGFLYDTDPAARAVVVVRREGEELAAGYLGRLQRAFYAENRDVTSAETLADLAAELGVDRERFLAQWDAEDAKMETWRDYAISQRAGVTGFPTLVAGPNAEGAFGVVTRGYAPSEPVVATLRDWISSIAA
>NC_011144.1|WP_041373409.1|2037228_2037441_+|DUF2188-domain-containing-protein
MVQYAVTLKDGDWTVFGEGEPLARGLTRSAAIQMAKDLAFEAEERGETVELLIQGYYGEMSRKVTGVADD
>NC_011144.1|WP_012522372.1|2037437_2037794_-|hypothetical-protein
MRESKLPDFSERLAAQAEARKALLEKFKPKPTVRAEGEVFETREQRKARELAEVRAKRAAEKEAARLAKEKAEEEARLARENDEEFQLQLKRDERKARKAAAKAEARAKREMKAQGRR
>NC_011144.1|WP_012522373.1|2037858_2038278_-|nucleoside-diphosphate-kinase
MTERTFSIIKPDATRRNLTGKVNAVIEDAGLRIVAQKRIRMSRAQAEKFYEVHKERPFFGELVEFMTSAPVVVQVLEGENAVARYREVMGATNPAQAADGTIRKLYAESVGENSVHGSDSLENAKIEIAQFFTEDEIVG
>NC_011144.1|WP_012522374.1|2038536_2040411_+|ABC-F-family-ATP-binding-cassette-domain-containing-protein
MLQINDLVFDAWGRRFFDQASVTLPKDAKVGLVGRNGVGKSTLFRLILGEFTPGSGEIGLPRAARIGSVDQEHPATPVPLLETVLAADVERASLLERLETATPEEMGEIYNRLIAIDADRAPSRAAEILSGLGFSEPDLARPMAEFSGGWRMRVALAAALFAQPDLLLLDEPTNYLDLEGALWLEARLKKYPHTAIVISHDRELLNNSVDHILHLKDGKLELYAGGYDSFERQLTEKLRLQEAARVKIEAKRAHMQSFVDRFRAKASKARQAQSRLKAIAKLPPVSAVVEEHVAPFLLPSPERPLPPPLLRLEEAAVGYGGPPILKKLDLRLDLDDRIGLLGVNGAGKSTFAKLVAGALQPEAGRLLRSQRLKVGWFHQHQIEAMDADDTPLEIIRRAMPDATEAKRRSVIAQFGFSHEKVETKVGSLSGGERARLLLNLVAMEAPHLLILDEPTNHLDIDSRRALLEALNDYEGAVILITHDRSLMELVADRLWLAADGTIQPFDGDMEDYARFVLDRARIAARAPTQVKAEAPPPPPPPPAAKSKVPTGPARRRAEAAEAALGKATEALAAIDAALTDPQVFVKDPAKAADLGRKREAAQAAVEAAELEWLEAQEAYEALRG

You can click texts colored in the table to view more detailed information

Click the colored protein region to show detailed information

Crispr_ID: NC_011144_4

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_011144_4

2855370-2855464

Orphan

Consensus_repeat	Method
TTCGTGCTCAGGTCGTTGTTGTT	CRISPRCasFinder

1 spacers

The CRISPR arrays of NC_011144_4

>merge|NC_011144|4|2855370-2855464|CRISPRCasFinder
TTCGTGCTCAGGTCGTTGTTGTTGAGCCCGGACACGTCCGTCGACGCGTCGGTGTTGGTCGAGTTGTCGTCATTCGAGCTCAGGTCGTTGTTGTT

>NC_011144|4|3|2855370-2855464|CRISPRCasFinder
TTCGTGCTCAGGTCGTTGTTGTT	GAGCCCGGACACGTCCGTCGACGCGTCGGTGTTGGTCGAGTTGTCGTCA
TTCGAGCTCAGGTCGTTGTTGTT

Protein	Signature genes	Signature genes Name	Protein_function
NC_011144.1\|WP_041374224.1\|2851775_2853014_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|377222
NC_011144.1\|WP_012523047.1\|2865489_2866827_+\|sorbosone-dehydrogenase-family-protein	unknown	unknown	gnl\|CDD\|225044
NC_011144.1\|WP_187149082.1\|2856176_2856803_+\|helix-turn-helix-domain-containing-protein	unknown	unknown	gnl\|CDD\|223736
NC_011144.1\|WP_083771028.1\|2850331_2851462_-\|SDR-family-oxidoreductase	unknown	unknown	gnl\|CDD\|187541
NC_011144.1\|WP_012523030.1\|2846585_2847674_+\|endo-1,4-beta-xylanase	unknown	unknown	gnl\|CDD\|366032
NC_011144.1\|WP_012523042.1\|2860480_2861284_-\|two-pore-domain-potassium-channel-family-protein	unknown	unknown	gnl\|CDD\|369572
NC_011144.1\|WP_012523029.1\|2845663_2846356_-\|cellulose-biosynthesis-protein-BcsS	unknown	unknown	gnl\|CDD\|379916
NC_011144.1\|WP_041373554.1\|2853173_2853713_-\|hypothetical-protein	unknown	unknown	unknown
NC_011144.1\|WP_012523031.1\|2847686_2848826_-\|NAD-dependent-epimerase/dehydratase-family-protein	unknown	unknown	gnl\|CDD\|187566
NC_011144.1\|WP_012523032.1\|2848838_2850287_-\|glycosyltransferase	unknown	unknown	gnl\|CDD\|379305
NC_011144.1\|WP_012523045.1\|2863143_2864217_-\|acyl-CoA/acyl-ACP-dehydrogenase	unknown	unknown	gnl\|CDD\|224871
NC_011144.1\|WP_012523044.1\|2861659_2863147_+\|amidase	unknown	unknown	gnl\|CDD\|181154
NC_011144.1\|WP_012523035.1\|2853709_2854462_-\|C39-family-peptidase	unknown	unknown	gnl\|CDD\|239103
NC_011144.1\|WP_012523046.1\|2864218_2865385_-\|acyl-CoA-dehydrogenase-family-protein	unknown	unknown	gnl\|CDD\|173841
NC_011144.1\|WP_012523041.1\|2859328_2860414_-\|substrate-binding-domain-containing-protein	unknown	unknown	gnl\|CDD\|270372
NC_011144.1\|WP_041373553.1\|2844391_2845501_-\|endo-1,4-beta-xylanase	unknown	unknown	gnl\|CDD\|366032
NC_011144.1\|WP_012523036.1\|2854478_2854916_-\|hypothetical-protein	unknown	unknown	unknown
NC_011144.1\|WP_012523039.1\|2856927_2857659_+\|Crp/Fnr-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|223736
NC_011144.1\|WP_012523043.1\|2861381_2861576_+\|DUF3008-family-protein	unknown	unknown	gnl\|CDD\|314387
NC_011144.1\|WP_012523040.1\|2858621_2859092_+\|thioredoxin-family-protein	unknown	unknown	gnl\|CDD\|239245

Protein	Function_ID	Function_description	E-value
NC_011144.1\|WP_041374224.1\|2851775_2853014_+\|hypothetical-protein	gnl\|CDD\|377222	pfam04102, SlyX, SlyX. The SlyX protein has no known function. It is short less than 80 amino acids and is found close to the slyD gene. The SlyX protein has a conserved PPH(Y/W) motif at its C-terminus. The protein may be a coiled-coil structure.	1.1369e-06
NC_011144.1\|WP_012523047.1\|2865489_2866827_+\|sorbosone-dehydrogenase-family-protein	gnl\|CDD\|225044	COG2133, COG2133, Glucose/sorbosone dehydrogenases [Carbohydrate transport and metabolism].	4.38092e-101
NC_011144.1\|WP_187149082.1\|2856176_2856803_+\|helix-turn-helix-domain-containing-protein	gnl\|CDD\|223736	COG0664, Crp, cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms].	3.45313e-19
NC_011144.1\|WP_083771028.1\|2850331_2851462_-\|SDR-family-oxidoreductase	gnl\|CDD\|187541	cd05230, UGD_SDR_e, UDP-glucuronate decarboxylase (UGD) and related proteins, extended (e) SDRs. UGD catalyzes the formation of UDP-xylose from UDP-glucuronate; it is an extended-SDR, and has the characteristic glycine-rich NAD-binding pattern, TGXXGXXG, and active site tetrad. Extended SDRs are distinct from classical SDRs. In addition to the Rossmann fold (alpha/beta folding pattern with a central beta-sheet) core region typical of all SDRs, extended SDRs have a less conserved C-terminal extension of approximately 100 amino acids. Extended SDRs are a diverse collection of proteins, and include isomerases, epimerases, oxidoreductases, and lyases; they typically have a TGXXGXXG cofactor binding motif. SDRs are a functionally diverse family of oxidoreductases that have a single domain with a structurally conserved Rossmann fold, an NAD(P)(H)-binding region, and a structurally diverse C-terminal region. Sequence identity between different SDR enzymes is typically in the 15-30% range; they catalyze a wide range of activities including the metabolism of steroids, cofactors, carbohydrates, lipids, aromatic compounds, and amino acids, and act in redox sensing. Classical SDRs have an TGXXX[AG]XG cofactor binding motif and a YXXXK active site motif, with the Tyr residue of the active site motif serving as a critical catalytic residue (Tyr-151, human 15-hydroxyprostaglandin dehydrogenase numbering). In addition to the Tyr and Lys, there is often an upstream Ser and/or an Asn, contributing to the active site; while substrate binding is in the C-terminal region, which determines specificity. The standard reaction mechanism is a 4-pro-S hydride transfer and proton relay involving the conserved Tyr and Lys, a water molecule stabilized by Asn, and nicotinamide. Atypical SDRs generally lack the catalytic residues characteristic of the SDRs, and their glycine-rich NAD(P)-binding motif is often different from the forms normally seen in classical or extended SDRs. Complex (multidomain) SDRs such as ketoreductase domains of fatty acid synthase have a GGXGXXG NAD(P)-binding motif and an altered active site motif (YXXXN). Fungal type ketoacyl reductases have a TGXXXGX(1-2)G NAD(P)-binding motif.	0
NC_011144.1\|WP_012523030.1\|2846585_2847674_+\|endo-1,4-beta-xylanase	gnl\|CDD\|366032	pfam00331, Glyco_hydro_10, Glycosyl hydrolase family 10.	8.28609e-76
NC_011144.1\|WP_012523042.1\|2860480_2861284_-\|two-pore-domain-potassium-channel-family-protein	gnl\|CDD\|369572	pfam07885, Ion_trans_2, Ion channel. This family includes the two membrane helix type ion channels found in bacteria.	7.32792e-09
NC_011144.1\|WP_012523029.1\|2845663_2846356_-\|cellulose-biosynthesis-protein-BcsS	gnl\|CDD\|379916	pfam17036, CBP_BcsS, Cellulose biosynthesis protein BcsS. This is a family of bacterial cellulose biosynthesis proteins. Cellulose is necessary for biofilm formation in bacteria. (Roemling U. and Galperin M.Y. "Bacterial cellulose biosynthesis. Diversity of operons and subunits" (manuscript in preparation)).	1.98104e-09
NC_011144.1\|WP_012523046.1\|2864218_2865385_-\|acyl-CoA-dehydrogenase-family-protein	gnl\|CDD\|173841	cd01152, ACAD_fadE6_17_26, Putative acyl-CoA dehydrogenases similar to fadE6, fadE17, and fadE26. Putative acyl-CoA dehydrogenases (ACAD). Mitochondrial acyl-CoA dehydrogenases (ACAD) catalyze the alpha, beta dehydrogenation of the corresponding trans-enoyl-CoA by FAD, which becomes reduced. The reduced form of ACAD is reoxidized in the oxidative half-reaction by electron-transferring flavoprotein (ETF), from which the electrons are transferred to the mitochondrial respiratory chain coupled with ATP synthesis. The ACD family includes the eukaryotic beta-oxidation, as well as amino acid catabolism enzymes. These enzymes share high sequence similarity, but differ in their substrate specificities. The mitochondrial ACD's are generally homotetramers and have an active site glutamate at a conserved position.	2.31676e-123
NC_011144.1\|WP_012523031.1\|2847686_2848826_-\|NAD-dependent-epimerase/dehydratase-family-protein	gnl\|CDD\|187566	cd05256, UDP_AE_SDR_e, UDP-N-acetylglucosamine 4-epimerase, extended (e) SDRs. This subgroup contains UDP-N-acetylglucosamine 4-epimerase of Pseudomonas aeruginosa, WbpP, an extended SDR, that catalyzes the NAD+ dependent conversion of UDP-GlcNAc and UDPGalNA to UDP-Glc and UDP-Gal. This subgroup has the characteristic active site tetrad and NAD-binding motif of the extended SDRs. Extended SDRs are distinct from classical SDRs. In addition to the Rossmann fold (alpha/beta folding pattern with a central beta-sheet) core region typical of all SDRs, extended SDRs have a less conserved C-terminal extension of approximately 100 amino acids. Extended SDRs are a diverse collection of proteins, and include isomerases, epimerases, oxidoreductases, and lyases; they typically have a TGXXGXXG cofactor binding motif. SDRs are a functionally diverse family of oxidoreductases that have a single domain with a structurally conserved Rossmann fold, an NAD(P)(H)-binding region, and a structurally diverse C-terminal region. Sequence identity between different SDR enzymes is typically in the 15-30% range; they catalyze a wide range of activities including the metabolism of steroids, cofactors, carbohydrates, lipids, aromatic compounds, and amino acids, and act in redox sensing. Classical SDRs have an TGXXX[AG]XG cofactor binding motif and a YXXXK active site motif, with the Tyr residue of the active site motif serving as a critical catalytic residue (Tyr-151, human 15-hydroxyprostaglandin dehydrogenase numbering). In addition to the Tyr and Lys, there is often an upstream Ser and/or an Asn, contributing to the active site; while substrate binding is in the C-terminal region, which determines specificity. The standard reaction mechanism is a 4-pro-S hydride transfer and proton relay involving the conserved Tyr and Lys, a water molecule stabilized by Asn, and nicotinamide. Atypical SDRs generally lack the catalytic residues characteristic of the SDRs, and their glycine-rich NAD(P)-binding motif is often different from the forms normally seen in classical or extended SDRs. Complex (multidomain) SDRs such as ketoreductase domains of fatty acid synthase have a GGXGXXG NAD(P)-binding motif and an altered active site motif (YXXXN). Fungal type ketoacyl reductases have a TGXXXGX(1-2)G NAD(P)-binding motif.	5.3101e-77
NC_011144.1\|WP_012523032.1\|2848838_2850287_-\|glycosyltransferase	gnl\|CDD\|379305	pfam13632, Glyco_trans_2_3, Glycosyl transferase family group 2. Members of this family of prokaryotic proteins include putative glucosyltransferases, which are involved in bacterial capsule biosynthesis.	6.64927e-19
NC_011144.1\|WP_012523045.1\|2863143_2864217_-\|acyl-CoA/acyl-ACP-dehydrogenase	gnl\|CDD\|224871	COG1960, CaiA, Acyl-CoA dehydrogenases [Lipid metabolism].	9.95341e-42
NC_011144.1\|WP_012523044.1\|2861659_2863147_+\|amidase	gnl\|CDD\|181154	PRK07869, PRK07869, amidase; Provisional.	2.41488e-148
NC_011144.1\|WP_012523035.1\|2853709_2854462_-\|C39-family-peptidase	gnl\|CDD\|239103	cd02423, Peptidase_C39G, A sub-family of peptidase family C39. Peptidase family C39 mostly contains bacteriocin-processing endopeptidases from bacteria. The cysteine peptidases in family C39 cleave the "double-glycine" leader peptides from the precursors of various bacteriocins (mostly non-lantibiotic). The cleavage is mediated by the transporter as part of the secretion process. Bacteriocins are antibiotic proteins secreted by some species of bacteria that inhibit the growth of other bacterial species. The bacteriocin is synthesized as a precursor with an N-terminal leader peptide, and processing involves removal of the leader peptide by cleavage at a Gly-Gly bond, followed by translocation of the mature bacteriocin across the cytoplasmic membrane. Most endopeptidases of family C39 are N-terminal domains in larger proteins (ABC transporters) that serve both functions. The proposed protease active site is conserved in this sub-family of proteins with a single peptidase domain, which are lacking the nucleotide-binding transporter signature.	6.86439e-51
NC_011144.1\|WP_041373553.1\|2844391_2845501_-\|endo-1,4-beta-xylanase	gnl\|CDD\|366032	pfam00331, Glyco_hydro_10, Glycosyl hydrolase family 10.	4.60517e-84
NC_011144.1\|WP_012523041.1\|2859328_2860414_-\|substrate-binding-domain-containing-protein	gnl\|CDD\|270372	cd13654, PBP2_phosphate_like_2, Substrate binding domain of putative ABC-type phosphate transporter, a member of the type 2 periplasmic binding fold superfamily. This subfamily contains uncharacterized phosphate binding domains found in PstS proteins that serve as initial receptors in the ABC transport of phosphate in eubacteria and archaea. After binding the ligand, PstS interacts with a cognate membrane transport complex comprised of two integral membrane domains and two cytoplasmically located ATPase domains. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis. The PstS proteins belong to the PBP2 superfamily of periplasmic binding proteins that differ in size and ligand specificity, but have similar tertiary structures consisting of two globular subdomains connected by a flexible hinge. They have been shown to bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap.	9.33528e-84
NC_011144.1\|WP_012523039.1\|2856927_2857659_+\|Crp/Fnr-family-transcriptional-regulator	gnl\|CDD\|223736	COG0664, Crp, cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms].	1.11685e-17
NC_011144.1\|WP_012523043.1\|2861381_2861576_+\|DUF3008-family-protein	gnl\|CDD\|314387	pfam11450, DUF3008, Protein of unknwon function (DUF3008). This is a bacterial family of uncharacterized proteins.	5.74637e-15
NC_011144.1\|WP_012523040.1\|2858621_2859092_+\|thioredoxin-family-protein	gnl\|CDD\|239245	cd02947, TRX_family, TRX family; composed of two groups: Group I, which includes proteins that exclusively encode a TRX domain; and Group II, which are composed of fusion proteins of TRX and additional domains. Group I TRX is a small ancient protein that alter the redox state of target proteins via the reversible oxidation of an active site dithiol, present in a CXXC motif, partially exposed at the protein's surface. TRX reduces protein disulfide bonds, resulting in a disulfide bond at its active site. Oxidized TRX is converted to the active form by TRX reductase, using reducing equivalents derived from either NADPH or ferredoxins. By altering their redox state, TRX regulates the functions of at least 30 target proteins, some of which are enzymes and transcription factors. It also plays an important role in the defense against oxidative stress by directly reducing hydrogen peroxide and certain radicals, and by serving as a reductant for peroxiredoxins. At least two major types of functional TRXs have been reported in most organisms; in eukaryotes, they are located in the cytoplasm and the mitochondria. Higher plants contain more types (at least 20 TRX genes have been detected in the genome of Arabidopsis thaliana), two of which (types f amd m) are located in the same compartment, the chloroplast. Also included in the alignment are TRX-like domains which show sequence homology to TRX but do not contain the redox active CXXC motif. Group II proteins, in addition to either a redox active TRX or a TRX-like domain, also contain additional domains, which may or may not possess homology to known proteins.	2.78197e-12

>NC_011144.1|WP_012523036.1|2854478_2854916_-|hypothetical-protein
MSRIDVVRASALAGLFALVGAGGAWASEPLQEALVAPAAAPAAEPDLFGLRPNLGETLTPEDGTESDEALGAISGRGDVIVALTDQDLTAVSTGNTITADLVNSGNISLQDNALSGFGGVGNFLMNTGHNNSLQSNVSVTIIVTQ
>NC_011144.1|WP_012523035.1|2853709_2854462_-|C39-family-peptidase
MRRRRDRSRIVALAAALTALAAAAPAVAQVQFYGEASGARVRVMTWRDIPFRTVVRQEHDYSCGSAALATLLTYHYGRPTTEAEAFTRMYAAGDQETIRRVGFSMLDMKRYLAAEGLRADGFRMSIDDIGKEGVPVIALIQMGAYRHFVVVKGVVGDRVLVGDPALGLRIFTRAQFNAMWNGIAFALHDTPAVGRGRFNVANEWSPWSTAPLRARADATDTLNALTLHQLPFYQITPIMVLGSVAPGGGL
>NC_011144.1|WP_041373554.1|2853173_2853713_-|hypothetical-protein
MKLVTLLAAASAAVALNLGALPAASFDYETVDDAVLQDNRGGMLLAGGVPFQFGAVMSTYENGMLSLQTHLVWTPDGAVVQQIPGDGVIRLDDAALQNMAGAGQTFQTVGGSFVAHDLTQGQLTNFLLNTQSGRDFRQDLELTLVLPGFVGVQNDMGRQLTGLRLVDDLAASSISALGG
>NC_011144.1|WP_041374224.1|2851775_2853014_+|hypothetical-protein
MAGWSTAASAQAPAAPDARIEALQGQLARQAAQLAEQQQALAEQQAALERQRVELERLQALSEAVLGAAYGRGQPAAGPAAAPAGPPPPVQTVPPSPPKVGAPPPEEAPRVDISAVPEGYGVLTPRNHWVVEPSIDFTHGSANRLVFRGVEIVTGIQIGVIEASDADRNAVSGALAVRYGLTDRLEVEGRVPYLYRDDRVTTLAQRDETITRTFTLQGQDIGDVELAARYQINDGRRGWPIFIAGLRYKSDTGTSPFEIERDQFGVATELATGSGFWGLEGSLSFLYPTDPVVIFGGLSYLSHQPKDINKVVGEVLVRKVDPGDTIGLNAGFGFALNPRFSFSLGYKHSYIFPTKSVYGNTLQESDSLQVGAFTFGWSYALTDRISISNAYELGTTSDAPDMRIVLRFPIRF
>NC_011144.1|WP_083771028.1|2850331_2851462_-|SDR-family-oxidoreductase
MGANGSAGGSPGAEGDRRRGRGEVSAGGAQITETRTFSDLGSGPRELGRGKVVAVTGGAGFIGSHLCETLLASGARVVCIDNFQTGSRDNVDRLIESPNFSVVYHDILEPFPNDLPKFDEIFNFACPASPVHYQADRVRTALVCAVGARNVLERAARDGARALQASTSEVYGDPDIHPQPESYRGHVNPIGPRACYDEGKRFAESLFTDFGAQSGVTVKIVRIFNTYGPRMQPHDGRVISNFVVQALAGEDLTLYGDGSQTRSFCYVDDLVDGCLRLMASPSDLSQPVNLGNPVETTVAEVAELILELTGSRSRIVRRPLPVDDPRRRKPDITLAETRLGWRPQVPLREGLERTIAHAVRREHRASFGDAAVAAHG
>NC_011144.1|WP_012523032.1|2848838_2850287_-|glycosyltransferase
MLFEPGAVDVLVVLFAISQILYALAFVNDFYLFSLPVNRVQISDARDTPERDYPDIVMFYPVLNELESTMRTTLIALDRVLYPAGKKRVIAIPNWDDARTLASLKRLQFEFPFLELLEVPATSDPSWARVWKAWDANEKAYWWHVGRRAGDRNLPPKKTRQLIYAFYRTYEEGEGREFLVNYIDADSCPPPNHFMAAVAGMRRYDVLQAKNVAGNLNASLAASWHSFDHMNWDGMKYAHLSANGRQPYWMLGKGLFFRASDLYELGSFHPWITIEDPEVGMRFWKNGKRLGVIESPLIEEVPLTFGRGITQRKRWVCGFFQSLGEPTRRLGFSAWERVKAWLIFLPCLSLWVNLIGYPVGAWAMWALVRGENVLPLWLVILAAINIVAFAVSLTVLYVNTWKRTALVLERKRDRVAYMLRVNPLFVAAWWLMWLIPLGIGLWMYLRDLGQVWERTEKINANEDLITVHQGGAAHQGAVYRPA
>NC_011144.1|WP_012523031.1|2847686_2848826_-|NAD-dependent-epimerase/dehydratase-family-protein
MPERHALITGGAGFIGSHLTDVLLDRGFQVTVLDCLLPQVHADGELDAEGWPTYLNPAARRIRGDILDPGVFEAALEGVTHLVHLAASVGVGQSMTNIVDYTRNNTMGAAVMLEALSKGRHAVERIAVASSMSIYGEGEYRAPSTGREVVPGLRSHEQLKARRWDLEADGERLEPVPTSEDKRLQPASIYAINKRDHEDMFLAVGRALEIPTVALRLFNAYGSRQALSNPYTGVAAIFISRLLNDQPPLVFEDGEQLRDFVHVRDVADAFATVLESDAQVWDAYNVGSGQPVRIVEMAAALALLLRKNIAPERLDRYRVGDIRHCFPDIRRIERDFGFRPRRSFETGMEELIDWVARAPRPQDRAAQSLAELTESRLVV
>NC_011144.1|WP_012523030.1|2846585_2847674_+|endo-1,4-beta-xylanase
MRLLDRRGLLAGLAAGPLLLAAPRPGAQALPNGPSLAAAAARGGRYFGAAARIDQIRAERALRRTVLRDCAWITPEFHMNWDYVAPRSGAWNFRDADGLVAFAGEAGLKVRGHSLIWDQSTPAWAAAEMVERRDWETVARHFQRVMGRWGERVQAWDVVNEPIARDGRGLLPSMFLEAYGPDYVRRAFDEARALQPQARLAVNDYGFDYDNPVEEARRGSFLRLLEDLKAKGAPVDEVGIQAHLDLGKGPLRRRIVAPFLREIGQMGYRIVISELDVRERDFTLPLVERDRRVADEVRAYLEIALAEPAVEGVVTWGLSDRHSWLQDDEAAALGGVNRGLPYDHGLRPKPMYWALRDTLAAA
>NC_011144.1|WP_012523029.1|2845663_2846356_-|cellulose-biosynthesis-protein-BcsS
MAGSTLARAMGLALVTAAAGWPAGNTAAQVPATVFGGAGVGADEMAYLGATVPVGGSGFALRGIVSTSQYKYRSAATRITSDQVQGEVSALYQRAGPNGYFDLGVGARYTDTDLSPNDPGNRSQGDEWDVVLSMSGQTAPGPWRAAGFASYAVDSEDYYVRAELTRAVRPSVRLGLEAVLDGDPNYDRRRAGVLLGVSTSPRWEAHIAVGASDSKARDGAYASIGFRRSF
>NC_011144.1|WP_041373553.1|2844391_2845501_-|endo-1,4-beta-xylanase
MMALAGAAALAGGAAPAGESLDALARRKGVRFGTAVGLGETRGNSFDDPAFRALIAHECGLIVAENEHKWYVLRPSADSYDFGPADRLAAFAAERGLGLRGHTLLWSRDEFSAKWLAAHDFGPRPRAAAERMLVEHIRAVTARYPQVDSWDVVNETIDPATGELRDTILGRQIGPEIVEIAFHEAKAAAPKARLIYNDYMNFGDEEAVHRKGVLKLLERLKARGVPIDALGVQGHIGGGVDSTPVERFTAADQRDWRAFLDEVRGMGLDLLITEFDVNCRAMPADLARRDAEVAALGGDFLGMMLDYRELKQVLVWGLADGASWLQGTTPRADGLPKRPTPYDDRLRSKPLREAMAAAFRAAPERTAWA
>NC_011144.1|WP_187149082.1|2856176_2856803_+|helix-turn-helix-domain-containing-protein
MERYPPGVTLHAGTGLSARKVIVSGWASETRILHDGRRQIFSFLLPGDAVDLARAGSIGRRSVVTLTRLETVDAEVLLNRSDATRETVREAIQTAMRRKEERLFDHMARIGRLTTKERVLNLLLELHDRLEAVGLAKQGSFRIPLTQEVFADTLGLSIVHINRTLQHLRREGLITLKAGTVTLHDRRRLAALCCYQMTGEDAESPRLI
>NC_011144.1|WP_012523039.1|2856927_2857659_+|Crp/Fnr-family-transcriptional-regulator
MSELDPSTEAWLNLALDHALAGLHHNGGLAPEAGAMLRQSVRRLERYPAGALVNASTRKPEVKWIVTGWASEMRILPDSRRQICSFLIPGDVFTARPANSSSCGVVALTRMDCADVERTLDGSPEPIRPAVWEAVARSLSLMLERRYEHITRLGQLGAAERLVHLLLELRERLETVGLAAPDKFRLPLTQEHLADALGLSIVHVNRTLRHLRAQRLLEVKFGGVALLQPARLADIAGRFDEPV
>NC_011144.1|WP_012523040.1|2858621_2859092_+|thioredoxin-family-protein
MNAIPIEEPAAAGSGRRGGRSNPAKQAAGQRGAAGARNAFPQTITDGQLSALLAEGRGTLLIDVSASSSGLGRTMDEQFRLAAKALRSRVRMLTIDVHRHPAAAIELSVNAFPTLILLRGGQAIARHAGVMSAEMIVNWTRQALADALRARRTPRA
>NC_011144.1|WP_012523041.1|2859328_2860414_-|substrate-binding-domain-containing-protein
MRFPILTATVALAALSLAACGQGGGSPAGQGAAPKGGAQGQVWAAGSSTVFPFATRVAETVARTTGGAPAKVESLGTGGGIKLFCGGAGRNFPDVANASRRMKKSEWEACQANGVTDILEVKIGYDGIVIANAKNAPTFHLTREQIYRALAAEVPQGSGFATNTAATWSAVAPGLPNERIVAYGPPPTSGTRDAFVELAMEKGAEKVPAMAALKSSDEEAFKQRAHTLRKDGAWIDAGENDNVIVQTLEKTPNAVGVFGYSFLENNMDKVKAADIEGVSPTLENISTGKYPLSRSLYIYVKRANIGVTPGLKEFVDGFLSEAAVGRGGYLLQRGLIPLPADELTAQRDAAKALTPMTAPAS
>NC_011144.1|WP_012523042.1|2860480_2861284_-|two-pore-domain-potassium-channel-family-protein
MAEPATETGTRRRLPRLRVRLRELYYGRSPRAVRFRLSVIALDFLLIGFFIASPFLREYPAYLFIDYFVALILALDLAARALAYVSLRDWLRRPSVWVDLFVLVTLLFPLWLFNLAFLRVLRLWSLFHSDFFWETVGRRYDDTRWEDVTKAVATLVTFVFVSTGFVYASFAREHPGISGYLDALYFTVTALTTTGFGDITLPGAWGKLLAIIIMISGITLFVRLAQTLIRPYKVRFTCPTCGLMRHDADAVHCKACGTLLNIPNDEV
>NC_011144.1|WP_012523043.1|2861381_2861576_+|DUF3008-family-protein
MPAKSAAQQKAAGAALSAKRGDTPKSKLKGASKSMADSMSEKELEKMASTKRKGKPEHVSDRRS
>NC_011144.1|WP_012523044.1|2861659_2863147_+|amidase
MIRLSRRAFAGAPLALAACATVPERAFRPTPGWPDATETAAMIRRGEITAGQAVRSAIDRTLALQPRLNFLVASDFDRALARAATGPGDGPFAGVPFLVKDLDDYRGLPTRSGSFSQLPLPPAQGQGPLIDAFERAGVVVIGKSATPEYGFLPTTEPAAFGPTRNPWDPTRSSGGSSGGAAAAVAAGAVPFAHASDGGGSIRIPASCCGLFGLKPSRGRMVGAREQTKISDLSVDHVLTRSVRDSAAMFALTEDAGEGAQHPPVGLVTAPLRRRLRVGLVMEGMAGKAPSPEVRAATEASARLLESLGHTVVPTRWPTGPEFTQDFLLLWASGAAQLAGAIGKAAGRQPDTTLLEPFSLGMAEMFAKAPPGALGQAMERLHAAAMAYDPWFVGNGLDVVMSPVLSAPPPPLGWVGPGVPFDTLVERLTEYVGYTTYHNVTGAPAMSVPLNWIGAGLPVGTQFAARVGHEALLFQLAYQLEAAQPWAGRLPPVRAL
>NC_011144.1|WP_012523045.1|2863143_2864217_-|acyl-CoA/acyl-ACP-dehydrogenase
MRFALSEDQVLLQDSLAKALAELAPLERVRRFADDNEPCAGDIWAGLAELGLPGLLIDEAHGGLGLGLIEAALAAEALGRTVAPTPFLGSAVLAPLALKLAGSAEQQARWLPSLAAGEITAGVAIAEPIAGARDGAGVDAVAGRLTGRALFAVGAEGADLLVVADRTGGLHLAESAEATAPMRTIDATRRLTEISFKATPAEPLASNGALERLRDAAWVMLAADTVGAAGAMLGKAVGYAQERRQFGRVIGSFQAVKHLCAEMAAEIEPARALVWYAAYAFDHAPDEAPLMAAHAKAHTSEIGRFVARTATEVHGGIGITDLLGLHYWFKRIGLNRQLFGGPERVRETAARLQGLAA
>NC_011144.1|WP_012523046.1|2864218_2865385_-|acyl-CoA-dehydrogenase-family-protein
MDLTLTPELSAFREEVRAFLAAHRGEYEAGQPKDPLAWQRLLIEHGYAARTIPKAYGGFGAQPDILKARIIAEAFIAAGAPRGLANQGISMLVPTLLEVGSEDQKTRWIGPTLRGEVVWCQGYSEPGAGSDLASLQTRAVEDGEDFVISGSKIWTSTAHLADMMFCLVRTEPDKPKHEGISYVLIPMDTPGIEVRPLKTMTGYAEFNEVFFTDVRVPQANVVGGRGRGWQVANTTLKHERGMLGDPNATEARLAALIELMKTETVDGERIIDNPVFRDRLMQLQARVFAMKFNGLRVLTDETAGLARLIVKLQGCELNHQVAALAIDALGELGVLYHEGPHLRAKGSWQRNYMFDLGLIIGGGTAQIQKNIIAERGLGLPREPKTVGA
>NC_011144.1|WP_012523047.1|2865489_2866827_+|sorbosone-dehydrogenase-family-protein
MRRHARVALPSLALALLALAACSTGSGEPWAGYGPDPHLPKPQKSLIPVVNVAEVKGWAAGEAPTAPPGFVVTRFGEGFDHPRWLLPLPNGDVLVAESSSESKPPKGIRGFFQNLIMKRAGAQEKSPDRIMLLRDADGDGVAEVKTIFAQNIRRPFGMALVGESLYVARDDGVVRFPYAPGQTRVEGAGETVFALPAGRNHHWTKSLIASPDGTKLYATVGSNSNVAENGMEEEVGRAAIHEYDIATGKLRLFASGLRNPNGLGWEPATGALWTTVNERDEIGNDLVPDYMTSVRDGGFYGWPYSYYGQNVDARVKPPRPDLVATAIKPDYALGPHTASLGLTFYTADAFPPAYRGGAFVGQHGSWNRRPLNGYQVVFVPFRGGRPQTPPQAFLTGFLDEDGKVRGRPVGVAVDGGGALLVADDVGEIVWRVAPAAPPAAQVSPS

You can click texts colored in the table to view more detailed information

Click the colored protein region to show detailed information

Crispr_ID: NC_011144_5

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_011144_5

3679716-3679896

Orphan

Consensus_repeat	Method
GACCACCGGCACGATGGGCGACACC	CRISPRCasFinder

3 spacers

The CRISPR arrays of NC_011144_5

>merge|NC_011144|5|3679716-3679896|CRISPRCasFinder
GACCACCGGCACGATGGGCGACACCGGCGCCATGGCTCCCGCTCCGGCCCCGGGGACGATGGGCGACACGACCGGGACGACCGGCACGATGGGCGACACCACGGGAACGATGGGCGCGACGACCCCGCCCCCCACCACGACCCCGCCGCCGACCGACGGCACGGGCACGACCGGCTCCACC

>NC_011144|5|4|3679716-3679896|CRISPRCasFinder
GACCACCGGCACGATGGGCGACACC	GGCGCCATGGCTCCCGCTCC
GGCCCCGGGGACGATGGGCGACACG	ACCGGGACGACCGGCACGATGGGCGA
CACCACGGGAACGATGGGCGCGACG	ACCCCGCCCCCCACCACGACCCCGCCGCCGACCGA
CGGCACGGGCACGACCGGCTCCACC

Protein	Signature genes	Signature genes Name	Protein_function
NC_011144.1\|WP_148217003.1\|3670162_3671194_-\|chemotaxis-specific-protein-glutamate-methyltransferase-CheB	unknown	unknown	gnl\|CDD\|234828
NC_011144.1\|WP_012523788.1\|3674041_3674875_-\|FkbM-family-methyltransferase	unknown	unknown	gnl\|CDD\|273628
NC_011144.1\|WP_041373685.1\|3683168_3683429_-\|hypothetical-protein	unknown	unknown	unknown
NC_011144.1\|WP_012523795.1\|3681219_3682386_+\|acyl-CoA-dehydrogenase-family-protein	unknown	unknown	gnl\|CDD\|173847
NC_011144.1\|WP_086004019.1\|3689128_3691018_+\|glycoside-hydrolase-family-15-protein	unknown	unknown	gnl\|CDD\|225922
NC_011144.1\|WP_012523801.1\|3687561_3688974_-\|pyruvate-kinase	unknown	unknown	gnl\|CDD\|180487
NC_011144.1\|WP_012523792.1\|3677833_3679027_+\|thiolase-domain-containing-protein	unknown	unknown	gnl\|CDD\|236164
NC_011144.1\|WP_148216908.1\|3679924_3681175_-\|CoA-transferase	unknown	unknown	gnl\|CDD\|367110
NC_011144.1\|WP_012523800.1\|3686868_3687525_-\|6-phosphogluconolactonase	unknown	unknown	gnl\|CDD\|238694
NC_011144.1\|WP_012523796.1\|3682382_3683165_+\|enoyl-CoA-hydratase/isomerase-family-protein	unknown	unknown	gnl\|CDD\|223955
NC_011144.1\|WP_083770993.1\|3674918_3675614_-\|glycosyltransferase	unknown	unknown	gnl\|CDD\|340837
NC_011144.1\|WP_148217004.1\|3672470_3674066_+\|response-regulator	unknown	unknown	gnl\|CDD\|274362
NC_011144.1\|WP_049758329.1\|3671729_3672320_+\|BLUF-domain-containing-protein	unknown	unknown	gnl\|CDD\|377423
NC_011144.1\|WP_012523797.1\|3683431_3684067_-\|bifunctional-4-hydroxy-2-oxoglutarate-aldolase/2-dehydro-3-deoxy-phosphogluconate-aldolase	unknown	unknown	gnl\|CDD\|235577
NC_011144.1\|WP_012523798.1\|3684063_3685035_-\|glucokinase	unknown	unknown	gnl\|CDD\|367143
NC_011144.1\|WP_049758331.1\|3676780_3677203_-\|PaaI-family-thioesterase	unknown	unknown	gnl\|CDD\|239527
NC_011144.1\|WP_012523799.1\|3685034_3686849_-\|phosphogluconate-dehydratase	unknown	unknown	gnl\|CDD\|181628
NC_011144.1\|WP_041373683.1\|3677199_3677664_-\|PaaI-family-thioesterase	unknown	unknown	gnl\|CDD\|239527
NC_011144.1\|WP_012523784.1\|3669332_3670166_-\|protein-glutamate-O-methyltransferase-CheR	unknown	unknown	gnl\|CDD\|224271
NC_011144.1\|WP_041373684.1\|3679029_3679431_+\|Zn-ribbon-domain-containing-OB-fold-protein	unknown	unknown	gnl\|CDD\|224462

Protein	Function_ID	Function_description	E-value
NC_011144.1\|WP_148217003.1\|3670162_3671194_-\|chemotaxis-specific-protein-glutamate-methyltransferase-CheB	gnl\|CDD\|234828	PRK00742, PRK00742, chemotaxis-specific protein-glutamate methyltransferase CheB.	2.56035e-148
NC_011144.1\|WP_012523788.1\|3674041_3674875_-\|FkbM-family-methyltransferase	gnl\|CDD\|273628	TIGR01444, 2-O-methyltransferase_NoeI, methyltransferase, FkbM family. Members of this family are characterized by two well-conserved short regions separated by a variable in both sequence and length. The first of the two regions is found in a large number of proteins outside this subfamily, a number of which have been characterized as methyltransferases. One member of the present family, FkbM, was shown to be required for a specific methylation in the biosynthesis of the immunosuppressant FK506 in Streptomyces strain MA6548.	2.96629e-30
NC_011144.1\|WP_012523797.1\|3683431_3684067_-\|bifunctional-4-hydroxy-2-oxoglutarate-aldolase/2-dehydro-3-deoxy-phosphogluconate-aldolase	gnl\|CDD\|235577	PRK05718, PRK05718, keto-hydroxyglutarate-aldolase/keto-deoxy-phosphogluconate aldolase; Provisional.	3.10073e-90
NC_011144.1\|WP_012523795.1\|3681219_3682386_+\|acyl-CoA-dehydrogenase-family-protein	gnl\|CDD\|173847	cd01158, SCAD_SBCAD, Short chain acyl-CoA dehydrogenases and eukaryotic short/branched chain acyl-CoA dehydrogenases. Short chain acyl-CoA dehydrogenase (SCAD). SCAD is a mitochondrial beta-oxidation enzyme. It catalyzes the alpha,beta dehydrogenation of the corresponding trans-enoyl-CoA by FAD, which becomes reduced. The reduced form of SCAD is reoxidized in the oxidative half-reaction by electron-transferring flavoprotein (ETF), from which the electrons are transferred to the mitochondrial respiratory chain coupled with ATP synthesis. This subgroup also contains the eukaryotic short/branched chain acyl-CoA dehydrogenase(SBCAD), the bacterial butyryl-CoA dehydorgenase(BCAD) and 2-methylbutyryl-CoA dehydrogenase, which is involved in isoleucine catabolism. These enzymes are homotetramers.	5.22576e-99
NC_011144.1\|WP_086004019.1\|3689128_3691018_+\|glycoside-hydrolase-family-15-protein	gnl\|CDD\|225922	COG3387, SGA1, Glucoamylase and related glycosyl hydrolases [Carbohydrate transport and metabolism].	7.85506e-73
NC_011144.1\|WP_012523801.1\|3687561_3688974_-\|pyruvate-kinase	gnl\|CDD\|180487	PRK06247, PRK06247, pyruvate kinase; Provisional.	0
NC_011144.1\|WP_012523792.1\|3677833_3679027_+\|thiolase-domain-containing-protein	gnl\|CDD\|236164	PRK08142, PRK08142, thiolase domain-containing protein.	0
NC_011144.1\|WP_148216908.1\|3679924_3681175_-\|CoA-transferase	gnl\|CDD\|367110	pfam02515, CoA_transf_3, CoA-transferase family III. CoA-transferases are found in organisms from all lines of descent. Most of these enzymes belong to two well-known enzyme families, but recent work on unusual biochemical pathways of anaerobic bacteria has revealed the existence of a third family of CoA-transferases. The members of this enzyme family differ in sequence and reaction mechanism from CoA-transferases of the other families. Currently known enzymes of the new family are a formyl-CoA: oxalate CoA-transferase, a succinyl-CoA: (R)-benzylsuccinate CoA-transferase, an (E)-cinnamoyl-CoA: (R)-phenyllactate CoA-transferase, and a butyrobetainyl-CoA: (R)-carnitine CoA-transferase. In addition, a large number of proteins of unknown or differently annotated function from Bacteria, Archaea and Eukarya apparently belong to this enzyme family. Properties and reaction mechanisms of the CoA-transferases of family III are described and compared to those of the previously known CoA-transferases.	2.37233e-117
NC_011144.1\|WP_012523800.1\|3686868_3687525_-\|6-phosphogluconolactonase	gnl\|CDD\|238694	cd01400, 6PGL, 6PGL: 6-Phosphogluconolactonase (6PGL) subfamily; 6PGL catalyzes the second step of the oxidative phase of the pentose phosphate pathway, the hydrolyzation of 6-phosphoglucono-1,5-lactone (delta form) to 6-phosphogluconate. 6PGL is thought to guard against the accumulation of the delta form of the lactone, which may be toxic through its reaction with endogenous cellular nucleophiles.	5.30111e-61
NC_011144.1\|WP_012523796.1\|3682382_3683165_+\|enoyl-CoA-hydratase/isomerase-family-protein	gnl\|CDD\|223955	COG1024, CaiD, Enoyl-CoA hydratase/carnithine racemase [Lipid metabolism].	2.87349e-60
NC_011144.1\|WP_083770993.1\|3674918_3675614_-\|glycosyltransferase	gnl\|CDD\|340837	cd03808, GT4_CapM-like, capsular polysaccharide biosynthesis glycosyltransferase CapM and similar proteins. This family is most closely related to the GT4 family of glycosyltransferases. CapM in Staphylococcus aureus is required for the synthesis of type 1 capsular polysaccharides.	5.83073e-13
NC_011144.1\|WP_148217004.1\|3672470_3674066_+\|response-regulator	gnl\|CDD\|274362	TIGR02956, sensor_protein_TorS, TMAO reductase sytem sensor TorS. This protein, TorS, is part of a regulatory system for the torCAD operon that encodes the pterin molybdenum cofactor-containing enzyme trimethylamine-N-oxide (TMAO) reductase (TorA), a cognate chaperone (TorD), and a penta-haem cytochrome (TorC). TorS works together with the inducer-binding protein TorT and the response regulator TorR. TorS contains histidine kinase ATPase (pfam02518), HAMP (pfam00672), phosphoacceptor (pfam00512), and phosphotransfer (pfam01627) domains and a response regulator receiver domain (pfam00072). [Signal transduction, Two-component systems].	1.34449e-96
NC_011144.1\|WP_049758329.1\|3671729_3672320_+\|BLUF-domain-containing-protein	gnl\|CDD\|377423	pfam04940, BLUF, Sensors of blue-light using FAD. The BLUF domain has been shown to bind FAD in the AppA protein. AppA is involved in the repression of photosynthesis genes in response to blue-light.	1.75821e-35
NC_011144.1\|WP_012523798.1\|3684063_3685035_-\|glucokinase	gnl\|CDD\|367143	pfam02685, Glucokinase, Glucokinase. This is a family of glucokinases or glucose kinases EC:2.7.1.2. These enzymes phosphorylate glucose using ATP as a donor to give glucose-6-phosphate and ADP.	1.08702e-124
NC_011144.1\|WP_049758331.1\|3676780_3677203_-\|PaaI-family-thioesterase	gnl\|CDD\|239527	cd03443, PaaI_thioesterase, PaaI_thioesterase is a tetrameric acyl-CoA thioesterase with a hot dog fold and one of several proteins responsible for phenylacetic acid (PA) degradation in bacteria. Although orthologs of PaaI exist in archaea and eukaryotes, their function has not been determined. Sequence similarity between PaaI, E. coli medium chain acyl-CoA thioesterase II, and human thioesterase III suggests they all belong to the same thioesterase superfamily. The conserved fold present in these thioesterases is referred to as an asymmetric hot dog fold, similar to those of 4-hydroxybenzoyl-CoA thioesterase (4HBT) and the beta-hydroxydecanoyl-ACP dehydratases (FabA/FabZ).	3.05012e-28
NC_011144.1\|WP_012523799.1\|3685034_3686849_-\|phosphogluconate-dehydratase	gnl\|CDD\|181628	PRK09054, PRK09054, phosphogluconate dehydratase; Validated.	0
NC_011144.1\|WP_041373683.1\|3677199_3677664_-\|PaaI-family-thioesterase	gnl\|CDD\|239527	cd03443, PaaI_thioesterase, PaaI_thioesterase is a tetrameric acyl-CoA thioesterase with a hot dog fold and one of several proteins responsible for phenylacetic acid (PA) degradation in bacteria. Although orthologs of PaaI exist in archaea and eukaryotes, their function has not been determined. Sequence similarity between PaaI, E. coli medium chain acyl-CoA thioesterase II, and human thioesterase III suggests they all belong to the same thioesterase superfamily. The conserved fold present in these thioesterases is referred to as an asymmetric hot dog fold, similar to those of 4-hydroxybenzoyl-CoA thioesterase (4HBT) and the beta-hydroxydecanoyl-ACP dehydratases (FabA/FabZ).	4.3568e-28
NC_011144.1\|WP_012523784.1\|3669332_3670166_-\|protein-glutamate-O-methyltransferase-CheR	gnl\|CDD\|224271	COG1352, CheR, Methylase of chemotaxis methyl-accepting proteins [Cell motility and secretion / Signal transduction mechanisms].	4.71098e-91
NC_011144.1\|WP_041373684.1\|3679029_3679431_+\|Zn-ribbon-domain-containing-OB-fold-protein	gnl\|CDD\|224462	COG1545, COG1545, Predicted nucleic-acid-binding protein containing a Zn-ribbon [General function prediction only].	1.47495e-24

>NC_011144.1|WP_041373684.1|3679029_3679431_+|Zn-ribbon-domain-containing-OB-fold-protein
MSEVMSRPIPAPPVTVESKPFWDAASEGRFLIKRCTACAKAHWYPRTICPFCASDATVWEESPGEGEVYSFSIMRRSPTGPYALAYVTLNEGPRVLTNIVDVTPEDLRIGMRVKVRFQETEGEGPPAPVFAPA
>NC_011144.1|WP_012523792.1|3677833_3679027_+|thiolase-domain-containing-protein
MSIRGQAYVMGAFEHPTRDAPEKTTAQLHAESARGALADAGLSFADVDGYFCAGDAPGFGGLSMVDYMGLRNVRHLDSTEMGGSSYIAHVGHAAQAIAAGKCRVALITLAGRPRNGGNRPGASMRPGGGGTGLSDGPPEAGFEHIYGGSTHNTYGMAAMRHMHEYGTTSEQLAWIKVAASHHAQWNEHAFLKNVVTVEEVVNSRMISDPLHLLDCCVVTDGGGALVVTSPEIAKSLNRPKVRVLGAGEAPKGQMGGDLDLTYSGAVWSGPRAFEEAGVTPADIKYASIYDSFTITVLIQLEDLGFCAKGEGGRFVADGNLISGVGKLPFNTDGGGLCNNHPTNRGGMTKVIEAVRQLRGEAHPKVQAPNCDLAIAHGTGGSLGIRHGSATVILEREA
>NC_011144.1|WP_041373683.1|3677199_3677664_-|PaaI-family-thioesterase
MSETAEPGFATIRERIHAGLNGQGMLHHLDVRIDEVAPGRVVLSLPFRKEVAQQNGFFHGGAIGFLVDDATAAAAATVVRDGETVLTAEYKINFVAPGVGERLVCRAETIKAGRTLIPVEARVYAVKDGVETLCAVALASMAVRAFDRLKGGQA
>NC_011144.1|WP_049758331.1|3676780_3677203_-|PaaI-family-thioesterase
MMDGDLAAQFAERQKGTLPGELGLEWEEVANGRARGRFTVRKGHTAPNGFLHAASVIALGDSACGYACMASAPEGASGFTTIELKANYLATAKEGEVVSCEARLVHGGRMTQVWDAEARNETTGKTMALFRCTQMILYPK
>NC_011144.1|WP_083770993.1|3674918_3675614_-|glycosyltransferase
MATGLPVVASDWDGYRDTVRDGVDGFLVPTWAPSPGLGNHLAFAHQGRTITDDMLSWGAAAATSVDAERLVAALAELIASPGLRRRMGAAGQAHARAIFDWSHVYAAYGSLWAELDARRRTEGGDVQTPRSGGQLEPFTAFASYPTRAISGETTIALRPEADPAAYRVLAGHALYPGGAAAAGAVAPLWGLLEQGPLTAAAAAEALGRPLRSVVNAAGVLAKMGFVTLGPG
>NC_011144.1|WP_012523788.1|3674041_3674875_-|FkbM-family-methyltransferase
MLDSTIAYGLTFLVPAGDRAIGLSLRLYGEFARPEVDFLLACAGEPGVFIDVGANVGAISLPFARRRPDWRVISIEAHRGLAGLLTANALNNQLYNVEAIHAAAGPKEGLARFPAPPLDASLNFGGVGFGFDAPKETVRMLTLDDLAPPETRLVKIDVEGFEAQVLDGAGGLIESRRAIWLIEAAGRDREARASTIGRFQAAGYDVHWFYAPFATPASPKGKPGNPVVGDVNVVATPPGVTPPWPLQRVQDPGEPAPPSVAGYDYLLSYGYAPLTPG
>NC_011144.1|WP_148217004.1|3672470_3674066_+|response-regulator
MGAALRRALAARAGLNDNLEDVLNGILNISSEGIVVLDARLRILVFSPGAEAAFGWSADEMVGQSIERLIPPALRASHRKHVEAFAAGEAQSRRMSDRSDIFGLRRNGEVFPLEVGLSKLMTSKGQIYTALLRDVSDRREAEQALALAAAEAQAANQAKSAFLAAMSHEIRTPLNGVLGMAQAMAMEDLPPHQRERLEVIRQSGESLLAILNDLLDLSKIEAGKLELEDAEFDIQELARGAHATFVAVAEARGLAFEVAVAPAARGVYRGDPLRVRQILHNLISNALKFTEAGSVRVTVGRSGGALSLVVQDTGIGIPPEKAARLFQKFEQADASTTRRFGGTGLGLAICRDLAQMMGGSIGVESAPGEGATFTVLLPLKRIARAPAPPTAAPPPPTPRETALKVLVAEDNAVNQVVLKTLLEQLGVAATVAPDGRAAVAAWEREPWDVILMDVQMPEMDGPTATGVIRRREAAEGRPRTPIVGLTANAMQHQIAEYRNAGMDDVVAKPVQVDRLVEALNAAAAQPGVSGA
>NC_011144.1|WP_049758329.1|3671729_3672320_+|BLUF-domain-containing-protein
MFFEGSADGGVGVCRPAVGGHGLRPPPATLVAPARRTDERPAPALQRLIYASAATPETAADMAGVLDDILQAGRACNAALGVTGALLVCDGWFLQLLEGPKESVRQVYGAVSSDRRHTDLRLIENRPAAVRQFGDWSLCCGVFRPDDEAFAGEPAMRDGFRPETLTPASSLGLLSILRDLQHGAGAGGLDSARPAA
>NC_011144.1|WP_148217003.1|3670162_3671194_-|chemotaxis-specific-protein-glutamate-methyltransferase-CheB
MVVDDSAVVRGLITRQLESDSRLEVVCTASNGELALRELARHPVDVVVLDIEMPVMDGLTALQRIVAEHPGVRVIMASTLTLRNAEISLKALQLGASDYVAKPENGLAGAQEFQRELTSKILALAPRRARPAPAPASPAARRPIVPALRRTLPQVLAIGASTGGPPALLQVFEALKGAVRLPILLTQHMPATFTALLAEQIGRAGDRPCAEARDGEPVVPGRCYVAPGGWHMTVEREGAGVFIRLNQEPPENFCRPAVDPMLRSVAQAYGPAALAVILTGMGSDGAKGCEAIAAAGGRFIVQDEATSVVWGMPGAAAATGRAEGVLPLSEVGGWIRRATEVAA
>NC_011144.1|WP_012523784.1|3669332_3670166_-|protein-glutamate-O-methyltransferase-CheR
MTGPDFEHFCQLIRARSGLVLTPEKAYLVNSRLGPVARAEGLAGVPELLARLRAGAPEPLIQRCVEAMATHESFFFRDGAPFEQLANRLLPELIEARRAVRTLRIWCAACSSGQEPYSVAMVLQEAGAQLGGWRLEIVATDMSEPILSKARSGLYSDFEVNRGLSEERLKRWFTREGGSWRIAPQLKQMVSFRTHNLLHGVGGLGMFDVIFCRNVLIYFDVAQKRTILAELARSLAPDGALFLGSAETVIGITDAFTLSPAARGLYLPSSARLARSA
>NC_011144.1|WP_148216908.1|3679924_3681175_-|CoA-transferase
MRRSQGRRNVGEAKRLADKATGPLAGIRVLDLTSVVNGAYGTQILADQGADVIKLEDPGSGRGDGGDIMRWAGHTPEGCPRDMGPIFLTINRNKRSILLDLKQESARRALRRLIRTCDVFATSIRYEGLKRLGLAYEDVAQVRPDIVYAHAAGYGSDGPYAGEPAYDDLIQSASGMADILPRTDGNPVPRILPTLIADKVSGLFFAQSVTAALLHRQRTGEGQFVEVPMYECVTSFLLVEHLYDRAYEPPTGQWGYQRVINPNRKPFRTKDGYIGLLPYTDRQWDQFFDAAGFGEAVKSDPRFADYATRAKHTRELYGLIEQAAATKTTQEWLDILKPLSIPVVKTNTFEDLDADPHLQAVDFFQTYEHAEVGRYRMIKPPVKFSKSPANIRRHAPRLGEHTEEVLAEVSDPAKAG
>NC_011144.1|WP_012523795.1|3681219_3682386_+|acyl-CoA-dehydrogenase-family-protein
MDFELSEEHRMLKDLVARFVRDELTPLEAGVMAREAEGKGAYLAPEEHARLDEVSRRLGLWGLDAPEDVGGSDLPMVAMVGVEEELGRTVTPYTLPPDSPNLRMLMATVDERQRAAYLAPYVAGKTVSAIGISEPGAGSDPAAMTTRAVRDGDDWVIDGRKIWISRADHADFTILMAVTDKEKGARGGVSAFLVDKGTPGFNVLRRIPMLGGQYTYEIALEGCRVEGWKLLGQEGAGFAPMQTRLGTRRIQMAAWSVGMAQRALDMVVDYAPQRKTFGVPLSERQAIQWWVAEAATKIHAARLMTYDCAWKLDQGRDVRSEISMIKWYATEMAYETVDRAMQAFGAMGMTKELPLQLMQAKLRTMRIYDGPTEVHKWVVARNLLGTRR
>NC_011144.1|WP_012523796.1|3682382_3683165_+|enoyl-CoA-hydratase/isomerase-family-protein
MKSAFGDHVTVAMDGHVAVVTLDRAPHNFVSVEFMRDLADAMDAIDNNDTARAIVLQTEGRTFCGGADFSSPDDKVASGMDGVQALYAQAVRLFSVETPIVAAVQGAAVGAGLGLALTADFRVAAPEARFVANFVKLAFHPGFGLTHTLPRVIGQQRASLMFLTGRRIKAEEALAWGLVDELVPAEEVRAAALRLAHEIAENAPLAVVSTRKTLRADLAAAVKAQTAHEHQEQALLRQTEDFKEGVRAVAERRPGNWVGR
>NC_011144.1|WP_041373685.1|3683168_3683429_-|hypothetical-protein
MADRANEQLRWVVTARARPGEPGSAVVSVLGRNAMIPELAFDMAVDWHPGAEAADVEGRALVILSLLFKELAAECERAAGERFNLG
>NC_011144.1|WP_012523797.1|3683431_3684067_-|bifunctional-4-hydroxy-2-oxoglutarate-aldolase/2-dehydro-3-deoxy-phosphogluconate-aldolase
MTLPDILTRAPVIPVLVVDDVAHAVPLGRALVAGGLPVLEVTLRTPVALDCIRAMSGIEGAIVGAGTVLNRQMRRAAAEAGAKFVVSPGLIEGEGPDGPAPLLPGVATATELMAGLAAGFTHFKLFPANIVGGVDALKAYQSPFQQAKFCPTGGVGAKNAAEYLALPNVICVGGSWVAPADAVRAGDWDRITALAREAAALAPRAPAPVEG
>NC_011144.1|WP_012523798.1|3684063_3685035_-|glucokinase
MKPQYAGLVGDVGGTHARFALVDVEGRIRNPRTFESREYGSLTDIVAEYIQTTAGKRRPPRAVIAVAGPVLDGEIEFTNLDWHVTEGDLLAHFEFEAVKLINDFAAQALACPRLDAGDLRAIGPDLGRGAYDCPVVVLGAGTGFGVAGVARSERGDVAVATEGGHAAFAPTDEIEVELWRRLKARYGRVSIERLLSGQGLFDIYQGLADIEGRPAPLADPPAVMTEGLAGDPLAGAALDRFAGILGSVAGDLALSFGARGGVYVSGGIAPRMADRLAAGPFRARFEDKGRLSDYVRGVPTYLVLHPYPAIVGAARELEQMERL
>NC_011144.1|WP_012523799.1|3685034_3686849_-|phosphogluconate-dehydratase
MLHPVTAEVTQRIVERSRESRADYLARMEAARGQSPGRGKLSCANWAHAFAASPEGDKQRMRDPAAPNVAIVSAYNDMLSAHQPYERFPAIIKHAAREAGATAQYAGGVPAMCDGVTQGRPGMELSLFSRDVIAMSTAVALTHDAFDAALMLGICDKIVPGLFIGAAAFGHLPVIFVPGGPMTSGISNSEKARVRALYAEGKATRDELLDSEMKSYHGPGTCTFYGTANSNQMMMELSGLHLPGAAFVTPNTPLRDALTAAAPRRALEIRDGTNGYAPFSAVVDEKSLVNAIAGLLATGGSTNHTLHILAMARAAGVRITWEDMDDLSRVTPLIARVYPNGTEDVNAFHAAGGMAFVTRQLLDAGLAHEDVMTVAGPGLRRYQQEPFLDGGRLVWREGPAATLDRDILRPADDPFQAEGGLRLLTGPLGRGVIKTSAVKPEHRIVEAPALVFDDQEALLAAHRRGELNRDFVAVVRFQGPRANGMPELHSLTPALGVQLDKGFKVALVTDGRMSGASGKVPAAIHMTPEAADGGPLARVRDGDVIRLDAEAGRLEIKVEVKELMAREPATGRSSEVGYGRELFGWMRRAAGPADTGACALFEAA
>NC_011144.1|WP_012523800.1|3686868_3687525_-|6-phosphogluconolactonase
MLETYSSADALGEACAHAVAACLSEALKTRGRAGLVATGGRSPGPVYDRLAKARLDWARVVVTLSDERCVEASSPDSNARQVRERLLVGEAAKAHLLPLWPRPDPAAIRALLPFDAVLLGMGEDGHVASLIPGDPGLAHALSTKEHLVDVPEGLGKPPTARVSLTMSALTQARSVFLLIAGDAKREVIRRAQAGEDLPVGRLLAGSAAPVRIFWSPTH
>NC_011144.1|WP_012523801.1|3687561_3688974_-|pyruvate-kinase
MIRARRARIVATLGPASRDLDKVRELALAGADVFRVNFSHGTHADHARTIQNVRKAEQAVGRPIAVLADLQGPKLRLGRFAERSAPLKAGQRFRIDMDKTPGDSERVGVPHPEVFAAIREGAVVLLDDGKVRLRVVKHGPDWADTVVEAGEQLSDHKGLNLPGSAIPIPALTEKDRKDLAFALQEGVDWVALSFVQRASDMAELRQIVAGRAGVLAKIEKPAALNALDEILDLSEAVMVARGDLGVELAPEEVPVAQKQLIRAARMRGIPVIVATQMLESMIHSPTPTRAEASDVAGAVYEGADAVMLSAETAAGDYPLEAVSIMDRIITRVEQDPRWSELMRAQHEVGDADALVSAAFHAAETASAACVAAFTLTGQTALRLGRERPVQPTLALTPRLATARRLALAWGVEARVVADIRDPEDIPKLACHEAMAAGLAGPAQRILILAGLPMGAPGAANILRLAHTPRR
>NC_011144.1|WP_086004019.1|3689128_3691018_+|glycoside-hydrolase-family-15-protein
MSQTLDLFPIGNCAASALIDRTGRYIWACVPRVDGDPVFCALLDGRDPAAEKAQGLWAIDVEGAAEITQAYLRNTPILRTEIRTADGAAVEIIDFCPRYRHLGRQYRPMAFVRIVRPLAGAPRIRVRLSPMMNYGERACYQTAGSNHIRFVGEVMTLRLTTDCPVSHVQEARTFRLEEPLGFFLGPDEGLDADVATVTERMLRETTEYWRRWVRTLSVPLQWQEAVIRAAITLKLCTYEETGAIVAALTTSVPEHAADDGAGRNWDYRYCWLRDAYYVVQALNRLGAADILENYLGYLRNIVDQAGRGSIEGGPNGNGQPALPGLGPCGVDRGRAGHVQPVYGVGMEPVLTEWIAPHLRGYRGIGPVRVGNQAHEHMQHDVYGQIILSTVQAFFDERLLRPATVDDFCALEPIAERAFELHDKPDASLWEFRGREAVHTYSSVMCWAACDRLGNAAVKLGLTERAAYWNDRAARIRATIEARAWNEAEGRFAATFDGDELDASLLQLVDVRFASPDDPRMQATMAAVEHGLRRGPFMLRYAIADDFGVPKTAFNFCTFWLIEALHLSGRSDEARALFEEMLERRTAAGLLSEDISFTGDELWGNYPQTYSLVGLINCAMLLSEPWSSVR

You can click texts colored in the table to view more detailed information

Click the colored protein region to show detailed information

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Identity
NC_011144_3	3.3\|2030864\|16\|NC_011144\|CRISPRCasFinder	2030864-2030879	16	NC_011144.1	1780693-1780708	1.0
NC_011144_3	3.4\|2030906\|16\|NC_011144\|CRISPRCasFinder	2030906-2030921	16	NC_011143.1	312524-312539	1.0
NC_011144_3	3.4\|2030906\|16\|NC_011144\|CRISPRCasFinder	2030906-2030921	16	NC_011144.1	1832048-1832063	1.0
NC_011144_3	3.4\|2030906\|16\|NC_011144\|CRISPRCasFinder	2030906-2030921	16	NC_011144.1	2336236-2336251	1.0
NC_011144_3	3.4\|2030906\|16\|NC_011144\|CRISPRCasFinder	2030906-2030921	16	NC_011144.1	2363452-2363467	1.0
NC_011144_3	3.5\|2030948\|16\|NC_011144\|CRISPRCasFinder	2030948-2030963	16	NC_011144.1	155205-155220	1.0
NC_011144_3	3.5\|2030948\|16\|NC_011144\|CRISPRCasFinder	2030948-2030963	16	NC_011144.1	925619-925634	1.0
NC_011144_3	3.5\|2030948\|16\|NC_011144\|CRISPRCasFinder	2030948-2030963	16	NC_011144.1	1108017-1108032	1.0

1. spacer 3.3|2030864|16|NC_011144|CRISPRCasFinder matches to position: 1780693-1780708, mismatch: 0, identity: 1.0

gccgccgaagcccccg	CRISPR spacer
gccgccgaagcccccg	Protospacer
****************

2. spacer 3.4|2030906|16|NC_011144|CRISPRCasFinder matches to position: 312524-312539, mismatch: 0, identity: 1.0

gaagcccgcgccgccg	CRISPR spacer
gaagcccgcgccgccg	Protospacer
****************

3. spacer 3.4|2030906|16|NC_011144|CRISPRCasFinder matches to position: 1832048-1832063, mismatch: 0, identity: 1.0

gaagcccgcgccgccg	CRISPR spacer
gaagcccgcgccgccg	Protospacer
****************

4. spacer 3.4|2030906|16|NC_011144|CRISPRCasFinder matches to position: 2336236-2336251, mismatch: 0, identity: 1.0

gaagcccgcgccgccg	CRISPR spacer
gaagcccgcgccgccg	Protospacer
****************

5. spacer 3.4|2030906|16|NC_011144|CRISPRCasFinder matches to position: 2363452-2363467, mismatch: 0, identity: 1.0

gaagcccgcgccgccg	CRISPR spacer
gaagcccgcgccgccg	Protospacer
****************

6. spacer 3.5|2030948|16|NC_011144|CRISPRCasFinder matches to position: 155205-155220, mismatch: 0, identity: 1.0

gccgtcgccggccagg	CRISPR spacer
gccgtcgccggccagg	Protospacer
****************

7. spacer 3.5|2030948|16|NC_011144|CRISPRCasFinder matches to position: 925619-925634, mismatch: 0, identity: 1.0

gccgtcgccggccagg	CRISPR spacer
gccgtcgccggccagg	Protospacer
****************

8. spacer 3.5|2030948|16|NC_011144|CRISPRCasFinder matches to position: 1108017-1108032, mismatch: 0, identity: 1.0

gccgtcgccggccagg	CRISPR spacer
gccgtcgccggccagg	Protospacer
****************

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NC_011144_3	3.7\|2031056\|22\|NC_011144\|CRISPRCasFinder	2031056-2031077	22	NZ_CP041156	Leisingera aquaemixtae strain R2C4 plasmid unnamed1, complete sequence	82121-82142	2	0.909
NC_011144_3	3.7\|2031056\|22\|NC_011144\|CRISPRCasFinder	2031056-2031077	22	NZ_CP022565	Rhizobium leguminosarum bv. viciae strain BIHB 1148 plasmid pSK01, complete sequence	266558-266579	2	0.909
NC_011144_3	3.7\|2031056\|22\|NC_011144\|CRISPRCasFinder	2031056-2031077	22	NZ_CP048281	Rhizobium leguminosarum bv. viciae 248 plasmid pRle248e, complete sequence	314265-314286	3	0.864
NC_011144_5	5.2\|3679786\|26\|NC_011144\|CRISPRCasFinder	3679786-3679811	26	NZ_CP022192	Yangia pacifica strain YSBP01 plasmid unnamed2, complete sequence	126381-126406	5	0.808
NC_011144_5	5.2\|3679786\|26\|NC_011144\|CRISPRCasFinder	3679786-3679811	26	NZ_CP049906	Diaphorobacter sp. HDW4B plasmid unnamed1, complete sequence	72804-72829	5	0.808
NC_011144_3	3.1\|2030756\|37\|NC_011144\|CRISPRCasFinder	2030756-2030792	37	NC_020062	Rhizobium tropici CIAT 899 plasmid pRtrCIAT899c, complete sequence	1600782-1600818	8	0.784
NC_011144_5	5.3\|3679837\|35\|NC_011144\|CRISPRCasFinder	3679837-3679871	35	NZ_CP022369	Azospirillum sp. TSH58 plasmid TSH58_p05, complete sequence	274214-274248	10	0.714
NC_011144_5	5.3\|3679837\|35\|NC_011144\|CRISPRCasFinder	3679837-3679871	35	NZ_CP032348	Azospirillum brasilense strain MTCC4039 plasmid p4, complete sequence	89178-89212	10	0.714
NC_011144_5	5.3\|3679837\|35\|NC_011144\|CRISPRCasFinder	3679837-3679871	35	NZ_CP032349	Azospirillum brasilense strain MTCC4039 plasmid p3, complete sequence	308346-308380	10	0.714
NC_011144_3	3.6\|2030990\|40\|NC_011144\|CRISPRCasFinder	2030990-2031029	40	AP018462	Mycobacterium phage D12 DNA, complete genome	22357-22396	11	0.725
NC_011144_3	3.6\|2030990\|40\|NC_011144\|CRISPRCasFinder	2030990-2031029	40	AP018463	Mycobacterium phage PR DNA, complete genome	22334-22373	11	0.725
NC_011144_5	5.3\|3679837\|35\|NC_011144\|CRISPRCasFinder	3679837-3679871	35	NZ_CP032325	Azospirillum brasilense strain MTCC4035 plasmid p4, complete sequence	17967-18001	11	0.686
NC_011144_3	3.6\|2030990\|40\|NC_011144\|CRISPRCasFinder	2030990-2031029	40	NZ_CP025013	Rhizobium leguminosarum strain Norway plasmid pRLN1, complete sequence	780022-780061	12	0.7

1. spacer 3.7|2031056|22|NC_011144|CRISPRCasFinder matches to NZ_CP041156 (Leisingera aquaemixtae strain R2C4 plasmid unnamed1, complete sequence) position: , mismatch: 2, identity: 0.909

gttggcgccgccgccggatccg	CRISPR spacer
ctgggcgccgccgccggatccg	Protospacer
 * *******************

2. spacer 3.7|2031056|22|NC_011144|CRISPRCasFinder matches to NZ_CP022565 (Rhizobium leguminosarum bv. viciae strain BIHB 1148 plasmid pSK01, complete sequence) position: , mismatch: 2, identity: 0.909

gttggcgccgccgccggatccg	CRISPR spacer
cttggcgccgccgccggatgcg	Protospacer
 ****************** **

3. spacer 3.7|2031056|22|NC_011144|CRISPRCasFinder matches to NZ_CP048281 (Rhizobium leguminosarum bv. viciae 248 plasmid pRle248e, complete sequence) position: , mismatch: 3, identity: 0.864

gttggcgccgccgccggatccg	CRISPR spacer
gttggcgccgccgccggatgaa	Protospacer
*******************  .

4. spacer 5.2|3679786|26|NC_011144|CRISPRCasFinder matches to NZ_CP022192 (Yangia pacifica strain YSBP01 plasmid unnamed2, complete sequence) position: , mismatch: 5, identity: 0.808

accgggacgaccggcacgatgggcga	CRISPR spacer
cccgggatgaccggcacgatggcggt	Protospacer
 ******.**************  *

5. spacer 5.2|3679786|26|NC_011144|CRISPRCasFinder matches to NZ_CP049906 (Diaphorobacter sp. HDW4B plasmid unnamed1, complete sequence) position: , mismatch: 5, identity: 0.808

accgggacgaccggcacgatgggcga	CRISPR spacer
gccgggacgaccaacacgatgggctc	Protospacer
.***********..**********

6. spacer 3.1|2030756|37|NC_011144|CRISPRCasFinder matches to NC_020062 (Rhizobium tropici CIAT 899 plasmid pRtrCIAT899c, complete sequence) position: , mismatch: 8, identity: 0.784

gcccagcc--cgccggccgaagtgttcgccgagcccgcg	CRISPR spacer
--atagccggcgccggccgaagcgatcgccgagcccggc	Protospacer
   .****  ************.* ************

7. spacer 5.3|3679837|35|NC_011144|CRISPRCasFinder matches to NZ_CP022369 (Azospirillum sp. TSH58 plasmid TSH58_p05, complete sequence) position: , mismatch: 10, identity: 0.714

accccgccccccaccacgaccccgccgccgaccga	CRISPR spacer
gcgccgccctccaccacgacctcgccgcgcgacag	Protospacer
.* ******.***********.******  . *..

8. spacer 5.3|3679837|35|NC_011144|CRISPRCasFinder matches to NZ_CP032348 (Azospirillum brasilense strain MTCC4039 plasmid p4, complete sequence) position: , mismatch: 10, identity: 0.714

accccgccccccaccacgaccccgccgccgaccga	CRISPR spacer
gtgcccttccccaccacgcccccgccgccgccctc	Protospacer
.. ** ..********** *********** **

9. spacer 5.3|3679837|35|NC_011144|CRISPRCasFinder matches to NZ_CP032349 (Azospirillum brasilense strain MTCC4039 plasmid p3, complete sequence) position: , mismatch: 10, identity: 0.714

accccgccccccaccacgaccccgccgccgaccga	CRISPR spacer
gcgccgccctccaccacgacctcgccgcgcgacag	Protospacer
.* ******.***********.******  . *..

10. spacer 3.6|2030990|40|NC_011144|CRISPRCasFinder matches to AP018462 (Mycobacterium phage D12 DNA, complete genome) position: , mismatch: 11, identity: 0.725

gccgccgccgaagtcgccgccgtcgccgccggggaaggtg	CRISPR spacer
agcgccgccgaggtcgccgccgtcgacgccgccaccgacg	Protospacer
. *********.************* *****  .  *..*

11. spacer 3.6|2030990|40|NC_011144|CRISPRCasFinder matches to AP018463 (Mycobacterium phage PR DNA, complete genome) position: , mismatch: 11, identity: 0.725

gccgccgccgaagtcgccgccgtcgccgccggggaaggtg	CRISPR spacer
agcgccgccgaggtcgccgccgtcgacgccgccaccgacg	Protospacer
. *********.************* *****  .  *..*

12. spacer 5.3|3679837|35|NC_011144|CRISPRCasFinder matches to NZ_CP032325 (Azospirillum brasilense strain MTCC4035 plasmid p4, complete sequence) position: , mismatch: 11, identity: 0.686

accccgccccccaccacgaccccgccgccgaccga	CRISPR spacer
gtgccgccctccaccacgacctcgccgcgcgacag	Protospacer
.. ******.***********.******  . *..

13. spacer 3.6|2030990|40|NC_011144|CRISPRCasFinder matches to NZ_CP025013 (Rhizobium leguminosarum strain Norway plasmid pRLN1, complete sequence) position: , mismatch: 12, identity: 0.7

gccgccgccgaagtcgccgccgtcgccgccggggaaggtg	CRISPR spacer
ctggccgcggaagacgccgccgtcgccgccggtctgcccg	Protospacer
 . ***** **** ******************   .  .*

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

1831087 : 1838789

Synechococcus_phage(33.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_012522178.1\|1831087_1832089_-	ADP-glyceromanno-heptose 6-epimerase	A0A1D8KKD9	Synechococcus_phage	3.8e-26	30.3
WP_012522179.1\|1832085_1833555_-	D-glycero-beta-D-manno-heptose 1-phosphate adenylyltransferase	E3SJ88	Synechococcus_phage	1.0e-19	44.4
WP_012522180.1\|1833589_1834447_-	3-deoxy-8-phosphooctulonate synthase	E3T537	Cafeteria_roenbergensis_virus	8.9e-48	42.7
WP_012522181.1\|1834620_1835832_+	class I SAM-dependent methyltransferase	A0A2K9L4K8	Tupanvirus	2.5e-35	29.8
WP_012522182.1\|1835878_1836880_+	cysteine synthase A	A0A1X9I5F1	Streptococcus_phage	1.8e-44	37.1
WP_012522183.1\|1836885_1837725_+	3-mercaptopyruvate sulfurtransferase	NA	NA	NA	NA
WP_049758404.1\|1837721_1838789_-	amino acid ABC transporter substrate-binding protein	A0A1B1IT51	uncultured_Mediterranean_phage	4.9e-72	42.6

DBSCAN-SWA_2

2187057 : 2199555

uncultured_Mediterranean_phage(90.0%)

tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_012522506.1\|2187057_2188020_-	protein translocase subunit SecF	A0A1B1IVP7	uncultured_Mediterranean_phage	1.0e-52	45.2
WP_012522507.1\|2188034_2189639_-	protein translocase subunit SecD	NA	NA	NA	NA
WP_012522508.1\|2189657_2190008_-	preprotein translocase subunit YajC	A0A1B1IVR5	uncultured_Mediterranean_phage	4.2e-12	51.8
WP_012522509.1\|2190125_2190965_+	ATP-binding protein	NA	NA	NA	NA
WP_012522510.1\|2190971_2192378_-	peptidoglycan DD-metalloendopeptidase family protein	M1HNA7	Bacillus_virus	2.1e-06	43.4
WP_012522511.1\|2192489_2193161_-	protein-L-isoaspartate(D-aspartate) O-methyltransferase	A0A1B1IU40	uncultured_Mediterranean_phage	3.7e-33	45.7
WP_012522512.1\|2193163_2193937_-	5'/3'-nucleotidase SurE	A0A1B1ITZ2	uncultured_Mediterranean_phage	3.4e-38	39.7
WP_012522513.1\|2193933_2195214_-\|tRNA	serine--tRNA ligase	A0A1B1IVT2	uncultured_Mediterranean_phage	2.5e-94	53.3
WP_012522514.1\|2195293_2196193_-	twin-arginine translocase subunit TatC	A0A1B1IVR7	uncultured_Mediterranean_phage	3.6e-39	37.9
WP_012522515.1\|2196189_2196726_-	twin-arginine translocase subunit TatB	NA	NA	NA	NA
WP_012522516.1\|2196799_2197012_-	twin-arginine translocase TatA/TatE family subunit	NA	NA	NA	NA
WP_012522517.1\|2197100_2197751_-	SMC-Scp complex subunit ScpB	A0A1B1IVT7	uncultured_Mediterranean_phage	6.3e-38	47.9
WP_012522518.1\|2197747_2198557_-	segregation/condensation protein A	A0A1B1IVW1	uncultured_Mediterranean_phage	3.2e-23	30.2
WP_012522519.1\|2198553_2199555_-	beta-N-acetylhexosaminidase	A0A1B1IVS3	uncultured_Mediterranean_phage	6.8e-23	45.6

Anti-CRISPR protein detection

Acr_ID: NC_011144.1|WP_012522179.1|1832085_1833555_-|D-glycero-beta-D-manno-heptose-1-phosphate-adenylyltransferase

Click the colored protein region to show detailed information

Acr ID

Acr position

Acr size

Homology with known anti

Neighbor HTH/AcRanker

Neighbor Aca

In prophage

Protospacer in prophage

NC_011144.1|WP_012522179.1|1832085_1833555_-|D-glycero-beta-D-manno-heptose-1-phosphate-adenylyltransferase

1832085_1833555_-

489 aa aa

1831087-1838789

yes

CRISPR ID	CRISPR type	Spacer info	Spacer location	Spacer length	Protospacer location	Mismatch
NC_011144_3	Orphan	3.4\|2030906\|16\|NC_011144\|CRISPRCasFinder	2030906-2030921	16	1832048-1832063	0

1. spacer 3.4|2030906|16|NC_011144|CRISPRCasFinder matches to NC_011144 position: 1832048-1832063, mismatch: 0

gaagcccgcgccgccg	CRISPR spacer
gaagcccgcgccgccg	Protospacer
****************

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. NC_011143

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection

2. NC_011144

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection

Click the colored protein region to show detailed information