CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Target MGE spacer number	Prophage number
NC_010553	Burkholderia ambifaria MC40-6 plasmid pBMC401, complete sequence	0 crisprs	RT,PD-DExK	0	3
NC_010552	Burkholderia ambifaria MC40-6 chromosome 2, complete sequence	0 crisprs	RT,cas3,csa3,c2c9_V-U4,Cas14u_CAS-V,DinG,DEDDh	0	0
NC_010557	Burkholderia ambifaria MC40-6 chromosome 3, complete sequence	1 crisprs	cas14j,c2c9_V-U4,csa3,Cas14u_CAS-V	1	0
NC_010551	Burkholderia ambifaria MC40-6 chromosome 1, complete sequence	6 crisprs	cas3,DEDDh,csa3,c2c9_V-U4,Cas14u_CAS-V,DinG	1	3

Results visualization

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CRISPR-Cas detection and classification

Crispr_ID: NC_010557_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_010557_1

176537-176613

Orphan

Consensus_repeat	Method
GACACACGTCCGGCATCGGCCGC	CRISPRCasFinder

1 spacers

The CRISPR arrays of NC_010557_1

>merge|NC_010557|1|176537-176613|CRISPRCasFinder
GACACACGTCCGGCATCGGCCGCGGCGGTCACATCGGCGGTCGCGGAAACCCAAGACATACGTCCGGCATCGGCCGC

>NC_010557|1|1|176537-176613|CRISPRCasFinder
GACACACGTCCGGCATCGGCCGC	GGCGGTCACATCGGCGGTCGCGGAAACCCAA
GACATACGTCCGGCATCGGCCGC

Protein	Signature genes	Signature genes Name	Protein_function
NC_010557.1\|WP_012372048.1\|179630_179936_-\|hypothetical-protein	unknown	unknown	unknown
NC_010557.1\|WP_012372047.1\|179251_179611_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|312947
NC_010557.1\|WP_012372042.1\|172201_173635_+\|helix-turn-helix-transcriptional-regulator	unknown	unknown	gnl\|CDD\|197666
NC_010557.1\|WP_050772572.1\|185388_185607_-\|hypothetical-protein	unknown	unknown	unknown
NC_010557.1\|WP_012372038.1\|166586_167177_-\|type-IV-pilus-biogenesis-protein-PilP	unknown	unknown	gnl\|CDD\|274394
NC_010557.1\|WP_012372039.1\|167166_168483_-\|type-4b-pilus-protein-PilO2	unknown	unknown	gnl\|CDD\|369114
NC_010557.1\|WP_012372037.1\|164797_166582_-\|secretion-system-protein-E	unknown	unknown	gnl\|CDD\|225363
NC_010557.1\|WP_012372036.1\|163062_163617_-\|pilus-biosynthesis-protein	unknown	unknown	gnl\|CDD\|285957
NC_010557.1\|WP_012372040.1\|168508_170242_-\|PilN-family-type-IVB-pilus-formation-outer-membrane-protein	unknown	unknown	gnl\|CDD\|274177
NC_010557.1\|WP_012372046.1\|178029_178845_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|380090
NC_010557.1\|WP_012372050.1\|182098_182953_+\|formyl-transferase	unknown	unknown	gnl\|CDD\|223301
NC_010557.1\|WP_012372052.1\|185549_186521_-\|oxidoreductase	unknown	unknown	gnl\|CDD\|99782
NC_010557.1\|WP_011660767.1\|163731_164808_-\|type-II-secretion-system-protein-F	unknown	unknown	gnl\|CDD\|224376
NC_010557.1\|WP_006750733.1\|184402_184891_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|312947
NC_010557.1\|WP_012372053.1\|186543_187941_-\|sodium:sulfate-symporter	unknown	unknown	gnl\|CDD\|273267
NC_010557.1\|WP_012372051.1\|183119_184250_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|240291
NC_010557.1\|WP_012372043.1\|173809_174277_+\|lytic-transglycosylase-domain-containing-protein	unknown	unknown	gnl\|CDD\|381603
NC_010557.1\|WP_012372044.1\|174497_175031_-\|hypothetical-protein	unknown	unknown	unknown
NC_010557.1\|WP_012372049.1\|180169_181930_+\|hypothetical-protein	unknown	unknown	unknown
NC_010557.1\|WP_012372041.1\|170241_171402_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|378468

Protein	Function_ID	Function_description	E-value
NC_010557.1\|WP_012372042.1\|172201_173635_+\|helix-turn-helix-transcriptional-regulator	gnl\|CDD\|197666	smart00342, HTH_ARAC, helix_turn_helix, arabinose operon control protein.	7.66388e-16
NC_010557.1\|WP_012372038.1\|166586_167177_-\|type-IV-pilus-biogenesis-protein-PilP	gnl\|CDD\|274394	TIGR03021, pilP_fam, type IV pilus biogenesis protein PilP. Members of this protein family are found in type IV pilus biogenesis loci and include proteins designated PilP. [Cell envelope, Surface structures].	3.34116e-10
NC_010557.1\|WP_012372039.1\|167166_168483_-\|type-4b-pilus-protein-PilO2	gnl\|CDD\|369114	pfam06864, PAP_PilO, Pilin accessory protein (PilO). This family consists of several enterobacterial PilO proteins. The function of PilO is unknown although it has been suggested that it is a cytoplasmic protein in the absence of other Pil proteins, but PilO protein is translocated to the outer membrane in the presence of other Pil proteins. Alternatively, PilO protein may form a complex with other Pil protein(s). PilO has been predicted to function as a component of the pilin transport apparatus and thin-pilus basal body. This family does not seem to be related to pfam04350.	2.0215e-46
NC_010557.1\|WP_012372037.1\|164797_166582_-\|secretion-system-protein-E	gnl\|CDD\|225363	COG2804, PulE, Type II secretory pathway, ATPase PulE/Tfp pilus assembly pathway, ATPase PilB [Cell motility and secretion / Intracellular trafficking and secretion].	2.01617e-75
NC_010557.1\|WP_012372036.1\|163062_163617_-\|pilus-biosynthesis-protein	gnl\|CDD\|285957	pfam08805, PilS, PilS N terminal. Type IV pili are bacterial virulence-associated adhesins that promote bacterial attachment to host cells. In Salmonella typhi, the structural pilin protein PilS interacts with the cystic fibrosis transmembrane conductance regulator. Mutagenesis studies suggest that residues on an alpha-beta loop and the C terminal disulphide-bonded region of PilS might be involved in binding specificity of the pilus.	1.55004e-16
NC_010557.1\|WP_012372040.1\|168508_170242_-\|PilN-family-type-IVB-pilus-formation-outer-membrane-protein	gnl\|CDD\|274177	TIGR02520, putative_Type_IV_pilus_protein, type IVB pilus formation outer membrane protein, R64 PilN family. Several related protein families encode outer membrane pore proteins for type II secretion, type III secretion, and type IV pilus formation. This protein family appears to encode a secretin for pilus formation, although it is quite different from PilQ. Members include the PilN lipoprotein of the plasmid R64 thin pilus, a type IV pilus. Scoring between the trusted and noise cutoffs are examples of bundle-forming pilus B (bfpB). [Cell envelope, Surface structures, Protein fate, Protein and peptide secretion and trafficking].	1.10634e-143
NC_010557.1\|WP_012372046.1\|178029_178845_+\|hypothetical-protein	gnl\|CDD\|380090	pfam18013, Phage_lysozyme2, Phage tail lysozyme. This domain has a lysozyme like fold. It is found in the tail protein of various phages probably giving them the ability to degrade the host cell wall peptidoglycan layer.	2.51574e-28
NC_010557.1\|WP_012372050.1\|182098_182953_+\|formyl-transferase	gnl\|CDD\|223301	COG0223, Fmt, Methionyl-tRNA formyltransferase [Translation, ribosomal structure and biogenesis].	9.2246e-31
NC_010557.1\|WP_012372052.1\|185549_186521_-\|oxidoreductase	gnl\|CDD\|99782	cd06185, PDR_like, Phthalate dioxygenase reductase (PDR) is an FMN-dependent reductase that mediates electron transfer from NADH to FMN to an iron sulfur cluster. PDR has an an N-terminal ferrredoxin reductase (FNR)-like NAD(H) binding domain and a C-terminal iron-sulfur [2Fe-2S] cluster domain. Although structurally homologous to FNR, PDR binds FMN rather than FAD in it's FNR-like domain. Electron transfer between pyrimidines and iron-sulfur clusters (Rieske center [2Fe-2S]) or heme groups is mediated by flavins in respiration, photosynthesis, and oxygenase systems. Type I dioxygenase systems, including the hydroxylate phthalate system, have 2 components, a monomeric reductase consisting of a flavin and a 2Fe-2S center and a multimeric oxygenase. In contrast to other Rieske dioxygenases the ferredoxin like domain is C-, not N-terminal.	1.31154e-82
NC_010557.1\|WP_011660767.1\|163731_164808_-\|type-II-secretion-system-protein-F	gnl\|CDD\|224376	COG1459, PulF, Type II secretory pathway, component PulF [Cell motility and secretion / Intracellular trafficking and secretion].	3.98255e-21
NC_010557.1\|WP_006750733.1\|184402_184891_-\|hypothetical-protein	gnl\|CDD\|312947	pfam09613, HrpB1_HrpK, Bacterial type III secretion protein (HrpB1_HrpK). This family of proteins is encoded by genes found within type III secretion operons in a limited range of species including Xanthomonas, Ralstonia and Burkholderia.	3.54946e-21
NC_010557.1\|WP_012372053.1\|186543_187941_-\|sodium:sulfate-symporter	gnl\|CDD\|273267	TIGR00785, Uncharacterized_transporter_HI_0020, anion transporter. The Divalent Anion:Na+ Symporter (DASS) Family (TC 2.A.47) Functionally characterized proteins of the DASS family transport (1) organic di- and tricarboxylates of the Krebs Cycle as well as dicarboxylate amino acid, (2) inorganic sulfate and (3) phosphate. The animal NaDC-1 cotransport 3 Na+ with each dicarboxylate. Protonated tricarboxylates are also cotransported with 3Na+. [Transport and binding proteins, Anions, Transport and binding proteins, Cations and iron carrying compounds].	2.3487e-15
NC_010557.1\|WP_012372051.1\|183119_184250_-\|hypothetical-protein	gnl\|CDD\|240291	PTZ00146, PTZ00146, fibrillarin; Provisional.	0.00360752
NC_010557.1\|WP_012372043.1\|173809_174277_+\|lytic-transglycosylase-domain-containing-protein	gnl\|CDD\|381603	cd13400, LT_IagB-like, Escherichia coli invasion protein IagB and similar proteins. Lytic transglycosylase-like protein, similar to Escherichia coli invasion protein IagB. IagB is encoded within a pathogenicity island in Salmonella enterica and has been shown to degrade polymeric peptidoglycan. IagB-like invasion proteins are implicated in the invasion of eukaryotic host cells by bacteria. Lytic transglycosylase (LT) catalyzes the cleavage of the beta-1,4-glycosidic bond between N-acetylmuramic acid (MurNAc) and N-acetyl-D-glucosamine (GlcNAc), as do "goose-type" lysozymes. However, in addition to this, they also make a new glycosidic bond with the C6 hydroxyl group of the same muramic acid residue. Members of this family resemble the soluble and insoluble membrane-bound LTs in bacteria and the LTs in bacteriophage lambda.	1.23866e-54
NC_010557.1\|WP_012372047.1\|179251_179611_-\|hypothetical-protein	gnl\|CDD\|312947	pfam09613, HrpB1_HrpK, Bacterial type III secretion protein (HrpB1_HrpK). This family of proteins is encoded by genes found within type III secretion operons in a limited range of species including Xanthomonas, Ralstonia and Burkholderia.	1.13226e-09
NC_010557.1\|WP_012372041.1\|170241_171402_-\|hypothetical-protein	gnl\|CDD\|378468	pfam10671, TcpQ, Toxin co-regulated pilus biosynthesis protein Q. The toxin-coregulated pilus (TCP) of Vibrio cholerae and the soluble TcpF protein that is secreted via the TCP biogenesis apparatus are essential for intestinal colonisation in the disease of cholera. TcpQ is part of an outer membrane complex of the TCP biogenesis apparatus, comprised of TcpC and TcpQ, and the TcpQ is required for proper localization of TcpC to the outer membrane. The domain is found in other Proteobacterial species apart from Vibrio.	7.01485e-22

>NC_010557.1|WP_012372044.1|174497_175031_-|hypothetical-protein
MNNLGIRPGLVQSRVAEFEKGTKNGATDGAQKQSPARNTGQLGGLSSFKGTDGAPPPPPAPPRNFASLPGRAGNVGAQVLSSALHAGSHFLPPGVASTAMHAAGDIVRPSALGAGDPVTQMAAMQNDFMKQQSEMTRLNNANTLAAAVNQQSQELTSALASVGNKGASNISNAAKGQ
>NC_010557.1|WP_012372043.1|173809_174277_+|lytic-transglycosylase-domain-containing-protein
MMRLFTPKPALALALAVLSARPAEVRAQTPDCFAAAAAYQHVSPVVLRAIAWQESHGNANALHRNRNGSTDYGMMQINSIHLPLLSRYGVSADDLMNPCLSVYVAAWHLHKMMVKYGNNWAAIGAYHSETPAERDRYARSVQSIVERMKLADDGQ
>NC_010557.1|WP_012372042.1|172201_173635_+|helix-turn-helix-transcriptional-regulator
MFSTIYFAAASALAFDDTPADVASKMLQGQFLDAVRHAARHADTDTAQAQPGYAQLQVCADLELMLGRHEEAEETYRRAQKAIRAQRDGLRIASCRNTGWQAFFRNQFNVALSCFKRVGEEKAATPHQRLDSLVGATLVSFHLGLIQAACHRLGELAALAATHGDRRWSYLVEALRRDLFAQHELHGAERLADHIYWRSAIGEFEPSEAPVPGSQPAGTVLPLLAERLSHLNRLVSLADGRTSAGETLKQYVSWSRQAGLNDYHRSLCLEITLAAIAGHATPLAEAMLDASGAANSQGSQHARWYLDYLYCRAKIMQQQMRTQEFAQFYGRYALASIQHVRADMSMPAAAADHMQASRTAQRSDDVSARLPAKYRRAYRYLMDNLDQKDLSVREVASHVGVTERAMQAAFKNHLGLSPSELIRRQRMERIRDDLLDDGAPATRVLDVANKWGVRHRSTLINGYRRVFQEAPSETMGR
>NC_010557.1|WP_012372041.1|170241_171402_-|hypothetical-protein
MPPAIRALLCGVWFACTVAHASDQQVIVDGGQRLGGVVRTGGHDVPLLRALEQIMPTSYSINVPNAGAWADASVSWRAGSSVVHALGEVLSVDPALQARVDTDMHLLTVTAHARRANVDAPQPSSPAAGAASRMNSAATNASSTVPTGAATMAPAAGPAIAAAQPLVQARVSTWIPATPASARIPAATLAVPPVPASAPAPAPAPVMSSAPAAGPAMPASAPAPAPALAMPPAPAPAPAMPAPVPALVSAPPRAQVPAPAKRDAIEPPLLAATQPASGPASPAPSSAPAATPAFVPAAAPERTEWQMRLSDGSVRNALARWASEAGWQFIWDVPTDFQVDATATIHGTLAEALRQVTNALAGSQVPIQVVLYQRNHVMRVVPKGAS
>NC_010557.1|WP_012372040.1|168508_170242_-|PilN-family-type-IVB-pilus-formation-outer-membrane-protein
MSVLRRPFVVLAACLSLLAGCTGLLDKIERNSQSDTARAGQLLGKLSNGDNRAVPGSDDVIVKDELWLSGKTIKIATKSTLPKLFDEPASFDGTVDSLRMFADRISRLAHLPAKVAPGTSEAAARATQTAVDTGGAGAYPGVPPLPAGLLQGPAPSTSAATVAARVPSVSSPVRIAYSRGPLRGLLDTASARFGVYWKYEDGAIVFFYTATRVYQVVAIPGDSKLDTNVVSGASNSGGASSNSAGAAGGSGAGGAGIGGGGGGTSGSPSVSSDNTANITMNAQLSVYNGLQTAIKAMLSPAGSVITSPATGSIAVTDTPDVLERVGEFMDQQNRVLARQVLINVTVLSVTLSAADSYGINWHAVYQALGTQFGITTAFTSMIQNPSELSASVITPSSRASSTTAVIDALSTQGTVHRKTSASITTLNDQPVPVQVAEQQGYLAQISTTNTVNIGSQTSLTPGTITTGFNLTVLPHILDDGTIMMQFYSNISSLVNLAPFGPANQQIQLPTVDTRNFLQRIAVKSGQTLVISGYEGITDQDNRQGVGHPSNYAMGGFNASGTREVIVILLSPIAINGA
>NC_010557.1|WP_012372039.1|167166_168483_-|type-4b-pilus-protein-PilO2
MATQVIQIGRQRFICGLFWQSLSRRHALRAEAVELAARLNFDAMVLRIDRTFAGAGFASTREGAQLGLPSLGALVSKTIAAEGAFYDGRQQPAPNWLGAFHLPDGRWAYFAVRDGAFLPNGDRIGSSEEVFERLHSDYSLGGWNVVIGDPQLEVQGFHNFYARRIEDMIPRRGGKPHLPRWLNLSRVSRRAPRREVLLVAVAIVVAAAVVAGIVAYRRHRMELERQQAFERMRAELALHPPKPAAPPEAAHPWASEPRPDAFVRACLDHFTHIAPGGWELDDYVCRASNVSYSWSRDGSNVAMLMAAEPRATIDGNGEHASYVEPLALPVGGDEVIDGVRGVRLRMLSAFQLLGIGLTFTLQPASAPQRSLASQTLDRLHPDGGPPPAPSWQTWRMSAQLGGVRPDSLIRYLDEPGVRVETLSYKSGQWTLDGVLYEK
>NC_010557.1|WP_012372038.1|166586_167177_-|type-IV-pilus-biogenesis-protein-PilP
MRNDDALTVLVLACCWAWPLAASGAASAAAATAAAPAEAAPRMNVVPTPAAVQAANELMRLQEETMILKAQLKKLDAQAQVAERQEALHRMGSTVSSYSDVSLVATQGLGKKLSATVATSDGAEFDVGPGDALPNGMRVAAIRPGAIVLASQDGRRTTLTVSASARQQPARSNVASTGSPGVPPVPTLPALPMPAR
>NC_010557.1|WP_012372037.1|164797_166582_-|secretion-system-protein-E
MSSSPTPPGKTPTSVTPLILSRAVKPVETDPSVTQGQPAAPAGPALAPVARPREPVLSAVAAAAAASVQPAQTASQSQPPGQVLPLAAVARPLSDSGEFAASDEERKFLCLLDDGTLLVAEGHEMNPFVLSYCARLERLNCHYTTRLVTLDAIRRSYQGPRRDGSAERIDHTRMQVLAKNLIARACDERASDIHIRVNRFSTEILFRIHNELVRISEQTREYGERLLATLYAAMSSVSDNTYKPNERQDAAIGDRDKLPDRLFGVRIATAPTSVGSVMVLRLLYNDAGEATALTELGFTVAQANAFELLAQQPHGMNIISGPTGSGKSTTLQRVLTKQLREMAGSIHVITVEDPVEYPIEGAVQTPVVNAPTEEARSLAFAAAIANAMRLDPDTIMIGEVRDRASAQSALRAAMTGHQVWTTVHANGALAIVDRLVDLGLPIAMVTDESLVTGLISQRLAKLLCPHCSRPLAEAMAQLDMGLVARVKRAVGARFDAVRVAGPGCPNCKNGTVGRTVVAEVVRTDATFCELLRAGRKPDAQAYWLSELAGQTVAQHALEKVAAGLIDPRMAERVVGPFMPGSGGRPQPLGSGYGT
>NC_010557.1|WP_011660767.1|163731_164808_-|type-II-secretion-system-protein-F
MALELNRRWARLQFTTQARLRLYRKIAKMLANGLPLLKILEELELRASHEGRKPNEPLALTLADWRSVVQNGGMLAEAMAWWVPHTEQMIVMAGEQSGRLEAALLNVCTVVQYSRRIRTAIVGGLTYPCVIVAMTIGYVYLFGKLVIPRFASIVSPERWHGVAKSLYELSRFVQGGMIYCLVVLAILVAALFYSMPRWSGNVRVWLDRYPPYSIYRLITGCGFLVAFSSLQAAGFTVERSLARLATDAKPWLRQRIDDMLFGVKSGLNVGEAMKNAGYRFPSEEIVDDLCVYAEYKGFAEALHAIASEWMTDGVETIEAQMRVVNGAAIVVLALVLSWLISGFFGIQQEIAALARSLH
>NC_010557.1|WP_012372036.1|163062_163617_-|pilus-biosynthesis-protein
MNVKTVASIRARVGSRRSRRMQRGATLLEAIAYLGIAAIVVIGAIALLRGAFGSASSNQTAEQVTAIQTGVKKLYMGQTNGYTGLTTTVAIGAGIIPTTLVIDTAANTVTDAWGGAVTITGTGTGTFTIEFDTVPTDVCINAASAGGTWTAVSIGGAAQTVPVTPAAAQAACAGGAKNIIWTSA
>NC_010557.1|WP_012372046.1|178029_178845_+|hypothetical-protein
MSTTAVQGYNAGYLNSIDDVGGIGGTNESQLAQLLELLIEEIKQILDPSSQNSGDAGGVGGIGGGTPSYSAPPAFAGGGGAAPAGVSGGGGGHGGGGASPGIGGGGSGGGGSHGNTLPTVSGGDAAHAIAQDLKSRYGLTDAQVAGVLGNLQQESGLQGNVNQGGAKGAPSGNFADDNANGWGLAQWGGTRKQGEINYAKEHGLDPGSLEANIGFMNQELDTTYSKTITDIKQTTTAEQAALVWDKDYEQATDPQMENRNKYAEQFLAQGF
>NC_010557.1|WP_012372047.1|179251_179611_-|hypothetical-protein
MMELLTELPADAPAIAQAIIEHIEANELDEAEALLARMHDVYPETREVHVFAVTIALVRGRPHEAWQVVNGLPDDRAPELKAICLKVLDDPSWHGYATAHEDSADPYVRLAMRRLLERH
>NC_010557.1|WP_012372048.1|179630_179936_-|hypothetical-protein
MSFIGNIVKSVVGDVTKAAGGVLHGVGNALHGAATFGKGLLSGNPKEALAGAGAIATGGLEALEGGTALAENLTPEGAATALALAGGKEAVRTLTSGTGAA
>NC_010557.1|WP_012372049.1|180169_181930_+|hypothetical-protein
MTGPHSAVHLVSRSENIMAPPPKIEFHSHAIESASLTRTTSDPGPSTGAKPAPVPTRRASAGALIEELGSLGKRPCAEGLPAAPAAPRPAAAIAPQKPGVDDIGAFVPGAGGKGRRFADFAHAMGVNRKGMTLTAFAAKRPAKDGLNGVSTATHGQFGYDAAPATDLVNALASGSNAAAAHSIHGRYENKVKAMLAADVERFEHPEKRPPGAPMPNQVENLLLTKNSNGGWQYDKGKLSRIARDDAHPLTQHARDVLTAMSIAENKGKQRNGALYQSVTSAIGLTASGLLIGGSHGALAPLAASGHLTNAVKEALDLKKPFVEGRQNLRNAKAATIQRYVDTVLAPHDYTGQTQDERLRAALQTSRAKIDDLRAMEARPADEGLPADLRSPQAQAGIYASLYDDARRYANSTTSFGKRLISGMHAEDKAKVHKDAERDIVVKHILSMVTKSIGRLDPASLAALAGADMAVDASGSQRARQALAIVGNHPRASRNQDLIAAHTLLTDSGIPKGEAALLLSQLARARREKPQEAPAPSDTSAASRSAAPLTESERLKQIANIIGQPGLTATAAKTAEDAIKKNLGLRS
>NC_010557.1|WP_012372050.1|182098_182953_+|formyl-transferase
MRFAFAGFDRWRVVFDAFVAAGWEPVALYSIPVDNRLDFNSELVERAEKLRIPVQLSRIDEDDLSWLAERQCDALIVAGYNRKIPAWQPYLRHAANFHPSPLPDGRGPYPAMRAILEGRREWGVSCHRIDADFDTGEIVDSECFPLDADEWHETLQLKLQMAAHRLATRVARDFDRLWNERRPQGAGSYWPRVADAERTIDFAQPVAEVMRVVRACGNVESIAPLFGTTVHVRRATAWHEAHTYEPGQIVHQYRRWVVVAAQDGFVALLEWSPLNASLRQQMEG
>NC_010557.1|WP_012372051.1|183119_184250_-|hypothetical-protein
MNLNVPSMNTYPTDPASYLQRLTNGASTGSTQDVLKDLIGLISQLLKQMQAGQNGQAGGMPGGAGGAGGMPGGTPGGMAGGGAGAMPGGVGATPGGMGGAGAMPGGTGGMTVQNAAGVLASYMGQHGLSASDPNTMYKLSTNADGGTPPTVQQAAQTMLANPGAYQQIETHDVAGTDGKSAVSNFQWAAQGGLGAAGNATGGAGGVAGQSGTTGGLPGTGGFPANTSTLPTTGGLPTTGATAGFTPGTGDLLKDGKPLQMADEGKALANFNAQDGADFQAMESALSHGDGNAAAKTLANAVKSGKLSQSDAAAIGAQLQQTANAHGGGKISHDASKALSDALGGANVLTPGKTRAAVAFENITGIHTGTIAGVSTK
>NC_010557.1|WP_006750733.1|184402_184891_-|hypothetical-protein
MTYTGCRDEIAGGLTKVLWTASQLDDEADFEDLLEAIRVLRPKWPGAGTVAAWRYVRRQAWGDARRVLEDDDTEAKRSGLHAALMAVCLFGLEDPLWHSYALSAAEQRESIEGATIGARLLERAAKLDASVQAPASTDAPASTHGVPADNSGFSASMTWVRA
>NC_010557.1|WP_050772572.1|185388_185607_-|hypothetical-protein
MHDAVRVAMPWRTAGAGSVSRHGGLCALANWVRAAKAGKLKDVGRHRKPLTEMEVERAQVKRELAEVKMERD
>NC_010557.1|WP_012372052.1|185549_186521_-|oxidoreductase
MIENDLLAARVIARERVACDVISLRLVSDAPGLALPAFEAGAHIDLHLRDGLTRKYSLCNDPVERGVYEIAIKREPASSGGSAHVHDAIRVGDVLRIGAPLNYFPLAPDDSPAVLLAAGIGVTPLLAMAHSLVRAGRSLAFHYFVRSADAAAYGATLASRLADVATMHTGLTPDATRDAITTIVGAMDSRSHLYFCGPAPFMAAVDAIARPALGDARLHHEYFSAPAAEPADGEADAFRIELARSQRALLVPSGQSITDVLYEHGIAVATSCEAGVCGACRTTVLEGTPDHRDAFLSAAEKARNDCMMPCVSRCRGERLVLDL
>NC_010557.1|WP_012372053.1|186543_187941_-|sodium:sulfate-symporter
MSGSALGGPGRGAGMLTGGRVTAVLLAAGLASVAALGARGTLSAGDARIVAIVFTCIVLWATGAVASLWVSLLFFFLAATCTAVPTAEIFSGFGSSAFWLVFSGAAIGFALKESGLSERIGIALARRIGGSYLKALLAFAILSFLLSLVMPSTFGRIAILVPIAIGYCDVVKLGAHANGRRGILLLVIVGSYELAAAVLPANLPNVIMAGILEQSHGMHLRFSEYLLLFFPAGVIVRGAVLVLASWWLFADTVGEVEIPAARVALGRREWHAIVLLAITLAFWFTDAVHRIAPGWVGLGFALVYFGTSPPARLERFTATLKMDLLWFIAAIIGLTALVNHLDMRVPDTLALDALRDSPMLVYFALTALSIVVCFAVTSNAEPALYVPIVSRLLAQGLHLKAGLLAQVMGYATTVLPYQSPPIVFGNALAQLDRGAVLRYCIATALLGVVFVIPVNALWWRLIGLM

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Click the colored protein region to show detailed information

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NC_010557_1	1.1\|176560\|31\|NC_010557\|CRISPRCasFinder	176560-176590	31	NZ_CP034087	Methylocystis rosea strain GW6 plasmid pGW6_1, complete sequence	48052-48082	7	0.774
NC_010557_1	1.1\|176560\|31\|NC_010557\|CRISPRCasFinder	176560-176590	31	NZ_CP007130	Gemmatirosa kalamazoonesis strain KBS708 plasmid 2, complete sequence	856894-856924	8	0.742
NC_010557_1	1.1\|176560\|31\|NC_010557\|CRISPRCasFinder	176560-176590	31	NZ_CP043499	Rhizobium grahamii strain BG7 plasmid unnamed, complete sequence	512907-512937	9	0.71
NC_010557_1	1.1\|176560\|31\|NC_010557\|CRISPRCasFinder	176560-176590	31	CP016641	Mycobacterium sp. djl-10 plasmid djl-10_1, complete sequence	2693-2723	9	0.71

1. spacer 1.1|176560|31|NC_010557|CRISPRCasFinder matches to NZ_CP034087 (Methylocystis rosea strain GW6 plasmid pGW6_1, complete sequence) position: , mismatch: 7, identity: 0.774

ggcggtcacatcggcggtcgcggaaacccaa	CRISPR spacer
ggcggtcacagcggcggtcgcgggcggacag	Protospacer
********** ************. .  **.

2. spacer 1.1|176560|31|NC_010557|CRISPRCasFinder matches to NZ_CP007130 (Gemmatirosa kalamazoonesis strain KBS708 plasmid 2, complete sequence) position: , mismatch: 8, identity: 0.742

ggcggtcacatcggcggtcgcggaaacccaa	CRISPR spacer
ggcggtcgcgtcggcggtcgcggcgacgtcg	Protospacer
*******.*.************* .** . .

3. spacer 1.1|176560|31|NC_010557|CRISPRCasFinder matches to NZ_CP043499 (Rhizobium grahamii strain BG7 plasmid unnamed, complete sequence) position: , mismatch: 9, identity: 0.71

ggcggtcacatcggcggtcgcggaaacccaa	CRISPR spacer
ggcggccacgtcggcggtcgcggagctgtcg	Protospacer
*****.***.**************. . . .

4. spacer 1.1|176560|31|NC_010557|CRISPRCasFinder matches to CP016641 (Mycobacterium sp. djl-10 plasmid djl-10_1, complete sequence) position: , mismatch: 9, identity: 0.71

ggcggtcacatcggcggtcgcggaaacccaa	CRISPR spacer
ggcagtcacagcggcggtcgcggcggcgttg	Protospacer
***.****** ************ ..* . .

Prophage detection

Region	Region Position	Protein_number	Hit_taxonomy	Key_proteins	Att_site	Prophage annotation

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

45190 : 88792

Ralstonia_phage(33.33%)

transposase,integrase

attL 81016:81032|attR 91395:91411

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_012363394.1\|45190_46513_+\|transposase	IS4 family transposase	NA	NA	NA	NA
WP_012367216.1\|46543_47152_-	hypothetical protein	NA	NA	NA	NA
WP_012367217.1\|47165_48380_-	hypothetical protein	NA	NA	NA	NA
WP_012367218.1\|48389_48983_-	hypothetical protein	NA	NA	NA	NA
WP_012367219.1\|48991_50125_-	hypothetical protein	NA	NA	NA	NA
WP_012367220.1\|50121_52389_-	secretion system protein E	NA	NA	NA	NA
WP_012367221.1\|52385_53003_-	hypothetical protein	NA	NA	NA	NA
WP_012367222.1\|52956_54288_-	hypothetical protein	NA	NA	NA	NA
WP_012367223.1\|54292_55903_-	type II secretory pathway protein	NA	NA	NA	NA
WP_012367224.1\|55908_56439_-	hypothetical protein	NA	NA	NA	NA
WP_012367225.1\|56441_56864_-	lytic transglycosylase domain-containing protein	A0A0K2QQJ4	Ralstonia_phage	8.6e-12	39.4
WP_012367226.1\|56860_58147_-	TrbG/VirB9 family P-type conjugative transfer protein	NA	NA	NA	NA
WP_012367227.1\|58143_58953_-	transglycosylase SLT domain-containing protein	NA	NA	NA	NA
WP_012367228.1\|58949_60209_-	TrbI/VirB10 family protein	NA	NA	NA	NA
WP_012367229.1\|60218_61100_-	TrbG/VirB9 family P-type conjugative transfer protein	NA	NA	NA	NA
WP_012367230.1\|61096_61813_-	type IV secretion system protein	NA	NA	NA	NA
WP_012367231.1\|62096_62645_+	hypothetical protein	NA	NA	NA	NA
WP_012367232.1\|62865_63426_+	hypothetical protein	NA	NA	NA	NA
WP_012367233.1\|63493_64891_-	replication initiation protein	NA	NA	NA	NA
WP_012367234.1\|65688_66897_+	AAA family ATPase	A0A240F4U1	Ochrobactrum_phage	9.4e-27	24.9
WP_012367235.1\|66893_67868_+	ParB/RepB/Spo0J family partition protein	S5VTK0	Leptospira_phage	9.9e-11	34.1
WP_012367236.1\|68347_70480_-\|integrase	tyrosine-type recombinase/integrase	NA	NA	NA	NA
WP_012367238.1\|71815_72229_+	type II toxin-antitoxin system HicB family antitoxin	A0A0A8JBA5	Ralstonia_phage	3.6e-23	56.6
WP_012367239.1\|72929_73955_+\|transposase	IS110 family transposase	NA	NA	NA	NA
WP_041490335.1\|78278_78467_+	hypothetical protein	NA	NA	NA	NA
WP_041490378.1\|79353_80016_+\|transposase	IS30 family transposase	W5R8L2	Staphylococcus_phage	4.3e-26	34.3
WP_012367243.1\|80049_80940_+\|transposase	IS3 family transposase	A0A0P0I4A4	Acinetobacter_phage	9.2e-56	38.5
WP_012367244.1\|80977_82312_-	hypothetical protein	NA	NA	NA	NA
81016:81032	attL	NA	NA	NA	NA
WP_012367245.1\|82870_83692_+	hypothetical protein	NA	NA	NA	NA
WP_012367246.1\|83675_84632_+	nucleotidyl transferase AbiEii/AbiGii toxin family protein	NA	NA	NA	NA
WP_050772614.1\|84941_85067_+	hypothetical protein	NA	NA	NA	NA
WP_012367250.1\|87163_88792_+\|integrase,transposase	DDE-type integrase/transposase/recombinase	NA	NA	NA	NA
91395:91411	attR	NA	NA	NA	NA

DBSCAN-SWA_2

100887 : 159879

Hokovirus(33.33%)

transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_012367263.1\|100887_101079_-\|transposase	IS3 family transposase	NA	NA	NA	NA
WP_012367264.1\|101182_101761_-	recombinase family protein	A0A0A7NPV4	Enterobacteria_phage	1.5e-35	52.9
WP_041490337.1\|102130_102358_+	hypothetical protein	NA	NA	NA	NA
WP_041490338.1\|103466_103754_-	hypothetical protein	NA	NA	NA	NA
WP_041490386.1\|103781_103886_-	hypothetical protein	NA	NA	NA	NA
WP_050772605.1\|104408_104870_-	hypothetical protein	NA	NA	NA	NA
WP_041490339.1\|104921_105041_-	hypothetical protein	NA	NA	NA	NA
WP_012367265.1\|105548_106052_-	hypothetical protein	NA	NA	NA	NA
WP_041490340.1\|106079_106193_-	hypothetical protein	NA	NA	NA	NA
WP_012367266.1\|106748_108068_-	hypothetical protein	NA	NA	NA	NA
WP_050772606.1\|108126_109515_+	hemagglutinin	NA	NA	NA	NA
WP_041490389.1\|109641_110346_+	OmpA family protein	NA	NA	NA	NA
WP_041490341.1\|110999_111305_+	H-NS histone family protein	NA	NA	NA	NA
WP_041490342.1\|111401_111749_+	hypothetical protein	NA	NA	NA	NA
WP_041490343.1\|111784_112930_+	DUF2827 domain-containing protein	NA	NA	NA	NA
WP_012367272.1\|112944_114093_+	DUF2827 domain-containing protein	NA	NA	NA	NA
WP_012367273.1\|114133_114595_+	DUF4019 domain-containing protein	NA	NA	NA	NA
WP_012367274.1\|114676_115039_+\|transposase	transposase	NA	NA	NA	NA
WP_050772607.1\|116394_117687_+	hypothetical protein	NA	NA	NA	NA
WP_012367277.1\|118136_119972_+	tetratricopeptide repeat protein	NA	NA	NA	NA
WP_050772608.1\|122474_122945_-	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_012367281.1\|123235_124510_+	hypothetical protein	NA	NA	NA	NA
WP_012367282.1\|124568_124916_-	hypothetical protein	NA	NA	NA	NA
WP_012367283.1\|125443_126262_-	FkbM family methyltransferase	NA	NA	NA	NA
WP_012367284.1\|126467_127064_+	resolvase	A0A219YA40	Aeromonas_phage	3.9e-34	47.0
WP_012367285.1\|127068_128190_+\|transposase	IS481 family transposase	NA	NA	NA	NA
WP_012367286.1\|128547_129096_+	type 1 fimbrial protein	NA	NA	NA	NA
WP_012367287.1\|129175_129928_+	fimbria/pilus periplasmic chaperone	NA	NA	NA	NA
WP_012367288.1\|130036_132691_+	fimbrial biogenesis outer membrane usher protein	NA	NA	NA	NA
WP_050772610.1\|132687_133701_+\|transposase	transposase	H7BW94	unidentified_phage	5.3e-07	27.9
WP_041490398.1\|136197_136860_+\|transposase	IS30 family transposase	W5R8L2	Staphylococcus_phage	2.5e-26	34.3
WP_012367292.1\|137465_138287_+	fimbrial protein TcfA	NA	NA	NA	NA
WP_012367293.1\|138290_138791_+	Cro/Cl family transcriptional regulator	NA	NA	NA	NA
WP_012367294.1\|138869_141572_+	outermembrane fimbrial usher protein	NA	NA	NA	NA
WP_041490345.1\|141646_142807_+	minor pilin and initiator	NA	NA	NA	NA
WP_012367297.1\|147093_147945_+	DUF1460 domain-containing protein	NA	NA	NA	NA
WP_012367298.1\|148869_149586_-	response regulator transcription factor	NA	NA	NA	NA
WP_012367299.1\|149978_152468_+	response regulator	A0A1V0SGX0	Hokovirus	4.3e-34	27.3
WP_041490346.1\|152522_154655_-	response regulator	A0A1V0SGX0	Hokovirus	1.8e-28	28.7
WP_050772611.1\|158118_158796_+	response regulator transcription factor	NA	NA	NA	NA
WP_012367302.1\|159612_159879_-\|transposase	transposase	NA	NA	NA	NA

DBSCAN-SWA_3

192402 : 242668

Enterobacteria_phage(25.0%)

plate,integrase

attL 196984:196999|attR 253461:253476

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_012367326.1\|192402_193464_-\|plate	type VI secretion system baseplate subunit TssG	NA	NA	NA	NA
WP_012367327.1\|193467_195348_-\|plate	type VI secretion system baseplate subunit TssF	NA	NA	NA	NA
WP_012367328.1\|195349_195871_-\|plate	type VI secretion system baseplate subunit TssE	NA	NA	NA	NA
WP_012367329.1\|195854_196715_-	virulence protein SciE type	NA	NA	NA	NA
WP_063822758.1\|196695_197625_-	TagK domain-containing protein	NA	NA	NA	NA
196984:196999	attL	NA	NA	NA	NA
WP_012367331.1\|198228_200898_+	type VI secretion system ATPase TssH	H6X3M6	Enterobacteria_phage	1.8e-86	32.2
WP_041490350.1\|201064_201244_+	hypothetical protein	NA	NA	NA	NA
WP_012367332.1\|202459_202663_-	hypothetical protein	NA	NA	NA	NA
WP_006752201.1\|202907_203204_-	H-NS histone family protein	NA	NA	NA	NA
WP_012367334.1\|203942_204506_-	N-acetyltransferase	NA	NA	NA	NA
WP_041490351.1\|204502_204820_-	hypothetical protein	NA	NA	NA	NA
WP_041490352.1\|205117_205516_-	hypothetical protein	NA	NA	NA	NA
WP_012367336.1\|205685_206924_-	dicarboxylate/amino acid:cation symporter	NA	NA	NA	NA
WP_012367337.1\|206907_207570_-	GntR family transcriptional regulator	NA	NA	NA	NA
WP_012367338.1\|207720_208185_+	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_012367339.1\|208987_209893_-	hypothetical protein	NA	NA	NA	NA
WP_063822757.1\|210225_210954_-	hypothetical protein	NA	NA	NA	NA
WP_012367342.1\|211033_211288_-	hypothetical protein	NA	NA	NA	NA
WP_012367343.1\|211485_212616_-	HNH endonuclease	NA	NA	NA	NA
WP_012367344.1\|212687_213113_-	hypothetical protein	A0A1X9SGN6	Bradyrhizobium_phage	1.6e-26	47.4
WP_012367345.1\|213419_213638_+	hypothetical protein	NA	NA	NA	NA
WP_041490354.1\|214123_214309_-	hypothetical protein	NA	NA	NA	NA
WP_041490355.1\|215177_215363_-	hypothetical protein	NA	NA	NA	NA
WP_041490356.1\|215473_215764_+	hypothetical protein	NA	NA	NA	NA
WP_041490357.1\|216036_216291_+	hypothetical protein	NA	NA	NA	NA
WP_041490358.1\|216292_216640_-	hypothetical protein	NA	NA	NA	NA
WP_041490359.1\|216686_217016_-	hypothetical protein	NA	NA	NA	NA
WP_012367351.1\|217239_217491_-	hypothetical protein	NA	NA	NA	NA
WP_012367352.1\|217533_217782_-	hypothetical protein	NA	NA	NA	NA
WP_012367353.1\|217794_218277_-	hypothetical protein	NA	NA	NA	NA
WP_012367354.1\|218527_218752_-	hypothetical protein	NA	NA	NA	NA
WP_012367372.1\|219867_220218_-	hypothetical protein	NA	NA	NA	NA
WP_041490360.1\|220684_221065_-	hypothetical protein	NA	NA	NA	NA
WP_012367362.1\|221702_222047_-	hypothetical protein	NA	NA	NA	NA
WP_012367363.1\|222184_222427_-	hypothetical protein	NA	NA	NA	NA
WP_012367364.1\|222439_222859_-	DUF2513 domain-containing protein	NA	NA	NA	NA
WP_012367365.1\|222883_223336_-	hypothetical protein	NA	NA	NA	NA
WP_012367366.1\|223442_224180_-	hypothetical protein	NA	NA	NA	NA
WP_012367367.1\|224235_224565_-	hypothetical protein	NA	NA	NA	NA
WP_012367368.1\|224592_225567_-	hypothetical protein	NA	NA	NA	NA
WP_041490361.1\|225580_225949_-	hypothetical protein	NA	NA	NA	NA
WP_041490362.1\|226111_226930_-	abortive infection family protein	NA	NA	NA	NA
WP_012367371.1\|226947_227394_-	hypothetical protein	NA	NA	NA	NA
WP_012367372.1\|228526_228877_-	hypothetical protein	NA	NA	NA	NA
WP_012367374.1\|229121_229442_-	type II toxin-antitoxin system PemK/MazF family toxin	NA	NA	NA	NA
WP_041490363.1\|229435_229684_-	antitoxin	NA	NA	NA	NA
WP_041490364.1\|229771_230461_-\|integrase	site-specific integrase	A0A1W6DWU1	Sphingobium_phage	1.7e-12	29.4
WP_012367377.1\|230633_230960_+	H-NS histone family protein	NA	NA	NA	NA
WP_012367378.1\|231087_231879_+	DUF159 family protein	NA	NA	NA	NA
WP_012367380.1\|232640_233528_-	ImmA/IrrE family metallo-endopeptidase	NA	NA	NA	NA
WP_012367381.1\|233531_233879_-	helix-turn-helix transcriptional regulator	D2XQ11	Bacillus_virus	2.8e-08	30.6
WP_012367382.1\|233980_234946_+	nucleotidyltransferase	NA	NA	NA	NA
WP_012367383.1\|234956_235469_+	hypothetical protein	NA	NA	NA	NA
WP_012367384.1\|235468_236404_+	AAA family ATPase	NA	NA	NA	NA
WP_012367385.1\|236400_237129_+	hypothetical protein	NA	NA	NA	NA
WP_063822759.1\|237187_237529_-	hypothetical protein	NA	NA	NA	NA
WP_012367387.1\|237624_239577_-\|integrase	tyrosine-type recombinase/integrase	NA	NA	NA	NA
WP_012367388.1\|239573_241475_-	hypothetical protein	NA	NA	NA	NA
WP_012367389.1\|241489_242668_-\|integrase	site-specific integrase	NA	NA	NA	NA
253461:253476	attR	NA	NA	NA	NA

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

3. NC_010551

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Crispr_ID: NC_010551_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_010551_1

595251-595345

Orphan

Consensus_repeat	Method
CGCGTTGCCCGCGACCGCGCCGA	CRISPRCasFinder

1 spacers

The CRISPR arrays of NC_010551_1

>merge|NC_010551|1|595251-595345|CRISPRCasFinder
CGCGTTGCCCGCGACCGCGCCGACGAGGCCGCCCGCGATGGCCGTCAGGATCGACCCCTTGCCGCCGCCGATCGCGCTGCCCGCGACCGCGCCGA

>NC_010551|1|1|595251-595345|CRISPRCasFinder
CGCGTTGCCCGCGACCGCGCCGA	CGAGGCCGCCCGCGATGGCCGTCAGGATCGACCCCTTGCCGCCGCCGAT
CGCGCTGCCCGCGACCGCGCCGA

Protein	Signature genes	Signature genes Name	Protein_function
NC_010551.1\|WP_011655915.1\|592553_593765_+\|ribonucleotide-diphosphate-reductase-subunit-beta	unknown	unknown	gnl\|CDD\|235968
NC_010551.1\|WP_050772513.1\|594178_594898_-\|hypothetical-protein	unknown	unknown	unknown
NC_010551.1\|WP_012363046.1\|595581_596520_-\|carbohydrate-kinase-family-protein	unknown	unknown	gnl\|CDD\|238917
NC_010551.1\|WP_012363051.1\|602748_603393_-\|UDP-N-acetylmuramate--alanine-ligase	unknown	unknown	unknown
NC_010551.1\|WP_012363043.1\|587827_588142_+\|hypothetical-protein	unknown	unknown	unknown
NC_010551.1\|WP_006756843.1\|584817_585369_-\|hypoxanthine-guanine-phosphoribosyltransferase	unknown	unknown	gnl\|CDD\|181675
NC_010551.1\|WP_011655924.1\|603616_605002_+\|UDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl--meso-diaminopimelate-ligase	unknown	unknown	gnl\|CDD\|130153
NC_010551.1\|WP_012363049.1\|600996_601473_-\|acetyl-CoA-carboxylase-biotin-carboxyl-carrier-protein	unknown	unknown	gnl\|CDD\|235777
NC_010551.1\|WP_006752240.1\|585463_586831_-\|signal-recognition-particle-protein	unknown	unknown	gnl\|CDD\|236780
NC_010551.1\|WP_012363045.1\|589194_592194_+\|ribonucleoside-diphosphate-reductase-subunit-alpha	unknown	unknown	gnl\|CDD\|235966
NC_010551.1\|WP_006758913.1\|596613_597117_-\|thiol-peroxidase	unknown	unknown	gnl\|CDD\|179055
NC_010551.1\|WP_006752252.1\|599543_600911_-\|acetyl-CoA-carboxylase-biotin-carboxylase-subunit	unknown	unknown	gnl\|CDD\|236307
NC_010551.1\|WP_041489758.1\|602186_602741_-\|redoxin-family-protein	unknown	unknown	gnl\|CDD\|239264
NC_010551.1\|WP_011655911.1\|586920_587814_+\|ABC-transporter-permease	unknown	unknown	gnl\|CDD\|226621
NC_010551.1\|WP_012363042.1\|584119_584722_+\|MarC-family-protein	unknown	unknown	gnl\|CDD\|170674
NC_010551.1\|WP_012363044.1\|588138_588729_+\|1,6-anhydro-N-acetylmuramyl-L-alanine-amidase-AmpD	unknown	unknown	gnl\|CDD\|236984
NC_010551.1\|WP_012363048.1\|598638_599541_-\|50S-ribosomal-protein-L11-methyltransferase	unknown	unknown	gnl\|CDD\|234786
NC_010551.1\|WP_012363047.1\|597189_598593_-\|DUF3426-domain-containing-protein	unknown	unknown	gnl\|CDD\|378759
NC_010551.1\|WP_012363041.1\|582361_584098_+\|proline--tRNA-ligase	unknown	unknown	gnl\|CDD\|236405
NC_010551.1\|WP_006756005.1\|601539_601992_-\|type-II-3-dehydroquinate-dehydratase	unknown	unknown	gnl\|CDD\|235443

Protein	Function_ID	Function_description	E-value
NC_010551.1\|WP_011655915.1\|592553_593765_+\|ribonucleotide-diphosphate-reductase-subunit-beta	gnl\|CDD\|235968	PRK07209, PRK07209, ribonucleotide-diphosphate reductase subunit beta; Validated.	0
NC_010551.1\|WP_011655911.1\|586920_587814_+\|ABC-transporter-permease	gnl\|CDD\|226621	COG4137, COG4137, ABC-type uncharacterized transport system, permease component [General function prediction only].	5.89301e-61
NC_010551.1\|WP_012363046.1\|595581_596520_-\|carbohydrate-kinase-family-protein	gnl\|CDD\|238917	cd01942, ribokinase_group_A, Ribokinase-like subgroup A. Found in bacteria and archaea, this subgroup is part of the ribokinase/pfkB superfamily. Its oligomerization state is unknown at this time.	1.22584e-98
NC_010551.1\|WP_006756005.1\|601539_601992_-\|type-II-3-dehydroquinate-dehydratase	gnl\|CDD\|235443	PRK05395, PRK05395, type II 3-dehydroquinate dehydratase.	7.76942e-96
NC_010551.1\|WP_006756843.1\|584817_585369_-\|hypoxanthine-guanine-phosphoribosyltransferase	gnl\|CDD\|181675	PRK09162, PRK09162, hypoxanthine-guanine phosphoribosyltransferase; Provisional.	2.8014e-113
NC_010551.1\|WP_011655924.1\|603616_605002_+\|UDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl--meso-diaminopimelate-ligase	gnl\|CDD\|130153	TIGR01081, mpl, UDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl-meso-diaminopimelate ligase. Alternate name: murein tripeptide ligase [Cell envelope, Biosynthesis and degradation of murein sacculus and peptidoglycan].	0
NC_010551.1\|WP_012363049.1\|600996_601473_-\|acetyl-CoA-carboxylase-biotin-carboxyl-carrier-protein	gnl\|CDD\|235777	PRK06302, PRK06302, acetyl-CoA carboxylase biotin carboxyl carrier protein.	3.98737e-84
NC_010551.1\|WP_006752240.1\|585463_586831_-\|signal-recognition-particle-protein	gnl\|CDD\|236780	PRK10867, PRK10867, signal recognition particle protein; Provisional.	0
NC_010551.1\|WP_012363045.1\|589194_592194_+\|ribonucleoside-diphosphate-reductase-subunit-alpha	gnl\|CDD\|235966	PRK07207, PRK07207, ribonucleoside-diphosphate reductase subunit alpha.	0
NC_010551.1\|WP_006758913.1\|596613_597117_-\|thiol-peroxidase	gnl\|CDD\|179055	PRK00522, tpx, thiol peroxidase.	1.09654e-95
NC_010551.1\|WP_006752252.1\|599543_600911_-\|acetyl-CoA-carboxylase-biotin-carboxylase-subunit	gnl\|CDD\|236307	PRK08591, PRK08591, acetyl-CoA carboxylase biotin carboxylase subunit; Validated.	0
NC_010551.1\|WP_041489758.1\|602186_602741_-\|redoxin-family-protein	gnl\|CDD\|239264	cd02966, TlpA_like_family, TlpA-like family; composed of TlpA, ResA, DsbE and similar proteins. TlpA, ResA and DsbE are bacterial protein disulfide reductases with important roles in cytochrome maturation. They are membrane-anchored proteins with a soluble TRX domain containing a CXXC motif located in the periplasm. The TRX domains of this family contain an insert, approximately 25 residues in length, which correspond to an extra alpha helix and a beta strand when compared with TRX. TlpA catalyzes an essential reaction in the biogenesis of cytochrome aa3, while ResA and DsbE are essential proteins in cytochrome c maturation. Also included in this family are proteins containing a TlpA-like TRX domain with domain architectures similar to E. coli DipZ protein, and the N-terminal TRX domain of PilB protein from Neisseria which acts as a disulfide reductase that can recylce methionine sulfoxide reductases.	1.41224e-41
NC_010551.1\|WP_012363042.1\|584119_584722_+\|MarC-family-protein	gnl\|CDD\|170674	PRK10739, PRK10739, YhgN family NAAT transporter.	1.84757e-49
NC_010551.1\|WP_012363044.1\|588138_588729_+\|1,6-anhydro-N-acetylmuramyl-L-alanine-amidase-AmpD	gnl\|CDD\|236984	PRK11789, PRK11789, 1,6-anhydro-N-acetylmuramyl-L-alanine amidase AmpD.	1.7489e-122
NC_010551.1\|WP_012363048.1\|598638_599541_-\|50S-ribosomal-protein-L11-methyltransferase	gnl\|CDD\|234786	PRK00517, prmA, 50S ribosomal protein L11 methyltransferase.	8.83026e-122
NC_010551.1\|WP_012363047.1\|597189_598593_-\|DUF3426-domain-containing-protein	gnl\|CDD\|378759	pfam11906, DUF3426, Protein of unknown function (DUF3426). This family of proteins are functionally uncharacterized. This protein is found in bacteria. Proteins in this family are typically between 262 to 463 amino acids in length.	3.0768e-40
NC_010551.1\|WP_012363041.1\|582361_584098_+\|proline--tRNA-ligase	gnl\|CDD\|236405	PRK09194, PRK09194, prolyl-tRNA synthetase; Provisional.	0

>NC_010551.1|WP_050772513.1|594178_594898_-|hypothetical-protein
MSVRVVLASRDYGRLPVGNGHAAAGLSAVFTPDAGATDAVDAVVAGAAFFTTAFFGAAAFFAGAAAFGAAAFFAGAAFLAGAAFFAAAFFAGAAFLAAAFFAGAAFFAAAFFAGAAFFAATFFVATFLAATFFAAAFFAGAAFFAATFFTATFLAATFLAATFFVATFLAATFFAAAFFAGAAFFAATFFTATFFAATFFTAAAFLAGAAFFATVFLAATFFAAGFFLAVAMLFSFRFR
>NC_010551.1|WP_011655915.1|592553_593765_+|ribonucleotide-diphosphate-reductase-subunit-beta
MLNWDDEKTAVTPASGAQQNALRTSAGMAVGLQATAPAAHQVRDIFEGDLAVPPQASAVPAAGSEARVNVADKRIINGQTDVNQLVPFKYKWAWEKYLAGCANHWMPQEINMSRDIALWKDPNGLTEDERRIVKRNLGFFVTADSLAANNIVLGTYRHITAPECRQFLLRQAFEEAIHTHAYQYIVESLGLDEGEIFNAYHEVTSIRAKDEFLIPFIHTLTDPAFKTGTLEADQKLLKSLIVFACIMEGLFFYVGFTQILALGRQNKMTGAAEQYQYILRDESMHCNFGIDLINQIKLENPHLWTAEFRAEIRELFKQAVELEYRYAEDTMPRGVLGLNASMFKSYLRFISNRRCQQIGLDPLYPNEENPFPWMSEMIDLKKERNFFETRVIEYQTGGALSWE
>NC_010551.1|WP_012363045.1|589194_592194_+|ribonucleoside-diphosphate-reductase-subunit-alpha
MQTTDNATSQYESASSRPLGGTEQGAKALAPQATFADYKVIRRNGSVVSFEPSKIAIAVTKAFLAVNGGQGAASARVREQVEQLTHSVVRALVRSRPNGGTFHIEDIQDQVELALMRGGEHNVARAYVLYREKRHLERQHAGEEAAAAGGEASAGINVVDNGVTRPLDMNALRELIVSACAGLGAAVNPEPIVAETVKNLYDGVPMSQVYDSAILAARTMIEKDPAYSQVTARILLHTIRREILGEEVLQAEMATRYTEYFPQFLKRGVDAGLLDDKLLQFDLKRLGEALDANRDLQFGYLGLQTLYDRYFLHVEGTRIEMPQAFFMRVAMGLSLNEIDRETRAIEFYNVLSSFDFMSSTPTLFNSGTHRSQLSSCYLTTVADDLDGIYEALKENALLSKFAGGLGNDWTRVRALGSHIKGTNGKSQGVVPFLKVVNDTAVAVNQGGKRKGAVCAYLESWHLDIEEFLELRKNTGDDRRRTHDMNTANWIPDLFMKRVMEGADWTLFSPSTCPDLHDKFGAEFEAAYTAYEDKVARGEIKLFKKIPAQQLWRKMLGMLFETGHPWITFKDPCNVRSPQQHVGVVHSSNLCTEITLNTSDTEIAVCNLGSVNLVAHLVKQADGSYALDQDKLKRTISVAMRMLDNVIDINYYAVPKARNSNLKHRPVGMGIMGFQDCLHLLRTPYASEAAVEFADRSMEAVCYYAYYASTELAEERGRYSSYRGSLWDRGILPQDTLKLLTEARGGYVEVDTSESLDWTTLRSRIAAHGMRNSNCVAIAPTATISNIIGVSACIEPTFQNLYVKSNLSGEFTVVNEYLVRDLKERGLWDEVMVADLKYFDGMLSRIDRIPADLRAIYATAFEVDPTWLVEAASRRQKWIDQAQSLNIYMGGASGKKLDEVYKLAWLRGLKTTYYLRTMAATHVEKSTVAHGALNAVPTGGAGGSSSGGAQGAAGGFGAAGGDASSGAVNAAAALAPVEADGPVCTMRPGDAGFDECEACQ
>NC_010551.1|WP_012363044.1|588138_588729_+|1,6-anhydro-N-acetylmuramyl-L-alanine-amidase-AmpD
MSDAAPLSVDAHGWVREARHAPSPNFEARPAGAVPTLVVVHNISLPPGEFGGDAIESLFLNRLDCDAHPYYQSHLRGVRVSAHFLIRRDGELVQFVSCDERAWHAGSSEFFGRPRCNDFSIGIELEGADDVPFDPAQYATLGVLARTLAARYPIDAVVGHSDVAPGRKTDPGPHFDWQRFAGDAGFSAEYFPFRQH
>NC_010551.1|WP_012363043.1|587827_588142_+|hypothetical-protein
MRQILLLILLLFAGSWLARKLRQAQEQAQARTGRGNGADAPGHGGAGAARPNGATRSLPEPMVRCAECGVHAPKGDAVAAGGEYFCSTDHARRHGARASGHDAR
>NC_010551.1|WP_011655911.1|586920_587814_+|ABC-transporter-permease
MDIVLYALTAFLYGGLAVAGWRTHRQGATPLVASVPAVPVPASAASGMSAAGRALLFAALVAHGVLLHMTIFPHDAMIFGFAFALSAMFWLGAGIYWIESFFFPLDSLRLLVLPLACGASLLPLVFGGVRVLPYAAAPLFKMHFLIANIAYGLFAIAALHAVLMLMVERRLQSLRSGGRDGSTGWIASWLETLPPLLTLEKLLFRLIGAGFVLLTLTLASGILFSEQVDARAMRLDHKTVFAVLSWLMFGGLLVARKTSGWRGRGAARWVLVSFAALLLAYVGSRFVFEVLLHRSVV
>NC_010551.1|WP_006752240.1|585463_586831_-|signal-recognition-particle-protein
MLDNLTQRMARVVKTLRGEARLTEANTQEMLREVRLALLEADVALPVVREFIAKVKEKALGEEVISSLSPGQALVGVVQKELTAVIGGDYEGKAAELNLAVTPPAVILMAGLQGAGKTTTVGKLAKLLREKHKKKVLTVSCDVYRPAAIMQLKTVSEQVGADFFPSTPDQKPVDIAVAAVDWAKRHYHDVLIVDTAGRLGIDEAMMQEIAALHGTLKPAETLFVVDAMLGQDAVNTAKAFNDTLPLTGVVLTKLDGDSRGGAALSVRHITGKPIKFVGVAEKLDGLEVFHPDRMANRILGMGDILALVEEAQRGVDVQAAQKLADKVKKGGDFDLNDFRAQISQMKNMGGLSSLMDKLPAQFQQAAAGADMGQAEKSIRRMEGIISSMTPAERAKPEIIKATRKRRIAAGAGVPVQEVNRMLNQYDQMRTMMKKLKGGNMQKMMRGLKGMMPGMR
>NC_010551.1|WP_006756843.1|584817_585369_-|hypoxanthine-guanine-phosphoribosyltransferase
MNREEALHIFDHSEEIVSADAVNASISRMADAIRAEIGDAFPLVLSVMGGAAVFTGMLLPRLDFPLEFDYIHLTRYRNTTQGSPEMHWRVAPRESVKDRIVLVLDDILDEGETMAAIRDRILDMGATRFMSAVLCEKTLAKAKPLHPDFCGFPVPDRYVFGCGMDAKGYWRNLPTIRALTANV
>NC_010551.1|WP_012363042.1|584119_584722_+|MarC-family-protein
MEYTFLSATVLLVLITDPLGNIPLFITAMRDVPRERRVKLILREVGIAFVILLFFMVVGDRFLRMMSLTDLSLRLGGGIVLFLIALRMIFPHPDGALGSDPRAGGEPFIVPLAIPALAGPSALATVMLLTSQAPGKMFEWVGALTVTMIVCAITLVLAERIQQWLGERTVAAFERLMGLVLVAISVEMLLAGIRAFVHQL
>NC_010551.1|WP_012363041.1|582361_584098_+|proline--tRNA-ligase
MKASRFFIGTLKEAPADAEIVSHKLMVRAGMIRRVAGGIYNYLPVGLRSIRKVEAIVREEMNRAGAIELLMPAVQPAELWQESGRWEQYGPELLRFKDRKDNDFVIGPTHEEVVTDIARNQIKSYRQMPVNFYQIQTKFRDEIRPRFGVMRGREFIMKDAYSFDKDTAGLNESYRKMYDAYVRIFTRLGLEFRAVAADSGSIGGNFSHEFHVIADTGEDAIAYCPTSDFAANIEAAEALPLIAARAAPAEAMEKVATPGKAKCEAVAELLAIPLERTIKSIVLATENEGAEPTIWLIMLRGDHDLNEIKVSKLPGLKNHRFATEQEIVDWFGTPPGYLGPVGTKKPVKVIADRTVANMSDFVVGANEVDYHIAGVNWGRDLPEPEVADVRDVKKGDPSPDGKGTIDICRGIEVGHVFQLGTKYSEAMGATFLDESGKPQPMLMGCYGVGVTRILGAAIEQNFDDRGIIWPESIAPFEVVLCPMGYDRSDMVREAADKLYAELAAAGIDVILDDRGERPGVMFADWELIGVPHRLVIGERGLKEGKIEYQGRRDAEATLLPADEAAATVTEKIRAALAH
>NC_010551.1|WP_012363046.1|595581_596520_-|carbohydrate-kinase-family-protein
MTTLICGSLAYDNIMTFEGRFREHILPDQVHLLNVSFLVPTMRREFGGCAGNIAYALHMLGGDARIMATVGANDADRYLERLDSLGLSKASVRVVPETHTAQAMITTDLDNNQITAFHPGAMMVSHLNRADEVAGVKLGIVAPDGFDGMVQHAEQFAKAGVPFVFDPGQGLPLFDGATLRRIIELATFVAVNDYEGKLVSDKTGWSEQDIASRVQALIITRGEHGSTILHKNGEEQIPVVQAERVVDPTGCGDAFRGGLLYGIENGLDWATTGRLASLMGSIKIAHQGPQTYALTRAEIDARFEAAFGYSLK
>NC_010551.1|WP_006758913.1|596613_597117_-|thiol-peroxidase
MSKVTLGGNPIDLAGTFPAVGSQAPDFKLVGKDLADLSLASFAGKRKVLNIVPSLDTPTCATSTRKFNEAASSLDNTVVVVVSGDLPFAATRFCTTEGLANVVTASTFRGGRAFANAYGVDVTSGPLNGLTARAVVVLDAQDKVIHAQLVDEIKDEPNYDAALAALK
>NC_010551.1|WP_012363047.1|597189_598593_-|DUF3426-domain-containing-protein
MLLATRCPHCETVFRLQQEQLSLHDGLVRCGHCQQVFNASQSLVPDPARQPDPALTEAAPAGPHAAAPQPDAAPPRLFATDAPVEPASDIDYKPEGWDMWAPWLDAGVDPSLQHTVQTVRAKPLVPLALPAMEAGVVRLSGTPAPIASVPAELHAAHTQAAEPDATLHETDASGTSFAAPTAEPGLREPRFVAHTPSAEPAAAEPAEPVGNARFAVPDDEHAPREPRFAFRPAQAESAPESGPDIHADERAPAPTAAASEPAAEPDIQPAVQPVVQPAIPFPAALTDDDRPHFAVTRETRETGAPQRRGMLGGFFGGLVAAALVVLLVAQLAWWQRETVMIYWPATQGWFRQACVPLGCRLTPPRAIDGLRLDATDLRQIDGPRTLELKVPLTNRYRVALAYPSLELTLLDDTNHVTVRRVLAPRDYVRPGTPIDAGLPPGTTQTMVVRLDTNGTPASNFRVQIFYP
>NC_010551.1|WP_012363048.1|598638_599541_-|50S-ribosomal-protein-L11-methyltransferase
MSYRELVVELAREHAEALSDALLELGALSVSVEDADADTPDEQPLFGEPGLVPDRTAWQHSRVIALLSPDHEPAVLLAAAVNDIGVTETPKFDVREVEEQDWVRLTQSQFEPIPIGERIWVVPSWHDAPDPDALILELDPGLAFGTGSHPTTRLCMEWLEQSVKPGQSVLDYGCGSGILAILARKCGANPVVGIDIDPQAVESARQNSERNHAEVTYGLPDACPAGEFDIVVANILSNPLKLMASMLASKVKPGGRIALSGVLARQADEVAAVYARYVDISVWREHEGWVCLAGTRRESH
>NC_010551.1|WP_006752252.1|599543_600911_-|acetyl-CoA-carboxylase-biotin-carboxylase-subunit
MFEKILIANRGEIALRIQRACRELGVKTVVVYSEADKEAKYVRLADEAVCIGPAPSNLSYLNMPALISAAEVTDAEAIHPGYGFLSENADFAERVEQSGFTFIGPRPETIRMMGDKVTAKQTMIKTGVPCVPGSEGALPDDPKEIVKIARTIGYPVIIKAAGGGGGRGMRVVHTEAALVNAVNMTREEAGRAFGNPQVYMEKFLENPRHIEIQVLSDAHKNAIWLGERDCSMQRRHQKVIEEAPAPGIPRRLIERIGDRCADACKKMGYLGAGTFEFLYENNEFYFIEMNTRVQVEHPVSEMITGVDIVQEQIRIAAGEKIALRQRDIQFRGHAIECRINAEDPFKFTPSPGRITSWHTPGGPGVRVDSHAYNGYFVPPNYDSMIGKLITYGATRDQAIRRMRIALSEMVVEGIHTNIPLHRELMIDSKFVEGGTSIHYLEHRLAQKQQVAPEEA
>NC_010551.1|WP_012363049.1|600996_601473_-|acetyl-CoA-carboxylase-biotin-carboxyl-carrier-protein
MDLRKLKTLIDLVSESGISELEVTEGEGKVRIVKNAPPVYVQQTAGFAPQVSAPAPSAALPTDGAAAPAAGAAAAAPAVPQGHVVTSPMVGTFYRAPSPGADPFVQVGDTVKEGQTICIIEAMKLLNEIESDKAGVVKEILVENGQAVEYGQPLFVIG
>NC_010551.1|WP_006756005.1|601539_601992_-|type-II-3-dehydroquinate-dehydratase
MTRLLVLHGPNLNLLGTREPEVYGRVTLAQIDQALAARAQEAGAELSSFQSNHEGALVDRIQAAREEQTDFILINPAAYTHTSVAIRDAIAGVGIPFVEIHLSNVHRREAFRHHSYFSDQAEGVICGLGWKGYLYALEYALDKLQGASRG
>NC_010551.1|WP_041489758.1|602186_602741_-|redoxin-family-protein
MMTKRMLALAVVAAAAVAGGLAAGHWFRGGSADDGIAVAAPAAQGNPVDQLWAASLTSVDGKPASLAAFKGQKVVVNFWASWCGPCVEEMPELVALSHQYKQKGVRFIGIGVDSDQNVKNFLQKVKVDYPVFVSGYAGADLARNFGNTAGALPFTVVIDETGKIRETKLGQIQPAELRKTLDAL
>NC_010551.1|WP_012363051.1|602748_603393_-|UDP-N-acetylmuramate--alanine-ligase
MSRKPLVDPRRAREEIAQSAARLIAEDGLDYASAKRKAARQLFGDTRVAGEWLPDNDLIEEELREYLALFQSDTQPDELRRLRELALDWMRRLAEFNPYVTGAVLHGTANEHSDIHLQIFTDNPKDVAIYLLNQNVQYDVSETRHFAGRADVETLSFLWRPRRDMDAIGIHVALYASDDLRGAVKADARGRVARADATALRALLEASNAPSEPE
>NC_010551.1|WP_011655924.1|603616_605002_+|UDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl--meso-diaminopimelate-ligase
MHIHILGICGTFMGGLAVLAREAGHTVTGCDAGVYPPMSTQLEAQGITLIEGYGAEQIDLKPDLFVIGNVVTRGNPLMEAILDRGLPYVSGPQWLGEHVLAGKWVLAVAGTHGKTTTSSMLAWLLEDAGLNPGFLIGGVPLNFGVSARLTDSSFFVIEADEYDTAFFDKRSKFVHYRPRTAVLNNLEFDHADIFPDLAAIETQFHHLVRTVPGVGRLVTNGRSDALERVLARGCWSEVERFGVDGGWQALPAEDGVPVDERFAVYSQSERVGEVAWQVQGDHNRMNALAAIAAARHVGVPPAQAAESLASFRNVKRRMEVRGSIDGVTVYDDFAHHPTAIETTIAGLRARIGRQNSRILAVLEPRSNTMKLGVMKAQLPASLADADLVFGYGAPAGRDVLGWNLADALAPLGDKARAFDDLHLLVKSVVEAARPGDHVLVMSNGGFGGVHQKLLDALGSRA

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Crispr_ID: NC_010551_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_010551_2

1842393-1842503

Orphan

Consensus_repeat	Method
GGGGTTCAAGGAACGGTAAAGGAGGAACA	CRISPRCasFinder

1 spacers

The CRISPR arrays of NC_010551_2

>merge|NC_010551|2|1842393-1842503|CRISPRCasFinder
GGGGTTCAAGGAACGGTAAAGGAGGAACAGCCTGCGCGACGATGCGCGAGAACGCCGCGCCCTCCGGCGAACGCAAACGGCGGGGGTTCAAGGAAAGGTAAAGGAGGAACA

>NC_010551|2|2|1842393-1842503|CRISPRCasFinder
GGGGTTCAAGGAACGGTAAAGGAGGAACA	GCCTGCGCGACGATGCGCGAGAACGCCGCGCCCTCCGGCGAACGCAAACGGCG
GGGGTTCAAGGAAAGGTAAAGGAGGAACA

Protein	Signature genes	Signature genes Name	Protein_function
NC_010551.1\|WP_012363941.1\|1848087_1849368_-\|MFS-transporter	unknown	unknown	gnl\|CDD\|340877
NC_010551.1\|WP_012363933.1\|1838921_1839899_-\|magnesium/cobalt-transporter-CorA	unknown	unknown	gnl\|CDD\|213364
NC_010551.1\|WP_012363934.1\|1840079_1840226_+\|cytochrome-bd-I-oxidase-subunit-CydX	unknown	unknown	gnl\|CDD\|369733
NC_010551.1\|WP_012363929.1\|1834143_1834608_-\|RidA-family-protein	unknown	unknown	gnl\|CDD\|100006
NC_010551.1\|WP_012363940.1\|1847116_1848082_-\|bifunctional-glyoxylate/hydroxypyruvate-reductase-B	unknown	unknown	gnl\|CDD\|185307
NC_010551.1\|WP_006754794.1\|1849528_1850521_-\|sugar-kinase	unknown	unknown	gnl\|CDD\|238571
NC_010551.1\|WP_012363942.1\|1850549_1851314_-\|TIM-barrel-protein	unknown	unknown	gnl\|CDD\|366542
NC_010551.1\|WP_012363937.1\|1844052_1844484_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|290790
NC_010551.1\|WP_012363928.1\|1833450_1833870_-\|organic-hydroperoxide-resistance-protein	unknown	unknown	gnl\|CDD\|274649
NC_010551.1\|WP_006755038.1\|1838624_1838912_+\|YciI-family-protein	unknown	unknown	gnl\|CDD\|237238
NC_010551.1\|WP_006755037.1\|1837692_1838181_-\|YbaK/EbsC-family-protein	unknown	unknown	gnl\|CDD\|239824
NC_010551.1\|WP_006755043.1\|1842556_1843021_-\|Lrp/AsnC-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|224439
NC_010551.1\|WP_012363930.1\|1834872_1835805_+\|LysR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|176114
NC_010551.1\|WP_012363939.1\|1845750_1846794_-\|LacI-family-DNA-binding-transcriptional-regulator	unknown	unknown	gnl\|CDD\|380506
NC_010551.1\|WP_012363931.1\|1835884_1836592_-\|SDR-family-oxidoreductase	unknown	unknown	gnl\|CDD\|237218
NC_010551.1\|WP_012363936.1\|1843387_1843924_+\|Spy/CpxP-family-protein-refolding-chaperone	unknown	unknown	gnl\|CDD\|369534
NC_010551.1\|WP_006755042.1\|1840940_1842041_-\|NAD(P)H-binding-protein	unknown	unknown	gnl\|CDD\|224662
NC_010551.1\|WP_012363935.1\|1840222_1840840_+\|ATP-binding-protein	unknown	unknown	gnl\|CDD\|379324
NC_010551.1\|WP_011656931.1\|1844532_1844895_-\|DUF3022-domain-containing-protein	unknown	unknown	gnl\|CDD\|378603
NC_010551.1\|WP_012363938.1\|1844907_1845696_-\|YhfC-family-intramembrane-metalloprotease	unknown	unknown	gnl\|CDD\|337619

Protein	Function_ID	Function_description	E-value
NC_010551.1\|WP_012363941.1\|1848087_1849368_-\|MFS-transporter	gnl\|CDD\|340877	cd17319, MFS_ExuT_GudP_like, Hexuronate transporter, Glucarate transporter, and similar transporters of the Major Facilitator Superfamily. This family is composed of predominantly bacterial transporters for hexuronate (ExuT), glucarate (GudP), galactarate (GarP), and galactonate (DgoT). They mediate the uptake of these compounds into the cell. They belong to the Major Facilitator Superfamily (MFS) of membrane transport proteins, which are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	8.37524e-86
NC_010551.1\|WP_012363933.1\|1838921_1839899_-\|magnesium/cobalt-transporter-CorA	gnl\|CDD\|213364	cd12830, MtCorA-like, Mycobacterium tuberculosis CorA-like subfamily. This bacterial subfamily belongs to the Thermotoga maritima CorA (TmCorA)-like family of the MIT superfamily of essential membrane proteins involved in transporting divalent cations (uptake or efflux) across membranes. This subfamily includes the Mg2+ transporter Mycobacterium tuberculosis CorA (which also transports Co2+). Thermotoga maritima CorA forms funnel-shaped homopentamers, the tip of the funnel is formed from two C-terminal transmembrane (TM) helices from each monomer, and the large opening of the funnel from the N-terminal cytoplasmic domains. The GMN signature motif of the MIT superfamily occurs just after TM1, mutation within this motif is known to abolish Mg2+ transport by a related protein, Saccharomyces cerevisiae Alr1p. Natural variants in this signature sequence may be associated with the transport of different divalent cations. The functional diversity of the MIT superfamily may also be due to minor structural differences regulating gating, substrate selection, and transport.	1.58281e-141
NC_010551.1\|WP_012363934.1\|1840079_1840226_+\|cytochrome-bd-I-oxidase-subunit-CydX	gnl\|CDD\|369733	pfam08173, YbgT_YccB, Membrane bound YbgT-like protein. This family contains a set of membrane proteins, typically 33 amino acids long. The family has no known function, but the protein is found in the operon CydAB in E. coli. Members have a consensus motif (MWYFXW) which is rich in aromatic residues. The protein forms a single membrane-spanning helix. This family seems to be restricted to Proteobacteria.	1.08032e-09
NC_010551.1\|WP_012363929.1\|1834143_1834608_-\|RidA-family-protein	gnl\|CDD\|100006	cd02199, YjgF_YER057c_UK114_like_1, This group of proteins belong to a large family of YjgF/YER057c/UK114-like proteins present in bacteria, archaea, and eukaryotes with no definitive function. The conserved domain is similar in structure to chorismate mutase but there is no sequence similarity and no functional connection. Members of this family have been implicated in isoleucine (Yeo7, Ibm1, aldR) and purine (YjgF) biosynthesis, as well as threonine anaerobic degradation (tdcF) and mitochondrial DNA maintenance (Ibm1). This domain homotrimerizes forming a distinct intersubunit cavity that may serve as a small molecule binding site.	3.94212e-61
NC_010551.1\|WP_012363940.1\|1847116_1848082_-\|bifunctional-glyoxylate/hydroxypyruvate-reductase-B	gnl\|CDD\|185307	PRK15409, PRK15409, glyoxylate/hydroxypyruvate reductase GhrB.	2.16385e-162
NC_010551.1\|WP_006754794.1\|1849528_1850521_-\|sugar-kinase	gnl\|CDD\|238571	cd01166, KdgK, 2-keto-3-deoxygluconate kinase (KdgK) phosphorylates 2-keto-3-deoxygluconate (KDG) to form 2-keto-3-deoxy-6-phosphogluconate (KDGP). KDG is the common intermediate product, that allows organisms to channel D-glucuronate and/or D-galacturinate into the glycolysis and therefore use polymers, like pectin and xylan as carbon sources.	2.54437e-97
NC_010551.1\|WP_012363942.1\|1850549_1851314_-\|TIM-barrel-protein	gnl\|CDD\|366542	pfam01261, AP_endonuc_2, Xylose isomerase-like TIM barrel. This TIM alpha/beta barrel structure is found in xylose isomerase and in endonuclease IV (EC:3.1.21.2). This domain is also found in the N termini of bacterial myo-inositol catabolism proteins. These are involved in the myo-inositol catabolism pathway, and is required for growth on myo-inositol in Rhizobium leguminosarum bv. viciae.	3.20298e-06
NC_010551.1\|WP_012363937.1\|1844052_1844484_+\|hypothetical-protein	gnl\|CDD\|290790	pfam14083, PGDYG, PGDYG protein. This family of proteins is functionally uncharacterized. This family of proteins is found in bacteria. Proteins in this family are approximately 150 amino acids in length. There is a conserved PGDYG motif.	1.26877e-54
NC_010551.1\|WP_012363928.1\|1833450_1833870_-\|organic-hydroperoxide-resistance-protein	gnl\|CDD\|274649	TIGR03561, organ_hyd_perox, peroxiredoxin, Ohr subfamily. pfam02566, OsmC-like protein, contains several deeply split clades of homologous proteins. The clade modeled here includes the protein Ohr, or organic hydroperoxide resistance protein. [Cellular processes, Detoxification].	4.0536e-66
NC_010551.1\|WP_006755038.1\|1838624_1838912_+\|YciI-family-protein	gnl\|CDD\|237238	PRK12866, PRK12866, YciI-like protein; Reviewed.	2.44704e-59
NC_010551.1\|WP_006755037.1\|1837692_1838181_-\|YbaK/EbsC-family-protein	gnl\|CDD\|239824	cd04332, YbaK_like, YbaK-like. The YbaK family of deacylase domains includes the INS amino acid-editing domain of the bacterial class II prolyl tRNA synthetase (ProRS), and it's trans-acting homologs, YbaK, ProX, and PrdX. The primary function of INS is to hydrolyze mischarged cysteinyl-tRNA(Pro)'s, thus helping ensure the fidelity of translation. Organisms whose ProRS lacks the INS domain express an INS homolog in trans (e.g. YbaK, ProX, or PrdX).	1.41839e-29
NC_010551.1\|WP_006755043.1\|1842556_1843021_-\|Lrp/AsnC-family-transcriptional-regulator	gnl\|CDD\|224439	COG1522, Lrp, Transcriptional regulators [Transcription].	7.52546e-29
NC_010551.1\|WP_012363930.1\|1834872_1835805_+\|LysR-family-transcriptional-regulator	gnl\|CDD\|176114	cd08422, PBP2_CrgA_like, The C-terminal substrate binding domain of LysR-type transcriptional regulator CrgA and its related homologs, contains the type 2 periplasmic binding domain. This CD includes the substrate binding domain of LysR-type transcriptional regulator (LTTR) CrgA and its related homologs. The LTTRs are acting as both auto-repressors and activators of target promoters, controlling operons involved in a wide variety of cellular processes such as amino acid biosynthesis, CO2 fixation, antibiotic resistance, degradation of aromatic compounds, nodule formation of nitrogen-fixing bacteria, and synthesis of virulence factors, to name a few. In contrast to the tetrameric form of other LTTRs, CrgA from Neisseria meningitides assembles into an octameric ring, which can bind up to four 63-bp DNA oligonucleotides. Phylogenetic cluster analysis further showed that the CrgA-like regulators form a subclass of the LTTRs that function as octamers. The CrgA is an auto-repressor of its own gene and activates the expression of the mdaB gene which coding for an NADPH-quinone reductase and that its action is increased by MBL (alpha-methylene-gamma-butyrolactone), an inducer of NADPH-quinone oxidoreductase. The structural topology of this substrate-binding domain is most similar to that of the type 2 periplasmic binding proteins (PBP2), which are responsible for the uptake of a variety of substrates such as phosphate, sulfate, polysaccharides, lysine/arginine/ornithine, and histidine. The PBP2 bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap. After binding their specific ligand with high affinity, they can interact with a cognate membrane transport complex comprised of two integral membrane domains and two cytoplasmically located ATPase domains. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis.	4.79656e-68
NC_010551.1\|WP_012363939.1\|1845750_1846794_-\|LacI-family-DNA-binding-transcriptional-regulator	gnl\|CDD\|380506	cd06283, PBP1_RegR_EndR_KdgR-like, ligand-binding domain of DNA transcription repressor RegR and other putative regulators such as KdgR and EndR. Ligand-binding domain of DNA transcription repressor RegR and other putative regulators such as KdgR and EndR, all of which are members of the LacI-GalR family of bacterial transcription regulators. RegR regulates bacterial competence and the expression of virulence factors, including hyaluronidase. The LacI-GalR family repressors are composed of two functional domains: an N-terminal HTH (helix-turn-helix) domain, which is responsible for the DNA-binding specificity, and a C-terminal ligand-binding domain, which is homologous to the sugar-binding domain of ABC-type transport systems that contain the type 1 periplasmic binding protein-like fold. As also observed in the periplasmic binding proteins, the C-terminal domain of the bacterial transcription repressor undergoes a conformational change upon ligand binding which in turn changes the DNA binding affinity of the repressor.	3.45503e-91
NC_010551.1\|WP_012363931.1\|1835884_1836592_-\|SDR-family-oxidoreductase	gnl\|CDD\|237218	PRK12825, fabG, 3-ketoacyl-(acyl-carrier-protein) reductase; Provisional.	4.58383e-56
NC_010551.1\|WP_012363936.1\|1843387_1843924_+\|Spy/CpxP-family-protein-refolding-chaperone	gnl\|CDD\|369534	pfam07813, LTXXQ, LTXXQ motif family protein. This protein family includes two copies of a five residue motif is found in a number of bacterial proteins bearing similarity to the protein CpxP. This is a periplasmic protein that aids in combating extracytoplasmic protein-mediated toxicity, and may also be involved in the response to alkaline pH. Another member of this family, Spy, is also a periplasmic protein that may be involved in the response to stress. The homology between CpxP and Spy may indicate that these two proteins are functionally related.	8.22789e-06
NC_010551.1\|WP_006755042.1\|1840940_1842041_-\|NAD(P)H-binding-protein	gnl\|CDD\|224662	COG1748, LYS9, Saccharopine dehydrogenase and related proteins [Amino acid transport and metabolism].	3.04077e-85
NC_010551.1\|WP_012363935.1\|1840222_1840840_+\|ATP-binding-protein	gnl\|CDD\|379324	pfam13671, AAA_33, AAA domain. This family of domains contain only a P-loop motif, that is characteristic of the AAA superfamily. Many of the proteins in this family are just short fragments so there is no Walker B motif.	8.92251e-20
NC_010551.1\|WP_011656931.1\|1844532_1844895_-\|DUF3022-domain-containing-protein	gnl\|CDD\|378603	pfam11226, DUF3022, Protein of unknown function (DUF3022). This family of proteins with unknown function appears to be restricted to Proteobacteria.	1.11302e-49
NC_010551.1\|WP_012363938.1\|1844907_1845696_-\|YhfC-family-intramembrane-metalloprotease	gnl\|CDD\|337619	pfam10086, DUF2324, Putative membrane peptidase family (DUF2324). This domain, found in various hypothetical bacterial proteins, has no known function. This family appears to be related to the prenyl protease 2 family pfam02517, suggesting this family may be peptidases.	3.75061e-52

>NC_010551.1|WP_006755042.1|1840940_1842041_-|NAD(P)H-binding-protein
MKIAIVGAGLIGHTIAHMLRETGDYEVVAFDRDADALAKLSREGIATQRVDSADANAIREAVKGFDALVNALPYYLAVNVAAAAKAAGVHYFDLTEDVRATHAIRELADGSDRAFMPQCGLAPGFIGIAAHELVNGFSEVRDVKMRVGALPEYPTNALKYNLTWSVDGLINEYCQPCEAIRDGRKQWVQPLEGLEHFSLDGTEYEAFNTSGGLGTLCETLSGKVETLDYKSVRYPGHRELVQFLLEDLRLSSDRDTLKSIMRRAVPSTKQDVVLVFVTVTGVKDGQLVQDVFTRKIFAKDVCGMHMSAIQITTAGAMCAVLDLFREKKLPQSGFIPQEKVSLKAFLSNRFGKLYEGGTMERVHEVA
>NC_010551.1|WP_012363935.1|1840222_1840840_+|ATP-binding-protein
MTHLVFFCGHAGTGKTTLAKRLIGPLMRVTGEAFCLLDKDTLYGRYSSAAMGALTSDPNDRDSPLYLKHLRDPEYQGLLDTARENLALGIGALVVGPLSREVRDRRILDRAWLGIGPEIALTVIWVHTAEDVAHQRIVARGNPNDAYKLAHWDEYRQRRFVPTGHECDGIVMFDNTAPSDADIDALLYRIVPPAPQATLVPPLPA
>NC_010551.1|WP_012363934.1|1840079_1840226_+|cytochrome-bd-I-oxidase-subunit-CydX
MWYFSWILGIGVALGFGIINVMWLEAEVFPREDKRTDASRAGSGSRYS
>NC_010551.1|WP_012363933.1|1838921_1839899_-|magnesium/cobalt-transporter-CorA
MLINCAAYQDGRKLADIDIDAISDYVSKPECFVWVALKDPTPDEIDLMGEEFALHELALEDARKGHQRPKIEEYGDSLFAVLHTVELDEDGEFNVGELNVFVGPNYVLSIRNHTEQDFRAVRKRCEREPHLLQEGSAFVFYALMDQVVDRYFPILETLGTELEELEDRIFAKASLASSRAIIEDLYSLKRRLVMLYQHTAPLMEPLAKLTGGRIPQVCSGMQHYFRDVYDHLQRIVKTIEGRREMVVTAIQVNLGMISLAENEVTKRLGSFAALFAIPTMIAGIYGMNFANMPELHLKYGFYGCIAVMVAADLALWWRFKRAGWL
>NC_010551.1|WP_006755038.1|1838624_1838912_+|YciI-family-protein
MHYQLIYELVDDYLSRREQYRAEHLALAKAATERGELMLAGALQDPADQAVLVFEGDSPEVAESFARADPYVQNGLVKSWRVRPWRVVVGKHAPH
>NC_010551.1|WP_006755037.1|1837692_1838181_-|YbaK/EbsC-family-protein
MPVSATLQDCLRQKSSRYEVVYHPYSHTSMETAAAAHIPGDRLAKTVLLEDDEGYVAAVLPTSHAVRLSDLWVKTGRHLVLAREMELRELFKDCDLGALPPVCMAYGMKTFLEEQLAQQPEVYFEAGDHEALIHMTQDEFLSLMETAERAHFSHKMQGMWVS
>NC_010551.1|WP_012363931.1|1835884_1836592_-|SDR-family-oxidoreductase
MSTSKVIIVTGASQGIGAETVNAFRAQGHRVVATSRSIGPSDDPDLVTVAGDIGDPAVARRVVDTAIERFGRVDTLVNNAGVFIAKPFTQYTADDYAAITRVNLDGFFHVTQRAIAAMQRHGGGHVVSITTSLVDHANSNVPSALASLTKGGLNAATKSLAIEYAKAGIRVNAVSPGIINSPMHAPDTHATLASLHPVGRMGEMSDIVGAILYLDSALFVTGEILHVDGGQSAGH
>NC_010551.1|WP_012363930.1|1834872_1835805_+|LysR-family-transcriptional-regulator
MQRKFDDLLLGSIELFCLAAELGSFTLAATAASVTPAAVSRSVARLEERLGVRLFVRTTRQIRLTDSGRRYFEQCRDALSQLVDAEREATGQQATPAGVLRISMPTPYGHYRVLPLLPAFRERYPDVRVETHLSNRNIDFAEEGFDLAIRGRAPADSSLVARKLEDAELVVVATPGYLKRAGVPRAVDDLHAHECIQFELPSSGRPIPWLFNDGTAEIEIATTGGYGTSGDVLAGVTLARSGAGLFQTYRFIVELDLREGTLAEVLSGQGGRSRPFMLLYPHARYLSSRVRVFVDFLVEHLEQAPDRRKR
>NC_010551.1|WP_012363929.1|1834143_1834608_-|RidA-family-protein
MTIEQKLAALGFTLPEPPQPLGSYTAVSEAGNLLFVSGQLPLTDGKVAYTGRVGEQLSVDDGRHAAQLAALNVLAQIGKHLGGFDRLHHIVRVEGHVASADGFYGQPAVIDGASDLFAAVLGDKAGHARSAFSQRQLPADAAVILVVIAEIRPA
>NC_010551.1|WP_012363928.1|1833450_1833870_-|organic-hydroperoxide-resistance-protein
MSKIEKVLYTGKTHTTSGGRDGAARSSDGRLDIQLSSPGSAGTGTNPEQLFAAGWSACFIGAMQLAARAAKVTLPADLAVDTEVDLGMGGDAYFLQARLNVSVPGLDRDVVQHIVDTAHQTCPYSKATRGNIDVEIRIV
>NC_010551.1|WP_006755043.1|1842556_1843021_-|Lrp/AsnC-family-transcriptional-regulator
MRPPRLDQLDDLDRQLVALLQADARASVADLARQLDVARTTVVARIARLERTNVIAGYSVRLGQDVLDASIYAYVGIILTPKFGKDVLRRLDRMPEVQLLCAVSGEYDYVAWLRADSPERLNDLLDQIGTLEGVERTTTSIILSRKIDRGTIGG
>NC_010551.1|WP_012363936.1|1843387_1843924_+|Spy/CpxP-family-protein-refolding-chaperone
MKKISLTLAMLAVAAGAFAQTPPQPQTPASAAAASAPSAEQRAARHEARIEQRIKYLHDQLKITSAQESQWKTFADTMRENGETMGHLYRARMENHNVSAVDDMKQYAELAQANADGAKKLADAFAPLYQSFPAEQKALADTTFRSWLHHGGERRGSGKAKKEGKAAAAPAASAPAQP
>NC_010551.1|WP_012363937.1|1844052_1844484_+|hypothetical-protein
MLELKHIDLRTDPQARHVVKDETVTVAFADADGELMSLEGPNRYVAGDALITGSTGDRWVVSRARFDAKYLPADPALAHGTPGAYRNRPAVVLARRMDEPFTIARSENGDTLRGVAGDWVMQYAPGDYGVVQAQRFAQVYRDA
>NC_010551.1|WP_011656931.1|1844532_1844895_-|DUF3022-domain-containing-protein
MDDYLIECQSSEFDALARVICDLFPEQTRFAESSDERGRFLSVHWLAMRFGSTPKRMTLDIRIVPPALARYLALKPMQRARSHAVLHAYTEAMLGSLEERHAAGEAVERDAELELDEDFA
>NC_010551.1|WP_012363938.1|1844907_1845696_-|YhfC-family-intramembrane-metalloprotease
MTVAPVTLAVLIAATLIIALLPFVLFRILRKPLALDRRDTIVGVAVFTLFAMIVERAFHGFVLSQTPAGGWLTQPLAFVAYSALATAVFEEVGRYLGMRILNRRYGASAGDGRGIGYGIGHAGAEAWFVGVLVWGQWSYLAWLASRGQLETQLADLPGDTVVRLHVMLATLSAQSILLLLLERCAAVVVQLALSVLVWRGVRAGRAGVLPLAIVLHALAVAPALLYQVRVLPAGSLEAVYVVLAAILIAVLVKAGRSPRAAA
>NC_010551.1|WP_012363939.1|1845750_1846794_-|LacI-family-DNA-binding-transcriptional-regulator
MSDSQPSTQRPATISDVAREAGTGKTSVSRYLNGETHVLSADLRQRIETAIARLNYRPNQMARGLKRGRNRLLGMLAADLTNPYTIEVLQGVEAACHALGYMPLICHAANEVEMERRFLQLLTTYRVEGLIVNALGAEEDVLRPLRGAGIPAVLVDRTVEGFEADLIGLDNTDAIEMALAHLVARGFDAIHFVVQPFERVSSRRLREAAFRAALGARGLPVPPTVVLDLNEPAAAAAALADLDARLDDATRRGVRAALFAANAPVALAIARHLRARFGAAWQEKAALLSIDDPEWAELIGITTIRQPTYEIGYKAVEFVHERIDGAAGDVRVAMLPGELIARASTAS
>NC_010551.1|WP_012363940.1|1847116_1848082_-|bifunctional-glyoxylate/hydroxypyruvate-reductase-B
MKPRIVAYKPLPDDVLAYLREHADVVQADGPAALADALGDAHGAIGASLKVTPQMLDRAPKLKAWSTISVGYDNFDVADLTRRGIVLAHTPDVLTESTADTVFSLILASARRVVELAEWVKAGRWHRSIGPDLYGTDVQGKTLGIVGLGRIGGAVARRAALGFRMQVLYTNRSAHAEAETQYGARRVTLDELLAQSDFVCLQVPLSPETHHLIGAAEFTKMKRGAILINASRGPVVDEAALIDALRAGTIRGAGLDVFEKEPLPADSPLLRMNNVVALPHIGSATHETRHAMARCAAENLVGALAGTLRTNLVNPDALARA
>NC_010551.1|WP_012363941.1|1848087_1849368_-|MFS-transporter
MAANLAVRRWWTIMPIVFITYSLAYLDRANYGFAAAAGINQDLGISKGLSSLIGALFFLGYFFFQIPGAIYAERRSVKKLVFVSLVLWGACAALTGVVADIPSLMVIRFVLGVVEAAVMPAMLIYISNWFTKSERSRANTFLILGNPVTVLWMSIVSGYLVHEFGWRHMFIAEGVPAVIWAVCWWFLVQDKPADSPWLTTQEKRDLDAALAAEQAAIKPVRNYGEAFRSPAVIKLCAQYFCWSIGVYGFVLWLPSIVKNGSELGMVATGWLSALPYLAATIAMLVASWASDKVGSRRGFVWPFLLIGAAAFAASYALGSSHFWISYALLVVAGAAMYAPYGPFFAIVPELLPKNVAGGAMALINSMGALGSFVGSYFVGYLNGATGSPVASYAFMSAALVAAVILTLSVKPQARDAHPLATPLQGK
>NC_010551.1|WP_006754794.1|1849528_1850521_-|sugar-kinase
MKAALDVVTYGEAMAMFVAAEPCHLAHAAQFTKRIAGADLNVAIGLSRLGFRVGWMSRVGRDSFGTYVLDTLAREGIDASCVTVDPRYPTGFQLKSRNDDGSDPTVEYFRKGSAASHLSCDDYVADYVLGARHLHLTGVAPAISATSCELAFQLAREMRAAGKTISFDPNLRPTLWPSADVMAKTLNALATLADWVLPGLAEGRQLTGHDTPADIAGFYLARGARGVVIKLGPEGAYFRTADGRAGTVAGERVAKVVDTVGAGDGFAVGVVSALLEGRSVEQAVARGNRIGALAIQVIGDSEGLPTRAALDQLENVSNRADRLEETVTAQ
>NC_010551.1|WP_012363942.1|1850549_1851314_-|TIM-barrel-protein
MADIVIVASAFGMDRVRQEGHRAFLATAAASGATGFEVRRELFASDDDATPAALAELGTALSAHGLWSVYSTPATLYTEAGALDADALRDTLVEADALGARFVKFQLGGFAGDAHAAQIVALSRGARARVVVENGQLPIGGALAQFRGLFDALTDAGTPDALGMTFDIGNWQWPGEAPLACAHALAPHVEYIHCKAVAGDGARRFAMAPAPGDPLVTGVLAALPQAVPRGIEFPFDAADLAGDAGRRVAWLAAA

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Crispr_ID: NC_010551_3

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_010551_3

2391838-2391909

Orphan

Consensus_repeat	Method
CCCATGCAAAGCTGTCGACCGGA	CRISPRCasFinder

1 spacers

The CRISPR arrays of NC_010551_3

>merge|NC_010551|3|2391838-2391909|CRISPRCasFinder
CCCATGCAAAGCTGTCGACCGGAGTTGGCGCTTGAGCACTTACTCCGGGCCCATGCAAAGCTGTCGACCGGA

>NC_010551|3|3|2391838-2391909|CRISPRCasFinder
CCCATGCAAAGCTGTCGACCGGA	GTTGGCGCTTGAGCACTTACTCCGGG
CCCATGCAAAGCTGTCGACCGGA

Protein	Signature genes	Signature genes Name	Protein_function
NC_010551.1\|WP_012364301.1\|2389096_2389771_+\|membrane-protein	unknown	unknown	gnl\|CDD\|225775
NC_010551.1\|WP_012364308.1\|2396396_2397089_+\|thiol:disulfide-oxidoreductase	unknown	unknown	gnl\|CDD\|183298
NC_010551.1\|WP_012364297.1\|2379461_2379797_-\|hypothetical-protein	unknown	unknown	unknown
NC_010551.1\|WP_012364302.1\|2389907_2390555_+\|hypothetical-protein	unknown	unknown	unknown
NC_010551.1\|WP_012364299.1\|2386757_2387975_+\|DUF2863-family-protein	unknown	unknown	gnl\|CDD\|371362
NC_010551.1\|WP_012364296.1\|2378601_2379447_+\|23S-rRNA-(adenine(2030)-N(6))-methyltransferase-RlmJ	unknown	unknown	gnl\|CDD\|225509
NC_010551.1\|WP_012364298.1\|2380306_2380711_-\|Cu(I)-responsive-transcriptional-regulator	unknown	unknown	gnl\|CDD\|133383
NC_010551.1\|WP_012364294.1\|2376565_2377354_-\|3-hydroxybutyrate-dehydrogenase	unknown	unknown	gnl\|CDD\|184025
NC_010551.1\|WP_012364312.1\|2399259_2400456_-\|acyl-CoA-dehydrogenase	unknown	unknown	gnl\|CDD\|132248
NC_010551.1\|WP_012364309.1\|2397139_2397616_-\|MaoC-family-dehydratase	unknown	unknown	gnl\|CDD\|239534
NC_010551.1\|WP_012364303.1\|2390633_2391788_-\|carboxypeptidase-family-protein	unknown	unknown	gnl\|CDD\|349453
NC_010551.1\|WP_012364307.1\|2395432_2396224_+\|enoyl-CoA-hydratase	unknown	unknown	gnl\|CDD\|181009
NC_010551.1\|WP_012364305.1\|2393343_2394516_+\|pyridoxal-phosphate-dependent-aminotransferase	unknown	unknown	gnl\|CDD\|181642
NC_010551.1\|WP_011657467.1\|2392814_2393312_+\|putative-toxin-antitoxin-system-toxin-component,-PIN-family	unknown	unknown	gnl\|CDD\|379205
NC_010551.1\|WP_012364306.1\|2394564_2395221_-\|glutathione-S-transferase	unknown	unknown	gnl\|CDD\|198344
NC_010551.1\|WP_012364310.1\|2397612_2398074_-\|MaoC-family-dehydratase	unknown	unknown	gnl\|CDD\|239538
NC_010551.1\|WP_012364300.1\|2388190_2389021_+\|response-regulator-transcription-factor	unknown	unknown	gnl\|CDD\|225107
NC_010551.1\|WP_012364304.1\|2391974_2392757_-\|peroxide-stress-protein-YaaA	unknown	unknown	gnl\|CDD\|234999
NC_010551.1\|WP_012364295.1\|2377518_2378490_+\|NADP-dependent-aryl-alcohol-dehydrogenase	unknown	unknown	gnl\|CDD\|381369
NC_010551.1\|WP_012364311.1\|2398106_2399240_-\|acyl-CoA-dehydrogenase	unknown	unknown	gnl\|CDD\|132247

Protein	Function_ID	Function_description	E-value
NC_010551.1\|WP_012364301.1\|2389096_2389771_+\|membrane-protein	gnl\|CDD\|225775	COG3235, COG3235, Predicted membrane protein [Function unknown].	2.42257e-17
NC_010551.1\|WP_012364296.1\|2378601_2379447_+\|23S-rRNA-(adenine(2030)-N(6))-methyltransferase-RlmJ	gnl\|CDD\|225509	COG2961, ComJ, Protein involved in catabolism of external DNA [General function prediction only].	2.1053e-127
NC_010551.1\|WP_011657467.1\|2392814_2393312_+\|putative-toxin-antitoxin-system-toxin-component,-PIN-family	gnl\|CDD\|379205	pfam13470, PIN_3, PIN domain. Members of this family of bacterial domains are predicted to be RNases (from similarities to 5'-exonucleases).	1.87827e-26
NC_010551.1\|WP_012364299.1\|2386757_2387975_+\|DUF2863-family-protein	gnl\|CDD\|371362	pfam11062, DUF2863, Protein of unknown function (DUF2863). This bacterial family of proteins have no known function.	0
NC_010551.1\|WP_012364305.1\|2393343_2394516_+\|pyridoxal-phosphate-dependent-aminotransferase	gnl\|CDD\|181642	PRK09082, PRK09082, methionine aminotransferase; Validated.	0
NC_010551.1\|WP_012364298.1\|2380306_2380711_-\|Cu(I)-responsive-transcriptional-regulator	gnl\|CDD\|133383	cd01108, HTH_CueR, Helix-Turn-Helix DNA binding domain of CueR-like transcription regulators. Helix-turn-helix (HTH) transcription regulators CueR and ActP, copper efflux regulators. In Bacillus subtilis, copper induced CueR regulates the copZA operon, preventing copper toxicity. In Rhizobium leguminosarum, ActP controls copper homeostasis; it detects cytoplasmic copper stress and activates transcription in response to increasing copper concentrations. These proteins are comprised of two distinct domains that harbor the regulatory (effector-binding) site and the active (DNA-binding) site. Their conserved N-terminal domains contain winged HTH motifs that mediate DNA binding, while the C-terminal domains have two conserved cysteines that define a monovalent copper ion binding site. These proteins share the N-terminal DNA binding domain with other transcription regulators of the MerR superfamily that promote transcription by reconfiguring the spacer between the -35 and -10 promoter elements.	1.33634e-69
NC_010551.1\|WP_012364294.1\|2376565_2377354_-\|3-hydroxybutyrate-dehydrogenase	gnl\|CDD\|184025	PRK13394, PRK13394, 3-hydroxybutyrate dehydrogenase; Provisional.	2.54718e-159
NC_010551.1\|WP_012364312.1\|2399259_2400456_-\|acyl-CoA-dehydrogenase	gnl\|CDD\|132248	TIGR03204, pimC_large, pimeloyl-CoA dehydrogenase, large subunit. Members of this protein family are the PimC proteins of species such as Rhodopseudomonas palustris and Bradyrhizobium japonicum. The pimFABCDE operon encodes proteins for the metabolism of straight chain dicarboxylates of seven to fourteen carbons. Especially relevant is pimeloyl-CoA, basis of the gene symbol, as it is a catabolite of benzoyl-CoA degradation, which occurs in Rhodopseudomonas palustris.	1.73323e-175
NC_010551.1\|WP_012364308.1\|2396396_2397089_+\|thiol:disulfide-oxidoreductase	gnl\|CDD\|183298	PRK11752, PRK11752, putative S-transferase; Provisional.	3.06731e-84
NC_010551.1\|WP_012364303.1\|2390633_2391788_-\|carboxypeptidase-family-protein	gnl\|CDD\|349453	cd06234, M14_PaCCP-like, Peptidase M14-like domain of ATP/GTP binding proteins and cytosolic carboxypeptidases similar to Pseudomonas aerugnosa CCP (PaCCP). A bacterial subgroup of the Peptidase M14-like domain of Nna-1 (Nervous system Nuclear protein induced by Axotomy), also known as ATP/GTP binding protein (AGTPBP-1) and cytosolic carboxypeptidase (CCP)-like proteins. This subgroup includes PaCCP from Pseudomonas aeruginosa, a carboxypeptidase homologous to M14D subfamily of human CCPs. Structural complexes with well-known inhibitors of metallocarboxypeptidases indicate that PaCCP might only possess C-terminal hydrolase activity against cellular substrates of particular specificity. The Peptidase M14 family of metallocarboxypeptidases are zinc-binding carboxypeptidases (CPs) which hydrolyze single, C-terminal amino acids from polypeptide chains, and have a recognition site for the free C-terminal carboxyl group, which is a key determinant of specificity. Nna1-like proteins are active metallopeptidases that are thought to act on cytosolic proteins (such as alpha-tubulin in eukaryotes) to remove a C-terminal tyrosine. Nna1-like proteins from the different phyla are highly diverse, but they all contain a unique N-terminal conserved domain right before the CP domain. It has been suggested that this N-terminal domain might act as a folding domain.	7.72586e-152
NC_010551.1\|WP_012364309.1\|2397139_2397616_-\|MaoC-family-dehydratase	gnl\|CDD\|239534	cd03450, NodN, NodN (nodulation factor N) contains a single hot dog fold similar to those of the peroxisomal Hydratase-Dehydrogenase-Epimerase (HDE) protein, and the fatty acid synthase beta subunit. Rhizobium and related species form nodules on the roots of their legume hosts, a symbiotic process that requires production of Nod factors, which are signal molecules involved in root hair deformation and meristematic cell division. The nodulation gene products, including NodN, are involved in producing the Nod factors, however the role played by NodN is unclear.	1.94742e-71
NC_010551.1\|WP_012364307.1\|2395432_2396224_+\|enoyl-CoA-hydratase	gnl\|CDD\|181009	PRK07511, PRK07511, enoyl-CoA hydratase; Provisional.	3.7365e-155
NC_010551.1\|WP_012364306.1\|2394564_2395221_-\|glutathione-S-transferase	gnl\|CDD\|198344	cd10424, GST_C_9, C-terminal, alpha helical domain of an unknown subfamily 9 of Glutathione S-transferases. Glutathione S-transferase (GST) C-terminal domain family, unknown subfamily 9; composed of uncharacterized proteins with similarity to GSTs. GSTs are cytosolic dimeric proteins involved in cellular detoxification by catalyzing the conjugation of glutathione (GSH) with a wide range of endogenous and xenobiotic alkylating agents, including carcinogens, therapeutic drugs, environmental toxins, and products of oxidative stress. GSTs also show GSH peroxidase activity and are involved in the synthesis of prostaglandins and leukotrienes. The GST fold contains an N-terminal thioredoxin-fold domain and a C-terminal alpha helical domain, with an active site located in a cleft between the two domains. GSH binds to the N-terminal domain while the hydrophobic substrate occupies a pocket in the C-terminal domain.	1.26008e-39
NC_010551.1\|WP_012364310.1\|2397612_2398074_-\|MaoC-family-dehydratase	gnl\|CDD\|239538	cd03454, YdeM, YdeM is a Bacillus subtilis protein that belongs to a family of prokaryotic proteins of unkown function. YdeM has sequence similarity to the hot-dog fold of (R)-specific enoyl-CoA hydratase. Other enzymes with this fold include the peroxisomal Hydratase-Dehydrogenase-Epimerase (HDE) protein, and the fatty acid synthase beta subunit.	3.13463e-68
NC_010551.1\|WP_012364300.1\|2388190_2389021_+\|response-regulator-transcription-factor	gnl\|CDD\|225107	COG2197, CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription].	3.63275e-34
NC_010551.1\|WP_012364304.1\|2391974_2392757_-\|peroxide-stress-protein-YaaA	gnl\|CDD\|234999	PRK02101, PRK02101, peroxide stress protein YaaA.	9.60735e-143
NC_010551.1\|WP_012364295.1\|2377518_2378490_+\|NADP-dependent-aryl-alcohol-dehydrogenase	gnl\|CDD\|381369	cd19143, AKR_AKR6C1_2, AKR6C family of aldo-keto reductase (AKR). Voltage-gated potassium channel subunit beta (KCAB) from Arabidopsis thaliana and Egeria densa are founding members of aldo-keto reductase family 6 member C1 (AKR6C1) and C2 (AKR6C2), respectively. KCAB, also called Shaker channel b-subunit, or K(+) channel subunit beta, or potassium voltage beta 1, or KV-beta1, or KAB1, is a probable accessory potassium channel protein which modulates the activity of the pore-forming alpha subunit.	0
NC_010551.1\|WP_012364311.1\|2398106_2399240_-\|acyl-CoA-dehydrogenase	gnl\|CDD\|132247	TIGR03203, pimD_small, pimeloyl-CoA dehydrogenase, small subunit. Members of this protein family are the PimD proteins of species such as Rhodopseudomonas palustris, Bradyrhizobium japonicum. The pimFABCDE operon encodes proteins for the metabolism of straight chain dicarboxylates of seven to fourteen carbons. Especially relevant is pimeloyl-CoA, basis of the gene symbol, as it is a catabolite of benzoyl-CoA degradation, which occurs in Rhodopseudomonas palustris.	7.39068e-93

>NC_010551.1|WP_012364303.1|2390633_2391788_-|carboxypeptidase-family-protein
MTLSITSNFDAGAIDVVSCDSPDAIRLRVRGDNRSEFAQWFYYRLTGARGERCVMSFENAAECAYPSGWRNYSAVASYDRVDWFRVPTTFDGKTMTIDHTPEFDSIYYAYFEPYSEERHAAFLGAVQQLPQARVVELGRTVEGRPMSLLTLGTPEVDGAPKKKVWVIARQHPGETMAEWFIEGLVKRLAGWGDWAGDPVARKLYDRATFYIVPNMNPDGSVHGNLRTNAAGANLNREWMEPDAERSPEVLAVRDAIHAIGCDMFFDIHGDEDLPYVFVAGSEMLPSFTEQQRKEQTAFIDAFKVASPDFQTEHGYAASKYKEDALKLASKYIGHQFGCLSLTLEMPFKDNANLPDERVGWNGERSAALGAAMLAAILVHVETFA
>NC_010551.1|WP_012364302.1|2389907_2390555_+|hypothetical-protein
MPHSLLTNNQMDSSPASLRIFRALGKLAACVAGLSLALPAPVLADLLDQRSELINKFVNEMHADPIVADCAAHGSFIASTSSAFDRVDFAPKAFENGNAAITPWNDSFDQGKQRVKVDNIVTVDGLGIHSDGSDPTPLKFRCGYVGQQMLAFSWNDPVPPLKPRVERPSSSTKKFTGKSHRGKVKATSRTGKKAAATKKSSGQKKVVKKKTAKKS
>NC_010551.1|WP_012364301.1|2389096_2389771_+|membrane-protein
MGFLFTPLPLWVGIGGWIGAVALLALALWNRPFVRLQDATLQHVWLALVTAITVLWASNAWLEDGTVMHLLGATLLVTLFDWTLALIAMGAVTGIAAIVFDAPWHGIGLTYLIYGALPVAVSALLQRAVIAWLPHNLTSFITGQGFLSPAIAIVAVAAAAAGVQLALADGVPVVIPAGYLLNTALLALGEAWFTGMATALIAVYRPAWVTTFDVRRYRLGGPRA
>NC_010551.1|WP_012364300.1|2388190_2389021_+|response-regulator-transcription-factor
MRFLVLNSDAERRDGLKALLRQIDRHASINDAPDGFQARRLLRAQRFDLVAINWPDVGRLSELQALCSACSPTPAAVLIDESTPEAIQRFYNYGVAGVIPHSMRPHLIVRALEMVLLGGHYIPPIALSLLPSAAAARHDAHFQTLAGSLPRRPASRLLSPRQAQIMRFVHMGNTNKMIARTLGISEGTVKIHLASIFQQLGAANRAAAVAIYNGWLSPHLEVLLANRERAQKPTIGERGPVPLRMQRKNRPYPLPDANTADLPLAAEPPARFRRER
>NC_010551.1|WP_012364299.1|2386757_2387975_+|DUF2863-family-protein
MRQRIAKRLPPDADKLVGLSLALFASGSRIEDRFWEAKLDALLAKIVRNGNQTTLDAALDHLQQNHPDAYGALADMAETHSESMVIEHDGQPYDALLVAVPVLAWTRYMIPSGPLKGDVADALRTQLQAHVLASGTLVGLAPFLYSIDQLPRHHVETYRLAQQLAHAAIGQHAAKLSFGDLPETSPILADPRFLLAVVAAPAGAPLFRWQEEEHGNRIERGQCLEQWTAQGGPSLSVALPGCEFECLLPDAYYSACRDADERIRPHTVRTAIRYLFDTLGAAPQELRAVVAGFGERRIDEYRVGFTRRASNDVIYGVVWPLYGRENGDVSIDNATLEGEAPMEGPMEEIVSLLKECGVTDVRRHAGRFEPEYCDDCGVPLYADPLGEIVHAEMPEDASPAQPHFH
>NC_010551.1|WP_012364298.1|2380306_2380711_-|Cu(I)-responsive-transcriptional-regulator
MNIGDASRESGVSAKMIRYYEQVGLLAPSKRSEAGYRIYGSDEIHILRFIRQARRLGFLVEDIRKLLMLWQDRSRASAEVKSIALEHVAELDKRIAELSDMRNTLADLAAHCHGDGRPECPILARLADPVGEPD
>NC_010551.1|WP_012364297.1|2379461_2379797_-|hypothetical-protein
MRLRLDVRHASRARLVLGAAVLVHGIAAGAATSSKPLILDTQRGIQDGQGGLVLQTAPLSSEPIVEPAGMRMPAGQGPNSSVPLFVAPYINVPGWGASRANQPRPAPRLQP
>NC_010551.1|WP_012364296.1|2378601_2379447_+|23S-rRNA-(adenine(2030)-N(6))-methyltransferase-RlmJ
MLSYRHGFHAGNHADVLKHAVVVQLLRYLNKKDKSYWYIDTHAGAGVYSLREGYAAKTGEFDTGIGLLWNDKNLPEALGDYIDEVRALNDDGELHYYPGSPYLAWRAMREQDRMRLFEMHTTEIDVLRHNFRDAGRRAMIYAGDGFEGIKALLPPPPRRALVLIDPSYEDKKDYARTVTCVTECLKRFATGCYAIWYPQVARVESQRFPEQLKRLQPNNWVHLTLTVSNPPADGLGLYGSGMFILNPPYTLAQSMNEALPYLVERLGQDSGARCEIEHRGN
>NC_010551.1|WP_012364295.1|2377518_2378490_+|NADP-dependent-aryl-alcohol-dehydrogenase
MHYRRLGRSGLQISELSLGSWVTYGNQVDQRAARECLAAARDAGVNFFDNAEVYAGGKSEEIMGQALKSLGWPRISYLVSTKFFWGLAEAPNQYHTLNRKYLLNAIDGSLRRLQLDYVDLVYCHRPDPNTPIEETVWAMSDMIVRGKALYWGTSEWSADEIRAAYEIAERHHLHKPVVEQPQYNLFHRTRVEREYARLYDDYGLGLTTWSPLASGLLTGKYRNGVPPGSRAELQGYDWLRDRLTDPTSNDVVERLGGIAAELGCSTAQLAIAWVLANPRVSSVITGASRIEQIGDNMRALDVAAKLTPEVRQRIEEAVGDAYE
>NC_010551.1|WP_012364294.1|2376565_2377354_-|3-hydroxybutyrate-dehydrogenase
MAADLSGKTAVVTGAASGIGKEIALELAKAGAAVAIADLNQDGANAVADEINKAGGKAIGVAMDVTNEDAVNNGIDKVAEAFGSVDILVSNAGIQIVNPIENYSFSDWKKMQAIHVDGAFLTTKAALKHMYKDDRGGVVIYMGSVHSHEASPLKSAYVTAKHGLLGLARVLAKEGAKHNVRSHVVCPGFVRTPLVDKQIPEQAKELGISEEEVIKKVMLGNTVDGVFTTVQDVAQTVLFLSAFPSAALTGQSVVVSHGWFMK
>NC_010551.1|WP_012364304.1|2391974_2392757_-|peroxide-stress-protein-YaaA
MIIVLSPAKSLDYDTPAHVPSYTKPAFVDDASELIDGLRKLSPQDIATLMDISDPLARLNFQRYADWSPTFSPANAKQAVLAFNGDVYEGFDAKSLSAADLDYAQQHVRVLSGLYGLLRPLDLLQPYRLEMGTRFANARGKDLYAFWGDRITRALNEQLETRSGAARVLVNCASTEYFKSVKPKLLAAPVVTPVFEDWKGGRYKIISFHAKRARGLMARYIVENRIAEPAALKDFAMEDYVFDAAASNDSTYVYRRRIGE
>NC_010551.1|WP_011657467.1|2392814_2393312_+|putative-toxin-antitoxin-system-toxin-component,-PIN-family
MTRSSAPHAAHRVVLDSNVWIDILVFDDPATRPIRAALERGTLAAVIDGRCLNELELVLDYPQFRERAIDKAEALATVARLTSRVEPPPVDADAPPLPKCKDRDDQKFLELARAAQADWLVSKDRALLKLAKRTARDFGFRIAQPAPFTEACALDAASAIPTTPA
>NC_010551.1|WP_012364305.1|2393343_2394516_+|pyridoxal-phosphate-dependent-aminotransferase
MNAPSDMPTNPVFPSRLPNVGTTIFTVMSALAAEKGAVNLGQGFPDFDCDPRIVDAVAAAMRDGHNQYPPMAGVAPLRDAIADKIAQVYGRRYDPATEITVTAGATQALLTAILCAVHPGDEVIVVEPTYDSYLPSIELAGGKPVFVTLEAPDYAIPFDRLAAAITPKTRMIMINTPHNPTGTVWREADMRKLEEIVRGTNVLILSDEVYEHMVYDGARHESVARYPELAERSFIVSSFGKTYHVTGWKIGYVAAPAALMAEFRKVHQFNVFTVNTPTQIGLADYLRDPAPYLTLPDFYQKKRDFFRAGLERTRFKLLPCTGTYFQCVDYSAISDLPEAEFSKWLTSEIGVAAIPVSAFYHAPHESGVVRFCFAKQESTLASALERLARL
>NC_010551.1|WP_012364306.1|2394564_2395221_-|glutathione-S-transferase
MLQLCGIPLSNYYNKVKFVLLEHDIPFEEATCTLPVSDPALLADSPLGKIPFLKTEEGALFESQVIIEYLAARYPDKAIFPAGPFAAAKVRELVETLELYLEWTAREVYTEAFFGGKVSDGTKAHVEKRLPRAIDAFKRMTQFSPYVLGDTFGLADIAASVHLPVIGMATKAIFGRDFLLDAGIDWKAHAKLVGERPAAQRVAADRKAYVEATAAARQ
>NC_010551.1|WP_012364307.1|2395432_2396224_+|enoyl-CoA-hydratase
MSAELLASRPPESESTLVLTLSNPGARNALHPDMYAAGVEALATAERDPAIRAVVLTGADRFFCAGGNLNRLLENRAKDPSYQADSIDQLGAWITAIRASTKPVIAAVEGAAAGAGFSLALACDLIVAAHDAKFVMSYARVGLTPDGGGSWFLARALPRALAAEILFEGKPVAAERLHALGVVNRLAVPGAALSDALAWADSLAGISPNALTRIKSLLDDAPAQPLETHLGTERDHFVASLHHADAFEGITAFLEKRQPRYKR
>NC_010551.1|WP_012364308.1|2396396_2397089_+|thiol:disulfide-oxidoreductase
MIDVYSWATPNGHKVHIMLEETGLAYRVHPVDIGAGDQFKPEFLKISPNNKIPAIVDADGPGGKPISLFESGAILVYLAEKTGKFLPTDPAGRYATLEWLMFQMGGVGPMLGQAHHFRLYAPEQIEYAVNRYTNEAKRLYNVMEKRLGESEYLAGDTYTIADIATFPWTRSWQNQGIVLDELPNVKRWQEAIAARPAVQRGVEVLASMRKALQDDKAREMLFGATQYAKH
>NC_010551.1|WP_012364309.1|2397139_2397616_-|MaoC-family-dehydratase
MTDVTLPLIASPQALHAQVGAEPLASGWVEIDQRRVDGFADATGDRQWIHVDPERARRESPFGGPIAHGFLTLSLIPALMADAMRFEQKMGVNYGLNRVRFLKPVPVGTRVRALFAVKETAEAARGGVQVTWSVSMQAERRDTPLLVCAAEFITLHYF
>NC_010551.1|WP_012364310.1|2397612_2398074_-|MaoC-family-dehydratase
MGISYEDLEVGSTTEIGRYTFEPDDIKTFAQRYDPQPFHLDEEAGKASPFGGLVASGWHTCSVFMSLLIKKLGPDSTSMGSPGIDSIRWLKPVRAGDTITMLQKIHDKRVSASKPDRGIVSTEWIGINGAGDTVISVHTKVIFGLRHPQGAGA
>NC_010551.1|WP_012364311.1|2398106_2399240_-|acyl-CoA-dehydrogenase
MDFSFTDEQQQFADALRRYLGEQYGFDARQAIVRSDAGVSDAQWSAFAELGLTALPVPEAQGGFGGGPVDMLVAMQELGRALVVEPYWATAVGIEALRLAGSGTGDDAALLEAVALGQKRLAVAFHEPRARYDLYELGTQAREQGGACRLTGTKSVVQHGAQAHAWIVPARVDGGGIGLFVVERDAAGVKLVDYRTIDGQRAATIELHETPARQLTGGARDAAALEQIADYATFLLCAEAVGALDELNRATVEYTKTREQFGVPIARFQALQHRMVDMLIHAEQARSLTYLAAVRYAGGDADARRKAVSAAKARVGAAARFVGQQAVQLHGGMGVTNEVAAAHLFKRLSIIETTLGDTDHHLARITALPDFAQADAA
>NC_010551.1|WP_012364312.1|2399259_2400456_-|acyl-CoA-dehydrogenase
MDLDYSPADDAFRVDVRAWLEANLPHALRAKVLDHKRLDREDFASWHRILGQRGWSAPAWPAEYGGPGWNATQRHIWDEECARIGAPTVLPFGVSMVAPVLMKYGSEAQKRHYLPRILDGTDWWCQGYSEPGSGSDLASLRTRAERHGDHYVVNGQKTWTTLGQYADMMFCLVRTDPAAKKQEGISFLLIDMATPGITVRPIITLDEDHEVNEVFFEDVKVPVENLVGDENRGWTYAKYLLGHERTGIARVGASKRELVFLKRVASHQQKNGKPLLADPVFAAKVAALEVELMALEVTVLRVVSRETSGKGPGPEASMLKIKGTEVQQALTELMFEAIGPLAAPFDVPFLEGKREHSIAGDDDAAPLAAYYFNYRKTSIYGGSNEIQKNIIAQMILGL

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Crispr_ID: NC_010551_4

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_010551_4

2483005-2483114

Orphan

Consensus_repeat	Method
GCCGTTTCTGGCGACGCGGTAACGGCG	CRISPRCasFinder

1 spacers

The CRISPR arrays of NC_010551_4

>merge|NC_010551|4|2483005-2483114|CRISPRCasFinder
GCCGTTTCTGGCGACGCGGTAACGGCGGGTGGCGGGCGGCGAGCATGGGCGGCACGTTCCAGCGGCGGGTGGTAGCCGGCGCGGCCGTTTCTGGCGACGCGGCAACGGCG

>NC_010551|4|4|2483005-2483114|CRISPRCasFinder
GCCGTTTCTGGCGACGCGGTAACGGCG	GGTGGCGGGCGGCGAGCATGGGCGGCACGTTCCAGCGGCGGGTGGTAGCCGGCGCG
GCCGTTTCTGGCGACGCGGCAACGGCG

Protein	Signature genes	Signature genes Name	Protein_function
NC_010551.1\|WP_012364354.1\|2475294_2475861_+\|FUSC-family-protein	unknown	unknown	gnl\|CDD\|379231
NC_010551.1\|WP_006752228.1\|2475914_2476295_-\|RcnB-family-protein	unknown	unknown	gnl\|CDD\|227742
NC_010551.1\|WP_041489839.1\|2484628_2488162_-\|DNA-polymerase-III-subunit-alpha	unknown	unknown	gnl\|CDD\|235554
NC_010551.1\|WP_012364368.1\|2495056_2499889_+\|DNA-translocase-FtsK	unknown	unknown	gnl\|CDD\|224588
NC_010551.1\|WP_012364363.1\|2490224_2491760_-\|DEAD/DEAH-box-helicase	unknown	unknown	gnl\|CDD\|236722
NC_010551.1\|WP_012364365.1\|2492687_2492882_-\|hypothetical-protein	unknown	unknown	unknown
NC_010551.1\|WP_012364353.1\|2474009_2475269_+\|MFS-transporter	unknown	unknown	gnl\|CDD\|340883
NC_010551.1\|WP_012364357.1\|2479263_2480106_+\|glycosyltransferase	unknown	unknown	gnl\|CDD\|133029
NC_010551.1\|WP_012364366.1\|2492900_2494115_-\|formate-dependent-phosphoribosylglycinamide-formyltransferase	unknown	unknown	gnl\|CDD\|236454
NC_010551.1\|WP_006752229.1\|2476391_2478143_-\|lipid-A-export-permease/ATP-binding-protein-MsbA	unknown	unknown	gnl\|CDD\|131258
NC_010551.1\|WP_041489837.1\|2471596_2472775_+\|collagen-like-triple-helix-repeat-containing-protein	unknown	unknown	gnl\|CDD\|374271
NC_010551.1\|WP_012364352.1\|2473044_2474013_+\|PRC-barrel-domain-containing-protein	unknown	unknown	gnl\|CDD\|237865
NC_010551.1\|WP_012364358.1\|2480242_2481523_+\|O-antigen-ligase-family-protein	unknown	unknown	gnl\|CDD\|225844
NC_010551.1\|WP_012364360.1\|2483213_2484308_-\|glycosyltransferase-family-9-protein	unknown	unknown	gnl\|CDD\|223928
NC_010551.1\|WP_012364367.1\|2494331_2494877_+\|META-domain-containing-protein	unknown	unknown	gnl\|CDD\|377111
NC_010551.1\|WP_012364364.1\|2492205_2492589_-\|lysozyme-inhibitor	unknown	unknown	gnl\|CDD\|378282
NC_010551.1\|WP_012364362.1\|2489261_2490146_+\|tRNA-glutamyl-Q(34)-synthetase-GluQRS	unknown	unknown	gnl\|CDD\|274810
NC_010551.1\|WP_011657537.1\|2488384_2489239_+\|sulfurtransferase	unknown	unknown	gnl\|CDD\|235405
NC_010551.1\|WP_041489838.1\|2481696_2482875_-\|glycosyltransferase-family-9-protein	unknown	unknown	gnl\|CDD\|223928
NC_010551.1\|WP_012364356.1\|2478366_2479119_+\|glycosyltransferase-family-2-protein	unknown	unknown	gnl\|CDD\|133005

Protein	Function_ID	Function_description	E-value
NC_010551.1\|WP_012364354.1\|2475294_2475861_+\|FUSC-family-protein	gnl\|CDD\|379231	pfam13515, FUSC_2, Fusaric acid resistance protein-like.	1.00857e-10
NC_010551.1\|WP_006752228.1\|2475914_2476295_-\|RcnB-family-protein	gnl\|CDD\|227742	COG5455, COG5455, Predicted integral membrane protein [Function unknown].	2.65127e-21
NC_010551.1\|WP_041489839.1\|2484628_2488162_-\|DNA-polymerase-III-subunit-alpha	gnl\|CDD\|235554	PRK05673, dnaE, DNA polymerase III subunit alpha; Validated.	0
NC_010551.1\|WP_012364363.1\|2490224_2491760_-\|DEAD/DEAH-box-helicase	gnl\|CDD\|236722	PRK10590, PRK10590, ATP-dependent RNA helicase RhlE; Provisional.	1.18104e-168
NC_010551.1\|WP_012364368.1\|2495056_2499889_+\|DNA-translocase-FtsK	gnl\|CDD\|224588	COG1674, FtsK, DNA segregation ATPase FtsK/SpoIIIE and related proteins [Cell division and chromosome partitioning].	9.206e-177
NC_010551.1\|WP_012364353.1\|2474009_2475269_+\|MFS-transporter	gnl\|CDD\|340883	cd17325, MFS_MdtG_SLC18_like, bacterial MdtG-like and eukaryotic solute carrier 18 (SLC18) family of the Major Facilitator Superfamily of transporters. This family is composed of eukaryotic solute carrier 18 (SLC18) family transporters and related bacterial multidrug resistance (MDR) transporters including several proteins from Escherichia coli such as multidrug resistance protein MdtG, from Bacillus subtilis such as multidrug resistance proteins 1 (Bmr1) and 2 (Bmr2), and from Staphylococcus aureus such as quinolone resistance protein NorA. The family also includes Escherichia coli arabinose efflux transporters YfcJ and YhhS. MDR transporters are drug/H+ antiporters (DHA) that mediate the efflux of a variety of drugs and toxic compounds, and confer resistance to these compounds. The SLC18 transporter family includes vesicular monoamine transporters (VAT1 and VAT2), vesicular acetylcholine transporter (VAChT), and SLC18B1, which is proposed to be a vesicular polyamine transporter (VPAT). The MdtG/SLC18 family belongs to the Major Facilitator Superfamily (MFS) of membrane transport proteins, which are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	1.15173e-26
NC_010551.1\|WP_012364357.1\|2479263_2480106_+\|glycosyltransferase	gnl\|CDD\|133029	cd04186, GT_2_like_c, Subfamily of Glycosyltransferase Family GT2 of unknown function. GT-2 includes diverse families of glycosyltransferases with a common GT-A type structural fold, which has two tightly associated beta/alpha/beta domains that tend to form a continuous central sheet of at least eight beta-strands. These are enzymes that catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. Glycosyltransferases have been classified into more than 90 distinct sequence based families.	6.77827e-20
NC_010551.1\|WP_012364366.1\|2492900_2494115_-\|formate-dependent-phosphoribosylglycinamide-formyltransferase	gnl\|CDD\|236454	PRK09288, purT, formate-dependent phosphoribosylglycinamide formyltransferase.	0
NC_010551.1\|WP_006752229.1\|2476391_2478143_-\|lipid-A-export-permease/ATP-binding-protein-MsbA	gnl\|CDD\|131258	TIGR02203, Lipid_A_export_ATP-binding/permease_protein_msbA., lipid A export permease/ATP-binding protein MsbA. This family consists of a single polypeptide chain transporter in the ATP-binding cassette (ABC) transporter family, MsbA, which exports lipid A. It may also act in multidrug resistance. Lipid A, a part of lipopolysaccharide, is found in the outer leaflet of the outer membrane of most Gram-negative bacteria. Members of this family are restricted to the Proteobacteria (although lipid A is more broadly distributed) and often are clustered with lipid A biosynthesis genes. [Cell envelope, Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides, Transport and binding proteins, Other].	0
NC_010551.1\|WP_041489837.1\|2471596_2472775_+\|collagen-like-triple-helix-repeat-containing-protein	gnl\|CDD\|374271	pfam15984, Collagen_mid, Bacterial collagen, middle region. Collagen_mid is the conserved central region of bacterial collagen triple helix repeat proteins.	5.10796e-25
NC_010551.1\|WP_012364352.1\|2473044_2474013_+\|PRC-barrel-domain-containing-protein	gnl\|CDD\|237865	PRK14951, PRK14951, DNA polymerase III subunits gamma and tau; Provisional.	0.000130821
NC_010551.1\|WP_012364358.1\|2480242_2481523_+\|O-antigen-ligase-family-protein	gnl\|CDD\|225844	COG3307, RfaL, Lipid A core - O-antigen ligase and related enzymes [Cell envelope biogenesis, outer membrane].	2.1136e-10
NC_010551.1\|WP_012364360.1\|2483213_2484308_-\|glycosyltransferase-family-9-protein	gnl\|CDD\|223928	COG0859, RfaF, ADP-heptose:LPS heptosyltransferase [Cell envelope biogenesis, outer membrane].	3.63369e-38
NC_010551.1\|WP_012364367.1\|2494331_2494877_+\|META-domain-containing-protein	gnl\|CDD\|377111	pfam03724, META, META domain. Small domain family found in proteins of of unknown function. Some are secreted and implicated in motility in bacteria. Also occurs in Leishmania spp. as an essential gene. Over-expression in L.amazonensis increases virulence. A pair of cysteine residues show correlated conservation, suggesting that they form a disulphide bond.	3.12803e-24
NC_010551.1\|WP_012364364.1\|2492205_2492589_-\|lysozyme-inhibitor	gnl\|CDD\|378282	pfam09864, MliC, Membrane-bound lysozyme-inhibitor of c-type lysozyme. Lysozymes are ancient and important components of the innate immune system of animals that hydrolyze peptidoglycan, the major bacterial cell wall polymer. Various mechanisms have evolved by which bacteria can evade this bactericidal enzyme, one being the production of lysozyme inhibitors. MliC (membrane bound lysozyme inhibitor of c-type lysozyme) of E. coli and Pseudomonas aeruginosa, possess lysozyme inhibitory activity and confer increased lysozyme tolerance upon expression in E. coli. Structural analyses show that the invariant loop of MliC plays a crucial role in the inhibition of the lysozyme by its insertion into the active site cleft of the lysozyme, where the loop forms hydrogen and ionic bonds with the catalytic residues.	1.05037e-19
NC_010551.1\|WP_012364362.1\|2489261_2490146_+\|tRNA-glutamyl-Q(34)-synthetase-GluQRS	gnl\|CDD\|274810	TIGR03838, queuosine_YadB, glutamyl-queuosine tRNA(Asp) synthetase. This protein resembles a shortened glutamyl-tRNA ligase, but its purpose is to modify tRNA(Asp) at a queuosine position in the anticodon rather than to charge a tRNA with its cognate amino acid. [Protein synthesis, tRNA and rRNA base modification].	2.46935e-159
NC_010551.1\|WP_011657537.1\|2488384_2489239_+\|sulfurtransferase	gnl\|CDD\|235405	PRK05320, PRK05320, rhodanese superfamily protein; Provisional.	0
NC_010551.1\|WP_041489838.1\|2481696_2482875_-\|glycosyltransferase-family-9-protein	gnl\|CDD\|223928	COG0859, RfaF, ADP-heptose:LPS heptosyltransferase [Cell envelope biogenesis, outer membrane].	5.91945e-57
NC_010551.1\|WP_012364356.1\|2478366_2479119_+\|glycosyltransferase-family-2-protein	gnl\|CDD\|133005	cd02511, Beta4Glucosyltransferase, UDP-glucose LOS-beta-1,4 glucosyltransferase is required for biosynthesis of lipooligosaccharide. UDP-glucose: lipooligosaccharide (LOS) beta-1-4-glucosyltransferase catalyzes the addition of the first residue, glucose, of the lacto-N-neotetrase structure to HepI of the LOS inner core. LOS is the major constituent of the outer leaflet of the outer membrane of gram-positive bacteria. It consists of a short oligosaccharide chain of variable composition (alpha chain) attached to a branched inner core which is lined in turn to lipid A. Beta 1,4 glucosyltransferase is required to attach the alpha chain to the inner core.	4.67189e-87

>NC_010551.1|WP_041489838.1|2481696_2482875_-|glycosyltransferase-family-9-protein
MSLFSSARPPRTILVAAPRRIGDVLLTTPLVRSLKARWPDAQIDMLVFRGTEGVLEHNPDVRRVIVVAQRAGFRERLRDVLSMWRRYDLACAALSSDRPRFYSWFAGRKRVGLVDPNRVTWLTRMMLNGIAINHHESAHTVVSTLALAPVIGIEPVSEVVAPGIGDDPARRARFDAWLAESPAIRDGKPLVVLHPYPMFRYKQWRLEGWIEMIEWLRTQGFAIALSGGPADREREYAEQVAAGAGGDVLNLVGRLTFGESAELVRRARLFIGPDTGATHVAAATGVDTIALFGPSDPVRWGPWPQHWPPTENPWALHGSARHGNVWLLQGEGDCVPCRQEGCERHVDSHSDCLVNLGTQRVKMAAAEMLGLNPPNAADAVIDTSRLHRARSD
>NC_010551.1|WP_012364358.1|2480242_2481523_+|O-antigen-ligase-family-protein
MLSFSAPATRRLTAARAFAVIALCMVPVSTALTNVFCGLFAAALVISPEFWRDLRSFVTDPAALAALLILAALTASVTYTVAPHPKAWNWIGKYDKLLLLPFAVLAFRHSNWAPIVRRAWFGTLCVILLLSTTNYLGLTAIGPAHASDLPLSRAWVFKNHIAAGMFGALLFYQAADLALSARTALSRAAYGAVAAWSLINVFVMLQGRTGQVIALLLILVVAVRFVLLLRRQSALRATLAAGTLVLAGVALVAAACTMQNGRLVKVVTEVQQYRQTDAATSTGLRLEWYKKGLELYRMRPVIGYGAGGLEFEFQKLTAGKTAAEGQLTSNPHNEYLLMAVQLGTLGVLLFVNLIVQIARGSRALDPRSQHLLLAWLAIFAIGSLANSLLLDFAEGHLLVLLAGILLGCAERGEALPRETSAIRRSA
>NC_010551.1|WP_012364357.1|2479263_2480106_+|glycosyltransferase
MFSIIIPTWNNLPYLKLVVDSLRRHSAYDHQIIVHVNDGSDGTLDWVRDEGIEHTASPTNIGICHAVNLAAARATRDYVVYMNDDMYCCPGWDAALVRRIEQMPTDLFMLSGTMVEPVDTRNPCVVVSNFGRDAEQFDAAGLVAATPRLARADWLGSTWPPTLVHRDWWNRIGGYSSELSPGMSSDNDFSMKFWDAGCRIFLGVGDSLVYHFQQKSTGKIVKNDGRRQFLNKWGMTQATFDRYYLHRGEPAGSRIALDTPTVDGRLKRALLRSRIKRAFS
>NC_010551.1|WP_012364356.1|2478366_2479119_+|glycosyltransferase-family-2-protein
MAEPTLGVALIALNAAARLAQCLDALTFADHIVVIDGGSTDDTVAIARAHGARVIVERDWPGFGPQKNRALAALDTDWILSLDTDEVVSPELAQSIRAAIRAPAAQVYALDRLSSFCGQWIRHSGWYPDWVPRLFRRGAARFSDDLVHERLVFDTPAQRLAGKLMHYSYEDFETVVRKLDAYSTAGARQRRAAGQRGGFGKALARGAWAFVRTYVLRRGFLDGRAGFMIAVFNAETVYYRFLKLGHEPAR
>NC_010551.1|WP_006752229.1|2476391_2478143_-|lipid-A-export-permease/ATP-binding-protein-MsbA
MDGTGTSPFTVLKRLWPYIRPLIGIVVLAVVTMGVVAATEAGIPALLKPLLDHGFGSHGSDRAKWYVPMAVIGLALVRGVSQYASNYLLNYVSNRILLQLRLEMFQRMLHTGASFFQRETASTVINAIVFEVNQILAVLTGVMVTLVRDSLTVMFLLGYLFYLNWRLTLIVAVILPGIGWLVSKINRRLRRLNREHQTLTNELSYIVEETVGGYKVVKVHNGETYEMDRFTAMSKRLRGYAMRMTISGGLAQPLTQFLASIALAVVITIAVVQSTNDQTTVGGFVAFVTSMLLVISPLKHLIDVNQPLQRGMTAAELIFGLIDEPGEPQGGGRALPHARGEIEFRGVSFDYGASERPTLDRISFKVAPGEMIALAGPSGSGKTTLVNLLPRFFDPTGGAILVDGVPVADYDLHALRGQMAMVSQDVVLFNDTIAANVAYGQTPDRARVQAALEAANLADAVAAMPDGLDTLVGGNGMRLSGGQRQRLAIARAIYKDAPILILDEATSALDSESERHVQAALERLMEGRTTLVIAHRLSTIERADRILVLEAGKIVEEGSHEELLRHGGLYAHLHRIQYQQQAA
>NC_010551.1|WP_006752228.1|2475914_2476295_-|RcnB-family-protein
MKKMHGTMLAALIVAGFAAPAAMAQGHGNDDNHGNHGMHRGHGPKHMPPGQMRHEDDVPPRWADQPHREWHKGDRLPGEFRDRQYVVEDWRGYHLSAPPRGYQWVGVGGDYLLVQIGSGIVLRVGP
>NC_010551.1|WP_012364354.1|2475294_2475861_+|FUSC-family-protein
MDTIRTLNEARQQIQQSIFDLFKGLTFGERLTQGALMALQAVCGACLAYAIGRALHTEQAVWAAVTAIAVTQHNYSDTMSLSRDQFIGAMIGGLLGFAGAALGGDRLVAYALAVALTIVSCWCLNVGSAARLGGVTATIVLLFPGNGPLWDIPLMRLGEVALGTVCALAVCWAMSLIERRWFHRAAAK
>NC_010551.1|WP_012364353.1|2474009_2475269_+|MFS-transporter
MTIKHSVTVRSLRSLDWLNFFVANVQTGFGPFIASYLASHKWTQGEIGMVLSIGTISAMVSQVPGGAAVDALKNKKGAAAWAIVAIILSAVLLASSPTIVPVIAAEVFHGFASCMLVPAMAAISFSLVGRADLGDRLGRNARWASIGSAVAAGLMGLTGEYFSARAVFWLTAVLALPALFALAMIQPTHEVIPQSSKSDDHDEGEHRETLLELLRDRRMLIFASCVVLFHLSNAAMLNLAAGEVTAGMGENVQLVIAACIIVPQAIVAMLSPWVGRSSQRWGRRPILLLGFSALPVRALLFAGVSSPYLLVPVQMLDGISAAVFGVMLPLIAADVAGGKGRYNLCIGLFGLAAGIGATLSTAVAGYVADHFGNTTSFFGLAAAGALAALLVWLAMPETRVDNGDVTAGEPADASPEQAH
>NC_010551.1|WP_012364352.1|2473044_2474013_+|PRC-barrel-domain-containing-protein
MSGGLPFPASRMSFPSSTVFLVLAAAALLSGCGLLPTQNPPAPISEALIEPVGETAGEPLTMPPVPAPTHPEEPEAPKKPHREVPRPKPVQRAEPPAPPPPPPPPLVATRPLDRTQIHALLDSEVARRNGKVIGRAVDMVIDASGKPREMIVNLQGFMGIGDRKVIFPWNVFRFTPGGKQEPIVLDVPSGDLPPAARPKAVPLSGSAAASPATRLPLLDSDVERPNGTKIGRIVDVLIDRAAQPQAVVLDLGGLVNTDRRSIAASWGALRFVTRDKALRPQLDLNDAQIKAAPPYAADKPIVAVYPPVAPAPVQASSASATR
>NC_010551.1|WP_041489837.1|2471596_2472775_+|collagen-like-triple-helix-repeat-containing-protein
MNAPTTHQAGLRMIMIAAGVAALMSLSACGGSGSLSKGTGGSGSGSGDTTASTGGTANGTSGTSASNGGTGGAGSTDGTGNGASGTSANGVGQTLAASSNIVTAGGGAISGVGTAIGSQTLPGTNPATTQGLGAVVQDVGAAVTTLGTGLGSGLGQLGASSNPVGTTVASTGGVVTDLGLAVAATGGVVSSLGASGSALAPLAPVTSPVGGAVTMLGNTIAGGGATLGTQLSTGPVAQVTGAASSAITPITTTVGSLTQTAAASTPLGAPLTNLVTTVGNGVANAGTTIAKTGNNPVTTGVGNVVTATGNTVATAGTALLGGGAAATNPLAPVTGLLSTGALGGTTSGSKPAGTLTSAVGGLTGGSGTGVLSNTGGGLLAPVTTTLGTLVKK
>NC_010551.1|WP_012364360.1|2483213_2484308_-|glycosyltransferase-family-9-protein
MANETPKRRILVIRIDFLGDMLCTTAFLGALKRRWPDAELHVVANRYNASALDGNPDVHAVHTYVYSRQCERNDRPGRMRAFFDRLRLVRRLRRLRFDLVVVPNGGMHRSSIQLARQLGVKDCRWHDADSEFDDRKPEHVASRPMCHEALSGFRLVPELGRNDLDGLALSVHPDRALLDTWYRLLGARAKPRVGLFVSNKATERRWPADRWCDLGRRLAPFADVIVFRDPAVSAGAGADGDAWRDVNARHVAPSSVAELVAAASLLDAIVSADSAPVHLASALGVPVAALFEDRPEKYRRWHPLGVPHMILRAGATVDAIGVDAVERAVLHLLEKAGQADDATGGALPLPDVTLVVPAVGAIVS
>NC_010551.1|WP_041489839.1|2484628_2488162_-|DNA-polymerase-III-subunit-alpha
MSDPRFVHLRVHSEFSIADGIVRLDDIVKAAAADGQGALALTDLGNAFGLVRFYQEARGKGIKPIAGCDVWITNPDDRDKPSRLLLLVKDKVGYLNLCELLSKAWLTNQYRGRAELDASWLDGELSQGLLALSGAQQGDIGLAFAAGNEEAARRHAERWAKVFPGGFYIELQRYGQPGAEAYIQQAATLAASLGLPVVATHPTQFMTDDDFTAHEARVCISEGDMLANPRRQKRFTTDQYFRTQDEMVALFADLPSAVANTVEIAKRCNLKLELGKPKLPLFPTPDGMSLDDYLVQLSKEGLEKRLEQLFPDTAERDAQRDTYYKRLEFECGTITKMGFPGYFLIVADFINWAKNNGVPVGPGRGSGAGSLVAYALGITDLDPLRYNLLFERFLNPERVSMPDFDIDFCQHGRDRVIQYVKEKYGADAVSQIATFGTMAAKAAVRDIGRVLDLGYMFTDGVAKLIPFKPGKHVTIADAMKEEPQLQERYDHEDEVHQLLDLAQRVEGLTRNVGMHAGGVLIAPGKLTDFCPLYTQGDDGGVVSQYDKDDVEAVGLVKFDFLGLTTLTILDWAERYIRRLDASKADWSLAQVPLDDPASFQILKKANTVAVFQLESRGMQGMLKDAQPDRFEDIIALVSLYRPGPMDLIPSFCARKHGREKVEYPDPRVEPVLKETYGIMVYQEQVMQMAQIIGGYSLGGADLLRRAMGKKKPEEMVKHREIFAEGAAKNGLTREKSDEIFDLMEKFAGYGFNKSHAAAYALLAYYTAWLKAHHPAEFMAANMTLAMDDTDKVKILFDDCVVNNLVVLPPDINQSHYRFEPVGEADGKRSRTIRYGLGAVKGSGQNAIEEILRAREEKPFTDLFDFCERIDRRVVNRRTVEALIRAGAFDSLNANRAQMLASVPLAMEAAEQAAANAMQAGLFDMGAESPHAHALVDEPAWDDKRRLQEEKGALGFYLSGHLFDAYRDEVRRFVRQKIGDLKEGRDKLVAGIIASLRTQMTQRGKMLIALLDDGSGQCEITIFNEQFEANKALFKEDELLIVQGQARNDAFTGGLRFTADTVMDLERARSRYAQAVRLTMNGNADAAALRRVLEPHVSKDDSAAAPAFEAPVPRGGGRDGGRRPQAPLPNGLAVQVHYSNARAQGEMRLGDAWRVKPSDTLLAELRATFDGSVVEITY
>NC_010551.1|WP_011657537.1|2488384_2489239_+|sulfurtransferase
MTIVNLAAYHFVSIDATEQWRPLVTARCNELGLRGTILLAPEGINLFIAGPREATDAFIDYIRHDPLFEGKFATLQFKESLSDSQPFRRMLVRLKREIITMKKPAIKPELGRAPSVDARTLKAWLDRGHDDAGRPVVMLDTRNAFEVDVGTFDGALDYRIDKFSEFPEVIDANRADLEGRTVVSFCTGGIRCEKAAIHMKEIGIDNVYQLEGGILKYFEEVGGAHYHGDCFVFDYRTALNPQLQPTENVTCFACRAVVTPEAQQSPSYVPGKSCPACAQAASAA
>NC_010551.1|WP_012364362.1|2489261_2490146_+|tRNA-glutamyl-Q(34)-synthetase-GluQRS
MNGYRGRFAPSPTGPLHFGSLVGALASWLDARAHGGAWLVRIEDIDRPRTVPGAADDILATLAHFGMTPDEPPVWQSTRDAEYAAALERLVAAGRVYPCGCTRKEIADSLRAAHERHTTLAYPGTCRTGLHGKPARAWRLRVPDGDDANVTFDDRWQHTQTQNLATEVGDFVLKRADGQWAYQLAVVVDDADAGITHVVRGADLLDSTARQIYLQRCLGVPTPAYLHVPVVVDANGEKLSKQTGAIALERDDPLPALRAAAAHLGLAVDCDPSGDTMDAFYAAATDAWARRFAQ
>NC_010551.1|WP_012364363.1|2490224_2491760_-|DEAD/DEAH-box-helicase
MSAGPAGLTHDVPAAPFERNATMSDSVAKPVDATFDQFGLAADILKAIAEQGYTTPTPIQAQAIPVVLAGRDVMGAAQTGTGKTASFSLPIIQRLLPQASTSASPARHPVRALILTPTRELADQVAANVHAYAKHTSLRSAVVFGGVDMNPQMAELRRGVEILIATPGRLLDHVQQKTANLGQVQILVLDEADRMLDMGFLPDLQRILNLLPKERQTLLFSATFSPEIKKLASTYLRNPQTIEVARSNSTNANVTQIVYDVAEGDKHGAVVQLLRDRGLKQVLVFCNSKIGASRLARNLERDGVVASAIHGDKSQLERMQALDAFKRGEIEALVATDVAARGLDIAELPAVINFDLPFNAEDYVHRIGRTGRAGATGDALSLCSPNERKQLADIEKLIKRPLEVQTLALDKPSRHRHDERGGERGGERGGRRERDEHRGASARRSGSSERGGHHRRHEAPVDDFFLKPYEPSVPATQPEETQSAQQHEKKGPKRQVAALLGGFGMPRKPSA
>NC_010551.1|WP_012364364.1|2492205_2492589_-|lysozyme-inhibitor
MIRQTFAALALAGSAVSVAHAAQLTVEEIDADAREQTIYQCANLKRPVRVSYWRAANGQSFALVPVNGQQLLFVDTVSASGARYQAGRYTWWTKGREGTLRDEIADQNAAPLLGDCMQVEKKKKKKG
>NC_010551.1|WP_012364365.1|2492687_2492882_-|hypothetical-protein
MASTWRWIGRIGRLGAALALIASLTGCGLAAAPCRVASAGLKIVPLVGHVAAAPTDACADVIDP
>NC_010551.1|WP_012364366.1|2492900_2494115_-|formate-dependent-phosphoribosylglycinamide-formyltransferase
MQIGQRLGTPLSPSATRVMLLGAGELGKEVIIALQRLGVEVVAVDRYPDAPGHQVAHRAHVIDMTDAAALRAVVEAERPHLIVPEIEAIATDALAAIEAAGLAEVIPTARATQLTMNREGIRRLAAEELGLATSPYAFADSFDAFSAAVAKIGMPCVVKPVMSSSGKGQSVVRTEADVKPAWDYAMAGGRVNHGRVIVEGFIDFEYEITQLTVRAIDPATLETRTYFCEPVGHVQVAGDYVESWQPQPMSALALKKSREIAHKVTEALGGRGLFGVELFVRGDDVWFSEVSPRPHDTGLVTLASQRQSEFELHARAILGLPVDPTLGSPAASAVIYGGLDERGIAFEGVRDALAVPGADLRLFGKPESFAKRRMGVALAIGASVDEARERAKRAAAAVRPVSAR
>NC_010551.1|WP_012364367.1|2494331_2494877_+|META-domain-containing-protein
MSHLSAAARARTGLLRPLRAPLCALTLATLLAACAMPTHPDSAAPAPDPYNPAAVQLLDDTSWELTSWLNADGTSRTIPHGDNGEPIKLALSTESGVRRASGFSGCNRYMGTYALKNGLLNFGPLAGTRMACPNALGGQLEHAYLDALAHIEKTGVQMREPQQLQIVTEAGATLTFTRRSP
>NC_010551.1|WP_012364368.1|2495056_2499889_+|DNA-translocase-FtsK
MHTVVIGWFGISAVWFLLLFWRLVQAMLPGGGGLAGRGSIRLWLGFAAVLVASCALTSPLSGPDTNALGHAFSNGFAHVLGPIGTPVAMVVLFFAGLPWLTGIGWRRFAAWVDTSFGVKLARDVDDDDVRGVADLPRSALHRDDDLVQPTTAHTVNSMAPRQNGRYSRPTVWKPDPQARPTPRSKPAPRPLAEPVAPSGWLKPTPASRMPAPPAPGAASAMPPPTTGSTASLARAAANAQVPRPSPAPLPAGFEPVRPQPTAARPATAALKQPAAPRTAVTPRPVGAPPRTPARPVTGAGAGAGGQSQDAARRRPTPPAPARAPLYAWVQQPAEPITPAPSVHDTLRSIEASTAQWAALDGVRPTDASPATAAGATVATVAGTVAAAGSVAAVASSASAASMASTALTGSIASMTSTAVPAGVVQDVRQFAPHDAGRPDAHEAASAYDDNAPIVLDAFMPAEPTVRAPAVDAVDAIDTGTSTSSDAARHAMSDSAVEADAPTRHADGEHRHDVDAPAAPAFDAPVDFAPWEDIVSSPVSGLGESHQSPVATPLSATREPLAAHAAVEAPAAAVTPTANDTRCTVDAKDTAMAAGIVGHFRPQSAPAADTGVSVEAKQHAHANLNDVKPVQQVAPSAPLPASSIAATPMRTPADAMPVAAATTAPFAASNAALADTVTGTVWKAPEKPTGETAPLPADTQRATPASAAPTFASIEPASVDSAAPASWSKPLSAEPFAAAPTAPVAGTPSHIGTTSGSAVPAPANTSNSTPLAATPSFAGMTNTASGSLSQPGASVAASVPTSAVGASSPTTAPSSVSAPFAAAAPPATSATSAPPATGASGMLTAPPAATAPTVTASSAPASTGASFNAAASQPTPSTPVSPAAASGSTFTATSSASATPSAAPSSRMPDASAIGQPSVSTATAQTATSGTAPAAAADVAAFPASSSGTLAPTTPIAAASPTAFGGTPASPSGAFVSVAATPTATAPATPPTSASPSASALPIASVPGASSIDASTPTPPIAPTPAPQAQPFAAPPAPAAAPSSWAMPGAGATPTSTGTAIPACTIAPLPPATLPAATLPTAAEPAALAEPSAPAPDAPSAPERPPRPNAFEFHAPASFNVELPTLDLLEPASFDVEPITEEHLAQTAQVIEQRLQEFKVPVTVVGASAGPVITRFEIEPALGVRGSQIVGLMKDLSRGLGLTSIRVVETIPGKTCMGLELPNAKRQMIRLSEILESRQYQHSTSQLTIAMGKDITGHPVVTDLAKAPHMLVAGTTGSGKSVAINAMILSLLYKATPEDVRLIMIDPKMLELSVYEGIPHLLAPVVTDMKLAANALNWCVGEMEKRYRLMSAVGVRNLAGFNQKIRDAEAKEKKIGNPFSLTPEDPEPLSKLPLIVVVIDELADLMMVAGKKIEELIARLAQKARAAGIHLILATQRPSVDVITGLIKANIPTRVAFQVSSKIDSRTILDQMGAESLLGQGDMLFLPPGTGYPQRVHGAFVADEEVHRIVEYLKQFGEPQYEEGILDGPAADGATQDLFGDAPDAEADPLYDEAVAFVVRTRRASISSVQRQLRIGYNRAARLVEQMEAAGLVSAMGINGSREVLVPAAAD

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Crispr_ID: NC_010551_5

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_010551_5

3095071-3095142

Orphan

Consensus_repeat	Method
GGTCCCATGCTTCGCGGTCGACC	CRISPRCasFinder

1 spacers

The CRISPR arrays of NC_010551_5

>merge|NC_010551|5|3095071-3095142|CRISPRCasFinder
GGTCCCATGCTTCGCGGTCGACCAGAGTTAGTGCTTTAGCACTTACCCGGGTCCCATGCTTCGCAGTCGACC

>NC_010551|5|5|3095071-3095142|CRISPRCasFinder
GGTCCCATGCTTCGCGGTCGACC	AGAGTTAGTGCTTTAGCACTTACCCG
GGTCCCATGCTTCGCAGTCGACC

Protein	Signature genes	Signature genes Name	Protein_function
NC_010551.1\|WP_012364790.1\|3098886_3101022_-\|3-hydroxyacyl-CoA-dehydrogenase	unknown	unknown	gnl\|CDD\|236864
NC_010551.1\|WP_012364786.1\|3094718_3095024_-\|DUF485-domain-containing-protein	unknown	unknown	gnl\|CDD\|377315
NC_010551.1\|WP_012364785.1\|3093016_3094702_-\|cation-acetate-symporter	unknown	unknown	gnl\|CDD\|236495
NC_010551.1\|WP_012364788.1\|3096500_3097646_-\|acyl-CoA-dehydrogenase	unknown	unknown	gnl\|CDD\|132247
NC_010551.1\|WP_006753858.1\|3104441_3105434_-\|lipoyl-synthase	unknown	unknown	gnl\|CDD\|235493
NC_010551.1\|WP_012364783.1\|3089333_3091367_-\|sensor-histidine-kinase	unknown	unknown	gnl\|CDD\|226654
NC_010551.1\|WP_012364781.1\|3086545_3087118_-\|hypothetical-protein	unknown	unknown	unknown
NC_010551.1\|WP_006753861.1\|3106694_3107666_+\|transcriptional-regulator-GcvA	unknown	unknown	gnl\|CDD\|182990
NC_010551.1\|WP_006489451.1\|3084111_3084363_+\|accessory-factor-UbiK-family-protein	unknown	unknown	gnl\|CDD\|377337
NC_010551.1\|WP_012364793.1\|3105426_3106182_-\|lipoyl(octanoyl)-transferase-LipB	unknown	unknown	gnl\|CDD\|237682
NC_010551.1\|WP_012364782.1\|3087278_3087815_+\|TlpA-family-protein-disulfide-reductase	unknown	unknown	gnl\|CDD\|239264
NC_010551.1\|WP_012364791.1\|3101250_3102213_+\|LysR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|176114
NC_010551.1\|WP_012364792.1\|3102283_3104164_+\|gamma-glutamyltransferase	unknown	unknown	gnl\|CDD\|223482
NC_010551.1\|WP_012364794.1\|3106265_3106592_-\|DUF2917-domain-containing-protein	unknown	unknown	gnl\|CDD\|378568
NC_010551.1\|WP_012364780.1\|3084625_3086212_+\|YifB-family-Mg-chelatase-like-AAA-ATPase	unknown	unknown	gnl\|CDD\|223679
NC_010551.1\|WP_006398175.1\|3083416_3083755_-\|P-II-family-nitrogen-regulator	unknown	unknown	gnl\|CDD\|223424
NC_010551.1\|WP_012364789.1\|3097660_3098857_-\|acyl-CoA-dehydrogenase	unknown	unknown	gnl\|CDD\|132248
NC_010551.1\|WP_011658019.1\|3087896_3089252_-\|sigma-54-dependent-Fis-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|225114
NC_010551.1\|WP_012364784.1\|3091371_3092661_-\|dicarboxylate/amino-acid:cation-symporter	unknown	unknown	gnl\|CDD\|234968
NC_010551.1\|WP_012364787.1\|3095264_3096470_-\|CoA-transferase	unknown	unknown	gnl\|CDD\|367110

Protein	Function_ID	Function_description	E-value
NC_010551.1\|WP_012364790.1\|3098886_3101022_-\|3-hydroxyacyl-CoA-dehydrogenase	gnl\|CDD\|236864	PRK11154, fadJ, fatty acid oxidation complex subunit alpha FadJ.	3.5204e-157
NC_010551.1\|WP_012364786.1\|3094718_3095024_-\|DUF485-domain-containing-protein	gnl\|CDD\|377315	pfam04341, DUF485, Protein of unknown function, DUF485. This family includes several putative integral membrane proteins.	3.11364e-27
NC_010551.1\|WP_012364785.1\|3093016_3094702_-\|cation-acetate-symporter	gnl\|CDD\|236495	PRK09395, actP, cation/acetate symporter ActP.	0
NC_010551.1\|WP_012364788.1\|3096500_3097646_-\|acyl-CoA-dehydrogenase	gnl\|CDD\|132247	TIGR03203, pimD_small, pimeloyl-CoA dehydrogenase, small subunit. Members of this protein family are the PimD proteins of species such as Rhodopseudomonas palustris, Bradyrhizobium japonicum. The pimFABCDE operon encodes proteins for the metabolism of straight chain dicarboxylates of seven to fourteen carbons. Especially relevant is pimeloyl-CoA, basis of the gene symbol, as it is a catabolite of benzoyl-CoA degradation, which occurs in Rhodopseudomonas palustris.	5.33339e-99
NC_010551.1\|WP_006753858.1\|3104441_3105434_-\|lipoyl-synthase	gnl\|CDD\|235493	PRK05481, PRK05481, lipoyl synthase; Provisional.	0
NC_010551.1\|WP_012364783.1\|3089333_3091367_-\|sensor-histidine-kinase	gnl\|CDD\|226654	COG4191, COG4191, Signal transduction histidine kinase regulating C4-dicarboxylate transport system [Signal transduction mechanisms].	0
NC_010551.1\|WP_012364793.1\|3105426_3106182_-\|lipoyl(octanoyl)-transferase-LipB	gnl\|CDD\|237682	PRK14343, PRK14343, lipoyl(octanoyl) transferase LipB.	1.85926e-158
NC_010551.1\|WP_006753861.1\|3106694_3107666_+\|transcriptional-regulator-GcvA	gnl\|CDD\|182990	PRK11139, PRK11139, DNA-binding transcriptional activator GcvA; Provisional.	1.17623e-171
NC_010551.1\|WP_006489451.1\|3084111_3084363_+\|accessory-factor-UbiK-family-protein	gnl\|CDD\|377337	pfam04380, BMFP, Membrane fusogenic activity. BMFP consists of two structural domains, a coiled-coil C-terminal domain via which the protein self-associates as a trimer, and an N-terminal domain disordered at neutral pH but adopting an amphipathic alpha-helical structure in the presence of phospholipid vesicles, high ionic strength, acidic pH or SDS. BMFP interacts with phospholipid vesicles though the predicted amphipathic alpha-helix induced in the N-terminal half of the protein and promotes aggregation and fusion of vesicles in vitro.	1.72724e-20
NC_010551.1\|WP_012364782.1\|3087278_3087815_+\|TlpA-family-protein-disulfide-reductase	gnl\|CDD\|239264	cd02966, TlpA_like_family, TlpA-like family; composed of TlpA, ResA, DsbE and similar proteins. TlpA, ResA and DsbE are bacterial protein disulfide reductases with important roles in cytochrome maturation. They are membrane-anchored proteins with a soluble TRX domain containing a CXXC motif located in the periplasm. The TRX domains of this family contain an insert, approximately 25 residues in length, which correspond to an extra alpha helix and a beta strand when compared with TRX. TlpA catalyzes an essential reaction in the biogenesis of cytochrome aa3, while ResA and DsbE are essential proteins in cytochrome c maturation. Also included in this family are proteins containing a TlpA-like TRX domain with domain architectures similar to E. coli DipZ protein, and the N-terminal TRX domain of PilB protein from Neisseria which acts as a disulfide reductase that can recylce methionine sulfoxide reductases.	4.92024e-41
NC_010551.1\|WP_012364791.1\|3101250_3102213_+\|LysR-family-transcriptional-regulator	gnl\|CDD\|176114	cd08422, PBP2_CrgA_like, The C-terminal substrate binding domain of LysR-type transcriptional regulator CrgA and its related homologs, contains the type 2 periplasmic binding domain. This CD includes the substrate binding domain of LysR-type transcriptional regulator (LTTR) CrgA and its related homologs. The LTTRs are acting as both auto-repressors and activators of target promoters, controlling operons involved in a wide variety of cellular processes such as amino acid biosynthesis, CO2 fixation, antibiotic resistance, degradation of aromatic compounds, nodule formation of nitrogen-fixing bacteria, and synthesis of virulence factors, to name a few. In contrast to the tetrameric form of other LTTRs, CrgA from Neisseria meningitides assembles into an octameric ring, which can bind up to four 63-bp DNA oligonucleotides. Phylogenetic cluster analysis further showed that the CrgA-like regulators form a subclass of the LTTRs that function as octamers. The CrgA is an auto-repressor of its own gene and activates the expression of the mdaB gene which coding for an NADPH-quinone reductase and that its action is increased by MBL (alpha-methylene-gamma-butyrolactone), an inducer of NADPH-quinone oxidoreductase. The structural topology of this substrate-binding domain is most similar to that of the type 2 periplasmic binding proteins (PBP2), which are responsible for the uptake of a variety of substrates such as phosphate, sulfate, polysaccharides, lysine/arginine/ornithine, and histidine. The PBP2 bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap. After binding their specific ligand with high affinity, they can interact with a cognate membrane transport complex comprised of two integral membrane domains and two cytoplasmically located ATPase domains. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis.	6.15784e-50
NC_010551.1\|WP_012364792.1\|3102283_3104164_+\|gamma-glutamyltransferase	gnl\|CDD\|223482	COG0405, Ggt, Gamma-glutamyltransferase [Amino acid transport and metabolism].	0
NC_010551.1\|WP_012364794.1\|3106265_3106592_-\|DUF2917-domain-containing-protein	gnl\|CDD\|378568	pfam11142, DUF2917, Protein of unknown function (DUF2917). This bacterial family of proteins appears to be restricted to Proteobacteria.	6.92206e-18
NC_010551.1\|WP_012364780.1\|3084625_3086212_+\|YifB-family-Mg-chelatase-like-AAA-ATPase	gnl\|CDD\|223679	COG0606, COG0606, Predicted ATPase with chaperone activity [Posttranslational modification, protein turnover, chaperones].	0
NC_010551.1\|WP_006398175.1\|3083416_3083755_-\|P-II-family-nitrogen-regulator	gnl\|CDD\|223424	COG0347, GlnK, Nitrogen regulatory protein PII [Amino acid transport and metabolism].	3.62827e-59
NC_010551.1\|WP_012364789.1\|3097660_3098857_-\|acyl-CoA-dehydrogenase	gnl\|CDD\|132248	TIGR03204, pimC_large, pimeloyl-CoA dehydrogenase, large subunit. Members of this protein family are the PimC proteins of species such as Rhodopseudomonas palustris and Bradyrhizobium japonicum. The pimFABCDE operon encodes proteins for the metabolism of straight chain dicarboxylates of seven to fourteen carbons. Especially relevant is pimeloyl-CoA, basis of the gene symbol, as it is a catabolite of benzoyl-CoA degradation, which occurs in Rhodopseudomonas palustris.	6.09404e-157
NC_010551.1\|WP_011658019.1\|3087896_3089252_-\|sigma-54-dependent-Fis-family-transcriptional-regulator	gnl\|CDD\|225114	COG2204, AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains [Signal transduction mechanisms].	0
NC_010551.1\|WP_012364784.1\|3091371_3092661_-\|dicarboxylate/amino-acid:cation-symporter	gnl\|CDD\|234968	PRK01663, PRK01663, C4-dicarboxylate transporter DctA; Reviewed.	0
NC_010551.1\|WP_012364787.1\|3095264_3096470_-\|CoA-transferase	gnl\|CDD\|367110	pfam02515, CoA_transf_3, CoA-transferase family III. CoA-transferases are found in organisms from all lines of descent. Most of these enzymes belong to two well-known enzyme families, but recent work on unusual biochemical pathways of anaerobic bacteria has revealed the existence of a third family of CoA-transferases. The members of this enzyme family differ in sequence and reaction mechanism from CoA-transferases of the other families. Currently known enzymes of the new family are a formyl-CoA: oxalate CoA-transferase, a succinyl-CoA: (R)-benzylsuccinate CoA-transferase, an (E)-cinnamoyl-CoA: (R)-phenyllactate CoA-transferase, and a butyrobetainyl-CoA: (R)-carnitine CoA-transferase. In addition, a large number of proteins of unknown or differently annotated function from Bacteria, Archaea and Eukarya apparently belong to this enzyme family. Properties and reaction mechanisms of the CoA-transferases of family III are described and compared to those of the previously known CoA-transferases.	6.55464e-147

>NC_010551.1|WP_012364786.1|3094718_3095024_-|DUF485-domain-containing-protein
MELSVIESVTACRDYQQLVRARRRFSFTLTALMIATYYGFILLVALAPHVLAAPLYHGATTTVGIVAGVAIILVAIGLTAWYVLRANRAFDRRVAAILQRS
>NC_010551.1|WP_012364785.1|3093016_3094702_-|cation-acetate-symporter
MRLTSSALGALAVLVSSAAHASSVAGPMPDKVELNPVAIAMFFAFVFATLALTRWAARRTRSTRDFYTAGGGITGLQNGLAIAGDYMSAASFLGLSGMVFMFGFDGLIYSIGFLVGWPFVMFLIAEPLRNLGKFTFVDVVAYRFAQRPIRLLTSANALTIVVLYLVVQMVGAGKLIQLLFGLSYGTAELIVGVLMVVYVFFGGMTATTWVQVIKAVLLLCGATLLVLLALGEFGFSIDEMFRRAVAVHPGALSIMGPGKLIRDPANALSLGIALMFGTAGFPHILMRFFTVPNAKEARKSVLYATGFIGYFYLLTFVIGFSAIVLLAQHPEFFRLGANGTFNLTHDLLGGSNMVAVKLAQAVGGNWFYGFIAAVTFATILAVVAGLTLAGATTISHDLYAQMWARGKPDERLEMRISRAATIGLSAIAIALSILFEHVNVAFMVGLVAAVAASANFPVLAMSIFWRGMTTRGAVLGGGLGLASAVALTVLSKSVWVDVLHHAHAPVFLDNPALVSVPLAFVGIVVGSLADRGERARRERDAFAQQEFYAQTGVLASRAVQH
>NC_010551.1|WP_012364784.1|3091371_3092661_-|dicarboxylate/amino-acid:cation-symporter
MKKKPFYKVLYVQVIFAIIVGVILGHFYPALATDMKPLGDGFIKLIKMVIGPIIFCTVVTGIAGMEDMKKVGRVGGKALLYFEVVSTFALLLGLAATHILRPGVGFNIDPATLDGKAVASYAAKAHGQSTVDFLLHIIPNTMVDAFAQGEILQILLIALLFGSVLAHLGERGKVVTDFIDGLTRVLFGIVHIVTKLAPIGAFGAMAFTIGKYGVGSLVPLLKLIGTFYLTSIVFVLVVLGTIARVTGFSIIRFVSYIKEELLIVLGTSSSEAALPQLMEKLEKAGCSRSVVGLVVPTGYSFNLDGTNIYMTMAVLFIAQATNIELTWMQQLTLLAVAMLTSKGASGVTGAGFITLAATLAVVPTIPLSGMVLILGIDRFMSECRALTNIVGNGVATVVVSAWEKELDRNKLRQALAGGGEVKTTEAAGV
>NC_010551.1|WP_012364783.1|3089333_3091367_-|sensor-histidine-kinase
MNEQAAVPPAAAAPRGGPGGRAGDAEPYDTIGDPHRQEVTSVKRRLLILVVLAVALAAACALTWTITWRRGVAELQRNAAVRVDRTTNALKSTLDRYESLPYLLGSHPYVQDLLAEPKRTDFTGRANRYLEDLNEHAHATVTYVVGADGLCVAASNWRAPDSFVGIEYRFRPYFIDAMNGRVGRFFGIGTISRDPGYYISQPVRRDGKIVGVVVVKLNLEWFQGADASEPLVVADDHGVVFLSSVPAWKYHTLHPLTGPVAASIYETRQYAQQPVTPLPLRVEQVLGADAEIVRLGAAGVGPGLRAPRFLASKRRIGEPDWLLVTLAPIAPIDADARNATIVTGFGFVSVALLAFYWRMRRARVREMIRGRALLQQAYAELNRRVEERTADLSEANEQLQKEVGDRIRAEQELRAAHDELIQASKLAALGQMAAGITHELNQPLAALRSFSDNTRVLLDRGEQAAARENLEAIAALTERMGKITNQLKLFVGRAKPRNEQALVVRALRSVLSLLGERLRGVALTLTLQDATVSPAQDAPLDLARDYPDLVARCEDLRLEQVLINLLGNALDAVAGVTAPAIEVTIAVSVATLAVEVRDNGPGIAPDLLPRLFEPFFTTKEMGRGLGLGLAISSSIASDAGGALTARNAPSGGALFVLTLRRTRTHHPDSLSEPAGSR
>NC_010551.1|WP_011658019.1|3087896_3089252_-|sigma-54-dependent-Fis-family-transcriptional-regulator
MANRLQVIYIEDDALVRRASVQSLQLAGFDVVGFESAEAADKAIVAETAGVIVSDIRLPGASGLDLLAQCRERVPDVPVILVTGHGDISMAVQAMRDGAYDFIEKPFAAERLIETVRRALERRELVLENHALRRELAGQNIVAPRIIGRSPAIEQVRKLIANVAPTDASVLINGDTGAGKELIARSLHELSPRRDKPFIAVNCGALPEPMFESEMFGYEPGAFTGAAKRRVGKLEYASGGTLFLDEIESMPLALQVKLLRVLQDGVLERLGSNQPIRVNCRVVAAAKGDMSELVAAGTFRRDLLYRLNVVTIALPPLAERREDIVPLFEHFMLDAAVRYGRPAPVLTDRQRASLMQRDWPGNVRELRNAADRFVLGVADMPQDAGASGDDAESDQTLKERIEQFERAVIAQALNQTGGAVAATADRLHVGKATLYEKMKRYGLSAKGETER
>NC_010551.1|WP_012364782.1|3087278_3087815_+|TlpA-family-protein-disulfide-reductase
MNTTPPAQRRTGPARYIVAAVVVAAIAVAGFFAFNGRSSVPDATFTLLSGQKVSTAGDLKGKVYLVNFWATSCATCMQEMPQMVETYNRFKGQGLEFVAVAMNYDPPMYVANYAQTRQLPFKVALDDGSVAKQFGNVQLTPTTFVVDKNGKILKRYVGAPQFAELDALLKKALDGNAA
>NC_010551.1|WP_012364781.1|3086545_3087118_-|hypothetical-protein
MPKEVIDSLRPLFRPLRHFAALACVSAALAACSPSYDWRTLHNDAGYTIDLPAKPTVEDHPIAVGGASMPMRMQAAHVDGAVFAVGTLMLPDDRDDTRRAALEFLRAGLSRNLDGAPRTASVPVPLAAGGAVNGLELRIAGAASGGDHAHKTIVARLVARGRHAYQAVVIADGPLAQEQLDQFFGSFKLD
>NC_010551.1|WP_012364780.1|3084625_3086212_+|YifB-family-Mg-chelatase-like-AAA-ATPase
MSLAVVRSRAPAAGRAPDVTVEVHLANGLPSFSIVGLPDLEVRESRERVRAALQNCGFEFPVRRITVNLAPADLPKESGRFDLPIALGILAANGQIPADALAGREFAGELSLTGALRPMRGAFAMACGAARDWRAGETGPGVGSGAMSDPAAASRPPELYLPLDSAAEAALVPGVTVFGAPDLPALCAHLAGAPDARLAPVAAPCLDGEPAPAAPDLADVIGQRGARRALEVAAAGGHHMLMIGPPGAGKSMLAARLPGLLPPLTDDEALTSAALLSASRIGFSPAQWRRRPFRSPHHSSSAAALVGGRNPPQPGEITLAHLGVLFLDELPEFDRHVLEMLREPLEVGRITISRAAQQADFPAACQLIAAMNPCPCGWHGDPSGRCRCSPDVASRYLRKLSGPLLDRIDIQIDLPALSPAELAARATAHGESSATVAARVAQARALQFERQGKTNHMLSGRETDDLCRPTDDGERLLREAGERFGWSARAYFRVLKVARTIADLAGDPFPTAAQIAEAIRYRRALTAL
>NC_010551.1|WP_006489451.1|3084111_3084363_+|accessory-factor-UbiK-family-protein
MKQPSDVFNDLQSRVSDLLKNSPAKDVERNVKAMLSQGFSKLDLVTREEFDTQAQVLARTRVRLEELEKRVAELEQKLAAPQA
>NC_010551.1|WP_006398175.1|3083416_3083755_-|P-II-family-nitrogen-regulator
MKLITAIIKPFKLDETREALSALGVSGITVTEVKGFGRQKGHTELYRGAEYVVDFLPKMKIEAAVSDDLVDQAVEAIERAARTGKIGDGKIFVTPIEQVIRIRTGETGADAL
>NC_010551.1|WP_012364787.1|3095264_3096470_-|CoA-transferase
MTNDPRALPLAGVKVLDFSRVLAGPWSAMVLADFGADVIKIEHPARGDDTRDWGLRIGDTETTYFNSVNRSKRSICVDLQTEAGRRIARELAAQADVLIHNFKAGGAEKLGLGYDALAELNPRLVHCAISGYDRSGPEAARPGYDLVVQGEAGLMALNGEAGQPPLKFGVAAVDLFTGMYSAQAILAALYERHATGRGRRIEMALFDCGLMITAYYGLDALLMGEDPPRYGNAHPSIVPYGVFDAADGPLVITVGNNTQFARFCDAIERPDLAADERYRTNLGRSANRAELLPELRRELARRPRATLLAALSGAGIPCGEVLGLHDALTSERATRAGLVTRQPHPVAGGVDVLAPPYRFDGARLPVRGAPPVLGADTDDVLGGWLGMSTDELARLRADRIV
>NC_010551.1|WP_012364788.1|3096500_3097646_-|acyl-CoA-dehydrogenase
MDFQHTEDRRMLADTLNRFIAEQYAFPVRDRIAQSADGFDRTMWQRFAELGAVGALFAEADGGFGGTGFDIAVVFECLGRGLVVEPFLGALLAGRALSLAGGAAHRERLAALIDGSASAAFAHDEPGSHYELTTVRTRAERAGDGWVLTGAKGVVDQAAQAAFFVVSARVSGHDDDAAGIGLFVVPADAPGVSLRDYRKIDGGRAAEVRFGRVALPADAALGGPSAHDGEAGAALLERVLGYGLLALSAEALGAMDIAKEYTLDYLRTRKQFGMAIGSFQALQHRMADLLLEVEQARSAVINAAAQLDAPRAARERALAAAKYSIGRIGTLVAEESIQLHGGIGMTWELPLSHYAKRLVMIDHQLGDEDHHLARYIALSKQ
>NC_010551.1|WP_012364789.1|3097660_3098857_-|acyl-CoA-dehydrogenase
MDLNFTPEEEAFRADVQRFLAAELPARTARKVKGGLHLTRDDMREWHAILNARGWLASHWPREFGGPGWSVAQKFLFDNECALAGAPRIVPFGVNMLGPVLIKYGSEAQQRHWLPRILDGTDWWCQGYSEPGAGSDLASVKTSAVRHGDHYVVNGQKTWTTLGHYANMIFCLVRTATDVRKQEGISFLLIDMNTPGVEVRPIITFDGEHEVNEVFFTDVRVPVENLVGEENRGWTCAKYLLTYERTNIAGIGFSTAALERLRAVAAKVTKNGRPLADDPFFAARVARVEIELENMRTTNLRVLAAVAGGGVPGAESSMLKIRGTQIRQEITALMRRAMGPYAQPFVDGALDADYAGEPVGPEEAPSAAQQYFNNRKLSIFGGSNEIQKNIIAKMMLGL
>NC_010551.1|WP_012364790.1|3098886_3101022_-|3-hydroxyacyl-CoA-dehydrogenase
MNSTAFPEPSRAGTVTRERRDKVLVVTIDHPPVNALSADVRRGLADALDAAQTDDAIRAVLIVGAGRNFIAGADIREFGKPPVPPSLPDVCEQIESSAKPVVVALHGATLGGGLEVALAAHYRLAVPGAKLGLPEVTLGLLPGAGGTQRAPRLIGAKAALDLMLTGRHASADEALALGLVDRLAHSDDTLAEGLAYAQELVSLGAPARRTREARGLADRASAQAAIDAARADLPKKSRGLFSPAKIVDAVEAALTQSFDAGMKLERSLFLQCIDSPQRAGLVHAFFAEREAAKAPEARRASARPVERIGVVGGGTMGAGIAVAALDAGLPVTMIERDEASLARGRAHVEKVYDGLVAKGRMTPAAHAARLARFKGSTSYDALAQADVVIEAVFEDMAVKKAVFAELARVCKPGAVLATNTSYLDIDELAATIDRPADVVGLHFFSPANVMKLLEIVVPARVSAEVVATAFALAKQLKKTPVRAGVCDGFIGNRILAVYRTAADYLMEDGASPYQIDRAVREFGFPMGPFQVVDLAGGDIGWATRKRRAATRDPRARYVEISDRLCERGWFGQKTARGYYLYPDGARVGTPDPEVEAIAADERAKKGITPRAFSDDEILRRYLAAMINEGANVVHEKIALRPLDVDAVFLHGYGFPRYRGGPMHYADTVGLANVLADIRAFANEDPLFWKPSPLIVELVERGADFASLNHID
>NC_010551.1|WP_012364791.1|3101250_3102213_+|LysR-family-transcriptional-regulator
MDLNALTLLVEILDAGNLSKAAQRLKVSRANVSYRLNQLERSIGQQLVRRTTRRIEPTEIGLKLYEHGRRIRNELLAAQESVTTLGQDLQGRVRLSVPSGYGQMVMSDWLLAFKRLHPGIVLDVVFENRVEDLMRDEIDIAVRVMPEPPQNLVARDMGAVRYVACASAAFAAAHGMPASLGALAAAPVVTATVMGRQLRIAAYLGDERHEVLLEPTLISENFLFLRQAILAGIGVGIVPDYVVQDDMRRGTVVTSLDAYRLSIFGTHMYMLYMPNRHHTRATATFIEFILEQAGKTGRGGPGAMRQGFLSDDNPPAARRQ
>NC_010551.1|WP_012364792.1|3102283_3104164_+|gamma-glutamyltransferase
MFDRIRPHSRPWTLPAAVAFALAAFGAGCTSPSAPSGAVVPVAAASGAAVPLPGVHAPELSSGWTDKPGWTSQHAMIAAANPLATQAGYDMLKAGGTAIDAAIATQMVLALVEPQSSGIGGGAFMLYFDGHATQAYDGRETAPAAATERLFYGPTGQPMRFYEGVVGGRSVGTPGVLRMLDAAHRAHGKLPWRRLFQPAIRLAEHGFTISPRLAMLIANDKYLMNDPAARAYFYNDDGTPKAAGTVLKNPALATVLRQVADRGANAFYSGAIARDIVSKVRKHPTNPGLLSLQDLARYKAKVRAPLCTDYRRSVVCGMPPPSSGGLAIAQMLGILEAMPDWQQIGAQKPVRNEVGYEPTPFATHLFSEAGRLAFADRARYVADPDFAPLPGGSWASLTDNSYLARRARLIGDNSMGVAQAGTPQGATLALADDRSPELPSTSDIAIVDRYGQALSMTTSVEDAFGSRLMVRGFMLNNQLTDFSFVSSENGLPVANRVQPGKRPRSAMSPELVFDQKTKQVTMIVGSAGGPAIINHVAKTLIGVLDWGMTMQQAIALPNVGSTNGPTQLERGRVSDALVDGLKGRGHDVQVVEMNSGLQGIQRLNVQGQTVWFGGADPRREGVAMGD
>NC_010551.1|WP_006753858.1|3104441_3105434_-|lipoyl-synthase
MTDVTASPAPADSAATAAYDPTAKQKAQAKTARIPIKVIPIEKLKKPEWIRVKAATGSSRFNEIKTILREHNLHTVCEEASCPNIGECFGKGTATFMIMGDKCTRRCPFCDVGHGRPDPLDADEPKNLARTIAALKLKYVVITSVDRDDLRDGGAGHFVECIREVREQSPETRIEILTPDFRGRLDRAISILNAAPPDVMNHNLETVPRLYKEARPGSDYAHSLKLLKDFKALHPDVATKSGLMVGLGETEEEILQVMRDLRAHDVDMLTIGQYLQPSEHHLPVRAYVHPDTFKMYEEEAYKMGFTHAAVGAMVRSSYHADLQAHGAGVV
>NC_010551.1|WP_012364793.1|3105426_3106182_-|lipoyl(octanoyl)-transferase-LipB
MSVSPVPIVSTPVAVSESPAGSPVQPAVPVTVRWRGSEAYETSFDAMRAFTDTRTADTGDEIWVVEHPPVYTLGQAGDPAHLLVADSGVPLVKVDRGGQITYHGPGQIVVYLLLDLRRRKLMVRTLVTKIEEAVIETLAAYNLASVRKAGAPGIYVASGVHEGAKIAALGLKIRNGCSYHGLSLNVKMDLRPFLAINPCGYAGLETVDMASLEVAADWNDVAHTLVGRLIANLDGESAAADKPQALEHSND
>NC_010551.1|WP_012364794.1|3106265_3106592_-|DUF2917-domain-containing-protein
MQEISSSITFEIPAGETVPMKVQRSTRLTVQCGPVWATRSNDVEDYFLVDGETLRLRRGERLWLSAESGQGAHVAFSVSRPAAEVARGMLARLRNRVNALLHDGWRTV
>NC_010551.1|WP_006753861.1|3106694_3107666_+|transcriptional-regulator-GcvA
MDLRQLPALNAIRAFEAAARHENFSRAADELFVTHGAVSHQVRALEEELGVQLFARNGKRLCLTGAGMRYAQQVRTALMMLADATREVRASDRDRRLVVSMLSSFAARFVTPRIGTFIERHPEIDVELQSTNNLTDFARDDVDLAIRFGFGNYPGLHVEPLFDEVFFPACAPTLNGGKLPQTPADLVHYNLLRSDDELWRPWFDAAGLDTLTEPKRGILYQDSSNLLLAAIEGQGIALVRRSLAVHDLLDGRLVRLFDIDGASPWHYFFVCPPPLLNAPRVQAFRAWMFEEVAQFKLLCDELDARRAAGKTPAECAQEGGWKG

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Crispr_ID: NC_010551_6

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_010551_6

3201282-3201388

Orphan

Consensus_repeat	Method
CTGAACGCGGGCAAGCGCTGACGCGG	CRISPRCasFinder

1 spacers

The CRISPR arrays of NC_010551_6

>merge|NC_010551|6|3201282-3201388|CRISPRCasFinder
CTGAACGCGGGCAAGCGCTGACGCGGAGGCGGCGCGGCTGGCCCCGGATGCCGCGGCGGGCACAGCGCGCAGCAAGGCACCCTGAACGCGGGCAGGCGCTGACGCGG

>NC_010551|6|6|3201282-3201388|CRISPRCasFinder
CTGAACGCGGGCAAGCGCTGACGCGG	AGGCGGCGCGGCTGGCCCCGGATGCCGCGGCGGGCACAGCGCGCAGCAAGGCACC
CTGAACGCGGGCAGGCGCTGACGCGG

Protein	Signature genes	Signature genes Name	Protein_function
NC_010551.1\|WP_006754117.1\|3203601_3204621_+\|LacI-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|224525
NC_010551.1\|WP_012364863.1\|3204617_3205898_+\|AGE-family-epimerase/isomerase	unknown	unknown	gnl\|CDD\|225493
NC_010551.1\|WP_006754262.1\|3192627_3192834_+\|DUF1289-domain-containing-protein	unknown	unknown	gnl\|CDD\|377738
NC_010551.1\|WP_012364866.1\|3207701_3208892_-\|class-I-SAM-dependent-methyltransferase	unknown	unknown	gnl\|CDD\|224481
NC_010551.1\|WP_011658097.1\|3195779_3196739_+\|nitronate-monooxygenase	unknown	unknown	gnl\|CDD\|224981
NC_010551.1\|WP_012364857.1\|3194603_3195500_-\|alpha/beta-hydrolase	unknown	unknown	gnl\|CDD\|223669
NC_010551.1\|WP_012364867.1\|3208905_3209649_+\|SDR-family-oxidoreductase	unknown	unknown	gnl\|CDD\|236389
NC_010551.1\|WP_012364859.1\|3197996_3199073_-\|porin	unknown	unknown	gnl\|CDD\|238208
NC_010551.1\|WP_011658094.1\|3192124_3192631_+\|YbaK/EbsC-family-protein	unknown	unknown	gnl\|CDD\|239825
NC_010551.1\|WP_012364868.1\|3210128_3211151_+\|tRNA-2-thiocytidine(32)-synthetase-TtcA	unknown	unknown	gnl\|CDD\|236737
NC_010551.1\|WP_011658106.1\|3206910_3207132_+\|hypothetical-protein	unknown	unknown	unknown
NC_010551.1\|WP_012364864.1\|3205894_3206803_+\|carbohydrate-kinase	unknown	unknown	gnl\|CDD\|238572
NC_010551.1\|WP_041489960.1\|3199440_3199926_-\|hypothetical-protein	unknown	unknown	unknown
NC_010551.1\|WP_011658110.1\|3209727_3210132_+\|dihydroneopterin-aldolase	unknown	unknown	gnl\|CDD\|214902
NC_010551.1\|WP_012364856.1\|3193063_3193966_-\|EamA-family-transporter	unknown	unknown	gnl\|CDD\|273359
NC_010551.1\|WP_012364855.1\|3191170_3192103_+\|hydroxymethylglutaryl-CoA-lyase	unknown	unknown	gnl\|CDD\|180206
NC_010551.1\|WP_012364862.1\|3201585_3203424_+\|phosphodiesterase	unknown	unknown	gnl\|CDD\|238923
NC_010551.1\|WP_006754260.1\|3194079_3194571_+\|Lrp/AsnC-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|224439
NC_010551.1\|WP_012364858.1\|3196862_3197825_-\|LysR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|176114
NC_010551.1\|WP_012364865.1\|3207209_3207404_-\|DUF2905-domain-containing-protein	unknown	unknown	gnl\|CDD\|378570

Protein	Function_ID	Function_description	E-value
NC_010551.1\|WP_006754117.1\|3203601_3204621_+\|LacI-family-transcriptional-regulator	gnl\|CDD\|224525	COG1609, PurR, Transcriptional regulators [Transcription].	4.12527e-78
NC_010551.1\|WP_012364863.1\|3204617_3205898_+\|AGE-family-epimerase/isomerase	gnl\|CDD\|225493	COG2942, COG2942, N-acyl-D-glucosamine 2-epimerase [Carbohydrate transport and metabolism].	2.94423e-109
NC_010551.1\|WP_006754262.1\|3192627_3192834_+\|DUF1289-domain-containing-protein	gnl\|CDD\|377738	pfam06945, DUF1289, Protein of unknown function (DUF1289). This family consists of a number of hypothetical bacterial proteins. The aligned region spans around 56 residues and contains 4 highly conserved cysteine residues towards the N-terminus. The function of this family is unknown. Structural modelling suggests this domain may bind nucleic acids.	9.16639e-16
NC_010551.1\|WP_012364866.1\|3207701_3208892_-\|class-I-SAM-dependent-methyltransferase	gnl\|CDD\|224481	COG1565, COG1565, Uncharacterized conserved protein [Function unknown].	6.77172e-117
NC_010551.1\|WP_011658097.1\|3195779_3196739_+\|nitronate-monooxygenase	gnl\|CDD\|224981	COG2070, COG2070, Dioxygenases related to 2-nitropropane dioxygenase [General function prediction only].	1.34575e-94
NC_010551.1\|WP_012364857.1\|3194603_3195500_-\|alpha/beta-hydrolase	gnl\|CDD\|223669	COG0596, MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [General function prediction only].	2.10659e-23
NC_010551.1\|WP_012364859.1\|3197996_3199073_-\|porin	gnl\|CDD\|238208	cd00342, gram_neg_porins, Porins form aqueous channels for the diffusion of small hydrophillic molecules across the outer membrane. Individual 16-strand anti-parallel beta-barrels form a central pore, and trimerizes thru mainly hydrophobic interactions at the interface. Trimers are stabilized by hytrophillic clamping of Loop L2. Loop 3 bends into the pore, creating an elliptical constriction of about 7 x 11A, large enough to allow passage of a glucose molecule without steric hindrance. Removal of the C-terminal residue (usuallly F) destabilizes the trimer and removal of the 16th beta-sheet abolishes trimerization. Unlike typical membrane proteins, porins lack long hydrophobic stretches. Short turns are found at the smooth, periplasmic end, longer irregular loops are found at the rough, extracellular end. C-terminal residue forms salt bridge with N-terminus.	9.90167e-64
NC_010551.1\|WP_011658094.1\|3192124_3192631_+\|YbaK/EbsC-family-protein	gnl\|CDD\|239825	cd04333, ProX_deacylase, This CD, composed mainly of bacterial single-domain proteins, includes the Thermus thermophilus (Tt) YbaK-like protein, a homolog of the trans-acting Escherichia coli YbaK Cys-tRNA(Pro) deacylase and the Agrobacterium tumefaciens ProX Ala-tRNA(Pro) deacylase and also the cis-acting prolyl-tRNA synthetase-editing domain (ProRS-INS). While ProX and ProRS-INS hydrolyze misacylated Ala-tRNA(Pro), the E. coli YbaK hydrolyzes misacylated Cys-tRNA(Pro). A few CD members are N-terminal, YbaK-ProX-like domains of an uncharacterized protein with a C-terminal, predicted Fe-S protein domain.	4.09956e-59
NC_010551.1\|WP_012364868.1\|3210128_3211151_+\|tRNA-2-thiocytidine(32)-synthetase-TtcA	gnl\|CDD\|236737	PRK10696, PRK10696, tRNA 2-thiocytidine biosynthesis protein TtcA; Provisional.	0
NC_010551.1\|WP_012364867.1\|3208905_3209649_+\|SDR-family-oxidoreductase	gnl\|CDD\|236389	PRK09134, PRK09134, SDR family oxidoreductase.	9.25936e-47
NC_010551.1\|WP_012364864.1\|3205894_3206803_+\|carbohydrate-kinase	gnl\|CDD\|238572	cd01167, bac_FRK, Fructokinases (FRKs) mainly from bacteria and plants are enzymes with high specificity for fructose, as are all FRKs, but they catalyzes the conversion of fructose to fructose-6-phosphate, which is an entry point into glycolysis via conversion into glucose-6-phosphate. This is in contrast to FRKs [or ketohexokinases (KHKs)] from mammalia and halophilic archaebacteria, which phosphorylate fructose to fructose-1-phosphate.	7.29392e-90
NC_010551.1\|WP_011658110.1\|3209727_3210132_+\|dihydroneopterin-aldolase	gnl\|CDD\|214902	smart00905, FolB, Dihydroneopterin aldolase. Dihydroneopterin aldolase catalyses the conversion of 7,8-dihydroneopterin to 6-hydroxymethyl-7,8-dihydropterin in the biosynthetic pathway of tetrahydrofolate. In the opportunistic pathogen Pneumocystis carinii, dihydroneopterin aldolase function is expressed as the N-terminal portion of the multifunctional folic acid synthesis protein (Fas). This region encompasses two domains, FasA and FasB, which are 27% amino acid identical. FasA and FasB also share significant amino acid sequence similarity with bacterial dihydroneopterin aldolases. This region consists of two tandem sequences each homologous to folB and which form tetramers.	1.77216e-27
NC_010551.1\|WP_012364856.1\|3193063_3193966_-\|EamA-family-transporter	gnl\|CDD\|273359	TIGR00950, Uncharacterized_inner_membrane_transporter_YicL, Carboxylate/Amino Acid/Amine Transporter. [Transport and binding proteins, Amino acids, peptides and amines].	1.55933e-15
NC_010551.1\|WP_012364855.1\|3191170_3192103_+\|hydroxymethylglutaryl-CoA-lyase	gnl\|CDD\|180206	PRK05692, PRK05692, hydroxymethylglutaryl-CoA lyase; Provisional.	0
NC_010551.1\|WP_012364862.1\|3201585_3203424_+\|phosphodiesterase	gnl\|CDD\|238923	cd01948, EAL, EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2). The EAL domain has been shown to stimulate degradation of a second messenger, cyclic di-GMP, and is a good candidate for a diguanylate phosphodiesterase function. Together with the GGDEF domain, EAL might be involved in regulating cell surface adhesiveness in bacteria.	1.7463e-59
NC_010551.1\|WP_006754260.1\|3194079_3194571_+\|Lrp/AsnC-family-transcriptional-regulator	gnl\|CDD\|224439	COG1522, Lrp, Transcriptional regulators [Transcription].	8.22481e-33
NC_010551.1\|WP_012364858.1\|3196862_3197825_-\|LysR-family-transcriptional-regulator	gnl\|CDD\|176114	cd08422, PBP2_CrgA_like, The C-terminal substrate binding domain of LysR-type transcriptional regulator CrgA and its related homologs, contains the type 2 periplasmic binding domain. This CD includes the substrate binding domain of LysR-type transcriptional regulator (LTTR) CrgA and its related homologs. The LTTRs are acting as both auto-repressors and activators of target promoters, controlling operons involved in a wide variety of cellular processes such as amino acid biosynthesis, CO2 fixation, antibiotic resistance, degradation of aromatic compounds, nodule formation of nitrogen-fixing bacteria, and synthesis of virulence factors, to name a few. In contrast to the tetrameric form of other LTTRs, CrgA from Neisseria meningitides assembles into an octameric ring, which can bind up to four 63-bp DNA oligonucleotides. Phylogenetic cluster analysis further showed that the CrgA-like regulators form a subclass of the LTTRs that function as octamers. The CrgA is an auto-repressor of its own gene and activates the expression of the mdaB gene which coding for an NADPH-quinone reductase and that its action is increased by MBL (alpha-methylene-gamma-butyrolactone), an inducer of NADPH-quinone oxidoreductase. The structural topology of this substrate-binding domain is most similar to that of the type 2 periplasmic binding proteins (PBP2), which are responsible for the uptake of a variety of substrates such as phosphate, sulfate, polysaccharides, lysine/arginine/ornithine, and histidine. The PBP2 bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap. After binding their specific ligand with high affinity, they can interact with a cognate membrane transport complex comprised of two integral membrane domains and two cytoplasmically located ATPase domains. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis.	1.52859e-76
NC_010551.1\|WP_012364865.1\|3207209_3207404_-\|DUF2905-domain-containing-protein	gnl\|CDD\|378570	pfam11146, DUF2905, Protein of unknown function (DUF2905). This is a family of bacterial proteins conserved of unknown function.	3.10404e-12

>NC_010551.1|WP_041489960.1|3199440_3199926_-|hypothetical-protein
MTERVKLKVGRWVAGVLGTLLMPFALAQPPHGGHAFGGHGFGGGDMRAYGQSAASAQVWRRALPPGGARAGGVSGYGSRWGLRPTPSYGHYAAQSPYRPISADSRQMPRPPGGGNVPMRAGSIRADVARYNEERGGRPMPPPRSQEEPAAHSPYFSPFYRN
>NC_010551.1|WP_012364859.1|3197996_3199073_-|porin
MKAFARRASRTSVKLIAAATCVAAAAPVHAQSSVSLYGQVDEWVGATKFPGGDRAWNVSGGGMSTSYWGLHGAEDLGNGYKAIFTLESFFRAQNGQFGRFQGDTFFARNAYVGVSSPYGTVTAGRLTTHLFLSTILFNPFYDSYTFSPMVYHVFLGLGTFPTYPSDQGAVGDSGWNNALSYTSPSFGGLNFGAMYALGNTAGDNRSKKWSAQFNYANGPFAATAVYQYVNFNNGPQDLSSLVTGMKSQGIGLVGATYDLKYVKLFGQYMYTKNDQVAGSWHVNTAQGGVSVPLGVGNAMASYAYSRDGGGLDQTRQTWAVGYDYPLSKRTDVYAAYMNDHISGLSSGNTFGAGIRAKF
>NC_010551.1|WP_012364858.1|3196862_3197825_-|LysR-family-transcriptional-regulator
MDTLVSMNVFRYVVEVGSFVGAAERMQMSAAMASKHVMHLEQQLGARLLHRTTRRVAPTEAGREYYERLVQALSELDEAGQAVGAASVVPQGRLRVTSLSAFGLRHVMQAVTDYAGRFPDVVVDMTLSDRVVDLIEEGYDVAVRAAPNGLKSSSLVARQIATAHILLVASPEYLEKHGTPQTIADLAHHNYLRRDSNSTMLDSLVIDAAAASRVNLNGNLIVNHLEGLRAAVLAGAGIALLGTEVVGDDIESGRLVPVLLDSVPPHEAPIYAVYASRRHVSAKVRSFVDFLAARFEGQSLCPSIESHLRVLPITRIKRAG
>NC_010551.1|WP_011658097.1|3195779_3196739_+|nitronate-monooxygenase
MALPAVLQNLTLPVIASPMFIVSYPELVLAQCKAGIVGSFPALNARPAELLDEWLTQIQSELADHKAKHPDAVIGPIAVNQIVHQSNVRLEHDVRVCVEHKVPIFITSLRAPAREIVDAVHSYGGIVLHDVINLRHAQKALEAGVDGLILVAAGAGGHAGTTSPFALVGEVRRMFDGPIVLSGSIANGGSILAAQAMGADFAYMGTRFIATQEAHAVEDYKHAILNAKSSDIIYTNLFTGVHGNYIRESIEKAGLDPDALPESDKTKMNFGGDKTKAWKDIWGAGQGVGLMDDLPSVGELVERMKREYDDAKARLGIAR
>NC_010551.1|WP_012364857.1|3194603_3195500_-|alpha/beta-hydrolase
MSFDAFASFRVTMQDTDIFGVKGGAGPPLLLLHGHPQTHMIWHRVAATLANHFTVIATDLRGYGASGRPPSDARHAPYSKRAMAADQVAVMRHFGFEQFHVCAHDRGARVAHRLALDHPAAVERMMLLDIAPTLAMYEKTDRAFATAYFHWFFLIQPAPLPETLIEGRTDAYIERVMGNRSAGLAPFAPEALAAYRAALAQPGAVHAMCEDYRASATIDLEHDRADLERGNKVACPLRVLWGERGIVGRCFDPLDEWRRVARDVSGRALDCGHYIPEEAPVALVDELLAFFDARDAAA
>NC_010551.1|WP_006754260.1|3194079_3194571_+|Lrp/AsnC-family-transcriptional-regulator
MSKRLSPPAVASLDATDRAILAALAEDARIATSELARQIGLSAPATADRVRRLEAQGVIAGFTVELDPRALGYTLQAIVRVKPLPGQLHLVEEVLRRIPEFVECDKVTGEDCFICRLYLRTIGHLDDILSKVTERAETSTAIVKSTPVPRRLPPLVEDDAARR
>NC_010551.1|WP_012364856.1|3193063_3193966_-|EamA-family-transporter
MASNETRRGAAEMVAAMMMSGTIGWLVMSSQQPLTNVVFFRCLFGAATLAIVCAALGFLRRALFSPRMLALATLGSVAIVANWLLLFAAYSRASISMATAVYNTQPFMLVALGAIVFRERINASTITWLALAFVGLVCVVRVEPAVLAVPGEYLEGVALSLGAAFLYAVSSIVTKHLKGTPPHLLALLQAGLGIVLLAPFAHFGTLPATPAQWLDLVVLGVVNTGVMYVLLYGAIQKLPVAMTGALSFVYPVVAIIVDRVAFGQTLAWTQVLGALLILLAAAGVNLGWRIVPARRASVGN
>NC_010551.1|WP_006754262.1|3192627_3192834_+|DUF1289-domain-containing-protein
MSDVPVVVGTVASPCTDVCRIDPRTDWCAGCLRTRDEIKGWRASDDDARRALLARLDARRRLLARSGA
>NC_010551.1|WP_011658094.1|3192124_3192631_+|YbaK/EbsC-family-protein
MTTPTSFDSLPDSARRVALLLRERGHSKGIVMLAETGKTSAEAAAGLGCSVAQIAKSILFRRESDGLPVLVVASGVNRVDEKKVAAQVGPVGRADAKFVRDHTGYAIGGVCPIGHLVEPVTLIDADLLALDSLWAAAGHPHAVFNLSPQELVSLTGAPVADVALRNDA
>NC_010551.1|WP_012364855.1|3191170_3192103_+|hydroxymethylglutaryl-CoA-lyase
MTFPTAVKIVEVGPRDGLQNEKTFVPTDVKIALVDRLSRAGFRNIEAASFVSPKWVPQMADGADVMAGIERRAGTVYSVLTPNLKGFENALAARADEVVIFGAASEAFSQRNINCSIAESIARFEPIAKAAKDAGVRLRGSVSCTLGCPYQGEVPVASVVDVVERFAALGCDEIDIADTIGVGTPKRTREVLSAVTRVFPRERLSGHFHDTYGQALANIYAALFEGIEIFHASVAGLGGCPYAKGATGNVATEDVLYLMQGLGIDTGIDLAQVVAAGDFISNAIGRANVSRAGRALLAKAQSATDAPSCV
>NC_010551.1|WP_012364862.1|3201585_3203424_+|phosphodiesterase
MPAPHPDSSVAPTTRLIAERALAAVFQPIVDLGSGTVVGYEGLIRGPRGTDLEPPAALFAQAARDGTTIALEQAAALACLDAFAALGCDGKLFLNFSAGTIVQLVRERERARQLLGRAGVGAERIVIELTEQTAMPDVARIEPAVASLRDAGIQFALDDYGTANASMNLWLRLHPDVVKIDRFFIHDIARDPLKFEAVRAMQHFAHASGAQLIAEGIENASDLIVVRDMGICCVQGFLLGRPNARPSPVVAPAARDAIRTPHIAVFPGAMRTARPAGTIAAKMLVPAPALPRDATSNDVLDLFNRMPGLHAVALVERGRPVALVNRRGFIDRFTLPYHREVFGKKPCLQFANDAPLMIDNATSVEQLAMLLASHDQRYLADGFVITEHGRYLGLGTGESLVRAVTEMRIEAARYANPLTFLPGNIPISAHIDRLLERDAGFHACYVDLNQFKPFNDQYGYWQGDEVLKFAATVLAGVCDPQRDFLGHVGGDDFLVLFQRDDWRARATDAIARFNDGAQRFYTQADRLAGGLRGEDRHGNPAFFGFVTMAIGAVGVPAGAHGAMRYGSDEIASVAALAKRRAKQQPGGLAVVDLDAGRAALRERGEPPLAAAG
>NC_010551.1|WP_006754117.1|3203601_3204621_+|LacI-family-transcriptional-regulator
MGTTIRDVARAAEVSIGTVSRALKNQPGLSEATRARIVEIAQRLGYDPAQLRPRIRRLTFLLHRQHNRFPASPFFSHVLHGVEDACRERGIVPTLLTVGPNDDVLRQMRPHAPDAIAVAGFIEPETIEALAATGRPLVLIDLWAPGLRSVNIDNATGAALAMRHLLATGRSRIAFIGGSAAHYSIAQRAIGYRRAFFEAGRLFDPAYEVTIDAGLDPDTGAARAMQQLLDAPGPRPDAVFAYNDAAALAAQRVCIARGVRIPEDIAIVGFDDIPAAAHANPPLTTLAVDKEALGRRGVELLLAEAPERTEISLPVELIVRASSQPAGSPALDTATVTES
>NC_010551.1|WP_012364863.1|3204617_3205898_+|AGE-family-epimerase/isomerase
MNMPPVQSRTATPANHAQAAPFVASFRDPSFLLSHIEDTLRFYATNAFDPTGGFYHYFRDDGSVYNRTSRHLVSSCRFVFNYAMAYRHFGDPRHLEYARHGLRFLRDAHWDDELQGYDWELDWRDGAKRETLDATRHCYGLAFVLLAAAHATMAGIDEARALIASTFELAEHRFWDAAAGLYADDATPNWHVSSYRGQNANMHMTEALLAAYEATGHVTYLDRAEKLATHVTQRQAALSGGLVWEHYHADWSVDWDYNKEDSSNIFRPWGFQPGHQTEWAKLLLILERHRPLDWLVPRAAELFDAALTHAWDADHGGLCYGFGPDFTICDHNKYFWVQAETFAAAAMLGARTGSERFWDWYDEIWRYSWAHFVDHRYGAWYRILTCDNRKYSDEKSPAGKTDYHTMGACYDVLATLARAARSEPTQ
>NC_010551.1|WP_012364864.1|3205894_3206803_+|carbohydrate-kinase
MSGGTFPAFVSAGDILTDMVRAGDAQWTSVPGGAGWNVARAVARLGMPSALAGAIGEDCFSDVLWRTSDAAGLDLRFLQRVPRAPLLAIVHETRPPAYFFIGDASADLAFDPARLPAGWTEHVQWAHFGCISLVREPLASTLVALAADLHARGVKISFDPNYRNLMTAAYRPTLEKMAGLADLIKVSDEDLRHLFGGDGPDAVDAVRALNPRAAVLVTRGAQAATLYADGDVLEASPPRVEVVDTVGAGDASIGGLLFSLMAAPQRPWREHLAFALAAGAAACRHTGAHAPTLDEVVALLER
>NC_010551.1|WP_011658106.1|3206910_3207132_+|hypothetical-protein
MDTNTFTKGIYTAKAHTQHTANGQYQGYVILARDDGDETENMRYDVHTTSPSEEEAFDEAKALAHRILGEIEL
>NC_010551.1|WP_012364865.1|3207209_3207404_-|DUF2905-domain-containing-protein
MLRWLMASFFAVMILTRCWPWLGKLGVGRMPGDVTLTLGGRRYPFPFMSTLVVTMLVSMVARLL
>NC_010551.1|WP_012364866.1|3207701_3208892_-|class-I-SAM-dependent-methyltransferase
MNPKAHESASLPAPGPDALAQSEMLAAQLRDEIAAAGGWLPFDRFMERALYAPGLGYYSGGARKFGRRADDGSDFVTAPELSPLFAQTLANPVADALAASGTRRVMEFGAGTGKLAAGLLAAFDALDVELDEYLIVDLSGELRERQRDTIAASAPALAGKVRWLDALPERFDGVVVGNEVLDAMPVRLFAKSGGAWLERGVTLDARHAFVFGDRPVGAAGLPPVLATLDVDDGYVTETHEAALAFTRTVCTMLARGAVLLVDYGFPAHEYYHPQRDRGTLMCHYRHHAHDDAFLYPGLQDITAHVEFTGIYDAGVGTGADLLGYTSQARFLLNAGITDALAAIDPSDIHQFLPAANAVQKLISEAEMGELFKVIAFSRGIDGTLDAFARGDRSHAL
>NC_010551.1|WP_012364867.1|3208905_3209649_+|SDR-family-oxidoreductase
MTVSADTSTPRIALVAGALDSAADAASLGRALATAFAQRGWDVALQRSAGAPRAAGDALVAEVAARGRRAAVLDADLALEADAGALVAACGAALGRPTCAVFVSACAGTDDAQTVDAAALAGALARNVTAPLALARALADATPDAARDDETLRACVIHVLDQALFHPAPARLSHALMQAALNRATAALALALAPKVRVAALVRGHAPHADDIAAAACYLASAPGVTGATLTVDGGEHLVPPAAGPNE
>NC_010551.1|WP_011658110.1|3209727_3210132_+|dihydroneopterin-aldolase
MFSALLHPRLADCRRLYLRDYEVHMKIGAFEHEKRGEQRVVINIDLFVPLALSTPVDDRLHEVVDYDLMKQSVAQCLARGHIHLQETLCDAIAANLLAHDIVRAVRVRTEKPDAYPDCDAVGVEVFRIKDEERA
>NC_010551.1|WP_012364868.1|3210128_3211151_+|tRNA-2-thiocytidine(32)-synthetase-TtcA
MNAPHMHDTAADGAAIEATVADIADTGRRALTRREQKEAYENNKLFKRIVRQVGQAIGDYNMIEQGDKVMVCLSGGKDSYAMLDVLLRLRERAPIDFDIVAVNLDQKQPGFPEHVLPEYLTQIGVPFHIENQDTYSIVKRLVPEGKTTCSLCSRLRRGILYRVAGELGATKIALGHHRDDILQTLLLNMFYGGKLKGMPPKLQSDDGKNVVIRPLAYVKETDLEKFAELREFPIIPCNLCGSQPNLKRAEMKALIRDWDKRFPGRVDNMFSALANVVPSHLMDTTQFPFASLRATGQADPQGDIAFDEEPCASGDDTAATRDGARPIAARPISIVQFDDL

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NC_010551_5	5.1\|3095094\|26\|NC_010551\|CRISPRCasFinder	3095094-3095119	26	NZ_CP020399	Burkholderia multivorans strain FDAARGOS_246 plasmid unnamed, complete sequence	448865-448890	2	0.923
NC_010551_5	5.1\|3095094\|26\|NC_010551\|CRISPRCasFinder	3095094-3095119	26	NZ_CP012748	Paraburkholderia caribensis MBA4 plasmid unnamed, complete sequence	445484-445509	4	0.846
NC_010551_5	5.1\|3095094\|26\|NC_010551\|CRISPRCasFinder	3095094-3095119	26	NZ_CP012748	Paraburkholderia caribensis MBA4 plasmid unnamed, complete sequence	445533-445558	4	0.846
NC_010551_5	5.1\|3095094\|26\|NC_010551\|CRISPRCasFinder	3095094-3095119	26	NZ_CP012748	Paraburkholderia caribensis MBA4 plasmid unnamed, complete sequence	445582-445607	4	0.846
NC_010551_5	5.1\|3095094\|26\|NC_010551\|CRISPRCasFinder	3095094-3095119	26	NC_047925	Lactobacillus phage Nyseid, complete genome	76513-76538	6	0.769
NC_010551_5	5.1\|3095094\|26\|NC_010551\|CRISPRCasFinder	3095094-3095119	26	KU052488	Lactobacillus phage SA-C12, complete genome	32574-32599	6	0.769
NC_010551_5	5.1\|3095094\|26\|NC_010551\|CRISPRCasFinder	3095094-3095119	26	NC_047897	Lactobacillus phage Lenus, complete genome	73873-73898	6	0.769
NC_010551_5	5.1\|3095094\|26\|NC_010551\|CRISPRCasFinder	3095094-3095119	26	MT162468	Synechococcus phage S-H25, complete genome	16021-16046	6	0.769

1. spacer 5.1|3095094|26|NC_010551|CRISPRCasFinder matches to NZ_CP020399 (Burkholderia multivorans strain FDAARGOS_246 plasmid unnamed, complete sequence) position: , mismatch: 2, identity: 0.923

agagttagtgctttagcacttacccg	CRISPR spacer
agcgttagtgctttagcacttacacg	Protospacer
** ******************** **

2. spacer 5.1|3095094|26|NC_010551|CRISPRCasFinder matches to NZ_CP012748 (Paraburkholderia caribensis MBA4 plasmid unnamed, complete sequence) position: , mismatch: 4, identity: 0.846

agagttagtgctttagcacttacccg	CRISPR spacer
agagttagcgctttagcgcttactca	Protospacer
********.********.*****.*.

3. spacer 5.1|3095094|26|NC_010551|CRISPRCasFinder matches to NZ_CP012748 (Paraburkholderia caribensis MBA4 plasmid unnamed, complete sequence) position: , mismatch: 4, identity: 0.846

agagttagtgctttagcacttacccg	CRISPR spacer
agagttagcgctttagcgcttactca	Protospacer
********.********.*****.*.

4. spacer 5.1|3095094|26|NC_010551|CRISPRCasFinder matches to NZ_CP012748 (Paraburkholderia caribensis MBA4 plasmid unnamed, complete sequence) position: , mismatch: 4, identity: 0.846

agagttagtgctttagcacttacccg	CRISPR spacer
agagttagcgctttagcgcttactct	Protospacer
********.********.*****.*

5. spacer 5.1|3095094|26|NC_010551|CRISPRCasFinder matches to NC_047925 (Lactobacillus phage Nyseid, complete genome) position: , mismatch: 6, identity: 0.769

agagttagtgctttagcacttacccg	CRISPR spacer
tcagttagtgctttagcacttatata	Protospacer
  ********************. ..

6. spacer 5.1|3095094|26|NC_010551|CRISPRCasFinder matches to KU052488 (Lactobacillus phage SA-C12, complete genome) position: , mismatch: 6, identity: 0.769

agagttagtgctttagcacttacccg	CRISPR spacer
tcagttagtgctttagcacttatata	Protospacer
  ********************. ..

7. spacer 5.1|3095094|26|NC_010551|CRISPRCasFinder matches to NC_047897 (Lactobacillus phage Lenus, complete genome) position: , mismatch: 6, identity: 0.769

agagttagtgctttagcacttacccg	CRISPR spacer
tcagttagtgctttagcacttatata	Protospacer
  ********************. ..

8. spacer 5.1|3095094|26|NC_010551|CRISPRCasFinder matches to MT162468 (Synechococcus phage S-H25, complete genome) position: , mismatch: 6, identity: 0.769

agagttagtgctttagcacttacccg	CRISPR spacer
gcagttagtgcttttgcacttacaat	Protospacer
. ************ ********

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

411014 : 456572

uncultured_Caudovirales_phage(40.0%)

transposase,protease,plate

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_012362941.1\|411014_411536_+\|protease	ClpXP protease specificity-enhancing factor	A0A1S5R3H3	Pseudomonas_phage	3.7e-20	48.7
WP_041489745.1\|412214_412502_+	hypothetical protein	NA	NA	NA	NA
WP_012362944.1\|413700_415407_+	ShlB/FhaC/HecB family hemolysin secretion/activation protein	NA	NA	NA	NA
WP_012362945.1\|415486_416389_+	hypothetical protein	NA	NA	NA	NA
WP_012362946.1\|416584_425971_+	filamentous hemagglutinin N-terminal domain-containing protein	A0A0R6PJK4	Moraxella_phage	9.8e-31	32.7
WP_012362947.1\|426298_426823_+	hypothetical protein	NA	NA	NA	NA
WP_041489893.1\|428439_428697_+\|transposase	transposase	A0A218MNI5	uncultured_virus	6.4e-10	30.4
WP_006757125.1\|428961_429165_+	hypothetical protein	NA	NA	NA	NA
WP_006751250.1\|429247_430048_-	cystine ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_012362948.1\|430360_433534_+	type VI secretion system tip protein VgrG	A0A2H4JCD4	uncultured_Caudovirales_phage	1.7e-56	28.4
WP_012362950.1\|438244_438649_+	hypothetical protein	NA	NA	NA	NA
WP_041489746.1\|438756_439923_+	RHS repeat protein	A0A2H4JFP5	uncultured_Caudovirales_phage	5.0e-17	43.6
WP_041489747.1\|440581_440941_+	hypothetical protein	NA	NA	NA	NA
WP_041489748.1\|440974_441319_-	hypothetical protein	NA	NA	NA	NA
WP_012362953.1\|442311_442695_+	DUF2750 domain-containing protein	NA	NA	NA	NA
WP_041489749.1\|443249_443510_+	hypothetical protein	NA	NA	NA	NA
WP_012362955.1\|443690_444116_+	SMI1/KNR4 family protein	NA	NA	NA	NA
WP_012362956.1\|444236_444488_+	hypothetical protein	NA	NA	NA	NA
WP_012362957.1\|444481_444817_+	hypothetical protein	NA	NA	NA	NA
WP_012362958.1\|445209_445518_+	hypothetical protein	NA	NA	NA	NA
WP_012362959.1\|445534_445789_+	hypothetical protein	NA	NA	NA	NA
WP_041489751.1\|446160_446460_+	hypothetical protein	NA	NA	NA	NA
WP_006751242.1\|446553_447336_-	DotU family type IV/VI secretion system protein	NA	NA	NA	NA
WP_012362961.1\|447332_448679_-\|plate	type VI secretion system baseplate subunit TssK	NA	NA	NA	NA
WP_012362962.1\|448783_449392_-	type VI secretion system lipoprotein TssJ	NA	NA	NA	NA
WP_011655822.1\|449768_450407_+	tetratricopeptide repeat protein	NA	NA	NA	NA
WP_006751238.1\|450451_450967_+	type VI secretion system contractile sheath small subunit	NA	NA	NA	NA
WP_006751237.1\|450982_452473_+	type VI secretion system contractile sheath large subunit	NA	NA	NA	NA
WP_006477093.1\|452543_453047_+	type VI secretion system tube protein Hcp	NA	NA	NA	NA
WP_012362963.1\|453109_453595_+\|plate	type VI secretion system baseplate subunit TssE	NA	NA	NA	NA
WP_012362964.1\|453672_455508_+\|plate	type VI secretion system baseplate subunit TssF	NA	NA	NA	NA
WP_012362965.1\|455471_456572_+\|plate	type VI secretion system baseplate subunit TssG	NA	NA	NA	NA

DBSCAN-SWA_2

846952 : 854133

Enterobacteria_phage(33.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_012363223.1\|846952_848014_+	dTDP-glucose 4,6-dehydratase	I7HTA3	Enterobacteria_phage	1.7e-85	47.1
WP_006751098.1\|848025_848919_+	glucose-1-phosphate thymidylyltransferase RfbA	A0A291LA53	Escherichia_phage	9.8e-98	59.2
WP_012363224.1\|848903_849455_+	dTDP-4-dehydrorhamnose 3,5-epimerase	I7HJC4	Enterobacteria_phage	1.8e-49	53.0
WP_012363225.1\|849447_850347_+	dTDP-4-dehydrorhamnose reductase	A0A291LA50	Escherichia_phage	2.5e-24	34.7
WP_012363226.1\|850670_852119_+	mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase	A0A1V0SH58	Hokovirus	7.5e-55	28.8
WP_012363227.1\|852118_852913_+	ABC transporter permease	NA	NA	NA	NA
WP_012363228.1\|852912_854133_+	ABC transporter ATP-binding protein	A0A2H4PQG7	Staphylococcus_phage	4.1e-14	27.0

DBSCAN-SWA_3

3321962 : 3356153

Erwinia_phage(33.33%)

protease,plate

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_006760749.1\|3321962_3322499_+\|protease	ATP-dependent protease subunit HslV	NA	NA	NA	NA
WP_012364950.1\|3322509_3323853_+\|protease	ATP-dependent protease ATPase subunit HslU	A0A191ZC11	Erwinia_phage	7.9e-43	29.7
WP_011658200.1\|3324021_3324564_-	response regulator transcription factor	NA	NA	NA	NA
WP_012364951.1\|3324577_3325984_-	HAMP domain-containing histidine kinase	NA	NA	NA	NA
WP_041489871.1\|3326135_3326357_+	hypothetical protein	NA	NA	NA	NA
WP_006754950.1\|3326637_3327537_+	acetylglutamate kinase	NA	NA	NA	NA
WP_012364953.1\|3327533_3328325_+	pyrimidine 5'-nucleotidase	NA	NA	NA	NA
WP_012364954.1\|3328291_3328957_+	nucleoid occlusion factor SlmA	NA	NA	NA	NA
WP_012364955.1\|3329036_3331700_-	type VI secretion system ATPase TssH	A0A1C3S747	Escherichia_phage	3.9e-57	43.9
WP_050772537.1\|3332308_3333238_+	TagK domain-containing protein	NA	NA	NA	NA
WP_041489872.1\|3333218_3334079_+	ImpE protein	NA	NA	NA	NA
WP_012364958.1\|3334062_3334584_+\|plate	type VI secretion system baseplate subunit TssE	NA	NA	NA	NA
WP_012364959.1\|3334585_3336466_+\|plate	type VI secretion system baseplate subunit TssF	NA	NA	NA	NA
WP_012364960.1\|3336469_3337531_+\|plate	type VI secretion system baseplate subunit TssG	NA	NA	NA	NA
WP_012364961.1\|3337527_3338586_+	type VI secretion protein ImpA	NA	NA	NA	NA
WP_012364962.1\|3338627_3339659_+	fimbrial protein	NA	NA	NA	NA
WP_012364963.1\|3339698_3341054_+	hypothetical protein	A0A292GJ55	Xanthomonas_phage	3.5e-107	46.7
WP_012364964.1\|3341167_3344617_-	RHS repeat protein	NA	NA	NA	NA
WP_041489873.1\|3348241_3348805_-	hypothetical protein	NA	NA	NA	NA
WP_012364968.1\|3348785_3349571_-	DUF2094 domain-containing protein	NA	NA	NA	NA
WP_012364969.1\|3349579_3353488_-	type VI secretion system membrane subunit TssM	NA	NA	NA	NA
WP_012364970.1\|3353502_3354807_-	type VI secretion system protein TssL	NA	NA	NA	NA
WP_012364971.1\|3354803_3356153_-\|plate	type VI secretion system baseplate subunit TssK	NA	NA	NA	NA

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. NC_010557

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Click the colored protein region to show detailed information

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection

2. NC_010553

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection

3. NC_010551

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection