CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NC_010380	Streptococcus pneumoniae Hungary19A-6, complete sequence	1 crisprs	DEDDh,cas3,DinG,RT	0	0	10	0

Results visualization

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CRISPR-Cas detection and classification

Crispr_ID: NC_010380_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_010380_1

174457-174552

Orphan

Consensus_repeat	Method
AATGTGTAAGATTTTTATATATAA	CRISPRCasFinder

1 spacers

The CRISPR arrays of NC_010380_1

>merge|NC_010380|1|174457-174552|CRISPRCasFinder
AATGTGTAAGATTTTTATATATAATTTTTCTACACATACATTGTACATCTAAAAGAAAGCCCTGTCAAGAGAAATGTGTAAAATTTTTATATATAA

>NC_010380|1|1|174457-174552|CRISPRCasFinder
AATGTGTAAGATTTTTATATATAA	TTTTTCTACACATACATTGTACATCTAAAAGAAAGCCCTGTCAAGAGA
AATGTGTAAAATTTTTATATATAA

Protein	Signature genes	Signature genes Name	Protein_function
NC_010380.1\|WP_078136768.1\|184339_184633_+\|lactococcin-972-family-bacteriocin	unknown	unknown	gnl\|CDD\|370615
NC_010380.1\|WP_001818684.1\|164770_165031_+\|hypothetical-protein	unknown	unknown	unknown
NC_010380.1\|WP_001035700.1\|177000_178851_+\|polysaccharide-biosynthesis-protein	unknown	unknown	gnl\|CDD\|224011
NC_010380.1\|WP_000096198.1\|175801_176959_+\|glycosyltransferase-family-2-protein	unknown	unknown	gnl\|CDD\|133016
NC_010380.1\|WP_001108797.1\|183384_183972_+\|hypothetical-protein	unknown	unknown	unknown
NC_010380.1\|WP_001030014.1\|169395_170382_+\|rhodanese-related-sulfurtransferase	unknown	unknown	gnl\|CDD\|234663
NC_010380.1\|WP_000273864.1\|174112_174439_-\|PadR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|224609
NC_010380.1\|WP_000714582.1\|165524_166454_+\|sugar-ABC-transporter-permease	unknown	unknown	gnl\|CDD\|226666
NC_010380.1\|WP_000836450.1\|181559_182147_+\|LysM-peptidoglycan-binding-domain-containing-protein	unknown	unknown	gnl\|CDD\|212030
NC_010380.1\|WP_001233696.1\|172628_173540_-\|DUF4097-domain-containing-protein	unknown	unknown	gnl\|CDD\|372574
NC_010380.1\|WP_001809441.1\|164984_165206_+\|hypothetical-protein	unknown	unknown	unknown
NC_010380.1\|WP_000808456.1\|171501_172566_-\|membrane-protein	unknown	unknown	gnl\|CDD\|370966
NC_010380.1\|WP_000800407.1\|167648_169124_+\|DUF3502-domain-containing-protein	unknown	unknown	gnl\|CDD\|378792
NC_010380.1\|WP_000744892.1\|174577_175744_-\|CynX/NimT-family-MFS-transporter	unknown	unknown	gnl\|CDD\|340897
NC_010380.1\|WP_001268178.1\|182198_183062_-\|helix-turn-helix-transcriptional-regulator	unknown	unknown	gnl\|CDD\|238045
NC_010380.1\|WP_000200894.1\|179111_179744_-\|HAD-family-hydrolase	unknown	unknown	gnl\|CDD\|319798
NC_010380.1\|WP_000838917.1\|180646_181318_-\|L-serine-ammonia-lyase,-iron-sulfur-dependent,-subunit-beta	unknown	unknown	gnl\|CDD\|224674
NC_010380.1\|WP_000198697.1\|173532_174126_-\|DUF1700-domain-containing-protein	unknown	unknown	gnl\|CDD\|227053
NC_010380.1\|WP_000500040.1\|179765_180638_-\|L-serine-ammonia-lyase,-iron-sulfur-dependent,-subunit-alpha	unknown	unknown	gnl\|CDD\|129801
NC_010380.1\|WP_001075102.1\|166467_167391_+\|carbohydrate-ABC-transporter-permease	unknown	unknown	gnl\|CDD\|223472

Protein	Function_ID	Function_description	E-value
NC_010380.1\|WP_078136768.1\|184339_184633_+\|lactococcin-972-family-bacteriocin	gnl\|CDD\|370615	pfam09683, Lactococcin_972, Bacteriocin (Lactococcin_972). These sequences represent bacteriocins related to lactococcin. Members tend to be found in association with a seven transmembrane putative immunity protein.	2.24123e-21
NC_010380.1\|WP_000838917.1\|180646_181318_-\|L-serine-ammonia-lyase,-iron-sulfur-dependent,-subunit-beta	gnl\|CDD\|224674	COG1760, SdaA, L-serine deaminase [Amino acid transport and metabolism].	1.19126e-88
NC_010380.1\|WP_001035700.1\|177000_178851_+\|polysaccharide-biosynthesis-protein	gnl\|CDD\|224011	COG1086, COG1086, Predicted nucleoside-diphosphate sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism].	0
NC_010380.1\|WP_000096198.1\|175801_176959_+\|glycosyltransferase-family-2-protein	gnl\|CDD\|133016	cd02525, Succinoglycan_BP_ExoA, ExoA is involved in the biosynthesis of succinoglycan. Succinoglycan Biosynthesis Protein ExoA catalyzes the formation of a beta-1,3 linkage of the second sugar (glucose) of the succinoglycan with the galactose on the lipid carrie. Succinoglycan is an acidic exopolysaccharide that is important for invasion of the nodules. Succinoglycan is a high-molecular-weight polymer composed of repeating octasaccharide units. These units are synthesized on membrane-bound isoprenoid lipid carriers, beginning with galactose followed by seven glucose molecules, and modified by the addition of acetate, succinate, and pyruvate. ExoA is a membrane protein with a transmembrance domain at c-terminus.	3.24889e-109
NC_010380.1\|WP_001030014.1\|169395_170382_+\|rhodanese-related-sulfurtransferase	gnl\|CDD\|234663	PRK00142, PRK00142, rhodanese-related sulfurtransferase.	0
NC_010380.1\|WP_000273864.1\|174112_174439_-\|PadR-family-transcriptional-regulator	gnl\|CDD\|224609	COG1695, COG1695, Predicted transcriptional regulators [Transcription].	3.12912e-19
NC_010380.1\|WP_000714582.1\|165524_166454_+\|sugar-ABC-transporter-permease	gnl\|CDD\|226666	COG4209, LplB, ABC-type polysaccharide transport system, permease component [Carbohydrate transport and metabolism].	3.01638e-143
NC_010380.1\|WP_000836450.1\|181559_182147_+\|LysM-peptidoglycan-binding-domain-containing-protein	gnl\|CDD\|212030	cd00118, LysM, Lysin Motif is a small domain involved in binding peptidoglycan. LysM, a small globular domain with approximately 40 amino acids, is a widespread protein module involved in binding peptidoglycan in bacteria and chitin in eukaryotes. The domain was originally identified in enzymes that degrade bacterial cell walls, but proteins involved in many other biological functions also contain this domain. It has been reported that the LysM domain functions as a signal for specific plant-bacteria recognition in bacterial pathogenesis. Many of these enzymes are modular and are composed of catalytic units linked to one or several repeats of LysM domains. LysM domains are found in bacteria and eukaryotes.	1.09004e-14
NC_010380.1\|WP_001233696.1\|172628_173540_-\|DUF4097-domain-containing-protein	gnl\|CDD\|372574	pfam13349, DUF4097, Putative adhesin. This has a putative all-beta structure with a twenty-residue repeat with a highly conserved repeating GD, gly-asp, motif. It may form part of a bacterial adhesin.	9.9455e-40
NC_010380.1\|WP_000808456.1\|171501_172566_-\|membrane-protein	gnl\|CDD\|370966	pfam10310, DUF5427, Family of unknown function (DUF5427). This is a domain of unknown function. Family members found in Saccharomyces cerevisiae, are synthetic lethal with genes involved in maintenance of telomere capping. However, experimental evidence is yet to verify the exact function of family members and the domain.	5.27948e-06
NC_010380.1\|WP_000800407.1\|167648_169124_+\|DUF3502-domain-containing-protein	gnl\|CDD\|378792	pfam12010, DUF3502, Domain of unknown function (DUF3502). This presumed domain is functionally uncharacterized. This domain is found in bacteria. This domain is about 140 amino acids in length. This domain is found associated with pfam01547.	4.24398e-44
NC_010380.1\|WP_000744892.1\|174577_175744_-\|CynX/NimT-family-MFS-transporter	gnl\|CDD\|340897	cd17339, MFS_NIMT_CynX_like, 2-nitroimidazole and cyanate transporters and similar proteins of the Major Facilitator Superfamily of transporters. This family is composed of Escherichia coli 2-nitroimidazole transporter (NIMT) and cyanate transport protein CynX, and similar proteins. NIMT, also called YeaN, confers resistance to 2-nitroimidazole, the antibacterial and antifungal antibiotic, by mediating the active efflux of this compound. CynX is part of an active transport system that transports exogenous cyanate into E. coli cells. The NIMT/CynX-like family belongs to the Major Facilitator Superfamily (MFS) of membrane transport proteins, which are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	7.61054e-125
NC_010380.1\|WP_000200894.1\|179111_179744_-\|HAD-family-hydrolase	gnl\|CDD\|319798	cd04302, HAD_5NT, haloacid dehalogenase (HAD)-like 5'-nucleotidases similar to the Pseudomonas aeruginosa PA0065. 5'-nucleotidases dephosphorylate nucleoside 5'-monophosphates to nucleosides and inorganic phosphate. Purified Pseudomonas aeruginosa PA0065 displayed high activity toward 5'-UMP and 5'-IMP, significant activity against 5'-XMP and 5'-TMP, and low activity against 5'-CMP. This family belongs to the haloacid dehalogenase-like (HAD) hydrolases, a large superfamily of diverse enzymes that catalyze carbon or phosphoryl group transfer reactions on a range of substrates, using an active site aspartate in nucleophilic catalysis. Members of this superfamily include 2-L-haloalkanoic acid dehalogenase, azetidine hydrolase, phosphonoacetaldehyde hydrolase, phosphoserine phosphatase, phosphomannomutase, P-type ATPases and many others. HAD hydrolases are found in all three kingdoms of life, and most genomes are predicted to contain multiple HAD-like proteins. Members possess a highly conserved alpha/beta core domain, and many also possess a small cap domain, the fold and function of which is variable. HAD hydrolases are sometimes referred to as belonging to the DDDD superfamily of phosphohydrolases.	1.25443e-98
NC_010380.1\|WP_001268178.1\|182198_183062_-\|helix-turn-helix-transcriptional-regulator	gnl\|CDD\|238045	cd00093, HTH_XRE, Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators.	1.14006e-10
NC_010380.1\|WP_000198697.1\|173532_174126_-\|DUF1700-domain-containing-protein	gnl\|CDD\|227053	COG4709, COG4709, Predicted membrane protein [Function unknown].	7.13921e-64
NC_010380.1\|WP_000500040.1\|179765_180638_-\|L-serine-ammonia-lyase,-iron-sulfur-dependent,-subunit-alpha	gnl\|CDD\|129801	TIGR00718, Probable_L-serine_dehydratase_alpha_chain, L-serine dehydratase, iron-sulfur-dependent, alpha subunit. This enzyme is also called serine deaminase. L-serine dehydratase converts serine into pyruvate in the gluconeogenesis pathway from serine. This model describes the alpha chain of an iron-sulfur-dependent L-serine dehydratase, found in Bacillus subtilis. A fairly deep split in a UPGMA tree separates members of this family of alpha chains from the homologous region of single chain forms such as found in Escherichia coli. This family of enzymes is not homologous to the pyridoxal phosphate-dependent threonine deaminases and eukaryotic serine deaminases. [Energy metabolism, Amino acids and amines, Energy metabolism, Glycolysis/gluconeogenesis].	1.44295e-105
NC_010380.1\|WP_001075102.1\|166467_167391_+\|carbohydrate-ABC-transporter-permease	gnl\|CDD\|223472	COG0395, UgpE, ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism].	5.04007e-69

>NC_010380.1|WP_000273864.1|174112_174439_-|PadR-family-transcriptional-regulator
MYFPTSSALIEFLILAVLEQGDSYGYEISQTIKLIANIKESTLYPILKKLEGNSFLTTYSREFQGRMRKYYSLTNGGIEQLLTLKDEWTLYTDTINGIIEGSIRHDKN
>NC_010380.1|WP_000198697.1|173532_174126_-|DUF1700-domain-containing-protein
MTRTEYLTQLELYLKKLPEADRIEAMDYFRELFDDAGVEGEEELIASLGTPKEVAHEVLSNLLDKKINEAPAQKNNRQILHIALLALLAAPIGIPLGIAILVTLFAILVAALTVILAFFAVSILGIIGGFLFLVESFTVLAQAKSAFILIFGSGLLAIGASSLVLLGISYVARFFGLLIVRLVQFVLKKGKRGNQHA
>NC_010380.1|WP_001233696.1|172628_173540_-|DUF4097-domain-containing-protein
MRKWTKGFLIFGVVTTVIGFILLFVGIQSDGIKSLLSMSKEPVYDSRTEKLTFGKEVENLEITLHQHTLTITDSFDDQIHISYHPSLSAHHDLITNQNDRTLSLTDKKLSETPFLSSGIGGILHIASSYSSRFEEVILRLPKGRTLKGINISANRGQTTIINASLENATLNTNSYILRIEGSRIKNSKLTTPNIVNIFDTVLTDSQLESTENHFHAENIQVHGKVELTAKDYLRIILDQKESQRINWDISSNYGSIFQFTREKPESRGTELSNPYKTEKTDVKDQLIARSDDNIDLISTPSRR
>NC_010380.1|WP_000808456.1|171501_172566_-|membrane-protein
MKQEWFESNDFVKTTSKNKPEEQAQEVADKAEETIADLDTPIGKNTQVEEEVSQAEVELESQQEEKIETPEGGEARTEIEEKKASNSTEEEPDLSKETEKVTIAEESQEALPQQKATTKEPLLISKSLESPYIPDQAPKSRDKWKEQVLDFWSWLVEAIKSPTSKLETSITHSYTAFLLLILFSASSFFFSIYHIKHAYYGHIASINSRFPEQLAPLTLFSIISILVATTLFFFSFLLGSFVVRRFIHQEKDWTLDKVLQQYSQLLAIPIFLTAIASFFAFFDSLRFTALLCVISIGIILLASLHIITRPSQASETDSFYQLFLSVLVNGVIILLFFVAEVALIGDYLRILAFL
>NC_010380.1|WP_001030014.1|169395_170382_+|rhodanese-related-sulfurtransferase
MAKDIRVLLYYLYTPIENAEQFAADHLAFCKSIGLKGRILVADEGINGTVSGDYETTQKYMDYVHSLPGMEDLWFKIDEENEQAFKKMFVRYKKEIVHLGLEDNDFDNDINPLETTGAYLSPKEFKEALLDKDTVVLDTRNDYEYDLGHFRGAIRPDIRNFRELPQWVRDNKEKFMDKRVVVYCTGGVRCEKFSGWMVREGYKDVGQLHGGIATYGKDPEVQGELWDGKMYVFDERIAVDVNHVNPTIVGKDWFDGTPCERYVNCGNPFCNRRILTSEENEDKYLRGCSHECRVHPRNRYVSKNELTQAEVIERLAAIGESLDQAATV
>NC_010380.1|WP_000800407.1|167648_169124_+|DUF3502-domain-containing-protein
MKNWKKYAFASASVVALAAGLAACGNLTGNSKKAADSGDKPVIKMYQIGDKPDNLDELLANANKIIEEKVGAKLDIQYLGWGDYGKKMSVITSSGENYDIAFADNYIVNAQKGAYADLTELYKKEGKDLYKALDPAYIKGNTVNGKIYAVPVAANVASSQNFAFNGTLLAKYGIDISGVTSYETLEPVLKQIKEKAPDVVPFAIGKVFIPSDNFDYPVANGLPFVIDLEGDTTKVVNRYEVPRFKEHLKTLHKFYEAGYIPKDVATSDTSFDLQQDTWFVREETVGPADYGNSLLSRVANKDIQIKPITNFIKKNQTTQVANFVISNNSKNKEKSMEILNLLNTNPELLNGLVYGPEGKNWEKIEGKENRVRVLDGYKGNTHMGGWNTGNNWILYINENVTDQQIENSKKELAEAKESPALGFIFNTDNVKSEISAIANTMQQFDTAINTGTVDPDKAIPELMEKLKSEGAYEKVLNEMQKQYDEFLKNKK
>NC_010380.1|WP_001075102.1|166467_167391_+|carbohydrate-ABC-transporter-permease
MAKKKIKKEKIDNVGIHSFSKKADIFFSIISGLIALSCILPFVFVIIISVTDEKSLLQYGYSFFPSQFGLDGFEFLAQFKDKILQALFISVFVTVVGTLTNVFITTTYAYAISRTTFKYRRFFTIFVLLSMLFNAGLVPGYIMVTRVLQLGDTVWALIVPMLLSPFNIILMRSFFKKTIPEAILESARIDGASEARIFFQICLPLSLPGIATITLLTALGFWNDWFNALLYIKSDNLYPLQYLLMQIQQNMDYIAKAVGLTGQLGVALPKETGRMAMVVVATLPIAILYPFFQRYFVKGLTIGGVKE
>NC_010380.1|WP_000714582.1|165524_166454_+|sugar-ABC-transporter-permease
MKKFSKTLRDNWIFLLMVLPGALWLILFFYIPVFGNVVAFKDYHMTSNGFIDSIINSKWVGLDNFRFLFSSRDAFIITRNTVLYNLGFIFLGLVVSVGIAIILSELRSKRMVKIFQTSMLFPYFLSWVIISFFTDAFLNIDKGVFNHLLESLGLKEVNFYADLGIWPYLLLFLGIWKGFGYSSVMYYATIMGIDPTYYEAATVDGASKWQRIRNVTIPQLTPLVTVLTILAVGNIFRADFGLFYQIPHNAGQLYNVTNVLDVYVFNGLTQTADIGMAAAAGLYQSVVGLILVILSNLLARRVDPNSALF
>NC_010380.1|WP_001809441.1|164984_165206_+|hypothetical-protein
MSLQIKLKKLAKELSKLLKDSNLETVDKDVLENSQKELQKAVLFLADEKGSEHTEAEVIDNLKEVIAKLKANA
>NC_010380.1|WP_001818684.1|164770_165031_+|hypothetical-protein
MTGVSNPTTDSARLVLAEAKKALADDSLTEQGLRDILQTVKDAIASLESIKESQSATKDGGQTAGKETAGEDESANQTQEISQGIK
>NC_010380.1|WP_000744892.1|174577_175744_-|CynX/NimT-family-MFS-transporter
MKKQSLFFVPGIILIGVSLRTPFTVLPIILGNISQGLEVEVSSLGVLTSLPLLMFTLFSPFSTQLAQKIGLEHLFTYSLFFLTIGSLIRLINLPLLYLGTLMVGASVAVINVLLPSLIQANQPKKIGFLTTLYVTSMGIATALASYLAVPITQASSWKGLILLLTLLCLATFLVWLPNHRYNHRLAPQTKQKSQIKVMRNKQVWAIIIFSGFQSLIFYTAMTWLPTMSIHAGLSSHEAGLLTSILSLISIPFSMTIPSLTTSLSTRNRQLMLTLVSLAGVVGISMLFFPINNFIYWLAIHLLIGTATSALFPYLMVNFSLKTSAPEKTAQLSGLSQTGGYILAAFGPTLFGYSFDLFHSWVPAVAALLLIDILMTVALFTVDRADKIL
>NC_010380.1|WP_000096198.1|175801_176959_+|glycosyltransferase-family-2-protein
MSSKVSGFQDKNGKVLKIMIEWWKEKFRRVVVTQNVESLLVSIVISAYNEEKYLPGLIEDLKNQTYPKENIEILFINAMSTDGTTAIIQQFIKEDTEFNSIRLYNNPKKNQASGFNLGVKHSVGDLILKIDAHSKVTETFVMNNVAIIQQGEFVCGGPRPTIVEGKGKWAETLHLVEENMFGSSIANYRNSSEDRYVSSIFHGMYKREVFQKVGLVNEQLGRTEDNDIHYRIREHGYKIRYSPSILSYQYIRPTFKKMLHQKYSNGLWIGLTSHVQFKCLSLFHYVPCLFVLSLVFSLALLPITFVFITLLLGAYFLLLSLLTLLTLLKHKNGFLIVMPFLLFSIHFAYGFGTIVGLIRGFKWKKEYKGTIIYLDKISQINQNML
>NC_010380.1|WP_001035700.1|177000_178851_+|polysaccharide-biosynthesis-protein
MNKKLTDYVIDLVEILNKQQKQVFWGIFDIFSMVVSIIVSYILFYGLINPAPVDYIIYTSLAFLFYQLMIGFWGLNASISRYSKITDFMKIFFGVTASSVLSYSICYAFLPLFSIRFIILFILLSTFLILLPRITWQLIYSRRKKGSGDGEHRRTFLIGAGDGGALFMDSYQHPTSELELVGILDKDSKKKGQKLGGIPVLGSYDNLPELAKRHQIERVIVAIPSLDPSEYERILQMCNKLGVKCYKMPKVETVVQGLHQAGTGFQKIDITDLLGRQEIRLDESRLGAELTGKTILVTGAGGSIGSEICRQVSRFNPERIVLLGHGENSIYLVYHELIRKFQGIDYVPVIADIQDYDRLLQVFEQYKPAIVYHAAAHKHVPMMERNPKEAFKNNIRGTYNVAKAVDEAKVSKMVMISTDKAVNPPNVMGATKRVAELIVTGFNQRSQSTYCAVRFGNVLGSRGSVIPVFERQIAEGGPVTVTDFRMTRYFMTIPEASRLVIHAGAYAKDGEVFILDMGKPVKIYDLAKKMVLLSGHTESEIPIVEVGIRPGEKLYEELLVSTELVDNQVMDKIFVGKVNVMPLESINQKIGEFRTLSGDELKQAIIAFANQTTHIE
>NC_010380.1|WP_000200894.1|179111_179744_-|HAD-family-hydrolase
MTSITAIFFDLDGTLVDSSIGIHNAFTYTFKELGVPSPDAKTIRGFMGPPLESSFATCLSKDQISEAVQIYRSYYKAKGIYEAQLFPQIIDLLEELSSSYPLYITTTKNTSTAQDMAKNLEIHHFFDGIYGSSPEAPHKADVIHQALQTHQLAPEQAIIIGDTKFDMLGARETGIQKLAVTWGFGEQADLLNYQPDYIAHKPLEVLAYFQ
>NC_010380.1|WP_000500040.1|179765_180638_-|L-serine-ammonia-lyase,-iron-sulfur-dependent,-subunit-alpha
MFYSIKELVEQADLDFQGNVAELMITTEFELTGREREEVFLLMERNLEVMKASVQLGLNENKSRSGLTGGDAAKLDHYIKNEKTLSDYTILSAARNAIAVNEHNAKMGLVCATPTAGSAGCLPSVLTAAIEKLDLSHEQQLDFLFAAGAFGLVIANNASISGAEGGCQAEVGSASAMSAAALTLAAGGTPYQASQAIAFVIKNMLGLICDPVAGLVEVPCVKRNAMGASFAFIAADMALAGIESKIPVDEVIDAMYQVGASMPTAFRETAEGGLATTPTGRRLQKEIFGE
>NC_010380.1|WP_000838917.1|180646_181318_-|L-serine-ammonia-lyase,-iron-sulfur-dependent,-subunit-beta
MKSLRFQSVFDIIGPVMIGPSSSHTAGAVRIGKIVSSIFDDTPTEVEFQLFNSFAKTYRGHGTDLALVAGILGMNTDDPEIPNSLEIAHKRGIKIVWTIQKDSNAPHPNTTKITVKNAHKTISVTGISIGGGNIQVTELNGFAVSLNMNTPTIIIVHQDIPGMIALVTEALSRYGINIAQMNVTREKAGEKAIMIIEVDSRNCDEAIEEIRKIPHLHNVNFFK
>NC_010380.1|WP_000836450.1|181559_182147_+|LysM-peptidoglycan-binding-domain-containing-protein
MKSITKKIKATLAGVAALFAVFAPSFVSAQESSTYTVKEGDTLSEIAETHNTTVEKLAENNHIDNIHLIYVGQELVIDGPVAPVATPAPATYAAPAAQDETVSAPVAETPVVSETVVSTVSGSEAEAKEWIAQKESGGSYTATNGRYIGRYQLTDSYLNGDYSAENQERVADAYVAGRYGSWTAAKNFWLNNGWY
>NC_010380.1|WP_001268178.1|182198_183062_-|helix-turn-helix-transcriptional-regulator
MRYDFGKVYKEIRESKGLTQEEVCGNVISRTSLSKIESGKATPKYENMEFLLRQINMSFEEFDYICHLYQPSQRTEIMQTYLNMTSIIGSNSLVHFFETCQDYLKTHHDLPIEEIRDMLEIVIHIRQHGTEQLSNQVKQTVTKLWEKIEKQDTWYENDLKILNTILFSFPIDHLHLITGKILQRLEVYKNYQHLYDLRMAILLNLSTIYLYHQDKNMCRQICYTLLEDAKKKKHYDRLAICYVRIGICRDDARLIQKGFSLLELTEETSMLSHLKKEVEIYSQPKEI
>NC_010380.1|WP_001108797.1|183384_183972_+|hypothetical-protein
MNYNLKYLLSGIVVLVFIGFLVWMRYFNQRKEEEHSDVSFEARLDSEVKTLYKQLGLGEEPHYFLAYRYLHPWFDLAILPPTVEIFLTKIALVMVTPDELLIRNLGNGLTFTSEHHRDLRQGLIRIPKSEMKEFEIRNWKKFFVFGDFLTIKTSQHSYYLQVRDDGLQKGSLSTKHFSDLKSQDFLGLLTDKRTF
>NC_010380.1|WP_078136768.1|184339_184633_+|lactococcin-972-family-bacteriocin
MIGEINHEKIGVASLMVCSILASTSVLAVWVDGGQWNYGVGWSGNFGYSDYLHSTRSHTATVKDGNKFSKDCAEAEAWARASIFKFPPTGMEYFYGF

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

4381 : 116995

116

Streptococcus_phage(91.4%)

bacteriocin,integrase,tail,terminase,holin,portal,tRNA,head,protease,capsid

attL 21165:21224|attR 104284:104355

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000163932.1\|4381_4951_+\|tRNA	aminoacyl-tRNA hydrolase	NA	NA	NA	NA
WP_000258108.1\|4951_8461_+	transcription-repair coupling factor	NA	NA	NA	NA
WP_001234978.1\|8518_8785_+	RNA-binding S4 domain-containing protein	NA	NA	NA	NA
WP_000041909.1\|8777_9146_+	septum formation initiator family protein	NA	NA	NA	NA
WP_001224760.1\|9265_10534_+	serine hydrolase	NA	NA	NA	NA
WP_001208981.1\|10530_11808_+\|tRNA	tRNA lysidine(34) synthetase TilS	A7K9Y8	Acanthocystis_turfacea_chlorella_virus	2.5e-06	24.1
WP_000892184.1\|11811_12354_+	hypoxanthine phosphoribosyltransferase	A0A218MMB5	uncultured_virus	2.7e-10	28.9
WP_000744551.1\|12369_14328_+	ATP-dependent metallopeptidase FtsH/Yme1/Tma family protein	H8ZJI5	Ostreococcus_tauri_virus	2.4e-109	45.8
WP_000588897.1\|14449_14929_+	sigma-70 family RNA polymerase sigma factor	NA	NA	NA	NA
21165:21224	attL	NA	NA	NA	NA
WP_000939545.1\|21501_21738_+	hypothetical protein	NA	NA	NA	NA
WP_000205044.1\|21968_23255_+	adenylosuccinate synthase	L7Y4J5	Megavirus	2.7e-72	37.1
WP_000876728.1\|23496_24645_-\|integrase	site-specific integrase	A0A1S5SCM1	Streptococcus_phage	4.6e-217	99.7
WP_000539947.1\|24815_25616_-	restriction endonuclease	A0A1S5SDT5	Streptococcus_phage	1.1e-113	99.6
WP_000069476.1\|25742_26498_-	helix-turn-helix transcriptional regulator	A0A1S5SD15	Streptococcus_phage	1.2e-141	100.0
WP_001171134.1\|26671_26878_+	helix-turn-helix transcriptional regulator	A0A1S5SCX8	Streptococcus_phage	1.1e-31	100.0
WP_000289447.1\|27185_27863_-	DUF4145 domain-containing protein	A0A1S5SCM5	Streptococcus_phage	7.6e-127	100.0
WP_001002349.1\|27917_28631_+	hypothetical protein	A0A1S5SCR9	Streptococcus_phage	1.4e-134	100.0
WP_000370959.1\|28643_28901_+	hypothetical protein	A0A1S5SEV6	Streptococcus_phage	1.2e-43	100.0
WP_000462823.1\|28986_29307_+	hypothetical protein	A0A1S5SCK7	Streptococcus_phage	1.9e-48	100.0
WP_000391814.1\|29322_29616_+	hypothetical protein	A0A1S5SCP4	Streptococcus_phage	3.1e-37	100.0
WP_001289768.1\|29608_30448_+	DnaD domain protein	A0A1S5SCN0	Streptococcus_phage	3.1e-130	88.9
WP_000228218.1\|30587_31358_+	ATP-binding protein	A0A1S5SD21	Streptococcus_phage	5.2e-140	100.0
WP_000470303.1\|31372_31567_+	hypothetical protein	A0A1S5SCY7	Streptococcus_phage	1.8e-28	100.0
WP_000891969.1\|31566_31794_+	hypothetical protein	A0A1S5SCL8	Streptococcus_phage	2.3e-40	100.0
WP_001105096.1\|31978_32170_+	hypothetical protein	A0A1S5SCV3	Streptococcus_phage	1.4e-25	100.0
WP_000875947.1\|32159_32492_+	hypothetical protein	A0A1S5SCI4	Streptococcus_phage	6.0e-61	100.0
WP_000516820.1\|32531_32996_+	hypothetical protein	A0A1S5SCN9	Streptococcus_phage	4.9e-85	100.0
WP_001028147.1\|33104_33647_+\|integrase	site-specific integrase	A0A1S5SCL7	Streptococcus_phage	9.8e-101	100.0
WP_000143215.1\|34076_34394_+	HNH endonuclease	A0A1S5SD32	Streptococcus_phage	1.5e-56	100.0
WP_000601030.1\|34530_35016_+	hypothetical protein	A0A1S5SCZ6	Streptococcus_phage	5.0e-80	99.4
WP_075275080.1\|35341_36721_+\|terminase	terminase	A0A1S5SCM6	Streptococcus_phage	2.1e-272	99.8
WP_075275078.1\|36873_37872_+\|portal	phage portal protein	A0A1S5SCP3	Streptococcus_phage	1.8e-188	99.7
WP_000413203.1\|37918_38461_+\|head,protease	HK97 family phage prohead protease	A0A1S5SCT6	Streptococcus_phage	1.2e-98	100.0
WP_000855224.1\|38475_39729_+\|capsid	phage capsid protein	A0A1S5SCZ2	Streptococcus_phage	4.4e-229	100.0
WP_000154006.1\|39754_40090_+	hypothetical protein	A0A1S5SCM7	Streptococcus_phage	4.1e-57	100.0
WP_000842790.1\|40086_40392_+\|head,tail	head-tail adaptor protein	A0A1S5SCR5	Streptococcus_phage	9.5e-37	100.0
WP_001074487.1\|40391_40739_+	hypothetical protein	A0A1S5SCP8	Streptococcus_phage	3.5e-59	100.0
WP_000534621.1\|40725_41070_+	hypothetical protein	A0A1S5SCM8	Streptococcus_phage	1.2e-59	100.0
WP_000221469.1\|41083_41752_+	hypothetical protein	A0A1S5SD39	Streptococcus_phage	7.0e-125	100.0
WP_000591561.1\|41753_42230_+	hypothetical protein	A0A1S5SD04	Streptococcus_phage	7.8e-86	100.0
WP_000852167.1\|42416_45155_+\|tail	phage tail tape measure protein	A0A1S5SD82	Streptococcus_phage	0.0e+00	100.0
WP_000161553.1\|45151_45874_+\|tail	phage tail protein	A0A1S5SCW9	Streptococcus_phage	2.8e-135	100.0
WP_012291606.1\|45874_54991_+	peptidase S74	A0A1S5SCJ9	Streptococcus_phage	0.0e+00	99.9
WP_001091107.1\|55084_55288_+	hypothetical protein	A0A1S5S819	Streptococcus_phage	3.8e-26	100.0
WP_000852249.1\|55290_55641_+	hypothetical protein	A0A060QMT7	Streptococcus_phage	4.7e-64	100.0
WP_001165344.1\|55650_56067_+\|holin	holin	A0A1S5SCE8	Streptococcus_phage	1.9e-67	100.0
WP_001186229.1\|56070_56403_+\|holin	phage holin	A0A1S5SCK0	Streptococcus_phage	7.4e-51	100.0
WP_000350504.1\|56406_57363_+	N-acetylmuramoyl-L-alanine amidase family protein	A0A1S5SCM9	Streptococcus_phage	3.0e-145	100.0
WP_001030863.1\|57822_57972_-	hypothetical protein	C5J952	Streptococcus_phage	9.1e-17	95.9
WP_000291870.1\|58252_58720_+	nucleoside deaminase	NA	NA	NA	NA
WP_000266837.1\|58928_60071_-\|integrase	site-specific integrase	U4KJ82	Streptococcus_phage	3.4e-212	99.7
WP_001020945.1\|60189_60540_-	hypothetical protein	Q9MBY8	Streptococcus_phage	7.3e-57	100.0
WP_000136430.1\|60553_60934_-	ImmA/IrrE family metallo-endopeptidase	A0A1S5SE39	Streptococcus_phage	4.2e-66	100.0
WP_000153672.1\|60955_61312_-	helix-turn-helix transcriptional regulator	A0A1S5SDR1	Streptococcus_phage	4.2e-60	100.0
WP_000638668.1\|61587_61773_+	helix-turn-helix transcriptional regulator	A0A1S5SDM7	Streptococcus_phage	1.0e-25	98.4
WP_001004041.1\|61774_62473_+	oxidoreductase	A0A1S5SDI0	Streptococcus_phage	7.6e-130	100.0
WP_000989840.1\|62658_63000_+	replication protein	A0A1S5SEB2	Streptococcus_phage	1.1e-49	100.0
WP_000450965.1\|63156_63423_+	hypothetical protein	A0A1C9LX40	Streptococcus_phage	1.1e-41	100.0
WP_001134280.1\|63506_63959_+	hypothetical protein	A0A1S5S8L8	Streptococcus_phage	3.2e-81	99.3
WP_000774580.1\|63964_64666_+	single-stranded DNA-binding protein	A0A1S5SEM6	Streptococcus_phage	1.5e-117	100.0
WP_000237813.1\|64668_65661_+	DUF1351 domain-containing protein	A0A141E1L4	Streptococcus_phage	1.6e-173	96.1
WP_001203350.1\|65682_65859_+	hypothetical protein	A0A1S5SEI1	Streptococcus_phage	2.8e-25	100.0
WP_000609580.1\|65848_66394_+	single-stranded DNA-binding protein	A0A141DZL2	Streptococcus_phage	3.3e-72	96.1
WP_000161128.1\|67594_67798_+	hypothetical protein	U4KJ79	Streptococcus_phage	4.4e-30	100.0
WP_000358622.1\|67851_68286_+	hypothetical protein	A0A1S5SG21	Streptococcus_phage	7.4e-67	100.0
WP_000206140.1\|68287_69025_+	hypothetical protein	A0A1S5S8J4	Streptococcus_phage	5.5e-131	99.2
WP_001286809.1\|69041_69254_+	hypothetical protein	A0A1S5SEA6	Streptococcus_phage	1.7e-32	100.0
WP_000667209.1\|69264_69666_+	hypothetical protein	U4KJA0	Streptococcus_phage	1.9e-72	100.0
WP_000573749.1\|69667_69874_+	hypothetical protein	A0A1C9LXW1	Streptococcus_phage	6.2e-32	100.0
WP_000391842.1\|69923_70238_+	hypothetical protein	A0A1S5SBL6	Streptococcus_phage	2.5e-56	97.1
WP_001021763.1\|70239_70740_+	DUF1642 domain-containing protein	A0A141E1K4	Streptococcus_phage	5.7e-95	100.0
WP_000194856.1\|70739_71033_+	hypothetical protein	A0A1S5SDK0	Streptococcus_phage	9.4e-50	100.0
WP_000162611.1\|71032_71425_+	hypothetical protein	A0A1S5SED1	Streptococcus_phage	7.1e-69	100.0
WP_000425573.1\|71490_72585_+	DUF4417 domain-containing protein	A0A1S5SEG1	Streptococcus_phage	1.1e-202	100.0
WP_000057535.1\|72565_73312_+	hypothetical protein	A0A1S5SDN7	Streptococcus_phage	2.9e-135	100.0
WP_001136856.1\|73515_73974_+	hypothetical protein	A0A1C9LX59	Streptococcus_phage	3.6e-72	98.7
WP_000143806.1\|73963_75274_+\|terminase	PBSX family phage terminase large subunit	U4KJA9	Streptococcus_phage	1.8e-257	100.0
WP_000051859.1\|75286_76855_+\|portal	phage portal protein	U4KJ98	Streptococcus_phage	7.8e-300	99.6
WP_000169861.1\|76841_77015_+	hypothetical protein	A0A1S5SEA5	Streptococcus_phage	1.3e-22	100.0
WP_000730219.1\|77057_78209_+\|capsid	phage capsid protein	A0A1S5S8K9	Streptococcus_phage	1.9e-218	100.0
WP_000896122.1\|78347_78911_+	scaffold protein	A0A1S5SEM4	Streptococcus_phage	9.9e-80	100.0
WP_001139819.1\|78928_79810_+	hypothetical protein	Q0R578	Streptococcus_phage	2.1e-161	99.7
WP_001240344.1\|79820_80054_+	hypothetical protein	A0A1S5SEE1	Streptococcus_phage	6.8e-35	100.0
WP_000221835.1\|80096_80489_+	hypothetical protein	A0A1S5SE16	Streptococcus_phage	2.6e-63	100.0
WP_000565932.1\|80478_80850_+\|capsid	phage capsid protein	A0A1S5SDX7	Streptococcus_phage	8.0e-54	100.0
WP_000020373.1\|80849_81194_+	hypothetical protein	A0A1S5SCD0	Streptococcus_phage	8.5e-58	100.0
WP_001208881.1\|81193_81601_+\|capsid	phage capsid protein	A0A1S5SEE3	Streptococcus_phage	3.2e-72	100.0
WP_000198232.1\|81597_82047_+	hypothetical protein	A0A1S5S8R8	Streptococcus_phage	6.4e-82	100.0
WP_000129842.1\|82111_82600_+	hypothetical protein	A0A1S5SEB3	Streptococcus_phage	2.2e-83	100.0
WP_033706953.1\|82618_83182_+	phage Gp15 protein	A0A141DZI3	Streptococcus_phage	9.2e-102	100.0
WP_000129368.1\|83174_86456_+	tape measure protein	A0A1C9LX70	Streptococcus_phage	0.0e+00	98.0
WP_000161551.1\|86452_87967_+	hypothetical protein	A0A1S5SE21	Streptococcus_phage	2.0e-300	100.0
WP_078136555.1\|93548_94910_+	hypothetical protein	A0A126GGH9	Streptococcus_phage	8.1e-245	100.0
WP_000159974.1\|94920_96969_+	hypothetical protein	A0A1S5S8L5	Streptococcus_phage	0.0e+00	100.0
WP_000922100.1\|97028_97292_+	hypothetical protein	A0A1S5SEN3	Streptococcus_phage	1.8e-39	100.0
WP_000687457.1\|97301_97718_+\|holin	holin	A0A1S5SEC7	Streptococcus_phage	4.9e-68	100.0
WP_001186242.1\|97721_98054_+\|holin	phage holin	A0A1S5SG48	Streptococcus_phage	5.7e-51	100.0
WP_000701992.1\|99295_99739_+	dUTP diphosphatase	Q2WG49	Clostridium_botulinum_D_phage	2.1e-29	47.3
WP_000691236.1\|99740_100256_+	histidine phosphatase family protein	NA	NA	NA	NA
WP_075213698.1\|100269_101631_+	DNA repair protein RadA	NA	NA	NA	NA
WP_001809263.1\|101703_102201_+	carbonic anhydrase	NA	NA	NA	NA
WP_000272773.1\|102221_103037_+\|protease	PrsW family intramembrane metalloprotease	NA	NA	NA	NA
WP_000010163.1\|103181_104150_+	ribose-phosphate diphosphokinase	A0A1V0SHF7	Hokovirus	4.0e-44	34.7
WP_000492734.1\|104691_104925_-	hypothetical protein	NA	NA	NA	NA
104284:104355	attR	NA	NA	NA	NA
WP_000233180.1\|104917_105034_-	hypothetical protein	NA	NA	NA	NA
WP_061364461.1\|105248_105599_-	ribose-phosphate pyrophosphokinase	NA	NA	NA	NA
WP_001842036.1\|105854_108488_+	DNA polymerase I	A0A218MKQ4	uncultured_virus	9.4e-56	31.5
WP_000076500.1\|108572_109010_+	CoA-binding protein	NA	NA	NA	NA
WP_000009179.1\|109419_110430_-	YeiH family putative sulfate export transporter	NA	NA	NA	NA
WP_000366376.1\|110578_111748_+	pyridoxal phosphate-dependent aminotransferase	NA	NA	NA	NA
WP_000616164.1\|111744_112515_+	DNA repair protein RecO	NA	NA	NA	NA
WP_000717456.1\|112511_113504_+	phosphate acyltransferase PlsX	NA	NA	NA	NA
WP_000136447.1\|113509_113743_+	acyl carrier protein	A0A2I7RIC8	Vibrio_phage	3.3e-05	40.6
WP_001093075.1\|114281_114512_+\|bacteriocin	bacteriocin-like peptide BlpU	NA	NA	NA	NA
WP_000343888.1\|115262_116156_+	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_000837726.1\|116698_116995_+\|bacteriocin	circular bacteriocin, circularin A/uberolysin family	NA	NA	NA	NA

DBSCAN-SWA_2

184339 : 210816

Planktothrix_phage(50.0%)

bacteriocin,tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_078136768.1\|184339_184633_+\|bacteriocin	lactococcin 972 family bacteriocin	NA	NA	NA	NA
WP_000723959.1\|184687_186796_+\|bacteriocin	bacteriocin-associated integral membrane family protein	NA	NA	NA	NA
WP_000571330.1\|186792_187434_+	ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	4.3e-23	34.8
WP_001038475.1\|187640_188447_+	transporter substrate-binding domain-containing protein	NA	NA	NA	NA
WP_000031925.1\|188463_189660_+	argininosuccinate synthase	NA	NA	NA	NA
WP_001107614.1\|189688_191080_+	argininosuccinate lyase	NA	NA	NA	NA
WP_001189286.1\|191368_191689_-	hypothetical protein	NA	NA	NA	NA
WP_000424430.1\|192446_192818_+\|bacteriocin	SPH_0218 family bacteriocin-like peptide	NA	NA	NA	NA
WP_012291603.1\|192825_193038_+	hypothetical protein	NA	NA	NA	NA
WP_012291594.1\|193842_194901_+	hypothetical protein	NA	NA	NA	NA
WP_012291592.1\|195215_196193_+	hypothetical protein	NA	NA	NA	NA
WP_000424474.1\|196664_197039_+\|bacteriocin	SPH_0224 family bacteriocin-like peptide	NA	NA	NA	NA
WP_000511668.1\|197045_197228_+	hypothetical protein	NA	NA	NA	NA
WP_000619757.1\|197246_198149_+	hypothetical protein	NA	NA	NA	NA
WP_000424404.1\|198204_198558_+	hypothetical protein	NA	NA	NA	NA
WP_000072918.1\|198554_199283_+	hypothetical protein	NA	NA	NA	NA
WP_000770319.1\|200418_200658_+	hypothetical protein	M1Q0Z8	Streptococcus_phage	4.2e-16	54.1
WP_001035347.1\|201208_203326_+	pneumococcal surface protein A	NA	NA	NA	NA
WP_001282980.1\|203725_204847_+\|tRNA	tRNA 2-thiouridine(34) synthase MnmA	NA	NA	NA	NA
WP_000193609.1\|204987_205443_+	NUDIX hydrolase	NA	NA	NA	NA
WP_000639152.1\|205452_207366_+\|tRNA	tRNA uridine-5-carboxymethylaminomethyl(34) synthesis enzyme MnmG	NA	NA	NA	NA
WP_000331980.1\|207744_209424_-	ribonuclease J	NA	NA	NA	NA
WP_000639579.1\|209425_209659_-	DNA-dependent RNA polymerase auxiliary subunit epsilon family protein	NA	NA	NA	NA
WP_000282479.1\|209938_210154_+	hypothetical protein	NA	NA	NA	NA
WP_000974047.1\|210476_210629_-\|bacteriocin	fratricide two-peptide bacteriocin subunit CibB	NA	NA	NA	NA
WP_000180803.1\|210630_210816_-\|bacteriocin	fratricide two-peptide bacteriocin subunit CibA	NA	NA	NA	NA

DBSCAN-SWA_3

254087 : 264848

Streptococcus_phage(75.0%)

integrase

attL 254066:254082|attR 266751:266767

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
254066:254082	attL	NA	NA	NA	NA
WP_000704664.1\|254087_255254_-\|integrase	site-specific integrase	A0A1X9I5Y5	Streptococcus_phage	3.7e-153	70.1
WP_001233766.1\|255338_256853_-	ATPase AAA	NA	NA	NA	NA
WP_001107589.1\|257013_257727_-	helix-turn-helix domain-containing protein	Q708R9	Streptococcus_phage	2.0e-16	51.9
WP_000424665.1\|258124_258751_+	Rha family transcriptional regulator	R9QNB1	Lactococcus_phage	2.1e-30	40.8
WP_000141100.1\|259122_259575_+	hypothetical protein	NA	NA	NA	NA
WP_000174331.1\|259571_259772_+	hypothetical protein	NA	NA	NA	NA
WP_001003774.1\|259773_259989_+	hypothetical protein	NA	NA	NA	NA
WP_000058832.1\|259985_260327_+	hypothetical protein	NA	NA	NA	NA
WP_000492137.1\|260319_260601_+	hypothetical protein	A0A1X9I5U9	Streptococcus_phage	7.9e-30	67.8
WP_000158192.1\|260735_261602_+	hypothetical protein	A0A1X9I6L2	Streptococcus_phage	8.2e-126	75.0
WP_000434361.1\|261654_263124_+	DNA primase	Q9AZI5	Lactococcus_phage	8.1e-65	35.2
WP_000865230.1\|263486_263654_+	hypothetical protein	NA	NA	NA	NA
WP_000173130.1\|263737_264268_+	hypothetical protein	A0A1X9I5U4	Streptococcus_phage	2.8e-36	48.7
WP_000811078.1\|264338_264848_+	hypothetical protein	A0A1X9I5V2	Streptococcus_phage	5.8e-47	53.9
266751:266767	attR	NA	NA	NA	NA

DBSCAN-SWA_4

357793 : 474406

101

Streptococcus_phage(15.0%)

integrase,transposase,holin,tRNA,protease

attL 355198:355230|attR 396949:396981

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
355198:355230	attL	NA	NA	NA	NA
WP_000660465.1\|357793_358501_+\|protease	CPBP family intramembrane metalloprotease	NA	NA	NA	NA
WP_000240981.1\|358745_359726_+	dihydropteroate synthase	NA	NA	NA	NA
WP_000658425.1\|359727_361050_+	bifunctional folylpolyglutamate synthase/dihydrofolate synthase	NA	NA	NA	NA
WP_000380924.1\|361030_361585_+	GTP cyclohydrolase I FolE	E7DN69	Pneumococcus_phage	3.7e-39	43.8
WP_000372534.1\|361627_362440_+	dihydroneopterin aldolase	NA	NA	NA	NA
WP_000886031.1\|362484_362802_-	DUF960 domain-containing protein	NA	NA	NA	NA
WP_001044624.1\|363157_363604_+	50S ribosomal protein L13	NA	NA	NA	NA
WP_000075973.1\|363623_364016_+	30S ribosomal protein S9	NA	NA	NA	NA
WP_000199095.1\|366174_366645_-	hypothetical protein	NA	NA	NA	NA
WP_000370602.1\|366641_367532_-	hypothetical protein	NA	NA	NA	NA
WP_029658590.1\|369501_369903_-\|integrase	tyrosine-type recombinase/integrase	NA	NA	NA	NA
WP_001106634.1\|370278_371487_-	ATP-binding protein	NA	NA	NA	NA
WP_000050748.1\|371891_372068_+	hypothetical protein	NA	NA	NA	NA
WP_000688744.1\|372468_374682_+	alpha-xylosidase	NA	NA	NA	NA
WP_000203063.1\|374903_375380_-	glutathione peroxidase	NA	NA	NA	NA
WP_001193722.1\|375602_378806_+	LPXTG-anchored hyaluronate lyase	NA	NA	NA	NA
WP_000167291.1\|379949_380579_-	bifunctional 4-hydroxy-2-oxoglutarate aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase	NA	NA	NA	NA
WP_000161480.1\|380588_381590_-	sugar kinase	NA	NA	NA	NA
WP_000684777.1\|381620_382262_-	RpiB/LacA/LacB family sugar-phosphate isomerase	NA	NA	NA	NA
WP_000185877.1\|382280_383096_-	gluconate 5-dehydrogenase	NA	NA	NA	NA
WP_000706826.1\|383367_383802_+	PTS sugar transporter subunit IIA	NA	NA	NA	NA
WP_000592922.1\|383813_385004_+	glucuronyl hydrolase	NA	NA	NA	NA
WP_000178620.1\|385014_385506_+	PTS system mannose/fructose/N-acetylgalactosamine-transporter subunit IIB	NA	NA	NA	NA
WP_000026610.1\|385520_386300_+	PTS mannose/fructose/sorbose/N-acetylgalactosamine transporter subunit IIC	NA	NA	NA	NA
WP_000148019.1\|386286_387105_+	PTS mannose/fructose/sorbose transporter family subunit IID	NA	NA	NA	NA
WP_000381734.1\|387104_387398_+	preprotein translocase subunit YajC	NA	NA	NA	NA
WP_000657099.1\|387419_389321_+	alginate lyase family protein	NA	NA	NA	NA
WP_000412453.1\|389380_390382_+	LacI family DNA-binding transcriptional regulator	NA	NA	NA	NA
WP_000838121.1\|390491_390827_-	hypothetical protein	NA	NA	NA	NA
WP_000711739.1\|390837_391080_-	hypothetical protein	NA	NA	NA	NA
WP_000712366.1\|391090_391633_-	DUF3278 domain-containing protein	NA	NA	NA	NA
WP_001082472.1\|391648_391843_-	helix-turn-helix transcriptional regulator	I3VYZ1	Thermoanaerobacterium_phage	9.4e-06	42.6
WP_000159404.1\|392010_392961_+	16S rRNA (cytosine(1402)-N(4))-methyltransferase RsmH	NA	NA	NA	NA
WP_000840840.1\|392972_393290_+	cell division protein FtsL	NA	NA	NA	NA
WP_000872301.1\|393293_395546_+	PASTA domain-containing protein	NA	NA	NA	NA
WP_000470792.1\|395547_396528_+	phospho-N-acetylmuramoyl-pentapeptide- transferase	NA	NA	NA	NA
WP_001063409.1\|397276_399382_+\|protease	ATP-dependent Clp protease ATP-binding subunit	H6X3M6	Enterobacteria_phage	7.6e-117	37.4
396949:396981	attR	NA	NA	NA	NA
WP_000032550.1\|399677_400160_-	S-ribosylhomocysteine lyase	NA	NA	NA	NA
WP_000743629.1\|400254_401739_-	DUF1846 domain-containing protein	NA	NA	NA	NA
WP_001156847.1\|401891_403499_+	alpha-glucosidase	NA	NA	NA	NA
WP_001022224.1\|403658_403832_+	hypothetical protein	NA	NA	NA	NA
WP_000091050.1\|404900_406346_+	LCP family protein	A0A1X9I5X1	Streptococcus_phage	4.4e-132	59.4
WP_000565355.1\|406347_407079_+	tyrosine protein phosphatase	NA	NA	NA	NA
WP_000664156.1\|407087_407780_+	capsular polysaccharide biosynthesis protein CpsC	A0A1X9I5E1	Streptococcus_phage	3.2e-64	58.5
WP_001142552.1\|407789_408479_+	tyrosine-protein kinase	A0A1X9I5D6	Streptococcus_phage	7.1e-72	63.3
WP_001291066.1\|408493_409855_+	sugar transferase	NA	NA	NA	NA
WP_001005725.1\|409860_410604_+	WecB/TagA/CpsF family glycosyltransferase	NA	NA	NA	NA
WP_001076780.1\|410600_411425_+\|holin	LPS cholinephosphotransferase	A0A1V0SD50	Indivirus	4.0e-05	38.2
WP_000458862.1\|411426_412305_+	glycosyltransferase family 2 protein	NA	NA	NA	NA
WP_000221686.1\|412305_413640_+	oligosaccharide repeat unit polymerase	NA	NA	NA	NA
WP_001085099.1\|413667_415092_+	hypothetical protein	NA	NA	NA	NA
WP_000723325.1\|415156_416245_+	UDP-N-acetylglucosamine 2-epimerase (non-hydrolyzing)	A0A1V0SAG5	Catovirus	1.6e-25	30.2
WP_000676130.1\|416407_417277_+	glucose-1-phosphate thymidylyltransferase RfbA	K7QKA7	Escherichia_phage	2.0e-100	63.2
WP_001282454.1\|417277_417871_+	dTDP-4-dehydrorhamnose 3,5-epimerase	H9NC63	Sphingomonas_phage	3.3e-09	32.3
WP_000141495.1\|417882_418932_+	dTDP-glucose 4,6-dehydratase	I7HTA3	Enterobacteria_phage	3.7e-72	45.4
WP_000600902.1\|418997_419849_+	dTDP-4-dehydrorhamnose reductase	A0A291LA50	Escherichia_phage	1.5e-26	35.4
WP_000927991.1\|419924_420359_+\|transposase	transposase	A0A218MNE7	uncultured_virus	2.1e-05	24.6
WP_024478039.1\|420431_420737_+\|transposase	transposase	NA	NA	NA	NA
WP_001818890.1\|420666_420879_+\|transposase	transposase	NA	NA	NA	NA
WP_001809483.1\|420949_421108_+	hypothetical protein	NA	NA	NA	NA
WP_001155321.1\|421236_422190_-\|transposase	IS30-like element ISSpn8 family transposase	H7BWC8	unidentified_phage	1.6e-34	35.2
WP_000842600.1\|422551_424534_+	peptide ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_001032463.1\|424834_430138_+	YSIRK signal domain/LPXTG anchor domain surface protein	NA	NA	NA	NA
WP_001041860.1\|430304_432464_-	PBP1A family penicillin-binding protein	NA	NA	NA	NA
WP_000248779.1\|432460_433057_-	Holliday junction resolvase RecU	A0A1L2JY30	Aeribacillus_phage	5.1e-18	34.5
WP_000179542.1\|433123_433651_+	DUF1273 domain-containing protein	NA	NA	NA	NA
WP_000094897.1\|433720_434062_+	cell division regulator GpsB	NA	NA	NA	NA
WP_000711368.1\|434547_435705_+	class I SAM-dependent RNA methyltransferase	NA	NA	NA	NA
WP_000039263.1\|435717_437130_+	mid-cell-anchored protein MapZ	NA	NA	NA	NA
WP_000158800.1\|437205_438630_+	NADP-dependent phosphogluconate dehydrogenase	M4QQM4	Ostreococcus_lucimarinus_virus	2.7e-41	29.6
WP_000518011.1\|438641_439331_+	response regulator transcription factor	NA	NA	NA	NA
WP_000771049.1\|439429_440449_+\|holin	choline-binding protein CbpC	NA	NA	NA	NA
WP_000765667.1\|440566_441799_-	MFS transporter	NA	NA	NA	NA
WP_000196978.1\|443328_443658_+\|transposase	transposase	NA	NA	NA	NA
WP_000163315.1\|443779_444658_+	mevalonate kinase	NA	NA	NA	NA
WP_000373457.1\|444639_445593_+	diphosphomevalonate decarboxylase	NA	NA	NA	NA
WP_000562441.1\|445579_446587_+	phosphomevalonate kinase	NA	NA	NA	NA
WP_000210617.1\|446570_447581_+	type 2 isopentenyl-diphosphate Delta-isomerase	NA	NA	NA	NA
WP_001224639.1\|447657_448356_+	cell wall-active antibiotics response protein	NA	NA	NA	NA
WP_000743661.1\|448352_449348_+	sensor histidine kinase	NA	NA	NA	NA
WP_000698432.1\|449361_449994_+	response regulator transcription factor	NA	NA	NA	NA
WP_001820556.1\|449994_450237_+	DNA alkylation repair enzyme	NA	NA	NA	NA
WP_075218746.1\|450161_450473_+	DNA alkylation repair protein	NA	NA	NA	NA
WP_000754502.1\|450913_451153_+	hypothetical protein	NA	NA	NA	NA
WP_000771077.1\|452081_453104_+\|holin	choline-binding protein CbpF	NA	NA	NA	NA
WP_000134375.1\|453233_454067_-\|transposase	IS3 family transposase	A0A1B1P773	Bacillus_phage	8.6e-56	48.5
WP_000391668.1\|454713_456483_+	PTS mannitol transporter subunit IICBA	NA	NA	NA	NA
WP_000927679.1\|456506_458462_+	transcription antiterminator	NA	NA	NA	NA
WP_000764149.1\|458463_458901_+	PTS sugar transporter subunit IIA	NA	NA	NA	NA
WP_000682965.1\|458962_460099_+	mannitol-1-phosphate 5-dehydrogenase	NA	NA	NA	NA
WP_000116474.1\|460859_462143_+	trigger factor	NA	NA	NA	NA
WP_000454484.1\|462190_464557_-	ATP-dependent RecD-like DNA helicase	A0A0K2FLP8	Brevibacillus_phage	6.9e-58	27.2
WP_001048155.1\|464790_465405_-	signal peptidase I	NA	NA	NA	NA
WP_000146861.1\|465416_466289_-	ribonuclease HIII	NA	NA	NA	NA
WP_000002019.1\|466375_466678_+	cell division protein ZapA	NA	NA	NA	NA
WP_000622945.1\|466674_467223_+	CvpA family protein	NA	NA	NA	NA
WP_001035029.1\|467326_469663_+	endonuclease MutS2	Q94M10	Lactobacillus_phage	1.8e-21	50.0
WP_000891492.1\|470009_471332_+	sodium:alanine symporter family protein	NA	NA	NA	NA
WP_000206761.1\|471549_472098_+	carboxymuconolactone decarboxylase family protein	NA	NA	NA	NA
WP_000735971.1\|472207_473107_+	TDT family transporter	NA	NA	NA	NA
WP_000884262.1\|473131_474406_-\|tRNA	serine--tRNA ligase	A0A1B1IVT2	uncultured_Mediterranean_phage	3.3e-91	48.7

DBSCAN-SWA_5

547686 : 595086

Klosneuvirus(20.0%)

bacteriocin,protease,tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000181388.1\|547686_548190_+\|tRNA	tRNA (cytidine(34)-2'-O)-methyltransferase	NA	NA	NA	NA
WP_000185826.1\|548642_549206_+	ECF transporter S component	NA	NA	NA	NA
WP_001842683.1\|549195_549846_+	phosphatase PAP2 family protein	NA	NA	NA	NA
WP_000867296.1\|549872_550262_+	hypothetical protein	NA	NA	NA	NA
WP_000333653.1\|550266_550716_+	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_000418402.1\|550843_551431_+	DNA-directed RNA polymerase subunit delta	NA	NA	NA	NA
WP_000105240.1\|551820_553428_+	CTP synthase	A0A1J0FA14	Only_Syngen_Nebraska_virus	1.5e-141	47.0
WP_000026645.1\|553968_555600_-	Na/Pi cotransporter family protein	NA	NA	NA	NA
WP_000795198.1\|555892_560806_+	YSIRK-type signal peptide-containing protein	NA	NA	NA	NA
WP_001096743.1\|560895_562092_+	phosphoglycerate kinase	NA	NA	NA	NA
WP_000119888.1\|562227_562755_+	aromatic acid exporter family protein	NA	NA	NA	NA
WP_000659547.1\|562831_563188_+	MerR family transcriptional regulator	NA	NA	NA	NA
WP_001122900.1\|563224_564571_+	type I glutamate--ammonia ligase	NA	NA	NA	NA
WP_001808898.1\|564660_564780_-	hypothetical protein	NA	NA	NA	NA
WP_000410533.1\|564744_564894_+	hypothetical protein	NA	NA	NA	NA
WP_001220759.1\|565345_566626_+	restriction endonuclease subunit S	A0A1V0SKS6	Klosneuvirus	6.9e-12	29.2
WP_000651177.1\|566682_567480_+	tyrosine-type DNA invertase PsrA	A0A0H4TI16	Erysipelothrix_phage	1.3e-21	28.7
WP_012291636.1\|567490_568096_+	restriction endonuclease subunit S	NA	NA	NA	NA
WP_000187242.1\|568043_569612_-	restriction endonuclease subunit S	A0A1V0SLK8	Klosneuvirus	1.0e-12	25.6
WP_000029056.1\|569611_571075_-	SAM-dependent DNA methyltransferase	NA	NA	NA	NA
WP_000229096.1\|571087_573421_-	DEAD/DEAH box helicase family protein	Q5YA94	Bacillus_phage	4.5e-25	27.9
WP_000550237.1\|574099_574537_+	DUF2812 domain-containing protein	NA	NA	NA	NA
WP_000255769.1\|574700_575735_+	heat-inducible transcriptional repressor HrcA	NA	NA	NA	NA
WP_000046031.1\|575761_576286_+	nucleotide exchange factor GrpE	NA	NA	NA	NA
WP_000034662.1\|576765_578589_+	molecular chaperone DnaK	A0A0N9QXN8	Chrysochromulina_ericina_virus	1.3e-133	47.2
WP_000114422.1\|578590_578947_+	hypothetical protein	NA	NA	NA	NA
WP_001066301.1\|579348_580485_+	molecular chaperone DnaJ	E3T4P7	Cafeteria_roenbergensis_virus	1.7e-22	31.0
WP_000777760.1\|580806_581094_-	hypothetical protein	NA	NA	NA	NA
WP_001278301.1\|581103_581514_-	HIT family protein	B5LJ12	Mycobacterium_phage	3.4e-05	31.6
WP_000889919.1\|581581_582313_+	ABC transporter ATP-binding protein	A0A2H4PQG7	Staphylococcus_phage	4.1e-25	28.6
WP_000653766.1\|582309_583359_+	multidrug ABC transporter permease	NA	NA	NA	NA
WP_000132572.1\|583526_583856_-	hypothetical protein	NA	NA	NA	NA
WP_000876676.1\|584131_584470_+	response regulator transcription factor	NA	NA	NA	NA
WP_001219147.1\|584474_585212_+	response regulator transcription factor	NA	NA	NA	NA
WP_001028044.1\|585225_586566_+	sensor histidine kinase	NA	NA	NA	NA
WP_000358817.1\|586607_586763_-	quorum-sensing system pheromone BlpC	NA	NA	NA	NA
WP_001069098.1\|586819_588181_-\|bacteriocin	bacteriocin secretion accessory protein	NA	NA	NA	NA
WP_000205158.1\|588191_590345_-	peptide cleavage/export ABC transporter BlpA	W8CYL7	Bacillus_phage	4.8e-42	27.9
WP_001093261.1\|590626_590824_+\|bacteriocin	bacteriocin-like peptide BlpI	NA	NA	NA	NA
WP_001093248.1\|591290_591560_+\|bacteriocin	bacteriocin-like peptide BlpJ	NA	NA	NA	NA
WP_000379967.1\|591628_591859_+\|bacteriocin	bacteriocin-like peptide BlpU	NA	NA	NA	NA
WP_000346298.1\|591861_591981_+	hypothetical protein	NA	NA	NA	NA
WP_000727118.1\|592277_592442_+	hypothetical protein	NA	NA	NA	NA
WP_000877378.1\|592924_593308_+	hypothetical protein	NA	NA	NA	NA
WP_000760541.1\|593359_594049_+\|protease	CPBP family intramembrane metalloprotease	NA	NA	NA	NA
WP_000276498.1\|594090_594324_+	hypothetical protein	NA	NA	NA	NA
WP_000394045.1\|594474_595086_+\|protease	CPBP family intramembrane metalloprotease	NA	NA	NA	NA

DBSCAN-SWA_6

959121 : 967283

Streptococcus_phage(87.5%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000728266.1\|959121_961017_+	MBL fold metallo-hydrolase	Q332B9	Clostridium_botulinum_C_phage	2.5e-10	23.3
WP_073176995.1\|961096_962227_+	glutamate 5-kinase	A0A1X9I5D0	Streptococcus_phage	8.5e-115	58.7
WP_000254677.1\|962236_963499_+	glutamate-5-semialdehyde dehydrogenase	A0A1X9I5D4	Streptococcus_phage	1.1e-139	64.5
WP_000689693.1\|963502_964300_+	pyrroline-5-carboxylate reductase	A0A1X9I6T5	Streptococcus_phage	4.2e-60	50.6
WP_000033396.1\|964519_965158_+	dTMP kinase	M1PSC7	Streptococcus_phage	1.1e-74	67.6
WP_000806714.1\|965154_966045_+	DNA polymerase III subunit delta'	M1NSC1	Streptococcus_phage	4.9e-73	51.7
WP_000358228.1\|966084_966402_+	DNA replication initiation control protein YabA	M1PFV3	Streptococcus_phage	2.9e-28	60.0
WP_001166873.1\|966404_967283_+	16S rRNA (cytidine(1402)-2'-O)-methyltransferase	M1PLC5	Streptococcus_phage	3.9e-115	75.7

DBSCAN-SWA_7

1287968 : 1342984

Streptococcus_phage(70.0%)

protease,integrase,transposase,holin

attL 1280714:1280735|attR 1337787:1337808

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
1280714:1280735	attL	NA	NA	NA	NA
WP_000811992.1\|1287968_1288772_+\|holin	phosphorylcholine transferase LicD	A0A1V0SD50	Indivirus	5.3e-10	27.1
WP_029658100.1\|1288778_1289582_+\|holin	phosphorylcholine transferase LicD	A0A1V0SD50	Indivirus	2.0e-09	32.5
WP_012291583.1\|1289856_1293033_-	carbamoyl-phosphate synthase large subunit	NA	NA	NA	NA
WP_000166701.1\|1293345_1294425_-	glutamine-hydrolyzing carbamoyl-phosphate synthase small subunit	R4TGJ8	Halovirus	6.3e-59	35.9
WP_001293845.1\|1294474_1295398_-	aspartate carbamoyltransferase catalytic subunit	M1HGA5	Paramecium_bursaria_Chlorella_virus	8.7e-25	31.7
WP_000850024.1\|1295416_1295938_-	bifunctional pyr operon transcriptional regulator/uracil phosphoribosyltransferase PyrR	NA	NA	NA	NA
WP_000244451.1\|1296148_1296778_-	endonuclease III	NA	NA	NA	NA
WP_000773226.1\|1296777_1297320_-	DUF177 domain-containing protein	NA	NA	NA	NA
WP_000389597.1\|1297489_1297807_+	hypothetical protein	NA	NA	NA	NA
WP_001812708.1\|1298045_1299605_+	ABC-F family ATP-binding cassette domain-containing protein	A0A1B0RXA0	Streptococcus_phage	9.3e-11	27.5
WP_000895736.1\|1299753_1300653_-\|protease	zinc metalloprotease HtpX	NA	NA	NA	NA
WP_000219823.1\|1300654_1301215_-	LemA family protein	NA	NA	NA	NA
WP_000801941.1\|1301308_1302022_+	16S rRNA (guanine(527)-N(7))-methyltransferase RsmG	NA	NA	NA	NA
WP_001291561.1\|1302208_1303426_-\|integrase	tyrosine-type recombinase/integrase	A0A1S5SEW7	Streptococcus_phage	3.7e-233	100.0
WP_000814511.1\|1303507_1303711_-	excisionase	A0A1S5SF07	Streptococcus_phage	4.0e-31	100.0
WP_000857133.1\|1304171_1304402_-	helix-turn-helix domain-containing protein	A0A1S5SEX1	Streptococcus_phage	2.7e-36	100.0
WP_000804885.1\|1304398_1304821_-	sigma-70 family RNA polymerase sigma factor	A0A1S5SEW0	Streptococcus_phage	2.5e-72	100.0
WP_001227347.1\|1305325_1305679_+	helix-turn-helix transcriptional regulator	A0A1S5SFA6	Streptococcus_phage	1.3e-58	100.0
WP_000336323.1\|1305738_1305906_-	conjugal transfer protein	D0R0F6	Streptococcus_phage	1.6e-14	68.0
WP_000691747.1\|1306024_1307944_-	tetracycline resistance ribosomal protection protein Tet(M)	A0A1S5SF82	Streptococcus_phage	0.0e+00	96.6
WP_001814923.1\|1307959_1308076_-	tetracycline resistance determinant leader peptide	NA	NA	NA	NA
WP_001224320.1\|1308320_1309256_-	conjugal transfer protein	A0A1S5SF22	Streptococcus_phage	7.7e-170	99.0
WP_000769864.1\|1309252_1310254_-	peptidase P60	A0A1S5SEZ8	Streptococcus_phage	6.5e-191	99.7
WP_012291584.1\|1310250_1312428_-	membrane protein	A0A1S5SF30	Streptococcus_phage	0.0e+00	99.9
WP_000331161.1\|1312430_1314878_-	ATP-binding protein	A0A1S5SF64	Streptococcus_phage	0.0e+00	99.9
WP_000506270.1\|1314861_1315368_-	conjugal transfer protein	A0A1S5SEX7	Streptococcus_phage	8.6e-91	100.0
WP_000342539.1\|1315342_1315840_-	antirestriction protein ArdA	A0A1S5SF25	Streptococcus_phage	1.7e-91	100.0
WP_001009056.1\|1315956_1316178_-	hypothetical protein	A0A1S5SEY0	Streptococcus_phage	4.3e-31	100.0
WP_000019067.1\|1316357_1317605_+\|transposase	ISL3 family transposase	Q6V7R1	Burkholderia_virus	3.9e-12	23.9
WP_001038795.1\|1317861_1318599_-	23S rRNA (adenine(2058)-N(6))-methyltransferase Erm(B)	E4ZFQ0	Streptococcus_phage	3.1e-134	99.2
WP_001814874.1\|1318723_1318807_-	23S rRNA methyltransferase attenuation leader peptide	NA	NA	NA	NA
WP_029658041.1\|1318855_1319065_-	peptide-binding protein	A0A1X9I6D5	Streptococcus_phage	1.5e-12	78.7
WP_012291622.1\|1319045_1320275_-	XRE family transcriptional regulator	A0A1S5SEX3	Streptococcus_phage	2.4e-232	99.8
WP_000879507.1\|1320297_1320450_-	hypothetical protein	NA	NA	NA	NA
WP_000813488.1\|1320452_1321838_-	DNA translocase FtsK	A0A1S5SFB5	Streptococcus_phage	1.1e-265	100.0
WP_000985015.1\|1321866_1322253_-	YdcP family protein	A0A1S5SF96	Streptococcus_phage	3.0e-64	100.0
WP_000420682.1\|1322268_1322583_-	YdcP family protein	A0A1S5SF38	Streptococcus_phage	5.2e-54	100.0
WP_012291612.1\|1323214_1324498_+	uracil transporter	Q9KX94	Enterobacteria_phage	1.5e-59	35.5
WP_000863651.1\|1324593_1326165_-	signal recognition particle protein	NA	NA	NA	NA
WP_000402071.1\|1326176_1326509_-	putative DNA-binding protein	NA	NA	NA	NA
WP_001246397.1\|1326599_1326965_-	DUF1934 domain-containing protein	NA	NA	NA	NA
WP_001003504.1\|1327048_1328353_+	HD domain-containing protein	E3T4P8	Cafeteria_roenbergensis_virus	1.7e-26	30.2
WP_000023498.1\|1328365_1329172_+	sugar-phosphatase	NA	NA	NA	NA
WP_001009001.1\|1329214_1330213_+	SAP domain-containing protein	NA	NA	NA	NA
WP_001068669.1\|1330492_1330840_-	50S ribosomal protein L19	NA	NA	NA	NA
WP_000237416.1\|1330958_1331288_-	fluoride efflux transporter CrcB	A0A2H4PQR0	Staphylococcus_phage	6.3e-10	37.8
WP_000712098.1\|1331281_1331656_-	fluoride efflux transporter CrcB	NA	NA	NA	NA
WP_000362435.1\|1331652_1331919_-	chorismate mutase	NA	NA	NA	NA
WP_001162129.1\|1332034_1332478_-	flavodoxin	NA	NA	NA	NA
WP_000401775.1\|1332581_1333517_+	bifunctional oligoribonuclease/PAP phosphatase NrnA	NA	NA	NA	NA
WP_001808393.1\|1333570_1333855_+	type B 50S ribosomal protein L31	NA	NA	NA	NA
WP_001835775.1\|1333911_1334400_-	hypothetical protein	NA	NA	NA	NA
WP_000199549.1\|1336232_1337579_+	NADP-specific glutamate dehydrogenase	NA	NA	NA	NA
WP_000711942.1\|1338074_1338245_-	hypothetical protein	NA	NA	NA	NA
1337787:1337808	attR	NA	NA	NA	NA
WP_000941986.1\|1340307_1340604_-	hypothetical protein	NA	NA	NA	NA
WP_000093668.1\|1340616_1340760_-	hypothetical protein	NA	NA	NA	NA
WP_000869754.1\|1340761_1341049_-	hypothetical protein	NA	NA	NA	NA
WP_088804224.1\|1341633_1342984_+\|transposase	IS3-like element ISSpn4 family transposase	A0A1B1P773	Bacillus_phage	1.8e-63	49.6

DBSCAN-SWA_8

1451975 : 1458983

Streptococcus_phage(42.86%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_025169196.1\|1451975_1452692_-	CapA family protein	A0A0N9SJ77	Staphylococcus_phage	1.0e-25	30.5
WP_001272961.1\|1453204_1453816_+	peptide deformylase	E3SLL2	Synechococcus_phage	4.9e-16	42.4
WP_000855753.1\|1453860_1454589_+	23S rRNA (guanosine(2251)-2'-O)-methyltransferase RlmB	NA	NA	NA	NA
WP_000272306.1\|1454627_1455539_-	thioredoxin-disulfide reductase	G3MA85	Bacillus_virus	4.5e-90	51.8
WP_000926599.1\|1455604_1455829_-	DUF4059 family protein	NA	NA	NA	NA
WP_000590970.1\|1455906_1456650_-	amino acid ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	4.7e-29	40.5
WP_001103449.1\|1456649_1457450_-	amino acid ABC transporter permease	NA	NA	NA	NA
WP_000889093.1\|1457607_1457964_-	arsenate reductase family protein	M1PLC0	Streptococcus_phage	1.2e-33	57.3
WP_001170346.1\|1457976_1458489_-	methylated-DNA--[protein]-cysteine S-methyltransferase	M1PFU9	Streptococcus_phage	1.3e-46	55.6
WP_000405859.1\|1458488_1458983_-	GNAT family N-acetyltransferase	M1PSC3	Streptococcus_phage	8.5e-43	52.8

DBSCAN-SWA_9

1548122 : 1554881

Streptococcus_phage(50.0%)

protease

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000081002.1\|1548122_1549091_+	NAD(P)/FAD-dependent oxidoreductase	Q9JRK7	Streptococcus_phage	1.8e-65	99.2
WP_000011303.1\|1549124_1550036_-	DNA-binding protein WhiA	Q7AWZ3	Streptococcus_phage	2.6e-154	99.3
WP_001231086.1\|1550032_1551010_-	YvcK family protein	A1IMD5	Streptococcus_phage	1.2e-184	100.0
WP_000163035.1\|1551006_1551897_-	RNase adapter RapZ	A0A0R8VB27	Thermobifida_phage	6.7e-06	29.8
WP_001140413.1\|1551948_1552329_-	RidA family protein	NA	NA	NA	NA
WP_000422606.1\|1552339_1552927_-	YihA family ribosome biogenesis GTP-binding protein	NA	NA	NA	NA
WP_012972566.1\|1552935_1554168_-\|protease	ATP-dependent Clp protease ATP-binding subunit ClpX	G3M9Z9	Bacillus_virus	2.9e-132	59.2
WP_000442260.1\|1554204_1554375_-	hypothetical protein	NA	NA	NA	NA
WP_000162471.1\|1554374_1554881_-	dihydrofolate reductase	A0A1B2IAU3	Erwinia_phage	3.0e-19	33.0

DBSCAN-SWA_10

1842890 : 1850222

uncultured_Mediterranean_phage(33.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000167845.1\|1842890_1843592_+	UDP-glucose 4-epimerase	A0A2K9L1R4	Tupanvirus	1.7e-33	35.1
WP_000777246.1\|1844014_1844974_+	ABC transporter permease	A0A2H4IY97	uncultured_Caudovirales_phage	4.0e-57	40.8
WP_001193668.1\|1844963_1845920_+	iron chelate uptake ABC transporter family permease subunit	NA	NA	NA	NA
WP_000764306.1\|1845916_1846669_+	ABC transporter ATP-binding protein	W6JKT0	Anomala_cuprea_entomopoxvirus	5.6e-14	27.9
WP_000858260.1\|1846764_1847730_+	siderophore ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_000821640.1\|1847954_1848197_-	membrane protein insertion efficiency factor YidD	A0A2H4PQM5	Staphylococcus_phage	1.3e-17	59.4
WP_001222228.1\|1848196_1848919_-	rRNA pseudouridine synthase	NA	NA	NA	NA
WP_000105310.1\|1848905_1849475_-	segregation/condensation protein B	A0A1B1IVT7	uncultured_Mediterranean_phage	5.0e-15	34.9
WP_000351907.1\|1849493_1850222_-	segregation/condensation protein A	A0A1B1IVW1	uncultured_Mediterranean_phage	5.3e-09	22.3

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage