CRISPRimmunity

Please click to download your results

Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NC_010331	Francisella philomiragia subsp. philomiragia ATCC 25017 plasmid pFPHI01, complete sequence	0 crisprs	NA	0	0	0	0
NC_010336	Francisella philomiragia subsp. philomiragia ATCC 25017, complete sequence	2 crisprs	csa3,cas3,DEDDh,cas4,cas1,cas2	1	4	6	0

Results visualization

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Crispr_ID: NC_010336_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_010336_1

24627-24724

Orphan

Consensus_repeat	Method
TTCCAATTACCAATCGGTTGATT	CRISPRCasFinder

1 spacers

The CRISPR arrays of NC_010336_1

>merge|NC_010336|1|24627-24724|CRISPRCasFinder
TTCCAATTACCAATCGGTTGATTAAAACTTCTAGCTCTATAAAACATATGATCCATGTTTTCTACCTTTGAGGTGTTCCAATTACCAATTGGTTGATT

>NC_010336|1|1|24627-24724|CRISPRCasFinder
TTCCAATTACCAATCGGTTGATT	AAAACTTCTAGCTCTATAAAACATATGATCCATGTTTTCTACCTTTGAGGTG
TTCCAATTACCAATTGGTTGATT

Protein	Signature genes	Signature genes Name	Protein_function
NC_010336.1\|WP_012279600.1\|35943_36975_-\|SIS-domain-containing-protein	unknown	unknown	gnl\|CDD\|225132
NC_010336.1\|WP_012279587.1\|21492_22335_+\|CBS-domain-containing-protein	unknown	unknown	gnl\|CDD\|226910
NC_010336.1\|WP_080513602.1\|31956_32769_-\|family-20-glycosylhydrolase	unknown	unknown	gnl\|CDD\|119337
NC_010336.1\|WP_012279582.1\|17279_17873_-\|thymidine-kinase	unknown	unknown	gnl\|CDD\|235272
NC_010336.1\|WP_012279580.1\|14572_15442_+\|ribosome-biogenesis-GTPase-YlqF	unknown	unknown	gnl\|CDD\|274669
NC_010336.1\|WP_012279592.1\|26223_27276_-\|DNA/RNA-non-specific-endonuclease	unknown	unknown	gnl\|CDD\|214889
NC_010336.1\|WP_012279588.1\|22334_23831_+\|apolipoprotein-N-acyltransferase	unknown	unknown	gnl\|CDD\|234721
NC_010336.1\|WP_012279589.1\|23851_24352_+\|hypothetical-protein	unknown	unknown	unknown
NC_010336.1\|WP_012279598.1\|32774_34397_-\|family-20-glycosylhydrolase	unknown	unknown	gnl\|CDD\|119337
NC_010336.1\|WP_012279583.1\|17875_18520_-\|O-methyltransferase	unknown	unknown	gnl\|CDD\|226607
NC_010336.1\|WP_012279594.1\|29175_29883_-\|peptidoglycan-editing-factor-PgeF	unknown	unknown	gnl\|CDD\|376831
NC_010336.1\|WP_012279586.1\|21014_21491_+\|rRNA-maturation-RNase-YbeY	unknown	unknown	gnl\|CDD\|234575
NC_010336.1\|WP_012279585.1\|20038_21022_+\|PhoH-family-protein	unknown	unknown	gnl\|CDD\|224616
NC_010336.1\|WP_012279599.1\|34513_35890_-\|sugar-porter-family-MFS-transporter	unknown	unknown	gnl\|CDD\|340917
NC_010336.1\|WP_012279596.1\|31200_31947_+\|Nif3-like-dinuclear-metal-center-hexameric-protein	unknown	unknown	gnl\|CDD\|182741
NC_010336.1\|WP_041268060.1\|27361_29179_-\|aminopeptidase-P-family-protein	unknown	unknown	gnl\|CDD\|238518
NC_010336.1\|WP_012279584.1\|18706_20035_+\|tRNA-(N6-isopentenyl-adenosine(37)-C2)-methylthiotransferase-MiaB	unknown	unknown	gnl\|CDD\|237673
NC_010336.1\|WP_012279595.1\|29897_31103_-\|flavodoxin-dependent-(E)-4-hydroxy-3-methylbut-2-enyl-diphosphate-synthase	unknown	unknown	gnl\|CDD\|234737
NC_010336.1\|WP_012279581.1\|15510_17250_+\|sel1-repeat-family-protein	unknown	unknown	gnl\|CDD\|276807
NC_010336.1\|WP_012279591.1\|25363_26233_+\|class-A-beta-lactamase	unknown	unknown	gnl\|CDD\|379138

Protein	Function_ID	Function_description	E-value
NC_010336.1\|WP_012279600.1\|35943_36975_-\|SIS-domain-containing-protein	gnl\|CDD\|225132	COG2222, AgaS, Predicted phosphosugar isomerases [Cell envelope biogenesis, outer membrane].	7.92522e-93
NC_010336.1\|WP_012279587.1\|21492_22335_+\|CBS-domain-containing-protein	gnl\|CDD\|226910	COG4535, CorC, Putative Mg2+ and Co2+ transporter CorC [Inorganic ion transport and metabolism].	3.03096e-86
NC_010336.1\|WP_080513602.1\|31956_32769_-\|family-20-glycosylhydrolase	gnl\|CDD\|119337	cd06569, GH20_Sm-chitobiase-like, The chitobiase of Serratia marcescens is a beta-N-1,4-acetylhexosaminidase with a glycosyl hydrolase family 20 (GH20) domain that hydrolyzes the beta-1,4-glycosidic linkages in oligomers derived from chitin. Chitin is degraded by a two step process: i) a chitinase hydrolyzes the chitin to oligosaccharides and disaccharides such as di-N-acetyl-D-glucosamine and chitobiose, ii) chitobiase then further degrades these oligomers into monomers. The GH20 hexosaminidases are thought to act via a catalytic mechanism in which the catalytic nucleophile is not provided by solvent or the enzyme, but by the substrate itself.	3.80907e-33
NC_010336.1\|WP_012279582.1\|17279_17873_-\|thymidine-kinase	gnl\|CDD\|235272	PRK04296, PRK04296, thymidine kinase; Provisional.	1.7813e-92
NC_010336.1\|WP_012279580.1\|14572_15442_+\|ribosome-biogenesis-GTPase-YlqF	gnl\|CDD\|274669	TIGR03596, GTPase_YlqF, ribosome biogenesis GTP-binding protein YlqF. Members of this protein family are GTP-binding proteins involved in ribosome biogenesis, including the essential YlqF protein of Bacillus subtilis, which is an essential protein. They are related to Era, EngA, and other GTPases of ribosome biogenesis, but are circularly permuted. This family is not universal, and is not present in Escherichia coli, and so is not as well studied as some other GTPases. This model is built for bacterial members. [Protein synthesis, Other].	1.08671e-107
NC_010336.1\|WP_012279592.1\|26223_27276_-\|DNA/RNA-non-specific-endonuclease	gnl\|CDD\|214889	smart00892, Endonuclease_NS, DNA/RNA non-specific endonuclease. A family of bacterial and eukaryotic endonucleases share the following characteristics: they act on both DNA and RNA, cleave double-stranded and single-stranded nucleic acids and require a divalent ion such as magnesium for their activity. An histidine has been shown to be essential for the activity of the Serratia marcescens nuclease. This residue is located in a conserved region which also contains an aspartic acid residue that could be implicated in the binding of the divalent ion.	2.09522e-53
NC_010336.1\|WP_012279588.1\|22334_23831_+\|apolipoprotein-N-acyltransferase	gnl\|CDD\|234721	PRK00302, lnt, apolipoprotein N-acyltransferase; Reviewed.	2.00496e-117
NC_010336.1\|WP_012279598.1\|32774_34397_-\|family-20-glycosylhydrolase	gnl\|CDD\|119337	cd06569, GH20_Sm-chitobiase-like, The chitobiase of Serratia marcescens is a beta-N-1,4-acetylhexosaminidase with a glycosyl hydrolase family 20 (GH20) domain that hydrolyzes the beta-1,4-glycosidic linkages in oligomers derived from chitin. Chitin is degraded by a two step process: i) a chitinase hydrolyzes the chitin to oligosaccharides and disaccharides such as di-N-acetyl-D-glucosamine and chitobiose, ii) chitobiase then further degrades these oligomers into monomers. The GH20 hexosaminidases are thought to act via a catalytic mechanism in which the catalytic nucleophile is not provided by solvent or the enzyme, but by the substrate itself.	7.1169e-44
NC_010336.1\|WP_012279583.1\|17875_18520_-\|O-methyltransferase	gnl\|CDD\|226607	COG4122, COG4122, Predicted O-methyltransferase [General function prediction only].	1.01513e-32
NC_010336.1\|WP_012279594.1\|29175_29883_-\|peptidoglycan-editing-factor-PgeF	gnl\|CDD\|376831	pfam02578, Cu-oxidase_4, Multi-copper polyphenol oxidoreductase laccase. Laccases are multi-copper oxidoreductases able to oxidize a wide variety of phenolic and non-phenolic compounds and are widely distributed among both prokaryotes and eukaryotes. There are two main active catalytic sites with conserved histidines that are capable of binding four copper atoms.	4.83814e-75
NC_010336.1\|WP_012279586.1\|21014_21491_+\|rRNA-maturation-RNase-YbeY	gnl\|CDD\|234575	PRK00016, PRK00016, metal-binding heat shock protein; Provisional.	1.46033e-49
NC_010336.1\|WP_012279585.1\|20038_21022_+\|PhoH-family-protein	gnl\|CDD\|224616	COG1702, PhoH, Phosphate starvation-inducible protein PhoH, predicted ATPase [Signal transduction mechanisms].	6.45892e-134
NC_010336.1\|WP_012279599.1\|34513_35890_-\|sugar-porter-family-MFS-transporter	gnl\|CDD\|340917	cd17359, MFS_XylE_like, D-xylose-proton symporter and similar transporters of the Major Facilitator Superfamily. This subfamily includes bacterial transporters such as D-xylose-proton symporter (XylE or XylT), arabinose-proton symporter (AraE), galactose-proton symporter (GalP), major myo-inositol transporter IolT, glucose transport protein, putative metabolite transport proteins YfiG, YncC, and YwtG, and similar proteins. The symporters XylE, AraE, and GalP facilitate the uptake of D-xylose, arabinose, and galactose, respectively, across the boundary membrane with the concomitant transport of protons into the cell. IolT is involved in polyol metabolism and myo-inositol degradation into acetyl-CoA. The XylE-like subfamily belongs to the Glucose transporter -like (GLUT-like) family of the Major Facilitator Superfamily (MFS) of membrane transport proteins. MFS proteins are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	2.538e-74
NC_010336.1\|WP_012279596.1\|31200_31947_+\|Nif3-like-dinuclear-metal-center-hexameric-protein	gnl\|CDD\|182741	PRK10799, PRK10799, type 2 GTP cyclohydrolase I.	5.7764e-90
NC_010336.1\|WP_041268060.1\|27361_29179_-\|aminopeptidase-P-family-protein	gnl\|CDD\|238518	cd01085, APP, X-Prolyl Aminopeptidase 2. E.C. 3.4.11.9. Also known as X-Pro aminopeptidase, proline aminopeptidase, aminopeptidase P, and aminoacylproline aminopeptidase. Catalyses release of any N-terminal amino acid, including proline, that is linked with proline, even from a dipeptide or tripeptide.	3.11157e-108
NC_010336.1\|WP_012279584.1\|18706_20035_+\|tRNA-(N6-isopentenyl-adenosine(37)-C2)-methylthiotransferase-MiaB	gnl\|CDD\|237673	PRK14325, PRK14325, (dimethylallyl)adenosine tRNA methylthiotransferase; Provisional.	0
NC_010336.1\|WP_012279595.1\|29897_31103_-\|flavodoxin-dependent-(E)-4-hydroxy-3-methylbut-2-enyl-diphosphate-synthase	gnl\|CDD\|234737	PRK00366, ispG, flavodoxin-dependent (E)-4-hydroxy-3-methylbut-2-enyl-diphosphate synthase.	0
NC_010336.1\|WP_012279581.1\|15510_17250_+\|sel1-repeat-family-protein	gnl\|CDD\|276807	sd00010, SLR, Sel1-like repeat. Sel1-like repeats (SLRs) share similar alpha-helical conformations with Tetratricopeptide repeats (TPRs), but with different consensus sequence lengths and superhelical topologies. SLRs contain 36 to 44 amino acids and are present in bacteria and eukaryotes but not in archaea. SLR proteins are involved in a variety of functions, and many serve as adaptor proteins for the assembly of macromolecular complexes. The SLR family was named after the Caenorhabditis elegans Sel1 protein which is predicted to fold into 11 SLRs, a transmembrane domain, and an N-terminal signal sequence. The human Sel1L protein contains an additional fibronectin type-II domain and an N-terminal PEST sequence. Its downregulation is associated with the development of breast and pancreatic carcinomas.	1.42714e-15
NC_010336.1\|WP_012279591.1\|25363_26233_+\|class-A-beta-lactamase	gnl\|CDD\|379138	pfam13354, Beta-lactamase2, Beta-lactamase enzyme family. This family is closely related to Beta-lactamase, pfam00144, the serine beta-lactamase-like superfamily, which contains the distantly related pfam00905 and PF00768 D-alanyl-D-alanine carboxypeptidase.	3.21338e-37

>NC_010336.1|WP_012279589.1|23851_24352_+|hypothetical-protein
MKNKIFLVSIFGLALSYSFASEIYEKDDNGVPTFSNEPTKNSKKLDLGDINVVDEPSYSDKITINNNINISNQTNSSSNDNNQLENNYYSGYCSQYYDNYSSYSYIPYECGYFFHRPYYGLDNAANRTWDNIDREKTDHYIQQNINANRITQAAAPMGMRMAGGRR
>NC_010336.1|WP_012279588.1|22334_23831_+|apolipoprotein-N-acyltransferase
MKKIILKITPPIVSGALLTLAFAPFRIDVLAIVALVAFFYLLNRSVRIRDAFFTSTLFGIGFFGTSISWVYISIHLFTESVAAGLSAAIALVILLSFLHIIPFGVFSHILTRKANNFSKLLIYPALWTLFEIVKANLLWGGFPWVSLGYSQTESPLIWYANIGGVYLVSYIIALIASLIVFFICDNTSTKKTISVVAIIVALYLGGYIIKYNQPETQTNQPQKVVLIQGDFVQGFKWDRDNFAKMQKYYQQAASKYKDSLIILSENAIPNYRQFMSEYFKNLTKLANKNNNAMLIGSLSADQSTAGTKIYNSSIIIGKGEGVYNKHHLVPFGEYFPIKFFGYVDSVGLSSFNAGDNIQPIMTAFGSPIANFICYEVAYPEQVRDQLQGARLISIISDDSWFGDSIAREQQLQISQVRAIENSKYVLTTTSNGITAVINPDGVIVKELPKDTRASLEQTVYLNDYHSIWMKIGMALIFGLIILSLVIGIILKELTKKES
>NC_010336.1|WP_012279587.1|21492_22335_+|CBS-domain-containing-protein
MAENNHFIKKLTSSIFNIKSENALIDAINRAADNEVIDKTSQNMLIGAMKISSLDVGDIMISHTKIVAIDMSMSISEILKKTINSSHTRLPVYCRDKSEVLGILHSKDLLKLIFEKEIESSDDEELKAEDIKTILRPAIFIPETKKLNAMLKDFKNSQNHIAIVVDEYGAISGLITIEDVLEEIVGDIEDEFDISSQNIIKIADDKFIIDATTSIEDFNEYFATSIDDDGDYDTIAGMIIQTLERLPEKGDSIVIDGLKFIVQEADNRKIIKILVEKFKK
>NC_010336.1|WP_012279586.1|21014_21491_+|rRNA-maturation-RNase-YbeY
MDSLNLNVINDDEHPIPNQDLLEKCFALVADKHNISQAEVNVSIVSNQEIQQINKQFRHKDKPTNIISFEFEKPEGLPEDIAANFWGDIVIAPEVLKKEAKEQNKNLDDHWQHIFIHGLLHLLGYDHIDDIEAEEMENLEIELLAELGIANPYIEQEN
>NC_010336.1|WP_012279585.1|20038_21022_+|PhoH-family-protein
MNKTQFVLEPYNYDAMMLLCGNLDENIRAIENYFDVEIKHRADEFEITSESSANNTQSKRFIKSCYAEILAGNTELDLEQITTILNATAKEKVASSNKAQKKVEEAEVQLRSKKLKARTQNQAIYLDNIKNNFVTFGVGPAGTGKTYMAIACAVSAYERGEVRRIVLVRPAVEAGEKLGFLPGDLAQKIDPYLRPMYDALFDFMGVEKVTKLIEKQAIEIAPLAYMRGRTINDSFIVLDESQNTTKEQMKMFLTRIGFNTTAVITGDITQVDLPKNVTSGLRHALSILDNIDGVAISYLKSVDIVRHQIVQKIVNAYDKHEENTKNG
>NC_010336.1|WP_012279584.1|18706_20035_+|tRNA-(N6-isopentenyl-adenosine(37)-C2)-methylthiotransferase-MiaB
MKEQKKVFIKTLGCQMNEYDSQKMHEVLDEHFHTVKTDDYKEADIILINTCSIREKAQEKVFHELGRWKNLKKKKEDLVIGVGGCVASQEGENIIKRAPFVDLVFGPQTIHRLPEMIKRKQSTQESQVDISFPEVEKFDFLPEPKAEGAKAYVSIMEGCDKYCSYCVVPYTRGPEVNRPFEDVLGECAALAEQGVKEITLLGQNVNHYLGPMENGETADLALLIHFIAEIDGIERIRFTTSHPVEFSQNLIDAYGSVPELANHLHLPVQHGSDRVLINMKRNHTILEFKQKIRKLRAIRPDITISSDFIVGFPGETEEDFQKLMDLVKDVNFDQSFSFIYSKRPGTPAADLPDDTPMEVKKDRLKRLQDLLNSNAQIISRQMVGTEQRILVEGTSKKDDNVLAGRTENNRIVNFIGDKSLIGQFAMVKITESLPNSLRGELI
>NC_010336.1|WP_012279583.1|17875_18520_-|O-methyltransferase
MKQNQFTEDSIWQYCIKHTSDLSANLNLLNNSTKEFVHGAQMLSEKIVAKLLQFFVFTTQAKICVDVGTFTGMSAIAMAEVSVNTKVYTIDRANQSGEAIAREFIAKYPNIEYCQGNAIDILPTLPNHIDIAFIDADKKQTQQYFDILIEKLSDKGVIIVDDILWRGEVIDPQDKRAKALDDFNKYVNQRDDLETLVLPIRHGINIIRKKYKGF
>NC_010336.1|WP_012279582.1|17279_17873_-|thymidine-kinase
MAKLYFRYSAMDAGKTLDLLKVAYNYEDRGKKPLVLTSAIDKRAGLNKVKSRIGIDQDAYSLTDQDNIFEFVKNYNQKHKVDCVLIDEIHFFTQAQVWQLSDIADQLDIPVICYGLRTNYLGQPFETAALLLAIADTLEEVKTICHCGKKASFNMMVQNGKAIKEGNPIVVDDDSLKDIDTRYVSVCRKHWKKGEYQ
>NC_010336.1|WP_012279581.1|15510_17250_+|sel1-repeat-family-protein
MSELENTPTKPKKIGHIKATRKNILSALLIVAVISSGVYGINSYLDYKHNKFLKEYNAAITDIKNHNSNGYNNAFSILKEIVGDNEATAQDFFYLGYSYQYGFGTEKNYFDAYKYYKKSASLNYPQAFYQIGVLYEDGLGVNKDNTKAMDYFKKSYDLGYKNSIVDLENMISSNNNLISTTDPEILYEIYLAYKDGKLPNENDKTIDKYIITAAANGYEPAIIVQARNFTDKGDNYRALMLWQTLLYSSDPKVAELAKKETVEVENLVKQERLRTLEKERLKRIEIQQNLRKKQLDDTRRIEQVQKKIEFALSTPKQEITNLDGLIYLNLSRVNKGQLQQFYSDILKASIDIKLLNTDNNLDYSYIDDFLILSKYIDIRSSLRFDFGEKANNNKYEGIVYLFYNYENKMVKQSAIAALKNIKAKESSLTPKLANAQEQPLDYSNKPIKEKVKQTEKSKTNVDKVQLTYEEKIQRMQVFAQKGDFRQLYKLEQAAKDGDVYAMYYAGEYYYNVKEYKTALDYFNEAADKGYGPAYYKLASLYYNEEQNGVPYDKEKAMYYYKKAAQLGVRNAQHILMLIE
>NC_010336.1|WP_012279580.1|14572_15442_+|ribosome-biogenesis-GTPase-YlqF
MLHWFPGHMHKATKEFRKKMPFTDIAIEIVDARIPDSSSNHVLEDIVGDKPIIRILSKSDLADPQITKQWLDFYKGSAIAVNTLQDKNIVKKILELAQKKCPSRGTVLKPTRAIIFGLPNVGKSTMINKLAGRKVAKTGNEPAVTKLQQRIDISKNFMIFDTPGIMFPSPKSEVSGYRIASIGSIRDTAMDYEGTAYYLIDLLKQKNTKKFLSRYNFISEQDFLEKHPQEIIKDISATKTNYNVKQAAKNIVHDFRAGHFGKISLEDPQIIQQEKEQFIMNQLEQEDNL
>NC_010336.1|WP_012279591.1|25363_26233_+|class-A-beta-lactamase
MKRLLFASLSLIPTILLANTTLDDSFKNLEDKYHGKLGIYTVNTDDKTNISYNQNYHFPICSVFKFLLVGAVLEYDMQHEGFLDKKILITQDDIGTLGYAPVTGKNIGKTLTISQLNYAAILSDNPAANILVREIGGLEKLNKLVAKLGDKDTIIKNDEPKINYTKPDSNINKTTPKAITQDIYNLAFGNILDKKHREIFIGYLQKNNTGANRIAYSMPKNWIIGDKTGTCGEYAATNDVAIIWPQNKPPFALSILYTNPSDVKAPSNEKIIQQASKLTANSLLNNGYK
>NC_010336.1|WP_012279592.1|26223_27276_-|DNA/RNA-non-specific-endonuclease
MAAKNKNSNKDNKKSISYVKIILFLVLTISGGFSGLLFDKFDIKEKFIDLRYKIYNYFTSEPLKHYTAKDNQNIIAKFFSESDSAKDQQQQINQFENLKQYPPVRTLPAVTDYCHGFLAYGNPSYDVTEGLGQSNLYLCRDGYVVGYNYQTKEASWVAFKLTKSKVANKLKRDDKFKEDSDVPFVYRATLDDYSRSGYDRGHLASYASMDFSKKSADESFLLSNMSPQKAGLNRQGWERLETDERIWANMYDSIYVYTGPIYKKQKIYKTIGDNKIAVPDYFFKIIYVPSKNQAIAFVMPNARVEKTKIANYRVSIKDIEQRTGLHFLTNIQDRDSVINNVSSMWRTAYL
>NC_010336.1|WP_041268060.1|27361_29179_-|aminopeptidase-P-family-protein
MNLNISNGDKMSEKLQVLRRLMKEKGYDFYLVPSIDDHNNEYVPECWQYRSWISGFDGSAGDVLIGLDKSYLSTDGRYFTQAEYQLDKNEFVLLKQTAFSSKIEEWLEENLAGKTLAIDPKKIGITRAENLLSIAKKVDGKIVFDNTNLVAQAQKELNQETAIPKENIFVHEIQYAGQSVDSKLRNLRTYLKSIKAECLIETSLDSIMWTLNIRGRDIKNTPLAICYMVVTVESTFLYIDKDKVTDEIHSHFEQNNVIVLDYKEFFADLKKFAAKFVIDSNVASYAVKLAIKENEHSKLIEDTSPIILSKALKNSIEINGSKDAHKKDAAAFISWWHWMENNYQGIDELDAMEKLREFRAKQKGYVEDSFSYIVGHAANGAIIHYSAKRDANLKKIDDQAPLLCDSGGQYKEGTTDITRVLHFGRPSNEHRRYYTLVLKGHLGLGRAVFPKGTTGSHLDVLAREHLWHFCSDYAHGTGHGVGSFLGVHEGPQRINSASKVELMPGMILSNEPGAYFPGQFGIRIENLCYVKQRNQDSPTGHGPFYCFEDLTLVPYEYKLIETWMLTYTEKKTINNYYSRIRKEVLPLIEDQEVKDFLLFKTRHIK
>NC_010336.1|WP_012279594.1|29175_29883_-|peptidoglycan-editing-factor-PgeF
MSVVFVNTPFARLKLGYTNNTQGFSKDKYAKFNLADNVGDKHLAVEKNRNSFRSYINADIKWLRQNHTNIVTSFDEYNGDFCDAIVTDKPKQACVILTADCLPIILFDKKMTKVAAIHAGWRGLLQGILEQTLKEFVGLDLVAWFGPCISGNFYEVGRDVHDKFVEQHDAYGQAFRSKSEDKYLFDMKMVARQILNDNHCFDIVDSGLCTYSNKRFYSYRKEGITGRQATFVWFE
>NC_010336.1|WP_012279595.1|29897_31103_-|flavodoxin-dependent-(E)-4-hydroxy-3-methylbut-2-enyl-diphosphate-synthase
MSKTNVVRVGDVLIGGNNPVVVQSMTDTYTADIEKTVKQILALHKAGSEIVRITVNDEPAAAAVPEIVKELAKHDCHVPLVGDFHYNGHTLLSKYPECAKALAKYRINPGNVGFGKKKDTQFAEIIKIAIANDKPVRIGVNWGSLDQALLARLIDENNLQENPLTLQQIMHKALITSALESAKYAQDLGLAKDKIIISCKVSEVQDLVAVYQKLAKECDYALHLGLTEAGMGTKGIVASAVSLGILLQQGIGNTIRVSLTPAPNASRTEEVRVCREILQNLGMRTFTPSVTSCPGCGRTTSSFFRELTSTVKDHLDEKMHTWKDQYHGVEAMKVAVMGCVVNGPGESKNADIGISLPGSGESPVAPVFIDGKKAHTLRGDNISKEFIEIVENYVKNRYAKK
>NC_010336.1|WP_012279596.1|31200_31947_+|Nif3-like-dinuclear-metal-center-hexameric-protein
MNFKELENYLNNYFDIAQFKDYCPNGLQIQGDRDIKKVVTGVTACQALIDQAVKENADAIIVHHGYFWKGESYPIVGIKYERISKLIKNGIHLFGYHLPLDGHSKIGNNILLAKKLNLTNLEFFETGSKPDISVIGNCDLDLDSFSNLIENELDKKPIVISTKQQNKKVAICTGGAQDYIEYAYQAGADTFISGEISERTTHAARELGINYIAAGHHATEKEGVKAIADLLKQEFTLDAKFIDIDNPA
>NC_010336.1|WP_080513602.1|31956_32769_-|family-20-glycosylhydrolase
MYKLFDNQNTVYFEPQISVGGDEVSADAWTNDSTCENQKDLNALEKSHNFFKELQQNTNLRISGWQQTVQNDPNGNLAGGIDKNSIPSEKTGYIWVWSAFNSSGYSEAQQLAKVGYSTVLAYADDIYFDLSYNPDFWEPGFYWATKYADTHAALNSALDSKTTITSLSTKDAKNIKGLEGAMWSENINNANHLWYMAFPKMIGLAEASWADPNITVKDKKINWNSLVYRLGTDNTNFLGYIDRIINPSNDKKIISYRGYPEGVSQELPRK
>NC_010336.1|WP_012279598.1|32774_34397_-|family-20-glycosylhydrolase
MKKNLIAILLGSQCLLSSGFATDFDVQKIQIKNISQNNRKFDMSIDVKINQNQSGDWLFGFYMPRTYNSSKDVNPNLTLKVTDLSTKKSANLSYVKKADNLTTMPIYGDGYSNLFRATTDFELEEGHIYRFSFENNNLWVPANISSLPQSFFLIDSNGNVVTSNANLDAYISKNTKEISSIQGYDSAKINIEIQKKLQSYVDNSIASDSSEFANQYHLIPTPLSISNVGSKQNINSDNGVYVDDSNSKQNIKLLNQYFKTDKITTNDLKAVTDKSHASIIFEKDLSIKNKEGYILKIIDNKIYIRYQTNAGLFYAIQTLRNLYQKDNVGSKNTSNMLILPQVTIKDQPRFEYRGILLDVARHYFSVQTIKTLIDAMVSQKLNTLHIHFSDDEGFRLALDSVDVKKASTRGYNDSSTIPTQMYQQANLDKSNYFNQKIKDSDIISPNYPTAATIYEGYYSKKDIQEIISYANARQITVIPEIDLPGHAKALIDSAPDIFINKSDKSDYISVQGYYDDVLPVCLYNRQILKEKSLQLRLIRL
>NC_010336.1|WP_012279599.1|34513_35890_-|sugar-porter-family-MFS-transporter
MKEANKLKVFMIIFFSAMGGMLYGYDIGIIGGALPFIKSELGMTAAQESFLGGSVLFGGAFAILIGGILADIFGRKNMITASGLIFTISVFMIYFAESYDFLLFSRLVQGVAVGFISITVPLYLTESVPSMIRGLAVTCFQLFLTAGILISVAVSLLFISNDPVTGLETGDWRNMFLTALIPGLFVFIGGFLLIKSPRWLIMKNREQEAEKILSETIGVDAAKQQMQEVKALIEKTKNEGSLLSSLTKRHYLMPMLIVFSVAILAQMTGINSILQYAPTMLKETGLGSVYAAVVGGVAITGLNFVTTIIAVVIADKIERKFVITFGTLMVSIVLLTLAILMYAMPDTSAKGMVLLIGFILYIFFFAIGPGAYIWVIMSELLPTNIRSKGLAVALFLNSMASAILASSVMPVTQHFNGNYGVILGICGVCTLVYSFIAFKFVPKTNGRTLEEIEQGFIK
>NC_010336.1|WP_012279600.1|35943_36975_-|SIS-domain-containing-protein
MTKTLMHQEASSSFEKVANQLKLNKDIVKTIVKTLKEKNIKRVITVARGSSDCVANYAKYLFETQLGFSVSSLPPSITTIYNKNIGDENTLAIGISQSGGSPDLRLALEGCKKAGCTTLAIVNVEKSPLADSADLVLPVRADAENAVAATKSVITSLVALVNIVAEYNQDQALLDSLNNLPKALEKSLNSDWTPAIEELKKSKNMFVIGRGFGFPIVQEMALKFKETCGIHAEAFSSAEVLHGPFALMNQTFTTFTILQHDESAQGTREIVKRMTDLGVRTVFATTDNQSDAKVHLHIDVKTHPILETVVILQKFYLMVNELALSLGYNPDSPSNLKKVTETV

You can click texts colored in the table to view more detailed information

Click the colored protein region to show detailed information

Crispr_ID: NC_010336_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_010336_2

1788023-1788379

Unclear

V-A

Consensus_repeat	Method
GTCTAAGAACTTTAAATAATTTCTACTGTTGTAGAT	PILER-CR
GTCTAAGAACTTTAAATAATTTCTACTGTTGTAGAT	CRISPRCasFinder
GTCTAAGAACTTTAAATAATTTCTACTGTTGTAGATN	CRT

5 spacers

cas2,cas1,cas4

The CRISPR arrays of NC_010336_2

>merge|NC_010336|2|1788023-1788379|PILER-CR,CRISPRCasFinder,CRT
GTCTAAGAACTTTAAATAATTTCTACTGTTGTAGATCTCATTTAGAAATTCAATTTTTAAATTCTGTCTAAGAACTTTAAATAATTTCTACTGTTGTAGATAACCCTAAAGATTCTAACGGTGTTATTGTCTAAGAACTTTAAATAATTTCTACTGTTGTAGATGAAATGGTGGAGTAATGCCAAGCAACGGTCTAAGAACTTTAAATAATTTCTACTGTTGTAGATGGACTATTCTTTTAATGTTTGATACATAGTCTAAGAACTTTAAATAATTTCTACTGTTGTAGATACTTGATACTATATGTACGAACATTTAGAAGTCTAAAAACATTAAAAAATTCTGTTAATGTAGGTT

>NC_010336|2|1|1788023-1788313|PILER-CR
GTCTAAGAACTTTAAATAATTTCTACTGTTGTAGAT	CTCATTTAGAAATTCAATTTTTAAATTCT
GTCTAAGAACTTTAAATAATTTCTACTGTTGTAGAT	AACCCTAAAGATTCTAACGGTGTTATT
GTCTAAGAACTTTAAATAATTTCTACTGTTGTAGAT	GAAATGGTGGAGTAATGCCAAGCAACG
GTCTAAGAACTTTAAATAATTTCTACTGTTGTAGAT	GGACTATTCTTTTAATGTTTGATACATA
GTCTAAGAACTTTAAATAATTTCTACTGTTGTAGAT

>NC_010336|2|2|1788023-1788313|CRISPRCasFinder
GTCTAAGAACTTTAAATAATTTCTACTGTTGTAGAT	CTCATTTAGAAATTCAATTTTTAAATTCT
GTCTAAGAACTTTAAATAATTTCTACTGTTGTAGAT	AACCCTAAAGATTCTAACGGTGTTATT
GTCTAAGAACTTTAAATAATTTCTACTGTTGTAGAT	GAAATGGTGGAGTAATGCCAAGCAACG
GTCTAAGAACTTTAAATAATTTCTACTGTTGTAGAT	GGACTATTCTTTTAATGTTTGATACATA
GTCTAAGAACTTTAAATAATTTCTACTGTTGTAGAT

>NC_010336|2|1|1788023-1788379|CRT
GTCTAAGAACTTTAAATAATTTCTACTGTTGTAGAT	CTCATTTAGAAATTCAATTTTTAAATTCT
GTCTAAGAACTTTAAATAATTTCTACTGTTGTAGAT	AACCCTAAAGATTCTAACGGTGTTATT
GTCTAAGAACTTTAAATAATTTCTACTGTTGTAGAT	GAAATGGTGGAGTAATGCCAAGCAACG
GTCTAAGAACTTTAAATAATTTCTACTGTTGTAGAT	GGACTATTCTTTTAATGTTTGATACATA
GTCTAAGAACTTTAAATAATTTCTACTGTTGTAGAT	ACTTGATACTATATGTACGAACATTTAGAA
GTCTAAAAACATTAAAAAATTCTGTTAATGTAGGTT

Protein	Signature genes	Signature genes Name	Protein_function
NC_010336.1\|WP_012280953.1\|1788466_1789267_-\|alpha/beta-hydrolase	unknown	unknown	gnl\|CDD\|177659
NC_010336.1\|WP_012280945.1\|1778286_1779357_+\|dipeptide-epimerase	unknown	unknown	gnl\|CDD\|239435
NC_010336.1\|WP_012280958.1\|1792824_1793274_+\|acyl-CoA-thioesterase	unknown	unknown	gnl\|CDD\|223894
NC_010336.1\|WP_004287654.1\|1776227_1776569_+\|chorismate-mutase	unknown	unknown	gnl\|CDD\|214841
NC_010336.1\|WP_012280946.1\|1779372_1780020_+\|alpha/beta-fold-hydrolase	unknown	unknown	gnl\|CDD\|309968
NC_010336.1\|WP_012280957.1\|1792576_1792828_+\|glutaredoxin	unknown	unknown	gnl\|CDD\|239510
NC_010336.1\|WP_012280954.1\|1789276_1789852_-\|outer-membrane-lipoprotein-carrier-protein-LolA	unknown	unknown	gnl\|CDD\|319983
NC_010336.1\|WP_080513614.1\|1786085_1786622_+\|type-V-CRISPR-associated-protein-Cas4	cas4	cd09637_cas4_CAS-I:CAS-II:CAS-V	gnl\|CDD\|213941
NC_010336.1\|WP_004287655.1\|1776604_1777075_+\|glutathione-peroxidase	unknown	unknown	gnl\|CDD\|238207
NC_010336.1\|WP_012280944.1\|1777123_1778290_+\|DUF819-family-protein	unknown	unknown	gnl\|CDD\|227792
NC_010336.1\|WP_012280961.1\|1794560_1796507_+\|BCCT-family-transporter	unknown	unknown	gnl\|CDD\|376718
NC_010336.1\|WP_012280952.1\|1787610_1787883_+\|CRISPR-associated-endonuclease-Cas2	cas2	pfam09827_cas2_CAS-I:CAS-II:CAS-III	gnl\|CDD\|378256
NC_010336.1\|WP_041268116.1\|1790263_1791346_+\|radical-SAM-protein	unknown	unknown	gnl\|CDD\|275338
NC_010336.1\|WP_041268115.1\|1780039_1780231_-\|hypothetical-protein	unknown	unknown	unknown
NC_010336.1\|WP_012280956.1\|1791382_1792498_-\|linear-amide-C-N-hydrolase	unknown	unknown	gnl\|CDD\|225591
NC_010336.1\|WP_012280959.1\|1793288_1793642_-\|hypothetical-protein	unknown	unknown	unknown
NC_010336.1\|WP_012280962.1\|1796499_1796979_-\|tryptophan-rich-sensory-protein	unknown	unknown	gnl\|CDD\|320706
NC_010336.1\|WP_012280960.1\|1793670_1794423_-\|RNA-methyltransferase	unknown	unknown	gnl\|CDD\|349968
NC_010336.1\|WP_003034639.1\|1786625_1787630_+\|type-V-CRISPR-associated-endonuclease-Cas1	cas1	cd09634_cas1_CAS-I:CAS-II:CAS-III:CAS-V	gnl\|CDD\|213942
NC_010336.1\|WP_012280947.1\|1780450_1781914_+\|bifunctional-ADP-dependent-NAD(P)H-hydrate-dehydratase/NAD(P)H-hydrate-epimerase	unknown	unknown	gnl\|CDD\|182554

Protein	Function_ID	Function_description	E-value
NC_010336.1\|WP_012280953.1\|1788466_1789267_-\|alpha/beta-hydrolase	gnl\|CDD\|177659	PLN00021, PLN00021, chlorophyllase.	1.09674e-06
NC_010336.1\|WP_012280945.1\|1778286_1779357_+\|dipeptide-epimerase	gnl\|CDD\|239435	cd03319, L-Ala-DL-Glu_epimerase, L-Ala-D/L-Glu epimerase catalyzes the epimerization of L-Ala-D/L-Glu and other dipeptides. The genomic context and the substrate specificity of characterized members of this family from E.coli and B.subtilis indicates a possible role in the metabolism of the murein peptide of peptidoglycan, of which L-Ala-D-Glu is a component. L-Ala-D/L-Glu epimerase is a member of the enolase-superfamily, which is characterized by the presence of an enolate anion intermediate which is generated by abstraction of the alpha-proton of the carboxylate substrate by an active site residue and is stabilized by coordination to the essential Mg2+ ion.	2.06243e-96
NC_010336.1\|WP_012280958.1\|1792824_1793274_+\|acyl-CoA-thioesterase	gnl\|CDD\|223894	COG0824, FcbC, Predicted thioesterase [General function prediction only].	9.91655e-24
NC_010336.1\|WP_004287654.1\|1776227_1776569_+\|chorismate-mutase	gnl\|CDD\|214841	smart00830, CM_2, Chorismate mutase type II. Chorismate mutase, catalyses the conversion of chorismate to prephenate in the pathway of tyrosine and phenylalanine biosynthesis. This enzyme is negatively regulated by tyrosine, tryptophan and phenylalanine..	2.35381e-05
NC_010336.1\|WP_012280946.1\|1779372_1780020_+\|alpha/beta-fold-hydrolase	gnl\|CDD\|309968	pfam05057, DUF676, Putative serine esterase (DUF676). This family of proteins are probably serine esterase type enzymes with an alpha/beta hydrolase fold.	1.79696e-09
NC_010336.1\|WP_012280957.1\|1792576_1792828_+\|glutaredoxin	gnl\|CDD\|239510	cd03418, GRX_GRXb_1_3_like, Glutaredoxin (GRX) family, GRX bacterial class 1 and 3 (b_1_3)-like subfamily; composed of bacterial GRXs, approximately 10 kDa in size, and proteins containing a GRX or GRX-like domain. GRX is a glutathione (GSH) dependent reductase, catalyzing the disulfide reduction of target proteins such as ribonucleotide reductase. It contains a redox active CXXC motif in a TRX fold and uses a similar dithiol mechanism employed by TRXs for intramolecular disulfide bond reduction of protein substrates. Unlike TRX, GRX has preference for mixed GSH disulfide substrates, in which it uses a monothiol mechanism where only the N-terminal cysteine is required. The flow of reducing equivalents in the GRX system goes from NADPH -> GSH reductase -> GSH -> GRX -> protein substrates. By altering the redox state of target proteins, GRX is involved in many cellular functions including DNA synthesis, signal transduction and the defense against oxidative stress. Different classes are known including E. coli GRX1 and GRX3, which are members of this subfamily.	4.67635e-12
NC_010336.1\|WP_012280954.1\|1789276_1789852_-\|outer-membrane-lipoprotein-carrier-protein-LolA	gnl\|CDD\|319983	cd16325, LolA, LolA, a periplasmic chaperone. This family contains periplasmic molecular chaperone LolA which binds to outer-membrane specific lipoproteins and transports them from inner membrane to outer membrane (OM) through LolB, a lipoprotein anchored to outer membranes. There are five Lol proteins (LolA, LolB, LolC, LolD, and LolE) involved in the sorting and membrane localization of lipoprotein and are highly conserved in Gram-negative bacteria. LolA accepts OM-specific lipoproteins that are released from the inner membrane by the LolCDE complex and transfers them to the OM receptor LolB. Studies have shown that hydrophobic surface patches large enough to accommodate acyl chains of the OM lipoproteins and the structural flexibility of LolA are important factors for its role as a periplasmic chaperone.	3.79959e-16
NC_010336.1\|WP_080513614.1\|1786085_1786622_+\|type-V-CRISPR-associated-protein-Cas4	gnl\|CDD\|213941	TIGR04328, hypothetical_protein_HMPREF9709_01098, CRISPR-associated protein Cas4, subtype PREFRAN. Members of this family are the Cas4 protein of a novel CRISPR subtype, PREFRAN, found in Prevotella bryantii B14, Prevotella disiens FB035-09AN, Francisella tularensis subsp. novicida, Francisella philomiragia, Butyrivibrio proteoclasticus B316, Helcococcus kunzii ATCC 51366, etc.	3.3904e-104
NC_010336.1\|WP_004287655.1\|1776604_1777075_+\|glutathione-peroxidase	gnl\|CDD\|238207	cd00340, GSH_Peroxidase, Glutathione (GSH) peroxidase family; tetrameric selenoenzymes that catalyze the reduction of a variety of hydroperoxides including lipid peroxidases, using GSH as a specific electron donor substrate. GSH peroxidase contains one selenocysteine residue per subunit, which is involved in catalysis. Different isoenzymes are known in mammals,which are involved in protection against reactive oxygen species, redox regulation of many metabolic processes, peroxinitrite scavenging, and modulation of inflammatory processes.	2.74178e-83
NC_010336.1\|WP_012280944.1\|1777123_1778290_+\|DUF819-family-protein	gnl\|CDD\|227792	COG5505, COG5505, Predicted integral membrane protein [Function unknown].	1.71915e-66
NC_010336.1\|WP_012280961.1\|1794560_1796507_+\|BCCT-family-transporter	gnl\|CDD\|376718	pfam02028, BCCT, BCCT, betaine/carnitine/choline family transporter.	0
NC_010336.1\|WP_012280952.1\|1787610_1787883_+\|CRISPR-associated-endonuclease-Cas2	gnl\|CDD\|378256	pfam09827, CRISPR_Cas2, CRISPR associated protein Cas2. Members of this family of bacterial proteins comprise various hypothetical proteins, as well as CRISPR (clustered regularly interspaced short palindromic repeats) associated proteins, conferring resistance to infection by certain bacteriophages.	5.95853e-13
NC_010336.1\|WP_041268116.1\|1790263_1791346_+\|radical-SAM-protein	gnl\|CDD\|275338	TIGR04545, rSAM_ahbD_hemeb, heme b synthase. Members of this family are AhbD (alternative heme biosynthetic protein D), a radical SAM enzyme in sulfate-reducing bacteria and methanogens that performs the last decarboxylations to synthesize heme b from Fe-coproporphyrin III. Members include DVU_0855, previously included in error in TIGR04055, the NirJ2 family thought to be involved in heme d1 biosynthesis. [Biosynthesis of cofactors, prosthetic groups, and carriers, Heme, porphyrin, and cobalamin].	6.26183e-143
NC_010336.1\|WP_012280956.1\|1791382_1792498_-\|linear-amide-C-N-hydrolase	gnl\|CDD\|225591	COG3049, COG3049, Penicillin V acylase and related amidases [Cell envelope biogenesis, outer membrane].	1.26324e-45
NC_010336.1\|WP_012280962.1\|1796499_1796979_-\|tryptophan-rich-sensory-protein	gnl\|CDD\|320706	cd15904, TSPO_MBR, Translocator protein (TSPO)/peripheral-type benzodiazepine receptor (MBR) family. This family contains tryptophan-rich translocator protein (TSPO), an integral membrane protein that is highly conserved from bacteria to mammals. In eukaryotes, it is mainly found in the outer mitochondrial membranes of steroid-synthesizing cells of the nervous system where it transports cholesterol into mitochondria. It is known to be highly expressed in metastatic cancer, steriodogenic tissues, as well as inflammatory and neurological diseases such as Alzheimer's and Parkinson's. TSPO is also known as the peripheral benzodiazepine receptor (MBR) and its ligands include benzodiazepine drugs, implicated in regulating apoptosis. In human, a single polymorphism A147T is associated with psychiatric disorders; the mutation causes structural changes in a region implicated in cholesterol binding. TSPO is homologous to bacterial tryptophan-rich sensory proteins, and their tryptophan residues are believed to be functionally important. In bacteria, TSPO acts as a negative regulator of expression of specific photosynthesis genes in response to oxygen/light; it catalyzes a photooxidative degradation of Proto porphyrine (PpIX). R. sphaeroides TSPO (RsTSPO) is involved in porphyrin transport, similar to human, while Arabidopsis translocator protein (AtTSPO) is regulated at multiple levels in response to salt stress and perturbations in tetrapyrrole metabolism.	4.11779e-42
NC_010336.1\|WP_012280960.1\|1793670_1794423_-\|RNA-methyltransferase	gnl\|CDD\|349968	cd18095, SpoU-like_rRNA-MTase, SAM-dependent rRNA methylase related to SpoU-TrmH. RNA 2'-O ribose methyltransferase catalyzes the methyltransfer from S-adenosyl-L-methionine (AdoMet) to the 2'-OH group of ribose in tRNA or rRNA. It is part of the SpoU family of MTases, a subfamily of the SPOUT methyltransferase superfamily. The SPOUT methyltransferase superfamily is a large class of S-adenosyl-L-methionine (AdoMet or SAM)-dependent RNA MTases which are structurally characterized by a deep trefoil knot.	1.32998e-49
NC_010336.1\|WP_003034639.1\|1786625_1787630_+\|type-V-CRISPR-associated-endonuclease-Cas1	gnl\|CDD\|213942	TIGR04329, hypothetical_protein_SbacW_07302_partial, CRISPR-associated endonuclease Cas1, subtype PREFRAN. Members of this family are the Cas1 endonuclease of a novel CRISPR subtype, PREFRAN, found in Prevotella bryantii B14, Prevotella disiens FB035-09AN, Francisella tularensis subsp. novicida, Francisella philomiragia, Butyrivibrio proteoclasticus B316, Helcococcus kunzii ATCC 51366, etc.	0
NC_010336.1\|WP_012280947.1\|1780450_1781914_+\|bifunctional-ADP-dependent-NAD(P)H-hydrate-dehydratase/NAD(P)H-hydrate-epimerase	gnl\|CDD\|182554	PRK10565, PRK10565, putative carbohydrate kinase; Provisional.	9.79074e-78

>NC_010336.1|WP_012280952.1|1787610_1787883_+|CRISPR-associated-endonuclease-Cas2
MLIVSYDFSNNKVRAKFAKFLESYGVRLQYSVFELKYSKRMLDLILAEIENHYVPLFTNADSVLIFNAPDKDVIKYGYAIHREQEVIFID
>NC_010336.1|WP_003034639.1|1786625_1787630_+|type-V-CRISPR-associated-endonuclease-Cas1
MFSKNDIESKNIVFVNIFDGVKLSLSLGNIVIKDKETDEVKTKLSVHKVLALFIVGNMTMTSQLLETCKKNAIQLVFMKNSFRPYLCFGDIAEANFLARYKQYSVVEQDISLARIFITSKIRNQHNLVKSLRDKTPEQQEIVKKNKQLIAELENTTSLAELMGIEGNVAKNFFKGFYGHLDSWQGRKPRIKQDPYNVVLDLGYSMLFNFVECFLRLFGFDLYKGFCHQTWYKRKSLVCDFVEPFRCIVDNQVRKSWNLGQFSVEDFGCKNEQFYIKKDKTKDYSKILFAEIISYKLEIFEYVREFYRAFMRDKEIAEYPIFCYETRRVYVDSQL
>NC_010336.1|WP_080513614.1|1786085_1786622_+|type-V-CRISPR-associated-protein-Cas4
MTWLNDFIFCPYSIYLHNIYSNASDATYYSSSQTKGRDAHKSIDKGIYSTKKDDLIGIDVINHKYGLVGKIDVFHKDKGLLVERKRQIKTIYDGYKYQLYAQYFCLQEMGYDVKAIKFYSMVDNKSYPIDIPTSAKLEKFEKHIQTIKQYNPMDNSFRQNIEKCKFCIYANLCDKTDL
>NC_010336.1|WP_012280947.1|1780450_1781914_+|bifunctional-ADP-dependent-NAD(P)H-hydrate-dehydratase/NAD(P)H-hydrate-epimerase
MQFLTEKQNREIEEYAISQGLNLIENASDEIVKLICNKFDKQSKILVIAGSGNNGSDGIAAAIKLFSLGYDVDVYRVFPKGNPDNQNYYQEFLKLKTPLDKLPDINNYDVVIDGIFGIGLDRDLQGDILELVKVINQNSKYTLAIDVPSGLGAFNAKVYGEAIQANETITFLADKQGLHTGDGLDYAGKVTVKELINSESIKLSQSEYQVYKKHIKDINLDNILRKRKNTNKGTYGNLAIIGGNVGMNGALQLAGKSSLYSGCGKVSMISLDKDFRADMSTPELMTKSLEDIPKNLNTFLALVVGVGFDTTDDSRQVLQLIIDNLTQSAIFDADALNIISTNQQIREKFIQLENKIITPHPAEAARLLGCTTKEVQDDRFVAVRALAKKYNSTVVLKGAGSLICKSDEIYINATGNQGMAVAGQGDVLSGIIGAFLAQDLDTLSASRLAVYVHGLAGDNIVKKLGGYVGIFPSRVAEEVCEVLNFLN
>NC_010336.1|WP_041268115.1|1780039_1780231_-|hypothetical-protein
MKKIAILIISLILFNLGFSIHTNDNKFFEATQFNNKNCRYAHEVGHNSFSEPEMNLACKPRSE
>NC_010336.1|WP_012280946.1|1779372_1780020_+|alpha/beta-fold-hydrolase
MSKDKVVILVHGFIKNSKDMSSLANFLKDGYDEVIAVDLPTTFVSVDVAVNKLCQIVKSIPSSKSLIFVAHSMGGIISCMTIDKLQLTNVEKCVFIASPFAGSRVADFGDRIPFYSRVLKPNKDLKVTDKYLEICNRVAEKVSVGLIAGNKYSKLNFLARLCLRNEHDGLVEVSSVFSINSLDRITLNKNHSQIHHDEETLTKVSFFLKTGRFLS
>NC_010336.1|WP_012280945.1|1778286_1779357_+|dipeptide-epimerase
MSKIIDIKTSIIKIPLKRTFITAVRSTNHIDSLAVELTLDNGVKGYGVAPATTAITGDTLQGMQYIIREIFAPVILGSDLSDYKQTLELAFKKVMFNSAAKMAIDLAYHDLLAKEQDISVAKLLGAKANSIVTDVSISCGNVAETIQNIQNGVEANFTAIKVKTGADFNRDIQLLKALDNEFSKNIKFRFDANQGWNLAQTKQFIEEINKYSLNVEIIEQPVKYYDIKAMAEITKFSNIPVVADESVFDAKDAERVIDEQACNMINIKLAKTGGILEAQKIKKLADSAGISCMVGCMMESPAGILATASFALAEDITVADLDPLDWVAKDLYSDYITFNEPNIILKDNLKGFGFNL
>NC_010336.1|WP_012280944.1|1777123_1778290_+|DUF819-family-protein
MISTSLSYISSLLLICSLIVLLSSKSKSKLFEYFPAIVIIYFVIVVLSAMGFWDSKSSEIIQTRLQLQDLILPVMLFLMLIRCDMRVVIKLGRKLLIAFFGATVSIIIAFVIMYLTVGKYISPDAWKGFSALSASWMGGTGNMIAVKQALSTPDNQMGYILLTDSISYSIWFAFLFALISRANIFDKWTKAGCIEEHISKVDINNPYDVKGDINFVGIFVLIAMAFTATDIAKILSSYLPATDLISAKTWTILLVTLFGFVGAMTPLAKIRSDSIIASIFLYFLVALIASGSSFKGFSQAPIYIVCGLMVLIIHAILMVIIAKIFRLNLAMCSIASLANIGGIAGAPILASAYTRSLVSIAVVMALLGFLIGTQGGLIVAKILSGFAI
>NC_010336.1|WP_004287655.1|1776604_1777075_+|glutathione-peroxidase
MSIYDFKLTKNDGSEYSLPNNKVLLIVNVASKCGFTKQYKGLQHLHKLYPDLEIVAFPCNSFGGQEPGSDEEIKSFCETNYDVTFPIMKKTKVNGKDAEPLFEYLKERAKGVLGTEAIKWNFTKFLVSKDGETVIRYAPKTIPEDLISDIENFLKD
>NC_010336.1|WP_004287654.1|1776227_1776569_+|chorismate-mutase
MKKYILILLSVATFSLSFAMSPSSFIAKPTSEKYESEIMDADEQIIKFIAKRQELRNQMLDLQKNQKLPSNDPFEDKDLAATRTNFAIQYNVSPKLVDQVFDILNSSAQKPAK
>NC_010336.1|WP_012280953.1|1788466_1789267_-|alpha/beta-hydrolase
MLKTKFFLSFVLFSIFAIVFTFSMSNAQDSKNSSKIIKETTNISLNIASSNYDIFYQKSNRNLPVVIVVHGFSRSKDNMSGWGSFLADHGYFVVVPNLPFWANHSKNAEFISELINYIYSNSDYKSIINNDLALVGFSAGGLATLIATSENTRVKLWIGLDPVDVGNLGSQAAKNINCPTYIIAASASACNTNNNYKNFITNLKENNLIKIDGAVHVDAEWPTSRFAELFCGRSTQQKRERFHDDVLTILDKSFKNESYIQNINKY
>NC_010336.1|WP_012280954.1|1789276_1789852_-|outer-membrane-lipoprotein-carrier-protein-LolA
MLKKVAIATSILVSGLVYAAPSADFAKVEEQLVKNDNYSGHFIQSRKIQGLDKPILASGEFELSKKDGLEWNQEKPFKSSLKATKDTITIKTADSPKSVFGEEDSPMVFSFTKIFLSVLEGDSKVIYDNFNTKFSGTTDNWTLVLTPKTELLSKALKEVTLKGGETITYVEVIDAQNNVMDIQFSDIEIDS
>NC_010336.1|WP_041268116.1|1790263_1791346_+|radical-SAM-protein
MKHQLKWMAWETTRRCNLKCVHCRSSSECEVVGHPDFSTEEGFRIIDNIVELANPVLVLSGGEPLLRADIFELAKYGANKGLRMALATNGSLVTDEICEKIKNSGISIVSLSIDGATAETHDDFRSQKGAFEATVNAAKLFKKHGIPFLINSSFTKRNQHEIKDVYKLAKSLEATAWYLFMIVPTGRGEELMQELIDVDDYQEILNWHYDMEADEQDMLVRPTCAPHYYRIRFERNKEDNAKVRSRALSFGTGGGKGCIAGQSICLLDVDGNVYPCSYLPVSAGNVKEKSFADIWQNSDVMHDMRDFSVYEGKCGSCEFIKICGGCRARAYNIHGSYLAEEPFCNHMPIKLKQSENNKNK
>NC_010336.1|WP_012280956.1|1791382_1792498_-|linear-amide-C-N-hydrolase
MCTNVFINKNQYKIEARSMDFPINIAFKNGWGYVGIENVTDVVIDADKIPESRIAKWTSKYGYFCRLGFESYVTDGLNTQGFSYSILYLDGTVYPSYDDNDNRPALAVYELGNFLLAMAKDVADALKLISEYQIVNSAVKLKDGIYMKNIPLHMCLRDANGNSAVIEFIGGKMYIHKNAGNVLTNAPTYEWHLSNIEEYKSLLQPLVNNSNPKFSDRVINYADTISSSRPEVAQLVGLPGDFSAAARFVRSYILSELMLEPKSNREAIFHAASIIANASVPPYEKSMTLWTTIKDLKNLTVAYKDNAVYQGTGPVGVYAMNIDNGYVTYDLNAMNFYDIPPAEQDSGLKVTSLNEIKQIIDMSAVVGLERQ
>NC_010336.1|WP_012280957.1|1792576_1792828_+|glutaredoxin
MTQQFNKIVLYRMVTPEKTCPYGLKAKALFEEKGWCFEDHILKTRAETDAFKHKYNLETTPLIFIDGKQIGGYSDLLEFLGQK
>NC_010336.1|WP_012280958.1|1792824_1793274_+|acyl-CoA-thioesterase
MNQQLKYFVLSTKVLPEHIDPNNHLNNIVYLQWMQDVAIEHVKANKVFDLTESQGLTWFAKKHTIEYLSQGFLDDDIAVVTWVESITKISTFRKYHIYRKSDKALLCKADTLWLMINAQKGRPAKIPTELVKIFDKYNDFEIDNIESLI
>NC_010336.1|WP_012280959.1|1793288_1793642_-|hypothetical-protein
MSKCKTHQNHEHKHQDNCGHTKIKHGDHYDYLHDGHLHHEHNGHYDEHTLDVTTKNPDECKPIKDECCDHVHGPDCGHEAVPHGDHIDYIVDDRLHHPHGNHCDDHGPVEVIKNNKK
>NC_010336.1|WP_012280960.1|1793670_1794423_-|RNA-methyltransferase
MKNLSQKLLKEIKKLHSPQGRKKSIYYIIEGLRCCDEAISRLPREDIIAIVTTGDRIDYPIDKKYILSEKDLNELTQTQNSQGVLILAKKKDTSSDFVFKDDFILVLDRIQDPGNIGTILRTAIAVGLTEIVLIDGTVDPFNPKAIRAGMGAQFSLKFRYFENLSAVRNYPTLKERKIWLTTPHEGVSCYSEEFKLSNSVLVFGEEANGIEDFSVGEKTMIPTLSNIESLNVAQAATIYLFEGLRQKMLK
>NC_010336.1|WP_012280961.1|1794560_1796507_+|BCCT-family-transporter
MQREKGAYAPVFYPAIILAIVLSLSGIFYPNQFASHIQNLQNLILEKFGWAYILAMSVFLCLCLILMFSRFGDIKLGQEHDLPEYSNISWFAMLFAAGMGIGLMFYGVAEPLKHFLAPPNMSSDELVLVKEAMNTTFFHWGIEAWSVYAIVGLSLAYFAYRHDLPLLPRSVLYPILGRHIYGPLGHAIDVFAVLGRLFGVATSLGFGAMQVSAGMSFLTGLPDTVNMQVIYIVVIVALATISVGLGLEKGIKALSNFNIILAVLLLVFILLLGNSSVLVRDYIQNIGYYLSTIVNQTFNLYAYNQENQEWLKSWTLFYWGWWIAWSPFVGMFIAKVSRGRTIRQFTIGVLFIPVGFTFLWMTVFGNSAIEIAMNGNGEALIDAANNNIPVALFEFLQHFPFSTLLSVLAVFLIVTFFVTSADSGALVIDILATGNAKKSITLQRIAWSVLSGLLAISLILAGGLQALQSATIISAFPLLFILFLMCVSLIKSLRLDYLRLKSIETHSTVVQFAKANTSWQKRLEAIAHKPSKDQAIEFLQKDVTTAIIEVADEMEKNGINTEVIRDHDHIQLAISIEGNEDFIYSVMLRSYQSKLGNYNRVEVLLSHGGQYYDIMGYSKDQVIADIVNQYDKHLHYLHLVVADKDILN
>NC_010336.1|WP_012280962.1|1796499_1796979_-|tryptophan-rich-sensory-protein
MNCNIKNKDYISLAAFIIVILGIGMSVGALTATSIPTWFAKLKYPFFAPPNWIFAPVWTILYIMIAISGWLVFKQKALREKVFIIYAIQLGLNFLWSFIFFCWHNIDLALLEISILWIFIAWNLKIFMDINKVAGYLLIPYLLWVGFAWILNLNYAMLN

You can click texts colored in the table to view more detailed information

Click the colored protein region to show detailed information

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity
NC_010336_2	2.1\|1788059\|29\|NC_010336\|PILER-CR,CRISPRCasFinder,CRT	1788059-1788087	29	NC_010336.1	1735617-1735645	0	1.0

1. spacer 2.1|1788059|29|NC_010336|PILER-CR,CRISPRCasFinder,CRT matches to position: 1735617-1735645, mismatch: 0, identity: 1.0

ctcatttagaaattcaatttttaaattct	CRISPR spacer
ctcatttagaaattcaatttttaaattct	Protospacer
*****************************

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NC_010336_2	2.1\|1788059\|29\|NC_010336\|PILER-CR,CRISPRCasFinder,CRT	1788059-1788087	29	MN694159	Marine virus AFVG_250M1044, complete genome	20327-20355	5	0.828
NC_010336_2	2.2\|1788124\|27\|NC_010336\|PILER-CR,CRISPRCasFinder,CRT	1788124-1788150	27	MG945151	UNVERIFIED: Microviridae sp. isolate 304-1801, partial genome	1734-1760	5	0.815
NC_010336_2	2.2\|1788124\|27\|NC_010336\|PILER-CR,CRISPRCasFinder,CRT	1788124-1788150	27	NC_022111	Prevotella sp. oral taxon 299 str. F0039 plasmid, complete sequence	1072658-1072684	5	0.815
NC_010336_2	2.4\|1788250\|28\|NC_010336\|PILER-CR,CRISPRCasFinder,CRT	1788250-1788277	28	NC_014756	Sulfuricurvum kujiense DSM 16994 plasmid pSULKU03, complete sequence	20842-20869	5	0.821
NC_010336_2	2.1\|1788059\|29\|NC_010336\|PILER-CR,CRISPRCasFinder,CRT	1788059-1788087	29	NZ_CP044300	Escherichia coli strain P59A plasmid pP59A-2, complete sequence	104021-104049	6	0.793
NC_010336_2	2.1\|1788059\|29\|NC_010336\|PILER-CR,CRISPRCasFinder,CRT	1788059-1788087	29	NZ_LR214939	Mycoplasma salivarium strain NCTC10113 plasmid 2	596237-596265	6	0.793
NC_010336_2	2.1\|1788059\|29\|NC_010336\|PILER-CR,CRISPRCasFinder,CRT	1788059-1788087	29	NC_011774	Bacillus cereus G9842 plasmid pG9842_140, complete sequence	92532-92560	6	0.793
NC_010336_2	2.1\|1788059\|29\|NC_010336\|PILER-CR,CRISPRCasFinder,CRT	1788059-1788087	29	KY363465	Providencia phage vB_PreS_PR1, complete genome	35810-35838	6	0.793
NC_010336_2	2.1\|1788059\|29\|NC_010336\|PILER-CR,CRISPRCasFinder,CRT	1788059-1788087	29	NZ_CP033045	Bacillus foraminis strain Bac44 plasmid unnamed, complete sequence	180669-180697	6	0.793
NC_010336_2	2.1\|1788059\|29\|NC_010336\|PILER-CR,CRISPRCasFinder,CRT	1788059-1788087	29	NC_019298	Rahnella sp. WMR121 plasmid pHW121, complete sequence	294-322	6	0.793
NC_010336_2	2.1\|1788059\|29\|NC_010336\|PILER-CR,CRISPRCasFinder,CRT	1788059-1788087	29	MG649967	Vibrio virus Thalassa, complete genome	43276-43304	6	0.793
NC_010336_2	2.1\|1788059\|29\|NC_010336\|PILER-CR,CRISPRCasFinder,CRT	1788059-1788087	29	MT708547	Klebsiella phage Muenster, complete genome	160237-160265	6	0.793
NC_010336_2	2.1\|1788059\|29\|NC_010336\|PILER-CR,CRISPRCasFinder,CRT	1788059-1788087	29	NC_042095	Vibrio phage Thalassa, complete genome	43276-43304	6	0.793
NC_010336_2	2.3\|1788187\|27\|NC_010336\|PILER-CR,CRISPRCasFinder,CRT	1788187-1788213	27	NZ_CP039931	Acinetobacter baumannii strain TG29392 plasmid pTG29392_1, complete sequence	12655-12681	6	0.778
NC_010336_2	2.3\|1788187\|27\|NC_010336\|PILER-CR,CRISPRCasFinder,CRT	1788187-1788213	27	KM359505	Prochlorococcus phage P-TIM68, complete genome	181646-181672	6	0.778
NC_010336_2	2.3\|1788187\|27\|NC_010336\|PILER-CR,CRISPRCasFinder,CRT	1788187-1788213	27	KX925554	Streptomyces phage BRock, complete genome	34659-34685	6	0.778
NC_010336_2	2.1\|1788059\|29\|NC_010336\|PILER-CR,CRISPRCasFinder,CRT	1788059-1788087	29	NZ_CP024873	Leptospira mayottensis 200901116 plasmid p1_L200901116, complete sequence	60313-60341	7	0.759
NC_010336_2	2.1\|1788059\|29\|NC_010336\|PILER-CR,CRISPRCasFinder,CRT	1788059-1788087	29	NZ_CP013276	Bacillus thuringiensis serovar israelensis strain AM65-52 plasmid pAM65-52-1-360K, complete sequence	103013-103041	7	0.759
NC_010336_2	2.1\|1788059\|29\|NC_010336\|PILER-CR,CRISPRCasFinder,CRT	1788059-1788087	29	NZ_CP039722	Bacillus thuringiensis strain BT-59 plasmid p1, complete sequence	240352-240380	7	0.759
NC_010336_2	2.1\|1788059\|29\|NC_010336\|PILER-CR,CRISPRCasFinder,CRT	1788059-1788087	29	NZ_CP009349	Bacillus thuringiensis HD1002 plasmid 1, complete sequence	179013-179041	7	0.759
NC_010336_2	2.1\|1788059\|29\|NC_010336\|PILER-CR,CRISPRCasFinder,CRT	1788059-1788087	29	NZ_CP045023	Bacillus thuringiensis strain JW-1 plasmid p1, complete sequence	103014-103042	7	0.759
NC_010336_2	2.1\|1788059\|29\|NC_010336\|PILER-CR,CRISPRCasFinder,CRT	1788059-1788087	29	MN694172	Marine virus AFVG_250M818, complete genome	32920-32948	7	0.759
NC_010336_2	2.4\|1788250\|28\|NC_010336\|PILER-CR,CRISPRCasFinder,CRT	1788250-1788277	28	KF751794	Campylobacter phage CJIE4-2, complete genome	9583-9610	7	0.75
NC_010336_2	2.4\|1788250\|28\|NC_010336\|PILER-CR,CRISPRCasFinder,CRT	1788250-1788277	28	KF751793	Campylobacter phage CJIE4-1, complete genome	11027-11054	7	0.75
NC_010336_2	2.1\|1788059\|29\|NC_010336\|PILER-CR,CRISPRCasFinder,CRT	1788059-1788087	29	NZ_LR215032	Mycoplasma gallopavonis strain NCTC10186 plasmid 2	150438-150466	8	0.724

1. spacer 2.1|1788059|29|NC_010336|PILER-CR,CRISPRCasFinder,CRT matches to MN694159 (Marine virus AFVG_250M1044, complete genome) position: , mismatch: 5, identity: 0.828

ctcatttagaaattcaatttttaaattct	CRISPR spacer
cttatttagaaattcaatatttactttat	Protospacer
**.*************** ****  ** *

2. spacer 2.2|1788124|27|NC_010336|PILER-CR,CRISPRCasFinder,CRT matches to MG945151 (UNVERIFIED: Microviridae sp. isolate 304-1801, partial genome) position: , mismatch: 5, identity: 0.815

aaccctaaagattctaacggtgttatt	CRISPR spacer
gtgcctaaaggttctaccggtgttatt	Protospacer
.  *******.***** **********

3. spacer 2.2|1788124|27|NC_010336|PILER-CR,CRISPRCasFinder,CRT matches to NC_022111 (Prevotella sp. oral taxon 299 str. F0039 plasmid, complete sequence) position: , mismatch: 5, identity: 0.815

aaccctaaagattctaacggtgttatt	CRISPR spacer
caactcaaagatactaacggtgttatt	Protospacer
 * *..****** **************

4. spacer 2.4|1788250|28|NC_010336|PILER-CR,CRISPRCasFinder,CRT matches to NC_014756 (Sulfuricurvum kujiense DSM 16994 plasmid pSULKU03, complete sequence) position: , mismatch: 5, identity: 0.821

ggactattcttttaatgtttgatacata	CRISPR spacer
agaagattcttttaatttttgagacata	Protospacer
.**  *********** ***** *****

5. spacer 2.1|1788059|29|NC_010336|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP044300 (Escherichia coli strain P59A plasmid pP59A-2, complete sequence) position: , mismatch: 6, identity: 0.793

ctcatttagaaattcaatttttaaattct	CRISPR spacer
gagatttagaaatccattttttaaattca	Protospacer
   **********.** ***********

6. spacer 2.1|1788059|29|NC_010336|PILER-CR,CRISPRCasFinder,CRT matches to NZ_LR214939 (Mycoplasma salivarium strain NCTC10113 plasmid 2) position: , mismatch: 6, identity: 0.793

ctcatttagaaattcaatttttaaattct	CRISPR spacer
atcatttagaaattaaattttttaatgag	Protospacer
 ************* ******* ***

7. spacer 2.1|1788059|29|NC_010336|PILER-CR,CRISPRCasFinder,CRT matches to NC_011774 (Bacillus cereus G9842 plasmid pG9842_140, complete sequence) position: , mismatch: 6, identity: 0.793

ctcatttagaaattcaatttttaaattct	CRISPR spacer
tttatttagaaattctctttttaaataca	Protospacer
.*.************  ********* *

8. spacer 2.1|1788059|29|NC_010336|PILER-CR,CRISPRCasFinder,CRT matches to KY363465 (Providencia phage vB_PreS_PR1, complete genome) position: , mismatch: 6, identity: 0.793

ctcatttagaaattcaatttttaaattct	CRISPR spacer
attatttaaaaattcaattgttaaatacc	Protospacer
 *.*****.********** ****** *.

9. spacer 2.1|1788059|29|NC_010336|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP033045 (Bacillus foraminis strain Bac44 plasmid unnamed, complete sequence) position: , mismatch: 6, identity: 0.793

ctcatttagaaattcaattttt---aaattct	CRISPR spacer
atcatttagaaattcaacttttcggaaac---	Protospacer
 ****************.****   ***.

10. spacer 2.1|1788059|29|NC_010336|PILER-CR,CRISPRCasFinder,CRT matches to NC_019298 (Rahnella sp. WMR121 plasmid pHW121, complete sequence) position: , mismatch: 6, identity: 0.793

ctcatttagaaattcaatttttaaattct	CRISPR spacer
agcttttagaaatgcattttttaaatttt	Protospacer
  * ********* ** **********.*

11. spacer 2.1|1788059|29|NC_010336|PILER-CR,CRISPRCasFinder,CRT matches to MG649967 (Vibrio virus Thalassa, complete genome) position: , mismatch: 6, identity: 0.793

ctcatttagaaattcaatttttaaattct	CRISPR spacer
gtaattgagcaattcaatttttaaatctt	Protospacer
 * *** ** ****************..*

12. spacer 2.1|1788059|29|NC_010336|PILER-CR,CRISPRCasFinder,CRT matches to MT708547 (Klebsiella phage Muenster, complete genome) position: , mismatch: 6, identity: 0.793

ctcatttagaaattcaatttttaaattct	CRISPR spacer
atcctaatgaaattcaatttttaaaatct	Protospacer
 ** *   ***************** ***

13. spacer 2.1|1788059|29|NC_010336|PILER-CR,CRISPRCasFinder,CRT matches to NC_042095 (Vibrio phage Thalassa, complete genome) position: , mismatch: 6, identity: 0.793

ctcatttagaaattcaatttttaaattct	CRISPR spacer
gtaattgagcaattcaatttttaaatctt	Protospacer
 * *** ** ****************..*

14. spacer 2.3|1788187|27|NC_010336|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP039931 (Acinetobacter baumannii strain TG29392 plasmid pTG29392_1, complete sequence) position: , mismatch: 6, identity: 0.778

gaaatggtggagtaatgccaagcaacg	CRISPR spacer
caaatggtggactaatgccaatcacaa	Protospacer
 ********** ********* **  .

15. spacer 2.3|1788187|27|NC_010336|PILER-CR,CRISPRCasFinder,CRT matches to KM359505 (Prochlorococcus phage P-TIM68, complete genome) position: , mismatch: 6, identity: 0.778

gaaatggtggagtaatgccaagcaacg	CRISPR spacer
taaatggtggaatgatgccaagcattc	Protospacer
 **********.*.********** .

16. spacer 2.3|1788187|27|NC_010336|PILER-CR,CRISPRCasFinder,CRT matches to KX925554 (Streptomyces phage BRock, complete genome) position: , mismatch: 6, identity: 0.778

gaaatggtggagtaatgccaagcaacg	CRISPR spacer
ttgttggtggagtagtgcccagcaacg	Protospacer
  . **********.**** *******

17. spacer 2.1|1788059|29|NC_010336|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP024873 (Leptospira mayottensis 200901116 plasmid p1_L200901116, complete sequence) position: , mismatch: 7, identity: 0.759

ctcatttagaaattcaatttttaaattct	CRISPR spacer
aacccttagaaattcaatttttccattcc	Protospacer
  * .*****************  ****.

18. spacer 2.1|1788059|29|NC_010336|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP013276 (Bacillus thuringiensis serovar israelensis strain AM65-52 plasmid pAM65-52-1-360K, complete sequence) position: , mismatch: 7, identity: 0.759

ctcatttagaaattcaatttttaaattct	CRISPR spacer
aacattttaaaattcaatttttaaaagat	Protospacer
  ***** .****************   *

19. spacer 2.1|1788059|29|NC_010336|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP039722 (Bacillus thuringiensis strain BT-59 plasmid p1, complete sequence) position: , mismatch: 7, identity: 0.759

ctcatttagaaattcaatttttaaattct	CRISPR spacer
aacattttaaaattcaatttttaaaagat	Protospacer
  ***** .****************   *

20. spacer 2.1|1788059|29|NC_010336|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP009349 (Bacillus thuringiensis HD1002 plasmid 1, complete sequence) position: , mismatch: 7, identity: 0.759

ctcatttagaaattcaatttttaaattct	CRISPR spacer
aacattttaaaattcaatttttaaaagat	Protospacer
  ***** .****************   *

21. spacer 2.1|1788059|29|NC_010336|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP045023 (Bacillus thuringiensis strain JW-1 plasmid p1, complete sequence) position: , mismatch: 7, identity: 0.759

ctcatttagaaattcaatttttaaattct	CRISPR spacer
aacattttaaaattcaatttttaaaagat	Protospacer
  ***** .****************   *

22. spacer 2.1|1788059|29|NC_010336|PILER-CR,CRISPRCasFinder,CRT matches to MN694172 (Marine virus AFVG_250M818, complete genome) position: , mismatch: 7, identity: 0.759

ctcatttagaaattcaatttttaaattct	CRISPR spacer
agcttttggaaattctatttttaaattag	Protospacer
  * ***.******* ***********

23. spacer 2.4|1788250|28|NC_010336|PILER-CR,CRISPRCasFinder,CRT matches to KF751794 (Campylobacter phage CJIE4-2, complete genome) position: , mismatch: 7, identity: 0.75

ggactattcttttaatgtttgatacata	CRISPR spacer
atcaaattcttttaatgtttgagatata	Protospacer
.    ***************** *.***

24. spacer 2.4|1788250|28|NC_010336|PILER-CR,CRISPRCasFinder,CRT matches to KF751793 (Campylobacter phage CJIE4-1, complete genome) position: , mismatch: 7, identity: 0.75

ggactattcttttaatgtttgatacata	CRISPR spacer
atcaaattcttttaatgtttgagatata	Protospacer
.    ***************** *.***

25. spacer 2.1|1788059|29|NC_010336|PILER-CR,CRISPRCasFinder,CRT matches to NZ_LR215032 (Mycoplasma gallopavonis strain NCTC10186 plasmid 2) position: , mismatch: 8, identity: 0.724

ctcatttagaaattcaatttttaaattct	CRISPR spacer
aaaatttagaaattcaatttaaaaataaa	Protospacer
   *****************  ****

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

138102 : 202237

Staphylococcus_prophage(27.78%)

tRNA,transposase,protease

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_012279618.1\|138102_139047_+\|transposase	IS30 family transposase	Q9MBM9	Staphylococcus_prophage	7.0e-38	34.8
WP_012279618.1\|139670_140615_+\|transposase	IS30 family transposase	Q9MBM9	Staphylococcus_prophage	7.0e-38	34.8
WP_003015139.1\|140851_141973_+	ABC transporter ATP-binding protein	G3M9Y6	Bacillus_virus	1.5e-31	39.2
WP_012279684.1\|141972_142854_+	ABC transporter permease subunit	NA	NA	NA	NA
WP_012279685.1\|142866_143670_+	ABC transporter permease subunit	NA	NA	NA	NA
WP_012279686.1\|143675_144272_-	LysE family translocator	NA	NA	NA	NA
WP_004288034.1\|144400_144655_-	50S ribosomal protein L27	NA	NA	NA	NA
WP_004288036.1\|144685_145000_-	50S ribosomal protein L21	NA	NA	NA	NA
WP_041268133.1\|145219_145786_-	DNA-3-methyladenine glycosylase I	NA	NA	NA	NA
WP_012279688.1\|145969_146515_+	hypothetical protein	NA	NA	NA	NA
WP_012279689.1\|146685_149409_-	preprotein translocase subunit SecA	NA	NA	NA	NA
WP_144402763.1\|149568_150591_+	hypothetical protein	NA	NA	NA	NA
WP_012279691.1\|150597_151038_+	hypothetical protein	NA	NA	NA	NA
WP_004288043.1\|151043_151766_-	purine-nucleoside phosphorylase	NA	NA	NA	NA
WP_012279692.1\|151969_153919_-\|protease	ATP-dependent zinc metalloprotease FtsH	H8ZJI5	Ostreococcus_tauri_virus	4.7e-113	42.1
WP_012279693.1\|154120_155512_+	MFS transporter	A0A0M3UL24	Mycobacterium_phage	1.7e-08	25.9
WP_012279694.1\|155512_158335_-	excinuclease ABC subunit UvrA	A0A1B1IVR3	uncultured_Mediterranean_phage	5.2e-312	56.5
WP_004288047.1\|158372_158855_-	transcription elongation factor GreA	NA	NA	NA	NA
WP_012279695.1\|158891_159476_-	prepilin-type N-terminal cleavage/methylation domain-containing protein	NA	NA	NA	NA
WP_012279696.1\|159475_161098_-	glucose-6-phosphate isomerase	NA	NA	NA	NA
WP_004288050.1\|161084_161738_-	thiamine diphosphokinase	NA	NA	NA	NA
WP_004288051.1\|161799_163260_-	IMP dehydrogenase	A0A1V0SHK8	Klosneuvirus	6.3e-94	40.4
WP_004288052.1\|163363_164803_-	leucyl aminopeptidase	Q6GYZ8	Mycoplasma_phage	1.9e-55	36.1
WP_012279697.1\|164968_166051_+	LPS export ABC transporter permease LptF	NA	NA	NA	NA
WP_004288054.1\|166051_167110_+	LPS export ABC transporter permease LptG	NA	NA	NA	NA
WP_012279698.1\|167119_168373_+	insulinase family protein	G3MBJ8	Bacillus_virus	6.7e-28	25.0
WP_012279699.1\|168378_169602_+	insulinase family protein	NA	NA	NA	NA
WP_012279700.1\|169602_170181_+	16S rRNA (guanine(966)-N(2))-methyltransferase RsmD	NA	NA	NA	NA
WP_004288058.1\|170213_170864_+	trimeric intracellular cation channel family protein	NA	NA	NA	NA
WP_004288059.1\|170922_171531_-\|tRNA	tRNA-(ms[2]io[6]A)-hydroxylase	NA	NA	NA	NA
WP_004288060.1\|171643_172447_+	uridine phosphorylase	NA	NA	NA	NA
WP_012279701.1\|172463_172865_+	cytidine deaminase	NA	NA	NA	NA
WP_012279702.1\|173174_176207_-	FAD-binding oxidoreductase	NA	NA	NA	NA
WP_012279703.1\|176419_177958_+	2,3-bisphosphoglycerate-independent phosphoglycerate mutase	NA	NA	NA	NA
WP_012279704.1\|177972_179253_+\|tRNA	serine--tRNA ligase	A0A1B1IVT2	uncultured_Mediterranean_phage	5.1e-100	58.4
WP_012279705.1\|179353_180250_+	ROK family protein	NA	NA	NA	NA
WP_012279706.1\|180335_181595_+	oligosaccharide flippase family protein	NA	NA	NA	NA
WP_012279707.1\|181597_181801_-	hypothetical protein	NA	NA	NA	NA
WP_012279708.1\|181820_182225_-	hypothetical protein	NA	NA	NA	NA
WP_012279709.1\|182271_182505_-	hypothetical protein	NA	NA	NA	NA
WP_012279710.1\|182697_184479_+	cysteine/glutathione ABC transporter permease/ATP-binding protein CydD	A0A1V0SE00	Indivirus	5.1e-29	35.0
WP_012279711.1\|184475_186125_+	cysteine/glutathione ABC transporter ATP-binding protein/permease CydC	A0A1V0SE00	Indivirus	1.3e-26	29.9
WP_012279618.1\|186379_187324_+\|transposase	IS30 family transposase	Q9MBM9	Staphylococcus_prophage	7.0e-38	34.8
WP_012279712.1\|190612_190840_+	DUF2188 domain-containing protein	NA	NA	NA	NA
WP_012279713.1\|190854_191364_+	hypothetical protein	NA	NA	NA	NA
WP_041268064.1\|191355_191874_-	hypothetical protein	NA	NA	NA	NA
WP_041268065.1\|191836_192319_-	DUF3644 domain-containing protein	A0A0N9RUA4	Staphylococcus_phage	7.1e-10	33.6
WP_012279714.1\|192321_192567_-	restriction endonuclease subunit S	NA	NA	NA	NA
WP_012279618.1\|192686_193631_+\|transposase	IS30 family transposase	Q9MBM9	Staphylococcus_prophage	7.0e-38	34.8
WP_012279715.1\|193602_194574_-	restriction endonuclease subunit S	NA	NA	NA	NA
WP_012279716.1\|194633_196229_-	type I restriction-modification system subunit M	A0A220A2U4	Liberibacter_phage	1.4e-49	31.3
WP_012279717.1\|196322_197573_-	C4-dicarboxylate transporter DctA	NA	NA	NA	NA
WP_012279718.1\|197713_198238_+	hypothetical protein	NA	NA	NA	NA
WP_004288078.1\|198260_198641_-	RidA family protein	NA	NA	NA	NA
WP_012279719.1\|198640_200185_-	SulP family inorganic anion transporter	A0A2H4J153	uncultured_Caudovirales_phage	3.4e-82	38.1
WP_012279618.1\|201292_202237_-\|transposase	IS30 family transposase	Q9MBM9	Staphylococcus_prophage	7.0e-38	34.8

DBSCAN-SWA_2

464852 : 473909

Klosneuvirus(16.67%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_012279903.1\|464852_466859_+	M3 family metallopeptidase	A0A1V0SID3	Klosneuvirus	6.5e-49	26.5
WP_012279904.1\|466951_467305_+	YraN family protein	NA	NA	NA	NA
WP_012279905.1\|467301_468399_-	5-(carboxyamino)imidazole ribonucleotide synthase	NA	NA	NA	NA
WP_012279906.1\|468400_468892_-	5-(carboxyamino)imidazole ribonucleotide mutase	A0A2P0VNU7	Tetraselmis_virus	9.1e-21	42.5
WP_012279907.1\|469015_469591_-	phosphoribosylglycinamide formyltransferase	E3SNR5	Prochlorococcus_phage	5.6e-22	36.9
WP_012279908.1\|469593_471903_-	phosphoribosylaminoimidazolesuccinocarboxamide synthase	A0A0M4JBD3	Mollivirus	3.1e-26	31.3
WP_012279909.1\|471902_472946_-	phosphoribosylformylglycinamidine cyclo-ligase	A0A1D7SQF5	Cyanophage	2.9e-53	35.7
WP_012279910.1\|473060_473909_-	bifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase FolD	A0A249XZQ2	Enterococcus_phage	1.4e-32	40.7

DBSCAN-SWA_3

752952 : 762621

Indivirus(28.57%)

tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_012280144.1\|752952_754203_-	sodium:proton antiporter	A0A2H4J178	uncultured_Caudovirales_phage	1.3e-26	31.8
WP_012280145.1\|754732_755803_+	bifunctional diaminohydroxyphosphoribosylaminopyrimidine deaminase/5-amino-6-(5-phosphoribosylamino)uracil reductase RibD	A0A1V0SE20	Indivirus	7.0e-50	37.7
WP_012280146.1\|755795_756401_+	riboflavin synthase	A0A1V0SE20	Indivirus	3.8e-21	38.0
WP_012280147.1\|756393_757605_+	3,4-dihydroxy-2-butanone-4-phosphate synthase	A0A2H4PQS2	Staphylococcus_phage	4.7e-87	44.3
WP_012280148.1\|757608_758052_+	6,7-dimethyl-8-ribityllumazine synthase	A0A2H4PQS3	Staphylococcus_phage	4.2e-25	43.6
WP_012280149.1\|758055_758574_+	peptide deformylase	A0A067XQZ3	Caulobacter_phage	3.4e-18	39.8
WP_012280150.1\|758670_759615_+	hypothetical protein	NA	NA	NA	NA
WP_012280151.1\|759643_760723_-\|tRNA	tRNA 2-thiouridine(34) synthase MnmA	NA	NA	NA	NA
WP_012280152.1\|760836_762621_-	elongation factor 4	A0A2K9L6L3	Tupanvirus	4.2e-23	43.2

DBSCAN-SWA_4

1361926 : 1370084

Enterobacteria_phage(28.57%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_012280619.1\|1361926_1363300_+	mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase	A0A1V0SH58	Hokovirus	2.7e-54	31.0
WP_012280620.1\|1363339_1364479_+	GDP-mannose 4,6-dehydratase	M1HAR7	Acanthocystis_turfacea_Chlorella_virus	9.5e-122	59.4
WP_012280621.1\|1364525_1364810_+	four helix bundle protein	NA	NA	NA	NA
WP_012280622.1\|1364902_1366042_+	GDP-L-fucose synthase	D1LW79	Prochlorococcus_phage	2.4e-88	46.1
WP_012280623.1\|1366172_1367063_+	glucose-1-phosphate thymidylyltransferase RfbA	I7I009	Enterobacteria_phage	1.0e-102	61.3
WP_012280624.1\|1367059_1367632_+	dTDP-4-dehydrorhamnose 3,5-epimerase	I7HJC4	Enterobacteria_phage	2.8e-37	52.6
WP_012280625.1\|1367787_1368693_+	dTDP-4-dehydrorhamnose reductase	A0A1D8EQE2	Escherichia_phage	1.1e-40	39.0
WP_012280626.1\|1369082_1370084_+	dTDP-glucose 4,6-dehydratase	K7QJG5	Escherichia_phage	4.2e-81	49.1

DBSCAN-SWA_5

1629428 : 1673774

Staphylococcus_prophage(26.67%)

tRNA,transposase,protease

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_012279618.1\|1629428_1630373_+\|transposase	IS30 family transposase	Q9MBM9	Staphylococcus_prophage	7.0e-38	34.8
WP_012280832.1\|1630344_1630719_-	hydroxy/aromatic amino acid permease (HAAAP) family protein	NA	NA	NA	NA
WP_012280833.1\|1630800_1632273_-	MetQ/NlpA family lipoprotein	NA	NA	NA	NA
WP_012280834.1\|1632250_1633303_-	ATP-binding cassette domain-containing protein	G9BWD6	Planktothrix_phage	4.6e-30	37.4
WP_012280835.1\|1633289_1633904_-	glycerol-3-phosphate 1-O-acyltransferase PlsY	NA	NA	NA	NA
WP_012280836.1\|1634056_1635163_+\|tRNA	tRNA guanosine(34) transglycosylase Tgt	A0A1B1IVQ4	uncultured_Mediterranean_phage	4.6e-97	49.7
WP_012280837.1\|1635202_1636165_-	LysR family transcriptional regulator	NA	NA	NA	NA
WP_012279618.1\|1636624_1637569_-\|transposase	IS30 family transposase	Q9MBM9	Staphylococcus_prophage	7.0e-38	34.8
WP_041268112.1\|1638112_1638706_+	cysteine hydrolase	NA	NA	NA	NA
WP_004287530.1\|1638769_1638973_+	hypothetical protein	NA	NA	NA	NA
WP_012280841.1\|1639117_1640341_+	MFS transporter	NA	NA	NA	NA
WP_012280842.1\|1640351_1641800_+	hypothetical protein	NA	NA	NA	NA
WP_004287533.1\|1641933_1642290_+	preprotein translocase subunit YajC	A0A1B1IVR5	uncultured_Mediterranean_phage	2.6e-09	50.0
WP_012280843.1\|1642347_1644285_+	protein translocase subunit SecD	NA	NA	NA	NA
WP_012280844.1\|1644303_1645245_+	protein translocase subunit SecF	A0A1B1IVP7	uncultured_Mediterranean_phage	7.7e-45	39.8
WP_012280845.1\|1645316_1645805_+	SH3 domain-containing protein	NA	NA	NA	NA
WP_012280846.1\|1645830_1646709_+	RNA polymerase sigma factor RpoH	A0A248SJA5	Salicola_phage	1.2e-39	38.2
WP_012280847.1\|1646798_1648079_+	3-phosphoshikimate 1-carboxyvinyltransferase	NA	NA	NA	NA
WP_004287539.1\|1648078_1648678_+	hypothetical protein	NA	NA	NA	NA
WP_012280848.1\|1648652_1649111_+	ribonuclease HI	A0A1S5XYT5	Kurlavirus	4.8e-32	50.7
WP_012280849.1\|1649113_1650145_+	asparaginase	NA	NA	NA	NA
WP_012280850.1\|1650232_1650937_+	carbonic anhydrase	NA	NA	NA	NA
WP_012280851.1\|1651010_1653359_+	DEAD/DEAH box helicase family protein	A0A2P1MXB6	Escherichia_phage	7.4e-12	23.0
WP_012279618.1\|1654040_1654985_+\|transposase	IS30 family transposase	Q9MBM9	Staphylococcus_prophage	7.0e-38	34.8
WP_012280853.1\|1655041_1655560_+	hypothetical protein	NA	NA	NA	NA
WP_012280854.1\|1655890_1657114_+	type I restriction-modification system subunit S	NA	NA	NA	NA
WP_041268195.1\|1657433_1658048_+	hypothetical protein	NA	NA	NA	NA
WP_012280856.1\|1658028_1658349_+	type I restriction-modification system subunit M (methyltransferase)	NA	NA	NA	NA
WP_012279618.1\|1658345_1659290_-\|transposase	IS30 family transposase	Q9MBM9	Staphylococcus_prophage	7.0e-38	34.8
WP_012280858.1\|1660515_1660980_-	hypothetical protein	NA	NA	NA	NA
WP_012280859.1\|1661132_1662449_+	trigger factor	NA	NA	NA	NA
WP_004287550.1\|1662474_1663080_+	ATP-dependent Clp endopeptidase proteolytic subunit ClpP	A0A223W000	Agrobacterium_phage	2.2e-56	56.3
WP_012280860.1\|1663104_1664358_+\|protease	ATP-dependent Clp protease ATP-binding subunit ClpX	G3M9Z9	Bacillus_virus	5.9e-125	53.8
WP_012280861.1\|1664383_1666708_+	endopeptidase La	A0A0R6PGP8	Moraxella_phage	2.9e-194	47.7
WP_004287553.1\|1666793_1667066_+	HU family DNA-binding protein	Q6QIE5	Burkholderia_phage	1.9e-20	58.9
WP_012280862.1\|1667177_1668611_+	hypothetical protein	NA	NA	NA	NA
WP_012280863.1\|1668611_1669538_+\|tRNA	tRNA (adenosine(37)-N6)-dimethylallyltransferase MiaA	NA	NA	NA	NA
WP_004287556.1\|1669642_1669972_+	RNA chaperone Hfq	NA	NA	NA	NA
WP_012280864.1\|1670019_1671327_+	GTPase HflX	NA	NA	NA	NA
WP_004287559.1\|1672706_1673774_+\|protease	FtsH protease activity modulator HflK	NA	NA	NA	NA

DBSCAN-SWA_6

1869001 : 1876869

Enterobacteria_phage(33.33%)

transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_012281025.1\|1869001_1869568_+	dCTP deaminase	S5VM63	Pseudomonas_phage	6.4e-71	73.5
WP_144402771.1\|1869937_1871575_-\|transposase	Tn3 family transposase	Q1MVP5	Enterobacteria_phage	9.6e-59	29.5
WP_012279618.1\|1871616_1872561_-\|transposase	IS30 family transposase	Q9MBM9	Staphylococcus_prophage	7.0e-38	34.8
WP_144402770.1\|1872628_1873333_-	hypothetical protein	NA	NA	NA	NA
WP_012281028.1\|1873434_1873848_-	DUF4158 domain-containing protein	NA	NA	NA	NA
WP_012281029.1\|1873844_1874414_-	recombinase family protein	A0A0A7NPV4	Enterobacteria_phage	8.0e-37	46.2
WP_012281031.1\|1874689_1875109_+	arsenate reductase (glutaredoxin)	A0A2H4J8T1	uncultured_Caudovirales_phage	9.1e-30	49.3
WP_012281032.1\|1875288_1876869_+	SulP family inorganic anion transporter	A0A2H4J153	uncultured_Caudovirales_phage	2.7e-74	37.3

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. NC_010336

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection