CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Target MGE spacer number	Prophage number
NC_010715	Natranaerobius thermophilus JW/NM-WN-LF plasmid pNTHE01, complete sequence	0 crisprs	NA	0	0
NC_010724	Natranaerobius thermophilus JW/NM-WN-LF plasmid pNTHE02, complete sequence	0 crisprs	NA	0	0
NC_010718	Natranaerobius thermophilus JW/NM-WN-LF, complete sequence	1 crisprs	RT,TnsE_C,DEDDh,csa3,WYL,DinG,PD-DExK,cas3,cas14j	1	8

Results visualization

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CRISPR-Cas detection and classification

Crispr_ID: NC_010718_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_010718_1

1305920-1306134

Orphan

Consensus_repeat	Method
ATTTTAACCCAAAAAATTTGTTATTATATATGAAGGA	CRT

3 spacers

The CRISPR arrays of NC_010718_1

>merge|NC_010718|1|1305920-1306134|CRT
TATTTAATCCAAAAAATTTGTTATTACTAGTGAGGGATAATTTTCGTGGAAATCACTTCATTTTAACCCAAAAAATTTGTTATTATATATGAAGGGGAGAACAATTACGTCAAAATTACTTTATTTTAACTCTAAAATTTTGTTATTATATATGAAGCAAGGTGAGAAAAATCACTTCATTTTAACCCAAAAAATTTGTTATTATATATGAAGGA

>NC_010718|1|1|1305920-1306134|CRT
TATTTAATCCAAAAAATTTGTTATTACTAGTGAGGGA	TAATTTTCGTGGAAATCACTTC
ATTTTAACCCAAAAAATTTGTTATTATATATGAAGGG	GAGAACAATTACGTCAAAATTACTTT
ATTTTAACTCTAAAATTTTGTTATTATATATGAAGCA	AGGTGAGAAAAATCACTTC
ATTTTAACCCAAAAAATTTGTTATTATATATGAAGGA

Protein	Signature genes	Signature genes Name	Protein_function
NC_010718.1\|WP_012447693.1\|1308028_1308898_+\|DUF5309-domain-containing-protein	unknown	unknown	gnl\|CDD\|379950
NC_010718.1\|WP_012447691.1\|1306682_1307426_+\|hypothetical-protein	unknown	unknown	unknown
NC_010718.1\|WP_012447685.1\|1300831_1301749_+\|tyrosine-type-recombinase/integrase	unknown	unknown	gnl\|CDD\|274042
NC_010718.1\|WP_012447699.1\|1312144_1312288_+\|hypothetical-protein	unknown	unknown	unknown
NC_010718.1\|WP_012447682.1\|1298598_1299402_+\|SAM-dependent-methyltransferase	unknown	unknown	gnl\|CDD\|225317
NC_010718.1\|WP_012447697.1\|1310251_1310458_+\|hypothetical-protein	unknown	unknown	unknown
NC_010718.1\|WP_012447687.1\|1303928_1304273_+\|hypothetical-protein	unknown	unknown	unknown
NC_010718.1\|WP_012447683.1\|1299516_1299753_+\|TatA/E-family-twin-arginine-targeting-protein-translocase	unknown	unknown	gnl\|CDD\|237837
NC_010718.1\|WP_012447692.1\|1307540_1307996_+\|hypothetical-protein	unknown	unknown	unknown
NC_010718.1\|WP_148206822.1\|1309288_1309801_+\|hypothetical-protein	unknown	unknown	unknown
NC_010718.1\|WP_012447690.1\|1306262_1306667_+\|hypothetical-protein	unknown	unknown	unknown
NC_010718.1\|WP_012447689.1\|1305108_1305468_+\|hypothetical-protein	unknown	unknown	unknown
NC_010718.1\|WP_012447681.1\|1297797_1298511_-\|radical-SAM-protein	unknown	unknown	gnl\|CDD\|223803
NC_010718.1\|WP_012447698.1\|1310473_1311991_+\|hypothetical-protein	unknown	unknown	unknown
NC_010718.1\|WP_012447696.1\|1309797_1310130_+\|hypothetical-protein	unknown	unknown	unknown
NC_010718.1\|WP_012447684.1\|1299847_1300576_+\|twin-arginine-translocase-subunit-TatC	unknown	unknown	gnl\|CDD\|376413
NC_010718.1\|WP_012447686.1\|1301822_1303136_+\|phage-portal-protein	unknown	unknown	gnl\|CDD\|377466
NC_010718.1\|WP_012447680.1\|1297364_1297751_-\|YjbQ-family-protein	unknown	unknown	gnl\|CDD\|376651
NC_010718.1\|WP_012447688.1\|1304278_1305088_+\|hypothetical-protein	unknown	unknown	unknown
NC_010718.1\|WP_012447694.1\|1308987_1309167_+\|helix-turn-helix-transcriptional-regulator	unknown	unknown	gnl\|CDD\|238045

Protein	Function_ID	Function_description	E-value
NC_010718.1\|WP_012447693.1\|1308028_1308898_+\|DUF5309-domain-containing-protein	gnl\|CDD\|379950	pfam17236, DUF5309, Family of unknown function (DUF5309). This is a family of uncharacterized proteins found in viruses and bacteria.	8.78489e-92
NC_010718.1\|WP_012447681.1\|1297797_1298511_-\|radical-SAM-protein	gnl\|CDD\|223803	COG0731, COG0731, Fe-S oxidoreductases [Energy production and conversion].	2.07989e-60
NC_010718.1\|WP_012447685.1\|1300831_1301749_+\|tyrosine-type-recombinase/integrase	gnl\|CDD\|274042	TIGR02224, Tyrosine_recombinase_XerC, tyrosine recombinase XerC. The phage integrase family describes a number of recombinases with tyrosine active sites that transiently bind covalently to DNA. Many are associated with mobile DNA elements, including phage, transposons, and phase variation loci. This model represents XerC, one of two closely related chromosomal proteins along with XerD (TIGR02225). XerC and XerD are site-specific recombinases which help resolve chromosome dimers to monomers for cell division after DNA replication. In species with a large chromosome and homologs of XerC on other replicons, the chomosomal copy was preferred for building this model. This model does not detect all XerC, as some apparent XerC examples score in the gray zone between trusted (450) and noise (410) cutoffs, along with some XerD examples. XerC and XerD interact with cell division protein FtsK. [DNA metabolism, DNA replication, recombination, and repair].	6.60815e-35
NC_010718.1\|WP_012447682.1\|1298598_1299402_+\|SAM-dependent-methyltransferase	gnl\|CDD\|225317	COG2519, GCD14, tRNA(1-methyladenosine) methyltransferase and related methyltransferases [Translation, ribosomal structure and biogenesis].	7.21282e-68
NC_010718.1\|WP_012447683.1\|1299516_1299753_+\|TatA/E-family-twin-arginine-targeting-protein-translocase	gnl\|CDD\|237837	PRK14861, tatA, twin arginine translocase protein A; Provisional.	6.41838e-22
NC_010718.1\|WP_012447694.1\|1308987_1309167_+\|helix-turn-helix-transcriptional-regulator	gnl\|CDD\|238045	cd00093, HTH_XRE, Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators.	0.000138365
NC_010718.1\|WP_012447686.1\|1301822_1303136_+\|phage-portal-protein	gnl\|CDD\|377466	pfam05133, Phage_prot_Gp6, Phage portal protein, SPP1 Gp6-like. This protein forms a hole, or portal, that enables DNA passage during packaging and ejection. It also forms the junction between the phage head (capsid) and the tail proteins. During SPP1 morphogenesis, Gp6 participates in the procapsid assembly reaction. This family also includes the old Pfam family Phage_min_cap (PF05126).	5.3513e-47
NC_010718.1\|WP_012447680.1\|1297364_1297751_-\|YjbQ-family-protein	gnl\|CDD\|376651	pfam01894, UPF0047, Uncharacterized protein family UPF0047. This family has no known function. The alignment contains a conserved aspartate and histidine that may be functionally important.	1.42865e-49
NC_010718.1\|WP_012447684.1\|1299847_1300576_+\|twin-arginine-translocase-subunit-TatC	gnl\|CDD\|376413	pfam00902, TatC, Sec-independent protein translocase protein (TatC). The bacterial Tat system has a remarkable ability to transport folded proteins even enzyme complexes across the cytoplasmic membrane. It is structurally and mechanistically similar to the Delta pH-driven thylakoidal protein import pathway. A functional Tat system or Delta pH-dependent pathway requires three integral membrane proteins: TatA/Tha4, TatB/Hcf106 and TatC/cpTatC. The TatC protein is essential for the function of both pathways. It might be involved in twin-arginine signal peptide recognition, protein translocation and proton translocation. Sequence analysis predicts that TatC contains six transmembrane helices (TMHs), and experimental data confirmed that N- and C-termini of TatC or cpTatC are exposed to the cytoplasmic or stromal face of the membrane. The cytoplasmic N-terminus and the first cytoplasmic loop region of the Escherichia coli TatC protein are essential for protein export. At least two TatC molecules co-exist within each Tat translocon.	2.9524e-67

>NC_010718.1|WP_012447689.1|1305108_1305468_+|hypothetical-protein
MKENREKELKGEIDNLKEITQAIQEWKSADEQKTENVMDTLTSLSNEMAELRKDVNEVKINLPTYYVTKEQHSQDKQELTQQIRQVEYNYKKDMWKLAGLFLTGAGIMFALIQLFVTSI
>NC_010718.1|WP_012447688.1|1304278_1305088_+|hypothetical-protein
MIENDFKFLLNQIGKPVKIDDGEKTTRTKAIISTHQNNFYKRIISTLYPIESGNIIEFDNQKFMITEPTYPKVDFKYKAVIEPMFYQIAIFDHDTDLFFFTDAIIKSFDMGMEDTDQFIVPTDEFKVILQRNDATDLIVENDYFYLFDFKWVVMGIDKTTPGVIKLTVEQDEKQDVKLPSEDDTYILISGETSVHEDSTYQYQAIAYQGVEELDKEIKFSIANDVDSEITEDGELTVKDTVGTTIEIKAELEKDSDIYRILEVSVADLW
>NC_010718.1|WP_012447687.1|1303928_1304273_+|hypothetical-protein
MTNLERLKMEIKDIEVHEQELKVYLEENQLKPDEEYKTDSPINKRRIYQTALSILESLANSPTTMKRYTHEDMTVSQFAENLQNRIDQLERTIRQLSVSDSHNKKSSTFMLFKE
>NC_010718.1|WP_012447686.1|1301822_1303136_+|phage-portal-protein
MTTLQDYIEENYNDRETFFKEEVNRMDNVKRVNEIIDIKEFLEGKNHSILNSQTEEYKGKTYYPATIVLNYAKTICNFQTNFLLKNPVSLTCSNEGLLNRVKEVYDIGNYDRIDFDILDKVVKYGNAYEYPYISEDGYIYSKIIPPEDGYPIFSEFGNEYIGFIESYTVDNVTFWVVFTEDKVEEYSNKGGKIHKIGEYENVSGLPCIYKSDNELDENFGRSDVLRFGEIIEEMERLISRSCDGLYKYMDGLPIMSGQQLEGEEGVNPKIAGEGLNLEDGAEFYFANNEINERAFKEIYNTLKQALLDISQTPAVAFNQTDISNLSEVSIRMMYTLASMKGSLNEKFMREGFEQRFDRFKRLLDYKGENYEGWETLDAVFHPALPRNDNEVIDNLQKLDDMGAISLDTLLDKNPYVNDKNFEKKRLEESNDNGNSEE
>NC_010718.1|WP_012447685.1|1300831_1301749_+|tyrosine-type-recombinase/integrase
MLLKFAIQDFIEDREFKNLTQKTISGYSATLKEFQEFISEQEVVNANDVTQSHIKSYLLHCKKNKNNNPTSINHKLHNLKIFFNYLQDIEVISEKQNPAKKINYVKEDIKIEVFNDYQIKQMLDYYRRIKRREKGFYAYRNYTIIVFLLGTGSRLGELINLRWDDIDFINNTIVFYGKKREYSSIPMTEKLKKELMEYKTYCEQTFESLSEYVFTNRKNEKLTDNAVKCIFKRLKKVMNFKNVRVSCHTFRHTFAVNMIKNNCDIFTLQKMLRHKDLSMCRRYVNFGTALKEQNDKFNPLNEIDV
>NC_010718.1|WP_012447684.1|1299847_1300576_+|twin-arginine-translocase-subunit-TatC
MSEQRDKMSFTDHLGELRQRLIWIVLAFLIATGIAFYFSETLLDIITVPADNLHYISPAEAFLSQLKLAIIAGLVFSLPVTLYQLIAFVLPALEPGEKKYLFIFLPLALILFVLGVLFAYFVILPLAYRFFINFAREDLLPMITVRSYVSFALGLLLPFGLVFQLPLIVTILSNLELITPEFLRTNRKIAVLITFVIGSFLTPPDLISQGLLAGPLIILYESSIMVSKFIYRRKNKHTGQAA
>NC_010718.1|WP_012447683.1|1299516_1299753_+|TatA/E-family-twin-arginine-targeting-protein-translocase
MFGRIGLPEILLILAIALIIFGPKKLPELGKALGSSLREFKSATKELREEVNEVEEEVKENKSSDVKENEDNKTEKST
>NC_010718.1|WP_012447682.1|1298598_1299402_+|SAM-dependent-methyltransferase
MSTGLDSKRMITDGNKFKKVVDLKADSVQLPTGILTGEKLRQLSPGSEFYLNEKKYFIFECTLADFLEKKLERKTQIMYPKEISFMIYKLDISPGDSVGEAGTGSGAMTLSLSRTVGPQGSVYTYERRSDFSKLVNKNYSRGRKFDNVTFYNQSIEEGIFETDLDAFVLDVREPWEVLDKISHSLKPSGNLGVLVPTYNQISATLPELKDNSFFVTDIVELLLRRYKHNPERMRPEDTMIGHTGYLIIAKKLTGETKSLEEISECEE
>NC_010718.1|WP_012447681.1|1297797_1298511_-|radical-SAM-protein
MSFVYGPVKSRRLGLSLGVDITPDRICSFDCIYCEEACATKTLTITRSEYSPTETVINEIVTQANNHPRLDYITFSGSGEPTLHSELGKIITEIKSQTDNAVAVLTNSSLLYREDVRNDLQKSDLVVPSIDAITEKSFTDINRPHEEINSSLIVNGIKTFCQEYTGKIYLEILLVSEVNDSYEEIEKLANFVNDLNVTKIHLNTVSRATTEPDAQNIPYDKLKEIVNLFSKPVEIFN
>NC_010718.1|WP_012447680.1|1297364_1297751_-|YjbQ-family-protein
MEITVTTSKKIEFINITEEVKKALSQMELPQGNNKVHLFIPHTTAAITVNETADPDVCFDLENACQKIIPDISYQHLEGNSPAHFLSSLVGPDIMVPIRKNTLDLGRWQGIIFCEFDGPRRRKVKILY
>NC_010718.1|WP_012447690.1|1306262_1306667_+|hypothetical-protein
MSDYLKIKFAETDEEVSQEGEFDNAIIFKLKADEEEKDSERLYIEADEDYHLEDVVIKIEGDTAEKWALAPDDDGEEGEYKDWGESLDLGDIDAEDTKHFWVKAKAEENEDLGQYDDVLITVEGLAEETGGDLW
>NC_010718.1|WP_012447691.1|1306682_1307426_+|hypothetical-protein
MPEEFAVDLQTERILTDDDTDFFSINFQTGRELSNPEEFTVSLQSGSELVGKVKSKLQTGRELFSDFKVKLQTERLVDSLGTESFSVGLQAARNIYGTVIKKLQTLRNMEDETLKHEVFETAMLPLDYQASYIDFQNRKWFSMMYSDEMIEFYKGEKRNLGLEVERTIYKYTGFEIDSVDVEIRKLDNDHTLVDEGEGKIDGNKVWYLVDTTKEDFETDQSYYIYFKINIDNSDKVIIDRLEFEIIE
>NC_010718.1|WP_012447692.1|1307540_1307996_+|hypothetical-protein
MKFEWTDDLKQQFDEEQQKTVEKLVQSHEDKIRTEYSQKLNDMESKIQELEQYKPEEKSEEQKKIEEKENELWQKQVDLTLKENGLDGFEGLITAKDEEDLNNKVEQLNNVLKKKKVNNSYVPREHGSTDKYSQAKQEGNPKEMIKSLINK
>NC_010718.1|WP_012447693.1|1308028_1308898_+|DUF5309-domain-containing-protein
MFTHNNFLQYESIDMSGVLEVTNVPQTPITSLLMVRQVQAQAPQVHWVEVEIDESSAVTQGEGDDAPEHKTDNRELKENYLEIFGATAKVSNTAQYSTSETVNDLLAHEVELKTQSIRNRMENKFINGNKNFADGVYETDGILNLINSENQKTEDEFNENVFLDTLQKLYDANVHDNMIVFLRPEEKIKINQEFNNVVKYTDTLDRVAGFDAEQYISPFGIVRFALAPKLPANTMFVINPAYLEMPTLIPFTARPQNPSGSKQEVYLETQAGVKLLNSYAGSTLEISTA
>NC_010718.1|WP_012447694.1|1308987_1309167_+|helix-turn-helix-transcriptional-regulator
MVTQEERDKLFLERRKKRLTLDEVANYVGCHKSLISKFELGECGMSDEKVERYREIIAT
>NC_010718.1|WP_148206822.1|1309288_1309801_+|hypothetical-protein
MEGNYIPDEEKLDFAEPPPQFKDEELYYDIGASYYVILDKLDKEESYEEHFHTKEVVYEDFAKESNKIHEELLEEASRDELVEGDYTDFDYEVVSMYVQFLNRYESYVENNIKETDNHFETDDFIYGESENSMMLKHIIKTFNELYGLDDQLEIIDEDFDLYEELGVEIE
>NC_010718.1|WP_012447696.1|1309797_1310130_+|hypothetical-protein
MMKNGAIVSYIISIIFIGIGFHKIFIYENPDSVLENAVNAYVGGDAYNFIINANYATGYFTLAIFFAVLGMSFMMAYIFLEYNQREDIKSIRSKGLENNEDIKESNSVDE
>NC_010718.1|WP_012447697.1|1310251_1310458_+|hypothetical-protein
MNENLKVATWYVVRSQRLAGFLMLKGFVLKKLDISREDPSRNVFLFNNTKELRDTVELYKEFKDKIFR
>NC_010718.1|WP_012447698.1|1310473_1311991_+|hypothetical-protein
MYSPKLDEDIQQKLIDKIYDLYIYRTDKYLKQNPGKEFMTLTKGKTTKKPLLPFMIKAHLEQNYTIGTFAGKGKNNRTYTKFICFDVDLKEDDNLAKWFTYKVAETLREMGINEYYISHSGGKGYHIEVFFEDLIPVKLAYKFYLLVLRFTDLYSYSDKGKIEFRPTEKEGVKLPLGLNQKYYQTGGYCGFCSEFERLRMLDEQEEINYFLNIQKIKRKKISKIVKKYKNYFEESNKKIQENKKTGTIENEIEETGEVLEQYQELGIYNQTEDEIFSKAMDYYRNGLKRTGTRHNVCLLLAKFLRYNGLEKGEAEQELKNWMKRQDEKTYRTPLEDSLKDIEKIVNWVYENNKSLVPPKKDLSISFDEINTIVTNCPQKNQKLLMYALLVHSKRYATEGGVFYMTFKQMEETTGLGFRTVFRQINELEELKMIEVVERNGKNFEYDYSLQKPISKPNRYRIKMKNENQSEKIELKDNFQDCLLEFYSDKQLKDLLPRRQYQYFIS
>NC_010718.1|WP_012447699.1|1312144_1312288_+|hypothetical-protein
MNKKTQDILNLIDEFKEQEKGQKEKMFTELYKLEEQVDEITKKLLNQ

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NC_010718_1	1.2\|1306016\|26\|NC_010718\|CRT	1306016-1306041	26	NC_007103	Bacillus cereus E33L plasmid pE33L466, complete sequence	264432-264457	5	0.808
NC_010718_1	1.2\|1306016\|26\|NC_010718\|CRT	1306016-1306041	26	NZ_CP009967	Bacillus cereus E33L plasmid pBCO_1, complete sequence	57747-57772	5	0.808
NC_010718_1	1.2\|1306016\|26\|NC_010718\|CRT	1306016-1306041	26	AP014351	Uncultured Mediterranean phage uvMED isolate uvMED-GF-U-MedDCM-OCT-S39-C3, * SEQUENCING IN PROGRESS *	26083-26108	5	0.808
NC_010718_1	1.2\|1306016\|26\|NC_010718\|CRT	1306016-1306041	26	MN871480	UNVERIFIED: Pseudomonas phage PaSz-1_45_270k, complete genome	241343-241368	6	0.769
NC_010718_1	1.2\|1306016\|26\|NC_010718\|CRT	1306016-1306041	26	MT133560	Pseudomonas phage fnug, complete genome	41624-41649	6	0.769
NC_010718_1	1.2\|1306016\|26\|NC_010718\|CRT	1306016-1306041	26	MN871489	UNVERIFIED: Pseudomonas phage PaZh_1, complete genome	272601-272626	6	0.769
NC_010718_1	1.2\|1306016\|26\|NC_010718\|CRT	1306016-1306041	26	NC_042081	Pseudomonas phage SL2, complete genome	244245-244270	6	0.769
NC_010718_1	1.2\|1306016\|26\|NC_010718\|CRT	1306016-1306041	26	KU521356	Pseudomonas phage KTN4, complete genome	42356-42381	6	0.769
NC_010718_1	1.2\|1306016\|26\|NC_010718\|CRT	1306016-1306041	26	MW057919	Pseudomonas phage vB_PaeM_kmuB, complete genome	42506-42531	6	0.769
NC_010718_1	1.2\|1306016\|26\|NC_010718\|CRT	1306016-1306041	26	AP019418	Pseudomonas phage PA02 DNA, nearly complete genome	182291-182316	6	0.769
NC_010718_1	1.2\|1306016\|26\|NC_010718\|CRT	1306016-1306041	26	DI373487	KR 1020130142837-A/1: Bacteriophage of Pseudomonas aeruginosa and uses thereof	265453-265478	7	0.731
NC_010718_1	1.2\|1306016\|26\|NC_010718\|CRT	1306016-1306041	26	NC_042060	Pseudomonas phage PA7, partial genome	265453-265478	7	0.731
NC_010718_1	1.2\|1306016\|26\|NC_010718\|CRT	1306016-1306041	26	NC_004629	Pseudomonas phage phiKZ, complete genome	40741-40766	7	0.731

1. spacer 1.2|1306016|26|NC_010718|CRT matches to NC_007103 (Bacillus cereus E33L plasmid pE33L466, complete sequence) position: , mismatch: 5, identity: 0.808

gagaacaattacgtcaaaattacttt	CRISPR spacer
taaaacaattacgtcaaaattattca	Protospacer
 *.*******************.*.

2. spacer 1.2|1306016|26|NC_010718|CRT matches to NZ_CP009967 (Bacillus cereus E33L plasmid pBCO_1, complete sequence) position: , mismatch: 5, identity: 0.808

gagaacaattacgtcaaaattacttt	CRISPR spacer
taaaacaattacgtcaaaattattca	Protospacer
 *.*******************.*.

3. spacer 1.2|1306016|26|NC_010718|CRT matches to AP014351 (Uncultured Mediterranean phage uvMED isolate uvMED-GF-U-MedDCM-OCT-S39-C3, *** SEQUENCING IN PROGRESS ***) position: , mismatch: 5, identity: 0.808

gagaacaattacgtcaaaattacttt	CRISPR spacer
gcgaacaattacgtcaaaatttttca	Protospacer
* ******************* .*.

4. spacer 1.2|1306016|26|NC_010718|CRT matches to MN871480 (UNVERIFIED: Pseudomonas phage PaSz-1_45_270k, complete genome) position: , mismatch: 6, identity: 0.769

gagaacaattacgtcaaaattacttt	CRISPR spacer
aagaacaattacgtcaaaatggcgaa	Protospacer
.******************* .*

5. spacer 1.2|1306016|26|NC_010718|CRT matches to MT133560 (Pseudomonas phage fnug, complete genome) position: , mismatch: 6, identity: 0.769

gagaacaattacgtcaaaattacttt	CRISPR spacer
aagaacaattacgtcaaaatggcgaa	Protospacer
.******************* .*

6. spacer 1.2|1306016|26|NC_010718|CRT matches to MN871489 (UNVERIFIED: Pseudomonas phage PaZh_1, complete genome) position: , mismatch: 6, identity: 0.769

gagaacaattacgtcaaaattacttt	CRISPR spacer
aagaacaattacgtcaaaatggcgaa	Protospacer
.******************* .*

7. spacer 1.2|1306016|26|NC_010718|CRT matches to NC_042081 (Pseudomonas phage SL2, complete genome) position: , mismatch: 6, identity: 0.769

gagaacaattacgtcaaaattacttt	CRISPR spacer
aagaacaattacgtcaaaatggcgaa	Protospacer
.******************* .*

8. spacer 1.2|1306016|26|NC_010718|CRT matches to KU521356 (Pseudomonas phage KTN4, complete genome) position: , mismatch: 6, identity: 0.769

gagaacaattacgtcaaaattacttt	CRISPR spacer
aagaacaattacgtcaaaatggcgaa	Protospacer
.******************* .*

9. spacer 1.2|1306016|26|NC_010718|CRT matches to MW057919 (Pseudomonas phage vB_PaeM_kmuB, complete genome) position: , mismatch: 6, identity: 0.769

gagaacaattacgtcaaaattacttt	CRISPR spacer
aagaacaattacgtcaaaatggcgaa	Protospacer
.******************* .*

10. spacer 1.2|1306016|26|NC_010718|CRT matches to AP019418 (Pseudomonas phage PA02 DNA, nearly complete genome) position: , mismatch: 6, identity: 0.769

gagaacaattacgtcaaaattacttt	CRISPR spacer
aagaacaattacgtcaaaatggcgaa	Protospacer
.******************* .*

11. spacer 1.2|1306016|26|NC_010718|CRT matches to DI373487 (KR 1020130142837-A/1: Bacteriophage of Pseudomonas aeruginosa and uses thereof) position: , mismatch: 7, identity: 0.731

gagaacaattacgtcaaaattacttt	CRISPR spacer
aagaacaattacgtcaaaatggtgaa	Protospacer
.******************* ..

12. spacer 1.2|1306016|26|NC_010718|CRT matches to NC_042060 (Pseudomonas phage PA7, partial genome) position: , mismatch: 7, identity: 0.731

gagaacaattacgtcaaaattacttt	CRISPR spacer
aagaacaattacgtcaaaatggtgaa	Protospacer
.******************* ..

13. spacer 1.2|1306016|26|NC_010718|CRT matches to NC_004629 (Pseudomonas phage phiKZ, complete genome) position: , mismatch: 7, identity: 0.731

gagaacaattacgtcaaaattacttt	CRISPR spacer
aagaacaattacgtcaaaatggtgaa	Protospacer
.******************* ..

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

142231 : 152270

Staphylococcus_phage(37.5%)

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_012446609.1\|142231_143341_+	ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	8.9e-24	32.3
WP_012446610.1\|143327_144173_+	ABC transporter permease	G3M9Y4	Bacillus_virus	4.1e-05	25.4
WP_012446611.1\|144227_145169_+	glycine betaine ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_012446612.1\|145565_146708_+	bifunctional diaminohydroxyphosphoribosylaminopyrimidine deaminase/5-amino-6-(5-phosphoribosylamino)uracil reductase RibD	A0A1V0SE20	Indivirus	6.7e-51	34.9
WP_148206884.1\|146722_147424_+	riboflavin synthase	A0A2H4PQS5	Staphylococcus_phage	2.1e-34	40.3
WP_012446614.1\|147502_148741_+	bifunctional 3,4-dihydroxy-2-butanone-4-phosphate synthase/GTP cyclohydrolase II	A0A2H4PQS2	Staphylococcus_phage	4.3e-112	52.6
WP_012446615.1\|148733_149201_+	6,7-dimethyl-8-ribityllumazine synthase	A0A2H4PQS3	Staphylococcus_phage	1.3e-37	52.0
WP_012446616.1\|149391_149931_+	anaerobic ribonucleoside-triphosphate reductase activating protein	A0A0A8WJI9	Clostridium_phage	4.3e-24	41.0
WP_041367265.1\|150101_152270_+	anaerobic ribonucleoside-triphosphate reductase	A0A2R2ZH54	Clostridioides_phage	3.9e-148	40.7

DBSCAN-SWA_2

158783 : 166606

Bacillus_virus(28.57%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_012446624.1\|158783_159407_+	YigZ family protein	A0A1X9I5T8	Streptococcus_phage	2.8e-35	47.4
WP_012446625.1\|159518_160448_+	thioredoxin-disulfide reductase	G3MA85	Bacillus_virus	3.8e-76	49.2
WP_012446626.1\|160474_160798_+	thioredoxin	A0A1J0GW78	Streptomyces_phage	3.9e-20	43.7
WP_012446627.1\|160901_161681_+	Ku protein	A0A218M9C0	Mycobacterium_phage	1.9e-44	39.5
WP_012446628.1\|161684_162668_-	ATP-dependent DNA ligase	A0A068CDF3	Rhizobium_phage	2.9e-18	27.1
WP_158438186.1\|162810_163737_+	non-homologous end-joining DNA ligase	NA	NA	NA	NA
WP_012446630.1\|163777_163981_-	hypothetical protein	NA	NA	NA	NA
WP_012446631.1\|164020_164728_+	MgtC/SapB family protein	G3MA03	Bacillus_virus	4.6e-18	41.0
WP_012446632.1\|165178_166606_+	group II intron reverse transcriptase/maturase	A0A0U4J920	Pseudomonas_phage	1.8e-32	29.8

DBSCAN-SWA_3

476295 : 484344

Prochlorococcus_phage(33.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_012446935.1\|476295_477828_+	glutamine-hydrolyzing GMP synthase	A0A1V0SH76	Hokovirus	3.3e-21	32.4
WP_012446936.1\|478121_479285_+	5-(carboxyamino)imidazole ribonucleotide synthase	NA	NA	NA	NA
WP_012446937.1\|479274_479799_+	5-(carboxyamino)imidazole ribonucleotide mutase	A0A2P0VNU7	Tetraselmis_virus	3.9e-22	40.8
WP_012446938.1\|479798_481091_+	adenylosuccinate lyase	A0A1B3B081	Gordonia_phage	8.2e-21	35.3
WP_012446939.1\|481125_482208_+	phosphoribosylformylglycinamidine cyclo-ligase	Q58MH8	Prochlorococcus_phage	1.1e-63	41.3
WP_012446940.1\|482194_482818_+	phosphoribosylglycinamide formyltransferase	M4QRX9	Synechococcus_phage	1.3e-27	39.8
WP_041367319.1\|482829_484344_+	bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase	Q58MG4	Prochlorococcus_phage	1.7e-65	45.3

DBSCAN-SWA_4

739643 : 791749

Bacillus_phage(41.67%)

transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_148206803.1\|739643_740784_+\|transposase	IS3 family transposase	A0A1P8CWQ3	Bacillus_phage	1.3e-99	64.6
WP_012447191.1\|740988_741183_+	hypothetical protein	NA	NA	NA	NA
WP_041366882.1\|741167_742244_+	serpin family protein	A7XDC9	Tanapox_virus	2.8e-30	28.4
WP_012447193.1\|742372_742750_+	hypothetical protein	NA	NA	NA	NA
WP_012447194.1\|742790_743537_-	flavodoxin family protein	NA	NA	NA	NA
WP_012447195.1\|744122_745298_+	tryptophan synthase subunit beta	NA	NA	NA	NA
WP_083762678.1\|745292_745691_-	aldehyde dehydrogenase family protein	NA	NA	NA	NA
WP_052291943.1\|745698_745890_-	aldehyde dehydrogenase family protein	NA	NA	NA	NA
WP_052291944.1\|745932_746316_-	aldehyde dehydrogenase family protein	NA	NA	NA	NA
WP_052291945.1\|746270_746591_-	aldehyde dehydrogenase family protein	NA	NA	NA	NA
WP_052291946.1\|746590_746854_-	aldehyde dehydrogenase	NA	NA	NA	NA
WP_012447196.1\|747042_747222_+	hypothetical protein	NA	NA	NA	NA
WP_012447197.1\|747251_748787_-	serine hydrolase	A0A2P0ZZM8	Mycobacterium_phage	5.7e-05	26.9
WP_012447198.1\|749019_749505_+	hypothetical protein	NA	NA	NA	NA
WP_012447199.1\|749564_750344_+	glucose 1-dehydrogenase	L7RG25	Acanthamoeba_polyphaga_moumouvirus	5.7e-09	23.4
WP_012447200.1\|750389_751742_-	CapA family protein	NA	NA	NA	NA
WP_083762843.1\|751918_753517_+	FAD-dependent oxidoreductase	NA	NA	NA	NA
WP_012447202.1\|753659_756380_+	WG repeat-containing protein	NA	NA	NA	NA
WP_012447203.1\|756441_757476_+	hypothetical protein	NA	NA	NA	NA
WP_012447204.1\|757592_759587_-	ABC transporter permease	NA	NA	NA	NA
WP_012447205.1\|759561_760461_-	ABC transporter ATP-binding protein	A0A2H4PQG7	Staphylococcus_phage	2.3e-22	34.0
WP_012447206.1\|760453_760870_-	GntR family transcriptional regulator	NA	NA	NA	NA
WP_012447207.1\|761026_761554_-	superoxide dismutase family protein	NA	NA	NA	NA
WP_012447208.1\|761770_761950_-	hypothetical protein	NA	NA	NA	NA
WP_012447209.1\|762060_762603_-	peptide-methionine (S)-S-oxide reductase	NA	NA	NA	NA
WP_012447210.1\|763141_764545_+	Na+/H+ antiporter NhaC	NA	NA	NA	NA
WP_041366746.1\|764862_766182_-\|transposase	ISNCY family transposase	NA	NA	NA	NA
WP_012447211.1\|766393_766951_+	class I SAM-dependent methyltransferase	NA	NA	NA	NA
WP_012447212.1\|767098_769105_-	PBP1A family penicillin-binding protein	NA	NA	NA	NA
WP_012447213.1\|769313_769514_+	helix-turn-helix transcriptional regulator	A0A1V0E021	Clostridioides_phage	1.5e-06	46.7
WP_012447214.1\|769521_773043_+	PQQ-like beta-propeller repeat protein	NA	NA	NA	NA
WP_012447215.1\|773128_773398_-	TIGR03905 family TSCPD domain-containing protein	NA	NA	NA	NA
WP_012447216.1\|773732_774533_+	methyltransferase domain-containing protein	NA	NA	NA	NA
WP_041367378.1\|774577_774778_-	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_012447218.1\|774786_775098_-	DUF3796 domain-containing protein	NA	NA	NA	NA
WP_012447219.1\|775138_775753_-	hypothetical protein	NA	NA	NA	NA
WP_012447220.1\|775878_776577_-	response regulator transcription factor	Q6XM27	Feldmannia_irregularis_virus	2.0e-05	33.7
WP_012447221.1\|776573_777755_-	sensor histidine kinase	NA	NA	NA	NA
WP_012447222.1\|777926_778430_+	hypothetical protein	NA	NA	NA	NA
WP_012447223.1\|778798_779509_+	TetR/AcrR family transcriptional regulator	NA	NA	NA	NA
WP_012447224.1\|779608_782272_+	pyruvate, phosphate dikinase	A0A1V0SGR7	Hokovirus	7.3e-48	37.6
WP_158438209.1\|782487_782652_-	hypothetical protein	NA	NA	NA	NA
WP_012447225.1\|782743_782980_+	TM0996/MTH895 family glutaredoxin-like protein	NA	NA	NA	NA
WP_012447226.1\|783061_784231_+	permease	NA	NA	NA	NA
WP_012447227.1\|784349_784709_+	winged helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_012447228.1\|784928_785306_+	winged helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_012447229.1\|785326_786379_+	ACR3 family arsenite efflux transporter	NA	NA	NA	NA
WP_148206899.1\|786476_787397_-	DUF3231 family protein	NA	NA	NA	NA
WP_148206803.1\|787667_788808_+\|transposase	IS3 family transposase	A0A1P8CWQ3	Bacillus_phage	1.3e-99	64.6
WP_012447231.1\|788944_789502_+	hypothetical protein	NA	NA	NA	NA
WP_148206803.1\|789568_790710_-\|transposase	IS3 family transposase	A0A1P8CWQ3	Bacillus_phage	1.3e-99	64.6
WP_148206804.1\|790772_791498_-\|transposase	IS3 family transposase	A0A1P8CWQ3	Bacillus_phage	3.8e-76	64.2
WP_012447190.1\|791482_791749_-\|transposase	IS3 family transposase	A0A1P8CWP5	Bacillus_phage	9.5e-25	66.7

DBSCAN-SWA_5

1089864 : 1113544

Clostridium_phage(42.86%)

protease,transposase,integrase

attL 1083003:1083019|attR 1114714:1114730

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
1083003:1083019	attL	NA	NA	NA	NA
WP_148206815.1\|1089864_1090239_-\|transposase	IS200/IS605 family transposase	W0UUZ0	Sulfolobus_monocaudavirus	9.0e-29	51.7
WP_148206816.1\|1090351_1092292_-	FAD-dependent oxidoreductase	NA	NA	NA	NA
WP_012447484.1\|1092441_1093998_+	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_012447485.1\|1094088_1095363_-	anti sigma factor C-terminal domain-containing protein	NA	NA	NA	NA
WP_012447486.1\|1095352_1095859_-	RNA polymerase sigma factor	NA	NA	NA	NA
WP_012447487.1\|1096368_1097220_+\|integrase	tyrosine-type recombinase/integrase	S5W9T9	Leptospira_phage	1.6e-36	36.6
WP_012447488.1\|1097457_1097853_-	HEPN domain-containing protein	NA	NA	NA	NA
WP_012447489.1\|1097824_1098160_-	nucleotidyltransferase domain-containing protein	NA	NA	NA	NA
WP_041366924.1\|1098511_1098757_+	hypothetical protein	A0A0A8WF72	Clostridium_phage	1.0e-20	55.7
WP_012447491.1\|1098759_1099146_+\|protease	aspartyl protease family protein	A0A0A8WIU2	Clostridium_phage	6.6e-27	50.4
WP_012447492.1\|1099419_1099689_-	helix-turn-helix domain-containing protein	A0A088CD40	Shigella_phage	3.4e-06	35.9
WP_012447495.1\|1100261_1101470_-\|transposase	IS110 family transposase	A0A1X9I619	Streptococcus_phage	2.5e-35	28.3
WP_012447496.1\|1102009_1102258_+	hypothetical protein	NA	NA	NA	NA
WP_012447497.1\|1102560_1102851_+	nucleotidyltransferase domain-containing protein	NA	NA	NA	NA
WP_012447498.1\|1102843_1103176_+	DUF86 domain-containing protein	NA	NA	NA	NA
WP_012447499.1\|1103570_1103828_+	hypothetical protein	NA	NA	NA	NA
WP_012447501.1\|1104178_1104427_+	hypothetical protein	NA	NA	NA	NA
WP_012447502.1\|1104423_1104804_+\|protease	aspartyl protease family protein	A0A0A8WIU2	Clostridium_phage	1.6e-17	38.2
WP_012447503.1\|1105494_1106082_+	class I SAM-dependent methyltransferase	NA	NA	NA	NA
WP_012447504.1\|1106424_1107711_+	glycine/sarcosine/betaine reductase component B subunit	NA	NA	NA	NA
WP_012447505.1\|1108162_1109977_+	hypothetical protein	NA	NA	NA	NA
WP_012447506.1\|1110021_1111092_+	leucine-rich repeat domain-containing protein	NA	NA	NA	NA
WP_012447507.1\|1111502_1111907_+	hypothetical protein	NA	NA	NA	NA
WP_041366928.1\|1112334_1112739_+	hypothetical protein	NA	NA	NA	NA
WP_012447509.1\|1112866_1113544_+\|protease	CPBP family intramembrane metalloprotease	NA	NA	NA	NA
1114714:1114730	attR	NA	NA	NA	NA

DBSCAN-SWA_6

1531215 : 1595609

Bacillus_phage(46.15%)

protease,tRNA,transposase,integrase

attL 1568753:1568770|attR 1607771:1607788

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_012447917.1\|1531215_1532058_+\|protease	ATP-dependent Clp protease proteolytic subunit	NA	NA	NA	NA
WP_012447918.1\|1532057_1532288_+	YlzJ-like family protein	NA	NA	NA	NA
WP_012447437.1\|1533060_1534329_+	group II intron reverse transcriptase/maturase	A0A0U4J920	Pseudomonas_phage	2.3e-39	31.6
WP_012447919.1\|1534520_1535429_+	Na/Pi cotransporter family protein	NA	NA	NA	NA
WP_083762844.1\|1535908_1537966_+	DNA translocase FtsK	A0A218M9A2	Mycobacterium_phage	9.5e-88	48.2
WP_012447921.1\|1538172_1539096_+	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_012447922.1\|1539200_1540535_+	30S ribosomal protein S12 methylthiotransferase RimO	NA	NA	NA	NA
WP_012447923.1\|1540521_1541076_+	CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase	NA	NA	NA	NA
WP_012447924.1\|1541243_1541801_+	hypothetical protein	NA	NA	NA	NA
WP_012447925.1\|1541784_1543269_+	AAA family ATPase	E5ESM9	Bathycoccus_sp._RCC1105_virus	1.4e-69	36.5
WP_012447926.1\|1543367_1544588_+	competence/damage-inducible protein A	NA	NA	NA	NA
WP_012447927.1\|1544633_1546034_+	metallophosphoesterase	NA	NA	NA	NA
WP_012447928.1\|1546215_1547310_+	recombinase RecA	A0A0S2MVG1	Bacillus_phage	1.3e-120	62.0
WP_012447929.1\|1547315_1547774_+	regulatory protein RecX	NA	NA	NA	NA
WP_052291960.1\|1547916_1549461_+	ribonuclease Y	NA	NA	NA	NA
WP_012447931.1\|1549539_1550331_+	TIGR00282 family metallophosphoesterase	NA	NA	NA	NA
WP_012447932.1\|1550427_1550688_+	stage V sporulation protein S	J9PTX7	Bacillus_phage	6.5e-10	41.0
WP_012447933.1\|1550866_1551853_+	membrane dipeptidase	NA	NA	NA	NA
WP_012447934.1\|1551869_1552700_+	PHP domain-containing protein	NA	NA	NA	NA
WP_041366992.1\|1552936_1553914_+	GntR family transcriptional regulator	NA	NA	NA	NA
WP_012447936.1\|1553925_1554147_+	4Fe-4S binding protein	NA	NA	NA	NA
WP_148206827.1\|1554127_1555273_+	2-oxoacid:acceptor oxidoreductase subunit alpha	NA	NA	NA	NA
WP_012447938.1\|1555272_1556094_+	2-oxoacid:ferredoxin oxidoreductase subunit beta	NA	NA	NA	NA
WP_148206828.1\|1556074_1556644_+	2-oxoacid:acceptor oxidoreductase family protein	NA	NA	NA	NA
WP_012447940.1\|1556676_1557927_+	Glu/Leu/Phe/Val dehydrogenase	NA	NA	NA	NA
WP_012447941.1\|1558020_1559700_+	methylmalonyl-CoA mutase family protein	NA	NA	NA	NA
WP_012447942.1\|1559747_1560155_+	cobalamin B12-binding domain-containing protein	NA	NA	NA	NA
WP_012447943.1\|1560151_1560556_+	methylmalonyl-CoA epimerase	NA	NA	NA	NA
WP_012447944.1\|1560579_1562136_+	methylmalonyl-CoA carboxyltransferase	NA	NA	NA	NA
WP_012447945.1\|1562180_1562612_+	OadG family protein	NA	NA	NA	NA
WP_012447946.1\|1562663_1563098_+	biotin/lipoyl attachment domain-containing protein	NA	NA	NA	NA
WP_083762845.1\|1563185_1564226_+	sodium ion-translocating decarboxylase subunit beta	NA	NA	NA	NA
WP_012447948.1\|1564311_1565874_+	VanW family protein	NA	NA	NA	NA
WP_012447949.1\|1565879_1566065_-	hypothetical protein	NA	NA	NA	NA
WP_012447950.1\|1566280_1567636_+\|tRNA	tRNA (N6-isopentenyl adenosine(37)-C2)-methylthiotransferase MiaB	NA	NA	NA	NA
WP_012447951.1\|1567675_1570285_+	DNA mismatch repair protein MutS	A0A2I2L537	Orpheovirus	2.9e-33	23.3
1568753:1568770	attL	NA	NA	NA	NA
WP_012447952.1\|1570358_1572401_+	DNA mismatch repair endonuclease MutL	A0A1B2LRQ5	Wolbachia_phage	1.6e-79	32.0
WP_012447953.1\|1572456_1573455_+\|tRNA	tRNA (adenosine(37)-N6)-dimethylallyltransferase MiaA	NA	NA	NA	NA
WP_012447954.1\|1573520_1573775_+	RNA chaperone Hfq	NA	NA	NA	NA
WP_012447955.1\|1574976_1575768_+\|protease	CPBP family intramembrane metalloprotease	NA	NA	NA	NA
WP_148206912.1\|1575953_1576853_+	AAA family ATPase	G3MAX6	Bacillus_virus	1.5e-53	43.2
WP_148206829.1\|1576916_1578272_+	methionine gamma-lyase family protein	NA	NA	NA	NA
WP_012447958.1\|1578360_1579029_-	transcriptional repressor LexA	A0A1B1P7Q3	Bacillus_phage	6.6e-14	52.2
WP_012447959.1\|1579322_1579712_+	LysM peptidoglycan-binding domain-containing protein	NA	NA	NA	NA
WP_148206830.1\|1580518_1580914_-\|transposase	IS3 family transposase	A0A1P8CWQ3	Bacillus_phage	1.5e-10	47.5
WP_012447960.1\|1580898_1581165_-\|transposase	IS3 family transposase	A0A1P8CWP5	Bacillus_phage	1.4e-23	64.4
WP_012447961.1\|1581557_1582364_-	hypothetical protein	NA	NA	NA	NA
WP_012447962.1\|1582411_1583467_-	protein kinase	A0A1V0SGY7	Hokovirus	1.1e-10	30.2
WP_012447963.1\|1583503_1585435_-	KAP P-loop domain-containing protein	NA	NA	NA	NA
WP_012447964.1\|1585498_1586560_-	hypothetical protein	NA	NA	NA	NA
WP_012447965.1\|1586705_1587560_-	hypothetical protein	NA	NA	NA	NA
WP_012447966.1\|1587739_1588606_-	GIY-YIG nuclease family protein	NA	NA	NA	NA
WP_012447967.1\|1588931_1589945_-	hypothetical protein	NA	NA	NA	NA
WP_012447968.1\|1590030_1591758_-	ATP-dependent helicase	S5M596	Bacillus_phage	4.5e-06	21.8
WP_148206913.1\|1591792_1593544_-	AAA family ATPase	NA	NA	NA	NA
WP_012447970.1\|1594552_1594693_+	hypothetical protein	NA	NA	NA	NA
WP_041366995.1\|1594737_1595013_+\|integrase	site-specific integrase	NA	NA	NA	NA
WP_041366997.1\|1595099_1595609_+\|integrase	site-specific integrase	NA	NA	NA	NA
1607771:1607788	attR	NA	NA	NA	NA

DBSCAN-SWA_7

1662077 : 1669556

Bacillus_phage(50.0%)

transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_012448026.1\|1662077_1663382_+	UDP-glucose/GDP-mannose dehydrogenase family protein	A0A127AXI2	Bacillus_phage	2.8e-69	36.3
WP_012448027.1\|1663378_1664344_+	NAD-dependent epimerase/dehydratase family protein	A0A1V0SAI6	Catovirus	2.6e-35	29.5
WP_012448028.1\|1664360_1665227_+	UTP--glucose-1-phosphate uridylyltransferase GalU	A0A127AW70	Bacillus_phage	2.2e-70	49.0
WP_012448029.1\|1665328_1665532_-	cold-shock protein	Q9AZD3	Lactococcus_phage	4.0e-15	59.1
WP_012448030.1\|1666072_1666297_+	alpha/beta-type small acid-soluble spore protein	NA	NA	NA	NA
WP_012448031.1\|1666368_1666530_-	hypothetical protein	NA	NA	NA	NA
WP_012448032.1\|1666753_1666954_+	cold-shock protein	Q9AZD3	Lactococcus_phage	2.5e-17	64.6
WP_012448033.1\|1667047_1667464_-	DUF4870 domain-containing protein	NA	NA	NA	NA
WP_012448034.1\|1667488_1667677_-	hypothetical protein	NA	NA	NA	NA
WP_148206808.1\|1668414_1669556_-\|transposase	IS3 family transposase	A0A1P8CWQ3	Bacillus_phage	3.0e-99	64.2

DBSCAN-SWA_8

2023715 : 2091264

Leptospira_phage(27.27%)

coat,transposase,bacteriocin,integrase

attL 2084544:2084603|attR 2092958:2094217

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_012448356.1\|2023715_2024999_+\|transposase	IS110 family transposase	NA	NA	NA	NA
WP_012448357.1\|2025636_2027889_-	ankyrin repeat domain-containing protein	NA	NA	NA	NA
WP_012448358.1\|2028096_2028930_-	ATP-binding cassette domain-containing protein	G9BWD6	Planktothrix_phage	2.7e-17	28.2
WP_012448359.1\|2028914_2029631_-	cobalt transporter	NA	NA	NA	NA
WP_012448360.1\|2029636_2030416_-	energy-coupling factor ABC transporter permease	NA	NA	NA	NA
WP_012448361.1\|2030617_2031052_+	transcriptional repressor	NA	NA	NA	NA
WP_012448362.1\|2031048_2032152_-	histidinol-phosphate transaminase	A0A1X6WGT4	Pacmanvirus	2.8e-22	27.5
WP_012448363.1\|2032144_2033809_-	thiamine pyrophosphate-binding protein	H8ZJ31	Ostreococcus_tauri_virus	1.7e-31	25.6
WP_012448364.1\|2033871_2034960_-	DSD1 family PLP-dependent enzyme	NA	NA	NA	NA
WP_012448365.1\|2035138_2036812_+	amidohydrolase	NA	NA	NA	NA
WP_012448366.1\|2036808_2037300_-	hypothetical protein	NA	NA	NA	NA
WP_012448367.1\|2037472_2038054_-	TetR/AcrR family transcriptional regulator	NA	NA	NA	NA
WP_012448368.1\|2038073_2041178_-	efflux RND transporter permease subunit	S5VTK5	Leptospira_phage	3.1e-122	30.1
WP_012448369.1\|2041174_2042563_-	efflux RND transporter periplasmic adaptor subunit	NA	NA	NA	NA
WP_012448370.1\|2042586_2044161_-	TolC family protein	NA	NA	NA	NA
WP_012448372.1\|2045216_2045801_-	TetR/AcrR family transcriptional regulator	NA	NA	NA	NA
WP_012448373.1\|2045787_2048910_-	efflux RND transporter permease subunit	S5VTK5	Leptospira_phage	1.9e-119	28.6
WP_012448374.1\|2048909_2050262_-	efflux RND transporter periplasmic adaptor subunit	S5VL44	Leptospira_phage	8.6e-05	22.2
WP_012447151.1\|2050386_2051448_+\|transposase	IS6-like element ISNth1 family transposase	NA	NA	NA	NA
WP_012448375.1\|2051611_2053210_-	TolC family protein	NA	NA	NA	NA
WP_012448376.1\|2053399_2054866_-	amidase	NA	NA	NA	NA
WP_012448377.1\|2056538_2057423_-	pyridoxamine kinase	NA	NA	NA	NA
WP_012448378.1\|2058442_2058979_-	metallophosphoesterase	NA	NA	NA	NA
WP_012448379.1\|2058981_2059587_-	XTP/dITP diphosphatase	A0A0P0A2M4	Ugandan_cassava_brown_streak_virus	1.6e-11	30.7
WP_012448380.1\|2059592_2060333_-	ribonuclease PH	NA	NA	NA	NA
WP_012448381.1\|2060376_2061279_-	hypothetical protein	NA	NA	NA	NA
WP_012448382.1\|2061485_2062775_-	chloride channel protein	NA	NA	NA	NA
WP_012448383.1\|2063060_2064068_-	GerMN domain-containing protein	NA	NA	NA	NA
WP_012448384.1\|2064199_2065609_-	hypothetical protein	NA	NA	NA	NA
WP_012448385.1\|2065776_2066241_-	MarR family transcriptional regulator	NA	NA	NA	NA
WP_012448386.1\|2066355_2066805_-	DUF441 domain-containing protein	NA	NA	NA	NA
WP_012448387.1\|2066924_2067893_-	tripartite tricarboxylate transporter substrate binding protein	NA	NA	NA	NA
WP_012448388.1\|2067913_2068384_-	tripartite tricarboxylate transporter TctB family protein	NA	NA	NA	NA
WP_012448389.1\|2068380_2069910_-	tripartite tricarboxylate transporter permease	NA	NA	NA	NA
WP_012448390.1\|2070049_2070373_-	hypothetical protein	NA	NA	NA	NA
WP_012448391.1\|2070389_2070950_-	RNA 2',3'-cyclic phosphodiesterase	NA	NA	NA	NA
WP_012448392.1\|2071020_2071239_+	hypothetical protein	NA	NA	NA	NA
WP_012448393.1\|2071319_2071613_+\|coat	spore coat protein	NA	NA	NA	NA
WP_012448394.1\|2071675_2072359_-	spermine synthase	NA	NA	NA	NA
WP_012448395.1\|2072456_2074127_-	radical SAM protein	NA	NA	NA	NA
WP_012448396.1\|2074243_2076256_-	S9 family peptidase	A0A1V0SHT0	Klosneuvirus	1.5e-74	35.0
WP_012448397.1\|2076449_2076806_+	hypothetical protein	NA	NA	NA	NA
WP_041367710.1\|2076826_2077627_+\|bacteriocin	bacteriocin family protein	NA	NA	NA	NA
WP_012448399.1\|2077798_2078221_+	dUTP diphosphatase	A0A1S5XYX0	Kurlavirus	7.3e-27	46.4
WP_012448400.1\|2078295_2078550_+	YggT family protein	NA	NA	NA	NA
WP_012448401.1\|2078637_2078862_+	DUF3892 domain-containing protein	NA	NA	NA	NA
WP_012448402.1\|2078973_2080350_-	sodium:alanine symporter family protein	NA	NA	NA	NA
WP_012448403.1\|2080685_2081708_-	diguanylate cyclase	A0A127AWB9	Bacillus_phage	6.7e-18	36.4
WP_052291970.1\|2081944_2083255_+	bifunctional glutamate--cysteine ligase GshA/glutathione synthetase GshB	NA	NA	NA	NA
WP_052291971.1\|2083943_2084435_+	DUF2321 domain-containing protein	NA	NA	NA	NA
2084544:2084603	attL	NA	NA	NA	NA
WP_148206803.1\|2084583_2085725_-\|transposase	IS3 family transposase	A0A1P8CWQ3	Bacillus_phage	1.3e-99	64.6
WP_012448406.1\|2085829_2086453_+	hypothetical protein	NA	NA	NA	NA
WP_012448407.1\|2086442_2086985_+	hypothetical protein	NA	NA	NA	NA
WP_041367088.1\|2086981_2087206_+	hypothetical protein	NA	NA	NA	NA
WP_012448409.1\|2087452_2088601_-	AAA family ATPase	NA	NA	NA	NA
WP_012448410.1\|2088603_2091264_-\|integrase,transposase	DDE-type integrase/transposase/recombinase	NA	NA	NA	NA
2092958:2094217	attR	NA	NA	NA	NA

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage