CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NC_010740	Brucella abortus S19 chromosome 2, complete sequence	1 crisprs	csa3,cas3,DEDDh	0	0	0	0
NC_010742	Brucella abortus S19 chromosome 1, complete sequence	0 crisprs	csa3,WYL,DEDDh	0	0	2	0

Results visualization

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CRISPR-Cas detection and classification

Crispr_ID: NC_010740_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_010740_1

182037-182137

Orphan

Consensus_repeat	Method
ATGGACTTCTTGGAAGTCCATGCCGCCC	CRISPRCasFinder

1 spacers

The CRISPR arrays of NC_010740_1

>merge|NC_010740|1|182037-182137|CRISPRCasFinder
ATGGACTTCTTGGAAGTCCATGCCGCCCCCGCGCCGCTTTGCGGCGCAGGCATTTAGTTCATGGGCGAGCTTTATGGACTTCTTAGAAGTCCATGCCGCCC

>NC_010740|1|1|182037-182137|CRISPRCasFinder
ATGGACTTCTTGGAAGTCCATGCCGCCC	CCGCGCCGCTTTGCGGCGCAGGCATTTAGTTCATGGGCGAGCTTT
ATGGACTTCTTAGAAGTCCATGCCGCCC

Protein	Signature genes	Signature genes Name	Protein_function
NC_010740.1\|WP_002966377.1\|193975_194539_+\|16S-rRNA-(guanine(966)-N(2))-methyltransferase-RsmD	unknown	unknown	gnl\|CDD\|223813
NC_010740.1\|WP_002972151.1\|181111_181366_-\|hypothetical-protein	unknown	unknown	unknown
NC_010740.1\|WP_002967192.1\|191021_191582_+\|cytochrome-b	unknown	unknown	gnl\|CDD\|225580
NC_010740.1\|WP_002966393.1\|176774_177470_+\|ATP-phosphoribosyltransferase	unknown	unknown	gnl\|CDD\|237438
NC_010740.1\|WP_002966392.1\|177542_178781_-\|sugar-MFS-transporter	unknown	unknown	gnl\|CDD\|340952
NC_010740.1\|WP_002966391.1\|179066_179468_-\|DoxX-family-protein	unknown	unknown	gnl\|CDD\|225168
NC_010740.1\|WP_002971287.1\|190005_190677_+\|hypothetical-protein	unknown	unknown	unknown
NC_010740.1\|WP_002972147.1\|184626_185475_+\|TIGR01459-family-HAD-type-hydrolase	unknown	unknown	gnl\|CDD\|319827
NC_010740.1\|WP_002966382.1\|186895_189814_+\|isoleucine--tRNA-ligase	unknown	unknown	gnl\|CDD\|237514
NC_010740.1\|WP_002966396.1\|173402_174020_+\|LysE-family-translocator	unknown	unknown	gnl\|CDD\|224199
NC_010740.1\|WP_002966383.1\|185562_186552_+\|bifunctional-riboflavin-kinase/FAD-synthetase	unknown	unknown	gnl\|CDD\|235536
NC_010740.1\|WP_002966386.1\|183849_184146_-\|co-chaperone-GroES	unknown	unknown	gnl\|CDD\|178988
NC_010740.1\|WP_002966378.1\|192249_193995_+\|pseudouridine-synthase	unknown	unknown	gnl\|CDD\|224108
NC_010740.1\|WP_002966379.1\|191635_192109_-\|nucleoside-deaminase	unknown	unknown	gnl\|CDD\|223663
NC_010740.1\|WP_002969286.1\|194624_196169_+\|insulinase-family-protein	unknown	unknown	gnl\|CDD\|223685
NC_010740.1\|WP_002967189.1\|172627_173284_+\|DNA-3-methyladenine-glycosylase-I	unknown	unknown	gnl\|CDD\|377025
NC_010740.1\|WP_002968826.1\|174130_175639_+\|histidine--tRNA-ligase	unknown	unknown	gnl\|CDD\|223202
NC_010740.1\|WP_002972153.1\|175647_176778_+\|ATP-phosphoribosyltransferase-regulatory-subunit	unknown	unknown	gnl\|CDD\|183413
NC_010740.1\|WP_002966390.1\|179570_180962_-\|class-II-fumarate-hydratase	unknown	unknown	gnl\|CDD\|234779
NC_010740.1\|WP_002968994.1\|170551_171379_-\|aldo/keto-reductase	unknown	unknown	gnl\|CDD\|381357

Protein	Function_ID	Function_description	E-value
NC_010740.1\|WP_002966377.1\|193975_194539_+\|16S-rRNA-(guanine(966)-N(2))-methyltransferase-RsmD	gnl\|CDD\|223813	COG0742, COG0742, N6-adenine-specific methylase [DNA replication, recombination, and repair].	1.21532e-78
NC_010740.1\|WP_002966396.1\|173402_174020_+\|LysE-family-translocator	gnl\|CDD\|224199	COG1280, RhtB, Putative threonine efflux protein [Amino acid transport and metabolism].	9.51794e-45
NC_010740.1\|WP_002967192.1\|191021_191582_+\|cytochrome-b	gnl\|CDD\|225580	COG3038, CybB, Cytochrome B561 [Energy production and conversion].	7.89145e-52
NC_010740.1\|WP_002966393.1\|176774_177470_+\|ATP-phosphoribosyltransferase	gnl\|CDD\|237438	PRK13583, hisG, ATP phosphoribosyltransferase.	1.16784e-135
NC_010740.1\|WP_002966392.1\|177542_178781_-\|sugar-MFS-transporter	gnl\|CDD\|340952	cd17394, MFS_FucP_like, Fucose permease and similar proteins of the Major Facilitator Superfamily of transporters. This subfamily is composed of L-fucose permease (also called L-fucose-proton symporter) and similar proteins such as glucose/galactose transporter and N-acetyl glucosamine transporter NagP. L-fucose permease facilitates the uptake of L-fucose across the boundary membrane with the concomitant transport of protons into the cell; it can also transport L-galactose and D-arabinose. Glucose/galactose transporter functions in the uptake of of glucose and galactose. The FucP-like subfamily belongs to the bacterial fucose permease, eukaryotic Major facilitator superfamily domain-containing protein 4 (FucP/MFSD4) family of the Major Facilitator Superfamily (MFS) of transporters. MFS proteins are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	1.18971e-166
NC_010740.1\|WP_002966391.1\|179066_179468_-\|DoxX-family-protein	gnl\|CDD\|225168	COG2259, COG2259, Predicted membrane protein [Function unknown].	2.4232e-20
NC_010740.1\|WP_002966382.1\|186895_189814_+\|isoleucine--tRNA-ligase	gnl\|CDD\|237514	PRK13804, ileS, isoleucyl-tRNA synthetase; Provisional.	0
NC_010740.1\|WP_002972147.1\|184626_185475_+\|TIGR01459-family-HAD-type-hydrolase	gnl\|CDD\|319827	cd07525, HAD_like, uncharacterized family of the haloacid dehalogenase-like (HAD) hydrolase superfamily. The haloacid dehalogenase-like (HAD) hydrolases are a large superfamily of diverse enzymes that catalyze carbon or phosphoryl group transfer reactions on a range of substrates, using an active site aspartate in nucleophilic catalysis. Members include 2-L-haloalkanoic acid dehalogenase (C-Cl bond hydrolysis), azetidine hydrolase (C-N bond hydrolysis); phosphonoacetaldehyde hydrolase (C-P bond hydrolysis), phosphoserine phosphatase and phosphomannomutase (CO-P bond hydrolysis), P-type ATPases (PO-P bond hydrolysis) and many others. Members are found in all three kingdoms of life, and most genomes are predicted to contain multiple HAD-like proteins. Members possess a highly conserved alpha/beta core domain, and many also possess a small cap domain, the fold and function of which is variable. HAD hydrolases are sometimes referred to as belonging to the DDDD superfamily of phosphohydrolases.	2.51221e-90
NC_010740.1\|WP_002966383.1\|185562_186552_+\|bifunctional-riboflavin-kinase/FAD-synthetase	gnl\|CDD\|235536	PRK05627, PRK05627, bifunctional riboflavin kinase/FAD synthetase.	2.77791e-157
NC_010740.1\|WP_002966386.1\|183849_184146_-\|co-chaperone-GroES	gnl\|CDD\|178988	PRK00364, groES, co-chaperonin GroES; Reviewed.	5.80408e-54
NC_010740.1\|WP_002966378.1\|192249_193995_+\|pseudouridine-synthase	gnl\|CDD\|224108	COG1187, RsuA, 16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases [Translation, ribosomal structure and biogenesis].	6.08227e-83
NC_010740.1\|WP_002966379.1\|191635_192109_-\|nucleoside-deaminase	gnl\|CDD\|223663	COG0590, CumB, Cytosine/adenosine deaminases [Nucleotide transport and metabolism / Translation, ribosomal structure and biogenesis].	5.96751e-65
NC_010740.1\|WP_002969286.1\|194624_196169_+\|insulinase-family-protein	gnl\|CDD\|223685	COG0612, PqqL, Predicted Zn-dependent peptidases [General function prediction only].	4.11164e-117
NC_010740.1\|WP_002967189.1\|172627_173284_+\|DNA-3-methyladenine-glycosylase-I	gnl\|CDD\|377025	pfam03352, Adenine_glyco, Methyladenine glycosylase. The DNA-3-methyladenine glycosylase I is constitutively expressed and is specific for the alkylated 3-methyladenine DNA.	3.88001e-109
NC_010740.1\|WP_002968826.1\|174130_175639_+\|histidine--tRNA-ligase	gnl\|CDD\|223202	COG0124, HisS, Histidyl-tRNA synthetase [Translation, ribosomal structure and biogenesis].	2.87411e-159
NC_010740.1\|WP_002972153.1\|175647_176778_+\|ATP-phosphoribosyltransferase-regulatory-subunit	gnl\|CDD\|183413	PRK12295, hisZ, ATP phosphoribosyltransferase regulatory subunit; Provisional.	2.67267e-157
NC_010740.1\|WP_002966390.1\|179570_180962_-\|class-II-fumarate-hydratase	gnl\|CDD\|234779	PRK00485, fumC, fumarate hydratase; Reviewed.	0
NC_010740.1\|WP_002968994.1\|170551_171379_-\|aldo/keto-reductase	gnl\|CDD\|381357	cd19131, AKR_AKR5C2, Escherichia coli 2,5-diketo-D-gluconic acid reductase A (DkgA/YqhE) and similar proteins. Escherichia coli DkgA/YqhE is a founding member of aldo-keto reductase family 5 member C2 (AKR5C2). DkgA/YqhE (EC 1.1.1.274), also called 2,5-DKG reductase A, or 2,5-DKGR A, or 25DKGR-A, or AKR5C, catalyzes the reduction of 2,5-diketo-D-gluconic acid (25DKG) to 2-keto-L-gulonic acid (2KLG). It is also capable of stereoselective -keto ester reductions on ethyl acetoacetate and other 2-substituted derivatives.	3.08102e-178

>NC_010740.1|WP_002972151.1|181111_181366_-|hypothetical-protein
MRKELPIETAPKDGRKITVIWIDDDDQRNESIAQYRTLEQLRAGGGQWDEADTGWWTFTDNKTQRKIEPTAWIRETDDDESQED
>NC_010740.1|WP_002966390.1|179570_180962_-|class-II-fumarate-hydratase
MAATRTETDTFGPIDVPADRYWGAQTQRSLQNFRIGGERMPLPLVHALGVVKRAAAETNIALGKLDPVLGQVIAVAASEVIEGKLDDHFPLVVWQTGSGTQSNMNANEVISNRAIELLGGEMGSKKPIHPNDHVNMSQSSNDSFPTAIHIATAVETVNRLYPALEHLTKALKVKEEAFKDIIKIGRTHTQDATPVTLGQEFSGYRAALEYARHRLEQSLADVFLLAQGGTAVGTGLNAPVGFDKGFAEAVSEITGLSFKTAPNKFEALASHGAVLNFHGSLNALAADLFKIANDIRFLGSGPRSGLGELSLPENEPGSSIMPGKVNPTQAEAMTMVATQVFGNQTAVTVAASQGHFELNVFKPVIAYNVLQSIRLLSDTMVSFADHCVEGIEPNTARIKELLERSLMLVTALAPAIGYDNAARIAKTAHKNGTTLREEALASGLVSEEDYDRLVRAERMIAPQ
>NC_010740.1|WP_002966391.1|179066_179468_-|DoxX-family-protein
MSSITPKANGAATLIIRVFLSVLFIIAGYNKLTALDGTADYFASIGLPMPIVTAVVVGLIEFVGGLAILFGFKTRIAAVIVGLFTLGATLVAHMDFAEGMNLLIAQKNLAIAGGLFLLFLHGAGSLSIDARRG
>NC_010740.1|WP_002966392.1|177542_178781_-|sugar-MFS-transporter
MATSIPTNNPLHTETSSQKNYGFALTSLTLLFFMWGFITCLNDILIPHLKNVFQLNYTQSMLIQFCFFGAYFIVSLPAGQLVKRISYKRGIVVGLIVAAIGCALFIPAASYRVYALFLGALFVLASGVTILQVAANPYVTILGKPETAASRLTLTQAFNSLGTTVAPVFGAVLILSAATDATVNAEADAVRFPYLLLALAFTVLAIIFAILKPPDVQEDEPALSDKKEGSAWQYRHLVLGAIGIFVYVGAEVSVGSFLVNFLSDPTVAGLSETDAAHHVAYFWGGAMVGRFIGSAAMRYIDDGKALAFNAFVAIILLFITVATTGHIAMWSVLAIGLFNSIMFPTIFSLALHGLGSHTSQGSGILCLAIVGGAIVPLIQGALADAIGIHLAFLMPIICYAYIAFYGLIGSKS
>NC_010740.1|WP_002966393.1|176774_177470_+|ATP-phosphoribosyltransferase
MSVTLALPSKGRLKEKTLAVLEKAGYKVVLPDDDRNYRARVEGEDDLDILFLSASEIARELGYGSVDLGVTGEDLVRETLAHADERVAIEAQLGFGHADVVVAVPEVWRDVTTMADLDDVAADFRQRHGRRLRIATKYWRLTQQFFSQKHGIQVYRIVESLGATEGAPAAGSADMIVDITSTGSTLRANRLKVLEDGIILRSQACLVSARRSHTSRRVEEIAARIRAGLEI
>NC_010740.1|WP_002972153.1|175647_176778_+|ATP-phosphoribosyltransferase-regulatory-subunit
MVGSRTSPIFNALRVELNAREAELVEIPLIQPADPFLDMAGEDLRRRIFLTENENGDSLCLRPEFTIPVCRNHIALNAATPKRYAYLGEVFRQRRDGAAEFLQAGIEDLGAADEAASDARSLADALSCVKAIAPDAPLEIVLGDQSVFAGMLKALGLPQGWRKKLLRSFGDAHSMDLALAELTGTQRRDPLPESLAVLVAEGDEIGLARMLEAEMLEAGISPGAGRTPVEIARRLIEKEDLAATHFPAAALDLLRQFLAIRVSLDMAAVTLRAFAADNALDLGAVLQKFEARADAIAQAGIEMKDIIYDASFGRPLDYYTGLVYEIRDASNRQDGVLAGGGRYDRLLTMLGACEAIPGVGFSIWLDRLQALAGEKQ
>NC_010740.1|WP_002968826.1|174130_175639_+|histidine--tRNA-ligase
MADKADKMKARLPRGFVDRVPDDLRAAEKMMATIREVYDLYGFEPVETPLVEYTDALGKFLPDQDRPNEGVFSFQDDDEQWLSLRYDLTAPLARYVAENFETLPKPYRSYRNGWVFRNEKPGPGRFRQFMQFDADTVGAPNVSADAEMCMMMADTLERLGIQRGDYAIRVNNRKVLDGVLDAIGLEGEGNAAKRLNVLRAIDKLDKFGPEGVRLLLGKGRLDESGDFTKGAQLPEAAIEKVLAFTAAGGADGAQTIANLQAVVAGNAKGEEGVQELADMQALFFAGGYEGRVKIDPSVVRGLEYYTGPVFEAELLFDVTNEDGQKVVFGSVGGGGRYDGLVSRFRGEPVPATGFSIGVSRLMTALKNLGKLDVSDTVGPVVVLVMDKDTQNLGRYQKMVSDLRKAGIRAEMYVGGSGMKAQMKYADRRAAPCVVIQGSQEREAGEVQIKDLVEGKRLSAEIEDNVTWLESRPAQITVREDGLVDAVREILDAQARDRAEQSK
>NC_010740.1|WP_002966396.1|173402_174020_+|LysE-family-translocator
MDLMSLVAFAGILVVAAGTPGPKVGALVARVISRGHKGVFPFMFGLWLGDAVWLSLAVWGLSALAHTFQTAFLVLKYAGVAYLIYLSWKMWFAPVDEEADENTIPRQGEGKRLFLSALGVTLGNPKIMVFYLAILPTVVDITHVSLTGWVELLLVMFMVLAAVDTAWVVLAAQARKFLRSPRMMRLANRTSAGMMAGAAVAIAAR
>NC_010740.1|WP_002967189.1|172627_173284_+|DNA-3-methyladenine-glycosylase-I
MSDMAEARAGLVVGADGRTRCFWPGELPDYLAYHDNEWGVPVADDFRLFEKICLEGFQSGLSWLTILRKRENFRAAFDGFNFHRIATYDESDVERLLADKGIVRHRGKIVSVINNAGRAIELIEEKGSLAAYFWSFEPGAENRPAVVDYPTLVANPITATSTRISKDLKKRGWSFVGPTTVYAFMQAMGLVNDHIEGCHCRATIEKLRQNFKRPGKKL
>NC_010740.1|WP_002968994.1|170551_171379_-|aldo/keto-reductase
MTVPTVKLNDGNHIPQLGYGVWQISNDEAVSAVSEALKAGYRHIDTATIYGNEEGVGKAINGSGIARADIFLTTKLWNSDQGYESTLKAFDTSLKKLGTDYVDLYLIHWPMPSKDLFMETWRAFIKLKEEGRVKSIGVSNFRTADLERLIKESGVTPVLNQIELHPQFQQDELRLFHGKHDIATEAWSPLGQGKLLEDPTLKSIAEKHAKSVAQIILRWHIETGNIVIPKSITPARIKENFDIFDFTLNGTDHDAITKLDMADGRIGPNPSVFSA
>NC_010740.1|WP_002966386.1|183849_184146_-|co-chaperone-GroES
MADIKFRPLHDRVVVRRVESEAKTAGGIIIPDTAKEKPQEGEVVAAGAGARDEAGKLVPLDVKAGDRVLFGKWSGTEVKIGGEDLLIMKESDILGIVG
>NC_010740.1|WP_002972147.1|184626_185475_+|TIGR01459-family-HAD-type-hydrolase
MILPERLDDLTDRYDAIFCDVWGVVHNGETSFAPAIAALQRARAKGVTIILVTNSPRPHPGVVAQMSLLGVPEDAYDRVVTSGDVTRDLIAEGPRRIFHIGCERELAIYDGLDVELVEEFEAAGVVCTGLYDDEVETPEDYRELLQRLRARNLPFICANPDIMVERGPRLIWCAGALAREYGQLGGRTLIAGKPHRPIYEAALRAVESIRGGSVDKSRILGIGDGVLTDVKGAADFGLDVLYISGGVHAADYAVNGDLDMAKMEAFLEKHGHRPIASLHALV
>NC_010740.1|WP_002966383.1|185562_186552_+|bifunctional-riboflavin-kinase/FAD-synthetase
MKKSSFQRLTGTEGLPPALHDCVVAIGNFDGVHRGHQAVLERALELAERESRPAVVLTFEPHPRSFFKQDQPVDRLTDAAEKAEILRLMGFDAVMEQPFTAEFSQRSAEDFVQHILVEKLRASRVVTGYDFHFGKGRRGTPEFLCEAGKKAGFSVTLVDAFTDEGGMLVSSTRIRNLLSEGEVAEAAGLLGYRYRICGEVIHGKKLGRTLGFPTANMALAPQTSLKHGIYAVRFRLDDAMLYDGVASFGRRPTVDDEGAPLLETFLFDFSGDLYGKTAAVSFFGFLRGEVKFDGLDPLIDQMKQDEAQARALLADVRPISGLDRMLSFN
>NC_010740.1|WP_002966382.1|186895_189814_+|isoleucine--tRNA-ligase
MTDTTKIDYSKTLYLPQTEFPMRAGLPQREPLFVQRWEEMNLYKKLREQAKDRPLYVLHDGPPYANGNIHIGHALNKILKDVITRSFQMRGYNSNYVPGWDCHGLPIEWKIEEKYRAAGKNKDEVPINEFRKECREFASNWIKVQTEEFKRLAILGDFENPYTTMNFHAEARIAGELLKFAASGQLYRGSKPVMWSVVERTALAEAEVEYHDIESDMIWVKFPVAGEVATENDLSGSAVVIWTTTPWTIPGNRAVSYSSRIEYGLFEITEAENDFGPRPGERLVFADKLVEECCAKAKLQFKRLRSVSAEELGKIVLDHPLKGFGGGYEFVVPMLDGDHVTDDAGTGFVHTAPSHGREDFEAWMDNARQLEARGIDPNIPFPVGDDGFYTKDAPGFGPDREGGPARVIDDNGKKGDANKVVIEQLIAADKLFARGRLKHSYPHSWRSKKPVIFRNTPQWFVYMDKNLGDGTTLRSRALKAIDETRFVPAAGQTRLRSMIEGRPDWVLSRQRAWGVPICVFVDEEGNILQDDAVNKRIMDAFEKEGADAWFADGARERFLGARAGEGWTQVRDILDVWFDSGSTHTFTLEDRPDLKWPADVYLEGSDQHRGWFHSSLLESCGTRGRAPYNAVVTHGFTMDEHGKKMSKSLGNTVTPQDVIKESGADILRLWVMTTDYWEDQRLGKSIIQTNIDAYRKLRNTIRWMLGTLAHDEGENVAYADLPELERLMLHRLTELDELVRSGYDTFDFKRIARALVDFMNVELSAFYFDIRKDALYCDAPSSIRRKAALQTVREIFVRLTTWLAPMLPFTMEEAWLDRYPQSVSIHAEQFRPTPAEWRDDVLAEKWRKVRAVRRVVTGALELERADKRIGSSLEAAPVVYIADKSLSDSLEGLDFAEICITSGISVSDAAAPEGAFTLGDVKGVAVVPERAKGEKCARSWRYTTDVGADPEFPEVSARDAAALRELQALGKL
>NC_010740.1|WP_002971287.1|190005_190677_+|hypothetical-protein
MKIEGRVLVLMTALAGLSLSGCVSSPTYGTDKSAGAQLLDDVSNMASFGQGKKKERIDYKPRPDLVRPAPGDKGYLPAPQQSLASSSDPNWPESPEQRRKRVRDEITAHRDDPNYVSPVLQDAPVADNIRTALPRGNSRREDYASRTPTSDPAKVAALKAARAQQNQGSATTRRYLSEPPLAYRQPASTAAVGELGPDEAQKERERKKAASGSRGWRDYLPWN
>NC_010740.1|WP_002967192.1|191021_191582_+|cytochrome-b
MSSKTYIWDDRSGYGLVSRGFHWLMALLFLWQFASAILRVFAKDTPIYSFFWSAHFQLGFALLVLALLRGVWGLMNIHRRPHKDGAIGKLAVLGHLAIYVLMITIPSLALLRAYGSGRGFSFLGMPIFAKTDIQNAMLTAPANALHGPLGWALLAAIVGHVAMALVYHFALRDDTLRYMTGHGTPN
>NC_010740.1|WP_002966379.1|191635_192109_-|nucleoside-deaminase
MRKAASITKANSATPMDIALEEAHAAGERGEVPIGAVIVRDGEIIARAGNRTREFNDVTAHAEILTIRQAGEMLGSERLIDCDLYVTLEPCAMCAAAISFARIRRLYYGASDPKGGGIEHGGRFYTQPTCHHAPEIYPGFCEADARKILKDFFREKR
>NC_010740.1|WP_002966378.1|192249_193995_+|pseudouridine-synthase
MMAQGDAVTLLKGLYQMTTEDDNKGGKPPHGRKGHSDRPGRPDWDSRPRREGGDRDKPRKFGSRGAPVEEETSERIAKRLARAGIASRREAETMIAAGRIAVNGKVLESPAVNVKRTDIITVDGKPLRQTERTRLWLYHKPAGLVTTNRDPEGRPTVFEALPPEMPRVLSVGRLDINTEGLLLLTNDGGLSRVLELPSTGWLRRYRVRAHGKVTQQQLDELKNGIAVDGVFYGSVEAELERVQGANVWISIGLREGKNREVKNILGALGLTVGRLIRVSFGPFQLGDLEEGAVREIKGRTLRDQLGDKLIEESGADFDAPVLNEFSNAAVQGRTRREMEEGELPQEGERRRAPREREWISSTGERRRGREEKTEKVEPRRRGNANVWMAPGARPKGEKEAAKPARVEHQQPHRSAKFSGDLQMRPRRFSEEERGGEESGERRYKRPEGRFEREGGRPDNREKYEKHEGAGKERRPGKRERAELRNAEGQTTERGKGGFEGRKPGKPGGPRSEGRFGGADRDTRSGPRGSGPRGAGDGPRRGHDGKPGGKPGGKPTGRPGGKPGTKPGGGGRSGGGGADRRR
>NC_010740.1|WP_002966377.1|193975_194539_+|16S-rRNA-(guanine(966)-N(2))-methyltransferase-RsmD
MRIVGGKFRGRALVTPSTNAIRPTTDRTRESLFNILAHSFPDKVEGVRVLDLFAGTGALGLEALSRGARYATFVEESAEGRGILRQNIEALGLQGHTKILRRDACQLGIVGTMEPFDLVFADPPYGRRMGEKAFLSALQGGWLNPDALLVLEEDAQAALELDDRFAVREERNYGGTVIRLIELKAAS
>NC_010740.1|WP_002969286.1|194624_196169_+|insulinase-family-protein
MNTPHSGCLLLSTVLGFALALPLAGGAVRAEMQPAAPAETQPAPAAPAAPVAPAALPEIFRLDGVSNFTLPNGMQVVVIPDHRAPVVTQMVWYHVGAADEAPGVSGIAHFLEHLMFKGTKNHPAGEFSARIASIGGQENAFTSYDYTAYFQRVSPEALEMVMDFESDRMENLVLDEEAVKTEREVILEERRMRIDSNPGAMLMENTDAVLFYNHPYRKPVIGWQQEMEKLSLKNAIDFYNQYYTPNNATLVIAGDVTPERVRELAMKTWANVHKRAEVLLRERPQEPAKHAARVVTLHDERVSTPSFRISWLVPSYANEKRFANAKPGDAPALDLLSEILGGSQLSQLYQQLIVKQGIAAETGASYDGDALDDGTFSVYGVPRNGASLGDVEKAVAAQVDRIIRDGVTQAELDQARNRFLKAVIFARDSQTGMARIYGSALSVGQTVDDIQKWPDLIKSVTVDQIKDVARRYLVKDQAVTSYLLPPDTEAESARKKPNAPANDASASGAGGAIQ

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region	Region Position	Protein_number	Hit_taxonomy	Key_proteins	Att_site	Prophage annotation

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

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CRISPR-Cas detection and classification

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

544065 : 650225

101

Paenibacillus_phage(10.0%)

head,integrase,tail,holin,capsid,transposase,protease,portal

attL 642804:642818|attR 652696:652710

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_095833205.1\|544065_544822_+\|transposase	IS5 family transposase	A0A0N9SJT9	Paenibacillus_phage	6.1e-16	40.2
WP_002968716.1\|545193_546312_+	glycosyltransferase family 4 protein	NA	NA	NA	NA
WP_077281774.1\|547069_547222_-	hypothetical protein	NA	NA	NA	NA
WP_126358176.1\|547456_547819_-	hypothetical protein	NA	NA	NA	NA
WP_128832337.1\|547981_548744_+\|transposase	IS5 family transposase	A0A0N9SHJ4	Paenibacillus_phage	1.5e-22	41.7
WP_002975117.1\|548641_548959_-	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_002963688.1\|549569_550925_+	phosphomannomutase	NA	NA	NA	NA
WP_002963689.1\|550995_552420_+	mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase	A0A1V0SH58	Hokovirus	9.0e-53	30.8
WP_002963690.1\|552452_553625_+	AGE family epimerase/isomerase	NA	NA	NA	NA
WP_002969456.1\|553707_554817_+	glycosyltransferase family 4 protein	NA	NA	NA	NA
WP_109790518.1\|555165_555369_+	hypothetical protein	NA	NA	NA	NA
WP_002969848.1\|555475_557044_+	sugar ABC transporter ATP-binding protein	A0A2H4PQG7	Staphylococcus_phage	1.4e-14	25.3
WP_002963693.1\|557064_558066_+	ABC transporter permease	NA	NA	NA	NA
WP_002969455.1\|558144_559107_+	substrate-binding domain-containing protein	NA	NA	NA	NA
WP_002963695.1\|559164_560217_+	sugar phosphate isomerase/epimerase	NA	NA	NA	NA
WP_002969454.1\|560224_561322_+	Gfo/Idh/MocA family oxidoreductase	NA	NA	NA	NA
WP_002966715.1\|561363_562671_-	xylose isomerase	NA	NA	NA	NA
WP_002966716.1\|562717_564169_-	xylulokinase	NA	NA	NA	NA
WP_002963699.1\|564201_565233_-	LacI family DNA-binding transcriptional regulator	NA	NA	NA	NA
WP_014315809.1\|565494_565938_-	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_002969452.1\|565919_566489_-	AraC family transcriptional regulator	NA	NA	NA	NA
WP_002963701.1\|567026_568490_-	betaine-aldehyde dehydrogenase	NA	NA	NA	NA
WP_002966717.1\|568641_570324_-\|holin	choline dehydrogenase	A0A1V0S9M4	Catovirus	7.9e-40	30.6
WP_002969060.1\|570326_570923_-	transcriptional regulator BetI	NA	NA	NA	NA
WP_002963705.1\|571113_572136_+	asparaginase	NA	NA	NA	NA
WP_002963706.1\|572180_572651_+	GreA/GreB family elongation factor	NA	NA	NA	NA
WP_002963707.1\|572647_573037_-	type II toxin-antitoxin system death-on-curing family toxin	A0A1B3AYM0	Gordonia_phage	3.5e-07	44.6
WP_002963708.1\|573033_573264_-	AbrB/MazE/SpoVT family DNA-binding domain-containing protein	NA	NA	NA	NA
WP_002963709.1\|573324_574317_-	magnesium transporter CorA family protein	NA	NA	NA	NA
WP_002969451.1\|574472_574835_+	FadR family transcriptional regulator	NA	NA	NA	NA
WP_002969450.1\|574831_575152_+	FadR family transcriptional regulator	NA	NA	NA	NA
WP_002963712.1\|576483_576846_-	hypothetical protein	NA	NA	NA	NA
WP_002963713.1\|577181_578693_+	DUF853 domain-containing protein	A0A248XCZ8	Klebsiella_phage	1.4e-83	44.3
WP_002963714.1\|578882_579599_-	L,D-transpeptidase	NA	NA	NA	NA
WP_002971536.1\|579657_579900_+	hypothetical protein	NA	NA	NA	NA
WP_002963715.1\|579901_580555_-	haloacid dehalogenase type II	NA	NA	NA	NA
WP_002963716.1\|580777_581377_+	superoxide dismutase	Q56AR7	Bacillus_thuringiensis_phage	1.2e-38	42.6
WP_002963717.1\|581548_581884_-	hypothetical protein	NA	NA	NA	NA
WP_002963718.1\|582001_584110_-	S9 family peptidase	NA	NA	NA	NA
WP_002963720.1\|584682_585111_+	MucR family transcriptional regulator	A0A1P8VVG0	Erythrobacter_phage	1.0e-20	47.6
WP_002969861.1\|585318_585630_-	hypothetical protein	NA	NA	NA	NA
WP_002966719.1\|585810_586266_+	hypothetical protein	NA	NA	NA	NA
WP_002969449.1\|586262_587057_+	hypothetical protein	NA	NA	NA	NA
WP_002966720.1\|587167_588484_+	amidase	NA	NA	NA	NA
WP_002963725.1\|588524_588950_-	SufE family protein	NA	NA	NA	NA
WP_002963726.1\|589029_589479_-	hypothetical protein	NA	NA	NA	NA
WP_002969448.1\|589769_591599_+	HAMP domain-containing histidine kinase	W8CYF6	Bacillus_phage	4.7e-22	28.9
WP_002971535.1\|591573_592542_+	peptidoglycan-binding protein	NA	NA	NA	NA
WP_002963729.1\|592555_592903_+	DUF1491 family protein	NA	NA	NA	NA
WP_002969865.1\|592913_593990_-	DUF2336 domain-containing protein	NA	NA	NA	NA
WP_002963731.1\|594187_594730_-	hypothetical protein	NA	NA	NA	NA
WP_002963732.1\|594722_595334_-	DUF1214 domain-containing protein	NA	NA	NA	NA
WP_002969866.1\|595340_597515_-	penicillin-binding protein 1A	NA	NA	NA	NA
WP_002963734.1\|597854_598367_+	hypothetical protein	NA	NA	NA	NA
WP_002970982.1\|598305_599553_+	DNA-packaging protein	A0A1V0DY66	Dinoroseobacter_phage	4.9e-71	40.4
WP_002963736.1\|599584_600778_+\|portal	phage portal protein	W8ECU7	Geobacillus_phage	7.0e-67	40.0
WP_002963737.1\|600774_601152_+	hypothetical protein	NA	NA	NA	NA
WP_002963738.1\|601138_601807_+\|head,protease	HK97 family phage prohead protease	A0A2H4JAI0	uncultured_Caudovirales_phage	1.7e-30	41.1
WP_002966724.1\|601828_603103_+\|capsid	phage major capsid protein	Q8HAD2	Salmonella_phage	2.8e-82	43.6
WP_002963740.1\|603267_603834_+\|head,tail	phage head-tail connector protein	NA	NA	NA	NA
WP_002963741.1\|603830_604169_+\|head	phage head closure protein	NA	NA	NA	NA
WP_006072374.1\|604291_604699_+	DUF3168 domain-containing protein	NA	NA	NA	NA
WP_002963743.1\|604739_605153_+\|tail	phage major tail protein, TP901-1 family	NA	NA	NA	NA
WP_002963744.1\|605149_605491_+	gene transfer agent family protein	NA	NA	NA	NA
WP_002963745.1\|605534_605705_+\|tail	phage tail assembly chaperone	NA	NA	NA	NA
WP_002970984.1\|605709_606255_+\|tail	phage tail tape measure protein	A0A0S2SYD9	Pseudomonas_phage	2.8e-07	46.4
WP_002963747.1\|606257_606890_+	TIGR02217 family protein	A0A0B5A2K3	Paracoccus_phage	2.9e-48	47.6
WP_002963749.1\|607757_608180_+	C40 family peptidase	NA	NA	NA	NA
WP_002969445.1\|612111_612318_+	hypothetical protein	NA	NA	NA	NA
WP_002971526.1\|612479_612776_+	hypothetical protein	NA	NA	NA	NA
WP_002963753.1\|612854_613544_+	response regulator transcription factor	NA	NA	NA	NA
WP_002969444.1\|613618_614929_+	hypothetical protein	NA	NA	NA	NA
WP_002971524.1\|615022_615475_+	hypothetical protein	NA	NA	NA	NA
WP_002969443.1\|615575_616715_+	c-type cytochrome biogenesis protein CcmI	NA	NA	NA	NA
WP_002963757.1\|616711_617209_+	cytochrome c maturation protein CcmE	NA	NA	NA	NA
WP_002963758.1\|617228_619220_+	heme lyase CcmF/NrfE family subunit	NA	NA	NA	NA
WP_002963759.1\|619216_619693_+	cytochrome c-type biogenesis protein CcmH	NA	NA	NA	NA
WP_002963760.1\|619834_621376_+\|protease	DegQ family serine endoprotease	A0A1B1IT49	uncultured_Mediterranean_phage	1.7e-28	29.8
WP_002969442.1\|621469_622177_+	response regulator transcription factor	NA	NA	NA	NA
WP_002966726.1\|622173_623580_+	HAMP domain-containing histidine kinase	NA	NA	NA	NA
WP_002963763.1\|623702_626654_+	bifunctional [glutamine synthetase] adenylyltransferase/[glutamine synthetase]-adenylyl-L-tyrosine phosphorylase	NA	NA	NA	NA
WP_002966727.1\|626698_628810_-	O-antigen ligase family protein	NA	NA	NA	NA
WP_002969440.1\|629080_631432_-	PAS-domain containing protein	A0A1V0SGX0	Hokovirus	6.3e-27	34.8
WP_002968720.1\|631822_634474_-	aminopeptidase N	NA	NA	NA	NA
WP_002963767.1\|634699_635659_+	DMT family transporter	NA	NA	NA	NA
WP_002970986.1\|635663_636920_-	MFS transporter	NA	NA	NA	NA
WP_002963769.1\|637081_637954_-	uracil-DNA glycosylase	NA	NA	NA	NA
WP_002963770.1\|638342_640034_+	electron transfer flavoprotein-ubiquinone oxidoreductase	NA	NA	NA	NA
WP_002969439.1\|640149_641118_-	endonuclease/exonuclease/phosphatase family protein	NA	NA	NA	NA
WP_002963772.1\|641286_642789_-	AMP nucleosidase	NA	NA	NA	NA
642804:642818	attL	NA	NA	NA	NA
WP_002966730.1\|642829_642997_-	hypothetical protein	NA	NA	NA	NA
WP_002971518.1\|642993_643161_-	hypothetical protein	NA	NA	NA	NA
WP_002963775.1\|643355_644066_+	glutathione S-transferase N-terminal domain-containing protein	NA	NA	NA	NA
WP_002963776.1\|644124_644472_-	DUF2147 domain-containing protein	NA	NA	NA	NA
WP_002969438.1\|644468_644702_-	hypothetical protein	NA	NA	NA	NA
WP_002963778.1\|644971_645229_+	hypothetical protein	NA	NA	NA	NA
WP_002963779.1\|645288_646059_-	YitT family protein	NA	NA	NA	NA
WP_002963780.1\|646715_647366_+	hypothetical protein	NA	NA	NA	NA
WP_002963781.1\|647410_647785_-	DUF423 domain-containing protein	NA	NA	NA	NA
WP_002963782.1\|647802_648936_-	pyridoxal phosphate-dependent aminotransferase	A0A1X7QHI1	Faustovirus	9.1e-16	23.9
WP_002967515.1\|649298_650225_-\|integrase	site-specific integrase	A0A076YL28	Mesorhizobium_phage	2.9e-28	36.3
652696:652710	attR	NA	NA	NA	NA

DBSCAN-SWA_2

874188 : 886116

uncultured_Mediterranean_phage(90.0%)

tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_002968731.1\|874188_875040_+	segregation/condensation protein A	A0A1B1IVW1	uncultured_Mediterranean_phage	4.4e-31	33.5
WP_002964011.1\|875032_875758_+	SMC-Scp complex subunit ScpB	A0A1B1IVT7	uncultured_Mediterranean_phage	1.5e-43	45.7
WP_002964012.1\|875903_876122_+	twin-arginine translocase TatA/TatE family subunit	A0A1B1IVR9	uncultured_Mediterranean_phage	1.5e-07	65.1
WP_002969412.1\|876232_876814_+	twin-arginine translocase subunit TatB	NA	NA	NA	NA
WP_002964014.1\|876810_877635_+	twin-arginine translocase subunit TatC	A0A1B1IVR7	uncultured_Mediterranean_phage	9.8e-44	41.1
WP_002964015.1\|877711_878995_+\|tRNA	serine--tRNA ligase	A0A1B1IVT2	uncultured_Mediterranean_phage	1.2e-104	47.2
WP_002966786.1\|879143_879911_+	5'/3'-nucleotidase SurE	A0A1B1ITZ2	uncultured_Mediterranean_phage	1.0e-39	40.2
WP_002964017.1\|879907_880576_+	protein-L-isoaspartate(D-aspartate) O-methyltransferase	A0A1B1IU40	uncultured_Mediterranean_phage	4.2e-13	37.8
WP_002964018.1\|880720_880906_+	hypothetical protein	NA	NA	NA	NA
WP_002964019.1\|880954_882253_+	peptidoglycan DD-metalloendopeptidase family protein	Q8SBN9	Clostridium_phage	1.0e-18	41.1
WP_002964020.1\|882301_883168_-	ATP-binding protein	NA	NA	NA	NA
WP_002964021.1\|883328_883670_+	preprotein translocase subunit YajC	A0A1B1IVR5	uncultured_Mediterranean_phage	9.1e-12	40.2
WP_002969969.1\|883788_886116_+	protein translocase subunit SecDF	A0A1B1IVP7	uncultured_Mediterranean_phage	6.2e-51	43.5

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. NC_010740

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Click the colored protein region to show detailed information

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection

2. NC_010742

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection