CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NC_010511	Methylobacterium sp. 4-46, complete sequence	36 crisprs	csa3,DEDDh,cas3HD,cas3,cas5,cas8c,cas7b,cas1,cas2	15	20	11	6
NC_010374	Methylobacterium sp. 4-46 plasmid pM44602, complete sequence	0 crisprs	NA	0	0	0	0
NC_010373	Methylobacterium sp. 4-46 plasmid pM44601, complete sequence	0 crisprs	NA	0	0	0	0

Results visualization

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CRISPR-Cas detection and classification

Crispr_ID: NC_010511_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_010511_1

288535-288644

Orphan

Consensus_repeat	Method
TGACGAGCCCGCGCGGCACTTGAGCGAAGCCGACATCCGCAT	CRISPRCasFinder

1 spacers

The CRISPR arrays of NC_010511_1

>merge|NC_010511|1|288535-288644|CRISPRCasFinder
TGACGAGCCCGCGCGGCACTTGAGCGAAGCCGACATCCGCATTGCGGAGCAATCCGTCGGATGTCGTATGACGAGCCCGCGCGGCGCTTGAGCGAAGCCGACATCCGCAT

>NC_010511|1|1|288535-288644|CRISPRCasFinder
TGACGAGCCCGCGCGGCACTTGAGCGAAGCCGACATCCGCAT	TGCGGAGCAATCCGTCGGATGTCGTA
TGACGAGCCCGCGCGGCGCTTGAGCGAAGCCGACATCCGCAT

Protein	Signature genes	Signature genes Name	Protein_function
NC_010511.1\|WP_043701977.1\|288684_290403_+\|AMP-binding-protein	unknown	unknown	gnl\|CDD\|223395
NC_010511.1\|WP_012330233.1\|297666_299910_+\|hybrid-sensor-histidine-kinase/response-regulator	unknown	unknown	gnl\|CDD\|223716
NC_010511.1\|WP_012330226.1\|287692_288460_+\|SDR-family-oxidoreductase	unknown	unknown	gnl\|CDD\|235975
NC_010511.1\|WP_012330224.1\|284087_286163_-\|3-hydroxyacyl-CoA-dehydrogenase	unknown	unknown	gnl\|CDD\|236864
NC_010511.1\|WP_083784615.1\|295112_295850_+\|chemotaxis-protein-CheW	unknown	unknown	gnl\|CDD\|366716
NC_010511.1\|WP_012330231.1\|293658_295116_+\|protein-glutamate-methyltransferase	unknown	unknown	gnl\|CDD\|224271
NC_010511.1\|WP_043701974.1\|280314_281424_-\|GTP-binding-protein	unknown	unknown	gnl\|CDD\|223597
NC_010511.1\|WP_012330223.1\|282818_284021_-\|pimeloyl-CoA-dehydrogenase-large-subunit	unknown	unknown	gnl\|CDD\|132248
NC_010511.1\|WP_012330235.1\|301083_302805_+\|response-regulator	unknown	unknown	gnl\|CDD\|236901
NC_010511.1\|WP_012330230.1\|293179_293671_+\|chemotaxis-protein-CheW	unknown	unknown	gnl\|CDD\|223905
NC_010511.1\|WP_012330220.1\|279252_280188_-\|hypothetical-protein	unknown	unknown	unknown
NC_010511.1\|WP_012330229.1\|291049_292828_-\|acetolactate-synthase-3-large-subunit	unknown	unknown	gnl\|CDD\|236380
NC_010511.1\|WP_012330219.1\|278843_279164_+\|HPr-family-phosphocarrier-protein	unknown	unknown	gnl\|CDD\|224836
NC_010511.1\|WP_012330232.1\|295873_297559_+\|methyl-accepting-chemotaxis-protein	unknown	unknown	gnl\|CDD\|223910
NC_010511.1\|WP_012330225.1\|286261_287464_-\|acetyl-CoA-C-acyltransferase	unknown	unknown	gnl\|CDD\|180843
NC_010511.1\|WP_012330222.1\|281529_282678_-\|acyl-CoA-dehydrogenase	unknown	unknown	gnl\|CDD\|132247
NC_010511.1\|WP_012330228.1\|290488_291031_-\|acetolactate-synthase-small-subunit	unknown	unknown	gnl\|CDD\|183365
NC_010511.1\|WP_012330234.1\|300019_301087_+\|chemotaxis-specific-protein-glutamate-methyltransferase-CheB	unknown	unknown	gnl\|CDD\|234828
NC_010511.1\|WP_012330218.1\|278356_278758_+\|PTS-sugar-transporter-subunit-IIA	unknown	unknown	gnl\|CDD\|225446
NC_010511.1\|WP_085984455.1\|277805_278267_+\|serine-kinase	unknown	unknown	gnl\|CDD\|238899

Protein	Function_ID	Function_description	E-value
NC_010511.1\|WP_043701977.1\|288684_290403_+\|AMP-binding-protein	gnl\|CDD\|223395	COG0318, CaiC, Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II [Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism].	1.02247e-155
NC_010511.1\|WP_012330233.1\|297666_299910_+\|hybrid-sensor-histidine-kinase/response-regulator	gnl\|CDD\|223716	COG0643, CheA, Chemotaxis protein histidine kinase and related kinases [Cell motility and secretion / Signal transduction mechanisms].	4.33953e-66
NC_010511.1\|WP_012330226.1\|287692_288460_+\|SDR-family-oxidoreductase	gnl\|CDD\|235975	PRK07231, FabG-like, SDR family oxidoreductase.	4.28669e-93
NC_010511.1\|WP_012330224.1\|284087_286163_-\|3-hydroxyacyl-CoA-dehydrogenase	gnl\|CDD\|236864	PRK11154, fadJ, fatty acid oxidation complex subunit alpha FadJ.	7.30911e-162
NC_010511.1\|WP_083784615.1\|295112_295850_+\|chemotaxis-protein-CheW	gnl\|CDD\|366716	pfam01584, CheW, CheW-like domain. CheW proteins are part of the chemotaxis signaling mechanism in bacteria. CheW interacts with the methyl accepting chemotaxis proteins (MCPs) and relays signals to CheY, which affects flageller rotation. This family includes CheW and other related proteins that are involved in chemotaxis. The CheW-like regulatory domain in CheA binds to CheW, suggesting that these domains can interact with each other.	1.20331e-17
NC_010511.1\|WP_012330231.1\|293658_295116_+\|protein-glutamate-methyltransferase	gnl\|CDD\|224271	COG1352, CheR, Methylase of chemotaxis methyl-accepting proteins [Cell motility and secretion / Signal transduction mechanisms].	1.63167e-76
NC_010511.1\|WP_043701974.1\|280314_281424_-\|GTP-binding-protein	gnl\|CDD\|223597	COG0523, COG0523, Putative GTPases (G3E family) [General function prediction only].	5.8294e-99
NC_010511.1\|WP_012330223.1\|282818_284021_-\|pimeloyl-CoA-dehydrogenase-large-subunit	gnl\|CDD\|132248	TIGR03204, pimC_large, pimeloyl-CoA dehydrogenase, large subunit. Members of this protein family are the PimC proteins of species such as Rhodopseudomonas palustris and Bradyrhizobium japonicum. The pimFABCDE operon encodes proteins for the metabolism of straight chain dicarboxylates of seven to fourteen carbons. Especially relevant is pimeloyl-CoA, basis of the gene symbol, as it is a catabolite of benzoyl-CoA degradation, which occurs in Rhodopseudomonas palustris.	0
NC_010511.1\|WP_012330235.1\|301083_302805_+\|response-regulator	gnl\|CDD\|236901	PRK11360, PRK11360, two-component system sensor histidine kinase AtoS.	1.9816e-49
NC_010511.1\|WP_012330230.1\|293179_293671_+\|chemotaxis-protein-CheW	gnl\|CDD\|223905	COG0835, CheW, Chemotaxis signal transduction protein [Cell motility and secretion / Signal transduction mechanisms].	3.49303e-15
NC_010511.1\|WP_012330229.1\|291049_292828_-\|acetolactate-synthase-3-large-subunit	gnl\|CDD\|236380	PRK09107, PRK09107, acetolactate synthase 3 catalytic subunit; Validated.	0
NC_010511.1\|WP_012330219.1\|278843_279164_+\|HPr-family-phosphocarrier-protein	gnl\|CDD\|224836	COG1925, FruB, Phosphotransferase system, HPr-related proteins [Carbohydrate transport and metabolism].	1.23795e-29
NC_010511.1\|WP_012330232.1\|295873_297559_+\|methyl-accepting-chemotaxis-protein	gnl\|CDD\|223910	COG0840, Tar, Methyl-accepting chemotaxis protein [Cell motility and secretion / Signal transduction mechanisms].	1.48875e-49
NC_010511.1\|WP_012330225.1\|286261_287464_-\|acetyl-CoA-C-acyltransferase	gnl\|CDD\|180843	PRK07108, PRK07108, acetyl-CoA C-acyltransferase.	0
NC_010511.1\|WP_012330222.1\|281529_282678_-\|acyl-CoA-dehydrogenase	gnl\|CDD\|132247	TIGR03203, pimD_small, pimeloyl-CoA dehydrogenase, small subunit. Members of this protein family are the PimD proteins of species such as Rhodopseudomonas palustris, Bradyrhizobium japonicum. The pimFABCDE operon encodes proteins for the metabolism of straight chain dicarboxylates of seven to fourteen carbons. Especially relevant is pimeloyl-CoA, basis of the gene symbol, as it is a catabolite of benzoyl-CoA degradation, which occurs in Rhodopseudomonas palustris.	1.83757e-174
NC_010511.1\|WP_012330228.1\|290488_291031_-\|acetolactate-synthase-small-subunit	gnl\|CDD\|183365	PRK11895, ilvH, acetolactate synthase 3 regulatory subunit; Reviewed.	3.54583e-79
NC_010511.1\|WP_012330234.1\|300019_301087_+\|chemotaxis-specific-protein-glutamate-methyltransferase-CheB	gnl\|CDD\|234828	PRK00742, PRK00742, chemotaxis-specific protein-glutamate methyltransferase CheB.	3.93354e-111
NC_010511.1\|WP_012330218.1\|278356_278758_+\|PTS-sugar-transporter-subunit-IIA	gnl\|CDD\|225446	COG2893, ManX, Phosphotransferase system, mannose/fructose-specific component IIA [Carbohydrate transport and metabolism].	6.03202e-39
NC_010511.1\|WP_085984455.1\|277805_278267_+\|serine-kinase	gnl\|CDD\|238899	cd01918, HprK_C, HprK/P, the bifunctional histidine-containing protein kinase/phosphatase, controls the phosphorylation state of the phosphocarrier protein HPr and regulates the utilization of carbon sources by gram-positive bacteria. It catalyzes both the ATP-dependent phosphorylation of Ser-46 of HPr and its dephosphorylation by phosphorolysis. The latter reaction uses inorganic phosphate as substrate and produces pyrophosphate. Phosphoenolpyruvate carboxykinase (PEPCK) and the C-terminal catalytic domain of HprK/P are structurally similar with conserved active site residues suggesting these two phosphotransferases have related functions. The HprK/P N-terminal domain is structurally similar to the N-terminal domains of the MurE and MurF amino acid ligases.	4.19274e-26

>NC_010511.1|WP_012330226.1|287692_288460_+|SDR-family-oxidoreductase
MPLFDLTGRVAVVTGSSRGIGRAIAERLAEHGARVVVSSRKEEACRAVAEAINARHGEERAVVVPANISSKADLERLARRTEERFGRIDVLVCNAASNPYYGPMSGISDEAFRKILDNNVVANHWLIGFCAPGMIARRDGAIIIVSSVGGLKGSGVIGAYNVSKAADFQLARNLAVELGPHNVRVNCLAPGLIQTDFARALWEDPASRAAYTARTPLGRIGQPDEIAGAAVFLASPAGAFMTGQSIVIDGGQTIT
>NC_010511.1|WP_012330225.1|286261_287464_-|acetyl-CoA-C-acyltransferase
MREAVIVATARTPIGKAYRGAFNDTQAQALGGHAIAAAVARAGIDPAEVGDVVMGAALQQGSTGSNIARQAALRAGLPASVAGMSLDRQCASGLMAIATAAKEIVADGVDVAVGGGLESISLVQNDRINRFRGTDPWLVERVPALYMTMIETAETVAERYGIDRAAQDAYALQSQRRTAEAQAAGRFADEIVPLATRMTVTDKATGETASREVTLAQDEGNRPQTRPEDLAALKPVFKDGQRVKEGRFVTAGNASQLSDGASASVLMEAREAERRGLQPLGAYRGMAVAGCNPDEMGIGPVFAVPKLLRQHGLSVEDIDLWELNEAFACQVLYCRDRLGIPDERLNVNGGAISIGHPYGMSGARMTGHILLEGRRRGAKYGVVTMCVGGGMGAAGLFEIY
>NC_010511.1|WP_012330224.1|284087_286163_-|3-hydroxyacyl-CoA-dehydrogenase
MTEATPVSESREGAVAVLTLQSGPVNALGTALREGIAAALARAEADTAVTAIVLIGGGRMFSAGADITEFGTPPRGISLPDLLDRIEAATKPVVAAIHGNALGGGLETALACHYRVAVPSAKVGLPEVKLGILPGAGGTQRLPRIVGPRKALEVIVGGAPLGAGQAAAMGLIDELAPEEGLRAHAVAFAQRVVAEGRPLTKIRDRDERLAEGRDAPGLFDAFRKENARRMRGFEAPEACIACVEAACRLPFPQGLAFEREQFLKLVSGSQSAAQRYVFFAERQTAKIPDVPEDTPTRPIARVGVIGAGTMGGGIAMNFLNAGIPVTIVEARREALDRGLAVIRSNYENTARKGRLRPEDVQTRMGLLADTLAIEDLKDCDLIIEAVFEDMGIKKEIFSKLDRVAKPGAILASNTSYLDIDEIASVTGRPADVIGMHFFSPANVMRLLEVVRGARTAKDVIATAMQVGRKVGKIAVLVGVCHGFVGNRMLAERQREANRLILEGVTPWDVDRVIYEFGLPMGPFAMSDLAGLDIGWSRETNRSESVRDLLCEIDRRGQKTGAGFYDYDAKRKASPSPVTEEIIARVAARQGVARKPASDQEILERCLYPMVNEGAKILDEGKAIRASDIDIVWINGYGWPVYRGGPMFWADGIGLPTVLERLRAYQAEYGDAFAPSPLLERLAAEGKGFRDL
>NC_010511.1|WP_012330223.1|282818_284021_-|pimeloyl-CoA-dehydrogenase-large-subunit
MDLRFTPEERAFRQEVRRFFEENLPAEIRQKLIDGHHPSKQDIVTWQRILNAKGWAVPNWPVEWGGTGWDPVRQYIFLDELQSFPAPSPLQFGVYMVGPVIAQFGSEAQKRHFLPRIANLDDWWCQGFSEPGAGSDLASLKTRAVRDGDHYVVNGQKTWTTLAQHADWIFCLVRTDTAAKKQEGITFLLIDMRTPGITVRPIQTLDGGREVNEVFFDDVRVPVENRVGQENRGWDYAKFLLGNERTNIARVGVSKQRIRRLRELAALERVGDAPLIEDPRFREKLAALEIELKALEMTQLRVVAAERTREKGKPDPASSILKIKGSEIQQATTELLLDVVGPYALPYLPEDEDQGHNEPPIGPDYAGPAAPTYFNWRKISIYGGSNEIQKNIIAKAILGL
>NC_010511.1|WP_012330222.1|281529_282678_-|acyl-CoA-dehydrogenase
MDFDLSEEQSLLKDSVERLLADRYDFEARTRHGRHPEGFSPEMWRSYAEQGLLAVPFAEEDGGIGGGPVETMIVMEAFGRALVLEPYLATVVLAGGLMRRAASAAQRAEWLPGLIGGETRYAFAHHERQARYDLHDVGLSARRDGAGYVLEGDKSLVLHGDSADRLIVSARTAGSRRDRGGIGLFLVDARAEGVSRRGYPTQDGQRAAEISLSSVKVGPEAVLGAPEDALPAIERVVEEAIAALCAEAVGAMDRMHALTVEYLKTRKQFGTPIGSFQVLQHRAADMFIALEQARSMAFLATMMAGEEDAAERARALSGAKVQIGRSGRIVGQGAVQLHGGVGVTMEYSVGHFFKRVTMIDTLFGDADHHLARVAAMGGLIAA
>NC_010511.1|WP_043701974.1|280314_281424_-|GTP-binding-protein
MPDPSRRPAPIPLTVLTGFLGAGKTTLLNRLLRDPALADTVVIVNEFGEVGLDHLLIETVDEGMILLGAGCLCCSVRGDLIATLEDLLRKRDNGRIQPFRRVIIETTGLADPAPILHGLLYHPYLALRFALQAVVTVVDAVNGAGTLDAHPEALRQAAVADRLVLTKTDLPGGEAAALRARLAALNPAAPVLGPDAPAEALLGGLFGTDGKIADVAAWLGAEAVAAAEARHHHAQHHGHHHHDLNRHDAAIRAFSLVSPEPVPRAAFEMFLDLLRSGQGAKLLRLKGLVGLAEDPGRPVVVHGVQHVVHAPATLDAWPGPDRTSRLVLILRDGDPAFVRRLWDAFLGRPAPDAPDAAALTANPLAIPGG
>NC_010511.1|WP_012330220.1|279252_280188_-|hypothetical-protein
MTTTPFSVIQGGIREEGRWSAELRHPASLREAEIAAWRALLPRALSPGFAGDPDFVLTLAQHLAEGRRLALLLVWQHGDGMPVLRGVLPLQLPAGLRPGRTAQLWVLPLAEGAAPVVDARETAAILRAALDHLAGAGSRVGTLRLPGLLPAGRLIAALREVAAASGRPLTVASRPAPGPAAEPLPTLPRGRTSLERVRAPRQLRDAVEHFLVLEGARPGPNLLHDADAATALRVVTRRFAQRRACGVDLVRRDGAVVAAAIRLGPAGQDRIWREAGCALAPARERPGVMLLDAAVSVAPARRAADGERRSA
>NC_010511.1|WP_012330219.1|278843_279164_+|HPr-family-phosphocarrier-protein
MNDDDAGGWDAPAVPEGATARELPIINRRGLHARASAKFVQAVERFESEVTVTRAGETVGGRSIMGLLTLGAAQGTSIFVTALGPDQDACLEAIAALLANRFGEDE
>NC_010511.1|WP_012330218.1|278356_278758_+|PTS-sugar-transporter-subunit-IIA
MIGMVLVTHGLLATEFKAALEHVVGPQEQLETITIGPEDDMEVRRKDIMSAVCRVNTGEGVVVLTDMFGGTPSNLALSCMNGGSVEVVAGINLPMLIKLASVRDEESLGEAVLHAQEAGRKYINVASRVLAGK
>NC_010511.1|WP_085984455.1|277805_278267_+|serine-kinase
MSAGPVTLHATCVVLGESGVLIRGPAGSGKTTLARDLLAGGSQCGLHAALVGDDRVIVEACHGRLVARPHPALAGLVEIRGVGLQTLENTLPSAVVRLVLDLAETAPRMPEAGAEKTTLLGVSLPRMILPRDPSRTSTVLWRWRRPRGIMMTE
>NC_010511.1|WP_043701977.1|288684_290403_+|AMP-binding-protein
MPMTESPAWPALSFAEATARLTAPGSPFAVDEAVIRGVPTRIWAAAPPTLRDILLVGRRHGEKTFLVYEDERASFEAFARAVLALSADLIRGGVRPGDRVAIAMRNLPEWPVAFFAALLAGAVAAPLNGWWTGPELAYALADCGASVAVVDAERLARLAERRQDCPDLRRVLLARGEAPDAESLREIIGPVAAWAALPPGTVPDVPLAPDDLATLFYTSGTTGRPKGAMGTHRNGACAVLAHPYSAARAALRRGEPVPVPDPAAPQKVALVSVPFFHVTGCFATLVTNLHRGGRLVLMRRWDLAQALDLIARERCTSAGGVPTIAWQLLDGWAAGTHDLSSLETITYGGAPAPAELVRRLRAAFPRTTPATGWGMTETSATFTHHMGEDYLHRPDSCGPPLPIGEARIVDPEGRVLPPGEVGELQVKGPNVVAGYWNRPDETAASFRDGWLATGDLARMDAEGFLTIVDRARDMLIRGGENIYCCEVENALHEHPAVVDAAVVAVPHPTLGEEPAAVVALARGENASEEELRAFVAARLAAFKVPVRILFHEEILPRNPSGKILKSELRKLF
>NC_010511.1|WP_012330228.1|290488_291031_-|acetolactate-synthase-small-subunit
MNAMNTHYPEPVRVEPVARHTLAVIVDNEPGVLSRIAGLFSGRGYNIESLTVSETEHTQHLSRITIVTTGTNAVIDQIKAQLDRLVPVHRVVDLTLQGESLERELCLVKVVGKGEHRVEAMRLASSFGARTLDATLNSFVFELTGSTDEIERFIRLMSEIGLVEISRTGVAAMSRGAEPM
>NC_010511.1|WP_012330229.1|291049_292828_-|acetolactate-synthase-3-large-subunit
MGAAEVMTGAEMVIRALQDQGVDTLFGYPGGAVLPIYDALFHQDSVKHILVRHEQGAVHAAEGYARSSGKVGCVLVTSGPGATNVVTGLTDALLDSIPLVCITGQVPTHLIGSDAFQECDTVGITRSCTKHNYLVKSIDDLPRILHEAFYVASHGRPGPVVIDLPKDVQFASGLYRRPVENGHKTYKPQIQGDRSKIRAAVALMAGARRPVFYTGGGVINSGPEASRLLRELVRTTGFPITSTLMGLGAYPGSDPQFLGMLGMHGTYEANLAMHECDVMICIGARFDDRITGRLDAFSPFSKKIHVDIDASSINKNVKADLAILGDCASVLADMLAEWRAITPTPDKGRLTEWLSKINGWKARECLGYWPSATTIKPQHAVQRLYEATKHRETYVTTEVGQHQMWAAQYYKFEEPNRWMTSGGLGTMGYGLPAAIGAQLAHPGALVIDIAGEASILMNMQEMSTAVQYRLPVKIFILNNEYMGMVRQWQELLHGSRYSESYSSSLPDFVKLAEAYGAKGIRCERPGDLDAAIQEMLDYDGPVIFDCIVDKTENCFPMIPSGKAHNEMLLSDYLGETGGDLGSVIGEEGKVLV
>NC_010511.1|WP_012330230.1|293179_293671_+|chemotaxis-protein-CheW
MAGAAAFLVVDVAGTGCAVRREAVREVLPLPRLWRPPGVPAALAGFFSLGGAAVPVLDLAVLFGLAGASAGRPMLYRHLLLVGEAAPLALLVDRVDDLVSVEPEAVTPLPQGTALNGCVAGELRCGGRLLHELAVSRILLAEERARLDAQTRLAQERLAEWAA
>NC_010511.1|WP_012330231.1|293658_295116_+|protein-glutamate-methyltransferase
MGRLTPRAPTEDPAFAALKAAIVARTGHHYYADKDDLLWDRLRGRLRAAAAPDAGAYLAHLSASEEEWAALEAEITIGETFFFRYAEQFAALRRTILPERIAARAREKRLRIWSAGCSTGPETYSLAILLHEILGEALAEWRIALTGTDINREVLAVARRAEYGAWALRSLSAEERARYFRRGARENTFALRPEFRGLARFEPQNLLHLVDGTASLALTDYDLILCRNVLIYFHPDTVMAVVRALAERLRPGGWLLLGHAEPNPAFAEILRPVSLPGTAAYRRPEEDPAPLPALPPGPAQESFPPRVPPPAPSRPARRAPARPSPPPAPPASPAGESPPGESPPSESPPSESPPGAALAAVRALADAGDLDASWQACRAALQADPTDARLRFYEGLLARARARPEEAERAFRAAIYLEKGFVMAHYHLGLTLIALGRGAAGRRAVENALRLAAPLPPETELPEGDGLTAARLTDAARPLLDAVAP
>NC_010511.1|WP_083784615.1|295112_295850_+|chemotaxis-protein-CheW
MTGPAHPTAAPGAALGAEATLGAGATLGADAALGADAALGAEAALGAEAALGAEAALGADAALGADAALGAARVEAILDARSRALAERGRAPAETRARRRVLLCRIGTECLALPLDAVAEVAPFRPCTPVPGAPPALIGLSGRGGALLSILDLATALDLPPLPAEAAAHLVVLRRDAPRLGLRVERALAVLDALLDPGPAPPGRAVAGHARAEAADAERFALRESFALLDLAALLQPILGAAPRT
>NC_010511.1|WP_012330232.1|295873_297559_+|methyl-accepting-chemotaxis-protein
MTSVSISIGNRILLGFTAVILVIVALGLYALAQIGDVRRATDLIVSRDLAVMHQLEGIREAQRRMSDLRDEATTRYFLRALNREVPPKEEPAVGWRRAATAAETALASAITNVNEYRGQSLSADRAAAWQRIGEILTAAGVELRAIRTGTERQFQALDAGDVATVQNAETDLDQAQESFGRTMVSARDALDEAIAAGQRRVGAVYEESRISTIAALATCVVMALVITALIRRSVAHPLETVMAFVGRVGEGDLTGRIADRSRDEFGRLGLVLNQMVDGLRELASQNRGATANLNAAAAEIRASAQEQAASVEEQFAAVQETAATVDEITHAGAQIGKRAQEVIATAQATAQTSQAGLRAVDETARAMDAIREQSEAVATNIVSLSEKTQAIGEIIATVNDVSERTHLLALNAAIEAAAAGESGRSFAVVASEMKALADQAKEATGQVRALLGDIQRGINASVMLTEEAVKRVALGKERSDTTHATIEEITARVQESVQTFQQIVASTNQQQLGIEQVMGALQNIRQASQQTAAGTRQVESAAANLSELATALTALAQRYRL
>NC_010511.1|WP_012330233.1|297666_299910_+|hybrid-sensor-histidine-kinase/response-regulator
MDIRAMLLAAFEAEHREHLGAIRAALAAAREGRGPDWNDVFRRAHSLKGAARAVDLPAIEEIAHRLETLFDRIVEGAHPLDAAALAAVTLALDRIEGMAAGLAETPDPPLPADAAAALDRALGLQPPAAPPHREAAPATPPAAPAPQAEPAPEPALSVLRIASDDVEGLSRAVHGLSLALQGHDEIGGALAALDGQGRILRRTADAWRERTGEVAALARRLREAGDPGAALLEAALDLGRRLDGEARVMVRGVSGLARDQHRAAGTVEAAARRLRESSDRLLLVPAETVFGGYGRMVREIAREAGLPVEVRLQGLDVPIDRSLLQELKDPVLHLMRNAVSHGAEPPDERRRKGKPEALTVTLSLAVRGGDLVLAVRDDGRGPDVARIVETARRQGLIAPDARPTTREALGLVFAPGFSTTDKIDRLSGRGVGLSVVAEAAARLRGRARLRRAQPHGAEVVVVVPLSAARRPLLLVEAGGRVYAIPSGAAARLLRLRAAEIAPVAGVPSARLSLDGRDAVVPVVPLAGLLGGDATLPVEDGLLRGVLLRSGSDLCLAAVDRLLDVRASLVGPPPPIGGEAGLFSGTILLTDETPALVLDPAGLLARAGETAGRVAPAPARAEAPGRRWTILVVDDSITTRTLEKSILEAQGYRVFVCVDGQDALERLRRDHAEVDLVVADVEMPRLDGFGLLQAIKADPALTRLPVILMTSRGDPADIRRGLDLGADAYITKQKFDQRELLDTIGQLL
>NC_010511.1|WP_012330234.1|300019_301087_+|chemotaxis-specific-protein-glutamate-methyltransferase-CheB
MTAPVRVMLVEDSLVVRQLLAHIVSRDPRLALVAAVPSGEEALREIHRVQPDVISMDIRLPGIDGLETTRRIMAERPTPIVVIADAVEDSSLKISMNALRAGALSVVEKPVGTGHRAYAAVADEICTQLRIMSEVPVIRRRPIGAERERPPLFDPPARPDAVGAPPGLVAVAASTGGPPAFARLLGALPAAFPAPILLVQHMGAAFMDGFAAWLNGVVPLAVEIAAEGVRPLPGHVYVAPGDRHLEFGPGGLIALSDDPPIGGQRPSATALFRSLARHAGSRALGILLTGMGEDGAAGLLDMRRAGALTIAEHETSAVVYGMPAAAVRLRAASAVLPLDMIAPRILRAVQPGAAR
>NC_010511.1|WP_012330235.1|301083_302805_+|response-regulator
MRAAPTGAAPARILLVEDSETQALQLRLFLEGSGFAVTRCATAEAALDALNQGLPDLVVADYHLPGINGDELTRQMRLSLRTRATPVLMLTEAQGRDLERQGLESGADAYVPKSADRDLLVLRIRALLRERGAGTAQEAGHGAFRRARILVVDASATYRAYLAGLFGQDGHAVVAAEGPDQALAALAAPDAAFDCVTVDLLSTAYEAVELCRRVASLRESAGGPGFYLVGIGSAAAAGKDLLVQAFAAGVDDVVPKGAEGEVLAIRVRTLVRRKLLEEDNRRVADELRQHERAVERAQAEAAAAEAKAALAGALERANRDLADANRQLKDAQAKLVQAAKMASLGELVAGIAHEINNPLAFILAHQGTVERLVGEVAEQAEGLPEPARRALAKARDRIGAMRLGLGRIQDLVVNLRKFSRLDEGEMRSVNVPDAIETVLALLQHKLGTRIAVERLFAGEPEIRCTPALLNQVVMNIIGNAADAIPGEGRITVETLSEAENDVIRISDTGPGVPEALRERIFEPFFTTKPVGSGTGLGLAIAYSVVQAHSGTISVETAPGGGACFVISIPRRPA

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Crispr_ID: NC_010511_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_010511_2

352304-352392

Orphan

Consensus_repeat	Method
TGGGCTTCGCTCAGGCGCCGCGCGGGC	CRISPRCasFinder

1 spacers

The CRISPR arrays of NC_010511_2

>merge|NC_010511|2|352304-352392|CRISPRCasFinder
TGGGCTTCGCTCAGGCGCCGCGCGGGCTCATGATCCGCTCGATCCCTTCGGGATGGCGGATCTGGGCTTCGCTCAGGCGCCGCGCGGGC

>NC_010511|2|2|352304-352392|CRISPRCasFinder
TGGGCTTCGCTCAGGCGCCGCGCGGGC	TCATGATCCGCTCGATCCCTTCGGGATGGCGGATC
TGGGCTTCGCTCAGGCGCCGCGCGGGC

Protein	Signature genes	Signature genes Name	Protein_function
NC_010511.1\|WP_012330281.1\|357816_358410_+\|aldehyde-dehydrogenase-iron-sulfur-subunit	unknown	unknown	gnl\|CDD\|236910
NC_010511.1\|WP_012330276.1\|351193_351463_+\|cell-division-topological-specificity-factor-MinE	unknown	unknown	gnl\|CDD\|234718
NC_010511.1\|WP_012330280.1\|356327_357419_+\|recombinase-RecA	unknown	unknown	gnl\|CDD\|236476
NC_010511.1\|WP_012330277.1\|351522_352113_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|227505
NC_010511.1\|WP_012330269.1\|344175_344682_+\|peptidoglycan-associated-lipoprotein-Pal	unknown	unknown	gnl\|CDD\|274307
NC_010511.1\|WP_012330279.1\|353854_356185_+\|peptidase-C14	unknown	unknown	gnl\|CDD\|226700
NC_010511.1\|WP_012330270.1\|344789_345731_+\|tol-pal-system-protein-YbgF	unknown	unknown	gnl\|CDD\|188247
NC_010511.1\|WP_012330284.1\|362108_365852_-\|vitamin-B12-dependent-ribonucleotide-reductase	unknown	unknown	gnl\|CDD\|236049
NC_010511.1\|WP_012330278.1\|352424_353675_-\|nucleoside-transporter	unknown	unknown	gnl\|CDD\|224883
NC_010511.1\|WP_012330275.1\|350381_351197_+\|septum-site-determining-protein-MinD	unknown	unknown	gnl\|CDD\|225447
NC_010511.1\|WP_012330283.1\|359360_361580_+\|xanthine-dehydrogenase-family-protein-molybdopterin-binding-subunit	unknown	unknown	gnl\|CDD\|224446
NC_010511.1\|WP_043701983.1\|366474_366885_+\|NADH:ubiquinone-oxidoreductase-subunit-NDUFA12	unknown	unknown	gnl\|CDD\|236176
NC_010511.1\|WP_012330282.1\|358406_359357_+\|xanthine-dehydrogenase-family-protein-subunit-M	unknown	unknown	gnl\|CDD\|224238
NC_010511.1\|WP_012330268.1\|343390_343786_-\|response-regulator	unknown	unknown	gnl\|CDD\|381085
NC_010511.1\|WP_012330273.1\|348904_349081_-\|hypothetical-protein	unknown	unknown	unknown
NC_010511.1\|WP_012330287.1\|367639_368689_-\|response-regulator	unknown	unknown	gnl\|CDD\|226434
NC_010511.1\|WP_012330286.1\|366946_367579_+\|DUF2155-domain-containing-protein	unknown	unknown	gnl\|CDD\|227106
NC_010511.1\|WP_150108561.1\|349541_350261_+\|septum-site-determining-protein-MinC	unknown	unknown	gnl\|CDD\|235357
NC_010511.1\|WP_012330272.1\|346885_348808_+\|ATP-dependent-metallopeptidase-FtsH/Yme1/Tma-family-protein	unknown	unknown	gnl\|CDD\|223541
NC_010511.1\|WP_012330271.1\|345727_346762_+\|tRNA-lysidine(34)-synthetase-TilS	unknown	unknown	gnl\|CDD\|238950

Protein	Function_ID	Function_description	E-value
NC_010511.1\|WP_012330281.1\|357816_358410_+\|aldehyde-dehydrogenase-iron-sulfur-subunit	gnl\|CDD\|236910	PRK11433, PRK11433, aldehyde oxidoreductase 2Fe-2S subunit; Provisional.	8.20992e-122
NC_010511.1\|WP_012330276.1\|351193_351463_+\|cell-division-topological-specificity-factor-MinE	gnl\|CDD\|234718	PRK00296, minE, cell division topological specificity factor MinE; Reviewed.	2.6975e-21
NC_010511.1\|WP_012330280.1\|356327_357419_+\|recombinase-RecA	gnl\|CDD\|236476	PRK09354, recA, recombinase A; Provisional.	0
NC_010511.1\|WP_012330277.1\|351522_352113_+\|hypothetical-protein	gnl\|CDD\|227505	COG5178, PRP8, U5 snRNP spliceosome subunit [RNA processing and modification].	2.22028e-05
NC_010511.1\|WP_012330269.1\|344175_344682_+\|peptidoglycan-associated-lipoprotein-Pal	gnl\|CDD\|274307	TIGR02802, Peptidoglycan-associated_lipoprotein, peptidoglycan-associated lipoprotein. Members of this protein are Pal (also called OprL), the Peptidoglycan-Associated Lipoprotein of the Tol-Pal system. The system appears to be involved both in the maintenance of outer membrane integrity and in the import of certain organic molecules as nutrients. Members of this family contain a hydrodrophobic lipoprotein signal sequence, a conserved N-terminal cleavage and modification site, a poorly conserved low-complexity region, together comprising about 65 amino acids, and a well-conserved C-terminal domain. The seed alignment for this model includes only the conserved C-terminal domain.	3.49306e-53
NC_010511.1\|WP_012330279.1\|353854_356185_+\|peptidase-C14	gnl\|CDD\|226700	COG4249, COG4249, Uncharacterized protein containing caspase domain [General function prediction only].	3.94955e-43
NC_010511.1\|WP_012330270.1\|344789_345731_+\|tol-pal-system-protein-YbgF	gnl\|CDD\|188247	TIGR02795, Uncharacterized_protein_in_oprL_3'region, tol-pal system protein YbgF. Members of this protein family are the product of one of seven genes regularly clustered in operons to encode the proteins of the tol-pal system, which is critical for maintaining the integrity of the bacterial outer membrane. The gene for this periplasmic protein has been designated orf2 and ybgF. All members of the seed alignment were from unique tol-pal gene regions from completed bacterial genomes. The architecture of this protein is a signal sequence, a low-complexity region usually rich in Asn and Gln, a well-conserved region with tandem repeats that resemble the tetratricopeptide (TPR) repeat, involved in protein-protein interaction.	1.40091e-29
NC_010511.1\|WP_012330284.1\|362108_365852_-\|vitamin-B12-dependent-ribonucleotide-reductase	gnl\|CDD\|236049	PRK07562, PRK07562, vitamin B12-dependent ribonucleotide reductase.	0
NC_010511.1\|WP_012330278.1\|352424_353675_-\|nucleoside-transporter	gnl\|CDD\|224883	COG1972, NupC, Nucleoside permease [Nucleotide transport and metabolism].	1.04228e-140
NC_010511.1\|WP_012330275.1\|350381_351197_+\|septum-site-determining-protein-MinD	gnl\|CDD\|225447	COG2894, MinD, Septum formation inhibitor-activating ATPase [Cell division and chromosome partitioning].	4.34793e-154
NC_010511.1\|WP_012330283.1\|359360_361580_+\|xanthine-dehydrogenase-family-protein-molybdopterin-binding-subunit	gnl\|CDD\|224446	COG1529, CoxL, Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL/CutL homologs [Energy production and conversion].	0
NC_010511.1\|WP_043701983.1\|366474_366885_+\|NADH:ubiquinone-oxidoreductase-subunit-NDUFA12	gnl\|CDD\|236176	PRK08183, PRK08183, NADH:ubiquinone oxidoreductase subunit NDUFA12.	1.89589e-67
NC_010511.1\|WP_012330282.1\|358406_359357_+\|xanthine-dehydrogenase-family-protein-subunit-M	gnl\|CDD\|224238	COG1319, CoxM, Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM/CutM homologs [Energy production and conversion].	1.03046e-80
NC_010511.1\|WP_012330268.1\|343390_343786_-\|response-regulator	gnl\|CDD\|381085	cd00156, REC, phosphoacceptor receiver (REC) domain of response regulators (RRs) and pseudo response regulators (PRRs). Two-component systems (TCSs) involving a sensor and a response regulator are used by bacteria to adapt to changing environments. Processes regulated by two-component systems in bacteria include sporulation, pathogenicity, virulence, chemotaxis, and membrane transport. Response regulators (RRs) share the common phosphoacceptor REC domain and different effector/output domains such as DNA, RNA, ligand-binding, protein-binding, or enzymatic domains. Response regulators regulate transcription, post-transcription or post-translation, or have functions such as methylesterases, adenylate or diguanylate cyclase, c-di-GMP-specific phosphodiesterases, histidine kinases, serine/threonine protein kinases, and protein phosphatases, depending on their output domains. The function of some output domains are still unknown. TCSs are found in all three domains of life - bacteria, archaea, and eukaryotes, however, the presence and abundance of particular RRs vary between the lineages. Archaea encode very few RRs with DNA-binding output domains; most are stand-alone REC domains. Among eukaryotes, TCSs are found primarily in protozoa, fungi, algae, and green plants. REC domains function as phosphorylation-mediated switches within RRs, but some also transfer phosphoryl groups in multistep phosphorelays.	1.57049e-13
NC_010511.1\|WP_012330287.1\|367639_368689_-\|response-regulator	gnl\|CDD\|226434	COG3920, COG3920, Signal transduction histidine kinase [Signal transduction mechanisms].	2.94395e-51
NC_010511.1\|WP_012330286.1\|366946_367579_+\|DUF2155-domain-containing-protein	gnl\|CDD\|227106	COG4765, COG4765, Uncharacterized protein conserved in bacteria [Function unknown].	1.20364e-51
NC_010511.1\|WP_150108561.1\|349541_350261_+\|septum-site-determining-protein-MinC	gnl\|CDD\|235357	PRK05177, minC, septum formation inhibitor MinC.	1.44326e-103
NC_010511.1\|WP_012330272.1\|346885_348808_+\|ATP-dependent-metallopeptidase-FtsH/Yme1/Tma-family-protein	gnl\|CDD\|223541	COG0465, HflB, ATP-dependent Zn proteases [Posttranslational modification, protein turnover, chaperones].	0
NC_010511.1\|WP_012330271.1\|345727_346762_+\|tRNA-lysidine(34)-synthetase-TilS	gnl\|CDD\|238950	cd01992, PP-ATPase, N-terminal domain of predicted ATPase of the PP-loop faimly implicated in cell cycle control [Cell division and chromosome partitioning]. This is a subfamily of Adenine nucleotide alpha hydrolases superfamily.Adeninosine nucleotide alpha hydrolases superfamily includes N type ATP PPases and ATP sulphurylases. It forms a apha/beta/apha fold which binds to Adenosine group. This domain has a strongly conserved motif SGGXD at the N terminus.	2.71712e-60

>NC_010511.1|WP_012330277.1|351522_352113_+|hypothetical-protein
MATDVPTIYANAVLGLSLRRPGILQLTLGAAGFAAEEADAVVRLALPDDTVVELVDALVEGLQAAAESDEEDEEGPEPYEASVGDVATAGLLATTLATAMGDALSLLSERPDFAERLNEIEERALLTTRNSVSEGVSVEDEAKAVRDTVAVLQSLFAHWRSEHGPPSDPPPPETPPPDSPPEAPPPGTPPEPGPTG
>NC_010511.1|WP_012330276.1|351193_351463_+|cell-division-topological-specificity-factor-MinE
MKPFGFRSRRGSALAARDRLKILLAQDRALFGRRDLITLLREEVILAIAKHVAIDVDKVRVNLDRRGGIATLGIDIDLPAHKGASLAGA
>NC_010511.1|WP_012330275.1|350381_351197_+|septum-site-determining-protein-MinD
MAKVLVVTSGKGGVGKTTTTAALGAALAQMGENVCVVDFDVGLRNLDLVMGAERRVVYDLINVVQGDAKLAQALIRDKRLDTLSLLPASQTRDKDALTEEGVARVVTELRERFDWVICDSPAGIERGATLAMRHADVAVVVTNPEVSSVRDSDRIIGLLDSKTVRAEAGESIDKHLILTRYEPARADKGEMLRIEDVLEILSIPLLAVVPESEEVLKASNVGSPVTLHNPASAPSRAYVDAVRRLRGETVAMTIPTERRSLLNRLIPRRAA
>NC_010511.1|WP_150108561.1|349541_350261_+|septum-site-determining-protein-MinC
MVAGNKASMTVTSTRHTRPSLPLRGRAFRALVLAPERPLDAWFAQLDALVLRSPTLFAERAVILDAAGLAPEAEESAPDLAHLLAELGRRGIRILGIERAEATWTDAAMPPRLAGGRPAPITPPIADKPKLNSCVLETSLRSGQSIFHPDGDVTVMGSVSSGAEILAGGSIHVYGALRGRAIAGAGGNRRARIYCRKFQPELLGIDGLFRTAETTDPGLHNKAVQVWLERDALRMAALD
>NC_010511.1|WP_012330273.1|348904_349081_-|hypothetical-protein
MRKILTLSAVLMFVAGPVLAQGRPAGSSAGAAENATQNNKPVSGTAGGGGGGAGGGGK
>NC_010511.1|WP_012330272.1|346885_348808_+|ATP-dependent-metallopeptidase-FtsH/Yme1/Tma-family-protein
MNPNFRNFALWVVIFLLVLALVTLFQNPGHRSGGSEIAYSQLLNDADAGRIQSVVISGQEVSGSYTGGGTFTTYAPNDPSLVSKLQSKGVTITARPPSDNTPWFIALLVNWLPILVFIGAWIFLSRQMQSGAGRAMGFGKSKAKLLTEAHGRVTFEDVAGVDEAKEDLQEIVEFLRDPQKFQRLGGRIPRGVLLVGPPGTGKTLIARAVAGEANVPFFTISGSDFVEMFVGVGASRVRDMFDQAKKNAPCIIFIDEIDAVGRHRGAGLGGGNDEREQTLNQLLVEMDGFEANEGIIIIAATNRPDVLDPALLRPGRFDRQIIVPNPDVIGRERILRVHVRKVPLAPDVDLKVIARGTPGFSGADLMNLVNEAALLAARRGKRIVTMHEFEDSKDKVMMGAERRTLVMTDDEKRLTAYHEGGHAIVALNVPATDPVHKATIIPRGRALGMVMQLPERDKLSMSFEQMTSRLAIMMGGRVAEEMIFGPEKVTSGAQSDIEQATRLARMMVTRWGFSPELGTVAYGENNDEVFLGMQVNRQQNVSEATAQKIDAEVRRLVESGLQDARRILSDHRNDLEALARGLLEYETLSGEEIRDLLDGKPPVRDTGDYPPAPARGSPVPSAGRGRPRESDGGYEPQPQA
>NC_010511.1|WP_012330271.1|345727_346762_+|tRNA-lysidine(34)-synthetase-TilS
MSDAARPLDPDEAARRLGPWLGAGGQAGGVVLAVSGGPDSTALMGCAAALPPRVPVLVATVDHGLRPESGEEAAGVAALAGRLGLPHRILTWRGEKPRTRLQEAARAARYDLLLGLAREAGAGAILTAHTLDDQAETVLMRLCAGSGPAGLAGIAPARRLGGLLLGRPFLDLPKARLVATCAAAGWPFAVDPGNAAARFARARLRRVMPLLAAEGLTPARLARLAARLRRNEAALAAAAEAARPSLAAAPAGPGRLALDAAGLAALPEAVALRVLADAIAALRAGERRPERLERLEEALFGRILPAIAAGTPLRLTLGGALLDLAGGRLLLAPEPPRRRTKRAG
>NC_010511.1|WP_012330270.1|344789_345731_+|tol-pal-system-protein-YbgF
MLRRLILATGLLLAASLPGRAQDAADLVVRLNRLENQSRQMAGQIETLQYENRQLKEQLRKFQEDVEFRFQEGKGGRTAAPAGKPQKRGDAFDPTTSPGAPGAPRALGAAPGAAPALATATPSAPRAAAAAPATPNTTATLSPPPAAIEEDQVPSYGEPVDLAPSARAPAPPARPRESVAATATGDAKADYEAAYAYVLQRQYEQAEMRLRQFIQSHPRDALVPDATYWLGETYLQRNRTREAAEQFLKVSTDYARSRKAPEAMLKLGASLNALGAREQACATLAELERKFPQAPASVRQGVDREQKRARCAA
>NC_010511.1|WP_012330269.1|344175_344682_+|peptidoglycan-associated-lipoprotein-Pal
MSLPLAPSRVLRAAAALAFALSIAACSSNKDLADASAYAAGGAATPGSAQDFVVNVGDRVFFETDSTDLTATATATLDKQAQWLSRYPRYTFLIEGHADERGTREYNFSLGARRSQAVRDYLTSRGIAASRMRTVSYGKERPVAVCNDISCWSQNRRAVTVLDGGAGS
>NC_010511.1|WP_012330268.1|343390_343786_-|response-regulator
MAATSLRPTSVLVVEDNYLLLELIVALLAQEGLTAHAASSGEAALTLLRRHGPAVDWLFTDIVLPGLIDGWMVAEAYRALHATRPVVFASTTVHLDPRRARGGIVLQKPFALDDVVGVARMMRGEVGQRCA
>NC_010511.1|WP_012330278.1|352424_353675_-|nucleoside-transporter
MAERILHAALSLAVLLAIAVLASTDRRAIRPRTVLSALAIQVLLGAAILLLPTGRRLLGTAAEAVAAVLAYGDRGAAFLFGGLVAPRMFDLFDQGGFVLAFRVLPQIVYVSALIGVLYHLGIMQGMARVIGAALQRLLGTSRIETFSAVITIAIGQSEIAVALRPFLPLLTGSELFAVMSSGAASTAGSILAGYAALGVPMEYLLAASVMAIPGGLLYAKILVPSTEPSRVRTMRAEFGERRAVNLIEAAAEGTQKGLAVAVAVGAMLIAFVGLIALANGLVGWLGGLLGVAGASIEAILGALFRPLAWILGVPWERAGIVGTAIGQKVAFNEFLAYANLSPVLRSGELGRRTTAILCFALCGFANLASIAIQLASFGSLVPERRAEVASYGLRAILAGSLSNFTSAAIAGLFVEE
>NC_010511.1|WP_012330279.1|353854_356185_+|peptidase-C14
MPQAARRLIGFVVALAALVLPLAGLRAAPAETRIALVIGNGAYPAGALATAANDAGLVAQTLQAAGFDVVGARDLDEDGLRRALRDFTDRAAAAGPEAVAFVYLAGYGLQVEGENYFVPVDARIGAASDVPLRALRVSDYAKRLAALPLRARFLVLDAGRRAPFRVAGEPLAGGLALVEAEPDSLVAFNAAPGTVAPEEPGPYGAYAQALAEMMREGGLAPAELFARVRLRVSETTRGAAVPWHSARIGAPFVFFERGAEAPPLPALAGTDRRPLGEIGPRDAFARCLEQDSLQAYEAFLAAYPQDPLAKRVRAILAARREALTWRRSRVADTPNAYWSYLDRYPRGPHAPDARRRLRQLAAAAEPPDHFAALAYDVPPPPPEERIYVERPVVVLDGPADDLPPPPVLLPPRPAALLDLPPPVVEEYVLPAPVFVPVPAAVRLPATVAPPEGNPLAGRIHERPGPTGSAIAAGVAGAAIGAAVAARVALPPSLSQKAALRPGLPPGAMPAGGLPGQPRGPVPPQAGRPGPPAAIGQPLPGQPLPGQPGRTAPLPAQARPGPPPIPGQALPGPAAPANRPGAGAAPTLRAQPAPGAPPRAAPPAAPVQALRPGWPPPGQPPAGRPASPHGPVAAPAPNPDFARQQQVRQEQAAQAQAAQARAAQARAAQAQRAAAAQRQQMMMQQRQQEAARAFQQRQQVMQQQASQAAARQQAAQAAARQQQMMMQQQAAAQRQHQMQMMQMQRPPPAAPRAVPQPAPHPGHGGRPCGQPGLPPCR
>NC_010511.1|WP_012330280.1|356327_357419_+|recombinase-RecA
MAQSSLRLVENPTMDKDKSKAIDAALAQIERAFGKGSIMRLGKGDKVQEVETISTGSLGLDVALGVGGLPRGRVIEIYGPESSGKTTLALHTIAEAQKKGGVCAFVDAEHALDPVYARKLGVNLDDLLISQPDTGEQALEITDTLVRSGAIDVLVVDSVAALTPRAEIEGEMGDQQPGLQARLMSQALRKLTGSISRSNCMVIFINQIRMKIGVMYGSPETTTGGNALKFYASVRLDIRRVSTLKDRDEPIGNSVRVKVVKNKVAPPFKQVEFDIMFGEGVSKVGELIDLGVKAGIVEKSGAWFSYDSQRLGQGRENAKGFLRDNPDIAGRIEAAIRQNMGLVADKILENAVPTAEDFDEGEA
>NC_010511.1|WP_012330281.1|357816_358410_+|aldehyde-dehydrogenase-iron-sulfur-subunit
MVGASATTAPAAVPAAAGAQPAGPAAPVTARVAFTVNGARRELDLDLRTSLLDALREHLHLTGTKKGCDHGQCGACTIIVDGRRINACLTLAVMHQGSAITTIEGLGGPESLHPMQAAFVRHDGYQCGYCTPGQICSAVAVLDEIAAGIPSHATADLTAAPDLSEAEIRERMSGNLCRCGAYSNIVEAVTEVAGRRA
>NC_010511.1|WP_012330282.1|358406_359357_+|xanthine-dehydrogenase-family-protein-subunit-M
MKSFTYERPASPAEAASAVARNPGAKFIAGGTNLLDLMKLQIETPAHLVDVNGLGLDAIEATPEGGLRIGALVRNTDLAADPRVRRDYPVLSRALLAGATGQLRNQATTAGNLLQRTRCPYFYDTAQACNKRRPGSGCAALDGISRQLAVIGGSEACIATHPGDMAVAMRVLDAAVETVDATGAARTIPIAEFHRLPGDAPERDTTLRPDELITAVTLPRPLGGAQIYRKVRDRASYAFALVSVAAVVQPDGSGRVAFGGLAHKPWRVEAAEAELPRGAAAVAAGMLSGARPTRDNAFKLRLAERTLGAALKQARA
>NC_010511.1|WP_012330283.1|359360_361580_+|xanthine-dehydrogenase-family-protein-molybdopterin-binding-subunit
MKFDTPAGQNPIDQLKVVGRPTDRIDGKFKTTGTAPYAYERHDVAPNQAYGYVVGAGIAKGRVRAIETEEAARAPGVLAIVTTLDTPRLPRGTMNAAYLFGGDAIQHYHQAVALVVAETFEQARAAAFLIRVDCAPEPGRFDLRAEAGAAKPVPGDSGEGSSGAGEERVGDFEGAFAQAPVTLDATYTTADESHAMMEPHASVAAWEGDRLTLWTSNQMIGWGKGSIAKIFGIPKANVRLDSPYVGGGFGGKLFVRADAVLAALGARAAGRPVKVALTRPMIPNNTTHRPATIQRIRLGATRDGILTAIAHESISGNLPDGDPETAVSQTKLLYAGANRLTALKLAHLDLPEGNAMRAPGEAPGMLALEVAMDEMAEKLGLDPVEFRLRNDTQVDPNQPGRAFSHRDFVGCLRLGAERFGWARRSPTPGQVRDGAWRVGLGMASAFRNNLVLKSGARVRLDGRGRVTVETDMTDIGTGSYTIIAQTAAEMMGLPLDRVEVRLGDSDFPTAAGSGGQFGANSSTAGVYAACVKLREAVAQRLGINSADAVFADGQVRAGNRAVPLGEAAAQGEIVAEDAIEFGGLDKTYQQSTFGAHFVEVGVDADTAEVRVRRMLAVCAAGRILNPKSARSQVIGGMTMGVGAALMEKLAVDTRRGFFVNHDLAGYEVPVHADIPHQEVIFLDEVDAMSSPMKAKGVGELGLCGVGAAVANAVYNATGVRVRDYPLTVDKLIDRMPEAA
>NC_010511.1|WP_012330284.1|362108_365852_-|vitamin-B12-dependent-ribonucleotide-reductase
MRIERRITTAGQSPYAGIPFRKAVSEIRNPDGSVVFRLDGIDVPEAWSQVACDVLAQKYFRKAGVPAALRRVEENDVPSFLWRSVPDEEALAALPEEARYGSETSAVQVFDRLAGCWTYWGWKGGYFSSEEDAAAFLDELRAMLARQMVAPNSPQWFNTGLHWAYGIDGPSQGHYYVDYRTGALTKSASAYEHPQPHACFIQSVQDDLVNEGGIMDLWVREARLFKYGSGTGSNFSALRGENEKLAGGGRSSGLMSFLKIGDRAAGAIKSGGTTRRAAKMVIVDIDHPDIEAFIDWKVREEQKVAALVTGSKVAAKHLKAVMRACLNCEAEGDACFDPERNPALKREVKAARRAMVPDASVKRVIQSARQGATEVDFPIFDTDWDSEAYLTVSGQNSNNSVSLTDDFLRAVEADADWPLRTRIGGKVAKTLKARDLWEKIGAAAWASADPGLHFNTTMNDWHTCPVGGRIRASNPCSEYMFLDDTACNLASANLLALFDRGTRTFDVEAYEHLCRLWTIVLEISVTMAQFPSREIADLSYKYRTLGLGYANVGGLLMTMGLPYDSREGRALAGALTAIMTGVAYATSAEMARELGPFPAYEENADAMLRVIRNHRRAAHGEAEGYEFLSTKPVPLDHAACPQPDLVAHATRAWDRALVLGEEHGYRNAQATVIAPTGTIGLVMDCDTTGIEPDFALVKFKKLAGGGYFKIINRAVPDALRALGYRESEIAEIEAYAVGHGSLGQAPAVNPAALRAKGFTDDKIAAVEAGLKSAFDIKFVFNRWTLGEDFLTRTLRVPAERLADPSFDLLTHLGFTRREIEAANIHVCGAMTLEGAPHLKREHYAVFDCANPCGRTGKRYLSVESHIRMMAAAQPFISGAISKTINMPNDATVEDCKEAYRLSWTLGLKANALYRDGSKLSQPLNAALIADDDEDEAEEAVEALIAQPAAARAAAVAEKIVERVIERVERIRSREKMPDRRKGYTQKAVVGGHKVYLRTGEYDDGRLGEIFIDMHKEGAAFRSLMNNFAIAISLGLQYGVPLEEYVDAFTFTRFEPAGFVQGNDAIKNATSILDYVFRELAISYLGRTDLAHVDPSEIGSTVMGGGVAQSKQPAPEPVVAHTIVSRGLLRGSADRLTLIHGGPGGSTAGVAAPATGLSAPAGGSIHAVRGAVALRTEPALAGRIDALAEALPFGRPEPKAERSVADRRAEAKMKGYVGEACPECANFTLVRNGTCLKCDTCGSTTGCS
>NC_010511.1|WP_043701983.1|366474_366885_+|NADH:ubiquinone-oxidoreductase-subunit-NDUFA12
MKDTLLRIFTWWSGSTVSLEFYTKRHGELVGTDEFGNRYYRAEGPLIDPSVGPERRWVIYNGEADASKVPPGWRGWLSHTVDVAPSEESYTPREWQKPFEPNLTGTVAAYRPRGSQLSYGQRPAATGDYVPWTPGE
>NC_010511.1|WP_012330286.1|366946_367579_+|DUF2155-domain-containing-protein
MSRTTARSAIRAALVLSLAGVLAPAAQADKIRNPTAVFSGLDKITGRIVTFEVSVDETVQFGALQLTPRVCYTRPPTESARTTAFLEVDEVTLENKYRRIFTGWMFAASPGLHAIEHPIYDVWLVDCKGGTDIIAEAKEQDDAPVAAAKPERRRRDPNQQQEARRAQPVNRQGQVDVAPLRGTPVQPRQTPSRRFFPTNDAPSFFNSDPR
>NC_010511.1|WP_012330287.1|367639_368689_-|response-regulator
MSDAAAPGQARILYIDDDPGLGRLVQRALRGRGYAVDLAEDGEAGLARLRAGGIDVVALDHHMPGRSGLEVLAAIRALPEAPPVVYVTGSEDSRVAVAALKAGAVDYVWKDVQGHFRELLGEAIDTALRQEALRRDKERAEAEVRAARDRAEILLREVNHRVANSLALVAALARMQTNAVTDPAAKSALEEMQARISAIAGIHRRLYTSQDVQAVEVDAYLASLVEELEASMKAAGRDHAIRLRAEPIRLATDKAVSLGVVVTELVTNAYKYAYPPEVAGEIRVAITRRGEDALCLVVEDDGIGWSGEGTPLGSGLGSRILRAMGTNLRSKVEYDRLPRGTRATLAFQG

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Crispr_ID: NC_010511_3

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_010511_3

494437-494544

Orphan

Consensus_repeat	Method
CGGCTTCCGCCGGGGCGCTCGGCTCT	CRISPRCasFinder

1 spacers

The CRISPR arrays of NC_010511_3

>merge|NC_010511|3|494437-494544|CRISPRCasFinder
CGGCCTCCGCCGGGGCGCTCCGCTCTTGCGTGAATACGCCCCGGCTTCCGCCGGGGCGCTCGGCTCTGACGTCAAAACGCCCCGGCCTCCGCCGGGGCGCTCGGCTCT

>NC_010511|3|3|494437-494544|CRISPRCasFinder
CGGCCTCCGCCGGGGCGCTCCGCTCT	TGCGTGAATACGCCCCGGCTTCCGCCGGGGCGCTCGGCTCTGACGTCAAAACGCCC
CGGCCTCCGCCGGGGCGCTCGGCTCT

Protein	Signature genes	Signature genes Name	Protein_function
NC_010511.1\|WP_018262812.1\|489802_491935_+\|penicillin-binding-protein-1C	unknown	unknown	gnl\|CDD\|227289
NC_010511.1\|WP_012330390.1\|488741_489728_+\|aldo/keto-reductase	unknown	unknown	gnl\|CDD\|381302
NC_010511.1\|WP_012330401.1\|501004_501514_-\|pyridoxamine-5'-phosphate-oxidase-family-protein	unknown	unknown	gnl\|CDD\|379804
NC_010511.1\|WP_012330393.1\|493090_493315_-\|hypothetical-protein	unknown	unknown	unknown
NC_010511.1\|WP_012330398.1\|496465_497254_-\|histidinol-phosphatase	unknown	unknown	gnl\|CDD\|238819
NC_010511.1\|WP_012330387.1\|480795_482259_-\|peptidoglycan-binding-protein	unknown	unknown	gnl\|CDD\|237030
NC_010511.1\|WP_012330400.1\|499559_500852_-\|nicotinate-phosphoribosyltransferase	unknown	unknown	gnl\|CDD\|235406
NC_010511.1\|WP_012330405.1\|504815_505502_-\|phosphoribosylformylglycinamidine-synthase-subunit-PurQ	unknown	unknown	gnl\|CDD\|235140
NC_010511.1\|WP_012330388.1\|482430_487728_+\|alpha-2-macroglobulin-family-protein	unknown	unknown	gnl\|CDD\|225248
NC_010511.1\|WP_012330392.1\|492071_493007_-\|hydroxymethylbilane-synthase	unknown	unknown	gnl\|CDD\|234612
NC_010511.1\|WP_012330397.1\|495303_496305_+\|alpha/beta-hydrolase	unknown	unknown	gnl\|CDD\|225176
NC_010511.1\|WP_012330386.1\|479852_480677_+\|alpha/beta-hydrolase	unknown	unknown	gnl\|CDD\|223730
NC_010511.1\|WP_012330389.1\|487749_488646_-\|LysR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|176163
NC_010511.1\|WP_012330402.1\|501687_501897_+\|TOBE-domain-containing-protein	unknown	unknown	gnl\|CDD\|226113
NC_010511.1\|WP_012330395.1\|493964_494390_+\|hypothetical-protein	unknown	unknown	unknown
NC_010511.1\|WP_012330403.1\|501902_502943_+\|iron-ABC-transporter-substrate-binding-protein	unknown	unknown	gnl\|CDD\|238567
NC_010511.1\|WP_012330396.1\|494604_495072_-\|Hsp20-family-protein	unknown	unknown	gnl\|CDD\|182691
NC_010511.1\|WP_012330394.1\|493358_493658_-\|antibiotic-biosynthesis-monooxygenase	unknown	unknown	gnl\|CDD\|367760
NC_010511.1\|WP_012330399.1\|497351_499391_-\|AI-2E-family-transporter	unknown	unknown	gnl\|CDD\|223701
NC_010511.1\|WP_012330404.1\|502939_503992_+\|iron-ABC-transporter-permease	unknown	unknown	gnl\|CDD\|223682

Protein	Function_ID	Function_description	E-value
NC_010511.1\|WP_018262812.1\|489802_491935_+\|penicillin-binding-protein-1C	gnl\|CDD\|227289	COG4953, PbpC, Membrane carboxypeptidase/penicillin-binding protein PbpC [Cell envelope biogenesis, outer membrane].	0
NC_010511.1\|WP_012330390.1\|488741_489728_+\|aldo/keto-reductase	gnl\|CDD\|381302	cd19076, AKR_AKR13A_13D, AKR13A and AKR13D families of aldo-keto reductase (AKR). Schizosaccharomyces pombe aldo-keto reductase YakC is a founding member of aldo-keto reductase family 13 member A1 (AKR13A1). It catalyzes the reversible reduction of ketones to the respective alcohols using NADP(+) as a hydride donor. Rauvolfia serpentina PR is a founding member of aldo-keto reductase family 13 member D1 (AKR13D1). It catalyzes the NADPH-dependent reduction of the aldehyde perakine to yield the alcohol raucaffrinoline in the biosynthetic pathway of ajmaline in Rauvolfia, a key step in indole alkaloid biosynthesis. This family also includes Arabidopsis thaliana aldo-keto reductases, ALKR1-6.	4.29837e-165
NC_010511.1\|WP_012330401.1\|501004_501514_-\|pyridoxamine-5'-phosphate-oxidase-family-protein	gnl\|CDD\|379804	pfam16242, Pyrid_ox_like, Pyridoxamine 5'-phosphate oxidase like. This domain, approximately 140 residues in length, is mainly found in general stress proteins in various Xanthomonas species. It is composed of a six-stranded antiparallel beta-barrel flanked by five alpha-helices and can bind to FMN and FAD, suggesting that it may help the bacteria to react against the oxidative stress induced by the defense mechanisms of the plant.	7.75394e-63
NC_010511.1\|WP_012330398.1\|496465_497254_-\|histidinol-phosphatase	gnl\|CDD\|238819	cd01641, Bacterial_IMPase_like_1, Predominantly bacterial family of Mg++ dependend phosphatases, related to inositol monophosphatases. These enzymes may dephosphorylate fructose-1,6-bisphosphate, inositol monophospate, 3'-phosphoadenosine-5'-phosphate, or similar substrates.	2.09031e-115
NC_010511.1\|WP_012330387.1\|480795_482259_-\|peptidoglycan-binding-protein	gnl\|CDD\|237030	PRK12270, kgd, multifunctional oxoglutarate decarboxylase/oxoglutarate dehydrogenase thiamine pyrophosphate-binding subunit/dihydrolipoyllysine-residue succinyltransferase subunit.	1.07586e-09
NC_010511.1\|WP_012330400.1\|499559_500852_-\|nicotinate-phosphoribosyltransferase	gnl\|CDD\|235406	PRK05321, PRK05321, nicotinate phosphoribosyltransferase; Provisional.	0
NC_010511.1\|WP_012330405.1\|504815_505502_-\|phosphoribosylformylglycinamidine-synthase-subunit-PurQ	gnl\|CDD\|235140	PRK03619, PRK03619, phosphoribosylformylglycinamidine synthase subunit PurQ.	2.84935e-143
NC_010511.1\|WP_012330388.1\|482430_487728_+\|alpha-2-macroglobulin-family-protein	gnl\|CDD\|225248	COG2373, COG2373, Large extracellular alpha-helical protein [General function prediction only].	0
NC_010511.1\|WP_012330392.1\|492071_493007_-\|hydroxymethylbilane-synthase	gnl\|CDD\|234612	PRK00072, hemC, porphobilinogen deaminase; Reviewed.	4.67061e-149
NC_010511.1\|WP_012330397.1\|495303_496305_+\|alpha/beta-hydrolase	gnl\|CDD\|225176	COG2267, PldB, Lysophospholipase [Lipid metabolism].	1.2336e-56
NC_010511.1\|WP_012330386.1\|479852_480677_+\|alpha/beta-hydrolase	gnl\|CDD\|223730	COG0657, Aes, Esterase/lipase [Lipid metabolism].	1.27531e-10
NC_010511.1\|WP_012330389.1\|487749_488646_-\|LysR-family-transcriptional-regulator	gnl\|CDD\|176163	cd08474, PBP2_CrgA_like_5, The C-terminal substrate binding domain of an uncharacterized LysR-type transcriptional regulator CrgA-like, contains the type 2 periplasmic binding fold. This CD represents the substrate binding domain of an uncharacterized LysR-type transcriptional regulator (LTTR) CrgA-like 5. The LTTRs are acting as both auto-repressors and activators of target promoters, controlling operons involved in a wide variety of cellular processes such as amino acid biosynthesis, CO2 fixation, antibiotic resistance, degradation of aromatic compounds, nodule formation of nitrogen-fixing bacteria, and synthesis of virulence factors, to name a few. In contrast to the tetrameric form of other LTTRs, CrgA from Neisseria meningitides assembles into an octameric ring, which can bind up to four 63-bp DNA oligonucleotides. Phylogenetic cluster analysis showed that the CrgA-like regulators form a subclass of the LTTRs that function as octamers. The CrgA is an auto-repressor of its own gene and activates the expression of the mdaB gene which coding for an NADPH-quinone reductase and that its action is increased by MBL (alpha-methylene-gamma-butyrolactone), an inducer of NADPH-quinone oxidoreductase. The structural topology of this substrate-binding domain is most similar to that of the type 2 periplasmic binding proteins (PBP2), which are responsible for the uptake of a variety of substrates such as phosphate, sulfate, polysaccharides, lysine/arginine/ornithine, and histidine. The PBP2 bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap. After binding their specific ligand with high affinity, they can interact with a cognate membrane transport complex comprised of two integral membrane domains and two cytoplasmically located ATPase domains. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis.	1.12396e-103
NC_010511.1\|WP_012330402.1\|501687_501897_+\|TOBE-domain-containing-protein	gnl\|CDD\|226113	COG3585, MopI, Molybdopterin-binding protein [Coenzyme metabolism].	1.72079e-18
NC_010511.1\|WP_012330403.1\|501902_502943_+\|iron-ABC-transporter-substrate-binding-protein	gnl\|CDD\|238567	cd01147, HemV-2, Metal binding protein HemV-2. These proteins are predicted to function as initial receptors in ABC transport of metal ions. They belong to the TroA superfamily of helical backbone metal receptor proteins that share a distinct fold and ligand binding mechanism. A typical TroA protein is comprised of two globular subdomains connected by a single helix and can bind the metal ion in the cleft between these domains. In addition, these proteins sometimes have a low complexity region containing a metal-binding histidine-rich motif (repetitive HDH sequence).	6.50729e-75
NC_010511.1\|WP_012330396.1\|494604_495072_-\|Hsp20-family-protein	gnl\|CDD\|182691	PRK10743, PRK10743, heat shock chaperone IbpA.	5.04647e-52
NC_010511.1\|WP_012330394.1\|493358_493658_-\|antibiotic-biosynthesis-monooxygenase	gnl\|CDD\|367760	pfam03992, ABM, Antibiotic biosynthesis monooxygenase. This domain is found in monooxygenases involved in the biosynthesis of several antibiotics by Streptomyces species. It's occurrence as a repeat in Streptomyces coelicolor SCO1909 is suggestive that the other proteins function as multimers. There is also a conserved histidine which is likely to be an active site residue.	6.44977e-13
NC_010511.1\|WP_012330399.1\|497351_499391_-\|AI-2E-family-transporter	gnl\|CDD\|223701	COG0628, yhhT, Predicted permease, member of the PurR regulon [General function prediction only].	9.61363e-62
NC_010511.1\|WP_012330404.1\|502939_503992_+\|iron-ABC-transporter-permease	gnl\|CDD\|223682	COG0609, FepD, ABC-type Fe3+-siderophore transport system, permease component [Inorganic ion transport and metabolism].	5.05393e-68

>NC_010511.1|WP_012330395.1|493964_494390_+|hypothetical-protein
MTTLKEFEEALREHGMLMALALLERLRERDRANRTVKPGRRIVGKKMTPELARAILDLHGSTEMTQQEIAFKLGVNQGRVNEVIKRGKWLSGDQAAPEAVARDKGKARIRGTDVKRPRKGKEKAPTPRKPKAQTELLFGDP
>NC_010511.1|WP_012330394.1|493358_493658_-|antibiotic-biosynthesis-monooxygenase
MVLEIAQIEVKPGHEAAFEDGVAEAAALFRRAKGCKGMELHRSIEHPTRYRLMVKWETLENHTVDFRSSPDFQAWRDLVSDHFAAPPAVEHTTTTAAGF
>NC_010511.1|WP_012330393.1|493090_493315_-|hypothetical-protein
MTADRTQPDRDQPRRAGDQPRRGGDQPRREGLAESSLATSRRPAGHAPGQPAEPPHPAGTPQGEPVADEQIPRD
>NC_010511.1|WP_012330392.1|492071_493007_-|hydroxymethylbilane-synthase
MAHRPLRIGTRGSPMALAQTGMVRDRIAAAHPHLAEPGAMELVVVNTVADRILDRPLSAIGGKGLFTKELEQALFAGEIDVAVHSMKDVETWLPDGLVIACILERDDPRDAFLSLASGSLAELPAGARVGTSSLRRGAQVLMRRPDLRIVPLRGNANTRIRKLEEGVCDATLLAIAGLERLGLAHLARTVIPVEEMLPAVAQGALGIECRAADEDVIALLQAVACPRTTTALAAERGLLAELDGSCRTPIAALAQIDGDRLTLDGLLFLPDGSAHWATTRSGPAAEAASIGREAGADLKAQAGETYRRHLQ
>NC_010511.1|WP_018262812.1|489802_491935_+|penicillin-binding-protein-1C
MLGRSVRAGGGMAGGAAGRNGAWRRVVPALLLAAALAAGAAGLWREIGRDPGLDLAAAERRSPVVLDRAGVLLRPFATADGRWRLPLAPEAVDPRFLTLLMAYEDRRFARHPGVDPLAVLRAAGQWLRAGRIVSGGSTLSMQVARLVEPRAERSLAAKLRQVRGAVALERRLGKAGVLRLYLALAPYGGPLEGVRAASLAYFGHEPGRLSLAEAALLVALPQAPEARRPDRFPEAARRARDRVLDLAAARGAVRRDEAEAAKAEPVPQRRRPFPMLAAHAAEAALAEAPDRAVHRLTIDARLQASLEALAAERVAALGPGLSTAILVVDNATGAVRAHVGSAGYLDAGRAGAIDMAAALRSPGSALKPFVYALAFELGLAHPETLIEDRPSRFGAAYAPENFDLTFQGTVTARRALQMSLNVPAVELMELVGPARFIARLRAGGAGIALPRDAAPGLPVALGGLGITLTDLARLYAGLARGGLVPDLVRRPEAGPPAREPPRIAEGVAAWYVTDILRGTPPPENALPNRIAYKTGTSYGYRDAWAVGFDRRITVAVWVGRPDGASVPGLVGRVAAAPILFDAFARCGGEPEPVPPVRDALVTSTAGLPPPLRHLRRDAAKVAGEAPGAPLRIAYPPDGARVDLGFAEGAPAGLALKALGGTLPLTWMVNSLPLPEAARRQAEWQPDGAGFARISVMDATGASDSVVVRLE
>NC_010511.1|WP_012330390.1|488741_489728_+|aldo/keto-reductase
MRQRPLGRSGLTVSLPGLGCMGMSEFYGPADDAQSRAALEAALALGYDFLDTADTYGHGHNEALIGAVLAGRRDRAVVATKFGIVRAPGRYERRIDNSPAYVAAACEASLRRLGVETIDLYYCHRRDPAVPIEEVVGAMARLVEAGKVRALGLSEVSPATLRAAQAVHPIAAVQSEYSLWTREPEQGLLAACRDLGVALVAYSPLGRGFLTGAVDVAGLAQDDVRRANPRFRDEALARNARLAAALGTFAAERGASAAQVALAWLVTREPHVIPIPGTRKEARLAENAAAMEIRLTPEDLRALDALFAPGAVAGSRYDEAGMVGIETD
>NC_010511.1|WP_012330389.1|487749_488646_-|LysR-family-transcriptional-regulator
MPRSDLSDLVAFARVARHRSFRRAAAELGLSPSALSHALRDLEARLGARLLNRTTRSVAPTEAGAALLARLGPALDEIDRALGEVAASGGRLTGTLRLNAPRSACRLVLAPLAARFLSRHPGLRLEIACDDALADIVREGFDAGVRFGERVPRDMIAVPLGGRQRFAVVGSPAYLAARGLPATPEDLAGHACLRQRFAGGAVMRWEFERDGRALALDLDGPLILNEQELLLQAAVEGSGLAQVFEGYAAPFLAEGRLVRLLEPWCPSFPGFLLYHPSRRQPPPPLRAFLDFVRESAAA
>NC_010511.1|WP_012330388.1|482430_487728_+|alpha-2-macroglobulin-family-protein
MLRATRTGRLAGALAVALTLIVPAAAQAPQPPRPAPSALVPPPKDPAPKGFVRQDLASEAVRLEAEIRSDAAGKPQKPAAQWRREAEKLFKDDDHDGALAAYAGAIAAEPGDWKTWYALAETANGVENDDYDENQKLRRRARAGAYLAYQRAASRADEAKALALLGRVLADQESWRPALDAYKASLALADASDIRAAYEELREKHGFRITDYKVDSEAAAPRACFTFSEDLSAKTDMAPFVAVSGAANAAVTAEGQQVCVDGLKHGERYAVVLRQGLPSAIAGETLRKSADYEIYVRDRSPQVRFTGRNYVLPRTGQAGVPLVSVNAPKLDVEVLRIGDRGLLPTLRSEEFLSQLTGATARTLAREKGVRVWKGTLDTAGAEPNQEVVTAFPVLQAVGKIEPGLYVMLAQPSGTAALGDEETGGYDQQATQWFVVSDLGLTALKGADGVHVFVRSLASAATVQGAEIRLVARNNEVLGVRTTDAQGHAAFDPGLSRGEGGIAPSLVVARLGDDYGFLDLALSAFDLADRGVKGRPAPAAAEAFVFPERGVYRSGETVQITALLRDAKGAAIPGLPLTLVVKRPDGIEYRRAAVPDAGLGGRAFPLPLLPGAAPGTWRVLAYTDPKAAPVGEASFLVEDYLPERLEVTLTPKAPALAPNQPAVIDVAARFLYGAPGANLQVGGSVAVQAAASSGIRGLDGFAIGLDDESVVPTTAEIDERVTTDAQGRATVRAPVPALSAPRPLEAKVSLQVGEPGGRAVQRSVTLPILPAGPVVALRKTFGDLREGGTATFEVVAAQPDGTRLPARGAAWTLKKVERNYQWYRADGRWSYEAVRTSRKVANGALDLAPDAPARIAAPVEFGTYRLEVSAPNLQAASLSFTVGTGGSESADAPDLLDLTLDKAAYASGETLKARFAPRFAGTATVAVVSDRVHEIRTLSVPAGGGAVEIPVKAEWGAGAYLVATAYRPLDQAAKRLPGRALGLAWFSVDRAARSLDVAVEAPAKVRPRGDLRLPIRLSGLKPGEEARVTVAAVDVGILNLTRYAAPDPFAFFFGQKALSTEIRDLYGYLIDGMQGTLGAIRSGGDAGGAELADAPPTQEPLVRYSGVVTVGPDGRAEVTFPLPAFNGTARVMVTAWTAGRVGSAAADVIVRDAVVLTGTLPRFLNVGDRSRLHVALDNVEGAAGDYAVDLDLSGPVVVPAEALTRKIRLEAGQRGAIEIPVTAAGPGVARLDLRLTGPGLDGAAGQSFALAVQPGTGALLRRSVRSLDPGASVTLSNDLLADLLPGTGTLTVSASPLAGLDVPALLQALDRYPYGCTEQTVSRAMPLLYVNRLASLDRLALDDKVDERIRGAIDRVLSRQDASGSFGLWSAANSEDLWLNAYVADFLTRARERGFPVPQTAFSLALDRLRNAVANTSEVSGGGMDLAYAAYVLARNGRPVMGDLRYLADTKLSDFSTPLARGQIAAALALLGDRGRAQKAFEAAVSALRGEKDKAEYRPDYGSRLRDGAGLIALAAETGLVRDSIAPLGAVIGEERASGRVTSTQENAWMVLAAEGLSKEAESMAFAVDGEAQGGPLYRSFKAAQLDAKPVTVTNRGTTSAQLVLGVAGSPIVPEPPEARGYTVERRYHRLDGSLVDVTQLRQNDRVVVVLKVTEDKARAARLLLVDRLPAGLEIDNPKLLDADAVPALSFVKSDVQPTHKEFRDDRFVAAYDRDPSQPAFLTVAYTVRAVTPGRYVHPAATIEDMYRPERYGRTAFGAMEVGAPR
>NC_010511.1|WP_012330387.1|480795_482259_-|peptidoglycan-binding-protein
MPRRLALLLAVLLSLPAAAQQPAPRPGPAPAPKPAPAPKPAPAPKPAPAPKPAPESKPAPAAPPADAAFEAARAAFEARPEAERRAVQEALVWASDYTSVTTGTFGRRTYEALVAWQGQNGLEPSGLLDERARARLLAAGQAAKQAAQFTLQADAATGITLGVPERLLSRRGRIPNGSRWQSPDGRVTLDTKAFAPGETDLDALFEKAASVSPERKVTYKLKRPDFVVVTGETPQGKFYIRYAAGPAGLRGFSLAYDKALAREVDRLVIAVANSFAPFPSEAPAAPPAAATAAAPIAPAPAGSSATGLAVGPRRLVTAAAAMAACPAPLVAGAPARVVRQEAGLALLETERPLSPGTLPPAAPAAPAPGEDLVVLGMGRDGAPTVAPGVAGAAGGVVAPLQPGAAGAPVLDRAGRLVGFVAQMPAQPRLIAGVMPPLTHPVVGVAALRGLGAAEGAALPPSGPAAPKSAGAIAAPLAGALVAVQCRG
>NC_010511.1|WP_012330386.1|479852_480677_+|alpha/beta-hydrolase
MPDAMPDAWRAMDRAALSAAYDNSGAVAGSAAIVAGWRERSAALRQAHPAELDLGYGAEARQRLDLFRCGAAGAPLLAFLHGGYWQRNAKEGFACMAEGPLARGLDVALIGYTLAPEASLTRIAEEVGAALAVLRRREAGRLVVSGWSAGGHLAALALTRGQADAALAVSGIFDLAPIRGTALNDALNLSPEEVEALSPIRHLPAASGPLTVAYGAEELPELRRQSETYGAAWRAAGLPGALRPLPGHDHFSVLSELIRPDGALTEAAVALARG
>NC_010511.1|WP_012330396.1|494604_495072_-|Hsp20-family-protein
MRQFDLAPLYRSTVGFDRLFSALDQFVSAEAAPTYPPYNIERTGETAYRITVAVAGFTDQDLSIEVRENALTIKGERKAAEARKGEFLHQGIAARSFERRFQLADYVQVTGATLENGLLHVDLVREIPEAKKPRQIQIATGSAPRSIEGTVQQAA
>NC_010511.1|WP_012330397.1|495303_496305_+|alpha/beta-hydrolase
MTVPLIATPDNPIPPGARTLAVPTRDGLTLRAATWTAATRTTKGTVCLVQGRAEFIEKYYETVQDLRARGFAVAAFDWRGQGGSDRTVADARKGHVGDFEEYRLDLEAVATQVLEPLMPRPYFGLAHSMGGAVCLAAAREGWLPFSRLVTLAPMLGIVMVRHPRAAMRAAALLNGLGLGPRFVPGGSPVSIATKPFPGNRLTTDPARYARNAAAALAVGAGAVGDPTVAWLAAAFRTMRRLGDPRYPLAIRLPVLVVAAGDDPVCSTPAIERFAARLKAGHSITLRGARHEILMEQDAIRAQFWAAFEAFVPGTPLPEPREEDLIALERLPPG
>NC_010511.1|WP_012330398.1|496465_497254_-|histidinol-phosphatase
MSVVDFARFVDELATQSGQAILPFFRAAFVTEDKAIGPKPFDPVTEADRAGEAVMRQIIRRTFPDHGILGEEFGTEGEEAEYVWVLDPIDGTRGFIAGLPLWGTLIGLTRAGTPCYGLMHQPFLGERFSGDGRSAQYRGPNGTRKLLTRRRAALSEAIAATTDPRLFGEGRDREAYGRVEAATRLMRFGTDCYSYCMLAAGQIDLVIEAGLKPYDIVALIPIVEGAGGIVTSWDGGPAAGGGNVVAAGDKRLHEAALEMLNR
>NC_010511.1|WP_012330399.1|497351_499391_-|AI-2E-family-transporter
MARDDGGQASLIPAVPKRIAAAETPGRGFALPLLIAALIVAALYFGREILIPIAIAVLLSFVLWPLVSLLRRLRLGRTASIGLSVLTCLGVVGLLTLVIGLQVADLGSNLPQYQRTIERKLENLREGPVGSIAGYMRSIGKHLQQAGSIPEDKAKPQDPTAPRPAPSVQNPDKPVLVEVRERELTPLELAERLLSPALAPLATTGIVFVVLMFILGQREDLRDRLIRLAGSSDLHRTTVAMNDAARRLSRFFLVQLALNAGFGVAIGIGLWIIGVPSPILWGIFTALMRFVPYVGAFLSALLPLLLAAAVDPGWHMVLATAALFLILEPIVGQVVEPLLYGHSTGLSPFAVLVSALFWTWLWGPVGLLLSTPLTVCLVVLGRHVDQLEFLDVLFGDRPALTPVENFYQRLLADDPDEAQELAESILSECSLSSYYDDVVLKGLQLAASDARRGVLTEEQLERIRTAIDELVTDLADREDVAPAAQTSLAGRLLGRDADAAAPCDGEPAVPGAPAPETLPAPWRQKGAVLCVAGRGPLDEAASTMLSQLLEKNGLGTRVVPFAAVSRARIADLDAGEARMVCISYLEISGTPAHLRYLVQRVRRRLPQARILVGLWPTDDLALADPEARAALGADDHVTSLREAVEACLAAATGEAASAGRPAPVAPAPRSASLPAGAPA
>NC_010511.1|WP_012330400.1|499559_500852_-|nicotinate-phosphoribosyltransferase
MLDLATRVYNHTWKIDPIIRSVLDTDFYKLLMAQTIFRRHRDVEVTFGIHNRTTRVRLGEIIDEGELREQLDHCRSLRLTRGESTWLRGNTFYGKRQMFSPDFMDWLENFRFPDYLLEKQDGQYVLTFHGPWIETTMWEVPALSILNELRSRGVLKGMGKFDLQILYARAMTRIWEKIERLKLLPGLSIADFGTRRRHGFLWQDWCVEAMIEGLGPAFLGTSNCLIALRHDIEAVGTNAHELPMVYAALAEDDAALARAPYAVLADWQQDYAGNLLVILPDTYGTTGFLANGPAWMADWTGIRIDSKDPIIGGEEVIAWWRENGRNPREKLAIFSDGLDVDTIETIHHRFHGRLRIGYGWGTLLTNDFRGLAPDGRLDPISIVCKVISANGRPTVKLSDNPTKALGPEEEVERYKRVFSVGAQVAQPLLV
>NC_010511.1|WP_012330401.1|501004_501514_-|pyridoxamine-5'-phosphate-oxidase-family-protein
MHQGSHRDHEGAQKLFSLIKDVKVAMMTTVDSDGQLRSRPMWSQEADPQGDLWFFVRLDAPVTGEISRDSQVNLAYADPSNQNYVSVSGKAEIVRDKATIDSKWNESLKTWFPKGKDDPSVTLIRVHPEKGEYWDSPNATMLHLYGYVKAAVTGESPKTEKKAVDLSAR
>NC_010511.1|WP_012330402.1|501687_501897_+|TOBE-domain-containing-protein
MRISARNQLSGTITSVTKGTTTAHVTLELPGGQVVTAALTNDSVDGLHLAVGKPAVAVIKSGDVTIAVD
>NC_010511.1|WP_012330403.1|501902_502943_+|iron-ABC-transporter-substrate-binding-protein
MALDRRALLLGLAGLCAAGRARAAGRTRAAGLDEAGRPLPAPSGPVTRVFPAGPPAAILLYTLAPDLLAGWPRAIRPAERPYLLPEAAALPEVGRLTGRGNTANLETVLALKPDLVVDTGDTGETYRSLADRLQQQTGIPALLFDGRLPAVPATYRRLGAVIGRAERAERLAARCEAILNTVQGRLAAVPPEARPRVYFARGPRGLETARAGAINVEVLDLLGAVNVAGAGGSLARVSPEDVLAWAPEVIVALDPGFAAAARTDPLWQGVPAVAAGRLHLSPALPFGWVDSPPSVNRFLGLWWLGKALYPSLFPEDLRALARDFHRDFYHVVPDEAALDRLLAGAS
>NC_010511.1|WP_012330404.1|502939_503992_+|iron-ABC-transporter-permease
MSGPPARAEGRIGARRAPGLGPALALGALILAVALAFGVGRYPVGLGDVARVLAAKLTGAPSGAPAAVEAVVLQIRGPRILAAILIGAALSLAGAAFQGLFRNPLVSPDILGASSGAAFGAVLGIWLSLGVLAIEVLAFAGGLLAVGAVYAVGAVLARRDPVLVLVLAGVVIGSLLGAGVGLVKFLADPYNQLPAMTFWLLGSLSATHATDLAALAVPVAAGTALLLLLRWRLDALSLPDEEARALGLATGPLRLAVVAAATLVTAASVAAAGIVGWVGLVVPHLARFLVGPGFARLLPTAALLGAGTLLVIDTLARTVAPVEVPLGILTAVVGTPVFLWLLAGAERDWS
>NC_010511.1|WP_012330405.1|504815_505502_-|phosphoribosylformylglycinamidine-synthase-subunit-PurQ
MKAAVIVFPGSNRDADVTRALRLAGAEVAKVWHADTALPSGTDLAVLPGGFSYGDYLRCGAIAGRANAMDAVRAHAARGGLVLGICNGFQILCESGLLPGVLMRNVNRRFICHRQTLRVERADTAFTRAYRQGQVIDVCVAHGEGNYYADPETVARLEGEGRVAFRYSDAAGDLTETANRNGSLNSIAGIYSDELNVLGLMPHPENFVEDLVGGTDGRGLFESLARAA

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Crispr_ID: NC_010511_4

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_010511_4

568001-568091

Orphan

Consensus_repeat	Method
AAGCCCGCGCGGCGCGTGAGCGA	CRISPRCasFinder

1 spacers

The CRISPR arrays of NC_010511_4

>merge|NC_010511|4|568001-568091|CRISPRCasFinder
AAGCCCGCGCGGCGCGTGAGCGAAGCTGAAATCCGCATGGCGACGCAATCCGTCGGATCTCGTACGACAAGCCCGCGCGGCGCGTGAGCGA

>NC_010511|4|4|568001-568091|CRISPRCasFinder
AAGCCCGCGCGGCGCGTGAGCGA	AGCTGAAATCCGCATGGCGACGCAATCCGTCGGATCTCGTACGAC
AAGCCCGCGCGGCGCGTGAGCGA

Protein	Signature genes	Signature genes Name	Protein_function
NC_010511.1\|WP_012330460.1\|562521_562803_-\|hypothetical-protein	unknown	unknown	unknown
NC_010511.1\|WP_012330472.1\|580477_581215_-\|nucleotidyltransferase-family-protein	unknown	unknown	gnl\|CDD\|133044
NC_010511.1\|WP_012330470.1\|576733_577294_+\|cytochrome-b	unknown	unknown	gnl\|CDD\|225580
NC_010511.1\|WP_012330455.1\|556689_557598_-\|outer-membrane-beta-barrel-protein	unknown	unknown	gnl\|CDD\|226163
NC_010511.1\|WP_012330468.1\|572501_572849_+\|hypothetical-protein	unknown	unknown	unknown
NC_010511.1\|WP_012330456.1\|557929_559255_-\|bifunctional-folylpolyglutamate-synthase/dihydrofolate-synthase	unknown	unknown	gnl\|CDD\|223362
NC_010511.1\|WP_012330462.1\|563923_564556_+\|cysteine-hydrolase	unknown	unknown	gnl\|CDD\|238496
NC_010511.1\|WP_012330461.1\|562952_563807_-\|LysR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|223656
NC_010511.1\|WP_012330464.1\|565466_567962_+\|DUF1929-domain-containing-protein	unknown	unknown	gnl\|CDD\|199882
NC_010511.1\|WP_012330471.1\|577358_580481_-\|double-strand-break-repair-protein-AddB	unknown	unknown	gnl\|CDD\|274300
NC_010511.1\|WP_012330459.1\|561513_562515_-\|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|224050
NC_010511.1\|WP_012330473.1\|581251_582796_-\|bifunctional-tRNA-(adenosine(37)-N6)-threonylcarbamoyltransferase-complex-ATPase-subunit-type-1-TsaE/phosphotransferase	unknown	unknown	gnl\|CDD\|225719
NC_010511.1\|WP_012330467.1\|571932_572133_-\|Trm112-family-protein	unknown	unknown	gnl\|CDD\|225391
NC_010511.1\|WP_012330458.1\|560613_561441_-\|tryptophan-synthase-subunit-alpha	unknown	unknown	gnl\|CDD\|237285
NC_010511.1\|WP_012330469.1\|573039_576513_-\|double-strand-break-repair-helicase-AddA	unknown	unknown	gnl\|CDD\|274298
NC_010511.1\|WP_012330465.1\|568315_568660_+\|DUF2293-domain-containing-protein	unknown	unknown	gnl\|CDD\|370799
NC_010511.1\|WP_012330463.1\|564777_565449_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|239266
NC_010511.1\|WP_012330474.1\|583262_584426_-\|N-acetylglucosamine-6-phosphate-deacetylase	unknown	unknown	gnl\|CDD\|224733
NC_010511.1\|WP_012330457.1\|559591_560503_-\|acetyl-CoA-carboxylase-carboxyltransferase-subunit-beta	unknown	unknown	gnl\|CDD\|235547
NC_010511.1\|WP_012330466.1\|568739_570932_+\|primosomal-protein-N'	unknown	unknown	gnl\|CDD\|235514

Protein	Function_ID	Function_description	E-value
NC_010511.1\|WP_012330471.1\|577358_580481_-\|double-strand-break-repair-protein-AddB	gnl\|CDD\|274300	TIGR02786, conserved_hypothetical_protein, double-strand break repair protein AddB, alphaproteobacterial type. AddAB is a system well described in the Firmicutes as a replacement for RecBCD in many prokaryotes for the repair of double stranded break DNA damage. More recently, a distantly related gene pair conserved in many alphaproteobacteria was shown also to function in double-stranded break repair in Rhizobium etli. This family consists of AddB proteins of the alphaproteobacteial type. [DNA metabolism, DNA replication, recombination, and repair].	0
NC_010511.1\|WP_012330470.1\|576733_577294_+\|cytochrome-b	gnl\|CDD\|225580	COG3038, CybB, Cytochrome B561 [Energy production and conversion].	3.37218e-30
NC_010511.1\|WP_012330455.1\|556689_557598_-\|outer-membrane-beta-barrel-protein	gnl\|CDD\|226163	COG3637, COG3637, Opacity protein and related surface antigens [Cell envelope biogenesis, outer membrane].	1.02444e-05
NC_010511.1\|WP_012330456.1\|557929_559255_-\|bifunctional-folylpolyglutamate-synthase/dihydrofolate-synthase	gnl\|CDD\|223362	COG0285, FolC, Folylpolyglutamate synthase [Coenzyme metabolism].	4.09652e-140
NC_010511.1\|WP_012330462.1\|563923_564556_+\|cysteine-hydrolase	gnl\|CDD\|238496	cd01014, nicotinamidase_related, Nicotinamidase_ related amidohydrolases. Cysteine hydrolases of unknown function that share the catalytic triad with other amidohydrolases, like nicotinamidase, which converts nicotinamide to nicotinic acid and ammonia.	1.14498e-60
NC_010511.1\|WP_012330461.1\|562952_563807_-\|LysR-family-transcriptional-regulator	gnl\|CDD\|223656	COG0583, LysR, Transcriptional regulator [Transcription].	4.74957e-20
NC_010511.1\|WP_012330464.1\|565466_567962_+\|DUF1929-domain-containing-protein	gnl\|CDD\|199882	cd02851, E_set_GO_C, C-terminal Early set domain associated with the catalytic domain of galactose oxidase. E or "early" set domains are associated with the catalytic domain of galactose oxidase at the C-terminal end. Galactose oxidase is an extracellular monomeric enzyme which catalyzes the stereospecific oxidation of a broad range of primary alcohol substrates and possesses a unique mononuclear copper site essential for catalyzing a two-electron transfer reaction during the oxidation of primary alcohols to corresponding aldehydes. The second redox active center necessary for the reaction was found to be situated at a tyrosine residue. The C-terminal domain of galactose oxidase may be related to the immunoglobulin and/or fibronectin type III superfamilies. These domains are associated with different types of catalytic domains at either the N-terminal or C-terminal end and may be involved in homodimeric/tetrameric/dodecameric interactions. Members of this family include members of the alpha amylase family, sialidase, galactose oxidase, cellulase, cellulose, hyaluronate lyase, chitobiase, and chitinase, among others.	5.88283e-23
NC_010511.1\|WP_012330472.1\|580477_581215_-\|nucleotidyltransferase-family-protein	gnl\|CDD\|133044	cd06422, NTP_transferase_like_1, NTP_transferase_like_1 is a member of the nucleotidyl transferase family. This is a subfamily of nucleotidyl transferases. Nucleotidyl transferases transfer nucleotides onto phosphosugars. The activated sugars are precursors for synthesis of lipopolysaccharide, glycolipids and polysaccharides. Other subfamilies of nucleotidyl transferases include Alpha-D-Glucose-1-Phosphate Cytidylyltransferase, Mannose-1-phosphate guanyltransferase, and Glucose-1-phosphate thymidylyltransferase.	4.67125e-107
NC_010511.1\|WP_012330463.1\|564777_565449_+\|hypothetical-protein	gnl\|CDD\|239266	cd02968, SCO, SCO (an acronym for Synthesis of Cytochrome c Oxidase) family; composed of proteins similar to Sco1, a membrane-anchored protein possessing a soluble domain with a TRX fold. Members of this family are required for the proper assembly of cytochrome c oxidase (COX). They contain a metal binding motif, typically CXXXC, which is located in a flexible loop. COX, the terminal enzyme in the respiratory chain, is imbedded in the inner mitochondrial membrane of all eukaryotes and in the plasma membrane of some prokaryotes. It is composed of two subunits, COX I and COX II. It has been proposed that Sco1 specifically delivers copper to the CuA site, a dinuclear copper center, of the COX II subunit. Mutations in human Sco1 and Sco2 cause fatal infantile hepatoencephalomyopathy and cardioencephalomyopathy, respectively. Both disorders are associated with severe COX deficiency in affected tissues. More recently, it has been argued that the redox sensitivity of the copper binding properties of Sco1 implies that it participates in signaling events rather than functioning as a chaperone that transfers copper to COX II.	5.77621e-17
NC_010511.1\|WP_012330473.1\|581251_582796_-\|bifunctional-tRNA-(adenosine(37)-N6)-threonylcarbamoyltransferase-complex-ATPase-subunit-type-1-TsaE/phosphotransferase	gnl\|CDD\|225719	COG3178, COG3178, Predicted phosphotransferase related to Ser/Thr protein kinases [General function prediction only].	1.67601e-112
NC_010511.1\|WP_012330467.1\|571932_572133_-\|Trm112-family-protein	gnl\|CDD\|225391	COG2835, COG2835, Uncharacterized conserved protein [Function unknown].	1.72855e-23
NC_010511.1\|WP_012330458.1\|560613_561441_-\|tryptophan-synthase-subunit-alpha	gnl\|CDD\|237285	PRK13111, trpA, tryptophan synthase subunit alpha; Provisional.	3.36466e-133
NC_010511.1\|WP_012330469.1\|573039_576513_-\|double-strand-break-repair-helicase-AddA	gnl\|CDD\|274298	TIGR02784, ATP-dependent_nuclease_subunit_A, double-strand break repair helicase AddA, alphaproteobacterial type. AddAB, also called RexAB, substitutes for RecBCD in several bacterial lineages. These DNA recombination proteins act before synapse and are particularly important for DNA repair of double-stranded breaks by homologous recombination. The term AddAB is used broadly, with AddA homologous between the alphaproteobacteria (as modeled here) and the Firmicutes, while the partner AddB proteins show no strong homology across the two groups of species. [DNA metabolism, DNA replication, recombination, and repair].	0
NC_010511.1\|WP_012330465.1\|568315_568660_+\|DUF2293-domain-containing-protein	gnl\|CDD\|370799	pfam10056, DUF2293, Uncharacterized conserved protein (DUF2293). This domain, found in various hypothetical bacterial proteins, has no known function.	9.4378e-22
NC_010511.1\|WP_012330474.1\|583262_584426_-\|N-acetylglucosamine-6-phosphate-deacetylase	gnl\|CDD\|224733	COG1820, NagA, N-acetylglucosamine-6-phosphate deacetylase [Carbohydrate transport and metabolism].	3.81184e-127
NC_010511.1\|WP_012330457.1\|559591_560503_-\|acetyl-CoA-carboxylase-carboxyltransferase-subunit-beta	gnl\|CDD\|235547	PRK05654, PRK05654, acetyl-CoA carboxylase carboxyltransferase subunit beta.	5.57679e-175
NC_010511.1\|WP_012330459.1\|561513_562515_-\|ABC-transporter-ATP-binding-protein	gnl\|CDD\|224050	COG1125, OpuBA, ABC-type proline/glycine betaine transport systems, ATPase components [Amino acid transport and metabolism].	5.09359e-134
NC_010511.1\|WP_012330466.1\|568739_570932_+\|primosomal-protein-N'	gnl\|CDD\|235514	PRK05580, PRK05580, primosome assembly protein PriA; Validated.	0

>NC_010511.1|WP_012330464.1|565466_567962_+|DUF1929-domain-containing-protein
MTRRLPLAAQRARRLLLATTILGALPAFPALAAQFGVVVNPVQDPLFANLAIPDSAPATGMWSAVQAWPLNAISTALLPNGKLVSWGTPVNAPGTQDGHSFAIWDPYQGFAPGSHTILPGVLNVNSFCGTQALQADGSLLVSGGIFDNGNDKGSAVVNTGATGVSALGARLAADRYYATMITLADGQKLIMGGAYPYASGWGDPNGSIAKGLMSGMTPEIYNPATGWRSLFGANSRDAFGPDFNRWWYPRAWVAPNGKVFGITSDRMWFLDPTGNGSVWAMPFRAPQRSVTVATDAPNVGPNSTAVMYDAGKILQVGGNSYDNGTGFLASSRATMIDINGNAPIANDIAPMNIGRSWANATVLPTGTVAVTGGSKSVDAAGGDTVLEAELWDPRTGQWTLGPRAAIYRGYHSSAVLLQSGAVLTSGGGAPGPVSNQNSEVYYPPYLFTTVNGKAALAPRPQIVSLNTVSLAHGQSLQFEFTSANGLAQVALLGLSQGTHSFNTGQRRSLLTFTQAGQVATVQAPATPALAPPGYYQIVAIDQKGVPSPGVIIALGSGVAPPPQVAAPVGNVAQGGVTPPPPPPPAPPLPPPAPPPAPPPAPPPPPPAPTDLWLPIGNTAKRIAVGRDGTLVMLNAVDGSLSKYAPDKTWVKLAGNFKDVAVVDANSIYGIQMDGVIVRFNGQTWRRVGYGGKTISASADGTIVIVNILNEIWKKYGDNDQEAWGQIPGKAQRVAAMNANSFWSVGLDGDVYRADQTGKWVLVGSNAVDIAASPDGSVAVINSDVGVLWRKFGDDTVEAWGWVKTPGPAQAVAVPNGQHAFVIGRDGVIYRQ
>NC_010511.1|WP_012330463.1|564777_565449_+|hypothetical-protein
MATPRAVRIGALLLGLVALAGSVPAAPGGALGPEGGRPSAIEDLVWPDAPGTRIRRDQSGRPLTPETLRDKVAVVGFVSTQCPITCVVLARELDALAGALPPSLRDRVVIVAVTVDPARDDVAALRRFGEGMGIDPGRVRLVTSDPAATAHQAALLRYPADRLPLPPPRLLVFDRRGDLAMIYGTEPVDRPRLLTDLALLERFEAGIHAPPRPDGAPLPASNP
>NC_010511.1|WP_012330462.1|563923_564556_+|cysteine-hydrolase
MHEPRTLLQLAGATPTPARIARAVLVVIDAQGEYADGALPLDGFGPALAAVRALLAAAREAGAPVVHVAHRGRDGGLFDRGGPGGAIVPEALPRPGEPVIEKTLPNAFAGTDLAARLRDLGRTDLVLAGFMTHNCVSATARAALDLGYRVTVAGDATATRALPDPLGGPPLPAEAVQRAALAALADRTAVVAPAREIVAPAPGILGADAR
>NC_010511.1|WP_012330461.1|562952_563807_-|LysR-family-transcriptional-regulator
MESWDAWQTLLAVARTGRLSAAAGRLGIDATTAGRRVRRLEAALGRPLLAREGGLLVPTRTCLALMPRLEAAERALREVAGEAASDEAPGPGWRPVRVTAVAVLCDHLLAPAVPRLLAARPALGLDLIAEDRNLSLTRREADLALRLGPPARGAAAARPVGRLDYAVFAAAGEGAPERLPWAALDGALAHLPEVRFAERAAGRAGPRHRVSRLETLLRLTRAGGVRAVLPEIMAGRDPALRRLAPAVSRPIFLIGHPEDEGQPLVRAVASWIEGLLPPPADGPP
>NC_010511.1|WP_012330460.1|562521_562803_-|hypothetical-protein
MRMLLAPAILGLAILPDLAAAQQPDPTSPPGLAQPAPGVRGHRQPRPDTVGGKPEAGSAALPSPEDSARKAAARDKAWDAKMKRTLGSICSGC
>NC_010511.1|WP_012330459.1|561513_562515_-|ABC-transporter-ATP-binding-protein
MIRFEGAGKAYPGHARPVVDRLDLAVEEGTTCVLIGPSGCGKSTTLRMVNRLVTPSTGRVRVGGRDVAELDPIGLRRRTGYVLQGVGLFPHRSVAQNVATVPGLLGWPRRRIAERVDAMLDLVGLDPATFRDRRPDSLSGGQRQRVGVARALAADPPVLLMDEPFGAVDPLVRGRLQAEIGAILRRLGKTVLFVTHDIDEALRMGDRVALMREGRLVQVDPPERLLARPADPFAEEFVGADRWLRRLALIPAAAARTAGPPPRASLPPLASLPPLASLPPLASLPPQASLRDALSALVAGTDEAVGLAEGGVVTLSSLRAAAADSAGGFTSPP
>NC_010511.1|WP_012330458.1|560613_561441_-|tryptophan-synthase-subunit-alpha
MTTRLDDTFARCRAEGRAALVTYVMAGDPDPETSLQVLRALPEAGADIVEFGLPFTDPMADGPAIQAAGLRALKAGQTVSGTLALVRRFRAENRTTPVILMGYYNPLYIYGVARFLADAVAAGVDGLIVVDLPPEEDDELCLPTQEAGLAFIRLATPTTDERRLPAVLANTSGFVYYVSITGITGSATPDFGQVEAAVARIRARTALPVVVGFGVKTGAHAAAIARGADGVVVGSALVDALARSLDLDGRATSGSVAAVSALVRDLAAGVRAAAR
>NC_010511.1|WP_012330457.1|559591_560503_-|acetyl-CoA-carboxylase-carboxyltransferase-subunit-beta
MKVETMNWITEVVRPRIKTLFKRETPENLWVKCPETGQMVFHKEVEAHDFVIPGSEHHLRMSAQQRLKMMFDQGTWLDVPLPEAPVDPLKFRDEKRYVDRLKDARAKTGMADAFKVGFGRVGGLPMTLAVQDFGFMGGSLGMAAGEAFVRGAETALDKRTPYVLFAASGGARMQEGILSLMQMPRTTVAVRRLNRARLPYIVVLTNPTTGGVTASYAMLGDVHLAEPGALIGFAGPRVIEQTIREKLPDGFQRAEYLREHGMIDQVVHRRDLKATVARLCGLLMQAPAATPAPASAAAQPVPA
>NC_010511.1|WP_012330456.1|557929_559255_-|bifunctional-folylpolyglutamate-synthase/dihydrofolate-synthase
MESSDALMARFLALHPRTIDLSLGRIERLLAALGHPERRLPPVIHVAGTNGKGSTIATMRAILEAGGLSVHVYTSPHLVRFHERIRLGQVGGGRFVAEDRLADAFARCEAANAGEPITVFEITTAAALLLFAECPADVLLLEVGLGGRVDATNVIDRPAAAVVTPIGRDHAEYLGDTVEAVAGEKAGIFKRGCPAVIAPQDYAEADRVLCARAEALRAAPVLVGNQDFSVHEERGRLVYQDEEGLLDLPRPRLAGRHQIVNAGTAIAALRAAGFGDLGTAAFEAGLSQVDWPGRLQRLGRGRLPGLMPAGSELWLDGGHNVDGGRILAAAMADLQERGDAPLVLVTGLLGTKDAEGFLKNFVGLARAVVAVPISGQLAARPAEEVAAIAASVGLPATTAPSIEAALVALQDRAWEAPPRVLICGSLYLAGAVLTANGTPPV
>NC_010511.1|WP_012330455.1|556689_557598_-|outer-membrane-beta-barrel-protein
MKRLLSAFAAFTALTAAASAADLPRRVAPPVIAPVPVFTWTGFYAGFNAGYGFDASSTNPDVIVLTRDPRVVAGPAGSALAIGWTGDRNTEGFSGGGQIGYNYQFTPGAGVVVGIEADAQYVDFGRNRNAFSFAIPNQPGAQFNGANGLRLFDPRGLSGLDYFGTVRGRLGYAFDRVLFYGTGGFAYGGGGGTNFGLPNTDDFQTGWTAGGGIEYALPTDSFLNFFRSSAVTLKVEGLYVNLDRNRRNGAYAFDNAGVIVAGLPNSIILSNTAGFPAVGNLARRNTEFAVVRAGLNYKFGTW
>NC_010511.1|WP_012330465.1|568315_568660_+|DUF2293-domain-containing-protein
MPGRRPDPAPRQVPTRRERIAQAVARLAPRLPAFEAEAILDRALASPGLRGAAPENAAWLGMVAYARHVFTEYDALLAEGYDQDSARHFVLDDLNAVLAGWGVRRRIGEEAEEA
>NC_010511.1|WP_012330466.1|568739_570932_+|primosomal-protein-N'
MSAAIADVLIPLALDTAYSYAVPDGLTLAEGDVVQIPLGPRETVGVVWSLRESASGGNLRRVTGKIADDGMRTPLRRLVDWIARYTLAPKGSALAMALRLPEEGPRGETARIGVRATGMPPSRVTPARTKVLAVAADGAVRGKRALSLEAGVSASVVDGLIDDGVLETVALAPERVAEPPDPDHPHAALSEAQAEAARALIASLTAPPRTGGPAGDGGVTLLEGVTGSGKTEVYFEAVAEAVRRGVQSLVLMPEIALTAQFLDRFAARFGARPAAWHSGVGGRRRERIRAGVAAGEIPVVVGARSALFLPFRSLGLIVVDEEHEAAYKQEDGVCYHARDMAVVRAKLENAALVLASATPSIETRVNAQRGRYRRVVLPERFGGRRLPEIRAIDMRREQIPRGRYLSPTLTAAIAETNGRGEQALLFLNRRGYAPLTLCRACGHRYQCPNCSTWLVEHRFRRALVCHHCGHAERRPEACVACGTFDTLAACGPGVERIAEEVAATFPERRVIVLSSDFPGGAERLRAELQTVAEGGCDIVVGTQLVAKGHNFPHLTLVGVLDADIGLASGDPRAAERTFQLLQQVTGRAGRGEKPGRALVQTYQAEHPVIAALISGDAERFYEEETAARSMAGLPPFGRLAALIVSAAEREAAEAHGRALAQVAEPPPGVMVLGPAEAPLALVRGRHRFRLLVKAEREVDIQSYLRDWLARGPKPRGSVRVGIDVDPQSFL
>NC_010511.1|WP_012330467.1|571932_572133_-|Trm112-family-protein
MADTPSVEPTRIDPKLLELLVCPLTKGRLEYDSARQELISRSAKLAYPIRDGIPIMLPEEARPLAE
>NC_010511.1|WP_012330468.1|572501_572849_+|hypothetical-protein
MGLQTIRPFSVIRDIAATDAPARRGHAADSPVEIRGPASSEYWTIPSGLDVAEAREADPPRLTEATTSPLGTVAAAGLDAREAALTAARVRDALSSERLPIGNTAPQNLRTLFRV
>NC_010511.1|WP_012330469.1|573039_576513_-|double-strand-break-repair-helicase-AddA
MGIEGFVVDAVTQTAQRRAADPRASAWVSANAGAGKTKVLTDRVVRLLLHGAPPAKILCLTFTKAAAANMAIRVFERLGRWVTLPEEALRAELTALEGERPDPATLRRARRLFARAVETPGGLKIETLHALCERLLHLVPFEANVPARFVVLDEAQTREAVDRTIDNVLADAVDGTRPDLAQALARVAPEAAGEALRRAIGEAVRARAVLLHPQGLPARLERLREALGLAPDEAVGTIEARMREGAPADWAGLAAQLRTGKATDEKRADALARAAAAEEPQDLPLYLAAFFKDEGEGDPYAPASLGTKAVPEAVRRLLLDEQARLGRLRERLKAARAQERTAALFTLAAEIHRRVEAQKARLGALDFDDLIHKTLDLLTRVDSAWVLYKLDRGVDHVLIDEAQDTNPEQWEILRRITEDFCAGEGARRGPLPRTRFAVGDPKQSIYSFQGAAPEEFETTRQAWRRAARGAGLAFEDVGLTLSFRSAKGVLRGVDATFALAEHYRGLSFGDGAIGTVHETVRVGAPGQVELWPTEEPCEEPEPDAWVQPVDAVEAGAPALVVARRVARAVRHWTREGDEHGRIWRPGEILILVRKRSAAFEGVIRALKAEDVPVAGQDRLDIAAHIAVMDLVAAGRAALLPDDDLTLACALKTPLVGLTDDDLVRLAARRAPEESLAAALARHAGAGDPAALRGAAALATWRRLAQESGPFGFYADLLGPLGGRARLVARLGGEAGDAIDVFLTAAAQAEQGADAPSLTGFLSRYAPSGGRDAGGHTVKRDLESARDEVRVMTVHGAKGLEAGLLVLIDGCEPLGRNDPPLLPVPVRGAGGVADGTVPVWSPSKGHDCPAGAAAREALHERARQEHNRLLYVAMTRAKDRLVIAPYRGRDRETPESWCEMVRRGLVAAFGGVERAEMPYGPAETWRHGAALPAAPATAVPPAPPGERPDWLFRPVAPEAEPLPPLRPSGLGAADEPRRSQPRSGDPAARRRGVLIHALLEHLPALAPERRAAAARAFVAARAPGLPAAEREALATSVLRLLADPDLSVLFGPLARAEVALAGTVSLGGVEWPVHGRIDRLAVTEEAVWLCDFKTGRPPAEGAPVPGGMAAQVALYAALLARIHPDRAVIPLLVWTAGPVIRRLSGAECAAALAALRPA
>NC_010511.1|WP_012330470.1|576733_577294_+|cytochrome-b
MEVAMARSATAAPEEALVRYDTTTIVLHWLTALLVGLLWILGQTNDWWPRGPLRGGLWSLHVLLGFALMATLATRVVWRIGPGRALPSAEDGPLRLLARATHSGLYLLLIAVVGLGLADALVRGFVLFGAIPLPQVGDQALRRPINALHEWAANAVMAVAGLHAAAGLFHHYVRQDGVLGRMWRAS
>NC_010511.1|WP_012330471.1|577358_580481_-|double-strand-break-repair-protein-AddB
MSAARIFTIPPGAPFLATLADALLDGTLVGPVAQGPLGLAAVTLFLPTRRATRALAAELAARCGPAVLLPRMTPLGEADEAELDLAALAPGECPEAVAHPPIPALERRLILARLVQAWAAGIDRRLLPMGEEVPFRVPSSPADAVGLAADLEGLMDALTVEGLPWDEIGRAVEAEYSQYFSLTLDFVRIAAEHWPAILAERGVSDPVARGRALVLAEAARLRRERPADPIVVAGSTGSIPATAALIGAIAAMPRGAVVLPGLDLALDEEGWAAIETGEAVAHGHPQAILHRLLRGLDCPRAAVRPLGAPGPAARARAELLSQALRPAETTDAWADLDPGAREALARAGGAGLALVEAADEREEALAIAVALREALERPDCRAALITPDRGLARRVAAELGRWEIVAEDTAGQPLALSLAGRLARLATDVAALDAKPERVLALLAHPMVRLGLARPALERAAAALEIGVLRGPAPAKGFAGLAEALRVARGGERPHAPRPVRRLTQADWEAAADLVARLDRAFRDFAPRDFAPDQEEGVRDLVALAQAHRETCDLLLDGPDAPQDEPSVAVLDGLFDDLALAQAGMLEGRFSDYPAFFTALARERVVSARAERPHPRLRILGLLEARLLRVDRVVLGGLDEGVWPPKAETDAFLNRPMRAAVGLSSPERRLGQTAHDLVQALGCPDAVITRAHKREGSPTVPSRFLQRLRAFMGEAAWSGCLAAGGRLRALAASLDRGTEPLPPRPARPAPRPDPALFPRALSVTEVETLVRDPYGIFARHVLGLDPLEPVAVQPSASDRGTIVHDVLGGFAQRFPEALPADPRLPLYDLAVNAFAPIADAYPELYAEWWPRFERMAASFLAWEVERRPGLRRVHAEISGRWRIPIGPAEDFTLRARADRIEARRDGGHVIVDFKTGQPPSAREVFAGFAPQLTLEAAMLQAGGFRDLGPGTGAPELLYVRASGGKVPLDPVPLKPPRGEARSVEELIDEHARRFQGLVARFLRGEAAYLSRPYPKYARAFSPYDHLARVKEWSLVEGEGA
>NC_010511.1|WP_012330472.1|580477_581215_-|nucleotidyltransferase-family-protein
MPHTSAITRAFVLAAGLGKRMRPITATMPKPLVEVAGRALVDHALDRLAEAGIAEVVVNVHYLADLMEAHLRRRNGPPRIVLSDERDRLLETGGGVRKALPLLGEAPFLILNSDSFWLEGPRPNLARMVAAFDPEAMDMLLLVASAATSLGYDGLGDFQMDKAGRLARRAEREVAPFVYAGVAVVGPSFFADTPEGPFSLNLLFDRAVARERLHGLRLDGQWLHVGTPEALQAAEERVRASAVQP
>NC_010511.1|WP_012330473.1|581251_582796_-|bifunctional-tRNA-(adenosine(37)-N6)-threonylcarbamoyltransferase-complex-ATPase-subunit-type-1-TsaE/phosphotransferase
MDREAMDARTPWEIVLPDESATEDLGRFLAELLQPGDLVALSGGLGGGKTTLARALIRELTGEPDLDVPSPTFTLIQPYEGRGGVAVVHADLYRLRGPDELVELGFDELTERAITLVEWPDRLPPRSGPTLALDLALKPEFGDTARLARLIGGGGMAERLQRARALRALLDRSGWGEATRTPMQGDASSRAYERLTQPDGTTAILMISPPRADGPPVRDGKPYSAIVHLAESVHAFVAVDRGLRALGLSAPKILGQDLEAGLLILEDLGTEPVADASGPRPERYAEAVKVLARLHGTALPAVLPVAEGSDHTLPPYDLDALLFETELLIDWYAPHHARTPLSGAQRAAFTAAWTEALTGLPPERPTWVLRDYHSPNLIWLPGRDGLERIGLIDFQDAVLGHPAYDVASLLQDARVDASAEFELRLLGLYARERKLREPDFDVQGFAHAYAVLGAQRATKILGIFTRLDRRDGKPGYLAHVPRIEGYLNRNLAHPALAGVRAWYEACLPGLVPAA
>NC_010511.1|WP_012330474.1|583262_584426_-|N-acetylglucosamine-6-phosphate-deacetylase
MSSPGLALAAPRVFDGEAELGPRTLVIRDGRIEDLAAEPPPGLPCTILPPGTILAPGFVDLQVNGGGGALLNDAPTPGTLARIAAAHRRGGTTSLLPTLISDHRPVIRAAVAAVAEAIAAGMPGILGIHLEGPFLSPRRPGIHDPARLAAFAPGDVDLLTGLGARGVTLVTLAPEVAPPGTVAALVARGARVSAGHTADDGTAFRRALAEGLTGATHLFNAMSQLTAREEGAVGVALVDDRVFAGIIADGHHVGDTALVLALRLKGPGRLMLVTDAMPPVGDPRPEAGFTLFGRAIACRGDRLTGPDGTLAGSALTMAGAVRHMVRRGGASLAEALTMASLTPARWIGRDDRIGRIAPGLAADLVVLDRDLVVWGTCVRGEFARAAA

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Crispr_ID: NC_010511_5

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_010511_5

640831-640928

Orphan

Consensus_repeat	Method
TTCTGCTACAATCGGCGAACCGG	CRISPRCasFinder

1 spacers

The CRISPR arrays of NC_010511_5

>merge|NC_010511|5|640831-640928|CRISPRCasFinder
TTCTGCTACAATCGGCGAACCGGGCGATTCCTCCATTGGGGATCCTGTCAACGTCGCGCATACCGCCCGCGAGTGTTCTGCTACAATCGGCAAACCGG

>NC_010511|5|5|640831-640928|CRISPRCasFinder
TTCTGCTACAATCGGCGAACCGG	GCGATTCCTCCATTGGGGATCCTGTCAACGTCGCGCATACCGCCCGCGAGTG
TTCTGCTACAATCGGCAAACCGG

Protein	Signature genes	Signature genes Name	Protein_function
NC_010511.1\|WP_050777538.1\|652763_653618_-\|branched-chain-amino-acid-ABC-transporter-permease	unknown	unknown	gnl\|CDD\|119324
NC_010511.1\|WP_012330516.1\|637213_637972_-\|bacteriorhodopsin	unknown	unknown	gnl\|CDD\|320368
NC_010511.1\|WP_012330521.1\|646714_647227_+\|heme-binding-protein	unknown	unknown	gnl\|CDD\|377163
NC_010511.1\|WP_012330517.1\|638436_639255_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|236090
NC_010511.1\|WP_043700753.1\|649682_650126_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|369337
NC_010511.1\|WP_012330520.1\|645260_645539_-\|hypothetical-protein	unknown	unknown	unknown
NC_010511.1\|WP_012330526.1\|651739_652753_-\|branched-chain-amino-acid-ABC-transporter-permease	unknown	unknown	gnl\|CDD\|119323
NC_010511.1\|WP_012330528.1\|653670_654912_-\|ABC-transporter-substrate-binding-protein	unknown	unknown	gnl\|CDD\|380553
NC_010511.1\|WP_150108793.1\|636278_637133_-\|beta-carotene-15,15'-dioxygenase,-Brp/Blh-family	unknown	unknown	gnl\|CDD\|274766
NC_010511.1\|WP_012330511.1\|631607_631853_-\|hypothetical-protein	unknown	unknown	unknown
NC_010511.1\|WP_012330514.1\|635880_636141_-\|hypothetical-protein	unknown	unknown	unknown
NC_010511.1\|WP_012330513.1\|633625_635554_-\|adenylate/guanylate-cyclase-domain-containing-protein	unknown	unknown	gnl\|CDD\|227903
NC_010511.1\|WP_012330518.1\|639371_640223_+\|DUF1206-domain-containing-protein	unknown	unknown	gnl\|CDD\|377695
NC_010511.1\|WP_012330519.1\|641717_644888_+\|tetratricopeptide-repeat-protein	unknown	unknown	gnl\|CDD\|274350
NC_010511.1\|WP_012330522.1\|647369_649451_-\|flagellin-hook-protein	unknown	unknown	gnl\|CDD\|171664
NC_010511.1\|WP_012330525.1\|650969_651752_-\|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|213186
NC_010511.1\|WP_012330510.1\|630805_631600_+\|alpha/beta-fold-hydrolase	unknown	unknown	gnl\|CDD\|131480
NC_010511.1\|WP_012330524.1\|650272_650977_-\|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|213191
NC_010511.1\|WP_012330512.1\|632029_633298_+\|adenylate/guanylate-cyclase-domain-containing-protein	unknown	unknown	gnl\|CDD\|143636
NC_010511.1\|WP_043700749.1\|630034_630667_-\|GntR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|224715

Protein	Function_ID	Function_description	E-value
NC_010511.1\|WP_050777538.1\|652763_653618_-\|branched-chain-amino-acid-ABC-transporter-permease	gnl\|CDD\|119324	cd06582, TM_PBP1_LivH_like, Transmembrane subunit (TM) of Escherichia coli LivH and related proteins. LivH is one of two TMs of the E. coli LIV-1/LS transporter, a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of branched-chain amino acids (AAs). These types of transporters generally bind type 1 PBPs. PBP-dependent ABC transporters consist of a PBP, two TMs, and two cytoplasmic ABCs, and are mainly involved in importing solutes from the environment. The solute is captured by the PBP, which delivers it to a gated translocation pathway formed by the two TMs. The two ABCs bind and hydrolyze ATP and drive the transport reaction. E. coli LivH forms a heterodimer with another TM, LivM, to generate the transmembrane pore. LivM is not included in this subgroup. The LIV-1/LS transporter is comprised of two TMs (LivM and LivH), two ABCs (LivG and LivF), and one of two alternative PBPs, LivJ (LIV-BP) or LivK (LS-BP). In addition to transporting branched-chain AAs including leucine, isoleucine and valine, the E. coli LIV-1/LS transporter is involved in the uptake of the aromatic AA, phenylalanine.	3.09159e-63
NC_010511.1\|WP_012330516.1\|637213_637972_-\|bacteriorhodopsin	gnl\|CDD\|320368	cd15240, 7tm_ASR-like, Anabaena sensory rhodopsin and similar proteins, member of the seven-transmembrane GPCR superfamily. This subgroup includes eubacterial sensory rhodopsin from the freshwater cyanobacterium Anabaena and its closely related proteins. Unlike other sensory rhodopsins (SRI and SRII), the Anabaena sensory rhodopsin (ASR) activates a soluble transducer protein (ASRT), which may leading to transcriptional control of several genes. Although ASRT was shown to interact with DNA in vitro, the exact mechanism of photosensory transduction is not clearly understood. Moreover, the regulation of CRP (cAMP receptor protein) expression by ASR has been reported demonstrating a direct interaction of the C-terminal region of ASR with DNA, suggesting that ASR itself may also work as a transcription factor. ASR belongs to the microbial rhodopsin family, also known as type I rhodopsins, comprising the light-driven inward chloride pump halorhodopsin (HR), the outward proton pump bacteriorhodopsin (BR), the light-gated cation channel channelrhodopsin (ChR), the light-sensor activating transmembrane transducer protein sensory rhodopsin II (SRII), and the other light-driven proton pumps such as blue-light absorbing and green-light absorbing proteorhodopsins, among others. Microbial rhodopsins have been found in various single-celled microorganisms from all three domains of life, including halophile archaea, gamma-proteobacteria, cyanobacteria, fungi, and green algae. While microbial (type 1) and animal (type 2) rhodopsins have no sequence similarity with each other, they share a common architecture consisting of seven-transmembrane alpha-helices (TM) connected by extracellular loops and intracellular loops. Both types of rhodopsins consist of opsin and a covalently attached retinal (the aldehyde of vitamin A), a photoreactive chromophore, via a protonated Schiff base linkage to an amino group of lysine in the middle of the seventh transmembrane helix (TM7). Upon the absorption of light, microbial rhodopsins undergo light-induced photoisomerization of all-trans retinal into the 13-cis isomer, whereas the photoisomerization of 11-cis retinal to all-trans isomer occurs in the animal rhodopsins. While animal visual rhodopsins are activated by light to catalyze GDP/GTP exchange in the alpha subunit of the retinal G protein transducin (Gt), microbial rhodopsins do not activate G proteins, but instead can function as light-dependent ion pumps, cation channels, and sensors.	1.61057e-108
NC_010511.1\|WP_012330519.1\|641717_644888_+\|tetratricopeptide-repeat-protein	gnl\|CDD\|274350	TIGR02917, TPR_domain_protein, putative PEP-CTERM system TPR-repeat lipoprotein. This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.	7.87446e-53
NC_010511.1\|WP_012330517.1\|638436_639255_+\|hypothetical-protein	gnl\|CDD\|236090	PRK07764, PRK07764, DNA polymerase III subunits gamma and tau; Validated.	1.27942e-10
NC_010511.1\|WP_043700753.1\|649682_650126_+\|hypothetical-protein	gnl\|CDD\|369337	pfam07378, FlbT, Flagellar protein FlbT. This family consists of several FlbT proteins. FlbT is a post-transcriptional regulator of flagellin. FlbT is associated with the 5' untranslated region (UTR) of fljK (25 kDa flagellin) mRNA and that this association requires a predicted loop structure in the transcript. Mutations within this loop abolish FlbT association and result in increased mRNA stability. It is therefore thought that FlbT promotes the degradation of flagellin mRNA by associating with the 5' UTR.	2.70356e-32
NC_010511.1\|WP_012330522.1\|647369_649451_-\|flagellin-hook-protein	gnl\|CDD\|171664	PRK12688, PRK12688, flagellin; Reviewed.	1.87378e-70
NC_010511.1\|WP_012330528.1\|653670_654912_-\|ABC-transporter-substrate-binding-protein	gnl\|CDD\|380553	cd06330, PBP1_As_SBP-like, periplasmic substrate-binding domain of active transport proteins. Periplasmic substrate-binding domain of active transport proteins found in bacteria and Archaea that is predicted to be involved in the efflux of toxic compounds. Members of this subgroup include proteins from Herminiimonas arsenicoxydans, which is resistant to arsenic (As) and various heavy metals such as cadmium and zinc. Moreover, they show significant sequence similarity to the cluster of AmiC and active transport systems for short-chain amides and urea (FmdDEF), and thus are likely to exhibit a ligand-binding mode similar to that of the amide sensor protein AmiC from Pseudomonas aeruginosa.	6.10109e-79
NC_010511.1\|WP_150108793.1\|636278_637133_-\|beta-carotene-15,15'-dioxygenase,-Brp/Blh-family	gnl\|CDD\|274766	TIGR03753, hypothetical_protein, beta-carotene 15,15'-monooxygenase, Brp/Blh family. This integral membrane protein family includes Brp (bacterio-opsin related protein) and Blh (Brp-like protein). Bacteriorhodopsin is a light-driven proton pump with a covalently bound retinal cofactor that appears to be derived beta-carotene. Blh has been shown to cleave beta-carotene to product two all-trans retinal molecules. Mammalian enzymes with similar enzymatic function are not multiple membrane spanning proteins and are not homologous.	5.21979e-65
NC_010511.1\|WP_012330513.1\|633625_635554_-\|adenylate/guanylate-cyclase-domain-containing-protein	gnl\|CDD\|227903	COG5616, COG5616, Predicted integral membrane protein [Function unknown].	4.09375e-47
NC_010511.1\|WP_012330518.1\|639371_640223_+\|DUF1206-domain-containing-protein	gnl\|CDD\|377695	pfam06724, DUF1206, Domain of Unknown Function (DUF1206). This region consists of two a pair of transmembrane helices and occurs three times in each of the family member proteins.	3.66602e-12
NC_010511.1\|WP_012330521.1\|646714_647227_+\|heme-binding-protein	gnl\|CDD\|377163	pfam03928, Haem_degrading, Haem-degrading. Haem_bdg is a bacterial protein that is up-regulated in response to haemin- and peroxide-based oxidative stress. It interacts with the SenS/SenR two-component signal transduction system. Iron binds to surface-exposed lysine residues of an octomeric assembly of the protein.	5.69788e-32
NC_010511.1\|WP_012330526.1\|651739_652753_-\|branched-chain-amino-acid-ABC-transporter-permease	gnl\|CDD\|119323	cd06581, TM_PBP1_LivM_like, Transmembrane subunit (TM) of Escherichia coli LivM and related proteins. LivM is one of two TMs of the E. coli LIV-1/LS transporter, a Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporter involved in the uptake of branched-chain amino acids (AAs). These types of transporters generally bind type 1 PBPs. PBP-dependent ABC transporters consist of a PBP, two TMs, and two cytoplasmic ABCs, and are mainly involved in importing solutes from the environment. The solute is captured by the PBP, which delivers it to a gated translocation pathway formed by the two TMs. The two ABCs bind and hydrolyze ATP and drive the transport reaction. E. coli LivM forms a heterodimer with another TM, LivH, to generate the transmembrane pore. LivH is not included in this subgroup. The LIV-1/LS transporter is comprised of two TMs (LivM and LivH), two ABCs (LivG and LivF), and one of two alternative PBPs, LivJ (LIV-BP) or LivK (LS-BP). In addition to transporting branched-chain AAs including leucine, isoleucine and valine, the E. coli LIV-1/LS transporter is involved in the uptake of the aromatic AA, phenylalanine.	4.08295e-71
NC_010511.1\|WP_012330525.1\|650969_651752_-\|ABC-transporter-ATP-binding-protein	gnl\|CDD\|213186	cd03219, ABC_Mj1267_LivG_branched, ATP-binding cassette component of branched chain amino acids transport system. The Mj1267/LivG ABC transporter subfamily is involved in the transport of the hydrophobic amino acids leucine, isoleucine and valine. MJ1267 is a branched-chain amino acid transporter with 29% similarity to both the LivF and LivG components of the E. coli branched-chain amino acid transporter. MJ1267 contains an insertion from residues 114 to 123 characteristic of LivG (Leucine-Isoleucine-Valine) homologs. The branched-chain amino acid transporter from E. coli comprises a heterodimer of ABCs (LivF and LivG), a heterodimer of six-helix TM domains (LivM and LivH), and one of two alternative soluble periplasmic substrate binding proteins (LivK or LivJ).	4.21383e-113
NC_010511.1\|WP_012330510.1\|630805_631600_+\|alpha/beta-fold-hydrolase	gnl\|CDD\|131480	TIGR02427, b-ketoadipate_enol-lactone_hydrolase, 3-oxoadipate enol-lactonase. Members of this family are 3-oxoadipate enol-lactonase. Note that the substrate is known as 3-oxoadipate enol-lactone, 2-oxo-2,3-dihydrofuran-5-acetate, 4,5-Dihydro-5-oxofuran-2-acetate, and 5-oxo-4,5-dihydrofuran-2-acetate. The enzyme the catalyzes the fourth step in the protocatechuate degradation to beta-ketoadipate and then to succinyl-CoA and acetyl-CoA. 4-hydroxybenzoate, 3-hydroxybenzoate, and vanillate all can be converted in one step to protocatechuate. This enzyme also acts in catechol degradation. In genomes that catabolize both catechol and protocatechuate, two forms of this enzyme may be found. All members of the seed alignment for this model were chosen from within protocatechuate degradation operons of at least three genes of the pathway, from genomes with the complete pathway through beta-ketoadipate. [Energy metabolism, Other].	2.54429e-41
NC_010511.1\|WP_012330524.1\|650272_650977_-\|ABC-transporter-ATP-binding-protein	gnl\|CDD\|213191	cd03224, ABC_TM1139_LivF_branched, ATP-binding cassette domain of branched-chain amino acid transporter. LivF (TM1139) is part of the LIV-I bacterial ABC-type two-component transport system that imports neutral, branched-chain amino acids. The E. coli branched-chain amino acid transporter comprises a heterodimer of ABC transporters (LivF and LivG), a heterodimer of six-helix TM domains (LivM and LivH), and one of two alternative soluble periplasmic substrate binding proteins (LivK or LivJ). ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules.	4.05442e-103
NC_010511.1\|WP_012330512.1\|632029_633298_+\|adenylate/guanylate-cyclase-domain-containing-protein	gnl\|CDD\|143636	cd07302, CHD, cyclase homology domain. Catalytic domains of the mononucleotidyl cyclases (MNC's), also called cyclase homology domains (CHDs), are part of the class III nucleotidyl cyclases. This class includes eukaryotic and prokaryotic adenylate cyclases (AC's) and guanylate cyclases (GC's). They seem to share a common catalytic mechanism in their requirement for two magnesium ions to bind the polyphosphate moiety of the nucleotide.	1.73866e-58
NC_010511.1\|WP_043700749.1\|630034_630667_-\|GntR-family-transcriptional-regulator	gnl\|CDD\|224715	COG1802, GntR, Transcriptional regulators [Transcription].	1.05387e-40

>NC_010511.1|WP_012330518.1|639371_640223_+|DUF1206-domain-containing-protein
MHRVGTHALALLARFGYAARGVVSCLVGGLAVLAALGSGGQAGGSRSALATLLDQPFGRLWLGLIAVGLLGFAVWRVVEAATDADHLGRSAKALAKRAGHVVSGVVYGGLAASAAQLALGRRRGGGDDQAARDWTAWVLEKPLGQWAVGSAGLLLIGVGLALVVKGWKGDVLQRLAPPETVRRWAVPLGRLGFAARGVVFVLIGGFLVLAAVQSRSSDVKGLGGALHVLQRQPYGWALLAVTALGLTAFGLFGLVQARYRRIDPPDMSEAKAAVGGIVSRATR
>NC_010511.1|WP_012330517.1|638436_639255_+|hypothetical-protein
MLGRWLVPAITSAWVGSSPALAEMRILAAKITAGELWVLGSVDEPDDEITLDQHFRTRADASGRFEFHVTYHPATCIVMLQTKRQGRRAVVGDCGQRGAAGEPGPQGAPGPRGETGAAGQAAAVGTAGPAGPPGPVGPAGPAGPPGEVGAAGPPGPRGETGAAGPAGPPGPPGSPGPPGSPGPKGDRGEPGPRGPAGEPGPEGPSGPPGGRGAMGPPGKVGPRGPAGPPGPRGPAGSPAAAPRRPPASARPAERREPLPIQPAPAPETQPPY
>NC_010511.1|WP_012330516.1|637213_637972_-|bacteriorhodopsin
MTVQTWLWLTLFAMSLGAAAILFTAKRRTPEEETDGILHGIVPLIAAASYLAMACGQGAIRLPLGADPAAQWDFYFARYIDWTFTTPILLYALATDAMHSGMRRHGAVFGMLAADVLMIATALFFGASATAWIKWTWYAVSCGAFLGVYYVIWVPLLEESRREREDVRAAFRRNAAFLSVVWLIYPLVLIVGTDGLKLVSPVLTTALIAVLDVVAKVVFGLMAVGERARIVDRDLHETRPVRRSAPSLAPAE
>NC_010511.1|WP_150108793.1|636278_637133_-|beta-carotene-15,15'-dioxygenase,-Brp/Blh-family
MLAIAFALTGALPVPTRWEGVTALVLLFGVPHGALDGEIARPLLRPRFGRLWFPAFALPYLGLSALVLACWRVAPLATLAGFFALSVWHFGSEDAGPGRPIEALVRGGLPIAVPSLLHPDGVARLFSAVTGVPLGESPTWLGASSWLWVALACGWVLRGCAERRRATAAEMAGLVAAFAVLPPLSAFGLYFVCVHAPRHVRELVRDGRAPRVRSLREATVRALPVTLLTFAIGAALWPLYPGPAPERLVALTLQGLAALTLPHMALDALTRAVRGRPSRPGREG
>NC_010511.1|WP_012330514.1|635880_636141_-|hypothetical-protein
MWTGCGTLGELYRARIVSDEQLNQAISGYLADTKPGPRVIADGVMLDIDAAVLSHGWAHLVAHDRRATEPARRSAIRTALLLAALG
>NC_010511.1|WP_012330513.1|633625_635554_-|adenylate/guanylate-cyclase-domain-containing-protein
MDKALNRRLAAILVADIVGYSRLMGADEAGTLRRLKALRRELVDPRIAAAGGRIVKTTGDGLVVEFPSPLRAVSCAVAIQKGMLTRDAGTPEDRVFRLRIGINVGDVVAEPDGDLYGDGVNVAARLEPLAEPGGICISRSVHDQVRDKLRYPFEDRGEQELRNIARPLGVFALPAAVIPSLPETDEEPGPGRAERPLRRVALASGLVALLAAGGLGWWLSAPARPPVPNPGALPAAAAVNPAPRLSLVVLPFTNLSNDPEQDFFADAITEDLTTDVSHLADSFVIARNTAFTYKGKPVDVKQIGRDLGVRYVLEGSVRRTGENVVLNAQLISAETGAHLWADRFDGERGRLGDLQVEFVARLARSLDVQLTQAESLRSLRERPTDPGASDLAMRGWAALNKPRSLASNNEAQDYFERALALDPTLPRAILGLSRALITKPSMSWSRDKDKDIKDAEDLIDKYLASYPGDAVALVVKGDVFRARRQFDSARSMYEAAIAGNRNYAMAQALKGHVSTLTGKASEAISSELQAIRLSPRDPLLNVWYYFVCHAHTHQRHWDEAITWCNKSVALSPYWLSSIDLAAAYAWQGRQAEARAAVAEILKLMPGYTVQKWANAGWSDNPVFLEEYQYVVEGLRKAGLPEN
>NC_010511.1|WP_012330512.1|632029_633298_+|adenylate/guanylate-cyclase-domain-containing-protein
MSRDAPSRSSLLSQFPAKLRLEKFDDCIEADFKEEVRKQCIDSVKLVLPVTVVLHLLMPVGATYVFPHPQVIITYHFFIALSCVAGVMMLRWKTYRKHILNLGILVWFACASAAVLALIYTENGIYYYIGAIIFTTFYAGGFIRTTFDRASICCILVFTCSNAGLFLKSFDTKAFVYVNSFLLYTIFITLATCFFVEKTERQKFKLERELRSERDRIDRILRDILPMQIYDRIKGGENHIADLNDHVTISFCDIVGFTHLASRTSPHDVIRLLNDLFSQLDDIAAKHGIEKIKTIGDAYMAAAGVGDAIHKDAHAVAGFALDARRAVLETGERHGAAIQMRFGIATGQVISGVIGVTRPVFDVWGSTVNLASRLETASPPGAITLDARTAELLDRRFRVRPSGCIALKGIGAVATFQLVHSN
>NC_010511.1|WP_012330511.1|631607_631853_-|hypothetical-protein
MAASAVGRERARARESPLRLAKPAGAGLPVTRVADTNPALAEPSRRRARSKAGWHSREPAVPRGVAVPMPGTAVEGLAGVG
>NC_010511.1|WP_012330510.1|630805_631600_+|alpha/beta-fold-hydrolase
MRVTLAGGISAEVLGDGTPLVLLHSLLSDRASFDRVREPLAARFRVVVPDLPGFGGSRPAAGGLAAVADRVAEAVRDLGGAAPILLGNGYGGFVALQLAIRHPGLAGRLVLADCGACFPEPGRQAFRTMAAVAAEKGLAALTDTAMRRLFAPAFQAANEALMAERRAAFLRTDPAVFRAACEALAGLDLRPDLAGVTVPALVLVGEEDEATPPAMARDLARGLPDARLAILPGCAHVPPLQDPALFLAAVTPFLEESPAGSRAA
>NC_010511.1|WP_043700749.1|630034_630667_-|GntR-family-transcriptional-regulator
MLLRDTIYEAIRAEILTCRVPPGAEVREQELAERFEVSRQPVREALLRLERERLVTVHPRQGYQVNPISVADARDLLQFRLVVEPACAGEAAESAPPAVLAGLDAFRELPEGGDFIAYNRAFHTALAEASGNRRMAAVTRDLIEQADRLVRVSLATIRGRDPAQLIAEHAGIIDAVQRRDARAARRRVRDHVARAERRIIPALERSAVIL
>NC_010511.1|WP_012330519.1|641717_644888_+|tetratricopeptide-repeat-protein
MRKATALVLALGLLGQASSGARALDAIGHNARGFELQNRGEHEKAIAEFNLALRLNPKLVSAYINRGFAFRNKGDYDRAIADYDHALQIDPNSVVAFNNRGDAFYHKGEYDRAIADYNRSIKLSSDKAAVYNNRGLAFFSKEEYDRAIADYNQALRLDPKYLSAALNRGDAFRSKGEYDRAIADYNQVLQIDPRSVVSYNNRGLAFQGKGEYDRAVADYNQALTLDPGYTIALINRGDVFRIKGQYDSAIENYNQALQLNPKSKIAYNNRGFVFYNKGEYDRAIADYNSALQIDPRYVVALVNRGDAFVSKGDYDRAIGDYGHALQINPNYAFAYNGRGVALQNKGEYDRAIMDYDQALRLDPKYVFAFANRGDAFRSKGEHDVAIADYNQALRLSPNYAKAYNGRGLSFQNKAQYNRAIEDYEQVIRLDPRFVAAYNNRGFALVSKGEPTLAIADYDKALLLDPKSATVYANRGRAFQDKGEYDRAIADYDQALRLNPKDAIALNNRADILRLRHEHDRAIASYDQALQLNPKYVGAYNSRGLAFQDKGEYDRAIANYDQALQLNPRYITAYINRGDAYRRKGEHARAISDYNQALQIDQNSVIAYNNRGLCFHEQGEYDRAIIDYDRALQIDPMYSTGFINRGFAFHKKGEYDRAIADYDRALQIDPRSATAYNNRGFTFQNRGEYDLAIVDYDKAILIKPDLANSYYHRGTVLRLKGDLERSVADLTEAIRLNPRYAEAYQDRGLTFHAKGEADRALADFAEAARLKPEFENDPAFLAARRVAQEGRAGQASAASVVAAVHAPPVVAPPPVSAAAPVSETRVALVIGNGAYASVASLENPTRDARAIARSLREAGFKIVHLENDLRYDDLRRALNNFSAEADQADWAVVYYAGHGIEVGGLNYIVPIDARLKTDRAVQFEAVPLDQVLSSIEGARKLRLVILDACRDNPFLQQMTRTVAWRSVGRGLAKVEPETSGTLVAFAAKHGQVALDAQDGRENSPFATALIRNIARPGIEIRKMFGIVHDDVMSGTGRKQEPFVYGALGGEDYFFNVR
>NC_010511.1|WP_012330520.1|645260_645539_-|hypothetical-protein
MFLLVFAALGGGLTTAVLMRDYGALGALLAAPLGGSACAVLAGLGLAMRRGPEAPTLPALDEQTDAMVAALREVSARSGASGTAPGERRGAA
>NC_010511.1|WP_012330521.1|646714_647227_+|heme-binding-protein
MSFLLGCIVLGCTALAPSGRAQQAVPAPAQQAIPPYGPPLSLDTARRVAEGAEAEAKRNGWPVAVAIVDSTGHLVLFEKLDNTQYGSIEVATQKAVTAINYRRPGKALQDALANGGVGLRVLTLPGISAYEGGYPLEADGKLVGAIGVSGVLPVQDDQVARAGVEAMRAR
>NC_010511.1|WP_012330522.1|647369_649451_-|flagellin-hook-protein
MSSITLSAATRQNLLSLQDTASLLATTQNRLATSKKVNTALDNPTNFFTADGLSSRSTALSSLLDSVSNGIQTIQAANTGLTKVQTLTDQLKSVAQQALASANSFSVKATSVSTALTGASAQNLLSTGATQAVSDTALSANATATAATVTAGTAYSNGVATYTAGSYTTLTASATVTLNGTAIALATGDDINAAVTKINAQSATTGVTVAASGGKLVFTGSNSGAQFTYAATGSETGLAASGTTTNGAGASSTTLTINGTTITVATGSTESQVINAINAVTSTTGVTASDNSGKIKLTGAADGSSITVQGGTGSQVGFGTTASTTAGTFSPSAATLAIAVGFKAGDNFTVNGQSVNIAAGDTLGSIAQKVSTATSGTVSASYDATNRKFTFTAADTNTAITLGNGSTATSLLSNLGFNSPTTFAAGLGAPGSSSALAGKSLTVQVGSGPSATFTFGSAAGQISTLTQLNSALAAANAQASIDTATGRISITTANDSGTDDLKITASGTGNPFNSGTSSAVIGGDGLTARNGLVSTFNNLLTQIDQLAADSGYNGVNLLAGDTLKISFNEKNTSTLSVQGSTVSYTQLGLSVLSQSDFQENSAINKVIKSINTAASSLKSQASSLGANLAVVQNRQDFTKQMINVLDTGAANLTNADLNEEAANSQALSTRNSLGISALSLANQAQQSVLQLLR
>NC_010511.1|WP_043700753.1|649682_650126_+|hypothetical-protein
MPLRLNLKPSETIYINGAIISNGDRATDIVIHNHCRLLRESEMITEAQATTPCSKIVLLLQNVHLDVDPDHALDDLARISAQILARMPEAGPYVSRIEKAIAEGQTYLALKHGRALVAHEAAQAPAARPAGAAGARRAARPAPPSGA
>NC_010511.1|WP_012330524.1|650272_650977_-|ABC-transporter-ATP-binding-protein
MLEIRGLHAWYGASHVLHGLSLEVREGEILALIGRNGAGKTTTLRAVMGLMPKVSGAVRFRGEELLGRPAHARFPLGLAYVPEDRRIVPGLTVRENLRLGLLRAPRNLAEGPAIAAIAETFPRLAERLDQIAVTMSGGEQQMLAIARAMIARPRLILLDEPSEGIMPVLVEEMGRLFASLRAGGTTLLLVEQNVEWALNLADRAVIIDQGAVVHESSAAALREDAEIQDRYCAV
>NC_010511.1|WP_012330525.1|650969_651752_-|ABC-transporter-ATP-binding-protein
MAQVSTGAGEVLLEARGLGRRFGDFVALDGVSAQFRAGRITAVIGPNGAGKSTFFNLLSGALRPTSGTLLFGGRPIAGLPQHRFAHLGIARSYQITSLFPRLTAHENLRTAMQAFAARYDLWTRRDALRDLAERADVLLEAIGLAARRDRPAASLSHGEQRALEIGVALAAAPKLLLLDEPTAGMGPEETKAMVALLRRLSEERTILLVEHKMKMILGLSERILVLHHGRLIADGTPAEIQSDAEVRRVYLGQSGGYGHA
>NC_010511.1|WP_012330526.1|651739_652753_-|branched-chain-amino-acid-ABC-transporter-permease
MTALDPAAAPGLPEAASRRSPLAAGALSRWRAPASVAALALLPLVLPSQALAVNVLIYGLYATGYNLLYGYTGLLSFGHAAFFGTGAYATGIAIGAFGLHPLAAMALGIVLAGLLALAIGALSIRSRGIYFAMVTLALAQLVYYAALQASGWTGGENGLRGFTVARIGLGPVGLDILDPATKYAFVLACVAAALAAMSRILASPFGAVIEAIRENEARARACGFDVERTKLLAFVLSGLFCGLAGALSALHLSIVPLDSLAYPLSGTAVVMTLVGGAGTFFGPFLGALAVLVLEDSLSLWTSHWQLALGVVFILFVLFLPRGLGGAALALGRLAWRR
>NC_010511.1|WP_050777538.1|652763_653618_-|branched-chain-amino-acid-ABC-transporter-permease
MQLFSGVALGAVFVMLALGLSIIFGMLGIVNFAHGNFFMIGAYAGVFVLERTGSFWLALLLGPLLVGALGLVVERLLIRPLAGRSPDDALLLTFGLGYVLVEGVRILFGSDGLPVATPEALSGVADLGIGLFPVYRLFVIGVVALVLLLLWWALERTRLGLIVRAGARDPEILRVLGVDIQRLWLWVFGLGIALAALGGVLAAPMRSVNPEMGSAVLSEAFAVTVIGGMGSLLGSVAAGLLVGIVVSLTALVAPEMANIAVFAFMALVLLARPHGLFGKPGLGT
>NC_010511.1|WP_012330528.1|653670_654912_-|ABC-transporter-substrate-binding-protein
MGGFLAGGAAPTRRAVIGGGLALGALAGLGRPARAAEPIRIGFPVPITGPFGAEAKDQVRSAELAVRQFNEAGGLGGRMAELLVRDDKLNPGEAATRTLELIEKDRAHFIVGALSSAVQLSVNEITRSRKVLYVSISQSDTINEAKDFGRTTFHEALNPHMTTAAVAKHAFRKGSRIAYLAADYAYGHEMLRGFKRAAAAIGAETAGEILHPFGAPDYSTFMPRLRTMRPDILCICNFGRDQANAIKQANDFGMKRASRLVVPVLLHNQRLAAGPDAFEGVVGAANYFWRLEETVPSARAFNDAFRAAHGGAVPTDYGAYAYTAVRALLMAVTKAGGTDTEAVVTALEGLTYDVAKGPEHYRACDHQAVQSVLVLESKKKSEMAGEADLFTILAIEPGSEAALRSCEELGHRA

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Crispr_ID: NC_010511_6

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_010511_6

725565-725658

Orphan

Consensus_repeat	Method
CCGGCGCCTCCGGCTACACGCCCGGCCACGA	CRISPRCasFinder

1 spacers

The CRISPR arrays of NC_010511_6

>merge|NC_010511|6|725565-725658|CRISPRCasFinder
CCGGCGCCTCCGGCTACACGCCCGGCCACGAGATGAAGACGACCGGCAGCGTCAAGGGCACCTCCGGCGCCTCCGGCTACGCGCCCGGCCACGA

>NC_010511|6|6|725565-725658|CRISPRCasFinder
CCGGCGCCTCCGGCTACACGCCCGGCCACGA	GATGAAGACGACCGGCAGCGTCAAGGGCACCT
CCGGCGCCTCCGGCTACGCGCCCGGCCACGA

Protein	Signature genes	Signature genes Name	Protein_function
NC_010511.1\|WP_012330610.1\|734253_734817_+\|ribosome-recycling-factor	unknown	unknown	gnl\|CDD\|178850
NC_010511.1\|WP_012330598.1\|724064_724475_-\|DUF2000-family-protein	unknown	unknown	gnl\|CDD\|378176
NC_010511.1\|WP_012330601.1\|725708_726461_-\|sigma-70-family-RNA-polymerase-sigma-factor	unknown	unknown	gnl\|CDD\|139056
NC_010511.1\|WP_012330595.1\|720458_721355_-\|NAD(P)H-binding-protein	unknown	unknown	gnl\|CDD\|187578
NC_010511.1\|WP_150108794.1\|726817_727204_+\|VrrB-protein	unknown	unknown	gnl\|CDD\|235899
NC_010511.1\|WP_012330605.1\|728842_729343_-\|YjbQ-family-protein	unknown	unknown	gnl\|CDD\|376651
NC_010511.1\|WP_012330596.1\|721462_721936_+\|helix-turn-helix-transcriptional-regulator	unknown	unknown	gnl\|CDD\|224647
NC_010511.1\|WP_012330603.1\|727242_727908_-\|response-regulator-transcription-factor	unknown	unknown	gnl\|CDD\|225107
NC_010511.1\|WP_012330590.1\|715823_716711_+\|NAD(P)-dependent-oxidoreductase	unknown	unknown	gnl\|CDD\|223528
NC_010511.1\|WP_012330606.1\|729339_731046_-\|cisplatin-damage-response-ATP-dependent-DNA-ligase	unknown	unknown	gnl\|CDD\|274993
NC_010511.1\|WP_012330591.1\|716700_717687_-\|aldo/keto-reductase	unknown	unknown	gnl\|CDD\|381302
NC_010511.1\|WP_012330592.1\|717803_718400_+\|metallophosphoesterase	unknown	unknown	gnl\|CDD\|277336
NC_010511.1\|WP_012330608.1\|732299_733292_+\|methyltransferase-domain-containing-protein	unknown	unknown	gnl\|CDD\|227310
NC_010511.1\|WP_012330609.1\|733395_734118_+\|UMP-kinase	unknown	unknown	gnl\|CDD\|239787
NC_010511.1\|WP_012330604.1\|728133_728781_-\|DedA-family-protein	unknown	unknown	gnl\|CDD\|223659
NC_010511.1\|WP_012330607.1\|731042_732140_-\|ligase-associated-DNA-damage-response-exonuclease	unknown	unknown	gnl\|CDD\|274995
NC_010511.1\|WP_012330597.1\|722244_723930_+\|HAMP-domain-containing-protein	unknown	unknown	gnl\|CDD\|223910
NC_010511.1\|WP_050777461.1\|724473_725364_+\|AraC-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|225117
NC_010511.1\|WP_012330594.1\|718744_720487_+\|SulP-family-inorganic-anion-transporter	unknown	unknown	gnl\|CDD\|223732
NC_010511.1\|WP_012330593.1\|718454_718712_+\|helix-turn-helix-transcriptional-regulator	unknown	unknown	gnl\|CDD\|376540

Protein	Function_ID	Function_description	E-value
NC_010511.1\|WP_012330610.1\|734253_734817_+\|ribosome-recycling-factor	gnl\|CDD\|178850	PRK00083, frr, ribosome recycling factor; Reviewed.	1.3909e-107
NC_010511.1\|WP_012330598.1\|724064_724475_-\|DUF2000-family-protein	gnl\|CDD\|378176	pfam09391, DUF2000, Protein of unknown function (DUF2000). This is a family of proteins of unknown function. The structure of one of the proteins in this family has been shown to adopt an alpha beta fold.	3.28676e-51
NC_010511.1\|WP_012330601.1\|725708_726461_-\|sigma-70-family-RNA-polymerase-sigma-factor	gnl\|CDD\|139056	PRK12547, PRK12547, RNA polymerase sigma factor; Provisional.	2.17592e-59
NC_010511.1\|WP_012330595.1\|720458_721355_-\|NAD(P)H-binding-protein	gnl\|CDD\|187578	cd05269, TMR_SDR_a, triphenylmethane reductase (TMR)-like proteins, NMRa-like, atypical (a) SDRs. TMR is an atypical NADP-binding protein of the SDR family. It lacks the active site residues of the SDRs but has a glycine rich NAD(P)-binding motif that matches the extended SDRs. Proteins in this subgroup however, are more similar in length to the classical SDRs. TMR was identified as a reducer of triphenylmethane dyes, important environmental pollutants. This subgroup also includes Escherichia coli NADPH-dependent quinine oxidoreductase (QOR2), which catalyzes two-electron reduction of quinone; but is unlikely to play a major role in protecting against quinone cytotoxicity. Atypical SDRs are distinct from classical SDRs. Atypical SDRs include biliverdin IX beta reductase (BVR-B,aka flavin reductase), NMRa (a negative transcriptional regulator of various fungi), progesterone 5-beta-reductase like proteins, phenylcoumaran benzylic ether and pinoresinol-lariciresinol reductases, phenylpropene synthases, eugenol synthase, triphenylmethane reductase, isoflavone reductases, and others. SDRs are a functionally diverse family of oxidoreductases that have a single domain with a structurally conserved Rossmann fold, an NAD(P)(H)-binding region, and a structurally diverse C-terminal region. Sequence identity between different SDR enzymes is typically in the 15-30% range; they catalyze a wide range of activities including the metabolism of steroids, cofactors, carbohydrates, lipids, aromatic compounds, and amino acids, and act in redox sensing. Classical SDRs have an TGXXX[AG]XG cofactor binding motif and a YXXXK active site motif, with the Tyr residue of the active site motif serving as a critical catalytic residue (Tyr-151, human 15-hydroxyprostaglandin dehydrogenase numbering). In addition to the Tyr and Lys, there is often an upstream Ser and/or an Asn, contributing to the active site; while substrate binding is in the C-terminal region, which determines specificity. The standard reaction mechanism is a 4-pro-S hydride transfer and proton relay involving the conserved Tyr and Lys, a water molecule stabilized by Asn, and nicotinamide. In addition to the Rossmann fold core region typical of all SDRs, extended SDRs have a less conserved C-terminal extension of approximately 100 amino acids, and typically have a TGXXGXXG cofactor binding motif. Complex (multidomain) SDRs such as ketoreductase domains of fatty acid synthase have a GGXGXXG NAD(P)-binding motif and an altered active site motif (YXXXN). Fungal type ketoacyl reductases have a TGXXXGX(1-2)G NAD(P)-binding motif.	2.17144e-73
NC_010511.1\|WP_150108794.1\|726817_727204_+\|VrrB-protein	gnl\|CDD\|235899	PRK06975, PRK06975, bifunctional uroporphyrinogen-III synthetase/uroporphyrin-III C-methyltransferase; Reviewed.	0.00740344
NC_010511.1\|WP_012330605.1\|728842_729343_-\|YjbQ-family-protein	gnl\|CDD\|376651	pfam01894, UPF0047, Uncharacterized protein family UPF0047. This family has no known function. The alignment contains a conserved aspartate and histidine that may be functionally important.	3.04615e-50
NC_010511.1\|WP_012330596.1\|721462_721936_+\|helix-turn-helix-transcriptional-regulator	gnl\|CDD\|224647	COG1733, COG1733, Predicted transcriptional regulators [Transcription].	1.79112e-46
NC_010511.1\|WP_012330603.1\|727242_727908_-\|response-regulator-transcription-factor	gnl\|CDD\|225107	COG2197, CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription].	5.98591e-61
NC_010511.1\|WP_012330590.1\|715823_716711_+\|NAD(P)-dependent-oxidoreductase	gnl\|CDD\|223528	COG0451, WcaG, Nucleoside-diphosphate-sugar epimerases [Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism].	4.57897e-24
NC_010511.1\|WP_012330606.1\|729339_731046_-\|cisplatin-damage-response-ATP-dependent-DNA-ligase	gnl\|CDD\|274993	TIGR04120, DNA_ligase, DNA ligase, ATP-dependent, PP_1105 family. This model describes a family of ATP-dependent DNA ligases present in about 12 % of prokaryotic genomes. It occurs as part of a four-gene system with an exonuclease, a helicase and a phosphoesterase, with all four genes clustered or at least the first two and last two paired. This family resembles DNA ligase I (see TIGR00574 and pfam01068), and its presumed function may be in DNA repair, replication, or recombination.	0
NC_010511.1\|WP_012330591.1\|716700_717687_-\|aldo/keto-reductase	gnl\|CDD\|381302	cd19076, AKR_AKR13A_13D, AKR13A and AKR13D families of aldo-keto reductase (AKR). Schizosaccharomyces pombe aldo-keto reductase YakC is a founding member of aldo-keto reductase family 13 member A1 (AKR13A1). It catalyzes the reversible reduction of ketones to the respective alcohols using NADP(+) as a hydride donor. Rauvolfia serpentina PR is a founding member of aldo-keto reductase family 13 member D1 (AKR13D1). It catalyzes the NADPH-dependent reduction of the aldehyde perakine to yield the alcohol raucaffrinoline in the biosynthetic pathway of ajmaline in Rauvolfia, a key step in indole alkaloid biosynthesis. This family also includes Arabidopsis thaliana aldo-keto reductases, ALKR1-6.	0
NC_010511.1\|WP_012330592.1\|717803_718400_+\|metallophosphoesterase	gnl\|CDD\|277336	cd07390, MPP_AQ1575, Aquifex aeolicus AQ1575 and related proteins, metallophosphatase domain. This family includes bacterial and archeal proteins homologous to AQ1575, an uncharacterized Aquifex aeolicus protein. AQ1575 may play an accessory role in DNA repair, based on the close proximity of its gene to Holliday junction resolvasome genes. The domain present in members of this family belongs to the metallophosphatase (MPP) superfamily. MPPs are functionally diverse, but all share a conserved domain with an active site consisting of two metal ions (usually manganese, iron, or zinc) coordinated with octahedral geometry by a cage of histidine, aspartate, and asparagine residues. The MPP superfamily includes: Mre11/SbcD-like exonucleases, Dbr1-like RNA lariat debranching enzymes, YfcE-like phosphodiesterases, purple acid phosphatases (PAPs), YbbF-like UDP-2,3-diacylglucosamine hydrolases, and acid sphingomyelinases (ASMases). The conserved domain is a double beta-sheet sandwich with a di-metal active site made up of residues located at the C-terminal side of the sheets. This domain is thought to allow for productive metal coordination.	1.94107e-37
NC_010511.1\|WP_012330608.1\|732299_733292_+\|methyltransferase-domain-containing-protein	gnl\|CDD\|227310	COG4976, COG4976, Predicted methyltransferase (contains TPR repeat) [General function prediction only].	1.9929e-60
NC_010511.1\|WP_012330609.1\|733395_734118_+\|UMP-kinase	gnl\|CDD\|239787	cd04254, AAK_UMPK-PyrH-Ec, UMP kinase (UMPK)-Ec, the microbial/chloroplast uridine monophosphate kinase (uridylate kinase) enzyme that catalyzes UMP phosphorylation and plays a key role in pyrimidine nucleotide biosynthesis; regulation of this process is via feed-back control and via gene repression of carbamoyl phosphate synthetase (the first enzyme of the pyrimidine biosynthesis pathway). The UMP kinase of E. coli (Ec) is known to function as a homohexamer, with GTP and UTP being allosteric effectors. Like other related enzymes (carbamate kinase, aspartokinase, and N-acetylglutamate kinase) the E. coli and most bacterial and chloroplast UMPKs (this CD) have a conserved, N-terminal, lysine residue proposed to function in the catalysis of the phosphoryl group transfer, whereas most archaeal UMPKs appear to lack this residue and the Pyrococcus furiosus structure has an additional Mg ion bound to the ATP molecule which is proposed to function as the catalysis instead. Members of this CD belong to the Amino Acid Kinase Superfamily (AAK).	5.72697e-116
NC_010511.1\|WP_012330604.1\|728133_728781_-\|DedA-family-protein	gnl\|CDD\|223659	COG0586, DedA, Uncharacterized membrane-associated protein [Function unknown].	3.80911e-33
NC_010511.1\|WP_012330607.1\|731042_732140_-\|ligase-associated-DNA-damage-response-exonuclease	gnl\|CDD\|274995	TIGR04122, hypothetical_protein, putative exonuclease, DNA ligase-associated. Members of this protein family frequently are found annotated as a putative exonuclease involved in mRNA processing. This protein is found, exclusively in bacteria, associated with three other proteins: an ATP-dependent DNA ligase, a helicase, and putative phosphoesterase.	0
NC_010511.1\|WP_012330597.1\|722244_723930_+\|HAMP-domain-containing-protein	gnl\|CDD\|223910	COG0840, Tar, Methyl-accepting chemotaxis protein [Cell motility and secretion / Signal transduction mechanisms].	3.56757e-38
NC_010511.1\|WP_050777461.1\|724473_725364_+\|AraC-family-transcriptional-regulator	gnl\|CDD\|225117	COG2207, AraC, AraC-type DNA-binding domain-containing proteins [Transcription].	2.25737e-20
NC_010511.1\|WP_012330594.1\|718744_720487_+\|SulP-family-inorganic-anion-transporter	gnl\|CDD\|223732	COG0659, SUL1, Sulfate permease and related transporters (MFS superfamily) [Inorganic ion transport and metabolism].	4.67495e-148
NC_010511.1\|WP_012330593.1\|718454_718712_+\|helix-turn-helix-transcriptional-regulator	gnl\|CDD\|376540	pfam01381, HTH_3, Helix-turn-helix. This large family of DNA binding helix-turn helix proteins includes Cro and CI. Within Neisseria gonorrhoeae NGO_0477, the full protein fold incorporates a helix-turn-helix motif, but the function of this member is unlikely to be that of a DNA-binding regulator, the function of most other members, so is not necessarily characteristic of the whole family.	8.59747e-07

>NC_010511.1|WP_050777461.1|724473_725364_+|AraC-family-transcriptional-regulator
MDPELAPGRADRLEGSCGLRRPDWIRVAPEQGGIPRIEAFFTGHAYDPHRHDCYALGLTLPGVQRFDYRGAEQNSLAGNLIVIHPDEVHNGRAGAASGFRYRMAYLPPHRLRAALDGRAGSLPFLRRAVLDDGRLRAALVPLLADLDRGLEPLEADQAVADIAEALLAGDPSARRRREPAGAAAAIERARAYLDEAHREGVRAEELEALTGLDRFTLARQFRRRFGTSPYRYLTLRRLDEARALIRAGVGLAEAAAAAGFSDQSHITRLFVRAHGLSPGRWRRMLATAERFGAAGR
>NC_010511.1|WP_012330598.1|724064_724475_-|DUF2000-family-protein
MRYDTKIAIAVRDDLASWQKLNVTAFLAGGLVGAHPDLPGEPYRDGSGRVYGPLVRQPILIFAGSGEALARALARARERELPCCLYTRDLFATGNDADNRAAVARVATEDLDLVGLALHADRKAVDKVMRDMVLHP
>NC_010511.1|WP_012330597.1|722244_723930_+|HAMP-domain-containing-protein
MRTTRSLGVSGKLSAAFALLALVTLAASAACYLQFSSIEQKVGWTQHTYDVLGATTDLTAAMVDQETGIRGYIITADTKFLEPYQAGRRAYGAAFDKAKSLTSDNPAQQARLGELDRLVQAWSREIAEREIALTSEPSTRDEARASVGSGAGKAAMDRIRAKVAEIERAETDLMSVRAGEQQTSFRLGYAVTLGGVVLGLVLPGLLSLAVVRTLARPIQDLTAAMRRLAEGDRTVPVPGLARRDEVGAMAAAVEVFKRNAIEAERLAAAQAAEDEARTRRARTLDALTQSFDRAVSTLTAGLAGAASEMEATAQSMMAVADDTTRRSATVAGAAGVTSTNVQTVAAASEEMSVSIQEIVHQVTQSARIADRAVENAKRADATAKHLTETAERIGTFVSLISGIAGQTNLLALNATIEAARAGEAGRGFAVVAAEVKELANQTGKATDEIGARIGDIQGATRGMVADIQEIGRVIEEISAYAAGISAAVEEQGSAVQEITRNVQEAARGTEQVTTTMSGVRDGAGQTSAAATQVLGAARDLARQSEVLRGEVAEFLAKVRAA
>NC_010511.1|WP_012330596.1|721462_721936_+|helix-turn-helix-transcriptional-regulator
MSARADLARAFAGWRRAAQDPASQDPASQDPASQDPASPDPASCPVRDVLDRVGDKWTSLILIALAEGPRRFGALGRAVPDISKRMLTQTLRHLERDGLATRTVFPTKPPSVEYRLTPLGESLLEPLAGLVAWAEERHAAIRAARARFDAGDDAGAG
>NC_010511.1|WP_012330595.1|720458_721355_-|NAD(P)H-binding-protein
MSAHATHRLFVTGASGQLGTLVIDALLARLAPERVVAGMRRPDGEAGARLSARGVAVREADYDRPETLAAAFAGIDRLLLISSSEIGRREAQHRAVIAAARAAGIGLVAYTSVLRADTSPLALAGEHRRTEAALAESGLPCVILRNGWYTENYAASIPAALAEGALLGAAGEGPIASAARADYAEAAAAVLSAADPAGGADAPRIHELAGDGAYTLAEFAAEIARQARRPVAYRDLTEAAFKDALLGAGLPEPVAALLAQSDAAAARGALFDDGRALSRLIGRPTTPAAVTVAAALRR
>NC_010511.1|WP_012330594.1|718744_720487_+|SulP-family-inorganic-anion-transporter
MSAERSAASFADLYTPKLVTVLRERYGLADLRADALAGLTVAIVALPLSMAIAIASGVTPDRGLIAAIVGGFAVSALGGSRFQIGGPAGAFIVLVAATVEAHGVDGLLTATLLSGLILLAIGFLRLGTFIKYIPYPVTVGFTAGIAVIIFAAQVKDLLGLTLPGREPGPILPKLAALAAALPTVNGAALAVAGLSVAIILGLRRLRPHWPGFLIAACAASLLAWLAGLPVETIGSRFGGIPQMLPAPALPDLSPAKVAEMLPSALSFALLGGIESLLSAVVADSMSGRRHRSNCELVAQGAANVASALFGGLCVTGTIARTATNVRAGARGPVSGMLHAVFLLLFMLVAAPLARFIPLPALAAVLAVVAWNMAEKHAVAALLRASRGDALVLAATFGLVVFRDLTEGILVGFGLGALLFLHRMAQAVDVERRLPLVAEDAADSAVPRTPYDAGLASDPDVIVYRISGAFFFGSAAAVGAALDRLGERPRATVIDLSEVPLLDSTAAATIEAFARKAERHGASVLVAGASPPIRRMLLSHGVRPPAVRFRANVAEALTAARGPDPELPEAASVNAAALRRP
>NC_010511.1|WP_012330593.1|718454_718712_+|helix-turn-helix-transcriptional-regulator
MITAAQMRAARALLGIDQRQLAELAGVSLPTIQRMEASEGNVRGVVDTLTKVVEALNQAGVELIGDNAVSREGGRGVRLARPAPR
>NC_010511.1|WP_012330592.1|717803_718400_+|metallophosphoesterase
MATYFTANTHFGDARILRQRRRFASVEEHDETLIRHWNTVIGPGDAVWHLGDFAAGASRARCREIFARLNGVKRLVRGNHDTNRVLTLPWAEPPTESYRLNLPAADGSACRLFLAHYAHRAWPGLWRGTRHLYGHTHGTIPDTTRSCDVGVDAWDDRPVGIAALVARQRAATLVPDELRRDAGVEPGSRRDLSLNRDD
>NC_010511.1|WP_012330591.1|716700_717687_-|aldo/keto-reductase
MKMRKLGAAGPEVSALGLGCMGMSDFYAGRDEAEAVATLHRAVDLGVNFLDTADMYGVGRNEELVGRVVRERSEWIVVATKFGNVRGADGSFRGICGRPDYVRQACEASLRRLGVEVIDLYYQHRVDPDTPIEDTVGAMAALVREGKVRHLGLSEAAPDTIRRAHAVHPITALQTEYSLWSREPEEALLPLCRELGIAFVPYSPLGRGFLTGRIRSPDDLAPDDLRRNAPRFQGENFSRNLALVGAIEALAREKGCTPAQVALAWVLAQGEDIVPIPGTKRRRYLEENLGALDVALAPDDLARLAAALPPGAAAGTRYPAAGMQSVNR
>NC_010511.1|WP_012330590.1|715823_716711_+|NAD(P)-dependent-oxidoreductase
MVRIALSGAGGQIGRSLRPRLLAAGHRLRSGAGFDALEPLSAEETIAAGDLRDPEAVDRLLSGSEVLVHMAGTSVERPLPEVIENNLVALHAVYEGARRHGLRRVVFASSNHAFGMHPVEARLGAEAPFRPDGFYGLSKAWGEAMGRMYWDKHGIEGVALRIGTAQPRPTEPRHLATWLGLDDLAELVLRAVTAAVPGYLAVWGVSDNGASYWDNSGAAAIGYRPRQSADAFAREILAGADPRDPVARRFQGGSFAAMDYTPETERPDRSSGGDPAREGAVPKPDRPADPDPLTG
>NC_010511.1|WP_012330601.1|725708_726461_-|sigma-70-family-RNA-polymerase-sigma-factor
MRPDLLGPLADDEPPAAAAAASLSLRLRADGSLDGRPDLPPFLRDHLGRHLRACYAALLAEAQPEPLLALVARLDAALAAARPASSFRDELVASLPCLRGFAVSLTANVVQADDLVQETLLRAWQSQDRFAPGTNLKAWLFTILRNQFYTVARKRRREVEDADGEQAARMVALPDQEDGIELRDVWMRLSQLPTPQREALLLVAVQGLSYESAARIMQCQVGTVKSRVSRARTALAQALEGGAALGGASP
>NC_010511.1|WP_150108794.1|726817_727204_+|VrrB-protein
MLICGLAPALRPAPAAAETAAASAAAPTAWTGWHGGWRHHGWHGRHVGWHRHGWGRPYAYRTVGYYPARYGYRHHYWRHGHYGWHHRPYWRHYGWRHRHWRHYGWHHRPHWRHYGWHRHGWRHARFGY
>NC_010511.1|WP_012330603.1|727242_727908_-|response-regulator-transcription-factor
MSSETTIVVADDHPLFRGALRGAVGGILPEARIVEASGLDALTALLEREAEVDLILLDLTMPGVQGFSGLIYLRAQHPAIPVVIVSANEDPVVIRRALDFGAAGFIPKSLDIDEIGGAVRQVLAGGTWAPPDIALSASEDKETAELMRRLATLTPQQVRVLMMLSEGLLNKQIAYELSVSEATVKAHVSAILQKLGVESRTQAVIASSRIGATLKPPAGVA
>NC_010511.1|WP_012330604.1|728133_728781_-|DedA-family-protein
MLHSLLGDLSGLIAQHGLWIVALIVGLESLGLPLPGETCLVTAAVYAGATGDLSLPGLVASAAGGAVVGDSMGFWIGRRLGQPVLIRHGPRIGLTPDKIKLGQYLFLRHGGKVVFFGRFVAVLRVLAALLAGANRMAWPRFLVSNATGGLLWATVFGGGAYLFGTRIEAVSGPLGIAFLAVAVITLAWLIVTVRRNEARLLREAERALPGPVTPR
>NC_010511.1|WP_012330605.1|728842_729343_-|YjbQ-family-protein
MKRIETIAGGAVTRQVTGRLTVSTNGQGFTEITQEVAGFVRDSGIAQGLLTLFCRHTSASLTIQENADPDVRTDLLAALDRLAPRQGATLYDAELPGRGQGRMFYLHRDEGPDDMPGHIRTMLTDCCLAIPVAEQQLALGTWQGVYLIEHRDQHHRREVVLHLLGA
>NC_010511.1|WP_012330606.1|729339_731046_-|cisplatin-damage-response-ATP-dependent-DNA-ligase
MNDFAHLLDRLAYEPRRTAKLRLLQDYFSRAPDPERGTALAAMTGALTFREAKPTLIRGLVEARVDPVLFRMSYHYVGDLAETTALIWPAPAAPEPGGIGHNAPPPQVPSLSEVVEALATIGKAELPARIAAWLDVLDETGRWALIKLITGELRVGVSARLAKTAVASLGGVEPDAVEEVWHGLKPPYLPLFAWVEGRAERPESLDPAPFRPPMLSHPVDEETDFARLDPAAFAAEWKWDGIRVQLVGGRDRAGTAVARIYSRTGEDISAAFPDLAEAIRFEGALDGELLILREGRVQSFNVLQQRLNRKAVTGRLLQDFPAHVRAYDLLALDGEDLRPLPFGARRARLEAFVAGLDHGRIDLSPLVPFADWEALAAARADPAQAGAGEDADAIEGVMLKRRDSLYVPGRPKGPWWKWKREPYLVDAVMMYAQRGHGKRSSFYSDYTFGVWRDSPEGGEELVPVGKAYHGFTDEELAKLDRYVRNHTVKRFGPVREVEYGPRQGLVLEIAFEGLQRSTRHKSGVAMRFPRVNRIRWDKPPAEADRIETLERILERGEREVMPGREMAR
>NC_010511.1|WP_012330607.1|731042_732140_-|ligase-associated-DNA-damage-response-exonuclease
MARSDDLLTLTREGLYCPLGDFHVDPVRPVPRALITHGHSDHARAGHGRVLATPETLRIMAVRYGEDFCGARQEARLGEVLRLGDVAVRFAPAGHVLGSAQIVIEAAARRIVVSGDYKRAPDPTCLPFELVPCDVFITEATFGLPVFRHPDAADEVGKLLDSVRLFPERTHIVGAYSLGKAQRVMALLRAAGYDAPIHLHGALEKLTDLYKRERIPLGETPKVAAADRPKLGGAVVLCPPSAIQDLWSRKFPDPVTAFASGWMRVRARARQKGVELPLVISDHSDWDDLCRTIAETGAGEVWVTHGQEDALVHWCATRGIAARPLHMLGYGDEGEAEPAPGDAEPTRGGTQPARGGAGPAQGGAA
>NC_010511.1|WP_012330608.1|732299_733292_+|methyltransferase-domain-containing-protein
MTVPLRSSGDLLADRRYVWAEAALAEGDAAAAADLAEQVLTLVPDYVPAWLLLGRAREAQAGDDPAARERARHAFAAALDLDPDDALGARLRLAELGAQAGEAALSPAYVRALFDGYAGRFERHLVEGLGYRAPAMLRDALLATGHPLPFRRALDLGCGTGLAARALDDLVVAIEGVDLSPGMLAEARRLGRYAALHEGDLTAFLAGQPAGGADLVVAADVFVYLRALGPAFAGVARALAPGGLFAFTLQAHAGEGAVLGSDGRYAHGEALVRAEAAAAGLAILRLEAASTRRERGAEVPGWLAVLGRATHGPSAAEAAGGPAGSPALAP
>NC_010511.1|WP_012330609.1|733395_734118_+|UMP-kinase
MSETTPFRRVLVKLSGEALQAPDGYWLHPPTLAALAEDIAQTLQAGIQVALVVGGGNVIRGARVSAAGWIDRATGDSLGMIATVMNSLALETALNAAGVTARTMSAVSMPTICETYARQPALHHLDKGQVVVLAGGTGNPYFTTDTAAVLRAAELKCDAVLKATQVDGVYSADPKQDPRAVRYDRLTHDEAIARDLKVMDTAAFALARESRLALVVGSVHAPSSVTAILTGRAPATRVVP
>NC_010511.1|WP_012330610.1|734253_734817_+|ribosome-recycling-factor
MATPTFDLADIKRRMQGAVNSLKHDLGSLRTGRASPTLLDPIQVEAYGAAMPMAQVATISVPEPRLLSVAVWDRGMVSAVEKAIRESDLGLNPMTEGQTIRLRIPEMNEQRRKEMVKVAHKYAEEARVAVRHVRRDGLDLLKKLEKDGAISQDDEKRQADQVQKVTDQHIAEVDQTLAAKEKEIMQV

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Crispr_ID: NC_010511_7

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_010511_7

837084-837193

Orphan

Consensus_repeat	Method
ATGTCGGCTTCGCTCAGGCGCCGCGC	CRISPRCasFinder

1 spacers

The CRISPR arrays of NC_010511_7

>merge|NC_010511|7|837084-837193|CRISPRCasFinder
ATGTCGGCTTCGCTCAGGCGCCGCGCGGGCTTGGCATACGCCATCCGGTTGATGGCTTCGCCATCTCCGATGTCGGCCATGCGAATGTCGGCTTCGCTCAGGCGCCGCGC

>NC_010511|7|7|837084-837193|CRISPRCasFinder
ATGTCGGCTTCGCTCAGGCGCCGCGC	GGGCTTGGCATACGCCATCCGGTTGATGGCTTCGCCATCTCCGATGTCGGCCATGCGA
ATGTCGGCTTCGCTCAGGCGCCGCGC

Protein	Signature genes	Signature genes Name	Protein_function
NC_010511.1\|WP_012330705.1\|837478_837655_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|276870
NC_010511.1\|WP_168169190.1\|842547_844014_-\|S8-family-serine-peptidase	unknown	unknown	gnl\|CDD\|173803
NC_010511.1\|WP_012330711.1\|842281_842551_-\|hypothetical-protein	unknown	unknown	unknown
NC_010511.1\|WP_012330694.1\|830596_830770_-\|CsbD-family-protein	unknown	unknown	gnl\|CDD\|283241
NC_010511.1\|WP_012330715.1\|849144_849723_-\|ferritin-like-domain-containing-protein	unknown	unknown	gnl\|CDD\|153118
NC_010511.1\|WP_012330702.1\|836549_836723_-\|hypothetical-protein	unknown	unknown	unknown
NC_010511.1\|WP_012330695.1\|830906_831176_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|377558
NC_010511.1\|WP_012330701.1\|835772_836279_-\|MucR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|368446
NC_010511.1\|WP_012330709.1\|839921_841286_-\|MFS-transporter	unknown	unknown	gnl\|CDD\|273327
NC_010511.1\|WP_012330699.1\|834719_835406_-\|Crp/Fnr-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|223736
NC_010511.1\|WP_012330714.1\|848157_848619_-\|hypothetical-protein	unknown	unknown	unknown
NC_010511.1\|WP_012330706.1\|837781_837994_-\|hypothetical-protein	unknown	unknown	unknown
NC_010511.1\|WP_018262624.1\|831261_831516_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|377856
NC_010511.1\|WP_012330697.1\|832295_832823_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|377406
NC_010511.1\|WP_168169128.1\|846480_846642_-\|hypothetical-protein	unknown	unknown	unknown
NC_010511.1\|WP_012330708.1\|838751_839567_-\|hypothetical-protein	unknown	unknown	unknown
NC_010511.1\|WP_012330700.1\|835558_835756_+\|hypothetical-protein	unknown	unknown	unknown
NC_010511.1\|WP_012330696.1\|831666_831969_-\|hypothetical-protein	unknown	unknown	unknown
NC_010511.1\|WP_012330698.1\|832819_834661_+\|adenylate/guanylate-cyclase-domain-containing-protein	unknown	unknown	gnl\|CDD\|215016
NC_010511.1\|WP_012330713.1\|846793_848161_-\|DUF3618-domain-containing-protein	unknown	unknown	gnl\|CDD\|163708

Protein	Function_ID	Function_description	E-value
NC_010511.1\|WP_012330705.1\|837478_837655_-\|hypothetical-protein	gnl\|CDD\|276870	cd14905, MYSc_Myo44, class XLIV myosin, motor domain. There is little known about the function of the myosin XLIV class. Members here include cellular slime mold Polysphondylium and soil-living amoeba Dictyostelium. The catalytic (head) domain has ATPase activity and belongs to the larger group of P-loop NTPases. Myosins are actin-dependent molecular motors that play important roles in muscle contraction, cell motility, and organelle transport. The head domain is a molecular motor, which utilizes ATP hydrolysis to generate directed movement toward the plus end along actin filaments. A cyclical interaction between myosin and actin provides the driving force. Rates of ATP hydrolysis and consequently the speed of movement along actin filaments vary widely, from about 0.04 micrometer per second for myosin I to 4.5 micrometer per second for myosin II in skeletal muscle. Myosin II moves in discrete steps about 5-10 nm long and generates 1-5 piconewtons of force. Upon ATP binding, the myosin head dissociates from an actin filament. ATP hydrolysis causes the head to pivot and associate with a new actin subunit. The release of Pi causes the head to pivot and move the filament (power stroke). Release of ADP completes the cycle. CyMoBase classifications were used to confirm and identify the myosins in this hierarchy. .	0.00171237
NC_010511.1\|WP_168169190.1\|842547_844014_-\|S8-family-serine-peptidase	gnl\|CDD\|173803	cd07477, Peptidases_S8_Subtilisin_subset, Peptidase S8 family domain in Subtilisin proteins. This group is composed of many different subtilisins: Pro-TK-subtilisin, subtilisin Carlsberg, serine protease Pb92 subtilisin, and BPN subtilisins just to name a few. Pro-TK-subtilisin is a serine protease from the hyperthermophilic archaeon Thermococcus kodakaraensis and consists of a signal peptide, a propeptide, and a mature domain. TK-subtilisin is matured from pro-TK-subtilisin upon autoprocessing and degradation of the propeptide. Unlike other subtilisins though, the folding of the unprocessed form of pro-TK-subtilisin is induced by Ca2+ binding which is almost completed prior to autoprocessing. Ca2+ is required for activity unlike the bacterial subtilisins. The propeptide is not required for folding of the mature domain unlike the bacterial subtilases because of the stability produced from Ca2+ binding. Subtilisin Carlsberg is extremely similar in structure to subtilisin BPN'/Novo thought it has a 30% difference in amino acid sequence. The substrate binding regions are also similar and 2 possible Ca2+ binding sites have been identified recently. Subtilisin Carlsberg possesses the highest commercial importance as a proteolytic additive for detergents. Serine protease Pb92, the serine protease from the alkalophilic Bacillus strain PB92, also contains two calcium ions and the overall folding of the polypeptide chain closely resembles that of the subtilisins. Members of the peptidases S8 and S35 clan include endopeptidases, exopeptidases and also a tripeptidyl-peptidase. The S8 family has an Asp/His/Ser catalytic triad similar to that found in trypsin-like proteases, but do not share their three-dimensional structure and are not homologous to trypsin. The S53 family contains a catalytic triad Glu/Asp/Ser. The stability of these enzymes may be enhanced by calcium, some members have been shown to bind up to 4 ions via binding sites with different affinity. Some members of this clan contain disulfide bonds. These enzymes can be intra- and extracellular, some function at extreme temperatures and pH values.	1.40332e-47
NC_010511.1\|WP_012330694.1\|830596_830770_-\|CsbD-family-protein	gnl\|CDD\|283241	pfam05532, CsbD, CsbD-like. CsbD is a bacterial general stress response protein. It's expression is mediated by sigma-B, an alternative sigma factor. The role of CsbD in stress response is unclear.	6.34707e-10
NC_010511.1\|WP_012330715.1\|849144_849723_-\|ferritin-like-domain-containing-protein	gnl\|CDD\|153118	cd07909, YciF, YciF bacterial stress response protein, ferritin-like iron-binding domain. YciF is a bacterial protein of unknown function that is up-regulated when bacteria experience stress conditions, and is highly conserved in a broad range of bacterial species. YciF has a ferritin-like domain. Ferritin-like, diiron-carboxylate proteins participate in a range of functions including iron regulation, mono-oxygenation, and reactive radical production. These proteins are characterized by the fact that they catalyze dioxygen-dependent oxidation-hydroxylation reactions within diiron centers; one exception is manganese catalase, which catalyzes peroxide-dependent oxidation-reduction within a dimanganese center. Diiron-carboxylate proteins are further characterized by the presence of duplicate metal ligands, glutamates and histidines (ExxH) and two additional glutamates within a four-helix bundle. Outside of these conserved residues there is little obvious homology. Members include bacterioferritin, ferritin, rubrerythrin, aromatic and alkene monooxygenase hydroxylases (AAMH), ribonucleotide reductase R2 (RNRR2), acyl-ACP-desaturases (Acyl_ACP_Desat), manganese (Mn) catalases, demethoxyubiquinone hydroxylases (DMQH), DNA protecting proteins (DPS), and ubiquinol oxidases (AOX), and the aerobic cyclase system, Fe-containing subunit (ACSF).	3.97479e-60
NC_010511.1\|WP_012330713.1\|846793_848161_-\|DUF3618-domain-containing-protein	gnl\|CDD\|163708	cd08152, y4iL_like, Catalase-like heme-binding proteins similar to the uncharacterized y4iL. Catalase is a ubiquitous enzyme found in both prokaryotes and eukaryotes involved in the protection of cells from the toxic effects of peroxides. It catalyses the conversion of hydrogen peroxide to water and molecular oxygen. Several other related protein families share the catalase fold and bind to heme, but do not necessarily have catalase activity. This family contains uncharacterized proteins similar to Rhizobium sp. NGR234 y4iL, of mostly bacterial origin.	2.46688e-137
NC_010511.1\|WP_012330701.1\|835772_836279_-\|MucR-family-transcriptional-regulator	gnl\|CDD\|368446	pfam05443, ROS_MUCR, ROS/MUCR transcriptional regulator protein. This family consists of several ROS/MUCR transcriptional regulator proteins. The ros chromosomal gene is present in octopine and nopaline strains of Agrobacterium tumefaciens as well as in Rhizobium meliloti. This gene encodes a 15.5-kDa protein that specifically represses the virC and virD operons in the virulence region of the Ti plasmid and is necessary for succinoglycan production. Sinorhizobium meliloti can produce two types of acidic exopolysaccharides, succinoglycan and galactoglucan, that are interchangeable for infection of alfalfa nodules. MucR from Sinorhizobium meliloti acts as a transcriptional repressor that blocks the expression of the exp genes responsible for galactoglucan production therefore allowing the exclusive production of succinoglycan.	7.43113e-36
NC_010511.1\|WP_012330695.1\|830906_831176_+\|hypothetical-protein	gnl\|CDD\|377558	pfam05818, TraT, Enterobacterial TraT complement resistance protein. The traT gene is one of the F factor transfer genes and encodes an outer membrane protein which is involved in interactions between an Escherichia coli and its surroundings.	0.0021244
NC_010511.1\|WP_018262624.1\|831261_831516_-\|hypothetical-protein	gnl\|CDD\|377856	pfam07508, Recombinase, Recombinase. This domain is usually found associated with pfam00239 in putative integrases/recombinases of mobile genetic elements of diverse bacteria and phages.	2.26089e-06
NC_010511.1\|WP_012330697.1\|832295_832823_+\|hypothetical-protein	gnl\|CDD\|377406	pfam04773, FecR, FecR protein. FecR is involved in regulation of iron dicitrate transport. In the absence of citrate FecR inactivates FecI. FecR is probably a sensor that recognizes iron dicitrate in the periplasm.	2.39709e-07
NC_010511.1\|WP_012330699.1\|834719_835406_-\|Crp/Fnr-family-transcriptional-regulator	gnl\|CDD\|223736	COG0664, Crp, cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms].	7.59209e-45
NC_010511.1\|WP_012330709.1\|839921_841286_-\|MFS-transporter	gnl\|CDD\|273327	TIGR00895, transport_protein, benzoate transport. [Transport and binding proteins, Carbohydrates, organic alcohols, and acids].	1.12022e-104
NC_010511.1\|WP_012330698.1\|832819_834661_+\|adenylate/guanylate-cyclase-domain-containing-protein	gnl\|CDD\|215016	smart01080, CHASE2, CHASE2 is an extracellular sensory domain, which is present in various classes of transmembrane receptors that are parts of signal transduction pathways in bacteria. Specifically, CHASE2 domains are found in histidine kinases, adenylate cyclases, serine/threonine kinases and predicted diguanylate cyclases/phosphodiesterases. Environmental factors that are recognised by CHASE2 domains are not known at this time.	1.14906e-53

>NC_010511.1|WP_012330702.1|836549_836723_-|hypothetical-protein
MRKIGLFVAAFALATVAFWATMLTDPPRTQAKMPAGIDTTEITLRTPLPPGAGYDTF
>NC_010511.1|WP_012330701.1|835772_836279_-|MucR-family-transcriptional-regulator
MGADDDKVGRPDPLDLMGLASDLVSAYSRLTAEIVSTCLERSLSMAGFPAAAQPDAPPQPERPVPPVPIESTVTPEHIVSLENGKPYRSLKRHLAARGLTPEQYRAKWGLPPDYPMTAAAASGGRPAAGPDPAVPVGPRARRPKGRAGSAGRPGRGRGGSPAAPRGET
>NC_010511.1|WP_012330700.1|835558_835756_+|hypothetical-protein
MTHPLLRTETTDDDASPRPRAEAALDLDSLDGVVGGLATYYEMNGNWYIVGHDKSGKATGVVRVT
>NC_010511.1|WP_012330699.1|834719_835406_-|Crp/Fnr-family-transcriptional-regulator
MSEAHPLSRLLRANPFFSGLGEDVLQAVARLCVTRSLGAQEVLFQKNDPADALYAVRRGEIRIGTGTQEGRQLTLNLLGPGDVFGEVALLDGHPRTADAVATEPTDLFVIRRRDLLDLLAQQPRIAVALIELLCRRVRWMSERMEETTFLPVPARLARRLTALAEDYGDDIAVSQEELAEFANTTRETVNRQLQAWRHEALVELGRRRIRLRDRAALAMIAGHDRAKG
>NC_010511.1|WP_012330698.1|832819_834661_+|adenylate/guanylate-cyclase-domain-containing-protein
MTTRPRALAALAALALAGAWAGLLASLHLDGRAGLLDRIEAPLLDLRFTLAGARPAPPDVVIVALDDATVAEAGRFPLPRGTLAALVRRLSAGRPRAIGLDLLFLEPGAEGADLDLAASLREANAVVAGAALFPPEGAEGNGTDVPRASRILWPVAAIRTGTGLGLVNVSTDSGGTPRHVPLLIRSGDALLPSFALELAARAAGAAPSLAGDELRIGRAAVRPDLGLSLPLRFYGPRGTLPTLSAAAVLAGRTPPEALRDRVLVVGSTATAAGDSFATPFDPILPGVEVLATGVAHLVAGDGLVRDRRVRRVDAAAALALALAGALLPALAPPALGLALLGLAAGAWLALTQAAFAQGGLWFSATLPLAAILPVAALATAGRVVLERRRAGRLARAEQALRVFHPPALADRIAGDAGFLAAPVTQQAGIVFVDLSGFTALSERLGPAQTRGFLRAFHGIVEEEVTRAGGVVLAFMGDGAMCLFGLPDPRPDDADRALAAAFALVPRVRAWLAADPRTSGLDLRVGAHHGTVVVSRLGSDDHQHITATGDSVNVASRLMEVGKAHGAALVASEDLLAATRASPAAHAAFEAHRPVAIRGRARPLGVAFRWLKPA
>NC_010511.1|WP_012330697.1|832295_832823_+|hypothetical-protein
MTSRARQRARRIGAVLVGVCLVLPGSARSQGRGCTITPYTDPPREELSCPDGFTLSAERGSLYRLLDRNRDGRPEAAELSGRGLLVDAPARRGAFQIRTPHAIASVRGTVWAVDVTPARTSVFVRRGAVSVSRPSGPAVTLRDGDGVDVEAGTEPLAVKRWSPERAAGLLARFGR
>NC_010511.1|WP_012330696.1|831666_831969_-|hypothetical-protein
MQHDVTFRKAVVDTGSHDCDARLLFLGRRLLCVLVRLSDEVHRASDLHRRWYLEVGFGPCQPLPTRNPIFATIAEAKAWARDCVLHEPPECRDRPDARAP
>NC_010511.1|WP_018262624.1|831261_831516_-|hypothetical-protein
MQFDNHKFAGLRRSRDKGIQTSVAIRAAAAAERAALTVPVIREVQAAGAVSLNEIAGALNARGIPTARGRSWSAVQVRRVLQRA
>NC_010511.1|WP_012330695.1|830906_831176_+|hypothetical-protein
MKRFILGIALAAMAGSAAVAGEAGAAAGAAAGAAAGGPVGAAVGAGVGGVASGPDRRTVVEGRGGCSHTTVRKENDLGDSKTVHREDCD
>NC_010511.1|WP_012330694.1|830596_830770_-|CsbD-family-protein
MDKDRIEGSATNVGGKIKEGAGKLTGDEKLRSEGVADQVKGKVQNVVGGIKDAIKGR
>NC_010511.1|WP_012330705.1|837478_837655_-|hypothetical-protein
MRKIAAATAALIVLAGPVLAQGRPAGSSSGAASNAEENSKPTSNTAGGGGSGSAGGGK
>NC_010511.1|WP_012330706.1|837781_837994_-|hypothetical-protein
MANRTYTVRRESDGWGVYALQTGEPVRVNGRAQTGLPLETATELAESLRLLAAVGRESAERPAVERRPLQ
>NC_010511.1|WP_012330708.1|838751_839567_-|hypothetical-protein
MRARKFVLQALDPATGSPRVEALLRIRDLEALRAALGLADGEDPDLRAVHEVAPDALDRLGALSDPPFAPDPVFTQLDPWHGLREVPYLVHTGFELPLMLEGRKPLAVFSDLYPVDWLDELLARFDPAVSEGRIVRRLVDRPASGPRSAGEPCGLRIREAYFALPGEEWRIDAAIRLRREVSSGWTEAMERREGALLGYEDWQNDWWIAHRFRRLSGTAPADPCRGALGPADQGARPVAARRDAAGPGLAGAPSPEGGRQEKGPPEGRPEV
>NC_010511.1|WP_012330709.1|839921_841286_-|MFS-transporter
MNHGAVNVQSFLNEHPFSPFQWIIFALCFLIVLLDGFDTAAIGYIAPSLISEWGVTRPALAPVLSAALFGLAAGALAAGPLADRLGRRLVLIGAVLVFGAACLCSAFAGDLDHLVIWRFVTGLGLGAAMPNAVTLMSEYCPDARRATLTNMMFCGFPLGAAFGGFLAAWMIPQFGWRSVLVLGGVVPLLLTVLMIALLPESVRYMVARGQPSERVRAVLGRISRAAAEARAFTMTEAAPVAGEARSGVGLVLSGAYVVGSAMLWLAYFMGLVIFYALINWMPILFKDAGMDARTAALIAALFPLGGVGAIFLGWLMDRANGNLVIAAGYALTALAIWAIGLVSGVLGLLVLFVFVGGTLMNTAQSSMPALAAAFYPTQGRATGVGWMLGLGRFGGIAGSFLVAELSRRQLSFGAIFAIVAVPGLIAAAALVIKQLAHPEDRAARAAAGGEALGH
>NC_010511.1|WP_012330711.1|842281_842551_-|hypothetical-protein
MKVPTMSSVMFTFGEHTPEHLQDTLGDRIKQIPGVRSVGRISPGAKKPELRRLWYAEVLNSDAASALVAQLREQDGIVSAELPAERGLI
>NC_010511.1|WP_168169190.1|842547_844014_-|S8-family-serine-peptidase
MRRTTASIFTTQALPQHHDDILVVTMRPGPAEAPAAAGMAMGMGMAPAPETPGLGALSYFARAGRIKRVVPLRASEEAVTAPSPMAAAAAMMGFHRPAGAPDVGAPVRFIEMMDGQDAKQLHGALASDPSVLSVSQVPVRYLAARRAGRTAAGGGLGIAAAPPAASLLWNLAKIRWQEARAAAGFQEATRVRVAVLDTGVDAKHPSLRVSNYYWQNADLTRPVSELDLIGHGTHVSGTIAALIASGVSVQGVCACQLDVWKIFDDEPTYAPGQGAFVYYVNPILYRRALAACVDDPPHVVNLSIGGPAVPDPTERTLFEQLLASGVTICAAMGNDRQYGSPTSYPAAIPGVVAVGATGLDDRVTLFSNSGNHIAVAAPGKAIWSTLPRYDGQTAFGIAYGPDGRPQPGARVRRECNYDAWDGTSMATPHVTGSAALLIAKSIAAGGELKPDQVRAALMTSADKVQAMNGADFSADYGAGRINLLKLLQ
>NC_010511.1|WP_168169128.1|846480_846642_-|hypothetical-protein
MVTLVNAAVSLAAAFFLGLFAEGIDAAGGERRGNVPRGFTHWRSSTTPCASPA
>NC_010511.1|WP_012330713.1|846793_848161_-|DUF3618-domain-containing-protein
MSDATEDLEHEVEASRARLDRTLDSLQARLNVSRLAEDLVGPNAPGPALNAGARRLLDGARENLLPTLLVGAGLGFLLYDALRQEAERRRLRVVPGAPRTYARYADGLERRAADEDEVIARIIATMREEGRITRERYGRAVRTSHAKSHGLAEGTLHVLDGLPPELRQGLFAEPRTYPVIARFSHVPGEYLDDRKVSAPRGLSLKIFGVEGERLPGHEGETTQDFILDTGTTFPAADAKAFLATIGALRRATPAPVAVKQAVSAGARAANAVLNAVGLGSATLDFFGHPPYHPLAEAYYSQTPLRYGAYVAKLAVRPATEGLRALIGRTIDLSGDENALRHAVTDYLTTHPVAYEVAVQLCTDPARMPIEDASREWPEAESPYRPVARLVLPAQDSQGRIGKEEDLAFCPSHTLAAHRPLGSINRARLRAYEAMGTLRRQENGRSTAEPRTVAEI
>NC_010511.1|WP_012330714.1|848157_848619_-|hypothetical-protein
MLDDTEGLGRGPAGEGGRDETIAGRLLEEAHGYVGKRKADAVRAVSDVAAVIRGSGAGLGEAPHLKAFFDSAAEGVEALADGIAARTPGEIYDEVDAAIRRRPGIALAAAALAGFALFRLVRAAGPRPIPRSRALVPAEPLPIPDPRATEPAR
>NC_010511.1|WP_012330715.1|849144_849723_-|ferritin-like-domain-containing-protein
MAAKTKTLQDAFYETLKDVYYAERQSVRALKKSARAAENDELRQAFERHAEESAEQVERLQQVFEILGKPARGKTCEAMQGLTSEMEEDLEDFGGGPAADAVLVGCAQAVEHYEIARYGTLKTWAAQLGYRDAAKLLDETLQEEKRTDQLLTEIAGRINQEGAGDEPGGQDRGGQDGGGQGRGGQGRGGKAA

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Crispr_ID: NC_010511_8

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_010511_8

1156778-1156887

Orphan

Consensus_repeat	Method
ATGGCGAAGCAATCCGTCGGATGTCG	CRISPRCasFinder

1 spacers

DEDDh

The CRISPR arrays of NC_010511_8

>merge|NC_010511|8|1156778-1156887|CRISPRCasFinder
ATGGCGAAGCAATCCGTCGGATGTCGTATGACAAGCCCGCGCGGCGCTTGAGCGAAGCCGACATCCGCATGGCCGAAAGGGGAGATGGCGAAGCAATCCCTCGGATGTCG

>NC_010511|8|8|1156778-1156887|CRISPRCasFinder
ATGGCGAAGCAATCCGTCGGATGTCG	TATGACAAGCCCGCGCGGCGCTTGAGCGAAGCCGACATCCGCATGGCCGAAAGGGGAG
ATGGCGAAGCAATCCCTCGGATGTCG

Protein	Signature genes	Signature genes Name	Protein_function
NC_010511.1\|WP_012330989.1\|1155845_1156703_+\|alpha/beta-hydrolase	unknown	unknown	gnl\|CDD\|223669
NC_010511.1\|WP_012330979.1\|1148229_1149117_+\|amidohydrolase-family-protein	unknown	unknown	gnl\|CDD\|238636
NC_010511.1\|WP_012330990.1\|1157165_1158278_+\|bifunctional-DNA-binding-transcriptional-regulator/O6-methylguanine-DNA-methyltransferase-Ada	unknown	unknown	gnl\|CDD\|185333
NC_010511.1\|WP_012330982.1\|1150152_1150767_-\|dephospho-CoA-kinase	unknown	unknown	gnl\|CDD\|234620
NC_010511.1\|WP_012330987.1\|1154218_1155292_+\|uroporphyrinogen-decarboxylase	unknown	unknown	gnl\|CDD\|234644
NC_010511.1\|WP_012330984.1\|1151672_1152305_-\|septum-formation-inhibitor-Maf	unknown	unknown	gnl\|CDD\|167380
NC_010511.1\|WP_012330994.1\|1159958_1162391_+\|PBP1A-family-penicillin-binding-protein	unknown	unknown	gnl\|CDD\|273955
NC_010511.1\|WP_012330983.1\|1150763_1151627_-\|shikimate-dehydrogenase	unknown	unknown	gnl\|CDD\|234703
NC_010511.1\|WP_012330996.1\|1163519_1164554_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|380548
NC_010511.1\|WP_012330991.1\|1158274_1158979_+\|2OG-Fe(II)-oxygenase	unknown	unknown	gnl\|CDD\|378278
NC_010511.1\|WP_018262430.1\|1165328_1165514_+\|hypothetical-protein	unknown	unknown	unknown
NC_010511.1\|WP_150108801.1\|1158981_1159425_-\|hypothetical-protein	unknown	unknown	unknown
NC_010511.1\|WP_012330993.1\|1159604_1159952_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|236641
NC_010511.1\|WP_012330988.1\|1155406_1155832_+\|protoporphyrinogen-oxidase-HemJ	unknown	unknown	gnl\|CDD\|367596
NC_010511.1\|WP_012330997.1\|1164787_1165060_+\|DUF2312-domain-containing-protein	unknown	unknown	gnl\|CDD\|370805
NC_010511.1\|WP_012330995.1\|1162458_1163346_+\|MBL-fold-metallo-hydrolase	unknown	unknown	gnl\|CDD\|293807
NC_010511.1\|WP_012330986.1\|1152872_1153703_-\|kinase/pyrophosphorylase	unknown	unknown	gnl\|CDD\|235419
NC_010511.1\|WP_012330998.1\|1165849_1166704_+\|hydratase	unknown	unknown	gnl\|CDD\|226480
NC_010511.1\|WP_012330981.1\|1149319_1150036_-\|DNA-polymerase-III-subunit-epsilon	DEDDh	cd06127_DEDDh_CAS-I	gnl\|CDD\|235574
NC_010511.1\|WP_012330985.1\|1152435_1152711_-\|hypothetical-protein	unknown	unknown	unknown

Protein	Function_ID	Function_description	E-value
NC_010511.1\|WP_012330989.1\|1155845_1156703_+\|alpha/beta-hydrolase	gnl\|CDD\|223669	COG0596, MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [General function prediction only].	5.61909e-05
NC_010511.1\|WP_012330979.1\|1148229_1149117_+\|amidohydrolase-family-protein	gnl\|CDD\|238636	cd01311, PDC_hydrolase, 2-pyrone-4,6-dicarboxylic acid (PDC) hydrolase hydrolyzes PDC to yield 4-oxalomesaconic acid (OMA) or its tautomer, 4-carboxy-2-hydroxymuconic acid (CHM). This reaction is part of the protocatechuate (PCA) 4,5-cleavage pathway. PCA is one of the most important intermediate metabolites in the bacterial pathways for various phenolic compounds, including lignin, which is the most abundant aromatic material in nature.	5.00313e-69
NC_010511.1\|WP_012330990.1\|1157165_1158278_+\|bifunctional-DNA-binding-transcriptional-regulator/O6-methylguanine-DNA-methyltransferase-Ada	gnl\|CDD\|185333	PRK15435, PRK15435, bifunctional DNA-binding transcriptional regulator/O6-methylguanine-DNA methyltransferase Ada.	6.39093e-139
NC_010511.1\|WP_012330982.1\|1150152_1150767_-\|dephospho-CoA-kinase	gnl\|CDD\|234620	PRK00081, coaE, dephospho-CoA kinase; Reviewed.	2.84524e-84
NC_010511.1\|WP_012330987.1\|1154218_1155292_+\|uroporphyrinogen-decarboxylase	gnl\|CDD\|234644	PRK00115, hemE, uroporphyrinogen decarboxylase; Validated.	1.03499e-162
NC_010511.1\|WP_012330984.1\|1151672_1152305_-\|septum-formation-inhibitor-Maf	gnl\|CDD\|167380	PRK02478, PRK02478, Maf-like protein; Reviewed.	1.18332e-63
NC_010511.1\|WP_012330983.1\|1150763_1151627_-\|shikimate-dehydrogenase	gnl\|CDD\|234703	PRK00258, aroE, shikimate 5-dehydrogenase; Reviewed.	8.48094e-111
NC_010511.1\|WP_012330996.1\|1163519_1164554_+\|hypothetical-protein	gnl\|CDD\|380548	cd06325, PBP1_ABC_unchar_transporter, type 1 periplasmic ligand-binding domain of uncharacterized ABC-type transport systems predicted to be involved in uptake of amino acids, peptides, or inorganic ions. This group includes the type 1 periplasmic ligand-binding domain of uncharacterized ABC (ATPase Binding Cassette)-type transport systems that are predicted to be involved in the uptake of amino acids, peptides, or inorganic ions. This subgroup has high sequence similarity to members of the family of hydrophobic amino acid transporters (HAAT), such as leucine-isoleucine-valine binding protein (LIVBP); its ligand specificity has not been determined experimentally.	1.23376e-102
NC_010511.1\|WP_012330991.1\|1158274_1158979_+\|2OG-Fe(II)-oxygenase	gnl\|CDD\|378278	pfam09859, Oxygenase-NA, Oxygenase, catalyzing oxidative methylation of damaged DNA. This family of bacterial sequences is predicted to catalyze oxidative de-methylation of damaged bases in DNA.	2.73501e-117
NC_010511.1\|WP_012330994.1\|1159958_1162391_+\|PBP1A-family-penicillin-binding-protein	gnl\|CDD\|273955	TIGR02074, Includes:_Penicillin-insensitive_transglycosylase, penicillin-binding protein, 1A family. Bacterial that synthesize a cell wall of peptidoglycan (murein) generally have several transglycosylases and transpeptidases for the task. This family consists of bifunctional transglycosylase/transpeptidase penicillin-binding proteins (PBP). In the Proteobacteria, this family includes PBP 1A but not the paralogous PBP 1B (TIGR02071). This family also includes related proteins, often designated PBP 1A, from other bacterial lineages. [Cell envelope, Biosynthesis and degradation of murein sacculus and peptidoglycan].	0
NC_010511.1\|WP_012330993.1\|1159604_1159952_+\|hypothetical-protein	gnl\|CDD\|236641	PRK10019, PRK10019, nickel/cobalt efflux transporter RcnA.	0.00393987
NC_010511.1\|WP_012330988.1\|1155406_1155832_+\|protoporphyrinogen-oxidase-HemJ	gnl\|CDD\|367596	pfam03653, UPF0093, Uncharacterized protein family (UPF0093).	1.06458e-61
NC_010511.1\|WP_012330997.1\|1164787_1165060_+\|DUF2312-domain-containing-protein	gnl\|CDD\|370805	pfam10073, DUF2312, Uncharacterized protein conserved in bacteria (DUF2312). Members of this family of hypothetical bacterial proteins have no known function. Structural modelling suggests this domain may bind nucleic acids.	7.54825e-26
NC_010511.1\|WP_012330995.1\|1162458_1163346_+\|MBL-fold-metallo-hydrolase	gnl\|CDD\|293807	cd07721, yflN-like_MBL-fold, uncharacterized subgroup which includes Bacillus subtilis yflN; MBL-fold metallo hydrolase domain. This subgroup includes the uncharacterized Bacillus subtilis yflN protein. Members of this subgroup belong to the MBL-fold metallo-hydrolase superfamily which is comprised mainly of hydrolytic enzymes which carry out a variety of biological functions. The class B metal beta-lactamases (MBLs) from which this fold was named are only a small fraction of the activities which are included in this superfamily. Activities carried out by superfamily members include class B beta-lactamases, hydroxyacylglutathione hydrolases, AHL (acyl homoserine lactone) lactonases, persulfide dioxygenases, flavodiiron proteins, cleavage and polyadenylation specificity factors such as the Int9 and Int11 subunits of Integrator, Sdsa1-like and AtsA-like arylsulfatases, 5'-exonucleases human SNM1A and yeast Pso2p, ribonuclease J and ribonuclease Z, cyclic nucleotide phosphodiesterases, insecticide hydrolases, and proteins required for natural transformation competence. Classical members of the superfamily are di-, or less commonly mono-, zinc-ion-dependent hydrolases, however the diversity of biological roles is reflected in variations in the active site metallo-chemistry.	5.08136e-67
NC_010511.1\|WP_012330986.1\|1152872_1153703_-\|kinase/pyrophosphorylase	gnl\|CDD\|235419	PRK05339, PRK05339, pyruvate, phosphate dikinase/phosphoenolpyruvate synthase regulator.	7.93479e-147
NC_010511.1\|WP_012330998.1\|1165849_1166704_+\|hydratase	gnl\|CDD\|226480	COG3971, COG3971, 2-keto-4-pentenoate hydratase [Secondary metabolites biosynthesis, transport, and catabolism].	1.20331e-27
NC_010511.1\|WP_012330981.1\|1149319_1150036_-\|DNA-polymerase-III-subunit-epsilon	gnl\|CDD\|235574	PRK05711, PRK05711, DNA polymerase III subunit epsilon; Provisional.	1.87529e-108

>NC_010511.1|WP_012330989.1|1155845_1156703_+|alpha/beta-hydrolase
METRRLTLTLPDRTVSVGCDVIGSGPDALLLPALSSIATREEMRPLAERLSGRFRCLIPDWPGFGAEPRARLPLSPAALHGVLDALLAALPGPFAIGVAAGHAAPYLAAAARRHPGRFARLVLVAPTWRGPLPTAMGPERRPLYARLRRAVEAPVLGHLLYRVNLSTPVVARMMRAHVYADPARVTPAVLAAKRRVTHQPGARFGTAAFVTGALDPAATREEFLSLFGPGLPPVRVLRPEAAPRRSGAEMDALLATGLVARATVPGALAPHEEHPEAVAAAILAP
>NC_010511.1|WP_012330988.1|1155406_1155832_+|protoporphyrinogen-oxidase-HemJ
MLYLWIKAAHVVALIAWMAAMLYLPRLFVYHAGLPAGSPQGETFKVMERRLAKAIMTPAMIATWVLGLTLAWMSGAYAQGWLHAKFALVLAMSGLHGWFARMVKDFAADRNTRAPTFYRVVNEVPTLLMIGIVILAIVKPF
>NC_010511.1|WP_012330987.1|1154218_1155292_+|uroporphyrinogen-decarboxylase
MGESEREARPVLRVLSGESLSPPPAWMMRQAGRYLPEYRELRAKAGSFLDLCYTPDFATEVTLQPIRRFGFEAAILFSDILVVPHALGQGVRFVEGEGPRLDALEDPAAFGTLRGAGDARVMDHLAPVFETVSRLRAALPRETTLLGFCGAPWTVASYMIGGRGTPDLAPARALAARDPALLDGLIERLVAVSTEYLARQIEAGADAVQIFESHGGTLPGMPEGEAGDALTRWSLGPIARIVAGLRARVPGARVIVFPRGTGLDGHARTLAATGADAVGVDWDVDLAALRGRLPGRAVTQGNLHPHTLIAGGAALDAAVDAILAATAGLPHIFNLGHGITPETPIAHVERMLARLRR
>NC_010511.1|WP_012330986.1|1152872_1153703_-|kinase/pyrophosphorylase
MVRSYFHLHLVSDSTGETLINVGRAAAAQYEGVSAIEHVYPLVRSAAQLERVINEIEQAPGIVLYTLVGQDLTERLEEACRATSSPYLSVLQPVHGLLQSYLGAHSTARPGAQHMLNAEYFKRIDAMNFTLAHDDGNLPLDLDDADVILLGVSRSSKTPTSIYLANRGLKTANIPLVPGVPLPPALEAARKPLIVGLLASPERIVQIRQNRLLSLKADDSTAYVDHEAVANEVAVSRRLFAKHRWPVIDVTRRSIEETAAAIVELHREHRLRFIAE
>NC_010511.1|WP_012330985.1|1152435_1152711_-|hypothetical-protein
MTSLPPLPFAPGLRVVPASGPVLDLATVEEARRFVERERLPVVRSGIHWLDVHKRLLLAQATRREADVEAARAALAEALRRDAGGRLTLAA
>NC_010511.1|WP_012330984.1|1151672_1152305_-|septum-formation-inhibitor-Maf
MTAPPAPAPSPWRGSAPLLLASASATRRALLEAAGLPVETRASGIDERAVEAACGGLPPADLALALAEAKCAAVARDAPGRAVVGADQVLDLDGTLLHKPADLGAARAHLAALQGRSHALHSAVALALDGAVAERFVVSARLTLRPLDGAAIDAYLAAAGPAVAASVGAYQLEGLGIHLFERIEGDHATILGLPLLPLLARLRARGLLSF
>NC_010511.1|WP_012330983.1|1150763_1151627_-|shikimate-dehydrogenase
MTSLPKAFVVGHPIAHSRSPLIHGHWLAAHGLPGRYERVDVAPEAFPAFLRDFPERGFVGGNVTIPHKEAAFRGAALLTPRAERIGAVNTLSLDAAGRLHGDNTDAPGFLAHLDASLGADWPRTTGTDAGRAVLVLGAGGAARAILVGLLERGLPHLRVANRTAARAEALRALDPTRIEAVAWAHLPALTGGTGLLVNTTSLGMAGAGALDLDLSGLPPEAAVADIVYVPLETPLLAAARARGLRAVDGLGMLLHQAVPGFARWFGVTPRVTPELRALVVADLEGRR
>NC_010511.1|WP_012330982.1|1150152_1150767_-|dephospho-CoA-kinase
MTRPFILGLTGSIGMGKSATAAMFRARGVPVHDADACVHALYGPGGEAAARIGEAFPGTLAADGAVDRARLRAAVLDRPDRLGRLERLVHPLVREAEAAFLAAHAGADLVVLDVPLLFETGGEARCDAVAVVTAPAEVQRARVLARPGMTEATFAAILGKQMPDAEKRRRADALIETGEGFPRAQAQVDALIAAVRAGTLARRP
>NC_010511.1|WP_012330981.1|1149319_1150036_-|DNA-polymerase-III-subunit-epsilon
MLREIVLDTETTGTDAKTDRLVEIGGIELLNHIPTGREFHRYINPQRPVSQGALAVHGLADAFLADKPPFAAILPAFLDFCGDATFVIHNAAFDVGFLNAEYARLGDAAPPAIDLAGVVDTLALARRKHPNAANNLDALCARYGIDNSRRTKHGALLDAQILAEVYIELLGGKQTSLGLTLDVASTVRVATLGGPAAHVPRAVRSRLTQAEREAHAAFTAGLGGGAIWRDYIGEDTAG
>NC_010511.1|WP_012330979.1|1148229_1149117_+|amidohydrolase-family-protein
MPEIRDCPGPDPHPRAARRFAVPAGATDTHAHVIGLPPAYPFVAARSYTPPAATPQAYLAMLDATGMTYGVLVQVSVHGTDNRLMVETLRAHPRRLRGIAVIPLGLPDRDLAALKEAGVVGLRLNVLYGGGIGFDQVEAYGALAREMGWHLQFLIDARQLPPLADRLSRLPVPFCVDHMGHMPTGCGTQDPGFRTLVGLVRDGAFVKLSGAYRMSAQPLPYSDTVPFARALMAAAPERCVWGSDWPHVAHWDPMPNVGDLLDLLAVWVPDEPARHRVLVENPARLYGFPAVSPGG
>NC_010511.1|WP_012330990.1|1157165_1158278_+|bifunctional-DNA-binding-transcriptional-regulator/O6-methylguanine-DNA-methyltransferase-Ada
MTLPDLDPMRARPAGDPRYAALVRRDAAADGTFVYAVRTTGVYCRPSCPARTPRPENVAFYASGREAAGAGFRPCRRCRPDEAAPAARQAEAVARACRMIDEAETPPSLDALARAAGQSPFHFHRVFKRVTGVTPRAYAAARRSARLTEGLLREADSVTAAIFEAGYAASSRFYAAAPSRLGMTPTAYRRGGEGATIRFAVGPCSLGSVLVAATGKGLCAILLGDDPEALVRDLQNRFPKADLIGGDPGFEALVAQVVGLVEAPEAGRVDLPLDIIGTAFQQRVWQALRAIPAGETATYTQIARAIGEPRAVRAVAQACGANPLAVAIPCHRVVRHDGALSGYRWGVERKRTLLAREAGCREPTAPEGER
>NC_010511.1|WP_012330991.1|1158274_1158979_+|2OG-Fe(II)-oxygenase
MSPDAVGALDWPRIAADLDAHGCAAAGRLLDGPTCARLRALYDDEAPFRSRIVMARHGFGRGEYKYFAYPLPEPLAALRGALYSRLAPLANRWSATLGSALRYPPDHAAFLDQCRAAGQTRPTPLLLRYGPGDYNCLHQDLYGPQIFPLQVAILLSVPGRDFTGGEFVLTEQRPRMQSRAEVVPLAQGEAVIFAVHHRPVQGGRGAYRVALRHGVSRVRTGERCATGLIFHDAA
>NC_010511.1|WP_150108801.1|1158981_1159425_-|hypothetical-protein
MTVLVALAAPAAAQPKPKPKAPPPKEAAPPPDASAGLLFPCRSEKETCYVGVPKDGKLTVLFTNDPKGAEISGRALAVAGEGPNAPDLATNDGKVVMMVGTYDPKAGLTKAEIVDVAGPLVAFAIKASLGGGDEQPAAPPPPAPKRR
>NC_010511.1|WP_012330993.1|1159604_1159952_+|hypothetical-protein
MRARHLMLAFGLLVALCGWASASPLIPRAAVTVALDQPSTVETVRWRRHRHWRRHRHWRRHHYHRRHWHHRRHWHHRRHWHHRAHGHHRRLHGRALHFSRPAGHSWIEPRQAAGR
>NC_010511.1|WP_012330994.1|1159958_1162391_+|PBP1A-family-penicillin-binding-protein
MPEGPRGAPGRGRDWLDLGAAPAPDAPAGGTGPAPRARTGRIRAALSRLRERLAGIRGRAARAASHPAARRAAAGATAGFRAAWHPLRRAAARVPWLRVLAGSLALGLALLGVILVYALATLPVNGGLVVEPTASALVVRAEGGEAFATRGVIKGAKLAPRDVPQVLAQAIVAIEDRRFFTHRGVDLRGLLRAALRNAAAGGTREGGSTLTQQLVRMSYLSQDRTLKRKVQEAILALWLESQLPKDEILTRYLNTAYFGAGVYGADAASQRYFGKSARELTLSEAAMLAGLVRAPSQLAPHRNLDGARGRAAQVLEAMVETGAITPEQAEEARRHPATVQVPTETPVGTNYFVDMVADQAKALIGAGPADAALRTTLDLTLQNIAESVLARHLDEAGERRKVSQGAILAMSPDGAILALVGGRDYAESQFNRVTQARRQPGSLFKLFVYLTALKNGYRPDSVMVDRPTQIGEWEPENYGGRYRGAVTLRTAFAHSINTVAVQLAEAVGIPAVIETARGLGIQSDLPNLPSLALGSAETTLLDLTRAYAALAAGAESVEPYAIRQIAARDQVLYTRPAAAPTPARDQAARAGMLDLLAAVVREGTGKGARVAVPAGGKTGTTQDNRDAWFIGFTQDIVVGVWLGNDDNAPMAGVTGGDMPAAIWRDFVTQAIAVRGRAAKARAPKPERPQARPEAAAADPDAEARPERGLLRGTPSVVDTGTLDLGGQTVRLLGVEGLSGRNARELGRYLRRRDVSCTPAEAGAYRCSLDGQDLSELVLFNGGGRAGADATPDLLAAEEQARSNRIGIWRR
>NC_010511.1|WP_012330995.1|1162458_1163346_+|MBL-fold-metallo-hydrolase
MAQQIPISPEARADGPAGPDGTHAIAPDVAYQRHTLVNVVYLGPPGAGDRGWVLVDAGIPGSRGTIEKTAAARFGAGARPAAILMTHGHFDHVGALEDLAEAWDAPVYAHGLETPYLDGSAACPPPDPRVGGGLFALISPLFPTKPVDVGARLRLLPEDGSVPPLPGWRWLHTPGHSPGHVSFWRPDDRMLVAGDAFVTTAQESIYAVAVQETELHGPPRYLTIDWEAARASVEALARLRPETAVTGHGRPLKGSALREGLDALVRDFAIVAVPRDGRYVAEPARAADGSAYRPT
>NC_010511.1|WP_012330996.1|1163519_1164554_+|hypothetical-protein
MPGPFAPAIPAAARAPVRRAIRRRDLIPLCAAAAAWPLGARAERGPRRIGILVTGSPDSHGAFVAAFRRRLAELGHAEGRDVAFDLRWSEGRIERLGPLAEDLAQLAPDLVVTSTTAAALAAKRVMPERPIVSATLIDPIGAGLVTSLARPGGTVTGMLISFETLLGKQLEVAREMLPGVTRIGMLVNPANPVIPFQRENTQAYADRLRARLIPVEARSPADLDAAFATFARDSAGFVIVLLDALFITHRARIAELALASRVPTVAGARELAEAGGLVSYGIDLSATWRQAAAFADRVLRGARPADLPVELPTKYELVLNLGAASRFGITVSTMLLARADTVIE
>NC_010511.1|WP_012330997.1|1164787_1165060_+|DUF2312-domain-containing-protein
MGDTAGIPGDRIRTIIERIEKLEEEIKDLNEAKKEVFLEAKSDGLDVKILKEIIKLRKQDQDERDEHETLLDVYLRAMDAPAPVPSARAA
>NC_010511.1|WP_018262430.1|1165328_1165514_+|hypothetical-protein
MVKPSVAKELPSREAGQSHDAQEHQKSEMNDAELEHVSAGAYEFYVQTEGVKQGKAKEGVK
>NC_010511.1|WP_012330998.1|1165849_1166704_+|hydratase
MSGSERAPAEDREAPSPDAVARAVLAALDERRQIAPLGAEGPGLRLDEAYRVTASVRRIREARGERAVGRKIGFTNTTIWDEYGVRAPIWGYVYDTTLHRPEGLAGTFSLARTVEPRIEPEIVLGLARAPEPDMDEAALLGCLDFVAHGFEVVQSLFPGWRFTAADTVAAFGLHGALLMGPPAAVTPANAAAWGASLAGFRITLLRDGAEADRGRAENVLGGGPLAALRHLVRVLAEDPESPPLAAGEVVTTGTLTRALPVAPGETWSTRLDGLPLAGVTVAFA

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Crispr_ID: NC_010511_9

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_010511_9

1555920-1556022

Orphan

Consensus_repeat	Method
CGGATTTCGGCTTCGCTCAAGCGCCGCGCGGGCTT	CRISPRCasFinder

1 spacers

The CRISPR arrays of NC_010511_9

>merge|NC_010511|9|1555920-1556022|CRISPRCasFinder
CGGATTTCGGCTTCGCTCAAGCGCCGCGCGGGCTTGGCATACGACGACCGACGGATTGCTTCGCCATGCGGATTTCGGCCTCGCTCAAGCGCCGCGCGGGCTT

>NC_010511|9|9|1555920-1556022|CRISPRCasFinder
CGGATTTCGGCTTCGCTCAAGCGCCGCGCGGGCTT	GGCATACGACGACCGACGGATTGCTTCGCCATG
CGGATTTCGGCCTCGCTCAAGCGCCGCGCGGGCTT

Protein	Signature genes	Signature genes Name	Protein_function
NC_010511.1\|WP_012331342.1\|1549108_1549747_-\|16S-rRNA-(guanine(527)-N(7))-methyltransferase-RsmG	unknown	unknown	gnl\|CDD\|234637
NC_010511.1\|WP_012331338.1\|1545683_1546220_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|227755
NC_010511.1\|WP_012331337.1\|1542903_1545519_+\|leucine--tRNA-ligase	unknown	unknown	gnl\|CDD\|234743
NC_010511.1\|WP_012331349.1\|1558000_1558918_+\|polyphosphate-kinase-2	unknown	unknown	gnl\|CDD\|213852
NC_010511.1\|WP_012331344.1\|1551804_1553118_-\|tRNA-uridine-5-carboxymethylaminomethyl(34)-synthesis-GTPase-MnmE	unknown	unknown	gnl\|CDD\|235392
NC_010511.1\|WP_012331354.1\|1563302_1564514_-\|ABC-transporter-substrate-binding-protein	unknown	unknown	gnl\|CDD\|380550
NC_010511.1\|WP_012331347.1\|1556089_1557250_-\|PLP-dependent-transferase	unknown	unknown	gnl\|CDD\|223699
NC_010511.1\|WP_012331343.1\|1549746_1551630_-\|tRNA-uridine-5-carboxymethylaminomethyl(34)-synthesis-enzyme-MnmG	unknown	unknown	gnl\|CDD\|235362
NC_010511.1\|WP_012331356.1\|1566055_1567171_-\|hypothetical-protein	unknown	unknown	unknown
NC_010511.1\|WP_012331351.1\|1561320_1561767_-\|(2Fe-2S)-binding-protein	unknown	unknown	gnl\|CDD\|224991
NC_010511.1\|WP_012331340.1\|1547338_1548232_-\|ParB/RepB/Spo0J-family-partition-protein	unknown	unknown	gnl\|CDD\|275105
NC_010511.1\|WP_012331348.1\|1557331_1557844_+\|tryptophan-rich-sensory-protein	unknown	unknown	gnl\|CDD\|320706
NC_010511.1\|WP_012331339.1\|1546216_1547245_+\|DNA-polymerase-III-subunit-delta	unknown	unknown	gnl\|CDD\|235834
NC_010511.1\|WP_043702119.1\|1564659_1565994_-\|hypothetical-protein	unknown	unknown	unknown
NC_010511.1\|WP_043700900.1\|1548266_1549112_-\|ParA-family-protein	unknown	unknown	gnl\|CDD\|379293
NC_010511.1\|WP_012331350.1\|1559035_1561309_-\|xanthine-dehydrogenase-family-protein-molybdopterin-binding-subunit	unknown	unknown	gnl\|CDD\|224446
NC_010511.1\|WP_012331353.1\|1562397_1563222_-\|aldo/keto-reductase	unknown	unknown	gnl\|CDD\|381357
NC_010511.1\|WP_012331346.1\|1555311_1555776_-\|hypothetical-protein	unknown	unknown	unknown
NC_010511.1\|WP_012331352.1\|1562064_1562331_-\|hypothetical-protein	unknown	unknown	unknown
NC_010511.1\|WP_012331345.1\|1553318_1555193_+\|glucans-biosynthesis-glucosyltransferase-MdoH	unknown	unknown	gnl\|CDD\|235476

Protein	Function_ID	Function_description	E-value
NC_010511.1\|WP_012331342.1\|1549108_1549747_-\|16S-rRNA-(guanine(527)-N(7))-methyltransferase-RsmG	gnl\|CDD\|234637	PRK00107, gidB, 16S rRNA (guanine(527)-N(7))-methyltransferase RsmG.	6.48926e-56
NC_010511.1\|WP_012331338.1\|1545683_1546220_+\|hypothetical-protein	gnl\|CDD\|227755	COG5468, COG5468, Predicted secreted (periplasmic) protein [Function unknown].	6.67772e-17
NC_010511.1\|WP_012331337.1\|1542903_1545519_+\|leucine--tRNA-ligase	gnl\|CDD\|234743	PRK00390, leuS, leucyl-tRNA synthetase; Validated.	0
NC_010511.1\|WP_012331349.1\|1558000_1558918_+\|polyphosphate-kinase-2	gnl\|CDD\|213852	TIGR03707, PPK2_P_aer, polyphosphate kinase 2, PA0141 family. Members of this protein family are designated polyphosphate kinase 2 (PPK2) after the characterized protein in Pseudomonas aeruginosa. This family comprises one of three well-separated clades in the larger family described by pfam03976. PA0141 from this family has been shown capable of operating in reverse, with GDP preferred (over ADP) as a substrate, producing GTP (or ATP) by transfer of a phosphate residue from polyphosphate. Most species with a member of this family also encode a polyphosphate kinase 1 (PPK1). [Central intermediary metabolism, Phosphorus compounds].	7.58352e-147
NC_010511.1\|WP_012331344.1\|1551804_1553118_-\|tRNA-uridine-5-carboxymethylaminomethyl(34)-synthesis-GTPase-MnmE	gnl\|CDD\|235392	PRK05291, trmE, tRNA uridine-5-carboxymethylaminomethyl(34) synthesis GTPase MnmE.	0
NC_010511.1\|WP_012331354.1\|1563302_1564514_-\|ABC-transporter-substrate-binding-protein	gnl\|CDD\|380550	cd06327, PBP1_SBP-like, periplasmic substrate-binding domain of active transport proteins (substrate binding proteins or SBPs). Periplasmic substrate-binding domain of active transport proteins found in gram-negative, gram-positive bacteria, and archaea. Members of this group are initial receptors in the process of active transport across cellular membrane, but their substrate specificities are not known in detail. However, they closely resemble the group of AmiC and active transport systems for short-chain amides and urea (FmdDEF), and thus are likely to exhibit a ligand-binding mode similar to that of the amide sensor protein AmiC from Pseudomonas aeruginosa. Moreover, this binding domain has high sequence identity to the family of hydrophobic amino acid transporters (HAAT), and thus it may also be involved in transport of amino acids.	8.11029e-172
NC_010511.1\|WP_012331347.1\|1556089_1557250_-\|PLP-dependent-transferase	gnl\|CDD\|223699	COG0626, MetC, Cystathionine beta-lyases/cystathionine gamma-synthases [Amino acid transport and metabolism].	2.83276e-131
NC_010511.1\|WP_012331343.1\|1549746_1551630_-\|tRNA-uridine-5-carboxymethylaminomethyl(34)-synthesis-enzyme-MnmG	gnl\|CDD\|235362	PRK05192, PRK05192, tRNA uridine-5-carboxymethylaminomethyl(34) synthesis enzyme MnmG.	0
NC_010511.1\|WP_012331351.1\|1561320_1561767_-\|(2Fe-2S)-binding-protein	gnl\|CDD\|224991	COG2080, CoxS, Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS/CutS homologs [Energy production and conversion].	1.05831e-70
NC_010511.1\|WP_012331340.1\|1547338_1548232_-\|ParB/RepB/Spo0J-family-partition-protein	gnl\|CDD\|275105	TIGR04285, parB-like_partition_protein, nucleoid occlusion protein. This model describes nucleoid occlusion protein, a close homolog to ParB chromosome partitioning proteins including Spo0J in Bacillus subtilis. Its gene often is located near the gene for the Spo0J ortholog. This protein bind a specific DNA sequence and blocks cytokinesis from happening until chromosome segregation is complete.	7.45207e-77
NC_010511.1\|WP_012331348.1\|1557331_1557844_+\|tryptophan-rich-sensory-protein	gnl\|CDD\|320706	cd15904, TSPO_MBR, Translocator protein (TSPO)/peripheral-type benzodiazepine receptor (MBR) family. This family contains tryptophan-rich translocator protein (TSPO), an integral membrane protein that is highly conserved from bacteria to mammals. In eukaryotes, it is mainly found in the outer mitochondrial membranes of steroid-synthesizing cells of the nervous system where it transports cholesterol into mitochondria. It is known to be highly expressed in metastatic cancer, steriodogenic tissues, as well as inflammatory and neurological diseases such as Alzheimer's and Parkinson's. TSPO is also known as the peripheral benzodiazepine receptor (MBR) and its ligands include benzodiazepine drugs, implicated in regulating apoptosis. In human, a single polymorphism A147T is associated with psychiatric disorders; the mutation causes structural changes in a region implicated in cholesterol binding. TSPO is homologous to bacterial tryptophan-rich sensory proteins, and their tryptophan residues are believed to be functionally important. In bacteria, TSPO acts as a negative regulator of expression of specific photosynthesis genes in response to oxygen/light; it catalyzes a photooxidative degradation of Proto porphyrine (PpIX). R. sphaeroides TSPO (RsTSPO) is involved in porphyrin transport, similar to human, while Arabidopsis translocator protein (AtTSPO) is regulated at multiple levels in response to salt stress and perturbations in tetrapyrrole metabolism.	5.21541e-43
NC_010511.1\|WP_012331339.1\|1546216_1547245_+\|DNA-polymerase-III-subunit-delta	gnl\|CDD\|235834	PRK06585, holA, DNA polymerase III subunit delta; Reviewed.	2.41779e-132
NC_010511.1\|WP_043700900.1\|1548266_1549112_-\|ParA-family-protein	gnl\|CDD\|379293	pfam13614, AAA_31, AAA domain. This family includes a wide variety of AAA domains including some that have lost essential nucleotide binding residues in the P-loop.	3.83084e-84
NC_010511.1\|WP_012331350.1\|1559035_1561309_-\|xanthine-dehydrogenase-family-protein-molybdopterin-binding-subunit	gnl\|CDD\|224446	COG1529, CoxL, Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL/CutL homologs [Energy production and conversion].	1.31702e-87
NC_010511.1\|WP_012331353.1\|1562397_1563222_-\|aldo/keto-reductase	gnl\|CDD\|381357	cd19131, AKR_AKR5C2, Escherichia coli 2,5-diketo-D-gluconic acid reductase A (DkgA/YqhE) and similar proteins. Escherichia coli DkgA/YqhE is a founding member of aldo-keto reductase family 5 member C2 (AKR5C2). DkgA/YqhE (EC 1.1.1.274), also called 2,5-DKG reductase A, or 2,5-DKGR A, or 25DKGR-A, or AKR5C, catalyzes the reduction of 2,5-diketo-D-gluconic acid (25DKG) to 2-keto-L-gulonic acid (2KLG). It is also capable of stereoselective -keto ester reductions on ethyl acetoacetate and other 2-substituted derivatives.	8.84711e-153
NC_010511.1\|WP_012331345.1\|1553318_1555193_+\|glucans-biosynthesis-glucosyltransferase-MdoH	gnl\|CDD\|235476	PRK05454, PRK05454, glucans biosynthesis glucosyltransferase MdoH.	0

>NC_010511.1|WP_012331346.1|1555311_1555776_-|hypothetical-protein
MPAALPAALLGAHVLLAAADGPPRFNIEATCKSPGRASVSNDAGADGCLRSERAAGDDLRKRWGDFSGTAKRQCSQQSRAGGFPSYVEMLTCLELASGNVPVHGPENGATAGQGGAGPATTGSTRRGEEGTALTTAPSPQQRTDPLRVLGKPAR
>NC_010511.1|WP_012331345.1|1553318_1555193_+|glucans-biosynthesis-glucosyltransferase-MdoH
MPPASPPDAALIVRRLALALPTLATAAALAGLAAAASPADGLLDGAVLVLFCLVMTWQAYVAWQYVYGAAAAWLKRRVVSAVEAAAPTVPLAPSGRSRTVLAVAIHAEDPVAVFAAIRVMARSIARAGGGGDIDIFVLSDTRDAAIAAAEERELARARAWCEAAGPGLPRLRYRRRAENTGRKAGNIAEFCRRHGDAYEFMVVLDADSLMSGATIRRLIRLMEAHPRVGLIQTVSYAAGRDTLFARIQQFAVRLYAPLSIRALDTWQGPDGSYWGHNAILRLRAFAAHADLPVLPGRPPLGGEILCHDTVEGALLRRAGWELRLLPEEGGTWEEMPTNLVDLLGRERRWCQGNLQHLGLVGTPGLTAGSRWHLLVGILSYLASPLWLAFLTLGTARAVLRGDLGLLAYGLTGEGEAAGALAALTLAVLAAPKLLSLGHVLLSRERRSAFGGTRRLLLSAALEQVVWVLLWPVLMLFNAGAVASTLAGKVVRWDAQVRDDRQVPWSEAARLQADALIAGGVLAILLAVAGDPWLAAWMGPVAASLLLSPALSVLTSRADLGQGARRRGLFLTVDDTAQAPELRDLAAARAGRPPEPERPRAQPVAGEGPVWLATVTDDAAASPPR
>NC_010511.1|WP_012331344.1|1551804_1553118_-|tRNA-uridine-5-carboxymethylaminomethyl(34)-synthesis-GTPase-MnmE
MTDTIFAPASGFGRAAVAVIRISGPGAASCLTALTGHPPPLPRRLSLRQLRDPGTGEVLDRALVVWLPGPATFTGEDSAELHLHGGAAVRAAVLRVLGRLPGLAPAEPGAFTRRAFLNGRMDLTAVEGLADLIDAETEAQRRQAMRQLDGALGRLVEAWRDTLLGVLAGAEAALDFSDEGDVDESALSASGLAAAARVRDAILAALAEGRRGERLREGFVVVLAGPPNAGKSTLLNALARREAAIVSPIPGTTRDAIEVRCDLDGLPVLLVDTAGLRDEGADPIEAEGMARSRRRIEEADLVLWLVPPEGGAAAPKGALVVHTKRDLGRDPGGGVDGALAISALTGEGLAMLLDRVAAAAGAALGRGDAVVTRERQRRALEECAAHLGRAIAGAETMPAELVAEDLRLAVRALGAVAGRVGVEEMLDRLFSSFCIGK
>NC_010511.1|WP_012331343.1|1549746_1551630_-|tRNA-uridine-5-carboxymethylaminomethyl(34)-synthesis-enzyme-MnmG
MQRIDRTRFDVIVVGGGHAGVEAAAAAARLGAATALVTHRRATLGAMSCNPAIGGLGKGHLVREVDALDGLMGRVADRAGIQFRLLNRRKGPAVRGPRSQADRKLYARAMQEALAATPNLSLIEGEAHDLAVVEGRVTGIVLADGRALPCAAVVLTTGTFLRGLIHIGERTMPAGRVGEAPALGLAATLDRHGFGLGRLKTGTPARLDGRTIDWAGIEKQAADDEPVPFSSLTDRITTPQIECGVTRTTQAVHDLIRANLHRSPMYSGGITSRGPRYCPSIEDKVVRFGDRDGHQIFLEPEGLDDPTIYPNGISTALPEEVQRAVLRLIPGCERAAMLRPGYAIEYDYVDPRELDPTLQTRRVAGLFLAGQINGTTGYEEAAGQGILAGINAARLAAGSALAVLDRAESYIGVMIDDLVTHGVSEPYRMFTSRSEYRLSLRVDNADERLTGRGIALGCVGAARARHFAESQQALAAARARLDALAITPSEAARHGLALNRDGIRRSAFQLLSYPEIDWPRLAAIWPELAAVPPRVAERLRTDAAYAVYLDRQRSDIAAFRRDEAVRLPASLDYGRIAGLSNELRLKLDCVRPHTLGQAARIEGVTPAALTLLAAHARRADAAAPAEA
>NC_010511.1|WP_012331342.1|1549108_1549747_-|16S-rRNA-(guanine(527)-N(7))-methyltransferase-RsmG
MVPSDRDRVLAEAGVSRETAAALDLYVAQLTRWQAIKNLVGPATLPDVWTRHIADSLQLLDAAPQARTWLDLGSGAGIPGLILAIAGVRNRPDLRVDLVESNARKGAFLQETARLTGAPARIHVARIERVVAGFRGVDVVCARALAPLPQLIAWTAPLLKSGTIGLFPKGREAQSELTAAREKWTFVADVIPSRTDSSAGIVRISSLSDPLP
>NC_010511.1|WP_043700900.1|1548266_1549112_-|ParA-family-protein
MTVEPSEAPARSARPLRIIALANQKGGVGKTTTAINLGTALAAIGEQVLIIDLDPQGNASTGLGIDRRQRRLSTYDVLAGEAALKEAVQATAVPRVAIAPSTMDLLGLEMEMASAQDRAHRLRRVLEPLTRGEMAEEERFTYVLIDCPPSLNLLTINALAAADAVLVPLQCEFFALEGLSQLLRTVEQVRGTLNPRLAIQGIVLTMFDPRNNLSTQVVADVRAFMGDKVYETMIPRNVRVSEAPSHGKPVLLYDLKCAGSQAYLRLASEIIQREGRLPAAA
>NC_010511.1|WP_012331340.1|1547338_1548232_-|ParB/RepB/Spo0J-family-partition-protein
MAEEVARPRLGRGLAALIGDVGEDAPPAPIDRRGQRRVPIEFLRPNPRNPRRHFAEAELEELSASIRTRGVIQPIVVRGVAAVPDTFEIVAGERRWRAAQRAGLHEVPVVVVEIDDRTSLEYAILENVQRADLNPIEEAAGYERLMSEFGYSQTELAEIMGKSRSHLANTLRLLNLPPSVQEQVVAGALTAGHARALLAVRDPEAVARRVVAEGLTVREVEALAAAEQPAESGPRPGRPRRAPPEKDADTRALERRLEDALGVTVSIEHRGGGGELRLRYASLDQLDAICRRLEMQG
>NC_010511.1|WP_012331339.1|1546216_1547245_+|DNA-polymerase-III-subunit-delta
MTAIRPGDVEGLLRRGPDPRVAVILVYGPDTGLVAERARSLAEGAVADPSDPFALVKIDGDVLAGDPGRLLDEAGTVGLFGGQRAIWVRPGSRPIAPAVEALLKAELPAARVVVEAGDLAKSAPLRVLCERSPRALALPCYPDDARTLADLIDARLQAEGLRIARDARETLAASLGGDRRASLGEIEKLALYARGQREISLEDVEAVASDVSGSVLNALIDAAFAGQAGEAERSYRRFRVEGMDASVMLGAALRHALALLAARLDGQGQSPGQIVASWRGLHFRRQRIVEVQLARWSPEALRRAVARLQEAVLACRRAEAEFAHALASDVLVRIALEAGRRA
>NC_010511.1|WP_012331338.1|1545683_1546220_+|hypothetical-protein
MARSTVGTARRFALAGMVMLGLSGCFRPLYGPTASGAPLSAVLASIQVDPATTAQGQERLGHYLRSELVFDLDGAGQAPEKRYRLTLAVSETVQTPIVSSVTARAESATLYGSAAYKVVSLDGSRTLTEGTATGLASYDRSVQRFASLRAARDAEIRLAKLLADQIKTRVAAILATQP
>NC_010511.1|WP_012331337.1|1542903_1545519_+|leucine--tRNA-ligase
MAERYNPKESEPHWQAVWAERDLFRTRNEDPRPTYYVLEMFPYPSGRIHMGHVRNYAMGDVVARYKRAKGFNVLHPMGWDAFGLPAENAAMERKINPREWTYANIATMKGQLKAMGLSLDWSREVATCDPSYYKHQQRMFLDFLKAGLVTRRTAKVNWDPVDHTVLANEQVIDGRGWRSGALVEQRELTQWFFRITDYAQDLSDRLDTLERWPEKVRLMQKNWIGRSEGLELRFALAAPDGAAPDGAPDGVPSEVKVYTTRPDTLFGAKFLAVAADHPLAAAVAATSPALRDFIAECRRIGTAQEAIDTAEKLGFDTGLKVRHPLDPTWLLPVYVANFVLMEYGTGAVFGCPAHDQRDLDFANKYGLGNVPVVCPPGTDPAGFVITDVAYEGDGRMINSRFLDGMTTEAAFAAVAARLEAERLGEAPVAQRRVQFRLRDWGVSRQRYWGCPIPVIHCESCGVVPVPVEDLPVTLPEEVSFDQPGNPLERDAAWRNVPCPVCGAPARRETDTMDTFVDSSWYFARFTAPWLTDAPTDPATADRWLPVDQYIGGIEHAILHLLYSRFFARAMRKVGWGGADEPFAGLFTQGMVVHETYKDASGAWVQPVDVRIAVEDGERRAFHVKTGAPIIIGSIEKMSKSKRNVVDPDDIIASYGADTARWFMLSDSPPERDVIWTEDGVQGASRFVQRVWRLVNEIAERPEQAGDAAADLALRKAAHRALAALGEDIERLRFNRCVAHLYELANTLQDALAGPAPLGRPALIETGRILVQLLAPMMPHLAESSWAVLGQPGLVAEAPWPEADPALLVEASITLPVQVNGRKRADVTVPREADAAAVEAAVLALEAVQRALDAKAPRKVIVVPQRIVNVVA
>NC_010511.1|WP_012331347.1|1556089_1557250_-|PLP-dependent-transferase
MSRETPSPWSKRSLAVQAMGHVDPVTKAVVPPIHLTSTYLRDPDNQYSSGYCYGRPDNATVREAEAVLAMLEEAPAGALLFGSGMAAATAVFGALDPGDHVVAPSVMYWALRRWLLQEATRWGLKVDLVATDDLDALRAAVVPGRTKLVWLETPSNPLWTITDIAAAAEIAHAAGARLAVDSTAASPVVTRPLALGADVVMHSATKVLNGHSDVIAGVLAGAREDAFWGRIKGIRASQGAILGPFEAFLLLRGLRTLHLRIAAQMRGAAALADRFTAHPRVHAVLYPGLADHPGHAVAARQMEGGFGTMLSIRVAGGEAAAIATAARVSLWKRATSLGGVESLIEHRASVEGPGTPCPADLLRLSTGIEDPEDLFADLDAALRGAA
>NC_010511.1|WP_012331348.1|1557331_1557844_+|tryptophan-rich-sensory-protein
MTLAATRLAVPSPALRLALAVLPVLATALTGPLFTTPNIPTWYAGLAKPGFTPPNWMFPVAWSMLYAMIALACWRVLGTAPASADLRRGRSVALAAYAVQLALNAIWTPVFFAAHSLLGGLVVIVALLVMILWTIRLFWPLDRAAALLLVPYAGWVAYATAVNAAVWRMN
>NC_010511.1|WP_012331349.1|1558000_1558918_+|polyphosphate-kinase-2
MEDDLKAARVEAVREEVADSLDEEMELELDEAFLERVADGVEPPNRAPTLPRAVYFRELLRLQQELVRLQDYVQVHRKRVVVLFEGRDAAGKGGVIKRITQRLNPRVCRIAALPAPSERERTQWYFQRYVAHLPAGGEIVLFDRSWYNRAGVERVMGFCTDDEYEEFFRSVPEFERMLVRSGIILVKYWFSITDEEQEFRFRMRINDPLKQWKLSPMDVQSRARWELYTRAKETMLERTHIPEAPWWVVEAVDKKRARLNCIAHLLEQVPYGAVERPPVDLPERVRHPDYERHPVPAEMHVPARY
>NC_010511.1|WP_012331350.1|1559035_1561309_-|xanthine-dehydrogenase-family-protein-molybdopterin-binding-subunit
MTRPARSPLPSLPAVAPEGVANLSRRRFLGRAAGALVLGIALPARGRAEAQGPAEGAGAIAPQPGTRVPAFLEIRPDGRVRLLSPFVEGGQGIATGMAQIVGEELDVDPARFLVECAPPGPDYAVVNGLRMTGGSFSTRSSYALMRQLGATARDMLIRAAAARLKVEAGSLATRDGAVVHPASGRTLPYGDLAGEALALKPRDGVPLRDPASFRYIRRPVPRLDVRDKATGRAVYAIDQTVEGMLHAAVQHAPHLGTEPLSLANEDEVRRMPGVHSVHRLPGAVAVAADSWWRARKAVEALRVRWSAPEPEGIATVSATFSSEAMRAALADAPGEAQVGEAQVAEAEGDAGGAFASAARVIEAAYEAPYLAHAQLEPPSAIARFNPDGTLDVWTPNQMPELFQALSAQAAGLAPDRVRIHSPMLGGFFGRHFAYGPANPYPQAILLARATGRPVRVLWSREEEFGSDALRPLSASRFRAALDAAGRPIALEVRTVGEGPIGRWFGAMVQGPVDPSAVEGLVRKPYAIPNRRMTFVKRAHPVTIAFWRSVGHSMNDYFYESFLDEIAQAGGQDPFALRMALVAGSPRHRRLLEEVADLSGGWKRGPYEAEGGRRARGLAMASPFGSETATVAEVSVEGGEARVHTLWIAFDPGSVVNPAIVKAQVESAAALGLSATLVEQMLYRDGQRQARNFDAYPILRREHMPAVHVRIVESGAPMGGVGEPGLPGVPPAVANAVAALTGQRVRALPLSNVRLSGA
>NC_010511.1|WP_012331351.1|1561320_1561767_-|(2Fe-2S)-binding-protein
MFHLTINGRDHQVEVEPDTPLLFVLRDTLGMTGTKYGCGIAQCGACTVLIDGQATRSCQVPIESVGAARVRTIEAIEQDPVGRRVVEAWVAEQVPQCGYCQSGQVMAATALLTQNPKPTDEDIAAAMTNLCRCGTYNRIAAAVRQAAA
>NC_010511.1|WP_012331352.1|1562064_1562331_-|hypothetical-protein
MRTYTLAFADVLYACLPDGADIDRVIEEEACVGCAEIDPGEVRVVRGLTLTAFPAAADEVVWCAGSDGDLTDVHGRCFPYAVRRWVDR
>NC_010511.1|WP_012331353.1|1562397_1563222_-|aldo/keto-reductase
MTQPTLTLNDGKRVPQLGFGVWKLADEKAPEIVGLALEAGYRAIDTAAVYGNEAGVGRAIAASGLAREEIFVTTKLWNDSHGSDEVLRACDASLERLGLDHVDLYLVHWPLPQRDLYVQTWRAMMRLREDGRARSIGVSNFTVAQLKRVIDETGSTPSVNQIELHPRFQQRALRDFHARAGIVTQAWSPLGRGAALADPVIRGIAEKHGRTPAQVILRWHIESGSAVIPKSETPARIRENADIFGFALDPEDQAAIAALDAADGRIGPDPETFG
>NC_010511.1|WP_012331354.1|1563302_1564514_-|ABC-transporter-substrate-binding-protein
MSPRSLRQVLAAGFAALLSVSAAAQEAVPPVKVGVLSDMSGPFADQAGTGSVVAAQLAAEDFAKETPDIRVEVVSADHQNKPDIGLAIARKWLDQESVSTIVDLPNSAVALAVANLMRERHRVALASSAMTSDLTGKACAPTTVQWVSDTWAQGSATARAIAERGFKSWYFLTVDYALGQALERDATAALKGMGGSVKGSTKHPLNAGDFASPLLAAQGSGAQVLALANTGADMINVVKQAAEFGLMPDMRVAALFIQISDVHALGLKAAQGLQFASAFYWDRTDGTRAFAKRFAERMNGRMPTENHAGVYSATLAYLRGVRAAATVEGEKVLAALRETPIDDPLFGPVTIRQDGRAVHDLFLFEVKTPAESKGPYDYYKLLATVPGDKAFRPMSEGGCPLAK
>NC_010511.1|WP_043702119.1|1564659_1565994_-|hypothetical-protein
MKGEVSHHVDALQAIMVLSNDDAIMRHDTAGYYVVARRNPEIEATWIGCYKPLPQGVVGRSGGYFGCGLWLFGTHLDGGEAVALLEAIIGRIESLLSSGLIRDTGALRLEDLEGDVSKLHDAERAQRSNRPRQGLSFTLLGTPAVIDLSREADSAALPDALTRAQRDGLFEPYAKVLIARDAAAMRGVRAPGPRLDARARGAAGEERERGSIWSGWRSPSAPSPDLARLPPPQALPSPRAEAGRAPSGLAEVQQAWQRQFGAVERRIDALDAALRLATRRNQAGLLALAGASAIGLGAVSWWGIASSPPPALTSSPGRPASGSPPLRSSADPAARQFGPPDAPRDRQDLPDSRTEAAPAQQDFGAVVGALEKSLLTLQGLIASNDLPKNLVAKHNLRGNFNEIIAALQPVGDFRVRELVDRLKPRAADEPAKVPNAEPTRRGSP
>NC_010511.1|WP_012331356.1|1566055_1567171_-|hypothetical-protein
MNDANGHNFSSDQAFDDDDIEHADFESPLLAREIMSHLRNNDIHPVMIFGTNSSGKTMMLLSLIDYIKSSDDAVVDVQLRAPIWPRRHGYFAPIEEAARAFFENQVAAFGRGYAAPRTQRETPYFIPVNIVHERRTVKFAFLEGMGEWFEQQKPAAGQAADASRMPPFLPFRNLLKEILQHYELGMSLIFVAPTVAGPDGESAASSHECLSNAMHQVDRLRGNKNRDNLLLLISKWDACCPPGVNGSGFSDATASTVLDRIARWRVAWPKFAAMTGFPAHSKALMPYSAAWVQPDRRITHSPIYAPVFRRFNRTLWNWLYGNATAALPHGGGAREILYADVVPSPVEEAGPYETLTRVMILSVFSKLFRER

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Crispr_ID: NC_010511_10

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_010511_10

1942063-1942206

TypeI

Consensus_repeat	Method
CATGGCCGCCACCAATGAGGCGGAGAGGAATGAGCGGCAGGACGGCGA	CRISPRCasFinder

1 spacers

cas8c,cas5,cas3,cas3HD,cas1,cas2

The CRISPR arrays of NC_010511_10

>merge|NC_010511|10|1942063-1942206|CRISPRCasFinder
CATGGCCGCCACCAATGAGGCGGAGAGGAATGAGCGGCAGGACGGCGAAGACAAGGCCGGGAAGCGCGGCGACAAGCGCACCATGGGCCGCAAGCACATGGCCGCCACCAACGAGGCGGAGAGGAATGAGCGGCAGGACGGCGA

>NC_010511|10|10|1942063-1942206|CRISPRCasFinder
CATGGCCGCCACCAATGAGGCGGAGAGGAATGAGCGGCAGGACGGCGA	AGACAAGGCCGGGAAGCGCGGCGACAAGCGCACCATGGGCCGCAAGCA
CATGGCCGCCACCAACGAGGCGGAGAGGAATGAGCGGCAGGACGGCGA

Protein	Signature genes	Signature genes Name	Protein_function
NC_010511.1\|WP_012331621.1\|1929251_1930124_-\|serine-protease	unknown	unknown	gnl\|CDD\|223343
NC_010511.1\|WP_012331632.1\|1946506_1947295_+\|SDR-family-oxidoreductase	unknown	unknown	gnl\|CDD\|235546
NC_010511.1\|WP_012331622.1\|1930228_1931644_-\|DegQ-family-serine-endoprotease	unknown	unknown	gnl\|CDD\|273938
NC_010511.1\|WP_043700754.1\|1936205_1937411_+\|IS30-family-transposase	unknown	unknown	gnl\|CDD\|225382
NC_010511.1\|WP_012331629.1\|1943315_1943606_+\|CRISPR-associated-endonuclease-Cas2	cas2	cd09725_cas2_CAS-I:CAS-II:CAS-III:CAS-V	gnl\|CDD\|187856
NC_010511.1\|WP_012331630.1\|1944271_1945162_-\|LysR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|182990
NC_010511.1\|WP_012331631.1\|1945440_1946448_+\|TRAP-transporter-substrate-binding-protein	unknown	unknown	gnl\|CDD\|224553
NC_010511.1\|WP_012331623.1\|1931717_1932983_-\|glycosyltransferase	unknown	unknown	gnl\|CDD\|340850
NC_010511.1\|WP_018262003.1\|1947291_1948572_+\|ribulose-bisphosphate-carboxylase	unknown	unknown	gnl\|CDD\|173972
NC_010511.1\|WP_012331635.1\|1950037_1950865_+\|3-oxoacyl-ACP-reductase-FabG	unknown	unknown	gnl\|CDD\|235500
NC_010511.1\|WP_050777472.1\|1937434_1938583_+\|hypothetical-protein	cas3	COG1203_cas3_CAS-I	gnl\|CDD\|224124
NC_010511.1\|WP_012331634.1\|1948568_1949927_+\|four-carbon-acid-sugar-kinase-family-protein	unknown	unknown	gnl\|CDD\|225930
NC_010511.1\|WP_012331636.1\|1950861_1951881_+\|TRAP-transporter-substrate-binding-protein	unknown	unknown	gnl\|CDD\|270321
NC_010511.1\|WP_012331627.1\|1939767_1941570_+\|type-I-C-CRISPR-associated-protein-Cas8c/Csd1	cas8c	cd09757_cas8c_CAS-I-C	gnl\|CDD\|378245
NC_010511.1\|WP_018262010.1\|1934363_1934567_-\|hypothetical-protein	unknown	unknown	unknown
NC_010511.1\|WP_043700987.1\|1952047_1952902_+\|alpha/beta-fold-hydrolase	unknown	unknown	gnl\|CDD\|235135
NC_010511.1\|WP_083784650.1\|1942723_1943284_+\|CRISPR-associated-endonuclease-Cas1	cas1	cd09721_cas1_CAS-I-C	gnl\|CDD\|188360
NC_010511.1\|WP_043700984.1\|1939090_1939771_+\|type-I-C-CRISPR-associated-protein-Cas5	cas5	cd09752_cas5_CAS-I-C	gnl\|CDD\|187534
NC_010511.1\|WP_050777471.1\|1934812_1936270_+\|CRISPR-associated-endonuclease-Cas3''	cas3HD	cd09641_cas3HD_CAS-I	gnl\|CDD\|350688
NC_010511.1\|WP_012331624.1\|1933081_1934350_+\|glycosyltransferase-family-4-protein	unknown	unknown	gnl\|CDD\|340831

Protein	Function_ID	Function_description	E-value
NC_010511.1\|WP_012331621.1\|1929251_1930124_-\|serine-protease	gnl\|CDD\|223343	COG0265, DegQ, Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain [Posttranslational modification, protein turnover, chaperones].	8.21041e-31
NC_010511.1\|WP_012331632.1\|1946506_1947295_+\|SDR-family-oxidoreductase	gnl\|CDD\|235546	PRK05653, fabG, 3-oxoacyl-ACP reductase FabG.	9.37799e-77
NC_010511.1\|WP_012331622.1\|1930228_1931644_-\|DegQ-family-serine-endoprotease	gnl\|CDD\|273938	TIGR02037, Probable_periplasmic_serine_protease_do/HhoA-like, periplasmic serine protease, Do/DeqQ family. This family consists of a set proteins various designated DegP, heat shock protein HtrA, and protease DO. The ortholog in Pseudomonas aeruginosa is designated MucD and is found in an operon that controls mucoid phenotype. This family also includes the DegQ (HhoA) paralog in E. coli which can rescue a DegP mutant, but not the smaller DegS paralog, which cannot. Members of this family are located in the periplasm and have separable functions as both protease and chaperone. Members have a trypsin domain and two copies of a PDZ domain. This protein protects bacteria from thermal and other stresses and may be important for the survival of bacterial pathogens.// The chaperone function is dominant at low temperatures, whereas the proteolytic activity is turned on at elevated temperatures. [Protein fate, Protein folding and stabilization, Protein fate, Degradation of proteins, peptides, and glycopeptides].	7.02285e-173
NC_010511.1\|WP_043700754.1\|1936205_1937411_+\|IS30-family-transposase	gnl\|CDD\|225382	COG2826, Tra8, Transposase and inactivated derivatives, IS30 family [DNA replication, recombination, and repair].	8.01138e-92
NC_010511.1\|WP_012331629.1\|1943315_1943606_+\|CRISPR-associated-endonuclease-Cas2	gnl\|CDD\|187856	cd09725, Cas2_I_II_III, CRISPR/Cas system-associated protein Cas2. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas2 is present in majority of CRISPR/Cas systems along with Cas1; RNAse specific to U-rich regions; Possesses an RRM/ferredoxin fold.	4.45977e-24
NC_010511.1\|WP_012331630.1\|1944271_1945162_-\|LysR-family-transcriptional-regulator	gnl\|CDD\|182990	PRK11139, PRK11139, DNA-binding transcriptional activator GcvA; Provisional.	1.54273e-66
NC_010511.1\|WP_012331631.1\|1945440_1946448_+\|TRAP-transporter-substrate-binding-protein	gnl\|CDD\|224553	COG1638, DctP, TRAP-type C4-dicarboxylate transport system, periplasmic component [Carbohydrate transport and metabolism].	7.07982e-99
NC_010511.1\|WP_012331623.1\|1931717_1932983_-\|glycosyltransferase	gnl\|CDD\|340850	cd03823, GT4_ExpE7-like, glycosyltransferase ExpE7 and similar proteins. This family is most closely related to the GT4 family of glycosyltransferases. ExpE7 in Sinorhizobium meliloti has been shown to be involved in the biosynthesis of galactoglucans (exopolysaccharide II).	3.32836e-35
NC_010511.1\|WP_018262003.1\|1947291_1948572_+\|ribulose-bisphosphate-carboxylase	gnl\|CDD\|173972	cd08207, RLP_NonPhot, Ribulose bisphosphate carboxylase like proteins from nonphototrophic bacteria. Ribulose bisphosphate carboxylase (Rubisco) plays an important role in the Calvin reductive pentose phosphate pathway. It catalyzes the primary CO2 fixation step. Rubisco is activated by carbamylation of an active site lysine, stabilized by a divalent cation, which then catalyzes the proton abstraction from the substrate ribulose 1,5 bisphosphate (RuBP) and leads to the formation of two molecules of 3-phosphoglycerate. Members of the Rubisco family can be divided into 4 subgroups, Form I-IV, which differ in their taxonomic distribution and subunit composition. Form I-III have Rubisco activity, while Form IV, also called Rubisco-like proteins (RLP), are missing critical active site residues and therefore do not catalyze CO2 fixation. They are believed to utilize a related enzymatic mechanism, but have divergent functions. The specific function of this subgroup is unknown.	0
NC_010511.1\|WP_012331635.1\|1950037_1950865_+\|3-oxoacyl-ACP-reductase-FabG	gnl\|CDD\|235500	PRK05557, fabG, 3-ketoacyl-(acyl-carrier-protein) reductase; Validated.	4.39171e-89
NC_010511.1\|WP_012331634.1\|1948568_1949927_+\|four-carbon-acid-sugar-kinase-family-protein	gnl\|CDD\|225930	COG3395, COG3395, Uncharacterized protein conserved in bacteria [Function unknown].	3.01833e-62
NC_010511.1\|WP_012331636.1\|1950861_1951881_+\|TRAP-transporter-substrate-binding-protein	gnl\|CDD\|270321	cd13603, PBP2_TRAP_Siap_TeaA_like, Substrate-binding domain of a sialic acid binding Tripartite ATP-independent Periplasmic transport system (SiaP) and related proteins; the type 2 periplasmic-binding protein fold. This subfamily includes the periplasmic-binding component of TRAP transport systems such as SiaP (a sialic acid binding virulence factor), TeaA (an ectoine binding protein), and an uncharacterized TM0322 from hyperthermophilic bacterium Thermotoga maritima. TRAP transporters are a large family of solute transporters ubiquitously found in bacteria and archaea. They are comprised of a periplasmic substrate-binding protein (SBP) and two unequally sized integral membrane components: a large transmembrane subunit involved in the translocation process and a smaller membrane of unknown function. The driving force of TRAP transporters is provided by electrochemical ion gradients (either protons or sodium ions) across the cytoplasmic membrane, rather than ATP hydrolysis. This substrate-binding domain belongs to the type 2 periplasmic binding fold protein superfamily (PBP2). The PBP2 proteins are typically comprised of two globular subdomains connected by a flexible hinge and bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap.	4.49179e-111
NC_010511.1\|WP_012331627.1\|1939767_1941570_+\|type-I-C-CRISPR-associated-protein-Cas8c/Csd1	gnl\|CDD\|378245	pfam09709, Cas_Csd1, CRISPR-associated protein (Cas_Csd1). CRISPR loci appear to be mobile elements with a wide host range. This entry represents proteins that tend to be found near CRISPR repeats. The species range, so far, is exclusively bacterial and mesophilic, although CRISPR loci are particularly common among the archaea and thermophilic bacteria. Clusters of short DNA repeats with nonhomologous spacers, which are found at regular intervals in the genomes of phylogenetically distinct prokaryotic species, comprise a family with recognisable features. This family is known as CRISPR (short for Clustered, Regularly Interspaced Short Palindromic Repeats). A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins.	0
NC_010511.1\|WP_050777472.1\|1937434_1938583_+\|hypothetical-protein	gnl\|CDD\|224124	COG1203, COG1203, CRISPR-associated helicase Cas3 [Defense mechanisms].	7.02044e-25
NC_010511.1\|WP_043700987.1\|1952047_1952902_+\|alpha/beta-fold-hydrolase	gnl\|CDD\|235135	PRK03592, PRK03592, haloalkane dehalogenase; Provisional.	5.98733e-37
NC_010511.1\|WP_083784650.1\|1942723_1943284_+\|CRISPR-associated-endonuclease-Cas1	gnl\|CDD\|188360	TIGR03640, cas1_DVULG, CRISPR-associated endonuclease Cas1, subtype I-C/DVULG. The CRISPR-associated protein Cas1 is virtually universal to CRISPR systems. CRISPR, an acronym for Clustered Regularly Interspaced Short Palindromic Repeats, is prokaryotic immunity system for foreign DNA, mostly from phage. CRISPR systems belong to different subtypes, distinguished by both nature of the repeats, the makeup of the cohort of associated Cas proteins, and by molecular phylogeny within the more universal Cas proteins such as this one. This model is of type EXCEPTION and provides more specific information than the EQUIVALOG model TIGR00287. It describes the Cas1 protein particular to the DVULG subtype of CRISPR/Cas system.	1.36797e-106
NC_010511.1\|WP_043700984.1\|1939090_1939771_+\|type-I-C-CRISPR-associated-protein-Cas5	gnl\|CDD\|187534	cd09752, Cas5_I-C, CRISPR/Cas system-associated RAMP superfamily protein Cas5. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas5 is a RAMP superfamily protein; Subunit of the Cascade complex; in subtype I-C this protein might be the endoribonuclease that generates crRNAs; also known as DevS family.	1.15785e-102
NC_010511.1\|WP_050777471.1\|1934812_1936270_+\|CRISPR-associated-endonuclease-Cas3''	gnl\|CDD\|350688	cd17930, DEXHc_cas3, DEXH/Q-box helicase domain of Cas3. CRISPR-associated (Cas) 3 is a nuclease-helicase responsible for degradation of dsDNA. The two enzymatic units of Cas3, a histidine-aspartate (HD) nuclease and a Superfamily 2 (SF2) helicase, may be expressed from separate genes as Cas3' (SF2 helicase) and Cas3'' (HD nuclease) or may be fused as a single HD-SF2 polypeptide. The nucleolytic activity of most Cas3 enzymes is transition metal ion-dependent. Cas3 is a member of the DEAD-like helicase superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.	1.79409e-41
NC_010511.1\|WP_012331624.1\|1933081_1934350_+\|glycosyltransferase-family-4-protein	gnl\|CDD\|340831	cd03801, GT4_PimA-like, phosphatidyl-myo-inositol mannosyltransferase. This family is most closely related to the GT4 family of glycosyltransferases and named after PimA in Propionibacterium freudenreichii, which is involved in the biosynthesis of phosphatidyl-myo-inositol mannosides (PIM) which are early precursors in the biosynthesis of lipomannans (LM) and lipoarabinomannans (LAM), and catalyzes the addition of a mannosyl residue from GDP-D-mannose (GDP-Man) to the position 2 of the carrier lipid phosphatidyl-myo-inositol (PI) to generate a phosphatidyl-myo-inositol bearing an alpha-1,2-linked mannose residue (PIM1). Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate residue. This group of glycosyltransferases is most closely related to the previously defined glycosyltransferase family 1 (GT1). The members of this family may transfer UDP, ADP, GDP, or CMP linked sugars. The diverse enzymatic activities among members of this family reflect a wide range of biological functions. The protein structure available for this family has the GTB topology, one of the two protein topologies observed for nucleotide-sugar-dependent glycosyltransferases. GTB proteins have distinct N- and C- terminal domains each containing a typical Rossmann fold. The two domains have high structural homology despite minimal sequence homology. The large cleft that separates the two domains includes the catalytic center and permits a high degree of flexibility. The members of this family are found mainly in certain bacteria and archaea.	1.44856e-36

>NC_010511.1|WP_012331627.1|1939767_1941570_+|type-I-C-CRISPR-associated-protein-Cas8c/Csd1
MTMLQALDRYYDRLERRGEVVMPGWSTEPLGLVLELAEDGTPLGLADRLTARGKPQLDRVPKWFSRSGTGSTPFFLWDNLAYALGLGTKDPAKTARDHAAFRDLHLRELAGERDPALAALRRFVEAWVPDPEAARALGLQSRHMALNLGFRLRGETVPLHHRPAAAAHVERLRAAHEGGPEGFCLVRGARLPLVRLHPKVKGIDGGAAAEIPLVSFNQDAFTSYGHDQGFNAPTSAAAAFRYGAALNALLQRGGPNRLRIADSTVAFWADARAYDASVAEPIALAAEDIFGDALRDGPGPAGTTDARETQALREALVTVAEARAAPDLRPDLMENVPFFVLGLAPNMARVAVRYWLAGTFGSFRRALDAHAAALAIEPKPRGWGAKPPSPARLLLKTTALAEEFDNIPHGLAAEVTRAILENRPYPRTWLAATIARLRAGDDPGRGWHAAAIKACLNRRSEREMLPVALDPAHTDPAYQLGRLFAVLEAAQRTALPGVNTTIGDRWYAAASSTPARVFGPLLRSLKTHVADARKRGLGGWIEPKVAEIMQRLPPDLPRVLSLEAQGRFAVGYYHERGTRPEKKTDSPTTTGTDPEETPHG
>NC_010511.1|WP_043700984.1|1939090_1939771_+|type-I-C-CRISPR-associated-protein-Cas5
MTYGVRLHVWGERALFTRPETKVERVSYDVPTPSAARGILEAIHWKPAIVWRIDRIHVLKPIRFASVRRNEVGAKASTALALRAMRSGTLAGLGLSAEIERQQRAATMLVDVGYVIEAHLEMTARAGDDAPVKHICMFNRRAAAGQCFHRPCLGTRECPAEFALIPDGAPLPASSLPAEERERELGWMLYDIDFRPDRNEARFFRARLSKGILDVRACLAANEVVS
>NC_010511.1|WP_050777472.1|1937434_1938583_+|hypothetical-protein
MLLPCLAALEELTGNYGATVVLCTATQPAVRVRDGALRERFRPVDHGLPIGADRELAPRPERLADEVRRVTVEVLPEPIGDEVVAARFEAQKQMLCIVNSRAHARALFARIRGLPGAFYLTTLMCPAHRRAVLAEIKARLEDGRPVRLVATSLVEAGIDFSFPEVWRAEAGLDQIAQAAGRCNRNGELHPALGRVVVFTPAAHRPPRSLAAFQQAARPVLRDHPDPLGPDAIAAYFRLLYAERGLAELDAAEIDGQAGILAAFGRHGLERGFPFESVARAFRLIDETMVPVVVPWDAEAVQALAEVAGMERPTGEALRRLHPYTVGIPRQAHAGWCATREIVPVGPACGEVLTRFATMDLYDATIGIDLWATAARDGEADAP
>NC_010511.1|WP_043700754.1|1936205_1937411_+|IS30-family-transposase
MAPSHLSPSSKSPSARYLSLAEREEIAILQAQGHGVRDVARRLGRAASTISRELRRNAATRSGGLDYRATTAQWHAERAARRPKPAKLAGNAALRTYVQERLAGTVATPGGSALPGPSVAWKGRRHGRRQSRRWGRSWSPQQIAERLRLDFPGDTTMRISHEAIYQALYIQGRGALKRELTACLRTGRALRVPRARSLGRGRSFVTPEVLISERPPEVEDRAVPGHWEGDLILGLKSSAIGTLVERTTRFTMLLHLPPMDGHGVTPRAKNGPALAGHGAQAVREAIAGTIARLPEQLRRSLTWDQGTEMAEHARLRIDAGLQVYFCDPRSPWQRGTNENTNGLLRQYFPKGTDLSAHSANDLAAVAAALNSRPRKTLNWKTPAEALDAVLAAVQDGVATTA
>NC_010511.1|WP_050777471.1|1934812_1936270_+|CRISPR-associated-endonuclease-Cas3''
MSSVLYAHSKPGRPEAEWEPLAVHARWTGRFAAHFGRAFGCAGLARAQGLLHDTGKASQEFQDYLCALRARGGDHSTWGAQRADELYGRVVGRMLAACIAGHHGGLPDGEALRRRLAQAQNDASRWRELIIPLAPEVIASKRCFAPPARERFEQCPDALARRRAFTKAFLIRMLFSCLVDADFRATERFMADGRPRARVRTRLRDLDRQLTAHLRCKQADAKPTAINALRAEILAHAVAKATCTPGLFTLTVPTGGGKTLTSLAFALAHAERYGKRRVIHVAPFTAIVEQTADAIRTAVGNPGAILEHHANLDEEALARRLAEDGGDERDGLGPLRRAAATWDAPIVVTTAVQFFESLFANRPSRCRKLHNLANSVIILDEAQTVDSSGRRNGLAEGGCDGRSAAFGSGTSREAAVTGSSRGRSARDAAGVLGVPRAGSLQRGRSDEARDLATGRLAVVPDSRRNGTFPPVTIIQVAFCALPVVG
>NC_010511.1|WP_018262010.1|1934363_1934567_-|hypothetical-protein
MTTLTHRSFARPAAPLAARLRAAAGRLLGLVALVPLALVLRERPAAVLAAIPGGRGQRDLGFGLGRR
>NC_010511.1|WP_012331624.1|1933081_1934350_+|glycosyltransferase-family-4-protein
MDVVLILDHGHVNGGQAKVALDSALGLAARGHRVDVFAAVAPVDPRLSAAGIRVTCLDQPDIATASSKLAFAGQMLWNRPAARALAGLLAGRDPGRTIVHVHAFAKALSPSIFAAIRRARLPALYTMHEFFLVCPNGGFYDYRRHAICRRAPLSGACIATNCDMRSYPRKAMRLARQVLLEKLARWPEVVRDVVTISALQEAAVAPHLPPGLTLHRVDNPIAVPDPGPKPAGPPGPLTYVGRLSTEKGVLLFAEAARRAGVPAVFVGDGPEAETLRGRYPEARLLGWRDAAGVAEALRAASALVFPSIWYEGQPLTVYEALARGTPVVVSDACAGREAVADGETGYWFPSGDAAALAARLTRLQDPAVLARLGAEAHRRYWAAPLTLERHCARLEEVYGLVLQRRAAGLAAPAPGARLQPAA
>NC_010511.1|WP_012331623.1|1931717_1932983_-|glycosyltransferase
MHVAILTNFCLPRGGGEKVAIESARGLAEAGLRVTFLHGVEGPADPLLDHPGIRRVGLGLADVWDQPAWRGARDGIWNRAAARRLAAALAALRPDCLHLHNWTRSLSPAVLPVLGASGVPVAVTLHDYFLVCPNGVYYRFDRAEPCSLDPLGARCLAAACDPQSRAHKAVRAARAAATRLALRGLRDRPIDLVHVCDASRARLAPMLPEGPFRHHRIDNPVRVDPHPPADPARGDAVAFVGRLTREKGADLVAAAARAAGMPALFIGDGPLAGELAAMPGAEVLGWRAPGEVEALLRARARAVVAPSRWLETGPLTVYEALACGIPAVASNRAGAAERIVPGETGFVTRPEVDLLARVFHDLADDTLVRRMGRAAHARYWAAPTTLASHAAASARLYAALIARGRAAPATARAPSFQRSAV
>NC_010511.1|WP_012331622.1|1930228_1931644_-|DegQ-family-serine-endoprotease
MRCPMRLALVAALALGPAAALADPAPPTRALPESRAQVQLSFAPIVRKAAPSVVNVYGAHVEKRSANRNAMDEFLRRFFGESGPGGTQERAQRSLGSGVIVDASGLIVTNNHVVENMNEVKVALTDRREFPAEIVLRDPRTDLAVLRIKAPGGIAAMEFGDSEALQVGDFVIAIGNPFGVGQTVTQGIVSALARTQVGSADYQFFIQTDAAINPGNSGGALVDLSGALVGINTAIFSQSGGSHGIGFAIPASMVRAVVETARGGGRIVRRPWLGARLQNVTPDIADSVGLDHPTGVLVAGMLGKSPAEESGLKRGDVILSVDGQPVDDPEAFGYRFALKGISGETKLAVLRGSNRITLPVRLAPAPETRPRDTLKIRTRSPFLGATAVNLSPAVAEELQLDLPADGVVIAEVDGGSIAARAGLQKGDVIVAVNGASVASTRDLDRITRNSLSAWEVTINRGGQQLTSLFSG
>NC_010511.1|WP_012331621.1|1929251_1930124_-|serine-protease
MTDTPTALQAFSQDLAALAARAAPSVVSVQSHRHRASGFVWKPGLVVTADEALAEEGEIAVRAGDGAPLAATLLGRDPSTDVALLRIPRTDLPAAALDPVPVVTGQLAVAVGAAEGAPTVALGLVSRVGPAWRSLRGGEIDVRIDLDLGLRRSGEGGLALDPAGRAIGMVVFGPRRRALVIPAATIGRVAPLLESRGRIPLGYLGLGLQPVRLEDRSVGLMVMQVEPDGPGARADLRQGDVVTAWNGEPLRGLSALQGALGPGSVGSVVTLALRRGGAPLDVALTIGERP
>NC_010511.1|WP_083784650.1|1942723_1943284_+|CRISPR-associated-endonuclease-Cas1
MCGLEGEAAQVYVGVFDTLVRRDDPAFRVSGRSRRPPLDRMNALLSFLYALLGHDCRSALDAHGLDPQVGFLHADRPGRASLALDLMEELRPVLADRLALSLVNRRQLGAEDFRIEEAGGVRLTDDARRTVLGAWQERKREDLRHPFLDETMPLGLVAQMQPHVQAQLLARHLRGDLDGYPAFVWR
>NC_010511.1|WP_012331629.1|1943315_1943606_+|CRISPR-associated-endonuclease-Cas2
MLMLVTDDVNTQTPAGRTRLRRVARACLDVGQRVQNSVFACEVDPAQWTALRDRLVGLIDPQRDSLRFDRLGAEGRRRIAHVGAKPILDLDGPLVF
>NC_010511.1|WP_012331630.1|1944271_1945162_-|LysR-family-transcriptional-regulator
MPLSRLPLNALRAFDVTARLGSMSAAAGELGVTHGAVSRHIKALEAQLGLPLLERLPRAVALTQEGAQLAASLADAFDQIQLAVSRVQPGPLTLSCSATIMMYWLIPRLETFKQAHPAVELRLNISYGEVDFVRDGISVAIRTSMYRPPATARARPLIAEEIGPVCHPDYAARLGLAGPDDLARARILATATRPQAWAEWGRAIGRPDLGIVPQESYGHFYLVIQAAACGLGLALAPRLLVESEIRAGHLAAPFGFTPGPHRLELWIAEHLQARADLRCLVAWIARAMGPDGDRPG
>NC_010511.1|WP_012331631.1|1945440_1946448_+|TRAP-transporter-substrate-binding-protein
MSRLTRRTLLLTGATALAAPHVAWAAEPEFRLKFGNIVSGDHPLNLAMGRVRDRVAQESDGRVRIELFPKNQLGSDADMLSQLRSGALELFAQTGVLMSTLVPVASISGIGFAFPSYDKVWEALDGPLGQHIRGAFAKANLVCLEKSYNHGFRQTTSSTRPIRTPDDFNGFKIRVPPSPLWTSMFKAFGAAPVSIPWAETYSAMQTRIADGLEQPLIGLLVDKMYEVQRSCSLTNHMWDGFWVLANRRAWERLPPDLREMLERAINQEALVQRREVEHMNATLQDRLQSLGLQFHTVANADFRQRLVSSGFYQEWQKRYGDEAWSLLEATTGKLG
>NC_010511.1|WP_012331632.1|1946506_1947295_+|SDR-family-oxidoreductase
MRLQDKVAIVFGAGSAGPGWGNGKAAAALFARNGAEVICVDINRAAAEETAGIIAGEGGRARPAACDVTDSAAVKAVVDEVAARHGRIDVLHNNVGHATMGGPVELDEADWQRALDLNVTGCFLTCKHVLPHMLARRAGAIVNVSSIAAIRYTGYPYAAYYAAKAAVNNFTMGLALQYARDGIRANAIMPGLMNTPLIFQQISGQYRDAEEMVRARDAACPMGRMGTAWDVAKAALFLASDDAAYITGVSLPVDGGLSCRAG
>NC_010511.1|WP_018262003.1|1947291_1948572_+|ribulose-bisphosphate-carboxylase
MSAVQPVPAPPARIEADYLLESVVDPRRAAEIIAGEQSSGTFVPVPGETPELKARAAARIERLDLLDEAVAAPALPSAGIPAGAAARRARLTLSWPLDNLGPSLPNLLATVAGNLFELKPVTGLRLLDIRLPEAFARAYPGPRFGVAGTRRLAGIEGRPLIGTIIKPSVGLDPQQTAALVASLCAGGIDFIKDDELQADGPHCPFDARVRAVMREVRAHRDRTGRAVMVAFNLTGDLDQMRRRHDLLVAEGATCLMASLNSVGLVGMIELGRFSALPIHAHRNGWGYLSRHPLLGWSYVAWQKIWRLAGADHMHVNGLANKFAEPDDSVVASARTCLTPLFPDKPCLAMPVFSSGQSVRQAPGTYRALGGTDLIVTAGGGIMAHPGGPAAGVEALREAWEAAVAGIPLDAYARERPALRDALGAAA
>NC_010511.1|WP_012331634.1|1948568_1949927_+|four-carbon-acid-sugar-kinase-family-protein
MSAPLPDGPLVAFYGDDLTGSSAAMEVLAFAGLETVLFLAPPAPERLAAVSSARAVGIAGMARAAAPAWMDEHLPPVFRLLASLGAPVLHYKVCSTFDSAPHVGSIGRAAEIGARLLAPAWIPMVVADPGMGRYQCFGNLFAMAGEDGHRLDRHPTMARHPVTPMDEADLGRHLARQTALPVGLVDFAATKRGEGGAALARARAAGARIVSLDVLDPETLAAAGRLIWEEGGRPVFGIGSQGFEAALVAHWRRAGLLPPAAPAPRPGAVARIAAVSGSVSPVTQGQIAFARAQGFRVIPLDAARAVDPAAFAREVGRAAEAALAALGEGSDPLVTTAEGPDDPAVARLREAVRAAGAAQEAVDARLGAGLGAILNRVLREGRLGRGVIAGGDTSGRAAAQLGIDALAAIAPLAPGAPLCRALGPEGAPAGLELALKGGQVGRPDFFVAAKGG
>NC_010511.1|WP_012331635.1|1950037_1950865_+|3-oxoacyl-ACP-reductase-FabG
MTGRLADKVALVTGGARGIGLAVARAFAREGAALVIADVNRAGAEAAAAGLAEAGGRAMAVAVDVADPASIAAMVEAILARHGRLDILVNNAGVGGNTPFLETRLEDWNRIIGINLTGAFLVAQACAREMVRGGGGKIVNIASLSGQRGGDGRAAYGAAKAGLELLTKVMAVELSEHGINVNNIAPGAIETEMARFAHDAATRAAYGYLIPMTRYGTPEEIADAAVFLCSDEARYVQGHTLNVDGGFRAAGLMFKRAAPPAAGAAPTLTTNGGTP
>NC_010511.1|WP_012331636.1|1950861_1951881_+|TRAP-transporter-substrate-binding-protein
MTTNPSRRRFAALCATAAIGAALPLRFARAAEFTFKLGTNVPEAHPLNVHARKAAAALLEATGGRVELQLFPNNQLGGDSDMFSQLRSGALECFTLSGVNVLSTLIPAAAISGVGFAFKDYPTLWRALDGRLGAHLRGQIAKSGLVVMDAIWDNGFRQVTTSVRPIVTPADLKGIKIRVPVSALWTSLFKSLGASPTGINFAEVYSALQTRIVDGQENPPAIISAAKLYEVQKYCSLTNHMWDGWWFLMNRRAWAQLSPDLQETFARVVNAAALAEREEVARQNEGLKADLAAKGLIFNEVDPAPFREALTKSGFYKEWKAKFGPEAWAILEETSGELA
>NC_010511.1|WP_043700987.1|1952047_1952902_+|alpha/beta-fold-hydrolase
MTAIARRFADLDGVSLHYLDAGAGDAVVLVHGIPQTSHEWRHVIPRLAGRYRVIAPDLRGLGDSSRPATGYDKKTLAGDLWQLVRGHLGIERFFLVGHDWGGPVAFSLAAQHPEAVRRLAILDVVIPGDGADFSQGGRRWHHAFFRTLDLPEALCAGREHLVLRWLFDHYGQRPTSIPEADQQEYLRTYTQFGAFRAMLAFYRALPVDAEDNREMLARAGKLRMPVLALGGEEGFGRGSECIASLRRVAEDVRGGTVPACGHWIPEEQPERLCDELLRFFGEEP

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Crispr_ID: NC_010511_11

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_010511_11

1943788-1944211

TypeI

Consensus_repeat	Method
ATCGCCCCCTCGCGGGGGCGCGGATTGAAAC	PILER-CR
ATCGCCCCCTCGCGGGGGCGCGGATTGAAAC	CRISPRCasFinder
ATCGCCCCCTCGCGGGGGCGCGGATTGAAAC	CRT

6 spacers

cas2,cas1,cas7b,cas8c,cas5,cas3,cas3HD

The CRISPR arrays of NC_010511_11

>merge|NC_010511|11|1943788-1944211|PILER-CR,CRISPRCasFinder,CRT
ATCGCCCCCTCGCGGGGGCGCGGATTGAATCCGGGTTTTTGCCCCCAACCACCCCGACCTGTCGAATCGCCCCCTCGCGGGGGCGCGGATTGAAACGCCTGCTGCTACCCTCTCTGCGCCGAGGCCATCCATCGCCCCCTCGCGGGGGCGCGGATTGAAACATATGAACAACGGTTGGGCACTCAACAATGTCGACATCGCCCCCTCGCGGGGGCGCGGATTGAAACAAGGCGACCGTGCCCGCGATCATCGAGGTGCGGTGATCGCCCCCTCGCGGGGGCGTGGATTGAAACGCCGTCGGCGCCTGGTCGCTGCCCGGCGACACGCATCGCCCCCTCGCGGGGGCGCGGATTGAAACAACGGGCGCGCCCCGCGTTACCGGGCGCACGCCCATTGCCCCCCTGGCGGGGGCGCCAATGGACAC

>NC_010511|11|1|1943788-1944145|PILER-CR
ATCGCCCCCTCGCGGGGGCGCGGATTGAATC	CGGGTTTTTGCCCCCAACCACCCCGACCTGTCGA
ATCGCCCCCTCGCGGGGGCGCGGATTGAAAC	GCCTGCTGCTACCCTCTCTGCGCCGAGGCCATCC
ATCGCCCCCTCGCGGGGGCGCGGATTGAAAC	ATATGAACAACGGTTGGGCACTCAACAATGTCGAC
ATCGCCCCCTCGCGGGGGCGCGGATTGAAAC	AAGGCGACCGTGCCCGCGATCATCGAGGTGCGGTG
ATCGCCCCCTCGCGGGGGCGTGGATTGAAAC	GCCGTCGGCGCCTGGTCGCTGCCCGGCGACACGC
ATCGCCCCCTCGCGGGGGCGCGGATTGAAAC

>NC_010511|11|11|1943788-1944211|CRISPRCasFinder
ATCGCCCCCTCGCGGGGGCGCGGATTGAATC	CGGGTTTTTGCCCCCAACCACCCCGACCTGTCGA
ATCGCCCCCTCGCGGGGGCGCGGATTGAAAC	GCCTGCTGCTACCCTCTCTGCGCCGAGGCCATCC
ATCGCCCCCTCGCGGGGGCGCGGATTGAAAC	ATATGAACAACGGTTGGGCACTCAACAATGTCGAC
ATCGCCCCCTCGCGGGGGCGCGGATTGAAAC	AAGGCGACCGTGCCCGCGATCATCGAGGTGCGGTG
ATCGCCCCCTCGCGGGGGCGTGGATTGAAAC	GCCGTCGGCGCCTGGTCGCTGCCCGGCGACACGC
ATCGCCCCCTCGCGGGGGCGCGGATTGAAAC	AACGGGCGCGCCCCGCGTTACCGGGCGCACGCCCA
TTGCCCCCCTGGCGGGGGCGCCAATGGACAC

>NC_010511|11|1|1943788-1944211|CRT
ATCGCCCCCTCGCGGGGGCGCGGATTGAATC	CGGGTTTTTGCCCCCAACCACCCCGACCTGTCGA
ATCGCCCCCTCGCGGGGGCGCGGATTGAAAC	GCCTGCTGCTACCCTCTCTGCGCCGAGGCCATCC
ATCGCCCCCTCGCGGGGGCGCGGATTGAAAC	ATATGAACAACGGTTGGGCACTCAACAATGTCGAC
ATCGCCCCCTCGCGGGGGCGCGGATTGAAAC	AAGGCGACCGTGCCCGCGATCATCGAGGTGCGGTG
ATCGCCCCCTCGCGGGGGCGTGGATTGAAAC	GCCGTCGGCGCCTGGTCGCTGCCCGGCGACACGC
ATCGCCCCCTCGCGGGGGCGCGGATTGAAAC	AACGGGCGCGCCCCGCGTTACCGGGCGCACGCCCA
TTGCCCCCCTGGCGGGGGCGCCAATGGACAC

Protein	Signature genes	Signature genes Name	Protein_function
NC_010511.1\|WP_012331632.1\|1946506_1947295_+\|SDR-family-oxidoreductase	unknown	unknown	gnl\|CDD\|235546
NC_010511.1\|WP_043700754.1\|1936205_1937411_+\|IS30-family-transposase	unknown	unknown	gnl\|CDD\|225382
NC_010511.1\|WP_012331629.1\|1943315_1943606_+\|CRISPR-associated-endonuclease-Cas2	cas2	cd09725_cas2_CAS-I:CAS-II:CAS-III:CAS-V	gnl\|CDD\|187856
NC_010511.1\|WP_012331628.1\|1941562_1942642_+\|type-I-C-CRISPR-associated-protein-Cas7/Csd2	cas7b	pfam05107_cas7b_CAS-I-B:CAS-I-C	gnl\|CDD\|377458
NC_010511.1\|WP_012331630.1\|1944271_1945162_-\|LysR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|182990
NC_010511.1\|WP_012331631.1\|1945440_1946448_+\|TRAP-transporter-substrate-binding-protein	unknown	unknown	gnl\|CDD\|224553
NC_010511.1\|WP_018262003.1\|1947291_1948572_+\|ribulose-bisphosphate-carboxylase	unknown	unknown	gnl\|CDD\|173972
NC_010511.1\|WP_012331638.1\|1952905_1953781_-\|3-keto-5-aminohexanoate-cleavage-protein	unknown	unknown	gnl\|CDD\|377562
NC_010511.1\|WP_043700987.1\|1952047_1952902_+\|alpha/beta-fold-hydrolase	unknown	unknown	gnl\|CDD\|235135
NC_010511.1\|WP_012331635.1\|1950037_1950865_+\|3-oxoacyl-ACP-reductase-FabG	unknown	unknown	gnl\|CDD\|235500
NC_010511.1\|WP_050777472.1\|1937434_1938583_+\|hypothetical-protein	cas3	COG1203_cas3_CAS-I	gnl\|CDD\|224124
NC_010511.1\|WP_012331634.1\|1948568_1949927_+\|four-carbon-acid-sugar-kinase-family-protein	unknown	unknown	gnl\|CDD\|225930
NC_010511.1\|WP_012331636.1\|1950861_1951881_+\|TRAP-transporter-substrate-binding-protein	unknown	unknown	gnl\|CDD\|270321
NC_010511.1\|WP_012331627.1\|1939767_1941570_+\|type-I-C-CRISPR-associated-protein-Cas8c/Csd1	cas8c	cd09757_cas8c_CAS-I-C	gnl\|CDD\|378245
NC_010511.1\|WP_018262010.1\|1934363_1934567_-\|hypothetical-protein	unknown	unknown	unknown
NC_010511.1\|WP_012331639.1\|1953892_1954618_+\|alpha/beta-fold-hydrolase	unknown	unknown	gnl\|CDD\|131480
NC_010511.1\|WP_083784650.1\|1942723_1943284_+\|CRISPR-associated-endonuclease-Cas1	cas1	cd09721_cas1_CAS-I-C	gnl\|CDD\|188360
NC_010511.1\|WP_043700984.1\|1939090_1939771_+\|type-I-C-CRISPR-associated-protein-Cas5	cas5	cd09752_cas5_CAS-I-C	gnl\|CDD\|187534
NC_010511.1\|WP_050777471.1\|1934812_1936270_+\|CRISPR-associated-endonuclease-Cas3''	cas3HD	cd09641_cas3HD_CAS-I	gnl\|CDD\|350688
NC_010511.1\|WP_012331624.1\|1933081_1934350_+\|glycosyltransferase-family-4-protein	unknown	unknown	gnl\|CDD\|340831

Protein	Function_ID	Function_description	E-value
NC_010511.1\|WP_012331632.1\|1946506_1947295_+\|SDR-family-oxidoreductase	gnl\|CDD\|235546	PRK05653, fabG, 3-oxoacyl-ACP reductase FabG.	9.37799e-77
NC_010511.1\|WP_043700754.1\|1936205_1937411_+\|IS30-family-transposase	gnl\|CDD\|225382	COG2826, Tra8, Transposase and inactivated derivatives, IS30 family [DNA replication, recombination, and repair].	8.01138e-92
NC_010511.1\|WP_012331629.1\|1943315_1943606_+\|CRISPR-associated-endonuclease-Cas2	gnl\|CDD\|187856	cd09725, Cas2_I_II_III, CRISPR/Cas system-associated protein Cas2. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas2 is present in majority of CRISPR/Cas systems along with Cas1; RNAse specific to U-rich regions; Possesses an RRM/ferredoxin fold.	4.45977e-24
NC_010511.1\|WP_012331628.1\|1941562_1942642_+\|type-I-C-CRISPR-associated-protein-Cas7/Csd2	gnl\|CDD\|377458	pfam05107, Cas_Cas7, CRISPR-associated protein Cas7. CRISPR-associated protein Cas7 is one of the components of the type I-B cascade-like antiviral defense complex. In Haloferax volcanii, Cas5, Cas6 and Cas7 form a small complex that aids the stability of CRISPR-derived RNA.	2.34072e-132
NC_010511.1\|WP_012331630.1\|1944271_1945162_-\|LysR-family-transcriptional-regulator	gnl\|CDD\|182990	PRK11139, PRK11139, DNA-binding transcriptional activator GcvA; Provisional.	1.54273e-66
NC_010511.1\|WP_012331631.1\|1945440_1946448_+\|TRAP-transporter-substrate-binding-protein	gnl\|CDD\|224553	COG1638, DctP, TRAP-type C4-dicarboxylate transport system, periplasmic component [Carbohydrate transport and metabolism].	7.07982e-99
NC_010511.1\|WP_018262003.1\|1947291_1948572_+\|ribulose-bisphosphate-carboxylase	gnl\|CDD\|173972	cd08207, RLP_NonPhot, Ribulose bisphosphate carboxylase like proteins from nonphototrophic bacteria. Ribulose bisphosphate carboxylase (Rubisco) plays an important role in the Calvin reductive pentose phosphate pathway. It catalyzes the primary CO2 fixation step. Rubisco is activated by carbamylation of an active site lysine, stabilized by a divalent cation, which then catalyzes the proton abstraction from the substrate ribulose 1,5 bisphosphate (RuBP) and leads to the formation of two molecules of 3-phosphoglycerate. Members of the Rubisco family can be divided into 4 subgroups, Form I-IV, which differ in their taxonomic distribution and subunit composition. Form I-III have Rubisco activity, while Form IV, also called Rubisco-like proteins (RLP), are missing critical active site residues and therefore do not catalyze CO2 fixation. They are believed to utilize a related enzymatic mechanism, but have divergent functions. The specific function of this subgroup is unknown.	0
NC_010511.1\|WP_012331638.1\|1952905_1953781_-\|3-keto-5-aminohexanoate-cleavage-protein	gnl\|CDD\|377562	pfam05853, BKACE, beta-keto acid cleavage enzyme. BKACE, beta-keto acid cleavage enzyme plays, a role in lysine degradation. In certain instances it catalyzes the conversion of 3-keto-5-aminohexanoate and acetyl-CoA into acetoacetate and 3-aminobutyryl-CoA. The family is found to have at least 14 slightly different potential new enzymatic activities, all of which can therefore be designated as beta-keto acid cleavage enzymes.	3.25059e-63
NC_010511.1\|WP_043700987.1\|1952047_1952902_+\|alpha/beta-fold-hydrolase	gnl\|CDD\|235135	PRK03592, PRK03592, haloalkane dehalogenase; Provisional.	5.98733e-37
NC_010511.1\|WP_012331635.1\|1950037_1950865_+\|3-oxoacyl-ACP-reductase-FabG	gnl\|CDD\|235500	PRK05557, fabG, 3-ketoacyl-(acyl-carrier-protein) reductase; Validated.	4.39171e-89
NC_010511.1\|WP_012331634.1\|1948568_1949927_+\|four-carbon-acid-sugar-kinase-family-protein	gnl\|CDD\|225930	COG3395, COG3395, Uncharacterized protein conserved in bacteria [Function unknown].	3.01833e-62
NC_010511.1\|WP_012331636.1\|1950861_1951881_+\|TRAP-transporter-substrate-binding-protein	gnl\|CDD\|270321	cd13603, PBP2_TRAP_Siap_TeaA_like, Substrate-binding domain of a sialic acid binding Tripartite ATP-independent Periplasmic transport system (SiaP) and related proteins; the type 2 periplasmic-binding protein fold. This subfamily includes the periplasmic-binding component of TRAP transport systems such as SiaP (a sialic acid binding virulence factor), TeaA (an ectoine binding protein), and an uncharacterized TM0322 from hyperthermophilic bacterium Thermotoga maritima. TRAP transporters are a large family of solute transporters ubiquitously found in bacteria and archaea. They are comprised of a periplasmic substrate-binding protein (SBP) and two unequally sized integral membrane components: a large transmembrane subunit involved in the translocation process and a smaller membrane of unknown function. The driving force of TRAP transporters is provided by electrochemical ion gradients (either protons or sodium ions) across the cytoplasmic membrane, rather than ATP hydrolysis. This substrate-binding domain belongs to the type 2 periplasmic binding fold protein superfamily (PBP2). The PBP2 proteins are typically comprised of two globular subdomains connected by a flexible hinge and bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap.	4.49179e-111
NC_010511.1\|WP_012331627.1\|1939767_1941570_+\|type-I-C-CRISPR-associated-protein-Cas8c/Csd1	gnl\|CDD\|378245	pfam09709, Cas_Csd1, CRISPR-associated protein (Cas_Csd1). CRISPR loci appear to be mobile elements with a wide host range. This entry represents proteins that tend to be found near CRISPR repeats. The species range, so far, is exclusively bacterial and mesophilic, although CRISPR loci are particularly common among the archaea and thermophilic bacteria. Clusters of short DNA repeats with nonhomologous spacers, which are found at regular intervals in the genomes of phylogenetically distinct prokaryotic species, comprise a family with recognisable features. This family is known as CRISPR (short for Clustered, Regularly Interspaced Short Palindromic Repeats). A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins.	0
NC_010511.1\|WP_050777472.1\|1937434_1938583_+\|hypothetical-protein	gnl\|CDD\|224124	COG1203, COG1203, CRISPR-associated helicase Cas3 [Defense mechanisms].	7.02044e-25
NC_010511.1\|WP_012331639.1\|1953892_1954618_+\|alpha/beta-fold-hydrolase	gnl\|CDD\|131480	TIGR02427, b-ketoadipate_enol-lactone_hydrolase, 3-oxoadipate enol-lactonase. Members of this family are 3-oxoadipate enol-lactonase. Note that the substrate is known as 3-oxoadipate enol-lactone, 2-oxo-2,3-dihydrofuran-5-acetate, 4,5-Dihydro-5-oxofuran-2-acetate, and 5-oxo-4,5-dihydrofuran-2-acetate. The enzyme the catalyzes the fourth step in the protocatechuate degradation to beta-ketoadipate and then to succinyl-CoA and acetyl-CoA. 4-hydroxybenzoate, 3-hydroxybenzoate, and vanillate all can be converted in one step to protocatechuate. This enzyme also acts in catechol degradation. In genomes that catabolize both catechol and protocatechuate, two forms of this enzyme may be found. All members of the seed alignment for this model were chosen from within protocatechuate degradation operons of at least three genes of the pathway, from genomes with the complete pathway through beta-ketoadipate. [Energy metabolism, Other].	1.10492e-16
NC_010511.1\|WP_083784650.1\|1942723_1943284_+\|CRISPR-associated-endonuclease-Cas1	gnl\|CDD\|188360	TIGR03640, cas1_DVULG, CRISPR-associated endonuclease Cas1, subtype I-C/DVULG. The CRISPR-associated protein Cas1 is virtually universal to CRISPR systems. CRISPR, an acronym for Clustered Regularly Interspaced Short Palindromic Repeats, is prokaryotic immunity system for foreign DNA, mostly from phage. CRISPR systems belong to different subtypes, distinguished by both nature of the repeats, the makeup of the cohort of associated Cas proteins, and by molecular phylogeny within the more universal Cas proteins such as this one. This model is of type EXCEPTION and provides more specific information than the EQUIVALOG model TIGR00287. It describes the Cas1 protein particular to the DVULG subtype of CRISPR/Cas system.	1.36797e-106
NC_010511.1\|WP_043700984.1\|1939090_1939771_+\|type-I-C-CRISPR-associated-protein-Cas5	gnl\|CDD\|187534	cd09752, Cas5_I-C, CRISPR/Cas system-associated RAMP superfamily protein Cas5. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas5 is a RAMP superfamily protein; Subunit of the Cascade complex; in subtype I-C this protein might be the endoribonuclease that generates crRNAs; also known as DevS family.	1.15785e-102
NC_010511.1\|WP_050777471.1\|1934812_1936270_+\|CRISPR-associated-endonuclease-Cas3''	gnl\|CDD\|350688	cd17930, DEXHc_cas3, DEXH/Q-box helicase domain of Cas3. CRISPR-associated (Cas) 3 is a nuclease-helicase responsible for degradation of dsDNA. The two enzymatic units of Cas3, a histidine-aspartate (HD) nuclease and a Superfamily 2 (SF2) helicase, may be expressed from separate genes as Cas3' (SF2 helicase) and Cas3'' (HD nuclease) or may be fused as a single HD-SF2 polypeptide. The nucleolytic activity of most Cas3 enzymes is transition metal ion-dependent. Cas3 is a member of the DEAD-like helicase superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.	1.79409e-41
NC_010511.1\|WP_012331624.1\|1933081_1934350_+\|glycosyltransferase-family-4-protein	gnl\|CDD\|340831	cd03801, GT4_PimA-like, phosphatidyl-myo-inositol mannosyltransferase. This family is most closely related to the GT4 family of glycosyltransferases and named after PimA in Propionibacterium freudenreichii, which is involved in the biosynthesis of phosphatidyl-myo-inositol mannosides (PIM) which are early precursors in the biosynthesis of lipomannans (LM) and lipoarabinomannans (LAM), and catalyzes the addition of a mannosyl residue from GDP-D-mannose (GDP-Man) to the position 2 of the carrier lipid phosphatidyl-myo-inositol (PI) to generate a phosphatidyl-myo-inositol bearing an alpha-1,2-linked mannose residue (PIM1). Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate residue. This group of glycosyltransferases is most closely related to the previously defined glycosyltransferase family 1 (GT1). The members of this family may transfer UDP, ADP, GDP, or CMP linked sugars. The diverse enzymatic activities among members of this family reflect a wide range of biological functions. The protein structure available for this family has the GTB topology, one of the two protein topologies observed for nucleotide-sugar-dependent glycosyltransferases. GTB proteins have distinct N- and C- terminal domains each containing a typical Rossmann fold. The two domains have high structural homology despite minimal sequence homology. The large cleft that separates the two domains includes the catalytic center and permits a high degree of flexibility. The members of this family are found mainly in certain bacteria and archaea.	1.44856e-36

>NC_010511.1|WP_012331629.1|1943315_1943606_+|CRISPR-associated-endonuclease-Cas2
MLMLVTDDVNTQTPAGRTRLRRVARACLDVGQRVQNSVFACEVDPAQWTALRDRLVGLIDPQRDSLRFDRLGAEGRRRIAHVGAKPILDLDGPLVF
>NC_010511.1|WP_083784650.1|1942723_1943284_+|CRISPR-associated-endonuclease-Cas1
MCGLEGEAAQVYVGVFDTLVRRDDPAFRVSGRSRRPPLDRMNALLSFLYALLGHDCRSALDAHGLDPQVGFLHADRPGRASLALDLMEELRPVLADRLALSLVNRRQLGAEDFRIEEAGGVRLTDDARRTVLGAWQERKREDLRHPFLDETMPLGLVAQMQPHVQAQLLARHLRGDLDGYPAFVWR
>NC_010511.1|WP_012331628.1|1941562_1942642_+|type-I-C-CRISPR-associated-protein-Cas7/Csd2
MADAGLQRRHDFVLYFDVTNGNPNGDPDAGNMPRMDPETGHGLVSDVCLKRKVRNYVEMAAEADGRDPIRNRIYVTEGAVLNEKHREAYLALRPDDPKARTDKKLTPKSDEEAVLIRRFMCDNFFDIRTFGAVLSTGINAGQVRGPVQVSFARSVEPVLPLEVSITRMAATNEAERNERQDGEDKAGKRGDKRTMGRKHMAATNEAERNERQDGDDEAEKRGDKRTMGRKHIVPYGLYRAHGYVSAPLASHPVKGTGFSDGDLALLFEALRNMFEHDRSATRGEMATRRLVVFRHASALGNAPAQSLFERVRTLRAHKGSVHEIGAPGTDNWPPARSFADYAITVDREGLPQGIEVTEW
>NC_010511.1|WP_012331627.1|1939767_1941570_+|type-I-C-CRISPR-associated-protein-Cas8c/Csd1
MTMLQALDRYYDRLERRGEVVMPGWSTEPLGLVLELAEDGTPLGLADRLTARGKPQLDRVPKWFSRSGTGSTPFFLWDNLAYALGLGTKDPAKTARDHAAFRDLHLRELAGERDPALAALRRFVEAWVPDPEAARALGLQSRHMALNLGFRLRGETVPLHHRPAAAAHVERLRAAHEGGPEGFCLVRGARLPLVRLHPKVKGIDGGAAAEIPLVSFNQDAFTSYGHDQGFNAPTSAAAAFRYGAALNALLQRGGPNRLRIADSTVAFWADARAYDASVAEPIALAAEDIFGDALRDGPGPAGTTDARETQALREALVTVAEARAAPDLRPDLMENVPFFVLGLAPNMARVAVRYWLAGTFGSFRRALDAHAAALAIEPKPRGWGAKPPSPARLLLKTTALAEEFDNIPHGLAAEVTRAILENRPYPRTWLAATIARLRAGDDPGRGWHAAAIKACLNRRSEREMLPVALDPAHTDPAYQLGRLFAVLEAAQRTALPGVNTTIGDRWYAAASSTPARVFGPLLRSLKTHVADARKRGLGGWIEPKVAEIMQRLPPDLPRVLSLEAQGRFAVGYYHERGTRPEKKTDSPTTTGTDPEETPHG
>NC_010511.1|WP_043700984.1|1939090_1939771_+|type-I-C-CRISPR-associated-protein-Cas5
MTYGVRLHVWGERALFTRPETKVERVSYDVPTPSAARGILEAIHWKPAIVWRIDRIHVLKPIRFASVRRNEVGAKASTALALRAMRSGTLAGLGLSAEIERQQRAATMLVDVGYVIEAHLEMTARAGDDAPVKHICMFNRRAAAGQCFHRPCLGTRECPAEFALIPDGAPLPASSLPAEERERELGWMLYDIDFRPDRNEARFFRARLSKGILDVRACLAANEVVS
>NC_010511.1|WP_050777472.1|1937434_1938583_+|hypothetical-protein
MLLPCLAALEELTGNYGATVVLCTATQPAVRVRDGALRERFRPVDHGLPIGADRELAPRPERLADEVRRVTVEVLPEPIGDEVVAARFEAQKQMLCIVNSRAHARALFARIRGLPGAFYLTTLMCPAHRRAVLAEIKARLEDGRPVRLVATSLVEAGIDFSFPEVWRAEAGLDQIAQAAGRCNRNGELHPALGRVVVFTPAAHRPPRSLAAFQQAARPVLRDHPDPLGPDAIAAYFRLLYAERGLAELDAAEIDGQAGILAAFGRHGLERGFPFESVARAFRLIDETMVPVVVPWDAEAVQALAEVAGMERPTGEALRRLHPYTVGIPRQAHAGWCATREIVPVGPACGEVLTRFATMDLYDATIGIDLWATAARDGEADAP
>NC_010511.1|WP_043700754.1|1936205_1937411_+|IS30-family-transposase
MAPSHLSPSSKSPSARYLSLAEREEIAILQAQGHGVRDVARRLGRAASTISRELRRNAATRSGGLDYRATTAQWHAERAARRPKPAKLAGNAALRTYVQERLAGTVATPGGSALPGPSVAWKGRRHGRRQSRRWGRSWSPQQIAERLRLDFPGDTTMRISHEAIYQALYIQGRGALKRELTACLRTGRALRVPRARSLGRGRSFVTPEVLISERPPEVEDRAVPGHWEGDLILGLKSSAIGTLVERTTRFTMLLHLPPMDGHGVTPRAKNGPALAGHGAQAVREAIAGTIARLPEQLRRSLTWDQGTEMAEHARLRIDAGLQVYFCDPRSPWQRGTNENTNGLLRQYFPKGTDLSAHSANDLAAVAAALNSRPRKTLNWKTPAEALDAVLAAVQDGVATTA
>NC_010511.1|WP_050777471.1|1934812_1936270_+|CRISPR-associated-endonuclease-Cas3''
MSSVLYAHSKPGRPEAEWEPLAVHARWTGRFAAHFGRAFGCAGLARAQGLLHDTGKASQEFQDYLCALRARGGDHSTWGAQRADELYGRVVGRMLAACIAGHHGGLPDGEALRRRLAQAQNDASRWRELIIPLAPEVIASKRCFAPPARERFEQCPDALARRRAFTKAFLIRMLFSCLVDADFRATERFMADGRPRARVRTRLRDLDRQLTAHLRCKQADAKPTAINALRAEILAHAVAKATCTPGLFTLTVPTGGGKTLTSLAFALAHAERYGKRRVIHVAPFTAIVEQTADAIRTAVGNPGAILEHHANLDEEALARRLAEDGGDERDGLGPLRRAAATWDAPIVVTTAVQFFESLFANRPSRCRKLHNLANSVIILDEAQTVDSSGRRNGLAEGGCDGRSAAFGSGTSREAAVTGSSRGRSARDAAGVLGVPRAGSLQRGRSDEARDLATGRLAVVPDSRRNGTFPPVTIIQVAFCALPVVG
>NC_010511.1|WP_018262010.1|1934363_1934567_-|hypothetical-protein
MTTLTHRSFARPAAPLAARLRAAAGRLLGLVALVPLALVLRERPAAVLAAIPGGRGQRDLGFGLGRR
>NC_010511.1|WP_012331624.1|1933081_1934350_+|glycosyltransferase-family-4-protein
MDVVLILDHGHVNGGQAKVALDSALGLAARGHRVDVFAAVAPVDPRLSAAGIRVTCLDQPDIATASSKLAFAGQMLWNRPAARALAGLLAGRDPGRTIVHVHAFAKALSPSIFAAIRRARLPALYTMHEFFLVCPNGGFYDYRRHAICRRAPLSGACIATNCDMRSYPRKAMRLARQVLLEKLARWPEVVRDVVTISALQEAAVAPHLPPGLTLHRVDNPIAVPDPGPKPAGPPGPLTYVGRLSTEKGVLLFAEAARRAGVPAVFVGDGPEAETLRGRYPEARLLGWRDAAGVAEALRAASALVFPSIWYEGQPLTVYEALARGTPVVVSDACAGREAVADGETGYWFPSGDAAALAARLTRLQDPAVLARLGAEAHRRYWAAPLTLERHCARLEEVYGLVLQRRAAGLAAPAPGARLQPAA
>NC_010511.1|WP_012331630.1|1944271_1945162_-|LysR-family-transcriptional-regulator
MPLSRLPLNALRAFDVTARLGSMSAAAGELGVTHGAVSRHIKALEAQLGLPLLERLPRAVALTQEGAQLAASLADAFDQIQLAVSRVQPGPLTLSCSATIMMYWLIPRLETFKQAHPAVELRLNISYGEVDFVRDGISVAIRTSMYRPPATARARPLIAEEIGPVCHPDYAARLGLAGPDDLARARILATATRPQAWAEWGRAIGRPDLGIVPQESYGHFYLVIQAAACGLGLALAPRLLVESEIRAGHLAAPFGFTPGPHRLELWIAEHLQARADLRCLVAWIARAMGPDGDRPG
>NC_010511.1|WP_012331631.1|1945440_1946448_+|TRAP-transporter-substrate-binding-protein
MSRLTRRTLLLTGATALAAPHVAWAAEPEFRLKFGNIVSGDHPLNLAMGRVRDRVAQESDGRVRIELFPKNQLGSDADMLSQLRSGALELFAQTGVLMSTLVPVASISGIGFAFPSYDKVWEALDGPLGQHIRGAFAKANLVCLEKSYNHGFRQTTSSTRPIRTPDDFNGFKIRVPPSPLWTSMFKAFGAAPVSIPWAETYSAMQTRIADGLEQPLIGLLVDKMYEVQRSCSLTNHMWDGFWVLANRRAWERLPPDLREMLERAINQEALVQRREVEHMNATLQDRLQSLGLQFHTVANADFRQRLVSSGFYQEWQKRYGDEAWSLLEATTGKLG
>NC_010511.1|WP_012331632.1|1946506_1947295_+|SDR-family-oxidoreductase
MRLQDKVAIVFGAGSAGPGWGNGKAAAALFARNGAEVICVDINRAAAEETAGIIAGEGGRARPAACDVTDSAAVKAVVDEVAARHGRIDVLHNNVGHATMGGPVELDEADWQRALDLNVTGCFLTCKHVLPHMLARRAGAIVNVSSIAAIRYTGYPYAAYYAAKAAVNNFTMGLALQYARDGIRANAIMPGLMNTPLIFQQISGQYRDAEEMVRARDAACPMGRMGTAWDVAKAALFLASDDAAYITGVSLPVDGGLSCRAG
>NC_010511.1|WP_018262003.1|1947291_1948572_+|ribulose-bisphosphate-carboxylase
MSAVQPVPAPPARIEADYLLESVVDPRRAAEIIAGEQSSGTFVPVPGETPELKARAAARIERLDLLDEAVAAPALPSAGIPAGAAARRARLTLSWPLDNLGPSLPNLLATVAGNLFELKPVTGLRLLDIRLPEAFARAYPGPRFGVAGTRRLAGIEGRPLIGTIIKPSVGLDPQQTAALVASLCAGGIDFIKDDELQADGPHCPFDARVRAVMREVRAHRDRTGRAVMVAFNLTGDLDQMRRRHDLLVAEGATCLMASLNSVGLVGMIELGRFSALPIHAHRNGWGYLSRHPLLGWSYVAWQKIWRLAGADHMHVNGLANKFAEPDDSVVASARTCLTPLFPDKPCLAMPVFSSGQSVRQAPGTYRALGGTDLIVTAGGGIMAHPGGPAAGVEALREAWEAAVAGIPLDAYARERPALRDALGAAA
>NC_010511.1|WP_012331634.1|1948568_1949927_+|four-carbon-acid-sugar-kinase-family-protein
MSAPLPDGPLVAFYGDDLTGSSAAMEVLAFAGLETVLFLAPPAPERLAAVSSARAVGIAGMARAAAPAWMDEHLPPVFRLLASLGAPVLHYKVCSTFDSAPHVGSIGRAAEIGARLLAPAWIPMVVADPGMGRYQCFGNLFAMAGEDGHRLDRHPTMARHPVTPMDEADLGRHLARQTALPVGLVDFAATKRGEGGAALARARAAGARIVSLDVLDPETLAAAGRLIWEEGGRPVFGIGSQGFEAALVAHWRRAGLLPPAAPAPRPGAVARIAAVSGSVSPVTQGQIAFARAQGFRVIPLDAARAVDPAAFAREVGRAAEAALAALGEGSDPLVTTAEGPDDPAVARLREAVRAAGAAQEAVDARLGAGLGAILNRVLREGRLGRGVIAGGDTSGRAAAQLGIDALAAIAPLAPGAPLCRALGPEGAPAGLELALKGGQVGRPDFFVAAKGG
>NC_010511.1|WP_012331635.1|1950037_1950865_+|3-oxoacyl-ACP-reductase-FabG
MTGRLADKVALVTGGARGIGLAVARAFAREGAALVIADVNRAGAEAAAAGLAEAGGRAMAVAVDVADPASIAAMVEAILARHGRLDILVNNAGVGGNTPFLETRLEDWNRIIGINLTGAFLVAQACAREMVRGGGGKIVNIASLSGQRGGDGRAAYGAAKAGLELLTKVMAVELSEHGINVNNIAPGAIETEMARFAHDAATRAAYGYLIPMTRYGTPEEIADAAVFLCSDEARYVQGHTLNVDGGFRAAGLMFKRAAPPAAGAAPTLTTNGGTP
>NC_010511.1|WP_012331636.1|1950861_1951881_+|TRAP-transporter-substrate-binding-protein
MTTNPSRRRFAALCATAAIGAALPLRFARAAEFTFKLGTNVPEAHPLNVHARKAAAALLEATGGRVELQLFPNNQLGGDSDMFSQLRSGALECFTLSGVNVLSTLIPAAAISGVGFAFKDYPTLWRALDGRLGAHLRGQIAKSGLVVMDAIWDNGFRQVTTSVRPIVTPADLKGIKIRVPVSALWTSLFKSLGASPTGINFAEVYSALQTRIVDGQENPPAIISAAKLYEVQKYCSLTNHMWDGWWFLMNRRAWAQLSPDLQETFARVVNAAALAEREEVARQNEGLKADLAAKGLIFNEVDPAPFREALTKSGFYKEWKAKFGPEAWAILEETSGELA
>NC_010511.1|WP_043700987.1|1952047_1952902_+|alpha/beta-fold-hydrolase
MTAIARRFADLDGVSLHYLDAGAGDAVVLVHGIPQTSHEWRHVIPRLAGRYRVIAPDLRGLGDSSRPATGYDKKTLAGDLWQLVRGHLGIERFFLVGHDWGGPVAFSLAAQHPEAVRRLAILDVVIPGDGADFSQGGRRWHHAFFRTLDLPEALCAGREHLVLRWLFDHYGQRPTSIPEADQQEYLRTYTQFGAFRAMLAFYRALPVDAEDNREMLARAGKLRMPVLALGGEEGFGRGSECIASLRRVAEDVRGGTVPACGHWIPEEQPERLCDELLRFFGEEP
>NC_010511.1|WP_012331638.1|1952905_1953781_-|3-keto-5-aminohexanoate-cleavage-protein
MPVWIEAALNGPWTRARQPRMPLTVAECVADGVACARAGAAIIHVHAYDPATGRQNDDPEVYAAIIEGIRAVEDVIVYPTLPFIQSAEAFRPGALEARFAAVEALGRRGLLEWGVVDPGSTHLATAEEAARGEPGSVYLNPGEHVLRGLALAARFGAVPSYAIYEPGFLRLGAILARAVPGCPPPVYRFMFSDRFTFGFPPAEYALDAYLRLLASAAPGSPWMVAGLGVDVRPLAAEAVARGGHVRVGLEDAPFGTETGNPALVEEMAGLVARAGGRPATAAEVRGARAGR
>NC_010511.1|WP_012331639.1|1953892_1954618_+|alpha/beta-fold-hydrolase
MIDLVLLPGLLNDADLWRDQVEALSDIARIRVGDITRGDTIEAVADQVLAEAPQAFALAGFSLGGIVAQEILRRAAARVTRLALLDTTIAPDGPERAASRRALDRAARVPGRFHGFGDRLLATYLHPSHRGDAEIVGRIRAMTERLGPEIFRRQNGLERRDGSALLRGWRKPLLILCGEADAVTPLADHRAMAALAPGARLVVVPESGHLTPIEQPGAVSRALRDWLAEAGAPLPGPPAIA

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Crispr_ID: NC_010511_12

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_010511_12

2469416-2469503

Orphan

Consensus_repeat	Method
ATCCCTTCGGGATGGCGGATGTGGG	CRISPRCasFinder

1 spacers

The CRISPR arrays of NC_010511_12

>merge|NC_010511|12|2469416-2469503|CRISPRCasFinder
ATCCCTTCGGGATGGCGGATGTGGGATTCGCTCAGGCGCCGCGCGGGCTGGTGATCCGCTTGATCCCTTCGGGGATGGCGGATGTGGG

>NC_010511|12|12|2469416-2469503|CRISPRCasFinder
ATCCCTTCGGGATGGCGGATGTGGG	ATTCGCTCAGGCGCCGCGCGGGCTGGTGATCCGCTTGA
TCCCTTCGGGGATGGCGGATGTGGG

Protein	Signature genes	Signature genes Name	Protein_function
NC_010511.1\|WP_012332084.1\|2467919_2468768_-\|urease-accessory-protein-UreD	unknown	unknown	gnl\|CDD\|223899
NC_010511.1\|WP_012332089.1\|2473340_2473838_-\|signal-peptidase-II	unknown	unknown	gnl\|CDD\|184824
NC_010511.1\|WP_083784800.1\|2479670_2480231_+\|chemotaxis-protein	unknown	unknown	gnl\|CDD\|377318
NC_010511.1\|WP_012332081.1\|2464212_2465940_-\|urease-subunit-alpha	unknown	unknown	gnl\|CDD\|237305
NC_010511.1\|WP_012332087.1\|2470918_2472283_-\|insulinase-family-protein	unknown	unknown	gnl\|CDD\|223685
NC_010511.1\|WP_012332091.1\|2477427_2477682_+\|hypothetical-protein	unknown	unknown	unknown
NC_010511.1\|WP_012332092.1\|2477668_2478634_-\|bifunctional-riboflavin-kinase/FAD-synthetase	unknown	unknown	gnl\|CDD\|235536
NC_010511.1\|WP_012332083.1\|2467222_2467843_-\|urease-subunit-gamma	unknown	unknown	gnl\|CDD\|183886
NC_010511.1\|WP_012332088.1\|2472513_2473194_-\|hypothetical-protein	unknown	unknown	unknown
NC_010511.1\|WP_012332076.1\|2456049_2458338_-\|GAF-domain-containing-protein	unknown	unknown	gnl\|CDD\|226702
NC_010511.1\|WP_012332080.1\|2462284_2463877_-\|ABC-transporter-substrate-binding-protein	unknown	unknown	gnl\|CDD\|173867
NC_010511.1\|WP_012332086.1\|2469558_2470860_-\|insulinase-family-protein	unknown	unknown	gnl\|CDD\|223685
NC_010511.1\|WP_012332093.1\|2479122_2479506_+\|response-regulator	unknown	unknown	gnl\|CDD\|381150
NC_010511.1\|WP_012332079.1\|2461332_2462274_-\|ABC-transporter-permease	unknown	unknown	gnl\|CDD\|223674
NC_010511.1\|WP_012332077.1\|2458823_2460473_-\|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|224048
NC_010511.1\|WP_012332085.1\|2468923_2469361_+\|cupin-domain-containing-protein	unknown	unknown	gnl\|CDD\|226586
NC_010511.1\|WP_012332095.1\|2480231_2481137_-\|TIGR01459-family-HAD-type-hydrolase	unknown	unknown	gnl\|CDD\|319827
NC_010511.1\|WP_012332078.1\|2460469_2461336_-\|ABC-transporter-permease	unknown	unknown	gnl\|CDD\|224094
NC_010511.1\|WP_012332082.1\|2466065_2467199_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|213699
NC_010511.1\|WP_012332090.1\|2474140_2477110_-\|isoleucine--tRNA-ligase	unknown	unknown	gnl\|CDD\|237514

Protein	Function_ID	Function_description	E-value
NC_010511.1\|WP_012332084.1\|2467919_2468768_-\|urease-accessory-protein-UreD	gnl\|CDD\|223899	COG0829, UreH, Urease accessory protein UreH [Posttranslational modification, protein turnover, chaperones].	1.24216e-62
NC_010511.1\|WP_012332089.1\|2473340_2473838_-\|signal-peptidase-II	gnl\|CDD\|184824	PRK14796, PRK14796, lipoprotein signal peptidase; Provisional.	7.93796e-73
NC_010511.1\|WP_012332081.1\|2464212_2465940_-\|urease-subunit-alpha	gnl\|CDD\|237305	PRK13207, ureC, urease subunit alpha; Reviewed.	0
NC_010511.1\|WP_012332087.1\|2470918_2472283_-\|insulinase-family-protein	gnl\|CDD\|223685	COG0612, PqqL, Predicted Zn-dependent peptidases [General function prediction only].	8.48854e-95
NC_010511.1\|WP_083784800.1\|2479670_2480231_+\|chemotaxis-protein	gnl\|CDD\|377318	pfam04344, CheZ, Chemotaxis phosphatase, CheZ. This family represents the bacterial chemotaxis phosphatase, CheZ. This protein forms a dimer characterized by a long four-helix bundle, composed of two helices from each monomer. CheZ dephosphorylates CheY in a reaction that is essential to maintain a continuous chemotactic response to environmental changes. It is thought that CheZ's conserved residue Gln 147 orientates a water molecule for nucleophilic attack at the CheY active site.	7.73731e-05
NC_010511.1\|WP_012332092.1\|2477668_2478634_-\|bifunctional-riboflavin-kinase/FAD-synthetase	gnl\|CDD\|235536	PRK05627, PRK05627, bifunctional riboflavin kinase/FAD synthetase.	1.02149e-121
NC_010511.1\|WP_012332083.1\|2467222_2467843_-\|urease-subunit-gamma	gnl\|CDD\|183886	PRK13192, PRK13192, bifunctional urease subunit gamma/beta; Reviewed.	3.67952e-103
NC_010511.1\|WP_012332076.1\|2456049_2458338_-\|GAF-domain-containing-protein	gnl\|CDD\|226702	COG4251, COG4251, Bacteriophytochrome (light-regulated signal transduction histidine kinase) [Signal transduction mechanisms].	0
NC_010511.1\|WP_012332080.1\|2462284_2463877_-\|ABC-transporter-substrate-binding-protein	gnl\|CDD\|173867	cd08502, PBP2_NikA_DppA_OppA_like_16, The substrate-binding component of an uncharacterized ABC-type nickel/dipeptide/oligopeptide-like import system contains the type 2 periplasmic binding fold. This CD represents the substrate-binding domain of an uncharacterized ATP-binding cassette (ABC) type nickel/dipeptide/oligopeptide-like transporter. The oligopeptide-binding protein OppA and the dipeptide-binding protein DppA show significant sequence similarity to NikA, the initial nickel receptor. The DppA binds dipeptides and some tripeptides and is involved in chemotaxis toward dipeptides, whereas the OppA binds peptides of a wide range of lengths (2-35 amino acid residues) and plays a role in recycling of cell wall peptides, which precludes any involvement in chemotaxis. Most of other periplasmic binding proteins are comprised of only two globular subdomains corresponding to domains I and III of the dipeptide/oligopeptide binding proteins. The structural topology of these domains is most similar to that of the type 2 periplasmic binding proteins (PBP2), which are responsible for the uptake of a variety of substrates such as phosphate, sulfate, polysaccharides, lysine/arginine/ornithine, and histidine. The PBP2 bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap. After binding their specific ligand with high affinity, they can interact with a cognate membrane transport complex comprised of two integral membrane domains and two cytoplasmically located ATPase domains. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis. Besides transport proteins, the PBP2 superfamily includes the ligand-binding domains from ionotropic glutamate receptors, LysR-type transcriptional regulators, and unorthodox sensor proteins involved in signal transduction.	0
NC_010511.1\|WP_012332086.1\|2469558_2470860_-\|insulinase-family-protein	gnl\|CDD\|223685	COG0612, PqqL, Predicted Zn-dependent peptidases [General function prediction only].	1.59261e-81
NC_010511.1\|WP_012332093.1\|2479122_2479506_+\|response-regulator	gnl\|CDD\|381150	cd19923, REC_CheY_CheY3, phosphoacceptor receiver (REC) domain of chemotaxis response regulator CheY3 and similar CheY family proteins. CheY family chemotaxis response regulators (RRs) comprise about 17% of bacterial RRs and almost half of all RRs in archaea. This subfamily contains Vibrio cholerae CheY3, Escherichia coli CheY, and similar CheY family RRs. CheY proteins control bacterial motility and participate in signaling phosphorelays and in protein-protein interactions. CheY RRs contain only the REC domain with no output/effector domain. REC domains function as phosphorylation-mediated switches within response regulators, but some also transfer phosphoryl groups in multistep phosphorelays.	1.47309e-59
NC_010511.1\|WP_012332079.1\|2461332_2462274_-\|ABC-transporter-permease	gnl\|CDD\|223674	COG0601, DppB, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism].	7.00162e-125
NC_010511.1\|WP_012332077.1\|2458823_2460473_-\|ABC-transporter-ATP-binding-protein	gnl\|CDD\|224048	COG1123, COG1123, ATPase components of various ABC-type transport systems, contain duplicated ATPase [General function prediction only].	0
NC_010511.1\|WP_012332085.1\|2468923_2469361_+\|cupin-domain-containing-protein	gnl\|CDD\|226586	COG4101, COG4101, Predicted mannose-6-phosphate isomerase [Carbohydrate transport and metabolism].	3.02056e-55
NC_010511.1\|WP_012332095.1\|2480231_2481137_-\|TIGR01459-family-HAD-type-hydrolase	gnl\|CDD\|319827	cd07525, HAD_like, uncharacterized family of the haloacid dehalogenase-like (HAD) hydrolase superfamily. The haloacid dehalogenase-like (HAD) hydrolases are a large superfamily of diverse enzymes that catalyze carbon or phosphoryl group transfer reactions on a range of substrates, using an active site aspartate in nucleophilic catalysis. Members include 2-L-haloalkanoic acid dehalogenase (C-Cl bond hydrolysis), azetidine hydrolase (C-N bond hydrolysis); phosphonoacetaldehyde hydrolase (C-P bond hydrolysis), phosphoserine phosphatase and phosphomannomutase (CO-P bond hydrolysis), P-type ATPases (PO-P bond hydrolysis) and many others. Members are found in all three kingdoms of life, and most genomes are predicted to contain multiple HAD-like proteins. Members possess a highly conserved alpha/beta core domain, and many also possess a small cap domain, the fold and function of which is variable. HAD hydrolases are sometimes referred to as belonging to the DDDD superfamily of phosphohydrolases.	1.09524e-87
NC_010511.1\|WP_012332078.1\|2460469_2461336_-\|ABC-transporter-permease	gnl\|CDD\|224094	COG1173, DppC, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism].	1.94125e-85
NC_010511.1\|WP_012332082.1\|2466065_2467199_+\|hypothetical-protein	gnl\|CDD\|213699	TIGR02308, T4_RNA_ligase_1, RNA ligase, T4 RnlA family. Members of this family are phage proteins with ATP-dependent RNA ligase activity. Host defense to phage may include cleavage and inactivation of specific tRNA molecules; members of this family act to reverse this RNA damage. The enzyme is adenylated, transiently, on a Lys residue in a motif KXDGSL. [Mobile and extrachromosomal element functions, Prophage functions, Transcription, RNA processing].	9.27143e-27
NC_010511.1\|WP_012332090.1\|2474140_2477110_-\|isoleucine--tRNA-ligase	gnl\|CDD\|237514	PRK13804, ileS, isoleucyl-tRNA synthetase; Provisional.	0

>NC_010511.1|WP_012332085.1|2468923_2469361_+|cupin-domain-containing-protein
MSDLTDSSTCRVVGAGDAFVGKQALTYRPGISAESVGARGIHLQSVNMPPGARAKAHLHEGHETALHVLSGVAGMWYGPRLEHHMWNRAGDYVYIPAGMPHLPYNASRTETVVAVIARTDPNEQESVVLRPDLDALRPAGEDPMA
>NC_010511.1|WP_012332084.1|2467919_2468768_-|urease-accessory-protein-UreD
MSSHPTPSWPRRQRSEGRVALGAGLVAGGTTRLTDLAETGPLRLRLPRVEGAALEGVLLNSAGGLACGDRFAVAAEIGEGADMVLTTTAAEKIYRSDGPVTEIAAELRLGPRARLAWLPQETILYDGARLSRRLTAEIAPDAALTLFEALVFGRSARGETVREGEIRDAWRLARGGRLVYADTLRLDGAVAAHLARPAIAGGARAVATLVHAAPDAESRLDGLRGLIAAAGCAALGVEAGASAWNGLLVLRLLAPESAPLRRAATRILEGFRGLPLPRVWQT
>NC_010511.1|WP_012332083.1|2467222_2467843_-|urease-subunit-gamma
MLLTPREKDKLLVAMAAQVARNRLARGVKLNFPEAVALITDVVVEGARDGRTVAELMQAGAQVLDASQVMEGVPEMIHDIQVEATFPDGTKLVTVHHPIRGAPSPEVPGAVTTPPGEIVFNAGAPRTVVEVANTGDRPIQVGSHYHFFEVNPALRFDRDKARGQRLDIAPGTAVRFEPGATREVALVPLGGARAVYGFRGDVMGSL
>NC_010511.1|WP_012332082.1|2466065_2467199_+|hypothetical-protein
MRFATIRTLDDVLPHVSFERGFVVARGRDCTVVDHVRPVPETFGSPVSLECRGLKFDRDGQIIARPFHKFFELGERQRLEEVDWSAPHAVLDKLDGVMVHPVLLDGRMVFMTRAGATAPARAAQAEANAAILDLSRFLVEGGITPLFEFTSPEAPAILACERPLLTLLAAREMVSGAYLTQPDLAGFGIRFGVRVVAARGMVDDPRAFVARARREEGIEGYVVAFDDGHRVKVKTEAYRLRLRAITGLQRERTVLAWVATGAVDEVAALLPAEAAARLRDHAAAWCAGLATQARAIRAFVAEHAGLPVEEAAARARARFDPRLHRAVRSALGGREPGSALRETLLRAAASDAQADSLRGLFGPSWSPRGLALPELEP
>NC_010511.1|WP_012332081.1|2464212_2465940_-|urease-subunit-alpha
MSNTPKPASLSRAAYAGMFGPTKGDRIRLADTCLIIEVEHDHTRYGEEVKFGGGKVIRDGMGQAQASNQAGAVDTVITNAVVLDHWGIVKCDVGLKGGRIAALGKAGNPDIQDGVTIVVGPGTEVIAGEGKILTAGGFDSHIHYICPQQIEEALNSGVTTMLGGGTGPAHGTFATTCTPGPWHIARMIEAADAFPMNLAFAGKGNASRPESLEEMIRAGACALKLHEDWGTTPAAIDCCLTVADAHDVQVMIHTDTLNESGFVEDTIAAFKGRTIHAFHTEGAGGGHAPDIIKVAGLPNVLPSSTNPTRPYTRNTIDEHLDMLMVCHHLSPSIPEDLAFAESRIRKETIAAEDILHDLGALSIMSSDSQAMGRVGEVVIRTWQTADKMKRQRGALPGEAGDNDNLRARRYVAKYTINPAIAHGVSRHVGSIEPGKLADLVLWSPAFFGVKPDLVIKGGAIATAPMGDPNASIPTPQPVHYRPMFGSFGRVPAATSLTFVSRAAVEDGLAEALRVRKPLVAVENVRGGIGKRSMILNDATPVIEVDPETYDVRADGQLLVCEPADIVPMAQRYFLF
>NC_010511.1|WP_012332080.1|2462284_2463877_-|ABC-transporter-substrate-binding-protein
MRAGLTRRMAVAAAAALALTGGPAAAQGGAAQGGKVLKVVMHSGLRITDPIITTAYIARNHGYMIYDTLFATDERFEIKPQMVKDYAVSDDKLTYTFTLRDGLKFHDGAPVTAEDCIASIQRWGKRDGMGQKLMEYTAALKAVDDRTFTLTLKQPYGLVLASLGKPSSNVPFIMPRRIAETPADRNVPEEIGSGPFRFVKAEFQPGLKAVYEKNPDYVPRAEPPSWLAGGKVVKLDRVEWINIPDYQTAVNALINGEIDYIEQPPHDFLPILKDAKGVVINNYNPLGFSGMVRMNWLNPPFDNPKIRQAVMLALTQQDYLDAQIGNPDYMQLCMALFVCGTPNATEAGAPKTDLARAKQLLKEGGYDGRPVVIMQPTDLAIVAPLGPVTAQALRAIGMKVDLQSMDWQTLVGRRAKQDPVDQGGWNIFHTTWVNADMLNPIANVGVNGKGRTGGWFGWAEDKEIEAMRDAYARETDPAKQKQIAADVQKRAFEVGMYYPTGQYTAPLAVRASLKGILQGPAPVFWNIEKP
>NC_010511.1|WP_012332079.1|2461332_2462274_-|ABC-transporter-permease
MSRFIAGRLAATLPVMGVVAVVVFALLRLAPGDPAAILAGDAASPEQIAAIRARLGLDAPVLQQFGTWLWRLLHGDLGTSIISNQPVTRLIGERIEPTLALATSTILFAVIVAVPLGVVAAWRHGTWIDRGVMAFSVLGFSVPVFVLGYLWIFGAAMKLGLLPVQGYVGPSQGIGPFLERLILPTLTLSVIYVALIARTTRASVLEVLGEDYIRTARAKGVSERRVLGRHALRNAAVPVISVIGLGIALLISGVVVTESVFNLPGLGRLTVDAVLSRDYPVIQGLILFFSGLYVLINLAIDVAYLLVDPRIRY
>NC_010511.1|WP_012332078.1|2460469_2461336_-|ABC-transporter-permease
MSAAAAPRPRALPPALRHPGVLFGLAVLALVLAAALAAPWLGTLDPIQLRPRMRLRPPSGAAWFGTDAFGRDVYSRVVYGARVSLAIGAAVAAIAVAAGLAIGLVAGFVRWLDAIVMRVMDGVMAIPSILLAIALVTLSGAGIGTVIGAIAIPEIPRVARLVRGVVLSVREEPYVEAAIGAGTRLVPLLWRHVLPNTIAPLIVQGTYVCASAVLTEAILSFLGAGIPTEVPSWGNVMAEGRQSFQLAPWVILFPGLCVAATVLAVNILGDGLRDALDPRLARRVGSLR
>NC_010511.1|WP_012332077.1|2458823_2460473_-|ABC-transporter-ATP-binding-protein
MTAPVLEIRDLTIPLPRLSDRAHAVEALSLAVAPGEILCVVGESGSGKSVTAHAVMGLLPPILRPSRGAILLQGEDVLRATPTRLRALRGGRMAMVFQEPMTALNPVLTVGAQIDEILEAHAGRLSAAERRARVLALMGDVHLPDPARMAGAYPHQLSGGQRQRAMIAMALANDPALLIADEPTTALDVTTQAQILRLLRELQARRGTGILFITHDFGVVAEIADRVAVMRGGRLVETGPARAVLRRPQDPYTRMLIAAVPSAVPPPPRRRPPATDPVLAVRRLEKTYGGGLLGRAGRHVRALDGVGLALQPGETLGIVGESGSGKSTLARCIARFVDPSGGEIRLDGTDIARLSGRALHPYRRRVQVIFQDPYRSLNPRRTVGQSITEGPRNYGLPREEALARARRLVGLVGLDAGALDRFPHEFSGGQRQRIAIARALAMEPDLLIADEAVSALDVSVQAQVLDLLEAVRERLGLAILFITHDLRVAARLCDRLIVMRDGQVVEEGETAALFAAPRHAYTRALFAAAPGGAALAAGEASRNTPTGRR
>NC_010511.1|WP_012332076.1|2456049_2458338_-|GAF-domain-containing-protein
MSSAARLPETVELTACDREPIHILGTIQPHGFLLAVQGPDLRIVQISDNVPDRSGRPVAALLGQPLREAFPELRDAVASGMAEHAEREGARYLRTLTLANRAGPTAYDLALHRSEGLIVLELEESSEAAGTDASLDALHPRLNAFVEGLHGAGSVPELCALLARDIRHITGFDRALVYRFDRDWNGTVVAEDGNGVLPSYLDLRFPASDIPAQARELYRRNRLRIIPDAAYAPVPIRPTLTPSSGRPLDLSQSILRSVSPVHVEYMRNMGTMASMSVSILVDGALWGLISCHNKIPRRVPLQARNACDFLTRIFALQLASKERGALAEQRLRLGGIAARLLGHMAEEESFLDGLLRHPEDVLALADAAGAAIVTGEQCRLLGETPGEDAVRGLYAWLAHAHPDEDVVVTDALGEALPEARIHAARASGLLAISISKRYASYVLWFRPEVVRTVRWGGNPAKPATRNEADGSVRLHPRRSFEIWKETVQGRSLPWSEAEIDAAKDLRAAVLGIVLRRAEELAAMTDELTRSNKELEAFSYSVSHDLRAPFRHIVGYSELLRSREGDRLTEKGRHYVDTIIEAAFSAGTLVDNLLTFSQMGRNALNRVSGDMNLLVEEVRRKVMRDVPPERSIRWQVGSLGRVYADPLMLRLVVENLLSNAVKYTRGRDEAVIEVGRGPDAEGEAIFFVRDNGVGFDMAYVNKLFGVFQRLHRVEEFEGTGIGLANVRRIVERHGGRTWAEGSLGAGATFHFTLPTRPEARHRG
>NC_010511.1|WP_012332086.1|2469558_2470860_-|insulinase-family-protein
MTLAADAPSRSASLATATSPAQGRSVIAASGVEAWHVESPVVPLIALAFTFEGGAAQDPEGKSGVVQMLSRLLDEGAGPYGSDAFQERLAARAIELSFHAGPDAIGGSLKMLVKHADEAIELLALALAEPRFDEAAIERVRAQMLAGIRYQQNDPGVMASRRFFAEAYPNHPYGRPSGGTLESVASITRDDLLAMHARLISRARVKVAAVGAIGEAALQRALDAAFGRLSDGGPLAPVPPTRITGLGRRVVVDLDVPQSVIRFGTDGVPWRDPDFIPAYVLNHILGGGAFTSRLFQEVREKRGLAYSVGTSLVSHRAASITWGSTATKNERVGEALSVIGEEIARLTRDGPSDDELQKAKDYLTGSYALGFDTSTKIAHQLVQVAFEGLGIDYIGRRNGLIAAVTQEDIRRAARRTLGDGKLLVVAAGRPGEI
>NC_010511.1|WP_012332087.1|2470918_2472283_-|insulinase-family-protein
MHSRTRPLHRPMSFPGPALRLDAGASGRAEAGGPEVASFVLDNGLDVVVIPDHRAPVATHMIWYRNGSADDPLGQSGIAHFLEHLMFKGTEKNPVGAFSKAVSSLGGQENAFTSFDYTSYFQRVARDNLRTMMEFEADRMTGLVLDDSVVAPERDVVLEERRMRVETDPSAQLSEAMAASLFVHHPYGIPIIGWMHEIEELDRAHALAYYRRFYTPENAILVVAGDVTADEVRRLAEATYGQVAPRGERPVRLRPREPEPRAARRLSVADPKVEQPTLQRLYLAPSCITAREGEGHALELLAEVMGGGPTSYLYRALVMEQGVAVNAGAWYMGSAMDDTRFSVYAVPAEGVSLEKLEEALDATLRNLPAEALAPEAVERGKTRLIAETVYSSDSQSSLARIFGSALAIGESIEEVRRWPTDIEAVGADRLAAAAERYLVPARSVTGYLTKAREG
>NC_010511.1|WP_012332088.1|2472513_2473194_-|hypothetical-protein
MVDQRKILTLAAILCGVAPLCGAAPAARAEDGVFMKKALSSIGLIEPERPPITYRERAPLVLPPKMDKAALPPPAERSAVREAAPQWPTDPESVARARRAAEDAKPRGMRGEQGRMSDNNTTLSIQEMRAGRREGAGIQKEPVYKPGDNVREATWLSPFELFKGKKDESAEPSPVEPSRDMLTDPPTGYRAPPNGRLVRSDSAPKGMPISDREEADPRAYLRSRQQ
>NC_010511.1|WP_012332089.1|2473340_2473838_-|signal-peptidase-II
MRPLILGLATAAATLVLDQATKLGLLLLADLPARQPVVLAPFAQLVVVWNRGVSYGLFQQHTELGRWLLVGVAVLAAAALGAWMARAGSRLLVLSLGLIVGGAVGNAVDRVAYGAVFDFVHLHAGGWSWYVFNVADAGIVAGVAGLLVETVWSEARGDAAMRPDG
>NC_010511.1|WP_012332090.1|2474140_2477110_-|isoleucine--tRNA-ligase
MTETKPVSGRDYSETLFLPQTEFPMRAGLPEREPEILRRWQAIDLYGRIRAAAAGRPKFVLHDGPPYANGHIHIGTALNKILKDLVVRAAGALGHDANYVPGWDCHGLPIEWKIEEQYRAKGRNKDEVPVVEFRRECRAFAEHWLSVQREEFKRLGVTGDWDHPYSTMAFAAEAQIARELMTFAMTGQLYRGSKPVMWSVVEKTALAEAEVEYEDHVSDTIWAAFPVVTSADPALAAAHVVIWTTTPWTIPANRAVAYSRKVEYGLYRVTAAPEENWVQPDFRCIVADKLSGDVFKAARVDAYERLADVAPEALAGLTLAHPLAGWNAGYGFPVPTLEGEHVTDEAGTGFVHTAPSHGREDFEVWMANGRALRERGIDVRIPYTVDADGVLTEEAPGLAGTRVLTEKGEKGDANRAVIAALSAAGTAVARGTLKHSYPHSWRSKKPVIFRNTPQWFIALDAPVAALRERTLREVALAEIAATEWVPPQGQNRITGMIANRPDWVVSRQRAWGVPITVFVRRGTSEILRDPRVNARIAEAFAAEGADAWFADPDGARFLAPDHDPADYEKVTDVLDVWFDSGSTHAFTLEDPVAFPGLAGIRRRRDGGDDTVMYLEGSDQHRGWFHSSLLESCGTRGRAPYDVVLTHGFVLDPKGEKMSKSRGNVVAPQDVIAASGADILRLWVAASDYTDDLRIGPPIIKTFSETYRKLRNSLRWMLGTLAHHRPEDRVAPAEMPELERFILHRLAELDGEIREAYAAYDFKRVVALLNGFMTGDLSSFYFDVRKDALYCDPLSSLVRKASLTVVDEAFRRVVIWLAPVLAFTAEEAWLARTPSQDGSVHLQTLPETPQAWRDEALAARWAKIRRVRRVVTGALEIERAKKRIGASLEAAPVVHVADAELRAALDGIDFAEICITSGIRVVAGEGPAEAFRLDEVRGVSVEPALAEGRKCARSWKVLPSVGSDPEYPDVTPRDAQALREWDALHARAAE
>NC_010511.1|WP_012332091.1|2477427_2477682_+|hypothetical-protein
MVRAALILLALAAGPVLPAAAAASFERAMPARPEIGTPSDEIDATGSLGPTDPFLVPDYDGPEIDVDRPRRDPAERAIREFIPE
>NC_010511.1|WP_012332092.1|2477668_2478634_-|bifunctional-riboflavin-kinase/FAD-synthetase
MIVNRDGEPVPAALRGAVAAIGNFDGLHRGHLALVAAVREMAADRGGPSAVLTFEPHPRDFFAPDRPVFRLTGEGAKLAILARLGLDGVFLRRFDSALAGTSAAGFVTGLLKRDLGLAGVVIGHDFHFGRGREGTPGLLRALCAENGLACRVIDPVAAGGGEAPVSSSAIRAALAAGDIALANHLLGFRWFVEGEVRHGDKRGRVLGFPTANLALPACGLAHGIYAVRARLPDGTMRDGAASYGRRPTFDNGAPLLETTLFDFSGDLYGRRLAVEFVAYLRGEARFDSAEALVAQMHRDAAEARLVLARDTCPSMLGPIRG
>NC_010511.1|WP_012332093.1|2479122_2479506_+|response-regulator
MALDLSMPILVVDDYQTMVRIIRNLLKQLGFEDVDDASDGTGALAKLKQKKYGLVISDWNMEPMTGYELLRHVRADDALRTTPFIMVTAESKTENVIAAKKAGVNNYIVKPFNAQTLKTKIEAVCGA
>NC_010511.1|WP_083784800.1|2479670_2480231_+|chemotaxis-protein
MLMRQKSRKTASRGEADPPAGVDPSTIVRDLVEIAEYIKRLKQAIAHLRANELRRDRLPMAHDELGSVVTATASATNRIMEVAEGILAIEDDTLEGYRAKVEAEVFQIFEACSFQDITGQRIAKVVDALGQVEKRLNHFATVVKVGDGEVDQDEAQRQARRETLLLNGPQLKGPETPQDAIDALFA
>NC_010511.1|WP_012332095.1|2480231_2481137_-|TIGR01459-family-HAD-type-hydrolase
MATRTPRPAPREVPVIDGIAELASGFDVILCDVWGVLHDGLRAHRSASEALSRFRALPGERPRRVVLVSNAPRPGEAVRAQLDGFGVPREAYDGIVTSGDLTRALIEARPGAPLYHLGPERDLPIFEGLSVRRAPPEEAAQVVCTGLFDDEVETAEDYRPVLAGLSARGLPMICANPDLVVERGARLIPCAGALAGLYEALGGEVIYAGKPHRPVYEAALAKAAAVDGAAPAAPERVLAVGDAIRTDIAGASGFGIASVLVARGIHAEELGCHAGEPVGEIAHWLEGQPVHPDAVIDLLRW

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Crispr_ID: NC_010511_13

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_010511_13

2474014-2474099

Orphan

Consensus_repeat	Method
GGGCTTCGCTCAAGCGCCGCGCGG	CRISPRCasFinder

1 spacers

The CRISPR arrays of NC_010511_13

>merge|NC_010511|13|2474014-2474099|CRISPRCasFinder
GGGCTTCGCTCAAGCGCCGCGCGGGCTCCTGATCCGCTTGATCCCTTCGGGACGGCGGGTTCGGGCTTCGCTCAAGCGCCGCGCGG

>NC_010511|13|13|2474014-2474099|CRISPRCasFinder
GGGCTTCGCTCAAGCGCCGCGCGG	GCTCCTGATCCGCTTGATCCCTTCGGGACGGCGGGTTC
GGGCTTCGCTCAAGCGCCGCGCGG

Protein	Signature genes	Signature genes Name	Protein_function
NC_010511.1\|WP_012332084.1\|2467919_2468768_-\|urease-accessory-protein-UreD	unknown	unknown	gnl\|CDD\|223899
NC_010511.1\|WP_012332089.1\|2473340_2473838_-\|signal-peptidase-II	unknown	unknown	gnl\|CDD\|184824
NC_010511.1\|WP_012332081.1\|2464212_2465940_-\|urease-subunit-alpha	unknown	unknown	gnl\|CDD\|237305
NC_010511.1\|WP_083784800.1\|2479670_2480231_+\|chemotaxis-protein	unknown	unknown	gnl\|CDD\|377318
NC_010511.1\|WP_012332091.1\|2477427_2477682_+\|hypothetical-protein	unknown	unknown	unknown
NC_010511.1\|WP_012332092.1\|2477668_2478634_-\|bifunctional-riboflavin-kinase/FAD-synthetase	unknown	unknown	gnl\|CDD\|235536
NC_010511.1\|WP_012332083.1\|2467222_2467843_-\|urease-subunit-gamma	unknown	unknown	gnl\|CDD\|183886
NC_010511.1\|WP_012332088.1\|2472513_2473194_-\|hypothetical-protein	unknown	unknown	unknown
NC_010511.1\|WP_012332099.1\|2485212_2485764_-\|3-hydroxyacyl-[acyl-carrier-protein]-dehydratase-FabA	unknown	unknown	gnl\|CDD\|179953
NC_010511.1\|WP_012332096.1\|2481221_2482916_-\|adenine-deaminase	unknown	unknown	gnl\|CDD\|223933
NC_010511.1\|WP_012332086.1\|2469558_2470860_-\|insulinase-family-protein	unknown	unknown	gnl\|CDD\|223685
NC_010511.1\|WP_012332098.1\|2483888_2485115_-\|beta-ketoacyl-ACP-synthase-I	unknown	unknown	gnl\|CDD\|181184
NC_010511.1\|WP_012332093.1\|2479122_2479506_+\|response-regulator	unknown	unknown	gnl\|CDD\|381150
NC_010511.1\|WP_012332097.1\|2483025_2483853_-\|enoyl-ACP-reductase-FabI	unknown	unknown	gnl\|CDD\|180596
NC_010511.1\|WP_012332080.1\|2462284_2463877_-\|ABC-transporter-substrate-binding-protein	unknown	unknown	gnl\|CDD\|173867
NC_010511.1\|WP_012332085.1\|2468923_2469361_+\|cupin-domain-containing-protein	unknown	unknown	gnl\|CDD\|226586
NC_010511.1\|WP_012332095.1\|2480231_2481137_-\|TIGR01459-family-HAD-type-hydrolase	unknown	unknown	gnl\|CDD\|319827
NC_010511.1\|WP_012332087.1\|2470918_2472283_-\|insulinase-family-protein	unknown	unknown	gnl\|CDD\|223685
NC_010511.1\|WP_012332082.1\|2466065_2467199_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|213699
NC_010511.1\|WP_012332090.1\|2474140_2477110_-\|isoleucine--tRNA-ligase	unknown	unknown	gnl\|CDD\|237514

Protein	Function_ID	Function_description	E-value
NC_010511.1\|WP_012332084.1\|2467919_2468768_-\|urease-accessory-protein-UreD	gnl\|CDD\|223899	COG0829, UreH, Urease accessory protein UreH [Posttranslational modification, protein turnover, chaperones].	1.24216e-62
NC_010511.1\|WP_012332089.1\|2473340_2473838_-\|signal-peptidase-II	gnl\|CDD\|184824	PRK14796, PRK14796, lipoprotein signal peptidase; Provisional.	7.93796e-73
NC_010511.1\|WP_012332081.1\|2464212_2465940_-\|urease-subunit-alpha	gnl\|CDD\|237305	PRK13207, ureC, urease subunit alpha; Reviewed.	0
NC_010511.1\|WP_083784800.1\|2479670_2480231_+\|chemotaxis-protein	gnl\|CDD\|377318	pfam04344, CheZ, Chemotaxis phosphatase, CheZ. This family represents the bacterial chemotaxis phosphatase, CheZ. This protein forms a dimer characterized by a long four-helix bundle, composed of two helices from each monomer. CheZ dephosphorylates CheY in a reaction that is essential to maintain a continuous chemotactic response to environmental changes. It is thought that CheZ's conserved residue Gln 147 orientates a water molecule for nucleophilic attack at the CheY active site.	7.73731e-05
NC_010511.1\|WP_012332096.1\|2481221_2482916_-\|adenine-deaminase	gnl\|CDD\|223933	COG1001, AdeC, Adenine deaminase [Nucleotide transport and metabolism].	0
NC_010511.1\|WP_012332092.1\|2477668_2478634_-\|bifunctional-riboflavin-kinase/FAD-synthetase	gnl\|CDD\|235536	PRK05627, PRK05627, bifunctional riboflavin kinase/FAD synthetase.	1.02149e-121
NC_010511.1\|WP_012332083.1\|2467222_2467843_-\|urease-subunit-gamma	gnl\|CDD\|183886	PRK13192, PRK13192, bifunctional urease subunit gamma/beta; Reviewed.	3.67952e-103
NC_010511.1\|WP_012332099.1\|2485212_2485764_-\|3-hydroxyacyl-[acyl-carrier-protein]-dehydratase-FabA	gnl\|CDD\|179953	PRK05174, PRK05174, bifunctional 3-hydroxydecanoyl-ACP dehydratase/trans-2-decenoyl-ACP isomerase.	1.73365e-122
NC_010511.1\|WP_012332086.1\|2469558_2470860_-\|insulinase-family-protein	gnl\|CDD\|223685	COG0612, PqqL, Predicted Zn-dependent peptidases [General function prediction only].	1.59261e-81
NC_010511.1\|WP_012332098.1\|2483888_2485115_-\|beta-ketoacyl-ACP-synthase-I	gnl\|CDD\|181184	PRK07967, PRK07967, beta-ketoacyl-ACP synthase I.	0
NC_010511.1\|WP_012332093.1\|2479122_2479506_+\|response-regulator	gnl\|CDD\|381150	cd19923, REC_CheY_CheY3, phosphoacceptor receiver (REC) domain of chemotaxis response regulator CheY3 and similar CheY family proteins. CheY family chemotaxis response regulators (RRs) comprise about 17% of bacterial RRs and almost half of all RRs in archaea. This subfamily contains Vibrio cholerae CheY3, Escherichia coli CheY, and similar CheY family RRs. CheY proteins control bacterial motility and participate in signaling phosphorelays and in protein-protein interactions. CheY RRs contain only the REC domain with no output/effector domain. REC domains function as phosphorylation-mediated switches within response regulators, but some also transfer phosphoryl groups in multistep phosphorelays.	1.47309e-59
NC_010511.1\|WP_012332097.1\|2483025_2483853_-\|enoyl-ACP-reductase-FabI	gnl\|CDD\|180596	PRK06505, PRK06505, enoyl-[acyl-carrier-protein] reductase FabI.	8.81814e-176
NC_010511.1\|WP_012332080.1\|2462284_2463877_-\|ABC-transporter-substrate-binding-protein	gnl\|CDD\|173867	cd08502, PBP2_NikA_DppA_OppA_like_16, The substrate-binding component of an uncharacterized ABC-type nickel/dipeptide/oligopeptide-like import system contains the type 2 periplasmic binding fold. This CD represents the substrate-binding domain of an uncharacterized ATP-binding cassette (ABC) type nickel/dipeptide/oligopeptide-like transporter. The oligopeptide-binding protein OppA and the dipeptide-binding protein DppA show significant sequence similarity to NikA, the initial nickel receptor. The DppA binds dipeptides and some tripeptides and is involved in chemotaxis toward dipeptides, whereas the OppA binds peptides of a wide range of lengths (2-35 amino acid residues) and plays a role in recycling of cell wall peptides, which precludes any involvement in chemotaxis. Most of other periplasmic binding proteins are comprised of only two globular subdomains corresponding to domains I and III of the dipeptide/oligopeptide binding proteins. The structural topology of these domains is most similar to that of the type 2 periplasmic binding proteins (PBP2), which are responsible for the uptake of a variety of substrates such as phosphate, sulfate, polysaccharides, lysine/arginine/ornithine, and histidine. The PBP2 bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap. After binding their specific ligand with high affinity, they can interact with a cognate membrane transport complex comprised of two integral membrane domains and two cytoplasmically located ATPase domains. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis. Besides transport proteins, the PBP2 superfamily includes the ligand-binding domains from ionotropic glutamate receptors, LysR-type transcriptional regulators, and unorthodox sensor proteins involved in signal transduction.	0
NC_010511.1\|WP_012332085.1\|2468923_2469361_+\|cupin-domain-containing-protein	gnl\|CDD\|226586	COG4101, COG4101, Predicted mannose-6-phosphate isomerase [Carbohydrate transport and metabolism].	3.02056e-55
NC_010511.1\|WP_012332095.1\|2480231_2481137_-\|TIGR01459-family-HAD-type-hydrolase	gnl\|CDD\|319827	cd07525, HAD_like, uncharacterized family of the haloacid dehalogenase-like (HAD) hydrolase superfamily. The haloacid dehalogenase-like (HAD) hydrolases are a large superfamily of diverse enzymes that catalyze carbon or phosphoryl group transfer reactions on a range of substrates, using an active site aspartate in nucleophilic catalysis. Members include 2-L-haloalkanoic acid dehalogenase (C-Cl bond hydrolysis), azetidine hydrolase (C-N bond hydrolysis); phosphonoacetaldehyde hydrolase (C-P bond hydrolysis), phosphoserine phosphatase and phosphomannomutase (CO-P bond hydrolysis), P-type ATPases (PO-P bond hydrolysis) and many others. Members are found in all three kingdoms of life, and most genomes are predicted to contain multiple HAD-like proteins. Members possess a highly conserved alpha/beta core domain, and many also possess a small cap domain, the fold and function of which is variable. HAD hydrolases are sometimes referred to as belonging to the DDDD superfamily of phosphohydrolases.	1.09524e-87
NC_010511.1\|WP_012332087.1\|2470918_2472283_-\|insulinase-family-protein	gnl\|CDD\|223685	COG0612, PqqL, Predicted Zn-dependent peptidases [General function prediction only].	8.48854e-95
NC_010511.1\|WP_012332082.1\|2466065_2467199_+\|hypothetical-protein	gnl\|CDD\|213699	TIGR02308, T4_RNA_ligase_1, RNA ligase, T4 RnlA family. Members of this family are phage proteins with ATP-dependent RNA ligase activity. Host defense to phage may include cleavage and inactivation of specific tRNA molecules; members of this family act to reverse this RNA damage. The enzyme is adenylated, transiently, on a Lys residue in a motif KXDGSL. [Mobile and extrachromosomal element functions, Prophage functions, Transcription, RNA processing].	9.27143e-27
NC_010511.1\|WP_012332090.1\|2474140_2477110_-\|isoleucine--tRNA-ligase	gnl\|CDD\|237514	PRK13804, ileS, isoleucyl-tRNA synthetase; Provisional.	0

>NC_010511.1|WP_012332089.1|2473340_2473838_-|signal-peptidase-II
MRPLILGLATAAATLVLDQATKLGLLLLADLPARQPVVLAPFAQLVVVWNRGVSYGLFQQHTELGRWLLVGVAVLAAAALGAWMARAGSRLLVLSLGLIVGGAVGNAVDRVAYGAVFDFVHLHAGGWSWYVFNVADAGIVAGVAGLLVETVWSEARGDAAMRPDG
>NC_010511.1|WP_012332088.1|2472513_2473194_-|hypothetical-protein
MVDQRKILTLAAILCGVAPLCGAAPAARAEDGVFMKKALSSIGLIEPERPPITYRERAPLVLPPKMDKAALPPPAERSAVREAAPQWPTDPESVARARRAAEDAKPRGMRGEQGRMSDNNTTLSIQEMRAGRREGAGIQKEPVYKPGDNVREATWLSPFELFKGKKDESAEPSPVEPSRDMLTDPPTGYRAPPNGRLVRSDSAPKGMPISDREEADPRAYLRSRQQ
>NC_010511.1|WP_012332087.1|2470918_2472283_-|insulinase-family-protein
MHSRTRPLHRPMSFPGPALRLDAGASGRAEAGGPEVASFVLDNGLDVVVIPDHRAPVATHMIWYRNGSADDPLGQSGIAHFLEHLMFKGTEKNPVGAFSKAVSSLGGQENAFTSFDYTSYFQRVARDNLRTMMEFEADRMTGLVLDDSVVAPERDVVLEERRMRVETDPSAQLSEAMAASLFVHHPYGIPIIGWMHEIEELDRAHALAYYRRFYTPENAILVVAGDVTADEVRRLAEATYGQVAPRGERPVRLRPREPEPRAARRLSVADPKVEQPTLQRLYLAPSCITAREGEGHALELLAEVMGGGPTSYLYRALVMEQGVAVNAGAWYMGSAMDDTRFSVYAVPAEGVSLEKLEEALDATLRNLPAEALAPEAVERGKTRLIAETVYSSDSQSSLARIFGSALAIGESIEEVRRWPTDIEAVGADRLAAAAERYLVPARSVTGYLTKAREG
>NC_010511.1|WP_012332086.1|2469558_2470860_-|insulinase-family-protein
MTLAADAPSRSASLATATSPAQGRSVIAASGVEAWHVESPVVPLIALAFTFEGGAAQDPEGKSGVVQMLSRLLDEGAGPYGSDAFQERLAARAIELSFHAGPDAIGGSLKMLVKHADEAIELLALALAEPRFDEAAIERVRAQMLAGIRYQQNDPGVMASRRFFAEAYPNHPYGRPSGGTLESVASITRDDLLAMHARLISRARVKVAAVGAIGEAALQRALDAAFGRLSDGGPLAPVPPTRITGLGRRVVVDLDVPQSVIRFGTDGVPWRDPDFIPAYVLNHILGGGAFTSRLFQEVREKRGLAYSVGTSLVSHRAASITWGSTATKNERVGEALSVIGEEIARLTRDGPSDDELQKAKDYLTGSYALGFDTSTKIAHQLVQVAFEGLGIDYIGRRNGLIAAVTQEDIRRAARRTLGDGKLLVVAAGRPGEI
>NC_010511.1|WP_012332085.1|2468923_2469361_+|cupin-domain-containing-protein
MSDLTDSSTCRVVGAGDAFVGKQALTYRPGISAESVGARGIHLQSVNMPPGARAKAHLHEGHETALHVLSGVAGMWYGPRLEHHMWNRAGDYVYIPAGMPHLPYNASRTETVVAVIARTDPNEQESVVLRPDLDALRPAGEDPMA
>NC_010511.1|WP_012332084.1|2467919_2468768_-|urease-accessory-protein-UreD
MSSHPTPSWPRRQRSEGRVALGAGLVAGGTTRLTDLAETGPLRLRLPRVEGAALEGVLLNSAGGLACGDRFAVAAEIGEGADMVLTTTAAEKIYRSDGPVTEIAAELRLGPRARLAWLPQETILYDGARLSRRLTAEIAPDAALTLFEALVFGRSARGETVREGEIRDAWRLARGGRLVYADTLRLDGAVAAHLARPAIAGGARAVATLVHAAPDAESRLDGLRGLIAAAGCAALGVEAGASAWNGLLVLRLLAPESAPLRRAATRILEGFRGLPLPRVWQT
>NC_010511.1|WP_012332083.1|2467222_2467843_-|urease-subunit-gamma
MLLTPREKDKLLVAMAAQVARNRLARGVKLNFPEAVALITDVVVEGARDGRTVAELMQAGAQVLDASQVMEGVPEMIHDIQVEATFPDGTKLVTVHHPIRGAPSPEVPGAVTTPPGEIVFNAGAPRTVVEVANTGDRPIQVGSHYHFFEVNPALRFDRDKARGQRLDIAPGTAVRFEPGATREVALVPLGGARAVYGFRGDVMGSL
>NC_010511.1|WP_012332082.1|2466065_2467199_+|hypothetical-protein
MRFATIRTLDDVLPHVSFERGFVVARGRDCTVVDHVRPVPETFGSPVSLECRGLKFDRDGQIIARPFHKFFELGERQRLEEVDWSAPHAVLDKLDGVMVHPVLLDGRMVFMTRAGATAPARAAQAEANAAILDLSRFLVEGGITPLFEFTSPEAPAILACERPLLTLLAAREMVSGAYLTQPDLAGFGIRFGVRVVAARGMVDDPRAFVARARREEGIEGYVVAFDDGHRVKVKTEAYRLRLRAITGLQRERTVLAWVATGAVDEVAALLPAEAAARLRDHAAAWCAGLATQARAIRAFVAEHAGLPVEEAAARARARFDPRLHRAVRSALGGREPGSALRETLLRAAASDAQADSLRGLFGPSWSPRGLALPELEP
>NC_010511.1|WP_012332081.1|2464212_2465940_-|urease-subunit-alpha
MSNTPKPASLSRAAYAGMFGPTKGDRIRLADTCLIIEVEHDHTRYGEEVKFGGGKVIRDGMGQAQASNQAGAVDTVITNAVVLDHWGIVKCDVGLKGGRIAALGKAGNPDIQDGVTIVVGPGTEVIAGEGKILTAGGFDSHIHYICPQQIEEALNSGVTTMLGGGTGPAHGTFATTCTPGPWHIARMIEAADAFPMNLAFAGKGNASRPESLEEMIRAGACALKLHEDWGTTPAAIDCCLTVADAHDVQVMIHTDTLNESGFVEDTIAAFKGRTIHAFHTEGAGGGHAPDIIKVAGLPNVLPSSTNPTRPYTRNTIDEHLDMLMVCHHLSPSIPEDLAFAESRIRKETIAAEDILHDLGALSIMSSDSQAMGRVGEVVIRTWQTADKMKRQRGALPGEAGDNDNLRARRYVAKYTINPAIAHGVSRHVGSIEPGKLADLVLWSPAFFGVKPDLVIKGGAIATAPMGDPNASIPTPQPVHYRPMFGSFGRVPAATSLTFVSRAAVEDGLAEALRVRKPLVAVENVRGGIGKRSMILNDATPVIEVDPETYDVRADGQLLVCEPADIVPMAQRYFLF
>NC_010511.1|WP_012332080.1|2462284_2463877_-|ABC-transporter-substrate-binding-protein
MRAGLTRRMAVAAAAALALTGGPAAAQGGAAQGGKVLKVVMHSGLRITDPIITTAYIARNHGYMIYDTLFATDERFEIKPQMVKDYAVSDDKLTYTFTLRDGLKFHDGAPVTAEDCIASIQRWGKRDGMGQKLMEYTAALKAVDDRTFTLTLKQPYGLVLASLGKPSSNVPFIMPRRIAETPADRNVPEEIGSGPFRFVKAEFQPGLKAVYEKNPDYVPRAEPPSWLAGGKVVKLDRVEWINIPDYQTAVNALINGEIDYIEQPPHDFLPILKDAKGVVINNYNPLGFSGMVRMNWLNPPFDNPKIRQAVMLALTQQDYLDAQIGNPDYMQLCMALFVCGTPNATEAGAPKTDLARAKQLLKEGGYDGRPVVIMQPTDLAIVAPLGPVTAQALRAIGMKVDLQSMDWQTLVGRRAKQDPVDQGGWNIFHTTWVNADMLNPIANVGVNGKGRTGGWFGWAEDKEIEAMRDAYARETDPAKQKQIAADVQKRAFEVGMYYPTGQYTAPLAVRASLKGILQGPAPVFWNIEKP
>NC_010511.1|WP_012332090.1|2474140_2477110_-|isoleucine--tRNA-ligase
MTETKPVSGRDYSETLFLPQTEFPMRAGLPEREPEILRRWQAIDLYGRIRAAAAGRPKFVLHDGPPYANGHIHIGTALNKILKDLVVRAAGALGHDANYVPGWDCHGLPIEWKIEEQYRAKGRNKDEVPVVEFRRECRAFAEHWLSVQREEFKRLGVTGDWDHPYSTMAFAAEAQIARELMTFAMTGQLYRGSKPVMWSVVEKTALAEAEVEYEDHVSDTIWAAFPVVTSADPALAAAHVVIWTTTPWTIPANRAVAYSRKVEYGLYRVTAAPEENWVQPDFRCIVADKLSGDVFKAARVDAYERLADVAPEALAGLTLAHPLAGWNAGYGFPVPTLEGEHVTDEAGTGFVHTAPSHGREDFEVWMANGRALRERGIDVRIPYTVDADGVLTEEAPGLAGTRVLTEKGEKGDANRAVIAALSAAGTAVARGTLKHSYPHSWRSKKPVIFRNTPQWFIALDAPVAALRERTLREVALAEIAATEWVPPQGQNRITGMIANRPDWVVSRQRAWGVPITVFVRRGTSEILRDPRVNARIAEAFAAEGADAWFADPDGARFLAPDHDPADYEKVTDVLDVWFDSGSTHAFTLEDPVAFPGLAGIRRRRDGGDDTVMYLEGSDQHRGWFHSSLLESCGTRGRAPYDVVLTHGFVLDPKGEKMSKSRGNVVAPQDVIAASGADILRLWVAASDYTDDLRIGPPIIKTFSETYRKLRNSLRWMLGTLAHHRPEDRVAPAEMPELERFILHRLAELDGEIREAYAAYDFKRVVALLNGFMTGDLSSFYFDVRKDALYCDPLSSLVRKASLTVVDEAFRRVVIWLAPVLAFTAEEAWLARTPSQDGSVHLQTLPETPQAWRDEALAARWAKIRRVRRVVTGALEIERAKKRIGASLEAAPVVHVADAELRAALDGIDFAEICITSGIRVVAGEGPAEAFRLDEVRGVSVEPALAEGRKCARSWKVLPSVGSDPEYPDVTPRDAQALREWDALHARAAE
>NC_010511.1|WP_012332091.1|2477427_2477682_+|hypothetical-protein
MVRAALILLALAAGPVLPAAAAASFERAMPARPEIGTPSDEIDATGSLGPTDPFLVPDYDGPEIDVDRPRRDPAERAIREFIPE
>NC_010511.1|WP_012332092.1|2477668_2478634_-|bifunctional-riboflavin-kinase/FAD-synthetase
MIVNRDGEPVPAALRGAVAAIGNFDGLHRGHLALVAAVREMAADRGGPSAVLTFEPHPRDFFAPDRPVFRLTGEGAKLAILARLGLDGVFLRRFDSALAGTSAAGFVTGLLKRDLGLAGVVIGHDFHFGRGREGTPGLLRALCAENGLACRVIDPVAAGGGEAPVSSSAIRAALAAGDIALANHLLGFRWFVEGEVRHGDKRGRVLGFPTANLALPACGLAHGIYAVRARLPDGTMRDGAASYGRRPTFDNGAPLLETTLFDFSGDLYGRRLAVEFVAYLRGEARFDSAEALVAQMHRDAAEARLVLARDTCPSMLGPIRG
>NC_010511.1|WP_012332093.1|2479122_2479506_+|response-regulator
MALDLSMPILVVDDYQTMVRIIRNLLKQLGFEDVDDASDGTGALAKLKQKKYGLVISDWNMEPMTGYELLRHVRADDALRTTPFIMVTAESKTENVIAAKKAGVNNYIVKPFNAQTLKTKIEAVCGA
>NC_010511.1|WP_083784800.1|2479670_2480231_+|chemotaxis-protein
MLMRQKSRKTASRGEADPPAGVDPSTIVRDLVEIAEYIKRLKQAIAHLRANELRRDRLPMAHDELGSVVTATASATNRIMEVAEGILAIEDDTLEGYRAKVEAEVFQIFEACSFQDITGQRIAKVVDALGQVEKRLNHFATVVKVGDGEVDQDEAQRQARRETLLLNGPQLKGPETPQDAIDALFA
>NC_010511.1|WP_012332095.1|2480231_2481137_-|TIGR01459-family-HAD-type-hydrolase
MATRTPRPAPREVPVIDGIAELASGFDVILCDVWGVLHDGLRAHRSASEALSRFRALPGERPRRVVLVSNAPRPGEAVRAQLDGFGVPREAYDGIVTSGDLTRALIEARPGAPLYHLGPERDLPIFEGLSVRRAPPEEAAQVVCTGLFDDEVETAEDYRPVLAGLSARGLPMICANPDLVVERGARLIPCAGALAGLYEALGGEVIYAGKPHRPVYEAALAKAAAVDGAAPAAPERVLAVGDAIRTDIAGASGFGIASVLVARGIHAEELGCHAGEPVGEIAHWLEGQPVHPDAVIDLLRW
>NC_010511.1|WP_012332096.1|2481221_2482916_-|adenine-deaminase
MSDEIARRIAQGAGRAPADLVIRDARLLDLVTGDLVDTDIAVCGDGIVGTYGEYAGTRVIEAEGRVAVPGFIDTHLHVESSLITPHEFDRCVLPHGVTTAIWDPHELANVLGTAAFDYALQAARETVMDIRVQLSSCVPATDLESSGARIEAEALRPYRDHPGSLGLAEFMNFPGIVAGDPACLAKLALFAGRHVDGHAPLLSGRDLNAYVAAGIRTDHETTGPAEALEKIRKGMTVLIREGSVSKDLRALAPLLTVATSPFLAFCTDDRNPLDIAEEGHLDALIRMAIGLGVAPLAAYRAASLSAATAFGLADRGMIAPGRRADIVLLDDVETCAVARVIAGGRPAEEALAAPRTRTPAPGRGSVKAAPVAPEAFRVAAAPGETSVIGVVPGRIITEHRRLTLPARDGAALCDLAQDAVKVAVIARHGAPGMACGFVQGFGLRRGAIASSVGHDSHNLCVVGADEADMALAVNRLIALQGGFVVAEGGAVRAELALPIAGLMSDLPFEAVRDALHPLREAARGLGCTLPEPFLQVAFLPLPMIPHLKITDRGLVDVDRMRILP
>NC_010511.1|WP_012332097.1|2483025_2483853_-|enoyl-ACP-reductase-FabI
MTGLMAGKRGLVLGVANDHSIAWGIAKALAAQGAELAFTYQGEALGRRVTPLAHSLGSRIVLPCDVEDPASVAAVFSALDDHWPEGFDFLVHAIGYSDKAQLKGRYVDVTTRENFSRTMVISCFSFTELAQRAAKRLRPGGTLLTLTFGGATRVMPNYNVMGLAKAALEASVRYLAADLGPDGIRVNAISAGPVRTLAGAGIADARLMFNHQRAHSPLRRNATIEEIGGAALYLLSDLSGGVTGEVHFVDSGFNIIAMPRPAVLKAQDDAGVVGD
>NC_010511.1|WP_012332098.1|2483888_2485115_-|beta-ketoacyl-ACP-synthase-I
MRRVAITGMGIVSSIGNTTQEVLASLREARSGITRAEPFAAHGFRCQVQGAPTLDPETVVDRRAMRFHGGGTAWNHVAMEQAIRDAGLEESEVSHERTGIIMGSGGPSTHAIVEAADIARAKGPKRVGPFAVPKAMSSTASATLATWFKIKGVNYSISSACATSNHCIGNAAEIIQAGRQDIIFAGGCEELDWTLSVLFDAMGAMSAKYNDTPARASRAYDAARDGFVIAGGAGVLVLEELEHAKARGARIYGEIAGYGATSDGHDMVAPSGEGAVRCMRQALEGLKGVKIDYINPHATSTPVGDEKEIEAIREVFGSGESCPPIAATKSLTGHSLGATGVQEAIYSLLMMNNGFICESANIEELDPAFADMPILRRRVDDARLGHVLSNSFGFGGTNATLVLKHVDA
>NC_010511.1|WP_012332099.1|2485212_2485764_-|3-hydroxyacyl-[acyl-carrier-protein]-dehydratase-FabA
MAADTPAADAPNRPSQFSYEDLLACGRGEMFGAGNAQLPLPPMLMFDRITSIGQEGGVHGKGHVRAELDVRPDLWFFPCHFHGDPVMPGCLGLDALWQMVGFYLGWLGAPGRGRALGVGEVKLAGQVLPSVKRVVYGVDLKRVRQGRLVLGIADGWLEADGERVYDAKDLRVGLFQAVTPAGG

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Crispr_ID: NC_010511_14

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_010511_14

2625133-2625688

Unclear

Consensus_repeat	Method
ATCGCCCCCTCGCGGGGGCGCGGATTGAAAC	PILER-CR
ATCGCCCCCTCGCGGGGGCGCGGATTGAAAC	CRISPRCasFinder
ATCGCCCCCTCGCGGGGGCGCGGATTGAAAC	CRT

8 spacers

cas2

The CRISPR arrays of NC_010511_14

>merge|NC_010511|14|2625133-2625688|PILER-CR,CRISPRCasFinder,CRT
ATCGCCCCCTCGCGGGGGCGCGGATTGAAACGTGCACGATACGACCGGCATGGGGGCGGGTGACGCATCGCCCCCTCGCGGGGGCGCGGATTGAAACTGTCTCCGTCCGCCTACAACGGGTTGATCACCCGATCGCCCCCTCGCGGGGGCGCGGATTGAAACTTGCTGCGGCCTTGATCGTCATTCGATCCTGGCATCGCCCCCTCGCGGGGGCGCGGATTGAAACGTCACGCATTGGATGCCCGTCCCTGAACCGCCGCCATCGCCCCCTCGCGGGGGCGCGGATTGAAACTGAGCATGACGGCATCGCTTCAGACACCCTCCGAGGATCGCCCCCTCGCGGGGGCGCGGATTGAAACCGCTACGAGGAGCTCAATCAGTTCATTATGGCCGGATCGCCCCCTCGCGGGGGCGCGGATTGAAACAACGCAAGCGCGACGCCGGTTCGACTTCGGCTTTATCGCCCCCTAGCGGGGGCGCGGATTGAAACCAGTCGTACCAGACCTCGGGCGGGCGGCTGCCGAGATCGCCCCCTCGCGGGGGCGCGGATTGATAA

>NC_010511|14|2|2625133-2625622|PILER-CR
ATCGCCCCCTCGCGGGGGCGCGGATTGAAAC	GTGCACGATACGACCGGCATGGGGGCGGGTGACGC
ATCGCCCCCTCGCGGGGGCGCGGATTGAAAC	TGTCTCCGTCCGCCTACAACGGGTTGATCACCCG
ATCGCCCCCTCGCGGGGGCGCGGATTGAAAC	TTGCTGCGGCCTTGATCGTCATTCGATCCTGGC
ATCGCCCCCTCGCGGGGGCGCGGATTGAAAC	GTCACGCATTGGATGCCCGTCCCTGAACCGCCGCC
ATCGCCCCCTCGCGGGGGCGCGGATTGAAAC	TGAGCATGACGGCATCGCTTCAGACACCCTCCGAGG
ATCGCCCCCTCGCGGGGGCGCGGATTGAAAC	CGCTACGAGGAGCTCAATCAGTTCATTATGGCCGG
ATCGCCCCCTCGCGGGGGCGCGGATTGAAAC	AACGCAAGCGCGACGCCGGTTCGACTTCGGCTTT
ATCGCCCCCTAGCGGGGGCGCGGATTGAAAC

>NC_010511|14|14|2625133-2625688|CRISPRCasFinder
ATCGCCCCCTCGCGGGGGCGCGGATTGAAAC	GTGCACGATACGACCGGCATGGGGGCGGGTGACGC
ATCGCCCCCTCGCGGGGGCGCGGATTGAAAC	TGTCTCCGTCCGCCTACAACGGGTTGATCACCCG
ATCGCCCCCTCGCGGGGGCGCGGATTGAAAC	TTGCTGCGGCCTTGATCGTCATTCGATCCTGGC
ATCGCCCCCTCGCGGGGGCGCGGATTGAAAC	GTCACGCATTGGATGCCCGTCCCTGAACCGCCGCC
ATCGCCCCCTCGCGGGGGCGCGGATTGAAAC	TGAGCATGACGGCATCGCTTCAGACACCCTCCGAGG
ATCGCCCCCTCGCGGGGGCGCGGATTGAAAC	CGCTACGAGGAGCTCAATCAGTTCATTATGGCCGG
ATCGCCCCCTCGCGGGGGCGCGGATTGAAAC	AACGCAAGCGCGACGCCGGTTCGACTTCGGCTTT
ATCGCCCCCTAGCGGGGGCGCGGATTGAAAC	CAGTCGTACCAGACCTCGGGCGGGCGGCTGCCGAG
ATCGCCCCCTCGCGGGGGCGCGGATTGATAA

>NC_010511|14|2|2625133-2625688|CRT
ATCGCCCCCTCGCGGGGGCGCGGATTGAAAC	GTGCACGATACGACCGGCATGGGGGCGGGTGACGC
ATCGCCCCCTCGCGGGGGCGCGGATTGAAAC	TGTCTCCGTCCGCCTACAACGGGTTGATCACCCG
ATCGCCCCCTCGCGGGGGCGCGGATTGAAAC	TTGCTGCGGCCTTGATCGTCATTCGATCCTGGC
ATCGCCCCCTCGCGGGGGCGCGGATTGAAAC	GTCACGCATTGGATGCCCGTCCCTGAACCGCCGCC
ATCGCCCCCTCGCGGGGGCGCGGATTGAAAC	TGAGCATGACGGCATCGCTTCAGACACCCTCCGAGG
ATCGCCCCCTCGCGGGGGCGCGGATTGAAAC	CGCTACGAGGAGCTCAATCAGTTCATTATGGCCGG
ATCGCCCCCTCGCGGGGGCGCGGATTGAAAC	AACGCAAGCGCGACGCCGGTTCGACTTCGGCTTT
ATCGCCCCCTAGCGGGGGCGCGGATTGAAAC	CAGTCGTACCAGACCTCGGGCGGGCGGCTGCCGAG
ATCGCCCCCTCGCGGGGGCGCGGATTGATAA

Protein	Signature genes	Signature genes Name	Protein_function
NC_010511.1\|WP_012332215.1\|2612764_2613718_-\|protoheme-IX-farnesyltransferase	unknown	unknown	gnl\|CDD\|235293
NC_010511.1\|WP_012332222.1\|2623348_2624200_+\|formate-dehydrogenase-accessory-sulfurtransferase-FdhD	unknown	unknown	gnl\|CDD\|234823
NC_010511.1\|WP_012332230.1\|2630432_2632520_+\|HAMP-domain-containing-protein	unknown	unknown	gnl\|CDD\|223910
NC_010511.1\|WP_012332227.1\|2627314_2628427_+\|GTP-cyclohydrolase-II-RibA	unknown	unknown	gnl\|CDD\|236340
NC_010511.1\|WP_012332233.1\|2634617_2635079_+\|transcription-elongation-factor-GreA	unknown	unknown	gnl\|CDD\|180535
NC_010511.1\|WP_012332232.1\|2633561_2634548_+\|oxidoreductase	unknown	unknown	gnl\|CDD\|176248
NC_010511.1\|WP_043701109.1\|2626495_2627263_-\|deaminase/reductase	unknown	unknown	gnl\|CDD\|224896
NC_010511.1\|WP_012332225.1\|2625947_2626484_-\|cytochrome-b	unknown	unknown	gnl\|CDD\|225580
NC_010511.1\|WP_012332234.1\|2635062_2635962_-\|LysR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|223656
NC_010511.1\|WP_043702277.1\|2615556_2616420_-\|cytochrome-c-oxidase-subunit-II	unknown	unknown	gnl\|CDD\|224537
NC_010511.1\|WP_012332216.1\|2613840_2615469_-\|cytochrome-c-oxidase-subunit-I	unknown	unknown	gnl\|CDD\|238833
NC_010511.1\|WP_012332220.1\|2618298_2618772_+\|formate-dehydrogenase-subunit-gamma	unknown	unknown	gnl\|CDD\|180339
NC_010511.1\|WP_012332229.1\|2629319_2630093_+\|helix-turn-helix-domain-containing-protein	unknown	unknown	gnl\|CDD\|375319
NC_010511.1\|WP_012332219.1\|2617740_2618139_-\|GFA-family-protein	unknown	unknown	gnl\|CDD\|226314
NC_010511.1\|WP_012332223.1\|2624196_2624439_+\|formate-dehydrogenase-subunit-delta	unknown	unknown	gnl\|CDD\|378656
NC_010511.1\|WP_012332231.1\|2632889_2633441_+\|hypothetical-protein	unknown	unknown	unknown
NC_010511.1\|WP_012332218.1\|2616801_2617710_+\|LysR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|223656
NC_010511.1\|WP_012332228.1\|2628476_2629241_-\|class-I-SAM-dependent-methyltransferase	unknown	unknown	gnl\|CDD\|369777
NC_010511.1\|WP_012332221.1\|2618768_2620328_+\|formate-dehydrogenase-beta-subunit	unknown	unknown	gnl\|CDD\|224806
NC_010511.1\|WP_012332224.1\|2624666_2624951_+\|CRISPR-associated-endonuclease-Cas2	cas2	cd09725_cas2_CAS-I:CAS-II:CAS-III:CAS-V	gnl\|CDD\|187856

Protein	Function_ID	Function_description	E-value
NC_010511.1\|WP_012332215.1\|2612764_2613718_-\|protoheme-IX-farnesyltransferase	gnl\|CDD\|235293	PRK04375, PRK04375, protoheme IX farnesyltransferase; Provisional.	1.33604e-133
NC_010511.1\|WP_012332222.1\|2623348_2624200_+\|formate-dehydrogenase-accessory-sulfurtransferase-FdhD	gnl\|CDD\|234823	PRK00724, PRK00724, formate dehydrogenase accessory sulfurtransferase FdhD.	2.73931e-96
NC_010511.1\|WP_012332230.1\|2630432_2632520_+\|HAMP-domain-containing-protein	gnl\|CDD\|223910	COG0840, Tar, Methyl-accepting chemotaxis protein [Cell motility and secretion / Signal transduction mechanisms].	4.48681e-38
NC_010511.1\|WP_012332227.1\|2627314_2628427_+\|GTP-cyclohydrolase-II-RibA	gnl\|CDD\|236340	PRK08815, PRK08815, GTP cyclohydrolase II RibA.	0
NC_010511.1\|WP_012332232.1\|2633561_2634548_+\|oxidoreductase	gnl\|CDD\|176248	cd08288, MDR_yhdh, Yhdh putative quinone oxidoreductases. Yhdh putative quinone oxidoreductases (QOR). QOR catalyzes the conversion of a quinone + NAD(P)H to a hydroquinone + NAD(P)+. Quinones are cyclic diones derived from aromatic compounds. Membrane bound QOR actin the respiratory chains of bacteria and mitochondria, while soluble QOR acts to protect from toxic quinones (e.g. DT-diaphorase) or as a soluble eye-lens protein in some vertebrates (e.g. zeta-crystalin). QOR reduces quinones through a semi-quinone intermediate via a NAD(P)H-dependent single electron transfer. QOR is a member of the medium chain dehydrogenase/reductase family, but lacks the zinc-binding sites of the prototypical alcohol dehydrogenases of this group. NAD(P)(H)-dependent oxidoreductases are the major enzymes in the interconversion of alcohols and aldehydes, or ketones. Alcohol dehydrogenase in the liver converts ethanol and NAD+ to acetaldehyde and NADH, while in yeast and some other microorganisms ADH catalyzes the conversion acetaldehyde to ethanol in alcoholic fermentation. ADH is a member of the medium chain alcohol dehydrogenase family (MDR), which has a NAD(P)(H)-binding domain in a Rossmann fold of a beta-alpha form. The NAD(H)-binding region is comprised of 2 structurally similar halves, each of which contacts a mononucleotide. A GxGxxG motif after the first mononucleotide contact half allows the close contact of the coenzyme with the ADH backbone. The N-terminal catalytic domain has a distant homology to GroES. These proteins typically form dimers (typically higher plants, mammals) or tetramers (yeast, bacteria), and have 2 tightly bound zinc atoms per subunit, a catalytic zinc at the active site and a structural zinc in a lobe of the catalytic domain. NAD(H) binding occurs in the cleft between the catalytic and coenzyme-binding domains at the active site, and coenzyme binding induces a conformational closing of this cleft. Coenzyme binding typically precedes and contributes to substrate binding. In human ADH catalysis, the zinc ion helps coordinate the alcohol, followed by deprotonation of a histidine, the ribose of NAD, a serine, then the alcohol, which allows the transfer of a hydride to NAD+, creating NADH and a zinc-bound aldehyde or ketone. In yeast and some bacteria, the active site zinc binds an aldehyde, polarizing it, and leading to the reverse reaction.	0
NC_010511.1\|WP_043701109.1\|2626495_2627263_-\|deaminase/reductase	gnl\|CDD\|224896	COG1985, RibD, Pyrimidine reductase, riboflavin biosynthesis [Coenzyme metabolism].	8.58788e-46
NC_010511.1\|WP_012332225.1\|2625947_2626484_-\|cytochrome-b	gnl\|CDD\|225580	COG3038, CybB, Cytochrome B561 [Energy production and conversion].	1.52601e-44
NC_010511.1\|WP_012332234.1\|2635062_2635962_-\|LysR-family-transcriptional-regulator	gnl\|CDD\|223656	COG0583, LysR, Transcriptional regulator [Transcription].	3.96541e-31
NC_010511.1\|WP_043702277.1\|2615556_2616420_-\|cytochrome-c-oxidase-subunit-II	gnl\|CDD\|224537	COG1622, CyoA, Heme/copper-type cytochrome/quinol oxidases, subunit 2 [Energy production and conversion].	1.63582e-75
NC_010511.1\|WP_012332216.1\|2613840_2615469_-\|cytochrome-c-oxidase-subunit-I	gnl\|CDD\|238833	cd01663, Cyt_c_Oxidase_I, Cytochrome C oxidase subunit I. Cytochrome c oxidase (CcO), the terminal oxidase in the respiratory chains of eukaryotes and most bacteria, is a multi-chain transmembrane protein located in the inner membrane of mitochondria and the cell membrane of prokaryotes. It catalyzes the reduction of O2 and simultaneously pumps protons across the membrane. The number of subunits varies from three to five in bacteria and up to 13 in mammalian mitochondria. Only subunits I and II are essential for function, but subunit III, which is also conserved, may play a role in assembly or oxygen delivery to the active site. Subunits I, II, and III of mammalian CcO are encoded within the mitochondrial genome and the remaining 10 subunits are encoded within the nuclear genome. Subunit I contains a heme-copper binuclear center (the active site where O2 is reduced to water) formed by a high-spin heme (heme a3) and a copper ion (CuB). It also contains a low-spin heme (heme a), believed to participate in the transfer of electrons to the binuclear center. For every reduction of an O2 molecule, eight protons are taken from the inside aqueous compartment and four electrons are taken from cytochrome c on the opposite side of the membrane. The four electrons and four of the protons are used in the reduction of O2; the four remaining protons are pumped across the membrane. This charge separation of four charges contributes to the electrochemical gradient used for ATP synthesis. Two proton channels, the D-pathway and K-pathway, leading to the binuclear center have been identified in subunit I. A well-defined pathway for the transfer of pumped protons beyond the binuclear center has not been identified. Electrons are transferred from cytochrome c (the electron donor) to heme a via the CuA binuclear site in subunit II, and directly from heme a to the binuclear center.	0
NC_010511.1\|WP_012332220.1\|2618298_2618772_+\|formate-dehydrogenase-subunit-gamma	gnl\|CDD\|180339	PRK05988, PRK05988, formate dehydrogenase subunit gamma; Validated.	4.21122e-76
NC_010511.1\|WP_012332229.1\|2629319_2630093_+\|helix-turn-helix-domain-containing-protein	gnl\|CDD\|375319	pfam17765, MLTR_LBD, MmyB-like transcription regulator ligand binding domain. This domain is found in a family of actinobacterial transcription factors. The structure shows it has a PAS domain like fold and it is bound to Myristic acid.	1.97877e-33
NC_010511.1\|WP_012332219.1\|2617740_2618139_-\|GFA-family-protein	gnl\|CDD\|226314	COG3791, COG3791, Uncharacterized conserved protein [Function unknown].	1.06522e-32
NC_010511.1\|WP_012332223.1\|2624196_2624439_+\|formate-dehydrogenase-subunit-delta	gnl\|CDD\|378656	pfam11390, FdsD, NADH-dependant formate dehydrogenase delta subunit FdsD. FdsD is the delta subunit of the enzyme formate dehydrogenase. This subunit may play a role in maintaining the quaternary structure by means of electrostatic interactions with the other subunits. The delta subunit is not involved in the active centre of the enzyme.	3.05797e-25
NC_010511.1\|WP_012332233.1\|2634617_2635079_+\|transcription-elongation-factor-GreA	gnl\|CDD\|180535	PRK06342, PRK06342, transcription elongation factor GreA.	1.10961e-56
NC_010511.1\|WP_012332218.1\|2616801_2617710_+\|LysR-family-transcriptional-regulator	gnl\|CDD\|223656	COG0583, LysR, Transcriptional regulator [Transcription].	8.42066e-40
NC_010511.1\|WP_012332228.1\|2628476_2629241_-\|class-I-SAM-dependent-methyltransferase	gnl\|CDD\|369777	pfam08241, Methyltransf_11, Methyltransferase domain. Members of this family are SAM dependent methyltransferases.	3.18622e-22
NC_010511.1\|WP_012332221.1\|2618768_2620328_+\|formate-dehydrogenase-beta-subunit	gnl\|CDD\|224806	COG1894, NuoF, NADH:ubiquinone oxidoreductase, NADH-binding (51 kD) subunit [Energy production and conversion].	0
NC_010511.1\|WP_012332224.1\|2624666_2624951_+\|CRISPR-associated-endonuclease-Cas2	gnl\|CDD\|187856	cd09725, Cas2_I_II_III, CRISPR/Cas system-associated protein Cas2. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas2 is present in majority of CRISPR/Cas systems along with Cas1; RNAse specific to U-rich regions; Possesses an RRM/ferredoxin fold.	2.2203e-18

>NC_010511.1|WP_012332224.1|2624666_2624951_+|CRISPR-associated-endonuclease-Cas2
MLIPSGVNARAPAGRSRLRRVARACLDVGQPVQNSVFACEVDPAQWMALRDRRVGLVDPQRESLRFDRLGAEGRRRTAHVGAKPIPDLDGPLVF
>NC_010511.1|WP_012332223.1|2624196_2624439_+|formate-dehydrogenase-subunit-delta
MSAADQTAKLIRMANQIATFFHPYPEEEAVAGIARHVKDFWTPKMRDALAAACADGAAGLDPLVLRAFGAAPRDAQPRAA
>NC_010511.1|WP_012332222.1|2623348_2624200_+|formate-dehydrogenase-accessory-sulfurtransferase-FdhD
MRPSSGGDAAAETASRVPTLVVAYDDRAAREDTRPLAVEMPVNVIYGSVPYAVMMTTPADLVDFAYGFSLTEGIVRGAEEIRGAAVEPGEGGLRLLVDLAPGRLREHLARKRAMSGRTGCGVCGIDDLADIPRAEARPEAGVRVGIGAVARALVALDGQQVLNRETRAVHAAAWADLDGEILAVREDVGRHNALDKLIGALMRAGTDPAAGFLVITSRCSFEMAEKAASFGAAVLVAISAPTSLAVERARANGLTLAAIARRDTVTIFTRPERLVLAPPEETA
>NC_010511.1|WP_012332221.1|2618768_2620328_+|formate-dehydrogenase-beta-subunit
MTATIFLPRDAVAIGLGAERVAEALTRAALARGLDIRLVRTGSRGMVWLEPLLEVETPEGRIAYGPVRAGDVESLLESGLLAGGAHRLRVGRPEDHPFLARQQRLTFHRCGVIDPVSVADYRAHRGYRGLARALEIGAPATVDAVTLSGLRGRGGAGFPTGIKWNTVMRAEADRKYVVCNADEGDSGTFADRMLMEGDPFTLIEGMTIAGVAVGAARGYIYLRSEYPNACETLRAAIAAGERAGVLGRNVMGSGRDFHLEVRLGAGAYICGEETSLLESLEGRRGIVRAKPPIPALKGLFGRPTLVNNVLSFAAVPWILDHGGEAYAAYGMGRSRGTLPIQLAGNVRQGGLIETAFGITLREVIEDFGGGTRSGRPVRAAQVGGPLGAYFPEGLFDTPMDYEAFAARKGLVGHGGVVVFDDSVDMARQARFAFEFCAVESCGKCTPCRIGAVRGRETMDRLLAGEAPAEPLRLIEDLCEVMTDGSLCAMGGLTPVPVMSAITHFPEDFDRSSRLPLAAE
>NC_010511.1|WP_012332220.1|2618298_2618772_+|formate-dehydrogenase-subunit-gamma
MPGHEPWDAARAAGIIAEHAQLEGATLPILHALQERFGYVDQGAVALIADALNLSKAEVHGCITFYHDFRAEPAGRRVVKLCRAEACQAVGADALHAEILGRYGVGWHGTTADGAVTIEPVFCLGLCACGPAALVDGAPVARLDAEGLAAALTEEAA
>NC_010511.1|WP_012332219.1|2617740_2618139_-|GFA-family-protein
MLTGGCLCGRVRYAADAPAFHETLCHCASCRRAVGAAPVAWFSVARAALRFTGEAPSRYASSPGVVRGFCATCGTSLTYEAEAHAEEIDVTIASLDDPDAAPPRDHTQAAGRPRWTVLADGLPAYPGRRPGR
>NC_010511.1|WP_012332218.1|2616801_2617710_+|LysR-family-transcriptional-regulator
MIDRLEFILALAREQHFGRAAQACGVSQQTLSAGVKQLEERLGVMLVQRGSRFQGFTPEGERVLDWARRIVGDARAMRQEVAALRRGLSGTLRMAAVPTATPIVAALTTPFRARHPAVRFSVQSATSHEIVRQIANLELDAGLTYLENEPLGRVATVPLYREQYRLLTAAEGIYGGRDEVTWAEVAHIPLCLLTPNMQNRRIIDRQLRAVGAEPAPILESNSMIVLVTHVRTAKWASIMPAALAETFKLTERVRAVPITEPDIRHTIGLVVPDRDPMTPLVAAFLAEARALAPQLGRELAGG
>NC_010511.1|WP_043702277.1|2615556_2616420_-|cytochrome-c-oxidase-subunit-II
MGMARAQHRRFGRAILGGAAALAAFLTGTAAFAAGTGQPEPWQMDLQKPVTQVATEIYNFHHLLNVIMLAIVLLVLALLLVVIFRFNERKQPVPSRTTHNTMLEVAWTIVPVLILVAIAIPSFRVLRTQLSDPKADLMVKVVGHAWYWSYEYPKEVGGFGFDANLLEGEDQEKSGQPKLLATDNIMVVPVNKIVKIQVTAADVMHSWAMPSFGFKIDAIPGRLNQFWFKAEREGTYHGQCSELCGQRHAFMPITVRVVSDEAFQAWLTEAKTKYARLDAGAKFASAR
>NC_010511.1|WP_012332216.1|2613840_2615469_-|cytochrome-c-oxidase-subunit-I
MATAASAGHAEAHEHTPPFFQRWFNSTNHKDIGTLYLLFAFSAGIVGAFLSFGIRMEMEQPGLQYFSNPQTYNVFVTGHGLIMVFFMVMPALIGGFGNWFVPLMIGAPDMAFPRMNNISFWLTVAGFLSLVCSLFVEGAPGAVGAGTGWTVYPPLSTDGHPGPAVDFGIFALHLSGAGSILGAINFITTILNMRAPGMTLHKMPLFAWSMLVTAFLLLLSLPVLAGAITMLLTDRNFGTTFFSPQGGGDPILYQHLFWFFGHPEVYIMILPAFGIVSHIISTFSRKPVFGYLAMAYAMVAIGVVGFVVWAHHMYTVGLTLQTQSYFVFATMVIAVPTGVKIFSWIATMWGGSIRFTAAMHWAVGFVFLFTVGGVTGVILANAAVDRYLHDTYYVVAHFHYVLSLGAVFIIFAGVYYWFPKMTGRMIPEWAGKLHFWLAFIGANVLFFPMHFLGLAGMPRRYADYPDAFAGWHYVATMGGHIFALGMVVFVIGVVLAFRSKERAADNPWGEGATTLEWTLSSPPPFHQYETLPVIVDEPSHAH
>NC_010511.1|WP_012332215.1|2612764_2613718_-|protoheme-IX-farnesyltransferase
MTSLTNSLNPARSLAPASNGDVADFFALLKPRVMALVIFTALVGMTVTKSHVNPVIAAVSLLMIAVGAGASGCLNMWWDADVDAVMSRTRTRPIPAGKIRPDEALAFGMTLSVGSVLMLGLAANWLAAGLLAFTIAFYAVIYSMWLKRATAQNIVIGGAAGALPPMIGQAVVTGTVGIEGLVLFLIIFVWTPPHFWALALVKSGDYAKAGIPMMPNVAGPDSTRRQIVAYTLLLAPLGLAPVALGFGGLIYGLVALLGGLAMLALSLQVYHRREGEGADKAAMGLFGFSILYLFLLFSALLAEQGLGLFRPVSQLFG
>NC_010511.1|WP_012332225.1|2625947_2626484_-|cytochrome-b
MPSRYSAAQKFLHWTIAALIFGLVPVAIVMTNIGEGELQNRLFELHKSFGLTALALILARVLVRVSRGAPGLVPGLPAWQRRAARASHLALYGLILLVPLLGWAGTSACCAPVEWFGAVPVTLPISGGMPVGEKILSVHVAAAFLLVTVVAIHVGAALHHHFVRRDATLRRMLPGRGA
>NC_010511.1|WP_043701109.1|2626495_2627263_-|deaminase/reductase
MKAGVDDAGEGWMAAQPWTGLGAGQGTDGVAATLFSPLSEGSTVQPFVIAQLGQSLDGRIATLSGDSKYINRGAALDHLHRLRAHVDAIVVGIGTVLADDPLLTVRRVPGHSPARVIIDPAGRIPPGAQCLREDGARRILVCGPQARVPPGVEVLRMEEPSPFPPRAVIAALGRLGFARILIEGGARTISAFIDAGAIDRLHVMVAPLLLGSGRPGLDLRPIAALREALRPATRSYLLCDGDVLFDCDLRRCAET
>NC_010511.1|WP_012332227.1|2627314_2628427_+|GTP-cyclohydrolase-II-RibA
MSMTVTIVEERLGREQVQVERAVAEMRAGRPVAIAGETCAVAVSAEAVSPELADALQRFGTGAHLVLPAPRLRRIGLANRFEAGCVAMPEIDPERIVSLALRVDGRIDAPVCCPARADAVALELARLAQVIPAVLVVPVPAPPGDLVAVEPGAVEAFRTRQAAALQIVSRAPVPLDGAPETEFVVFRGGEGLRDQVAVVIGRPDPAQPVAVRVHSACLTGDLFGSLKCDCGDQLRGTAKWMAQNGGGIILYLDQEGRGNGLANKIRAYALQAKGYDTYAADEMLGFGLDQRRFDFAAAMLRCLGVASVRVLSNNPEKVAALAAAGLAVVGEQRALGRVTPENARYLAAKRDVAGHALDLGAFACAEVSGS
>NC_010511.1|WP_012332228.1|2628476_2629241_-|class-I-SAM-dependent-methyltransferase
MDRSHETLVTAQFGPQAAAYVESAVHAAGEDLAALDAIAAAAAPRRALDLGCGGGHVAYRLARHARAVTACDLSAEMLAAVAANAAARGLSGIETVEAPAERLPFPDGHFDFVATRFSAHHWRDVEGGLREARRVAARGAPMIVMDGCSPGAALLDTHLQAVELLRDPSHVRDYSAAEWTGMLTRCGFVIEACRTWRVRMDFPTWIARMRTPEAHVAAIRALQALASAPVREHFAIEADGSFLLDVLMVEARAA
>NC_010511.1|WP_012332229.1|2629319_2630093_+|helix-turn-helix-domain-containing-protein
MLGPDERRDLGAFLRAHRERLRPEAPTGRRRTPGLRREELAARAGISATWCAWIEQGREVQVSAQALGRLASALGLTRAERAYLFDLAGRKDPRAAPPDPGADAPASLRAAVAAFASPAYGLDRLWTLCCWNEAARRLFGGWLETAAGPNLLRFVLLDPAARRLIPDWDERVRRVIAEFRADFGHGRADPRARALVAALRRESPLFAVIWEEQDVRDRTGGLRRFLHPEDGPVTFLQHSFSPADRPDCKLVLLVPCG
>NC_010511.1|WP_012332230.1|2630432_2632520_+|HAMP-domain-containing-protein
MRLARLLPTIVLALALLGCGLALWIGLDHERRLDTYAVALTRLKAAKALAEIPATANPERGVIQLQLGTVAPGDTSQSQALTDARKPTDAAFQAAQGAVADLVAAMPALAPVRAELDRQREVLADLRRRSEEVIRTVPIDQRASAAQATIDTTTGMNEAITGMIQAQLEAIAEADGVAYGAGTLAMSVWELRDVGGRSAGILMNLLAQGRPVPEATRTTLTQLDGQVLSIWTRIAAAGARPTTAPALREAIRQATAGYYEPFKALRATLGTEFATGRFSVDVKRFRDVVLPMWGIVLTMRDAAFDSAIARIEDLSARARSEARLAWLTLASMLAIAAAAFWLIRTRVTRPLAAMTASMHRIASGDLDAAIPGVGRRDEIGSMAEAVHVFRDGLARNRTLEAEAEAARRDGEAVRRRAMTELADAFEHSVGGIVQVVSSAATELQATAQHLTGSADHASRQSRTVTAAAGQAAGNVTAVAGAAEELGSSVVEIGRQVEHAAQLASGAVHEATATAAIVADLSAGASRIGAIIEMISGIAGQTNLLALNATIEAARAGEAGRGFAVVAAEVKSLAEQTGKAASEIAGQVSAIQGTMQRAVPAIEGISRTIATINATAAAIAAAVTQQSAATREIVQSVSHASAGTSEVTTTIADVARAAAETGAGADQILASASELARQAEVLRAEMVRFVASVRAA
>NC_010511.1|WP_012332231.1|2632889_2633441_+|hypothetical-protein
MTAPVARLPLLLAAAGLAASALPAVAGGYGYGCASAECYRHVTTPPVYGTVSEQVMVRPARTVTHVVPPVYDTVAEKVMVSPGGRVWQTSYDANGQLVGCWVTTPPQFAVRQRRVLVRPPQVVPEVIPPAYATYQRRVLVEPARSGWVPAGGYGGSVGYPGVYAPAPTTPFGLTAASFSLGGY
>NC_010511.1|WP_012332232.1|2633561_2634548_+|oxidoreductase
MAQFRAIVIEKGEQGQTVALKAFDEADLMEGDVTVRVTHSTLNYKDGLAITGALPVVRRFPMIPGIDFAGVVEQSNHPDWKPGDAVVLNGWGTGETHLGAYAQKARVRGDWLVPLPASFTPQQAMAIGTAGYTAMLCLLALERHGLAPEKGPAVVTGAAGGVGSVAVALLAANGWRVIASTGRSEEEAYLRDLGAAEIIDRAELSKPAKPLAKERWAAGIDTVGGATLANLLSMTKALGAVAACGNAGGMDLPTSVAPFILRGVALLGIDSAMAPLPLRREAWNRLARDLDPAKLAAMTTTIGLDEVLTAAPEILAGRVRGRVVVAIT
>NC_010511.1|WP_012332233.1|2634617_2635079_+|transcription-elongation-factor-GreA
MSIAFVREPEGGEAFEDLPDRPLSPHPNFVTPQGLALIEAELERLHAEHAALSPDDKAGLARTNRDLRYWTARRNSAQVIEPTPGDTVHFGSTVVVEREDGSRQTYRVVGEDEADPARGSIAYVAPLARALTGKLAGDVVRVADHDVEIIEVR
>NC_010511.1|WP_012332234.1|2635062_2635962_-|LysR-family-transcriptional-regulator
MAKTLAWDDFRLIKAIADQRGLAPAAERLGINASTAFRRLGQIEAALGTMLFERHRAGYAPTPAGEAMVRVAARMEEDVAGFSRRLDGQLLAPSGELRVTTADSLFTDLLAPLLARFADRYPEVRLDVVLSNRPLNLSKRDADVALRATDEPPDTLVGRRLATIAWALYGRAEDGTETPPAARRWVSLAQETGAAKVARYVAARADPGRVVLRLDTVSALVAAVEAGIGIAPLACLAGDRRPGLIRLSQPEPDLAAGLWLLTHADLRHAARVRAFLDFVATEIGRLRDCIEGRGVSAPR

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Crispr_ID: NC_010511_15

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_010511_15

2811010-2811104

Orphan

Consensus_repeat	Method
AGGCGCGTTGAGGCTGAACAGCG	CRISPRCasFinder

1 spacers

The CRISPR arrays of NC_010511_15

>merge|NC_010511|15|2811010-2811104|CRISPRCasFinder
AGGCGCGTTGAGGCTGAACAGCGGCGTGCCGAGCAAAAGCGGGAGCGTGACCAGGCTGAAGCCGACGAAGCCAGGCGCGTTGAGGCTGAACAGCG

>NC_010511|15|15|2811010-2811104|CRISPRCasFinder
AGGCGCGTTGAGGCTGAACAGCG	GCGTGCCGAGCAAAAGCGGGAGCGTGACCAGGCTGAAGCCGACGAAGCC
AGGCGCGTTGAGGCTGAACAGCG

Protein	Signature genes	Signature genes Name	Protein_function
NC_010511.1\|WP_012332385.1\|2813155_2813782_-\|hypothetical-protein	unknown	unknown	unknown
NC_010511.1\|WP_012332386.1\|2813963_2814320_+\|hypothetical-protein	unknown	unknown	unknown
NC_010511.1\|WP_018260911.1\|2797832_2798264_-\|universal-stress-protein	unknown	unknown	gnl\|CDD\|366180
NC_010511.1\|WP_026190656.1\|2816455_2817145_-\|molybdate-ABC-transporter-permease-subunit	unknown	unknown	gnl\|CDD\|181841
NC_010511.1\|WP_012332393.1\|2821976_2823335_-\|flagellar-protein-FlgA	unknown	unknown	gnl\|CDD\|226576
NC_010511.1\|WP_012332377.1\|2800533_2800833_-\|hypothetical-protein	unknown	unknown	unknown
NC_010511.1\|WP_018260893.1\|2818847_2820536_-\|HAMP-domain-containing-protein	unknown	unknown	gnl\|CDD\|378936
NC_010511.1\|WP_012332389.1\|2817294_2818806_+\|dihydropyrimidinase	unknown	unknown	gnl\|CDD\|236240
NC_010511.1\|WP_018260892.1\|2821720_2821987_+\|hypothetical-protein	unknown	unknown	unknown
NC_010511.1\|WP_012332382.1\|2808340_2809651_+\|fumarylacetoacetase	unknown	unknown	gnl\|CDD\|162276
NC_010511.1\|WP_168169151.1\|2803321_2804146_-\|AMP-binding-protein	unknown	unknown	gnl\|CDD\|341275
NC_010511.1\|WP_012332380.1\|2805513_2806740_+\|cytochrome-P450	unknown	unknown	gnl\|CDD\|225035
NC_010511.1\|WP_012332388.1\|2815340_2816459_-\|molybdenum-ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|226628
NC_010511.1\|WP_150108640.1\|2812140_2813037_-\|alpha/beta-fold-hydrolase	unknown	unknown	gnl\|CDD\|223669
NC_010511.1\|WP_083784667.1\|2802114_2803098_-\|FkbM-family-methyltransferase	unknown	unknown	gnl\|CDD\|273628
NC_010511.1\|WP_012332391.1\|2821042_2821495_+\|BLUF-domain-containing-protein	unknown	unknown	gnl\|CDD\|377423
NC_010511.1\|WP_012332375.1\|2797111_2797366_+\|hypothetical-protein	unknown	unknown	unknown
NC_010511.1\|WP_012332381.1\|2806979_2808341_+\|homogentisate-1,2-dioxygenase	unknown	unknown	gnl\|CDD\|235421
NC_010511.1\|WP_012332378.1\|2801362_2801737_-\|hypothetical-protein	unknown	unknown	unknown
NC_010511.1\|WP_012332379.1\|2804308_2805517_+\|ABC-transporter-substrate-binding-protein	unknown	unknown	gnl\|CDD\|380550

Protein	Function_ID	Function_description	E-value
NC_010511.1\|WP_026190656.1\|2816455_2817145_-\|molybdate-ABC-transporter-permease-subunit	gnl\|CDD\|181841	PRK09421, modB, molybdate ABC transporter permease subunit.	7.27022e-122
NC_010511.1\|WP_018260911.1\|2797832_2798264_-\|universal-stress-protein	gnl\|CDD\|366180	pfam00582, Usp, Universal stress protein family. The universal stress protein UspA is a small cytoplasmic bacterial protein whose expression is enhanced when the cell is exposed to stress agents. UspA enhances the rate of cell survival during prolonged exposure to such conditions, and may provide a general "stress endurance" activity. The crystal structure of Haemophilus influenzae UspA reveals an alpha/beta fold similar to that of the Methanococcus jannaschii MJ0577 protein, which binds ATP, though UspA lacks ATP-binding activity.	2.68356e-30
NC_010511.1\|WP_012332389.1\|2817294_2818806_+\|dihydropyrimidinase	gnl\|CDD\|236240	PRK08323, PRK08323, phenylhydantoinase; Validated.	0
NC_010511.1\|WP_018260893.1\|2818847_2820536_-\|HAMP-domain-containing-protein	gnl\|CDD\|378936	pfam12729, 4HB_MCP_1, Four helix bundle sensory module for signal transduction. This family is a four helix bundle that operates as a ubiquitous sensory module in prokaryotic signal-transduction. The 4HB_MCP is always found between two predicted transmembrane helices indicating that it detects only extracellular signals. In many cases the domain is associated with a cytoplasmic HAMP domain suggesting that most proteins carrying the bundle might share the mechanism of transmembrane signalling which is well-characterized in E coli chemoreceptors.	7.27195e-43
NC_010511.1\|WP_012332382.1\|2808340_2809651_+\|fumarylacetoacetase	gnl\|CDD\|162276	TIGR01266, fum_ac_acetase, fumarylacetoacetase. This enzyme catalyzes the final step in the breakdown of tyrosine or phenylalanine to fumarate and acetoacetate. [Energy metabolism, Amino acids and amines].	0
NC_010511.1\|WP_168169151.1\|2803321_2804146_-\|AMP-binding-protein	gnl\|CDD\|341275	cd05971, MACS_like_3, Uncharacterized subfamily of medium-chain acyl-CoA synthetase (MACS). MACS catalyzes the two-step activation of medium chain fatty acids (containing 4-12 carbons). The carboxylate substrate first reacts with ATP to form an acyl-adenylate intermediate, which then reacts with CoA to produce an acyl-CoA ester. MACS enzymes are localized to mitochondria.	7.83226e-17
NC_010511.1\|WP_012332380.1\|2805513_2806740_+\|cytochrome-P450	gnl\|CDD\|225035	COG2124, CypX, Cytochrome P450 [Secondary metabolites biosynthesis, transport, and catabolism].	1.32712e-89
NC_010511.1\|WP_150108640.1\|2812140_2813037_-\|alpha/beta-fold-hydrolase	gnl\|CDD\|223669	COG0596, MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [General function prediction only].	6.92056e-24
NC_010511.1\|WP_012332388.1\|2815340_2816459_-\|molybdenum-ABC-transporter-ATP-binding-protein	gnl\|CDD\|226628	COG4148, ModC, ABC-type molybdate transport system, ATPase component [Inorganic ion transport and metabolism].	3.89615e-147
NC_010511.1\|WP_083784667.1\|2802114_2803098_-\|FkbM-family-methyltransferase	gnl\|CDD\|273628	TIGR01444, 2-O-methyltransferase_NoeI, methyltransferase, FkbM family. Members of this family are characterized by two well-conserved short regions separated by a variable in both sequence and length. The first of the two regions is found in a large number of proteins outside this subfamily, a number of which have been characterized as methyltransferases. One member of the present family, FkbM, was shown to be required for a specific methylation in the biosynthesis of the immunosuppressant FK506 in Streptomyces strain MA6548.	2.63413e-21
NC_010511.1\|WP_012332391.1\|2821042_2821495_+\|BLUF-domain-containing-protein	gnl\|CDD\|377423	pfam04940, BLUF, Sensors of blue-light using FAD. The BLUF domain has been shown to bind FAD in the AppA protein. AppA is involved in the repression of photosynthesis genes in response to blue-light.	9.18965e-34
NC_010511.1\|WP_012332393.1\|2821976_2823335_-\|flagellar-protein-FlgA	gnl\|CDD\|226576	COG4091, COG4091, Predicted homoserine dehydrogenase [Amino acid transport and metabolism].	2.08089e-141
NC_010511.1\|WP_012332381.1\|2806979_2808341_+\|homogentisate-1,2-dioxygenase	gnl\|CDD\|235421	PRK05341, PRK05341, homogentisate 1,2-dioxygenase; Provisional.	0
NC_010511.1\|WP_012332379.1\|2804308_2805517_+\|ABC-transporter-substrate-binding-protein	gnl\|CDD\|380550	cd06327, PBP1_SBP-like, periplasmic substrate-binding domain of active transport proteins (substrate binding proteins or SBPs). Periplasmic substrate-binding domain of active transport proteins found in gram-negative, gram-positive bacteria, and archaea. Members of this group are initial receptors in the process of active transport across cellular membrane, but their substrate specificities are not known in detail. However, they closely resemble the group of AmiC and active transport systems for short-chain amides and urea (FmdDEF), and thus are likely to exhibit a ligand-binding mode similar to that of the amide sensor protein AmiC from Pseudomonas aeruginosa. Moreover, this binding domain has high sequence identity to the family of hydrophobic amino acid transporters (HAAT), and thus it may also be involved in transport of amino acids.	2.86032e-179

>NC_010511.1|WP_012332382.1|2808340_2809651_+|fumarylacetoacetase
MADIDATHAATLRSWVPGANGHSDFPIQNLPLGVFSPGDGTPRAGVAIGGRILDLPALLAANLLSGEAALAAEAAGGTTLNRLLALGAGPRRALRARLSALFAEGSPDRDRVAPLLHEASSCRLHLPAAIGDYTDFYVGIHHAENIGRQFRPDNPLLPNYKHVPIGYHGRASSIRPSGTPVRRPRGQSKPPEAGDPVFGPSRRLDYELELGVWIGPGNTLGEPIAIGDAHAHIAGVCLLNDWSARDIQAWEYQPLGPFLAKNFATTISPWIVTAEALAPFRIAQSPRPEGDPRPLPYLTDEVDQRRGAFDLRLEVLLLTPGLRAAGLGPHRISASNTRHMYWTVAQMVAHHTGGGCNLQPGDLLGTGTISGPDRDACGSLLEATLGGREPLRLASGEERRFLEDGDEVILRARGVRDTFAPIGFGECRAELLGAAP
>NC_010511.1|WP_012332381.1|2806979_2808341_+|homogentisate-1,2-dioxygenase
MNQHGRLDPAGTIAAAQIHPGYMSGFGNGFETEALPGALPIGRNSPQICPYGLYAEQLSGSPFTAPRTANERSWLYRIRPTVMHWGDFRKVDARLWLTAPAELVDLPPAPLRWDPVAIPSEPLSFVEGICTVTTAGDAGAQAGMGAHFYFATRSMPDEYFSNADGEMLVVPQEGALRWRTEFGIIDVEPGEVCVIPRGVKVAVDLLGGPARGYVCENYGGAFTLPERGPIGANCLANQRDFLTPVAAYEDRDAPGTMLVKWGGALWAAEIDHSPLDVVAWHGNYAPYKYDLRKFSPVGPILFDHADPSIFTVLTSPSETPGTANIDFVIFSDRWLVAENTFRPPWYHLNVMSEFMGLVYGVYDAKTGGGFRPGGASLHNTLLPHGPDVDAFERASNVDLKPHKLEGTLAFMFETRFPQKVSRFAAETPARQKDYAAYGRKLAKHFDPNRAEAR
>NC_010511.1|WP_012332380.1|2805513_2806740_+|cytochrome-P450
MSAVDAAERARRFDLRRLPEGFIEDPYPVYAALRTHAPVHVFAPGQVLLTRYVDLERVYKDAATFSSDKVVEFGAKFGPSPLYAHHTTSLVFNDPPRHTRVRRIIAGALAPRAIASMEASIVALVDGLLDAAEERGRIDLIEDFAAAIPVEVIGNLLGVPRAEREPLRAWSLAILGALEPVLDAATMEAGNRAVTEFLDYLKRLVAERRRRLGDPERDILTRLIQGEMEGERLSPEELLQNCIFILNAGHETTTNLIGNGLHLLTQWPEARERLLSEPDLLRRAVEEMLRFESSNQLGNRIAAKPFALGGRDFPAGTQITLGIGAANRDPDQFPDPDRFDVAREPNRHLAFASGIHQCVGMTVARLEGRIAIGRFLARFPSYALDGPPLRSRRVRFRGFSRLPARVEA
>NC_010511.1|WP_012332379.1|2804308_2805517_+|ABC-transporter-substrate-binding-protein
MKRSAAGLRRAALALSLLAGPAAAQVSDDVVRIGVLTDLSGPYADSGGRGSVIAAEMAAADAGGWILGKPVEIVSADHQNKPDVASSIARRWYDVEKVDAVVDLPVTAIALAVQAVSKEKNRTVMITAAATSDLTAKTCSPTSSHWTDDTHALTAGTARAVFERGGRSWYFITVDHAFGHALQKEATAVVESLGGKVVGTSRHPIATADYSSFLLQAQSSGADVVAFASVGDDFTKAIKQANEFGLTQGGQTLTGFLVYITDIKGLGLPVAHGLTFSSAFYWDQSEPARAFAKRFQDKTGVMPTKNQALIYTAVTHYLKAVAQAGTDEALAVNKAMRAMPVAFFGHPATLRADGRLLYDPVLYRVKGERESKGPWDLYEAVRSIPQGEAFLPINPACAGQNG
>NC_010511.1|WP_168169151.1|2803321_2804146_-|AMP-binding-protein
MASAVARAVPRRNDAGAERADAAARGHHADLVAGFCWAIPQRYIIGADDCDRHAPGDPLALIDLDGADATQHFGFDDLRPASNRFANRLATQSLRRGDRLGALLPPSPETAIAHLASSRAGLITVPLFTLFGPGRAPPSARRRRRASGGDGPCRGREAGFPARPAAGPGAGLDRGRTGSGPGGEAERQAGRGCLTTRERRRDRVCDRLVEVPLQRVAQNRLQVRPCSSVVSCTRQANRPRWCPGMSKRTSHSSRPRVRRRSASRRRRSLSMSAD
>NC_010511.1|WP_083784667.1|2802114_2803098_-|FkbM-family-methyltransferase
MKAQILQLFSWFVRKLPERRKIQIVKTLADDQEFARLHARYAIAAFAGPAGVTGVASRGVSGTIVSQPYDFSVHRAYSEKGDWAKTTVDKLKEFFDKNGGVGYYLDIGANIGLTTIPIAQSYPNVHCFAFEPEPHNFMNLEINTKINCRHANYKLFRLALFKENSNLQFEIAPENLGDHRIRIGGNFIGDIGEHLRPVINVEAVPLNDFAAYIKTPLAVKIDVQGAEPFVFEGGKDVLKKAGLIILEWWPYTMKRMKADPDIIFEFIKSNFASCSIAAAEGTGESRSYAAQDAINILKSNYDKEAESDKIYYDLTMTTPVDKNHILR
>NC_010511.1|WP_012332378.1|2801362_2801737_-|hypothetical-protein
MSRRNPRRAYDEQGRAIPPPTIGWIRSEEGDRTAFVHANATHCGHEAVISTDRFPDSLPFPDIALHPRCSACGAKSVGVMRDVVGIHRRLQAHRVEYGQRGDPAAGDRVTGRDTPWPDKSGSRI
>NC_010511.1|WP_012332377.1|2800533_2800833_-|hypothetical-protein
MSLRSQYEQAVRDLREHAAEMRRRGASAEAIARAMHAERRRLASLFKEQTPEPHRTRIYERTLRVYGNEIGPSIESLRAMGKSWEAIIESATRPGLPVE
>NC_010511.1|WP_018260911.1|2797832_2798264_-|universal-stress-protein
MYQHILVPTDGTSISASAVKNAVSLAKTVGAKVTVLTVVARFPALPLGASNPYVDEFTRHAHADADRRLTEAEQEAKRVGVSCEVVKVEDRQPYEAIIETAEARGCDLIAMASHGRRGFSALVIGSETMKVLTHSKLPVLIYR
>NC_010511.1|WP_012332375.1|2797111_2797366_+|hypothetical-protein
MTVKLIAVSIGLSVLALASPAVPLDMGTLAEQRACTPDAISLCGKHIPYPGRVRACLLSKRESLSPACRSAIASYEARTAAPRQ
>NC_010511.1|WP_150108640.1|2812140_2813037_-|alpha/beta-fold-hydrolase
MLKALEREPSSRPPGRFVDVDGLRVHYIVRGKGRPVVLIHGNGTMAEDFVISGLLDQLAKKYRVIAIDRPGFGHTERPRHRIWTASAQARLLERVLAQLNVERPVIVGHSWGTIVSLALATQTQSDLRGLVLLAGYYYPSRRTDVALITPLAVPGMGDVARALMPDAIGHLLAPQVFRHVFKPQPVPARFMARFPVAISIHPTQARASAEDTATMNAAAALLERHYPTLRLPVAILAGDADAVVDARAQSRRLQEDVVGSTLLILRGQGHMIHYSARAKIGQAIDAHMALTNKSLKRR
>NC_010511.1|WP_012332385.1|2813155_2813782_-|hypothetical-protein
MDEAQLEDETTFNMLCDVALVEPNQRGRRVFDGFLGDRLASLDSPERDLAPCLADAFFSIFRVAGRHEHSGVWVEDLLASRRRLWLLDERVEASAPENLVIAVRVFDAGPSYAGVAIVVQPDEDMAAFCTAAAARCDRMPARHALAAGLYRDGILPRSMHGAAVTDILAALAEAWMPGSGQGSGAKTALSHRQHQAASAGRRNGFVSV
>NC_010511.1|WP_012332386.1|2813963_2814320_+|hypothetical-protein
MSSIRERFRGQWRITETGTWDNDYLDMIEPAFIAFEPGGTGEFRFGVVVASLDCSYSQTDVGFRFHGSDEGTEVWGDGWAEFDRPDAISGEIAFWNGDETTFKARRWPGSSCVWALRG
>NC_010511.1|WP_012332388.1|2815340_2816459_-|molybdenum-ABC-transporter-ATP-binding-protein
MITVEASHALGHFSLDAAFTAAGRVTALFGRSGAGKTSLVNVVAGLLRPRAGRVVVDGAVLLDTAAGICVPVHRRRVGYVFQDARLLPHLSVRQNLLFGRWFAGSGSAAPGRAEPSLGAVADLLGLGPLLARRPAGLSGGERQRVAIGRALLAHPRLLLMDEPLSALDEARKTEILPYLERLRDEARVPIMFVSHAVAEVARLADTVVVLEAGRVAASGPADAILRRSDLLPGPQAAEAGALLELRVAGHDPDFGLTRLEGAVGSLTVPRLDLPVGSGVRVRVRARDVLVALERPRGLSARNHLPGTIRTIAQQPGAYATVEIACGAALLSASLTRHAVHELGLRPGLEVFALVKGVAFDPATIASGAEVAI
>NC_010511.1|WP_026190656.1|2816455_2817145_-|molybdate-ABC-transporter-permease-subunit
MPVLTPDEWSALRLSLQVAGVATLASLVPGLLVALLLARGRFRGRALLDGLVHLPLILPPVVTGYLLLLGFGRRGLFGAALAEIGIVFSFRWTGAALACAVMGFPLMVRAMRLSIEAIDPRLEQAAATLGAPPLGVFAVVTLPLALPGILAGAVLAFAKAMGEFGATITFVSNIPGETQTLPSAIYALTQVPGGEDGALRLTLVSVAVSMTALLASEGLARRAKRRLGA
>NC_010511.1|WP_012332389.1|2817294_2818806_+|dihydropyrimidinase
MPPASHDRDFDLVVRGGLLATAAETFEADLAIRDGRIAAIGRALRPGAEEIDAKGLVVTPGGLDPHCHIEEPSEAGGVQEESFASGSAAALAGGTTSFICFVPQWKGHPIARTAPGYEARARASRADYGFHQIITDPTPEVLEREVPALVARGIRSLKVFLTYDPLRLTDGQYLEVLATARRLGALVTVHCENFDAIGWRIRALLAAGLTDPLQHAWARPPVVEREATHRAIALAELVDQPIQIFHVSCDEAAEEIARARARGVKVWGETCPQYLTLSTEDLARPDFEGAKVVCSPALRAPAERERIWARIADGTLDIVSSDHCGFSFATAKRDPGSSGYGQGGAEARPDGMPAFNAIPNGVPGIETRLPLLFSEGVSKGRIDLPTFVRLTSANAARLFGLAGRKGTLAPGADADLVLWDPSAERRIRNAALHHAIDYTPWEGLAVTGWPATVIRRGEVAVRDGAVLAEPGSGRFLARGPYPLVRPTGRVPDGFDAAAVPPRS
>NC_010511.1|WP_018260893.1|2818847_2820536_-|HAMP-domain-containing-protein
MSVQPLSIRTKLIAAFTLLGLVIVGLGALGLVSTQRMREQSAAVEKDWLPGVRALGEIDTRAARLNGVLFRHILATDPALTATIEKDLVRFGTWVEEAKAKYERLINAPEERALYDAYRRTAEAFEAERQIVLDLSRRGEKAAAFQHYETKAIGPRRAMSDALEKLVAYTNDGAERAQAMSEGAYDTARTMAWLGIAAGLALAVALAGLIVRGVTRGIASVVAPMQALAAGDVSAAIPHRGERTELGTLADGVQVFKDSLLRMRALEEDSQAARAGAEAQRRAAMREMADGFEQAVGSIVGLVSAAASQLQATAQGMAGAATMTAEQSTSVAAAAEEAATNVNTVAAAAEELGASVREISRQVGGSAELAREAVQEAGVTAESVRELSAAMGKIGDVVTMITAIAGQTNLLALNATIEAARAGEAGRGFAVVAAEVKELANQTARATEEITAQIARIQGTTGQTVSAIGAITRRIEEISRVATSIAAAVEEQGAATQEIVRSVAQAAEGTGEVTANVGGLAAAAGETGAAASQVLAASSDLSRQSDQLGREVNDFLARVRAA
>NC_010511.1|WP_012332391.1|2821042_2821495_+|BLUF-domain-containing-protein
MIHQLVYYSRNTVQGGDRAMLTNLREIVSASQRNNGRDGITGFLIFDKTWFVQILEGDRARVSDTYARIGRDTRHSAATIVTVQNVPARLFPNWTMGGAMRNPEMQEVFLAHGIGGPLDPVRMSARQILGLAVDLDAFERAKREPQRLAG
>NC_010511.1|WP_018260892.1|2821720_2821987_+|hypothetical-protein
MSKSMVGICAVLLSVAAATASRAEGTAAQRAACTPDVFRLCSSEIPDVGRIKACLRRERVNLSSGCQAVFNEIDRTAAPGAVVQNVRS
>NC_010511.1|WP_012332393.1|2821976_2823335_-|flagellar-protein-FlgA
MSLHHALAARAQAGRPVRVALIGAGKFGSMFLSQAPRTPGLHVLGIADLNPQRARAATARVGWPAEQVAARSVAEALRGGGTFVTDDAAALIAADGVDVVIEATGHPGAGIRHALLCCRHGRHVVMVNVEADALAGPLLARQAAEAGILYSFAYGDQPALIAELVDWARTAGFPVVCAGKGTKYLPAYHASTPDTVWGHYGFTPEQVAAGDFNPQMFNSFLDGTKSALEMAAVANACRLDPGPDGLAFPPCGVDDLPSVLRPREAGGALPFAGTVEVVSSLERDGRPVFRDLRWGVYVVIEAPSDYVRRCFAEYGLRTDASGRYAAMYKPYHLIGLELGLSVASLVVRGEPTGATREFRADVVATAKRDLRAGDRLDGEGGHTVYGRLMPASASLAAGGLPIGLAHGFTLTRPVPAGSLVRWEDVSFNSEDPAVRLRREMETLFAREAGVRT

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Crispr_ID: NC_010511_16

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_010511_16

3015488-3015591

Orphan

Consensus_repeat	Method
CGCGGCGCTTGAGCGAGGCCGACATCCGCATGGCGA	CRISPRCasFinder

1 spacers

The CRISPR arrays of NC_010511_16

>merge|NC_010511|16|3015488-3015591|CRISPRCasFinder
CGCGGCGCTTGAGCGAGGCCGACATCCGCATGGCGACGCAATCCGTCGGATCGCGGATCACGAGCCCGCGCGGCGCTTGAGCGAAGCCGACATCCGCATGGCGA

>NC_010511|16|16|3015488-3015591|CRISPRCasFinder
CGCGGCGCTTGAGCGAGGCCGACATCCGCATGGCGA	CGCAATCCGTCGGATCGCGGATCACGAGCCCG
CGCGGCGCTTGAGCGAAGCCGACATCCGCATGGCGA

Protein	Signature genes	Signature genes Name	Protein_function
NC_010511.1\|WP_012332554.1\|3010255_3011596_-\|cell-wall-hydrolase	unknown	unknown	gnl\|CDD\|226296
NC_010511.1\|WP_012332559.1\|3019925_3020984_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|379751
NC_010511.1\|WP_012332556.1\|3014681_3015341_-\|L,D-transpeptidase	unknown	unknown	gnl\|CDD\|224294
NC_010511.1\|WP_012332548.1\|3002959_3003880_+\|ABC-transporter-permease	unknown	unknown	gnl\|CDD\|224094
NC_010511.1\|WP_012332555.1\|3011855_3014531_-\|pyruvate,-phosphate-dikinase	unknown	unknown	gnl\|CDD\|236446
NC_010511.1\|WP_012332563.1\|3024230_3024992_-\|SDR-family-oxidoreductase	unknown	unknown	gnl\|CDD\|180773
NC_010511.1\|WP_012332549.1\|3003876_3004920_+\|ATP-binding-cassette-domain-containing-protein	unknown	unknown	gnl\|CDD\|236898
NC_010511.1\|WP_043702381.1\|3007697_3009785_-\|methyl-accepting-chemotaxis-protein	unknown	unknown	gnl\|CDD\|214599
NC_010511.1\|WP_043701185.1\|3025544_3028439_-\|multidrug-ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|224055
NC_010511.1\|WP_012332561.1\|3022180_3022624_+\|glyoxalase	unknown	unknown	gnl\|CDD\|319916
NC_010511.1\|WP_012332547.1\|3002001_3002955_+\|ABC-transporter-permease	unknown	unknown	gnl\|CDD\|223674
NC_010511.1\|WP_043701180.1\|3025012_3025459_-\|Crp/Fnr-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|223736
NC_010511.1\|WP_012332558.1\|3018137_3019685_-\|acetolactate-synthase-large-subunit	unknown	unknown	gnl\|CDD\|236063
NC_010511.1\|WP_012332566.1\|3028753_3028957_-\|hypothetical-protein	unknown	unknown	unknown
NC_010511.1\|WP_012332550.1\|3004923_3005934_+\|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|223521
NC_010511.1\|WP_043702384.1\|3015612_3017922_-\|EAL-domain-containing-protein	unknown	unknown	gnl\|CDD\|227334
NC_010511.1\|WP_012332552.1\|3006482_3007571_+\|membrane-protein	unknown	unknown	gnl\|CDD\|274596
NC_010511.1\|WP_012332562.1\|3022900_3024199_+\|pilus-assembly-protein-TadG	unknown	unknown	gnl\|CDD\|379164
NC_010511.1\|WP_012332551.1\|3006165_3006486_+\|(2Fe-2S)-ferredoxin-domain-containing-protein	unknown	unknown	gnl\|CDD\|239278
NC_010511.1\|WP_012332560.1\|3021111_3022104_+\|fumarylacetoacetate-hydrolase-family-protein	unknown	unknown	gnl\|CDD\|375715

Protein	Function_ID	Function_description	E-value
NC_010511.1\|WP_012332554.1\|3010255_3011596_-\|cell-wall-hydrolase	gnl\|CDD\|226296	COG3773, SleB, Cell wall hydrolyses involved in spore germination [Cell envelope biogenesis, outer membrane].	1.23973e-36
NC_010511.1\|WP_012332559.1\|3019925_3020984_+\|hypothetical-protein	gnl\|CDD\|379751	pfam15887, Peptidase_Mx, Putative zinc-binding metallo-peptidase. This family has a highly conserved HHExxH motif with a highly conserved ED pairing downstream. HExxH is indicative of a zinc-binding metallo-peptidase.	6.36113e-164
NC_010511.1\|WP_012332556.1\|3014681_3015341_-\|L,D-transpeptidase	gnl\|CDD\|224294	COG1376, ErfK, Uncharacterized protein conserved in bacteria [Function unknown].	1.5571e-47
NC_010511.1\|WP_012332548.1\|3002959_3003880_+\|ABC-transporter-permease	gnl\|CDD\|224094	COG1173, DppC, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism].	5.4998e-84
NC_010511.1\|WP_012332555.1\|3011855_3014531_-\|pyruvate,-phosphate-dikinase	gnl\|CDD\|236446	PRK09279, PRK09279, pyruvate phosphate dikinase; Provisional.	0
NC_010511.1\|WP_012332563.1\|3024230_3024992_-\|SDR-family-oxidoreductase	gnl\|CDD\|180773	PRK06949, PRK06949, SDR family oxidoreductase.	6.53547e-67
NC_010511.1\|WP_012332549.1\|3003876_3004920_+\|ATP-binding-cassette-domain-containing-protein	gnl\|CDD\|236898	PRK11308, dppF, dipeptide transporter ATP-binding subunit; Provisional.	2.47483e-130
NC_010511.1\|WP_043702381.1\|3007697_3009785_-\|methyl-accepting-chemotaxis-protein	gnl\|CDD\|214599	smart00283, MA, Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). Thought to undergo reversible methylation in response to attractants or repellants during bacterial chemotaxis.	2.11709e-38
NC_010511.1\|WP_043701185.1\|3025544_3028439_-\|multidrug-ABC-transporter-ATP-binding-protein	gnl\|CDD\|224055	COG1132, MdlB, ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms].	1.25654e-39
NC_010511.1\|WP_012332561.1\|3022180_3022624_+\|glyoxalase	gnl\|CDD\|319916	cd07253, GLOD5, Human glyoxalase domain-containing protein 5 and similar proteins. Uncharacterized subfamily of VOC family contains human glyoxalase domain-containing protein 5 and similar proteins. The vicinal oxygen chelate (VOC) superfamily is composed of structurally related proteins with paired beta.alpha.beta.beta.beta motifs that provide a metal coordination environment with two or three open or readily accessible coordination sites to promote direct electrophilic participation of the metal ion in catalysis. VOC domain is found in a variety of structurally related metalloproteins, including the bleomycin resistance protein, glyoxalase I, and type I ring-cleaving dioxygenases. A bound metal ion is required for protein activities for the members of this superfamily. A variety of metal ions have been found in the catalytic centers of these proteins including Fe(II), Mn(II), Zn(II), Ni(II) and Mg(II). The protein superfamily contains members with or without domain swapping. The proteins of this family share three conserved metal binding amino acids with the type I extradiol dioxygenases, which shows no domain swapping.	2.79999e-40
NC_010511.1\|WP_012332547.1\|3002001_3002955_+\|ABC-transporter-permease	gnl\|CDD\|223674	COG0601, DppB, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism].	2.31196e-114
NC_010511.1\|WP_043701180.1\|3025012_3025459_-\|Crp/Fnr-family-transcriptional-regulator	gnl\|CDD\|223736	COG0664, Crp, cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms].	5.88841e-25
NC_010511.1\|WP_012332558.1\|3018137_3019685_-\|acetolactate-synthase-large-subunit	gnl\|CDD\|236063	PRK07586, PRK07586, acetolactate synthase large subunit.	0
NC_010511.1\|WP_012332550.1\|3004923_3005934_+\|ABC-transporter-ATP-binding-protein	gnl\|CDD\|223521	COG0444, DppD, ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism / Inorganic ion transport and metabolism].	9.42903e-150
NC_010511.1\|WP_043702384.1\|3015612_3017922_-\|EAL-domain-containing-protein	gnl\|CDD\|227334	COG5001, COG5001, Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain [Signal transduction mechanisms].	3.8376e-132
NC_010511.1\|WP_012332552.1\|3006482_3007571_+\|membrane-protein	gnl\|CDD\|274596	TIGR03476, HpnL, putative membrane protein. This family of hydrophobic proteins is observed in two distinct contexts. It is primarily found in the presence of genes for the biosynthesis and elaboration of hopene where we assign the gene symbol HpnL. In a subset of the genomes containing HpnL a second, often plasmid-encoded, homolog is observed in a context implying the biosynthesis of 2-aminoethylphosphonate head-group containing lipids.	1.02712e-60
NC_010511.1\|WP_012332562.1\|3022900_3024199_+\|pilus-assembly-protein-TadG	gnl\|CDD\|379164	pfam13400, Tad, Putative Flp pilus-assembly TadE/G-like. This is an N-terminal domain on a family of putative Flp pilus-assembly proteins. The exact function is not known. The Flp-pilus biogenesis genes include the Tad genes, and some members of this family are putatively assigned as being TadG.	2.09685e-05
NC_010511.1\|WP_012332551.1\|3006165_3006486_+\|(2Fe-2S)-ferredoxin-domain-containing-protein	gnl\|CDD\|239278	cd02980, TRX_Fd_family, Thioredoxin (TRX)-like [2Fe-2S] Ferredoxin (Fd) family; composed of [2Fe-2S] Fds with a TRX fold (TRX-like Fds) and proteins containing domains similar to TRX-like Fd including formate dehydrogenases, NAD-reducing hydrogenases and the subunit E of NADH:ubiquinone oxidoreductase (NuoE). TRX-like Fds are soluble low-potential electron carriers containing a single [2Fe-2S] cluster. The exact role of TRX-like Fd is still unclear. It has been suggested that it may be involved in nitrogen fixation. Its homologous domains in large redox enzymes (such as Nuo and hydrogenases) function as electron carriers.	0.000892145
NC_010511.1\|WP_012332560.1\|3021111_3022104_+\|fumarylacetoacetate-hydrolase-family-protein	gnl\|CDD\|375715	pfam18288, FAA_hydro_N_2, Fumarylacetoacetase N-terminal domain 2. This is domain is found in the N-terminal region of Fumarylacetoacetate (FAA) hydrolase (pfam01557). Family members of this domain include Pseudogulbenkiania ferrooxidans and Cupriavidus gilardii.	1.87765e-25

>NC_010511.1|WP_012332556.1|3014681_3015341_-|L,D-transpeptidase
MTPRRLIPLLLASLSLAACQARGPAQVAVTGVAATDEDAAWYIGTMPDQPFDVPLVDRGRIDPKYRRQVVAYAGPEKPGTIVVDIDERLLYLVQDGGEAIRYGVGVGKLGFSWKGTATIGRKGVWPDWGPTRTMVGLNPDLPRSRKGGLDNPLGARALYLYQGGRDILFRIHGTNEPWSIGEQMSSGCVRMLNEDIVDLYGRVPVGTTVLVKRHGRYRV
>NC_010511.1|WP_012332555.1|3011855_3014531_-|pyruvate,-phosphate-dikinase
MAKWVYTFGDGKAEGQSSMRNLLGGKGANLAEMSNLGLPVPPGFTITTEVCTYFYDHGREYPPELKDQVDAALEAVGGLTGRRFGDSETPLLVSVRSGARASMPGMMDTVLNLGLNDVTVEALARGAGDPRFAYDSYRRFITMYANVVLGVEHHTFEEALEHYKETKGLDLDTDLSAQDWKHLIGEYKSIVKRELGQDFPQDPQAQLWGAIGAVFGSWRNPRANKYRELHAIPESWGTAVNVQAMVFGNMGDTSATGVAFTRNPSTGERALYGEFLINAQGEDVVAGIRTPQDITEAARIESGSDKPSMERAMPEAYAELVRIYGLLEKHYRDMQDMEFTVENGKLWMLQTRNGKRTAKAALRIAVELAGEGLITRQEAIGRVEPASLDQLLHPTIDPKAERRVIATGLPASPGAACGEIVFNSEEAEAARKAERKVILVRVETSPEDIHGMHAAEGILTTRGGMTSHAAVVARGMGKPCVSGAGAIRVDYNARTLSVGGVTLKAGDLVTIDGSNGQVIQGEMPMLEPELSGDFATLMGWADEVRTMKVRANAETPADARAARTFGAEGIGLSRTEHMFFDEGRITAVREMILSDDAEGRRAALAKLLPYQRADFVELFTIMSGLPVTIRLLDPPLHEFLPKEEEVAAFAAETGLPADKLRRRMTELHETNPMLGFRGCRLAILFPEIAEMQARAIFEAAVEAATRTGKPVIPEVMVPLVFTKAEFDLVKARIDAMGKAVAQETGASVEYQVGTMIELPRAALRAGDIAQTAEFFSFGTNDLTQTTLGISRDDAGTFLGPYTKSGILSSDPFVSIDQEGVGELVRLGVERGRAVRPGIKLGICGEHGGDPASIAFCQEVGLDYVSCSPYRVPIARLAAAQAALSIRPRGEA
>NC_010511.1|WP_012332554.1|3010255_3011596_-|cell-wall-hydrolase
MRWIGAATAPWLVAGGVLVSFTAAAGVDSSFGASTVALLSAHASPPLPPSGLVPPSGLVPPSGLVPPSGLVPPSGLVPPSGLVPPSGLVPPSGLVPPSGLVPPSGLVPPSGLFAEPLDAAPLHPDLKSHAGPTPLPQRAAKADALAPGRQESARRRLASLRRGWLGGAGSGVAAALTPGPATWTPDPDETGFVPFPPGGSPPVGGERSSESSPSSAASDETRGASTGGRTQDARQDGATPAVPRAVALSSTTPAPADAIPIEVAAAPVVGGLPSSRLDARPGLTHAARISPEVLPTEEARRRYAALITPDNAEKEQRCLAEAVYFEARGEPEQGQAAVAQVVLNRAKSGLYPSNICGVVYQNRHRYLGCQFSFACEGRSLRITDESAWTTATRVAREVVEGRTYLADVGGATHYHADYVRPRWSRRLKKMDVIGRHIFYQLKPGQT
>NC_010511.1|WP_043702381.1|3007697_3009785_-|methyl-accepting-chemotaxis-protein
MRLARLLPTIVLALALLGCGLALWIGLGHQQHLDTYAVTLTRLKAAKALADIPAAADPERGLMQLQLGTVAPGDTSQSQALIDARKPADAAFRAAQAAVGQLVEALPELAPVRAELDRQREVFADLRRRSEEMIRGVPIAQRGNAAEAAIDTTSRMNEAIIGMIHAQLAAIAQVDGVAFGAGDLALTVWELRDVAGRIGGVLQNLIVQGKPVPEATRTTLTQLDGQLHPIWTRIAATGARPTTAPALREAIRQATAGYHEPFKALRASLGTEFATGQFSMDAPRFREVTLKMWRIVLEARDAAFDSAIARIEDLSARARSEARLAWLTLASMLAIAAAAFWLIRTRVTRPLAAMTASMHRIASGDLDAAIPGVGRRDEIGSMAEAVHVFRDGLARNRTLEAEAEAARRDGEAVRRRAMTELADAFEHSVGGIVQVVSSAATELQATAQHLTGSADHASRQSRTVTAAAGQAAGNVTAVAGAAEELGSSVVEIGRQVEHAAQLASGAVHEATATAAIVADLPAGASRIGAIIEMISGIAGQTNLLALNATIEAARAGEAGRGFAVVAAEVKSLAEQTGKAASEIAGQVSAIQGTMQRAVPAIEGISRTIATINATAAAIAAAVTQQSAATREIVQSVSHASAGTSEVTTTIADVARAAAETGAGADQILASASELARQAEVLRAEMVRFVASVRAA
>NC_010511.1|WP_012332552.1|3006482_3007571_+|membrane-protein
MSGGPPAATRRLARALMRRVPLIGALAGLVLALWLVSVHDLSAVATAFGRIGPAGLAAVVLVRALVVLLCGLAWARVAGVPQIGAGPFVLLRFVREGVNVLLPVASVGGEVLGGRLLTFWGVAGPVAAAGIVVDLFFQIVGLALFALFGMVLLLRVEGEQAAQVAAWCAQGLALAALVLGGFYAVQRFGGAGAVERRIAALGRRFMREASGTAPEIGVQQALDALWDLRRWRVLAEGFLLHLAAWFAGALEIWIALTCIGVEHVSLTEALVLESLSQAIRSAAFPVPSGLGVQEGGLVLLGGLFGVDPGTALALSLVKRVPDVVLGLPSLLLWQAIEGRREAVARPAACGARMAGSLPRVEG
>NC_010511.1|WP_012332551.1|3006165_3006486_+|(2Fe-2S)-ferredoxin-domain-containing-protein
MSASDSAVRRPRAAAAPWNDLVVVCAKCAKRQGLGGRVRKDLKRALKRARPERKVRVVETGCLGLCPKRSLTFATPASLRAGRLLVLDPATEAETMAEILVPEPHR
>NC_010511.1|WP_012332550.1|3004923_3005934_+|ABC-transporter-ATP-binding-protein
MNAPLRSPEAAAADALVEVRGLTVDFLGGRKPVRAVGGVDLDLRAGDALALLGESGSGKSVTLRALMRLLPERRTRIGGSLRVDGQDVLALGRRSLAAYRGGTVSMIFQDPGLALDPVYRIGDQIAEAVVRHEGASFAKGRARALELFERVHIPSASRRLDAYPHEMSGGMRQRAMIALALACKPKLLLADEPTTALDATVQIQILLLLRELQRDLGLAVIFVTHDVGVAVQVADRVAVMYGGHLVEVGASGEVIGTPAHPYTQGLLASRITPASPKGVRLATIPGSPPDLADPPPGCPFEPRCARAAPPCRAGLPPRIAVAPGHAARCVRLGASP
>NC_010511.1|WP_012332549.1|3003876_3004920_+|ATP-binding-cassette-domain-containing-protein
MSETLDPRDRGGPAQPLLSVRGLVKHFGSKGGLFGKGPVVRAVDGVDFDILKGETLGVVGESGCGKSTTARLLMQIIAPDQGDVVFDGELLGSRALDLKSYRRQVQMVFQDSYASLNPRLTVEETVAFGPQSHGLSRRAALGRAHDLLRRVGLEPRRFGARYPHEVSGGQRQRVNIARALALEPRLLILDEAVSALDKSVEAQVLNLLTDLKREFGLTYMFISHDLNVVRFMSDRVMVMYLGKVAELGPADAILASPRHPYTAALLASQPSTDPGARIEEAPLTGDPPNPINPPPGCRFHTRCRFAAAICGAREPGLDEVAPGHAAACHRAVAGSGHPEAPALPMAA
>NC_010511.1|WP_012332548.1|3002959_3003880_+|ABC-transporter-permease
MTPPTTLASADPGAAAPAESAEAPVQAGRGYWGSVLSRLLRDRVAMAALLVILLIVLAAVFAPLIAPMDPFKGSMIRRLKPVGDATYLLGSDELGRDMLSRLLYAGRLSLFMGVLPVVIAFFVGSGLGILAGYAGGWANTLIMRVVDVFFAFPSVLLAIALSGALGAGILNSIVSLTVVFVPQITRVAESVTVQIRNRDYVEAARISGANPLRVVRVQVLGNVLGPVFVYATSLISVSMILASGLSFLGLGVKPPEPEWGLMLNTLRTAIYVNPLVAALPGAMIFVTSISFNLLSDGLRSAMEVRS
>NC_010511.1|WP_012332547.1|3002001_3002955_+|ABC-transporter-permease
MLSFVLKRVAYAAPVALGVSLVCFLLVHLAPGDPLSAILPVDATAEMQAQMRAAYGFDKPLPVQYGLWLWKVLHGDLGTSIATGRPVAAEVGRAVTNSLILAAVATLIGFTFGTFFGFVAGYARDSWLDRLASAVAVFGVSVPHYWLGIVLVIVFSATLGWLPPTGAGPQGSGDWWPDAEHLRYLVLPAITMSVIPMGVISRTVRALVGDILHQDFVQALRAKGLSEFGVFRHVVKNAAPTAIAIMGLQLGYLLGGSILIETVFAWPGTGFLLNAAIFQRDLPLLQGTILVLAMFFVTLNLLVDVVQTALDPRIQRA
>NC_010511.1|WP_043702384.1|3015612_3017922_-|EAL-domain-containing-protein
MPFYEDVVLGNLRRAAPRAALVALPGEDPAHVLWSGEAFEAWLGRPPQGVAVAALGEGLGHSLGAILRDALAGGQPVRARCNQVSGGMVLSTEILGLPLRDRTGGRYVLLCLLGETSRTNLLKAILRATGQGILALSAVRDEAGGVVDFQVVALNEAAAEMIGGPAALMWQRLSAILPGPVAEATTARLRPIAGASGRLSFEAAYRRADGAVLHLKIEAASLGDHLGLTLTDIGDVKAREESARLLFETNPLPMWVTDEAGRFLAVNDAAIGHYGYASPDFLRMSLRDLAVAGGAGSGEAPARHRRRDGSVIEVAAYSRRIPFEGRSATLTALVDVTERRRAEARITHMAHHDALTDLPNRVLFRQRIVAALEAQARDGRSAGLLCLDLDRFKLVNDTLGHPAGDELLRQAAQRLASCAQDGSVARLGGDEFALLAPADGPEAVMATARRVIAALAQQPFLVAGQAVQVGASVGVALLPADGTDPDVLLRRADMALYAAKAAGRGTAVAFEPAMDEAIQARRILEADLRAALEAGALEVHYQPLHDCRTLRILGCEALLRWRHPARGFVPPGEFVPLAEDLGLIGELGAFVLRAACREAAGWSVPLRVAVNLSPAQFRSPGLALSVTAILAETGLDPRRLDLEITETVLLSEDAANVAILSELRALGVRIAIDDFGTGYASLSYLRAFPFDQIKIDRSFVGRLGEDPQSAAIVRAVTDLGRSLGIVTVGEGVETPRQLEQLRAFGCDVVQGYLLGRPVPAAALRPLLAA
>NC_010511.1|WP_012332558.1|3018137_3019685_-|acetolactate-synthase-large-subunit
MTMNGAESLVRTLVAGGVEVCFTNPGTSEMHFVAALDRVEGMRAVLCLFEGGATGAADGYARMTDRPASTLLHLGPGLGNGIANLHNARRARSPMVNIVGEHATYHRAFDAPLTSDIEGLARPVSAWLRTGLSAREVARDGAAAVAAALTPPGGVATLILPADTAWEEGGGVAPVPAIPARARVPDEAITHAAAALASGEPVLLHLGDRAVRGEGRRIAARIAARTGAQLLAMTSNARIDRGAGSVPIERLPYPVDPARAVLAPFRHIMLVGATLPVAFFAYPGKPSALAAPTCDVFALAAPEQDQIDALERLAEAVGAPAAADLPAPARPVLPGGERLDQDSVGQVLGALIPEGAIICDESITTGRNFFPVTQGAAPHTWLQLSGGAIGLGIPMATGAAVACPDRKVIALQADGSALYTAQSLWTQAREGLDVVTLIWSNRSYAILRAELAHVGANPGRKALDMLTLDDPPIDWPSLARGYGVEGCRVETLPRLVDVLTRALARRGPFLIEVAL
>NC_010511.1|WP_012332559.1|3019925_3020984_+|hypothetical-protein
MRLFQCQFCGNILYYENHTCERCGHRLAYLPETGTLSALEPVGDGSWTPLAAPDRPGLFCTNAEHDACNWLVPPGTRDAFCLACRHNGTIPDISDPGRLLAWRKMESAKHRLFYTLLRWNLPLHTRAEDPEHGLIFNFLADPPADGPKVMTGHDNGVITIALVEADDAERERRRAAMGEPYRTLLGHFRHEVGHHYWDVLVRDAGKLDACRAVFGDDSENYEEALKRHYAEGVPPNWQENFVSAYATTHPWEDFAETWAHYLHIVDTLEMASAFGMQVQPLLDATGTLAARIGFDPYRADSIEQVVSTWLPVTFALNSVNRAMGLNDVYPFVLAPPVIAKLGFIHDLVHRRI
>NC_010511.1|WP_012332560.1|3021111_3022104_+|fumarylacetoacetate-hydrolase-family-protein
MKLASLAHGRDGRLVVVSRDLTRATDAFIVVPTLQQALDEWDRHGPALEALAEQLEHGSVPSFRFHEHACAAPLPRAFARRHAAAWPGHVRLLRQAEGAEAPSDSGTPLRHAASDGFLAPRATLPADPAASLDVSAGLAVITGDVAQGTAPAQAAGAVRLVTLVTEVIRRDRLKPDGLDLDGPLAAGFAASLGPVAVTPDELGPDWQDGMVQRPLCVTRNGALLGRPEAGSDLGSGFGELIAEAARLRPLGAGTIVSAGPVSNRGIDGGPGRSVAEGGAGFASLAEARAAEIVASGWARLPYLAPGDRLRVEVKDRGGHSVFGAIEHEVA
>NC_010511.1|WP_012332561.1|3022180_3022624_+|glyoxalase
MPDPEPLPELAEVLTEGVLRPAIHLDHCVIHVSDWDRATAFYSDVLGAEPVPVGRGFAYRFGGVQLNVHGPGQIGEPRARLPVMPGGSDLCFRWSGPIEEAVAHLERHGVAVELGPVPRNGAAGPGLSVYFRDPDGSLMEFITYPTP
>NC_010511.1|WP_012332562.1|3022900_3024199_+|pilus-assembly-protein-TadG
MRSEGGWVRRGVTRSRRVFAADRSGSIGMMFVVTLVPVLLLVGAAVDFTSYQKARTELDAVADQAVLAAVSAAGMKMSQADAEAAMAKLFTDAAAALPNVSASPRAATAPTTDGVRTASLTYSATIRTGIMRLAGFSTVAFGGTATAASPNPIFTDFYLLLDNSPSMGVAATTADIATMVANTSDQCAFACHDMSAGGNDYYAKAKNLGVKMRIDVVRDATQQLMDTASAKAIAAGQYRMAIYSFGTSCSGIGLNQVSALTANLSTSKTDAGALDLMTVPYQNYNNDQCTDFDGIFARLNSAVPNPGSGASAASPQKVVFFVSDGVADANYPSTCTKPTTNGRCQEPITLANCQALKDRGIRVAVLYTTYLPLPTNGWYNTWIAPFSSQIATNMAACASPDLYWPVSPSEGIADAMKGLFKKVVDSQRRITN
>NC_010511.1|WP_012332563.1|3024230_3024992_-|SDR-family-oxidoreductase
MDLAAGLRGRHVLVTGASSGLGAHFARLCARSGAEVTVAARRRDRLDRLVEALREAGAPRASAVALDVADADSVEAAFAGLARLPDVVVNNAGVAEGGPALDTDLSVFDRVIATNLRGVWAVSVAAARRWRGAARGGVILNVASILGLRVAGGVGPYTVSKAGVVQMTEALALEWARYGIRVNALAPGYIDTDINRDFFATPAGEALVRRIPMRRLGQPEDLDAAFLLLATDASAWMTGVTLPVDGGHLVSGL
>NC_010511.1|WP_043701180.1|3025012_3025459_-|Crp/Fnr-family-transcriptional-regulator
MTLETEVQSLRQVPMFREVDPPRLKLLAFTSERVHFAAGQKFFDQGDAADAAYLILEGEAAVTLDRPIGPIRVAVLGVNALVGEMGILADQPRSATVTAVVPTTALRIDRRVFLELLSQFPQIAIAVMRELAHRLEMTNQQLAQSRSG
>NC_010511.1|WP_043701185.1|3025544_3028439_-|multidrug-ABC-transporter-ATP-binding-protein
MRVPARGGRHRDGVVARSGQERMDGAEALRRNGVAAPVADRATPRAAPMIGTDPEAADAAGGLDRSLFRYIWRHSKRDQILICAVVLASLPLYFASLDLPRRIVNEAIQGHAFEKGNATAHFLVLRLRVPDWFGGERALFDGFEVDRFELLFGLSSLFLLLVLINGAFKYWINVAKGALGERMLRRLRFQLFSLILRFSPESIRQAKASELATIVRDEVEPIGGFIGDAYILPAFLGTQAATAMAFILLQNVWLGLMAAAVVGVQFVVIPRLRRELLRLGRRRQLASRRLAGRVGEVVDGIEAVHANGAEPWERAEIGQRLFGLFDLRLRIYRRKFMVKFLNNLLAQMTPFLFYCIGGYFALKGQLSIGQLVAVIAAYRDLPPPLKELIDWDQQRLDVQVKYEQVVQQFLPDRLLPAEVPGRDTPLVGPLEADDLWVRESQGPLLEGVSLSVTLPLRLGIVSDGSQAASALARVLAHRLAPSRGRITVGGHDLGEWGSLALARRIAYASVEPILFPGSLRENIVYGLQRPPEQVPPPETLEDRRRLAEARRTGNPLASLSGDWIDYAQAGVPDAAALDGVILGWLRRIGMGEEVYRFGLLGQVDPERHPNLASRMIEARGALRARLAAQGMENLVEPFDPERYNSQATVGENLLFGVPTTASLTGRAMAEHPVVRAVLDERGLAEDFVTMGEQIAQTMLEIFQGLPMGHPLFEQFSFLSADELPEYEAILARRTATEASEARHGSSWLARVRRRWLGLERYGGADATRLIALPLAYIEPRHRLGLLDDALRARLVEARAALRAALAEAGEGGVEFYEPDAVCAAAPLRDNLLFGRINQSAADAAAAVTAAITATVEAMNLADAVARVGLDHQVGPAGRFLTGGQRAAISLVRGLVRRPDLLVLDGALGPMGENRARAVLTLLVQHFGREGSLVAVLPNERFASHFDVVLRARGTSVAADARTSG
>NC_010511.1|WP_012332566.1|3028753_3028957_-|hypothetical-protein
MTNPNMVQRRAATQPDTAPAPNCDAVPPVPAPEDSPTPTTDHDPEDSPHAQDLVVTRRAGGLTTRKE

You can click texts colored in the table to view more detailed information

Click the colored protein region to show detailed information

Crispr_ID: NC_010511_17

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_010511_17

3091222-3091326

Orphan

Consensus_repeat	Method
AGCCCGCGCGGCGCCTGAGCGAAGCCGACATCCGCAT	CRISPRCasFinder

1 spacers

The CRISPR arrays of NC_010511_17

>merge|NC_010511|17|3091222-3091326|CRISPRCasFinder
AGCCCGCGCGGCGCCTGAGCGAAGCCGACATCCGCATTGCGAAGCAATCCGTCGGATGTCGTATCCCAAGCCCGCGCGGCGCCTGAGCGACGCCGACATCCGCAT

>NC_010511|17|17|3091222-3091326|CRISPRCasFinder
AGCCCGCGCGGCGCCTGAGCGAAGCCGACATCCGCAT	TGCGAAGCAATCCGTCGGATGTCGTATCCCA
AGCCCGCGCGGCGCCTGAGCGACGCCGACATCCGCAT

Protein	Signature genes	Signature genes Name	Protein_function
NC_010511.1\|WP_150108830.1\|3079702_3080500_-\|FkbM-family-methyltransferase	unknown	unknown	gnl\|CDD\|273628
NC_010511.1\|WP_012332622.1\|3085229_3086750_+\|aldehyde-dehydrogenase-family-protein	unknown	unknown	gnl\|CDD\|143434
NC_010511.1\|WP_085984491.1\|3099795_3100633_+\|IS5-family-transposase	unknown	unknown	gnl\|CDD\|379129
NC_010511.1\|WP_012332632.1\|3097908_3099441_+\|transcriptional-regulator	unknown	unknown	gnl\|CDD\|227903
NC_010511.1\|WP_012332620.1\|3083478_3084456_+\|AraC-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|378976
NC_010511.1\|WP_043702390.1\|3102775_3104050_-\|response-regulator	unknown	unknown	gnl\|CDD\|143636
NC_010511.1\|WP_018260759.1\|3080780_3081071_+\|hypothetical-protein	unknown	unknown	unknown
NC_010511.1\|WP_012332626.1\|3092751_3092964_+\|hypothetical-protein	unknown	unknown	unknown
NC_010511.1\|WP_012332634.1\|3102143_3102767_+\|DsbA-family-oxidoreductase	unknown	unknown	gnl\|CDD\|239322
NC_010511.1\|WP_012332628.1\|3094044_3094611_-\|c-type-cytochrome	unknown	unknown	gnl\|CDD\|225418
NC_010511.1\|WP_012332621.1\|3084667_3084850_-\|hypothetical-protein	unknown	unknown	unknown
NC_010511.1\|WP_012332629.1\|3094667_3095717_-\|sorbosone-dehydrogenase-family-protein	unknown	unknown	gnl\|CDD\|225044
NC_010511.1\|WP_012332630.1\|3096829_3097012_-\|hypothetical-protein	unknown	unknown	unknown
NC_010511.1\|WP_012332625.1\|3089624_3091025_+\|metal-ABC-transporter-permease	unknown	unknown	gnl\|CDD\|224033
NC_010511.1\|WP_012332633.1\|3100704_3101829_+\|IS630-family-transposase	unknown	unknown	gnl\|CDD\|315923
NC_010511.1\|WP_150108646.1\|3083097_3083352_-\|hypothetical-protein	unknown	unknown	unknown
NC_010511.1\|WP_012332619.1\|3081661_3082501_+\|class-I-SAM-dependent-methyltransferase	unknown	unknown	gnl\|CDD\|379312
NC_010511.1\|WP_168169154.1\|3088698_3089628_+\|zinc-ABC-transporter-substrate-binding-protein	unknown	unknown	gnl\|CDD\|376518
NC_010511.1\|WP_012332631.1\|3097318_3097780_-\|cupin-domain-containing-protein	unknown	unknown	gnl\|CDD\|369571
NC_010511.1\|WP_168169153.1\|3087418_3088657_+\|amidase	unknown	unknown	gnl\|CDD\|225279

Protein	Function_ID	Function_description	E-value
NC_010511.1\|WP_150108830.1\|3079702_3080500_-\|FkbM-family-methyltransferase	gnl\|CDD\|273628	TIGR01444, 2-O-methyltransferase_NoeI, methyltransferase, FkbM family. Members of this family are characterized by two well-conserved short regions separated by a variable in both sequence and length. The first of the two regions is found in a large number of proteins outside this subfamily, a number of which have been characterized as methyltransferases. One member of the present family, FkbM, was shown to be required for a specific methylation in the biosynthesis of the immunosuppressant FK506 in Streptomyces strain MA6548.	4.48175e-32
NC_010511.1\|WP_012332622.1\|3085229_3086750_+\|aldehyde-dehydrogenase-family-protein	gnl\|CDD\|143434	cd07116, ALDH_ACDHII-AcoD, Ralstonia eutrophus NAD+-dependent acetaldehyde dehydrogenase II-like. Included in this CD is the NAD+-dependent, acetaldehyde dehydrogenase II (AcDHII, AcoD, EC=1.2.1.3) from Ralstonia (Alcaligenes) eutrophus H16 involved in the catabolism of acetoin and ethanol, and similar proteins, such as, the dimeric dihydrolipoamide dehydrogenase of the acetoin dehydrogenase enzyme system of Klebsiella pneumonia. Also included are sequences similar to the NAD+-dependent chloroacetaldehyde dehydrogenases (AldA and AldB) of Xanthobacter autotrophicus GJ10 which are involved in the degradation of 1,2-dichloroethane. These proteins apparently require RpoN factors for expression.	0
NC_010511.1\|WP_085984491.1\|3099795_3100633_+\|IS5-family-transposase	gnl\|CDD\|379129	pfam13340, DUF4096, Putative transposase of IS4/5 family (DUF4096).	1.78337e-29
NC_010511.1\|WP_012332632.1\|3097908_3099441_+\|transcriptional-regulator	gnl\|CDD\|227903	COG5616, COG5616, Predicted integral membrane protein [Function unknown].	1.7278e-45
NC_010511.1\|WP_012332620.1\|3083478_3084456_+\|AraC-family-transcriptional-regulator	gnl\|CDD\|378976	pfam12852, Cupin_6, Cupin. This is a family of bacterial and eukaryotic proteins that belong to the Cupin superfamily. Some of the proteins in this family are annotated as being members of the AraC family of transcription factors, in which case this domain corresponds to the ligand binding domain.	5.3016e-47
NC_010511.1\|WP_043702390.1\|3102775_3104050_-\|response-regulator	gnl\|CDD\|143636	cd07302, CHD, cyclase homology domain. Catalytic domains of the mononucleotidyl cyclases (MNC's), also called cyclase homology domains (CHDs), are part of the class III nucleotidyl cyclases. This class includes eukaryotic and prokaryotic adenylate cyclases (AC's) and guanylate cyclases (GC's). They seem to share a common catalytic mechanism in their requirement for two magnesium ions to bind the polyphosphate moiety of the nucleotide.	1.75676e-52
NC_010511.1\|WP_012332631.1\|3097318_3097780_-\|cupin-domain-containing-protein	gnl\|CDD\|369571	pfam07883, Cupin_2, Cupin domain. This family represents the conserved barrel domain of the 'cupin' superfamily ('cupa' is the Latin term for a small barrel).	1.4435e-17
NC_010511.1\|WP_012332634.1\|3102143_3102767_+\|DsbA-family-oxidoreductase	gnl\|CDD\|239322	cd03024, DsbA_FrnE, DsbA family, FrnE subfamily; FrnE is a DsbA-like protein containing a CXXC motif. It is presumed to be a thiol oxidoreductase involved in polyketide biosynthesis, specifically in the production of the aromatic antibiotics frenolicin and nanaomycins.	1.66361e-78
NC_010511.1\|WP_012332628.1\|3094044_3094611_-\|c-type-cytochrome	gnl\|CDD\|225418	COG2863, COG2863, Cytochrome c553 [Energy production and conversion].	2.71992e-18
NC_010511.1\|WP_012332629.1\|3094667_3095717_-\|sorbosone-dehydrogenase-family-protein	gnl\|CDD\|225044	COG2133, COG2133, Glucose/sorbosone dehydrogenases [Carbohydrate transport and metabolism].	2.31138e-69
NC_010511.1\|WP_012332625.1\|3089624_3091025_+\|metal-ABC-transporter-permease	gnl\|CDD\|224033	COG1108, ZnuB, ABC-type Mn2+/Zn2+ transport systems, permease components [Inorganic ion transport and metabolism].	4.03875e-25
NC_010511.1\|WP_012332633.1\|3100704_3101829_+\|IS630-family-transposase	gnl\|CDD\|315923	pfam13358, DDE_3, DDE superfamily endonuclease. This family of proteins are related to pfam00665 and are probably endonucleases of the DDE superfamily. Transposase proteins are necessary for efficient DNA transposition. This domain is a member of the DDE superfamily, which contain three carboxylate residues that are believed to be responsible for coordinating metal ions needed for catalysis. The catalytic activity of this enzyme involves DNA cleavage at a specific site followed by a strand transfer reaction.	2.56459e-17
NC_010511.1\|WP_012332619.1\|3081661_3082501_+\|class-I-SAM-dependent-methyltransferase	gnl\|CDD\|379312	pfam13649, Methyltransf_25, Methyltransferase domain. This family appears to be a methyltransferase domain.	4.09585e-24
NC_010511.1\|WP_168169154.1\|3088698_3089628_+\|zinc-ABC-transporter-substrate-binding-protein	gnl\|CDD\|376518	pfam01297, ZnuA, Zinc-uptake complex component A periplasmic. ZnuA includes periplasmic solute binding proteins such as TroA that interacts with an ATP-binding cassette transport system in Treponema pallidum. ZnuA is part of the bacterial zinc-uptake complex ZnuABC, whose components are the following families, ZinT, pfam09223, pfam00950, pfam00005, all of which are regulated by the transcription-regulator family FUR, pfam01475. ZinT acts as a Zn2+-buffering protein that delivers Zn2+ to ZnuA (TroA), a high-affinity zinc-uptake protein. In Gram-negative bacteria the ZnuABC transporter system ensures an adequate import of zinc in Zn2+-poor environments, such as those encountered by pathogens within the infected host.	3.08834e-67
NC_010511.1\|WP_168169153.1\|3087418_3088657_+\|amidase	gnl\|CDD\|225279	COG2421, COG2421, Predicted acetamidase/formamidase [Energy production and conversion].	2.06966e-75

>NC_010511.1|WP_012332625.1|3089624_3091025_+|metal-ABC-transporter-permease
MIADLAALLAVPLAVTAIFIGVHTYLGLHVLRRRVVFADLALAQLSALGATLAVALGHAPSDLAAFAYAMLFAFSGAVALTASRSVSWAVSQEALVGVLYVAASAATVLVIDRAPQGAEHVKRMLVGTLLDARPEQLAKIVPLYSAVALLHWAARRPLLDASENRLTGARGVLWDFVFYASFGAIVTSSVAVAGVLLVFSFLIIPAVTGTLFAADRIGLALLIGWCVGLTASLGGFASSLAFDLPTGACVVLTLFAALGLAALARFLWIGDPNETTQRRARARQASSIGLLSLMLAGSLWSFIRPGADQPLLAALNRIGLRPERFMDDAEAARYAEAAAMERRYRAEVEALSNQERQSRWRGAGLTDDEVRRIASYQQTYNEMARGERFVQDHLLARAHARERWQVSLPLAVVSAAALLVLVFRTRVMRRPTRTPSDGAGEPLDDATRKPPLTGSLNAFRWSKKSL
>NC_010511.1|WP_168169154.1|3088698_3089628_+|zinc-ABC-transporter-substrate-binding-protein
MGALALLVLPLLLCPAAVRAAQGGPVRVVATTPDLKSLVEAVGGDAVVAASLVPPGADPEAYEVRPGDLLGLRGADLVVRVGLGYDHWLDPLLARHADPKLMRGGAGQVDASAGIPLLEVLGSSVEAGATGGHAHGLANPHYWLDPANAETITAGIADGLARVAPGRAALVAENRGRFLAGLARRLASWQARLAPYAGAPVVAYHNDWPYFARRFRLNVVAVVEPKEGIAPSPAQLARVAGLMREQGVRVVLAKPNAPRGPAEAVAARTGARVVVLAGSVGELSGTGDYLGLFEVDVDVLHDAFEAGGR
>NC_010511.1|WP_168169153.1|3087418_3088657_+|amidase
MPFVYGPLQQQGMNAPSHHAKGKVHLLPATPATTQWGWFDNSQPPVLRIQSGDTVAMETMMHAHNQVVPGITIDQVKKTRTDYPGRGPHTLTGPIYVEGAEPGDVLRVHINKIVPRAYATNFNLPGLFGEFPKEFPEGQIRFFYLDLDRKTMEFAPGIEIPLRPFPGTTAVARAEPGRYSSVPPGRFAGNLDIRELTEGATLYIPVFVQGALLWSGDSHAGQGNGEVNLCAIETAFKELNVTVEVIKGATLDWPRIETPTDWITVGYDQDLNKALDLLRDQTTRFIIERDKVSQAQAEQSMLENWNCPISEVVNVVKGTYCMLPKDGRKPTQLPRAETPEVFVTTGRDADLNRAMDTASMAMINMLVERKELSRLDAYALASMAMDCRIAAPRDAEKEVSCMVPKSLWVNQR
>NC_010511.1|WP_012332622.1|3085229_3086750_+|aldehyde-dehydrogenase-family-protein
MNKPEFLRGQTASPFAARYDNFIGGQWVAPAAGRYFENTSPLTGRLICEVARSDAQDIERALDAAHAAKDAWARTAPAERARILTRMADRMEDNLDLLALAETWDNGKPIRETTHADIPLAIDHFRYFAGCVRAQEGSLSEIDHDTVAYHFHEPLGVVGQIIPWNFPILMAVWKLAPALAAGNCVVLKPAEQTPASVLVLAEIIGDLLPAGVLNIVNGFGLEAGKPLASSPRIAKIAFTGETSTGRLIMQYASQNLIPVTLELGGKSPNIFFEDVMARDDAFLDKVLEGFAMFALNQGEVCTCPSRALVQESIYERFIEKAVARVEAIRQGSPLDPATMIGAQASGEQLAKILSYIDIGRQEGAQLLTGGERAVLAGEFAEGFYVKPTVFRGHNRMRIFQEEIFGPVLSVTTFKDEAEALAIANDTLYGLGAGVWTRDGTRAYRFGREIQAGRVWTNCYHAYPAHAAFGGYKQSGIGRETHKMMLDHYQQTKNLLVSYSPKALGFF
>NC_010511.1|WP_012332621.1|3084667_3084850_-|hypothetical-protein
MKLYEDFFHPDAQVEIAGDRFVVTLPDGRSLSFKVEGHACHNPNVKCPPSFDIRDQLDEE
>NC_010511.1|WP_012332620.1|3083478_3084456_+|AraC-family-transcriptional-regulator
MTADVLSDVLSAVRLTGSVFFDVTATAPWVAEAPPSAQIAGAVLPGAQHAIEYHVLTRGSCWISIVDGAPFEPVRLHEGDIAIIPHGEPHAVSSAPGMRAGPDLDAHRRPNEVGGLPIRLRAGAGGADDAHVICGFFSCDVRPFNPLLDALPRFVRVGRGASPATDGLLNQFVLLLSHETKHRRPGAQSVLNRLSELMLIEAVRTYMDQLDPGHIGWLSGLRDPLVGHALGLLHAEPARAWTLEDLAAACGASRSALAGRFTQLTGYPPIQYLTRWRMQLAAKRLSEGGAKVAAVAQDVGYDSEAAFSRAFKKFSGRSPSEWRSG
>NC_010511.1|WP_150108646.1|3083097_3083352_-|hypothetical-protein
MGKSLHGQQPRSPCEPKLGRIAGALHIRGALRRRCPKSSARSSVKSSAVLAKSSVLRLVVSSDPEQLRGHRIAPSIQHRRGRRE
>NC_010511.1|WP_012332619.1|3081661_3082501_+|class-I-SAM-dependent-methyltransferase
MSTVIDCRPTAAAPDLAAIKARQQLAWSSGDYAVVGTTLQIVGEQLAEAMDLRAGQDVLDVAAGNGNFTLAAARRWCNVTSTDYVEPLLERGRLRAEAEGVAVTFRKADAENLPFADRSFDAVASTFGAMFSPDQGRTAGEMLRVCRPGGRIGLANWTPDGFIGQMFKIIGKHLPPPPGLKSPALWGTPEWIDTSFAAEASSLIAQSRHFTFRYRSVQHFLGTFRTFYGPMLKAFEALGATARIALAQDLTGLIGHFNKSGDATVVVPSEYLEVVVTRR
>NC_010511.1|WP_018260759.1|3080780_3081071_+|hypothetical-protein
MQWPALVVIVRAASGICASRQGSDRLARLAEKDGADTPLERVLEGVAHDCPYPPPDRVRGNAYVARRHAGFPDLTGPPKPPVLPPARWVGPGHVRQ
>NC_010511.1|WP_150108830.1|3079702_3080500_-|FkbM-family-methyltransferase
MTMSAGHRMLVDRRSTTERGPFYLRTYDQQKIELLRRFIEPGTAVLDIGANVGFFTVPLGIFVRDQRRFGRVFAFEPVPGNRDRLQENILINALDETVTIIPAALSSKPGTVEISLREDFQNGSRTGNAAIVISTEDNLFETTRIVTMRLDDYVAHEIALPISVIKIDTEGHEDEVLAGGNETIARNRPVILMEVEPNYYERKGVDFYERVRAVLPPDYRFLAVGLHRQSVLRPLGTRLSFTEIRDRPSFMRPQDVLLLPPGRHV
>NC_010511.1|WP_012332626.1|3092751_3092964_+|hypothetical-protein
MDEDRFNIELRKFLKEVGVTSQREIERVAREGLVSGNTLKLRMTLTAENAPLQHVVERTIALDGETDPAS
>NC_010511.1|WP_012332628.1|3094044_3094611_-|c-type-cytochrome
MRLFPFALALLASTASPALAEPVGERLAPCLGCHGESGRSETPGVPSLGGQPADYLVTQLYQFRESQRVAPPMNEMAAGLSDDDLRSFAEELSRLPAPSPGETALDSTLAERARALVGRHQCNSCHGADLAGRDAIPRIRGQREDYLLKALAGYKSNARPGYDPAMNEVAQGLSEADIEVLAAFLSRS
>NC_010511.1|WP_012332629.1|3094667_3095717_-|sorbosone-dehydrogenase-family-protein
MPTPAAKLPVDRLKVPAGFKVEVFASGVANARSLRQGDKGTVFAGTRLLDRVYAIRDRDGKREVKVIASKLHRPNGLAFHKGALYVAELSKVWRFDDIEAHLDEPPKPVLVYDDLPKDEAHGWKFIAIGPDEKLYVPVGSPGNILMPPDTHAQIRRMNLDGSGVEVVARGVRNTVGFDWNPATKQLWFSDNGRDWVSEDIPEDELNVLTEPGKQHFGFPFCHQGTFTDPEYGWGRSCAEFTAPAALLGPHTAALGLRFYTGTQFPEAYRNAIFVARHGSWNRTKKLGGDVVAVKLGPDGKVASIEPFLTGFIEDNRYLGRPVDVLVAQDGALLVSDDYNGAIYRISYQP
>NC_010511.1|WP_012332630.1|3096829_3097012_-|hypothetical-protein
MKLYEDFFHPDAQVEIVGDRFVVTLPDSRSLSFKAEGHKCHNRNARCPPCFDIRDQLDEE
>NC_010511.1|WP_012332631.1|3097318_3097780_-|cupin-domain-containing-protein
MHAVPVIHLPDEAPRLTVAGHPMAVLVTARESRYACMFDWVVPPRFSTGLHVHRVQEETFYVLDGACEWQVEDRVVTARRGAYLFIPPGVPHDIRNPSAVPARLLMTVSPPGHEAYFEELAGLAGSGPPDPRTLAALRRRFDTDQLSSLTVTG
>NC_010511.1|WP_012332632.1|3097908_3099441_+|transcriptional-regulator
MALWLDFGPFRLDTEMKLLLRDGAPVALGPRAVAVLQALVARAGAPVSKEELFRVAWPDLAVEDSNLTVQIAALRRALAGSEDGARWIETLPRRGYRYVGPVGAAPSMPPVMPRFPDRPSVAVLPLRNLSGDPAEDYFGDGMAEDITAGLSRIKWLFVTARSSGAVYRGREIDPCEAGRALGARYLLLGSLRKETARIRVALRLVESEAGGVVWAEAYDRPLEGVFALQDDIAMSVVGAIEPNLRQAEAERVRRLRPESLDAYDLVLRAQSDVFTGMPAESSRALGLLGRALELEPRYGLAHAFAAMCHHNLFLRAGLSEVDRAASIRHAEKAIAHGRDDALALTFAGFSLAMDAHDRRAGSAAFEAALAVSPSSATTYILGGVVHGWAGDAERAITWGERALRLSPFDPWAFAAYHALALGHLVAGRAEAAAAAAYKGVHANPVHSISHMILAATLARLGSLDTARAAAARVMALQPVFRFSRQLAGVDCAPDLAAALGEALRACGLPE
>NC_010511.1|WP_085984491.1|3099795_3100633_+|IS5-family-transposase
MRRFELTDAQWEQIAPLLPPQKPRTGRPAEDHRQVLNGMLWILRTGAPWEDLPARYGPVGTVSSRFYGWRKAGVFDRVLQRLQAQADARGDLDWDLHVVDATVVRAHPHAAGARRSGAIGGEGTVEGVGEALGRSQGGFSTKLHLRAEGGGKPMAAVLTAGERHEQFALDALMDKGAVRRRGRGRPRLRPRRAAGDRGYSSPPARRRLKQRRVEPVIPTRKDQPRQPDFDKAAYRERNRVERLINRLKQYRRIATRYETRAANDLAMVTLGMTMLWLS
>NC_010511.1|WP_012332633.1|3100704_3101829_+|IS630-family-transposase
MAYRVPTSLDLSAEERAELESWARRRKTAQGLALRARIVLLAADGLSNTTIAAELATGKHTVGKWRERFASQRTDGLLDEPRSGAPRRIGDDQVAELIDRTLCERPPGASHWSRRSMAKASGVSSTTVGRVWRAFGLQPHRSETFKLSTDPLFAEKVRDIVGLYLAPPARALVLCVDEKSQVQALDRTQPLLPLRPGQAERRTHDYARHGTTSLFAALDVKAGTVIGQCYPRHRASEFRRFLDEIEATVPADLDVHLVLDTSATHKTKLIRDWLAQRPRYHVHFTPTSASWINQVERWFGLLTDRAIRRGVHCSVEELERDIRAFIQATNADPKPFRWVKSADAILASVKRFCLRTIDPETDDAPLPQTSGAGH
>NC_010511.1|WP_012332634.1|3102143_3102767_+|DsbA-family-oxidoreductase
MPLTISVFSDVICPWCYVGKRRLERALDQLGMRETTAVEWLPFELNPDMPVEGMERAHYRARKFGVERSAQLDAQMAELGRQEGIHFAFDQMLRTPNTRRAHMLIAFATQHGRAGAVVDGLFRAYFEAGRDVGDPDELLNVGVAAGLDRALVDEALNSEQLAQFVEHVEQQAAHMQVTGVPFFIVHRKWAVSGAQSTEQWIEILSAA
>NC_010511.1|WP_043702390.1|3102775_3104050_-|response-regulator
MAEGSKPVDTKVLVVDDESDLEALIVQKFRRRIREGAIRFLFARDGLEALAVIAEHPDVDLVVSDINMPRMDGLTLLAKLQEADEKLSTVIVSAYGDMANIRTAMNRGAFDFLTKPIDFSDFETTVDRTVLHVRTLREARRRQSAAERAHASLSRYFSPNLAERLAADASALAGGHRRDVASLFTDIAGFTTLVESLDPALLAELLNGYLAEMTGLVFSHDGTVAKIVGDAIHVLFGAPGEQPDHATRAVSCALALDAAAEAFRARWAERGVVLGSTRIGVHAGPAIVGNFGGGRFFDYTAYGDTINITARLEAANKVLGTRLCVSAAVAERAEGFRGRPIGDLVLRGRTEALRTFEPLSEAAFADPGTARYGEAFEKLAAGDPGALPAFASLVGLNADDHLASFHLRRLLNGVSGTRIDLRTA

You can click texts colored in the table to view more detailed information

Click the colored protein region to show detailed information

Crispr_ID: NC_010511_18

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_010511_18

3272004-3272098

Orphan

Consensus_repeat	Method
TCGGCGTCGCTCAAACGCCGCGCGGGC	CRISPRCasFinder

1 spacers

The CRISPR arrays of NC_010511_18

>merge|NC_010511|18|3272004-3272098|CRISPRCasFinder
TCGGCGTCGCTCAAACGCCGCGCGGGCGTGCCAGACGACATCCGACGGATTGCTTCGCAATGCGGATGTCGGCTTCGCTCAAACGCCGCGCGGGC

>NC_010511|18|18|3272004-3272098|CRISPRCasFinder
TCGGCGTCGCTCAAACGCCGCGCGGGC	GTGCCAGACGACATCCGACGGATTGCTTCGCAATGCGGATG
TCGGCTTCGCTCAAACGCCGCGCGGGC

Protein	Signature genes	Signature genes Name	Protein_function
NC_010511.1\|WP_012332763.1\|3271694_3271952_+\|hypothetical-protein	unknown	unknown	unknown
NC_010511.1\|WP_012332770.1\|3280712_3282992_+\|LPS-biosynthesis-protein	unknown	unknown	gnl\|CDD\|225747
NC_010511.1\|WP_012332757.1\|3261720_3264051_+\|RNA-binding-transcriptional-accessory-protein	unknown	unknown	gnl\|CDD\|225094
NC_010511.1\|WP_012332756.1\|3260719_3261655_+\|DMT-family-transporter	unknown	unknown	gnl\|CDD\|223769
NC_010511.1\|WP_012332760.1\|3265679_3268682_+\|PAS-domain-containing-sensor-histidine-kinase	unknown	unknown	gnl\|CDD\|223715
NC_010511.1\|WP_012332767.1\|3276793_3278314_-\|undecaprenyl-phosphate-glucose-phosphotransferase	unknown	unknown	gnl\|CDD\|274396
NC_010511.1\|WP_012332761.1\|3268778_3270095_+\|ABC-transporter-substrate-binding-protein	unknown	unknown	gnl\|CDD\|380557
NC_010511.1\|WP_012332766.1\|3274962_3276654_+\|cation-acetate-symporter	unknown	unknown	gnl\|CDD\|236495
NC_010511.1\|WP_012332768.1\|3278415_3279822_-\|glycosyltransferase-family-4-protein	unknown	unknown	gnl\|CDD\|340831
NC_010511.1\|WP_012332755.1\|3260146_3260371_+\|YbdD/YjiX-family-protein	unknown	unknown	gnl\|CDD\|377308
NC_010511.1\|WP_012332769.1\|3279964_3280537_-\|polysaccharide-export-protein	unknown	unknown	gnl\|CDD\|224512
NC_010511.1\|WP_012332772.1\|3284044_3284383_-\|cupin-domain-containing-protein	unknown	unknown	gnl\|CDD\|380366
NC_010511.1\|WP_012332762.1\|3270289_3271630_+\|MFS-transporter	unknown	unknown	gnl\|CDD\|182433
NC_010511.1\|WP_012332758.1\|3264399_3264687_-\|hypothetical-protein	unknown	unknown	unknown
NC_010511.1\|WP_012332773.1\|3284435_3284810_-\|PH-domain-containing-protein	unknown	unknown	gnl\|CDD\|377953
NC_010511.1\|WP_012332759.1\|3264997_3265441_-\|phasin	unknown	unknown	gnl\|CDD\|131040
NC_010511.1\|WP_012332765.1\|3274657_3274966_+\|DUF485-domain-containing-protein	unknown	unknown	gnl\|CDD\|377315
NC_010511.1\|WP_012332771.1\|3283208_3283715_+\|L,D-transpeptidase	unknown	unknown	gnl\|CDD\|224294
NC_010511.1\|WP_012332754.1\|3258075_3260139_+\|carbon-starvation-protein-A	unknown	unknown	gnl\|CDD\|184976
NC_010511.1\|WP_012332764.1\|3272385_3274335_+\|acetate--CoA-ligase	unknown	unknown	gnl\|CDD\|234677

Protein	Function_ID	Function_description	E-value
NC_010511.1\|WP_012332770.1\|3280712_3282992_+\|LPS-biosynthesis-protein	gnl\|CDD\|225747	COG3206, GumC, Uncharacterized protein involved in exopolysaccharide biosynthesis [Cell envelope biogenesis, outer membrane].	6.80679e-73
NC_010511.1\|WP_012332757.1\|3261720_3264051_+\|RNA-binding-transcriptional-accessory-protein	gnl\|CDD\|225094	COG2183, Tex, Transcriptional accessory protein [Transcription].	0
NC_010511.1\|WP_012332756.1\|3260719_3261655_+\|DMT-family-transporter	gnl\|CDD\|223769	COG0697, RhaT, Permeases of the drug/metabolite transporter (DMT) superfamily [Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only].	2.57479e-14
NC_010511.1\|WP_012332760.1\|3265679_3268682_+\|PAS-domain-containing-sensor-histidine-kinase	gnl\|CDD\|223715	COG0642, BaeS, Signal transduction histidine kinase [Signal transduction mechanisms].	5.45401e-49
NC_010511.1\|WP_012332761.1\|3268778_3270095_+\|ABC-transporter-substrate-binding-protein	gnl\|CDD\|380557	cd06334, PBP1_ABC_ligand_binding-like, type 1 periplasmic ligand-binding domain of uncharacterized ABC (ATPase Binding Cassette)-type active transport systems predicted to be involved in transport of amino acids, peptides, or inorganic ions. This subgroup includes the type 1 periplasmic ligand-binding domain of uncharacterized ABC (ATPase Binding Cassette)-type active transport systems that are predicted to be involved in transport of amino acids, peptides, or inorganic ions. Members of this group are sequence-similar to members of the family of ABC-type hydrophobic amino acid transporters, such as leucine-isoleucine-valine binding protein (LIVBP); however their ligand specificity has not been determined experimentally.	2.75819e-80
NC_010511.1\|WP_012332766.1\|3274962_3276654_+\|cation-acetate-symporter	gnl\|CDD\|236495	PRK09395, actP, cation/acetate symporter ActP.	0
NC_010511.1\|WP_012332768.1\|3278415_3279822_-\|glycosyltransferase-family-4-protein	gnl\|CDD\|340831	cd03801, GT4_PimA-like, phosphatidyl-myo-inositol mannosyltransferase. This family is most closely related to the GT4 family of glycosyltransferases and named after PimA in Propionibacterium freudenreichii, which is involved in the biosynthesis of phosphatidyl-myo-inositol mannosides (PIM) which are early precursors in the biosynthesis of lipomannans (LM) and lipoarabinomannans (LAM), and catalyzes the addition of a mannosyl residue from GDP-D-mannose (GDP-Man) to the position 2 of the carrier lipid phosphatidyl-myo-inositol (PI) to generate a phosphatidyl-myo-inositol bearing an alpha-1,2-linked mannose residue (PIM1). Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate residue. This group of glycosyltransferases is most closely related to the previously defined glycosyltransferase family 1 (GT1). The members of this family may transfer UDP, ADP, GDP, or CMP linked sugars. The diverse enzymatic activities among members of this family reflect a wide range of biological functions. The protein structure available for this family has the GTB topology, one of the two protein topologies observed for nucleotide-sugar-dependent glycosyltransferases. GTB proteins have distinct N- and C- terminal domains each containing a typical Rossmann fold. The two domains have high structural homology despite minimal sequence homology. The large cleft that separates the two domains includes the catalytic center and permits a high degree of flexibility. The members of this family are found mainly in certain bacteria and archaea.	1.51136e-42
NC_010511.1\|WP_012332755.1\|3260146_3260371_+\|YbdD/YjiX-family-protein	gnl\|CDD\|377308	pfam04328, Sel_put, Selenoprotein, putative. This entry includes a group of putative selenoproteins from Proteobacteria, Actinobacteria and Firmicutes. The invariant cysteine at the C-terminus is encoded by a TGA Sec codon in some Epsilonproteobacteria, suggesting a redox activity for the protein.	2.62053e-21
NC_010511.1\|WP_012332769.1\|3279964_3280537_-\|polysaccharide-export-protein	gnl\|CDD\|224512	COG1596, Wza, Periplasmic protein involved in polysaccharide export, contains SLBB domain of b-grasp fold [Cell wall/membrane/envelope biogenesis].	6.54384e-28
NC_010511.1\|WP_012332772.1\|3284044_3284383_-\|cupin-domain-containing-protein	gnl\|CDD\|380366	cd02238, cupin_KdgF, pectin degradation protein KdgF and related proteins, cupin domain. This family includes bacterial and archaeal pectin degradation protein KdgF that catalyzes the linearization of unsaturated uronates from both pectin and alginate, which are polysaccharides found in the cell walls of plants and brown algae, respectively, and represent an important source of carbon. These polysaccharides, mostly consisting of chains of uronates, can be metabolized by bacteria through a pathway of enzymatic steps to the key metabolite 2-keto-3-deoxygluconate (KDG). Pectin degradation is used by many plant-pathogenic bacteria during infection, and also, pectin and alginate can both represent abundant sources of carbohydrate for the production of biofuels. These proteins belong to the cupin superfamily with a conserved "jelly roll-like" beta-barrel fold.	1.41181e-11
NC_010511.1\|WP_012332762.1\|3270289_3271630_+\|MFS-transporter	gnl\|CDD\|182433	PRK10406, PRK10406, alpha-ketoglutarate transporter; Provisional.	0
NC_010511.1\|WP_012332767.1\|3276793_3278314_-\|undecaprenyl-phosphate-glucose-phosphotransferase	gnl\|CDD\|274396	TIGR03023, Sugar_transferase., Undecaprenyl-phosphate glucose phosphotransferase. This family of proteins encompasses the E. coli WcaJ protein involved in colanic acid biosynthesis, the Methylobacillus EpsB protein involved in methanolan biosynthesis, as well as the GumD protein involved in the biosynthesis of xanthan. All of these are closely related to the well-characterized WbaP (formerly RfbP) protein, which is the first enzyme in O-antigen biosynthesis in Salmonella typhimurium. The enzyme transfers galactose from UDP-galactose (NOTE: not glucose) to a polyprenyl carrier (utilizing the highly conserved C-terminal sugar transferase domain, pfam02397) a reaction which takes place at the cytoplasmic face of the inner membrane. The N-terminal hydrophobic domain is then believed to facilitate the "flippase" function of transferring the liposaccharide unit from the cytoplasmic face to the periplasmic face of the inner membrane. Most of these genes are found within large operons dedicated to the production of complex exopolysaccharides such as the enterobacterial O-antigen. Colanic acid biosynthesis utilizes a glucose-undecaprenyl carrier, knockout of EpsB abolishes incorporation of UDP-glucose into the lipid phase, and the C-terminal portion of GumD has been shown to be responsible for the glucosyl-1-transferase activity.	3.37242e-180
NC_010511.1\|WP_012332773.1\|3284435_3284810_-\|PH-domain-containing-protein	gnl\|CDD\|377953	pfam08000, bPH_1, Bacterial PH domain. This family contains many bacterial hypothetical proteins. The structures of Structure 3hsa and Structure 3dcx show similarities to the PH or pleckstrin homology domain. First evidence of PH-like domains in bacteria suggests role in cell envelope stress response.	2.58414e-57
NC_010511.1\|WP_012332759.1\|3264997_3265441_-\|phasin	gnl\|CDD\|131040	TIGR01985, kDa_protein, phasin. This model represents a family of granule-associate proteins (phasins) which are part of the polyhydroxyalkanoate synthesis machinery. This family is based on a pair of characterized genes from Methylobacterium extorquens. Members of the seed for this model all contain the rest of the components believed to be essential for this system (see the "polyhydroxyalkanoic acid synthesis" property in the GenPropDB). Members of this family score below trusted to another phasin model, TIGR01841 and together may represent a subfamily or broader equivalog.	7.65397e-26
NC_010511.1\|WP_012332765.1\|3274657_3274966_+\|DUF485-domain-containing-protein	gnl\|CDD\|377315	pfam04341, DUF485, Protein of unknown function, DUF485. This family includes several putative integral membrane proteins.	7.24153e-35
NC_010511.1\|WP_012332771.1\|3283208_3283715_+\|L,D-transpeptidase	gnl\|CDD\|224294	COG1376, ErfK, Uncharacterized protein conserved in bacteria [Function unknown].	1.41442e-32
NC_010511.1\|WP_012332754.1\|3258075_3260139_+\|carbon-starvation-protein-A	gnl\|CDD\|184976	PRK15015, PRK15015, carbon starvation protein CstA.	0
NC_010511.1\|WP_012332764.1\|3272385_3274335_+\|acetate--CoA-ligase	gnl\|CDD\|234677	PRK00174, PRK00174, acetyl-CoA synthetase; Provisional.	0

>NC_010511.1|WP_012332763.1|3271694_3271952_+|hypothetical-protein
MRLPRLLALGLLAATLGAGPLAAQNADPGAAPAEPGSTGTVNRNVMATGQTKPPGRAAAPREANQPDRVKELNRKVDTGICIGCD
>NC_010511.1|WP_012332762.1|3270289_3271630_+|MFS-transporter
MTTTFRAAPDALASQNPTIAAFDTRARIRAIIGSSSGNLVEWYDFYAYAFTAIYFKDAFFPGADPTVQLINTAAVFAIGFLMRPIGGWLFGRIADRLGRKNSMLISVLMMCLGSLIIAVLPTYGQIGLLAPVLLLLARMAQGLSVGGEYGTSATYMSEVALKGRRGFYGSFQYVTLIGGQLLASLVVVLVTLGLSDREMSAWGWRIPFLIGALAAVVALYLRRSLHETSTAETRGAQEAGSVRALWQHHRRAFLTVLGYTAGGSLIFYTFTTYMQKYLVNTAHMDKKTANYVMTAVLFTYMVVQPLFGMFADRFGRKTAMLIFGASTTALTVPLLHAIGGTTDPFLAYALITAALLCVSFYTSISGLVKAEMFPAEVRALGVGLSYAIANALFGGSAEFVALSFKDWGVETWFFWYVTLMCAIAFLTSLQMPDSRRSGYLQGDGTA
>NC_010511.1|WP_012332761.1|3268778_3270095_+|ABC-transporter-substrate-binding-protein
MPLRPLRPLLAGLLVGLLAAAPLPAAAEGVAIALLTERTGPAAATGIPLANGFADYLTMLNQRDGGLGGQRVTVTECETGGNLERGLACYEEARRAGAVAINPGGVDLALALLGRSAADRIPLVSVPAGPALAAAGQRFPYAFAPPATAWDGLTVALAFLTNAPEGLEGRRVAYLHRDTPAGRDPVPVMEGLAGELGFSLRSYALPEPPEGAGIWRGVKAASPDILILDGSAGLAGDPVGDARAAGIPLNRVIALGSPSAEALRQAGPAARGFREITWHAATDSFPAFDQIDLLAIDAGLSRTEKDEATGLLYNRGVYAAVVTAEGIRNAQRRARGEPLDGDAVRRGLEAVQIDGARWKELGLTGFAATLRLSCGDHSGHLAGLVLEWNGAKWVQVSDKIAPLRQRLRPRLEAAARAFVEGAAAGGPWPERPEPCERS
>NC_010511.1|WP_012332760.1|3265679_3268682_+|PAS-domain-containing-sensor-histidine-kinase
MDEGALFEAKIAALTALPALARLTAGRPIACLFLDESAERVLHHSPAAKGLRDAIADPQGRIDRDLDVPRQLRGLRHLAPDGEKPRLSRLRIDPGGLAPPLVCACLVVSLPGDRRALALIPTDPLPALRPRRRHAVPAPAPPSPPVSGTGAAPMRFLWRSDAEGRIVEATEALTGLVGRTPLGRSWAELLADTVQGTSDDLAAALAARRTFRALPVLWRFDGTERGVAVDLSGAPRLGEGRAFAGFSGFGVIRPDRVAPMPPARAAAPAKPSLRERAAAVIAIGRASAPEEPGRAATWEPPPVPELPAFASLAGATLAGFAGMMAATPLNAFGLGWPFCLDEEGSAEPPTRKDAEPVAAAAAPRASAEPVAQAAPEPVVQAAPEPPLAPPEPDAAPSPGPETRPEPAAGDGEAGRRPEAAGHDETPAPAAEPAPEVPRPLAPGQLSLNEHAAFREIARILGARFAGDAPQDGPSPARDAEEAPRRAGAVTPFPALALARAPERGPSTAGEVARVLDRLPIGILVHQGEEVLLANRALLCLADYESAEALTAAGGAGSLFRGRDPASLAVGEGDPAGGADHPVVLATRTGEALPVAAVLTPVEWGGAPASLLALRRLPEEDPARHLRAAELERARQEARLRESEAVLDAVTDGVVTLDERGRVIALNKGAAALFGHEPREVSGEDLTVLFAQDGRPAIRAALERARAGEPASTEVAAEGGEPILALTLAPLAQEEPRRFSVLLRDVSAARRTEAELLRAKRAAEAASSQKSDFLATISHEIRTPLNAILGFTEVMMEEQFGPIGNERYRDYLRDIRSSGEHVVSLVTDLLDLAKIEAGHLDLHFTGVVLNDLVGASVSLMQPQAARQRVVVRTSFANGLRPVLGDQRSLRQAALNLIANAIKFTDAGGQVIVSTAMTDRGGVALRVRDTGIGMTPDEVETALQPFRQVATAQNRRGRGTGLGLPLTKALVEANRGTLRVSSRKHEGTLVEVLFPPARVLAI
>NC_010511.1|WP_012332759.1|3264997_3265441_-|phasin
MNTTPNYEIPAEMRDFAEKSVDQARKAFDSFISAARKTADTIQGSAEVARTNAQTMSTRSFAFAEQNVNAAFDLAQKLVRSRDVQEAMQHQAEFLRSQFAAIQSQAKEFGSMTQSAMQQSAENAKAAMQQGVDAAKSATNDVTHNAS
>NC_010511.1|WP_012332758.1|3264399_3264687_-|hypothetical-protein
MRRFVRALLASAALLAAGLAAPAAAQPAYGYDAPPPPSRRAVGYNCDAVQRGLSGPQPYSCPMPGPRPLGARCFCDVPIAPFSPPQPPAPGRVVP
>NC_010511.1|WP_012332757.1|3261720_3264051_+|RNA-binding-transcriptional-accessory-protein
MASITQRIAAELGAQEWQVKAAVDLLDGGATVPFVARYRKEATGTLDDAQLRTLEERLRYLRELEERRRAILDGIEAQGKLDEALRRQILAAETKARLEDLYLPYKPKRRTRAQIAREAGLGPLAEALLADPRRAPREAAAPFADAQKGVASPEAALEGARAILIERFAEDAELVGALRETFWKEGRLVSTLRAGKAEAGAKFADYFAFSEPLTRLPSHRVLALFRGEKEEVLDLRLDETPAGTEPGAPSRYEGRIALRHGIRDEGRPGDRWLAETVRAAWRTKLRLSIELDLRARLWEAAESEAVRVFAGNLRDLLLAAPAGARPTLGLDPGYRTGVKVAVVDGTSKVVATDTIYPHEPRRDWDRAVATLARLCRQHRVELVAIGNGTASRETDRLAGELIRLHPDLGLTKVMVSEAGASVYSASAYASQELPDLDVSLRGAVSIARRLQDPLAELVKIEPRSIGVGQYQHDLAEGKLSRSLDAVVEDCVNGVGVDVNTASAPLLARVSGLSERVAQAIVVHRDAHGPFRSRTALKKVAGLGPKAFELSAGFLRITGGDDPLDASGVHPEAYPVVRKILQATKSDIRAVIGNGSVLRSLDPRAFTDATFGLPTVTDILAELEKPGRDPRPSFRTASFQEGVETIGDLKPGMLLEGVVTNVAAFGAFVDVGVHQDGLVHISALSNSFVRDPRAVVKPGDVVRVKVLDVDVPRKRISLTMRLDDAPQARPGRDGARREPAPNPPRTETKPPRGETEPAGDGALAEALRRAGLDRPRR
>NC_010511.1|WP_012332756.1|3260719_3261655_+|DMT-family-transporter
MATLAPSLPAVLPSRPTLPRIGEQPLRGIGLVVLSTIFLSSSDAIAKYLSGSLPALEIAWLRYVGFVGVMLAAALLTRRRGRSPLRSARPGLQVLRGLALVGSALLFLSGLRYLPVAEATAISFVSPIFVTALSIPLLGETIGVRRWIAALVGLVGVLIILRPGTSAFQLAALLPVASSLFWALALVATRKINGYDAPQTTMTWSALVGFAVLTCLVPFAWVAPNLDEIAIGAAVGLISTTGHWIVTTAYRHAPASTLVPFSYTQIVWAALIGALAFGSRPDAFVGAGVLVIAASGLYTAHRERLRGARGA
>NC_010511.1|WP_012332755.1|3260146_3260371_+|YbdD/YjiX-family-protein
MALPSEPLRERWAALTRCVCDGARLMVGQGNYDAYLAHMRRTHPDQEPMNPTEFFRDRQNARFGVGGRGGFRCC
>NC_010511.1|WP_012332754.1|3258075_3260139_+|carbon-starvation-protein-A
MTAIQKHGPWALVGALGAAALALVATQRGETVNALWIVVAAVSVYLIAYRYYSLFIAERVMRLDPTRETPAVRHNDGLDYVPTDKYVLFGHHFAAIAGAGPLVGPVLAAQMGYLPGLLWILAGVVLAGAVQDFMVLFVSMRRDGRSLGELIRSELGTIPGVVALFGAFLIMVIILAVLALIVVKALAESPWGTFTVMATIPIALLMGVYSRWIRPGKIGEVSLIGFVLLMLAIVYGQTVAADPTLSRLFTFTGTQLCWMLIGYGFVASILPVWLLLAPRDYLSTFLKIGTIAALALGILVLAPHLQMPAVTKFVDGTGPVWSGSLFPFLFITIACGAVSGFHSLISSGTTPKLIDNEINARFIGYGGMLMESFVAVMALVSASVIDPGVYFTMNSPAAVVGTTPETAAAAVTKMGFAITPEAIQQTAADVGEHTVISRAGGAPTLAVGMAHIISNVVGGKAMMAFWYHFAILFEALFILTAVDAGTRAGRFMLQDLIGVAVPAFKDTASWGPSIVATALCVAFWGFFLYQGVTDPLGGVNTLWPLFGISNQMLAAIALTLCTVVIFKMKRERYAIVTILPTLWLVACTLTAGLQKVFSADPRVGFLAHADRYASAAAEGKVLAPAKSLDQMSQIVFNDRIDAVLAMLFVAVVVAIVAFGVKSCVAAYRASTWTALESDPRAVPAPAE
>NC_010511.1|WP_012332764.1|3272385_3274335_+|acetate--CoA-ligase
MTQRIVAVPAAVKERAYIDEAKYRAWYEASINDPEGFWREHGKRIDWFKPYTKVKETDFGPGNVSIRWFADGVTNVAHNCIDRHLATRGDQVAIIWEGDDPSESRSITYRELHAEVCRMANVLRNRGVGKGDRVTIYLPMIPEAAFAMLACARLGAIHSIVFGGFSPDSLAGRIEGCASKLVITADEGLRGGRKVPLKANVDAAIQRLPRDSVDHVIVVRRTGGSVAMEAGRDVYYDDAAREVTDECPVEHVEAEHPLFLLYTSGSTGQPKGVVHTTGGYLVYASMTHQYVFDYHEGEVYWCTADVGWVTGHSYIVYGPLANGATTLMFEGIPTYPSVSRFWDVVDKHKVNIFYTAPTAIRSLMGAGEEPVKKASRSTLRVLGSVGEPINPEAWEWYYRVVGDERCPIVDTWWQTETGGILISPLPGATALKPGSATQPFFGVKPVVVDGDNKVLEGACEGNLCLADSWPGQMRTVWGDHERFVQTYFSTFPGRYFSGDGCRRDEDGYYWITGRVDDVINVSGHRMGTAEVESSLVAHPKVSEAAVVGYPHSLKGQGIYAYVTLMNGEEPTEALRKELVAWVRKDIGPIASPDLIQFAPGLPKTRSGKIMRRILRKIAEDDFSSLGDTSTLADPGVVDDLIENRQNRAG
>NC_010511.1|WP_012332765.1|3274657_3274966_+|DUF485-domain-containing-protein
MSGPDTTRILNNPKFRELVAERTRFGWLLSAIMLGIYLGFVLLVAFAKGFLAMKIGAGVTSLGILLGVAVIVSAFVLTGIYVQRANGRFDDLTRDLNRELAR
>NC_010511.1|WP_012332766.1|3274962_3276654_+|cation-acetate-symporter
MIRLRLPALAALALLAAATAASAAGPDLGAVQKQNLNWSAIGMFLLFVLGTLGITYRAAAQTRSAADFYAAGGGISAGQNALAIAGDYMSAASFLGISGLVFSSGFDGLIYSIGFLVGWPIVLFLIAERLRNLGKFTFADVASFRLDQTQIRVLSATGTLVVVAFYLIAQMVGAGKLIQLLFGLDYLYAVVLVGILMIVYVAFGGMKATTWVQIIKACLLLAGATFMALAVLWRYGFNPEALFAAAVKEHPKHDAIMAPGGLVSDPISAISLGIGLMFGTAGLPHILMRFFTVSDAQAARKSVFYATGLIAYFYILTFIIGFGAITFLMNDPSYFKAGADGAYDRIAGLIGGTNMAAVHLANATGGALFLGFISAVAFATILAVVAGLTLAGASAVSHDLYAQVIARGRTSEQKEVRLSKLSAVVIGVVAIVLGYVFENQNVAFMVGLAFAVAASCNFPVLAMSILWKGTTTTGALVGGLVGLITAVAMVVLSKAVWVSTLGYSTALFPYDNPALFSMPIAFLVIWAVSKADASARARRERDSFEAQYVRSETGIGAATAHAH
>NC_010511.1|WP_012332767.1|3276793_3278314_-|undecaprenyl-phosphate-glucose-phosphotransferase
MTAFDVRDILKSAAAQPGEAGSRAAMPPAENLVPPRKGGPLSLVVLTGCVRAAEFGLVAATGIAAQLAVLHGLVPLHLGYLAAIFGLAALNLAVQQVAGSYGIRAFRAFFQFGLRVALGWSLVFLLAATVLFFAKLGDQYSRLWLGAYYLAGLVLLLGGRLALSIAVSDQMRQGRFDRRTAIVGGGEPAEALIKALEWQPDSGVKIVGVFDDRSDGRSSDVVAGYPKLGTVSDLVAYARNTRLDLIIFTLPISAEARILQMLSKLWVLPIDIRLSAHASKLRLRPRSYSYLGSVPVLDLFDKPIADWDVVVKAMFDRTVGGLMLVAFAPIMLAVALAVKLTSKGPVLFRQKRYGFNNELIEVYKFRSMYVDQSDAGAARLVTRGDPRVTPVGRFIRKTSLDELPQLFNVLKGDLSLVGPRPHALQAKAANTLYDQVVDGYFARHKVKPGLTGWAQINGWRGETDTSEKIQRRVEHDLYYIENWSVFFDLQILAMTPFALLKTENAY
>NC_010511.1|WP_012332768.1|3278415_3279822_-|glycosyltransferase-family-4-protein
MTGRAAVRERFVAVPQLRSADPAAAAAPLRGEPASPERILHVFRAPVGGLFRHVMDVARLQIAAGHAVGLFCDASTGGERAAAVLGEIAPALALGLTRVPMRRNPHPLDLAALARLHGVVGRLAPTVLHGHGSKGGLFARLVVTPRRVPDPVRAYTPHGGSFNYKPGTVLHRLYMAAEGGLTRRTDVFLFESAYIAGRYAAYVGETDRLVRVVQNGIDAAEFAPIAPAAEPCDFVYIGELRDAKGVPVLFDALARIRHALGRRLTLLVVGSGPDEAALRQRVRSLGLEDVVRFEPPQPIRSALSRGTIMVVPSFAESLPYVVLEAAAAAQPLVATNVGGIPEIFGPASGALVPPRDVEALAGALLRKLDQPAAERRDEAAGLSAFIRTRFSMQRMAEGILAGYRAARDARGPAAEAREAGESAPPDRAADAACAADAACAADAACAADAVRARDLPGTAEAPRRAGAR
>NC_010511.1|WP_012332769.1|3279964_3280537_-|polysaccharide-export-protein
MNRRVLLTGLAATLALGGCMHPEYRTEYLDATATGSIGTQYPLAAGDRLRVIVFGQDNLSNLYMVDGAGRIIMPLIGPVAVGGGTTLQAARAIEARLRDGYVREPHVTVEIDLYRPFFILGEVTTSGQYPYVNGMTVETAVAIAAGFGPRAARDYAVLTRQTRDGPVSGIVPLTYPVRPGDTILIKERWF
>NC_010511.1|WP_012332770.1|3280712_3282992_+|LPS-biosynthesis-protein
MLRASPAIPSPPPGAVTDPLPRHAERAAGEGVALGDIGRLLRRHWLAILLPTLAALAAAIAFVQLVPPRYTGEAKLLLESRDSALTRLQQERGDAAQPIDEQAVASQVQVVMSRDLAREAIRRLNLVGNREFDPTVEGIGSLQRLLIMLGLVPSPLDRDPEDRVLERYFDRLLVYSAGKSRILTIEFRSRDPDLAARGANTIADLYLASLAAAKVDTARFASTWLGSNVETLRSRVAEAEAKVEAFRARNGLIGGLAGSGGAQPIGAQQLTELSSQLTQARAAQADAAAKAKLIKDMIRDGRAFEIPDVANNELIRRLVEQRITLRAQLALEGRTLLPQHPRMKELTAQVTDLEGQIRAAADRTVRTLENDARIAGSRVESLQAAVDAQREVVAKGNSSEVQLRALEREAKVQREQLESYLARYREAAARDAESAAPADARVVSRAIVPDTPSFPKKLPIIGFTTAVAFLLAAGSVLARSLIADDPDDLRGRGRPRPRRAAVLTDVSARPDAPAPAPAAGGAAAALAEPEAGAAEEEDLGWGAPPASAQDPLPAPAMREEPYEFDALVARLASVESAGDGRRVLILGSGGAGEPEALALALGRSLARSARAVLLPLDAAAGGAPGLTDIVLGEAPFGEAIQRDPGSRLHRVGPGSHAPGVLLDEREGLGLTFDALGQAYDWILCVLRDDGRDPGTRALASATCLWMDAVVIASNAPADDADLVALYALAEGAGVPEVIVAQDRPPPPVAVPAYPLRRSA
>NC_010511.1|WP_012332771.1|3283208_3283715_+|L,D-transpeptidase
MIKQSGWAATIAVAATVACGPATAREIVAFEADVSPGSIVVRTSERRLYFVNGDGTAIRYPIAVGKSGKQWTGLAHVEGKYVQPAWSPPWEVKRDNPRLPNVIAGGSPRNPMGAAALTLDRGEYAIHGTNRPSSIGTFASYGCIRMYNQDVVDLFGRVAVGTPVIVTR
>NC_010511.1|WP_012332772.1|3284044_3284383_-|cupin-domain-containing-protein
MAGTTITKISGETAPRGPQGERVLAAGQRVAMRLWDKEPPTDKKPVVARDYETVGYVVAGRAELEISGRTIRLEPGDSWLVPAGAEHTYRVLETFTAVEATAPPARGAGPDA
>NC_010511.1|WP_012332773.1|3284435_3284810_-|PH-domain-containing-protein
MGLLDGLLGHGSDAAPADVARELDGMLVPGETVEVAFRVLRDLIVFTDRRLILVDRQGVTGRKISYLTVPYRAITSFSVENAGSFDLDSELKVWVSGRPDPISRTLRRGADIRGIQRAIAASLR

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Crispr_ID: NC_010511_19

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_010511_19

3439717-3439883

Orphan

Consensus_repeat	Method
TCGCTCAGGCGCCGCGCGGGCTTG	CRISPRCasFinder

2 spacers

The CRISPR arrays of NC_010511_19

>merge|NC_010511|19|3439717-3439883|CRISPRCasFinder
TCGCTCAGGCGCCGCGCGGGCTTGGCATACCCAATCCGCTCGATCCCTTCGGGATGGCGGATTGGGGCTTCGCTCAGGCGCCGCGCGGGCTTGTTACCCGCTCTCCGGACGTGATCGTCCGGACAGCGGATCAGTCCACCCACTCGCCCCGGCGCATCACCGGCTCG

>NC_010511|19|19|3439717-3439883|CRISPRCasFinder
TCGCTCAGGCGCCGCGCGGGCTTG	GCATACCCAATCCGCTCGATCCCTTCGGGATGGCGGATTGGGGCT
TCGCTCAGGCGCCGCGCGGGCTTG	TTACCCGCTCTCCGGACGTGATCGTCCGGACAGCGGATCAGTCCACCCAC
TCGCCCCGGCGCATCACCGGCTCG

Protein	Signature genes	Signature genes Name	Protein_function
NC_010511.1\|WP_012332913.1\|3433992_3434553_-\|transcriptional-repressor-NrdR	unknown	unknown	gnl\|CDD\|234774
NC_010511.1\|WP_012332915.1\|3436296_3436506_-\|SlyX-family-protein	unknown	unknown	gnl\|CDD\|377222
NC_010511.1\|WP_012332924.1\|3448465_3449095_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|370127
NC_010511.1\|WP_012332930.1\|3456309_3456939_+\|class-I-SAM-dependent-methyltransferase	unknown	unknown	gnl\|CDD\|379276
NC_010511.1\|WP_012332929.1\|3454669_3455773_+\|GSCFA-domain-containing-protein	unknown	unknown	gnl\|CDD\|378080
NC_010511.1\|WP_012332920.1\|3441147_3441444_-\|DUF2218-domain-containing-protein	unknown	unknown	gnl\|CDD\|378337
NC_010511.1\|WP_012332909.1\|3430027_3430459_+\|MerR-family-DNA-binding-transcriptional-regulator	unknown	unknown	gnl\|CDD\|133403
NC_010511.1\|WP_012332912.1\|3432799_3433996_-\|bifunctional-diaminohydroxyphosphoribosylaminopyrimidine-deaminase/5-amino-6-(5-phosphoribosylamino)uracil-reductase-RibD	unknown	unknown	gnl\|CDD\|273015
NC_010511.1\|WP_012332918.1\|3438649_3439621_+\|DUF1775-domain-containing-protein	unknown	unknown	gnl\|CDD\|377951
NC_010511.1\|WP_168169157.1\|3452229_3453099_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|376014
NC_010511.1\|WP_012332916.1\|3436602_3437883_-\|L,D-transpeptidase-family-protein	unknown	unknown	gnl\|CDD\|225536
NC_010511.1\|WP_012332926.1\|3450390_3451836_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|378931
NC_010511.1\|WP_150108667.1\|3449226_3450177_+\|hypothetical-protein	unknown	unknown	unknown
NC_010511.1\|WP_043701268.1\|3441455_3443810_-\|xanthine-dehydrogenase-family-protein-molybdopterin-binding-subunit	unknown	unknown	gnl\|CDD\|224446
NC_010511.1\|WP_012332923.1\|3446555_3448139_-\|hypothetical-protein	unknown	unknown	unknown
NC_010511.1\|WP_150108839.1\|3438147_3438576_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|237030
NC_010511.1\|WP_012332910.1\|3430814_3432104_+\|c-type-cytochrome	unknown	unknown	gnl\|CDD\|238121
NC_010511.1\|WP_012332914.1\|3434660_3435962_-\|serine-hydroxymethyltransferase	unknown	unknown	gnl\|CDD\|234571
NC_010511.1\|WP_012332928.1\|3453911_3454673_+\|hypothetical-protein	unknown	unknown	unknown
NC_010511.1\|WP_012332911.1\|3432200_3432836_-\|riboflavin-synthase	unknown	unknown	gnl\|CDD\|236455

Protein	Function_ID	Function_description	E-value
NC_010511.1\|WP_012332913.1\|3433992_3434553_-\|transcriptional-repressor-NrdR	gnl\|CDD\|234774	PRK00464, nrdR, transcriptional repressor NrdR.	1.96993e-86
NC_010511.1\|WP_012332915.1\|3436296_3436506_-\|SlyX-family-protein	gnl\|CDD\|377222	pfam04102, SlyX, SlyX. The SlyX protein has no known function. It is short less than 80 amino acids and is found close to the slyD gene. The SlyX protein has a conserved PPH(Y/W) motif at its C-terminus. The protein may be a coiled-coil structure.	1.44194e-18
NC_010511.1\|WP_012332924.1\|3448465_3449095_+\|hypothetical-protein	gnl\|CDD\|370127	pfam08795, DUF1796, Putative papain-like cysteine peptidase (DUF1796).	0.0043058
NC_010511.1\|WP_012332920.1\|3441147_3441444_-\|DUF2218-domain-containing-protein	gnl\|CDD\|378337	pfam09981, DUF2218, Uncharacterized protein conserved in bacteria (DUF2218). This domain, found in various hypothetical bacterial proteins, has no known function.	1.21504e-32
NC_010511.1\|WP_012332909.1\|3430027_3430459_+\|MerR-family-DNA-binding-transcriptional-regulator	gnl\|CDD\|133403	cd04776, HTH_GnyR, Helix-Turn-Helix DNA binding domain of the regulatory protein GnyR. Putative helix-turn-helix (HTH) regulatory protein, GnyR, and other related proteins. GnyR belongs to the gnyRDBHAL cluster, which is involved in acyclic isoprenoid degradation in Pseudomonas aeruginosa. These proteins share the N-terminal DNA binding domain with other transcription regulators of the MerR superfamily that promote transcription by reconfiguring the spacer between the -35 and -10 promoter elements. A typical MerR regulator is comprised of distinct domains that harbor the regulatory (effector-binding) site and the active (DNA-binding) site. Their conserved N-terminal domains contain predicted winged HTH motifs that mediate DNA binding, while the dissimilar C-terminal domains bind specific coactivator molecules.	1.62257e-36
NC_010511.1\|WP_012332912.1\|3432799_3433996_-\|bifunctional-diaminohydroxyphosphoribosylaminopyrimidine-deaminase/5-amino-6-(5-phosphoribosylamino)uracil-reductase-RibD	gnl\|CDD\|273015	TIGR00326, eubact_ribD, riboflavin biosynthesis protein RibD. This model describes the ribD protein as found in Escherichia coli. The N-terminal domain includes the conserved zinc-binding site region captured in the model dCMP_cyt_deam and shared by proteins such as cytosine deaminase, mammalian apolipoprotein B mRNA editing protein, blasticidin-S deaminase, and Bacillus subtilis competence protein comEB. The C-terminal domain is homologous to the full length of yeast HTP reductase, a protein required for riboflavin biosynthesis. A number of archaeal proteins believed related to riboflavin biosynthesis contain only this C-terminal domain and are not found as full-length matches to this model. [Biosynthesis of cofactors, prosthetic groups, and carriers, Riboflavin, FMN, and FAD].	7.54572e-81
NC_010511.1\|WP_012332918.1\|3438649_3439621_+\|DUF1775-domain-containing-protein	gnl\|CDD\|377951	pfam07987, DUF1775, Domain of unkown function (DUF1775). Domain found in bacteria with undetermined function. Its structure has been determined and is an immunoglobulin-like fold.	3.7907e-57
NC_010511.1\|WP_168169157.1\|3452229_3453099_-\|hypothetical-protein	gnl\|CDD\|376014	pfam18588, WcbI, Polysaccharide biosynthesis enzyme WcbI. Capsular polysaccharides (CPSs) are protective structures on the surfaces of many Gram-negative bacteria. wcbI is one of several genes in the CPS biosynthetic cluster whose deletion leads to significant attenuation of the pathogen. Structural analysis and biophysical assays suggest that WcbI functions as an acetyltransferase enzyme but it requires another functional module to carry out this function. WcbI adopts a predominantly helical fold where the N-terminal 100 amino acids form a ligand-binding domain and binds tightly to coenzyme A and its derivative acetyl-CoA.	4.11991e-44
NC_010511.1\|WP_012332916.1\|3436602_3437883_-\|L,D-transpeptidase-family-protein	gnl\|CDD\|225536	COG2989, COG2989, Uncharacterized protein conserved in bacteria [Function unknown].	4.46249e-128
NC_010511.1\|WP_012332926.1\|3450390_3451836_-\|hypothetical-protein	gnl\|CDD\|378931	pfam12708, Pectate_lyase_3, Pectate lyase superfamily protein. This family of proteins possesses a beta helical structure like Pectate lyase. This family is most closely related to glycosyl hydrolase family 28.	6.82774e-06
NC_010511.1\|WP_012332929.1\|3454669_3455773_+\|GSCFA-domain-containing-protein	gnl\|CDD\|378080	pfam08885, GSCFA, GSCFA family. This family of proteins are functionally uncharacterized. They have been named GSCFA after a highly conserved N-terminal motif in the alignment. Distant similarity to the pfam00657 lipases suggests these proteins are likely to be enzymes.	2.72219e-72
NC_010511.1\|WP_043701268.1\|3441455_3443810_-\|xanthine-dehydrogenase-family-protein-molybdopterin-binding-subunit	gnl\|CDD\|224446	COG1529, CoxL, Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL/CutL homologs [Energy production and conversion].	0
NC_010511.1\|WP_012332930.1\|3456309_3456939_+\|class-I-SAM-dependent-methyltransferase	gnl\|CDD\|379276	pfam13578, Methyltransf_24, Methyltransferase domain. This family appears to be a methyltransferase domain.	3.6641e-07
NC_010511.1\|WP_150108839.1\|3438147_3438576_+\|hypothetical-protein	gnl\|CDD\|237030	PRK12270, kgd, multifunctional oxoglutarate decarboxylase/oxoglutarate dehydrogenase thiamine pyrophosphate-binding subunit/dihydrolipoyllysine-residue succinyltransferase subunit.	0.000872572
NC_010511.1\|WP_012332910.1\|3430814_3432104_+\|c-type-cytochrome	gnl\|CDD\|238121	cd00200, WD40, WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from its N-terminus and the WD dipeptide at its C-terminus and is 40 residues long, hence the name WD40; between GH and WD lies a conserved core; serves as a stable propeller-like platform to which proteins can bind either stably or reversibly; forms a propeller-like structure with several blades where each blade is composed of a four-stranded anti-parallel b-sheet; instances with few detectable copies are hypothesized to form larger structures by dimerization; each WD40 sequence repeat forms the first three strands of one blade and the last strand in the next blade; the last C-terminal WD40 repeat completes the blade structure of the first WD40 repeat to create the closed ring propeller-structure; residues on the top and bottom surface of the propeller are proposed to coordinate interactions with other proteins and/or small ligands; 7 copies of the repeat are present in this alignment.	1.53818e-47
NC_010511.1\|WP_012332914.1\|3434660_3435962_-\|serine-hydroxymethyltransferase	gnl\|CDD\|234571	PRK00011, glyA, serine hydroxymethyltransferase; Reviewed.	0
NC_010511.1\|WP_012332911.1\|3432200_3432836_-\|riboflavin-synthase	gnl\|CDD\|236455	PRK09289, PRK09289, riboflavin synthase.	1.16216e-100

>NC_010511.1|WP_012332918.1|3438649_3439621_+|DUF1775-domain-containing-protein
MSCLLRGGLTALLIASSVPALAHAVLERRQAGPNQPYRAVVQIGHGCDGKATTRVTVTVPEGVVGAKPMPKPGWTLTTVTGPYSRAYPHYHGEIREGVKEITWSGGNLPDDQFDEFTFQARISDAFKPGETVYFPVRQECGEARIAWTEIPAAGQNAHDLKTPAPGVRIVAAAPVTAQQVAAQAAPAIQAGDLTIEGPWIRGTPGGAKVAGGYLRVTNRGSAPDRLVGASIPLAARGEIHEMSVANGVMRMAPVEGGLTIEPGKTVELKPGGYHLMFMDLTGAAKAGEAIEGTLTFARAGTVKVTFQVGAIGASGPAAQEHQH
>NC_010511.1|WP_150108839.1|3438147_3438576_+|hypothetical-protein
MPTERPAQHPSRRRGAAQDPSRRRAAARGAWPRRLRAPLAVLALYGLVLQAFLAGMAPGSAARAAGVVCAEHGPAAERPGPLAAHSCCAAACAAQATPLPPPAAARAAPGRAAIRLAWRPAAHALASRPPARPASARGPPLA
>NC_010511.1|WP_012332916.1|3436602_3437883_-|L,D-transpeptidase-family-protein
MLTRASLSGSLGLALLTAVALPALAEERGLAQAEWAQNYDSAATMRVQRSNTPILSPQTLAATEQMIERYRDIVARGGWQPVSGADRLRVGTKSPAVVALRQRLIVSGDLDPAAGSSPIYDSYVEAGVRRFQARHGLNETGAMNLTTVQAMNVPADVRLRQLELNAVRLRSYSGNLGARYVIVNIPAALVETVEGDHVATRHAAGVGKIDRQSPIMNAKIQEVNFNPYWTVPASIIKKDLIPKMQKEPNYLTDNKIRIFDGEREIAPSQVNWRSDEATRYRFRQDPGVDLNSMGFVRINIPNPHGVYMHDTPAKGIFGDDFRFVSSGCVRVQNVRDYVAWILQGTPQGNPETIEAIIQSGQRVDARPLAPIPVYWTYITAWSTPDGLVQFRDDIYKRDGVGAPTAAMTAAAQAPRNFADEDDGQTN
>NC_010511.1|WP_012332915.1|3436296_3436506_-|SlyX-family-protein
MAEPETRLDDLEIRVAHQERALEDLSRMVAAQWTQLDQLARQVAALQERLREMAERPTAPGEEPPPPHY
>NC_010511.1|WP_012332914.1|3434660_3435962_-|serine-hydroxymethyltransferase
MSAGTAKTPLSNSFFSASLADVDPELSRAVQQELGRQQHEIELIASENIVSRAVLEAQGSVLTNKYAEGYPGRRYYGGCEFVDIAENLAIERAKRLFGCDFANVQPNSGSQANQAVFMATMQPGDTFLGLDLAAGGHLTHGAPPNVSGKWFKPVSYTVRREDQRIDMEQVAKLAEEHKPKVIIAGGSGYPRHWDFAKFREIADSVGAVFFVDMAHFAGLVAGGVHPSPFPHAHVVTTTTHKTLRGPRGGMVLTNDEALAKKINSAVFPGLQGGPLMHVIAGKAVAFGEALSPDFKIYAKQVVENAKALADTIISGGFDITTGGTDNHLMLVDMRPKNLTGKAAEAALSRAGITCNKNGVPFDPQKPTVTSGIRLGTPAATSRGFGVAEFKKVGELIVTVLDGLARAGEAGDGAAEKKVLEEVHALTDRFPIYA
>NC_010511.1|WP_012332913.1|3433992_3434553_-|transcriptional-repressor-NrdR
MRCPYCGGLDTQVKDSRPSDDASAIRRRRICPDCGGRFTTFERVQLRDLTVVKRSGRRVPFDRDKLQRSIDVALRKRPVEADRVERLVSGIARQLESGGEAEVSSEAIGELVMEGLKALDDVAYVRFASVYKNFREARDFEELLGRLNGAGRPGGEPEPPDEAAPGPAAAPGEGGEAPARRARSRA
>NC_010511.1|WP_012332912.1|3432799_3433996_-|bifunctional-diaminohydroxyphosphoribosylaminopyrimidine-deaminase/5-amino-6-(5-phosphoribosylamino)uracil-reductase-RibD
MSASAEPGPDRAEPGPDRQASLDRRYMRLALALGRRHLGRTWPNPSVGAVLVAGPPGAERILAQGVTQPGGRPHAERVALAEAGEAARGATLYVTLEPCSHHGRTSPCADAVLAAGVARVVSAMNDPDPRVAGRGHGRLRAGGVAVTVGPCAEEAARDHAGHVMRVTTGRPALCLKLARTADGFAAGGAGRLLITGALANAEVHRLRAHSDAILVGIGTALADDPALTVRLPGLGDRSPLPVVLDPQLQLPPGARLLRPGGRAQTLILAGAAAPPAAERALREAGAEVLRLPAGPDGRPDLAASLRALGARGITRVFCEGGPTLADALAAADLVDSCLLLTGAAPLGQPGKPAIGPALAARLAGGLRRVAERPLGPDRLTTYARSSSCSPASSPTSDG
>NC_010511.1|WP_012332911.1|3432200_3432836_-|riboflavin-synthase
MFTGLVSDVGRVIAVEGGDRLRRITIACGYDPATIAVGASIACSGPCLTAVEIVPQEGGCRFTVDAAAETLARTTAGAWQPGTRLNLERSLRMGDELGGHLVTGHVDGLAEILAREAVTGGEGDASAASDRFVLRAPPDLARFIAEKGSVSLDGTSLTVNGVAGDTFTVLLIPHTLAATTWGERRAGDRVNLEVDLIARYAARLAEAQAAR
>NC_010511.1|WP_012332910.1|3430814_3432104_+|c-type-cytochrome
MTLRTLFVLLVLVALPARAEAPLRGHGGPVRALAVSPDGRVAISGSFDQSAILWAIDEGAALAVLRFHDGAVNAAAALPDGRMATGGEDGRVALWRLGSAEPVAVFADHAGPIAGLAVSPDGARLASASWDGTARIRPLPGADGPAPDRPGRVASEHRGNVNGVAFLPDGRLVTVGYDAALRVVPEDGPALTVTLPTPLNAVATAPDGEIAAAGADGTVRLLGPDGRERAAVAIPPRPVIALAVSPDGGRIAAATVGGAVAIIDRRAAKVLFTLVGPGLPVWSLAFRSDQELLTGGSDRLVRRWDLRTGEPIGPLAMAAPADGLAAFRGERGAEVFRACAACHTLGPDGGNRAGPTLHGIFGRRIATAPGYGYSEALRRLDLVWSPETVARLFEVGPSRYTPGTKMPEQTIGDPRDREALVRFLERATR
>NC_010511.1|WP_012332909.1|3430027_3430459_+|MerR-family-DNA-binding-transcriptional-regulator
MASGRTNTPASRSGRSASSRHTAPATLTIGDLAEEFGVTLRALRFYEAKGLLHPQRRGTTRLYTEEDRSRLATILRGKELGFTLREIAAMVDGEEIGEGGTTPTLALTPAQVEEQIAHLENQKAEIERALEALRSYGKAKASA
>NC_010511.1|WP_012332920.1|3441147_3441444_-|DUF2218-domain-containing-protein
MLTAQARVDTTQGSRYLTQLCKHWSHRFPETAFSPERGVVPFGEGREAVFEADSEGLTLRVRAPDAEALARLEAVVAEHLARFAFREDLGGIAWTRLA
>NC_010511.1|WP_043701268.1|3441455_3443810_-|xanthine-dehydrogenase-family-protein-molybdopterin-binding-subunit
MNARPDARDFAAPQQFGIGQPVPRAEDPVLVQGQGRYTDDLALEGQARAVFVRSPVAHGRLNGIDAEAARAMPGVLGVFTAADLDGYGRIGNSMAFTNQDGSPMRKPPQPSLATDRVRYAGEPVALVVAETLAEARDAAEAVILDIEDLPVVTTAEEAAAPDAPLIHDEAPGNLALDFALGDRAATDAAFAAAAHVTCLDLVNNRLVINPMEPRAAIGVYEPGDGRYTLHVGSQGVFGLRNSLADGVLKTGRDKVRVVTGHVGGSFGMKAPVYPEYLPLLHAAKVLGRPVKWTDLRSESFLSDHHGRDVAVTAELALDAEGRFLAFRVRGRGNMGAYLNPLSPLFQTVNIARNMVGVYRTPVFDVAVACLYTNTTPIGAYRGAGRPEGNYFIERLIENAAAETGRDRVALRRLNQIRPEDMPYAAPSGMTYDSGDFPAVLDRALAAADWDGFPARRAESEARGLLRGIGIGDYLEITAPPMNEMGGLRFEADGTVTIITGTLDYGQGHATPFAQVLHDRLGIPLDKVRLLQGDSDQLIAGGGTGGSKSLMASGAAIVEASALVIEKGRAAAAAVLEAGPADIVFEDGRFVVAGTDRGIGLLDLAAKLREGLPDPQAPRSLDVAHVHEASPSAFPNGCHVAEVEVDPETGVAAVVRYTTVNDFGTVVNPLLVEGQIHGGVIQGIGQALMERTAYDEQGQLVTGSFMDYCLPRAADAPPMSFESHPVPAKTNPLGVKGCGEAGCAGALPSVMNALVDALRARGVAHINMPATPRAIWAALREAEGA
>NC_010511.1|WP_012332923.1|3446555_3448139_-|hypothetical-protein
MPSDRQAGLVVPDPGDAAPAATWPPRHAFVVLDRLRQHLPAAAAAAHCVALSEKQIDALRGFEISDAAGRPDDALLARPILGAILDRDFVERFPKAVARLRQIAPQVPGADAVFDLSAAGPDGVAAWQLDRALGLSERFLADLGAGQLEIGRLQQIVTEHVEALHAAQRIVDQAVPPQPRLGLFLPPGDAVLCPAELPQVTGLSQNSKREFRAVHAFELHLAAADRQTRASVAIRLRAAHSRDLLGTWTVAAATLDPGWNRFDCPVTARPLDEPVEVELLWERGTAPRLALSLGEETADPRLRAVTSDGAVGQRPLALRIYAGVPGLRLPSRGWGRPADGEAAPEAPSHVRIDELLERAAFGGGLPEPRPELLRYMGVGSGLFLHPADEAPHVAVIRHVRIEGVRAVLADVALAHDEADPTEFGLFAAPSGLPVGPRPAPRGAAPRRWLRHGSPRPGDALAAREGFDGRAAWLRLRARETGQVLFEAPGPLGDCFDIYLGTRRAGAGTRHALAHFLHLAVVRGTRRA
>NC_010511.1|WP_012332924.1|3448465_3449095_+|hypothetical-protein
MYRRYVSLGQNCEVAFQFRRIFGTDSSSFFSWNVTSFEAAIRLIDDDFEGILEECNLERHADGRMVRDKGYDYLFHSPFATPEPRDDPDFAATLTRWRERTLHLVAKFREAYRAPWRTAYFYVTDQAACRSRAVRLRDALRARHEADNFVLVLLQDEGMREEPWGEPCLANHYLKRLAPWHDASDGHVSSYDRVFRAHPFDGAVAYAGY
>NC_010511.1|WP_150108667.1|3449226_3450177_+|hypothetical-protein
MRAFGASAIARNRPSVHRANGIVSAATDIPRTDLMRCDIVVVLYEAELALALLQAESIAKFIDPASVDRIIYCINDEDPRTTSDFIYSKIYPLLEKVGIRTCMLFREHFTLKTGNGYCLQQIQKLETAFRVQTDFYVAIDTKNFLVKNFSLSDLFVGSYPATFLESYEENDFRRYMKSMYLAYWSVPDPHTDIHLPAMATPFVFEADLVRGMIAEIERRERTSFGPFFERNFGASGGYSEFLLYSAYLYSQRQRAGRSRSFSLTSWGDTPVAPEEIHVLVDTARNNPDWKMCGIHKARLGPDPQRTLDEIRAAIGL
>NC_010511.1|WP_012332926.1|3450390_3451836_-|hypothetical-protein
MLRIATLASLLLSCSQVLAEQQGLPPLLSSGPDDVSEKSVQPAGALARRQLRDRFADEINAKDYGAKCDYDAGNRSGTDDTAALQAAIDAAQTSAAQGAGKRLLLPTGNCLTAPLTISGQIDVRGAGSHSTTLYLKAKSGKALLTFDAKGVDFSNKYGFPQGNVSLSHFRLTSQDGHSGPASAHGLELVRSQAGVFTPWLRLDDMVFYNLPGSGIASGPFQGFLEASRSTFSNNGGWGTDTNSTVDWRFLDCDWATNAAGNMRSSGDGQMFLLNPNIYASTGGYGIVAYSTDLKVVGGSIDYNAKGGMQFTADSTSLGRRVLLSGGTAFGGNSRSARGLHADIEVSGRGTALTLQNVRFASKPHKLDAQSQISYNLKFMDPGPLFVEIRDTLFAAGSVRGENVVSDLRRVSVVGQQDGSLLAVGGVISDGPVRQRPLVSDRSPTPSDIQDGYCAMVKRSDDGSLRMWCNDQGRLVSSAPLQ
>NC_010511.1|WP_168169157.1|3452229_3453099_-|hypothetical-protein
MAARIGFLGNCQAQTLDALSRHLGADFEFVEFSPVWLYTEQDEDRVLTQANRCDILFCQRIAEDYGVAFLRTSRLKAVMRERCFSWPNVYFEGYFPTIGYIYTSRGKITGPLSDYHLPIIREGWQNGRPVQAIVADITSPDGPLFAGDPAGASLAELESREEGLDIKMSDFIAERFREQKLFFTPNHPRDEVLFELLRRMMRAAGLNNPSSDRVGTFPYTLDSIQIPVMSGFFQRYGGSIQESDTIRGREISLEPETIGETATPRNYDWQGLIETYFRVYDAYARLGAL
>NC_010511.1|WP_012332928.1|3453911_3454673_+|hypothetical-protein
MSRYSILILGGSHMFPMKHAVDRAGPESTKNEYIFKPIADFRPDARIVDPIDGGWTDYTLNADLDAWMAQGIHADRLALTISGSDYLSLCISNRPVHFDVTLPEQPDLEEIEGALMIPHAEIMRKMRAEIRHIVLGVELIRARCSVPITYLESPPPIEDNDHIIAHAGWAAGGIQAWGVSRPILRYKLWRIHSRVVADACLANGIEFLPLPPEVLNERGYMSEKAIANDVMHANEWFGSRMAAQLDAVYGSAQ
>NC_010511.1|WP_012332929.1|3454669_3455773_+|GSCFA-domain-containing-protein
MTHPYRTAPDHSFWHRAVVEVDNVDPVVAPSFTIDRFSRVATAGSCFAQHIARYLQDVGIPRYTTEECHPEVGAYATDFHYHQYTARYGNVYTARQLYQLFLRAHGQFAPLESAWPTERGFADPFRPGIPEGFASRRELERDVAKHLAAVRRMFEELDVLIFTLGLTESWVSLLDGSVFPSCPGTIAGTFEPAKYRFHNFTMREVVDDLTSFIAALRSVNKRAKVLLTVSPVPLVATANGGHVLTATTYSKSVLRVAAEEVAAAHAEVDYFPSYEIIMGPQARGRFFAQDLRTVTEEGVATVMNLFRRHYLGSMHSFRSPVPAAALSRPLPSPSAASPAGAPGDTEAARRQLELICEEMANDDRARA
>NC_010511.1|WP_012332930.1|3456309_3456939_+|class-I-SAM-dependent-methyltransferase
MLSLNEIGLKHGTDKASNVHDYLNFYEKRLAHLREESFTLFEIGVYQGASVRMWEEFFPNATIVGLDINPATQAAEAGRIKMRIGDQSSVKFLFSVINEFGPPRIVIDDGSHRWDHQIQTLNILLPFVPAGGRYIVEDIHTSSDHMKKDYQGFSQVSGFEYLSRLSHLICTHDVAGPSEIFDNFLYSHYQEIESVEFARRTAIINKKSF

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Crispr_ID: NC_010511_20

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_010511_20

3661571-3661665

Orphan

Consensus_repeat	Method
GGGCTTCGCTCAGGCGCCGCGCGGGCTGGTGAT	CRISPRCasFinder

1 spacers

The CRISPR arrays of NC_010511_20

>merge|NC_010511|20|3661571-3661665|CRISPRCasFinder
GGGCTTCGCTCAGGCGCCGCGCGGGCTGGTGATCCGCTTGATCCCTTCGGGATGGCGGATTCGGGCTTCGCTCAGGCGCCGCGCGGGCTCGTGAT

>NC_010511|20|20|3661571-3661665|CRISPRCasFinder
GGGCTTCGCTCAGGCGCCGCGCGGGCTGGTGAT	CCGCTTGATCCCTTCGGGATGGCGGATTC
GGGCTTCGCTCAGGCGCCGCGCGGGCTCGTGAT

Protein	Signature genes	Signature genes Name	Protein_function
NC_010511.1\|WP_012333114.1\|3669722_3670811_-\|HlyD-family-efflux-transporter-periplasmic-adaptor-subunit	unknown	unknown	gnl\|CDD\|273776
NC_010511.1\|WP_150108670.1\|3655179_3655926_+\|FCD-domain-containing-protein	unknown	unknown	gnl\|CDD\|224715
NC_010511.1\|WP_168169196.1\|3661697_3662675_-\|glycosyltransferase-family-2-protein	unknown	unknown	gnl\|CDD\|366154
NC_010511.1\|WP_150108671.1\|3668852_3669233_+\|hypothetical-protein	unknown	unknown	unknown
NC_010511.1\|WP_012333101.1\|3652921_3653920_-\|glucokinase	unknown	unknown	gnl\|CDD\|234716
NC_010511.1\|WP_012333116.1\|3671973_3673302_-\|glycosyl-transferase-family-protein	unknown	unknown	gnl\|CDD\|237800
NC_010511.1\|WP_012333112.1\|3663974_3665609_-\|glycosyltransferase	unknown	unknown	gnl\|CDD\|133055
NC_010511.1\|WP_012333109.1\|3659706_3661350_-\|choline-dehydrogenase	unknown	unknown	gnl\|CDD\|235000
NC_010511.1\|WP_012333113.1\|3665931_3667695_+\|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|224055
NC_010511.1\|WP_012333099.1\|3651952_3652444_+\|ferritin-like-domain-containing-protein	unknown	unknown	gnl\|CDD\|153118
NC_010511.1\|WP_012333105.1\|3657056_3657995_+\|dihydrodipicolinate-synthase-family-protein	unknown	unknown	gnl\|CDD\|188630
NC_010511.1\|WP_012333104.1\|3656085_3656961_-\|LysR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|176118
NC_010511.1\|WP_012333100.1\|3652514_3652928_+\|glyoxalase	unknown	unknown	gnl\|CDD\|319942
NC_010511.1\|WP_012333108.1\|3659220_3659700_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|153092
NC_010511.1\|WP_012333111.1\|3662962_3663964_-\|polysaccharide-deacetylase-family-protein	unknown	unknown	gnl\|CDD\|213023
NC_010511.1\|WP_012333115.1\|3670826_3671951_-\|UDP-N-acetylglucosamine-2-epimerase-(non-hydrolyzing)	unknown	unknown	gnl\|CDD\|376768
NC_010511.1\|WP_012333098.1\|3651378_3651813_-\|hypothetical-protein	unknown	unknown	unknown
NC_010511.1\|WP_012333117.1\|3674177_3675263_+\|chemotaxis-sensory-transducer	unknown	unknown	gnl\|CDD\|333767
NC_010511.1\|WP_012333119.1\|3675687_3675918_+\|hypothetical-protein	unknown	unknown	unknown
NC_010511.1\|WP_012333102.1\|3653994_3654945_-\|3-hydroxyacyl-CoA-dehydrogenase-family-protein	unknown	unknown	gnl\|CDD\|224170

Protein	Function_ID	Function_description	E-value
NC_010511.1\|WP_012333114.1\|3669722_3670811_-\|HlyD-family-efflux-transporter-periplasmic-adaptor-subunit	gnl\|CDD\|273776	TIGR01730, COG0845:_Membrane-fusion_protein, RND family efflux transporter, MFP subunit. This model represents the MFP (membrane fusion protein) component of the RND family of transporters. RND refers to Resistance, Nodulation, and cell Division. It is, in part, a subfamily of pfam00529 (Pfam release 7.5) but hits substantial numbers of proteins missed by that model. The related HlyD secretion protein, for which pfam00529 is named, is outside the scope of this model. Attributed functions imply outward transport. These functions include nodulation, acriflavin resistance, heavy metal efflux, and multidrug resistance proteins. Most members of this family are found in Gram-negative bacteria. The proposed function of MFP proteins is to bring the inner and outer membranes together and enable transport to the outside of the outer membrane. Note, however, that a few members of this family are found in Gram-positive bacteria, where there is no outer membrane. [Transport and binding proteins, Unknown substrate].	3.74243e-09
NC_010511.1\|WP_150108670.1\|3655179_3655926_+\|FCD-domain-containing-protein	gnl\|CDD\|224715	COG1802, GntR, Transcriptional regulators [Transcription].	7.26312e-39
NC_010511.1\|WP_168169196.1\|3661697_3662675_-\|glycosyltransferase-family-2-protein	gnl\|CDD\|366154	pfam00535, Glycos_transf_2, Glycosyl transferase family 2. Diverse family, transferring sugar from UDP-glucose, UDP-N-acetyl- galactosamine, GDP-mannose or CDP-abequose, to a range of substrates including cellulose, dolichol phosphate and teichoic acids.	5.32362e-33
NC_010511.1\|WP_012333101.1\|3652921_3653920_-\|glucokinase	gnl\|CDD\|234716	PRK00292, glk, glucokinase; Provisional.	2.49144e-95
NC_010511.1\|WP_012333116.1\|3671973_3673302_-\|glycosyl-transferase-family-protein	gnl\|CDD\|237800	PRK14716, PRK14716, glycosyl transferase family protein.	0
NC_010511.1\|WP_012333112.1\|3663974_3665609_-\|glycosyltransferase	gnl\|CDD\|133055	cd06433, GT_2_WfgS_like, WfgS and WfeV are involved in O-antigen biosynthesis. Escherichia coli WfgS and Shigella dysenteriae WfeV are glycosyltransferase 2 family enzymes involved in O-antigen biosynthesis. GT-2 enzymes have GT-A type structural fold, which has two tightly associated beta/alpha/beta domains that tend to form a continuous central sheet of at least eight beta-strands. These are enzymes that catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. Glycosyltransferases have been classified into more than 90 distinct sequence based families.	1.793e-40
NC_010511.1\|WP_012333109.1\|3659706_3661350_-\|choline-dehydrogenase	gnl\|CDD\|235000	PRK02106, PRK02106, choline dehydrogenase; Validated.	0
NC_010511.1\|WP_012333113.1\|3665931_3667695_+\|ABC-transporter-ATP-binding-protein	gnl\|CDD\|224055	COG1132, MdlB, ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms].	2.02242e-101
NC_010511.1\|WP_012333099.1\|3651952_3652444_+\|ferritin-like-domain-containing-protein	gnl\|CDD\|153118	cd07909, YciF, YciF bacterial stress response protein, ferritin-like iron-binding domain. YciF is a bacterial protein of unknown function that is up-regulated when bacteria experience stress conditions, and is highly conserved in a broad range of bacterial species. YciF has a ferritin-like domain. Ferritin-like, diiron-carboxylate proteins participate in a range of functions including iron regulation, mono-oxygenation, and reactive radical production. These proteins are characterized by the fact that they catalyze dioxygen-dependent oxidation-hydroxylation reactions within diiron centers; one exception is manganese catalase, which catalyzes peroxide-dependent oxidation-reduction within a dimanganese center. Diiron-carboxylate proteins are further characterized by the presence of duplicate metal ligands, glutamates and histidines (ExxH) and two additional glutamates within a four-helix bundle. Outside of these conserved residues there is little obvious homology. Members include bacterioferritin, ferritin, rubrerythrin, aromatic and alkene monooxygenase hydroxylases (AAMH), ribonucleotide reductase R2 (RNRR2), acyl-ACP-desaturases (Acyl_ACP_Desat), manganese (Mn) catalases, demethoxyubiquinone hydroxylases (DMQH), DNA protecting proteins (DPS), and ubiquinol oxidases (AOX), and the aerobic cyclase system, Fe-containing subunit (ACSF).	9.7911e-65
NC_010511.1\|WP_012333105.1\|3657056_3657995_+\|dihydrodipicolinate-synthase-family-protein	gnl\|CDD\|188630	cd00408, DHDPS-like, Dihydrodipicolinate synthase family. Dihydrodipicolinate synthase family. A member of the class I aldolases, which use an active-site lysine which stabilizes a reaction intermediate via Schiff base formation, and have TIM beta/alpha barrel fold. The dihydrodipicolinate synthase family comprises several pyruvate-dependent class I aldolases that use the same catalytic step to catalyze different reactions in different pathways and includes such proteins as N-acetylneuraminate lyase, MosA protein, 5-keto-4-deoxy-glucarate dehydratase, trans-o-hydroxybenzylidenepyruvate hydratase-aldolase, trans-2'-carboxybenzalpyruvate hydratase-aldolase, and 2-keto-3-deoxy- gluconate aldolase. The family is also referred to as the N-acetylneuraminate lyase (NAL) family.	1.24955e-55
NC_010511.1\|WP_012333104.1\|3656085_3656961_-\|LysR-family-transcriptional-regulator	gnl\|CDD\|176118	cd08427, PBP2_LTTR_like_2, The C-terminal substrate binding domain of an uncharacterized LysR-type transcriptional regulator, contains the type 2 periplasmic binding fold. LysR-transcriptional regulators comprise the largest family of prokaryotic transcription factor. Homologs of some of LTTRs with similar domain organizations are also found in the archaea and eukaryotic organisms. The LTTRs are composed of two functional domains joined by a linker helix involved in oligomerization: an N-terminal HTH (helix-turn-helix) domain, which is responsible for the DNA-binding specificity, and a C-terminal substrate-binding domain, which is structurally homologous to the type 2 periplasmic binding proteins. As also observed in the periplasmic binding proteins, the C-terminal domain of the bacterial transcriptional repressor undergoes a conformational change upon substrate binding which in turn changes the DNA binding affinity of the repressor. The genes controlled by the LTTRs have diverse functional roles including amino acid biosynthesis, CO2 fixation, antibiotic resistance, degradation of aromatic compounds, nodule formation of nitrogen-fixing bacteria, and synthesis of virulence factors, to a name a few. This substrate-binding domain shows significant homology to the type 2 periplasmic binding proteins (PBP2), which are responsible for the uptake of a variety of substrates such as phosphate, sulfate, polysaccharides, lysine/arginine/ornithine, and histidine. The PBP2 bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap. After binding their specific ligand with high affinity, they can interact with a cognate membrane transport complex comprised of two integral membrane domains and two cytoplasmically located ATPase domains. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis.	2.12956e-51
NC_010511.1\|WP_012333100.1\|3652514_3652928_+\|glyoxalase	gnl\|CDD\|319942	cd08354, VOC_like, uncharacterized subfamily of vicinal oxygen chelate (VOC) family. The vicinal oxygen chelate (VOC) superfamily is composed of structurally related proteins with paired beta.alpha.beta.beta.beta motifs that provide a metal coordination environment with two or three open or readily accessible coordination sites to promote direct electrophilic participation of the metal ion in catalysis. VOC domain is found in a variety of structurally related metalloproteins, including the bleomycin resistance protein, glyoxalase I, and type I ring-cleaving dioxygenases. A bound metal ion is required for protein activities for the members of this superfamily. A variety of metal ions have been found in the catalytic centers of these proteins including Fe(II), Mn(II), Zn(II), Ni(II) and Mg(II). The protein superfamily contains members with or without domain swapping. The proteins of this family share three conserved metal binding amino acids with the type I extradiol dioxygenases, which shows no domain swapping.	8.78021e-45
NC_010511.1\|WP_012333108.1\|3659220_3659700_+\|hypothetical-protein	gnl\|CDD\|153092	cd00618, PLA2_like, PLA2_like: Phospholipase A2, a super-family of secretory and cytosolic enzymes; the latter are either Ca dependent or Ca independent. PLA2 cleaves the sn-2 position of the glycerol backbone of phospholipids (PC or phosphatidylethanolamine), usually in a metal-dependent reaction, to generate lysophospholipid (LysoPL) and a free fatty acid (FA). The resulting products are either dietary or used in synthetic pathways for leukotrienes and prostaglandins. Often, arachidonic acid is released as a free fatty acid and acts as second messenger in signaling networks. Secreted PLA2s have also been found to specifically bind to a variety of soluble and membrane proteins in mammals, including receptors. As a toxin, PLA2 is a potent presynaptic neurotoxin which blocks nerve terminals by binding to the nerve membrane and hydrolyzing stable membrane lipids. The products of the hydrolysis (LysoPL and FA) cannot form bilayers leading to a change in membrane conformation and ultimately to a block in the release of neurotransmitters. PLA2 may form dimers or oligomers.	1.71923e-05
NC_010511.1\|WP_012333111.1\|3662962_3663964_-\|polysaccharide-deacetylase-family-protein	gnl\|CDD\|213023	cd10918, CE4_NodB_like_5s_6s, Putative catalytic NodB homology domain of PgaB, IcaB, and similar proteins which consist of a deformed (beta/alpha)8 barrel fold with 5- or 6-strands. This family belongs to the large and functionally diverse carbohydrate esterase 4 (CE4) superfamily, whose members show strong sequence similarity with some variability due to their distinct carbohydrate substrates. It includes bacterial poly-beta-1,6-N-acetyl-D-glucosamine N-deacetylase PgaB, hemin storage system HmsF protein in gram-negative species, intercellular adhesion proteins IcaB, and many uncharacterized prokaryotic polysaccharide deacetylases. It also includes a putative polysaccharide deacetylase YxkH encoded by the Bacillus subtilis yxkH gene, which is one of six polysaccharide deacetylase gene homologs present in the Bacillus subtilis genome. Sequence comparison shows all family members contain a conserved domain similar to the catalytic NodB homology domain of rhizobial NodB-like proteins, which consists of a deformed (beta/alpha)8 barrel fold with 6 or 7 strands. However, in this family, most proteins have 5 strands and some have 6 strands. Moreover, long insertions are found in many family members, whose function remains unknown.	2.92765e-31
NC_010511.1\|WP_012333115.1\|3670826_3671951_-\|UDP-N-acetylglucosamine-2-epimerase-(non-hydrolyzing)	gnl\|CDD\|376768	pfam02350, Epimerase_2, UDP-N-acetylglucosamine 2-epimerase. This family consists of UDP-N-acetylglucosamine 2-epimerases EC:5.1.3.14 this enzyme catalyzes the production of UDP-ManNAc from UDP-GlcNAc. Note that some of the enzymes is this family are bifunctional, in these instances Pfam matches only the N-terminal half of the protein suggesting that the additional C-terminal part (when compared to mono-functional members of this family) is responsible for the UPD-N-acetylmannosamine kinase activity of these enzymes. This hypothesis is further supported by the assumption that the C-terminal part of rat Gne is the kinase domain.	1.37155e-129
NC_010511.1\|WP_012333117.1\|3674177_3675263_+\|chemotaxis-sensory-transducer	gnl\|CDD\|333767	pfam00015, MCPsignal, Methyl-accepting chemotaxis protein (MCP) signalling domain. This domain is thought to transduce the signal to CheA since it is highly conserved in very diverse MCPs.	8.26485e-13
NC_010511.1\|WP_012333102.1\|3653994_3654945_-\|3-hydroxyacyl-CoA-dehydrogenase-family-protein	gnl\|CDD\|224170	COG1250, FadB, 3-hydroxyacyl-CoA dehydrogenase [Lipid metabolism].	5.95622e-73

>NC_010511.1|WP_012333109.1|3659706_3661350_-|choline-dehydrogenase
MTASEGEAPVDFGTYDHIVVGAGSAGCVLANRLSADPRRSVLVLEAGGRDNWIWFHIPAGYLFAIGNKRADWLFTTEAEAGLNGRQLAYPRGKVIGGSSAINAMIYMRGQAADYDGWRQLGLSGWGWDDVLPFFLKHEDHIAPPNAFHRSGGEWRVEPPRIRWAVLDAIRDAAEAAGIRKIPDFNTGDNEGSSYFQVNQRRGRRWSAARGFLKPALGRPNLRLETGIHVERVLIEEGRAAGVVFARPDGRRALARARGEVVLSAGAVASPKLLELSGIGDGARLRDLGIGLVHHAPGVGENLQDHLQIRPVYKVTGVPTLNLTYANLFKRAWMGIEYALFRTGPLTMAPSQVGVFAKSSPDYATANLEFHFQPLSLDKWGEGLHPFGAFTASVCNLRPSSRGSVHAASPDPAAPPAIRPNYLSTDEDRRVAVDALKLTRRIVAQPPLARYRPEEYRPGPEVTSDEGLLRAAGDLGTTIFHPVGTARMGPDHEPGAVLDARMRVRGVRGLRVVDASAMPRITSGNTNSPTIMMAEKGAAMILEDARGA
>NC_010511.1|WP_012333108.1|3659220_3659700_+|hypothetical-protein
MRRLALPLLLAIGVATSAAAQPPLSGREPALLFHGNYCGPGNNAPLLPVDALDLACARHDACTPDGGLPSRACNARLAREAEAVARDASQPQDLRALAGMVATGAALLPTAPGAAPRPALSMRAAPLAGPVTLIAPRPAADPDALEPDSPDLEPADEAE
>NC_010511.1|WP_012333105.1|3657056_3657995_+|dihydrodipicolinate-synthase-family-protein
MSLTPSAQGVYPIAPTPFHPDGSIDVASIDGLTDFYVGCGATGLTVLGVMGEAPKLDHAEGLAVATRFIRRARGLPVIVGVSAPGFAAMASLARGAMEAGAAGVMIAPPSTLRTDDQIAAYYRQAVEAIGPDVPFVIQDYPLTFSVVMTPGIIRRIVTENPSCVMLKHEDWPGLEKISALRAFEAEGAMRPISILCGNGGLFLDFECERGADGAMTGYAFPDMLVDVVRLSKAGERDRAHDLFDAHLPLLRYEQQPGIGLAVRKYVMARRGLIASDAQRKPAGGLGPAARAEVEYLLGRLARHDPRARVRPL
>NC_010511.1|WP_012333104.1|3656085_3656961_-|LysR-family-transcriptional-regulator
MNTRFLATLCAIAEAGSLAGAARALGLASATVAEQVQALERELGVRLVGRQGRAVTLTDEGRAVVAAGRDILARVADLAQVAQLGRLRGGLRVGAVSTALISILPPALKLMAERSPEIALHIAPGTSSQLARMLEAGEIDCALTVQPRFALAKGWGWLPVRREPLTLVSPVGLRRDTTDAYLSAAPLIRMDRRSPTGAIVTDYLNSRRIVPNELFELDAPDTITILVSLGLGIALLPDYGFRSSDDRPIRKIPIADRAFVRSIGILHRRGARIALIDALHAALCDSCARPG
>NC_010511.1|WP_150108670.1|3655179_3655926_+|FCD-domain-containing-protein
MRARAHPCVRVDRSGDRCDGLAMSRTADPERSLGPTRAEEIRRRLADEIVRGLRAPGTPLDEAELAALFGVSRTPVREALRQLEVEGFATSRPRRGALVSTIAPAALAEMFFVMAELEALCCRLAAQAMTAEEGAELERARRLCEAAVAADAIEEYREANDRFHDLIYRASHNGFLMEQTRAVRRRVAPFRRAQFQSSGRLAKSLAEHERIAASLRARDGETAAREVRAHIFTVEYAYYHQKAQGPAS
>NC_010511.1|WP_012333102.1|3653994_3654945_-|3-hydroxyacyl-CoA-dehydrogenase-family-protein
MSEIAVIGAGLMGHGIALVLALGGHGVRLTDSRAEALERVPGLMGSALATLREAQAVAAEWTPERLEAAVRLSPDLAGTVAGADLVIEAITENPEAKRALFAELDRLCAPGTILASNTSYLDVFPLIPEARQARALVAHWYTPPYIVDLVDVVPGPRTDPAVVETMRELVLGLGQVPIVLKRFVPGYVANRIQSAISAEVYHLLDEGLASPRDIDDAIIHGLALRIPVLGHLAKADFTGIELLRHALANASYSPPPARTASPALDALAAEGRTGVMAGHGFFDWGGRDPAELFRDRDRRLLALKRAMREIGRMEGR
>NC_010511.1|WP_012333101.1|3652921_3653920_-|glucokinase
MFDFPVLIGDIGGTNARFALVPRPGAAPLPLDHVQTGAFPDPSAAIRHALAKGGAAPRSAILAIAGRVDGPAVPLTNAAWVIEGERIGRDFGLGACVLVNDYVPVAAGAAALDPLDGDGAALSAVGPALAPGRGSRLVLGPGTGFGAAALVPFGEQLAIVSTEAGHTDFGPSDAAEAALWPALERIEGRITVEALLSGPGLCRLYAAVSGGRALAPEAVTARGLSGEDPAAAETLALFAKLLGRLCGDLALTFLATGGVYIGGGIAPRLLPVLRRGAFRQAFVHKPPFVAMMERIPTCVITIADPAFTGLAALASRPERFAYDGQVWRAPAQ
>NC_010511.1|WP_012333100.1|3652514_3652928_+|glyoxalase
MPEVAGVLETVLYVDDLERAAAFWGGPMGLPCIHSDHRMRAFDVAGRGVLLLFPRGGSLHPIETPGGTIPPHDGQGPLHLALAIPAEALGAWEAHLAEAGIAVEGRTHWPRGGTSLYFRDPDGHLVELATPGLWKGY
>NC_010511.1|WP_012333099.1|3651952_3652444_+|ferritin-like-domain-containing-protein
MMAGKDLRTLFLHQLKDTYFAENAILKALPKMAEAAQTDALRGAFGVHLQETREQVKRLDQVFRSLGEKPEGVTCKAIQGIIAEGEEVMQEFGGSGALDAGLIAAAQAVEHYEITRYGTLIAWARQLGLAEAESLLKETLVEEENTDEVLSELAEEAVNPAAA
>NC_010511.1|WP_012333098.1|3651378_3651813_-|hypothetical-protein
MPSLPDPETILTLLRRATETVRHATARAEAAEARARRIAGQVRPLVERVERVLREAADREAAARREAAEARARCGAAEALLAAERERVRRLEARLAESQARIARARRILAEASSGQEGPGVSAPGEADVRGVPNGFAGDPASLH
>NC_010511.1|WP_168169196.1|3661697_3662675_-|glycosyltransferase-family-2-protein
MPAYNAEKTIDATLVSVRSQSHRDLEILVVDDGSTDRTTAIVARHAALDARIRLIRQANGGVARARNEGIAQARGAFVAPVDADDLCSPDRIAKQLVAIEAAGADAALAYTWSAQIDERGIIIVADWKPAHEGRVYEALCTMNFIGNGSATLMRTAAVREVGGYDASLRDRGAQGCEDWALYLAISRKYNFALVPEFLTGYRQASDNMSSNHRRMYKSFLLVARDHLRRDAGSAALLREANVNVLSWLLSLALRDRKFLTAAEFAFSLLMRSPIAVVRSFRHYRVVYGGFKGHGRNKDRKLPTSPLIGQFFKVGAADTCSIEPGS
>NC_010511.1|WP_012333111.1|3662962_3663964_-|polysaccharide-deacetylase-family-protein
MGFLKRQLRRAWPFGSGPRPVILMYHRVAELDSDPWQLAVSPRHFEAHLEHLRRSRTPMDLAAFVAALTAGTLPRDAVALTFDDGYVDNLRQAEPRLAAAGIPATLFLTTAAIGRPEPFWWDELAHLILDRSAPADLSVGIADGRYRLQFGEPDRLDRDRRRWRAWESPRTAREAAYQALWRVIRDASRPEREGAMATLRRALGGAGAACEEERAMTPDEVRGMARRGVLTIGGHTLSHPALPTLTPAEQRWEIAEGKRAAEEMSGQRVDGFAYPYGAMDASAQAAVAACGFAWACSTVATAVEPADFQRYALPRIAAPNAGKAVLARALGDG
>NC_010511.1|WP_012333112.1|3663974_3665609_-|glycosyltransferase
MEAPITTPSNEKSIQLIAGSDVTVVITTYNHAHFLGEALASVAAQTRVPEEVIVVDDGSSDDPAAIVARWPGVRLIRQPNQGLSSARNTGLAQARTTYILFLDADDMLRPAAIAQGLAAFARSPGVAFVYGAHERVDRDGNPLGGAVYHAMAGDPVAALLHHNIVGMHATVLYRRDILSAAGGFDTRLRRCEDYDVYLRLAQAHAIASHPTVVARYRWHDSNMSYDFRAMRDAALAVHARYRPAAEADSLRRETWSEGRRFWRRYYAGEALRAGGRISPRGVAAAARLDPLWTAGELARRAAIRLGGAVSRRAGYRLRRRLVGRASPPVGRVDWGDFGTPWPVSEDFGWDRGLPVDRFYIERFLEGAAADIRGRVLEIGDDAYSRRFGGARVERQDILHVEAGNPRATLIGDISRAGTLPQAAFDCIVLTQTLHLIFDMASALRQLHGALRPGGVLLLTVPGISPIDRGEWSGTWFWSLTPAALTRLLDEVFGAGAATVRSHGNVYAATAFLQGLALSEVDPTKLDVADASYPVIVAARAARRP
>NC_010511.1|WP_012333113.1|3665931_3667695_+|ABC-transporter-ATP-binding-protein
MFLFDKHRPLVNIARRYLWSVPAVTVLGLISTGLEGIGVGLIAPLVVSLTSSESVASSGPFRVLMQFGADLPANTRLVYICAGIAGLVILKNAVAFLNTLLISFVDGRASHDVRVALAHQLLTVEYGFFLVEPPGRIINILANESWRASEAIRAFFQALSSAASLILFGIFLLWSEWRLGLAVGLGVLAIRHAIARITRRVNDLSSQMSAENESLASAMMISVLAMRPIRIFGQEAREEARFRDASEKVRALIFAMERKSALIQPLSESLRTCVLVLLLAGTVRVAADVPLPVLATFLVLLQRTQPHLATFEAARAKISQTSGAVQEVEWLLAVTRKAAPRSLGQVKPSFDRDIRFADVSFRYHSSSEIRTIDSASFVIRAGSSTALIGPSGSGKSTIINLLCGLLEPTSGEILVDGTSLDRLDRSEWLNLIGIAGQDTEIIEGTIAENIAYGAPHVGQAEIEEAARVADADAFVRSLPLGYATNVGSRGLNLSGGQRQRIGLARAIVRKPRLLILDEATSAVDGLSERTIMDLLASSRRSCTMLVVSHRMSTLSRCDSAIVLEGGRVVRASPMTDVMRDREAIPIP
>NC_010511.1|WP_150108671.1|3668852_3669233_+|hypothetical-protein
MPVEALPYPNNQPRLSHKDKSSTVATCDPFRIKAQLRRRDLTYYLTSVQIANIQNQNKEAPRRRAEVVFTVENDEGHPTVATTMLVDISYEDGITFGELKEEAIAQATKIIEVIHGNLSAKSASPA
>NC_010511.1|WP_012333114.1|3669722_3670811_-|HlyD-family-efflux-transporter-periplasmic-adaptor-subunit
MSELKVSQMSWGKLFRVLVTGTAVIGSGAIGFYYYSSGVLVLNADGLVTRDRVYVATPYDARVREVFVRPGDTVVAGQKIAVVDSPSISKTLAEFSIERAKISSRVAQLEARTTIVAAMVPVARAGAKQANEFMADLNKAKSSGLALNRSLHEVTAASFTATERLLTMISEKISLDTELASNRAALAEITSASDNLRRVYADGVLTAPVSGVVGSAIASPGEVLTPGSNRLASIYTGTSFVLAYMPESYLFEAAEGQSVQVSAHRQSVSGQIARILPVTDALPPEFQPPNRARDRGQVVKISLNDADRFAVDQKIRVSSCIVTGCKESYVEQAKARVILTFGNLLSSPAHAERIKREASVKP
>NC_010511.1|WP_012333115.1|3670826_3671951_-|UDP-N-acetylglucosamine-2-epimerase-(non-hydrolyzing)
MRILIAFGTRPEIIKLGPVYRALVAQPGIQVDAYWTGQHIELAAGLLQLFNITVRYHGEAVMSEPGLAEKFGLMTNQIAAALRATHYDWIVVQGDTATASAAASAGFLSRVPVAHVEAGLRTGDLSSPWPEEYNRRVISVSSSLHFSPTAESAANLLREGVDPKSVITVGNTVVDALLYARENTAPNYAPVDSGIAGIPLNKKLILATMHRRENIGSPMREVLRALRSLAEDGDKVVALPVHLNPEVRREVLAILGGIENVCLLAPLQYLDFVHLLSRAWLVISDSGGVQEEAPTFGLPILITRTTTERPEVVAAGFGSLVGSDHDVITAMARERTRGRTPHRLGGPNPFGDGHASVRIADALIARTLRRSAAA
>NC_010511.1|WP_012333116.1|3671973_3673302_-|glycosyl-transferase-family-protein
MSEVIPIAMFAVSSLINISSLDDAFIDLMAFGISRRGLPSLSGKSAIPRIAVFVANWHEEDVLGRMVEGNLARITCPDVSLYLGVYPNDTGTLRVARELECKYPSRVTVIVNTLSGPTSKGQMLNEMFRQVFEREDCPDIAVLHDSEDVIDPRTFSIYAEYSKDHDFIQVPVFSLDRGEGLPVASTYMDEFAERHTREMIVRNAVGAAIPSAGVGTAMTRKLLQHFLATRGQVLMSGTVTEDYILGVEAKRAGFRSAFAAVSADDERGLNYVATREFFPKSLSASIKQKTRWVYGINFEATHKLGWKGDAWDKYFFVRDRKGVVTNLLPPVSLMILLLIAGGIIDLSGVPESLEPFLSASVTVNLVALFTRYVVRVAACREVYGTYDLLGIAYRWPVGLYINAAAVFRAWKTYIGESEFATKPIGWSKTAHDLPEDFGKATR
>NC_010511.1|WP_012333117.1|3674177_3675263_+|chemotaxis-sensory-transducer
MKARTTEIRPGESARVSLTQVAGETESVRQIVTDKTRAIQAVTAQVKILALNALIEAARAGEQGRGFSVVAQEVRAIGAQIEAIAGALDAELAGRITGLQGMMKDLADAAQGERLVDLALNAIELIDRNLYERTCDVRWWATDPAIVACAEEPTPERVAYATERLGVILSAYTVYLDLWVCDAAGRVVANGRPDRFPAIRGASVAHEEWFRRAAALPNGDTYVAAEVATRPLLQGAQAATYCASIRTDGRSDGRPRGVLAIHFDWEPQARAIVAGVRVAPEDRERTRVLLVDAGGRVLAASDGRGLLTETLRLDARERTGGFDQDAGGAVTAFHRTPGYETYAGLGWYGVITQHPARRAAR
>NC_010511.1|WP_012333119.1|3675687_3675918_+|hypothetical-protein
MSVPIEVARPQGHEEARLIMVRDVLAAIVVRVHADPDLGIDEGWFLKVGFGPCDHEGVIFSCVEESQSWAEKLLGG

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Crispr_ID: NC_010511_21

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_010511_21

3891727-3891791

Orphan

Consensus_repeat	Method
GCCGCGGCCTCGGCTTGGGCCTC	CRISPRCasFinder

1 spacers

The CRISPR arrays of NC_010511_21

>merge|NC_010511|21|3891727-3891791|CRISPRCasFinder
GCCGCGGCCTCGGCTTGGGCCTCGACTTGGGCCCCGACTTGGGCCTCGGCTTGGGCTGCGGCCTC

>NC_010511|21|21|3891727-3891791|CRISPRCasFinder
GCCGCGGCCTCGGCTTGGGCCTC	GACTTGGGCCCCGACTTGG
GCCTCGGCTTGGGCTGCGGCCTC

Protein	Signature genes	Signature genes Name	Protein_function
NC_010511.1\|WP_012333277.1\|3897378_3898593_+\|sulfotransferase-family-protein	unknown	unknown	unknown
NC_010511.1\|WP_012333275.1\|3896303_3896798_+\|GNAT-family-N-acetyltransferase	unknown	unknown	gnl\|CDD\|366181
NC_010511.1\|WP_012333282.1\|3904040_3904847_-\|carbon-nitrogen-hydrolase-family-protein	unknown	unknown	gnl\|CDD\|143587
NC_010511.1\|WP_012333272.1\|3894692_3895241_+\|phage-tail-protein	unknown	unknown	gnl\|CDD\|227020
NC_010511.1\|WP_012333265.1\|3876980_3878144_+\|mandelate-racemase/muconate-lactonizing-enzyme-family-protein	unknown	unknown	gnl\|CDD\|239442
NC_010511.1\|WP_012333267.1\|3879304_3880933_+\|DUF3459-domain-containing-protein	unknown	unknown	gnl\|CDD\|200470
NC_010511.1\|WP_012333281.1\|3902486_3904028_-\|amidohydrolase-family-protein	unknown	unknown	gnl\|CDD\|238623
NC_010511.1\|WP_012333279.1\|3899373_3901359_+\|glycosyltransferase	unknown	unknown	gnl\|CDD\|133005
NC_010511.1\|WP_012333278.1\|3898756_3899377_+\|class-I-SAM-dependent-methyltransferase	unknown	unknown	gnl\|CDD\|369778
NC_010511.1\|WP_012333280.1\|3901395_3902265_-\|alpha/beta-fold-hydrolase	unknown	unknown	gnl\|CDD\|235628
NC_010511.1\|WP_012333263.1\|3873879_3875325_-\|aldehyde-dehydrogenase	unknown	unknown	gnl\|CDD\|143423
NC_010511.1\|WP_012333268.1\|3886692_3887367_-\|GntR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|224715
NC_010511.1\|WP_012333274.1\|3895762_3896299_+\|phage-tail-protein	unknown	unknown	gnl\|CDD\|227020
NC_010511.1\|WP_012333276.1\|3896794_3897382_+\|aspartyl-beta-hydroxylase	unknown	unknown	gnl\|CDD\|377460
NC_010511.1\|WP_012333262.1\|3873001_3873853_-\|p-hydroxycinnamoyl-CoA-hydratase/lyase	unknown	unknown	gnl\|CDD\|236383
NC_010511.1\|WP_012333270.1\|3890458_3891652_+\|aminotransferase-class-V-fold-PLP-dependent-enzyme	unknown	unknown	gnl\|CDD\|178031
NC_010511.1\|WP_012333266.1\|3878173_3879142_-\|hypothetical-protein	unknown	unknown	unknown
NC_010511.1\|WP_012333261.1\|3870530_3872654_-\|acetate--CoA-ligase-family-protein	unknown	unknown	gnl\|CDD\|223972
NC_010511.1\|WP_012333264.1\|3875408_3875852_+\|winged-helix-turn-helix-transcriptional-regulator	unknown	unknown	gnl\|CDD\|224759
NC_010511.1\|WP_012333269.1\|3887395_3890347_-\|FAD-binding-oxidoreductase	unknown	unknown	gnl\|CDD\|223354

Protein	Function_ID	Function_description	E-value
NC_010511.1\|WP_012333275.1\|3896303_3896798_+\|GNAT-family-N-acetyltransferase	gnl\|CDD\|366181	pfam00583, Acetyltransf_1, Acetyltransferase (GNAT) family. This family contains proteins with N-acetyltransferase functions such as Elp3-related proteins.	3.33395e-11
NC_010511.1\|WP_012333282.1\|3904040_3904847_-\|carbon-nitrogen-hydrolase-family-protein	gnl\|CDD\|143587	cd07197, nitrilase, Nitrilase superfamily, including nitrile- or amide-hydrolyzing enzymes and amide-condensing enzymes. This superfamily (also known as the C-N hydrolase superfamily) contains hydrolases that break carbon-nitrogen bonds; it includes nitrilases, cyanide dihydratases, aliphatic amidases, N-terminal amidases, beta-ureidopropionases, biotinidases, pantotheinase, N-carbamyl-D-amino acid amidohydrolases, the glutaminase domain of glutamine-dependent NAD+ synthetase, apolipoprotein N-acyltransferases, and N-carbamoylputrescine amidohydrolases, among others. These enzymes depend on a Glu-Lys-Cys catalytic triad, and work through a thiol acylenzyme intermediate. Members of this superfamily generally form homomeric complexes, the basic building block of which is a homodimer. These oligomers include dimers, tetramers, hexamers, octamers, tetradecamers, octadecamers, as well as variable length helical arrangements and homo-oligomeric spirals. These proteins have roles in vitamin and co-enzyme metabolism, in detoxifying small molecules, in the synthesis of signaling molecules, and in the post-translational modification of proteins. They are used industrially, as biocatalysts in the fine chemical and pharmaceutical industry, in cyanide remediation, and in the treatment of toxic effluent. This superfamily has been classified previously in the literature, based on global and structure-based sequence analysis, into thirteen different enzyme classes (referred to as 1-13). This hierarchy includes those thirteen classes and a few additional subfamilies. A putative distant relative, the plasmid-borne TraB family, has not been included in the hierarchy.	1.10925e-31
NC_010511.1\|WP_012333272.1\|3894692_3895241_+\|phage-tail-protein	gnl\|CDD\|227020	COG4675, MdpB, Microcystin-dependent protein [Function unknown].	1.51745e-56
NC_010511.1\|WP_012333265.1\|3876980_3878144_+\|mandelate-racemase/muconate-lactonizing-enzyme-family-protein	gnl\|CDD\|239442	cd03326, MR_like_1, Mandelate racemase (MR)-like subfamily of the enolase superfamily, subgroup 1. Enzymes of this subgroup share three conserved carboxylate ligands for the essential divalent metal ion (usually Mg2+), two aspartates and a glutamate, and conserved catalytic residues, a Lys-X-Lys motif and a conserved histidine-aspartate dyad. This subgroup's function is unknown.	0
NC_010511.1\|WP_012333267.1\|3879304_3880933_+\|DUF3459-domain-containing-protein	gnl\|CDD\|200470	cd11331, AmyAc_OligoGlu_like, Alpha amylase catalytic domain found in oligo-1,6-glucosidase (also called isomaltase; sucrase-isomaltase; alpha-limit dextrinase) and related proteins. Oligo-1,6-glucosidase (EC 3.2.1.10) hydrolyzes the alpha-1,6-glucosidic linkage of isomalto-oligosaccharides, pannose, and dextran. Unlike alpha-1,4-glucosidases (EC 3.2.1.20), it fails to hydrolyze the alpha-1,4-glucosidic bonds of maltosaccharides. The Alpha-amylase family comprises the largest family of glycoside hydrolases (GH), with the majority of enzymes acting on starch, glycogen, and related oligo- and polysaccharides. These proteins catalyze the transformation of alpha-1,4 and alpha-1,6 glucosidic linkages with retention of the anomeric center. The protein is described as having 3 domains: A, B, C. A is a (beta/alpha) 8-barrel; B is a loop between the beta 3 strand and alpha 3 helix of A; C is the C-terminal extension characterized by a Greek key. The majority of the enzymes have an active site cleft found between domains A and B where a triad of catalytic residues (Asp, Glu and Asp) performs catalysis. Other members of this family have lost the catalytic activity as in the case of the human 4F2hc, or only have 2 residues that serve as the catalytic nucleophile and the acid/base, such as Thermus A4 beta-galactosidase with 2 Glu residues (GH42) and human alpha-galactosidase with 2 Asp residues (GH31). The family members are quite extensive and include: alpha amylase, maltosyltransferase, cyclodextrin glycotransferase, maltogenic amylase, neopullulanase, isoamylase, 1,4-alpha-D-glucan maltotetrahydrolase, 4-alpha-glucotransferase, oligo-1,6-glucosidase, amylosucrase, sucrose phosphorylase, and amylomaltase.	0
NC_010511.1\|WP_012333281.1\|3902486_3904028_-\|amidohydrolase-family-protein	gnl\|CDD\|238623	cd01298, ATZ_TRZ_like, TRZ/ATZ family contains enzymes from the atrazine degradation pathway and related hydrolases. Atrazine, a chlorinated herbizide, can be catabolized by a variety of different bacteria. The first three steps of the atrazine dehalogenation pathway are catalyzed by atrazine chlorohydrolase (AtzA), hydroxyatrazine ethylaminohydrolase (AtzB), and N-isopropylammelide N-isopropylaminohydrolase (AtzC). All three enzymes belong to the superfamily of metal dependent hydrolases. AtzA and AtzB, beside other related enzymes are represented in this CD.	1.57047e-73
NC_010511.1\|WP_012333279.1\|3899373_3901359_+\|glycosyltransferase	gnl\|CDD\|133005	cd02511, Beta4Glucosyltransferase, UDP-glucose LOS-beta-1,4 glucosyltransferase is required for biosynthesis of lipooligosaccharide. UDP-glucose: lipooligosaccharide (LOS) beta-1-4-glucosyltransferase catalyzes the addition of the first residue, glucose, of the lacto-N-neotetrase structure to HepI of the LOS inner core. LOS is the major constituent of the outer leaflet of the outer membrane of gram-positive bacteria. It consists of a short oligosaccharide chain of variable composition (alpha chain) attached to a branched inner core which is lined in turn to lipid A. Beta 1,4 glucosyltransferase is required to attach the alpha chain to the inner core.	7.23086e-27
NC_010511.1\|WP_012333278.1\|3898756_3899377_+\|class-I-SAM-dependent-methyltransferase	gnl\|CDD\|369778	pfam08242, Methyltransf_12, Methyltransferase domain. Members of this family are SAM dependent methyltransferases.	0.00623762
NC_010511.1\|WP_012333280.1\|3901395_3902265_-\|alpha/beta-fold-hydrolase	gnl\|CDD\|235628	PRK05855, PRK05855, SDR family oxidoreductase.	2.2679e-36
NC_010511.1\|WP_012333263.1\|3873879_3875325_-\|aldehyde-dehydrogenase	gnl\|CDD\|143423	cd07105, ALDH_SaliADH, Salicylaldehyde dehydrogenase, DoxF-like. Salicylaldehyde dehydrogenase (DoxF, SaliADH, EC=1.2.1.65) involved in the upper naphthalene catabolic pathway of Pseudomonas strain C18 and other similar sequences are present in this CD.	0
NC_010511.1\|WP_012333268.1\|3886692_3887367_-\|GntR-family-transcriptional-regulator	gnl\|CDD\|224715	COG1802, GntR, Transcriptional regulators [Transcription].	4.02727e-42
NC_010511.1\|WP_012333274.1\|3895762_3896299_+\|phage-tail-protein	gnl\|CDD\|227020	COG4675, MdpB, Microcystin-dependent protein [Function unknown].	6.36596e-63
NC_010511.1\|WP_012333276.1\|3896794_3897382_+\|aspartyl-beta-hydroxylase	gnl\|CDD\|377460	pfam05118, Asp_Arg_Hydrox, Aspartyl/Asparaginyl beta-hydroxylase. Iron (II)/2-oxoglutarate (2-OG)-dependent oxygenases catalyze oxidative reactions in a range of metabolic processes. Proline 3-hydroxylase hydroxylates proline at position 3, the first of a 2-OG oxygenase catalyzing oxidation of a free alpha-amino acid. The structure of proline 3-hydroxylase contains the conserved motifs present in other 2-OG oxygenases including a jelly roll strand core and residues binding iron and 2-oxoglutarate, consistent with divergent evolution within the extended family. This family represent the arginine, asparagine and proline hydroxylases. The aspartyl/asparaginyl beta-hydroxylase (EC:1.14.11.16) specifically hydroxylates one aspartic or asparagine residue in certain epidermal growth factor-like domains of a number of proteins.	1.89153e-14
NC_010511.1\|WP_012333262.1\|3873001_3873853_-\|p-hydroxycinnamoyl-CoA-hydratase/lyase	gnl\|CDD\|236383	PRK09120, PRK09120, p-hydroxycinnamoyl CoA hydratase/lyase; Validated.	0
NC_010511.1\|WP_012333270.1\|3890458_3891652_+\|aminotransferase-class-V-fold-PLP-dependent-enzyme	gnl\|CDD\|178031	PLN02409, PLN02409, serine--glyoxylate aminotransaminase.	3.48303e-140
NC_010511.1\|WP_012333261.1\|3870530_3872654_-\|acetate--CoA-ligase-family-protein	gnl\|CDD\|223972	COG1042, COG1042, Acyl-CoA synthetase (NDP forming) [Energy production and conversion].	4.34308e-105
NC_010511.1\|WP_012333264.1\|3875408_3875852_+\|winged-helix-turn-helix-transcriptional-regulator	gnl\|CDD\|224759	COG1846, MarR, Transcriptional regulators [Transcription].	1.21859e-12
NC_010511.1\|WP_012333269.1\|3887395_3890347_-\|FAD-binding-oxidoreductase	gnl\|CDD\|223354	COG0277, GlcD, FAD/FMN-containing dehydrogenases [Energy production and conversion].	1.64667e-77

>NC_010511.1|WP_012333270.1|3890458_3891652_+|aminotransferase-class-V-fold-PLP-dependent-enzyme
MTHAPGRHFLQIPGPTNTPLPVLAAIARPTIDHRGPDFARLGRTVLAEIRPVFGTTNPVVIYPASGTGAWEAALANTLSPGDRVLMFETGWFATLWSRLAKRLGIEAEFLKGDWRSGVDAAAIEARLAEDAGHAIKAVCIVHNETSTGVTSNVAAVRRALDQARHPALLLVDAISSLGSIDYRHDAWGVDVTIAGSQKGLMLPPGLSFNAVSDKALAASRSARLPNSYWNWEEMLAANATGTFPYTPSTNLLQGLAVALEMLRAEGLPAVFARHDRAAAATRACVAHWGFEIQCRNPEDYSSALTAVRLPEGHSADALRAEILERCNMSLGNGLGPLADRVFRIGHLGDFHDLMVTGTLAGVELGLRIRGIPHRPGGVEAALQVLAGNAGPAALAAE
>NC_010511.1|WP_012333269.1|3887395_3890347_-|FAD-binding-oxidoreductase
MHGSLGNPGAAGREAGSSAPLERRLREAVSGEVLFGAFDRGRYATDASIYQIMPRGVVLPRTRADIAAVLAVAAEHEVPVVMRGGGTSQNGQPIGAGLVVDCSRHLDGVLAYDPAAGTVTVEPGTVLERLNARLKADGWFFPVEPSTASRCTIGGMVGNNSCGARSLRYGKMVDNVLGLDGLRADGTAFSLSAEGAPGAEDLAARMRRLAEAERDEIEARFPKVQRRVGGYNLDALLAERPNLAHLLVGSEGTLAATTAVTLRLARLPAHRVMGVCHFPSFRAAMETVPALVALDPVAVELVDNNVLVLGADIPLFRATLADIARGRPDCLLLVEFAGESEAALARDLARLDACMADHGFAGAVVPVVEPARQRTVWGMREACLNIMMSMRGDAKPVSFIEDCAVPLEHLADYTDAVTALFARHGTRGTWYAHASVGCLHVRPILNLKQEAGIAAMRAIAEETADLVRRFKGSYSGEHGDGISRSEFIAPLFGPRLTRAFEAVKDAFDPENRLNPGKIVRPLRMDDRGLMRFPAGYRVAAPAPALDWSAWGGLGGAVEMCNNNGTCRSLAGGVMCPSYRATRSEEHLTRGRANTLRLALSGQLGPDALTAPETKRALDLCVSCKGCRRECPTGVDMARMKIEVLHHYHARHGLPLRERLVAHLPRYAGLAARLAPLLNLRNRVPALARLGERHLGLSARRALPRWRRPFAEAGEVAHPADVAGDFRDVVLFADTFNRAFERENLEAAETVLRRAGYRLHRVAAPGGARPLCCGRTYLSVGDVPRARAEARRTLDALLPFVRAGARVVGLEPSCLLTLRDEFAALLPPAEAAELAAASLLFEELLAADLAAGRIALPLADQGGRVAHLHGHCHQKAFGAMGAVETVLRQVPGLDLRLIESSCCGMAGAFGYGAATYDASVAMAELSLFPALRRADPDDLVVADGTSCRHQIRDGLDREALHVARVLCAALRPEPRQKAARPIPL
>NC_010511.1|WP_012333268.1|3886692_3887367_-|GntR-family-transcriptional-regulator
MTRVETGISRRYLHDEVAERLRALILSGELEPRARLNEILLTERFGISRTPLREAIKILATEGLLELLPNRGARVASISTQEIEEILEVVAALEALAGELACRHITEAELEAIAAHHAAMVEAWRREDDPAYFTLNRRIHEAIMAASRNATLASLYAGLSGRIQRARYSAHKTPEQWRRAVEEHDAMLAHLRARDGEALARVMRAHIRGKKPVIAAAYGSEAGN
>NC_010511.1|WP_012333267.1|3879304_3880933_+|DUF3459-domain-containing-protein
MDRPTPDPDALAPTAPRSPASLAWWQERVLYQIFVPSFQDADGDGFGDLAGLISRLDHLSDLGIGAVWLTPIYATPFEDAGYDVTDFTQVGARFGDLPTFDRLLAGLHARDIRLILDFVPNHTSDRHPWFRESRASRASPRRDWYVWRDPGPEGSAPNNWLSRFGGSAWTHDARTDQSYYHAFLPSQPDLNWRNPEVRRAMHEVMRFWLRRGVDGFRIDAAAVLAEDAALRDDPPNPDFDGDTPPPERFRRLRTDSQVVTLDYLAELRRVVEEFPDRVLLGEVDTAPDKLPGFYGEGTRRLHLPLNYRLLSVPWKAAALAGAVDAYLDALPPGAWPNWVLGSHDKARIASRVGPAQARVAALMLLTLPGTPMLFAGDEIGMPNVPVPVDRMRDPFERLVPGYGLSRDPSRVPLPWTAGPGGGFSAVEPWLPAPCPPPVAPVAAQARDPASLLSLYRAVIALRRRRPEFRAGGYARLRAEGGVFAYARNLDGVRGIVALNLTPSRLEAEVGTGRILLSTRPGRGGACEGRLCLEPHEGVVIAA
>NC_010511.1|WP_012333266.1|3878173_3879142_-|hypothetical-protein
MSLSKKVKVGLDETRILILGSQILLGFQLQGAFRPALDRLPPHDRLVWAAALALITLTVALLITPSVQHRMVEGGRDTRRILRVIGRCAGLSLAPFSLALGADVFLAVERVLGPWAALPAGLLIFGLAVTFWFGLGAARARRAGARERERARRAPEPGPTPLEVKLEQMLTEARVMLPGAQALLGFQLVITFTDSFEALPFAARAVHMAALGLIALTVIWLVAPAAFHRIVYAGEDAPEVHRLGTRFLLAASVTLALGIAADLGVVLAKVLESGRAGLAGGILCLCGLLGLWHAAPLVLRRRAAGAGRGDAPRAAGEPGGPA
>NC_010511.1|WP_012333265.1|3876980_3878144_+|mandelate-racemase/muconate-lactonizing-enzyme-family-protein
MRIVDVREITKPIASPIRNAYIDFTKMTTSLVAVVTDVVRDGRRVVGYGFNSNGRYGQGGLIRERFRDRLLEAPPESLLSEAGDTLDPHRIWAALMRNEKPGGHGERSVAVGTLDMAVWDAAAKIAGKPLFRMLAEREGREADPRVFVYAAGGYYYPGKDDAALRAEMRSYLDRGYTVVKMKIGGASLAEDRRRIEAVLAEIGGRARLAVDANGRFDLETAIAYAKMLRDYPLFWYEEAGDPLDYALQAALGGFYPGPMATGENLFSHQDARNLLRYGGMRPDRDWLQFDCALAYGLVEYLRILDVLAEFGWSPARCIPHGGHQMSLNIAAGLGLGGNESYPDLFQPYGGFPDGVRVEDGHIVMPDLPGIGFEGKAELIRVMRDLAE
>NC_010511.1|WP_012333264.1|3875408_3875852_+|winged-helix-turn-helix-transcriptional-regulator
MTSKPPRLHSPLNDLLGYQLRRASNALMAELGQDLGRLGLTPTEASVLVLVAANPGVTQTEIGSELSIKRANMAPITARLDALGLVLRQPVDGRAQGLFVTQAGAARADEVRNAMTAHDRKIMALLPKDLRDGLRASLPVFWRQAGR
>NC_010511.1|WP_012333263.1|3873879_3875325_-|aldehyde-dehydrogenase
MMPMAGVSGGVAAAAERLLVRHDPITGEVASRVPACGPDEAVAVADAAAAAFPAWADLGPNARRAALMRAAAQIEARAEAFVAAMMGEVGATAGWARFNVTLAASMLREAAALTTQVGGEVIPSDKPGCLAMAMREPAGIVLGIAPWNAPVILGVRAVAVPLACGNAVILKGSELCPRTHALIAEALRAAGLPEGVVGYVANRPEEAGEVVGALIDHPAVRRVNFTGSTAVGRVVAKRAAETLTPCLLELGGKAPLLVLEDADLDEAVRAAAFGAFMNQGQICMSTERIIVVDAVAEAFVARFRAKVETLAVGDPRDGRAPLGAVVDRRTVAHVGALVEAALAEGAVLVAGGPAAGVLMPAHAVDRVTPDMRLFREESFGPVVAIVRARDEAHAVALANDTDYGLSAAVFTRDTARGLRVARRIRSGICHVNGPTVHDEAQMPFGGVKASGYGRFGGRAGIDAFTELRWITIETQPGHYPI
>NC_010511.1|WP_012333262.1|3873001_3873853_-|p-hydroxycinnamoyl-CoA-hydratase/lyase
MSQERSERDTVAFEVIDRVAWVRFNRPEKRNCMSPKLNRRMMEVIDELEFRQDVGVLVLTGEGSAWSAGMDLKEYFRETEAQGLAGTRKAQRESYGWWRRLRWYQKPTIAMVNGWCFGGGYGPLFACDLAFAAEEAQFGLSEINWGILPGGGASKVAVELTSFRNAMYHALTGEAIDGREAAAWGFVNEAVPAGQLRARVSEVAALLLAKNPTALKATKDAIRRVREMTYDNAEDYLVRAQEAANSYDGEGRKEGIRQFIDEKSYKPGLGAYDLRRTASANPA
>NC_010511.1|WP_012333261.1|3870530_3872654_-|acetate--CoA-ligase-family-protein
MTDLARLLRPASVAIVGASDKPGALGASVLANLERAGYCGAIHLVNPNRAEIGGRPCLPCVEALPDGVDAAVLAIPRAAVLPAIRALAARRAGAAVVFSAGFAEGGEAGRAEQDEIARIAGEAGMVVEGPNCLGLVNFVDGVPLTFVELPGTRLAGRPGIGIVSQSGAMAAVLAVTLQARGLGLSYSVSTGNEAASGVEDYVEFLVEDPDTRVIVLIVEQFRKPARFLAAARRAHAAGKPVVLLHPGRGEAARRSAATHTGALAGDYDLMRLKVEDAGVSLVPTLEELADVAEILLRCPPPGSGGSAVLVESGAYKALTLDLAEEVGLDLPAIADADSPGLRAALPDFVPVSNPVDLTAQGLVDPDLYRRALAALLDDPRFGAILLGIIQTDETTARLKFPPIIAALRELRPGKPVVFAGLDEGAAVPPDGLAALRDLGVPCFPSGERAVRALAAVARRSGRRIATAAAAPAAPAAPALARNLARNLAGVVPEYAAKAALAPLGVPFPEGRMATTLAEALRAAEVLGYPVVLKAQSAELSHKSDAGGVIVGLRDAQALAEGWERLAANVARHRPGLVLDGVLVERMGPRGVELILGGRNDPEWGPVVLVGFGGVQAEVLKDVRLLSPGMDEAAIAAEIMALRCAALLDGFRGAARCDVAAVARLAAALGRTLAGEPRIREIDLNPVVVYPAGEGALALDALMLVAPA
>NC_010511.1|WP_012333272.1|3894692_3895241_+|phage-tail-protein
MTALYVGQITLFAGNFAPRNWAFCNGQIMQIAQHPALFAILGNTYGGDGKTTFALPDLRGRVPLHPGQGAGLSSYVLGQHAGTETVTLGVQQIPAHSHKITGDATDGNVSSPDKAHLAQATVTIGGRPTPVLNHTSGTAAKPVSLADDTVQNAGGSQAHPNIQPYLALNFIIAVEGIYPARN
>NC_010511.1|WP_012333274.1|3895762_3896299_+|phage-tail-protein
MTEPFVGQIMLFAGNYAARGWAFCHGQLLPIAQYQALFAIIGTTYGGDGRVSFALPDLRGRVPVSAGQAPGLSNYVLGDKLGDEAVTLTQAQIPAHSHLVTVSDAQGTQVAAAGAFLANTSDANNRPLKTHNPAPAQSVVLNPGTIQSTGGSQPHENRQPTLVLNYLIALQGLFPARN
>NC_010511.1|WP_012333275.1|3896303_3896798_+|GNAT-family-N-acetyltransferase
MAAAHEAGPADVPVRRPERPEDAPFLRALFAAAQGTPLEGLPAPLRALLLDQGFAGQAATYRALYPQACHEIVEAGGVPVGRLVTARGAALTVVDVALLPPWQGRGLGTRLLGEVMAEAARLGLPVHLTVAQGNAGARRLYARLGFRPIAQTDLTLDLAWSPAP
>NC_010511.1|WP_012333276.1|3896794_3897382_+|aspartyl-beta-hydroxylase
MTPVPDRLRLPLRFDAAAMAAECAALGGTPWLRHFITRNYAGEWDVIPLRAPAGATHPVMMIAADPPAGDFADAPALAACPAIRAALAALPCPLASVRLMRLGPGSVIREHRDRDLAFEDGAVRLHVPLVTNPGVDFRLNGARVVMEPGSCWYLRLSDPHSVRNDGAAARIHLVIDAQVDAWVAALFRAAREAGG
>NC_010511.1|WP_012333277.1|3897378_3898593_+|sulfotransferase-family-protein
MSRDGFAALARRVAADAALAASLRPILDRDAFVAAACAAAAPAAEAVTPADVEAAMRANRHGWLMQSAPLALPGEVGPIENDDPDAFAGWTPFRTGWADGTLTVDWCHLGARRPTEPFFFETISREIGAPFNAAFQQRSRADALAARPPGLPPAGFIFHMARCGSTLCAQVLAADPSTLVLSEPGPLRGVLEAGHGGGLAPARVDAWLGGLVGALAARRFPDEARAVVKFMAADVLDLARIQRVFPDVPWLFLYREPLEILASQRRQAGADTMPGRIPASLLGLAEADLFALAPDLYQLRVMAALGRAALDGLARAPGRGLILRYDDLPEAILGRVAPHFGLWPDAAVLAAMRAAAARDAKAPGRAFRPDAEAKRREAAPWREAAAAITGEVVAALDAARGAGP
>NC_010511.1|WP_012333278.1|3898756_3899377_+|class-I-SAM-dependent-methyltransferase
MTDTAAIARAFETIYRADSWSHGSGPGSRPVNTIAYRAFLERFIAENRVATVTELGCGDWQFSRLIDWSGVTYTGFDVVESVITRNLARYWRDTVDFRLLTRIEDLPGGDLLLAKEVLQHLPLGVIRAYLPVIRSRYRFALITNTDKPEDGLNGEIEPGGYRPLRLDRPPFDLPGAVVLTYCPQTETGMWRNSVFLTFGTGGGNPA
>NC_010511.1|WP_012333279.1|3899373_3901359_+|glycosyltransferase
MTADRGICLCMIVKDEAPVIRRCLDSVRPLIDHWVVVDTGSTDGTQEIVRDALAGLPGALVERPWRDFAHNRSEALDLARPRGAYSLIIDADDTLEIPDGFVLPPLDADSYTLDIRFGAIAYRRPQLVRNALPWRYRGVLHEFLACEEARSSGHLPLTIRVSEDGRRRRDPATYRRDAAVLEQALAAETDPFLVARYTFYLAQTYRDCGAVQQAVEAYLRRATLGFWEEEVFVSLYQAGRLMEALRADPDEILAVYRRAGEVRPGRVEAAHAASRFCRGIGRNRQGHAIAKEALGRPAPADGLFVERWIYAYGLADEYAINAYWAGAMHDCIDGCLRALHSEMLPGPDRERILRNLRFAASALEQAPPRQPSPPLDPPAALRPLRSRLPEPAPRVLLAVLAKQKEPVLDLYLDCIEALDYPKSSIVLCVRTNNNTDRTGGMLRAWLDRVGGLYAGIVFDDADVPEPVQDLAVHEWTPQRFAVLGAIRQRSLALTLARDCAFYFVADADNFLIPSTLRDLVSLNLPIVAPMLREVKPGSRYANFHAAVDAQGYFAESRDYDALLERRILGVVEVPVVHCTYLVRADAIPLLRYEDGSGRHEYVVFSDHARRRGIPQYLDNRRCYGCLTLEDDDPEALAARLPAILAFLREVRAGDRPEPARA
>NC_010511.1|WP_012333280.1|3901395_3902265_-|alpha/beta-fold-hydrolase
MPPSDPDLTLLRLPEATLGLASAGPPDGPLTILLHGFPEFWYGWRHQIGPLAAAGLRVVALDQRGYGRSSKPAAVAAYRLERLAGDVLAVADAHGAARIRLVGHDWGGILGWWLAARRPERIARLAVLNAPHPDLLTAFLRRHPLQALRLGYFAGFQPPRLPEAALRAGRFLALREALRLTSRPGAFTPEDLARYETAWAEPGALTGMLNWYRAFPKRAPAPGRIRVPTLILWGRKDIALSPDLAETCLAACDEGEVAWFPEATHWLQHEEPEAVNAALAAFLTRPDGG
>NC_010511.1|WP_012333281.1|3902486_3904028_-|amidohydrolase-family-protein
MAELIVQAGWVVTGIRDRHTPIIVEDGAVLSRDGIIAAVGPAEALQRQAPRAELRRYPGHVMLPGFVNSHHHVGLTPLQLGSPDYALELWFASRLPARRIDLTLDTLYSAFEMVASGVTTVQHIQGWMAGGYEAIHAAATQTLNSYRSLGMRASYCYAVREQNRLVYEADEAFCARLPADLGAELAAHLRAQAMPFDDFLRLFDALREENEGQRLTRIQLAPANLHWCTDEGLVALDARARAAGAPMHMHLLETAYQKEYARRRTGKTALRHLHDLGVLGPHMTLGHGVWLTAEDIDIVAQTGTCLCHNCSSNFRLRSGLAPLNTWERKGITVGMGLDEAGLNDDRDMLQELRLALRVHRVPGMDDDDVPTPAQIVRMATESGAMTTAFGATIGRLEPGRFFDASLINWRRATYPFQDPDIPMLDALVQRAKIDSVDAVYIDGDLVYAEGRFTRIDRDAVLAEIAAILTRPRTPEEETRRRLGRAVFPHVKAFYDGYLPETPRSPFYAASSAV
>NC_010511.1|WP_012333282.1|3904040_3904847_-|carbon-nitrogen-hydrolase-family-protein
MTAALRVAALPVGPAGADPDAPWREVEAGAAAAARAGAALAVLPELTVLPCVAGDDPARWRHLAEPAAGPTVARMRALARRHRLALVFGMALAEDGAERPLNAALLAAPDGGVVRLAAKRRLPPPGPGDSVGEADHFRPGPAETRVVPVAGRRLAALVCYDRRFAESWDRLAGAADLVAVLVAGPAPQDPPGFFRRELAGHLRRCGLPAVAAARYGVEHGLGRPVRHDGESLVLGPDGTVLAASPPGAAAPALATLPPAPLRPSLPTA

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Crispr_ID: NC_010511_22

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_010511_22

3951374-3951483

Orphan

Consensus_repeat	Method
CGAAGCCGAAATCCGCTTGGCGAAGCAATCCGTCGGATTTCG	CRISPRCasFinder

1 spacers

The CRISPR arrays of NC_010511_22

>merge|NC_010511|22|3951374-3951483|CRISPRCasFinder
CGAAGCCGAAATCCGCTTGGCGAAGCAATCCGTCGGATTTCGTCTGACAAGCCCGCGCGGCGCGTGAGCGAAGCCGAAATCCGCATGGCGAAGCAATCCGTCGGATTTCG

>NC_010511|22|22|3951374-3951483|CRISPRCasFinder
CGAAGCCGAAATCCGCTTGGCGAAGCAATCCGTCGGATTTCG	TCTGACAAGCCCGCGCGGCGCGTGAG
CGAAGCCGAAATCCGCATGGCGAAGCAATCCGTCGGATTTCG

Protein	Signature genes	Signature genes Name	Protein_function
NC_010511.1\|WP_012333322.1\|3951531_3952008_+\|NifX-associated-nitrogen-fixation-protein	unknown	unknown	gnl\|CDD\|131981
NC_010511.1\|WP_012333318.1\|3946337_3947876_+\|nitrogenase-molybdenum-iron-protein-subunit-beta	unknown	unknown	gnl\|CDD\|130353
NC_010511.1\|WP_012333319.1\|3947947_3949459_+\|nitrogenase-iron-molybdenum-cofactor-biosynthesis-protein-NifE	unknown	unknown	gnl\|CDD\|184699
NC_010511.1\|WP_012333328.1\|3955548_3956913_+\|dicarboxylate/amino-acid:cation-symporter	unknown	unknown	gnl\|CDD\|234968
NC_010511.1\|WP_012333329.1\|3956986_3959272_+\|NADP-dependent-malic-enzyme	unknown	unknown	gnl\|CDD\|183799
NC_010511.1\|WP_012333324.1\|3952269_3952584_+\|ferredoxin-III,-nif-specific	unknown	unknown	gnl\|CDD\|274356
NC_010511.1\|WP_150108850.1\|3960236_3961538_+\|MFS-transporter	unknown	unknown	gnl\|CDD\|340927
NC_010511.1\|WP_012333330.1\|3959540_3960167_+\|RraA-family-protein	unknown	unknown	gnl\|CDD\|180465
NC_010511.1\|WP_012333323.1\|3952019_3952217_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|377451
NC_010511.1\|WP_012333327.1\|3953753_3954551_+\|SDR-family-oxidoreductase	unknown	unknown	gnl\|CDD\|212491
NC_010511.1\|WP_012333325.1\|3952587_3953241_+\|nitrogen-fixation-protein-NifQ	unknown	unknown	gnl\|CDD\|377416
NC_010511.1\|WP_012333315.1\|3942005_3942848_+\|ModD-protein	unknown	unknown	gnl\|CDD\|238807
NC_010511.1\|WP_012333316.1\|3943665_3944565_+\|nitrogenase-iron-protein	unknown	unknown	gnl\|CDD\|183906
NC_010511.1\|WP_012333326.1\|3953387_3953672_+\|(2Fe-2S)-binding-protein	unknown	unknown	gnl\|CDD\|377304
NC_010511.1\|WP_012333320.1\|3949469_3950852_+\|nitrogenase-iron-molybdenum-cofactor-biosynthesis-protein-NifN	unknown	unknown	gnl\|CDD\|237722
NC_010511.1\|WP_012333312.1\|3939678_3940209_-\|alkyl-hydroperoxide-reductase-AhpD	unknown	unknown	gnl\|CDD\|129859
NC_010511.1\|WP_012333313.1\|3940220_3940775_-\|peroxiredoxin	unknown	unknown	gnl\|CDD\|239313
NC_010511.1\|WP_012333317.1\|3944719_3946237_+\|nitrogenase-molybdenum-iron-protein-alpha-chain	unknown	unknown	gnl\|CDD\|162284
NC_010511.1\|WP_043701332.1\|3950820_3951315_+\|nitrogen-fixation-protein-NifX	unknown	unknown	gnl\|CDD\|131711
NC_010511.1\|WP_012333314.1\|3941098_3941986_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|132352

Protein	Function_ID	Function_description	E-value
NC_010511.1\|WP_012333322.1\|3951531_3952008_+\|NifX-associated-nitrogen-fixation-protein	gnl\|CDD\|131981	TIGR02935, UPF0460_protein_in_nifX_3'region, probable nitrogen fixation protein. Members of this protein family, called DUF269 by pfam03270, are strictly limited to nitrogen-fixing species, although not universal among them. The gene typically is found next to the nifX gene (see TIGRFAMs model TIGR02663). [Central intermediary metabolism, Nitrogen fixation].	5.44841e-78
NC_010511.1\|WP_012333318.1\|3946337_3947876_+\|nitrogenase-molybdenum-iron-protein-subunit-beta	gnl\|CDD\|130353	TIGR01286, Nitrogenase_molybdenum-iron_protein_beta_chain, nitrogenase molybdenum-iron protein beta chain. This model represents the majority of known sequences of the nitrogenase molybdenum-iron protein beta subunit. A distinct clade in a phylogenetic tree contains molybdenum-iron, vanadium-iron, and iron-iron forms of nitrogenase beta subunit and is excluded from this model. Nitrogenase, also called dinitrogenase, is responsible for nitrogen fixation. Note: the trusted cutoff score has recently been lowered to include an additional family in which the beta subunit is shorter by about 50 amino acids at the N-terminus. In species with the shorter form of the beta subunit, the alpha subunit has a novel insert of similar length. [Central intermediary metabolism, Nitrogen fixation].	0
NC_010511.1\|WP_012333319.1\|3947947_3949459_+\|nitrogenase-iron-molybdenum-cofactor-biosynthesis-protein-NifE	gnl\|CDD\|184699	PRK14478, PRK14478, nitrogenase molybdenum-cofactor biosynthesis protein NifE; Provisional.	0
NC_010511.1\|WP_012333328.1\|3955548_3956913_+\|dicarboxylate/amino-acid:cation-symporter	gnl\|CDD\|234968	PRK01663, PRK01663, C4-dicarboxylate transporter DctA; Reviewed.	0
NC_010511.1\|WP_012333329.1\|3956986_3959272_+\|NADP-dependent-malic-enzyme	gnl\|CDD\|183799	PRK12862, PRK12862, malic enzyme; Reviewed.	0
NC_010511.1\|WP_012333324.1\|3952269_3952584_+\|ferredoxin-III,-nif-specific	gnl\|CDD\|274356	TIGR02936, fdxN_nitrog, ferredoxin III, nif-specific. Members of this family are homodimeric ferredoxins from nitrogen fixation regions of many nitrogen-fixing bacteria. As characterized in Rhodobacter capsulatus, these proteins are homodimeric, with two 4Fe-4S clusters bound per monomer. Although nif-specific, this protein family is not usiveral, as other nitrogenase systems may substitute flavodoxins, or different types of ferredoxin. [Central intermediary metabolism, Nitrogen fixation].	5.02367e-40
NC_010511.1\|WP_150108850.1\|3960236_3961538_+\|MFS-transporter	gnl\|CDD\|340927	cd17369, MFS_ShiA_like, Shikimate transporter and similar proteins of the Major Facilitator Superfamily. This subfamily is composed of Escherichia coli shikimate transporter (ShiA), inner membrane metabolite transport protein YhjE, and other putative metabolite transporters. ShiA is involved in the uptake of shikimate, an aromatic compound involved in siderophore biosynthesis. It has been suggested that YhjE may mediate the uptake of osmoprotectants. The ShiA-like subfamily belongs to the Metazoan Synaptic Vesicle Glycoprotein 2 (SV2) and related small molecule transporter family (SV2-like) of the Major Facilitator Superfamily (MFS) of membrane transport proteins. MFS proteins are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	5.96935e-107
NC_010511.1\|WP_012333330.1\|3959540_3960167_+\|RraA-family-protein	gnl\|CDD\|180465	PRK06201, PRK06201, hypothetical protein; Validated.	2.35634e-90
NC_010511.1\|WP_012333323.1\|3952019_3952217_+\|hypothetical-protein	gnl\|CDD\|377451	pfam05082, Rop-like, Rop-like. This family contains several uncharacterized bacterial proteins. These proteins are found in nitrogen fixation operons so are likely to play some role in this process. They consist of two alpha helices which are joined by a four residue linker. The helices form an antiparallel bundle and cross towards their termini. They are likely to form a rod-like dimer. They have structural similarity to the regulatory protein Rop, pfam01815.	1.04446e-23
NC_010511.1\|WP_012333327.1\|3953753_3954551_+\|SDR-family-oxidoreductase	gnl\|CDD\|212491	cd05233, SDR_c, classical (c) SDRs. SDRs are a functionally diverse family of oxidoreductases that have a single domain with a structurally conserved Rossmann fold (alpha/beta folding pattern with a central beta-sheet), an NAD(P)(H)-binding region, and a structurally diverse C-terminal region. Classical SDRs are typically about 250 residues long, while extended SDRs are approximately 350 residues. Sequence identity between different SDR enzymes are typically in the 15-30% range, but the enzymes share the Rossmann fold NAD-binding motif and characteristic NAD-binding and catalytic sequence patterns. These enzymes catalyze a wide range of activities including the metabolism of steroids, cofactors, carbohydrates, lipids, aromatic compounds, and amino acids, and act in redox sensing. Classical SDRs have an TGXXX[AG]XG cofactor binding motif and a YXXXK active site motif, with the Tyr residue of the active site motif serving as a critical catalytic residue (Tyr-151, human prostaglandin dehydrogenase (PGDH) numbering). In addition to the Tyr and Lys, there is often an upstream Ser (Ser-138, PGDH numbering) and/or an Asn (Asn-107, PGDH numbering) contributing to the active site; while substrate binding is in the C-terminal region, which determines specificity. The standard reaction mechanism is a 4-pro-S hydride transfer and proton relay involving the conserved Tyr and Lys, a water molecule stabilized by Asn, and nicotinamide. Extended SDRs have additional elements in the C-terminal region, and typically have a TGXXGXXG cofactor binding motif. Complex (multidomain) SDRs such as ketoreductase domains of fatty acid synthase have a GGXGXXG NAD(P)-binding motif and an altered active site motif (YXXXN). Fungal type ketoacyl reductases have a TGXXXGX(1-2)G NAD(P)-binding motif. Some atypical SDRs have lost catalytic activity and/or have an unusual NAD(P)-binding motif and missing or unusual active site residues. Reactions catalyzed within the SDR family include isomerization, decarboxylation, epimerization, C=N bond reduction, dehydratase activity, dehalogenation, Enoyl-CoA reduction, and carbonyl-alcohol oxidoreduction.	5.05353e-62
NC_010511.1\|WP_012333325.1\|3952587_3953241_+\|nitrogen-fixation-protein-NifQ	gnl\|CDD\|377416	pfam04891, NifQ, NifQ. NifQ is involved in early stages of the biosynthesis of the iron-molybdenum cofactor (FeMo-co), which is an integral part of the active site of dinitrogenase. The conserved C-terminal cysteine residues may be involved in metal binding.	9.89422e-70
NC_010511.1\|WP_012333315.1\|3942005_3942848_+\|ModD-protein	gnl\|CDD\|238807	cd01573, modD_like, ModD; Quinolinate phosphoribosyl transferase (QAPRTase or QPRTase) present in some modABC operons in bacteria, which are involved in molybdate transport. In general, QPRTases are part of the de novo synthesis pathway of NAD in both prokaryotes and eukaryotes. They catalyse the reaction of quinolinic acid (QA) with 5-phosphoribosyl-1-pyrophosphate (PRPP) in the presence of Mg2+ to produce nicotinic acid mononucleotide (NAMN), pyrophosphate and carbon dioxide.	1.50622e-107
NC_010511.1\|WP_012333316.1\|3943665_3944565_+\|nitrogenase-iron-protein	gnl\|CDD\|183906	PRK13234, nifH, nitrogenase reductase; Reviewed.	0
NC_010511.1\|WP_012333326.1\|3953387_3953672_+\|(2Fe-2S)-binding-protein	gnl\|CDD\|377304	pfam04324, Fer2_BFD, BFD-like [2Fe-2S] binding domain. The two Fe ions are each coordinated by two conserved cysteine residues. This domain occurs alone in small proteins such as Bacterioferritin-associated ferredoxin (BFD). The function of BFD is not known, but it may may be a general redox and/or regulatory component involved in the iron storage or mobilisation functions of bacterioferritin in bacteria. This domain is also found in nitrate reductase proteins in association with Nitrite and sulphite reductase 4Fe-4S domain (pfam01077), Nitrite/Sulfite reductase ferredoxin-like half domain (pfam03460) and Pyridine nucleotide-disulphide oxidoreductase (pfam00070). It is also found in NifU nitrogen fixation proteins, in association with NifU-like N terminal domain (pfam01592) and NifU-like domain (pfam01106).	0.000110581
NC_010511.1\|WP_012333320.1\|3949469_3950852_+\|nitrogenase-iron-molybdenum-cofactor-biosynthesis-protein-NifN	gnl\|CDD\|237722	PRK14476, PRK14476, nitrogenase molybdenum-cofactor biosynthesis protein NifN; Provisional.	0
NC_010511.1\|WP_012333312.1\|3939678_3940209_-\|alkyl-hydroperoxide-reductase-AhpD	gnl\|CDD\|129859	TIGR00777, AhpD_protein., alkylhydroperoxidase, AhpD family. Members of this family are alkylhydroperoxidases, which catalyze the reduction of peroxides to their corresponding alcohols via oxidation of cysteine residues. In these alkylhydroperoxidases, the cysteines are located in a conserved -CXXC- motif located towards the COOH terminus. In Mycobacterium tuberculosis, two non-homologous alkylhydroperoxidases, AhpD and AhpC, are found in the same operon. [Cellular processes, Detoxification].	6.51811e-52
NC_010511.1\|WP_012333313.1\|3940220_3940775_-\|peroxiredoxin	gnl\|CDD\|239313	cd03015, PRX_Typ2cys, Peroxiredoxin (PRX) family, Typical 2-Cys PRX subfamily; PRXs are thiol-specific antioxidant (TSA) proteins, which confer a protective role in cells through its peroxidase activity by reducing hydrogen peroxide, peroxynitrite, and organic hydroperoxides. The functional unit of typical 2-cys PRX is a homodimer. A unique intermolecular redox-active disulfide center is utilized for its activity. Upon reaction with peroxides, its peroxidatic cysteine is oxidized into a sulfenic acid intermediate which is resolved by bonding with the resolving cysteine from the other subunit of the homodimer. This intermolecular disulfide bond is then reduced by thioredoxin, tryparedoxin or AhpF. Typical 2-cys PRXs, like 1-cys PRXs, form decamers which are stabilized by reduction of the active site cysteine. Typical 2-cys PRX interacts through beta strands at one edge of the monomer (B-type interface) to form the functional homodimer, and uses an A-type interface (similar to the dimeric interface in atypical 2-cys PRX and PRX5) at the opposite end of the monomer to form the stable decameric (pentamer of dimers) structure.	6.08076e-67
NC_010511.1\|WP_012333317.1\|3944719_3946237_+\|nitrogenase-molybdenum-iron-protein-alpha-chain	gnl\|CDD\|162284	TIGR01282, Nitrogenase_molybdenum-iron_protein_alpha_chain, nitrogenase molybdenum-iron protein alpha chain. Nitrogenase consists of alpha (NifD) and beta (NifK) subunits of the molybdenum-iron protein and an ATP-binding iron-sulfur protein (NifH). This model describes a large clade of NifD proteins, but excludes a lineage that contains putative NifD and NifD homologs from species with vanadium-dependent nitrogenases. [Central intermediary metabolism, Nitrogen fixation].	0
NC_010511.1\|WP_043701332.1\|3950820_3951315_+\|nitrogen-fixation-protein-NifX	gnl\|CDD\|131711	TIGR02663, Protein_NifX, nitrogen fixation protein NifX. Members of this family are NifX proteins encoded within operons for nitrogen fixation in a number of bacteria. NifX, NafY, and the C-terminal region of NifB all belong to the pfam02579 and are involved in MoFe cofactor biosynthesis. NifX is a nitrogenase accessory protein with a role in expression of the MoFe cofactor. [Biosynthesis of cofactors, prosthetic groups, and carriers, Other, Central intermediary metabolism, Nitrogen fixation].	2.25573e-63
NC_010511.1\|WP_012333314.1\|3941098_3941986_+\|hypothetical-protein	gnl\|CDD\|132352	TIGR03309, matur_yqeB, selenium-dependent molybdenum hydroxylase system protein, YqeB family. Members of this protein family are probable accessory proteins for the biosynthesis of enzymes with labile selenium-containing centers, different from selenocysteine-containing proteins.	5.30018e-43

>NC_010511.1|WP_043701332.1|3950820_3951315_+|nitrogen-fixation-protein-NifX
MTALRRLRLVESEEPAEQAAGPALRVAIATQDLKSLNAHFGSARRFALYDVTVRGWSFVEAVTFEEVSDEGGRHRTDGDDRITPKVEALRGCHLLFCLAIGGPSAAKVVTAKIHPIKIAQAQPIEAVLERTRAMLAGAPPPWLRKVLAASGATAPEPSFADDED
>NC_010511.1|WP_012333320.1|3949469_3950852_+|nitrogenase-iron-molybdenum-cofactor-biosynthesis-protein-NifN
MNPVTPLAKAVATNPLKSSQPLGAALAFLGIEGAMPLFHGSQGCTSFALVLLVRHFKETVPLQTTAMDEVATVLGGADHLEEAILTLKTRTGPSLIGICTTALVETRGEDFSGDLALIRGRHAETLGETELVLAQTPDFAGAMEEGWAKAVCATIAQVVPEAESRVAALNRINILPGQHHTVADVEFLRESALAFGLEPVILPDIAGSLDGTVPARWIPTSYGGTPVAAIRGMGRALHTIALAEHVRGAAALLEARTGVPFTVLDTLTGLKAADRYVALLASLSGKPVPAALRRRRSQLEDALLDGHFHIGGLRVAIAAEPDLLYGLASFFAGLGATVALAVTTTGDSPILARVPAETVVVGDLGDLEARASGCDLLVTHSHGRQASERLGIPLMRVGFPIFDRLGSPHRLSIGHEGTRDLIFEVANLVQANRREPTPQSLNPFRDRGESHDGLAQIAAR
>NC_010511.1|WP_012333319.1|3947947_3949459_+|nitrogenase-iron-molybdenum-cofactor-biosynthesis-protein-NifE
MLKDKIADVFNEPGCEKNQAKGAKERKKGCTKPLTPGAAAGGCAFDGAKIVLQPITDVAHLIHAPLACEGNSWDNRGAGSSGSDLWRRSFTTDLTELDVVMGQGERKLYRAVREIARTYAPPAIFVYSTCVTALIGDDIEAVCAKASETCGLPVIPVNAPGFVGSKNLGNKLAGEALLDHVIGTVEPDDVGPTDINILGEFNLAGEFWAVRPLFERLGIRIRACIPGDARYREVAAAHTARATMMECSTALINLARKMEERWGIPFFEGSFYGISDTSDALRQTARLLVGRGAPSDLLDRTEALIAEEEARAWARLEAFRPRLQGKRVLLNTGGVKSWSVVAALMEIGVEIVGTSVKKSTAEDKERIKQLLKDENHMFESMAPRDLYAKLASHEADIMLSGGRTQFIALKAKMPWLDINQERHVAYAGYDGMVELVRRIDLALSNPIWADLRDPAPWDAEGRLTAAGAAPRAEPGRDPAADPTFLAHHRRKFAGAGADDMAEC
>NC_010511.1|WP_012333318.1|3946337_3947876_+|nitrogenase-molybdenum-iron-protein-subunit-beta
MPQSADRVLDHAPLFRQPEYQEMFARKREQFECPASGEAVEAQRDYARTWEYREKNLAREALVVNPAKACQPLGAVFAAAGFERTMSFVHGSQGCVAYYRSHLSRHFKEPSSAVSSSMTEDAAVFGGLNNMIDGLANTYSLYDPKMIAVSTTCMAEVIGDDLHAFIQNAKNKGSVPQDYDVPFAHTPAFVGSHVDGYDNMIKGVLEHFWKGRTRSAGEGLNLIPGFDGFCVGNNRELKRLLDLIGVSYTLIQDASDTYDTPSDGEFRMYSGGTRLEDVAAALNARATLSLQKYCTRKTLDYAAEQGQETHSFHYPLGVRGTDELLLKISELSGRPIPEAITMERGRLIDAMADSQSWLHGKKYAIFGDPDVVYGLARFVMETGGEPIHCLATNGTKAWEEEMQALLASSPFGASGQVWAGKDLWHLRSLLFTEPVDFVLGNSYAKYLERDTGTPLIRTAFPIFDRHHHHRFPVMGYQGGLRLLTTILDKIFDKLDQDTIDPAKTDYSFDLTR
>NC_010511.1|WP_012333317.1|3944719_3946237_+|nitrogenase-molybdenum-iron-protein-alpha-chain
MSLDYENDGALHEKIIEDVLAAYPDKFAKRRRKHLSVATPAGAEETAPAEETLLTECDVKSNIKSIPGVMTIRGCAYAGSKGVVWGPVKDMVHISHGPVGCGQYSWSQRRNYYIGTTGIDTFVTMQFTSDFQEKDIVFGGDKKLDKVISEIESLFPLNHGVTIQSECPIGLIGDDIEAVARKKKKEIGKTVVPVRCEGFRGVSQSLGHHIANDAIRDWVFEKQDGEIAFEGTPYDVNVIGDYNIGGDAWASRILLEEMGLRIVGNWSGDATLAEIERAPKAKLNLIHCYRSMNYICRYMEEKYAIPWMEYNFFGPSQIAASLRKIAKHFGPEIEEKAEAVIAKYQPLVDAVIAKYGPRLKGKSVMLYVGGLRPRHVITAYEDLGMEIAGTGYEFAHNDDYQRTGHYVKNGTLIYDDVTGYELEKFIEKIRPDLVGSGIKEKYPVQKMGIPFRQMHSWDYSGPYHGYDGFAIFARDMDLAINNPVWGLFDAPWKAKPAPAFLDAAE
>NC_010511.1|WP_012333316.1|3943665_3944565_+|nitrogenase-iron-protein
MAGLRQIAFYGKGGIGKSTTSQNTLAALVEMGQKILIVGCDPKADSTRLILNAKAQDTVLSLAAEAGSVEDLELEDVLKIGYRGIKCVESGGPEPGVGCAGRGVITSINFLEENGAYEDVDYVSYDVLGDVVCGGFAMPIRENKAQEIYIVMSGEMMALYAANNIAKGILKYAHSGGVRLGGLICNERQTDRELDLAEALAKRLNSQLIHFVPRDNIVQHAELRRQTVIEYAPASAQAAEYRKLAQKVHENGGKGTIPTPITMEELEQMLLDFGIMKTEEQQLAELAAKEAAKAAAAVH
>NC_010511.1|WP_012333315.1|3942005_3942848_+|ModD-protein
MSSLWWSDALIDRWLAEDVPHGDLTTRALGIGERPARMRFSLRAAGTVCGTEAALALVRRAGGEGAVRAASGSRVPAGGVLLDATGPAGALHESWKVAQTLIEALSGIATATAAIVDAARAVAPAIAVVTTRKTLPGAKGPMIAAIRAGGAEPHRLGLSETLLVFPEHRAFLPDPVAALTALRRAAPEKAIVVEVTGLEEARALLAAGPDILQCEKLPPETVAAVKALARAAGGVTRVAAAGGVTAANAAAYAAAGADILVTSAPYWAKPADVKVAIEAA
>NC_010511.1|WP_012333314.1|3941098_3941986_+|hypothetical-protein
MQTVNSFAPAGRAPVAIVLGTNDVATAVAHALHGAGYGVVLSRDAAHPVLRRRMAFDEALETGRVEIEGLEAVAADTLVQIMMAFLDRRFVCVTTMELGDLVCLGLIDVLVDARMRMRHLAADIRPYARLTIGLGPGFTSGRTVDAAIETAPEAVGIVPPAGSTLAAHGRSALLGGAGRERFARAPRDGLWRTRAEIGAAVRAGESLGTCAGIAVAAPLSGRLRGLVRDATDLRAGTKVAEVDPRPDGEASWLGIADRPRRIAAATLDAIRTLDDLCASGQDRAGARGGPRIWHS
>NC_010511.1|WP_012333313.1|3940220_3940775_-|peroxiredoxin
MLGIGDTLPAFEVVGVKPGFNHHQENGVSAFEALTRDSFPGKWKVIFFYPKDFTFVCPTEIAEFAKLAPDFEDRDAVVLGGSSDNEHVKLAWRRDHKDLDRLPIWSFADPKGSLIDGLGVRSPEGVAYRVTVVVDPANVIQHVYATNLNVGRAPKDTLRVLDALQTDELCPCNREVGGGVLKAA
>NC_010511.1|WP_012333312.1|3939678_3940209_-|alkyl-hydroperoxide-reductase-AhpD
MTLDALLQSLPPYAKDVRLNFSSLGREETLTAQQRDGLLVACGLASRNPDLARALEAEAAPRLSPAALAAAKAAATVMAMNNVYYRFTHLASNPAYATRPAKLRMSSIGNPGVARADFELWSLAVSAINGCGRCIDAHEQVLREAGVGEEAIQAAVRVAAVVASLAVALESVRAAA
>NC_010511.1|WP_012333322.1|3951531_3952008_+|NifX-associated-nitrogen-fixation-protein
MSETATLERAPEEAALATPFLTALVRLLRAQDSYGAWEKKPDAQLLRDFIVSKEQRRQIPIMGDPDPDVLWRVELFYTAVGLAVEARAGLIASPMMKMSHEGFGRVLLTAGRLIVLNKYLRDVHRFGFESLAKLAEAGGRAIDEAAAMIAAHPDVARI
>NC_010511.1|WP_012333323.1|3952019_3952217_+|hypothetical-protein
MSDIETLKAEIKKLSSRSVTAKMNLHDLSEDLPTNWQSILRVAQETYDAFQALDAARRALKAAEA
>NC_010511.1|WP_012333324.1|3952269_3952584_+|ferredoxin-III,-nif-specific
MAFTTRDGRAWMPDYLVAIDAKTCIGCGRCYKVCSRDVMHLFGVGAENALLGRVGDEDDDEFDGKLVRKVMVVDEAGACIGCGACARVCPKACQTHVPADRIAA
>NC_010511.1|WP_012333325.1|3952587_3953241_+|nitrogen-fixation-protein-NifQ
MAAPGYAALMAGQEAARPSADPFDAHLFACALALCAAEAAHRGESLAARLGLGPEDLAALEARFFAPGALAPGTLAPGTLARSGTARPDPGEEEAMVRDLLLAHRAGRGPEEAWLAAIVARRAMEPDHLWQDLGLQARSELSRLMARHFPALAAGNDRNMKWKKYLYRRLCEAEGFVLCTAPSCGVCADFGSCFGDESGESRMAQRRRAADHALAAP
>NC_010511.1|WP_012333326.1|3953387_3953672_+|(2Fe-2S)-binding-protein
MIVCSCNVLSDTAVRACAADSALTPAGVFRALGCRIRCGRCAKTIRAILTNREVGPGALPSCDGRCCAARDTAAWINQGSLAAMAAATAQAPPR
>NC_010511.1|WP_012333327.1|3953753_3954551_+|SDR-family-oxidoreductase
MSTSTPCSSAGAERGARAAERGAGRTLLLTGASRGIGHATVKIFAEAGWRVITCARRPFDPNCPWESGRIDHVPVDLADPAATGRAVARVKELIGDGPLHALVNNAGISPKTPAGGRLSSVDTPLQTWMDVFHVNFLAPVILARGLLDNLVAAGGSIVNLTSIAGTRVHPFAGAAYATSKAALSCLTREMAFDFAPYGVRVNAIAPGEIRTEILSAETEAHLAPTIPMRRIGTPAEVASVIYFLCSQHASYVTGEEVQINGGQHV
>NC_010511.1|WP_012333328.1|3955548_3956913_+|dicarboxylate/amino-acid:cation-symporter
MTAAISETDHQTVKWYSHLYVQVLGAITVGVVLGHFYPQIGEQMKPLGDAFIKAIKMIIAPIIFFAVVHGIASMGDMKKVGRVGLKALIYFEVVTTLALIIGLVVVNLWKPGVGINLDLSTVDAKSIASFTAEAKDQSTVHFLMEIIPSTVVGAFAKGEILQVLFFAILFAFGLQALGERGGGVLRLIDTVGHVFFKIVGYIMKAAPIGAFGAMAFTIGKYGISTLLSLGNFMLSFYTTCLLFIFVVLGSIAALHGFSILKFIRYIKEELLIVLGTSSSESVLPRMIAKMENLGADKSVVGLVVPTGYSFNLDGTCIYLTMAVIFLAQATNIDLTVWQELGIIGVLLLTSKGAAGVTGSGFIVLAATLASVGTIPVASIALILGVDRFMSEARALTNVIGNGLATIVVAKWEGVLDEEVLRRRLNAETDAEADEPEDVAIADDAKSGPPQPITA
>NC_010511.1|WP_012333329.1|3956986_3959272_+|NADP-dependent-malic-enzyme
MADNVSEELEHAALAYHCYPYPGKLAVVPTKPLGTQRDLALAYSPGVAIPCEEIAADPDKAADYTSRQNLVAVVSNGTAVLGLGAIGALASKPVMEGKAVLFKKFAGIDVFDIEVDERDVDRMVDVVCSLEPTFGGINLEDIKAPECFEIEEKCKTRMKIPVFHDDQHGTAIIVSAAVLNSLELSGKKIESIKVVTSGAGAAALATLNLLVSLGVPREHIWVTDIEGVVYAGRNELMDRWKEVYAQTTDKRTLAEVIDGADVVIGLSAAGVIKPEMLKVMKPNPLIMALANPTPEIMPELAREARPDALICTGRSDFPNQVNNVLCFPYIFRGALDVGASTINEEMKSAAVRAIAALAREAPSDVVARAYGGEARPFGAESLIPSPFDPRLILRIAPAVAKAAMDTGVARRPVADIEAYTESLGRFVFRSGFVMKPIFTAARASPRRVAYAEGEDERVLRAVHAVVEERIARPILIGRPAVIEMRLKRFGLSIKAGRDFDFINPEDDPRYRDYVATLVERAGRKGITPDAARTLVRTNATIIGSLALMRGDADALLCGLEGRFRSNLDHITNIVGYGPGMHQLAALSLMITSQGPLFLAHTHVRPNPTAEEIAEMTCACAGHVRRFGITPKVALLSYSDFGSGDTESAVKMRKALALVQELAPDLEADGEMAADTALSQLIRDRVNPGSKLKGEANLLILPNLDAANIAFQLVRVLADALPVGPILIGPSKPVHILTPSVTARGVTNMTAVAVIEAQSQVN
>NC_010511.1|WP_012333330.1|3959540_3960167_+|RraA-family-protein
MKTIEQAKSLELAELFREAPVAVISDNLDRLPGFLDMRPYHRGAKLVGPARTVRTRPGDNLMIHKVLELVQPGEVIVVAGEGDTTRALIGEIIVRIAQMRGVAGFVVDGAIRDLGTISAGTFPCFARGVIHRGPYKDGPGEIDVPIAMSGGTVVSPGDIIVGDEDGVVSFPQSIARDLSGKVEAHLAKEAAILKSIANSTYTGAYSKS
>NC_010511.1|WP_150108850.1|3960236_3961538_+|MFS-transporter
MSVAMHAGGIKEKAKQATGAAVFGTFIEYYDFSVYGYVAATLSLVFFPAGDAVANLLNTLAVFGLAFLVRPIGAWYFGQLGDRRGRRTSLIATITLMGVASALTGLLPSYQTIGIVAPVLLVLMRLLQGFSTGGEIGGAASYIREWAAPDRRALYISFLPSVAQLGKGLAAALGGLMAAMLTRESMIEWGWRIPFLLAGPLAVLTIWMRLSIEDSPEFAALSASHKTTKAPLASLFQQYPTALAKVMLISAVQNIGTYIGTVFVSVYFSEVLGFSKAEAATVVLLAVILASFLIPLAGMIGNRVGGKTLLLIAYTAYLLLTLPEFMLMNQNNIVLALLGLSIGIIPYALCQAGTYATMPEMFPTQIRHTGVAFGHSVGAVVGGGGGPYFAAWLISVTGNTYMPAYILMGAGLVGLVVVGLTVRRNVGGTHLYA

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Crispr_ID: NC_010511_23

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_010511_23

3970270-3970366

Orphan

Consensus_repeat	Method
TCGCTCAAGCGCCGCGCGGGCTTGTCAT	CRISPRCasFinder

1 spacers

The CRISPR arrays of NC_010511_23

>merge|NC_010511|23|3970270-3970366|CRISPRCasFinder
TCGCTCAAGCGCCGCGCGGGCTTGTCATCCCAAACCCGCTTGATCCCTTCGGGATGGCGGATTGGGGCTTCGCTCAAGCGCCGCGCGGGCTTGTCAT

>NC_010511|23|23|3970270-3970366|CRISPRCasFinder
TCGCTCAAGCGCCGCGCGGGCTTGTCAT	CCCAAACCCGCTTGATCCCTTCGGGATGGCGGATTGGGGCT
TCGCTCAAGCGCCGCGCGGGCTTGTCAT

Protein	Signature genes	Signature genes Name	Protein_function
NC_010511.1\|WP_012333339.1\|3975285_3976935_+\|DAK2-domain-containing-protein	unknown	unknown	gnl\|CDD\|274097
NC_010511.1\|WP_043701341.1\|3980825_3981479_+\|Spy/CpxP-family-protein-refolding-chaperone	unknown	unknown	gnl\|CDD\|197366
NC_010511.1\|WP_012333340.1\|3977045_3977999_+\|glyoxylate/hydroxypyruvate-reductase-A	unknown	unknown	gnl\|CDD\|240641
NC_010511.1\|WP_012333330.1\|3959540_3960167_+\|RraA-family-protein	unknown	unknown	gnl\|CDD\|180465
NC_010511.1\|WP_150108850.1\|3960236_3961538_+\|MFS-transporter	unknown	unknown	gnl\|CDD\|340927
NC_010511.1\|WP_012333328.1\|3955548_3956913_+\|dicarboxylate/amino-acid:cation-symporter	unknown	unknown	gnl\|CDD\|234968
NC_010511.1\|WP_012333332.1\|3962913_3964161_-\|pentapeptide-repeat-containing-protein	unknown	unknown	gnl\|CDD\|224276
NC_010511.1\|WP_012333333.1\|3964157_3966101_-\|AI-2E-family-transporter	unknown	unknown	gnl\|CDD\|223701
NC_010511.1\|WP_012333334.1\|3966097_3966475_-\|response-regulator	unknown	unknown	gnl\|CDD\|381100
NC_010511.1\|WP_043701338.1\|3970444_3971437_-\|hypothetical-protein	unknown	unknown	unknown
NC_010511.1\|WP_012333336.1\|3969065_3970229_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|270238
NC_010511.1\|WP_012333344.1\|3981495_3982188_+\|response-regulator-transcription-factor	unknown	unknown	gnl\|CDD\|223816
NC_010511.1\|WP_012333329.1\|3956986_3959272_+\|NADP-dependent-malic-enzyme	unknown	unknown	gnl\|CDD\|183799
NC_010511.1\|WP_012333327.1\|3953753_3954551_+\|SDR-family-oxidoreductase	unknown	unknown	gnl\|CDD\|212491
NC_010511.1\|WP_012333346.1\|3983462_3984272_-\|SDR-family-oxidoreductase	unknown	unknown	gnl\|CDD\|223377
NC_010511.1\|WP_012333342.1\|3979424_3980486_+\|plasmid-partitioning-protein-RepB	unknown	unknown	gnl\|CDD\|274586
NC_010511.1\|WP_012333345.1\|3982184_3983429_+\|HAMP-domain-containing-protein	unknown	unknown	gnl\|CDD\|236724
NC_010511.1\|WP_012333335.1\|3966551_3968819_-\|glycogen-debranching-protein-GlgX	unknown	unknown	gnl\|CDD\|131155
NC_010511.1\|WP_012333338.1\|3972124_3975079_-\|response-regulator	unknown	unknown	gnl\|CDD\|236848
NC_010511.1\|WP_012333341.1\|3978210_3979428_+\|plasmid-partitioning-protein-RepA	unknown	unknown	gnl\|CDD\|274585

Protein	Function_ID	Function_description	E-value
NC_010511.1\|WP_012333339.1\|3975285_3976935_+\|DAK2-domain-containing-protein	gnl\|CDD\|274097	TIGR02361, Dihydroxyacetone_kinase_1, dihydroxyacetone kinase, ATP-dependent. This family consists of examples of the form of dihydroxyacetone kinase (also called glycerone kinase) that uses ATP (2.7.1.29) as the phosphate donor, rather than a phosphoprotein as in E. coli. This form is composed of a single chain with separable domains homologous to the K and L subunits of the E. coli enzyme, and is found in yeasts and other eukaryotes and in some bacteria, including Citrobacter freundii. The member from tomato has been shown to phosphorylate dihydroxyacetone, 3,4-dihydroxy-2-butanone, and some other aldoses and ketoses ().	1.23572e-158
NC_010511.1\|WP_043701341.1\|3980825_3981479_+\|Spy/CpxP-family-protein-refolding-chaperone	gnl\|CDD\|197366	cd09916, CpxP_like, CpxP component of the bacterial Cpx-two-component system and related proteins. This family summarizes bacterial proteins related to CpxP, a periplasmic protein that forms part of a two-component system which acts as a global modulator of cell-envelope stress in gram-negative bacteria. CpxP aids in combating extracytoplasmic protein-mediated toxicity, and may also be involved in the response to alkaline pH. Functioning as a dimer, it inhibits activation of the kinase CpxA, but also plays a vital role in the quality control system of P pili. It has been suggested that CpxP directly interacts with CpxA via its concave polar surface. Another member of this family, Spy, is also a periplasmic protein that may be involved in the response to stress. The homology between CpxP and Spy suggests similar functions. A characteristic 5-residue sequence motif LTXXQ is found repeated twice in many members of this family.	4.38635e-15
NC_010511.1\|WP_012333340.1\|3977045_3977999_+\|glyoxylate/hydroxypyruvate-reductase-A	gnl\|CDD\|240641	cd12164, GDH_like_2, Putative glycerate dehydrogenase and related proteins of the D-specific 2-hydroxy dehydrogenase family. This group contains a variety of proteins variously identified as glycerate dehydrogenase (GDH, also known as hydroxypyruvate reductase) and other enzymes of the 2-hydroxyacid dehydrogenase family. GDH catalyzes the reversible reaction of (R)-glycerate + NAD+ to hydroxypyruvate + NADH + H+. 2-hydroxyacid dehydrogenases catalyze the conversion of a wide variety of D-2-hydroxy acids to their corresponding keto acids. The general mechanism is (R)-lactate + acceptor to pyruvate + reduced acceptor. Formate/glycerate and related dehydrogenases of the D-specific 2-hydroxyacid dehydrogenase superfamily include groups such as formate dehydrogenase, glycerate dehydrogenase, L-alanine dehydrogenase, and S-adenosylhomocysteine hydrolase. Despite often low sequence identity, these proteins typically have a characteristic arrangement of 2 similar subdomains of the alpha/beta Rossmann-fold NAD+ binding form. The NAD+ binding domain is inserted within the linear sequence of the mostly N-terminal catalytic domain, which has a similar domain structure to the internal NAD binding domain. Structurally, these domains are connected by extended alpha helices and create a cleft in which NAD is bound, primarily to the C-terminal portion of the 2nd (internal) domain. Some related proteins have similar structural subdomain but with a tandem arrangement of the catalytic and NAD-binding subdomains in the linear sequence. While many members of this family are dimeric, alanine DH is hexameric and phosphoglycerate DH is tetrameric.	2.13565e-140
NC_010511.1\|WP_150108850.1\|3960236_3961538_+\|MFS-transporter	gnl\|CDD\|340927	cd17369, MFS_ShiA_like, Shikimate transporter and similar proteins of the Major Facilitator Superfamily. This subfamily is composed of Escherichia coli shikimate transporter (ShiA), inner membrane metabolite transport protein YhjE, and other putative metabolite transporters. ShiA is involved in the uptake of shikimate, an aromatic compound involved in siderophore biosynthesis. It has been suggested that YhjE may mediate the uptake of osmoprotectants. The ShiA-like subfamily belongs to the Metazoan Synaptic Vesicle Glycoprotein 2 (SV2) and related small molecule transporter family (SV2-like) of the Major Facilitator Superfamily (MFS) of membrane transport proteins. MFS proteins are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	5.96935e-107
NC_010511.1\|WP_012333328.1\|3955548_3956913_+\|dicarboxylate/amino-acid:cation-symporter	gnl\|CDD\|234968	PRK01663, PRK01663, C4-dicarboxylate transporter DctA; Reviewed.	0
NC_010511.1\|WP_012333332.1\|3962913_3964161_-\|pentapeptide-repeat-containing-protein	gnl\|CDD\|224276	COG1357, COG1357, Pentapeptide repeats containing protein [Function unknown].	2.47871e-32
NC_010511.1\|WP_012333333.1\|3964157_3966101_-\|AI-2E-family-transporter	gnl\|CDD\|223701	COG0628, yhhT, Predicted permease, member of the PurR regulon [General function prediction only].	3.42015e-52
NC_010511.1\|WP_012333334.1\|3966097_3966475_-\|response-regulator	gnl\|CDD\|381100	cd17548, REC_DivK-like, phosphoacceptor receiver (REC) domain of DivK and similar proteins. Caulobacter crescentus DivK is an essential response regulator that is involved in the complex phosphorelay pathways controlling both cell division and motility. It localizes cell cycle regulators to specific poles of the cell during division. DivK contains a stand-alone REC domain. REC domains function as phosphorylation-mediated switches within response regulators, but some also transfer phosphoryl groups in multistep phosphorelays.	2.76212e-43
NC_010511.1\|WP_012333330.1\|3959540_3960167_+\|RraA-family-protein	gnl\|CDD\|180465	PRK06201, PRK06201, hypothetical protein; Validated.	2.35634e-90
NC_010511.1\|WP_012333336.1\|3969065_3970229_-\|hypothetical-protein	gnl\|CDD\|270238	cd13520, PBP2_TAXI_TRAP, Substrate binding domain of TAXI proteins of the tripartite ATP-independent periplasmic transporters; the type 2 periplasmic binding protein fold. This group includes Thermus thermophilus GluBP (TtGluBP) of TAXI-TRAP family and closely related proteins. TRAP transporters are ubiquitous in prokaryotes, but absent from eukaryotes. They are comprised of an SBP (substrate-binding protein) of the DctP or TAXI families and two unequally sized integral membrane components. Although TtGluBP is predicted to be an L-glutamate and/or an L-glutamine-binding protein, the substrate spectrum of TAXI proteins remains to be defined. A sequence-homology search also shows that TtGluBP shares low sequence homology with putative immunogenic proteins of uncharacterized function. The substrate-binding domain of TAXI proteins belongs to the type 2 periplasmic-binding fold protein (PBP2) superfamily, whose members are involved in chemotaxis and uptake of nutrients and other small molecules from the extracellular space as a primary receptor. PBP2 typically comprises of two globular subdomains connected by a flexible hinge and bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap. After binding their specific ligand with high affinity, they can interact with a cognate membrane transport complex comprised of two integral membrane domains and tworeceptor cytoplasmically located ATPase domains. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis.	1.86333e-22
NC_010511.1\|WP_012333344.1\|3981495_3982188_+\|response-regulator-transcription-factor	gnl\|CDD\|223816	COG0745, OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription].	4.12733e-81
NC_010511.1\|WP_012333338.1\|3972124_3975079_-\|response-regulator	gnl\|CDD\|236848	PRK11107, PRK11107, hybrid sensory histidine kinase BarA; Provisional.	5.23715e-67
NC_010511.1\|WP_012333327.1\|3953753_3954551_+\|SDR-family-oxidoreductase	gnl\|CDD\|212491	cd05233, SDR_c, classical (c) SDRs. SDRs are a functionally diverse family of oxidoreductases that have a single domain with a structurally conserved Rossmann fold (alpha/beta folding pattern with a central beta-sheet), an NAD(P)(H)-binding region, and a structurally diverse C-terminal region. Classical SDRs are typically about 250 residues long, while extended SDRs are approximately 350 residues. Sequence identity between different SDR enzymes are typically in the 15-30% range, but the enzymes share the Rossmann fold NAD-binding motif and characteristic NAD-binding and catalytic sequence patterns. These enzymes catalyze a wide range of activities including the metabolism of steroids, cofactors, carbohydrates, lipids, aromatic compounds, and amino acids, and act in redox sensing. Classical SDRs have an TGXXX[AG]XG cofactor binding motif and a YXXXK active site motif, with the Tyr residue of the active site motif serving as a critical catalytic residue (Tyr-151, human prostaglandin dehydrogenase (PGDH) numbering). In addition to the Tyr and Lys, there is often an upstream Ser (Ser-138, PGDH numbering) and/or an Asn (Asn-107, PGDH numbering) contributing to the active site; while substrate binding is in the C-terminal region, which determines specificity. The standard reaction mechanism is a 4-pro-S hydride transfer and proton relay involving the conserved Tyr and Lys, a water molecule stabilized by Asn, and nicotinamide. Extended SDRs have additional elements in the C-terminal region, and typically have a TGXXGXXG cofactor binding motif. Complex (multidomain) SDRs such as ketoreductase domains of fatty acid synthase have a GGXGXXG NAD(P)-binding motif and an altered active site motif (YXXXN). Fungal type ketoacyl reductases have a TGXXXGX(1-2)G NAD(P)-binding motif. Some atypical SDRs have lost catalytic activity and/or have an unusual NAD(P)-binding motif and missing or unusual active site residues. Reactions catalyzed within the SDR family include isomerization, decarboxylation, epimerization, C=N bond reduction, dehydratase activity, dehalogenation, Enoyl-CoA reduction, and carbonyl-alcohol oxidoreduction.	5.05353e-62
NC_010511.1\|WP_012333346.1\|3983462_3984272_-\|SDR-family-oxidoreductase	gnl\|CDD\|223377	COG0300, DltE, Short-chain dehydrogenases of various substrate specificities [General function prediction only].	2.16445e-87
NC_010511.1\|WP_012333342.1\|3979424_3980486_+\|plasmid-partitioning-protein-RepB	gnl\|CDD\|274586	TIGR03454, partition_RepB, plasmid partitioning protein RepB. Members of this family are the RepB protein involved in replicon partitioning. RepB is found, in general, as part of a repABC operon in plasmids and small chromosomes, separate from the main chromosome, in various bacteria. This model describes a rather narrow clade of proteins; it should be noted that additional homologs scoring below the trusted cutoff have very similar functions, although they may be named differently. [Mobile and extrachromosomal element functions, Plasmid functions].	1.17467e-101
NC_010511.1\|WP_012333345.1\|3982184_3983429_+\|HAMP-domain-containing-protein	gnl\|CDD\|236724	PRK10604, PRK10604, sensor protein RstB; Provisional.	5.31558e-46
NC_010511.1\|WP_012333335.1\|3966551_3968819_-\|glycogen-debranching-protein-GlgX	gnl\|CDD\|131155	TIGR02100, Glycogen_operon_protein_GlgX_homolog, glycogen debranching enzyme GlgX. This family consists of the GlgX protein from the E. coli glycogen operon and probable equivalogs from other prokaryotic species. GlgX is not required for glycogen biosynthesis, but instead acts as a debranching enzyme for glycogen catabolism. This model distinguishes GlgX from pullanases and other related proteins that also operate on alpha-1,6-glycosidic linkages. In the wide band between the trusted and noise cutoffs are functionally similar enzymes, mostly from plants, that act similarly but usually are termed isoamylase. [Energy metabolism, Biosynthesis and degradation of polysaccharides].	0
NC_010511.1\|WP_012333341.1\|3978210_3979428_+\|plasmid-partitioning-protein-RepA	gnl\|CDD\|274585	TIGR03453, partition_RepA, plasmid partitioning protein RepA. Members of this family are the RepA (or ParA) protein involved in replicon partitioning. All known examples occur in bacterial species with two or more replicons, on a plasmid or the smaller chromosome. Note that an apparent exception may be seen as a pseudomolecule from assembly of an incompletely sequenced genome. Members of this family belong to a larger family that also includes the enzyme cobyrinic acid a,c-diamide synthase, but assignment of that name to members of this family would be in error. [Mobile and extrachromosomal element functions, Plasmid functions].	0
NC_010511.1\|WP_012333329.1\|3956986_3959272_+\|NADP-dependent-malic-enzyme	gnl\|CDD\|183799	PRK12862, PRK12862, malic enzyme; Reviewed.	0

>NC_010511.1|WP_012333336.1|3969065_3970229_-|hypothetical-protein
MTRLAALAISVALLAGAPGSPAQAREAAPAAESEGMVGDSMNAATVSIVTGTPGGTYFRIGADLAFVLDDGKQLRILPILGKGAGQNAYDLLFLKGVDLAFLRTDTLEQLREDKRLTKVDTRIQYISKLFDDELHIIGPVDVTDARQLAGKRVTFDVKGSGTDYSGRAMFRKLGIAVQAINVDQPTALEMLRKGEVDAVVSVAAKPVAMIAGFDPGGKFHLIPAKYAAAVEDAYLPASLTKQDYPKLMGQADEVQTLAVGTVLGVYKPVKGSARYAKLTRFVDAFFGKFDEFLAPQRHPKWREVNLAAEVSGWTRFLPAQKWLDAHREPQTSGGGDFTAFLNDQQPSAATGKEELYQAYLQWRKGRGRAINSLGERVPDRQTKGSSF
>NC_010511.1|WP_012333335.1|3966551_3968819_-|glycogen-debranching-protein-GlgX
MSRVDGGRVSAPYVMARPRIREGSPNLRGTTWDGLGVNFALFSAHATRVELCLFDDSGKTEIERIDLPEYTNEIWHGYLPDARPGTIYGYRVHGPYEPDEGHRFNPHKLLLDPYAKALVGSITWDPALFGYRLESGDDLTFDDRDSAPFTRKGRVIDPAFTWGRDRKPDVPWERTIIYEAHVKGLTKLHPGVPERLRGTYAGLGQPAVLDYIRSLGVTAVELLPVHSFVQDDYLRQKDLWNYWGYNTISFFAPARRYAAVPDFAFSEFKEMVARLHGAGLEVILDVVYNHTAEGNERGPTLSFKGIDNASYYRLLPDQRRYYINDTGTGNTVNLSHPRVLQMVTDSLRYWATEMRVDGFRFDLATILGRESYGFDEGGGFLDTCLQDPVLNSVKLIAEPWDCGPGGYQVGGFPPGWAEWNDRFRDDVRAYWRGDEGLLPALAARFTASADKFDKRGRKPWASVNFLTAHDGFTLADTVSYAEKHNEANGEENRDGHSHNLSSNYGVEGPTADPEIRAVRFRQMRNMLATLFLARGTPMLLAGDEFARTQRGNNNAYCQDNEISWLDWQAIGPAERDLAEFTQRLILLRNALPILMRGRFLTGRYDEELGVRDVAWLTPDGDEMSPEHWGDGKARSLAVLLDGRAQETGIKQQGSEATLLLLINAYHDVVRFTLPKTAGGHEWVRLIDTNLPEGQETRSFQAGGAYEVTGRSMLVMVLRPDAGEASVAVERSFTHVMQAFARATAEHVAFGPAFRG
>NC_010511.1|WP_012333334.1|3966097_3966475_-|response-regulator
MTKILLVEDHEEIWDFLSRRLTRRGYEVVMAHDGDAGVQQARSLRPDVILLDMNLPVLDGWSVARALKSSPDTQSIPIIALTAHAMSGDREKAIQAGCDDYHPKPIDFAKLLGQIGAVTGAGAPP
>NC_010511.1|WP_012333333.1|3964157_3966101_-|AI-2E-family-transporter
MSEDPVTARWLRQALPAFVVLAGLLGVLALAVLLVMGREILVPITLAIFLSFVLVPAVRALRRLRIPRVPAVLLVVLLAFGALGTVGSLLAGEAAQLAADLPRYSLTMRDKIKLLQGATAGGGGVSRLLDMVADLSRELQPPPEPKDRAAPAAGTPLKVEVVEARPSVLAALGTYAAPVLHPLATTGLILLFSVVILLQREDLRNRAIRLAGSGDLRRTTAAIDDATARLTRFFLAQLGLNTAFGVVIGLGLWIIGIPSPVLFGVIAGILRFVPYIGAVIGALLPLVLAAAVDPGWTMVLATAALFLVVEPVAGHVVEPLLYGHSTGLSPVAVILAATVWAFLWGPVGLVLATPLTVCLVVLGRHVERLEFLEVLLGDGPALAPEEIFYQRMLAGDPGEAIDQGVQFLKARPLVTYYDEVVLAALRMAQDDFARGTVARARQDEVGEAFRTVVERLGATRPSLWRRALGREAAAAVAAVGPDPRAAATVLDRAALPPRWRGPAPVLCVSSGGAFDLATTRMLSQILDRHGLPSRVTTLRDLLREGAEAVDPRATALVCYSYLEPISLSQIRYVVRQTRRTLPGVTVLVGFWGERDPGTLARLRRATSADVLVTSLGDALGAVLARAAPAPQPQRGGAPSPAAAPVRA
>NC_010511.1|WP_012333332.1|3962913_3964161_-|pentapeptide-repeat-containing-protein
MSAPAGPGARPAAAREAPPRAEGPLDLAGAELPPGTDLVEADLSGANLARARLSGILARSARFDGARIEEADFSGADLSGAHFATVAGGQARFSGAMMEDARFCGATLRFATLAGGLLDGADFTGADLWGADFTDADADDTLFRRARLDEAKLVNVNLTGAVFEGASLAKASLAGSRLSRANFVEAKLDGADLSGADLSDARLVRLDLTSCRLRHARFAHAWLEGTRLRVDQLGGAVGEEVAGDYAAAVASYLVVERNQRSIGDREGASWAFKRARRMGRHHAGALTRAAWREGAWRAGLRHGSDWLSDRFVEWLCDYGESLTRIVRAFALAILVFAALYGVTGGLIPEGRDGVPTYNPLDLVSYSALNMMTANQPELGIKPVGRVTNILVGSQGALGIILMGLFGFVLGNRLQR
>NC_010511.1|WP_150108850.1|3960236_3961538_+|MFS-transporter
MSVAMHAGGIKEKAKQATGAAVFGTFIEYYDFSVYGYVAATLSLVFFPAGDAVANLLNTLAVFGLAFLVRPIGAWYFGQLGDRRGRRTSLIATITLMGVASALTGLLPSYQTIGIVAPVLLVLMRLLQGFSTGGEIGGAASYIREWAAPDRRALYISFLPSVAQLGKGLAAALGGLMAAMLTRESMIEWGWRIPFLLAGPLAVLTIWMRLSIEDSPEFAALSASHKTTKAPLASLFQQYPTALAKVMLISAVQNIGTYIGTVFVSVYFSEVLGFSKAEAATVVLLAVILASFLIPLAGMIGNRVGGKTLLLIAYTAYLLLTLPEFMLMNQNNIVLALLGLSIGIIPYALCQAGTYATMPEMFPTQIRHTGVAFGHSVGAVVGGGGGPYFAAWLISVTGNTYMPAYILMGAGLVGLVVVGLTVRRNVGGTHLYA
>NC_010511.1|WP_012333330.1|3959540_3960167_+|RraA-family-protein
MKTIEQAKSLELAELFREAPVAVISDNLDRLPGFLDMRPYHRGAKLVGPARTVRTRPGDNLMIHKVLELVQPGEVIVVAGEGDTTRALIGEIIVRIAQMRGVAGFVVDGAIRDLGTISAGTFPCFARGVIHRGPYKDGPGEIDVPIAMSGGTVVSPGDIIVGDEDGVVSFPQSIARDLSGKVEAHLAKEAAILKSIANSTYTGAYSKS
>NC_010511.1|WP_012333329.1|3956986_3959272_+|NADP-dependent-malic-enzyme
MADNVSEELEHAALAYHCYPYPGKLAVVPTKPLGTQRDLALAYSPGVAIPCEEIAADPDKAADYTSRQNLVAVVSNGTAVLGLGAIGALASKPVMEGKAVLFKKFAGIDVFDIEVDERDVDRMVDVVCSLEPTFGGINLEDIKAPECFEIEEKCKTRMKIPVFHDDQHGTAIIVSAAVLNSLELSGKKIESIKVVTSGAGAAALATLNLLVSLGVPREHIWVTDIEGVVYAGRNELMDRWKEVYAQTTDKRTLAEVIDGADVVIGLSAAGVIKPEMLKVMKPNPLIMALANPTPEIMPELAREARPDALICTGRSDFPNQVNNVLCFPYIFRGALDVGASTINEEMKSAAVRAIAALAREAPSDVVARAYGGEARPFGAESLIPSPFDPRLILRIAPAVAKAAMDTGVARRPVADIEAYTESLGRFVFRSGFVMKPIFTAARASPRRVAYAEGEDERVLRAVHAVVEERIARPILIGRPAVIEMRLKRFGLSIKAGRDFDFINPEDDPRYRDYVATLVERAGRKGITPDAARTLVRTNATIIGSLALMRGDADALLCGLEGRFRSNLDHITNIVGYGPGMHQLAALSLMITSQGPLFLAHTHVRPNPTAEEIAEMTCACAGHVRRFGITPKVALLSYSDFGSGDTESAVKMRKALALVQELAPDLEADGEMAADTALSQLIRDRVNPGSKLKGEANLLILPNLDAANIAFQLVRVLADALPVGPILIGPSKPVHILTPSVTARGVTNMTAVAVIEAQSQVN
>NC_010511.1|WP_012333328.1|3955548_3956913_+|dicarboxylate/amino-acid:cation-symporter
MTAAISETDHQTVKWYSHLYVQVLGAITVGVVLGHFYPQIGEQMKPLGDAFIKAIKMIIAPIIFFAVVHGIASMGDMKKVGRVGLKALIYFEVVTTLALIIGLVVVNLWKPGVGINLDLSTVDAKSIASFTAEAKDQSTVHFLMEIIPSTVVGAFAKGEILQVLFFAILFAFGLQALGERGGGVLRLIDTVGHVFFKIVGYIMKAAPIGAFGAMAFTIGKYGISTLLSLGNFMLSFYTTCLLFIFVVLGSIAALHGFSILKFIRYIKEELLIVLGTSSSESVLPRMIAKMENLGADKSVVGLVVPTGYSFNLDGTCIYLTMAVIFLAQATNIDLTVWQELGIIGVLLLTSKGAAGVTGSGFIVLAATLASVGTIPVASIALILGVDRFMSEARALTNVIGNGLATIVVAKWEGVLDEEVLRRRLNAETDAEADEPEDVAIADDAKSGPPQPITA
>NC_010511.1|WP_012333327.1|3953753_3954551_+|SDR-family-oxidoreductase
MSTSTPCSSAGAERGARAAERGAGRTLLLTGASRGIGHATVKIFAEAGWRVITCARRPFDPNCPWESGRIDHVPVDLADPAATGRAVARVKELIGDGPLHALVNNAGISPKTPAGGRLSSVDTPLQTWMDVFHVNFLAPVILARGLLDNLVAAGGSIVNLTSIAGTRVHPFAGAAYATSKAALSCLTREMAFDFAPYGVRVNAIAPGEIRTEILSAETEAHLAPTIPMRRIGTPAEVASVIYFLCSQHASYVTGEEVQINGGQHV
>NC_010511.1|WP_043701338.1|3970444_3971437_-|hypothetical-protein
MVAAAGLSACLAAASAPAQETSDPSGQGAAPPRAKEVQGDAPLSTVKVPYGERVALPVANPPPRRADYASVYMTGLPQGSTVSDSVHDVVVGDDVQAIDISSFNLEGLFVLLPRDLASRSHEVFVASVLAFPPWSGEGNPVQTETLSTMVIIPEVSSLPPLALDVPQPAVAVMSVPPAAAPPRGPGRDVASRRDVASRNVPSRDVPSTDQPAADRAGPRATGAAIAEPPSPAQSPPAADPGAGDEPSAVALLARAGQLLQVGNVSGARLLLLRAGSADAMELLAQTYEEAFLRRLGVRGLRGDPERARSYSEAAARLRQGGVQRQARSAP
>NC_010511.1|WP_012333338.1|3972124_3975079_-|response-regulator
MTEETPSPSRRLPRFARPRSRAALLAVLLLGVSFAAALLNYLSGTRAAAEAVRLNGVIAQSERVLSTLKDLETGLRGYILTGDGAYLDPYAAALTHIDPELDRLDGFDRDPDTRARRRRLIADQRAYAARAVAARREQGPEAASALVRSGEGKRIMDALRTLTAAVQDRAVADLDRIAARERLRSPLLQVLVLASALAAAGLLARLAILRRREGRRTAALLAGVLENAPVGLGFLDRDLTIRHMNRALESMSERGLGTGVGEPIWALLPSLRDALAPKLAAARDEGLVTANVEVGVPTPSAPGSVRYFQMSFFPLRRDVDDRAARAEGVGLVMSDVTLRKLSEARTRESEERFRSLTEATSAIVWRTTPEGTFAQVTSEWTRFTGQTPEEAAGLGFLDAVHPEDRAATRAAWEQAVATHALYAIEHRLRRHDGIYRHMEVRAVPILEKDGRVREWVGAHADTTARKEAELALEAAREAAEEANAAKSQFLANMSHELRTPLSAVIGYAEMLQEEMEDLGASALLPDMRKIEANARHLLGLINDVLDISKIEAERMEVYAEDFDVAATLQDVGATVGSLIAKKDNALVLDLAEGLGRAHTDVTKLRQCLINLLSNAAKFTEGGRIVLSAERLRRDGRDRLRFRVADTGIGMSAEQQARLFERFTQADASTTRRFGGTGLGLAITRAFVEMLGGAIAVESRAGEGTTFTIELPVRYRAEAEAGEDEADAAAPAPAAEAAREAGGDLVLVIDDDPATRDLLARFLRRDGFRVAAAPDGRAGLDQARALRPRVILLDVTMPRMDGWEVLRALRADPDLAATPVIMVTVLDEQNLAFSLGATDYLHKPVAWKQLKEAMERFRPAIHEGPVLVVDDDPDVRERITALLTREGWRAASAANGRAGLDAVAVRKPGLILLDLMMPELDGFGFLRGLRARPEWRDIPVVVLTAKDVTADERRRLAGQADRVLQKGGLSMADLAATVRSLLVPS
>NC_010511.1|WP_012333339.1|3975285_3976935_+|DAK2-domain-containing-protein
MTHFLTRRETLVADALDGLLLAPAEPGLARLDGDPEIRVVLRAERDRTKVAVISGGGAGHEPAHAGFVGEGLLDAAVCGDIFASPSVDAVLAAILAVAGPAGCLLVVKNYVGDRINFGLAAEKARALGHAVEVVIVGDDVALPDSARPRGIAGTVLVHKAAGHAAAAGQPLAAVRAAAEATARAVRTLGVATATCAIPGQGAEARIPAGEAELGLGIHGEPGVQRIALPPLPALVADMVGRFGPEIREAPQLALLVNNLGGVSAVEMAAVAREVLRGPLGPRIAWLLGPAPVVTALDMRGFSLSLMPVDAAAAAMLTAPVRAPAWPAPRRVRGEAAALPLPAALRPAPDEPSADPASRRLLEAACRALIAAQAALDALDARVGDGDTGTTFASGARRVLAEIDALPLAEPAALCRALAERLSRAMGGSSGVLLSILLAEAGHRLREGADPGEALAAGVARMQFYGGAREGDRTMLDALLPAARALAEGGGLAAAARAARAGAQATAAMAAARSGRSSYLGVRDLAGTADPGAEAVARAFEALAEAAGSP
>NC_010511.1|WP_012333340.1|3977045_3977999_+|glyoxylate/hydroxypyruvate-reductase-A
MHEPIAFVGSLDAREEAAFLAALRAALPEESLVPFRALTPAQREAVRVAVVANPDPAEVARLPRLAWIQSLWAGVERLVRDLGAAGVPIVRLVDPELARTMAEAVLAWTFFLQRDMPAYRRQQEAGIWRPLPYRAPAEMTVGLLGFGLLGAAAAGRLDEAGFRVAAWSRTPRARPGAEAGATLAGPDGLARLLAGSDVVVCLLPMTPATRGLLGAAQFAAMKPGAALMNFGRGPIVATDALLAALESGQLSHAVLDVFDTEPLPPESPLWRHPGVTVLPHVTAPTNPRSAAAIVAENLRGYRRTGRIPAAVDAARGY
>NC_010511.1|WP_012333341.1|3978210_3979428_+|plasmid-partitioning-protein-RepA
MNQAATAIPAPPLPISPSAMIGAHAAVLRAQLQAISSGLFPPLSAKTLRRFTSAEVARIIGITVSRLQQLAAEGLGPQPEVSPTGRRSYSLADIHGLRAYLDEQARAGRRYQPRRGEGDPLQVVAVANFKGGSGKTTTSAHLAQHLVLKGYRVLALDLDPQASLSALLGVQPELEVGESETLFGAIRYDAARRPLEAIIRPTYFTGLDLVPANLELMEFEHETPRALGLRRPGEPLFFDRVAQAIESVEERYDVVVIDCPPQLGYLTLSALCAASALLITVHPQMLDVASMSQFLAMTEDLLGVVAEHGGRLQYDWLRYLVTRYEQQDAPQTRIVGMLRTLFEDAVLTAPMLKSSAISDAGLSKQTLYEIGREGVTRSTYDRALESLEAVNGEIEGLIRRAWGRA
>NC_010511.1|WP_012333342.1|3979424_3980486_+|plasmid-partitioning-protein-RepB
MSRKSNLDALFAAKPVHKPVHLPAPLPAPSPEPDGFAAANQTPDGTEFAAANPPAAPRRRSGAIGAMSQTLRGLAAQADAAASLEAGSAVVEIEPGLIDASFIADRVADPTDPSLASLVESVRESGQQVPVLVRPHPVSAGRYQIAYGRRRVRAAQILARPVRAVIRPLTDAELVIAQGKENLERRDLSYIERAFFARRLEEHGFPRDTITAAMGVGKGDLSTLISVARTVPDDILAAIGPAPAAGRPRWMLLAEGIRTADRAALSALLADPAFRAKPTDQRFAAILAAVAAPPARGGRPQVWTDPQGRRLARVERGADRVALSFDERLEPGLADYILDQLPEILAAYRRSRS
>NC_010511.1|WP_043701341.1|3980825_3981479_+|Spy/CpxP-family-protein-refolding-chaperone
MSNGAMNGPAAQAPAPRRILRRTALALGLLLAGGTAGLAVAMGGAPDGFGFRDPGQRLARLQFMARRALDSVGATSDQENRIHDIIASASAALMKEGPTHEEMRRRLADLLKAPTVDRAAIEALRAEMVRSVDARSKIIAGALVDAAGQVSAEQRAKLVDRVASAMEQHRGFGRWRHPWGGEGGRPERGPGWPQFGGAGPQPGGAGPQPGGAGPERN
>NC_010511.1|WP_012333344.1|3981495_3982188_+|response-regulator-transcription-factor
MAERLLLIDDDRRLAAMVAEYLSAEGYAVACQPTAREGHDALRRERFDAVILDVMLPDGDGFELCRQIRTHSRVPILMLTAKGEDTDRIIGLEIGADDYLPKPFNPRELLARIRALLRRQRAPQEARLDFGRLQIDPGSRVVRLDGVERRLTSHQFDLLLAFATHAGRVLSRERLMDLVKGEDLDAFDRSIDVHVSRLRALIEDDPRHPRRLLTIRGAGYVFAREQDAER
>NC_010511.1|WP_012333345.1|3982184_3983429_+|HAMP-domain-containing-protein
MRSVRRRLFWKIYLTLLASLVGAAIAMAGLWWMLGESPHKRWEALETHIAHEAVALAGPPAEAEPAVRRLSGLFGADAALYDRGGALLAARGTRAVLLGGEATGPPVRWVLRSALPDGRTLLVSIHPSPSTRIARIATLTLLVAAFVALAAFPVTARLTRRLERLRAGVARWGEGDLRARVDEGGGDEVAAVARTFNLAAGRVDALLAAQRRLLANASHELRSPLARLRMAVDLWAGRPEAARAEIVRNLGELDTLVDEILLSSRLDHAEAGLDRRETVDLLGLAAEEAARVGAEVEGVPVSVRGDPVLLRRLLRNLLENGAAHGAPPVRVRAEPSGARARLVVSDHGPGIPAAERERVFEPFYRPRGRREEAGGWGLGLSLVRQIAQRHGGLALCEGAEAGGSRFVVDLPRAP
>NC_010511.1|WP_012333346.1|3983462_3984272_-|SDR-family-oxidoreductase
MTLSSLGTALVTGASSGIGAIYADRLAARGHDLVLVARNRAKLADLAAGLADRTGRSVEVVAADLGDRTDLRAVERLAASDASLTMLVNNAGIGATAPLLASDVDAMERLIDLDVTALMRLTYAAAPAFAARGRGTIVNIASSVAIGPEVLNGVYGGAKAFVLAFSQSLHHELAGKGLRVQAVLPGATATAFWGLAGVPVEHLPGEIVMRAADLVDAALAGLDAGEVVTIPSLPDAAQWQAYEAARQALLPNLSRAEPAARYRVGAARA

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Crispr_ID: NC_010511_24

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_010511_24

4167983-4168117

Orphan

Consensus_repeat	Method
GCCGACATCCGCATGGCCGAAATCGGAGATGGCGAAGCCATCAACCGGATG	CRISPRCasFinder

1 spacers

The CRISPR arrays of NC_010511_24

>merge|NC_010511|24|4167983-4168117|CRISPRCasFinder
GCCGACATCCGCATGGCCGAAATCGGAGATGGCGAAGCCATCAACCGGATGACGTATGACAAGCCCGCGCGGCGCCTGAGCGAAGCCGACATCCGCATGGCCGACATCGGAGATGGCGAAGCCATCAACCGGATG

>NC_010511|24|24|4167983-4168117|CRISPRCasFinder
GCCGACATCCGCATGGCCGAAATCGGAGATGGCGAAGCCATCAACCGGATG	ACGTATGACAAGCCCGCGCGGCGCCTGAGCGAA
GCCGACATCCGCATGGCCGACATCGGAGATGGCGAAGCCATCAACCGGATG

Protein	Signature genes	Signature genes Name	Protein_function
NC_010511.1\|WP_012333516.1\|4168319_4169603_+\|ArgE/DapE-family-deacylase	unknown	unknown	gnl\|CDD\|180721
NC_010511.1\|WP_012333513.1\|4165209_4166736_+\|phytoene-desaturase	unknown	unknown	gnl\|CDD\|274273
NC_010511.1\|WP_012333511.1\|4162478_4164224_+\|magnesium-chelatase-subunit-D	unknown	unknown	gnl\|CDD\|237378
NC_010511.1\|WP_012333514.1\|4166716_4167772_+\|phytoene/squalene-synthase-family-protein	unknown	unknown	gnl\|CDD\|173831
NC_010511.1\|WP_012333524.1\|4179039_4179834_+\|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|224041
NC_010511.1\|WP_012333519.1\|4173814_4174468_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|235904
NC_010511.1\|WP_012333517.1\|4169795_4171883_-\|transketolase	unknown	unknown	gnl\|CDD\|223100
NC_010511.1\|WP_012333522.1\|4176864_4178160_+\|ABC-transporter-substrate-binding-protein	unknown	unknown	gnl\|CDD\|372585
NC_010511.1\|WP_012333509.1\|4160066_4161278_+\|5-aminolevulinate-synthase	unknown	unknown	gnl\|CDD\|236370
NC_010511.1\|WP_050777495.1\|4174742_4175363_+\|ANTAR-domain-containing-protein	unknown	unknown	gnl\|CDD\|226230
NC_010511.1\|WP_012333512.1\|4164235_4165117_+\|alpha/beta-fold-hydrolase	unknown	unknown	gnl\|CDD\|132100
NC_010511.1\|WP_012333507.1\|4158146_4159208_+\|magnesium-protoporphyrin-IX-monomethyl-ester-(oxidative)-cyclase	unknown	unknown	gnl\|CDD\|237458
NC_010511.1\|WP_012333525.1\|4179844_4181062_+\|NAD(P)/FAD-dependent-oxidoreductase	unknown	unknown	gnl\|CDD\|224171
NC_010511.1\|WP_012333518.1\|4171900_4173742_-\|glycoside-hydrolase-family-15-protein	unknown	unknown	gnl\|CDD\|225922
NC_010511.1\|WP_036270252.1\|4157847_4158150_+\|hypothetical-protein	unknown	unknown	unknown
NC_010511.1\|WP_012333508.1\|4159212_4160019_+\|DUF3623-domain-containing-protein	unknown	unknown	gnl\|CDD\|372016
NC_010511.1\|WP_012333515.1\|4167777_4167921_+\|hypothetical-protein	unknown	unknown	unknown
NC_010511.1\|WP_012333521.1\|4175359_4176364_+\|ABC-transporter-substrate-binding-protein	unknown	unknown	gnl\|CDD\|372585
NC_010511.1\|WP_012333523.1\|4178159_4179026_+\|nitrate-ABC-transporter-permease	unknown	unknown	gnl\|CDD\|130251
NC_010511.1\|WP_012333510.1\|4161375_4162482_+\|magnesium-chelatase-ATPase-subunit-I	unknown	unknown	gnl\|CDD\|184036

Protein	Function_ID	Function_description	E-value
NC_010511.1\|WP_012333516.1\|4168319_4169603_+\|ArgE/DapE-family-deacylase	gnl\|CDD\|180721	PRK06837, PRK06837, ArgE/DapE family deacylase.	0
NC_010511.1\|WP_012333513.1\|4165209_4166736_+\|phytoene-desaturase	gnl\|CDD\|274273	TIGR02734, Phytoene_desaturase_lycopene-forming, phytoene desaturase. Phytoene is converted to lycopene by desaturation at four (two symmetrical pairs of) sites. This is achieved by two enzymes (crtP and crtQ) in cyanobacteria (Gloeobacter being an exception) and plants, but by a single enzyme in most other bacteria and in fungi. This single enzyme is called the bacterial-type phytoene desaturase, or CrtI. Most members of this family, part of the larger pfam01593, which also contains amino oxidases, are CrtI itself; it is likely that all members act on either phytoene or on related compounds such as dehydrosqualene, for carotenoid biosynthesis. [Biosynthesis of cofactors, prosthetic groups, and carriers, Other].	0
NC_010511.1\|WP_012333511.1\|4162478_4164224_+\|magnesium-chelatase-subunit-D	gnl\|CDD\|237378	PRK13406, bchD, magnesium chelatase subunit D; Provisional.	0
NC_010511.1\|WP_012333514.1\|4166716_4167772_+\|phytoene/squalene-synthase-family-protein	gnl\|CDD\|173831	cd00683, Trans_IPPS_HH, Trans-Isoprenyl Diphosphate Synthases, head-to-head. These trans-Isoprenyl Diphosphate Synthases (Trans_IPPS) catalyze a head-to-head (HH) (1'-1) condensation reaction. This CD includes squalene and phytoene synthases which catalyze the 1'-1 condensation of two 15-carbon (farnesyl) and 20-carbon (geranylgeranyl) isoprenyl diphosphates, respectively. The catalytic site consists of a large central cavity formed by mostly antiparallel alpha helices with two aspartate-rich regions (DXXXD) located on opposite walls. These residues mediate binding of prenyl phosphates. A two-step reaction has been proposed for squalene synthase (farnesyl-diphosphate farnesyltransferase) in which, two molecules of FPP react to form a stable cyclopropylcarbinyl diphosphate intermediate, and then the intermediate undergoes heterolysis, isomerization, and reduction with NADPH to form squalene, a precursor of cholestrol. The carotenoid biosynthesis enzyme, phytoene synthase (CrtB), catalyzes the condensation reaction of two molecules of geranylgeranyl diphosphate to produce phytoene, a precursor of beta-carotene. These enzymes produce the triterpene and tetraterpene precursors for many diverse sterol and carotenoid end products and are widely distributed among eukareya, bacteria, and archaea.	2.27571e-77
NC_010511.1\|WP_012333524.1\|4179039_4179834_+\|ABC-transporter-ATP-binding-protein	gnl\|CDD\|224041	COG1116, TauB, ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component [Inorganic ion transport and metabolism].	1.69101e-126
NC_010511.1\|WP_012333519.1\|4173814_4174468_-\|hypothetical-protein	gnl\|CDD\|235904	PRK06995, flhF, flagellar biosynthesis protein FlhF.	1.11289e-05
NC_010511.1\|WP_012333517.1\|4169795_4171883_-\|transketolase	gnl\|CDD\|223100	COG0021, TktA, Transketolase [Carbohydrate transport and metabolism].	0
NC_010511.1\|WP_012333522.1\|4176864_4178160_+\|ABC-transporter-substrate-binding-protein	gnl\|CDD\|372585	pfam13379, NMT1_2, NMT1-like family. This family is closely related to the pfam09084 family.	1.71089e-123
NC_010511.1\|WP_012333509.1\|4160066_4161278_+\|5-aminolevulinate-synthase	gnl\|CDD\|236370	PRK09064, PRK09064, 5-aminolevulinate synthase; Validated.	0
NC_010511.1\|WP_050777495.1\|4174742_4175363_+\|ANTAR-domain-containing-protein	gnl\|CDD\|226230	COG3707, AmiR, Response regulator with putative antiterminator output domain [Signal transduction mechanisms].	1.83862e-53
NC_010511.1\|WP_012333512.1\|4164235_4165117_+\|alpha/beta-fold-hydrolase	gnl\|CDD\|132100	TIGR03056, bchO_mg_che_rel, putative magnesium chelatase accessory protein. Members of this family belong to the alpha/beta fold family hydrolases (pfam00561). Members are found in bacterial genomes if and only if they encoded for anoxygenic photosynthetic systems similar to that of Rhodobacter capsulatus and other alpha-Proteobacteria. Members often are encoded in the same operon as subunits of the protoporphyrin IX magnesium chelatase, and were once designated BchO. No literature supports a role as an actual subunit of magnesium chelatase, but an accessory role is possible, as suggested by placement by its probable hydrolase activity. [Energy metabolism, Photosynthesis].	1.48566e-90
NC_010511.1\|WP_012333507.1\|4158146_4159208_+\|magnesium-protoporphyrin-IX-monomethyl-ester-(oxidative)-cyclase	gnl\|CDD\|237458	PRK13654, PRK13654, magnesium-protoporphyrin IX monomethyl ester cyclase; Provisional.	0
NC_010511.1\|WP_012333525.1\|4179844_4181062_+\|NAD(P)/FAD-dependent-oxidoreductase	gnl\|CDD\|224171	COG1251, NirB, NAD(P)H-nitrite reductase [Energy production and conversion].	3.66113e-164
NC_010511.1\|WP_012333508.1\|4159212_4160019_+\|DUF3623-domain-containing-protein	gnl\|CDD\|372016	pfam12291, DUF3623, Protein of unknown function (DUF3623). This family of proteins is found in bacteria. Proteins in this family are typically between 261 and 345 amino acids in length.	5.16827e-113
NC_010511.1\|WP_012333518.1\|4171900_4173742_-\|glycoside-hydrolase-family-15-protein	gnl\|CDD\|225922	COG3387, SGA1, Glucoamylase and related glycosyl hydrolases [Carbohydrate transport and metabolism].	6.45863e-137
NC_010511.1\|WP_012333521.1\|4175359_4176364_+\|ABC-transporter-substrate-binding-protein	gnl\|CDD\|372585	pfam13379, NMT1_2, NMT1-like family. This family is closely related to the pfam09084 family.	1.7107e-62
NC_010511.1\|WP_012333523.1\|4178159_4179026_+\|nitrate-ABC-transporter-permease	gnl\|CDD\|130251	TIGR01183, Nitrate_transport_permease_protein_NrtB, nitrate ABC transporter, permease protein. This model describes the nitrate transport permease in bacteria. This is gene product of ntrB. The nitrate transport permease is the integral membrane component of the nitrate transport system and belongs to the ATP-binding cassette (ABC) superfamily. At least in photosynthetic bacteria nitrate assimilation is aided by other proteins derived from the operon which among others include products of ntrA, ntrB, ntrC, ntrD, narB. Functionally ntrC and ntrD resemble the ATP binding components of the binding protein-dependent transport systems. Mutational studies have shown that ntrB and ntrC are mandatory for nitrate accumulation. Nitrate reductase is encoded by narB. [Transport and binding proteins, Anions].	1.96221e-100
NC_010511.1\|WP_012333510.1\|4161375_4162482_+\|magnesium-chelatase-ATPase-subunit-I	gnl\|CDD\|184036	PRK13407, bchI, magnesium chelatase subunit I; Provisional.	5.80452e-160

>NC_010511.1|WP_012333515.1|4167777_4167921_+|hypothetical-protein
MLVALLDIALPFGIVLGLGLWQLRLLRRDRARGEEVARASRERPPEP
>NC_010511.1|WP_012333514.1|4166716_4167772_+|phytoene/squalene-synthase-family-protein
MPLSSPDRPRAGPADHAACRAAIRGGSRSFYAASWLLPRAVRRDAYGLYAFCRLSDDAVDGPRARADAVERLRLRLAAACAGRPFDDPADRALAEVLDRHGIPPALPAALLDGLAWDAAGRRYRDLSDLVAYASRVAGAVGAMMTLVMGERSPEALARACDLGIAMQFTNIARDVGEDARAGRLYLPEAWLREAGLDPDAFLARPAPSPALAAVLTRLLRAADLLYARSEAGIALLPAPCRPAVRAARLIYAEIGRAVERNGHDSVTSRARVAGARKGRLLARAAATPSRRAACGPALPEAAFLVEAVAAHPFAPPPRDPAWWDLGHKAVRLLDLIEVLRERESLGDAAPS
>NC_010511.1|WP_012333513.1|4165209_4166736_+|phytoene-desaturase
MLTLDVAPPRHTARPRKPHAVVIGSGFGGLAAAVRLGARGYRVTVLERLGQPGGRARVHRQDGFTFDAGPTIVTAPFLFEELWALCGRRLDEDVTLVPMRPFYRIRFHDGASVDVSGDEAAMRAQVARIAPGEVEAYGRFMAASEEICRVGFEQLGHVPFGEAGTMLRVAPDLLRLGGHRSVHGLVSRYFRDERLRTVFSFHPLLIGGSPFRASAIYCLIAALERRWGVHWAMGGTGRLVEGLVRLIEGQGGRLRCHAEVTRIRVEGGAATGVDLADGTRLPADIVVSNADSVVTALDLLPPEARGWRERRLARASSSMGLFVWYFGTRRTYPDVPHHTILLGPRYRDLLADIFRRKVLAEDFSLYLHRPTATDPGLAPPGCDAFYVLSPVPNLDGGQDWAALAEPYRQRIARHLEATLLPGLSEAVVTSRVTTPREFRDDFRAYRGSAFGLEPILSQSAYFRPHNRSDRVRHLYLVGAGTHPGAGLPGVLSSSRILDRVVPDASVFA
>NC_010511.1|WP_012333512.1|4164235_4165117_+|alpha/beta-fold-hydrolase
MTSDRPAFAREGRDWPNREASRFVAAGGLTWHVQEAGTGPCLLLLHGTGAATHSWRGLLPLLARRFRVVAPDLPGHGFSDPLPMPSLPRMARAVAELVRGLGIAPQVAVGHSAGAAILVRLCLDGALAPRLLVGLNAALKPFPGMAGLVFPTMARMLFLNPVVPRVFAWSADRKAVARLIEGTGSTLDREGLDLYRRLFQMPGHVAGALGMMANWDLVGLDRELPRLAVPLLLLAGAQDRTIAPDVSFGVAERLGGRPRVELLRGLGHLMHEERPELVAGSIEEAARREGVEA
>NC_010511.1|WP_012333511.1|4162478_4164224_+|magnesium-chelatase-subunit-D
MSAAAETWARACLAAALFARDPAGLGGVRLRARPGPVREAWLARLRALLPAGRPVTRLPAGIADDALLGGLDLAATLRAGRPVVEPGLLARSHGGVVVVPMAERLDAGIAARLARVLETGAVDLARDGVAARLPAACGLVLLDEGDGEDEAVPSALLERAAFHLDLDGLTLRDVSEPAPPDSAPVSGETAAAPVEARAAERLCALAAQLGIASLRAPIQALRAARQNAGREGRSALAEPDLAAAAALVLAPRATRWPAEAEAEPPPPEAPPEEAEGASDPGGGEAAEDRLLAAVAAALPAGLLARLTDAGAPGAAPGRAGGEARQARSGRPVGARPGDPRRGPLALSETLRAAAPWQRLRRGAEAERLRLAPEDIRVRRFVHRAGTTTIFAVDASGSAALERLAEAKGAVELLLAECYVRRDRVALVAFRGRGAELLLPPTRALVRAKRALAALPGGGGTPLAAGIEAAALLAAAERRGGRIPVVLLLTDGRANIGRGGAPGRAQAAADALAAGRALAAGGTRALVIDTAAQPQDGARRLAEAMAARYLPMPRADAALLSEAVRREAPPRGAAPRGTAPRG
>NC_010511.1|WP_012333510.1|4161375_4162482_+|magnesium-chelatase-ATPase-subunit-I
MALTQSALSRRALKPGPAASPAPAAAAPAPRPPYPFTAIVGQEAMRRALLIGAVDPSVGGVLVFGDRGTGKSTAVRALAALLPPMRAVAGCPYACDPADEAFLCPACRARAPQGLPVQSVPVPVVDLPLGATEDRVVGALDIGKALTRGEKAFEPGLLARANRGFLYIDEVNLLEDHLVDLLLDVAASGVNTVEREGLSLRHPARFVLVGSGNPEEGELRPQLLDRFGLAVAVTTPADLAARVAIVRRRDAYERDPAGFAAEWAGEEERLAGAILAARARLPRVAVPDEVLEAAARLCLALGTDGLRGELTLMRTARALASLDGDEAVGLAHLREVAPAALGHRLRRNPLDEAGAEARVARAVAEVLG
>NC_010511.1|WP_012333509.1|4160066_4161278_+|5-aminolevulinate-synthase
MDYESFFAAQLQGLHREGRYRVFTDLERQAGRFPYATQHGAHGTREVTVWCSNDYLGMGQHPAVAAAMHEAIDRCGAGAGGTRNISGTNHYHVLLERELADLHRKEAALLFTSGYVSNWAALGTLASRLPGCVVFSDEGNHASMIEGLRASRAERHIFRHNDPADLDHKLRLVNPALPKLVAFESVYSMDGDVAPIAELCDVAEAHGAMTYLDEVHAVGLYGPRGGGIAEREGLMDRLTVIEGTLGKAFAVSGGYIAASAALCDFVRSFASGFIFTTSLPPAVAAGAAASIRHLKASGAERARHQDRVAAVRRRLGALGIPVMANESHIVPVMVGDPVLCKQISDTLLDEFAIYVQPINYPTVPRGTERLRITPSPLHSDADIEHLAAALGAIWARIGLARAA
>NC_010511.1|WP_012333508.1|4159212_4160019_+|DUF3623-domain-containing-protein
MSAYASPILFAVLMWWFLTGAILWLNHRPRHTHAWSFGAMSLALLLALWGIAATAGAESEASAYGAFSAALVVWGWQEMAFYMGYVAGPRRTPGPPSIRGLARFGAAAATNLWHEAAIVAGAAAIAWLTAGAPNRIALWTYLVLWGMNLSARLNLFLGVRNLHAEFLPEHLRYLGSFFRRAPMNALFPVAMLLATGFLLVLLHPAVTESASAFKRSGHTMLATLMALAILEHGFLMLPLPSAALWAWGLPARRPPDPDTGPRPAGDIA
>NC_010511.1|WP_012333507.1|4158146_4159208_+|magnesium-protoporphyrin-IX-monomethyl-ester-(oxidative)-cyclase
MTATALPAQNESTRAAQATTFLSPRFYTTDFAELDRTDVEPVRAEWDVLIAEMRADPNRRHFVRNTEFDLDLSGLDPELRKEFLDFLVSSITAEFSGCVLYAEMRKRAKNKDIRELFAFMSRDEARHAGFINDTLKDFGVGVDLGFLTRAKKYTYFRPKFIFYATYLSEKIGYARYITIFRHLERHPENRFHPIFKWFEKWCNDEFRHGEAFALLMRANPKLLSGLNAYWIKFFVLAVFATMYVRDHCRPAFHGALGVDPTDYDFAVFRVTSEISRQVFPLTLDLDNPAFKAGLDRLLACARGIEAAKAQGGLAGRLRRAGHAARAALTFGRLLLLPSKPNPMPEQIRLSPAW
>NC_010511.1|WP_036270252.1|4157847_4158150_+|hypothetical-protein
MIPWLTTKRRIEVPCTVEIEQTPESLHAHVTLEGGLAIEPGDEVTVHDAPTSVPYGTRLTVRRRATVLRASALERAWTRLAGHFELTELYEVSFTERTTL
>NC_010511.1|WP_012333516.1|4168319_4169603_+|ArgE/DapE-family-deacylase
MPLDPALRDRIIASVEAGFPDQIAHTQALVRFPSTRGQEQAIQDFVFRAFRARGLAMDRFAMDRAAIEDHPGGSKFAPDHSEAPIVVGIHRPRAETGRSLILQAHVDVVPPGPIDLWTHPPFEPVIEGDWLYGRGGADMKAGHAANLFVLDALTRIGLQPAATVTLQSVVEEESTGNGALMTHLRGYRAEAVLIPEPEEEMLVRANTGVLWFQVEVRGRPVHVREMGTGANAIDAAYRVIGALRRLEESWNARKAGRRHFEGEAHPINLNVGRIEGGDWASSVPAWCRIDCRIAIYPGVGAEEAAREIEAAVHAFALADPFLSNAPPRVTFNGFFAEGYELAEGSEAEAVLAWAHEAATGRALRSFMTAGYLDTRVHALYDRVPALCYGPISENIHGFDERVSLASLKRITIAMALFVAEWCGVEPV
>NC_010511.1|WP_012333517.1|4169795_4171883_-|transketolase
MSAAETAAKAGISAIDQRSIDTIRTLTMDAVQKANSGHAGAPMALAPVAFTLWNRYLRYDPAHPTWPNRDRFVLSVGHASMLLYSLLHLAGVAQKDGADEPAVSLDDIKRFRQLDSRTPGHPEYHFTTGVEVTTGPLGQGVANSVGMAMGARFLNERFPFGERAVFDFNVYALCSDGDLMEGVASEAASIAGHLRLANLCWIYDSNTVTIEGHTDLAFSEEVATRFLAYGWQVLRVADANDVPALAGAIETFLQSQDRPTLIIVNSVIGYGAPTKQGTSKAHSDALGVEEIRGAKRFLGWPEDAEFLVPDGVYENFRQGIGARGAALFSEWQELMEEVRASDADLAGAVSSFLSGELPAGWDAAIPHFPADAKGLATRESSGKVLNAIAAKVPWLLGGSADLAPSNKTRIEGEEALGPFTPGGRNIHFGVREHAMGSIVNGLGLVGLRAYGATFLVFSDYMRPPIRLAALMELPVFHVFTHDSIGVGEDGPTHQPVEHLLSLRSIPGLITLRPADANEVAEAYRVIMGLRHQPAVLALSRQPLPTFDRATCAPASGLARGAYVLAGGEGTPELILIGTGSEVQLCLGAYETLRGEGVRARVVSMPSWELFEQQDAAYRESVLPPAVTARVVVEQGSVIGWDRYAGSAGTILGMHTFGSSAPIKDLQTKFGFTSAKVLEAARAQLARAKGLARAKG
>NC_010511.1|WP_012333518.1|4171900_4173742_-|glycoside-hydrolase-family-15-protein
MASRIEDYALVGDGRSAALIGRDGSIDWLCWPRFDAPACFAALLGTAEHGHWRIAPAGPATRVTRCYRPGTLVLETTHETEAGTIRVTDYMPSDDGLHLVRLVEGVSGSVPVRMEFVVRFDYGSAVPWVSRNEHDDLRAIVGPHKVVLRTKAPLRGVGRSTVSDFTLAQGECLSFVLSYAPSAEDDPAPIEPRKVLRRTTDAWRSWSSRCQGGTPWDDILLRSLLTLKALIYAPTGGIVAAPTTSLPEALGGVRNWDYRYCWLRDSTFTLLALVDAGYLDEARAWRDWLLRAVAGSPEQARILYGIAGERLLPEIEIDWLPGYEGSRPVRIGNAASQQFQLDVYGEIFDALYQAEERGMEGDDNGVRVGLALLAHLEKVWTEPDEGIWEVRGGRRHFVHSKVMAWVAFDRAVRFYERLNGDGAGDATVARWRDVRARIHAQVCERGFDPELNSFVQSYGSKRLDASLLLIAHVGFLPHHDPRVVGTVEAIGRDLMRDGFILRYDTENQTTDGLPAGEGAFLPCSFWYADNLIRLGRCAEARAMIERLLAACNDVGLLAEEYDPVAKRQVGNFPQAFSHVALVNTLLNFSRAVGPAMERSDDEGRGAAGATART
>NC_010511.1|WP_012333519.1|4173814_4174468_-|hypothetical-protein
MSEFDGRREAAPGSVDGGRTLGYLPLLPTLCVAACLAAGSLYWRDAPPRPPAGQAAAAAPRPVPDPFRTAEAGGEALTRHPLPLEFARQFPLAVSSALAAEARAPAEPAAAGPLCEALPAAAPEKPLPLSARPAPRRPASPRHALQAAQARPSRPAALQAAEAGPEETPPTERASFAGLALPRVVETGRVMVRHVSALGAGVVQAGSAMLDLIDRHP
>NC_010511.1|WP_050777495.1|4174742_4175363_+|ANTAR-domain-containing-protein
MPDPVTNAPLTSPDQSLTIAVVDPSRARAAVLEEGLRNLDGARVVVIPDTVDLLDRLSALAPDVVVIHLESPSRDLLEQLFGVSRLVEKPVAMFVDRSDTAMMQAAVDAGISAYIVDGLKADRIKPIIEVAILRFNAFARLQRELAEARNELADRKLIDRAKGILMSAKGLSEDEAYKQLRRKAMNEKRKIVDIARAIVTAADLLG
>NC_010511.1|WP_012333521.1|4175359_4176364_+|ABC-transporter-substrate-binding-protein
MRFQLGYVPLTDAATVIAMAEGGFAAREGLRVELVAEPSWATLRDKLALGLLDGAHILAPLALASHLGLSGPPASLIAPAALGRNGNAVTLSLPLWEAMRPDGEALPEVARALAALAGARAAAGRPLTLGTVHPFSSHTYQLRRLLALGGCRLDQVRLVAVPPPRTVESLRRGLIDGFCVGAPWNSVAVEAGVGRIAALGVDLAPDCPEKVLALPAELEERAPPLLRALRAAARWCGEPGNRPDLARMLAAPRHLGLDPDLILRGLAGSLQLAPRGAAPRAAPDYLTLGEEVLAFDMGAIDWILAEMEACGQFAAPPAARAQAAALPRPDLLAA
>NC_010511.1|WP_012333522.1|4176864_4178160_+|ABC-transporter-substrate-binding-protein
MSIGRGDHTTRRGLLKGAAAALSLTAAARAALPGGAFAQGTGPEVKGAKLGFIALTDAGPLFVAKEKGFFAKHGMPEVEVLKQASWGTTRDNLVLGSEGNGIDGAHILTPMPYLISAGRVTQNNVPVPMHILARLNLNGQCISVAKEYLDAKVALDSKVFRVATDKKKAAGKSVKAAMTFPGGTHDLWIRYWLAAGGIDPDRDIETIVVPPPQMVANMKVGTMDCFCVGEPWNAQLVQQGLGYTALTTGELWKDHPEKAFAMRADWVQKYPNATRALLMAVIEAQQWCDRPENRDEFAAIVAKRQWINIPVGDVAGRMKGTIDYGDGRVVKDSPFVMKFFRDHASYPFQSHDLWFLTEDIRWGKFEPQTDTRALIAKVNREDLWREAAKALGVSAIPASTSRGRETFFDGKVFDPADPAAYLSSLSIKKVA
>NC_010511.1|WP_012333523.1|4178159_4179026_+|nitrate-ABC-transporter-permease
MALGTSIGGLAAARRKGEASRGPLVTAAGLRALAARIVPPLVVLGLFLLVWQVLCDRPGAGLPAPSRVMSEAWPIISDPFFDNGGTDKGLFWHIVASLQRVALGFALASVAGVLLGTLVGQSEWAMRGLDPIFQVLRTIPPLAWLPLSLAAFRDGQPSAIFVIFITSIWPIIINTAVGIRNIPQDYRNVASVLRLNAFEFFGKIMLPSAAPYIFTGLRIGVGLSWLAIVAAEMLIGGVGIGFFIWDAWNSSHISEIIVALVYVGVIGFVLDRVVAGIGQLVTRGTASA
>NC_010511.1|WP_012333524.1|4179039_4179834_+|ABC-transporter-ATP-binding-protein
MSHLVLSNVGISFTRAGRTTEVLRDVNLSIAKGEFVSLIGHSGCGKSTVLNIVAGLLRASTGGVLLDDREVNSPGPERAVVFQNHSLLPWLTVRENVALAVDKVLRARKGRAERRDWVAHNLALVNMTHAAEKRPHEISGGMKQRVGIARALAMEPKVLLMDEPFGALDALTRAHLQDQLMEIHLRLRNTVIMITHDVDEAVLLSDRIVMMTNGPSATIGEVLAVPLARPRRRLDLVEDPTYTHARAEVLEFLYARHAKPALAA
>NC_010511.1|WP_012333525.1|4179844_4181062_+|NAD(P)/FAD-dependent-oxidoreductase
MQERLVVVGNGMASLRFLERLTERQGGRYAVTVVGAEPVAAYNRVLLSSLLGGEVDEAACTFRGLDWYADHGITLVTGAPATAIDRESRTVRVGEGLVLPYDRLVLAVGSVPIRLPRPGMDLPGIVTFRDLADVAAIRRAAAPGARAVVIGGGLLGLEAAVGLARLGAETTLLHVMDRLMERQLDHAAADLVRRAIEARGVRVRLGADTAAVEGEGRVEALRLADGATIPADLVVLSVGVRPSTSLAAASGLAVGRGIRVDDRMTTSDPSVFALGECAEHRGMTYGLVEPAYEQAEVLARHLCGEAAAYAGTALSTSLKVSGLPVFSAGLVDVPEGAEAVTWSDPAAGLYRKLVIAENRLLGAVFVGDVAEQGWCKALIRSGERLARADRDDLIFGRPAPQPLAA

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Crispr_ID: NC_010511_25

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_010511_25

4213536-4213631

Orphan

Consensus_repeat	Method
TCGCTCACGCGCCGCGCGGGCTTGGCA	CRISPRCasFinder

1 spacers

The CRISPR arrays of NC_010511_25

>merge|NC_010511|25|4213536-4213631|CRISPRCasFinder
TCGCTCACGCGCCGCGCGGGCTTGGCATACCCAATCCGCTCGATCCCTTCGGGATGGCGGATTGGGGCTTCGCTCACGCGCCGCGCGGGCTTGGCA

>NC_010511|25|25|4213536-4213631|CRISPRCasFinder
TCGCTCACGCGCCGCGCGGGCTTGGCA	TACCCAATCCGCTCGATCCCTTCGGGATGGCGGATTGGGGCT
TCGCTCACGCGCCGCGCGGGCTTGGCA

Protein	Signature genes	Signature genes Name	Protein_function
NC_010511.1\|WP_012333565.1\|4219992_4220433_-\|DUF202-domain-containing-protein	unknown	unknown	gnl\|CDD\|376882
NC_010511.1\|WP_012333553.1\|4210763_4211225_+\|YidB-family-protein	unknown	unknown	gnl\|CDD\|226276
NC_010511.1\|WP_012333566.1\|4220462_4221755_-\|DUF2183-domain-containing-protein	unknown	unknown	gnl\|CDD\|227187
NC_010511.1\|WP_012333560.1\|4215610_4215799_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|377536
NC_010511.1\|WP_012333554.1\|4211258_4211630_-\|nuclear-transport-factor-2-family-protein	unknown	unknown	gnl\|CDD\|378915
NC_010511.1\|WP_012333548.1\|4206582_4207470_+\|transporter-substrate-binding-domain-containing-protein	unknown	unknown	gnl\|CDD\|270222
NC_010511.1\|WP_012333559.1\|4215048_4215318_+\|hypothetical-protein	unknown	unknown	unknown
NC_010511.1\|WP_012333550.1\|4208962_4209196_+\|hypothetical-protein	unknown	unknown	unknown
NC_010511.1\|WP_012333547.1\|4204566_4206465_-\|glycosyltransferase	unknown	unknown	gnl\|CDD\|133049
NC_010511.1\|WP_012333557.1\|4213666_4213978_-\|hypothetical-protein	unknown	unknown	unknown
NC_010511.1\|WP_012333552.1\|4210436_4210709_+\|hypothetical-protein	unknown	unknown	unknown
NC_010511.1\|WP_012333561.1\|4215944_4216157_-\|hypothetical-protein	unknown	unknown	unknown
NC_010511.1\|WP_012333558.1\|4213974_4214628_-\|SGNH/GDSL-hydrolase-family-protein	unknown	unknown	gnl\|CDD\|238141
NC_010511.1\|WP_012333563.1\|4218553_4218802_+\|hypothetical-protein	unknown	unknown	unknown
NC_010511.1\|WP_012333562.1\|4216424_4218335_-\|glycosyl-transferase	unknown	unknown	gnl\|CDD\|273955
NC_010511.1\|WP_012333549.1\|4207491_4208139_+\|glutathione-S-transferase	unknown	unknown	gnl\|CDD\|182533
NC_010511.1\|WP_012333551.1\|4209264_4210440_+\|aminotransferase-class-V-fold-PLP-dependent-enzyme	unknown	unknown	gnl\|CDD\|223594
NC_010511.1\|WP_012333556.1\|4212228_4213275_+\|YihY/virulence-factor-BrkB-family-protein	unknown	unknown	gnl\|CDD\|224214
NC_010511.1\|WP_012333555.1\|4211642_4212131_-\|OsmC-family-protein	unknown	unknown	gnl\|CDD\|376823
NC_010511.1\|WP_050777576.1\|4218822_4219854_+\|Holliday-junction-branch-migration-DNA-helicase-RuvB	unknown	unknown	gnl\|CDD\|234619

Protein	Function_ID	Function_description	E-value
NC_010511.1\|WP_012333553.1\|4210763_4211225_+\|YidB-family-protein	gnl\|CDD\|226276	COG3753, COG3753, Uncharacterized protein conserved in bacteria [Function unknown].	5.85124e-26
NC_010511.1\|WP_012333566.1\|4220462_4221755_-\|DUF2183-domain-containing-protein	gnl\|CDD\|227187	COG4850, COG4850, Uncharacterized conserved protein [Function unknown].	6.15139e-55
NC_010511.1\|WP_012333556.1\|4212228_4213275_+\|YihY/virulence-factor-BrkB-family-protein	gnl\|CDD\|224214	COG1295, Rbn, Ribonuclease BN family enzyme [Replication, recombination, and repair].	2.55268e-57
NC_010511.1\|WP_012333554.1\|4211258_4211630_-\|nuclear-transport-factor-2-family-protein	gnl\|CDD\|378915	pfam12680, SnoaL_2, SnoaL-like domain. This family contains a large number of proteins that share the SnoaL fold.	1.61513e-05
NC_010511.1\|WP_012333548.1\|4206582_4207470_+\|transporter-substrate-binding-domain-containing-protein	gnl\|CDD\|270222	cd01001, PBP2_HisJ_LAO_like, Substrate binding domain of ABC-type histidine/lysine/arginine/ornithine transporters and related proteins; the type 2 periplasmic-binding protein fold. This family comprises the periplasmic substrate-binding proteins, including the lysine-, arginine-, ornithine-binding protein (LAO) and the histidine-binding protein (HisJ), which serve as initial receptors for active transport. HisJ and LAO proteins belong to the type 2 periplasmic-binding fold protein (PBP2) superfamily, whose members are involved in chemotaxis and uptake of nutrients and other small molecules from the extracellular space as a primary receptor. PBP2 typically comprises of two globular subdomains connected by a flexible hinge and bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap. After binding their specific ligand with high affinity, they can interact with a cognate membrane transport complex comprised of two integral membrane domains and two receptor cytoplasmically-located ATPase domains. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis.	8.42014e-67
NC_010511.1\|WP_012333555.1\|4211642_4212131_-\|OsmC-family-protein	gnl\|CDD\|376823	pfam02566, OsmC, OsmC-like protein. Osmotically inducible protein C (OsmC) is a stress -induced protein found in E. Coli. This family also contains a organic hydroperoxide detoxification protein that has a novel pattern of oxidative stress regulation.	1.8509e-17
NC_010511.1\|WP_012333547.1\|4204566_4206465_-\|glycosyltransferase	gnl\|CDD\|133049	cd06427, CESA_like_2, CESA_like_2 is a member of the cellulose synthase superfamily. The cellulose synthase (CESA) superfamily includes a wide variety of glycosyltransferase family 2 enzymes that share the common characteristic of catalyzing the elongation of polysaccharide chains. The members include cellulose synthase catalytic subunit, chitin synthase, Glucan Biosynthesis protein and other families of CESA-like proteins. Cellulose synthase catalyzes the polymerization reaction of cellulose, an aggregate of unbranched polymers of beta-1,4-linked glucose residues in plants, most algae, some bacteria and fungi, and even some animals. In bacteria, algae and lower eukaryotes, there is a second unrelated type of cellulose synthase (Type II), which produces acylated cellulose, a derivative of cellulose. Chitin synthase catalyzes the incorporation of GlcNAc from substrate UDP-GlcNAc into chitin, which is a linear homopolymer of beta-(1,4)-linked GlcNAc residues and Glucan Biosynthesis protein catalyzes the elongation of beta-1,2 polyglucose chains of glucan.	6.42235e-120
NC_010511.1\|WP_012333558.1\|4213974_4214628_-\|SGNH/GDSL-hydrolase-family-protein	gnl\|CDD\|238141	cd00229, SGNH_hydrolase, SGNH_hydrolase, or GDSL_hydrolase, is a diverse family of lipases and esterases. The tertiary fold of the enzyme is substantially different from that of the alpha/beta hydrolase family and unique among all known hydrolases; its active site closely resembles the typical Ser-His-Asp(Glu) triad from other serine hydrolases, but may lack the carboxlic acid.	2.2298e-06
NC_010511.1\|WP_012333565.1\|4219992_4220433_-\|DUF202-domain-containing-protein	gnl\|CDD\|376882	pfam02656, DUF202, Domain of unknown function (DUF202). This family consists of hypothetical proteins some of which are putative membrane proteins. No functional information or experimental verification of function is known. This domain is around 100 amino acids long.	6.54664e-08
NC_010511.1\|WP_012333549.1\|4207491_4208139_+\|glutathione-S-transferase	gnl\|CDD\|182533	PRK10542, PRK10542, glutathionine S-transferase; Provisional.	1.91893e-31
NC_010511.1\|WP_012333551.1\|4209264_4210440_+\|aminotransferase-class-V-fold-PLP-dependent-enzyme	gnl\|CDD\|223594	COG0520, csdA, Selenocysteine lyase/Cysteine desulfurase [Posttranslational modification, protein turnover, chaperones].	7.75968e-45
NC_010511.1\|WP_012333560.1\|4215610_4215799_-\|hypothetical-protein	gnl\|CDD\|377536	pfam05638, T6SS_HCP, Type VI secretion system effector, Hcp. HCP is a family of proteins which are expressed in up to 1000 copies in Gram-negative bacteria. Together these copies aggregate into a needle-like shaft or tube that will penetrate other bacteria via a puncturing protein attached to its head. Initially Hcp forms a hexameric structure with a central channel of 40 Angstroms. These hexamers pile up one on top of each other forming nanotubes resembling the gp19 tail phage tube.	3.45082e-07
NC_010511.1\|WP_012333562.1\|4216424_4218335_-\|glycosyl-transferase	gnl\|CDD\|273955	TIGR02074, Includes:_Penicillin-insensitive_transglycosylase, penicillin-binding protein, 1A family. Bacterial that synthesize a cell wall of peptidoglycan (murein) generally have several transglycosylases and transpeptidases for the task. This family consists of bifunctional transglycosylase/transpeptidase penicillin-binding proteins (PBP). In the Proteobacteria, this family includes PBP 1A but not the paralogous PBP 1B (TIGR02071). This family also includes related proteins, often designated PBP 1A, from other bacterial lineages. [Cell envelope, Biosynthesis and degradation of murein sacculus and peptidoglycan].	5.74238e-120
NC_010511.1\|WP_050777576.1\|4218822_4219854_+\|Holliday-junction-branch-migration-DNA-helicase-RuvB	gnl\|CDD\|234619	PRK00080, ruvB, Holliday junction branch migration DNA helicase RuvB.	0

>NC_010511.1|WP_012333556.1|4212228_4213275_+|YihY/virulence-factor-BrkB-family-protein
MATDDEGGQDWRSVGTRRPDAAERERALARAREPGRGRTAAQPSEIPSRGWGDILWRVAWSVPQDRVLATAGGVAFFALLAVFPGLALIVSLYGLVADPGAIYKHLSLLTGLLPQAVLDLLAAELSRVAGKSTGALGAASGVSLLVAFWSANSGVSALFDALNVIYKEREKRPLLHFYATTFLFTLTGVLFALVATGMVVALPVVLNQVGFQSYASDAALRLLRWPALLVLVSLGLAAIYRYGPSRHEAKWRWVTWGSGIAALLWVCASALFSWYVARFDSYNRMYGSLGAGVGFMTWIWFSIVIVLLGAELNAEMERQTVRDSTTGRPKPLGTRDAHAADTVGPSHE
>NC_010511.1|WP_012333555.1|4211642_4212131_-|OsmC-family-protein
MPDPFDVSLKHLKGYQFLVDFGTGLPDLLTDEPNPIGTGEGPSPEQMLTAAVANCLCGSLVFALGKYRQEVRGLGATARCRVARNAEGRLRVEAIDVEIVLALEAVQADRLDKVLSQFRKFCTVSESVEAGVPVRVTLRDGAGGRLAWPAGDPPAEAGRSTP
>NC_010511.1|WP_012333554.1|4211258_4211630_-|nuclear-transport-factor-2-family-protein
MQDTDRERAAEPEALTRLFLARANAGDVEGLVALYAPEAVLAVGEVVARGHEEIRRFYEGLLRKRSHFPPVETLPVIRTGPVALTMARSGRGSLSVEVARQGEDGAWLWVIDQLKVEAGPRQE
>NC_010511.1|WP_012333553.1|4210763_4211225_+|YidB-family-protein
MSDGYPSMTALLGLLALAGYQNRDKLAEMFGGGAQTAPAPAPAGQGGGLGGFLGGLGAGGGGGGPGGFLHSGLGEMLERFQQAGQGPVAQSWVGHGPNQPISPQQLEQAIGPDVLQVLAQRTGLPREELLERLSRDLPQAVDRYTPDGRVPSY
>NC_010511.1|WP_012333552.1|4210436_4210709_+|hypothetical-protein
MRFAGTAAAAIVVSALGIGAAEAKGCIKGAIIGGVAGHYLANRGVVGAVAGCLGGRYIASRNARREVDYGARVAPGGYGPGRPPRRDYNY
>NC_010511.1|WP_012333551.1|4209264_4210440_+|aminotransferase-class-V-fold-PLP-dependent-enzyme
MTEPLPCQRPLFEIPDAVSYLDAAAWSPIPRPVREAGEAGMLTKVRPWAHPRERAAGWAEEARAAAAALIGAGPADVAIVGSVSHAMATAARNLSPPPGSRVLRVADEFPSHRYAWDRLAQARGLVVEEVARPEDGDWTAALARAIARPGAPPVGVATLTPLHWADGALIDLDRLAPALREAGAALVVDATQAAGAVPIDVARLRPDFLAFPTYKWALGPYSLAFLYAAAHRQDGVPLEENSGNRPQAAAGARRYDRGERDDPVALPMAAAGMGLIAGWGVAGVAARLRALTDLLAEGCAALGLPVPPRALRAPHILGIHLPGDEAERLVAFLRERQVFASARLGRLRLSPHVWADEADIARFLHALRDGVAGGTEGRAGRSPALTDRRAE
>NC_010511.1|WP_012333550.1|4208962_4209196_+|hypothetical-protein
MGIVEQRERAQQAWAFALEHLVSKGCDEAVALETMSEVAFQTYVDRHGSVATASYLRLLAQQVEEADREFAAALMQG
>NC_010511.1|WP_012333549.1|4207491_4208139_+|glutathione-S-transferase
MTETLRLYYSPGACSLAPHVALEETGAPFEPVRVNLAAGEQRQASYLAINQKGRVPALAEGAWVLTENPAVLRYIARRFPEAGLWPEDPRGEAACAEWLAWLASTVHVAYAHVRRAERYAGEEAAIAEVQARGREACFDLWTMIEVGLSRGGWALGERYSVADPYLLVFWIWGRGPALGYEMARLFPHWTAHARRMAARPAVQRVFAREGLALPA
>NC_010511.1|WP_012333548.1|4206582_4207470_+|transporter-substrate-binding-domain-containing-protein
MTQGKRWTRLVSAPNLAPVLAPVLAPVLALALWCGAGRAAEPVTIPNFWNPRARLERPEPPQTSRAVRFITDDEYPPLHFAGPDGNPTGFSVELARAACEKLNLTCTVQARRFDTLLDALAAKEGDVVAAAIPLTPALRANFLATRPYFRWPARFVVRADKGLPAPDAKALATRSVGVVAGTAHEAYLKAFFRTTPRGFPDLGTAQAALKRGEIDYLFADGVALALWLGGVDAAGCCAFAGGDYLENRYFGEGIGLVTRKEDEVLARALDDALQRLWDEGKYAELYLRFFPVSPF
>NC_010511.1|WP_012333547.1|4204566_4206465_-|glycosyltransferase
MPFAVPAAAHADVRPELSFLRAEGVPLDVLTLAGWIARCSGTDGATALIRSGLMSEEAYYRALARALGAPYLAGAIALGPGARYPESILAGVAPLPPGGGPALVRAPRGAEIGHLLAGGARAGSGIAITAPGQLRAAVLEACAPQAARQASEALQRAAPDWAYRPGPSPGQCLAACLALAAVPLLWDAPGSVQGAAAAAVSLLFLGMTVFRLAALLVPPCPLPDLPRAEDADLPVYTVLVALSREAAIVPDLIAALARLDYPATKLDAKIVIEADDAETAGALAARALPPWIEVIVAPPGEPRTKPRALNVALPLARGTYLAVYDAEDEPHPLQLRAAAALFARTSPRTACLQGRLVVDNAEQSWLTRCFALEYAALFDVLVPALAAWRLPIALGGTTTHFRTEALRAVHGWDAWNVTEDADLGLRLSAAGYRVGDLPLPTGEEMPSRPGRWLRQRTRWMKGFVQTTITHARRPVATARALGVLGTLAALALVPGAVVSALVYPAALLVAGWRLLVQPAEPDPSFWTNMVTALGIELFGAGFAAIALPALLGCLRRGRPDLIPWIAALPAYYVLVSLGAWLGLAEFFVAPFRWNKTEHGLARAARRRRRASTASELAGELRRGIRRRPHQVE
>NC_010511.1|WP_012333557.1|4213666_4213978_-|hypothetical-protein
MSATLVQILLPLSDNEGRPFPGSAYAGVRDELAGTFGGVTAYSRGPAEGVWQDGKGRSHDDIVVFEVMCDDLDPAWWARYRRELEARFRQDSIVVRAQAIRLL
>NC_010511.1|WP_012333558.1|4213974_4214628_-|SGNH/GDSL-hydrolase-family-protein
MHHVVLLGDSVFDNAAYVGGGPDVVRQLRAALAPEGRATLCALDGAVLADVARQLAGVPPDGTHLVVSAGGNDALRASALLVRPAGSVAEAVGALADARDGFRAQYRAMLDAVLARGTPTCLCTIYDPRYADPAYRRVASAALAVLNDVVTREAWARDLPLIDLRVLCDEDADFANPIEPSVRGGEKIAAAIAALVRGEPVRRAPRRSGPERGDASR
>NC_010511.1|WP_012333559.1|4215048_4215318_+|hypothetical-protein
MTRERSVTTGDGTAWTCLEAYAGLAETADRAETADRALATRRDDGRRAVVCTPSGGAHSVRLSLPAGWEEDVADADLAAAIEAQHPREP
>NC_010511.1|WP_012333560.1|4215610_4215799_-|hypothetical-protein
MHREQPTPRPRRDELRDDALDHVAGGAGSQQAPVGARPTGAGAGRATFTPFTITRLNDKATP
>NC_010511.1|WP_012333561.1|4215944_4216157_-|hypothetical-protein
MPNRSYIVRKTHDGWSVHAAKTNEPVRLNGREQTGMSREAAAELANSLEMLAVVQEFRDERPVTNPYTLH
>NC_010511.1|WP_012333562.1|4216424_4218335_-|glycosyl-transferase
MRRSVGLALLCAAALAGPARAETPETPSFWDLKPAELRALVAAPQVMVTRTATGFDAYCRCPVVLRPNEIPEAMKKAIIAVEDRRFLEHGGVDLIALAAVLRGGLSRGGSTIPMQLLKNLVFHDLQGRDFLSKLERKGSEVWHAGTFDGAVGKQELLAAYLNQIEFGGREIVGLYRASRHYFGKEPRDLTLFECALLAGMVQAPARFNPLREATRERAYARARLVLRLMVEQGRISEAERLRAERTGVRPGSMPDFAIQAQPFTEWVVQSFAPRTMQEGETLRFFVTLDPRFQQAAEARLAEMAGSGAIPPAYEAGAVMMSPDGRVRAMIGSLDWARRPFNAAVKTSVQPGSTAKLPLLVAACEAGLSPESRVLDLPLTDTWPSNGHLGYRGETTLLEAVASSRNAASVRLAREIGVPRVAEASRRLGLDPGPNPDAGFVLGSYATSVMAVTAAYAAIANGGYRVAPTGVLAVVDGRGQVRARFLDPARARAVPARCIPPTRRILREVVRSGTGRNAGLGSREAYGKTGTSTGNADAWFVGWSEGRVLGVWMGRRRDAAGEVLAGKDAPAAYFRRVETSVSEIVEARAGRARGPAREPPPGRVAAGPRRAAEARLSPPARPAPGPRAPLPLPWEPW
>NC_010511.1|WP_012333563.1|4218553_4218802_+|hypothetical-protein
MARYRFHCTNGAECVLDTVGAEVRAPARLTARAAETARAVMGALGERADWSQWRVSVHDLTGRRVLTRPFLAAGCGPAAVAA
>NC_010511.1|WP_050777576.1|4218822_4219854_+|Holliday-junction-branch-migration-DNA-helicase-RuvB
MAGSRLAPITEAGEVPDGSIRPLSLSDFTGQRAARANLGVFIEAARRTGQALDHVLFVGPPGLGKTTLAQIVARELGVNFRSTSGPVIAKAGDLAAQLTNLEERDVLFIDEIHRLNPAVEEILYPAMEDYQLDLIIGEGPAARSVKIELPRFTLVAATTRAGLLTTPLRDRFGIPIRLEFYAVDELEAIVARGARVLGIGMAADGANEIARRARGTPRIAGRLLRRVRDFAIVEEAGTVTRAIADRALRLLDVDAAGLDTMDRKYLGLIARSYGGGPVGVETIAAALSEPRDAIEEIIEPYLLQQGFVQRTPRGRLLTPHAFRHLGLPVPVREEEPLDAALPE
>NC_010511.1|WP_012333565.1|4219992_4220433_-|DUF202-domain-containing-protein
MEQATGSERRTEQAAERTAAAAQVTKDSADRRTELAADRTVFAAERTYAAWMRTGLVALASGIGARKLLEGVVPGWMIVGFGTILVLFSAFCFVAGVWRQVFVGAPPPRPDVPRLPPAILVAVNGFLALVALAALLGLWFGRALGA
>NC_010511.1|WP_012333566.1|4220462_4221755_-|DUF2183-domain-containing-protein
MTGARAGRLRRAAGWILGLAARPVRRAQGRRGVAVEVYRGYGSAQEIFLIGRAFRQSEAERAADPDDLRAQLRDIGRRIRRRRLPGLAVEARFGGSAARTVTDRDGYFRIHLCPRPPGPGEGAWHPVSIRLASDPPVEARGEVFIPPPRCRFVVISDIDDTVMHTGVANKLKMLWRLFVADATRRVAFPGVAALYRALHAGAGGAEQNPMLYVSRAPWGIYDMLSEFFRLHDIPVGPVLFLREWGLSWRHPLPRRAEDHKAELIRRMLVLYRDLPFVLIGDSGQHDPEVYAGIVHAHPGRVLAVYIRNVSRAPERAAEIARLAREVAAAGSSLVLAADSRAIAAHAAGLGLIAAPAVEAVASEKAAAEGATRPRRPRRITRPTPEATATAASGEAVEAALGGTSPEPPTVIVEPAGRGEAGDGAQGPAER

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Crispr_ID: NC_010511_26

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_010511_26

4322263-4322341

Orphan

Consensus_repeat	Method
TAGATGTACCGGAAGTGGTACTGGAGA	CRISPRCasFinder

1 spacers

The CRISPR arrays of NC_010511_26

>merge|NC_010511|26|4322263-4322341|CRISPRCasFinder
TAGATGTACCGGAAGTGGTACTGGAGATTCCCGGTACCGGAAGTGGTGGTACTAGATGTACCGGAACTGGTACTGGAGA

>NC_010511|26|26|4322263-4322341|CRISPRCasFinder
TAGATGTACCGGAAGTGGTACTGGAGA	TTCCCGGTACCGGAAGTGGTGGTAC
TAGATGTACCGGAACTGGTACTGGAGA

Protein	Signature genes	Signature genes Name	Protein_function
NC_010511.1\|WP_012333653.1\|4330446_4331619_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|274008
NC_010511.1\|WP_012333640.1\|4318807_4319359_+\|cupin-domain-containing-protein	unknown	unknown	gnl\|CDD\|182158
NC_010511.1\|WP_012333651.1\|4326444_4326639_-\|hypothetical-protein	unknown	unknown	unknown
NC_010511.1\|WP_150108695.1\|4321233_4321446_-\|MerR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|133393
NC_010511.1\|WP_012333649.1\|4324121_4325264_+\|site-specific-integrase	unknown	unknown	gnl\|CDD\|271189
NC_010511.1\|WP_012333635.1\|4312138_4312924_-\|ABC-transporter-permease	unknown	unknown	gnl\|CDD\|224098
NC_010511.1\|WP_150108696.1\|4321417_4321816_-\|hypothetical-protein	unknown	unknown	unknown
NC_010511.1\|WP_150108697.1\|4326650_4327229_-\|hypothetical-protein	unknown	unknown	unknown
NC_010511.1\|WP_043701399.1\|4320672_4321143_-\|hypothetical-protein	unknown	unknown	unknown
NC_010511.1\|WP_012333652.1\|4329342_4329942_+\|cysteine-hydrolase	unknown	unknown	gnl\|CDD\|238496
NC_010511.1\|WP_043701402.1\|4323168_4323417_-\|DNA-binding-protein	unknown	unknown	gnl\|CDD\|378935
NC_010511.1\|WP_012333646.1\|4322917_4323172_-\|hypothetical-protein	unknown	unknown	unknown
NC_010511.1\|WP_043701396.1\|4320409_4320631_+\|DUF3606-domain-containing-protein	unknown	unknown	gnl\|CDD\|371985
NC_010511.1\|WP_012333638.1\|4316662_4317268_+\|helix-turn-helix-domain-containing-protein	unknown	unknown	gnl\|CDD\|380339
NC_010511.1\|WP_012333648.1\|4323429_4324002_-\|hypothetical-protein	unknown	unknown	unknown
NC_010511.1\|WP_012333645.1\|4322372_4322921_-\|hypothetical-protein	unknown	unknown	unknown
NC_010511.1\|WP_012333650.1\|4325411_4326461_-\|tyrosine-type-recombinase/integrase	unknown	unknown	gnl\|CDD\|271181
NC_010511.1\|WP_150108854.1\|4313768_4316273_-\|FAD-dependent-oxidoreductase	unknown	unknown	gnl\|CDD\|223481
NC_010511.1\|WP_012333636.1\|4312920_4313772_-\|ABC-transporter-permease	unknown	unknown	gnl\|CDD\|224097
NC_010511.1\|WP_012333639.1\|4317324_4318662_-\|aspartate-aminotransferase-family-protein	unknown	unknown	gnl\|CDD\|181707

Protein	Function_ID	Function_description	E-value
NC_010511.1\|WP_012333653.1\|4330446_4331619_+\|hypothetical-protein	gnl\|CDD\|274008	TIGR02168, Chromosome_partition_protein_Smc, chromosome segregation protein SMC, common bacterial type. SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins].	3.64831e-16
NC_010511.1\|WP_012333640.1\|4318807_4319359_+\|cupin-domain-containing-protein	gnl\|CDD\|182158	PRK09943, PRK09943, HTH-type transcriptional regulator PuuR.	4.14332e-36
NC_010511.1\|WP_150108695.1\|4321233_4321446_-\|MerR-family-transcriptional-regulator	gnl\|CDD\|133393	cd04765, HTH_MlrA-like_sg2, Helix-Turn-Helix DNA binding domain of putative MlrA-like transcription regulators. Putative helix-turn-helix (HTH) MlrA-like transcription regulators (subgroup 2), N-terminal domain. The MlrA protein, also known as YehV, has been shown to control cell-cell aggregation by co-regulating the expression of curli and extracellular matrix production in Escherichia coli and Salmonella typhimurium. These proteins belong to the MerR superfamily of transcription regulators that promote expression of several stress regulon genes by reconfiguring the spacer between the -35 and -10 promoter elements. Their conserved N-terminal domains contain predicted HTH motifs that mediate DNA binding, while the dissimilar C-terminal domains bind specific coactivator molecules.	3.85519e-11
NC_010511.1\|WP_150108854.1\|4313768_4316273_-\|FAD-dependent-oxidoreductase	gnl\|CDD\|223481	COG0404, GcvT, Glycine cleavage system T protein (aminomethyltransferase) [Amino acid transport and metabolism].	1.14458e-129
NC_010511.1\|WP_012333635.1\|4312138_4312924_-\|ABC-transporter-permease	gnl\|CDD\|224098	COG1177, PotC, ABC-type spermidine/putrescine transport system, permease component II [Amino acid transport and metabolism].	1.48162e-63
NC_010511.1\|WP_012333650.1\|4325411_4326461_-\|tyrosine-type-recombinase/integrase	gnl\|CDD\|271181	cd00800, INT_Lambda_C, C-terminal catalytic domain of Lambda integrase, a tyrosine-based site-specific recombinase. Lambda-type integrases catalyze site-specific integration and excision of temperate bacteriophages and other mobile genetic elements to and from the bacterial host chromosome. They are tyrosine-based site-specific recombinase and belong to the superfamily of DNA breaking-rejoining enzymes, which share the same fold in their catalytic domain and the overall reaction mechanism. The phage lambda integrase can bridge two different and well-separated DNA sequences called arm- and core-sites. The C-terminal domain binds, cleaves and re-ligates DNA strands at the core-sites, while the N-terminal domain is largely responsible for high-affinity binding to the arm-type sites.	1.92211e-31
NC_010511.1\|WP_012333652.1\|4329342_4329942_+\|cysteine-hydrolase	gnl\|CDD\|238496	cd01014, nicotinamidase_related, Nicotinamidase_ related amidohydrolases. Cysteine hydrolases of unknown function that share the catalytic triad with other amidohydrolases, like nicotinamidase, which converts nicotinamide to nicotinic acid and ammonia.	8.3573e-62
NC_010511.1\|WP_043701402.1\|4323168_4323417_-\|DNA-binding-protein	gnl\|CDD\|378935	pfam12728, HTH_17, Helix-turn-helix domain. This domain is a DNA-binding helix-turn-helix domain.	0.00192044
NC_010511.1\|WP_043701396.1\|4320409_4320631_+\|DUF3606-domain-containing-protein	gnl\|CDD\|371985	pfam12244, DUF3606, Protein of unknown function (DUF3606). This family of proteins is found in bacteria. Proteins in this family are typically between 58 and 85 amino acids in length. There is a single completely conserved residue G that may be functionally important.	9.85897e-13
NC_010511.1\|WP_012333638.1\|4316662_4317268_+\|helix-turn-helix-domain-containing-protein	gnl\|CDD\|380339	cd02209, cupin_XRE_C, XRE (Xenobiotic Response Element) family transcriptional regulators, C-terminal cupin domain. This family contains transcriptional regulators containing an N-terminal XRE (Xenobiotic Response Element) family helix-turn-helix (HTH) DNA-binding domain and a C-terminal cupin domain. Included in this family is Escherichia coli transcription factor SutR (YdcN) that plays a regulatory role in sulfur utilization; it regulates a set of genes involved in the generation of sulfate and its reduction, the synthesis of cysteine, the synthesis of enzymes containing Fe-S as cofactors, and the modification of tRNA with use of sulfur-containing substrates. This family belongs to the cupin superfamily with a conserved "jelly roll-like" beta-barrel fold capable of homodimerization.	3.27562e-29
NC_010511.1\|WP_012333649.1\|4324121_4325264_+\|site-specific-integrase	gnl\|CDD\|271189	cd01189, INT_ICEBs1_C_like, C-terminal catalytic domain of integrases from bacterial phages and conjugate transposons. This family of tyrosine based site-specific integrases is has origins in bacterial phages and conjugate transposons. One member is the integrase from Bacillus subtilis conjugative transposon ICEBs1. ICEBs1 can be excised and transfered to various recipients in response to DNA damage or high concentrations of potential mating partners. The family belongs to the superfamily of DNA breaking-rejoining enzymes, which share the same fold in their catalytic domain and the overall reaction mechanism. The catalytic domain contains six conserved active site residues. Their overall reaction mechanism involves cleavage of a single strand of a DNA duplex by nucleophilic attack of a conserved tyrosine to give a 3' phosphotyrosyl protein-DNA adduct. In the second rejoining step, a terminal 5' hydroxyl attacks the covalent adduct to release the enzyme and generate duplex DNA.	3.5781e-32
NC_010511.1\|WP_012333636.1\|4312920_4313772_-\|ABC-transporter-permease	gnl\|CDD\|224097	COG1176, PotB, ABC-type spermidine/putrescine transport system, permease component I [Amino acid transport and metabolism].	9.16418e-67
NC_010511.1\|WP_012333639.1\|4317324_4318662_-\|aspartate-aminotransferase-family-protein	gnl\|CDD\|181707	PRK09221, PRK09221, beta alanine--pyruvate transaminase; Provisional.	0

>NC_010511.1|WP_150108696.1|4321417_4321816_-|hypothetical-protein
MFIHNSPCLEQAFLCAVVEYVAWEKWNDDIKHNGTRQADGSHRYQSEPSIMFEGEYVKISKICQYATGLLIGPVPEHVKQLFHNVVLLGQAIPPGEEVLTYPDAIDTLEQMIEAENERDDSDPLDGVFKDYW
>NC_010511.1|WP_150108695.1|4321233_4321446_-|MerR-family-transcriptional-regulator
MMVSLRTTGNPDLQPVARNERRYYQPDDMALLRGLQALLHRAGLTIEGAKRVMNKHWAGEVRTVGNGSTT
>NC_010511.1|WP_043701399.1|4320672_4321143_-|hypothetical-protein
MTDSPTSLDRDRLAKCIALAERGATAGERAAARAAAERVARSAGLRLDEAVKIVGGASPKPSPSHPSGPPRAQRTRPAPSKPVVEPITVEELLRQRAKYAEHLKRRATRQQREDARIIAEQEAYWAPIREEQARRDREWAEQKRRQQEAARPGPAS
>NC_010511.1|WP_043701396.1|4320409_4320631_+|DUF3606-domain-containing-protein
MRRRAIADANHSRPVGDPEVVLLDDPGTRAFWARRFQEPAKKIEQAVEDVGNDPARVAQYLGKPWPYEKSGIV
>NC_010511.1|WP_012333640.1|4318807_4319359_+|cupin-domain-containing-protein
MTNDEVGARLRYVRTLHGLSQRALARKAGIVNSTISLIESGQTNPSVGALKRILDAVPIGLAEFFSLEPARTEKAFYAAEDLVEIGKGRISYRQVGETLIGRALQILKERYEPGSDTGRVPLVHDGEEGGLVLSGRLEVTVDDERKVLGPGDAYYFASRRPHRFRCVGPLPCEVVSACTPPTF
>NC_010511.1|WP_012333639.1|4317324_4318662_-|aspartate-aminotransferase-family-protein
MTTPLRANRPRLDAYWMPFTANRQFKAAPRLLVAAEGMHYTADDGRTVLDGTAGLWCVNAGHGRRRIVEAVAHQLSTLDYAPSFQMGHPIAFDFAERLAAIAPGPDGSRLDRVFFTGSGSESVDTALKIALAYQRAVGQGTRTRLIGRERGYHGVGFGGISVGGLVSNRRMFPLLPGADHLRHTHDLARNAFVKGQPEHGAELADDLERMVALHGAETIAAVIVEPVAGSTGVLVPPKGYLERLRDIATRHGVLLIFDEVITGFGRLGAPFATDFFGVTPDLVTAAKGLTNGTVPMGAVFASRAVHDALMRGPQDAIELFHGYTYSGHPAGCAAGLATLDVYEEEGLLTRVAELQEFWHEAMHGLRAARNVIDVRTIGLIAGIELAPRAGAPGARAYDAFVDCFEKGLLIRVTGDIIALSPPLIAERRHVDDMVSMLADALGRAA
>NC_010511.1|WP_012333638.1|4316662_4317268_+|helix-turn-helix-domain-containing-protein
MPRDEVDAASPAAAGNEQELLLGEQIRALRKIKGLTLQQIAGEIGVSIGYLSQIERNRSKLPIGVLKRIATILGVQLSWFFQPQTLGPPEEQDFIVRAGRRRRMSFTGTGIAEELLSPNLNGPLEVLLSTIAPGSDSDFYSHDGMEAGLVLAGTLDLWIGDRTFRLEVGDSFSFSSRERHRCANPGEIETKVVWIITPPHY
>NC_010511.1|WP_150108854.1|4313768_4316273_-|FAD-dependent-oxidoreductase
MVIVGGGIVGCSVAYHLTLRGCTDVVLLERKQLTSGTTWHAAGLVGQLRATHNLTRLAQYTTELYATLEAQTGQATGFLQIGSLGLATNAERMEELRRGAAMARCFGLEVNVLTSDEARALWPLMAADDLVGAVHLPRDGQTNPIDTTQALAKGARMRGARIFENLAVDEIVVEGGRAVGVRTALGDIRAEAVVNCAGMWAHDLGARAGATVPLHAAEHFYVVTEPMPGLPPHLPVLRDADNCTYIKEDAGKLLVGWFEPVAKPWGMDGIPESFAFDSLPDDLEHIEPLLEAAVRRVPALGEAGIQLFFNGPESFTPDDRYLLGETAEVRGLFVAAGFNSIGIQSAGGAGKVLSDWIIDGHPPMDLWDVDIRRTLPFQRNRRYLRDRTVESLGLLYDMHWPFRQPTTARGVRRSTLHDRLAERGACFGEAAGWERPNWFAPEGEAAQYRYTFGRQNWFPHSAAEHRATREAVGLFDLSSFAKFVLDGADAEAALNRICANDIAIPVGQVVYTPWLNERGGIEADVTVTRESETRFLIVTAAATQARDFAWLTRNIPAEARATALDVTSAQAVLGIMGPRSRELLSLLTDADLSNAAFPFGTSRVVDLAYARVRASRITYVGELGWELFIPTEFAQGVFDALMAAGRDLGLRLAGYHALNSLRMEKGYRHWGHDITDEDTPLESGLSFAVAWDKNGGFIGREALLRRRDHVPSRRLVGIALESPDHLLYHNEPILRDGRIIGRVTSGMFGHTVGRALGLGYVATNGQALTADALAAHRIEVDVAGERVPARLSLEPFYDPEDRRIQDLPAETELGRGPAITPSMPLPRQLRSETP
>NC_010511.1|WP_012333636.1|4312920_4313772_-|ABC-transporter-permease
MRSAPHSLRARLVTAALLLPFVLFVALAFALPMLRLIELSLSSPEGAFASYIEIASSSVYRAVFANTVVLALSVAALTTLLAYPTAYMVSELRGWKRSLALWCVLFPLWISVLVRTFSWILLLERNGPVNRLLLASGLVDTPVSLLFNSAGVHIGMVQVLLPYALLPILTSMRTFDGRLLLASDALGARPITTFWRVYLPLTLPGVMAGFTLVFLLGLGFYITPAILGGPGNMTIAMLIDQFVTERLVWPLAAAASVWLLAVIVLLMAVASRFVGLVNVVAAR
>NC_010511.1|WP_012333635.1|4312138_4312924_-|ABC-transporter-permease
MSAARILVYAVGSATLAFLVSPLAAVVPASFSRASFIQIPPAIWSTRWYEAFWSDPEWFSSFETSIRVAVLASALSLGIGTLAALGLQQVSPRPRAAIMAVVLSPLIVPVIMISIALYAVARPLGLHGTVLGLALGHTLLALPFVVINVGLALSALDPNYARAAECLGAAPWRVFRTVTLPLIAPGLAGAAAFAFITSFDEVVLSIFLSGIEAKTLPVKMWEVIRVEFTPVSAVAATILIAITVVLFAAVQAIRGRSETEG
>NC_010511.1|WP_012333645.1|4322372_4322921_-|hypothetical-protein
MRRRKPAKADKTGRSTVQSDPQQGPAIWQGHWTSLGRDLLDSHAWRAQSINCRRVIDRILLEHIGHGGLTNGALAVTHADFGRHGIRGNSVLPAIEEAIALGLIRREREGHRAWGAFKGRAAMFGLTWFGTVDGRPPSNEWKRFGSREEAEQAAKNARQRVEESASSRPARRNRVNPVPNAA
>NC_010511.1|WP_012333646.1|4322917_4323172_-|hypothetical-protein
MSAIVLPFPRSRDRAFISRHASIMTAAATTAKAEAHLRRQLELQRQTMERRGINSATIDAELQDIQGHVRAVVWSLLLAPGGAA
>NC_010511.1|WP_043701402.1|4323168_4323417_-|DNA-binding-protein
MNAGTARHEGVNGGAMPDDVIIGAEGISVAIYGPEEGIRETNIRRIYHAIAKGDLPTFKLGGRVHARRSTILAWIEKQEGVS
>NC_010511.1|WP_012333648.1|4323429_4324002_-|hypothetical-protein
MALLSDLVRTVALVEGLDEVSVGIFARAARESGYLSQGGRGRSAAKMNERDAANLLIAVNGCALAKDVKENLPLFRDLRVSKAGAKNYTGVGERWSTLGDDLETLIKEMGIQNYLGVTDDYPGSISIRFERPILRAEIFLIFEEKWVEDRFVHVEYGSVDHDKLDSYGDRLDQTIISHKTLIAVARALAS
>NC_010511.1|WP_012333649.1|4324121_4325264_+|site-specific-integrase
MATIRKRELPSGKIAWLASYTDGGGKRRFRQFATRKEADAFLTRARSEVAHGVHIPDSQSMTVGQAADAWLKHAEEGGLEWSTVLHYQQHVNEHIRPLIGSLRLTQVTTPRVYSFAEELRAKGRSPEMVRRAVQSLGRIFRFAKGRGLAGQNPVADVKLKRSKRDQARVEIPTREELRAILGAAQGRWRPLIVTAMFTALRASELRGLRWSDVDLKRRVLTVRQRADAWKRIGPPKSEAGTRDVPLAPMVVNTLREWRLACPKGELDLVFPSGAGQVEHHPNIIARGWEPTQIAAGVVEMVDGKDKAGNPAKAAKGRYNFHALRHAAASMFIESGMTPKRVQAIMGHSSIIVTYDTYGHLFSDDEADQNAMRTIEERLLG
>NC_010511.1|WP_012333650.1|4325411_4326461_-|tyrosine-type-recombinase/integrase
MRVRLKGINSRRKRLADGTWRTYWYAWKGGPRLEGEPGTPEFMASYNTAVARRVETKQGVLLSLIQGFQASDSFLGKEPRTRADYVRHIKVIEQEFGDFPLGALTDRRTRGEFLTWRDRLAVRSRRQADYAWSVLARILSWALDRGLILANPCERGGRLYRASRTDKVWTDDDERRFLASAPAHLHLPLILALWTGQRQGDLLRLPWSAYDGETVRLKQGKTGARVVIPVGAPLRAALDAAPRVSPVILVNSEGRPWTGDGFRSSWGKACRAAGIRGLTFHDLRGTAVSRLALAGCSEAEIATLTGHSLRDVRSILDAHYLNRDPALALAAVRKLETRMNSPDRTPDRA
>NC_010511.1|WP_012333651.1|4326444_4326639_-|hypothetical-protein
MPRRRTITKAQIARAVSGAQAGGLKVDRVEIADGTIVIHSGEPAKAETATEFDAWRAKRDARPA
>NC_010511.1|WP_150108697.1|4326650_4327229_-|hypothetical-protein
MVTTSYLDIPQLLLSDAADVVGMEFNTLRSWIQRGAVYLSKFDQKPKSKGGRTIITLRSMYCYAIMNELVKFGFSPDKAGIVATEAVRYTLFVSVAHNPEDLVDLEPGQLFPEGKTFLVTFGHETFQDPEEGVVNSAAVNLVNVRTGDQYAQLFEGSETFSSKSTRLIINLNILYNRVNERLADLRSNRRGS
>NC_010511.1|WP_012333652.1|4329342_4329942_+|cysteine-hydrolase
MSDLATLRGLSGLSPEPASLKRSALLLIDLQETYRNGVMRLEGAEPAIREAAALLARARDTGIPVFHVRHDAGPGSPYDVSAPIGQISPEVAPQGDEAVITKTYPSSFVGTDLEKRLRAANVQDVIVAGFMTHMCVNSTVRSAFSLGFRPTVVASATATRDLPAPDGSVVPASQLQVASLAALADLFAVVAPKQTDIPD
>NC_010511.1|WP_012333653.1|4330446_4331619_+|hypothetical-protein
MAIDVRSDLRRPTTLALAALSVLLLVILLVSSISHSRQRQAQEQQIGNLNSQLAAVQSELQQQTRAAGTLKELQAKIAATEQQNTQTAQAAQQAQAQLRELEQSRQVAEQKARDALQAAQAPTQRLAELQSDVQKAGQQVATLREAAISAEQTAAARTQELSDVGRRVEEARKQEAKLRTDLAALAQEATAKTAELADAEQRQQQAREGLAAAQKELLQVRADRERVAQQRGELDQTITSLTQARDKTSADKSQIEQQLQQTRDSLMSAQKDVAAAQAERDRLTGERGQVEQAIKALTGNREKLTSDLESVQKRYAEAQAQLATLTENLAAKNKEVADLEGRLRTTRQELAEAQGKLADARQQLSGQPAADGSAPAATGSTSPEGETKPQ

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Crispr_ID: NC_010511_27

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_010511_27

4397341-4397435

Orphan

Consensus_repeat	Method
AGCCCGCGCGGCGCTTGAGCGAAGCC	CRISPRCasFinder

1 spacers

The CRISPR arrays of NC_010511_27

>merge|NC_010511|27|4397341-4397435|CRISPRCasFinder
AGCCCGCGCGGCGCTTGAGCGAAGCCCCAATCCGCCATCCCGAAGGGATCAAGCGGATTTGGTATGACGAGCCCGCGCGGCGCTTGAGCGACGCC

>NC_010511|27|27|4397341-4397435|CRISPRCasFinder
AGCCCGCGCGGCGCTTGAGCGAAGCC	CCAATCCGCCATCCCGAAGGGATCAAGCGGATTTGGTATGACG
AGCCCGCGCGGCGCTTGAGCGACGCC

Protein	Signature genes	Signature genes Name	Protein_function
NC_010511.1\|WP_012333713.1\|4399246_4400299_+\|UPF0104-family-protein	unknown	unknown	gnl\|CDD\|223469
NC_010511.1\|WP_012333705.1\|4390827_4391559_+\|ATP-binding-cassette-domain-containing-protein	unknown	unknown	gnl\|CDD\|213227
NC_010511.1\|WP_012333707.1\|4392417_4394061_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|276808
NC_010511.1\|WP_012333714.1\|4400305_4401157_+\|class-I-SAM-dependent-methyltransferase	unknown	unknown	gnl\|CDD\|379276
NC_010511.1\|WP_012333711.1\|4397488_4398070_-\|GNAT-family-N-acetyltransferase	unknown	unknown	gnl\|CDD\|366181
NC_010511.1\|WP_012333702.1\|4388374_4389421_+\|MaoC-family-dehydratase	unknown	unknown	gnl\|CDD\|239535
NC_010511.1\|WP_012333712.1\|4398229_4399117_+\|alpha/beta-fold-hydrolase	unknown	unknown	gnl\|CDD\|366166
NC_010511.1\|WP_012333719.1\|4407708_4408098_+\|hypothetical-protein	unknown	unknown	unknown
NC_010511.1\|WP_012333720.1\|4408143_4408968_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|377730
NC_010511.1\|WP_012333716.1\|4402431_4403868_-\|CoA-transferase	unknown	unknown	gnl\|CDD\|367110
NC_010511.1\|WP_012333701.1\|4387983_4388298_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|167208
NC_010511.1\|WP_012333718.1\|4405244_4407371_-\|flagellar-biosynthesis-protein-FlhA	unknown	unknown	gnl\|CDD\|235672
NC_010511.1\|WP_012333717.1\|4403928_4405089_+\|citrate-synthase	unknown	unknown	gnl\|CDD\|99856
NC_010511.1\|WP_012333708.1\|4394121_4394823_-\|response-regulator-transcription-factor	unknown	unknown	gnl\|CDD\|223816
NC_010511.1\|WP_012333710.1\|4396807_4397215_+\|flagellar-export-protein-FliJ	unknown	unknown	gnl\|CDD\|131526
NC_010511.1\|WP_012333704.1\|4390135_4390831_+\|ABC-transporter-permease	unknown	unknown	gnl\|CDD\|227008
NC_010511.1\|WP_012333709.1\|4395325_4396681_+\|flagellar-protein-export-ATPase-FliI	unknown	unknown	gnl\|CDD\|236351
NC_010511.1\|WP_012333706.1\|4391528_4392344_+\|solute-binding-protein	unknown	unknown	gnl\|CDD\|225544
NC_010511.1\|WP_012333703.1\|4389433_4389925_-\|manganese-binding-transcriptional-regulator-MntR	unknown	unknown	gnl\|CDD\|182927
NC_010511.1\|WP_012333715.1\|4401397_4402342_-\|cation-transporter	unknown	unknown	gnl\|CDD\|224151

Protein	Function_ID	Function_description	E-value
NC_010511.1\|WP_012333713.1\|4399246_4400299_+\|UPF0104-family-protein	gnl\|CDD\|223469	COG0392, COG0392, Predicted integral membrane protein [Function unknown].	3.36664e-39
NC_010511.1\|WP_012333705.1\|4390827_4391559_+\|ATP-binding-cassette-domain-containing-protein	gnl\|CDD\|213227	cd03260, ABC_PstB_phosphate_transporter, ATP-binding cassette domain of the phosphate transport system. Phosphate uptake is of fundamental importance in the cell physiology of bacteria because phosphate is required as a nutrient. The Pst system of E. coli comprises four distinct subunits encoded by the pstS, pstA, pstB, and pstC genes. The PstS protein is a phosphate-binding protein located in the periplasmic space. PstA and PstC are hydrophobic and they form the transmembrane portion of the Pst system. PstB is the catalytic subunit, which couples the energy of ATP hydrolysis to the import of phosphate across cellular membranes through the Pst system, often referred as ABC-protein. PstB belongs to one of the largest superfamilies of proteins characterized by a highly conserved adenosine triphosphate (ATP) binding cassette (ABC), which is also a nucleotide binding domain (NBD).	7.75387e-67
NC_010511.1\|WP_012333707.1\|4392417_4394061_+\|hypothetical-protein	gnl\|CDD\|276808	sd00008, TPR_YbbN, C-terminal Tetratricopeptide repeat (TPR) region of YbbN and similar motifs. The Tetratricopeptide repeat (TPR) typically contains 34 amino acids and is found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi, plants, and humans. It is present in a variety of proteins including those involved in chaperone, cell-cycle, transcription, and protein transport complexes. YbbN is a thioredoxin-like protein containing two tandem TPR repeats at the C-terminus, separated by two alpha helices. Its N-terminal thioredoxin-like domain is not a functional oxidoreductase. It functions in heat stress response and DNA synthesis as a chaperone or co-chaperone.	0.00256671
NC_010511.1\|WP_012333714.1\|4400305_4401157_+\|class-I-SAM-dependent-methyltransferase	gnl\|CDD\|379276	pfam13578, Methyltransf_24, Methyltransferase domain. This family appears to be a methyltransferase domain.	1.44362e-16
NC_010511.1\|WP_012333711.1\|4397488_4398070_-\|GNAT-family-N-acetyltransferase	gnl\|CDD\|366181	pfam00583, Acetyltransf_1, Acetyltransferase (GNAT) family. This family contains proteins with N-acetyltransferase functions such as Elp3-related proteins.	3.78813e-09
NC_010511.1\|WP_012333702.1\|4388374_4389421_+\|MaoC-family-dehydratase	gnl\|CDD\|239535	cd03451, FkbR2, FkbR2 is a Streptomyces hygroscopicus protein with a hot dog fold that belongs to a conserved family of proteins found in prokaryotes and archaea but not in eukaryotes. FkbR2 has sequence similarity to (R)-specific enoyl-CoA hydratase, the peroxisomal Hydratase-Dehydrogenase-Epimerase (HDE) protein, and the fatty acid synthase beta subunit. The function of FkbR2 is unknown.	1.59096e-54
NC_010511.1\|WP_012333712.1\|4398229_4399117_+\|alpha/beta-fold-hydrolase	gnl\|CDD\|366166	pfam00561, Abhydrolase_1, alpha/beta hydrolase fold. This catalytic domain is found in a very wide range of enzymes.	8.20524e-20
NC_010511.1\|WP_012333720.1\|4408143_4408968_+\|hypothetical-protein	gnl\|CDD\|377730	pfam06897, DUF1269, Protein of unknown function (DUF1269). This family consists of several bacterial and archaeal proteins of around 200 residues in length. The function of this family is unknown. The family carries a repeated glycine-zipper sequence- motif, GxxxGxxxG, where the x following the G is frequently found to be an alanine. As glycine-zippers occur in membrane proteins, this family is likely to be found spanning a membrane.	5.57449e-05
NC_010511.1\|WP_012333716.1\|4402431_4403868_-\|CoA-transferase	gnl\|CDD\|367110	pfam02515, CoA_transf_3, CoA-transferase family III. CoA-transferases are found in organisms from all lines of descent. Most of these enzymes belong to two well-known enzyme families, but recent work on unusual biochemical pathways of anaerobic bacteria has revealed the existence of a third family of CoA-transferases. The members of this enzyme family differ in sequence and reaction mechanism from CoA-transferases of the other families. Currently known enzymes of the new family are a formyl-CoA: oxalate CoA-transferase, a succinyl-CoA: (R)-benzylsuccinate CoA-transferase, an (E)-cinnamoyl-CoA: (R)-phenyllactate CoA-transferase, and a butyrobetainyl-CoA: (R)-carnitine CoA-transferase. In addition, a large number of proteins of unknown or differently annotated function from Bacteria, Archaea and Eukarya apparently belong to this enzyme family. Properties and reaction mechanisms of the CoA-transferases of family III are described and compared to those of the previously known CoA-transferases.	4.55665e-42
NC_010511.1\|WP_012333701.1\|4387983_4388298_+\|hypothetical-protein	gnl\|CDD\|167208	PRK01310, PRK01310, hypothetical protein; Validated.	3.17966e-31
NC_010511.1\|WP_012333718.1\|4405244_4407371_-\|flagellar-biosynthesis-protein-FlhA	gnl\|CDD\|235672	PRK06012, flhA, flagellar type III secretion system protein FlhA.	0
NC_010511.1\|WP_012333717.1\|4403928_4405089_+\|citrate-synthase	gnl\|CDD\|99856	cd06102, citrate_synt_like_2, Citrate synthase (CS) catalyzes the condensation of acetyl coenzyme A (AcCoA) and oxalacetate (OAA) to form citrate and coenzyme A (CoA), the first step in the oxidative citric acid cycle (TCA or Krebs cycle). Peroxisomal CS is involved in the glyoxylate cycle. This group also includes CS proteins which functions as a 2-methylcitrate synthase (2MCS). 2MCS catalyzes the condensation of propionyl-CoA (PrCoA) and OAA to form 2-methylcitrate and CoA during propionate metabolism. This group contains proteins which functions exclusively as either a CS or a 2MCS, as well as those with relaxed specificity which have dual functions as both a CS and a 2MCS. The overall CS reaction is thought to proceed through three partial reactions and involves both closed and open conformational forms of the enzyme: a) the carbanion or equivalent is generated from AcCoA by base abstraction of a proton, b) the nucleophilic attack of this carbanion on OAA to generate citryl-CoA, and c) the hydrolysis of citryl-CoA to produce citrate and CoA. There are two types of CSs: type I CS and type II CSs. Type I CSs are found in eukarya, gram-positive bacteria, archaea, and in some gram-negative bacteria and are homodimers with both subunits participating in the active site. Type II CSs are unique to gram-negative bacteria and are homohexamers of identical subunits (approximated as a trimer of dimers). Some type II CSs are strongly and specifically inhibited by NADH through an allosteric mechanism. This subgroup includes both gram-positive and gram-negative bacteria.	1.19812e-95
NC_010511.1\|WP_012333708.1\|4394121_4394823_-\|response-regulator-transcription-factor	gnl\|CDD\|223816	COG0745, OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription].	3.35149e-75
NC_010511.1\|WP_012333710.1\|4396807_4397215_+\|flagellar-export-protein-FliJ	gnl\|CDD\|131526	TIGR02473, conserved_hypothetical_protein, flagellar export protein FliJ. Members of this family are the FliJ protein found, in nearly every case, in the midst of other flagellar biosynthesis genes in bacgterial genomes. Typically the fliJ gene is found adjacent to the gene for the flagellum-specific ATPase FliI. Sequence scoring in the gray zone between trusted and noise cutoffs include both probable FliJ proteins and components of bacterial type III secretion systems.	2.77384e-11
NC_010511.1\|WP_012333704.1\|4390135_4390831_+\|ABC-transporter-permease	gnl\|CDD\|227008	COG4662, TupA, ABC-type tungstate transport system, periplasmic component [Coenzyme metabolism].	3.48598e-53
NC_010511.1\|WP_012333709.1\|4395325_4396681_+\|flagellar-protein-export-ATPase-FliI	gnl\|CDD\|236351	PRK08927, fliI, flagellar protein export ATPase FliI.	0
NC_010511.1\|WP_012333706.1\|4391528_4392344_+\|solute-binding-protein	gnl\|CDD\|225544	COG2998, TupA, tungsten ABC transporter substrate-binding protein [Coenzyme metabolism].	3.26705e-110
NC_010511.1\|WP_012333703.1\|4389433_4389925_-\|manganese-binding-transcriptional-regulator-MntR	gnl\|CDD\|182927	PRK11050, PRK11050, manganese-binding transcriptional regulator MntR.	2.96605e-79
NC_010511.1\|WP_012333715.1\|4401397_4402342_-\|cation-transporter	gnl\|CDD\|224151	COG1230, CzcD, Co/Zn/Cd efflux system component [Inorganic ion transport and metabolism].	1.87795e-97

>NC_010511.1|WP_012333710.1|4396807_4397215_+|flagellar-export-protein-FliJ
MKSRDTLIRLRRFQVDEKRRRVTQIESMIADFARMAAELDREVAQEEQRAGITDPAHFAYPTYARAAAQRRDNIRRSASDLDAQLAEAKAALAEAFEELKKVEILDDRERSAERAADAAREQSDLDAIGLGRARA
>NC_010511.1|WP_012333709.1|4395325_4396681_+|flagellar-protein-export-ATPase-FliI
MGQEGGGAGRLAAARAALDGVETLEVFGRVVAIRGLLVEVAGPVAAMRLGGRLDIAVEGRGGEGSVPCEIIGFSGSHALAMPFGSLQGVRRGCPARVGAEEAGAIRPSPAWLGRVVDALGRPVDGRGPLPPGPLPYPLRADPPPAHARARVGPPLDLGVRCINTFLTMCVGQRMGIFAGSGVGKSVLLSMLARAAACDVAVIGLVGERGREVQEFLQDDLGPEGLARSVVVVATSDEPALMRRNAAYVTLALAESFRDAGAQVLCMIDSVTRFAMAQRDVGLAAGEPPTAKGYTPTVFSELPRLLERAGPGTGAGSISGLFTVLVEGDDHNEPVADAVRGILDGHIVMERRIAEGGRYPAINVLRSVSRTMPRACDPAFLPTVQRARWLLSTYADMEELIRLGAYRPGSSPDVDEAIGLMPDLEAFMRQGKEEATSLGEGYQRLAAIVGGP
>NC_010511.1|WP_012333708.1|4394121_4394823_-|response-regulator-transcription-factor
MRVLLIEDDSATAQSIELMLKSENFNTYTTDLGEEGVDLGKLYDYDIILLDLNLPDMSGYEVLRSLRVAKVKTPILILSGMAGIEDKVKGLGFGADDYLTKPFHKDELVARIHAIVRRSKGHAQSVITTGDLIVNLDQKTVEVSGARVHLTGKEYQMLELLSLRKGTTLTKEMFLNHLYGGMDEPELKIIDVFICKLRKKLANASQGKNYIETVWGRGYVLREPTDDEDRIAV
>NC_010511.1|WP_012333707.1|4392417_4394061_+|hypothetical-protein
MPASSLWRRARALLGPRGAGEEAFDPDFYARRYLDARALSPEERARHFAVTGRREGRAPNAEVFLHRLAAHYGPPEPDFDLAFYRRQPDLAEVFAQDWEFLAHYLERGRGEGRPRNVADHLARLERAHGPLGPHFEIDAYRRNEDLALLFDDEWQFVAHFLQWGRAEGRFFRHAQFALCDAAREARVAGRFEEAIGHARALVAALPRNREAASLLVHLLTVTGREREAQAALAEAGLAPAEGAALRALGAYLRRVPREQALALVDGLPGRFTYLEPGGVAERILAAKAARRPFALLRLGDGEGCLLRVDAADEAAFAPLYAANRETFARIWFGDRFDAAGSGFSTLAAGLSEAAAEADILGVPYRAWIEHEYRIVTPSGVPGVTNVLRWLDARAAAGLPVPPLCQQTIHVALGQGDFFRDLLAGEAEVGLIACFPDLPEAIRRRFGVGAVEFHKIPGEQMSRRLIGEQAAGGAHYPDVFEAVTARLSRPLDGRIFLVAGGLLGKFYALTIRRHGGIAIDIGSLADVWMQKVTRPGYEHLAGLALTET
>NC_010511.1|WP_012333706.1|4391528_4392344_+|solute-binding-protein
MDRLRRLFCLTLAAWLAAAPARAGESITVASTTSTEQSGLFGHLLPRFTEATGIGVRVVALGTGQALDVGRRGDADVVFVHDQPAEEAFVRDGFGVERFPVMYNDFVVIGPRDDPAGIAGRDVAQAFRKIAAARAPFVSRGDRSGTHAAELRMWREAGLDLGAVRGEWYKEIGQGMGPALNAAAATNAYLLADRGTWLAFKNRQDLKVLVEGDPRLFNQYGVILVNPAKHPHVKARAGQAFIDWLVSPAGQGVIAGYRIGGEPLFVPNAGT
>NC_010511.1|WP_012333705.1|4390827_4391559_+|ATP-binding-cassette-domain-containing-protein
MSPALPILLDGLSFRAGGRTILDRVSLRIEEPGITALIGPNGAGKSVLLRLLDGLLPLSAGAVRIGPGGAPARRAFVFQRPGLVRASAGHNIRLALAAAGWRRAEARARCRAALALVGLADRARDPATRLSGGEQQRLALARAWAVAPDLLLLDEPTANLDPAAAERVEQVVAGMAREGVKVLLVSHHLGQVARLARDVVVLSGGRVAEHGPVSQVLTHPRAPETRAYLAGELPWTAFAACSA
>NC_010511.1|WP_012333704.1|4390135_4390831_+|ABC-transporter-permease
MGETVRETLAKLAGLDREVVAIAWLSLRVSLSAVLIGAGLGIPLGALAAVARFPGRDALVSLLNALMGLPPVIIGLLLYLLLSRSGPLGPLGLLFTPAAMIAAQTVLVTPLVAALARQILADAEAQLGEQLRSLGLGPLRRAAALVHDARFSLVTVVLAAFGRAISEVGAVLVVGGNIAGQTRTMTTAISLETQKGDLPLALALGLVLIGLVVALNAAAALLRGYAARAYG
>NC_010511.1|WP_012333703.1|4389433_4389925_-|manganese-binding-transcriptional-regulator-MntR
MQHLPHDDAADSPPARDPQDETGLVDAERHSAGFRQVREARRLELVEDYVELIADLIGDTGEARQVDIAARLGVAQPTVAKMLKRLAEDGLVQQRPYRGVFLTEAGRALATESRERHRVVEAFLLALGVSPDVARCDAEGIEHHVSRETLDAFRRFTAGSGDA
>NC_010511.1|WP_012333702.1|4388374_4389421_+|MaoC-family-dehydratase
MKTNPGRFFEDFRLGETIRHATPRTVTTGDVALYTALYGPRFAVQSSDAFARAFGYERAPLDDLLVFHVVFGKTVPDISLNALANLGYAEGRFLRPVYPGETLSSVSEVIGLKESSNRQTGVVYVRSTGYDAGGAPVLTYCRWVLVRKRDPAAAIAEEAVPTLAKAVEAADLAASLPPFDPAAYDTVLAGSPHRFGDYAPGERIDHVDGMTVEEAEHQIATRLYQNTAKVHFDAHAVKETRFGRRLIYGGHVISLARALSFNGLANAFSIVGINAGRHVAPLFAGDTVYAWSEVLAAADLPGRSDVGALRLRTVAAKNQPCGAHPDRAGDGYDPAVILDLDYWALMPK
>NC_010511.1|WP_012333701.1|4387983_4388298_+|hypothetical-protein
MTRPWRLLTDGLEVRVRATPRGGRDAVEGIETRADGLPVLKVRVRAAPEDGAANAAIRAVLAEALGCPARAVTLAAGATARVKLFRVAGDGQALAARIGALLGP
>NC_010511.1|WP_012333711.1|4397488_4398070_-|GNAT-family-N-acetyltransferase
MNCDGLTPIPATHVAAVVTSLEMRNRPPLPDAPELPLAALGADLPRYRALFARIGTPWLWFSRRRMADAALAAILTDPAVEALALTRDGHDIGLVELDARVEGEVEIAFLGLVPEAVGRGIGRQLMGEALRRAWARPVSRVWVHTCTFDHPSAIGFYQASGFTPFARAIEVVPDPRLSGHLPREAAPHVPVLA
>NC_010511.1|WP_012333712.1|4398229_4399117_+|alpha/beta-fold-hydrolase
MTQDNGTGVHRFPVAAGPEGPTVSDMMARPDGPALEWVEARPLGQPRGAPLLFVHGAFGGAWIWQEIFLPHLARRGRRALAFSLRGHGRSQGARQLKEASLADYLYDLRAAIARCGEPPILVGHSLGALLAQRLIGQVPLRGLVLLAPLPPDGLALVGARIALTDPGFWVEALAGALLPGRGPAVALSRHWLFSEGLSFERARAYAARMSAESPVALAEAHWPAPTVPAALMGLPALVVGGARDRMIWPVTTWRTALYHGAQHRTVPDIAHFLQLDYGAEGVARLLIDWADERGL
>NC_010511.1|WP_012333713.1|4399246_4400299_+|UPF0104-family-protein
MKKIREFIWPAIGLAAVVVSIYLLWHQLKGLSIADVEASLKAIPPHRYALAAASTLMAYMALAWYDRIALIHLGVKGISWLFVSLCSFTTYALSHNIGASVFSGALVRYRAYTSKGLTAAQVAVLVALCSFTFGLGTMLLGGLVLTLQPDLLTRLTGMLPGVMTNPATARILGAGLLGVVGLYVVGSILHLKPLTIRSFKLEYPRPNVMVRQLIAAPLELIGAAGIIYFALPEAGNPGFLVVLAVFLASFSAALVSHAPGGLGVFELVFITAMPDLPKVEVLAAVLIFRLFYLLLPFAMAIVVVLLFERGRLAAAIRGKAELSPGAPAAPVDGPGLKPDLPASPPIRKVG
>NC_010511.1|WP_012333714.1|4400305_4401157_+|class-I-SAM-dependent-methyltransferase
MGRARLRRARLGLAALLGLPGGGYFIPYRHAAARAAQEGYPALEPLFREAEPDFRAHLAEIAARAGDLRRVAEGGPGLLGPRPPRLTQDWFPRLDAAAAYAMVRRARPRRIVEVGSGHSTRFLAQAVADGGMPTALTCIDPRPRAPLPALPGLRHEARLFGPRDGEALASLAPGDLLFIDSSHVAMPGSDVDRLLLDALPRLAPGVLVHLHDVFLPDAYPPEWAWRGYNEQVVVGALIQGGAFALAFASRYVATRTDWLAGSPLAGLPLPPGAFETSLWLRKR
>NC_010511.1|WP_012333715.1|4401397_4402342_-|cation-transporter
MGHDHAHHHHDHGHHHGHGHVHAPAEFGRAFAIGVALNTGFVLVEAVFGVLSDSVALLADAGHNLSDVLGLLIAWAAAVLARRAPSARFTYGLRGSSILAALFNAVFLLVAVGAIAWEAILRFADPPPVAGGTVITVALIGIAINGFTAWLFASGRKGDLNIRGAYLHMVADAAVSAGVVLAGLAIVLTGWTWIDPLVSLVIVAVIVAGTWGLLRDSVTMSLAAVPPGIDPVAVRRCLAERPGVAEVHDLHVWSMSTTETALTAHLVMPAGHPGNHFLAECGQVLRERFGIAHATLQVEIAGGPACALAPDHVV
>NC_010511.1|WP_012333716.1|4402431_4403868_-|CoA-transferase
MSERMRGAPPAGDDGRSGEAPILARILPAIGLAESRAGPLRFEGTALLPSAFPVAALAAAAIGTAALAVAELAATATAPAIRVSRPLSALWFARSLLPIGWTLPPAWDPVAGDYASRDGWIRLHTNAPRHRAAALSVLGCGADRPSVAAAASRWEAAALEEAVVAAGGCAAAMRSAAEWARHPQGCAVAAEPLVAFAPAETSPSAWRPSPGRPLAGLRILDLTRILAGPVATRFLAGFGADVLRIDPPDWEEDAVAPEVTLGKSCARLDLRAPRDRETFERLLAGADVLVHGYRPGALDALGYGEAARRSLRPGLIDVSLDAYGWSGPWRARRGFDSLVQMSSGIAEAGMRWRGAGVPVPLPVQALDHATGYLAAAAVLRALRHRLTDGRGLSARLSLARTAALLAAVQGEAAPPGSEGATQTDVATDFAEAAVEATGWGPARRASPPVSIAGTPVRWDRPARPLGSRPASWAESPPA
>NC_010511.1|WP_012333717.1|4403928_4405089_+|citrate-synthase
MIDTINMREWIDRDAALHALGIKPQTLYAYVSRGRIGMCPDPGDPRRSLYRADDVAALRARHIRGRKLADIAAGALAWGEPSLATSISTVHQGTLLYRGVGAVDWARAATLEDTAALLWQGDREIRFPAPRVRPREPFAALAALAASGRATLGLGGNGLRGDAATAIGHLAASLGAARGDAPVHRRLAEAWSLGESEGERIRLALILLAEHELNASTFAVRVAASTGASVAAGLLAGLCALSGPRHGGAGMALAALMGDARRCGAGEAVAAWLARGRALPGFGHPLYPAGDPRARALLAELAPDETARALQEAAFAETGDLPNVDFALACLAEALRLPGDAPLSLFLLGRSVGWSAHFIEQSAEGGLIRPRARYRGPGPRSGPAGP
>NC_010511.1|WP_012333718.1|4405244_4407371_-|flagellar-biosynthesis-protein-FlhA
MSDAKATGLDALRAFALPTRADLVGLTRRSDLVLAIAVMGILVVLIFPLPALLLDLLLAVSIILSVLILMTGLFIENPLEFTVFPTVLLIATMLRLALNLASTRLILGHGHEGTAAAGQVIEAFGHFVMGGNFLIGIIVFAILIIVNFVVITKGSGRIAEVAARFSLDAMPGKQMAIDADLSAGLIDEKTARARRQALEEESAFFGAMDGASKFVRGDAVAALLITFINVVGGIIIGTMQQGMGFGAAAQSYTLLTVGDGLVSQVPALIVSTAAGLLVSKAGVRGAADRALGRQIANYPKALGMSAAVMLLIALLPGIPMLPFLFLAGGAAYLARRIARMPKPVDPEAPAAGGAPGAGAAQPKEETVADLLRLDDLKLEMGYALLALVNGPGGQDRLTEQIKALRRQLAAELGFVMPSVRILDNVQLDANTYIVRVKEIEAGTGQVFPGQFMAMDPMGGQVQLPGQHLLEPTFGLPATWIDASLRDQAQLRGYTVVDAATVVSTHLTEVIKAHVSELLNHVEVQKLLRELPKEHTELLKEIVPSQIATTGIQRVLQYLLAERVSIRDLGTIVEGIAEVAGHVKNPRDIVEHVRARLGRQICAQYQGPGGVLPIITLSPAWESAFLDAIVGQGDERHLAMQPSRLSEFVTTVRDRFEEAARMGEMPVLVTSVQARPFVRSIIERFRRETPVMSQAEIHPRARLKTVGSV
>NC_010511.1|WP_012333719.1|4407708_4408098_+|hypothetical-protein
MRTTLITVATLSLLGAGIAQAQTTVTGEPARDAKPSTQSQGQEAVTRPNTDTVDKGNPGTTGTLTNAKLEPGANSFTEGQARSRLEKSGFTEIKDLKKDDQGIWRGHAMQSGKSVQVGLDFKGNVAANP
>NC_010511.1|WP_012333720.1|4408143_4408968_+|hypothetical-protein
MATRTISALFDSYDDAAAAVRKVEAAGVPHSDVSIVANNEGDRYSGHATAHDTAHKTSDGAGAGASVGTVLGGGAGLLAGLGLLAIPGVGPVVAAGWLVATLTGAGVGAAAGGLLGSLTGAGLSEDEAHAYAEGVRRGGTLVTVRADDATADRVTSLLKEHGSVDMDQRMQGWRSEGWTGRHDATGSYSNPATVAGGEVGSTAIGAAGSTTTGLGTGAPLPTSGVPYGAGPTPAGQAMDAAVERDTLAGTTRERHAAIEDELPPVRRPVETDRR

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Crispr_ID: NC_010511_28

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_010511_28

4448429-4448515

Orphan

Consensus_repeat	Method
AGCCCGCGCGGCGCCTGAGCGAAGCC	CRISPRCasFinder

1 spacers

The CRISPR arrays of NC_010511_28

>merge|NC_010511|28|4448429-4448515|CRISPRCasFinder
AGCCCGCGCGGCGCCTGAGCGAAGCCCCAATCCGCATTGCGACGCAATCCGTCGGATCACGAGCCCGCGCGGCGCTTGAGCGAAGCC

>NC_010511|28|28|4448429-4448515|CRISPRCasFinder
AGCCCGCGCGGCGCCTGAGCGAAGCC	CCAATCCGCATTGCGACGCAATCCGTCGGATCACG
AGCCCGCGCGGCGCTTGAGCGAAGCC

Protein	Signature genes	Signature genes Name	Protein_function
NC_010511.1\|WP_012333743.1\|4433375_4433567_-\|helix-turn-helix-domain-containing-protein	unknown	unknown	gnl\|CDD\|378935
NC_010511.1\|WP_012333749.1\|4444155_4445721_+\|hypothetical-protein	unknown	unknown	unknown
NC_010511.1\|WP_012333747.1\|4440412_4442020_-\|glycosyltransferase	unknown	unknown	gnl\|CDD\|274425
NC_010511.1\|WP_012333752.1\|4448727_4449327_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|380018
NC_010511.1\|WP_012333756.1\|4453189_4453681_+\|hypothetical-protein	unknown	unknown	unknown
NC_010511.1\|WP_150108856.1\|4434163_4435327_-\|integrase-arm-type-DNA-binding-domain-containing-protein	unknown	unknown	gnl\|CDD\|271182
NC_010511.1\|WP_012333758.1\|4454237_4455170_+\|glycosyltransferase-family-2-protein	unknown	unknown	gnl\|CDD\|366154
NC_010511.1\|WP_150108704.1\|4457810_4458038_-\|transposase-domain-containing-protein	unknown	unknown	gnl\|CDD\|379385
NC_010511.1\|WP_012333755.1\|4452679_4453132_+\|hypothetical-protein	unknown	unknown	unknown
NC_010511.1\|WP_012333760.1\|4457563_4457794_+\|hypothetical-protein	unknown	unknown	unknown
NC_010511.1\|WP_012333750.1\|4445717_4446893_+\|glycosyltransferase	unknown	unknown	gnl\|CDD\|340831
NC_010511.1\|WP_012333757.1\|4453730_4454234_+\|hypothetical-protein	unknown	unknown	unknown
NC_010511.1\|WP_150108702.1\|4433571_4433901_+\|hypothetical-protein	unknown	unknown	unknown
NC_010511.1\|WP_012333759.1\|4455166_4457167_+\|glycosyltransferase	unknown	unknown	gnl\|CDD\|340831
NC_010511.1\|WP_012333748.1\|4442557_4444117_+\|glycosyltransferase	unknown	unknown	gnl\|CDD\|340831
NC_010511.1\|WP_012333762.1\|4458121_4458769_-\|hypothetical-protein	unknown	unknown	unknown
NC_010511.1\|WP_012333751.1\|4446855_4448226_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|226689
NC_010511.1\|WP_012333753.1\|4450311_4451289_+\|glycosyltransferase	unknown	unknown	gnl\|CDD\|223515
NC_010511.1\|WP_150108858.1\|4438560_4440111_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|133018
NC_010511.1\|WP_150108857.1\|4436673_4438431_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|276809

Protein	Function_ID	Function_description	E-value
NC_010511.1\|WP_012333743.1\|4433375_4433567_-\|helix-turn-helix-domain-containing-protein	gnl\|CDD\|378935	pfam12728, HTH_17, Helix-turn-helix domain. This domain is a DNA-binding helix-turn-helix domain.	8.40961e-06
NC_010511.1\|WP_012333759.1\|4455166_4457167_+\|glycosyltransferase	gnl\|CDD\|340831	cd03801, GT4_PimA-like, phosphatidyl-myo-inositol mannosyltransferase. This family is most closely related to the GT4 family of glycosyltransferases and named after PimA in Propionibacterium freudenreichii, which is involved in the biosynthesis of phosphatidyl-myo-inositol mannosides (PIM) which are early precursors in the biosynthesis of lipomannans (LM) and lipoarabinomannans (LAM), and catalyzes the addition of a mannosyl residue from GDP-D-mannose (GDP-Man) to the position 2 of the carrier lipid phosphatidyl-myo-inositol (PI) to generate a phosphatidyl-myo-inositol bearing an alpha-1,2-linked mannose residue (PIM1). Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate residue. This group of glycosyltransferases is most closely related to the previously defined glycosyltransferase family 1 (GT1). The members of this family may transfer UDP, ADP, GDP, or CMP linked sugars. The diverse enzymatic activities among members of this family reflect a wide range of biological functions. The protein structure available for this family has the GTB topology, one of the two protein topologies observed for nucleotide-sugar-dependent glycosyltransferases. GTB proteins have distinct N- and C- terminal domains each containing a typical Rossmann fold. The two domains have high structural homology despite minimal sequence homology. The large cleft that separates the two domains includes the catalytic center and permits a high degree of flexibility. The members of this family are found mainly in certain bacteria and archaea.	1.17272e-08
NC_010511.1\|WP_012333747.1\|4440412_4442020_-\|glycosyltransferase	gnl\|CDD\|274425	TIGR03087, stp1, sugar transferase, PEP-CTERM/EpsH1 system associated. Members of this family include a match to the pfam00534 Glycosyl transferases group 1 domain. Nearly all are found in species that encode the PEP-CTERM/exosortase system predicted to act in protein sorting in a number of Gram-negative bacteria. In particular, these transferases are found proximal to a particular variant of exosortase, EpsH1, which appears to travel with a conserved group of genes summarized by Genome Property GenProp0652. The nature of the sugar transferase reaction catalyzed by members of this clade is unknown and may conceivably be variable with respect to substrate by species, but we hypothesize a conserved substrate.	4.08759e-22
NC_010511.1\|WP_012333752.1\|4448727_4449327_-\|hypothetical-protein	gnl\|CDD\|380018	pfam17784, Sulfotransfer_4, Sulfotransferase domain. This family of proteins are distantly related to sulfotransferase enzymes. This protein in S. mansonii has been shown to be involved in resistance to oxamniquine and to have sulfotransferase activity.	4.47377e-19
NC_010511.1\|WP_150108856.1\|4434163_4435327_-\|integrase-arm-type-DNA-binding-domain-containing-protein	gnl\|CDD\|271182	cd00801, INT_P4_C, Bacteriophage P4 integrase, C-terminal catalytic domain. P4-like integrases are found in temperate bacteriophages, integrative plasmids, pathogenicity and symbiosis islands, and other mobile genetic elements. The P4 integrase mediates integrative and excisive site-specific recombination between two sites, called attachment sites, located on the phage genome and the bacterial chromosome. The phage attachment site is often found adjacent to the integrase gene, while the host attachment sites are typically situated near tRNA genes. This family belongs to the superfamily of DNA breaking-rejoining enzymes, which share the same fold in their catalytic domain and the overall reaction mechanism. The catalytic domain contains six conserved active site residues. Their overall reaction mechanism involves cleavage of a single strand of a DNA duplex by nucleophilic attack of a conserved tyrosine to give a 3' phosphotyrosyl protein-DNA adduct. In the second rejoining step, a terminal 5' hydroxyl attacks the covalent adduct to release the enzyme and generate duplex DNA.	7.36343e-48
NC_010511.1\|WP_150108704.1\|4457810_4458038_-\|transposase-domain-containing-protein	gnl\|CDD\|379385	pfam13817, DDE_Tnp_IS66_C, IS66 C-terminal element.	3.002e-07
NC_010511.1\|WP_012333750.1\|4445717_4446893_+\|glycosyltransferase	gnl\|CDD\|340831	cd03801, GT4_PimA-like, phosphatidyl-myo-inositol mannosyltransferase. This family is most closely related to the GT4 family of glycosyltransferases and named after PimA in Propionibacterium freudenreichii, which is involved in the biosynthesis of phosphatidyl-myo-inositol mannosides (PIM) which are early precursors in the biosynthesis of lipomannans (LM) and lipoarabinomannans (LAM), and catalyzes the addition of a mannosyl residue from GDP-D-mannose (GDP-Man) to the position 2 of the carrier lipid phosphatidyl-myo-inositol (PI) to generate a phosphatidyl-myo-inositol bearing an alpha-1,2-linked mannose residue (PIM1). Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate residue. This group of glycosyltransferases is most closely related to the previously defined glycosyltransferase family 1 (GT1). The members of this family may transfer UDP, ADP, GDP, or CMP linked sugars. The diverse enzymatic activities among members of this family reflect a wide range of biological functions. The protein structure available for this family has the GTB topology, one of the two protein topologies observed for nucleotide-sugar-dependent glycosyltransferases. GTB proteins have distinct N- and C- terminal domains each containing a typical Rossmann fold. The two domains have high structural homology despite minimal sequence homology. The large cleft that separates the two domains includes the catalytic center and permits a high degree of flexibility. The members of this family are found mainly in certain bacteria and archaea.	1.97406e-09
NC_010511.1\|WP_012333758.1\|4454237_4455170_+\|glycosyltransferase-family-2-protein	gnl\|CDD\|366154	pfam00535, Glycos_transf_2, Glycosyl transferase family 2. Diverse family, transferring sugar from UDP-glucose, UDP-N-acetyl- galactosamine, GDP-mannose or CDP-abequose, to a range of substrates including cellulose, dolichol phosphate and teichoic acids.	1.00596e-15
NC_010511.1\|WP_150108858.1\|4438560_4440111_-\|hypothetical-protein	gnl\|CDD\|133018	cd02537, GT8_Glycogenin, Glycogenin belongs the GT 8 family and initiates the biosynthesis of glycogen. Glycogenin initiates the biosynthesis of glycogen by incorporating glucose residues through a self-glucosylation reaction at a Tyr residue, and then acts as substrate for chain elongation by glycogen synthase and branching enzyme. It contains a conserved DxD motif and an N-terminal beta-alpha-beta Rossmann-like fold that are common to the nucleotide-binding domains of most glycosyltransferases. The DxD motif is essential for coordination of the catalytic divalent cation, most commonly Mn2+. Glycogenin can be classified as a retaining glycosyltransferase, based on the relative anomeric stereochemistry of the substrate and product in the reaction catalyzed. It is placed in glycosyltransferase family 8 which includes lipopolysaccharide glucose and galactose transferases and galactinol synthases.	7.84289e-05
NC_010511.1\|WP_012333751.1\|4446855_4448226_+\|hypothetical-protein	gnl\|CDD\|226689	COG4238, COG4238, Murein lipoprotein [Cell envelope biogenesis, outer membrane].	0.000908057
NC_010511.1\|WP_150108857.1\|4436673_4438431_+\|hypothetical-protein	gnl\|CDD\|276809	sd00006, TPR, Tetratricopeptide repeat. The Tetratricopeptide repeat (TPR) typically contains 34 amino acids and is found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi, plants, and humans. It is present in a variety of proteins including those involved in chaperone, cell-cycle, transcription, and protein transport complexes. The number of TPR motifs varies among proteins. Those containing 5-6 tandem repeats generate a right-handed helical structure with an amphipathic channel that is thought to accommodate an alpha-helix of a target protein. It has been proposed that TPR proteins preferentially interact with WD-40 repeat proteins, but in many instances several TPR-proteins seem to aggregate to multi-protein complexes.	4.72681e-06
NC_010511.1\|WP_012333748.1\|4442557_4444117_+\|glycosyltransferase	gnl\|CDD\|340831	cd03801, GT4_PimA-like, phosphatidyl-myo-inositol mannosyltransferase. This family is most closely related to the GT4 family of glycosyltransferases and named after PimA in Propionibacterium freudenreichii, which is involved in the biosynthesis of phosphatidyl-myo-inositol mannosides (PIM) which are early precursors in the biosynthesis of lipomannans (LM) and lipoarabinomannans (LAM), and catalyzes the addition of a mannosyl residue from GDP-D-mannose (GDP-Man) to the position 2 of the carrier lipid phosphatidyl-myo-inositol (PI) to generate a phosphatidyl-myo-inositol bearing an alpha-1,2-linked mannose residue (PIM1). Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate residue. This group of glycosyltransferases is most closely related to the previously defined glycosyltransferase family 1 (GT1). The members of this family may transfer UDP, ADP, GDP, or CMP linked sugars. The diverse enzymatic activities among members of this family reflect a wide range of biological functions. The protein structure available for this family has the GTB topology, one of the two protein topologies observed for nucleotide-sugar-dependent glycosyltransferases. GTB proteins have distinct N- and C- terminal domains each containing a typical Rossmann fold. The two domains have high structural homology despite minimal sequence homology. The large cleft that separates the two domains includes the catalytic center and permits a high degree of flexibility. The members of this family are found mainly in certain bacteria and archaea.	2.9982e-23
NC_010511.1\|WP_012333753.1\|4450311_4451289_+\|glycosyltransferase	gnl\|CDD\|223515	COG0438, RfaG, Glycosyltransferase [Cell envelope biogenesis, outer membrane].	1.3649e-08

>NC_010511.1|WP_012333751.1|4446855_4448226_+|hypothetical-protein
MIAEASATKSSPEPRPAVPAHAGRDAGDAAAFPFGRARVLPGHIVLIAETEARLHGPLLALVEGIEIGRSRPLDRCAAGDEVSIPIRRFPFVPLPCEVRFSGEDGLDAAAPIALASEAEAVRLAGPGEVTCDDLRIENGIVTGTLTNAVNGLAVPVLVGQINGVFRQVQVGPLRMRDEGGSTCRLSLALEAGDLTETGATIRVHALPNLAPIAQIGFSRADKDALAEAVTRLEAKVAQLAMRARIDAAGAQRVLEEAVARQQTRLDAMTEYFAALVYDRGAGVPDDQAAAAEVDRVLKAFYETVQRPDDGRAVSSTRNMVRLAPTDPSFGDDWHAPEYFDGVSFRWMPVAATILNPAADRRATGFLVSVFSYLGEVPPDVFVSLDGGEPVRGERIGLVDGQSYTVRIILPSPQHFGVARLISSQARRPSELDPTSHDRRILSFSVTGIRLLLEPDE
>NC_010511.1|WP_012333750.1|4445717_4446893_+|glycosyltransferase
MSRPTSVGAGPRILVVSPMASHPANQGNSLRLLAFNRELMRRGSRIDLVYYGMEGLTPESEAAMRAAWNDFIFVPSRPLGRPSYATHWGIDDWCSDALCEAVERLTAERRYDAVVVNYSWMSRVLEFCDGPVKVLDTHDVFAGRRDKMVEAGLDPRWFFTSVAQEREAFARADIVIGIQEAESGLIAEHCAGRVLTVGHPLALDFLLEEAGTERPLPFGYFASGNPWNKRSALALDAALATRPFRNWAIAGTICDSRLRLRTAPLELGRVAHPREFYDHVDCVVNPMIGGTGLKIKTIEALSHGRSVIGTTAAFEGLRPAHPFHRFASAEALAEGMQDLARDPALRDEVARASRTLAVAYAGAVAAQFDMLIASIEDLAHDRRSQRHEELA
>NC_010511.1|WP_012333749.1|4444155_4445721_+|hypothetical-protein
MASLRSILSVVRAFRSADARSLIESGLFDAAWYRKRYPAARRGLVSHYLASGAAEGHWPNPLFDPVWYATAYPEAVADGTLPILSYLRDGLATDRRPNPVFDTRWYLERYPDVRDYRFHPLVHYLRHGVEDGRDPSPDFSTLWYLEQNPDVRNAGEHPLVHYLHFGMHEGRAPRPASPGDRAAVHRTEPLTRLEAMVRRAQAGETEPADRADPVFRSLAEAVAAIRLRDPDARFVDATYPDHVLPGLVPDAVLAGPAALLAQEGPLGFYAAFRQQGGRQPIFVGGLPRRPPPHEWVYVGACDALPPRLGPALAARSFLVRDEPDRIAQVAARAPAEIDSLDLGPPDAEGLGVAALLAPGRRAALTEPVGTAELPNLDRILLLPDHAVSTPGEVETAGDFSWIWCGPDRIQRFALGRRPFPRTTIGIAFRAADVGIGSRCRDLLRFQVNGRTVEAVVAVSGRDGAALIAVPPAGPAGPLTLSIGCRDGVRAPGDPRRLTVHVTAITLTPARPETASQEIAAR
>NC_010511.1|WP_012333748.1|4442557_4444117_+|glycosyltransferase
MDPYRVGPDRKALEELFFFSPLPPSRNGIADYATRVLAELSSHYDVTAFSDSLFSEVPPGVTLADEACAFQYLRPGAKNVYQIGNNPGHVFVLRAALRHPGVVVLHDPRLLYLYQTAGTSTQDLYDLMAASNPRAAELVRAARVDGRGPTRADHVLFDALADVVRASRAVVVHSDYARQLIRKQHGDVADKVVVIPHFAYPPVTLARAAARAAMNVAADAFVVITAGFVHRRKRYEWLIEGLDQALQTIRQPVVWIQAGELREEEVPLAELLDLHPAVKAVSRVTGYLSESDLDTAVAAADVLVNLRFPSEGESSGSLARAFGNGTCCLVSDTAAFREIPDDVAIRIPTVDAPRAIAAALDALAAAPALRDAFGARAARYAATELSMSRYGERLRGVLDRLDAFPVTAAAPAGAALPTLRLPPDPASARARLEAQLAAHPAGMSVEIGPIQALVDARAILASVLPGGAEARHVRVVPVSADGPADEASYQLRLHVSRQAVSRTQAVSRTQAVPRPPATA
>NC_010511.1|WP_012333747.1|4440412_4442020_-|glycosyltransferase
MFDVDWYRRTYPDVSASGADPIRHYVDHGSREGRMPNPLFRPHWYLDSYPHVRTADVNPLVHYIRHGVEHGLKPHPLFDTAWYDASYPDAAAAGLHPLAHFLTRNEDSRYNPNPLFDLASYIDSHSLPLDSNIAALEHYMGTDENLSGRTARPGPASTRAGNGPKLLVIDGVYPRPNRDSGSLDAFNFLRIFLNMGFRITFIASAEFQDDNCYRRQIENIGVYGVDYYKYKSVEDFLARCGKNFDVFFLSRVHCGGNYYKFARKSSQSAKIIFNTVDLHHVREQREALLNDDRVSLNRSQWTREREYYLSRMCDATIVVSSLEARLLRENVPGANVHVVPLLRDLAEPRAGFDARDGVGFIGGFGHTPNVDALLFLLDEIWPLVSGRDEAIKLYVLGSDLPPRFRLRRDRNVVYVGYVEDIGERLEGLRVMVAPLRYGAGAKGKIVSSLIHGVPTVATSVAAEGMDLVAGRDVMVSDSPEEFAEAVCRLHRDRGLWEHISASGYRRAAEVHDVSRGAEIMGRILGSAGVALRAQP
>NC_010511.1|WP_150108858.1|4438560_4440111_-|hypothetical-protein
MGYALTLRETILAHEKDATFYLLLCDREDSVDAGMYDFEIIYIDQLGVPNLENMKQNYNITELNTSLKPFMFLYLFDRHPGSRVVYLDPDIMVLSPLDELRSCLDEGAACVLTPHITEPAEFADMNDGMFLLYGIYNLGFCCFADTPQVRRVVSWWSRRLESDCSIDLPRGRFVDQKWADLLPAMIDNTFILRHVGYNVAYWNLSQRRLSRTDGTWSVNGFPLRFFHFSGNIIEDEAVFSRHSHEFNIHSFGVIGELLTQYRSLIYKNGHRYYSSLQYGFNWSGASGRNEHTLLEIFENRPKHAASPHLHLTPRGDRPNLPDAVRTVRASAEARLAEAARAAALTGHCIRCGGRTDFVLEQEAVAGSPGTRTRVVCTGCELDAARRVGIHVGRQLLRSDGAEITYPSGTGDAVVATMRATEPGCGLGGAASLCVVSVPRDAPSAVDVTALCAQYDRVVAVHTDESFESAARSRGAQVSVRDAWSETCLYVFEPTSVAILERSEADPRPPAAGESAA
>NC_010511.1|WP_150108857.1|4436673_4438431_+|hypothetical-protein
MSGYLQANPDVAAANINPLVHFWAFGLAEGRSGWQVAEAATAFQEGRYKDALSASNRIAETSPGLPGAYYWGSLAGIYDGDFRGVCDLGMRAIKNGIAEPLVLTALGTAFWRLDLPDFALIAHERAFKLDPGSSHVRLGLARACIRMGDLQRAIDVAGPMGDHLAPDRSTSFELTTAEELALSNLTWPFGIYQAGISAFRREDWDTAVHHFSRAFHLFLTQQNVNMIDICGEYYCNAKICSENKSGLRAISDAASPFLPDARWPKVYAGAQDLLEGRTDDGLRKIVEAQPLPPRELGDLLGLNSLLLPEAVTLSRRERSPRLSSGAVSDFRAAQARVGSGRAILAACDGTYFSKLSNLYVGSLNIVAPGSHLHFHIMNPLDSTEALIGHLRTRYRDVEISFSRENIDKSDKNLKAIYATRRFEVAFELIQKLSVNLLVTDVDISFESPVADFISKLRGSDVGLMFEGRVLPWFSNPATIAFFSNTPSSLKFLSYVNSYVALAFASLRDTNIWFVDQNALYVSRQIMGSSLQIANLNSIEPGIFGCYTTEGRDLYTERRSRELGLSDPDGAPETVTAAARAGGGRL
>NC_010511.1|WP_150108856.1|4434163_4435327_-|integrase-arm-type-DNA-binding-domain-containing-protein
MKRLSARSVATITKPGRHADGDGLYLVVDPSGAKRWLFLFRWHGKLKEMGLGGLSTVSLAEAREAASEARRLVKSGRNPIEQRRAAKSDEAALVTFGAFADKVVTDLAPGFRNDKHKAQWAMTLTTYAAPLRPMPVEAIGTEDVLRVLEPIWQTKSETASRLRGRIERVLDAAKAKGLRTGENPARWRGHLDKLLPARRKLTRGHHAAMPFEDVPAFLAALREREAAAALALEFCILNASRSGEVLGSCWGEIDRKAKVWIVPAERMKAGREHRVPLTSRALEILDHVEAVRAGDLVFPGQKRNRPLSVMAMEMLLRRMQVPYTVHGFRSSFRDWAGERTSYPREIAETALAHVVGDATERAYRRGDALEKRRKLMEEWAAYCAKGE
>NC_010511.1|WP_150108702.1|4433571_4433901_+|hypothetical-protein
MLLNVAGQSGVQEHGNEPPLPLRKIYSEFKFAIANVALEALKQGSHFLNTRLNHARRYVLSKMSRIILRHAFDKTLAKSVRSNYSARYNATSIKFTIDFILNITTDVIY
>NC_010511.1|WP_012333743.1|4433375_4433567_-|helix-turn-helix-domain-containing-protein
MSEKRAHTIAEVVQISGAGRTTIYAEIAAQRLKAKKLGRRTLIMSDDLEAWLSNLPDLKSRAA
>NC_010511.1|WP_012333752.1|4448727_4449327_-|hypothetical-protein
MTELLRSRKVFVASLHRCGTQSVHRLLCDLGLKSIHWPKFYDGIDLEEEIRGREADRWHVSYSLNKVLYEHDAVSDVPICGIYDVLARRFPSSQFIVLHRPAEDWIRSVRRHIGRRDFDPYEKVVYTRYLHDLPQKISDVSDGSLKAVMEQHAAEVYDFFRGTGQLLMTDLGSPSVGRDICEFLGRVPIPFMKVDYQPT
>NC_010511.1|WP_012333753.1|4450311_4451289_+|glycosyltransferase
MKFVRATILSDDPLIIFTGGSGDAPVSGSSLLAEPLRDRKVTFLILTLWSAESNDHADNLMNFVKKYEADYPNHEYIVFCNTQAEVENLARRGVRAYFGQQNSFIDPNVYKPIDGIPKDLQAVYTAQLHPFKRHALCADLDSVGLVYHSFGEETRAYYSELKQQIPGARFMNEELTSPPHGNLSAPEVVTIMNRAHVGLCLSAEEGGMHASVEYLLTGLPVVSTPSKGGRDFFFDNSFVEIVDPTPADVARGVREIIGRAPPAQEIRNRTIDLQRKQIALFQDYLDGLVKQNGGSGYDRSLWNARYRDKLLGWETLDEVLKRIPA
>NC_010511.1|WP_012333755.1|4452679_4453132_+|hypothetical-protein
MQDLDWSTFEVMLADARLSGDGRRWLSQSDRRADAGIRAHVVRSGRPSPIPPPSLRGVAVLTQIRRLLGAASPTSRSSPRAPRAAWGRRGRRGGEPEPAGDAVGLPGRGCAQRRGISREPPAPCGGPLVESNDGQYVLRLAKSDNVPYLG
>NC_010511.1|WP_012333756.1|4453189_4453681_+|hypothetical-protein
MRAQETQELRFENDASFEIVSEAPRDVRIRASDQLDKSNGLHFREWTRPAGDCFRWSGARDSVRLPIRIERGAGVDIDVEVMGTACNPAQARLRADGIDVPTPDGSAAEGYFHLRASLPPVVGQSLILEISSATRPESQEPGGRNLGLAILSVRVVSKDIAHG
>NC_010511.1|WP_012333757.1|4453730_4454234_+|hypothetical-protein
MQRLSQVEARQTELESALEKNLGAVDAAVRAAFDAATTASLMANWSFDARMPNTLSGNLSLPERDASGRWVRWLLGMPRLEWTVQVTPNRQYDLTVVVPKFVSRRAYDGLYVRANGEDLPWLSWDGAVRGTIVGAGQDGVLKLALAVPETEEADAPFAVASINLKVR
>NC_010511.1|WP_012333758.1|4454237_4455170_+|glycosyltransferase-family-2-protein
MSDNARLTVAICTFDRYDLLNRTVSTLLERDRIDGHQAELLIVDNTPLARRRPIALPEGRGSRVTFCDETGLSHARNLAIDEANGEIIAFLDDDALVCSGWTTQLLNAFDAHPDALIVGGRVVPLYENADRLPEWYDDRLASHLSCIDWSDTGRFLNENEWVVGANLAIRKDVFRQYGRFDPSLGRRGTASLLSNEETALLDRVGRHRTFYCPEACVEHIIAADRLTPEHFRRRVFWQAISDVVSGSCWMTLDLAYERYKTRMVLAPPQYRNIKALSYLPRTSAEFVVQLESIYAMAMIASAGFKQGEDA
>NC_010511.1|WP_012333759.1|4455166_4457167_+|glycosyltransferase
MTVPATSPNRFGQTVLFITPFASHPANSGQRRRVFQIASLLKRAGFRITFVLYAFELPWYWYFDQISYQEMVNTWGEVHIYPASKQVGLPPQDGNFHSLDEWWDPAFEKFLERLNEIKTFDVTVVTNVWMTKAFYSAFNSFKILDTLDVFSKRQQIANRTGIAPEFFWTDERNEMFGWSRADLVVTVTDEEKSYFGDKITVPVHNIPIVLAEAAAKKTRRSYIHDDRVVFGVLSSAQVYTVIGLNAVLQELELQVEEDFSPVDLIIGGTISDHVKTNLPVQRLGEVASEEEFLGRVDFIIAPQFDGTGFKVKVADAMLAGIPVLAAEHSSIGTGLPDSFVFSSPKTLARAMSRIALDRPPLSRFLDAVEAAAADLVAARERSEAELIASIERACGLLVLDVRGLSAEEHWPILASYVSWSRILSDRMRVFFLVDDNLKRIIGRLRNRWYEIVGEADLPDLKTSGKMVVALGPLRANDLSRSVRDGRWDWLLGEQVVSDPGDDAVSQLPFLHSDIDWLPGVMTMIRGRGDLAATDKAGERIAGPSVARVTVVENSELARALPRAGRSSDVIIALSDRGMFNNLIAELLCGGRDSGPELAWIGRAGAPAERLLHEIASRCSLKFTGSTICGRSSYDDVEKYARALLSGVAMPLERHPITLQSGAALDL
>NC_010511.1|WP_012333760.1|4457563_4457794_+|hypothetical-protein
MQIDEERIDEAVLGLPWLTLHDERRAWKGFDWQVLDRLHRKGLIADPVGRAKSVVLTDEGLRRSRALFHALFTRAT
>NC_010511.1|WP_150108704.1|4457810_4458038_-|transposase-domain-containing-protein
MPIPFAIPECRFERVVEHHRDRLVIPVRLNDVDPRAWLADVLARINDHPSRALAAPLPRAWKARGPAMASSAQVA
>NC_010511.1|WP_012333762.1|4458121_4458769_-|hypothetical-protein
MHTLDVAVLTALVVLGVSLAYAWRRERRHRQRNLASALVGEIVAVLRAIETHDVLARLEHVAATVPRVAVPTLPPIPAAVYQAYAGCLDRLEAPLPRKISYFYTRLQMLQGDLAALSLRQVQDFPAVSGASFAAELARDLRDTLAVGDEILKDLRPLLVRRRLHIRLRRTVASTAKVYRKLPRATLRHPFAHRPPGAPLWPWRRGAAPASPAQPL

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Crispr_ID: NC_010511_29

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_010511_29

4808266-4808359

Orphan

Consensus_repeat	Method
GCCTGCGCGGCGCCTGAGCGAAGCC	CRISPRCasFinder

1 spacers

csa3

The CRISPR arrays of NC_010511_29

>merge|NC_010511|29|4808266-4808359|CRISPRCasFinder
GCCTGCGCGGCGCCTGAGCGAAGCCCAAATCCGCCATCCCGAAGGGATCAAGCGGATTTGGTATGACACGCCCGCGCGGCGCCTGAGCGAAGCC

>NC_010511|29|29|4808266-4808359|CRISPRCasFinder
GCCTGCGCGGCGCCTGAGCGAAGCC	CAAATCCGCCATCCCGAAGGGATCAAGCGGATTTGGTATGACAC
GCCCGCGCGGCGCCTGAGCGAAGCC

Protein	Signature genes	Signature genes Name	Protein_function
NC_010511.1\|WP_012334099.1\|4814648_4815044_+\|hypothetical-protein	unknown	unknown	unknown
NC_010511.1\|WP_012334097.1\|4809638_4810559_+\|methylenetetrahydrofolate-reductase-[NAD(P)H]	unknown	unknown	gnl\|CDD\|273212
NC_010511.1\|WP_012334104.1\|4818691_4819717_+\|TerC-family-protein	unknown	unknown	gnl\|CDD\|274743
NC_010511.1\|WP_012334086.1\|4800002_4800407_+\|DUF2147-domain-containing-protein	unknown	unknown	gnl\|CDD\|378304
NC_010511.1\|WP_150108712.1\|4800738_4801974_+\|PAS-domain-containing-protein	unknown	unknown	gnl\|CDD\|214599
NC_010511.1\|WP_012334105.1\|4820091_4821285_-\|aminotransferase-class-V-fold-PLP-dependent-enzyme	unknown	unknown	gnl\|CDD\|178031
NC_010511.1\|WP_012334103.1\|4817301_4818516_-\|TIGR03862-family-flavoprotein	unknown	unknown	gnl\|CDD\|274820
NC_010511.1\|WP_012334100.1\|4815097_4815310_-\|hypothetical-protein	unknown	unknown	unknown
NC_010511.1\|WP_012334090.1\|4803105_4803342_-\|hypothetical-protein	unknown	unknown	unknown
NC_010511.1\|WP_012334101.1\|4815479_4816025_+\|formaldehyde-activating-enzyme	unknown	unknown	gnl\|CDD\|378034
NC_010511.1\|WP_012334092.1\|4804301_4804799_-\|DUF2147-domain-containing-protein	unknown	unknown	gnl\|CDD\|378304
NC_010511.1\|WP_012334102.1\|4816157_4817192_+\|collagen-like-protein	unknown	unknown	gnl\|CDD\|236090
NC_010511.1\|WP_012334089.1\|4802503_4802992_+\|GNAT-family-N-acetyltransferase	unknown	unknown	gnl\|CDD\|182266
NC_010511.1\|WP_012334088.1\|4801981_4802404_-\|DUF4345-domain-containing-protein	unknown	unknown	gnl\|CDD\|372978
NC_010511.1\|WP_012334091.1\|4803589_4804258_+\|thiol:disulfide-oxidoreductase	unknown	unknown	gnl\|CDD\|172475
NC_010511.1\|WP_012334095.1\|4807869_4808226_+\|hypothetical-protein	unknown	unknown	unknown
NC_010511.1\|WP_012334094.1\|4805616_4807716_+\|molybdopterin-oxidoreductase-family-protein	unknown	unknown	gnl\|CDD\|239167
NC_010511.1\|WP_012334096.1\|4808569_4809553_+\|metalloregulator-ArsR/SmtB-family-transcription-factor	csa3	COG0640_csa3_CAS-I-A	gnl\|CDD\|225136
NC_010511.1\|WP_012334098.1\|4810761_4814505_+\|methionine-synthase	unknown	unknown	gnl\|CDD\|236539
NC_010511.1\|WP_012334093.1\|4805072_4805495_+\|nucleoside-diphosphate-kinase	unknown	unknown	gnl\|CDD\|179085

Protein	Function_ID	Function_description	E-value
NC_010511.1\|WP_012334097.1\|4809638_4810559_+\|methylenetetrahydrofolate-reductase-[NAD(P)H]	gnl\|CDD\|273212	TIGR00676, 510-methylenetetrahydrofolate_reductase., 5,10-methylenetetrahydrofolate reductase, prokaryotic form. The enzyme activities methylenetetrahydrofolate reductase (EC 1.5.1.20) and 5,10-methylenetetrahydrofolate reductase (FADH) (EC 1.7.99.5) differ in that 1.5.1.20 (assigned in many eukaryotes) is defined to use NADP+ as an acceptor, while 1.7.99.5 (assigned in many bacteria) is flexible with respect to the acceptor; both convert 5-methyltetrahydrofolate to 5,10-methylenetetrahydrofolate. From a larger set of proteins assigned as 1.5.1.20 and 1.7.99.5, this model describes the subset of proteins found in bacteria, and currently designated 1.7.99.5. This protein is an FAD-containing flavoprotein. [Amino acid biosynthesis, Aspartate family].	2.2201e-140
NC_010511.1\|WP_012334104.1\|4818691_4819717_+\|TerC-family-protein	gnl\|CDD\|274743	TIGR03718, R_switched_Alx, integral membrane protein, TerC family. Rfam model RF00080 describes a structured RNA element called the yybP-ykoY leader, or SraF, which may precede one or several genes in a genome. Members of this highly hydrophobic protein family often are preceded by a yybP-ykoY leader, which may serve as a riboswitch. From the larger group of TerC homologs (pfam03741), this subfamily contains TerC itself from Alcaligenes sp. plasmid IncHI2 pMER610 and from Proteus mirabilis. It also contains the alkaline-inducible E. coli protein Alx, which unlike the two TerC examples is preceded by a yybP-ykoY leader.	5.47615e-132
NC_010511.1\|WP_012334086.1\|4800002_4800407_+\|DUF2147-domain-containing-protein	gnl\|CDD\|378304	pfam09917, DUF2147, Uncharacterized protein conserved in bacteria (DUF2147). This domain, found in various hypothetical prokaryotic proteins, has no known function.	3.18946e-38
NC_010511.1\|WP_150108712.1\|4800738_4801974_+\|PAS-domain-containing-protein	gnl\|CDD\|214599	smart00283, MA, Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). Thought to undergo reversible methylation in response to attractants or repellants during bacterial chemotaxis.	1.49611e-39
NC_010511.1\|WP_012334105.1\|4820091_4821285_-\|aminotransferase-class-V-fold-PLP-dependent-enzyme	gnl\|CDD\|178031	PLN02409, PLN02409, serine--glyoxylate aminotransaminase.	2.01396e-133
NC_010511.1\|WP_012334103.1\|4817301_4818516_-\|TIGR03862-family-flavoprotein	gnl\|CDD\|274820	TIGR03862, flavo_PP4765, uncharacterized flavoprotein, PP_4765 family. This model describes a sharply distinctive clade of proteins within the larger family of flavoproteins described by pfam03486 and TIGRFAMs model TIGR00275. The function is unknown.	1.7789e-149
NC_010511.1\|WP_012334092.1\|4804301_4804799_-\|DUF2147-domain-containing-protein	gnl\|CDD\|378304	pfam09917, DUF2147, Uncharacterized protein conserved in bacteria (DUF2147). This domain, found in various hypothetical prokaryotic proteins, has no known function.	1.08355e-36
NC_010511.1\|WP_012334102.1\|4816157_4817192_+\|collagen-like-protein	gnl\|CDD\|236090	PRK07764, PRK07764, DNA polymerase III subunits gamma and tau; Validated.	4.8943e-08
NC_010511.1\|WP_012334089.1\|4802503_4802992_+\|GNAT-family-N-acetyltransferase	gnl\|CDD\|182266	PRK10146, PRK10146, aminoalkylphosphonate N-acetyltransferase.	2.8814e-14
NC_010511.1\|WP_012334088.1\|4801981_4802404_-\|DUF4345-domain-containing-protein	gnl\|CDD\|372978	pfam14248, DUF4345, Domain of unknown function (DUF4345). This family of proteins is found in bacteria, archaea and eukaryotes. Proteins in this family are typically between 125 and 141 amino acids in length. There is a single completely conserved residue E that may be functionally important.	5.37495e-19
NC_010511.1\|WP_012334091.1\|4803589_4804258_+\|thiol:disulfide-oxidoreductase	gnl\|CDD\|172475	PRK13972, PRK13972, GSH-dependent disulfide bond oxidoreductase; Provisional.	3.3845e-68
NC_010511.1\|WP_012334101.1\|4815479_4816025_+\|formaldehyde-activating-enzyme	gnl\|CDD\|378034	pfam08714, Fae, Formaldehyde-activating enzyme (Fae). Formaldehyde-activating enzyme is an enzyme required for energy metabolism and formaldehyde detoxification. It catalyzes the condensation of formaldehyde and tetrahydromethanopterin to methylene tetrahydromethanopterin.	3.28758e-71
NC_010511.1\|WP_012334094.1\|4805616_4807716_+\|molybdopterin-oxidoreductase-family-protein	gnl\|CDD\|239167	cd02766, MopB_3, The MopB_3 CD includes a group of related uncharacterized bacterial and archaeal molybdopterin-binding oxidoreductase-like domains with a putative N-terminal iron-sulfur [4Fe-4S] cluster binding site and molybdopterin cofactor binding site. These members belong to the molybdopterin_binding (MopB) superfamily of proteins.	0
NC_010511.1\|WP_012334096.1\|4808569_4809553_+\|metalloregulator-ArsR/SmtB-family-transcription-factor	gnl\|CDD\|225136	COG2226, UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis [Coenzyme metabolism].	2.76679e-27
NC_010511.1\|WP_012334098.1\|4810761_4814505_+\|methionine-synthase	gnl\|CDD\|236539	PRK09490, metH, B12-dependent methionine synthase; Provisional.	0
NC_010511.1\|WP_012334093.1\|4805072_4805495_+\|nucleoside-diphosphate-kinase	gnl\|CDD\|179085	PRK00668, ndk, mulitfunctional nucleoside diphosphate kinase/apyrimidinic endonuclease/3'-; Validated.	1.29524e-85

>NC_010511.1|WP_012334095.1|4807869_4808226_+|hypothetical-protein
MRLRIALAAGLLALGASAALAGGTAAPLEAYQPDPALRTAPKTELESRVRNACAVVQARLQNAAETALERPCGCYARATLRALDPAELEAYRSTGYFNESARAKALSALDSCKLPRPI
>NC_010511.1|WP_012334094.1|4805616_4807716_+|molybdopterin-oxidoreductase-family-protein
MTAQARIERRASTCPHDCPSVCALDVEVIDGAAIGRVRGAARHSYTAGVVCAKVARYAERVHHPDRLTRPMIRTGPKGSGSFAPISWDEALDRTAEAFLGAEAAHGPEAVWPYYYAGTMGLVMRDGINRLRHAKGYSGQHSTICTTLAWSGFVAGTGRLAGSDPREMAESDCIVIWGTNPVHTQVNVMTHVQAARRNRGATLVVVDIYDNPTMRQADMALLVRPGTDAALACAVMHVLFRDGHADRDYLARYTDCPAALEAHLRPRGPDWAAAITGLTVAEIEAFARLVGATKRSFFRLGYGFSRSRNGAVSMHAALSIPAVTGAWQHPGGGAFHSNSGIYGLDKTLIEGLDARDPRVRVLDQSQIGRVLCGDAEALRGGPPVTALLVQNTNPVSVAPEQEAVKRGFARDDLFVCVHEQFLTETARMADIVLPATMFLEHDDLYTSGGHQHIQLGPRLIAPPEGCRSNHEVVAALAARVGAAHPGFALSPRDLIDATLRASGRGSLAELEAAGGILDAQPPFARAHYLDGFGHPDGRFRFRPDWGAVPIGHDGPRGPAADLPALPDHWEAPLRTATPAHPFRLATSPARNFLNSTFTETPTSRAKERHPTVMIHPEDAAAHGIGEGTWVRLSNELGAVTLRATLCPGLRRGVLIAESIWPNDAYPDGRGINTLTGADAPAPFGGAAFHDNHVAIAPVAG
>NC_010511.1|WP_012334093.1|4805072_4805495_+|nucleoside-diphosphate-kinase
MAIERTFSILKPDATARNLTGAINAVIEEAGLRIVAQRRIRMSEAQAKTFYEVHAERPFYGELVSFMTSGPVVVQVLEGDNAVAKYREVMGATNPAQAAEGTIRKRFAVSVGENSVHGSDSAENAAIEIAQFFTEADIVG
>NC_010511.1|WP_012334092.1|4804301_4804799_-|DUF2147-domain-containing-protein
MRSVRTPALTAFLLLAGTAAQAGTDPSGTWLTEDGRAKIKIERCGPAGSQACGTVVWLKVPLNDQGQPRTDIKNPDPKKRQRPVIGLQLMEGLKPDEAGYKGQIYNAEEGKFYEVTIARESASELSISGCLLKVLCGSQTWTKAPDEVAQAAPAKPAAKPKTVTP
>NC_010511.1|WP_012334091.1|4803589_4804258_+|thiol:disulfide-oxidoreductase
MSAVTTPPIDLYYWTTPNGWKASIMLEECGLPYRMIPVNIGKGAQRAPEFLSVSPNGKIPVIVDHDGPGSAPITIYESNAILQYLARKTGQFYPEAERERIAVDIWLFWQAANFGPVLGQTHHFRIYAPEKIPYAIERYTAEAARLYRVLDAQLAAHAFVAGDAYTIADIAVVTWAKLWERQGLDIADYPHVGRWLDAVKARPAVLRGFKLRAEPENAAAPA
>NC_010511.1|WP_012334090.1|4803105_4803342_-|hypothetical-protein
MRSRLVLAALVAAVLAPPLPARAQERAEPTVKGMAARERQKKCGAEWRALSTADKAAQGPTWPKYFSKCVKRLKEQKA
>NC_010511.1|WP_012334089.1|4802503_4802992_+|GNAT-family-N-acetyltransferase
MRTPEMSAPEMPALAIRVAVPDDLEAIVRLHEADAVGGHGDAWTPENRPAYAAALAAIAASPDCDLYVVLEGGEVVGSFQLSFRQGITSRGARQAVLESVQVRADRRSRGVGARMVEEAERLARAGGATSLQLTSNKRRVDAHRFYERLGYARSHEGFRKPL
>NC_010511.1|WP_012334088.1|4801981_4802404_-|DUF4345-domain-containing-protein
MDKERRLLQRVVALAALVPVAGGLYGVVFGAGGIGGERVAVSVDSHFRYLSGLLLGIGLLFWSTVPEIEQRTRLFRFLTLVVVLGGLGRLLGLWLTGVPSLVMLAALGMELLVTPLLCLWQARVARMAARSGRAAGPGEL
>NC_010511.1|WP_150108712.1|4800738_4801974_+|PAS-domain-containing-protein
MGRYAGVGLWDAVLHEGDPMHPKSRWTWSEQFRRLLGYASREEFPDMVTSWSERLHLEDAARTFAVFKAALANVRDKGNYDVTYRLRMRDGSYRWFRATGGVAHGLDGTPLRACGSLVDIHAGVVAEGERGRRVEALLGEFDRDAVAMLEAFARSASGMEETAHAMTSIADRVRTGSGHVATASGETSAGVERVAEATEEIAATIRQLSERAAHASDLSTSVAEKAARTDGMVQDLSRAADRIGAVVGMIAALAHQTNLLALNAAIEAARAGSAGRGFAVVAAEVKELAGETAKATDQIAAQIAEIREATGTTVRAIGEIGRSITELRDTNLDMVRAMRQQGAVTSDVAQTLARTASGSRLVSENIVAVREVAEEAGRTADAVLGSARGLARYSGELGDRLRGFLTAVRAA
>NC_010511.1|WP_012334086.1|4800002_4800407_+|DUF2147-domain-containing-protein
MYRGLIALLALTMPALAQPRLDPSGTWLTAGGDAHIRITRCGQGYCSTVAKVLTGEAKDVHNPDPALRARSMVGVALSTDMRPTGEGWEGSLYNFRDGKTYTGKLAVKGPNALELAGCVLGGLICKRQIWSRVN
>NC_010511.1|WP_012334096.1|4808569_4809553_+|metalloregulator-ArsR/SmtB-family-transcription-factor
MIQPLAFSDALGVLRAAAEETRLRIIALLREGELTVSDLTDILGQSQPRISRHLKLMVEAGLVERHREGAWAFFRLVEGVSAMVEPLLAAADRTRPPLSEDRARLDAVRAQRAEAAQSFFARLAPQWDKVRSLHVPEATVEAAVLDVLGPRPIGSLLDLGTGTGRMLALLAPRATRATGLDANHAMLSVARANLERQGLARVDLRQGDIHAPPFSRGSFDLVLIHQVLHYLDDPARALREAARLVAPGGRLLVVDFAPHDLEFLRETQAHRRLGFAAEQVAHWLTEASLDDVTLRELPPSSEAGHRLTVTLWLAHNPAAAIPTREVA
>NC_010511.1|WP_012334097.1|4809638_4810559_+|methylenetetrahydrofolate-reductase-[NAD(P)H]
MVSTAFRPSRESRRPIRVSFEFFPPKTTEMEETLWSSIERLAPLQPNFVSVTYGAGGSTRERTHNTVARLVRETSLKPAAHLTCVAATQEEVDEVVRSYWDAGVRHIVALRGDPAEGVGTAYRAHPGGYARSCDLVAGIKRIGDFQVSVSAYPERHPEAPSLDADIDALKAKVDNGADRAITQFFFDNDLFFRYLDRVQARGIDIPIIPGILPVQNFKQAASFAKRTGASVPEWLAARFEGLEDDVGTRKLVAAAVAAEQVLDLVDRGVTDFHFYTMNRADLVYAICHLLGLRALPSAPVAEKAAA
>NC_010511.1|WP_012334098.1|4810761_4814505_+|methionine-synthase
MTDLRPADGANVLATLRKRAAERILVLDGAMGTMIQRLKLGEADFRGKRFLDHAHDQRGNNDLLILTQPEAIRQIHLDYFLAGADVVETNTFSGTAIAQADYGMEAIVRELNREGARLAREAAVEAERRDGRRRFVAGAIGPTNRTLSISPDVNNPGYRSVTFDQVRDAYAEQVRGLIEGGSDLVLIETIFDTLNAKAAIAATWQVFGEMGVRLPIMISGTITDLSGRTLSGQTPSAFWHSLRHAEPLTFGLNCALGAREMRAHISELSRVCDTLVCAYPNAGLPNEFGLYDESPEAMGALVGEFAGSGLVNMVGGCCGTTPDHIRAIAEAVAGKAPRRVPEVPRLMRLSGLEPFTLTKEIPFVNVGERTNVTGSAKFRKLVTSGDYAAALDVARDQVAAGAQVIDVNMDEGLLDSRAAMVEFLNLVAAEPDIARVPVMVDSSKFEVIEAGLKCIQGKPIVNSISLKEGKEKFLTEARICRAYGAAVVVMAFDEQGQADTLERKVAICTRAYRILTEEVGFPPEDIIFDPNIFAVATGIEEHDGYGVAFIEAARQIRETLPHAHISGGVSNLSFAFRGNEPVREAMHAVFLYHAIRAGMDMGIVNAGQLAVYDELDPELRDLCEDVVLNRRPDATERLLEQAAKFKGGGAQLRTADLAWREAPVEKRLEHALVNGITEYIEADTEEARRTATRPLDVIEGPLMAGMNVVGDLFGSGKMFLPQVVKSARVMKQAVAYLMPFMEEEKRANGGTGRQAAGKVLMATVKGDVHDIGKNIVGVVLACNNYEIIDLGVMVPAAKILDTARKEKVDIVGLSGLITPSLDEMVHVASEMEREGFEVPLLIGGATTSRVHTAVKIHPAYAKGQAVYVTDASRAVGVVSSLLSPETKAATIEGVRAEYKRVAEAHARSEADKQRLPLAKARANPFRAEFSTYRPAKPSFTGTRVFRSYDVAELVPYIDWTPFLQTYEFKGRFPALLDDPVQGPAARALFDDAQAMLARIVEERWFNPKAVIGFWPANAVGDDIRLFTGESRTDRLATFHGLRQQLSKRDGRPNTCLSDFVAPLDSGVPDYVGGFVVTAGLEEVRIAERFERQNDDYRSILVKALADRIAEAFAERMHERVRKEFWGYAADETFAPADLVLEEYQGIRPAPGYPAQPDHTEKATLFDLLQAEPRIGVKLTESYAMWPGSSVSGLYLAHPGAHYFGVAKVERDQVEDYAARKGMDVAEVERWLGPILNYDPRRHLAAAE
>NC_010511.1|WP_012334099.1|4814648_4815044_+|hypothetical-protein
MVASLAVLASSGCVEFGYVSQTYASLRPQVVTIGCNDPYEVFDERQTRRMLIVSNGLREVAGCGLDGADPALTRRKRFRDAAVTYLSETDRETCRITAETVFDDLRTEFAYACAEPVEKPGTKVRRLPGRT
>NC_010511.1|WP_012334100.1|4815097_4815310_-|hypothetical-protein
MSERDWTLRVTPTEAGVQVEFGLSELGGEPVTAVIALDRGEARRFARALLAAAGDAAERTFPHPKPTGQG
>NC_010511.1|WP_012334101.1|4815479_4816025_+|formaldehyde-activating-enzyme
MSEILFRTGEATVLAAEGQFTDAMPEVLIGSVRGPVGTAFASMMGQVQGHTRMFVVRDLNQLVRPATMMTTKATIQSADYVELLGGVVQAATGDAIVDCVIEGILPKQGLDELCMIIMIWLDPRCADDANLDRKDLYRTNYEATKLAIARALKGEPTIEELIANRKTVKHYALEDVIDYEA
>NC_010511.1|WP_012334102.1|4816157_4817192_+|collagen-like-protein
MRLRRAVLVLSTLVLIGSGPAFAQGEAAPAPAAPKPEAPRGAARKPASSAIQIWDARIEGGDLRISGNVGKAGVTVSLDDEVAVQSDRRGRFAIKVPYVPQTCVATLTAGEESREVAVANCAPQGQPGPAGQPGPTGPQGVAGLPGPKGDPGPQGPAGPKGEPGPKGEPGPKGEPGPKGEPGPKGEPGPKGEPGPKGEPGPKGEPGPRGEAGPQGALGPKGEAGSRGEPGPRGEPGPKGEAGLAGAPGPKGEAGPRGPQGERGPPGAPGAAAPVAAATALPMRVLRSETCATGSCELACEGGETLLSAYCVRAGAPTFTRREGGQAAAFCPSESAGIVAVCAKL
>NC_010511.1|WP_012334103.1|4817301_4818516_-|TIGR03862-family-flavoprotein
MTDARVAVIGAGPAGLFAAETLARAGCAVTVIERMPSPARKLLIAGRGGLNLTHSEPLEEFLARYHPAGGAVAAAIRAFPPDALRAWCEELGQPTFVGSSGRVFPTAFKASPLLRAWLARLAASGVALRTRTRWIGFAPHGGLRLAGPEGEAILAADATLLALGGGSWPRLGSDGSWVPLLREAGIPVAPLRPANAGFRVEWSEPFASRFAGAPLKRIALSAGGQRVRGEAVVTAEGIEGGAVYALSRALREAILATGAARLTVDLRPDLEADLLARRLASARPGQSRATTLRKAGSLSPVAAGLLREAAGRDLPAAPDALARLVKAAPLTLTGLQPLARAISSAGGVALGAIDARFMLTGRPGTFLAGEMLDWEAPTGGYLLQASFATGRAAAEGVLAWLARR
>NC_010511.1|WP_012334104.1|4818691_4819717_+|TerC-family-protein
MVELLSVAWLGKPIWMWLLFHAVIVLLLAFDLGLLHRDSNREIGVKESLLLTAFYLSLGLLFGGWIWWYLGPQAGQEYIAGLVVEKSLSMDNVFVIAVIFGFLGIPRVAQHRVLLWGILAAVLLRGLMIGLGAALVHEAEWVLTFFAAFLIYAGARMLFSGAEEDDEGETANRFAAFMRCRFRVTPDLHGHRFTVRLPDPKTGRMVRWFTPLALALVLVNGADVIFAVDSVPAIFAITTDTYVVYTSNIFAILGLRALYFALAAMVDRFAYLKTALALILIFIGTKIVVADTFGWIDIEPWVSLVVTVSLLAVGIAYSLWRTREAPHPIVEEPVERRAVRG
>NC_010511.1|WP_012334105.1|4820091_4821285_-|aminotransferase-class-V-fold-PLP-dependent-enzyme
MSHQPGRHFLQIPGPTNVPLPILAATARPVIDHRSAEFGQLGREVLAGIKTIFKTENPVLIYAASGTGGWESALVNTLQAGDRVLMYETGHFAALWERMARKLSLKPEFIRGDWRSGVDVAAIEAHLAGDRQHGIKAVCIVHNETATGTLSDVQGVRAALDRTGHPALLMVDTISSLGSTDYRHDAWGVDVTVGGSQKGLMLPPGLAFNAVSDKALAASRQATLPRAYWDWEDMLAANRTGYFPQTPAINLLYGLKVAIETLHAEGLDAVFARHARAAAATRAAVRHWGFETQCAVPAQASPTVTTVRMPEGHSADAFRALVLERFNMALGSGLGPLADRVFRIGHIGDFNDLTIAGALAGVEMGLAAAGIPHRAGGAAVAQAILGGKVEAFREAAE

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Crispr_ID: NC_010511_30

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_010511_30

4878890-4879137

Orphan

Consensus_repeat	Method
GTGCCGTCAGTGTCCGGGTCCGCCGCCTT	CRISPRCasFinder

3 spacers

The CRISPR arrays of NC_010511_30

>merge|NC_010511|30|4878890-4879137|CRISPRCasFinder
GTGCCGTCAGTGTCCGGGTCCGCCGCCTTGAAGCGCGCCTCGACCAGGGCGAGGTACTCGTCCTTGGTGAGGGTGCCGTCATTGTCCGGGTCCGCCGCCTTCAGCTCCTTGCGGCTCAGCCGGCCCTTCAGCTCCGTGGCGTCGACCGTGCCGTCATTGTCCTTCTCGGCCGCCTCGAAGACCTTGGTGGCGGCCGCCTTGGCTTCGGTCAGGTCGATCGTGCCGTCCGAATCCGTGTCGACCGCCGT

>NC_010511|30|30|4878890-4879137|CRISPRCasFinder
GTGCCGTCAGTGTCCGGGTCCGCCGCCTT	GAAGCGCGCCTCGACCAGGGCGAGGTACTCGTCCTTGGTGAGG
GTGCCGTCATTGTCCGGGTCCGCCGCCTT	CAGCTCCTTGCGGCTCAGCCGGCCCTTCAGCTCCGTGGCGTCGACC
GTGCCGTCATTGTCCTTCTCGGCCGCCTC	GAAGACCTTGGTGGCGGCCGCCTTGGCTTCGGTCAGGTCGATC
GTGCCGTCCGAATCCGTGTCGACCGCCGT

Protein	Signature genes	Signature genes Name	Protein_function
NC_010511.1\|WP_012334154.1\|4877235_4878381_-\|adenylate/guanylate-cyclase-domain-containing-protein	unknown	unknown	gnl\|CDD\|143636
NC_010511.1\|WP_012334150.1\|4872824_4873736_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|379164
NC_010511.1\|WP_012334162.1\|4884701_4886684_-\|heme-lyase-CcmF/NrfE-family-subunit	unknown	unknown	gnl\|CDD\|224061
NC_010511.1\|WP_012334166.1\|4890450_4891923_-\|sensor-histidine-kinase	unknown	unknown	gnl\|CDD\|223715
NC_010511.1\|WP_012334151.1\|4874365_4875115_-\|restriction-endonuclease	unknown	unknown	gnl\|CDD\|377369
NC_010511.1\|WP_012334149.1\|4871292_4872783_+\|efflux-transporter-outer-membrane-subunit	unknown	unknown	gnl\|CDD\|273830
NC_010511.1\|WP_012334161.1\|4884238_4884697_-\|cytochrome-c-type-biogenesis-protein-CcmH	unknown	unknown	gnl\|CDD\|377161
NC_010511.1\|WP_012334148.1\|4868014_4871296_+\|nodulation-protein	unknown	unknown	gnl\|CDD\|182589
NC_010511.1\|WP_012334164.1\|4887418_4888681_-\|c-type-cytochrome-biogenesis-protein-CcmI	unknown	unknown	gnl\|CDD\|226687
NC_010511.1\|WP_012334163.1\|4886810_4887302_-\|cytochrome-c-maturation-protein-CcmE	unknown	unknown	gnl\|CDD\|237317
NC_010511.1\|WP_012334155.1\|4878538_4878772_+\|hypothetical-protein	unknown	unknown	unknown
NC_010511.1\|WP_012334159.1\|4881718_4882870_+\|GGDEF-domain-containing-protein	unknown	unknown	gnl\|CDD\|143635
NC_010511.1\|WP_012334157.1\|4879359_4880682_-\|HlyC/CorC-family-transporter	unknown	unknown	gnl\|CDD\|224173
NC_010511.1\|WP_012334165.1\|4888888_4890115_+\|MFS-transporter	unknown	unknown	gnl\|CDD\|225371
NC_010511.1\|WP_012334152.1\|4875315_4876098_+\|DUF1194-domain-containing-protein	unknown	unknown	gnl\|CDD\|369046
NC_010511.1\|WP_012334158.1\|4880782_4881388_-\|pilus-biosynthesis-protein-PilZ	unknown	unknown	gnl\|CDD\|274400
NC_010511.1\|WP_012334153.1\|4876129_4876567_-\|MucR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|227293
NC_010511.1\|WP_012334160.1\|4883100_4884255_+\|GGDEF-domain-containing-protein	unknown	unknown	gnl\|CDD\|143635
NC_010511.1\|WP_012334147.1\|4864749_4867869_+\|multidrug-efflux-RND-transporter-permease-subunit	unknown	unknown	gnl\|CDD\|182501
NC_010511.1\|WP_012334146.1\|4863362_4864739_+\|MdtA/MuxA-family-multidrug-efflux-RND-transporter-periplasmic-adaptor-subunit	unknown	unknown	gnl\|CDD\|183194

Protein	Function_ID	Function_description	E-value
NC_010511.1\|WP_012334154.1\|4877235_4878381_-\|adenylate/guanylate-cyclase-domain-containing-protein	gnl\|CDD\|143636	cd07302, CHD, cyclase homology domain. Catalytic domains of the mononucleotidyl cyclases (MNC's), also called cyclase homology domains (CHDs), are part of the class III nucleotidyl cyclases. This class includes eukaryotic and prokaryotic adenylate cyclases (AC's) and guanylate cyclases (GC's). They seem to share a common catalytic mechanism in their requirement for two magnesium ions to bind the polyphosphate moiety of the nucleotide.	4.18669e-34
NC_010511.1\|WP_012334150.1\|4872824_4873736_-\|hypothetical-protein	gnl\|CDD\|379164	pfam13400, Tad, Putative Flp pilus-assembly TadE/G-like. This is an N-terminal domain on a family of putative Flp pilus-assembly proteins. The exact function is not known. The Flp-pilus biogenesis genes include the Tad genes, and some members of this family are putatively assigned as being TadG.	1.19009e-05
NC_010511.1\|WP_012334163.1\|4886810_4887302_-\|cytochrome-c-maturation-protein-CcmE	gnl\|CDD\|237317	PRK13254, PRK13254, cytochrome c maturation protein CcmE.	4.33723e-80
NC_010511.1\|WP_012334166.1\|4890450_4891923_-\|sensor-histidine-kinase	gnl\|CDD\|223715	COG0642, BaeS, Signal transduction histidine kinase [Signal transduction mechanisms].	2.2225e-39
NC_010511.1\|WP_012334151.1\|4874365_4875115_-\|restriction-endonuclease	gnl\|CDD\|377369	pfam04471, Mrr_cat, Restriction endonuclease. Prokaryotic family found in type II restriction enzymes containing the hallmark (D/E)-(D/E)XK active site. Presence of catalytic residues implicates this region in the enzymatic cleavage of DNA.	8.01039e-22
NC_010511.1\|WP_012334158.1\|4880782_4881388_-\|pilus-biosynthesis-protein-PilZ	gnl\|CDD\|274400	TIGR03030, Cellulose_synthase_UDP-forming, cellulose synthase catalytic subunit (UDP-forming). Cellulose synthase catalyzes the beta-1,4 polymerization of glucose residues in the formation of cellulose. In bacteria, the substrate is UDP-glucose. The synthase consists of two subunits (or domains in the frequent cases where it is encoded as a single polypeptide), the catalytic domain modelled here and the regulatory domain (pfam03170). The regulatory domain binds the allosteric activator cyclic di-GMP. The protein is membrane-associated and probably assembles into multimers such that the individual cellulose strands can self-assemble into multi-strand fibrils.	0.000284014
NC_010511.1\|WP_012334161.1\|4884238_4884697_-\|cytochrome-c-type-biogenesis-protein-CcmH	gnl\|CDD\|377161	pfam03918, CcmH, Cytochrome C biogenesis protein. Members of this family include NrfF, CcmH, CycL, Ccl2.	3.19315e-63
NC_010511.1\|WP_012334148.1\|4868014_4871296_+\|nodulation-protein	gnl\|CDD\|182589	PRK10614, PRK10614, multidrug efflux system subunit MdtC; Provisional.	0
NC_010511.1\|WP_012334164.1\|4887418_4888681_-\|c-type-cytochrome-biogenesis-protein-CcmI	gnl\|CDD\|226687	COG4235, COG4235, Cytochrome c biogenesis factor [Posttranslational modification, protein turnover, chaperones].	6.46593e-47
NC_010511.1\|WP_012334159.1\|4881718_4882870_+\|GGDEF-domain-containing-protein	gnl\|CDD\|143635	cd01949, GGDEF, Diguanylate-cyclase (DGC) or GGDEF domain. Diguanylate-cyclase (DGC) or GGDEF domain: Originally named after a conserved residue pattern, and initially described as a domain of unknown function 1 (DUF1). This domain is widely present in bacteria, linked to a wide range of non-homologous domains in a variety of cell signaling proteins. The domain shows homology to the adenylyl cyclase catalytic domain. This correlates with the functional information available on two GGDEF-containing proteins, namely diguanylate cyclase and phosphodiesterase A of Acetobacter xylinum, both of which regulate the turnover of cyclic diguanosine monophosphate. Together with the EAL domain, GGDEF might be involved in regulating cell surface adhesion in bacteria.	5.81492e-55
NC_010511.1\|WP_012334157.1\|4879359_4880682_-\|HlyC/CorC-family-transporter	gnl\|CDD\|224173	COG1253, TlyC, Hemolysins and related proteins containing CBS domains [General function prediction only].	1.26382e-134
NC_010511.1\|WP_012334165.1\|4888888_4890115_+\|MFS-transporter	gnl\|CDD\|225371	COG2814, AraJ, Arabinose efflux permease [Carbohydrate transport and metabolism].	1.95487e-74
NC_010511.1\|WP_012334152.1\|4875315_4876098_+\|DUF1194-domain-containing-protein	gnl\|CDD\|369046	pfam06707, DUF1194, Protein of unknown function (DUF1194). This family consists of several hypothetical Rhizobiales specific proteins of around 270 residues in length. The function of this family is unknown.	2.67838e-95
NC_010511.1\|WP_012334162.1\|4884701_4886684_-\|heme-lyase-CcmF/NrfE-family-subunit	gnl\|CDD\|224061	COG1138, CcmF, Cytochrome c biogenesis factor [Posttranslational modification, protein turnover, chaperones].	0
NC_010511.1\|WP_012334153.1\|4876129_4876567_-\|MucR-family-transcriptional-regulator	gnl\|CDD\|227293	COG4957, COG4957, Predicted transcriptional regulator [Transcription].	1.57452e-72
NC_010511.1\|WP_012334160.1\|4883100_4884255_+\|GGDEF-domain-containing-protein	gnl\|CDD\|143635	cd01949, GGDEF, Diguanylate-cyclase (DGC) or GGDEF domain. Diguanylate-cyclase (DGC) or GGDEF domain: Originally named after a conserved residue pattern, and initially described as a domain of unknown function 1 (DUF1). This domain is widely present in bacteria, linked to a wide range of non-homologous domains in a variety of cell signaling proteins. The domain shows homology to the adenylyl cyclase catalytic domain. This correlates with the functional information available on two GGDEF-containing proteins, namely diguanylate cyclase and phosphodiesterase A of Acetobacter xylinum, both of which regulate the turnover of cyclic diguanosine monophosphate. Together with the EAL domain, GGDEF might be involved in regulating cell surface adhesion in bacteria.	2.05944e-51
NC_010511.1\|WP_012334147.1\|4864749_4867869_+\|multidrug-efflux-RND-transporter-permease-subunit	gnl\|CDD\|182501	PRK10503, PRK10503, MdtB/MuxB family multidrug efflux RND transporter permease subunit.	0
NC_010511.1\|WP_012334146.1\|4863362_4864739_+\|MdtA/MuxA-family-multidrug-efflux-RND-transporter-periplasmic-adaptor-subunit	gnl\|CDD\|183194	PRK11556, PRK11556, MdtA/MuxA family multidrug efflux RND transporter periplasmic adaptor subunit.	2.23031e-134
NC_010511.1\|WP_012334149.1\|4871292_4872783_+\|efflux-transporter-outer-membrane-subunit	gnl\|CDD\|273830	TIGR01845, Outer_membrane_protein_OprM, efflux transporter, outer membrane factor (OMF) lipoprotein, NodT family. Members of this model comprise a subfamily of the Outer Membrane Factor (TCDB 1.B.17) porins. OMF proteins operate in conjunction with a primary transporter of the RND, MFS, ABC, or PET systems, and a MFP (membrane fusion protein) to tranport substrates across membranes. The complex thus formed allows transport (export) of various solutes (heavy metal cations; drugs, oligosaccharides, proteins, etc.) across the two envelopes of the Gram-negative bacterial cell envelope in a single energy-coupled step. Current data suggest that the OMF (and not the MFP) is largely responsible for the formation of both the trans-outer membrane and trans-periplasmic channels. The roles played by the MFP have yet to be determined. [Cellular processes, Detoxification, Transport and binding proteins, Porins].	1.49811e-103

>NC_010511.1|WP_012334155.1|4878538_4878772_+|hypothetical-protein
MRIRSLCLALATALAAGPALAEDVTIIRRDPPPVERSTVIEKRSVESTGSVGGCETKTVRKENEFGDSKTVRSERCD
>NC_010511.1|WP_012334154.1|4877235_4878381_-|adenylate/guanylate-cyclase-domain-containing-protein
MTRAAPLDTPAATARRRPSQASPGLIPHHVWFWVAMLALSTGAGLVYDALFSNGIPVVAAVYGFCIGVCGLLLERGLLVPRLQARCRQLPTLLYVPLAELAYVGMIALGHGLGGLLVWGTGLSRDRFVDAVIPSPRALVYALAVSALLVFVVRMRDLIGAEVFVNLMIGRYHRPVEEERIFLFVDVVGSTAYAETRGDLKAQAYLSAVFAAVAEPVRRYQGSTDDFIGDMAMITWPMARGLQDARCVACVFAIREALTRDSAAWRERFGVVPEVRAALHGGSVVTAEVGVDRHKIAYFGDAVNVTARIETLCRTLDAPVLISADLLDLLPHLPPGVRATPLGRHTLRGRDQTLAVASLARDALPEAAAAGSGAAGRMRAAR
>NC_010511.1|WP_012334153.1|4876129_4876567_-|MucR-family-transcriptional-regulator
MSESEASTDYIELAADIVSAFVSKNSVPMADLPALIASVHETLGRLGKDPAEEKPEPLTPAVPIKKSITPDYLICLEDGKKFKSLKRHLRSRYGLTPEEYRARWNLAPDYPMVAPNYAAARSELAKTMGLGQQRRRTGGGRRDGA
>NC_010511.1|WP_012334152.1|4875315_4876098_+|DUF1194-domain-containing-protein
MRRSSLACLALLLCCAVGRSAEAPVEVDVALVLAVDVSLSMTAEEQLVQRSGYVEAFRSAVVQRAVGLGQIGRIAVTYVEWAGVGNQRVVVPWTLIGSPEEAASFAERLAQSPPRRSTWTSIASAIDFSVGLLSHGGFAPLRRVIDVSGDGPNNQGRPVTRARDDAVDRGITINGLPLMIREPSGPWDIKDLDLYYRDCVIGGPGSFMIPVREREQFAEAIRVKIVREVAERGAAAPLRRTQAASPTNCLVGDRPSPDWD
>NC_010511.1|WP_012334151.1|4874365_4875115_-|restriction-endonuclease
MAAPRSIADLAFWPVVAGTLASLWIGRAALAAGGLALAVILVRRLGRGRRFRRRARALVARHREVLALRRRQESYLDAYDNLILDGWERERAYYIARTLVPRLEAEGYADLIPERRADLVAIVEAASLAPAGPEEELPDDGIAYERYCAALLERAGWAARATRASGDQGADVIAEQRGVRLVLQCKRYTKPVGNAAVQEVVAARSYWSADWAAVVSNAGFTPAARKLAAATDVLLLHHDDLAVLELDEG
>NC_010511.1|WP_012334150.1|4872824_4873736_-|hypothetical-protein
MIEVSPVRVRRAVPGWRSDARGTIGIMFAGMMPAVLLAIGCGIDLQRALAYRGKVQAALDGAVMAVVGNTSFDADFGRQAFKTSASFAYALDGAAPGSDPLTITRLTFTQNPDGTVTAEATATMRTTVVSIIGVRSLDLSFRSTAKGTTTLKISTITFKVLSAQGAFDKDIYFFTRDGNGNLLSESLVLQYDYNYPAGGTATKSYNPPPPQTFTQPVSNYKTYGFKMVVYKDPSYRGLHVNPSVYYSDSSNSSQWIRIQGKCYDPGGSTQYWEDGGDFNYQDFVYSVTCTTTNKVDRDVRLVE
>NC_010511.1|WP_012334149.1|4871292_4872783_+|efflux-transporter-outer-membrane-subunit
MSALPARIGAAILPPLLLGGCLVGPDYARPSVETPLAYKEGGAPATAMPGRHWRPARPRDEADRGDWWRVYRDPALDRMIRLIDVDNQSLRNAVAAYRQARALVQEARAQLFPTVLGAPGISRSRSAGIERTTLTLQGSASWELDLFGRVRRQIESDVAAAQASAADIAAVRLATQAELASTYFQLRYQESLQRLLDQTVQAYQRSLAIAENQYAAGVAARSDVITAQTQLQTTQAQAIAVGLQRAIFEHAIATLIGRPPSEVSLARARLAAAPPSVPVSLPSDLLERRPDVAAAERAVQRQSEQIGVAVAAFYPTVTLSANGGIAGDPARNFFSAANTFWSVAANGSQVLFDGGARGAALQAARAAYDANVATYRQTVLTAFQEVENGLSGQRILARQAAAQNVAVESSRRAVEIALNEYRAGTQNYTTVVTAQALALSNEVTALQILLNRFTNSVSLIRALGGGWDIRALPSGDELKGFRTLPIDTGQALRPDE
>NC_010511.1|WP_012334148.1|4868014_4871296_+|nodulation-protein
MNLSRPFILRPVATTLLSIGVLLAGLFAFLRLPVAPLPQVDFPTILVQAQMAGASPETMAATVAAPLERRLGQIADVDQMTSTSSTGQTRIVLQFSLDRDINGAARDVQAAINAARADLPTALRQNPTYRKFNPADAPILIVGLTSKTLNPSSLYDSAATVVQQKLSQLEGIGNVDASGSSLPAVRVELEPGALFHYGIGLEGIRAAIASANANSPKGAIETVTRRYQLYANDQGRVAADYQDIVVAYRNGAAVRLRDVGEVVDGVEDRRNLGLVNGRPGVLLIVYKQPGGNVVETVDRLKAALPQIKAALPGDIDLVVTGDRSLTIRASLREAERTLMISVGLVILVVFVFLRSARATLIPAVAVPVSLVGTFAAMYLCNYSLDNISLMALIIAAGFVVDDAIVVLENIQRHIEEGRPRLEAALLGAREVGFTVLSMSLSLVAVFMPILLMGGLIGRFFQEFAVVLSLAILISLVLSLTTTPMMCARLLRPEPHGRRPNLLARGLEAGFDWVLRGYGRSLGFALRHGALVMLVMVGAIALNVWLFVIVPKGFFPQQDAGQMIGGIQADQRISFQAMSAKLKQATDIVQADPAVESVVGFTGGRGTNSANVFVGLKPLGTRDPIAQVMGRLRPKLAAIPGARLYLFPRQDFMVGGRQSFSQFQYTLQGDAGEELYAWAPKLVELLQKDPIFTDVTSDQQQGGLESRLVVDRATAYRYGLTPDLIDNTLYDAFGQRQVSTIYNALNQYRVVMEIAPRYLGNPETLKQIYVSTSGARARGSASTNAVAGTVQSAQIAAGDASAAAAAVATDSARNAATNAIAGKAGASSAAAVSSAKETMVPLSAFSRFESGTAPVQVSHQGLFVATTLSFNLAPGRTLGDATAAIEAHMRALRMPATIHGEFAGAAKSFQASSSRQPLLILAALLTVYAVLGILYESFVHPITILSTLPSAGIGAILALMLTGEEFGVIALIAIFLLIGIVKKNAIMMIDFALDAQRSRGVDPREAITQACLLRFRPILMTTLAALLGALPLILDGGEGSELRRPLGIAIVGGLIVSQVLTLYTTPVVYLVLDRLRLRVTRRPSGPTPLPAPAE
>NC_010511.1|WP_012334147.1|4864749_4867869_+|multidrug-efflux-RND-transporter-permease-subunit
MNPSRLFILRPVATTLLMLAILLTGLLSYLNLPLSALPSVDYPTIQVQTFYPGASPEVMTSAVTAPLERQFGQLANLNQMTSQSSAGASVITLQFNLDLSLDIATQEVQAAINAAGNLLPSDLPAPPVYAKVNPADAPILTLALTSKTLALTQVRDLAETRLAQKISQVAGVGLVTMAGGQRPAVRVRFNSRALAAYGLNIDDLRTTIANLNVNTPKGTIDGPAQSFAINANDQIRDPAVYRDAIIAYRNGAPVTLSAVADVVEGPENTKLGAWMDTTPAIILNIQRQPGANVIAVVDRIKALLPQLQATLPAAIQVTPLTDRTVTIRASVHDVQMELLLAIALVVLVIFLFLRSLPATLIPSLSVPLSLVGALAVMDLWGFSLDNLSLMALTIATGFVVDDAIVVIENIARHVEEGASPFEAALKGSEEIGFTIISLTVSLLAVLIPLLFMGEVVGRLFHEFAITLAATIVISGIVSLTLVPMLCARLLRHAPPRARREGRLARAGRWTMEAGIGLYGRTLRGVLNHQGLTLVVALGTLILTFHLYVVIPKGFFPVQDTGLIQGISQADQTVSFAAMAERQQRLAEAILKDPDVVSVSSFIGVDGQNVTLNSGRFLINLRPREARAEHAGAIIRRIAARTAEVPGTTLYMQPVQDLTIDTAVSPTQYQFILENPDLNAFEAWVPRFVERLRRIPDLADVASDRQANGLAAHITIDRATAGRYGITPASVDNALYDAFGQRIISTIFTQSNQYRVILEADPDLHRTLASLNRIYLPSSTAQNGQVPLSAIATVTEKRAPLLISHLGQFPATTISFNLAPGASLGPAVAAIEAARAEIGLPDSFQLVFQGSALAFQSSLKNTLFLVLAAIVTVYIVLGVLYESFIHPITILSTLPSAGIGALAGLMLFGLDLDIIGIIGIVLLIGIVKKNAIMMIDFALQAEREEGKSPRDAIYEACLLRFRPIMMTTFAALFAAVPMIFGSGTGAELRQPLGISIAGGLIVSQVLTLYTTPVIYLAFDRLARRLGGRRRGGLAPGGAVP
>NC_010511.1|WP_012334146.1|4863362_4864739_+|MdtA/MuxA-family-multidrug-efflux-RND-transporter-periplasmic-adaptor-subunit
MNELSPIRTDDAVEAGSRRRRRWPFWLLVLLALAGGGVWAFRDSLPNGFQFQVKQAAKPEMGRRGGRRFAGGDGPQAVGVATVVTGEMPVVLSGLGTVTPLATVTVRSQVSGYLTRIGFREGQHVREGDFLAQIDVRPYEALLAQYQGQLQRDQALLQNARLDLTRYQTLNRQDSISKQNVDTQAATVKQYEGVVASDQAQIDQQKLNIQYGRITAPVDGRVGLRQIDQGNYVTAASTSIVVVTQLQPISVLFTLPEDVLARVMARLRGGAKLPVRIFDRSDTAEIASGMLDTVDNQIDVTTGTVKLRALFPNADDRLFPNQFVNAKLLVDTVRDAPVIPAAAVLRGTPGTFVYLLGEDGKVSVRPITVGETDGNRTVVTSGLKPGDQVVVDGTDRLRDGAEVKVAARAAPEARAGGAEPAARPAAEPAAGEARPRAEAEAPPAEGERPHRRRRPPTP
>NC_010511.1|WP_012334157.1|4879359_4880682_-|HlyC/CorC-family-transporter
MIFSDSAWGTGLGLFAVVFLVFANGFFVAAEFALVAVRRSRVQELVAERRANAAALQRATDHLDAHLAATQLGITISSLALGWVGEPALAHLIEPLLAWLPSPLGIASAHAIAVAIAFVVITALHIVLGELAPKSLALQRSERTALVVVRPLRLFLILFRPAIAFLNGLGNGVLRLCGLQPGTGEDSLHSPAELTLLVAASQEAGLIQEAQQEAVARIFGIGERRIRDIMTPRHEVDWVDVEEPREAILDSVRACRHEALVASRGEIHEIVGVLRKQDILNQILDGAEPDIAGLVREPIVVHEAMPILRVLETFKAKPVRMAIVVDEYGNLEGIVTQTDLLEAIAGDIPDAEDEEPMVVERQDGSLLIDGMMPAVEAFERLGFSQAPDTDEYSTLAGYVISELGRIPTAGDTFEREGWRFEVVDMDGRRVDKVLAERPSP
>NC_010511.1|WP_012334158.1|4880782_4881388_-|pilus-biosynthesis-protein-PilZ
MVQTSERVSSPDSRRAGPAPVLLRIAGRYLLPNGDEHACETRSLSPAEADLLAAVPGLLGDPVTIYLDTIGAITGVIRSLTPTGFVVAIEVSPERRARIAARLDWLAARANGRIDQRSDARIVPVTKAVEVKLPDGALLPGTLIDLSMSGAAVAMAARPAVGATVTVGKRFATVVRHLDGGIAVAFKLPFRPETFNDQVVL
>NC_010511.1|WP_012334159.1|4881718_4882870_+|GGDEF-domain-containing-protein
MLDVATLLAVATCLCFIVGLLFLLSWRQAPRTRALAIWGVGHLLAAVASVLLAGQGTLPDLVSIGLANALMLGAFGLMWSGARSFEGRRTPLAALAAAPALWCAACAVPAFLASSSGRVMLVAALAAVPCGLTAREIWRGRGEPLVSRLPAAALTASEALLFVVRIPLTALRPPSEPYPLTLPGMGALVLLGLLYTVALAFLFLALAKERLEWQQRLSALTDPLTGALNRRGLEQAAACVLAGGPATLLLLDLDHFKRVNDTYGHGVGDEVLVACAAAMPGCLPPRAVIGRLGGEEFACLLPDGEGAGEIAEAIRRAVAALRLERAPDLHVTASIGAARGGSELQCLIARADRALYRAKRGGRNRVAWDPDRVGPPPDLDLAS
>NC_010511.1|WP_012334160.1|4883100_4884255_+|GGDEF-domain-containing-protein
MVLDAATLMLVTMFVTLIVGLLFLLSWRQARQTRALAIWGFAHLLGAAGSALISGRGLIPDALSVGLANAIMLGAYALIWSGARSFEGRGTSPAALLAAPLLWLAACAVPDFYASMTARIVGASGAAALLCGLTAWEIWRGRDEPLVSRAPAAAVVGSEALLYAVRIPATLTFPVPAGNPLVSPWVAVLCFAALLYTVAIAFLFMALAKERLEWEQRLSALSDPLTGVCNRRGLEVRAASLLASGRATLLLFDLDHFKRVNDTYGHAIGDAVLVGFCAAAQALLPPQAVLARLGGEEFACLLPADAAAGPIAETIRRAVAALRPDCEPGLRITVSVGAARGGTSLERLLARADAALYEAKRLGRDRVVWAAGARRGDRALSAAS
>NC_010511.1|WP_012334161.1|4884238_4884697_-|cytochrome-c-type-biogenesis-protein-CcmH
MPRLLPVALLLLLAFAPAARAVQPNEVMADPQLEARARDISAGLRCLVCQNQSIDDSDAPLARDLRLIVRERLRQGDDDQAVVDYVVRRYGEFVLLRPVLAWHTAVLWLTPPAVLALGGLGLWLRARRRRPARPASLSPEEEAALAELTRPR
>NC_010511.1|WP_012334162.1|4884701_4886684_-|heme-lyase-CcmF/NrfE-family-subunit
MLIEAGHYALALALALSLAQAVMPAWAARARDPILRSVAVPAALATFACIAFAFAALTLAHVRSDFSVLNVFENSHSLKPLVYKISGVWGNHEGSMLLWVLILALFGAIVALARDSVPAALRANTLGVQATVTFVFLLFILTTSNPFARLDPAPAEGRDLNPILQDPGLAIHPPLLYLGYVGFSITFAFAIAALLEGRIDAVWARAVRPWTLLAWCFLTVGIAMGSYWAYYELGWGGWWFWDPVENASLMPWLAGTALIHSTVVMEKRDALKVWTVLLAILTFSLSLLGTFLVRSGVLTSVHTFATDPARGTFILAILVLFIGGSLALFAWRAPLLRQGGIFAPISREGALVLNNLFLSAACATVLVGTLYPLVLESLTGEKISVGAPFFNLTFLPLAVPLLLLVPFGQTLAWKRGDLGAAAQRLLIGVGAGIAATLGMIALRRGGPAAAPLGIGLGAYLVVGAAMEIATRAKGRSLGLSLRRAAGLPRSAWGTAMAHAGVGLTVIGIAAQAWSVEALATVPRGGQLTAGPYTATLSGIVPRTGPNYTETVAQLAIRGPDGALVGTLDPGKRFFGARNMAVSEASLLTIGVSQVYASVGESQADGALGIRLYYKPLVLLIWLGAVVMALGGGLSLTDRRFRIGAPAQRRVPAESAPVPAE
>NC_010511.1|WP_012334163.1|4886810_4887302_-|cytochrome-c-maturation-protein-CcmE
MTRKQRRLVFIGTCGAVLAVALGLVLWAMSGTIVFFRSPSEIAREAVAPGVRFRLGGLVEAGSVVRGPDSQVTFAVTDNAARLPVRYRGLLPDLFREGQGVVAEGAMEPGGVFRADTVLAKHDETYMPREVADALKKSGRWQEGAGHPAPAPPRTASGEARAP
>NC_010511.1|WP_012334164.1|4887418_4888681_-|c-type-cytochrome-biogenesis-protein-CcmI
MTAIWFLFAAMTGAAVLALLWPLSRRPNPALPEAGAESLLATETGFYEDQLRDIERDRARGLIGPGEAEAARAEAARRLLRASRTLGTADAPRVGEPALRHRRAASAFALSTVPLVALIVYGLYGAPSLPSQPQAERLAAARDSARDPAGRDSATRDSATRDLASGIAQIETHLAKHPEDGRGWEVLAPVYLRLGRTEDAVRAYESALRLLGDSGTRLADYGEALVASADGMVSGQARGAFERSLAADPSGVKPRFYLARAAEQDGDRALALSRYAALAEASPADAPWMPLLRESIQRLGGTPPAGGPRPESGARPEGEAKPEGGAKPALPGSGGTPPGEAGPGLSEEQRGAIRGMVAGLDRRLAAQGGSPEEWARLVRSYGVMGERDRAAEALARARAALGGEAGPVEAVARELGLAAP
>NC_010511.1|WP_012334165.1|4888888_4890115_+|MFS-transporter
MPSAFPDPARPAAADPRARRPGLALLALATGGFAIGTTEFAAMSLVPDFAPDLGIDAPTAGHVISAYALGVVVGAPVIAVLAARIARRTLLIGLMLLFALGNGLSALAPGYPSMLACRFLAGLPHGAYFGVAALVAASLVAPARRAQAVARVLAGLTVATIVGVPLANLVGLWIGWRWSFALVAGLALLTALLVRLLAPLGPAAPGASALRELGALRRGQVWLTLATGAIGFGGLFAVYTYLASTLLGVARAAPGTVPVLLGLFGLGLTIGNLVCAWAADRFQMPAAGATLVWSAAALALYPAATASLWTLAPVVFLIGCGGGLSTILQTRLMDVAQDAQTLAAALNHSAFNVANALGPWLAGLVLARGFGLPATGYVGAALALGGLAIWAVSLAAERGEARGLQAAE
>NC_010511.1|WP_012334166.1|4890450_4891923_-|sensor-histidine-kinase
MNAPARGVAGSVGPETEAAAPARAPAWRPWRRRSIAVRLAVSALLSSALILLIAGLILSTLYRETTERAFDSRLIVYANDLATNLVSPGDSEGRALGTLGDPRFDLPLSGWYWQVGRPNAKPRDIRTSRSLVGVPLPPPDNAVGEAGAGQLRKGYGRAQDERPLRIIERTVDLGEEGRYVVRVAGPSDEIESDMRRFSMALVTTFSMLGLSLGLTTLLQIRFGLAPLTKLRAALGAIRRGEADRISGDYPHDIAPLAGEVNLLIETNREILERARTQVGNLAHALKTPLSIIVNEAEAVDASSELAGKIREQAAIMRDQVNYHLDRARAAALAGTLGTFTDVEPVVAALIRTFGKIYRDKTLAFDAAITPGLRFRGERQDLEEMIGNLVDNASKWAAGRVAIRAEVIGQGEYPHLIVTVEDDGPGLPPEARVAVLKRGRRLDETKPGSGLGLSIVADLATLYRGRLRLEAASLGGLRAVVEIPGDASPKA

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Crispr_ID: NC_010511_31

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_010511_31

4920618-4920708

Orphan

Consensus_repeat	Method
CGACATCCGGTTGATCGCTTCGC	CRISPRCasFinder

1 spacers

The CRISPR arrays of NC_010511_31

>merge|NC_010511|31|4920618-4920708|CRISPRCasFinder
CGACATCCGGTTGATCGCTTCGCGATGTGGATGTCGGCTTCGCTCAGGCGCCGCGCGGGCTTGGCATACGACATCCGGTTGATCGCTTCGC

>NC_010511|31|31|4920618-4920708|CRISPRCasFinder
CGACATCCGGTTGATCGCTTCGC	GATGTGGATGTCGGCTTCGCTCAGGCGCCGCGCGGGCTTGGCATA
CGACATCCGGTTGATCGCTTCGC

Protein	Signature genes	Signature genes Name	Protein_function
NC_010511.1\|WP_012334201.1\|4922397_4923099_+\|oxidoreductase	unknown	unknown	gnl\|CDD\|99813
NC_010511.1\|WP_012334193.1\|4915801_4916470_-\|LON-peptidase-substrate-binding-domain-containing-protein	unknown	unknown	gnl\|CDD\|225362
NC_010511.1\|WP_012334203.1\|4924643_4925426_-\|DUF4198-domain-containing-protein	unknown	unknown	gnl\|CDD\|378467
NC_010511.1\|WP_012334192.1\|4915214_4915676_+\|peptidylprolyl-isomerase	unknown	unknown	gnl\|CDD\|223725
NC_010511.1\|WP_012334189.1\|4913605_4914106_+\|pantetheine-phosphate-adenylyltransferase	unknown	unknown	gnl\|CDD\|234674
NC_010511.1\|WP_012334194.1\|4916536_4917445_-\|thioredoxin	unknown	unknown	gnl\|CDD\|225660
NC_010511.1\|WP_012334199.1\|4921535_4921709_+\|hypothetical-protein	unknown	unknown	unknown
NC_010511.1\|WP_012334196.1\|4919583_4920567_+\|cysteine-synthase-A	unknown	unknown	gnl\|CDD\|273463
NC_010511.1\|WP_012334198.1\|4921332_4921539_+\|hypothetical-protein	unknown	unknown	unknown
NC_010511.1\|WP_012334204.1\|4925870_4927067_+\|helix-turn-helix-transcriptional-regulator	unknown	unknown	gnl\|CDD\|197715
NC_010511.1\|WP_012334200.1\|4921790_4922396_+\|sulfite-oxidase-like-oxidoreductase	unknown	unknown	gnl\|CDD\|239027
NC_010511.1\|WP_012334197.1\|4920813_4921107_-\|hypothetical-protein	unknown	unknown	unknown
NC_010511.1\|WP_012334191.1\|4914736_4915222_+\|hypothetical-protein	unknown	unknown	unknown
NC_010511.1\|WP_012334190.1\|4914207_4914747_+\|peptidylprolyl-isomerase	unknown	unknown	gnl\|CDD\|223725
NC_010511.1\|WP_012334205.1\|4927289_4928546_-\|CCA-tRNA-nucleotidyltransferase	unknown	unknown	gnl\|CDD\|223690
NC_010511.1\|WP_012334202.1\|4923192_4924587_+\|FAD-binding-oxidoreductase	unknown	unknown	gnl\|CDD\|223354
NC_010511.1\|WP_012334195.1\|4917685_4919443_+\|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|224055
NC_010511.1\|WP_012334188.1\|4912821_4913562_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|226222
NC_010511.1\|WP_012334206.1\|4928542_4928800_-\|hypothetical-protein	unknown	unknown	unknown
NC_010511.1\|WP_043701492.1\|4912125_4912695_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|240291

Protein	Function_ID	Function_description	E-value
NC_010511.1\|WP_012334193.1\|4915801_4916470_-\|LON-peptidase-substrate-binding-domain-containing-protein	gnl\|CDD\|225362	COG2802, COG2802, Uncharacterized protein, similar to the N-terminal domain of Lon protease [General function prediction only].	2.16404e-67
NC_010511.1\|WP_012334192.1\|4915214_4915676_+\|peptidylprolyl-isomerase	gnl\|CDD\|223725	COG0652, PpiB, Peptidyl-prolyl cis-trans isomerase (rotamase) - cyclophilin family [Posttranslational modification, protein turnover, chaperones].	2.62739e-70
NC_010511.1\|WP_012334194.1\|4916536_4917445_-\|thioredoxin	gnl\|CDD\|225660	COG3118, COG3118, Thioredoxin domain-containing protein [Posttranslational modification, protein turnover, chaperones].	1.06372e-105
NC_010511.1\|WP_012334201.1\|4922397_4923099_+\|oxidoreductase	gnl\|CDD\|99813	cd06217, FNR_iron_sulfur_binding_3, Iron-sulfur binding ferredoxin reductase (FNR) proteins combine the FAD and NAD(P) binding regions of FNR with an iron-sulfur binding cluster domain. Ferredoxin-NADP+ (oxido)reductase is an FAD-containing enzyme that catalyzes the reversible electron transfer between NADP(H) and electron carrier proteins such as ferredoxin and flavodoxin. Isoforms of these flavoproteins (i.e. having a non-covalently bound FAD as a prosthetic group) are present in chloroplasts, mitochondria, and bacteria in which they participate in a wide variety of redox metabolic pathways. The C-terminal domain contains most of the NADP(H) binding residues and the N-terminal domain interacts non-covalently with the isoalloxazine rings of the flavin molecule which lies largely in a large gap between the two domains. Ferredoxin-NADP+ reductase first accepts one electron from reduced ferredoxin to form a flavin semiquinone intermediate. The enzyme then accepts a second electron to form FADH2 which then transfers two electrons and a proton to NADP+ to form NADPH.	1.0788e-89
NC_010511.1\|WP_012334189.1\|4913605_4914106_+\|pantetheine-phosphate-adenylyltransferase	gnl\|CDD\|234674	PRK00168, coaD, phosphopantetheine adenylyltransferase; Provisional.	3.80001e-82
NC_010511.1\|WP_012334196.1\|4919583_4920567_+\|cysteine-synthase-A	gnl\|CDD\|273463	TIGR01136, Cysteine_synthase, cysteine synthase. This model discriminates cysteine synthases (EC 2.5.1.47) (both CysK and CysM) from cystathionine beta-synthase, a protein found primarily in eukaryotes and carrying a C-terminal CBS domain lacking from this protein. Bacterial proteins lacking the CBS domain but otherwise showing resemblamnce to cystathionine beta-synthases and considerable phylogenetic distance from known cysteine synthases were excluded from the seed and score below the trusted cutoff. [Amino acid biosynthesis, Serine family].	2.56604e-170
NC_010511.1\|WP_012334204.1\|4925870_4927067_+\|helix-turn-helix-transcriptional-regulator	gnl\|CDD\|197715	smart00421, HTH_LUXR, helix_turn_helix, Lux Regulon. lux regulon (activates the bioluminescence operon.	2.27213e-10
NC_010511.1\|WP_012334200.1\|4921790_4922396_+\|sulfite-oxidase-like-oxidoreductase	gnl\|CDD\|239027	cd02109, arch_bact_SO_family_Moco, bacterial and archael members of the sulfite oxidase (SO) family of molybdopterin binding domains. This molybdopterin cofactor (Moco) binding domain is found in a variety of oxidoreductases, main members of this family are nitrate reductase (NR) and sulfite oxidase (SO). Common features of all known members of this family are that they contain one single pterin cofactor and part of the coordination of the metal (Mo) is a cysteine ligand of the protein and that they catalyze the transfer of an oxygen to or from a lone pair of electrons on the substrate. The specific function of this subgroup is unknown.	2.76635e-93
NC_010511.1\|WP_012334203.1\|4924643_4925426_-\|DUF4198-domain-containing-protein	gnl\|CDD\|378467	pfam10670, DUF4198, Domain of unknown function (DUF4198). This family was previously missannotated in Pfam as NikM.	3.5947e-25
NC_010511.1\|WP_012334190.1\|4914207_4914747_+\|peptidylprolyl-isomerase	gnl\|CDD\|223725	COG0652, PpiB, Peptidyl-prolyl cis-trans isomerase (rotamase) - cyclophilin family [Posttranslational modification, protein turnover, chaperones].	1.36557e-64
NC_010511.1\|WP_012334205.1\|4927289_4928546_-\|CCA-tRNA-nucleotidyltransferase	gnl\|CDD\|223690	COG0617, PcnB, tRNA nucleotidyltransferase/poly(A) polymerase [Translation, ribosomal structure and biogenesis].	4.76216e-65
NC_010511.1\|WP_012334202.1\|4923192_4924587_+\|FAD-binding-oxidoreductase	gnl\|CDD\|223354	COG0277, GlcD, FAD/FMN-containing dehydrogenases [Energy production and conversion].	7.65406e-109
NC_010511.1\|WP_012334195.1\|4917685_4919443_+\|ABC-transporter-ATP-binding-protein	gnl\|CDD\|224055	COG1132, MdlB, ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms].	1.67235e-92
NC_010511.1\|WP_012334188.1\|4912821_4913562_+\|hypothetical-protein	gnl\|CDD\|226222	COG3698, COG3698, Predicted periplasmic protein [Function unknown].	4.37925e-96
NC_010511.1\|WP_043701492.1\|4912125_4912695_-\|hypothetical-protein	gnl\|CDD\|240291	PTZ00146, PTZ00146, fibrillarin; Provisional.	1.26381e-07

>NC_010511.1|WP_012334196.1|4919583_4920567_+|cysteine-synthase-A
MADAAITASDTGRAPGHGRVFGSITETIGNTPLVRLNRLPRERGVEAEILLKLEFFNPIASVKDRIGVNMIDALEASGDLKPGGTLVEPTSGNTGIALAFVAAARGYRLILVMPETMSLERRKMLAFLGAELVLTPGPQGMKGAVAKAEELLREIPGSVMPQQFNNPANPEIHRKTTAEEIWNDTQGRLDVFVSGVGTGGTITGVGQVLKPRLPQLRLVAVEPEDSPVLSGGNPGPHKIQGIGAGFVPNVLDRDVIDEVVTVSNQTAFETARLLGRLEGIPGGISTGANVAAALEIGARPENRGKRIVTVACSFAERYISSALFDGI
>NC_010511.1|WP_012334195.1|4917685_4919443_+|ABC-transporter-ATP-binding-protein
MRALIDLLRVMRPPERRRITLLALGLAASGLLEIAGVASVVPFLTLVGDPGAASRQPVVAALRATLGLTDDRAFLMATGLSALGAILTVSVVNAGLTYAQLLFAHLTGYGLARRLLARYVTRDRLFFARTNSAELAKNVLSETDRLVIGVLTPGFVIASRAVSAGAVALFLLLYAPALALILGAGFGSLYVGLYLLVRARLARIGARATADNETRFRVVQETFGALTELSLYGRVGSFTARFDAPARAYARASAASLVTGQLPRYVIEALAFGGVIVVVLYALARGLDTAALLPLLGLFAFAGYRMLPAFQNIFNSLAQLRFYLPALGRIVDELAREHPLPPRPAERLPFREAIRFEGVSFAYEPGRPVLRGLDLAIAAHTTVGLVGRTGSGKSTLVGLLLGLVVPGEGAIRIDGVPLDAARLPAWQNRIGYVPQDVFLIDGTVAENIALGVAAPDPAAIARAARLAGLDPVVAALPAGFETAVGERGARLSGGQRQRIGIARALYHDPDVIVFDEATSALDGETEAAVMAAIAALAGTRTIVMVAHRLTSLARANVVHVLEDGRVAESGPPETVLPRLGRLKPA
>NC_010511.1|WP_012334194.1|4916536_4917445_-|thioredoxin
MLTDTPAAGQAPADALIKDTTTNAFRQDVMQESLRQPVLVDFWAPWCGPCKQLTPILEKAVKNAGGKVKLVKMNIDEHPQIAGQLGIQSIPAVIAFQRGQPVDGFMGALPEGQVKAFIERLVGPLGPTDVEALMAEAEAVAQEGDSDAAAEIYSAVLAQEPGHAGAIAALAKLVLDRGDVEGARQFLDAAPPEAAKSAAVASVRAAIDLAEQAASLGDLGALQRQVESEPSDHQARFDLALGLNARGRQEDAVNHLIEIVRRDRGWNEDAARKQLLQFFEAWGPMDPMTIRGRRKLSSLMFS
>NC_010511.1|WP_012334193.1|4915801_4916470_-|LON-peptidase-substrate-binding-domain-containing-protein
MSMNVAYKGPGDCPTVIPVFPLPGALLLPRGQMPLNIFEPRYLAMVDDALRSDRVIGMIQPDVDASEQPLAPKLYRVGCAGRITQFAETGDGRYLISLTGIARFRVEEEMATTTPYRLCRVSFDPFTADFHARAGEERVDRAGVLRALKDFVEANDLKVDWAGIEEAPNEALVNALCMMSPFGPREKQAMLEAPDLKTRAEVLIAVTEMELVRGSGSEPTLQ
>NC_010511.1|WP_012334192.1|4915214_4915676_+|peptidylprolyl-isomerase
MSDQNTLVMETTKGRVVIQLRPDLAPNHVERIRTLAEQGFYDGVPFHRVIDGFMAQTGDPTGTGTGGSDLPDLKAEFNAEPHVRGTCSMARTSFPHSANSQFFICFADAPFLNRQYTVWGKVTEGMEVVDQIKRGEPVRDPDKIVSMRVKQAA
>NC_010511.1|WP_012334191.1|4914736_4915222_+|hypothetical-protein
MVSSGPGPAGLIAAAAALALAAGPAAAQFEDDEAPLLPSLPTTLRATVRVPVDRAALVSPADTLVQLYPALAACWDPPPGLGRGQVTLRLSLTRDGRLAGVPRVTFASLPPERRRPLVEAAQRAVRACTPVALTAALGGAVAGRPIALRFVYSGEKETRHE
>NC_010511.1|WP_012334190.1|4914207_4914747_+|peptidylprolyl-isomerase
MIRWLVALAFTVAASFGAAAAPDANTVYLDTKDGRITIQLRPELAPKHAQQIKTLVRQGFYNGVPFHRVIDGFMAQTGDPTGTGTGKSKLPDLPAEFTPTPFKRGTVGMARSQDPNSANSQFFICFDEAPFLNNQYTVVGTVTAGMDVVDKIKKGAKSANGQVQNPDKIVRMTLAQDGQ
>NC_010511.1|WP_012334189.1|4913605_4914106_+|pantetheine-phosphate-adenylyltransferase
MNRTALYAGSFDPVTNGHVDVIRQACRLVPRLVIAIGVHPGKTPLFGAEERAELLREICAPLAAAEGAALDVVTFDDLAVSAARRVGASLFIRGLRDGTDLDYEMQLAGMNGAMAPEVQTVFLPASTGVRPITATLVRQIAAMGGDVRPFVPDLVAERLRARFAKP
>NC_010511.1|WP_012334188.1|4912821_4913562_+|hypothetical-protein
MLGWGGARAWTAGALLLWAVAARAAEPCVPVSHEGERFVACTVDLRRSRIKLFWRGADGQPYASLGRLAAAQGKGLSFAMNAGMYDAGLAPVGLYVEEGRELKAANTANGPGNFHLKPNGVFYVSGDRAGVLETGRYLRARVRAEYATQSGPMLVLAGRIHPKISTNGPSLKIRNGVGVRPDGHVAVFAISEAPVTFGAFARLFRDALGCPNALFLDGSVSSLYAPALNRQDLSRPLGPLVGAVPR
>NC_010511.1|WP_043701492.1|4912125_4912695_-|hypothetical-protein
MTRVMVASAALVGALMLAPTMAEARGGFGGGGFHGGGGGFRGGLGGGGFRGGLGGGGFRGGFAGGGFRGAGFGGGFRNAGFGAGLGRPAFGGGYGFRGARFGYGGYGYRGYGYRGYGYRRGYGYGAAGLGLGLGLGLAAASAYPYYYGGYYPASYYGYGYDDYGGCYQVPRVRWTPYGYRRVLVTRCDY
>NC_010511.1|WP_012334197.1|4920813_4921107_-|hypothetical-protein
MVMPNRLVKSAWIAAEVTRETAEKVLVVEAYIAVSPLESGYDPARYGQLVEDVRRILAENPDIDRASILSVHRESRCAALFRRSVPDCTAGKPELVA
>NC_010511.1|WP_012334198.1|4921332_4921539_+|hypothetical-protein
MGPGMTRTDGTDRDFDRESDRAGAAGRDRQPPRGRPEGAGRPADAPPPAAKEAIARATAALGDEEDGR
>NC_010511.1|WP_012334199.1|4921535_4921709_+|hypothetical-protein
MSDETREQARPARTDRPVTAEDLKGVAAVPQDGKGAENRSGADASDRQGDETDPGTG
>NC_010511.1|WP_012334200.1|4921790_4922396_+|sulfite-oxidase-like-oxidoreductase
MATRGFTGRRPSRPVEERLPPGQYLTEDFPVLQLGPTPRIALRDWRFTLWQGPRPLKSWTWEEFQTLPRSGWRGDIHCVTKWSKFDTGWEGVRVDDLLTAAGIAAPTAFVLAEGYDDYTTNVPFADLAGDRAMVATHYDGAPIAPDHGGPARLLVPHLYFWKSAKWVKGLRFTPKDEAGFWELRGYHMYGDPWREQRFSDD
>NC_010511.1|WP_012334201.1|4922397_4923099_+|oxidoreductase
MVLAWQEAVITGIAAETPRVKRFTLRPDRPFAFRAGQHVDVRLTAPDGYQAQRSYSIASAPGSDAFDLMIERLDAGEVSTFFADVAEAGDRIELRGPIGAFAWGAGEGGPLLLVGGGSGVVPLLSMLRHRAAAAPGVPALLVYSARTPDEVIAREELLRRDADEPHFQLMLTLTRVPGGRRLDAARVAEALARLGPPAHAFVCGGNPFVSAASDLLIDAGVARGLIRTERFGG
>NC_010511.1|WP_012334202.1|4923192_4924587_+|FAD-binding-oxidoreductase
MSPETNHDLVARLAARLGPAGLLTAESDVAPYAVDWRRLFPGRPACVARPASTGEVAEVVRLCREAGAAIVPQGGNTGLAGGAAPDRSGTQVVLSLGRMAAIRAVDPVGLTLTAEAGCVLRTAQDAAAAVNRVLPISFAAEGSAMVGGVVATNAGGLNVVRHGMTRANVLGLEVVLADGSVVAGLRALRKDNAGYDWKQLFVGSEGTLGVITAAVLRLAARPRHVATALLAVPDPEAALRLFTLAQDELGEAIQAFELISGLSLALVARHGGPRNPLGPSPWYVLVEAASSLPALREAAEAVLGAALEQGDAQDGVLAESGQQAAGLWALREGITEAEAKEGRGVKHDVSVPIAAIPAFLAAADRALADKLPGARPNAFGHMGDGNIHYNVLATADQAGEAVNAVVHDVVEAFGGSISAEHGIGQYRAAELVRRRTPEEIALARRIKAALDPEGLLNPGKVLPL
>NC_010511.1|WP_012334203.1|4924643_4925426_-|DUF4198-domain-containing-protein
MFPFRSPRPVAVAVAALAVLTAPARAHDLWLTLSTPEAGPQVRVNFGSPRQRLAPAKPKVIDLQAITPDQTVSLVAPLTPSPPEVPPALVAALPTKAARTLLAATYDSGYWVTLMDGSGRNTSRRLVPDARDSRWAVRFAKAALGPAAPWSKVVGHTLEIVPLEVPAATAGAIRVRVLFRSEPLAGAVVNYGEGSADLDPAQAPRVLTDAEGVATVPIRKAGAQLITARHSVSPSATPDLADRDEYSATFAFRLDEQPVN
>NC_010511.1|WP_012334204.1|4925870_4927067_+|helix-turn-helix-transcriptional-regulator
MPLSQGEFSDLVGRIYDCGRDPELWPDTLARLVEALGAVAGWIGVHDAETGTGRLAVDVGLSPDHRSLYAERFAGLSPLALGTWFTQVGDVVGLSELIDRDAFRGTHFYREWCRPQQVEDLIAGVLTKASGGCGSLSASFDRPVSLEARELMTLLLPHVRRAVETGQLLAEQCGEAEGLSSAMDALSLGVFLLDAAGRVLRANAAAEAILRQGDALRRLPAGTLATAEPWSQGALEGALAACRDDDRTRCRAALPFPSRRGSGPRGGLVGQIVPVRGAACGSRAGRGGEGERQPVAALFVQDPDAAVSIPSEALERLYGLTQGELRVLRGLMQDMTLSEIAEAYGIGVATVRTHLARLFDKTGTRRQAELLRAVMAAAPALRPAEARPGPAGRLAATA
>NC_010511.1|WP_012334205.1|4927289_4928546_-|CCA-tRNA-nucleotidyltransferase
MSLRDAGGLAALLARAPLRKVLDALALPGEETRLVGGAVRDALLGRAVADVDLATTLLPETVMRRAAASGLKPVPTGISHGTVTVVAHGEPFEVTTLREDVETDGRHAVVRYGRDFGRDAARRDFTINALFADAGGHLHDPVGGLPDLAAGRVRFIGDPAQRIREDYLRILRFFRFHARYGRGPLDPAGLAAAIAARDGLATLSRERVRVEMLKLVAAPGAPEVVAVMSATGLLQRLLGGIGDLGRLARLRSRDDPPDPVRRLAALAVQSEADADRLREGLRLSKAEHARLAGAAAALAALHGATEAIDAAALRRQVARHGLPAIIDATMILAGEPRPILDEEARELLASLAAGRIAVPLFPVTGAQLVAGGATPGPGLGRALAAARAAWLAEGCPSDAPARQRLVRLALEAARASDG
>NC_010511.1|WP_012334206.1|4928542_4928800_-|hypothetical-protein
MIRAVADDLILFFLPFALFGIYLVLSRRSPLVWLHWSDHALRLALAGAVLVVGSLLAAGLFAERHGHGFVPTHIENGRVVPGQFR

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Crispr_ID: NC_010511_32

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_010511_32

4969703-4969780

Orphan

Consensus_repeat	Method
GCATCATTCGCCGAAGTGGTCACC	CRISPRCasFinder

1 spacers

The CRISPR arrays of NC_010511_32

>merge|NC_010511|32|4969703-4969780|CRISPRCasFinder
GCATCATTCGCCGAAGTGGTCACCGGTTCGGCGGAAACAATGATGCAAGACCAAGCATCATTCGCCGAAGTGGCCACC

>NC_010511|32|32|4969703-4969780|CRISPRCasFinder
GCATCATTCGCCGAAGTGGTCACC	GGTTCGGCGGAAACAATGATGCAAGACCAA
GCATCATTCGCCGAAGTGGCCACC

Protein	Signature genes	Signature genes Name	Protein_function
NC_010511.1\|WP_012334250.1\|4975168_4976788_+\|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|226641
NC_010511.1\|WP_012334234.1\|4961603_4961975_-\|hypothetical-protein	unknown	unknown	unknown
NC_010511.1\|WP_012334236.1\|4962889_4963846_-\|3-hydroxybutyryl-CoA-dehydrogenase	unknown	unknown	gnl\|CDD\|168796
NC_010511.1\|WP_012334235.1\|4962059_4962893_-\|3-keto-5-aminohexanoate-cleavage-protein	unknown	unknown	gnl\|CDD\|377562
NC_010511.1\|WP_012334247.1\|4972816_4973524_+\|hypothetical-protein	unknown	unknown	unknown
NC_010511.1\|WP_012334246.1\|4972455_4972755_+\|hypothetical-protein	unknown	unknown	unknown
NC_010511.1\|WP_012334232.1\|4956930_4960092_-\|multidrug-efflux-RND-transporter-permease-subunit	unknown	unknown	gnl\|CDD\|273335
NC_010511.1\|WP_012334249.1\|4974152_4975028_-\|lytic-transglycosylase-domain-containing-protein	unknown	unknown	gnl\|CDD\|381594
NC_010511.1\|WP_012334239.1\|4965887_4966691_+\|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|213260
NC_010511.1\|WP_012334240.1\|4966853_4969607_-\|excinuclease-ABC-subunit-UvrB	unknown	unknown	gnl\|CDD\|235395
NC_010511.1\|WP_012334244.1\|4971807_4972080_-\|DUF3297-family-protein	unknown	unknown	gnl\|CDD\|371696
NC_010511.1\|WP_012334237.1\|4963992_4964973_+\|ABC-transporter-substrate-binding-protein	unknown	unknown	gnl\|CDD\|270271
NC_010511.1\|WP_012334231.1\|4956626_4956830_-\|CsbD-family-protein	unknown	unknown	gnl\|CDD\|283241
NC_010511.1\|WP_012334238.1\|4965048_4965882_+\|ABC-transporter-permease	unknown	unknown	gnl\|CDD\|223673
NC_010511.1\|WP_012334251.1\|4976784_4978002_+\|phosphopentomutase	unknown	unknown	gnl\|CDD\|235430
NC_010511.1\|WP_043701498.1\|4973646_4973985_-\|hypothetical-protein	unknown	unknown	unknown
NC_010511.1\|WP_012334241.1\|4969842_4970757_-\|LysR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|176114
NC_010511.1\|WP_012334242.1\|4970908_4971307_+\|DoxX-family-protein	unknown	unknown	gnl\|CDD\|225168
NC_010511.1\|WP_012334233.1\|4960103_4961258_-\|efflux-RND-transporter-periplasmic-adaptor-subunit	unknown	unknown	gnl\|CDD\|184990
NC_010511.1\|WP_012334243.1\|4971317_4971854_+\|glyoxalase	unknown	unknown	gnl\|CDD\|319918

Protein	Function_ID	Function_description	E-value
NC_010511.1\|WP_012334250.1\|4975168_4976788_+\|ABC-transporter-ATP-binding-protein	gnl\|CDD\|226641	COG4172, COG4172, ABC-type uncharacterized transport system, duplicated ATPase component [General function prediction only].	0
NC_010511.1\|WP_012334236.1\|4962889_4963846_-\|3-hydroxybutyryl-CoA-dehydrogenase	gnl\|CDD\|168796	PRK07066, PRK07066, L-carnitine dehydrogenase.	5.91037e-80
NC_010511.1\|WP_012334235.1\|4962059_4962893_-\|3-keto-5-aminohexanoate-cleavage-protein	gnl\|CDD\|377562	pfam05853, BKACE, beta-keto acid cleavage enzyme. BKACE, beta-keto acid cleavage enzyme plays, a role in lysine degradation. In certain instances it catalyzes the conversion of 3-keto-5-aminohexanoate and acetyl-CoA into acetoacetate and 3-aminobutyryl-CoA. The family is found to have at least 14 slightly different potential new enzymatic activities, all of which can therefore be designated as beta-keto acid cleavage enzymes.	6.3702e-83
NC_010511.1\|WP_012334232.1\|4956930_4960092_-\|multidrug-efflux-RND-transporter-permease-subunit	gnl\|CDD\|273335	TIGR00915, Probable_aminoglycoside_efflux_pump, The (Largely Gram-negative Bacterial) Hydrophobe/Amphiphile Efflux-1 (HAE1) Family. Proteins scoring above the trusted cutoff (1000) form a tight clade within the RND (Resistance-Nodulation-Cell Division) superfamily. Proteins scoring greater than the noise cutoff (100) appear to form a larger clade, cleanly separated from more distant homologs that include cadmium/zinc/cobalt resistance transporters. This family is one of several subfamilies within the scope of pfam00873. [Cellular processes, Toxin production and resistance, Transport and binding proteins, Unknown substrate].	0
NC_010511.1\|WP_012334249.1\|4974152_4975028_-\|lytic-transglycosylase-domain-containing-protein	gnl\|CDD\|381594	cd00254, LT-like, lytic transglycosylase(LT)-like domain. Members include the soluble and insoluble membrane-bound LTs in bacteria and LTs in bacteriophage lambda. LTs catalyze the cleavage of the beta-1,4-glycosidic bond between N-acetylmuramic acid (MurNAc) and N-acetyl-D-glucosamine (GlcNAc), as do "goose-type" lysozymes. However, in addition to this, they also make a new glycosidic bond with the C6 hydroxyl group of the same muramic acid residue.	5.32203e-33
NC_010511.1\|WP_012334239.1\|4965887_4966691_+\|ABC-transporter-ATP-binding-protein	gnl\|CDD\|213260	cd03293, ABC_NrtD_SsuB_transporters, ATP-binding cassette domain of the nitrate and sulfonate transporters. NrtD and SsuB are the ATP-binding subunits of the bacterial ABC-type nitrate and sulfonate transport systems, respectively. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.	2.37987e-123
NC_010511.1\|WP_012334240.1\|4966853_4969607_-\|excinuclease-ABC-subunit-UvrB	gnl\|CDD\|235395	PRK05298, PRK05298, excinuclease ABC subunit UvrB.	0
NC_010511.1\|WP_012334244.1\|4971807_4972080_-\|DUF3297-family-protein	gnl\|CDD\|371696	pfam11730, DUF3297, Protein of unknown function (DUF3297). This family is expressed in Proteobacteria and Actinobacteria. The function is not known.	2.05639e-48
NC_010511.1\|WP_012334237.1\|4963992_4964973_+\|ABC-transporter-substrate-binding-protein	gnl\|CDD\|270271	cd13553, PBP2_NrtA_CpmA_like, Substrate binding domain of ABC-type nitrate/bicarbonate transporters, a member of the type 2 periplasmic binding fold superfamily. This subfamily includes nitrate (NrtA) and bicarbonate (CmpA) receptors. These domains are found in eubacterial perisplamic-binding proteins that serve as initial receptors in the ABC transport of bicarbonate, nitrate, taurine, or a wide range of aliphatic sulfonates, while other closest homologs are involved in thiamine (vitamin B1) biosynthetic pathway and desulfurization (DszB). After binding their ligand with high affinity, they interact with a cognate membrane transport complex comprised of two integral membrane domains and two cytoplasmically located ATPase domains. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis. These binding proteins belong to the PBP2 superfamily of periplasmic binding proteins that differ in size and ligand specificity, but have similar tertiary structures consisting of two globular subdomains connected by a flexible hinge. They have been shown to bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap.	2.89969e-38
NC_010511.1\|WP_012334231.1\|4956626_4956830_-\|CsbD-family-protein	gnl\|CDD\|283241	pfam05532, CsbD, CsbD-like. CsbD is a bacterial general stress response protein. It's expression is mediated by sigma-B, an alternative sigma factor. The role of CsbD in stress response is unclear.	2.32881e-09
NC_010511.1\|WP_012334238.1\|4965048_4965882_+\|ABC-transporter-permease	gnl\|CDD\|223673	COG0600, TauC, ABC-type nitrate/sulfonate/bicarbonate transport system, permease component [Inorganic ion transport and metabolism].	2.08922e-78
NC_010511.1\|WP_012334251.1\|4976784_4978002_+\|phosphopentomutase	gnl\|CDD\|235430	PRK05362, PRK05362, phosphopentomutase; Provisional.	0
NC_010511.1\|WP_012334241.1\|4969842_4970757_-\|LysR-family-transcriptional-regulator	gnl\|CDD\|176114	cd08422, PBP2_CrgA_like, The C-terminal substrate binding domain of LysR-type transcriptional regulator CrgA and its related homologs, contains the type 2 periplasmic binding domain. This CD includes the substrate binding domain of LysR-type transcriptional regulator (LTTR) CrgA and its related homologs. The LTTRs are acting as both auto-repressors and activators of target promoters, controlling operons involved in a wide variety of cellular processes such as amino acid biosynthesis, CO2 fixation, antibiotic resistance, degradation of aromatic compounds, nodule formation of nitrogen-fixing bacteria, and synthesis of virulence factors, to name a few. In contrast to the tetrameric form of other LTTRs, CrgA from Neisseria meningitides assembles into an octameric ring, which can bind up to four 63-bp DNA oligonucleotides. Phylogenetic cluster analysis further showed that the CrgA-like regulators form a subclass of the LTTRs that function as octamers. The CrgA is an auto-repressor of its own gene and activates the expression of the mdaB gene which coding for an NADPH-quinone reductase and that its action is increased by MBL (alpha-methylene-gamma-butyrolactone), an inducer of NADPH-quinone oxidoreductase. The structural topology of this substrate-binding domain is most similar to that of the type 2 periplasmic binding proteins (PBP2), which are responsible for the uptake of a variety of substrates such as phosphate, sulfate, polysaccharides, lysine/arginine/ornithine, and histidine. The PBP2 bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap. After binding their specific ligand with high affinity, they can interact with a cognate membrane transport complex comprised of two integral membrane domains and two cytoplasmically located ATPase domains. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis.	1.43923e-76
NC_010511.1\|WP_012334242.1\|4970908_4971307_+\|DoxX-family-protein	gnl\|CDD\|225168	COG2259, COG2259, Predicted membrane protein [Function unknown].	1.38899e-08
NC_010511.1\|WP_012334233.1\|4960103_4961258_-\|efflux-RND-transporter-periplasmic-adaptor-subunit	gnl\|CDD\|184990	PRK15030, PRK15030, multidrug efflux RND transporter periplasmic adaptor subunit AcrA.	6.46955e-97
NC_010511.1\|WP_012334243.1\|4971317_4971854_+\|glyoxalase	gnl\|CDD\|319918	cd07255, VOC_BsCatE_like_N, N-terminal of Bacillus subtilis CatE like protein. Uncharacterized subfamily of VOC superfamily contains Bacillus subtilis CatE and similar proteins. CatE is proposed to function as Catechol-2,3-dioxygenase. VOC is composed of structurally related proteins with paired beta.alpha.beta.beta.beta motifs that provide a metal coordination environment with two or three open or readily accessible coordination sites to promote direct electrophilic participation of the metal ion in catalysis. VOC domain is found in a variety of structurally related metalloproteins, including the bleomycin resistance protein, glyoxalase I, and type I ring-cleaving dioxygenases. A bound metal ion is required for protein activities for the members of this superfamily. A variety of metal ions have been found in the catalytic centers of these proteins including Fe(II), Mn(II), Zn(II), Ni(II) and Mg(II). The protein superfamily contains members with or without domain swapping. The proteins of this family share three conserved metal binding amino acids with the type I extradiol dioxygenases, which shows no domain swapping.	3.18445e-40

>NC_010511.1|WP_012334240.1|4966853_4969607_-|excinuclease-ABC-subunit-UvrB
MPAPKKPRPSSAKASKPELKPLDPFLAELLNPALNRERLPAPEPQAAPEPGPRRRGRPRKAEPGFGEAPQAAFAHGAVTDVDPALAKSLGLRTPDDGPDLAEEPGASLAAAGVSATVDALTKLLTEGNPLFKDGKPWVPHRPERPQKSEGGVAFRLKSDFSPAGDQPKAIADLVEGVRRSERDQVLLGVTGSGKTFTMAKVIEETQRPALILAPNKTLAAQLYGEFKAFFPDNAVEYFVSYYDYYQPEAYVPRSDTFIEKESSINEQIDRMRHSATRALLERDDVIIVASVSCIYGIGSVETYTAMSFTVTLGERIEQRQLIADLVALQYKRIQSDFARGTFRVRGDVIELWPAHLEDRGWRIGLFGDEVEAITEFDPLTGKTINPLKFVKIYANSHYVTPRPTLQQAVKGIKDELKRRVEELTRMGRLIEAQRLEQRCTFDLEMIEATGACNGIENYSRYLTGRKPGEPPPTLFEYLPDNALVFTDESHVTISQIGGMYRGDFRRKATLAEYGFRLPSCLDNRPLRFEEWDAMRPQSIHVSATPAKWEMEQTGGVFVEQVIRPTGLVDPEVIIRPARSQVDDLLGEVKEVAAAGYRTLVTTLTKRMAEDLTEYLHENGVRVRYMHSDIDTLERIEIIRDLRLGAFDVLIGINLLREGLDIPECALVAILDADKEGFLRSETSLIQTIGRAARNAEGRVILYADQRTGSMDRAIAETERRRAKQLAYNAEHGITPQSVKRNIADILESVFERDHVQVDTGLAKGGVTVGHNLKAVMADLEKRMRAAAADLDFEEAARLRDELKRLQATELAIAEDPLARQGAVEDQAGRYGEKGGRRRYGRNADLPPGTGGAEEPLGSGPLGKGVSDEGTRIRRPTLDEMGPGTDREIPIFTERPAARSTQGFPGQRPKYKGRKGRG
>NC_010511.1|WP_012334239.1|4965887_4966691_+|ABC-transporter-ATP-binding-protein
MSRDSAEIAIDRASKVFGAGDHAVVALEGVTAHVPEGEFVCLLGPSGCGKSTLLNAIAGFAPLTGGSIRVGGRPVAEPGPDRGMVFQEYALFPWMTVAQNIRFGLDIKGVGRGEAEAAVARIARTLGLSEFLGRFPKDLSGGMRQRVAIARILALDPPVMLMDEPFGALDALTRRTLQDELLRIWAEYRKTIVFVTHSIEEAIYLADRILVLTYRPGRLKRDIAVPLARPRDTASAEFNALKRDLAGLVMEEQQRFTQAELSGAAVD
>NC_010511.1|WP_012334238.1|4965048_4965882_+|ABC-transporter-permease
MTPRTSFATRLSALRGALLPIGLLILWELASRAGLFSAVVLPPPSAVAARWVQSLVPALPYDPQSQSYGEWLLSGELPHDAVASLGRVVAGFAIGVGLALPVGLLMGTSDRLYGLVNPLLQILRPIPPIAYIPLAIVWFGLGNPPALFLIALGTFFPVLVNTIAGVRQVDSIYIRAARNLGAGPWTLFRRVILPAASPFVLAGMRIGIGTAFIVVIVAEMIAVSDGLGYRILEAREYMWSDKIIGGMLTIGLLGLLIDAAMSRLNDHLLRWHRGLER
>NC_010511.1|WP_012334237.1|4963992_4964973_+|ABC-transporter-substrate-binding-protein
MLTRLAALAAFIAAWAGPASAEDVVRLGNLKFAHYGAISYMKEIAPKYGIRIDEKVFAKGADIYPAMAVDQIDISASGADGAVAARGNGVKLLVVAGFANGGVRILGRPDLGAKTLADIKGKKVATVRGGTQDLMLLAELEKNGLTWSDRPGKDVQLIYFNNYADLNQALAQKYVDVICQSEPQSTQAISAGWGTEIVKPYDTPVGIPYRPLVMTEKMYAEKPDVAARVLKVFVEATKTFIEKPDLAEKYVREQVFKGQLSSQDYKDAMTNAAFTYDIPAGHMQVTADLMHKYGLGKMVSPPKSDAEWVKLDLLEKAKAELGAKTN
>NC_010511.1|WP_012334236.1|4962889_4963846_-|3-hydroxybutyryl-CoA-dehydrogenase
MSESPESVRRVAVIGCGTVGASWAALFLAHGLDVAATDPAPGAEARLLAFVAGARAQLAGFGLRGAGRLDFRASVAEALDGADFVQENAPESEALKRPLLAEIDRLLPARVLVASSTSALLRSAIVADCARPERVLVAHPFNPPHLVPLVEIVAGSEAAAARAAGFYRGLGRRPVILRREMPGHIANRLTAALYREAVNLVAEGVASVADIDAALCHGPGLRWAAMGPHMTYHLGGGPGGIAHYLAHLGPSQERRWASLGRPALTPEVRAAIVAGVAEEAAGLSVAELEARRDRALIEILKARVTVVPEPADAPEDHA
>NC_010511.1|WP_012334235.1|4962059_4962893_-|3-keto-5-aminohexanoate-cleavage-protein
MTKPLIIAVAPNGARLAKSDHPALPLAPREIGLEAARCREAGAAMIHLHVRDAEDRHTLDLDRYREAIAAVRREAGPEMIVQVTTEAVGLYAPAEQMAAIAALRPEAFSVAVRELFAEPDDEAAAASFLAGQARAGTLVQHILYDAGDVTRFQGLVARGLIPLQRASVLFVLGRYSTGQRSQPSDLLPFLAAWNSGHHLDLPWALCAFGRREAACLIAAACLGGDVRVGFENNLWRPDGSLAPDNAAQVAALAALARGLGIEVAGPAVARTLLAARR
>NC_010511.1|WP_012334234.1|4961603_4961975_-|hypothetical-protein
MTRLAPLLRCCAAALLGLAALLLAASTASAAPVGGGPVMRAVTPEMIDASLHADLPAHALRCIASVSAPAEPIRPSDDGAQGASPVATAAPGASASTVILPPRDLGSRPPARAARLDRPPKAA
>NC_010511.1|WP_012334233.1|4960103_4961258_-|efflux-RND-transporter-periplasmic-adaptor-subunit
MHRLALVTAAALLLGACKLEQHDAAAPAEAPPSEVGIVTVRNQPIPFERDLPGRVAPTRIAEVRARVSGLVITRAFQQGSQVKEGDLLYKIDPAPYRVELDSAEATLARAEAALVLARQQAERLETLLSRQTASQAQYDAAYAAQKQAEAEVAGARAARDRAKLNLNWTDVRAPISGRIGRALVTEGALIEQGSATNLATIQQLDPIYVDITQSVSELNKLRRDLASGELASVAPDVATVRLIMDDGSLYPEPGRLLFSDVTADPSTGQVTLRVEIPNPRNELFPGMYVRARIRQGIDADAIAVPQQAVHRSNDGRAEVWLVGENDKVMLHPVEVGPVVEGQWVIREGLKAGDRVVTEGFQKIVAGTVVKPVPWQTAAAGAGRR
>NC_010511.1|WP_012334232.1|4956930_4960092_-|multidrug-efflux-RND-transporter-permease-subunit
MASFFIDRPVFAWVVALFICLGGALTIPLLPVAQYPIIAPPSIALSTAYPGASVEDLYTGTTRLIEDELNGAANIQSFESASDSFGVVEITANFEPGTDPGYAAVEVQNRLKRVEARLPAEVRQQGILVEEASAATLNIITLVSTDGSMDEVALGDFLIRNVINEIRRIPGVGRATLYSTERSLRIWVDPDKLRGLSLSASDVTRAIQNQNAQIASGAVGAQPSPAGHAVNTPIIVKGQMRAPEEFGAIVLRANPDGSTVRLRDVARIELGGEDYKFTTRLNGGEAAGISVTLAPDGNALETAKAIRAKMEELSQFFPSNVKWDIPYDITPAVKASIKKVMMTLVEAVVLVFVVMFLFLQNIRYTLIPTIVVPIALLGTCTVMLLAGFSVNVLTMFGMVLAIGILVDDAIVVVENVERIMNEEGLSPKEATRKAMSQITGAIVGITLVLVAVFIPMAFFPGSVGIIYRQFSIAMVTSIAFSAVLALSLTPALCATMLKPIEKGHGHAKGGVFGWFNRVVERETERYGRGVRWTIAKAGRMMAIYLILVAGVAFAFVRLPEGFLPVEDQGFFTVDIQTPPGASFNRTLAAVKAVEEHLMAQPGVATVTVVNGFSFSGQGQMTSQAFVTLKDWSQRGPDQSAAALVAGTNKALASYKDAVIQALEPPPIDNLGNASGFSFRLQDRAQKGYSALMAAQEQLLSLARKSPVLKNVYVEGLPPAPQAELVIDREKAAALGVSFDEINQTIQVNLGSVYTNDFPNRGKMQRVIVQAEAAQRLNPSDLLNYGVKNQQGTMVPMASFADLTWSVGPAQIIGFNGYQSVRITGEPAAGYTSGEAIAEMERLMTQLPKGFGYTWTGQSLQEKQAGSQATLLLALSVLIVFLCLAALYESWSIPLSVMLVIPLGVVGSVVGVMLRDMPNDVYFKIGLITIIGLSAKNAILIIEFARELWRPGTRLVEATVEAARLRFRPIVMTSLAFIFGVVPLAIAVGAASKSQQAIGTGVMGGMISATVLAVILVPVFFVVVMRLFQRRRVREEEGRPGRTRPAPAREAASH
>NC_010511.1|WP_012334231.1|4956626_4956830_-|CsbD-family-protein
MSSFTDKVKGAANEAAGNIKQGVGNLTGDEKLKAEGKAQELKGEAQRTVGDAKEGIKNAADTVKSKL
>NC_010511.1|WP_012334241.1|4969842_4970757_-|LysR-family-transcriptional-regulator
MLDRVTGMQVFVRVAGLGSFAAAGRSLGLSQTGVTKHVTALEERLGTRLLHRSTRRLTLTEAGRGYLEACERILAEITEAEAAARAEALEPTGTLRLNVPLSFGVREIAPALAAFTAAHPALQVDLGLSDRAVDLIEEGWDMAVRIGHLRDSALVSRFLAPCRLLLCAAPDYLAARGRPRRPEDLGRHNCLGYTLASSGGWRFGGRAYAVTGNLRASNGDALVAAAVAGQGLIYQPSFIVGDALRAGRLVALDLGAPPSVLPIHALMPPGRRQPAKVRACVAFLADRFTGEPVWDRGLPEPVAP
>NC_010511.1|WP_012334242.1|4970908_4971307_+|DoxX-family-protein
MTATRTSPYAALLLRVSLGGLFLAHAGVKLLVFTPAGTAAFFGKLGLPAALAYAVIAAEVLGGLALILGLYARWVALALLPILLGAIVTVHAANGFLAQNPGGGWEFVAFWAVALVVQALLGNGRYAVTREA
>NC_010511.1|WP_012334243.1|4971317_4971854_+|glyoxalase
MGETLTPAPIDPGTRIGHVHLKVADLDRALAFYCGVLGFGLMQRYGHQAAFVSAGGYHHHIGLNTWESRGGPRPAPGTTGLYHAAILYPSRVALADALARLEAAGIPLTGASDHGVSQALYLDDPDRNGLELYWDRPEAEWPRDSAGMLRMTTARLDLASLRALSPRPGASPPGAAAP
>NC_010511.1|WP_012334244.1|4971807_4972080_-|DUF3297-family-protein
MTDTPPDRLCTDPRSPFHDADALERGVGVRFKGVEKTNVEEYCVSEGWVRLAAGNARDRFGNPMTIKLKGPVEPYFRGPRRQEGSPPAEG
>NC_010511.1|WP_012334246.1|4972455_4972755_+|hypothetical-protein
MSGRDLPARELVARALARAFWQTLERNPMPPMAALEAAAGAVGDLYRQVAALHGDRPVCGCGWRPDAEEDLVRLEAALAGAPAEGALPDLAALPAAGTA
>NC_010511.1|WP_012334247.1|4972816_4973524_+|hypothetical-protein
MRGAFDHILRWRLLPGSHAFPGPDGGTCINEAAMVAAGLPYRAIRSSADCPPCFSRPLASYALGLNDAMPDAERPRLMAFVLRLAGSADTVAVEAARTHHLTVQTVRRLLPPVLEQVGLDRHAAACRAAADLAGAVPAARAGAWAAGAVADAAARGGIWVRGARAAAACRAATFAAEIDARSAADAAEAAALFSPDSWAEAVAILDEALGIGRQAPALPVEVARDRMAAARAGAV
>NC_010511.1|WP_043701498.1|4973646_4973985_-|hypothetical-protein
MSREAALAKDLLEDLLDRAARAIGHSRRLHAEAERLRRDCFELTRHFTAQVVGMQLDIVAARGRAAGLAGRRVPADLALRPDAPEPGRHGEGPGRERTATGPPATPRLRALT
>NC_010511.1|WP_012334249.1|4974152_4975028_-|lytic-transglycosylase-domain-containing-protein
MTRALLLCLILPWLLLPALAPRPAAAQPAGAATESVEQALCRLIEGAAQAQSLPVAFLTRLIWRESSFRPGVVSPAGAQGVAQFMPGTAAERGLADPFDPEQAIPHAARLLSDLRRRFGNLGLAAAAYNGGPGRVSSWLAGSGGLPGETRSYVSAITGRTAEDWAAEAKADAKGDLTEPPGTRCLQVTAALRIRGRTETYFADSTPSLAPWGIQLAGNFSKAAALAAFGRARALYASVLGEVRPMVIGTRFRSRGTRAFYRIRVPAETRQAAEGLCNRIRGIGGACLVLKT
>NC_010511.1|WP_012334250.1|4975168_4976788_+|ABC-transporter-ATP-binding-protein
MSAPLLSVQDLSVAFRQGGRETRPVDRVSFEIQPGETLALVGESGSGKSVTALSVLRLLDGATPEGRILFKGRDLLALREAEMRAVRGADITMVFQEPMTSLNPLHRILDQIGEVLRLHRKVPEAGVRARVLELLDLVGIRDAESRLTAYPHELSGGQRQRVMIAMALACEPDLLIADEPTTALDVTVQAQILALLADLKARLGMAMLFITHDLGVVRRVADRVCVMFQGRIVERGEVARVFADPQHDYTRRLLAAEPRGRGNPVAASAETLVEAGPIRVWFPIRQGLLRRTVGHVKAVDGVSVRVRAGETVGVVGESGSGKTTLGLALLRLIGSDGPIVYLGRRLDGLAQGAMRPLRREMQVVFQDPYGSLSPRMSVAEIVEEGLLVQKAGRGAAERRRIVARALEDVGLDPAAMDRYPHEFSGGQRQRIAIARAMALDPRFVVLDEPTSALDMSVQAQIVTLLRELQRRRGLGYLFISHDLKVVRALANRVVVMQNGQVVEEGEAEAIFTAPRTAYTRALFAAAFDLAAAPAGAVRE
>NC_010511.1|WP_012334251.1|4976784_4978002_+|phosphopentomutase
MTRALVIVLDSVGIGGAPDGAAYGDGGADTLGHIAEACAEGRGDRPGLRAGPLRLPHLAGLGLGLAAREASGRMPPGLAPDGPVAGAWGHAVETARGKDTVSGHWEIAGAPVDFDWGRFPATRPSFPPDLTRALIEEGNLPGILGDCHASGTAVIEAYGAEHLRSGKPICYTSVDSVFQIAAHEEAFGLERLYALCGIARRLCDPYRIGRVIARPFAGSAGTGFVRTANRRDFATPPPGDTLLDRLAAAGRPLVSVGKIGDIFAHRHTGTEVKPAGNDACLDAALAAFADLGPGGLVFANLVDFDTEYGHRRDVPGYAAALERFDARLPEIRAALRPGDLCLVTADHGNDPTWTGTDHTREQVPVLAFGPGQRPGPIGRREGLADIGATVAAHLGLALPAGRSWL

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Crispr_ID: NC_010511_33

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_010511_33

5581840-5581960

Orphan

Consensus_repeat	Method
GCCATCCCCGATTTCGGCAACGCGGATGTCGGCGTCGCTC	CRISPRCasFinder

1 spacers

The CRISPR arrays of NC_010511_33

>merge|NC_010511|33|5581840-5581960|CRISPRCasFinder
GCCATCCCCGATTTCGGCAACGCGGATGTCGGCGTCGCTCAGGCGCCGCGCGGGCTCATGCGACATCCGGTCGATGGCTTCGCCATCCCCGATTTCGGCAACGCGGATGTCGGCTTCGCTC

>NC_010511|33|33|5581840-5581960|CRISPRCasFinder
GCCATCCCCGATTTCGGCAACGCGGATGTCGGCGTCGCTC	AGGCGCCGCGCGGGCTCATGCGACATCCGGTCGATGGCTTC
GCCATCCCCGATTTCGGCAACGCGGATGTCGGCTTCGCTC

Protein	Signature genes	Signature genes Name	Protein_function
NC_010511.1\|WP_012334793.1\|5574333_5576208_+\|membrane-protein-insertase-YidC	unknown	unknown	gnl\|CDD\|234942
NC_010511.1\|WP_012334805.1\|5589564_5590758_-\|CoA-transferase	unknown	unknown	gnl\|CDD\|224717
NC_010511.1\|WP_012334807.1\|5593592_5594519_-\|LysR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|176113
NC_010511.1\|WP_012334797.1\|5578160_5580797_-\|ATP-dependent-chaperone-ClpB	unknown	unknown	gnl\|CDD\|274529
NC_010511.1\|WP_012334804.1\|5588647_5589568_-\|hydroxymethylglutaryl-CoA-lyase	unknown	unknown	gnl\|CDD\|163676
NC_010511.1\|WP_010300405.1\|5573636_5573771_+\|50S-ribosomal-protein-L34	unknown	unknown	gnl\|CDD\|366117
NC_010511.1\|WP_012334801.1\|5584953_5586249_-\|nitrate-reductase	unknown	unknown	gnl\|CDD\|132655
NC_010511.1\|WP_012334808.1\|5594690_5595089_+\|DoxX-family-protein	unknown	unknown	gnl\|CDD\|379266
NC_010511.1\|WP_012334802.1\|5586326_5586974_-\|prolyl-oligopeptidase-family-serine-peptidase	unknown	unknown	gnl\|CDD\|223489
NC_010511.1\|WP_012334799.1\|5582014_5582224_-\|hypothetical-protein	unknown	unknown	unknown
NC_010511.1\|WP_012334803.1\|5587170_5588493_-\|MFS-transporter	unknown	unknown	gnl\|CDD\|131385
NC_010511.1\|WP_012334795.1\|5576857_5577262_+\|DUF423-domain-containing-protein	unknown	unknown	gnl\|CDD\|225238
NC_010511.1\|WP_012334792.1\|5573808_5574225_+\|ribonuclease-P-protein-component	unknown	unknown	gnl\|CDD\|376392
NC_010511.1\|WP_012334800.1\|5582570_5584463_-\|flagellin-hook-protein	unknown	unknown	gnl\|CDD\|171664
NC_010511.1\|WP_043701598.1\|5591495_5593430_+\|HAMP-domain-containing-protein	unknown	unknown	gnl\|CDD\|214599
NC_010511.1\|WP_012334796.1\|5577215_5577881_-\|serine/threonine-protein-phosphatase	unknown	unknown	gnl\|CDD\|277316
NC_010511.1\|WP_012334798.1\|5581035_5581809_+\|MOSC-domain-containing-protein	unknown	unknown	gnl\|CDD\|225758
NC_010511.1\|WP_012334791.1\|5573127_5573319_-\|DUF1192-domain-containing-protein	unknown	unknown	gnl\|CDD\|369041
NC_010511.1\|WP_012334794.1\|5576207_5576858_+\|YihA-family-ribosome-biogenesis-GTP-binding-protein	unknown	unknown	gnl\|CDD\|234770
NC_010511.1\|WP_012334790.1\|5572122_5573022_+\|transglutaminase-family-protein	unknown	unknown	gnl\|CDD\|224224

Protein	Function_ID	Function_description	E-value
NC_010511.1\|WP_012334793.1\|5574333_5576208_+\|membrane-protein-insertase-YidC	gnl\|CDD\|234942	PRK01318, PRK01318, membrane protein insertase; Provisional.	0
NC_010511.1\|WP_012334805.1\|5589564_5590758_-\|CoA-transferase	gnl\|CDD\|224717	COG1804, CaiB, Predicted acyl-CoA transferases/carnitine dehydratase [Energy production and conversion].	2.13268e-153
NC_010511.1\|WP_012334807.1\|5593592_5594519_-\|LysR-family-transcriptional-regulator	gnl\|CDD\|176113	cd08421, PBP2_LTTR_like_1, The C-terminal substrate binding domain of an uncharacterized LysR-type transcriptional regulator, contains the type 2 periplasmic binding fold. LysR-transcriptional regulators comprise the largest family of prokaryotic transcription factor. Homologs of some of LTTRs with similar domain organizations are also found in the archaea and eukaryotic organisms. The LTTRs are composed of two functional domains joined by a linker helix involved in oligomerization: an N-terminal HTH (helix-turn-helix) domain, which is responsible for the DNA-binding specificity, and a C-terminal substrate-binding domain, which is structurally homologous to the type 2 periplasmic binding proteins. As also observed in the periplasmic binding proteins, the C-terminal domain of the bacterial transcriptional repressor undergoes a conformational change upon substrate binding which in turn changes the DNA binding affinity of the repressor. The genes controlled by the LTTRs have diverse functional roles including amino acid biosynthesis, CO2 fixation, antibiotic resistance, degradation of aromatic compounds, nodule formation of nitrogen-fixing bacteria, and synthesis of virulence factors, to a name a few. This substrate-binding domain shows significant homology to the type 2 periplasmic binding proteins (PBP2), which are responsible for the uptake of a variety of substrates such as phosphate, sulfate, polysaccharides, lysine/arginine/ornithine, and histidine. The PBP2 bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap. After binding their specific ligand with high affinity, they can interact with a cognate membrane transport complex comprised of two integral membrane domains and two cytoplasmically located ATPase domains. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis.	2.45583e-83
NC_010511.1\|WP_012334797.1\|5578160_5580797_-\|ATP-dependent-chaperone-ClpB	gnl\|CDD\|274529	TIGR03346, chaperone_ClpB, ATP-dependent chaperone ClpB. Members of this protein family are the bacterial ATP-dependent chaperone ClpB. This protein belongs to the AAA family, ATPases associated with various cellular activities (pfam00004). This molecular chaperone does not act as a protease, but rather serves to disaggregate misfolded and aggregated proteins. [Protein fate, Protein folding and stabilization].	0
NC_010511.1\|WP_010300405.1\|5573636_5573771_+\|50S-ribosomal-protein-L34	gnl\|CDD\|366117	pfam00468, Ribosomal_L34, Ribosomal protein L34.	2.08646e-10
NC_010511.1\|WP_043701598.1\|5591495_5593430_+\|HAMP-domain-containing-protein	gnl\|CDD\|214599	smart00283, MA, Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). Thought to undergo reversible methylation in response to attractants or repellants during bacterial chemotaxis.	1.23497e-36
NC_010511.1\|WP_012334800.1\|5582570_5584463_-\|flagellin-hook-protein	gnl\|CDD\|171664	PRK12688, PRK12688, flagellin; Reviewed.	6.27196e-43
NC_010511.1\|WP_012334801.1\|5584953_5586249_-\|nitrate-reductase	gnl\|CDD\|132655	TIGR03616, Putative_pyrimidine_permease_RutG, pyrimidine utilization transport protein G. This protein is observed in operons extremely similar to that characterized in E. coli K-12 responsible for the import and catabolism of pyrimidines, primarily uracil. This protein is a member of the uracil-xanthine permease family defined by TIGR00801. As well as the The Nucleobase:Cation Symporter-2 (NCS2) Family (TC 2.A.40).	1.1737e-160
NC_010511.1\|WP_012334808.1\|5594690_5595089_+\|DoxX-family-protein	gnl\|CDD\|379266	pfam13564, DoxX_2, DoxX-like family. This family of uncharacterized proteins are related to DoxX pfam07681.	3.02657e-13
NC_010511.1\|WP_012334802.1\|5586326_5586974_-\|prolyl-oligopeptidase-family-serine-peptidase	gnl\|CDD\|223489	COG0412, COG0412, Dienelactone hydrolase and related enzymes [Secondary metabolites biosynthesis, transport, and catabolism].	3.0446e-22
NC_010511.1\|WP_012334804.1\|5588647_5589568_-\|hydroxymethylglutaryl-CoA-lyase	gnl\|CDD\|163676	cd07938, DRE_TIM_HMGL, 3-hydroxy-3-methylglutaryl-CoA lyase, catalytic TIM barrel domain. 3-hydroxy-3-methylglutaryl-CoA lyase (HMGL) catalyzes the cleavage of HMG-CoA to acetyl-CoA and acetoacetate, one of the terminal steps in ketone body generation and leucine degradation, and is a key enzyme in the pathway that supplies metabolic fuel to extrahepatic tissues. Mutations in HMGL cause a human autosomal recessive disorder called primary metabolic aciduria that affects ketogenesis and leucine catabolism and can be fatal due to an inability to tolerate hypoglycemia. HMGL has a TIM barrel domain with a catalytic center containing a divalent cation-binding site formed by a cluster of invariant residues that cap the core of the barrel. The cleavage of HMG-CoA requires the presence of a divalent cation like Mg2+ or Mn2+, and the reaction is thought to involve general acid/base catalysis. This family belongs to the DRE-TIM metallolyase superfamily. DRE-TIM metallolyases include 2-isopropylmalate synthase (IPMS), alpha-isopropylmalate synthase (LeuA), 3-hydroxy-3-methylglutaryl-CoA lyase, homocitrate synthase, citramalate synthase, 4-hydroxy-2-oxovalerate aldolase, re-citrate synthase, transcarboxylase 5S, pyruvate carboxylase, AksA, and FrbC. These members all share a conserved triose-phosphate isomerase (TIM) barrel domain consisting of a core beta(8)-alpha(8) motif with the eight parallel beta strands forming an enclosed barrel surrounded by eight alpha helices. The domain has a catalytic center containing a divalent cation-binding site formed by a cluster of invariant residues that cap the core of the barrel. In addition, the catalytic site includes three invariant residues - an aspartate (D), an arginine (R), and a glutamate (E) - which is the basis for the domain name "DRE-TIM".	2.75961e-156
NC_010511.1\|WP_012334803.1\|5587170_5588493_-\|MFS-transporter	gnl\|CDD\|131385	TIGR02332, putative_4-hydroxyphenylacetate_permease, 4-hydroxyphenylacetate permease. This protein is a part of the Major Facilitator Superfamily (pfam07690). Member of this family are found in a number of proteobacterial genomes, but only in the context of having genes for 4-hydroxyphenylacetate (4-HPA) degradation. The protein is characterized by Prieto, et al. ( as 4-hydroxyphenylacetate permease in E. coli, where 3-HPA and 3,4-dihydroxyphenylacetate are shown to competitively inhibit 4-HPA transport and therefore also interact specificially.	1.07161e-82
NC_010511.1\|WP_012334795.1\|5576857_5577262_+\|DUF423-domain-containing-protein	gnl\|CDD\|225238	COG2363, COG2363, Uncharacterized small membrane protein [Function unknown].	1.89849e-12
NC_010511.1\|WP_012334792.1\|5573808_5574225_+\|ribonuclease-P-protein-component	gnl\|CDD\|376392	pfam00825, Ribonuclease_P, Ribonuclease P.	2.12577e-17
NC_010511.1\|WP_012334796.1\|5577215_5577881_-\|serine/threonine-protein-phosphatase	gnl\|CDD\|277316	cd00144, MPP_PPP_family, phosphoprotein phosphatases of the metallophosphatase superfamily, metallophosphatase domain. The PPP (phosphoprotein phosphatase) family is one of two known protein phosphatase families specific for serine and threonine. This family includes: PP1, PP2A, PP2B (calcineurin), PP4, PP5, PP6, PP7, Bsu1, RdgC, PrpE, PrpA/PrpB, and ApA4 hydrolase. The PPP catalytic domain is defined by three conserved motifs (-GDXHG-, -GDXVDRG- and -GNHE-). The PPP enzyme family is ancient with members found in all eukaryotes, and in most bacterial and archeal genomes. Dephosphorylation of phosphoserines and phosphothreonines on target proteins plays a central role in the regulation of many cellular processes. PPPs belong to the metallophosphatase (MPP) superfamily. MPPs are functionally diverse, but all share a conserved domain with an active site consisting of two metal ions (usually manganese, iron, or zinc) coordinated with octahedral geometry by a cage of histidine, aspartate, and asparagine residues. The MPP superfamily includes: Mre11/SbcD-like exonucleases, Dbr1-like RNA lariat debranching enzymes, YfcE-like phosphodiesterases, purple acid phosphatases (PAPs), YbbF-like UDP-2,3-diacylglucosamine hydrolases, and acid sphingomyelinases (ASMases). The conserved domain is a double beta-sheet sandwich with a di-metal active site made up of residues located at the C-terminal side of the sheets. This domain is thought to allow for productive metal coordination.	7.85343e-34
NC_010511.1\|WP_012334798.1\|5581035_5581809_+\|MOSC-domain-containing-protein	gnl\|CDD\|225758	COG3217, COG3217, Uncharacterized Fe-S protein [General function prediction only].	2.17952e-29
NC_010511.1\|WP_012334791.1\|5573127_5573319_-\|DUF1192-domain-containing-protein	gnl\|CDD\|369041	pfam06698, DUF1192, Protein of unknown function (DUF1192). This family consists of several short, hypothetical, bacterial proteins of around 60 residues in length. The function of this family is unknown.	7.21266e-18
NC_010511.1\|WP_012334794.1\|5576207_5576858_+\|YihA-family-ribosome-biogenesis-GTP-binding-protein	gnl\|CDD\|234770	PRK00454, engB, GTP-binding protein YsxC; Reviewed.	1.39144e-102
NC_010511.1\|WP_012334790.1\|5572122_5573022_+\|transglutaminase-family-protein	gnl\|CDD\|224224	COG1305, COG1305, Transglutaminase-like enzymes, putative cysteine proteases [Amino acid transport and metabolism].	6.84665e-45

>NC_010511.1|WP_012334798.1|5581035_5581809_+|MOSC-domain-containing-protein
MPVTLRVAALHRYPVKGLSPEPLEAAELEAGCYFPGDRLFAIENGPSGFDPAAPAHQPKIKFLMLMRDEALARLATRYDDASGTLTIREGDREVLRADLGTREGRLAVEALMRRVVPDALRGPPKLLAAPEGFRFTDSRQGFVSLINLASVAAIEDMVGAPVDPLRFRGNLQVTGLAPFAELDLVGTELAAENGLRLRVTKRTERCAATNVDPATGQRDLAIPRALMRRLGHADCGVYATVVAGGALRRGDALSAAA
>NC_010511.1|WP_012334797.1|5578160_5580797_-|ATP-dependent-chaperone-ClpB
MNFEKYTERARGFVQAAQNLALREGHPQLSPGHVLKVLLDDPEGLCAGLIERAGGQSRVALAQTEAWLAKQPKVSGGASQPQATRDLMRLFDTAEKAAEKAGDSYVTVERLLLALAVEKDSEAGRALAAAGVTAQSLNAAINALRKGRTADNPTAENAYDALKKYARDLTEAAREGKLDPVIGRDEEIRRTIQVLSRRTKNNPVLIGEPGVGKTAIVEGLALRIINGDVPESLRDKQLLALDMGALIAGAKYRGEFEERLKGVLSEVTAAEGGIILFIDEMHTLVGAGKADGAMDASNLLKPALARGELHCVGATTLDEYRKHVEKDAALARRFQPVFVSEPTVEDTVSILRGIKEKYEQHHGVRIQDSALVAAATLSNRYITDRFLPDKAIDLVDEAASRLRMQVDSKPEELDNVDREIVRLKIEAEALKKETDAASRDRLTRLEKELGDLEEQSAAITARWKAEKDKLGRAAELKKKLDEARTELASAQRQGQYQRAGELAYGIIPGLERELGDIEARGPDGSRGNGSGFMEEAVTPNHVAGVVSRWTGVPVDKMLEGEREKLLAMEEALGRRVVGQREAVEAVATAVRRARAGLQDPNRPIGSFMFLGPTGVGKTELTKALASFLFDDETAMVRLDMSEYMEKHSVARLIGAPPGYVGYEEGGALTEAVRRRPYQVVLFDEIEKAHPDVFNVLLQVLDDGRLTDGQGRTVDFRNTLLVMTSNLGAEYLVNQPEGQDTDAVRDEVMAVVRAHFRPEFLNRVDEIILFHRLKRAEMGAIVDIQLGRLQKLLDERKITLDVEPDARAWLAERGYDPAYGARPLKRVIQKSVQDPMAEQILAGSVHDGEAVRVRLGPEGLMIGDVAVTAARRPAGVPLN
>NC_010511.1|WP_012334796.1|5577215_5577881_-|serine/threonine-protein-phosphatase
MDGEGLTYAIGDIHGCADQLDRLLAEIEVHRAGRPRRIVCLGDYVDRGPDSARVIATLRALQEREPGQVTCLKGNHEAMLLGALSGADEPLWLFNGGRAVLASYGVARVDQLPRGDLDWIAALPTLHEDARRWYVHAGFRPGRPAPDPDPEQRLWIREPFLSADYDFGKHVVHGHTPLRSGHPDARHHRTNLDTGAVFGGPLTAGVFTREQAAAVTFLQVR
>NC_010511.1|WP_012334795.1|5576857_5577262_+|DUF423-domain-containing-protein
MPRPERILFALGALAGLLGVAASAAAAHLTGGTLATAAQFLLVHAGPVLALAGLSGSGRLRPGLARPAAACLVLGLVLFSGDLSARALAGHPLFPMAAPTGGLVLMLGWALAALAGLLRVSAPAGTSPPPPARG
>NC_010511.1|WP_012334794.1|5576207_5576858_+|YihA-family-ribosome-biogenesis-GTP-binding-protein
MAGPDEADAALIEAGRLLFAGPADFATASDTLAGLPPMRGLEIAFAGRSNVGKSSLINALTGRNTLARTSHTPGRTQQLNFFDLGGKLTLVDMPGYGYAAVSKAKVASWTELIHAYLQGRANLARVYVLIDARHGIKPNDGEVLDELDAAAVSYQVVLTKGDDLKKGEVASRLDATAAALARRPAAYPEIILTSSRTGEGIPALRASVARLLAERG
>NC_010511.1|WP_012334793.1|5574333_5576208_+|membrane-protein-insertase-YidC
MGNDKTNMIIAIALSLAVLLGWNYFVTAPQVERQRQQQAAQVNPSQGVNPSQGVDPSQGVNASPSPKEGGPSAPVPGTLPGAAGGSPQAALARDEALARAPRVRIDTEALRGSVALKGGRIDDVALKGYHETVDPKSPEIVLLSPAGSANPYYAEFGWVGQNAGPLPGSDTVWTADGDVLTAKKPLVLTFDNGAGLVFRRTLSVDDKYMFTIEDSVENKGPNPVTLYPYGLVSRWGKPHTQGYYVLHEGMIGVVGDKGLQEYTYDKMAKENPLGAPGTRGVSWPGATGGFLGITDKYWAAATIPDQQAPYTGSFTERDEGATKVYQASSLGEARAVAPGASVQASQRLFAGAKEVSTVDAYREKLNIKQFDLLIDWGWFYFITKPMFKALDLFYKLFGNFGVSILVVTLILKLFFLPIANRSYVSMAKMKAVQPEMTAIRERYADDKVKQQQAMMELYKKEKINPVAGCWPVLIQIPVFFSLYKVLFVTIEMRHAPFFGWIRDLAAPDPTSIVNLFGLLPFTPPDLLHLGVWPIVMGITMFLQMKMNPAPPDPVQAQVFTFMPIIFTFMLGSFPAGLVIYWAWNNLLSILQQYWIMRRNGVKVELWDNLRSTFQRRTQVKTAKG
>NC_010511.1|WP_012334792.1|5573808_5574225_+|ribonuclease-P-protein-component
MGAGRPPIGRITRRPDYLAAATGRRFHTGRMTAQGRPRRAEEPATGLRFGFTVTKKTGHATERNRIRRRLKAAAAEIGPEHAERALDLVLIGRREALGAPFEVLVNDIRRALATVTKPKPAGQPGRPRREAAPPEPQP
>NC_010511.1|WP_010300405.1|5573636_5573771_+|50S-ribosomal-protein-L34
MKRTYQPSKLVRKRRHGFRARMATVGGRKVIAARRARGRKRLSA
>NC_010511.1|WP_012334791.1|5573127_5573319_-|DUF1192-domain-containing-protein
MLTDDDRPRPQTSTHVLGQDLTALSLGDLDARIALLRAEIARLEEARRHRQASQEAAKSVFKF
>NC_010511.1|WP_012334790.1|5572122_5573022_+|transglutaminase-family-protein
MIYLLRHVTSYAYRDAVTHARCVLRLTPATGEGQRVLSHQITIQPHSHRRATGADFFGNATTTLTVETPHRAFRIEALSRIDVDRSELPDLASGLAWEEVRERVLAHPSLAPHSPVHFAGPSRRVPLAAEVTAYARASFPPGGGLYAGAVDLMRRIHADFTFDAGATDVATPVAQAFAGRRGVCQDFAHIMIAGLRGLGLPAAYVSGYLRTRPPPGMKRLEGADASHAWVSVWCGDGWHGLDPTNAVAVEDDHIVLATGRDYADVAPVAGIIAGSGSQRLTVAVDVVPEEEARDLAAGA
>NC_010511.1|WP_012334799.1|5582014_5582224_-|hypothetical-protein
MPQTDPLLPRPALTHPAHLAAALARLGRDAGSRREVWRLLTDRYTVDLDAVAAALPPEEPEPIWLPLKG
>NC_010511.1|WP_012334800.1|5582570_5584463_-|flagellin-hook-protein
MSSITLSAATRQNLLSLQDTASLLATTQNRLATGKKVNTALDNPTNYFTADGLTARSAGLSALLDGVSNGIQVIQAANTGITKLKSLTEQLKSVAQQALSSANAFSAKASVASTTLTGATSTNLLSIGPTAAASDAAIGSLPPATAVQLTMTGSVDLSNTAAIQAALFTSSNSLTVTIDGVQVTVNKGIDDASPTALAASITAQLKAAGSSITVAPSGATPNTLVAKGTADGAPFSIGTDAATTKLFGTVTQSSNVFVPTATTLATGLGFQVGDSFTVNGRSVTIARNDTLASLAQKVGTATGGAVTAAYDAVSQKFVFTAADPATTIALGDGGTATGKVANLGFSTTSFGAGLGAGSGTNFKQSPLNGQTITVRVANGTGVTLTFGPAAGQISTLTQLNAALAPANAQATLDPTTGQIKLTTTNEAGADSLTLIASPPPTSNNVANPFNTGTAIATIGGDGLTARNGLVTTYNGLLTQIDQLAADASFNGVNLLAGDNLTLNFNERSTSQLSVTGVNVSAASLGLTPVGQADFVESIAINKVLATINSAASALKNQAASLGANLAVVQNRQDFTKQLITVLDTGAANLTNADMNEEAANSQALQTRTSLGTSALSLANQAQQAILQLLR
>NC_010511.1|WP_012334801.1|5584953_5586249_-|nitrate-reductase
MEQRDRDGPSGWPRWRLSRGGVILSDERPPLGQMLVLALQHVVAMFGSTALAPLLMGFDPNLAILFSGIATLLFFVVVGGRVPSYLGSSFAFIAVVIAATGYGGSGPNPNLPVALGGIVAAGALYALIGGVVMVAGHAWIGRLMPPAVTGAIVGAIGLNLAPIGVKGISGSGLAVGVGLFTVAAVGLAASLPGAARRLPLLIGALAATLLYAGLANGLGLAPPLDLARVAEAPWFGWPRFAAPVFEPAAIALIAPVALVLVAENLGHVKAIAAMTGRDLDPYLGRAFLGDGLATMLSGAFGGTGVTTYAENMGVMAVTRIYSTLVFATAGLVAILFGLSPKFGAAILLIPGPVIGGLAVVVFGLIAATAGRIFVENRVDFSRTRTLLTVGTALVLGAGDFTVSLGQFRLGGIGTATAASILLYHLLRDEPD
>NC_010511.1|WP_012334802.1|5586326_5586974_-|prolyl-oligopeptidase-family-serine-peptidase
MLSFTSGGTRIAVEWFAAGGGPAAPALLLLHGADGLSFAEGYRLAARTFAAAGYPVGFVHYLDRTGDRRVAYSRLRQDFPLWAGTVRDAVGWLARQPGVDAQRIGLVGVSLGAALAFETAASLAGIRAIVDYFGPLPEGLAARRPRLPPTLILHGARDPIVPVAQAHAIARLLAEQGTPHEIRIYPDQGHALVGAAQFDAAARVQRFLQRHLSGA
>NC_010511.1|WP_012334803.1|5587170_5588493_-|MFS-transporter
MAIATAGPLAGIDEVTERSVVRKVAWRLMPLIMICYMVAFFDRINISFAKFQLQSDLGFSNVAYGLGASMFVVGYVIFEVPSNLMLYRVGARRWIARIMISWGIATALMIFIRAEWHFYALRFVIGAMEAGFAPGILYYLTLWFPASHRGRITSFMFVASAFSGIFGAPLAGLILGGLDGALGLTGWQWLFLAGGLPCLLLGALVLTRLEDRVSDARWLSAREKDLLASRIAHHNRDIGDHSLWGAIRQPGFLLIAFVYFLLQVGSYGLNFWGPDLIKTASGGAAASVGLLTAIPYICGAISMVVVGRLSDASGERPKFVAALAVAAALGFFAAGLFDRQIVPLMLALALLGSGIIASIPAFWTLPAKLTTGVGAAGGIALINTLGQFGGIVSPVMVGWVKDLTGSTTPALYGIGALCLLAAILLLTAMPESLRRSDRAA
>NC_010511.1|WP_012334804.1|5588647_5589568_-|hydroxymethylglutaryl-CoA-lyase
MSDAMIVQEVATRDGFQIEPTFVPTPEKIRLIDALSACGFSRIEVSSFVSPKAVPALADAAEIFSGIRRRPGTTYVALVPNPRGAERALAAGADEINLVASASETHNRANMGMTPEASIAGFARIMETVRGAPVSVNATVATAFGCPFEGAQPEDKVLAQVERYRALGVDGVTLADTTGMANPRQVARLVARALALVGPERLTLHFHNTRGSGLANVLAAYEAGARRFDAALGGLGGCPFAPGATGNICTEDLVSMAHEMGVPTGLDLPALIALSRDLPRLVGHDVPGQVAKAGRPCDLHPSPRGA
>NC_010511.1|WP_012334805.1|5589564_5590758_-|CoA-transferase
MSGPLAGIRVLELGQLIAAPFATRLMAEFGAEVIKVEPPGQGDPLRKWRKMHEGTSLWWYLQSRNKKSIAVNLKSPEGLEIVRDLARGADVVVENFRPGGLEKLGLGWDVLSALNPNLVMVRISGYGQTGPYRDRPGFGAIGESMGGIRFTTGSPDAPPARVGVSIGDTLASLHGVIGALMALLRVKTGQGGGQVIDVSLVESVFNVMESLVPEYDLLGEVRTRTGGALPGITPSNTYPTRDGGYVVIAGNSDPIFRRLMAAIGRPDLAEAPALASNDGRSRQAGMLDDAIADWTRARSVEEALAALDAADVPAGRIYSVADIVADPHYQARDMILQAELPGGARVKMPGIVPKLSETPGTVRWQGPALGAHTDAVLTELGLDAERIARLRDAGAVA
>NC_010511.1|WP_043701598.1|5591495_5593430_+|HAMP-domain-containing-protein
MTAALLACSLAAVAVIGAAAYRQQRDATDLAVAAALAERYKSVTAAMADRTQRALGVALTLAHDPAVAEALRRDDRTGLLERYRLLFEPLSAGLNLSFITIHRADGTAFLRYHAPGTFGDSVLARRGTVRDAVAAMRPVSGVEPGRETIAIFAVAPVREAGALRGAADVGLPLGEPFLAEMKGQYGVNLAMHLVRDAAVTTLAATFPGRTLLDPQGHAAAMGTGMHWREATLDGRPVAVMAGPLRNYAGQAIGTIEMALDISDFIAARRAAMLTLVTVLAAVAAAGGLVARRVTRHLVGPIRAITGTMHDLAGGRLRTEIPSTERPDEIGAMARSLQVFRDQLIEAEALRGAQAEGLADRERRTAVIDDLVKRFDASVEAVLCRVSAAATELQATAGQLTATAGGTARQSAAVAQAAGEAAQNVVTVSGAAEELASSVSEIARQVERTESMARGAATEATQAGAIVADLSNAANKIGEVIGLVSGIAQQTNLLALNATIEAARAGEVGKGFAVVAAEVKALAAQTSRATTEIGEQVVWIQTSTGRAVEAIGRIAQTIGSLNETTQAVSGTMRQQHAATGEILGAVTCASGRTSEVTATIREVSDAAAHTGGAAGQVLDASSELAAQTETLRGQVQSFLAAFRAA
>NC_010511.1|WP_012334807.1|5593592_5594519_-|LysR-family-transcriptional-regulator
MAAPGDHPAAATLSRLDLKTLRLFAAICEEGTLNGAARRAAIAPSAVSKRLAELEHALGCALLTREPRGMRPTPAGETLLHHTRRMLASADRIALELAEHAKGVRGIVRMLANLSAIVQFLPEDLRAFLAAQGAIRIDLEERPSTGVVRGVAEGAAEIGICSASVPAQGLATHLYRRDRLVVVMRAGHPLADRAELAFAETLDHDFVGLHAASSIHDSVRAEAQRVGRPLRLRVHVPGFDAVCRMVQADMGLAVVPERVVGLFGAAMQLVAVPLSDAWARRELRLVTRPGRLSPAATLLRDHLAASAS
>NC_010511.1|WP_012334808.1|5594690_5595089_+|DoxX-family-protein
MNATRRGMRTGSLVLRGLITAVFVLAAGMKFAAVPFEVSGFLRFGYPLWFMYAVGAAQLAGAALLWIRGATALGAFLLAAIMAGAVGSHLRAGDPLPMALPALVLLVLLAGLTWSRRHELVAPRPRVAAERA

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Crispr_ID: NC_010511_34

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_010511_34

6319863-6320977

Orphan

Consensus_repeat	Method
GTTTCAATCCGCACCCCCGTGAGGGGGGTGAAC	CRISPRCasFinder
GTTTCAATCCGCACCCCCGTGAGGGGG	CRT
CCCCCTCACGGGGGTGCGGATTGAAAC	PILER-CR

16 spacers

The CRISPR arrays of NC_010511_34

>merge|NC_010511|34|6319863-6320977|CRISPRCasFinder,CRT,PILER-CR
GTTTCAATCCGGACCTCCGGGAGGGGGTGAACTCGGCGCCGGCCTTGCCGTCCTTTAGCGCCTGACAGTTTCAATCCGCACCCCCGTGAGGGGGTGAACCTGAGCCGTGATGTCGGGGTGCCGCGCGCGCCGGAGTTTCAATCCGCACCCCCGTGAGGGGGTGAACCCCGGTCGTCAACTCGCGATTGCAGCCGTCAGAGCCGTTTCAATCCGCACCCCCGTGAGGGGGTGAACGCGGTCGGGTCCCCGAACAGATCCGCCTCGACCAGGTTTCAATCCGCACCCCCGCGAGGGGGTGAACGGGGATGGCCCCTCGGCCAGCACGCGTCGCAGGAGTTTCAATCCGCACCCCCGTGAGGGGGTGAACCCGGACGGTGACGGTGCCCGCACCCATCTCGTTAGGGTTTCAATCCGCACCCCCGTGAGGGGGTGAACCAGGACGGCCAGGGCGGCGCGCTGCTCTTCCTCAAGTTTCAATCCGCACCCTCGTGAGGGGGTGACCCCCCGGTAGCAGTGCTCTTTCAGCTCATCGATCACGTTTCAATCCGCACCCCCGTGAGGGGGGTGAACCGCCCGCCGCTCGTCTACGTGGTGGCCGCGGTGGAGTTTCAATCCGCACCCCCGTGAGGGGGGTGAACACGGGGCCGGGCTCTCCCGGGACACCGCCAACCTGTTTCAATCCGCACCCCCGTGAGGGGGGGGGTGAACCGGGCCGAGCCGCTCGGTGTACTTGATGATGTTCATGTTTCAATTCGCACCCCCGTGAGGGGGGTGAACCACTGCGGTGCACGGTCTCGGTCTTGTGCTCCAGTTTCAATCCGCACCCCCGTGAGGGGGGTGAACCCGTTGCCGGCCGGCGACACCGTGATGTCAAGCTGTGTTTCAATCCGCACCCCCGTGAGGGGGGTGAACGCGCCCTGCCGCCCGGCTGGCGCGCCCTGACCGAGGTTTCAATCCGCACCCCCGTGAAGGGGGTGAACCCTGCAGCAGCAGCAGCGACACCATGTGCGTGTTGTTTCAATCCGCACCCCCGTGAGGGGGGTGAACCCGCCCGCGCCCGTCGCGCGCCACGCGGTGTCGGCGTTTCAATCCGCACCCCCGTGAGGGGGGTGAAC

>NC_010511|34|34|6319863-6320977|CRISPRCasFinder
GTTTCAATCCGGACCTCCGGGAGGGGGTGAACT	CGGCGCCGGCCTTGCCGTCCTTTAGCGCCTGACA
GTTTCAATCCGCACCCCCGTGAGGGGGTGAACC	TGAGCCGTGATGTCGGGGTGCCGCGCGCGCCGGA
GTTTCAATCCGCACCCCCGTGAGGGGGTGAACC	CCGGTCGTCAACTCGCGATTGCAGCCGTCAGAGCC
GTTTCAATCCGCACCCCCGTGAGGGGGTGAACG	CGGTCGGGTCCCCGAACAGATCCGCCTCGACCAG
GTTTCAATCCGCACCCCCGCGAGGGGGTGAACG	GGGATGGCCCCTCGGCCAGCACGCGTCGCAGGA
GTTTCAATCCGCACCCCCGTGAGGGGGTGAACC	CGGACGGTGACGGTGCCCGCACCCATCTCGTTAGG
GTTTCAATCCGCACCCCCGTGAGGGGGTGAACC	AGGACGGCCAGGGCGGCGCGCTGCTCTTCCTCAA
GTTTCAATCCGCACCCTCGTGAGGGGGTGACCC	CCCGGTAGCAGTGCTCTTTCAGCTCATCGATCAC
GTTTCAATCCGCACCCCCGTGAGGGGGGTGAAC	CGCCCGCCGCTCGTCTACGTGGTGGCCGCGGTGGA
GTTTCAATCCGCACCCCCGTGAGGGGGGTGAAC	ACGGGGCCGGGCTCTCCCGGGACACCGCCAACCT
GTTTCAATCCGCACCCCCGTGAGGGGGGGGGTG	AACCGGGCCGAGCCGCTCGGTGTACTTGATGATGTTCAT
GTTTCAATTCGCACCCCCGTGAGGGGGGTGAAC	CACTGCGGTGCACGGTCTCGGTCTTGTGCTCCA
GTTTCAATCCGCACCCCCGTGAGGGGGGTGAAC	CCGTTGCCGGCCGGCGACACCGTGATGTCAAGCTGT
GTTTCAATCCGCACCCCCGTGAGGGGGGTGAAC	GCGCCCTGCCGCCCGGCTGGCGCGCCCTGACCGAG
GTTTCAATCCGCACCCCCGTGAAGGGGGTGAAC	CCTGCAGCAGCAGCAGCGACACCATGTGCGTGTT
GTTTCAATCCGCACCCCCGTGAGGGGGGTGAAC	CCGCCCGCGCCCGTCGCGCGCCACGCGGTGTCGGC
GTTTCAATCCGCACCCCCGTGAGGGGGGTGAAC

>NC_010511|34|3|6319863-6320971|CRT
GTTTCAATCCGGACCTCCGGGAGGGGG	TGAACTCGGCGCCGGCCTTGCCGTCCTTTAGCGCCTGACA
GTTTCAATCCGCACCCCCGTGAGGGGG	TGAACCTGAGCCGTGATGTCGGGGTGCCGCGCGCGCCGGA
GTTTCAATCCGCACCCCCGTGAGGGGG	TGAACCCCGGTCGTCAACTCGCGATTGCAGCCGTCAGAGCC
GTTTCAATCCGCACCCCCGTGAGGGGG	TGAACGCGGTCGGGTCCCCGAACAGATCCGCCTCGACCAG
GTTTCAATCCGCACCCCCGCGAGGGGG	TGAACGGGGATGGCCCCTCGGCCAGCACGCGTCGCAGGA
GTTTCAATCCGCACCCCCGTGAGGGGG	TGAACCCGGACGGTGACGGTGCCCGCACCCATCTCGTTAGG
GTTTCAATCCGCACCCCCGTGAGGGGG	TGAACCAGGACGGCCAGGGCGGCGCGCTGCTCTTCCTCAA
GTTTCAATCCGCACCCTCGTGAGGGGG	TGACCCCCCGGTAGCAGTGCTCTTTCAGCTCATCGATCAC
GTTTCAATCCGCACCCCCGTGAGGGGG	GTGAACCGCCCGCCGCTCGTCTACGTGGTGGCCGCGGTGGA
GTTTCAATCCGCACCCCCGTGAGGGGG	GTGAACACGGGGCCGGGCTCTCCCGGGACACCGCCAACCT
GTTTCAATCCGCACCCCCGTGAGGGGG	GGGGTGAACCGGGCCGAGCCGCTCGGTGTACTTGATGATGTTCAT
GTTTCAATTCGCACCCCCGTGAGGGGG	GTGAACCACTGCGGTGCACGGTCTCGGTCTTGTGCTCCA
GTTTCAATCCGCACCCCCGTGAGGGGG	GTGAACCCGTTGCCGGCCGGCGACACCGTGATGTCAAGCTGT
GTTTCAATCCGCACCCCCGTGAGGGGG	GTGAACGCGCCCTGCCGCCCGGCTGGCGCGCCCTGACCGAG
GTTTCAATCCGCACCCCCGTGAAGGGG	GTGAACCCTGCAGCAGCAGCAGCGACACCATGTGCGTGTT
GTTTCAATCCGCACCCCCGTGAGGGGG	GTGAACCCGCCCGCGCCCGTCGCGCGCCACGCGGTGTCGGC
GTTTCAATCCGCACCCCCGTGAGGGGG

>NC_010511|34|3|6319930-6320971|PILER-CR
GTTTCAATCCGCACCCCCGTGAGGGGG	TGAACCTGAGCCGTGATGTCGGGGTGCCGCGCGCGCCGGA
GTTTCAATCCGCACCCCCGTGAGGGGG	TGAACCCCGGTCGTCAACTCGCGATTGCAGCCGTCAGAGCC
GTTTCAATCCGCACCCCCGTGAGGGGG	TGAACGCGGTCGGGTCCCCGAACAGATCCGCCTCGACCAG
GTTTCAATCCGCACCCCCGCGAGGGGG	TGAACGGGGATGGCCCCTCGGCCAGCACGCGTCGCAGGA
GTTTCAATCCGCACCCCCGTGAGGGGG	TGAACCCGGACGGTGACGGTGCCCGCACCCATCTCGTTAGG
GTTTCAATCCGCACCCCCGTGAGGGGG	TGAACCAGGACGGCCAGGGCGGCGCGCTGCTCTTCCTCAA
GTTTCAATCCGCACCCTCGTGAGGGGG	TGACCCCCCGGTAGCAGTGCTCTTTCAGCTCATCGATCAC
GTTTCAATCCGCACCCCCGTGAGGGGG	GTGAACCGCCCGCCGCTCGTCTACGTGGTGGCCGCGGTGGA
GTTTCAATCCGCACCCCCGTGAGGGGG	GTGAACACGGGGCCGGGCTCTCCCGGGACACCGCCAACCT
GTTTCAATCCGCACCCCCGTGAGGGGG	GGGGTGAACCGGGCCGAGCCGCTCGGTGTACTTGATGATGTTCAT
GTTTCAATTCGCACCCCCGTGAGGGGG	GTGAACCACTGCGGTGCACGGTCTCGGTCTTGTGCTCCA
GTTTCAATCCGCACCCCCGTGAGGGGG	GTGAACCCGTTGCCGGCCGGCGACACCGTGATGTCAAGCTGT
GTTTCAATCCGCACCCCCGTGAGGGGG	GTGAACGCGCCCTGCCGCCCGGCTGGCGCGCCCTGACCGAG
GTTTCAATCCGCACCCCCGTGAAGGGG	GTGAACCCTGCAGCAGCAGCAGCGACACCATGTGCGTGTT
GTTTCAATCCGCACCCCCGTGAGGGGG	GTGAACCCGCCCGCGCCCGTCGCGCGCCACGCGGTGTCGGC
GTTTCAATCCGCACCCCCGTGAGGGGG

Protein	Signature genes	Signature genes Name	Protein_function
NC_010511.1\|WP_012335434.1\|6328567_6329707_+\|pyrroloquinoline-quinone-biosynthesis-protein-PqqE	unknown	unknown	gnl\|CDD\|235397
NC_010511.1\|WP_050777521.1\|6327392_6328193_+\|pyrroloquinoline-quinone-synthase-PqqC	unknown	unknown	gnl\|CDD\|235353
NC_010511.1\|WP_012335419.1\|6315932_6316544_+\|c-type-cytochrome,-methanol-metabolism-related	unknown	unknown	gnl\|CDD\|163586
NC_010511.1\|WP_012335429.1\|6325774_6325864_+\|pyrroloquinoline-quinone-precursor-peptide-PqqA	unknown	unknown	gnl\|CDD\|178960
NC_010511.1\|WP_043702740.1\|6316579_6317440_+\|quinoprotein-dehydrogenase-associated-putative-ABC-transporter-substrate-binding-protein	unknown	unknown	gnl\|CDD\|274828
NC_010511.1\|WP_012335423.1\|6318537_6318918_-\|dihydroneopterin-aldolase	unknown	unknown	gnl\|CDD\|224456
NC_010511.1\|WP_012335431.1\|6326077_6326977_+\|pyrroloquinoline-quinone-biosynthesis-protein-PqqB	unknown	unknown	gnl\|CDD\|235361
NC_010511.1\|WP_012335426.1\|6322135_6323068_-\|cyclase-family-protein	unknown	unknown	gnl\|CDD\|377240
NC_010511.1\|WP_012335430.1\|6325939_6326029_+\|pyrroloquinoline-quinone-precursor-peptide-PqqA	unknown	unknown	gnl\|CDD\|178960
NC_010511.1\|WP_012335427.1\|6323206_6324787_+\|HAMP-domain-containing-protein	unknown	unknown	gnl\|CDD\|223715
NC_010511.1\|WP_012335424.1\|6318917_6319805_-\|dihydropteroate-synthase	unknown	unknown	gnl\|CDD\|238380
NC_010511.1\|WP_012335415.1\|6311080_6311815_+\|ABC-transporter-permease-subunit	unknown	unknown	gnl\|CDD\|223673
NC_010511.1\|WP_012335422.1\|6318048_6318525_-\|2-amino-4-hydroxy-6--hydroxymethyldihydropteridine-diphosphokinase	unknown	unknown	gnl\|CDD\|223872
NC_010511.1\|WP_012335428.1\|6324830_6325535_+\|response-regulator-transcription-factor	unknown	unknown	gnl\|CDD\|223816
NC_010511.1\|WP_012335417.1\|6312576_6313542_+\|quinoprotein-relay-system-zinc-metallohydrolase-2	unknown	unknown	gnl\|CDD\|275352
NC_010511.1\|WP_012335421.1\|6317436_6317970_+\|PQQ-dependent-catabolism-associated-CXXCW-motif-protein	unknown	unknown	gnl\|CDD\|274823
NC_010511.1\|WP_012335416.1\|6311819_6312560_+\|ATP-binding-cassette-domain-containing-protein	unknown	unknown	gnl\|CDD\|213260
NC_010511.1\|WP_012335418.1\|6313994_6315794_+\|methanol/ethanol-family-PQQ-dependent-dehydrogenase	unknown	unknown	gnl\|CDD\|199836
NC_010511.1\|WP_012335433.1\|6328189_6328477_+\|pyrroloquinoline-quinone-biosynthesis-peptide-chaperone-PqqD	unknown	unknown	gnl\|CDD\|274818
NC_010511.1\|WP_012335425.1\|6321319_6322129_+\|quinoprotein-dehydrogenase-associated-SoxYZ-like-carrier	unknown	unknown	gnl\|CDD\|275350

Protein	Function_ID	Function_description	E-value
NC_010511.1\|WP_012335434.1\|6328567_6329707_+\|pyrroloquinoline-quinone-biosynthesis-protein-PqqE	gnl\|CDD\|235397	PRK05301, PRK05301, pyrroloquinoline quinone biosynthesis protein PqqE; Provisional.	0
NC_010511.1\|WP_050777521.1\|6327392_6328193_+\|pyrroloquinoline-quinone-synthase-PqqC	gnl\|CDD\|235353	PRK05157, PRK05157, pyrroloquinoline quinone biosynthesis protein PqqC; Provisional.	9.91763e-160
NC_010511.1\|WP_012335419.1\|6315932_6316544_+\|c-type-cytochrome,-methanol-metabolism-related	gnl\|CDD\|163586	TIGR03874, 4cys_cytochr, c-type cytochrome, methanol metabolism-related. This family represents a c-type cytochrome related to (but excluding) cytochrome c-555 of Methylococcus capsulatus. Members contain four invariant Cys residues, including two from a heme-binding motif shared with c-555, and two others.	9.15955e-84
NC_010511.1\|WP_012335429.1\|6325774_6325864_+\|pyrroloquinoline-quinone-precursor-peptide-PqqA	gnl\|CDD\|178960	PRK00284, pqqA, pyrroloquinoline quinone precursor peptide PqqA.	2.84562e-06
NC_010511.1\|WP_043702740.1\|6316579_6317440_+\|quinoprotein-dehydrogenase-associated-putative-ABC-transporter-substrate-binding-protein	gnl\|CDD\|274828	TIGR03871, extracellular_solute-binding_protein_family_3, quinoprotein dehydrogenase-associated probable ABC transporter substrate-binding protein. This protein family, a sister family to TIGR03870, is found more broadly. It occurs a range of PQQ-biosynthesizing species, not just in known methanotrophs. Interpretation of evidence by homology and by direct experimental work suggest two different roles. By homology, this family appears to be the periplasmic substrate-binding protein of an ABC transport family. However, mutational studies and direct characterization for some sequences related to this family suggests this family may act as a maturation chaperone or additional subunit of a methanol dehydrogenase-like enzyme.	1.55015e-114
NC_010511.1\|WP_012335423.1\|6318537_6318918_-\|dihydroneopterin-aldolase	gnl\|CDD\|224456	COG1539, FolB, Dihydroneopterin aldolase [Coenzyme metabolism].	8.96795e-44
NC_010511.1\|WP_012335431.1\|6326077_6326977_+\|pyrroloquinoline-quinone-biosynthesis-protein-PqqB	gnl\|CDD\|235361	PRK05184, PRK05184, pyrroloquinoline quinone biosynthesis protein PqqB; Provisional.	2.45712e-173
NC_010511.1\|WP_012335426.1\|6322135_6323068_-\|cyclase-family-protein	gnl\|CDD\|377240	pfam04199, Cyclase, Putative cyclase. Proteins in this family are thought to be cyclase enzymes. They are found in proteins involved in antibiotic synthesis. However they are also found in organisms that do not make antibiotics pointing to a wider role for these proteins. The proteins contain a conserved motif HXGTHXDXPXH that is likely to form part of the active site.	2.13684e-39
NC_010511.1\|WP_012335430.1\|6325939_6326029_+\|pyrroloquinoline-quinone-precursor-peptide-PqqA	gnl\|CDD\|178960	PRK00284, pqqA, pyrroloquinoline quinone precursor peptide PqqA.	2.72821e-06
NC_010511.1\|WP_012335427.1\|6323206_6324787_+\|HAMP-domain-containing-protein	gnl\|CDD\|223715	COG0642, BaeS, Signal transduction histidine kinase [Signal transduction mechanisms].	8.49418e-42
NC_010511.1\|WP_012335424.1\|6318917_6319805_-\|dihydropteroate-synthase	gnl\|CDD\|238380	cd00739, DHPS, DHPS subgroup of Pterin binding enzymes. DHPS (dihydropteroate synthase), a functional homodimer, catalyzes the condensation of p-aminobenzoic acid (pABA) in the de novo biosynthesis of folate, which is an essential cofactor in both nucleic acid and protein biosynthesis. Prokaryotes (and some lower eukaryotes) must synthesize folate de novo, while higher eukaryotes are able to utilize dietary folate and therefore lack DHPS. Sulfonamide drugs, which are substrate analogs of pABA, target DHPS.	3.90771e-107
NC_010511.1\|WP_012335415.1\|6311080_6311815_+\|ABC-transporter-permease-subunit	gnl\|CDD\|223673	COG0600, TauC, ABC-type nitrate/sulfonate/bicarbonate transport system, permease component [Inorganic ion transport and metabolism].	2.97934e-40
NC_010511.1\|WP_012335422.1\|6318048_6318525_-\|2-amino-4-hydroxy-6--hydroxymethyldihydropteridine-diphosphokinase	gnl\|CDD\|223872	COG0801, FolK, 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase [Coenzyme metabolism].	5.83788e-67
NC_010511.1\|WP_012335428.1\|6324830_6325535_+\|response-regulator-transcription-factor	gnl\|CDD\|223816	COG0745, OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain [Signal transduction mechanisms / Transcription].	3.53647e-71
NC_010511.1\|WP_012335417.1\|6312576_6313542_+\|quinoprotein-relay-system-zinc-metallohydrolase-2	gnl\|CDD\|275352	TIGR04559, metallo-beta-lactamase_family_protein, quinoprotein relay system zinc metallohydrolase 2. By homology, members are Zn metallohydrolases in the same family as the SoxH protein associated with sulfate metabolism, Bacillus cereus beta-lactamase II (see PDB:1bc2), and, more distantly, hydroxyacylglutathione hydrolase (glyoxalase II). All members occur in genomes with both PQQ biosynthesis and a PQQ-dependent (quinoprotein) dehydrogenase that has a motif of two consecutive Cys residues (see TIGR03075). The Cys-Cys motif is associated with electron transfer by specialized cytochromes such as c551. All these genomes also include a fusion protein (TIGR04557) whose domains resemble SoxY and SoxZ from thiosulfate oxidation. A conserved Cys in this fusion protein aligns to the Cys residue in SoxY that carries sulfur cycle intermediates. In many genomes, the genes for PQQ biosynthesis enzymes, PQQ-dependent enzymes, their associated cytochromes, and members of this family are clustered. Note that one to three closely related Zn metallohydrolases may occur; this family represents a specific clade among them. Some members of this family have a short additional N-terminal domain with four conserved Cys residues. [Unknown function, Enzymes of unknown specificity].	1.46877e-162
NC_010511.1\|WP_012335421.1\|6317436_6317970_+\|PQQ-dependent-catabolism-associated-CXXCW-motif-protein	gnl\|CDD\|274823	TIGR03865, PQQ_CXXCW, PQQ-dependent catabolism-associated CXXCW motif protein. Members of this protein family have a CXXXCW motif, consistent with a possible role in redox cofactor binding. This protein family shows strong relationships by phylogenetic profiling and conserved gene neighborhoods with a transport system for alcohols metabolized by PQQ-dependent enzymes.	3.41188e-74
NC_010511.1\|WP_012335416.1\|6311819_6312560_+\|ATP-binding-cassette-domain-containing-protein	gnl\|CDD\|213260	cd03293, ABC_NrtD_SsuB_transporters, ATP-binding cassette domain of the nitrate and sulfonate transporters. NrtD and SsuB are the ATP-binding subunits of the bacterial ABC-type nitrate and sulfonate transport systems, respectively. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.	2.53468e-69
NC_010511.1\|WP_012335418.1\|6313994_6315794_+\|methanol/ethanol-family-PQQ-dependent-dehydrogenase	gnl\|CDD\|199836	cd10278, PQQ_MDH, Large subunit of methanol dehydrogenase (moxF). Methanol dehydrogenase is a key enzyme in the utilization of C1 compounds as a source of energy and carbon by bacteria. It catalyzes the oxidation of methanol to formaldehyde, transfering two electrons per methanol to cytochrome c(L) as the acceptor. Methanol dehydrogenase belongs to a family of dehydrogenases with pyrroloquinoline quinone (PQQ) as cofactor, which also includes dehydrogenases specific to other alcohols and membrane-bound glucose dehydrogenases. This alignment model for the large subunit contains an 8-bladed beta-propeller; the functional enzyme forms a heterotetramer composed of two large and two small subunits.	0
NC_010511.1\|WP_012335433.1\|6328189_6328477_+\|pyrroloquinoline-quinone-biosynthesis-peptide-chaperone-PqqD	gnl\|CDD\|274818	TIGR03859, PQQ_PqqD, coenzyme PQQ biosynthesis protein PqqD. This model identifies PqqD, a protein involved in the final steps of the biosynthesis of pyrroloquinoline quinone, coenzyme PQQ. [Biosynthesis of cofactors, prosthetic groups, and carriers, Other].	5.26712e-21
NC_010511.1\|WP_012335425.1\|6321319_6322129_+\|quinoprotein-dehydrogenase-associated-SoxYZ-like-carrier	gnl\|CDD\|275350	TIGR04557, hypothetical_protein, quinoprotein dehydrogenase-associated SoxYZ-like carrier. Members of this family are fusion proteins, with the N-terminal region similar to the sulfur oxidation protein SoxY (TIGR04488) and the C-terminal region similar to sulfur oxidation protein SoxZ (TIGR04490). Members occur exclusively in species with PQQ-dependent enzymes that have a Cys-Cys motif (TIGR03075) for electron transfer to c550 family cytochrome. By homology to the sulfur moiety-binding subunit SoxY, we predict the conserved Cys in the Gly-Gly-Cys motif binds some unknown adduct.	2.24487e-112

>NC_010511.1|WP_012335424.1|6318917_6319805_-|dihydropteroate-synthase
MTASPSALAALLPDLGRRTLVMGILNVTPDSFSDGGRFQAREAAERQAASLVQEGAAILDIGGESTRPGHVPVSAEEEQARILPVLAAVAPACPVPISIDTYKASTAEVALKAGARIVNDVWGLQREPDIARVAAAHGAPVIVMHNRESPDPSLDIVEEMKRFFDRSLAIAAKAGIPERDIVLDPGIGFGKSWEQHLDAVRRLPELRALGFPLLVGISRKSLLGRIHNTGTAPADRLFGSIAAHVVAATLGADIVRAHDVRPHVEACQVVDALMRRDGGVRRDGDPRRDAAAGAP
>NC_010511.1|WP_012335423.1|6318537_6318918_-|dihydroneopterin-aldolase
MADRILVHRLAVFAHHGVLEEENRLGQRFYLSLDAHLDLREAGRRDDIAASVSYADLAALAGEIATTRRFRLIEALAEAVAAACLARFPALTAITVRVDKPGAPVPAILDGVAVEVTRTRQDRSPS
>NC_010511.1|WP_012335422.1|6318048_6318525_-|2-amino-4-hydroxy-6--hydroxymethyldihydropteridine-diphosphokinase
MTDAYLGLGSNLGDKAAMLEAAIAGLDAAPGLRVTARSRFYRTPPWGDTDQDWFLNAAVAVATDLTPHALLDACLALEARLGRVRARRWGPRVIDIDVLHYAGAAVEDERLVLPHRFVRARAFVLVPLAEIAPDLVIGGETVTAALAKLDRTGIEPVE
>NC_010511.1|WP_012335421.1|6317436_6317970_+|PQQ-dependent-catabolism-associated-CXXCW-motif-protein
MRALLVLALLAAAGPAGAAPVPEPPGYREDAFRTPTPATLRGARVVTTEEAEALWRAGVAFVDVMPQPPRPAALPPGTIWRDPPHESIPGAHWLANTGFGALAPETEAYFRRELDRLTGGDRGKPLVFFCLRNCWMSWNAAKRALSYGYGQVIWFPDGTDGWSDAALPLERLQPVTP
>NC_010511.1|WP_043702740.1|6316579_6317440_+|quinoprotein-dehydrogenase-associated-putative-ABC-transporter-substrate-binding-protein
MAGFRPAGWLAASLAALLLAAGPGPAGAQQLPDLVTTDALRVCGDPANMPFSDRKGEGFENRIAAILADELKVKLRTYWLTQGPGFVRNTLGSGLCDVIVGSALGTDLVQNTNPYYRSAYVLVSRRGDLSGVAALDDPRLKGKVIGVVAGTPPVNRMGEVGLVSSMRPYPPYQFDPSNAHQTVSAQIVADLAEKRLDAAILWGPAAGWLARQSGVPMEVVPLLKEPDRPALTYRIAMGVRLNENDWKRTLNTALRKRRAEIEQVLRDYAVPLLDEEENRLLDPRAP
>NC_010511.1|WP_012335419.1|6315932_6316544_+|c-type-cytochrome,-methanol-metabolism-related
MRHLSTTALRPVLAGLALATVSVVAVYAEEAKSADPALANSLNPNDKTAEIDQPVLDKAKAVKVEDGKYLDADGHPTFHVTDNGKKFDWYSYSGYRRYHAECHVCHGPDGMGSTYAPALKDSLKNLSYEEFIGILVGGKQDVNAAQQKVMPAFGDNKNVMCYADDLYVYLRARAAGAMGRVRPGDKEEKPEAAKKAEKECLGG
>NC_010511.1|WP_012335418.1|6313994_6315794_+|methanol/ethanol-family-PQQ-dependent-dehydrogenase
MRAVHLLALSAGILGVTPALADDLQKEINNPAQQVLQTVDYANTRFSKLDQINTGNVNKLQVAWTFSTGVLRGHEGAPLVVGDMMYVHTPFPNIVYALDLNQDGKIVWKYEPKQDPNVIPVMCCDTVNRGLAYADGKIILHQADTTVVALDAKTGKVAWSVVNGDPKKGETNTATVLPVKDKVIVGISGGEYGVRCHVTAYSLKDGKKIWRGYSMGPDDEMLVNPEKTTSLGKPVGKDSSLKTWEGDQWKQGGGCTWGWYSYDPKLNLMYYGSGNPSTWNPKQRPGDNKWSMTVWARDVDSGEAKWVYQMTPHDEWDYDGINEMILTDQKVGDKERPLLTHFDRNGFGYTLDRATGELLVAEKYDPVVNWASKVDMDKSSKTYGRPLVQAKYSTEQNGEDVNSKGICPAALGSKDQQPAAYSPKTNLFYVPTNHVCMDYEPFRVSYTPGQPYVGATLSMYPAPNSHGGMGNFIAWDGVNGKIKWSVPEQFSVWSGALATAGDVVFYGTLEGYLKAVDAKSGKELYKFKTPSGIIGNVMTYEHKGKQNVAVLSGVGGWAGIGLAAGLTDPNAGLGAVGGYAALSNYTNLGGQLTVFTLPN
>NC_010511.1|WP_012335417.1|6312576_6313542_+|quinoprotein-relay-system-zinc-metallohydrolase-2
MRAIPRWLLAATLSATAALPTPPAARAEAPAPPGPAEAAPLPMREVAPGILVYAAPYALASRDNEGAIANVGFVVGRDAVAVIDTGGSLLAGRRLLAAVRARTALPIRYVINTHVHPDHVLGNAAFAGEGATFVGHRNLPEALAARAGSYLQSNADLVGPGFAGTRIVPPTLLVEERRELDLGGRVLRLDAWPTAHTNSDLTVRDLATDTWFLGDLLFVGHVPALDGRLEGWIAVLRRLRAEPAARVVPGHGPASVSWPAASGPIERYLTTLETEVRAMVRDGRPIGEAGTAAAGEASEWSLFRDFNARNATTAYQELEWD
>NC_010511.1|WP_012335416.1|6311819_6312560_+|ATP-binding-cassette-domain-containing-protein
MSAAGADPALSVAIRRKTYAARGERVEAVRDLAFAVEPGETLCLIGPSGAGKTTTLRILLGLDRDFEGRVSPDPATLRIGIVFQEPRLLPWRSVEQNVRLALPRAERGRPLDGLFEELGLTPWRDRFPGELSLGMARRVALARALALEPRLLVLDEPFVSLDDAAAAALRAAVFGAARRRRAAVLMVTHNVPEALEVADRLLLLTPRPARLAATIPLTTPRAERGRAWQEATRRDLAARYPEAVAA
>NC_010511.1|WP_012335415.1|6311080_6311815_+|ABC-transporter-permease-subunit
MALATRLASALLLLIAWFLASRFTDLRTLPSPEAVTAFVWREAQGGDLPRNVGITLLRVAASFLLAMTTGAVLGILLGRSRAADRLLDTPLIVLLNTPALVITVLAYIWLGLTETAAILAVALNKMPNVAVIMREGARGLDPGLQEMAQAFRFDRRTWIRHVLLPQLEPFAVAAARSGLSLAWKIVLVVELLGRPNGVGYAISYYFQLFDVAALIGYSLVFSAVMLAVDLLLLQPLDAHVRRWR
>NC_010511.1|WP_012335425.1|6321319_6322129_+|quinoprotein-dehydrogenase-associated-SoxYZ-like-carrier
MIRAFWRPALAGAALSVLAATAVAAQPAAQEDARAEAAWTELRPNVTGDRPIQDGAGVLSLDTPRRAEDAAIVPVGIRIALPEGDGRAVKRLTLVVDENPSPVVGTFTFPTPQHRFELSTRIRVNSYSYVRAIAETEDGALYMTKAYVKAAGGCSAPAVKDPAEAKANLGKMRFRAFAERGEAQVQVRHPNYSGLQMDQVTRLYTPAWFVETLSVRQGETPLFTLTGGISVSEDPTFRFTFAGNGEPVTVVAKDTEGRTFTQSFPASGS
>NC_010511.1|WP_012335426.1|6322135_6323068_-|cyclase-family-protein
MMMTGRFWAAALALALAAPARAEDTSLWRLYEQTLKRAKYIDLTHAFAPTQPVWPGFAAATVRAARAGRTIEGFVEKGEAFTYARHGFVVTAYDLPTDQYGTQLDPPAHWNPLGATISDLPATYALRPLVVIDISPQVARDEGYHLQVADIAAWEARHGRIPEGAVVMVRSDWSKRWAETERFRAKPFPGVSLAALQVLHLERRILFHGHEPLDTDTTPNLEGEAWLMHHNFAQAEGVANLDKVPEAGALVAIGFAKPLGGTGGFARYVAIAPPGWPEGVSVEEAPGAPLPTQPAPLVRGPDGVMRPTPP
>NC_010511.1|WP_012335427.1|6323206_6324787_+|HAMP-domain-containing-protein
MGSLRVRFGLLVGSAAALVLLAAGGLFWSLAAAERTLDSTLEAQVRLELIAELSGRLTEYGLAAVEAVGETPSRPERLATARDEVDRALNAVDEGLNRAIARSDAIVDRTQYAARSRPLARLRAARVMLDRQVAQIQREPDPVKRSDAIRGALNAFGAVTGPPLTFLVEAERRGVESAAGEVRALAVRLRALALAVAGLAVVVLLLVHRTLTRPLLRRIDDIRAGAAAIGRGELDTRLPVAAHDELGLLVASFNRMAARLKRRESRVAAARAALEETVAQATAELRAANTRLEEIDRSRRRFFADVSHELRTPLTVILGECDLAARSPDTPEAFRPVIATIRKRALRLHRRVGDMLRIARSESGQIELERKPVSLAAVLTEAVENCASEARRRRIALAFEPSETDVEIQADPEWLRQIVEGLIDNALRHAAGATRVWVVLRARRDGAEVTVADDGPGFPAEAETLFERFRRGGNSSPAQGFGIGLALARWVVERHDGVIRLGSGGDEARGARVTLVLPADAREDAA
>NC_010511.1|WP_012335428.1|6324830_6325535_+|response-regulator-transcription-factor
MTSVLVVEDDGDIRGMLARGLSAEGFSVNLAGSVDEALAAARERVPEAVLLDIMLPDGSGHEVCRSLREGGYPGAILFLSAKDEVSDRVDGLAVGADDYIVKPFAFDELLARLRTHLQRRRAAGEPRTLLSAGRLSLDLATRQVRFGETTARLTQREAELLTVLMEHANRPVTRGDIFDRLWANQGGLSLNVVDVYVGYLRTKLGDVARAGGPAIVTVRGKGFMLDLHEPSFRQ
>NC_010511.1|WP_012335429.1|6325774_6325864_+|pyrroloquinoline-quinone-precursor-peptide-PqqA
MKWALPVVAEVCVGMEVTSYESAEIDPFN
>NC_010511.1|WP_012335430.1|6325939_6326029_+|pyrroloquinoline-quinone-precursor-peptide-PqqA
MKWALPVVAEICVGMEVTSYESAEIDPFN
>NC_010511.1|WP_012335431.1|6326077_6326977_+|pyrroloquinoline-quinone-biosynthesis-protein-PqqB
MQAIILGSAAGGGVPQWNCRCPHCTMAWAGDARVKPRTQSSLAVSPDGETWLLVNASPDIRQQLFATPALHPARGLRHSPIAAVLLTNGDVDHVAGLLTLRESQPFRLHATRNILDSVSANRVFDVLAPEHVARREVALDESFAPVPGLAVTLFAVPGKVPLWLEEGTPEIGQETETTVGALIEAGGKRLAYVPGCARVTDDLRRRLSGVDVLLFDGTVYLDDDMIRAGVGTKTGWRMGHVPMTGEGGAIAALAEVPIGRRIFVHINNTNPVLVEESEARRAVEAEGWTVAHDGLTLTL
>NC_010511.1|WP_050777521.1|6327392_6328193_+|pyrroloquinoline-quinone-synthase-PqqC
MTAALSLTLPAAPAANDASLLSPAALEAALRDIGARRYHNLHPFHRLLHDGKLDKDQVRAWALNRYYYQAMIPVKDSAILARMPDANLRRIWRQRIVDHDGDHEGDGGIERWLKLAEGVGFDRAYVLSTRGILPTTRFAVEAYVHFVAERSLLEAIASSLTEMFSPTIISERVAGMLKNYDFITKETLAYFDKRLTQAPRDADFALAYVKEHATTPALQRQALDALTFKCNVLWSQLDALYFAYVAPGMIPPDAWRPGEGLVEGRA
>NC_010511.1|WP_012335433.1|6328189_6328477_+|pyrroloquinoline-quinone-biosynthesis-peptide-chaperone-PqqD
MSLTPGDVPRLPRGVRMRFDGVRGAHVLLAPERTFDLDQNAVAVLSLVDGERSIRAIAEALSAQYDAPVGVIEPDVITMLNGLAEKRVLEAKPAA
>NC_010511.1|WP_012335434.1|6328567_6329707_+|pyrroloquinoline-quinone-biosynthesis-protein-PqqE
MTAVTPTLPAPIGLLAELTHRCPLRCPYCSNPLELDKRSAELDTATWQRVLGEAAALGVLHVHLSGGEPTARQDIVEITGACADLGLYSNLITSGVGGALAKLDALSEAGLDHVQLSIQAAEAGNAERIGGLRNAQPQKFAFAERVVALGLPLTLNAVIHRGNIDEVPALIDLAVRLGAKRLEVAHTQYYGWAYVNRAALMPAKPDVDRSIRVVEEARERLKGRLVIDLVVPDYYAKYPKACAGGWGRRLMNVTPSGKVLPCHAAETIPGLAFWNVQERALGDIWANSPAFQAYRGTSWMKEPCRSCDRREKDWGGCRCQALALAGDAAATDPACSLSPLHAKVQALAVAESALETAPDYQYRTIGGAPVVPQPEGVSA

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Crispr_ID: NC_010511_35

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_010511_35

6365050-6365147

Orphan

Consensus_repeat	Method
CAAGCCCGCGCGGCGCGTGAGCGAAACCGA	CRISPRCasFinder

1 spacers

The CRISPR arrays of NC_010511_35

>merge|NC_010511|35|6365050-6365147|CRISPRCasFinder
CAAGCCCGCGCGGCGCGTGAGCGAAACCGAAATCCGCATTGCGAAGCAATCCATCGGATTTCGTATGGCAAGCCCGCGCGGCGCGTGAGCGAAGCCGA

>NC_010511|35|35|6365050-6365147|CRISPRCasFinder
CAAGCCCGCGCGGCGCGTGAGCGAAACCGA	AATCCGCATTGCGAAGCAATCCATCGGATTTCGTATGG
CAAGCCCGCGCGGCGCGTGAGCGAAGCCGA

Protein	Signature genes	Signature genes Name	Protein_function
NC_010511.1\|WP_012335464.1\|6374375_6374681_+\|hypothetical-protein	unknown	unknown	unknown
NC_010511.1\|WP_012335461.1\|6372681_6373428_+\|hypothetical-protein	unknown	unknown	unknown
NC_010511.1\|WP_012335456.1\|6367924_6368146_-\|hypothetical-protein	unknown	unknown	unknown
NC_010511.1\|WP_043701713.1\|6360493_6362347_-\|ShlB/FhaC/HecB-family-hemolysin-secretion/activation-protein	unknown	unknown	gnl\|CDD\|225387
NC_010511.1\|WP_012335445.1\|6339893_6341048_+\|ATP-grasp-domain-containing-protein	unknown	unknown	gnl\|CDD\|225141
NC_010511.1\|WP_012335450.1\|6345079_6345697_-\|invasion-protein	unknown	unknown	gnl\|CDD\|369076
NC_010511.1\|WP_012335448.1\|6343131_6343992_+\|triphosphoribosyl-dephospho-CoA-synthase	unknown	unknown	gnl\|CDD\|376637
NC_010511.1\|WP_012335462.1\|6373409_6373688_-\|hypothetical-protein	unknown	unknown	unknown
NC_010511.1\|WP_018263818.1\|6372293_6372473_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|274090
NC_010511.1\|WP_012335453.1\|6363164_6363893_-\|nickel-transporter	unknown	unknown	gnl\|CDD\|240074
NC_010511.1\|WP_012335449.1\|6344239_6344755_+\|formaldehyde-activating-enzyme	unknown	unknown	gnl\|CDD\|132170
NC_010511.1\|WP_012335458.1\|6371780_6371993_+\|hypothetical-protein	unknown	unknown	unknown
NC_010511.1\|WP_012335446.1\|6341044_6342019_+\|methenyltetrahydromethanopterin-cyclohydrolase	unknown	unknown	gnl\|CDD\|235020
NC_010511.1\|WP_012335463.1\|6373892_6374201_+\|hypothetical-protein	unknown	unknown	unknown
NC_010511.1\|WP_012335454.1\|6363934_6364996_+\|H4MPT-linked-C1-transfer-pathway-protein	unknown	unknown	gnl\|CDD\|163144
NC_010511.1\|WP_012335451.1\|6345909_6360477_-\|filamentous-hemagglutinin-N-terminal-domain-containing-protein	unknown	unknown	gnl\|CDD\|273865
NC_010511.1\|WP_012335457.1\|6370586_6371378_+\|calcium-transporter-ChaC	unknown	unknown	gnl\|CDD\|226226
NC_010511.1\|WP_012335455.1\|6365175_6367701_-\|EAL-domain-containing-protein	unknown	unknown	gnl\|CDD\|236645
NC_010511.1\|WP_012335465.1\|6374694_6375759_-\|aromatic-ring-hydroxylating-dioxygenase-subunit-alpha	unknown	unknown	gnl\|CDD\|226985
NC_010511.1\|WP_012335447.1\|6342214_6343132_+\|RimK-family-alpha-L-glutamate-ligase	unknown	unknown	gnl\|CDD\|273261

Protein	Function_ID	Function_description	E-value
NC_010511.1\|WP_043701713.1\|6360493_6362347_-\|ShlB/FhaC/HecB-family-hemolysin-secretion/activation-protein	gnl\|CDD\|225387	COG2831, FhaC, Hemolysin activation/secretion protein [Intracellular trafficking and secretion].	2.5135e-51
NC_010511.1\|WP_012335445.1\|6339893_6341048_+\|ATP-grasp-domain-containing-protein	gnl\|CDD\|225141	COG2232, COG2232, Predicted ATP-dependent carboligase related to biotin carboxylase [General function prediction only].	8.22337e-22
NC_010511.1\|WP_012335450.1\|6345079_6345697_-\|invasion-protein	gnl\|CDD\|369076	pfam06776, IalB, Invasion associated locus B (IalB) protein. This family consists of several invasion associated locus B (IalB) proteins and related sequences. IalB is known to be a major virulence factor in Bartonella bacilliformis where it was shown to have a direct role in human erythrocyte parasitism. IalB is upregulated in response to environmental cues signaling vector-to-host transmission. Such environmental cues would include, but not be limited to, temperature, pH, oxidative stress, and haemin limitation. It is also thought that IalB would aide B. bacilliformis survival under stress-inducing environmental conditions. The role of this protein in other bacterial species is unknown.	6.72724e-21
NC_010511.1\|WP_012335448.1\|6343131_6343992_+\|triphosphoribosyl-dephospho-CoA-synthase	gnl\|CDD\|376637	pfam01874, CitG, ATP:dephospho-CoA triphosphoribosyl transferase. The citG gene is found in a gene cluster with citrate lyase subunits. The function of the CitG protein was elucidated as ATP:dephospho-CoA triphosphoribosyl transferase.	5.51129e-62
NC_010511.1\|WP_012335465.1\|6374694_6375759_-\|aromatic-ring-hydroxylating-dioxygenase-subunit-alpha	gnl\|CDD\|226985	COG4638, HcaE, Phenylpropionate dioxygenase and related ring-hydroxylating dioxygenases, large terminal subunit [Inorganic ion transport and metabolism / General function prediction only].	4.53908e-39
NC_010511.1\|WP_018263818.1\|6372293_6372473_+\|hypothetical-protein	gnl\|CDD\|274090	TIGR02349, Chaperone_protein_DnaJ, chaperone protein DnaJ. This model represents bacterial forms of DnaJ, part of the DnaK-DnaJ-GrpE chaperone system. The three components typically are encoded by consecutive genes. DnaJ homologs occur in many genomes, typically not near DnaK and GrpE-like genes; most such genes are not included by this family. Eukaryotic (mitochondrial and chloroplast) forms are not included in the scope of this family.	9.33747e-05
NC_010511.1\|WP_012335453.1\|6363164_6363893_-\|nickel-transporter	gnl\|CDD\|240074	cd04723, HisA_HisF, Phosphoribosylformimino-5-aminoimidazole carboxamide ribonucleotide (ProFAR) isomerase (HisA) and the cyclase subunit of imidazoleglycerol phosphate synthase (HisF). The ProFAR isomerase catalyzes the fourth step in histidine biosynthesis, an isomerisation of the aminoaldose moiety of ProFAR to the aminoketose of PRFAR (N-(5'-phospho-D-1'-ribulosylformimino)-5-amino-1-(5''-phospho-ribosyl)-4-imidazolecarboxamide). In bacteria and archaea, ProFAR isomerase is encoded by the HisA gene. The Imidazole glycerol phosphate synthase (IGPS) catalyzes the fifth step of histidine biosynthesis, the formation of the imidazole ring. IGPS converts N1-(5'-phosphoribulosyl)-formimino-5-aminoimidazole-4-carboxamide ribonucleotide (PRFAR) to imidazole glycerol phosphate (ImGP) and 5'-(5-aminoimidazole-4-carboxamide) ribonucleotide (AICAR). This conversion involves two tightly coupled reactions in distinct active sites of IGPS. The two catalytic domains can be fused, like in fungi and plants, or peformed by a heterodimer (HisH-glutaminase and HisF-cyclase), like in bacteria.	2.4157e-62
NC_010511.1\|WP_012335449.1\|6344239_6344755_+\|formaldehyde-activating-enzyme	gnl\|CDD\|132170	TIGR03126, one_C_fae, formaldehyde-activating enzyme. This family consists of formaldehyde-activating enzyme, or the corresponding domain of longer, bifunctional proteins. It links formaldehyde to the C1 carrier tetrahydromethanopterin (H4MPT), an analog of tetrahydrofolate, and is common among species with H4MPT. The ribulose monophosphate (RuMP) pathway, which removes the toxic metabolite formaldehyde by assimilation, runs in the opposite direction in some species to produce ribulose 5-phosphate for nucleotide biosynthesis, leaving formaldehyde as an additional metabolite. In these species, formaldehyde activating enzyme may occur as a fusion protein with D-arabino 3-hexulose 6-phosphate formaldehyde lyase from the RuMP pathway.	1.10226e-92
NC_010511.1\|WP_012335446.1\|6341044_6342019_+\|methenyltetrahydromethanopterin-cyclohydrolase	gnl\|CDD\|235020	PRK02264, PRK02264, N(5),N(10)-methenyltetrahydromethanopterin cyclohydrolase; Provisional.	6.27496e-163
NC_010511.1\|WP_012335454.1\|6363934_6364996_+\|H4MPT-linked-C1-transfer-pathway-protein	gnl\|CDD\|163144	TIGR03123, one_C_unchar_1, probable H4MPT-linked C1 transfer pathway protein. This protein family was identified, by the method of partial phylogenetic profiling, as related to the use of tetrahydromethanopterin (H4MPT) as a C-1 carrier. Characteristic markers of the H4MPT-linked C1 transfer pathway include formylmethanofuran dehydrogenase subunits, methenyltetrahydromethanopterin cyclohydrolase, etc. Tetrahydromethanopterin, a tetrahydrofolate analog, occurs in methanogenic archaea, bacterial methanotrophs, planctomycetes, and a few other lineages. [Central intermediary metabolism, One-carbon metabolism].	5.15927e-126
NC_010511.1\|WP_012335451.1\|6345909_6360477_-\|filamentous-hemagglutinin-N-terminal-domain-containing-protein	gnl\|CDD\|273865	TIGR01901, Heme/hemopexin-binding_protein, filamentous hemagglutinin family N-terminal domain. This model represents a conserved domain found near the N-terminus of a number of large, repetitive bacterial proteins, including many proteins of over 2500 amino acids. Members generally have a signal sequence, then an intervening region, then the region described by this model. Following this region, proteins typically have regions rich in repeats but may show no homology between the repeats of one member and the repeats of another. A number of the members of this family have been designated adhesins, filamentous haemagglutinins, heme/hemopexin-binding protein, etc.	9.85644e-18
NC_010511.1\|WP_012335457.1\|6370586_6371378_+\|calcium-transporter-ChaC	gnl\|CDD\|226226	COG3703, ChaC, Uncharacterized protein involved in cation transport [Inorganic ion transport and metabolism].	1.558e-57
NC_010511.1\|WP_012335455.1\|6365175_6367701_-\|EAL-domain-containing-protein	gnl\|CDD\|236645	PRK10060, PRK10060, cyclic di-GMP phosphodiesterase.	1.76952e-97
NC_010511.1\|WP_012335447.1\|6342214_6343132_+\|RimK-family-alpha-L-glutamate-ligase	gnl\|CDD\|273261	TIGR00768, Tetrahydromethanopterin:alpha-L-glutamate_ligase, alpha-L-glutamate ligase, RimK family. This family, related to bacterial glutathione synthetases, contains at least three different alpha-L-glutamate ligases. One is RimK, as in E. coli, which adds additional Glu residues to the native Glu-Glu C-terminus of ribosomal protein S6, but not to Lys-Glu mutants. Most species with a member of this subfamily lack an S6 homolog ending in Glu-Glu, however. Members in Methanococcus jannaschii act instead as a tetrahydromethanopterin:alpha-l-glutamate ligase (MJ0620) and a gamma-F420-2:alpha-l-glutamate ligase (MJ1001).	9.52214e-50

>NC_010511.1|WP_012335454.1|6363934_6364996_+|H4MPT-linked-C1-transfer-pathway-protein
MSLPHDSASAARIIGWDLGGVHVKAALVEEGAVRAVVQAPCPLWRGLSALDAALAGLPDWARGPAHHAVTMTGELTDCFADRADGVAQLAAWADRSLSGPVAIYAGRSGFVAPEAAAPAAAEIASANWYATAALVGRLVPEALLVDIGSTTADLIPVAAGQPAARGYSDAERLETGELVYTGVVRTPLLALSPWAPFRGRRTALMAETFAATGDVHRLLGDLPAEEDQQDTMDLKGKSRPETETRLARMIGRDRHEGSPADWSRLAGHFAEAQLRLLHDAAAVILSRGDLPARAPVIACGAGRFVATRLAARLGRPVRDLADLIAPHLAAGAEAWASTCGPAVAVAWLARPAG
>NC_010511.1|WP_012335453.1|6363164_6363893_-|nickel-transporter
MSGGAGASPIAGREPVAIIPVLDLRRGQVVRARAGERHAYAPIRTPLSASADPGAVAAGLLAAWPARRLYVADLDAIMEGAPPDRAALRAVAAAAPGVELWVDAGFAGEAAVAAFLEAGLGRPVLGSESQGDPDLVRRLGDAAILSLDSRDGAPLGPAALHEDPSLWPSEIIVMALGRVGSGAGPDLAGIAAVRARAPAARLYAAGGLRGPEDLAGLRAAGAAGILVASALHDGRLRPEHLS
>NC_010511.1|WP_043701713.1|6360493_6362347_-|ShlB/FhaC/HecB-family-hemolysin-secretion/activation-protein
MGIMMQDSTARGRAAVAGRAGPWPAMAIGALAAAAAGLVPARAQTASQITPPSFRPAPQARGAGLVIPEGAGPEAPPGAERVSVRLGAVAAEGTLPALEGATRALADRLAAGPVTLAQIFAAARDLEQAYAAEGYALVRVVLPAQALRDGGALRLVVIDGTLERIDTAALPPEIRDRVAALLAPLAGRRGLRLAEIERGLMLAGDTPGTVLRSTLAPGTAPGSSILVVEARYKPVTGMVGVDNTLSDALGRNPASLGLEMNSPTGHGEQLYLRAGGAAIPAGQASLFSPRPLNRSLAAGLILPLGGDGLTLNLEATDARTTAKPRPGNPAFTSDFSRYSARLRYPLIRARDLTLAAEASFDAQEERLTVIRPIEAPFSLDRLRVARASGDALWVLPTDGVLTARLTGSFGLDGLGARAAPLPGPGVVPLSRQGARPDFQKLEASLGLAQPLAEHLALDLRARAQTSFNQALPRAEQFGIASLSGLSSFDSGLFQGDEGYVLRGEVQFPFVASVPMPFRLPSLPAQLGTGFQEAESAAAGLVATPYGFGAFGLVRQQRPTSLERPMVRGASYGLGLRLAASPQASFTNLSASLEYGRSARSDRLPAEDRVTFSVTLQF
>NC_010511.1|WP_012335451.1|6345909_6360477_-|filamentous-hemagglutinin-N-terminal-domain-containing-protein
MPVRSLAPRLLAALLATTALTRTAPAQTLPSGGQVVAGSVSIGAPRNGALTVTQASPNAIVNWQGFSIGQGGRVEFRQPDAQAAILNRVTGTTPSTIAGQLTANGQVYLVNPNGIAITPTGRVEAGAFVASSLGITDGDFLAGRRSFRGSGASAPVTQAGTLTIARGGYAALIGGEVANSGVITVPAGKVGLGSGEEATLDLAGDGFLQVAVPTRRAGAGALVAHSGVISAEGGTVTLRAAAAREMARQAVNLSGVVEARSFTTRGGTILLSGGDGQVEVGAAARLDASGGPQGGRVRIRGREVSVAGRIEASGARGGRVGIRAGESLALSGVLAAAGRSGAGGSVVATAPAMALSLARIDVSGAAGGGRVRLGGGRQGQGGLAHATTLSVDAGSEIRAEATARGAGGDVVLWSDGRTDFSGTIVATGGRLGGDGGAAEVSSKGVLAYRGRTDLTAPAGAAGTLLLDPYDLTISGAADSGLSGFAAAANDSVLSVGTLQTALGSANVTVTTGTGGSQAGDITVADPVTWSGGTTLTLAAARHVAVNANLTGGTGAQIVLRADAAGSGTGTVTFGSGVQATASGGVALYYNPADYATPTNYGPNVGTGTVLSAWMLVNTAQNLQDISKNLSGGYALGRDIDASETAGWNNGSGFAPLGSDTRRFKGLFDGQGHVITGLLINRGGTSNIGLFGVVDGSAAVRNVGLVGGSMTGIGNVGGLVGTNYGSISQASASVSVTGGSALGGLVGANSGSITQAYATGSVTGANTLGGLVGNNAGSISQAYATGSVTGASTVGGLVGNVTSGTITQAYATGSVTGASTVGGLVGNVTSGSIGQAYASGRVMGTDTVGGLVGSLQSGVTVTASYWTTQTTGQGTSAGGMGTGLTTVGARQTSSYTGWNFTTDWYQAGDLRPIGRWEAAQPGADGVIPIATLHQLQLMGANLAGRYRLTADIDAGATMRAAAGADASGVFGPGGFVPVGDYTAPFSGSLDGAGHVITGLTIARSSQSYVGLIGQLAPGGGLTRIGLVGGSVSGSSNVGGLAGSNAGTISQAYSTASVSASRSAAGGLVGYNSGMISQAYATGSVSGWTQIGGLVGYNSGPISQAYATGSVTGSNQIGGLVAYNGGTVSESYASGPLSGTSDIGGLIGTGTGSVTSSYWDTNTTLQASSAGGGTGLTTAQARAQGGYAGWNFTTDWYQTADLRPIGRWEAAPAGADGAIPIATLHQLQLVATNPAGRYRLAADLDARATAGTNAADLWGGGGFVPIGDASTGFAGTFDGGGHAIAGLTINRPTLDNVGLFGVTGAGSLVRGIGLDGGSVTGGSTVGGLVGANSGRITQASATVSVTGTRTVGGLVGYNSGSITQASATGGVTGTRTVGGLVGTNGGSITQAYATGGVTGTRTVGGLVGTNGGSITQAYATGGVTGTSTVGGLVGASAGSILQTYASGHVTGTDGVGGLVGSSNGTVLASFWDTETTGQAASAGGSGATGLTTASARQAASYADWNFTTDWYQAGDLRPIGRWEAAQPGADGTALITNLHQLQLVAANLAGSYVLAADLDASATAGAGAADIWGPGGFVPIGTPSARFTGLFDGRGGVIRGLTINRPSINVVGLFTATGAGSLVRGIGLVGGSVTGGLTVGGLVGTNSGSITQAYATVSVTGTRNVGGLVGYNSGSITQASATGRVTGGVNVGGLVGFNSGAIRQTYASGRVTGTGGVGGLVGSSNGTVLASFWDTETTGQAASAGGSGAAGLTPASARQAASYAGWNFTMDWYQAGDLRPIGRWEAAQPGADGVIPISTLHQLQLMGTNLAGRYRLTADIDAGATMKAAAGADASEVFGPGGFVPVGDETAPFSGSLDGAGHVVTGLTIARPSQDAVGLIGKLASGGGLTRIGLVGGSVSGSSQVGSLVGTNSGTISQAYSTASVSGSQTGSQVGGLVGFSRGWISQAYATGSVSGTSKVGGLVGYNSATISQAYASGSVTGDSFVGGLVGGNAGGSIQQTYASGRVTGGVGVGGLLGFSMGNVSSSFWDTESTGQATSAGGSGASGLTTASARQAASYAGWNFTTDWYQAGDLRPIGRWEAAQPGADGPALITTLHQLQLVAANLAGSYALAADLDAGATAGADAADIWGPGGFVPLGGSAAGFSGRFDGRGRAISGLTINTPTSDFVGLFGAVSAAGRVARIGLAGSRIIGRDKVGALAGSSDGTIFQASATGRVSGGTGVGGLVGSSSGRIAQASATGSVYGSGTSVGGLVGAVTAGTLSQAYATGEVTGGADVGGLVGSNGGSIAQSYASGLVVALADPSKAGGLVGTGTGSVTSSYWDTNTTLQASSAGGGTGLTTAQARDQGGYAGWNFTSDWYQAADLRPIGRWEAAQPGADGPALITNLHQLQLVAANLAGSYALAADLDASATAGAVAADIWGPGGFVPIGTPSARFSGLFDGRGGVIRGLTINRPTLDNVSLFGVTGPGSLVRGIGLDGGSVTGRSNVGGLAGKNVAGTITQVYASGSVTGDTFVGGLVGTTSGSITQVFATGSVTGASYVGGLVGYTSGGGITQAYATGSVTGSKNVGGLVGYAGGSITQAYASGRVTGDSAVGGLVGAGSGAPITASFWDTETTGQATSIGGSGATGLTTAQARDQGSYAGWNFTTDWYQTADLRPIGLWEAAQPGADGAIPIATLHQLQLVATNPAGRYRLAADLDARATAGTNAADLWGGGGFVPIWGGSTGFAGTFDGRGHVIAGLTINRPTMEAVGLFSVVQSGATVSNVGLVGGSVTGGDTVGGLVGANSGRITQAYVTASVTGGRTVGGFVGSNSGTIAQAYAAGSVTGSSAVGGFVGNNWNGLVTQAYAAGSVTGNTTVGGFAGSNRRTLTQVYATGRVTANNLSGGLVGSSGGTVLASFWDTETTGQAISAGGSGARGLTTAQARDQGSYAGWNFTRDWYQAGDLRPIGRWEAAQPGADGIATVTNLHQLQLVNVNLAGSYALAGDLDAGATAGATASDIWGSGGFVPLGNGMGPFTGRFDGRDHRIAGLTINAPSTSSAGLFGIIGPTGEVRSVGLAGGGVSAAGDAGGLAGTNKGFVTKVFADITARASTYGRAGGLVGSNAGSGALRAVYATGAVSGSDLIGGLVGSNAGIIIQAYATGRVSARSAAGGLVGINSGTIQQAYATGSVTGGTTPDAPVGGLVGTNAGAIRQTYATGSVTGTSTVGGLVGSLRSGATVTASYWDTEATGQATSAGGMGTGLTTAQMLDTPGTAGGFTATATAVGWDFTTVWARPNASAAQSSDGKTHTAELYATSGVVALDASASMTYGDTPPTLAPTVYGSGSVFGNVVSALPSVTSSVTAQSNAGTYAIGLSGGSGTSWGGRTTRFVSPGSVTVDPKTLTVSLTGSVTKTYDGSASASLTGLGLNIVSGRIGQDDVQVAGASASYADAKAGAGKSVTVSGLTLSGAAAGNYTLGTTNQVSAAIGSIDKATLAVSLTGVARKTYDGSASAGLTGLGFDLGSSRIGQDDVQVAGASAVYADAKAGTGKSVTVSGLTLSGVDADNYTLAAPTASAAIGTIDRATLAVSLTGSASKTYDGRTSAGLTGLGLNIVSGRIGQDDVQVAGASASYADAKAGAGKSVTVSGLTLSGADADNYTLAAPTASAAIGTIDKATLTVSLTGVARKTYDGRASAGLTGLGFDLGSSRLGQDDVQVAGASAVYADAKAGTGKSVTVSGLTLSGADAANYTLGSTSQVQGTVGTIDKATLAVSLTGVARKTYDGRTSAGLTGLGFDLGSSRFGQDDVQVAGASASYADAKAGTGKSVTVSGLTLSGADADNYTLAAPTASAAIGTIDRATLAVSLGGAVRKVYDGTVAATVAPGQLSLGGVVGQDVVQASGRAVYADAKAGTGKSVTVSGLTLSGADADNYTLAAPTVSAAIGTIDRATLAVSLTGAARKTYDGSTAATLSAANYALTGLVPGDAVSVAGSAVYADAKAGTGKLVTASGLTLSGADAGNYTLGSATEISAALGTIDRATLAVALTGAVRKTYDGSALAMLGAGNFALAGVVAGDAVTVSGAGGTYDTGNAGTNKLVRASGLSLAGADAGNYVLERTSLSGGIGTIDPATLTASLRGSVSKTYDGSTAAILAAGNYALGGVVGADEVNLVWPANGVYDTKDAGTGKTVSVSGIALAGSAAGNYVLAQTSLSAAIGRILPAPLTVTAGNAAKTYDGRVYSGGNGVSYAGLVGGEDASVLGGSLTYGGSAQGARNAGSYAITPAGLTSGNYAITYAPGTLTVTKAPLTVTAGNAAKTYDGRAYSGGNGVSYAGLVGGEDASLLGGSLTYGGSAQGARNAGTYAITPAGLTSGNYAISYADGTLTVTKAALLVTAGNAAKTYDGRAYSGGNGVSYAGLIGGEDASVLGGSLTYGGSAQGARNAGTYAITPAGLTSGNYAITYAPGTLTVTKAPLTVTANGLSKTYDGQAFSGGNGVSYAGLVGGEEASVLGGSLTYGGSAQGARNAGSYAITPAGLTSGNYAITYAPGTLTVTKTPLTVTANGLSKTYDGQAFSGGNGVSYAGLVGGEDASVLGGSLTYGGSAQGARNAGSYAITPAGLTSGNYAITYAPGTLTVTKAPLTVTAGNDAKTYDGRAYSGGNGVSYAGLVGGEDASVLGGSLTYGGSAQGARNAGSYAITAAGLTSGNYGITFVEGILTVAPRPLTVAADAQSRASGQPNPVLTYAVSGLGLVGGDGLAGQLATPATPDSAPGSYPITQGTLAASPDYALTFLNGTLTVTEAVAAAGSAPPVGSPVTASTVTQVLTLNQSLTPYTPPVFQGAGLTSSQGSPLSDPRFDTPVACLSQAACYITPAAPQTGSPSAGR
>NC_010511.1|WP_012335450.1|6345079_6345697_-|invasion-protein
MSFLSSLPSRGMVLLALALSSGPISGGAAAQPAQGKAAAPAQAAPASVPAEPGLTTATFADWVLRCQRLVDGEKTTRLCEVAQAVQIQGQAAPVAQVAIGRVPGEDGLHVTAVLPVNASFASGVRLAGEDKDGKDGGALDMAWRRCLPGACAAEGPAKDDVLKRWRGPIEASRLTFKDAAGREVAVPISLRGLSQALDALAKERS
>NC_010511.1|WP_012335449.1|6344239_6344755_+|formaldehyde-activating-enzyme
MATINKVLVGEALVGDGNEVAHIDLIIGPRGSAAETAFCNSLTNNKHGFTSLLAVVAPNLPCKPNTLLFNKVTINDARQAVQMFGPAQHAVAKAVQDCVAEGIIPASEADDLYILVGVFIHWEAADDAKIEKYNYEATKLSIQRAIQGKPTAAEVTQQYKTAQHPFAANVS
>NC_010511.1|WP_012335448.1|6343131_6343992_+|triphosphoribosyl-dephospho-CoA-synthase
MEPALQPDAIAAAYRGACRAELAALKPGNVHVFAEGHRMTLADFERSAAFSAGPLAAPGRRVGERVEAAVAATVAAVGQNTNLGIVLLCAPLAAAAERTGPLRDALAAVLAELDGRDAAGVFAAIRRANPGGLGRAARHDVAGGGDPPPLLAAMAEAAGRDRIARAYVTGFEDLFGTGLPALARARAEGLAPPWTATAVHLAFLTGFPDSHIARKFGPERAERVRREAQAALGTVILGESAVPVLLAHDRRLKQDGLNPGTSADLTVATLFLDALMQLRGDQVSAG
>NC_010511.1|WP_012335447.1|6342214_6343132_+|RimK-family-alpha-L-glutamate-ligase
MRIGLAADNGAWHKGRLLAALTRLGAEPVLFSLADVTVETGRPEPLHVPGFGDRLPDGVLLRTIAGGTFEATTMRLGALHALVAAGTVVWNSPAAIERSVDKAMTSLLLARHGVPTPETFVLSRREAAAALVAREAGPGRPLVLKPLFGSQGEGLQLIAAPDELPPEELVGRVYYLQRYIARRDGAWQDYRVFVCDGRAVAGMIRQGDGWITNVHRGGRPLPWTVPPRAAELAEAAAGAVGVAYTGVDLVEDGEGGFLVLEVNSMPAWSGLQQVTGIDIAETVARGFLAAVRARTAPPPRLVAQG
>NC_010511.1|WP_012335446.1|6341044_6342019_+|methenyltetrahydromethanopterin-cyclohydrolase
MSSTTVRPSVNALATPLVEALVADAAKLRLSVSAKSGEARLVDAGAQARGSIEAGRRIAEICLGGLGTVTIAPAGPVAAWPVTVTVHSADPVLACLGSQYAGWSLADEGGSSGFFALGSGPGRAAAAAEHLFEELHYRDHAAQIALVLESASAPPASVVAKVAEAAGVTPDAVTFIYAPTQSLAGATQVVARVLEVALHKAHSVGFDLAKVVDGIGAAPLSPPHPDFIQAMGRTNDAIIYGGRVQLFVEADDAEARGLAEALPSTTSRDHGAPFAEIFARFNGDFYAIDKHLFSPAEVVVTSLLSGTSHRAGRLVPELVERSFA
>NC_010511.1|WP_012335445.1|6339893_6341048_+|ATP-grasp-domain-containing-protein
MPTDPAPPLPRAGGAILIAAQSGRALAAAARRAGLLPYVADLFGDADTRDLAAGYRRVPGRFGTGPRGAALVEALAALAAEAGDPLGLVLGSGFEGSPALMRDLALRHRLIGAAPDTVAALKHPARLAALCARCGIPHPEIALAPVDDPRGWLLKRRGASGGGHVRPAPAGPLPRGAYLQRLVPGTARSLTVLADGRDLRVVADTAQWADPTPARPFRYAGAVDPGGMPAGVREAAAAALAALVAETGLRGLASADLVVEGSDWWLVEVNPRPGATLDILDRREEPLLARHVEAWAGRLGGTLALPVDAAATQICYAPWPIPLVPSVAWPDFVMDRPPAGSRIPAGAPICTVRAEGADARAALSEVRFRADAVRALIAPEGDRS
>NC_010511.1|WP_012335455.1|6365175_6367701_-|EAL-domain-containing-protein
MQARTTDGATSLSRRLWIAILLIGAGLAALSATLVAPAVTAFLRSRHNLAEIAQFARVLEAANRISAERGPANVAMSQDPAGNAAALTRLREFREATDRALAQLHGPDDPDGLTGPARRLPADLIDAAQARLRAARREVDEIARMPAAARGADQIRAAVGAMIAVVDQFQDVVTWEVRTLRELDPALAGQAMVARAVSDLREHGGRIASFIVPALAVRAPLGEVHLAEAVETRGRLREIWQLLQGQIPAALDPLMREVESRFLGEGLGTVEAVIAEGRGPSGRYSLDAQTLTARYVPTLKPLEDLRTAFLARMNAASARERDGARDALAAAGLVTLAALALIGGLLGSLRASILRPLLDAREAIVALAGGVDPAPVRAPMRVREIALLFDALLVLQKRLQERANLMQTLRRQAETDGLTGLYNRRALTRDLATLDARPAGGLAGLLLIDVDGFKRVNDSFGHAVGDVLLRLVGQRLQGDVGGSGLVARIGADEFAVLLPDLAEPAEGERTADRILGGLAEPFRVAEQIFHLDASIGVAVAPHGQRGADDLLARADMALHEAKRAGQHCRRVFRPEMRRSLLAWTACQQEMPRALAEGEFVLFYQPQLRLRDRTIAGAEALIRWRHPERGLLAPADFLAPLESSRAAEDVGRFVLRTACAEAAGWRRRGLGELRVAVNLFSRQFLSRDLVEEVRAALAEAALPASALELEITETIILQHDDALIPPLRALRDMGVGLAFDDYGTGYASLSLLKRFPLTRLKIDRSFVRGIPDSAQDLAIVRSVVALGRSFGLEVTAEGIETPAMLRCVTAEGCQEGQGYLFGQPMAADLFAAQCWAEGRRTA
>NC_010511.1|WP_012335456.1|6367924_6368146_-|hypothetical-protein
MRFIRTLRAMWLLRKANRDLEEARTLREAAEACRARADQRLARAGRLLAGTPLRQDSQGHPLVVALVRRCIAA
>NC_010511.1|WP_012335457.1|6370586_6371378_+|calcium-transporter-ChaC
MTDRPVLTAALIARAHPDPVPDDAAAMPLLSEAETEALLAAALAAKPGPPDEIWLFAYGALMWRPEFPFAERRAAGLPGWHRRFCLWQWRFRGTRDNPGVMLALDRGGRCRGLAYRLAGPDPLAALRPVWHREMRGRGYAARWLAARTEAGTVPALAFVANRAGERYAGRLGEEAIAARIAAACGHLGPNAEYLLNTAASCAALGLRDRHLERLQALVAARLEAAARARAGAADMAAGAARRPPARRPPATRPPASPEPEPEA
>NC_010511.1|WP_012335458.1|6371780_6371993_+|hypothetical-protein
MTLFSGTARAAAVADRRDQSIAVALILLLALVFAPAIGLHVAVSTFGVGAPAPTPEGVAAAPAEAKPSRG
>NC_010511.1|WP_018263818.1|6372293_6372473_+|hypothetical-protein
MTATDPAKDSAKPGDKAPPGTPGTGENICPRCHGSGRVEGTSCPDCAGTGKVTEPIGGA
>NC_010511.1|WP_012335461.1|6372681_6373428_+|hypothetical-protein
MAGERRSKAAEWREARNAVSRARLEKALPAIFPPLVLRHALSRPFVPPTPRLAVESYWRGHVIRADRLARALAARSGHPEGWTWRLGKEEGLGASFRLPPAPFREPAFARGRGHCCICGQPVFRFGWHADLWGAGAPNRNAGWHAACVTAWKFWIAASDHAKVLKARQRHRCPETGKRLLRSAEVDHRVPLYQVWREHRDAPWPRLLGYWGVPNLQVVNRAAHVGKCAAEAGERAAHRRLAAAQRGTM
>NC_010511.1|WP_012335462.1|6373409_6373688_-|hypothetical-protein
MTMAGLIRILCLGAAGLLPLSAQAGPRRLPPDIDATGTVGGRAPWSQPWEYDSGSDNDHHPERPYYQQGRGQQTGGPARNLLPDDGLHIVPR
>NC_010511.1|WP_012335463.1|6373892_6374201_+|hypothetical-protein
MIRTATLITALAALASYALVPSGTGAEAHVAPAAKRFTDKRFTERLPVASFRPEPQDIALFSLAGAQRTAARPCSTWPYEGARCVAEAPEPGVARVAGLARR
>NC_010511.1|WP_012335464.1|6374375_6374681_+|hypothetical-protein
MLKLARILGLLLLPGTALARDLPHRVPAPALRCGQVLALLNQRGEAIVDTGPFTYERLVRDIGFCPIEQTTEPFFGPSADAGRCFLGYRCKDRMSEGRRGD
>NC_010511.1|WP_012335465.1|6374694_6375759_-|aromatic-ring-hydroxylating-dioxygenase-subunit-alpha
MGPGPDPQDSMTGDPIRRPLDDVWYCVGESRRFREGRLCAVTLGEEAIVVGRAAGGGLFALRDRCPHRGMALSAGRLVEGRLVCPFHGWEFRPDGQCAAIPALAARDESDFRTVRLPRFSVREASGLVWIAAGEPRPDAPPIPEVEFPYAGMLVETLEVEASFDLVALSFVDPAHVAYVHDLWWWRTSKTLREKEKHFAPSPFGFTMTSHRAKSASAVYRLLGAVPEVEIEFRLPGVRLERIRAGEKRIANYTFATPLGPGRTALVNAMYWNLPLLNLLRPLARPLMRQFLGQDRDVLQVAQKGLDRKPAMVLIGESDVQSQWYFSLKREFLRAREAGAAFANPLAPRLLRWRS

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Crispr_ID: NC_010511_36

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_010511_36

6830727-6830833

Orphan

Consensus_repeat	Method
GCCCGCGCGGCGCCTGAGCGAAGCCGACATCCGCATGGC	CRISPRCasFinder

1 spacers

The CRISPR arrays of NC_010511_36

>merge|NC_010511|36|6830727-6830833|CRISPRCasFinder
GCCCGCGCGGCGCCTGAGCGAAGCCGACATCCGCATGGCGAAGCCATCAACCGGATGTCGGATGACACGCCCGCGCGGCGCCTGAGCGAGGCCGACATCCGCATGGC

>NC_010511|36|36|6830727-6830833|CRISPRCasFinder
GCCCGCGCGGCGCCTGAGCGAAGCCGACATCCGCATGGC	GAAGCCATCAACCGGATGTCGGATGACAC
GCCCGCGCGGCGCCTGAGCGAGGCCGACATCCGCATGGC

Protein	Signature genes	Signature genes Name	Protein_function
NC_010511.1\|WP_012335847.1\|6819912_6820116_+\|hypothetical-protein	unknown	unknown	unknown
NC_010511.1\|WP_012335855.1\|6826383_6827412_+\|chemotaxis-protein-CheB	unknown	unknown	gnl\|CDD\|319752
NC_010511.1\|WP_012335848.1\|6820234_6820393_+\|hypothetical-protein	unknown	unknown	unknown
NC_010511.1\|WP_012335865.1\|6838776_6839949_-\|4-hydroxybenzoate-3-monooxygenase	unknown	unknown	gnl\|CDD\|236198
NC_010511.1\|WP_012335849.1\|6820490_6821387_+\|LysR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|176138
NC_010511.1\|WP_012335862.1\|6836935_6837946_+\|TIGR01620-family-protein	unknown	unknown	gnl\|CDD\|235449
NC_010511.1\|WP_012335850.1\|6821524_6822880_+\|glucarate-dehydratase	unknown	unknown	gnl\|CDD\|211799
NC_010511.1\|WP_012335864.1\|6838261_6838543_-\|plasmid-maintenance-system-killer-protein	unknown	unknown	gnl\|CDD\|226079
NC_010511.1\|WP_012335854.1\|6825614_6826358_+\|Crp/Fnr-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|223736
NC_010511.1\|WP_012335859.1\|6833224_6833749_+\|histidine-phosphatase-family-protein	unknown	unknown	gnl\|CDD\|224973
NC_010511.1\|WP_012335866.1\|6840111_6840999_+\|helix-turn-helix-domain-containing-protein	unknown	unknown	gnl\|CDD\|380403
NC_010511.1\|WP_012335860.1\|6834017_6835373_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|235906
NC_010511.1\|WP_012335851.1\|6822901_6823672_+\|HpcH/HpaI-aldolase/citrate-lyase-family-protein	unknown	unknown	gnl\|CDD\|226356
NC_010511.1\|WP_012335856.1\|6827505_6830691_+\|PAS-domain-containing-protein	unknown	unknown	gnl\|CDD\|224271
NC_010511.1\|WP_012335857.1\|6831132_6831666_-\|response-regulator	unknown	unknown	gnl\|CDD\|333815
NC_010511.1\|WP_012335852.1\|6823689_6824571_+\|2-hydroxy-3-oxopropionate-reductase	unknown	unknown	gnl\|CDD\|185019
NC_010511.1\|WP_012335861.1\|6835493_6836939_+\|YcjX-family-protein	unknown	unknown	gnl\|CDD\|367902
NC_010511.1\|WP_012335858.1\|6832365_6833211_+\|MoxR-family-ATPase	unknown	unknown	gnl\|CDD\|223786
NC_010511.1\|WP_018263550.1\|6837956_6838247_-\|HigA-family-addiction-module-antidote-protein	unknown	unknown	gnl\|CDD\|274228
NC_010511.1\|WP_012335853.1\|6824725_6824974_-\|hypothetical-protein	unknown	unknown	unknown

Protein	Function_ID	Function_description	E-value
NC_010511.1\|WP_012335851.1\|6822901_6823672_+\|HpcH/HpaI-aldolase/citrate-lyase-family-protein	gnl\|CDD\|226356	COG3836, HpcH, 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase [Carbohydrate transport and metabolism].	1.38979e-113
NC_010511.1\|WP_012335865.1\|6838776_6839949_-\|4-hydroxybenzoate-3-monooxygenase	gnl\|CDD\|236198	PRK08243, PRK08243, 4-hydroxybenzoate 3-monooxygenase; Validated.	0
NC_010511.1\|WP_012335849.1\|6820490_6821387_+\|LysR-family-transcriptional-regulator	gnl\|CDD\|176138	cd08447, PBP2_LTTR_aromatics_like_1, The C-terminal substrate binding domain of an uncharacterized LysR-type transcriptional regulator similar to regulators involved in the catabolism of aromatic compounds, contains type 2 periplasmic binding fold. This CD represents the substrate binding domain of an uncharacterized LysR-type regulator similar to CbnR which is involved in the regulation of chlorocatechol breakdown. The transcription of the genes encoding enzymes involved in such degradation is regulated and expression of these enzymes is enhanced by inducers, which are either an intermediate in the metabolic pathway or compounds to be degraded. This substrate-binding domain shows significant homology to the type 2 periplasmic binding proteins (PBP2), which are responsible for the uptake of a variety of substrates such as phosphate, sulfate, polysaccharides, lysine/arginine/ornithine, and histidine. The PBP2 bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap. After binding their specific ligand with high affinity, they can interact with a cognate membrane transport complex comprised of two integral membrane domains and two cytoplasmically located ATPase domains. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis.	9.30268e-87
NC_010511.1\|WP_012335862.1\|6836935_6837946_+\|TIGR01620-family-protein	gnl\|CDD\|235449	PRK05415, PRK05415, hypothetical protein; Provisional.	9.0827e-88
NC_010511.1\|WP_012335850.1\|6821524_6822880_+\|glucarate-dehydratase	gnl\|CDD\|211799	TIGR03247, glucar-dehydr, glucarate dehydratase. Glucarate dehydratase converts D-glucarate (and L-idarate, a stereoisomer) to 5-dehydro-4-deoxyglucarate which is subsequently acted on by GarL, tartronate semialdehyde reductase and glycerate kinase (GenProp0716). The E. coli enzyme has been well-characterized.	0
NC_010511.1\|WP_012335864.1\|6838261_6838543_-\|plasmid-maintenance-system-killer-protein	gnl\|CDD\|226079	COG3549, HigB, Plasmid maintenance system killer protein [General function prediction only].	2.94291e-27
NC_010511.1\|WP_012335854.1\|6825614_6826358_+\|Crp/Fnr-family-transcriptional-regulator	gnl\|CDD\|223736	COG0664, Crp, cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms].	1.05103e-33
NC_010511.1\|WP_012335859.1\|6833224_6833749_+\|histidine-phosphatase-family-protein	gnl\|CDD\|224973	COG2062, SixA, Phosphohistidine phosphatase SixA [Signal transduction mechanisms].	6.78029e-42
NC_010511.1\|WP_012335866.1\|6840111_6840999_+\|helix-turn-helix-domain-containing-protein	gnl\|CDD\|380403	cd06999, cupin_HpaA-like_N, AraC/XylS family transcriptional regulators similar to HpaA, N-terminal cupin domain. Members of this family contain an N-terminal cupin domain and a C-terminal AraC/XylS family helix-turn-helix (HTH) DNA-binding domain, similar to Escherichia coli 4-hydroxyphenylacetate catabolism regulatory protein HpaA (also known as 4HPA). HpaA is encoded by the hpaA gene which is located upstream of hpaBC. It is activated by 4-HPA, 3-HPA and phenylacetate, and represents a member of the AraC/XylS family of regulators that recognizes aromatic effectors. Proteins in this family belong to the cupin superfamily with a conserved "jelly roll-like" beta-barrel fold capable of homodimerization.	4.94252e-40
NC_010511.1\|WP_012335860.1\|6834017_6835373_+\|hypothetical-protein	gnl\|CDD\|235906	PRK07003, PRK07003, DNA polymerase III subunit gamma/tau.	2.08883e-05
NC_010511.1\|WP_012335855.1\|6826383_6827412_+\|chemotaxis-protein-CheB	gnl\|CDD\|319752	cd16433, CheB, Chemotaxis response regulator protein-glutamate methylesterase, CheB. This family contains the methylesterase CheB (EC 3.1.1.61; also known as CheB methylesterase, chemotaxis-specific methylesterase, methyl-accepting chemotaxis protein methyl-esterase, or protein methyl-esterase) domain, a phosphorylation-activated response regulator involved in reversible modification of bacterial chemotaxis receptors. Signaling output of the chemotaxis receptors is modulated by CheB and methyltransferase CheR by controlling the level of receptor methylation. cheR and cheB have a strong preference to occur in the same operon, and a subgroup contains multidomain proteins with CheB-CheR fusions. Reversible methylation of transmembrane chemoreceptors plays an important role in ligand-dependent signaling and cellular adaptation in bacterial chemotaxis. Phosphorylated CheB catalyzes deamidation of specific glutamine residues in the cytoplasmic region of the chemoreceptors and demethylation of specific methyl glutamate residues introduced into the chemoreceptors by CheR.	4.18449e-82
NC_010511.1\|WP_012335856.1\|6827505_6830691_+\|PAS-domain-containing-protein	gnl\|CDD\|224271	COG1352, CheR, Methylase of chemotaxis methyl-accepting proteins [Cell motility and secretion / Signal transduction mechanisms].	6.14031e-81
NC_010511.1\|WP_012335857.1\|6831132_6831666_-\|response-regulator	gnl\|CDD\|333815	pfam00072, Response_reg, Response regulator receiver domain. This domain receives the signal from the sensor partner in bacterial two-component systems. It is usually found N-terminal to a DNA binding effector domain.	4.52763e-18
NC_010511.1\|WP_012335852.1\|6823689_6824571_+\|2-hydroxy-3-oxopropionate-reductase	gnl\|CDD\|185019	PRK15059, PRK15059, 2-hydroxy-3-oxopropionate reductase.	3.44931e-117
NC_010511.1\|WP_012335861.1\|6835493_6836939_+\|YcjX-family-protein	gnl\|CDD\|367902	pfam04317, DUF463, YcjX-like family, DUF463. These proteins possess a P-loop motif.	0
NC_010511.1\|WP_012335858.1\|6832365_6833211_+\|MoxR-family-ATPase	gnl\|CDD\|223786	COG0714, COG0714, MoxR-like ATPases [General function prediction only].	7.75641e-45
NC_010511.1\|WP_018263550.1\|6837956_6838247_-\|HigA-family-addiction-module-antidote-protein	gnl\|CDD\|274228	TIGR02607, Virulence-associated_protein_I, addiction module antidote protein, HigA family. Members of this family form a distinct clade within the larger family HTH_3 of helix-turn-helix proteins, described by pfam01381. Members of this clade are strictly bacterial and nearly always shorter than 110 amino acids. This family includes the characterized member HigA, without which the killer protein HigB cannot be cloned. The hig (host inhibition of growth) system is noted to be unusual in that killer protein is uncoded by the upstream member of the gene pair. [Regulatory functions, DNA interactions, Regulatory functions, Protein interactions, Mobile and extrachromosomal element functions, Other].	2.36647e-33

>NC_010511.1|WP_012335856.1|6827505_6830691_+|PAS-domain-containing-protein
MEADTIASGADDPVGVVLAVSASAASPASLERLLAGPLPSAQVATILILQHREILDEARLRLALGLSGRGLTAVEDGLPLAGGRLYLPAPGAIATIERGRFRTRPAEQAPGERGVIDSLLVSLAREENRRAVVVALAGTDGDGTLGVKMIKESGGLALAEETAEARADDLAASNSPAALADAILPLDDLADRLRAYVAQLLREDEAMPEGALPSEEIAGALTAVATILRNKTGHDFHGYKPGTFLRRVQRRMQVVQAESLAAYVEILRAKPDEAQGLFNDLLIGVTQFFRDPGEFDLLEREVVPALFSGKRRSDQLRVWVIGCSTGEEAYSIAILLREQLADRDEVPQIQIFATDLDGRALAAARAGRYADDIAAEMSPERLARWFVREGDTYCVVKEVREMCIFSQHSIVKDAPFSRLDLISCRNLLIYLDAELQSRVVPLFHFALRPGGFLFLGNSENVSRHTGLFAPIEGRSRIFRRLETGTRTLPDFPFAAVDRRLAAPAVPPERPRAAEATLTRRAERFAERFAPAYVIVDESYTVLHFSGRTGRYIDPAGGAASLNLLQLVHPDLRLDLRAALTRAAEHGATVQLDGLRIGLNGHRLVVDLVVEPVQEAPGAGLSFVVLFKDGAMLASDEDGAPAPSAQTEHAQRLEAELRTTKDRLQATIEELESTNEELKSSNEEYQSLNEELQSANEELETSKEELQSVNEELTTVNGELGHRVNELTRATSDLKNFLESTQIATVFLDNDLRVTNSTPAVSEVFHLVESDVGRPIAHIKPRVAYDELQEDARRVLRTLGTVEREIVNPATGARYMVRVLPYRSVDNFIAGVVVTFVDITARLRAEEALRASEGQAKLLLAELQHRVRNTLAVMRSVVRRTALSSDSVEDYAAHLEGRIDAFARVQSAVTRDPAAGIDLEQLVSHELLAHAAHEGEQVRRIEGPPVRLRPKAAETLALAIHELATNAVKHGALTAPSGRVTVTWRIEDRSAPEPLLTLAWIETGVTLSGDPPSRRGFGTELIERTLSYELGGSAALSFRPEGMQCHIVLPANDRILVQRERE
>NC_010511.1|WP_012335855.1|6826383_6827412_+|chemotaxis-protein-CheB
MTNRDIIVIGGSAGATVPLKALLRALPADLPAAVLVVLHIPARSLGLLATVTSAASRLPVETAQDGMAIRPGHIYLGVPDRHLLLVDGVIRLGRGPRENMVRPAIDPLFRSAAIAYGPRVIGVVLSGLLNDGAAGLDAIKACGGLALVQDPADAVADEMPLAALAAAAVDLAVPGARLGDVLSDLARETPGPRLPVPPEIRIEVDIAAGERVGSGVLRQIADPAPLTCPHCCGVLSEVRGSKPVRFRCQVGHALTAEALAKEQEAAVDEAMRVALRIVEERADLVARMAEDGRRSGRRAVAEMYEARAAEYRGYGETIRRAILSAMPQPGAADPGDGNGEAG
>NC_010511.1|WP_012335854.1|6825614_6826358_+|Crp/Fnr-family-transcriptional-regulator
MPTYLIRKLEQFTRLSSDDKQALERAASGKLRRFSSREDIIREGEAPRRVNLILDGWACRYKVLEDGRRQIAAFLLPGDLCDIRMFILKHMDHSVGTLSPATVVEIPRETILDLTDNFPRLSRALWWYSLVEEATQREWTTNLGQRDALERMAHLLCEVFIRLRGIGLTDGTSCELPVTQAELADATGLSTVHVNRTLQDLRARGLVILRGKTLTVPDLEALQDAALFSPNYLHLDCEGQELDANDS
>NC_010511.1|WP_012335853.1|6824725_6824974_-|hypothetical-protein
MKLKPFLAAGALLVAAAPAFAQGGSPYNASGSQAGGPRAGIERRYGLTEGDRAGYDAIYPRERAPFAVVPRGQAYPGFLVEE
>NC_010511.1|WP_012335852.1|6823689_6824571_+|2-hydroxy-3-oxopropionate-reductase
MDVGFIGLGIMGAPMAGHLIAGGHSLHLKSRRRVPEALVAAGGRPCASAAEVAARAEVVILMVPDTPDVEAVLFGAGGVAEGLRPGCVVVDMSSISPIATRDFAARIEAAGGHYVDAPVSGGEVGAKNAALSIMVGGSEEAVARVRPLLDLMGKSVTHVGGTGAGQVAKVANQIIVALTIEAVAEGLLFASKAGADPAKVRQAITGGLATSRILELHGERMITRRFDPGFRIALHQKDLNLALEGARSLGLSLPGTALAQQLFSACAANGAGGQDHSALVRALEILGNHEVAG
>NC_010511.1|WP_012335851.1|6822901_6823672_+|HpcH/HpaI-aldolase/citrate-lyase-family-protein
MDILTNRFKAGLRARRQQVGLWCSLASAISTEIVAGSGFDWLLLDMEHSPNDLRDIYGQLQAMAEGGAAPVVRVPSDDPIAIKRVLDAGAQSLMIPNVDGAAQARAVVAATRYAPEGIRGFSQAPRAARFGRIPDYHARSNGEIAVLVQVESRRALDNLEEIAAVEGVDGLFVGPGDLSASLGHLGQQNHPEVVAEIERTIGRIVATGKAAGILTANEELAARYARAGTTFTAIGSDLGLLARGSEALAARFRAGL
>NC_010511.1|WP_012335850.1|6821524_6822880_+|glucarate-dehydratase
METAAGPAQGLSRTPTIAAMRVVPVAGRDSMLLNLSGAHGPFFTRNLVVLTDSTGATGLGEVPGGERIRQTLEDARGLVLGQPLGAWNRVLAAMRARFADRDAGGRGLQTFDLRVAIHAVTAVESAFLDLLGQFLGVPVAALLGEGQQRDAVEMLGYLFYVGDRRRTNLAYREPEARDGWLRLRDEEALTPDAVVRLAEAAHERYGFNDFKLKGGVLAGEREIEAVTALAKRFPQARVTLDPNGAWSLEEAIRLCRGRGDVLAYAEDPCGAENGFSGREVMAEFRRATGLPTATNMIATDWRQMVHALQLGAVDIPLADPHFWTLAGAVRVAQTCRDHGLTWGSHSNNHFDVSLAMFTHAAAAAPGKVTAIDTHWIWQDGQRLTREPPEIRGGLVRVPERPGLGVALDWEAVEAAHALYERHGLGARDDAAAMQFLIPGWTFDPKTPCLVR
>NC_010511.1|WP_012335849.1|6820490_6821387_+|LysR-family-transcriptional-regulator
MLEFSQIRCFVAVAEELHFGRAAARLSMTQPPLSRQIQVLERILDVQLLERSSRSVRLTAAGRSFLPEAQRILRLSEAAAQVTRQVAAGRAGTLRLSFTAASAYAYLPDLVIACRAALPEVSLALREMVTKDQIEDLLASRLDAALVRPPVTHPELDSVRARAEPLVAALPSDHPLAARPALALADLDRQPLIGYAPHEARYFYDLVAGLCAEARVQPHAVQQLAQIHSILALVRAGLGIALVPHSAERLRLDGVAYRPLALPEPRPVELVLAWRRDHDNPLIGQLIRLVAERAEAAP
>NC_010511.1|WP_012335848.1|6820234_6820393_+|hypothetical-protein
MHRLGRARGSIAAARLERAAMREGRLFLEGCGAVWTACLGWVALRTARYILD
>NC_010511.1|WP_012335847.1|6819912_6820116_+|hypothetical-protein
MITRIITSALRKTIRPEDAPEADDVVEPDLAFPPMVPVVPPAAQNDDPDQPLLGEIERDLRAAGYLS
>NC_010511.1|WP_012335857.1|6831132_6831666_-|response-regulator
MAHGVGRGLQDLFGAPMQEALPERLRDLVALLVARDAVGRREEGRRGPAGEPTQLVLVVEDDPAVRDLAVALLRDTVLDVAACGSGEEAVALLKQRGTEVAMVFTDVRLPGGMDGIALARAVSQLWPGVRVVVTSGFADARIAGLPQGAVYMPKPWRALDVLAQVDHAVRHPDPPVA
>NC_010511.1|WP_012335858.1|6832365_6833211_+|MoxR-family-ATPase
MRFSGTDTYVASPDLAVAVNAAVTLERPLLIKGEPGTGKTVLAEEVARALSAPLLTWHVKSTTKAQQGLYEYDAVSRLRDSQLGDPRVSDIRHYIRRGKLWEAFTAPERPVLLIDEIDKADIEFPNDLLLELDRMEFHVYETGETVRAARRPIVIITSNNEKELPDAFLRRCFFHYIKFPDPETLQAIVAVHYPGLKQRLVEEALRIFFEVREAPGLKKKPSTSELLDWLKLLMAEDIGPESLRERDPRKLIPPLHGALLKNEQDVALFEKLAFLSRRDGR
>NC_010511.1|WP_012335859.1|6833224_6833749_+|histidine-phosphatase-family-protein
MRRLILLRHAKSDWPDGVPDSDRPLSRRGREAAPRMAAYLAEEGLRPDHALVSPARRTQETWSLVAPALPGAAQETVPALYEASAKRLLDVVRGADDAVATLLLLGHNPGLQEFGQLLLADEDRDGLRALSRKFPTAAVAVIDLAVGAWAEVAPHSGTLERFITPKALGAGEDD
>NC_010511.1|WP_012335860.1|6834017_6835373_+|hypothetical-protein
MILLPLLALATALGPGADRAAALAREGLAAADAAGRLALARTALAVPEAGPALYRPEARAVSNWREEARFSLRPLSLALVAFAAPADPAFVARCVKLNNYWCIKRAGWDGEIGADAEGHTGFASAEQGADAAVALLRRYYTVLGRRSALAIVRRWAPAECAAPAAALARPPGPAGGGAARRPAAVQAAAIPASPALTALAPRGIGRTLRARFLARHGRGGLARPAPRAAPRAVARAAPGLPPGAVARAAPGGPALRIQPWSALARLGGRTRPPVRPNPPRPAASVPTIATGIGAAPEPAAPVTPARLLDGDRLLAEAAALPSLTSLSSVAALPPALRPPAPLCGSDEARIQAYARRIAESVGLGAGDDLGLFDAQGSATARLAPVLLAMSAVELGSLRANPALVAEAIARAESSRARLSAQAQSAAQAQPAAPVRPAARAEAEGLARPHQP
>NC_010511.1|WP_012335861.1|6835493_6836939_+|YcjX-family-protein
MPPLLSFVERAGSAARALAEASSDLLVQPTLRLGVTGLARSGKTVFTAALVHQLSGLNPLPALRASQEGRLRRARLVPQPDDDVPRFPYEEHLAALTEERRWPRSTDRISQLRLAIAYERAAGWRPGPASLMVDIVDYPGEWLLDLALIEQTYEGWSRETIAAAQRPGRAALAAPWLDLLRGLDPNQPLDEVVAERASDAFKAYLAAVRAGPEAVATTPPGRFLMPGDLAGSPALTFAPLLLTGPTGPDSLGGLMERRFEAYKGRVVTPFFREHFQRIDRQIVLVDVLAAVDAGAAALAELEDALDRVLMSLRIGRNSVLSRLFAPRADRILFAATKADHLHHSSHDRLDALLRLLVARSLRRTEAAGARVGTVALASVRATRETLVHEGPHTLQAVAGTPEAGEAIGDDVFDGETEAAIFPGELPERPEAVLEGAVEPGSLRFPRFRPPRVPADALGRPGRLPQIRLDRALQFLIGDRLA
>NC_010511.1|WP_012335862.1|6836935_6837946_+|TIGR01620-family-protein
MSLPPKPRAFRLPPEPGPPGTETPLAEGVRVVEQPFEIVDAADGVPVPVAPRAGPPWATLLLSALGGLASLGIGLAVERLIADLFAAAPWLGAVALALLALAAVALLALVWRELAGVLRERRIEAIREAALAALASRDHTAAKAVVREVGTLYAERPGLAAARGRLDAVADAILDVEDRLGIAEHELLGPLDRLAKAAVADAAKQVSAVTALSPRAIVDVAFVVFAAVRLLRRVATIYGGRPGLFGFLRLARAAFAHLAVTGGVAVGDSLVQQVLGLGLAARVSAKLGEGVLNGLMTARFGLAALAVCRPLPFLREPAPRIGDVAGELIRTGEAEG
>NC_010511.1|WP_018263550.1|6837956_6838247_-|HigA-family-addiction-module-antidote-protein
MPRIRTHPGEVLLEDFMKPFGLSARQLAEAIRVPHNRIGDILRERRSITADTALRLGRYFGTTAQFWVNLQTAHDLSKAAATHDYETIRPREAAPT
>NC_010511.1|WP_012335864.1|6838261_6838543_-|plasmid-maintenance-system-killer-protein
MIQSFADKHARALHEDGICHPRWRAFERIALRKLDALDAAVDLDDLRSPPGNRLEPLQGDRAGQHSIRINDQWRICFRWTDLGPEEVAIVDYH
>NC_010511.1|WP_012335865.1|6838776_6839949_-|4-hydroxybenzoate-3-monooxygenase
MRCQVAIIGAGPAGMFLAHLLARAGIDAVVLERRTRDYVEGRVRAGVLEQGTVAVLEALGLDGRLKAEGLVHTGTNLAYDGEIFRIDMAALTGGAVTVYGQQEVMRDLFDAAEARGLRIVFEAEDVALRDVAGERPRVEYRCGGAAHSLSCDFIAGCDGFHGVGRAAIPPDVLRVFERVYPFGWLGILAELPPVNHELIYANHRNGFALASMRSPTRSRYYVQVGLDERIEDWPDARFWDELALRLGPEAASGLVRGPSFEKSIAPLRSVVAEPMRHGRLFLAGDAAHIVPPTGAKGMNLAVSDVAMLGEALVAHYREGDASGLDGYSARALARVWKAERFSWWFTGLTHRFPDMDPFARRMQVAELAYIRGSVAAQTVLAENYVGLPMG
>NC_010511.1|WP_012335866.1|6840111_6840999_+|helix-turn-helix-domain-containing-protein
MPSLPAQAPAVPHFFLYGEAPRDADDRFLHLEALDDRSRPNRWRIRPHVHAGLHQILHLPRGGGVMRAEAERIAFAGPCFLLVPAGTAHGFRFAHETVGTVLTLSDRYLRDLARREPDLAGLFRAPAALAETAPSGAGECLAELARELTWAAPGRRAALEGHLLVLLVAVLRHARAAQGPPAPPGPQAVLVARFREAVEARHREERPLDAYARDLGVTPARLRAACRAVTGESPGRIVRDRRLLEAKRTLLYSDLSVAEVAYSLGFSDPAYFSRFFAQGTGEPPRAFRARRGATG

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity
NC_010511_1	1.1\|288577\|26\|NC_010511\|CRISPRCasFinder	288577-288602	26	NC_010511.1	5125122-5125147	0	1.0
NC_010511_17	17.1\|3091259\|31\|NC_010511\|CRISPRCasFinder	3091259-3091289	31	NC_010511.1	5207191-5207221	0	1.0
NC_010511_19	19.1\|3439741\|45\|NC_010511\|CRISPRCasFinder	3439741-3439785	45	NC_010511.1	4201622-4201666	0	1.0
NC_010511_19	19.1\|3439741\|45\|NC_010511\|CRISPRCasFinder	3439741-3439785	45	NC_010511.1	6308360-6308404	0	1.0
NC_010511_22	22.1\|3951416\|26\|NC_010511\|CRISPRCasFinder	3951416-3951441	26	NC_010511.1	4106327-4106352	0	1.0
NC_010511_24	24.1\|4168034\|33\|NC_010511\|CRISPRCasFinder	4168034-4168066	33	NC_010511.1	5125007-5125039	0	1.0
NC_010511_25	25.1\|4213563\|42\|NC_010511\|CRISPRCasFinder	4213563-4213604	42	NC_010511.1	4201625-4201666	0	1.0
NC_010511_25	25.1\|4213563\|42\|NC_010511\|CRISPRCasFinder	4213563-4213604	42	NC_010511.1	6308360-6308401	0	1.0
NC_010511_29	29.1\|4808291\|44\|NC_010511\|CRISPRCasFinder	4808291-4808334	44	NC_010511.1	3156598-3156641	0	1.0
NC_010511_1	1.1\|288577\|26\|NC_010511\|CRISPRCasFinder	288577-288602	26	NC_010511.1	5207196-5207221	1	0.962
NC_010511_1	1.1\|288577\|26\|NC_010511\|CRISPRCasFinder	288577-288602	26	NC_010511.1	4106371-4106396	1	0.962
NC_010511_1	1.1\|288577\|26\|NC_010511\|CRISPRCasFinder	288577-288602	26	NC_010511.1	5125054-5125079	1	0.962
NC_010511_17	17.1\|3091259\|31\|NC_010511\|CRISPRCasFinder	3091259-3091289	31	NC_010511.1	5125054-5125084	1	0.968
NC_010511_19	19.1\|3439741\|45\|NC_010511\|CRISPRCasFinder	3439741-3439785	45	NC_010511.1	6308429-6308473	1	0.978
NC_010511_20	20.1\|3661604\|29\|NC_010511\|CRISPRCasFinder	3661604-3661632	29	NC_010511.1	6742392-6742420	1	0.966
NC_010511_22	22.1\|3951416\|26\|NC_010511\|CRISPRCasFinder	3951416-3951441	26	NC_010511.1	69415-69440	1	0.962
NC_010511_22	22.1\|3951416\|26\|NC_010511\|CRISPRCasFinder	3951416-3951441	26	NC_010511.1	567995-568020	1	0.962
NC_010511_22	22.1\|3951416\|26\|NC_010511\|CRISPRCasFinder	3951416-3951441	26	NC_010511.1	1140882-1140907	1	0.962
NC_010511_22	22.1\|3951416\|26\|NC_010511\|CRISPRCasFinder	3951416-3951441	26	NC_010511.1	2582405-2582430	1	0.962
NC_010511_22	22.1\|3951416\|26\|NC_010511\|CRISPRCasFinder	3951416-3951441	26	NC_010511.1	3820664-3820689	1	0.962
NC_010511_22	22.1\|3951416\|26\|NC_010511\|CRISPRCasFinder	3951416-3951441	26	NC_010511.1	4213608-4213633	1	0.962
NC_010511_22	22.1\|3951416\|26\|NC_010511\|CRISPRCasFinder	3951416-3951441	26	NC_010511.1	5099469-5099494	1	0.962
NC_010511_22	22.1\|3951416\|26\|NC_010511\|CRISPRCasFinder	3951416-3951441	26	NC_010511.1	7489610-7489635	1	0.962
NC_010511_23	23.1\|3970298\|41\|NC_010511\|CRISPRCasFinder	3970298-3970338	41	NC_010511.1	2067885-2067925	1	0.976
NC_010511_24	24.1\|4168034\|33\|NC_010511\|CRISPRCasFinder	4168034-4168066	33	NC_010511.1	4094251-4094283	1	0.97
NC_010511_25	25.1\|4213563\|42\|NC_010511\|CRISPRCasFinder	4213563-4213604	42	NC_010511.1	217512-217553	1	0.976
NC_010511_25	25.1\|4213563\|42\|NC_010511\|CRISPRCasFinder	4213563-4213604	42	NC_010511.1	3902323-3902364	1	0.976
NC_010511_25	25.1\|4213563\|42\|NC_010511\|CRISPRCasFinder	4213563-4213604	42	NC_010511.1	4240522-4240563	1	0.976
NC_010511_25	25.1\|4213563\|42\|NC_010511\|CRISPRCasFinder	4213563-4213604	42	NC_010511.1	6308429-6308470	1	0.976
NC_010511_25	25.1\|4213563\|42\|NC_010511\|CRISPRCasFinder	4213563-4213604	42	NC_010511.1	6763089-6763130	1	0.976
NC_010511_26	26.1\|4322290\|25\|NC_010511\|CRISPRCasFinder	4322290-4322314	25	NC_010511.1	6184467-6184491	1	0.96
NC_010511_27	27.1\|4397367\|43\|NC_010511\|CRISPRCasFinder	4397367-4397409	43	NC_010511.1	3902318-3902360	1	0.977
NC_010511_27	27.1\|4397367\|43\|NC_010511\|CRISPRCasFinder	4397367-4397409	43	NC_010511.1	6763093-6763135	1	0.977
NC_010511_29	29.1\|4808291\|44\|NC_010511\|CRISPRCasFinder	4808291-4808334	44	NC_010511.1	1811107-1811150	1	0.977
NC_010511_29	29.1\|4808291\|44\|NC_010511\|CRISPRCasFinder	4808291-4808334	44	NC_010511.1	3283937-3283980	1	0.977
NC_010511_29	29.1\|4808291\|44\|NC_010511\|CRISPRCasFinder	4808291-4808334	44	NC_010511.1	3661528-3661571	1	0.977
NC_010511_29	29.1\|4808291\|44\|NC_010511\|CRISPRCasFinder	4808291-4808334	44	NC_010511.1	4477561-4477604	1	0.977
NC_010511_36	36.1\|6830766\|29\|NC_010511\|CRISPRCasFinder	6830766-6830794	29	NC_010511.1	3148171-3148199	1	0.966
NC_010511_36	36.1\|6830766\|29\|NC_010511\|CRISPRCasFinder	6830766-6830794	29	NC_010511.1	4808389-4808417	1	0.966
NC_010511_36	36.1\|6830766\|29\|NC_010511\|CRISPRCasFinder	6830766-6830794	29	NC_010511.1	5892075-5892103	1	0.966
NC_010511_1	1.1\|288577\|26\|NC_010511\|CRISPRCasFinder	288577-288602	26	NC_010511.1	2582361-2582386	2	0.923
NC_010511_1	1.1\|288577\|26\|NC_010511\|CRISPRCasFinder	288577-288602	26	NC_010511.1	56636-56661	2	0.923
NC_010511_1	1.1\|288577\|26\|NC_010511\|CRISPRCasFinder	288577-288602	26	NC_010511.1	56704-56729	2	0.923
NC_010511_2	2.1\|352331\|35\|NC_010511\|CRISPRCasFinder	352331-352365	35	NC_010511.1	3379149-3379183	2	0.943
NC_010511_8	8.1\|1156804\|58\|NC_010511\|CRISPRCasFinder	1156804-1156861	58	NC_010511.1	56728-56785	2	0.966
NC_010511_17	17.1\|3091259\|31\|NC_010511\|CRISPRCasFinder	3091259-3091289	31	NC_010511.1	56636-56666	2	0.935
NC_010511_17	17.1\|3091259\|31\|NC_010511\|CRISPRCasFinder	3091259-3091289	31	NC_010511.1	56704-56734	2	0.935
NC_010511_17	17.1\|3091259\|31\|NC_010511\|CRISPRCasFinder	3091259-3091289	31	NC_010511.1	5125122-5125152	2	0.935
NC_010511_19	19.1\|3439741\|45\|NC_010511\|CRISPRCasFinder	3439741-3439785	45	NC_010511.1	1978178-1978222	2	0.956
NC_010511_20	20.1\|3661604\|29\|NC_010511\|CRISPRCasFinder	3661604-3661632	29	NC_010511.1	2953403-2953431	2	0.931
NC_010511_20	20.1\|3661604\|29\|NC_010511\|CRISPRCasFinder	3661604-3661632	29	NC_010511.1	3252569-3252597	2	0.931
NC_010511_20	20.1\|3661604\|29\|NC_010511\|CRISPRCasFinder	3661604-3661632	29	NC_010511.1	3986276-3986304	2	0.931
NC_010511_20	20.1\|3661604\|29\|NC_010511\|CRISPRCasFinder	3661604-3661632	29	NC_010511.1	2075314-2075342	2	0.931
NC_010511_22	22.1\|3951416\|26\|NC_010511\|CRISPRCasFinder	3951416-3951441	26	NC_010511.1	1031948-1031973	2	0.923
NC_010511_22	22.1\|3951416\|26\|NC_010511\|CRISPRCasFinder	3951416-3951441	26	NC_010511.1	1883768-1883793	2	0.923
NC_010511_22	22.1\|3951416\|26\|NC_010511\|CRISPRCasFinder	3951416-3951441	26	NC_010511.1	2279730-2279755	2	0.923
NC_010511_22	22.1\|3951416\|26\|NC_010511\|CRISPRCasFinder	3951416-3951441	26	NC_010511.1	2360250-2360275	2	0.923
NC_010511_22	22.1\|3951416\|26\|NC_010511\|CRISPRCasFinder	3951416-3951441	26	NC_010511.1	3501858-3501883	2	0.923
NC_010511_22	22.1\|3951416\|26\|NC_010511\|CRISPRCasFinder	3951416-3951441	26	NC_010511.1	4201670-4201695	2	0.923
NC_010511_22	22.1\|3951416\|26\|NC_010511\|CRISPRCasFinder	3951416-3951441	26	NC_010511.1	4397334-4397359	2	0.923
NC_010511_22	22.1\|3951416\|26\|NC_010511\|CRISPRCasFinder	3951416-3951441	26	NC_010511.1	4786603-4786628	2	0.923
NC_010511_22	22.1\|3951416\|26\|NC_010511\|CRISPRCasFinder	3951416-3951441	26	NC_010511.1	6468477-6468502	2	0.923
NC_010511_22	22.1\|3951416\|26\|NC_010511\|CRISPRCasFinder	3951416-3951441	26	NC_010511.1	6992736-6992761	2	0.923
NC_010511_22	22.1\|3951416\|26\|NC_010511\|CRISPRCasFinder	3951416-3951441	26	NC_010511.1	7622403-7622428	2	0.923
NC_010511_23	23.1\|3970298\|41\|NC_010511\|CRISPRCasFinder	3970298-3970338	41	NC_010511.1	4778559-4778599	2	0.951
NC_010511_25	25.1\|4213563\|42\|NC_010511\|CRISPRCasFinder	4213563-4213604	42	NC_010511.1	1978181-1978222	2	0.952
NC_010511_25	25.1\|4213563\|42\|NC_010511\|CRISPRCasFinder	4213563-4213604	42	NC_010511.1	2953395-2953436	2	0.952
NC_010511_25	25.1\|4213563\|42\|NC_010511\|CRISPRCasFinder	4213563-4213604	42	NC_010511.1	5807372-5807413	2	0.952
NC_010511_25	25.1\|4213563\|42\|NC_010511\|CRISPRCasFinder	4213563-4213604	42	NC_010511.1	3070248-3070289	2	0.952
NC_010511_25	25.1\|4213563\|42\|NC_010511\|CRISPRCasFinder	4213563-4213604	42	NC_010511.1	6897312-6897353	2	0.952
NC_010511_29	29.1\|4808291\|44\|NC_010511\|CRISPRCasFinder	4808291-4808334	44	NC_010511.1	6410249-6410292	2	0.955
NC_010511_31	31.1\|4920641\|45\|NC_010511\|CRISPRCasFinder	4920641-4920685	45	NC_010511.1	5619222-5619266	2	0.956
NC_010511_36	36.1\|6830766\|29\|NC_010511\|CRISPRCasFinder	6830766-6830794	29	NC_010511.1	27822-27850	2	0.931
NC_010511_36	36.1\|6830766\|29\|NC_010511\|CRISPRCasFinder	6830766-6830794	29	NC_010511.1	973126-973154	2	0.931
NC_010511_36	36.1\|6830766\|29\|NC_010511\|CRISPRCasFinder	6830766-6830794	29	NC_010511.1	3832500-3832528	2	0.931

1. spacer 1.1|288577|26|NC_010511|CRISPRCasFinder matches to position: 5125122-5125147, mismatch: 0, identity: 1.0

tgcggagcaatccgtcggatgtcgta	CRISPR spacer
tgcggagcaatccgtcggatgtcgta	Protospacer
**************************

2. spacer 17.1|3091259|31|NC_010511|CRISPRCasFinder matches to position: 5207191-5207221, mismatch: 0, identity: 1.0

tgcgaagcaatccgtcggatgtcgtatccca	CRISPR spacer
tgcgaagcaatccgtcggatgtcgtatccca	Protospacer
*******************************

3. spacer 19.1|3439741|45|NC_010511|CRISPRCasFinder matches to position: 4201622-4201666, mismatch: 0, identity: 1.0

gcatacccaatccgctcgatcccttcgggatggcggattggggct	CRISPR spacer
gcatacccaatccgctcgatcccttcgggatggcggattggggct	Protospacer
*********************************************

4. spacer 19.1|3439741|45|NC_010511|CRISPRCasFinder matches to position: 6308360-6308404, mismatch: 0, identity: 1.0

gcatacccaatccgctcgatcccttcgggatggcggattggggct	CRISPR spacer
gcatacccaatccgctcgatcccttcgggatggcggattggggct	Protospacer
*********************************************

5. spacer 22.1|3951416|26|NC_010511|CRISPRCasFinder matches to position: 4106327-4106352, mismatch: 0, identity: 1.0

tctgacaagcccgcgcggcgcgtgag	CRISPR spacer
tctgacaagcccgcgcggcgcgtgag	Protospacer
**************************

6. spacer 24.1|4168034|33|NC_010511|CRISPRCasFinder matches to position: 5125007-5125039, mismatch: 0, identity: 1.0

acgtatgacaagcccgcgcggcgcctgagcgaa	CRISPR spacer
acgtatgacaagcccgcgcggcgcctgagcgaa	Protospacer
*********************************

7. spacer 25.1|4213563|42|NC_010511|CRISPRCasFinder matches to position: 4201625-4201666, mismatch: 0, identity: 1.0

tacccaatccgctcgatcccttcgggatggcggattggggct	CRISPR spacer
tacccaatccgctcgatcccttcgggatggcggattggggct	Protospacer
******************************************

8. spacer 25.1|4213563|42|NC_010511|CRISPRCasFinder matches to position: 6308360-6308401, mismatch: 0, identity: 1.0

tacccaatccgctcgatcccttcgggatggcggattggggct	CRISPR spacer
tacccaatccgctcgatcccttcgggatggcggattggggct	Protospacer
******************************************

9. spacer 29.1|4808291|44|NC_010511|CRISPRCasFinder matches to position: 3156598-3156641, mismatch: 0, identity: 1.0

caaatccgccatcccgaagggatcaagcggatttggtatgacac	CRISPR spacer
caaatccgccatcccgaagggatcaagcggatttggtatgacac	Protospacer
********************************************

10. spacer 1.1|288577|26|NC_010511|CRISPRCasFinder matches to position: 5207196-5207221, mismatch: 1, identity: 0.962

tgcggagcaatccgtcggatgtcgta	CRISPR spacer
tgcgaagcaatccgtcggatgtcgta	Protospacer
****.*********************

11. spacer 1.1|288577|26|NC_010511|CRISPRCasFinder matches to position: 4106371-4106396, mismatch: 1, identity: 0.962

tgcggagcaatccgtcggatgtcgta	CRISPR spacer
tgcgaagcaatccgtcggatgtcgta	Protospacer
****.*********************

12. spacer 1.1|288577|26|NC_010511|CRISPRCasFinder matches to position: 5125054-5125079, mismatch: 1, identity: 0.962

tgcggagcaatccgtcggatgtcgta	CRISPR spacer
tgcgaagcaatccgtcggatgtcgta	Protospacer
****.*********************

13. spacer 17.1|3091259|31|NC_010511|CRISPRCasFinder matches to position: 5125054-5125084, mismatch: 1, identity: 0.968

tgcgaagcaatccgtcggatgtcgtatccca	CRISPR spacer
tgcgaagcaatccgtcggatgtcgtatgcca	Protospacer
*************************** ***

14. spacer 19.1|3439741|45|NC_010511|CRISPRCasFinder matches to position: 6308429-6308473, mismatch: 1, identity: 0.978

gcatacccaatccgctcgatcccttcgggatggcggattggggct	CRISPR spacer
gcatacccaatccgctcgatctcttcgggatggcggattggggct	Protospacer
*********************.***********************

15. spacer 20.1|3661604|29|NC_010511|CRISPRCasFinder matches to position: 6742392-6742420, mismatch: 1, identity: 0.966

ccgcttgatcccttcgggatggcggattc	CRISPR spacer
ccgcgtgatcccttcgggatggcggattc	Protospacer
**** ************************

16. spacer 22.1|3951416|26|NC_010511|CRISPRCasFinder matches to position: 69415-69440, mismatch: 1, identity: 0.962

tctgacaagcccgcgcggcgcgtgag	CRISPR spacer
tctgacacgcccgcgcggcgcgtgag	Protospacer
******* ******************

17. spacer 22.1|3951416|26|NC_010511|CRISPRCasFinder matches to position: 567995-568020, mismatch: 1, identity: 0.962

tctgacaagcccgcgcggcgcgtgag	CRISPR spacer
tctgagaagcccgcgcggcgcgtgag	Protospacer
***** ********************

18. spacer 22.1|3951416|26|NC_010511|CRISPRCasFinder matches to position: 1140882-1140907, mismatch: 1, identity: 0.962

tctgacaagcccgcgcggcgcgtgag	CRISPR spacer
tctgccaagcccgcgcggcgcgtgag	Protospacer
**** *********************

19. spacer 22.1|3951416|26|NC_010511|CRISPRCasFinder matches to position: 2582405-2582430, mismatch: 1, identity: 0.962

tctgacaagcccgcgcggcgcgtgag	CRISPR spacer
tccgacaagcccgcgcggcgcgtgag	Protospacer
**.***********************

20. spacer 22.1|3951416|26|NC_010511|CRISPRCasFinder matches to position: 3820664-3820689, mismatch: 1, identity: 0.962

tctgacaagcccgcgcggcgcgtgag	CRISPR spacer
tctgacaagcccgcgcggcgcttgag	Protospacer
********************* ****

21. spacer 22.1|3951416|26|NC_010511|CRISPRCasFinder matches to position: 4213608-4213633, mismatch: 1, identity: 0.962

tctgacaagcccgcgcggcgcgtgag	CRISPR spacer
tctgccaagcccgcgcggcgcgtgag	Protospacer
**** *********************

22. spacer 22.1|3951416|26|NC_010511|CRISPRCasFinder matches to position: 5099469-5099494, mismatch: 1, identity: 0.962

tctgacaagcccgcgcggcgcgtgag	CRISPR spacer
tctgccaagcccgcgcggcgcgtgag	Protospacer
**** *********************

23. spacer 22.1|3951416|26|NC_010511|CRISPRCasFinder matches to position: 7489610-7489635, mismatch: 1, identity: 0.962

tctgacaagcccgcgcggcgcgtgag	CRISPR spacer
tctgacgagcccgcgcggcgcgtgag	Protospacer
******.*******************

24. spacer 23.1|3970298|41|NC_010511|CRISPRCasFinder matches to position: 2067885-2067925, mismatch: 1, identity: 0.976

cccaaacccgcttgatcccttcgggatggcggattggggct	CRISPR spacer
cccaaatccgcttgatcccttcgggatggcggattggggct	Protospacer
******.**********************************

25. spacer 24.1|4168034|33|NC_010511|CRISPRCasFinder matches to position: 4094251-4094283, mismatch: 1, identity: 0.97

acgtatgacaagcccgcgcggcgcctgagcgaa	CRISPR spacer
acgtatcacaagcccgcgcggcgcctgagcgaa	Protospacer
****** **************************

26. spacer 25.1|4213563|42|NC_010511|CRISPRCasFinder matches to position: 217512-217553, mismatch: 1, identity: 0.976

tacccaatccgctcgatcccttcgggatggcggattggggct	CRISPR spacer
tacccaatccgcttgatcccttcgggatggcggattggggct	Protospacer
*************.****************************

27. spacer 25.1|4213563|42|NC_010511|CRISPRCasFinder matches to position: 3902323-3902364, mismatch: 1, identity: 0.976

tacccaatccgctcgatcccttcgggatggcggattggggct	CRISPR spacer
tacccaatccgcttgatcccttcgggatggcggattggggct	Protospacer
*************.****************************

28. spacer 25.1|4213563|42|NC_010511|CRISPRCasFinder matches to position: 4240522-4240563, mismatch: 1, identity: 0.976

tacccaatccgctcgatcccttcgggatggcggattggggct	CRISPR spacer
tacccaatccgcttgatcccttcgggatggcggattggggct	Protospacer
*************.****************************

29. spacer 25.1|4213563|42|NC_010511|CRISPRCasFinder matches to position: 6308429-6308470, mismatch: 1, identity: 0.976

tacccaatccgctcgatcccttcgggatggcggattggggct	CRISPR spacer
tacccaatccgctcgatctcttcgggatggcggattggggct	Protospacer
******************.***********************

30. spacer 25.1|4213563|42|NC_010511|CRISPRCasFinder matches to position: 6763089-6763130, mismatch: 1, identity: 0.976

tacccaatccgctcgatcccttcgggatggcggattggggct	CRISPR spacer
taccaaatccgctcgatcccttcgggatggcggattggggct	Protospacer
**** *************************************

31. spacer 26.1|4322290|25|NC_010511|CRISPRCasFinder matches to position: 6184467-6184491, mismatch: 1, identity: 0.96

ttcccggtaccggaagtggtggtac	CRISPR spacer
tttccggtaccggaagtggtggtac	Protospacer
**.**********************

32. spacer 27.1|4397367|43|NC_010511|CRISPRCasFinder matches to position: 3902318-3902360, mismatch: 1, identity: 0.977

ccaatccgccatcccgaagggatcaagcggatttggtatgacg	CRISPR spacer
ccaatccgccatcccgaagggatcaagcggattgggtatgacg	Protospacer
********************************* *********

33. spacer 27.1|4397367|43|NC_010511|CRISPRCasFinder matches to position: 6763093-6763135, mismatch: 1, identity: 0.977

ccaatccgccatcccgaagggatcaagcggatttggtatgacg	CRISPR spacer
ccaatccgccatcccgaagggatcgagcggatttggtatgacg	Protospacer
************************.******************

34. spacer 29.1|4808291|44|NC_010511|CRISPRCasFinder matches to position: 1811107-1811150, mismatch: 1, identity: 0.977

caaatccgccatcccgaagggatcaagcggatttggtatgacac	CRISPR spacer
caaatccgccatcccgaagggatcaagcggatttggcatgacac	Protospacer
************************************.*******

35. spacer 29.1|4808291|44|NC_010511|CRISPRCasFinder matches to position: 3283937-3283980, mismatch: 1, identity: 0.977

caaatccgccatcccgaagggatcaagcggatttggtatgacac	CRISPR spacer
caaatccgccctcccgaagggatcaagcggatttggtatgacac	Protospacer
********** *********************************

36. spacer 29.1|4808291|44|NC_010511|CRISPRCasFinder matches to position: 3661528-3661571, mismatch: 1, identity: 0.977

caaatccgccatcccgaagggatcaagcggatttggtatgacac	CRISPR spacer
caaatccgccatcccgaagagatcaagcggatttggtatgacac	Protospacer
*******************.************************

37. spacer 29.1|4808291|44|NC_010511|CRISPRCasFinder matches to position: 4477561-4477604, mismatch: 1, identity: 0.977

caaatccgccatcccgaagggatcaagcggatttggtatgacac	CRISPR spacer
caaaaccgccatcccgaagggatcaagcggatttggtatgacac	Protospacer
**** ***************************************

38. spacer 36.1|6830766|29|NC_010511|CRISPRCasFinder matches to position: 3148171-3148199, mismatch: 1, identity: 0.966

gaagccatcaaccggatgtcggatgacac	CRISPR spacer
gaagccatcaaccggatgtcgtatgacac	Protospacer
********************* *******

39. spacer 36.1|6830766|29|NC_010511|CRISPRCasFinder matches to position: 4808389-4808417, mismatch: 1, identity: 0.966

gaagccatcaaccggatgtcggatgacac	CRISPR spacer
gaagccatcaaccggatggcggatgacac	Protospacer
****************** **********

40. spacer 36.1|6830766|29|NC_010511|CRISPRCasFinder matches to position: 5892075-5892103, mismatch: 1, identity: 0.966

gaagccatcaaccggatgtcggatgacac	CRISPR spacer
gaagccatcaaccggatgtcggatgaaac	Protospacer
************************** **

41. spacer 1.1|288577|26|NC_010511|CRISPRCasFinder matches to position: 2582361-2582386, mismatch: 2, identity: 0.923

tgcggagcaatccgtcggatgtcgta	CRISPR spacer
tgcgaagcaatccgtcggatttcgta	Protospacer
****.*************** *****

42. spacer 1.1|288577|26|NC_010511|CRISPRCasFinder matches to position: 56636-56661, mismatch: 2, identity: 0.923

tgcggagcaatccgtcggatgtcgta	CRISPR spacer
tgcgaagcaattcgtcggatgtcgta	Protospacer
****.******.**************

43. spacer 1.1|288577|26|NC_010511|CRISPRCasFinder matches to position: 56704-56729, mismatch: 2, identity: 0.923

tgcggagcaatccgtcggatgtcgta	CRISPR spacer
tgcgaagcaattcgtcggatgtcgta	Protospacer
****.******.**************

44. spacer 2.1|352331|35|NC_010511|CRISPRCasFinder matches to position: 3379149-3379183, mismatch: 2, identity: 0.943

tcatgatccgctcgatcccttcgggatggcggatc	CRISPR spacer
tcgtgatccgctcgatcccttcgggatgtcggatc	Protospacer
**.************************* ******

45. spacer 8.1|1156804|58|NC_010511|CRISPRCasFinder matches to position: 56728-56785, mismatch: 2, identity: 0.966

tatgacaagcccgcgcggcgcttgagcgaagccgacatccgcatggccgaaaggggag	CRISPR spacer
tatgccaagcccgcgcggcgcttgagcgaagccgacatccgcatggccgaaatgggag	Protospacer
**** *********************************************** *****

46. spacer 17.1|3091259|31|NC_010511|CRISPRCasFinder matches to position: 56636-56666, mismatch: 2, identity: 0.935

tgcgaagcaatccgtcggatgtcgtatccca	CRISPR spacer
tgcgaagcaattcgtcggatgtcgtatgcca	Protospacer
***********.*************** ***

47. spacer 17.1|3091259|31|NC_010511|CRISPRCasFinder matches to position: 56704-56734, mismatch: 2, identity: 0.935

tgcgaagcaatccgtcggatgtcgtatccca	CRISPR spacer
tgcgaagcaattcgtcggatgtcgtatgcca	Protospacer
***********.*************** ***

48. spacer 17.1|3091259|31|NC_010511|CRISPRCasFinder matches to position: 5125122-5125152, mismatch: 2, identity: 0.935

tgcgaagcaatccgtcggatgtcgtatccca	CRISPR spacer
tgcggagcaatccgtcggatgtcgtatgcca	Protospacer
****.********************** ***

49. spacer 19.1|3439741|45|NC_010511|CRISPRCasFinder matches to position: 1978178-1978222, mismatch: 2, identity: 0.956

gcatacccaatccgctcgatcccttcgggatggcggattggggct	CRISPR spacer
gcatacccaatccgcttgatcccttcgggatggcggatcggggct	Protospacer
****************.*********************.******

50. spacer 20.1|3661604|29|NC_010511|CRISPRCasFinder matches to position: 2953403-2953431, mismatch: 2, identity: 0.931

ccgcttgatcccttcgggatggcggattc	CRISPR spacer
ccgctcgatcccttcgggatggcgggttc	Protospacer
*****.*******************.***

51. spacer 20.1|3661604|29|NC_010511|CRISPRCasFinder matches to position: 3252569-3252597, mismatch: 2, identity: 0.931

ccgcttgatcccttcgggatggcggattc	CRISPR spacer
ccgctcgatcccttcgggatgtcggattc	Protospacer
*****.*************** *******

52. spacer 20.1|3661604|29|NC_010511|CRISPRCasFinder matches to position: 3986276-3986304, mismatch: 2, identity: 0.931

ccgcttgatcccttcgggatggcggattc	CRISPR spacer
ccgcttgatcccttcgggacggcggcttc	Protospacer
*******************.***** ***

53. spacer 20.1|3661604|29|NC_010511|CRISPRCasFinder matches to position: 2075314-2075342, mismatch: 2, identity: 0.931

ccgcttgatcccttcgggatggcggattc	CRISPR spacer
ccgatcgatcccttcgggatggcggattc	Protospacer
*** *.***********************

54. spacer 22.1|3951416|26|NC_010511|CRISPRCasFinder matches to position: 1031948-1031973, mismatch: 2, identity: 0.923

tctgacaagcccgcgcggcgcgtgag	CRISPR spacer
tctgccaagcccgcgcggcgcttgag	Protospacer
**** **************** ****

55. spacer 22.1|3951416|26|NC_010511|CRISPRCasFinder matches to position: 1883768-1883793, mismatch: 2, identity: 0.923

tctgacaagcccgcgcggcgcgtgag	CRISPR spacer
tctgacacgcccgcgcggcgcctgag	Protospacer
******* ************* ****

56. spacer 22.1|3951416|26|NC_010511|CRISPRCasFinder matches to position: 2279730-2279755, mismatch: 2, identity: 0.923

tctgacaagcccgcgcggcgcgtgag	CRISPR spacer
tctgccaagcccgcgcggcgcctgag	Protospacer
**** **************** ****

57. spacer 22.1|3951416|26|NC_010511|CRISPRCasFinder matches to position: 2360250-2360275, mismatch: 2, identity: 0.923

tctgacaagcccgcgcggcgcgtgag	CRISPR spacer
tctgagaagcccgcgcggcgcttgag	Protospacer
***** *************** ****

58. spacer 22.1|3951416|26|NC_010511|CRISPRCasFinder matches to position: 3501858-3501883, mismatch: 2, identity: 0.923

tctgacaagcccgcgcggcgcgtgag	CRISPR spacer
tctgccaagcccgcgcggcgcttgag	Protospacer
**** **************** ****

59. spacer 22.1|3951416|26|NC_010511|CRISPRCasFinder matches to position: 4201670-4201695, mismatch: 2, identity: 0.923

tctgacaagcccgcgcggcgcgtgag	CRISPR spacer
tctgccaagcccgcgcggcgcctgag	Protospacer
**** **************** ****

60. spacer 22.1|3951416|26|NC_010511|CRISPRCasFinder matches to position: 4397334-4397359, mismatch: 2, identity: 0.923

tctgacaagcccgcgcggcgcgtgag	CRISPR spacer
tctgccaagcccgcgcggcgcttgag	Protospacer
**** **************** ****

61. spacer 22.1|3951416|26|NC_010511|CRISPRCasFinder matches to position: 4786603-4786628, mismatch: 2, identity: 0.923

tctgacaagcccgcgcggcgcgtgag	CRISPR spacer
tctgccaagcccgcgcggcgcctgag	Protospacer
**** **************** ****

62. spacer 22.1|3951416|26|NC_010511|CRISPRCasFinder matches to position: 6468477-6468502, mismatch: 2, identity: 0.923

tctgacaagcccgcgcggcgcgtgag	CRISPR spacer
tctgacacgcccgggcggcgcgtgag	Protospacer
******* ***** ************

63. spacer 22.1|3951416|26|NC_010511|CRISPRCasFinder matches to position: 6992736-6992761, mismatch: 2, identity: 0.923

tctgacaagcccgcgcggcgcgtgag	CRISPR spacer
tctgacgagcccgcgcggcgcttgag	Protospacer
******.************** ****

64. spacer 22.1|3951416|26|NC_010511|CRISPRCasFinder matches to position: 7622403-7622428, mismatch: 2, identity: 0.923

tctgacaagcccgcgcggcgcgtgag	CRISPR spacer
tctgccaagcccgcgcggcgcttgag	Protospacer
**** **************** ****

65. spacer 23.1|3970298|41|NC_010511|CRISPRCasFinder matches to position: 4778559-4778599, mismatch: 2, identity: 0.951

cccaaacccgcttgatcccttcgggatggcggattggggct	CRISPR spacer
cccaaatccgcttgatcccttcgggatggcggatttgggct	Protospacer
******.**************************** *****

66. spacer 25.1|4213563|42|NC_010511|CRISPRCasFinder matches to position: 1978181-1978222, mismatch: 2, identity: 0.952

tacccaatccgctcgatcccttcgggatggcggattggggct	CRISPR spacer
tacccaatccgcttgatcccttcgggatggcggatcggggct	Protospacer
*************.*********************.******

67. spacer 25.1|4213563|42|NC_010511|CRISPRCasFinder matches to position: 2953395-2953436, mismatch: 2, identity: 0.952

tacccaatccgctcgatcccttcgggatggcggattggggct	CRISPR spacer
tacccaatccgctcgatcccttcgggatggcgggttcgggct	Protospacer
*********************************.** *****

68. spacer 25.1|4213563|42|NC_010511|CRISPRCasFinder matches to position: 5807372-5807413, mismatch: 2, identity: 0.952

tacccaatccgctcgatcccttcgggatggcggattggggct	CRISPR spacer
tacccaatccgcttgatcccttcgggatggcggattgcggct	Protospacer
*************.*********************** ****

69. spacer 25.1|4213563|42|NC_010511|CRISPRCasFinder matches to position: 3070248-3070289, mismatch: 2, identity: 0.952

tacccaatccgctcgatcccttcgggatggcggattggggct	CRISPR spacer
tacccaatccgctcgatccctccgggatggcggatttgggct	Protospacer
*********************.************** *****

70. spacer 25.1|4213563|42|NC_010511|CRISPRCasFinder matches to position: 6897312-6897353, mismatch: 2, identity: 0.952

tacccaatccgctcgatcccttcgggatggcggattggggct	CRISPR spacer
tacccaatccgcatgatcccttcgggatggcggattggggct	Protospacer
************ .****************************

71. spacer 29.1|4808291|44|NC_010511|CRISPRCasFinder matches to position: 6410249-6410292, mismatch: 2, identity: 0.955

caaatccgccatcccgaagggatcaagcggatttggtatgacac	CRISPR spacer
caaagccgccatcccgaagggatcaagcggatttgggatgacac	Protospacer
**** ******************************* *******

72. spacer 31.1|4920641|45|NC_010511|CRISPRCasFinder matches to position: 5619222-5619266, mismatch: 2, identity: 0.956

gatgtggatgtcggcttcgctcaggcgccgcgcgggcttggcata	CRISPR spacer
gatgcggatgtcggcttcgctcaagcgccgcgcgggcttggcata	Protospacer
****.******************.*********************

73. spacer 36.1|6830766|29|NC_010511|CRISPRCasFinder matches to position: 27822-27850, mismatch: 2, identity: 0.931

gaagccatcaaccggatgtcggatgacac	CRISPR spacer
gaagccatcaaccggaggtcggatgagac	Protospacer
**************** ********* **

74. spacer 36.1|6830766|29|NC_010511|CRISPRCasFinder matches to position: 973126-973154, mismatch: 2, identity: 0.931

gaagccatcaaccggatgtcggatgacac	CRISPR spacer
gaagccatcgaccggatgtcggatgagac	Protospacer
*********.**************** **

75. spacer 36.1|6830766|29|NC_010511|CRISPRCasFinder matches to position: 3832500-3832528, mismatch: 2, identity: 0.931

gaagccatcaaccggatgtcggatgacac	CRISPR spacer
gaagccatcaaccggatggcggatgagac	Protospacer
****************** ******* **

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NC_010511_26	26.1\|4322290\|25\|NC_010511\|CRISPRCasFinder	4322290-4322314	25	NZ_CP023068	Ensifer sojae CCBAU 05684 plasmid pSJ05684b, complete sequence	1951477-1951501	4	0.84
NC_010511_22	22.1\|3951416\|26\|NC_010511\|CRISPRCasFinder	3951416-3951441	26	NZ_CP042265	Litoreibacter sp. LN3S51 plasmid unnamed4, complete sequence	202022-202047	5	0.808
NC_010511_22	22.1\|3951416\|26\|NC_010511\|CRISPRCasFinder	3951416-3951441	26	NZ_CP016462	Blastomonas sp. RAC04 plasmid pBSY18_1, complete sequence	32481-32506	5	0.808
NC_010511_22	22.1\|3951416\|26\|NC_010511\|CRISPRCasFinder	3951416-3951441	26	NZ_AP022319	Burkholderia sp. THE68 plasmid BTHE68_p1, complete sequence	1191340-1191365	5	0.808
NC_010511_26	26.1\|4322290\|25\|NC_010511\|CRISPRCasFinder	4322290-4322314	25	NZ_CP018654	Salmonella enterica subsp. enterica serovar Enteritidis strain 81-1705 plasmid pSE81-1705-3, complete sequence	11830-11854	5	0.8
NC_010511_34	34.16\|6320910\|35\|NC_010511\|CRISPRCasFinder	6320910-6320944	35	KR063279	Gordonia phage GMA3, complete genome	66896-66930	6	0.829
NC_010511_36	36.1\|6830766\|29\|NC_010511\|CRISPRCasFinder	6830766-6830794	29	NZ_CP044217	Mesorhizobium sp. NIBRBAC000500504 plasmid unnamed, complete sequence	290100-290128	6	0.793
NC_010511_6	6.1\|725596\|32\|NC_010511\|CRISPRCasFinder	725596-725627	32	NC_017793	Deinococcus gobiensis I-0 plasmid P6, complete sequence	50330-50361	7	0.781
NC_010511_6	6.1\|725596\|32\|NC_010511\|CRISPRCasFinder	725596-725627	32	NZ_CP049244	Rhizobium pseudoryzae strain DSM 19479 plasmid unnamed3, complete sequence	259584-259615	7	0.781
NC_010511_6	6.1\|725596\|32\|NC_010511\|CRISPRCasFinder	725596-725627	32	NZ_CP015740	Shinella sp. HZN7 plasmid pShin-04, complete sequence	93158-93189	7	0.781
NC_010511_6	6.1\|725596\|32\|NC_010511\|CRISPRCasFinder	725596-725627	32	NZ_LR594664	Variovorax sp. RA8 plasmid 3	286428-286459	7	0.781
NC_010511_11	11.4\|1944015\|35\|NC_010511\|PILER-CR,CRISPRCasFinder,CRT	1944015-1944049	35	NC_022043	Paracoccus aminophilus JCM 7686 plasmid pAMI5, complete sequence	21096-21130	7	0.8
NC_010511_11	11.5\|1944081\|34\|NC_010511\|PILER-CR,CRISPRCasFinder,CRT	1944081-1944114	34	NZ_CP003988	Streptomyces sp. 769 plasmid pSGZL, complete sequence	117568-117601	7	0.794
NC_010511_34	34.4\|6320098\|34\|NC_010511\|CRISPRCasFinder	6320098-6320131	34	NZ_CP016613	Ralstonia solanacearum FJAT-91 plasmid unnamed1, complete sequence	405353-405386	7	0.794
NC_010511_34	34.4\|6320098\|34\|NC_010511\|CRISPRCasFinder	6320098-6320131	34	NZ_CP021449	Ralstonia solanacearum strain SEPPX05 plasmid pSEPPX05, complete sequence	1851596-1851629	7	0.794
NC_010511_34	34.4\|6320098\|34\|NC_010511\|CRISPRCasFinder	6320098-6320131	34	CP023013	Ralstonia solanacearum strain T110 plasmid unnamed, complete sequence	221097-221130	7	0.794
NC_010511_34	34.4\|6320098\|34\|NC_010511\|CRISPRCasFinder	6320098-6320131	34	NZ_CP049790	Ralstonia solanacearum strain 202 plasmid unnamed, complete sequence	240943-240976	7	0.794
NC_010511_34	34.4\|6320098\|34\|NC_010511\|CRISPRCasFinder	6320098-6320131	34	NZ_CP049794	Ralstonia solanacearum strain 204 plasmid unnamed, complete sequence	410703-410736	7	0.794
NC_010511_34	34.4\|6320098\|34\|NC_010511\|CRISPRCasFinder	6320098-6320131	34	NZ_CP049788	Ralstonia solanacearum strain B2 plasmid unnamed, complete sequence	1716909-1716942	7	0.794
NC_010511_34	34.4\|6320098\|34\|NC_010511\|CRISPRCasFinder	6320098-6320131	34	NZ_CP022766	Ralstonia solanacearum strain T78 plasmid unnamed, complete sequence	223728-223761	7	0.794
NC_010511_34	34.4\|6320098\|34\|NC_010511\|CRISPRCasFinder	6320098-6320131	34	NZ_CP018784	Curtobacterium pusillum strain AA3 plasmid pCPAA3, complete sequence	319109-319142	7	0.794
NC_010511_34	34.4\|6320098\|34\|NC_010511\|CRISPRCasFinder	6320098-6320131	34	NZ_CP021763	Ralstonia pseudosolanacearum strain RS 476 plasmid unnamed, complete sequence	285110-285143	7	0.794
NC_010511_34	34.4\|6320098\|34\|NC_010511\|CRISPRCasFinder	6320098-6320131	34	NZ_CP015116	Ralstonia solanacearum strain EP1 plasmid unnamed, complete sequence	377164-377197	7	0.794
NC_010511_34	34.4\|6320098\|34\|NC_010511\|CRISPRCasFinder	6320098-6320131	34	NZ_CP016555	Ralstonia solanacearum FJAT-1458 plasmid plas1, complete sequence	1951564-1951597	7	0.794
NC_010511_34	34.4\|6320098\|34\|NC_010511\|CRISPRCasFinder	6320098-6320131	34	NZ_CP049792	Ralstonia solanacearum strain 203 plasmid unnamed, complete sequence	192179-192212	7	0.794
NC_010511_34	34.4\|6320098\|34\|NC_010511\|CRISPRCasFinder	6320098-6320131	34	NZ_CP052069	Ralstonia solanacearum strain FJAT91.F50 plasmid Plas1, complete sequence	224673-224706	7	0.794
NC_010511_34	34.4\|6320098\|34\|NC_010511\|CRISPRCasFinder	6320098-6320131	34	NZ_CP016915	Ralstonia solanacearum strain CQPS-1 plasmid unnamed, complete sequence	835757-835790	7	0.794
NC_010511_34	34.4\|6320098\|34\|NC_010511\|CRISPRCasFinder	6320098-6320131	34	NZ_CP016905	Ralstonia solanacearum strain KACC 10709 plasmid unnamed1	1213750-1213783	7	0.794
NC_010511_34	34.4\|6320098\|34\|NC_010511\|CRISPRCasFinder	6320098-6320131	34	NZ_CP025986	Ralstonia solanacearum strain RSCM plasmid p-unname2, complete sequence	88622-88655	7	0.794
NC_010511_34	34.4\|6320098\|34\|NC_010511\|CRISPRCasFinder	6320098-6320131	34	NZ_CP022769	Ralstonia solanacearum strain T60 plasmid unnamed, complete sequence	224987-225020	7	0.794
NC_010511_34	34.4\|6320098\|34\|NC_010511\|CRISPRCasFinder	6320098-6320131	34	NZ_CP015851	Ralstonia solanacearum strain YC40-M plasmid, complete sequence	166265-166298	7	0.794
NC_010511_34	34.4\|6320098\|34\|NC_010511\|CRISPRCasFinder	6320098-6320131	34	NZ_CP022773	Ralstonia solanacearum strain T42 plasmid unnamed, complete sequence	232022-232055	7	0.794
NC_010511_34	34.4\|6320098\|34\|NC_010511\|CRISPRCasFinder	6320098-6320131	34	NZ_CP022783	Ralstonia solanacearum strain SL3755 plasmid unnamed, complete sequence	222179-222212	7	0.794
NC_010511_34	34.4\|6320098\|34\|NC_010511\|CRISPRCasFinder	6320098-6320131	34	NZ_CP022791	Ralstonia solanacearum strain SL3103 plasmid unnamed, complete sequence	113505-113538	7	0.794
NC_010511_34	34.4\|6320098\|34\|NC_010511\|CRISPRCasFinder	6320098-6320131	34	NZ_CP022795	Ralstonia solanacearum strain SL2330 plasmid unnamed, complete sequence	221312-221345	7	0.794
NC_010511_34	34.4\|6320098\|34\|NC_010511\|CRISPRCasFinder	6320098-6320131	34	NZ_CP052071	Ralstonia solanacearum strain FJAT454.F1 plasmid Plas1, complete sequence	237796-237829	7	0.794
NC_010511_34	34.4\|6320098\|34\|NC_010511\|CRISPRCasFinder	6320098-6320131	34	NZ_CP022482	Ralstonia solanacearum strain HA4-1 plasmid HA4-1MP, complete sequence	867356-867389	7	0.794
NC_010511_34	34.4\|6320098\|34\|NC_010511\|CRISPRCasFinder	6320098-6320131	34	NZ_CP009763	Ralstonia solanacearum OE1-1 plasmid unnamed, complete sequence	218051-218084	7	0.794
NC_010511_34	34.4\|6320098\|34\|NC_010511\|CRISPRCasFinder	6320098-6320131	34	CP023015	Ralstonia solanacearum strain T25 plasmid unnamed, complete sequence	222437-222470	7	0.794
NC_010511_34	34.4\|6320098\|34\|NC_010511\|CRISPRCasFinder	6320098-6320131	34	NZ_CP022779	Ralstonia solanacearum strain SL3882 plasmid unnamed, complete sequence	225004-225037	7	0.794
NC_010511_34	34.4\|6320098\|34\|NC_010511\|CRISPRCasFinder	6320098-6320131	34	NZ_CP052075	Ralstonia solanacearum strain FJAT448.F1 plasmid Plas1, complete sequence	237796-237829	7	0.794
NC_010511_34	34.4\|6320098\|34\|NC_010511\|CRISPRCasFinder	6320098-6320131	34	NZ_CP052085	Ralstonia solanacearum strain FJAT15353.F8 plasmid Plas1, complete sequence	239408-239441	7	0.794
NC_010511_34	34.4\|6320098\|34\|NC_010511\|CRISPRCasFinder	6320098-6320131	34	NZ_CP052095	Ralstonia solanacearum strain FJAT15340.F1 plasmid Plas1, complete sequence	223697-223730	7	0.794
NC_010511_34	34.4\|6320098\|34\|NC_010511\|CRISPRCasFinder	6320098-6320131	34	NZ_CP052105	Ralstonia solanacearum strain FJAT15252.F1 plasmid Plas1, complete sequence	237796-237829	7	0.794
NC_010511_34	34.4\|6320098\|34\|NC_010511\|CRISPRCasFinder	6320098-6320131	34	NZ_CP052077	Ralstonia solanacearum strain FJAT445.F50 plasmid Plas1, complete sequence	217094-217127	7	0.794
NC_010511_34	34.4\|6320098\|34\|NC_010511\|CRISPRCasFinder	6320098-6320131	34	NZ_CP052087	Ralstonia solanacearum strain FJAT15353.F50 plasmid Plas1, complete sequence	239408-239441	7	0.794
NC_010511_34	34.4\|6320098\|34\|NC_010511\|CRISPRCasFinder	6320098-6320131	34	NZ_CP052097	Ralstonia solanacearum strain FJAT15304.F6 plasmid Plas1, complete sequence	223697-223730	7	0.794
NC_010511_34	34.4\|6320098\|34\|NC_010511\|CRISPRCasFinder	6320098-6320131	34	NZ_CP052115	Ralstonia solanacearum strain FJAT1463.F50 plasmid Plas1, complete sequence	237796-237829	7	0.794
NC_010511_34	34.4\|6320098\|34\|NC_010511\|CRISPRCasFinder	6320098-6320131	34	NZ_CP052127	Ralstonia solanacearum strain FJAT1303.F50 plasmid Plas1, complete sequence	239408-239441	7	0.794
NC_010511_34	34.4\|6320098\|34\|NC_010511\|CRISPRCasFinder	6320098-6320131	34	NZ_CP052079	Ralstonia solanacearum strain FJAT445.F1 plasmid Plas1, complete sequence	217094-217127	7	0.794
NC_010511_34	34.4\|6320098\|34\|NC_010511\|CRISPRCasFinder	6320098-6320131	34	NZ_CP052089	Ralstonia solanacearum strain FJAT15353.F1 plasmid Plas1, complete sequence	239408-239441	7	0.794
NC_010511_34	34.4\|6320098\|34\|NC_010511\|CRISPRCasFinder	6320098-6320131	34	NZ_CP052093	Ralstonia solanacearum strain FJAT15340.F50 plasmid Plas1, complete sequence	223697-223730	7	0.794
NC_010511_34	34.4\|6320098\|34\|NC_010511\|CRISPRCasFinder	6320098-6320131	34	NZ_CP052101	Ralstonia solanacearum strain FJAT15304.F1 plasmid Plas1, complete sequence	223697-223730	7	0.794
NC_010511_34	34.4\|6320098\|34\|NC_010511\|CRISPRCasFinder	6320098-6320131	34	NZ_CP052099	Ralstonia solanacearum strain FJAT15304.F50 plasmid Plas1, complete sequence	223697-223730	7	0.794
NC_010511_34	34.4\|6320098\|34\|NC_010511\|CRISPRCasFinder	6320098-6320131	34	NZ_CP052107	Ralstonia solanacearum strain FJAT15249.F50 plasmid Plas1, complete sequence	237796-237829	7	0.794
NC_010511_34	34.4\|6320098\|34\|NC_010511\|CRISPRCasFinder	6320098-6320131	34	NZ_CP022781	Ralstonia solanacearum strain SL3822 plasmid unnamed, complete sequence	1872875-1872908	7	0.794
NC_010511_34	34.4\|6320098\|34\|NC_010511\|CRISPRCasFinder	6320098-6320131	34	NZ_CP052117	Ralstonia solanacearum strain FJAT1463.F1 plasmid Plas1, complete sequence	237796-237829	7	0.794
NC_010511_34	34.4\|6320098\|34\|NC_010511\|CRISPRCasFinder	6320098-6320131	34	NZ_CP052125	Ralstonia solanacearum strain FJAT1452.F1 plasmid Plas1, complete sequence	217094-217127	7	0.794
NC_010511_34	34.4\|6320098\|34\|NC_010511\|CRISPRCasFinder	6320098-6320131	34	NZ_CP022793	Ralstonia solanacearum strain SL2729 plasmid unnamed, complete sequence	232005-232038	7	0.794
NC_010511_34	34.4\|6320098\|34\|NC_010511\|CRISPRCasFinder	6320098-6320131	34	NZ_CP022785	Ralstonia solanacearum strain SL3730 plasmid unnamed, complete sequence	232007-232040	7	0.794
NC_010511_34	34.4\|6320098\|34\|NC_010511\|CRISPRCasFinder	6320098-6320131	34	NZ_CP022787	Ralstonia solanacearum strain SL3300 plasmid unnamed, complete sequence	228607-228640	7	0.794
NC_010511_34	34.4\|6320098\|34\|NC_010511\|CRISPRCasFinder	6320098-6320131	34	NZ_CP022756	Ralstonia solanacearum strain T117 plasmid unnamed, complete sequence	226747-226780	7	0.794
NC_010511_34	34.4\|6320098\|34\|NC_010511\|CRISPRCasFinder	6320098-6320131	34	NZ_CP052129	Ralstonia solanacearum strain FJAT1303.F1 plasmid Plas1, complete sequence	222208-222241	7	0.794
NC_010511_34	34.4\|6320098\|34\|NC_010511\|CRISPRCasFinder	6320098-6320131	34	NZ_CP052121	Ralstonia solanacearum strain FJAT1458.F1 plasmid Plas1, complete sequence	237796-237829	7	0.794
NC_010511_34	34.4\|6320098\|34\|NC_010511\|CRISPRCasFinder	6320098-6320131	34	NZ_CP052123	Ralstonia solanacearum strain FJAT1452.F50 plasmid Plas1, complete sequence	217094-217127	7	0.794
NC_010511_34	34.4\|6320098\|34\|NC_010511\|CRISPRCasFinder	6320098-6320131	34	NZ_CP052131	Ralstonia solanacearum strain FJAT1303.F8 plasmid Plas1, complete sequence	239408-239441	7	0.794
NC_010511_34	34.4\|6320098\|34\|NC_010511\|CRISPRCasFinder	6320098-6320131	34	CP011998	Ralstonia solanacearum strain YC45 plasmid, complete sequence	267266-267299	7	0.794
NC_010511_34	34.4\|6320098\|34\|NC_010511\|CRISPRCasFinder	6320098-6320131	34	NZ_CP052073	Ralstonia solanacearum strain FJAT448.F50 plasmid Plas1, complete sequence	237796-237829	7	0.794
NC_010511_34	34.4\|6320098\|34\|NC_010511\|CRISPRCasFinder	6320098-6320131	34	NZ_CP052081	Ralstonia solanacearum strain FJAT442.F50 plasmid Plas1, complete sequence	217094-217127	7	0.794
NC_010511_34	34.4\|6320098\|34\|NC_010511\|CRISPRCasFinder	6320098-6320131	34	NZ_CP052083	Ralstonia solanacearum strain FJAT442.F1 plasmid Plas1, complete sequence	217094-217127	7	0.794
NC_010511_34	34.4\|6320098\|34\|NC_010511\|CRISPRCasFinder	6320098-6320131	34	NZ_CP052109	Ralstonia solanacearum strain FJAT15249.F1 plasmid Plas1, complete sequence	237796-237829	7	0.794
NC_010511_34	34.4\|6320098\|34\|NC_010511\|CRISPRCasFinder	6320098-6320131	34	NZ_CP052091	Ralstonia solanacearum strain FJAT15340.F6 plasmid Plas1, complete sequence	223697-223730	7	0.794
NC_010511_34	34.4\|6320098\|34\|NC_010511\|CRISPRCasFinder	6320098-6320131	34	NZ_CP052111	Ralstonia solanacearum strain FJAT15244.F50 plasmid Plas1, complete sequence	1854977-1855010	7	0.794
NC_010511_34	34.4\|6320098\|34\|NC_010511\|CRISPRCasFinder	6320098-6320131	34	NZ_CP052103	Ralstonia solanacearum strain FJAT15252.F50 plasmid Plas1, complete sequence	237796-237829	7	0.794
NC_010511_34	34.4\|6320098\|34\|NC_010511\|CRISPRCasFinder	6320098-6320131	34	NZ_CP052119	Ralstonia solanacearum strain FJAT1458.F50 plasmid Plas1, complete sequence	237796-237829	7	0.794
NC_010511_34	34.4\|6320098\|34\|NC_010511\|CRISPRCasFinder	6320098-6320131	34	NZ_CP052113	Ralstonia solanacearum strain FJAT15244.F1 plasmid Plas1, complete sequence	1854977-1855010	7	0.794
NC_010511_36	36.1\|6830766\|29\|NC_010511\|CRISPRCasFinder	6830766-6830794	29	NZ_CP032349	Azospirillum brasilense strain MTCC4039 plasmid p3, complete sequence	161801-161829	7	0.759
NC_010511_6	6.1\|725596\|32\|NC_010511\|CRISPRCasFinder	725596-725627	32	NZ_CP021821	Sinorhizobium meliloti strain M162 plasmid accessoryA, complete sequence	320968-320999	8	0.75
NC_010511_6	6.1\|725596\|32\|NC_010511\|CRISPRCasFinder	725596-725627	32	NZ_CP021813	Sinorhizobium meliloti strain M270 plasmid psymA, complete sequence	655892-655923	8	0.75
NC_010511_11	11.4\|1944015\|35\|NC_010511\|PILER-CR,CRISPRCasFinder,CRT	1944015-1944049	35	NZ_CP030828	Neorhizobium sp. NCHU2750 plasmid pNCHU2750a, complete sequence	609927-609961	8	0.771
NC_010511_14	14.3\|2625295\|33\|NC_010511\|PILER-CR,CRISPRCasFinder,CRT	2625295-2625327	33	NZ_CP022666	Rhizobium leguminosarum bv. viciae strain BIHB 1217 plasmid pPR1, complete sequence	1040794-1040826	8	0.758
NC_010511_14	14.3\|2625295\|33\|NC_010511\|PILER-CR,CRISPRCasFinder,CRT	2625295-2625327	33	NZ_CP050086	Rhizobium leguminosarum bv. trifolii strain 23B plasmid pRL23b7, complete sequence	637930-637962	8	0.758
NC_010511_17	17.1\|3091259\|31\|NC_010511\|CRISPRCasFinder	3091259-3091289	31	NZ_CP010408	Streptomyces vietnamensis strain GIMV4.0001 plasmid pSVL1, complete sequence	186236-186266	8	0.742
NC_010511_24	24.1\|4168034\|33\|NC_010511\|CRISPRCasFinder	4168034-4168066	33	NZ_CP032319	Hymenobacter oligotrophus strain sh-6 plasmid unnamed2, complete sequence	4583-4615	8	0.758
NC_010511_34	34.1\|6319896\|34\|NC_010511\|CRISPRCasFinder	6319896-6319929	34	NZ_CP016452	Sinorhizobium sp. RAC02 plasmid pBSY16_1, complete sequence	681463-681496	8	0.765
NC_010511_34	34.4\|6320098\|34\|NC_010511\|CRISPRCasFinder	6320098-6320131	34	NZ_CP032685	Rhizobium sp. CCGE531 plasmid pRCCGE531d, complete sequence	1182121-1182154	8	0.765
NC_010511_34	34.4\|6320098\|34\|NC_010511\|CRISPRCasFinder	6320098-6320131	34	NZ_CP032690	Rhizobium sp. CCGE532 plasmid pRCCGE532d, complete sequence	1183120-1183153	8	0.765
NC_010511_34	34.5\|6320165\|33\|NC_010511\|CRISPRCasFinder	6320165-6320197	33	NZ_AP022593	Mycolicibacterium arabiense strain JCM 18538 plasmid pJCM18538, complete sequence	719524-719556	8	0.758
NC_010511_34	34.7\|6320299\|34\|NC_010511\|CRISPRCasFinder	6320299-6320332	34	NC_004574	Ruegeria sp. PR1b plasmid pSD25, complete sequence	102061-102094	8	0.765
NC_010511_34	34.7\|6320299\|34\|NC_010511\|CRISPRCasFinder	6320299-6320332	34	NZ_CP030864	Streptomyces globosus strain LZH-48 plasmid unnamed2, complete sequence	242548-242581	8	0.765
NC_010511_34	34.7\|6320299\|34\|NC_010511\|CRISPRCasFinder	6320299-6320332	34	NZ_CP016613	Ralstonia solanacearum FJAT-91 plasmid unnamed1, complete sequence	725304-725337	8	0.765
NC_010511_34	34.7\|6320299\|34\|NC_010511\|CRISPRCasFinder	6320299-6320332	34	NZ_CP021449	Ralstonia solanacearum strain SEPPX05 plasmid pSEPPX05, complete sequence	1892667-1892700	8	0.765
NC_010511_34	34.7\|6320299\|34\|NC_010511\|CRISPRCasFinder	6320299-6320332	34	NZ_CP026091	Ralstonia solanacearum strain IBSBF 2570 plasmid unnamed, complete sequence	1835598-1835631	8	0.765
NC_010511_34	34.7\|6320299\|34\|NC_010511\|CRISPRCasFinder	6320299-6320332	34	NC_014309	Ralstonia solanacearum CFBP2957 plasmid RCFBPv3_mp, complete genome	2060230-2060263	8	0.765
NC_010511_34	34.7\|6320299\|34\|NC_010511\|CRISPRCasFinder	6320299-6320332	34	CP023013	Ralstonia solanacearum strain T110 plasmid unnamed, complete sequence	1905837-1905870	8	0.765
NC_010511_34	34.7\|6320299\|34\|NC_010511\|CRISPRCasFinder	6320299-6320332	34	NZ_CP021653	Ralstonia solanacearum strain RS 488 plasmid unnamed, complete sequence	1780032-1780065	8	0.765
NC_010511_34	34.7\|6320299\|34\|NC_010511\|CRISPRCasFinder	6320299-6320332	34	NZ_CP049790	Ralstonia solanacearum strain 202 plasmid unnamed, complete sequence	1930799-1930832	8	0.765
NC_010511_34	34.7\|6320299\|34\|NC_010511\|CRISPRCasFinder	6320299-6320332	34	NZ_CP049794	Ralstonia solanacearum strain 204 plasmid unnamed, complete sequence	741046-741079	8	0.765
NC_010511_34	34.7\|6320299\|34\|NC_010511\|CRISPRCasFinder	6320299-6320332	34	NZ_CP049788	Ralstonia solanacearum strain B2 plasmid unnamed, complete sequence	2026024-2026057	8	0.765
NC_010511_34	34.7\|6320299\|34\|NC_010511\|CRISPRCasFinder	6320299-6320332	34	NZ_CP022766	Ralstonia solanacearum strain T78 plasmid unnamed, complete sequence	1970362-1970395	8	0.765
NC_010511_34	34.7\|6320299\|34\|NC_010511\|CRISPRCasFinder	6320299-6320332	34	NZ_CP039340	Ralstonia solanacearum strain UW386 plasmid pUW386, complete sequence	1007061-1007094	8	0.765
NC_010511_34	34.7\|6320299\|34\|NC_010511\|CRISPRCasFinder	6320299-6320332	34	NZ_CP021763	Ralstonia pseudosolanacearum strain RS 476 plasmid unnamed, complete sequence	2003011-2003044	8	0.765
NC_010511_34	34.7\|6320299\|34\|NC_010511\|CRISPRCasFinder	6320299-6320332	34	NZ_CP026093	Ralstonia solanacearum strain SFC plasmid unnamed, complete sequence	1835753-1835786	8	0.765
NC_010511_34	34.7\|6320299\|34\|NC_010511\|CRISPRCasFinder	6320299-6320332	34	NZ_CP021767	Ralstonia solanacearum strain RS 489 plasmid unnamed, complete sequence	1780075-1780108	8	0.765
NC_010511_34	34.7\|6320299\|34\|NC_010511\|CRISPRCasFinder	6320299-6320332	34	NZ_CP015116	Ralstonia solanacearum strain EP1 plasmid unnamed, complete sequence	70083-70116	8	0.765
NC_010511_34	34.7\|6320299\|34\|NC_010511\|CRISPRCasFinder	6320299-6320332	34	NZ_CP016555	Ralstonia solanacearum FJAT-1458 plasmid plas1, complete sequence	1618386-1618419	8	0.765
NC_010511_34	34.7\|6320299\|34\|NC_010511\|CRISPRCasFinder	6320299-6320332	34	NZ_CP012940	Ralstonia solanacearum strain UW163 plasmid unnamed, complete sequence	185014-185047	8	0.765
NC_010511_34	34.7\|6320299\|34\|NC_010511\|CRISPRCasFinder	6320299-6320332	34	NZ_CP012944	Ralstonia solanacearum strain IBSBF1503 plasmid unnamed, complete sequence	96910-96943	8	0.765
NC_010511_34	34.7\|6320299\|34\|NC_010511\|CRISPRCasFinder	6320299-6320332	34	NZ_CP012688	Ralstonia solanacearum strain UY031 plasmid unnamed, complete sequence	1780030-1780063	8	0.765
NC_010511_34	34.7\|6320299\|34\|NC_010511\|CRISPRCasFinder	6320299-6320332	34	NZ_CP049792	Ralstonia solanacearum strain 203 plasmid unnamed, complete sequence	522522-522555	8	0.765
NC_010511_34	34.7\|6320299\|34\|NC_010511\|CRISPRCasFinder	6320299-6320332	34	NZ_CP052069	Ralstonia solanacearum strain FJAT91.F50 plasmid Plas1, complete sequence	1905607-1905640	8	0.765
NC_010511_34	34.7\|6320299\|34\|NC_010511\|CRISPRCasFinder	6320299-6320332	34	NZ_CP016915	Ralstonia solanacearum strain CQPS-1 plasmid unnamed, complete sequence	505432-505465	8	0.765
NC_010511_34	34.7\|6320299\|34\|NC_010511\|CRISPRCasFinder	6320299-6320332	34	NZ_CP016905	Ralstonia solanacearum strain KACC 10709 plasmid unnamed1	937428-937461	8	0.765
NC_010511_34	34.7\|6320299\|34\|NC_010511\|CRISPRCasFinder	6320299-6320332	34	NZ_CP025986	Ralstonia solanacearum strain RSCM plasmid p-unname2, complete sequence	398992-399025	8	0.765
NC_010511_34	34.7\|6320299\|34\|NC_010511\|CRISPRCasFinder	6320299-6320332	34	NZ_CP022769	Ralstonia solanacearum strain T60 plasmid unnamed, complete sequence	1978670-1978703	8	0.765
NC_010511_34	34.7\|6320299\|34\|NC_010511\|CRISPRCasFinder	6320299-6320332	34	NZ_CP015851	Ralstonia solanacearum strain YC40-M plasmid, complete sequence	491693-491726	8	0.765
NC_010511_34	34.7\|6320299\|34\|NC_010511\|CRISPRCasFinder	6320299-6320332	34	NZ_CP022773	Ralstonia solanacearum strain T42 plasmid unnamed, complete sequence	1688303-1688336	8	0.765
NC_010511_34	34.7\|6320299\|34\|NC_010511\|CRISPRCasFinder	6320299-6320332	34	NZ_CP022783	Ralstonia solanacearum strain SL3755 plasmid unnamed, complete sequence	1913268-1913301	8	0.765
NC_010511_34	34.7\|6320299\|34\|NC_010511\|CRISPRCasFinder	6320299-6320332	34	NZ_CP022791	Ralstonia solanacearum strain SL3103 plasmid unnamed, complete sequence	2036888-2036921	8	0.765
NC_010511_34	34.7\|6320299\|34\|NC_010511\|CRISPRCasFinder	6320299-6320332	34	NZ_CP022795	Ralstonia solanacearum strain SL2330 plasmid unnamed, complete sequence	1909294-1909327	8	0.765
NC_010511_34	34.7\|6320299\|34\|NC_010511\|CRISPRCasFinder	6320299-6320332	34	NZ_CP052071	Ralstonia solanacearum strain FJAT454.F1 plasmid Plas1, complete sequence	1981490-1981523	8	0.765
NC_010511_34	34.7\|6320299\|34\|NC_010511\|CRISPRCasFinder	6320299-6320332	34	NC_017575	Ralstonia solanacearum Po82 megaplasmid, complete sequence	1835250-1835283	8	0.765
NC_010511_34	34.7\|6320299\|34\|NC_010511\|CRISPRCasFinder	6320299-6320332	34	NZ_CP022482	Ralstonia solanacearum strain HA4-1 plasmid HA4-1MP, complete sequence	1178423-1178456	8	0.765
NC_010511_34	34.7\|6320299\|34\|NC_010511\|CRISPRCasFinder	6320299-6320332	34	NZ_CP009763	Ralstonia solanacearum OE1-1 plasmid unnamed, complete sequence	1846285-1846318	8	0.765
NC_010511_34	34.7\|6320299\|34\|NC_010511\|CRISPRCasFinder	6320299-6320332	34	CP023015	Ralstonia solanacearum strain T25 plasmid unnamed, complete sequence	1909474-1909507	8	0.765
NC_010511_34	34.7\|6320299\|34\|NC_010511\|CRISPRCasFinder	6320299-6320332	34	NZ_CP022779	Ralstonia solanacearum strain SL3882 plasmid unnamed, complete sequence	1990138-1990171	8	0.765
NC_010511_34	34.7\|6320299\|34\|NC_010511\|CRISPRCasFinder	6320299-6320332	34	NZ_CP052075	Ralstonia solanacearum strain FJAT448.F1 plasmid Plas1, complete sequence	1981457-1981490	8	0.765
NC_010511_34	34.7\|6320299\|34\|NC_010511\|CRISPRCasFinder	6320299-6320332	34	NZ_CP052085	Ralstonia solanacearum strain FJAT15353.F8 plasmid Plas1, complete sequence	1885477-1885510	8	0.765
NC_010511_34	34.7\|6320299\|34\|NC_010511\|CRISPRCasFinder	6320299-6320332	34	NZ_CP052095	Ralstonia solanacearum strain FJAT15340.F1 plasmid Plas1, complete sequence	1963047-1963080	8	0.765
NC_010511_34	34.7\|6320299\|34\|NC_010511\|CRISPRCasFinder	6320299-6320332	34	NZ_CP052105	Ralstonia solanacearum strain FJAT15252.F1 plasmid Plas1, complete sequence	1980200-1980233	8	0.765
NC_010511_34	34.7\|6320299\|34\|NC_010511\|CRISPRCasFinder	6320299-6320332	34	NZ_CP026308	Ralstonia solanacearum strain IBSBF 2571 plasmid unnamed, complete sequence	1835194-1835227	8	0.765
NC_010511_34	34.7\|6320299\|34\|NC_010511\|CRISPRCasFinder	6320299-6320332	34	NZ_CP021765	Ralstonia pseudosolanacearum strain CRMRs218 plasmid unnamed, complete sequence	2003037-2003070	8	0.765
NC_010511_34	34.7\|6320299\|34\|NC_010511\|CRISPRCasFinder	6320299-6320332	34	NZ_CP052077	Ralstonia solanacearum strain FJAT445.F50 plasmid Plas1, complete sequence	1885172-1885205	8	0.765
NC_010511_34	34.7\|6320299\|34\|NC_010511\|CRISPRCasFinder	6320299-6320332	34	NZ_CP052087	Ralstonia solanacearum strain FJAT15353.F50 plasmid Plas1, complete sequence	1885789-1885822	8	0.765
NC_010511_34	34.7\|6320299\|34\|NC_010511\|CRISPRCasFinder	6320299-6320332	34	NZ_CP052097	Ralstonia solanacearum strain FJAT15304.F6 plasmid Plas1, complete sequence	1963047-1963080	8	0.765
NC_010511_34	34.7\|6320299\|34\|NC_010511\|CRISPRCasFinder	6320299-6320332	34	CP047139	Ralstonia solanacearum strain CFBP 8695 plasmid unnamed, complete sequence	317805-317838	8	0.765
NC_010511_34	34.7\|6320299\|34\|NC_010511\|CRISPRCasFinder	6320299-6320332	34	NZ_CP051295	Ralstonia solanacearum strain CIAT_078 plasmid megaplasmid, complete sequence	184749-184782	8	0.765
NC_010511_34	34.7\|6320299\|34\|NC_010511\|CRISPRCasFinder	6320299-6320332	34	NZ_CP052115	Ralstonia solanacearum strain FJAT1463.F50 plasmid Plas1, complete sequence	1980299-1980332	8	0.765
NC_010511_34	34.7\|6320299\|34\|NC_010511\|CRISPRCasFinder	6320299-6320332	34	NZ_CP052127	Ralstonia solanacearum strain FJAT1303.F50 plasmid Plas1, complete sequence	1885477-1885510	8	0.765
NC_010511_34	34.7\|6320299\|34\|NC_010511\|CRISPRCasFinder	6320299-6320332	34	CP047137	Ralstonia solanacearum strain CFBP 8697 plasmid unnamed, complete sequence	298143-298176	8	0.765
NC_010511_34	34.7\|6320299\|34\|NC_010511\|CRISPRCasFinder	6320299-6320332	34	NZ_CP052079	Ralstonia solanacearum strain FJAT445.F1 plasmid Plas1, complete sequence	1885821-1885854	8	0.765
NC_010511_34	34.7\|6320299\|34\|NC_010511\|CRISPRCasFinder	6320299-6320332	34	NZ_CP052089	Ralstonia solanacearum strain FJAT15353.F1 plasmid Plas1, complete sequence	1884680-1884713	8	0.765
NC_010511_34	34.7\|6320299\|34\|NC_010511\|CRISPRCasFinder	6320299-6320332	34	NZ_CP052093	Ralstonia solanacearum strain FJAT15340.F50 plasmid Plas1, complete sequence	1963047-1963080	8	0.765
NC_010511_34	34.7\|6320299\|34\|NC_010511\|CRISPRCasFinder	6320299-6320332	34	NZ_CP052101	Ralstonia solanacearum strain FJAT15304.F1 plasmid Plas1, complete sequence	1963047-1963080	8	0.765
NC_010511_34	34.7\|6320299\|34\|NC_010511\|CRISPRCasFinder	6320299-6320332	34	NZ_CP052099	Ralstonia solanacearum strain FJAT15304.F50 plasmid Plas1, complete sequence	1963047-1963080	8	0.765
NC_010511_34	34.7\|6320299\|34\|NC_010511\|CRISPRCasFinder	6320299-6320332	34	NZ_CP052107	Ralstonia solanacearum strain FJAT15249.F50 plasmid Plas1, complete sequence	1980295-1980328	8	0.765
NC_010511_34	34.7\|6320299\|34\|NC_010511\|CRISPRCasFinder	6320299-6320332	34	NZ_CP022781	Ralstonia solanacearum strain SL3822 plasmid unnamed, complete sequence	2041999-2042032	8	0.765
NC_010511_34	34.7\|6320299\|34\|NC_010511\|CRISPRCasFinder	6320299-6320332	34	NZ_CP052117	Ralstonia solanacearum strain FJAT1463.F1 plasmid Plas1, complete sequence	1980284-1980317	8	0.765
NC_010511_34	34.7\|6320299\|34\|NC_010511\|CRISPRCasFinder	6320299-6320332	34	NZ_CP052125	Ralstonia solanacearum strain FJAT1452.F1 plasmid Plas1, complete sequence	1885197-1885230	8	0.765
NC_010511_34	34.7\|6320299\|34\|NC_010511\|CRISPRCasFinder	6320299-6320332	34	NZ_CP022793	Ralstonia solanacearum strain SL2729 plasmid unnamed, complete sequence	1896247-1896280	8	0.765
NC_010511_34	34.7\|6320299\|34\|NC_010511\|CRISPRCasFinder	6320299-6320332	34	NZ_CP022785	Ralstonia solanacearum strain SL3730 plasmid unnamed, complete sequence	1876881-1876914	8	0.765
NC_010511_34	34.7\|6320299\|34\|NC_010511\|CRISPRCasFinder	6320299-6320332	34	NZ_CP022787	Ralstonia solanacearum strain SL3300 plasmid unnamed, complete sequence	1939473-1939506	8	0.765
NC_010511_34	34.7\|6320299\|34\|NC_010511\|CRISPRCasFinder	6320299-6320332	34	NZ_CP022756	Ralstonia solanacearum strain T117 plasmid unnamed, complete sequence	1967899-1967932	8	0.765
NC_010511_34	34.7\|6320299\|34\|NC_010511\|CRISPRCasFinder	6320299-6320332	34	NZ_CP052129	Ralstonia solanacearum strain FJAT1303.F1 plasmid Plas1, complete sequence	1960362-1960395	8	0.765
NC_010511_34	34.7\|6320299\|34\|NC_010511\|CRISPRCasFinder	6320299-6320332	34	NZ_CP052121	Ralstonia solanacearum strain FJAT1458.F1 plasmid Plas1, complete sequence	1980284-1980317	8	0.765
NC_010511_34	34.7\|6320299\|34\|NC_010511\|CRISPRCasFinder	6320299-6320332	34	NZ_CP052123	Ralstonia solanacearum strain FJAT1452.F50 plasmid Plas1, complete sequence	1885197-1885230	8	0.765
NC_010511_34	34.7\|6320299\|34\|NC_010511\|CRISPRCasFinder	6320299-6320332	34	NZ_CP052131	Ralstonia solanacearum strain FJAT1303.F8 plasmid Plas1, complete sequence	1885788-1885821	8	0.765
NC_010511_34	34.7\|6320299\|34\|NC_010511\|CRISPRCasFinder	6320299-6320332	34	CP011998	Ralstonia solanacearum strain YC45 plasmid, complete sequence	1928115-1928148	8	0.765
NC_010511_34	34.7\|6320299\|34\|NC_010511\|CRISPRCasFinder	6320299-6320332	34	NZ_CP052073	Ralstonia solanacearum strain FJAT448.F50 plasmid Plas1, complete sequence	1981280-1981313	8	0.765
NC_010511_34	34.7\|6320299\|34\|NC_010511\|CRISPRCasFinder	6320299-6320332	34	NZ_CP052081	Ralstonia solanacearum strain FJAT442.F50 plasmid Plas1, complete sequence	1885197-1885230	8	0.765
NC_010511_34	34.7\|6320299\|34\|NC_010511\|CRISPRCasFinder	6320299-6320332	34	NZ_CP052083	Ralstonia solanacearum strain FJAT442.F1 plasmid Plas1, complete sequence	1885197-1885230	8	0.765
NC_010511_34	34.7\|6320299\|34\|NC_010511\|CRISPRCasFinder	6320299-6320332	34	NZ_CP052109	Ralstonia solanacearum strain FJAT15249.F1 plasmid Plas1, complete sequence	1980295-1980328	8	0.765
NC_010511_34	34.7\|6320299\|34\|NC_010511\|CRISPRCasFinder	6320299-6320332	34	NZ_CP052091	Ralstonia solanacearum strain FJAT15340.F6 plasmid Plas1, complete sequence	1963052-1963085	8	0.765
NC_010511_34	34.7\|6320299\|34\|NC_010511\|CRISPRCasFinder	6320299-6320332	34	NZ_CP052111	Ralstonia solanacearum strain FJAT15244.F50 plasmid Plas1, complete sequence	2039984-2040017	8	0.765
NC_010511_34	34.7\|6320299\|34\|NC_010511\|CRISPRCasFinder	6320299-6320332	34	NZ_CP052103	Ralstonia solanacearum strain FJAT15252.F50 plasmid Plas1, complete sequence	1980306-1980339	8	0.765
NC_010511_34	34.7\|6320299\|34\|NC_010511\|CRISPRCasFinder	6320299-6320332	34	NZ_CP052119	Ralstonia solanacearum strain FJAT1458.F50 plasmid Plas1, complete sequence	1980107-1980140	8	0.765
NC_010511_34	34.7\|6320299\|34\|NC_010511\|CRISPRCasFinder	6320299-6320332	34	NZ_CP052113	Ralstonia solanacearum strain FJAT15244.F1 plasmid Plas1, complete sequence	2039984-2040017	8	0.765
NC_010511_34	34.7\|6320299\|34\|NC_010511\|CRISPRCasFinder	6320299-6320332	34	KT021004	Thermobifida phage P1312, complete genome	53841-53874	8	0.765
NC_010511_34	34.15\|6320843\|34\|NC_010511\|CRISPRCasFinder	6320843-6320876	34	NZ_CP043960	Streptomyces tendae strain 139 plasmid unnamed1, complete sequence	76795-76828	8	0.765
NC_010511_6	6.1\|725596\|32\|NC_010511\|CRISPRCasFinder	725596-725627	32	NZ_CP024582	Roseomonas sp. FDAARGOS_362 plasmid unnamed1, complete sequence	76064-76095	9	0.719
NC_010511_6	6.1\|725596\|32\|NC_010511\|CRISPRCasFinder	725596-725627	32	NZ_CP021028	Rhizobium sp. TAL182 plasmid pRetTAL182d, complete sequence	134621-134652	9	0.719
NC_010511_6	6.1\|725596\|32\|NC_010511\|CRISPRCasFinder	725596-725627	32	NZ_CP013503	Rhizobium esperanzae strain N561 plasmid pRspN561c, complete sequence	130786-130817	9	0.719
NC_010511_6	6.1\|725596\|32\|NC_010511\|CRISPRCasFinder	725596-725627	32	NZ_CP013509	Rhizobium sp. N1341 plasmid pRspN1341d, complete sequence	130786-130817	9	0.719
NC_010511_6	6.1\|725596\|32\|NC_010511\|CRISPRCasFinder	725596-725627	32	NZ_CP013520	Rhizobium sp. N113 plasmid pRspN113c, complete sequence	130786-130817	9	0.719
NC_010511_6	6.1\|725596\|32\|NC_010511\|CRISPRCasFinder	725596-725627	32	NZ_CP013493	Rhizobium sp. N6212 plasmid pRspN6212c, complete sequence	130786-130817	9	0.719
NC_010511_6	6.1\|725596\|32\|NC_010511\|CRISPRCasFinder	725596-725627	32	NZ_CP013516	Rhizobium sp. N1314 plasmid pRspN1314e, complete sequence	131234-131265	9	0.719
NC_010511_6	6.1\|725596\|32\|NC_010511\|CRISPRCasFinder	725596-725627	32	NZ_CP023068	Ensifer sojae CCBAU 05684 plasmid pSJ05684b, complete sequence	530707-530738	9	0.719
NC_010511_11	11.5\|1944081\|34\|NC_010511\|PILER-CR,CRISPRCasFinder,CRT	1944081-1944114	34	NZ_CP054616	Azospirillum oryzae strain KACC 14407 plasmid unnamed2, complete sequence	518063-518096	9	0.735
NC_010511_14	14.2\|2625230\|34\|NC_010511\|PILER-CR,CRISPRCasFinder,CRT	2625230-2625263	34	NZ_CP016365	Phaeobacter porticola strain P97 plasmid pP97_a, complete sequence	64781-64814	9	0.735
NC_010511_17	17.1\|3091259\|31\|NC_010511\|CRISPRCasFinder	3091259-3091289	31	NC_021289	Burkholderia insecticola plasmid p1, complete sequence	99448-99478	9	0.71
NC_010511_28	28.1\|4448455\|35\|NC_010511\|CRISPRCasFinder	4448455-4448489	35	NZ_AP014705	Methylobacterium aquaticum strain MA-22A plasmid pMaq22A_1p, complete sequence	995753-995787	9	0.743
NC_010511_34	34.1\|6319896\|34\|NC_010511\|CRISPRCasFinder	6319896-6319929	34	NZ_CP006990	Rhizobium sp. IE4771 plasmid pRetIE4771d, complete sequence	487024-487057	9	0.735
NC_010511_34	34.7\|6320299\|34\|NC_010511\|CRISPRCasFinder	6320299-6320332	34	MH588547	Caulobacter phage CcrSC, complete genome	230973-231006	9	0.735
NC_010511_34	34.7\|6320299\|34\|NC_010511\|CRISPRCasFinder	6320299-6320332	34	NC_016591	Burkholderia sp. YI23 plasmid byi_2p, complete sequence	208885-208918	9	0.735
NC_010511_34	34.7\|6320299\|34\|NC_010511\|CRISPRCasFinder	6320299-6320332	34	NZ_CP010418	Azotobacter chroococcum NCIMB 8003 plasmid pAcX50c, complete sequence	2689-2722	9	0.735
NC_010511_34	34.7\|6320299\|34\|NC_010511\|CRISPRCasFinder	6320299-6320332	34	NC_013855	Azospirillum sp. B510 plasmid pAB510a, complete sequence	1008901-1008934	9	0.735
NC_010511_34	34.7\|6320299\|34\|NC_010511\|CRISPRCasFinder	6320299-6320332	34	NZ_MF996511	Bacillus glycinifermentans strain KBN06P03352 plasmid unnamed3, complete sequence	3107-3140	9	0.735
NC_010511_34	34.9\|6320433\|35\|NC_010511\|CRISPRCasFinder	6320433-6320467	35	NZ_HG938356	Neorhizobium galegae bv. officinalis bv. officinalis str. HAMBI 1141 plasmid pHAMBI1141a, complete sequence	1467522-1467556	9	0.743
NC_010511_34	34.14\|6320775\|35\|NC_010511\|CRISPRCasFinder	6320775-6320809	35	NZ_CP029588	Klebsiella pneumoniae strain DA33141 plasmid pDA33141-217, complete sequence	188163-188197	9	0.743
NC_010511_34	34.14\|6320775\|35\|NC_010511\|CRISPRCasFinder	6320775-6320809	35	NZ_CP036302	Klebsiella pneumoniae subsp. pneumoniae strain WCHKP015093 plasmid p1_015093, complete sequence	178897-178931	9	0.743
NC_010511_34	34.14\|6320775\|35\|NC_010511\|CRISPRCasFinder	6320775-6320809	35	CP052405	Klebsiella pneumoniae strain C17KP0020 plasmid pC17KP0020-1, complete sequence	208831-208865	9	0.743
NC_010511_34	34.14\|6320775\|35\|NC_010511\|CRISPRCasFinder	6320775-6320809	35	NZ_CP041949	Klebsiella pneumoniae strain KP2 plasmid pKP2_3, complete sequence	149878-149912	9	0.743
NC_010511_34	34.14\|6320775\|35\|NC_010511\|CRISPRCasFinder	6320775-6320809	35	CP052218	Klebsiella pneumoniae strain E17KP0053 plasmid pE17KP0053-1, complete sequence	178375-178409	9	0.743
NC_010511_34	34.14\|6320775\|35\|NC_010511\|CRISPRCasFinder	6320775-6320809	35	NZ_CP036337	Klebsiella pneumoniae strain BP327 plasmid pIncFIBK, complete sequence	94176-94210	9	0.743
NC_010511_34	34.14\|6320775\|35\|NC_010511\|CRISPRCasFinder	6320775-6320809	35	NZ_CP039809	Klebsiella pneumoniae strain C2660 plasmid pC2660-2, complete sequence	178897-178931	9	0.743
NC_010511_34	34.14\|6320775\|35\|NC_010511\|CRISPRCasFinder	6320775-6320809	35	NZ_CP033402	Klebsiella pneumoniae strain WCHKP115069 plasmid p1_115069, complete sequence	181533-181567	9	0.743
NC_010511_34	34.14\|6320775\|35\|NC_010511\|CRISPRCasFinder	6320775-6320809	35	NZ_CP029830	Azospirillum ramasamyi strain M2T2B2 plasmid unnamed1, complete sequence	377389-377423	9	0.743
NC_010511_34	34.14\|6320775\|35\|NC_010511\|CRISPRCasFinder	6320775-6320809	35	NZ_CP029387	Klebsiella pneumoniae subsp. pneumoniae strain SCKP040074 plasmid pTetD_040074, complete sequence	200355-200389	9	0.743
NC_010511_34	34.14\|6320775\|35\|NC_010511\|CRISPRCasFinder	6320775-6320809	35	NZ_LR025093	Klebsiella pneumoniae isolate KP9201 plasmid 2, complete sequence	78322-78356	9	0.743
NC_010511_34	34.14\|6320775\|35\|NC_010511\|CRISPRCasFinder	6320775-6320809	35	NZ_CP042883	Klebsiella pneumoniae strain NMBU-W07E18 plasmid pNMBU-W07E18_01, complete sequence	170011-170045	9	0.743
NC_010511_34	34.14\|6320775\|35\|NC_010511\|CRISPRCasFinder	6320775-6320809	35	CP052435	Klebsiella pneumoniae strain C16KP0108 plasmid pC16KP0108-1, complete sequence	125632-125666	9	0.743
NC_010511_34	34.14\|6320775\|35\|NC_010511\|CRISPRCasFinder	6320775-6320809	35	NZ_LT994840	Klebsiella pneumoniae isolate CNR48 plasmid CNR48, complete sequence	63678-63712	9	0.743
NC_010511_34	34.14\|6320775\|35\|NC_010511\|CRISPRCasFinder	6320775-6320809	35	NZ_CP041928	Klebsiella pneumoniae strain 18-2374 plasmid pSECR18-2374A, complete sequence	132384-132418	9	0.743
NC_010511_34	34.14\|6320775\|35\|NC_010511\|CRISPRCasFinder	6320775-6320809	35	NC_023332	Klebsiella pneumoniae strain ST48 plasmid pKP09085, complete sequence	94535-94569	9	0.743
NC_010511_34	34.14\|6320775\|35\|NC_010511\|CRISPRCasFinder	6320775-6320809	35	NC_023333	Klebsiella pneumoniae strain ST23 plasmid pKP007, complete sequence	97423-97457	9	0.743
NC_010511_34	34.14\|6320775\|35\|NC_010511\|CRISPRCasFinder	6320775-6320809	35	NC_023334	Klebsiella pneumoniae strain ST15 plasmid pKP02022, complete sequence	96764-96798	9	0.743
NC_010511_34	34.14\|6320775\|35\|NC_010511\|CRISPRCasFinder	6320775-6320809	35	NZ_CP029591	Klebsiella pneumoniae strain DA33144 plasmid pDA33144-220, complete sequence	183907-183941	9	0.743
NC_010511_34	34.14\|6320775\|35\|NC_010511\|CRISPRCasFinder	6320775-6320809	35	NC_016966	Klebsiella pneumoniae plasmid pUUH239.2, complete sequence	97018-97052	9	0.743
NC_010511_34	34.14\|6320775\|35\|NC_010511\|CRISPRCasFinder	6320775-6320809	35	NZ_CP012572	Klebsiella pneumoniae strain UCLAOXA232KP plasmid pUCLAOXA232-6.X, complete sequence	27044-27078	9	0.743
NC_010511_34	34.14\|6320775\|35\|NC_010511\|CRISPRCasFinder	6320775-6320809	35	NZ_CP041640	Klebsiella pneumoniae strain PIMB15ND2KP27 plasmid pKP27-MPH, complete sequence	89584-89618	9	0.743
NC_010511_34	34.14\|6320775\|35\|NC_010511\|CRISPRCasFinder	6320775-6320809	35	NZ_CP012567	Klebsiella pneumoniae strain UCLAOXA232KP plasmid pUCLAOXA232-6, complete sequence	27043-27077	9	0.743
NC_010511_34	34.14\|6320775\|35\|NC_010511\|CRISPRCasFinder	6320775-6320809	35	NZ_CP050379	Klebsiella pneumoniae strain 51015 plasmid p51015_CTX_M_15, complete sequence	138174-138208	9	0.743
NC_010511_34	34.14\|6320775\|35\|NC_010511\|CRISPRCasFinder	6320775-6320809	35	NZ_CP050374	Klebsiella pneumoniae strain 50595 plasmid p50595_NDM_1, complete sequence	161722-161756	9	0.743
NC_010511_34	34.14\|6320775\|35\|NC_010511\|CRISPRCasFinder	6320775-6320809	35	NZ_CP020903	Klebsiella pneumoniae strain K66-45 plasmid pK66-45-2, complete sequence	123271-123305	9	0.743
NC_010511_34	34.14\|6320775\|35\|NC_010511\|CRISPRCasFinder	6320775-6320809	35	NZ_CP032186	Klebsiella pneumoniae strain AR_0075 plasmid unnamed1, complete sequence	179359-179393	9	0.743
NC_010511_34	34.14\|6320775\|35\|NC_010511\|CRISPRCasFinder	6320775-6320809	35	NZ_LR025089	Klebsiella pneumoniae isolate KP980 plasmid 2, complete sequence	219184-219218	9	0.743
NC_010511_34	34.14\|6320775\|35\|NC_010511\|CRISPRCasFinder	6320775-6320809	35	NZ_CP036188	Klebsiella pneumoniae strain BA1559 plasmid pIncFIBK, complete sequence	109803-109837	9	0.743
NC_010511_34	34.14\|6320775\|35\|NC_010511\|CRISPRCasFinder	6320775-6320809	35	NZ_MN268580	Klebsiella pneumoniae strain KP13-53 plasmid pKP13-53-tet(A), complete sequence	87993-88027	9	0.743
NC_010511_34	34.14\|6320775\|35\|NC_010511\|CRISPRCasFinder	6320775-6320809	35	NC_013858	Azospirillum sp. B510 plasmid pAB510d, complete sequence	260289-260323	9	0.743
NC_010511_34	34.23\|6320293\|40\|NC_010511\|CRT,PILER-CR	6320293-6320332	40	NZ_CP025613	Niveispirillum cyanobacteriorum strain TH16 plasmid unnamed1, complete sequence	243122-243161	9	0.775
NC_010511_11	11.4\|1944015\|35\|NC_010511\|PILER-CR,CRISPRCasFinder,CRT	1944015-1944049	35	NZ_CP034352	Streptomyces sp. W1SF4 plasmid p2, complete sequence	208350-208384	10	0.714
NC_010511_24	24.1\|4168034\|33\|NC_010511\|CRISPRCasFinder	4168034-4168066	33	NC_011892	Methylobacterium nodulans ORS 2060 plasmid pMNOD01, complete sequence	135552-135584	10	0.697
NC_010511_34	34.5\|6320165\|33\|NC_010511\|CRISPRCasFinder	6320165-6320197	33	NZ_CP032346	Azospirillum brasilense strain MTCC4039 plasmid p1, complete sequence	286486-286518	10	0.697
NC_010511_34	34.7\|6320299\|34\|NC_010511\|CRISPRCasFinder	6320299-6320332	34	NC_013856	Azospirillum sp. B510 plasmid pAB510b, complete sequence	506579-506612	10	0.706
NC_010511_34	34.7\|6320299\|34\|NC_010511\|CRISPRCasFinder	6320299-6320332	34	NC_016586	Azospirillum lipoferum 4B plasmid AZO_p2, complete sequence	545046-545079	10	0.706
NC_010511_34	34.7\|6320299\|34\|NC_010511\|CRISPRCasFinder	6320299-6320332	34	NC_018022	Mycolicibacterium chubuense NBB4 plasmid pMYCCH.01, complete sequence	380884-380917	10	0.706
NC_010511_34	34.7\|6320299\|34\|NC_010511\|CRISPRCasFinder	6320299-6320332	34	NZ_CP015867	Streptomyces parvulus strain 2297 plasmid pSPA1, complete sequence	88063-88096	10	0.706
NC_010511_34	34.7\|6320299\|34\|NC_010511\|CRISPRCasFinder	6320299-6320332	34	NZ_CP029092	Pseudomonas aeruginosa strain AR441 plasmid unnamed2, complete sequence	30594-30627	10	0.706
NC_010511_34	34.7\|6320299\|34\|NC_010511\|CRISPRCasFinder	6320299-6320332	34	NZ_CP027168	Pseudomonas aeruginosa strain AR_0356 plasmid unnamed1, complete sequence	2037-2070	10	0.706
NC_010511_34	34.7\|6320299\|34\|NC_010511\|CRISPRCasFinder	6320299-6320332	34	NZ_AP014579	Burkholderia sp. RPE67 plasmid p1, complete sequence	671247-671280	10	0.706
NC_010511_34	34.14\|6320775\|35\|NC_010511\|CRISPRCasFinder	6320775-6320809	35	NZ_CP054842	Acidovorax sp. 16-35-5 plasmid unnamed2, complete sequence	101749-101783	10	0.714
NC_010511_34	34.16\|6320910\|35\|NC_010511\|CRISPRCasFinder	6320910-6320944	35	NC_016586	Azospirillum lipoferum 4B plasmid AZO_p2, complete sequence	293098-293132	10	0.714
NC_010511_11	11.4\|1944015\|35\|NC_010511\|PILER-CR,CRISPRCasFinder,CRT	1944015-1944049	35	NC_017957	Tistrella mobilis KA081020-065 plasmid pTM1, complete sequence	124493-124527	11	0.686
NC_010511_11	11.5\|1944081\|34\|NC_010511\|PILER-CR,CRISPRCasFinder,CRT	1944081-1944114	34	NZ_CP054606	Sulfitobacter pseudonitzschiae strain H46 plasmid unnamed7, complete sequence	231287-231320	11	0.676
NC_010511_11	11.5\|1944081\|34\|NC_010511\|PILER-CR,CRISPRCasFinder,CRT	1944081-1944114	34	NZ_CP020399	Burkholderia multivorans strain FDAARGOS_246 plasmid unnamed, complete sequence	160402-160435	11	0.676
NC_010511_34	34.7\|6320299\|34\|NC_010511\|CRISPRCasFinder	6320299-6320332	34	NC_017791	Deinococcus gobiensis I-0 plasmid P2, complete sequence	70787-70820	11	0.676

1. spacer 26.1|4322290|25|NC_010511|CRISPRCasFinder matches to NZ_CP023068 (Ensifer sojae CCBAU 05684 plasmid pSJ05684b, complete sequence) position: , mismatch: 4, identity: 0.84

ttcccggtaccggaagtggtggtac	CRISPR spacer
ttcccggtaacggaaatggtggtgg	Protospacer
********* *****.*******.

2. spacer 22.1|3951416|26|NC_010511|CRISPRCasFinder matches to NZ_CP042265 (Litoreibacter sp. LN3S51 plasmid unnamed4, complete sequence) position: , mismatch: 5, identity: 0.808

tctgacaagcccgcgcggcgcgtgag	CRISPR spacer
acgcgcaagcccgcgcggcgggtgag	Protospacer
 *  .*************** *****

3. spacer 22.1|3951416|26|NC_010511|CRISPRCasFinder matches to NZ_CP016462 (Blastomonas sp. RAC04 plasmid pBSY18_1, complete sequence) position: , mismatch: 5, identity: 0.808

tctgacaagcccgcgcggcgcgtgag	CRISPR spacer
ttggcgcagcccgcgcggcgcgtgag	Protospacer
*. *   *******************

4. spacer 22.1|3951416|26|NC_010511|CRISPRCasFinder matches to NZ_AP022319 (Burkholderia sp. THE68 plasmid BTHE68_p1, complete sequence) position: , mismatch: 5, identity: 0.808

tctgacaagcccgcgcggcgcgtgag	CRISPR spacer
caggacaagcccgagcagcgcgtgag	Protospacer
.  ********** **.*********

5. spacer 26.1|4322290|25|NC_010511|CRISPRCasFinder matches to NZ_CP018654 (Salmonella enterica subsp. enterica serovar Enteritidis strain 81-1705 plasmid pSE81-1705-3, complete sequence) position: , mismatch: 5, identity: 0.8

ttcccggtaccggaagtggtggtac	CRISPR spacer
gaaccggtaccggaagtggtggtga	Protospacer
   ********************.

6. spacer 34.16|6320910|35|NC_010511|CRISPRCasFinder matches to KR063279 (Gordonia phage GMA3, complete genome) position: , mismatch: 6, identity: 0.829

ccgcccg-cgcccgtcgcgcgccacgcggtgtcggc	CRISPR spacer
-cgccggtcgccggtcgcgcgccacgcggtatcgcg	Protospacer
 **** * **** *****************.***

7. spacer 36.1|6830766|29|NC_010511|CRISPRCasFinder matches to NZ_CP044217 (Mesorhizobium sp. NIBRBAC000500504 plasmid unnamed, complete sequence) position: , mismatch: 6, identity: 0.793

gaagccatcaaccggatgtcggatgacac	CRISPR spacer
cgcgccagcaaccggatgccggatgaccc	Protospacer
 . **** **********.******** *

8. spacer 6.1|725596|32|NC_010511|CRISPRCasFinder matches to NC_017793 (Deinococcus gobiensis I-0 plasmid P6, complete sequence) position: , mismatch: 7, identity: 0.781

gatgaagacgaccggcagcgtcaagggcacct	CRISPR spacer
ggccacgacgagcggcagcgtcaagggcacgc	Protospacer
*.. * ***** ****************** .

9. spacer 6.1|725596|32|NC_010511|CRISPRCasFinder matches to NZ_CP049244 (Rhizobium pseudoryzae strain DSM 19479 plasmid unnamed3, complete sequence) position: , mismatch: 7, identity: 0.781

gatgaagacgaccggcagcgtcaagggcacct	CRISPR spacer
gatgaagacgaccggcagcttccagatggccg	Protospacer
******************* ** **.  .**

10. spacer 6.1|725596|32|NC_010511|CRISPRCasFinder matches to NZ_CP015740 (Shinella sp. HZN7 plasmid pShin-04, complete sequence) position: , mismatch: 7, identity: 0.781

gatgaagacgaccggcagcgtcaagggcacct	CRISPR spacer
cacgaagacgaccggcagcttcatgggccacg	Protospacer
 *.**************** *** ****  *

11. spacer 6.1|725596|32|NC_010511|CRISPRCasFinder matches to NZ_LR594664 (Variovorax sp. RA8 plasmid 3) position: , mismatch: 7, identity: 0.781

gatgaagacgaccggcagcgtcaagggcacct	CRISPR spacer
gatgaagaccaccggaagcgtcatcgtccccg	Protospacer
********* ***** *******  * * **

12. spacer 11.4|1944015|35|NC_010511|PILER-CR,CRISPRCasFinder,CRT matches to NC_022043 (Paracoccus aminophilus JCM 7686 plasmid pAMI5, complete sequence) position: , mismatch: 7, identity: 0.8

aaggcgaccgtgcccgcgatcatcgaggtgcggtg	CRISPR spacer
aaaaagaccctgcccgcgatcatcgatgtgcgcgg	Protospacer
**.. **** **************** *****  *

13. spacer 11.5|1944081|34|NC_010511|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP003988 (Streptomyces sp. 769 plasmid pSGZL, complete sequence) position: , mismatch: 7, identity: 0.794

gccgtcggcgcctggtcgctgcccgg-cgacacgc	CRISPR spacer
tcggtcggcgctgggtcgctgcccggccgaggcg-	Protospacer
 * ********. ************* *** .**

14. spacer 34.4|6320098|34|NC_010511|CRISPRCasFinder matches to NZ_CP016613 (Ralstonia solanacearum FJAT-91 plasmid unnamed1, complete sequence) position: , mismatch: 7, identity: 0.794

cggtcgggtccccgaacagatccgcctcgaccag	CRISPR spacer
cgcgctcgaccccgaacagctccgcctccaccag	Protospacer
**  *  * ********** ******** *****

15. spacer 34.4|6320098|34|NC_010511|CRISPRCasFinder matches to NZ_CP021449 (Ralstonia solanacearum strain SEPPX05 plasmid pSEPPX05, complete sequence) position: , mismatch: 7, identity: 0.794

cggtcgggtccccgaacagatccgcctcgaccag	CRISPR spacer
cgcgctcgaccccgaacagctccgcctccaccag	Protospacer
**  *  * ********** ******** *****

16. spacer 34.4|6320098|34|NC_010511|CRISPRCasFinder matches to CP023013 (Ralstonia solanacearum strain T110 plasmid unnamed, complete sequence) position: , mismatch: 7, identity: 0.794

cggtcgggtccccgaacagatccgcctcgaccag	CRISPR spacer
cgcgctcgaccccgaacagctccgcctccaccag	Protospacer
**  *  * ********** ******** *****

17. spacer 34.4|6320098|34|NC_010511|CRISPRCasFinder matches to NZ_CP049790 (Ralstonia solanacearum strain 202 plasmid unnamed, complete sequence) position: , mismatch: 7, identity: 0.794

cggtcgggtccccgaacagatccgcctcgaccag	CRISPR spacer
cgcgctcgaccccgaacagctccgcctccaccag	Protospacer
**  *  * ********** ******** *****

18. spacer 34.4|6320098|34|NC_010511|CRISPRCasFinder matches to NZ_CP049794 (Ralstonia solanacearum strain 204 plasmid unnamed, complete sequence) position: , mismatch: 7, identity: 0.794

cggtcgggtccccgaacagatccgcctcgaccag	CRISPR spacer
cgcgctcgaccccgaacagctccgcctccaccag	Protospacer
**  *  * ********** ******** *****

19. spacer 34.4|6320098|34|NC_010511|CRISPRCasFinder matches to NZ_CP049788 (Ralstonia solanacearum strain B2 plasmid unnamed, complete sequence) position: , mismatch: 7, identity: 0.794

cggtcgggtccccgaacagatccgcctcgaccag	CRISPR spacer
cgcgctcgaccccgaacagctccgcctccaccag	Protospacer
**  *  * ********** ******** *****

20. spacer 34.4|6320098|34|NC_010511|CRISPRCasFinder matches to NZ_CP022766 (Ralstonia solanacearum strain T78 plasmid unnamed, complete sequence) position: , mismatch: 7, identity: 0.794

cggtcgggtccccgaacagatccgcctcgaccag	CRISPR spacer
cgcgctcgaccccgaacagctccgcctccaccag	Protospacer
**  *  * ********** ******** *****

21. spacer 34.4|6320098|34|NC_010511|CRISPRCasFinder matches to NZ_CP018784 (Curtobacterium pusillum strain AA3 plasmid pCPAA3, complete sequence) position: , mismatch: 7, identity: 0.794

--cggtcgggtccccgaacagatccgcctcgaccag	CRISPR spacer
actgctc--gtcgccgtacagatccgcctcgacctg	Protospacer
  .* **  *** *** ***************** *

22. spacer 34.4|6320098|34|NC_010511|CRISPRCasFinder matches to NZ_CP021763 (Ralstonia pseudosolanacearum strain RS 476 plasmid unnamed, complete sequence) position: , mismatch: 7, identity: 0.794

cggtcgggtccccgaacagatccgcctcgaccag	CRISPR spacer
cgcgctcgaccccgaacagctccgcctccaccag	Protospacer
**  *  * ********** ******** *****

23. spacer 34.4|6320098|34|NC_010511|CRISPRCasFinder matches to NZ_CP015116 (Ralstonia solanacearum strain EP1 plasmid unnamed, complete sequence) position: , mismatch: 7, identity: 0.794

cggtcgggtccccgaacagatccgcctcgaccag	CRISPR spacer
cgcgctcgaccccgaacagctccgcctccaccag	Protospacer
**  *  * ********** ******** *****

24. spacer 34.4|6320098|34|NC_010511|CRISPRCasFinder matches to NZ_CP016555 (Ralstonia solanacearum FJAT-1458 plasmid plas1, complete sequence) position: , mismatch: 7, identity: 0.794

cggtcgggtccccgaacagatccgcctcgaccag	CRISPR spacer
cgcgctcgaccccgaacagctccgcctccaccag	Protospacer
**  *  * ********** ******** *****

25. spacer 34.4|6320098|34|NC_010511|CRISPRCasFinder matches to NZ_CP049792 (Ralstonia solanacearum strain 203 plasmid unnamed, complete sequence) position: , mismatch: 7, identity: 0.794

cggtcgggtccccgaacagatccgcctcgaccag	CRISPR spacer
cgcgctcgaccccgaacagctccgcctccaccag	Protospacer
**  *  * ********** ******** *****

26. spacer 34.4|6320098|34|NC_010511|CRISPRCasFinder matches to NZ_CP052069 (Ralstonia solanacearum strain FJAT91.F50 plasmid Plas1, complete sequence) position: , mismatch: 7, identity: 0.794

cggtcgggtccccgaacagatccgcctcgaccag	CRISPR spacer
cgcgctcgaccccgaacagctccgcctccaccag	Protospacer
**  *  * ********** ******** *****

27. spacer 34.4|6320098|34|NC_010511|CRISPRCasFinder matches to NZ_CP016915 (Ralstonia solanacearum strain CQPS-1 plasmid unnamed, complete sequence) position: , mismatch: 7, identity: 0.794

cggtcgggtccccgaacagatccgcctcgaccag	CRISPR spacer
cgcgctcgaccccgaacagctccgcctccaccag	Protospacer
**  *  * ********** ******** *****

28. spacer 34.4|6320098|34|NC_010511|CRISPRCasFinder matches to NZ_CP016905 (Ralstonia solanacearum strain KACC 10709 plasmid unnamed1) position: , mismatch: 7, identity: 0.794

cggtcgggtccccgaacagatccgcctcgaccag	CRISPR spacer
cgcgctcgaccccgaacagctccgcctccaccag	Protospacer
**  *  * ********** ******** *****

29. spacer 34.4|6320098|34|NC_010511|CRISPRCasFinder matches to NZ_CP025986 (Ralstonia solanacearum strain RSCM plasmid p-unname2, complete sequence) position: , mismatch: 7, identity: 0.794

cggtcgggtccccgaacagatccgcctcgaccag	CRISPR spacer
cgcgctcgaccccgaacagctccgcctccaccag	Protospacer
**  *  * ********** ******** *****

30. spacer 34.4|6320098|34|NC_010511|CRISPRCasFinder matches to NZ_CP022769 (Ralstonia solanacearum strain T60 plasmid unnamed, complete sequence) position: , mismatch: 7, identity: 0.794

cggtcgggtccccgaacagatccgcctcgaccag	CRISPR spacer
cgcgctcgaccccgaacagctccgcctccaccag	Protospacer
**  *  * ********** ******** *****

31. spacer 34.4|6320098|34|NC_010511|CRISPRCasFinder matches to NZ_CP015851 (Ralstonia solanacearum strain YC40-M plasmid, complete sequence) position: , mismatch: 7, identity: 0.794

cggtcgggtccccgaacagatccgcctcgaccag	CRISPR spacer
cgcgctcgaccccgaacagctccgcctccaccag	Protospacer
**  *  * ********** ******** *****

32. spacer 34.4|6320098|34|NC_010511|CRISPRCasFinder matches to NZ_CP022773 (Ralstonia solanacearum strain T42 plasmid unnamed, complete sequence) position: , mismatch: 7, identity: 0.794

cggtcgggtccccgaacagatccgcctcgaccag	CRISPR spacer
cgcgctcgaccccgaacagctccgcctccaccag	Protospacer
**  *  * ********** ******** *****

33. spacer 34.4|6320098|34|NC_010511|CRISPRCasFinder matches to NZ_CP022783 (Ralstonia solanacearum strain SL3755 plasmid unnamed, complete sequence) position: , mismatch: 7, identity: 0.794

cggtcgggtccccgaacagatccgcctcgaccag	CRISPR spacer
cgcgctcgaccccgaacagctccgcctccaccag	Protospacer
**  *  * ********** ******** *****

34. spacer 34.4|6320098|34|NC_010511|CRISPRCasFinder matches to NZ_CP022791 (Ralstonia solanacearum strain SL3103 plasmid unnamed, complete sequence) position: , mismatch: 7, identity: 0.794

cggtcgggtccccgaacagatccgcctcgaccag	CRISPR spacer
cgcgctcgaccccgaacagctccgcctccaccag	Protospacer
**  *  * ********** ******** *****

35. spacer 34.4|6320098|34|NC_010511|CRISPRCasFinder matches to NZ_CP022795 (Ralstonia solanacearum strain SL2330 plasmid unnamed, complete sequence) position: , mismatch: 7, identity: 0.794

cggtcgggtccccgaacagatccgcctcgaccag	CRISPR spacer
cgcgctcgaccccgaacagctccgcctccaccag	Protospacer
**  *  * ********** ******** *****

36. spacer 34.4|6320098|34|NC_010511|CRISPRCasFinder matches to NZ_CP052071 (Ralstonia solanacearum strain FJAT454.F1 plasmid Plas1, complete sequence) position: , mismatch: 7, identity: 0.794

cggtcgggtccccgaacagatccgcctcgaccag	CRISPR spacer
cgcgctcgaccccgaacagctccgcctccaccag	Protospacer
**  *  * ********** ******** *****

37. spacer 34.4|6320098|34|NC_010511|CRISPRCasFinder matches to NZ_CP022482 (Ralstonia solanacearum strain HA4-1 plasmid HA4-1MP, complete sequence) position: , mismatch: 7, identity: 0.794

cggtcgggtccccgaacagatccgcctcgaccag	CRISPR spacer
cgcgctcgaccccgaacagctccgcctccaccag	Protospacer
**  *  * ********** ******** *****

38. spacer 34.4|6320098|34|NC_010511|CRISPRCasFinder matches to NZ_CP009763 (Ralstonia solanacearum OE1-1 plasmid unnamed, complete sequence) position: , mismatch: 7, identity: 0.794

cggtcgggtccccgaacagatccgcctcgaccag	CRISPR spacer
cgcgctcgaccccgaacagctccgcctccaccag	Protospacer
**  *  * ********** ******** *****

39. spacer 34.4|6320098|34|NC_010511|CRISPRCasFinder matches to CP023015 (Ralstonia solanacearum strain T25 plasmid unnamed, complete sequence) position: , mismatch: 7, identity: 0.794

cggtcgggtccccgaacagatccgcctcgaccag	CRISPR spacer
cgcgctcgaccccgaacagctccgcctccaccag	Protospacer
**  *  * ********** ******** *****

40. spacer 34.4|6320098|34|NC_010511|CRISPRCasFinder matches to NZ_CP022779 (Ralstonia solanacearum strain SL3882 plasmid unnamed, complete sequence) position: , mismatch: 7, identity: 0.794

cggtcgggtccccgaacagatccgcctcgaccag	CRISPR spacer
cgcgctcgaccccgaacagctccgcctccaccag	Protospacer
**  *  * ********** ******** *****

41. spacer 34.4|6320098|34|NC_010511|CRISPRCasFinder matches to NZ_CP052075 (Ralstonia solanacearum strain FJAT448.F1 plasmid Plas1, complete sequence) position: , mismatch: 7, identity: 0.794

cggtcgggtccccgaacagatccgcctcgaccag	CRISPR spacer
cgcgctcgaccccgaacagctccgcctccaccag	Protospacer
**  *  * ********** ******** *****

42. spacer 34.4|6320098|34|NC_010511|CRISPRCasFinder matches to NZ_CP052085 (Ralstonia solanacearum strain FJAT15353.F8 plasmid Plas1, complete sequence) position: , mismatch: 7, identity: 0.794

cggtcgggtccccgaacagatccgcctcgaccag	CRISPR spacer
cgcgctcgaccccgaacagctccgcctccaccag	Protospacer
**  *  * ********** ******** *****

43. spacer 34.4|6320098|34|NC_010511|CRISPRCasFinder matches to NZ_CP052095 (Ralstonia solanacearum strain FJAT15340.F1 plasmid Plas1, complete sequence) position: , mismatch: 7, identity: 0.794

cggtcgggtccccgaacagatccgcctcgaccag	CRISPR spacer
cgcgctcgaccccgaacagctccgcctccaccag	Protospacer
**  *  * ********** ******** *****

44. spacer 34.4|6320098|34|NC_010511|CRISPRCasFinder matches to NZ_CP052105 (Ralstonia solanacearum strain FJAT15252.F1 plasmid Plas1, complete sequence) position: , mismatch: 7, identity: 0.794

cggtcgggtccccgaacagatccgcctcgaccag	CRISPR spacer
cgcgctcgaccccgaacagctccgcctccaccag	Protospacer
**  *  * ********** ******** *****

45. spacer 34.4|6320098|34|NC_010511|CRISPRCasFinder matches to NZ_CP052077 (Ralstonia solanacearum strain FJAT445.F50 plasmid Plas1, complete sequence) position: , mismatch: 7, identity: 0.794

cggtcgggtccccgaacagatccgcctcgaccag	CRISPR spacer
cgcgctcgaccccgaacagctccgcctccaccag	Protospacer
**  *  * ********** ******** *****

46. spacer 34.4|6320098|34|NC_010511|CRISPRCasFinder matches to NZ_CP052087 (Ralstonia solanacearum strain FJAT15353.F50 plasmid Plas1, complete sequence) position: , mismatch: 7, identity: 0.794

cggtcgggtccccgaacagatccgcctcgaccag	CRISPR spacer
cgcgctcgaccccgaacagctccgcctccaccag	Protospacer
**  *  * ********** ******** *****

47. spacer 34.4|6320098|34|NC_010511|CRISPRCasFinder matches to NZ_CP052097 (Ralstonia solanacearum strain FJAT15304.F6 plasmid Plas1, complete sequence) position: , mismatch: 7, identity: 0.794

cggtcgggtccccgaacagatccgcctcgaccag	CRISPR spacer
cgcgctcgaccccgaacagctccgcctccaccag	Protospacer
**  *  * ********** ******** *****

48. spacer 34.4|6320098|34|NC_010511|CRISPRCasFinder matches to NZ_CP052115 (Ralstonia solanacearum strain FJAT1463.F50 plasmid Plas1, complete sequence) position: , mismatch: 7, identity: 0.794

cggtcgggtccccgaacagatccgcctcgaccag	CRISPR spacer
cgcgctcgaccccgaacagctccgcctccaccag	Protospacer
**  *  * ********** ******** *****

49. spacer 34.4|6320098|34|NC_010511|CRISPRCasFinder matches to NZ_CP052127 (Ralstonia solanacearum strain FJAT1303.F50 plasmid Plas1, complete sequence) position: , mismatch: 7, identity: 0.794

cggtcgggtccccgaacagatccgcctcgaccag	CRISPR spacer
cgcgctcgaccccgaacagctccgcctccaccag	Protospacer
**  *  * ********** ******** *****

50. spacer 34.4|6320098|34|NC_010511|CRISPRCasFinder matches to NZ_CP052079 (Ralstonia solanacearum strain FJAT445.F1 plasmid Plas1, complete sequence) position: , mismatch: 7, identity: 0.794

cggtcgggtccccgaacagatccgcctcgaccag	CRISPR spacer
cgcgctcgaccccgaacagctccgcctccaccag	Protospacer
**  *  * ********** ******** *****

51. spacer 34.4|6320098|34|NC_010511|CRISPRCasFinder matches to NZ_CP052089 (Ralstonia solanacearum strain FJAT15353.F1 plasmid Plas1, complete sequence) position: , mismatch: 7, identity: 0.794

cggtcgggtccccgaacagatccgcctcgaccag	CRISPR spacer
cgcgctcgaccccgaacagctccgcctccaccag	Protospacer
**  *  * ********** ******** *****

52. spacer 34.4|6320098|34|NC_010511|CRISPRCasFinder matches to NZ_CP052093 (Ralstonia solanacearum strain FJAT15340.F50 plasmid Plas1, complete sequence) position: , mismatch: 7, identity: 0.794

cggtcgggtccccgaacagatccgcctcgaccag	CRISPR spacer
cgcgctcgaccccgaacagctccgcctccaccag	Protospacer
**  *  * ********** ******** *****

53. spacer 34.4|6320098|34|NC_010511|CRISPRCasFinder matches to NZ_CP052101 (Ralstonia solanacearum strain FJAT15304.F1 plasmid Plas1, complete sequence) position: , mismatch: 7, identity: 0.794

cggtcgggtccccgaacagatccgcctcgaccag	CRISPR spacer
cgcgctcgaccccgaacagctccgcctccaccag	Protospacer
**  *  * ********** ******** *****

54. spacer 34.4|6320098|34|NC_010511|CRISPRCasFinder matches to NZ_CP052099 (Ralstonia solanacearum strain FJAT15304.F50 plasmid Plas1, complete sequence) position: , mismatch: 7, identity: 0.794

cggtcgggtccccgaacagatccgcctcgaccag	CRISPR spacer
cgcgctcgaccccgaacagctccgcctccaccag	Protospacer
**  *  * ********** ******** *****

55. spacer 34.4|6320098|34|NC_010511|CRISPRCasFinder matches to NZ_CP052107 (Ralstonia solanacearum strain FJAT15249.F50 plasmid Plas1, complete sequence) position: , mismatch: 7, identity: 0.794

cggtcgggtccccgaacagatccgcctcgaccag	CRISPR spacer
cgcgctcgaccccgaacagctccgcctccaccag	Protospacer
**  *  * ********** ******** *****

56. spacer 34.4|6320098|34|NC_010511|CRISPRCasFinder matches to NZ_CP022781 (Ralstonia solanacearum strain SL3822 plasmid unnamed, complete sequence) position: , mismatch: 7, identity: 0.794

cggtcgggtccccgaacagatccgcctcgaccag	CRISPR spacer
cgcgctcgaccccgaacagctccgcctccaccag	Protospacer
**  *  * ********** ******** *****

57. spacer 34.4|6320098|34|NC_010511|CRISPRCasFinder matches to NZ_CP052117 (Ralstonia solanacearum strain FJAT1463.F1 plasmid Plas1, complete sequence) position: , mismatch: 7, identity: 0.794

cggtcgggtccccgaacagatccgcctcgaccag	CRISPR spacer
cgcgctcgaccccgaacagctccgcctccaccag	Protospacer
**  *  * ********** ******** *****

58. spacer 34.4|6320098|34|NC_010511|CRISPRCasFinder matches to NZ_CP052125 (Ralstonia solanacearum strain FJAT1452.F1 plasmid Plas1, complete sequence) position: , mismatch: 7, identity: 0.794

cggtcgggtccccgaacagatccgcctcgaccag	CRISPR spacer
cgcgctcgaccccgaacagctccgcctccaccag	Protospacer
**  *  * ********** ******** *****

59. spacer 34.4|6320098|34|NC_010511|CRISPRCasFinder matches to NZ_CP022793 (Ralstonia solanacearum strain SL2729 plasmid unnamed, complete sequence) position: , mismatch: 7, identity: 0.794

cggtcgggtccccgaacagatccgcctcgaccag	CRISPR spacer
cgcgctcgaccccgaacagctccgcctccaccag	Protospacer
**  *  * ********** ******** *****

60. spacer 34.4|6320098|34|NC_010511|CRISPRCasFinder matches to NZ_CP022785 (Ralstonia solanacearum strain SL3730 plasmid unnamed, complete sequence) position: , mismatch: 7, identity: 0.794

cggtcgggtccccgaacagatccgcctcgaccag	CRISPR spacer
cgcgctcgaccccgaacagctccgcctccaccag	Protospacer
**  *  * ********** ******** *****

61. spacer 34.4|6320098|34|NC_010511|CRISPRCasFinder matches to NZ_CP022787 (Ralstonia solanacearum strain SL3300 plasmid unnamed, complete sequence) position: , mismatch: 7, identity: 0.794

cggtcgggtccccgaacagatccgcctcgaccag	CRISPR spacer
cgcgctcgaccccgaacagctccgcctccaccag	Protospacer
**  *  * ********** ******** *****

62. spacer 34.4|6320098|34|NC_010511|CRISPRCasFinder matches to NZ_CP022756 (Ralstonia solanacearum strain T117 plasmid unnamed, complete sequence) position: , mismatch: 7, identity: 0.794

cggtcgggtccccgaacagatccgcctcgaccag	CRISPR spacer
cgcgctcgaccccgaacagctccgcctccaccag	Protospacer
**  *  * ********** ******** *****

63. spacer 34.4|6320098|34|NC_010511|CRISPRCasFinder matches to NZ_CP052129 (Ralstonia solanacearum strain FJAT1303.F1 plasmid Plas1, complete sequence) position: , mismatch: 7, identity: 0.794

cggtcgggtccccgaacagatccgcctcgaccag	CRISPR spacer
cgcgctcgaccccgaacagctccgcctccaccag	Protospacer
**  *  * ********** ******** *****

64. spacer 34.4|6320098|34|NC_010511|CRISPRCasFinder matches to NZ_CP052121 (Ralstonia solanacearum strain FJAT1458.F1 plasmid Plas1, complete sequence) position: , mismatch: 7, identity: 0.794

cggtcgggtccccgaacagatccgcctcgaccag	CRISPR spacer
cgcgctcgaccccgaacagctccgcctccaccag	Protospacer
**  *  * ********** ******** *****

65. spacer 34.4|6320098|34|NC_010511|CRISPRCasFinder matches to NZ_CP052123 (Ralstonia solanacearum strain FJAT1452.F50 plasmid Plas1, complete sequence) position: , mismatch: 7, identity: 0.794

cggtcgggtccccgaacagatccgcctcgaccag	CRISPR spacer
cgcgctcgaccccgaacagctccgcctccaccag	Protospacer
**  *  * ********** ******** *****

66. spacer 34.4|6320098|34|NC_010511|CRISPRCasFinder matches to NZ_CP052131 (Ralstonia solanacearum strain FJAT1303.F8 plasmid Plas1, complete sequence) position: , mismatch: 7, identity: 0.794

cggtcgggtccccgaacagatccgcctcgaccag	CRISPR spacer
cgcgctcgaccccgaacagctccgcctccaccag	Protospacer
**  *  * ********** ******** *****

67. spacer 34.4|6320098|34|NC_010511|CRISPRCasFinder matches to CP011998 (Ralstonia solanacearum strain YC45 plasmid, complete sequence) position: , mismatch: 7, identity: 0.794

cggtcgggtccccgaacagatccgcctcgaccag	CRISPR spacer
cgcgctcgaccccgaacagctccgcctccaccag	Protospacer
**  *  * ********** ******** *****

68. spacer 34.4|6320098|34|NC_010511|CRISPRCasFinder matches to NZ_CP052073 (Ralstonia solanacearum strain FJAT448.F50 plasmid Plas1, complete sequence) position: , mismatch: 7, identity: 0.794

cggtcgggtccccgaacagatccgcctcgaccag	CRISPR spacer
cgcgctcgaccccgaacagctccgcctccaccag	Protospacer
**  *  * ********** ******** *****

69. spacer 34.4|6320098|34|NC_010511|CRISPRCasFinder matches to NZ_CP052081 (Ralstonia solanacearum strain FJAT442.F50 plasmid Plas1, complete sequence) position: , mismatch: 7, identity: 0.794

cggtcgggtccccgaacagatccgcctcgaccag	CRISPR spacer
cgcgctcgaccccgaacagctccgcctccaccag	Protospacer
**  *  * ********** ******** *****

70. spacer 34.4|6320098|34|NC_010511|CRISPRCasFinder matches to NZ_CP052083 (Ralstonia solanacearum strain FJAT442.F1 plasmid Plas1, complete sequence) position: , mismatch: 7, identity: 0.794

cggtcgggtccccgaacagatccgcctcgaccag	CRISPR spacer
cgcgctcgaccccgaacagctccgcctccaccag	Protospacer
**  *  * ********** ******** *****

71. spacer 34.4|6320098|34|NC_010511|CRISPRCasFinder matches to NZ_CP052109 (Ralstonia solanacearum strain FJAT15249.F1 plasmid Plas1, complete sequence) position: , mismatch: 7, identity: 0.794

cggtcgggtccccgaacagatccgcctcgaccag	CRISPR spacer
cgcgctcgaccccgaacagctccgcctccaccag	Protospacer
**  *  * ********** ******** *****

72. spacer 34.4|6320098|34|NC_010511|CRISPRCasFinder matches to NZ_CP052091 (Ralstonia solanacearum strain FJAT15340.F6 plasmid Plas1, complete sequence) position: , mismatch: 7, identity: 0.794

cggtcgggtccccgaacagatccgcctcgaccag	CRISPR spacer
cgcgctcgaccccgaacagctccgcctccaccag	Protospacer
**  *  * ********** ******** *****

73. spacer 34.4|6320098|34|NC_010511|CRISPRCasFinder matches to NZ_CP052111 (Ralstonia solanacearum strain FJAT15244.F50 plasmid Plas1, complete sequence) position: , mismatch: 7, identity: 0.794

cggtcgggtccccgaacagatccgcctcgaccag	CRISPR spacer
cgcgctcgaccccgaacagctccgcctccaccag	Protospacer
**  *  * ********** ******** *****

74. spacer 34.4|6320098|34|NC_010511|CRISPRCasFinder matches to NZ_CP052103 (Ralstonia solanacearum strain FJAT15252.F50 plasmid Plas1, complete sequence) position: , mismatch: 7, identity: 0.794

cggtcgggtccccgaacagatccgcctcgaccag	CRISPR spacer
cgcgctcgaccccgaacagctccgcctccaccag	Protospacer
**  *  * ********** ******** *****

75. spacer 34.4|6320098|34|NC_010511|CRISPRCasFinder matches to NZ_CP052119 (Ralstonia solanacearum strain FJAT1458.F50 plasmid Plas1, complete sequence) position: , mismatch: 7, identity: 0.794

cggtcgggtccccgaacagatccgcctcgaccag	CRISPR spacer
cgcgctcgaccccgaacagctccgcctccaccag	Protospacer
**  *  * ********** ******** *****

76. spacer 34.4|6320098|34|NC_010511|CRISPRCasFinder matches to NZ_CP052113 (Ralstonia solanacearum strain FJAT15244.F1 plasmid Plas1, complete sequence) position: , mismatch: 7, identity: 0.794

cggtcgggtccccgaacagatccgcctcgaccag	CRISPR spacer
cgcgctcgaccccgaacagctccgcctccaccag	Protospacer
**  *  * ********** ******** *****

77. spacer 36.1|6830766|29|NC_010511|CRISPRCasFinder matches to NZ_CP032349 (Azospirillum brasilense strain MTCC4039 plasmid p3, complete sequence) position: , mismatch: 7, identity: 0.759

gaagccatcaaccggatgtcggatgacac	CRISPR spacer
caggccatcaaccggctgtccgatgaaca	Protospacer
 *.************ **** *****

78. spacer 6.1|725596|32|NC_010511|CRISPRCasFinder matches to NZ_CP021821 (Sinorhizobium meliloti strain M162 plasmid accessoryA, complete sequence) position: , mismatch: 8, identity: 0.75

gatgaagacgaccggcagcgtca----agggcacct	CRISPR spacer
gatgacgacgaccggcagcttcatccggcggc----	Protospacer
***** ************* ***    . ***

79. spacer 6.1|725596|32|NC_010511|CRISPRCasFinder matches to NZ_CP021813 (Sinorhizobium meliloti strain M270 plasmid psymA, complete sequence) position: , mismatch: 8, identity: 0.75

gatgaagacgaccggcagcgtca----agggcacct	CRISPR spacer
gatgacgacgaccggcagcttcatccggcggc----	Protospacer
***** ************* ***    . ***

80. spacer 11.4|1944015|35|NC_010511|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP030828 (Neorhizobium sp. NCHU2750 plasmid pNCHU2750a, complete sequence) position: , mismatch: 8, identity: 0.771

--aaggcgaccgtgcccgcgatcatcgaggtgcggtg	CRISPR spacer
tttcggcg--cgtgcccgtgatcatcgaggcgcggcc	Protospacer
    ****  ********.***********.****.

81. spacer 14.3|2625295|33|NC_010511|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP022666 (Rhizobium leguminosarum bv. viciae strain BIHB 1217 plasmid pPR1, complete sequence) position: , mismatch: 8, identity: 0.758

ttgctgcggccttgatcgtcattcgatcctggc--	CRISPR spacer
gcgctgcggccatgatcgtcactcgagc--gaccg	Protospacer
 .********* *********.**** *  *.*

82. spacer 14.3|2625295|33|NC_010511|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP050086 (Rhizobium leguminosarum bv. trifolii strain 23B plasmid pRL23b7, complete sequence) position: , mismatch: 8, identity: 0.758

ttgctgcggccttgatcgtcattcgatcctggc--	CRISPR spacer
gcgctgcggccatgatcgtcactcgagc--gaccg	Protospacer
 .********* *********.**** *  *.*

83. spacer 17.1|3091259|31|NC_010511|CRISPRCasFinder matches to NZ_CP010408 (Streptomyces vietnamensis strain GIMV4.0001 plasmid pSVL1, complete sequence) position: , mismatch: 8, identity: 0.742

tgcgaagcaatccgtcggatgtcgtatccca	CRISPR spacer
agcgaatcaatccgccggatgtcgacctcga	Protospacer
 ***** *******.*********  ..* *

84. spacer 24.1|4168034|33|NC_010511|CRISPRCasFinder matches to NZ_CP032319 (Hymenobacter oligotrophus strain sh-6 plasmid unnamed2, complete sequence) position: , mismatch: 8, identity: 0.758

acgtatgacaagcccgcgcggcgcctgagcgaa	CRISPR spacer
acgtaggacaagcccgagcggcgcaggaaatag	Protospacer
***** ********** *******  **.  *.

85. spacer 34.1|6319896|34|NC_010511|CRISPRCasFinder matches to NZ_CP016452 (Sinorhizobium sp. RAC02 plasmid pBSY16_1, complete sequence) position: , mismatch: 8, identity: 0.765

cggcgccggccttgccgtcctttagcgcctgaca	CRISPR spacer
cggtcacggccttgccgtccttcatcgccttagc	Protospacer
***.  ****************.* ***** *

86. spacer 34.4|6320098|34|NC_010511|CRISPRCasFinder matches to NZ_CP032685 (Rhizobium sp. CCGE531 plasmid pRCCGE531d, complete sequence) position: , mismatch: 8, identity: 0.765

cggtcgggtccccgaacagatccgcctcgaccag	CRISPR spacer
cggaatccgccccgaacatatccgcatcgaccag	Protospacer
***      ********* ****** ********

87. spacer 34.4|6320098|34|NC_010511|CRISPRCasFinder matches to NZ_CP032690 (Rhizobium sp. CCGE532 plasmid pRCCGE532d, complete sequence) position: , mismatch: 8, identity: 0.765

cggtcgggtccccgaacagatccgcctcgaccag	CRISPR spacer
cggaatccgccccgaacatatccgcatcgaccag	Protospacer
***      ********* ****** ********

88. spacer 34.5|6320165|33|NC_010511|CRISPRCasFinder matches to NZ_AP022593 (Mycolicibacterium arabiense strain JCM 18538 plasmid pJCM18538, complete sequence) position: , mismatch: 8, identity: 0.758

gggatggcccctcggccagcacgcgtcgcagga	CRISPR spacer
ggaagccgacctcggccagcaggcgtcgcacga	Protospacer
**.*     ************ ******** **

89. spacer 34.7|6320299|34|NC_010511|CRISPRCasFinder matches to NC_004574 (Ruegeria sp. PR1b plasmid pSD25, complete sequence) position: , mismatch: 8, identity: 0.765

aggacggccagggcggcgcgctgctcttcctcaa	CRISPR spacer
caggcggccacggcggcgcgctgcgcttccgtga	Protospacer
 .*.****** ************* ***** ..*

90. spacer 34.7|6320299|34|NC_010511|CRISPRCasFinder matches to NZ_CP030864 (Streptomyces globosus strain LZH-48 plasmid unnamed2, complete sequence) position: , mismatch: 8, identity: 0.765

aggacggccagggcggcgcgctgctcttcctcaa	CRISPR spacer
tggagggccagggcggcgcgccgctctgctgccg	Protospacer
 *** ****************.***** *. * .

91. spacer 34.7|6320299|34|NC_010511|CRISPRCasFinder matches to NZ_CP016613 (Ralstonia solanacearum FJAT-91 plasmid unnamed1, complete sequence) position: , mismatch: 8, identity: 0.765

aggacggccagggcggcgcgctgctcttcctcaa	CRISPR spacer
aggacggccagcgcggcgtgctgctgtcgatcct	Protospacer
*********** ******.****** *.  **

92. spacer 34.7|6320299|34|NC_010511|CRISPRCasFinder matches to NZ_CP021449 (Ralstonia solanacearum strain SEPPX05 plasmid pSEPPX05, complete sequence) position: , mismatch: 8, identity: 0.765

aggacggccagggcggcgcgctgctcttcctcaa	CRISPR spacer
aggacggccagcgcggcgtgctgctgtcgatcct	Protospacer
*********** ******.****** *.  **

93. spacer 34.7|6320299|34|NC_010511|CRISPRCasFinder matches to NZ_CP026091 (Ralstonia solanacearum strain IBSBF 2570 plasmid unnamed, complete sequence) position: , mismatch: 8, identity: 0.765

aggacggccagggcggcgcgctgctcttcctcaa	CRISPR spacer
aggacggccagcgcggcgtgctgctgtcgatcct	Protospacer
*********** ******.****** *.  **

94. spacer 34.7|6320299|34|NC_010511|CRISPRCasFinder matches to NC_014309 (Ralstonia solanacearum CFBP2957 plasmid RCFBPv3_mp, complete genome) position: , mismatch: 8, identity: 0.765

aggacggccagggcggcgcgctgctcttcctcaa	CRISPR spacer
aggacggccagcgcggcgtgctgctgtcgatcct	Protospacer
*********** ******.****** *.  **

95. spacer 34.7|6320299|34|NC_010511|CRISPRCasFinder matches to CP023013 (Ralstonia solanacearum strain T110 plasmid unnamed, complete sequence) position: , mismatch: 8, identity: 0.765

aggacggccagggcggcgcgctgctcttcctcaa	CRISPR spacer
aggacggccagcgcggcgtgctgctgtcgatcct	Protospacer
*********** ******.****** *.  **

96. spacer 34.7|6320299|34|NC_010511|CRISPRCasFinder matches to NZ_CP021653 (Ralstonia solanacearum strain RS 488 plasmid unnamed, complete sequence) position: , mismatch: 8, identity: 0.765

aggacggccagggcggcgcgctgctcttcctcaa	CRISPR spacer
aggacggccagcgcggcgtgctgctgtcgatcct	Protospacer
*********** ******.****** *.  **

97. spacer 34.7|6320299|34|NC_010511|CRISPRCasFinder matches to NZ_CP049790 (Ralstonia solanacearum strain 202 plasmid unnamed, complete sequence) position: , mismatch: 8, identity: 0.765

aggacggccagggcggcgcgctgctcttcctcaa	CRISPR spacer
aggacggccagcgcggcgtgctgctgtcgatcct	Protospacer
*********** ******.****** *.  **

98. spacer 34.7|6320299|34|NC_010511|CRISPRCasFinder matches to NZ_CP049794 (Ralstonia solanacearum strain 204 plasmid unnamed, complete sequence) position: , mismatch: 8, identity: 0.765

aggacggccagggcggcgcgctgctcttcctcaa	CRISPR spacer
aggacggccagcgcggcgtgctgctgtcgatcct	Protospacer
*********** ******.****** *.  **

99. spacer 34.7|6320299|34|NC_010511|CRISPRCasFinder matches to NZ_CP049788 (Ralstonia solanacearum strain B2 plasmid unnamed, complete sequence) position: , mismatch: 8, identity: 0.765

aggacggccagggcggcgcgctgctcttcctcaa	CRISPR spacer
aggacggccagcgcggcgtgctgctgtcgatcct	Protospacer
*********** ******.****** *.  **

100. spacer 34.7|6320299|34|NC_010511|CRISPRCasFinder matches to NZ_CP022766 (Ralstonia solanacearum strain T78 plasmid unnamed, complete sequence) position: , mismatch: 8, identity: 0.765

aggacggccagggcggcgcgctgctcttcctcaa	CRISPR spacer
aggacggccagcgcggcgtgctgctgtcgatcct	Protospacer
*********** ******.****** *.  **

101. spacer 34.7|6320299|34|NC_010511|CRISPRCasFinder matches to NZ_CP039340 (Ralstonia solanacearum strain UW386 plasmid pUW386, complete sequence) position: , mismatch: 8, identity: 0.765

aggacggccagggcggcgcgctgctcttcctcaa	CRISPR spacer
aggacggccagcgcggcgtgctgctgtcgatcct	Protospacer
*********** ******.****** *.  **

102. spacer 34.7|6320299|34|NC_010511|CRISPRCasFinder matches to NZ_CP021763 (Ralstonia pseudosolanacearum strain RS 476 plasmid unnamed, complete sequence) position: , mismatch: 8, identity: 0.765

aggacggccagggcggcgcgctgctcttcctcaa	CRISPR spacer
aggacggccagcgcggcgtgctgctgtcgatcct	Protospacer
*********** ******.****** *.  **

103. spacer 34.7|6320299|34|NC_010511|CRISPRCasFinder matches to NZ_CP026093 (Ralstonia solanacearum strain SFC plasmid unnamed, complete sequence) position: , mismatch: 8, identity: 0.765

aggacggccagggcggcgcgctgctcttcctcaa	CRISPR spacer
aggacggccagcgcggcgtgctgctgtcgatcct	Protospacer
*********** ******.****** *.  **

104. spacer 34.7|6320299|34|NC_010511|CRISPRCasFinder matches to NZ_CP021767 (Ralstonia solanacearum strain RS 489 plasmid unnamed, complete sequence) position: , mismatch: 8, identity: 0.765

aggacggccagggcggcgcgctgctcttcctcaa	CRISPR spacer
aggacggccagcgcggcgtgctgctgtcgatcct	Protospacer
*********** ******.****** *.  **

105. spacer 34.7|6320299|34|NC_010511|CRISPRCasFinder matches to NZ_CP015116 (Ralstonia solanacearum strain EP1 plasmid unnamed, complete sequence) position: , mismatch: 8, identity: 0.765

aggacggccagggcggcgcgctgctcttcctcaa	CRISPR spacer
aggacggccagcgcggcgtgctgctgtcgatcct	Protospacer
*********** ******.****** *.  **

106. spacer 34.7|6320299|34|NC_010511|CRISPRCasFinder matches to NZ_CP016555 (Ralstonia solanacearum FJAT-1458 plasmid plas1, complete sequence) position: , mismatch: 8, identity: 0.765

aggacggccagggcggcgcgctgctcttcctcaa	CRISPR spacer
aggacggccagcgcggcgtgctgctgtcgatcct	Protospacer
*********** ******.****** *.  **

107. spacer 34.7|6320299|34|NC_010511|CRISPRCasFinder matches to NZ_CP012940 (Ralstonia solanacearum strain UW163 plasmid unnamed, complete sequence) position: , mismatch: 8, identity: 0.765

aggacggccagggcggcgcgctgctcttcctcaa	CRISPR spacer
aggacggccagcgcggcgtgctgctgtcgatcct	Protospacer
*********** ******.****** *.  **

108. spacer 34.7|6320299|34|NC_010511|CRISPRCasFinder matches to NZ_CP012944 (Ralstonia solanacearum strain IBSBF1503 plasmid unnamed, complete sequence) position: , mismatch: 8, identity: 0.765

aggacggccagggcggcgcgctgctcttcctcaa	CRISPR spacer
aggacggccagcgcggcgtgctgctgtcgatcct	Protospacer
*********** ******.****** *.  **

109. spacer 34.7|6320299|34|NC_010511|CRISPRCasFinder matches to NZ_CP012688 (Ralstonia solanacearum strain UY031 plasmid unnamed, complete sequence) position: , mismatch: 8, identity: 0.765

aggacggccagggcggcgcgctgctcttcctcaa	CRISPR spacer
aggacggccagcgcggcgtgctgctgtcgatcct	Protospacer
*********** ******.****** *.  **

110. spacer 34.7|6320299|34|NC_010511|CRISPRCasFinder matches to NZ_CP049792 (Ralstonia solanacearum strain 203 plasmid unnamed, complete sequence) position: , mismatch: 8, identity: 0.765

aggacggccagggcggcgcgctgctcttcctcaa	CRISPR spacer
aggacggccagcgcggcgtgctgctgtcgatcct	Protospacer
*********** ******.****** *.  **

111. spacer 34.7|6320299|34|NC_010511|CRISPRCasFinder matches to NZ_CP052069 (Ralstonia solanacearum strain FJAT91.F50 plasmid Plas1, complete sequence) position: , mismatch: 8, identity: 0.765

aggacggccagggcggcgcgctgctcttcctcaa	CRISPR spacer
aggacggccagcgcggcgtgctgctgtcgatcct	Protospacer
*********** ******.****** *.  **

112. spacer 34.7|6320299|34|NC_010511|CRISPRCasFinder matches to NZ_CP016915 (Ralstonia solanacearum strain CQPS-1 plasmid unnamed, complete sequence) position: , mismatch: 8, identity: 0.765

aggacggccagggcggcgcgctgctcttcctcaa	CRISPR spacer
aggacggccagcgcggcgtgctgctgtcgatcct	Protospacer
*********** ******.****** *.  **

113. spacer 34.7|6320299|34|NC_010511|CRISPRCasFinder matches to NZ_CP016905 (Ralstonia solanacearum strain KACC 10709 plasmid unnamed1) position: , mismatch: 8, identity: 0.765

aggacggccagggcggcgcgctgctcttcctcaa	CRISPR spacer
aggacggccagcgcggcgtgctgctgtcgatcct	Protospacer
*********** ******.****** *.  **

114. spacer 34.7|6320299|34|NC_010511|CRISPRCasFinder matches to NZ_CP025986 (Ralstonia solanacearum strain RSCM plasmid p-unname2, complete sequence) position: , mismatch: 8, identity: 0.765

aggacggccagggcggcgcgctgctcttcctcaa	CRISPR spacer
aggacggccagcgcggcgtgctgctgtcgatcct	Protospacer
*********** ******.****** *.  **

115. spacer 34.7|6320299|34|NC_010511|CRISPRCasFinder matches to NZ_CP022769 (Ralstonia solanacearum strain T60 plasmid unnamed, complete sequence) position: , mismatch: 8, identity: 0.765

aggacggccagggcggcgcgctgctcttcctcaa	CRISPR spacer
aggacggccagcgcggcgtgctgctgtcgatcct	Protospacer
*********** ******.****** *.  **

116. spacer 34.7|6320299|34|NC_010511|CRISPRCasFinder matches to NZ_CP015851 (Ralstonia solanacearum strain YC40-M plasmid, complete sequence) position: , mismatch: 8, identity: 0.765

aggacggccagggcggcgcgctgctcttcctcaa	CRISPR spacer
aggacggccagcgcggcgtgctgctgtcgatcct	Protospacer
*********** ******.****** *.  **

117. spacer 34.7|6320299|34|NC_010511|CRISPRCasFinder matches to NZ_CP022773 (Ralstonia solanacearum strain T42 plasmid unnamed, complete sequence) position: , mismatch: 8, identity: 0.765

aggacggccagggcggcgcgctgctcttcctcaa	CRISPR spacer
aggacggccagcgcggcgtgctgctgtcgatcct	Protospacer
*********** ******.****** *.  **

118. spacer 34.7|6320299|34|NC_010511|CRISPRCasFinder matches to NZ_CP022783 (Ralstonia solanacearum strain SL3755 plasmid unnamed, complete sequence) position: , mismatch: 8, identity: 0.765

aggacggccagggcggcgcgctgctcttcctcaa	CRISPR spacer
aggacggccagcgcggcgtgctgctgtcgatcct	Protospacer
*********** ******.****** *.  **

119. spacer 34.7|6320299|34|NC_010511|CRISPRCasFinder matches to NZ_CP022791 (Ralstonia solanacearum strain SL3103 plasmid unnamed, complete sequence) position: , mismatch: 8, identity: 0.765

aggacggccagggcggcgcgctgctcttcctcaa	CRISPR spacer
aggacggccagcgcggcgtgctgctgtcgatcct	Protospacer
*********** ******.****** *.  **

120. spacer 34.7|6320299|34|NC_010511|CRISPRCasFinder matches to NZ_CP022795 (Ralstonia solanacearum strain SL2330 plasmid unnamed, complete sequence) position: , mismatch: 8, identity: 0.765

aggacggccagggcggcgcgctgctcttcctcaa	CRISPR spacer
aggacggccagcgcggcgtgctgctgtcgatcct	Protospacer
*********** ******.****** *.  **

121. spacer 34.7|6320299|34|NC_010511|CRISPRCasFinder matches to NZ_CP052071 (Ralstonia solanacearum strain FJAT454.F1 plasmid Plas1, complete sequence) position: , mismatch: 8, identity: 0.765

aggacggccagggcggcgcgctgctcttcctcaa	CRISPR spacer
aggacggccagcgcggcgtgctgctgtcgatcct	Protospacer
*********** ******.****** *.  **

122. spacer 34.7|6320299|34|NC_010511|CRISPRCasFinder matches to NC_017575 (Ralstonia solanacearum Po82 megaplasmid, complete sequence) position: , mismatch: 8, identity: 0.765

aggacggccagggcggcgcgctgctcttcctcaa	CRISPR spacer
aggacggccagcgcggcgtgctgctgtcgatcct	Protospacer
*********** ******.****** *.  **

123. spacer 34.7|6320299|34|NC_010511|CRISPRCasFinder matches to NZ_CP022482 (Ralstonia solanacearum strain HA4-1 plasmid HA4-1MP, complete sequence) position: , mismatch: 8, identity: 0.765

aggacggccagggcggcgcgctgctcttcctcaa	CRISPR spacer
aggacggccagcgcggcgtgctgctgtcgatcct	Protospacer
*********** ******.****** *.  **

124. spacer 34.7|6320299|34|NC_010511|CRISPRCasFinder matches to NZ_CP009763 (Ralstonia solanacearum OE1-1 plasmid unnamed, complete sequence) position: , mismatch: 8, identity: 0.765

aggacggccagggcggcgcgctgctcttcctcaa	CRISPR spacer
aggacggccagcgcggcgtgctgctgtcgatcct	Protospacer
*********** ******.****** *.  **

125. spacer 34.7|6320299|34|NC_010511|CRISPRCasFinder matches to CP023015 (Ralstonia solanacearum strain T25 plasmid unnamed, complete sequence) position: , mismatch: 8, identity: 0.765

aggacggccagggcggcgcgctgctcttcctcaa	CRISPR spacer
aggacggccagcgcggcgtgctgctgtcgatcct	Protospacer
*********** ******.****** *.  **

126. spacer 34.7|6320299|34|NC_010511|CRISPRCasFinder matches to NZ_CP022779 (Ralstonia solanacearum strain SL3882 plasmid unnamed, complete sequence) position: , mismatch: 8, identity: 0.765

aggacggccagggcggcgcgctgctcttcctcaa	CRISPR spacer
aggacggccagcgcggcgtgctgctgtcgatcct	Protospacer
*********** ******.****** *.  **

127. spacer 34.7|6320299|34|NC_010511|CRISPRCasFinder matches to NZ_CP052075 (Ralstonia solanacearum strain FJAT448.F1 plasmid Plas1, complete sequence) position: , mismatch: 8, identity: 0.765

aggacggccagggcggcgcgctgctcttcctcaa	CRISPR spacer
aggacggccagcgcggcgtgctgctgtcgatcct	Protospacer
*********** ******.****** *.  **

128. spacer 34.7|6320299|34|NC_010511|CRISPRCasFinder matches to NZ_CP052085 (Ralstonia solanacearum strain FJAT15353.F8 plasmid Plas1, complete sequence) position: , mismatch: 8, identity: 0.765

aggacggccagggcggcgcgctgctcttcctcaa	CRISPR spacer
aggacggccagcgcggcgtgctgctgtcgatcct	Protospacer
*********** ******.****** *.  **

129. spacer 34.7|6320299|34|NC_010511|CRISPRCasFinder matches to NZ_CP052095 (Ralstonia solanacearum strain FJAT15340.F1 plasmid Plas1, complete sequence) position: , mismatch: 8, identity: 0.765

aggacggccagggcggcgcgctgctcttcctcaa	CRISPR spacer
aggacggccagcgcggcgtgctgctgtcgatcct	Protospacer
*********** ******.****** *.  **

130. spacer 34.7|6320299|34|NC_010511|CRISPRCasFinder matches to NZ_CP052105 (Ralstonia solanacearum strain FJAT15252.F1 plasmid Plas1, complete sequence) position: , mismatch: 8, identity: 0.765

aggacggccagggcggcgcgctgctcttcctcaa	CRISPR spacer
aggacggccagcgcggcgtgctgctgtcgatcct	Protospacer
*********** ******.****** *.  **

131. spacer 34.7|6320299|34|NC_010511|CRISPRCasFinder matches to NZ_CP026308 (Ralstonia solanacearum strain IBSBF 2571 plasmid unnamed, complete sequence) position: , mismatch: 8, identity: 0.765

aggacggccagggcggcgcgctgctcttcctcaa	CRISPR spacer
aggacggccagcgcggcgtgctgctgtcgatcct	Protospacer
*********** ******.****** *.  **

132. spacer 34.7|6320299|34|NC_010511|CRISPRCasFinder matches to NZ_CP021765 (Ralstonia pseudosolanacearum strain CRMRs218 plasmid unnamed, complete sequence) position: , mismatch: 8, identity: 0.765

aggacggccagggcggcgcgctgctcttcctcaa	CRISPR spacer
aggacggccagcgcggcgtgctgctgtcgatcct	Protospacer
*********** ******.****** *.  **

133. spacer 34.7|6320299|34|NC_010511|CRISPRCasFinder matches to NZ_CP052077 (Ralstonia solanacearum strain FJAT445.F50 plasmid Plas1, complete sequence) position: , mismatch: 8, identity: 0.765

aggacggccagggcggcgcgctgctcttcctcaa	CRISPR spacer
aggacggccagcgcggcgtgctgctgtcgatcct	Protospacer
*********** ******.****** *.  **

134. spacer 34.7|6320299|34|NC_010511|CRISPRCasFinder matches to NZ_CP052087 (Ralstonia solanacearum strain FJAT15353.F50 plasmid Plas1, complete sequence) position: , mismatch: 8, identity: 0.765

aggacggccagggcggcgcgctgctcttcctcaa	CRISPR spacer
aggacggccagcgcggcgtgctgctgtcgatcct	Protospacer
*********** ******.****** *.  **

135. spacer 34.7|6320299|34|NC_010511|CRISPRCasFinder matches to NZ_CP052097 (Ralstonia solanacearum strain FJAT15304.F6 plasmid Plas1, complete sequence) position: , mismatch: 8, identity: 0.765

aggacggccagggcggcgcgctgctcttcctcaa	CRISPR spacer
aggacggccagcgcggcgtgctgctgtcgatcct	Protospacer
*********** ******.****** *.  **

136. spacer 34.7|6320299|34|NC_010511|CRISPRCasFinder matches to CP047139 (Ralstonia solanacearum strain CFBP 8695 plasmid unnamed, complete sequence) position: , mismatch: 8, identity: 0.765

aggacggccagggcggcgcgctgctcttcctcaa	CRISPR spacer
aggacggccagcgcggcgtgctgctgtcgatcct	Protospacer
*********** ******.****** *.  **

137. spacer 34.7|6320299|34|NC_010511|CRISPRCasFinder matches to NZ_CP051295 (Ralstonia solanacearum strain CIAT_078 plasmid megaplasmid, complete sequence) position: , mismatch: 8, identity: 0.765

aggacggccagggcggcgcgctgctcttcctcaa	CRISPR spacer
aggacggccagcgcggcgtgctgctgtcgatcct	Protospacer
*********** ******.****** *.  **

138. spacer 34.7|6320299|34|NC_010511|CRISPRCasFinder matches to NZ_CP052115 (Ralstonia solanacearum strain FJAT1463.F50 plasmid Plas1, complete sequence) position: , mismatch: 8, identity: 0.765

aggacggccagggcggcgcgctgctcttcctcaa	CRISPR spacer
aggacggccagcgcggcgtgctgctgtcgatcct	Protospacer
*********** ******.****** *.  **

139. spacer 34.7|6320299|34|NC_010511|CRISPRCasFinder matches to NZ_CP052127 (Ralstonia solanacearum strain FJAT1303.F50 plasmid Plas1, complete sequence) position: , mismatch: 8, identity: 0.765

aggacggccagggcggcgcgctgctcttcctcaa	CRISPR spacer
aggacggccagcgcggcgtgctgctgtcgatcct	Protospacer
*********** ******.****** *.  **

140. spacer 34.7|6320299|34|NC_010511|CRISPRCasFinder matches to CP047137 (Ralstonia solanacearum strain CFBP 8697 plasmid unnamed, complete sequence) position: , mismatch: 8, identity: 0.765

aggacggccagggcggcgcgctgctcttcctcaa	CRISPR spacer
aggacggccagcgcggcgtgctgctatcgatcct	Protospacer
*********** ******.****** *.  **

141. spacer 34.7|6320299|34|NC_010511|CRISPRCasFinder matches to NZ_CP052079 (Ralstonia solanacearum strain FJAT445.F1 plasmid Plas1, complete sequence) position: , mismatch: 8, identity: 0.765

aggacggccagggcggcgcgctgctcttcctcaa	CRISPR spacer
aggacggccagcgcggcgtgctgctgtcgatcct	Protospacer
*********** ******.****** *.  **

142. spacer 34.7|6320299|34|NC_010511|CRISPRCasFinder matches to NZ_CP052089 (Ralstonia solanacearum strain FJAT15353.F1 plasmid Plas1, complete sequence) position: , mismatch: 8, identity: 0.765

aggacggccagggcggcgcgctgctcttcctcaa	CRISPR spacer
aggacggccagcgcggcgtgctgctgtcgatcct	Protospacer
*********** ******.****** *.  **

143. spacer 34.7|6320299|34|NC_010511|CRISPRCasFinder matches to NZ_CP052093 (Ralstonia solanacearum strain FJAT15340.F50 plasmid Plas1, complete sequence) position: , mismatch: 8, identity: 0.765

aggacggccagggcggcgcgctgctcttcctcaa	CRISPR spacer
aggacggccagcgcggcgtgctgctgtcgatcct	Protospacer
*********** ******.****** *.  **

144. spacer 34.7|6320299|34|NC_010511|CRISPRCasFinder matches to NZ_CP052101 (Ralstonia solanacearum strain FJAT15304.F1 plasmid Plas1, complete sequence) position: , mismatch: 8, identity: 0.765

aggacggccagggcggcgcgctgctcttcctcaa	CRISPR spacer
aggacggccagcgcggcgtgctgctgtcgatcct	Protospacer
*********** ******.****** *.  **

145. spacer 34.7|6320299|34|NC_010511|CRISPRCasFinder matches to NZ_CP052099 (Ralstonia solanacearum strain FJAT15304.F50 plasmid Plas1, complete sequence) position: , mismatch: 8, identity: 0.765

aggacggccagggcggcgcgctgctcttcctcaa	CRISPR spacer
aggacggccagcgcggcgtgctgctgtcgatcct	Protospacer
*********** ******.****** *.  **

146. spacer 34.7|6320299|34|NC_010511|CRISPRCasFinder matches to NZ_CP052107 (Ralstonia solanacearum strain FJAT15249.F50 plasmid Plas1, complete sequence) position: , mismatch: 8, identity: 0.765

aggacggccagggcggcgcgctgctcttcctcaa	CRISPR spacer
aggacggccagcgcggcgtgctgctgtcgatcct	Protospacer
*********** ******.****** *.  **

147. spacer 34.7|6320299|34|NC_010511|CRISPRCasFinder matches to NZ_CP022781 (Ralstonia solanacearum strain SL3822 plasmid unnamed, complete sequence) position: , mismatch: 8, identity: 0.765

aggacggccagggcggcgcgctgctcttcctcaa	CRISPR spacer
aggacggccagcgcggcgtgctgctgtcgatcct	Protospacer
*********** ******.****** *.  **

148. spacer 34.7|6320299|34|NC_010511|CRISPRCasFinder matches to NZ_CP052117 (Ralstonia solanacearum strain FJAT1463.F1 plasmid Plas1, complete sequence) position: , mismatch: 8, identity: 0.765

aggacggccagggcggcgcgctgctcttcctcaa	CRISPR spacer
aggacggccagcgcggcgtgctgctgtcgatcct	Protospacer
*********** ******.****** *.  **

149. spacer 34.7|6320299|34|NC_010511|CRISPRCasFinder matches to NZ_CP052125 (Ralstonia solanacearum strain FJAT1452.F1 plasmid Plas1, complete sequence) position: , mismatch: 8, identity: 0.765

aggacggccagggcggcgcgctgctcttcctcaa	CRISPR spacer
aggacggccagcgcggcgtgctgctgtcgatcct	Protospacer
*********** ******.****** *.  **

150. spacer 34.7|6320299|34|NC_010511|CRISPRCasFinder matches to NZ_CP022793 (Ralstonia solanacearum strain SL2729 plasmid unnamed, complete sequence) position: , mismatch: 8, identity: 0.765

aggacggccagggcggcgcgctgctcttcctcaa	CRISPR spacer
aggacggccagcgcggcgtgctgctgtcgatcct	Protospacer
*********** ******.****** *.  **

151. spacer 34.7|6320299|34|NC_010511|CRISPRCasFinder matches to NZ_CP022785 (Ralstonia solanacearum strain SL3730 plasmid unnamed, complete sequence) position: , mismatch: 8, identity: 0.765

aggacggccagggcggcgcgctgctcttcctcaa	CRISPR spacer
aggacggccagcgcggcgtgctgctgtcgatcct	Protospacer
*********** ******.****** *.  **

152. spacer 34.7|6320299|34|NC_010511|CRISPRCasFinder matches to NZ_CP022787 (Ralstonia solanacearum strain SL3300 plasmid unnamed, complete sequence) position: , mismatch: 8, identity: 0.765

aggacggccagggcggcgcgctgctcttcctcaa	CRISPR spacer
aggacggccagcgcggcgtgctgctgtcgatcct	Protospacer
*********** ******.****** *.  **

153. spacer 34.7|6320299|34|NC_010511|CRISPRCasFinder matches to NZ_CP022756 (Ralstonia solanacearum strain T117 plasmid unnamed, complete sequence) position: , mismatch: 8, identity: 0.765

aggacggccagggcggcgcgctgctcttcctcaa	CRISPR spacer
aggacggccagcgcggcgtgctgctgtcgatcct	Protospacer
*********** ******.****** *.  **

154. spacer 34.7|6320299|34|NC_010511|CRISPRCasFinder matches to NZ_CP052129 (Ralstonia solanacearum strain FJAT1303.F1 plasmid Plas1, complete sequence) position: , mismatch: 8, identity: 0.765

aggacggccagggcggcgcgctgctcttcctcaa	CRISPR spacer
aggacggccagcgcggcgtgctgctgtcgatcct	Protospacer
*********** ******.****** *.  **

155. spacer 34.7|6320299|34|NC_010511|CRISPRCasFinder matches to NZ_CP052121 (Ralstonia solanacearum strain FJAT1458.F1 plasmid Plas1, complete sequence) position: , mismatch: 8, identity: 0.765

aggacggccagggcggcgcgctgctcttcctcaa	CRISPR spacer
aggacggccagcgcggcgtgctgctgtcgatcct	Protospacer
*********** ******.****** *.  **

156. spacer 34.7|6320299|34|NC_010511|CRISPRCasFinder matches to NZ_CP052123 (Ralstonia solanacearum strain FJAT1452.F50 plasmid Plas1, complete sequence) position: , mismatch: 8, identity: 0.765

aggacggccagggcggcgcgctgctcttcctcaa	CRISPR spacer
aggacggccagcgcggcgtgctgctgtcgatcct	Protospacer
*********** ******.****** *.  **

157. spacer 34.7|6320299|34|NC_010511|CRISPRCasFinder matches to NZ_CP052131 (Ralstonia solanacearum strain FJAT1303.F8 plasmid Plas1, complete sequence) position: , mismatch: 8, identity: 0.765

aggacggccagggcggcgcgctgctcttcctcaa	CRISPR spacer
aggacggccagcgcggcgtgctgctgtcgatcct	Protospacer
*********** ******.****** *.  **

158. spacer 34.7|6320299|34|NC_010511|CRISPRCasFinder matches to CP011998 (Ralstonia solanacearum strain YC45 plasmid, complete sequence) position: , mismatch: 8, identity: 0.765

aggacggccagggcggcgcgctgctcttcctcaa	CRISPR spacer
aggacggccagcgcggcgtgctgctgtcgatcct	Protospacer
*********** ******.****** *.  **

159. spacer 34.7|6320299|34|NC_010511|CRISPRCasFinder matches to NZ_CP052073 (Ralstonia solanacearum strain FJAT448.F50 plasmid Plas1, complete sequence) position: , mismatch: 8, identity: 0.765

aggacggccagggcggcgcgctgctcttcctcaa	CRISPR spacer
aggacggccagcgcggcgtgctgctgtcgatcct	Protospacer
*********** ******.****** *.  **

160. spacer 34.7|6320299|34|NC_010511|CRISPRCasFinder matches to NZ_CP052081 (Ralstonia solanacearum strain FJAT442.F50 plasmid Plas1, complete sequence) position: , mismatch: 8, identity: 0.765

aggacggccagggcggcgcgctgctcttcctcaa	CRISPR spacer
aggacggccagcgcggcgtgctgctgtcgatcct	Protospacer
*********** ******.****** *.  **

161. spacer 34.7|6320299|34|NC_010511|CRISPRCasFinder matches to NZ_CP052083 (Ralstonia solanacearum strain FJAT442.F1 plasmid Plas1, complete sequence) position: , mismatch: 8, identity: 0.765

aggacggccagggcggcgcgctgctcttcctcaa	CRISPR spacer
aggacggccagcgcggcgtgctgctgtcgatcct	Protospacer
*********** ******.****** *.  **

162. spacer 34.7|6320299|34|NC_010511|CRISPRCasFinder matches to NZ_CP052109 (Ralstonia solanacearum strain FJAT15249.F1 plasmid Plas1, complete sequence) position: , mismatch: 8, identity: 0.765

aggacggccagggcggcgcgctgctcttcctcaa	CRISPR spacer
aggacggccagcgcggcgtgctgctgtcgatcct	Protospacer
*********** ******.****** *.  **

163. spacer 34.7|6320299|34|NC_010511|CRISPRCasFinder matches to NZ_CP052091 (Ralstonia solanacearum strain FJAT15340.F6 plasmid Plas1, complete sequence) position: , mismatch: 8, identity: 0.765

aggacggccagggcggcgcgctgctcttcctcaa	CRISPR spacer
aggacggccagcgcggcgtgctgctgtcgatcct	Protospacer
*********** ******.****** *.  **

164. spacer 34.7|6320299|34|NC_010511|CRISPRCasFinder matches to NZ_CP052111 (Ralstonia solanacearum strain FJAT15244.F50 plasmid Plas1, complete sequence) position: , mismatch: 8, identity: 0.765

aggacggccagggcggcgcgctgctcttcctcaa	CRISPR spacer
aggacggccagcgcggcgtgctgctgtcgatcct	Protospacer
*********** ******.****** *.  **

165. spacer 34.7|6320299|34|NC_010511|CRISPRCasFinder matches to NZ_CP052103 (Ralstonia solanacearum strain FJAT15252.F50 plasmid Plas1, complete sequence) position: , mismatch: 8, identity: 0.765

aggacggccagggcggcgcgctgctcttcctcaa	CRISPR spacer
aggacggccagcgcggcgtgctgctgtcgatcct	Protospacer
*********** ******.****** *.  **

166. spacer 34.7|6320299|34|NC_010511|CRISPRCasFinder matches to NZ_CP052119 (Ralstonia solanacearum strain FJAT1458.F50 plasmid Plas1, complete sequence) position: , mismatch: 8, identity: 0.765

aggacggccagggcggcgcgctgctcttcctcaa	CRISPR spacer
aggacggccagcgcggcgtgctgctgtcgatcct	Protospacer
*********** ******.****** *.  **

167. spacer 34.7|6320299|34|NC_010511|CRISPRCasFinder matches to NZ_CP052113 (Ralstonia solanacearum strain FJAT15244.F1 plasmid Plas1, complete sequence) position: , mismatch: 8, identity: 0.765

aggacggccagggcggcgcgctgctcttcctcaa	CRISPR spacer
aggacggccagcgcggcgtgctgctgtcgatcct	Protospacer
*********** ******.****** *.  **

168. spacer 34.7|6320299|34|NC_010511|CRISPRCasFinder matches to KT021004 (Thermobifida phage P1312, complete genome) position: , mismatch: 8, identity: 0.765

aggacggccagggcggcgcgctgctcttcctcaa	CRISPR spacer
agcgcggcctgggcggcgcgctgcacttcagctc	Protospacer
** .***** ************** ****  *

169. spacer 34.15|6320843|34|NC_010511|CRISPRCasFinder matches to NZ_CP043960 (Streptomyces tendae strain 139 plasmid unnamed1, complete sequence) position: , mismatch: 8, identity: 0.765

-----cctgcagcagcagcagcgacaccatgtgcgtgtt	CRISPR spacer
gtgtgcctg-----gctggagcgacaccatgtgcgtgtg	Protospacer
     ****     ** * *******************

170. spacer 6.1|725596|32|NC_010511|CRISPRCasFinder matches to NZ_CP024582 (Roseomonas sp. FDAARGOS_362 plasmid unnamed1, complete sequence) position: , mismatch: 9, identity: 0.719

gatgaagacgaccggcagcgtcaagggcacct	CRISPR spacer
ggcagagacgaccagcagcgacaagggcgaca	Protospacer
*....********.****** *******. *

171. spacer 6.1|725596|32|NC_010511|CRISPRCasFinder matches to NZ_CP021028 (Rhizobium sp. TAL182 plasmid pRetTAL182d, complete sequence) position: , mismatch: 9, identity: 0.719

gatgaagacgaccggcagcgtcaagggcacct	CRISPR spacer
aaagaagacgacgggcagcgacaaggaaaaag	Protospacer
.* ********* ******* *****. *

172. spacer 6.1|725596|32|NC_010511|CRISPRCasFinder matches to NZ_CP013503 (Rhizobium esperanzae strain N561 plasmid pRspN561c, complete sequence) position: , mismatch: 9, identity: 0.719

gatgaagacgaccggcagcgtcaagggcacct	CRISPR spacer
aaagaagacgacgggcagcgacaaggaaaaag	Protospacer
.* ********* ******* *****. *

173. spacer 6.1|725596|32|NC_010511|CRISPRCasFinder matches to NZ_CP013509 (Rhizobium sp. N1341 plasmid pRspN1341d, complete sequence) position: , mismatch: 9, identity: 0.719

gatgaagacgaccggcagcgtcaagggcacct	CRISPR spacer
aaagaagacgacgggcagcgacaaggaaaaag	Protospacer
.* ********* ******* *****. *

174. spacer 6.1|725596|32|NC_010511|CRISPRCasFinder matches to NZ_CP013520 (Rhizobium sp. N113 plasmid pRspN113c, complete sequence) position: , mismatch: 9, identity: 0.719

gatgaagacgaccggcagcgtcaagggcacct	CRISPR spacer
aaagaagacgacgggcagcgacaaggaaaaag	Protospacer
.* ********* ******* *****. *

175. spacer 6.1|725596|32|NC_010511|CRISPRCasFinder matches to NZ_CP013493 (Rhizobium sp. N6212 plasmid pRspN6212c, complete sequence) position: , mismatch: 9, identity: 0.719

gatgaagacgaccggcagcgtcaagggcacct	CRISPR spacer
aaagaagacgacgggcagcgacaaggaaaaag	Protospacer
.* ********* ******* *****. *

176. spacer 6.1|725596|32|NC_010511|CRISPRCasFinder matches to NZ_CP013516 (Rhizobium sp. N1314 plasmid pRspN1314e, complete sequence) position: , mismatch: 9, identity: 0.719

gatgaagacgaccggcagcgtcaagggcacct	CRISPR spacer
aaagaagacgacgggcagcgacaaggaaaaag	Protospacer
.* ********* ******* *****. *

177. spacer 6.1|725596|32|NC_010511|CRISPRCasFinder matches to NZ_CP023068 (Ensifer sojae CCBAU 05684 plasmid pSJ05684b, complete sequence) position: , mismatch: 9, identity: 0.719

gatgaagacgaccggcagcgtcaagggcacct	CRISPR spacer
gtccccgacgaccgtcagcgtccagggcagat	Protospacer
* .   ******** ******* ******  *

178. spacer 11.5|1944081|34|NC_010511|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP054616 (Azospirillum oryzae strain KACC 14407 plasmid unnamed2, complete sequence) position: , mismatch: 9, identity: 0.735

gccgtcggcgcctggtcgctgcccggcgacacgc	CRISPR spacer
gtccgccgctcctggtcgcagcccggcgacagcg	Protospacer
*.*  * ** ********* ***********

179. spacer 14.2|2625230|34|NC_010511|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP016365 (Phaeobacter porticola strain P97 plasmid pP97_a, complete sequence) position: , mismatch: 9, identity: 0.735

tgtctccgtccgcctacaacgggttgatcacccg	CRISPR spacer
ctccaccgtccgcctacaagggcttgatcttgcg	Protospacer
. .* ************** ** ****** . **

180. spacer 17.1|3091259|31|NC_010511|CRISPRCasFinder matches to NC_021289 (Burkholderia insecticola plasmid p1, complete sequence) position: , mismatch: 9, identity: 0.71

tgcgaagcaatccgtcggatgtcgtatccca	CRISPR spacer
gggcgagcaattcgtcggatgtcggatcgat	Protospacer
 *  .******.************ ***

181. spacer 28.1|4448455|35|NC_010511|CRISPRCasFinder matches to NZ_AP014705 (Methylobacterium aquaticum strain MA-22A plasmid pMaq22A_1p, complete sequence) position: , mismatch: 9, identity: 0.743

ccaatccgcattgcgacgcaatccgtcggatcacg	CRISPR spacer
ggtttccgcattgcgaagcaatcagtcggaaatcg	Protospacer
    ************ ****** ******   **

182. spacer 34.1|6319896|34|NC_010511|CRISPRCasFinder matches to NZ_CP006990 (Rhizobium sp. IE4771 plasmid pRetIE4771d, complete sequence) position: , mismatch: 9, identity: 0.735

cggcgccggccttgccgtcctttagcgcctgaca-----	CRISPR spacer
cggcgccgaccttgccggccttta-----caacagcaag	Protospacer
********.******** ******     ..***

183. spacer 34.7|6320299|34|NC_010511|CRISPRCasFinder matches to MH588547 (Caulobacter phage CcrSC, complete genome) position: , mismatch: 9, identity: 0.735

aggacggccagggcggcgcgctgctcttcctcaa	CRISPR spacer
tcgacggccacggcggcgcgctgctctcgatggc	Protospacer
  ******** ****************.  * .

184. spacer 34.7|6320299|34|NC_010511|CRISPRCasFinder matches to NC_016591 (Burkholderia sp. YI23 plasmid byi_2p, complete sequence) position: , mismatch: 9, identity: 0.735

aggacggccagggcggcgcgctgctcttcctcaa	CRISPR spacer
cactcggccagggcgccgcgctggtcttcggcga	Protospacer
 .  *********** ******* *****  *.*

185. spacer 34.7|6320299|34|NC_010511|CRISPRCasFinder matches to NZ_CP010418 (Azotobacter chroococcum NCIMB 8003 plasmid pAcX50c, complete sequence) position: , mismatch: 9, identity: 0.735

aggacggccagggcggcgcgctgctcttcctcaa	CRISPR spacer
cgggccagcagggcggcgcgctgctcggcctcct	Protospacer
 **.* . ******************  ****

186. spacer 34.7|6320299|34|NC_010511|CRISPRCasFinder matches to NC_013855 (Azospirillum sp. B510 plasmid pAB510a, complete sequence) position: , mismatch: 9, identity: 0.735

aggacggccagggcggcgcgctgctcttcctcaa	CRISPR spacer
aggtcggccagggcggcgcgcagccgctccggct	Protospacer
*** ***************** **. .***

187. spacer 34.7|6320299|34|NC_010511|CRISPRCasFinder matches to NZ_MF996511 (Bacillus glycinifermentans strain KBN06P03352 plasmid unnamed3, complete sequence) position: , mismatch: 9, identity: 0.735

aggacggccagggcggcgcgctgctcttcctcaa	CRISPR spacer
tgatcgaccagggcggcacgctgctcttggttca	Protospacer
 *. **.**********.**********  *. *

188. spacer 34.9|6320433|35|NC_010511|CRISPRCasFinder matches to NZ_HG938356 (Neorhizobium galegae bv. officinalis bv. officinalis str. HAMBI 1141 plasmid pHAMBI1141a, complete sequence) position: , mismatch: 9, identity: 0.743

cgcccgccgctcgtctacgtggtggccgcggtgga	CRISPR spacer
cgaccgccgctcgactacgtggtggcgatgatccg	Protospacer
** ********** ************ ..*.*  .

189. spacer 34.14|6320775|35|NC_010511|CRISPRCasFinder matches to NZ_CP029588 (Klebsiella pneumoniae strain DA33141 plasmid pDA33141-217, complete sequence) position: , mismatch: 9, identity: 0.743

gcgccctgccgcccggctggcgcgccctgaccgag	CRISPR spacer
cctcagggccgcccggctggcgcgcaatgaccgca	Protospacer
 * *   ******************  ****** .

190. spacer 34.14|6320775|35|NC_010511|CRISPRCasFinder matches to NZ_CP036302 (Klebsiella pneumoniae subsp. pneumoniae strain WCHKP015093 plasmid p1_015093, complete sequence) position: , mismatch: 9, identity: 0.743

gcgccctgccgcccggctggcgcgccctgaccgag	CRISPR spacer
cctcagggccgcccggctggcgcgcaatgaccgca	Protospacer
 * *   ******************  ****** .

191. spacer 34.14|6320775|35|NC_010511|CRISPRCasFinder matches to CP052405 (Klebsiella pneumoniae strain C17KP0020 plasmid pC17KP0020-1, complete sequence) position: , mismatch: 9, identity: 0.743

gcgccctgccgcccggctggcgcgccctgaccgag	CRISPR spacer
cctcagggccgcccggctggcgcgcaatgaccgca	Protospacer
 * *   ******************  ****** .

192. spacer 34.14|6320775|35|NC_010511|CRISPRCasFinder matches to NZ_CP041949 (Klebsiella pneumoniae strain KP2 plasmid pKP2_3, complete sequence) position: , mismatch: 9, identity: 0.743

gcgccctgccgcccggctggcgcgccctgaccgag	CRISPR spacer
cctcagggccgcccggctggcgcgcaatgaccgca	Protospacer
 * *   ******************  ****** .

193. spacer 34.14|6320775|35|NC_010511|CRISPRCasFinder matches to CP052218 (Klebsiella pneumoniae strain E17KP0053 plasmid pE17KP0053-1, complete sequence) position: , mismatch: 9, identity: 0.743

gcgccctgccgcccggctggcgcgccctgaccgag	CRISPR spacer
cctcagggccgcccggctggcgcgcaatgaccgca	Protospacer
 * *   ******************  ****** .

194. spacer 34.14|6320775|35|NC_010511|CRISPRCasFinder matches to NZ_CP036337 (Klebsiella pneumoniae strain BP327 plasmid pIncFIBK, complete sequence) position: , mismatch: 9, identity: 0.743

gcgccctgccgcccggctggcgcgccctgaccgag	CRISPR spacer
cctcagggccgcccggctggcgcgcaatgaccgca	Protospacer
 * *   ******************  ****** .

195. spacer 34.14|6320775|35|NC_010511|CRISPRCasFinder matches to NZ_CP039809 (Klebsiella pneumoniae strain C2660 plasmid pC2660-2, complete sequence) position: , mismatch: 9, identity: 0.743

gcgccctgccgcccggctggcgcgccctgaccgag	CRISPR spacer
cctcagggccgcccggctggcgcgcaatgaccgca	Protospacer
 * *   ******************  ****** .

196. spacer 34.14|6320775|35|NC_010511|CRISPRCasFinder matches to NZ_CP033402 (Klebsiella pneumoniae strain WCHKP115069 plasmid p1_115069, complete sequence) position: , mismatch: 9, identity: 0.743

gcgccctgccgcccggctggcgcgccctgaccgag	CRISPR spacer
cctcagggccgcccggctggcgcgcaatgaccgca	Protospacer
 * *   ******************  ****** .

197. spacer 34.14|6320775|35|NC_010511|CRISPRCasFinder matches to NZ_CP029830 (Azospirillum ramasamyi strain M2T2B2 plasmid unnamed1, complete sequence) position: , mismatch: 9, identity: 0.743

gcgccctgccgcccggctggcgcgccctgaccgag	CRISPR spacer
ccgccctgccgcccgcctggcccgcccctacgatc	Protospacer
 ************** ***** *****. ** .

198. spacer 34.14|6320775|35|NC_010511|CRISPRCasFinder matches to NZ_CP029387 (Klebsiella pneumoniae subsp. pneumoniae strain SCKP040074 plasmid pTetD_040074, complete sequence) position: , mismatch: 9, identity: 0.743

gcgccctgccgcccggctggcgcgccctgaccgag	CRISPR spacer
cctcagggccgcccggctggcgcgcaatgaccgca	Protospacer
 * *   ******************  ****** .

199. spacer 34.14|6320775|35|NC_010511|CRISPRCasFinder matches to NZ_LR025093 (Klebsiella pneumoniae isolate KP9201 plasmid 2, complete sequence) position: , mismatch: 9, identity: 0.743

gcgccctgccgcccggctggcgcgccctgaccgag	CRISPR spacer
cctcagggccgcccggctggcgcgcaatgaccgca	Protospacer
 * *   ******************  ****** .

200. spacer 34.14|6320775|35|NC_010511|CRISPRCasFinder matches to NZ_CP042883 (Klebsiella pneumoniae strain NMBU-W07E18 plasmid pNMBU-W07E18_01, complete sequence) position: , mismatch: 9, identity: 0.743

gcgccctgccgcccggctggcgcgccctgaccgag	CRISPR spacer
cctcagggccgcccggctggcgcgcaatgaccgca	Protospacer
 * *   ******************  ****** .

201. spacer 34.14|6320775|35|NC_010511|CRISPRCasFinder matches to CP052435 (Klebsiella pneumoniae strain C16KP0108 plasmid pC16KP0108-1, complete sequence) position: , mismatch: 9, identity: 0.743

gcgccctgccgcccggctggcgcgccctgaccgag	CRISPR spacer
cctcagggccgcccggctggcgcgcaatgaccgca	Protospacer
 * *   ******************  ****** .

202. spacer 34.14|6320775|35|NC_010511|CRISPRCasFinder matches to NZ_LT994840 (Klebsiella pneumoniae isolate CNR48 plasmid CNR48, complete sequence) position: , mismatch: 9, identity: 0.743

gcgccctgccgcccggctggcgcgccctgaccgag	CRISPR spacer
cctcagggccgcccggctggcgcgcaatgaccgca	Protospacer
 * *   ******************  ****** .

203. spacer 34.14|6320775|35|NC_010511|CRISPRCasFinder matches to NZ_CP041928 (Klebsiella pneumoniae strain 18-2374 plasmid pSECR18-2374A, complete sequence) position: , mismatch: 9, identity: 0.743

gcgccctgccgcccggctggcgcgccctgaccgag	CRISPR spacer
cctcagggccgcccggctggcgcgcaatgaccgca	Protospacer
 * *   ******************  ****** .

204. spacer 34.14|6320775|35|NC_010511|CRISPRCasFinder matches to NC_023332 (Klebsiella pneumoniae strain ST48 plasmid pKP09085, complete sequence) position: , mismatch: 9, identity: 0.743

gcgccctgccgcccggctggcgcgccctgaccgag	CRISPR spacer
cctcagggccgcccggctggcgcgcaatgaccgca	Protospacer
 * *   ******************  ****** .

205. spacer 34.14|6320775|35|NC_010511|CRISPRCasFinder matches to NC_023333 (Klebsiella pneumoniae strain ST23 plasmid pKP007, complete sequence) position: , mismatch: 9, identity: 0.743

gcgccctgccgcccggctggcgcgccctgaccgag	CRISPR spacer
cctcagggccgcccggctggcgcgcaatgaccgca	Protospacer
 * *   ******************  ****** .

206. spacer 34.14|6320775|35|NC_010511|CRISPRCasFinder matches to NC_023334 (Klebsiella pneumoniae strain ST15 plasmid pKP02022, complete sequence) position: , mismatch: 9, identity: 0.743

gcgccctgccgcccggctggcgcgccctgaccgag	CRISPR spacer
cctcagggccgcccggctggcgcgcaatgaccgca	Protospacer
 * *   ******************  ****** .

207. spacer 34.14|6320775|35|NC_010511|CRISPRCasFinder matches to NZ_CP029591 (Klebsiella pneumoniae strain DA33144 plasmid pDA33144-220, complete sequence) position: , mismatch: 9, identity: 0.743

gcgccctgccgcccggctggcgcgccctgaccgag	CRISPR spacer
cctcagggccgcccggctggcgcgcaatgaccgca	Protospacer
 * *   ******************  ****** .

208. spacer 34.14|6320775|35|NC_010511|CRISPRCasFinder matches to NC_016966 (Klebsiella pneumoniae plasmid pUUH239.2, complete sequence) position: , mismatch: 9, identity: 0.743

gcgccctgccgcccggctggcgcgccctgaccgag	CRISPR spacer
cctcagggccgcccggctggcgcgcaatgaccgca	Protospacer
 * *   ******************  ****** .

209. spacer 34.14|6320775|35|NC_010511|CRISPRCasFinder matches to NZ_CP012572 (Klebsiella pneumoniae strain UCLAOXA232KP plasmid pUCLAOXA232-6.X, complete sequence) position: , mismatch: 9, identity: 0.743

gcgccctgccgcccggctggcgcgccctgaccgag	CRISPR spacer
cctcagggccgcccggctggcgcgcaatgaccgca	Protospacer
 * *   ******************  ****** .

210. spacer 34.14|6320775|35|NC_010511|CRISPRCasFinder matches to NZ_CP041640 (Klebsiella pneumoniae strain PIMB15ND2KP27 plasmid pKP27-MPH, complete sequence) position: , mismatch: 9, identity: 0.743

gcgccctgccgcccggctggcgcgccctgaccgag	CRISPR spacer
cctcagggccgcccggctggcgcgcaatgaccgca	Protospacer
 * *   ******************  ****** .

211. spacer 34.14|6320775|35|NC_010511|CRISPRCasFinder matches to NZ_CP012567 (Klebsiella pneumoniae strain UCLAOXA232KP plasmid pUCLAOXA232-6, complete sequence) position: , mismatch: 9, identity: 0.743

gcgccctgccgcccggctggcgcgccctgaccgag	CRISPR spacer
cctcagggccgcccggctggcgcgcaatgaccgca	Protospacer
 * *   ******************  ****** .

212. spacer 34.14|6320775|35|NC_010511|CRISPRCasFinder matches to NZ_CP050379 (Klebsiella pneumoniae strain 51015 plasmid p51015_CTX_M_15, complete sequence) position: , mismatch: 9, identity: 0.743

gcgccctgccgcccggctggcgcgccctgaccgag	CRISPR spacer
cctcagggccgcccggctggcgcgcaatgaccgca	Protospacer
 * *   ******************  ****** .

213. spacer 34.14|6320775|35|NC_010511|CRISPRCasFinder matches to NZ_CP050374 (Klebsiella pneumoniae strain 50595 plasmid p50595_NDM_1, complete sequence) position: , mismatch: 9, identity: 0.743

gcgccctgccgcccggctggcgcgccctgaccgag	CRISPR spacer
cctcagggccgcccggctggcgcgcaatgaccgca	Protospacer
 * *   ******************  ****** .

214. spacer 34.14|6320775|35|NC_010511|CRISPRCasFinder matches to NZ_CP020903 (Klebsiella pneumoniae strain K66-45 plasmid pK66-45-2, complete sequence) position: , mismatch: 9, identity: 0.743

gcgccctgccgcccggctggcgcgccctgaccgag	CRISPR spacer
cctcagggccgcccggctggcgcgcaatgaccgca	Protospacer
 * *   ******************  ****** .

215. spacer 34.14|6320775|35|NC_010511|CRISPRCasFinder matches to NZ_CP032186 (Klebsiella pneumoniae strain AR_0075 plasmid unnamed1, complete sequence) position: , mismatch: 9, identity: 0.743

gcgccctgccgcccggctggcgcgccctgaccgag	CRISPR spacer
cctcagggccgcccggctggcgcgcaatgaccgca	Protospacer
 * *   ******************  ****** .

216. spacer 34.14|6320775|35|NC_010511|CRISPRCasFinder matches to NZ_LR025089 (Klebsiella pneumoniae isolate KP980 plasmid 2, complete sequence) position: , mismatch: 9, identity: 0.743

gcgccctgccgcccggctggcgcgccctgaccgag	CRISPR spacer
cctcagggccgcccggctggcgcgcaatgaccgca	Protospacer
 * *   ******************  ****** .

217. spacer 34.14|6320775|35|NC_010511|CRISPRCasFinder matches to NZ_CP036188 (Klebsiella pneumoniae strain BA1559 plasmid pIncFIBK, complete sequence) position: , mismatch: 9, identity: 0.743

gcgccctgccgcccggctggcgcgccctgaccgag	CRISPR spacer
cctcagggccgcccggctggcgcgcaatgaccgca	Protospacer
 * *   ******************  ****** .

218. spacer 34.14|6320775|35|NC_010511|CRISPRCasFinder matches to NZ_MN268580 (Klebsiella pneumoniae strain KP13-53 plasmid pKP13-53-tet(A), complete sequence) position: , mismatch: 9, identity: 0.743

gcgccctgccgcccggctggcgcgccctgaccgag	CRISPR spacer
cctcagggccgcccggctggcgcgcaatgaccgca	Protospacer
 * *   ******************  ****** .

219. spacer 34.14|6320775|35|NC_010511|CRISPRCasFinder matches to NC_013858 (Azospirillum sp. B510 plasmid pAB510d, complete sequence) position: , mismatch: 9, identity: 0.743

gcgccctgccgcccggctggcgcgccctgaccgag	CRISPR spacer
ctgccaggccgcccggctggcgcgccccgccatgg	Protospacer
 .***  ********************.* *  .*

220. spacer 34.23|6320293|40|NC_010511|CRT,PILER-CR matches to NZ_CP025613 (Niveispirillum cyanobacteriorum strain TH16 plasmid unnamed1, complete sequence) position: , mismatch: 9, identity: 0.775

tgaaccaggacggccagggcggcgcgctgctcttcctcaa	CRISPR spacer
tgaactatgacggccagggcggcgcgctgaccagccagat	Protospacer
*****.* ********************* .*  **  *

221. spacer 11.4|1944015|35|NC_010511|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP034352 (Streptomyces sp. W1SF4 plasmid p2, complete sequence) position: , mismatch: 10, identity: 0.714

aaggcgaccgtgcccgcgatcatcgaggtgcggtg	CRISPR spacer
ggcatcaccgtgcccgcgatcgtggaggtgccgag	Protospacer
.. .. ***************.* ******* * *

222. spacer 24.1|4168034|33|NC_010511|CRISPRCasFinder matches to NC_011892 (Methylobacterium nodulans ORS 2060 plasmid pMNOD01, complete sequence) position: , mismatch: 10, identity: 0.697

acgtatgacaagcccgcgcggcgcctgagcgaa	CRISPR spacer
cctcgctgcaaccccgcgcggcccctgagcgag	Protospacer
 * ... .*** ********** *********.

223. spacer 34.5|6320165|33|NC_010511|CRISPRCasFinder matches to NZ_CP032346 (Azospirillum brasilense strain MTCC4039 plasmid p1, complete sequence) position: , mismatch: 10, identity: 0.697

gggatggcccctcggccagcacgcgtcgcagga	CRISPR spacer
ccgtcacgccctcggccagcagccgtcgcaggc	Protospacer
  * ..  *************  *********

224. spacer 34.7|6320299|34|NC_010511|CRISPRCasFinder matches to NC_013856 (Azospirillum sp. B510 plasmid pAB510b, complete sequence) position: , mismatch: 10, identity: 0.706

aggacggccagggcggcgcgctgctcttcctcaa	CRISPR spacer
tcctcggccagggcggcgcgctgcgcctcccgcg	Protospacer
    ******************** *.***.  .

225. spacer 34.7|6320299|34|NC_010511|CRISPRCasFinder matches to NC_016586 (Azospirillum lipoferum 4B plasmid AZO_p2, complete sequence) position: , mismatch: 10, identity: 0.706

aggacggccagggcggcgcgctgctcttcctcaa	CRISPR spacer
tcctcggccagggcggagcgctgcgcttcccgcg	Protospacer
    ************ ******* *****.  .

226. spacer 34.7|6320299|34|NC_010511|CRISPRCasFinder matches to NC_018022 (Mycolicibacterium chubuense NBB4 plasmid pMYCCH.01, complete sequence) position: , mismatch: 10, identity: 0.706

aggacggccagggcggcgcgctgctcttcctcaa	CRISPR spacer
gggtcggccaggacggcgcgctgctccggggtca	Protospacer
.** ********.*************.    . *

227. spacer 34.7|6320299|34|NC_010511|CRISPRCasFinder matches to NZ_CP015867 (Streptomyces parvulus strain 2297 plasmid pSPA1, complete sequence) position: , mismatch: 10, identity: 0.706

aggacggccagggcggcgcgctgctcttcctcaa	CRISPR spacer
aggtcggccagggcggcgcgcagcggctcgcggt	Protospacer
*** ***************** **  .** . .

228. spacer 34.7|6320299|34|NC_010511|CRISPRCasFinder matches to NZ_CP029092 (Pseudomonas aeruginosa strain AR441 plasmid unnamed2, complete sequence) position: , mismatch: 10, identity: 0.706

aggacggccagggcggcgcgctgctcttcctcaa	CRISPR spacer
ccggaggcctgggcggcgccctgctcttctaccg	Protospacer
  *. **** ********* *********. * .

229. spacer 34.7|6320299|34|NC_010511|CRISPRCasFinder matches to NZ_CP027168 (Pseudomonas aeruginosa strain AR_0356 plasmid unnamed1, complete sequence) position: , mismatch: 10, identity: 0.706

aggacggccagggcggcgcgctgctcttcctcaa	CRISPR spacer
ccggaggcctgggcggcgccctgctcttctaccg	Protospacer
  *. **** ********* *********. * .

230. spacer 34.7|6320299|34|NC_010511|CRISPRCasFinder matches to NZ_AP014579 (Burkholderia sp. RPE67 plasmid p1, complete sequence) position: , mismatch: 10, identity: 0.706

aggacggccagggcggcgcgctgctcttcctcaa	CRISPR spacer
gcgacggccagcgcgccgcgctgctcgcgcagac	Protospacer
. ********* *** ********** . *  *

231. spacer 34.14|6320775|35|NC_010511|CRISPRCasFinder matches to NZ_CP054842 (Acidovorax sp. 16-35-5 plasmid unnamed2, complete sequence) position: , mismatch: 10, identity: 0.714

gcgccctgccgcccggctggcgcgccctgaccgag-------	CRISPR spacer
gccccctgccgcccgggtggcgcg-------caagtcgctgt	Protospacer
** ************* *******       *.**

232. spacer 34.16|6320910|35|NC_010511|CRISPRCasFinder matches to NC_016586 (Azospirillum lipoferum 4B plasmid AZO_p2, complete sequence) position: , mismatch: 10, identity: 0.714

ccgcccgcgcccgtcgcgcgccacgcggtgtcggc	CRISPR spacer
ggtgccgcgcccgtcgagcgccgcgcggtagccgt	Protospacer
    ************ *****.******. * *.

233. spacer 11.4|1944015|35|NC_010511|PILER-CR,CRISPRCasFinder,CRT matches to NC_017957 (Tistrella mobilis KA081020-065 plasmid pTM1, complete sequence) position: , mismatch: 11, identity: 0.686

aaggcgaccgtgcccgcgatcatcgaggtgcggtg	CRISPR spacer
ggcgcgaccgagcccgagatcatcgaggccgcccg	Protospacer
.. ******* ***** ***********.    .*

234. spacer 11.5|1944081|34|NC_010511|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP054606 (Sulfitobacter pseudonitzschiae strain H46 plasmid unnamed7, complete sequence) position: , mismatch: 11, identity: 0.676

gccgtcggcgcctggtcgctgcccggcgacacgc	CRISPR spacer
ctgatcggcgcctgggcgctggccggcgggcagg	Protospacer
 . .*********** ***** ******.   *

235. spacer 11.5|1944081|34|NC_010511|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP020399 (Burkholderia multivorans strain FDAARGOS_246 plasmid unnamed, complete sequence) position: , mismatch: 11, identity: 0.676

gccgtcggcgcctggtcgctgcccggcgacacgc	CRISPR spacer
tgcagatgcgcatagtcgctgcccggcgacagcg	Protospacer
  *.   **** *.*****************

236. spacer 34.7|6320299|34|NC_010511|CRISPRCasFinder matches to NC_017791 (Deinococcus gobiensis I-0 plasmid P2, complete sequence) position: , mismatch: 11, identity: 0.676

aggacggccagggcggcgcgctgctcttcctcaa	CRISPR spacer
ccccataccggggcggcgcgctgctcttcttctc	Protospacer
      .**.*******************.**

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

1551804 : 1634499

Staphylococcus_phage(22.22%)

transposase,integrase,tRNA

attL 1572058:1572074|attR 1641582:1641598

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_012331344.1\|1551804_1553118_-\|tRNA	tRNA uridine-5-carboxymethylaminomethyl(34) synthesis GTPase MnmE	NA	NA	NA	NA
WP_012331345.1\|1553318_1555193_+	glucans biosynthesis glucosyltransferase MdoH	NA	NA	NA	NA
WP_012331346.1\|1555311_1555776_-	hypothetical protein	NA	NA	NA	NA
WP_012331347.1\|1556089_1557250_-	PLP-dependent transferase	NA	NA	NA	NA
WP_012331348.1\|1557331_1557844_+	tryptophan-rich sensory protein	A0A1V0S976	Catovirus	6.6e-06	25.2
WP_012331349.1\|1558000_1558918_+	polyphosphate kinase 2	NA	NA	NA	NA
WP_012331350.1\|1559035_1561309_-	xanthine dehydrogenase family protein molybdopterin-binding subunit	NA	NA	NA	NA
WP_012331351.1\|1561320_1561767_-	(2Fe-2S)-binding protein	NA	NA	NA	NA
WP_012331352.1\|1562064_1562331_-	hypothetical protein	NA	NA	NA	NA
WP_012331353.1\|1562397_1563222_-	aldo/keto reductase	A0A2H4PQR8	Staphylococcus_phage	4.8e-59	44.5
WP_012331354.1\|1563302_1564514_-	ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_043702119.1\|1564659_1565994_-	hypothetical protein	NA	NA	NA	NA
WP_012331356.1\|1566055_1567171_-	hypothetical protein	NA	NA	NA	NA
WP_012331357.1\|1567236_1568403_-	hypothetical protein	NA	NA	NA	NA
WP_012331358.1\|1569003_1569417_-	peptide-methionine (R)-S-oxide reductase MsrB	NA	NA	NA	NA
WP_012331359.1\|1569486_1570647_-	YihY/virulence factor BrkB family protein	NA	NA	NA	NA
WP_012331360.1\|1570855_1571734_-	NAD(P)-dependent oxidoreductase	NA	NA	NA	NA
WP_012331361.1\|1571832_1572270_-	hypothetical protein	NA	NA	NA	NA
1572058:1572074	attL	NA	NA	NA	NA
WP_012331362.1\|1572454_1573303_-	pyridoxal kinase PdxY	NA	NA	NA	NA
WP_012331363.1\|1573432_1573954_+	DedA family protein	NA	NA	NA	NA
WP_012331364.1\|1574167_1575166_-	ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_012331365.1\|1575384_1576167_-	ABC transporter permease	NA	NA	NA	NA
WP_012331366.1\|1576243_1577122_-	ABC transporter ATP-binding protein	W8CYL7	Bacillus_phage	3.4e-10	26.9
WP_012331367.1\|1577188_1577374_-	hypothetical protein	NA	NA	NA	NA
WP_012331368.1\|1577370_1578501_-	PepSY domain-containing protein	NA	NA	NA	NA
WP_050777552.1\|1578512_1580711_-	TonB-dependent siderophore receptor	NA	NA	NA	NA
WP_012331370.1\|1581080_1581557_+	MmcB family DNA repair protein	NA	NA	NA	NA
WP_012331371.1\|1581678_1582428_+	SDR family oxidoreductase	NA	NA	NA	NA
WP_012331372.1\|1582424_1583201_-	AAA family ATPase	NA	NA	NA	NA
WP_012331373.1\|1583351_1584266_+	PhzF family phenazine biosynthesis protein	NA	NA	NA	NA
WP_012331374.1\|1584262_1584973_+	NUDIX hydrolase	NA	NA	NA	NA
WP_012331375.1\|1585038_1585326_-	hypothetical protein	NA	NA	NA	NA
WP_012331376.1\|1585439_1585763_-	hypothetical protein	NA	NA	NA	NA
WP_012331377.1\|1586209_1587769_+	2-isopropylmalate synthase	E5EQ69	Micromonas_sp._RCC1109_virus	9.0e-06	25.7
WP_012330561.1\|1588542_1589943_+\|transposase	IS30-like element ISMtsp4 family transposase	W5R8L2	Staphylococcus_phage	1.4e-26	36.0
WP_083784641.1\|1590775_1591201_+	hypothetical protein	NA	NA	NA	NA
WP_168169138.1\|1591344_1592145_+	Crp/Fnr family transcriptional regulator	NA	NA	NA	NA
WP_012331379.1\|1593085_1594006_+	glucose-1-phosphate thymidylyltransferase RfbA	I7I009	Enterobacteria_phage	1.2e-93	55.9
WP_168169139.1\|1594045_1594540_+\|transposase	IS3 family transposase	U5P429	Shigella_phage	6.8e-08	34.9
WP_012331380.1\|1595021_1596020_-\|transposase	IS110-like element ISMtsp7 family transposase	NA	NA	NA	NA
WP_168169121.1\|1596164_1596305_+	hypothetical protein	NA	NA	NA	NA
WP_012331381.1\|1596948_1599399_+	DUF1972 domain-containing protein	NA	NA	NA	NA
WP_012331382.1\|1599419_1600535_+	glycosyltransferase family 4 protein	NA	NA	NA	NA
WP_150108597.1\|1600531_1602292_+	hypothetical protein	NA	NA	NA	NA
WP_012331384.1\|1602288_1603581_+	hypothetical protein	NA	NA	NA	NA
WP_150108598.1\|1603742_1605377_+	formyl transferase	NA	NA	NA	NA
WP_012331386.1\|1605532_1606696_+	ATP-grasp enzyme-like protein	NA	NA	NA	NA
WP_085984485.1\|1607014_1607401_+	hypothetical protein	NA	NA	NA	NA
WP_012290057.1\|1608536_1609412_-	ATP-binding protein	U5N3V8	Enterobacteria_phage	2.1e-52	45.6
WP_012290058.1\|1609408_1610692_-\|transposase	IS21-like element ISMtsp8 family transposase	A0A2L1IVA1	Escherichia_phage	1.6e-45	35.9
WP_043700930.1\|1611138_1611651_+	excisionase family DNA-binding protein	NA	NA	NA	NA
WP_012331388.1\|1612067_1613024_+	hypothetical protein	NA	NA	NA	NA
WP_150108599.1\|1614134_1622417_+	hypothetical protein	NA	NA	NA	NA
WP_012331391.1\|1622413_1628305_+	hypothetical protein	NA	NA	NA	NA
WP_168169140.1\|1628810_1628966_+	hypothetical protein	NA	NA	NA	NA
WP_150108600.1\|1629225_1629639_+\|transposase	transposase	NA	NA	NA	NA
WP_012331393.1\|1629635_1629992_+	IS66 family insertion sequence element accessory protein TnpB	NA	NA	NA	NA
WP_012331395.1\|1631683_1632202_+	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_012331396.1\|1632249_1632780_+	hypothetical protein	NA	NA	NA	NA
WP_012331397.1\|1632909_1634499_+\|integrase	tyrosine-type recombinase/integrase	NA	NA	NA	NA
1641582:1641598	attR	NA	NA	NA	NA

DBSCAN-SWA_2

3067002 : 3124768

Bacillus_phage(20.0%)

transposase,integrase,tRNA

attL 3119243:3119302|attR 3137680:3137763

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_012332602.1\|3067002_3067944_+\|tRNA	glycine--tRNA ligase subunit alpha	NA	NA	NA	NA
WP_012332603.1\|3068035_3070150_+\|tRNA	glycine--tRNA ligase subunit beta	NA	NA	NA	NA
WP_012332604.1\|3070514_3072278_-	hypothetical protein	NA	NA	NA	NA
WP_012332607.1\|3073218_3073527_+	hypothetical protein	NA	NA	NA	NA
WP_012332608.1\|3073810_3074005_-	hypothetical protein	NA	NA	NA	NA
WP_043701194.1\|3074613_3075408_+	methyltransferase domain-containing protein	NA	NA	NA	NA
WP_012332610.1\|3075488_3075644_-	hypothetical protein	NA	NA	NA	NA
WP_012332611.1\|3075906_3076092_+	hypothetical protein	NA	NA	NA	NA
WP_012332612.1\|3076100_3076319_-	hypothetical protein	NA	NA	NA	NA
WP_012332613.1\|3076569_3076725_+	hypothetical protein	NA	NA	NA	NA
WP_012332614.1\|3076801_3077047_-	hypothetical protein	NA	NA	NA	NA
WP_012332615.1\|3077384_3078092_+	hypothetical protein	NA	NA	NA	NA
WP_012332616.1\|3078143_3078731_-	hypothetical protein	NA	NA	NA	NA
WP_150108830.1\|3079702_3080500_-	FkbM family methyltransferase	A0A2N9QVW1	Dishui_lake_phycodnavirus	3.9e-13	36.5
WP_018260759.1\|3080780_3081071_+	hypothetical protein	NA	NA	NA	NA
WP_012332619.1\|3081661_3082501_+	class I SAM-dependent methyltransferase	NA	NA	NA	NA
WP_150108646.1\|3083097_3083352_-	hypothetical protein	NA	NA	NA	NA
WP_012332620.1\|3083478_3084456_+	AraC family transcriptional regulator	NA	NA	NA	NA
WP_012332621.1\|3084667_3084850_-	hypothetical protein	NA	NA	NA	NA
WP_012332622.1\|3085229_3086750_+	aldehyde dehydrogenase family protein	NA	NA	NA	NA
WP_168169153.1\|3087418_3088657_+	amidase	NA	NA	NA	NA
WP_168169154.1\|3088698_3089628_+	zinc ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_012332625.1\|3089624_3091025_+	metal ABC transporter permease	NA	NA	NA	NA
WP_083784805.1\|3091216_3091399_-	hypothetical protein	NA	NA	NA	NA
WP_012332626.1\|3092751_3092964_+	hypothetical protein	NA	NA	NA	NA
WP_012332628.1\|3094044_3094611_-	c-type cytochrome	NA	NA	NA	NA
WP_012332629.1\|3094667_3095717_-	sorbosone dehydrogenase family protein	NA	NA	NA	NA
WP_012332630.1\|3096829_3097012_-	hypothetical protein	NA	NA	NA	NA
WP_012332631.1\|3097318_3097780_-	cupin domain-containing protein	NA	NA	NA	NA
WP_012332632.1\|3097908_3099441_+	transcriptional regulator	NA	NA	NA	NA
WP_085984491.1\|3099795_3100632_+\|transposase	IS5 family transposase	A0A0N9SHJ4	Paenibacillus_phage	3.2e-26	50.0
WP_012332633.1\|3100704_3101829_+\|transposase	IS630 family transposase	NA	NA	NA	NA
WP_012332634.1\|3102143_3102767_+	DsbA family oxidoreductase	NA	NA	NA	NA
WP_043702390.1\|3102775_3104050_-	response regulator	NA	NA	NA	NA
WP_012290057.1\|3104090_3104966_-	ATP-binding protein	U5N3V8	Enterobacteria_phage	2.1e-52	45.6
WP_012290058.1\|3104962_3106246_-\|transposase	IS21-like element ISMtsp8 family transposase	A0A2L1IVA1	Escherichia_phage	1.6e-45	35.9
WP_012332636.1\|3106417_3106816_-	response regulator	NA	NA	NA	NA
WP_012330561.1\|3107218_3108619_-\|transposase	IS30-like element ISMtsp4 family transposase	W5R8L2	Staphylococcus_phage	1.4e-26	36.0
WP_083784671.1\|3108618_3110280_-	GAF domain-containing protein	NA	NA	NA	NA
WP_012332637.1\|3110540_3110873_-	hypothetical protein	NA	NA	NA	NA
WP_012332638.1\|3110908_3112504_+	response regulator	W8CYM9	Bacillus_phage	7.8e-13	31.3
WP_012332639.1\|3112620_3113007_-	response regulator	W8CYM9	Bacillus_phage	1.1e-08	31.6
WP_012332640.1\|3113003_3115787_-	response regulator	A0A1V0SGX0	Hokovirus	1.6e-37	33.1
WP_150108831.1\|3115830_3116556_-	DUF3365 domain-containing protein	NA	NA	NA	NA
WP_050777484.1\|3116891_3117212_+	hypothetical protein	NA	NA	NA	NA
WP_012332642.1\|3117415_3118927_+	FAD-dependent tricarballylate dehydrogenase TcuA	A0A2P0ZL82	Lactobacillus_phage	2.4e-24	26.0
3119243:3119302	attL	NA	NA	NA	NA
WP_012332643.1\|3119431_3120448_+\|integrase	site-specific integrase	A0A1S6L1B6	Ralstonia_phage	5.4e-60	42.0
WP_150108648.1\|3120885_3121218_-	hypothetical protein	NA	NA	NA	NA
WP_012332644.1\|3121238_3122204_-	transporter	NA	NA	NA	NA
WP_012331157.1\|3123658_3124768_+\|transposase	IS110-like element ISMtsp6 family transposase	NA	NA	NA	NA
3137680:3137763	attR	NA	NA	NA	NA

DBSCAN-SWA_3

3659706 : 3739892

Bacillus_phage(37.5%)

holin,integrase,transposase

attL 3678582:3678598|attR 3735593:3735609

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_012333109.1\|3659706_3661350_-\|holin	choline dehydrogenase	A0A1V0S9J5	Catovirus	1.4e-54	30.3
WP_168169196.1\|3661697_3662675_-	glycosyltransferase family 2 protein	NA	NA	NA	NA
WP_012333111.1\|3662962_3663964_-	polysaccharide deacetylase family protein	NA	NA	NA	NA
WP_012333112.1\|3663974_3665609_-	glycosyltransferase	NA	NA	NA	NA
WP_012333113.1\|3665931_3667695_+	ABC transporter ATP-binding protein	W8CYL7	Bacillus_phage	4.5e-38	28.1
WP_150108671.1\|3668852_3669233_+	hypothetical protein	NA	NA	NA	NA
WP_012333114.1\|3669722_3670811_-	HlyD family efflux transporter periplasmic adaptor subunit	NA	NA	NA	NA
WP_012333115.1\|3670826_3671951_-	UDP-N-acetylglucosamine 2-epimerase (non-hydrolyzing)	A0A1V0SAG5	Catovirus	1.8e-19	27.7
WP_012333116.1\|3671973_3673302_-	glycosyl transferase family protein	NA	NA	NA	NA
WP_012333117.1\|3674177_3675263_+	chemotaxis sensory transducer	NA	NA	NA	NA
WP_012333119.1\|3675687_3675918_+	hypothetical protein	NA	NA	NA	NA
WP_036270303.1\|3676088_3676652_+	LuxR family transcriptional regulator	NA	NA	NA	NA
WP_043701291.1\|3677350_3679096_+	type I secretion system permease/ATPase	W8CYL7	Bacillus_phage	1.4e-18	28.3
3678582:3678598	attL	NA	NA	NA	NA
WP_012333122.1\|3679095_3680439_+	HlyD family type I secretion periplasmic adaptor subunit	NA	NA	NA	NA
WP_012333123.1\|3680494_3686974_+	structural toxin protein RtxA	NA	NA	NA	NA
WP_083784688.1\|3687462_3687675_-	hypothetical protein	NA	NA	NA	NA
WP_012333124.1\|3689072_3691994_-	response regulator	A0A1V0SGX0	Hokovirus	6.8e-55	34.5
WP_150108672.1\|3692390_3692585_-	hypothetical protein	NA	NA	NA	NA
WP_150108842.1\|3692652_3692934_+	hypothetical protein	NA	NA	NA	NA
WP_012333126.1\|3693417_3694149_-	carbonic anhydrase	NA	NA	NA	NA
WP_043701294.1\|3694389_3695610_-	HNH endonuclease	NA	NA	NA	NA
WP_150108673.1\|3696031_3696313_-	hypothetical protein	NA	NA	NA	NA
WP_012333131.1\|3696447_3696681_+	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_168169160.1\|3698514_3698982_+	hypothetical protein	NA	NA	NA	NA
WP_012333133.1\|3699775_3710095_+	outer membrane adhesin-like protein	NA	NA	NA	NA
WP_012333134.1\|3710449_3710839_+	hypothetical protein	NA	NA	NA	NA
WP_012333135.1\|3711481_3711637_-	Flp family type IVb pilin	NA	NA	NA	NA
WP_150108674.1\|3712329_3713541_-	hypothetical protein	NA	NA	NA	NA
WP_150108675.1\|3714017_3714197_+	hypothetical protein	NA	NA	NA	NA
WP_012333137.1\|3714497_3714809_-	hypothetical protein	NA	NA	NA	NA
WP_085984467.1\|3715229_3716371_-\|transposase	IS3 family transposase	S5WIU1	Leptospira_phage	1.7e-30	32.3
WP_085984460.1\|3717162_3717387_-	hypothetical protein	NA	NA	NA	NA
WP_012331757.1\|3717730_3718006_-	hypothetical protein	NA	NA	NA	NA
WP_012333142.1\|3718685_3719186_-	DUF2165 domain-containing protein	NA	NA	NA	NA
WP_012333143.1\|3719604_3719832_-	hypothetical protein	NA	NA	NA	NA
WP_012333144.1\|3721661_3722153_-	MucR family transcriptional regulator	NA	NA	NA	NA
WP_012333145.1\|3722689_3723394_+	response regulator transcription factor	NA	NA	NA	NA
WP_012333146.1\|3723755_3724520_-	CDP-diacylglycerol diphosphatase	NA	NA	NA	NA
WP_012333148.1\|3724808_3725078_-	hypothetical protein	NA	NA	NA	NA
WP_150108676.1\|3725074_3725425_-	hypothetical protein	NA	NA	NA	NA
WP_012333150.1\|3725522_3725837_-	SH3 domain-containing protein	NA	NA	NA	NA
WP_018260331.1\|3725881_3726118_-	hypothetical protein	NA	NA	NA	NA
WP_012333152.1\|3726360_3726636_-	hypothetical protein	NA	NA	NA	NA
WP_012333153.1\|3726639_3727275_-	ParA family protein	NA	NA	NA	NA
WP_012333154.1\|3727536_3727758_+	hypothetical protein	NA	NA	NA	NA
WP_012333155.1\|3727870_3728104_+	hypothetical protein	NA	NA	NA	NA
WP_043702460.1\|3728211_3729042_+\|integrase	integrase	NA	NA	NA	NA
WP_012333157.1\|3729041_3729317_+	hypothetical protein	NA	NA	NA	NA
WP_012333158.1\|3729387_3729879_-	DUF992 domain-containing protein	NA	NA	NA	NA
WP_012333159.1\|3730846_3731155_+	integration host factor subunit beta	A7KV42	Bacillus_phage	8.5e-09	40.7
WP_012333160.1\|3731283_3731535_+	hypothetical protein	NA	NA	NA	NA
WP_012333161.1\|3731842_3732805_+\|transposase	IS481-like element ISMtsp15 family transposase	NA	NA	NA	NA
WP_012333162.1\|3733935_3734364_+	two pore domain potassium channel family protein	NA	NA	NA	NA
WP_012330561.1\|3734541_3735942_+\|transposase	IS30-like element ISMtsp4 family transposase	W5R8L2	Staphylococcus_phage	1.4e-26	36.0
3735593:3735609	attR	NA	NA	NA	NA
WP_012333163.1\|3736062_3737175_+	PQQ-dependent sugar dehydrogenase	NA	NA	NA	NA
WP_012333164.1\|3737555_3738401_+	hypothetical protein	NA	NA	NA	NA
WP_012333165.1\|3738926_3739892_+\|transposase	IS481-like element ISMtsp16 family transposase	NA	NA	NA	NA

DBSCAN-SWA_4

4434163 : 4469928

Staphylococcus_phage(50.0%)

transposase,integrase

attL 4428547:4428562|attR 4446360:4446375

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
4428547:4428562	attL	NA	NA	NA	NA
WP_150108856.1\|4434163_4435327_-\|integrase	integrase arm-type DNA-binding domain-containing protein	A0A077KET4	Ralstonia_phage	2.3e-91	49.7
WP_150108857.1\|4436673_4438431_+	hypothetical protein	NA	NA	NA	NA
WP_150108858.1\|4438560_4440111_-	hypothetical protein	NA	NA	NA	NA
WP_012333747.1\|4440412_4442020_-	glycosyltransferase	NA	NA	NA	NA
WP_012333748.1\|4442557_4444117_+	glycosyltransferase	NA	NA	NA	NA
WP_012333749.1\|4444155_4445721_+	hypothetical protein	NA	NA	NA	NA
WP_012333750.1\|4445717_4446893_+	glycosyltransferase	NA	NA	NA	NA
4446360:4446375	attR	NA	NA	NA	NA
WP_012333751.1\|4446855_4448226_+	hypothetical protein	NA	NA	NA	NA
WP_012333752.1\|4448727_4449327_-	hypothetical protein	NA	NA	NA	NA
WP_012333753.1\|4450311_4451289_+	glycosyltransferase	NA	NA	NA	NA
WP_012333755.1\|4452679_4453132_+	hypothetical protein	NA	NA	NA	NA
WP_012333756.1\|4453189_4453681_+	hypothetical protein	NA	NA	NA	NA
WP_012333757.1\|4453730_4454234_+	hypothetical protein	NA	NA	NA	NA
WP_012333758.1\|4454237_4455170_+	glycosyltransferase family 2 protein	NA	NA	NA	NA
WP_012333759.1\|4455166_4457167_+	glycosyltransferase	NA	NA	NA	NA
WP_012333760.1\|4457563_4457794_+	hypothetical protein	NA	NA	NA	NA
WP_150108704.1\|4457810_4458038_-\|transposase	transposase domain-containing protein	NA	NA	NA	NA
WP_012333762.1\|4458121_4458769_-	hypothetical protein	NA	NA	NA	NA
WP_012333763.1\|4459029_4459251_+	hypothetical protein	NA	NA	NA	NA
WP_012331380.1\|4459611_4460610_+\|transposase	IS110-like element ISMtsp7 family transposase	NA	NA	NA	NA
WP_012330561.1\|4460995_4462396_+\|transposase	IS30-like element ISMtsp4 family transposase	W5R8L2	Staphylococcus_phage	1.4e-26	36.0
WP_083784708.1\|4462295_4462979_-\|transposase	IS3 family transposase	U5P429	Shigella_phage	3.9e-22	37.9
WP_157182184.1\|4462975_4463266_-	hypothetical protein	NA	NA	NA	NA
WP_043702545.1\|4464077_4465436_-	FAD-binding monooxygenase	NA	NA	NA	NA
WP_012333767.1\|4466849_4467374_+	hypothetical protein	NA	NA	NA	NA
WP_012330561.1\|4468527_4469928_-\|transposase	IS30-like element ISMtsp4 family transposase	W5R8L2	Staphylococcus_phage	1.4e-26	36.0

DBSCAN-SWA_5

4571401 : 4610034

Aurantimonas_phage(14.29%)

transposase,head,portal,tail,capsid,plate,terminase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_012333874.1\|4571401_4571635_-\|tail	tail X family protein	NA	NA	NA	NA
WP_012333875.1\|4571639_4572065_-\|tail	phage tail protein	NA	NA	NA	NA
WP_012333876.1\|4572086_4576331_-\|tail	phage tail tape measure protein	NA	NA	NA	NA
WP_012333877.1\|4576437_4576986_-\|tail	phage tail assembly protein	NA	NA	NA	NA
WP_012333878.1\|4577041_4577569_-\|tail	tail tube protein	NA	NA	NA	NA
WP_012333879.1\|4577636_4578923_-	hypothetical protein	E5FFG9	Burkholderia_phage	4.1e-20	27.4
WP_012333880.1\|4579006_4579519_-	hypothetical protein	NA	NA	NA	NA
WP_012333881.1\|4579555_4580326_-	hypothetical protein	NA	NA	NA	NA
WP_012333882.1\|4580344_4580908_-\|tail	tail fiber protein	A2I2X8	Vibrio_virus	1.2e-08	32.7
WP_012333883.1\|4580900_4581569_-\|tail	phage tail protein I	A0A193GYD1	Enterobacter_phage	5.9e-15	39.7
WP_012333884.1\|4581561_4582557_-\|plate	baseplate J protein	A0A088FQL4	Escherichia_phage	3.5e-27	36.6
WP_012333885.1\|4582580_4583000_-	hypothetical protein	NA	NA	NA	NA
WP_012333886.1\|4583003_4583333_-	hypothetical protein	NA	NA	NA	NA
WP_063826007.1\|4583350_4583929_-\|plate	baseplate assembly protein	A0A219VHA3	Ochrobactrum_phage	2.3e-07	28.2
WP_012333888.1\|4583925_4584720_-	hypothetical protein	NA	NA	NA	NA
WP_012333889.1\|4584716_4585133_-	hypothetical protein	NA	NA	NA	NA
WP_012333890.1\|4585144_4586170_-\|capsid	major capsid protein	A0A0A8ILA9	Aurantimonas_phage	1.1e-44	34.8
WP_012333891.1\|4586290_4586962_-\|head	head decoration protein	NA	NA	NA	NA
WP_012333892.1\|4587004_4588450_-	S49 family peptidase	V5Q836	Xylella_phage	2.4e-45	39.1
WP_012333893.1\|4588462_4588714_-	hypothetical protein	NA	NA	NA	NA
WP_150108862.1\|4588716_4590222_-\|portal	phage portal protein	NA	NA	NA	NA
WP_150108863.1\|4590324_4592331_-\|terminase	terminase	A0A2H4JG09	uncultured_Caudovirales_phage	3.2e-96	37.8
WP_012333896.1\|4592466_4592913_-	hypothetical protein	NA	NA	NA	NA
WP_012333897.1\|4593174_4593732_-	protein tyrosine phosphatase-like protein	NA	NA	NA	NA
WP_168169169.1\|4593728_4593881_-	hypothetical protein	NA	NA	NA	NA
WP_012333899.1\|4593977_4594388_-	hypothetical protein	NA	NA	NA	NA
WP_012333900.1\|4594384_4594921_-	DUF2493 domain-containing protein	A0A291L9X7	Bordetella_phage	2.6e-21	51.8
WP_012333902.1\|4595057_4595462_-	hypothetical protein	A0A0F6R7L8	Sinorhizobium_phage	2.7e-23	50.4
WP_012333903.1\|4595464_4596007_-	hypothetical protein	A0A0A8IL87	Aurantimonas_phage	9.3e-27	43.0
WP_012333904.1\|4596011_4596257_-	hypothetical protein	NA	NA	NA	NA
WP_018261519.1\|4596253_4596493_-	hypothetical protein	NA	NA	NA	NA
WP_012333906.1\|4596489_4596969_-	N-acetyltransferase	NA	NA	NA	NA
WP_012333907.1\|4596965_4597247_-	hypothetical protein	NA	NA	NA	NA
WP_012333909.1\|4597825_4598104_-	hypothetical protein	NA	NA	NA	NA
WP_012333910.1\|4598361_4598625_-	hypothetical protein	NA	NA	NA	NA
WP_085984469.1\|4599586_4600530_-\|transposase	IS630 family transposase	A0A2P0VP61	Tetraselmis_virus	3.6e-10	24.8
WP_150108709.1\|4600709_4601426_-	hypothetical protein	NA	NA	NA	NA
WP_085984499.1\|4601957_4602797_+\|transposase	IS5 family transposase	A0A0N9SHJ4	Paenibacillus_phage	3.0e-24	46.5
WP_012331380.1\|4604074_4605073_-\|transposase	IS110-like element ISMtsp7 family transposase	NA	NA	NA	NA
WP_012333913.1\|4606392_4607499_+	LacI family transcriptional regulator	NA	NA	NA	NA
WP_043702575.1\|4607723_4608839_+\|transposase	IS256 family transposase	A0A220NQR7	Corynebacterium_phage	4.5e-76	47.0
WP_150108864.1\|4608816_4610034_-\|transposase	IS110 family transposase	NA	NA	NA	NA

DBSCAN-SWA_6

4913605 : 4920567

uncultured_Mediterranean_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_012334189.1\|4913605_4914106_+	pantetheine-phosphate adenylyltransferase	A0A1B1IVQ3	uncultured_Mediterranean_phage	1.6e-20	31.3
WP_012334190.1\|4914207_4914747_+	peptidylprolyl isomerase	A0A1B1IVS0	uncultured_Mediterranean_phage	2.9e-36	50.9
WP_012334191.1\|4914736_4915222_+	hypothetical protein	NA	NA	NA	NA
WP_012334192.1\|4915214_4915676_+	peptidylprolyl isomerase	A0A1B1IVS0	uncultured_Mediterranean_phage	3.1e-39	55.0
WP_012334193.1\|4915801_4916470_-	LON peptidase substrate-binding domain-containing protein	NA	NA	NA	NA
WP_012334194.1\|4916536_4917445_-	thioredoxin	A0A1J0GW78	Streptomyces_phage	6.2e-15	37.7
WP_012334195.1\|4917685_4919443_+	ABC transporter ATP-binding protein	W8CYL7	Bacillus_phage	4.2e-28	42.2
WP_012334196.1\|4919583_4920567_+	cysteine synthase A	A0A1X9I5F1	Streptococcus_phage	2.4e-81	52.3

DBSCAN-SWA_7

6070795 : 6139187

uncultured_virus(22.22%)

transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_012290058.1\|6070795_6072079_-\|transposase	IS21-like element ISMtsp8 family transposase	A0A2L1IVA1	Escherichia_phage	1.6e-45	35.9
WP_085984471.1\|6072157_6072400_-	hypothetical protein	NA	NA	NA	NA
WP_012335232.1\|6072503_6073292_-	SDR family oxidoreductase	NA	NA	NA	NA
WP_012335233.1\|6073341_6074694_-	MFS transporter	NA	NA	NA	NA
WP_083784819.1\|6076206_6077286_+	AraC family transcriptional regulator	NA	NA	NA	NA
WP_168169191.1\|6077712_6078057_+	hypothetical protein	NA	NA	NA	NA
WP_083784790.1\|6078291_6078402_+	ArsR family transcriptional regulator	NA	NA	NA	NA
WP_012330759.1\|6078459_6079029_-	DNA-3-methyladenine glycosylase	NA	NA	NA	NA
WP_168169173.1\|6079517_6080612_+	hypothetical protein	NA	NA	NA	NA
WP_012335237.1\|6080668_6080941_+	DUF2312 domain-containing protein	B0VK10	Azospirillum_phage	1.5e-12	48.7
WP_012335238.1\|6080977_6083212_-	ATP-dependent RecD-like DNA helicase	U5J9B0	Bacillus_phage	1.9e-57	27.5
WP_012335239.1\|6085395_6085821_+	cupin domain-containing protein	NA	NA	NA	NA
WP_012332367.1\|6086851_6087865_-\|transposase	IS110-like element ISMtsp9 family transposase	Q75QL1	Wolbachia_phage	7.6e-30	36.9
WP_012335242.1\|6090346_6090772_+	PAS sensor domain-containing protein	NA	NA	NA	NA
WP_012335243.1\|6092220_6092430_+	hypothetical protein	NA	NA	NA	NA
WP_012335244.1\|6095508_6095694_-	hypothetical protein	NA	NA	NA	NA
WP_012335245.1\|6095774_6096986_+	depolymerase	NA	NA	NA	NA
WP_012335246.1\|6097217_6098057_-	hypothetical protein	NA	NA	NA	NA
WP_150108736.1\|6098221_6098527_+	hypothetical protein	NA	NA	NA	NA
WP_012335248.1\|6099536_6100301_-	hypothetical protein	NA	NA	NA	NA
WP_012335249.1\|6100597_6101620_-	lytic transglycosylase domain-containing protein	A0A0A0P1R1	Enterobacteria_phage	2.3e-10	35.6
WP_012335251.1\|6102582_6103014_-	MucR family transcriptional regulator	NA	NA	NA	NA
WP_012335252.1\|6103253_6103724_-	MucR family transcriptional regulator	NA	NA	NA	NA
WP_012335254.1\|6104766_6105078_+	hypothetical protein	NA	NA	NA	NA
WP_168169174.1\|6105086_6105251_-	hypothetical protein	NA	NA	NA	NA
WP_050777587.1\|6105250_6106252_-	transporter	NA	NA	NA	NA
WP_043701673.1\|6106486_6106738_-	hypothetical protein	NA	NA	NA	NA
WP_043701676.1\|6107230_6107440_-	hypothetical protein	NA	NA	NA	NA
WP_012335258.1\|6107966_6109487_-	sodium/hydrogen exchanger	NA	NA	NA	NA
WP_012335259.1\|6109580_6109898_+\|transposase	IS6 family transposase	A0A1X9I6E7	Streptococcus_phage	1.8e-09	36.0
WP_168169175.1\|6109924_6110662_-	GntR family transcriptional regulator	NA	NA	NA	NA
WP_012335261.1\|6110789_6111980_+	ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_043701679.1\|6113533_6114775_-	ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_012335263.1\|6114801_6115779_-	hypothetical protein	NA	NA	NA	NA
WP_012335264.1\|6116429_6116960_-	hypothetical protein	NA	NA	NA	NA
WP_012335265.1\|6117015_6118800_-	Rieske 2Fe-2S domain-containing protein	NA	NA	NA	NA
WP_012335266.1\|6120581_6122222_-	chaperonin GroEL	A0A240F779	uncultured_virus	4.3e-168	57.8
WP_012335267.1\|6122311_6122599_-	co-chaperone GroES	A0A221S4G8	uncultured_virus	1.3e-22	59.6
WP_012335268.1\|6123548_6125309_+	PAS domain S-box protein	NA	NA	NA	NA
WP_012335269.1\|6125377_6125752_-	histidine kinase	NA	NA	NA	NA
WP_012335270.1\|6125901_6127074_-	GAF domain-containing protein	NA	NA	NA	NA
WP_012335271.1\|6127719_6129090_-	sn-glycerol-3-phosphate ABC transporter substrate-binding protein UgpB	NA	NA	NA	NA
WP_012335272.1\|6129133_6131455_-	HAMP domain-containing protein	NA	NA	NA	NA
WP_012335273.1\|6132309_6133431_-\|transposase	IS630 family transposase	NA	NA	NA	NA
WP_150108738.1\|6134348_6134774_+	hypothetical protein	NA	NA	NA	NA
WP_012330561.1\|6134911_6136312_+\|transposase	IS30-like element ISMtsp4 family transposase	W5R8L2	Staphylococcus_phage	1.4e-26	36.0
WP_012335274.1\|6136434_6137955_-	HAMP domain-containing histidine kinase	NA	NA	NA	NA
WP_012335275.1\|6138164_6139187_+\|transposase	IS110-like element ISMtsp17 family transposase	NA	NA	NA	NA

DBSCAN-SWA_8

6411629 : 6422681

Escherichia_phage(28.57%)

tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_012335499.1\|6411629_6414290_+\|tRNA	alanine--tRNA ligase	A0A1V0SK38	Klosneuvirus	1.8e-83	37.4
WP_012335500.1\|6414435_6414990_+	dTDP-4-dehydrorhamnose 3,5-epimerase	A0A1D7XFA9	Escherichia_phage	2.1e-26	39.5
WP_012335501.1\|6415014_6416067_+	dTDP-glucose 4,6-dehydratase	I7HTA3	Enterobacteria_phage	2.2e-88	47.3
WP_012335502.1\|6416074_6416968_+	dTDP-4-dehydrorhamnose reductase	A0A291LA50	Escherichia_phage	2.9e-17	32.2
WP_018263793.1\|6416979_6417864_+	glucose-1-phosphate thymidylyltransferase RfbA	I7I009	Enterobacteria_phage	1.3e-94	55.9
WP_018263792.1\|6417906_6419181_-\|tRNA	tyrosine--tRNA ligase	K4F5T3	Cronobacter_phage	1.7e-50	33.2
WP_012335505.1\|6419342_6420470_+	anhydro-N-acetylmuramic acid kinase	NA	NA	NA	NA
WP_012335506.1\|6420466_6421060_+	DUF3578 domain-containing protein	NA	NA	NA	NA
WP_012335507.1\|6421307_6422681_+	N-acetylmuramoyl-L-alanine amidase	Q5YA51	Bacillus_phage	3.9e-13	30.3

DBSCAN-SWA_9

6547031 : 6556312

Rhizobium_phage(50.0%)

terminase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_012335614.1\|6547031_6548402_+\|terminase	phage terminase large subunit	H9C0U8	Aeromonas_phage	7.7e-94	45.1
WP_012335615.1\|6548401_6549664_+	DUF1073 domain-containing protein	L7TRA1	Rhizobium_phage	1.3e-74	41.0
WP_012335616.1\|6550022_6550934_+	DUF2213 domain-containing protein	L7TMD6	Rhizobium_phage	6.2e-39	49.4
WP_012335617.1\|6550933_6551371_+	DUF2190 family protein	A0A2R3UAC1	Siphoviridae_environmental_samples	2.3e-15	41.9
WP_012335618.1\|6551382_6552327_+	DUF2184 domain-containing protein	L7TMZ5	Rhizobium_phage	7.2e-75	48.9
WP_012335619.1\|6552331_6552541_+	hypothetical protein	NA	NA	NA	NA
WP_012335620.1\|6552542_6552908_+	DUF4054 domain-containing protein	NA	NA	NA	NA
WP_012335621.1\|6552907_6553228_+	hypothetical protein	NA	NA	NA	NA
WP_012335622.1\|6553227_6553521_+	hypothetical protein	NA	NA	NA	NA
WP_012335623.1\|6553522_6553936_+	DUF3168 domain-containing protein	NA	NA	NA	NA
WP_012335624.1\|6554002_6554470_+	hypothetical protein	NA	NA	NA	NA
WP_012335625.1\|6554478_6555060_+	gene transfer agent family protein	NA	NA	NA	NA
WP_012335626.1\|6555043_6556312_+	hypothetical protein	A0A2D2W291	Sinorhizobium_phage	2.1e-05	32.4

DBSCAN-SWA_10

7398115 : 7430781

Erythrobacter_phage(18.18%)

transposase,integrase

attL 7397892:7397948|attR 7430798:7430854

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
7397892:7397948	attL	NA	NA	NA	NA
WP_043701891.1\|7398115_7399369_+\|integrase	site-specific integrase	A0A0R6PIF4	Moraxella_phage	5.0e-23	27.3
WP_150108781.1\|7399365_7399929_+	hypothetical protein	NA	NA	NA	NA
WP_012336349.1\|7400035_7400251_+	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_012336350.1\|7400254_7400707_+	hypothetical protein	NA	NA	NA	NA
WP_083784824.1\|7400954_7403162_+	AAA family ATPase	A0A1U9ZA69	Proteus_phage	3.5e-11	38.5
WP_012336353.1\|7403687_7404023_+	hypothetical protein	NA	NA	NA	NA
WP_012336354.1\|7404130_7404565_+	hypothetical protein	NA	NA	NA	NA
WP_012336355.1\|7404620_7405448_-	hypothetical protein	NA	NA	NA	NA
WP_012336356.1\|7405449_7405713_-	hypothetical protein	NA	NA	NA	NA
WP_012330561.1\|7406351_7407752_-\|transposase	IS30-like element ISMtsp4 family transposase	W5R8L2	Staphylococcus_phage	1.4e-26	36.0
WP_012336358.1\|7408413_7409448_-\|transposase	ISL3 family transposase	NA	NA	NA	NA
WP_012336359.1\|7409890_7410463_+	class I SAM-dependent methyltransferase	A0A1V0S9B9	Catovirus	1.7e-26	35.3
WP_012336360.1\|7410735_7411488_+\|transposase	IS6 family transposase	A0A077SL39	Escherichia_phage	5.8e-43	46.2
WP_012336361.1\|7411606_7412050_-	CHRD domain-containing protein	NA	NA	NA	NA
WP_012336362.1\|7412101_7412518_-	hypothetical protein	NA	NA	NA	NA
WP_012336363.1\|7412783_7413278_-	MucR family transcriptional regulator	A0A1P8VVG0	Erythrobacter_phage	2.5e-26	51.6
WP_012336366.1\|7414700_7415132_-	MucR family transcriptional regulator	A0A1P8VVG0	Erythrobacter_phage	5.9e-24	53.3
WP_085984506.1\|7415372_7415786_-	MucR family transcriptional regulator	NA	NA	NA	NA
WP_168169122.1\|7416005_7416323_+	hypothetical protein	NA	NA	NA	NA
WP_168169183.1\|7416458_7416977_-	TSUP family transporter	NA	NA	NA	NA
WP_043701906.1\|7416924_7417254_-	hypothetical protein	NA	NA	NA	NA
WP_150108782.1\|7417574_7418060_-	hypothetical protein	NA	NA	NA	NA
WP_150108902.1\|7418604_7419585_+	hypothetical protein	NA	NA	NA	NA
WP_012336370.1\|7419771_7420377_+	recombinase family protein	A0A1S6L009	Salmonella_phage	4.5e-46	54.1
WP_012336371.1\|7420862_7421150_+	hypothetical protein	NA	NA	NA	NA
WP_012336372.1\|7421349_7422273_+	formylglycine-generating enzyme family protein	NA	NA	NA	NA
WP_012336373.1\|7422269_7423979_+	arylsulfatase	A0A2P0VMN7	Tetraselmis_virus	1.5e-54	33.8
WP_012336374.1\|7424329_7425343_+	transporter	NA	NA	NA	NA
WP_012336375.1\|7425381_7426830_-	DUF1254 domain-containing protein	M1IA53	Paramecium_bursaria_Chlorella_virus	1.1e-53	33.0
WP_083784772.1\|7427689_7427911_+	hypothetical protein	NA	NA	NA	NA
WP_050777534.1\|7427981_7428236_+	hypothetical protein	NA	NA	NA	NA
WP_012330183.1\|7429015_7430215_+\|transposase	IS256-like element ISMtsp13 family transposase	A0A220NQR7	Corynebacterium_phage	9.1e-91	47.4
WP_168169184.1\|7430397_7430781_-\|transposase	transposase	NA	NA	NA	NA
7430798:7430854	attR	NA	NA	NA	NA

DBSCAN-SWA_11

7557844 : 7608665

Rhizobium_phage(16.67%)

transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_012336480.1\|7557844_7559053_+\|transposase	IS701-like element ISMtsp19 family transposase	NA	NA	NA	NA
WP_012336481.1\|7559533_7560196_+	DUF1345 domain-containing protein	NA	NA	NA	NA
WP_012336482.1\|7560538_7561231_-	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_043702834.1\|7562206_7562674_+	ATPase	NA	NA	NA	NA
WP_012336485.1\|7562679_7563312_+	deaminase reductase	NA	NA	NA	NA
WP_012336486.1\|7563515_7563899_+	glyoxalase/bleomycin resistance/dioxygenase family protein	NA	NA	NA	NA
WP_012336487.1\|7564519_7565692_+	hypothetical protein	NA	NA	NA	NA
WP_012336488.1\|7566255_7566495_+	hypothetical protein	NA	NA	NA	NA
WP_012336489.1\|7567382_7568756_-	MFS transporter	NA	NA	NA	NA
WP_012336490.1\|7568954_7570859_-	phenol 2-monooxygenase	NA	NA	NA	NA
WP_012336491.1\|7571217_7571697_+	MarR family transcriptional regulator	NA	NA	NA	NA
WP_043701921.1\|7573272_7573470_+	hypothetical protein	NA	NA	NA	NA
WP_043702837.1\|7574467_7574725_+	hypothetical protein	NA	NA	NA	NA
WP_168169185.1\|7575542_7575692_-	hypothetical protein	NA	NA	NA	NA
WP_012336497.1\|7576163_7576400_+	hypothetical protein	NA	NA	NA	NA
WP_083784778.1\|7576775_7577060_-	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_085984477.1\|7577075_7578169_-\|transposase	IS630 family transposase	NA	NA	NA	NA
WP_012336500.1\|7578976_7579660_+	sigma-70 family RNA polymerase sigma factor	A0A076YQ50	Rhizobium_phage	3.6e-07	29.0
WP_012336501.1\|7579654_7580287_-	recombinase family protein	NA	NA	NA	NA
WP_012336502.1\|7580938_7581154_+	hypothetical protein	NA	NA	NA	NA
WP_012336504.1\|7583368_7583596_+	hypothetical protein	NA	NA	NA	NA
WP_168169186.1\|7585415_7585733_-	hypothetical protein	NA	NA	NA	NA
WP_012336507.1\|7585984_7586437_+	hypothetical protein	NA	NA	NA	NA
WP_012336508.1\|7587075_7587255_-	hypothetical protein	NA	NA	NA	NA
WP_012336509.1\|7587500_7587761_+	hypothetical protein	NA	NA	NA	NA
WP_150108785.1\|7587902_7588127_+	hypothetical protein	NA	NA	NA	NA
WP_012336511.1\|7588263_7588758_+	MucR family transcriptional regulator	NA	NA	NA	NA
WP_012336512.1\|7588971_7589424_-	hypothetical protein	NA	NA	NA	NA
WP_168169187.1\|7589566_7590955_+	PAS domain-containing protein	NA	NA	NA	NA
WP_012336514.1\|7591400_7592876_-	methyl-accepting chemotaxis protein	A0A2H4J162	uncultured_Caudovirales_phage	1.5e-05	58.9
WP_012336515.1\|7593344_7594145_-	hypothetical protein	NA	NA	NA	NA
WP_085984480.1\|7594366_7595310_-\|transposase	IS630 family transposase	A0A2P0VP61	Tetraselmis_virus	7.3e-11	24.8
WP_168169188.1\|7595532_7595694_+	hypothetical protein	NA	NA	NA	NA
WP_043701932.1\|7596171_7596426_+	hypothetical protein	NA	NA	NA	NA
WP_012336520.1\|7596894_7597083_-	hypothetical protein	NA	NA	NA	NA
WP_168169189.1\|7597445_7597901_+	hypothetical protein	NA	NA	NA	NA
WP_012336521.1\|7598523_7599360_+\|transposase	IS5-like element ISMtsp20 family transposase	NA	NA	NA	NA
WP_150108787.1\|7600175_7601006_+	hypothetical protein	NA	NA	NA	NA
WP_012336523.1\|7601459_7602449_-	hypothetical protein	NA	NA	NA	NA
WP_012336525.1\|7604394_7605795_+\|transposase	IS30-like element ISMtsp4 family transposase	W5R8L2	Staphylococcus_phage	1.4e-26	36.0
WP_012290057.1\|7606509_7607385_-	ATP-binding protein	U5N3V8	Enterobacteria_phage	2.1e-52	45.6
WP_012290058.1\|7607381_7608665_-\|transposase	IS21-like element ISMtsp8 family transposase	A0A2L1IVA1	Escherichia_phage	1.6e-45	35.9

Anti-CRISPR protein detection

Acr_ID: NC_010511.1|WP_018260759.1|3080780_3081071_+|hypothetical-protein

Click the colored protein region to show detailed information

Acr_ID: NC_010511.1|WP_150108646.1|3083097_3083352_-|hypothetical-protein

Click the colored protein region to show detailed information

Acr_ID: NC_010511.1|WP_012332637.1|3110540_3110873_-|hypothetical-protein

Click the colored protein region to show detailed information

Acr_ID: NC_010511.1|WP_150108673.1|3696031_3696313_-|hypothetical-protein

Click the colored protein region to show detailed information

Acr_ID: NC_010511.1|WP_012333143.1|3719604_3719832_-|hypothetical-protein

Click the colored protein region to show detailed information

Acr_ID: NC_010511.1|WP_012333160.1|3731283_3731535_+|hypothetical-protein

Click the colored protein region to show detailed information

Acr ID

Acr position

Acr size

Homology with known anti

Neighbor HTH/AcRanker

Neighbor Aca

In prophage

Protospacer in prophage

NC_010511.1|WP_018260759.1|3080780_3081071_+|hypothetical-protein

3080780_3081071_+

96 aa aa

3067002-3124768

yes

CRISPR ID	CRISPR type	Spacer info	Spacer location	Spacer length	Protospacer location	Mismatch
NC_010511_25	Orphan	25.1\|4213563\|42\|NC_010511\|CRISPRCasFinder	4213563-4213604	42	3070289-3070248	2

1. spacer 25.1|4213563|42|NC_010511|CRISPRCasFinder matches to NC_010511 position: 3070289-3070248, mismatch: 2

tacccaatccgctcgatcccttcgggatggcggattggggct	CRISPR spacer
tacccaatccgctcgatccctccgggatggcggatttgggct	Protospacer
*********************.************** *****

NC_010511.1|WP_150108646.1|3083097_3083352_-|hypothetical-protein

3083097_3083352_-

84 aa aa

3067002-3124768

yes

CRISPR ID	CRISPR type	Spacer info	Spacer location	Spacer length	Protospacer location	Mismatch
NC_010511_25	Orphan	25.1\|4213563\|42\|NC_010511\|CRISPRCasFinder	4213563-4213604	42	3070289-3070248	2

1. spacer 25.1|4213563|42|NC_010511|CRISPRCasFinder matches to NC_010511 position: 3070289-3070248, mismatch: 2

tacccaatccgctcgatcccttcgggatggcggattggggct	CRISPR spacer
tacccaatccgctcgatccctccgggatggcggatttgggct	Protospacer
*********************.************** *****

NC_010511.1|WP_012332637.1|3110540_3110873_-|hypothetical-protein

3110540_3110873_-

110 aa aa

3067002-3124768

yes

CRISPR ID	CRISPR type	Spacer info	Spacer location	Spacer length	Protospacer location	Mismatch
NC_010511_25	Orphan	25.1\|4213563\|42\|NC_010511\|CRISPRCasFinder	4213563-4213604	42	3070289-3070248	2

1. spacer 25.1|4213563|42|NC_010511|CRISPRCasFinder matches to NC_010511 position: 3070289-3070248, mismatch: 2

tacccaatccgctcgatcccttcgggatggcggattggggct	CRISPR spacer
tacccaatccgctcgatccctccgggatggcggatttgggct	Protospacer
*********************.************** *****

NC_010511.1|WP_150108673.1|3696031_3696313_-|hypothetical-protein

3696031_3696313_-

93 aa aa

3659706-3739892

yes

CRISPR ID	CRISPR type	Spacer info	Spacer location	Spacer length	Protospacer location	Mismatch
NC_010511_29	Orphan	29.1\|4808291\|44\|NC_010511\|CRISPRCasFinder	4808291-4808334	44	3661571-3661528	1

1. spacer 29.1|4808291|44|NC_010511|CRISPRCasFinder matches to NC_010511 position: 3661571-3661528, mismatch: 1

caaatccgccatcccgaagggatcaagcggatttggtatgacac	CRISPR spacer
caaatccgccatcccgaagagatcaagcggatttggtatgacac	Protospacer
*******************.************************

NC_010511.1|WP_012333143.1|3719604_3719832_-|hypothetical-protein

3719604_3719832_-

75 aa aa

3659706-3739892

yes

CRISPR ID	CRISPR type	Spacer info	Spacer location	Spacer length	Protospacer location	Mismatch
NC_010511_29	Orphan	29.1\|4808291\|44\|NC_010511\|CRISPRCasFinder	4808291-4808334	44	3661571-3661528	1

1. spacer 29.1|4808291|44|NC_010511|CRISPRCasFinder matches to NC_010511 position: 3661571-3661528, mismatch: 1

caaatccgccatcccgaagggatcaagcggatttggtatgacac	CRISPR spacer
caaatccgccatcccgaagagatcaagcggatttggtatgacac	Protospacer
*******************.************************

NC_010511.1|WP_012333160.1|3731283_3731535_+|hypothetical-protein

3731283_3731535_+

83 aa aa

3659706-3739892

yes

CRISPR ID	CRISPR type	Spacer info	Spacer location	Spacer length	Protospacer location	Mismatch
NC_010511_29	Orphan	29.1\|4808291\|44\|NC_010511\|CRISPRCasFinder	4808291-4808334	44	3661571-3661528	1

1. spacer 29.1|4808291|44|NC_010511|CRISPRCasFinder matches to NC_010511 position: 3661571-3661528, mismatch: 1

caaatccgccatcccgaagggatcaagcggatttggtatgacac	CRISPR spacer
caaatccgccatcccgaagagatcaagcggatttggtatgacac	Protospacer
*******************.************************

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. NC_010511

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CRISPR-Cas detection and classification

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