CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NC_009673	Bacillus cytotoxicus NVH 391-98 plasmid pBC9801, complete sequence	0 crisprs	NA	0	0	0	0
NC_009674	Bacillus cytotoxicus NVH 391-98, complete sequence	3 crisprs	cas3,csa3,DinG,cas2,cas4,cas5,cas7,cas8b2,cas6,DEDDh,cas14j,WYL	0	6	7	0

Results visualization

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CRISPR-Cas detection and classification

Crispr_ID: NC_009674_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_009674_1

1542519-1542647

Orphan

Consensus_repeat	Method
AACTAGGGTGGTACCGCGATGTTTTAATCGTCCCTACG	CRISPRCasFinder

1 spacers

The CRISPR arrays of NC_009674_1

>merge|NC_009674|1|1542519-1542647|CRISPRCasFinder
AACTAGGGTGGTACCGCGATGTTTTAATCGTCCCTACGTATTTGCGTAGGGGCGTTTTTTATTGAAGGTCCTACTGTCGTTGTGTCTTCATAACTAGGGTGGTACCGCGATATTTTAATCGTCCCTACG

>NC_009674|1|1|1542519-1542647|CRISPRCasFinder
AACTAGGGTGGTACCGCGATGTTTTAATCGTCCCTACG	TATTTGCGTAGGGGCGTTTTTTATTGAAGGTCCTACTGTCGTTGTGTCTTCAT
AACTAGGGTGGTACCGCGATATTTTAATCGTCCCTACG

Protein	Signature genes	Signature genes Name	Protein_function
NC_009674.1\|WP_012093930.1\|1538264_1539473_+\|MFS-transporter	unknown	unknown	gnl\|CDD\|341031
NC_009674.1\|WP_012093934.1\|1544359_1544626_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|337191
NC_009674.1\|WP_012093940.1\|1550421_1551684_+\|threonine-ammonia-lyase-IlvA	unknown	unknown	gnl\|CDD\|236318
NC_009674.1\|WP_012093924.1\|1529429_1530806_+\|S-layer-homology-domain-containing-protein	unknown	unknown	gnl\|CDD\|226656
NC_009674.1\|WP_012093929.1\|1536406_1538047_-\|peptide-ABC-transporter-substrate-binding-protein	unknown	unknown	gnl\|CDD\|173869
NC_009674.1\|WP_012093939.1\|1548714_1550388_+\|dihydroxy-acid-dehydratase	unknown	unknown	gnl\|CDD\|234861
NC_009674.1\|WP_012093923.1\|1527299_1528532_-\|aspartate-kinase	unknown	unknown	gnl\|CDD\|235843
NC_009674.1\|WP_012093941.1\|1551905_1552625_+\|DUF554-domain-containing-protein	unknown	unknown	gnl\|CDD\|377371
NC_009674.1\|WP_081428362.1\|1548281_1548380_+\|helix-turn-helix-domain-containing-protein	unknown	unknown	gnl\|CDD\|378838
NC_009674.1\|WP_012093935.1\|1544765_1545404_+\|elongation-factor-G-binding-protein	unknown	unknown	gnl\|CDD\|319974
NC_009674.1\|WP_012093937.1\|1546883_1547783_+\|branched-chain-amino-acid-transaminase	unknown	unknown	gnl\|CDD\|183549
NC_009674.1\|WP_012093928.1\|1534735_1536304_+\|Vga-family-ABC-F-type-ribosomal-protection-protein	unknown	unknown	gnl\|CDD\|223562
NC_009674.1\|WP_012093933.1\|1542750_1544088_+\|sodium-dependent-transporter	unknown	unknown	gnl\|CDD\|271367
NC_009674.1\|WP_012093926.1\|1531833_1532646_+\|UDP-galactose-lipid-carrier-transferase	unknown	unknown	gnl\|CDD\|274736
NC_009674.1\|WP_012093936.1\|1545428_1545965_-\|peptide-methionine-(S)-S-oxide-reductase-MsrA	unknown	unknown	gnl\|CDD\|376578
NC_009674.1\|WP_012093932.1\|1540475_1542110_-\|polysaccharide-biosynthesis-protein	unknown	unknown	gnl\|CDD\|240529
NC_009674.1\|WP_164468624.1\|1548063_1548207_-\|hypothetical-protein	unknown	unknown	unknown
NC_009674.1\|WP_012093927.1\|1533144_1534404_+\|GTPase-HflX	unknown	unknown	gnl\|CDD\|274455
NC_009674.1\|WP_012093931.1\|1539488_1540406_+\|cysteine-synthase-A	unknown	unknown	gnl\|CDD\|273465
NC_009674.1\|WP_012093925.1\|1530861_1531326_-\|hypothetical-protein	unknown	unknown	unknown

Protein	Function_ID	Function_description	E-value
NC_009674.1\|WP_012093930.1\|1538264_1539473_+\|MFS-transporter	gnl\|CDD\|341031	cd17478, MFS_FsR, Fosmidomycin resistance protein of the Major Facilitator Superfamily of transporters. Fosmidomycin resistance protein (FsR) confers resistance against fosmidomycin. It shows sequence similarity with the bacterial drug-export proteins that mediate resistance to tetracycline and chloramphenicol. This FsR family belongs to the Major Facilitator Superfamily (MFS) of membrane transport proteins, which are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	1.4256e-102
NC_009674.1\|WP_012093934.1\|1544359_1544626_+\|hypothetical-protein	gnl\|CDD\|337191	pfam08765, Mor, Mor transcription activator family. Mor (Middle operon regulator) is a sequence specific DNA binding protein. It mediates transcription activation through its interactions with the C-terminal domains of the alpha and sigma subunits of bacterial RNA polymerase. The N terminal region of Mor is the dimerization region, and the C terminal contains a helix-turn-helix motif which binds DNA.	0.00419013
NC_009674.1\|WP_012093940.1\|1550421_1551684_+\|threonine-ammonia-lyase-IlvA	gnl\|CDD\|236318	PRK08639, PRK08639, threonine dehydratase; Validated.	0
NC_009674.1\|WP_012093924.1\|1529429_1530806_+\|S-layer-homology-domain-containing-protein	gnl\|CDD\|226656	COG4193, LytD, Beta- N-acetylglucosaminidase [Carbohydrate transport and metabolism].	1.27967e-24
NC_009674.1\|WP_012093929.1\|1536406_1538047_-\|peptide-ABC-transporter-substrate-binding-protein	gnl\|CDD\|173869	cd08504, PBP2_OppA, The substrate-binding component of an ABC-type oligopetide import system contains the type 2 periplasmic binding fold. This family represents the periplasmic substrate-binding component of an ATP-binding cassette (ABC)-type oligopeptide transport system comprised of 5 subunits. The transport system OppABCDEF contains two homologous integral membrane proteins OppB and OppF that form the translocation pore; two homologous nucleotide-binding domains OppD and OppF that drive the transport process through binding and hydrolysis of ATP; and the substrate-binding protein or receptor OppA that determines the substrate specificity of the transport system. The dipeptide (DppA) and oligopeptide (OppA) binding proteins differ in several ways. The DppA binds dipeptides and some tripeptides and is involved in chemotaxis toward dipeptides, whereas the OppA binds peptides of a wide range of lengths (2-35 amino acid residues) and plays a role in recycling of cell wall peptides, which precludes any involvement in chemotaxis. Most of other periplasmic binding proteins are comprised of only two globular subdomains corresponding to domains I and III of the dipeptide/oligopeptide binding proteins. The structural topology of these domains is most similar to that of the type 2 periplasmic binding proteins (PBP2), which are responsible for the uptake of a variety of substrates such as phosphate, sulfate, polysaccharides, lysine/arginine/ornithine, and histidine. The PBP2 bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap. After binding their specific ligand with high affinity, they can interact with a cognate membrane transport complex comprised of two integral membrane domains and two cytoplasmically located ATPase domains. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis. Besides transport proteins, the PBP2 superfamily includes the ligand-binding domains from ionotropic glutamate receptors, LysR-type transcriptional regulators, and unorthodox sensor proteins involved in signal transduction.	0
NC_009674.1\|WP_012093939.1\|1548714_1550388_+\|dihydroxy-acid-dehydratase	gnl\|CDD\|234861	PRK00911, PRK00911, dihydroxy-acid dehydratase; Provisional.	0
NC_009674.1\|WP_012093923.1\|1527299_1528532_-\|aspartate-kinase	gnl\|CDD\|235843	PRK06635, PRK06635, aspartate kinase; Reviewed.	0
NC_009674.1\|WP_081428362.1\|1548281_1548380_+\|helix-turn-helix-domain-containing-protein	gnl\|CDD\|378838	pfam12323, HTH_OrfB_IS605, Helix-turn-helix domain. This is the N terminal helix-turn-helix domain of Transposase_2 pfam01385.	0.000629588
NC_009674.1\|WP_012093935.1\|1544765_1545404_+\|elongation-factor-G-binding-protein	gnl\|CDD\|319974	cd16342, FusC_FusB, Fusidic acid resistance protein (FusC/FusB). The fusidic acid resistance protein FusC (FusB) mediates resistance to the antibiotic fusidic acid. Its C-terminal domain, which contains a zinc-binding site, interacts with EF-G with high affinity, promoting the dissociation of stalled ribosome#EF-G#GDP complexes that form in the presence of fusidic acid, thus allowing the ribosomes to resume translation.	2.03194e-116
NC_009674.1\|WP_012093937.1\|1546883_1547783_+\|branched-chain-amino-acid-transaminase	gnl\|CDD\|183549	PRK12479, PRK12479, branched-chain-amino-acid transaminase.	0
NC_009674.1\|WP_012093928.1\|1534735_1536304_+\|Vga-family-ABC-F-type-ribosomal-protection-protein	gnl\|CDD\|223562	COG0488, Uup, ATPase components of ABC transporters with duplicated ATPase domains [General function prediction only].	1.18883e-113
NC_009674.1\|WP_012093933.1\|1542750_1544088_+\|sodium-dependent-transporter	gnl\|CDD\|271367	cd10336, SLC6sbd_Tyt1-Like, solute carrier 6 subfamily, Fusobacterium nucleatum Tyt1-like; solute-binding domain. SLC6 proteins (also called the sodium- and chloride-dependent neurotransmitter transporter family or Na+/Cl--dependent transporter family) include neurotransmitter transporters (NTTs): these are sodium- and chloride-dependent plasma membrane transporters for the monoamine neurotransmitters serotonin (5-hydroxytryptamine), dopamine, and norepinephrine, and the amino acid neurotransmitters GABA and glycine. These NTTs are widely expressed in the mammalian brain, involved in regulating neurotransmitter signaling and homeostasis, and the target of a range of therapeutic drugs for the treatment of psychiatric diseases. Bacterial members of the SLC6 family include the LeuT amino acid transporter. An arrangement of 12 transmembrane (TM) helices appears to be as a common topological motif for eukaryotic and some prokaryotic and archaeal NTTs. However, this subfamily which contains the majority of bacterial members and some archaeal members, appears to contain only 11 TMs; for example the functional Fusobacterium nucleatum tyrosine transporter Tyt1.	0
NC_009674.1\|WP_012093926.1\|1531833_1532646_+\|UDP-galactose-lipid-carrier-transferase	gnl\|CDD\|274736	TIGR03708, poly_P_AMP_trns, polyphosphate:AMP phosphotransferase. Members of this protein family contain a domain duplication. The characterized member from Acinetobacter johnsonii is polyphosphate:AMP phosphotransferase (PAP), which can transfer the terminal phosphate from poly(P) to AMP, yielding ADP. In the opposite direction, this enzyme can synthesize poly(P). Each domain of this protein family is homologous to polyphosphate kinase, an enzyme that can run in the forward direction to extend a polyphosphate chain with a new terminal phosphate from ATP, or in reverse to make ATP (or GTP) from ADP (or GDP). [Central intermediary metabolism, Phosphorus compounds].	1.35596e-112
NC_009674.1\|WP_012093936.1\|1545428_1545965_-\|peptide-methionine-(S)-S-oxide-reductase-MsrA	gnl\|CDD\|376578	pfam01625, PMSR, Peptide methionine sulfoxide reductase. This enzyme repairs damaged proteins. Methionine sulfoxide in proteins is reduced to methionine.	4.36886e-93
NC_009674.1\|WP_012093932.1\|1540475_1542110_-\|polysaccharide-biosynthesis-protein	gnl\|CDD\|240529	cd13124, MATE_SpoVB_like, Stage V sporulation protein B, also known as Stage III sporulation protein F, and related proteins. The integral membrane protein SpoVB has been implicated in the biosynthesis of the peptidoglycan component of the spore cortex in Bacillus subtilis. This model represents a subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins. Proteins from the MATE family are involved in exporting metabolites across the cell membrane and are often responsible for multidrug resistance (MDR).	3.14857e-129
NC_009674.1\|WP_012093941.1\|1551905_1552625_+\|DUF554-domain-containing-protein	gnl\|CDD\|377371	pfam04474, DUF554, Protein of unknown function (DUF554). Family of uncharacterized prokaryotic proteins. Multiple predicted transmembrane regions suggest that the region is membrane associated.	5.0023e-73
NC_009674.1\|WP_012093927.1\|1533144_1534404_+\|GTPase-HflX	gnl\|CDD\|274455	TIGR03156, GTP_HflX, GTP-binding protein HflX. This protein family is one of a number of homologous small, well-conserved GTP-binding proteins with pleiotropic effects. Bacterial members are designated HflX, following the naming convention in Escherichia coli where HflX is encoded immediately downstream of the RNA chaperone Hfq, and immediately upstream of HflKC, a membrane-associated protease pair with an important housekeeping function. Over large numbers of other bacterial genomes, the pairing with hfq is more significant than with hflK and hlfC. The gene from Homo sapiens in this family has been named PGPL (pseudoautosomal GTP-binding protein-like). [Unknown function, General].	0
NC_009674.1\|WP_012093931.1\|1539488_1540406_+\|cysteine-synthase-A	gnl\|CDD\|273465	TIGR01139, Cysteine_synthase, cysteine synthase A. This model distinguishes cysteine synthase A (CysK) from cysteine synthase B (CysM). CysM differs in having a broader specificity that also allows the use of thiosulfate to produce cysteine thiosulfonate. [Amino acid biosynthesis, Serine family].	1.17556e-161

>NC_009674.1|WP_012093932.1|1540475_1542110_-|polysaccharide-biosynthesis-protein
MSTSKVLKGTALLSGATMISRILGFIYFFPFQLLVGTQGVALYGYAYSWYGILLSFSTAGIPIAVSKFVAKYNALGDYSTSKKLYNSSVKLMLLMGFSGFFILFIGAPYISQFIIRSKAPDPKFIADVTLTMRALSFALIIVPAMSVTRGYFQGFQHMKPSAVSQVVEQIARVVFILVGSFVVTKLLGGSVASSVAVATFGAAVGAIASVSILIMYWKKYNHLKPPKGELKSRASTLPLKSIYMELLRYAIPIVFVGIAIPLYTLVDQYTVADALRALGEPLTTANAVFAYIANYAQKLIMIPASLATGFSLTIIPAITKSFTSGKQEELQEQITKIFQVLLFFTIPAAFGLASIAYDAFRMVYVSHDIAVGGSQYLISYAPSAVLSAIFTVSAAILQGIDYQRKTMIAFSVGILVKLIVNTPLLYVLGGHGAVLGTILGYLVSDAIMLYCIVKFAKFDIKETIKTVCLIIIYSGAMSAIVMALKAMIGWFIPGQSYIESLLIVIICGVVGGFVYLLFVLTSGLASRILGNRIQRLPILGKFIK
>NC_009674.1|WP_012093931.1|1539488_1540406_+|cysteine-synthase-A
MKLCKNVTELIGDTPVVRLSKFVPKDAADVYVKLEMFNPSRSVKDRAAYHLIHVAEEQGFIQPGDTIIEPTSGNTGIGLAMNAAAKGYKAILIMPDNMSKERMNLLKAYGAEVILTPAEQRMPGAIAKAIELQKQIPNSFIPQQFENPANPNIHRYTTALEIYEQMEGKLDAFVATAGTGGTITGTGETLKEKLPNLHIVVVEPKGSPVLSGGVPGPHKLVGTSPGFIPKNLNTEIYNEIIQIADEEALSTMRNLAKQEGLLVGPSSGASVYAAIMIAKRLGAGKKVLCIAPDTGERYLSMGLFE
>NC_009674.1|WP_012093930.1|1538264_1539473_+|MFS-transporter
MQAISKENVVTTPTIYRILFAISFGHFLNDSMQAVVPALFPILEKTMNLSYMQVGWIAFALNMTSSVMQPVFGMYSDKKPSPFLLPLGMFSSMLGMIGLAFAPNFIIVIISVLFIGLGSAVFHPEGARVAYMASGTKRGLAQAIYQVGGNTGNSLAPIFTAVIFVPLGQKGSLGFTAFAAVGILLLMYVSKWYKNELVSGAVKSKKRAALEAENAIVSAHIKFVIVLLIFLTFVRSWYGAGIGNFYQFYLIEHYGLSIKNAQYFVFAFMISGVLGTFFGGPLADRFGKKNIIVFSMLGSAPLALLLPHVSLLWVVPLFLCIGFISSSSFSVIVVYAQELVPGKVGMVSGLIVGLAFGLGALGAVVLGKLADIYSLQFIMVLCSCLPLIGLTSWLLPSDKKSV
>NC_009674.1|WP_012093929.1|1536406_1538047_-|peptide-ABC-transporter-substrate-binding-protein
MKKKTKRVAALSLTLSLVLTACGQKQETTTNKDEKKVATKQILNIVETGEISTLDSSIATDGFSYAALNNVMEGLYMPGPGNKPVPGAAESYTLSEDGKTYIFKLRHSNWSNGDPVTAHDFEYAWKRAINPETASEYAHIMFDIKNAEKVNKKALPLDSFGVKALDDKTLEVQLEHPVPYFLGLMGFATFYPQNQKVVEAQGTNYGLEAANAVYNGPFVLNEWKHDTSYKMTKNPNYWDHKNVKLQEINVNIVKDTSAAVNLFESKQVDRITINSEFVDKYQNDPSLKKMARPSVTFFRLNQKNPLLANKNARKAISLSFDKKGITTTILNNGSIPANAFIPKGFVKGPDNKDFRSTSNVKVETNIKEAKKQWETAKKETNLQNVSLSIISTDESNDKKISEYLKGELEKNLPGLKITLNPLPVKAFLEREGNGDFEISLSTWGPDYPDPTTFLNMFVTDGPFNKMNYSNKQYDELMEKASSSLTTDLPARWKAFQDAEKILVEDDAAIAPIFQAGLIYLERPSVKGVVVRPFAGIYSYKWAYITE
>NC_009674.1|WP_012093928.1|1534735_1536304_+|Vga-family-ABC-F-type-ribosomal-protection-protein
MLLLEANRIKYYIQDRLLLDIDQLQIHQNARIGLVGRNGSGKTTLFQILAKEIVPEEGSIVQRVRCELLPQLKQTDTTKSGGEVTQEYIQKAVLKDPELLLADEPTTNLDTGHIEWLEKKLGNWKGAFVIISHDRAFLDALCTTIWELDEGKIKVYTGNYSEYVKQKEIERQQEQLAYEKYEKKKKQLEEAVKLKEKKAERATKTPKKEGKLEPKITKPYFAKKQKKLQKTATAMITRLEKLGKVEKVKELPPLKMDLPNAETFKNRIILRVNDRIGKVGKRVLWKKASFHIRGGDKLAIIGANGSGKTTLVKQIMNQEYGIRFSPAVKVGYFSQNLNILDPAKSIIENVQSSSKQNETLIRTVLARMHFFREDVYKLVEVLSGGERVKVALTKLFLSDINTLILDEPTNFLDMTAVEALESLLKEYEGSVIFVSHDRRFIENIATRILTIHNQELGLFEGTYQQYKRTQVQQAQERKKDTRLLLETKLSEVLSRLSIEPSEKLEREFEKLLQEKRELDASE
>NC_009674.1|WP_012093927.1|1533144_1534404_+|GTPase-HflX
MEEFVQRAILVGVNLGHESDFQYSMEELANLAEACDVEVVGQVTQNLQRVNPSHYIGTGKIGEVAAYVKEVDANIVIFNDELSPSQIRNLEKDLDCKVIDRTILILDIFAQRAKTKEAQLQVEVAHLQYMMPRLVGLRESLGRQSGGVGTKNKGVGEKKLELDRRKIEEQISVLNKELEALVVQRKTQRKQRKKNEIPVVALVGYTNAGKSTTMNAMLEIFNGTIEKQVFEKDMLFATLETSVRNIELPDNKSFLLTDTVGFVSKLPHHLVKAFRSTLEEVAEADLLIHVVDYSNPNYEQLIEITNQTLKQIGVENIPTIYAYNKSDMMDVEIPKTKKDRVYLSAKKQIGMEELVEMIRSHIYKEYTKCEMLIPYDQGQIVSYFNEYAHVICTSYENEGTKLSLECKISDFEKYKRFAI
>NC_009674.1|WP_012093926.1|1531833_1532646_+|UDP-galactose-lipid-carrier-transferase
MKKEWLANVDLTKKIDSKSKYNKKLKKYQRHLLALQQILKEEKVAVIMVMEGWDAAGKGGAIKRVTEHLDPRGFQVKPIAAPAPHEKRYHYLQRFWREIPRYGQIAIFDRSWYGRVLVERVEGFATQEEWARAYDEINDFEKVLTDDHYIIGKFFYHMSKDEQLKRFKERENNPLKRWKITDEDWRNREKWDEYVEAMEEMFEKTNQPNAKWHIIASNNKLYARVKTLKVMISLIEDYFLEHGIELPSYYYEIKAEQQEEFEIVQDVSMK
>NC_009674.1|WP_012093925.1|1530861_1531326_-|hypothetical-protein
MKRKIFFLLTLLCIVLPIQVSAFTFQELPVASKSKQWYIEIDKSYNSNKQAIQPKQGVYDTYSLFVKNIGKDVSNVSIEIVGNDPSAKTTFKPTVPHTNVSKSHTSFDYMVFPLYFTSHTFKVIMTWEEKEFTYNGHPESKSKKMKQTFIFTEE
>NC_009674.1|WP_012093924.1|1529429_1530806_+|S-layer-homology-domain-containing-protein
MKKVISNVLAMTAALQVIMVPTTSFAAEKGFSDVPKSHWAYEAINDLANRNIIAGYDNGKFGLGDSVTREQVAALIYRALKPEAKAEYKNPYHDVSASTTMFPNEILALTEMGIFTGDENKNFRPKDSLTRAEMAMILQRAYHLKVKANHTFHDVDPNSWAKDAISALQSNGMAEGDGTGAFYPSKTVTREEYAQFLFNAEQSYLNLDLTLASNVTAEEIDNFLKKSRSDSPLIGHGQDFIAAQNEHGVNALYLAAHAILESGYGRSEIAYRKHNLFGLRAYDRDPFYHAKYLPTYRDSISYNANYVRERYLEKGAIYYNGPTLVGMNVKYASDPEWAGKIAGLMERIKPFDRNDYKNANRLPKNPHTLDVEALGNEIPYKDLGNREIAVQASGKYYKVPYPYDLKIKSIPDITQNEMGTLTNGSKVTVHREDPNGWVEFSMKDKQEKYWTLKSNLKM
>NC_009674.1|WP_012093923.1|1527299_1528532_-|aspartate-kinase
METIVQKFGGTSVGNIQRIQHVANLMIEEYEKGHNVVTVVSAMGKSTDKLVALATSITENPSKRELDMLLTTGEQVTISLLTMALQTKGYQAISLTGWQAGITTEPVHGNARITDIHTERIQSYLQEGTIVIVAGFQGLSEEKEITTLGRGGSDTTAVALAAALKAKKCDIYTDVTGVYTTDPRVVNNAYKLDEISYDEMLELANLGAGVLHPRAVEFAKNHNVVLEVRSSMEQENGTIVRGECNMEQQSIVKGIAFEDNITRVTIKGLEHDSLSTIFSTLAEAHINVDIIIQSITNEGTVHLSFSIHSNDLRETLEALKQNQETLHYESVEYENHLAKVSIVGSGMVSNPGVAAHMFSTLKEENIHVKMVSTSEIKISVVIDRLHLVDGVEALHQAFMTKVEPLVQMNK
>NC_009674.1|WP_012093933.1|1542750_1544088_+|sodium-dependent-transporter
MNSPQWTSKLGFVLAAAGSAIGLGAIWKFPYMAGIGGGGAFFLIFIGFTLLIGLPLLLAEFVIGRSTQKEAVDAYRQIAPKTLWPWLGKLGVVTCFILLSFYSVVGGWILLYLWNAITGRLWEGNGAYEATFGEIISNPYLAVGSQLLFILMTIFIVSKGVQNGVEKVNKYFMPALFVLFFILIIRALTLDGAGEGVRFFLQPDFSNVTSEIILYAMGQSFFSLSVGVAVMVTYSSYLPKEESLPRSAFSIVGLTLMITLLAGLAIFPVVFAFGMEPSQGPGLLFIVLPAIFSKMAFGKVFFVIFLLLFFFATVTSAISMLEISVASLTAKGNGRREKFAIIVGLLIFVVGIPSALSYGVLSDFKVFGKTVFDLADFAVSNVLMPLGVLLVSIFVPLKMKKDVLMRELGVSKHKGYTLFILWLFLLRYIAPVAIIIVFLNVIGVI
>NC_009674.1|WP_012093934.1|1544359_1544626_+|hypothetical-protein
MGYVKATAVLPESLIAEIQKYVQGETIYIPKQETEHYKWGTRSGGRKQIDMRNRKIKEAFENGIAIYQLAEEYFLSVETIKKIVYSKS
>NC_009674.1|WP_012093935.1|1544765_1545404_+|elongation-factor-G-binding-protein
MEAFIRSDQYNFIKSQTHILVHGHATANDRGVITALKSLAIEKVLHAFENLNSEQKELIETILAVENREDAEAFLLKLNPYVIPFQEVTPQALKKLFPKVKKLKLPEMEEVNMKEMSYLGWTDKGTGKRFIIAKKNNKLVGVQGTFQSINKKGICALCHGHEEVGMFLVEIKGDVPGTFVKKGNYICQDSIACNQNMTSLDKLHDFIERLKK
>NC_009674.1|WP_012093936.1|1545428_1545965_-|peptide-methionine-(S)-S-oxide-reductase-MsrA
MSKKTFELATFAGGCFWCMVKPFDELPGIQKVVSGYTGGHISNPTYEQVKSGTSGHLEVVQMTFDPSIFPYQKLLDLYWSQIDPTDDGGQFFDRGPSYRTAIFYHNETQKELAEKSKQLLATSGIFNEPIVTEIRPAAPFYEAEEYHQHFYKKNPKKYAQERKESGREDFIKTNWQKK
>NC_009674.1|WP_012093937.1|1546883_1547783_+|branched-chain-amino-acid-transaminase
MKKQYIYMNGELVEKEKAVVSVYDHGFLYGDGVFEGIRSYGGNVFCLKEHVKRLYESAKSILLTIPMTVEEMEKAVVQTLQKNGYADAYIRLIVSRGKGDLGLDPRSCEKPSVIIIAEQLKLFPQEFYDNGLSVVSVASRRNMPDALDPRIKSMNYLNNVLVKIEAAQAGALEALMLNQQGYVCEGSGDNVFVVKDGKVVTPPSYLGALEGVTRNSVIELCDKLGIPCEERPFTRHDVYVADEVFLTGTAAELIPVVKVDAREIGDGKPGEVTKQLTEAFKRLTRERGVRVPGLAESLA
>NC_009674.1|WP_164468624.1|1548063_1548207_-|hypothetical-protein
MERISKLITFPADLVAEIEKYQKENYITSFAGAVYELIRKGLSVSDR
>NC_009674.1|WP_081428362.1|1548281_1548380_+|helix-turn-helix-domain-containing-protein
MLVNKVYKFRIYPNKGQEILKQVVDVLQVNTS
>NC_009674.1|WP_012093939.1|1548714_1550388_+|dihydroxy-acid-dehydratase
MRSDMIKKGFDKAPHRSLLKATGLKDEDFHKPFVAICNSFIEIIPGHKHLNEFGRLVKEAVRAAGMVPFEFNTIGVDDGIAMGHIGMRYSLPSREIIADSVETVVNAHWFDGMICIPNCDKITPGMMMAAMRINIPTVFVSGGPMAAGKTSKGEVVDLSSVFEGVGAYQSGKISEEELKDIEDHGCPSCGSCSGMFTANSMNCLCEVLGLALPGNGSILATDSRREQLIQRAAESLKILMERDIKPRDIVTEEAIDDAFALDMAMGGSTNTVLHTLAIAQEAGLDYDMNRIDAVSRKVPHLCKVSPASNWHMEDIDRAGGMSAILKELSRKEGVLHFDRITVTGKTLRENIADAEIQDKEVIHSLENPHSQEGGLRILKGNLAKDGAVIKSGATEVKRFEGPCVIFNSQDEALAGIMLGKVKKGDVVVIRYEGPRGGPGMPEMLAPTSAIAGMGLGADVALLTDGRFSGASRGISVGHISPEAAAGGEIALLQQGDIVCIDVEERLLEVKVSDEELAKRRKEWKRPEPKVKTGWLGRYAQMVTSANTGAVLKMQNFD
>NC_009674.1|WP_012093940.1|1550421_1551684_+|threonine-ammonia-lyase-IlvA
MVHKVKERVKIEDILMAHNCLKDIVNKTPLQRDAVLSEKYKCEVYVKREDLQVIRSFKIRGAYNLIQSLSKEKLQNGVVCASAGNHAQGVAYTCNLLEIPANIFMPTTTPKQKVSQVKFFGGDVADIMLVGDTFDSSFQEAQRYCEENGMTFVHPFDDPHVIAGQGTVAVEILHDTEKTIDYVFTAIGGGGLASGIGTYVKGVSPNTKVIGVEPKGAASMKEAFLQNENVTLEMIDSFVDGAAVKKVGKLTFETCKDVLDDIVLVPEGKICTTILELYKKNAIVAEPAGALSIAALDFYKDEIKGKTVVCVLSGGNNDIDRMQEMKERSLIYEGIKHYFIIQFPQRSGALREFLDKGLGPEDDITRFEYIKKHNKENGPALVGVELKHKEDYEPLIARFKENHIQFLELNKNPVLFDLLT
>NC_009674.1|WP_012093941.1|1551905_1552625_+|DUF554-domain-containing-protein
MVILGAIVNGICIIIGTLLGKVLSNIPESMKGTVMHAIGLAVTVLGLRMGMKSEIFLIVILSLVIGSVVGEWLCLEEKLQKLGNWLEKKVGSKGEGSISVGFVTATLIFAIGAMGVLGALDSGIRGNHNVLYTKAIIDGFISLILTTTLGIGVLFSAVPVILYEGGIALFATKIDRFVPEQLMNQFIIEMTATGGIMIFAIGLNLLGFIKIKVANLLPGILVVGMIVSIIYGYNLFLLK

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Crispr_ID: NC_009674_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_009674_2

2126031-2126385

Unclear

I-A

Consensus_repeat	Method
CTTTATATCCCACTACGTTCAGATAAAAC	CRISPRCasFinder
CTTTATATCCCACTACGTTCAGATAAAAC	CRT
CTTTATATCCCACTACGTTCAGATAAAAC	PILER-CR

5 spacers

cas2,cas4,cas3,cas5,cas7,cas8b2,cas6

The CRISPR arrays of NC_009674_2

>merge|NC_009674|2|2126031-2126385|CRISPRCasFinder,CRT,PILER-CR
CTTTCTATTCCACTACGTTCAGATAAAACTCCACATAGAAGCATTGTGAATCATAATTTTTGCTGTCTTTATATCCCACTACGTTCAGATAAAACGCGAATGGTATGTGCTGAAGACTATCAAAAAATAACCTTTATATCCCACTACGTTCAGATAAAACTTTTGGTCGTTACCTGTATGTGTGTTTACCTCCATGACTTTATATCCCACTACGTTCAGATAAAACCTTTTTTGGTCTCGCAGCTTTCCACATCATGAATTTCTTTATATCCCACTACGTTCAGATAAAACCCTTAAAGCTACAGCGAACGTTAAGCGGTCATTGACTTTATATCCCACTACGTTCAGATAAAAC

>NC_009674|2|2|2126031-2126385|CRISPRCasFinder
CTTTCTATTCCACTACGTTCAGATAAAAC	TCCACATAGAAGCATTGTGAATCATAATTTTTGCTGT
CTTTATATCCCACTACGTTCAGATAAAAC	GCGAATGGTATGTGCTGAAGACTATCAAAAAATAAC
CTTTATATCCCACTACGTTCAGATAAAAC	TTTTGGTCGTTACCTGTATGTGTGTTTACCTCCATGA
CTTTATATCCCACTACGTTCAGATAAAAC	CTTTTTTGGTCTCGCAGCTTTCCACATCATGAATTT
CTTTATATCCCACTACGTTCAGATAAAAC	CCTTAAAGCTACAGCGAACGTTAAGCGGTCATTGA
CTTTATATCCCACTACGTTCAGATAAAAC

>NC_009674|2|1|2126031-2126385|CRT
CTTTCTATTCCACTACGTTCAGATAAAAC	TCCACATAGAAGCATTGTGAATCATAATTTTTGCTGT
CTTTATATCCCACTACGTTCAGATAAAAC	GCGAATGGTATGTGCTGAAGACTATCAAAAAATAAC
CTTTATATCCCACTACGTTCAGATAAAAC	TTTTGGTCGTTACCTGTATGTGTGTTTACCTCCATGA
CTTTATATCCCACTACGTTCAGATAAAAC	CTTTTTTGGTCTCGCAGCTTTCCACATCATGAATTT
CTTTATATCCCACTACGTTCAGATAAAAC	CCTTAAAGCTACAGCGAACGTTAAGCGGTCATTGA
CTTTATATCCCACTACGTTCAGATAAAAC

>NC_009674|2|1|2126097-2126385|PILER-CR
CTTTATATCCCACTACGTTCAGATAAAAC	GCGAATGGTATGTGCTGAAGACTATCAAAAAATAAC
CTTTATATCCCACTACGTTCAGATAAAAC	TTTTGGTCGTTACCTGTATGTGTGTTTACCTCCATGA
CTTTATATCCCACTACGTTCAGATAAAAC	CTTTTTTGGTCTCGCAGCTTTCCACATCATGAATTT
CTTTATATCCCACTACGTTCAGATAAAAC	CCTTAAAGCTACAGCGAACGTTAAGCGGTCATTGA
CTTTATATCCCACTACGTTCAGATAAAAC

Protein	Signature genes	Signature genes Name	Protein_function
NC_009674.1\|WP_012094487.1\|2127852_2128350_-\|CRISPR-associated-protein-Cas4	cas4	pfam01930_cas4_CAS-I	gnl\|CDD\|366863
NC_009674.1\|WP_041809787.1\|2124544_2124925_-\|VOC-family-protein	unknown	unknown	gnl\|CDD\|319924
NC_009674.1\|WP_012094494.1\|2136507_2136834_-\|antibiotic-biosynthesis-monooxygenase	unknown	unknown	gnl\|CDD\|225209
NC_009674.1\|WP_012094493.1\|2134020_2134722_-\|CRISPR-associated-endoribonuclease-Cas6	cas6	pfam01881_cas6_CAS-I:CAS-III	gnl\|CDD\|187783
NC_009674.1\|WP_012094477.1\|2112411_2114385_-\|LTA-synthase-family-protein	unknown	unknown	gnl\|CDD\|224287
NC_009674.1\|WP_109090138.1\|2125162_2125336_-\|DUF2332-family-protein	unknown	unknown	gnl\|CDD\|378386
NC_009674.1\|WP_012094490.1\|2130691_2131390_-\|type-I-B-CRISPR-associated-protein-Cas5	cas5	cd09658_cas5_CAS-I-B	gnl\|CDD\|187789
NC_009674.1\|WP_012094485.1\|2125653_2125800_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|376564
NC_009674.1\|WP_012094478.1\|2114858_2116484_-\|ATP-binding-cassette-domain-containing-protein	unknown	unknown	gnl\|CDD\|237894
NC_009674.1\|WP_041809784.1\|2118734_2122265_-\|DUF4020-domain-containing-protein	unknown	unknown	gnl\|CDD\|238697
NC_009674.1\|WP_012094496.1\|2137758_2137974_-\|uridine-kinase	unknown	unknown	gnl\|CDD\|169051
NC_009674.1\|WP_012094495.1\|2137175_2137520_+\|hypothetical-protein	unknown	unknown	unknown
NC_009674.1\|WP_012094486.1\|2126608_2126872_-\|CRISPR-associated-endonuclease-Cas2	cas2	cd09725_cas2_CAS-I:CAS-II:CAS-III:CAS-V	gnl\|CDD\|187856
NC_009674.1\|WP_109456139.1\|2128412_2130647_-\|CRISPR-associated-helicase-Cas3'	cas3	COG1203_cas3_CAS-I	gnl\|CDD\|273707
NC_009674.1\|WP_041810408.1\|2122908_2124234_-\|D-serine-ammonia-lyase	unknown	unknown	gnl\|CDD\|235096
NC_009674.1\|WP_012094491.1\|2131386_2132280_-\|type-I-B-CRISPR-associated-protein-Cas7/Cst2/DevR	cas7	cd09687_cas7_CAS-I-B	gnl\|CDD\|187818
NC_009674.1\|WP_012094479.1\|2116890_2117967_-\|bifunctional-3-deoxy-7-phosphoheptulonate-synthase/chorismate-mutase	unknown	unknown	gnl\|CDD\|183614
NC_009674.1\|WP_012094476.1\|2109670_2111776_-\|transcription-antiterminator	unknown	unknown	gnl\|CDD\|226234
NC_009674.1\|WP_012094481.1\|2122424_2122862_+\|YndM-family-protein	unknown	unknown	gnl\|CDD\|371204
NC_009674.1\|WP_012094492.1\|2132272_2134021_-\|type-I-B-CRISPR-associated-protein-Cas8b1/Cst1	cas8b2	cd09665_cas8b2_CAS-I-B	gnl\|CDD\|187796

Protein	Function_ID	Function_description	E-value
NC_009674.1\|WP_012094487.1\|2127852_2128350_-\|CRISPR-associated-protein-Cas4	gnl\|CDD\|366863	pfam01930, Cas_Cas4, Domain of unknown function DUF83. This domain has no known function. The domain contains three conserved cysteines at its C-terminus.	3.71199e-58
NC_009674.1\|WP_041809787.1\|2124544_2124925_-\|VOC-family-protein	gnl\|CDD\|319924	cd07263, VOC_like, uncharacterized subfamily of vicinal oxygen chelate (VOC) family. The vicinal oxygen chelate (VOC) superfamily is composed of structurally related proteins with paired beta.alpha.beta.beta.beta motifs that provide a metal coordination environment with two or three open or readily accessible coordination sites to promote direct electrophilic participation of the metal ion in catalysis. VOC domain is found in a variety of structurally related metalloproteins, including the bleomycin resistance protein, glyoxalase I, and type I ring-cleaving dioxygenases. A bound metal ion is required for protein activities for the members of this superfamily. A variety of metal ions have been found in the catalytic centers of these proteins including Fe(II), Mn(II), Zn(II), Ni(II) and Mg(II). The protein superfamily contains members with or without domain swapping. The proteins of this family share three conserved metal binding amino acids with the type I extradiol dioxygenases, which shows no domain swapping.	1.49534e-44
NC_009674.1\|WP_012094494.1\|2136507_2136834_-\|antibiotic-biosynthesis-monooxygenase	gnl\|CDD\|225209	COG2329, COG2329, Uncharacterized enzyme involved in biosynthesis of extracellular polysaccharides [General function prediction only].	5.76195e-19
NC_009674.1\|WP_012094493.1\|2134020_2134722_-\|CRISPR-associated-endoribonuclease-Cas6	gnl\|CDD\|187783	cd09652, Cas6-I-III, CRISPR/Cas system-associated RAMP superfamily protein Cas6. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas6 is an endoribonuclease that generates crRNAs, predicted subunit of Cascade complex; RAMP superfamily protein; Possesses double RRM/ferredoxin fold.	1.0641e-22
NC_009674.1\|WP_012094477.1\|2112411_2114385_-\|LTA-synthase-family-protein	gnl\|CDD\|224287	COG1368, MdoB, Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily [Cell envelope biogenesis, outer membrane].	0
NC_009674.1\|WP_109090138.1\|2125162_2125336_-\|DUF2332-family-protein	gnl\|CDD\|378386	pfam10094, DUF2332, Uncharacterized protein conserved in bacteria (DUF2332). Members of this family of hypothetical bacterial proteins have no known function.	1.71552e-08
NC_009674.1\|WP_012094490.1\|2130691_2131390_-\|type-I-B-CRISPR-associated-protein-Cas5	gnl\|CDD\|187789	cd09658, Cas5_I-B, CRISPR/Cas system-associated RAMP superfamily protein Cas5. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas5 is a RAMP superfamily protein; Subunit of the Cascade complex.	2.84624e-29
NC_009674.1\|WP_012094485.1\|2125653_2125800_-\|hypothetical-protein	gnl\|CDD\|376564	pfam01548, DEDD_Tnp_IS110, Transposase. Transposase proteins are necessary for efficient DNA transposition. This family includes an amino-terminal region of the pilin gene inverting protein (PIVML) and of members of the IS111A/IS1328/IS1533 family of transposases. The C-terminus is represented by family pfam02371.	0.00255682
NC_009674.1\|WP_012094478.1\|2114858_2116484_-\|ATP-binding-cassette-domain-containing-protein	gnl\|CDD\|237894	PRK15064, PRK15064, ABC transporter ATP-binding protein; Provisional.	0
NC_009674.1\|WP_041809784.1\|2118734_2122265_-\|DUF4020-domain-containing-protein	gnl\|CDD\|238697	cd01406, SIR2-like, Sir2-like: Prokaryotic group of uncharacterized Sir2-like proteins which lack certain key catalytic residues and conserved zinc binding cysteines; and are members of the SIR2 superfamily of proteins, silent information regulator 2 (Sir2) enzymes which catalyze NAD+-dependent protein/histone deacetylation.	5.91122e-54
NC_009674.1\|WP_012094496.1\|2137758_2137974_-\|uridine-kinase	gnl\|CDD\|169051	PRK07667, PRK07667, uridine kinase; Provisional.	8.82097e-32
NC_009674.1\|WP_012094486.1\|2126608_2126872_-\|CRISPR-associated-endonuclease-Cas2	gnl\|CDD\|187856	cd09725, Cas2_I_II_III, CRISPR/Cas system-associated protein Cas2. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas2 is present in majority of CRISPR/Cas systems along with Cas1; RNAse specific to U-rich regions; Possesses an RRM/ferredoxin fold.	2.02502e-27
NC_009674.1\|WP_109456139.1\|2128412_2130647_-\|CRISPR-associated-helicase-Cas3'	gnl\|CDD\|273707	TIGR01587, CRISPR-associated_endonuclease/helicase_Cas3, CRISPR-associated helicase Cas3. This model represents the highly conserved core region of an alignment of Cas3, a protein found in association with CRISPR repeat elements in a broad range of bacteria and archaea. Cas3 appears to be a helicase, with regions found by pfam00270 (DEAD/DEAH box helicase) and pfam00271 (Helicase conserved C-terminal domain). Some but not all members have an N-terminal HD domain region (pfam01966) that is not included within this model.	8.75921e-63
NC_009674.1\|WP_041810408.1\|2122908_2124234_-\|D-serine-ammonia-lyase	gnl\|CDD\|235096	PRK02991, PRK02991, D-serine dehydratase; Provisional.	0
NC_009674.1\|WP_012094491.1\|2131386_2132280_-\|type-I-B-CRISPR-associated-protein-Cas7/Cst2/DevR	gnl\|CDD\|187818	cd09687, Cas7_I-C, CRISPR/Cas system-associated RAMP superfamily protein Cas7. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas7 is a RAMP superfamily protein; Subunit of the Cascade complex; also known as Cst2/DevR family.	4.74396e-53
NC_009674.1\|WP_012094479.1\|2116890_2117967_-\|bifunctional-3-deoxy-7-phosphoheptulonate-synthase/chorismate-mutase	gnl\|CDD\|183614	PRK12595, PRK12595, bifunctional 3-deoxy-7-phosphoheptulonate synthase/chorismate mutase; Reviewed.	0
NC_009674.1\|WP_012094476.1\|2109670_2111776_-\|transcription-antiterminator	gnl\|CDD\|226234	COG3711, BglG, Transcriptional antiterminator [Transcription].	1.41328e-55
NC_009674.1\|WP_012094481.1\|2122424_2122862_+\|YndM-family-protein	gnl\|CDD\|371204	pfam10710, DUF2512, Protein of unknown function (DUF2512). Proteins in this family are predicted to be integral membrane proteins, and many of them are annotated as being YndM protein. They are all found in Firmicutes. The true function is not known.	2.79979e-37
NC_009674.1\|WP_012094492.1\|2132272_2134021_-\|type-I-B-CRISPR-associated-protein-Cas8b1/Cst1	gnl\|CDD\|187796	cd09665, Cas8a1_I-A, CRISPR/Cas system-associated protein Cas8a1. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Large proteins, some contain Zn-finger domain; signature gene for I-A subtype; also known as CXXC_CXXC family.	1.471e-10

>NC_009674.1|WP_012094485.1|2125653_2125800_-|hypothetical-protein
MKDTTKYVGLDVSKEKIAVAIADEGREEPRYLGMIPHTPESLRKLIKN
>NC_009674.1|WP_109090138.1|2125162_2125336_-|DUF2332-family-protein
MGKDLKVSFISVKLIEGDRVALLAEIVEKIPKEFAICIFHTHVAKQMSESVKHGLIE
>NC_009674.1|WP_041809787.1|2124544_2124925_-|VOC-family-protein
MIHKVGQIMLYVKDQDEAVQFWTEKMGFHLIAEEDNGKGFRWIEIAPTKEAETSIVLHNKEFIAKMQPELNLNTPSMLFFTENIEQLHKQLVDKKVEVGEIVNMPTGKAFNFADDEGNYFAIMEKS
>NC_009674.1|WP_041810408.1|2122908_2124234_-|D-serine-ammonia-lyase
MIKGKTIRKWTEENPILRQLIETSEVFWENPNYSSYEKARQDFVLTTEDVKEAEARLLRFAPYIAKVFPETKEMDGIIESPLVETMHMKQYLEDAFAQEMPGRFLLKCDNNLPISGSIKARGGIYEVLQHAEKLAIEHNLLCEEDHYAKLDSDRFREFFSQYSIAVGSTGNLGLSIGIMSAKLGFQVTVHMSADAKEWKKELLRNKGVTVVEYESDYSKAVEEGRKQAEQDPHCYFIDDENSKHLFLGYAVAASRVKQQLEDKNIRVDKDHPLFVYLPCGVGGGPGGVAFGLKLLFGDAVHCFFAEPTHSPCMLLGLVTGLHDEIAVQDFEIDNVTEADGLAVGRASGFVGKIMEPLLSGCYTVEDQQLYELLKAMVDTENIRLEPSALAAVYGPVQLYRQENYVKRHKLEGKMNRSTHMMWATGGGMVPKSVFDEYYQNQ
>NC_009674.1|WP_012094481.1|2122424_2122862_+|YndM-family-protein
MSDIALVLIKFISCIIAFAIGLALFFPATLVQIISFSLFVTIISYVFVDKIILERIGRSAAIMTDFLLTYLSVWIFGNILLDHYMQIAWGSILSALVFTLCEVIVQRFSHAHERHNSDNIHLNRRFSYGTEFAEEQNPLDKNKKK
>NC_009674.1|WP_041809784.1|2118734_2122265_-|DUF4020-domain-containing-protein
MTFLGKEGIRMWITSEVEIPEELFDHLEQGKLVLFVGAGVSMKGKSNLPNFDDLVDEIAKALYVEKREITEPHDYYLGKIAKTKDVHQIAKDLVNVEGSKPNPLHYAIPRLFPKDTDVRIVTTNFDQHFTTAMRESDRDFNIYYAPALPTGRAFKGLAYIHGNVEQEKENLILTDGDFGRAYLTEGWARRFLVDLFSNYTVLFIGYSHNDPVMKYLATGLPPSTRRYAFVAHGDNTYHWEHLGVKPIVYPNKANNHQALVRAVKRWAELMGDNYITKRMRIRDIVTVPPSVEQEQLSYIKQAIKKIEMLRYFVEFARDYGWVEWLEAEGKLQNLFRMTSHYDEVDELLAAWLVEQFLVSHQKELFQLIFKNHSKISPLLWKSICTYLKETKKPMDPILFAKWTLLLLETAENNSQSIEKISYLLQKCSFPEHKEISVLLLTFILDGKIKLKRVKRWEDDMQDSVELEESSCLPVSVFSHVQRIWEEKMKPHISYFAGPILVMGLEKLQMLSLRQTALQKRDGVLYHTMEFSEHDLQPKDFTFLIRIMKECLAYLCEHNKEKAAYYIAQMIDTDSILQKKIAIEAMSENTFVTADEKLMWLRKQQLIFDFTYKHEVFQFLKKHYQNALEKTKKEVIQEVMKHLENERFFDACLVLDLLYTCDANSTSTARAYRIMKRTHPHFTSNQYGEKKEEVRAPNIICDVTADGLLKLKGHEIKKQILLCSNDDSFEQRHFLEMLSKACKLNVDWSIALAYQLIGEQRVSDEIWFVCIREWRNNRKLTNEQIQKIIPLLQQFVRNPAFYWLISSFLYEISNRLEDFQENQIRAVKRFAFSLFPHIMKGESSFKVGELDFYNESIQHPVGKMTSVLLKLLAYDHLYDRNIHEYLFLFEEQIKVASERTHFMLARLTADVTFLFHIEKQWCRKYVLPYLKLNREHKAVKYAWAGLCYTQINLPLFTEIKKYIKYAAEHLELLHPHTKQVFLKWLSFVCIKCVLYWGQRTDWVYMIFIEEKEHDKIKFLKHLCYYVKTLSAREKQKFWDSWLATFLKERPKMSLITGREYVMLLRFVFYMDEVAEKGVYTILNCFPIPIEHCSEAEMKQLLLTILTRKEKVIAHVQAYAKLFFILLQIVQDASSIENEMIQMKEMLETCHVDDDILTAIQNEMIRIGIVVTNFQQES
>NC_009674.1|WP_012094479.1|2116890_2117967_-|bifunctional-3-deoxy-7-phosphoheptulonate-synthase/chorismate-mutase
MANHELEQLRKQVDEINLQLLKLLNERGRIVQKIGEQKQLQGTKRFDPVREREVLDMIAERNEGPFETSTVQHIFKTIFKASLELQEDDNRKALLVSRKKKQENTIVDVKGERLGSGTQSFIMGPCAVESLEQVRQVAQAIKEQGLKLMRGGAFKPRTSPYDFQGLGVEGLQILRQVADEFDLAIISEILNPNDVEMALDYVDVIQVGARNMQNFDLLRAVGKVNKPVLLKRGLAATIDEFMHAAEYIIAQGNDQIILCERGIRTYEKATRNTLDISAVPILKKETHLPVVVDVTHSTGRRDLLLPTAKAALAIGADAVMAEVHPDPAVALSDSAQQMDIPEFHRFMEELKEFKNKLS
>NC_009674.1|WP_012094478.1|2114858_2116484_-|ATP-binding-cassette-domain-containing-protein
MITVSNVSLRFADRKLFEDVNIKFTPGNCYGLIGANGAGKSTFLKILSGEIEPTTGDVHITPGERLAVLKQNHFEYEEFPVLETVIMGHTRLYEVMQEKNAIYMKEDFSDEDGMRAAELEGEFAELNGWEAESEAAILLKGLGIGEELHDKKMSELTGAEKVKVLLAQALFGQPDVLLLDEPTNHLDLKAIQWLENFLMNFENTVIVVSHDRHFLNKVCTHMADLDFGKIQLYVGNYDFWYESSQLALKLTQDANKKKEEKIKELQNFIARFSSNASKAKQATSRKKLLDKITLDDIKPSSRRYPFVGFTPEREVGNDLLTVEGLSKTIDGEKVLDNVYFTLNKGDKVAFIGRNDIAMTTLFKILMGEMEPDSGSFKWGVTTSQSYFPRDNSAYFENSEYNLVEWLRQFSPQDESESFLRGFLGRMLFSGEEVKKNVSVLSGGEKVRCMLSKMMLSGANVLVLDDPTNHLDLESITALNNGLIAFKGTILFTSHDHQFVQTIANRIIEVTPNGVIDKETTYDEYLENEELQKQVSAMYQNK
>NC_009674.1|WP_012094477.1|2112411_2114385_-|LTA-synthase-family-protein
MKQLLQKSKRVLSNHFGFFIFAVVLFWLKTYAAYVTEFNLGISNTIQKFLLFFNPLSSAILFLGLALFAKGKRSYILLIVINLLLSILLYANVVYYRFFSDFITFPTLTQTNNFGEIGGSVLALLQPYDPLYFLDTIVLLVLVLTKVANPKPIRVAKYKLSLVFISAILIFSINLGLAESDRPQLLTRTFDRNYIVKYLGAYNYTIYDGIQSMKASTERAMADGDSMTEVRNYIASNYASPSAEYFGKGKGMNVIYIHLESFQNFLIDYKLNGQEVTPFINSFTKDANTLYFDNFFHQTGQGKTSDAEFMLENSMFGLPQGSVFTTKSHNTYQAAPAILGQQGYTSAVFHGNYKTFWNRDDIYKSFGFNKFFDASYYDMNEKDVVNYGLKDKPFFNESIPLLETVKQPFYTKFITLSNHFPYPIDKEEATIEPATTGDSSVDTYFQTARYLDEAVKGFVDYLKQSGLYDNSIIVMYGDHYGISDNHNRAMSQIMGKEIHSFENAQLQRVPLIVRVPGIKGGVQHQYGGEIDVLPTLLHLLGIDTKDYIQFGTDLLSPEHKQVVAFRNGNYVSPTVTALNGRYYDTTTGEPVEVTEEIKQNEQMVQQTLKLSDQVVNGDLLRFYTPEGFTPVDRSKYNYNHRDKNKTKVKTTQDTKTE
>NC_009674.1|WP_012094476.1|2109670_2111776_-|transcription-antiterminator
MILDYRSAAILQQMMQADSYTSVDQLTEVLQVSKRTIYYDMKKVDDWLITEHLEPIQYVRPLGYCLDKKTKQKVAQKLQGLITVQYEYSPQERKAWLALYLLTEEKRILLEDLIKLIQVSRNTTLADLKKLKAELGKFKLSLQFHRKQGYYIKGMEQGKRNVLIAYLSQLIAKHGWEYVVSHMRNIVNHGEGEKKQTAQDKLHVIKGILSKCEEFLGVQYTDEVLENLSVYMYLFCSRIVKGRYIEMEETEKAVLRETKHFQAATYIGTQFEKLLYIKFPKDEIYYITTHLLGAKVNAQQKEYEKNDVHGIWHIVDCMIQDFQHYACVIFRDFTGLASDLYLHMKPAFYRVKYGIEIKNPLLQIIRNSYAEVYHLTKKVVHHFEQYVGKEISEDEIAFITMHFSAWMRKEGIVPSPRKTALLVCPNGIGTSRMLQYQLEQLFSNMDILQAISKREYESNTFDVDCIITTTELEKGLIPIFMVNPILTDAEKASLFRKVNATLFREDQNDSADIIMQMIHKYADVRDEHALKRELREFISGPVHFGREEKYKPMLNELLTKEYIQLQDHVDSWEGAIRIAAKPLLQTEYISEEYVQEMIANVKKLGPYIVIAPKIAIPHARPESGVKKLGMSLLQLKESVSFSEKQEHAVNLIIVLAAIDNETHLKALAQLSDMLSQPENVDLLIRSNSKEQMLEMIAKYSN
>NC_009674.1|WP_012094486.1|2126608_2126872_-|CRISPR-associated-endonuclease-Cas2
MFVIITYDIGEKRVGKACKKLKQYLTWTQNSVFEGELSRTQLLKCLAELDQIIISSEDSIYLYEVNNPRNIKKKVFGIEKSYEELFL
>NC_009674.1|WP_012094487.1|2127852_2128350_-|CRISPR-associated-protein-Cas4
MKGTYIHYYFVCHRKLWLFVHQIQLEKESERVIEGKILHDSTYQRMEHRELDIDGVGKIDEIEGEYIREIKLTSKMQEADRWQLLYYLAELKKRGVTKKGLLSYKKEKRTEEVHLTEANQQELENIQKRIQAIILSDKPPKLEKKKYCSSCAYYDFCFSGEGEGC
>NC_009674.1|WP_109456139.1|2128412_2130647_-|CRISPR-associated-helicase-Cas3'
MMMMFLAKSNPKETLREHTDELRSRYKKLKESYGHYFDERIWELLLYAVDYHDAGKAHEPFQLNIRRALGEGVKLQRNLEVPHNYLSPFLLPESIFSLPKKDYQALIQAIAYHHERDIEPNDTLIRQALWQDLWPKMDEINKHLNINGANLEKKFNRILAQLHRRIKYSDNKENYVDYVILKGLLHRIDHAASAHVDIEIDAKQDFKKLVDAGFQKIAEKKRVPVEEVYRDLQKHAHKHRKENLIIVAQTGMGKTEAALLWASDSKTFFTLPLRVSINALFHRVYEKMNYKNVGLLHSSSMDYLTENLEEDWEVIAEQSKHFSSKLLFTTIDQILKFPFLYRGYEKELATMAYSSVVIDEIQAYDPKIAAVLVRALEMIYLVGGKFLLMTATLPSIYLETLNESDIISSDGFRVDTFIDDCVIRHCIEVVEKPIVDDFEKIVDLGKQKKILVIANTVKRAMELYNKIKEYSDNVHVFHSMYIQKHRTLIEKELLLFDENKEATGIWITTQLVEASIDIDFDVLFTEAATLDSLCQRFGRCYRRRQYMMHQEPNVFIYAVDMSGVKYVYDEEILMKSLDILRPFNRKILLESQKIELVSQLYSRENLKGTEFLKTFDDALEQLQTFEDYTLSSKDAQKLLRDIQAELVIPRNIYDENEHLFEQLKIVNKEERARLYREIAKLTVSLRKNRVRGKTSRIPHERIQSNGKKYNLLPWIKILELQYDFDEKSKTGTGVLLDQELDNFI
>NC_009674.1|WP_012094490.1|2130691_2131390_-|type-I-B-CRISPR-associated-protein-Cas5
MKVIRLKLFQETACYTKPFANKVAETYPLPPYSTVKGMIHQLLQANELLPLRFSIQGNYETKLIDYRKSYMVKKKSVSMPIIFDGLAMEVPEQEHMTSMPLYTHMLFNVELVIHIAGEEALLERIYQHFIELNQHLSLGRHEDLVRVDEVTFVELEECDEWYSKYAIYVPKYYYKTDFPAGIPYRLNWTYKIVNGIREWNKIPSLYVNGNNPHFEDGKLFHTDGEHIVLWNE
>NC_009674.1|WP_012094491.1|2131386_2132280_-|type-I-B-CRISPR-associated-protein-Cas7/Cst2/DevR
MNNKALTLTIIFKASSLNYGEGTANISELKKFHRGNGEVYSFASRQAIRYDIVRLGNQLFNWNLNVVDKSKGVVQFKDDCTIADSVEMDLFGYMKTKAKAGADKRSAVVRLSHAVSLEPYRSDLEFLNNMGLASRIQENPNLATLEQHESLYTYTLTVDLSKVGVDGEIELPVDEKVNRVKQLIELTKYLNREIRGRQENLSPLFVIGGVYPIANPFFLGRISLQNFDSNLLNVKSLASVLGQTVLGHDVRTCTKIGLVDGVFANEEEISQLTDTVSVEEFYQHVMNEVEQFYKVLV
>NC_009674.1|WP_012094492.1|2132272_2134021_-|type-I-B-CRISPR-associated-protein-Cas8b1/Cst1
MIFVTEEIPLAAEEWTITQGLVGYYRILKHAGIKVKTTDEGILFNPEHLRNFEHYYFDYFLDRFSVAKRDEQNIRRTFLKFRAESESKGSKEAKRRMQAAKKSLDETIKKTAIEKVEKKFEDSSHKKRLVEYATLIRNQKTYNPEMDKWIEEYIQALSEPNINEKLTLNYFKATVLGTYFGQVSFLNVSHTSKDIEEQKEIFRKDYIESLLADLELQQMIARAEDSDEIMKYLEISTHEMAKKLKTKFKKMTIQQIKDYVSNEINCCSFFDSQWAFEQYSELHFSPLSMSASKALNFYWNANGTLTIPVSKLAKLILFCAPAGASIIGGKSLFVQREGRFEQVIYANETYEIGRSKDKAFDEIIFDLIAEQKTKAQHTGDSYLILEYSSEYNAKKTDLQYLHLTPGLCSFFKEKNCTKWFSRLNYVLRNQIVHAFLRYQDSKHIIHNALRKKLQEQKLANEIVYACLLRCYYLFFVKGEGKMNTDLKTSKNRIWSAFYEGVAIKNIVEEGKIRSVAYRLLNAIRSNDKKMFLDTVMRLYMSVEKPFPRVFMNILDESNIDFASIGDSFIAGLISKEEEKINE
>NC_009674.1|WP_012094493.1|2134020_2134722_-|CRISPR-associated-endoribonuclease-Cas6
MRLHIKLQTNRFPISYRMMMVSFIKEALKLSDAAYFQQIYQESKANRPFSYGVYIHDYKLNATEFHIKGYVGLTITSPDAQFMLHFYNGLMKMNDFRYKGFSLKRMKVQMVNSADINQNHVYFKTLSPLLIRDKHAKPIFIDDDKFEKELNYISDTVLKEFRGYGLKQPLIFTSKNMKKVVVKEKIHSDHDTLFFTGYHGIFSLQGAVEDLKILSEIGLGFRSSQGFGAVEVV
>NC_009674.1|WP_012094494.1|2136507_2136834_-|antibiotic-biosynthesis-monooxygenase
MFIETKTLTVKEGTSDLVVQRFSGEGMIEKFEGFIDLNVLVKKVRRGDEEVVIMIRWESEEAWKNWETSEEHLAGHRANRGKPKPEHILNAEHAVYYVKATKSAYQQS
>NC_009674.1|WP_012094495.1|2137175_2137520_+|hypothetical-protein
MRKAILIFIVAIFIIGIVHIAVTPINYKSYTIEALWFASAGCTLIFLAFLNYVLISIKQRQTRFFVICHTANILCTILVAFILTIAFAPHIILLFVLLVSKTLLVIGFQFSSKS
>NC_009674.1|WP_012094496.1|2137758_2137974_-|uridine-kinase
MSFNQVLKVIDENIGKRFVLGIDGLSRLGKTTLVKQLEQKLKQKGASFYIFHIDDHIVERNKRYHTKFEEW

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Crispr_ID: NC_009674_3

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_009674_3

2135668-2136221

Unclear

I-A

Consensus_repeat	Method
CTTTATATCCCACTACGTTCAGATAAAAC	CRISPRCasFinder
CTTTATATCCCACTACGTTCAGATAAAAC	CRT
CTTTATATCCCACTACGTTCAGATAAAAC	PILER-CR

8 spacers

cas6,cas8b2,cas7,cas5,cas3,cas4,cas2

The CRISPR arrays of NC_009674_3

>merge|NC_009674|3|2135668-2136221|CRISPRCasFinder,CRT,PILER-CR
TTATCTTATCCACTACGTTCAGATAAAACTTTCTAACAATGTCCAAAAACCATTGAATACATTGGATTTATATCCCACTACGTTCAGATAAAACTGGGACAAACATGCTACTTTCTTGAACGCTCAGTCAACTTTATATCCCACTACGTTCAGATAAAACAGGATTTCACGGAGCGATTGCAAAGAAAAACATCCCCTTTATATCCCACTACGTTCAGATAAAACCCGTGTTGGTGGCGTTGGTGGTGCATTGCAAACCGTCTTTATATCCCACTACGTTCAGATAAAACCACTGAAATTAGTGTCGTCTAAAACAGAGACGTTTCCCTTTATATCCCACTACGTTCAGATAAAACTGAACCATTTTTCAATAATCAATATTCCTTTCTTAAGCTTTATATCCCACTACGTTCAGATAAAACTCGTGCGACCAAGCGGAAATGGTAGCGCACGGATCACTTTATATCCCACTACGTTCAGATAAAACACGCGCGTAGTGTAGAAGACTTTGCACGCGGTATCGTGCTTTATATCCCACTACGTTCAGATAAAAC

>NC_009674|3|3|2135668-2136221|CRISPRCasFinder
TTATCTTATCCACTACGTTCAGATAAAAC	TTTCTAACAATGTCCAAAAACCATTGAATACATTGG
ATTTATATCCCACTACGTTCAGATAAAAC	TGGGACAAACATGCTACTTTCTTGAACGCTCAGTCAA
CTTTATATCCCACTACGTTCAGATAAAAC	AGGATTTCACGGAGCGATTGCAAAGAAAAACATCCC
CTTTATATCCCACTACGTTCAGATAAAAC	CCGTGTTGGTGGCGTTGGTGGTGCATTGCAAACCGT
CTTTATATCCCACTACGTTCAGATAAAAC	CACTGAAATTAGTGTCGTCTAAAACAGAGACGTTTCC
CTTTATATCCCACTACGTTCAGATAAAAC	TGAACCATTTTTCAATAATCAATATTCCTTTCTTAAG
CTTTATATCCCACTACGTTCAGATAAAAC	TCGTGCGACCAAGCGGAAATGGTAGCGCACGGATCA
CTTTATATCCCACTACGTTCAGATAAAAC	ACGCGCGTAGTGTAGAAGACTTTGCACGCGGTATCGTG
CTTTATATCCCACTACGTTCAGATAAAAC

>NC_009674|3|2|2135668-2136221|CRT
TTATCTTATCCACTACGTTCAGATAAAAC	TTTCTAACAATGTCCAAAAACCATTGAATACATTGG
ATTTATATCCCACTACGTTCAGATAAAAC	TGGGACAAACATGCTACTTTCTTGAACGCTCAGTCAA
CTTTATATCCCACTACGTTCAGATAAAAC	AGGATTTCACGGAGCGATTGCAAAGAAAAACATCCC
CTTTATATCCCACTACGTTCAGATAAAAC	CCGTGTTGGTGGCGTTGGTGGTGCATTGCAAACCGT
CTTTATATCCCACTACGTTCAGATAAAAC	CACTGAAATTAGTGTCGTCTAAAACAGAGACGTTTCC
CTTTATATCCCACTACGTTCAGATAAAAC	TGAACCATTTTTCAATAATCAATATTCCTTTCTTAAG
CTTTATATCCCACTACGTTCAGATAAAAC	TCGTGCGACCAAGCGGAAATGGTAGCGCACGGATCA
CTTTATATCCCACTACGTTCAGATAAAAC	ACGCGCGTAGTGTAGAAGACTTTGCACGCGGTATCGTG
CTTTATATCCCACTACGTTCAGATAAAAC

>NC_009674|3|2|2135734-2136221|PILER-CR
TTTATATCCCACTACGTTCAGATAAAACT	GGGACAAACATGCTACTTTCTTGAACGCTCAGTCAAC
TTTATATCCCACTACGTTCAGATAAAACA	GGATTTCACGGAGCGATTGCAAAGAAAAACATCCCC
TTTATATCCCACTACGTTCAGATAAAACC	CGTGTTGGTGGCGTTGGTGGTGCATTGCAAACCGTC
TTTATATCCCACTACGTTCAGATAAAACC	ACTGAAATTAGTGTCGTCTAAAACAGAGACGTTTCCC
TTTATATCCCACTACGTTCAGATAAAACT	GAACCATTTTTCAATAATCAATATTCCTTTCTTAAGC
TTTATATCCCACTACGTTCAGATAAAACT	CGTGCGACCAAGCGGAAATGGTAGCGCACGGATCAC
TTTATATCCCACTACGTTCAGATAAAACA	CGCGCGTAGTGTAGAAGACTTTGCACGCGGTATCGTGC
TTTATATCCCACTACGTTCAGATAAAAC

Protein	Signature genes	Signature genes Name	Protein_function
NC_009674.1\|WP_012094487.1\|2127852_2128350_-\|CRISPR-associated-protein-Cas4	cas4	pfam01930_cas4_CAS-I	gnl\|CDD\|366863
NC_009674.1\|WP_041809787.1\|2124544_2124925_-\|VOC-family-protein	unknown	unknown	gnl\|CDD\|319924
NC_009674.1\|WP_012094494.1\|2136507_2136834_-\|antibiotic-biosynthesis-monooxygenase	unknown	unknown	gnl\|CDD\|225209
NC_009674.1\|WP_012094493.1\|2134020_2134722_-\|CRISPR-associated-endoribonuclease-Cas6	cas6	pfam01881_cas6_CAS-I:CAS-III	gnl\|CDD\|187783
NC_009674.1\|WP_012094492.1\|2132272_2134021_-\|type-I-B-CRISPR-associated-protein-Cas8b1/Cst1	cas8b2	cd09665_cas8b2_CAS-I-B	gnl\|CDD\|187796
NC_009674.1\|WP_109090138.1\|2125162_2125336_-\|DUF2332-family-protein	unknown	unknown	gnl\|CDD\|378386
NC_009674.1\|WP_012094490.1\|2130691_2131390_-\|type-I-B-CRISPR-associated-protein-Cas5	cas5	cd09658_cas5_CAS-I-B	gnl\|CDD\|187789
NC_009674.1\|WP_012094485.1\|2125653_2125800_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|376564
NC_009674.1\|WP_012094491.1\|2131386_2132280_-\|type-I-B-CRISPR-associated-protein-Cas7/Cst2/DevR	cas7	cd09687_cas7_CAS-I-B	gnl\|CDD\|187818
NC_009674.1\|WP_012094498.1\|2138888_2139134_+\|hypothetical-protein	unknown	unknown	unknown
NC_009674.1\|WP_012094499.1\|2139371_2139908_-\|DUF2812-domain-containing-protein	unknown	unknown	gnl\|CDD\|378589
NC_009674.1\|WP_012094495.1\|2137175_2137520_+\|hypothetical-protein	unknown	unknown	unknown
NC_009674.1\|WP_012094486.1\|2126608_2126872_-\|CRISPR-associated-endonuclease-Cas2	cas2	cd09725_cas2_CAS-I:CAS-II:CAS-III:CAS-V	gnl\|CDD\|187856
NC_009674.1\|WP_109456139.1\|2128412_2130647_-\|CRISPR-associated-helicase-Cas3'	cas3	COG1203_cas3_CAS-I	gnl\|CDD\|273707
NC_009674.1\|WP_012094502.1\|2141898_2142366_-\|NUDIX-hydrolase	unknown	unknown	gnl\|CDD\|240044
NC_009674.1\|WP_012094500.1\|2139909_2140233_-\|helix-turn-helix-transcriptional-regulator	unknown	unknown	gnl\|CDD\|163261
NC_009674.1\|WP_012094497.1\|2137952_2138519_-\|GNAT-family-N-acetyltransferase	unknown	unknown	gnl\|CDD\|224584
NC_009674.1\|WP_012094504.1\|2143099_2144140_-\|SDR-family-oxidoreductase	unknown	unknown	gnl\|CDD\|187575
NC_009674.1\|WP_012094496.1\|2137758_2137974_-\|uridine-kinase	unknown	unknown	gnl\|CDD\|169051
NC_009674.1\|WP_012094501.1\|2140834_2141818_-\|DUF4003-domain-containing-protein	unknown	unknown	gnl\|CDD\|379047

Protein	Function_ID	Function_description	E-value
NC_009674.1\|WP_012094487.1\|2127852_2128350_-\|CRISPR-associated-protein-Cas4	gnl\|CDD\|366863	pfam01930, Cas_Cas4, Domain of unknown function DUF83. This domain has no known function. The domain contains three conserved cysteines at its C-terminus.	3.71199e-58
NC_009674.1\|WP_041809787.1\|2124544_2124925_-\|VOC-family-protein	gnl\|CDD\|319924	cd07263, VOC_like, uncharacterized subfamily of vicinal oxygen chelate (VOC) family. The vicinal oxygen chelate (VOC) superfamily is composed of structurally related proteins with paired beta.alpha.beta.beta.beta motifs that provide a metal coordination environment with two or three open or readily accessible coordination sites to promote direct electrophilic participation of the metal ion in catalysis. VOC domain is found in a variety of structurally related metalloproteins, including the bleomycin resistance protein, glyoxalase I, and type I ring-cleaving dioxygenases. A bound metal ion is required for protein activities for the members of this superfamily. A variety of metal ions have been found in the catalytic centers of these proteins including Fe(II), Mn(II), Zn(II), Ni(II) and Mg(II). The protein superfamily contains members with or without domain swapping. The proteins of this family share three conserved metal binding amino acids with the type I extradiol dioxygenases, which shows no domain swapping.	1.49534e-44
NC_009674.1\|WP_012094494.1\|2136507_2136834_-\|antibiotic-biosynthesis-monooxygenase	gnl\|CDD\|225209	COG2329, COG2329, Uncharacterized enzyme involved in biosynthesis of extracellular polysaccharides [General function prediction only].	5.76195e-19
NC_009674.1\|WP_012094493.1\|2134020_2134722_-\|CRISPR-associated-endoribonuclease-Cas6	gnl\|CDD\|187783	cd09652, Cas6-I-III, CRISPR/Cas system-associated RAMP superfamily protein Cas6. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas6 is an endoribonuclease that generates crRNAs, predicted subunit of Cascade complex; RAMP superfamily protein; Possesses double RRM/ferredoxin fold.	1.0641e-22
NC_009674.1\|WP_012094492.1\|2132272_2134021_-\|type-I-B-CRISPR-associated-protein-Cas8b1/Cst1	gnl\|CDD\|187796	cd09665, Cas8a1_I-A, CRISPR/Cas system-associated protein Cas8a1. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Large proteins, some contain Zn-finger domain; signature gene for I-A subtype; also known as CXXC_CXXC family.	1.471e-10
NC_009674.1\|WP_109090138.1\|2125162_2125336_-\|DUF2332-family-protein	gnl\|CDD\|378386	pfam10094, DUF2332, Uncharacterized protein conserved in bacteria (DUF2332). Members of this family of hypothetical bacterial proteins have no known function.	1.71552e-08
NC_009674.1\|WP_012094490.1\|2130691_2131390_-\|type-I-B-CRISPR-associated-protein-Cas5	gnl\|CDD\|187789	cd09658, Cas5_I-B, CRISPR/Cas system-associated RAMP superfamily protein Cas5. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas5 is a RAMP superfamily protein; Subunit of the Cascade complex.	2.84624e-29
NC_009674.1\|WP_012094485.1\|2125653_2125800_-\|hypothetical-protein	gnl\|CDD\|376564	pfam01548, DEDD_Tnp_IS110, Transposase. Transposase proteins are necessary for efficient DNA transposition. This family includes an amino-terminal region of the pilin gene inverting protein (PIVML) and of members of the IS111A/IS1328/IS1533 family of transposases. The C-terminus is represented by family pfam02371.	0.00255682
NC_009674.1\|WP_012094491.1\|2131386_2132280_-\|type-I-B-CRISPR-associated-protein-Cas7/Cst2/DevR	gnl\|CDD\|187818	cd09687, Cas7_I-C, CRISPR/Cas system-associated RAMP superfamily protein Cas7. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas7 is a RAMP superfamily protein; Subunit of the Cascade complex; also known as Cst2/DevR family.	4.74396e-53
NC_009674.1\|WP_012094500.1\|2139909_2140233_-\|helix-turn-helix-transcriptional-regulator	gnl\|CDD\|163261	TIGR03433, padR_acidobact, transcriptional regulator, Acidobacterial, PadR-family. Members of this protein family are putative transcriptional regulators of the PadR family, as found in species of the Acidobacteria. This family of proteins has expanded greatly in this lineage, and where it regularly is found in the vicinity of a putative transporter protein [Regulatory functions, DNA interactions].	5.02854e-08
NC_009674.1\|WP_012094499.1\|2139371_2139908_-\|DUF2812-domain-containing-protein	gnl\|CDD\|378589	pfam11193, DUF2812, Protein of unknown function (DUF2812). This is a bacterial family of uncharacterized proteins, however some members of this family are annotated as membrane proteins.	5.25447e-33
NC_009674.1\|WP_012094496.1\|2137758_2137974_-\|uridine-kinase	gnl\|CDD\|169051	PRK07667, PRK07667, uridine kinase; Provisional.	8.82097e-32
NC_009674.1\|WP_012094486.1\|2126608_2126872_-\|CRISPR-associated-endonuclease-Cas2	gnl\|CDD\|187856	cd09725, Cas2_I_II_III, CRISPR/Cas system-associated protein Cas2. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas2 is present in majority of CRISPR/Cas systems along with Cas1; RNAse specific to U-rich regions; Possesses an RRM/ferredoxin fold.	2.02502e-27
NC_009674.1\|WP_109456139.1\|2128412_2130647_-\|CRISPR-associated-helicase-Cas3'	gnl\|CDD\|273707	TIGR01587, CRISPR-associated_endonuclease/helicase_Cas3, CRISPR-associated helicase Cas3. This model represents the highly conserved core region of an alignment of Cas3, a protein found in association with CRISPR repeat elements in a broad range of bacteria and archaea. Cas3 appears to be a helicase, with regions found by pfam00270 (DEAD/DEAH box helicase) and pfam00271 (Helicase conserved C-terminal domain). Some but not all members have an N-terminal HD domain region (pfam01966) that is not included within this model.	8.75921e-63
NC_009674.1\|WP_012094502.1\|2141898_2142366_-\|NUDIX-hydrolase	gnl\|CDD\|240044	cd04688, Nudix_Hydrolase_29, Members of the Nudix hydrolase superfamily catalyze the hydrolysis of NUcleoside DIphosphates linked to other moieties, X. Enzymes belonging to this superfamily require a divalent cation, such as Mg2+ or Mn2+, for their activity and contain a highly conserved 23-residue nudix motif (GX5EX7REUXEEXGU, where U = I, L or V), which functions as a metal binding and catalytic site. Substrates of nudix hydrolases include intact and oxidatively damaged nucleoside triphosphates, dinucleoside polyphosphates, nucleotide-sugars and dinucleotide enzymes. These substrates are metabolites or cell signaling molecules that require regulation during different stages of the cell cycle or during periods of stress. In general, the role of the nudix hydrolase is to sanitize the nucleotide pools and to maintain cell viability, thereby serving as surveillance & "house-cleaning" enzymes. Substrate specificity is used to define families within the superfamily. Differences in substrate specificity are determined by the N-terminal extension or by residues in variable loop regions. Mechanistically, substrate hydrolysis occurs by a nucleophilic substitution reaction, with variation in the numbers and roles of divalent cations required.	9.11694e-49
NC_009674.1\|WP_012094497.1\|2137952_2138519_-\|GNAT-family-N-acetyltransferase	gnl\|CDD\|224584	COG1670, RimL, Acetyltransferases, including N-acetylases of ribosomal proteins [Translation, ribosomal structure and biogenesis].	1.23367e-45
NC_009674.1\|WP_012094504.1\|2143099_2144140_-\|SDR-family-oxidoreductase	gnl\|CDD\|187575	cd05265, SDR_a1, atypical (a) SDRs, subgroup 1. Atypical SDRs in this subgroup are poorly defined and have been identified putatively as isoflavones reductase, sugar dehydratase, mRNA binding protein etc. Atypical SDRs are distinct from classical SDRs. Members of this subgroup retain the canonical active site triad (though not the upstream Asn found in most SDRs) but have an unusual putative glycine-rich NAD(P)-binding motif, GGXXXXG, in the usual location. Atypical SDRs generally lack the catalytic residues characteristic of the SDRs, and their glycine-rich NAD(P)-binding motif is often different from the forms normally seen in classical or extended SDRs. Atypical SDRs include biliverdin IX beta reductase (BVR-B,aka flavin reductase), NMRa (a negative transcriptional regulator of various fungi), progesterone 5-beta-reductase like proteins, phenylcoumaran benzylic ether and pinoresinol-lariciresinol reductases, phenylpropene synthases, eugenol synthase, triphenylmethane reductase, isoflavone reductases, and others. SDRs are a functionally diverse family of oxidoreductases that have a single domain with a structurally conserved Rossmann fold, an NAD(P)(H)-binding region, and a structurally diverse C-terminal region. Sequence identity between different SDR enzymes is typically in the 15-30% range; they catalyze a wide range of activities including the metabolism of steroids, cofactors, carbohydrates, lipids, aromatic compounds, and amino acids, and act in redox sensing. Classical SDRs have an TGXXX[AG]XG cofactor binding motif and a YXXXK active site motif, with the Tyr residue of the active site motif serving as a critical catalytic residue (Tyr-151, human 15-hydroxyprostaglandin dehydrogenase numbering). In addition to the Tyr and Lys, there is often an upstream Ser and/or an Asn, contributing to the active site; while substrate binding is in the C-terminal region, which determines specificity. The standard reaction mechanism is a 4-pro-S hydride transfer and proton relay involving the conserved Tyr and Lys, a water molecule stabilized by Asn, and nicotinamide. In addition to the Rossmann fold core region typical of all SDRs, extended SDRs have a less conserved C-terminal extension of approximately 100 amino acids, and typically have a TGXXGXXG cofactor binding motif. Complex (multidomain) SDRs such as ketoreductase domains of fatty acid synthase have a GGXGXXG NAD(P)-binding motif and an altered active site motif (YXXXN). Fungal type ketoacyl reductases have a TGXXXGX(1-2)G NAD(P)-binding motif.	4.42697e-86
NC_009674.1\|WP_012094501.1\|2140834_2141818_-\|DUF4003-domain-containing-protein	gnl\|CDD\|379047	pfam13170, DUF4003, Protein of unknown function (DUF4003). This family of proteins is functionally uncharacterized. This family of proteins is found in bacteria. Proteins in this family are typically between 327 and 345 amino acids in length.	1.01847e-102

>NC_009674.1|WP_012094493.1|2134020_2134722_-|CRISPR-associated-endoribonuclease-Cas6
MRLHIKLQTNRFPISYRMMMVSFIKEALKLSDAAYFQQIYQESKANRPFSYGVYIHDYKLNATEFHIKGYVGLTITSPDAQFMLHFYNGLMKMNDFRYKGFSLKRMKVQMVNSADINQNHVYFKTLSPLLIRDKHAKPIFIDDDKFEKELNYISDTVLKEFRGYGLKQPLIFTSKNMKKVVVKEKIHSDHDTLFFTGYHGIFSLQGAVEDLKILSEIGLGFRSSQGFGAVEVV
>NC_009674.1|WP_012094492.1|2132272_2134021_-|type-I-B-CRISPR-associated-protein-Cas8b1/Cst1
MIFVTEEIPLAAEEWTITQGLVGYYRILKHAGIKVKTTDEGILFNPEHLRNFEHYYFDYFLDRFSVAKRDEQNIRRTFLKFRAESESKGSKEAKRRMQAAKKSLDETIKKTAIEKVEKKFEDSSHKKRLVEYATLIRNQKTYNPEMDKWIEEYIQALSEPNINEKLTLNYFKATVLGTYFGQVSFLNVSHTSKDIEEQKEIFRKDYIESLLADLELQQMIARAEDSDEIMKYLEISTHEMAKKLKTKFKKMTIQQIKDYVSNEINCCSFFDSQWAFEQYSELHFSPLSMSASKALNFYWNANGTLTIPVSKLAKLILFCAPAGASIIGGKSLFVQREGRFEQVIYANETYEIGRSKDKAFDEIIFDLIAEQKTKAQHTGDSYLILEYSSEYNAKKTDLQYLHLTPGLCSFFKEKNCTKWFSRLNYVLRNQIVHAFLRYQDSKHIIHNALRKKLQEQKLANEIVYACLLRCYYLFFVKGEGKMNTDLKTSKNRIWSAFYEGVAIKNIVEEGKIRSVAYRLLNAIRSNDKKMFLDTVMRLYMSVEKPFPRVFMNILDESNIDFASIGDSFIAGLISKEEEKINE
>NC_009674.1|WP_012094491.1|2131386_2132280_-|type-I-B-CRISPR-associated-protein-Cas7/Cst2/DevR
MNNKALTLTIIFKASSLNYGEGTANISELKKFHRGNGEVYSFASRQAIRYDIVRLGNQLFNWNLNVVDKSKGVVQFKDDCTIADSVEMDLFGYMKTKAKAGADKRSAVVRLSHAVSLEPYRSDLEFLNNMGLASRIQENPNLATLEQHESLYTYTLTVDLSKVGVDGEIELPVDEKVNRVKQLIELTKYLNREIRGRQENLSPLFVIGGVYPIANPFFLGRISLQNFDSNLLNVKSLASVLGQTVLGHDVRTCTKIGLVDGVFANEEEISQLTDTVSVEEFYQHVMNEVEQFYKVLV
>NC_009674.1|WP_012094490.1|2130691_2131390_-|type-I-B-CRISPR-associated-protein-Cas5
MKVIRLKLFQETACYTKPFANKVAETYPLPPYSTVKGMIHQLLQANELLPLRFSIQGNYETKLIDYRKSYMVKKKSVSMPIIFDGLAMEVPEQEHMTSMPLYTHMLFNVELVIHIAGEEALLERIYQHFIELNQHLSLGRHEDLVRVDEVTFVELEECDEWYSKYAIYVPKYYYKTDFPAGIPYRLNWTYKIVNGIREWNKIPSLYVNGNNPHFEDGKLFHTDGEHIVLWNE
>NC_009674.1|WP_109456139.1|2128412_2130647_-|CRISPR-associated-helicase-Cas3'
MMMMFLAKSNPKETLREHTDELRSRYKKLKESYGHYFDERIWELLLYAVDYHDAGKAHEPFQLNIRRALGEGVKLQRNLEVPHNYLSPFLLPESIFSLPKKDYQALIQAIAYHHERDIEPNDTLIRQALWQDLWPKMDEINKHLNINGANLEKKFNRILAQLHRRIKYSDNKENYVDYVILKGLLHRIDHAASAHVDIEIDAKQDFKKLVDAGFQKIAEKKRVPVEEVYRDLQKHAHKHRKENLIIVAQTGMGKTEAALLWASDSKTFFTLPLRVSINALFHRVYEKMNYKNVGLLHSSSMDYLTENLEEDWEVIAEQSKHFSSKLLFTTIDQILKFPFLYRGYEKELATMAYSSVVIDEIQAYDPKIAAVLVRALEMIYLVGGKFLLMTATLPSIYLETLNESDIISSDGFRVDTFIDDCVIRHCIEVVEKPIVDDFEKIVDLGKQKKILVIANTVKRAMELYNKIKEYSDNVHVFHSMYIQKHRTLIEKELLLFDENKEATGIWITTQLVEASIDIDFDVLFTEAATLDSLCQRFGRCYRRRQYMMHQEPNVFIYAVDMSGVKYVYDEEILMKSLDILRPFNRKILLESQKIELVSQLYSRENLKGTEFLKTFDDALEQLQTFEDYTLSSKDAQKLLRDIQAELVIPRNIYDENEHLFEQLKIVNKEERARLYREIAKLTVSLRKNRVRGKTSRIPHERIQSNGKKYNLLPWIKILELQYDFDEKSKTGTGVLLDQELDNFI
>NC_009674.1|WP_012094487.1|2127852_2128350_-|CRISPR-associated-protein-Cas4
MKGTYIHYYFVCHRKLWLFVHQIQLEKESERVIEGKILHDSTYQRMEHRELDIDGVGKIDEIEGEYIREIKLTSKMQEADRWQLLYYLAELKKRGVTKKGLLSYKKEKRTEEVHLTEANQQELENIQKRIQAIILSDKPPKLEKKKYCSSCAYYDFCFSGEGEGC
>NC_009674.1|WP_012094486.1|2126608_2126872_-|CRISPR-associated-endonuclease-Cas2
MFVIITYDIGEKRVGKACKKLKQYLTWTQNSVFEGELSRTQLLKCLAELDQIIISSEDSIYLYEVNNPRNIKKKVFGIEKSYEELFL
>NC_009674.1|WP_012094485.1|2125653_2125800_-|hypothetical-protein
MKDTTKYVGLDVSKEKIAVAIADEGREEPRYLGMIPHTPESLRKLIKN
>NC_009674.1|WP_109090138.1|2125162_2125336_-|DUF2332-family-protein
MGKDLKVSFISVKLIEGDRVALLAEIVEKIPKEFAICIFHTHVAKQMSESVKHGLIE
>NC_009674.1|WP_041809787.1|2124544_2124925_-|VOC-family-protein
MIHKVGQIMLYVKDQDEAVQFWTEKMGFHLIAEEDNGKGFRWIEIAPTKEAETSIVLHNKEFIAKMQPELNLNTPSMLFFTENIEQLHKQLVDKKVEVGEIVNMPTGKAFNFADDEGNYFAIMEKS
>NC_009674.1|WP_012094494.1|2136507_2136834_-|antibiotic-biosynthesis-monooxygenase
MFIETKTLTVKEGTSDLVVQRFSGEGMIEKFEGFIDLNVLVKKVRRGDEEVVIMIRWESEEAWKNWETSEEHLAGHRANRGKPKPEHILNAEHAVYYVKATKSAYQQS
>NC_009674.1|WP_012094495.1|2137175_2137520_+|hypothetical-protein
MRKAILIFIVAIFIIGIVHIAVTPINYKSYTIEALWFASAGCTLIFLAFLNYVLISIKQRQTRFFVICHTANILCTILVAFILTIAFAPHIILLFVLLVSKTLLVIGFQFSSKS
>NC_009674.1|WP_012094496.1|2137758_2137974_-|uridine-kinase
MSFNQVLKVIDENIGKRFVLGIDGLSRLGKTTLVKQLEQKLKQKGASFYIFHIDDHIVERNKRYHTKFEEW
>NC_009674.1|WP_012094497.1|2137952_2138519_-|GNAT-family-N-acetyltransferase
MGFPTLETERFILRELTLLDAENMFHYFQKESVMRYFGMDAIRNMEQVKRMIQMFSKKYKEGSQVRWGIELKGTNRFIGTCGFHFINLNHKRAEIGYELDDAYWGKGYATEAVQTIVTYAFQTMKLIRIGAVVYKENEASHKLLKKIGFQKEGLLRKYMIQNNVEYDTIIYSLLAEDWEKRSCLSIKY
>NC_009674.1|WP_012094498.1|2138888_2139134_+|hypothetical-protein
MEPMLCPNCKTNRTRFNILEQQVKPVKLNPQTGQIEEEYTNETLNVFHMSYQGPTYRVQCAVCGLVENPEQFIKPAQNKLF
>NC_009674.1|WP_012094499.1|2139371_2139908_-|DUF2812-domain-containing-protein
MEIKKTFKFFTAWNLEKEEAYLREMHQKGWAFQKYHFMYTFKKTEPKDVVYKADFNFDFQKSLKNQREYLEIYEMSGWKYVSSFTKWHYFCKEVVDKNELPDIYSETETRIEKLKDLLNHLVIIFLSILPAISISCLESPANKLSIIIKGFIGFVVCIHMYMFVRLILKIRKLKKEII
>NC_009674.1|WP_012094500.1|2139909_2140233_-|helix-turn-helix-transcriptional-regulator
MDEKAKKYIPLTEATYYILLSFAKRIHGYGVMQMVEEMTDGEVKLGPGTLYGNITKLLTEKLIVEVDSTDRKKCYMLTPFGREVLELEFKRLQRSVQNGKQILREKM
>NC_009674.1|WP_012094501.1|2140834_2141818_-|DUF4003-domain-containing-protein
MITLQQKLEQYTSIYKQLKRELKWKTSDSRTGMMIAAMYTSSDKPFDLERFLQISHYIKSQVGMFSYLKSYHRFVVAATLDIHFTHYKTAFQQFLDLYERFIASGFSRSIFTYLAAATLLPDDREQYEARIQRSVKVYKRMKEDHFFLTSTSDYPLAVLLAGQQEEIGPLMDRVERLYQKLATSGLRKGNALQFLSHILSLKKDIREDMLVARCTNIWNLFKQEKVKVKQMHYPAIGLLALLEDGEKEVSSIRTFMEKLQGDKLFRWQTDTNILIAIQLFVSQKGMEHQAANTGLQTMIEILIQAQQAAVIAAISASTAATSASSNS
>NC_009674.1|WP_012094502.1|2141898_2142366_-|NUDIX-hydrolase
MDLTFQVNQSCFNYRVGAICKHDNKILMLQNEGEDFWYVPGGRVQLLETSEVAIKRELKEELGVDVAVKRPLWIVENFFTYDSRQFHEISLYYEVNLLTLPVKGADSFLFEEEGRKYKFQWIPLEQICEYNVKPEFLKDKMTQLPLHVEHIVKNQ
>NC_009674.1|WP_012094504.1|2143099_2144140_-|SDR-family-oxidoreductase
MKVLILGGTRFLGRALVEEALKRGHEVTLFNRGTNKEIFPKVEQLIGDRDGDVSALKNRNWDIVMDTCGFAPHQIRNIATILGGNIEHYTFISSMSTYKDWIPLHIKEDYQLQSIPPREKLKAIEDGEASPYEYYGGLKVLCEKEAEKYWPGRVLHMRAGLLVGAFDYTDRLPYWIQRVAQGGEVLVPEHSNRPVQLIDVKDVATWAFNMAEGRKVGTFNVTGPNNELTIGELLNTCKAVTNSDAEFVWVEEQFLLENKVQPWTEMPLWIPETFPLEGETEPWKGSFFISIEKAVNAGLSFRPIQNTISDVYQWEKSRKDTERKAGMAREKERELLKLWFQQEKMR

You can click texts colored in the table to view more detailed information

Click the colored protein region to show detailed information

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NC_009674_3	3.2\|2135762\|37\|NC_009674\|CRISPRCasFinder,CRT	2135762-2135798	37	NZ_CP007513	Bacillus bombysepticus plasmid pBb, complete genome	248075-248111	5	0.865
NC_009674_3	3.9\|2135763\|37\|NC_009674\|PILER-CR	2135763-2135799	37	NZ_CP007513	Bacillus bombysepticus plasmid pBb, complete genome	248075-248111	5	0.865
NC_009674_3	3.6\|2136024\|37\|NC_009674\|CRISPRCasFinder,CRT	2136024-2136060	37	NC_025146	Clostridium botulinum plasmid pCB111 DNA, complete sequence, strain: 111	92131-92167	8	0.784
NC_009674_3	3.13\|2136025\|37\|NC_009674\|PILER-CR	2136025-2136061	37	NC_025146	Clostridium botulinum plasmid pCB111 DNA, complete sequence, strain: 111	92131-92167	8	0.784
NC_009674_3	3.4\|2135893\|36\|NC_009674\|CRISPRCasFinder,CRT	2135893-2135928	36	NZ_CP026684	Nostoc sp. 'Peltigera membranacea cyanobiont' N6 plasmid pNPM2, complete sequence	126541-126576	11	0.694
NC_009674_3	3.11\|2135894\|36\|NC_009674\|PILER-CR	2135894-2135929	36	NZ_CP026684	Nostoc sp. 'Peltigera membranacea cyanobiont' N6 plasmid pNPM2, complete sequence	126541-126576	11	0.694

1. spacer 3.2|2135762|37|NC_009674|CRISPRCasFinder,CRT matches to NZ_CP007513 (Bacillus bombysepticus plasmid pBb, complete genome) position: , mismatch: 5, identity: 0.865

tgggacaaacatgctactttcttgaacgctcagtcaa-	CRISPR spacer
tgggacaaacatgctacttttttaaa-gcccaatcaag	Protospacer
********************.**.** **.**.****

2. spacer 3.9|2135763|37|NC_009674|PILER-CR matches to NZ_CP007513 (Bacillus bombysepticus plasmid pBb, complete genome) position: , mismatch: 5, identity: 0.865

tgggacaaacatgctactttcttgaacgctcagtcaa-	CRISPR spacer
tgggacaaacatgctacttttttaaa-gcccaatcaag	Protospacer
********************.**.** **.**.****

3. spacer 3.6|2136024|37|NC_009674|CRISPRCasFinder,CRT matches to NC_025146 (Clostridium botulinum plasmid pCB111 DNA, complete sequence, strain: 111) position: , mismatch: 8, identity: 0.784

tgaacc---atttttcaataatcaatattcctttcttaag	CRISPR spacer
---actttaatttttcaaaaattaatattcctttcttatt	Protospacer
   **.   ********* ***.***************

4. spacer 3.13|2136025|37|NC_009674|PILER-CR matches to NC_025146 (Clostridium botulinum plasmid pCB111 DNA, complete sequence, strain: 111) position: , mismatch: 8, identity: 0.784

tgaacc---atttttcaataatcaatattcctttcttaag	CRISPR spacer
---actttaatttttcaaaaattaatattcctttcttatt	Protospacer
   **.   ********* ***.***************

5. spacer 3.4|2135893|36|NC_009674|CRISPRCasFinder,CRT matches to NZ_CP026684 (Nostoc sp. 'Peltigera membranacea cyanobiont' N6 plasmid pNPM2, complete sequence) position: , mismatch: 11, identity: 0.694

ccgtgttggtggcgttggtggtgcattgcaaaccgt	CRISPR spacer
agactttggtggtgttggaggtgcattgcaaaaaca	Protospacer
  .. *******.***** *************

6. spacer 3.11|2135894|36|NC_009674|PILER-CR matches to NZ_CP026684 (Nostoc sp. 'Peltigera membranacea cyanobiont' N6 plasmid pNPM2, complete sequence) position: , mismatch: 11, identity: 0.694

ccgtgttggtggcgttggtggtgcattgcaaaccgt	CRISPR spacer
agactttggtggtgttggaggtgcattgcaaaaaca	Protospacer
  .. *******.***** *************

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

268954 : 276933

uncultured_virus(33.33%)

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_011983376.1\|268954_269239_+	co-chaperone GroES	A0A221S3C8	uncultured_virus	5.8e-20	52.7
WP_011983377.1\|269273_270902_+	chaperonin GroEL	A0A219YK78	uncultured_virus	1.5e-157	56.9
WP_164468623.1\|271334_272876_+	glutamine-hydrolyzing GMP synthase	A0A1V0SH76	Hokovirus	1.7e-20	30.6
WP_011983379.1\|273249_274575_+	NCS2 family permease	A0A0R6PHV4	Moraxella_phage	2.9e-45	31.6
WP_041810187.1\|274718_275420_+	response regulator transcription factor	W8CYM9	Bacillus_phage	8.6e-41	38.7
WP_041810188.1\|275415_276933_+	HAMP domain-containing histidine kinase	W8CYF6	Bacillus_phage	2.9e-33	30.4

DBSCAN-SWA_2

309936 : 318308

Synechococcus_phage(33.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_011983391.1\|309936_311238_+	adenylosuccinate lyase	A0A1B3B081	Gordonia_phage	2.0e-19	31.6
WP_011983392.1\|311332_312052_+	phosphoribosylaminoimidazolesuccinocarboxamide synthase	G8EYA2	Synechococcus_phage	9.8e-48	43.9
WP_011983393.1\|312044_312299_+	phosphoribosylformylglycinamidine synthase subunit PurS	NA	NA	NA	NA
WP_011983394.1\|312295_312979_+	phosphoribosylformylglycinamidine synthase subunit PurQ	NA	NA	NA	NA
WP_011983395.1\|312962_315182_+	phosphoribosylformylglycinamidine synthase II	A6N228	Microbacterium_phage	1.5e-160	41.3
WP_011983396.1\|315166_316582_+	amidophosphoribosyltransferase	A0A0M3SGR2	Mollivirus	9.5e-55	35.4
WP_011983397.1\|316684_317728_+	phosphoribosylformylglycinamidine cyclo-ligase	Q58MH8	Prochlorococcus_phage	2.7e-70	48.0
WP_011983398.1\|317720_318308_+	phosphoribosylglycinamide formyltransferase	M4QRX9	Synechococcus_phage	1.6e-24	34.2

DBSCAN-SWA_3

747803 : 764083

Orpheovirus(25.0%)

coat,transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_011983759.1\|747803_748373_-\|coat	spore coat protein CotJC	NA	NA	NA	NA
WP_011983760.1\|748385_748649_-\|coat	spore coat protein CotJB	NA	NA	NA	NA
WP_011983761.1\|748657_748873_-\|coat	spore coat associated protein CotJA	NA	NA	NA	NA
WP_011983762.1\|748999_749356_+	VOC family protein	NA	NA	NA	NA
WP_011983763.1\|749418_750198_+	DUF2935 domain-containing protein	A0A2I2L551	Orpheovirus	9.9e-38	34.0
WP_011983764.1\|750416_750698_+	DUF1232 domain-containing protein	NA	NA	NA	NA
WP_011983765.1\|750823_751204_+	DUF3992 domain-containing protein	NA	NA	NA	NA
WP_011983766.1\|751217_751571_+	DUF3992 domain-containing protein	NA	NA	NA	NA
WP_011983767.1\|751640_752093_-	hypothetical protein	NA	NA	NA	NA
WP_041809466.1\|752674_752875_+	hypothetical protein	NA	NA	NA	NA
WP_011983770.1\|753311_754439_+	cation:proton antiporter	NA	NA	NA	NA
WP_011983771.1\|754637_755501_+	MurR/RpiR family transcriptional regulator	NA	NA	NA	NA
WP_011983772.1\|755666_755984_+	DUF4870 domain-containing protein	A0A2H4JDX0	uncultured_Caudovirales_phage	3.3e-08	37.6
WP_011983773.1\|756150_757035_+	N-acetylmuramic acid 6-phosphate etherase	NA	NA	NA	NA
WP_011983774.1\|757058_758426_+	PTS transporter subunit EIIC	NA	NA	NA	NA
WP_011983775.1\|758703_759300_+\|transposase	transposase	A0A146ICT8	Staphylococcus_phage	4.6e-35	42.9
WP_081428346.1\|759278_759509_+\|transposase	transposase	NA	NA	NA	NA
WP_109456140.1\|760080_762372_-	DUF3238 domain-containing protein	A0A2I7SDE4	Paenibacillus_phage	3.1e-07	35.2
WP_011983777.1\|762811_764083_-\|transposase	IS4-like element ISBce12 family transposase	NA	NA	NA	NA

DBSCAN-SWA_4

2644415 : 2714698

Bacillus_phage(77.78%)

protease,terminase,capsid,head,tRNA,portal,tail

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_012094985.1\|2644415_2647181_-\|tRNA	isoleucine--tRNA ligase	A0A2K9L9X8	Tupanvirus	2.8e-87	27.3
WP_012094986.1\|2647525_2648032_-	septum site-determining protein DivIVA	NA	NA	NA	NA
WP_012094987.1\|2648124_2648898_-	RNA-binding protein	NA	NA	NA	NA
WP_012094988.1\|2648912_2649176_-	YggT family protein	NA	NA	NA	NA
WP_012094989.1\|2649182_2649653_-	cell division protein SepF	NA	NA	NA	NA
WP_012094990.1\|2649671_2650346_-	YggS family pyridoxal phosphate-dependent enzyme	NA	NA	NA	NA
WP_012094991.1\|2650352_2651162_-	peptidoglycan editing factor PgeF	NA	NA	NA	NA
WP_012094992.1\|2651279_2651558_-	YlmC/YmxH family sporulation protein	NA	NA	NA	NA
WP_012094993.1\|2651821_2652601_-	RNA polymerase sporulation sigma factor SigG	A0A0Y0AU18	Bacillus_phage	3.4e-46	43.4
WP_012094994.1\|2652792_2653512_-	RNA polymerase sporulation sigma factor SigE	A0A2H4JC68	uncultured_Caudovirales_phage	2.5e-19	42.9
WP_012094995.1\|2653531_2654449_-	sigma-E processing peptidase SpoIIGA	NA	NA	NA	NA
WP_012094996.1\|2654673_2655828_-	cell division protein FtsZ	NA	NA	NA	NA
WP_012094997.1\|2655867_2657172_-	cell division protein FtsA	NA	NA	NA	NA
WP_012094999.1\|2657572_2658340_-	cell division protein DivIB	NA	NA	NA	NA
WP_041810494.1\|2658437_2659343_-	UDP-N-acetylmuramate dehydrogenase	NA	NA	NA	NA
WP_012095001.1\|2659403_2660498_-	undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase	NA	NA	NA	NA
WP_012095002.1\|2660682_2661774_-	stage V sporulation protein E	NA	NA	NA	NA
WP_012095003.1\|2661865_2663221_-	UDP-N-acetylmuramoyl-L-alanine--D-glutamate ligase	NA	NA	NA	NA
WP_012095004.1\|2663221_2664196_-	phospho-N-acetylmuramoyl-pentapeptide- transferase	NA	NA	NA	NA
WP_012095005.1\|2664218_2665694_-	UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2, 6-diaminopimelate ligase	NA	NA	NA	NA
WP_012095006.1\|2665966_2667883_-	stage V sporulation protein D	NA	NA	NA	NA
WP_041810497.1\|2667980_2670131_-	penicillin-binding protein	NA	NA	NA	NA
WP_012095008.1\|2670153_2670510_-	cell division protein FtsL	NA	NA	NA	NA
WP_012095009.1\|2670525_2671458_-	16S rRNA (cytosine(1402)-N(4))-methyltransferase RsmH	NA	NA	NA	NA
WP_012095010.1\|2671821_2673438_-	bacillithiol biosynthesis cysteine-adding enzyme BshC	NA	NA	NA	NA
WP_041810499.1\|2673517_2674402_-	2-dehydropantoate 2-reductase	NA	NA	NA	NA
WP_012095012.1\|2674703_2675177_+	N-acetyltransferase	NA	NA	NA	NA
WP_012095013.1\|2675272_2675794_-	RsfA family transcriptional regulator	G3MB11	Bacillus_virus	4.0e-11	47.8
WP_001984764.1\|2676053_2676227_-	50S ribosomal protein L32	NA	NA	NA	NA
WP_012095016.1\|2676288_2676789_-	DUF177 domain-containing protein	NA	NA	NA	NA
WP_041809924.1\|2677070_2677691_-	replication-relaxation family protein	Q2LIA9	Bacillus_phage	1.0e-85	76.8
WP_012095018.1\|2677632_2678814_-	cell division protein FtsK	Q3HKZ7	Bacillus_phage	3.0e-195	84.5
WP_012095019.1\|2678931_2679114_-	hypothetical protein	Q2I8E2	Bacillus_phage	3.9e-22	88.3
WP_012095020.1\|2679116_2679419_-	hypothetical protein	A0A288WG38	Bacillus_phage	1.7e-46	89.9
WP_012095022.1\|2679578_2679776_+	helix-turn-helix domain-containing protein	A0A288WG74	Bacillus_phage	2.7e-24	89.2
WP_041809926.1\|2679781_2680108_+	hypothetical protein	A0A0S2GLG3	Bacillus_phage	7.0e-46	86.1
WP_012095024.1\|2680143_2681208_-	N-acetylmuramoyl-L-alanine amidase	A0A0A7AQV3	Bacillus_phage	2.3e-178	85.9
WP_012095025.1\|2681204_2681444_-	hypothetical protein	A0A2H4J378	uncultured_Caudovirales_phage	1.2e-29	87.3
WP_041809928.1\|2681443_2681680_-	hemolysin XhlA family protein	A0A2H4J382	uncultured_Caudovirales_phage	1.2e-07	78.2
WP_012095028.1\|2685746_2687240_-\|tail	phage tail family protein	A0A2H4JC38	uncultured_Caudovirales_phage	1.1e-255	84.3
WP_012095029.1\|2687248_2691289_-\|tail	phage tail tape measure protein	H0USX3	Bacillus_phage	0.0e+00	75.3
WP_012095031.1\|2691505_2691820_-	hypothetical protein	A0A288WFU6	Bacillus_phage	1.8e-35	70.2
WP_012095032.1\|2691868_2692480_-\|tail	tail protein	A0A2H4J8F3	uncultured_Caudovirales_phage	8.4e-101	94.5
WP_012095033.1\|2692480_2692840_-	DUF3168 domain-containing protein	A0A0S2GLE3	Bacillus_phage	1.4e-55	90.8
WP_012095034.1\|2692836_2693271_-	HK97 gp10 family phage protein	A0A288WGB7	Bacillus_phage	3.7e-66	85.6
WP_012095035.1\|2693263_2693587_-\|head	phage head closure protein	A0A288WG18	Bacillus_phage	8.0e-50	85.0
WP_012095036.1\|2693583_2693874_-\|head,tail	phage gp6-like head-tail connector protein	A0A288WGQ6	Bacillus_phage	3.6e-41	88.5
WP_012095037.1\|2693891_2695067_-\|capsid	phage major capsid protein	A0A288WG01	Bacillus_phage	2.4e-184	87.5
WP_041809932.1\|2695108_2695729_-\|head,protease	HK97 family phage prohead protease	Q2I8F8	Bacillus_phage	2.9e-101	89.8
WP_012095039.1\|2695670_2696981_-\|portal	phage portal protein	Q2LIC9	Bacillus_phage	6.4e-215	89.2
WP_012095040.1\|2696996_2698694_-\|terminase	terminase large subunit	A0A288WFW5	Bacillus_phage	0.0e+00	92.0
WP_012095041.1\|2698690_2699176_-\|terminase	phage terminase small subunit P27 family	A0A288WG26	Bacillus_phage	9.4e-79	96.3
WP_012095042.1\|2699275_2699659_-	HNH endonuclease	Q2I8B2	Bacillus_phage	2.2e-62	90.6
WP_049759299.1\|2699865_2700177_-	hypothetical protein	A0A288WG64	Bacillus_phage	5.0e-25	69.1
WP_012095044.1\|2700486_2700741_-	hypothetical protein	A0A288WG25	Bacillus_phage	2.5e-30	73.8
WP_012095045.1\|2700760_2700952_-	hypothetical protein	A0A288WFV5	Bacillus_phage	1.7e-23	88.9
WP_012095046.1\|2700957_2701176_-	hypothetical protein	D2XR60	Bacillus_phage	3.3e-23	73.6
WP_012095047.1\|2701470_2701848_-	ArpU family transcriptional regulator	Q9ZXB9	Bacillus_phage	1.0e-16	39.7
WP_109090152.1\|2701905_2702247_-	hypothetical protein	NA	NA	NA	NA
WP_041810509.1\|2702266_2702494_-	hypothetical protein	A0A288WFX6	Bacillus_phage	2.2e-22	68.0
WP_012095049.1\|2702539_2703085_-	hypothetical protein	A0A1I9S5V4	Bacillus_phage	3.5e-66	78.0
WP_012095050.1\|2703145_2703409_-	hypothetical protein	NA	NA	NA	NA
WP_012095051.1\|2703447_2704176_-	sigma-70 family RNA polymerase sigma factor	A0A288WFV7	Bacillus_phage	6.4e-55	46.9
WP_012095052.1\|2704168_2704567_-	hypothetical protein	NA	NA	NA	NA
WP_109090167.1\|2704575_2705442_-	zinc-finger domain-containing protein	NA	NA	NA	NA
WP_012095055.1\|2705536_2706247_-	hypothetical protein	NA	NA	NA	NA
WP_012095059.1\|2706262_2706679_-	DUF1064 domain-containing protein	A0A2P1JTY5	Anoxybacillus_phage	1.2e-34	56.3
WP_012095060.1\|2706671_2707166_-	deoxyuridine 5'-triphosphate nucleotidohydrolase	A0A1B1P8C0	Bacillus_phage	3.2e-58	70.6
WP_109090168.1\|2707382_2707703_-	hypothetical protein	A0A0A7AQW3	Bacillus_phage	1.8e-25	49.0
WP_012095062.1\|2707849_2708332_-	YpiB family protein	NA	NA	NA	NA
WP_041809938.1\|2708312_2708507_-	hypothetical protein	NA	NA	NA	NA
WP_049759300.1\|2708512_2709145_-	ATP-binding protein	A0A0S2GLK2	Bacillus_phage	4.1e-58	50.7
WP_012095064.1\|2709275_2710241_-	DnaD domain protein	H0USU2	Bacillus_phage	9.7e-43	51.9
WP_012095065.1\|2710415_2711222_-	recombination protein RecT	S6AVW6	Thermus_phage	3.4e-97	66.9
WP_041809942.1\|2711221_2711461_-	hypothetical protein	NA	NA	NA	NA
WP_012095067.1\|2711475_2712411_-	YqaJ viral recombinase family protein	S6C475	Thermus_phage	1.9e-99	59.5
WP_012095068.1\|2712492_2712708_-	hypothetical protein	NA	NA	NA	NA
WP_041810513.1\|2712883_2713177_-	hypothetical protein	A0A0S2GLB6	Bacillus_phage	1.0e-27	62.4
WP_012095070.1\|2713184_2713505_-	hypothetical protein	NA	NA	NA	NA
WP_167527342.1\|2713501_2713672_-	hypothetical protein	NA	NA	NA	NA
WP_012095071.1\|2713652_2713862_-	helix-turn-helix domain-containing protein	A0A0U4IIS1	Bacillus_phage	4.4e-09	50.9
WP_049759301.1\|2713984_2714194_-	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_012095072.1\|2714359_2714698_+	helix-turn-helix transcriptional regulator	H0UST7	Bacillus_phage	1.3e-21	53.3

DBSCAN-SWA_5

2990393 : 3021377

Bacillus_phage(91.67%)

terminase,capsid,head,holin,portal,tail

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_012095391.1\|2990393_2990834_-\|holin	phage holin family protein	A0A1B1P7S2	Bacillus_phage	8.3e-66	86.3
WP_012095393.1\|2995358_2996852_-\|tail	phage tail family protein	A0A1B1P7W7	Bacillus_phage	1.6e-230	76.1
WP_012095394.1\|2996864_2999792_-\|tail	phage tail tape measure protein	A0A0A7AR36	Bacillus_phage	2.9e-183	55.7
WP_012095395.1\|2999797_3000064_-	hypothetical protein	A0A0M4S6X7	Bacillus_phage	8.3e-21	60.2
WP_012095396.1\|3000099_3000537_-	hypothetical protein	A0A0M4QX42	Bacillus_phage	3.6e-13	32.7
WP_012095397.1\|3000582_3001215_-	hypothetical protein	A0A0M4R5F9	Bacillus_phage	2.6e-76	79.7
WP_012095398.1\|3001232_3001613_-	hypothetical protein	A0A0M4RD75	Bacillus_phage	3.9e-56	82.5
WP_012095399.1\|3001609_3002026_-	hypothetical protein	A0A0M4S6Z2	Bacillus_phage	2.7e-58	76.8
WP_012095400.1\|3002009_3002369_-	hypothetical protein	A0A0M4S6Z9	Bacillus_phage	5.7e-49	81.2
WP_012095401.1\|3002350_3002689_-\|head,tail	phage head-tail connector protein	W8CYS9	Bacillus_phage	2.9e-10	39.6
WP_012095402.1\|3002725_3003568_-	hypothetical protein	A0A0M5M1L4	Bacillus_phage	5.2e-117	77.7
WP_012095403.1\|3003581_3004172_-	DUF4355 domain-containing protein	A0A0M3ULE7	Bacillus_phage	4.6e-19	55.8
WP_012095404.1\|3004241_3005267_-\|capsid	minor capsid protein	A0A0M5M7Z2	Bacillus_phage	5.1e-159	84.1
WP_012095405.1\|3005253_3006609_-\|portal	phage portal protein	A0A0M4S669	Bacillus_phage	3.5e-200	85.6
WP_012095406.1\|3006620_3007925_-\|terminase	PBSX family phage terminase large subunit	A0A0M4R5F3	Bacillus_phage	9.5e-251	95.2
WP_012095407.1\|3007911_3008343_-\|terminase	terminase small subunit	A0A0M4RU19	Bacillus_phage	9.3e-54	72.8
WP_012095408.1\|3009080_3009503_-	ArpU family phage transcriptional regulator	A0A0M4R397	Bacillus_phage	2.4e-22	49.2
WP_012095409.1\|3009496_3009886_-	DUF1064 domain-containing protein	A0A1B1P859	Bacillus_phage	5.6e-50	75.0
WP_167527344.1\|3009914_3010205_-	hypothetical protein	NA	NA	NA	NA
WP_041810013.1\|3010345_3010579_-	hypothetical protein	NA	NA	NA	NA
WP_167527345.1\|3010664_3010811_-	hypothetical protein	NA	NA	NA	NA
WP_012095411.1\|3010829_3011114_-	hypothetical protein	I7J4K9	Bacillus_phage	4.3e-15	48.9
WP_012095412.1\|3011283_3011481_-	hypothetical protein	H0USU7	Bacillus_phage	3.6e-29	92.1
WP_041810559.1\|3011586_3012216_-	hypothetical protein	A0A0M4RU33	Bacillus_phage	6.1e-30	43.5
WP_012095414.1\|3012385_3012787_-	hypothetical protein	A0A1B1P7W5	Bacillus_phage	7.6e-26	51.0
WP_041810016.1\|3012773_3012968_-	hypothetical protein	NA	NA	NA	NA
WP_012095416.1\|3012939_3013167_-	hypothetical protein	NA	NA	NA	NA
WP_049759262.1\|3013177_3014050_-	ATP-binding protein	A0A0M4RD64	Bacillus_phage	1.4e-112	70.6
WP_041810018.1\|3013979_3014783_-	conserved phage C-terminal domain-containing protein	A0A0M4S6Y4	Bacillus_phage	5.9e-86	75.4
WP_012095418.1\|3014783_3015053_-	hypothetical protein	A0A0M4S680	Bacillus_phage	5.3e-39	83.1
WP_012095419.1\|3015066_3015738_-	DUF1071 domain-containing protein	A0A1B1P7F0	Bacillus_phage	8.0e-28	44.2
WP_012095420.1\|3015734_3016217_-	siphovirus Gp157 family protein	E5DV79	Deep-sea_thermophilic_phage	8.3e-35	48.1
WP_012095421.1\|3016280_3016649_-	helix-turn-helix transcriptional regulator	A0A0M5M3T1	Bacillus_phage	2.9e-11	81.0
WP_012095422.1\|3016671_3016938_-	hypothetical protein	A0A0M4S677	Bacillus_phage	2.3e-23	80.9
WP_157671227.1\|3017085_3017229_-	hypothetical protein	A0A0M4REP5	Bacillus_phage	3.7e-15	80.4
WP_012095423.1\|3017257_3017446_-	hypothetical protein	NA	NA	NA	NA
WP_012095424.1\|3017480_3017756_-	hypothetical protein	S5MC08	Brevibacillus_phage	3.6e-27	59.3
WP_012095425.1\|3017782_3018619_-	ORF6C domain-containing protein	A0A0M5M1L9	Bacillus_phage	4.8e-123	82.7
WP_012095426.1\|3018615_3018804_-	helix-turn-helix transcriptional regulator	A0A0M3ULF9	Bacillus_phage	1.1e-22	91.4
WP_012095427.1\|3019076_3019499_+	helix-turn-helix transcriptional regulator	A0A0M4QX29	Bacillus_phage	5.9e-69	96.4
WP_012095428.1\|3019513_3019939_+	ImmA/IrrE family metallo-endopeptidase	A0A0M4RD70	Bacillus_phage	7.5e-72	92.2
WP_012095429.1\|3019952_3021377_+	recombinase family protein	A0A1L2JY12	Aeribacillus_phage	7.2e-103	42.4

DBSCAN-SWA_6

3182623 : 3241413

Klosneuvirus(25.0%)

tRNA,coat,protease

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_012095594.1\|3182623_3183763_-\|tRNA	tRNA guanosine(34) transglycosylase Tgt	A0A1B1IVQ4	uncultured_Mediterranean_phage	4.3e-82	41.5
WP_012095595.1\|3183778_3184831_-\|tRNA	tRNA preQ1(34) S-adenosylmethionine ribosyltransferase-isomerase QueA	NA	NA	NA	NA
WP_012095596.1\|3184849_3185050_-	DUF2905 domain-containing protein	NA	NA	NA	NA
WP_012095597.1\|3185046_3186048_-	Holliday junction branch migration DNA helicase RuvB	A0A127AWE7	Bacillus_phage	2.3e-07	27.5
WP_012095598.1\|3186053_3186671_-	Holliday junction DNA helicase RuvA	NA	NA	NA	NA
WP_041810044.1\|3186858_3187800_+	iron-hydroxamate ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_012095600.1\|3187827_3188337_-	BofC C-terminal domain-containing protein	NA	NA	NA	NA
WP_012095601.1\|3188847_3189525_-	YhcN/YlaJ family sporulation lipoprotein	NA	NA	NA	NA
WP_012095602.1\|3189640_3191665_-\|coat	SafA/ExsA family spore coat assembly protein	NA	NA	NA	NA
WP_012095603.1\|3191914_3193021_-	quinolinate synthase NadA	NA	NA	NA	NA
WP_012095604.1\|3193051_3193885_-	carboxylating nicotinate-nucleotide diphosphorylase	NA	NA	NA	NA
WP_012095605.1\|3193915_3195424_-	L-aspartate oxidase	NA	NA	NA	NA
WP_012095606.1\|3195588_3196731_+	IscS subfamily cysteine desulfurase	NA	NA	NA	NA
WP_012095607.1\|3196730_3197276_+	transcription repressor NadR	NA	NA	NA	NA
WP_012095608.1\|3197363_3198011_+	MOSC domain-containing protein	NA	NA	NA	NA
WP_012095609.1\|3198202_3199054_-	prephenate dehydratase	NA	NA	NA	NA
WP_012095610.1\|3199150_3201064_-	ABC transporter permease	NA	NA	NA	NA
WP_012095611.1\|3201113_3203036_-	ABC transporter permease	NA	NA	NA	NA
WP_012095612.1\|3203010_3203787_-	ABC transporter ATP-binding protein	W5SAS9	Pithovirus	4.6e-19	30.6
WP_012095613.1\|3203880_3204963_-	HAMP domain-containing histidine kinase	NA	NA	NA	NA
WP_012095614.1\|3204952_3205660_-	response regulator transcription factor	NA	NA	NA	NA
WP_012095615.1\|3205798_3207085_-	GTPase ObgE	NA	NA	NA	NA
WP_012095616.1\|3207089_3207632_-	Spo0B domain-containing protein	NA	NA	NA	NA
WP_012095617.1\|3207696_3207987_-	50S ribosomal protein L27	NA	NA	NA	NA
WP_012095618.1\|3207990_3208335_-\|protease	ribosomal-processing cysteine protease Prp	NA	NA	NA	NA
WP_000270908.1\|3208346_3208655_-	50S ribosomal protein L21	NA	NA	NA	NA
WP_012095619.1\|3208820_3210212_-	Rne/Rng family ribonuclease	NA	NA	NA	NA
WP_012095620.1\|3210276_3211137_-\|protease	site-2 protease family protein	NA	NA	NA	NA
WP_012095621.1\|3211129_3211873_-	M23 family metallopeptidase	NA	NA	NA	NA
WP_012095622.1\|3212030_3212828_-	septum site-determining protein MinD	NA	NA	NA	NA
WP_012095623.1\|3212830_3213517_-	septum site-determining protein MinC	NA	NA	NA	NA
WP_012095624.1\|3213552_3214095_-	rod shape-determining protein MreD	NA	NA	NA	NA
WP_012095625.1\|3214107_3214965_-	rod shape-determining protein MreC	NA	NA	NA	NA
WP_012095626.1\|3215006_3216023_-	rod shape-determining protein MreB	NA	NA	NA	NA
WP_012095629.1\|3218823_3219381_-	DNA repair protein RadC	NA	NA	NA	NA
WP_012095630.1\|3219428_3220004_-	septum formation inhibitor Maf	NA	NA	NA	NA
WP_012095631.1\|3220384_3221347_-	stage II sporulation protein B	NA	NA	NA	NA
WP_012095632.1\|3221516_3222818_-	bifunctional folylpolyglutamate synthase/dihydrofolate synthase	NA	NA	NA	NA
WP_012095633.1\|3222932_3225578_-\|tRNA	valine--tRNA ligase	A0A1V0SK04	Klosneuvirus	1.2e-162	42.4
WP_041810566.1\|3226121_3226316_+	hypothetical protein	NA	NA	NA	NA
WP_012095634.1\|3226330_3227359_-\|coat	spore coat protein YsxE	NA	NA	NA	NA
WP_041810050.1\|3227426_3228461_-	stage VI sporulation protein D	NA	NA	NA	NA
WP_012095636.1\|3228574_3229864_-	glutamate-1-semialdehyde 2,1-aminomutase	A0A1V0SKB7	Klosneuvirus	1.3e-05	35.2
WP_012095637.1\|3229863_3230853_-	porphobilinogen synthase	NA	NA	NA	NA
WP_012095638.1\|3230882_3231641_-	uroporphyrinogen-III synthase	NA	NA	NA	NA
WP_012095639.1\|3231643_3232573_-	hydroxymethylbilane synthase	NA	NA	NA	NA
WP_012095640.1\|3232588_3233422_-	cytochrome c biogenesis protein CcsA	NA	NA	NA	NA
WP_012095641.1\|3233439_3234774_-\|tRNA	glutamyl-tRNA reductase	NA	NA	NA	NA
WP_012095642.1\|3235174_3235771_-	YihA family ribosome biogenesis GTP-binding protein	NA	NA	NA	NA
WP_041810052.1\|3235767_3238098_-	endopeptidase La	A0A0R6PGP8	Moraxella_phage	7.8e-179	44.0
WP_012095644.1\|3238372_3240043_-\|protease	ATP-dependent protease LonB	E3T4F6	Cafeteria_roenbergensis_virus	1.5e-14	33.1
WP_012095645.1\|3240153_3241413_-\|protease	ATP-dependent Clp protease ATP-binding subunit ClpX	G3M9Z9	Bacillus_virus	1.2e-149	66.6

DBSCAN-SWA_7

4045694 : 4052347

uncultured_Caudovirales_phage(66.67%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_012096430.1\|4045694_4046111_-	immunity 70 family protein	A0A2H4J4V0	uncultured_Caudovirales_phage	5.0e-28	46.3
WP_012096431.1\|4046127_4047315_-	WXG100 family type VII secretion target	A0A2H4J389	uncultured_Caudovirales_phage	1.1e-152	69.0
WP_012096432.1\|4047540_4048635_+	tetratricopeptide repeat protein	A0A2H4J8G3	uncultured_Caudovirales_phage	2.3e-125	63.1
WP_012096433.1\|4048631_4048856_+	Phr family secreted Rap phosphatase inhibitor	A0A2H4JBB8	uncultured_Caudovirales_phage	4.4e-07	48.6
WP_012096434.1\|4049074_4050355_-	hypothetical protein	NA	NA	NA	NA
WP_012096435.1\|4050338_4051181_-	DNA adenine methylase	A0A1S5PRR3	Streptococcus_phage	1.1e-79	52.9
WP_012096436.1\|4051759_4052347_-	recombinase family protein	A0JC18	Ralstonia_phage	1.2e-19	39.3

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. NC_009674

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection