CRISPRimmunity

Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NC_010655	Akkermansia muciniphila ATCC BAA-835, complete sequence	2 crisprs	csa3,DinG,cas3,cas2,cas1,cas9	0	6	0	0

1. NC_010655

CRISPR-Cas detection and classification

Crispr_ID: NC_010655_1

• CRISPR_ID: NC_010655_1
• CRISPR_location: 2438206-2438965
• CRISPR_type: TypeII
• Repeat_type: NA
• Spacer_info: 11 spacers
• Cas_protein_info: cas2,cas1,cas9

Consensus repeat of NC_010655_1

Consensus_repeat	Method
GTTTTGCCTTGAATCCAAAATAAGGCACAGTACAAC	CRISPRCasFinder
GTTTTGCCTTGAATCCAAAATAAGGCACAGTACAAC	CRT
GTTTTGCCTTGAATCCAAAATAAGGCACAGTACAAC	PILER-CR

spacers of NC_010655_1

>1.1|2438242|30|NC_010655|CRISPRCasFinder,CRT
AGACAGGGCTGGGGGACAAATACGTGGAGG
>1.2|2438308|30|NC_010655|CRISPRCasFinder,CRT
AGCACTACAGCATAATATCCAGAGCCAGAG
>1.3|2438374|30|NC_010655|CRISPRCasFinder,CRT
GTCTTTGTTCCTAATGGAAAGAACACCGTT
>1.4|2438440|30|NC_010655|CRISPRCasFinder,CRT,PILER-CR
CTTCGCATAACACACATAATGCAAAGTCGG
>1.5|2438506|29|NC_010655|CRISPRCasFinder,CRT,PILER-CR
TCATCACTCTTTCCGGCGTTCCCCTCATC
>1.6|2438571|30|NC_010655|CRISPRCasFinder,CRT,PILER-CR
CATTTGACAGGGGAGACTTCCATAAGCTCA
>1.7|2438637|30|NC_010655|CRISPRCasFinder,CRT,PILER-CR
AATATCTAAAATCCTCAAACCTCTACACCG
>1.8|2438703|30|NC_010655|CRISPRCasFinder,CRT,PILER-CR
GGAGGAACCTTCTACCCCTACGGACCTGCT
>1.9|2438769|29|NC_010655|CRISPRCasFinder,CRT,PILER-CR
TTGTGGCGCAGCATGCGCCGCGGCCATTG
>1.10|2438834|30|NC_010655|CRISPRCasFinder,CRT,PILER-CR
GTAGCGCAGGTAGAGCTGACGGATGATCAT
>1.11|2438900|30|NC_010655|CRISPRCasFinder,CRT,PILER-CR
GACTTTGATGCCGAAAATAATGCTTATCAT

CRISPR arrays and Neighbor proteins around NC_010655_1

CRISPR arrays

The CRISPR arrays of NC_010655_1

>merge|NC_010655|1|2438206-2438965|CRISPRCasFinder,CRT,PILER-CR
GTTTTGCCTTGAATCCAAAATAAGGCACAGTACAACAGACAGGGCTGGGGGACAAATACGTGGAGGGTTTTGCCTTGAATCCAAAATAAGGCACAGTACAACAGCACTACAGCATAATATCCAGAGCCAGAGGTTTTGCCTTGAATCCAAAATAAGGCACAGTACAACGTCTTTGTTCCTAATGGAAAGAACACCGTTGTTTTGCCTTGAATCCAAAATAAGGCACAGTACAACCTTCGCATAACACACATAATGCAAAGTCGGGTTTTGCCTTGAATCCAAAATAAGGCACAGTACAACTCATCACTCTTTCCGGCGTTCCCCTCATCGTTTTGCCTTGAATCCAAAATAAGGCACAGTACAACCATTTGACAGGGGAGACTTCCATAAGCTCAGTTTTGCCTTGAATCCAAAATAAGGCACAGTACAACAATATCTAAAATCCTCAAACCTCTACACCGGTTTTGCCTTGAATCCAAAATAAGGCACAGTACAACGGAGGAACCTTCTACCCCTACGGACCTGCTGTTTTGCCTTGAATCCAAAATAAGGCACAGTACAACTTGTGGCGCAGCATGCGCCGCGGCCATTGGTTTTGCCTTGAATCCAAAATAAGGCACAGTACAACGTAGCGCAGGTAGAGCTGACGGATGATCATGTTTTGCCTTGAATCCAAAATAAGGCACAGTACAACGACTTTGATGCCGAAAATAATGCTTATCATGTTTTGCCTTGAATCCAAAATAAGGCACAGTACAAC

>NC_010655|1|1|2438206-2438965|CRISPRCasFinder
GTTTTGCCTTGAATCCAAAATAAGGCACAGTACAAC	AGACAGGGCTGGGGGACAAATACGTGGAGG
GTTTTGCCTTGAATCCAAAATAAGGCACAGTACAAC	AGCACTACAGCATAATATCCAGAGCCAGAG
GTTTTGCCTTGAATCCAAAATAAGGCACAGTACAAC	GTCTTTGTTCCTAATGGAAAGAACACCGTT
GTTTTGCCTTGAATCCAAAATAAGGCACAGTACAAC	CTTCGCATAACACACATAATGCAAAGTCGG
GTTTTGCCTTGAATCCAAAATAAGGCACAGTACAAC	TCATCACTCTTTCCGGCGTTCCCCTCATC
GTTTTGCCTTGAATCCAAAATAAGGCACAGTACAAC	CATTTGACAGGGGAGACTTCCATAAGCTCA
GTTTTGCCTTGAATCCAAAATAAGGCACAGTACAAC	AATATCTAAAATCCTCAAACCTCTACACCG
GTTTTGCCTTGAATCCAAAATAAGGCACAGTACAAC	GGAGGAACCTTCTACCCCTACGGACCTGCT
GTTTTGCCTTGAATCCAAAATAAGGCACAGTACAAC	TTGTGGCGCAGCATGCGCCGCGGCCATTG
GTTTTGCCTTGAATCCAAAATAAGGCACAGTACAAC	GTAGCGCAGGTAGAGCTGACGGATGATCAT
GTTTTGCCTTGAATCCAAAATAAGGCACAGTACAAC	GACTTTGATGCCGAAAATAATGCTTATCAT
GTTTTGCCTTGAATCCAAAATAAGGCACAGTACAAC

>NC_010655|1|1|2438206-2438965|CRT
GTTTTGCCTTGAATCCAAAATAAGGCACAGTACAAC	AGACAGGGCTGGGGGACAAATACGTGGAGG
GTTTTGCCTTGAATCCAAAATAAGGCACAGTACAAC	AGCACTACAGCATAATATCCAGAGCCAGAG
GTTTTGCCTTGAATCCAAAATAAGGCACAGTACAAC	GTCTTTGTTCCTAATGGAAAGAACACCGTT
GTTTTGCCTTGAATCCAAAATAAGGCACAGTACAAC	CTTCGCATAACACACATAATGCAAAGTCGG
GTTTTGCCTTGAATCCAAAATAAGGCACAGTACAAC	TCATCACTCTTTCCGGCGTTCCCCTCATC
GTTTTGCCTTGAATCCAAAATAAGGCACAGTACAAC	CATTTGACAGGGGAGACTTCCATAAGCTCA
GTTTTGCCTTGAATCCAAAATAAGGCACAGTACAAC	AATATCTAAAATCCTCAAACCTCTACACCG
GTTTTGCCTTGAATCCAAAATAAGGCACAGTACAAC	GGAGGAACCTTCTACCCCTACGGACCTGCT
GTTTTGCCTTGAATCCAAAATAAGGCACAGTACAAC	TTGTGGCGCAGCATGCGCCGCGGCCATTG
GTTTTGCCTTGAATCCAAAATAAGGCACAGTACAAC	GTAGCGCAGGTAGAGCTGACGGATGATCAT
GTTTTGCCTTGAATCCAAAATAAGGCACAGTACAAC	GACTTTGATGCCGAAAATAATGCTTATCAT
GTTTTGCCTTGAATCCAAAATAAGGCACAGTACAAC

>NC_010655|1|1|2438404-2438965|PILER-CR
GTTTTGCCTTGAATCCAAAATAAGGCACAGTACAAC	CTTCGCATAACACACATAATGCAAAGTCGG
GTTTTGCCTTGAATCCAAAATAAGGCACAGTACAAC	TCATCACTCTTTCCGGCGTTCCCCTCATC
GTTTTGCCTTGAATCCAAAATAAGGCACAGTACAAC	CATTTGACAGGGGAGACTTCCATAAGCTCA
GTTTTGCCTTGAATCCAAAATAAGGCACAGTACAAC	AATATCTAAAATCCTCAAACCTCTACACCG
GTTTTGCCTTGAATCCAAAATAAGGCACAGTACAAC	GGAGGAACCTTCTACCCCTACGGACCTGCT
GTTTTGCCTTGAATCCAAAATAAGGCACAGTACAAC	TTGTGGCGCAGCATGCGCCGCGGCCATTG
GTTTTGCCTTGAATCCAAAATAAGGCACAGTACAAC	GTAGCGCAGGTAGAGCTGACGGATGATCAT
GTTTTGCCTTGAATCCAAAATAAGGCACAGTACAAC	GACTTTGATGCCGAAAATAATGCTTATCAT
GTTTTGCCTTGAATCCAAAATAAGGCACAGTACAAC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_010655.1|WP_012421038.1|2447047_2447977_+|cysteine-synthase-A	unknown	unknown	gnl|CDD|273463
NC_010655.1|WP_012421037.1|2445724_2447011_+|O-acetylhomoserine-aminocarboxypropyltransferase/cysteine-synthase	unknown	unknown	gnl|CDD|225428
NC_010655.1|WP_012421034.1|2440270_2443576_-|hypothetical-protein	cas9	cd09643_cas9_CAS-II-A:CAS-II-B:CAS-II-C	gnl|CDD|379160
NC_010655.1|WP_012421032.1|2439025_2439337_-|CRISPR-associated-endonuclease-Cas2	cas2	COG3512_cas2_CAS-II-A:CAS-II-B:CAS-II-C	gnl|CDD|226043
NC_010655.1|WP_012421039.1|2447995_2448610_+|thiamine-phosphate-synthase	unknown	unknown	gnl|CDD|234590
NC_010655.1|WP_012421022.1|2424790_2425813_-|DUF4105-domain-containing-protein	unknown	unknown	gnl|CDD|379156
NC_010655.1|WP_012421025.1|2429605_2430790_-|MFS-transporter	unknown	unknown	gnl|CDD|225365
NC_010655.1|WP_012421027.1|2433033_2434875_+|molecular-chaperone-HtpG	unknown	unknown	gnl|CDD|235366
NC_010655.1|WP_157738287.1|2430985_2432857_-|PRTRC-system-protein-C	unknown	unknown	gnl|CDD|379166
NC_010655.1|WP_012421023.1|2425873_2428393_-|phenylalanine--tRNA-ligase-subunit-beta	unknown	unknown	gnl|CDD|234804
NC_010655.1|WP_012421040.1|2448657_2449473_+|hydroxyethylthiazole-kinase	unknown	unknown	gnl|CDD|236477
NC_010655.1|WP_052294491.1|2436531_2436774_-|sel1-repeat-family-protein	unknown	unknown	gnl|CDD|276807
NC_010655.1|WP_157738288.1|2449781_2450246_+|DUF4065-domain-containing-protein	unknown	unknown	gnl|CDD|226128
NC_010655.1|WP_012421030.1|2437063_2438134_+|tyrosine-type-recombinase/integrase	unknown	unknown	gnl|CDD|271177
NC_010655.1|WP_012421024.1|2428413_2429439_-|phenylalanine--tRNA-ligase-subunit-alpha	unknown	unknown	gnl|CDD|234780
NC_010655.1|WP_012421033.1|2439324_2440260_-|type-II-CRISPR-associated-endonuclease-Cas1	cas1	cd09720_cas1_CAS-II-A:CAS-II-B:CAS-II-C	gnl|CDD|274694
NC_010655.1|WP_012421035.1|2443942_2445049_+|alanine-racemase	unknown	unknown	gnl|CDD|143481
NC_010655.1|WP_081429230.1|2435868_2436483_-|DUF805-domain-containing-protein	unknown	unknown	gnl|CDD|377540
NC_010655.1|WP_081429228.1|2434965_2435793_+|potassium-channel-family-protein	unknown	unknown	gnl|CDD|369572
NC_010655.1|WP_042449298.1|2445148_2445589_+|RrF2-family-transcriptional-regulator	unknown	unknown	gnl|CDD|273242

HMMScan for Signature genes

Protein	Cas_name	Cas_description	E-value	Identity	Coverage
NC_010655.1|WP_012421033.1|2439324_2440260_-|type-II-CRISPR-associated-endonuclease-Cas1	cas1	cd09720_cas1_CAS-II-A:CAS-II-B:CAS-II-C	2.3e-44	146.3	0.0
NC_010655.1|WP_012421034.1|2440270_2443576_-|hypothetical-protein	cas9	cd09643_cas9_CAS-II-A:CAS-II-B:CAS-II-C	6.5e-28	92.3	0.0
NC_010655.1|WP_012421032.1|2439025_2439337_-|CRISPR-associated-endonuclease-Cas2	cas2	COG3512_cas2_CAS-II-A:CAS-II-B:CAS-II-C	1.8e-29	97.1	0.0

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_010655.1|WP_012421038.1|2447047_2447977_+|cysteine-synthase-A	gnl|CDD|273463	TIGR01136, Cysteine_synthase, cysteine synthase. This model discriminates cysteine synthases (EC 2.5.1.47) (both CysK and CysM) from cystathionine beta-synthase, a protein found primarily in eukaryotes and carrying a C-terminal CBS domain lacking from this protein. Bacterial proteins lacking the CBS domain but otherwise showing resemblamnce to cystathionine beta-synthases and considerable phylogenetic distance from known cysteine synthases were excluded from the seed and score below the trusted cutoff. [Amino acid biosynthesis, Serine family].	4.5848e-167
NC_010655.1|WP_012421037.1|2445724_2447011_+|O-acetylhomoserine-aminocarboxypropyltransferase/cysteine-synthase	gnl|CDD|225428	COG2873, MET17, O-acetylhomoserine sulfhydrylase [Amino acid transport and metabolism].	0
NC_010655.1|WP_012421034.1|2440270_2443576_-|hypothetical-protein	gnl|CDD|379160	pfam13395, HNH_4, HNH endonuclease. This HNH nuclease domain is found in CRISPR-related proteins.	3.02251e-15
NC_010655.1|WP_012421032.1|2439025_2439337_-|CRISPR-associated-endonuclease-Cas2	gnl|CDD|226043	COG3512, COG3512, CRISPR-associated protein, Cas2 homolog [Defense mechanisms].	9.33042e-28
NC_010655.1|WP_012421039.1|2447995_2448610_+|thiamine-phosphate-synthase	gnl|CDD|234590	PRK00043, thiE, thiamine phosphate synthase.	1.14429e-78
NC_010655.1|WP_012421022.1|2424790_2425813_-|DUF4105-domain-containing-protein	gnl|CDD|379156	pfam13387, DUF4105, Domain of unknown function (DUF4105). This is a family of uncharacterized bacterial proteins. There is a highly conserved histidine residue and a well-conserved NCT motif.	7.34142e-25
NC_010655.1|WP_012421025.1|2429605_2430790_-|MFS-transporter	gnl|CDD|225365	COG2807, CynX, Cyanate permease [Inorganic ion transport and metabolism].	7.62107e-68
NC_010655.1|WP_012421027.1|2433033_2434875_+|molecular-chaperone-HtpG	gnl|CDD|235366	PRK05218, PRK05218, heat shock protein 90; Provisional.	0
NC_010655.1|WP_157738287.1|2430985_2432857_-|PRTRC-system-protein-C	gnl|CDD|379166	pfam13402, Peptidase_M60, Peptidase M60, enhancin and enhancin-like. This family of peptidases contains a zinc metallopeptidase motif (HEXXHX(8,28)E) and possesses mucinase activity. It includes the viral enhancins as well as enhancin-like peptidases from bacterial species. Enhancins are a class of metalloproteases found in some baculoviruses that enhance viral infection by degrading the peritrophic membrane (PM) of the insect midgut. Bacterial enhancins are found to be cytotoxic when compared to viral enhancin, however, suggesting that the bacterial enhancins do not enhance infection in the same way as viral enhancin. Bacterial enhancins may have evolved a distinct biochemical function. These bacterial domains are peptidases targetting host glycoproteins and thus probably play an important role in successful colonisation of both vertebrate mucosal surfaces and the invertebrate digestive tract by both mutualistic and pathogenic microbes. This family has been augmented by a merge with the sequences in the Enhancin Pfam family.	9.28639e-92
NC_010655.1|WP_012421023.1|2425873_2428393_-|phenylalanine--tRNA-ligase-subunit-beta	gnl|CDD|234804	PRK00629, pheT, phenylalanyl-tRNA synthetase subunit beta; Reviewed.	0
NC_010655.1|WP_012421040.1|2448657_2449473_+|hydroxyethylthiazole-kinase	gnl|CDD|236477	PRK09355, PRK09355, hydroxyethylthiazole kinase; Validated.	3.93531e-99
NC_010655.1|WP_052294491.1|2436531_2436774_-|sel1-repeat-family-protein	gnl|CDD|276807	sd00010, SLR, Sel1-like repeat. Sel1-like repeats (SLRs) share similar alpha-helical conformations with Tetratricopeptide repeats (TPRs), but with different consensus sequence lengths and superhelical topologies. SLRs contain 36 to 44 amino acids and are present in bacteria and eukaryotes but not in archaea. SLR proteins are involved in a variety of functions, and many serve as adaptor proteins for the assembly of macromolecular complexes. The SLR family was named after the Caenorhabditis elegans Sel1 protein which is predicted to fold into 11 SLRs, a transmembrane domain, and an N-terminal signal sequence. The human Sel1L protein contains an additional fibronectin type-II domain and an N-terminal PEST sequence. Its downregulation is associated with the development of breast and pancreatic carcinomas.	4.97405e-21
NC_010655.1|WP_157738288.1|2449781_2450246_+|DUF4065-domain-containing-protein	gnl|CDD|226128	COG3600, GepA, Uncharacterized phage-associated protein [Function unknown].	3.86963e-18
NC_010655.1|WP_012421030.1|2437063_2438134_+|tyrosine-type-recombinase/integrase	gnl|CDD|271177	cd00796, INT_Rci_Hp1_C, Shufflon-specific DNA recombinase Rci and Bacteriophage Hp1_like integrase, C-terminal catalytic domain. Rci protein is a tyrosine recombinase specifically involved in Shufflon type of DNA rearrangement in bacteria. The shufflon of plasmid R64 consists of four invertible DNA segments which are separated and flanked by seven 19-bp repeat sequences. RCI recombinase facilitates the site-specific recombination between any inverted repeats results in an inversion of the DNA segment(s) either independently or in groups. HP1 integrase promotes site-specific recombination of the HP1 genome into that of Haemophilus influenza. Bacteriophage Hp1_like integrases are tyrosine based site specific recombinases. They belong to the superfamily of DNA breaking-rejoining enzymes, which share the same fold in their catalytic domain and the overall reaction mechanism. The catalytic domain contains six conserved active site residues. Their overall reaction mechanism is essentially identical and involves cleavage of a single strand of a DNA duplex by nucleophilic attack of a conserved tyrosine to give a 3' phosphotyrosyl protein-DNA adduct. In the second rejoining step, a terminal 5' hydroxyl attacks the covalent adduct to release the enzyme and generate duplex DNA.	2.83131e-18
NC_010655.1|WP_012421024.1|2428413_2429439_-|phenylalanine--tRNA-ligase-subunit-alpha	gnl|CDD|234780	PRK00488, pheS, phenylalanyl-tRNA synthetase subunit alpha; Validated.	0
NC_010655.1|WP_012421033.1|2439324_2440260_-|type-II-CRISPR-associated-endonuclease-Cas1	gnl|CDD|274694	TIGR03639, cas1_NMENI, CRISPR-associated endonuclease Cas1, subtype II/NMENI. The CRISPR-associated protein Cas1 is virtually universal to CRISPR systems. CRISPR, an acronym for Clustered Regularly Interspaced Short Palindromic Repeats, is a prokaryotic immunity system for foreign DNA, mostly from phage. CRISPR systems belong to different subtypes, distinguished by both nature of the repeats, the makeup of the cohort of associated Cas proteins, and by molecular phylogeny within the more universal Cas proteins such as this one. This model is of type EXCEPTION and provides more specific information than the EQUIVALOG model TIGR00287. It describes the Cas1 variant of the NMENI subtype of CRISPR/Cas system.	5.48667e-46
NC_010655.1|WP_012421035.1|2443942_2445049_+|alanine-racemase	gnl|CDD|143481	cd00430, PLPDE_III_AR, Type III Pyridoxal 5-phosphate (PLP)-Dependent Enzyme Alanine Racemase. This family includes predominantly bacterial alanine racemases (AR), some serine racemases (SerRac), and putative bifunctional enzymes containing N-terminal UDP-N-acetylmuramoyl-tripeptide:D-alanyl-D-alanine ligase (murF) and C-terminal AR domains. These proteins are fold type III PLP-dependent enzymes that play essential roles in peptidoglycan biosynthesis. AR catalyzes the interconversion between L- and D-alanine, which is an essential component of the peptidoglycan layer of bacterial cell walls. SerRac converts L-serine into its D-enantiomer (D-serine) for peptidoglycan synthesis. murF catalyzes the addition of D-Ala-D-Ala to UDPMurNAc-tripeptide, the final step in the synthesis of the cytoplasmic precursor of bacterial cell wall peptidoglycan. Members of this family contain an N-terminal PLP-binding TIM-barrel domain and a C-terminal beta-sandwich domain. They exist as homodimers with active sites that lie at the interface between the TIM barrel domain of one subunit and the beta-sandwich domain of the other subunit. AR and other members of this family require dimer formation and the presence of the PLP cofactor for catalytic activity. Fungal ARs and eukaryotic serine racemases, which are fold types I and II PLP-dependent enzymes respectively, are excluded from this family.	3.06253e-159
NC_010655.1|WP_081429230.1|2435868_2436483_-|DUF805-domain-containing-protein	gnl|CDD|377540	pfam05656, DUF805, Protein of unknown function (DUF805). This family consists of several bacterial proteins of unknown function.	1.16351e-22
NC_010655.1|WP_081429228.1|2434965_2435793_+|potassium-channel-family-protein	gnl|CDD|369572	pfam07885, Ion_trans_2, Ion channel. This family includes the two membrane helix type ion channels found in bacteria.	4.71998e-13
NC_010655.1|WP_042449298.1|2445148_2445589_+|RrF2-family-transcriptional-regulator	gnl|CDD|273242	TIGR00738, Putative_HTH-type_transcriptional_regulator, Rrf2 family protein. This model represents a superfamily of probable transcriptional regulators. One member, RRF2 of Desulfovibrio vulgaris is an apparent regulatory protein experimentally (MEDLINE:97293189). The N-terminal region appears related to the DNA-binding biotin repressor region of the BirA bifunctional according to results after three rounds of PSI-BLAST with a fairly high stringency. [Unknown function, General].	3.23952e-43

Protein sequences

>NC_010655.1|WP_012421030.1|2437063_2438134_+|tyrosine-type-recombinase/integrase
MNIPTSSFPTDADQAGIFLIRSLGIPPMDAFLLLKDLLDTSRGRGDRITRAKRCIRLGGEALADREKSVSFSQAVRASLEARKHRRPRTLQEIRYMAARMMKKCPELARKQVRSITPEDCGRYLRKSFPTPRQRHKGRLILSGILNYSLKRGWCRRNAAFLVPPPILREKRIRALSLYEAKRLLHTAEQLFRGECLPACALMLYAGIRPHEVKRLTWKHINLKSGLVSLAPTHTKTGGSRHVSILPVLGSILSRMSSAGSPARSVCPPNWEKKWKEVRRRSGILKKSGWVQDVLRHTYASYHLAHFCNQNLLQKEMGHSSPSLLLARYLNMEGITSATGAMFWTHSFVSPAPLKED
>NC_010655.1|WP_052294491.1|2436531_2436774_-|sel1-repeat-family-protein
MLGDCYFFGNGVGKNKREAVNWYFLSAKKGNAEAQRRLGACFYFGHGVAKNRQEAIRWYRLAAEQGNTVAISMLKKLGVM
>NC_010655.1|WP_081429230.1|2435868_2436483_-|DUF805-domain-containing-protein
MKKVMEQSEERLSRIDAYNKLVDVAILTKTSSKAVADIVNNELGIECNASDVQEILKSSVSASDMHKIRREIEGNASIKMGNANRNLFLKKYVSFSGRISRSEYWVLKLLILPMMASILLCGVVMMWSKTGNDAGMLVLTVIIFICFIYFNIVADVRRLHDIGESGWWVFLKLVPLANIVIAAFLFFKGGQAVGNQHRDLRASH
>NC_010655.1|WP_081429228.1|2434965_2435793_+|potassium-channel-family-protein
MNSLRHMPRHVLFLRLAYQAGMCLLALVAVTLTAIDLTTEAAEWEVTADRIIYWIFVLDYVIRFSISRSKWLFVKEHPWDLLAIIPFDALFRLFRFASLGEILRLARYLDLFSYAMRFTTRIRRFFNTNGFKYICIAALVIILLGAVGIHLAEGMSLPNGIWWSFVTATTVGYGDTYPVTTSGKFLAVFLMLTGIGFVGTLTSTITSFFLSPHGGEALPYREEEIEAIKKKLDDLSSMTDEDIDTMAALLKTLRDASSAPPAEKEETPDIHSGKN
>NC_010655.1|WP_012421027.1|2433033_2434875_+|molecular-chaperone-HtpG
MNTETHQFQAEVRQLLDIVINALYSDREIFVRELVSNASDALEKLRLKQLTDSNIYQPDKPLEITVATDKENKTITIADTGIGMTEADLVENLGTIAHSGTKKFMEALKQKQEGGADLIGQFGVGFYSSFMVADRVEVFTRSYEPEAASLRWSSDGREGYSIETLAEPLDRGTRIVIRLKDEYEEFSQEYRVKELLRRYSNFVGFPLNFNGEHINTVQAIWSKSKSDVKPEEYDEFYQFISHTDEKPLSYMHFSADAPIALNALLFIPRRNPEMFGFGRVDANVALYCKRVLIDAKPEGLLPEWLRFLNGVVDSEDLPLNISREMLQDNSLVRKISDIITRRFIKHLEKLAKDDKETYREFYAQFSRYLKEGVVTSWPNKESLGKLLRFESTSTEPGETTSFEEYLTRMKEGQTAIYALTGPSRSHLENSPYLEAFKARGYEVAFFTDHGDEFVLDSLSSVDGKPVTMIDRADVELPALEEEQKDALPQEEAAALEEWLKGLYPDKFSKVTLGKRLVSGAAVALQSGNDMGPEMRAYMKAMGQEVPESHPQLELNPSNPLVKKLSALRTENPELAQMVADQIANTALLRAGMLDDPAVLAQSSQALMEQLLLK
>NC_010655.1|WP_157738287.1|2430985_2432857_-|PRTRC-system-protein-C
MIFSPLLKKGVLLLALCGVLGGGVLSAQEAGGAPITEEGLKALDSNVFANEYMLALKPNVTRDRIARIKDPFVRGLATRMAEKKFDRKARALTAEPYEPVKDLAERLRTSQYSKFENPTGIFFEEGEDVLLVMGDPKGEKLNLVIHNFGRDGGHSSYPLKEGVNIIRAKNKGLGYIEYFTPNYKKAPKVHLSILSGKVNGVFVGGVSKNSDWKKMLENSPTEVVDIVGSRVHLVYPVEELKQFCPDKGEELIALYDRIIGMEQQIMGLYKYRMLPKNRMFGRVIWNGFMHADGTGAAFHNGTMKEVGNPDRIPGSAWGIAHEFGHVNQVRPAMKWVSTGEVTNNIYSAYVNYMLNPSSMRLEHERINGGDGNMIGGRFNAYLNNGILKGENWLVQSGPDKRSGGDNRPMVHDHFVKLAPLWQLELYFKVAGKGNPDFYPDIFYKAIKMDTRGKKDGELQLAFMKNACDAARQDLTDFFRKTGMLKPIDQELDDYTCARMTITEADCKNLIAYARKYKKPESPVIYYISVNSAEAYKNRLPVRGVYNQGVTEQGNRRVVSHDVWKNAVVFETYKDREMVRITMVGTDSRDNSSTTVPYPEGSTRIEAVSWDGRRTLVYGKRPAK
>NC_010655.1|WP_012421025.1|2429605_2430790_-|MFS-transporter
MDKAGTSGGIRGKMLLFVAFLIVCFNLRTGFDSPDPLLGTIERDMGLSLENSGLFALLPVFVLGVAAPISPRVARWMTPWKIIFWFQLLAVAGIFWRSWDGVAGLYGGMVLMGLGMGIAGAAIPGLIKHQFPDHASAMMGVYSAMIGVGSAAASGLSVPISNMLGGWRFGLGVWIIPILLGMLVWGAYFLRHPAGVFQSDPAASGHNLLRSGKAWQVTVFYLSRVGAAYFFYTWIPIFLRQRGMSYEDAGFILSVAMFAQLPATLSAHVLEKATGGRGLLIVMAMALAALSCWGILYLPPDWALWMAILFGLATGTVFSRGMALMVERARTPSESIRLSGMSQGIGFTMGALLSLLFTSFLHQGGSFLPFCLVYTFFCVLGMVSGRMSARPGYV
>NC_010655.1|WP_012421024.1|2428413_2429439_-|phenylalanine--tRNA-ligase-subunit-alpha
MKEEIVRIQRDALARIAQASDRRGVEDARVAILGKKGELTLAQTGMKDVPREEKPAVGQLLNEARKAITEALDAKLEEVQAQADKAAVAGVDLTLPARSLPPGGLHPLTIVRDEAVRILRHMGFALADGPEIEDEFHCFDALNTPEDHPARNEKDTFYFDSGKLLRTHTSSVQIRSMEKQLPPVRVIAPGSAYRRDEIDATHLSAFNQLEGLYVDTDVSVGDLKGTLEYFLRALFGSGTEVRFRPHFFPFTEPSFEIDVKLKVDGQAPRWVEIAGCGMVDPNVFEAVDRELGLDPGAQARYTGLTGFAFGIGLDRLAMIRWGIRDIRALIENDVRFLAQFQ
>NC_010655.1|WP_012421023.1|2425873_2428393_-|phenylalanine--tRNA-ligase-subunit-beta
MKISLNWLSQYIDLSGLSVDEMSDMLTFAGIEVEDIRQQGVDSPYVVVARVASAEQHPQADRLKVCQVDVGDGTLHQIVCGAQNYKVGDKVPCALPGAVLPGNVEIKVGKLRGVESRGMLCSASELGLPDKEHGLWILPQELEPGTPISQVVKADTLVEVEVTPNRPDLLSHNGMAYELAAISGRGYRPVSIDDAGVALEPAGDFVRLDQPELNPYYTAVKISGVKVQESPEWLKERLVAVGLRPINNIVDITNFVLHELGTPLHAFDAAKVQGGIVTRTAYEGETIKALDGQEYTLNCTDLVVADQSGKALAIGGVMGGEESGVTDATTDIILESAWFKPSSVRATSRRLALSSDSSYRFERGTSAWNVLRGSVRAVELILQLAGGTASPTYVAGSPVPNPAHASMPSCGGADGPVSVFASLKQGKGATVTNELGFVQLPWKALDQISGGSISHEEGTRILTALGLKQVPDSPECWLIPPHRLDLTRPCDLLEEIVRVFGLDGIPSRFSGPFVAESPVDVAYNFQMELRRKLAALGFYETQTIKLIASESADGTIAQVKDALPLRPLQDGDLIRVSLPLSEDHSVLRPAHTPGLIAAAVRNSNQGVSGLRFFELGRVFRNTGGGKGRDIETDTLGILVSGDRTARSWADPRPEQASFEDLLAVMAALAPGHRFTLTPARPREQAALGADVQLDGKACGYFARLSLARCRELGLGQPVYVAELDLRKMQEILTAPVKAAELPQFPGSSRDAAMELPLSTPNADIVKAVESAREKLLVSYFCFDVFTDPSGEKLPADRKSIAYTFLYRDPAKTLTAAEVDAAHQRVLKALTDKVKGLSFR
>NC_010655.1|WP_012421022.1|2424790_2425813_-|DUF4105-domain-containing-protein
MHLTFLRRACPAAARILMTAAWFCFSVWAAGVVFYNVWGGAVLVWLYVAAMACAFALRGKRPVLWRASWGVPALLLAYYLCIPATNDKEWQPSWSRLPSVEINGNEIVVKDVRSFIYRTERDFDARYVTRRFDLDKLATLDFAVSHWDGMEFVAHTMLSFGFEDGKHLALSVETRLPEGVEQGTVPGLYKQFNVIYILADEEDLFALRTNYRKEDMYLYRINIGRESLKKAFLGFAEKINSLHERPRYYHTVTANCTTELVDTFKSYLGVRRWQWTPVFNGMCDQNAYDRGELLHLPGESFRELKKRSFLGHGGNGEDWPALRRRWEEGWRTFASTPVKE
>NC_010655.1|WP_012421032.1|2439025_2439337_-|CRISPR-associated-endonuclease-Cas2
MGWLVVFFDLPTTTPEDKKNYQYFRKALLEDGYTMIQYSVYARACVTQERMATHSRRIQKMIPPDGSVRCLFVTNIQWDKMFVFHGRSCPRQEVSLPQQMLLW
>NC_010655.1|WP_012421033.1|2439324_2440260_-|type-II-CRISPR-associated-endonuclease-Cas1
MSYHILSIDAYTCHLSCDKGQLRCADGENSPRTIPLEDVGAVVLSSFKATLTSNLLIELARKRIGFVLCESYRPAVLLLPADRSTDTGLLRHLADMPARLRNRLWQKTLDAKCGNQTALAQAWNPHHPAIAELKRMAVTEKTAREAECARLFWSVFADTWANSDFRRGRHEEGFNNLFNYAYAILLSCILQYLFALGLDPCFGIFHQSREHAAPLAYDLMEPFRPAFDANVARWIHLCLREGKTEERAGEITREFRQHITATLQASVMYRDKQLPLKAAVEAVCRSFRKAVLAGQSEPYEPWLMTTIKWAG
>NC_010655.1|WP_012421034.1|2440270_2443576_-|hypothetical-protein
MSRSLTFSFDIGYASIGWAVIASASHDDADPSVCGCGTVLFPKDDCQAFKRREYRRLRRNIRSRRVRIERIGRLLVQAQIITPEMKETSGHPAPFYLASEALKGHRTLAPIELWHVLRWYAHNRGYDNNASWSNSLSEDGGNGEDTERVKHAQDLMDKHGTATMAETICRELKLEEGKADAPMEVSTPAYKNLNTAFPRLIVEKEVRRILELSAPLIPGLTAEIIELIAQHHPLTTEQRGVLLQHGIKLARRYRGSLLFGQLIPRFDNRIISRCPVTWAQVYEAELKKGNSEQSARERAEKLSKVPTANCPEFYEYRMARILCNIRADGEPLSAEIRRELMNQARQEGKLTKASLEKAISSRLGKETETNVSNYFTLHPDSEEALYLNPAVEVLQRSGIGQILSPSVYRIAANRLRRGKSVTPNYLLNLLKSRGESGEALEKKIEKESKKKEADYADTPLKPKYATGRAPYARTVLKKVVEEILDGEDPTRPARGEAHPDGELKAHDGCLYCLLDTDSSVNQHQKERRLDTMTNNHLVRHRMLILDRLLKDLIQDFADGQKDRISRVCVEVGKELTTFSAMDSKKIQRELTLRQKSHTDAVNRLKRKLPGKALSANLIRKCRIAMDMNWTCPFTGATYGDHELENLELEHIVPHSFRQSNALSSLVLTWPGVNRMKGQRTGYDFVEQEQENPVPDKPNLHICSLNNYRELVEKLDDKKGHEDDRRRKKKRKALLMVRGLSHKHQSQNHEAMKEIGMTEGMMTQSSHLMKLACKSIKTSLPDAHIDMIPGAVTAEVRKAWDVFGVFKELCPEAADPDSGKILKENLRSLTHLHHALDACVLGLIPYIIPAHHNGLLRRVLAMRRIPEKLIPQVRPVANQRHYVLNDDGRMMLRDLSASLKENIREQLMEQRVIQHVPADMGGALLKETMQRVLSVDGSGEDAMVSLSKKKDGKKEKNQVKASKLVGVFPEGPSKLKALKAAIEIDGNYGVALDPKPVVIRHIKVFKRIMALKEQNGGKPVRILKKGMLIHLTSSKDPKHAGVWRIESIQDSKGGVKLDLQRAHCAVPKNKTHECNWREVDLISLLKKYQMKRYPTSYTGTPR
>NC_010655.1|WP_012421035.1|2443942_2445049_+|alanine-racemase
MPATSPPRAWAEIDLGAIRHNLNVVKQAAKGEYYMPVVKAGAYGHGLEQVCRTLDSEGIAFFGVANVGEARRISQAGCRTRPYILGPAFPEEREEIVLNGWRSFISTMEEAAHYNSLARLYGKTLPIHLSVDTGMGRGGFLPDQLEELLSRLGELDSLHLEGLGAHLPCADEDREITLRQISRFEQMAARIREKLPLKYCHLANSAASLDYEIPSNNMCRPGLVLYGFSPIPSPWAAQLKPAMALFSRLTVVRTLPEGHGISYGGTFVTDHPTRVATVGIGYADGYLRSLAHKGARVMVDGVSCPLLGRVTMDQIMVDVSRAPHAEPGMTAEIMGPHIPVTELAEKAGTISWEIFTGIGPRVPRHYTH
>NC_010655.1|WP_042449298.1|2445148_2445589_+|RrF2-family-transcriptional-regulator
MKVSTRGRYALRLMIDLAQHRDEGYISLKEISARQDVTVRYLEQIIAILLKAGFVQSFRGKAGGYRLSRHPREYTTEDILKLTEGSLLPLSCTASHENPCPRAAGCATLPFWRGLQQVIENYLRRVTLEDLAEQQKEIGCDYGAGI
>NC_010655.1|WP_012421037.1|2445724_2447011_+|O-acetylhomoserine-aminocarboxypropyltransferase/cysteine-synthase
MSKNHRFETRQIHVGQESPDPATDARAVPIYATTSYVFKDSEQAAGRFALAEPGNIYNRLMNPTADVFEKRIASLEGGTAALAVSTGAAAVTYAIQNIARAGDHIVSSSTVYGGTYNLFANTLADAGIETTFVDARDVQNFSRAIRNNTKALYVESLGNPNCDIVDMEALAEVAHAHGIPLIVDSTFATPFLFRPLEHGADIVVHSATKFIGGHGTVMGGVIVDGGKFDWTQNDKFPGISKPNPNYHGAVFAEVCGNLAYIVKIRATLLRDTGATISPFNSFLLLQGLETLSLRVERHVQNALRVADYLASHPQVERVNHPSLPDHPDHDLYKRYYPNGGGSIFTFEIKGGAEKARKFCESLELFSLLANVADVKSLVIHPASTTHSQMTEEELKAGGITPSTVRLSIGTEHIDDILEDLEQGFRAIL
>NC_010655.1|WP_012421038.1|2447047_2447977_+|cysteine-synthase-A
MRIYKNITELIGGTPLLELTNYERRNGLNATLLAKLEYLNPAGSVKDRIAQAMIDAAEAAGKLKPDSVIIEPTSGNTGIGLAAVATSRGYRIILTMPETMSVERRNLLKAYGAELVLTDGALGMKGAISKAEELAAGLPNSFIPGQFANPSNPEAHFRTTGPEIWNDTEGKADIFVAGVGTGGTITGVGKYLKTRNPDIRIVAVEPFSSPVLTQGTAGPHKIQGIGAGFVPGTLDTSVYDEVIAVTNEDAFSTGKELARTDGVLTGISSGAALWAATQVARRPENEGKTIVVLLPDTGDRYLSTPLFTD
>NC_010655.1|WP_012421039.1|2447995_2448610_+|thiamine-phosphate-synthase
MKKFNLHLYLVTDEASKCRLSLLETVRKAADGGVTIVQYRSTNPDAGTCYREALPIRDFLASRGIPFIVNNRIDLALALEADGVHIGQRDLPVPSVRAMIGPDKILGLSVSNKEQLRAVDASLVDYLGMGPVFPTISKLNAPPVLGVEGFAALASQSPLPVVAIGGLDAERARQVRATGTASGIAVVSAICGAENPETAARALA
>NC_010655.1|WP_012421040.1|2448657_2449473_+|hydroxyethylthiazole-kinase
MLSSTDLVQAVTADLGKIRETAPLVLSLTNSVVQPLTANLLLAIGAVPAMLNDAEEAVDMLRSGTGALLVNLGTVTREQGAAMQTAVREANRLNIPWVLDPVAVGALSLRTRLAGQLKEQSPRIIRGNASEIMALAGYSSVTKGPESTSSSADALHAARELALHTGAAVLVTGRTDYSTDGRQVTATENGHAMMSRVTGVGCSMGALSAACAAVSPTPLQAAVSTAVLMGIAGEMAFEQSPSPGSFAVSLLDSLYALSPEDVVRRARFLSL
>NC_010655.1|WP_157738288.1|2449781_2450246_+|DUF4065-domain-containing-protein
MANSTTTQKLCNWFIQQANAKELILTPVKLNHLVILADWWHLHRTGAFLINERVEAWPSGPVLPSIYHEYKDQPPYSSIEHPSRRQPPLEEETDIIPFLEHIWNVYGKYTAQQLGRINTAPSSPWKQSQGKHEQAHRQQITEEHVQAYFKSLAG

Crispr_ID: NC_010655_2

• CRISPR_ID: NC_010655_2
• CRISPR_location: 2507588-2507825
• CRISPR_type: Orphan
• Repeat_type: NA
• Spacer_info: 3 spacers

Consensus repeat of NC_010655_2

Consensus_repeat	Method
GTTTCAATCCACGCACTCCTTGCGGAGTGCGAC	CRISPRCasFinder
GTTTCAATCCACGCACTCCTT	CRT
GTTTCAATCCACGCACTCCTTGCGGAGTGCGAC	PILER-CR

spacers of NC_010655_2

>2.1|2507621|35|NC_010655|CRISPRCasFinder
GGATGTTGTGACGGCCAGACAAGCAACGAGCAATA
>2.2|2507689|37|NC_010655|CRISPRCasFinder
TTTCTATTGTTTTTATCCTCCGGAATCCGGGGTACAG
>2.3|2507759|34|NC_010655|CRISPRCasFinder
ATAATATGACCATTGTAGCTGATAATATATGGGG
>2.4|2507609|47|NC_010655|CRT
ACGGAGTGCGACGGATGTTGTGACGGCCAGACAAGCAACGAGCAATA
>2.5|2507677|49|NC_010655|CRT
GCGGAGTGCGACTTTCTATTGTTTTTATCCTCCGGAATCCGGGGTACAG
>2.6|2507747|46|NC_010655|CRT
GCGGAGTGCGACATAATATGACCATTGTAGCTGATAATATATGGGG
>2.7|2507622|35|NC_010655|PILER-CR
GGATGTTGTGACGGCCAGACAAGCAACGAGCAATA
>2.8|2507690|37|NC_010655|PILER-CR
TTTCTATTGTTTTTATCCTCCGGAATCCGGGGTACAG

CRISPR arrays and Neighbor proteins around NC_010655_2

CRISPR arrays

The CRISPR arrays of NC_010655_2

>merge|NC_010655|2|2507588-2507825|CRISPRCasFinder,CRT,PILER-CR
TTTTCAATCCACGCACTCCTTACGGAGTGCGACGGATGTTGTGACGGCCAGACAAGCAACGAGCAATAGTTTCAATCCACGCACTCCTTGCGGAGTGCGACTTTCTATTGTTTTTATCCTCCGGAATCCGGGGTACAGGTTTCAATCCACGCACTCCTTGCGGAGTGCGACATAATATGACCATTGTAGCTGATAATATATGGGGGTTTCAATCCACGCACTCATGAGAGTGCGACTC

>NC_010655|2|2|2507588-2507825|CRISPRCasFinder
TTTTCAATCCACGCACTCCTTACGGAGTGCGAC	GGATGTTGTGACGGCCAGACAAGCAACGAGCAATA
GTTTCAATCCACGCACTCCTTGCGGAGTGCGAC	TTTCTATTGTTTTTATCCTCCGGAATCCGGGGTACAG
GTTTCAATCCACGCACTCCTTGCGGAGTGCGAC	ATAATATGACCATTGTAGCTGATAATATATGGGG
GTTTCAATCCACGCACTCATGAGAGTGCGACTC

>NC_010655|2|2|2507588-2507813|CRT
TTTTCAATCCACGCACTCCTT	ACGGAGTGCGACGGATGTTGTGACGGCCAGACAAGCAACGAGCAATA
GTTTCAATCCACGCACTCCTT	GCGGAGTGCGACTTTCTATTGTTTTTATCCTCCGGAATCCGGGGTACAG
GTTTCAATCCACGCACTCCTT	GCGGAGTGCGACATAATATGACCATTGTAGCTGATAATATATGGGG
GTTTCAATCCACGCACTCATG

>NC_010655|2|2|2507589-2507758|PILER-CR
TTTCAATCCACGCACTCCTTACGGAGTGCGACG	GATGTTGTGACGGCCAGACAAGCAACGAGCAATAG
TTTCAATCCACGCACTCCTTGCGGAGTGCGACT	TTCTATTGTTTTTATCCTCCGGAATCCGGGGTACAGG
TTTCAATCCACGCACTCCTTGCGGAGTGCGAC

Neighbor Proteins Overview

Protein	Signature genes	Signature genes Name	Protein_function
NC_010655.1|WP_012421091.1|2513580_2514576_-|hypothetical-protein	unknown	unknown	unknown
NC_010655.1|WP_012421079.1|2500652_2500997_-|rubrerythrin	unknown	unknown	gnl|CDD|275328
NC_010655.1|WP_031931498.1|2514575_2515025_-|KH-domain-containing-protein	unknown	unknown	gnl|CDD|224760
NC_010655.1|WP_012421097.1|2521931_2522528_+|GNAT-family-N-acetyltransferase	unknown	unknown	gnl|CDD|379112
NC_010655.1|WP_012421090.1|2509840_2513422_-|bifunctional-proline-dehydrogenase/L-glutamate-gamma-semialdehyde-dehydrogenase	unknown	unknown	gnl|CDD|143443
NC_010655.1|WP_012421086.1|2506303_2506924_+|hypothetical-protein	unknown	unknown	gnl|CDD|222807
NC_010655.1|WP_012421081.1|2501804_2502308_-|thioredoxin-family-protein	unknown	unknown	gnl|CDD|379034
NC_010655.1|WP_042448418.1|2501279_2501624_-|rubrerythrin	unknown	unknown	gnl|CDD|275328
NC_010655.1|WP_012421095.1|2521054_2521630_-|rubrerythrin-family-protein	unknown	unknown	gnl|CDD|153100
NC_010655.1|WP_012421099.1|2523251_2525708_-|DNA-translocase-FtsK	unknown	unknown	gnl|CDD|224588
NC_010655.1|WP_012421088.1|2507264_2507522_+|hypothetical-protein	unknown	unknown	unknown
NC_010655.1|WP_081429233.1|2515537_2517805_+|catalase-HPII	unknown	unknown	gnl|CDD|236886
NC_010655.1|WP_143245884.1|2505772_2505979_-|hypothetical-protein	unknown	unknown	unknown
NC_010655.1|WP_012421082.1|2502977_2503859_-|hypothetical-protein	unknown	unknown	unknown
NC_010655.1|WP_012421083.1|2503851_2504133_-|hypothetical-protein	unknown	unknown	unknown
NC_010655.1|WP_031931492.1|2506974_2507268_+|BlaI/MecI/CopY-family-transcriptional-regulator	unknown	unknown	gnl|CDD|367747
NC_010655.1|WP_143245883.1|2518312_2521006_-|cytochrome-c-biogenesis-protein-CcsA	unknown	unknown	gnl|CDD|274447
NC_010655.1|WP_012421089.1|2508221_2509376_-|acyltransferase	unknown	unknown	gnl|CDD|376607
NC_010655.1|WP_143245882.1|2522602_2523232_-|hypothetical-protein	unknown	unknown	unknown
NC_010655.1|WP_012421084.1|2504129_2505764_-|head-tail-connector-protein	unknown	unknown	gnl|CDD|378829

rpsblast for functional proteins

Protein	Function_ID	Function_description	E-value
NC_010655.1|WP_012421079.1|2500652_2500997_-|rubrerythrin	gnl|CDD|275328	TIGR04535, conserved_hypothetical_protein, ferritin-like protein. Two families of proteins are known to be encoded, with some regularity, next to the gene for encapsulin (pfam04454), with surrounds the target protein to form a prokaryotic proteinaceous organelle. One is the family of enzymes that includes Dyp-type peroxidases. The other is this family, with a resemblance to bacterioferritins. Encapsulin-associated forms of the proteins in these two families have a necessary C-terminal motif that resembles DGSL[SGN]IGSL[KR]. Members of this family that include the last columns of the model in the hit region (and are encoded next to the encapsulin gene) should be designated encapsulin-associated ferritin-like protein.	1.15018e-18
NC_010655.1|WP_031931498.1|2514575_2515025_-|KH-domain-containing-protein	gnl|CDD|224760	COG1847, Jag, Predicted RNA-binding protein [General function prediction only].	4.91528e-30
NC_010655.1|WP_012421097.1|2521931_2522528_+|GNAT-family-N-acetyltransferase	gnl|CDD|379112	pfam13302, Acetyltransf_3, Acetyltransferase (GNAT) domain. This domain catalyzes N-acetyltransferase reactions.	2.68448e-28
NC_010655.1|WP_012421090.1|2509840_2513422_-|bifunctional-proline-dehydrogenase/L-glutamate-gamma-semialdehyde-dehydrogenase	gnl|CDD|143443	cd07125, ALDH_PutA-P5CDH, Delta(1)-pyrroline-5-carboxylate dehydrogenase, PutA. The proline catabolic enzymes of the aldehyde dehydrogenase (ALDH) protein superfamily, proline dehydrogenase and Delta(1)-pyrroline-5-carboxylate dehydrogenase (P5CDH, (EC=1.5.1.12 )), catalyze the two-step oxidation of proline to glutamate; P5CDH catalyzes the oxidation of glutamate semialdehyde, utilizing NAD+ as the electron acceptor. In some bacteria, the two enzymes are fused into the bifunctional flavoenzyme, proline utilization A (PutA) These enzymes play important roles in cellular redox control, superoxide generation, and apoptosis. In certain prokaryotes such as Escherichia coli, PutA is also a transcriptional repressor of the proline utilization genes.	0
NC_010655.1|WP_012421086.1|2506303_2506924_+|hypothetical-protein	gnl|CDD|222807	PHA00662, PHA00662, hypothetical protein.	1.96191e-22
NC_010655.1|WP_012421081.1|2501804_2502308_-|thioredoxin-family-protein	gnl|CDD|379034	pfam13098, Thioredoxin_2, Thioredoxin-like domain.	1.707e-13
NC_010655.1|WP_042448418.1|2501279_2501624_-|rubrerythrin	gnl|CDD|275328	TIGR04535, conserved_hypothetical_protein, ferritin-like protein. Two families of proteins are known to be encoded, with some regularity, next to the gene for encapsulin (pfam04454), with surrounds the target protein to form a prokaryotic proteinaceous organelle. One is the family of enzymes that includes Dyp-type peroxidases. The other is this family, with a resemblance to bacterioferritins. Encapsulin-associated forms of the proteins in these two families have a necessary C-terminal motif that resembles DGSL[SGN]IGSL[KR]. Members of this family that include the last columns of the model in the hit region (and are encoded next to the encapsulin gene) should be designated encapsulin-associated ferritin-like protein.	9.48792e-18
NC_010655.1|WP_012421095.1|2521054_2521630_-|rubrerythrin-family-protein	gnl|CDD|153100	cd01041, Rubrerythrin, Rubrerythrin, ferritin-like diiron-binding domain. Rubrerythrin domain is a nonheme iron binding domain found in many air-sensitive bacteria and archaea and member of a broad superfamily of ferritin-like diiron-carboxylate proteins. The homodimeric rubrerythrin protein contains a binuclear metal center located within a four helix bundle. Many, but not all, rubrerythrin proteins have a second domain with a rubredoxin-like hexacoordinated iron center. Rubrerythrin is thought to reduce hydrogen peroxide as part of an oxidative stress protection system but its function is still poorly understood.	9.03876e-56
NC_010655.1|WP_012421099.1|2523251_2525708_-|DNA-translocase-FtsK	gnl|CDD|224588	COG1674, FtsK, DNA segregation ATPase FtsK/SpoIIIE and related proteins [Cell division and chromosome partitioning].	9.37422e-134
NC_010655.1|WP_081429233.1|2515537_2517805_+|catalase-HPII	gnl|CDD|236886	PRK11249, katE, hydroperoxidase II; Provisional.	0
NC_010655.1|WP_143245883.1|2518312_2521006_-|cytochrome-c-biogenesis-protein-CcsA	gnl|CDD|274447	TIGR03144, cytochrome_c_biogenesis_protein_chloroplast, cytochrome c-type biogenesis protein CcsB. Members of this protein family represent one of two essential proteins of system II for c-type cytochrome biogenesis. Additional proteins tend to be part of the system but can be replaced by chemical reductants such as dithiothreitol. This protein is designated CcsB in Bordetella pertussis and some other bacteria, resC in Bacillus (where there is additional N-terminal sequence), and CcsA in chloroplast. We use the CcsB designation here. Member sequences show regions of strong sequence conservation and variable-length, poorly conserved regions in between; sparsely filled columns were removed from the seed alignment prior to model construction. [Energy metabolism, Electron transport, Protein fate, Protein modification and repair].	1.37215e-34
NC_010655.1|WP_031931492.1|2506974_2507268_+|BlaI/MecI/CopY-family-transcriptional-regulator	gnl|CDD|367747	pfam03965, Penicillinase_R, Penicillinase repressor. The penicillinase repressor negatively regulates expression of the penicillinase gene. The N-terminal region of this protein is involved in operator recognition, while the C-terminal is responsible for dimerization of the protein.	1.33159e-06
NC_010655.1|WP_012421089.1|2508221_2509376_-|acyltransferase	gnl|CDD|376607	pfam01757, Acyl_transf_3, Acyltransferase family. This family includes a range of acyltransferase enzymes. This domain is found in many as yet uncharacterized C. elegans proteins and it is approximately 300 amino acids long.	3.70377e-18
NC_010655.1|WP_012421084.1|2504129_2505764_-|head-tail-connector-protein	gnl|CDD|378829	pfam12236, Head-tail_con, Bacteriophage head to tail connecting protein. This family of head-tail connector proteins is found in bacteria and viruses. Proteins in this family are typically between 516 and 555 amino acids in length. This protein is found in Phage T7 and T3 among others.	2.76228e-156

Protein sequences

>NC_010655.1|WP_012421088.1|2507264_2507522_+|hypothetical-protein
MKNPLLSTEEKRRWLARVFRDEDGEYSQADKFKALVEDTKLAALQQEEEEFKRQREMGAAPQDPILDLLQSLPPAELNLNNHPSS
>NC_010655.1|WP_031931492.1|2506974_2507268_+|BlaI/MecI/CopY-family-transcriptional-regulator
MKALDFIQIFASNVRRLDFRLSSAQVILAVIAGYRRHSTITEATRLHPNTVTNILQDLIAQGYVNRIGDGRPYVYRPTADGEQLAGNLLDKNTFPGT
>NC_010655.1|WP_012421086.1|2506303_2506924_+|hypothetical-protein
MINESLLQPDTPSALDICNAALSKIGEAPLDALIANESTASRLCVLHYHPARRETLCMARWTFAATQTTLDSVSAQAPNSLTPYQFTLPADCLRVLDVECSEWKMQGRRIHASCAPLPLSYIADIENTDQFDPLFMDALATRLAEKLAMPLTGNQSLRQNLNQEFHKIILPQAATVNAVQCFSNDSHPLLDLLRKTKSPSCTEECE
>NC_010655.1|WP_143245884.1|2505772_2505979_-|hypothetical-protein
MKPSTPSASAPEQTIPVKAESVEQEVGEDYQARERQRQGMISTILARRHSSSGQGEVNPRTLLRKTLG
>NC_010655.1|WP_012421084.1|2504129_2505764_-|head-tail-connector-protein
MEERTAELNSVYKSLAAQRAPWETWWDRLRDYVLPRRLNREGEVSLPNRDAMDRMTDTTAVEACQKLASGHMSYITPSHDVWFKWSAPDDRGGDEAEAWYNQCSEIALKELSVSNFYTEIHECFLDRVALGTGSLFTGTSSDGRLLFTNIPCGQFACAENAEGRVDTYVREFTYTAHQARSMFGVKALGPKAREVLERGGNPYATTLRFLHVVRPRTRRSRRREQASHMPFESVYLSLDDQVIVEEGGYMEFPYLVTRFLKWGSGPYGLAPGRLVFPAIQQVQFLNRILDTLGEVAAFPRILELANQIGEVDLRAGGRTVITPEAASLHLPREWATQGKYDVGMDRLAQKQDAIRRAYYLPMLELWSGHRGNMTATEVMARENERVLMFSPSFTLFVSDLYSTMTRIFSLLFRMGKFPRPPRAVLRVGRDGSVAVGEPRVVYQSKIALVLRRLQSEGMDRSLQRLNMMMQAAPDLADHVDWDHCFRLSARVDGAPESMLRPWADVRAMRKEREDLQQGASLAPAEEDPYASLNPLLDQLTAIQK
>NC_010655.1|WP_012421083.1|2503851_2504133_-|hypothetical-protein
MNQDTTLQQEASVREARFKRRQLLRVFDTPDGRETLSFLEARFQTDLPVFQGSPGNYDPLDAMRRDAYREIFLYIRRQLQLAIKETTEEEKND
>NC_010655.1|WP_012421082.1|2502977_2503859_-|hypothetical-protein
MIDSIDNSMAAPFRDAVGSGAVSPETDALSETAVQTEPFPPLLGEDGGFAPDWYARFDELKGMEKSLSKFKTPEALAKSYAELERLRRYPGVENEEQMARFRRLAGLPESEEEYRLERPESTPESEWNAGLAERMARTAYRYGVPPEAMNALQETMAQAYDEAREHMEDARMEMEMQAEQSLQQEWGANYERNMGRAAAVLRRLASETGVDADALLDNPGLGSNPDAIRLLYQASRLLDEAPLHHTGNAAPSPAEEAMRMESDPSHPLYEAYMNVNHPNHKYANELYDRLTTR
>NC_010655.1|WP_012421081.1|2501804_2502308_-|thioredoxin-family-protein
MMNRHFIFALCTVLGFSVSGISMAQSVPTDKEAAAKAAKAAKVKFRWGKSLKSAQKQAEETGLPIVLLFTGTSWCGFCVKLEKEILSKKDFKQGMDGVAIGVKFEFGSSDFSKSKEAKTYNITGVPAMVVVDADGKELGRTGYVPGRTPAQYVEFFKKYAPKTAEGK
>NC_010655.1|WP_042448418.1|2501279_2501624_-|rubrerythrin
MPEFTNAFSGLKEDRKLTHDELVRAIRFMIAAEYESIQLYTQLAASIDDKLAQEVLWDISNEEKEHAGEFLRLLQVLAPDEQGFYDEGMGETNEKIDKLKASCPDGACSSSAAH
>NC_010655.1|WP_012421079.1|2500652_2500997_-|rubrerythrin
MPEFTNAFSGLKENRKLTHGELVRAIRFMIAAEYEAIQLYTQLAESIDHKLAQEVLLDISNEEKEHAGEFLRLLQVLAPDEQGFYDEGMGETNEKIDKLKASCPDGACSSSASH
>NC_010655.1|WP_012421089.1|2508221_2509376_-|acyltransferase
MNTNQSLNSRGGHIAWVDFLRILACFLVVLAHCCDPFVGSFDGSFNFKSAVFWGSLVRPCVPLFVMISGVLLFPVTLEMGAFYSRRLKRVLVPLIVWSLALPLLYFGYFAAGVQTASPNIVMDTYTWSATVGKLYTFFFNFNYDTTPLWYVYMLVGLYLFMPIMSAWLTQARRKDVKIFLGIWIFSMTLPYIQMLAPALGYEGNYGNMGILGVCDWNPYGMFYNFSGFLGYMVLAHYLTKYPLAWSWKKTLSITIPLFLIGFAVTFFGFLETQKHFPGQYSKLEVLWYFSGINVFLMTFAIFAVVSRLRIKAGPVLSKVAALTFGVYLCHFFFVQCSYDFVNFIGLGGLPSAVKIPLMACLASAVSAALVWLLSLNRWTRKSIM
>NC_010655.1|WP_012421090.1|2509840_2513422_-|bifunctional-proline-dehydrogenase/L-glutamate-gamma-semialdehyde-dehydrogenase
MTDSSIPDMMAEARRGQWTDQQLAAKAVELAESILKQSNAGMRGKEKRQAQQMERMMNDPAGKAFTLALADRVFRPSSPVRGAELFRYLLDGYGVPRYLSAADRFAIKMGGRFSAQFPGVVMPVITSQLRKESSNVILPAEDGKLRPHLRRRRKGGIRMNINQLGEAILGESEAHHRLQQVVDRLTDKDCDYISVKISAIFSQIHLVAFEETVKLIQERLRILYRAAITNAVTLPDGSRKPKFVNLDMEEYRDLHLTAEAFKRTLMEDEFMQLEAGIVLQAYLPDSWEEQMKLCAWAKERVEQGGARIKIRLVKGANLAMEKVEASMHGWAQAPYGTKAQVDANYKRMLHYGCMPDNARYVQFGVASHNLFDLCYAMLLREREGVRDQVEFEMLEGMANHQARVIRQAADGLLLYAPVVLKEDFHSAIAYLVRRLDENTSEENFLHDLFGMTPGSRSWEVQKKRFLKACQEKDEVKYGPNRTQNRAADPIQPSHYRDAFANERDTDWSLRQNAEWINGLIAAEKEKSGEEIPLVIDGEEITTNLWGVGRDPSRHNEVSYKFAYADFDQVEHALVTADRVRSSWASKSIGERAEILHRAAQELSRIRGEAIAAMVRDAGKAPTEADVEVSEAIDFCRYYAEGLDRDGMNDGVEMSPLGIICVMSPWNFPFAIPTGGVAAALMAGNAVVFKPSELAVYTAWQIVQAFWRAGVPKNVLQFVPMPRNEISCKFLMDPRLNGVIMTGSYRTGKMLRELRPDLHVLAETSGKDAMIITATADPDQAVKDLVKSAFGHSGQKCSAASVAIVEASVYDNPAFLRQLKDAAASLKVGGSWEVNSVVTPLIREPEGNLLRALTQLEPGEEWLLKPEPSEDNPCLWSPGIRLGVKPGSWFHQTECFGPVLGIIRAENLEEAIDIQNDSEFGLTGGLQSLDEREIALWKTKVQVGNAYINRVITGAIVRRQPFGGWNHSSMGPGAKAGGPNYLTMLGSWEEKALPQKLRTPGERISGLVEKLCSELPDCAKRIRSAAGSQAKWWMEEFGVDHDPSRVYGENNTFRYIPVKGILARVENMSDDDVAILLLGAKLCGVLLHLSIGTSRPWIQKMHGYYASLTVETEAELIGRMPEALPGIRFLRGTDISETLANAARARDVEVLDRPVLANGRLELLGYFREQSVSETVHRYGNLIPPPGSFKTDSV
>NC_010655.1|WP_012421091.1|2513580_2514576_-|hypothetical-protein
MDGSLFMRALAVIAFLALAFPGRAEMDALSVSCSAAPSLPSPVLVVYGSEEPGSAEARWLKALQPGTEERRALDEYVRDVQFVTVPRHPSVKDWEEDGSLSRAVMHGVRMLPSVVFLDSKGRVFDLVEGGASAASLREKVSLLAEKAQRVRPVTRVNDIPKGGDPAAEASAICRELEQVPPEAWFRDYPGTMKRLEKLNCTVPAFLNAREAALRLEKNRKTAELLGESFRASKASSIRTCLEAWRTCADDPSLSVEERQLILLSMVHPLWVRLEKVLYREAHTPESEDAFNQAVAVLEEVRDMNRSSVCGRRAHQLREELRRARLAAARYD
>NC_010655.1|WP_031931498.1|2514575_2515025_-|KH-domain-containing-protein
MTVQEIAEQSLKSLLASLGFSADIEVTETDGIVCLNISSPDSQYIIGGDGDRLDDLQYLVNRMIQRKMEDAPRVKVDCDHYRERNEARLLEKARSLAERVQESGKPMKMPPLNAYHRRLVHNALQSMEGIVTESEEGDSRYKRITIRKG
>NC_010655.1|WP_081429233.1|2515537_2517805_+|catalase-HPII
MNKPMKKKKPPMEDSAAPFPNGKEAAPHYTDTIDPELIKPTPKPTPPNAEPSAPGSMKMPDNATEKIRELDAMRSNGMGQALTSNLGVKISDDQNTLKAGSRGPSLLEDFHFLEKMAHFDQERIPERVVHARGSGAHGYFQVYKSLSKYTKAAFLQDPGEKTPVFVRFSTVQGFRGSPDTVRDIRGWATKFYTKEGNYDLVGNNTPVFFIQDAIKFPDFVHAVKPEPHNEMPQGQTAHDSFWDYVSLQPETLHNVMWAMSDRGIPRSFRTMEGFGIHTYKLVNEEGKSTFVRFHWKPVYGKKSLVWDEAQVLTGRDPDFHRKDLWQSIEAGDYPEYELGLQLIPEEDADQLDFDILDATKLIPEALVPVEIVGKMVLNRNPDNFFAETEQVAFCPANIVPGIDFSDDPLLQGRIFSYSDTQRHRLGGANFTEIPINRPICPFHNNQRDGFHRMQIDASPANYDPNSIGNNWPRETPPEKGGFTTSPQTVSGVKERLRNPSFAEYYSHPRLFWMSQTPVEQEHIINAFSFELGKVTRPYIRERVVDLLTRIDPDLASGVARNLGIQLTREQLSRELPRPVCGLEQDPSLSLYAHTDGNLKGLRVSLLAADGVSLKSVKEICEALHEEGIHPQIIAPHMGSVTTEEGEDLPVNGTLSGTPSVLFDSVIVPEGEQSIAALLKDGDAKYHLRQAYRHLKAIGLPGNAKAMLEAASLPQDMDDAGLLMPKDTKSLMPSFITAMKQHRVWSREPKTLDFGA
>NC_010655.1|WP_143245883.1|2518312_2521006_-|cytochrome-c-biogenesis-protein-CcsA
MQSALFLDYGRLTLMDRERTDAVWKKYGRSLWNFAGSYGLGIALMLILLVLTFAGTLHQVRLSSAMGSEAAIESFFGAAYVLIPLGGENSLISLPLPGMGITCVLLFANLLIGGVFRIRWTWRHAGVLVAHGGILLLLAGIMLGNKMTVAVEQVELPQGDRVHEYSLPFDLRLNRFVPEFYPGTSKPKSYESQITVFPESGGQYDAVIRMNEPLRLSGWTLYQMSWGQDSLHPGRLISILRASHNPLEQMPKWSSYIIAVGLLWHFACVFGRYLRRKPGLASAGTAATDELQAVSAPGGKKRLRLAGICLLVAAIFGIGMLAARPDVHPVLVEHYVPWSPFLVERAGAMAVQDGGRLKPVSTYAGFHLLRTLGKRSFVVDTPEGKRKLSPVEWMLDCMFRPELAEQYPVFLVNREEVVRRLHLPDQKDKRKKYSYAQLAERWEEMTRAVREIRLLGETNLTEAQKEILSLARNFDVMRGWMLVSRIMLENPAAMERMEFPRWFPSAGRDGERLWTASPDKAAGAFLAMASLLERKAIGMAGAEASALRMKAEGLLLEKLAQPNEAASAGERHSLEREIFYYRLDPLYVSLAVFVAAFVCLLLCALFRPAANAPLWRRFLRPGGFSLAWLTGAGGAGVLVAALVIRVLITMRSPVGNTYETIAFIACMGVLCALVVELFSKKGIVLAAGLLLGAFSCQMGILYESSQAVDHMDPLVAILRSNFLLSTHVITIVLGYAAGLLAAVLSHIYLLASPLRLIGGKTEQSLDRMAYGILCFSLVFTLVGTVFGGIWGNESWGRFWGWDPKENGALMIVLWQLTVLHARKAGWLSSWLLHFSNVVGGVIIAFAWWGVNMLGVGLHSYGFTSGRDALDMFYWSEAVLCVLFIILHYRALRRVDVR
>NC_010655.1|WP_012421095.1|2521054_2521630_-|rubrerythrin-family-protein
MKSIKGTETEKNLLKAFAGESEARNRYTYFAGVAKKAGYEQIAAIFLETADNEKEHAKVFFKLLKDACIEVTHAVCTAPLESTEDCLLAAAAGEHDEWSDMYPAFAEVADREGFPAIAETFRKIASVEQHHEARYLKLAENVREGRVFAKEKEIQWKCRNCGYVHTGSTAPKVCPACAHPQAFFEELADNF
>NC_010655.1|WP_012421097.1|2521931_2522528_+|GNAT-family-N-acetyltransferase
MNSANTPLLETERLILRKFTENDLEALFNIYSNEEVNTYLPWFPLTSLEEAAALFKEKYREVYKRPYGYHYAICPKNSNLPAGYIHAGTDDSHDLGYGLLQEFWHRGFATEATRAVVARLKKDGMPYITATHDIRNPRSGGVMKQLGMRYQYSYEELWQPKNIPVTFRLYQLNLDGQEDRVYQEYWNRSSVRFKETDI
>NC_010655.1|WP_143245882.1|2522602_2523232_-|hypothetical-protein
MRRIVSLPVLAAFVVLGASCSQQVQQPVKKAAPPPVYVGKVEQVYPNHHYVLIALAGNVYEPGTVLISQSPGREEKCRVANLIVTEERMGRARIPADIRSGAVEAGDLVFLYRNLAVPESTGKMDEQKPVSPEPETDEDSKVVAPPIAPDGGRMADGLMPLPGEQPVPASADQERISREREKILRELESVPDRLEEPWSGTFSGKPVER
>NC_010655.1|WP_012421099.1|2523251_2525708_-|DNA-translocase-FtsK
MVWGVVSLLGGAALLAAMLTFDVREIGWSYLNGSGQVIPGTSNVLGTVGLYGAGIFYWTLGGMAWMLVVLLEWWGLYRLLHYGRLPRSVVYGGLFLLLFGCLFLAAGHVPGNEWVARHQVQGAGGLVGHLLGTGLFFPLAGRSAVLAFSGLGYLLALVYAAGMRPRPFCRAMLREWRAWRMNRKEKRLARQTALLAREAARVRASMEDAALSAPRPVRKGRASVPRLQRTGDDLESLYHEAAAVAPSKPEDSVPPPSAPRTQGRLPLAPRPRITVAEPAEMKPAPKEQPFSKLSTPPTEEFREYELPPFELLHYEEKPEGPTAEDKEEMLEIQQKIIDTLTTFRVDVTPGDITRGPTITRYEVYPARGVRVNTFDQYAKDIALATKAESVNIVAPIPGKDTVGIEIVNRKKVAVPLRELLQDPAFCSPKKKIPLALGKDVYGRTVIGDLASMPHLLVAGATGSGKSVCINSIISSMLLKFRPDELRLILVDPKVVEMQPYSKLPHLIVPVVTDPKKVPNALRWCVNEMEHRYHCFAKVGVRNFEAFNKRPPDVPAQETEEPEDGQVDEALAESIARDLESQGEWPVEEDDELDLEDDGVIPERFPYIVIIIDELADLMQTVGADIETNIGRLTQKARAAGIHLIVATQTPRRQVVTGTIKANIPTRIAFQVASGTDSRVILDRQGAEKLVGKGDLLYLPPGSAQVERAQGAFISDDEVEALVAHCASQAKQKFHEEVQKSLDEPSRGGADSPLDDAEEECYAKCLEVAVVERKVSTSLLQRRLSIGYGRAARMMDLLESRGIIAPADNTNRPRKVLVE

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NC_010655_1	1.8|2438703|30|NC_010655|CRISPRCasFinder,CRT,PILER-CR	2438703-2438732	30	NZ_AP021899	Akkermansia muciniphila strain JCM 30893 plasmid pJ30893, complete sequence	7822-7851	2	0.933
NC_010655_1	1.10|2438834|30|NC_010655|CRISPRCasFinder,CRT,PILER-CR	2438834-2438863	30	NZ_AP021899	Akkermansia muciniphila strain JCM 30893 plasmid pJ30893, complete sequence	21780-21809	2	0.933
NC_010655_1	1.9|2438769|29|NC_010655|CRISPRCasFinder,CRT,PILER-CR	2438769-2438797	29	NC_021278	Mycobacteroides abscessus subsp. bolletii 50594 plasmid 1, complete sequence	93563-93591	5	0.828
NC_010655_1	1.10|2438834|30|NC_010655|CRISPRCasFinder,CRT,PILER-CR	2438834-2438863	30	NZ_CP029832	Azospirillum ramasamyi strain M2T2B2 plasmid unnamed2, complete sequence	149849-149878	7	0.767
NC_010655_1	1.11|2438900|30|NC_010655|CRISPRCasFinder,CRT,PILER-CR	2438900-2438929	30	NZ_CP032091	Pseudoalteromonas donghaensis strain HJ51 plasmid unnamed1, complete sequence	210509-210538	7	0.767
NC_010655_1	1.9|2438769|29|NC_010655|CRISPRCasFinder,CRT,PILER-CR	2438769-2438797	29	NZ_CP010326	Pantoea sp. PSNIH1 plasmid pPSP-3a9, complete sequence	232821-232849	8	0.724
NC_010655_1	1.10|2438834|30|NC_010655|CRISPRCasFinder,CRT,PILER-CR	2438834-2438863	30	MF150911	Ralstonia phage DU_RP_II, complete genome	36789-36818	8	0.733
NC_010655_2	2.1|2507621|35|NC_010655|CRISPRCasFinder	2507621-2507655	35	NZ_CP044330	Methylocystis rosea strain BRCS1 plasmid unnamed2, complete sequence	26699-26733	10	0.714
NC_010655_2	2.1|2507621|35|NC_010655|CRISPRCasFinder	2507621-2507655	35	NZ_CP034088	Methylocystis rosea strain GW6 plasmid pGW6_2, complete sequence	156976-157010	10	0.714
NC_010655_2	2.7|2507622|35|NC_010655|PILER-CR	2507622-2507656	35	NZ_CP044330	Methylocystis rosea strain BRCS1 plasmid unnamed2, complete sequence	26699-26733	10	0.714
NC_010655_2	2.7|2507622|35|NC_010655|PILER-CR	2507622-2507656	35	NZ_CP034088	Methylocystis rosea strain GW6 plasmid pGW6_2, complete sequence	156976-157010	10	0.714

1. spacer 1.8|2438703|30|NC_010655|CRISPRCasFinder,CRT,PILER-CR matches to NZ_AP021899 (Akkermansia muciniphila strain JCM 30893 plasmid pJ30893, complete sequence) position: , mismatch: 2, identity: 0.933

ggaggaaccttctacccctacggacctgct	CRISPR spacer
ggaggaaccttctacccctacggaccagca	Protospacer
************************** ** 

2. spacer 1.10|2438834|30|NC_010655|CRISPRCasFinder,CRT,PILER-CR matches to NZ_AP021899 (Akkermansia muciniphila strain JCM 30893 plasmid pJ30893, complete sequence) position: , mismatch: 2, identity: 0.933

gtagcgcaggtagagctgacggatgatcat	CRISPR spacer
gtagcgcaggtagagctgccggatgatcag	Protospacer
****************** ********** 

3. spacer 1.9|2438769|29|NC_010655|CRISPRCasFinder,CRT,PILER-CR matches to NC_021278 (Mycobacteroides abscessus subsp. bolletii 50594 plasmid 1, complete sequence) position: , mismatch: 5, identity: 0.828

ttgtggcgcagcatgcgccgcggccattg	CRISPR spacer
ctgtgccgcagcatgcgccgcggcgacgg	Protospacer
.**** ****************** *. *

4. spacer 1.10|2438834|30|NC_010655|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP029832 (Azospirillum ramasamyi strain M2T2B2 plasmid unnamed2, complete sequence) position: , mismatch: 7, identity: 0.767

gtagcgcaggtagagctgacggatgatcat	CRISPR spacer
atagcgcaggtagtgctggcggatgccgtt	Protospacer
.************ ****.****** .  *

5. spacer 1.11|2438900|30|NC_010655|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP032091 (Pseudoalteromonas donghaensis strain HJ51 plasmid unnamed1, complete sequence) position: , mismatch: 7, identity: 0.767

gactttgatgccgaaaataatgcttatcat	CRISPR spacer
tattttgatgccaaaaataatgcctattta	Protospacer
 *.*********.**********.***.  

6. spacer 1.9|2438769|29|NC_010655|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP010326 (Pantoea sp. PSNIH1 plasmid pPSP-3a9, complete sequence) position: , mismatch: 8, identity: 0.724

ttgtggcgcagcatgcgccgcggccattg	CRISPR spacer
ggctggcgcagcgtgcgccgctgccaggc	Protospacer
   *********.******** ****   

7. spacer 1.10|2438834|30|NC_010655|CRISPRCasFinder,CRT,PILER-CR matches to MF150911 (Ralstonia phage DU_RP_II, complete genome) position: , mismatch: 8, identity: 0.733

gtagcgcaggtagagctgacggatgatcat	CRISPR spacer
ctggcgccggtagagctgaccgatgaaatg	Protospacer
 *.**** ************ *****    

8. spacer 2.1|2507621|35|NC_010655|CRISPRCasFinder matches to NZ_CP044330 (Methylocystis rosea strain BRCS1 plasmid unnamed2, complete sequence) position: , mismatch: 10, identity: 0.714

ggatgttgtgacggccagacaagcaacgagcaata	CRISPR spacer
ggtcgttgtcacggccagacaagcgacgatggtct	Protospacer
** .***** **************.****  . . 

9. spacer 2.1|2507621|35|NC_010655|CRISPRCasFinder matches to NZ_CP034088 (Methylocystis rosea strain GW6 plasmid pGW6_2, complete sequence) position: , mismatch: 10, identity: 0.714

ggatgttgtgacggccagacaagcaacgagcaata	CRISPR spacer
ggtcgttgtcacggccagacaagcgacgatggtct	Protospacer
** .***** **************.****  . . 

10. spacer 2.7|2507622|35|NC_010655|PILER-CR matches to NZ_CP044330 (Methylocystis rosea strain BRCS1 plasmid unnamed2, complete sequence) position: , mismatch: 10, identity: 0.714

ggatgttgtgacggccagacaagcaacgagcaata	CRISPR spacer
ggtcgttgtcacggccagacaagcgacgatggtct	Protospacer
** .***** **************.****  . . 

11. spacer 2.7|2507622|35|NC_010655|PILER-CR matches to NZ_CP034088 (Methylocystis rosea strain GW6 plasmid pGW6_2, complete sequence) position: , mismatch: 10, identity: 0.714

ggatgttgtgacggccagacaagcaacgagcaata	CRISPR spacer
ggtcgttgtcacggccagacaagcgacgatggtct	Protospacer
** .***** **************.****  . .