CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Target MGE spacer number	Prophage number
NC_011281	Klebsiella variicola plasmid pKP91, complete sequence	0 crisprs	NA	0	1
NC_011282	Klebsiella variicola plasmid pKP187, complete sequence	0 crisprs	csa3	0	1
NC_011283	Klebsiella variicola, complete sequence	3 crisprs	csa3,cas3,DEDDh,DinG,WYL,cas3HD	1	12

Results visualization

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CRISPR-Cas detection and classification

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

3868 : 59631

Bacillus_phage(16.67%)

transposase

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_012539975.1\|3868_5107_+\|transposase	IS110 family transposase	A0A0U3ULR1	Bacillus_phage	8.4e-07	21.9
WP_012539993.1\|5332_6148_+	SDR family oxidoreductase	NA	NA	NA	NA
WP_012540011.1\|6177_6939_+	SDR family NAD(P)-dependent oxidoreductase	Q06VL0	Trichoplusia_ni_ascovirus	1.3e-05	25.7
WP_012540017.1\|6982_8182_+	MFS transporter	NA	NA	NA	NA
WP_012539961.1\|8192_9128_+	GlxA family transcriptional regulator	NA	NA	NA	NA
WP_012539953.1\|10043_10940_-	oxidoreductase	NA	NA	NA	NA
WP_012539974.1\|11016_11901_+	MurR/RpiR family transcriptional regulator	NA	NA	NA	NA
WP_012539940.1\|11900_12758_+	EamA family transporter	NA	NA	NA	NA
WP_000654804.1\|14068_15037_+\|transposase	IS5-like element IS903B family transposase	A0A1B0VFY5	Salmonella_phage	1.0e-185	99.4
WP_012539941.1\|15160_16024_-	HlyD family secretion protein	NA	NA	NA	NA
WP_004899298.1\|16020_16236_-	DUF1656 domain-containing protein	NA	NA	NA	NA
WP_012539943.1\|16225_18265_-	FUSC family protein	NA	NA	NA	NA
WP_012539999.1\|18341_19148_+	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_012540004.1\|19313_20258_-	GlxA family transcriptional regulator	NA	NA	NA	NA
WP_012540027.1\|20359_21049_+	DJ-1/PfpI family protein	NA	NA	NA	NA
WP_012539980.1\|21100_21844_+	SDR family oxidoreductase	Q06VL0	Trichoplusia_ni_ascovirus	5.0e-23	33.2
WP_012539947.1\|23032_23671_+	recombinase family protein	NA	NA	NA	NA
WP_012539995.1\|23854_24325_+	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_012540022.1\|24664_25369_+\|transposase	IS6 family transposase	A0A077SL39	Escherichia_phage	1.2e-122	88.0
WP_012539951.1\|25687_27685_-	transketolase	NA	NA	NA	NA
WP_012539959.1\|27711_28152_-	PTS sugar transporter subunit IIA	NA	NA	NA	NA
WP_012540002.1\|28374_29112_+	GntR family transcriptional regulator	NA	NA	NA	NA
WP_012540007.1\|29172_30204_-	alcohol dehydrogenase catalytic domain-containing protein	A0A0K0KVL7	Prochlorococcus_phage	1.6e-06	22.3
WP_012539970.1\|30247_31729_-	PTS mannitol transporter subunit IICB	NA	NA	NA	NA
WP_123809115.1\|32445_32844_-	hypothetical protein	NA	NA	NA	NA
WP_123809116.1\|33064_34185_-\|transposase	IS3 family transposase	S5WIU1	Leptospira_phage	6.6e-51	42.4
WP_012539992.1\|34838_36248_+\|transposase	ISNCY family transposase	NA	NA	NA	NA
WP_012539976.1\|36291_36810_-	GrpB family protein	A0A2K5B2B6	Erysipelothrix_phage	4.4e-26	38.8
WP_041165526.1\|37084_37606_+	hypothetical protein	NA	NA	NA	NA
WP_012540023.1\|38526_38946_+	ASCH domain-containing protein	NA	NA	NA	NA
WP_032700858.1\|39861_40197_+	TonB family protein	NA	NA	NA	NA
WP_012539969.1\|40221_40764_+	GNAT family N-acetyltransferase	G9BWD5	Planktothrix_phage	7.4e-08	34.2
WP_012540036.1\|41052_41343_+	hypothetical protein	NA	NA	NA	NA
WP_012540018.1\|41378_41681_-	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_012539985.1\|41729_42053_-	type II toxin-antitoxin system RelE/ParE family toxin	NA	NA	NA	NA
WP_170873325.1\|42965_43592_-	peptidase	NA	NA	NA	NA
WP_012539965.1\|44094_45090_+\|transposase	IS110 family transposase	A0A1S7J231	Thermus_phage	2.7e-19	29.2
WP_012540031.1\|45210_46005_-	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_012540016.1\|46092_47283_+	CynX/NimT family MFS transporter	NA	NA	NA	NA
WP_071822081.1\|47797_47983_+	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_012540013.1\|48219_48792_-	flavin reductase	NA	NA	NA	NA
WP_012540014.1\|48886_49402_-	NAD(P)H-dependent oxidoreductase	NA	NA	NA	NA
WP_012539945.1\|49418_50384_-	aldo/keto reductase	NA	NA	NA	NA
WP_041165533.1\|50500_51394_+	LysR family transcriptional regulator	NA	NA	NA	NA
WP_012539936.1\|51590_52478_-	LysR family transcriptional regulator	NA	NA	NA	NA
WP_012540006.1\|52620_54018_+	amidohydrolase family protein	NA	NA	NA	NA
WP_012539997.1\|54032_54506_+	DMT family transporter	NA	NA	NA	NA
WP_012540029.1\|54604_55465_+	SMP-30/gluconolactonase/LRE family protein	NA	NA	NA	NA
WP_012540026.1\|55570_56524_-	aromatic alcohol reductase	NA	NA	NA	NA
WP_032700860.1\|56614_57028_+	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_012539955.1\|57357_58314_+	alpha/beta hydrolase	A0A068F2G2	Mycobacterium_phage	1.9e-14	29.1
WP_012539975.1\|58392_59631_-\|transposase	IS110 family transposase	A0A0U3ULR1	Bacillus_phage	8.4e-07	21.9

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

2. NC_011282

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CRISPR-Cas detection and classification

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

1760 : 60310

uncultured_Caudovirales_phage(26.32%)

transposase,integrase

attL 7330:7344|attR 48595:48609

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_012540205.1\|1760_2897_+\|integrase	tyrosine-type recombinase/integrase	NA	NA	NA	NA
WP_012540152.1\|2962_3280_-	hypothetical protein	NA	NA	NA	NA
WP_012540070.1\|3495_3819_-	hypothetical protein	NA	NA	NA	NA
WP_012540171.1\|3815_4574_-	hypothetical protein	NA	NA	NA	NA
WP_012540153.1\|4570_5530_-	DNA replication protein	NA	NA	NA	NA
WP_041165476.1\|5572_5980_-	hypothetical protein	NA	NA	NA	NA
WP_012540064.1\|5989_6454_-	hypothetical protein	NA	NA	NA	NA
WP_012540189.1\|6501_6744_-	hypothetical protein	NA	NA	NA	NA
7330:7344	attL	NA	NA	NA	NA
WP_123809108.1\|8036_9135_+\|transposase	IS3 family transposase	S5WIU1	Leptospira_phage	1.1e-47	42.4
WP_012540240.1\|10174_11395_+\|transposase	ISL3 family transposase	NA	NA	NA	NA
WP_012540237.1\|12105_13071_-	ParB/RepB/Spo0J family plasmid partition protein	I3WF22	Macacine_betaherpesvirus	9.4e-155	88.8
WP_000523815.1\|13070_14237_-	plasmid-partitioning protein SopA	A0A2I6B2X3	Macacine_betaherpesvirus	1.8e-224	97.7
WP_012540192.1\|14946_15957_+	replication initiation protein	J9Q7H0	Salmonella_phage	7.4e-86	56.4
WP_012540156.1\|16762_17503_-\|integrase	site-specific integrase	I3WFA4	Macacine_betaherpesvirus	2.7e-24	55.3
WP_012540234.1\|21721_22699_-	hypothetical protein	NA	NA	NA	NA
WP_012540046.1\|23082_23379_+	hypothetical protein	A0A0K0VLY7	Klebsiella_phage	1.8e-19	58.0
WP_012540183.1\|25273_26332_+	sensor domain-containing diguanylate cyclase	A0A127AWB9	Bacillus_phage	4.7e-14	32.0
WP_012540197.1\|26686_27379_+	EAL domain-containing protein	NA	NA	NA	NA
WP_004026357.1\|29721_30165_+	DUF2384 domain-containing protein	NA	NA	NA	NA
WP_012540044.1\|30161_30632_+	RES family NAD+ phosphorylase	NA	NA	NA	NA
WP_041165481.1\|30742_31003_-	hypothetical protein	NA	NA	NA	NA
WP_123809109.1\|31701_33070_+\|transposase	IS3 family transposase	A0A2I6AZV9	Macacine_betaherpesvirus	4.1e-79	70.1
WP_012540252.1\|33288_33639_+	As(III)-sensing metalloregulatory transcriptional repressor ArsR	A0A2H4J145	uncultured_Caudovirales_phage	5.3e-23	50.9
WP_012540111.1\|33686_34049_+	arsenite efflux transporter metallochaperone ArsD	NA	NA	NA	NA
WP_012540169.1\|34066_35818_+	arsenite efflux transporter ATPase subunit ArsA	NA	NA	NA	NA
WP_012540054.1\|35865_37155_+	arsenite efflux transporter membrane subunit ArsB	A0A2H4J144	uncultured_Caudovirales_phage	4.6e-173	74.5
WP_012540118.1\|37167_37593_+	glutaredoxin-dependent arsenate reductase	A0A2H4J8T1	uncultured_Caudovirales_phage	1.5e-51	71.4
WP_012540238.1\|37627_38164_-	N-acetyltransferase	NA	NA	NA	NA
WP_012540216.1\|38288_40040_-	arsenical pump-driving ATPase	NA	NA	NA	NA
WP_012540155.1\|40066_40429_-	arsenic metallochaperone ArsD family protein	NA	NA	NA	NA
WP_012540227.1\|40504_41050_-	sigma-70 family RNA polymerase sigma factor	NA	NA	NA	NA
WP_012540184.1\|41058_41772_-	arsenical resistance protein ArsH	A0A2H4J5V6	uncultured_Caudovirales_phage	1.1e-96	73.1
WP_012540250.1\|41773_42097_-	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_012540086.1\|42396_42663_+	DUF1778 domain-containing protein	NA	NA	NA	NA
WP_012540220.1\|42650_43136_+	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_012540069.1\|43840_44218_-	hypothetical protein	NA	NA	NA	NA
WP_012540230.1\|45399_45903_-	hypothetical protein	NA	NA	NA	NA
WP_077251732.1\|46195_46891_+\|integrase	integrase arm-type DNA-binding domain-containing protein	B7SYF8	Stenotrophomonas_phage	4.0e-14	45.6
WP_012540246.1\|46948_47128_+	hypothetical protein	NA	NA	NA	NA
WP_012540217.1\|47285_47630_+	hypothetical protein	A0A2H4JFA4	uncultured_Caudovirales_phage	8.6e-10	37.4
WP_041165485.1\|47514_47997_+	hypothetical protein	Q7M2A8	Enterobacteria_phage	7.3e-15	36.4
WP_012540180.1\|48311_48533_+	hypothetical protein	NA	NA	NA	NA
WP_012540091.1\|48795_50400_+	hypothetical protein	NA	NA	NA	NA
48595:48609	attR	NA	NA	NA	NA
WP_012540151.1\|50734_50911_+	hypothetical protein	NA	NA	NA	NA
WP_012540097.1\|50937_51195_+	hypothetical protein	NA	NA	NA	NA
WP_012540199.1\|51304_51787_+	hypothetical protein	NA	NA	NA	NA
WP_012540082.1\|51783_53646_+	hypothetical protein	A0A2R3UAN6	Myoviridae_environmental_samples	5.1e-16	23.4
WP_041165487.1\|53993_54581_+	hypothetical protein	NA	NA	NA	NA
WP_012540188.1\|55494_56637_-	hypothetical protein	NA	NA	NA	NA
WP_101826062.1\|56680_57130_-	hypothetical protein	A0A0U2JTY1	Escherichia_phage	7.0e-44	55.0
WP_012540204.1\|57539_57887_+	hypothetical protein	NA	NA	NA	NA
WP_012540041.1\|58473_58830_+	hypothetical protein	NA	NA	NA	NA
WP_012540236.1\|58917_59103_-	hypothetical protein	Q6UAT4	Klebsiella_phage	2.2e-20	88.3
WP_123809110.1\|59211_60310_+\|transposase	IS3 family transposase	S5WIU1	Leptospira_phage	1.3e-46	42.0

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

3. NC_011283

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Crispr_ID: NC_011283_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_011283_1

616973-617062

Orphan

Consensus_repeat	Method
GTGCCGAACGGTTCCCTCACCCA	CRISPRCasFinder

1 spacers

The CRISPR arrays of NC_011283_1

>merge|NC_011283|1|616973-617062|CRISPRCasFinder
GTGCCGAACGGTTCCCTCACCCAAAGGGCGAGGGGGAAAGGCGGATCGGCATCGGTATTCAAGGCCTGTGCCGAACGGTTCCCTCTCCCA

>NC_011283|1|1|616973-617062|CRISPRCasFinder
GTGCCGAACGGTTCCCTCACCCA	AAGGGCGAGGGGGAAAGGCGGATCGGCATCGGTATTCAAGGCCT
GTGCCGAACGGTTCCCTCTCCCA

Protein	Signature genes	Signature genes Name	Protein_function
NC_011283.1\|WP_008806562.1\|627303_627858_-\|PadR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|224609
NC_011283.1\|WP_012540501.1\|608660_609161_-\|M48-family-metallopeptidase	unknown	unknown	gnl\|CDD\|224368
NC_011283.1\|WP_012540505.1\|613404_614535_+\|23S-rRNA-(guanine(1835)-N(2))-methyltransferase-RlmG	unknown	unknown	gnl\|CDD\|184963
NC_011283.1\|WP_012540512.1\|625666_627046_-\|putrescine-aminotransferase	unknown	unknown	gnl\|CDD\|183175
NC_011283.1\|WP_012540504.1\|611987_613328_+\|MFS-transporter	unknown	unknown	gnl\|CDD\|236610
NC_011283.1\|WP_012540503.1\|611012_611879_-\|helix-turn-helix-transcriptional-regulator	unknown	unknown	gnl\|CDD\|225117
NC_011283.1\|WP_002917723.1\|625322_625619_+\|(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione-isomerase	unknown	unknown	gnl\|CDD\|182494
NC_011283.1\|WP_012540497.1\|604305_604860_+\|YgjV-family-protein	unknown	unknown	gnl\|CDD\|378474
NC_011283.1\|WP_012540499.1\|606354_607326_-\|TerC-family-protein	unknown	unknown	gnl\|CDD\|274743
NC_011283.1\|WP_012540510.1\|621377_622412_+\|autoinducer-2-ABC-transporter-permease-LsrC	unknown	unknown	gnl\|CDD\|185330
NC_011283.1\|WP_008806564.1\|623413_624427_+\|autoinducer-2-ABC-transporter-substrate-binding-protein-LsrB	unknown	unknown	gnl\|CDD\|237961
NC_011283.1\|WP_002917724.1\|624438_625326_+\|3-hydroxy-5-phosphonooxypentane-2,4-dione-thiolase	unknown	unknown	gnl\|CDD\|181306
NC_011283.1\|WP_012540500.1\|607597_608587_-\|Gfo/Idh/MocA-family-oxidoreductase	unknown	unknown	gnl\|CDD\|223745
NC_011283.1\|WP_012540509.1\|619893_621381_+\|autoinducer-2-ABC-transporter-ATP-binding-protein-LsrA	unknown	unknown	gnl\|CDD\|185336
NC_011283.1\|WP_012540506.1\|614760_616782_-\|NADPH-dependent-2,4-dienoyl-CoA-reductase	unknown	unknown	gnl\|CDD\|239240
NC_011283.1\|WP_012540502.1\|609239_610883_-\|glycoside-hydrolase-family-43-protein	unknown	unknown	gnl\|CDD\|350114
NC_011283.1\|WP_012540508.1\|618703_619675_-\|transcriptional-regulator-LsrR	unknown	unknown	gnl\|CDD\|237962
NC_011283.1\|WP_012540498.1\|604875_606123_-\|serine/threonine-transporter-SstT	unknown	unknown	gnl\|CDD\|184190
NC_011283.1\|WP_012540507.1\|617073_618666_-\|autoinducer-2-kinase	unknown	unknown	gnl\|CDD\|182853
NC_011283.1\|WP_012540511.1\|622412_623417_+\|histidine-kinase	unknown	unknown	gnl\|CDD\|184998

Protein	Function_ID	Function_description	E-value
NC_011283.1\|WP_008806562.1\|627303_627858_-\|PadR-family-transcriptional-regulator	gnl\|CDD\|224609	COG1695, COG1695, Predicted transcriptional regulators [Transcription].	2.3632e-22
NC_011283.1\|WP_012540501.1\|608660_609161_-\|M48-family-metallopeptidase	gnl\|CDD\|224368	COG1451, COG1451, Predicted metal-dependent hydrolase [General function prediction only].	2.79808e-36
NC_011283.1\|WP_012540505.1\|613404_614535_+\|23S-rRNA-(guanine(1835)-N(2))-methyltransferase-RlmG	gnl\|CDD\|184963	PRK15001, PRK15001, 23S rRNA (guanine(1835)-N(2))-methyltransferase RlmG.	0
NC_011283.1\|WP_012540512.1\|625666_627046_-\|putrescine-aminotransferase	gnl\|CDD\|183175	PRK11522, PRK11522, putrescine--2-oxoglutarate aminotransferase; Provisional.	0
NC_011283.1\|WP_012540504.1\|611987_613328_+\|MFS-transporter	gnl\|CDD\|236610	PRK09669, PRK09669, putative symporter YagG; Provisional.	0
NC_011283.1\|WP_012540503.1\|611012_611879_-\|helix-turn-helix-transcriptional-regulator	gnl\|CDD\|225117	COG2207, AraC, AraC-type DNA-binding domain-containing proteins [Transcription].	1.41737e-18
NC_011283.1\|WP_002917723.1\|625322_625619_+\|(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione-isomerase	gnl\|CDD\|182494	PRK10486, PRK10486, (4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione isomerase.	6.90108e-61
NC_011283.1\|WP_012540497.1\|604305_604860_+\|YgjV-family-protein	gnl\|CDD\|378474	pfam10688, Imp-YgjV, Bacterial inner membrane protein. This is a family of inner membrane proteins. Many of the members are YgjV protein.	1.91098e-58
NC_011283.1\|WP_012540499.1\|606354_607326_-\|TerC-family-protein	gnl\|CDD\|274743	TIGR03718, R_switched_Alx, integral membrane protein, TerC family. Rfam model RF00080 describes a structured RNA element called the yybP-ykoY leader, or SraF, which may precede one or several genes in a genome. Members of this highly hydrophobic protein family often are preceded by a yybP-ykoY leader, which may serve as a riboswitch. From the larger group of TerC homologs (pfam03741), this subfamily contains TerC itself from Alcaligenes sp. plasmid IncHI2 pMER610 and from Proteus mirabilis. It also contains the alkaline-inducible E. coli protein Alx, which unlike the two TerC examples is preceded by a yybP-ykoY leader.	7.73273e-143
NC_011283.1\|WP_012540510.1\|621377_622412_+\|autoinducer-2-ABC-transporter-permease-LsrC	gnl\|CDD\|185330	PRK15432, PRK15432, autoinducer 2 ABC transporter permease LsrC; Provisional.	0
NC_011283.1\|WP_008806564.1\|623413_624427_+\|autoinducer-2-ABC-transporter-substrate-binding-protein-LsrB	gnl\|CDD\|237961	PRK15408, PRK15408, autoinducer 2 ABC transporter substrate-binding protein LsrB.	0
NC_011283.1\|WP_002917724.1\|624438_625326_+\|3-hydroxy-5-phosphonooxypentane-2,4-dione-thiolase	gnl\|CDD\|181306	PRK08227, PRK08227, 3-hydroxy-5-phosphonooxypentane-2,4-dione thiolase.	0
NC_011283.1\|WP_012540500.1\|607597_608587_-\|Gfo/Idh/MocA-family-oxidoreductase	gnl\|CDD\|223745	COG0673, MviM, Predicted dehydrogenases and related proteins [General function prediction only].	1.35805e-66
NC_011283.1\|WP_012540509.1\|619893_621381_+\|autoinducer-2-ABC-transporter-ATP-binding-protein-LsrA	gnl\|CDD\|185336	PRK15439, PRK15439, autoinducer 2 ABC transporter ATP-binding protein LsrA; Provisional.	0
NC_011283.1\|WP_012540506.1\|614760_616782_-\|NADPH-dependent-2,4-dienoyl-CoA-reductase	gnl\|CDD\|239240	cd02930, DCR_FMN, 2,4-dienoyl-CoA reductase (DCR) FMN-binding domain. DCR in E. coli is an iron-sulfur flavoenzyme which contains FMN, FAD, and a 4Fe-4S cluster. It is also a monomer, unlike that of its eukaryotic counterparts which form homotetramers and lack the flavin and iron-sulfur cofactors. Metabolism of unsaturated fatty acids requires auxiliary enzymes in addition to those used in b-oxidation. After a given number of cycles through the b-oxidation pathway, those unsaturated fatty acyl-CoAs with double bonds at even-numbered carbon positions contain 2-trans, 4-cis double bonds that can not be modified by enoyl-CoA hydratase. DCR utilizes NADPH to remove the C4-C5 double bond. DCR can catalyze the reduction of both natural fatty acids with cis double bonds, as well as substrates containing trans double bonds. The reaction is initiated by hybrid transfer from NADPH to FAD, which in turn transfers electrons, one at a time, to FMN via the 4Fe-4S cluster. The fully reduced FMN provides a hydrid ion to the C5 atom of substrate, and Tyr and His are proposed to form a catalytic dyad that protonates the C4 atom of the substrate and completes the reaction.	0
NC_011283.1\|WP_012540502.1\|609239_610883_-\|glycoside-hydrolase-family-43-protein	gnl\|CDD\|350114	cd09000, GH43_SXA-like, Glycosyl hydrolase family 43, such as Selenomonas ruminantium beta-D-xylosidase SXA. This glycosyl hydrolase family 43 (GH43) includes enzymes that have been characterized to mainly have beta-1,4-xylosidase (beta-D-xylosidase;xylan 1,4-beta-xylosidase; EC 3.2.1.37) activity, including Selenomonas ruminantium (Xsa;Sxa;SXA), Bifidobacterium adolescentis ATCC 15703 (XylC;XynB;BAD_0428) and Bacillus sp. KK-1 XylB. They are part of an array of hemicellulases that are involved in the final breakdown of plant cell-wall whereby they degrade xylan. They hydrolyze beta-1,4 glycosidic bonds between two xylose units in short xylooligosaccharides. These are inverting enzymes (i.e. they invert the stereochemistry of the anomeric carbon atom of the substrate) that have an aspartate as the catalytic general base, a glutamate as the catalytic general acid and another aspartate that is responsible for pKa modulation and orienting the catalytic acid. These enzymes possess an additional C-terminal beta-sandwich domain that restricts access for substrates to a portion of the active site to form a pocket. The active-site pockets comprise of two subsites, with binding capacity for two monosaccharide moieties and a single route of access for small molecules such as substrate. A common structural feature of GH43 enzymes is a 5-bladed beta-propeller domain that contains the catalytic acid and catalytic base. A long V-shaped groove, partially enclosed at one end, forms a single extended substrate-binding surface across the face of the propeller.	6.78152e-177
NC_011283.1\|WP_012540508.1\|618703_619675_-\|transcriptional-regulator-LsrR	gnl\|CDD\|237962	PRK15418, PRK15418, transcriptional regulator LsrR; Provisional.	0
NC_011283.1\|WP_012540498.1\|604875_606123_-\|serine/threonine-transporter-SstT	gnl\|CDD\|184190	PRK13628, PRK13628, serine/threonine transporter SstT; Provisional.	0
NC_011283.1\|WP_012540507.1\|617073_618666_-\|autoinducer-2-kinase	gnl\|CDD\|182853	PRK10939, PRK10939, autoinducer-2 (AI-2) kinase; Provisional.	0
NC_011283.1\|WP_012540511.1\|622412_623417_+\|histidine-kinase	gnl\|CDD\|184998	PRK15038, PRK15038, autoinducer 2 ABC transporter permease LsrD.	3.53211e-146

>NC_011283.1|WP_012540506.1|614760_616782_-|NADPH-dependent-2,4-dienoyl-CoA-reductase
MSRYPSLFAPLELGFTTLKNRVLMGSMHTGLEELPDGAQRLAAFYAERARHGVALIVTGGIAPAPSGVTMAGGAVLNDASHLAHHRHITDAVHQEGGKIALQILHTGRYSYQPALVAPSALQAPINRFTPHELSHDEILTLIDDFAHCAQLAREAGYDGVEVMGSEGYLINEFLAARTNQRDDQWGGDYARRMRFAIEVVKAVRQRAGHDFIIIYRLSMLDLVNDGSTLAEVTELAQAIEAAGATIINTGIGWHEARIPTIATPVPRGAFSWVTRKLKGAVSIPLITTNRINDPQVAEDILARGDADMVSMARPFLADAEFMSKAQRDRAGEINTCIGCNQACLDRIFVGKVTSCLVNPRACHETLMPVLPANAPKRLAVVGAGPAGLAFAVNAAARGHHVTLFDALPEIGGQFNIAKQIPGKEEFHETLRYYRTMLDLHGVDLRLNTRVTADDLLAFDETILATGIAPRLPAIDGIDHPKVLSYLDVLRDKAPVGAKVAIIGCGGIGFDTAMYLSQSGVATSQDIGEFCREWGIDTSLQTAGGLHPEGPQLSKSPRQIVMLQRKASKPGEGLGKTTGWIHRATLLARGVKMIPAVSYEKIDDEGLHVTIGGERQLLAVDQVVICAGQEPRRELADPLRAAGKTVHLIGGCDVAAELDARRAIAQGTKLALAI
>NC_011283.1|WP_012540505.1|613404_614535_+|23S-rRNA-(guanine(1835)-N(2))-methyltransferase-RlmG
MSQAELNGELFTLERFPPNAEEEALQAWEAADEYLLQQVNDVDGLTLIFNDGFGALACALAERNPVSINDSFISELATRHNLRMNGIDEESVRFQDSLSPLPAAPALVLIKVPKQLALLEQQLRALREVVTPETRIIAAAKARDVHNSTLALFEKILGTTTTSLAWKKARLIHCVFTAPKLADAPQTYSWKLDGTPWTIHNHANVFARSGLDIGARFFLQHLPSDLEGEIADLGCGNGVIGLQALAQNPNASVMFTDESHMAVASSRLNVERNLPDDIARCEFMVNNSLSGIEPDRFTAILCNPPFHQQHAITDHIAWQMFNDARRSLKYGGELYVVGNRHLDYFRKLKRAFGNCTTIATNNKFVILKATKVRKQR
>NC_011283.1|WP_012540504.1|611987_613328_+|MFS-transporter
MNTARINIKEKFSYGLGDTGCNLVWQTVMLFMAWFYTDVFGLSPAHMGTMFLAVRVLDAVTDVLMGAVADRTRTKYGQFRPYILWFAIPFGVLCCLTFYTPDLGYSGKLIYAYVSYTLLSLVYTAINVPYCAMINNISNDSRERVSLQSWRFALSTLGGLIVSLTALPLVAWLGKGNLQNGYFYTMMVMGALSIVLFFICFGLTKERYSTDITANNQSSILDDLKTLLANKDWRILFTLNVVNLIAVLFKGGTTLYYVNNIMGRADLGSLLLTTTLASGVVGAMLSPFIFKNIDKVKGFKLSMALEAVLLIAMYFVPAGNVAAIFTLVIIINIIQLAATPLQWSMLSDIIDAEEKRSGKKLSGIVFSTNLFAIKLGIAIGGALVGYLLAWGDYVGGAAQQSASALQMIKLLFTLFPGVLVALLIVIMNRYSLDDKRLSHMAQESGR
>NC_011283.1|WP_012540503.1|611012_611879_-|helix-turn-helix-transcriptional-regulator
MSDESPVFEKIPVGAGELFTLRADNINDFNGINVVPHFHMMDELMWFRESGGSYSIGDEKFTIKNNTLVYVPALLIHEMTLPPAASHKRYLMQFEKEWLEGYDLSLPAAHCGAVVYLSGEEAERLELLLSWCSEFSDFSDSLFRSLMQSVLLHAFNRLKDSVPVTERTHHRYLSELIELLQVINANENFEMTTEEAARRCQWSKSWFSRTFKSAFGISFKKFMLLRKLNIAVNLLTNTDLKISDISQSAGFTDSAYFCLKFKEMMNDTPQSFRHKIRSTDAVGSRAEK
>NC_011283.1|WP_012540502.1|609239_610883_-|glycoside-hydrolase-family-43-protein
MIQNPVFRGFNPDPCICRRGDDYYVAVSSFEWFPGLPVYHSRDLKHWQLLTHVLTDDNNPDLKKLPSAKGIWAPSLTWCEEEKLFYVIYGVMNSMNSRYFDVDNYLITAEEITGPWSAPVYLHSAGFDASILHDHDGRKWIVSLEWETREGYEKPGAICLVEYSPQTHSVIGYPQRIWHGGTDRGCIEAPHLTRRGDYYYLMVAEGGTGYGHSVTMARATEVAGPYQGDPLNPIVTSWPENFNERKDTGHLKPHYFNPETYLQKAGHGSYVETPTGEVWLTHLCSRPFRQELRCPLGRETAIQRMEWSEDGWLRLAAGGHLAQHQVEGSRLPPHPFPLKADLDDFDESRVDNAFYAPRIHFQRFTSLTRKAGYLALRGQESLSSLNKVSLLAKKLTSVYANISTKMDFNPEIYQHSAGLVLYYDNMNYLFLHKTWDETSGAAQLAIIYMDNGERHDDPQKIRLAEGEIYLAIAINGREVQCSWSVDGEHYHPIGAVYDTSHFSDEYSRYGEFTGAFVGMACVDSMLHRKEALFDFFCYRADEDAIIE
>NC_011283.1|WP_012540501.1|608660_609161_-|M48-family-metallopeptidase
MSTLPYLHGYPESLLSQVTALIEQDRLGEVLQKRYPQGHDVNSDKALYQYTQDLKARFLRGAAPINKVMYDSKIHVLNNALGLHTAISRVQGGKLKAKAEIRVATVFRDAPEAFLRMIVVHELAHLKEKDHNKAFYQLCCHMEPQYHQLEFDTRLWLTHLSLNRSA
>NC_011283.1|WP_012540500.1|607597_608587_-|Gfo/Idh/MocA-family-oxidoreductase
MIRFAVVGTNWITKQFVDAAHETGKYKLTAIYSRSLEQAQAFANDYPVEHLFTSLDDLAQSPDVDAVYIASPNSLHFPQTRLFLSHKKHVICEKPLASNLQEVEAAIALAKENNVVLFEAFKTASLPNFLLLKETLPKAGKLRKAFINYCQYSSRYQRYLDGENPNTFNPAFSNGSIMDIGFYCLASAVALWGEPRAVLATASLLDSGVDAQGTVVLSYGDFDVTLHHSKVSDSAIPSEIQGEDGTLVIEKISECQKLAFVPRGGKAQDLTQPQHINTMLYEAETFARLVETQDVNHPGLTVSRITAKLSSEIRRQTGVIFPADTQPLA
>NC_011283.1|WP_012540499.1|606354_607326_-|TerC-family-protein
MNTVGTPLLWGGFAVVVAIMLAIDLLLQGRRGSHSMTMKQAAGWSILWVTLSLLFNAAFWWYLVQTQGRAVADPQALAFLTGYLIEKALAVDNVFVWLMLFSYFAVPPALQRRVLVYGVLGAIVLRTIMIFAGSWLISQFDWLLYVFGAFLLFTGVKMALAKEDDSGIGDKPLVRWIRSHLRMTDKIESERFFTRKNGVLFATPLLLVLILVELSDVIFAVDSIPAIFAVTTDPFIVLTSNLFAILGLRAMYFLLAGVAERFSMLKYGLSVILVFIGVKMLIVDFYHIPVAISLGVVGGILTVTLLINAWVNKQHDKQRKLTE
>NC_011283.1|WP_012540498.1|604875_606123_-|serine/threonine-transporter-SstT
MTTRTPPSGWISRLAQGSLVKQILIGLVLGVLLALVSKPAAIAVGLLGTLFVGALKAVAPVLVLMLVMASIANHQHGQKTSIRPILFLYLLGTFSAALTAVLFSFVFPSTLHLTTAADSITPPSGIVEVLRGLLMSMVSNPIDALLNANYIGILVWAVGLGFALRHGNDTTKNLINDVSHAVTFIVKVVIRFAPLGIFGLVSSTLATTGFETLWGYAQLLLVLVGCMLLVALVINPLLVFWKIRRNPYPLVLTCLRESGVYAFFTRSSAANIPVNMALCEKLNLDRDTYSVSIPLGATINMAGAAITITVLTLAAVHTLNIPVDLPTALLLSVVASLCACGASGVAGGSLLLIPLACNMFGIPNDVAMQVVAVGFIIGVLQDSCETALNSSTDALFTAAACIAEDDQLAKNALRS
>NC_011283.1|WP_012540497.1|604305_604860_+|YgjV-family-protein
MTAYWLAQGVGVIAFLIGITTFINRDERRFRLQLAVYSAIIGVHFFLMGAGSAGMSAGLNALRTVISLRTRSLWVMTVFILLTLILGLGKLQHAMELLPIIGTVASTWALFRCKGLTVRCVMWCSTACWVTHNLWLGSIGGTLIEGSFLIVNGLNIIRFRRMQKRGIDPFKVENAVQEKSPSAR
>NC_011283.1|WP_012540507.1|617073_618666_-|autoinducer-2-kinase
MSYLLALDAGTGSIRAVIFDLNGRQLAVGQAEWKHLSVDNVPGSMEFDLTTNWQLACQCIRQALNAAGLSAADIQSVACCSMREGIVLYDRDGEAIWACANVDARASREVAELKEIHDYRFESEVYEVSGQTLALSAMPRLLWLAHHRPDIYRKAATITMISDWLAAKLSGELAVDPSNAGTTGMLDLFSRDWRPALLDMAGLRADMLSPVKETGTLLGAVTETAAQQSGLRAGTPVVMGGGDVQLGCLGLGVVRAGQTAVLGGTFWQQVVNLPQVRTDPQMNIRVNPHVIPGMAQAESISFFTGLTMRWFRDAFCAEEKLIAERLGVDAYSLLEEMASRVPAGSHGVMPIFSDAMHFKQWYHAAPSFINLSIDPEKCNKATLFRALEENAAIVSACNLAQISQFSGVTFESLVFAGGGSKGALWSQILSDVTGLPVRVPVVREATALGCAIAAGTGAGLYGDMASTGERLVSWHREFTPNPQHRELYQEMMSKWQTVYADQLGLVDSGLTTSMWQAPGLERRQRVAPSP
>NC_011283.1|WP_012540508.1|618703_619675_-|transcriptional-regulator-LsrR
MSEKRITEENRYAGLALAEEELVARVAWCYYHDGLTQNDIGERLGLPRLKISRLLEKGRQSGVIRVQINSRYEGCLALESELQQRFGLKIARVLPALNTPPMNTRLGIGAAQSLMGILQPGQLLAVGFGEATMSCLQHLSGFIGSQQVRLVTLSGGVGPYMTGIGQLDAACSVSIIPAPLRVSSAEVAEILRRESSVRDVILAATAADAAVVGIGAIDQRRDATILRSGYISEGEQLMYARKGAVGDILGYFLQADGRPVEGLEIHRELLGVTLDELAQLPTIVGVAGGEEKAQAIYAALTGKRINGLVTEETTARAVLALAS
>NC_011283.1|WP_012540509.1|619893_621381_+|autoinducer-2-ABC-transporter-ATP-binding-protein-LsrA
MKPLLEARQICKQFSGVAVLKGIDFTLGAGQVHALMGGNGAGKSTLMKIIAGVETPDSGELTIGDRAFARLSPALAHQLGIYLVPQEPMLFPNLSVRENILFRLPKRADTVARLQDKLRQLNCQINLDASASTLEVADQQMVEILRGLMREARILILDEPTASLTPGETERLFSQIRALQVLDVGIVFISHKLPEIRQLASHISVMRDGAVVLSGETAAYRDEQLINAMTPVSRDHALSDTQKLWLSLPGNRRTQPQDFPVLRVEDLTGEGFIDLNLEIRAGEIVGLAGLVGSGRTEFAETLYGLRPPRAGRIWLENREISRDSTRARLASGLVYLPEDRQVSGLFLDAPVRWNTVMFNQPSWWQQGKREAAVVERYHRALGIKLADGDQPVRTLSGGNQQKVLLARCLEANPLLLIVDEPTRGVDVSARADIYQLLKSVAAQNVAVLMISSDLDEFVGLADRVLVMHQGRYSGELARQAVTVDRMMTLAFGGQA
>NC_011283.1|WP_012540510.1|621377_622412_+|autoinducer-2-ABC-transporter-permease-LsrC
MKTLLKNRELSAFFAIVALFAVLVALNPAYFSLQTLAMIFASSQILCLLALGATLVMLTRNIDVSVGSTVGLCAIAVGVALNNGYGLATAIAFALAIGALAGAFNGLLVVGLRIPAIVATLGTLGLYRGVMLLWTGGKWIEGLPDSLKSLSEPAFIGVSPLGWLVLALLLAGGWLLSRTSFGRDFYAVGDNLAAARQLGVAVNRTRMLAFTLNGMLAACAGIVFAAQIGFVPNQTGSGLEMKAIAACVLGGISLLGGTGTLLGAFLGAFFLTQIDTVLVLFRLPAWWNDFIAGLVLLGVLVLDGRLRQALARHQRALKYSRFQPGNKGSKQVARFPERKSKEVA
>NC_011283.1|WP_012540511.1|622412_623417_+|histidine-kinase
MKLKLNWESALLALLIAEILLFGALNPRMLDLNMLLFSTSDFICIGIVALPLTLVIISGGIDISLGSTIGLCAIALGVMTQAAWPLWLAVSLTLLLGLLCGLFNAALIHYTGISPLVITLGTLYLYGGGALLLSGMAGATGYEGIGGFPDSFTAFANLTLAGLPLPLVLFAIITFLFWLLAHRGRFGRHLFLLGQNPRAARYAALSVNGIPYVLYGLVGVASAVAALVMVSYFGSARSDLGRDLLMPALTAAVLGGANIYGGSGSILGTALAALLVGYLQQGLQMVGIPNQVSSALSGALLVVVVMGRSLSLHREWVRATWRRLFSHRTIGAQQ
>NC_011283.1|WP_008806564.1|623413_624427_+|autoinducer-2-ABC-transporter-substrate-binding-protein-LsrB
MKTKRILQVSALALAMSVVTAQAADRIAFIPKLVGVGFFTSGGNGAKEAGKALGVDVTYDGPTEPSVSGQVQLINNFVNQGYNAIIVSAVSPDGLCPALKRAMQRGVKVLTWDSDTKPECRSIYINQGTPQQLGGLLVEMAEKQVSKPAAKVAFFYSSPTVTDQNQWVKEAKAKIEKEHPQWQIVTTQFGYNDATKSLQTAEGILKAYPDLDAIIAPDANALPAAAQAAENLKRQGVAIVGFSTPNVMRPYVERGTVKAFGLWDVVQQGKIAVNVADRLLKKGDLNVGDSVEVKDIGSLKVEPNSVQGYQYEAKGNGIVLLPERVVFSKENINNYDF
>NC_011283.1|WP_002917724.1|624438_625326_+|3-hydroxy-5-phosphonooxypentane-2,4-dione-thiolase
MADLDDIKEGKDFGIDRPQQNTLYTLKGCGSLDWGMQSRLARIFNPHSNRTVMLAFDHGYFQGPTTGLERIDLSIAPLFADTDVLMCTRGVLRSQVPAATNKPVVLRASGGNSILSELSNECVAVAMEDALRLNVCAVAAQVYIGSEYEHQSINNIIKLVDAGNRYGMPVLAVTGVGKEMTRDARYFSLASRIAAEMGAQFVKTYFVEEGFEKVTASCPVPIVIAGGKKLPEHEALEMCWRAIDQGASGVDMGRNIFQSSAPRAMLKAVKKVVHENLNAREAYQFWQEEKQGELK
>NC_011283.1|WP_002917723.1|625322_625619_+|(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione-isomerase
MNVTLVEINIKPERVDEFLEVFRANHEGALQEPGNLRFDVLQDPEVKTRFFIYEAYKDDEAVLAHKKTPHYLACVEKLEEMMSQPRQKRSFIGLLPQV
>NC_011283.1|WP_012540512.1|625666_627046_-|putrescine-aminotransferase
MNRLPSSASALACSAHALNLIEKRTLDHEEMKALNQEVREYFKEHVNPGFLEYRKSVTAGGDYGAVEWQAGGLNTLVDTQGQEFIDCLGGFGIFNVGHRNPVVVSAVENQLAKQPLHSQELLDPLRAMLAKTLAALTPGKLKYSFFCNSGTESVEAAIKLAKAYQSPRGKFTFIATSGAFHGKSLGALSATAKSTFRKPFMPLLPGFRHVPFGDINAMRTMLSECKKTGDDVAAVILEPIQGEGGVILPPQGYLPAVRKLCDEFGALLILDEVQTGMGRTGKMFACEHENVQPDILCLAKALGGGVMPIGATVATEEVFSVLFDNPFLHTTTFGGNPLACAAALATINVLLTQNLPAQAAQKGDMLLDGFRLLAQEYPDLVNEVRGKGMLMAIEFVDNEIGYDFASEMFRQRVLVAGTLNNAKTIRVEPPLTLTLEQCEQVLKAARKALAALRVSVEEA
>NC_011283.1|WP_008806562.1|627303_627858_-|PadR-family-transcriptional-regulator
MRHHHEEGRGPRGRHGDPSEHGDHGRRGGGRRQRFFGHGELRLIILDILSRNASHGYELIKEIETLTQGNYSPSPGVIYPTLDLLQDQGLISVEDDNGRKKIVISEEGKQLHAENQEHLAHIQERLQARMVGCELRRDPQMKRALENFKAVLDLKVNQQASSAAQLKQIIGIIDRAAMEISQLD

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Crispr_ID: NC_011283_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_011283_2

2316593-2316745

Orphan

I-E,II-B

Consensus_repeat	Method
TGTCTTCCCCACATGCGTGGGGGTGTTTCTA	CRISPRCasFinder

2 spacers

The CRISPR arrays of NC_011283_2

>merge|NC_011283|2|2316593-2316745|CRISPRCasFinder
TGTCTTCCCCACATGCGTGGGGGTGTTTCTAGCGGGCATCTGTAAGAACGGCTTTTCGCCATGTCTTCCCCACATGCGTGGGGGTGTGTCTAAAAAAGAAAAACTCTCCGGTTCCCTGTTCGGGTCTTCCCCACACGTGTGGGGCCTGTTTTC

>NC_011283|2|2|2316593-2316745|CRISPRCasFinder
TGTCTTCCCCACATGCGTGGGGGTGTTTCTA	GCGGGCATCTGTAAGAACGGCTTTTCGCCA
TGTCTTCCCCACATGCGTGGGGGTGTGTCTA	AAAAAGAAAAACTCTCCGGTTCCCTGTTCG
GGTCTTCCCCACACGTGTGGGGCCTGTTTTC

Protein	Signature genes	Signature genes Name	Protein_function
NC_011283.1\|WP_012541450.1\|2323686_2324424_+\|heme-ABC-transporter-permease	unknown	unknown	gnl\|CDD\|273492
NC_011283.1\|WP_012541451.1\|2324420_2324651_+\|heme-exporter-protein-CcmD	unknown	unknown	gnl\|CDD\|225656
NC_011283.1\|WP_004143391.1\|2324634_2325093_+\|cytochrome-c-maturation-protein-CcmE	unknown	unknown	gnl\|CDD\|183874
NC_011283.1\|WP_012541447.1\|2320933_2322274_+\|cytochrome-c	unknown	unknown	gnl\|CDD\|365823
NC_011283.1\|WP_012541445.1\|2317508_2317880_-\|VOC-family-protein	unknown	unknown	gnl\|CDD\|319923
NC_011283.1\|WP_012541440.1\|2310962_2312042_-\|malate/lactate/ureidoglycolate-dehydrogenase	unknown	unknown	gnl\|CDD\|182240
NC_011283.1\|WP_012541449.1\|2322977_2323637_+\|heme-exporter-protein-CcmB	unknown	unknown	gnl\|CDD\|200083
NC_011283.1\|WP_012541448.1\|2322357_2322981_+\|cytochrome-c-biogenesis-heme-transporting-ATPase-CcmA	unknown	unknown	gnl\|CDD\|184125
NC_011283.1\|WP_008804521.1\|2315270_2316341_+\|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|226361
NC_011283.1\|WP_012541436.1\|2305320_2305755_-\|VOC-family-protein	unknown	unknown	gnl\|CDD\|319923
NC_011283.1\|WP_002908285.1\|2319138_2320923_+\|GMC-family-oxidoreductase	unknown	unknown	gnl\|CDD\|225186
NC_011283.1\|WP_162493248.1\|2308361_2308523_+\|amidohydrolase	unknown	unknown	gnl\|CDD\|349916
NC_011283.1\|WP_041165351.1\|2316764_2317448_+\|DUF4926-domain-containing-protein	unknown	unknown	gnl\|CDD\|379816
NC_011283.1\|WP_012541434.1\|2304159_2304744_-\|TetR/AcrR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|224228
NC_011283.1\|WP_012541435.1\|2304886_2305279_-\|VOC-family-protein	unknown	unknown	gnl\|CDD\|319923
NC_011283.1\|WP_012541439.1\|2308565_2310716_-\|formate-dehydrogenase-subunit-alpha	unknown	unknown	gnl\|CDD\|130652
NC_011283.1\|WP_012541442.1\|2312345_2313434_+\|ABC-transporter-substrate-binding-protein	unknown	unknown	gnl\|CDD\|224753
NC_011283.1\|WP_008804520.1\|2313508_2315278_+\|iron-ABC-transporter-permease	unknown	unknown	gnl\|CDD\|224099
NC_011283.1\|WP_012541437.1\|2305869_2307069_-\|MFS-transporter	unknown	unknown	gnl\|CDD\|341030
NC_011283.1\|WP_012541446.1\|2318380_2319136_+\|gluconate-2-dehydrogenase-subunit-3-family-protein	unknown	unknown	gnl\|CDD\|379295

Protein	Function_ID	Function_description	E-value
NC_011283.1\|WP_012541450.1\|2323686_2324424_+\|heme-ABC-transporter-permease	gnl\|CDD\|273492	TIGR01191, Heme_exporter_protein_C, heme exporter protein CcmC. This model describes the cyt c biogenesis protein encoded by ccmC in bacteria. It must be noted an arabidopsis, a tritcum and a piscum plant proteins were recognizable in the clade. Quite likely they are of organellar origin. Bacterial c-type cytocromes are located on the periplasmic side of the cytoplasmic membrane. Several gene products encoded in a locus designated as 'ccm' are implicated in the transport and assembly of the functional cytochrome C. This cluster includes genes, ccmA;B;C;D;E;F;G and H. The posttranslational pathway includes the transport of heme moiety, the secretion of the apoprotein and the covalent attachment of the heme with the apoprotein. The proteins ccmA and B represent an ABC transporter; ccmC and D participate in the heme transfer to ccmE, which function as a periplasmic heme chaperone. The presence of ccmF, G and H is suggested to be obligatory for the final functional assembly of cytochrome c. [Protein fate, Protein and peptide secretion and trafficking, Transport and binding proteins, Other].	3.13129e-86
NC_011283.1\|WP_012541451.1\|2324420_2324651_+\|heme-exporter-protein-CcmD	gnl\|CDD\|225656	COG3114, CcmD, Heme exporter protein D [Intracellular trafficking and secretion].	5.20572e-17
NC_011283.1\|WP_004143391.1\|2324634_2325093_+\|cytochrome-c-maturation-protein-CcmE	gnl\|CDD\|183874	PRK13165, PRK13165, cytochrome c maturation protein CcmE.	1.99416e-83
NC_011283.1\|WP_012541447.1\|2320933_2322274_+\|cytochrome-c	gnl\|CDD\|365823	pfam00034, Cytochrom_C, Cytochrome c. The Pfam entry does not include all Prosite members. The cytochrome 556 and cytochrome c' families are not included. All these are now in a new clan together. The C-terminus of DUF989, pfam06181, has now been merged into this family.	2.32094e-12
NC_011283.1\|WP_012541445.1\|2317508_2317880_-\|VOC-family-protein	gnl\|CDD\|319923	cd07262, VOC_like, uncharacterized subfamily of vicinal oxygen chelate (VOC) family. The vicinal oxygen chelate (VOC) superfamily is composed of structurally related proteins with paired beta.alpha.beta.beta.beta motifs that provide a metal coordination environment with two or three open or readily accessible coordination sites to promote direct electrophilic participation of the metal ion in catalysis. VOC domain is found in a variety of structurally related metalloproteins, including the bleomycin resistance protein, glyoxalase I, and type I ring-cleaving dioxygenases. A bound metal ion is required for protein activities for the members of this superfamily. A variety of metal ions have been found in the catalytic centers of these proteins including Fe(II), Mn(II), Zn(II), Ni(II) and Mg(II). The protein superfamily contains members with or without domain swapping. The proteins of this family share three conserved metal binding amino acids with the type I extradiol dioxygenases, which shows no domain swapping.	9.85422e-42
NC_011283.1\|WP_012541440.1\|2310962_2312042_-\|malate/lactate/ureidoglycolate-dehydrogenase	gnl\|CDD\|182240	PRK10098, PRK10098, putative dehydrogenase; Provisional.	0
NC_011283.1\|WP_012541449.1\|2322977_2323637_+\|heme-exporter-protein-CcmB	gnl\|CDD\|200083	TIGR01190, Heme_exporter_protein_B, heme exporter protein CcmB. This model describes the cyt c biogenesis protein encoded by ccmB in bacteria. Bacterial c-type cytochromes are located on the periplasmic side of the cytoplasmic membrane. Several gene products encoded in a locus designated as 'ccm' are implicated in the transport and assembly of the functional cytochrome C. This cluster includes genes: ccmA;B;C;D;E;F;G and H. The posttranslational pathway includes the transport of heme moiety, the secretion of the apoprotein and the covalent attachment of the heme with the apoprotein. The proteins ccmA and B represent an ABC transporter; ccmC and D participate in heme transfer to ccmE, which function as a periplasmic heme chaperone. The presence of ccmF, G and H is suggested to be obligatory for the final functional assembly of cytochrome C. [Protein fate, Protein and peptide secretion and trafficking, Transport and binding proteins, Other].	6.14574e-71
NC_011283.1\|WP_012541448.1\|2322357_2322981_+\|cytochrome-c-biogenesis-heme-transporting-ATPase-CcmA	gnl\|CDD\|184125	PRK13538, PRK13538, cytochrome c biogenesis heme-transporting ATPase CcmA.	1.74212e-106
NC_011283.1\|WP_008804521.1\|2315270_2316341_+\|ABC-transporter-ATP-binding-protein	gnl\|CDD\|226361	COG3842, PotA, ABC-type spermidine/putrescine transport systems, ATPase components [Amino acid transport and metabolism].	1.35987e-144
NC_011283.1\|WP_012541436.1\|2305320_2305755_-\|VOC-family-protein	gnl\|CDD\|319923	cd07262, VOC_like, uncharacterized subfamily of vicinal oxygen chelate (VOC) family. The vicinal oxygen chelate (VOC) superfamily is composed of structurally related proteins with paired beta.alpha.beta.beta.beta motifs that provide a metal coordination environment with two or three open or readily accessible coordination sites to promote direct electrophilic participation of the metal ion in catalysis. VOC domain is found in a variety of structurally related metalloproteins, including the bleomycin resistance protein, glyoxalase I, and type I ring-cleaving dioxygenases. A bound metal ion is required for protein activities for the members of this superfamily. A variety of metal ions have been found in the catalytic centers of these proteins including Fe(II), Mn(II), Zn(II), Ni(II) and Mg(II). The protein superfamily contains members with or without domain swapping. The proteins of this family share three conserved metal binding amino acids with the type I extradiol dioxygenases, which shows no domain swapping.	5.91448e-36
NC_011283.1\|WP_002908285.1\|2319138_2320923_+\|GMC-family-oxidoreductase	gnl\|CDD\|225186	COG2303, BetA, Choline dehydrogenase and related flavoproteins [Amino acid transport and metabolism].	4.91814e-80
NC_011283.1\|WP_162493248.1\|2308361_2308523_+\|amidohydrolase	gnl\|CDD\|349916	cd05666, M20_Acy1-like, M20 Peptidase aminoacylase 1 subfamily. Peptidase M20 family, uncharacterized subfamily of bacterial proteins predicted as putative amidohydrolases or hippurate hydrolases. These are a class of zinc binding homodimeric enzymes involved in hydrolysis of N-acetylated proteins. N-terminal acetylation of proteins is a widespread and highly conserved process that is involved in protection and stability of proteins. Several types of aminoacylases can be distinguished on the basis of substrate specificity. Aminoacylase 1 (ACY1) breaks down cytosolic aliphatic N-acyl-alpha-amino acids (except L-aspartate), especially N-acetyl-methionine and acetyl-glutamate into L-amino acids and an acyl group. However, ACY1 can also catalyze the reverse reaction, the synthesis of acetylated amino acids. ACY1 may also play a role in xenobiotic bioactivation as well as the inter-organ processing of amino acid-conjugated xenobiotic derivatives (S-substituted-N-acetyl-L-cysteine).	2.08406e-21
NC_011283.1\|WP_041165351.1\|2316764_2317448_+\|DUF4926-domain-containing-protein	gnl\|CDD\|379816	pfam16277, DUF4926, Domain of unknown function (DUF4926). This family consists of uncharacterized proteins around 70 residues in length and is mainly found in various Caulobacter, Microcystis and Cyanothece species. The function of this family is unknown.	1.27529e-17
NC_011283.1\|WP_012541434.1\|2304159_2304744_-\|TetR/AcrR-family-transcriptional-regulator	gnl\|CDD\|224228	COG1309, AcrR, Transcriptional regulator [Transcription].	8.03604e-12
NC_011283.1\|WP_012541435.1\|2304886_2305279_-\|VOC-family-protein	gnl\|CDD\|319923	cd07262, VOC_like, uncharacterized subfamily of vicinal oxygen chelate (VOC) family. The vicinal oxygen chelate (VOC) superfamily is composed of structurally related proteins with paired beta.alpha.beta.beta.beta motifs that provide a metal coordination environment with two or three open or readily accessible coordination sites to promote direct electrophilic participation of the metal ion in catalysis. VOC domain is found in a variety of structurally related metalloproteins, including the bleomycin resistance protein, glyoxalase I, and type I ring-cleaving dioxygenases. A bound metal ion is required for protein activities for the members of this superfamily. A variety of metal ions have been found in the catalytic centers of these proteins including Fe(II), Mn(II), Zn(II), Ni(II) and Mg(II). The protein superfamily contains members with or without domain swapping. The proteins of this family share three conserved metal binding amino acids with the type I extradiol dioxygenases, which shows no domain swapping.	3.73013e-41
NC_011283.1\|WP_012541439.1\|2308565_2310716_-\|formate-dehydrogenase-subunit-alpha	gnl\|CDD\|130652	TIGR01591, Formate_dehydrogenase_subunit_alpha, formate dehydrogenase, alpha subunit, archaeal-type. This model describes a subset of formate dehydrogenase alpha chains found mainly archaea but also in alpha and gamma proteobacteria and a small number of gram positive bacteria. The alpha chain contains domains for molybdopterin dinucleotide binding and molybdopterin oxidoreductase (pfam01568 and pfam00384, respectively). The holo-enzyme also contains beta and gamma subunits. The enzyme catalyzes the oxidation of formate (produced from pyruvate during anaerobic growth) to carbon dioxide with the concomitant release of two electrons and two protons. The enzyme's purpose is to allow growth on formate in some circumstances and, in the case of FdhH in gamma proteobacteria, to pass electrons to hydrogenase (by which process acid is neutralized). This model is well-defined, with only a single fragmentary sequence falling between trusted and noise. The alpha subunit of a version of nitrate reductase is closely related.	0
NC_011283.1\|WP_012541442.1\|2312345_2313434_+\|ABC-transporter-substrate-binding-protein	gnl\|CDD\|224753	COG1840, AfuA, ABC-type Fe3+ transport system, periplasmic component [Inorganic ion transport and metabolism].	4.25045e-48
NC_011283.1\|WP_008804520.1\|2313508_2315278_+\|iron-ABC-transporter-permease	gnl\|CDD\|224099	COG1178, ThiP, ABC-type Fe3+ transport system, permease component [Inorganic ion transport and metabolism].	1.46439e-102
NC_011283.1\|WP_012541437.1\|2305869_2307069_-\|MFS-transporter	gnl\|CDD\|341030	cd17477, MFS_YcaD_like, YcaD and similar transporters of the Major Facilitator Superfamily. This family is composed of Escherichia coli MFS-type transporter YcaD, Bacillus subtilis MFS-type transporter YfkF, and similar proteins. They are uncharacterized transporters belonging to the Major Facilitator Superfamily (MFS) of membrane transport proteins, which are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	1.59233e-58
NC_011283.1\|WP_012541446.1\|2318380_2319136_+\|gluconate-2-dehydrogenase-subunit-3-family-protein	gnl\|CDD\|379295	pfam13618, Gluconate_2-dh3, Gluconate 2-dehydrogenase subunit 3. This family corresponds to subunit 3 of the Gluconate 2-dehydrogenase enzyme that catalyzes the conversion of gluconate to 2-dehydro-D-gluconate EC:1.1.99.3.	7.61307e-40

>NC_011283.1|WP_008804521.1|2315270_2316341_+|ABC-transporter-ATP-binding-protein
MIELSVENLHLTYGDNPVLKGVSMTLGRGEVVSLLGPSGSGKTTLLRAVAGLEKPTSGRIAIGNRTVYDGTPRSEIPAEERNLGLVFQSYALWPHKTVFDNVAYPLKLRKVAAGEIKERVQRVLDQLGLGHLGNRHPHQLSGGQQQRVAIGRALVYNPPVILLDEPLSNLDAKLREEARVFLRELIIKLGLSALMVTHDQNEAMAISDRILLLNNGVIEQQGTPQEMYGSPATLFAAEFMGSNNRLHGKVTALENGRARVEGASWTLWGRAGEGVSVGQPATAVIRVERLRLDGAAQDNSLQLPLLTSMYLGDRWEYLFRTEGDDFPLRAYGTALRDAEHCHLTLPAEDVWIFPQR
>NC_011283.1|WP_008804520.1|2313508_2315278_+|iron-ABC-transporter-permease
MNVLRRKWQGLPRGVVVCITALVIYVPLLFIVVQSFLSAPFFSRSKSWSLEAFAFIFTDPDFYLALRSGFILAFGLVIIAIPLGGILAFLMVRTDLPGRRIIEPLILVPIFVSPMVLGFGYVVAAGPVGFFSQWAQQLIGFVPWNIYSMFSIVVIAGLTHVPHAYLYISSALRSVGSDVEEAARTVGATPLQVMTSVSLPMVRPSILYACVLLFFLGLEVFGLMLVLGDPEGNMVLATYLYKLTNKLGTPSYHLMAAVAVVLICITIPLVMLQRRLMRTANRFVTMKGKASQARALPLGKWRWVAGAVVVAWLTVTIGVPLLGVALRAFISNWGVGVSLWDELSLATFHNIWQQPNLLRAIVNSMAIGIVGGALAVICYLFVGIAMHRKADNVTRFLDYSVLVPRAVPGLLAGLAFLWVFLFVPMWLDQSLKHGWLSALPVADWLREHLIVQLRALRNTIFSVWLAYTVVWMAYGLRLISSTLLQVGPELEEAARSTGASRGQITRHVTVPLSRYGLIGSWLLMFLIFEREYSTGVYLLSPGTETIGSMLVSLWAAGAIDIVAALSFINILLVVIGLGIALRFGVKLHD
>NC_011283.1|WP_012541442.1|2312345_2313434_+|ABC-transporter-substrate-binding-protein
MYKKISGLVVSLTAVFACAAWAEVPAGYPADYQKTVDAAVKEGKVVIYSTTDTKAAGPLIKGFEAQYPGVKVEYNDMNSTELYNRYISEQAAGGGSGDVVWSSSMDTALKLATEYAEQYASPEVKQLPDWAVWQQKAYGTTYEPVVFIYNKRLIPQNEVPDSHTALAKLIASQADKFKGKVTTYDIEKSGLGFMLAVQDSQADANYFADLANIAKGGLTVQSSTGTMMERVSSGENLIGYNILGSYAEARAKNDPSLGIAYPKDYVLVLSRVSFISQESEHPNAAKLWLDYVLSEKGQQILASQADIPSIRRDIEGKNDIDGMTALLGKALKPIPVNETLLDYLQPQKRLQFIKQWRSAAAK
>NC_011283.1|WP_012541440.1|2310962_2312042_-|malate/lactate/ureidoglycolate-dehydrogenase
MPTGHRFLATDLHQFVVSLFTHLGSTSGEATLVADHLIAANLAGHDSHGVGMIPSYVKSHAGGFLQLNRHATVTKDAGAVVTLDGNAGFGQVVAHEAMQLGIEKAKQHGMAAIALRNAHHVGRIGYWAEQCAAAGLISIHFVSVIGDPMVAPFRGKDSRFGTNPLCVVFPREGHPPLLLDYATSAIAFGKTRVAWHKGEAVAPGCLIDAKGLPTTDPAVMQTSPLGALLTFAQHKGYALATLCEVLGGALSGGQTTHQESLQTSVDAIFNCMTTVILRPDAFDAPDSQAQTEAFIAWCKQSPHDADAPVLAPGEWEAANREARLAQGIPLDAGSWQAICAAARDVGLSESHFDRCRPLA
>NC_011283.1|WP_012541439.1|2308565_2310716_-|formate-dehydrogenase-subunit-alpha
MKKITSVCPYCGAGCKLKLVVDNNKIIRAEAADGVTNQNQLCLKGYYGWDFLNDTQLLTPRLKQPMIRYQKGGAFTPVSWQEAIRYTASKLREIKEKHGPRAIMTTGSSRGTGNETNYVMQKFARAVLNTNNVDCCARVCHGPSVAGLQQALGNGAMSNSISDIENSKCLLVFGYNCADSHPIVARRVIKARENGAKIIVCDPRRIETARIADRHLQLNNGSNMALVNAFGYVLLEEELYNKAYVERYTEGLDAYREAVKDYAPEAVEAIVGVSAQAIREAMRIFASAPSATIMWGMGVTQFGQAVDVVRGLASLALLTGNLGRANVGVGPVRGQNNVQGACDMGVLPNLFPGYQEVTDPAVREKFAAAWGVDPALMDDQVGTRITEVPHKALTGEIKAYYIMGEDPLQTEADLGLVRKGIEALDFVVVQDIFMTKTAEIADVLLPATSWGEHGGVFTCADRGFQRFEQAIPPAGNVKRDWEIISLLASEMGYPMHYENNQQIWDEMRELCPLFYGVTWEKMGDMGHVQWPCPTLDHPGTPWLYKDNRFDTPSGKGQLFATAWRAPAERPDDEWPLVLCTVREVGHYSCRSMTGNCAALQSLADEPGRVQMNPVDAQRLGIADKQLVWVSSRRGKVITRADLSDRINPGAVYMTYQWWVGACNELTQDNLDPISKTPETKYCAVKVEAIADQQWAERYAWTAYSDMKARLKAAADV
>NC_011283.1|WP_162493248.1|2308361_2308523_+|amidohydrolase
MLEVCPGAYFWIGTDGETPSKPLHNASYDFNDALISPGVAMWVALVEKQLPAA
>NC_011283.1|WP_012541437.1|2305869_2307069_-|MFS-transporter
MFNPDQNRLAPTLAMIMAASLVGFITGYTVPLISLELAQQQIAPLYVGLLAALPPAGMMISSFLSPALCRRVEMGVLLSGSLILLALATIASCMTTDMTLLLLPRLLTGLASGVIIVLGESWITGGAAGSQRATLTGIYASAFTGCQLAGPLLISVGPAWQASALMAIVAVTAVCLLMLRHLPTGTRESLGERASWRSLGAFLPVLASGVFCFAFFDASILALLPLYGMDKGLNEGMAVLLVTVVLTGDAMFQTPLGWLADRVGIRRVHLSCAVVFSLSLLALPLMLGSRIQLMAICLLLGAAAGALYTLSLVRAGKTFNGQKLIMINALFGFFWSAGSVAGPVVSGMLIGITGYDGLIVTLVASGVLFLLIQCLCKNEKTLLASEQEEEMDEATESAR
>NC_011283.1|WP_012541436.1|2305320_2305755_-|VOC-family-protein
MESNTLHRGRLIDHILLVVEDFEASKDFYTAVLSALEIPVITTANDYLLADELVVASRYSPEAAGKLTGRHHLAFQARDRDRVDAFYHAALTHGGRDNGAPGERHYHPGYYAAFVLDPQGNNIEAVYHGEAERSAGSVAISFTQ
>NC_011283.1|WP_012541435.1|2304886_2305279_-|VOC-family-protein
MFSYIMLGTNDLPRAIKFYDPLMALLGHVKAGRNEQGASWGTFNGNHTCGLCVGTPFDQQPAGVGNGTMVALNARSIEHIAELHALALQLGGRDEGGPGHRPQYGDAFHSAYVRDPDGNKLAFVYYASAV
>NC_011283.1|WP_012541434.1|2304159_2304744_-|TetR/AcrR-family-transcriptional-regulator
MIERSPKAREIMANTRQLLTVGGYKSFSYADLAERVGIRKASIHHHFPSKEDLVHAVVQEYRAEARAGMEAMDQQIHDPLIKVKGYADFWSACIKDGTSSFCICVMLAVELPTLPADIAAEVTGHFSDLSDWLASLLRAGETQGVFKLNETAEVEASALMAGIHGAMLAARAFNNPLVFDQIAWPLINKIIKVA
>NC_011283.1|WP_041165351.1|2316764_2317448_+|DUF4926-domain-containing-protein
MKRAELDVVVLGEDLPNEGLVKGTLGTIVMVFNAPTTGYLVEFCDEKGKTIAMPVLFPAQLKRYFTIGNLKSLMVEGNYPVADPVDPDVMADLMHKVAPAEWEDKKRRVYEDIQRLLISRPDYADMFNIMDGGEYNGMTLYSLVQAENGEPAWSNIFVRNFETRINEIYVDPNLNDKVVIGEEGMSVIVYSFTDDRFEIRDKVSSDYVIESHTHFTGLLSALIESVS
>NC_011283.1|WP_012541445.1|2317508_2317880_-|VOC-family-protein
MFDHVKFGASDYAASKTFFLQALAPLGVTLVGEGEPSYGAELAGSGDVSLCLYQSAEKPAPLHIAFRADSREQVDAFWQAALAAGGKDNGAPGVRPNYHASYYAAFVIAPDGHNIEAVCHLAG
>NC_011283.1|WP_012541446.1|2318380_2319136_+|gluconate-2-dehydrogenase-subunit-3-family-protein
MMSSEKTNNSRRDFLVKSMALIPTVVIGGAGAGAIGVATSATAQAAPASELASGNTAAASDWKPQFFNDREWAFINAAVARLIPADELGPGAKEAGVPEFIDRQLNTPYATGSIWYMQGPFNPDVPKEMGYQLPLVPKQIYNLGIADAEAWCQDKYHKTFAELSNEQQDEALGLWESGKAEFKQLPASLFFTYLLQNTREGFFSDPIHGGNKGMVGWTLINFPGARADFMDWVERGERYPFPPVSINGERA
>NC_011283.1|WP_002908285.1|2319138_2320923_+|GMC-family-oxidoreductase
MATVLKKTDVAIVGFGWVGAIMAKELTEAGLNVVALERGPMRDTWPDGAYPQVIDELTYNIRRKLFQDLSKSTVTIRHNTSQQAVPYRQLAAFLPGTGVGGAGLHWSGVHFRVDPIELRMRSHYEERYGKNFIPQDMIIQDFGVTYDELEPFFDKAEKVFGTSGTAWSIKGKVVGKGRGGNAFAPDRSDDFPLPAQKNTWSAQLFEKAALEVGYHPYNLPSANTSDSYTNPYGAQMGPCNFCGFCSGYACYMYSKASPNVNILPALRQEKRFELRTNANVLKVNLTDDKSRATGVTYVDGQGREMEQPADLVIIGAFQFHNVHLMLLSGIGKPYNPETGEGVVGRNFAYQNMTTIKAIFDKDTYTNPFIGAGGNGVGVDDFNADNFDHGAAGFVGGSPFWVNQAGTKPISGFPVPPGTPAWGSKWKAAVADTYTHHLSMDAHGAHQSYRQNYLDLDPNYKNVFGQPLLRMTFDWQENDIKMAQFMFDKMAPIAKAMKPKYILGSPKNANSHFDTTTYQTTHMNGGAVMGEDPKTSAVNRYLQSWDVHNVFVIGASAFPQGLGYNPTGTVAALAYWSAKAIREQYLKNPGPLVQA
>NC_011283.1|WP_012541447.1|2320933_2322274_+|cytochrome-c
MMKMQWLSALVLGALSCAAFAEEAPADSNLIKQGEYLARAGDCVACHTNGKAGKPFAGGLPMETPIGTIYSTNITPDKEHGIGGYTFEEFDDAVRKGVRKDGSTLYPAMPYPSFARISEADMRAMYAYFMHGVEPVNAANKDTDIPWPLSMRWPLAFWRGIFAPTPSDFVANPQVDPVLERGRYLVEGLGHCGACHTPRSLTMQEKALSESEGDDYLAGSNAPIDGWVASSLRGENRDGLGTWSEAELAEFLKTGRNDKSVVFGGMSDVVEHSLQYLSDDDITAIARYLKSLPPRGGKQTPAPVEDSVAKDLWKGNDSKTGAALYVDNCAACHRTDGAGYKRAFPSLKGNPVVQTEDATSLIHIVLTGSTTPAVKDAVSNLTMPSFGWRLDDQQVADVVNFIRTSWGNNAPAVSASDVAKVRKETAAHDEKALGNADISKLPGAGQ
>NC_011283.1|WP_012541448.1|2322357_2322981_+|cytochrome-c-biogenesis-heme-transporting-ATPase-CcmA
MLHAERLTCIVDDRPLFAALTLSLAAGELLQVAGDNGAGKTSLLRILCGLARPESGVVSWQGQPLAKVRESFHRQLLWLGHKPGVNAALTADENLRFFFPSSRLQQRESALAAVGLAGYEDLPLSQLSAGQQRRVALTRLWLTDAPLWILDEPFTALDATAMETLTRRLEQHARQGGSAILTTHQPLRPLRCPLRTLRLGGDAGGGQ
>NC_011283.1|WP_012541449.1|2322977_2323637_+|heme-exporter-protein-CcmB
MMRALLARELRLAWRSGAEILNPLWFFLIVITLFPFGVGAAPQLLAQIAPGVVWVAALLAALLVMDRLFRDDWQDGSLEQLLLLPTPLAAVVLVKVVAHWMMSGLPLLIVSPLAALLLGMSLHDAGVLALTLLLGTPTLSFLGAVGVGLTVGLKRGGVLLSLLVLPLAVPLLIFATAACQAAAAGLPVSGYLAMLAAFLTASATLCPFATAAALRLTVQ
>NC_011283.1|WP_012541450.1|2323686_2324424_+|heme-ABC-transporter-permease
MWKALHQLAIPERLYRLCGCWIPWLAALSALLLVIGLGWGFGFAPADYQQGESYRIMYLHVPAAMWSMGLYLAMAVAAFVGVVWQIKMADLAIAALAPVGAVCTLVALVSGAAWGKPMWGTWWIWDARLTSELVLLFLYAGVIALWHAFDDRRLAGRAAGILVLVGVVNLPIIHYSVYWWNTLHQGSTNLQQTIDPSMRLPLRICIFAFLMLSVTLTLMRLRNLILQLERRRPWVVALVNKGVAR
>NC_011283.1|WP_012541451.1|2324420_2324651_+|heme-exporter-protein-CcmD
MSPAFSSFAAFLDMGGYAVYVWLAVAVAVAAFGLLTVHTLWARRALFHEVRRQQARERRIAAAREHDKETADASAS
>NC_011283.1|WP_004143391.1|2324634_2325093_+|cytochrome-c-maturation-protein-CcmE
MQARRKTRLYIVLAVLAGLGLTVSLTLYALSSNIDLFYTPGEIIYGKTETRALPHTGQRLRVGGYVQPGSLQRDPQTLDVRFKLYDARGVVDVSYKGILPDLFREGQGVVAQGVLDGERHITAQQVLAKHDENYTPPEVKNAMTPEKTGAQP

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Crispr_ID: NC_011283_3

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_011283_3

3997660-3997766

Orphan

Consensus_repeat	Method
CCCTCTCCCATAGGGAGAGGGAGCA	CRISPRCasFinder

1 spacers

The CRISPR arrays of NC_011283_3

>merge|NC_011283|3|3997660-3997766|CRISPRCasFinder
CCCTCTCCCATAGGGAGAGGGAGCACACCCTAAAAAAGGCCATTGTCATTGCCTTTTTGCGTTTACCTTGCCCTCACCCCAACCCTCTCCCACAGGGAGAGGGAGCA

>NC_011283|3|3|3997660-3997766|CRISPRCasFinder
CCCTCTCCCATAGGGAGAGGGAGCA	CACCCTAAAAAAGGCCATTGTCATTGCCTTTTTGCGTTTACCTTGCCCTCACCCCAA
CCCTCTCCCACAGGGAGAGGGAGCA

Protein	Signature genes	Signature genes Name	Protein_function
NC_011283.1\|WP_012542481.1\|4003021_4004110_+\|oxidoreductase	unknown	unknown	gnl\|CDD\|182570
NC_011283.1\|WP_187148210.1\|3990597_3991548_+\|substrate-binding-domain-containing-protein	unknown	unknown	gnl\|CDD\|380501
NC_011283.1\|WP_008805590.1\|4006062_4008168_-\|carbon-starvation-protein-CstA	unknown	unknown	gnl\|CDD\|184976
NC_011283.1\|WP_008805596.1\|3999275_4000340_-\|sugar-ABC-transporter-substrate-binding-protein	unknown	unknown	gnl\|CDD\|380528
NC_011283.1\|WP_008805607.1\|3985662_3986271_-\|methylthioribulose-1-phosphate-dehydratase	unknown	unknown	gnl\|CDD\|236415
NC_011283.1\|WP_012542480.1\|4001355_4002858_-\|sugar-ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|224053
NC_011283.1\|WP_012542478.1\|3997930_3999172_-\|LVIVD-repeat-containing-protein	unknown	unknown	gnl\|CDD\|227601
NC_011283.1\|WP_012542474.1\|3986722_3987985_+\|cytosine-permease	unknown	unknown	gnl\|CDD\|236821
NC_011283.1\|WP_012542475.1\|3987981_3989217_+\|PucR-family-transcriptional-regulator-ligand-binding-domain-containing-protein	unknown	unknown	gnl\|CDD\|377939
NC_011283.1\|WP_012542482.1\|4005371_4005776_+\|helix-turn-helix-transcriptional-regulator	unknown	unknown	gnl\|CDD\|238045
NC_011283.1\|WP_008805601.1\|3992589_3993948_+\|MFS-transporter	unknown	unknown	gnl\|CDD\|340870
NC_011283.1\|WP_012068432.1\|4004167_4004911_+\|3-oxoacyl-ACP-reductase-FabG	unknown	unknown	gnl\|CDD\|235500
NC_011283.1\|WP_008805600.1\|3993974_3995243_+\|histidine-phosphatase-family-protein	unknown	unknown	gnl\|CDD\|366031
NC_011283.1\|WP_002893903.1\|4005772_4005970_-\|YbdD/YjiX-family-protein	unknown	unknown	gnl\|CDD\|225434
NC_011283.1\|WP_008805599.1\|3995303_3996332_-\|S-methyl-5-thioribose-1-phosphate-isomerase	unknown	unknown	gnl\|CDD\|273112
NC_011283.1\|WP_012542477.1\|3996433_3997633_+\|S-methyl-5-thioribose-kinase	unknown	unknown	gnl\|CDD\|236561
NC_011283.1\|WP_008805592.1\|4005094_4005397_+\|type-II-toxin-antitoxin-system-RelE/ParE-family-toxin	unknown	unknown	gnl\|CDD\|224937
NC_011283.1\|WP_012542479.1\|4000360_4001359_-\|ABC-transporter-permease	unknown	unknown	gnl\|CDD\|224093
NC_011283.1\|WP_008805602.1\|3991669_3992479_+\|inositol-monophosphatase	unknown	unknown	gnl\|CDD\|223559
NC_011283.1\|WP_008805604.1\|3989213_3990452_+\|cytosine-deaminase	unknown	unknown	gnl\|CDD\|181713

Protein	Function_ID	Function_description	E-value
NC_011283.1\|WP_012542481.1\|4003021_4004110_+\|oxidoreductase	gnl\|CDD\|182570	PRK10586, PRK10586, putative oxidoreductase; Provisional.	0
NC_011283.1\|WP_187148210.1\|3990597_3991548_+\|substrate-binding-domain-containing-protein	gnl\|CDD\|380501	cd06278, PBP1_LacI-like, ligand-binding domain of uncharacterized DNA-binding regulatory proteins that are members of the LacI-GalR family of bacterial transcription repressors. This group includes the ligand-binding domain of uncharacterized DNA-binding regulatory proteins that are members of the LacI-GalR family of bacterial transcription repressors. The LacI-GalR family repressors are composed of two functional domains: an N-terminal HTH (helix-turn-helix) domain, which is responsible for the DNA-binding specificity, and a C-terminal ligand-binding domain, which is homologous to the sugar-binding domain of ABC-type transport systems that contain the type 1 periplasmic binding protein-like fold. As also observed in the periplasmic binding proteins, the C-terminal domain of the bacterial transcription repressor undergoes a conformational change upon ligand binding which in turn changes the DNA binding affinity of the repressor.	6.22983e-92
NC_011283.1\|WP_008805590.1\|4006062_4008168_-\|carbon-starvation-protein-CstA	gnl\|CDD\|184976	PRK15015, PRK15015, carbon starvation protein CstA.	0
NC_011283.1\|WP_008805596.1\|3999275_4000340_-\|sugar-ABC-transporter-substrate-binding-protein	gnl\|CDD\|380528	cd06305, PBP1_methylthioribose_binding-like, similar to methylthioribose-binding protein of ABC-type transport systems that belong to a family of pentose/hexose sugar-binding proteins of the type 1 periplasmic binding protein (PBP1) superfamily. Proteins similar to methylthioribose-binding protein of ABC-type transport systems that belong to a family of pentose/hexose sugar-binding proteins of the type 1 periplasmic binding protein (PBP1) superfamily, which consists of two alpha/beta globular domains connected by a three-stranded hinge. This Venus flytrap-like domain undergoes transition from an open to a closed conformational state upon ligand binding. The sugar-binding domain of the periplasmic proteins in this group is also homologous to the ligand-binding domain of eukaryotic receptors such as metabotropic glutamate receptor (mGluR), DNA-binding transcriptional repressors such as LacI and GalR.	4.03307e-122
NC_011283.1\|WP_008805607.1\|3985662_3986271_-\|methylthioribulose-1-phosphate-dehydratase	gnl\|CDD\|236415	PRK09220, PRK09220, methylthioribulose 1-phosphate dehydratase.	1.57474e-138
NC_011283.1\|WP_012542480.1\|4001355_4002858_-\|sugar-ABC-transporter-ATP-binding-protein	gnl\|CDD\|224053	COG1129, MglA, ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism].	0
NC_011283.1\|WP_012542478.1\|3997930_3999172_-\|LVIVD-repeat-containing-protein	gnl\|CDD\|227601	COG5276, COG5276, Uncharacterized conserved protein [Function unknown].	4.26708e-149
NC_011283.1\|WP_012542474.1\|3986722_3987985_+\|cytosine-permease	gnl\|CDD\|236821	PRK11017, codB, cytosine permease; Provisional.	0
NC_011283.1\|WP_012542475.1\|3987981_3989217_+\|PucR-family-transcriptional-regulator-ligand-binding-domain-containing-protein	gnl\|CDD\|377939	pfam07905, PucR, Purine catabolism regulatory protein-like family. The bacterial proteins found in this family are similar to the purine catabolism regulatory protein expressed by Bacillus subtilis (PucR). PucR is thought to be a transcriptional activator involved in the induction of the purine degradation pathway, and may contain a LysR-like DNA-binding domain. It is similar to LysR-type regulators in that it represses its own expression. The other members of this family are also annotated as being putative regulatory proteins.	1.78324e-33
NC_011283.1\|WP_012542482.1\|4005371_4005776_+\|helix-turn-helix-transcriptional-regulator	gnl\|CDD\|238045	cd00093, HTH_XRE, Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators.	5.85373e-10
NC_011283.1\|WP_008805601.1\|3992589_3993948_+\|MFS-transporter	gnl\|CDD\|340870	cd17312, MFS_OPA_SLC37, Organophosphate:Pi antiporter/Solute Carrier family 37 of the Major Facilitator Superfamily of transporters. Organophosphate:Pi antiporters (OPA) are integral membrane proteins responsible for the transport of specific organophosphates or sugar phosphates across biological membranes with the simultaneous translocation of inorganic phosphate into the opposite direction. The OPA family is also called solute carrier family 37 (SLC37) in vertebrates. Members include glucose-6-phosphate (Glc6P) transporter (also called translocase or exchanger), glycerol-3-phosphate permease, 2-phosphonopropionate transporter, phosphoglycerate transporter, as well as membrane sensor protein UhpC from Escherichia coli. UhpC is both a sensor and a transport protein; it recognizes external Glc6P and induces transport by UhpT, and it can also transport Glc6P. Vertebrates contain four SLC37 or sugar-phosphate exchange (SPX) proteins: SLC37A1 (SPX1), SLC37A2 (SPX2), SLC37A3 (SPX3), and SLC37AA4 (SPX4). The OPA/SLC37 family belongs to the Major Facilitator Superfamily (MFS) of membrane transport proteins, which are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	8.48585e-128
NC_011283.1\|WP_012068432.1\|4004167_4004911_+\|3-oxoacyl-ACP-reductase-FabG	gnl\|CDD\|235500	PRK05557, fabG, 3-ketoacyl-(acyl-carrier-protein) reductase; Validated.	8.6298e-87
NC_011283.1\|WP_008805600.1\|3993974_3995243_+\|histidine-phosphatase-family-protein	gnl\|CDD\|366031	pfam00328, His_Phos_2, Histidine phosphatase superfamily (branch 2). The histidine phosphatase superfamily is so named because catalysis centers on a conserved His residue that is transiently phosphorylated during the catalytic cycle. Other conserved residues contribute to a 'phosphate pocket' and interact with the phospho group of substrate before, during and after its transfer to the His residue. Structure and sequence analyses show that different families contribute different additional residues to the 'phosphate pocket' and, more surprisingly, differ in the position, in sequence and in three dimensions, of a catalytically essential acidic residue. The superfamily may be divided into two main branches.The smaller branch 2 contains predominantly eukaryotic proteins. The catalytic functions in members include phytase, glucose-1-phosphatase and multiple inositol polyphosphate phosphatase. The in vivo roles of the mammalian acid phosphatases in branch 2 are not fully understood, although activity against lysophosphatidic acid and tyrosine-phosphorylated proteins has been demonstrated.	3.61435e-59
NC_011283.1\|WP_002893903.1\|4005772_4005970_-\|YbdD/YjiX-family-protein	gnl\|CDD\|225434	COG2879, COG2879, Uncharacterized small protein [Function unknown].	1.33159e-37
NC_011283.1\|WP_008805599.1\|3995303_3996332_-\|S-methyl-5-thioribose-1-phosphate-isomerase	gnl\|CDD\|273112	TIGR00512, methylthioribose-1-phosphate_isomerase_predicted, S-methyl-5-thioribose-1-phosphate isomerase. The delineation of this family was based in part on a discussion and neighbor-joining phylogenetic study, by Kyrpides and Woese, of archaeal and other proteins homologous to the alpha, beta, and delta subunits of eukaryotic initiation factor 2B (eIF-2B), a five-subunit molecule that catalyzes GTP recycling for eIF-2. This clade is now recognized to include the methionine salvage pathway enzyme MtnA. [Amino acid biosynthesis, Aspartate family].	4.76721e-150
NC_011283.1\|WP_012542477.1\|3996433_3997633_+\|S-methyl-5-thioribose-kinase	gnl\|CDD\|236561	PRK09550, mtnK, methylthioribose kinase; Reviewed.	0
NC_011283.1\|WP_008805592.1\|4005094_4005397_+\|type-II-toxin-antitoxin-system-RelE/ParE-family-toxin	gnl\|CDD\|224937	COG2026, RelE, Cytotoxic translational repressor of toxin-antitoxin stability system [Translation, ribosomal structure and biogenesis / Cell division and chromosome partitioning].	1.10031e-09
NC_011283.1\|WP_012542479.1\|4000360_4001359_-\|ABC-transporter-permease	gnl\|CDD\|224093	COG1172, AraH, Ribose/xylose/arabinose/galactoside ABC-type transport systems, permease components [Carbohydrate transport and metabolism].	2.08436e-69
NC_011283.1\|WP_008805602.1\|3991669_3992479_+\|inositol-monophosphatase	gnl\|CDD\|223559	COG0483, SuhB, Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family [Carbohydrate transport and metabolism].	8.1417e-72
NC_011283.1\|WP_008805604.1\|3989213_3990452_+\|cytosine-deaminase	gnl\|CDD\|181713	PRK09230, PRK09230, cytosine deaminase; Provisional.	0

>NC_011283.1|WP_012542477.1|3996433_3997633_+|S-methyl-5-thioribose-kinase
MSQYHTFTAHDAVAYAQQFAGIDNPSELVSAQEVGDGNLNLVFKVFDRQGVSRAIVKQALPYVRCVGESWPLTLDRARLEAQTLVAHYQHSPQHTVKIHHFDPELAVMVMEDLSDHRIWRGELIANVYYPQAARQLGDYLAQVLFHTSDFYLHPHEKKAQVAQFSNPAMCEITEDLFFNDPYQIHERNNYPAELETDVAALRDDAQLKLAVAALKHRFFAHAEALLHGDIHSGSIFVAEGSLKAIDAEFGYFGPIGFDIGTAIGNLLLNYCGLPGQLGIRDAAAAREQRLNDIHQLWTTFAERFQALAAEKTRDAALAYPGYASAFLKKVWADAVGFCGSELIRRSVGLSHVADIDTIQDDAMRHECLRHAITLGKALIVLAERIDSVDELLARVRQYS
>NC_011283.1|WP_008805599.1|3995303_3996332_-|S-methyl-5-thioribose-1-phosphate-isomerase
MQTLQTTSLRVSENQLFILDQQALPQEKRWLAADNVALLVDHIHALRVRGAPLIGLSASLLLALLAQRGLNRDALQQALETLRAARPTAVNLMNNLDRMKQALAREDYPQALEAEALRLVEEDKQLCDRIAEAGSALVKPGSRLLTHCNTGGLATAGVGTALGVIALAHRQGKVANVWVDETRPLLQGGRLTAWELGELGVPYQLITDSMAASLMAQGQVDAVWVGADRIAANGDVANKIGTYSLAVLAHYHQIPFYVAAPQTTLDRYCPNGAAIPIEQRAAAEVTGVAGSFGAVQWAPMGAAVYNPAFDVTPAGLVSGWVLDSGVVTPAQVAAGAFAPDNG
>NC_011283.1|WP_008805600.1|3993974_3995243_+|histidine-phosphatase-family-protein
MMPARHQGLLRLFIACALPLLALQSAAAADWQLEKVVELSRHGIRPPTAGNREAIEAATGRPWTEWTTHDGELTGHGYAAVVNKGREEGQHYRQLGLLQAGCPTAESIYVRASPLQRTRATAQALVDGAFPGCGVAIHYVSGDADPLFQTDKFAATQTDPARQLAAVKEKAGDLAQRRQALAPAIQLLQQAVCQADKPCPIFDTPWQVEQSKSGKTTISGLSVMANMVETLRLGWSENLPLSQLAWGKITQARQITALLPLLTENYDLSNDVLYTAQKRGSVLLNAMLDGVKPEANPNVRWLLLVAHDTNIAMVRTLMNFSWQLPGYSRGNIPPGSSLVLERWRNAKSGERYLRVYFQAQGLDDLRRLQTPDAQHPMLRQEWRQPGCRQTDVGTLCPFQAAITALGQRIDRSSAPAVAMVLP
>NC_011283.1|WP_008805601.1|3992589_3993948_+|MFS-transporter
MSGIIAFFRASPPKAGAAFDEQRFRRVRWQTFIAMTLAYVTFYVCRLSFTVAKSALVDLGITPTELGMIGSTLFFSYAIGKLVNGFIADHANVVRYMSLGLLLSAGMNLMMGMTTNALLLAIFWGINGWAQSMGVGPCAVSLARWYGVKERGTFYGIWSTAHNIGEAVTYMVIAAVIAGFGWQMGYLSTAALGAAGVVLLVLFMHDSPQSSGFPSINVIRDEPQEEAEARGSVFKNQLLALRNPALWTLALASAFMYIDRYAVNSWGIFFLEQDKAYSTLEASGIIGVNAIAGIAGTIIAGMLSDRFFPRNRSVMAGFISLLNTAGFALMLWSPHNYYTDILAMIIFGATIGALTCFLGGLIAVDISSRKAAGAALGTIGIASYAGAGLGEFLTGIIIDKTAILENGKTLYDFSTLALFWVGTGLGSALLCFTTAAIVARRHAVERQTSFSS
>NC_011283.1|WP_008805602.1|3991669_3992479_+|inositol-monophosphatase
MQSQESEALQARYRLACELAKAGAELAFEYYQQREALTVDHKGNDLQDVVSVADKRVEAFVKQRIQSAFPQDGFLGEESGTRLPDARILWVVDPIDGTSCFLNGLHTWCLSLAIVADGEPVIGVVYDPNHRELFHALRGHGAWLNDAPIRPHPATTVKEGVMGVGTSHRVTPADFLPFLQALLSDGGMFIRNGSGALMSAWAAAGRLIGYYEPHMNPWDALPGLVLMREAGGASNDFLAQEGIQRGNPLLLASQTLYPQLKKMIPQPLH
>NC_011283.1|WP_187148210.1|3990597_3991548_+|substrate-binding-domain-containing-protein
MARLAGVSRSAVSRTFTPGASVSEKTRQKVLSAAEALGYQVNIIARTMITGSSNFIGIVTAGFDNPFRSKLLAPLVHQLALNGFMPLLMNADDPQQLAPSLKQLLSYHVAGVIITSGAPPLSLAEEYLVRKIPVTLINRHADLAGCDRVCSDNAQGAKLVADLFSRRGWQQVGFIGENRENFSTRQRYDAFIARTSGMAVSSRFCDGGGYQAGSQAARELVAENPGVQALFCATDMLALGALDGLRDAPAPLPAIVGFDDIPQADWQPYQLTTVQQNTALLAHHAVDLLMTRIARFSLPSRHREVPVKLIIRHSAK
>NC_011283.1|WP_008805604.1|3989213_3990452_+|cytosine-deaminase
MKIINARLRRQEALFTLDLQDGMIHRISAQAAMQSADAGDIDAQGRLAIPPFVEPHIHLDATLTAGEPEWNRSGTLFEGITRWSQRKASITPEDTRQRALKTIGMLRDFGVQHVRTHVDVTDPSLAALKALLAVKQEAADLIDLQIVAFPQEGIESYPDGRGLMTRAIEMGADVVGGIPHYENTRDKGVSSVMFLMDLAQRYGRLVDVHCDEIDDPQSRFLEVLAEEARVRGMGAQVTASHTCAMGSYDNAYCSKLFRLLKASGINFISCPTESIHLQGRFDSWPKRRGVTRVAELDRAGINVCFAQDSIQDPWYPLGNGNILRILDAGLHICHMLGYDDLQRCLDFVTDNSARALCLGDNYGLAEGRPANLLILDAENDYEAVRRQARVLTSIRHGKVILQREVEHIRYPA
>NC_011283.1|WP_012542475.1|3987981_3989217_+|PucR-family-transcriptional-regulator-ligand-binding-domain-containing-protein
MSLTVSELLALEGLSALRLRAGKQGLQRAVRWYYVAENEHIAEWIMGGELVFITGINHPRDEANLIQLLMEGKQRGIAGMVILTGEAYIHAIPATLIALADELGIPLIEQPYLLKMVIVTERIGTALVRSENALQSQRDILMQLVTGDYPDLQMLHQRALHQQLDFTRPLRLAALRLEGLSRLFRQFPPEQAEAWLLQAHRSVRQQLQQQLNQQGNPFPLLERSNMFLFLLPDEEGEGFQQKKWLQQWLQALADGEEGLSLLCGLSAPVRQLQGYPRALSQARQALDLCDTLRPTQRISDYQQLGFIKLLSAVSDPALLNDFMHDTLGCLIEPGRKAPWLLLETLETLLQENGNVVRAADRLGLHRNTLHQRIQRIEKLTGYPVSHPQFHLNASVALVIWRLSQNHLQDPP
>NC_011283.1|WP_012542474.1|3986722_3987985_+|cytosine-permease
MSNSNDFPLVEAPAAGRKGVFSIAMVLFSFTFFTGTMFAGGKLGVSFSIVNLLWIAVIGNALLALYAASLGWIAARSGLNTVLMGRFCFGEIGSKLADFILGFAELGWYAWGTATVAISLVKILALPEALTQPLMVLFGILFCVTALVGYKGLDALSRLSVPLMFVLLMVSMYLALHHAGGWQAMTHIAPSDTMTWSAAITMVFGTFASGATQATNWTRLANSSRTAILASMGSFLIGNGLMIVAGAWCAIVYQQADIVEVLILQGLSVAAVIMLCLNLLTIQGPTIYNVSAAACHLLRSERRRTLTLAAAGVGIVLAIGGMYEMLIPFLVLLGSIIPPIGGVILADYWFARGGRYPLLQNARLPRFNWLGLGAYAAGAVVAYLSPWIAPLVGITVSALVYIVLSLLSKRQPAAVAEQEP
>NC_011283.1|WP_008805607.1|3985662_3986271_-|methylthioribulose-1-phosphate-dehydratase
MWQERLAQLVTTCHWIGAKGWAPATGGNMSVRQDDTWCWLSESGRDKGSLTTEDFLQVEIATNQAPSGRKPSAETGLHTLVYRLFPEANVVLHVHTVNATVLSRIEKSDTLALQGYEMQKTLSGQHSHLDTVPVAIFDNDQDIDALAARIADYAQTRPLRYGFLLRGHGLTCWGKDIQEARRQLEGLEFLFECELMRRRYEP
>NC_011283.1|WP_012542478.1|3997930_3999172_-|LVIVD-repeat-containing-protein
MSVLPSPEYSRNMRLIGHSDQGGRPDGVQLMVHRGFAYIGHMVSQGFSVVDVRDPTRPTTVNYIAAPPGTWNVHLQAHDDLLLVINARDLFADARFADEKVYYTRSVGDTVSDVQDKGWSAGLRIFDISTPAQPREISFLSLNGIGIHRIWYVGGRWAYVSALIDGFTDYIFLTIDLADPRKPEVAGRWWLPGMHQAGGETPDWPQGKRYALHHAIIAGDTAYGSWRDGGLTLLDVKDRTQPTLISHRNWTPPFGGGTHTALPLPDRDLLVVLDEAVLDNQEDGEKLIWLFDIREPANPVSISTFPQPDEIDYVAKGAHFGPHNLHENRPGSFVSSTLIFATYQNAGVRAYDISNPYRPLETGALVPAAPKTMMDTRPGRPQVIQSCDVFVDAQGIIYSTDYNGGLSVIEYLG
>NC_011283.1|WP_008805596.1|3999275_4000340_-|sugar-ABC-transporter-substrate-binding-protein
MKKIALSLMTLGLLQSTAALATAPTPVPAAIAEHSGPIRIAVIRNLGSDDNTTQFVSGALQEGKKLGFKISTFLSNGDDAKFQDFVNQAISQKYDGIILSQGRDPYSTALVKKAVDAGIKVAVFDTAVSGEIPGVTVSQQDDASLTELSFGQLVKDFNGKANIVKLWVAGFPPMERRQAAYQTLLKQNPGIKELESIGAVSSDVQGDTANKVGAILAKYPKGKIDAIWGTWDAFSQGAYKALKENGRTEIKLYSIDISNQDLQLMREAGSPWKVSVAVDPKLIGATNVRLIANKIAGEPTPATYDFKAAAIPQALLAAQPGAVNVASLGKIIPGWGQTEDFIAPWFATLEAKNK
>NC_011283.1|WP_012542479.1|4000360_4001359_-|ABC-transporter-permease
MSKALAVNTTVSGRQRFFDFLYKWGMLLTVVLLVAVFGLASDNFLDPFNIINILRSIAIVTVIAIGVSISLTIGGFDLSVGSTASLANALVISLFVWHGLGTTEAILITLALCTLVGLFNAFLIVVLRIPDMLATLASLFVIQGVAMTYSYGGSITENMVLPSGEMAEGTIPAGFGALGQVPTIVIIMLVVTLVAQLALSFTTHGRRMYAIGGNPEAARLSGLRITRYKVAAYVIASLLAGLGGILLASRIGSSQVNAGGGYLMDAVAAAWIGFSLAGSGKPNALGTLVGAVILGVLSNGLVMLSVPYYAMDIIKGLVLAGALALTYFQRRT
>NC_011283.1|WP_012542480.1|4001355_4002858_-|sugar-ABC-transporter-ATP-binding-protein
MSANRLEMHNISLAFSGFQALNKVDFTLHGGSVHALTGANGAGKSTLMAVLCGTHAHYQGEVTINDQPVTIRSPRDAKQLGIHLVQQEVDVALVPGLSIAENIMLDRLAEPGMAFRWSRVRQLAREALAQLDVALDVRRSIDSCTLAEKQQILLARALSHHCRFLILDEPTAPLDQHESERLFAVVRRLQQQGIGVVFISHRIHELKAICDTLTVLRDGRLIESGPMAPLSGEQIVEKMLGHELSDIFPPPRPPHGEEVLLQIDGLHDEALLQDISLRLRKGEILGIAGLAGAGKTELCKALFGASKSRVQRGELNGQPWRPRDPADSVGRGLALVPEERRKEGIFIEEPIAMNLAVSADNSFSRWSLFGHRQAWRWAEEVIARLGVRATGPGQMLRRLSGGNQQKVAIGKWLRSHANVLIFDEPTKGVDVKAKTDLFMLIDGLAREGKGVIYASGEFAELVGLCDRICVLWDGRIVAEIPGAEAREETLLYYSTGGAAA
>NC_011283.1|WP_012542481.1|4003021_4004110_+|oxidoreductase
MSNSDIRVVPGPANYFSHPGSLERLSDFFSADQLSRAVWVYGERALAGAEPFLPAAFHLPEAKKIRFTGHCSERDVAALVQASGDDRAVVIGVGGGALLDSAKVLARRLGVPLVAIPTIAATCAAWTPLSVWYSDAGQALNFEIFDDANFLVLVEPRIILNAPAEYLLAGIGDTLAKWYEAVVLAPQPEALPLTVRLGINGALAIRDVLLASSETALADQRRGDLTQAFRDVVEAIIAGGGMVGGLGERYTRVAAAHAVHNGLTVLPQTDKFLHGTKVAYGILVQSALLAQDDVLAQLVQAYQRFNLPTTLAALEVDINNRTELDRVIAHTLRPGESIHYLPVTLTPEVLRAAFEKVEYFSR
>NC_011283.1|WP_012068432.1|4004167_4004911_+|3-oxoacyl-ACP-reductase-FabG
MQIDLTGKKALVTGASRGLGRAIALSLARAGADVVITYEKSADKAQAVADEIKALGRHGEAVQADSASAQAIQEAVTHAARSLGGLDILVNNAGIARGGPLESMTLADIDALINVNIRGVVIATQEALVHMADGGRIINIGSCLANRVAMPGIAVYAMTKSALNALTRGLARDLGPRGITVNLVHPGPTNSDMNPEDGEQAEAQRQMIAVGHYGQPEDIAAAVTFLASPAAGQISGTGLDVDGGLNA
>NC_011283.1|WP_008805592.1|4005094_4005397_+|type-II-toxin-antitoxin-system-RelE/ParE-family-toxin
MKIVWSKTADKQFSKIDNRYKSRIKSRLEKMDDKASPISDIKKLSSPENHYRLRLGDYRVIYTFGDPPGDTCYVVAVKRRTTTTYLHEEDTEYDYSVHQG
>NC_011283.1|WP_012542482.1|4005371_4005776_+|helix-turn-helix-transcriptional-regulator
MTIQYIKDEEGKDQYVVIPYSDYFRMRLALLEYDDEDESEWEDIPYESDIYDNVTLPGEVCDVMHKENVSLQAAWRILRGLSQQEVAAKLGISQSAVSQLEALDSRPQKRTREKLAAIYGCTQEQISLYLPKEG
>NC_011283.1|WP_002893903.1|4005772_4005970_-|YbdD/YjiX-family-protein
MFDTLSKAGKYLGQAAKMMIGVPDYDNYVEHMRITHPDQTPMTYEEFFRERQDARYGGKGGAKCC
>NC_011283.1|WP_008805590.1|4006062_4008168_-|carbon-starvation-protein-CstA
MNNSGKYLIWTLLSVIGAFALGYIALNRGEQINALWIVVAAVCVYLIAYRFYGLYIAKTVLGVDPTRMTPAVRHNDGLDYVPTDKKVLFGHHFAAIAGAGPLVGPVLAAQMGYLPGMIWILAGVVLAGAVQDFMVLFVSTRRDGRSLGELVKEEMGPTAGVLALVACFMIMVIILAVLAMIVVKALTHSPWGTYTVAFTIPLAIFMGIYIRYLRPGRIGEVSVIGLVMLVFAIISGGWVAESPTWAPWFDYTGVQLTWILVGYGFVAAVLPVWLLLAPRDYLSTFLKIGTIVGLAIGILIMRPTLTMPALTKFVDGTGPVWSGNLFPFLFITIACGAVSGFHALISSGTTPKMLANEGQACFIGYGGMLMESFVAIMALVAACIIDPGVYFAMNSPMAVLAPAGTTDVVASAAQVVSGWGFSITPDTLHQIASEVGEQSIISRAGGAPTLAVGMAYILHGSLGGLMDVSFWYHFAILFEALFILTAVDAGTRAARFMLQDLLGVISPGLKKTSSLPANLLATALCVLAWGYFLHQGVVDPLGGINTLWPLFGIANQMLAGMALMLCAVVLFKMKRQRYAWVALLPTSWLLICTLTAGWQKSFSPDTKVGFLAIANKFQAMIDSGNIPPQYTESQLAQLVFNNRLDAGLTIFFMIVVVVLALFSIKTALAALKEDKPTAKETPYQAMPADAQTITAQAKRAH

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NC_011283_2	2.2\|2316685\|30\|NC_011283\|CRISPRCasFinder	2316685-2316714	30	MN276049	Acinetobacter phage BS46, complete genome	89443-89472	8	0.733

1. spacer 2.2|2316685|30|NC_011283|CRISPRCasFinder matches to MN276049 (Acinetobacter phage BS46, complete genome) position: , mismatch: 8, identity: 0.733

aaaaagaaaaactctccggttccctgttcg	CRISPR spacer
agggttaaaaactctccacttccctgttct	Protospacer
*...  ***********. **********

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

1664799 : 1671727

Planktothrix_phage(33.33%)

tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_041165424.1\|1664799_1665663_+	ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	1.7e-09	27.0
WP_012541061.1\|1665673_1666447_+	ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	7.8e-27	37.2
WP_008804075.1\|1666686_1667583_-	lipid kinase YegS	A0A1V0SBJ0	Catovirus	3.6e-15	29.8
WP_008804076.1\|1667825_1669187_-\|tRNA	tRNA 5-hydroxyuridine modification protein YegQ	Q6DW11	Phage_TP	1.0e-207	94.8
WP_004201558.1\|1669505_1670228_-	two-component system response regulator BaeR	W8CYM9	Bacillus_phage	8.3e-31	33.2
WP_012541063.1\|1670224_1671727_-	two-component system sensor histidine kinase BaeS	W8CYF6	Bacillus_phage	8.6e-30	28.3

DBSCAN-SWA_2

1834118 : 1880735

Catovirus(28.57%)

transposase,tRNA,integrase

attL 1844202:1844217|attR 1882899:1882914

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_012541153.1\|1834118_1835135_-\|integrase	tyrosine-type recombinase/integrase	NA	NA	NA	NA
WP_012541154.1\|1835127_1836054_-\|integrase	tyrosine-type recombinase/integrase	NA	NA	NA	NA
WP_012541155.1\|1836050_1836998_-\|integrase	tyrosine-type recombinase/integrase	NA	NA	NA	NA
WP_012541156.1\|1837136_1838030_-	site-specific DNA-methyltransferase	S4TR98	Salmonella_phage	1.6e-52	37.8
WP_012541157.1\|1838022_1838826_-	hypothetical protein	NA	NA	NA	NA
WP_012541158.1\|1838834_1840571_-	type IV secretory system conjugative DNA transfer family protein	NA	NA	NA	NA
WP_012541159.1\|1841339_1841642_-	lipoprotein	NA	NA	NA	NA
WP_012541160.1\|1841702_1842722_-	P-type DNA transfer ATPase VirB11	NA	NA	NA	NA
WP_012541161.1\|1842711_1844019_-	TrbI/VirB10 family protein	NA	NA	NA	NA
WP_041165339.1\|1844015_1844903_-	P-type conjugative transfer protein VirB9	NA	NA	NA	NA
1844202:1844217	attL	NA	NA	NA	NA
WP_012541163.1\|1844902_1845586_-	type IV secretion system protein	NA	NA	NA	NA
WP_012541164.1\|1845578_1845719_-	hypothetical protein	NA	NA	NA	NA
WP_012541165.1\|1845808_1846828_-	type IV secretion system protein	NA	NA	NA	NA
WP_012541166.1\|1846899_1847175_-	EexN family lipoprotein	NA	NA	NA	NA
WP_012541167.1\|1847186_1847915_-	type IV secretion system protein	NA	NA	NA	NA
WP_012541168.1\|1847937_1850685_-	VirB4 family type IV secretion/conjugal transfer ATPase	NA	NA	NA	NA
WP_020078412.1\|1850696_1850975_-	TrbC/VirB2 family protein	NA	NA	NA	NA
WP_012541170.1\|1850971_1851616_-	lytic transglycosylase domain-containing protein	NA	NA	NA	NA
WP_012541171.1\|1851687_1851909_-	hypothetical protein	NA	NA	NA	NA
WP_012541172.1\|1852303_1852513_-	TraR/DksA family transcriptional regulator	NA	NA	NA	NA
WP_012541173.1\|1852502_1853090_-	DUF2857 domain-containing protein	NA	NA	NA	NA
WP_041165340.1\|1853143_1853338_-	AlpA family transcriptional regulator	A0A1V0E8E5	Vibrio_phage	2.2e-07	42.1
WP_012541175.1\|1853685_1854603_-	hypothetical protein	NA	NA	NA	NA
WP_012541176.1\|1854862_1856047_-	MFS transporter	NA	NA	NA	NA
WP_012541177.1\|1856043_1857279_-	hypothetical protein	NA	NA	NA	NA
WP_012541178.1\|1857328_1858684_-	FAD-binding protein	NA	NA	NA	NA
WP_123809103.1\|1858729_1859638_-	hypothetical protein	NA	NA	NA	NA
WP_122490353.1\|1859790_1860513_-\|tRNA	alanyl-tRNA editing protein	NA	NA	NA	NA
WP_122490362.1\|1860584_1861634_-	aminotransferase class I/II-fold pyridoxal phosphate-dependent enzyme	A0A1X6WGT4	Pacmanvirus	1.4e-18	29.2
WP_012541182.1\|1861633_1863217_-	phenylalanine aminomutase (D-beta-phenylalanine forming)	A0A1V0S940	Catovirus	1.1e-67	31.2
WP_123809104.1\|1863243_1864245_-	TauD/TfdA family dioxygenase	NA	NA	NA	NA
WP_012541184.1\|1864669_1865920_-\|integrase	tyrosine-type recombinase/integrase	A7X7X0	Dichelobacter_phage	1.9e-54	35.1
WP_012541185.1\|1866563_1867484_+	LysR family transcriptional regulator	NA	NA	NA	NA
WP_012541186.1\|1867528_1869019_-	aldehyde dehydrogenase	NA	NA	NA	NA
WP_012541187.1\|1869011_1870658_-	GMC family oxidoreductase N-terminal domain-containing protein	A0A1V0S9J5	Catovirus	4.7e-53	30.5
WP_012541188.1\|1870672_1872076_-	cytosine permease	NA	NA	NA	NA
WP_012541189.1\|1872684_1873953_+	NAD(P)-binding domain-containing protein	NA	NA	NA	NA
WP_012541190.1\|1873962_1874388_+	RidA family protein	NA	NA	NA	NA
WP_012541191.1\|1874384_1875059_+	DUF1028 domain-containing protein	NA	NA	NA	NA
WP_012541192.1\|1875051_1876212_+	acetylornithine deacetylase	NA	NA	NA	NA
WP_123809086.1\|1877463_1877697_+	hypothetical protein	NA	NA	NA	NA
WP_077251701.1\|1878057_1878648_-\|transposase	transposase	NA	NA	NA	NA
WP_116403514.1\|1879167_1879392_+	SDR family oxidoreductase	NA	NA	NA	NA
WP_012541194.1\|1879466_1880735_-\|integrase	integrase arm-type DNA-binding domain-containing protein	A0A1B0VMI6	Pseudomonas_phage	5.7e-67	38.1
1882899:1882914	attR	NA	NA	NA	NA

DBSCAN-SWA_3

2059833 : 2123187

Bacillus_phage(16.67%)

protease,transposase,plate

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_008804320.1\|2059833_2060580_+\|protease	proteasome-type protease	NA	NA	NA	NA
WP_012541287.1\|2060641_2061727_-	sn-glycerol-3-phosphate ABC transporter ATP-binding protein UgpC	W8CYL7	Bacillus_phage	1.6e-14	31.4
WP_012541288.1\|2061713_2062676_-	carbohydrate kinase family protein	NA	NA	NA	NA
WP_032738925.1\|2062678_2063518_-	carbohydrate ABC transporter permease	NA	NA	NA	NA
WP_012541290.1\|2063507_2064416_-	sugar ABC transporter permease	NA	NA	NA	NA
WP_012541291.1\|2064425_2065670_-	extracellular solute-binding protein	NA	NA	NA	NA
WP_012541292.1\|2065884_2067093_+	ROK family transcriptional regulator	NA	NA	NA	NA
WP_008804327.1\|2067167_2068154_+	fatty acid desaturase	NA	NA	NA	NA
WP_012541293.1\|2068146_2068947_+	PhnD/SsuA/transferrin family substrate-binding protein	NA	NA	NA	NA
WP_041165346.1\|2068994_2070326_-	NtaA/DmoA family FMN-dependent monooxygenase	NA	NA	NA	NA
WP_012541295.1\|2070369_2071269_-	ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_004203269.1\|2071329_2071998_-	ABC transporter permease	NA	NA	NA	NA
WP_012541296.1\|2071997_2072627_-	ABC transporter permease subunit	NA	NA	NA	NA
WP_012541297.1\|2072619_2073708_-	ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	6.7e-24	35.1
WP_163595297.1\|2074145_2074286_-	hypothetical protein	NA	NA	NA	NA
WP_008804334.1\|2074465_2075404_+	transcriptional regulator TdcA	NA	NA	NA	NA
WP_012541298.1\|2075497_2076487_+	bifunctional threonine ammonia-lyase/L-serine ammonia-lyase TdcB	NA	NA	NA	NA
WP_004200322.1\|2076512_2077844_+	threonine/serine transporter TdcC	NA	NA	NA	NA
WP_012541299.1\|2077871_2079077_+	propionate kinase	NA	NA	NA	NA
WP_012541300.1\|2079105_2081400_+	formate C-acetyltransferase	A0A2P0VNR5	Tetraselmis_virus	1.4e-156	41.6
WP_004225356.1\|2081451_2081598_-	hypothetical protein	NA	NA	NA	NA
WP_162493310.1\|2081887_2082946_+	ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_008804338.1\|2083055_2083970_+	branched-chain amino acid ABC transporter permease	NA	NA	NA	NA
WP_012541302.1\|2083979_2085266_+	high-affinity branched-chain amino acid ABC transporter permease LivM	NA	NA	NA	NA
WP_004148803.1\|2085262_2086138_+	ATP-binding cassette domain-containing protein	W8CYL7	Bacillus_phage	9.5e-05	41.5
WP_012541303.1\|2086134_2086854_+	ABC transporter ATP-binding protein	A0A2H4PQG7	Staphylococcus_phage	8.6e-12	26.0
WP_008804342.1\|2086859_2087753_-	LysR family transcriptional regulator	NA	NA	NA	NA
WP_012541305.1\|2088036_2089680_+	phosphoenolpyruvate carboxykinase (ATP)	A0A2H4PQN1	Staphylococcus_phage	7.5e-136	50.4
WP_012541306.1\|2089729_2090206_-	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_012541307.1\|2090304_2091237_+	LysR family transcriptional regulator	NA	NA	NA	NA
WP_032432118.1\|2091542_2092838_+	MFS transporter	Q6JIH2	Burkholderia_virus	2.8e-61	36.2
WP_008804347.1\|2092849_2093659_+	substrate-binding domain-containing protein	NA	NA	NA	NA
WP_008804348.1\|2093633_2094533_-	LysR family transcriptional regulator	NA	NA	NA	NA
WP_012541308.1\|2094645_2095128_-	cold shock domain-containing protein	NA	NA	NA	NA
WP_012541309.1\|2095319_2096018_+	RluA family pseudouridine synthase	A0A2H4UV25	Bodo_saltans_virus	5.3e-06	27.2
WP_040968648.1\|2096043_2096583_-	DUF2058 domain-containing protein	NA	NA	NA	NA
WP_012541311.1\|2096951_2097641_+	D-galactonate utilization transcriptional regulator DgoR	NA	NA	NA	NA
WP_012541312.1\|2097637_2098555_+	2-dehydro-3-deoxygalactonokinase	NA	NA	NA	NA
WP_012541313.1\|2098499_2099117_+	2-dehydro-3-deoxy-6-phosphogalactonate aldolase	NA	NA	NA	NA
WP_012541314.1\|2099113_2100262_+	galactonate dehydratase	Q6A202	Oenococcus_phage	2.1e-52	34.2
WP_012541315.1\|2100356_2101670_+	MFS transporter	NA	NA	NA	NA
WP_012541316.1\|2101666_2102614_+	2-hydroxyacid dehydrogenase	NA	NA	NA	NA
WP_012541317.1\|2102671_2103001_-	gamma-glutamylcyclotransferase	NA	NA	NA	NA
WP_012541319.1\|2103630_2104971_+\|plate	type VI secretion system baseplate subunit TssK	NA	NA	NA	NA
WP_012541320.1\|2104967_2105621_+	DotU family type IV/VI secretion system protein	NA	NA	NA	NA
WP_012541321.1\|2105624_2107322_+	OmpA family protein	NA	NA	NA	NA
WP_012541324.1\|2107780_2110408_+	type VI secretion system tip protein VgrG	A0A2H4JCD4	uncultured_Caudovirales_phage	1.7e-17	29.9
WP_000654804.1\|2110946_2111915_+\|transposase	IS5-like element IS903B family transposase	A0A1B0VFY5	Salmonella_phage	1.0e-185	99.4
WP_123809090.1\|2111911_2113495_+	M23 family metallopeptidase	A0A2H4JIA8	uncultured_Caudovirales_phage	1.6e-58	33.8
WP_032733488.1\|2113946_2114351_+	hypothetical protein	NA	NA	NA	NA
WP_004899008.1\|2114376_2114634_+	PAAR domain-containing protein	NA	NA	NA	NA
WP_012541328.1\|2114638_2115850_+	hypothetical protein	NA	NA	NA	NA
WP_181446013.1\|2115864_2119281_+	type VI secretion protein VasK	NA	NA	NA	NA
WP_012541330.1\|2119414_2121178_+\|plate	type VI secretion system baseplate subunit TssF	NA	NA	NA	NA
WP_171004785.1\|2121207_2122224_+\|plate	type VI secretion system baseplate subunit TssG	NA	NA	NA	NA
WP_012541332.1\|2122204_2122741_+	type VI secretion system lipoprotein TssJ	NA	NA	NA	NA
WP_004152261.1\|2122743_2123187_+\|plate	type VI secretion system baseplate subunit TssE	NA	NA	NA	NA

DBSCAN-SWA_4

2828947 : 2839826

Escherichia_phage(87.5%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_012541788.1\|2828947_2832055_+	beta-galactosidase	L0N6M2	Herpes_simplex_virus	0.0e+00	59.4
WP_008804978.1\|2832109_2833375_+	MFS transporter	NA	NA	NA	NA
WP_012541789.1\|2833403_2834492_-	AAA family ATPase	A0A077SLJ9	Escherichia_phage	2.8e-208	98.6
WP_008804980.1\|2834578_2834839_-	hypothetical protein	A0A077SK33	Escherichia_phage	3.0e-39	95.3
WP_012541790.1\|2835133_2835994_+	class A beta-lactamase LEN-28	A0A077SL40	Escherichia_phage	8.7e-144	90.2
WP_008804982.1\|2836011_2836773_-	DeoR/GlpR transcriptional regulator	A0A077SK06	Escherichia_phage	2.1e-133	99.2
WP_008804983.1\|2837033_2837936_+	NAD(P)-dependent oxidoreductase	A0A077SLF7	Escherichia_phage	1.1e-157	98.7
WP_012541791.1\|2837947_2839213_+	four-carbon acid sugar kinase family protein	A0A077SLJ7	Escherichia_phage	8.4e-228	97.1
WP_012541792.1\|2839205_2839826_+	aldolase	A0A077SK32	Escherichia_phage	5.7e-113	98.1

DBSCAN-SWA_5

2851506 : 2856754

Escherichia_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_008804980.1\|2851506_2851767_-	hypothetical protein	A0A077SK33	Escherichia_phage	3.0e-39	95.3
WP_012541790.1\|2852061_2852922_+	class A beta-lactamase LEN-28	A0A077SL40	Escherichia_phage	8.7e-144	90.2
WP_008804982.1\|2852939_2853701_-	DeoR/GlpR transcriptional regulator	A0A077SK06	Escherichia_phage	2.1e-133	99.2
WP_008804983.1\|2853961_2854864_+	NAD(P)-dependent oxidoreductase	A0A077SLF7	Escherichia_phage	1.1e-157	98.7
WP_012541791.1\|2854875_2856141_+	four-carbon acid sugar kinase family protein	A0A077SLJ7	Escherichia_phage	8.4e-228	97.1
WP_012541792.1\|2856133_2856754_+	aldolase	A0A077SK32	Escherichia_phage	5.7e-113	98.1

DBSCAN-SWA_6

2878718 : 2902884

Enterobacteria_phage(31.25%)

holin,integrase,terminase,transposase,lysis

attL 2883441:2883454|attR 2890878:2890891

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_000654804.1\|2878718_2879687_-\|transposase	IS5-like element IS903B family transposase	A0A1B0VFY5	Salmonella_phage	1.0e-185	99.4
WP_041165367.1\|2880187_2880562_+	hypothetical protein	NA	NA	NA	NA
WP_012541815.1\|2881861_2882860_+\|integrase	site-specific integrase	NA	NA	NA	NA
2883441:2883454	attL	NA	NA	NA	NA
WP_050774490.1\|2883843_2885067_+\|integrase	tyrosine-type recombinase/integrase	NA	NA	NA	NA
WP_012541817.1\|2885159_2885678_-	hypothetical protein	NA	NA	NA	NA
WP_012541818.1\|2885690_2886545_-	WYL domain-containing protein	NA	NA	NA	NA
WP_012541819.1\|2886681_2887863_+	hypothetical protein	NA	NA	NA	NA
WP_012541820.1\|2887859_2890088_+	Mov34/MPN/PAD-1 family protein	NA	NA	NA	NA
WP_004179627.1\|2890262_2890682_-	translesion error-prone DNA polymerase V autoproteolytic subunit	A0A1W6JNS2	Morganella_phage	8.5e-36	58.3
WP_023289582.1\|2891243_2891414_+	DinI-like family protein	S5MQI1	Escherichia_phage	3.6e-17	74.5
2890878:2890891	attR	NA	NA	NA	NA
WP_050774492.1\|2891690_2892212_-	DUF1353 domain-containing protein	K4F6K2	Cronobacter_phage	2.9e-09	36.5
WP_012541824.1\|2892524_2893121_-	recombinase family protein	A0A286S1P7	Klebsiella_phage	6.5e-90	96.1
WP_012541826.1\|2895210_2895552_-	cell envelope integrity protein TolA	NA	NA	NA	NA
WP_041165445.1\|2895641_2895839_-	hypothetical protein	A0A286SGR9	Klebsiella_phage	7.5e-19	74.6
WP_077251711.1\|2896029_2896233_-\|terminase	terminase small subunit	I6PDJ6	Cronobacter_phage	8.3e-21	81.8
WP_123809092.1\|2896594_2897017_-	hypothetical protein	NA	NA	NA	NA
WP_012541829.1\|2897105_2897570_-\|lysis	lysis protein	Q76H63	Enterobacteria_phage	1.4e-52	70.1
WP_012541830.1\|2897566_2898046_-	glycoside hydrolase family 104 protein	A5VW81	Enterobacteria_phage	3.5e-70	81.8
WP_012541831.1\|2898029_2898353_-\|holin	phage holin, lambda family	G5DA93	Enterobacteria_phage	6.1e-42	80.4
WP_041165369.1\|2898562_2898856_-	hypothetical protein	NA	NA	NA	NA
WP_012541833.1\|2898946_2899633_+	hypothetical protein	NA	NA	NA	NA
WP_123809093.1\|2899827_2900076_-	hypothetical protein	NA	NA	NA	NA
WP_012541835.1\|2900232_2901030_-	antitermination protein	H6WRZ1	Salmonella_phage	2.0e-118	77.7
WP_012541836.1\|2901026_2901164_-	YlcG family protein	A0A0M5M7B2	Salmonella_phage	4.6e-07	67.6
WP_012541837.1\|2901160_2901517_-	RusA family crossover junction endodeoxyribonuclease	K7P6W0	Enterobacteria_phage	1.5e-41	63.6
WP_041165370.1\|2901513_2901810_-	DUF1364 domain-containing protein	A0A0U2KD41	Escherichia_phage	3.9e-35	70.8
WP_012541839.1\|2902018_2902615_-	DUF1367 family protein	K7PKS6	Enterobacteria_phage	1.5e-89	79.6
WP_012541840.1\|2902650_2902884_-	hypothetical protein	A0A0M4R5D9	Salmonella_phage	7.5e-18	57.1

DBSCAN-SWA_7

2906849 : 2914932

Cronobacter_phage(16.67%)

integrase

attL 2907165:2907177|attR 2913166:2913178

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_071822071.1\|2906849_2907182_+	hypothetical protein	I6PD68	Cronobacter_phage	7.2e-22	54.1
2907165:2907177	attL	NA	NA	NA	NA
WP_032436018.1\|2907189_2907429_+	DUF4060 family protein	M9P0E0	Enterobacteria_phage	2.5e-24	70.5
WP_012541846.1\|2907488_2907746_+	hypothetical protein	NA	NA	NA	NA
WP_012541847.1\|2907726_2908866_+\|integrase	phage integrase Arm DNA-binding domain-containing protein	Q77Z04	Phage_21	7.8e-92	47.6
WP_012541848.1\|2909015_2911061_-	peptidyl-dipeptidase Dcp	A0A1V0SIU1	Klosneuvirus	1.5e-16	19.8
WP_008805005.1\|2911191_2911941_+	bifunctional NADP-dependent 3-hydroxy acid dehydrogenase/3-hydroxypropionate dehydrogenase YdfG	NA	NA	NA	NA
WP_008805006.1\|2912032_2912719_+	GntR family transcriptional regulator	NA	NA	NA	NA
WP_008805007.1\|2912770_2913202_-	universal stress protein	A0A1W6JNV4	Morganella_phage	3.6e-21	40.0
2913166:2913178	attR	NA	NA	NA	NA
WP_012541849.1\|2913468_2914932_-	fructuronate reductase	H8ZJP8	Ostreococcus_tauri_virus	1.1e-42	30.2

DBSCAN-SWA_8

3190675 : 3202590

Salmonella_phage(20.0%)

integrase

attL 3183840:3183857|attR 3198071:3198088

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
3183840:3183857	attL	NA	NA	NA	NA
WP_187148206.1\|3190675_3191959_-	hypothetical protein	B5TAB2	Burkholderia_phage	5.2e-68	36.9
WP_012542036.1\|3193673_3194783_+	recombinase RecT	H6WRX0	Salmonella_phage	1.4e-181	85.4
WP_032423798.1\|3194826_3195441_+	hypothetical protein	M1F3E2	Salmonella_phage	1.0e-66	61.6
WP_012542038.1\|3195437_3195746_+	hypothetical protein	I6PD68	Cronobacter_phage	4.2e-24	56.9
WP_004892750.1\|3195753_3195993_+	DUF4060 family protein	M9P0E0	Enterobacteria_phage	8.0e-23	70.1
WP_012542039.1\|3196213_3197431_-\|integrase	site-specific integrase	K7PGY1	Enterobacteria_phage	3.3e-120	51.6
WP_008807805.1\|3197577_3198468_+	peptide ABC transporter permease SapC	NA	NA	NA	NA
3198071:3198088	attR	NA	NA	NA	NA
WP_008807804.1\|3198467_3199460_+	peptide ABC transporter ATP-binding protein SapD	G9BWD6	Planktothrix_phage	3.0e-07	27.2
WP_004140269.1\|3199461_3200271_+	peptide ABC transporter ATP-binding protein SapF	A0A2H4PQG7	Staphylococcus_phage	2.1e-14	28.9
WP_012542040.1\|3200299_3201799_-	histidine ammonia-lyase	A0A1V0S940	Catovirus	1.8e-59	33.6
WP_008807802.1\|3201795_3202590_-	ATP-binding cassette domain-containing protein	G9BWD6	Planktothrix_phage	6.6e-29	37.4

DBSCAN-SWA_9

3395475 : 3425549

Salmonella_phage(20.69%)

tail,portal,terminase,integrase

attL 3393159:3393172|attR 3425972:3425985

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
3393159:3393172	attL	NA	NA	NA	NA
WP_012542162.1\|3395475_3396225_-\|tail	phage minor tail protein L	K7PGX3	Enterobacteria_phage	2.6e-83	57.2
WP_012542163.1\|3396317_3396677_-	hypothetical protein	NA	NA	NA	NA
WP_012542164.1\|3396689_3397040_-\|tail	phage tail protein	Q6UAW6	Klebsiella_phage	3.4e-22	41.8
WP_012542166.1\|3398869_3400129_-\|portal	phage portal protein	Q6UAX8	Klebsiella_phage	2.8e-223	90.2
WP_017898992.1\|3400128_3400308_-	hypothetical protein	Q6UAX9	Klebsiella_phage	3.1e-11	57.6
WP_012542167.1\|3400301_3402023_-\|terminase	terminase large subunit	Q7Y413	Yersinia_phage	1.1e-190	57.4
WP_012542168.1\|3402022_3402457_-\|terminase	phage terminase small subunit P27 family	A0A1J0GV10	Halomonas_phage	9.4e-30	61.9
WP_012542169.1\|3402790_3403222_-	hypothetical protein	Q6UAS0	Klebsiella_phage	2.1e-42	62.7
WP_012542170.1\|3403221_3403542_-	hypothetical protein	NA	NA	NA	NA
WP_012542171.1\|3403493_3403856_-	HNH endonuclease	Q6UAS2	Klebsiella_phage	8.9e-58	83.3
WP_032414050.1\|3404183_3404381_+	hypothetical protein	H6WRV6	Salmonella_phage	1.1e-20	73.8
WP_181159912.1\|3404364_3404514_-	hypothetical protein	NA	NA	NA	NA
WP_012542173.1\|3405456_3405807_-	hypothetical protein	A0A0K2FIW3	Enterobacter_phage	3.5e-11	36.8
WP_032439908.1\|3405803_3406301_-	lysozyme	A0A1V0E5Q7	Salmonella_phage	9.0e-77	82.7
WP_023289178.1\|3406278_3406548_-	hypothetical protein	K7P6H9	Enterobacteria_phage	4.2e-36	85.9
WP_012542176.1\|3407285_3407693_-	type II toxin-antitoxin system HicB family antitoxin	F1C593	Cronobacter_phage	2.8e-52	78.8
WP_012542177.1\|3407740_3407917_-	type II toxin-antitoxin system HicA family toxin	A0A0R6PD93	Moraxella_phage	1.4e-08	56.4
WP_020803203.1\|3408277_3409435_+	DUF262 domain-containing protein	A0A0R6PJX3	Moraxella_phage	1.3e-57	36.1
WP_012542179.1\|3409436_3410126_+	hypothetical protein	NA	NA	NA	NA
WP_012542180.1\|3410091_3411135_-	DNA cytosine methyltransferase	A0A0R6PG08	Moraxella_phage	5.7e-97	52.1
WP_012542181.1\|3411224_3411569_-	antitermination protein	A0A0P0ZCW0	Stx2-converting_phage	1.3e-50	80.5
WP_012542182.1\|3411581_3412613_-	DUF968 domain-containing protein	S5MW46	Escherichia_phage	9.6e-97	49.9
WP_041165380.1\|3412812_3413205_-	DNA-binding protein	K7PHB4	Enterobacterial_phage	5.5e-13	38.6
WP_022065893.1\|3413245_3413503_-	hypothetical protein	H6WRY6	Salmonella_phage	5.4e-17	56.9
WP_012542186.1\|3413547_3413781_-	DinI family protein	K7PM44	Enterobacteria_phage	1.7e-25	71.1
WP_012542188.1\|3414219_3414909_+	YafY family transcriptional regulator	A0A1B0RXM1	Streptococcus_phage	1.3e-09	27.5
WP_012542189.1\|3414979_3415726_+	SDR family oxidoreductase	W8CYX9	Bacillus_phage	2.3e-07	31.6
WP_012542191.1\|3416049_3416277_+	DUF1737 domain-containing protein	NA	NA	NA	NA
WP_012542193.1\|3416723_3418487_-	EAL domain-containing protein	NA	NA	NA	NA
WP_041165381.1\|3418799_3419240_-	PerC family transcriptional regulator	NA	NA	NA	NA
WP_012542196.1\|3419253_3419718_-	replication protein	A0A0U2JGJ0	Escherichia_phage	1.7e-61	70.2
WP_012542197.1\|3419710_3420694_-	hypothetical protein	A0A0U2RT81	Escherichia_phage	3.6e-45	56.4
WP_012542198.1\|3420745_3421300_-	hypothetical protein	NA	NA	NA	NA
WP_012542199.1\|3421302_3421518_-	helix-turn-helix domain-containing protein	A0A0M4QX15	Salmonella_phage	2.0e-17	57.5
WP_012542200.1\|3421619_3422009_+	helix-turn-helix domain-containing protein	A0A0M4R5D1	Salmonella_phage	6.7e-35	60.2
WP_071822045.1\|3422354_3422669_-	hypothetical protein	NA	NA	NA	NA
WP_012542202.1\|3423058_3423253_+	DUF1482 family protein	NA	NA	NA	NA
WP_071822046.1\|3423864_3424143_+	3'-5' exoribonuclease	C6ZR35	Salmonella_phage	5.5e-23	64.9
WP_012542206.1\|3424195_3424441_+	excisionase	NA	NA	NA	NA
WP_012542207.1\|3424421_3425549_+\|integrase	phage integrase Arm DNA-binding domain-containing protein	O21925	Phage_21	9.7e-119	58.4
3425972:3425985	attR	NA	NA	NA	NA

DBSCAN-SWA_10

3683280 : 3692728

Brazilian_cedratvirus(16.67%)

protease,tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_012542330.1\|3683280_3685002_+	cysteine/glutathione ABC transporter ATP-binding protein/permease CydC	A0A2R8FG22	Brazilian_cedratvirus	4.5e-14	34.0
WP_008805841.1\|3685041_3685746_+\|tRNA	leucyl/phenylalanyl-tRNA--protein transferase	NA	NA	NA	NA
WP_001040187.1\|3686097_3686316_+	translation initiation factor IF-1	NA	NA	NA	NA
WP_012542332.1\|3686434_3688714_-\|protease	ATP-dependent Clp protease ATP-binding subunit ClpA	A0A223W0B1	Agrobacterium_phage	3.7e-165	42.0
WP_002896520.1\|3688744_3689062_-\|protease	ATP-dependent Clp protease adapter ClpS	A0A1B1IT64	uncultured_Mediterranean_phage	2.0e-13	45.7
WP_002896516.1\|3689387_3689609_+	cold shock-like protein CspD	A0A2H4N7Y6	Lake_Baikal_phage	1.3e-16	61.2
WP_012542333.1\|3689675_3691616_-	macrolide ABC transporter ATP-binding protein/permease MacB	G9BWD6	Planktothrix_phage	2.2e-38	41.0
WP_008805838.1\|3691612_3692728_-	macrolide transporter subunit MacA	A0A140XAI1	Dickeya_phage	1.3e-06	52.7

DBSCAN-SWA_11

4187276 : 4233273

Enterobacteria_phage(24.07%)

holin,tRNA,terminase,plate,head

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_012542580.1\|4187276_4187864_-	DUF2612 domain-containing protein	A0A077K9U8	Edwardsiella_phage	8.5e-34	42.9
WP_012542581.1\|4187856_4189089_-\|plate	baseplate J/gp47 family protein	A0A077KGW9	Edwardsiella_phage	8.7e-105	50.2
WP_001518114.1\|4189096_4189453_-	hypothetical protein	NA	NA	NA	NA
WP_041165393.1\|4190499_4190661_-	Arc family DNA-binding protein	I6S1K8	Salmonella_phage	3.6e-11	61.2
WP_012542583.1\|4190748_4191000_+	Arc family DNA-binding protein	E7C9U8	Salmonella_phage	3.4e-24	70.4
WP_012542584.1\|4191000_4191204_+	hypothetical protein	NA	NA	NA	NA
WP_101881437.1\|4191233_4191587_-	hypothetical protein	NA	NA	NA	NA
WP_012542586.1\|4191586_4192174_-	hypothetical protein	A1Z003	Burkholderia_virus	6.4e-05	23.6
WP_009308058.1\|4192175_4193030_-	hypothetical protein	A0A077KC17	Edwardsiella_phage	1.4e-29	30.1
WP_009308057.1\|4193026_4193332_-	hypothetical protein	A0A077K9U4	Edwardsiella_phage	4.7e-20	47.5
WP_012542587.1\|4193333_4194176_-	hypothetical protein	A0A077KGW3	Edwardsiella_phage	5.9e-28	31.8
WP_012542588.1\|4194179_4196105_-	lytic transglycosylase domain-containing protein	A0A0M4REK7	Salmonella_phage	4.5e-39	57.8
WP_041165394.1\|4196085_4196268_-	hypothetical protein	NA	NA	NA	NA
WP_012542590.1\|4196309_4196786_-	hypothetical protein	A0A068CGG2	Acinetobacter_phage	6.5e-08	31.1
WP_012542591.1\|4196847_4197291_-	hypothetical protein	NA	NA	NA	NA
WP_012542592.1\|4197290_4198772_-	DUF3383 domain-containing protein	Q2NPD0	Xanthomonas_phage	7.9e-60	34.6
WP_012542593.1\|4198775_4199327_-	hypothetical protein	NA	NA	NA	NA
WP_012542594.1\|4199308_4199677_-	hypothetical protein	Q6UJ26	Burkholderia_virus	2.8e-06	29.8
WP_012542595.1\|4199673_4200237_-	hypothetical protein	H9C0W2	Aeromonas_phage	3.7e-18	32.9
WP_012542596.1\|4200239_4200683_-	DUF4054 domain-containing protein	A0A068CGG9	Acinetobacter_phage	1.8e-12	40.3
WP_012542597.1\|4200682_4201009_-	hypothetical protein	H9C0V9	Aeromonas_phage	4.8e-10	43.4
WP_012542598.1\|4201010_4202048_-	DUF2184 domain-containing protein	A0A219YBB0	Aeromonas_phage	1.2e-83	49.7
WP_012542599.1\|4202047_4202530_-	hypothetical protein	A0A2R3UAX9	Myoviridae_environmental_samples	4.5e-33	58.5
WP_012542600.1\|4202531_4203698_-	DUF2213 domain-containing protein	A0A219YCD3	Aeromonas_phage	2.0e-58	37.6
WP_041165395.1\|4203701_4204400_-\|head	head morphogenesis protein	H9C0V1	Aeromonas_phage	2.5e-64	53.5
WP_012542602.1\|4204452_4205973_-	DUF1073 domain-containing protein	A0A2R3UAL5	Myoviridae_environmental_samples	6.1e-100	42.2
WP_009308026.1\|4205973_4207650_-\|terminase	phage terminase large subunit	H9C191	Pectobacterium_phage	7.9e-250	74.6
WP_012542603.1\|4207651_4208137_-	DUF2280 domain-containing protein	H9C190	Pectobacterium_phage	6.3e-67	78.9
WP_012542604.1\|4208167_4208803_-	hypothetical protein	I6S676	Salmonella_phage	2.3e-101	81.1
WP_071822056.1\|4208928_4209147_+	hypothetical protein	NA	NA	NA	NA
WP_012542607.1\|4209350_4209740_-	DUF2570 domain-containing protein	Q8SBD9	Shigella_phage	9.4e-21	43.7
WP_041165462.1\|4209736_4210234_-	lysozyme	K7P7Q3	Enterobacteria_phage	1.3e-78	84.2
WP_012542609.1\|4210211_4210481_-\|holin	holin	K7P6H9	Enterobacteria_phage	2.8e-32	78.3
WP_012542610.1\|4211272_4211773_-	late gene antiterminator protein	G8C7V7	Escherichia_phage	8.7e-88	92.1
WP_012542611.1\|4211769_4211910_-	YlcG family protein	NA	NA	NA	NA
WP_041165396.1\|4211906_4212104_-	Lar family restriction alleviation protein	M9NZE6	Enterobacteria_phage	1.5e-27	84.1
WP_012542612.1\|4212100_4212739_-	recombination protein NinG	H6WRY9	Salmonella_phage	1.6e-73	69.3
WP_012542613.1\|4212731_4213400_-	metallophosphoesterase	M9P0E4	Enterobacteria_phage	5.2e-104	77.9
WP_012542614.1\|4213396_4213564_-	NinE family protein	K7P7K0	Enterobacteria_phage	3.5e-09	62.5
WP_012542615.1\|4213544_4214012_-	recombination protein NinB	Q8VNP6	Enterobacteria_phage	1.7e-32	45.8
WP_012542616.1\|4214213_4214471_-	DNA polymerase III subunit theta	G8C7V1	Escherichia_phage	3.4e-27	77.9
WP_012542617.1\|4214516_4214747_-	hypothetical protein	NA	NA	NA	NA
WP_041165397.1\|4214785_4215091_-	hypothetical protein	Q7Y3Y0	Yersinia_phage	4.6e-15	44.4
WP_041165398.1\|4215083_4215959_-	DUF551 domain-containing protein	O64350	Escherichia_phage	5.8e-10	45.7
WP_012542622.1\|4216300_4216966_-	ead/Ea22-like family protein	A0A075B8K3	Enterobacteria_phage	1.8e-32	46.6
WP_012542623.1\|4216958_4217354_-	hypothetical protein	G8C7U4	Escherichia_phage	1.7e-57	78.9
WP_041165400.1\|4217350_4217554_-	hypothetical protein	A0A2P1JU43	Erwinia_phage	1.4e-07	48.2
WP_012542625.1\|4217547_4218081_-	hypothetical protein	U6C6B8	Ralstonia_phage	8.1e-07	47.9
WP_012542626.1\|4218077_4218371_-	protein ren	O48423	Enterobacteria_phage	2.5e-26	65.6
WP_012542627.1\|4218367_4219237_-	ATP-binding protein	K7PLU3	Enterobacteria_phage	4.0e-96	70.1
WP_012542628.1\|4219221_4220076_-	replication protein	K7PGT1	Enterobacteria_phage	7.5e-63	55.4
WP_012542630.1\|4220258_4220408_-	hypothetical protein	NA	NA	NA	NA
WP_004141720.1\|4220407_4220728_-	hypothetical protein	A0A0M4RU01	Salmonella_phage	3.8e-36	68.9
WP_012542631.1\|4220808_4221000_-	regulatory protein	A0A2R2Z333	Escherichia_phage	3.1e-09	55.4
WP_041165401.1\|4221104_4221815_+	helix-turn-helix domain-containing protein	K7P7K3	Enterobacteria_phage	1.1e-91	71.0
WP_012542633.1\|4221998_4222403_+	hypothetical protein	NA	NA	NA	NA
WP_012542634.1\|4222507_4222684_-	hypothetical protein	NA	NA	NA	NA
WP_019704100.1\|4223108_4223303_+	hypothetical protein	NA	NA	NA	NA
WP_012542636.1\|4223391_4224351_+	hypothetical protein	M9P0E1	Enterobacteria_phage	5.3e-65	90.3
WP_004135670.1\|4224358_4224556_+	hypothetical protein	NA	NA	NA	NA
WP_012542638.1\|4224552_4224711_+	hypothetical protein	B8K1E0	Salmonella_phage	5.8e-06	55.6
WP_012542639.1\|4224707_4225361_+	ERF family protein	A0A1W6JP21	Morganella_phage	4.0e-64	62.3
WP_012542640.1\|4225344_4225635_+	hypothetical protein	NA	NA	NA	NA
WP_012542641.1\|4225631_4225937_+	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_012542642.1\|4225933_4226461_+	hypothetical protein	NA	NA	NA	NA
WP_012542643.1\|4226436_4227099_+	DNA methyltransferase	G8C7S6	Escherichia_phage	8.8e-112	87.5
WP_012542644.1\|4227095_4228268_+	DNA cytosine methyltransferase	Q858D4	Salmonella_phage	9.7e-146	65.6
WP_012542645.1\|4228264_4228483_+	hypothetical protein	NA	NA	NA	NA
WP_012542646.1\|4228484_4228703_+	TraR/DksA family transcriptional regulator	V5USD3	Shigella_phage	1.4e-10	50.0
WP_012542647.1\|4228702_4228942_+	DUF4222 domain-containing protein	Q6H9Z8	Enterobacteria_phage	2.4e-11	47.4
WP_004151317.1\|4228954_4229290_+	excisionase family DNA-binding protein	NA	NA	NA	NA
WP_004143017.1\|4230761_4231628_+	bifunctional methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase FolD	A0A249XZQ2	Enterococcus_phage	1.3e-30	34.8
WP_004143016.1\|4231629_4231842_+	ribosome-associated protein YbcJ	NA	NA	NA	NA
WP_004143010.1\|4231887_4233273_-\|tRNA	cysteine--tRNA ligase	M1PG92	Moumouvirus	3.5e-46	35.4

DBSCAN-SWA_12

4405737 : 4463758

Planktothrix_phage(22.22%)

transposase,protease,integrase

attL 4431233:4431251|attR 4470921:4470939

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_071822057.1\|4405737_4406229_+\|transposase	transposase	NA	NA	NA	NA
WP_012542727.1\|4406409_4408128_+	lysophospholipid acyltransferase family protein	NA	NA	NA	NA
WP_004144604.1\|4408302_4409154_-	taurine dioxygenase	NA	NA	NA	NA
WP_008805332.1\|4409150_4409978_-	taurine ABC transporter permease TauC	NA	NA	NA	NA
WP_004893960.1\|4409974_4410742_-	taurine ABC transporter ATP-binding subunit	G9BWD6	Planktothrix_phage	4.3e-25	38.6
WP_008805331.1\|4410753_4411716_-	taurine ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_008805330.1\|4411940_4412873_-	homocysteine S-methyltransferase	NA	NA	NA	NA
WP_008805329.1\|4412859_4414269_-	S-methylmethionine permease	NA	NA	NA	NA
WP_012542728.1\|4414351_4414468_-	hypothetical protein	NA	NA	NA	NA
WP_012542729.1\|4414542_4415922_+	ethanolamine permease	NA	NA	NA	NA
WP_012542730.1\|4415931_4417320_+	ethanolamine ammonia-lyase subunit EutB	NA	NA	NA	NA
WP_012542731.1\|4417316_4418096_+	ethanolamine ammonia-lyase subunit EutC	NA	NA	NA	NA
WP_042929599.1\|4418533_4418677_-	hypothetical protein	NA	NA	NA	NA
WP_004147267.1\|4418669_4419776_+	ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_002890128.1\|4419795_4420695_+	branched-chain amino acid ABC transporter permease	NA	NA	NA	NA
WP_008805324.1\|4420694_4421744_+	branched-chain amino acid ABC transporter permease	NA	NA	NA	NA
WP_008805323.1\|4421730_4422513_+	ABC transporter ATP-binding protein	W6JKT0	Anomala_cuprea_entomopoxvirus	8.8e-10	24.8
WP_004204908.1\|4422505_4423201_+	ABC transporter ATP-binding protein	W6JKT0	Anomala_cuprea_entomopoxvirus	1.1e-06	23.9
WP_012542732.1\|4423317_4423494_-	hypothetical protein	NA	NA	NA	NA
WP_002890106.1\|4423932_4424742_+	ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_008805322.1\|4424743_4425562_+	amino acid ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	5.3e-34	41.9
WP_012542734.1\|4425558_4426311_+	amino acid ABC transporter permease	NA	NA	NA	NA
WP_008805320.1\|4426300_4426990_+	amino acid ABC transporter permease	NA	NA	NA	NA
WP_012542735.1\|4426993_4427704_-	fimbria/pilus periplasmic chaperone	NA	NA	NA	NA
WP_008805318.1\|4427672_4429316_-	hypothetical protein	NA	NA	NA	NA
WP_012542736.1\|4429305_4431831_-	fimbrial usher EcpC	NA	NA	NA	NA
4431233:4431251	attL	NA	NA	NA	NA
WP_008805316.1\|4431856_4432525_-	fimbrial chaperone EcpB	NA	NA	NA	NA
WP_012542737.1\|4432583_4433171_-	common pilus major fimbrillin subunit EcpA	NA	NA	NA	NA
WP_008805314.1\|4433245_4433788_-	LuxR family transcriptional regulator	NA	NA	NA	NA
WP_012542738.1\|4434631_4435474_+	phosphonate ABC transporter ATP-binding protein	A0A2R8FG22	Brazilian_cedratvirus	5.4e-13	25.8
WP_032691132.1\|4435496_4436435_+	phosphonate ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_008805311.1\|4436502_4437375_+	phosphonate ABC transporter, permease protein PhnE	NA	NA	NA	NA
WP_012542739.1\|4437371_4438256_+	phosphonate ABC transporter, permease protein PhnE	NA	NA	NA	NA
WP_012542740.1\|4438628_4439294_-	HAD-IB family hydrolase	NA	NA	NA	NA
WP_008805308.1\|4439389_4440259_-	DMT family transporter	NA	NA	NA	NA
WP_004222859.1\|4440670_4441237_+	C40 family peptidase	NA	NA	NA	NA
WP_008805307.1\|4441281_4442334_-	phosphoporin PhoE	Q1MVN1	Enterobacteria_phage	1.4e-111	57.9
WP_008805306.1\|4442623_4443727_+	glutamate 5-kinase	A0A1X9I5D0	Streptococcus_phage	8.2e-62	40.5
WP_008805305.1\|4443737_4444991_+	glutamate-5-semialdehyde dehydrogenase	A0A1X9I5D4	Streptococcus_phage	1.2e-88	44.9
WP_012542743.1\|4445639_4445843_-	hypothetical protein	NA	NA	NA	NA
WP_008804422.1\|4445839_4446016_-	hypothetical protein	NA	NA	NA	NA
WP_041165403.1\|4446016_4446352_-	hypothetical protein	NA	NA	NA	NA
WP_012542745.1\|4446344_4446866_-	hypothetical protein	NA	NA	NA	NA
WP_012542749.1\|4448132_4448450_+	hypothetical protein	NA	NA	NA	NA
WP_041165404.1\|4448496_4448859_-\|protease	protease inhibitor I42 family protein	NA	NA	NA	NA
WP_012542751.1\|4449197_4449821_-	recombinase family protein	NA	NA	NA	NA
WP_012542752.1\|4450072_4450639_+	hypothetical protein	NA	NA	NA	NA
WP_012542753.1\|4450875_4452084_-\|integrase	tyrosine-type recombinase/integrase	NA	NA	NA	NA
WP_001412614.1\|4452424_4453639_+\|integrase	tyrosine-type recombinase/integrase	Q7M297	Enterobacteria_phage	3.8e-129	54.4
WP_001412615.1\|4453787_4454645_+	hypothetical protein	NA	NA	NA	NA
WP_001075424.1\|4454735_4454942_+	AlpA family transcriptional regulator	NA	NA	NA	NA
WP_012542754.1\|4455267_4455777_+	hypothetical protein	NA	NA	NA	NA
WP_012542755.1\|4455978_4456392_+	hypothetical protein	NA	NA	NA	NA
WP_012542756.1\|4456388_4457666_+	relaxase/mobilization nuclease domain-containing protein	NA	NA	NA	NA
WP_012542757.1\|4457971_4458637_+	hypothetical protein	NA	NA	NA	NA
WP_039021687.1\|4458694_4459108_-	hypothetical protein	NA	NA	NA	NA
WP_012542759.1\|4459204_4459609_-	hypothetical protein	NA	NA	NA	NA
WP_012542760.1\|4459609_4461241_-	DNA-binding protein	NA	NA	NA	NA
WP_041165405.1\|4461237_4462551_-\|integrase	site-specific integrase	NA	NA	NA	NA
WP_012542762.1\|4462552_4463758_-\|integrase	site-specific integrase	NA	NA	NA	NA
4470921:4470939	attR	NA	NA	NA	NA

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. NC_011281

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection

2. NC_011282

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection

3. NC_011283

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection