CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NC_010803	Chlorobium limicola DSM 245, complete sequence	12 crisprs	WYL,cas6,cas8b2,cas7,cas5,cas3,cas1,cas2,cas4,csa3,cmr1gr7,cmr6gr7,cas10,cmr4gr7,cmr5gr11,cmr3gr5,DEDDh,csa5gr11	1	10	1	0

Results visualization

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CRISPR-Cas detection and classification

Crispr_ID: NC_010803_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_010803_1

277477-277615

Orphan

Consensus_repeat	Method
GAAGAGTGTGGGCGGTTGGCGGTG	CRISPRCasFinder

2 spacers

The CRISPR arrays of NC_010803_1

>merge|NC_010803|1|277477-277615|CRISPRCasFinder
GAAGAGTGTGGGCGGTTGGCGGTGGGCCGGTAGTCAGTAGTCGGTAGTCGGGGAAGAGTTGAAGAGTGTGGGCGGTTGGCGGTGTGCGGTGAGCGGAAAGAGTGTAAGAAAGTGAGATGAGTGTGAGCGGTGGGCCGTG

>NC_010803|1|1|277477-277615|CRISPRCasFinder
GAAGAGTGTGGGCGGTTGGCGGTG	GGCCGGTAGTCAGTAGTCGGTAGTCGGGGAAGAGTT
GAAGAGTGTGGGCGGTTGGCGGTG	TGCGGTGAGCGGAAAGAGTGTAAGAAAGTGA
GATGAGTGTGAGCGGTGGGCCGTG

Protein	Signature genes	Signature genes Name	Protein_function
NC_010803.1\|WP_012465224.1\|279788_280511_+\|hypothetical-protein	unknown	unknown	unknown
NC_010803.1\|WP_012465213.1\|263316_264564_+\|HipA-domain-containing-protein	unknown	unknown	gnl\|CDD\|377920
NC_010803.1\|WP_041465618.1\|274688_275357_+\|DedA-family-protein	unknown	unknown	gnl\|CDD\|182775
NC_010803.1\|WP_041465617.1\|271282_273547_-\|PBP1A-family-penicillin-binding-protein	unknown	unknown	gnl\|CDD\|273955
NC_010803.1\|WP_041465820.1\|281525_282107_-\|outer-membrane-beta-barrel-protein	unknown	unknown	gnl\|CDD\|379226
NC_010803.1\|WP_012465227.1\|282462_283272_+\|SDR-family-oxidoreductase	unknown	unknown	gnl\|CDD\|187576
NC_010803.1\|WP_012465222.1\|277729_278992_+\|putative-DNA-modification/repair-radical-SAM-protein	unknown	unknown	gnl\|CDD\|188431
NC_010803.1\|WP_041465822.1\|285184_285655_-\|hypothetical-protein	unknown	unknown	unknown
NC_010803.1\|WP_012465217.1\|269706_271248_-\|glutamine-hydrolyzing-GMP-synthase	unknown	unknown	gnl\|CDD\|234614
NC_010803.1\|WP_012465225.1\|280604_281447_-\|MBL-fold-metallo-hydrolase	unknown	unknown	gnl\|CDD\|293799
NC_010803.1\|WP_012465229.1\|284661_285195_+\|AAA-family-ATPase	unknown	unknown	gnl\|CDD\|226426
NC_010803.1\|WP_012465212.1\|262988_263324_+\|helix-turn-helix-transcriptional-regulator	unknown	unknown	gnl\|CDD\|238045
NC_010803.1\|WP_150081749.1\|283314_284655_+\|cobyrinate-a,c-diamide-synthase	unknown	unknown	gnl\|CDD\|234896
NC_010803.1\|WP_012465214.1\|264811_267580_+\|AAA-family-ATPase	unknown	unknown	gnl\|CDD\|224037
NC_010803.1\|WP_012465231.1\|285832_288382_+\|ATP-dependent-Clp-protease-ATP-binding-subunit	unknown	unknown	gnl\|CDD\|223616
NC_010803.1\|WP_012465219.1\|273602_274526_-\|alpha/beta-hydrolase	unknown	unknown	gnl\|CDD\|223669
NC_010803.1\|WP_012465223.1\|278996_279734_+\|TIGR03915-family-putative-DNA-repair-protein	unknown	unknown	gnl\|CDD\|274851
NC_010803.1\|WP_012465211.1\|262394_262820_+\|hypothetical-protein	unknown	unknown	unknown
NC_010803.1\|WP_012465216.1\|267974_269543_+\|transposase	unknown	unknown	gnl\|CDD\|227708
NC_010803.1\|WP_012465221.1\|276000_277476_+\|FAD-dependent-oxidoreductase	unknown	unknown	gnl\|CDD\|274272

Protein	Function_ID	Function_description	E-value
NC_010803.1\|WP_012465213.1\|263316_264564_+\|HipA-domain-containing-protein	gnl\|CDD\|377920	pfam07804, HipA_C, HipA-like C-terminal domain. The members of this family are similar to a region close to the C-terminus of the HipA protein expressed by various bacterial species. This protein is known to be involved in high-frequency persistence to the lethal effects of inhibition of either DNA or peptidoglycan synthesis. When expressed alone, it is toxic to bacterial cells, but it is usually tightly associated with HipB, and the HipA-HipB complex may be involved in autoregulation of the hip operon. The hip proteins may be involved in cell division control and may interact with cell division genes or their products.	2.20607e-55
NC_010803.1\|WP_041465618.1\|274688_275357_+\|DedA-family-protein	gnl\|CDD\|182775	PRK10847, PRK10847, DedA family protein.	1.06926e-96
NC_010803.1\|WP_041465617.1\|271282_273547_-\|PBP1A-family-penicillin-binding-protein	gnl\|CDD\|273955	TIGR02074, Includes:_Penicillin-insensitive_transglycosylase, penicillin-binding protein, 1A family. Bacterial that synthesize a cell wall of peptidoglycan (murein) generally have several transglycosylases and transpeptidases for the task. This family consists of bifunctional transglycosylase/transpeptidase penicillin-binding proteins (PBP). In the Proteobacteria, this family includes PBP 1A but not the paralogous PBP 1B (TIGR02071). This family also includes related proteins, often designated PBP 1A, from other bacterial lineages. [Cell envelope, Biosynthesis and degradation of murein sacculus and peptidoglycan].	0
NC_010803.1\|WP_041465820.1\|281525_282107_-\|outer-membrane-beta-barrel-protein	gnl\|CDD\|379226	pfam13505, OMP_b-brl, Outer membrane protein beta-barrel domain. This domain is found in a wide range of outer membrane proteins. This domain assumes a membrane bound beta-barrel fold.	1.70322e-11
NC_010803.1\|WP_012465227.1\|282462_283272_+\|SDR-family-oxidoreductase	gnl\|CDD\|187576	cd05266, SDR_a4, atypical (a) SDRs, subgroup 4. Atypical SDRs in this subgroup are poorly defined, one member is identified as a putative NAD-dependent epimerase/dehydratase. Atypical SDRs are distinct from classical SDRs. Members of this subgroup have a glycine-rich NAD(P)-binding motif that is related to, but is different from, the archetypical SDRs, GXGXXG. This subgroup also lacks most of the characteristic active site residues of the SDRs; however, the upstream Ser is present at the usual place, and some potential catalytic residues are present in place of the usual YXXXK active site motif. Atypical SDRs generally lack the catalytic residues characteristic of the SDRs, and their glycine-rich NAD(P)-binding motif is often different from the forms normally seen in classical or extended SDRs. Atypical SDRs include biliverdin IX beta reductase (BVR-B,aka flavin reductase), NMRa (a negative transcriptional regulator of various fungi), progesterone 5-beta-reductase like proteins, phenylcoumaran benzylic ether and pinoresinol-lariciresinol reductases, phenylpropene synthases, eugenol synthase, triphenylmethane reductase, isoflavone reductases, and others. SDRs are a functionally diverse family of oxidoreductases that have a single domain with a structurally conserved Rossmann fold, an NAD(P)(H)-binding region, and a structurally diverse C-terminal region. Sequence identity between different SDR enzymes is typically in the 15-30% range; they catalyze a wide range of activities including the metabolism of steroids, cofactors, carbohydrates, lipids, aromatic compounds, and amino acids, and act in redox sensing. Classical SDRs have an TGXXX[AG]XG cofactor binding motif and a YXXXK active site motif, with the Tyr residue of the active site motif serving as a critical catalytic residue (Tyr-151, human 15-hydroxyprostaglandin dehydrogenase numbering). In addition to the Tyr and Lys, there is often an upstream Ser and/or an Asn, contributing to the active site; while substrate binding is in the C-terminal region, which determines specificity. The standard reaction mechanism is a 4-pro-S hydride transfer and proton relay involving the conserved Tyr and Lys, a water molecule stabilized by Asn, and nicotinamide. In addition to the Rossmann fold core region typical of all SDRs, extended SDRs have a less conserved C-terminal extension of approximately 100 amino acids, and typically have a TGXXGXXG cofactor binding motif. Complex (multidomain) SDRs such as ketoreductase domains of fatty acid synthase have a GGXGXXG NAD(P)-binding motif and an altered active site motif (YXXXN). Fungal type ketoacyl reductases have a TGXXXGX(1-2)G NAD(P)-binding motif.	7.60353e-69
NC_010803.1\|WP_012465222.1\|277729_278992_+\|putative-DNA-modification/repair-radical-SAM-protein	gnl\|CDD\|188431	TIGR03916, hypothetical_protein, putative DNA modification/repair radical SAM protein. This uncharacterized protein of about 400 amino acids in length contains a radical SAM protein in the N-terminal half. Members are present in about twenty percent of prokaryotic genomes, always paired with a member of the conserved hypothetical protein TIGR03915. Roughly forty percent of the members of that family exist as fusions with a uracil-DNA glycosylase-like region, TIGR03914. In DNA, uracil results from deamidation of cytosine, forming U/G mismatches that lead to mutation, and so uracil-DNA glycosylase is a DNA repair enzyme. This indirect connection, and the recurring role or radical SAM protein in modification chemistries, suggest that this protein may act in DNA modification, repair, or both. [Unknown function, Enzymes of unknown specificity].	0
NC_010803.1\|WP_012465217.1\|269706_271248_-\|glutamine-hydrolyzing-GMP-synthase	gnl\|CDD\|234614	PRK00074, guaA, GMP synthase; Reviewed.	0
NC_010803.1\|WP_012465229.1\|284661_285195_+\|AAA-family-ATPase	gnl\|CDD\|226426	COG3911, COG3911, Predicted ATPase [General function prediction only].	1.19818e-46
NC_010803.1\|WP_012465212.1\|262988_263324_+\|helix-turn-helix-transcriptional-regulator	gnl\|CDD\|238045	cd00093, HTH_XRE, Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators.	9.59627e-05
NC_010803.1\|WP_150081749.1\|283314_284655_+\|cobyrinate-a,c-diamide-synthase	gnl\|CDD\|234896	PRK01077, PRK01077, cobyrinate a,c-diamide synthase.	1.38368e-175
NC_010803.1\|WP_012465214.1\|264811_267580_+\|AAA-family-ATPase	gnl\|CDD\|224037	COG1112, COG1112, Superfamily I DNA and RNA helicases and helicase subunits [DNA replication, recombination, and repair].	2.95798e-31
NC_010803.1\|WP_012465231.1\|285832_288382_+\|ATP-dependent-Clp-protease-ATP-binding-subunit	gnl\|CDD\|223616	COG0542, clpA, ATP-binding subunits of Clp protease and DnaK/DnaJ chaperones [Posttranslational modification, protein turnover, chaperones].	0
NC_010803.1\|WP_012465219.1\|273602_274526_-\|alpha/beta-hydrolase	gnl\|CDD\|223669	COG0596, MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) [General function prediction only].	3.32377e-20
NC_010803.1\|WP_012465223.1\|278996_279734_+\|TIGR03915-family-putative-DNA-repair-protein	gnl\|CDD\|274851	TIGR03915, putative_DNA_metabolism_protein, probable DNA metabolism protein. This model represents a conserved hypothetical protein that almost invariably pairs with an uncharacterized radical SAM protein. The pair occurs in about twenty percent of completed prokaryotic genomes. About forty percent of the members of this family occur as fusion proteins, where the C-terminal domain belongs to the uracil-DNA glycosylase family, a DNA repair family (because uracil in DNA is deamidated cytosine). The linkage by gene clustering and correlated species distribution to a radical SAM protein, and by gene fusion to a DNA repair protein family, suggests a role in DNA modification and/or repair.	1.00569e-94
NC_010803.1\|WP_012465225.1\|280604_281447_-\|MBL-fold-metallo-hydrolase	gnl\|CDD\|293799	cd07713, DHPS-like_MBL-fold, Methanocaldococcus jannaschii dihydropteroate synthase, Thermoanaerobacter tengcongensis Tflp, and related proteins; MBL-fold metallo hydrolase domain. This subgroup includes Methanocaldococcus jannaschii 7,8-dihydropterin-6-methyl-4-(beta-D-ribofuranosyl)-aminobenzene-5'-phosphate synthase (EC 2.5.1.15), a folate biosynthetic enzyme also known as dihydropteroate synthase and 7,8 dihydropteroate synthase. Thermoanaerobacter tengcongensis Tflp is a ferredoxin-like member. Members of this subgroup belong to the MBL-fold metallo-hydrolase superfamily which is comprised mainly of hydrolytic enzymes which carry out a variety of biological functions.	2.52145e-109
NC_010803.1\|WP_012465216.1\|267974_269543_+\|transposase	gnl\|CDD\|227708	COG5421, COG5421, Transposase [DNA replication, recombination, and repair].	5.02356e-25
NC_010803.1\|WP_012465221.1\|276000_277476_+\|FAD-dependent-oxidoreductase	gnl\|CDD\|274272	TIGR02733, similar_to_to_phytoene_dehydrogenase, C-3',4' desaturase CrtD. Members of this family are slr1293, a carotenoid biosynthesis protein which was shown to be the C-3',4' desaturase (CrtD) of myxoxanthophyll biosynthesis in Synechocystis sp. strain PCC 6803, and close homologs (presumed to be functionally equivalent) from other cyanobacteria, where myxoxanthophyll biosynthesis is either known or expected. This enzyme can act on neurosporene and so presumably catalyzes the first step that is committed to myxoxanthophyll. [Biosynthesis of cofactors, prosthetic groups, and carriers, Other].	2.97403e-72

>NC_010803.1|WP_012465221.1|276000_277476_+|FAD-dependent-oxidoreductase
MDFRELNIIVIGSGIGGLAAGAILAAKGAAVTVLEAQDYPGGCAATFFRNGYRFDAGATVGCGFHPGGPMYELGRELDINWPIEEEPVAWQYRHKELHLDLTRSGDAVLQRFPHSVSFWKEQKQLAGLLWQLASGGLSWPPETLRDLAGLLRKGVSGLSGAGRLLKFAPRTALAWLAAHQLDADQEFVRFIDAQLLISVQTTSAFAGAINAAIALDLPAAGAWHVKGGIGSIAELLAGSITDNGGAVLYRKKVIRIDSVRKQVVGVETGDGSAFAADMVLANLTPESLAELLDSHSADPAVKKGPTAEWSAFMLYLGMDPSVFEASGTHHLQIIGSSGELGEGNSIFVSVSPPAESGRAPAGLCAVTVSTHSRPGPWFEALNRGGGEYLELKRAYTENVLDLMSSQFPGVRGAIRFIDAATPVTWQRYTGRSRGYVGGYPQISLFDVISPSTAFDNMFLVGDSVFPGQSLPGVVTGARRVVEMVLKSAGRM
>NC_010803.1|WP_041465618.1|274688_275357_+|DedA-family-protein
MDNSFTDILFTLADFIMHIDKHLLVLASEYGLWLYGILFVIIFCETGLVVTPFLPGDSLLFAAGSLASVPGSTLDEHLLFLVFFVAAVLGDSVNYSIGHKLGPKVFDFRKSRFFNPEHLEKTRAFFEKYGGKTIIIARFIPIIRTFAPFVAGIGAMAYPKFIFFNILGALLWVGLFCYSGYFFGQLPFVQENFKLLILGIIIFSLLPPVFEYFKHRRGKAEA
>NC_010803.1|WP_012465219.1|273602_274526_-|alpha/beta-hydrolase
MSYLASSRCRLYYEDSAEHNPALQDKPAVLFVNGWAISSRYWKPLVDLLTPDFRCITYDQSGTGRTLIKGHKPSFTIEGFAAEAGELIEHLGLHHSRNLHIVGHSMGGMVATELCIQYREALLSATITACGIFEETAFTSLGLLFLGGLIDVSMQLRNVFQVEPLRSLFIKRAAAKEIGKKYSDIIIEDFTLSDRDATNAVGKFSIDPEALRAYTRHVIAIASPVLCCVGMEDHTIPPEGTISLFEKRKSVSSAPTSLARFMSLGHLPMLEDTPGYGGILKKHFDFAEQFYKKTPGEIEPCEQYLIP
>NC_010803.1|WP_041465617.1|271282_273547_-|PBP1A-family-penicillin-binding-protein
MKNLFLKKLFFSLIALLFISLTTAMSAFALNPFKGLPSLEELENPNPELASLVYSEDGILLHKFFLKNRTFIPLKSIPKSAQHALIATEDVSFYSHWGIDLRRLALVMGENLIKGRKRWHGASTITQQLAKNLYLTQERTISRKAKEFITAIELEKTYTKDEILALYLNTVYFGSGAYGIEAASRTYFGKPASQLTLPESATLIATLKNPTGYNPVKNPSSSIGRRNLILSLMEKEKFITPAQAAAAKKTRLILKFTPVNHHGLAPYFTEYIRQTIKPASMLGDINVYRDGLSIQTTLDSRMQKYAEQAVREHLSSLQAAFDRSWRWPESLKNQIIKESARFKELREDGLTEQSAMAKLKADRVWLNNLLKEKTRIQVGFVVIDPSNGHVKAWVGGNNFSPDDYRYQFDHVWQAKRQPGSTFKPFVYTAAIDKGIPANFRVLNQPVALRSGSGIWSPRNSDGSSGGLTTLRSALSRSMNQVTVRLAYEQLKVPEIISYARRMGISSPIPSNLSIVLGTAEVTPLELAGAFATYANNGIWNEPVSILKVEDKHNRVISEYRPNSRFAIDSTSNFVMVSMLKDVVNKGTGIALRARYGFDYEAAGKTGTTQSMRDAWFAGFTPQLAAVVWTGFDDERVKFTSMEYGQGARAALPIWALFMKSAYSDPTLKLENRYFHIPDNVIAVPIAGNTNTPSDLMGSDVYIEYYTPKGFNYYKSQPVRSYQSTTEESDDASGSGESAEPQPPPSEESAGEGIF
>NC_010803.1|WP_012465217.1|269706_271248_-|glutamine-hydrolyzing-GMP-synthase
MQSVLVLDFGSQYTQLIARRIRELGIYSEILPYNTTPETIREHAPKAIILSGGPTSVYGESAILPHEGIFSLGLPILGICYGLQAIAKHFGGEVASSAKQEFGRAKMLVSRDGEPESMLFRNIPDSDVWMSHGDKVVNLPDGFRITASSANSEMCALETYGSKGALKVFGLQFHPEVQHTLYGKQLLSNFLIDIAGITPDWSPKHFIDHQIEEIRRTAGDETVICGISGGVDSSVAAVLVSRAIGKNLHCVFVDNGLLRKNEADKVMQFLKHLGLRLTLADASELFLKRLKNVASPEKKRKIIGRTFIQVFEEQLDKEKFLVQGTLYPDVIESVSVKGPSETIKSHHNVGGLPKRMKLKLIEPLRELFKDEVRAVGRELGIAEDILMRHPFPGPGLAVRVLGSVSKERLDILRDADEIFLEELKSSGLYQKVWQAFSVLLPVQSVGVMGDKRTYENVLALRAVESSDGMTADWAQLPHDFLARVSNRIINEVRGINRVAYDISSKPPATIEWE
>NC_010803.1|WP_012465216.1|267974_269543_+|transposase
MAYRVHQLNKKTGVTYVYEAVSTWDKTLKQARNKQICVGKIDPVTGEFVPSKRLDPAQSALRDPAVTASAQVMGPTFVLDAIALRTGVSALMKSVFPQSHQELMAMAFYLTSQGGALSLCASWAKGHMPDLAASLGSQRMSDLLASIGTDRKQAFFAKWMKMRLENDYLCYDITSVSSYSELNEYIKYGYNRDEEKLPQLNLAMLFGQKSGLPGYYHRIPGNINDVSTLHNLLETFRMLEIGQLHYVMDKGFYSKKNVDDLVGYRDHFTISVPINNRWLQRAIDDIHQTIHGPEGYRRLDDEILYVHSRFYPWGEARRRCYLHLYYNATKRAREIDTFNESLFRYREELESGKPIAAHQKAYEDFFTVKTTPKRGTIVSFNTEAINRHISRYAGFQALLSSDIKDPVEALRVYRNKDSVEKCFDDLKNTLDMKRLRMHSSATVDGRLFIQFIALILISALRKQMRDSGLIEQYTVRELLREMETLTKITYSGKYGHILTELTKPQRQILTALNIPVLDPASL
>NC_010803.1|WP_012465214.1|264811_267580_+|AAA-family-ATPase
MSIDSRQNLIIIKGKDRTDQILRIEEADECMVVTFSNGKPYFYAREKVAWLSNPGLITTEHCRVMVEGDVLFDIEEVLRFETWVKIFRRNGVSRCCLFSDFSVQRMTLSDGRSSDVLAYFRELAEVSALRTNEDKSLIAMKYRHLNIVSGRSILASFLQARPPGSGTVPSDLIFPFGCNMSQKTAVQRAIEHPVSLIQGPPGTGKTQTILNLIGNMLLWRKRVAVVSSNNSATANVLEKLQKYELDFVAASLGSTRNKQVFIEGQSSDAVSMPILQADHEASVLQEISLLNKELDKAFEKKNELAAIIQQIDALRLEMDHFETFCEETKGDDLTVMDRSIQAKLSARKLLHAWLASEKELKRHAKAGLPSPSKRRVGFLKKMGFLLRFGMEGRAYFELSVEARIPLLQKAYYLRKLTDMENRRKTLEELLGGFRFDEHLERLRELSMQLLKHRLAELYNNRERRVFALEDLRNQPGEFLNEYPLILSTTFSIITSLKSGYLFDCVIVDEASQVDLLSGVLAMGCAEKLVIVGDPMQLPNVLTKQDEQQAKEIALRYDLPDYARFERHNLLSAVRTAFPDIPETLLQEHYRCHPKIIQFCNQKFYGGELLVMTRDQGEPDVLKAYMTVEGRHARGTFNQRQVDEVTQNVLPELASIQPADIGIVSPFRAQAARMQSSVGSNEIEIDTVHKYQGREKRAIIITTVSNEANEFVDNPNLLNVAVSRAQERLRLVVSREMAEGNGNVADLVRYIRYNNCEVIPGRVRSVFDLLYHDYTEARLAVLKKRIRVSKYDSENLVHSEIEAVLQERAYRGFGVVFQFPLSMLVRDTGNLTTEESAYANHPWTKTDFVVFRKVDKSPVLVIEVDGYAFHREGTRQAERDALKDAVLSKCGLPILRLSTVGSNERNRISKKLEEVTTGKNRHV
>NC_010803.1|WP_012465213.1|263316_264564_+|HipA-domain-containing-protein
MPEVEVYIDWQGSCRLIGRLYRQSGRGRETVSFRYDDRWIAAADHFPIDVSLKVGRGIFVPPAGREMFGTLGDSAPDQWGRRLMRRAERRRAEKELRAPRTLFETDFLLGVADETRLGAFRFRYPGDAGFLSSTESGVPKLVELGKLLGVTERILRDEESDEDLLMIFAPGSSLGGARPKASVIDQYGQLSIAKFPKENDEYSIETWEEISLTLAAKAGIRTPVHELKRIAGKAILLSRRFDRKDGGRIPFMSAMSMTGSLDGEGGSYLDIVDALGEFGAQARTDRAELFRRMVFNVLISNVDDHLRNHGFLMTSRHGWVLSPVFDLNPTPQDVKPRVLSTAIDLEDGTCSIGLVRDVAHFFGLQKAEADRMISDVAHVTETWSEVAKTVGARPSEIKRMESAFEHDDLYRALRL
>NC_010803.1|WP_012465212.1|262988_263324_+|helix-turn-helix-transcriptional-regulator
MPTSHLPNSAVRKALRKLGANIHEARMRRRLPMSVVAERASTSRPTLSRLEKGDPSVSIGIYAAVLQALGLLDDLALLADPARDSVGQQLSTAALPRRARISGRKRSDGDA
>NC_010803.1|WP_012465211.1|262394_262820_+|hypothetical-protein
MLKTIQAGLAYFAIVLGTGFLLGVVRVPFLVPRIGERWAELAEMPIMAAVIYFAAGFILRRFPEVGSPGKSLIVGFLALALSVAAEVALATVLQDRTLAEFIASRDKVSGSVYLALLLVFAVMPRLHFSRRARNASRHSGA
>NC_010803.1|WP_012465222.1|277729_278992_+|putative-DNA-modification/repair-radical-SAM-protein
MEILDKLQILSGAARYDASCASSGSRREGSSSGIGNTSQGGICHSWADDGRCISLLKILLSNDCIYDCAYCVNRATNPVPRASFSAREVVELTMEFYRRNYIEGLFLSSAVMQSPDQTMERMVGVAELLRTEERFGGYIHLKIIPGSSSALVRKAGLYADRISVNIELPSSESLKRLAPQKQKQAILEPMSLIGRQIQESLVERKASRRAPRFAPAGQSTQMIIGASPESDFQILKLSQGLYRKMNLKRVYYSAFVPVNEDNRLPVLASPPLLREHRLYQADWLLRFYGFSAEEILSDDAPNLDETFDPKTSWALRHPEFFPVEINRADYAVLLRVPGIGVTSARRIVAARRFSVITPEGLKKIGVVMKRAKYFITCSGRPFEKIDRQPAMLQSSLLLGDGGDTAVKKPPKQLVLPGIFT
>NC_010803.1|WP_012465223.1|278996_279734_+|TIGR03915-family-putative-DNA-repair-protein
MSRYLYDGTAEGLLSAAARIIAEVSDPEKATLVERENTLFEDGVFIGTDAVAAETLFNRLRQEAPDAAHTLYYFILSEKEGMETSLLHYISLALRFGNRVNGNLADSAVRDIVTVSRKAQRELHRMKGLVRFEKLRDGAYLARMEPDHNILQPLAGHFSRRLRAEDWFIYDVRRRTAARWHSGTLQLGTIEQFTAPALSDEEKEVQALWQIFFRTIAIPDRKNSRLQKSNMPMKYWKYLTEKQGE
>NC_010803.1|WP_012465224.1|279788_280511_+|hypothetical-protein
MNLTETAEKAIEAYGGCSLWQNAGTLETEVSAYGLAFTLKRRPFFRHARIVEEVHRPFSVLTPIGRNPGVTGILDGHSVRLEDENGRVIAERRSARDYFRIGRRLLWWDDLDMSYFANYASWNYFTLPALLMNEEIAWRELEPGLLEARFPDGIPTHSSVQRFRFERESGRLLQHDYTAEIISPLARASNVVLQHARNSAGLLYPSVRRVTPRGPKGRPLARPVLIHLDIHEYRLTGNGS
>NC_010803.1|WP_012465225.1|280604_281447_-|MBL-fold-metallo-hydrolase
MSANNLSLTILSDNNAAECCTAEHGFSALIETGTCAILFDTGRENVLLPNAKALGVDLSTVRQLVLSHGHYDHTGGIGDLLTLAPEATVYLHPGAFRERFSIRNGIPKPVSMPEPALIALNSLPEKQINLIEQPSVLTSRSGITGPVPRITSYEDTGGPFFLDPEGSIPDAIDDDLSIWFETREGLVLVAGCCHAGIINTLRYVTELTGTERIAALIGGFHLSTASPERLMQTVDELNTFDIGRIIPCHCTGEAAAAYFRRNLHCHVEPGYAGMRLEFPL
>NC_010803.1|WP_041465820.1|281525_282107_-|outer-membrane-beta-barrel-protein
MKIWRSALAGALLMIGSTATACAATPYVSGSVGIAMMEDSDVQFSGIDDGSITYDAGMAATLAAGLDMGYTRIEGEVGYQENGIEESDDVEVAITTFMVNGYYDFELPASPIKPYISAGIGVADVNAEELSLGDDSSLVLAGQLGAGVGFAVAPALTLDARYRYLMTTEAEFNGDTDISIGSHNVMLGLRLGL
>NC_010803.1|WP_012465227.1|282462_283272_+|SDR-family-oxidoreductase
MQKESISILGCGWLGLPLAGSLIKEGYSVKGSTTSEGKLDLLREAGIEPFLVTLDPEIDGEEFCDFLQSDILVVNIPPSRREDIVEFHIQQISSLIDALGQSPVRSVLFVSSTSVYPMLNREVTEEDAVDPESPSGQALLHVEEMLMQETGFQTTVLRFGGLTGYDRSPEKYLSRMSGITALDQPVNLTHRDDCVNIIMEIIRLQQWGEIFNACSPMHPLKRDFYARAAETAGIPLPPAISASEPSPFKLVSSRKLESALSYTFMHSGS
>NC_010803.1|WP_150081749.1|283314_284655_+|cobyrinate-a,c-diamide-synthase
MHKAFLIAAPSSGSGKTTLTLALLRILARRGYRVQPFKCGPDYLDTRLHTLAASYKERKSSGINLDTFMASEAHARTLFGRYGSRADVSVVEGVMGLFDGAEKAQGSSAEIAKLLDLPVIMVVNAKSMAYSAAPLLHGFRTFDPEVKMLGVIFNQVNTPTHYRYLEAAALDAGVEPLGYVPQSEGIAISERHLGLNTSPGYDREAVIEAMADHVEKTVSVNRLLDLSRVVLPPSVSEPCGRVVPSADRKVIAVARDEAFNFLYEENLAVLKEHGEVVFFSPMEDGHLPESHLLYLAGGYPELYADRLAANQAMRHSIAAYCFRGGAAYAECGGMMYLGRSLSAADGTVHPMCGVLDLDTTMQEARLTLGYRKVSLDGLYPHELRGHEFHYSRIDRLGTLQNIAAVANARDEGCTTALFRIRNTFASYVHLYWGERRDFPDFLMARS
>NC_010803.1|WP_012465229.1|284661_285195_+|AAA-family-ATPase
MTGRYIITGGPGSGKSTLLEALHHEGYRCYREVSRELIREQLSRPEGVLPWQNLPAFARLAFDAMKRQHEHAKGRDGICFFDRGIPDVFGYLEASGYPLETEYLEAHAKCSYSKTVFVLPPWPEIFVNDRERPQTYRQSVVLYHALCKVYERLGYERCEVPKTSVRDRAAFLLSFIK
>NC_010803.1|WP_041465822.1|285184_285655_-|hypothetical-protein
MNVHHILIDDLNPEHRELSIYRTGSVNRIRLQDSIYKVYASLEIDAHNYAALFHYRIIEACSALPFISQTGNGLDSWDEAFLHNSRLNELTTLIADASATIDRQKNETILLGWHDQPVAVAYLRSIDPARTANFLERLLLFIQESEREGCDLEFIL
>NC_010803.1|WP_012465231.1|285832_288382_+|ATP-dependent-Clp-protease-ATP-binding-subunit
MEGNFSNRVQDVIRLSREEALRLGHDYIGTEHLLLGLIREGEGIAARILRNLKIDLLRLKQKIEESTHPKVPATQMGNVPLTKQAEKVLKITYLEAKICKSNVIGTEHLLLSILKGDDNIAAQILEQFGVTYDLVKDELISITTGKSESDEPPMEGSYSSGSAERLPKKGDPKRGERTKTPVLDNFGRDITRLALEDKLDPIIGREKEIERVAQVLSRRKKNNPVLIGEPGVGKTAIAEGLALKIVQRKVSRVLYDKRVVALDLAALVAGTKYRGQFEERMKALMNELERSRDVILFIDELHTIVGAGGASGSLDASNIFKPALARGELQCIGATTLDEYRQYIEKDGALDRRFQKIMVEPASVDETIQILNNIKSKYESHHHVQYSEDAIEKAVKLSERYITDRFLPDKAIDVMDEAGARVHLSNIHVPVEILDLEKSIEEIKAEKNQVVKMQNFEEAATLRDKEKHLLEALDHAKQEWEERASESVYDVTEEDITSVIAMMTGIPVVKVAQSESRKLLSMEADLMKEVIGQDEAIKKITKAIQRTRAGLKDPSRPIGSFIFLGPTGVGKTELAKALTRYIFDSEDALIRADMSEYMEKFSVSRLVGAPPGYVGYEEGGQLTEKVRRKPYSVVLIDEIEKAHPDVFNILLQVLDEGVLTDGLGRKVDFRNTIIIMTSNIGAKDIKNIGAGTGMGFSPPDDIAGTYKNMKSTIEDALKRVFNPEFLNRIDDIVVFHQLEKQHIFKIIDITAGKLFKRLREMGIDVEIDEKAKEFLVDKGYDQKYGARPLKRALQKYVEDPLAEEMLRGRFTEGSLIRITFDEVEKELHFAEGHEKEHTGTVEITPPEDK

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Crispr_ID: NC_010803_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_010803_2

499776-508012

Unclear

I-A,II-B,III-A

Consensus_repeat	Method
CTTATAATTGCACCAATATGGAATTGAAAC	PILER-CR
CTTATAATTGCACCAATATGGAATTGAAAC	CRISPRCasFinder
CTTATAATTGCACCAATATGGAATTGAAAC	CRT

123 spacers

cas4,cas2,cas1,cas3,cas5,cas7,cas8b2,cas6

The CRISPR arrays of NC_010803_2

>merge|NC_010803|2|499776-508012|PILER-CR,CRISPRCasFinder,CRT
CTTATAATTGCACCAATATGGAATTGAAACCAGTGATAATATCTAATTCCTTCGCCGTATTCTTTTCCTTATAATTGCACCAATATGGAATTGAAACACGTTCTTGATATGCGAATACGTTACCATCGTTGGCCTTATAATTGCACCAATATGGAATTGAAACCAGGGCAACCTTTCCGCAATCGGTACATTTACCGCTCCTTATAATTGCACCAATATGGAATTGAAACTAAAAACGTAACCTCTCCGATGCAGGTTATGCGAGGACTTATAATTGCACCAATATGGAATTGAAACCTATCTTCACTGTGGTGAATACGGTGATAAAACTGCTTATAATTGCACCAATATGGAATTGAAACTACGGATGGTACAACATCTTTCGGTCTGGAATCTAACTTATAATTGCACCAATATGGAATTGAAACTTAAAGAACGAACAGCTCGCGTTATGCCTCTCTACTCCTTATAATTGCACCAATATGGAATTGAAACACGCTAGAATTAGTAATCGGCTGAGTACCTCCTGTATTACTTATAATTGCACCAATATGGAATTGAAACAGATTTGTAGTTCCCTCGGTGAGACCAAGAGCTTTACTTATAATTGCACCAATATGGAATTGAAACTTACCGCCCATAGCCGACAGTACTGGATTTAGACCTCTTATAATTGCACCAATATGGAATTGAAACTATAAAGAACGCCTTAGTAATGTCTTATTAGGTGCTCTTATAATTGCACCAATATGGAATTGAAACTAGCAATTGCTAAAGTATTTGAAGCCTCTTGTAAGGCTTATAATTGCACCAATATGGAATTGAAACTGTAATCGTTCCCGGCAAGCATTGCCTTTACACCGCTTATAATTGCACCAATATGGAATTGAAACGTCGTTTCGGGTGAGTTCAGTGATCTCCTCGACCCCTTATAATTGCACCAATATGGAATTGAAACGAGACCGCAAACATCAGCAGCATGTAGGCTGGATTGCTTATAATTGCACCAATATGGAATTGAAACATATAGGCTTGATCGGTGTTGCAAGCCGCCCAAATCCCTTATAATTGCACCAATATGGAATTGAAACCAGGGTATCTGAATCGGCATATCGGAATAAGCTTCTCTTATAATTGCACCAATATGGAATTGAAACTTATTGATTCAACAACCTCATCAACCTTTTCCGGAGCTTATAATTGCACCAATATGGAATTGAAACGCGACATCGCAACGCAGGCCCTTGTCGACGGGCTCCTTATAATTGCACCAATATGGAATTGAAACTCAAGAACAACAGCGTTACCGGAGACAGATCGTGTGTCTTATAATTGCACCAATATGGAATTGAAACCAGTGCGGGCATGGCACAAAGTTCCGGCGCTGGTCCTTATAATTGCACCAATATGGAATTGAAACTTGAGTAGGCCTCCGCGATATCGAGCGTCGGGAGTACTTATAATTGCACCAATATGGAATTGAAACTTGCACTCCGTGACGGGTAAGCCCGTCTGATTCCGCTTATAATTGCACCAATATGGAATTGAAACTTGAAAGCTGATCCGCATAGTCTGCGAGCTGTGATGCTTATAATTGCACCAATATGGAATTGAAACCTTGCTATTTGTTGCAGGGTTGGCAAGGTTCGTCACAGCTTATAATTGCACCAATATGGAATTGAAACTCGTTCATCTCATGCACCAGCCCCGCAAGCGAAACCCCTTATAATTGCACCAATATGGAATTGAAACGCATTACAGCAACACGTCCCTGTCTGTCTATTGCGGACTTATAATTGCACCAATATGGAATTGAAACTTAAGTTGCGTCCTTCCGCCTGAGCCGTCTTGATGACTTATAATTGCACCAATATGGAATTGAAACCATTGAGAGCATTGACGCACACGTACGCGGCATTCAGCTTATAATTGCACCAATATGGAATTGAAACCAGCAATCGTCGATAAGCGAGTGATGATCTTACTGTTCCTTATAATTGCACCAATATGGAATTGAAACACAGATTCGCCGAGTCCAGCGCAGCAAGCGCCGCCTCTTATAATTGCACCAATATGGAATTGAAACCCCGGAAGGCCAAGTCCATCCAGATACGCCTGTTCAACTTATAATTGCACCAATATGGAATTGAAACTGAGCTTGCTCAAACGCTCGGCATCGCCGTCATGGTGCTTATAATTGCACCAATATGGAATTGAAACGGATGAGCCATCGATGTTTCCCGATACGCATTCCGACTTATAATTGCACCAATATGGAATTGAAACGCGCATCAACACCGCCCTTAAAGAGAGCCTCACCGCTTATAATTGCACCAATATGGAATTGAAACGCTGCAGGAAGTCAAAACAAAATTCCCGTTCTGGGAACTTATAATTGCACCAATATGGAATTGAAACGTTTTTCGAGTGGAAGATAAGCCAGGGGAGGACTGAACTTATAATTGCACCAATATGGAATTGAAACATTCGCTCCGCATGTCTGATGACGCTCCGGTAAATCTCTTATAATTGCACCAATATGGAATTGAAACAAAAGCGTATTCCCGACAATGGCGATTTTCCCTTCCGACTTATAATTGCACCAATATGGAATTGAAACGGGTAGCTATCTATTATTTCGTCAATGAGCCATAGCGTCTTATAATTGCACCAATATGGAATTGAAACTTCTTCCACGGAATAGCGTTGTAGCCACCCTTTCGCAACTTATAATTGCACCAATATGGAATTGAAACTTGCGGAACTGCGCCGCCGTGGCGTCTGTGTCCTCTACTTATAATTGCACCAATATGGAATTGAAACTGGAGTAACGAGAAATGCCTCAATCGTCATGATTCCCCTTATAATTGCACCAATATGGAATTGAAACGCATGCGTACCAAGTCCAACTCTGCAAGCAAACGAACTTATAATTGCACCAATATGGAATTGAAACGCATCAACGGGGAGCAGACAGTGAAGAGGTTAAACGCTTATAATTGCACCAATATGGAATTGAAACCTCGTACTTCTCGACTATCGCAAGCTGCTCTCTGCATCTTATAATTGCACCAATATGGAATTGAAACCGACAAAGCGTGGAATCAGACCATTGAGGATCATGTCTTATAATTGCACCAATATGGAATTGAAACCAATCAAACATGCAAGTAATTAATAACATCCTGTACAGCTTATAATTGCACCAATATGGAATTGAAACAATTAAAGTTCACAAAAGAGCTGCTGCGCTACTTCAACTTATAATTGCACCAATATGGAATTGAAACCAGTGCAGGAGGTCATTAATCCTTACATTGTGGTTACTTATAATTGCACCAATATGGAATTGAAACGTATTTAATGCCACTGAGGAACTGCATGGTATTCCGTCTTATAATTGCACCAATATGGAATTGAAACTAATCATGTTATAGCAAATGTTGACGGTTTGCAAGATGCTTATAATTGCACCAATATGGAATTGAAACTCTGTATCAATCCCCATTGCATGCTTTCGTGCCAGCCCTTATAATTGCACCAATATGGAATTGAAACAGGCTTATTTGCTGCGGGCGGAACGAAACGCTCTTGACTTATAATTGCACCAATATGGAATTGAAACGCGTTTTTGATGTTCGAGGCAATATGGTGCATATCGAACTTATAATTGCACCAATATGGAATTGAAACTGTAAGCGCATTGTCGACGCGGTTCATGAGCATCCCGGCTTATAATTGCACCAATATGGAATTGAAACTCCATCCGGAGTTTTCCATTTCTTTGCCTTCGGATTCTTATAATTGCACCAATATGGAATTGAAACTAAGAGGATCAGCGCCCATGCGCTGAGCCATATTCACTTATAATTGCACCAATATGGAATTGAAACTCGGGTGTCACCCTCACAGCTACTTGAGCCAGCTTCTTATAATTGCACCAATATGGAATTGAAACGCAGCGTAAGAGGTCGTCGCCGACCACTCCGCGTAGCTTATAATTGCACCAATATGGAATTGAAACGTGTCAGTCGTGCCCATTACATCAAGTTTCGTGGGCCTTATAATTGCACCAATATGGAATTGAAACGTTGTCGTCGGTAGAGTGATCTCTGTACCGGACGCATCCTTATAATTGCACCAATATGGAATTGAAACATCTCAAAAACTGATATAGTCGCTGCAGCATCAGCACCTTATAATTGCACCAATATGGAATTGAAACCAAAAGGATTCTATCTCGGATGCGGAGGGAGTTCCCTTATAATTGCACCAATATGGAATTGAAACGCGTTCATGTTTTTAAGAACAGCACCTTCATAACCTCTTATAATTGCACCAATATGGAATTGAAACTACTCTTGCGTTATCACCGTAAACGCCACCGTTCGGTATTGCTTATAATTGCACCAATATGGAATTGAAACTTTTTGAACAGTCTTTTTACTTCGCTTCCGAAGCGATCTTATAATTGCACCAATATGGAATTGAAACACGTCTGAGGATTTTCGTAACCCATAATCGTGCTTTGCTTATAATTGCACCAATATGGAATTGAAACTCGCAACAAGCTGCTTGCGGAAAGCGGTGCTGAACTCCGCTTATAATTGCACCAATATGGAATTGAAACGTCGATTGAGCCGTTATGCTCGATTCCGTCCAGAAGGCTTATAATTGCACCAATATGGAATTGAAACAGCTCTTGAATCTGGTCTTTAAGCAGCTTGTGTACAGAGCTTATAATTGCACCAATATGGAATTGAAACGCCGAAAGGCCCGACTCAGCAGAAATGCTACGAAATGGCTTATAATTGCACCAATATGGAATTGAAACTGCAAGCGCCTCCTGCTCGTTGCCGCTGCCGCTGAACTTATAATTGCACCAATATGGAATTGAAACCCGAAAGTGGCGGAGAAGGACATGAAGGCCATGAACTTATAATTGCACCAATATGGAATTGAAACTCCGACAGCGGGCCTCCACCCTGCGACAAACCAGTTCTTATAATTGCACCAATATGGAATTGAAACTTCGCTATCGATCGTGGAATATCCCTCACGATCGGGCTTATAATTGCACCAATATGGAATTGAAACTCCGAAGCATCACGCTGTCCGGATCGGCGAACGTTGCTTATAATTGCACCAATATGGAATTGAAACTTACCTATTTCGGTAGGTATCTCGGTTTCCGGATCGTTCTTCTTATAATTGCACCAATATGGAATTGAAACTAAGTGTTGGCGCGGAATTGTTTTATTTAAAAAGATCCTTATAATTGCACCAATATGGAATTGAAACAGAGAATATATATTGAATTTGTGAGTCAAGTCAAACCTTATAATTGCACCAATATGGAATTGAAACCCGGATTAATGTTTATAACCGATGAACCACCGCCGCTTATAATTGCACCAATATGGAATTGAAACTATACCGGAGACGTAGGGAGATGTATGTACGGTGCAACTTATAATTGCACCAATATGGAATTGAAACAAAACACCCGCCTACGCAGGAATCCACGACACCCTGCTTATAATTGCACCAATATGGAATTGAAACTCGCAGCTGTCATATCGAGATAGGCGTGGCCTGTCTCCTTATAATTGCACCAATATGGAATTGAAACGTCTGGCCCGCGCCGTTCACCTCTGCCGCTGAGCCACCTTATAATTGTACCAATATGGAATTGAAACAAATAAACAAGCGCTATCGCCAGTTTTTTTTAAACCACTTATAATTGCACCAATATGGAATTGAAACTAGTAAAAATTTGATGGGTTCGGGTACGCCAGATGCACTTATAATTGCACCAATATGGAATTGAAACTCGAAGGCCGCAGGCAGCTCTTCAAAGCCCTGCCCCGCTTATAATTGCACCAATATGGAATTGAAACTCAAGAATATGTGAACGATACAATTTCGTTCCTTTTCCTTATAATTGCACCAATATGGAATTGAAACCTTGTACTGCGTAACATAGCCGTAGTAGGCTTTGGAGTTCTTATAATTGCACCAATATGGAATTGAAACGATAGAGGTGTTGTCGCTTCCGCTTCCGCCTGCTTTCTTATAATTGCACCAATATGGAATTGAAACAACACTGGCTGTAATCGGTCAGATACCCCGCTGTCCCGCTTATAATTGCACCAATATGGAATTGAAACTCAGCAAATACGCGGCAAAACGCCGAGACATCACCGCTTATAATTGCACCAATATGGAATTGAAACGCATGCGCAGCTGGGGAGCCGTAGCCATCAGCACCGACTTATAATTGCACCAATATGGAATTGAAACATGATCAAGACCGGAGAGCACAAGGTTACCAAGATGCTTATAATTGCACCAATATGGAATTGAAACTAAAAGTAGAAGTAGAAGTAGAAGTAGAAGTAAATGCTTATAATTGCACCAATATGGAATTGAAACGATATTTAGAGTTGCAGATACTGTCGCCCCATCTCCCTTATAATTGCACCAATATGGAATTGAAACGAAAAGAACACCGTTACTGGCAGCGCATGTGCAATTCTTATAATTGCACCAATATGGAATTGAAACTGAGCTACAAGCATCCTGATCAGCCTACAAGCACTCCTTATAATTGCACCAATATGGAATTGAAACGACACGGTTATACATGAAAGGATCGGCACGTAGCTGGCTTATAATTGCACCAATATGGAATTGAAACGCAAATCATTGCAAGCTGTGAGGACAGCATCGATCTCTTATAATTGCACCAATATGGAATTGAAACCTTATCGTCACCATGCAATTCTTTATGATTTCTTTTCTCTTATAATTGCACCAATATGGAATTGAAACGCGATAGACGCCTGTACCTGTATTTCGAGTATCTTCCTTATAATTGCACCAATATGGAATTGAAACGGTGAATTGCCGCCAGTAGCATTTTCAGAAATCGTACAACTTATAATTGCACCAATATGGAATTGAAACGCGATAGACGCCTGTACCTGTATTTCGAGTATCTTTCTTATAATTGCACCAATATGGAATTGAAACAAAGCCCTGCAGGGATACCTTCCCGAAACGTCCTGACTTATAATTGCACCAATATGGAATTGAAACCCGTAATGGCCGCGTTGTCTGCCGGCGCATTGCTTACTTATAATTGCACCAATATGGAATTGAAACCGATGATTGATAAGGTTTATGTAGATGCTCAACAAGCTTATAATTGCACCAATATGGAATTGAAACTTGTGCCGCATATCGTTTTACCGACTCCAGCAAAACGTCTTATAATTGCACCAATATGGAATTGAAACAAATATTCCGTACCCCTCAAGGCCGAGCTGATCCATCTTATAATTGCACCAATATGGAATTGAAACATGCAAGACATCTCTTGATCTCGTTCGTTTATTCGCTCCTTATAATTGCACCAATATGGAATTGAAACACTGATTTTTCGATCTCGGCCATAGGCGTCTTGAACTTATAATTGCACCAATATGGAATTGAAACACCGTACCATAGCCACAACAGGCTTCGACACCAGCGCCTTATAATTGCACCAATATGGAATTGAAACTGAACCAGCTCATCCGCTGGATCCTCGAACTCAACCGCTTATAATTGCACCAATATGGAATTGAAACCCGGAAACTCTTTATCATATCTCCTCCATGTCAAGCACTTATAATTGCACCAATATGGAATTGAAACGCCTTCCTTGGCCACAAAAAGGTCAGGAAGTATCCATCTTATAATTGCACCAATATGGAATTGAAACTAAAAGTAGAAGTAGAAGTAGAAGTAGAAGTAAATGCTTATAATTGCACCAATATGGAATTGAAACAGAATTTTCATTCGGTGTTTGAAATAAATCTCAACAACTTATAATTGCACCAATATGGAATTGAAACGAGGACGGTTATTGTCCCTGTGACATCGATAGTGCTGCTTATAATTGCACCAATATGGAATTGAAACTCAGGCTCATGATGTAATCCATCGCCCATCATTTCGCTTATAATTGCACCAATATGGAATTGAAACTCGATCCGGCATTCCCGGATGATGAAGCGCCGTTTTACTTATAATTGCACCAATATGGAATTGAAACCATGGACAGGTTGCAAGGTTGGACTGGTTTCCGGTTTGCTTATAATTGCACCAATATGGAATTGAAACCCTTTTTGGCGGCTCCGAACGATCGAATCGGTTGCCCGCTTATAATAGCACCAATATGGAATTGAAAC

>NC_010803|2|1|499776-508012|PILER-CR
CTTATAATTGCACCAATATGGAATTGAAAC	CAGTGATAATATCTAATTCCTTCGCCGTATTCTTTTC
CTTATAATTGCACCAATATGGAATTGAAAC	ACGTTCTTGATATGCGAATACGTTACCATCGTTGGC
CTTATAATTGCACCAATATGGAATTGAAAC	CAGGGCAACCTTTCCGCAATCGGTACATTTACCGCTC
CTTATAATTGCACCAATATGGAATTGAAAC	TAAAAACGTAACCTCTCCGATGCAGGTTATGCGAGGA
CTTATAATTGCACCAATATGGAATTGAAAC	CTATCTTCACTGTGGTGAATACGGTGATAAAACTG
CTTATAATTGCACCAATATGGAATTGAAAC	TACGGATGGTACAACATCTTTCGGTCTGGAATCTAA
CTTATAATTGCACCAATATGGAATTGAAAC	TTAAAGAACGAACAGCTCGCGTTATGCCTCTCTACTC
CTTATAATTGCACCAATATGGAATTGAAAC	ACGCTAGAATTAGTAATCGGCTGAGTACCTCCTGTATTA
CTTATAATTGCACCAATATGGAATTGAAAC	AGATTTGTAGTTCCCTCGGTGAGACCAAGAGCTTTA
CTTATAATTGCACCAATATGGAATTGAAAC	TTACCGCCCATAGCCGACAGTACTGGATTTAGACCT
CTTATAATTGCACCAATATGGAATTGAAAC	TATAAAGAACGCCTTAGTAATGTCTTATTAGGTGCT
CTTATAATTGCACCAATATGGAATTGAAAC	TAGCAATTGCTAAAGTATTTGAAGCCTCTTGTAAGG
CTTATAATTGCACCAATATGGAATTGAAAC	TGTAATCGTTCCCGGCAAGCATTGCCTTTACACCG
CTTATAATTGCACCAATATGGAATTGAAAC	GTCGTTTCGGGTGAGTTCAGTGATCTCCTCGACCC
CTTATAATTGCACCAATATGGAATTGAAAC	GAGACCGCAAACATCAGCAGCATGTAGGCTGGATTG
CTTATAATTGCACCAATATGGAATTGAAAC	ATATAGGCTTGATCGGTGTTGCAAGCCGCCCAAATCC
CTTATAATTGCACCAATATGGAATTGAAAC	CAGGGTATCTGAATCGGCATATCGGAATAAGCTTCT
CTTATAATTGCACCAATATGGAATTGAAAC	TTATTGATTCAACAACCTCATCAACCTTTTCCGGAG
CTTATAATTGCACCAATATGGAATTGAAAC	GCGACATCGCAACGCAGGCCCTTGTCGACGGGCTC
CTTATAATTGCACCAATATGGAATTGAAAC	TCAAGAACAACAGCGTTACCGGAGACAGATCGTGTGT
CTTATAATTGCACCAATATGGAATTGAAAC	CAGTGCGGGCATGGCACAAAGTTCCGGCGCTGGTC
CTTATAATTGCACCAATATGGAATTGAAAC	TTGAGTAGGCCTCCGCGATATCGAGCGTCGGGAGTA
CTTATAATTGCACCAATATGGAATTGAAAC	TTGCACTCCGTGACGGGTAAGCCCGTCTGATTCCG
CTTATAATTGCACCAATATGGAATTGAAAC	TTGAAAGCTGATCCGCATAGTCTGCGAGCTGTGATG
CTTATAATTGCACCAATATGGAATTGAAAC	CTTGCTATTTGTTGCAGGGTTGGCAAGGTTCGTCACAG
CTTATAATTGCACCAATATGGAATTGAAAC	TCGTTCATCTCATGCACCAGCCCCGCAAGCGAAACCC
CTTATAATTGCACCAATATGGAATTGAAAC	GCATTACAGCAACACGTCCCTGTCTGTCTATTGCGGA
CTTATAATTGCACCAATATGGAATTGAAAC	TTAAGTTGCGTCCTTCCGCCTGAGCCGTCTTGATGA
CTTATAATTGCACCAATATGGAATTGAAAC	CATTGAGAGCATTGACGCACACGTACGCGGCATTCAG
CTTATAATTGCACCAATATGGAATTGAAAC	CAGCAATCGTCGATAAGCGAGTGATGATCTTACTGTTC
CTTATAATTGCACCAATATGGAATTGAAAC	ACAGATTCGCCGAGTCCAGCGCAGCAAGCGCCGCCT
CTTATAATTGCACCAATATGGAATTGAAAC	CCCGGAAGGCCAAGTCCATCCAGATACGCCTGTTCAA
CTTATAATTGCACCAATATGGAATTGAAAC	TGAGCTTGCTCAAACGCTCGGCATCGCCGTCATGGTG
CTTATAATTGCACCAATATGGAATTGAAAC	GGATGAGCCATCGATGTTTCCCGATACGCATTCCGA
CTTATAATTGCACCAATATGGAATTGAAAC	GCGCATCAACACCGCCCTTAAAGAGAGCCTCACCG
CTTATAATTGCACCAATATGGAATTGAAAC	GCTGCAGGAAGTCAAAACAAAATTCCCGTTCTGGGAA
CTTATAATTGCACCAATATGGAATTGAAAC	GTTTTTCGAGTGGAAGATAAGCCAGGGGAGGACTGAA
CTTATAATTGCACCAATATGGAATTGAAAC	ATTCGCTCCGCATGTCTGATGACGCTCCGGTAAATCT
CTTATAATTGCACCAATATGGAATTGAAAC	AAAAGCGTATTCCCGACAATGGCGATTTTCCCTTCCGA
CTTATAATTGCACCAATATGGAATTGAAAC	GGGTAGCTATCTATTATTTCGTCAATGAGCCATAGCGT
CTTATAATTGCACCAATATGGAATTGAAAC	TTCTTCCACGGAATAGCGTTGTAGCCACCCTTTCGCAA
CTTATAATTGCACCAATATGGAATTGAAAC	TTGCGGAACTGCGCCGCCGTGGCGTCTGTGTCCTCTA
CTTATAATTGCACCAATATGGAATTGAAAC	TGGAGTAACGAGAAATGCCTCAATCGTCATGATTCCC
CTTATAATTGCACCAATATGGAATTGAAAC	GCATGCGTACCAAGTCCAACTCTGCAAGCAAACGAA
CTTATAATTGCACCAATATGGAATTGAAAC	GCATCAACGGGGAGCAGACAGTGAAGAGGTTAAACG
CTTATAATTGCACCAATATGGAATTGAAAC	CTCGTACTTCTCGACTATCGCAAGCTGCTCTCTGCAT
CTTATAATTGCACCAATATGGAATTGAAAC	CGACAAAGCGTGGAATCAGACCATTGAGGATCATGT
CTTATAATTGCACCAATATGGAATTGAAAC	CAATCAAACATGCAAGTAATTAATAACATCCTGTACAG
CTTATAATTGCACCAATATGGAATTGAAAC	AATTAAAGTTCACAAAAGAGCTGCTGCGCTACTTCAA
CTTATAATTGCACCAATATGGAATTGAAAC	CAGTGCAGGAGGTCATTAATCCTTACATTGTGGTTA
CTTATAATTGCACCAATATGGAATTGAAAC	GTATTTAATGCCACTGAGGAACTGCATGGTATTCCGT
CTTATAATTGCACCAATATGGAATTGAAAC	TAATCATGTTATAGCAAATGTTGACGGTTTGCAAGATG
CTTATAATTGCACCAATATGGAATTGAAAC	TCTGTATCAATCCCCATTGCATGCTTTCGTGCCAGCC
CTTATAATTGCACCAATATGGAATTGAAAC	AGGCTTATTTGCTGCGGGCGGAACGAAACGCTCTTGA
CTTATAATTGCACCAATATGGAATTGAAAC	GCGTTTTTGATGTTCGAGGCAATATGGTGCATATCGAA
CTTATAATTGCACCAATATGGAATTGAAAC	TGTAAGCGCATTGTCGACGCGGTTCATGAGCATCCCGG
CTTATAATTGCACCAATATGGAATTGAAAC	TCCATCCGGAGTTTTCCATTTCTTTGCCTTCGGATT
CTTATAATTGCACCAATATGGAATTGAAAC	TAAGAGGATCAGCGCCCATGCGCTGAGCCATATTCA
CTTATAATTGCACCAATATGGAATTGAAAC	TCGGGTGTCACCCTCACAGCTACTTGAGCCAGCTT
CTTATAATTGCACCAATATGGAATTGAAAC	GCAGCGTAAGAGGTCGTCGCCGACCACTCCGCGTAG
CTTATAATTGCACCAATATGGAATTGAAAC	GTGTCAGTCGTGCCCATTACATCAAGTTTCGTGGGC
CTTATAATTGCACCAATATGGAATTGAAAC	GTTGTCGTCGGTAGAGTGATCTCTGTACCGGACGCATC
CTTATAATTGCACCAATATGGAATTGAAAC	ATCTCAAAAACTGATATAGTCGCTGCAGCATCAGCAC
CTTATAATTGCACCAATATGGAATTGAAAC	CAAAAGGATTCTATCTCGGATGCGGAGGGAGTTCC
CTTATAATTGCACCAATATGGAATTGAAAC	GCGTTCATGTTTTTAAGAACAGCACCTTCATAACCT
CTTATAATTGCACCAATATGGAATTGAAAC	TACTCTTGCGTTATCACCGTAAACGCCACCGTTCGGTATTG
CTTATAATTGCACCAATATGGAATTGAAAC	TTTTTGAACAGTCTTTTTACTTCGCTTCCGAAGCGAT
CTTATAATTGCACCAATATGGAATTGAAAC	ACGTCTGAGGATTTTCGTAACCCATAATCGTGCTTTG
CTTATAATTGCACCAATATGGAATTGAAAC	TCGCAACAAGCTGCTTGCGGAAAGCGGTGCTGAACTCCG
CTTATAATTGCACCAATATGGAATTGAAAC	GTCGATTGAGCCGTTATGCTCGATTCCGTCCAGAAGG
CTTATAATTGCACCAATATGGAATTGAAAC	AGCTCTTGAATCTGGTCTTTAAGCAGCTTGTGTACAGAG
CTTATAATTGCACCAATATGGAATTGAAAC	GCCGAAAGGCCCGACTCAGCAGAAATGCTACGAAATGG
CTTATAATTGCACCAATATGGAATTGAAAC	TGCAAGCGCCTCCTGCTCGTTGCCGCTGCCGCTGAA
CTTATAATTGCACCAATATGGAATTGAAAC	CCGAAAGTGGCGGAGAAGGACATGAAGGCCATGAA
CTTATAATTGCACCAATATGGAATTGAAAC	TCCGACAGCGGGCCTCCACCCTGCGACAAACCAGTT
CTTATAATTGCACCAATATGGAATTGAAAC	TTCGCTATCGATCGTGGAATATCCCTCACGATCGGG
CTTATAATTGCACCAATATGGAATTGAAAC	TCCGAAGCATCACGCTGTCCGGATCGGCGAACGTTG
CTTATAATTGCACCAATATGGAATTGAAAC	TTACCTATTTCGGTAGGTATCTCGGTTTCCGGATCGTTCTT
CTTATAATTGCACCAATATGGAATTGAAAC	TAAGTGTTGGCGCGGAATTGTTTTATTTAAAAAGATC
CTTATAATTGCACCAATATGGAATTGAAAC	AGAGAATATATATTGAATTTGTGAGTCAAGTCAAAC
CTTATAATTGCACCAATATGGAATTGAAAC	CCGGATTAATGTTTATAACCGATGAACCACCGCCG
CTTATAATTGCACCAATATGGAATTGAAAC	TATACCGGAGACGTAGGGAGATGTATGTACGGTGCAA
CTTATAATTGCACCAATATGGAATTGAAAC	AAAACACCCGCCTACGCAGGAATCCACGACACCCTG
CTTATAATTGCACCAATATGGAATTGAAAC	TCGCAGCTGTCATATCGAGATAGGCGTGGCCTGTCTC
CTTATAATTGCACCAATATGGAATTGAAAC	GTCTGGCCCGCGCCGTTCACCTCTGCCGCTGAGCCAC
CTTATAATTGTACCAATATGGAATTGAAAC	AAATAAACAAGCGCTATCGCCAGTTTTTTTTAAACCA
CTTATAATTGCACCAATATGGAATTGAAAC	TAGTAAAAATTTGATGGGTTCGGGTACGCCAGATGCA
CTTATAATTGCACCAATATGGAATTGAAAC	TCGAAGGCCGCAGGCAGCTCTTCAAAGCCCTGCCCCG
CTTATAATTGCACCAATATGGAATTGAAAC	TCAAGAATATGTGAACGATACAATTTCGTTCCTTTTC
CTTATAATTGCACCAATATGGAATTGAAAC	CTTGTACTGCGTAACATAGCCGTAGTAGGCTTTGGAGTT
CTTATAATTGCACCAATATGGAATTGAAAC	GATAGAGGTGTTGTCGCTTCCGCTTCCGCCTGCTTT
CTTATAATTGCACCAATATGGAATTGAAAC	AACACTGGCTGTAATCGGTCAGATACCCCGCTGTCCCG
CTTATAATTGCACCAATATGGAATTGAAAC	TCAGCAAATACGCGGCAAAACGCCGAGACATCACCG
CTTATAATTGCACCAATATGGAATTGAAAC	GCATGCGCAGCTGGGGAGCCGTAGCCATCAGCACCGA
CTTATAATTGCACCAATATGGAATTGAAAC	ATGATCAAGACCGGAGAGCACAAGGTTACCAAGATG
CTTATAATTGCACCAATATGGAATTGAAAC	TAAAAGTAGAAGTAGAAGTAGAAGTAGAAGTAAATG
CTTATAATTGCACCAATATGGAATTGAAAC	GATATTTAGAGTTGCAGATACTGTCGCCCCATCTCC
CTTATAATTGCACCAATATGGAATTGAAAC	GAAAAGAACACCGTTACTGGCAGCGCATGTGCAATT
CTTATAATTGCACCAATATGGAATTGAAAC	TGAGCTACAAGCATCCTGATCAGCCTACAAGCACTC
CTTATAATTGCACCAATATGGAATTGAAAC	GACACGGTTATACATGAAAGGATCGGCACGTAGCTGG
CTTATAATTGCACCAATATGGAATTGAAAC	GCAAATCATTGCAAGCTGTGAGGACAGCATCGATCT
CTTATAATTGCACCAATATGGAATTGAAAC	CTTATCGTCACCATGCAATTCTTTATGATTTCTTTTCT
CTTATAATTGCACCAATATGGAATTGAAAC	GCGATAGACGCCTGTACCTGTATTTCGAGTATCTTC
CTTATAATTGCACCAATATGGAATTGAAAC	GGTGAATTGCCGCCAGTAGCATTTTCAGAAATCGTACAA
CTTATAATTGCACCAATATGGAATTGAAAC	GCGATAGACGCCTGTACCTGTATTTCGAGTATCTTT
CTTATAATTGCACCAATATGGAATTGAAAC	AAAGCCCTGCAGGGATACCTTCCCGAAACGTCCTGA
CTTATAATTGCACCAATATGGAATTGAAAC	CCGTAATGGCCGCGTTGTCTGCCGGCGCATTGCTTA
CTTATAATTGCACCAATATGGAATTGAAAC	CGATGATTGATAAGGTTTATGTAGATGCTCAACAAG
CTTATAATTGCACCAATATGGAATTGAAAC	TTGTGCCGCATATCGTTTTACCGACTCCAGCAAAACGT
CTTATAATTGCACCAATATGGAATTGAAAC	AAATATTCCGTACCCCTCAAGGCCGAGCTGATCCAT
CTTATAATTGCACCAATATGGAATTGAAAC	ATGCAAGACATCTCTTGATCTCGTTCGTTTATTCGCTC
CTTATAATTGCACCAATATGGAATTGAAAC	ACTGATTTTTCGATCTCGGCCATAGGCGTCTTGAA
CTTATAATTGCACCAATATGGAATTGAAAC	ACCGTACCATAGCCACAACAGGCTTCGACACCAGCGC
CTTATAATTGCACCAATATGGAATTGAAAC	TGAACCAGCTCATCCGCTGGATCCTCGAACTCAACCG
CTTATAATTGCACCAATATGGAATTGAAAC	CCGGAAACTCTTTATCATATCTCCTCCATGTCAAGCA
CTTATAATTGCACCAATATGGAATTGAAAC	GCCTTCCTTGGCCACAAAAAGGTCAGGAAGTATCCAT
CTTATAATTGCACCAATATGGAATTGAAAC	TAAAAGTAGAAGTAGAAGTAGAAGTAGAAGTAAATG
CTTATAATTGCACCAATATGGAATTGAAAC	AGAATTTTCATTCGGTGTTTGAAATAAATCTCAACAA
CTTATAATTGCACCAATATGGAATTGAAAC	GAGGACGGTTATTGTCCCTGTGACATCGATAGTGCTG
CTTATAATTGCACCAATATGGAATTGAAAC	TCAGGCTCATGATGTAATCCATCGCCCATCATTTCG
CTTATAATTGCACCAATATGGAATTGAAAC	TCGATCCGGCATTCCCGGATGATGAAGCGCCGTTTTA
CTTATAATTGCACCAATATGGAATTGAAAC	CATGGACAGGTTGCAAGGTTGGACTGGTTTCCGGTTTG
CTTATAATTGCACCAATATGGAATTGAAAC	CCTTTTTGGCGGCTCCGAACGATCGAATCGGTTGCCCG
CTTATAATAGCACCAATATGGAATTGAAAC

>NC_010803|2|2|499776-508012|CRISPRCasFinder
CTTATAATTGCACCAATATGGAATTGAAAC	CAGTGATAATATCTAATTCCTTCGCCGTATTCTTTTC
CTTATAATTGCACCAATATGGAATTGAAAC	ACGTTCTTGATATGCGAATACGTTACCATCGTTGGC
CTTATAATTGCACCAATATGGAATTGAAAC	CAGGGCAACCTTTCCGCAATCGGTACATTTACCGCTC
CTTATAATTGCACCAATATGGAATTGAAAC	TAAAAACGTAACCTCTCCGATGCAGGTTATGCGAGGA
CTTATAATTGCACCAATATGGAATTGAAAC	CTATCTTCACTGTGGTGAATACGGTGATAAAACTG
CTTATAATTGCACCAATATGGAATTGAAAC	TACGGATGGTACAACATCTTTCGGTCTGGAATCTAA
CTTATAATTGCACCAATATGGAATTGAAAC	TTAAAGAACGAACAGCTCGCGTTATGCCTCTCTACTC
CTTATAATTGCACCAATATGGAATTGAAAC	ACGCTAGAATTAGTAATCGGCTGAGTACCTCCTGTATTA
CTTATAATTGCACCAATATGGAATTGAAAC	AGATTTGTAGTTCCCTCGGTGAGACCAAGAGCTTTA
CTTATAATTGCACCAATATGGAATTGAAAC	TTACCGCCCATAGCCGACAGTACTGGATTTAGACCT
CTTATAATTGCACCAATATGGAATTGAAAC	TATAAAGAACGCCTTAGTAATGTCTTATTAGGTGCT
CTTATAATTGCACCAATATGGAATTGAAAC	TAGCAATTGCTAAAGTATTTGAAGCCTCTTGTAAGG
CTTATAATTGCACCAATATGGAATTGAAAC	TGTAATCGTTCCCGGCAAGCATTGCCTTTACACCG
CTTATAATTGCACCAATATGGAATTGAAAC	GTCGTTTCGGGTGAGTTCAGTGATCTCCTCGACCC
CTTATAATTGCACCAATATGGAATTGAAAC	GAGACCGCAAACATCAGCAGCATGTAGGCTGGATTG
CTTATAATTGCACCAATATGGAATTGAAAC	ATATAGGCTTGATCGGTGTTGCAAGCCGCCCAAATCC
CTTATAATTGCACCAATATGGAATTGAAAC	CAGGGTATCTGAATCGGCATATCGGAATAAGCTTCT
CTTATAATTGCACCAATATGGAATTGAAAC	TTATTGATTCAACAACCTCATCAACCTTTTCCGGAG
CTTATAATTGCACCAATATGGAATTGAAAC	GCGACATCGCAACGCAGGCCCTTGTCGACGGGCTC
CTTATAATTGCACCAATATGGAATTGAAAC	TCAAGAACAACAGCGTTACCGGAGACAGATCGTGTGT
CTTATAATTGCACCAATATGGAATTGAAAC	CAGTGCGGGCATGGCACAAAGTTCCGGCGCTGGTC
CTTATAATTGCACCAATATGGAATTGAAAC	TTGAGTAGGCCTCCGCGATATCGAGCGTCGGGAGTA
CTTATAATTGCACCAATATGGAATTGAAAC	TTGCACTCCGTGACGGGTAAGCCCGTCTGATTCCG
CTTATAATTGCACCAATATGGAATTGAAAC	TTGAAAGCTGATCCGCATAGTCTGCGAGCTGTGATG
CTTATAATTGCACCAATATGGAATTGAAAC	CTTGCTATTTGTTGCAGGGTTGGCAAGGTTCGTCACAG
CTTATAATTGCACCAATATGGAATTGAAAC	TCGTTCATCTCATGCACCAGCCCCGCAAGCGAAACCC
CTTATAATTGCACCAATATGGAATTGAAAC	GCATTACAGCAACACGTCCCTGTCTGTCTATTGCGGA
CTTATAATTGCACCAATATGGAATTGAAAC	TTAAGTTGCGTCCTTCCGCCTGAGCCGTCTTGATGA
CTTATAATTGCACCAATATGGAATTGAAAC	CATTGAGAGCATTGACGCACACGTACGCGGCATTCAG
CTTATAATTGCACCAATATGGAATTGAAAC	CAGCAATCGTCGATAAGCGAGTGATGATCTTACTGTTC
CTTATAATTGCACCAATATGGAATTGAAAC	ACAGATTCGCCGAGTCCAGCGCAGCAAGCGCCGCCT
CTTATAATTGCACCAATATGGAATTGAAAC	CCCGGAAGGCCAAGTCCATCCAGATACGCCTGTTCAA
CTTATAATTGCACCAATATGGAATTGAAAC	TGAGCTTGCTCAAACGCTCGGCATCGCCGTCATGGTG
CTTATAATTGCACCAATATGGAATTGAAAC	GGATGAGCCATCGATGTTTCCCGATACGCATTCCGA
CTTATAATTGCACCAATATGGAATTGAAAC	GCGCATCAACACCGCCCTTAAAGAGAGCCTCACCG
CTTATAATTGCACCAATATGGAATTGAAAC	GCTGCAGGAAGTCAAAACAAAATTCCCGTTCTGGGAA
CTTATAATTGCACCAATATGGAATTGAAAC	GTTTTTCGAGTGGAAGATAAGCCAGGGGAGGACTGAA
CTTATAATTGCACCAATATGGAATTGAAAC	ATTCGCTCCGCATGTCTGATGACGCTCCGGTAAATCT
CTTATAATTGCACCAATATGGAATTGAAAC	AAAAGCGTATTCCCGACAATGGCGATTTTCCCTTCCGA
CTTATAATTGCACCAATATGGAATTGAAAC	GGGTAGCTATCTATTATTTCGTCAATGAGCCATAGCGT
CTTATAATTGCACCAATATGGAATTGAAAC	TTCTTCCACGGAATAGCGTTGTAGCCACCCTTTCGCAA
CTTATAATTGCACCAATATGGAATTGAAAC	TTGCGGAACTGCGCCGCCGTGGCGTCTGTGTCCTCTA
CTTATAATTGCACCAATATGGAATTGAAAC	TGGAGTAACGAGAAATGCCTCAATCGTCATGATTCCC
CTTATAATTGCACCAATATGGAATTGAAAC	GCATGCGTACCAAGTCCAACTCTGCAAGCAAACGAA
CTTATAATTGCACCAATATGGAATTGAAAC	GCATCAACGGGGAGCAGACAGTGAAGAGGTTAAACG
CTTATAATTGCACCAATATGGAATTGAAAC	CTCGTACTTCTCGACTATCGCAAGCTGCTCTCTGCAT
CTTATAATTGCACCAATATGGAATTGAAAC	CGACAAAGCGTGGAATCAGACCATTGAGGATCATGT
CTTATAATTGCACCAATATGGAATTGAAAC	CAATCAAACATGCAAGTAATTAATAACATCCTGTACAG
CTTATAATTGCACCAATATGGAATTGAAAC	AATTAAAGTTCACAAAAGAGCTGCTGCGCTACTTCAA
CTTATAATTGCACCAATATGGAATTGAAAC	CAGTGCAGGAGGTCATTAATCCTTACATTGTGGTTA
CTTATAATTGCACCAATATGGAATTGAAAC	GTATTTAATGCCACTGAGGAACTGCATGGTATTCCGT
CTTATAATTGCACCAATATGGAATTGAAAC	TAATCATGTTATAGCAAATGTTGACGGTTTGCAAGATG
CTTATAATTGCACCAATATGGAATTGAAAC	TCTGTATCAATCCCCATTGCATGCTTTCGTGCCAGCC
CTTATAATTGCACCAATATGGAATTGAAAC	AGGCTTATTTGCTGCGGGCGGAACGAAACGCTCTTGA
CTTATAATTGCACCAATATGGAATTGAAAC	GCGTTTTTGATGTTCGAGGCAATATGGTGCATATCGAA
CTTATAATTGCACCAATATGGAATTGAAAC	TGTAAGCGCATTGTCGACGCGGTTCATGAGCATCCCGG
CTTATAATTGCACCAATATGGAATTGAAAC	TCCATCCGGAGTTTTCCATTTCTTTGCCTTCGGATT
CTTATAATTGCACCAATATGGAATTGAAAC	TAAGAGGATCAGCGCCCATGCGCTGAGCCATATTCA
CTTATAATTGCACCAATATGGAATTGAAAC	TCGGGTGTCACCCTCACAGCTACTTGAGCCAGCTT
CTTATAATTGCACCAATATGGAATTGAAAC	GCAGCGTAAGAGGTCGTCGCCGACCACTCCGCGTAG
CTTATAATTGCACCAATATGGAATTGAAAC	GTGTCAGTCGTGCCCATTACATCAAGTTTCGTGGGC
CTTATAATTGCACCAATATGGAATTGAAAC	GTTGTCGTCGGTAGAGTGATCTCTGTACCGGACGCATC
CTTATAATTGCACCAATATGGAATTGAAAC	ATCTCAAAAACTGATATAGTCGCTGCAGCATCAGCAC
CTTATAATTGCACCAATATGGAATTGAAAC	CAAAAGGATTCTATCTCGGATGCGGAGGGAGTTCC
CTTATAATTGCACCAATATGGAATTGAAAC	GCGTTCATGTTTTTAAGAACAGCACCTTCATAACCT
CTTATAATTGCACCAATATGGAATTGAAAC	TACTCTTGCGTTATCACCGTAAACGCCACCGTTCGGTATTG
CTTATAATTGCACCAATATGGAATTGAAAC	TTTTTGAACAGTCTTTTTACTTCGCTTCCGAAGCGAT
CTTATAATTGCACCAATATGGAATTGAAAC	ACGTCTGAGGATTTTCGTAACCCATAATCGTGCTTTG
CTTATAATTGCACCAATATGGAATTGAAAC	TCGCAACAAGCTGCTTGCGGAAAGCGGTGCTGAACTCCG
CTTATAATTGCACCAATATGGAATTGAAAC	GTCGATTGAGCCGTTATGCTCGATTCCGTCCAGAAGG
CTTATAATTGCACCAATATGGAATTGAAAC	AGCTCTTGAATCTGGTCTTTAAGCAGCTTGTGTACAGAG
CTTATAATTGCACCAATATGGAATTGAAAC	GCCGAAAGGCCCGACTCAGCAGAAATGCTACGAAATGG
CTTATAATTGCACCAATATGGAATTGAAAC	TGCAAGCGCCTCCTGCTCGTTGCCGCTGCCGCTGAA
CTTATAATTGCACCAATATGGAATTGAAAC	CCGAAAGTGGCGGAGAAGGACATGAAGGCCATGAA
CTTATAATTGCACCAATATGGAATTGAAAC	TCCGACAGCGGGCCTCCACCCTGCGACAAACCAGTT
CTTATAATTGCACCAATATGGAATTGAAAC	TTCGCTATCGATCGTGGAATATCCCTCACGATCGGG
CTTATAATTGCACCAATATGGAATTGAAAC	TCCGAAGCATCACGCTGTCCGGATCGGCGAACGTTG
CTTATAATTGCACCAATATGGAATTGAAAC	TTACCTATTTCGGTAGGTATCTCGGTTTCCGGATCGTTCTT
CTTATAATTGCACCAATATGGAATTGAAAC	TAAGTGTTGGCGCGGAATTGTTTTATTTAAAAAGATC
CTTATAATTGCACCAATATGGAATTGAAAC	AGAGAATATATATTGAATTTGTGAGTCAAGTCAAAC
CTTATAATTGCACCAATATGGAATTGAAAC	CCGGATTAATGTTTATAACCGATGAACCACCGCCG
CTTATAATTGCACCAATATGGAATTGAAAC	TATACCGGAGACGTAGGGAGATGTATGTACGGTGCAA
CTTATAATTGCACCAATATGGAATTGAAAC	AAAACACCCGCCTACGCAGGAATCCACGACACCCTG
CTTATAATTGCACCAATATGGAATTGAAAC	TCGCAGCTGTCATATCGAGATAGGCGTGGCCTGTCTC
CTTATAATTGCACCAATATGGAATTGAAAC	GTCTGGCCCGCGCCGTTCACCTCTGCCGCTGAGCCAC
CTTATAATTGTACCAATATGGAATTGAAAC	AAATAAACAAGCGCTATCGCCAGTTTTTTTTAAACCA
CTTATAATTGCACCAATATGGAATTGAAAC	TAGTAAAAATTTGATGGGTTCGGGTACGCCAGATGCA
CTTATAATTGCACCAATATGGAATTGAAAC	TCGAAGGCCGCAGGCAGCTCTTCAAAGCCCTGCCCCG
CTTATAATTGCACCAATATGGAATTGAAAC	TCAAGAATATGTGAACGATACAATTTCGTTCCTTTTC
CTTATAATTGCACCAATATGGAATTGAAAC	CTTGTACTGCGTAACATAGCCGTAGTAGGCTTTGGAGTT
CTTATAATTGCACCAATATGGAATTGAAAC	GATAGAGGTGTTGTCGCTTCCGCTTCCGCCTGCTTT
CTTATAATTGCACCAATATGGAATTGAAAC	AACACTGGCTGTAATCGGTCAGATACCCCGCTGTCCCG
CTTATAATTGCACCAATATGGAATTGAAAC	TCAGCAAATACGCGGCAAAACGCCGAGACATCACCG
CTTATAATTGCACCAATATGGAATTGAAAC	GCATGCGCAGCTGGGGAGCCGTAGCCATCAGCACCGA
CTTATAATTGCACCAATATGGAATTGAAAC	ATGATCAAGACCGGAGAGCACAAGGTTACCAAGATG
CTTATAATTGCACCAATATGGAATTGAAAC	TAAAAGTAGAAGTAGAAGTAGAAGTAGAAGTAAATG
CTTATAATTGCACCAATATGGAATTGAAAC	GATATTTAGAGTTGCAGATACTGTCGCCCCATCTCC
CTTATAATTGCACCAATATGGAATTGAAAC	GAAAAGAACACCGTTACTGGCAGCGCATGTGCAATT
CTTATAATTGCACCAATATGGAATTGAAAC	TGAGCTACAAGCATCCTGATCAGCCTACAAGCACTC
CTTATAATTGCACCAATATGGAATTGAAAC	GACACGGTTATACATGAAAGGATCGGCACGTAGCTGG
CTTATAATTGCACCAATATGGAATTGAAAC	GCAAATCATTGCAAGCTGTGAGGACAGCATCGATCT
CTTATAATTGCACCAATATGGAATTGAAAC	CTTATCGTCACCATGCAATTCTTTATGATTTCTTTTCT
CTTATAATTGCACCAATATGGAATTGAAAC	GCGATAGACGCCTGTACCTGTATTTCGAGTATCTTC
CTTATAATTGCACCAATATGGAATTGAAAC	GGTGAATTGCCGCCAGTAGCATTTTCAGAAATCGTACAA
CTTATAATTGCACCAATATGGAATTGAAAC	GCGATAGACGCCTGTACCTGTATTTCGAGTATCTTT
CTTATAATTGCACCAATATGGAATTGAAAC	AAAGCCCTGCAGGGATACCTTCCCGAAACGTCCTGA
CTTATAATTGCACCAATATGGAATTGAAAC	CCGTAATGGCCGCGTTGTCTGCCGGCGCATTGCTTA
CTTATAATTGCACCAATATGGAATTGAAAC	CGATGATTGATAAGGTTTATGTAGATGCTCAACAAG
CTTATAATTGCACCAATATGGAATTGAAAC	TTGTGCCGCATATCGTTTTACCGACTCCAGCAAAACGT
CTTATAATTGCACCAATATGGAATTGAAAC	AAATATTCCGTACCCCTCAAGGCCGAGCTGATCCAT
CTTATAATTGCACCAATATGGAATTGAAAC	ATGCAAGACATCTCTTGATCTCGTTCGTTTATTCGCTC
CTTATAATTGCACCAATATGGAATTGAAAC	ACTGATTTTTCGATCTCGGCCATAGGCGTCTTGAA
CTTATAATTGCACCAATATGGAATTGAAAC	ACCGTACCATAGCCACAACAGGCTTCGACACCAGCGC
CTTATAATTGCACCAATATGGAATTGAAAC	TGAACCAGCTCATCCGCTGGATCCTCGAACTCAACCG
CTTATAATTGCACCAATATGGAATTGAAAC	CCGGAAACTCTTTATCATATCTCCTCCATGTCAAGCA
CTTATAATTGCACCAATATGGAATTGAAAC	GCCTTCCTTGGCCACAAAAAGGTCAGGAAGTATCCAT
CTTATAATTGCACCAATATGGAATTGAAAC	TAAAAGTAGAAGTAGAAGTAGAAGTAGAAGTAAATG
CTTATAATTGCACCAATATGGAATTGAAAC	AGAATTTTCATTCGGTGTTTGAAATAAATCTCAACAA
CTTATAATTGCACCAATATGGAATTGAAAC	GAGGACGGTTATTGTCCCTGTGACATCGATAGTGCTG
CTTATAATTGCACCAATATGGAATTGAAAC	TCAGGCTCATGATGTAATCCATCGCCCATCATTTCG
CTTATAATTGCACCAATATGGAATTGAAAC	TCGATCCGGCATTCCCGGATGATGAAGCGCCGTTTTA
CTTATAATTGCACCAATATGGAATTGAAAC	CATGGACAGGTTGCAAGGTTGGACTGGTTTCCGGTTTG
CTTATAATTGCACCAATATGGAATTGAAAC	CCTTTTTGGCGGCTCCGAACGATCGAATCGGTTGCCCG
CTTATAATAGCACCAATATGGAATTGAAAC

>NC_010803|2|1|499776-508012|CRT
CTTATAATTGCACCAATATGGAATTGAAAC	CAGTGATAATATCTAATTCCTTCGCCGTATTCTTTTC
CTTATAATTGCACCAATATGGAATTGAAAC	ACGTTCTTGATATGCGAATACGTTACCATCGTTGGC
CTTATAATTGCACCAATATGGAATTGAAAC	CAGGGCAACCTTTCCGCAATCGGTACATTTACCGCTC
CTTATAATTGCACCAATATGGAATTGAAAC	TAAAAACGTAACCTCTCCGATGCAGGTTATGCGAGGA
CTTATAATTGCACCAATATGGAATTGAAAC	CTATCTTCACTGTGGTGAATACGGTGATAAAACTG
CTTATAATTGCACCAATATGGAATTGAAAC	TACGGATGGTACAACATCTTTCGGTCTGGAATCTAA
CTTATAATTGCACCAATATGGAATTGAAAC	TTAAAGAACGAACAGCTCGCGTTATGCCTCTCTACTC
CTTATAATTGCACCAATATGGAATTGAAAC	ACGCTAGAATTAGTAATCGGCTGAGTACCTCCTGTATTA
CTTATAATTGCACCAATATGGAATTGAAAC	AGATTTGTAGTTCCCTCGGTGAGACCAAGAGCTTTA
CTTATAATTGCACCAATATGGAATTGAAAC	TTACCGCCCATAGCCGACAGTACTGGATTTAGACCT
CTTATAATTGCACCAATATGGAATTGAAAC	TATAAAGAACGCCTTAGTAATGTCTTATTAGGTGCT
CTTATAATTGCACCAATATGGAATTGAAAC	TAGCAATTGCTAAAGTATTTGAAGCCTCTTGTAAGG
CTTATAATTGCACCAATATGGAATTGAAAC	TGTAATCGTTCCCGGCAAGCATTGCCTTTACACCG
CTTATAATTGCACCAATATGGAATTGAAAC	GTCGTTTCGGGTGAGTTCAGTGATCTCCTCGACCC
CTTATAATTGCACCAATATGGAATTGAAAC	GAGACCGCAAACATCAGCAGCATGTAGGCTGGATTG
CTTATAATTGCACCAATATGGAATTGAAAC	ATATAGGCTTGATCGGTGTTGCAAGCCGCCCAAATCC
CTTATAATTGCACCAATATGGAATTGAAAC	CAGGGTATCTGAATCGGCATATCGGAATAAGCTTCT
CTTATAATTGCACCAATATGGAATTGAAAC	TTATTGATTCAACAACCTCATCAACCTTTTCCGGAG
CTTATAATTGCACCAATATGGAATTGAAAC	GCGACATCGCAACGCAGGCCCTTGTCGACGGGCTC
CTTATAATTGCACCAATATGGAATTGAAAC	TCAAGAACAACAGCGTTACCGGAGACAGATCGTGTGT
CTTATAATTGCACCAATATGGAATTGAAAC	CAGTGCGGGCATGGCACAAAGTTCCGGCGCTGGTC
CTTATAATTGCACCAATATGGAATTGAAAC	TTGAGTAGGCCTCCGCGATATCGAGCGTCGGGAGTA
CTTATAATTGCACCAATATGGAATTGAAAC	TTGCACTCCGTGACGGGTAAGCCCGTCTGATTCCG
CTTATAATTGCACCAATATGGAATTGAAAC	TTGAAAGCTGATCCGCATAGTCTGCGAGCTGTGATG
CTTATAATTGCACCAATATGGAATTGAAAC	CTTGCTATTTGTTGCAGGGTTGGCAAGGTTCGTCACAG
CTTATAATTGCACCAATATGGAATTGAAAC	TCGTTCATCTCATGCACCAGCCCCGCAAGCGAAACCC
CTTATAATTGCACCAATATGGAATTGAAAC	GCATTACAGCAACACGTCCCTGTCTGTCTATTGCGGA
CTTATAATTGCACCAATATGGAATTGAAAC	TTAAGTTGCGTCCTTCCGCCTGAGCCGTCTTGATGA
CTTATAATTGCACCAATATGGAATTGAAAC	CATTGAGAGCATTGACGCACACGTACGCGGCATTCAG
CTTATAATTGCACCAATATGGAATTGAAAC	CAGCAATCGTCGATAAGCGAGTGATGATCTTACTGTTC
CTTATAATTGCACCAATATGGAATTGAAAC	ACAGATTCGCCGAGTCCAGCGCAGCAAGCGCCGCCT
CTTATAATTGCACCAATATGGAATTGAAAC	CCCGGAAGGCCAAGTCCATCCAGATACGCCTGTTCAA
CTTATAATTGCACCAATATGGAATTGAAAC	TGAGCTTGCTCAAACGCTCGGCATCGCCGTCATGGTG
CTTATAATTGCACCAATATGGAATTGAAAC	GGATGAGCCATCGATGTTTCCCGATACGCATTCCGA
CTTATAATTGCACCAATATGGAATTGAAAC	GCGCATCAACACCGCCCTTAAAGAGAGCCTCACCG
CTTATAATTGCACCAATATGGAATTGAAAC	GCTGCAGGAAGTCAAAACAAAATTCCCGTTCTGGGAA
CTTATAATTGCACCAATATGGAATTGAAAC	GTTTTTCGAGTGGAAGATAAGCCAGGGGAGGACTGAA
CTTATAATTGCACCAATATGGAATTGAAAC	ATTCGCTCCGCATGTCTGATGACGCTCCGGTAAATCT
CTTATAATTGCACCAATATGGAATTGAAAC	AAAAGCGTATTCCCGACAATGGCGATTTTCCCTTCCGA
CTTATAATTGCACCAATATGGAATTGAAAC	GGGTAGCTATCTATTATTTCGTCAATGAGCCATAGCGT
CTTATAATTGCACCAATATGGAATTGAAAC	TTCTTCCACGGAATAGCGTTGTAGCCACCCTTTCGCAA
CTTATAATTGCACCAATATGGAATTGAAAC	TTGCGGAACTGCGCCGCCGTGGCGTCTGTGTCCTCTA
CTTATAATTGCACCAATATGGAATTGAAAC	TGGAGTAACGAGAAATGCCTCAATCGTCATGATTCCC
CTTATAATTGCACCAATATGGAATTGAAAC	GCATGCGTACCAAGTCCAACTCTGCAAGCAAACGAA
CTTATAATTGCACCAATATGGAATTGAAAC	GCATCAACGGGGAGCAGACAGTGAAGAGGTTAAACG
CTTATAATTGCACCAATATGGAATTGAAAC	CTCGTACTTCTCGACTATCGCAAGCTGCTCTCTGCAT
CTTATAATTGCACCAATATGGAATTGAAAC	CGACAAAGCGTGGAATCAGACCATTGAGGATCATGT
CTTATAATTGCACCAATATGGAATTGAAAC	CAATCAAACATGCAAGTAATTAATAACATCCTGTACAG
CTTATAATTGCACCAATATGGAATTGAAAC	AATTAAAGTTCACAAAAGAGCTGCTGCGCTACTTCAA
CTTATAATTGCACCAATATGGAATTGAAAC	CAGTGCAGGAGGTCATTAATCCTTACATTGTGGTTA
CTTATAATTGCACCAATATGGAATTGAAAC	GTATTTAATGCCACTGAGGAACTGCATGGTATTCCGT
CTTATAATTGCACCAATATGGAATTGAAAC	TAATCATGTTATAGCAAATGTTGACGGTTTGCAAGATG
CTTATAATTGCACCAATATGGAATTGAAAC	TCTGTATCAATCCCCATTGCATGCTTTCGTGCCAGCC
CTTATAATTGCACCAATATGGAATTGAAAC	AGGCTTATTTGCTGCGGGCGGAACGAAACGCTCTTGA
CTTATAATTGCACCAATATGGAATTGAAAC	GCGTTTTTGATGTTCGAGGCAATATGGTGCATATCGAA
CTTATAATTGCACCAATATGGAATTGAAAC	TGTAAGCGCATTGTCGACGCGGTTCATGAGCATCCCGG
CTTATAATTGCACCAATATGGAATTGAAAC	TCCATCCGGAGTTTTCCATTTCTTTGCCTTCGGATT
CTTATAATTGCACCAATATGGAATTGAAAC	TAAGAGGATCAGCGCCCATGCGCTGAGCCATATTCA
CTTATAATTGCACCAATATGGAATTGAAAC	TCGGGTGTCACCCTCACAGCTACTTGAGCCAGCTT
CTTATAATTGCACCAATATGGAATTGAAAC	GCAGCGTAAGAGGTCGTCGCCGACCACTCCGCGTAG
CTTATAATTGCACCAATATGGAATTGAAAC	GTGTCAGTCGTGCCCATTACATCAAGTTTCGTGGGC
CTTATAATTGCACCAATATGGAATTGAAAC	GTTGTCGTCGGTAGAGTGATCTCTGTACCGGACGCATC
CTTATAATTGCACCAATATGGAATTGAAAC	ATCTCAAAAACTGATATAGTCGCTGCAGCATCAGCAC
CTTATAATTGCACCAATATGGAATTGAAAC	CAAAAGGATTCTATCTCGGATGCGGAGGGAGTTCC
CTTATAATTGCACCAATATGGAATTGAAAC	GCGTTCATGTTTTTAAGAACAGCACCTTCATAACCT
CTTATAATTGCACCAATATGGAATTGAAAC	TACTCTTGCGTTATCACCGTAAACGCCACCGTTCGGTATTG
CTTATAATTGCACCAATATGGAATTGAAAC	TTTTTGAACAGTCTTTTTACTTCGCTTCCGAAGCGAT
CTTATAATTGCACCAATATGGAATTGAAAC	ACGTCTGAGGATTTTCGTAACCCATAATCGTGCTTTG
CTTATAATTGCACCAATATGGAATTGAAAC	TCGCAACAAGCTGCTTGCGGAAAGCGGTGCTGAACTCCG
CTTATAATTGCACCAATATGGAATTGAAAC	GTCGATTGAGCCGTTATGCTCGATTCCGTCCAGAAGG
CTTATAATTGCACCAATATGGAATTGAAAC	AGCTCTTGAATCTGGTCTTTAAGCAGCTTGTGTACAGAG
CTTATAATTGCACCAATATGGAATTGAAAC	GCCGAAAGGCCCGACTCAGCAGAAATGCTACGAAATGG
CTTATAATTGCACCAATATGGAATTGAAAC	TGCAAGCGCCTCCTGCTCGTTGCCGCTGCCGCTGAA
CTTATAATTGCACCAATATGGAATTGAAAC	CCGAAAGTGGCGGAGAAGGACATGAAGGCCATGAA
CTTATAATTGCACCAATATGGAATTGAAAC	TCCGACAGCGGGCCTCCACCCTGCGACAAACCAGTT
CTTATAATTGCACCAATATGGAATTGAAAC	TTCGCTATCGATCGTGGAATATCCCTCACGATCGGG
CTTATAATTGCACCAATATGGAATTGAAAC	TCCGAAGCATCACGCTGTCCGGATCGGCGAACGTTG
CTTATAATTGCACCAATATGGAATTGAAAC	TTACCTATTTCGGTAGGTATCTCGGTTTCCGGATCGTTCTT
CTTATAATTGCACCAATATGGAATTGAAAC	TAAGTGTTGGCGCGGAATTGTTTTATTTAAAAAGATC
CTTATAATTGCACCAATATGGAATTGAAAC	AGAGAATATATATTGAATTTGTGAGTCAAGTCAAAC
CTTATAATTGCACCAATATGGAATTGAAAC	CCGGATTAATGTTTATAACCGATGAACCACCGCCG
CTTATAATTGCACCAATATGGAATTGAAAC	TATACCGGAGACGTAGGGAGATGTATGTACGGTGCAA
CTTATAATTGCACCAATATGGAATTGAAAC	AAAACACCCGCCTACGCAGGAATCCACGACACCCTG
CTTATAATTGCACCAATATGGAATTGAAAC	TCGCAGCTGTCATATCGAGATAGGCGTGGCCTGTCTC
CTTATAATTGCACCAATATGGAATTGAAAC	GTCTGGCCCGCGCCGTTCACCTCTGCCGCTGAGCCAC
CTTATAATTGTACCAATATGGAATTGAAAC	AAATAAACAAGCGCTATCGCCAGTTTTTTTTAAACCA
CTTATAATTGCACCAATATGGAATTGAAAC	TAGTAAAAATTTGATGGGTTCGGGTACGCCAGATGCA
CTTATAATTGCACCAATATGGAATTGAAAC	TCGAAGGCCGCAGGCAGCTCTTCAAAGCCCTGCCCCG
CTTATAATTGCACCAATATGGAATTGAAAC	TCAAGAATATGTGAACGATACAATTTCGTTCCTTTTC
CTTATAATTGCACCAATATGGAATTGAAAC	CTTGTACTGCGTAACATAGCCGTAGTAGGCTTTGGAGTT
CTTATAATTGCACCAATATGGAATTGAAAC	GATAGAGGTGTTGTCGCTTCCGCTTCCGCCTGCTTT
CTTATAATTGCACCAATATGGAATTGAAAC	AACACTGGCTGTAATCGGTCAGATACCCCGCTGTCCCG
CTTATAATTGCACCAATATGGAATTGAAAC	TCAGCAAATACGCGGCAAAACGCCGAGACATCACCG
CTTATAATTGCACCAATATGGAATTGAAAC	GCATGCGCAGCTGGGGAGCCGTAGCCATCAGCACCGA
CTTATAATTGCACCAATATGGAATTGAAAC	ATGATCAAGACCGGAGAGCACAAGGTTACCAAGATG
CTTATAATTGCACCAATATGGAATTGAAAC	TAAAAGTAGAAGTAGAAGTAGAAGTAGAAGTAAATG
CTTATAATTGCACCAATATGGAATTGAAAC	GATATTTAGAGTTGCAGATACTGTCGCCCCATCTCC
CTTATAATTGCACCAATATGGAATTGAAAC	GAAAAGAACACCGTTACTGGCAGCGCATGTGCAATT
CTTATAATTGCACCAATATGGAATTGAAAC	TGAGCTACAAGCATCCTGATCAGCCTACAAGCACTC
CTTATAATTGCACCAATATGGAATTGAAAC	GACACGGTTATACATGAAAGGATCGGCACGTAGCTGG
CTTATAATTGCACCAATATGGAATTGAAAC	GCAAATCATTGCAAGCTGTGAGGACAGCATCGATCT
CTTATAATTGCACCAATATGGAATTGAAAC	CTTATCGTCACCATGCAATTCTTTATGATTTCTTTTCT
CTTATAATTGCACCAATATGGAATTGAAAC	GCGATAGACGCCTGTACCTGTATTTCGAGTATCTTC
CTTATAATTGCACCAATATGGAATTGAAAC	GGTGAATTGCCGCCAGTAGCATTTTCAGAAATCGTACAA
CTTATAATTGCACCAATATGGAATTGAAAC	GCGATAGACGCCTGTACCTGTATTTCGAGTATCTTT
CTTATAATTGCACCAATATGGAATTGAAAC	AAAGCCCTGCAGGGATACCTTCCCGAAACGTCCTGA
CTTATAATTGCACCAATATGGAATTGAAAC	CCGTAATGGCCGCGTTGTCTGCCGGCGCATTGCTTA
CTTATAATTGCACCAATATGGAATTGAAAC	CGATGATTGATAAGGTTTATGTAGATGCTCAACAAG
CTTATAATTGCACCAATATGGAATTGAAAC	TTGTGCCGCATATCGTTTTACCGACTCCAGCAAAACGT
CTTATAATTGCACCAATATGGAATTGAAAC	AAATATTCCGTACCCCTCAAGGCCGAGCTGATCCAT
CTTATAATTGCACCAATATGGAATTGAAAC	ATGCAAGACATCTCTTGATCTCGTTCGTTTATTCGCTC
CTTATAATTGCACCAATATGGAATTGAAAC	ACTGATTTTTCGATCTCGGCCATAGGCGTCTTGAA
CTTATAATTGCACCAATATGGAATTGAAAC	ACCGTACCATAGCCACAACAGGCTTCGACACCAGCGC
CTTATAATTGCACCAATATGGAATTGAAAC	TGAACCAGCTCATCCGCTGGATCCTCGAACTCAACCG
CTTATAATTGCACCAATATGGAATTGAAAC	CCGGAAACTCTTTATCATATCTCCTCCATGTCAAGCA
CTTATAATTGCACCAATATGGAATTGAAAC	GCCTTCCTTGGCCACAAAAAGGTCAGGAAGTATCCAT
CTTATAATTGCACCAATATGGAATTGAAAC	TAAAAGTAGAAGTAGAAGTAGAAGTAGAAGTAAATG
CTTATAATTGCACCAATATGGAATTGAAAC	AGAATTTTCATTCGGTGTTTGAAATAAATCTCAACAA
CTTATAATTGCACCAATATGGAATTGAAAC	GAGGACGGTTATTGTCCCTGTGACATCGATAGTGCTG
CTTATAATTGCACCAATATGGAATTGAAAC	TCAGGCTCATGATGTAATCCATCGCCCATCATTTCG
CTTATAATTGCACCAATATGGAATTGAAAC	TCGATCCGGCATTCCCGGATGATGAAGCGCCGTTTTA
CTTATAATTGCACCAATATGGAATTGAAAC	CATGGACAGGTTGCAAGGTTGGACTGGTTTCCGGTTTG
CTTATAATTGCACCAATATGGAATTGAAAC	CCTTTTTGGCGGCTCCGAACGATCGAATCGGTTGCCCG
CTTATAATAGCACCAATATGGAATTGAAAC

Protein	Signature genes	Signature genes Name	Protein_function
NC_010803.1\|WP_150081512.1\|514487_515207_-\|DUF1003-domain-containing-protein	unknown	unknown	gnl\|CDD\|377629
NC_010803.1\|WP_012465415.1\|492170_493559_+\|type-I-B-CRISPR-associated-protein-Cas8b1/Cst1	cas8b2	cd09665_cas8b2_CAS-I-B	gnl\|CDD\|187796
NC_010803.1\|WP_012465418.1\|495231_497484_+\|CRISPR-associated-helicase/endonuclease-Cas3	cas3	COG1203_cas3_CAS-I	gnl\|CDD\|224124
NC_010803.1\|WP_012465430.1\|518289_518454_+\|hypothetical-protein	unknown	unknown	unknown
NC_010803.1\|WP_012465420.1\|498774_499035_+\|CRISPR-associated-endonuclease-Cas2	cas2	cd09725_cas2_CAS-I:CAS-II:CAS-III:CAS-V	gnl\|CDD\|187856
NC_010803.1\|WP_012465432.1\|521461_522343_+\|ABC-transporter-permease	unknown	unknown	gnl\|CDD\|224005
NC_010803.1\|WP_012465421.1\|499041_499542_+\|CRISPR-associated-protein-Cas4	cas4	pfam01930_cas4_CAS-I	gnl\|CDD\|366863
NC_010803.1\|WP_012465429.1\|515187_518043_-\|excinuclease-ABC-subunit-UvrA	unknown	unknown	gnl\|CDD\|234734
NC_010803.1\|WP_012465413.1\|490314_491397_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|370761
NC_010803.1\|WP_012465426.1\|512844_513864_+\|6-phosphofructokinase	unknown	unknown	gnl\|CDD\|235111
NC_010803.1\|WP_012465425.1\|510982_512656_+\|class-I-SAM-dependent-methyltransferase	unknown	unknown	gnl\|CDD\|367049
NC_010803.1\|WP_012465414.1\|491386_492178_+\|nucleotidyl-transferase-AbiEii/AbiGii-toxin-family-protein	unknown	unknown	gnl\|CDD\|227186
NC_010803.1\|WP_012465431.1\|518554_521305_-\|pyruvate,-phosphate-dikinase	unknown	unknown	gnl\|CDD\|236446
NC_010803.1\|WP_012465419.1\|497488_498643_+\|type-I-B-CRISPR-associated-endonuclease-Cas1	cas1	cd09722_cas1_CAS-I-B	gnl\|CDD\|274695
NC_010803.1\|WP_012465424.1\|510630_510876_+\|hypothetical-protein	unknown	unknown	unknown
NC_010803.1\|WP_012465422.1\|508432_510424_+\|DUF2934-domain-containing-protein	unknown	unknown	gnl\|CDD\|176529
NC_010803.1\|WP_012465427.1\|513898_514474_+\|HD-domain-containing-protein	unknown	unknown	unknown
NC_010803.1\|WP_012465416.1\|493581_494607_+\|type-I-B-CRISPR-associated-protein-Cas7/Cst2/DevR	cas7	cd09687_cas7_CAS-I-B	gnl\|CDD\|187818
NC_010803.1\|WP_190275093.1\|489490_490213_+\|CRISPR-associated-endoribonuclease-Cas6	cas6	COG1583_cas6_CAS-I:CAS-III:CAS-IV	gnl\|CDD\|187889
NC_010803.1\|WP_012465417.1\|494609_495230_+\|type-I-B-CRISPR-associated-protein-Cas5	cas5	COG1688_cas5_CAS-I	gnl\|CDD\|273860

Protein	Function_ID	Function_description	E-value
NC_010803.1\|WP_150081512.1\|514487_515207_-\|DUF1003-domain-containing-protein	gnl\|CDD\|377629	pfam06210, DUF1003, Protein of unknown function (DUF1003). This family consists of several hypothetical bacterial proteins of unknown function.	3.09469e-54
NC_010803.1\|WP_012465415.1\|492170_493559_+\|type-I-B-CRISPR-associated-protein-Cas8b1/Cst1	gnl\|CDD\|187796	cd09665, Cas8a1_I-A, CRISPR/Cas system-associated protein Cas8a1. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Large proteins, some contain Zn-finger domain; signature gene for I-A subtype; also known as CXXC_CXXC family.	1.1709e-41
NC_010803.1\|WP_012465418.1\|495231_497484_+\|CRISPR-associated-helicase/endonuclease-Cas3	gnl\|CDD\|224124	COG1203, COG1203, CRISPR-associated helicase Cas3 [Defense mechanisms].	2.86504e-89
NC_010803.1\|WP_012465420.1\|498774_499035_+\|CRISPR-associated-endonuclease-Cas2	gnl\|CDD\|187856	cd09725, Cas2_I_II_III, CRISPR/Cas system-associated protein Cas2. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas2 is present in majority of CRISPR/Cas systems along with Cas1; RNAse specific to U-rich regions; Possesses an RRM/ferredoxin fold.	2.16883e-29
NC_010803.1\|WP_012465421.1\|499041_499542_+\|CRISPR-associated-protein-Cas4	gnl\|CDD\|366863	pfam01930, Cas_Cas4, Domain of unknown function DUF83. This domain has no known function. The domain contains three conserved cysteines at its C-terminus.	6.6346e-61
NC_010803.1\|WP_012465429.1\|515187_518043_-\|excinuclease-ABC-subunit-UvrA	gnl\|CDD\|234734	PRK00349, uvrA, excinuclease ABC subunit UvrA.	0
NC_010803.1\|WP_012465413.1\|490314_491397_+\|hypothetical-protein	gnl\|CDD\|370761	pfam09952, AbiEi_2, Transcriptional regulator, AbiEi antitoxin, Type IV TA system. AbiEi_2 is the cognate antitoxin of the type IV toxin-antitoxin 'innate immunity' bacterial abortive infection (Abi) system that protects bacteria from the spread of a phage infection. The Abi system is activated upon infection with phage to abort the cell thus preventing the spread of phage through viral replication. There are some 20 or more Abis, and they are predominantly plasmid-encoded lactococcal systems. TA, toxin-antitoxin, systems on plasmids function by killing cells that lose the plasmid upon division. AbiE phage resistance systems function as novel Type IV TAs and are widespread in bacteria and archaea. The cognate antitoxin is pfam13338.	1.6276e-10
NC_010803.1\|WP_012465426.1\|512844_513864_+\|6-phosphofructokinase	gnl\|CDD\|235111	PRK03202, PRK03202, ATP-dependent 6-phosphofructokinase.	2.99432e-177
NC_010803.1\|WP_012465425.1\|510982_512656_+\|class-I-SAM-dependent-methyltransferase	gnl\|CDD\|367049	pfam02353, CMAS, Mycolic acid cyclopropane synthetase. This family consist of Cyclopropane-fatty-acyl-phospholipid synthase or CFA synthase EC:2.1.1.79 this enzyme catalyze the reaction: S-adenosyl-L-methionine + phospholipid olefinic fatty acid <=> S-adenosyl-L-homocysteine + phospholipid cyclopropane fatty acid.	9.65217e-11
NC_010803.1\|WP_012465414.1\|491386_492178_+\|nucleotidyl-transferase-AbiEii/AbiGii-toxin-family-protein	gnl\|CDD\|227186	COG4849, COG4849, Predicted nucleotidyltransferase [General function prediction only].	2.94789e-05
NC_010803.1\|WP_012465432.1\|521461_522343_+\|ABC-transporter-permease	gnl\|CDD\|224005	COG1079, COG1079, Uncharacterized ABC-type transport system, permease component [General function prediction only].	3.92577e-76
NC_010803.1\|WP_012465419.1\|497488_498643_+\|type-I-B-CRISPR-associated-endonuclease-Cas1	gnl\|CDD\|274695	TIGR03641, cas1_HMARI, CRISPR-associated endonuclease Cas1, subtype I-B/HMARI/TNEAP. The CRISPR-associated protein Cas1 is virtually universal to CRISPR systems. CRISPR, an acronym for Clustered Regularly Interspaced Short Palindromic Repeats, is prokaryotic immunity system for foreign DNA, mostly from phage. CRISPR systems belong to different subtypes, distinguished by both nature of the repeats, the makeup of the cohort of associated Cas proteins, and by molecular phylogeny within the more universal Cas proteins such as this one. This model is of type EXCEPTION and provides more specific information than the EQUIVALOG model TIGR00287. It describes Cas1 subgroup that includes Cas1 proteins of the related HMARI and TNEAP subtypes of CRISPR/Cas system.	1.80182e-165
NC_010803.1\|WP_012465431.1\|518554_521305_-\|pyruvate,-phosphate-dikinase	gnl\|CDD\|236446	PRK09279, PRK09279, pyruvate phosphate dikinase; Provisional.	0
NC_010803.1\|WP_012465422.1\|508432_510424_+\|DUF2934-domain-containing-protein	gnl\|CDD\|176529	cd08587, PI-PLCXDc_like, Catalytic domain of phosphatidylinositol-specific phospholipase C X domain containing and similar proteins. This family corresponds to the catalytic domain present in phosphatidylinositol-specific phospholipase C X domain containing proteins (PI-PLCXD) which are bacterial phosphatidylinositol-specific phospholipase C (PI-PLC, EC 4.6.1.13) sequence homologs mainly found in eukaryota. The typical eukaryotic phosphoinositide-specific phospholipase C (PI-PLC, EC 3.1.4.11) have a multidomain organization that consists of a PLC catalytic core domain, and various regulatory domains. The catalytic core domain is assembled from two highly conserved X- and Y-regions split by a divergent linker sequence. In contrast, eukaryotic PI-PLCXDs and their bacterial homologs contain a single TIM-barrel type catalytic domain, X domain, which is more closely related to that of bacterial PI-PLCs. Although the biological function of eukaryotic PI-PLCXDs still remains unclear, it may be distinct from that of typical eukaryotic PI-PLCs.	2.61443e-28
NC_010803.1\|WP_012465416.1\|493581_494607_+\|type-I-B-CRISPR-associated-protein-Cas7/Cst2/DevR	gnl\|CDD\|187818	cd09687, Cas7_I-C, CRISPR/Cas system-associated RAMP superfamily protein Cas7. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas7 is a RAMP superfamily protein; Subunit of the Cascade complex; also known as Cst2/DevR family.	1.62503e-54
NC_010803.1\|WP_190275093.1\|489490_490213_+\|CRISPR-associated-endoribonuclease-Cas6	gnl\|CDD\|187889	cd09759, Cas6_I-A, CRISPR/Cas system-associated RAMP superfamily protein Cas6. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas6 is an endoribonuclease that generates crRNAs, predicted subunit of Cascade complex; RAMP superfamily protein; Possesses double RRM/ferredoxin fold.	8.09578e-40
NC_010803.1\|WP_012465417.1\|494609_495230_+\|type-I-B-CRISPR-associated-protein-Cas5	gnl\|CDD\|273860	TIGR01895, conserved_hypothetical_protein, CRISPR-associated protein Cas5, subtype I-B/TNEAP. CRISPR is a term for Clustered Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR associated) proteins. This family is represented by TM1800 from Thermotoga maritima. It is related to TIGR01868 (CRISPR-associated protein, CT1976 family).	2.95856e-45

>NC_010803.1|WP_012465421.1|499041_499542_+|CRISPR-associated-protein-Cas4
MLNPRVNGTKISYYFICHRKLWLFDRQLQFESDFSPVEEGKFISETTYPDERHEIKLSDGAVLDFYDKKHKVVHEVKKSDKMEEAHLWQLKYYLYYLKSYGVNGVTGKLDYPKLKKTLDVELRDEDELRIQEIFDDMTRVVTQEKAPERINKKFCKTCAYYEFCWA
>NC_010803.1|WP_012465420.1|498774_499035_+|CRISPR-associated-endonuclease-Cas2
MYYIAVYDVAEKRVGKMLKIFRKYMHHIQNSVFEGEMTPASYQKLKYEAGRLCNDETDSVIFFELNGKYMNKEILGTEKRPASNFI
>NC_010803.1|WP_012465419.1|497488_498643_+|type-I-B-CRISPR-associated-endonuclease-Cas1
MPISIPTKQPFYIFSNGVLLRKENTISFVPYVTQDEITVETNPSLYLEPDEEEAYSLNPVKDEHLNTAARRVIPINNIDSFFVFGEVSFNTKFLNFLTRNRIPLHLFNYYGFYSGSYYPREHLLSGYLVVNQVKHYSSTKKRLEIAREFIGAAAANIIRNLKYYTADSRQGVQDDESLAMLFHTIAQIESLANGIAAAQDIPSLMGVEGNIRKVYYQVWQQLLRSADPAFSFSERVKRPPDNAVNALVSFGNSLMYSACLTEIYRTQLNPTVSFLHEPSERRFSLALDMAEVFKPMFIDRLIFKLVNTRAIQARHFTTALNFCHLNDAGRKIVVKEFEERMRTTIKHRGLDRNVSYRRLIRLECYKLIKHLIGEEPYHAFRTWW
>NC_010803.1|WP_012465418.1|495231_497484_+|CRISPR-associated-helicase/endonuclease-Cas3
MIEVYAKSSPKETLLEHTEKCLSVFRNIREMYSEVPEICSCEDFFEHLFYAIFLHDFGKAATGFQQMLNEEIKWNYRHEILSSSFVTFLDFDSPFKEGIALGIITHHNDLSLLQEKFPFSKFNETAYERYSKNLSELEPNFAYITKMMEQLPELSEKYLGYRVKRHKIPKSFEELEAYNAYQSAVKPYLKWDDDEDEQAILHGEYGFFLKGFMTACDHLASSGKDEIFSAIHDMKAVFKFSSYRSSQEAAAVTKGSTFLTAPTGSGKTEAALLWASSNQNERLGKRVFYVLPYTASINAMYKRLAGLKGFGDEKVGIRHGKASYFLYKYFSEREYSPEEAKAFAKDAGNLSKKIYKPYKIITPFQIIKEFFGLKGFEQRIAEMTGGLFILDEIHAYDVHNTALILEICKILKKEFCAKFFIMSATLPKFLKMYFQDVLEIENEITLPPEELHSFTRHKLLLLEGNIRDGLAQIRSEIKTGKKVLVVCNQVKTAQEIFRGLKDCSENSALLHSRFIVRDRQEIEKYVNDKYDLLVATQIVEVSLDIDYDILFSEPAPIDALIQRFGRVNRKRPPINEIKAVCVFQSPSENDFWIYKPERVEKTLSILQKVHGENLSESIVQQLVDEVYADGYKGKDLEEFESIRSNFMKLWKETLPFIDDRRKEEDFYALFDSIEVVPEKYMSDYELCINKKDYFRTTEFFVTINRRQYANLYKAGQVYQEKIGDDNVLFIKTAYDHEYGLLIDKYDDNMI
>NC_010803.1|WP_012465417.1|494609_495230_+|type-I-B-CRISPR-associated-protein-Cas5
MKLLRIKIRSWTASFRYPIFVAGFQPTLPMPPLSTIYGLISAAKGNIVTPEETSVGYVFSYQAKAVDLETIYEIEGLKAKSNVANREFLFDNELYLYLTNLDLESVFRRPHHPILLGRSTELAMIEEVKILELKEKTGVKVGKTLMPIPAKGFYGALQALPTHFSDEVNRKALGTKPFLMVEEMITTTENPVPFDEEKKWGVFLHQ
>NC_010803.1|WP_012465416.1|493581_494607_+|type-I-B-CRISPR-associated-protein-Cas7/Cst2/DevR
MSKNIIGFMLIDAPYSALNNAGSDAGERTENTISVKSIRKGKDIYPYISAQALRYWWRETLEKKCSWEMSPIERETKIAFTQANPFKYPDDDVFGYMRAQGKSDGGTVTRLSPLKNSPLISIVPNQMTSDFGVMSRQKEGDPVPHEHQFYSTVMHGIFSLDLESVGIFLENYKTGQRHLNDKLVQKHRDSIEKSGAVKTENDYRLPKDERTKRVTEAISVLPFISGGAKSALHLTDVTPKLLVMTIFNSGNHIFMNLAKNDNGQPKVNICALEQVLTDYADYLATDVYIARRVGFMDELEEELVSLNEKAFGTKKVIYNMDGSFNKTVETFTQEIATSIPE
>NC_010803.1|WP_012465415.1|492170_493559_+|type-I-B-CRISPR-associated-protein-Cas8b1/Cst1
MSSLFQYTGNPFVDAGISALTNWCDKKTPQELTEADIKKALPEIANLFSQGAWVKTFYTTFSNGVMVQPSNKGKEREKWLEFIGDLVKELQPLADHGSCVACGCRNAIKIKKEKRGLLRSEVPMASGSLNYYSFASTGADYCGTCAIAIQVSPLVLYRSGGKMILVHSSSEKAMCSWAKMAINEVRSQISLRNYTGCFTENFTNPQNALFRIAKILIQDKDDWKSDPITIRIYYFTNYGQGAELKYYDLPNRVFHFLNEVHHSEELKDWDKIIGSTYFFKKNNSKIYLNTDDKSEEEYKNNNNVIYEGLLKDEWIVKYFYNFLQRKAYAKWELVQLYLKEVRQMDKQRTEVIKRVADEISLVIQRDESHNPKRLWQLERANSYGTFRNVLRLIIKDRIKNGAERPLFSIEDYTERLFPDGALCWRETQDLILFRLYEMLHGWLKERDIVIDEVEENSTTEIE
>NC_010803.1|WP_012465414.1|491386_492178_+|nucleotidyl-transferase-AbiEii/AbiGii-toxin-family-protein
MAIDFENDELYAACKAVEPFLDRLVLVGGWAFRALMNIWRKEERETKDTDFAVELVSREAFQEISNHLLANGFKHRNVSDKLKKRKILEYSFEQQDKWIEILPVGEFARDITDLDLKEYRLAFDDNEMLNVRNAAGDALSLKVVHVCSLVVMKVFSYTDRWDERRKDLTDLEYLTEHYGVENDKYGLTVKLKEWFEEKNVPYEMASSHLLGREIQKKLQDELFIETEKRLIKIIERISDSEREETALTKRLNILLEYFQDKYE
>NC_010803.1|WP_012465413.1|490314_491397_+|hypothetical-protein
MEKERLYNITTLFKEKILNVLGWQLKNEPLLKEAEGILFLMVETGKKVLKVGVEYRKTLLRTTSSSFLPDEVDIVMVAAPYIGYAQLERLKANNVNAIDEAGNYYFSYRSGKDRVILYEFNHRSKATRLSRIDAFSPKAGYVVMALLTAERFEISTMRKLQAITEVSLSGIFSICEAMKRNDLIDYSKSLPIRVLNPSRFLDEWAAYFKQRLAPKLNRQGYLISVKKIVDKESREVDVQHLDWREGASVLLDQIQSSALTGVQAAQSVSRFYAVEVGEILVSHLHEAERELTRKFILTPMIRNPNLILIEPYNSSAFIGINEEGKFRKAHPIQIYLDLLTSDDPRANEFAEIYREKALGY
>NC_010803.1|WP_190275093.1|489490_490213_+|CRISPR-associated-endoribonuclease-Cas6
MIYSTLSKSSSEFATVLHDKGYAPEGSRQKFKYFTFSSLQIPIRTIDSGEIVSRSRQITFYLSSPKEEFLQHLILGLFAEGSLRIHNAVFSKECIEKLPEPEWTENMTFSMLSPLAVSVYRDPSAGMNTKEYLRYDDSRLSDMLLHNLQAKYRGLFGCEPPENDIPFSVRFEEAYLKRVREKGRSVEKLITIKDYSGKETRVKAIQCPFTVTGDPELIKVGYECGFGENNPMGFGMVKVS
>NC_010803.1|WP_012465422.1|508432_510424_+|DUF2934-domain-containing-protein
MQICNEEPIRTLAYQLWLDRGAPFDNTQDIDWLESERIILSRSIDPVIDPVVIEPDETDSSAVVPAPPEVTGPAGRTNRWMQAHWERIGRKPLKELCLPSTHDSGTYRLDLKLAPDAADLIKTLYDYADTDNNATGVRKYIRGMAVCQSLTIREQLDSGIRVIDLRVCKVDGVYYCCHALLGDEIRVLLKDMAEFLAANPYEVVFVKVGLKKMSDAEETEAWSYLVENTAPYGIKYPKDKVEGDKSPIDPDFSMETLASLKANKDRRCLLLSDDYFLSNYSDEITTTDGVISRLESKTTDIDGEERANREAKRESGKPTAIDRRLFEAQCFRPTSSFNYGAGYIQAEGAISLGALAGLAGLSLNYVPLLKTVFKGDEHTPVPANLHENAQNSRSIVREYFTWLAGNPHIARPQVINCDYFQEVPLVDIAIQISIGQPVPDLSGVQDIPVPELRMDWFTATVGWVPNLVAFAAMLAGVGCCDLGRYLDDNIPGITGDVLGAALKGAGYACGEVAQTIHTVLKLTADELNTVLRQIGYASDEIEQAFVTMGEGFVDFFSDAGEEAERIAIEAARLAEEAARQTENAARIAAAETARVAEEAARQAEEAALIAAREAERIALETARVAEEAARATAREAERIAREAARVAEDAARATANALNPTRW
>NC_010803.1|WP_012465424.1|510630_510876_+|hypothetical-protein
MKDIHAFVVQLNDAAFRREIAVSFSQLEEGDWNGVVQLAAHYGYTFGMADLKKIAEANPGFFRGSGKNPSLGWDVSALSLL
>NC_010803.1|WP_012465425.1|510982_512656_+|class-I-SAM-dependent-methyltransferase
MHACAEPSLRFPGTFFHGAPQLHAEWSLRISETEIDERSRITFWIASGSAADEEPGFPSIERLLEAIGAPEAVRERQKILSPDCIWQGFGASSGTPDREYALYLHHSDTKTGEVRYDACKWGAEGVVESSRYEFFFFPCAPDGRRPSGFIHPRLSGTFDGLVGNRRLQSMSGFWLRHRHSQTDQVDLVFPWHPPLQLLFDVLKRTDFVSAAALDALMAYRSHPVRHVAFSAANGSEPVITVYFSAPLSGDWPRDFPSLQEAIRISGNALHDALEERIFAHIPQCSASGPDAFLDTFYSTGSVDTWRRVLGANMHYHFGMFSKEEREGSLNIFSDEPFERAVTDLFDCIPYGSSVYDVGCGWGGPARRLSRDHGCRVLGCTISETQYRYLFASGLQVRYADAETTLPPGFFDCMLLLESLEHVRDKAGLLGRLRLFGNKLVMRVHCQDGAPNSVNFAGTMHMIRSTELRGMIEEAGWHIVHWRNRREESMPSLRVWHERLAQIPPGRDVHLETFRSFCSRVCQCEEEWAASNPLIEVVSLREPSVLQSTAAGAGSRLL
>NC_010803.1|WP_012465426.1|512844_513864_+|6-phosphofructokinase
MTDKNNVPNVSQKRVKLRRIGVFTSGGDAPGMNAAIRAVTRAAIANKLKVVGIRRGYQGMIEGDFIPLKSADVSGIIQLGGTILKTARSAEFRTPEGREKAWLQLQKADIDAVVVIGGDGSFTGALTMSQEYNISFVGIPGTIDNDMYGTDYTIGYETALNTVVCAVDKIRDTAVSHGRIFLVEVMGREAGLLALNSGIACGAEVILIPESKEQHDELKRFLDKGYKNKERSGIVIVAEGDEPGGALKIAEAVGRDHPDLDVRVSILGHIQRGGSPTANDRINATRMGIAAVDALLDDQKSVMIGLDNGKIVQVPFNKAVKLNHSIDTGLLDIQKMLSM
>NC_010803.1|WP_012465427.1|513898_514474_+|HD-domain-containing-protein
MRNWRVRSGRIAPASVFEPRLLDGLMASWREVLGEDYEAYRNHCRRVFNFCFALSGSRPEQEEKIAVAAVFHDLGIWSAATFDYLAPSQELARDYLESLGKTEWQEEIAAMIGEHHKLTPVKRNPLWLAEPFRRADLIDISIGLIKFRLPDDFVAEVLDAYPNAGFHKKLLALSFERFMSHPFNPLPMVKL
>NC_010803.1|WP_150081512.1|514487_515207_-|DUF1003-domain-containing-protein
MKTAATEPSHPAHAASCQICGTMQYPRLRRAITVRPAVSELIRRETGSWDENGWICLDDLQLYQHRYIQQLLETEKGELSQLDHDVLRAMKEQELLSKNPDIDFDAELTFGQRLADRIATFGGSWYFIIIFGLFLFLWMGLNSWLLVARPFDPYPFILLNLVLSSLAAIQAPLIMMSQNRQEARDRARAIHDYQVNLKAELEIRQLHQKIDHLLSRQWERLVEIQEIQMELINDIRNRK
>NC_010803.1|WP_012465429.1|515187_518043_-|excinuclease-ABC-subunit-UvrA
MQFSHISIRGARVHNLKNISLDIPRNRFVVITGISGSGKSSLAFDTIFAEGQRRFMETLSPYARQYIGNIERPDVDFIEGLSPVIAIDQKSTNRSPRSTVGTITEIHDFIRLLYAKAGRRYDPVTGHMLQKQSPESIVEAILSLPEGTKVRILSPLVTGRKGHYRELFERLLLKGFVRVRIDGEEQEMEKNMQIERYKTHTIELVVDRLAVGTESADRLKQAVEMAISMSEHRSSVICAPLDTDIKELFFSTQYAYSDGSVPIDTLAPNQFSFNSPYGACPECNGLGELMQLSGDLMIPDPSLSLNQGAIEPFGKPGKRNLWQIIKAIAKQFKFTLDTPISEIPPKALDTLLHGSGSRTFDVIYAYAGKEHGYPQIFQGAIPYVDEMLRNSSSSKMREWTESFMVHQPCPLCKGARLRQESLAVKINGLNIAEAESLPLPEALDFFRELPPVLTGREQLVATPVLHEITKRLEFLLDVGLSYLTLARNARTLSGGEAQRIRLASQLGSQLSGVLYVLDEPSIGLHQRDNHKLIASLQHLRDIGNTVLVVEHDKDTMLMADEIIDLGPGAGEYGGEIVAKGPASQLGPDSLTAAYLTGRKTVFFEPESKEKTGKQQYITIKGCRGNNLRNIDVRFPLGSLISITGVSGSGKSTLINETLHPVLARHFYRSKLISQPYSVIQGIDLIDKVVNVDQTPIGRTPRSNPATYTGAFTFIRDFFTRLPEAQIRGYKAGRFSFNVKGGRCEVCQGAGTMKIEMNFLPDVYVPCENCKGQRYNRETLQVKYKGKSIADVLEMPIEEASGFFEEFPRIRRILSTMESVGLGYLKLGQPSPLLSGGEAQRIKLSAELAKIQTGKTLYILDEPTTGLHFQDIQHLLEVLRKLVDKGNTVIIIEHNLDIIKNSDWVIDLGPEGGSGGGQLVAEGTPTEIAALAHSYTGNFLKIELESHENSSN
>NC_010803.1|WP_012465430.1|518289_518454_+|hypothetical-protein
MDFIYQKQAEKGKQCQECQGFVVKPDNVAEGLCNGKDVLAEGGCMFFKPKEEQQ
>NC_010803.1|WP_012465431.1|518554_521305_-|pyruvate,-phosphate-dikinase
MPEPDFAKATSDAKQYLYSFAGGSAEGDASMKNLLGGKGANLAEMANIGLPVPPGFTISTEVCTYYYDHQKTYPENLFEQDIPASLRKVEQELGKKFGDPENPLLVSVRSGSRASMPGMMDTILNLGLNSETVEGLARKSGNARFAWDCYRRFVQMYGDVVLELKPTDKKQIDPFEAILEAKKHELGIALDTDFSVDDLKEIVAKYKAAIFEKTGKNFPENPYEQLRGAIGAVFNSWNNERAVVYRKLNHIPGYWGTACNVQAMVFGNMGLDCGTGVAFTRDAATGDDIFYGEFLMNAQGEDVVAGTRTPLKIEQLKAENPEIYNQLEDIRSILEKHYRDMMDIEFTIESNKLFMLQCRVGKRTGVAAIKIAVDMFNERLISEKEAILRIEPEQLNQLLRPVFDLKAKKQAIENGRLLATGLNAGPGAATGKIYFNAADAADASKRNEPVILVRIETSPEDIKGMAVSEGILTERGGMTSHAALVARQMGKVCVAGCGALTIDYQKGEMRVNGSDIVLREGDYLSIDGSTGEVIAGEVPTKNSEIIEVLIDKTLKPEDAPTWAIYNQLMEWADRYRKLNIRTNADQPDQAETAITFGAEGIGLCRTEHMFFGGERIDAMREMILADDIEGRKTALDKLLPYQRDDFYGLFKAMGSRPVTIRLLDPPLHEFLPHTEGEIADLAAKIGKSVETIRERISDLHEFNPMLGLRGCRLGILHPEIPVMQVRAIIEAACRLKKEGHEVVPEIMVPLVSTVKELEITAEIIHKTARSVIAEQGTGIRYLVGTMIEVPRAAITSDQIARAADFFSYGTNDLTQMGLGMSRDDSGQFLPTYQQQDIFARNPFESIDIDGVGRLMSISAKEGRSVKPDLKLGICGEHGGDPTTVEFCHKTGLNYVSCSPYRVPIARLAAARAALQS
>NC_010803.1|WP_012465432.1|521461_522343_+|ABC-transporter-permease
MGIEFFLFFQQILRIAVPYVLTSVGASFSERGGVVNLALEGMMLAGAFGAAAGQHYTGSAAAGIVFALASGLAVAFLHAFVTVTMKADQIVSGIAINILVMGATRFGLSVLFGSAMNSARIGGIEVSSVFADPLFLAALFSVFAGQFVLFGTPYGLRLRATGESAETADAAGIRVGAMRYSGVLLSGALAALAGAFLVFQQHSFTDGMTAGRGYIALAAMIIGKWNPVGAALASLMFASAEAAEMWLQSGFLPTQLVQSLPYVITLFVLAGFVGKAVAPREVGVPYVKSLRSD

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Crispr_ID: NC_010803_3

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_010803_3

583684-583772

Orphan

Consensus_repeat	Method
GAAGCAGCACCTGCAACAGAAGCAGCACCTGC	CRISPRCasFinder

1 spacers

The CRISPR arrays of NC_010803_3

>merge|NC_010803|3|583684-583772|CRISPRCasFinder
GAAGCACCTGCAACCGAAGAGGCTGCACCTGCAGCAGAAGAAGCAGCACCTGCAACAGAAGCAGCACCTGCAACCGAAGAAGCAGCTCC

>NC_010803|3|3|583684-583772|CRISPRCasFinder
GAAGCACCTGCAACCGAAGAGGCTGCACCTGC	AGCAGAAGAAGCAGCACCTGCAACA
GAAGCAGCACCTGCAACCGAAGAAGCAGCTCC

Protein	Signature genes	Signature genes Name	Protein_function
NC_010803.1\|WP_012465496.1\|591265_591820_+\|hypothetical-protein	unknown	unknown	unknown
NC_010803.1\|WP_041465848.1\|591819_592668_+\|NAD+-synthase	unknown	unknown	gnl\|CDD\|184435
NC_010803.1\|WP_012465494.1\|588242_589517_-\|UDP-N-acetylglucosamine-1-carboxyvinyltransferase	unknown	unknown	gnl\|CDD\|236486
NC_010803.1\|WP_012465498.1\|592788_594384_-\|L-aspartate-oxidase	unknown	unknown	gnl\|CDD\|236374
NC_010803.1\|WP_012465488.1\|580888_583459_+\|bifunctional-aconitate-hydratase-2/2-methylisocitrate-dehydratase	unknown	unknown	gnl\|CDD\|236424
NC_010803.1\|WP_012465492.1\|586065_586359_+\|H-NS-histone-family-protein	unknown	unknown	gnl\|CDD\|376390
NC_010803.1\|WP_012465480.1\|571983_572442_+\|phosphate-starvation-inducible-PsiE-family-protein	unknown	unknown	unknown
NC_010803.1\|WP_012465479.1\|571353_571764_-\|acyl-CoA-thioesterase	unknown	unknown	gnl\|CDD\|223894
NC_010803.1\|WP_012465483.1\|574438_575644_-\|methionine-adenosyltransferase	unknown	unknown	gnl\|CDD\|235298
NC_010803.1\|WP_049754277.1\|572549_573362_+\|copper-resistance-protein-NlpE-N-terminal-domain-containing-protein	unknown	unknown	gnl\|CDD\|377235
NC_010803.1\|WP_012465495.1\|589709_591260_+\|peptidoglycan-DD-metalloendopeptidase-family-protein	unknown	unknown	gnl\|CDD\|366703
NC_010803.1\|WP_012465493.1\|586946_587846_-\|auxin-efflux-carrier	unknown	unknown	gnl\|CDD\|223751
NC_010803.1\|WP_150081518.1\|585463_585691_-\|JAB-domain-containing-protein	unknown	unknown	gnl\|CDD\|377189
NC_010803.1\|WP_012465499.1\|594405_595020_-\|VTT-domain-containing-protein	unknown	unknown	gnl\|CDD\|182775
NC_010803.1\|WP_012465486.1\|578272_579559_+\|histidinol-dehydrogenase	unknown	unknown	gnl\|CDD\|234853
NC_010803.1\|WP_012465485.1\|576980_578009_-\|rod-shape-determining-protein	unknown	unknown	gnl\|CDD\|237564
NC_010803.1\|WP_012465487.1\|579555_580587_+\|tRNA-preQ1(34)-S-adenosylmethionine-ribosyltransferase-isomerase-QueA	unknown	unknown	gnl\|CDD\|234666
NC_010803.1\|WP_150081515.1\|584597_584801_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|271182
NC_010803.1\|WP_041465847.1\|575818_576958_+\|N-acetyl-alpha-D-glucosaminyl-L-malate-synthase-BshA	unknown	unknown	gnl\|CDD\|274914
NC_010803.1\|WP_012465482.1\|573450_574425_+\|calcium/sodium-antiporter	unknown	unknown	gnl\|CDD\|182684

Protein	Function_ID	Function_description	E-value
NC_010803.1\|WP_041465848.1\|591819_592668_+\|NAD+-synthase	gnl\|CDD\|184435	PRK13980, PRK13980, NAD synthetase; Provisional.	2.40608e-156
NC_010803.1\|WP_012465494.1\|588242_589517_-\|UDP-N-acetylglucosamine-1-carboxyvinyltransferase	gnl\|CDD\|236486	PRK09369, PRK09369, UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Validated.	0
NC_010803.1\|WP_012465498.1\|592788_594384_-\|L-aspartate-oxidase	gnl\|CDD\|236374	PRK09077, PRK09077, L-aspartate oxidase; Provisional.	0
NC_010803.1\|WP_012465488.1\|580888_583459_+\|bifunctional-aconitate-hydratase-2/2-methylisocitrate-dehydratase	gnl\|CDD\|236424	PRK09238, PRK09238, bifunctional aconitate hydratase 2/2-methylisocitrate dehydratase; Validated.	0
NC_010803.1\|WP_012465492.1\|586065_586359_+\|H-NS-histone-family-protein	gnl\|CDD\|376390	pfam00816, Histone_HNS, H-NS histone family.	1.11047e-14
NC_010803.1\|WP_012465479.1\|571353_571764_-\|acyl-CoA-thioesterase	gnl\|CDD\|223894	COG0824, FcbC, Predicted thioesterase [General function prediction only].	3.01501e-31
NC_010803.1\|WP_012465483.1\|574438_575644_-\|methionine-adenosyltransferase	gnl\|CDD\|235298	PRK04439, PRK04439, methionine adenosyltransferase.	0
NC_010803.1\|WP_049754277.1\|572549_573362_+\|copper-resistance-protein-NlpE-N-terminal-domain-containing-protein	gnl\|CDD\|377235	pfam04170, NlpE, NlpE N-terminal domain. This family represents a bacterial outer membrane lipoprotein that is necessary for signalling by the Cpx pathway. This pathway responds to cell envelope disturbances and increases the expression of periplasmic protein folding and degradation factors. While the molecular function of the NlpE protein is unknown, it may be involved in detecting bacterial adhesion to abiotic surfaces. In Escherichia coli and Salmonella typhi, NlpE is also known to confer copper tolerance in copper-sensitive strains of Escherichia coli, and may be involved in copper efflux and delivery of copper to copper-dependent enzymes.	2.29068e-34
NC_010803.1\|WP_012465495.1\|589709_591260_+\|peptidoglycan-DD-metalloendopeptidase-family-protein	gnl\|CDD\|366703	pfam01551, Peptidase_M23, Peptidase family M23. Members of this family are zinc metallopeptidases with a range of specificities. The peptidase family M23 is included in this family, these are Gly-Gly endopeptidases. Peptidase family M23 are also endopeptidases. This family also includes some bacterial lipoproteins for which no proteolytic activity has been demonstrated. This family also includes leukocyte cell-derived chemotaxin 2 (LECT2) proteins. LECT2 is a liver-specific protein which is thought to be linked to hepatocyte growth although the exact function of this protein is unknown.	8.15559e-27
NC_010803.1\|WP_012465493.1\|586946_587846_-\|auxin-efflux-carrier	gnl\|CDD\|223751	COG0679, COG0679, Predicted permeases [General function prediction only].	3.35832e-15
NC_010803.1\|WP_150081518.1\|585463_585691_-\|JAB-domain-containing-protein	gnl\|CDD\|377189	pfam04002, RadC, RadC-like JAB domain. A family of proteins present widely across the bacteria. This family was named initially with reference to the E. coli radC102 mutation which suggested that RadC was involved in repair of DNA lesions. However the relevant mutation has subsequently been shown to be in recG, where radC is in fact an allele of recG. In addition, a personal communication from Claverys, J-P, et al, indicates a total failure of all attempts to characterize a radiation-related function for RadC in Streptococcus pneumoniae, suggesting that it is not involved in repair of DNA lesions, in recombination during transformation, in gene conversion, nor in mismatch repair. Computational analysis, however, provides a possible function. The RadC-like family belong to the JAB superfamily of metalloproteins. The domain shows fusions to an N-terminal Helix-hairpin-Helix (HhH) domain in most instances. Other domain combinations include fusions to the anti-restriction module ArdC, the DinG/RAD3-like superfamily II helicases and the DNAG-like primase. In some bacteria, closely related DinG/Rad3- like superfamily II helicases are fused to a 3'-5' exonuclease in the same position as the RadC-like JAB domain. These conserved domain associations lead to the hypothesis that the RadC-like JAB domains might function as a nuclease.	2.14519e-07
NC_010803.1\|WP_012465499.1\|594405_595020_-\|VTT-domain-containing-protein	gnl\|CDD\|182775	PRK10847, PRK10847, DedA family protein.	9.85214e-48
NC_010803.1\|WP_012465486.1\|578272_579559_+\|histidinol-dehydrogenase	gnl\|CDD\|234853	PRK00877, hisD, bifunctional histidinal dehydrogenase/ histidinol dehydrogenase; Reviewed.	0
NC_010803.1\|WP_012465485.1\|576980_578009_-\|rod-shape-determining-protein	gnl\|CDD\|237564	PRK13930, PRK13930, rod shape-determining protein MreB; Provisional.	0
NC_010803.1\|WP_012465487.1\|579555_580587_+\|tRNA-preQ1(34)-S-adenosylmethionine-ribosyltransferase-isomerase-QueA	gnl\|CDD\|234666	PRK00147, queA, S-adenosylmethionine:tRNA ribosyltransferase-isomerase; Provisional.	6.23419e-169
NC_010803.1\|WP_150081515.1\|584597_584801_+\|hypothetical-protein	gnl\|CDD\|271182	cd00801, INT_P4_C, Bacteriophage P4 integrase, C-terminal catalytic domain. P4-like integrases are found in temperate bacteriophages, integrative plasmids, pathogenicity and symbiosis islands, and other mobile genetic elements. The P4 integrase mediates integrative and excisive site-specific recombination between two sites, called attachment sites, located on the phage genome and the bacterial chromosome. The phage attachment site is often found adjacent to the integrase gene, while the host attachment sites are typically situated near tRNA genes. This family belongs to the superfamily of DNA breaking-rejoining enzymes, which share the same fold in their catalytic domain and the overall reaction mechanism. The catalytic domain contains six conserved active site residues. Their overall reaction mechanism involves cleavage of a single strand of a DNA duplex by nucleophilic attack of a conserved tyrosine to give a 3' phosphotyrosyl protein-DNA adduct. In the second rejoining step, a terminal 5' hydroxyl attacks the covalent adduct to release the enzyme and generate duplex DNA.	0.000702233
NC_010803.1\|WP_041465847.1\|575818_576958_+\|N-acetyl-alpha-D-glucosaminyl-L-malate-synthase-BshA	gnl\|CDD\|274914	TIGR03999, thiol_BshA, N-acetyl-alpha-D-glucosaminyl L-malate synthase BshA. Members of this protein family are BshA, a glycosyltransferase required for bacillithiol biosynthesis. This enzyme combines UDP-GlcNAc and L-malate to form N-acetyl-alpha-D-glucosaminyl L-malate synthase. Bacillithiol is a low-molecular-weight thiol, an analog of glutathione and mycothiol, and is found largely in the Firmicutes. [Biosynthesis of cofactors, prosthetic groups, and carriers, Glutathione and analogs].	0
NC_010803.1\|WP_012465482.1\|573450_574425_+\|calcium/sodium-antiporter	gnl\|CDD\|182684	PRK10734, PRK10734, putative calcium/sodium:proton antiporter; Provisional.	9.30512e-81

>NC_010803.1|WP_012465488.1|580888_583459_+|bifunctional-aconitate-hydratase-2/2-methylisocitrate-dehydratase
MSLVSQYRAHTEERALLGIPPLPLTADQARSLIGLLQQQPVEEKEYLLELFCEHVSPGVDDAAFEKAAFLDAVIKGESICEVITPVEAVRILGTMLGGYNVKPLIDALSHKDTEVCTTAAAMLRNVLLVYDSFDAVAGLSATNAYAKEVLQSWADAEWFTSRPVLPEKMTLTVFKVPGETNTDDLSPASEAFTRSDIPLHALCMLGSKMDDPIGTIAALKEKGHPLAYVGDVVGTGSSRKSGINSVQWHLGEDIPAVPNKRTGSVIIGSIVAPIFFNTAEDSGALPIQADVSAMETGDVIDVYPYEGKIEKDGEIISRFDLTPNTLTDEVRAGGRIPLIIGRTLTKKARTFLGMGEDSLFINPLQPADSGKGYTLAQKMIGKACGLPGVRPGMYVEPETLTVGSQDTTGAMTRDEVKELAALSFSADLVMQSFCHTAAYPKPSDVKLHRTLPYFIMSRGGVSLRPGDGVIHTWLNRMVLPDTLGTGGDSHTRFPIGVSFPGGSGLVAFAAVTGTMPLNVPESVLVRFSGTLQEGITLRDLVNAIPYVAIRQGLLTVEKKGKKNIFAGRILEIEGLPQLKVEQAFELSDASAERSAAACTVRLDKEPVIEYLSSNMKLLEQMIEEGYGNPETLRRRISRMQEWLDNPVLLQPDSDAEYAAVIEIDLNTITEPVLACPNDPDDVMTLSEILLDENRPKKIDEVFVGSCMTNIGHFRALGEVLRNKGVASARLWIVPPTKMDMKKLVEEGYYSVFGAAGARMEIPGCSLCMGNQARVADNAVVFSTSTRNFDNRMGKGAKVYLGSAELAAVAALLGHLPNRDEYMEVVRKQLSGAREEEIYRYLNFHELGKEDLQLLVD
>NC_010803.1|WP_012465487.1|579555_580587_+|tRNA-preQ1(34)-S-adenosylmethionine-ribosyltransferase-isomerase-QueA
MKVSDFDYTLPEDMIARYPPAERGTTRLLVLDPATGETEHSRYAHLADFLKPGDLLLLNNSKVVRARMFASKKTGASIELMLLEKHEGVQNLVLYRGRLKKGDRLIAHSEELLVEEITGQGVARLSASDGSDLPHLFERHAEVPIPPYLKREAEAVDAERYQTVFAEQPGSVAAPTASLNMTAGLLAELGQKGIDTATVTLHVGLGTFLPIRVESFEEHVMHREYYSIPFRTIDKIRRTKAGGGRVVAVGTTVTRALEHAAGSSCWGTSVAPASGEADIFIYPGYRFRVIDALLTNFHAPRSTVLMLTAAFAGQQNLLSAYHEAIEKQYRFLSYGDSMLIRPM
>NC_010803.1|WP_012465486.1|578272_579559_+|histidinol-dehydrogenase
MLNIYRYETDREALKKQLERSVTFEPEVERTVHDILAAVRSGGDKALLDYTERFQGVRLQEMTVSGEEIRRAYEQADSRFIGVLEEAYRNITAFHRHEIEKSFFYEAEGGVILGQRVTPMERAMLYVPGGKAAYPSSLLMNAAPAQVAGVGQIFLTTPCDSEGNVSSHILAAAAVAGIGSVYKLGGAQAVAAFAFGTESIPKVDSITGPGNKYVALAKKQVFGHVAIDSIAGPSEVVIIADESADPDFIVLDMFAQAEHDPDASAVLITPSESLADAVRQRAANRIETMLRKEVIAASLSSNGAVVITGSMEEACRVSDSLAPEHLELHVENPWDLLGSIHHAGAIFMGAYSCETVGDYFAGPNHTLPTNGTARFFSPLSVRDFIKHTSIISYSRRQLLSCGEKIASFADHEGLQAHAEAVRERLRKA
>NC_010803.1|WP_012465485.1|576980_578009_-|rod-shape-determining-protein
MSFFSSLFRDIAIDLGTANTLIYIRDKGVVLNEPSIVARERNTGKVVAIGHDALLMHEKTHPGIITIRPLANGVIADYEATEELIRGLINKTKTQFSFGIRRMVIGIPSGITEVEKRAVRDSAEHVGAKEVYLVAEPMAAAIGIGIDVKEPMGNMIVDIGGGTTEIAVISLGGIASGESLRVAGTDITNSIVRHFRKAYNLAIGERTAEDVKIKIASAYKLDKELTMNVRGRNLVTALPEEREINSPTIREAIATPISQIITSIKKSLEVTKPELSADILDRGLFLAGGGALIKGLDKKINEETKLAVHISEEPLTAVARGTGEVLENLEKYRSVLLSTKRY
>NC_010803.1|WP_041465847.1|575818_576958_+|N-acetyl-alpha-D-glucosaminyl-L-malate-synthase-BshA
MKIGISCHHTYGGSGAIAAELGKALAGRGHIVHFFSQAAPFRLGTFSKNIFYHEVEAMHYPLFECPFYSLALASKIAEVAFYEKLDVVHAHYAIPHALSAMLARQMLEDKCAEARCFRLATTLHGTDITVVGADSGMQDVVRLAINKSDGVTAVSGYLRDETNRMFSPKKEITVIPNFVDTSVFFRSPDQDLRGHLRLGNDKIVIHISNFRPVKCIGDIVRVFHALTAHIDVTMLFVGDGPERSAAELRVRELGIADRVRFLGKIDEIVPLLSLADIMLMPSNVESFGLAALEAMACGVPVIATDAGGFPEFVVPGLHGYLLPPGDIEGMTEKALLLLSDEPHRQACSEACIQQAKRYETALLVERYEAYYTGLITGMA
>NC_010803.1|WP_012465483.1|574438_575644_-|methionine-adenosyltransferase
MRTISVEKAAEPSVSERQTELVERKGTGHPDTICDSVMEASCIRLCREYIERTGRILHHNLDKGLLIAGRTLTKPGGGSVLEPMRLISGDRATMSWKGIDIPVDEIVETAAKEWIAGNLRFVDPEKHIVFQHEIRTGSAELSDAFSRPVIGANDTSVGVGYAPLSETESTVLETERYMNSSACKSIFPETGEDIKIMGFRNGNSLDLTIAIAFIDRFISDAADYFSRKLALKEHLERYLLNRTSSFEKVSLRINALDDPRREEGGMYLTVLGTSAEGADGGEVGRGNRVNGLIAFGRPSSLEAAAGKNPVSHVGKIYNVLARETAARIHREVPGVKEVTVFFCSRIGTPVDQPLVASARIIPDSGNRFGPMQREASAIIESELNGMRVFLDRLALGRFPVC
>NC_010803.1|WP_012465482.1|573450_574425_+|calcium/sodium-antiporter
MLLFLLSVVVGLVLLVWSAGRFVDGSAAAARHFRMPPLLIGMVIVGFGTSAPEMSVSAISASQGNPDIALGNVFGSNITNIALILGLTALLSPIAVHSRVLRKELPVLTIMTAIAAFLMYDGMFSRQDATFLLLLFALLMGWTVWEGIMKSGDEFAVEMENELEQHPMPLGKALLLVAAGLLLLLVSSRMLVWGAVGIAGALGVSDIVIGLTVVAVGTSLPELASSLAAVRKGEHDIALGNVIGSNLFNILAVAGVAGAIYPAVIDPAVFLRDIMIMLLLTVSLFVVGYGFRGEGTGRINRIEGMILLGSYAAYTIYLVSTNFG
>NC_010803.1|WP_049754277.1|572549_573362_+|copper-resistance-protein-NlpE-N-terminal-domain-containing-protein
MKNAKVFLFFASVMLLMSSCMRHTKTDHAAEGRPAGDNSRVSLDWEGTYRGILPCADCQGIETTVTLDKNGTCLIRSRYLAKSDRIFSEACTFVWDREGRTISVSGKESAPRRYLVGENMLVQLDMQGKRITGLLADKYVLGKVVSSEAMVPDASLGETYWKLVELNGKPLKQLPFRQQEAHMILKKADGRVQGSGGCNRFFGRYETRPGNRIHFSGLGSTMMACPGLAEESAFFKVLETADTYTIRGESLQLHKARMAALAKFEAVYLK
>NC_010803.1|WP_012465480.1|571983_572442_+|phosphate-starvation-inducible-PsiE-family-protein
MKIRFEAYLLQVLHGFNHFLHALVAIALVMASLMVVWEFSVAVMHSFEKNDLAHGFLQALGSLFIVWTLSSLIAAEINYVQTGVFHVEVFIEVAMITLLRQLIVEPVNVATGAQNLESIFNAWHYGLLLSALLVTGILHKLVTSSDKKKENV
>NC_010803.1|WP_012465479.1|571353_571764_-|acyl-CoA-thioesterase
MSTEGTRFSISMEVRPEDIDLMGHVNNTVYLRWVQDAAVAHWHILAPAEERETILWVVRRHEIDYKRPAFSGDTLKVETWIGKATRFAFDRHTTIINVSSGRILALARTVWCPIDRKTGKPADVSPAVRDIFSIPA
>NC_010803.1|WP_150081515.1|584597_584801_+|hypothetical-protein
MQVTSESVTVSRHSPPDHLRHTRSTRMRESGLRPDIVEAIIDHHDSGIIGSYGSYSRHPGMKSAIIR
>NC_010803.1|WP_150081518.1|585463_585691_-|JAB-domain-containing-protein
MKWSAQYVELIPDTSRRAALLCNAHAVFLAHTHPSGVSEPGNAYKKGNSITCKILKHDGGSSTRSGYLRKYWMLF
>NC_010803.1|WP_012465492.1|586065_586359_+|H-NS-histone-family-protein
MQTIAELQAQMASIQKQINEQKAAGKRDALADILSKMNEFGITIHEIQRRIVPVKAKAAKTVKYRLEDKTWSGKGKKPKWVKNIEERGGRLDDYLVA
>NC_010803.1|WP_012465493.1|586946_587846_-|auxin-efflux-carrier
MFDVFFLLAPVFSLFFLGILLRKTGIIDEKGASFLFGFIHKLTLPTLALSLFPYVTLSTGMLAVPLISILVTAAMPVGAIAAKKLLHLPDQTFAAILNGSILMNTSFMLPFVKPLFGAEGVALLFLFNAANTLTANFFLGILQSSRYTDGTTQIATNGFSFLPLTIPAIVCGIAMNLLHLSFVPVTAVILHDIGELTIPLLLLASGASVKLPKVDMIHLFSGITIRMAGGAATGLGVAAFFGLEEPGRSVLALCAAAPAALIRPGTQSAESPENSFSEAFASTGMLGAMILIPLLLLLL
>NC_010803.1|WP_012465494.1|588242_589517_-|UDP-N-acetylglucosamine-1-carboxyvinyltransferase
MDKLVIRGGRRLIGSVTASGSKNSSLPVIAATLLSGNGTFTLHRIPDLQDISTFTQLINHLGAQTSFSDNTLTVSTGNVESLLAPYELVKKMRASIYVLGPLLARFGEATVSLPGGCAFGPRPIDLHLMAMEKLGAEITIETGFITAKARNGKLQGARIDFPVSSVGATGNALMAAVLAEGKTIITNAAAEPEIEALCRFLASMGARIEGTGTTELIIEGVTSLSAVEFTNVFDRIEAGTLLAAAAITGGTVTVDGVEPEQLKSVLKKFAHAGCTISQTPGSITLASPEKLIPTDITAKPYPSFPTDMQAQWTALMTQAEGTSRITDKVYHERFNHIPELNRLGAHIEIRKNQAIVEGPRRLSGTKVMSTDLRASACLVLAGLVADGVTEVLRVYHLDRGYEQIEMKLNSLGADITREKYKEFS
>NC_010803.1|WP_012465495.1|589709_591260_+|peptidoglycan-DD-metalloendopeptidase-family-protein
MPLTKKKNLLRNFCSGRSIGLLLLLLLGLVPAGAAVSAPAANTEILKIKKERQNVELTLKKLKKQLEEYQAKISTTKKQESQSLKALENIRRQILVLEKLIRENQSYLVVLDDDIDSLNGALHTNRRTYARVSDDFRRTAVSVYKHGRQRDTEQLFSSGSVNEALLRSKYMGFFSRAVRGDVEKLQYVAVQLENNRAELQKSYQEKAAVVRDQEQQLKTYSQKGKEKEVVLEKLRQNKKQYGAQLATVMSKRRQLQSKIEGLIFAEQRAVAEEKERQRRIQEARRLEAQRLEAQRLEAQRQEARRAEAQRLERERLQGQQQGSGSRQKDAAEPVAEKTDQAVQRKSAVKKTSKRKPESRLASRNEASVVPDVSSQEIEKVSADFDRAFGSLPWPVRGGVVAERFGSVEDRDLRIVKTNNGIDISVPVGTSVRAVSGGKVVQIAFLPTFGNIVIIRHPNSYLTVYANLGSLSVAKNELIRSQQMIGVSGKMPEGGSVVHFEIWKGKVKQNPEKWLRR
>NC_010803.1|WP_012465496.1|591265_591820_+|hypothetical-protein
MSIKKLFSTIIALLFSHRQFWEDYRSGKAGVVDNVLKDYAVPVIALVQLVKFPLIGIPRQAMIIAIATFLVDVAALYLITGGIMRFFDGAPQNRQEQMITAVIGFSLTPVWLAEPFYFLGSWSWVFASAAILFSLFISGNGFSLLFDRINQSAMRNSALLLVTVCVAVFVVERGMLRLFNGFSL
>NC_010803.1|WP_041465848.1|591819_592668_+|NAD+-synthase
MPARDLHLDYSLVEDILTSFLRNEVQKFGFRSVAIGLSGGIDSAVVIELAVRAFGAGQVLGVMMPYRSSSPESLEHAELMISRLGVRSEVVDISPAVDAFVRSVPEGDLLRRGNIMARTRMVYLYDISARDCRLIIGTSNKTELLLGYGTLFGDMASAINPVGDLYKTQLRGLARHLGIPEPLIAKVPSADLWEGQSDEADLGFSYEDADSILYMMLEKRMDRQSMLAEGVPAAFYDRVRKMVVSNQYKRMMPVIAKISGRTPGIDFRYARDWQENIVYRKQ
>NC_010803.1|WP_012465498.1|592788_594384_-|L-aspartate-oxidase
MTESLQTDVLVIGSGIGGLYFAIHMADHASVTIITKKESSTSNTNWAQGGIAATIESGDTAELHIEDTLGAGAGLCKRDMVAVMVEEGPQHIRRLMELGVQFTTSDHEQLHLGKEGGHSRSRIVHAQDFTGREVENALLARVNSHPNITLLEHHFAIELLTEHHLGIKTNDITCYGAYVLDSKQRKPKKILAKITIVASGGLGHVYQHTTNPDIATGDGVAMAYRAGAEIANMEFIQFHPTSLYHPKAKSFLISEAVRGFGGILKLKNGQEFMHKYDKRQNLAPRDIVARAIDSEIKKSGEECVFLDVTHIDAAKTREHFPNIYETCLQYGIDMTKEMIPVVPAAHYSCGGIRTDAMGRTTLNRLYACGESSCTGVHGANRLASNSLLEALVFAWRSFTDIREQLPALDNSVKFPDWDDSGTVNPEEWILVSHNKREAQGVMNDYVGIVRSDLRLQRAQRRIEFLKDETEAYYKKTKITTQILELRNIIKVASLIIESAVKRRESRGLHYTTDYPQRDDKHFLIDTVLRSF
>NC_010803.1|WP_012465499.1|594405_595020_-|VTT-domain-containing-protein
MLLIASLQNIRTLDELILWGGYLLLFTIIFAETGLFAGFFLPGDSLLITAGLIAASGRLDITTALATMAAAAVLGDSTGYLIGKQLQKSIFSKKETLFFHRDHLDKTEAFYRKHGAKTIFLARFVPVVRSFAATLAGVAAMPYPVFLFYSLTGAVLWVLCFTLTGYYIASMFPEVVQYLHIFIMVGIVLIVLSALRHLKPGKHS

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Crispr_ID: NC_010803_4

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_010803_4

1009935-1011874

TypeIII

Consensus_repeat	Method
CTTTATATCTAATTGCACTCATTGAGGATTGAAAC	PILER-CR
CTTTATATCTAATTGCACTCATTGAGGATTGAAAC	CRISPRCasFinder
CTTTATATCTAATTGCACTCATTGAGGATTGAAAC	CRT
CTTTATATCTAATTGCACTCATTGAGGATTGAAAC	PILER-CR

26 spacers

cas2,cas1,cmr1gr7,cmr6gr7,cas10,cmr4gr7,cmr5gr11,cmr3gr5

The CRISPR arrays of NC_010803_4

>merge|NC_010803|4|1009935-1011874|PILER-CR,CRISPRCasFinder,CRT,PILER-CR
CTTTATATCTAATTGCACTCATTGAGGATTGAAACTTGCAGGTCTTCCGCCTGCGAGCTGAATCATGTCCCTTTATATCTAATTGCACTCATTGAGGATTGAAACGTTCTTCTTCGATGCGCTGGCGTTCTGCCTCTTCACTTTATATCTAATTGCACTCATTGAGGATTGAAACTCATATTGCACTTTCGGCATTGCCATCCTCCACTTTCTTTATATCTAATTGCACTCATTGAGGATTGAAACAACATCCCTATTGTTTTATCGTACAACTCGTCACTTCTTTATATCTAATTGCACTCATTGAGGATTGAAACTCGGAGACATCCTTGTAAGCCTTCACAACATCATTAAAGTCTTTATATCTAATTGCACTCATTGAGGATTGAAACTTATCTCGCGCCGGACGATGTTGTCACCGCAGTACACCTTTATATCTAATTGCACTCATTGAGGATTGAAACTAGCCGTCGCCTGCCACTATGCTTTCCATACAGGCACCCTTTATATCTAATTGCACTCATTGAGGATTGAAACTATTGTGCAACCCAGATTTCGACACGGCGATTTCGCTCCCTTTATATCTAATTGCACTCATTGAGGATTGAAACAATCTTCAAACTTAATTATTGTTTCTGTTTTATTATATACTTTATATCTAATTGCACTCATTGAGGATTGAAACATGCACGTCTTACTCATACTTCTCCCTCCGTTTTGCTCAATTCTTTATATCTAATTGCACTCATTGAGGATTGAAACCTTCTTCCCGGTCGCAAGGCGTGAGCACCGCCGTCACCCTTTATATCTAATTGCACTCATTGAGGATTGAAACTAATCACACTTCCTGACCGTAGCAGCCAGCGCCCCGTCTGCTTTATATCTAATTGCACTCATTGAGGATTGAAACTTAACTCGATAGCGTATGCAATGGCTACGCAAGGGACTTTATATCTAATTGCACTCATTGAGGATTGAAACTTCCAAATCTCTCATGTTAGCTATGTCCTTATAATCAACTTTATATCTAATTGCACTCATTGAGGATTGAAACCTCAACCCCATGTAAAAAAGACATAAGACATCTATTTAAACTTTATATCTAATTGCACTCATTGAGGATTGAAACGCCACCACTTCAGCCTTATCAGTAATTCCCGTAAGATAAACTTTATATCTAATTGCACTCATTGAGGATTGAAACTACAGGTGGTACACGCCGTCTTTGCGGAGCACTCCCCCGCTTTATATCTAATTGCACTCATTGAGGATTGAAACAACAAATGGAGCTGGGTCGACAACCCGTAGTGCAGCCTTTATATCTAATTGCACTCATTGAGGATTGAAACTAAGCGAATAAACCGCATATAAACCCGCGACCAGCAGGCTTTATATCTAATTGCACTCATTGAGGATTGAAACTTTGGTTCCGGTCTGGTGGTAGCCCATGTATTTGATTGCCTTTATATCTAATTGCACTCATTGAGGATTGAAACTTGCGTCGAAACCTTGTTTCGAAAGTTTTCTCTGAAACTTTATATCTAATTGCACTCATTGAGGATTGAAACTTGATTTAAGCACGCCGGCGTTCAGCAATTGCCCCCCGCTTTATATCTAATTGCACTCATTGAGGATTGAAACTTTCCATTTCCGAAAGTATTTCTTCAGCTTTTTCAAGATCTTTATATCTAATTGCACTCATTGAGGATTGAAACCTTTTGGCTGTTAATGATGCGGTGGGTCTTGCCACAGCTTTATATCTAATTGCACTCATTGAGGATTGAAACCCACCTCTCCCTCGATGCTTACTGCATCACGAGGCGAATCTTTATATCTAATTGCACTCATTGAGGATTGAAACAACCGTTTGATGCTGCTGCAATCGTCATGCCATCACGGAGAACACTTTATATCTAATTGTACTCATTGAGGATATATTT

>NC_010803|4|2|1009935-1011502|PILER-CR
CTTTATATCTAATTGCACTCATTGAGGATTGAAAC	TTGCAGGTCTTCCGCCTGCGAGCTGAATCATGTCC
CTTTATATCTAATTGCACTCATTGAGGATTGAAAC	GTTCTTCTTCGATGCGCTGGCGTTCTGCCTCTTCA
CTTTATATCTAATTGCACTCATTGAGGATTGAAAC	TCATATTGCACTTTCGGCATTGCCATCCTCCACTTT
CTTTATATCTAATTGCACTCATTGAGGATTGAAAC	AACATCCCTATTGTTTTATCGTACAACTCGTCACTT
CTTTATATCTAATTGCACTCATTGAGGATTGAAAC	TCGGAGACATCCTTGTAAGCCTTCACAACATCATTAAAGT
CTTTATATCTAATTGCACTCATTGAGGATTGAAAC	TTATCTCGCGCCGGACGATGTTGTCACCGCAGTACAC
CTTTATATCTAATTGCACTCATTGAGGATTGAAAC	TAGCCGTCGCCTGCCACTATGCTTTCCATACAGGCACC
CTTTATATCTAATTGCACTCATTGAGGATTGAAAC	TATTGTGCAACCCAGATTTCGACACGGCGATTTCGCTCC
CTTTATATCTAATTGCACTCATTGAGGATTGAAAC	AATCTTCAAACTTAATTATTGTTTCTGTTTTATTATATA
CTTTATATCTAATTGCACTCATTGAGGATTGAAAC	ATGCACGTCTTACTCATACTTCTCCCTCCGTTTTGCTCAATT
CTTTATATCTAATTGCACTCATTGAGGATTGAAAC	CTTCTTCCCGGTCGCAAGGCGTGAGCACCGCCGTCACC
CTTTATATCTAATTGCACTCATTGAGGATTGAAAC	TAATCACACTTCCTGACCGTAGCAGCCAGCGCCCCGTCTG
CTTTATATCTAATTGCACTCATTGAGGATTGAAAC	TTAACTCGATAGCGTATGCAATGGCTACGCAAGGGA
CTTTATATCTAATTGCACTCATTGAGGATTGAAAC	TTCCAAATCTCTCATGTTAGCTATGTCCTTATAATCAA
CTTTATATCTAATTGCACTCATTGAGGATTGAAAC	CTCAACCCCATGTAAAAAAGACATAAGACATCTATTTAAA
CTTTATATCTAATTGCACTCATTGAGGATTGAAAC	GCCACCACTTCAGCCTTATCAGTAATTCCCGTAAGATAAA
CTTTATATCTAATTGCACTCATTGAGGATTGAAAC	TACAGGTGGTACACGCCGTCTTTGCGGAGCACTCCCCCG
CTTTATATCTAATTGCACTCATTGAGGATTGAAAC	AACAAATGGAGCTGGGTCGACAACCCGTAGTGCAGC
CTTTATATCTAATTGCACTCATTGAGGATTGAAAC	TAAGCGAATAAACCGCATATAAACCCGCGACCAGCAGG
CTTTATATCTAATTGCACTCATTGAGGATTGAAAC	TTTGGTTCCGGTCTGGTGGTAGCCCATGTATTTGATTGC
CTTTATATCTAATTGCACTCATTGAGGATTGAAAC	TTGCGTCGAAACCTTGTTTCGAAAGTTTTCTCTGAAA
CTTTATATCTAATTGCACTCATTGAGGATTGAAACTTGATTTAAGCACGCCGGCGTTCAGCAATTGCCCCCCGCTTTATATCTAATTGCACTCATTGAGGATTGAAAC	TTTCCATTTCCGAAAGTATTTCTTCAGCTTTTTCAAGAT
CTTTATATCTAATTGCACTCATTGAGGATTGAAAC	CTTTTGGCTGTTAATGATGCGGTGGGTCTTGCCACAG
CTTTATATCTAATTGCACTCATTGAGGATTGAAAC	CCACCTCTCCCTCGATGCTTACTGCATCACGAGGCGAAT


>NC_010803|4|4|1009935-1011874|CRISPRCasFinder
CTTTATATCTAATTGCACTCATTGAGGATTGAAAC	TTGCAGGTCTTCCGCCTGCGAGCTGAATCATGTCC
CTTTATATCTAATTGCACTCATTGAGGATTGAAAC	GTTCTTCTTCGATGCGCTGGCGTTCTGCCTCTTCA
CTTTATATCTAATTGCACTCATTGAGGATTGAAAC	TCATATTGCACTTTCGGCATTGCCATCCTCCACTTT
CTTTATATCTAATTGCACTCATTGAGGATTGAAAC	AACATCCCTATTGTTTTATCGTACAACTCGTCACTT
CTTTATATCTAATTGCACTCATTGAGGATTGAAAC	TCGGAGACATCCTTGTAAGCCTTCACAACATCATTAAAGT
CTTTATATCTAATTGCACTCATTGAGGATTGAAAC	TTATCTCGCGCCGGACGATGTTGTCACCGCAGTACAC
CTTTATATCTAATTGCACTCATTGAGGATTGAAAC	TAGCCGTCGCCTGCCACTATGCTTTCCATACAGGCACC
CTTTATATCTAATTGCACTCATTGAGGATTGAAAC	TATTGTGCAACCCAGATTTCGACACGGCGATTTCGCTCC
CTTTATATCTAATTGCACTCATTGAGGATTGAAAC	AATCTTCAAACTTAATTATTGTTTCTGTTTTATTATATA
CTTTATATCTAATTGCACTCATTGAGGATTGAAAC	ATGCACGTCTTACTCATACTTCTCCCTCCGTTTTGCTCAATT
CTTTATATCTAATTGCACTCATTGAGGATTGAAAC	CTTCTTCCCGGTCGCAAGGCGTGAGCACCGCCGTCACC
CTTTATATCTAATTGCACTCATTGAGGATTGAAAC	TAATCACACTTCCTGACCGTAGCAGCCAGCGCCCCGTCTG
CTTTATATCTAATTGCACTCATTGAGGATTGAAAC	TTAACTCGATAGCGTATGCAATGGCTACGCAAGGGA
CTTTATATCTAATTGCACTCATTGAGGATTGAAAC	TTCCAAATCTCTCATGTTAGCTATGTCCTTATAATCAA
CTTTATATCTAATTGCACTCATTGAGGATTGAAAC	CTCAACCCCATGTAAAAAAGACATAAGACATCTATTTAAA
CTTTATATCTAATTGCACTCATTGAGGATTGAAAC	GCCACCACTTCAGCCTTATCAGTAATTCCCGTAAGATAAA
CTTTATATCTAATTGCACTCATTGAGGATTGAAAC	TACAGGTGGTACACGCCGTCTTTGCGGAGCACTCCCCCG
CTTTATATCTAATTGCACTCATTGAGGATTGAAAC	AACAAATGGAGCTGGGTCGACAACCCGTAGTGCAGC
CTTTATATCTAATTGCACTCATTGAGGATTGAAAC	TAAGCGAATAAACCGCATATAAACCCGCGACCAGCAGG
CTTTATATCTAATTGCACTCATTGAGGATTGAAAC	TTTGGTTCCGGTCTGGTGGTAGCCCATGTATTTGATTGC
CTTTATATCTAATTGCACTCATTGAGGATTGAAAC	TTGCGTCGAAACCTTGTTTCGAAAGTTTTCTCTGAAA
CTTTATATCTAATTGCACTCATTGAGGATTGAAAC	TTGATTTAAGCACGCCGGCGTTCAGCAATTGCCCCCCG
CTTTATATCTAATTGCACTCATTGAGGATTGAAAC	TTTCCATTTCCGAAAGTATTTCTTCAGCTTTTTCAAGAT
CTTTATATCTAATTGCACTCATTGAGGATTGAAAC	CTTTTGGCTGTTAATGATGCGGTGGGTCTTGCCACAG
CTTTATATCTAATTGCACTCATTGAGGATTGAAAC	CCACCTCTCCCTCGATGCTTACTGCATCACGAGGCGAAT
CTTTATATCTAATTGCACTCATTGAGGATTGAAAC	AACCGTTTGATGCTGCTGCAATCGTCATGCCATCACGGAGAACA
CTTTATATCTAATTGTACTCATTGAGGATATATTT

>NC_010803|4|2|1009935-1011874|CRT
CTTTATATCTAATTGCACTCATTGAGGATTGAAAC	TTGCAGGTCTTCCGCCTGCGAGCTGAATCATGTCC
CTTTATATCTAATTGCACTCATTGAGGATTGAAAC	GTTCTTCTTCGATGCGCTGGCGTTCTGCCTCTTCA
CTTTATATCTAATTGCACTCATTGAGGATTGAAAC	TCATATTGCACTTTCGGCATTGCCATCCTCCACTTT
CTTTATATCTAATTGCACTCATTGAGGATTGAAAC	AACATCCCTATTGTTTTATCGTACAACTCGTCACTT
CTTTATATCTAATTGCACTCATTGAGGATTGAAAC	TCGGAGACATCCTTGTAAGCCTTCACAACATCATTAAAGT
CTTTATATCTAATTGCACTCATTGAGGATTGAAAC	TTATCTCGCGCCGGACGATGTTGTCACCGCAGTACAC
CTTTATATCTAATTGCACTCATTGAGGATTGAAAC	TAGCCGTCGCCTGCCACTATGCTTTCCATACAGGCACC
CTTTATATCTAATTGCACTCATTGAGGATTGAAAC	TATTGTGCAACCCAGATTTCGACACGGCGATTTCGCTCC
CTTTATATCTAATTGCACTCATTGAGGATTGAAAC	AATCTTCAAACTTAATTATTGTTTCTGTTTTATTATATA
CTTTATATCTAATTGCACTCATTGAGGATTGAAAC	ATGCACGTCTTACTCATACTTCTCCCTCCGTTTTGCTCAATT
CTTTATATCTAATTGCACTCATTGAGGATTGAAAC	CTTCTTCCCGGTCGCAAGGCGTGAGCACCGCCGTCACC
CTTTATATCTAATTGCACTCATTGAGGATTGAAAC	TAATCACACTTCCTGACCGTAGCAGCCAGCGCCCCGTCTG
CTTTATATCTAATTGCACTCATTGAGGATTGAAAC	TTAACTCGATAGCGTATGCAATGGCTACGCAAGGGA
CTTTATATCTAATTGCACTCATTGAGGATTGAAAC	TTCCAAATCTCTCATGTTAGCTATGTCCTTATAATCAA
CTTTATATCTAATTGCACTCATTGAGGATTGAAAC	CTCAACCCCATGTAAAAAAGACATAAGACATCTATTTAAA
CTTTATATCTAATTGCACTCATTGAGGATTGAAAC	GCCACCACTTCAGCCTTATCAGTAATTCCCGTAAGATAAA
CTTTATATCTAATTGCACTCATTGAGGATTGAAAC	TACAGGTGGTACACGCCGTCTTTGCGGAGCACTCCCCCG
CTTTATATCTAATTGCACTCATTGAGGATTGAAAC	AACAAATGGAGCTGGGTCGACAACCCGTAGTGCAGC
CTTTATATCTAATTGCACTCATTGAGGATTGAAAC	TAAGCGAATAAACCGCATATAAACCCGCGACCAGCAGG
CTTTATATCTAATTGCACTCATTGAGGATTGAAAC	TTTGGTTCCGGTCTGGTGGTAGCCCATGTATTTGATTGC
CTTTATATCTAATTGCACTCATTGAGGATTGAAAC	TTGCGTCGAAACCTTGTTTCGAAAGTTTTCTCTGAAA
CTTTATATCTAATTGCACTCATTGAGGATTGAAAC	TTGATTTAAGCACGCCGGCGTTCAGCAATTGCCCCCCG
CTTTATATCTAATTGCACTCATTGAGGATTGAAAC	TTTCCATTTCCGAAAGTATTTCTTCAGCTTTTTCAAGAT
CTTTATATCTAATTGCACTCATTGAGGATTGAAAC	CTTTTGGCTGTTAATGATGCGGTGGGTCTTGCCACAG
CTTTATATCTAATTGCACTCATTGAGGATTGAAAC	CCACCTCTCCCTCGATGCTTACTGCATCACGAGGCGAAT
CTTTATATCTAATTGCACTCATTGAGGATTGAAAC	AACCGTTTGATGCTGCTGCAATCGTCATGCCATCACGGAGAACA
CTTTATATCTAATTGTACTCATTGAGGATATATTT

>NC_010803|4|3|1011541-1011795|PILER-CR
	TTGCAGGTCTTCCGCCTGCGAGCTGAATCATGTCC
CTTTATATCTAATTGCACTCATTGAGGATTGAAAC	GTTCTTCTTCGATGCGCTGGCGTTCTGCCTCTTCA
CTTTATATCTAATTGCACTCATTGAGGATTGAAAC	TCATATTGCACTTTCGGCATTGCCATCCTCCACTTT
CTTTATATCTAATTGCACTCATTGAGGATTGAAAC	AACATCCCTATTGTTTTATCGTACAACTCGTCACTT
CTTTATATCTAATTGCACTCATTGAGGATTGAAAC	TCGGAGACATCCTTGTAAGCCTTCACAACATCATTAAAGT
CTTTATATCTAATTGCACTCATTGAGGATTGAAAC	TTATCTCGCGCCGGACGATGTTGTCACCGCAGTACAC
CTTTATATCTAATTGCACTCATTGAGGATTGAAAC	TAGCCGTCGCCTGCCACTATGCTTTCCATACAGGCACC
CTTTATATCTAATTGCACTCATTGAGGATTGAAAC	TATTGTGCAACCCAGATTTCGACACGGCGATTTCGCTCC
CTTTATATCTAATTGCACTCATTGAGGATTGAAAC	AATCTTCAAACTTAATTATTGTTTCTGTTTTATTATATA
CTTTATATCTAATTGCACTCATTGAGGATTGAAAC	ATGCACGTCTTACTCATACTTCTCCCTCCGTTTTGCTCAATT
CTTTATATCTAATTGCACTCATTGAGGATTGAAAC	CTTCTTCCCGGTCGCAAGGCGTGAGCACCGCCGTCACC
CTTTATATCTAATTGCACTCATTGAGGATTGAAAC	TAATCACACTTCCTGACCGTAGCAGCCAGCGCCCCGTCTG
CTTTATATCTAATTGCACTCATTGAGGATTGAAAC	TTAACTCGATAGCGTATGCAATGGCTACGCAAGGGA
CTTTATATCTAATTGCACTCATTGAGGATTGAAAC	TTCCAAATCTCTCATGTTAGCTATGTCCTTATAATCAA
CTTTATATCTAATTGCACTCATTGAGGATTGAAAC	CTCAACCCCATGTAAAAAAGACATAAGACATCTATTTAAA
CTTTATATCTAATTGCACTCATTGAGGATTGAAAC	GCCACCACTTCAGCCTTATCAGTAATTCCCGTAAGATAAA
CTTTATATCTAATTGCACTCATTGAGGATTGAAAC	TACAGGTGGTACACGCCGTCTTTGCGGAGCACTCCCCCG
CTTTATATCTAATTGCACTCATTGAGGATTGAAAC	AACAAATGGAGCTGGGTCGACAACCCGTAGTGCAGC
CTTTATATCTAATTGCACTCATTGAGGATTGAAAC	TAAGCGAATAAACCGCATATAAACCCGCGACCAGCAGG
CTTTATATCTAATTGCACTCATTGAGGATTGAAAC	TTTGGTTCCGGTCTGGTGGTAGCCCATGTATTTGATTGC
CTTTATATCTAATTGCACTCATTGAGGATTGAAAC	TTGCGTCGAAACCTTGTTTCGAAAGTTTTCTCTGAAA
CTTTATATCTAATTGCACTCATTGAGGATTGAAACTTGATTTAAGCACGCCGGCGTTCAGCAATTGCCCCCCGCTTTATATCTAATTGCACTCATTGAGGATTGAAAC	TTTCCATTTCCGAAAGTATTTCTTCAGCTTTTTCAAGAT
CTTTATATCTAATTGCACTCATTGAGGATTGAAAC	CTTTTGGCTGTTAATGATGCGGTGGGTCTTGCCACAG
CTTTATATCTAATTGCACTCATTGAGGATTGAAAC	CCACCTCTCCCTCGATGCTTACTGCATCACGAGGCGAAT
CTTTATATCTAATTGCACTCATTGAGGATTGAAAC

Protein	Signature genes	Signature genes Name	Protein_function
NC_010803.1\|WP_012465873.1\|997964_999020_-\|arsenosugar-biosynthesis-radical-SAM-protein-ArsS	unknown	unknown	gnl\|CDD\|275025
NC_010803.1\|WP_150081559.1\|1027956_1029167_+\|IS3-family-transposase	unknown	unknown	gnl\|CDD\|222853
NC_010803.1\|WP_012465889.1\|1018683_1019955_+\|hypothetical-protein	cmr6gr7	mkCas0142_cmr6gr7_CAS-III-C	gnl\|CDD\|187857
NC_010803.1\|WP_041465884.1\|996660_997350_-\|TIGR04283-family-arsenosugar-biosynthesis-glycosyltransferase	unknown	unknown	gnl\|CDD\|275103
NC_010803.1\|WP_041465887.1\|1006596_1007577_+\|transposase	unknown	unknown	gnl\|CDD\|376616
NC_010803.1\|WP_012465881.1\|1005837_1006113_-\|DUF2442-domain-containing-protein	unknown	unknown	gnl\|CDD\|378424
NC_010803.1\|WP_012465894.1\|1024985_1026407_+\|hypothetical-protein	unknown	unknown	unknown
NC_010803.1\|WP_012465882.1\|1006123_1006384_-\|DUF4160-domain-containing-protein	unknown	unknown	gnl\|CDD\|379344
NC_010803.1\|WP_012465890.1\|1019951_1022768_+\|CRISPR-associated-protein-Csx11	cas10	cd09701_cas10_CAS-III-C	gnl\|CDD\|187832
NC_010803.1\|WP_012465874.1\|999391_1000753_-\|FAD-dependent-oxidoreductase	unknown	unknown	gnl\|CDD\|131778
NC_010803.1\|WP_012465876.1\|1001335_1001863_+\|Lrp/AsnC-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|224439
NC_010803.1\|WP_012465892.1\|1023749_1024124_+\|hypothetical-protein	cmr5gr11	mkCas0060_cmr5gr11_CAS-III-C	unknown
NC_010803.1\|WP_012465878.1\|1004134_1004554_-\|YjbQ-family-protein	unknown	unknown	gnl\|CDD\|223509
NC_010803.1\|WP_150081556.1\|1001924_1004069_+\|glutamine-synthetase-III	unknown	unknown	gnl\|CDD\|226477
NC_010803.1\|WP_012465893.1\|1024123_1024927_+\|hypothetical-protein	cmr3gr5	mkCas0067_cmr3gr5_CAS-III-C	unknown
NC_010803.1\|WP_012465891.1\|1022760_1023753_+\|hypothetical-protein	cmr4gr7	COG1336_cmr4gr7_CAS-III-C	gnl\|CDD\|224255
NC_010803.1\|WP_012465887.1\|1012745_1014941_+\|CRISPR-associated-endonuclease-Cas1	cas1	cd09634_cas1_CAS-I:CAS-II:CAS-III:CAS-V	gnl\|CDD\|376633
NC_010803.1\|WP_012465886.1\|1012341_1012626_+\|CRISPR-associated-endonuclease-Cas2	cas2	pfam09827_cas2_CAS-I:CAS-II:CAS-III	gnl\|CDD\|187856
NC_010803.1\|WP_012465888.1\|1017691_1018687_+\|type-III-B-CRISPR-module-RAMP-protein-Cmr1	cmr1gr7	cd09657_cmr1gr7_CAS-III-C	gnl\|CDD\|273859
NC_010803.1\|WP_041465671.1\|1007634_1008807_-\|ATP-binding-protein	unknown	unknown	gnl\|CDD\|224292

Protein	Function_ID	Function_description	E-value
NC_010803.1\|WP_012465873.1\|997964_999020_-\|arsenosugar-biosynthesis-radical-SAM-protein-ArsS	gnl\|CDD\|275025	TIGR04167, radical_SAM_domain_protein, radical SAM/Cys-rich domain protein. Members of this protein family have an N-terminal radical SAM domain (pfam04055) and a C-terminal pfam12345 domain. The C-terminal region has several conserved Cys residues, one of which is replaced by selenocysteine in at least five bacterial reference genomes.	0
NC_010803.1\|WP_150081559.1\|1027956_1029167_+\|IS3-family-transposase	gnl\|CDD\|222853	PHA02517, PHA02517, putative transposase OrfB; Reviewed.	7.70772e-45
NC_010803.1\|WP_012465889.1\|1018683_1019955_+\|hypothetical-protein	gnl\|CDD\|187857	cd09726, RAMP_I_III, CRISPR/Cas system-associated RAMP superfamily protein. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; RAMP superfamily proteins.	5.45249e-10
NC_010803.1\|WP_041465884.1\|996660_997350_-\|TIGR04283-family-arsenosugar-biosynthesis-glycosyltransferase	gnl\|CDD\|275103	TIGR04283, glycosyl_transferase_family_2, transferase 2, rSAM/selenodomain-associated. This enzyme may transfer a nucleotide, or it sugar moiety, as part of a biosynthetic pathway. Other proposed members of the pathway include another transferase (TIGR04282), a phosphoesterase, and a radical SAM enzyme (TIGR04167) whose C-terminal domain (pfam12345) frequently contains a selenocysteine. [Unknown function, Enzymes of unknown specificity].	2.70972e-97
NC_010803.1\|WP_041465887.1\|1006596_1007577_+\|transposase	gnl\|CDD\|376616	pfam01797, Y1_Tnp, Transposase IS200 like. Transposases are needed for efficient transposition of the insertion sequence or transposon DNA. This family includes transposases for IS200 from E. coli.	3.02347e-06
NC_010803.1\|WP_012465881.1\|1005837_1006113_-\|DUF2442-domain-containing-protein	gnl\|CDD\|378424	pfam10387, DUF2442, Protein of unknown function (DUF2442). This family of bacterial and fungal proteins has several members annotated as being putative molybdopterin-guanine dinucleotide biosynthesis protein A; however this could not be verified. Hence the function is not known. This family also includes the DUF3532 that was found to be related and was merged into this family. Members of this family also fall into the NE0471 N-terminal domain-like superfamily, a family of proteins with a unique fold in SCOP:143880.	8.02539e-14
NC_010803.1\|WP_012465882.1\|1006123_1006384_-\|DUF4160-domain-containing-protein	gnl\|CDD\|379344	pfam13711, DUF4160, Domain of unknown function (DUF4160).	2.24855e-18
NC_010803.1\|WP_012465890.1\|1019951_1022768_+\|CRISPR-associated-protein-Csx11	gnl\|CDD\|187832	cd09701, Cas10_III, CRISPR/Cas system-associated protein Cas10. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Multidomain protein with permuted HD nuclease domain, inactivated palm domain and Zn-ribbon; signature gene for type III.	0
NC_010803.1\|WP_012465874.1\|999391_1000753_-\|FAD-dependent-oxidoreductase	gnl\|CDD\|131778	TIGR02731, Phytoene_dehydrogenase_chloroplastic/chromoplastic, phytoene desaturase. Plants and cyanobacteria (and, supposedly, Chlorobium tepidum) have a conserved pathway from two molecules geranylgeranyl-PP to one of all-trans-lycopene. Members of this family are the enzyme pytoene desaturase (also called phytoene dehydrogenase). This model does not include the region of the chloroplast transit peptide in plants. A closely related family, excluded by this model, is zeta-carotene desaturase, another enzyme in the same pathway. [Biosynthesis of cofactors, prosthetic groups, and carriers, Other].	3.59526e-131
NC_010803.1\|WP_012465876.1\|1001335_1001863_+\|Lrp/AsnC-family-transcriptional-regulator	gnl\|CDD\|224439	COG1522, Lrp, Transcriptional regulators [Transcription].	5.28431e-34
NC_010803.1\|WP_012465878.1\|1004134_1004554_-\|YjbQ-family-protein	gnl\|CDD\|223509	COG0432, COG0432, Uncharacterized conserved protein [Function unknown].	1.5103e-52
NC_010803.1\|WP_150081556.1\|1001924_1004069_+\|glutamine-synthetase-III	gnl\|CDD\|226477	COG3968, COG3968, Uncharacterized protein related to glutamine synthetase [General function prediction only].	0
NC_010803.1\|WP_012465891.1\|1022760_1023753_+\|hypothetical-protein	gnl\|CDD\|224255	COG1336, COG1336, CRISPR system related protein, RAMP superfamily [Defense mechanisms].	8.81904e-44
NC_010803.1\|WP_012465887.1\|1012745_1014941_+\|CRISPR-associated-endonuclease-Cas1	gnl\|CDD\|376633	pfam01867, Cas_Cas1, CRISPR associated protein Cas1. Clustered regularly interspaced short palindromic repeats (CRISPRs) are a family of DNA direct repeats found in many prokaryotic genomes. This family of proteins corresponds to Cas1, a CRISPR-associated protein. Cas1 may be involved in linking DNA segments to CRISPR.	1.49377e-104
NC_010803.1\|WP_012465886.1\|1012341_1012626_+\|CRISPR-associated-endonuclease-Cas2	gnl\|CDD\|187856	cd09725, Cas2_I_II_III, CRISPR/Cas system-associated protein Cas2. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas2 is present in majority of CRISPR/Cas systems along with Cas1; RNAse specific to U-rich regions; Possesses an RRM/ferredoxin fold.	7.02181e-28
NC_010803.1\|WP_012465888.1\|1017691_1018687_+\|type-III-B-CRISPR-module-RAMP-protein-Cmr1	gnl\|CDD\|273859	TIGR01894, hypothetical_protein, CRISPR type III-B/RAMP module RAMP protein Cmr1. CRISPR is a term for Clustered, Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins. This model represents the region of stongest conservation, the N-terminal half, of one such family, represented by TM1795 from Thermotoga maritima. This protein is the first of a set of six genes, mostly from the RAMP superfamily, that we designated the CRISPR-associated RAMP module.	9.41908e-19
NC_010803.1\|WP_041465671.1\|1007634_1008807_-\|ATP-binding-protein	gnl\|CDD\|224292	COG1373, COG1373, Predicted ATPase (AAA+ superfamily) [General function prediction only].	2.1081e-62

>NC_010803.1|WP_041465671.1|1007634_1008807_-|ATP-binding-protein
MIHRTLTRNLQDALEVYPAVALLGPRQSGKTTLALEVGKSFDALYLDLESEQDRARLANPELYLSDHLERLVILDEVHRTPGLFPVLRGLIDRSRRAGRRSGLYLLLGSASLDLLKQTGESLAGRISYIELTPFTILEAGTGNVDKLWTRGGFPDSMLASTEPISFRWRQDFIRTYLERDIPQFGPRIAAETLRRFWTMLAWHQGGMVNMSQFSRSLGIDVKTVSNYMDLLVDLLLVRRLPPWHENPGKRLVRTPKVFIRDSGLTHALLGIADKDMLLSHPVVGQSWECFVIENILDSAPADVQGYFYRTGGGAEIDLLLVWPDGKRWAVEVKRSLTPKLERGFHSAHADLGPERSFVVYPGTERYRISETVEAISLADLALELQLANKR
>NC_010803.1|WP_041465887.1|1006596_1007577_+|transposase
MPRGARLDAPGTLHHVMVRGTEGMAIVQDDEDREGFVGRLGMVVAATGTSMYAWALMSNHAHMLLRSGPSGLSTFMRKFLTGYASFYNRRHKRHGHLFQNRYKSIVCEEEPYFLRLVSYIHLNPLRAGLVRSMEELDGYRWSGHAVVLNRIRHDWQNREAVLGYFGKRESSAMQAYREFVATESGLGRQPELTGGGLIRSIGGWSEVKSLRKRSEKQFSDERILGSGEFVKEILKEAEDGVKERLPAVSLECEAQERLQRLCEEKGVAVKVMHAGSRTRQCSAIRRQLAEEFVEELGMSYAGAARILGISASGVNQILMRDRKKLQ
>NC_010803.1|WP_012465882.1|1006123_1006384_-|DUF4160-domain-containing-protein
MPEISRFFGIIIRMFYDEHNPPHFHAEFQGKSSVFDFQGNILKGSLGSRTAVKLVREWIDLHTDDLLADWELASSNKEIKPIEPLN
>NC_010803.1|WP_012465881.1|1005837_1006113_-|DUF2442-domain-containing-protein
MWNMNDVIGITYVGGYTYHVTFDDGLRGDIDFSEYPEKGPVFAPLKELGFFRKAFIEGGTIAWPNGADIAPESLYEKLLQKEQNRECVVRQ
>NC_010803.1|WP_012465878.1|1004134_1004554_-|YjbQ-family-protein
MKSYHKELWMQVPARMDFVNITGDVEKALLESGIQEGLCLVNAMHITASVFINDNEPGLHQDYKRWLEELAPHEPISRYRHNMTGEDNGDAHHKRQIMGREVVVAVTKGKLHFGAWEQIFYGEFDGMRKKRVLVKIIGE
>NC_010803.1|WP_150081556.1|1001924_1004069_+|glutamine-synthetase-III
MNMESKVPVSSYFGAMTFDQKAMRARLPKDEFKALQDTIRAGKKITGEIAGVVAHGMKEWAMEQGATHYTHWFQPMTGSTAEKHDAFLSIDRDGTPIERFSGEQLIQGEPDASSFPSGGMRTTFEARGYTAWDPSSPAFLMKGGTGLTLCIPTVFISYHGEALDSKTPLLRSMDAVSNSAIRLLNVLGTTGISRVKTFAGCEQEYFLIDKKFYSERPDLIMCGRTLLGALPPKGQQLEDHYFGSIPDRVLEFMQDVEHELYLLGIPAKTRHNEVAPHQFEIAPIFEEANIAVDHNLLVMEVMRKVADKKGFALLLTEKPFAGINGSGKHNNWSIGTDTGINLLDPGDTPTENINFLVFLVAVLKGVYKRADVLRMSIASTGNDHRLGANEAPPAVVTVFLGEQLETVLDAIESGKVDLKTEKQVLNLGLSQVPLLNKDYTDRNRTSPFAFTGNKFEFRAVGSSQAASVPNMVLNTLMAEALDELTDAIEAKIAAGKDRDSAVLEAIREGITATKDIRYPGDNYSEALQQAAKERGLPNLKNTPQALRTLEKSDVKAMFVKYGVLTEQEIESRLNIRLERYVKGIDIEARTLQLMLKTLVIPDVSEYQGDIGNSFNNLLAASEAIGLSEGAIASQANHFKNLAENLSSLIDLTAELDEAVEKIETIEGEFGKADFCADELLPLMNAVRAVADRLELMVDRSRWQLPTYSEMLFEH
>NC_010803.1|WP_012465876.1|1001335_1001863_+|Lrp/AsnC-family-transcriptional-regulator
MSGHLDLIDLKIIESLGENGRLRLSELAEVVALSIPSVSERLDKLQKNGIIRSFTMEVDERQLGFDIQAFVRVRIDSSKHYKSFMEHVLQEDEIMECFSVTGEGSHILKVMTHNTSSLEKFLSRIQSWPGVLETNTSFVLSQLKRTRKISAEIVRNNLQDRQVLITFDEKKSRKV
>NC_010803.1|WP_012465874.1|999391_1000753_-|FAD-dependent-oxidoreductase
MKIAIFGAGVAGLSAAIELVDRGHAVELYEKRKVLGGKVSVWKDNDGDSIESGLHIVFGGYEQLQQYMKKVGAAENYLWKEHSLIYAEPDGKQSFFKKANLPSPWAEVVGGMQADFLTMWDKISLIKGLYPALAGNEEYFRSQDHMTYSEWHRLRGASEHSLEKLWRAIALAMNFIEPNVISARPMITIFKYFGTDYAATKFAFFRKNPGDSMIEPMRQYIQTRGGRIFVDAKLNRFELNSDETVKCAVLQDGQKIEADAYISALPVHNIKNIVPGEWFNHAYFRNLHQFVGSPVANCQLWFDRKITATDNLMFSQGTTFATFADVSITCPDDFQKGMGSAEGGSVMSLVLAPAHQLMDLPNDVITRLVMKDIHDRFPLSRDAKLLKSTIVKIPQSVYKAVPDVDKFRPDQASPVKNFFLAGDYTYQRYLASMEGAALSGRQAAEKLHTRLGG
>NC_010803.1|WP_012465873.1|997964_999020_-|arsenosugar-biosynthesis-radical-SAM-protein-ArsS
MTIHPSLHKRKNPLAESGEQIRVLEKTDCSIPPFGSKLAETGNGPLRPDGTAILQVNIGYRCNLLCRHCHVDGGPDRSETMSRETMQHCLDALSKSRIQTLDITGGAPEMNPDLPWFIREARKIMPEGEILVRTNLVILVSGEEYRHFPELFRENRVSLIASLPCYTRENVDAQRGKGVFDRSIEALRMLNATGYGKDGSPLQLNLVFNPGGPSLPGAQQALEADYKSRLRQEFGIEFSHLYTITNMPVSRFLESLLEEGGFCRYMNLLESHFNPEAVKNLMCRNTVSVGWDGALYDCDFNQMLKLPMREPAPRTISDFDEALLHDRTIAIGQHCYGCTAGAGSSCQGCLL
>NC_010803.1|WP_041465884.1|996660_997350_-|TIGR04283-family-arsenosugar-biosynthesis-glycosyltransferase
MGSLSIIIPTFNEETGIARTLDTLLALTGRYDDVEIIVSDSGTDRTAEIVSAFPVTLCRSEKGRARQMNAGAKLARHHTLYFLHADTLPPERFVDDIVDAVGSGKEAGCFRMQFDDPHPIMTLFGWFTRVPLSICRGGDQSLFITKELFDALGGFDERMQVMEDIDIIERIERRGTFHILDNHVVTSARKYHKNGILRLQAIFGTIHLMYALGYDQESIIRYYQENIES
>NC_010803.1|WP_012465886.1|1012341_1012626_+|CRISPR-associated-endonuclease-Cas2
MQFILVTYDIENDRRRTKIHKVLEGYGISVQYSVFECFLSDNDYAGLRQRLQNLLDPNHPLDSIRYYRLCRNCVEIVDVDGNRPFEIDSPFVIS
>NC_010803.1|WP_012465887.1|1012745_1014941_+|CRISPR-associated-endonuclease-Cas1
MGWLYNQMAMPETIFQAWYKVASNDGRPGWDNKSIEDYSLQLEENLKALSQALLTGTYKQGPLMKLVLLKPDGKDRVLLIPGVMDRVAQTAAAIVLSPIIEAELGNCTFAYRPGISREGAAREIDRLHREGYQWVLDADIRSFFDNVRHDLLFQRLVELIDDKEMISLLHRWLTAEIVDGINPRIQNTMGLPQGCPISPALANLYLDRFDETMEKEGFKLVRFADDYLVLCKTRPKAEAALKLSETALAELKLELHSDKTRITTFAEGFKYLGYLFIRALVIPTKMHPEEWYDKLGKFKLRKKSEHALPSDPDAMTGETAKFELETDQGEKIELTKNELLQTEFGCKLLESLDKKQLSVDEFLEKVARQDEERQKEKRDALKKLYSPFLNTLYLQEQGSLMRKDGERFSIEKDGAVINEVIVRRIEQVVVFGNIALTTPVMQYCMQNEIPVTFLSQHGKYFGRLESTMADNAEMQRYHFLRSIDEPFALETARSIVSAKIGNSRTMIRRRKSVMQDCDGTLQSKMTCNLDIMADLLLKAETSTDIDVLRGLEGKASALYFECYGMFFSKNLPFHTASFLRVRRPPTDPVNSLLSFGYSLLHTNVFSMVQMSGLNPYIGFLHAERKGNPALVNDLVEEFRTVIDSLVLYTINRGLLHENDFYYRKDQPGCFLSNDARKRFLQIFETRMWQESRDGYTGKTLNFRRHIEKQVRIMRDVISGTRTQYDPYKLVW
>NC_010803.1|WP_012465888.1|1017691_1018687_+|type-III-B-CRISPR-module-RAMP-protein-Cmr1
MKANIELRTLTPIWTGGVETGKMERIHETGIIGNLRWWYEAIVRGLGGEACDPTTHSCAYDREKPNNGLCDVCQVFGATGWRRRFNLSVHETQMQPQSVTHPMRANRIYQNRQGKNIPPTWYFPNPPQGGNFLIEVQSSSSVFSVELVQGLIQLSVDWTALGARTQMGFGVTSLVRGRLNANPFNYLRLTCCGSSNNLPSLQNMFFAQIEKENITDQETFNIKYDLRRLFAGNQDVRHFVMGTVQEERIAAKIHVSRPYANGLIRVWGWVPVDANVWNDKWNRDGVLTQIKNHLESNYALKTWREFNNDRDINQQYSDVRAYLHSLWESKK
>NC_010803.1|WP_012465889.1|1018683_1019955_+|hypothetical-protein
MNQTFKSFVEPFPHTISEISELLSNLSQAEQAIKVNKRNKEVRQQYENQAKDLHRQLLTHKDCSLIYNYMEATGIADKDTFRSTWAREKLKVDSDELPDFLKPPLLDDLSCLPVGSFYIQFKFTLLKPYISRDDNAFYLVDNSIVREKVFRFPMVRSTAWKGSLRHALWQMDGYQKEDQQDQQIKRLFGTANDEQPEEGNSGRFYFYPSFFTLNSLEVINPHGRKTRVGTTPILFESVPIGAEATFTLLYSPLDRIGREDVETRQQVIADLKLVAEGLRALFIVYGFGAKTSSGFGLANDAIENGSLILNLPSFVFPQAETVQVQTPEDVFLKYMDESGYLKTVFSGGGDYGLMSNKEYGEKREQLGGGYLTEFKAFRKWYGENGEQWQKSIKEKSSATNYPQLRFKSLSQLAERMRQTGGEA
>NC_010803.1|WP_012465890.1|1019951_1022768_+|CRISPR-associated-protein-Csx11
MSQLDQLIQHRDAILLAEAIGWLHDYWKCSEEQLQKQSPINDKDLKLKPKEIALQEITKRFSSLGNTLLEISTAKESLSDLLNQWHGKAGNAGASFLLQYLSRCHNTAHFDKQDPLKSGRQNYPDTQISSAFGFETAVGSCLSAQLWALPWDSLITNHDHERSTLRQAVQSLFSNVGADTRRPINEISLWDWGLLVGALYKTALAAVALGQSPVTHDLRWRLLGIRTDALAYFSNVSRLPDLVARQNTLQTAINNVQTLLETVYPVATEVYRDENGSLYVVPDMANLLGLQDSSDKTLLSLIKEQFACDGEIVPDITLDPNPWWGQDPVRAGNDEIPPAGSILSSPVTWKSDADAVREAWKEQRQTVCPICGLRSCVNRQLDYCQICGDRRKGRVKEWLQEQNKTIWIDEVADRNGRLALITGTFNLTNWLDGSLVETMLVKEPTDSNPSVPKIPSFARLRRIWQTTRTFWKQSQSDIDQHLTDARRRLTIRLANSPKLTPNQTYELDLGGQTRMSVLWDGNHLLSIDNLSYTASQLGFPLNNFETKENWTPEDLALDVCAWVKQHKESWSGQKQVFQLFSDEEKNKQFDIQIGDMGYQDAAYASTIPILAEPRTFMVLVPADCALDLIHAIKTKYEREIGKVRNRLSLHLGAVYFHRRTPLRAALDAGRRMLKYDLGQMKDEVWIVKEDAKRELLPLEKQYLAEEENKQLAEAVAVKLEQNGRFLTWYVPARMGDGKTDDSWYPYVFIQNDVSKRKHIFKALRPKSDHTTEECWLIHATKLQAGDRVYFTPATFDFQWLGSSGERFEIAYENGKRRNQPMRPYLLDELTTIQQAWKVIAGKGGLTANQIYALRDLIEIKRENWQPSANHWVQDCYSQTGMFWLFCRDVINNANWKNKPVDEEINLLINWAVSGLLADVIHLHMGVMKQKPQREENNE
>NC_010803.1|WP_012465891.1|1022760_1023753_+|hypothetical-protein
MSNQNSNHCHKQRFLLQTLDPVHVGTGGNRLGRVDLSIVREPGTRLPKIPGTSLHGAIRQYAAVCYESLRCAGAGQGNESKGKEPHCRDAQCPVCYTFGYMNGQDGGQSGQISISDARLLLFPVYSLAGPVWVTSPSILSEFGVPTNDPCDQVCLPDVLTSQEHLNLGWLMLAKASDPFNWPDAIKGVPVEITSRAVLVSDKLFSQIVNSNLEVRTSVSIDPETGAAVDKALFTYEAIPRATILWMDVIEDDFRGVFPGTDKKCRTTIDEKEGTKKKTYEHNAGDPLIEPWNRPLDVVKSALKLAEMLGIGGMGTRGFGRVRLLNEGSES
>NC_010803.1|WP_012465892.1|1023749_1024124_+|hypothetical-protein
MTQLNLDQLAARYAQKIVEKGKADIENPVTKALGVLQEQGVYACILYLLANKHDNILKPLYQLVGELPGFRGNEKMPDEKIDSKEMLKFYGDCVCSDLDTLLLVKELYEQTLIYARYGAKAAGK
>NC_010803.1|WP_012465893.1|1024123_1024927_+|hypothetical-protein
MTWQKYELVFRMLAPLHIGYRTAGNLMQTRSYVPGRVLWAALTTRLTRDEENGTDGLRYIEIGQQVQDHFRFTYLYPATQNGNGYKTYYPWEKDFDYLFLNSYASTSLNYASQSAEEAMLHETEFIAPHTRTGQSVYLVGNVYTKTNLPTPLENWPKALEKLQLGAERGYGWGRVRTVSCDSQGERFYNEPVAELFDGHITAHLKAEKVSGIVGPVEPLIGWERNNDINRKSNWRLTEEAIICYVPGAKVTVDGNYIIGPNGVCGIN
>NC_010803.1|WP_012465894.1|1024985_1026407_+|hypothetical-protein
MVALHDHFVKLVIPFEYSKEYTDAITAINAAVCWEPNTRVPRDMFLHIKHLISSETSNNSIGVSYVLTAAGRLTCNFPLLKDQAGVLLKKGSGDPELPDFEIKFTVPEVYLFLFETQVGFIILDIKYIESGSLEVVEMANHQLKKIGLSRSFICRDGEKPEKAKKGIGFFDRFFESLKPLVSLVSFFEEQERMLRHLYLFNYLILDHLPESDTEKNNFIVETLFRLRNGFHAHYRPSKKEYDPESNSQVLSFVYNIFWGVSQEGVACVACLTGDSRQTHFLTHIFNYNVENSYFYLYILAMAQRFSLLIIAKKTADIPPEIRGSIEELKNKKEIICAIDALRQDIVLYGLRINYSQVSYNFHYTLFYEKLREVFRLDYQHTELDTEVKNLGALIDIIEQKKRINFELNAAVALLVFAVVSVLSDGLSFFQFMNLFDTHRPLLSLTGLILVVVIVLMLFRYFLKKDVLFNIRKR
>NC_010803.1|WP_150081559.1|1027956_1029167_+|IS3-family-transposase
MSEKQRKSFTAQFKAKVALEAIRGEKTLNEIGREFGIHPNLVGQWKREVQEHAAGLFEAKRGPKPVDPLADPEKLYAEIGRLKVELNWLKKKGRSVPMKARKNWISDKEQLSVSTQCELAGVTRSGYYGQSKSLMPNTEDLELMKLIDEEYTRHPFYGSRRMKQVLLTQGRKVNRKRVQRLMRNLGLAGMAPGPNTSKPHPQHKIYPYLLRGLSITRPNHVWSTDVTYCRLPGGFMYLTAVIDWYSRKVLAWRLSNSLDSSYCVDCLEEAIRKYGTPEIFNTDQGVQYTSDAFTSVLKSHEIRISMDGRGRALDNVFVERLWRNVKQEDLYLKGYETAVEMMRGFAEYFRFYNIERPHQSLGYKTPDEVYESAIGGGARIVDKFSKSVSEGSSEATGPQQEAA

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Crispr_ID: NC_010803_5

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_010803_5

1015192-1016258

TypeIII

Consensus_repeat	Method
CTTTATATCTAATTGCACTCA	PILER-CR
CTTTATATCTAATTGCACTCATTGAGGATTGAAAC	CRISPRCasFinder
CTTTATATCTAATTGCACTCANTGAGGATTGAAAC	CRT

14 spacers

cas1,cas2,cmr1gr7,cmr6gr7,cas10,cmr4gr7,cmr5gr11,cmr3gr5,cas6

The CRISPR arrays of NC_010803_5

>merge|NC_010803|5|1015192-1016258|PILER-CR,CRISPRCasFinder,CRT
CTTTATATCTAATTGCACTCATTGAGGATTGAAACCTGCCCTGTATTGTCTCTTCGTCCGGATCGTTGCCGGGTTCTTTATATCTAATTGCACTCATTGAGGATTGAAACTGTCGATGACGCTATCCATCCTGCCGTTCCATTACTGCTTTATATCTAATTGCACTCATTGAGGATTGAAACTCTAACTATAACGAAGCCGGTCGCCAACGTTACACCGCTTTATATCTAATTGCACTCATTGAGGATTGAAACTTAATAGCCCTTTTTCTTCCTTCTTTTTTAATAAAACTTTATATCTAATTGCACTCATTGAGGATTGAAACTAAAGTTAGGTTTTGATTGTTTACATATACCATGATACTTTATATCTAATTGCACTCATTGAGGATTGAAACAAAGCCGCAACAGGATTTGCTGACATCAACATAGCTGCTGCTTTATATCTAATTGCACTCACTGAGGATTGAAACTCCTTCGAGAAGCGCTCCGGTTTGCTTGAAAATATCCAGCGCCTTTATATCTAATTGCACTCACTGAGGATTGAAACTGTGTTTAGTGATTTTTGAAGATGGAAATTGTAAAAAACTCTTTATATCTAATTGCACTCACTGAGGATTGAAACATCCCGCACCGCCGACCTGCGGTTAAACTCCTCATCACTTTATATCTAATTGCACTCACTGAGGATTGAAACCTTTCCCGTAGTAGAGAGCGCGATGCTGATATGCCGAATGCACAGAGACTTTATATCTAATTGCACTCACTGAGGATTGAAACTCAACGAATCTGTCCCTTTCCTGCTGCACCTGCCGACTTTATATCTAATTGCACTCACCGAGGATTGAAACGCAGTGGACTTTATGGTGTATTCCATCCAGCCGAACTTTATATCTAATTGCACTCACCGAGGATTGAAACGTCCGTGCTCCAGCCTCCGGCAGCCTGATTTTTCCAGTCCTTTATATCTAATTGCACTCACCGAGGATTGAAACGAACAAATGAACCGCGTTCCAACACCCCAAGGAACACCTTTATATCTAATTGCACTGACCGAGGATGAGTTTC

>NC_010803|5|4|1015192-1016171|PILER-CR
CTTTATATCTAATTGCACTCA	TTGAGGATTGAAACCTGCCCTGTATTGTCTCTTCGTCCGGATCGTTGCCGGGTT
CTTTATATCTAATTGCACTCA	TTGAGGATTGAAACTGTCGATGACGCTATCCATCCTGCCGTTCCATTACTG
CTTTATATCTAATTGCACTCA	TTGAGGATTGAAACTCTAACTATAACGAAGCCGGTCGCCAACGTTACACCG
CTTTATATCTAATTGCACTCA	TTGAGGATTGAAACTTAATAGCCCTTTTTCTTCCTTCTTTTTTAATAAAA
CTTTATATCTAATTGCACTCA	TTGAGGATTGAAACTAAAGTTAGGTTTTGATTGTTTACATATACCATGATA
CTTTATATCTAATTGCACTCA	TTGAGGATTGAAACAAAGCCGCAACAGGATTTGCTGACATCAACATAGCTGCTG
CTTTATATCTAATTGCACTCA	CTGAGGATTGAAACTCCTTCGAGAAGCGCTCCGGTTTGCTTGAAAATATCCAGCGC
CTTTATATCTAATTGCACTCA	CTGAGGATTGAAACTGTGTTTAGTGATTTTTGAAGATGGAAATTGTAAAAAACT
CTTTATATCTAATTGCACTCA	CTGAGGATTGAAACATCCCGCACCGCCGACCTGCGGTTAAACTCCTCATCA
CTTTATATCTAATTGCACTCA	CTGAGGATTGAAACCTTTCCCGTAGTAGAGAGCGCGATGCTGATATGCCGAATGCACAGAGA
CTTTATATCTAATTGCACTCA	CTGAGGATTGAAACTCAACGAATCTGTCCCTTTCCTGCTGCACCTGCCGA
CTTTATATCTAATTGCACTCA	CCGAGGATTGAAACGCAGTGGACTTTATGGTGTATTCCATCCAGCCGAA
CTTTATATCTAATTGCACTCA	CCGAGGATTGAAACGTCCGTGCTCCAGCCTCCGGCAGCCTGATTTTTCCAGTC
CTTTATATCTAATTGCACTCA

>NC_010803|5|5|1015192-1016258|CRISPRCasFinder
CTTTATATCTAATTGCACTCATTGAGGATTGAAAC	CTGCCCTGTATTGTCTCTTCGTCCGGATCGTTGCCGGGTT
CTTTATATCTAATTGCACTCATTGAGGATTGAAAC	TGTCGATGACGCTATCCATCCTGCCGTTCCATTACTG
CTTTATATCTAATTGCACTCATTGAGGATTGAAAC	TCTAACTATAACGAAGCCGGTCGCCAACGTTACACCG
CTTTATATCTAATTGCACTCATTGAGGATTGAAAC	TTAATAGCCCTTTTTCTTCCTTCTTTTTTAATAAAA
CTTTATATCTAATTGCACTCATTGAGGATTGAAAC	TAAAGTTAGGTTTTGATTGTTTACATATACCATGATA
CTTTATATCTAATTGCACTCATTGAGGATTGAAAC	AAAGCCGCAACAGGATTTGCTGACATCAACATAGCTGCTG
CTTTATATCTAATTGCACTCACTGAGGATTGAAAC	TCCTTCGAGAAGCGCTCCGGTTTGCTTGAAAATATCCAGCGC
CTTTATATCTAATTGCACTCACTGAGGATTGAAAC	TGTGTTTAGTGATTTTTGAAGATGGAAATTGTAAAAAACT
CTTTATATCTAATTGCACTCACTGAGGATTGAAAC	ATCCCGCACCGCCGACCTGCGGTTAAACTCCTCATCA
CTTTATATCTAATTGCACTCACTGAGGATTGAAAC	CTTTCCCGTAGTAGAGAGCGCGATGCTGATATGCCGAATGCACAGAGA
CTTTATATCTAATTGCACTCACTGAGGATTGAAAC	TCAACGAATCTGTCCCTTTCCTGCTGCACCTGCCGA
CTTTATATCTAATTGCACTCACCGAGGATTGAAAC	GCAGTGGACTTTATGGTGTATTCCATCCAGCCGAA
CTTTATATCTAATTGCACTCACCGAGGATTGAAAC	GTCCGTGCTCCAGCCTCCGGCAGCCTGATTTTTCCAGTC
CTTTATATCTAATTGCACTCACCGAGGATTGAAAC	GAACAAATGAACCGCGTTCCAACACCCCAAGGAACAC
CTTTATATCTAATTGCACTGACCGAGGATGAGTTTC

>NC_010803|5|3|1015192-1016257|CRT
CTTTATATCTAATTGCACTCATTGAGGATTGAAAC	CTGCCCTGTATTGTCTCTTCGTCCGGATCGTTGCCGGGTT
CTTTATATCTAATTGCACTCATTGAGGATTGAAAC	TGTCGATGACGCTATCCATCCTGCCGTTCCATTACTG
CTTTATATCTAATTGCACTCATTGAGGATTGAAAC	TCTAACTATAACGAAGCCGGTCGCCAACGTTACACCG
CTTTATATCTAATTGCACTCATTGAGGATTGAAAC	TTAATAGCCCTTTTTCTTCCTTCTTTTTTAATAAAA
CTTTATATCTAATTGCACTCATTGAGGATTGAAAC	TAAAGTTAGGTTTTGATTGTTTACATATACCATGATA
CTTTATATCTAATTGCACTCATTGAGGATTGAAAC	AAAGCCGCAACAGGATTTGCTGACATCAACATAGCTGCTG
CTTTATATCTAATTGCACTCACTGAGGATTGAAAC	TCCTTCGAGAAGCGCTCCGGTTTGCTTGAAAATATCCAGCGC
CTTTATATCTAATTGCACTCACTGAGGATTGAAAC	TGTGTTTAGTGATTTTTGAAGATGGAAATTGTAAAAAACT
CTTTATATCTAATTGCACTCACTGAGGATTGAAAC	ATCCCGCACCGCCGACCTGCGGTTAAACTCCTCATCA
CTTTATATCTAATTGCACTCACTGAGGATTGAAAC	CTTTCCCGTAGTAGAGAGCGCGATGCTGATATGCCGAATGCACAGAGA
CTTTATATCTAATTGCACTCACTGAGGATTGAAAC	TCAACGAATCTGTCCCTTTCCTGCTGCACCTGCCGA
CTTTATATCTAATTGCACTCACCGAGGATTGAAAC	GCAGTGGACTTTATGGTGTATTCCATCCAGCCGAA
CTTTATATCTAATTGCACTCACCGAGGATTGAAAC	GTCCGTGCTCCAGCCTCCGGCAGCCTGATTTTTCCAGTC
CTTTATATCTAATTGCACTCACCGAGGATTGAAAC	GAACAAATGAACCGCGTTCCAACACCCCAAGGAACAC
CTTTATATCTAATTGCACTGACCGAGGATGAGTTT

Protein	Signature genes	Signature genes Name	Protein_function
NC_010803.1\|WP_150081559.1\|1027956_1029167_+\|IS3-family-transposase	unknown	unknown	gnl\|CDD\|222853
NC_010803.1\|WP_081429877.1\|1030822_1031194_+\|hypothetical-protein	cas6	pfam01881_cas6_CAS-I:CAS-III	gnl\|CDD\|376642
NC_010803.1\|WP_012465889.1\|1018683_1019955_+\|hypothetical-protein	cmr6gr7	mkCas0142_cmr6gr7_CAS-III-C	gnl\|CDD\|187857
NC_010803.1\|WP_012465894.1\|1024985_1026407_+\|hypothetical-protein	unknown	unknown	unknown
NC_010803.1\|WP_041465671.1\|1007634_1008807_-\|ATP-binding-protein	unknown	unknown	gnl\|CDD\|224292
NC_010803.1\|WP_012465881.1\|1005837_1006113_-\|DUF2442-domain-containing-protein	unknown	unknown	gnl\|CDD\|378424
NC_010803.1\|WP_012465882.1\|1006123_1006384_-\|DUF4160-domain-containing-protein	unknown	unknown	gnl\|CDD\|379344
NC_010803.1\|WP_012465890.1\|1019951_1022768_+\|CRISPR-associated-protein-Csx11	cas10	cd09701_cas10_CAS-III-C	gnl\|CDD\|187832
NC_010803.1\|WP_012465874.1\|999391_1000753_-\|FAD-dependent-oxidoreductase	unknown	unknown	gnl\|CDD\|131778
NC_010803.1\|WP_012465876.1\|1001335_1001863_+\|Lrp/AsnC-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|224439
NC_010803.1\|WP_012465892.1\|1023749_1024124_+\|hypothetical-protein	cmr5gr11	mkCas0060_cmr5gr11_CAS-III-C	unknown
NC_010803.1\|WP_012465898.1\|1032704_1033211_+\|hypothetical-protein	unknown	unknown	unknown
NC_010803.1\|WP_012465878.1\|1004134_1004554_-\|YjbQ-family-protein	unknown	unknown	gnl\|CDD\|223509
NC_010803.1\|WP_150081556.1\|1001924_1004069_+\|glutamine-synthetase-III	unknown	unknown	gnl\|CDD\|226477
NC_010803.1\|WP_012465893.1\|1024123_1024927_+\|hypothetical-protein	cmr3gr5	mkCas0067_cmr3gr5_CAS-III-C	unknown
NC_010803.1\|WP_012465891.1\|1022760_1023753_+\|hypothetical-protein	cmr4gr7	COG1336_cmr4gr7_CAS-III-C	gnl\|CDD\|224255
NC_010803.1\|WP_012465887.1\|1012745_1014941_+\|CRISPR-associated-endonuclease-Cas1	cas1	cd09634_cas1_CAS-I:CAS-II:CAS-III:CAS-V	gnl\|CDD\|376633
NC_010803.1\|WP_012465886.1\|1012341_1012626_+\|CRISPR-associated-endonuclease-Cas2	cas2	pfam09827_cas2_CAS-I:CAS-II:CAS-III	gnl\|CDD\|187856
NC_010803.1\|WP_012465888.1\|1017691_1018687_+\|type-III-B-CRISPR-module-RAMP-protein-Cmr1	cmr1gr7	cd09657_cmr1gr7_CAS-III-C	gnl\|CDD\|273859
NC_010803.1\|WP_041465887.1\|1006596_1007577_+\|transposase	unknown	unknown	gnl\|CDD\|376616

Protein	Function_ID	Function_description	E-value
NC_010803.1\|WP_150081559.1\|1027956_1029167_+\|IS3-family-transposase	gnl\|CDD\|222853	PHA02517, PHA02517, putative transposase OrfB; Reviewed.	7.70772e-45
NC_010803.1\|WP_081429877.1\|1030822_1031194_+\|hypothetical-protein	gnl\|CDD\|376642	pfam01881, Cas_Cas6, CRISPR associated protein Cas6. This group of families is one of several protein families that are always found associated with prokaryotic CRISPRs, themselves a family of clustered regularly interspaced short palindromic repeats, DNA repeats found in nearly half of all bacterial and archaeal genomes. These DNA repeat regions have a remarkably regular structure: unique sequences of constant size, called spacers, sit between each pair of repeats. It has been shown that the CRISPRs are virus-derived sequences acquired by the host to enable them to resist viral infection. The Cas proteins from the host use the CRISPRs to mediate an antiviral response. After transcription of the CRISPR, a complex of Cas proteins termed Cascade cleaves a CRISPR RNA precursor in each repeat and retains the cleavage products containing the virus-derived sequence. Assisted by the helicase Cas3, these mature CRISPR RNAs then serve as small guide RNAs that enable Cascade to interfere with virus proliferation. Cas5 contains an endonuclease motif, whose inactivation leads to loss of resistance, even in the presence of phage-derived spacers.	3.22721e-13
NC_010803.1\|WP_012465889.1\|1018683_1019955_+\|hypothetical-protein	gnl\|CDD\|187857	cd09726, RAMP_I_III, CRISPR/Cas system-associated RAMP superfamily protein. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; RAMP superfamily proteins.	5.45249e-10
NC_010803.1\|WP_041465671.1\|1007634_1008807_-\|ATP-binding-protein	gnl\|CDD\|224292	COG1373, COG1373, Predicted ATPase (AAA+ superfamily) [General function prediction only].	2.1081e-62
NC_010803.1\|WP_012465881.1\|1005837_1006113_-\|DUF2442-domain-containing-protein	gnl\|CDD\|378424	pfam10387, DUF2442, Protein of unknown function (DUF2442). This family of bacterial and fungal proteins has several members annotated as being putative molybdopterin-guanine dinucleotide biosynthesis protein A; however this could not be verified. Hence the function is not known. This family also includes the DUF3532 that was found to be related and was merged into this family. Members of this family also fall into the NE0471 N-terminal domain-like superfamily, a family of proteins with a unique fold in SCOP:143880.	8.02539e-14
NC_010803.1\|WP_012465882.1\|1006123_1006384_-\|DUF4160-domain-containing-protein	gnl\|CDD\|379344	pfam13711, DUF4160, Domain of unknown function (DUF4160).	2.24855e-18
NC_010803.1\|WP_012465890.1\|1019951_1022768_+\|CRISPR-associated-protein-Csx11	gnl\|CDD\|187832	cd09701, Cas10_III, CRISPR/Cas system-associated protein Cas10. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Multidomain protein with permuted HD nuclease domain, inactivated palm domain and Zn-ribbon; signature gene for type III.	0
NC_010803.1\|WP_012465874.1\|999391_1000753_-\|FAD-dependent-oxidoreductase	gnl\|CDD\|131778	TIGR02731, Phytoene_dehydrogenase_chloroplastic/chromoplastic, phytoene desaturase. Plants and cyanobacteria (and, supposedly, Chlorobium tepidum) have a conserved pathway from two molecules geranylgeranyl-PP to one of all-trans-lycopene. Members of this family are the enzyme pytoene desaturase (also called phytoene dehydrogenase). This model does not include the region of the chloroplast transit peptide in plants. A closely related family, excluded by this model, is zeta-carotene desaturase, another enzyme in the same pathway. [Biosynthesis of cofactors, prosthetic groups, and carriers, Other].	3.59526e-131
NC_010803.1\|WP_012465876.1\|1001335_1001863_+\|Lrp/AsnC-family-transcriptional-regulator	gnl\|CDD\|224439	COG1522, Lrp, Transcriptional regulators [Transcription].	5.28431e-34
NC_010803.1\|WP_012465878.1\|1004134_1004554_-\|YjbQ-family-protein	gnl\|CDD\|223509	COG0432, COG0432, Uncharacterized conserved protein [Function unknown].	1.5103e-52
NC_010803.1\|WP_150081556.1\|1001924_1004069_+\|glutamine-synthetase-III	gnl\|CDD\|226477	COG3968, COG3968, Uncharacterized protein related to glutamine synthetase [General function prediction only].	0
NC_010803.1\|WP_012465891.1\|1022760_1023753_+\|hypothetical-protein	gnl\|CDD\|224255	COG1336, COG1336, CRISPR system related protein, RAMP superfamily [Defense mechanisms].	8.81904e-44
NC_010803.1\|WP_012465887.1\|1012745_1014941_+\|CRISPR-associated-endonuclease-Cas1	gnl\|CDD\|376633	pfam01867, Cas_Cas1, CRISPR associated protein Cas1. Clustered regularly interspaced short palindromic repeats (CRISPRs) are a family of DNA direct repeats found in many prokaryotic genomes. This family of proteins corresponds to Cas1, a CRISPR-associated protein. Cas1 may be involved in linking DNA segments to CRISPR.	1.49377e-104
NC_010803.1\|WP_012465886.1\|1012341_1012626_+\|CRISPR-associated-endonuclease-Cas2	gnl\|CDD\|187856	cd09725, Cas2_I_II_III, CRISPR/Cas system-associated protein Cas2. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas2 is present in majority of CRISPR/Cas systems along with Cas1; RNAse specific to U-rich regions; Possesses an RRM/ferredoxin fold.	7.02181e-28
NC_010803.1\|WP_012465888.1\|1017691_1018687_+\|type-III-B-CRISPR-module-RAMP-protein-Cmr1	gnl\|CDD\|273859	TIGR01894, hypothetical_protein, CRISPR type III-B/RAMP module RAMP protein Cmr1. CRISPR is a term for Clustered, Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins. This model represents the region of stongest conservation, the N-terminal half, of one such family, represented by TM1795 from Thermotoga maritima. This protein is the first of a set of six genes, mostly from the RAMP superfamily, that we designated the CRISPR-associated RAMP module.	9.41908e-19
NC_010803.1\|WP_041465887.1\|1006596_1007577_+\|transposase	gnl\|CDD\|376616	pfam01797, Y1_Tnp, Transposase IS200 like. Transposases are needed for efficient transposition of the insertion sequence or transposon DNA. This family includes transposases for IS200 from E. coli.	3.02347e-06

>NC_010803.1|WP_012465887.1|1012745_1014941_+|CRISPR-associated-endonuclease-Cas1
MGWLYNQMAMPETIFQAWYKVASNDGRPGWDNKSIEDYSLQLEENLKALSQALLTGTYKQGPLMKLVLLKPDGKDRVLLIPGVMDRVAQTAAAIVLSPIIEAELGNCTFAYRPGISREGAAREIDRLHREGYQWVLDADIRSFFDNVRHDLLFQRLVELIDDKEMISLLHRWLTAEIVDGINPRIQNTMGLPQGCPISPALANLYLDRFDETMEKEGFKLVRFADDYLVLCKTRPKAEAALKLSETALAELKLELHSDKTRITTFAEGFKYLGYLFIRALVIPTKMHPEEWYDKLGKFKLRKKSEHALPSDPDAMTGETAKFELETDQGEKIELTKNELLQTEFGCKLLESLDKKQLSVDEFLEKVARQDEERQKEKRDALKKLYSPFLNTLYLQEQGSLMRKDGERFSIEKDGAVINEVIVRRIEQVVVFGNIALTTPVMQYCMQNEIPVTFLSQHGKYFGRLESTMADNAEMQRYHFLRSIDEPFALETARSIVSAKIGNSRTMIRRRKSVMQDCDGTLQSKMTCNLDIMADLLLKAETSTDIDVLRGLEGKASALYFECYGMFFSKNLPFHTASFLRVRRPPTDPVNSLLSFGYSLLHTNVFSMVQMSGLNPYIGFLHAERKGNPALVNDLVEEFRTVIDSLVLYTINRGLLHENDFYYRKDQPGCFLSNDARKRFLQIFETRMWQESRDGYTGKTLNFRRHIEKQVRIMRDVISGTRTQYDPYKLVW
>NC_010803.1|WP_012465886.1|1012341_1012626_+|CRISPR-associated-endonuclease-Cas2
MQFILVTYDIENDRRRTKIHKVLEGYGISVQYSVFECFLSDNDYAGLRQRLQNLLDPNHPLDSIRYYRLCRNCVEIVDVDGNRPFEIDSPFVIS
>NC_010803.1|WP_041465671.1|1007634_1008807_-|ATP-binding-protein
MIHRTLTRNLQDALEVYPAVALLGPRQSGKTTLALEVGKSFDALYLDLESEQDRARLANPELYLSDHLERLVILDEVHRTPGLFPVLRGLIDRSRRAGRRSGLYLLLGSASLDLLKQTGESLAGRISYIELTPFTILEAGTGNVDKLWTRGGFPDSMLASTEPISFRWRQDFIRTYLERDIPQFGPRIAAETLRRFWTMLAWHQGGMVNMSQFSRSLGIDVKTVSNYMDLLVDLLLVRRLPPWHENPGKRLVRTPKVFIRDSGLTHALLGIADKDMLLSHPVVGQSWECFVIENILDSAPADVQGYFYRTGGGAEIDLLLVWPDGKRWAVEVKRSLTPKLERGFHSAHADLGPERSFVVYPGTERYRISETVEAISLADLALELQLANKR
>NC_010803.1|WP_041465887.1|1006596_1007577_+|transposase
MPRGARLDAPGTLHHVMVRGTEGMAIVQDDEDREGFVGRLGMVVAATGTSMYAWALMSNHAHMLLRSGPSGLSTFMRKFLTGYASFYNRRHKRHGHLFQNRYKSIVCEEEPYFLRLVSYIHLNPLRAGLVRSMEELDGYRWSGHAVVLNRIRHDWQNREAVLGYFGKRESSAMQAYREFVATESGLGRQPELTGGGLIRSIGGWSEVKSLRKRSEKQFSDERILGSGEFVKEILKEAEDGVKERLPAVSLECEAQERLQRLCEEKGVAVKVMHAGSRTRQCSAIRRQLAEEFVEELGMSYAGAARILGISASGVNQILMRDRKKLQ
>NC_010803.1|WP_012465882.1|1006123_1006384_-|DUF4160-domain-containing-protein
MPEISRFFGIIIRMFYDEHNPPHFHAEFQGKSSVFDFQGNILKGSLGSRTAVKLVREWIDLHTDDLLADWELASSNKEIKPIEPLN
>NC_010803.1|WP_012465881.1|1005837_1006113_-|DUF2442-domain-containing-protein
MWNMNDVIGITYVGGYTYHVTFDDGLRGDIDFSEYPEKGPVFAPLKELGFFRKAFIEGGTIAWPNGADIAPESLYEKLLQKEQNRECVVRQ
>NC_010803.1|WP_012465878.1|1004134_1004554_-|YjbQ-family-protein
MKSYHKELWMQVPARMDFVNITGDVEKALLESGIQEGLCLVNAMHITASVFINDNEPGLHQDYKRWLEELAPHEPISRYRHNMTGEDNGDAHHKRQIMGREVVVAVTKGKLHFGAWEQIFYGEFDGMRKKRVLVKIIGE
>NC_010803.1|WP_150081556.1|1001924_1004069_+|glutamine-synthetase-III
MNMESKVPVSSYFGAMTFDQKAMRARLPKDEFKALQDTIRAGKKITGEIAGVVAHGMKEWAMEQGATHYTHWFQPMTGSTAEKHDAFLSIDRDGTPIERFSGEQLIQGEPDASSFPSGGMRTTFEARGYTAWDPSSPAFLMKGGTGLTLCIPTVFISYHGEALDSKTPLLRSMDAVSNSAIRLLNVLGTTGISRVKTFAGCEQEYFLIDKKFYSERPDLIMCGRTLLGALPPKGQQLEDHYFGSIPDRVLEFMQDVEHELYLLGIPAKTRHNEVAPHQFEIAPIFEEANIAVDHNLLVMEVMRKVADKKGFALLLTEKPFAGINGSGKHNNWSIGTDTGINLLDPGDTPTENINFLVFLVAVLKGVYKRADVLRMSIASTGNDHRLGANEAPPAVVTVFLGEQLETVLDAIESGKVDLKTEKQVLNLGLSQVPLLNKDYTDRNRTSPFAFTGNKFEFRAVGSSQAASVPNMVLNTLMAEALDELTDAIEAKIAAGKDRDSAVLEAIREGITATKDIRYPGDNYSEALQQAAKERGLPNLKNTPQALRTLEKSDVKAMFVKYGVLTEQEIESRLNIRLERYVKGIDIEARTLQLMLKTLVIPDVSEYQGDIGNSFNNLLAASEAIGLSEGAIASQANHFKNLAENLSSLIDLTAELDEAVEKIETIEGEFGKADFCADELLPLMNAVRAVADRLELMVDRSRWQLPTYSEMLFEH
>NC_010803.1|WP_012465876.1|1001335_1001863_+|Lrp/AsnC-family-transcriptional-regulator
MSGHLDLIDLKIIESLGENGRLRLSELAEVVALSIPSVSERLDKLQKNGIIRSFTMEVDERQLGFDIQAFVRVRIDSSKHYKSFMEHVLQEDEIMECFSVTGEGSHILKVMTHNTSSLEKFLSRIQSWPGVLETNTSFVLSQLKRTRKISAEIVRNNLQDRQVLITFDEKKSRKV
>NC_010803.1|WP_012465874.1|999391_1000753_-|FAD-dependent-oxidoreductase
MKIAIFGAGVAGLSAAIELVDRGHAVELYEKRKVLGGKVSVWKDNDGDSIESGLHIVFGGYEQLQQYMKKVGAAENYLWKEHSLIYAEPDGKQSFFKKANLPSPWAEVVGGMQADFLTMWDKISLIKGLYPALAGNEEYFRSQDHMTYSEWHRLRGASEHSLEKLWRAIALAMNFIEPNVISARPMITIFKYFGTDYAATKFAFFRKNPGDSMIEPMRQYIQTRGGRIFVDAKLNRFELNSDETVKCAVLQDGQKIEADAYISALPVHNIKNIVPGEWFNHAYFRNLHQFVGSPVANCQLWFDRKITATDNLMFSQGTTFATFADVSITCPDDFQKGMGSAEGGSVMSLVLAPAHQLMDLPNDVITRLVMKDIHDRFPLSRDAKLLKSTIVKIPQSVYKAVPDVDKFRPDQASPVKNFFLAGDYTYQRYLASMEGAALSGRQAAEKLHTRLGG
>NC_010803.1|WP_012465888.1|1017691_1018687_+|type-III-B-CRISPR-module-RAMP-protein-Cmr1
MKANIELRTLTPIWTGGVETGKMERIHETGIIGNLRWWYEAIVRGLGGEACDPTTHSCAYDREKPNNGLCDVCQVFGATGWRRRFNLSVHETQMQPQSVTHPMRANRIYQNRQGKNIPPTWYFPNPPQGGNFLIEVQSSSSVFSVELVQGLIQLSVDWTALGARTQMGFGVTSLVRGRLNANPFNYLRLTCCGSSNNLPSLQNMFFAQIEKENITDQETFNIKYDLRRLFAGNQDVRHFVMGTVQEERIAAKIHVSRPYANGLIRVWGWVPVDANVWNDKWNRDGVLTQIKNHLESNYALKTWREFNNDRDINQQYSDVRAYLHSLWESKK
>NC_010803.1|WP_012465889.1|1018683_1019955_+|hypothetical-protein
MNQTFKSFVEPFPHTISEISELLSNLSQAEQAIKVNKRNKEVRQQYENQAKDLHRQLLTHKDCSLIYNYMEATGIADKDTFRSTWAREKLKVDSDELPDFLKPPLLDDLSCLPVGSFYIQFKFTLLKPYISRDDNAFYLVDNSIVREKVFRFPMVRSTAWKGSLRHALWQMDGYQKEDQQDQQIKRLFGTANDEQPEEGNSGRFYFYPSFFTLNSLEVINPHGRKTRVGTTPILFESVPIGAEATFTLLYSPLDRIGREDVETRQQVIADLKLVAEGLRALFIVYGFGAKTSSGFGLANDAIENGSLILNLPSFVFPQAETVQVQTPEDVFLKYMDESGYLKTVFSGGGDYGLMSNKEYGEKREQLGGGYLTEFKAFRKWYGENGEQWQKSIKEKSSATNYPQLRFKSLSQLAERMRQTGGEA
>NC_010803.1|WP_012465890.1|1019951_1022768_+|CRISPR-associated-protein-Csx11
MSQLDQLIQHRDAILLAEAIGWLHDYWKCSEEQLQKQSPINDKDLKLKPKEIALQEITKRFSSLGNTLLEISTAKESLSDLLNQWHGKAGNAGASFLLQYLSRCHNTAHFDKQDPLKSGRQNYPDTQISSAFGFETAVGSCLSAQLWALPWDSLITNHDHERSTLRQAVQSLFSNVGADTRRPINEISLWDWGLLVGALYKTALAAVALGQSPVTHDLRWRLLGIRTDALAYFSNVSRLPDLVARQNTLQTAINNVQTLLETVYPVATEVYRDENGSLYVVPDMANLLGLQDSSDKTLLSLIKEQFACDGEIVPDITLDPNPWWGQDPVRAGNDEIPPAGSILSSPVTWKSDADAVREAWKEQRQTVCPICGLRSCVNRQLDYCQICGDRRKGRVKEWLQEQNKTIWIDEVADRNGRLALITGTFNLTNWLDGSLVETMLVKEPTDSNPSVPKIPSFARLRRIWQTTRTFWKQSQSDIDQHLTDARRRLTIRLANSPKLTPNQTYELDLGGQTRMSVLWDGNHLLSIDNLSYTASQLGFPLNNFETKENWTPEDLALDVCAWVKQHKESWSGQKQVFQLFSDEEKNKQFDIQIGDMGYQDAAYASTIPILAEPRTFMVLVPADCALDLIHAIKTKYEREIGKVRNRLSLHLGAVYFHRRTPLRAALDAGRRMLKYDLGQMKDEVWIVKEDAKRELLPLEKQYLAEEENKQLAEAVAVKLEQNGRFLTWYVPARMGDGKTDDSWYPYVFIQNDVSKRKHIFKALRPKSDHTTEECWLIHATKLQAGDRVYFTPATFDFQWLGSSGERFEIAYENGKRRNQPMRPYLLDELTTIQQAWKVIAGKGGLTANQIYALRDLIEIKRENWQPSANHWVQDCYSQTGMFWLFCRDVINNANWKNKPVDEEINLLINWAVSGLLADVIHLHMGVMKQKPQREENNE
>NC_010803.1|WP_012465891.1|1022760_1023753_+|hypothetical-protein
MSNQNSNHCHKQRFLLQTLDPVHVGTGGNRLGRVDLSIVREPGTRLPKIPGTSLHGAIRQYAAVCYESLRCAGAGQGNESKGKEPHCRDAQCPVCYTFGYMNGQDGGQSGQISISDARLLLFPVYSLAGPVWVTSPSILSEFGVPTNDPCDQVCLPDVLTSQEHLNLGWLMLAKASDPFNWPDAIKGVPVEITSRAVLVSDKLFSQIVNSNLEVRTSVSIDPETGAAVDKALFTYEAIPRATILWMDVIEDDFRGVFPGTDKKCRTTIDEKEGTKKKTYEHNAGDPLIEPWNRPLDVVKSALKLAEMLGIGGMGTRGFGRVRLLNEGSES
>NC_010803.1|WP_012465892.1|1023749_1024124_+|hypothetical-protein
MTQLNLDQLAARYAQKIVEKGKADIENPVTKALGVLQEQGVYACILYLLANKHDNILKPLYQLVGELPGFRGNEKMPDEKIDSKEMLKFYGDCVCSDLDTLLLVKELYEQTLIYARYGAKAAGK
>NC_010803.1|WP_012465893.1|1024123_1024927_+|hypothetical-protein
MTWQKYELVFRMLAPLHIGYRTAGNLMQTRSYVPGRVLWAALTTRLTRDEENGTDGLRYIEIGQQVQDHFRFTYLYPATQNGNGYKTYYPWEKDFDYLFLNSYASTSLNYASQSAEEAMLHETEFIAPHTRTGQSVYLVGNVYTKTNLPTPLENWPKALEKLQLGAERGYGWGRVRTVSCDSQGERFYNEPVAELFDGHITAHLKAEKVSGIVGPVEPLIGWERNNDINRKSNWRLTEEAIICYVPGAKVTVDGNYIIGPNGVCGIN
>NC_010803.1|WP_012465894.1|1024985_1026407_+|hypothetical-protein
MVALHDHFVKLVIPFEYSKEYTDAITAINAAVCWEPNTRVPRDMFLHIKHLISSETSNNSIGVSYVLTAAGRLTCNFPLLKDQAGVLLKKGSGDPELPDFEIKFTVPEVYLFLFETQVGFIILDIKYIESGSLEVVEMANHQLKKIGLSRSFICRDGEKPEKAKKGIGFFDRFFESLKPLVSLVSFFEEQERMLRHLYLFNYLILDHLPESDTEKNNFIVETLFRLRNGFHAHYRPSKKEYDPESNSQVLSFVYNIFWGVSQEGVACVACLTGDSRQTHFLTHIFNYNVENSYFYLYILAMAQRFSLLIIAKKTADIPPEIRGSIEELKNKKEIICAIDALRQDIVLYGLRINYSQVSYNFHYTLFYEKLREVFRLDYQHTELDTEVKNLGALIDIIEQKKRINFELNAAVALLVFAVVSVLSDGLSFFQFMNLFDTHRPLLSLTGLILVVVIVLMLFRYFLKKDVLFNIRKR
>NC_010803.1|WP_150081559.1|1027956_1029167_+|IS3-family-transposase
MSEKQRKSFTAQFKAKVALEAIRGEKTLNEIGREFGIHPNLVGQWKREVQEHAAGLFEAKRGPKPVDPLADPEKLYAEIGRLKVELNWLKKKGRSVPMKARKNWISDKEQLSVSTQCELAGVTRSGYYGQSKSLMPNTEDLELMKLIDEEYTRHPFYGSRRMKQVLLTQGRKVNRKRVQRLMRNLGLAGMAPGPNTSKPHPQHKIYPYLLRGLSITRPNHVWSTDVTYCRLPGGFMYLTAVIDWYSRKVLAWRLSNSLDSSYCVDCLEEAIRKYGTPEIFNTDQGVQYTSDAFTSVLKSHEIRISMDGRGRALDNVFVERLWRNVKQEDLYLKGYETAVEMMRGFAEYFRFYNIERPHQSLGYKTPDEVYESAIGGGARIVDKFSKSVSEGSSEATGPQQEAA
>NC_010803.1|WP_081429877.1|1030822_1031194_+|hypothetical-protein
MIANFRNWLILYFRLQVLQENLCRKYEALHGRPYAADNSTFRFTLDHDYADRKNGKIQKLITIKEGRPDETKVKGLLAPFRLEAPLELMEVGYECGFGERNSQGFGMVKVDEDCGGKSVASSQ
>NC_010803.1|WP_012465898.1|1032704_1033211_+|hypothetical-protein
MPEVFQYPMTYPAWWMDYYYIATWCLGMLFLGTGWALFFRYGKFSYGVDLGCFWKTALLIILTTIALGGPNYYNTRFVGEHGQDGDSIKIAGEELLYLDRKGNEKKFALDDITAVYQEPITYNPPPKIFIVAGKGKVKDSLFVTRNLKGFETFLVSLSTRTGVPVKRP

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Crispr_ID: NC_010803_6

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_010803_6

1016657-1016762

TypeIII

Consensus_repeat	Method
CTTTATATCTAATTGCACTCATTGAGGATTGAAAC	CRISPRCasFinder

1 spacers

cas1,cas2,cmr1gr7,cmr6gr7,cas10,cmr4gr7,cmr5gr11,cmr3gr5,cas6

The CRISPR arrays of NC_010803_6

>merge|NC_010803|6|1016657-1016762|CRISPRCasFinder
TTACATATCTAATTGCACTCATTGAGGATTGAAACATATCGATCGGGGTACCTTCCGTCAGTTTGGCGACCCTTTATATCTAATTGCACTCATTGAGGATAAGATT

>NC_010803|6|6|1016657-1016762|CRISPRCasFinder
TTACATATCTAATTGCACTCATTGAGGATTGAAAC	ATATCGATCGGGGTACCTTCCGTCAGTTTGGCGACC
CTTTATATCTAATTGCACTCATTGAGGATAAGATT

Protein	Signature genes	Signature genes Name	Protein_function
NC_010803.1\|WP_150081559.1\|1027956_1029167_+\|IS3-family-transposase	unknown	unknown	gnl\|CDD\|222853
NC_010803.1\|WP_081429877.1\|1030822_1031194_+\|hypothetical-protein	cas6	pfam01881_cas6_CAS-I:CAS-III	gnl\|CDD\|376642
NC_010803.1\|WP_012465889.1\|1018683_1019955_+\|hypothetical-protein	cmr6gr7	mkCas0142_cmr6gr7_CAS-III-C	gnl\|CDD\|187857
NC_010803.1\|WP_012465894.1\|1024985_1026407_+\|hypothetical-protein	unknown	unknown	unknown
NC_010803.1\|WP_041465671.1\|1007634_1008807_-\|ATP-binding-protein	unknown	unknown	gnl\|CDD\|224292
NC_010803.1\|WP_012465881.1\|1005837_1006113_-\|DUF2442-domain-containing-protein	unknown	unknown	gnl\|CDD\|378424
NC_010803.1\|WP_012465882.1\|1006123_1006384_-\|DUF4160-domain-containing-protein	unknown	unknown	gnl\|CDD\|379344
NC_010803.1\|WP_012465890.1\|1019951_1022768_+\|CRISPR-associated-protein-Csx11	cas10	cd09701_cas10_CAS-III-C	gnl\|CDD\|187832
NC_010803.1\|WP_012465874.1\|999391_1000753_-\|FAD-dependent-oxidoreductase	unknown	unknown	gnl\|CDD\|131778
NC_010803.1\|WP_012465876.1\|1001335_1001863_+\|Lrp/AsnC-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|224439
NC_010803.1\|WP_012465892.1\|1023749_1024124_+\|hypothetical-protein	cmr5gr11	mkCas0060_cmr5gr11_CAS-III-C	unknown
NC_010803.1\|WP_012465898.1\|1032704_1033211_+\|hypothetical-protein	unknown	unknown	unknown
NC_010803.1\|WP_012465878.1\|1004134_1004554_-\|YjbQ-family-protein	unknown	unknown	gnl\|CDD\|223509
NC_010803.1\|WP_150081556.1\|1001924_1004069_+\|glutamine-synthetase-III	unknown	unknown	gnl\|CDD\|226477
NC_010803.1\|WP_012465893.1\|1024123_1024927_+\|hypothetical-protein	cmr3gr5	mkCas0067_cmr3gr5_CAS-III-C	unknown
NC_010803.1\|WP_012465891.1\|1022760_1023753_+\|hypothetical-protein	cmr4gr7	COG1336_cmr4gr7_CAS-III-C	gnl\|CDD\|224255
NC_010803.1\|WP_012465887.1\|1012745_1014941_+\|CRISPR-associated-endonuclease-Cas1	cas1	cd09634_cas1_CAS-I:CAS-II:CAS-III:CAS-V	gnl\|CDD\|376633
NC_010803.1\|WP_012465886.1\|1012341_1012626_+\|CRISPR-associated-endonuclease-Cas2	cas2	pfam09827_cas2_CAS-I:CAS-II:CAS-III	gnl\|CDD\|187856
NC_010803.1\|WP_012465888.1\|1017691_1018687_+\|type-III-B-CRISPR-module-RAMP-protein-Cmr1	cmr1gr7	cd09657_cmr1gr7_CAS-III-C	gnl\|CDD\|273859
NC_010803.1\|WP_041465887.1\|1006596_1007577_+\|transposase	unknown	unknown	gnl\|CDD\|376616

Protein	Function_ID	Function_description	E-value
NC_010803.1\|WP_150081559.1\|1027956_1029167_+\|IS3-family-transposase	gnl\|CDD\|222853	PHA02517, PHA02517, putative transposase OrfB; Reviewed.	7.70772e-45
NC_010803.1\|WP_081429877.1\|1030822_1031194_+\|hypothetical-protein	gnl\|CDD\|376642	pfam01881, Cas_Cas6, CRISPR associated protein Cas6. This group of families is one of several protein families that are always found associated with prokaryotic CRISPRs, themselves a family of clustered regularly interspaced short palindromic repeats, DNA repeats found in nearly half of all bacterial and archaeal genomes. These DNA repeat regions have a remarkably regular structure: unique sequences of constant size, called spacers, sit between each pair of repeats. It has been shown that the CRISPRs are virus-derived sequences acquired by the host to enable them to resist viral infection. The Cas proteins from the host use the CRISPRs to mediate an antiviral response. After transcription of the CRISPR, a complex of Cas proteins termed Cascade cleaves a CRISPR RNA precursor in each repeat and retains the cleavage products containing the virus-derived sequence. Assisted by the helicase Cas3, these mature CRISPR RNAs then serve as small guide RNAs that enable Cascade to interfere with virus proliferation. Cas5 contains an endonuclease motif, whose inactivation leads to loss of resistance, even in the presence of phage-derived spacers.	3.22721e-13
NC_010803.1\|WP_012465889.1\|1018683_1019955_+\|hypothetical-protein	gnl\|CDD\|187857	cd09726, RAMP_I_III, CRISPR/Cas system-associated RAMP superfamily protein. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; RAMP superfamily proteins.	5.45249e-10
NC_010803.1\|WP_041465671.1\|1007634_1008807_-\|ATP-binding-protein	gnl\|CDD\|224292	COG1373, COG1373, Predicted ATPase (AAA+ superfamily) [General function prediction only].	2.1081e-62
NC_010803.1\|WP_012465881.1\|1005837_1006113_-\|DUF2442-domain-containing-protein	gnl\|CDD\|378424	pfam10387, DUF2442, Protein of unknown function (DUF2442). This family of bacterial and fungal proteins has several members annotated as being putative molybdopterin-guanine dinucleotide biosynthesis protein A; however this could not be verified. Hence the function is not known. This family also includes the DUF3532 that was found to be related and was merged into this family. Members of this family also fall into the NE0471 N-terminal domain-like superfamily, a family of proteins with a unique fold in SCOP:143880.	8.02539e-14
NC_010803.1\|WP_012465882.1\|1006123_1006384_-\|DUF4160-domain-containing-protein	gnl\|CDD\|379344	pfam13711, DUF4160, Domain of unknown function (DUF4160).	2.24855e-18
NC_010803.1\|WP_012465890.1\|1019951_1022768_+\|CRISPR-associated-protein-Csx11	gnl\|CDD\|187832	cd09701, Cas10_III, CRISPR/Cas system-associated protein Cas10. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Multidomain protein with permuted HD nuclease domain, inactivated palm domain and Zn-ribbon; signature gene for type III.	0
NC_010803.1\|WP_012465874.1\|999391_1000753_-\|FAD-dependent-oxidoreductase	gnl\|CDD\|131778	TIGR02731, Phytoene_dehydrogenase_chloroplastic/chromoplastic, phytoene desaturase. Plants and cyanobacteria (and, supposedly, Chlorobium tepidum) have a conserved pathway from two molecules geranylgeranyl-PP to one of all-trans-lycopene. Members of this family are the enzyme pytoene desaturase (also called phytoene dehydrogenase). This model does not include the region of the chloroplast transit peptide in plants. A closely related family, excluded by this model, is zeta-carotene desaturase, another enzyme in the same pathway. [Biosynthesis of cofactors, prosthetic groups, and carriers, Other].	3.59526e-131
NC_010803.1\|WP_012465876.1\|1001335_1001863_+\|Lrp/AsnC-family-transcriptional-regulator	gnl\|CDD\|224439	COG1522, Lrp, Transcriptional regulators [Transcription].	5.28431e-34
NC_010803.1\|WP_012465878.1\|1004134_1004554_-\|YjbQ-family-protein	gnl\|CDD\|223509	COG0432, COG0432, Uncharacterized conserved protein [Function unknown].	1.5103e-52
NC_010803.1\|WP_150081556.1\|1001924_1004069_+\|glutamine-synthetase-III	gnl\|CDD\|226477	COG3968, COG3968, Uncharacterized protein related to glutamine synthetase [General function prediction only].	0
NC_010803.1\|WP_012465891.1\|1022760_1023753_+\|hypothetical-protein	gnl\|CDD\|224255	COG1336, COG1336, CRISPR system related protein, RAMP superfamily [Defense mechanisms].	8.81904e-44
NC_010803.1\|WP_012465887.1\|1012745_1014941_+\|CRISPR-associated-endonuclease-Cas1	gnl\|CDD\|376633	pfam01867, Cas_Cas1, CRISPR associated protein Cas1. Clustered regularly interspaced short palindromic repeats (CRISPRs) are a family of DNA direct repeats found in many prokaryotic genomes. This family of proteins corresponds to Cas1, a CRISPR-associated protein. Cas1 may be involved in linking DNA segments to CRISPR.	1.49377e-104
NC_010803.1\|WP_012465886.1\|1012341_1012626_+\|CRISPR-associated-endonuclease-Cas2	gnl\|CDD\|187856	cd09725, Cas2_I_II_III, CRISPR/Cas system-associated protein Cas2. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas2 is present in majority of CRISPR/Cas systems along with Cas1; RNAse specific to U-rich regions; Possesses an RRM/ferredoxin fold.	7.02181e-28
NC_010803.1\|WP_012465888.1\|1017691_1018687_+\|type-III-B-CRISPR-module-RAMP-protein-Cmr1	gnl\|CDD\|273859	TIGR01894, hypothetical_protein, CRISPR type III-B/RAMP module RAMP protein Cmr1. CRISPR is a term for Clustered, Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins. This model represents the region of stongest conservation, the N-terminal half, of one such family, represented by TM1795 from Thermotoga maritima. This protein is the first of a set of six genes, mostly from the RAMP superfamily, that we designated the CRISPR-associated RAMP module.	9.41908e-19
NC_010803.1\|WP_041465887.1\|1006596_1007577_+\|transposase	gnl\|CDD\|376616	pfam01797, Y1_Tnp, Transposase IS200 like. Transposases are needed for efficient transposition of the insertion sequence or transposon DNA. This family includes transposases for IS200 from E. coli.	3.02347e-06

>NC_010803.1|WP_012465887.1|1012745_1014941_+|CRISPR-associated-endonuclease-Cas1
MGWLYNQMAMPETIFQAWYKVASNDGRPGWDNKSIEDYSLQLEENLKALSQALLTGTYKQGPLMKLVLLKPDGKDRVLLIPGVMDRVAQTAAAIVLSPIIEAELGNCTFAYRPGISREGAAREIDRLHREGYQWVLDADIRSFFDNVRHDLLFQRLVELIDDKEMISLLHRWLTAEIVDGINPRIQNTMGLPQGCPISPALANLYLDRFDETMEKEGFKLVRFADDYLVLCKTRPKAEAALKLSETALAELKLELHSDKTRITTFAEGFKYLGYLFIRALVIPTKMHPEEWYDKLGKFKLRKKSEHALPSDPDAMTGETAKFELETDQGEKIELTKNELLQTEFGCKLLESLDKKQLSVDEFLEKVARQDEERQKEKRDALKKLYSPFLNTLYLQEQGSLMRKDGERFSIEKDGAVINEVIVRRIEQVVVFGNIALTTPVMQYCMQNEIPVTFLSQHGKYFGRLESTMADNAEMQRYHFLRSIDEPFALETARSIVSAKIGNSRTMIRRRKSVMQDCDGTLQSKMTCNLDIMADLLLKAETSTDIDVLRGLEGKASALYFECYGMFFSKNLPFHTASFLRVRRPPTDPVNSLLSFGYSLLHTNVFSMVQMSGLNPYIGFLHAERKGNPALVNDLVEEFRTVIDSLVLYTINRGLLHENDFYYRKDQPGCFLSNDARKRFLQIFETRMWQESRDGYTGKTLNFRRHIEKQVRIMRDVISGTRTQYDPYKLVW
>NC_010803.1|WP_012465886.1|1012341_1012626_+|CRISPR-associated-endonuclease-Cas2
MQFILVTYDIENDRRRTKIHKVLEGYGISVQYSVFECFLSDNDYAGLRQRLQNLLDPNHPLDSIRYYRLCRNCVEIVDVDGNRPFEIDSPFVIS
>NC_010803.1|WP_041465671.1|1007634_1008807_-|ATP-binding-protein
MIHRTLTRNLQDALEVYPAVALLGPRQSGKTTLALEVGKSFDALYLDLESEQDRARLANPELYLSDHLERLVILDEVHRTPGLFPVLRGLIDRSRRAGRRSGLYLLLGSASLDLLKQTGESLAGRISYIELTPFTILEAGTGNVDKLWTRGGFPDSMLASTEPISFRWRQDFIRTYLERDIPQFGPRIAAETLRRFWTMLAWHQGGMVNMSQFSRSLGIDVKTVSNYMDLLVDLLLVRRLPPWHENPGKRLVRTPKVFIRDSGLTHALLGIADKDMLLSHPVVGQSWECFVIENILDSAPADVQGYFYRTGGGAEIDLLLVWPDGKRWAVEVKRSLTPKLERGFHSAHADLGPERSFVVYPGTERYRISETVEAISLADLALELQLANKR
>NC_010803.1|WP_041465887.1|1006596_1007577_+|transposase
MPRGARLDAPGTLHHVMVRGTEGMAIVQDDEDREGFVGRLGMVVAATGTSMYAWALMSNHAHMLLRSGPSGLSTFMRKFLTGYASFYNRRHKRHGHLFQNRYKSIVCEEEPYFLRLVSYIHLNPLRAGLVRSMEELDGYRWSGHAVVLNRIRHDWQNREAVLGYFGKRESSAMQAYREFVATESGLGRQPELTGGGLIRSIGGWSEVKSLRKRSEKQFSDERILGSGEFVKEILKEAEDGVKERLPAVSLECEAQERLQRLCEEKGVAVKVMHAGSRTRQCSAIRRQLAEEFVEELGMSYAGAARILGISASGVNQILMRDRKKLQ
>NC_010803.1|WP_012465882.1|1006123_1006384_-|DUF4160-domain-containing-protein
MPEISRFFGIIIRMFYDEHNPPHFHAEFQGKSSVFDFQGNILKGSLGSRTAVKLVREWIDLHTDDLLADWELASSNKEIKPIEPLN
>NC_010803.1|WP_012465881.1|1005837_1006113_-|DUF2442-domain-containing-protein
MWNMNDVIGITYVGGYTYHVTFDDGLRGDIDFSEYPEKGPVFAPLKELGFFRKAFIEGGTIAWPNGADIAPESLYEKLLQKEQNRECVVRQ
>NC_010803.1|WP_012465878.1|1004134_1004554_-|YjbQ-family-protein
MKSYHKELWMQVPARMDFVNITGDVEKALLESGIQEGLCLVNAMHITASVFINDNEPGLHQDYKRWLEELAPHEPISRYRHNMTGEDNGDAHHKRQIMGREVVVAVTKGKLHFGAWEQIFYGEFDGMRKKRVLVKIIGE
>NC_010803.1|WP_150081556.1|1001924_1004069_+|glutamine-synthetase-III
MNMESKVPVSSYFGAMTFDQKAMRARLPKDEFKALQDTIRAGKKITGEIAGVVAHGMKEWAMEQGATHYTHWFQPMTGSTAEKHDAFLSIDRDGTPIERFSGEQLIQGEPDASSFPSGGMRTTFEARGYTAWDPSSPAFLMKGGTGLTLCIPTVFISYHGEALDSKTPLLRSMDAVSNSAIRLLNVLGTTGISRVKTFAGCEQEYFLIDKKFYSERPDLIMCGRTLLGALPPKGQQLEDHYFGSIPDRVLEFMQDVEHELYLLGIPAKTRHNEVAPHQFEIAPIFEEANIAVDHNLLVMEVMRKVADKKGFALLLTEKPFAGINGSGKHNNWSIGTDTGINLLDPGDTPTENINFLVFLVAVLKGVYKRADVLRMSIASTGNDHRLGANEAPPAVVTVFLGEQLETVLDAIESGKVDLKTEKQVLNLGLSQVPLLNKDYTDRNRTSPFAFTGNKFEFRAVGSSQAASVPNMVLNTLMAEALDELTDAIEAKIAAGKDRDSAVLEAIREGITATKDIRYPGDNYSEALQQAAKERGLPNLKNTPQALRTLEKSDVKAMFVKYGVLTEQEIESRLNIRLERYVKGIDIEARTLQLMLKTLVIPDVSEYQGDIGNSFNNLLAASEAIGLSEGAIASQANHFKNLAENLSSLIDLTAELDEAVEKIETIEGEFGKADFCADELLPLMNAVRAVADRLELMVDRSRWQLPTYSEMLFEH
>NC_010803.1|WP_012465876.1|1001335_1001863_+|Lrp/AsnC-family-transcriptional-regulator
MSGHLDLIDLKIIESLGENGRLRLSELAEVVALSIPSVSERLDKLQKNGIIRSFTMEVDERQLGFDIQAFVRVRIDSSKHYKSFMEHVLQEDEIMECFSVTGEGSHILKVMTHNTSSLEKFLSRIQSWPGVLETNTSFVLSQLKRTRKISAEIVRNNLQDRQVLITFDEKKSRKV
>NC_010803.1|WP_012465874.1|999391_1000753_-|FAD-dependent-oxidoreductase
MKIAIFGAGVAGLSAAIELVDRGHAVELYEKRKVLGGKVSVWKDNDGDSIESGLHIVFGGYEQLQQYMKKVGAAENYLWKEHSLIYAEPDGKQSFFKKANLPSPWAEVVGGMQADFLTMWDKISLIKGLYPALAGNEEYFRSQDHMTYSEWHRLRGASEHSLEKLWRAIALAMNFIEPNVISARPMITIFKYFGTDYAATKFAFFRKNPGDSMIEPMRQYIQTRGGRIFVDAKLNRFELNSDETVKCAVLQDGQKIEADAYISALPVHNIKNIVPGEWFNHAYFRNLHQFVGSPVANCQLWFDRKITATDNLMFSQGTTFATFADVSITCPDDFQKGMGSAEGGSVMSLVLAPAHQLMDLPNDVITRLVMKDIHDRFPLSRDAKLLKSTIVKIPQSVYKAVPDVDKFRPDQASPVKNFFLAGDYTYQRYLASMEGAALSGRQAAEKLHTRLGG
>NC_010803.1|WP_012465888.1|1017691_1018687_+|type-III-B-CRISPR-module-RAMP-protein-Cmr1
MKANIELRTLTPIWTGGVETGKMERIHETGIIGNLRWWYEAIVRGLGGEACDPTTHSCAYDREKPNNGLCDVCQVFGATGWRRRFNLSVHETQMQPQSVTHPMRANRIYQNRQGKNIPPTWYFPNPPQGGNFLIEVQSSSSVFSVELVQGLIQLSVDWTALGARTQMGFGVTSLVRGRLNANPFNYLRLTCCGSSNNLPSLQNMFFAQIEKENITDQETFNIKYDLRRLFAGNQDVRHFVMGTVQEERIAAKIHVSRPYANGLIRVWGWVPVDANVWNDKWNRDGVLTQIKNHLESNYALKTWREFNNDRDINQQYSDVRAYLHSLWESKK
>NC_010803.1|WP_012465889.1|1018683_1019955_+|hypothetical-protein
MNQTFKSFVEPFPHTISEISELLSNLSQAEQAIKVNKRNKEVRQQYENQAKDLHRQLLTHKDCSLIYNYMEATGIADKDTFRSTWAREKLKVDSDELPDFLKPPLLDDLSCLPVGSFYIQFKFTLLKPYISRDDNAFYLVDNSIVREKVFRFPMVRSTAWKGSLRHALWQMDGYQKEDQQDQQIKRLFGTANDEQPEEGNSGRFYFYPSFFTLNSLEVINPHGRKTRVGTTPILFESVPIGAEATFTLLYSPLDRIGREDVETRQQVIADLKLVAEGLRALFIVYGFGAKTSSGFGLANDAIENGSLILNLPSFVFPQAETVQVQTPEDVFLKYMDESGYLKTVFSGGGDYGLMSNKEYGEKREQLGGGYLTEFKAFRKWYGENGEQWQKSIKEKSSATNYPQLRFKSLSQLAERMRQTGGEA
>NC_010803.1|WP_012465890.1|1019951_1022768_+|CRISPR-associated-protein-Csx11
MSQLDQLIQHRDAILLAEAIGWLHDYWKCSEEQLQKQSPINDKDLKLKPKEIALQEITKRFSSLGNTLLEISTAKESLSDLLNQWHGKAGNAGASFLLQYLSRCHNTAHFDKQDPLKSGRQNYPDTQISSAFGFETAVGSCLSAQLWALPWDSLITNHDHERSTLRQAVQSLFSNVGADTRRPINEISLWDWGLLVGALYKTALAAVALGQSPVTHDLRWRLLGIRTDALAYFSNVSRLPDLVARQNTLQTAINNVQTLLETVYPVATEVYRDENGSLYVVPDMANLLGLQDSSDKTLLSLIKEQFACDGEIVPDITLDPNPWWGQDPVRAGNDEIPPAGSILSSPVTWKSDADAVREAWKEQRQTVCPICGLRSCVNRQLDYCQICGDRRKGRVKEWLQEQNKTIWIDEVADRNGRLALITGTFNLTNWLDGSLVETMLVKEPTDSNPSVPKIPSFARLRRIWQTTRTFWKQSQSDIDQHLTDARRRLTIRLANSPKLTPNQTYELDLGGQTRMSVLWDGNHLLSIDNLSYTASQLGFPLNNFETKENWTPEDLALDVCAWVKQHKESWSGQKQVFQLFSDEEKNKQFDIQIGDMGYQDAAYASTIPILAEPRTFMVLVPADCALDLIHAIKTKYEREIGKVRNRLSLHLGAVYFHRRTPLRAALDAGRRMLKYDLGQMKDEVWIVKEDAKRELLPLEKQYLAEEENKQLAEAVAVKLEQNGRFLTWYVPARMGDGKTDDSWYPYVFIQNDVSKRKHIFKALRPKSDHTTEECWLIHATKLQAGDRVYFTPATFDFQWLGSSGERFEIAYENGKRRNQPMRPYLLDELTTIQQAWKVIAGKGGLTANQIYALRDLIEIKRENWQPSANHWVQDCYSQTGMFWLFCRDVINNANWKNKPVDEEINLLINWAVSGLLADVIHLHMGVMKQKPQREENNE
>NC_010803.1|WP_012465891.1|1022760_1023753_+|hypothetical-protein
MSNQNSNHCHKQRFLLQTLDPVHVGTGGNRLGRVDLSIVREPGTRLPKIPGTSLHGAIRQYAAVCYESLRCAGAGQGNESKGKEPHCRDAQCPVCYTFGYMNGQDGGQSGQISISDARLLLFPVYSLAGPVWVTSPSILSEFGVPTNDPCDQVCLPDVLTSQEHLNLGWLMLAKASDPFNWPDAIKGVPVEITSRAVLVSDKLFSQIVNSNLEVRTSVSIDPETGAAVDKALFTYEAIPRATILWMDVIEDDFRGVFPGTDKKCRTTIDEKEGTKKKTYEHNAGDPLIEPWNRPLDVVKSALKLAEMLGIGGMGTRGFGRVRLLNEGSES
>NC_010803.1|WP_012465892.1|1023749_1024124_+|hypothetical-protein
MTQLNLDQLAARYAQKIVEKGKADIENPVTKALGVLQEQGVYACILYLLANKHDNILKPLYQLVGELPGFRGNEKMPDEKIDSKEMLKFYGDCVCSDLDTLLLVKELYEQTLIYARYGAKAAGK
>NC_010803.1|WP_012465893.1|1024123_1024927_+|hypothetical-protein
MTWQKYELVFRMLAPLHIGYRTAGNLMQTRSYVPGRVLWAALTTRLTRDEENGTDGLRYIEIGQQVQDHFRFTYLYPATQNGNGYKTYYPWEKDFDYLFLNSYASTSLNYASQSAEEAMLHETEFIAPHTRTGQSVYLVGNVYTKTNLPTPLENWPKALEKLQLGAERGYGWGRVRTVSCDSQGERFYNEPVAELFDGHITAHLKAEKVSGIVGPVEPLIGWERNNDINRKSNWRLTEEAIICYVPGAKVTVDGNYIIGPNGVCGIN
>NC_010803.1|WP_012465894.1|1024985_1026407_+|hypothetical-protein
MVALHDHFVKLVIPFEYSKEYTDAITAINAAVCWEPNTRVPRDMFLHIKHLISSETSNNSIGVSYVLTAAGRLTCNFPLLKDQAGVLLKKGSGDPELPDFEIKFTVPEVYLFLFETQVGFIILDIKYIESGSLEVVEMANHQLKKIGLSRSFICRDGEKPEKAKKGIGFFDRFFESLKPLVSLVSFFEEQERMLRHLYLFNYLILDHLPESDTEKNNFIVETLFRLRNGFHAHYRPSKKEYDPESNSQVLSFVYNIFWGVSQEGVACVACLTGDSRQTHFLTHIFNYNVENSYFYLYILAMAQRFSLLIIAKKTADIPPEIRGSIEELKNKKEIICAIDALRQDIVLYGLRINYSQVSYNFHYTLFYEKLREVFRLDYQHTELDTEVKNLGALIDIIEQKKRINFELNAAVALLVFAVVSVLSDGLSFFQFMNLFDTHRPLLSLTGLILVVVIVLMLFRYFLKKDVLFNIRKR
>NC_010803.1|WP_150081559.1|1027956_1029167_+|IS3-family-transposase
MSEKQRKSFTAQFKAKVALEAIRGEKTLNEIGREFGIHPNLVGQWKREVQEHAAGLFEAKRGPKPVDPLADPEKLYAEIGRLKVELNWLKKKGRSVPMKARKNWISDKEQLSVSTQCELAGVTRSGYYGQSKSLMPNTEDLELMKLIDEEYTRHPFYGSRRMKQVLLTQGRKVNRKRVQRLMRNLGLAGMAPGPNTSKPHPQHKIYPYLLRGLSITRPNHVWSTDVTYCRLPGGFMYLTAVIDWYSRKVLAWRLSNSLDSSYCVDCLEEAIRKYGTPEIFNTDQGVQYTSDAFTSVLKSHEIRISMDGRGRALDNVFVERLWRNVKQEDLYLKGYETAVEMMRGFAEYFRFYNIERPHQSLGYKTPDEVYESAIGGGARIVDKFSKSVSEGSSEATGPQQEAA
>NC_010803.1|WP_081429877.1|1030822_1031194_+|hypothetical-protein
MIANFRNWLILYFRLQVLQENLCRKYEALHGRPYAADNSTFRFTLDHDYADRKNGKIQKLITIKEGRPDETKVKGLLAPFRLEAPLELMEVGYECGFGERNSQGFGMVKVDEDCGGKSVASSQ
>NC_010803.1|WP_012465898.1|1032704_1033211_+|hypothetical-protein
MPEVFQYPMTYPAWWMDYYYIATWCLGMLFLGTGWALFFRYGKFSYGVDLGCFWKTALLIILTTIALGGPNYYNTRFVGEHGQDGDSIKIAGEELLYLDRKGNEKKFALDDITAVYQEPITYNPPPKIFIVAGKGKVKDSLFVTRNLKGFETFLVSLSTRTGVPVKRP

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Crispr_ID: NC_010803_7

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_010803_7

1402679-1402760

Orphan

Consensus_repeat	Method
AACAATGCAGGCACGGTGATCAATAATT	CRISPRCasFinder

1 spacers

The CRISPR arrays of NC_010803_7

>merge|NC_010803|7|1402679-1402760|CRISPRCasFinder
AACAATGCAGGCACGGTGATCAATAATTACGAACTGACCAACAGCGGCACGTTCAACAATGCAGGCACGGTGATCAATAATT

>NC_010803|7|7|1402679-1402760|CRISPRCasFinder
AACAATGCAGGCACGGTGATCAATAATT	ACGAACTGACCAACAGCGGCACGTTC
AACAATGCAGGCACGGTGATCAATAATT

Protein	Signature genes	Signature genes Name	Protein_function
NC_010803.1\|WP_012466250.1\|1407083_1408130_+\|IS630-family-transposase	unknown	unknown	gnl\|CDD\|315923
NC_010803.1\|WP_012466241.1\|1398082_1398529_-\|hypothetical-protein	unknown	unknown	unknown
NC_010803.1\|WP_041465697.1\|1396688_1397243_+\|hypothetical-protein	unknown	unknown	unknown
NC_010803.1\|WP_012466257.1\|1415410_1415911_-\|cupin-domain-containing-protein	unknown	unknown	gnl\|CDD\|380364
NC_010803.1\|WP_012466254.1\|1411570_1412560_-\|alpha/beta-fold-hydrolase	unknown	unknown	gnl\|CDD\|225176
NC_010803.1\|WP_012466258.1\|1416027_1419699_-\|AAA-family-ATPase	unknown	unknown	gnl\|CDD\|129705
NC_010803.1\|WP_012466246.1\|1400492_1400783_+\|putative-addiction-module-antidote-protein	unknown	unknown	gnl\|CDD\|188241
NC_010803.1\|WP_012466256.1\|1414766_1415315_-\|TlpA-family-protein-disulfide-reductase	unknown	unknown	gnl\|CDD\|239264
NC_010803.1\|WP_012466243.1\|1399307_1399559_-\|type-II-toxin-antitoxin-system-ParD-family-antitoxin	unknown	unknown	gnl\|CDD\|274227
NC_010803.1\|WP_150081608.1\|1412881_1414738_-\|protein-disulfide-reductase-DsbD	unknown	unknown	gnl\|CDD\|234717
NC_010803.1\|WP_041465698.1\|1409916_1410318_+\|hypothetical-protein	unknown	unknown	unknown
NC_010803.1\|WP_012466259.1\|1419862_1421008_-\|NADP-dependent-malic-enzyme	unknown	unknown	gnl\|CDD\|223358
NC_010803.1\|WP_012466251.1\|1408799_1409726_+\|YadA-like-family-protein	unknown	unknown	gnl\|CDD\|377158
NC_010803.1\|WP_012466247.1\|1400924_1401701_-\|IS3-family-transposase	unknown	unknown	gnl\|CDD\|222853
NC_010803.1\|WP_012466253.1\|1410413_1411439_+\|sel1-repeat-family-protein	unknown	unknown	gnl\|CDD\|223861
NC_010803.1\|WP_012466240.1\|1397246_1398086_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|366912
NC_010803.1\|WP_012466244.1\|1399752_1400097_-\|hypothetical-protein	unknown	unknown	unknown
NC_010803.1\|WP_012466245.1\|1400182_1400521_+\|type-II-toxin-antitoxin-system-RelE/ParE-family-toxin	unknown	unknown	gnl\|CDD\|162974
NC_010803.1\|WP_012466242.1\|1398994_1399294_-\|type-II-toxin-antitoxin-system-RelE/ParE-family-toxin	unknown	unknown	gnl\|CDD\|226194
NC_010803.1\|WP_012466248.1\|1401697_1401991_-\|IS3-family-transposase	unknown	unknown	gnl\|CDD\|225511

Protein	Function_ID	Function_description	E-value
NC_010803.1\|WP_012466248.1\|1401697_1401991_-\|IS3-family-transposase	gnl\|CDD\|225511	COG2963, COG2963, Transposase and inactivated derivatives [DNA replication, recombination, and repair].	4.79934e-06
NC_010803.1\|WP_012466257.1\|1415410_1415911_-\|cupin-domain-containing-protein	gnl\|CDD\|380364	cd02236, cupin_CV2614-like, Chromobacterium violaceum CV2614 and related proteins, cupin domain. This family includes mostly bacterial proteins homologous to CV2614, a Chromobacterium violaceum protein of unknown function. Proteins in this family belong to the cupin superfamily with a conserved "jelly roll-like" beta-barrel fold capable of homodimerization.	2.25394e-46
NC_010803.1\|WP_012466254.1\|1411570_1412560_-\|alpha/beta-fold-hydrolase	gnl\|CDD\|225176	COG2267, PldB, Lysophospholipase [Lipid metabolism].	2.33594e-08
NC_010803.1\|WP_012466259.1\|1419862_1421008_-\|NADP-dependent-malic-enzyme	gnl\|CDD\|223358	COG0281, SfcA, Malic enzyme [Energy production and conversion].	8.39107e-169
NC_010803.1\|WP_012466243.1\|1399307_1399559_-\|type-II-toxin-antitoxin-system-ParD-family-antitoxin	gnl\|CDD\|274227	TIGR02606, Antitoxin_ParD, putative addiction module antidote protein, CC2985 family. This bacterial protein family has a very similar seed alignment to that of pfam03693 but is a more stringent model with higher cutoff scores. Proteins that score above the trusted cutoff to this model almost invariably are found adjacent to a ParE family protein (pfam05016), where ParE is the killing partner of an addiction module for plasmid stabilization. Members of this family, therefore, are putative addiction module antidote proteins. Some are encoded on plasmids or in prophage regions, but others appear chromosomal. A genome may contain several identical copies, such as the four in Magnetococcus sp. MC-1. This family is named for one member, CC2985 of Caulobacter crescentus CB15. [Cellular processes, Other, Mobile and extrachromosomal element functions, Plasmid functions].	4.69283e-12
NC_010803.1\|WP_012466256.1\|1414766_1415315_-\|TlpA-family-protein-disulfide-reductase	gnl\|CDD\|239264	cd02966, TlpA_like_family, TlpA-like family; composed of TlpA, ResA, DsbE and similar proteins. TlpA, ResA and DsbE are bacterial protein disulfide reductases with important roles in cytochrome maturation. They are membrane-anchored proteins with a soluble TRX domain containing a CXXC motif located in the periplasm. The TRX domains of this family contain an insert, approximately 25 residues in length, which correspond to an extra alpha helix and a beta strand when compared with TRX. TlpA catalyzes an essential reaction in the biogenesis of cytochrome aa3, while ResA and DsbE are essential proteins in cytochrome c maturation. Also included in this family are proteins containing a TlpA-like TRX domain with domain architectures similar to E. coli DipZ protein, and the N-terminal TRX domain of PilB protein from Neisseria which acts as a disulfide reductase that can recylce methionine sulfoxide reductases.	4.69456e-36
NC_010803.1\|WP_012466246.1\|1400492_1400783_+\|putative-addiction-module-antidote-protein	gnl\|CDD\|188241	TIGR02684, conserved_hypothetical_protein, probable addiction module antidote protein. Members of this strictly bacterial protein family are small, at roughly 100 amino acids. The gene is almost invariably the downstream member of a gene pair. It is a predicted DNA-binding protein from a clade within Pfam helix-turn-helix family pfam01381. These gene pairs, when found on the bacterial chromosome, are located often with prophage regions, but also both in integrated plasmid regions and in housekeeping gene regions. Analysis suggests that the gene pair may serve as an addiction module. [Mobile and extrachromosomal element functions, Other].	4.62045e-35
NC_010803.1\|WP_150081608.1\|1412881_1414738_-\|protein-disulfide-reductase-DsbD	gnl\|CDD\|234717	PRK00293, dipZ, thiol:disulfide interchange protein precursor; Provisional.	0
NC_010803.1\|WP_012466251.1\|1408799_1409726_+\|YadA-like-family-protein	gnl\|CDD\|377158	pfam03895, YadA_anchor, YadA-like membrane anchor domain. This region represents the C-terminal 120 amino acids of a family of surface-exposed bacterial proteins. YadA, an adhesin from Yersinia, was the first member of this family to be characterized. UspA2 from Moraxella was second. The Eib immunoglobulin-binding proteins from E. coli were third, followed by the DsrA proteins of Haemophilus ducreyi and others. These proteins are homologous at their C-terminal and have predicted signal sequences, but they diverge elsewhere. The C-terminal 9 amino acids, consisting of alternating hydrophobic amino acids ending in F or W, comprise a targeting motif for the outer membrane of the Gram negative cell envelope. This region is important for oligomerization.	5.85337e-06
NC_010803.1\|WP_012466253.1\|1410413_1411439_+\|sel1-repeat-family-protein	gnl\|CDD\|223861	COG0790, COG0790, FOG: TPR repeat, SEL1 subfamily [General function prediction only].	4.60406e-42
NC_010803.1\|WP_012466240.1\|1397246_1398086_+\|hypothetical-protein	gnl\|CDD\|366912	pfam02085, Cytochrom_CIII, Class III cytochrome C family.	0.000748048
NC_010803.1\|WP_012466247.1\|1400924_1401701_-\|IS3-family-transposase	gnl\|CDD\|222853	PHA02517, PHA02517, putative transposase OrfB; Reviewed.	2.16374e-37
NC_010803.1\|WP_012466258.1\|1416027_1419699_-\|AAA-family-ATPase	gnl\|CDD\|129705	TIGR00618, Nuclease_SbcCD_subunit_C, exonuclease SbcC. All proteins in this family for which functions are known are part of an exonuclease complex with sbcD homologs. This complex is involved in the initiation of recombination to regulate the levels of palindromic sequences in DNA. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair].	4.77888e-68
NC_010803.1\|WP_012466245.1\|1400182_1400521_+\|type-II-toxin-antitoxin-system-RelE/ParE-family-toxin	gnl\|CDD\|162974	TIGR02683, Uncharacterized_protein_HI_1419, putative addiction module killer protein. Members of this strictly bacterial protein family are small, at roughly 100 amino acids. The gene is almost invariably the upstream member of a gene pair, where the downstream member is a predicted DNA-binding protein from a clade within Pfam helix-turn-helix family pfam01381. These gene pairs, when found on the bacterial chromosome, often are located with prophage regions, but also in both integrated plasmid regions and near housekeeping genes. Analysis suggests that the gene pair may serve as an addiction module.	2.76972e-44
NC_010803.1\|WP_012466250.1\|1407083_1408130_+\|IS630-family-transposase	gnl\|CDD\|315923	pfam13358, DDE_3, DDE superfamily endonuclease. This family of proteins are related to pfam00665 and are probably endonucleases of the DDE superfamily. Transposase proteins are necessary for efficient DNA transposition. This domain is a member of the DDE superfamily, which contain three carboxylate residues that are believed to be responsible for coordinating metal ions needed for catalysis. The catalytic activity of this enzyme involves DNA cleavage at a specific site followed by a strand transfer reaction.	1.88898e-39
NC_010803.1\|WP_012466242.1\|1398994_1399294_-\|type-II-toxin-antitoxin-system-RelE/ParE-family-toxin	gnl\|CDD\|226194	COG3668, ParE, Plasmid stabilization system protein [General function prediction only].	1.40061e-19

>NC_010803.1|WP_012466248.1|1401697_1401991_-|IS3-family-transposase
MSEKQRKSFTAQFKAKVALEAIRGEKTLNEIGREFGIHPNLVGQWKREVQEHAAGLFEAKRGPKPVDPLADPEKLYAEIGRLKVELSWLKKKVDPYL
>NC_010803.1|WP_012466247.1|1400924_1401701_-|IS3-family-transposase
MKARKNWISDKEQLSVSTQCELAGVTRSGYYGQSKSLMPNTEDLELMKLIDEEYTRHPFYGSRRMKQVLLTQGRKVNRKRVQRLMRNLGLAGMAPGPNTSKPHPQHKIYPYLLRGLAITRPNHVWSTDVTYCRLPGGFMYLTAVIDWYSRKVLAWRLSNSLDSSFCVDCLEEAIRKYGTPEIFNTDQGVQYTSDAFTSVLKSHEIRISMDGRGRALDNVFVERLWRNVKQEDLYLKGYETAVEMMRDSCQNRVRIRIC
>NC_010803.1|WP_012466246.1|1400492_1400783_+|putative-addiction-module-antidote-protein
MSKVTVRDFDPANYLDNDEMIVEYLKATAEDPDPEVFLEALGDVARAKGMAEIAKKTGLGRESLYKALRPGAHPRYETIKAVLKAVGVEITFKQVS
>NC_010803.1|WP_012466245.1|1400182_1400521_+|type-II-toxin-antitoxin-system-RelE/ParE-family-toxin
MSETITIKVTADFDHWLKRLKNLQARAKVIARIRSAEKGNFGDCKPVGDGVSEMRIHCRSGYRIYFMQNGLTVYILLVGGTKATQQQDITRAKEIARTIKEGNYEQSDSPGF
>NC_010803.1|WP_012466244.1|1399752_1400097_-|hypothetical-protein
MNQRWHKADVGKCDEWQGLLSQDSLDGFGFAGNDFQQYPCVTVRLTTFLLPVLQSPNIETETKEKFRLRQTQTLPDCFDINFIRDMSDKTLGCLNTCIRERTFNRLCDSSGWNV
>NC_010803.1|WP_012466243.1|1399307_1399559_-|type-II-toxin-antitoxin-system-ParD-family-antitoxin
MAMNINLTPSLEKMVRDKVKSGLYTSASEVMREALRLMAEQDSIRQAKMDLLRQDIRAGIESGTALVWDPEEVKKAGRERNKA
>NC_010803.1|WP_012466242.1|1398994_1399294_-|type-II-toxin-antitoxin-system-RelE/ParE-family-toxin
MPTIRIRPLVFDDLAEIWSYIAEDSPNRAVEFIDSIDGKFHELSQSPRIGRSRNELLPGLCSFPVGRYIIFYLIIPDGIEVVRVLHASRDIDEQLNPKQ
>NC_010803.1|WP_012466241.1|1398082_1398529_-|hypothetical-protein
MTATGRKQLVFFAALWIVAFFLNFFWESLHGLLFVDHPAMEAASYVPMMLEMASYDAVAVLGLYLFVALVFRSLLRENTVSHTALFFLVAIIAAAVGEYAAVQILHAWAYLPSMPTVSGIGLLPLMQLAVTGVASIFVAGKLSSVNAD
>NC_010803.1|WP_012466240.1|1397246_1398086_+|hypothetical-protein
MKPLFVFLLCAIILAALALAFPHVMLNPGQLLKGHEKLKTSCMSCHEPFGGTTSARCISCHKPGDIGIRTVAGERIPADSGKTNVHKAIAGKSCTGCHSDHKGAKATALRTFRHLDLPPEILKKCIDCHRERKPEDEIHRSLSSGCAQCHTTDRWKPATFDHRNFNPSSGKQCISCHKEEKPNDALHKEYLAACGSCHSTSRWKPATFNHDRYFRLDGDHRASCRTCHTDPANYKTYTCYNCHEHSAANIAAEHREEGIYRYDNCMKCHRSGKTGEHED
>NC_010803.1|WP_041465697.1|1396688_1397243_+|hypothetical-protein
MSENRGPLHLLLIAAAISLDYILHAVGLAWIGRYLGVAGTVFLASSFGYSARKKKIVKNGTIRFFLRLHCYAGWIGTLMILVHSGIHFNALLPWMATLCMMTVTASGHVGQYLVRKLREEVNMKKKKNGIDNDRDEDIERQCYWDSVTLKALEKWRTIHMPIVSVLLGLTLLHIATILLFMNWR
>NC_010803.1|WP_012466250.1|1407083_1408130_+|IS630-family-transposase
MEKIDIRQHSDRERALLRKQVVRLRKQGKSNKEVAELLGLSVQTSSRWWQWYQRDGNAMLAVPKRGRKHGEKRHLSVEQEKQIQKMIVDHYPDQLKLPFALWDRQAVRQLIKLQFGFEMPIRTVGEYLSRWGYTPQKPIRKAYEQRPAEVARWMEESYPAIQTQAKAENAEIYWGDETGLSTQGNLVRGYAPAGKTPELRLNARKEHVSMISAISNRGKLRFMLYDDAMNGKRLIEFMKRLVKDAGRKVMLILDNLRVHHCKPVKEWLTKNIDTIEVFYLPAYSPELNPDEYLNNDLKNAVHGNKGGVSRNKETIRKKTVSHLRHLQKSPGKVAKLFNHPKVLYAKAS
>NC_010803.1|WP_012466251.1|1408799_1409726_+|YadA-like-family-protein
MKSSKKNRMSSSSCQKKLGITLLCGLLGISGAITPCEPLLAEISGTVSGGTYVVGPEKVVKNGDTITLSSATISGVTFTGDMTIGNLTATDTQVNGPLDVTGQTTTNGITNTGNIATTTLSTTGNANVGGALTTHGITNTGPLSSADGNASLSVANGGTSLGVTNAGGQLNGITSNTGQTRIAGGDSGQSTVTLDNTGVHMANNGAPSRVTGVANGVNDNDAVNMNQLNTLSKKAYSGIAQVGALASIPEPKSGQCYSIGMGVGAYGGQGAVAFGGKAYVNDNITVGAGLGISSGSPSAMAAGASFSW
>NC_010803.1|WP_041465698.1|1409916_1410318_+|hypothetical-protein
MQRYPENEFYPFVVEFMNRHSLSSLRYVFTNNGTMPYDSIIVYGYAARVFFCRTPELITDTIQVYIVTSPAISILDHDTVAIFRKRFSREPDLFHRILIIAHETDILMLGVVSIESKKVKANTICHVYAFRNG
>NC_010803.1|WP_012466253.1|1410413_1411439_+|sel1-repeat-family-protein
MKRYIIGLLAACMLMQPAGARCEIPLLDNISQLQKEAQQGNAVAQNKLGLLYYTGQGVKRDYVEALRWYRMAAEQQRAWAQVSLGVMYYTGQGVKQDHAEAATWFRKAAEQGLPKGEYYLGVVYEKGQGVKQDHAEAATWFRRAAGQGLAEAQNKLGLMYYSGQGVKQDYVEAATWFRKAAVQEFALAQNSLGVMYYTGQGVKQDHAEAATWFRKAAGHGLSVAENKLGLMYYTGQSVKQDYTEAAGWFRKAAVKGLAEAQLNIGMQYYAGQGVNQDYTEAAGWYRKAAEQGLAEAQYNLGAVYLNGSGITKDEQKAREWYKKACNNGYRPACDDYLKINE
>NC_010803.1|WP_012466254.1|1411570_1412560_-|alpha/beta-fold-hydrolase
MHKLLNAIRRRWLLLLISGIVPATLFFILKPRNLPKLVSYPHPAEGYASAARRAENFGVQGKKLMNPLCRLEMMSHKRKTSRAVILVHGYTSCPQQFHELGKRFFELGDNVLIAPLPHHGLAYRLTEDQARLGAEELAAYADEVVDIARGLGDRVVMIGISAGGVTTAWAAQYRSDIDLAVIISPAFGFKEIPVPLTAAVMNMYSLLPDSWSWWDENLKENVPPAYAYPRYSRRALTEILRLGFVVEQAAGKHPPAAKKIVMVFNPNDGSISNERTLQIVERWKAQQATVDSFTFDASLNLGHDIIDPNQPDQKVDIVYPKLIELCGGE
>NC_010803.1|WP_150081608.1|1412881_1414738_-|protein-disulfide-reductase-DsbD
MLHRTISISGFLLFWLIAFSSNGFGTAFLDPGQAFRLKAELTSSGSVVLDWAIADGYKLYRDQVKVSLEKGDAELRIPGLPAGESVTDPSTKERMEVYHDNLRIEVPVVRAAGEFTLKVVYQGCAEDGVCYPPFTRTVTIDPAKPGVLNVVEDPETGGFGGFAVTEDVPVDSLPAAREKKAGDDFSYSQSLLKSRSLLKIGFFFLIFGLALSFTPCILPMIPILSSIIVGDGCYGRGRSFMLAVAYSLGMALVYTLLGVAAGLAGEGLAGALQQPWVLGMFALLLVVLALSMFDVYQLQIPGIMQSSIAKTCGKLKGGQIAGVFLMGSLSALIVGPCVAAPLAGTLVYISQTRHVVIGGLALFSMAMGMSMPLLLVGLSAGTLLPKAGAWMNGVKYLFGLMLIGVAIWMVSPVIPGPLALLFWGALAMLCAVFLHLFDSLPEQSSIAMKFGKALGIVLLVIGILELAGAAAGGTNPLEPLAPFGSGAGGRTSAEEAGLKFTRIRSYAELDAALASAEKPVMLDFYADWCVSCKELEHFTFNDPAVCKQLETMTLLQVDVTANTPDDIALMKRFGIFGPPAIIFFDASGNEIPGSRVVGFVEAKPFLDHLDLYLTRNLP
>NC_010803.1|WP_012466256.1|1414766_1415315_-|TlpA-family-protein-disulfide-reductase
MQLFRSILIAGALAITMHALPALDAVAKKPVRKTALKTWLAPEFSAKSVQGGAVSSRTLAGKGYIVNFFGSWCPYCRKEIPDMAALQEKYEKKGFTFIGMAYRDNEQSMPDFIREQGINYPVVMADEAILDSFGRHVSGGVRSVPALFAINRDGRLLSVIIGAQTQEEFERIITETMKKPVR
>NC_010803.1|WP_012466257.1|1415410_1415911_-|cupin-domain-containing-protein
MIRDCFVRKTQFPISKVLSAIVISVLLAVFQLPDDSLHAEEYRNVTVRKVLVTGTTSDGKKVRYPRTNDAEVTVLVVDVPPGGSTGWHYHPVPVYAYMLEGELAVEMENGTVNLFRKGDAIIEMVDTAHNGYNPGNEKASLVVFYTGAAGVPNVVKEKTPELEGQR
>NC_010803.1|WP_012466258.1|1416027_1419699_-|AAA-family-ATPase
MKILSLRFKNLNSLAGEWFIDFTAPEYVSDGIFAITGPTGSGKTTILDAISLALYGQTPRLEKVNMSGNEVMSRHTGECFAEVVFEAGSGRYRCHWSQHRARRNPQGLLQAQKHEISDETTGKIIESKLQDTLAAVVECTGMDFLQFTRSMLLAQGGFAAFLQAPPDERSPVLEQITGTEIYSAISIKVHERNRLEQLKLDALREECSGIRLLGEDELAEAVFALKDREEQEDGIAGLKSKSEEALRWLRQITVMKAGLAGMEEEFRELRSREERFYPDRQRLEKAMQASRFEPAYTAVMQLRQLQDRDLLDKTVAERELERSKAVFEERAGEFRVAEKRLLLLKEEETALAGVIRVVRALDLQISAGEERRFQSESALNVLQKRIAASEGQLAEAERELLSERKKMEDAERYLSEHEADGGLATSLSGIEEKVRQCQATETAELDARKVRNDASKRLEKAAIALRELMPATAGARKDFDSCLYLQTELAGQLEGLLEGSSLSELRSETARIQERIRALEILQARLMQLAGFEERILTVRQALRSAEAELKHNSFELDRISLLQRKEEQIVEGLQREAELHGKIRSLEDERRMLQEGLPCPLCGSIHHPFVGEDLPDADMAADALRQGRLSLHERALEITGLRVAAARLETEIRQLHGQRDELRKSIETDLQWCRHSAGTLSIEGEPSVENIDAILDKHRLLSVKLSDRLAAAERIEGAHTAAAQEEKNFQQRLTEALRQQESAGYALKTAETEAARAGESEALAGEKRKTADAVLNLELADYAIAAGDGLSYPDVLRQLHSRLERRQEVELRKDAARQRITVLEGFRSVQQELLKTNREDCLQKETAYAAEGAALAGLQRQREGLFGSKNPDAEEGRAAEVARLAEEVLEEVRSAREVASRRIVTLSERVAMLGASSAERSVMISERQALLEHELSGGGFESLERFLSARLDRHEFERLEKQAGALAARRLELETLKGERLGKLLQEEERALTDSSEEVLCEELERFSASLGTLRSDIAALKIRLQEHERSALLLREKTSALAAQQIECARWSSLNELIGSSDGKKFRNFAQGLTFEIMIGHANRQLAGMTDRYLLVRSAAHPLALDVIDTWQAGEVRSTKNLSGGESFIVSLALALGLSHMSSRNVRVDSLFLDEGFGTLDEESLDTALKTLSGLHQNGKIIGIISHVPALKERIAARIRVHPVSGGRSRLSGPGVIEGNG
>NC_010803.1|WP_012466259.1|1419862_1421008_-|NADP-dependent-malic-enzyme
MSYSKKSLDLHRQSRGKIEIKSKVSLKNKEDMSSAYTPGVAAVCTEIARDKQNSYILTNRGSQVAIVSDGTAILGLGDLGAEAAMPVMEGKSIIFKEFANIDAIPLCINSTDVDEIVMFCKLIEPSFAGINLEDISSPRCFEIFEQLEKALSIPVFHDDQDGTAIVTLAAIINACRVTGRELKDLHVVVNGAGAAGIAIARLLIHARVKEVVLVDTQGSLYDGRQGMNPIKQEIAERSNKLKHQGDLQSAMVGADVFVGVSVGNIVTEAMVAGMNLSPFIFPMANPTPEIMPEEAFKAGACIVGTGRSDLPNQVNNALVFPGLFKGLLQSGIRKVTPEMKIAVADAIAHSIVPTADNLMPTTFDKQVVENIVTALAVFSPN

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Crispr_ID: NC_010803_8

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_010803_8

1554065-1554195

Orphan

Consensus_repeat	Method
CCGACTACCGGATACTGATTCTGCCTACCGCTCACCGCTCACTGCCCACA	CRISPRCasFinder

1 spacers

DEDDh

The CRISPR arrays of NC_010803_8

>merge|NC_010803|8|1554065-1554195|CRISPRCasFinder
CCGACTACCGGATACTGATTCTGCCTACCGCTCACCGCTCACTGCCCACAATCCTCACCCGCCCACATTCTTCACCAACTACCGACTACCGGATACTGATTCTGCCTACCGCTCACCGCTCACTGCCCACA

>NC_010803|8|8|1554065-1554195|CRISPRCasFinder
CCGACTACCGGATACTGATTCTGCCTACCGCTCACCGCTCACTGCCCACA	ATCCTCACCCGCCCACATTCTTCACCAACTA
CCGACTACCGGATACTGATTCTGCCTACCGCTCACCGCTCACTGCCCACA

Protein	Signature genes	Signature genes Name	Protein_function
NC_010803.1\|WP_012466383.1\|1552979_1553855_-\|protease-HtpX	unknown	unknown	gnl\|CDD\|235478
NC_010803.1\|WP_081429882.1\|1555519_1555693_-\|DUF2934-domain-containing-protein	unknown	unknown	gnl\|CDD\|378572
NC_010803.1\|WP_012466384.1\|1554223_1555216_-\|glycoside-hydrolase-family-18-protein	unknown	unknown	gnl\|CDD\|366258
NC_010803.1\|WP_012466386.1\|1556197_1556488_-\|hypothetical-protein	unknown	unknown	unknown
NC_010803.1\|WP_012466376.1\|1547731_1548148_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|226765
NC_010803.1\|WP_012466392.1\|1561915_1563484_+\|transposase	unknown	unknown	gnl\|CDD\|227708
NC_010803.1\|WP_012466375.1\|1546324_1547410_-\|alkene-reductase	unknown	unknown	gnl\|CDD\|239243
NC_010803.1\|WP_012466391.1\|1559985_1560957_+\|KamA-family-radical-SAM-protein	unknown	unknown	gnl\|CDD\|224426
NC_010803.1\|WP_012466381.1\|1551223_1551868_-\|3'-5'-exonuclease	DEDDh	cd06127_DEDDh_CAS-I	gnl\|CDD\|176648
NC_010803.1\|WP_012466388.1\|1558368_1558605_+\|hypothetical-protein	unknown	unknown	unknown
NC_010803.1\|WP_041465714.1\|1558632_1559262_+\|tRNA-(guanine-N7)-methyltransferase	unknown	unknown	gnl\|CDD\|234649
NC_010803.1\|WP_012466378.1\|1549497_1549908_+\|hypothetical-protein	unknown	unknown	unknown
NC_010803.1\|WP_012466379.1\|1549956_1550751_+\|sterol-desaturase-family-protein	unknown	unknown	gnl\|CDD\|225546
NC_010803.1\|WP_012466382.1\|1551960_1552824_-\|hypothetical-protein	unknown	unknown	unknown
NC_010803.1\|WP_012466387.1\|1556774_1557782_-\|radical-SAM-protein	unknown	unknown	gnl\|CDD\|223576
NC_010803.1\|WP_041465954.1\|1548386_1549256_+\|UbiA-family-prenyltransferase	unknown	unknown	gnl\|CDD\|260130
NC_010803.1\|WP_012466374.1\|1545392_1546133_+\|DUF2934-domain-containing-protein	unknown	unknown	gnl\|CDD\|378572
NC_010803.1\|WP_012466380.1\|1550757_1551222_-\|rhodanese-like-domain-containing-protein	unknown	unknown	gnl\|CDD\|366179
NC_010803.1\|WP_012466393.1\|1563524_1563932_-\|type-II-toxin-antitoxin-system-VapC-family-toxin	unknown	unknown	gnl\|CDD\|224404
NC_010803.1\|WP_012466390.1\|1559310_1559718_+\|DUF4143-domain-containing-protein	unknown	unknown	gnl\|CDD\|379306

Protein	Function_ID	Function_description	E-value
NC_010803.1\|WP_012466383.1\|1552979_1553855_-\|protease-HtpX	gnl\|CDD\|235478	PRK05457, PRK05457, protease HtpX.	8.44281e-175
NC_010803.1\|WP_012466384.1\|1554223_1555216_-\|glycoside-hydrolase-family-18-protein	gnl\|CDD\|366258	pfam00704, Glyco_hydro_18, Glycosyl hydrolases family 18.	1.42032e-07
NC_010803.1\|WP_012466391.1\|1559985_1560957_+\|KamA-family-radical-SAM-protein	gnl\|CDD\|224426	COG1509, KamA, Lysine 2,3-aminomutase [Amino acid transport and metabolism].	3.57389e-94
NC_010803.1\|WP_012466376.1\|1547731_1548148_+\|hypothetical-protein	gnl\|CDD\|226765	COG4315, COG4315, Uncharacterized protein conserved in bacteria [Function unknown].	4.46444e-19
NC_010803.1\|WP_012466392.1\|1561915_1563484_+\|transposase	gnl\|CDD\|227708	COG5421, COG5421, Transposase [DNA replication, recombination, and repair].	1.46508e-24
NC_010803.1\|WP_012466375.1\|1546324_1547410_-\|alkene-reductase	gnl\|CDD\|239243	cd02933, OYE_like_FMN, Old yellow enzyme (OYE)-like FMN binding domain. OYE was the first flavin-dependent enzyme identified, however its true physiological role remains elusive to this day. Each monomer of OYE contains FMN as a non-covalently bound cofactor, uses NADPH as a reducing agent with oxygens, quinones, and alpha,beta-unsaturated aldehydes and ketones, and can act as electron acceptors in the catalytic reaction. Members of OYE family include 12-oxophytodienoate reductase, pentaerythritol tetranitrate reductase, morphinone reductase, and related enzymes.	0
NC_010803.1\|WP_012466381.1\|1551223_1551868_-\|3'-5'-exonuclease	gnl\|CDD\|176648	cd06127, DEDDh, DEDDh 3'-5' exonuclease domain family. DEDDh exonucleases, part of the DnaQ-like (or DEDD) exonuclease superfamily, catalyze the excision of nucleoside monophosphates at the DNA or RNA termini in the 3'-5' direction. These proteins contain four invariant acidic residues in three conserved sequence motifs termed ExoI, ExoII and ExoIII. DEDDh exonucleases are classified as such because of the presence of specific Hx(4)D conserved pattern at the ExoIII motif. The four conserved acidic residues are clustered around the active site and serve as ligands for the two metal ions required for catalysis. Most DEDDh exonucleases are the proofreading subunits (epsilon) or domains of bacterial DNA polymerase III, the main replicating enzyme in bacteria, which functions as the chromosomal replicase. Other members include other DNA and RNA exonucleases such as RNase T, Oligoribonuclease, and RNA exonuclease (REX), among others.	9.83978e-53
NC_010803.1\|WP_041465714.1\|1558632_1559262_+\|tRNA-(guanine-N7)-methyltransferase	gnl\|CDD\|234649	PRK00121, trmB, tRNA (guanine-N(7)-)-methyltransferase; Reviewed.	4.59644e-36
NC_010803.1\|WP_081429882.1\|1555519_1555693_-\|DUF2934-domain-containing-protein	gnl\|CDD\|378572	pfam11154, DUF2934, Protein of unknown function (DUF2934). This bacterial family of proteins has no known function.	1.73567e-08
NC_010803.1\|WP_012466387.1\|1556774_1557782_-\|radical-SAM-protein	gnl\|CDD\|223576	COG0502, BioB, Biotin synthase and related enzymes [Coenzyme metabolism].	2.09503e-17
NC_010803.1\|WP_041465954.1\|1548386_1549256_+\|UbiA-family-prenyltransferase	gnl\|CDD\|260130	cd13967, PT_UbiA_5, UbiA family of prenyltransferases (PTases), Unknown subgroup. Many characterized members of the UbiA prenyltransferase family are aromatic prenyltransferases and play an important role in the biosynthesis of heme, chlorophyll, vitamin E, and vitamin K. They contain two copies of a motif similar to the active site DxxD motif of trans-prenyltransferases and are potentially related. Prenyltransferases (PTs) catalyze the regioselective transfer of prenyl moieties onto a wide variety of substrates and play an important role in many biosynthetic pathways. The function of this subgroup is unknown.	6.6456e-23
NC_010803.1\|WP_012466380.1\|1550757_1551222_-\|rhodanese-like-domain-containing-protein	gnl\|CDD\|366179	pfam00581, Rhodanese, Rhodanese-like domain. Rhodanese has an internal duplication. This Pfam represents a single copy of this duplicated domain. The domain is found as a single copy in other proteins, including phosphatases and ubiquitin C-terminal hydrolases.	6.11197e-11
NC_010803.1\|WP_012466374.1\|1545392_1546133_+\|DUF2934-domain-containing-protein	gnl\|CDD\|378572	pfam11154, DUF2934, Protein of unknown function (DUF2934). This bacterial family of proteins has no known function.	2.41394e-06
NC_010803.1\|WP_012466379.1\|1549956_1550751_+\|sterol-desaturase-family-protein	gnl\|CDD\|225546	COG3000, ERG3, Sterol desaturase [Lipid metabolism].	5.31143e-29
NC_010803.1\|WP_012466393.1\|1563524_1563932_-\|type-II-toxin-antitoxin-system-VapC-family-toxin	gnl\|CDD\|224404	COG1487, VapC, Predicted nucleic acid-binding protein, contains PIN domain [General function prediction only].	8.91056e-12
NC_010803.1\|WP_012466390.1\|1559310_1559718_+\|DUF4143-domain-containing-protein	gnl\|CDD\|379306	pfam13635, DUF4143, Domain of unknown function (DUF4143). This domain is almost always found C-terminal to an ATPase core family.	9.36803e-31

>NC_010803.1|WP_012466383.1|1552979_1553855_-|protease-HtpX
MKRVVLFLLTNLAVMLVLSVSARILGVDRFLTSNGLDMGMLLVFAALIGFGGSFISLLMSKTMAKWSTGARVIERPANQDEAWLVDTVRQLSKKAGLQMPEVAIYDGAPNAFATGPSKSRSLVAVSTGLMQSMNKKEVGAVLAHEVAHIQNGDMVTLTLIQGVVNTFVIFLSRLAAYAVDSFLRRDDDESGSPGIGYWISSIAFEIMFGILASVVVMCFSRKREYRADAGAAALMGDRAPMIDALRALGGLEAGRLPKEMAASGIAGGGMMALFSSHPPLESRIAALESAS
>NC_010803.1|WP_012466382.1|1551960_1552824_-|hypothetical-protein
MKSFRPVTGITAFIIVLLTMPLGHAAVILLQHALGRDHVAFAGLLLGLTGTGLLLAGMHASKELTATFLGMFGGLFVWAGWIELGFGYYAKRLGIESVMLNGEIVTRAEYLLMPSSVGFFAVIMLYYLFGVRTGCRFFLWFQRLLRIDKKLEPVRLSRNVAMISFMEFIVLLWGFYMVLLFAYDEQFAGDRHPVTYFVAFGSLLWSFLLFVKLITISRLDYAVRYAIPTVIIFWNFVEILGRWHVFTEIWIDPSQYVIEIVLLSIVLLILMLSVLFGEKGEQMASQE
>NC_010803.1|WP_012466381.1|1551223_1551868_-|3'-5'-exonuclease
MQRTLADSVVVLDFETTGLSPQYGDRAIEIGAVLVEHGEIVDRFQKLMNPGFRISSFIEGYTGITNEMLKGQPCCEEVMAEFSGFIAGRNIVAHNASFDRRFLDFELKRAKRVYEGACCCSLLVSRRIYQDSPNHRLQTLVTHAGIPETGSFHRALADAEMTALLWMSMIDRIRRQYGISAITFDQLSDLSKIDKLYTHRYLTALAEELLRKEE
>NC_010803.1|WP_012466380.1|1550757_1551222_-|rhodanese-like-domain-containing-protein
MFGSDRLLDGAIMMIERTHRTENLATDELAAMLAGPAPPLLFDIRKAEEYGKSHIETAIRIEPDTGPDDFAARYAAIMAGRDTVFYCSVGQRSSELLERVESACGKAGAKSCRNLRGGIFRWYNEGRPVVDASGPTDDIHGFDPIWAMMVARRR
>NC_010803.1|WP_012466379.1|1549956_1550751_+|sterol-desaturase-family-protein
MTETLLSIPDLRTLSYGTTIAGGILLWILEGLFPFFSGQKRRDLHARLNLSMAGLNLLILLPSGILMAFMLDWSRNVWPGIGMLVLHPVAETIAIILGIDLWMYVWHRLNHETAFLWRFHSVHHSDATLDVTTSWRFHYMEILFSELLRLPLFMLMGAGIEHLLLYSLLMTPVIEFHHSNISIPPALDRLARLVIPTPVMHRLHHSRERSEHDSNYGSMLSLWDRLFGSFLLKESLDGLRLGLDQESDPGKQRLSALLRRPFRT
>NC_010803.1|WP_012466378.1|1549497_1549908_+|hypothetical-protein
MHENQNIESVKKMALQFLAEAIGQCPAGLESSTNRDIVFAVLGFQYGAVQSAAYVAGLGEDAAADIAQEVIGRINGMEMATASKFVALMPMLAEKGYPPIGIGSKAIIGFYNAAGEEEKLTRAGSLRELLRQIDEA
>NC_010803.1|WP_041465954.1|1548386_1549256_+|UbiA-family-prenyltransferase
MPNYFFRNKLHLSILSSLGAASWSVYFDIPINGWAILCVFLLTFSIYQDNRLTDEREDATNDPEGLKNALKHETLITYVTFYLLSFVSLVIAFQFGQPAFLTTALVIVIGFLYNHRCFPAFISRRLNGARRLKDIFIVKNLTPPIDWATALVFLPLFFEGQTLSAKAWISWGYMYVCAFFVEVMWDMRDHRGDLLSGIRTIANTLSFSQTKHFLIITSLASGLLLFCLTFTNSLPASTYFLLANNVAVILIASMYNEHKEAFMRKISDMSILLATILFLSFGLLAYYSD
>NC_010803.1|WP_012466376.1|1547731_1548148_+|hypothetical-protein
MLFIFGATMMCIVQHSALAAEPNVKVMQKEGVGSYLADGSGKTLYWFKKDSKNTSNCTGACLEKWPAFVTGRMLTVAQPLKTTDFGSIDRPDGKKQNTFRGYPLYYYVMDQQASDTKGHKLNEVWFVIDPGKFPPVAQ
>NC_010803.1|WP_012466375.1|1546324_1547410_-|alkene-reductase
MSILFTPAKLGPFTLQNHMVMAPMTRSRAPGNIPNLLMAEYYAQRATAGLIITEGTSSSPNGLGYPRIPGIFSQGHIEGWKTITDAVHEKGAKMFLQLMHCGRISHPQNMPSGARVVAPSAVAAAGTMYTDAAGLQPFPVPEAMSGEDILSTVAEYADAARNAVAAGFDGIELHGANGYLIEQFIRPNSNLRTDRYGGDIENRARFLLEVVDAAIGAIGRERVGIRLSPFGVFNDMPLYEGIEDYYSWLARQLDASGLAYIHLVDHSSMGAPVVPDSIKAAYRTGFRGTLMLSGGYDAERAESDLASGRCDLVAFGRPFLANPDLVERLKSGAALNQPDMDTFYTPGPEGYTDYPVLNSSL
>NC_010803.1|WP_012466374.1|1545392_1546133_+|DUF2934-domain-containing-protein
MPNITEREIRTLAYKLWQEQGCPVNNRPEEDWTESEWQLMTETALNETASGQMPGEHSDPALHTPYDPFKIGPRNDYQNKISFGGENGKLRWIDNFRVLGTLDTNILRDFKKCYPRLYGNFLVLFKTGSVTENRGEIEANCFYLNNDDTAIYANESLLDALNGAINPFAPVHRTGPDYPPYISGATNATDVEILIPYKIVNDSGETIWCKSLGYNLATGLWRYDDCQAIKAYTTSDRVVWAMFERK
>NC_010803.1|WP_012466384.1|1554223_1555216_-|glycoside-hydrolase-family-18-protein
MRRRLRPILLLLAIATAAVFAWHAWSSGRFVTEVRHDLRTNGIWIQHGWLGDDKWFDRNRRERSRFRNEARIRELSGFLAGHGVRDVFPHLCPCNSDGRIAPADSLQTERFLDGFSGFRVLPWVGGVLGVHCFPESAVWRKSFVSSVVALLGAHPRLAGIHLNIEPMPGGSEAFLVLLDELRQAVPKGKIISVAAFPPPALFQSSPDVHWDKAYYGQVARRSDQIVPMMYDTSSRSSRLYRYLMRVWSVQVLDWSGSTQVLFGVPAYDDSGAGYHIAETENLRNALSGIHAGLESYRVLPENYAGVAIYCEWEMDRSEWASFSSEFGMSR
>NC_010803.1|WP_081429882.1|1555519_1555693_-|DUF2934-domain-containing-protein
MSNDAIEQDSLTPEQREEQIRLAAYFIWQANGEPEGTAEEDWLRAEEALAEESVEAV
>NC_010803.1|WP_012466386.1|1556197_1556488_-|hypothetical-protein
MTPSMEAAKSDKQPVISAVSSPKSKPASSPKPKPDVTGRPSGVQAGSALRLTPFDAYQRVDSAGSGSSNAASAEGRMTTKPVAKKRLTTFFPGGTN
>NC_010803.1|WP_012466387.1|1556774_1557782_-|radical-SAM-protein
MKIDDVLNKTGSGELLSRDEMVFLLDFPSDSIGTYMVMAEANRISKEVSQGKAEVHAQFALNLAPCSCDCLFCSFAEVNGVFTASTALSSDQAVAYARQFEKDGANALFLMSTAHYPFERFLEISGEVRKNLKPETTLIANVGDQSIKSALKLKDAGFSGVYHAVRLREGIDTTLDVGRRRQSIANFREAGLEVGTCVEPVGPEHTNEELADMIAFTASFNPAYSGAARRIPIPGTRLAALGIISELRMAQIVAVTRLGMPRSVLGNCTHEPCTLGAIAGANLFWAEVGANPRDVEAKTEEGRGESVISCRSVFQESNWEVLRGPSRFYNRASSR
>NC_010803.1|WP_012466388.1|1558368_1558605_+|hypothetical-protein
MQTIFADGVANMSLIDGVVRIDLVNVTSIEKDKDPDIQLAGRLAFSLPALIRTHDQLTKMIDKMVADGILTRNAPPSN
>NC_010803.1|WP_041465714.1|1558632_1559262_+|tRNA-(guanine-N7)-methyltransferase
MFMDTRESWCENPVIIADREAWEEINLKEAGTIEVEIGFGSGEYLIRRASEYPDRLFIGIEKKPGMITEVAKMVVSRNLNNIRLLESCAKDAFTDLFPACSISRAYSLFPDPWPKRKHSKYRLFSAQYLRLLNNRLIFGCEALIVTDSEDYCNWMLKQLPETGFEVENSTIPPQFDTRFERRWLEQDLSTFFRILLKKVRHIETLTPPA
>NC_010803.1|WP_012466390.1|1559310_1559718_+|DUF4143-domain-containing-protein
MTTLLPLCHPALHAQNMLQSDWFSGYTATYIERDLRQVIKIQDLSVCQRFVRLCAGRNGQLLNLDALAGETGISHTTARAWLSVLESSYIVHLLPPYYGNFGKRLVKTPKLYCIHQGLTCWLPGIRSIELLADCG
>NC_010803.1|WP_012466391.1|1559985_1560957_+|KamA-family-radical-SAM-protein
MNERRLKHDLITTQEQLAEYVTLTDAEKEGICRCRPIMPMKITRHYAELLDRDNPDDPLRKLAIPSVEELVRYPDDEAVDIHRDEAKYQPVEGIIHRYPGKVLLMYTTACFSHCRFCFRSEKVASTLDGRRLDKAIEYLRKNESIRDVIFTGGDPMHGNPERLEHALYEVRSIPHVEIIRITTRAPIFAPEIFTDELIRMLSWFKPLIMITSFIHPRELSDEVCSVLDRLSDAGIMLLQQGPILKGINDDVDTLRTLYEKLVQHRTMPYYATWGIVSPGNRHFTLDGESARKLIRQLENTTSGFCIPHLSTLDQNNNKTRSIG
>NC_010803.1|WP_012466392.1|1561915_1563484_+|transposase
MAYRVHQLNKKTGVTYVYEAVSTWDKTLKQARNKQICVGKIDPVTGEFVPSKRLDPAQSALRDPAVTASAQVMGPTFVLDAIALRTGVSALMKSVFPQSHQELMAMAFYLTSQGGALSLCASWAKGHMPDLAASLGSQRMSDLLASIGTDRKQAFFAKWMKMRLENDYLCYDITSVSSYSELNEYIKYGYNRDEEKLPQLNLAMLFGQKSGLPGYYHRIPGNINDVSTLHNLLETFRMLEIGQLHYVMDKGFYSKKNVDDLVGYRDHFTISVPINNRWLQRAIDDIHQTIHGPEGYRRLDDEILYVHSRFYPWGEARRRCYLHLYYNATKRAREIDTFNESLFRYREELESGKPIAAHRKAYEDFFTVKTTPKRGTIVSFNTEAINRHISRYAGFQALLSSDIKDPVEALRVYRNKDSVEKCFDDLKNTLDMKRLRMHSSATVDGRLFIQFIALILISALRKQMRDSGLIEQYTVRELLREMETLTKITYSGKYGHILTELTKPQRQILTALNIPVLDPASL
>NC_010803.1|WP_012466393.1|1563524_1563932_-|type-II-toxin-antitoxin-system-VapC-family-toxin
MNGLLVDSNIILDVFLDDPVWADWSEAVLSEYATHSPLCINQIIYSEISIGFKKIEELEAAISSSGLTMLEIPKEALFLAGKAFLSYRKRKGEKRSPLPDFFIGAHAAVSGLELITRDKNRYRTYFPTVRIISPE

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Crispr_ID: NC_010803_9

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_010803_9

1558099-1558221

Orphan

Consensus_repeat	Method
ACTGATTCTGCCCACCACCCACGGCTAACCGCTCACAATCTTC	CRISPRCasFinder

1 spacers

DEDDh

The CRISPR arrays of NC_010803_9

>merge|NC_010803|9|1558099-1558221|CRISPRCasFinder
ACTGATTCTGCCCACCACCCACGGCTAACCGCTCACAATCTTCCCCCCACTCTCCAACAACCGGCTACCGCCTACCGGACACTGATTCTGCCCACCACCCACGGCTAACCGCTCACAATCTTC

>NC_010803|9|9|1558099-1558221|CRISPRCasFinder
ACTGATTCTGCCCACCACCCACGGCTAACCGCTCACAATCTTC	CCCCCACTCTCCAACAACCGGCTACCGCCTACCGGAC
ACTGATTCTGCCCACCACCCACGGCTAACCGCTCACAATCTTC

Protein	Signature genes	Signature genes Name	Protein_function
NC_010803.1\|WP_012466383.1\|1552979_1553855_-\|protease-HtpX	unknown	unknown	gnl\|CDD\|235478
NC_010803.1\|WP_012466382.1\|1551960_1552824_-\|hypothetical-protein	unknown	unknown	unknown
NC_010803.1\|WP_012466384.1\|1554223_1555216_-\|glycoside-hydrolase-family-18-protein	unknown	unknown	gnl\|CDD\|366258
NC_010803.1\|WP_012466386.1\|1556197_1556488_-\|hypothetical-protein	unknown	unknown	unknown
NC_010803.1\|WP_012466392.1\|1561915_1563484_+\|transposase	unknown	unknown	gnl\|CDD\|227708
NC_010803.1\|WP_012466391.1\|1559985_1560957_+\|KamA-family-radical-SAM-protein	unknown	unknown	gnl\|CDD\|224426
NC_010803.1\|WP_012466381.1\|1551223_1551868_-\|3'-5'-exonuclease	DEDDh	cd06127_DEDDh_CAS-I	gnl\|CDD\|176648
NC_010803.1\|WP_012466388.1\|1558368_1558605_+\|hypothetical-protein	unknown	unknown	unknown
NC_010803.1\|WP_041465714.1\|1558632_1559262_+\|tRNA-(guanine-N7)-methyltransferase	unknown	unknown	gnl\|CDD\|234649
NC_010803.1\|WP_012466378.1\|1549497_1549908_+\|hypothetical-protein	unknown	unknown	unknown
NC_010803.1\|WP_012466396.1\|1564993_1565644_-\|TIGR02646-family-protein	unknown	unknown	gnl\|CDD\|131694
NC_010803.1\|WP_081429882.1\|1555519_1555693_-\|DUF2934-domain-containing-protein	unknown	unknown	gnl\|CDD\|378572
NC_010803.1\|WP_041465957.1\|1565640_1566909_-\|AAA-family-ATPase	unknown	unknown	gnl\|CDD\|226459
NC_010803.1\|WP_012466387.1\|1556774_1557782_-\|radical-SAM-protein	unknown	unknown	gnl\|CDD\|223576
NC_010803.1\|WP_012466380.1\|1550757_1551222_-\|rhodanese-like-domain-containing-protein	unknown	unknown	gnl\|CDD\|366179
NC_010803.1\|WP_012466394.1\|1563928_1564153_-\|AbrB/MazE/SpoVT-family-DNA-binding-domain-containing-protein	unknown	unknown	gnl\|CDD\|198034
NC_010803.1\|WP_012466379.1\|1549956_1550751_+\|sterol-desaturase-family-protein	unknown	unknown	gnl\|CDD\|225546
NC_010803.1\|WP_012466393.1\|1563524_1563932_-\|type-II-toxin-antitoxin-system-VapC-family-toxin	unknown	unknown	gnl\|CDD\|224404
NC_010803.1\|WP_041465715.1\|1564167_1564359_-\|hypothetical-protein	unknown	unknown	unknown
NC_010803.1\|WP_012466390.1\|1559310_1559718_+\|DUF4143-domain-containing-protein	unknown	unknown	gnl\|CDD\|379306

Protein	Function_ID	Function_description	E-value
NC_010803.1\|WP_012466383.1\|1552979_1553855_-\|protease-HtpX	gnl\|CDD\|235478	PRK05457, PRK05457, protease HtpX.	8.44281e-175
NC_010803.1\|WP_012466384.1\|1554223_1555216_-\|glycoside-hydrolase-family-18-protein	gnl\|CDD\|366258	pfam00704, Glyco_hydro_18, Glycosyl hydrolases family 18.	1.42032e-07
NC_010803.1\|WP_012466391.1\|1559985_1560957_+\|KamA-family-radical-SAM-protein	gnl\|CDD\|224426	COG1509, KamA, Lysine 2,3-aminomutase [Amino acid transport and metabolism].	3.57389e-94
NC_010803.1\|WP_012466392.1\|1561915_1563484_+\|transposase	gnl\|CDD\|227708	COG5421, COG5421, Transposase [DNA replication, recombination, and repair].	1.46508e-24
NC_010803.1\|WP_012466381.1\|1551223_1551868_-\|3'-5'-exonuclease	gnl\|CDD\|176648	cd06127, DEDDh, DEDDh 3'-5' exonuclease domain family. DEDDh exonucleases, part of the DnaQ-like (or DEDD) exonuclease superfamily, catalyze the excision of nucleoside monophosphates at the DNA or RNA termini in the 3'-5' direction. These proteins contain four invariant acidic residues in three conserved sequence motifs termed ExoI, ExoII and ExoIII. DEDDh exonucleases are classified as such because of the presence of specific Hx(4)D conserved pattern at the ExoIII motif. The four conserved acidic residues are clustered around the active site and serve as ligands for the two metal ions required for catalysis. Most DEDDh exonucleases are the proofreading subunits (epsilon) or domains of bacterial DNA polymerase III, the main replicating enzyme in bacteria, which functions as the chromosomal replicase. Other members include other DNA and RNA exonucleases such as RNase T, Oligoribonuclease, and RNA exonuclease (REX), among others.	9.83978e-53
NC_010803.1\|WP_012466394.1\|1563928_1564153_-\|AbrB/MazE/SpoVT-family-DNA-binding-domain-containing-protein	gnl\|CDD\|198034	smart00966, SpoVT_AbrB, SpoVT / AbrB like domain. This domain is found in AbrB from Bacillus subtilis. The product of the abrB gene is an ambiactive repressor and activator of the transcription of genes expressed during the transition state between vegetative growth and the onset of stationary phase and sporulation. AbrB is thought to interact directly with the transcription initiation regions of genes under its control. AbrB contains a helix-turn-helix structure, but this domain ends before the helix-turn-helix begins. The product of the B. subtilis gene spoVT is another member of this family and is also a transcriptional regulator. DNA-binding activity in this AbrB homologue requires hexamerisation. Another family member has been isolated from the Sulfolobus solfataricus and has been identified as a homologue of bacterial repressor-like proteins. The Escherichia coli family member SohA or Prl1F appears to be bifunctional and is able to regulate its own expression as well as relieve the export block imposed by high-level synthesis of beta-galactosidase hybrid proteins.	2.00037e-08
NC_010803.1\|WP_041465714.1\|1558632_1559262_+\|tRNA-(guanine-N7)-methyltransferase	gnl\|CDD\|234649	PRK00121, trmB, tRNA (guanine-N(7)-)-methyltransferase; Reviewed.	4.59644e-36
NC_010803.1\|WP_012466396.1\|1564993_1565644_-\|TIGR02646-family-protein	gnl\|CDD\|131694	TIGR02646, Hypothetical_protein_SMc04429, TIGR02646 family protein. Members of this uncharacterized protein family are found exclusively in bacteria. Neighboring genes in various genomes are also uncharacterized or may annotated as similar to restriction system proteins. [Hypothetical proteins, Conserved].	2.28033e-11
NC_010803.1\|WP_081429882.1\|1555519_1555693_-\|DUF2934-domain-containing-protein	gnl\|CDD\|378572	pfam11154, DUF2934, Protein of unknown function (DUF2934). This bacterial family of proteins has no known function.	1.73567e-08
NC_010803.1\|WP_012466387.1\|1556774_1557782_-\|radical-SAM-protein	gnl\|CDD\|223576	COG0502, BioB, Biotin synthase and related enzymes [Coenzyme metabolism].	2.09503e-17
NC_010803.1\|WP_012466380.1\|1550757_1551222_-\|rhodanese-like-domain-containing-protein	gnl\|CDD\|366179	pfam00581, Rhodanese, Rhodanese-like domain. Rhodanese has an internal duplication. This Pfam represents a single copy of this duplicated domain. The domain is found as a single copy in other proteins, including phosphatases and ubiquitin C-terminal hydrolases.	6.11197e-11
NC_010803.1\|WP_041465957.1\|1565640_1566909_-\|AAA-family-ATPase	gnl\|CDD\|226459	COG3950, COG3950, Predicted ATP-binding protein involved in virulence [General function prediction only].	1.25961e-45
NC_010803.1\|WP_012466379.1\|1549956_1550751_+\|sterol-desaturase-family-protein	gnl\|CDD\|225546	COG3000, ERG3, Sterol desaturase [Lipid metabolism].	5.31143e-29
NC_010803.1\|WP_012466393.1\|1563524_1563932_-\|type-II-toxin-antitoxin-system-VapC-family-toxin	gnl\|CDD\|224404	COG1487, VapC, Predicted nucleic acid-binding protein, contains PIN domain [General function prediction only].	8.91056e-12
NC_010803.1\|WP_012466390.1\|1559310_1559718_+\|DUF4143-domain-containing-protein	gnl\|CDD\|379306	pfam13635, DUF4143, Domain of unknown function (DUF4143). This domain is almost always found C-terminal to an ATPase core family.	9.36803e-31

>NC_010803.1|WP_012466387.1|1556774_1557782_-|radical-SAM-protein
MKIDDVLNKTGSGELLSRDEMVFLLDFPSDSIGTYMVMAEANRISKEVSQGKAEVHAQFALNLAPCSCDCLFCSFAEVNGVFTASTALSSDQAVAYARQFEKDGANALFLMSTAHYPFERFLEISGEVRKNLKPETTLIANVGDQSIKSALKLKDAGFSGVYHAVRLREGIDTTLDVGRRRQSIANFREAGLEVGTCVEPVGPEHTNEELADMIAFTASFNPAYSGAARRIPIPGTRLAALGIISELRMAQIVAVTRLGMPRSVLGNCTHEPCTLGAIAGANLFWAEVGANPRDVEAKTEEGRGESVISCRSVFQESNWEVLRGPSRFYNRASSR
>NC_010803.1|WP_012466386.1|1556197_1556488_-|hypothetical-protein
MTPSMEAAKSDKQPVISAVSSPKSKPASSPKPKPDVTGRPSGVQAGSALRLTPFDAYQRVDSAGSGSSNAASAEGRMTTKPVAKKRLTTFFPGGTN
>NC_010803.1|WP_081429882.1|1555519_1555693_-|DUF2934-domain-containing-protein
MSNDAIEQDSLTPEQREEQIRLAAYFIWQANGEPEGTAEEDWLRAEEALAEESVEAV
>NC_010803.1|WP_012466384.1|1554223_1555216_-|glycoside-hydrolase-family-18-protein
MRRRLRPILLLLAIATAAVFAWHAWSSGRFVTEVRHDLRTNGIWIQHGWLGDDKWFDRNRRERSRFRNEARIRELSGFLAGHGVRDVFPHLCPCNSDGRIAPADSLQTERFLDGFSGFRVLPWVGGVLGVHCFPESAVWRKSFVSSVVALLGAHPRLAGIHLNIEPMPGGSEAFLVLLDELRQAVPKGKIISVAAFPPPALFQSSPDVHWDKAYYGQVARRSDQIVPMMYDTSSRSSRLYRYLMRVWSVQVLDWSGSTQVLFGVPAYDDSGAGYHIAETENLRNALSGIHAGLESYRVLPENYAGVAIYCEWEMDRSEWASFSSEFGMSR
>NC_010803.1|WP_012466383.1|1552979_1553855_-|protease-HtpX
MKRVVLFLLTNLAVMLVLSVSARILGVDRFLTSNGLDMGMLLVFAALIGFGGSFISLLMSKTMAKWSTGARVIERPANQDEAWLVDTVRQLSKKAGLQMPEVAIYDGAPNAFATGPSKSRSLVAVSTGLMQSMNKKEVGAVLAHEVAHIQNGDMVTLTLIQGVVNTFVIFLSRLAAYAVDSFLRRDDDESGSPGIGYWISSIAFEIMFGILASVVVMCFSRKREYRADAGAAALMGDRAPMIDALRALGGLEAGRLPKEMAASGIAGGGMMALFSSHPPLESRIAALESAS
>NC_010803.1|WP_012466382.1|1551960_1552824_-|hypothetical-protein
MKSFRPVTGITAFIIVLLTMPLGHAAVILLQHALGRDHVAFAGLLLGLTGTGLLLAGMHASKELTATFLGMFGGLFVWAGWIELGFGYYAKRLGIESVMLNGEIVTRAEYLLMPSSVGFFAVIMLYYLFGVRTGCRFFLWFQRLLRIDKKLEPVRLSRNVAMISFMEFIVLLWGFYMVLLFAYDEQFAGDRHPVTYFVAFGSLLWSFLLFVKLITISRLDYAVRYAIPTVIIFWNFVEILGRWHVFTEIWIDPSQYVIEIVLLSIVLLILMLSVLFGEKGEQMASQE
>NC_010803.1|WP_012466381.1|1551223_1551868_-|3'-5'-exonuclease
MQRTLADSVVVLDFETTGLSPQYGDRAIEIGAVLVEHGEIVDRFQKLMNPGFRISSFIEGYTGITNEMLKGQPCCEEVMAEFSGFIAGRNIVAHNASFDRRFLDFELKRAKRVYEGACCCSLLVSRRIYQDSPNHRLQTLVTHAGIPETGSFHRALADAEMTALLWMSMIDRIRRQYGISAITFDQLSDLSKIDKLYTHRYLTALAEELLRKEE
>NC_010803.1|WP_012466380.1|1550757_1551222_-|rhodanese-like-domain-containing-protein
MFGSDRLLDGAIMMIERTHRTENLATDELAAMLAGPAPPLLFDIRKAEEYGKSHIETAIRIEPDTGPDDFAARYAAIMAGRDTVFYCSVGQRSSELLERVESACGKAGAKSCRNLRGGIFRWYNEGRPVVDASGPTDDIHGFDPIWAMMVARRR
>NC_010803.1|WP_012466379.1|1549956_1550751_+|sterol-desaturase-family-protein
MTETLLSIPDLRTLSYGTTIAGGILLWILEGLFPFFSGQKRRDLHARLNLSMAGLNLLILLPSGILMAFMLDWSRNVWPGIGMLVLHPVAETIAIILGIDLWMYVWHRLNHETAFLWRFHSVHHSDATLDVTTSWRFHYMEILFSELLRLPLFMLMGAGIEHLLLYSLLMTPVIEFHHSNISIPPALDRLARLVIPTPVMHRLHHSRERSEHDSNYGSMLSLWDRLFGSFLLKESLDGLRLGLDQESDPGKQRLSALLRRPFRT
>NC_010803.1|WP_012466378.1|1549497_1549908_+|hypothetical-protein
MHENQNIESVKKMALQFLAEAIGQCPAGLESSTNRDIVFAVLGFQYGAVQSAAYVAGLGEDAAADIAQEVIGRINGMEMATASKFVALMPMLAEKGYPPIGIGSKAIIGFYNAAGEEEKLTRAGSLRELLRQIDEA
>NC_010803.1|WP_012466388.1|1558368_1558605_+|hypothetical-protein
MQTIFADGVANMSLIDGVVRIDLVNVTSIEKDKDPDIQLAGRLAFSLPALIRTHDQLTKMIDKMVADGILTRNAPPSN
>NC_010803.1|WP_041465714.1|1558632_1559262_+|tRNA-(guanine-N7)-methyltransferase
MFMDTRESWCENPVIIADREAWEEINLKEAGTIEVEIGFGSGEYLIRRASEYPDRLFIGIEKKPGMITEVAKMVVSRNLNNIRLLESCAKDAFTDLFPACSISRAYSLFPDPWPKRKHSKYRLFSAQYLRLLNNRLIFGCEALIVTDSEDYCNWMLKQLPETGFEVENSTIPPQFDTRFERRWLEQDLSTFFRILLKKVRHIETLTPPA
>NC_010803.1|WP_012466390.1|1559310_1559718_+|DUF4143-domain-containing-protein
MTTLLPLCHPALHAQNMLQSDWFSGYTATYIERDLRQVIKIQDLSVCQRFVRLCAGRNGQLLNLDALAGETGISHTTARAWLSVLESSYIVHLLPPYYGNFGKRLVKTPKLYCIHQGLTCWLPGIRSIELLADCG
>NC_010803.1|WP_012466391.1|1559985_1560957_+|KamA-family-radical-SAM-protein
MNERRLKHDLITTQEQLAEYVTLTDAEKEGICRCRPIMPMKITRHYAELLDRDNPDDPLRKLAIPSVEELVRYPDDEAVDIHRDEAKYQPVEGIIHRYPGKVLLMYTTACFSHCRFCFRSEKVASTLDGRRLDKAIEYLRKNESIRDVIFTGGDPMHGNPERLEHALYEVRSIPHVEIIRITTRAPIFAPEIFTDELIRMLSWFKPLIMITSFIHPRELSDEVCSVLDRLSDAGIMLLQQGPILKGINDDVDTLRTLYEKLVQHRTMPYYATWGIVSPGNRHFTLDGESARKLIRQLENTTSGFCIPHLSTLDQNNNKTRSIG
>NC_010803.1|WP_012466392.1|1561915_1563484_+|transposase
MAYRVHQLNKKTGVTYVYEAVSTWDKTLKQARNKQICVGKIDPVTGEFVPSKRLDPAQSALRDPAVTASAQVMGPTFVLDAIALRTGVSALMKSVFPQSHQELMAMAFYLTSQGGALSLCASWAKGHMPDLAASLGSQRMSDLLASIGTDRKQAFFAKWMKMRLENDYLCYDITSVSSYSELNEYIKYGYNRDEEKLPQLNLAMLFGQKSGLPGYYHRIPGNINDVSTLHNLLETFRMLEIGQLHYVMDKGFYSKKNVDDLVGYRDHFTISVPINNRWLQRAIDDIHQTIHGPEGYRRLDDEILYVHSRFYPWGEARRRCYLHLYYNATKRAREIDTFNESLFRYREELESGKPIAAHRKAYEDFFTVKTTPKRGTIVSFNTEAINRHISRYAGFQALLSSDIKDPVEALRVYRNKDSVEKCFDDLKNTLDMKRLRMHSSATVDGRLFIQFIALILISALRKQMRDSGLIEQYTVRELLREMETLTKITYSGKYGHILTELTKPQRQILTALNIPVLDPASL
>NC_010803.1|WP_012466393.1|1563524_1563932_-|type-II-toxin-antitoxin-system-VapC-family-toxin
MNGLLVDSNIILDVFLDDPVWADWSEAVLSEYATHSPLCINQIIYSEISIGFKKIEELEAAISSSGLTMLEIPKEALFLAGKAFLSYRKRKGEKRSPLPDFFIGAHAAVSGLELITRDKNRYRTYFPTVRIISPE
>NC_010803.1|WP_012466394.1|1563928_1564153_-|AbrB/MazE/SpoVT-family-DNA-binding-domain-containing-protein
MKVTTKGQVTIPVNIREKLGITPDTEVDFLQEGDRIVIVKRKDATTASRKFKKLRGIATVKMTTDEIMALTREV
>NC_010803.1|WP_041465715.1|1564167_1564359_-|hypothetical-protein
MPRGPRLDAQGTLHHLIIRGIERGSIVRDDTDRKTFLDTHGNLSIHEHRLNYQEECGILTGNT
>NC_010803.1|WP_012466396.1|1564993_1565644_-|TIGR02646-family-protein
MIPIAKSTEPQSLQHYRLQKGTVFDGENFTPVKQDIRVQLVAEQGLLCAYCMGRIEPDDRNMKVEHWHSRKRYPAQQLTYANLLGCCCGNEGFPDALAHCDTKKRDDDLLFNPAEPGHHSQLKIRYEFNGTIKSDDALFDRQLNEILNLNYSRLTDNRKSVWSSVTKTLSGITGKATRAQIEGLLLIWQQKNREGKLPEYCGVAQYYFEKKLKRTL
>NC_010803.1|WP_041465957.1|1565640_1566909_-|AAA-family-ATPase
MKIRTLRLINFRGIEELSLPFESGLTVIAAVNGGGKTTVIDALAMLLSWLTARTRRDSGKGRYIKDVEIKNGAKFSLISAQTSSGEWLIAKSRVGTGGISMSNFTALQDIVRHFRHQLESENSLPVFTCYPVDRAVKDTDLPQRIRTRHEFDPISVYDNLLSSGANFRLFFEWFREREDIENENLRANGILNNVDPLEFLDPQLQAVRSALEQFLPEYHDFRIKRQPLRMVVTKGDQELRIDSLSVGETCFIALIGDIARRLAIANPRKQNPLEGEGVVLIDEIDLHLHPAWQRRAVTNLTKVFPNVQFVVTTHSPQILSEVAPESIRLLYQEDNLIKFTIPRQSIGLNSAEILRELMDDPGINSTVPKRIEEIAAKIDHDEFEAAKELIEKLKVDLKGSIPDIVEAEATIAMLEPERGAGE

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Crispr_ID: NC_010803_10

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_010803_10

2065870-2066093

Orphan

Consensus_repeat	Method
CTTCATACCCACTCATCCCTCATCGCTCATCGCTCATCGCCACACTCCCCAATCTTCC	PILER-CR

2 spacers

The CRISPR arrays of NC_010803_10

>merge|NC_010803|10|2065870-2066093|PILER-CR
CTTCATCTCCCCTCATCGCTCATCACTCATCGCCCTCTGGCTCGATAGCTTATTAGCAAGAATAAGAAATACTCCATCTTCCTCCCCCCTCATTGCTCATCGCTCATCGCTCATCGCCACACTCCCCAATCTTCCTGCTAACCGCTAACCACCCACAGCCCACAATCTTCATACCCATTCATCCCTCATCGCTCATCGCTCATCGCCACACTCCCCAATCTTCC

>NC_010803|10|5|2065870-2066093|PILER-CR
CTTCATCTCCCCTCATCGCTCATCACTCATCGCCCTCTGGCTCGATAGCTTATTAGCA	AGAATAAGAAATACTCCATCTTCCTCCCCCCTCATTGCTCATCGCT
CATCGCTCATCGCCACACTCCCCAATCTTCCTGCTAACCGCTAACCACCCACAGCCCA	CAATCTTCATACCCATTCATCCCTCATCGCT
CATCGCTCATCGCCACACTCCCCAATCTTCC

Protein	Signature genes	Signature genes Name	Protein_function
NC_010803.1\|WP_041465748.1\|2051887_2052982_-\|DUF4407-domain-containing-protein	unknown	unknown	gnl\|CDD\|379583
NC_010803.1\|WP_012466780.1\|2058202_2063770_-\|DUF4347-domain-containing-protein	unknown	unknown	gnl\|CDD\|372982
NC_010803.1\|WP_150081894.1\|2043960_2044824_-\|metallophosphoesterase-family-protein	unknown	unknown	gnl\|CDD\|277345
NC_010803.1\|WP_041466011.1\|2066203_2067457_-\|glycosyltransferase-family-4-protein	unknown	unknown	gnl\|CDD\|340845
NC_010803.1\|WP_012466790.1\|2087775_2088447_-\|cyclase-family-protein	unknown	unknown	gnl\|CDD\|224790
NC_010803.1\|WP_012466785.1\|2081918_2082944_-\|metallophosphoesterase	unknown	unknown	unknown
NC_010803.1\|WP_190275071.1\|2057906_2058092_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|369956
NC_010803.1\|WP_012466777.1\|2053635_2054931_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|281416
NC_010803.1\|WP_012466792.1\|2089141_2090425_-\|right-handed-parallel-beta-helix-repeat-containing-protein	unknown	unknown	gnl\|CDD\|378931
NC_010803.1\|WP_012466775.1\|2048140_2048512_-\|four-helix-bundle-protein	unknown	unknown	gnl\|CDD\|183395
NC_010803.1\|WP_190275115.1\|2067538_2068096_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|380205
NC_010803.1\|WP_012466778.1\|2055813_2056725_+\|branched-chain-amino-acid-transaminase	unknown	unknown	gnl\|CDD\|235841
NC_010803.1\|WP_049754361.1\|2088451_2089096_-\|acylneuraminate-cytidylyltransferase-family-protein	unknown	unknown	gnl\|CDD\|133006
NC_010803.1\|WP_012466789.1\|2087014_2087779_-\|2,4-dihydroxyhept-2-ene-1,7-dioic-acid-aldolase	unknown	unknown	gnl\|CDD\|226356
NC_010803.1\|WP_012466788.1\|2085858_2087013_-\|hypothetical-protein	unknown	unknown	unknown
NC_010803.1\|WP_012466781.1\|2064179_2065823_-\|glycosyltransferase-family-4-protein	unknown	unknown	gnl\|CDD\|340831
NC_010803.1\|WP_012466779.1\|2056742_2057915_+\|DNA-polymerase-III-subunit-delta'	unknown	unknown	gnl\|CDD\|379051
NC_010803.1\|WP_012466787.1\|2084610_2085603_-\|NAD-dependent-epimerase/dehydratase-family-protein	unknown	unknown	gnl\|CDD\|187549
NC_010803.1\|WP_012466772.1\|2043354_2043849_+\|ferritin	unknown	unknown	gnl\|CDD\|153113
NC_010803.1\|WP_012466786.1\|2083432_2083780_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|240291

Protein	Function_ID	Function_description	E-value
NC_010803.1\|WP_041465748.1\|2051887_2052982_-\|DUF4407-domain-containing-protein	gnl\|CDD\|379583	pfam14362, DUF4407, Domain of unknown function (DUF4407). This family of proteins is found in bacteria. Proteins in this family are typically between 366 and 597 amino acids in length. There is a single completely conserved residue R that may be functionally important.	1.53621e-98
NC_010803.1\|WP_012466780.1\|2058202_2063770_-\|DUF4347-domain-containing-protein	gnl\|CDD\|372982	pfam14252, DUF4347, Domain of unknown function (DUF4347). This domain family is found in bacteria and eukaryotes, and is approximately 160 amino acids in length. There are two completely conserved residues (C and G) that may be functionally important.	3.76026e-53
NC_010803.1\|WP_150081894.1\|2043960_2044824_-\|metallophosphoesterase-family-protein	gnl\|CDD\|277345	cd07400, MPP_1, Uncharacterized subfamily, metallophosphatase domain. Uncharacterized subfamily of the MPP superfamily. MPPs are functionally diverse, but all share a conserved domain with an active site consisting of two metal ions (usually manganese, iron, or zinc) coordinated with octahedral geometry by a cage of histidine, aspartate, and asparagine residues. The MPP superfamily includes: Mre11/SbcD-like exonucleases, Dbr1-like RNA lariat debranching enzymes, YfcE-like phosphodiesterases, purple acid phosphatases (PAPs), YbbF-like UDP-2,3-diacylglucosamine hydrolases, and acid sphingomyelinases (ASMases). The conserved domain is a double beta-sheet sandwich with a di-metal active site made up of residues located at the C-terminal side of the sheets. This domain is thought to allow for productive metal coordination.	3.7537e-14
NC_010803.1\|WP_041466011.1\|2066203_2067457_-\|glycosyltransferase-family-4-protein	gnl\|CDD\|340845	cd03818, GT4_ExpC-like, Rhizobium meliloti ExpC and similar proteins. This family is most closely related to the GT4 family of glycosyltransferases. ExpC in Rhizobium meliloti has been shown to be involved in the biosynthesis of galactoglucan (exopolysaccharide II).	6.0575e-173
NC_010803.1\|WP_190275071.1\|2057906_2058092_-\|hypothetical-protein	gnl\|CDD\|369956	pfam08564, CDC37_C, Cdc37 C terminal domain. Cdc37 is a protein required for the activity of numerous eukaryotic protein kinases. This domains corresponds to the C terminal domain whose function is unclear. It is found C terminal to the Hsp90 chaperone (Heat shocked protein 90) binding domain pfam08565 and the N terminal kinase binding domain of Cdc37 pfam03234.	0.00421149
NC_010803.1\|WP_012466777.1\|2053635_2054931_-\|hypothetical-protein	gnl\|CDD\|281416	pfam03415, Peptidase_C11, Clostripain family.	1.01605e-18
NC_010803.1\|WP_012466792.1\|2089141_2090425_-\|right-handed-parallel-beta-helix-repeat-containing-protein	gnl\|CDD\|378931	pfam12708, Pectate_lyase_3, Pectate lyase superfamily protein. This family of proteins possesses a beta helical structure like Pectate lyase. This family is most closely related to glycosyl hydrolase family 28.	5.21861e-10
NC_010803.1\|WP_012466775.1\|2048140_2048512_-\|four-helix-bundle-protein	gnl\|CDD\|183395	PRK12275, PRK12275, hypothetical protein; Reviewed.	1.66951e-39
NC_010803.1\|WP_190275115.1\|2067538_2068096_-\|hypothetical-protein	gnl\|CDD\|380205	NF033203, entero_EhxA, enterohemolysin EhxA. Members of this family are the RTX toxin called enterohemolysin or EhxA, because it is found in enterohemorrhagic Escherichia coli (EHEC) strains such as O157:H7.	2.67448e-10
NC_010803.1\|WP_012466778.1\|2055813_2056725_+\|branched-chain-amino-acid-transaminase	gnl\|CDD\|235841	PRK06606, PRK06606, branched-chain amino acid transaminase.	0
NC_010803.1\|WP_049754361.1\|2088451_2089096_-\|acylneuraminate-cytidylyltransferase-family-protein	gnl\|CDD\|133006	cd02513, CMP-NeuAc_Synthase, CMP-NeuAc_Synthase activates N-acetylneuraminic acid by adding CMP moiety. CMP-N-acetylneuraminic acid synthetase (CMP-NeuAc synthetase) or acylneuraminate cytidylyltransferase catalyzes the transfer the CMP moiety of CTP to the anomeric hydroxyl group of NeuAc in the presence of Mg++. It is the second to last step in the sialylation of the oligosaccharide component of glycoconjugates by providing the activated sugar-nucleotide cytidine 5'-monophosphate N-acetylneuraminic acid (CMP-Neu5Ac), the substrate for sialyltransferases. Eukaryotic CMP-NeuAc synthetases are predominantly located in the nucleus. The activated CMP-Neu5Ac diffuses from the nucleus into the cytoplasm.	2.01937e-63
NC_010803.1\|WP_012466789.1\|2087014_2087779_-\|2,4-dihydroxyhept-2-ene-1,7-dioic-acid-aldolase	gnl\|CDD\|226356	COG3836, HpcH, 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase [Carbohydrate transport and metabolism].	1.57493e-56
NC_010803.1\|WP_012466790.1\|2087775_2088447_-\|cyclase-family-protein	gnl\|CDD\|224790	COG1878, COG1878, Kynurenine formamidase [Amino acid transport and metabolism].	2.86041e-26
NC_010803.1\|WP_012466781.1\|2064179_2065823_-\|glycosyltransferase-family-4-protein	gnl\|CDD\|340831	cd03801, GT4_PimA-like, phosphatidyl-myo-inositol mannosyltransferase. This family is most closely related to the GT4 family of glycosyltransferases and named after PimA in Propionibacterium freudenreichii, which is involved in the biosynthesis of phosphatidyl-myo-inositol mannosides (PIM) which are early precursors in the biosynthesis of lipomannans (LM) and lipoarabinomannans (LAM), and catalyzes the addition of a mannosyl residue from GDP-D-mannose (GDP-Man) to the position 2 of the carrier lipid phosphatidyl-myo-inositol (PI) to generate a phosphatidyl-myo-inositol bearing an alpha-1,2-linked mannose residue (PIM1). Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate residue. This group of glycosyltransferases is most closely related to the previously defined glycosyltransferase family 1 (GT1). The members of this family may transfer UDP, ADP, GDP, or CMP linked sugars. The diverse enzymatic activities among members of this family reflect a wide range of biological functions. The protein structure available for this family has the GTB topology, one of the two protein topologies observed for nucleotide-sugar-dependent glycosyltransferases. GTB proteins have distinct N- and C- terminal domains each containing a typical Rossmann fold. The two domains have high structural homology despite minimal sequence homology. The large cleft that separates the two domains includes the catalytic center and permits a high degree of flexibility. The members of this family are found mainly in certain bacteria and archaea.	1.36018e-25
NC_010803.1\|WP_012466779.1\|2056742_2057915_+\|DNA-polymerase-III-subunit-delta'	gnl\|CDD\|379051	pfam13177, DNA_pol3_delta2, DNA polymerase III, delta subunit. DNA polymerase III, delta subunit (EC 2.7.7.7) is required for, along with delta' subunit, the assembly of the processivity factor beta(2) onto primed DNA in the DNA polymerase III holoenzyme-catalyzed reaction. The delta subunit is also known as HolA.	1.0563e-58
NC_010803.1\|WP_012466787.1\|2084610_2085603_-\|NAD-dependent-epimerase/dehydratase-family-protein	gnl\|CDD\|187549	cd05238, Gne_like_SDR_e, Escherichia coli Gne (a nucleoside-diphosphate-sugar 4-epimerase)-like, extended (e) SDRs. Nucleoside-diphosphate-sugar 4-epimerase has the characteristic active site tetrad and NAD-binding motif of the extended SDR, and is related to more specifically defined epimerases such as UDP-glucose 4 epimerase (aka UDP-galactose-4-epimerase), which catalyzes the NAD-dependent conversion of UDP-galactose to UDP-glucose, the final step in Leloir galactose synthesis. This subgroup includes Escherichia coli 055:H7 Gne, a UDP-GlcNAc 4-epimerase, essential for O55 antigen synthesis. Extended SDRs are distinct from classical SDRs. In addition to the Rossmann fold (alpha/beta folding pattern with a central beta-sheet) core region typical of all SDRs, extended SDRs have a less conserved C-terminal extension of approximately 100 amino acids. Extended SDRs are a diverse collection of proteins, and include isomerases, epimerases, oxidoreductases, and lyases; they typically have a TGXXGXXG cofactor binding motif. SDRs are a functionally diverse family of oxidoreductases that have a single domain with a structurally conserved Rossmann fold, an NAD(P)(H)-binding region, and a structurally diverse C-terminal region. Sequence identity between different SDR enzymes is typically in the 15-30% range; they catalyze a wide range of activities including the metabolism of steroids, cofactors, carbohydrates, lipids, aromatic compounds, and amino acids, and act in redox sensing. Classical SDRs have an TGXXX[AG]XG cofactor binding motif and a YXXXK active site motif, with the Tyr residue of the active site motif serving as a critical catalytic residue (Tyr-151, human 15-hydroxyprostaglandin dehydrogenase numbering). In addition to the Tyr and Lys, there is often an upstream Ser and/or an Asn, contributing to the active site; while substrate binding is in the C-terminal region, which determines specificity. The standard reaction mechanism is a 4-pro-S hydride transfer and proton relay involving the conserved Tyr and Lys, a water molecule stabilized by Asn, and nicotinamide. Atypical SDRs generally lack the catalytic residues characteristic of the SDRs, and their glycine-rich NAD(P)-binding motif is often different from the forms normally seen in classical or extended SDRs. Complex (multidomain) SDRs such as ketoreductase domains of fatty acid synthase have a GGXGXXG NAD(P)-binding motif and an altered active site motif (YXXXN). Fungal type ketoacyl reductases have a TGXXXGX(1-2)G NAD(P)-binding motif.	3.46239e-69
NC_010803.1\|WP_012466772.1\|2043354_2043849_+\|ferritin	gnl\|CDD\|153113	cd01055, Nonheme_Ferritin, nonheme-containing ferritins. Nonheme Ferritin domain, found in archaea and bacteria, is a member of a broad superfamily of ferritin-like diiron-carboxylate proteins. The ferritin protein shell is composed of 24 protein subunits arranged in 432 symmetry. Each protein subunit, a four-helix bundle with a fifth short terminal helix, contains a dinuclear ferroxidase center (H type). Unique to this group of proteins is a third metal site in the ferroxidase center. Iron storage involves the uptake of iron (II) at the protein shell, its oxidation by molecular oxygen at the ferroxidase centers, and the movement of iron (III) into the cavity for deposition as ferrihydrite.	1.23077e-76
NC_010803.1\|WP_012466786.1\|2083432_2083780_+\|hypothetical-protein	gnl\|CDD\|240291	PTZ00146, PTZ00146, fibrillarin; Provisional.	0.000227851

>NC_010803.1|WP_012466781.1|2064179_2065823_-|glycosyltransferase-family-4-protein
MNSAILFEPDGYVLSGEKLMGRHAAGHAFLRAAVSGRDGLPLLAYTPHRGSFDVFTRLVHAFDPSAETRWISANRLDLLERSGTLYIPGPGLDTQAWLRLRRGITAYSVCGVTHTTASHGAMDSIAGLLEAPVMEWDALICTSEAVRESVRLVLDAGRDYLQWRFGSVRQLTIPKLPVIPLGVHCDDFRFDEAERKAAREALGISDSAVVALFAGRLSFHAKAHPFAMYAALQQVAERSGRELVLVQSGWFANDHIGNAFSSGSELFCPGVRVLCTDGRKPEERRRSWAAADLFISLSDNIQETFGLTPIEAMAAGLPSLVTDWDGYRDTVRDGIDGFRIATRMPEKGCGSFLAEAHESGSMGYDMYCGYACQLVSLDISALVLRLSELCGNPELRFSMGIAARKRAEEVFDWRVIFSRYKELWQELDAVRAAAVGRSGAVPACSPARMDPFTVFQHYSTFSVNRLSAVSLQPGSGMQHYRQRLAHPLFSYAAGLLPKPGEMERFFLFLMARGTCIIGDIAREIGLDESSIIRAVVMLEKMDIVTIS
>NC_010803.1|WP_012466780.1|2058202_2063770_-|DUF4347-domain-containing-protein
MSNSIYFFDSRVTDIETLIEALPSGSSYVILDSDKDGMRQIAAALAGKTGIDSIQLVSYGSSGTVMLGSTVLTASNLAKYRNELASIGSSLSADGDILLYGCNVGEGVAGKVFVDRLASYTGADVAASVNKTGKGGDWVLEVSSGSIEADSSVFAAAGYEYSLDITGTPGNDALTGTSSADTMYGLAGNDTLNGAGGNDSIDGGEGNDSLNGSTGDDTLIGGSGNDTLNGGSGNDSMVGGSGNDIYYVDSLGDGVLEGLDEGTDRVYSSLAAYTLSDNVENLNLQGAAFHGTGNDLDNSIVGNNSSNSLDGGEGNDSLSGSAGDDTLIGGPGLGNDTLNGGSGSDSMVGGSGNDTYYIDSGTDEIVESLDGGTDRVYSSLISYDMEANVENLILQDGDALFGYGNLLDNSITGNDSDNVLYGGDGNDSLNGGDGNDSLNGGNHNDSLNGGNGNDLLDGGEGNDTLIGGTGTGSGDDTLYGYAGNDSLTGYDGDDSLFGGEENDTLSGGNGNDMLDGGMGIDSMVGGAGNDTYYVDHANDRVNETLVVNGTADHVYSSLSAYTLGNNVENLTLIEGAGDINGTGNTLDNVITGNSGNNTLSGGAGNDTLNGGAGIDSMAGGTGNDTYYVNDPGDVVTETSGGGTADHVYASFSYTLTDNSYIENLTLQEGAGDIVGIGNASDNVLTGSNGNNTLDGALGNDTLDGGAGSDYLDGGAGDDWLSDEDAGGGSNTLDGGDGNDTVDAGYGTQSVTGGAGDDILSVYEATGVLDGGDGADVLDGEYGTYTMTGGSGNDDLYGYYFGGTMSGGADDDNMYVGYGSGTVTMTGDGGNDTLEGQNSTAVLSGDLGNDVVDARHGTYTLTGGEGDDEVSADDATGVLEGGSGNDVVDGEYGTYTMTGGTGNDEMYGYYFSGNMSGNEDDDLMYVGYGEGASVTMSGGSGNDTLIGDLGGTYQMAGDAGNDELYGYTGNDTLDGGAGSDSLDGGAGNDWLSDEDAGGGSNTLEGGDGNDTVDAGYGTQSVTGGAGDDILSVYEATGVLDGGDGADVLDGEYGTYTMTGGSGNDDLYGYYFGGTMSGGADDDNMYVGYGSGTVTMTGDGGNDTLEGQNSTAVLSGDAGDDLVDARHGTYTLTGGEGDDEVSADDATGVLEGGSGNDVVDGEYGTYTMTGGTGNDEMYGYYFSGNMSGNEDDDLMYLGYGEGTSVTMSGDSGNDTLIGDLAGTYQMAGDAGNDELYGDTGNDTLDGGAGSDYLDGGAGDDWLSDEDAEGGSNTLDGGDGNDTVDAGYGTQSVTGGAGDDILSVYEATGVLDGGDGADVLDGEYGTYTMTGGSGNDDLYGYYFGGTMSGGADDDNMYVGYGSGTVTMTGDGGNDTLEGQNSTAVLSGDLGNDVVDARHGTYTLTGGEGDDEVSADDATGVLEGGSGNDVVDGEYGTYTMTGGTGNDEMYGYYFSGSMSGNEDNDNMYVGFGEGASVTMSGGSGNDTMLGDLGGTYLMAGDEGNDELYGYTGNDTLDGGAGNDLVAGASGNDLLYGNEGDDSVYGGFGINTLYGGSGNDSVDGGEMQDFAFGEDGDDTIRGLYGNDVIDGGAGNDLLYGGDNYWQNSYDGNDTISGGAGNDTIDGEAGDDFLNGGSGDDNMFGGYGVIWGYNTIEFSGNDTMFGEDGNDILDGGLDNDSLDGGAGNDYLEGGAGDDFLRDLSGNNTLMGGAGNDYLDGGAENDYLDGGEGADTLLGWDGNDVLLFDENDAVIDGGNGIDTLILGTDASYSFSDIVSDVSVLHMEAIDLTANGNHTLSNVTAADVAAYANGIYILGDSGDTLTSTDTWSDTGDQIVNGITFDIYTSGSATVNIQRGITLA
>NC_010803.1|WP_190275071.1|2057906_2058092_-|hypothetical-protein
MKRMKPEEVEEILDFGLWIVDCGLWGGERLLRIALLEDGKRFWIGWRGVLALLCYQAVLLL
>NC_010803.1|WP_012466779.1|2056742_2057915_+|DNA-polymerase-III-subunit-delta'
MSWKTIIGQKQQIRVLQKALETGRLAHAYLFTGPEASGKESVAFELARTLNCRNKNRAPETGSCGTCPDCMQIDSFMHANIEYIFPVEAALLDSGESAKKENKKFSETKERYEALLEEKKLNPYLTPAMERSMGILSEQIVTLQQKALYRPSEGQRKIFIISQADRMNPAAANKILKLLEEPPAHILFILISSRPEAVLPTIRSRCQIVRFQRPGPMELRKWIQENRPDIHEPELGFIVSFSRGNLALAWDLINQGGVTGNIPVIQLRNQALDYLRLVLTPSRLHEALSACESHAKNLSKTELPLFLGALLLFLQDVNHRLIDPEFQTLNNPDIAASIDRFAKNFPTPDFLAISTITEEAIRAIDRNANPLLVLAAWTSEIKNLILAKSQ
>NC_010803.1|WP_012466778.1|2055813_2056725_+|branched-chain-amino-acid-transaminase
MNKSEKIWMNGELINWSDAKIHILSHAIHYGSSIFEGIRCYETAKGSAVLFLDEHIKRLRDSSKIYRIEIPYSEQELREAIIATIKVNAHKSCYVRPIVYRGQGALGVNPARASIEVAIATWEWGTYLGEDVLENGVDVRVSSWNRLSPNTLPSWAKAGGNYLNSQLIKMEALMDDYAEGLALDHNGYVSEGSGENIFVIRNGVIYTPMTAQSILPGFTRYAVIHIARELGYEVHETLIPREALYVADEVFLTGTAAEITPVRSIDKYPVGNEKRGPITEVLQHHYLKIVQTGEDPYNWLTFI
>NC_010803.1|WP_012466777.1|2053635_2054931_-|hypothetical-protein
MIFSHGNPYRGEHGLPDILYLSPDDFTVTISRMNLNAVDHVAKWTILIYMAADCDLAAFMFDDLMEMKVVGSNEDVNICVFFDGPLLTDTFFARLCHGTSLEEDIIQRFTDVPSSNVGILKEIILNTAVLFPAERRVLVLAGHGLGWRGALRDDSTWKRFKERRAIVMPSGDSSVFFRQLDEQRQRALEELKARLNPRDEHHGSAFDIIAMDACNMGNLEALSFYSDHARILVASENQVPASGYPYDRILEELKRNPEQECDAFARYLVNEVKRYYVDSILLCSESDITQVAFDSTGFPALIAHAGELARVLSEYVSTEGIATVKACSGASLLPEEDTDYIDLRLFAKELVQAGVSDAVKQKAMELVAFFDGSGFVVGSATPGGDALPKGLSIYFPPPERFDKGYLDILSHVPEGIRLWAGFIGAYYGKRF
>NC_010803.1|WP_041465748.1|2051887_2052982_-|DUF4407-domain-containing-protein
MGFSQMQRFFWVCSGTPVDMIEKYSTEHSKYLGIGATIVFTALFAGLSGGYALYFVFAGNVFAPLWSVAFGLLWGLAIFNLDRYIVSSINKTSKGMKQFYQASPRFIFAVLIAIVIARPLELKIFDKEIHERLKERYLMDQKAQIGRVQLSFNEKYAQELSQIRKYQAEYDLLSGDVNRLREELKEEVFGSKTNTTSGVPGYGAYAKNKEAVVGAKQLRLEFLASQLADLQAYMNRQKADEGINKQMMLTEDLLDRKAAHAGFADRNWALGELTRSGDNVSRSSAAAVQFITLLFIAFECAPLIVKLLSDAGPSDVEGNETERRIIAQLTNTAFLNRNRIVRQYRFLGAKSGRRYARRYVGQKR
>NC_010803.1|WP_012466775.1|2048140_2048512_-|four-helix-bundle-protein
MRCETLDVWKISARLSADVYKTISPGKDFGFRDQICRSGLSIPSNIAEGMEKESIRERIKFLDIAKGSAAEFITQVYIGNDIDYITSETSQNWIQTAEHVLSMLNKLQQTLKSQLPAKTHHSH
>NC_010803.1|WP_150081894.1|2043960_2044824_-|metallophosphoesterase-family-protein
MHNTVTVAHISDLHLAGRHDRRSLASLDRMLRHFNERKIDHLVITGDLFDTYMPAEWPVMREKLREHDFCSWERTTLIPGNHDLITIEEEMRIYNALNPFPGSRKRALQERLSGFCALFGDLMGGDGEIKKGFPYVKVMRFPRVSLAFVGVNSVWPWHRSDNPLGARGFIDPAEFRALSQPSVAEALRGSFVIGLCHHALRVYGTSSPIDQAFDWTMELINRDEYLAVMQELRTNVIVHGHFHRFQTYAMGGVQIVNGGSFRYGPDRYSEMVIGEDGSFAQRFVTLS
>NC_010803.1|WP_012466772.1|2043354_2043849_+|ferritin
MLSKKLEKALNEQINHEFASSYLYLSMAAYAESENLPGFASWLKLQTKEEMGHAMKLYKFVNERGGKVELMALEQPKNSFKSPAGLFEEVLGHERKITSLINKLYETALEEKDYAAQVMLHWFIEEQVEEEAAASEILETLKIAGEKGHALIMMDRQLARRGQG
>NC_010803.1|WP_041466011.1|2066203_2067457_-|glycosyltransferase-family-4-protein
MNFLFVHQNFPGQFPHVARALAGMPGNRVVAIAEEKNVVQRLPVHPNVVVKTYRQEKGSGRETHHYIRDFESAVRRGQTVARLAIEIRKSGFHPHVVVGHPAWGETLFLKDVFPNARHISYFEFFYRADGGDVGFDPEFPSVFDDRLRIRVKNTTQLLSLEAADAGISPTLWQQSRFPEEFHSKIRVIHEGVDTAFVRPDPDAAVELDGMTLKRCDKVVTFLSRNLEPYRGFHVFMRTLPLIQKACPEARIVIIGGDGVSYGRRLPEGQTYRAMYAAEAGDKVDWSKVHFTGRVPYNRYLSLLQVSSAHIYLTYPFVLSWSMIEAMSLGCALIASATPPVQEVVEQGENGILVDFFDRDGLAAAVADALDNPGAYEPMRQRARETAVERYDLRSKCLPEMLRYLSGEDDCGLYAVSG
>NC_010803.1|WP_190275115.1|2067538_2068096_-|hypothetical-protein
MLDGDSGNDTLYGGEGTDSMKGRAGNDSLDGGFGDDMLDGGAGSDYLDGSYGTDMLYGGDGDDTLVFDRYDAMIDGEDGFDTLVFAGDDNFGFGELLTSGVVGIELIDLTSGSHALTDITSDDVASVLGGGTELFINGDTYDTVGLGSGWTNTGSSEIGGVSYNGYNSDGMNVYVQSGIAVQQES
>NC_010803.1|WP_012466785.1|2081918_2082944_-|metallophosphoesterase
MYTHTALFKKYSGVFLVKKKTILNAYLFAVIILFFPFSGKASVHFLATADPQYDNGNSAVNQQANKTLLTMLASIKCNNDIKGIIVAGDLTQNSRIYDEFSWYNNALSIQNKVTGDVVDMSAYVYDGIGNHDKAEPTFMQKTACFFKTAECVNPEVIQNTLSSRVRLTPVLYREGIHYAWKWDDVVFVQLNLFPGDSNDNYGLSPQNSLTYLRNLLNNRVDKNKDRIVLIHHYGFDPFSQTYWSDSQRKEYWNLIADYNVMGILTGHSHNNTGYTFYNAFTRPSGYTKGPASIASFVCGGACLGYYLDITIDGNTMHVRQRDNNGTQKKAVLVDNGVIYYR
>NC_010803.1|WP_012466786.1|2083432_2083780_+|hypothetical-protein
MQNKTITRILALSIITATFPSYNVSAVPPTASDHSATAASGSIGATVGLAISIGLPKENKNSPGNPGGPGGNPGNQGGPGGNPGNPSGGAGNPGGPGGNPGNPGRGNSGGGNPGR
>NC_010803.1|WP_012466787.1|2084610_2085603_-|NAD-dependent-epimerase/dehydratase-family-protein
MLKRVLLIGASGFVGTRLIETIGEKRCINIDKQNSSRYNNITLIHDIRNDGIDVAISHQPSSIVLLAAEHRDDVSPISLYYDVNVQGTKNVLDAMDHKGIKSIIFTSSVAVYGLNKKISDETHQADPFNHYGKSKWEAEEVLREWYQKDPENRSLSIIRPTVIFGEANRGNVYNLLKQIALGKFLMIGKGENKKSMAYVGNVVVFIKYLIENDKPGYRVYNYVDKPDFNMNELVHQVRHDLGQDGKMIRIPEWLGMLGGYGFDIAAKLSGKKLPISSVRVKKFCATTQFSADKLDKSGFIRPYTIEEGLERTLRYEFLEKNDDKHVFYTE
>NC_010803.1|WP_012466788.1|2085858_2087013_-|hypothetical-protein
MKKYIYFYDLNEKLLARYPAKISQEILSTHQDAEFVYLYSERYEKKGNPDKLPEGSKVVYLPTLSMTKIQKLFKTHPPALFITIGMRLPDILMLSFFNRHQVPTCMVQHGLFIKHLERIPLHLVIGQKLIKFTQYLIYSYKISRVLKKSFLKTLYELYLYFIKGSHKIPQLKHINSSLILAKTAFIFDDNWKKYYFITYGYTEEQFYKIGNPDFLILKQLKSAVQENAVCYICQSLVEDGRYLRSDFMCYIKEIEENLADDIKVYFKMHPRSRMELYEELNTDKINFTQEFPNCKFYLGHYSSLLAVAHDISQVIIWNLKGHQTPAEYVKYADMISNDWEEVRSFIRIKQQDNTTKDFDASYMEDSFNPYYHIAQFINQKATDF
>NC_010803.1|WP_012466789.1|2087014_2087779_-|2,4-dihydroxyhept-2-ene-1,7-dioic-acid-aldolase
MKNTRLKGQLKNNEQTLGSWVTIGHPAVVEVLSNANFDWLTIDIEHNNIDPAMLTTLIATIQSKNIAALVRVSKNEEVPIKHAMDAGADGVIVPMVNSREDAEKAVEYVKYPPRGKRGVGLSRAQNYGIGFESYKQWLQAYSVIIAQIEHIDGVRNIEQIIEVPDIDAIIIGPYDLSGSLGYPGNYSREDVREALIRVEQVCRERNFPMGFHVVPPDVEEVAIRRAAGYSFIAFSTDFLLMGDTATKLVNHLRK
>NC_010803.1|WP_012466790.1|2087775_2088447_-|cyclase-family-protein
MIFLSHHYASDTPTYGDRDKFKVAANSTIAGGGTANSSSWVFTNNHIGTHIDTPYHFNRNGMQTLDYPADFWYFNRVEIIDIPCNAARIIGPEAVAGCIIDPGTEMLLIRTGYELVRQEDKYWNDNPGLAPELADYLRSNFSKMRVIGFDFISITSWKHRQLGRESHKAFLVPGPGRIPILAIEDMALQAVHESIEWALVSPLRTEEGNGCPVTVFAKLTSDS
>NC_010803.1|WP_049754361.1|2088451_2089096_-|acylneuraminate-cytidylyltransferase-family-protein
MKGHSERVPNKNLRPVAGKPCFHWIIESLERSPYIGEIVINTDSDEIAESAKKNFQVTILERPDYLLGDMVSIQPLIEYDLSMTEGDYYLQTHSTNPLVTTETINNSIKTFFNQKEHDALFTVTPIKTRFYRADGSGVNHDPRHLIRTQDLDPIFEENSCLYIFSKKTNEQIRNRLGANPMMYPMDHLEAVDIDDMHDLLWAEFLLNQRLTRKL
>NC_010803.1|WP_012466792.1|2089141_2090425_-|right-handed-parallel-beta-helix-repeat-containing-protein
MKSGLRSIFLILWCGLLPAKNGSAYAAFNTFSRVSDLNSLRQLSEQMVFVLGYSEPGDGGGGWFRWEPNIMEEPDGSMRIRPHSFKQGCFARVTDGAGLNVKWFGAKGDGKHNDTEAIQSAIEWASARQSFFQQSIAVRDLVLIPSGQFLVDSLELKSGVILQGAGQFSSVILHTGNSSRCIYNEKGHHNRWVGIRELTVIGSDNKGTYTEGIHLFEANYSSYINRITIRGFTQNIVLEDCWTFQLTRSHLFKAHRNNLTILNGTAMEISGNRIDGAGKSNIQISRSKRYRNTGILIRNNAIQQAQEYGLYCRDTNSLLLEGNFFEANNRNGGFAFVYIEGPQTSKHCLIHSTSNYFSGANKSAPNSVGIFLKGNVKSFSSNQDYFSGSMGYGIYSVDLQSKEFVISGTTFHSKSDLKLPSDIKIIN

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Crispr_ID: NC_010803_11

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_010803_11

2070863-2071108

Orphan

Consensus_repeat	Method
CATATCCCCGGACAGGGTATCGTTCCCGGCTCCGCCATCCAT	CRISPRCasFinder

2 spacers

The CRISPR arrays of NC_010803_11

>merge|NC_010803|11|2070863-2071108|CRISPRCasFinder
CATATCCCCGGACAGGGTATCGTTCCCGGCTCCGCCATCCATACTGTTACCGTCCAGAGCGGAGAGCGCATCGTCCCCCTCGCCGCCCTGCATCGTGTTGAACATATCCCCGGTCAGGGTATCGTTCCCGGCTCCGCCATCCATGAGCTCCGACATCCAGCCGTCGAGCAGGTCGTCGCCTTCGCCGCCCGACATCGAATCCTCTGAATCGCCGTACAGGGTATCGTTGCCGCTGCCTCCCTCAAG

>NC_010803|11|10|2070863-2071108|CRISPRCasFinder
CATATCCCCGGACAGGGTATCGTTCCCGGCTCCGCCATCCAT	ACTGTTACCGTCCAGAGCGGAGAGCGCATCGTCCCCCTCGCCGCCCTGCATCGTGTTGAA
CATATCCCCGGTCAGGGTATCGTTCCCGGCTCCGCCATCCAT	GAGCTCCGACATCCAGCCGTCGAGCAGGTCGTCGCCTTCGCCGCCCGACATCGAATCCTC
TGAATCGCCGTACAGGGTATCGTTGCCGCTGCCTCCCTCAAG

Protein	Signature genes	Signature genes Name	Protein_function
NC_010803.1\|WP_041465748.1\|2051887_2052982_-\|DUF4407-domain-containing-protein	unknown	unknown	gnl\|CDD\|379583
NC_010803.1\|WP_012466780.1\|2058202_2063770_-\|DUF4347-domain-containing-protein	unknown	unknown	gnl\|CDD\|372982
NC_010803.1\|WP_012466781.1\|2064179_2065823_-\|glycosyltransferase-family-4-protein	unknown	unknown	gnl\|CDD\|340831
NC_010803.1\|WP_012466790.1\|2087775_2088447_-\|cyclase-family-protein	unknown	unknown	gnl\|CDD\|224790
NC_010803.1\|WP_012466785.1\|2081918_2082944_-\|metallophosphoesterase	unknown	unknown	unknown
NC_010803.1\|WP_190275071.1\|2057906_2058092_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|369956
NC_010803.1\|WP_012466777.1\|2053635_2054931_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|281416
NC_010803.1\|WP_150081661.1\|2090887_2091967_-\|3-dehydroquinate-synthase	unknown	unknown	gnl\|CDD\|275218
NC_010803.1\|WP_012466792.1\|2089141_2090425_-\|right-handed-parallel-beta-helix-repeat-containing-protein	unknown	unknown	gnl\|CDD\|378931
NC_010803.1\|WP_012466775.1\|2048140_2048512_-\|four-helix-bundle-protein	unknown	unknown	gnl\|CDD\|183395
NC_010803.1\|WP_190275115.1\|2067538_2068096_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|380205
NC_010803.1\|WP_012466778.1\|2055813_2056725_+\|branched-chain-amino-acid-transaminase	unknown	unknown	gnl\|CDD\|235841
NC_010803.1\|WP_049754361.1\|2088451_2089096_-\|acylneuraminate-cytidylyltransferase-family-protein	unknown	unknown	gnl\|CDD\|133006
NC_010803.1\|WP_012466789.1\|2087014_2087779_-\|2,4-dihydroxyhept-2-ene-1,7-dioic-acid-aldolase	unknown	unknown	gnl\|CDD\|226356
NC_010803.1\|WP_012466788.1\|2085858_2087013_-\|hypothetical-protein	unknown	unknown	unknown
NC_010803.1\|WP_041466011.1\|2066203_2067457_-\|glycosyltransferase-family-4-protein	unknown	unknown	gnl\|CDD\|340845
NC_010803.1\|WP_012466793.1\|2090428_2090881_-\|YhcH/YjgK/YiaL-family-protein	unknown	unknown	gnl\|CDD\|225345
NC_010803.1\|WP_012466779.1\|2056742_2057915_+\|DNA-polymerase-III-subunit-delta'	unknown	unknown	gnl\|CDD\|379051
NC_010803.1\|WP_012466787.1\|2084610_2085603_-\|NAD-dependent-epimerase/dehydratase-family-protein	unknown	unknown	gnl\|CDD\|187549
NC_010803.1\|WP_012466786.1\|2083432_2083780_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|240291

Protein	Function_ID	Function_description	E-value
NC_010803.1\|WP_041465748.1\|2051887_2052982_-\|DUF4407-domain-containing-protein	gnl\|CDD\|379583	pfam14362, DUF4407, Domain of unknown function (DUF4407). This family of proteins is found in bacteria. Proteins in this family are typically between 366 and 597 amino acids in length. There is a single completely conserved residue R that may be functionally important.	1.53621e-98
NC_010803.1\|WP_012466780.1\|2058202_2063770_-\|DUF4347-domain-containing-protein	gnl\|CDD\|372982	pfam14252, DUF4347, Domain of unknown function (DUF4347). This domain family is found in bacteria and eukaryotes, and is approximately 160 amino acids in length. There are two completely conserved residues (C and G) that may be functionally important.	3.76026e-53
NC_010803.1\|WP_012466781.1\|2064179_2065823_-\|glycosyltransferase-family-4-protein	gnl\|CDD\|340831	cd03801, GT4_PimA-like, phosphatidyl-myo-inositol mannosyltransferase. This family is most closely related to the GT4 family of glycosyltransferases and named after PimA in Propionibacterium freudenreichii, which is involved in the biosynthesis of phosphatidyl-myo-inositol mannosides (PIM) which are early precursors in the biosynthesis of lipomannans (LM) and lipoarabinomannans (LAM), and catalyzes the addition of a mannosyl residue from GDP-D-mannose (GDP-Man) to the position 2 of the carrier lipid phosphatidyl-myo-inositol (PI) to generate a phosphatidyl-myo-inositol bearing an alpha-1,2-linked mannose residue (PIM1). Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate residue. This group of glycosyltransferases is most closely related to the previously defined glycosyltransferase family 1 (GT1). The members of this family may transfer UDP, ADP, GDP, or CMP linked sugars. The diverse enzymatic activities among members of this family reflect a wide range of biological functions. The protein structure available for this family has the GTB topology, one of the two protein topologies observed for nucleotide-sugar-dependent glycosyltransferases. GTB proteins have distinct N- and C- terminal domains each containing a typical Rossmann fold. The two domains have high structural homology despite minimal sequence homology. The large cleft that separates the two domains includes the catalytic center and permits a high degree of flexibility. The members of this family are found mainly in certain bacteria and archaea.	1.36018e-25
NC_010803.1\|WP_150081661.1\|2090887_2091967_-\|3-dehydroquinate-synthase	gnl\|CDD\|275218	TIGR04425, 3-dehydroquinate_synthase, putative sugar phosphate phospholyase (cyclizing). Members of this family tend to be found in O-antigen biosynthesis regions. Members frequently are misidentified as the closely related 3-dehydroquinate synthase, AroB (see family TIGR01357), the phospholyase that converts 3-deoxy-D-arabino-hept-2-ulosonate 7-phosphate to 3-dehydroquinate during chorismate biosynthesis. Most bacteria with this enzyme have a true AroB in a chorismate biosynthesis gene cluster. [Biosynthesis of cofactors, prosthetic groups, and carriers, Lipoate].	0
NC_010803.1\|WP_190275071.1\|2057906_2058092_-\|hypothetical-protein	gnl\|CDD\|369956	pfam08564, CDC37_C, Cdc37 C terminal domain. Cdc37 is a protein required for the activity of numerous eukaryotic protein kinases. This domains corresponds to the C terminal domain whose function is unclear. It is found C terminal to the Hsp90 chaperone (Heat shocked protein 90) binding domain pfam08565 and the N terminal kinase binding domain of Cdc37 pfam03234.	0.00421149
NC_010803.1\|WP_012466777.1\|2053635_2054931_-\|hypothetical-protein	gnl\|CDD\|281416	pfam03415, Peptidase_C11, Clostripain family.	1.01605e-18
NC_010803.1\|WP_012466792.1\|2089141_2090425_-\|right-handed-parallel-beta-helix-repeat-containing-protein	gnl\|CDD\|378931	pfam12708, Pectate_lyase_3, Pectate lyase superfamily protein. This family of proteins possesses a beta helical structure like Pectate lyase. This family is most closely related to glycosyl hydrolase family 28.	5.21861e-10
NC_010803.1\|WP_012466775.1\|2048140_2048512_-\|four-helix-bundle-protein	gnl\|CDD\|183395	PRK12275, PRK12275, hypothetical protein; Reviewed.	1.66951e-39
NC_010803.1\|WP_190275115.1\|2067538_2068096_-\|hypothetical-protein	gnl\|CDD\|380205	NF033203, entero_EhxA, enterohemolysin EhxA. Members of this family are the RTX toxin called enterohemolysin or EhxA, because it is found in enterohemorrhagic Escherichia coli (EHEC) strains such as O157:H7.	2.67448e-10
NC_010803.1\|WP_012466778.1\|2055813_2056725_+\|branched-chain-amino-acid-transaminase	gnl\|CDD\|235841	PRK06606, PRK06606, branched-chain amino acid transaminase.	0
NC_010803.1\|WP_049754361.1\|2088451_2089096_-\|acylneuraminate-cytidylyltransferase-family-protein	gnl\|CDD\|133006	cd02513, CMP-NeuAc_Synthase, CMP-NeuAc_Synthase activates N-acetylneuraminic acid by adding CMP moiety. CMP-N-acetylneuraminic acid synthetase (CMP-NeuAc synthetase) or acylneuraminate cytidylyltransferase catalyzes the transfer the CMP moiety of CTP to the anomeric hydroxyl group of NeuAc in the presence of Mg++. It is the second to last step in the sialylation of the oligosaccharide component of glycoconjugates by providing the activated sugar-nucleotide cytidine 5'-monophosphate N-acetylneuraminic acid (CMP-Neu5Ac), the substrate for sialyltransferases. Eukaryotic CMP-NeuAc synthetases are predominantly located in the nucleus. The activated CMP-Neu5Ac diffuses from the nucleus into the cytoplasm.	2.01937e-63
NC_010803.1\|WP_012466789.1\|2087014_2087779_-\|2,4-dihydroxyhept-2-ene-1,7-dioic-acid-aldolase	gnl\|CDD\|226356	COG3836, HpcH, 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase [Carbohydrate transport and metabolism].	1.57493e-56
NC_010803.1\|WP_012466790.1\|2087775_2088447_-\|cyclase-family-protein	gnl\|CDD\|224790	COG1878, COG1878, Kynurenine formamidase [Amino acid transport and metabolism].	2.86041e-26
NC_010803.1\|WP_041466011.1\|2066203_2067457_-\|glycosyltransferase-family-4-protein	gnl\|CDD\|340845	cd03818, GT4_ExpC-like, Rhizobium meliloti ExpC and similar proteins. This family is most closely related to the GT4 family of glycosyltransferases. ExpC in Rhizobium meliloti has been shown to be involved in the biosynthesis of galactoglucan (exopolysaccharide II).	6.0575e-173
NC_010803.1\|WP_012466793.1\|2090428_2090881_-\|YhcH/YjgK/YiaL-family-protein	gnl\|CDD\|225345	COG2731, EbgC, Beta-galactosidase, beta subunit [Carbohydrate transport and metabolism].	2.59014e-26
NC_010803.1\|WP_012466779.1\|2056742_2057915_+\|DNA-polymerase-III-subunit-delta'	gnl\|CDD\|379051	pfam13177, DNA_pol3_delta2, DNA polymerase III, delta subunit. DNA polymerase III, delta subunit (EC 2.7.7.7) is required for, along with delta' subunit, the assembly of the processivity factor beta(2) onto primed DNA in the DNA polymerase III holoenzyme-catalyzed reaction. The delta subunit is also known as HolA.	1.0563e-58
NC_010803.1\|WP_012466787.1\|2084610_2085603_-\|NAD-dependent-epimerase/dehydratase-family-protein	gnl\|CDD\|187549	cd05238, Gne_like_SDR_e, Escherichia coli Gne (a nucleoside-diphosphate-sugar 4-epimerase)-like, extended (e) SDRs. Nucleoside-diphosphate-sugar 4-epimerase has the characteristic active site tetrad and NAD-binding motif of the extended SDR, and is related to more specifically defined epimerases such as UDP-glucose 4 epimerase (aka UDP-galactose-4-epimerase), which catalyzes the NAD-dependent conversion of UDP-galactose to UDP-glucose, the final step in Leloir galactose synthesis. This subgroup includes Escherichia coli 055:H7 Gne, a UDP-GlcNAc 4-epimerase, essential for O55 antigen synthesis. Extended SDRs are distinct from classical SDRs. In addition to the Rossmann fold (alpha/beta folding pattern with a central beta-sheet) core region typical of all SDRs, extended SDRs have a less conserved C-terminal extension of approximately 100 amino acids. Extended SDRs are a diverse collection of proteins, and include isomerases, epimerases, oxidoreductases, and lyases; they typically have a TGXXGXXG cofactor binding motif. SDRs are a functionally diverse family of oxidoreductases that have a single domain with a structurally conserved Rossmann fold, an NAD(P)(H)-binding region, and a structurally diverse C-terminal region. Sequence identity between different SDR enzymes is typically in the 15-30% range; they catalyze a wide range of activities including the metabolism of steroids, cofactors, carbohydrates, lipids, aromatic compounds, and amino acids, and act in redox sensing. Classical SDRs have an TGXXX[AG]XG cofactor binding motif and a YXXXK active site motif, with the Tyr residue of the active site motif serving as a critical catalytic residue (Tyr-151, human 15-hydroxyprostaglandin dehydrogenase numbering). In addition to the Tyr and Lys, there is often an upstream Ser and/or an Asn, contributing to the active site; while substrate binding is in the C-terminal region, which determines specificity. The standard reaction mechanism is a 4-pro-S hydride transfer and proton relay involving the conserved Tyr and Lys, a water molecule stabilized by Asn, and nicotinamide. Atypical SDRs generally lack the catalytic residues characteristic of the SDRs, and their glycine-rich NAD(P)-binding motif is often different from the forms normally seen in classical or extended SDRs. Complex (multidomain) SDRs such as ketoreductase domains of fatty acid synthase have a GGXGXXG NAD(P)-binding motif and an altered active site motif (YXXXN). Fungal type ketoacyl reductases have a TGXXXGX(1-2)G NAD(P)-binding motif.	3.46239e-69
NC_010803.1\|WP_012466786.1\|2083432_2083780_+\|hypothetical-protein	gnl\|CDD\|240291	PTZ00146, PTZ00146, fibrillarin; Provisional.	0.000227851

>NC_010803.1|WP_190275115.1|2067538_2068096_-|hypothetical-protein
MLDGDSGNDTLYGGEGTDSMKGRAGNDSLDGGFGDDMLDGGAGSDYLDGSYGTDMLYGGDGDDTLVFDRYDAMIDGEDGFDTLVFAGDDNFGFGELLTSGVVGIELIDLTSGSHALTDITSDDVASVLGGGTELFINGDTYDTVGLGSGWTNTGSSEIGGVSYNGYNSDGMNVYVQSGIAVQQES
>NC_010803.1|WP_041466011.1|2066203_2067457_-|glycosyltransferase-family-4-protein
MNFLFVHQNFPGQFPHVARALAGMPGNRVVAIAEEKNVVQRLPVHPNVVVKTYRQEKGSGRETHHYIRDFESAVRRGQTVARLAIEIRKSGFHPHVVVGHPAWGETLFLKDVFPNARHISYFEFFYRADGGDVGFDPEFPSVFDDRLRIRVKNTTQLLSLEAADAGISPTLWQQSRFPEEFHSKIRVIHEGVDTAFVRPDPDAAVELDGMTLKRCDKVVTFLSRNLEPYRGFHVFMRTLPLIQKACPEARIVIIGGDGVSYGRRLPEGQTYRAMYAAEAGDKVDWSKVHFTGRVPYNRYLSLLQVSSAHIYLTYPFVLSWSMIEAMSLGCALIASATPPVQEVVEQGENGILVDFFDRDGLAAAVADALDNPGAYEPMRQRARETAVERYDLRSKCLPEMLRYLSGEDDCGLYAVSG
>NC_010803.1|WP_012466781.1|2064179_2065823_-|glycosyltransferase-family-4-protein
MNSAILFEPDGYVLSGEKLMGRHAAGHAFLRAAVSGRDGLPLLAYTPHRGSFDVFTRLVHAFDPSAETRWISANRLDLLERSGTLYIPGPGLDTQAWLRLRRGITAYSVCGVTHTTASHGAMDSIAGLLEAPVMEWDALICTSEAVRESVRLVLDAGRDYLQWRFGSVRQLTIPKLPVIPLGVHCDDFRFDEAERKAAREALGISDSAVVALFAGRLSFHAKAHPFAMYAALQQVAERSGRELVLVQSGWFANDHIGNAFSSGSELFCPGVRVLCTDGRKPEERRRSWAAADLFISLSDNIQETFGLTPIEAMAAGLPSLVTDWDGYRDTVRDGIDGFRIATRMPEKGCGSFLAEAHESGSMGYDMYCGYACQLVSLDISALVLRLSELCGNPELRFSMGIAARKRAEEVFDWRVIFSRYKELWQELDAVRAAAVGRSGAVPACSPARMDPFTVFQHYSTFSVNRLSAVSLQPGSGMQHYRQRLAHPLFSYAAGLLPKPGEMERFFLFLMARGTCIIGDIAREIGLDESSIIRAVVMLEKMDIVTIS
>NC_010803.1|WP_012466780.1|2058202_2063770_-|DUF4347-domain-containing-protein
MSNSIYFFDSRVTDIETLIEALPSGSSYVILDSDKDGMRQIAAALAGKTGIDSIQLVSYGSSGTVMLGSTVLTASNLAKYRNELASIGSSLSADGDILLYGCNVGEGVAGKVFVDRLASYTGADVAASVNKTGKGGDWVLEVSSGSIEADSSVFAAAGYEYSLDITGTPGNDALTGTSSADTMYGLAGNDTLNGAGGNDSIDGGEGNDSLNGSTGDDTLIGGSGNDTLNGGSGNDSMVGGSGNDIYYVDSLGDGVLEGLDEGTDRVYSSLAAYTLSDNVENLNLQGAAFHGTGNDLDNSIVGNNSSNSLDGGEGNDSLSGSAGDDTLIGGPGLGNDTLNGGSGSDSMVGGSGNDTYYIDSGTDEIVESLDGGTDRVYSSLISYDMEANVENLILQDGDALFGYGNLLDNSITGNDSDNVLYGGDGNDSLNGGDGNDSLNGGNHNDSLNGGNGNDLLDGGEGNDTLIGGTGTGSGDDTLYGYAGNDSLTGYDGDDSLFGGEENDTLSGGNGNDMLDGGMGIDSMVGGAGNDTYYVDHANDRVNETLVVNGTADHVYSSLSAYTLGNNVENLTLIEGAGDINGTGNTLDNVITGNSGNNTLSGGAGNDTLNGGAGIDSMAGGTGNDTYYVNDPGDVVTETSGGGTADHVYASFSYTLTDNSYIENLTLQEGAGDIVGIGNASDNVLTGSNGNNTLDGALGNDTLDGGAGSDYLDGGAGDDWLSDEDAGGGSNTLDGGDGNDTVDAGYGTQSVTGGAGDDILSVYEATGVLDGGDGADVLDGEYGTYTMTGGSGNDDLYGYYFGGTMSGGADDDNMYVGYGSGTVTMTGDGGNDTLEGQNSTAVLSGDLGNDVVDARHGTYTLTGGEGDDEVSADDATGVLEGGSGNDVVDGEYGTYTMTGGTGNDEMYGYYFSGNMSGNEDDDLMYVGYGEGASVTMSGGSGNDTLIGDLGGTYQMAGDAGNDELYGYTGNDTLDGGAGSDSLDGGAGNDWLSDEDAGGGSNTLEGGDGNDTVDAGYGTQSVTGGAGDDILSVYEATGVLDGGDGADVLDGEYGTYTMTGGSGNDDLYGYYFGGTMSGGADDDNMYVGYGSGTVTMTGDGGNDTLEGQNSTAVLSGDAGDDLVDARHGTYTLTGGEGDDEVSADDATGVLEGGSGNDVVDGEYGTYTMTGGTGNDEMYGYYFSGNMSGNEDDDLMYLGYGEGTSVTMSGDSGNDTLIGDLAGTYQMAGDAGNDELYGDTGNDTLDGGAGSDYLDGGAGDDWLSDEDAEGGSNTLDGGDGNDTVDAGYGTQSVTGGAGDDILSVYEATGVLDGGDGADVLDGEYGTYTMTGGSGNDDLYGYYFGGTMSGGADDDNMYVGYGSGTVTMTGDGGNDTLEGQNSTAVLSGDLGNDVVDARHGTYTLTGGEGDDEVSADDATGVLEGGSGNDVVDGEYGTYTMTGGTGNDEMYGYYFSGSMSGNEDNDNMYVGFGEGASVTMSGGSGNDTMLGDLGGTYLMAGDEGNDELYGYTGNDTLDGGAGNDLVAGASGNDLLYGNEGDDSVYGGFGINTLYGGSGNDSVDGGEMQDFAFGEDGDDTIRGLYGNDVIDGGAGNDLLYGGDNYWQNSYDGNDTISGGAGNDTIDGEAGDDFLNGGSGDDNMFGGYGVIWGYNTIEFSGNDTMFGEDGNDILDGGLDNDSLDGGAGNDYLEGGAGDDFLRDLSGNNTLMGGAGNDYLDGGAENDYLDGGEGADTLLGWDGNDVLLFDENDAVIDGGNGIDTLILGTDASYSFSDIVSDVSVLHMEAIDLTANGNHTLSNVTAADVAAYANGIYILGDSGDTLTSTDTWSDTGDQIVNGITFDIYTSGSATVNIQRGITLA
>NC_010803.1|WP_190275071.1|2057906_2058092_-|hypothetical-protein
MKRMKPEEVEEILDFGLWIVDCGLWGGERLLRIALLEDGKRFWIGWRGVLALLCYQAVLLL
>NC_010803.1|WP_012466779.1|2056742_2057915_+|DNA-polymerase-III-subunit-delta'
MSWKTIIGQKQQIRVLQKALETGRLAHAYLFTGPEASGKESVAFELARTLNCRNKNRAPETGSCGTCPDCMQIDSFMHANIEYIFPVEAALLDSGESAKKENKKFSETKERYEALLEEKKLNPYLTPAMERSMGILSEQIVTLQQKALYRPSEGQRKIFIISQADRMNPAAANKILKLLEEPPAHILFILISSRPEAVLPTIRSRCQIVRFQRPGPMELRKWIQENRPDIHEPELGFIVSFSRGNLALAWDLINQGGVTGNIPVIQLRNQALDYLRLVLTPSRLHEALSACESHAKNLSKTELPLFLGALLLFLQDVNHRLIDPEFQTLNNPDIAASIDRFAKNFPTPDFLAISTITEEAIRAIDRNANPLLVLAAWTSEIKNLILAKSQ
>NC_010803.1|WP_012466778.1|2055813_2056725_+|branched-chain-amino-acid-transaminase
MNKSEKIWMNGELINWSDAKIHILSHAIHYGSSIFEGIRCYETAKGSAVLFLDEHIKRLRDSSKIYRIEIPYSEQELREAIIATIKVNAHKSCYVRPIVYRGQGALGVNPARASIEVAIATWEWGTYLGEDVLENGVDVRVSSWNRLSPNTLPSWAKAGGNYLNSQLIKMEALMDDYAEGLALDHNGYVSEGSGENIFVIRNGVIYTPMTAQSILPGFTRYAVIHIARELGYEVHETLIPREALYVADEVFLTGTAAEITPVRSIDKYPVGNEKRGPITEVLQHHYLKIVQTGEDPYNWLTFI
>NC_010803.1|WP_012466777.1|2053635_2054931_-|hypothetical-protein
MIFSHGNPYRGEHGLPDILYLSPDDFTVTISRMNLNAVDHVAKWTILIYMAADCDLAAFMFDDLMEMKVVGSNEDVNICVFFDGPLLTDTFFARLCHGTSLEEDIIQRFTDVPSSNVGILKEIILNTAVLFPAERRVLVLAGHGLGWRGALRDDSTWKRFKERRAIVMPSGDSSVFFRQLDEQRQRALEELKARLNPRDEHHGSAFDIIAMDACNMGNLEALSFYSDHARILVASENQVPASGYPYDRILEELKRNPEQECDAFARYLVNEVKRYYVDSILLCSESDITQVAFDSTGFPALIAHAGELARVLSEYVSTEGIATVKACSGASLLPEEDTDYIDLRLFAKELVQAGVSDAVKQKAMELVAFFDGSGFVVGSATPGGDALPKGLSIYFPPPERFDKGYLDILSHVPEGIRLWAGFIGAYYGKRF
>NC_010803.1|WP_041465748.1|2051887_2052982_-|DUF4407-domain-containing-protein
MGFSQMQRFFWVCSGTPVDMIEKYSTEHSKYLGIGATIVFTALFAGLSGGYALYFVFAGNVFAPLWSVAFGLLWGLAIFNLDRYIVSSINKTSKGMKQFYQASPRFIFAVLIAIVIARPLELKIFDKEIHERLKERYLMDQKAQIGRVQLSFNEKYAQELSQIRKYQAEYDLLSGDVNRLREELKEEVFGSKTNTTSGVPGYGAYAKNKEAVVGAKQLRLEFLASQLADLQAYMNRQKADEGINKQMMLTEDLLDRKAAHAGFADRNWALGELTRSGDNVSRSSAAAVQFITLLFIAFECAPLIVKLLSDAGPSDVEGNETERRIIAQLTNTAFLNRNRIVRQYRFLGAKSGRRYARRYVGQKR
>NC_010803.1|WP_012466775.1|2048140_2048512_-|four-helix-bundle-protein
MRCETLDVWKISARLSADVYKTISPGKDFGFRDQICRSGLSIPSNIAEGMEKESIRERIKFLDIAKGSAAEFITQVYIGNDIDYITSETSQNWIQTAEHVLSMLNKLQQTLKSQLPAKTHHSH
>NC_010803.1|WP_012466785.1|2081918_2082944_-|metallophosphoesterase
MYTHTALFKKYSGVFLVKKKTILNAYLFAVIILFFPFSGKASVHFLATADPQYDNGNSAVNQQANKTLLTMLASIKCNNDIKGIIVAGDLTQNSRIYDEFSWYNNALSIQNKVTGDVVDMSAYVYDGIGNHDKAEPTFMQKTACFFKTAECVNPEVIQNTLSSRVRLTPVLYREGIHYAWKWDDVVFVQLNLFPGDSNDNYGLSPQNSLTYLRNLLNNRVDKNKDRIVLIHHYGFDPFSQTYWSDSQRKEYWNLIADYNVMGILTGHSHNNTGYTFYNAFTRPSGYTKGPASIASFVCGGACLGYYLDITIDGNTMHVRQRDNNGTQKKAVLVDNGVIYYR
>NC_010803.1|WP_012466786.1|2083432_2083780_+|hypothetical-protein
MQNKTITRILALSIITATFPSYNVSAVPPTASDHSATAASGSIGATVGLAISIGLPKENKNSPGNPGGPGGNPGNQGGPGGNPGNPSGGAGNPGGPGGNPGNPGRGNSGGGNPGR
>NC_010803.1|WP_012466787.1|2084610_2085603_-|NAD-dependent-epimerase/dehydratase-family-protein
MLKRVLLIGASGFVGTRLIETIGEKRCINIDKQNSSRYNNITLIHDIRNDGIDVAISHQPSSIVLLAAEHRDDVSPISLYYDVNVQGTKNVLDAMDHKGIKSIIFTSSVAVYGLNKKISDETHQADPFNHYGKSKWEAEEVLREWYQKDPENRSLSIIRPTVIFGEANRGNVYNLLKQIALGKFLMIGKGENKKSMAYVGNVVVFIKYLIENDKPGYRVYNYVDKPDFNMNELVHQVRHDLGQDGKMIRIPEWLGMLGGYGFDIAAKLSGKKLPISSVRVKKFCATTQFSADKLDKSGFIRPYTIEEGLERTLRYEFLEKNDDKHVFYTE
>NC_010803.1|WP_012466788.1|2085858_2087013_-|hypothetical-protein
MKKYIYFYDLNEKLLARYPAKISQEILSTHQDAEFVYLYSERYEKKGNPDKLPEGSKVVYLPTLSMTKIQKLFKTHPPALFITIGMRLPDILMLSFFNRHQVPTCMVQHGLFIKHLERIPLHLVIGQKLIKFTQYLIYSYKISRVLKKSFLKTLYELYLYFIKGSHKIPQLKHINSSLILAKTAFIFDDNWKKYYFITYGYTEEQFYKIGNPDFLILKQLKSAVQENAVCYICQSLVEDGRYLRSDFMCYIKEIEENLADDIKVYFKMHPRSRMELYEELNTDKINFTQEFPNCKFYLGHYSSLLAVAHDISQVIIWNLKGHQTPAEYVKYADMISNDWEEVRSFIRIKQQDNTTKDFDASYMEDSFNPYYHIAQFINQKATDF
>NC_010803.1|WP_012466789.1|2087014_2087779_-|2,4-dihydroxyhept-2-ene-1,7-dioic-acid-aldolase
MKNTRLKGQLKNNEQTLGSWVTIGHPAVVEVLSNANFDWLTIDIEHNNIDPAMLTTLIATIQSKNIAALVRVSKNEEVPIKHAMDAGADGVIVPMVNSREDAEKAVEYVKYPPRGKRGVGLSRAQNYGIGFESYKQWLQAYSVIIAQIEHIDGVRNIEQIIEVPDIDAIIIGPYDLSGSLGYPGNYSREDVREALIRVEQVCRERNFPMGFHVVPPDVEEVAIRRAAGYSFIAFSTDFLLMGDTATKLVNHLRK
>NC_010803.1|WP_012466790.1|2087775_2088447_-|cyclase-family-protein
MIFLSHHYASDTPTYGDRDKFKVAANSTIAGGGTANSSSWVFTNNHIGTHIDTPYHFNRNGMQTLDYPADFWYFNRVEIIDIPCNAARIIGPEAVAGCIIDPGTEMLLIRTGYELVRQEDKYWNDNPGLAPELADYLRSNFSKMRVIGFDFISITSWKHRQLGRESHKAFLVPGPGRIPILAIEDMALQAVHESIEWALVSPLRTEEGNGCPVTVFAKLTSDS
>NC_010803.1|WP_049754361.1|2088451_2089096_-|acylneuraminate-cytidylyltransferase-family-protein
MKGHSERVPNKNLRPVAGKPCFHWIIESLERSPYIGEIVINTDSDEIAESAKKNFQVTILERPDYLLGDMVSIQPLIEYDLSMTEGDYYLQTHSTNPLVTTETINNSIKTFFNQKEHDALFTVTPIKTRFYRADGSGVNHDPRHLIRTQDLDPIFEENSCLYIFSKKTNEQIRNRLGANPMMYPMDHLEAVDIDDMHDLLWAEFLLNQRLTRKL
>NC_010803.1|WP_012466792.1|2089141_2090425_-|right-handed-parallel-beta-helix-repeat-containing-protein
MKSGLRSIFLILWCGLLPAKNGSAYAAFNTFSRVSDLNSLRQLSEQMVFVLGYSEPGDGGGGWFRWEPNIMEEPDGSMRIRPHSFKQGCFARVTDGAGLNVKWFGAKGDGKHNDTEAIQSAIEWASARQSFFQQSIAVRDLVLIPSGQFLVDSLELKSGVILQGAGQFSSVILHTGNSSRCIYNEKGHHNRWVGIRELTVIGSDNKGTYTEGIHLFEANYSSYINRITIRGFTQNIVLEDCWTFQLTRSHLFKAHRNNLTILNGTAMEISGNRIDGAGKSNIQISRSKRYRNTGILIRNNAIQQAQEYGLYCRDTNSLLLEGNFFEANNRNGGFAFVYIEGPQTSKHCLIHSTSNYFSGANKSAPNSVGIFLKGNVKSFSSNQDYFSGSMGYGIYSVDLQSKEFVISGTTFHSKSDLKLPSDIKIIN
>NC_010803.1|WP_012466793.1|2090428_2090881_-|YhcH/YjgK/YiaL-family-protein
MIVDTLQNIETYKNLSEDIYAGLKFLSELKPDIELGEYHINERVKAIVSEYETIEEFTRGYEAHKHVVDIQYPIKGLERVKWSNIVGMDVNISYDEKKDRTFFKNPFPQMTHVDIGNGVFAIMFPQDGHGPQHYVSQPEMIKKVTVKVSI
>NC_010803.1|WP_150081661.1|2090887_2091967_-|3-dehydroquinate-synthase
MGDIQMYNFKVTSIIHDYEVHFIDSLKQSIDSVLMEGDYIIIDNIVKDLYDEYLQDALDTHKFIGIDANEKTKSYQGVESVIEELIQNGFRKNHRLVAIGGGITQDVTAFISSIMYRGVNWIFYPTTMLAQGDSCIGSKTSINFGRFKNQVGGFYPPSYIYIFPPFKDTLKEKEIRSGMGEMLHYFIVSGKEDFDFYRDTFKAAFTEKDALSGIINKSLEIKKRYIEIDEFDKKERQVFNYGHTFGHAIESLTQYRIPHGIAVSYGMDMSNFVSVKMGLIPSEVRDEIREVTSYIWEGYPIDDIDIDTYINALSKDKKNVGMQLGLILNKGYGNIFKNLTDSDKTFREWIEEYFLNELK

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Crispr_ID: NC_010803_12

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_010803_12

2075726-2075830

Orphan

Consensus_repeat	Method
GCCTGCACCGCCGTCAAGCAGATC	CRISPRCasFinder

1 spacers

The CRISPR arrays of NC_010803_12

>merge|NC_010803|12|2075726-2075830|CRISPRCasFinder
GCCTGCACCGCCGTCAAGCAGATCATCGCCTTCACCGCCATAGAGCGTATCGCTGTCGCCTTCACCGTAAAGTTCGTCGTTGCCTGCACCGCCGTCAAGCAGATC

>NC_010803|12|11|2075726-2075830|CRISPRCasFinder
GCCTGCACCGCCGTCAAGCAGATC	ATCGCCTTCACCGCCATAGAGCGTATCGCTGTCGCCTTCACCGTAAAGTTCGTCGTT
GCCTGCACCGCCGTCAAGCAGATC

Protein	Signature genes	Signature genes Name	Protein_function
NC_010803.1\|WP_041465748.1\|2051887_2052982_-\|DUF4407-domain-containing-protein	unknown	unknown	gnl\|CDD\|379583
NC_010803.1\|WP_012466780.1\|2058202_2063770_-\|DUF4347-domain-containing-protein	unknown	unknown	gnl\|CDD\|372982
NC_010803.1\|WP_012466781.1\|2064179_2065823_-\|glycosyltransferase-family-4-protein	unknown	unknown	gnl\|CDD\|340831
NC_010803.1\|WP_012466790.1\|2087775_2088447_-\|cyclase-family-protein	unknown	unknown	gnl\|CDD\|224790
NC_010803.1\|WP_012466785.1\|2081918_2082944_-\|metallophosphoesterase	unknown	unknown	unknown
NC_010803.1\|WP_190275071.1\|2057906_2058092_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|369956
NC_010803.1\|WP_012466777.1\|2053635_2054931_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|281416
NC_010803.1\|WP_150081661.1\|2090887_2091967_-\|3-dehydroquinate-synthase	unknown	unknown	gnl\|CDD\|275218
NC_010803.1\|WP_012466792.1\|2089141_2090425_-\|right-handed-parallel-beta-helix-repeat-containing-protein	unknown	unknown	gnl\|CDD\|378931
NC_010803.1\|WP_012466775.1\|2048140_2048512_-\|four-helix-bundle-protein	unknown	unknown	gnl\|CDD\|183395
NC_010803.1\|WP_190275115.1\|2067538_2068096_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|380205
NC_010803.1\|WP_012466778.1\|2055813_2056725_+\|branched-chain-amino-acid-transaminase	unknown	unknown	gnl\|CDD\|235841
NC_010803.1\|WP_049754361.1\|2088451_2089096_-\|acylneuraminate-cytidylyltransferase-family-protein	unknown	unknown	gnl\|CDD\|133006
NC_010803.1\|WP_012466789.1\|2087014_2087779_-\|2,4-dihydroxyhept-2-ene-1,7-dioic-acid-aldolase	unknown	unknown	gnl\|CDD\|226356
NC_010803.1\|WP_012466788.1\|2085858_2087013_-\|hypothetical-protein	unknown	unknown	unknown
NC_010803.1\|WP_041466011.1\|2066203_2067457_-\|glycosyltransferase-family-4-protein	unknown	unknown	gnl\|CDD\|340845
NC_010803.1\|WP_012466793.1\|2090428_2090881_-\|YhcH/YjgK/YiaL-family-protein	unknown	unknown	gnl\|CDD\|225345
NC_010803.1\|WP_012466779.1\|2056742_2057915_+\|DNA-polymerase-III-subunit-delta'	unknown	unknown	gnl\|CDD\|379051
NC_010803.1\|WP_012466787.1\|2084610_2085603_-\|NAD-dependent-epimerase/dehydratase-family-protein	unknown	unknown	gnl\|CDD\|187549
NC_010803.1\|WP_012466786.1\|2083432_2083780_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|240291

Protein	Function_ID	Function_description	E-value
NC_010803.1\|WP_041465748.1\|2051887_2052982_-\|DUF4407-domain-containing-protein	gnl\|CDD\|379583	pfam14362, DUF4407, Domain of unknown function (DUF4407). This family of proteins is found in bacteria. Proteins in this family are typically between 366 and 597 amino acids in length. There is a single completely conserved residue R that may be functionally important.	1.53621e-98
NC_010803.1\|WP_012466780.1\|2058202_2063770_-\|DUF4347-domain-containing-protein	gnl\|CDD\|372982	pfam14252, DUF4347, Domain of unknown function (DUF4347). This domain family is found in bacteria and eukaryotes, and is approximately 160 amino acids in length. There are two completely conserved residues (C and G) that may be functionally important.	3.76026e-53
NC_010803.1\|WP_012466781.1\|2064179_2065823_-\|glycosyltransferase-family-4-protein	gnl\|CDD\|340831	cd03801, GT4_PimA-like, phosphatidyl-myo-inositol mannosyltransferase. This family is most closely related to the GT4 family of glycosyltransferases and named after PimA in Propionibacterium freudenreichii, which is involved in the biosynthesis of phosphatidyl-myo-inositol mannosides (PIM) which are early precursors in the biosynthesis of lipomannans (LM) and lipoarabinomannans (LAM), and catalyzes the addition of a mannosyl residue from GDP-D-mannose (GDP-Man) to the position 2 of the carrier lipid phosphatidyl-myo-inositol (PI) to generate a phosphatidyl-myo-inositol bearing an alpha-1,2-linked mannose residue (PIM1). Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate residue. This group of glycosyltransferases is most closely related to the previously defined glycosyltransferase family 1 (GT1). The members of this family may transfer UDP, ADP, GDP, or CMP linked sugars. The diverse enzymatic activities among members of this family reflect a wide range of biological functions. The protein structure available for this family has the GTB topology, one of the two protein topologies observed for nucleotide-sugar-dependent glycosyltransferases. GTB proteins have distinct N- and C- terminal domains each containing a typical Rossmann fold. The two domains have high structural homology despite minimal sequence homology. The large cleft that separates the two domains includes the catalytic center and permits a high degree of flexibility. The members of this family are found mainly in certain bacteria and archaea.	1.36018e-25
NC_010803.1\|WP_150081661.1\|2090887_2091967_-\|3-dehydroquinate-synthase	gnl\|CDD\|275218	TIGR04425, 3-dehydroquinate_synthase, putative sugar phosphate phospholyase (cyclizing). Members of this family tend to be found in O-antigen biosynthesis regions. Members frequently are misidentified as the closely related 3-dehydroquinate synthase, AroB (see family TIGR01357), the phospholyase that converts 3-deoxy-D-arabino-hept-2-ulosonate 7-phosphate to 3-dehydroquinate during chorismate biosynthesis. Most bacteria with this enzyme have a true AroB in a chorismate biosynthesis gene cluster. [Biosynthesis of cofactors, prosthetic groups, and carriers, Lipoate].	0
NC_010803.1\|WP_190275071.1\|2057906_2058092_-\|hypothetical-protein	gnl\|CDD\|369956	pfam08564, CDC37_C, Cdc37 C terminal domain. Cdc37 is a protein required for the activity of numerous eukaryotic protein kinases. This domains corresponds to the C terminal domain whose function is unclear. It is found C terminal to the Hsp90 chaperone (Heat shocked protein 90) binding domain pfam08565 and the N terminal kinase binding domain of Cdc37 pfam03234.	0.00421149
NC_010803.1\|WP_012466777.1\|2053635_2054931_-\|hypothetical-protein	gnl\|CDD\|281416	pfam03415, Peptidase_C11, Clostripain family.	1.01605e-18
NC_010803.1\|WP_012466792.1\|2089141_2090425_-\|right-handed-parallel-beta-helix-repeat-containing-protein	gnl\|CDD\|378931	pfam12708, Pectate_lyase_3, Pectate lyase superfamily protein. This family of proteins possesses a beta helical structure like Pectate lyase. This family is most closely related to glycosyl hydrolase family 28.	5.21861e-10
NC_010803.1\|WP_012466775.1\|2048140_2048512_-\|four-helix-bundle-protein	gnl\|CDD\|183395	PRK12275, PRK12275, hypothetical protein; Reviewed.	1.66951e-39
NC_010803.1\|WP_190275115.1\|2067538_2068096_-\|hypothetical-protein	gnl\|CDD\|380205	NF033203, entero_EhxA, enterohemolysin EhxA. Members of this family are the RTX toxin called enterohemolysin or EhxA, because it is found in enterohemorrhagic Escherichia coli (EHEC) strains such as O157:H7.	2.67448e-10
NC_010803.1\|WP_012466778.1\|2055813_2056725_+\|branched-chain-amino-acid-transaminase	gnl\|CDD\|235841	PRK06606, PRK06606, branched-chain amino acid transaminase.	0
NC_010803.1\|WP_049754361.1\|2088451_2089096_-\|acylneuraminate-cytidylyltransferase-family-protein	gnl\|CDD\|133006	cd02513, CMP-NeuAc_Synthase, CMP-NeuAc_Synthase activates N-acetylneuraminic acid by adding CMP moiety. CMP-N-acetylneuraminic acid synthetase (CMP-NeuAc synthetase) or acylneuraminate cytidylyltransferase catalyzes the transfer the CMP moiety of CTP to the anomeric hydroxyl group of NeuAc in the presence of Mg++. It is the second to last step in the sialylation of the oligosaccharide component of glycoconjugates by providing the activated sugar-nucleotide cytidine 5'-monophosphate N-acetylneuraminic acid (CMP-Neu5Ac), the substrate for sialyltransferases. Eukaryotic CMP-NeuAc synthetases are predominantly located in the nucleus. The activated CMP-Neu5Ac diffuses from the nucleus into the cytoplasm.	2.01937e-63
NC_010803.1\|WP_012466789.1\|2087014_2087779_-\|2,4-dihydroxyhept-2-ene-1,7-dioic-acid-aldolase	gnl\|CDD\|226356	COG3836, HpcH, 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase [Carbohydrate transport and metabolism].	1.57493e-56
NC_010803.1\|WP_012466790.1\|2087775_2088447_-\|cyclase-family-protein	gnl\|CDD\|224790	COG1878, COG1878, Kynurenine formamidase [Amino acid transport and metabolism].	2.86041e-26
NC_010803.1\|WP_041466011.1\|2066203_2067457_-\|glycosyltransferase-family-4-protein	gnl\|CDD\|340845	cd03818, GT4_ExpC-like, Rhizobium meliloti ExpC and similar proteins. This family is most closely related to the GT4 family of glycosyltransferases. ExpC in Rhizobium meliloti has been shown to be involved in the biosynthesis of galactoglucan (exopolysaccharide II).	6.0575e-173
NC_010803.1\|WP_012466793.1\|2090428_2090881_-\|YhcH/YjgK/YiaL-family-protein	gnl\|CDD\|225345	COG2731, EbgC, Beta-galactosidase, beta subunit [Carbohydrate transport and metabolism].	2.59014e-26
NC_010803.1\|WP_012466779.1\|2056742_2057915_+\|DNA-polymerase-III-subunit-delta'	gnl\|CDD\|379051	pfam13177, DNA_pol3_delta2, DNA polymerase III, delta subunit. DNA polymerase III, delta subunit (EC 2.7.7.7) is required for, along with delta' subunit, the assembly of the processivity factor beta(2) onto primed DNA in the DNA polymerase III holoenzyme-catalyzed reaction. The delta subunit is also known as HolA.	1.0563e-58
NC_010803.1\|WP_012466787.1\|2084610_2085603_-\|NAD-dependent-epimerase/dehydratase-family-protein	gnl\|CDD\|187549	cd05238, Gne_like_SDR_e, Escherichia coli Gne (a nucleoside-diphosphate-sugar 4-epimerase)-like, extended (e) SDRs. Nucleoside-diphosphate-sugar 4-epimerase has the characteristic active site tetrad and NAD-binding motif of the extended SDR, and is related to more specifically defined epimerases such as UDP-glucose 4 epimerase (aka UDP-galactose-4-epimerase), which catalyzes the NAD-dependent conversion of UDP-galactose to UDP-glucose, the final step in Leloir galactose synthesis. This subgroup includes Escherichia coli 055:H7 Gne, a UDP-GlcNAc 4-epimerase, essential for O55 antigen synthesis. Extended SDRs are distinct from classical SDRs. In addition to the Rossmann fold (alpha/beta folding pattern with a central beta-sheet) core region typical of all SDRs, extended SDRs have a less conserved C-terminal extension of approximately 100 amino acids. Extended SDRs are a diverse collection of proteins, and include isomerases, epimerases, oxidoreductases, and lyases; they typically have a TGXXGXXG cofactor binding motif. SDRs are a functionally diverse family of oxidoreductases that have a single domain with a structurally conserved Rossmann fold, an NAD(P)(H)-binding region, and a structurally diverse C-terminal region. Sequence identity between different SDR enzymes is typically in the 15-30% range; they catalyze a wide range of activities including the metabolism of steroids, cofactors, carbohydrates, lipids, aromatic compounds, and amino acids, and act in redox sensing. Classical SDRs have an TGXXX[AG]XG cofactor binding motif and a YXXXK active site motif, with the Tyr residue of the active site motif serving as a critical catalytic residue (Tyr-151, human 15-hydroxyprostaglandin dehydrogenase numbering). In addition to the Tyr and Lys, there is often an upstream Ser and/or an Asn, contributing to the active site; while substrate binding is in the C-terminal region, which determines specificity. The standard reaction mechanism is a 4-pro-S hydride transfer and proton relay involving the conserved Tyr and Lys, a water molecule stabilized by Asn, and nicotinamide. Atypical SDRs generally lack the catalytic residues characteristic of the SDRs, and their glycine-rich NAD(P)-binding motif is often different from the forms normally seen in classical or extended SDRs. Complex (multidomain) SDRs such as ketoreductase domains of fatty acid synthase have a GGXGXXG NAD(P)-binding motif and an altered active site motif (YXXXN). Fungal type ketoacyl reductases have a TGXXXGX(1-2)G NAD(P)-binding motif.	3.46239e-69
NC_010803.1\|WP_012466786.1\|2083432_2083780_+\|hypothetical-protein	gnl\|CDD\|240291	PTZ00146, PTZ00146, fibrillarin; Provisional.	0.000227851

>NC_010803.1|WP_190275115.1|2067538_2068096_-|hypothetical-protein
MLDGDSGNDTLYGGEGTDSMKGRAGNDSLDGGFGDDMLDGGAGSDYLDGSYGTDMLYGGDGDDTLVFDRYDAMIDGEDGFDTLVFAGDDNFGFGELLTSGVVGIELIDLTSGSHALTDITSDDVASVLGGGTELFINGDTYDTVGLGSGWTNTGSSEIGGVSYNGYNSDGMNVYVQSGIAVQQES
>NC_010803.1|WP_041466011.1|2066203_2067457_-|glycosyltransferase-family-4-protein
MNFLFVHQNFPGQFPHVARALAGMPGNRVVAIAEEKNVVQRLPVHPNVVVKTYRQEKGSGRETHHYIRDFESAVRRGQTVARLAIEIRKSGFHPHVVVGHPAWGETLFLKDVFPNARHISYFEFFYRADGGDVGFDPEFPSVFDDRLRIRVKNTTQLLSLEAADAGISPTLWQQSRFPEEFHSKIRVIHEGVDTAFVRPDPDAAVELDGMTLKRCDKVVTFLSRNLEPYRGFHVFMRTLPLIQKACPEARIVIIGGDGVSYGRRLPEGQTYRAMYAAEAGDKVDWSKVHFTGRVPYNRYLSLLQVSSAHIYLTYPFVLSWSMIEAMSLGCALIASATPPVQEVVEQGENGILVDFFDRDGLAAAVADALDNPGAYEPMRQRARETAVERYDLRSKCLPEMLRYLSGEDDCGLYAVSG
>NC_010803.1|WP_012466781.1|2064179_2065823_-|glycosyltransferase-family-4-protein
MNSAILFEPDGYVLSGEKLMGRHAAGHAFLRAAVSGRDGLPLLAYTPHRGSFDVFTRLVHAFDPSAETRWISANRLDLLERSGTLYIPGPGLDTQAWLRLRRGITAYSVCGVTHTTASHGAMDSIAGLLEAPVMEWDALICTSEAVRESVRLVLDAGRDYLQWRFGSVRQLTIPKLPVIPLGVHCDDFRFDEAERKAAREALGISDSAVVALFAGRLSFHAKAHPFAMYAALQQVAERSGRELVLVQSGWFANDHIGNAFSSGSELFCPGVRVLCTDGRKPEERRRSWAAADLFISLSDNIQETFGLTPIEAMAAGLPSLVTDWDGYRDTVRDGIDGFRIATRMPEKGCGSFLAEAHESGSMGYDMYCGYACQLVSLDISALVLRLSELCGNPELRFSMGIAARKRAEEVFDWRVIFSRYKELWQELDAVRAAAVGRSGAVPACSPARMDPFTVFQHYSTFSVNRLSAVSLQPGSGMQHYRQRLAHPLFSYAAGLLPKPGEMERFFLFLMARGTCIIGDIAREIGLDESSIIRAVVMLEKMDIVTIS
>NC_010803.1|WP_012466780.1|2058202_2063770_-|DUF4347-domain-containing-protein
MSNSIYFFDSRVTDIETLIEALPSGSSYVILDSDKDGMRQIAAALAGKTGIDSIQLVSYGSSGTVMLGSTVLTASNLAKYRNELASIGSSLSADGDILLYGCNVGEGVAGKVFVDRLASYTGADVAASVNKTGKGGDWVLEVSSGSIEADSSVFAAAGYEYSLDITGTPGNDALTGTSSADTMYGLAGNDTLNGAGGNDSIDGGEGNDSLNGSTGDDTLIGGSGNDTLNGGSGNDSMVGGSGNDIYYVDSLGDGVLEGLDEGTDRVYSSLAAYTLSDNVENLNLQGAAFHGTGNDLDNSIVGNNSSNSLDGGEGNDSLSGSAGDDTLIGGPGLGNDTLNGGSGSDSMVGGSGNDTYYIDSGTDEIVESLDGGTDRVYSSLISYDMEANVENLILQDGDALFGYGNLLDNSITGNDSDNVLYGGDGNDSLNGGDGNDSLNGGNHNDSLNGGNGNDLLDGGEGNDTLIGGTGTGSGDDTLYGYAGNDSLTGYDGDDSLFGGEENDTLSGGNGNDMLDGGMGIDSMVGGAGNDTYYVDHANDRVNETLVVNGTADHVYSSLSAYTLGNNVENLTLIEGAGDINGTGNTLDNVITGNSGNNTLSGGAGNDTLNGGAGIDSMAGGTGNDTYYVNDPGDVVTETSGGGTADHVYASFSYTLTDNSYIENLTLQEGAGDIVGIGNASDNVLTGSNGNNTLDGALGNDTLDGGAGSDYLDGGAGDDWLSDEDAGGGSNTLDGGDGNDTVDAGYGTQSVTGGAGDDILSVYEATGVLDGGDGADVLDGEYGTYTMTGGSGNDDLYGYYFGGTMSGGADDDNMYVGYGSGTVTMTGDGGNDTLEGQNSTAVLSGDLGNDVVDARHGTYTLTGGEGDDEVSADDATGVLEGGSGNDVVDGEYGTYTMTGGTGNDEMYGYYFSGNMSGNEDDDLMYVGYGEGASVTMSGGSGNDTLIGDLGGTYQMAGDAGNDELYGYTGNDTLDGGAGSDSLDGGAGNDWLSDEDAGGGSNTLEGGDGNDTVDAGYGTQSVTGGAGDDILSVYEATGVLDGGDGADVLDGEYGTYTMTGGSGNDDLYGYYFGGTMSGGADDDNMYVGYGSGTVTMTGDGGNDTLEGQNSTAVLSGDAGDDLVDARHGTYTLTGGEGDDEVSADDATGVLEGGSGNDVVDGEYGTYTMTGGTGNDEMYGYYFSGNMSGNEDDDLMYLGYGEGTSVTMSGDSGNDTLIGDLAGTYQMAGDAGNDELYGDTGNDTLDGGAGSDYLDGGAGDDWLSDEDAEGGSNTLDGGDGNDTVDAGYGTQSVTGGAGDDILSVYEATGVLDGGDGADVLDGEYGTYTMTGGSGNDDLYGYYFGGTMSGGADDDNMYVGYGSGTVTMTGDGGNDTLEGQNSTAVLSGDLGNDVVDARHGTYTLTGGEGDDEVSADDATGVLEGGSGNDVVDGEYGTYTMTGGTGNDEMYGYYFSGSMSGNEDNDNMYVGFGEGASVTMSGGSGNDTMLGDLGGTYLMAGDEGNDELYGYTGNDTLDGGAGNDLVAGASGNDLLYGNEGDDSVYGGFGINTLYGGSGNDSVDGGEMQDFAFGEDGDDTIRGLYGNDVIDGGAGNDLLYGGDNYWQNSYDGNDTISGGAGNDTIDGEAGDDFLNGGSGDDNMFGGYGVIWGYNTIEFSGNDTMFGEDGNDILDGGLDNDSLDGGAGNDYLEGGAGDDFLRDLSGNNTLMGGAGNDYLDGGAENDYLDGGEGADTLLGWDGNDVLLFDENDAVIDGGNGIDTLILGTDASYSFSDIVSDVSVLHMEAIDLTANGNHTLSNVTAADVAAYANGIYILGDSGDTLTSTDTWSDTGDQIVNGITFDIYTSGSATVNIQRGITLA
>NC_010803.1|WP_190275071.1|2057906_2058092_-|hypothetical-protein
MKRMKPEEVEEILDFGLWIVDCGLWGGERLLRIALLEDGKRFWIGWRGVLALLCYQAVLLL
>NC_010803.1|WP_012466779.1|2056742_2057915_+|DNA-polymerase-III-subunit-delta'
MSWKTIIGQKQQIRVLQKALETGRLAHAYLFTGPEASGKESVAFELARTLNCRNKNRAPETGSCGTCPDCMQIDSFMHANIEYIFPVEAALLDSGESAKKENKKFSETKERYEALLEEKKLNPYLTPAMERSMGILSEQIVTLQQKALYRPSEGQRKIFIISQADRMNPAAANKILKLLEEPPAHILFILISSRPEAVLPTIRSRCQIVRFQRPGPMELRKWIQENRPDIHEPELGFIVSFSRGNLALAWDLINQGGVTGNIPVIQLRNQALDYLRLVLTPSRLHEALSACESHAKNLSKTELPLFLGALLLFLQDVNHRLIDPEFQTLNNPDIAASIDRFAKNFPTPDFLAISTITEEAIRAIDRNANPLLVLAAWTSEIKNLILAKSQ
>NC_010803.1|WP_012466778.1|2055813_2056725_+|branched-chain-amino-acid-transaminase
MNKSEKIWMNGELINWSDAKIHILSHAIHYGSSIFEGIRCYETAKGSAVLFLDEHIKRLRDSSKIYRIEIPYSEQELREAIIATIKVNAHKSCYVRPIVYRGQGALGVNPARASIEVAIATWEWGTYLGEDVLENGVDVRVSSWNRLSPNTLPSWAKAGGNYLNSQLIKMEALMDDYAEGLALDHNGYVSEGSGENIFVIRNGVIYTPMTAQSILPGFTRYAVIHIARELGYEVHETLIPREALYVADEVFLTGTAAEITPVRSIDKYPVGNEKRGPITEVLQHHYLKIVQTGEDPYNWLTFI
>NC_010803.1|WP_012466777.1|2053635_2054931_-|hypothetical-protein
MIFSHGNPYRGEHGLPDILYLSPDDFTVTISRMNLNAVDHVAKWTILIYMAADCDLAAFMFDDLMEMKVVGSNEDVNICVFFDGPLLTDTFFARLCHGTSLEEDIIQRFTDVPSSNVGILKEIILNTAVLFPAERRVLVLAGHGLGWRGALRDDSTWKRFKERRAIVMPSGDSSVFFRQLDEQRQRALEELKARLNPRDEHHGSAFDIIAMDACNMGNLEALSFYSDHARILVASENQVPASGYPYDRILEELKRNPEQECDAFARYLVNEVKRYYVDSILLCSESDITQVAFDSTGFPALIAHAGELARVLSEYVSTEGIATVKACSGASLLPEEDTDYIDLRLFAKELVQAGVSDAVKQKAMELVAFFDGSGFVVGSATPGGDALPKGLSIYFPPPERFDKGYLDILSHVPEGIRLWAGFIGAYYGKRF
>NC_010803.1|WP_041465748.1|2051887_2052982_-|DUF4407-domain-containing-protein
MGFSQMQRFFWVCSGTPVDMIEKYSTEHSKYLGIGATIVFTALFAGLSGGYALYFVFAGNVFAPLWSVAFGLLWGLAIFNLDRYIVSSINKTSKGMKQFYQASPRFIFAVLIAIVIARPLELKIFDKEIHERLKERYLMDQKAQIGRVQLSFNEKYAQELSQIRKYQAEYDLLSGDVNRLREELKEEVFGSKTNTTSGVPGYGAYAKNKEAVVGAKQLRLEFLASQLADLQAYMNRQKADEGINKQMMLTEDLLDRKAAHAGFADRNWALGELTRSGDNVSRSSAAAVQFITLLFIAFECAPLIVKLLSDAGPSDVEGNETERRIIAQLTNTAFLNRNRIVRQYRFLGAKSGRRYARRYVGQKR
>NC_010803.1|WP_012466775.1|2048140_2048512_-|four-helix-bundle-protein
MRCETLDVWKISARLSADVYKTISPGKDFGFRDQICRSGLSIPSNIAEGMEKESIRERIKFLDIAKGSAAEFITQVYIGNDIDYITSETSQNWIQTAEHVLSMLNKLQQTLKSQLPAKTHHSH
>NC_010803.1|WP_012466785.1|2081918_2082944_-|metallophosphoesterase
MYTHTALFKKYSGVFLVKKKTILNAYLFAVIILFFPFSGKASVHFLATADPQYDNGNSAVNQQANKTLLTMLASIKCNNDIKGIIVAGDLTQNSRIYDEFSWYNNALSIQNKVTGDVVDMSAYVYDGIGNHDKAEPTFMQKTACFFKTAECVNPEVIQNTLSSRVRLTPVLYREGIHYAWKWDDVVFVQLNLFPGDSNDNYGLSPQNSLTYLRNLLNNRVDKNKDRIVLIHHYGFDPFSQTYWSDSQRKEYWNLIADYNVMGILTGHSHNNTGYTFYNAFTRPSGYTKGPASIASFVCGGACLGYYLDITIDGNTMHVRQRDNNGTQKKAVLVDNGVIYYR
>NC_010803.1|WP_012466786.1|2083432_2083780_+|hypothetical-protein
MQNKTITRILALSIITATFPSYNVSAVPPTASDHSATAASGSIGATVGLAISIGLPKENKNSPGNPGGPGGNPGNQGGPGGNPGNPSGGAGNPGGPGGNPGNPGRGNSGGGNPGR
>NC_010803.1|WP_012466787.1|2084610_2085603_-|NAD-dependent-epimerase/dehydratase-family-protein
MLKRVLLIGASGFVGTRLIETIGEKRCINIDKQNSSRYNNITLIHDIRNDGIDVAISHQPSSIVLLAAEHRDDVSPISLYYDVNVQGTKNVLDAMDHKGIKSIIFTSSVAVYGLNKKISDETHQADPFNHYGKSKWEAEEVLREWYQKDPENRSLSIIRPTVIFGEANRGNVYNLLKQIALGKFLMIGKGENKKSMAYVGNVVVFIKYLIENDKPGYRVYNYVDKPDFNMNELVHQVRHDLGQDGKMIRIPEWLGMLGGYGFDIAAKLSGKKLPISSVRVKKFCATTQFSADKLDKSGFIRPYTIEEGLERTLRYEFLEKNDDKHVFYTE
>NC_010803.1|WP_012466788.1|2085858_2087013_-|hypothetical-protein
MKKYIYFYDLNEKLLARYPAKISQEILSTHQDAEFVYLYSERYEKKGNPDKLPEGSKVVYLPTLSMTKIQKLFKTHPPALFITIGMRLPDILMLSFFNRHQVPTCMVQHGLFIKHLERIPLHLVIGQKLIKFTQYLIYSYKISRVLKKSFLKTLYELYLYFIKGSHKIPQLKHINSSLILAKTAFIFDDNWKKYYFITYGYTEEQFYKIGNPDFLILKQLKSAVQENAVCYICQSLVEDGRYLRSDFMCYIKEIEENLADDIKVYFKMHPRSRMELYEELNTDKINFTQEFPNCKFYLGHYSSLLAVAHDISQVIIWNLKGHQTPAEYVKYADMISNDWEEVRSFIRIKQQDNTTKDFDASYMEDSFNPYYHIAQFINQKATDF
>NC_010803.1|WP_012466789.1|2087014_2087779_-|2,4-dihydroxyhept-2-ene-1,7-dioic-acid-aldolase
MKNTRLKGQLKNNEQTLGSWVTIGHPAVVEVLSNANFDWLTIDIEHNNIDPAMLTTLIATIQSKNIAALVRVSKNEEVPIKHAMDAGADGVIVPMVNSREDAEKAVEYVKYPPRGKRGVGLSRAQNYGIGFESYKQWLQAYSVIIAQIEHIDGVRNIEQIIEVPDIDAIIIGPYDLSGSLGYPGNYSREDVREALIRVEQVCRERNFPMGFHVVPPDVEEVAIRRAAGYSFIAFSTDFLLMGDTATKLVNHLRK
>NC_010803.1|WP_012466790.1|2087775_2088447_-|cyclase-family-protein
MIFLSHHYASDTPTYGDRDKFKVAANSTIAGGGTANSSSWVFTNNHIGTHIDTPYHFNRNGMQTLDYPADFWYFNRVEIIDIPCNAARIIGPEAVAGCIIDPGTEMLLIRTGYELVRQEDKYWNDNPGLAPELADYLRSNFSKMRVIGFDFISITSWKHRQLGRESHKAFLVPGPGRIPILAIEDMALQAVHESIEWALVSPLRTEEGNGCPVTVFAKLTSDS
>NC_010803.1|WP_049754361.1|2088451_2089096_-|acylneuraminate-cytidylyltransferase-family-protein
MKGHSERVPNKNLRPVAGKPCFHWIIESLERSPYIGEIVINTDSDEIAESAKKNFQVTILERPDYLLGDMVSIQPLIEYDLSMTEGDYYLQTHSTNPLVTTETINNSIKTFFNQKEHDALFTVTPIKTRFYRADGSGVNHDPRHLIRTQDLDPIFEENSCLYIFSKKTNEQIRNRLGANPMMYPMDHLEAVDIDDMHDLLWAEFLLNQRLTRKL
>NC_010803.1|WP_012466792.1|2089141_2090425_-|right-handed-parallel-beta-helix-repeat-containing-protein
MKSGLRSIFLILWCGLLPAKNGSAYAAFNTFSRVSDLNSLRQLSEQMVFVLGYSEPGDGGGGWFRWEPNIMEEPDGSMRIRPHSFKQGCFARVTDGAGLNVKWFGAKGDGKHNDTEAIQSAIEWASARQSFFQQSIAVRDLVLIPSGQFLVDSLELKSGVILQGAGQFSSVILHTGNSSRCIYNEKGHHNRWVGIRELTVIGSDNKGTYTEGIHLFEANYSSYINRITIRGFTQNIVLEDCWTFQLTRSHLFKAHRNNLTILNGTAMEISGNRIDGAGKSNIQISRSKRYRNTGILIRNNAIQQAQEYGLYCRDTNSLLLEGNFFEANNRNGGFAFVYIEGPQTSKHCLIHSTSNYFSGANKSAPNSVGIFLKGNVKSFSSNQDYFSGSMGYGIYSVDLQSKEFVISGTTFHSKSDLKLPSDIKIIN
>NC_010803.1|WP_012466793.1|2090428_2090881_-|YhcH/YjgK/YiaL-family-protein
MIVDTLQNIETYKNLSEDIYAGLKFLSELKPDIELGEYHINERVKAIVSEYETIEEFTRGYEAHKHVVDIQYPIKGLERVKWSNIVGMDVNISYDEKKDRTFFKNPFPQMTHVDIGNGVFAIMFPQDGHGPQHYVSQPEMIKKVTVKVSI
>NC_010803.1|WP_150081661.1|2090887_2091967_-|3-dehydroquinate-synthase
MGDIQMYNFKVTSIIHDYEVHFIDSLKQSIDSVLMEGDYIIIDNIVKDLYDEYLQDALDTHKFIGIDANEKTKSYQGVESVIEELIQNGFRKNHRLVAIGGGITQDVTAFISSIMYRGVNWIFYPTTMLAQGDSCIGSKTSINFGRFKNQVGGFYPPSYIYIFPPFKDTLKEKEIRSGMGEMLHYFIVSGKEDFDFYRDTFKAAFTEKDALSGIINKSLEIKKRYIEIDEFDKKERQVFNYGHTFGHAIESLTQYRIPHGIAVSYGMDMSNFVSVKMGLIPSEVRDEIREVTSYIWEGYPIDDIDIDTYINALSKDKKNVGMQLGLILNKGYGNIFKNLTDSDKTFREWIEEYFLNELK

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity
NC_010803_4	4.1\|1009970\|35\|NC_010803\|PILER-CR,CRISPRCasFinder,CRT	1009970-1010004	35	NC_010803.1	2154873-2154907	0	1.0

1. spacer 4.1|1009970|35|NC_010803|PILER-CR,CRISPRCasFinder,CRT matches to position: 2154873-2154907, mismatch: 0, identity: 1.0

ttgcaggtcttccgcctgcgagctgaatcatgtcc	CRISPR spacer
ttgcaggtcttccgcctgcgagctgaatcatgtcc	Protospacer
***********************************

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NC_010803_3	3.1\|583716\|25\|NC_010803\|CRISPRCasFinder	583716-583740	25	AP014454	Uncultured Mediterranean phage uvMED isolate uvMED-CGF-C15-MedDCM-OCT-S36-C141, * SEQUENCING IN PROGRESS *, 2 ordered pieces	15750-15774	3	0.88
NC_010803_3	3.1\|583716\|25\|NC_010803\|CRISPRCasFinder	583716-583740	25	KJ025957	Serratia phage PS2, complete genome	4517-4541	3	0.88
NC_010803_3	3.1\|583716\|25\|NC_010803\|CRISPRCasFinder	583716-583740	25	AP014469	Uncultured Mediterranean phage uvMED isolate uvMED-CGF-C15G-MedDCM-OCT-S46-C52, * SEQUENCING IN PROGRESS *, 4 ordered pieces	31180-31204	3	0.88
NC_010803_3	3.1\|583716\|25\|NC_010803\|CRISPRCasFinder	583716-583740	25	NC_029006	Clostridium phage phiCT19406C, complete genome	23916-23940	3	0.88
NC_010803_3	3.1\|583716\|25\|NC_010803\|CRISPRCasFinder	583716-583740	25	MN693939	Marine virus AFVG_250M815, complete genome	32877-32901	3	0.88
NC_010803_3	3.1\|583716\|25\|NC_010803\|CRISPRCasFinder	583716-583740	25	MK496783	Capybara microvirus Cap3_SP_410, complete genome	1891-1915	3	0.88
NC_010803_3	3.1\|583716\|25\|NC_010803\|CRISPRCasFinder	583716-583740	25	MN694050	Marine virus AFVG_250M816, complete genome	32940-32964	3	0.88
NC_010803_3	3.1\|583716\|25\|NC_010803\|CRISPRCasFinder	583716-583740	25	NC_048030	Uncultured phage MedDCM-OCT-S08-C159 genomic sequence	3218-3242	4	0.84
NC_010803_3	3.1\|583716\|25\|NC_010803\|CRISPRCasFinder	583716-583740	25	MN095771	Serratia phage Muldoon, complete genome	4232-4256	4	0.84
NC_010803_7	7.1\|1402707\|26\|NC_010803\|CRISPRCasFinder	1402707-1402732	26	NZ_CP022542	Antarctobacter heliothermus strain SMS3 plasmid pSMS3-2, complete sequence	78646-78671	4	0.846
NC_010803_7	7.1\|1402707\|26\|NC_010803\|CRISPRCasFinder	1402707-1402732	26	KY006853	Erythrobacter phage vB_EliS_R6L, complete genome	41713-41738	4	0.846
NC_010803_7	7.1\|1402707\|26\|NC_010803\|CRISPRCasFinder	1402707-1402732	26	NZ_CP015733	Arthrobacter sp. U41 plasmid unnamed1, complete sequence	108788-108813	5	0.808
NC_010803_7	7.1\|1402707\|26\|NC_010803\|CRISPRCasFinder	1402707-1402732	26	KU064779	Pseudomonas phage PPPL-1, complete genome	26375-26400	5	0.808
NC_010803_7	7.1\|1402707\|26\|NC_010803\|CRISPRCasFinder	1402707-1402732	26	NZ_CP040096	Pantoea sp. SO10 plasmid unnamed1, complete sequence	97717-97742	6	0.769
NC_010803_2	2.5\|500073\|35\|NC_010803\|PILER-CR,CRISPRCasFinder,CRT	500073-500107	35	MH617123	Microviridae sp. isolate ctcd70, complete genome	3295-3329	7	0.8
NC_010803_2	2.5\|500073\|35\|NC_010803\|PILER-CR,CRISPRCasFinder,CRT	500073-500107	35	MH572425	Microviridae sp. isolate SD_MC_58, complete genome	3415-3449	7	0.8
NC_010803_2	2.61\|503800\|36\|NC_010803\|PILER-CR,CRISPRCasFinder,CRT	503800-503835	36	KT264757	Gokushovirus WZ-2015a isolate 09Rcn03, complete genome	2813-2848	7	0.806
NC_010803_2	2.61\|503800\|36\|NC_010803\|PILER-CR,CRISPRCasFinder,CRT	503800-503835	36	MG025518	Gokushovirus MK-2017 isolate AA_01, complete genome	3656-3691	7	0.806
NC_010803_2	2.96\|506145\|36\|NC_010803\|PILER-CR,CRISPRCasFinder,CRT	506145-506180	36	NC_031100	Bacillus phage Phrodo, complete genome	4618-4653	7	0.806
NC_010803_2	2.117\|507544\|36\|NC_010803\|PILER-CR,CRISPRCasFinder,CRT	507544-507579	36	NC_031100	Bacillus phage Phrodo, complete genome	4618-4653	7	0.806
NC_010803_2	2.5\|500073\|35\|NC_010803\|PILER-CR,CRISPRCasFinder,CRT	500073-500107	35	MH572295	Microviridae sp. isolate SD_SC_93, complete genome	3112-3146	8	0.771
NC_010803_2	2.5\|500073\|35\|NC_010803\|PILER-CR,CRISPRCasFinder,CRT	500073-500107	35	MH572296	Microviridae sp. isolate SD_SC_94, complete genome	3101-3135	8	0.771
NC_010803_2	2.5\|500073\|35\|NC_010803\|PILER-CR,CRISPRCasFinder,CRT	500073-500107	35	MH616790	Microviridae sp. isolate ctda718, complete genome	3505-3539	8	0.771
NC_010803_2	2.5\|500073\|35\|NC_010803\|PILER-CR,CRISPRCasFinder,CRT	500073-500107	35	MG945413	UNVERIFIED: Microviridae sp. isolate 4136-1801, complete genome	339-373	8	0.771
NC_010803_2	2.61\|503800\|36\|NC_010803\|PILER-CR,CRISPRCasFinder,CRT	503800-503835	36	MH992209	Apis mellifera associated microvirus 17 isolate INH_SP_257, complete genome	4174-4209	8	0.778
NC_010803_2	2.75\|504741\|36\|NC_010803\|PILER-CR,CRISPRCasFinder,CRT	504741-504776	36	NZ_CP022993	Paraburkholderia aromaticivorans strain BN5 plasmid pBN3, complete sequence	43393-43428	8	0.778
NC_010803_2	2.96\|506145\|36\|NC_010803\|PILER-CR,CRISPRCasFinder,CRT	506145-506180	36	NZ_CP041677	Lactobacillus reuteri strain LL7 plasmid unnamed, complete sequence	31323-31358	8	0.778
NC_010803_2	2.96\|506145\|36\|NC_010803\|PILER-CR,CRISPRCasFinder,CRT	506145-506180	36	NZ_CP021438	Bacillus thuringiensis strain C15 plasmid pBMB172, complete sequence	72209-72244	8	0.778
NC_010803_2	2.96\|506145\|36\|NC_010803\|PILER-CR,CRISPRCasFinder,CRT	506145-506180	36	LR215721	Staphylococcus phage Stab22 genome assembly, chromosome: I	122663-122698	8	0.778
NC_010803_2	2.96\|506145\|36\|NC_010803\|PILER-CR,CRISPRCasFinder,CRT	506145-506180	36	AP014352	Uncultured Mediterranean phage uvMED isolate uvMED-GF-U-MedDCM-OCT-S39-C33, * SEQUENCING IN PROGRESS *	29425-29460	8	0.778
NC_010803_2	2.117\|507544\|36\|NC_010803\|PILER-CR,CRISPRCasFinder,CRT	507544-507579	36	NZ_CP041677	Lactobacillus reuteri strain LL7 plasmid unnamed, complete sequence	31323-31358	8	0.778
NC_010803_2	2.117\|507544\|36\|NC_010803\|PILER-CR,CRISPRCasFinder,CRT	507544-507579	36	NZ_CP021438	Bacillus thuringiensis strain C15 plasmid pBMB172, complete sequence	72209-72244	8	0.778
NC_010803_2	2.117\|507544\|36\|NC_010803\|PILER-CR,CRISPRCasFinder,CRT	507544-507579	36	LR215721	Staphylococcus phage Stab22 genome assembly, chromosome: I	122663-122698	8	0.778
NC_010803_2	2.117\|507544\|36\|NC_010803\|PILER-CR,CRISPRCasFinder,CRT	507544-507579	36	AP014352	Uncultured Mediterranean phage uvMED isolate uvMED-GF-U-MedDCM-OCT-S39-C33, * SEQUENCING IN PROGRESS *	29425-29460	8	0.778
NC_010803_10	10.2\|2066032\|31\|NC_010803\|PILER-CR	2066032-2066062	31	GU943061	Uncultured phage MedDCM-OCT-S04-C846 genomic sequence	19699-19729	8	0.742
NC_010803_10	10.2\|2066032\|31\|NC_010803\|PILER-CR	2066032-2066062	31	GU943016	Uncultured phage MedDCM-OCT-S04-C1220 genomic sequence	3730-3760	8	0.742
NC_010803_10	10.2\|2066032\|31\|NC_010803\|PILER-CR	2066032-2066062	31	AP013881	Uncultured Mediterranean phage uvMED isolate uvMED-CGF-C1-MedDCM-OCT-S30-C177, * SEQUENCING IN PROGRESS *	3238-3268	8	0.742
NC_010803_10	10.2\|2066032\|31\|NC_010803\|PILER-CR	2066032-2066062	31	JX519267	Uncultured Mediterranean phage MEDS2 group fosmid MedDCM-OCT-S19-C1, complete sequence	31275-31305	8	0.742
NC_010803_10	10.2\|2066032\|31\|NC_010803\|PILER-CR	2066032-2066062	31	JX519264	Uncultured Mediterranean phage MEDS2 group fosmid MedDCM-OCT-S14-C1, complete sequence	19953-19983	8	0.742
NC_010803_10	10.2\|2066032\|31\|NC_010803\|PILER-CR	2066032-2066062	31	GU943057	Uncultured phage MedDCM-OCT-S04-C491 genomic sequence	2744-2774	8	0.742
NC_010803_10	10.2\|2066032\|31\|NC_010803\|PILER-CR	2066032-2066062	31	GU943058	Uncultured phage MedDCM-OCT-S04-C507 genomic sequence	29978-30008	8	0.742
NC_010803_10	10.2\|2066032\|31\|NC_010803\|PILER-CR	2066032-2066062	31	JX519266	Uncultured Mediterranean phage MEDS3 group fosmid MedDCM-OCT-S16-C5, complete sequence	16274-16304	8	0.742
NC_010803_10	10.2\|2066032\|31\|NC_010803\|PILER-CR	2066032-2066062	31	AP014473	Uncultured Mediterranean phage uvMED isolate uvMED-CGF-C1-MedDCM-OCT-S32-C86, * SEQUENCING IN PROGRESS *, 3 ordered pieces	26945-26975	8	0.742
NC_010803_2	2.5\|500073\|35\|NC_010803\|PILER-CR,CRISPRCasFinder,CRT	500073-500107	35	MH617758	Microviridae sp. isolate cteh020, complete genome	3068-3102	9	0.743
NC_010803_2	2.5\|500073\|35\|NC_010803\|PILER-CR,CRISPRCasFinder,CRT	500073-500107	35	MG945431	UNVERIFIED: Microviridae sp. isolate 4582-1801, complete genome	450-484	9	0.743
NC_010803_2	2.61\|503800\|36\|NC_010803\|PILER-CR,CRISPRCasFinder,CRT	503800-503835	36	MK496801	Capybara microvirus Cap3_SP_469, complete genome	2427-2462	9	0.75
NC_010803_2	2.61\|503800\|36\|NC_010803\|PILER-CR,CRISPRCasFinder,CRT	503800-503835	36	MG945543	UNVERIFIED: Microviridae sp. isolate 2478-180101, complete genome	4717-4752	9	0.75
NC_010803_2	2.87\|505542\|37\|NC_010803\|PILER-CR,CRISPRCasFinder,CRT	505542-505578	37	MN694571	Marine virus AFVG_250M1012, complete genome	5954-5990	9	0.757
NC_010803_2	2.96\|506145\|36\|NC_010803\|PILER-CR,CRISPRCasFinder,CRT	506145-506180	36	MG945264	UNVERIFIED: Microviridae sp. isolate 6208-1602, complete genome	5735-5770	9	0.75
NC_010803_2	2.117\|507544\|36\|NC_010803\|PILER-CR,CRISPRCasFinder,CRT	507544-507579	36	MG945264	UNVERIFIED: Microviridae sp. isolate 6208-1602, complete genome	5735-5770	9	0.75
NC_010803_2	2.61\|503800\|36\|NC_010803\|PILER-CR,CRISPRCasFinder,CRT	503800-503835	36	MG945801	UNVERIFIED: Microviridae sp. isolate 4621-1801, complete genome	5036-5071	10	0.722
NC_010803_2	2.61\|503800\|36\|NC_010803\|PILER-CR,CRISPRCasFinder,CRT	503800-503835	36	MG945333	UNVERIFIED: Microviridae sp. isolate 2135-1801, complete genome	4639-4674	10	0.722
NC_010803_2	2.96\|506145\|36\|NC_010803\|PILER-CR,CRISPRCasFinder,CRT	506145-506180	36	NZ_CP012989	Klebsiella pneumoniae strain KpN01 plasmid pKpN01-SIL, complete sequence	56241-56276	10	0.722
NC_010803_2	2.96\|506145\|36\|NC_010803\|PILER-CR,CRISPRCasFinder,CRT	506145-506180	36	NZ_CP025683	Klebsiella pneumoniae strain L5-2 plasmid pL5201, complete sequence	120487-120522	10	0.722
NC_010803_2	2.96\|506145\|36\|NC_010803\|PILER-CR,CRISPRCasFinder,CRT	506145-506180	36	NZ_CP012994	Klebsiella pneumoniae strain KpN06 plasmid pKpN06-SIL, complete sequence	53628-53663	10	0.722
NC_010803_2	2.96\|506145\|36\|NC_010803\|PILER-CR,CRISPRCasFinder,CRT	506145-506180	36	AP018698	Arthrobacter sp. MN05-02 plasmid plasmid1 DNA, complete genome	51349-51384	10	0.722
NC_010803_2	2.117\|507544\|36\|NC_010803\|PILER-CR,CRISPRCasFinder,CRT	507544-507579	36	NZ_CP012989	Klebsiella pneumoniae strain KpN01 plasmid pKpN01-SIL, complete sequence	56241-56276	10	0.722
NC_010803_2	2.117\|507544\|36\|NC_010803\|PILER-CR,CRISPRCasFinder,CRT	507544-507579	36	NZ_CP025683	Klebsiella pneumoniae strain L5-2 plasmid pL5201, complete sequence	120487-120522	10	0.722
NC_010803_2	2.117\|507544\|36\|NC_010803\|PILER-CR,CRISPRCasFinder,CRT	507544-507579	36	NZ_CP012994	Klebsiella pneumoniae strain KpN06 plasmid pKpN06-SIL, complete sequence	53628-53663	10	0.722
NC_010803_2	2.117\|507544\|36\|NC_010803\|PILER-CR,CRISPRCasFinder,CRT	507544-507579	36	AP018698	Arthrobacter sp. MN05-02 plasmid plasmid1 DNA, complete genome	51349-51384	10	0.722
NC_010803_4	4.18\|1011213\|36\|NC_010803\|PILER-CR,CRISPRCasFinder,CRT	1011213-1011248	36	NZ_CP027167	Pseudomonas aeruginosa strain AR_0356 plasmid unnamed3, complete sequence	151423-151458	11	0.694
NC_010803_4	4.18\|1011213\|36\|NC_010803\|PILER-CR,CRISPRCasFinder,CRT	1011213-1011248	36	NZ_CP029091	Pseudomonas aeruginosa strain AR441 plasmid unnamed1, complete sequence	128736-128771	11	0.694
NC_010803_4	4.18\|1011213\|36\|NC_010803\|PILER-CR,CRISPRCasFinder,CRT	1011213-1011248	36	MN583270	Pseudomonas aeruginosa strain NK546 plasmid pNK546b, complete sequence	86225-86260	11	0.694

1. spacer 3.1|583716|25|NC_010803|CRISPRCasFinder matches to AP014454 (Uncultured Mediterranean phage uvMED isolate uvMED-CGF-C15-MedDCM-OCT-S36-C141, *** SEQUENCING IN PROGRESS ***, 2 ordered pieces) position: , mismatch: 3, identity: 0.88

agcagaagaagcagcacctgcaaca	CRISPR spacer
agcagaagaagcagcaccatcaacg	Protospacer
******************  ****.

2. spacer 3.1|583716|25|NC_010803|CRISPRCasFinder matches to KJ025957 (Serratia phage PS2, complete genome) position: , mismatch: 3, identity: 0.88

agcagaagaagcagcacctgcaaca	CRISPR spacer
tgcagcagaagcagcagctgcaaca	Protospacer
 **** ********** ********

3. spacer 3.1|583716|25|NC_010803|CRISPRCasFinder matches to AP014469 (Uncultured Mediterranean phage uvMED isolate uvMED-CGF-C15G-MedDCM-OCT-S46-C52, *** SEQUENCING IN PROGRESS ***, 4 ordered pieces) position: , mismatch: 3, identity: 0.88

agcagaagaagcagcacctgcaaca	CRISPR spacer
agcagaagaagcagcaccatcaacg	Protospacer
******************  ****.

4. spacer 3.1|583716|25|NC_010803|CRISPRCasFinder matches to NC_029006 (Clostridium phage phiCT19406C, complete genome) position: , mismatch: 3, identity: 0.88

agcagaagaagcagcacctgcaaca	CRISPR spacer
agcagaagatgcagcacttgcaata	Protospacer
********* *******.*****.*

5. spacer 3.1|583716|25|NC_010803|CRISPRCasFinder matches to MN693939 (Marine virus AFVG_250M815, complete genome) position: , mismatch: 3, identity: 0.88

agcagaagaagcagcacctgcaaca	CRISPR spacer
agcagaagaagcagcagcggcaaga	Protospacer
**************** * **** *

6. spacer 3.1|583716|25|NC_010803|CRISPRCasFinder matches to MK496783 (Capybara microvirus Cap3_SP_410, complete genome) position: , mismatch: 3, identity: 0.88

agcagaagaagcagcacctgcaaca	CRISPR spacer
agcagaagaagcaacaccagcaaga	Protospacer
*************.**** **** *

7. spacer 3.1|583716|25|NC_010803|CRISPRCasFinder matches to MN694050 (Marine virus AFVG_250M816, complete genome) position: , mismatch: 3, identity: 0.88

agcagaagaagcagcacctgcaaca	CRISPR spacer
agcagaagaagcagcagcggcaaga	Protospacer
**************** * **** *

8. spacer 3.1|583716|25|NC_010803|CRISPRCasFinder matches to NC_048030 (Uncultured phage MedDCM-OCT-S08-C159 genomic sequence) position: , mismatch: 4, identity: 0.84

agcagaagaagcagcacctgcaaca	CRISPR spacer
agcagaagcagcagcaccttcaatg	Protospacer
******** ********** ***..

9. spacer 3.1|583716|25|NC_010803|CRISPRCasFinder matches to MN095771 (Serratia phage Muldoon, complete genome) position: , mismatch: 4, identity: 0.84

agcagaagaagcagcacctgcaaca	CRISPR spacer
ggcagcagaagcagcagctgcaacc	Protospacer
.**** ********** *******

10. spacer 7.1|1402707|26|NC_010803|CRISPRCasFinder matches to NZ_CP022542 (Antarctobacter heliothermus strain SMS3 plasmid pSMS3-2, complete sequence) position: , mismatch: 4, identity: 0.846

acgaactgaccaacagcggcacgttc	CRISPR spacer
atgtcctgaccaacagcggcacgatc	Protospacer
*.*  ****************** **

11. spacer 7.1|1402707|26|NC_010803|CRISPRCasFinder matches to KY006853 (Erythrobacter phage vB_EliS_R6L, complete genome) position: , mismatch: 4, identity: 0.846

acgaactgaccaacagcggcacgttc	CRISPR spacer
atgaactgaccaacagcgtcacggtg	Protospacer
*.**************** **** *

12. spacer 7.1|1402707|26|NC_010803|CRISPRCasFinder matches to NZ_CP015733 (Arthrobacter sp. U41 plasmid unnamed1, complete sequence) position: , mismatch: 5, identity: 0.808

acgaactgaccaacagcggcacgttc	CRISPR spacer
acgaacccaccaacagcggcacgcaa	Protospacer
******. ***************.

13. spacer 7.1|1402707|26|NC_010803|CRISPRCasFinder matches to KU064779 (Pseudomonas phage PPPL-1, complete genome) position: , mismatch: 5, identity: 0.808

acgaactgaccaacagcggcacgttc	CRISPR spacer
tcgaactgaccatcagcggctcgtat	Protospacer
 *********** ******* *** .

14. spacer 7.1|1402707|26|NC_010803|CRISPRCasFinder matches to NZ_CP040096 (Pantoea sp. SO10 plasmid unnamed1, complete sequence) position: , mismatch: 6, identity: 0.769

acgaactgaccaacagcggcacgttc	CRISPR spacer
cagaactgaccaacagcggcatgcgt	Protospacer
  *******************.*. .

15. spacer 2.5|500073|35|NC_010803|PILER-CR,CRISPRCasFinder,CRT matches to MH617123 (Microviridae sp. isolate ctcd70, complete genome) position: , mismatch: 7, identity: 0.8

ctatcttcactgtggtgaatacggtgataaaactg	CRISPR spacer
ttactttcactgtggtgaatacggagaaaaaacac	Protospacer
.**..******************* ** *****

16. spacer 2.5|500073|35|NC_010803|PILER-CR,CRISPRCasFinder,CRT matches to MH572425 (Microviridae sp. isolate SD_MC_58, complete genome) position: , mismatch: 7, identity: 0.8

ctatcttcactgtggtgaatacggtgataaaactg	CRISPR spacer
ctattatgcgtgtggtgaatatggcgataaaactg	Protospacer
****. *   ***********.**.**********

17. spacer 2.61|503800|36|NC_010803|PILER-CR,CRISPRCasFinder,CRT matches to KT264757 (Gokushovirus WZ-2015a isolate 09Rcn03, complete genome) position: , mismatch: 7, identity: 0.806

gtgtcagtcgtgcccattacatcaagtt--tcgtgggc	CRISPR spacer
gtgtcactcgtgcccattacatcaagacggtaatgg--	Protospacer
****** ******************* .  * .***

18. spacer 2.61|503800|36|NC_010803|PILER-CR,CRISPRCasFinder,CRT matches to MG025518 (Gokushovirus MK-2017 isolate AA_01, complete genome) position: , mismatch: 7, identity: 0.806

gtgtcagtcgtgcccattacatcaagt--ttcgtgggc	CRISPR spacer
gtgtcagtcggccccattacatcaagtaggtaatgg--	Protospacer
**********  ***************   * .***

19. spacer 2.96|506145|36|NC_010803|PILER-CR,CRISPRCasFinder,CRT matches to NC_031100 (Bacillus phage Phrodo, complete genome) position: , mismatch: 7, identity: 0.806

taaaagtagaagtagaagtagaagtagaagtaaatg	CRISPR spacer
cagaagtagaagtagaagtagaagtagaaccagaac	Protospacer
.*.************************** .*.*

20. spacer 2.117|507544|36|NC_010803|PILER-CR,CRISPRCasFinder,CRT matches to NC_031100 (Bacillus phage Phrodo, complete genome) position: , mismatch: 7, identity: 0.806

taaaagtagaagtagaagtagaagtagaagtaaatg	CRISPR spacer
cagaagtagaagtagaagtagaagtagaaccagaac	Protospacer
.*.************************** .*.*

21. spacer 2.5|500073|35|NC_010803|PILER-CR,CRISPRCasFinder,CRT matches to MH572295 (Microviridae sp. isolate SD_SC_93, complete genome) position: , mismatch: 8, identity: 0.771

ctatcttcactgtggtgaatacggtgataaaactg	CRISPR spacer
gttctttcactgtggcgaatacggtgaaaaaacct	Protospacer
 * ..**********.*********** *****.

22. spacer 2.5|500073|35|NC_010803|PILER-CR,CRISPRCasFinder,CRT matches to MH572296 (Microviridae sp. isolate SD_SC_94, complete genome) position: , mismatch: 8, identity: 0.771

ctatcttcactgtggtgaatacggtgataaaactg	CRISPR spacer
gttctttcactgtggagaatacggtgaaaaaacct	Protospacer
 * ..********** *********** *****.

23. spacer 2.5|500073|35|NC_010803|PILER-CR,CRISPRCasFinder,CRT matches to MH616790 (Microviridae sp. isolate ctda718, complete genome) position: , mismatch: 8, identity: 0.771

ctatcttcactgtggtgaatacggtgataaaactg	CRISPR spacer
gtacttcgcctgcggtgaatacggtgaaaaaactg	Protospacer
 **..*.  ***.************** *******

24. spacer 2.5|500073|35|NC_010803|PILER-CR,CRISPRCasFinder,CRT matches to MG945413 (UNVERIFIED: Microviridae sp. isolate 4136-1801, complete genome) position: , mismatch: 8, identity: 0.771

ctatcttcactgtggtgaatacggtgataaaactg	CRISPR spacer
gttttttgcctgtggtgaatatggtgataatactt	Protospacer
 * *.**  ************.******** ***

25. spacer 2.61|503800|36|NC_010803|PILER-CR,CRISPRCasFinder,CRT matches to MH992209 (Apis mellifera associated microvirus 17 isolate INH_SP_257, complete genome) position: , mismatch: 8, identity: 0.778

gtgtcagtcgtgcccattacatcaagtttcgtgggc-----	CRISPR spacer
gtgtcagtcgtgccagttacatcaa-----gtgggtaacgg	Protospacer
************** .*********     *****.

26. spacer 2.75|504741|36|NC_010803|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP022993 (Paraburkholderia aromaticivorans strain BN5 plasmid pBN3, complete sequence) position: , mismatch: 8, identity: 0.778

tccgacagcgggcctccaccctgcgacaaaccagtt	CRISPR spacer
tccgacagcgggcctcaacgctgcgaagaagctaat	Protospacer
**************** ** ****** .** * . *

27. spacer 2.96|506145|36|NC_010803|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP041677 (Lactobacillus reuteri strain LL7 plasmid unnamed, complete sequence) position: , mismatch: 8, identity: 0.778

taaaagtagaagtagaagtagaagtagaagtaaatg	CRISPR spacer
gagaagtagaagtagaagtagaagcagaaatagtac	Protospacer
 *.*********************.****.**.

28. spacer 2.96|506145|36|NC_010803|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP021438 (Bacillus thuringiensis strain C15 plasmid pBMB172, complete sequence) position: , mismatch: 8, identity: 0.778

taaaagtagaagtagaagtagaagtagaagtaaatg	CRISPR spacer
aattagtagaagtaggagtagaagtagaagggagag	Protospacer
 *  ***********.************** .*. *

29. spacer 2.96|506145|36|NC_010803|PILER-CR,CRISPRCasFinder,CRT matches to LR215721 (Staphylococcus phage Stab22 genome assembly, chromosome: I) position: , mismatch: 8, identity: 0.778

taaaagtagaagtagaagtagaagtagaagtaaatg	CRISPR spacer
ctgaagtagaagtagaagtagaagaagaaacagaag	Protospacer
. .********************* ****..*.* *

30. spacer 2.96|506145|36|NC_010803|PILER-CR,CRISPRCasFinder,CRT matches to AP014352 (Uncultured Mediterranean phage uvMED isolate uvMED-GF-U-MedDCM-OCT-S39-C33, *** SEQUENCING IN PROGRESS ***) position: , mismatch: 8, identity: 0.778

taaaagtagaagtagaagtagaagtagaagtaaatg	CRISPR spacer
aagcaccagaagtagaagtagaagaataagtaaaag	Protospacer
 *. * .***************** * ******* *

31. spacer 2.117|507544|36|NC_010803|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP041677 (Lactobacillus reuteri strain LL7 plasmid unnamed, complete sequence) position: , mismatch: 8, identity: 0.778

taaaagtagaagtagaagtagaagtagaagtaaatg	CRISPR spacer
gagaagtagaagtagaagtagaagcagaaatagtac	Protospacer
 *.*********************.****.**.

32. spacer 2.117|507544|36|NC_010803|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP021438 (Bacillus thuringiensis strain C15 plasmid pBMB172, complete sequence) position: , mismatch: 8, identity: 0.778

taaaagtagaagtagaagtagaagtagaagtaaatg	CRISPR spacer
aattagtagaagtaggagtagaagtagaagggagag	Protospacer
 *  ***********.************** .*. *

33. spacer 2.117|507544|36|NC_010803|PILER-CR,CRISPRCasFinder,CRT matches to LR215721 (Staphylococcus phage Stab22 genome assembly, chromosome: I) position: , mismatch: 8, identity: 0.778

taaaagtagaagtagaagtagaagtagaagtaaatg	CRISPR spacer
ctgaagtagaagtagaagtagaagaagaaacagaag	Protospacer
. .********************* ****..*.* *

34. spacer 2.117|507544|36|NC_010803|PILER-CR,CRISPRCasFinder,CRT matches to AP014352 (Uncultured Mediterranean phage uvMED isolate uvMED-GF-U-MedDCM-OCT-S39-C33, *** SEQUENCING IN PROGRESS ***) position: , mismatch: 8, identity: 0.778

taaaagtagaagtagaagtagaagtagaagtaaatg	CRISPR spacer
aagcaccagaagtagaagtagaagaataagtaaaag	Protospacer
 *. * .***************** * ******* *

35. spacer 10.2|2066032|31|NC_010803|PILER-CR matches to GU943061 (Uncultured phage MedDCM-OCT-S04-C846 genomic sequence) position: , mismatch: 8, identity: 0.742

tgctaaccgctaaccacccacagcccacaat	CRISPR spacer
gtctaaccgctaaccacccacaagccatgtc	Protospacer
  ********************. ***.. .

36. spacer 10.2|2066032|31|NC_010803|PILER-CR matches to GU943016 (Uncultured phage MedDCM-OCT-S04-C1220 genomic sequence) position: , mismatch: 8, identity: 0.742

tgctaaccgctaaccacccacagcccacaat	CRISPR spacer
gtctaaccgctaaccacccacaagccatgtc	Protospacer
  ********************. ***.. .

37. spacer 10.2|2066032|31|NC_010803|PILER-CR matches to AP013881 (Uncultured Mediterranean phage uvMED isolate uvMED-CGF-C1-MedDCM-OCT-S30-C177, *** SEQUENCING IN PROGRESS ***) position: , mismatch: 8, identity: 0.742

tgctaaccgctaaccacccacagcccacaat	CRISPR spacer
gtctaaccgctaaccacccacaagccatgtc	Protospacer
  ********************. ***.. .

38. spacer 10.2|2066032|31|NC_010803|PILER-CR matches to JX519267 (Uncultured Mediterranean phage MEDS2 group fosmid MedDCM-OCT-S19-C1, complete sequence) position: , mismatch: 8, identity: 0.742

tgctaaccgctaaccacccacagcccacaat	CRISPR spacer
gtctaaccgctaaccacccacaagccatgtc	Protospacer
  ********************. ***.. .

39. spacer 10.2|2066032|31|NC_010803|PILER-CR matches to JX519264 (Uncultured Mediterranean phage MEDS2 group fosmid MedDCM-OCT-S14-C1, complete sequence) position: , mismatch: 8, identity: 0.742

tgctaaccgctaaccacccacagcccacaat	CRISPR spacer
gtctaaccgctaaccacccacaagccatgtc	Protospacer
  ********************. ***.. .

40. spacer 10.2|2066032|31|NC_010803|PILER-CR matches to GU943057 (Uncultured phage MedDCM-OCT-S04-C491 genomic sequence) position: , mismatch: 8, identity: 0.742

tgctaaccgctaaccacccacagcccacaat	CRISPR spacer
gtctaaccgctaaccacccacaagccatgtc	Protospacer
  ********************. ***.. .

41. spacer 10.2|2066032|31|NC_010803|PILER-CR matches to GU943058 (Uncultured phage MedDCM-OCT-S04-C507 genomic sequence) position: , mismatch: 8, identity: 0.742

tgctaaccgctaaccacccacagcccacaat	CRISPR spacer
gtctaaccgctaaccacccacaagccatgtc	Protospacer
  ********************. ***.. .

42. spacer 10.2|2066032|31|NC_010803|PILER-CR matches to JX519266 (Uncultured Mediterranean phage MEDS3 group fosmid MedDCM-OCT-S16-C5, complete sequence) position: , mismatch: 8, identity: 0.742

tgctaaccgctaaccacccacagcccacaat	CRISPR spacer
gtctaaccgctaaccacccacaagccatgtc	Protospacer
  ********************. ***.. .

43. spacer 10.2|2066032|31|NC_010803|PILER-CR matches to AP014473 (Uncultured Mediterranean phage uvMED isolate uvMED-CGF-C1-MedDCM-OCT-S32-C86, *** SEQUENCING IN PROGRESS ***, 3 ordered pieces) position: , mismatch: 8, identity: 0.742

tgctaaccgctaaccacccacagcccacaat	CRISPR spacer
gtctaaccgctaaccacccacaagccatgtc	Protospacer
  ********************. ***.. .

44. spacer 2.5|500073|35|NC_010803|PILER-CR,CRISPRCasFinder,CRT matches to MH617758 (Microviridae sp. isolate cteh020, complete genome) position: , mismatch: 9, identity: 0.743

ctatcttcactgtggtgaatacggtgataaaactg	CRISPR spacer
tttttttcattgtggtgaatacggtgctaattttt	Protospacer
.* *.****.**************** ***  .*

45. spacer 2.5|500073|35|NC_010803|PILER-CR,CRISPRCasFinder,CRT matches to MG945431 (UNVERIFIED: Microviridae sp. isolate 4582-1801, complete genome) position: , mismatch: 9, identity: 0.743

ctatcttcactgtggtgaatacggtgataaaactg	CRISPR spacer
gtttttcgcttgtggtgaatatggtgataagactg	Protospacer
 * *.*.  .***********.********.****

46. spacer 2.61|503800|36|NC_010803|PILER-CR,CRISPRCasFinder,CRT matches to MK496801 (Capybara microvirus Cap3_SP_469, complete genome) position: , mismatch: 9, identity: 0.75

gtgtcagtcgtgcccattacatcaagtttcgtgggc	CRISPR spacer
gtgtcactcgtacccattacatcaagtggaaatggg	Protospacer
****** ****.***************   .  **

47. spacer 2.61|503800|36|NC_010803|PILER-CR,CRISPRCasFinder,CRT matches to MG945543 (UNVERIFIED: Microviridae sp. isolate 2478-180101, complete genome) position: , mismatch: 9, identity: 0.75

gtgtcagtcgtgcccattacatcaagt-----ttcgtgggc	CRISPR spacer
ctgtcagtcgtgcccaatatatcaagtagatattgg-----	Protospacer
 *************** **.*******     ** *

48. spacer 2.87|505542|37|NC_010803|PILER-CR,CRISPRCasFinder,CRT matches to MN694571 (Marine virus AFVG_250M1012, complete genome) position: , mismatch: 9, identity: 0.757

tagtaaaaatttgatgggttcgggtacgccagatgca	CRISPR spacer
cggtaaaaatttgatgcgttcgggttcgcgtgaataa	Protospacer
..************** ******** ***  **   *

49. spacer 2.96|506145|36|NC_010803|PILER-CR,CRISPRCasFinder,CRT matches to MG945264 (UNVERIFIED: Microviridae sp. isolate 6208-1602, complete genome) position: , mismatch: 9, identity: 0.75

taaaagtagaagtagaagtagaagtagaagtaaatg	CRISPR spacer
tagacgtagaagtagaagtagaagtaccggaagaga	Protospacer
**.* *********************  .* *.* .

50. spacer 2.117|507544|36|NC_010803|PILER-CR,CRISPRCasFinder,CRT matches to MG945264 (UNVERIFIED: Microviridae sp. isolate 6208-1602, complete genome) position: , mismatch: 9, identity: 0.75

taaaagtagaagtagaagtagaagtagaagtaaatg	CRISPR spacer
tagacgtagaagtagaagtagaagtaccggaagaga	Protospacer
**.* *********************  .* *.* .

51. spacer 2.61|503800|36|NC_010803|PILER-CR,CRISPRCasFinder,CRT matches to MG945801 (UNVERIFIED: Microviridae sp. isolate 4621-1801, complete genome) position: , mismatch: 10, identity: 0.722

gtgtcagtcgtgcccattacatcaagtttcgtgggc	CRISPR spacer
gtgtcagtggggcccattacatcaagaggtgtaatg	Protospacer
******** * ***************   .**..

52. spacer 2.61|503800|36|NC_010803|PILER-CR,CRISPRCasFinder,CRT matches to MG945333 (UNVERIFIED: Microviridae sp. isolate 2135-1801, complete genome) position: , mismatch: 10, identity: 0.722

gtgtcagtcgtgcccattacatcaagtttcgtgggc	CRISPR spacer
gtgtcactcgtacccattacatcaagaagagtaatg	Protospacer
****** ****.**************    **..

53. spacer 2.96|506145|36|NC_010803|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP012989 (Klebsiella pneumoniae strain KpN01 plasmid pKpN01-SIL, complete sequence) position: , mismatch: 10, identity: 0.722

------taaaagtagaagtagaagtagaagtagaagtaaatg	CRISPR spacer
tgttagaaaaagtagaagtagaagtagaagtttaac------	Protospacer
       ************************  **

54. spacer 2.96|506145|36|NC_010803|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP025683 (Klebsiella pneumoniae strain L5-2 plasmid pL5201, complete sequence) position: , mismatch: 10, identity: 0.722

------taaaagtagaagtagaagtagaagtagaagtaaatg	CRISPR spacer
tgttagaaaaagtagaagtagaagtagaagtttaac------	Protospacer
       ************************  **

55. spacer 2.96|506145|36|NC_010803|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP012994 (Klebsiella pneumoniae strain KpN06 plasmid pKpN06-SIL, complete sequence) position: , mismatch: 10, identity: 0.722

------taaaagtagaagtagaagtagaagtagaagtaaatg	CRISPR spacer
tgttagaaaaagtagaagtagaagtagaagtttaac------	Protospacer
       ************************  **

56. spacer 2.96|506145|36|NC_010803|PILER-CR,CRISPRCasFinder,CRT matches to AP018698 (Arthrobacter sp. MN05-02 plasmid plasmid1 DNA, complete genome) position: , mismatch: 10, identity: 0.722

taaaagtagaagtagaagtagaagtagaagtaaatg	CRISPR spacer
tcgcagtagaagtagaagtaggagtggaagtcgggt	Protospacer
* . *****************.***.***** ..

57. spacer 2.117|507544|36|NC_010803|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP012989 (Klebsiella pneumoniae strain KpN01 plasmid pKpN01-SIL, complete sequence) position: , mismatch: 10, identity: 0.722

------taaaagtagaagtagaagtagaagtagaagtaaatg	CRISPR spacer
tgttagaaaaagtagaagtagaagtagaagtttaac------	Protospacer
       ************************  **

58. spacer 2.117|507544|36|NC_010803|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP025683 (Klebsiella pneumoniae strain L5-2 plasmid pL5201, complete sequence) position: , mismatch: 10, identity: 0.722

------taaaagtagaagtagaagtagaagtagaagtaaatg	CRISPR spacer
tgttagaaaaagtagaagtagaagtagaagtttaac------	Protospacer
       ************************  **

59. spacer 2.117|507544|36|NC_010803|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP012994 (Klebsiella pneumoniae strain KpN06 plasmid pKpN06-SIL, complete sequence) position: , mismatch: 10, identity: 0.722

------taaaagtagaagtagaagtagaagtagaagtaaatg	CRISPR spacer
tgttagaaaaagtagaagtagaagtagaagtttaac------	Protospacer
       ************************  **

60. spacer 2.117|507544|36|NC_010803|PILER-CR,CRISPRCasFinder,CRT matches to AP018698 (Arthrobacter sp. MN05-02 plasmid plasmid1 DNA, complete genome) position: , mismatch: 10, identity: 0.722

taaaagtagaagtagaagtagaagtagaagtaaatg	CRISPR spacer
tcgcagtagaagtagaagtaggagtggaagtcgggt	Protospacer
* . *****************.***.***** ..

61. spacer 4.18|1011213|36|NC_010803|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP027167 (Pseudomonas aeruginosa strain AR_0356 plasmid unnamed3, complete sequence) position: , mismatch: 11, identity: 0.694

aacaaatggagctgggtcgacaacccgtagtgcagc	CRISPR spacer
gcgtagaggagctgggccgacaacccgcagtgcctg	Protospacer
.   *. *********.**********.*****

62. spacer 4.18|1011213|36|NC_010803|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP029091 (Pseudomonas aeruginosa strain AR441 plasmid unnamed1, complete sequence) position: , mismatch: 11, identity: 0.694

aacaaatggagctgggtcgacaacccgtagtgcagc	CRISPR spacer
gcgtagaggagctgggccgacaacccgcagtgcctg	Protospacer
.   *. *********.**********.*****

63. spacer 4.18|1011213|36|NC_010803|PILER-CR,CRISPRCasFinder,CRT matches to MN583270 (Pseudomonas aeruginosa strain NK546 plasmid pNK546b, complete sequence) position: , mismatch: 11, identity: 0.694

aacaaatggagctgggtcgacaacccgtagtgcagc	CRISPR spacer
gcgtagaggagctgggccgacaacccgcagtgcctg	Protospacer
.   *. *********.**********.*****

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

1948514 : 1959063

Escherichia_phage(42.86%)

tRNA

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_012466685.1\|1948514_1951769_-\|tRNA	isoleucine--tRNA ligase	A0A2I2L3Y0	Orpheovirus	3.2e-162	33.1
WP_012466686.1\|1951927_1952143_-	hypothetical protein	NA	NA	NA	NA
WP_012466687.1\|1952281_1953736_-	mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase	A0A1V0SH58	Hokovirus	5.4e-53	29.0
WP_012466688.1\|1953782_1954775_-	UDP-glucose 4-epimerase GalE	A0A2K9L5H6	Tupanvirus	5.5e-41	35.3
WP_012466689.1\|1954824_1955268_-	HEPN domain-containing protein	NA	NA	NA	NA
WP_012466690.1\|1955562_1956612_-	dTDP-glucose 4,6-dehydratase	A0A1D7XFE8	Escherichia_phage	1.6e-86	50.5
WP_041465997.1\|1956626_1957505_-	dTDP-4-dehydrorhamnose reductase	A0A1D8EQE2	Escherichia_phage	2.0e-39	39.0
WP_012466692.1\|1957519_1958098_-	dTDP-4-dehydrorhamnose 3,5-epimerase	A0A1D8EQH2	Escherichia_phage	3.5e-40	50.6
WP_012466693.1\|1958166_1959063_-	glucose-1-phosphate thymidylyltransferase RfbA	I7I009	Enterobacteria_phage	3.4e-106	61.5

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. NC_010803

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

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Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

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Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection