CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NC_011296	Thermodesulfovibrio yellowstonii DSM 11347, complete sequence	5 crisprs	DEDDh,csx1,cas10,csm2gr11,csm3gr7,csm4gr5,csm5gr7,cas6,csa3,Cas14b_CAS-V-F,PD-DExK,cas2,cas1,cas3,Cas9_archaeal,cas3HD,cmr1gr7,cmr6gr7,cmr4gr7,cmr5gr11,cmr3gr5,csa5gr11,cas7,cas5,cas4,cas8b2	0	14	4	0

Results visualization

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CRISPR-Cas detection and classification

Crispr_ID: NC_011296_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_011296_1

62006-62269

TypeIII

Consensus_repeat	Method
TCGCAATCCCTTTTAAATGAGGTCTTGTTTTCCAAC	CRISPRCasFinder
TCGCAATCCCTTTTAAATGAGGTCTTGTTTTCCAAC	CRT
TCGCAATCCCTTTTAAATGAGGTCTTGTTTTCCAACAG	PILER-CR

3 spacers

csx1,cas10,csm2gr11,csm3gr7,csm4gr5,csm5gr7,cas6

The CRISPR arrays of NC_011296_1

>merge|NC_011296|1|62006-62269|CRISPRCasFinder,CRT,PILER-CR
TAAATGTCCCTTTTAAATGAGGTCTTGTTTTCCAACATAAAGAACCCTTTGAGCCGAAATGGCTCAGAGATCTCTCGCAATCCCTTTTAAATGAGGTCTTGTTTTCCAACAGAAAAAAAATTAGTAGTTCTATCTTAGAATCATTTAAGTCGCAATCCCTTTTAAATGAGGTCTTGTTTTCCAACTGATCTGGATAGAGAATTGGAGATAAAGGGAATAAAGGAAGTCGCAATCCCTTTTAAATGAGGTCTTGTTTTCCAACGG

>NC_011296|1|1|62006-62267|CRISPRCasFinder
TAAATGTCCCTTTTAAATGAGGTCTTGTTTTCCAAC	ATAAAGAACCCTTTGAGCCGAAATGGCTCAGAGATCTC
TCGCAATCCCTTTTAAATGAGGTCTTGTTTTCCAAC	AGAAAAAAAATTAGTAGTTCTATCTTAGAATCATTTAAG
TCGCAATCCCTTTTAAATGAGGTCTTGTTTTCCAAC	TGATCTGGATAGAGAATTGGAGATAAAGGGAATAAAGGAAG
TCGCAATCCCTTTTAAATGAGGTCTTGTTTTCCAAC

>NC_011296|1|1|62006-62267|CRT
TAAATGTCCCTTTTAAATGAGGTCTTGTTTTCCAAC	ATAAAGAACCCTTTGAGCCGAAATGGCTCAGAGATCTC
TCGCAATCCCTTTTAAATGAGGTCTTGTTTTCCAAC	AGAAAAAAAATTAGTAGTTCTATCTTAGAATCATTTAAG
TCGCAATCCCTTTTAAATGAGGTCTTGTTTTCCAAC	TGATCTGGATAGAGAATTGGAGATAAAGGGAATAAAGGAAG
TCGCAATCCCTTTTAAATGAGGTCTTGTTTTCCAAC

>NC_011296|1|1|62080-62269|PILER-CR
TCGCAATCCCTTTTAAATGAGGTCTTGTTTTCCAACAG	AAAAAAAATTAGTAGTTCTATCTTAGAATCATTTAAG
TCGCAATCCCTTTTAAATGAGGTCTTGTTTTCCAACTG	ATCTGGATAGAGAATTGGAGATAAAGGGAATAAAGGAAG
TCGCAATCCCTTTTAAATGAGGTCTTGTTTTCCAACGG

Protein	Signature genes	Signature genes Name	Protein_function
NC_011296.1\|WP_012546045.1\|59108_59867_+\|conjugative-transfer:-surface-exclusion	unknown	unknown	gnl\|CDD\|377558
NC_011296.1\|WP_012545938.1\|56269_57106_-\|M23-family-metallopeptidase	unknown	unknown	gnl\|CDD\|366703
NC_011296.1\|WP_012546328.1\|55403_55808_-\|LysR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|224916
NC_011296.1\|WP_012545181.1\|62668_64978_+\|type-III-A-CRISPR-associated-protein-Cas10/Csm1	cas10	cd09680_cas10_CAS-III	gnl\|CDD\|274209
NC_011296.1\|WP_012545976.1\|69136_70288_+\|DUF1887-family-protein	csx1	pfam09002_csx1_CAS-III	gnl\|CDD\|312526
NC_011296.1\|WP_012546597.1\|53592_54306_-\|ABC-transporter-permease-subunit	unknown	unknown	gnl\|CDD\|227008
NC_011296.1\|WP_012545335.1\|57225_58032_+\|ribonuclease-H-like-domain-containing-protein	unknown	unknown	gnl\|CDD\|379215
NC_011296.1\|WP_012545230.1\|54309_55116_-\|extracellular-solute-binding-protein	unknown	unknown	gnl\|CDD\|225544
NC_011296.1\|WP_012545107.1\|59997_60714_+\|hypothetical-protein	unknown	unknown	unknown
NC_011296.1\|WP_012546537.1\|66217_67201_+\|type-III-A-CRISPR-associated-RAMP-protein-Csm4	csm4gr5	cd09663_csm4gr5_CAS-III-A	gnl\|CDD\|273866
NC_011296.1\|WP_012545354.1\|65419_66205_+\|type-III-A-CRISPR-associated-RAMP-protein-Csm3	csm3gr7	COG1337_csm3gr7_CAS-III-D	gnl\|CDD\|274212
NC_011296.1\|WP_012546625.1\|64970_65420_+\|type-III-A-CRISPR-associated-protein-Csm2	csm2gr11	pfam03750_csm2gr11_CAS-III-A	gnl\|CDD\|367635
NC_011296.1\|WP_012544962.1\|55913_56270_-\|polymer-forming-cytoskeletal-protein	unknown	unknown	gnl\|CDD\|377376
NC_011296.1\|WP_012546824.1\|67205_68357_+\|type-III-A-CRISPR-associated-RAMP-protein-Csm5	csm5gr7	cd09662_csm5gr7_CAS-III-A	gnl\|CDD\|187793
NC_011296.1\|WP_012545465.1\|60749_61820_-\|TIGR02584-family-CRISPR-associated-protein	csx1	cd09686_csx1_CAS-III	gnl\|CDD\|274214
NC_011296.1\|WP_012546237.1\|57997_58882_+\|site-specific-tyrosine-recombinase-XerD	unknown	unknown	gnl\|CDD\|234713
NC_011296.1\|WP_012546514.1\|70290_70539_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|370583
NC_011296.1\|WP_012545325.1\|68360_69107_+\|hypothetical-protein	csx1	pfam09670_csx1_CAS-III	gnl\|CDD\|187878
NC_011296.1\|WP_012545643.1\|70541_71480_+\|CRISPR-system-precrRNA-processing-endoribonuclease-RAMP-protein-Cas6	cas6	mkCas0066_cas6_CAS-I:CAS-III	gnl\|CDD\|187890
NC_011296.1\|WP_012546735.1\|71532_73782_+\|DNA-internalization-related-competence-protein-ComEC/Rec2	unknown	unknown	gnl\|CDD\|273036

Protein	Function_ID	Function_description	E-value
NC_011296.1\|WP_012546045.1\|59108_59867_+\|conjugative-transfer:-surface-exclusion	gnl\|CDD\|377558	pfam05818, TraT, Enterobacterial TraT complement resistance protein. The traT gene is one of the F factor transfer genes and encodes an outer membrane protein which is involved in interactions between an Escherichia coli and its surroundings.	4.43869e-78
NC_011296.1\|WP_012546328.1\|55403_55808_-\|LysR-family-transcriptional-regulator	gnl\|CDD\|224916	COG2005, ModE, N-terminal domain of molybdenum-binding protein [General function prediction only].	1.01549e-29
NC_011296.1\|WP_012545181.1\|62668_64978_+\|type-III-A-CRISPR-associated-protein-Cas10/Csm1	gnl\|CDD\|274209	TIGR02578, CRISPR-associated_protein_Cas10/Csm1, CRISPR-associated protein Cas10/Csm1, subtype III-A/MTUBE. The family is designated Csm2, for CRISPR/Cas Subtype Mtube Protein 2. A typical example is TM1811 from Thermotoga maritima. CRISPR are Clustered Regularly Interspaced Short Palindromic Repeats. This protein family belongs to a conserved gene cluster regularly found near CRISPR repeats.	0
NC_011296.1\|WP_012545976.1\|69136_70288_+\|DUF1887-family-protein	gnl\|CDD\|312526	pfam09002, DUF1887, Domain of unknown function (DUF1887). This domain is found in a set of hypothetical bacterial proteins.	1.844e-44
NC_011296.1\|WP_012545325.1\|68360_69107_+\|hypothetical-protein	gnl\|CDD\|187878	cd09747, Csx1_III-U, CRISPR/Cas system-associated protein Csx1. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Protein of this family often fused to HTH domain; Some proteins could have an additional fusion with RecB-family nuclease domain; Core domain appears to have a Rossmann-like fold; loosely associated with CRISPR/Cas systems; also known as Cas02710 family.	8.39772e-08
NC_011296.1\|WP_012546625.1\|64970_65420_+\|type-III-A-CRISPR-associated-protein-Csm2	gnl\|CDD\|367635	pfam03750, Csm2_III-A, Csm2 Type III-A. Clusters of short DNA repeats with non-homologous spacers, which are found at regular intervals in the genomes of phylogenetically distinct prokaryotic species, comprise a family with recognisable features. This family is known as CRISPR (short for Clustered Regularly Interspaced Short Palindromic Repeats). A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-associated) proteins. This entry represents Csm2 Type III-A, a family of Cas proteins also known as TM1810/Csm2.	3.30629e-36
NC_011296.1\|WP_012545335.1\|57225_58032_+\|ribonuclease-H-like-domain-containing-protein	gnl\|CDD\|379215	pfam13482, RNase_H_2, RNase_H superfamily.	5.8189e-34
NC_011296.1\|WP_012546597.1\|53592_54306_-\|ABC-transporter-permease-subunit	gnl\|CDD\|227008	COG4662, TupA, ABC-type tungstate transport system, periplasmic component [Coenzyme metabolism].	1.11524e-62
NC_011296.1\|WP_012545938.1\|56269_57106_-\|M23-family-metallopeptidase	gnl\|CDD\|366703	pfam01551, Peptidase_M23, Peptidase family M23. Members of this family are zinc metallopeptidases with a range of specificities. The peptidase family M23 is included in this family, these are Gly-Gly endopeptidases. Peptidase family M23 are also endopeptidases. This family also includes some bacterial lipoproteins for which no proteolytic activity has been demonstrated. This family also includes leukocyte cell-derived chemotaxin 2 (LECT2) proteins. LECT2 is a liver-specific protein which is thought to be linked to hepatocyte growth although the exact function of this protein is unknown.	5.74955e-48
NC_011296.1\|WP_012546537.1\|66217_67201_+\|type-III-A-CRISPR-associated-RAMP-protein-Csm4	gnl\|CDD\|273866	TIGR01903, Hypothetical_protein., CRISPR type III-A/MTUBE-associated RAMP protein Csm4. CRISPR is a term for Clustered Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR associated) proteins. Members of this cas gene family are found in the mtube subtype of CRISPR/cas locus and designated Csm4, for CRISPR/cas Subtype Mtube, protein 4.	5.22834e-50
NC_011296.1\|WP_012545354.1\|65419_66205_+\|type-III-A-CRISPR-associated-RAMP-protein-Csm3	gnl\|CDD\|274212	TIGR02582, CRISPR_type_III-associated_RAMP_protein_Csm3, CRISPR type III-A/MTUBE-associated RAMP protein Csm3. Members of this CRISPR-associated (cas) gene family are found in the mtube subtype of CRISPR/cas locus and designated Csm3, for CRISPR/cas Subtype Mtube, protein 3.	2.88928e-89
NC_011296.1\|WP_012544962.1\|55913_56270_-\|polymer-forming-cytoskeletal-protein	gnl\|CDD\|377376	pfam04519, Bactofilin, Polymer-forming cytoskeletal. This is a family of bactofilins, a functionally diverse class of cytoskeletal, polymer-forming, proteins that is widely conserved among bacteria. In the example species C. crescentus, two bactofilins assemble into a membrane-associated laminar structure that shows cell-cycle-dependent polar localization and acts as a platform for the recruitment of a cell wall biosynthetic enzyme involved in polar morphogenesis. Bactofilins display distinct subcellular distributions and dynamics in different bacterial species, suggesting that they are versatile structural elements that have adopted a range of different cellular functions.	1.52743e-21
NC_011296.1\|WP_012546824.1\|67205_68357_+\|type-III-A-CRISPR-associated-RAMP-protein-Csm5	gnl\|CDD\|187793	cd09662, Csm5_III-A, CRISPR/Cas system-associated RAMP superfamily protein Csm5. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; RAMP superfamily protein.	1.95766e-20
NC_011296.1\|WP_012545465.1\|60749_61820_-\|TIGR02584-family-CRISPR-associated-protein	gnl\|CDD\|274214	TIGR02584, hypothetical_protein_NE0113, CRISPR-associated protein, NE0113 family. Members of this minor CRISPR-associated (Cas) protein family are found in cas gene clusters in Vibrio vulnificus YJ016, Nitrosomonas europaea ATCC 19718, Mannheimia succiniciproducens MBEL55E, and Verrucomicrobium spinosum.	2.43501e-116
NC_011296.1\|WP_012546237.1\|57997_58882_+\|site-specific-tyrosine-recombinase-XerD	gnl\|CDD\|234713	PRK00283, xerD, tyrosine recombinase.	9.81344e-136
NC_011296.1\|WP_012546514.1\|70290_70539_+\|hypothetical-protein	gnl\|CDD\|370583	pfam09620, Cas_csx3, CRISPR-associated protein (Cas_csx3). This entry is encoded in CRISPR-associated (cas) gene clusters, near CRISPR repeats, in the genomes of several different thermophiles: Archaeoglobus fulgidus (archaeal), Aquifex aeolicus (Aquificae), Dictyoglomus thermophilum (Dictyoglomi), and a thermophilic Synechococcus (Cyanobacteria). It is not yet assigned to a specific CRISPR/cas subtype (hence the x designation csx3).	5.27383e-06
NC_011296.1\|WP_012545230.1\|54309_55116_-\|extracellular-solute-binding-protein	gnl\|CDD\|225544	COG2998, TupA, tungsten ABC transporter substrate-binding protein [Coenzyme metabolism].	3.4946e-112
NC_011296.1\|WP_012545643.1\|70541_71480_+\|CRISPR-system-precrRNA-processing-endoribonuclease-RAMP-protein-Cas6	gnl\|CDD\|187890	cd09760, Cas6_III, CRISPR/Cas system-associated RAMP superfamily protein Cas6. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas6 is an endoribonuclease that generates crRNAs, predicted subunit of Cascade complex.	6.6478e-11
NC_011296.1\|WP_012546735.1\|71532_73782_+\|DNA-internalization-related-competence-protein-ComEC/Rec2	gnl\|CDD\|273036	TIGR00361, Recombination_protein_2, DNA internalization-related competence protein ComEC/Rec2. Apparant orthologs are found in 5 species so far (Haemophilus influenzae, Escherichia coli, Bacillus subtilis, Neisseria gonorrhoeae, Streptococcus pneumoniae), of which all but E. coli are model systems for the study of competence for natural transformation. This protein is a predicted multiple membrane-spanning protein likely to be involved in DNA internalization. In a large number of bacterial species not known to exhibit competence, this protein is replaced by a half-length N-terminal homolog of unknown function, modelled by the related model ComEC_N-term. The role for this protein in species that are not naturally transformable is unknown. [Cellular processes, DNA transformation].	6.14366e-52

>NC_011296.1|WP_012545465.1|60749_61820_-|TIGR02584-family-CRISPR-associated-protein
MKKHILLCVIGMTPQIITETIYALAKKKINIEELHVITTLDGKRKLTETLINKGILSQLIHEYNLPSINFSEKSIYLIKNFKNKPLSDIRTPVDNESAGEIICKVVHKLTARKNTILHCSLAGGRKTMGFYLGAALQMYGRKDDKLYHVLVNEEFENLPEFFYPPAKSKEIIIKTKDGQFLKKSTSEVKIELAELPFLRLKELIDFSGKTFRELIDSTQIKFDNFKKIPYLGFIPAENILKIGDRKIKLSYNLWEFYTKLALQKKRACKHPQKLFCMNCTDCFLPMKGNTSLLTLFNQREENIRMKISKINSIIKNSLIAYYGKDNINFFLINSVGSHGSKKYGIFLDKLKIVRED
>NC_011296.1|WP_012545107.1|59997_60714_+|hypothetical-protein
MELLSKNNSNIFRLENEQEIELDEIHKKWVQSGINQITSSIENSDKQDFMKFLFPENGKYSLMLITNPVVDPIRNIVGQATFTAVAIKKFFDSKVELVDMYSERISGGLFNMDSKRIDSLKSFFKKNSEKENTCSFATFILYVKKPDLVKRQDGRWQIKLSNKLIGSCPFIQREKTFEKTIYLIMPYSFQPDLSKIDDNKYINITPSIQPTNVILDIQLLNEFFEWLRKEMKFHNIQI
>NC_011296.1|WP_012546045.1|59108_59867_+|conjugative-transfer:-surface-exclusion
MREWTNPKKKVFILLILTLFLLQTTGCGQMINAIEHSDMQVKLKMTDTIFLDPVVKAKNRTIYVAVNNTSDMQEVDTTMLQNLITSRLAAKGYQVVNDPTQAGYIIQTNILYMDYYRQTGTKEGALEGALVGGGSGALIGQSRDTSIALGLIGALVGGIGGAILGKALKVETYAGVVDVQIQEKTDKPVTGQIVTNAQQGSSTTIQTKQEISSNYQIYRTKIACTAQQTNIDKVEAARAIAEKIANQIGGMF
>NC_011296.1|WP_012546237.1|57997_58882_+|site-specific-tyrosine-recombinase-XerD
MEQKEILKKFLNYLLTEKALSINTVKSYENDLKNFLKWLTEQNILVLNCKKDDIVQYLLNLKEKAYSSTSIARILSSLKQFFRFMIFDSIINHDPTEGLKSPKLWLRLPKALEIDEVKRLLSVMLESKYYLRDIAMLELMYASGLRVSELVRLKLSDINFEAGFIRVKGKGDKERVVPIAQRSIDKIKNYLVKLRPVLLKKKASEYVFLNNRGQPMTRQRFWQNIKAIGRIAGVNVTPHMIRHSFATHLLEGGADLRSLQKMLGHSDISTTQIYTKVSMDRLRKEYLKHHPRAK
>NC_011296.1|WP_012545335.1|57225_58032_+|ribonuclease-H-like-domain-containing-protein
MIKNTFLLLDGIGEKREKRLWREGILTWEDFFHCKEVLDIDFERKRIYDDFLHRAFEALSCKDCSFFSKNLKKREHWRLFQEFINNAVCLDIETNGLTHEKGGYVTVVGLYSIGGYKSLIRGENLTEENLQRTLNEYKYLITFYGTIFDIPFLKKEFPNLQIEHIPHFDLFFAGKRLGIQGGLKKLETMFLIERQEELKGLNGYDAIKLWKAYLNGSTDSLELLISYNRADTENLFHLGRIFYEMLRSQVGIEEFTGNGTKRDSQKVS
>NC_011296.1|WP_012545938.1|56269_57106_-|M23-family-metallopeptidase
MYKLKKLILKIFSPITIMLIPHGRTKVYGVKIPFLLIFLFICCWLAFNIYVFSIAVNTIEYYQMKQNLSSIMNKFNELKSTIIALKHAEAEFNKIFSLRSKKEILESINFHPSGDIDIEELKKHAEKAINTVSEIKNFLSEQQDIYKSTPLGWPVKGEITSPFGKREHPKYGYEEFHTGIDVSVPPGTEIKATADGIVVFSGYQGRNGNVVMIKHGYGFTTVYAHNKQNLVNVGQKVKRGDIIAISGNTGSTTGPHLHYEVWKNNSPVSPLSYLKEDF
>NC_011296.1|WP_012544962.1|55913_56270_-|polymer-forming-cytoskeletal-protein
MFIKKQQKMETVIGAETFIKGEITSNSSIKIDGTVEGIIKADWISVGDSGKITGNITCRGIVVGGNVNGTINASEIITITHKGSVTGEIFTVKISIEEGGKFEGKSCIQLSSLFPDEK
>NC_011296.1|WP_012546328.1|55403_55808_-|LysR-family-transcriptional-regulator
MKKRGRKALKDPHHFCVTGGGKHEGYELKGKIWIDGNEGTFLGYGRIALLEKIKQYGSISKAAKSINMSYRQAWRLISSMNRQAGKPFVETQIGGKNGGGTKLTEAGEKAIEQFWRIHKKFKKFLSKEIKNFEI
>NC_011296.1|WP_012545230.1|54309_55116_-|extracellular-solute-binding-protein
MKRFLITILFLLIFVGRAFAEQNVILLATTTSVENSGLLSYILPAFEKKTGIKVKVIARGTGAAIEMGKRGDADLVFVHAKELELEAVKQGFFINRHDVCYNDFIVVGPKNDPAEIKGFKKASEAFKKIAITHSFFVSRADKSGTYMKELNLWKLAGINPKGQNWYLEAGQGMEKTLRIANEKSAYTLTDRGTWLAMKGRLELSLLFEGDPLLFNQYGVMAVNPQRHKHVRYKEAIQLINWLISKEGQSLIGSFKDKNGNQLFIPNAK
>NC_011296.1|WP_012546597.1|53592_54306_-|ABC-transporter-permease-subunit
MNFILESFNQATNLILNLDRELLQIIFLSLKVSGIALFTATVIGLPLGAFVGLKRFVGRGLLITTLNTFMGLPPVVVGLFLYLMLSRSGPLGFLSLLYTPTAMIIAQTILAFPIVAGLTHSAVVRVAPIIKLASRSLGATSFQTTLTVIKEARYGIMSAVIAALGRVMAEVGAILIVGGNIAGYTRVMTTTIAMETDKGNFELAMALGIVLLLISLMINFFMFLIQKRGVKEDFQWD
>NC_011296.1|WP_012545181.1|62668_64978_+|type-III-A-CRISPR-associated-protein-Cas10/Csm1
MITELEVVAKGGLLYNIGRVALRAEGNFNEENFVEKGREWIEKHLKNDDSALKIAKSLQEKDELFFLWKEAHSLACKNEDIKYFTPNPIISPFYKIRNPNNLNETLNKIPYYQLQSEKPQIAIYNKPIINHENYRRLIEKFKKDLQSTKPPYGINLLTMLMEKHLSNIPLGSPFDDVSMFRHCVLVSAISGCLYLYLKEKRRDKDFSVASIVDCLSSEKPFLLVGGDLSGIQKFIYTITSKGALRALKGRSFYIELLIEHIVNEIIDNLNLTRCNIVFSAGGNFCIVSPNTDNAVSELDKLKSRIETFLFNEFKGELQLHLEYIAFGEESFKNSASVSDGLGEKLEKSKKTGWQKRLKDILKPESPHENCLTTQCDVCFREDVSLVSLQRGDEALQVCEPCYFQYKLGEELLEISEGISPVIYRLSEQPQGDYVKIEKFYYCFRRSRDEKLENLADKIYRINNFNAENYNKPNNIFLPLGIYKKRGLKELTDAVSDFGINRLAVLRMDVDNLGKIFGSAIAEQERTFARISEISNRLNQFFKYHLNYIAEGKEIDSLDIAERGVKNKGRNLMIIYSGGDDVFILGHWLDVIETAFDIRRYFELFTGNRFLTISGGIAINQDSYPVYQYARDAEELERLAKRDNKKDSLALLDDRKVGWNSFDEVIERIRLFKKFLKTESNGFVIDEQKLPKTFFYGLFSLAKVFRKEGILVLPKAAYLISRAKFNNCADEDVLSIKEVIMNSNEKEWEITELATLVTLMLMRKGGRDHE
>NC_011296.1|WP_012546625.1|64970_65420_+|type-III-A-CRISPR-associated-protein-Csm2
MNDFRKQQGQQKYHGQNQQTQINLRELKRDISGYSKLEDLPAEKVIDISEKLGAHLKIIGLKTSQIRKFLDGVRKLDNLFVRGKNFDKEQVILLKPKLAYAAGRQKEIKPLMEILGPAIDSGAKSYKSFKKLIALIEGIIAYHRYYGGE
>NC_011296.1|WP_012545354.1|65419_66205_+|type-III-A-CRISPR-associated-RAMP-protein-Csm3
MNRNLIGKIQMKGKIKCLTGLHIGAAKENIEIGAIDASVVRDPVTREPYIPGSSLKGKLRALLEKSLSIKLGIIGTENRINIGTKTNPVYIHVCTDADKAYKCPICRIFGSTGQGGGKNYPSRLIVRDAYLTTESVEELSQIDTGLQFTEWKFENAIDRVTSAANPRQLERVPRGAEFEFEFIYNVEDKETVLEDLESITLAIELLKLDSLGGHGSRGYGKIQINFEDIKCFSLEYLKSGQGEVKSITDLSKKEELLSVFK
>NC_011296.1|WP_012546537.1|66217_67201_+|type-III-A-CRISPR-associated-RAMP-protein-Csm4
MVIYSYKLHFKTPVHFGETGIYLENVEERFSSDSLFSALINTVSNYYGEKESEKWIDKFENNPPFLLSSLFIYNSDKYFLPKPLDDSFISREIRKKIGKELKKIRWLEAKDFLLWQKRQITKVEDIEKIKINSERYSDAFKREIRPRVTIDRITSQSSIYFCGSIKFQREAGLYGMVAFRDTDFIERFRIVMKLLGQTGIGGERTYGYGMFELKDFKPIDGVLKKLMESDTEGFTLLSLYTPSNTEIDDLVQKIVAYEIKIKKGWITSGRTALPLKRKSLGFIKEGSVFSKPLRGCLVDVTPENAPPDILKHKVYRYGYAFTVPLKE
>NC_011296.1|WP_012546824.1|67205_68357_+|type-III-A-CRISPR-associated-RAMP-protein-Csm5
MALFEKAEVKIVTKSPVHIGGVEQKKTRFEFIIHGNYLYPISEDRLAEFLSKENLIFDYCAQLENKANLFNLADFLRSKAFILNESLLLKLSSGKRIYLNHNASLIQDYRPYIRDGFGMPYIPGTSIKGVIRTAILYNLLKELKESSYEDFEVNFERRIVEDIEQKKNKRDFSAWLNKEYFEGFKLLGKEKSPYTDWLKMLKISDAYPDGEIQTSIIPINILKREENWKYKEEYSGKKTTIWTECIPENVTFRFEVLWERSFLSEFKKQHYRFKMPENLNATFECINRWAQDLINFEKEFLATNAMKKWYENNVCNFRIGFGSGMISTTILMLLSESLRKKIRNYAGLDRGETIAPKSRRVFQRDSLLTPLGWCLITVDGTRH
>NC_011296.1|WP_012545325.1|68360_69107_+|hypothetical-protein
MTSHFKPTKKNILAFMGIFILVFSILLFLSECFHDVIYGFSEKIHSLTILVEYLKTSIELTFIFIAVKNWKPIYRWISGKREFRGTGDEFTFPKDKVKAIIIPVSRTEQPEWIIRHLEPKYVAFLYTGERKNHVIELINLFSKKIHFAHTLKEIEQGKDMLSDPDNPNEAKEIVKKFIEGFIAQGIKEENIFVDTTGGKVPMSIGAFQAAEEMGVSSIYIVGKGNNGNIKEPTLREQGYPIFLSRKNE
>NC_011296.1|WP_012545976.1|69136_70288_+|DUF1887-family-protein
MKHIHVCLISEQTIPNILGIFYFKPEEVLFITTEQMLKREKTEAIVNTLKRLGLNIPFFEIVVREDSIYDCHRKIAQWMEKHEEDNFTVNLTCGTKIMSIATYEIFKDYGSKMIYIPIPKNEFFEVYPLKKLSEPQPLPLRLGVIEYLTAYSLRVINEAKLNRYKEESEKRKALTNWIVTNYNSIEGLLSEFYKVLQKSRNVSSFDLTIEFPISNELQRDFLKAVGFNISGRTISKRLSRSEIRYLTGGWLEEYVFNSLNSIKGRGIDDVVMNVEIENIQGNKNEFDVMFTKDNALYFVECKSLSPEDEITKSSLYKIGALQKEFGLRVQSFFVTTSPHIIKDGQIRQSVRARAEQFKTEIIKPDEIVNFETIIRKKLKIMEE
>NC_011296.1|WP_012546514.1|70290_70539_+|hypothetical-protein
MSEIVIDMRQIYEGDQAKIKDIPDYIKKALELAGEGNEIILTGQGPIWLYLKIAHALHGKAVKLIYRSPVTGDIVIFDHSPY
>NC_011296.1|WP_012545643.1|70541_71480_+|CRISPR-system-precrRNA-processing-endoribonuclease-RAMP-protein-Cas6
MKIHYQKYIFYIKAIEPLYLPYYKGSTFRGGFGNAFRKVACPLRVINCDKCLLKQKCIYAYVFETPPPEGSTILNMNKYEKIPHPFVIEPPEWRQQYFPEGQTLSFNLILIGSAIDYIPYFIYTFEQLGGIGIGKGRGKYILSEVKIDGITVYKKGILKKSISKIMEIPSKFETTDSVENLTLKIITPLRIRYQRKFVTELDFHILVRNLIRRISLLGYFHCGEQLPDFTVQEVIRHAETINTVNSNLRWHDWERYSSRQEIKMKLGGVVGEIVYRGNIAPFIPYLKAGEILHVGKNTSFGLGKYEIILDEA
>NC_011296.1|WP_012546735.1|71532_73782_+|DNA-internalization-related-competence-protein-ComEC/Rec2
MPYILSSVFGILSGVIFIYFPILSIFLASLPIAVCLLKKKYSVAFVCLILSLVGVFYGNLREGKNFDNKETTLSFKGYVVSTKDNTHLVKTIEGKRLRVYSREKLEENRLYTVECKSVNEHKNPYVFSKQDFCYATKLFDEGKLNQGIFERVQNNINKKLKQKLNEPAASVMIAMTTGQRNEIPEEIKDDFQKTGLIHLLSISGAHFSLLFTVFFIVFRILTRFIPYKWLVLMTLYIKPSQLSIILCFPFLLFYYLLIEPNYPSTRAFIMALFFMLGVLTERKSIWIITVSLACLFILVIDPSSTKDLSFQLSFLATVAIGFATDIYKNFKNKIQNKVLSYLLLSLLISFSASLITAPIVIYKFHYLSLISPVANLTAGFVIGMFLFPLNVIFVFIYLITGIYPLPEIVNTIANFSFKLMHLLASFSFSSLSIPPIPLGSVILFYFGIFLSIFACYGLKGWFKKLSFMVSCLLIFSSVLTSLVLDNLQRNFIKITFLDVGQAESAVVETPEAVFLVDTGKTGFEAVQYLKAKGYRQLQALIITHEQKDHAGGFLNIIEKFNVKEIWDNGYIKYKIPMNVKHLERGDILKAGNCIFTLLHPYKGFYTSSLSNDSNELSLVFSLKCKTKTFLFTSDTGIEVLKSIPATYLKADILKIPHHGSKRSFYKEFYETVLPQICIISVGKNNTYGHPHTEVLEYLKDKCKIYRTDIHGAIQIREKANGEIEVKTFEETKFKPYRELENLKKLFILW

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Crispr_ID: NC_011296_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_011296_2

632030-633918

TypeIII

Consensus_repeat	Method
GTCGCAATCCCTTTTAAATGAGGTCTTGTTTCCTAC	PILER-CR
GTAGGAAACAAGACCTCATTTAAAAGGGATTGCGAC	CRISPRCasFinder
GTAGGAAACAAGACCTCATTTAAAAGGGATTGCGAC	CRT

26 spacers

cas6,csm5gr7,csm4gr5,csm3gr7,csm2gr11,cas10,csx1,cas2,cas1

The CRISPR arrays of NC_011296_2

>merge|NC_011296|2|632030-633918|PILER-CR,CRISPRCasFinder,CRT
GTAGGAAACAAGACCTCATTTAAAAGGGATTGCGACTTCATTGCTTATTTTATCAATTTCATCTTCAACTTGTTTGTAGGAAACAAGACCTCATTTAAAAGGGATTGCGACTTCTCTTTTAAATAGATATCGTGAGGGCAAATTTTGTAGGAAACAAGACCTCATTTAAAAGGGATTGCGACCTAAAGTATCCTTTATCTCTTGTATAAGAGATTGGTAGGAAACAAGACCTCATTTAAAAGGGATTGCGACATAATTTGATAGTTCTAAATCTTGTCCTATTATCTCAGTAGGAAACAAGACCTCATTTAAAAGGGATTGCGACCGCTAGTTGGTATAACTACATGATAAAAATCAGTTGTAGGAAACAAGACCTCATTTAAAAGGGATTGCGACTTTTTCTTTTTTACAATATTCTCTACTTCTTTGTAGGAAACAAGACCTCATTTAAAAGGGATTGCGACATCAAAAACCACTATTTCCTTTGCTTCTTTTTGTTGGTAGGAAACAAGACCTCATTTAAAAGGGATTGCGACTTTGACTATGTCATTTGTTTGACATGGGAAAGTTGAGTAGGAAACAAGACCTCATTTAAAAGGGATTGCGACCAATTTCAATTAATTCTTTCATTTTCCCCTCCGATGTAGGAAACAAGACCTCATTTAAAAGGGATTGCGACTTCAAGTCCCATCTCCTTGTAAATTTTCTTCTTCTCGTAGGAAACAAGACCTCATTTAAAAGGGATTGCGACTTTAAGGCGGCGATAAGTGTCTCTTGCTTTTGTCCTGTAGGAAACAAGACCTCATTTAAAAGGGATTGCGACCCATTTTTACCTCCCTTTTTGGTTTTGTAAAAAGTAGGAAACAAGACCTCATTTAAAAGGGATTGCGACTAATTGGTTTAATGATACCCCGATATGGGTCCAATGTAGGAAACAAGACCTCATTTAAAAGGGATTGCGACATTTTGTTCCTCTTCCTTTGCCCACTCCCAATCTGTAGGAAACAAGACCTCATTTAAAAGGGATTGCGACATAACGTATCATATCAAATATTACAAGGATTTTCCCTGTAGGAAACAAGACCTCATTTAAAAGGGATTGCGACTTAATCCATAAGTTATATTGTCTTCTTTAAAATAAGTAGGAAACAAGACCTCATTTAAAAGGGATTGCGACATCCATTTTTGAGTGCATTTTCAAAGACCTGAAGTCGTAGGAAACAAGACCTCATTTAAAAGGGATTGCGACCAAGCACTATAGCAGCACCACCGCACACAAACCCAAGTAGGAAACAAGACCTCATTTAAAAGGGATTGCGACTGCAGTAAACGCAATAGGCGGCAGAGTTATGTCAGGTAGGAAACAAGACCTCATTTAAAAGGGATTGCGACGGCTTTTCCTTTGCAGCATCAATTGCTGCAACTTGTAGGAAACAAGACCTCATTTAAAAGGGATTGCGACGATATGAAACCAGAGGATACTTATTCATTATGTTGTGTAGGAAACAAGACCTCATTTAAAAGGGATTGCGACATAAAACCTCCTATATGTTTCATTTCTTCTTTAACTGTAGGAAACAAGACCTCATTTAAAAGGGATTGCGACCACACATAGTAACATAAGTTGTAACGGCAACATGTAGGAAACAAGACCTCATTTAAAAGGGATTGCGACTCAAAGAATCCCAGAAGGGTGCACCAACTATCTGTGTAGGAAACAAGACCTCATTTAAAAGGGATTGCGACATGAATCATTGTATTGTAGTCCTGATAGCAGATTCTGTAGGAAACAAGACCTCATTTAAAAGGGATTGCGACTTAAAATACTCAGTTGTGGTTGTCCTGCTCTTTATGTAGGAAACAAGACCTCATTTAAAAGGGATTGCGAG

>NC_011296|2|2|632030-633918|PILER-CR
GTAGGAAACAAGACCTCATTTAAAAGGGATTGCGAC	TTCATTGCTTATTTTATCAATTTCATCTTCAACTTGTTT
GTAGGAAACAAGACCTCATTTAAAAGGGATTGCGAC	TTCTCTTTTAAATAGATATCGTGAGGGCAAATTTT
GTAGGAAACAAGACCTCATTTAAAAGGGATTGCGAC	CTAAAGTATCCTTTATCTCTTGTATAAGAGATTG
GTAGGAAACAAGACCTCATTTAAAAGGGATTGCGAC	ATAATTTGATAGTTCTAAATCTTGTCCTATTATCTCA
GTAGGAAACAAGACCTCATTTAAAAGGGATTGCGAC	CGCTAGTTGGTATAACTACATGATAAAAATCAGTT
GTAGGAAACAAGACCTCATTTAAAAGGGATTGCGAC	TTTTTCTTTTTTACAATATTCTCTACTTCTTT
GTAGGAAACAAGACCTCATTTAAAAGGGATTGCGAC	ATCAAAAACCACTATTTCCTTTGCTTCTTTTTGTTG
GTAGGAAACAAGACCTCATTTAAAAGGGATTGCGAC	TTTGACTATGTCATTTGTTTGACATGGGAAAGTTGA
GTAGGAAACAAGACCTCATTTAAAAGGGATTGCGAC	CAATTTCAATTAATTCTTTCATTTTCCCCTCCGAT
GTAGGAAACAAGACCTCATTTAAAAGGGATTGCGAC	TTCAAGTCCCATCTCCTTGTAAATTTTCTTCTTCTC
GTAGGAAACAAGACCTCATTTAAAAGGGATTGCGAC	TTTAAGGCGGCGATAAGTGTCTCTTGCTTTTGTCCT
GTAGGAAACAAGACCTCATTTAAAAGGGATTGCGAC	CCATTTTTACCTCCCTTTTTGGTTTTGTAAAAA
GTAGGAAACAAGACCTCATTTAAAAGGGATTGCGAC	TAATTGGTTTAATGATACCCCGATATGGGTCCAAT
GTAGGAAACAAGACCTCATTTAAAAGGGATTGCGAC	ATTTTGTTCCTCTTCCTTTGCCCACTCCCAATCT
GTAGGAAACAAGACCTCATTTAAAAGGGATTGCGAC	ATAACGTATCATATCAAATATTACAAGGATTTTCCCT
GTAGGAAACAAGACCTCATTTAAAAGGGATTGCGAC	TTAATCCATAAGTTATATTGTCTTCTTTAAAATAA
GTAGGAAACAAGACCTCATTTAAAAGGGATTGCGAC	ATCCATTTTTGAGTGCATTTTCAAAGACCTGAAGTC
GTAGGAAACAAGACCTCATTTAAAAGGGATTGCGAC	CAAGCACTATAGCAGCACCACCGCACACAAACCCAA
GTAGGAAACAAGACCTCATTTAAAAGGGATTGCGAC	TGCAGTAAACGCAATAGGCGGCAGAGTTATGTCAG
GTAGGAAACAAGACCTCATTTAAAAGGGATTGCGAC	GGCTTTTCCTTTGCAGCATCAATTGCTGCAACTT
GTAGGAAACAAGACCTCATTTAAAAGGGATTGCGAC	GATATGAAACCAGAGGATACTTATTCATTATGTTGT
GTAGGAAACAAGACCTCATTTAAAAGGGATTGCGAC	ATAAAACCTCCTATATGTTTCATTTCTTCTTTAACT
GTAGGAAACAAGACCTCATTTAAAAGGGATTGCGAC	CACACATAGTAACATAAGTTGTAACGGCAACAT
GTAGGAAACAAGACCTCATTTAAAAGGGATTGCGAC	TCAAAGAATCCCAGAAGGGTGCACCAACTATCTGT
GTAGGAAACAAGACCTCATTTAAAAGGGATTGCGAC	ATGAATCATTGTATTGTAGTCCTGATAGCAGATTCT
GTAGGAAACAAGACCTCATTTAAAAGGGATTGCGAC	TTAAAATACTCAGTTGTGGTTGTCCTGCTCTTTAT
GTAGGAAACAAGACCTCATTTAAAAGGGATTGCGAG

>NC_011296|2|2|632030-633918|CRISPRCasFinder
GTAGGAAACAAGACCTCATTTAAAAGGGATTGCGAC	TTCATTGCTTATTTTATCAATTTCATCTTCAACTTGTTT
GTAGGAAACAAGACCTCATTTAAAAGGGATTGCGAC	TTCTCTTTTAAATAGATATCGTGAGGGCAAATTTT
GTAGGAAACAAGACCTCATTTAAAAGGGATTGCGAC	CTAAAGTATCCTTTATCTCTTGTATAAGAGATTG
GTAGGAAACAAGACCTCATTTAAAAGGGATTGCGAC	ATAATTTGATAGTTCTAAATCTTGTCCTATTATCTCA
GTAGGAAACAAGACCTCATTTAAAAGGGATTGCGAC	CGCTAGTTGGTATAACTACATGATAAAAATCAGTT
GTAGGAAACAAGACCTCATTTAAAAGGGATTGCGAC	TTTTTCTTTTTTACAATATTCTCTACTTCTTT
GTAGGAAACAAGACCTCATTTAAAAGGGATTGCGAC	ATCAAAAACCACTATTTCCTTTGCTTCTTTTTGTTG
GTAGGAAACAAGACCTCATTTAAAAGGGATTGCGAC	TTTGACTATGTCATTTGTTTGACATGGGAAAGTTGA
GTAGGAAACAAGACCTCATTTAAAAGGGATTGCGAC	CAATTTCAATTAATTCTTTCATTTTCCCCTCCGAT
GTAGGAAACAAGACCTCATTTAAAAGGGATTGCGAC	TTCAAGTCCCATCTCCTTGTAAATTTTCTTCTTCTC
GTAGGAAACAAGACCTCATTTAAAAGGGATTGCGAC	TTTAAGGCGGCGATAAGTGTCTCTTGCTTTTGTCCT
GTAGGAAACAAGACCTCATTTAAAAGGGATTGCGAC	CCATTTTTACCTCCCTTTTTGGTTTTGTAAAAA
GTAGGAAACAAGACCTCATTTAAAAGGGATTGCGAC	TAATTGGTTTAATGATACCCCGATATGGGTCCAAT
GTAGGAAACAAGACCTCATTTAAAAGGGATTGCGAC	ATTTTGTTCCTCTTCCTTTGCCCACTCCCAATCT
GTAGGAAACAAGACCTCATTTAAAAGGGATTGCGAC	ATAACGTATCATATCAAATATTACAAGGATTTTCCCT
GTAGGAAACAAGACCTCATTTAAAAGGGATTGCGAC	TTAATCCATAAGTTATATTGTCTTCTTTAAAATAA
GTAGGAAACAAGACCTCATTTAAAAGGGATTGCGAC	ATCCATTTTTGAGTGCATTTTCAAAGACCTGAAGTC
GTAGGAAACAAGACCTCATTTAAAAGGGATTGCGAC	CAAGCACTATAGCAGCACCACCGCACACAAACCCAA
GTAGGAAACAAGACCTCATTTAAAAGGGATTGCGAC	TGCAGTAAACGCAATAGGCGGCAGAGTTATGTCAG
GTAGGAAACAAGACCTCATTTAAAAGGGATTGCGAC	GGCTTTTCCTTTGCAGCATCAATTGCTGCAACTT
GTAGGAAACAAGACCTCATTTAAAAGGGATTGCGAC	GATATGAAACCAGAGGATACTTATTCATTATGTTGT
GTAGGAAACAAGACCTCATTTAAAAGGGATTGCGAC	ATAAAACCTCCTATATGTTTCATTTCTTCTTTAACT
GTAGGAAACAAGACCTCATTTAAAAGGGATTGCGAC	CACACATAGTAACATAAGTTGTAACGGCAACAT
GTAGGAAACAAGACCTCATTTAAAAGGGATTGCGAC	TCAAAGAATCCCAGAAGGGTGCACCAACTATCTGT
GTAGGAAACAAGACCTCATTTAAAAGGGATTGCGAC	ATGAATCATTGTATTGTAGTCCTGATAGCAGATTCT
GTAGGAAACAAGACCTCATTTAAAAGGGATTGCGAC	TTAAAATACTCAGTTGTGGTTGTCCTGCTCTTTAT
GTAGGAAACAAGACCTCATTTAAAAGGGATTGCGAG

>NC_011296|2|2|632030-633918|CRT
GTAGGAAACAAGACCTCATTTAAAAGGGATTGCGAC	TTCATTGCTTATTTTATCAATTTCATCTTCAACTTGTTT
GTAGGAAACAAGACCTCATTTAAAAGGGATTGCGAC	TTCTCTTTTAAATAGATATCGTGAGGGCAAATTTT
GTAGGAAACAAGACCTCATTTAAAAGGGATTGCGAC	CTAAAGTATCCTTTATCTCTTGTATAAGAGATTG
GTAGGAAACAAGACCTCATTTAAAAGGGATTGCGAC	ATAATTTGATAGTTCTAAATCTTGTCCTATTATCTCA
GTAGGAAACAAGACCTCATTTAAAAGGGATTGCGAC	CGCTAGTTGGTATAACTACATGATAAAAATCAGTT
GTAGGAAACAAGACCTCATTTAAAAGGGATTGCGAC	TTTTTCTTTTTTACAATATTCTCTACTTCTTT
GTAGGAAACAAGACCTCATTTAAAAGGGATTGCGAC	ATCAAAAACCACTATTTCCTTTGCTTCTTTTTGTTG
GTAGGAAACAAGACCTCATTTAAAAGGGATTGCGAC	TTTGACTATGTCATTTGTTTGACATGGGAAAGTTGA
GTAGGAAACAAGACCTCATTTAAAAGGGATTGCGAC	CAATTTCAATTAATTCTTTCATTTTCCCCTCCGAT
GTAGGAAACAAGACCTCATTTAAAAGGGATTGCGAC	TTCAAGTCCCATCTCCTTGTAAATTTTCTTCTTCTC
GTAGGAAACAAGACCTCATTTAAAAGGGATTGCGAC	TTTAAGGCGGCGATAAGTGTCTCTTGCTTTTGTCCT
GTAGGAAACAAGACCTCATTTAAAAGGGATTGCGAC	CCATTTTTACCTCCCTTTTTGGTTTTGTAAAAA
GTAGGAAACAAGACCTCATTTAAAAGGGATTGCGAC	TAATTGGTTTAATGATACCCCGATATGGGTCCAAT
GTAGGAAACAAGACCTCATTTAAAAGGGATTGCGAC	ATTTTGTTCCTCTTCCTTTGCCCACTCCCAATCT
GTAGGAAACAAGACCTCATTTAAAAGGGATTGCGAC	ATAACGTATCATATCAAATATTACAAGGATTTTCCCT
GTAGGAAACAAGACCTCATTTAAAAGGGATTGCGAC	TTAATCCATAAGTTATATTGTCTTCTTTAAAATAA
GTAGGAAACAAGACCTCATTTAAAAGGGATTGCGAC	ATCCATTTTTGAGTGCATTTTCAAAGACCTGAAGTC
GTAGGAAACAAGACCTCATTTAAAAGGGATTGCGAC	CAAGCACTATAGCAGCACCACCGCACACAAACCCAA
GTAGGAAACAAGACCTCATTTAAAAGGGATTGCGAC	TGCAGTAAACGCAATAGGCGGCAGAGTTATGTCAG
GTAGGAAACAAGACCTCATTTAAAAGGGATTGCGAC	GGCTTTTCCTTTGCAGCATCAATTGCTGCAACTT
GTAGGAAACAAGACCTCATTTAAAAGGGATTGCGAC	GATATGAAACCAGAGGATACTTATTCATTATGTTGT
GTAGGAAACAAGACCTCATTTAAAAGGGATTGCGAC	ATAAAACCTCCTATATGTTTCATTTCTTCTTTAACT
GTAGGAAACAAGACCTCATTTAAAAGGGATTGCGAC	CACACATAGTAACATAAGTTGTAACGGCAACAT
GTAGGAAACAAGACCTCATTTAAAAGGGATTGCGAC	TCAAAGAATCCCAGAAGGGTGCACCAACTATCTGT
GTAGGAAACAAGACCTCATTTAAAAGGGATTGCGAC	ATGAATCATTGTATTGTAGTCCTGATAGCAGATTCT
GTAGGAAACAAGACCTCATTTAAAAGGGATTGCGAC	TTAAAATACTCAGTTGTGGTTGTCCTGCTCTTTAT
GTAGGAAACAAGACCTCATTTAAAAGGGATTGCGAG

Protein	Signature genes	Signature genes Name	Protein_function
NC_011296.1\|WP_012546007.1\|642581_642857_+\|CRISPR-associated-endonuclease-Cas2	cas2	cd09725_cas2_CAS-I:CAS-II:CAS-III:CAS-V	gnl\|CDD\|187856
NC_011296.1\|WP_012545669.1\|643177_643651_+\|methylated-DNA--[protein]-cysteine-S-methyltransferase	unknown	unknown	gnl\|CDD\|223427
NC_011296.1\|WP_012546098.1\|621508_621907_-\|PaaI-family-thioesterase	unknown	unknown	gnl\|CDD\|239527
NC_011296.1\|WP_012546365.1\|628722_629637_+\|CRISPR-associated-protein,-Csm4-family	csm4gr5	mkCas0089_csm4gr5_CAS-III-A:CAS-III-D	gnl\|CDD\|224483
NC_011296.1\|WP_012545199.1\|640570_640849_+\|CRISPR-associated-endonuclease-Cas2	cas2	pfam09827_cas2_CAS-I:CAS-II:CAS-III	gnl\|CDD\|187856
NC_011296.1\|WP_012546247.1\|640853_641810_+\|CRISPR-associated-endonuclease-Cas1	cas1	cd09634_cas1_CAS-I:CAS-II:CAS-III:CAS-V	gnl\|CDD\|376633
NC_011296.1\|WP_012545516.1\|643658_644396_+\|ATP-binding-protein	unknown	unknown	gnl\|CDD\|377544
NC_011296.1\|WP_012546877.1\|641766_642585_+\|hypothetical-protein	cas1	pfam01867_cas1_CAS-I:CAS-II:CAS-III	gnl\|CDD\|187766
NC_011296.1\|WP_012546826.1\|634161_634512_+\|hypothetical-protein	unknown	unknown	unknown
NC_011296.1\|WP_012546332.1\|637465_640561_+\|AAA-family-ATPase	unknown	unknown	gnl\|CDD\|223496
NC_011296.1\|WP_012545702.1\|630725_631622_+\|CRISPR-associated-endoribonuclease-Cas6	cas6	mkCas0066_cas6_CAS-I:CAS-III	gnl\|CDD\|187890
NC_011296.1\|WP_028842629.1\|621903_623154_-\|transcription-termination-factor-Rho	unknown	unknown	gnl\|CDD\|236490
NC_011296.1\|WP_012545271.1\|636315_637479_+\|DNA-repair-exonuclease	unknown	unknown	gnl\|CDD\|277319
NC_011296.1\|WP_012546108.1\|634543_636166_+\|DEAD/DEAH-box-helicase-family-protein	unknown	unknown	gnl\|CDD\|350770
NC_011296.1\|WP_012544968.1\|617600_621512_-\|phosphoribosylformylglycinamidine-synthase	unknown	unknown	gnl\|CDD\|178745
NC_011296.1\|WP_012546577.1\|623753_624863_+\|TIGR02584-family-CRISPR-associated-protein	csx1	cd09686_csx1_CAS-III	gnl\|CDD\|187817
NC_011296.1\|WP_012546668.1\|627549_627981_+\|type-III-A-CRISPR-associated-protein-Csm2	csm2gr11	pfam03750_csm2gr11_CAS-III-A	gnl\|CDD\|367635
NC_011296.1\|WP_012546605.1\|629638_630724_+\|type-III-A-CRISPR-associated-RAMP-protein-Csm5	csm5gr7	cd09662_csm5gr7_CAS-III-A	gnl\|CDD\|187793
NC_011296.1\|WP_012545508.1\|627984_628719_+\|type-III-A-CRISPR-associated-RAMP-protein-Csm3	csm3gr7	cd09684_csm3gr7_CAS-III-A:CAS-III-D	gnl\|CDD\|187815
NC_011296.1\|WP_012545463.1\|624967_627553_+\|type-III-A-CRISPR-associated-protein-Cas10/Csm1	cas10	cd09680_cas10_CAS-III	gnl\|CDD\|187811

Protein	Cas_name	Cas_description	E-value	Identity	Coverage
NC_011296.1\|WP_012546007.1\|642581_642857_+\|CRISPR-associated-endonuclease-Cas2	cas2	cd09725_cas2_CAS-I:CAS-II:CAS-III:CAS-V	4.5e-24	79.2	0.1
NC_011296.1\|WP_012546365.1\|628722_629637_+\|CRISPR-associated-protein,-Csm4-family	csm4gr5	mkCas0089_csm4gr5_CAS-III-A:CAS-III-D	4e-97	320.0	0.0
NC_011296.1\|WP_012545199.1\|640570_640849_+\|CRISPR-associated-endonuclease-Cas2	cas2	pfam09827_cas2_CAS-I:CAS-II:CAS-III	5.1e-21	69.6	0.2
NC_011296.1\|WP_012546577.1\|623753_624863_+\|TIGR02584-family-CRISPR-associated-protein	csx1	cd09686_csx1_CAS-III	1.7e-67	222.1	0.0
NC_011296.1\|WP_012546668.1\|627549_627981_+\|type-III-A-CRISPR-associated-protein-Csm2	csm2gr11	pfam03750_csm2gr11_CAS-III-A	1.1e-17	59.3	2.5
NC_011296.1\|WP_012546605.1\|629638_630724_+\|type-III-A-CRISPR-associated-RAMP-protein-Csm5	csm5gr7	cd09662_csm5gr7_CAS-III-A	2.9e-25	84.0	3.0
NC_011296.1\|WP_012545463.1\|624967_627553_+\|type-III-A-CRISPR-associated-protein-Cas10/Csm1	cas10	cd09680_cas10_CAS-III	2.7e-204	675.1	7.0
NC_011296.1\|WP_012546877.1\|641766_642585_+\|hypothetical-protein	cas1	pfam01867_cas1_CAS-I:CAS-II:CAS-III	9.4e-12	39.5	0.2
NC_011296.1\|WP_012545508.1\|627984_628719_+\|type-III-A-CRISPR-associated-RAMP-protein-Csm3	csm3gr7	cd09684_csm3gr7_CAS-III-A:CAS-III-D	8.9e-70	229.5	1.0
NC_011296.1\|WP_012546247.1\|640853_641810_+\|CRISPR-associated-endonuclease-Cas1	cas1	cd09634_cas1_CAS-I:CAS-II:CAS-III:CAS-V	2.4e-78	258.1	0.0
NC_011296.1\|WP_012545702.1\|630725_631622_+\|CRISPR-associated-endoribonuclease-Cas6	cas6	mkCas0066_cas6_CAS-I:CAS-III	1.4e-99	328.1	0.0

Protein	Function_ID	Function_description	E-value
NC_011296.1\|WP_012546007.1\|642581_642857_+\|CRISPR-associated-endonuclease-Cas2	gnl\|CDD\|187856	cd09725, Cas2_I_II_III, CRISPR/Cas system-associated protein Cas2. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas2 is present in majority of CRISPR/Cas systems along with Cas1; RNAse specific to U-rich regions; Possesses an RRM/ferredoxin fold.	1.52876e-23
NC_011296.1\|WP_012545669.1\|643177_643651_+\|methylated-DNA--[protein]-cysteine-S-methyltransferase	gnl\|CDD\|223427	COG0350, Ada, Methylated DNA-protein cysteine methyltransferase [DNA replication, recombination, and repair].	6.27016e-42
NC_011296.1\|WP_012546098.1\|621508_621907_-\|PaaI-family-thioesterase	gnl\|CDD\|239527	cd03443, PaaI_thioesterase, PaaI_thioesterase is a tetrameric acyl-CoA thioesterase with a hot dog fold and one of several proteins responsible for phenylacetic acid (PA) degradation in bacteria. Although orthologs of PaaI exist in archaea and eukaryotes, their function has not been determined. Sequence similarity between PaaI, E. coli medium chain acyl-CoA thioesterase II, and human thioesterase III suggests they all belong to the same thioesterase superfamily. The conserved fold present in these thioesterases is referred to as an asymmetric hot dog fold, similar to those of 4-hydroxybenzoyl-CoA thioesterase (4HBT) and the beta-hydroxydecanoyl-ACP dehydratases (FabA/FabZ).	1.86441e-19
NC_011296.1\|WP_012546365.1\|628722_629637_+\|CRISPR-associated-protein,-Csm4-family	gnl\|CDD\|224483	COG1567, COG1567, CRISPR system related protein, RAMP superfamily [Defense mechanisms].	2.16945e-09
NC_011296.1\|WP_012545199.1\|640570_640849_+\|CRISPR-associated-endonuclease-Cas2	gnl\|CDD\|187856	cd09725, Cas2_I_II_III, CRISPR/Cas system-associated protein Cas2. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas2 is present in majority of CRISPR/Cas systems along with Cas1; RNAse specific to U-rich regions; Possesses an RRM/ferredoxin fold.	5.033e-16
NC_011296.1\|WP_012546247.1\|640853_641810_+\|CRISPR-associated-endonuclease-Cas1	gnl\|CDD\|376633	pfam01867, Cas_Cas1, CRISPR associated protein Cas1. Clustered regularly interspaced short palindromic repeats (CRISPRs) are a family of DNA direct repeats found in many prokaryotic genomes. This family of proteins corresponds to Cas1, a CRISPR-associated protein. Cas1 may be involved in linking DNA segments to CRISPR.	2.74515e-93
NC_011296.1\|WP_012545516.1\|643658_644396_+\|ATP-binding-protein	gnl\|CDD\|377544	pfam05673, DUF815, Protein of unknown function (DUF815). This family consists of several bacterial proteins of unknown function.	3.68041e-98
NC_011296.1\|WP_012546877.1\|641766_642585_+\|hypothetical-protein	gnl\|CDD\|187766	cd09634, Cas1_I-II-III, CRISPR/Cas system-associated protein Cas1. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas1 is the most universal CRISPR system protein thought to be involved in spacer integration; Cas1 is metal-dependent deoxyribonuclease, also binds RNA; Shown to possess a unique fold consisting of a N-terminal beta-strand domain and a C-terminal alpha-helical domain.	0.00201365
NC_011296.1\|WP_012546332.1\|637465_640561_+\|AAA-family-ATPase	gnl\|CDD\|223496	COG0419, SbcC, ATPase involved in DNA repair [DNA replication, recombination, and repair].	4.92586e-49
NC_011296.1\|WP_012545702.1\|630725_631622_+\|CRISPR-associated-endoribonuclease-Cas6	gnl\|CDD\|187890	cd09760, Cas6_III, CRISPR/Cas system-associated RAMP superfamily protein Cas6. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas6 is an endoribonuclease that generates crRNAs, predicted subunit of Cascade complex.	2.2554e-09
NC_011296.1\|WP_028842629.1\|621903_623154_-\|transcription-termination-factor-Rho	gnl\|CDD\|236490	PRK09376, rho, transcription termination factor Rho; Provisional.	0
NC_011296.1\|WP_012545271.1\|636315_637479_+\|DNA-repair-exonuclease	gnl\|CDD\|277319	cd00840, MPP_Mre11_N, Mre11 nuclease, N-terminal metallophosphatase domain. Mre11 (also known as SbcD in Escherichia coli) is a subunit of the MRX protein complex. This complex includes: Mre11, Rad50, and Xrs2/Nbs1, and plays a vital role in several nuclear processes including DNA double-strand break repair, telomere length maintenance, cell cycle checkpoint control, and meiotic recombination, in eukaryotes. During double-strand break repair, the MRX complex is required to hold the two ends of a broken chromosome together. In vitro studies show that Mre11 has 3'-5' exonuclease activity on dsDNA templates and endonuclease activity on dsDNA and ssDNA templates. In addition to the N-terminal phosphatase domain, the eukaryotic MRE11 members of this family have a C-terminal DNA binding domain (not included in this alignment model). MRE11-like proteins are found in prokaryotes and archaea was well as in eukaryotes. Mre11 belongs to the metallophosphatase (MPP) superfamily. MPPs are functionally diverse, but all share a conserved domain with an active site consisting of two metal ions (usually manganese, iron, or zinc) coordinated with octahedral geometry by a cage of histidine, aspartate, and asparagine residues. The MPP superfamily includes: Mre11/SbcD-like exonucleases, Dbr1-like RNA lariat debranching enzymes, YfcE-like phosphodiesterases, purple acid phosphatases (PAPs), YbbF-like UDP-2,3-diacylglucosamine hydrolases, and acid sphingomyelinases (ASMases). The conserved domain is a double beta-sheet sandwich with a di-metal active site made up of residues located at the C-terminal side of the sheets. This domain is thought to allow for productive metal coordination.	4.19595e-47
NC_011296.1\|WP_012546108.1\|634543_636166_+\|DEAD/DEAH-box-helicase-family-protein	gnl\|CDD\|350770	cd18012, DEXQc_arch_SWI2_SNF2, DEAQ-box helicase domain of archaeal and bacterial SNF2-related proteins. Proteins belonging to SNF2 family of DNA dependent ATPases are important members of the chromatin remodeling complexes that are implicated in epigenetic control of gene expression. The Snf2 family comprises a large group of ATP-hydrolyzing proteins that are ubiquitous in eukaryotes, but also present in eubacteria and archaea. Archaeal SWI2 and SNF2 are members of the DEAD-like helicase superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.	1.39039e-51
NC_011296.1\|WP_012544968.1\|617600_621512_-\|phosphoribosylformylglycinamidine-synthase	gnl\|CDD\|178745	PLN03206, PLN03206, phosphoribosylformylglycinamidine synthase; Provisional.	0
NC_011296.1\|WP_012546577.1\|623753_624863_+\|TIGR02584-family-CRISPR-associated-protein	gnl\|CDD\|187817	cd09686, Csx1_III-U, CRISPR/Cas system-associated protein Csx1. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Protein of this family often fused to HTH domain; Some proteins could have an additional fusion with RecB-family nuclease domain; Core domain appears to have a Rossmann-like fold; loosely associated with CRISPR/Cas systems; also known as NE0113 family.	2.39436e-70
NC_011296.1\|WP_012546668.1\|627549_627981_+\|type-III-A-CRISPR-associated-protein-Csm2	gnl\|CDD\|367635	pfam03750, Csm2_III-A, Csm2 Type III-A. Clusters of short DNA repeats with non-homologous spacers, which are found at regular intervals in the genomes of phylogenetically distinct prokaryotic species, comprise a family with recognisable features. This family is known as CRISPR (short for Clustered Regularly Interspaced Short Palindromic Repeats). A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-associated) proteins. This entry represents Csm2 Type III-A, a family of Cas proteins also known as TM1810/Csm2.	4.44186e-17
NC_011296.1\|WP_012546605.1\|629638_630724_+\|type-III-A-CRISPR-associated-RAMP-protein-Csm5	gnl\|CDD\|187793	cd09662, Csm5_III-A, CRISPR/Cas system-associated RAMP superfamily protein Csm5. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; RAMP superfamily protein.	6.1981e-18
NC_011296.1\|WP_012545508.1\|627984_628719_+\|type-III-A-CRISPR-associated-RAMP-protein-Csm3	gnl\|CDD\|187815	cd09684, Csm3_III-A, CRISPR/Cas system-associated RAMP superfamily protein Csm3. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; RAMP superfamily protein.	1.88129e-72
NC_011296.1\|WP_012545463.1\|624967_627553_+\|type-III-A-CRISPR-associated-protein-Cas10/Csm1	gnl\|CDD\|187811	cd09680, Cas10_III, CRISPR/Cas system-associated protein Cas10. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Multidomain protein with permuted HD nuclease domain, palm domain and Zn-ribbon; signature gene for type III; also known as Csm1 family.	0

>NC_011296.1|WP_012545702.1|630725_631622_+|CRISPR-associated-endoribonuclease-Cas6
MRIEYKNIEFELKALTEIKLPDFKGSAFRGGFGHIFRKITCVLKRLNCLECPLKNQCIYSYVFETPPLENSNILNMSNYEKIPHPFIFEPPETKKKLFQPEETLNLKILLIGKAMEFAPYFIYTISELGKVGIGKGRGKFTVENINIGEKLLFHLNNINIRESYSVLKIRAITPLRIKYNRDLVRDIEFHILIRSLLRRLSLIYYFHIKPEILIHEPKELIRKAETVKKVQDITFWYDWERYSSRQDKRMKLGGVIGEIIYKGNISIFIPYVKAGEILHVGKGTSFGLGKYEIVEFST
>NC_011296.1|WP_012546605.1|629638_630724_+|type-III-A-CRISPR-associated-RAMP-protein-Csm5
MIYNVKLHTVSPIHIGCDQSYTPVNFVIDTDKSTLIEFDLWDFINSLDEKEYIKLRDISENKSPIALVYLYRFYAERKNRIKGRTIPIPKELADRYRDVKQFQNESDVIREFNEFEIPKTFYNPYTGKPLIPGSSLKGSIRTAYIEGLIKEEGNVAHYRDREKYPKYTDIEEKILQGKTKTDPFRLLKLSDFEPQGEVKTEIIFQVNVRKLNNTSKESLSIPIEIIPTGNVFKGTLAIEEPLAHSGISKKLDLTELLLKTHSHYAGIFNKEIDLRKIKGFSLPNLSEYREMFKQKYFLLRLGKHSGAEAVTWEGLRKIKVKTKEGTQIMDSSTTIWLASKQKKPSNLSSTTPFGWAILEVL
>NC_011296.1|WP_012546365.1|628722_629637_+|CRISPR-associated-protein,-Csm4-family
MKTYSVKIKPLTGFGDFIKGDTLFGHICWQLCYDPKIFGKSLDELLNDYDKNPFIVLSSAYPVVNNKIYLKRPALPLSMLFDISEEEIVKNRKELKRRNYFAFEQPLNLLRKINYESLSFFKEQEQTRCSINRLTNTTTEPPFAPYNVGKIFFNCDLVVFAGLRDDININSFLEILSRIGKHGYGKDATVGYGKFDIISWEEIDLLNTAKSPNALYTLSPLCPDSAQTEKIYFNPFVRFGRHGDILSKSKNPFKNPVIFADEAAIVFTKAEIIKPYIGKVVRDISKALPEAVTQGYSLVIKVEV
>NC_011296.1|WP_012545508.1|627984_628719_+|type-III-A-CRISPR-associated-RAMP-protein-Csm3
MQLREIKTIKGTIRLKTGLHIGSGNTEMQIGGTDNPVIKHPYTNEPYIPGSSLKGKIRSLVELYYGVVAEATKHDDMIKAGGLASSKMLEQSNGGIKKHIENILKVFGSGAGDTDEKLAKQLGPTRVSFSDCFLTDQFIKEAEEKRWSYIEVKSENRINRITGTAEHPRFIERVPAGAEFKLEISFKILNNGEEELFKNYLLKGLKLLEYDSLGGSGSRGYGKVEFIFDDETLKREYDEIKLWG
>NC_011296.1|WP_012546668.1|627549_627981_+|type-III-A-CRISPR-associated-protein-Csm2
MSNGGLPKIVFWADEKAEMINPDLFSTVAEAWAKKIKEVGKIAKDKNKISQIRKFYDEVLLFSDRVKNEDQFKKMLPYLKMLNAKAAYADGRNHITKEFKDFIQDCVSLVNTKKDFDIFVKFFEAFMGFYRYYDELFDRRMRR
>NC_011296.1|WP_012545463.1|624967_627553_+|type-III-A-CRISPR-associated-protein-Cas10/Csm1
MVDREILKIAIAALLHDIGKFSERASVEIPQDYVINNQALYQPKYNHRYTHRHSLHTAYFFDSFSKYLPKQILTDSTADTSLINLAAMHHKPTSAEQLIIREADILSSGIERKEFEEQDAQSRMPKEIPLSTIFEDISINENWKENKPESFKFVYPLATLSPKSIFPVEKSSLKQIDYKTLYEQFIELFKKLPHIEYSPLWFEHLDSLLFLFTSSIPSATVTRDDAGDFKEIITDISLYDHSRLTAAIATAFYAYHRETNSINIDAIKDRDIEKFLLIEGNFYGIQDFIFSDTGDTRKNAAKLLRGRSFYVSLLSELASDFIVEKIGLPSTSIVVNAAGKFRMILPNTERAIKLLAEAENEINDWLIKNFYGEVSIGISSVTASFNVLIDTETLSDIGKKLGKVSEERKFHKFDILKYAGAKTTYLNEFSSEFGICPLCNRRPAGDRNKIDDEHLCDVCFDHVNIGRNLTSKDYIAITYKDADLKDKLRIPIYNRYQLAFITGKLRDLVEAGKVRHFWDINSLWQEELHLSKELFSIKLINAYVPRFTEEHKDAEILEKLKYDESEESLKEIDNLINYGGILSFAHLGKLSLHKIDSEYQGVPALGVFKADVDNLGTIFMKGLRKEKRTFSRYTTLSRQLNLFFTLYVPYLCRTEFKNIYTVFTGGDDLFVIGPWKDTFEFALRVKEDFSKYCCENREISLSAGLFITKSETPVINMAKFSEEALDKAKQKGKNKLTVFDVSVSWDDLSKLAEIESHLHNWLEEEIITKAFSYKLNEIVKMVEEEIHLRQSNSFDLSSLNSLTWRAKLYYSTIRNVAKGYPKDKRIEIAEEVLTHLSLWLEKYRESMRIPLWKTLYMRRKA
>NC_011296.1|WP_012546577.1|623753_624863_+|TIGR02584-family-CRISPR-associated-protein
MYQKFKEVLVCVAGATPQIITETIYALAMKDPPIYIDELYIITTKKGEEIIKDVLIGGGILNSLFNEYGLSRTKITDIITIKNDNIEIDDIRNTEESEATAETIISFIRKITQNPNIRLHCSIAGGRKTMSFYLGTALQFFGRPQDKLYHVLVSPEFEANREFFYPPKKPRCIKCRIENSSFKMISTAEAKIELAELPFLRLRDKIELKEGTFKELMKISQNEIDIAIIQPQIKVKLKEREIKIVSDVLLLPPVMLTIYSFFLKRKIECDNAKACLSCNDCYLSLNKLTEEPFIDELASLYGFIYDKDPVKSSEFKENYTQKYATENLRSYISKINRKISQIVSDGSSYHYCLIKSIRKYGSTSVWSSN
>NC_011296.1|WP_028842629.1|621903_623154_-|transcription-termination-factor-Rho
MSISELKQKKIPELMDMANSLNIENATSMKKQDLIFAILQSQIEKIGTVYGAGVLEILPEGFGFLRSPDYSYLPSPDDIYVSPSQIRKFGLRTGDLITGQIRPPKENERYFALLKVESINGKPVEESIIRPLFDNLTPYYPTEKINLEYNPADYSTRVMDLLTPVGKGQRGLIVAAPRTGKTMLLQSIAKAIKKNHSEIYLIVLLIDERPEEVTDWRRQVTGAEIISSTFDEPAQRHCQVSEMVIERAKRLVEEGEDVVILLDSLTRLARAYNAITPASGKVLSGGLEATALQKPKRFFGTARNIEEGGSLTIIATALVETGSRMDDVIFEEFKGTGNMEVHLDRKLADKRIFPSIDIGASGTRKEELLVAPDVLNKVWILRKVLSTLSPIEAMEFLLSKLKGTKSNKEFLEMMNK
>NC_011296.1|WP_012546098.1|621508_621907_-|PaaI-family-thioesterase
MMKTEDYCFVCGKQNPVGLKVKFNHGEGKSFAELILTKEYQGWSGIIHGGIIASLLDEACVYAGNSLGYHTVTAELKIRFKNPVAPQEKIVVEAHAEHIKSKLIEAKAWIKNLNGTLIAEAESKLIIKEKTE
>NC_011296.1|WP_012544968.1|617600_621512_-|phosphoribosylformylglycinamidine-synthase
MILKFYRKGALSEYKTQQLLKRINSEISDEIKQVETEFCYYILTDKKLSEYELTILKWLLAETFEPENFSDKSFLSSDNGMIFEVGPRLNFSTAWSTCAVSVCHSIGINKIQRIERSRRYKLIPVIKNFPMKLFLDMIHDRMVECPYPEPLNDFSHGISPKPLRIVPVLEEGKKALEKINHELGLGWDEWDIEFYLKLFKDRLKRNPTDVECFDLAQSNSEHSRHWFFRGTLFIDGKPAEKTLFDIVKEPLKRNPKNSVIAFKDNSSAIYGAKIGYLKPEIPGKSCRFAIKRELHHLIFTAETHNFPTGVAPFPGAETGTGGRIRDVHATGKGAIPIAGTAAYCVGNLYIPNYELSWEDKSFKYPSNLATPLQIEIEASNGASDYGNKFGEPVIAGFTRSFGMRLPDGERVEWIKPIMFTGGIGQINAIHTEKDSPKKGMYVVKIGGPAYRIGMGGGAASSVVSGELSEELDFNAVQRGDAEMENKLNRVVRACVELGKKNPIVSIHDQGAGGNCNVVKELVYPEGAKIDIRKVILGDETLSVLEIWGAEYQENDAILIEKENVKLFGILCKRERLPWSIIGEVTGDGKLIVYDSKNNQIAVNFDLKDVLGEIPKKEFKLQTIEKKLKPLKIPETLTLKDALNRVLRLLSVGSKRFLTNKVDRSVTGLIVRQQCAGPVQLTVSDVCVVAQSYFNKTGIAHAIGEQPIKGLINPEAMARLSVTEALTNIVWAKITDIQDIKCSANWMWAAKLPGEGVRLYKAAQAMAEFMIKLGIAIDGGKDSLSMAAKVKTPDGVEVVKSPGSLVISAYAPCPDIQKIITPDIKSPDKSVILFIDLSNGKKRLGGTALAQCMGQLGDETPDMENPELLKRSFRAIQTLIDKKLILSGHDRSDGGLITTLLEMAFSGSCGLHIKIKEPKLSNIMAELFNEEPGLAIEVDIKKLDKVEKFLIQNEISFYRIADTLKENKIIIEHSNKIIFDEPMTSLRDIWEETSYRLDMLQANPECVEEEKKSIYGRIAPHYKLSFTPERTPEIILKKKTKPLIAIIREEGSNGDREMAAAFYMAGFEPWDVCMQDLIDKKISLKKFKGIAFVGGFSFADVLDSAKGWAGCIKFSHLKKEFENFYMRNDTFSLGVCNGCQLMALLGWVPWYGIEELKQPRFIWNKSGRFESRWVTVKILPSPSIMLKEMEDSQIGVWIAHGEGRAYFPDKNILSKVLEKNLAPVRYVDDSGNITETYPFNPNNSPYGITALCSEDGRHLAMMPHPERTFLLWQLPWLPQDWKKLKASPWLKLFQNARLWCDSHA
>NC_011296.1|WP_012546826.1|634161_634512_+|hypothetical-protein
MLKSLQTVPSILIVGKNYLLDTRKVTSYPVVYVRKAGETIDLSSSESSKIGKRERIECPTSKFQPIIVISHPDFSDDLAVAKQMLENIFILLDPLEPFNRMLKAIEVLGKQDKTFQ
>NC_011296.1|WP_012546108.1|634543_636166_+|DEAD/DEAH-box-helicase-family-protein
MKFLKDLRINLAKKLILKKKEDIFLLDKIEIDLKGGSPVKLKIPPFPTPQNIEHQYFQKPLVKDYNVNFPDCKHTCMYRISKDKLPEISVFEIRGKLFCPKIKAFAVNLGNPVVIGMSYKKYERKDRVSTLFPVSDDKLCIHGIERKLCSICNQRLQNKKTPIKSNFFQLILPILQPPLGENFDNPIAFQNKLKLYPFKIDGVKFLANHKQAILGDEMGLGKSIQAIVAIRLLFRIGEIVNVIIVCPKSVLTDWKKKLNDWAPELKVVKICGTPEQRKIIWYFPAHVYLITYDTLRQDENVSKKDFDLVILDEIQKIKNPSSGIPKAVRQVNGKIRWGLSGTPLENHLDELVSIFAYIKPGLLTYNDVQNLKKIKDLINPFFLRRRKQDVLKKLPKKVYEEVWLELTPERKAYNKVEQEGIVTLKKQGTSVTVQHIWALISKLKQICNLDPISNESCKLEYLPVAIQTEDRTHRIGQKKTVFVSSLFTVNTIEERIQNILNKKKQLFKEVIDHLSDTRLSKILSEEDLFSLFNIKKSKSK
>NC_011296.1|WP_012545271.1|636315_637479_+|DNA-repair-exonuclease
MSLKILHTSDWHLGKVFKETTFELLPIQKQIMDEIVDITRKENPDIVLIAGDIFDTYNPSFEAEKIFYETLSRLSEQNCFVFALAGNHDSPDKLQISKPLIAGKHSIFIKSTAFDESKDIEFENENFKLALENSFLKLHLKNEGTVIALKCLPYLSEVRLGLAGDEYLKKVNELLSIEPQFSCDYFLLTSHLSIAGAQQSGSERIFQIGGIEYIPIDFLPKSAHYIALGHLHRHQKLRNATYSGSIYPFDLAEIEHKKGVSVWENGKPDFIEFNKIPKIRKIEFDSLEDAVKNAPEDEAYYYVLIKNPHAYTTASIDALLKAYRNRLVNWQFYTPDVPEEISIPELHSLNEEEMFIEFYRAKLNKKPSQDILSLFLKTLEEVKNATN
>NC_011296.1|WP_012546332.1|637465_640561_+|AAA-family-ATPase
MLPISLIFEGLNSYAREVKIDFTKFYRTKLFGIFGITGGGKSTILDAIILSIYGKTPRLASTKIKEAINPQRGVINIEFTFEIGRRRFKIQRGIDQRETQIRLYRLEEDKEIPIAEKSNEFNEKIKEIIGLSYEEFCKVVILPQNQFAELLRLEPAKRAELIGNLFDLNYFGEPLYSKFSEKFLKLESTIQDKQRRLNELSEISQESIINKEREVDEITKALGELRQKQKELMEKLNILRNFKQLSDKKKELERELQKMETKKIEIESLKNKIQMDDELAPYKKSFEELKNLKKSIEANKQKHEELARELKIIESRFEKQREQKEEFEKFFSQRNEELIGKIKESEQLVELEQEIKSLLDKEQQRAKEMKKLNLEFKEVDEQLKRIDTETTQLMKNIEKNKALFENTQLNDEELRLYDLLPNALLKLNEIKNLKEEIEILIKKTERERKKWEESFAQIQKEFRDRFNLTIATYEEIDSVIVAKTEEIKELKDKLLRELDEFKVKNLAFTLSKTLLEGKPCPVCGSTEHPKPAESIDDKNIALREEKLKEVDENIFKIEDVKAKIKPLMEKVFISKTNIETYAKEISDKKSKLTKAEHELSQIISVKLWANAEQLFEQIKNKKKKNDEVMKELNYLNSEFHEKMKLKNDVTQKRVEIFTKIQQTHKELEEIKKDTKEKKDKLNEKTGGKTSYEIKTEAEKELEIIKKRSLQLENELKDLDIKKQNTLIAMERITEGIKKDEQKQKEIKASLDLKAKEMRIDVSELAAIILDEETKKSLKNTVEEFEKEFNKAKGALDNILKNLEEIPIKAIQPDELQETEKFIAETNDKIAQSNEKLGTLKEQIRKEKDMLKEKQLLSKEITLMENEFENVKLLKNLTYGKEMVKFFSWQLLKEIVKLTNGILRTLIGRRFSINVNPNLEFTVSDLLYNKERSVNTLSGGETFIVSFALALALSSYIQSKRMRAIQFFFIDEGFSSLDRELLDSVCAVLNELKSQDRLVGLISHIEELKQVIPNSINIKRDITGSSIVTFNV
>NC_011296.1|WP_012545199.1|640570_640849_+|CRISPR-associated-endonuclease-Cas2
MRVLYIIAYDITDARRLGQIRYFLKGYSTGGQKSVYECFLEREELKFIISKIKRLINPNEDRVHIFRIDGRSKVITLGIAVPPIDPEYFYIG
>NC_011296.1|WP_012546247.1|640853_641810_+|CRISPR-associated-endonuclease-Cas1
MSTVFIDRKDIEIRVDGNSISFYAKGKKDGSLPLSPLKRVVIVGNVKIETSVLYKLVNHGITVLFLTGKLKYSGILNGPLHNNGLLRVKQYQKSLSGFSLKFAKELIKRKIVSQRDFLSEIREIKKALAMQADRAIEILNKAISNIEVTPISIDSLRGIEGAASSIYFITYSKIFPNSLKFVRRIKRPPKDPVNAMLSLCYTLLHYEIVREIQLIGLDPTIGFYHQFEYGRESLACDLVELFRVNVDRFVYELFKAKHLGNRDFMKDEESGGVYLKKTGRKKFYPLYEQWVQQQRTIWRGEVQGFARRILEEKDIISG
>NC_011296.1|WP_012546877.1|641766_642585_+|hypothetical-protein
MQEEYLKKRTLYLVEKGNGTTVSRDGPSVLIERNFAAPVRIPADYIDKVIIYGNVEIDAFSITLFSSKFIPILIIGRHEESSIILPNTSELKSYTKYQIMMLDSKKIVESFINWIKERRAQNQKKVLNSLFENISISIEAEDRNYNVMINKIKPSDFLWSRVKEIMQNLIIITILSNLIKFKLDPHIGVINQGYNYGLVFDIYQIYEPYADFLTFQFFYADGANIDFIKNPDLNYDRLRFLIDKFEKKKDDIEQELNSSIAQILSFLRSIST
>NC_011296.1|WP_012546007.1|642581_642857_+|CRISPR-associated-endonuclease-Cas2
MRLPYLVCYDISDEGRLNRVYRFMKGKGFHIQYSVFYCILTDVELKEMKAEILKLIHSRYDDVRIYPLPNNSLVAVLGVGDRIPDGVEVFY
>NC_011296.1|WP_012545669.1|643177_643651_+|methylated-DNA--[protein]-cysteine-S-methyltransferase
MTPIGLLGIVFDSFLSVKKIFITDSDKNTTIPEFALNFVKQLNSYFKGELLEFNYPVNIQNISEFDKKVLEVTCEIPYGQTVTYNWLAKKLNTSPIAIGQALKRNPLPIIIPCHRVIKSDGTLGGYSLGIEIKKWLIEHERSTLYKFQLMKLHHRML
>NC_011296.1|WP_012545516.1|643658_644396_+|ATP-binding-protein
MFVQHQAFIWNGKEKSLKIVNRLPKYDIKELFGIDKQKELLLSNTKAFIEGKRVNNVLLWGERGTGKTTLIRSLLGYFKKSSLRMIQVLKNDIITMPYLYDIIYEHRDFRFIIFIDDLSFNENEQEFRDLKIVMDGGIEEIPENSVIYATSNRRNLMPAVSQSDNELFPEDSLQERASLIERFGLRIGFYRFSQEQYLDIVKHYATVAGIDLNPEELTKKAREWALIHGTTGRSAYQFVLSLQIF

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Crispr_ID: NC_011296_3

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_011296_3

1074817-1076909

TypeIII

Consensus_repeat	Method
GTTTTGAGCCTACCTATGAGGAATTGAAAC	CRISPRCasFinder
GTTTTGAGCCTACCTATGAGGAATTGAAAC	CRT
GTTTTGAGCCTACCTATGAGGAATTGAAAC	PILER-CR

31 spacers

cas2,cas1,cas4,cas5,cas7,csa5gr11,cmr3gr5,cmr5gr11,cmr4gr7,cas10

The CRISPR arrays of NC_011296_3

>merge|NC_011296|3|1074817-1076909|CRISPRCasFinder,CRT,PILER-CR
GTTTTGAGCCTACCTATGAGGAATTGAAACTTGTTTTGCCAAATTGATATTTCCAACCAGTTCCTCCGTTTTGAGCCTACCTATGAGGAATTGAAACTTGTATTCAGACAATAATTCTGTTCCTTCAAGCTTTGTTTTGAGCCTACCTATGAGGAATTGAAACAATAATCAAAATTATCAAGATTATCAGAGTTGTTATTGTTTTGAGCCTACCTATGAGGAATTGAAACGTTTTTTGGTGCATTTTCAAGACTTTTTATTGTTAGTTTTGAGCCTACCTATGAGGAATTGAAACGGTAAGTTATGTTCAGCCTTATGACCTTGTTAGAACGTTTTGAGCCTACCTATGAGGAATTGAAACTTGTATTCTTCTTTAAAAATCACATAGCCATTTATGTTTTGAGCCTACCTATGAGGAATTGAAACGTATCAGCTGTTGCATCTGCTGTTACAACAAACTGCGTTTTGAGCCTACCTATGAGGAATTGAAACGTTTGATACAGCTGCAGGATAGCCATTGACCTCTCGTTTTGAGCCTACCTATGAGGAATTGAAACTTAAAACTTCTCCATCTCTGGCTACGGTTCTAAGAAGTTTTGAGCCTACCTATGAGGAATTGAAACAACTATTTGTGGAGCAAGATATGCAGACAGCACTGCTACGTTTTGAGCCTACCTATGAGGAATTGAAACTTCAACTTCAACCCCGTATCTTGGAGTTGTTTCAGGTTTTGAGCCTACCTATGAGGAATTGAAACCGCATTTACTTATAACAATTATCATTTCATTTCCTTGTTTTGAGCCTACCTATGAGGAATTGAAACCATTTAAGCCCCACCAATAAGCATAGAATAAATAAAGTTTTGAGCCTACCTATGAGGAATTGAAACAAGCTCTCAGAGATAACATATGATGCAGTCGTCGGGTTTTGAGCCTACCTATGAGGAATTGAAACCGAGGCTCAAACAGGTGGAATACTTCAAACACAAGGGGTTTTGAGCCTACCTATGAGGAATTGAAACACTGTATTCTGTTTTTGTATCATTGAAGTGTGAAAGTTTTGAGCCTACCTATGAGGAATTGAAACATTTCTCTCTTAAAATACCTTTTAAAAATTTTTTTTGGTTTTGAGCCTACCTATGAGGAATTGAAACCTTTACACTCCATTGCAACTTCATAAACCATATTATTGTTTTGAGCCTACCTATGAGGAATTGAAACACATTTTGCCTGAACAGATATGTTTGCTCTAAGATGAGTTTTGAGCCTACCTATGAGGAATTGAAACTATCTATACCTTAACTCTCTCATACCTACCCTCTTTGTTTTGAGCCTACCTATGAGGAATTGAAACCCATGACGGCTTCAACACATCTTCAATTCTCGTTAAACCGTTTTGAGCCTACCTATGAGGAATTGAAACTTCAATTTCTAATTTTTTATTGTGTTCCATTTTTCTCCGTTTTGAGCCTACCTATGAGGAATTGAAACCTTGAAAAAACTTTTTTAAATCAATAACTTCATTATCCCGCGTTTTGAGCCTACCTATGAGGAATTGAAACTATTCTATAACTTTACCACCCTCATCCACACACACGTTTTGAGCCTACCTATGAGGAATTGAAACACTTTAATACTTCAAATTTCCTTTTACCTTTAGACAGTTTTGAGCCTACCTATGAGGAATTGAAACGTATTATTTGACATACCGCAAGCAAGCAAGAGATAGAGTTTTGAGCCTACCTATGAGGAATTGAAACTTTTATAACGCTCCCACACCATCTCCGCACTCGTCGTTTTGAGCCTACCTATGAGGAATTGAAACAACAAAATCGAACGAGGTTTAACGCTTTCATCAAACTCGTTTTGAGCCTACCTATGAGGAATTGAAACCCATACAAACCACCTTGCCCCAAAACATCGCATGGGTTTTGAGCCTACCTATGAGGAATTGAAACCTTTGTCAAGAACAAGCTCTTTCCATACTTTTGCACATTGTTTTGAGCCTACCTATGAGGAATTGAAACACAACAAACTCATACATTTGAAGTGCTCCCTGAGCCCGTTTTGAGCCTACCTATGAGGAATTGAAAC

>NC_011296|3|3|1074817-1076909|CRISPRCasFinder
GTTTTGAGCCTACCTATGAGGAATTGAAAC	TTGTTTTGCCAAATTGATATTTCCAACCAGTTCCTCC
GTTTTGAGCCTACCTATGAGGAATTGAAAC	TTGTATTCAGACAATAATTCTGTTCCTTCAAGCTTT
GTTTTGAGCCTACCTATGAGGAATTGAAAC	AATAATCAAAATTATCAAGATTATCAGAGTTGTTATT
GTTTTGAGCCTACCTATGAGGAATTGAAAC	GTTTTTTGGTGCATTTTCAAGACTTTTTATTGTTA
GTTTTGAGCCTACCTATGAGGAATTGAAAC	GGTAAGTTATGTTCAGCCTTATGACCTTGTTAGAAC
GTTTTGAGCCTACCTATGAGGAATTGAAAC	TTGTATTCTTCTTTAAAAATCACATAGCCATTTAT
GTTTTGAGCCTACCTATGAGGAATTGAAAC	GTATCAGCTGTTGCATCTGCTGTTACAACAAACTGC
GTTTTGAGCCTACCTATGAGGAATTGAAAC	GTTTGATACAGCTGCAGGATAGCCATTGACCTCTC
GTTTTGAGCCTACCTATGAGGAATTGAAAC	TTAAAACTTCTCCATCTCTGGCTACGGTTCTAAGAA
GTTTTGAGCCTACCTATGAGGAATTGAAAC	AACTATTTGTGGAGCAAGATATGCAGACAGCACTGCTAC
GTTTTGAGCCTACCTATGAGGAATTGAAAC	TTCAACTTCAACCCCGTATCTTGGAGTTGTTTCAG
GTTTTGAGCCTACCTATGAGGAATTGAAAC	CGCATTTACTTATAACAATTATCATTTCATTTCCTT
GTTTTGAGCCTACCTATGAGGAATTGAAAC	CATTTAAGCCCCACCAATAAGCATAGAATAAATAAA
GTTTTGAGCCTACCTATGAGGAATTGAAAC	AAGCTCTCAGAGATAACATATGATGCAGTCGTCGG
GTTTTGAGCCTACCTATGAGGAATTGAAAC	CGAGGCTCAAACAGGTGGAATACTTCAAACACAAGGG
GTTTTGAGCCTACCTATGAGGAATTGAAAC	ACTGTATTCTGTTTTTGTATCATTGAAGTGTGAAA
GTTTTGAGCCTACCTATGAGGAATTGAAAC	ATTTCTCTCTTAAAATACCTTTTAAAAATTTTTTTTG
GTTTTGAGCCTACCTATGAGGAATTGAAAC	CTTTACACTCCATTGCAACTTCATAAACCATATTATT
GTTTTGAGCCTACCTATGAGGAATTGAAAC	ACATTTTGCCTGAACAGATATGTTTGCTCTAAGATGA
GTTTTGAGCCTACCTATGAGGAATTGAAAC	TATCTATACCTTAACTCTCTCATACCTACCCTCTTT
GTTTTGAGCCTACCTATGAGGAATTGAAAC	CCATGACGGCTTCAACACATCTTCAATTCTCGTTAAACC
GTTTTGAGCCTACCTATGAGGAATTGAAAC	TTCAATTTCTAATTTTTTATTGTGTTCCATTTTTCTCC
GTTTTGAGCCTACCTATGAGGAATTGAAAC	CTTGAAAAAACTTTTTTAAATCAATAACTTCATTATCCCGC
GTTTTGAGCCTACCTATGAGGAATTGAAAC	TATTCTATAACTTTACCACCCTCATCCACACACAC
GTTTTGAGCCTACCTATGAGGAATTGAAAC	ACTTTAATACTTCAAATTTCCTTTTACCTTTAGACA
GTTTTGAGCCTACCTATGAGGAATTGAAAC	GTATTATTTGACATACCGCAAGCAAGCAAGAGATAGA
GTTTTGAGCCTACCTATGAGGAATTGAAAC	TTTTATAACGCTCCCACACCATCTCCGCACTCGTC
GTTTTGAGCCTACCTATGAGGAATTGAAAC	AACAAAATCGAACGAGGTTTAACGCTTTCATCAAACTC
GTTTTGAGCCTACCTATGAGGAATTGAAAC	CCATACAAACCACCTTGCCCCAAAACATCGCATGG
GTTTTGAGCCTACCTATGAGGAATTGAAAC	CTTTGTCAAGAACAAGCTCTTTCCATACTTTTGCACATT
GTTTTGAGCCTACCTATGAGGAATTGAAAC	ACAACAAACTCATACATTTGAAGTGCTCCCTGAGCCC
GTTTTGAGCCTACCTATGAGGAATTGAAAC

>NC_011296|3|3|1074817-1076909|CRT
GTTTTGAGCCTACCTATGAGGAATTGAAAC	TTGTTTTGCCAAATTGATATTTCCAACCAGTTCCTCC
GTTTTGAGCCTACCTATGAGGAATTGAAAC	TTGTATTCAGACAATAATTCTGTTCCTTCAAGCTTT
GTTTTGAGCCTACCTATGAGGAATTGAAAC	AATAATCAAAATTATCAAGATTATCAGAGTTGTTATT
GTTTTGAGCCTACCTATGAGGAATTGAAAC	GTTTTTTGGTGCATTTTCAAGACTTTTTATTGTTA
GTTTTGAGCCTACCTATGAGGAATTGAAAC	GGTAAGTTATGTTCAGCCTTATGACCTTGTTAGAAC
GTTTTGAGCCTACCTATGAGGAATTGAAAC	TTGTATTCTTCTTTAAAAATCACATAGCCATTTAT
GTTTTGAGCCTACCTATGAGGAATTGAAAC	GTATCAGCTGTTGCATCTGCTGTTACAACAAACTGC
GTTTTGAGCCTACCTATGAGGAATTGAAAC	GTTTGATACAGCTGCAGGATAGCCATTGACCTCTC
GTTTTGAGCCTACCTATGAGGAATTGAAAC	TTAAAACTTCTCCATCTCTGGCTACGGTTCTAAGAA
GTTTTGAGCCTACCTATGAGGAATTGAAAC	AACTATTTGTGGAGCAAGATATGCAGACAGCACTGCTAC
GTTTTGAGCCTACCTATGAGGAATTGAAAC	TTCAACTTCAACCCCGTATCTTGGAGTTGTTTCAG
GTTTTGAGCCTACCTATGAGGAATTGAAAC	CGCATTTACTTATAACAATTATCATTTCATTTCCTT
GTTTTGAGCCTACCTATGAGGAATTGAAAC	CATTTAAGCCCCACCAATAAGCATAGAATAAATAAA
GTTTTGAGCCTACCTATGAGGAATTGAAAC	AAGCTCTCAGAGATAACATATGATGCAGTCGTCGG
GTTTTGAGCCTACCTATGAGGAATTGAAAC	CGAGGCTCAAACAGGTGGAATACTTCAAACACAAGGG
GTTTTGAGCCTACCTATGAGGAATTGAAAC	ACTGTATTCTGTTTTTGTATCATTGAAGTGTGAAA
GTTTTGAGCCTACCTATGAGGAATTGAAAC	ATTTCTCTCTTAAAATACCTTTTAAAAATTTTTTTTG
GTTTTGAGCCTACCTATGAGGAATTGAAAC	CTTTACACTCCATTGCAACTTCATAAACCATATTATT
GTTTTGAGCCTACCTATGAGGAATTGAAAC	ACATTTTGCCTGAACAGATATGTTTGCTCTAAGATGA
GTTTTGAGCCTACCTATGAGGAATTGAAAC	TATCTATACCTTAACTCTCTCATACCTACCCTCTTT
GTTTTGAGCCTACCTATGAGGAATTGAAAC	CCATGACGGCTTCAACACATCTTCAATTCTCGTTAAACC
GTTTTGAGCCTACCTATGAGGAATTGAAAC	TTCAATTTCTAATTTTTTATTGTGTTCCATTTTTCTCC
GTTTTGAGCCTACCTATGAGGAATTGAAAC	CTTGAAAAAACTTTTTTAAATCAATAACTTCATTATCCCGC
GTTTTGAGCCTACCTATGAGGAATTGAAAC	TATTCTATAACTTTACCACCCTCATCCACACACAC
GTTTTGAGCCTACCTATGAGGAATTGAAAC	ACTTTAATACTTCAAATTTCCTTTTACCTTTAGACA
GTTTTGAGCCTACCTATGAGGAATTGAAAC	GTATTATTTGACATACCGCAAGCAAGCAAGAGATAGA
GTTTTGAGCCTACCTATGAGGAATTGAAAC	TTTTATAACGCTCCCACACCATCTCCGCACTCGTC
GTTTTGAGCCTACCTATGAGGAATTGAAAC	AACAAAATCGAACGAGGTTTAACGCTTTCATCAAACTC
GTTTTGAGCCTACCTATGAGGAATTGAAAC	CCATACAAACCACCTTGCCCCAAAACATCGCATGG
GTTTTGAGCCTACCTATGAGGAATTGAAAC	CTTTGTCAAGAACAAGCTCTTTCCATACTTTTGCACATT
GTTTTGAGCCTACCTATGAGGAATTGAAAC	ACAACAAACTCATACATTTGAAGTGCTCCCTGAGCCC
GTTTTGAGCCTACCTATGAGGAATTGAAAC

>NC_011296|3|3|1075082-1076909|PILER-CR
GTTTTGAGCCTACCTATGAGGAATTGAAAC	GGTAAGTTATGTTCAGCCTTATGACCTTGTTAGAAC
GTTTTGAGCCTACCTATGAGGAATTGAAAC	TTGTATTCTTCTTTAAAAATCACATAGCCATTTAT
GTTTTGAGCCTACCTATGAGGAATTGAAAC	GTATCAGCTGTTGCATCTGCTGTTACAACAAACTGC
GTTTTGAGCCTACCTATGAGGAATTGAAAC	GTTTGATACAGCTGCAGGATAGCCATTGACCTCTC
GTTTTGAGCCTACCTATGAGGAATTGAAAC	TTAAAACTTCTCCATCTCTGGCTACGGTTCTAAGAA
GTTTTGAGCCTACCTATGAGGAATTGAAAC	AACTATTTGTGGAGCAAGATATGCAGACAGCACTGCTAC
GTTTTGAGCCTACCTATGAGGAATTGAAAC	TTCAACTTCAACCCCGTATCTTGGAGTTGTTTCAG
GTTTTGAGCCTACCTATGAGGAATTGAAAC	CGCATTTACTTATAACAATTATCATTTCATTTCCTT
GTTTTGAGCCTACCTATGAGGAATTGAAAC	CATTTAAGCCCCACCAATAAGCATAGAATAAATAAA
GTTTTGAGCCTACCTATGAGGAATTGAAAC	AAGCTCTCAGAGATAACATATGATGCAGTCGTCGG
GTTTTGAGCCTACCTATGAGGAATTGAAAC	CGAGGCTCAAACAGGTGGAATACTTCAAACACAAGGG
GTTTTGAGCCTACCTATGAGGAATTGAAAC	ACTGTATTCTGTTTTTGTATCATTGAAGTGTGAAA
GTTTTGAGCCTACCTATGAGGAATTGAAAC	ATTTCTCTCTTAAAATACCTTTTAAAAATTTTTTTTG
GTTTTGAGCCTACCTATGAGGAATTGAAAC	CTTTACACTCCATTGCAACTTCATAAACCATATTATT
GTTTTGAGCCTACCTATGAGGAATTGAAAC	ACATTTTGCCTGAACAGATATGTTTGCTCTAAGATGA
GTTTTGAGCCTACCTATGAGGAATTGAAAC	TATCTATACCTTAACTCTCTCATACCTACCCTCTTT
GTTTTGAGCCTACCTATGAGGAATTGAAAC	CCATGACGGCTTCAACACATCTTCAATTCTCGTTAAACC
GTTTTGAGCCTACCTATGAGGAATTGAAAC	TTCAATTTCTAATTTTTTATTGTGTTCCATTTTTCTCC
GTTTTGAGCCTACCTATGAGGAATTGAAAC	CTTGAAAAAACTTTTTTAAATCAATAACTTCATTATCCCGC
GTTTTGAGCCTACCTATGAGGAATTGAAAC	TATTCTATAACTTTACCACCCTCATCCACACACAC
GTTTTGAGCCTACCTATGAGGAATTGAAAC	ACTTTAATACTTCAAATTTCCTTTTACCTTTAGACA
GTTTTGAGCCTACCTATGAGGAATTGAAAC	GTATTATTTGACATACCGCAAGCAAGCAAGAGATAGA
GTTTTGAGCCTACCTATGAGGAATTGAAAC	TTTTATAACGCTCCCACACCATCTCCGCACTCGTC
GTTTTGAGCCTACCTATGAGGAATTGAAAC	AACAAAATCGAACGAGGTTTAACGCTTTCATCAAACTC
GTTTTGAGCCTACCTATGAGGAATTGAAAC	CCATACAAACCACCTTGCCCCAAAACATCGCATGG
GTTTTGAGCCTACCTATGAGGAATTGAAAC	CTTTGTCAAGAACAAGCTCTTTCCATACTTTTGCACATT
GTTTTGAGCCTACCTATGAGGAATTGAAAC	ACAACAAACTCATACATTTGAAGTGCTCCCTGAGCCC
GTTTTGAGCCTACCTATGAGGAATTGAAAC

Protein	Signature genes	Signature genes Name	Protein_function
NC_011296.1\|WP_012546196.1\|1080101_1080830_+\|tetratricopeptide-repeat-protein	unknown	unknown	gnl\|CDD\|276809
NC_011296.1\|WP_012544918.1\|1080831_1082388_+\|murein-biosynthesis-integral-membrane-protein-MurJ	unknown	unknown	gnl\|CDD\|240528
NC_011296.1\|WP_012546006.1\|1068861_1070283_+\|type-I-A-CRISPR-associated-protein-Csa5	csa5gr11	cd09653_csa5gr11_CAS-I-A	gnl\|CDD\|273849
NC_011296.1\|WP_012545606.1\|1082384_1083014_+\|MBL-fold-metallo-hydrolase	unknown	unknown	gnl\|CDD\|293877
NC_011296.1\|WP_012545055.1\|1083000_1084647_+\|phosphate/phosphite/phosphonate-ABC-transporter-substrate-binding-protein	unknown	unknown	gnl\|CDD\|379006
NC_011296.1\|WP_012546538.1\|1066573_1067518_+\|type-III-B-CRISPR-module-RAMP-protein-Cmr4	cmr4gr7	COG1336_cmr4gr7_CAS-III-C	gnl\|CDD\|224255
NC_011296.1\|WP_012545077.1\|1076976_1080105_+\|transcription-repair-coupling-factor	unknown	unknown	gnl\|CDD\|224118
NC_011296.1\|WP_012545005.1\|1087638_1089222_-\|methyl-accepting-chemotaxis-protein	unknown	unknown	gnl\|CDD\|214599
NC_011296.1\|WP_012546410.1\|1086222_1087563_+\|sigma-54-dependent-Fis-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|225114
NC_011296.1\|WP_012545672.1\|1084609_1086220_+\|sensor-histidine-kinase	unknown	unknown	gnl\|CDD\|236901
NC_011296.1\|WP_012545513.1\|1090604_1092044_-\|NADH-quinone-oxidoreductase-subunit-M	unknown	unknown	gnl\|CDD\|223940
NC_011296.1\|WP_012545301.1\|1071605_1072379_+\|CRISPR-associated-protein-Cas5	cas5	COG1688_cas5_CAS-I	gnl\|CDD\|274218
NC_011296.1\|WP_021013193.1\|1074386_1074650_+\|CRISPR-associated-endonuclease-Cas2	cas2	cd09725_cas2_CAS-I:CAS-II:CAS-III:CAS-V	gnl\|CDD\|187856
NC_011296.1\|WP_012546600.1\|1089249_1090608_-\|NADH-quinone-oxidoreductase-subunit-N	unknown	unknown	gnl\|CDD\|235603
NC_011296.1\|WP_012545561.1\|1063608_1066560_+\|CRISPR-associated-protein-Csx11	cas10	cd09701_cas10_CAS-III-C	gnl\|CDD\|274257
NC_011296.1\|WP_012545127.1\|1067965_1068868_+\|hypothetical-protein	cmr3gr5	mkCas0067_cmr3gr5_CAS-III-C	unknown
NC_011296.1\|WP_012546660.1\|1070610_1071603_+\|DevR-family-CRISPR-associated-autoregulator	cas7	pfam01905_cas7_CAS-I	gnl\|CDD\|376656
NC_011296.1\|WP_012545370.1\|1072893_1073886_+\|type-I-B-CRISPR-associated-endonuclease-Cas1	cas1	cd09722_cas1_CAS-I-B	gnl\|CDD\|274695
NC_011296.1\|WP_012546197.1\|1072375_1072879_+\|CRISPR-associated-protein-Cas4	cas4	pfam01930_cas4_CAS-I	gnl\|CDD\|366863
NC_011296.1\|WP_012546344.1\|1067533_1067953_+\|hypothetical-protein	cmr5gr11	mkCas0060_cmr5gr11_CAS-III-C	unknown

Protein	Function_ID	Function_description	E-value
NC_011296.1\|WP_012546196.1\|1080101_1080830_+\|tetratricopeptide-repeat-protein	gnl\|CDD\|276809	sd00006, TPR, Tetratricopeptide repeat. The Tetratricopeptide repeat (TPR) typically contains 34 amino acids and is found in a variety of organisms including bacteria, cyanobacteria, yeast, fungi, plants, and humans. It is present in a variety of proteins including those involved in chaperone, cell-cycle, transcription, and protein transport complexes. The number of TPR motifs varies among proteins. Those containing 5-6 tandem repeats generate a right-handed helical structure with an amphipathic channel that is thought to accommodate an alpha-helix of a target protein. It has been proposed that TPR proteins preferentially interact with WD-40 repeat proteins, but in many instances several TPR-proteins seem to aggregate to multi-protein complexes.	7.00231e-20
NC_011296.1\|WP_012544918.1\|1080831_1082388_+\|murein-biosynthesis-integral-membrane-protein-MurJ	gnl\|CDD\|240528	cd13123, MATE_MurJ_like, MurJ/MviN, a subfamily of the multidrug and toxic compound extrusion (MATE)-like proteins. Escherichia coli MurJ (MviN) has been identified as essential for murein biosynthesis. It has been suggested that MurJ functions as the peptidoglycan lipid II flippase which is involved in translocation of lipid-anchored peptidoglycan precursors across the cytoplasmic membrane, though results obtained in Bacillus subtilis seem to indicate that its MurJ homologs are not essential for growth. Some MviN family members (e.g. in Mycobacterium tuberculosis) possess an extended C-terminal region that contains an intracellular pseudo-kinase domain and an extracellular domain resembling carbohydrate-binding proteins. Proteins from the MATE family are involved in exporting metabolites across the cell membrane and are often responsible for multidrug resistance (MDR).	5.73623e-157
NC_011296.1\|WP_012546006.1\|1068861_1070283_+\|type-I-A-CRISPR-associated-protein-Csa5	gnl\|CDD\|273849	TIGR01878, Uncharacterized_protein_AF_1870, CRISPR type I-A/APERN-associated protein Csa5. CRISPR is a term for Clustered, Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR-Associated) proteins. This model represents a minor family of Cas protein found in the (all archaeal) APERN subtype of CRISPR/Cas locus, so the family is designated Csa5, for CRISPR/Cas Subtype Protein 5.	4.39977e-24
NC_011296.1\|WP_012545055.1\|1083000_1084647_+\|phosphate/phosphite/phosphonate-ABC-transporter-substrate-binding-protein	gnl\|CDD\|379006	pfam12974, Phosphonate-bd, ABC transporter, phosphonate, periplasmic substrate-binding protein. This is a family of periplasmic proteins which are part of the transport system for alkylphosphonate uptake.	9.69946e-60
NC_011296.1\|WP_012546538.1\|1066573_1067518_+\|type-III-B-CRISPR-module-RAMP-protein-Cmr4	gnl\|CDD\|224255	COG1336, COG1336, CRISPR system related protein, RAMP superfamily [Defense mechanisms].	6.42811e-43
NC_011296.1\|WP_012545077.1\|1076976_1080105_+\|transcription-repair-coupling-factor	gnl\|CDD\|224118	COG1197, Mfd, Transcription-repair coupling factor (superfamily II helicase) [DNA replication, recombination, and repair / Transcription].	0
NC_011296.1\|WP_012545005.1\|1087638_1089222_-\|methyl-accepting-chemotaxis-protein	gnl\|CDD\|214599	smart00283, MA, Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). Thought to undergo reversible methylation in response to attractants or repellants during bacterial chemotaxis.	1.3579e-69
NC_011296.1\|WP_012546410.1\|1086222_1087563_+\|sigma-54-dependent-Fis-family-transcriptional-regulator	gnl\|CDD\|225114	COG2204, AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains [Signal transduction mechanisms].	0
NC_011296.1\|WP_012545672.1\|1084609_1086220_+\|sensor-histidine-kinase	gnl\|CDD\|236901	PRK11360, PRK11360, two-component system sensor histidine kinase AtoS.	5.09982e-61
NC_011296.1\|WP_012545513.1\|1090604_1092044_-\|NADH-quinone-oxidoreductase-subunit-M	gnl\|CDD\|223940	COG1008, NuoM, NADH:ubiquinone oxidoreductase subunit 4 (chain M) [Energy production and conversion].	1.67493e-104
NC_011296.1\|WP_012545301.1\|1071605_1072379_+\|CRISPR-associated-protein-Cas5	gnl\|CDD\|274218	TIGR02593, CRISPR-associated_protein_Cas5, CRISPR-associated protein Cas5, N-terminal domain. This model represents a shared N-terminal domain, about 43 amino acids in length, common to a number of related protein families each of which is associated with a distinct subtype of CRISPR/cas system, where CRISPR is an acronym for Clustered Regularly Interspaced Short Palindromic Repeat and Cas is an abbreviation for CRISPR-associated. Members of this family are widely distributed enough that we designated the family Cas5. Homology appears remote, or absent, between the more C-terminal regions different subfamilies of these proteins, which typically are 210 to 265 amino acids in total length. Cas5 proteins of six different CRISPR/cas subtypes so far defined are described by respective full-length models TIGR01868, TIGR01876, TIGR01895, TIGR01874, TIGR02586, and TIGR02592. The best characterized protein in this family is DevS or Myxococcus xanthus, a Cas protein that appears to participate in a species-specific developmental pathway.	2.85142e-11
NC_011296.1\|WP_021013193.1\|1074386_1074650_+\|CRISPR-associated-endonuclease-Cas2	gnl\|CDD\|187856	cd09725, Cas2_I_II_III, CRISPR/Cas system-associated protein Cas2. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas2 is present in majority of CRISPR/Cas systems along with Cas1; RNAse specific to U-rich regions; Possesses an RRM/ferredoxin fold.	5.751e-36
NC_011296.1\|WP_012546600.1\|1089249_1090608_-\|NADH-quinone-oxidoreductase-subunit-N	gnl\|CDD\|235603	PRK05777, PRK05777, NADH-quinone oxidoreductase subunit NuoN.	6.36702e-110
NC_011296.1\|WP_012545561.1\|1063608_1066560_+\|CRISPR-associated-protein-Csx11	gnl\|CDD\|274257	TIGR02682, hypothetical_protein_MM_3356, CRISPR-associated protein, Csx11 family. Members of this uncommon, sporadically distributed protein family are large (>900 amino acids) and strictly associated, so far, with CRISPR-associated (Cas) gene clusters. Nearby Cas genes always include members of the RAMP superfamily and the six-gene CRISPR-associated RAMP module. Species in which it is found, so far, include three archaea (Methanosarcina mazei, M. barkeri and Methanobacterium thermoautotrophicum) and two bacteria (Thermodesulfovibrio yellowstonii DSM 11347 and Sulfurihydrogenibium azorense).	0
NC_011296.1\|WP_012545606.1\|1082384_1083014_+\|MBL-fold-metallo-hydrolase	gnl\|CDD\|293877	cd16322, TTHA1623-like_MBL-fold, uncharacterized Thermus thermophilus TTHA1623 and related proteins; MBL-fold metallo hydrolase domain. Includes the MBL-fold metallo hydrolase domain of uncharacterized Thermus thermophilus TTHA1623 and related proteins. Members of this subgroup belong to the MBL-fold metallo-hydrolase superfamily which is comprised mainly of hydrolytic enzymes which carry out a variety of biological functions. This family includes homologs present in a wide range of bacteria and archaea and some eukaryota. Members of the MBL-fold metallo-hydrolase superfamily exhibit a variety of active site metallo-chemistry, TTHA1623 exhibiting a uniquely shaped putative substrate-binding pocket with a glyoxalase II-type metal-coordination mode.	4.90303e-81
NC_011296.1\|WP_012545370.1\|1072893_1073886_+\|type-I-B-CRISPR-associated-endonuclease-Cas1	gnl\|CDD\|274695	TIGR03641, cas1_HMARI, CRISPR-associated endonuclease Cas1, subtype I-B/HMARI/TNEAP. The CRISPR-associated protein Cas1 is virtually universal to CRISPR systems. CRISPR, an acronym for Clustered Regularly Interspaced Short Palindromic Repeats, is prokaryotic immunity system for foreign DNA, mostly from phage. CRISPR systems belong to different subtypes, distinguished by both nature of the repeats, the makeup of the cohort of associated Cas proteins, and by molecular phylogeny within the more universal Cas proteins such as this one. This model is of type EXCEPTION and provides more specific information than the EQUIVALOG model TIGR00287. It describes Cas1 subgroup that includes Cas1 proteins of the related HMARI and TNEAP subtypes of CRISPR/Cas system.	4.92147e-169
NC_011296.1\|WP_012546197.1\|1072375_1072879_+\|CRISPR-associated-protein-Cas4	gnl\|CDD\|366863	pfam01930, Cas_Cas4, Domain of unknown function DUF83. This domain has no known function. The domain contains three conserved cysteines at its C-terminus.	7.19834e-64
NC_011296.1\|WP_012546660.1\|1070610_1071603_+\|DevR-family-CRISPR-associated-autoregulator	gnl\|CDD\|376656	pfam01905, DevR, CRISPR-associated negative auto-regulator DevR/Csa2. This group of families is one of several protein families that are always found associated with prokaryotic CRISPRs, themselves a family of clustered regularly interspaced short palindromic repeats, DNA repeats found in nearly half of all bacterial and archaeal genomes. These DNA repeat regions have a remarkably regular structure: unique sequences of constant size, called spacers, sit between each pair of repeats. It has been shown that the CRISPRs are virus-derived sequences acquired by the host to enable them to resist viral infection. The Cas proteins from the host use the CRISPRs to mediate an antiviral response. After transcription of the CRISPR, a complex of Cas proteins termed Cascade cleaves a CRISPR RNA precursor in each repeat and retains the cleavage products containing the virus-derived sequence. Assisted by the helicase Cas3, these mature CRISPR RNAs then serve as small guide RNAs that enable Cascade to interfere with virus proliferation. Cas5 contains an endonuclease motif, whose inactivation leads to loss of resistance, even in the presence of phage-derived spacers. This family used to be known as DUF73. DevR appears to be negative auto-regulator within the system.	3.27124e-58

>NC_011296.1|WP_021013193.1|1074386_1074650_+|CRISPR-associated-endonuclease-Cas2
MRVILVYDINEKRVAKVLKTCRKYLHWVQNSVFEGEISEAKLEKLKIELKKIINPEEDSIIIYTFRSEWYTRREIIGIERGGEEIII
>NC_011296.1|WP_012545370.1|1072893_1073886_+|type-I-B-CRISPR-associated-endonuclease-Cas1
MKKSLYIISDGELKRKDNTLYFETSEERKYIPVENTREILIFGEVSMNKRLLEFLTESEIIIHFFNYYGYYIGSFYPREHLNSGYMILKQAEHYLDTGKRLNLAEKFVSGAIENIKKVLIYYHNRGKELSEIISKIQEIATNIPDCSTTDELMAIEGNIRDYYYQSFDIILDNEHFIFETRTKRPPKNRINALISFANSLVYTTCLSEIYQTHLDPRIGYLHATNFRRFTLNLDVAEIFKPIIADRAIFSIVNKRIVKPQHFEKKLDGIVLNDKGKQILLQEMDERLRSTIQHKKLGRHVSYRQLIRLELYKIQKHLMEEEEYKPFVTGW
>NC_011296.1|WP_012546197.1|1072375_1072879_+|CRISPR-associated-protein-Cas4
MNFNLKPSPTLIWYYFICEREVWLLSRQLEPYQANPFIEIGRLISEETYKRQLKEIHLENMVIDLLKTEGKDIVVAEVKKSSKYEKAARMQLAYYLLRLKAMGIEAKGELLFPVEKRKITVELTPEIQDELKEAQDKIKQIILHETAPLPKKIKFCNKCGYQELCWA
>NC_011296.1|WP_012545301.1|1071605_1072379_+|CRISPR-associated-protein-Cas5
MKALVFHIRLNSLYSIRIPFTWQSALTYPVPPPSAVIGMLANALQRYKNDRHPLQYLEKIENELIWAGSKLLSPCIIKSYTTSAIVKWDDTMPWKFTNAIGRQFAYAQQIQIATIFKDESIVNEIVKALKISPLTCGDSESPITIEDEVFIKNVYEIDKETITTGYPLPFSKDTKIKDGNGRVYLMHERCKKRHISLYLRTYLIPIVEIQGICHPSTIKIERTNEKFFKIDEIDFVVAYDSSSESRLEKKTNKKRKK
>NC_011296.1|WP_012546660.1|1070610_1071603_+|DevR-family-CRISPR-associated-autoregulator
MLKFITFSVKVQLNVHDLNNEAVAGNVTDIRIMEFLDEMGGKVEATAVSGRMLKHWHYEGMRKLGSAQGLPFCDACKIGEPVRPAKLENNILSHKNAVAEGQVAVIQKCAICDIHGYLAAIAGEGRGGRRTSEEGEEEQEGVSERRSSRVMFSWLMPVLGGEFSSRQVIHSRVKSGISFDDKNLTSQMPFHKSYGSGIYAFVSALDIDRIGLVELNLGSPNPYAVDDNSGRKQRIKVALEAYRLMLSGQLGASLSHAVPHVNPLEILVAYSETGPLPFPVSPIYPDYISKTVGLMPENTTLLYLGSETPTGVVKKNTINEVFDEILSKVA
>NC_011296.1|WP_012546006.1|1068861_1070283_+|type-I-A-CRISPR-associated-protein-Csa5
MLTLYTPATGFPDLDVKIAYGLTRVGIEAFGIESVAIHYEGGFYRVTFDIDKNDFEKLNKMFNLLCQRLLFSTYIPFSTPGIAGRSAESVTVNENESFSLDFYKSFTIIAKNKKGENVCRHEFDHIGNVIGFTVATSFHNKRDGVDIQLQYKNPKDKNSPKLPRRPTNPKNICKTCGLLALLGIWYTSFIFNVARKEVIVIPIPKGNVSGRKLQEIFALQHQIRKEWFNQDIPQVLIPLVFLSKIPSSADILKGFDLFIAILSRKQGYHVDRIFLIPIENYLKFIRGTPYNIATIDNILTQKAYAALQELNNTIYNLNKTSILKFARLYVQETSPKKGDWVNLLYPETVRYLLKEVAMISLEIIENPALGSLARTLRYFIREKKYGYADDIRNARKESRDFEETIAKMLREGRLRLEQKEQIHLPTDEEVKKVFRLANEDFESTKLALVMLAFSFPSRTEETMETLEEIQGVK
>NC_011296.1|WP_012545127.1|1067965_1068868_+|hypothetical-protein
MEWRLYKCIFRLKSSLYIGFHKIFHFYRTRYYVPGKIIWASLTYKLNGLLGINHYNKIGEFLKKAMRFGYLYLYVDNQLYLPSYTKEGLKLGQNLQYEFEKKFISSQAFATIDPHSFTAEEGMLHEVEFIKPYTINEGKPVFLKGLIWIRNIYEENLKIFIENNTLKIKAGEKEIDFRKQLINYLQLGGERKYGFGLIEINNFEEISDMVSEGFYGKWAVKNEDIIIYLPKDMPIFAHVKYSDSLELKGDIELLVEREWDLEKGAGRNIRSHGLCWVPGSLLKEDEKFKITEFGIWGKKC
>NC_011296.1|WP_012546344.1|1067533_1067953_+|hypothetical-protein
MENLDRLCAEYGFRFAEQITEAFNDAKKAESLITKALNVLQEQGLYAFALFCESRGEKEKVGANKLEEITKELLKEGLQVIQGDELLEEIRKEDGLASDLDRLIFSIEVIESSLIYARYHAKALSKESENQKTDDISIS
>NC_011296.1|WP_012546538.1|1066573_1067518_+|type-III-B-CRISPR-module-RAMP-protein-Cmr4
MSEFEFKKYCAIALDPIHIGSGGSRLGRVDLPIVREPGINLPKIPGTSISGPARAYTALQTNKYLWKHGEQEFSCAGRGGDGGEKHCGKINPACPVCIPYGFSKGTGNSIHGLAQFFDAHIVFFPVASMIGPVWITSPMALEGLGLQRNFAVNDNSFYPLGTQIQSDKLNFGWLMLKKDNSGQGNLNNLSPEISSDIIKQRAVLVSDRLFSHVVNRNLEVRTSVSIDPQTGTAEEKALFTYEAIPRGTVLAFDIIYNSGKALRIGGRELKTEGNADVGTAWVKAQVEKGLKLFEILGIGGMGTRGMGRIKILNI
>NC_011296.1|WP_012545561.1|1063608_1066560_+|CRISPR-associated-protein-Csx11
MNSLLEKLKNNRTAILLAEIGAYLHLLGRFSKEFIYSNAEDADPNCDNFDYQNICNDNRFFGNFSLKDLLQNDIWKTYLNKFISDKDLKDLKQNLTTFCDFIKKHTWTQTPQGLCKILADAHGIVSGIDKALAGRGKGGKQRKRYTFKTSAFGYGEKIELLENNKLKEEFFNALGEVLEKIKNGLPDISYEDYRNFISLIMNYYSKTIGETRRPINEISLFDYAHMIASLLKSNLVKIIGCGWYEPRGNSKWRVMRINIDVIGLISKGLKIGDISGYKNELDSVYDKLKKIIEYIYPLGNEIYRDSTGIYFSSPDMDISEVISKLREDLTCVDFELQISQSHSSRSLVSLASEREKSLSEIVFPHISKTKVSASMDHEGKDICPVCRIRLKEESKDRCIRCQERYEKRARSWLDKNERSKETIWIDEVADHNDRVALIFGQFDLRKWLSGEYLDTFISQTFESWRNENNSICSKLSINKIEDLEKQFESMFFKTINDNQKELCKSFIGIKPENFTKNFWEPIAERDATGQAMNLTNNPDKAKYLIKLLFRKHPSPARIRRIWNTTEDFIKNTLINNILSKHSYGEASSHVNLRNKRIQLIISPSPNIPIGSTIDIDIDGVRLSPVCVDKSKGIFITTTNLQILSIKGKTPEEISLWMKEKPIKVKKEGDVQWVGGYRITNVIPPNEAFQDYYPYIPIYNYPDQFMLLIPAYDALNIAQKIFEQYEVQFSKVMDRLPFHLGIIAFHRRTPLYIAMDAAKRLIKAFNTKTKTIKAKVESIEDTPENKHRKLTITPDQDFSSVPLEWQISYSTGDPNQEDEWHPYIRIENKPSHTGGYFFDYDGMGNYVVHVKGLKSNDCIKIETSYFKLVFLESASDRFRIDDNLRALDDIKRIDDLWNDIQNLVRNRNIGLAQVYAFWQETKKRYEDYNGDSIWKKFVSSSLINIFKLSPTRDRDLFKKFFQATKDGLLDICIHWNLKVRKQKP
>NC_011296.1|WP_012545077.1|1076976_1080105_+|transcription-repair-coupling-factor
MNFLSNQPSNINTALLEEVKKITSLIKTNNEIYNLSITSFSLFICFYKNNFIVFEENEDQAAKLYAAFKTFSSFFNTTDEIVFLPSKGTERMIAIFKILNERNKKIITTVDSAKIPPHIETINIKKGGTIEREFLAKNLINLGYSKVELVTQEGEFSEHGWVFDIWGIGEEYPARIEFFGDEIEEIKLFYPDTQRSFKDKNEIWIIQAEEKEINNIELLELFEFDNIFTVDKNFTNKKFNIVKISHLPVKFSTKSVDAGDKTFYGLGILPNERSSILDFPRNLKKLGIPIIFSISSRGKAETIKEVLFNHDIIAPLIHKNEIGTYSGKYAITISDLQEGFYRENLMIITDFELFGEKTLKKKKLAIQKLPIDGLEINEGDYIVHKEHGIGIFRGIKRQKYEGTEEDVLVLEYKDGDILYVPTWNIGKIYRYSAKEGFIPPIDKLGSNRWQKAKERERKRIHDIADKLIKLYAQRKTERGFIYSEDTEIHKNFDDFFPYEETEDQQKAIDAILKKMREPFPMEVLLCGDAGYGKTEVAMRASFRAVYDGKQVAVLVPTTLLCEQHYRTFKKRFEAFPVKIEYLSRFRSEKEIKKVIEDTKLGKVDILIGTHIIILKEVDFFDLGLLIIDEEQKFGVIHKEKIKEKYPKVDLITITATPIPRTLQIGLSGLWDIFVIQTPPKERLAVKTFVIQENELIIKEAIEKEIQRGGQIYFLHNRIHDIELVKSKIQKLVPMARIGVAHGRMKEKMLDKIMLDFIYGKIDILLCTSIIASGLDIPNVNTIIIDQAQTFGLSDLYQIRGRVGRSYRQANAYLVIPPEEILSEDAKKRIKAIQEMSYLGAGFHIALRDLEIRGAGELLGVEQSGVNRLGFDLYIEMLNEAVKEIKGEVLPALKLPEIKFSIPAFIPEEYIKETPMRIRIYRKLSQISEDSEIEKLYDEIIDRFGMPPKEVENIFKIARIRLLVSKIKASEVKQKKNTFKFKMEENLDTGFVNRLLHILTGFKNRGIIKNLKFYQDGFEVNIEELDGLILFLKRLIAKVEDKK
>NC_011296.1|WP_012546196.1|1080101_1080830_+|tetratricopeptide-repeat-protein
MIYYKTMRSKFLGVLIAFIVIACTSEERIRQMNESDFHKEIGFAYYIEKNYQLAYSEFHKALQIDPDNKDALHGLALVHMEFQEYEMAKDLFLRTLSLDNNYADAWFNLGVCYQKLNMHKEAIDAFQKALNNPLFVTQDKAYFGQGLSLYRVGQYEEAKNAFDKAIKRNVLLIPAHLYLALTYQKLNQYSEAVKTLKNSIKLDQSFKGDIDKFIKNLVDDLKKGQTNMPKEDILDLLEILKY
>NC_011296.1|WP_012544918.1|1080831_1082388_+|murein-biosynthesis-integral-membrane-protein-MurJ
MAKSKIVKAAGAISLATTFSRILGYIKDMILAKYFGATGISDVFFVAFRIPNLLRELFAEGSMSSAVIPVLKESQIKNGQEETQKIVKSLFTFIMIVVGIITILGIIFSPLIVKLIAPGFVENPQKFDLTVLLTRIMFPFLLFISLAALTMGTLNTNNIFFIPALAPCFLNIAIIIFIVGFSSLFFNPIISVAVGVTVGGALQWLVQTPTFYKNGFKFGIAPFHSALKKIAILVIPTTIAMAVNQINIFVSTIIASFLPEGSVTYLYYSMRLIQLPIGIFGVAVGMAVLPTLSQHVAEGKKDIFTKDFTFSLKFLFFLTIPSTLGLMMLKEPIINTLFQRGVFDITATINTAQALLFYSIGIIGTVGSRTITATFYSIQDTKTPVICAATAMLTNVIVSIALMNSMQHKGLALAYSVAATVQFFMLGYFIKRKIPQISFNSIISSFLKSFVAAFISVSIAKLICEINPSLWLHSEKMFLKFIWLACAISVAAFFYLVLCYLLKHEELGYILKKIRRQG
>NC_011296.1|WP_012545606.1|1082384_1083014_+|MBL-fold-metallo-hydrolase
MKIKKFEVGPLFVNCYIIYDERTKEAVVIDPGDEPDLILDFIKEENLNLKYILCTHGHFDHIGSVKELRDETGAKVVLHEKDIEIYRNSPQIAMQFFGIEIEPQPEPDILIKNGEILNTGNIQLTVIHTSGHSPGSVCFYTDGYIFTGDTLFAGSVGRTDIIGGSMNELLNSLKKIASLPDETIVFPGHGPKTKIGIEKKTNPFYHEVI
>NC_011296.1|WP_012545055.1|1083000_1084647_+|phosphate/phosphite/phosphonate-ABC-transporter-substrate-binding-protein
MKLFKFLLIVFLLISLSCSKSSKNENAKTSSQYSEGTSIIIGVLPEESPKVIYEKLYPLKKFLSENFKRPVLIDIARDFKDLEKKIKEDKINLIIVDPATYCELKWNMKNKIFPLIKPEGGIAETRSVFVTKQGNNIEKIFDSLGKKLALGEEKSSFSYLIPLSMLRDVDISIKDFKSVDMLQKEQRIALSILIGNHDIGAMSEITANKYLKDGLKIIRYSEPTPRFLIAYINNLKKDEVETIKNSILTRADRELLEAIGVEKFSLAEDRDFDYIRVLIKNLKGKDYIDYGSKTIKVAILPLYSPLTIYKRYDPLMRYLSEKTGYEFKLVIPKNFEEFINIVSQGKVHFSYQNPYVFSIVSKRYSIRPLAITVGEDCTTDEGICGNEKFRGLIITRKDSNIHKLTDLKGKKIMIVSPTSAGGYLSQKLYLEKKGFNLQRDFKLIDAKRQEKVIIGVYKGEADVGFIREAALSVWSNEVDISKIKILDYGDYLPNWPFAVVNNQNKELTEKVKKLITNIDNPLILKKAKIKAFKEATDEDFKILKILSN
>NC_011296.1|WP_012545672.1|1084609_1086220_+|sensor-histidine-kinase
MKILKYLKYLVTERIIKKLQRTSIGIKIFLSFLLLFLIIMISINLLILNYQKSSLKNQINTNITVLLENVSKDVIDHLVFFDPLAIDEKISIVMNNPGIDYIMLADKNGKIVGHSDKSQLGSYIKMEPSIYKRWQKSDTDGINHINLPVIVGDSYFGILRVGISEDKINAYIEQSTRNLKNYIYILSLIFFLLTVIMAFMLSKTLIKPLQRLKNKMSSIQADKLEICENPSTVFCKDIFNCEKSDCPAYGKERCWFITEAKENCKKCHNIDCKDCYVYKISCGDEIGYLIETFNEMILKLKHSLEELDRTTKEKLRLEKSSAMAEMAMTVAHEIKNPLNAIKASTSYLKANFQGEVLKEFLSIIDKETERLNELITSFLSYARPVPLKYEKGNINNALKDVIKLVETEIKEENKILQTDFDPSIPEFYFDHHQIKQAVLNLLVNATDATEKGDTIMIKTERIDGKIKITIKDSGTGIPEELMGKIFEPFFTTKTTGSGLGLACVERIIKDHEGNIKVTSKLNEGTEFTIELPIKEG
>NC_011296.1|WP_012546410.1|1086222_1087563_+|sigma-54-dependent-Fis-family-transcriptional-regulator
MANILYIDDEISALKAISAILRKEGYTVFTSTTAEEGMEVLKTTTIECILLDYRLPGMDGIDLLRWLKHCEMSIPTVMLTAYGTIEKAVEAMKLGAYHYLIKPVDTELLLNVIKEAIEKSKGIQKLEKIETPFPEIIGKSKTIQEIFYIMQMVAESNANVLITGESGTGKELVARAIHKNSLRKSKPFIIVDCTTIPENLLESELFGHEKGAFTGATERKTGLIELANEGTVFLDEIGELPMLLQKKLLRFLQEKEIQRIGSTQRIKVDVRVISATNKDLEKAIKEGSFREDLYWRLNVVRINLPPLRERKEDIPLLVNHFLNKFSKENNKPIPQLEPEVMNALINYYWPGNIRELANVIERAVVLSPSGLISIKHLPRRIQENTGWTIIKENTFNLLEVEKALILKALNSTGWNQTKAAEILGISRKQLRTKMKHHGFLTQSEEE
>NC_011296.1|WP_012545005.1|1087638_1089222_-|methyl-accepting-chemotaxis-protein
MNVKRLLQFINIMILLVLAGLFILSYFNEKGFQERVEKLTKKDIMLLVALNDMYAQGLQTGQATRNVFINPKDEQAKKNYQKAHQEFMKSNEAAIKLTKGEMQEQLKTIQQMWQKDHSMKMEIQQLAEQGKKDEAVKKIVEETKVWREIKDMIFKITDTHQKEFEKTNKEISEVRKRNAIIYSIVLFISLAGLSGMLYYSYKSYEKNMSSALGCFNRLEQGDLREEKTQACDLIGDIYQRITKSLRATIGKIREVVKNTNTMVASLSKETDDLEKNSREQLSRIDQMASASTEISQTIIDVAKNAAHASDSAKQANETAEKGKTAVDKAVKAMIDIANSIKAAAGTIEELGQSSQEIGEIVLTIKDIADQTNLLALNAAIEAARAGEQGRGFAVVADEVRKLAERTAKATEEIADKIRNIQSKSDASVNAMNASSSQAEGGVALANDAMRALDEIVSATEKAMDMIQRIAVATEELSATSEEIAQNMDTIRENINNTVKMIEFVRDITTKLSAETKALDESVEYFKV
>NC_011296.1|WP_012546600.1|1089249_1090608_-|NADH-quinone-oxidoreductase-subunit-N
MIQYKVLIPEISLLILAIISFFYGFISRNYRTTYILSFLSILTAIILSVFNFGQKEFTSELIKIDLYRQTLRILVLFIGVFIIGLSYSDLKLKSSKSVEYVFLLLLSLFGMNLMIVANDLLILYLALETFSLSLYILAGFYRKESLSIEAGMKYFILGTLSSIILLGSIVFFYAQTGSTSYETFKLLKTENLNILLGVVFLISAFAFKLSLAPFHAWAPDVYQGAPTAVTAFLSTAPKVAVFGALINIFLSINLKLNIQDLIVIISALSMLVGNVLALRQNNLKRMLAYSSIAHAGYMFMAFLLPEKELLISLIPYLIVYVFMNLSAFAFIMNIKNGESIQNYLGVGRKNPLLSFCIIVIMFSLTGVPPTAGFIVKFNLFKNLLSYGYGSLVFFALLMSIFSAFYYLRPVFYLYKDSLVIDIYNHPLNNSMALSGALLLIFLGLFPNLLLIF
>NC_011296.1|WP_012545513.1|1090604_1092044_-|NADH-quinone-oxidoreductase-subunit-M
MVGIELILIFPLLGAFLIWKIGIRKIVNLIALMSSSLSFIMALIYYLNFDRTKKGFQFLTSYEWISAWQLNFTLGFDHINSPFVLLTTFITLAIILLATKTIKDKISSFMSLLLLLSVSVNAFFMSTNFLQFFFFYEAMLIPAVLLIQRWGGENSFQASIKFLIYTFGFSIFLFLAIIATYYYGGSFSFTSLENLKISETAKLLLLFGFILAFFVKIPIVPLHGWLKDAYYEAAMPVTIFLSAVLGKMGIYGILRVIPYFNDILSVVNQWIILTCLISFVYSAFLALNSKNIKVLFAYMSLSHVGIITAGAFTGNLQGYQGVLLQSINHGILAAALFYVAELLNRETKSFDLEKFGALSKRVPALTFFTFSLIMAMGGFPGLNYFNGELLLLSGIFRENLFLGFIGVFGVALGVVYLSWFFYRVYLRKPGAELSTYVRDVISWELFFLAILLLISIYLGLNPDYVLSGVNEIVSFGGKG

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Crispr_ID: NC_011296_4

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_011296_4

1787448-1787627

Orphan

Consensus_repeat	Method
GTTGGAAAACAAGACCTCATTTAAAAGGGATT	CRISPRCasFinder

2 spacers

The CRISPR arrays of NC_011296_4

>merge|NC_011296|4|1787448-1787627|CRISPRCasFinder
GTTGGAAAACAAGACCTCATTTAAAAGGGATTGCGACAAACTTAAATTTTTCATGTCTTTCTCCTTTGAAGTTAGTTGGAAAACAAGACCTCATTTAAAAGGGATTGCGACTTATAAGCAGCTGCCTGAGCTTTGGTCAGACCGAATCGTTGGAAAACAAGACCTCATTTAAAAGGGATT

>NC_011296|4|4|1787448-1787627|CRISPRCasFinder
GTTGGAAAACAAGACCTCATTTAAAAGGGATT	GCGACAAACTTAAATTTTTCATGTCTTTCTCCTTTGAAGTTA
GTTGGAAAACAAGACCTCATTTAAAAGGGATT	GCGACTTATAAGCAGCTGCCTGAGCTTTGGTCAGACCGAATC
GTTGGAAAACAAGACCTCATTTAAAAGGGATT

Protein	Signature genes	Signature genes Name	Protein_function
NC_011296.1\|WP_012546392.1\|1794901_1797001_+\|UvrD-helicase-domain-containing-protein	unknown	unknown	gnl\|CDD\|273429
NC_011296.1\|WP_012546602.1\|1786027_1786396_-\|iron-molybdenum-cofactor-binding-protein	unknown	unknown	gnl\|CDD\|238431
NC_011296.1\|WP_012544984.1\|1797003_1797291_+\|Asp-tRNA(Asn)/Glu-tRNA(Gln)-amidotransferase-subunit-GatC	unknown	unknown	gnl\|CDD\|178810
NC_011296.1\|WP_012545247.1\|1782348_1783197_-\|AAA-family-ATPase	unknown	unknown	gnl\|CDD\|349764
NC_011296.1\|WP_012545451.1\|1781866_1782181_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|377579
NC_011296.1\|WP_164924931.1\|1783193_1783886_-\|class-I-SAM-dependent-methyltransferase	unknown	unknown	gnl\|CDD\|369777
NC_011296.1\|WP_012546690.1\|1786826_1787135_-\|DUF5320-domain-containing-protein	unknown	unknown	gnl\|CDD\|379955
NC_011296.1\|WP_012546378.1\|1781477_1781870_-\|helix-turn-helix-transcriptional-regulator	unknown	unknown	gnl\|CDD\|376540
NC_011296.1\|WP_012545497.1\|1791677_1793036_+\|UDP-N-acetylglucosamine-diphosphorylase/glucosamine-1-phosphate-N-acetyltransferase	unknown	unknown	gnl\|CDD\|224128
NC_011296.1\|WP_012545318.1\|1790309_1791065_+\|YebC/PmpR-family-DNA-binding-transcriptional-regulator	unknown	unknown	gnl\|CDD\|234640
NC_011296.1\|WP_012545099.1\|1793035_1794865_+\|glutamine--fructose-6-phosphate-transaminase-(isomerizing)	unknown	unknown	gnl\|CDD\|234729
NC_011296.1\|WP_012545946.1\|1789076_1789718_-\|formylmethanofuran-dehydrogenase-subunit-E	unknown	unknown	gnl\|CDD\|225102
NC_011296.1\|WP_012545235.1\|1785701_1786004_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|238431
NC_011296.1\|WP_012546573.1\|1797294_1797678_+\|aspartate-1-decarboxylase	unknown	unknown	gnl\|CDD\|376751
NC_011296.1\|WP_012546862.1\|1783833_1784565_-\|MBL-fold-metallo-hydrolase	unknown	unknown	gnl\|CDD\|293799
NC_011296.1\|WP_012545480.1\|1786406_1786784_-\|CGGC-domain-containing-protein	unknown	unknown	gnl\|CDD\|378059
NC_011296.1\|WP_012546603.1\|1791066_1791678_+\|DUF502-domain-containing-protein	unknown	unknown	gnl\|CDD\|225480
NC_011296.1\|WP_012545679.1\|1787844_1788318_+\|transcriptional-repressor	unknown	unknown	gnl\|CDD\|133478
NC_011296.1\|WP_012545035.1\|1788336_1789080_-\|sulfite-exporter-TauE/SafE-family-protein	unknown	unknown	gnl\|CDD\|376667
NC_011296.1\|WP_012545002.1\|1784566_1785409_-\|Mrp/NBP35-family-ATP-binding-protein	unknown	unknown	gnl\|CDD\|378455

Protein	Function_ID	Function_description	E-value
NC_011296.1\|WP_012546392.1\|1794901_1797001_+\|UvrD-helicase-domain-containing-protein	gnl\|CDD\|273429	TIGR01073, ATP-dependent_DNA_helicase_PcrA, ATP-dependent DNA helicase PcrA. Designed to identify pcrA members of the uvrD/rep subfamily. [DNA metabolism, DNA replication, recombination, and repair].	0
NC_011296.1\|WP_012546602.1\|1786027_1786396_-\|iron-molybdenum-cofactor-binding-protein	gnl\|CDD\|238431	cd00851, MTH1175, This uncharacterized conserved protein belongs to a family of iron-molybdenum cluster-binding proteins that includes NifX, NifB, and NifY, all of which are involved in the synthesis of an iron-molybdenum cofactor (FeMo-co) that binds the active site of the dinitrogenase enzyme. This domain is a predicted small-molecule-binding domain (SMBD) with an alpha/beta fold that is present either as a stand-alone domain (e.g. NifX and NifY) or fused to another conserved domain (e.g. NifB) however, its function is still undetermined.The SCOP database suggests that this domain is most similar to structures within the ribonuclease H superfamily. This conserved domain is represented in two of the three major divisions of life (bacteria and archaea).	4.91883e-32
NC_011296.1\|WP_012544984.1\|1797003_1797291_+\|Asp-tRNA(Asn)/Glu-tRNA(Gln)-amidotransferase-subunit-GatC	gnl\|CDD\|178810	PRK00034, gatC, Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatC.	5.60057e-38
NC_011296.1\|WP_012545247.1\|1782348_1783197_-\|AAA-family-ATPase	gnl\|CDD\|349764	cd03110, SIMIBI_bact_arch, bacterial and archaeal subfamily of SIMIBI. Uncharacterized bacterial and archaeal subfamily of SIMIBI superfamily. Proteins in this superfamily contain an ATP-binding domain and use energy from hydrolysis of ATP to transfer electron or ion. The specific function of this family is unknown.	4.4085e-129
NC_011296.1\|WP_012545451.1\|1781866_1782181_-\|hypothetical-protein	gnl\|CDD\|377579	pfam05973, Gp49, Phage derived protein Gp49-like (DUF891). This family consists of hypothetical bacterial proteins of unknown function as well as phage Gp49 proteins.	1.78907e-11
NC_011296.1\|WP_164924931.1\|1783193_1783886_-\|class-I-SAM-dependent-methyltransferase	gnl\|CDD\|369777	pfam08241, Methyltransf_11, Methyltransferase domain. Members of this family are SAM dependent methyltransferases.	7.41812e-20
NC_011296.1\|WP_012546690.1\|1786826_1787135_-\|DUF5320-domain-containing-protein	gnl\|CDD\|379955	pfam17253, DUF5320, Family of unknown function (DUF5320). A number of this family members have a coiled coil domain at the C terminal.	4.96254e-24
NC_011296.1\|WP_012546378.1\|1781477_1781870_-\|helix-turn-helix-transcriptional-regulator	gnl\|CDD\|376540	pfam01381, HTH_3, Helix-turn-helix. This large family of DNA binding helix-turn helix proteins includes Cro and CI. Within Neisseria gonorrhoeae NGO_0477, the full protein fold incorporates a helix-turn-helix motif, but the function of this member is unlikely to be that of a DNA-binding regulator, the function of most other members, so is not necessarily characteristic of the whole family.	8.83862e-08
NC_011296.1\|WP_012545497.1\|1791677_1793036_+\|UDP-N-acetylglucosamine-diphosphorylase/glucosamine-1-phosphate-N-acetyltransferase	gnl\|CDD\|224128	COG1207, GlmU, N-acetylglucosamine-1-phosphate uridyltransferase (contains nucleotidyltransferase and I-patch acetyltransferase domains) [Cell envelope biogenesis, outer membrane].	0
NC_011296.1\|WP_012545318.1\|1790309_1791065_+\|YebC/PmpR-family-DNA-binding-transcriptional-regulator	gnl\|CDD\|234640	PRK00110, PRK00110, YebC/PmpR family DNA-binding transcriptional regulator.	3.76854e-157
NC_011296.1\|WP_012545099.1\|1793035_1794865_+\|glutamine--fructose-6-phosphate-transaminase-(isomerizing)	gnl\|CDD\|234729	PRK00331, PRK00331, isomerizing glutamine--fructose-6-phosphate transaminase.	0
NC_011296.1\|WP_012545946.1\|1789076_1789718_-\|formylmethanofuran-dehydrogenase-subunit-E	gnl\|CDD\|225102	COG2191, COG2191, Formylmethanofuran dehydrogenase subunit E [Energy production and conversion].	5.827e-32
NC_011296.1\|WP_012545235.1\|1785701_1786004_-\|hypothetical-protein	gnl\|CDD\|238431	cd00851, MTH1175, This uncharacterized conserved protein belongs to a family of iron-molybdenum cluster-binding proteins that includes NifX, NifB, and NifY, all of which are involved in the synthesis of an iron-molybdenum cofactor (FeMo-co) that binds the active site of the dinitrogenase enzyme. This domain is a predicted small-molecule-binding domain (SMBD) with an alpha/beta fold that is present either as a stand-alone domain (e.g. NifX and NifY) or fused to another conserved domain (e.g. NifB) however, its function is still undetermined.The SCOP database suggests that this domain is most similar to structures within the ribonuclease H superfamily. This conserved domain is represented in two of the three major divisions of life (bacteria and archaea).	9.98982e-25
NC_011296.1\|WP_012546573.1\|1797294_1797678_+\|aspartate-1-decarboxylase	gnl\|CDD\|376751	pfam02261, Asp_decarbox, Aspartate decarboxylase. Decarboxylation of aspartate is the major route of beta-alanine production in bacteria, and is catalyzed by the enzyme aspartate decarboxylase EC:4.1.1.11 which requires a pyruvoyl group for its activity. It is synthesized initially as a proenzyme which is then proteolytically cleaved to an alpha (C-terminal) and beta (N-terminal) subunit and a pyruvoyl group. This family contains both chains of aspartate decarboxylase.	9.84631e-63
NC_011296.1\|WP_012546862.1\|1783833_1784565_-\|MBL-fold-metallo-hydrolase	gnl\|CDD\|293799	cd07713, DHPS-like_MBL-fold, Methanocaldococcus jannaschii dihydropteroate synthase, Thermoanaerobacter tengcongensis Tflp, and related proteins; MBL-fold metallo hydrolase domain. This subgroup includes Methanocaldococcus jannaschii 7,8-dihydropterin-6-methyl-4-(beta-D-ribofuranosyl)-aminobenzene-5'-phosphate synthase (EC 2.5.1.15), a folate biosynthetic enzyme also known as dihydropteroate synthase and 7,8 dihydropteroate synthase. Thermoanaerobacter tengcongensis Tflp is a ferredoxin-like member. Members of this subgroup belong to the MBL-fold metallo-hydrolase superfamily which is comprised mainly of hydrolytic enzymes which carry out a variety of biological functions.	1.41049e-66
NC_011296.1\|WP_012545480.1\|1786406_1786784_-\|CGGC-domain-containing-protein	gnl\|CDD\|378059	pfam08821, CGGC, CGGC domain. This putative domain contains a quite highly conserved sequence of CGGC in its central region. The domain has many conserved cysteines and histidines suggestive of a zinc binding function.	8.57703e-28
NC_011296.1\|WP_012546603.1\|1791066_1791678_+\|DUF502-domain-containing-protein	gnl\|CDD\|225480	COG2928, COG2928, Uncharacterized conserved protein [Function unknown].	1.42095e-39
NC_011296.1\|WP_012545679.1\|1787844_1788318_+\|transcriptional-repressor	gnl\|CDD\|133478	cd07153, Fur_like, Ferric uptake regulator(Fur) and related metalloregulatory proteins; typically iron-dependent, DNA-binding repressors and activators. Ferric uptake regulator (Fur) and related metalloregulatory proteins are iron-dependent, DNA-binding repressors and activators mainly involved in iron metabolism. A general model for Fur repression under iron-rich conditions is that activated Fur (a dimer having one Fe2+ coordinated per monomer) binds to specific DNA sequences (Fur boxes) in the promoter region of iron-responsive genes, hindering access of RNA polymerase, and repressing transcription. Positive regulation by Fur can be direct or indirect, as in the Fur repression of an anti-sense regulatory small RNA. Some members sense metal ions other than Fe2+. For example, the zinc uptake regulator (Zur) responds to Zn2+, the manganese uptake regulator (Mur) responds to Mn2+, and the nickel uptake regulator (Nur) responds to Ni2+. Other members sense signals other than metal ions. For example, PerR, a metal-dependent sensor of hydrogen peroxide. PerR regulates DNA-binding activity through metal-based protein oxidation, and co-ordinates Mn2+ or Fe2+ at its regulatory site. Fur family proteins contain an N-terminal winged-helix DNA-binding domain followed by a dimerization domain; this CD spans both those domains.	1.89564e-44
NC_011296.1\|WP_012545035.1\|1788336_1789080_-\|sulfite-exporter-TauE/SafE-family-protein	gnl\|CDD\|376667	pfam01925, TauE, Sulfite exporter TauE/SafE. This is a family of integral membrane proteins where the alignment appears to contain two duplicated modules of three transmembrane helices. The proteins are involved in the transport of anions across the cytoplasmic membrane during taurine metabolism as an exporter of sulfoacetate. This family used to be known as DUF81.	1.96717e-22
NC_011296.1\|WP_012545002.1\|1784566_1785409_-\|Mrp/NBP35-family-ATP-binding-protein	gnl\|CDD\|378455	pfam10609, ParA, NUBPL iron-transfer P-loop NTPase. This family contains ATPases involved in plasmid partitioning. It also contains the cytosolic Fe-S cluster assembling factor NBP35 which is required for biogenesis and export of both ribosomal subunits.	1.93352e-146

>NC_011296.1|WP_012546690.1|1786826_1787135_-|DUF5320-domain-containing-protein
MPGFDRTGPFGQGPMTGRGMGYCGGASRYMNSASGRRFGFGRGFRCLGGFRRRFRWLWRMPFFGGASSREEVEWLKEEAEILKRELEAVQRRLSEIEKEKAE
>NC_011296.1|WP_012545480.1|1786406_1786784_-|CGGC-domain-containing-protein
MKKIAILACKMIREQNLCPADAKCLVALSRKEGEFERYKNDDVSILGIMDCGGCEGNKTRAICSLLLFKTQLVALKENIDVLHIGTCMMKFCPRKDDIIAAVKEKAGIEIIEGTHKYAPPTIFGN
>NC_011296.1|WP_012546602.1|1786027_1786396_-|iron-molybdenum-cofactor-binding-protein
MRLAIATENGHVAQHFGRCPGFTVVDIENGKINSKNFIENPGYKAHQPGAVPMFLRNQNVDCVIAGGMGPNAVMNLQASGIKVIVGITGSIDETIEQFLNGSLKGGESLCEHGQHEHEGCKH
>NC_011296.1|WP_012545235.1|1785701_1786004_-|hypothetical-protein
MKICITSSGENLNSDIDPRFGRCNFFIFYDTDTKQYEAVENSWKEASGGAGIQAAQFVIQKGVKKVFTGRVGANAEMVLRKAGIEIVEASGKVDDIIKKY
>NC_011296.1|WP_012545002.1|1784566_1785409_-|Mrp/NBP35-family-ATP-binding-protein
MAEEKSCSCETEKEQRRRELTLKANVSAIKKKILVLSGKGGVGKSTVSTNLATGLAKKGYHVGLLDIDIHGPNIPNMLGLQGHSPLVTDMGLFPLKVFDNLQVISIGFFLEEKDTPVVWRGPLKHRMIEQFLSDVRWGELDYLVVDSPPGTGDEIISIVQLLDNVDGAVIVATPQEVALADVRRSIKFCKEASIPIIGIVENMSGFVCPHCGNTVEIFKTGGAEKLAEEYKVPFLGKIPVDPQIVKAGDEGKPMMIYFPEAKPAQAFAQVVEKITEKLKV
>NC_011296.1|WP_012546862.1|1783833_1784565_-|MBL-fold-metallo-hydrolase
MLIDIRILFDNYEGESGFRSGFGYSCFIKKGYGGILFDTGADNEILIHNLNKAEIKPQMITRVVLSHCHKDHTQGLTGIVNLKKDFNIYAGKSCAETLLNREELKNVNLTFVNSECVEIMNGVYLTGELGENIKEISLLMDTGGGLVVITGCAHAGLKEIFKKAKEIINDKIFALVGGLHLKDKKEEEIHELIEFLKSEGVRYIAPSHCTGDLARRLFKKSFHSGFIEAGAGSRIYIGGSCEY
>NC_011296.1|WP_164924931.1|1783193_1783886_-|class-I-SAM-dependent-methyltransferase
MKQEQAVASTSEEVVSIDEPFESYATQYDAWYDSERGKILYENEKKCLKKLINDCNGKVLEVGVGTGRFAVLAEEAFGVDVAEAPLRIAKLRGIRVIKAKAEELPFRDKVFSCVMLIVTLCFVKDPLLALKEAKRVLKEEGKVIIGDVFLDSEWGKLYAQKKKEGHLFYKLANFYSFENFKKIVSLVGLKIKRVFGTLKKSPFDEPSPEESEAIADDISSYGFVCVELTK
>NC_011296.1|WP_012545247.1|1782348_1783197_-|AAA-family-ATPase
MIISVASGKGGTGKTFFTGCLAVAVKNKVLVDCDVDAANLHLLLHPEIKESYEFIGGKLAQIDKTKCIECGLCRENCKFNAIGEDFQVDELSCEGCTICSYICPQEAIILRDRVSGQYFISETKYGTLIHARLGIAQENSGKLVTKLRKIAKETAEITGCQYIIIDGPPGVGCPVMASMTGVDLVVAVTEPTLSGMHDLGRVIELAKHFKIPLKVIINKFDLNPQMSENIEEELNKFEIELAGRIPFSEEILYSVKKGFPFLEFSQGKLSKEIESLIQNIFS
>NC_011296.1|WP_012545451.1|1781866_1782181_-|hypothetical-protein
MKKKIEIVLHEKVEEFILNLQERDRNKILQILCVLGERNLEVSSEWLKKVTENLWELRIRNCRLFYSIEGNTMKIWHGFIKKTMKIPKREIELALERMKKEEIR
>NC_011296.1|WP_012546378.1|1781477_1781870_-|helix-turn-helix-transcriptional-regulator
MRNLKDILKEQFKDKKFKEDFYRGLEKTRIATEIAYYREKRGITQVQLAKMLGTSQSTIARLEDPFYDNYSLNTLRKIAKVLDLELVVSLREKNERVQEEFSQRADRNTQQKINRKSNKKRGGKSLISIP
>NC_011296.1|WP_012545679.1|1787844_1788318_+|transcriptional-repressor
MPFGQGWGCRGRFKECGLKWTQTRQAVIDILSSKGGHLSAEEIFLEVKKLLPGIGLATVYRTLELLTELGIVRKFDFKDGRSRYEFVAGKEGIEHYHLICRICGKIIDYETEADKDADPLKDFKKSLSEKFKFSIERSDIQFFGLCERCKGLMEKKD
>NC_011296.1|WP_012545035.1|1788336_1789080_-|sulfite-exporter-TauE/SafE-family-protein
MTYLLASLITFFFTTVLTIAGVGAAFILIPVFVALGIPLLTAMSTALLLNSFAMAVASFYNARAGLIVYRTALPILIIASLLSPLGAITAEHLSRTFLLWLFIGFLLFAGSMMLWYKPKKREISDSKKLISYGAGVGGFAGFIGGLLGVGGGNLIVPALVWLGFDPKKASATTSFIVIFSSFAGFLGHISLGNIDHNLLIVCAIASVAGAVLGNYLMRKKLSAPQVKKVIGIVLYIIAAKMIWDLIK
>NC_011296.1|WP_012545946.1|1789076_1789718_-|formylmethanofuran-dehydrogenase-subunit-E
MIDRETLDKLFGFHGHKCWASALGFRAGQIALENLGVKRANVKELFVILETGYNHGAGCFGDGVQFATGCTAGKGNLIKKPRGKLAFTLIDPKQGKQIRLCFNPKIREKIANSTFMKKRAAGVPPTEISEEEVMEVINLLLESPMEEVLLVGKVEDSYFETPTEVMGMGVCDICGEMVARPYLRLIGKAQACEVVELKKVCIDCSGYEEGFEK
>NC_011296.1|WP_012545318.1|1790309_1791065_+|YebC/PmpR-family-DNA-binding-transcriptional-regulator
MAGHSKWAQIKHKKAQVDAKKGKIFTKLVKEISVAARLGGGDPEKNPRLRVAIEKAREVNMPMDNIKRAIMKGTGELAGTTYEEVIYEGYGPGGVAILIEAMTDNKNRTVSEIRHLLSKHGGSLGESGCVSWIFEKKGYILVDKKTIDEDTLISVALEAGVEDVKNDPKEENYEIIVSPEQLNQVKTIIEKAGIPVSFAQVTMLPKNYISIEGEDAEKMLKLMDALEDHDDVQNVYANFDIPEEAMSKAEV
>NC_011296.1|WP_012546603.1|1791066_1791678_+|DUF502-domain-containing-protein
MEPSIRLTFKRKFIAGLIVTIPVAISIFILIQLFKIIDGLLGPIYDYIFGRHIAGLGFLTALILVFVVGVISTNVFGKKLLDQIEKLLFLKIPIFKSLYSSLKQLIDAFSPENKTSFQKFVIVEYPRKDSFVFGFQTKECILKENDMEKKLIAVYIPTNNLYLGEVVLFEPESVIHTNIPVQEGIKIILSGGIAAPQIIRGDK
>NC_011296.1|WP_012545497.1|1791677_1793036_+|UDP-N-acetylglucosamine-diphosphorylase/glucosamine-1-phosphate-N-acetyltransferase
MDVVILAAGLGTRMKSSKPKVLHRILEKPIIDYVIDCAKSLNPFNSFVVINPSLKEVAEHLEKYNIKIVFQDEPKGTAHALLSALPYLSSDKILILNGDTPLLRKETLDSFIELFNKNGLDMALLSFYPQREHSYGRILRDGEQKIKKIVEITDFKDELMLSSEANSGIYILKREVAELVKEIKQNPNKGEFYLTDIVEIAVNKGFNIEAYPLAEENELIGINTRAELSLAMRYLRDRIVKGWMEKGITFYDPALVWISPSVTIGQDTIIYPNVFLEGDTKIGQNCLICQGVRIKNSIIEDNVQINDCTVIENSHIKSASKIGPFAHLRPDSIIGKGCRIGNFVEVKNSTIGDGTKAAHLSYIGDSEIGNNVNIGAGTITCNYDGQKKHKTIIEDNVFIGSDTQLVAPVKICKGAYIGAGSTITKEVPEDSLAISRTPQKNILGWAKKKRKQ
>NC_011296.1|WP_012545099.1|1793035_1794865_+|glutamine--fructose-6-phosphate-transaminase-(isomerizing)
MCGIIGYIGDKNAIQIVLDGLKKLEYRGYDSAGIACLLNGKIKTVKCKGKIKNLESLVDDSLKQSKIAIGHTRWATHGKPSDENAHPHCSGSIALVHNGIIENYAEIKKELQTEGYKFVSQTDTEVIAHLIRKYRENNLSLEDSIRKAVSRLRGSYAIVIMDDKEPDKLIGVRMESPLVVGISDGEKFIASDVPAFLNHCNKALFLEDGEMIVLNKEGFRVYNLEGKEKKKTPITITWTASMAEKGGFKHFMLKEIYEQPRALSDTIRGRVLSDQGKIVFEEFGLTRDEMRRIEKIYLVACGTSYHACLIGEYIIENIAQIPVEVDIASEFRYRNIPFEKNSLFVAITQSGETADTLAALRYAKKFGVKTLSICNVLGSTASREADAVFYTHSGPEIGVASTKAFTCQIVALYILSIGLSIAKGVFPKIFIKNLLEELLLLPRMAEETLLLDKKIQLLAKEVYRKPNFLYLGRGVNYPVALEGALKLKEISYIHAEGYAAGEMKHGPIALVEEGFPVVFIASDDLYLEKTISNIEEIKARDGFIITISSSKEEKLKKLSDRFIYVEGINSYLNTVLFSIPLQLLAYHVALLRGCDVDQPRNLAKSVTVE
>NC_011296.1|WP_012546392.1|1794901_1797001_+|UvrD-helicase-domain-containing-protein
MKDFPLRDLNPAQQEAVVYCEGPLLVLAGAGSGKTRVITYKYAYLTKSKGLLPSSIFTVTFTNKAADEMKERIFKMCNGNWKNTWIGTFHSLCVRILRAHIDNIGYKRDFIIYDDDDQAGLIKRILKDLNMHEALCKCVVTKISNLKSNLITPEDYISNIEGYEFEERLGRIYMRYQNELKRYNALDFDDLILCVIKLFNENEDLLRRYSEQFKYILVDEFQDTNKSQYMLLQLLCRYHKNICAVGDDDQSIYKFRGANIHNILNFEKDFPDTKIVKLEQNYRSTKHIILASSAMISRNTMRKPKILWTERDWGEKIFYCQLNNEEEEAKYIAKNIKELYLKGDYEYKDFAILYRLVLQARALEEALRMEGIPYQVISGVSFYHRKEIKDVLAYMRFILNKEDNVSLMRIINTPPRGIGASAISKIESEAKKYMISTFEAIKRIIKEDTVSATLKEKLVSFVTLIDELSEKDYKDAASMIKDILNFTGYLEEIEEDRIQNVLEFLSSAEKMPVREFLDKVALFSNVDTWENKKNYVSLLTLHAAKGLEFPVVFIAGCEEGILPYFKALEDPFELQEERRLFYVGMTRAKNLLFITSVKQRKLYSKVQKQETSSFIKDIPPEYCICIRKDYSTFAPNKKEPETSKIKPPFVIGCKVKHPTWGVGVVRDCYGEGDDLKVIVNFPGIGIKKLAPKIVNLERV
>NC_011296.1|WP_012544984.1|1797003_1797291_+|Asp-tRNA(Asn)/Glu-tRNA(Gln)-amidotransferase-subunit-GatC
MKISKEEVKHIAMLSRLELNEEEIGVYQEQLSRILDYIEKLNEIDTTLVEPTSHVIELKNVFRDDNVKGSISRDEALKNAPDQTDKFFRVPKIIE
>NC_011296.1|WP_012546573.1|1797294_1797678_+|aspartate-1-decarboxylase
MLRSFLRAKLHLAKVTEANLFYEGSISVDIELLELAGILPYERVWISNMNNGERFDTYVIPAAKGSRTIGLNGPAAKKAKVGDRIVIFSYGYLLENEIPLHKPKIIILDENNNPVKIYSASIYPESV

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Crispr_ID: NC_011296_5

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_011296_5

1929305-1937222

Unclear

I-A

Consensus_repeat	Method
CTTTATATCCCACATGGTTCAGATGAAAC	PILER-CR
CTTTATATCCCACATGGTTCAGATGAAAC	CRISPRCasFinder
CTTTATATCCCACATGGTTCAGATGAAAC	CRT
CTTTATATCCCACATGGTTCAGATGAAAC	PILER-CR

120 spacers

cas2,cas1,cas4,cas3,cas5,cas7,cas8b2,cas6

The CRISPR arrays of NC_011296_5

>merge|NC_011296|5|1929305-1937222|PILER-CR,CRISPRCasFinder,CRT,PILER-CR
CTTTATATCCCACATGGTTCAGATGAAACAGGATTTAATCTTTTCAAAAATCTGTCTAACCCACTGCTTTATATCCCACATGGTTCAGATGAAACAAGTGTATCCTCATCTTTTCACAATCTGCCTTTATCACTTTATATCCCACATGGTTCAGATGAAACTTCCATCTTCTGTTTGAACCTCTTCCATCTGATAACTTTTATATCCCACATGGTTCAGATGAAACTAAGAACGGTGCTGACTTCACTTACTTCATCTGTCACCTTTATATCCCACATGGTTCAGATGAAACAGAATACAGAGTAATCAATTGCAGATTTCTCCAGACTTTATATCCCACATGGTTCAGATGAAACTTCAGATTCATCAAAGAAAATTTTTGGTGTCATTGCCTTTATATCCCACATGGTTCAGATGAAACATTGAGAAGAAAAGCAGAAAGAGAATTATTTTTAGACTTTATATCCCACATGGTTCAGATGAAACTGGATATTTTTCGCTGGCGTAGGTAATGGCAAGTGCACTTTATATCCCACATGGTTCAGATGAAACGAAAAATACTTTTGGAATTAGCAACTAAATATAACTCTTTATATCCCACATGGTTCAGATGAAACTGAGCGGATATAACTTCATTGAGCTTGCGTGGGGAAGCTTTATATCCCACATGGTTCAGATGAAACTGCTTCTTGCTTAGCTTTCCTTTCTAATTCTAAATCGTCTTTATATCCCACATGGTTCAGATGAAACTATTCTACCCCAAAGATATTCCATTGCGAGGTCTTGCTTTATATCCCACATGGTTCAGATGAAACAAAATATATTTTATAAGTTTATTCCTACCTCCAGTAAACTTTATATCCCACATGGTTCAGATGAAACTTAACCGTGCAATAAACATACTTGTGAACTATACAGTCTTTATATCCCACATGGTTCAGATGAAACCATACCTTTCGTGAGGTGGTAGATGCTAAGGATTATTGCTTTATATCCCACATGGTTCAGATGAAACTCGCAATCCCTCCTGCTATGGTAGTCCCTCCTCTGACTTTATATCCCACATGGTTCAGATGAAACTTTTTTAGCTCTTGTTTGCTCTGTTTTCTTGCTAAGCTTTATATCCCACATGGTTCAGATGAAACACAATATAAATAAGGCAGTTTCTCTTCAGGAAAAAACTTTATATCCCACATGGTTCAGATGAAACACGCATTAATGTTGCTGAACTTGCAAGGGTAATTGGACTTTATATCCCACATGGTTCAGATGAAACTTGAGGATGTCCGTTGGCATGACCTGCGGCGAACATTCTTTATATCCCACATGGTTCAGATGAAACGGGGATTGTGGATTACAGATATGACAGATTCAATCCTTTATATCCCACATGGTTCAGATGAAACAGGGACTAAATCCTCTGGCGGGGTTGTTAAGAAAAACTTTATATCCCACATGGTTCAGATGAAACACAATTAACAAAGAGTACCCCGCCGAACCGAAAACGTCTTTATATCCCACATGGTTCAGATGAAACAGGAAGAAATAGTAAAGATACTGCAGCATACTCCCGGTCTTTATATCCCACATGGTTCAGATGAAACGGTTCTAAAAACAGACAGAAAATTATAGGGCTTATACTTTATATCCCACATGGTTCAGATGAAACTTTTTATAATTTATCAGAACATTACTGCAGGGTATACTTTATATCCCACATGGTTCAGATGAAACATTGAAGGAGTAATAAAAAGATTCTCTGCATCAGGCCTTTATATCCCACATGGTTCAGATGAAACTTTACATAAGTGAATCAAGGGTAATTATTAAAACTGTCTTTATATCCCACATGGTTCAGATGAAACTAGAAAGAAATCAGAAAAAGAAGCTCTATACATACTTTCTTTATATCCCACATGGTTCAGATGAAACGATGAAGAAAAAATTAGACATAGGACAGCTTGACCTGCTTTATATCCCACATGGTTCAGATGAAACGAGGGGAATGTGTTTAAGGGAGCAATTGAAAATACCTGCCTTTATATCCCACATGGTTCAGATGAAACCTTGAGGCTGCCTGTCAGAGGCTTGGCTTGTCTATGCAAGCTTTATATCCCACATGGTTCAGATGAAACTTTAATAAATAATGCTAATATTTCATTAAAAGCAAACTTTATATCCCACATGGTTCAGATGAAACGATGTTAAGAGTAAAAACTCCTATAATTAATCCTGCCTTTATATCCCACATGGTTCAGATGAAACTTCTCTTTGAAGTTCCTATAGAGAGAATTAAATTAACTTTATATCCCACATGGTTCAGATGAAACGCATTATATAGAGAAATTCAGTACCACCGCCTTTGGCTTTATATCCCACATGGTTCAGATGAAACGGAGTTGATGGATTTATATAATTATCAGGACTCGACTTTATATCCCACATGGTTCAGATGAAACAGCATGTATTTGCAAGAAGTGAACAAGAGCTTGAACCTTTATATCCCACATGGTTCAGATGAAACGAATTTGAAGTTGAAATTTCTAATGATGATTTCTTTACTTTATATCCCACATGGTTCAGATGAAACGGCAACCACTGCTGTAAAAGACAAAAAAGTAATCTCTGCTTTATATCCCACATGGTTCAGATGAAACTACTGCTTCTATTGTTATGTAAGCAATTTCTCCAACCTTTATATCCCACATGGTTCAGATGAAACGGCAACCACTGCTGTAAAAGACAAAAAAGTAATCTCTGCTTTATATCCCACATGGTTCAGATGAAACTACTGCTTCTATTGTTATGTAAGCAATTTCTCCAACCTTTATATCCCACATGGTTCAGATGAAACATACTTGTTTTACAGAACACTAAAAAACACAACCGAACTTTATATCCCACATGGTTCAGATGAAACAACATGTCAGTTTTCTCATTGGCTTGAGTATCTTCTACTTTATATCCCACATGGTTCAGATGAAACAGATGTGCTGATGAGCGAGAAAGAGTTTTCAGAGAAGACTTTATATCCCACATGGTTCAGATGAAACGAAGCTAAGAAGGTTGAAGAAAAACCTGCTCAGAAGACTTTATATCCCACATGGTTCAGATGAAACTGTAAAGTAAACTACGTAACGTAGTTTACTTAAAACCTTTATATCCCACATGGTTCAGATGAAACGTTGTTGCCTTGCCTTCGTGCTTTTCAATTTGCACTTCTTTATATCCCACATGGTTCAGATGAAACCAACTGTAACTGTTAAAGATGGTGAAACCACTGCTATTGTCTTTATATCCCACATGGTTCAGATGAAACTCTTTTTTAGAATGAATTCTATAATTCATCATTATATTCTTTATATCCCACATGGTTCAGATGAAACTTAACATCTCCCTTGTCAATCGCAGATACAGGCAACTTTATATCCCACATGGTTCAGATGAAACATGGAAATTTATATGTAATTTTGAAAGTAGTTGCTCTTTATATCCCACATGGTTCAGATGAAACCGTTGATTGCATGTTCTTAAGCACTATCTGCATTGCTTTATATCCCACATGGTTCAGATGAAACATCTATCCCTTTTTCCGCACAGATGCGGGTTCTTGCTTTATATCCCACATGGTTCAGATGAAACATGCCATAAGGGCTGTGGCAATAGTAGATGCACCAATCTTTATATCCCACATGGTTCAGATGAAACTTATACTTATTTTTGGGTTCTTGAAAAACAATCAAGCTTTATATCCCACATGGTTCAGATGAAACATATTTGCCAGAAAAGTTAAAGCAATACCTTATCTCACTTTATATCCCACATGGTTCAGATGAAACTATTACTCTCAACCCAATCACGAATTTGTTCTGTTGTCTTTATATCCCACATGGTTCAGATGAAACTGCTTGAAGAACTGAAAGAACCGGAACCATACTGCACTTTATATCCCACATGGTTCAGATGAAACTGAACCCGTAATTATTCAAGATGCCGCAATATTCTTTCTTTATATCCCACATGGTTCAGATGAAACTGCTTGTTGACCATAACAGAAACTTTTTAGCTCCACACTTTATATCCCACATGGTTCAGATGAAACGAGGGTGAGGACATTTGTATTATTTGATAGAATAAGTCTTTATATCCCACATGGTTCAGATGAAACTTTTTGCATCTATATATGCTGTTTATATAATTTTTAAACTTTATATCCCACATGGTTCAGATGAAACATTCTCATACTCAAAAAGAAAAGCCCTTTCTGGCTCACCATCTCTTTATATCCCACATGGTTCAGATGAAACAATTTTATACTTTGCAAATTCTGTTTTTTATGTTTGCTTTATATCCCACATGGTTCAGATGAAACGAATTCATGAAAAAATGCCAGAAAGCTAAATCTTTGATCTTTATATCCCACATGGTTCAGATGAAACGAGTCCATACTGTGTTGGGCAGTATAAAGAGCTCCGCTTTATATCCCACATGGTTCAGATGAAACGCCATTTTTTTGTTTAGATTTCAACTTCAAAGTCTTCCTTTATATCCCACATGGTTCAGATGAAACTAATATTGACAAACTTGAAAATGCAAGATGTATGATGCCTTTATATCCCACATGGTTCAGATGAAACTATGATGCTGGACCTGATAAAACATTTAGAAAGCACTTTATATCCCACATGGTTCAGATGAAACGTTCAACAAACTCTTTGTGTTTGATTTTATTGACAACTTTATATCCCACATGGTTCAGATGAAACGAGACCAGATACAAGAGCATTAGGAATAGCATTAAGACTTTATATCCCACATGGTTCAGATGAAACGAAAACCACGTTTTGACAATAGAAGGTCTTACAAAACTTTATATCCCACATGGTTCAGATGAAACAAATCATCATAACCTTCTGAAGCACTTCTGGAACTGTCTTTATATCCCACATGGTTCAGATGAAACAAGTTTCTTAACTTAGTATAAAAATTATCACAAATAAATTCCTTTATATCCCACATGGTTCAGATGAAACCCGTTGGTAGTGGAGACAGGCTTTGTTGGAAGTTTGACTTTATATCCCACATGGTTCAGATGAAACATCACATATGCAAAAAGATACGCATTGTCTTTAGCTCTCTTTATATCCCACATGGTTCAGATGAAACGATGCAAAAGGATGTTACAGAAAATATGTTAAAAAACTTTATATCCCACATGGTTCAGATGAAACCAACGGGACAGAATGTTACTGTTGATGAAGTTGAGATCTTTATATCCCACATGGTTCAGATGAAACATTTCAAGTTCTAAATCCTTAAAATACCTTGTATCTATCTTTATATCCCACATGGTTCAGATGAAACACAATAAAAGATCCAAGTTGCTGTTGCGTTAAAACACTTTATATCCCACATGGTTCAGATGAAACATAGTCTTTGCCAAAAAGTGTGGCTTTACCAATATCTTTATATCCCACATGGTTCAGATGAAACGTTATAAAGCATATTGTTATGTCTCTGAACTTCTTTCTTTATATCCCACATGGTTCAGATGAAACTCACATATGCAAAAAGATACGCATTGTCTTTAGCTCTCTTTATATCCCACATGGTTCAGATGAAACAGTGAACTTTGTTAGACAAATCTAACTTAGTGAGTGACTTTATATCCCACATGGTTCAGATGAAACGTAGACCCATCGCCACATATGTCTCCAATTCAACAATACTTTATATCCCACATGGTTCAGATGAAACTGAAATTCCTAAAGACAAAATCATCTATAACAAAGACTTTATATCCCACATGGTTCAGATGAAACGTATGTATCGGCTTTATTGCAATCAATATCTTACACTTTATATCCCACATGGTTCAGATGAAACGTTGCAAGAGCTTTTATCCCAACCAGAGCTAATCTCTTTATATCCCACATGGTTCAGATGAAACTGAATGCTTGAGATATTTAGTTTATAACCGAACAAGACTTTATATCCCACATGGTTCAGATGAAACTGTTGCGTTCAAAATCTCTACTTCTTTCTCTAAGCGTCTTTATATCCCACATGGTTCAGATGAAACCCTGAGTTAGTTGAGGCGGGGAGAGGGGTCCTTCCTACTTTATATCCCACATGGTTCAGATGAAACTTAAACGAATGGAATGAGACAATGATAAAGCGATACCTTTATATCCCACATGGTTCAGATGAAACTGTGTATGCCAGAAGAAATTGTTTCGGCATTTTCTTCTTTATATCCCACATGGTTCAGATGAAACTATCAGCAGTTCGTCAAGTTTAATGTTTTTAACAGACTTTATATCCCACATGGTTCAGATGAAACAATATCAAATTTATTACTCAACCAGCAAGGACAATAATAACCTTTATATCCCACATGGTTCAGATGAAACACTGTACTGACACAACAGCGGAAATAACAAACTACAACTTTATATCCCACATGGTTCAGATGAAACCTCTTCTATGTTTTTGTCTTTGACATTAACCCCTTCCTTTATATCCCACATGGTTCAGATGAAACTTTGTTTTTTGATAAGTTACTATTTTCGTTGTTATCTTTATATCCCACATGGTTCAGATGAAACTGCATCTGCAGGAATGCTTACAAGAGATATTTCAAGCTTTATATCCCACATGGTTCAGATGAAACTAACTTTCCCTGAAAGTGCTGACATTTGAACCCATACCTTTATATCCCACATGGTTCAGATGAAACTTATACTGCTCTACTGCATCGTAGGCAAGTCTAAATACTTTATATCCCACATGGTTCAGATGAAACTCCCATCCTGCCCTGGCAAATTCTCTATAACATAAACCTTTATATCCCACATGGTTCAGATGAAACTCCTGCAAAAATCAATCTTCTTAAAATTACTGCTTTCTTTATATCCCACATGGTTCAGATGAAACCTTGTTTTTACATCGTGAACCTTCCCCTTGAAACACTTTATATCCCACATGGTTCAGATGAAACTGGTGCAGGTGGCTCTGGTGGAGCTGCGGGCTCTGCCTTTATATCCCACATGGTTCAGATGAAACTCGTCCGCCCACTCGCTTACCGTCTGCTTTGGTCTCTTTATATCCCACATGGTTCAGATGAAACAACTTCATCCCATGCAAGCCCTCCAGGATGGAATCTCTTTATATCCCACATGGTTCAGATGAAACTAAAAGCTATTCTGACATCTTTGGCAGTTTTTTCTGAACTTTATATCCCACATGGTTCAGATGAAACAACTTCAACTGGGCACATATTCCAGATGCAGACTTACTTTATATCCCACATGGTTCAGATGAAACAAAATTTCCAAACTGCCAAAAACCTTTATTTTTTCACTTTATATCCCACATGGTTCAGATGAAACAGACAGGCTTTGTTGGAAGTTTGACGGGGAGAGTATTCTTTATATCCCACATGGTTCAGATGAAACGACCTTGATAGAAAAATCACTATTACCACAAGACCTCCTTTATATCCCACATGGTTCAGATGAAACTTTGCTCCCTTTTTCGCACAAATTGGGCAACTGGTAGGTACTTTATATCCCACATGGTTCAGATGAAACTTGGCACACATATCAGATATTCACCATCTTTGATTGTCTTTATATCCCACATGGTTCAGATGAAACAAGCTGGATGCTTGACTTCACAGTCACTGAACCATCCTTTATATCCCACATGGTTCAGATGAAACCTGGTGGATTATCACGCTTCTGGTTGGCAATTTAGTCCTTTATATCCCACATGGTTCAGATGAAACATGAAATCCTCAGTAGGAACAAAGATGCCCCCACACCTTTATATCCCACATGGTTCAGATGAAACGATGCTGGACCTGCAAACATTGTTGAGGCTATTGGCTTTATATCCCACATGGTTCAGATGAAAC

>NC_011296|5|4|1929305-1933472|PILER-CR
CTTTATATCCCACATGGTTCAGATGAAAC	AGGATTTAATCTTTTCAAAAATCTGTCTAACCCACTG
CTTTATATCCCACATGGTTCAGATGAAAC	AAGTGTATCCTCATCTTTTCACAATCTGCCTTTATCA
CTTTATATCCCACATGGTTCAGATGAAAC	TTCCATCTTCTGTTTGAACCTCTTCCATCTGATAAC
TTTTATATCCCACATGGTTCAGATGAAAC	TAAGAACGGTGCTGACTTCACTTACTTCATCTGTCAC
CTTTATATCCCACATGGTTCAGATGAAAC	AGAATACAGAGTAATCAATTGCAGATTTCTCCAGA
CTTTATATCCCACATGGTTCAGATGAAAC	TTCAGATTCATCAAAGAAAATTTTTGGTGTCATTGC
CTTTATATCCCACATGGTTCAGATGAAAC	ATTGAGAAGAAAAGCAGAAAGAGAATTATTTTTAGA
CTTTATATCCCACATGGTTCAGATGAAAC	TGGATATTTTTCGCTGGCGTAGGTAATGGCAAGTGCA
CTTTATATCCCACATGGTTCAGATGAAAC	GAAAAATACTTTTGGAATTAGCAACTAAATATAACT
CTTTATATCCCACATGGTTCAGATGAAAC	TGAGCGGATATAACTTCATTGAGCTTGCGTGGGGAAG
CTTTATATCCCACATGGTTCAGATGAAAC	TGCTTCTTGCTTAGCTTTCCTTTCTAATTCTAAATCGT
CTTTATATCCCACATGGTTCAGATGAAAC	TATTCTACCCCAAAGATATTCCATTGCGAGGTCTTG
CTTTATATCCCACATGGTTCAGATGAAAC	AAAATATATTTTATAAGTTTATTCCTACCTCCAGTAAA
CTTTATATCCCACATGGTTCAGATGAAAC	TTAACCGTGCAATAAACATACTTGTGAACTATACAGT
CTTTATATCCCACATGGTTCAGATGAAAC	CATACCTTTCGTGAGGTGGTAGATGCTAAGGATTATTG
CTTTATATCCCACATGGTTCAGATGAAAC	TCGCAATCCCTCCTGCTATGGTAGTCCCTCCTCTGA
CTTTATATCCCACATGGTTCAGATGAAAC	TTTTTTAGCTCTTGTTTGCTCTGTTTTCTTGCTAAG
CTTTATATCCCACATGGTTCAGATGAAAC	ACAATATAAATAAGGCAGTTTCTCTTCAGGAAAAAA
CTTTATATCCCACATGGTTCAGATGAAAC	ACGCATTAATGTTGCTGAACTTGCAAGGGTAATTGGA
CTTTATATCCCACATGGTTCAGATGAAAC	TTGAGGATGTCCGTTGGCATGACCTGCGGCGAACATT
CTTTATATCCCACATGGTTCAGATGAAAC	GGGGATTGTGGATTACAGATATGACAGATTCAATC
CTTTATATCCCACATGGTTCAGATGAAAC	AGGGACTAAATCCTCTGGCGGGGTTGTTAAGAAAAA
CTTTATATCCCACATGGTTCAGATGAAAC	ACAATTAACAAAGAGTACCCCGCCGAACCGAAAACGT
CTTTATATCCCACATGGTTCAGATGAAAC	AGGAAGAAATAGTAAAGATACTGCAGCATACTCCCGGT
CTTTATATCCCACATGGTTCAGATGAAAC	GGTTCTAAAAACAGACAGAAAATTATAGGGCTTATA
CTTTATATCCCACATGGTTCAGATGAAAC	TTTTTATAATTTATCAGAACATTACTGCAGGGTATA
CTTTATATCCCACATGGTTCAGATGAAAC	ATTGAAGGAGTAATAAAAAGATTCTCTGCATCAGGC
CTTTATATCCCACATGGTTCAGATGAAAC	TTTACATAAGTGAATCAAGGGTAATTATTAAAACTGT
CTTTATATCCCACATGGTTCAGATGAAAC	TAGAAAGAAATCAGAAAAAGAAGCTCTATACATACTTT
CTTTATATCCCACATGGTTCAGATGAAAC	GATGAAGAAAAAATTAGACATAGGACAGCTTGACCTG
CTTTATATCCCACATGGTTCAGATGAAAC	GAGGGGAATGTGTTTAAGGGAGCAATTGAAAATACCTGC
CTTTATATCCCACATGGTTCAGATGAAAC	CTTGAGGCTGCCTGTCAGAGGCTTGGCTTGTCTATGCAAG
CTTTATATCCCACATGGTTCAGATGAAAC	TTTAATAAATAATGCTAATATTTCATTAAAAGCAAA
CTTTATATCCCACATGGTTCAGATGAAAC	GATGTTAAGAGTAAAAACTCCTATAATTAATCCTGC
CTTTATATCCCACATGGTTCAGATGAAAC	TTCTCTTTGAAGTTCCTATAGAGAGAATTAAATTAA
CTTTATATCCCACATGGTTCAGATGAAAC	GCATTATATAGAGAAATTCAGTACCACCGCCTTTGG
CTTTATATCCCACATGGTTCAGATGAAAC	GGAGTTGATGGATTTATATAATTATCAGGACTCGA
CTTTATATCCCACATGGTTCAGATGAAAC	AGCATGTATTTGCAAGAAGTGAACAAGAGCTTGAAC
CTTTATATCCCACATGGTTCAGATGAAAC	GAATTTGAAGTTGAAATTTCTAATGATGATTTCTTTA
CTTTATATCCCACATGGTTCAGATGAAAC	GGCAACCACTGCTGTAAAAGACAAAAAAGTAATCTCTG
CTTTATATCCCACATGGTTCAGATGAAAC	TACTGCTTCTATTGTTATGTAAGCAATTTCTCCAAC
CTTTATATCCCACATGGTTCAGATGAAAC	GGCAACCACTGCTGTAAAAGACAAAAAAGTAATCTCTG
CTTTATATCCCACATGGTTCAGATGAAAC	TACTGCTTCTATTGTTATGTAAGCAATTTCTCCAAC
CTTTATATCCCACATGGTTCAGATGAAAC	ATACTTGTTTTACAGAACACTAAAAAACACAACCGAA
CTTTATATCCCACATGGTTCAGATGAAAC	AACATGTCAGTTTTCTCATTGGCTTGAGTATCTTCTA
CTTTATATCCCACATGGTTCAGATGAAAC	AGATGTGCTGATGAGCGAGAAAGAGTTTTCAGAGAAGA
CTTTATATCCCACATGGTTCAGATGAAAC	GAAGCTAAGAAGGTTGAAGAAAAACCTGCTCAGAAGA
CTTTATATCCCACATGGTTCAGATGAAAC	TGTAAAGTAAACTACGTAACGTAGTTTACTTAAAAC
CTTTATATCCCACATGGTTCAGATGAAAC	GTTGTTGCCTTGCCTTCGTGCTTTTCAATTTGCACTT
CTTTATATCCCACATGGTTCAGATGAAAC	CAACTGTAACTGTTAAAGATGGTGAAACCACTGCTATTGT
CTTTATATCCCACATGGTTCAGATGAAAC	TCTTTTTTAGAATGAATTCTATAATTCATCATTATATT
CTTTATATCCCACATGGTTCAGATGAAAC	TTAACATCTCCCTTGTCAATCGCAGATACAGGCAA
CTTTATATCCCACATGGTTCAGATGAAAC	ATGGAAATTTATATGTAATTTTGAAAGTAGTTGCT
CTTTATATCCCACATGGTTCAGATGAAAC	CGTTGATTGCATGTTCTTAAGCACTATCTGCATTG
CTTTATATCCCACATGGTTCAGATGAAAC	ATCTATCCCTTTTTCCGCACAGATGCGGGTTCTTG
CTTTATATCCCACATGGTTCAGATGAAAC	ATGCCATAAGGGCTGTGGCAATAGTAGATGCACCAAT
CTTTATATCCCACATGGTTCAGATGAAAC	TTATACTTATTTTTGGGTTCTTGAAAAACAATCAAG
CTTTATATCCCACATGGTTCAGATGAAAC	ATATTTGCCAGAAAAGTTAAAGCAATACCTTATCTCA
CTTTATATCCCACATGGTTCAGATGAAAC	TATTACTCTCAACCCAATCACGAATTTGTTCTGTTGT
CTTTATATCCCACATGGTTCAGATGAAAC	TGCTTGAAGAACTGAAAGAACCGGAACCATACTGCA
CTTTATATCCCACATGGTTCAGATGAAAC	TGAACCCGTAATTATTCAAGATGCCGCAATATTCTTT
CTTTATATCCCACATGGTTCAGATGAAAC	TGCTTGTTGACCATAACAGAAACTTTTTAGCTCCACA
CTTTATATCCCACATGGTTCAGATGAAAC	GAGGGTGAGGACATTTGTATTATTTGATAGAATAAGT
CTTTATATCCCACATGGTTCAGATGAAACTTTTTGCATCTATATATGCTGTTTATATAATTTTTAAACTTTATATCCCACATGGTTCAGATGAAAC	ATTCTCATACTCAAAAAGAAAAGCCCTTTCTGGCTCACCATCT
CTTTATATCCCACATGGTTCAGATGAAAC	AATTTTATACTTTGCAAATTCTGTTTTTTATGTTTG
CTTTATATCCCACATGGTTCAGATGAAAC	GAATTCATGAAAAAATGCCAGAAAGCTAAATCTTTGAT
CTTTATATCCCACATGGTTCAGATGAAAC	GAGTCCATACTGTGTTGGGCAGTATAAAGAGCTCCG
CTTTATATCCCACATGGTTCAGATGAAAC	GCCATTTTTTTGTTTAGATTTCAACTTCAAAGTCTTC
CTTTATATCCCACATGGTTCAGATGAAAC	TAATATTGACAAACTTGAAAATGCAAGATGTATGATGC
CTTTATATCCCACATGGTTCAGATGAAAC	TATGATGCTGGACCTGATAAAACATTTAGAAAGCA
CTTTATATCCCACATGGTTCAGATGAAAC	GTTCAACAAACTCTTTGTGTTTGATTTTATTGACAA
CTTTATATCCCACATGGTTCAGATGAAAC	GAGACCAGATACAAGAGCATTAGGAATAGCATTAAGA
CTTTATATCCCACATGGTTCAGATGAAAC	GAAAACCACGTTTTGACAATAGAAGGTCTTACAAAA
CTTTATATCCCACATGGTTCAGATGAAAC	AAATCATCATAACCTTCTGAAGCACTTCTGGAACTGT
CTTTATATCCCACATGGTTCAGATGAAAC	AAGTTTCTTAACTTAGTATAAAAATTATCACAAATAAATTC
CTTTATATCCCACATGGTTCAGATGAAAC	CCGTTGGTAGTGGAGACAGGCTTTGTTGGAAGTTTGA
CTTTATATCCCACATGGTTCAGATGAAAC	ATCACATATGCAAAAAGATACGCATTGTCTTTAGCTCT
CTTTATATCCCACATGGTTCAGATGAAAC	GATGCAAAAGGATGTTACAGAAAATATGTTAAAAAA
CTTTATATCCCACATGGTTCAGATGAAAC	CAACGGGACAGAATGTTACTGTTGATGAAGTTGAGAT
CTTTATATCCCACATGGTTCAGATGAAAC	ATTTCAAGTTCTAAATCCTTAAAATACCTTGTATCTAT
CTTTATATCCCACATGGTTCAGATGAAAC	ACAATAAAAGATCCAAGTTGCTGTTGCGTTAAAACA
CTTTATATCCCACATGGTTCAGATGAAAC	ATAGTCTTTGCCAAAAAGTGTGGCTTTACCAATAT
CTTTATATCCCACATGGTTCAGATGAAAC	GTTATAAAGCATATTGTTATGTCTCTGAACTTCTTT
CTTTATATCCCACATGGTTCAGATGAAAC	TCACATATGCAAAAAGATACGCATTGTCTTTAGCTCT
CTTTATATCCCACATGGTTCAGATGAAAC	AGTGAACTTTGTTAGACAAATCTAACTTAGTGAGTGA
CTTTATATCCCACATGGTTCAGATGAAAC	GTAGACCCATCGCCACATATGTCTCCAATTCAACAATA
CTTTATATCCCACATGGTTCAGATGAAAC	TGAAATTCCTAAAGACAAAATCATCTATAACAAAGA
CTTTATATCCCACATGGTTCAGATGAAAC	GTATGTATCGGCTTTATTGCAATCAATATCTTACA
CTTTATATCCCACATGGTTCAGATGAAAC	GTTGCAAGAGCTTTTATCCCAACCAGAGCTAATCT
CTTTATATCCCACATGGTTCAGATGAAAC	TGAATGCTTGAGATATTTAGTTTATAACCGAACAAGA
CTTTATATCCCACATGGTTCAGATGAAAC	TGTTGCGTTCAAAATCTCTACTTCTTTCTCTAAGCGT
CTTTATATCCCACATGGTTCAGATGAAAC	CCTGAGTTAGTTGAGGCGGGGAGAGGGGTCCTTCCTA
CTTTATATCCCACATGGTTCAGATGAAAC	TTAAACGAATGGAATGAGACAATGATAAAGCGATAC
CTTTATATCCCACATGGTTCAGATGAAAC	TGTGTATGCCAGAAGAAATTGTTTCGGCATTTTCTT
CTTTATATCCCACATGGTTCAGATGAAAC	TATCAGCAGTTCGTCAAGTTTAATGTTTTTAACAGA
CTTTATATCCCACATGGTTCAGATGAAAC	AATATCAAATTTATTACTCAACCAGCAAGGACAATAATAAC
CTTTATATCCCACATGGTTCAGATGAAAC	ACTGTACTGACACAACAGCGGAAATAACAAACTACAA
CTTTATATCCCACATGGTTCAGATGAAAC	CTCTTCTATGTTTTTGTCTTTGACATTAACCCCTTC
CTTTATATCCCACATGGTTCAGATGAAAC	TTTGTTTTTTGATAAGTTACTATTTTCGTTGTTAT
CTTTATATCCCACATGGTTCAGATGAAAC	TGCATCTGCAGGAATGCTTACAAGAGATATTTCAAG
CTTTATATCCCACATGGTTCAGATGAAAC	TAACTTTCCCTGAAAGTGCTGACATTTGAACCCATAC
CTTTATATCCCACATGGTTCAGATGAAAC	TTATACTGCTCTACTGCATCGTAGGCAAGTCTAAATA
CTTTATATCCCACATGGTTCAGATGAAAC	TCCCATCCTGCCCTGGCAAATTCTCTATAACATAAAC
CTTTATATCCCACATGGTTCAGATGAAAC	TCCTGCAAAAATCAATCTTCTTAAAATTACTGCTTT
CTTTATATCCCACATGGTTCAGATGAAAC	CTTGTTTTTACATCGTGAACCTTCCCCTTGAAACA
CTTTATATCCCACATGGTTCAGATGAAAC	TGGTGCAGGTGGCTCTGGTGGAGCTGCGGGCTCTGC
CTTTATATCCCACATGGTTCAGATGAAAC	TCGTCCGCCCACTCGCTTACCGTCTGCTTTGGTCT
CTTTATATCCCACATGGTTCAGATGAAAC	AACTTCATCCCATGCAAGCCCTCCAGGATGGAATCT
CTTTATATCCCACATGGTTCAGATGAAAC	TAAAAGCTATTCTGACATCTTTGGCAGTTTTTTCTGAA
CTTTATATCCCACATGGTTCAGATGAAAC	AACTTCAACTGGGCACATATTCCAGATGCAGACTTA
CTTTATATCCCACATGGTTCAGATGAAAC	AAAATTTCCAAACTGCCAAAAACCTTTATTTTTTCA
CTTTATATCCCACATGGTTCAGATGAAAC	AGACAGGCTTTGTTGGAAGTTTGACGGGGAGAGTATT
CTTTATATCCCACATGGTTCAGATGAAAC	GACCTTGATAGAAAAATCACTATTACCACAAGACCTC
CTTTATATCCCACATGGTTCAGATGAAAC	TTTGCTCCCTTTTTCGCACAAATTGGGCAACTGGTAGGTA
CTTTATATCCCACATGGTTCAGATGAAAC	TTGGCACACATATCAGATATTCACCATCTTTGATTGT
CTTTATATCCCACATGGTTCAGATGAAAC	AAGCTGGATGCTTGACTTCACAGTCACTGAACCATC
CTTTATATCCCACATGGTTCAGATGAAAC	CTGGTGGATTATCACGCTTCTGGTTGGCAATTTAGTC
CTTTATATCCCACATGGTTCAGATGAAAC	ATGAAATCCTCAGTAGGAACAAAGATGCCCCCACAC
CTTTATATCCCACATGGTTCAGATGAAAC	GATGCTGGACCTGCAAACATTGTTGAGGCTATTGG


>NC_011296|5|5|1929305-1937222|CRISPRCasFinder
CTTTATATCCCACATGGTTCAGATGAAAC	AGGATTTAATCTTTTCAAAAATCTGTCTAACCCACTG
CTTTATATCCCACATGGTTCAGATGAAAC	AAGTGTATCCTCATCTTTTCACAATCTGCCTTTATCA
CTTTATATCCCACATGGTTCAGATGAAAC	TTCCATCTTCTGTTTGAACCTCTTCCATCTGATAAC
TTTTATATCCCACATGGTTCAGATGAAAC	TAAGAACGGTGCTGACTTCACTTACTTCATCTGTCAC
CTTTATATCCCACATGGTTCAGATGAAAC	AGAATACAGAGTAATCAATTGCAGATTTCTCCAGA
CTTTATATCCCACATGGTTCAGATGAAAC	TTCAGATTCATCAAAGAAAATTTTTGGTGTCATTGC
CTTTATATCCCACATGGTTCAGATGAAAC	ATTGAGAAGAAAAGCAGAAAGAGAATTATTTTTAGA
CTTTATATCCCACATGGTTCAGATGAAAC	TGGATATTTTTCGCTGGCGTAGGTAATGGCAAGTGCA
CTTTATATCCCACATGGTTCAGATGAAAC	GAAAAATACTTTTGGAATTAGCAACTAAATATAACT
CTTTATATCCCACATGGTTCAGATGAAAC	TGAGCGGATATAACTTCATTGAGCTTGCGTGGGGAAG
CTTTATATCCCACATGGTTCAGATGAAAC	TGCTTCTTGCTTAGCTTTCCTTTCTAATTCTAAATCGT
CTTTATATCCCACATGGTTCAGATGAAAC	TATTCTACCCCAAAGATATTCCATTGCGAGGTCTTG
CTTTATATCCCACATGGTTCAGATGAAAC	AAAATATATTTTATAAGTTTATTCCTACCTCCAGTAAA
CTTTATATCCCACATGGTTCAGATGAAAC	TTAACCGTGCAATAAACATACTTGTGAACTATACAGT
CTTTATATCCCACATGGTTCAGATGAAAC	CATACCTTTCGTGAGGTGGTAGATGCTAAGGATTATTG
CTTTATATCCCACATGGTTCAGATGAAAC	TCGCAATCCCTCCTGCTATGGTAGTCCCTCCTCTGA
CTTTATATCCCACATGGTTCAGATGAAAC	TTTTTTAGCTCTTGTTTGCTCTGTTTTCTTGCTAAG
CTTTATATCCCACATGGTTCAGATGAAAC	ACAATATAAATAAGGCAGTTTCTCTTCAGGAAAAAA
CTTTATATCCCACATGGTTCAGATGAAAC	ACGCATTAATGTTGCTGAACTTGCAAGGGTAATTGGA
CTTTATATCCCACATGGTTCAGATGAAAC	TTGAGGATGTCCGTTGGCATGACCTGCGGCGAACATT
CTTTATATCCCACATGGTTCAGATGAAAC	GGGGATTGTGGATTACAGATATGACAGATTCAATC
CTTTATATCCCACATGGTTCAGATGAAAC	AGGGACTAAATCCTCTGGCGGGGTTGTTAAGAAAAA
CTTTATATCCCACATGGTTCAGATGAAAC	ACAATTAACAAAGAGTACCCCGCCGAACCGAAAACGT
CTTTATATCCCACATGGTTCAGATGAAAC	AGGAAGAAATAGTAAAGATACTGCAGCATACTCCCGGT
CTTTATATCCCACATGGTTCAGATGAAAC	GGTTCTAAAAACAGACAGAAAATTATAGGGCTTATA
CTTTATATCCCACATGGTTCAGATGAAAC	TTTTTATAATTTATCAGAACATTACTGCAGGGTATA
CTTTATATCCCACATGGTTCAGATGAAAC	ATTGAAGGAGTAATAAAAAGATTCTCTGCATCAGGC
CTTTATATCCCACATGGTTCAGATGAAAC	TTTACATAAGTGAATCAAGGGTAATTATTAAAACTGT
CTTTATATCCCACATGGTTCAGATGAAAC	TAGAAAGAAATCAGAAAAAGAAGCTCTATACATACTTT
CTTTATATCCCACATGGTTCAGATGAAAC	GATGAAGAAAAAATTAGACATAGGACAGCTTGACCTG
CTTTATATCCCACATGGTTCAGATGAAAC	GAGGGGAATGTGTTTAAGGGAGCAATTGAAAATACCTGC
CTTTATATCCCACATGGTTCAGATGAAAC	CTTGAGGCTGCCTGTCAGAGGCTTGGCTTGTCTATGCAAG
CTTTATATCCCACATGGTTCAGATGAAAC	TTTAATAAATAATGCTAATATTTCATTAAAAGCAAA
CTTTATATCCCACATGGTTCAGATGAAAC	GATGTTAAGAGTAAAAACTCCTATAATTAATCCTGC
CTTTATATCCCACATGGTTCAGATGAAAC	TTCTCTTTGAAGTTCCTATAGAGAGAATTAAATTAA
CTTTATATCCCACATGGTTCAGATGAAAC	GCATTATATAGAGAAATTCAGTACCACCGCCTTTGG
CTTTATATCCCACATGGTTCAGATGAAAC	GGAGTTGATGGATTTATATAATTATCAGGACTCGA
CTTTATATCCCACATGGTTCAGATGAAAC	AGCATGTATTTGCAAGAAGTGAACAAGAGCTTGAAC
CTTTATATCCCACATGGTTCAGATGAAAC	GAATTTGAAGTTGAAATTTCTAATGATGATTTCTTTA
CTTTATATCCCACATGGTTCAGATGAAAC	GGCAACCACTGCTGTAAAAGACAAAAAAGTAATCTCTG
CTTTATATCCCACATGGTTCAGATGAAAC	TACTGCTTCTATTGTTATGTAAGCAATTTCTCCAAC
CTTTATATCCCACATGGTTCAGATGAAAC	GGCAACCACTGCTGTAAAAGACAAAAAAGTAATCTCTG
CTTTATATCCCACATGGTTCAGATGAAAC	TACTGCTTCTATTGTTATGTAAGCAATTTCTCCAAC
CTTTATATCCCACATGGTTCAGATGAAAC	ATACTTGTTTTACAGAACACTAAAAAACACAACCGAA
CTTTATATCCCACATGGTTCAGATGAAAC	AACATGTCAGTTTTCTCATTGGCTTGAGTATCTTCTA
CTTTATATCCCACATGGTTCAGATGAAAC	AGATGTGCTGATGAGCGAGAAAGAGTTTTCAGAGAAGA
CTTTATATCCCACATGGTTCAGATGAAAC	GAAGCTAAGAAGGTTGAAGAAAAACCTGCTCAGAAGA
CTTTATATCCCACATGGTTCAGATGAAAC	TGTAAAGTAAACTACGTAACGTAGTTTACTTAAAAC
CTTTATATCCCACATGGTTCAGATGAAAC	GTTGTTGCCTTGCCTTCGTGCTTTTCAATTTGCACTT
CTTTATATCCCACATGGTTCAGATGAAAC	CAACTGTAACTGTTAAAGATGGTGAAACCACTGCTATTGT
CTTTATATCCCACATGGTTCAGATGAAAC	TCTTTTTTAGAATGAATTCTATAATTCATCATTATATT
CTTTATATCCCACATGGTTCAGATGAAAC	TTAACATCTCCCTTGTCAATCGCAGATACAGGCAA
CTTTATATCCCACATGGTTCAGATGAAAC	ATGGAAATTTATATGTAATTTTGAAAGTAGTTGCT
CTTTATATCCCACATGGTTCAGATGAAAC	CGTTGATTGCATGTTCTTAAGCACTATCTGCATTG
CTTTATATCCCACATGGTTCAGATGAAAC	ATCTATCCCTTTTTCCGCACAGATGCGGGTTCTTG
CTTTATATCCCACATGGTTCAGATGAAAC	ATGCCATAAGGGCTGTGGCAATAGTAGATGCACCAAT
CTTTATATCCCACATGGTTCAGATGAAAC	TTATACTTATTTTTGGGTTCTTGAAAAACAATCAAG
CTTTATATCCCACATGGTTCAGATGAAAC	ATATTTGCCAGAAAAGTTAAAGCAATACCTTATCTCA
CTTTATATCCCACATGGTTCAGATGAAAC	TATTACTCTCAACCCAATCACGAATTTGTTCTGTTGT
CTTTATATCCCACATGGTTCAGATGAAAC	TGCTTGAAGAACTGAAAGAACCGGAACCATACTGCA
CTTTATATCCCACATGGTTCAGATGAAAC	TGAACCCGTAATTATTCAAGATGCCGCAATATTCTTT
CTTTATATCCCACATGGTTCAGATGAAAC	TGCTTGTTGACCATAACAGAAACTTTTTAGCTCCACA
CTTTATATCCCACATGGTTCAGATGAAAC	GAGGGTGAGGACATTTGTATTATTTGATAGAATAAGT
CTTTATATCCCACATGGTTCAGATGAAAC	TTTTTGCATCTATATATGCTGTTTATATAATTTTTAAA
CTTTATATCCCACATGGTTCAGATGAAAC	ATTCTCATACTCAAAAAGAAAAGCCCTTTCTGGCTCACCATCT
CTTTATATCCCACATGGTTCAGATGAAAC	AATTTTATACTTTGCAAATTCTGTTTTTTATGTTTG
CTTTATATCCCACATGGTTCAGATGAAAC	GAATTCATGAAAAAATGCCAGAAAGCTAAATCTTTGAT
CTTTATATCCCACATGGTTCAGATGAAAC	GAGTCCATACTGTGTTGGGCAGTATAAAGAGCTCCG
CTTTATATCCCACATGGTTCAGATGAAAC	GCCATTTTTTTGTTTAGATTTCAACTTCAAAGTCTTC
CTTTATATCCCACATGGTTCAGATGAAAC	TAATATTGACAAACTTGAAAATGCAAGATGTATGATGC
CTTTATATCCCACATGGTTCAGATGAAAC	TATGATGCTGGACCTGATAAAACATTTAGAAAGCA
CTTTATATCCCACATGGTTCAGATGAAAC	GTTCAACAAACTCTTTGTGTTTGATTTTATTGACAA
CTTTATATCCCACATGGTTCAGATGAAAC	GAGACCAGATACAAGAGCATTAGGAATAGCATTAAGA
CTTTATATCCCACATGGTTCAGATGAAAC	GAAAACCACGTTTTGACAATAGAAGGTCTTACAAAA
CTTTATATCCCACATGGTTCAGATGAAAC	AAATCATCATAACCTTCTGAAGCACTTCTGGAACTGT
CTTTATATCCCACATGGTTCAGATGAAAC	AAGTTTCTTAACTTAGTATAAAAATTATCACAAATAAATTC
CTTTATATCCCACATGGTTCAGATGAAAC	CCGTTGGTAGTGGAGACAGGCTTTGTTGGAAGTTTGA
CTTTATATCCCACATGGTTCAGATGAAAC	ATCACATATGCAAAAAGATACGCATTGTCTTTAGCTCT
CTTTATATCCCACATGGTTCAGATGAAAC	GATGCAAAAGGATGTTACAGAAAATATGTTAAAAAA
CTTTATATCCCACATGGTTCAGATGAAAC	CAACGGGACAGAATGTTACTGTTGATGAAGTTGAGAT
CTTTATATCCCACATGGTTCAGATGAAAC	ATTTCAAGTTCTAAATCCTTAAAATACCTTGTATCTAT
CTTTATATCCCACATGGTTCAGATGAAAC	ACAATAAAAGATCCAAGTTGCTGTTGCGTTAAAACA
CTTTATATCCCACATGGTTCAGATGAAAC	ATAGTCTTTGCCAAAAAGTGTGGCTTTACCAATAT
CTTTATATCCCACATGGTTCAGATGAAAC	GTTATAAAGCATATTGTTATGTCTCTGAACTTCTTT
CTTTATATCCCACATGGTTCAGATGAAAC	TCACATATGCAAAAAGATACGCATTGTCTTTAGCTCT
CTTTATATCCCACATGGTTCAGATGAAAC	AGTGAACTTTGTTAGACAAATCTAACTTAGTGAGTGA
CTTTATATCCCACATGGTTCAGATGAAAC	GTAGACCCATCGCCACATATGTCTCCAATTCAACAATA
CTTTATATCCCACATGGTTCAGATGAAAC	TGAAATTCCTAAAGACAAAATCATCTATAACAAAGA
CTTTATATCCCACATGGTTCAGATGAAAC	GTATGTATCGGCTTTATTGCAATCAATATCTTACA
CTTTATATCCCACATGGTTCAGATGAAAC	GTTGCAAGAGCTTTTATCCCAACCAGAGCTAATCT
CTTTATATCCCACATGGTTCAGATGAAAC	TGAATGCTTGAGATATTTAGTTTATAACCGAACAAGA
CTTTATATCCCACATGGTTCAGATGAAAC	TGTTGCGTTCAAAATCTCTACTTCTTTCTCTAAGCGT
CTTTATATCCCACATGGTTCAGATGAAAC	CCTGAGTTAGTTGAGGCGGGGAGAGGGGTCCTTCCTA
CTTTATATCCCACATGGTTCAGATGAAAC	TTAAACGAATGGAATGAGACAATGATAAAGCGATAC
CTTTATATCCCACATGGTTCAGATGAAAC	TGTGTATGCCAGAAGAAATTGTTTCGGCATTTTCTT
CTTTATATCCCACATGGTTCAGATGAAAC	TATCAGCAGTTCGTCAAGTTTAATGTTTTTAACAGA
CTTTATATCCCACATGGTTCAGATGAAAC	AATATCAAATTTATTACTCAACCAGCAAGGACAATAATAAC
CTTTATATCCCACATGGTTCAGATGAAAC	ACTGTACTGACACAACAGCGGAAATAACAAACTACAA
CTTTATATCCCACATGGTTCAGATGAAAC	CTCTTCTATGTTTTTGTCTTTGACATTAACCCCTTC
CTTTATATCCCACATGGTTCAGATGAAAC	TTTGTTTTTTGATAAGTTACTATTTTCGTTGTTAT
CTTTATATCCCACATGGTTCAGATGAAAC	TGCATCTGCAGGAATGCTTACAAGAGATATTTCAAG
CTTTATATCCCACATGGTTCAGATGAAAC	TAACTTTCCCTGAAAGTGCTGACATTTGAACCCATAC
CTTTATATCCCACATGGTTCAGATGAAAC	TTATACTGCTCTACTGCATCGTAGGCAAGTCTAAATA
CTTTATATCCCACATGGTTCAGATGAAAC	TCCCATCCTGCCCTGGCAAATTCTCTATAACATAAAC
CTTTATATCCCACATGGTTCAGATGAAAC	TCCTGCAAAAATCAATCTTCTTAAAATTACTGCTTT
CTTTATATCCCACATGGTTCAGATGAAAC	CTTGTTTTTACATCGTGAACCTTCCCCTTGAAACA
CTTTATATCCCACATGGTTCAGATGAAAC	TGGTGCAGGTGGCTCTGGTGGAGCTGCGGGCTCTGC
CTTTATATCCCACATGGTTCAGATGAAAC	TCGTCCGCCCACTCGCTTACCGTCTGCTTTGGTCT
CTTTATATCCCACATGGTTCAGATGAAAC	AACTTCATCCCATGCAAGCCCTCCAGGATGGAATCT
CTTTATATCCCACATGGTTCAGATGAAAC	TAAAAGCTATTCTGACATCTTTGGCAGTTTTTTCTGAA
CTTTATATCCCACATGGTTCAGATGAAAC	AACTTCAACTGGGCACATATTCCAGATGCAGACTTA
CTTTATATCCCACATGGTTCAGATGAAAC	AAAATTTCCAAACTGCCAAAAACCTTTATTTTTTCA
CTTTATATCCCACATGGTTCAGATGAAAC	AGACAGGCTTTGTTGGAAGTTTGACGGGGAGAGTATT
CTTTATATCCCACATGGTTCAGATGAAAC	GACCTTGATAGAAAAATCACTATTACCACAAGACCTC
CTTTATATCCCACATGGTTCAGATGAAAC	TTTGCTCCCTTTTTCGCACAAATTGGGCAACTGGTAGGTA
CTTTATATCCCACATGGTTCAGATGAAAC	TTGGCACACATATCAGATATTCACCATCTTTGATTGT
CTTTATATCCCACATGGTTCAGATGAAAC	AAGCTGGATGCTTGACTTCACAGTCACTGAACCATC
CTTTATATCCCACATGGTTCAGATGAAAC	CTGGTGGATTATCACGCTTCTGGTTGGCAATTTAGTC
CTTTATATCCCACATGGTTCAGATGAAAC	ATGAAATCCTCAGTAGGAACAAAGATGCCCCCACAC
CTTTATATCCCACATGGTTCAGATGAAAC	GATGCTGGACCTGCAAACATTGTTGAGGCTATTGG
CTTTATATCCCACATGGTTCAGATGAAAC

>NC_011296|5|4|1929305-1937222|CRT
CTTTATATCCCACATGGTTCAGATGAAAC	AGGATTTAATCTTTTCAAAAATCTGTCTAACCCACTG
CTTTATATCCCACATGGTTCAGATGAAAC	AAGTGTATCCTCATCTTTTCACAATCTGCCTTTATCA
CTTTATATCCCACATGGTTCAGATGAAAC	TTCCATCTTCTGTTTGAACCTCTTCCATCTGATAAC
TTTTATATCCCACATGGTTCAGATGAAAC	TAAGAACGGTGCTGACTTCACTTACTTCATCTGTCAC
CTTTATATCCCACATGGTTCAGATGAAAC	AGAATACAGAGTAATCAATTGCAGATTTCTCCAGA
CTTTATATCCCACATGGTTCAGATGAAAC	TTCAGATTCATCAAAGAAAATTTTTGGTGTCATTGC
CTTTATATCCCACATGGTTCAGATGAAAC	ATTGAGAAGAAAAGCAGAAAGAGAATTATTTTTAGA
CTTTATATCCCACATGGTTCAGATGAAAC	TGGATATTTTTCGCTGGCGTAGGTAATGGCAAGTGCA
CTTTATATCCCACATGGTTCAGATGAAAC	GAAAAATACTTTTGGAATTAGCAACTAAATATAACT
CTTTATATCCCACATGGTTCAGATGAAAC	TGAGCGGATATAACTTCATTGAGCTTGCGTGGGGAAG
CTTTATATCCCACATGGTTCAGATGAAAC	TGCTTCTTGCTTAGCTTTCCTTTCTAATTCTAAATCGT
CTTTATATCCCACATGGTTCAGATGAAAC	TATTCTACCCCAAAGATATTCCATTGCGAGGTCTTG
CTTTATATCCCACATGGTTCAGATGAAAC	AAAATATATTTTATAAGTTTATTCCTACCTCCAGTAAA
CTTTATATCCCACATGGTTCAGATGAAAC	TTAACCGTGCAATAAACATACTTGTGAACTATACAGT
CTTTATATCCCACATGGTTCAGATGAAAC	CATACCTTTCGTGAGGTGGTAGATGCTAAGGATTATTG
CTTTATATCCCACATGGTTCAGATGAAAC	TCGCAATCCCTCCTGCTATGGTAGTCCCTCCTCTGA
CTTTATATCCCACATGGTTCAGATGAAAC	TTTTTTAGCTCTTGTTTGCTCTGTTTTCTTGCTAAG
CTTTATATCCCACATGGTTCAGATGAAAC	ACAATATAAATAAGGCAGTTTCTCTTCAGGAAAAAA
CTTTATATCCCACATGGTTCAGATGAAAC	ACGCATTAATGTTGCTGAACTTGCAAGGGTAATTGGA
CTTTATATCCCACATGGTTCAGATGAAAC	TTGAGGATGTCCGTTGGCATGACCTGCGGCGAACATT
CTTTATATCCCACATGGTTCAGATGAAAC	GGGGATTGTGGATTACAGATATGACAGATTCAATC
CTTTATATCCCACATGGTTCAGATGAAAC	AGGGACTAAATCCTCTGGCGGGGTTGTTAAGAAAAA
CTTTATATCCCACATGGTTCAGATGAAAC	ACAATTAACAAAGAGTACCCCGCCGAACCGAAAACGT
CTTTATATCCCACATGGTTCAGATGAAAC	AGGAAGAAATAGTAAAGATACTGCAGCATACTCCCGGT
CTTTATATCCCACATGGTTCAGATGAAAC	GGTTCTAAAAACAGACAGAAAATTATAGGGCTTATA
CTTTATATCCCACATGGTTCAGATGAAAC	TTTTTATAATTTATCAGAACATTACTGCAGGGTATA
CTTTATATCCCACATGGTTCAGATGAAAC	ATTGAAGGAGTAATAAAAAGATTCTCTGCATCAGGC
CTTTATATCCCACATGGTTCAGATGAAAC	TTTACATAAGTGAATCAAGGGTAATTATTAAAACTGT
CTTTATATCCCACATGGTTCAGATGAAAC	TAGAAAGAAATCAGAAAAAGAAGCTCTATACATACTTT
CTTTATATCCCACATGGTTCAGATGAAAC	GATGAAGAAAAAATTAGACATAGGACAGCTTGACCTG
CTTTATATCCCACATGGTTCAGATGAAAC	GAGGGGAATGTGTTTAAGGGAGCAATTGAAAATACCTGC
CTTTATATCCCACATGGTTCAGATGAAAC	CTTGAGGCTGCCTGTCAGAGGCTTGGCTTGTCTATGCAAG
CTTTATATCCCACATGGTTCAGATGAAAC	TTTAATAAATAATGCTAATATTTCATTAAAAGCAAA
CTTTATATCCCACATGGTTCAGATGAAAC	GATGTTAAGAGTAAAAACTCCTATAATTAATCCTGC
CTTTATATCCCACATGGTTCAGATGAAAC	TTCTCTTTGAAGTTCCTATAGAGAGAATTAAATTAA
CTTTATATCCCACATGGTTCAGATGAAAC	GCATTATATAGAGAAATTCAGTACCACCGCCTTTGG
CTTTATATCCCACATGGTTCAGATGAAAC	GGAGTTGATGGATTTATATAATTATCAGGACTCGA
CTTTATATCCCACATGGTTCAGATGAAAC	AGCATGTATTTGCAAGAAGTGAACAAGAGCTTGAAC
CTTTATATCCCACATGGTTCAGATGAAAC	GAATTTGAAGTTGAAATTTCTAATGATGATTTCTTTA
CTTTATATCCCACATGGTTCAGATGAAAC	GGCAACCACTGCTGTAAAAGACAAAAAAGTAATCTCTG
CTTTATATCCCACATGGTTCAGATGAAAC	TACTGCTTCTATTGTTATGTAAGCAATTTCTCCAAC
CTTTATATCCCACATGGTTCAGATGAAAC	GGCAACCACTGCTGTAAAAGACAAAAAAGTAATCTCTG
CTTTATATCCCACATGGTTCAGATGAAAC	TACTGCTTCTATTGTTATGTAAGCAATTTCTCCAAC
CTTTATATCCCACATGGTTCAGATGAAAC	ATACTTGTTTTACAGAACACTAAAAAACACAACCGAA
CTTTATATCCCACATGGTTCAGATGAAAC	AACATGTCAGTTTTCTCATTGGCTTGAGTATCTTCTA
CTTTATATCCCACATGGTTCAGATGAAAC	AGATGTGCTGATGAGCGAGAAAGAGTTTTCAGAGAAGA
CTTTATATCCCACATGGTTCAGATGAAAC	GAAGCTAAGAAGGTTGAAGAAAAACCTGCTCAGAAGA
CTTTATATCCCACATGGTTCAGATGAAAC	TGTAAAGTAAACTACGTAACGTAGTTTACTTAAAAC
CTTTATATCCCACATGGTTCAGATGAAAC	GTTGTTGCCTTGCCTTCGTGCTTTTCAATTTGCACTT
CTTTATATCCCACATGGTTCAGATGAAAC	CAACTGTAACTGTTAAAGATGGTGAAACCACTGCTATTGT
CTTTATATCCCACATGGTTCAGATGAAAC	TCTTTTTTAGAATGAATTCTATAATTCATCATTATATT
CTTTATATCCCACATGGTTCAGATGAAAC	TTAACATCTCCCTTGTCAATCGCAGATACAGGCAA
CTTTATATCCCACATGGTTCAGATGAAAC	ATGGAAATTTATATGTAATTTTGAAAGTAGTTGCT
CTTTATATCCCACATGGTTCAGATGAAAC	CGTTGATTGCATGTTCTTAAGCACTATCTGCATTG
CTTTATATCCCACATGGTTCAGATGAAAC	ATCTATCCCTTTTTCCGCACAGATGCGGGTTCTTG
CTTTATATCCCACATGGTTCAGATGAAAC	ATGCCATAAGGGCTGTGGCAATAGTAGATGCACCAAT
CTTTATATCCCACATGGTTCAGATGAAAC	TTATACTTATTTTTGGGTTCTTGAAAAACAATCAAG
CTTTATATCCCACATGGTTCAGATGAAAC	ATATTTGCCAGAAAAGTTAAAGCAATACCTTATCTCA
CTTTATATCCCACATGGTTCAGATGAAAC	TATTACTCTCAACCCAATCACGAATTTGTTCTGTTGT
CTTTATATCCCACATGGTTCAGATGAAAC	TGCTTGAAGAACTGAAAGAACCGGAACCATACTGCA
CTTTATATCCCACATGGTTCAGATGAAAC	TGAACCCGTAATTATTCAAGATGCCGCAATATTCTTT
CTTTATATCCCACATGGTTCAGATGAAAC	TGCTTGTTGACCATAACAGAAACTTTTTAGCTCCACA
CTTTATATCCCACATGGTTCAGATGAAAC	GAGGGTGAGGACATTTGTATTATTTGATAGAATAAGT
CTTTATATCCCACATGGTTCAGATGAAAC	TTTTTGCATCTATATATGCTGTTTATATAATTTTTAAA
CTTTATATCCCACATGGTTCAGATGAAAC	ATTCTCATACTCAAAAAGAAAAGCCCTTTCTGGCTCACCATCT
CTTTATATCCCACATGGTTCAGATGAAAC	AATTTTATACTTTGCAAATTCTGTTTTTTATGTTTG
CTTTATATCCCACATGGTTCAGATGAAAC	GAATTCATGAAAAAATGCCAGAAAGCTAAATCTTTGAT
CTTTATATCCCACATGGTTCAGATGAAAC	GAGTCCATACTGTGTTGGGCAGTATAAAGAGCTCCG
CTTTATATCCCACATGGTTCAGATGAAAC	GCCATTTTTTTGTTTAGATTTCAACTTCAAAGTCTTC
CTTTATATCCCACATGGTTCAGATGAAAC	TAATATTGACAAACTTGAAAATGCAAGATGTATGATGC
CTTTATATCCCACATGGTTCAGATGAAAC	TATGATGCTGGACCTGATAAAACATTTAGAAAGCA
CTTTATATCCCACATGGTTCAGATGAAAC	GTTCAACAAACTCTTTGTGTTTGATTTTATTGACAA
CTTTATATCCCACATGGTTCAGATGAAAC	GAGACCAGATACAAGAGCATTAGGAATAGCATTAAGA
CTTTATATCCCACATGGTTCAGATGAAAC	GAAAACCACGTTTTGACAATAGAAGGTCTTACAAAA
CTTTATATCCCACATGGTTCAGATGAAAC	AAATCATCATAACCTTCTGAAGCACTTCTGGAACTGT
CTTTATATCCCACATGGTTCAGATGAAAC	AAGTTTCTTAACTTAGTATAAAAATTATCACAAATAAATTC
CTTTATATCCCACATGGTTCAGATGAAAC	CCGTTGGTAGTGGAGACAGGCTTTGTTGGAAGTTTGA
CTTTATATCCCACATGGTTCAGATGAAAC	ATCACATATGCAAAAAGATACGCATTGTCTTTAGCTCT
CTTTATATCCCACATGGTTCAGATGAAAC	GATGCAAAAGGATGTTACAGAAAATATGTTAAAAAA
CTTTATATCCCACATGGTTCAGATGAAAC	CAACGGGACAGAATGTTACTGTTGATGAAGTTGAGAT
CTTTATATCCCACATGGTTCAGATGAAAC	ATTTCAAGTTCTAAATCCTTAAAATACCTTGTATCTAT
CTTTATATCCCACATGGTTCAGATGAAAC	ACAATAAAAGATCCAAGTTGCTGTTGCGTTAAAACA
CTTTATATCCCACATGGTTCAGATGAAAC	ATAGTCTTTGCCAAAAAGTGTGGCTTTACCAATAT
CTTTATATCCCACATGGTTCAGATGAAAC	GTTATAAAGCATATTGTTATGTCTCTGAACTTCTTT
CTTTATATCCCACATGGTTCAGATGAAAC	TCACATATGCAAAAAGATACGCATTGTCTTTAGCTCT
CTTTATATCCCACATGGTTCAGATGAAAC	AGTGAACTTTGTTAGACAAATCTAACTTAGTGAGTGA
CTTTATATCCCACATGGTTCAGATGAAAC	GTAGACCCATCGCCACATATGTCTCCAATTCAACAATA
CTTTATATCCCACATGGTTCAGATGAAAC	TGAAATTCCTAAAGACAAAATCATCTATAACAAAGA
CTTTATATCCCACATGGTTCAGATGAAAC	GTATGTATCGGCTTTATTGCAATCAATATCTTACA
CTTTATATCCCACATGGTTCAGATGAAAC	GTTGCAAGAGCTTTTATCCCAACCAGAGCTAATCT
CTTTATATCCCACATGGTTCAGATGAAAC	TGAATGCTTGAGATATTTAGTTTATAACCGAACAAGA
CTTTATATCCCACATGGTTCAGATGAAAC	TGTTGCGTTCAAAATCTCTACTTCTTTCTCTAAGCGT
CTTTATATCCCACATGGTTCAGATGAAAC	CCTGAGTTAGTTGAGGCGGGGAGAGGGGTCCTTCCTA
CTTTATATCCCACATGGTTCAGATGAAAC	TTAAACGAATGGAATGAGACAATGATAAAGCGATAC
CTTTATATCCCACATGGTTCAGATGAAAC	TGTGTATGCCAGAAGAAATTGTTTCGGCATTTTCTT
CTTTATATCCCACATGGTTCAGATGAAAC	TATCAGCAGTTCGTCAAGTTTAATGTTTTTAACAGA
CTTTATATCCCACATGGTTCAGATGAAAC	AATATCAAATTTATTACTCAACCAGCAAGGACAATAATAAC
CTTTATATCCCACATGGTTCAGATGAAAC	ACTGTACTGACACAACAGCGGAAATAACAAACTACAA
CTTTATATCCCACATGGTTCAGATGAAAC	CTCTTCTATGTTTTTGTCTTTGACATTAACCCCTTC
CTTTATATCCCACATGGTTCAGATGAAAC	TTTGTTTTTTGATAAGTTACTATTTTCGTTGTTAT
CTTTATATCCCACATGGTTCAGATGAAAC	TGCATCTGCAGGAATGCTTACAAGAGATATTTCAAG
CTTTATATCCCACATGGTTCAGATGAAAC	TAACTTTCCCTGAAAGTGCTGACATTTGAACCCATAC
CTTTATATCCCACATGGTTCAGATGAAAC	TTATACTGCTCTACTGCATCGTAGGCAAGTCTAAATA
CTTTATATCCCACATGGTTCAGATGAAAC	TCCCATCCTGCCCTGGCAAATTCTCTATAACATAAAC
CTTTATATCCCACATGGTTCAGATGAAAC	TCCTGCAAAAATCAATCTTCTTAAAATTACTGCTTT
CTTTATATCCCACATGGTTCAGATGAAAC	CTTGTTTTTACATCGTGAACCTTCCCCTTGAAACA
CTTTATATCCCACATGGTTCAGATGAAAC	TGGTGCAGGTGGCTCTGGTGGAGCTGCGGGCTCTGC
CTTTATATCCCACATGGTTCAGATGAAAC	TCGTCCGCCCACTCGCTTACCGTCTGCTTTGGTCT
CTTTATATCCCACATGGTTCAGATGAAAC	AACTTCATCCCATGCAAGCCCTCCAGGATGGAATCT
CTTTATATCCCACATGGTTCAGATGAAAC	TAAAAGCTATTCTGACATCTTTGGCAGTTTTTTCTGAA
CTTTATATCCCACATGGTTCAGATGAAAC	AACTTCAACTGGGCACATATTCCAGATGCAGACTTA
CTTTATATCCCACATGGTTCAGATGAAAC	AAAATTTCCAAACTGCCAAAAACCTTTATTTTTTCA
CTTTATATCCCACATGGTTCAGATGAAAC	AGACAGGCTTTGTTGGAAGTTTGACGGGGAGAGTATT
CTTTATATCCCACATGGTTCAGATGAAAC	GACCTTGATAGAAAAATCACTATTACCACAAGACCTC
CTTTATATCCCACATGGTTCAGATGAAAC	TTTGCTCCCTTTTTCGCACAAATTGGGCAACTGGTAGGTA
CTTTATATCCCACATGGTTCAGATGAAAC	TTGGCACACATATCAGATATTCACCATCTTTGATTGT
CTTTATATCCCACATGGTTCAGATGAAAC	AAGCTGGATGCTTGACTTCACAGTCACTGAACCATC
CTTTATATCCCACATGGTTCAGATGAAAC	CTGGTGGATTATCACGCTTCTGGTTGGCAATTTAGTC
CTTTATATCCCACATGGTTCAGATGAAAC	ATGAAATCCTCAGTAGGAACAAAGATGCCCCCACAC
CTTTATATCCCACATGGTTCAGATGAAAC	GATGCTGGACCTGCAAACATTGTTGAGGCTATTGG
CTTTATATCCCACATGGTTCAGATGAAAC

>NC_011296|5|5|1933511-1937222|PILER-CR
	AGGATTTAATCTTTTCAAAAATCTGTCTAACCCACTG
CTTTATATCCCACATGGTTCAGATGAAAC	AAGTGTATCCTCATCTTTTCACAATCTGCCTTTATCA
CTTTATATCCCACATGGTTCAGATGAAAC	TTCCATCTTCTGTTTGAACCTCTTCCATCTGATAAC
TTTTATATCCCACATGGTTCAGATGAAAC	TAAGAACGGTGCTGACTTCACTTACTTCATCTGTCAC
CTTTATATCCCACATGGTTCAGATGAAAC	AGAATACAGAGTAATCAATTGCAGATTTCTCCAGA
CTTTATATCCCACATGGTTCAGATGAAAC	TTCAGATTCATCAAAGAAAATTTTTGGTGTCATTGC
CTTTATATCCCACATGGTTCAGATGAAAC	ATTGAGAAGAAAAGCAGAAAGAGAATTATTTTTAGA
CTTTATATCCCACATGGTTCAGATGAAAC	TGGATATTTTTCGCTGGCGTAGGTAATGGCAAGTGCA
CTTTATATCCCACATGGTTCAGATGAAAC	GAAAAATACTTTTGGAATTAGCAACTAAATATAACT
CTTTATATCCCACATGGTTCAGATGAAAC	TGAGCGGATATAACTTCATTGAGCTTGCGTGGGGAAG
CTTTATATCCCACATGGTTCAGATGAAAC	TGCTTCTTGCTTAGCTTTCCTTTCTAATTCTAAATCGT
CTTTATATCCCACATGGTTCAGATGAAAC	TATTCTACCCCAAAGATATTCCATTGCGAGGTCTTG
CTTTATATCCCACATGGTTCAGATGAAAC	AAAATATATTTTATAAGTTTATTCCTACCTCCAGTAAA
CTTTATATCCCACATGGTTCAGATGAAAC	TTAACCGTGCAATAAACATACTTGTGAACTATACAGT
CTTTATATCCCACATGGTTCAGATGAAAC	CATACCTTTCGTGAGGTGGTAGATGCTAAGGATTATTG
CTTTATATCCCACATGGTTCAGATGAAAC	TCGCAATCCCTCCTGCTATGGTAGTCCCTCCTCTGA
CTTTATATCCCACATGGTTCAGATGAAAC	TTTTTTAGCTCTTGTTTGCTCTGTTTTCTTGCTAAG
CTTTATATCCCACATGGTTCAGATGAAAC	ACAATATAAATAAGGCAGTTTCTCTTCAGGAAAAAA
CTTTATATCCCACATGGTTCAGATGAAAC	ACGCATTAATGTTGCTGAACTTGCAAGGGTAATTGGA
CTTTATATCCCACATGGTTCAGATGAAAC	TTGAGGATGTCCGTTGGCATGACCTGCGGCGAACATT
CTTTATATCCCACATGGTTCAGATGAAAC	GGGGATTGTGGATTACAGATATGACAGATTCAATC
CTTTATATCCCACATGGTTCAGATGAAAC	AGGGACTAAATCCTCTGGCGGGGTTGTTAAGAAAAA
CTTTATATCCCACATGGTTCAGATGAAAC	ACAATTAACAAAGAGTACCCCGCCGAACCGAAAACGT
CTTTATATCCCACATGGTTCAGATGAAAC	AGGAAGAAATAGTAAAGATACTGCAGCATACTCCCGGT
CTTTATATCCCACATGGTTCAGATGAAAC	GGTTCTAAAAACAGACAGAAAATTATAGGGCTTATA
CTTTATATCCCACATGGTTCAGATGAAAC	TTTTTATAATTTATCAGAACATTACTGCAGGGTATA
CTTTATATCCCACATGGTTCAGATGAAAC	ATTGAAGGAGTAATAAAAAGATTCTCTGCATCAGGC
CTTTATATCCCACATGGTTCAGATGAAAC	TTTACATAAGTGAATCAAGGGTAATTATTAAAACTGT
CTTTATATCCCACATGGTTCAGATGAAAC	TAGAAAGAAATCAGAAAAAGAAGCTCTATACATACTTT
CTTTATATCCCACATGGTTCAGATGAAAC	GATGAAGAAAAAATTAGACATAGGACAGCTTGACCTG
CTTTATATCCCACATGGTTCAGATGAAAC	GAGGGGAATGTGTTTAAGGGAGCAATTGAAAATACCTGC
CTTTATATCCCACATGGTTCAGATGAAAC	CTTGAGGCTGCCTGTCAGAGGCTTGGCTTGTCTATGCAAG
CTTTATATCCCACATGGTTCAGATGAAAC	TTTAATAAATAATGCTAATATTTCATTAAAAGCAAA
CTTTATATCCCACATGGTTCAGATGAAAC	GATGTTAAGAGTAAAAACTCCTATAATTAATCCTGC
CTTTATATCCCACATGGTTCAGATGAAAC	TTCTCTTTGAAGTTCCTATAGAGAGAATTAAATTAA
CTTTATATCCCACATGGTTCAGATGAAAC	GCATTATATAGAGAAATTCAGTACCACCGCCTTTGG
CTTTATATCCCACATGGTTCAGATGAAAC	GGAGTTGATGGATTTATATAATTATCAGGACTCGA
CTTTATATCCCACATGGTTCAGATGAAAC	AGCATGTATTTGCAAGAAGTGAACAAGAGCTTGAAC
CTTTATATCCCACATGGTTCAGATGAAAC	GAATTTGAAGTTGAAATTTCTAATGATGATTTCTTTA
CTTTATATCCCACATGGTTCAGATGAAAC	GGCAACCACTGCTGTAAAAGACAAAAAAGTAATCTCTG
CTTTATATCCCACATGGTTCAGATGAAAC	TACTGCTTCTATTGTTATGTAAGCAATTTCTCCAAC
CTTTATATCCCACATGGTTCAGATGAAAC	GGCAACCACTGCTGTAAAAGACAAAAAAGTAATCTCTG
CTTTATATCCCACATGGTTCAGATGAAAC	TACTGCTTCTATTGTTATGTAAGCAATTTCTCCAAC
CTTTATATCCCACATGGTTCAGATGAAAC	ATACTTGTTTTACAGAACACTAAAAAACACAACCGAA
CTTTATATCCCACATGGTTCAGATGAAAC	AACATGTCAGTTTTCTCATTGGCTTGAGTATCTTCTA
CTTTATATCCCACATGGTTCAGATGAAAC	AGATGTGCTGATGAGCGAGAAAGAGTTTTCAGAGAAGA
CTTTATATCCCACATGGTTCAGATGAAAC	GAAGCTAAGAAGGTTGAAGAAAAACCTGCTCAGAAGA
CTTTATATCCCACATGGTTCAGATGAAAC	TGTAAAGTAAACTACGTAACGTAGTTTACTTAAAAC
CTTTATATCCCACATGGTTCAGATGAAAC	GTTGTTGCCTTGCCTTCGTGCTTTTCAATTTGCACTT
CTTTATATCCCACATGGTTCAGATGAAAC	CAACTGTAACTGTTAAAGATGGTGAAACCACTGCTATTGT
CTTTATATCCCACATGGTTCAGATGAAAC	TCTTTTTTAGAATGAATTCTATAATTCATCATTATATT
CTTTATATCCCACATGGTTCAGATGAAAC	TTAACATCTCCCTTGTCAATCGCAGATACAGGCAA
CTTTATATCCCACATGGTTCAGATGAAAC	ATGGAAATTTATATGTAATTTTGAAAGTAGTTGCT
CTTTATATCCCACATGGTTCAGATGAAAC	CGTTGATTGCATGTTCTTAAGCACTATCTGCATTG
CTTTATATCCCACATGGTTCAGATGAAAC	ATCTATCCCTTTTTCCGCACAGATGCGGGTTCTTG
CTTTATATCCCACATGGTTCAGATGAAAC	ATGCCATAAGGGCTGTGGCAATAGTAGATGCACCAAT
CTTTATATCCCACATGGTTCAGATGAAAC	TTATACTTATTTTTGGGTTCTTGAAAAACAATCAAG
CTTTATATCCCACATGGTTCAGATGAAAC	ATATTTGCCAGAAAAGTTAAAGCAATACCTTATCTCA
CTTTATATCCCACATGGTTCAGATGAAAC	TATTACTCTCAACCCAATCACGAATTTGTTCTGTTGT
CTTTATATCCCACATGGTTCAGATGAAAC	TGCTTGAAGAACTGAAAGAACCGGAACCATACTGCA
CTTTATATCCCACATGGTTCAGATGAAAC	TGAACCCGTAATTATTCAAGATGCCGCAATATTCTTT
CTTTATATCCCACATGGTTCAGATGAAAC	TGCTTGTTGACCATAACAGAAACTTTTTAGCTCCACA
CTTTATATCCCACATGGTTCAGATGAAAC	GAGGGTGAGGACATTTGTATTATTTGATAGAATAAGT
CTTTATATCCCACATGGTTCAGATGAAACTTTTTGCATCTATATATGCTGTTTATATAATTTTTAAACTTTATATCCCACATGGTTCAGATGAAAC	ATTCTCATACTCAAAAAGAAAAGCCCTTTCTGGCTCACCATCT
CTTTATATCCCACATGGTTCAGATGAAAC	AATTTTATACTTTGCAAATTCTGTTTTTTATGTTTG
CTTTATATCCCACATGGTTCAGATGAAAC	GAATTCATGAAAAAATGCCAGAAAGCTAAATCTTTGAT
CTTTATATCCCACATGGTTCAGATGAAAC	GAGTCCATACTGTGTTGGGCAGTATAAAGAGCTCCG
CTTTATATCCCACATGGTTCAGATGAAAC	GCCATTTTTTTGTTTAGATTTCAACTTCAAAGTCTTC
CTTTATATCCCACATGGTTCAGATGAAAC	TAATATTGACAAACTTGAAAATGCAAGATGTATGATGC
CTTTATATCCCACATGGTTCAGATGAAAC	TATGATGCTGGACCTGATAAAACATTTAGAAAGCA
CTTTATATCCCACATGGTTCAGATGAAAC	GTTCAACAAACTCTTTGTGTTTGATTTTATTGACAA
CTTTATATCCCACATGGTTCAGATGAAAC	GAGACCAGATACAAGAGCATTAGGAATAGCATTAAGA
CTTTATATCCCACATGGTTCAGATGAAAC	GAAAACCACGTTTTGACAATAGAAGGTCTTACAAAA
CTTTATATCCCACATGGTTCAGATGAAAC	AAATCATCATAACCTTCTGAAGCACTTCTGGAACTGT
CTTTATATCCCACATGGTTCAGATGAAAC	AAGTTTCTTAACTTAGTATAAAAATTATCACAAATAAATTC
CTTTATATCCCACATGGTTCAGATGAAAC	CCGTTGGTAGTGGAGACAGGCTTTGTTGGAAGTTTGA
CTTTATATCCCACATGGTTCAGATGAAAC	ATCACATATGCAAAAAGATACGCATTGTCTTTAGCTCT
CTTTATATCCCACATGGTTCAGATGAAAC	GATGCAAAAGGATGTTACAGAAAATATGTTAAAAAA
CTTTATATCCCACATGGTTCAGATGAAAC	CAACGGGACAGAATGTTACTGTTGATGAAGTTGAGAT
CTTTATATCCCACATGGTTCAGATGAAAC	ATTTCAAGTTCTAAATCCTTAAAATACCTTGTATCTAT
CTTTATATCCCACATGGTTCAGATGAAAC	ACAATAAAAGATCCAAGTTGCTGTTGCGTTAAAACA
CTTTATATCCCACATGGTTCAGATGAAAC	ATAGTCTTTGCCAAAAAGTGTGGCTTTACCAATAT
CTTTATATCCCACATGGTTCAGATGAAAC	GTTATAAAGCATATTGTTATGTCTCTGAACTTCTTT
CTTTATATCCCACATGGTTCAGATGAAAC	TCACATATGCAAAAAGATACGCATTGTCTTTAGCTCT
CTTTATATCCCACATGGTTCAGATGAAAC	AGTGAACTTTGTTAGACAAATCTAACTTAGTGAGTGA
CTTTATATCCCACATGGTTCAGATGAAAC	GTAGACCCATCGCCACATATGTCTCCAATTCAACAATA
CTTTATATCCCACATGGTTCAGATGAAAC	TGAAATTCCTAAAGACAAAATCATCTATAACAAAGA
CTTTATATCCCACATGGTTCAGATGAAAC	GTATGTATCGGCTTTATTGCAATCAATATCTTACA
CTTTATATCCCACATGGTTCAGATGAAAC	GTTGCAAGAGCTTTTATCCCAACCAGAGCTAATCT
CTTTATATCCCACATGGTTCAGATGAAAC	TGAATGCTTGAGATATTTAGTTTATAACCGAACAAGA
CTTTATATCCCACATGGTTCAGATGAAAC	TGTTGCGTTCAAAATCTCTACTTCTTTCTCTAAGCGT
CTTTATATCCCACATGGTTCAGATGAAAC	CCTGAGTTAGTTGAGGCGGGGAGAGGGGTCCTTCCTA
CTTTATATCCCACATGGTTCAGATGAAAC	TTAAACGAATGGAATGAGACAATGATAAAGCGATAC
CTTTATATCCCACATGGTTCAGATGAAAC	TGTGTATGCCAGAAGAAATTGTTTCGGCATTTTCTT
CTTTATATCCCACATGGTTCAGATGAAAC	TATCAGCAGTTCGTCAAGTTTAATGTTTTTAACAGA
CTTTATATCCCACATGGTTCAGATGAAAC	AATATCAAATTTATTACTCAACCAGCAAGGACAATAATAAC
CTTTATATCCCACATGGTTCAGATGAAAC	ACTGTACTGACACAACAGCGGAAATAACAAACTACAA
CTTTATATCCCACATGGTTCAGATGAAAC	CTCTTCTATGTTTTTGTCTTTGACATTAACCCCTTC
CTTTATATCCCACATGGTTCAGATGAAAC	TTTGTTTTTTGATAAGTTACTATTTTCGTTGTTAT
CTTTATATCCCACATGGTTCAGATGAAAC	TGCATCTGCAGGAATGCTTACAAGAGATATTTCAAG
CTTTATATCCCACATGGTTCAGATGAAAC	TAACTTTCCCTGAAAGTGCTGACATTTGAACCCATAC
CTTTATATCCCACATGGTTCAGATGAAAC	TTATACTGCTCTACTGCATCGTAGGCAAGTCTAAATA
CTTTATATCCCACATGGTTCAGATGAAAC	TCCCATCCTGCCCTGGCAAATTCTCTATAACATAAAC
CTTTATATCCCACATGGTTCAGATGAAAC	TCCTGCAAAAATCAATCTTCTTAAAATTACTGCTTT
CTTTATATCCCACATGGTTCAGATGAAAC	CTTGTTTTTACATCGTGAACCTTCCCCTTGAAACA
CTTTATATCCCACATGGTTCAGATGAAAC	TGGTGCAGGTGGCTCTGGTGGAGCTGCGGGCTCTGC
CTTTATATCCCACATGGTTCAGATGAAAC	TCGTCCGCCCACTCGCTTACCGTCTGCTTTGGTCT
CTTTATATCCCACATGGTTCAGATGAAAC	AACTTCATCCCATGCAAGCCCTCCAGGATGGAATCT
CTTTATATCCCACATGGTTCAGATGAAAC	TAAAAGCTATTCTGACATCTTTGGCAGTTTTTTCTGAA
CTTTATATCCCACATGGTTCAGATGAAAC	AACTTCAACTGGGCACATATTCCAGATGCAGACTTA
CTTTATATCCCACATGGTTCAGATGAAAC	AAAATTTCCAAACTGCCAAAAACCTTTATTTTTTCA
CTTTATATCCCACATGGTTCAGATGAAAC	AGACAGGCTTTGTTGGAAGTTTGACGGGGAGAGTATT
CTTTATATCCCACATGGTTCAGATGAAAC	GACCTTGATAGAAAAATCACTATTACCACAAGACCTC
CTTTATATCCCACATGGTTCAGATGAAAC	TTTGCTCCCTTTTTCGCACAAATTGGGCAACTGGTAGGTA
CTTTATATCCCACATGGTTCAGATGAAAC	TTGGCACACATATCAGATATTCACCATCTTTGATTGT
CTTTATATCCCACATGGTTCAGATGAAAC	AAGCTGGATGCTTGACTTCACAGTCACTGAACCATC
CTTTATATCCCACATGGTTCAGATGAAAC	CTGGTGGATTATCACGCTTCTGGTTGGCAATTTAGTC
CTTTATATCCCACATGGTTCAGATGAAAC	ATGAAATCCTCAGTAGGAACAAAGATGCCCCCACAC
CTTTATATCCCACATGGTTCAGATGAAAC	GATGCTGGACCTGCAAACATTGTTGAGGCTATTGG
CTTTATATCCCACATGGTTCAGATGAAAC

Protein	Signature genes	Signature genes Name	Protein_function
NC_011296.1\|WP_012545385.1\|1926860_1929077_+\|hypothetical-protein	unknown	unknown	unknown
NC_011296.1\|WP_012546783.1\|1926407_1926839_+\|hypothetical-protein	unknown	unknown	unknown
NC_011296.1\|WP_012544994.1\|1940908_1943095_-\|CRISPR-associated-helicase/endonuclease-Cas3	cas3	cd09639_cas3_CAS-I	gnl\|CDD\|224124
NC_011296.1\|WP_012546411.1\|1937714_1937981_-\|CRISPR-associated-endonuclease-Cas2	cas2	cd09725_cas2_CAS-I:CAS-II:CAS-III:CAS-V	gnl\|CDD\|187856
NC_011296.1\|WP_012546881.1\|1917452_1919171_+\|type-IV-A-pilus-assembly-ATPase-PilB	unknown	unknown	gnl\|CDD\|274186
NC_011296.1\|WP_164924876.1\|1925199_1925430_+\|hypothetical-protein	unknown	unknown	unknown
NC_011296.1\|WP_012546576.1\|1939622_1940834_-\|ATP-binding-protein	unknown	unknown	gnl\|CDD\|379306
NC_011296.1\|WP_012545291.1\|1938113_1939091_-\|type-I-B-CRISPR-associated-endonuclease-Cas1	cas1	cd09722_cas1_CAS-I-B	gnl\|CDD\|274695
NC_011296.1\|WP_012545101.1\|1922092_1924003_+\|adenylate/guanylate-cyclase-domain-containing-protein	unknown	unknown	gnl\|CDD\|215016
NC_011296.1\|WP_012545959.1\|1947479_1948820_+\|Trk-system-potassium-transporter-TrkA	unknown	unknown	gnl\|CDD\|236541
NC_011296.1\|WP_012545751.1\|1939094_1939616_-\|CRISPR-associated-protein-Cas4	cas4	pfam01930_cas4_CAS-I	gnl\|CDD\|366863
NC_011296.1\|WP_012546885.1\|1943097_1943817_-\|CRISPR-associated-protein-Cas5	cas5	cd09658_cas5_CAS-I-B	gnl\|CDD\|273860
NC_011296.1\|WP_028842903.1\|1924565_1924796_-\|hypothetical-protein	unknown	unknown	unknown
NC_011296.1\|WP_012546308.1\|1921328_1922093_+\|3',5'-cyclic-nucleotide-phosphodiesterase	unknown	unknown	gnl\|CDD\|293821
NC_011296.1\|WP_012545393.1\|1925560_1926259_+\|hypothetical-protein	unknown	unknown	unknown
NC_011296.1\|WP_012546265.1\|1946536_1947325_-\|CRISPR-associated-endoribonuclease-Cas6	cas6	cd09652_cas6_CAS-I:CAS-III	gnl\|CDD\|187783
NC_011296.1\|WP_012545957.1\|1919170_1920247_+\|HD-domain-containing-protein	unknown	unknown	gnl\|CDD\|225971
NC_011296.1\|WP_012546150.1\|1944715_1946380_-\|type-I-B-CRISPR-associated-protein-Cas8b1/Cst1	cas8b2	cd09665_cas8b2_CAS-I-B	gnl\|CDD\|187796
NC_011296.1\|WP_012544921.1\|1943813_1944713_-\|type-I-B-CRISPR-associated-protein-Cas7/Cst2/DevR	cas7	cd09687_cas7_CAS-I-B	gnl\|CDD\|274215
NC_011296.1\|WP_012545054.1\|1920246_1921332_+\|HD-domain-containing-protein	unknown	unknown	gnl\|CDD\|225116

Protein	Function_ID	Function_description	E-value
NC_011296.1\|WP_012546881.1\|1917452_1919171_+\|type-IV-A-pilus-assembly-ATPase-PilB	gnl\|CDD\|274186	TIGR02538, Type_IV_pilus_assembly_protein_PilF, type IV-A pilus assembly ATPase PilB. This model describes a protein of type IV pilus biogenesis designated PilB in Pseudomonas aeruginosa but PilF in Neisseria gonorrhoeae; the more common usage, reflected here, is PilB. This protein is an ATPase involved in protein export for pilin assembly and is closely related to GspE (TIGR02533) of type II secretion, also called the main terminal branch of the general secretion pathway. Note that type IV pilus systems are often divided into type IV-A and IV-B, with the latter group including bundle-forming pilus, mannose-sensitive hemagglutinin, etc. Members of this family are found in type IV-A systems. [Cell envelope, Surface structures, Protein fate, Protein and peptide secretion and trafficking].	0
NC_011296.1\|WP_012544994.1\|1940908_1943095_-\|CRISPR-associated-helicase/endonuclease-Cas3	gnl\|CDD\|224124	COG1203, COG1203, CRISPR-associated helicase Cas3 [Defense mechanisms].	9.03094e-65
NC_011296.1\|WP_012545054.1\|1920246_1921332_+\|HD-domain-containing-protein	gnl\|CDD\|225116	COG2206, COG2206, c-di-GMP phosphodiesterase class II (HD-GYP domain) [Signal transduction mechanisms].	7.53011e-64
NC_011296.1\|WP_012546265.1\|1946536_1947325_-\|CRISPR-associated-endoribonuclease-Cas6	gnl\|CDD\|187783	cd09652, Cas6-I-III, CRISPR/Cas system-associated RAMP superfamily protein Cas6. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas6 is an endoribonuclease that generates crRNAs, predicted subunit of Cascade complex; RAMP superfamily protein; Possesses double RRM/ferredoxin fold.	1.71536e-34
NC_011296.1\|WP_012546576.1\|1939622_1940834_-\|ATP-binding-protein	gnl\|CDD\|379306	pfam13635, DUF4143, Domain of unknown function (DUF4143). This domain is almost always found C-terminal to an ATPase core family.	7.19404e-53
NC_011296.1\|WP_012545291.1\|1938113_1939091_-\|type-I-B-CRISPR-associated-endonuclease-Cas1	gnl\|CDD\|274695	TIGR03641, cas1_HMARI, CRISPR-associated endonuclease Cas1, subtype I-B/HMARI/TNEAP. The CRISPR-associated protein Cas1 is virtually universal to CRISPR systems. CRISPR, an acronym for Clustered Regularly Interspaced Short Palindromic Repeats, is prokaryotic immunity system for foreign DNA, mostly from phage. CRISPR systems belong to different subtypes, distinguished by both nature of the repeats, the makeup of the cohort of associated Cas proteins, and by molecular phylogeny within the more universal Cas proteins such as this one. This model is of type EXCEPTION and provides more specific information than the EQUIVALOG model TIGR00287. It describes Cas1 subgroup that includes Cas1 proteins of the related HMARI and TNEAP subtypes of CRISPR/Cas system.	1.293e-173
NC_011296.1\|WP_012546885.1\|1943097_1943817_-\|CRISPR-associated-protein-Cas5	gnl\|CDD\|273860	TIGR01895, conserved_hypothetical_protein, CRISPR-associated protein Cas5, subtype I-B/TNEAP. CRISPR is a term for Clustered Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR associated) proteins. This family is represented by TM1800 from Thermotoga maritima. It is related to TIGR01868 (CRISPR-associated protein, CT1976 family).	1.67217e-13
NC_011296.1\|WP_012545101.1\|1922092_1924003_+\|adenylate/guanylate-cyclase-domain-containing-protein	gnl\|CDD\|215016	smart01080, CHASE2, CHASE2 is an extracellular sensory domain, which is present in various classes of transmembrane receptors that are parts of signal transduction pathways in bacteria. Specifically, CHASE2 domains are found in histidine kinases, adenylate cyclases, serine/threonine kinases and predicted diguanylate cyclases/phosphodiesterases. Environmental factors that are recognised by CHASE2 domains are not known at this time.	2.32325e-81
NC_011296.1\|WP_012545959.1\|1947479_1948820_+\|Trk-system-potassium-transporter-TrkA	gnl\|CDD\|236541	PRK09496, trkA, Trk system potassium transporter TrkA.	0
NC_011296.1\|WP_012546150.1\|1944715_1946380_-\|type-I-B-CRISPR-associated-protein-Cas8b1/Cst1	gnl\|CDD\|187796	cd09665, Cas8a1_I-A, CRISPR/Cas system-associated protein Cas8a1. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Large proteins, some contain Zn-finger domain; signature gene for I-A subtype; also known as CXXC_CXXC family.	1.71884e-18
NC_011296.1\|WP_012546308.1\|1921328_1922093_+\|3',5'-cyclic-nucleotide-phosphodiesterase	gnl\|CDD\|293821	cd07735, class_II_PDE_MBL-fold, class II cyclic nucleotide phosphodiesterases Saccharomyces cerevisiae PDE1, Dictyostelium discoideum PDE1 and PDE7, and related proteins; MBL-fold metallo-hydrolase domain. Cyclic nucleotide phosphodiesterases (PDEs) decompose the second messengers cyclic adenosine and guanosine 3',5'-monophosphate (cAMP and cGMP, respectively). Saccharomyces cerevisiae PDE1 and Dictyostelium discoideum PDE1 and PDE7, have dual cAMP/cGMP specificity. Members of this subgroup belong to the MBL-fold metallo-hydrolase superfamily which is comprised mainly of hydrolytic enzymes which carry out a variety of biological functions.	6.2072e-74
NC_011296.1\|WP_012545751.1\|1939094_1939616_-\|CRISPR-associated-protein-Cas4	gnl\|CDD\|366863	pfam01930, Cas_Cas4, Domain of unknown function DUF83. This domain has no known function. The domain contains three conserved cysteines at its C-terminus.	9.17771e-61
NC_011296.1\|WP_012545957.1\|1919170_1920247_+\|HD-domain-containing-protein	gnl\|CDD\|225971	COG3437, COG3437, Response regulator containing a CheY-like receiver domain and an HD-GYP domain [Transcription / Signal transduction mechanisms].	9.236e-63
NC_011296.1\|WP_012544921.1\|1943813_1944713_-\|type-I-B-CRISPR-associated-protein-Cas7/Cst2/DevR	gnl\|CDD\|274215	TIGR02585, conserved_protein, CRISPR-associated protein Cas7/Cst2/DevR, subtype I-B/TNEAP. CRISPR is a term for Clustered Regularly Interspaced Short Palidromic Repeats. A number of protein families appear only in association with these repeats and are designated Cas (CRISPR associated) proteins. This clade is a member of the DevR family (TIGR01875) and includes the DevR protein of Myxococcus xanthus, a protein whose expression appears to be regulated through a number of means, including both location and autorepression; DevR mutants are incapable of fruiting body development.	1.33147e-47
NC_011296.1\|WP_012546411.1\|1937714_1937981_-\|CRISPR-associated-endonuclease-Cas2	gnl\|CDD\|187856	cd09725, Cas2_I_II_III, CRISPR/Cas system-associated protein Cas2. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas2 is present in majority of CRISPR/Cas systems along with Cas1; RNAse specific to U-rich regions; Possesses an RRM/ferredoxin fold.	1.26221e-27

>NC_011296.1|WP_012545385.1|1926860_1929077_+|hypothetical-protein
MRTYFYFLSIFLILIPQLLTAQSQTPYFEKSLDEYNPPLVSDMVPRELLNFKPVSFKFYGGTITELKATTKGGLSRKSDEQEYGKKLHFEWQIKGKLVTLDYYIVSWENAQKYFGGKKVHPNTYTYLKIIDKKIRNVCSGGNCPHLFVESNLPDEHNKCDFYANPDKISPIPFKSNYYIYKQCAMAGGQKFYNIYVGLWSYANVFIEVTAYDIDTLKKLGESAVAKLMGKSVPVEQPVEKPKEVQKEQLKQESPEVRVIAMPSAAGDDLWSIAYLPATNKLPAKIIAETKPNTPVTFHIVKSPKDAYLVIGDKKGVTIETKSDSKGIAEALFYYNGGKVTQPKKYEIKVSTGEERDIATVNVGLGLAFDKIKAVQGAYGDRHPFTLSLVSKYFPKLNLGLYFSSASRKVWNGQTVGVRLKPQWVNKTPDLPADMVFNGITKITPVMASSGGNNVLTVLSYSSGEETVYNITKYAYPAVKMMSDGIHNYRIVGELVLTDEEGRDLGGIDESLVQSDALAVVSKDTPEHFMVSLVCALEAQNADQFVMLDYIKRFPVYGKYADEFLNVTGILCKLGKEDYEGLFYDLNNYLGGKWLDHLTSKEVFPKLTPRQQKAAKWAKAAFDATQKIKTKREYDEWEVKDPARRSAQSLNPDHDAKKLEYNRELIAPALIDFKEAEEALQKMEEKQPKNKPIEANFNNENLKKIDEQKTQGQGSENTEGNVFEKAVNELKDTFKKIFK
>NC_011296.1|WP_012546783.1|1926407_1926839_+|hypothetical-protein
MLIDEIKKLLQNYDGSLEEKKDTYKFETVIAERKSFLSRKKLMYIIKFKIDDIYRKFIFSEMLKETGFGLSSSAGDDEMSSGFTFKKYKTKQGFGTPIEETIEEQSNLFGQKYNYKFDFKVIREKIKQISQQNGYEFEYKIWF
>NC_011296.1|WP_012545393.1|1925560_1926259_+|hypothetical-protein
MTKQLSVLTLTLTVFIFLWVAVFDAHAQGNQQQSQAFQMKDFSKSPSQKPSTSVSDMIKCIYDKCPANLKKNTTSSQNPNLPQQKTNPQAQTTPENKSVTIQNTPTKPDVIKTKTDPKKMNSIFVSKPRSEEEKANSQNQPKMVSPEEMRDILTGKKPVPQSSNQQQPQQQKQTEKIAPNLVIQDMGGNPAQQNQNRQMTQTQNQNQNKTIQQNCVKDPKKPFASCDLGGKK
>NC_011296.1|WP_164924876.1|1925199_1925430_+|hypothetical-protein
MFIFIFISVSFEAYAVNFKGEAIKKLCAAEPVKEGKRYICPYCAEVTEFAGESWEKFVITDVIEEIFITGKKVKYV
>NC_011296.1|WP_028842903.1|1924565_1924796_-|hypothetical-protein
MPDQVLTNTIYFILLLPFSIIAAVMVYLITYNEYMHHYTTKKEPRKIALETAIFTFVFFIVVGFFIVYVLINWIEK
>NC_011296.1|WP_012545101.1|1922092_1924003_+|adenylate/guanylate-cyclase-domain-containing-protein
MDINKLIQLLRAQKNKETIVSVFIVIIFLVLFYIKPYPFELVDMKIYDLFFHLRGQETPPKSVVIAAIDEASLEKFGRWPWSRDKIAKVIDKLSELEAAVITFDIILSEHEQNDRVLADSISKAGNVILPVVFFFNENAPEELTIISSAFPVLNTQNLKRYHPISSKNVLVCQKILAENAAGFGHINMFPDPDGTIRWEVLFIEYYGYMIPSLSLKTVSMYLGIPPEKQAIDANRGVYLGKRYIPTDPWGRFLIPYYGGNETFKHISIVDILEDKVKKEDIENKIVIVGATAVGIYDLRVTPLSSVLPGVEKHANVVAAIIDGKTLLPASSFLVSLLIFLSGIISILFYKKLKAGYSMIVLMSLLVIVFSISFVFFKNGIWLSIVYISGNLVTQFLTTITIKYAYSEKEARQIKKIFSSYVTEKIVNELIKNPSMAKLGGARREVTVLFSDIRDFTTLSEKLPPEKVVEILNEYFSTMAEIIFKWEGTLDKFMGDAIMVFWGAPLPQNDHPEKALKCAIEMISKLRYLHSKWKAENKPLLKIGIGISTGEVLVGNIGAEGKKMDYTVIGDHVNLACRLEKLNKQFDSEILISEFTYERMKETIDSEYLDSIYVEELGTILVKGKETPVKIFKVSLR
>NC_011296.1|WP_012546308.1|1921328_1922093_+|3',5'-cyclic-nucleotide-phosphodiesterase
MKIRVLGASGSDIPGHHLSSFLLNNKILFDAGGVTSSLSFTAQQKIEHIFITHAHLDHIRDIPFLADNIILSGKSKRINIYSIKEVIDDIKKHLLNYRLWPDFTVIPDVKNSILDLKIIHEEKSILLDGYKITAYRMNHTVPAVGFLVEKEGRSFFYTGDTGPAINTWKKFLNKKLNALIIEVSLPDKMKDLATKTGHLTPRLLFEDLKLFNQKPEKIFITHIKPLYKKAIERELKKYSDYKIEILQGRESIKI
>NC_011296.1|WP_012545054.1|1920246_1921332_+|HD-domain-containing-protein
MEKEILLEHLKELLEFSKIINSSLEIEEIRKKAALAAVKLVNCEAGSLLLFDEELEELYFDVALGEKAEKVKMIKLKKGQGIAGWVAKHKEAVIINDVQKDPRFYKGADEKSGFKTKTMICLPVMIKDKVLGVIQAINKKNSLFNEYDLELLRALASQVAVAIENARLYEELKETFYSIVFALADTIEKRDPYTGGHTKRVMDYSVAIGIEMELSKKEIEKLRLAAILHDIGKIGIRDEILLKKEELSDEEFKIIQNHTIYGAEILNYVKQLKDIIPGVKHHHEEFSGSGYPDQLKGYEIPLIARIIAVADTFDAMTTDRPYRKALSVNEAMKELQNKAGTQFDPHVIDAFQKAFTKMKKL
>NC_011296.1|WP_012545957.1|1919170_1920247_+|HD-domain-containing-protein
MNKLEILLKAAGKISREKNLNNLISILSNLAKDIIEVDRCSLFLIDEQKKELYTIFAHGVKEIRIPITSGIAGYVVKTGKTYVTSDAYKSKFFNPEVDKISGYTTRNILAVPIFDSRGRIIGVYQAINKLDDFNSVDIKLMKLIAEFAAAAIETQMLYEKIKSVHKKALIKLSKAAEYKDPESPNHFLRVGLISSLLAEKLGLDEEKCELLMLASTMHDIGKIGIPDSILQKSGRLEPDEWEVMKKHPIIGYELLFDEESELLQMAAIIALEHHERWDGKGYPFGKRETEISLWARIVSVVDNFDTLTTDKGNRESWSIDAAINYMEIMKEKAFDPQIVDTFLSNIEKIIEIKEKYKD
>NC_011296.1|WP_012546881.1|1917452_1919171_+|type-IV-A-pilus-assembly-ATPase-PilB
MSTKLTSERLTIGVFLLKKGKISEKQLIDAQAVQKIEGIKIGAALIKLGYITEDELVESMSELYGYPVFKIDSYKIDPLVVKLLPEDVIRKYKVLPFLREGNIIRVLITDPANEIALEQLKFFLSGFKILFYIGKDSDFKNLINKFFGEEGAEIYSKETVHELVESAVQEPSITQPEEEQAILEVDAPLIRLVNQIIVNAISKRASDIHIEPFEDNIYIRYRIDGVLHDILTLPPKLKSALITRIKIMANMDISERRLPQDGRIKMKIGKKEVDFRVSTLPSIFGEKIVLRILEKGSLQLDLTKLGFEEESLNFFIEALSKPYGMILVTGPTGSGKTTTLYSSLMKLRKPEVNIVTVEDPVEYTLPRITQVQVQEDIGRTFAQVLRSFLRQDPDIILVGEIRDFETAEIAIKAALTGHLVLSTLHTNDAPSTITRLVNMGIEPFLIASSVILIVAQRLVRKLCESCKKEQKISKETFLKLGFPEESFDSLKIYEAQGCAECNQTGYRGRVALYEVMPIKDEIRELILTGASTNEIKKEAIKLGMLTLRHSGIRKIMAGITSIEEVLRVTVED
>NC_011296.1|WP_012546411.1|1937714_1937981_-|CRISPR-associated-endonuclease-Cas2
MPYLIVTYDIAEERVNKVRKILKKYFMWVQNSVFEGEITEGKLLKCKLELEKVIDKEVDSVYFYSLENRLNYRKTVLGIEKEITGNIL
>NC_011296.1|WP_012545291.1|1938113_1939091_-|type-I-B-CRISPR-associated-endonuclease-Cas1
MRNYYIFSNGRIRRKENTIYIENEQGDRKAIPIEDVDTIHIFGEVDLNTKLLNFICQQGKTVHFYNYYGFYSGSLMPRERNVSGHIVVKQVEHFLDPERRFYLAYSFVEGAIFHMVRNLREYKNTDEFQEKIKKELSNAVETTKISELMGCEGRARDFYYEAFNTFLKSDFSMGKREKRPPRNPINALISFANSMIYTTVLNEIYHTQLNPTVSYLHEPSERRYSLSLDIAEIFKPLLADAIIFKLINNNMIKLDDFEEDVNYCYLNESGRKKFIREFDQKLSTTIKHRKLKRNVSYRTIIRIECYKLIKHFIGDEVYAPFKAWW
>NC_011296.1|WP_012545751.1|1939094_1939616_-|CRISPR-associated-protein-Cas4
METLRQEFDFQTLRTNGIKVNYLYVCERKLWFFDRGIQMESKSDKVLMGKLLSEYSYPAEEKRELLIDNLINIDIVGDDQIREVKYSNRLAHADRIQLLYYLYYLKQIGIEKKGIINYPKMRKREEITLTPEAEREVEEALVRVREIVSMEKPPELKKKPYCTKCAYFEFCWS
>NC_011296.1|WP_012546576.1|1939622_1940834_-|ATP-binding-protein
MLFHRIISSKLSTAMRYFPAVFLTGARQVGKSTLALSMFKNYVTLDDTTVYESALADPPLFVSNLKKPVVIDEIQKLPRLLNSIKLDIDKNRINGSYLLTGSANILAFKDISDTLAGRMAIIELFPLSCKEISKKTENVIEILFNANFKDFTLPLIETDLIIEQVIKGGYPEIQKIDTVTGRYLWFSSYIRTYIERDVRDLGELRNLDKFIKMFNLLAPRSANLLNKSDIARDAQLEIKTLENYLNLLKMVYQIYILAPYSRNISKRIIKTGKLFFTDSGILSHLLGVSTKEDLMQSPYKGLIFETFVFSEILKATKYSDKPAELFFYRTHDRQEIDFVIEQGRSIIAIEVKFSKTVTRDDFKYIASLDKAVRNLKAGYVLYMGERILPFGEKFFALPVSILF
>NC_011296.1|WP_012544994.1|1940908_1943095_-|CRISPR-associated-helicase/endonuclease-Cas3
MPVFAKSNPPETIEEHNKKIFENYERIKPFLDPEKIKKYDEVIKKIIYYHDLGKLNHKFQNKLGLSKKVIIPELKDIDEIPHEWLSLAFLSREDKRYFHTLSTDTIHFADLVQYCIAFHHTRTKPFDKKALEKTICHDLEKNKGLLGINHSLNFDYDIFKDIKQKIDSQKNFKNYFELLVFLKGILHKCDYTASANIEPESHYSGNYEKDFNNWLSKKGWHLKPFQNEAKRLSDKSVVLVASTGTGKTEYSMNWINGQKAFYLLGIRTAVNEMYRRFKDIFGENVSLLHGEISNIIEDDDTEERYVERIETARKLSTPLTVATADQLVTSVFKYNGFEMTYLTASYSKIVLDEIQSFSPDSIAAIMVFLKEVHRLGSKFLIMTATLPPFIKEELKELQNVEFPEPVLLPNKRHFITVYDEPIDSERSLKMIDKNFKSGKKILIVCNTVKKAQQMYDMLKNFNPSLLHSRYILKDRKNKESRDHGIMAVNNPKHPPVIWIATQVVEASLDLDFDALFTECSPIDSLLQRFGRCWRKREYTDNKPNIHIFKAEDNRIYDKELLDRTYSLIFNNYKNKIMDERDKQDAIFTIFKDIEKTKYYEKYKRNKELLELGFKAQSKTEAEAFFRNIAFNYCVIPRLVYEENEKEIRNLIELIDNKDTEKMQRIKAKAKIKDFIIPLQIFGNFKNLTPVPDSEYCKRNNIMIMNEVTYSYEKGLQLKDTAGEGVLID
>NC_011296.1|WP_012546885.1|1943097_1943817_-|CRISPR-associated-protein-Cas5
MKAVRIKLYQNMVNYRKELSYGYVQTYPLPTPSMVKGMAHSLLNLNKYHNLKISIQGNYASVVTNMQKVYKFDRVRDDKKREFIDPRPRIYAGGQRVLNQGIMFVDEIVDMELILHISFDDEGLNDKLLEALKQKTVILGRNEDIARVDFEDTSLVDILSFSDEYRLPYNIYLAPELCKKEQLEGTCYRLPFYYEPVNSFTDKRIFRYVNAIYIAKGNKIQYSEINVDSDRYIVSFLSI
>NC_011296.1|WP_012544921.1|1943813_1944713_-|type-I-B-CRISPR-associated-protein-Cas7/Cst2/DevR
MIAQKYLHLAVIFKASNLNYGEGVGNILTLKKVTTEGKNYSYISRQALRYDVVRMLNELCGYRLTDVDRQAGVIQFAEHATIKDFPEIDFFGYMKTTTSNKIRKAVVRLTDAVSLEPFYNELEFATNKGLADRIPNNVGNDIFQAEIHRSYYCYTLTCNLEEIGVDPIYEIVLDNTERSNRVKCLLNVIKLLNRDIRGKRENLSPLFVIGGLYDVGNPFFYNRIKLSFTKDKIMLNEKLINSTLAIKTFENTVGQQSMLGYIDGEFSNIDDIDIKDKFPIEDFFTKLNEKIDNFYNGLK
>NC_011296.1|WP_012546150.1|1944715_1946380_-|type-I-B-CRISPR-associated-protein-Cas8b1/Cst1
MVNDSIKLYPSTVKHKIYMRDWYFNAGIVGFLNIITDGKELDSIPYLTIGENYIEFSDEIFEGFEEKFSKYAFLKFFNVNAYLQRLQKAQKDLTEKKTKIKPEQIRKKLEEIEKPPYKDFLKLLNIPVWEYKSAEDFIDNLEKAQSKLKNLSKNQIFEILNKTPEGKESIQIFINQKLKGVCSHENVSEYVSRIKAMKYSKKLKNNELCPSCQEKKAEYEFNNAVSNIIGFNKDNSNWIWGFKVSKLQICPLCAIIYSCAFASFAYVLKIAEGEYLNYFYFPNENTNLKTLYEIVKTFNLLIDNIEENSNLLYVMIKQIVDYITKKQINRISENINFIEIADNPILAGQGTKGYNIYNYNISPDIAMFLDLQFKNESVPKGYYVLNKNYCSIEEELLKLAISYQIDYSTLYRYFAYYLDTDNYSTKYNLNKVMNFVIKYIQWVRGESMEKSQKIINKGYLSGLSLRNELIKKGKENQINGLVYGFLNDLKIGDREKFLDKYLRIVMSHNQPNRFGKDEMLDDDYFLQFGYSFVSGLISKSGIENNTGTNDIEEE
>NC_011296.1|WP_012546265.1|1946536_1947325_-|CRISPR-associated-endoribonuclease-Cas6
MRIKVIFYAPKLPILYRNRFMSLIKDSLEKSDSAYKEKLYPDKSQEITKVVKPFCFCVTIPASRQTKKEKIIIDKDFEIEDTVFYFLDTGYVSLIVSSSDYEFMVNLYNGLLENKSFQFSDELTFMLKRIFMLNEKKIENDSVTFKTLCPALIETKDGKPILPSDNVEDFNIEFNAIHDRIFKDIRGYGLKRALEFEPLSLKKQVVKHTLKGFREKTGKPYMTLTCFEGSFRLSGDPEDLRLLYQIGIGLRTGQGFGMVEVC
>NC_011296.1|WP_012545959.1|1947479_1948820_+|Trk-system-potassium-transporter-TrkA
MRVIIVGAGEVGYQIAKFLTYEGVDVVIIDRDGSKLRRISEELDIATIEAEGSDPSAFKEAGADNADLLLAVTNSDETNMIACLLGKAMFNIKRKIARIRNPDYFFNKELLGKANLDIDPAINPELEAAEAVSRLIESPFASEIIEFEKGKIKVIGFKIPQDSPITGKKLKSIKTFLKKDFIIGIIERDENVIVPSGEDILNEGNIVYIPVRKEEVEEVAQSLGVPAKPAKKIMILGGGRIGYYIASKMENRADIKIIEKDPERCKFLSKHLGKSLVLHGDGADKQLLLEENISNMDTYIACSNNDELNIMASLLAKKLGAKKVIALVNRTDYVPLAHNLGIQSVLSPRLITAGIILRYVRKGEVLSLTAIAENKAEIIEVVVNKTSSLIGKTLKEGIFPKNSILGAIIRDDRIIIPSGEDFIKEKDKLIIFALKDSIKEVEKLLT

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NC_011296_2	2.6\|632426\|32\|NC_011296\|PILER-CR,CRISPRCasFinder,CRT	632426-632457	32	NZ_CP009417	Jeotgalibacillus malaysiensis strain malaysiensis plasmid unnamed, complete sequence	116236-116267	7	0.781
NC_011296_2	2.6\|632426\|32\|NC_011296\|PILER-CR,CRISPRCasFinder,CRT	632426-632457	32	NC_047948	Staphylococcus phage phiSA_BS2, complete genome	45509-45540	7	0.781
NC_011296_2	2.6\|632426\|32\|NC_011296\|PILER-CR,CRISPRCasFinder,CRT	632426-632457	32	MH078572	Staphylococcus phage phiSA_BS1, complete genome	363-394	7	0.781
NC_011296_2	2.6\|632426\|32\|NC_011296\|PILER-CR,CRISPRCasFinder,CRT	632426-632457	32	MN582070	Myoviridae sp. ctThM1, complete genome	71522-71553	7	0.781
NC_011296_2	2.6\|632426\|32\|NC_011296\|PILER-CR,CRISPRCasFinder,CRT	632426-632457	32	MK448755	Streptococcus phage Javan423, complete genome	13110-13141	7	0.781
NC_011296_2	2.6\|632426\|32\|NC_011296\|PILER-CR,CRISPRCasFinder,CRT	632426-632457	32	MK448756	Streptococcus phage Javan425, complete genome	13110-13141	7	0.781
NC_011296_5	5.7\|1929726\|36\|NC_011296\|PILER-CR,CRISPRCasFinder,CRT	1929726-1929761	36	NZ_CP033050	Virgibacillus halodenitrificans strain Bac324 plasmid unnamed, complete sequence	42706-42741	7	0.806
NC_011296_5	5.107\|1936305\|36\|NC_011296\|CRISPRCasFinder,CRT,PILER-CR	1936305-1936340	36	MN693017	Marine virus AFVG_117M34, complete genome	13367-13402	7	0.806
NC_011296_2	2.6\|632426\|32\|NC_011296\|PILER-CR,CRISPRCasFinder,CRT	632426-632457	32	NC_014633	Ilyobacter polytropus DSM 2926 plasmid pILYOP01, complete sequence	361728-361759	8	0.75
NC_011296_2	2.6\|632426\|32\|NC_011296\|PILER-CR,CRISPRCasFinder,CRT	632426-632457	32	GU080336	Sulfolobus turreted icosahedral virus 2, complete genome	1743-1774	8	0.75
NC_011296_2	2.12\|632853\|33\|NC_011296\|PILER-CR,CRISPRCasFinder,CRT	632853-632885	33	NZ_CP039285	Leptospira interrogans strain FMAS_AW1 plasmid pLiSL2, complete sequence	111726-111758	8	0.758
NC_011296_2	2.16\|633136\|35\|NC_011296\|PILER-CR,CRISPRCasFinder,CRT	633136-633170	35	NC_011892	Methylobacterium nodulans ORS 2060 plasmid pMNOD01, complete sequence	228734-228768	8	0.771
NC_011296_5	5.7\|1929726\|36\|NC_011296\|PILER-CR,CRISPRCasFinder,CRT	1929726-1929761	36	NZ_CP034168	Enterococcus avium strain 352 plasmid unnamed, complete sequence	41169-41204	8	0.778
NC_011296_2	2.6\|632426\|32\|NC_011296\|PILER-CR,CRISPRCasFinder,CRT	632426-632457	32	NZ_CP053952	Bacillus cereus strain FDAARGOS_798 plasmid unnamed1, complete sequence	278683-278714	9	0.719
NC_011296_2	2.6\|632426\|32\|NC_011296\|PILER-CR,CRISPRCasFinder,CRT	632426-632457	32	NZ_CP029750	Staphylococcus aureus strain Smith plasmid pSS41, complete sequence	39430-39461	9	0.719
NC_011296_2	2.6\|632426\|32\|NC_011296\|PILER-CR,CRISPRCasFinder,CRT	632426-632457	32	NZ_CP053949	Bacillus cereus strain FDAARGOS_799 plasmid unnamed1, complete sequence	408833-408864	9	0.719
NC_011296_2	2.6\|632426\|32\|NC_011296\|PILER-CR,CRISPRCasFinder,CRT	632426-632457	32	NC_007021	Staphylococcus phage Twort, complete genome	96050-96081	9	0.719
NC_011296_2	2.6\|632426\|32\|NC_011296\|PILER-CR,CRISPRCasFinder,CRT	632426-632457	32	MN693506	Marine virus AFVG_25M112, complete genome	38693-38724	9	0.719
NC_011296_2	2.6\|632426\|32\|NC_011296\|PILER-CR,CRISPRCasFinder,CRT	632426-632457	32	MT151386	Staphylococcus virus Twort, complete genome	7873-7904	9	0.719
NC_011296_2	2.6\|632426\|32\|NC_011296\|PILER-CR,CRISPRCasFinder,CRT	632426-632457	32	MT151386	Staphylococcus virus Twort, complete genome	138411-138442	9	0.719
NC_011296_2	2.9\|632638\|35\|NC_011296\|PILER-CR,CRISPRCasFinder,CRT	632638-632672	35	KM514685	Lactobacillus phage Ldl1, complete genome	70493-70527	9	0.743
NC_011296_2	2.9\|632638\|35\|NC_011296\|PILER-CR,CRISPRCasFinder,CRT	632638-632672	35	NZ_CP039703	Clostridium butyricum strain 29-1 plasmid p-butyl_plas_29-1, complete sequence	374973-375007	9	0.743
NC_011296_2	2.9\|632638\|35\|NC_011296\|PILER-CR,CRISPRCasFinder,CRT	632638-632672	35	NZ_CP039706	Clostridium butyricum strain 4-1 plasmid p-butyl_plas_4-1, complete sequence	301007-301041	9	0.743
NC_011296_2	2.9\|632638\|35\|NC_011296\|PILER-CR,CRISPRCasFinder,CRT	632638-632672	35	NZ_CP033246	Clostridium butyricum strain CFSA3987 plasmid pCFSA3987, complete sequence	4009-4043	9	0.743
NC_011296_2	2.9\|632638\|35\|NC_011296\|PILER-CR,CRISPRCasFinder,CRT	632638-632672	35	NZ_CP033248	Clostridium butyricum strain CFSA3989 plasmid pCFSA3989, complete sequence	4051-4085	9	0.743
NC_011296_2	2.9\|632638\|35\|NC_011296\|PILER-CR,CRISPRCasFinder,CRT	632638-632672	35	NZ_CP013238	Clostridium butyricum strain CDC_51208 plasmid pNPD4_2, complete sequence	489556-489590	9	0.743
NC_011296_2	2.9\|632638\|35\|NC_011296\|PILER-CR,CRISPRCasFinder,CRT	632638-632672	35	NZ_AP019717	Clostridium butyricum strain NBRC 13949 plasmid pCBU1, complete sequence	336017-336051	9	0.743
NC_011296_2	2.9\|632638\|35\|NC_011296\|PILER-CR,CRISPRCasFinder,CRT	632638-632672	35	NZ_LR214986	Mycoplasma cynos strain NCTC10142 plasmid 13	189210-189244	9	0.743
NC_011296_2	2.12\|632853\|33\|NC_011296\|PILER-CR,CRISPRCasFinder,CRT	632853-632885	33	NC_020478	Bacillus phage Andromeda, complete genome	7760-7792	9	0.727
NC_011296_2	2.12\|632853\|33\|NC_011296\|PILER-CR,CRISPRCasFinder,CRT	632853-632885	33	KC330681	Bacillus phage Gemini, complete genome	7760-7792	9	0.727
NC_011296_2	2.12\|632853\|33\|NC_011296\|PILER-CR,CRISPRCasFinder,CRT	632853-632885	33	KC330679	Bacillus phage Curly, complete genome	7771-7803	9	0.727
NC_011296_2	2.12\|632853\|33\|NC_011296\|PILER-CR,CRISPRCasFinder,CRT	632853-632885	33	MT514532	Bacillus phage Bolokhovo, complete genome	7954-7986	9	0.727
NC_011296_2	2.12\|632853\|33\|NC_011296\|PILER-CR,CRISPRCasFinder,CRT	632853-632885	33	NC_025151	Leptospira interrogans serovar Lai str. 56601 plasmid Laicp, complete sequence	62613-62645	9	0.727
NC_011296_2	2.12\|632853\|33\|NC_011296\|PILER-CR,CRISPRCasFinder,CRT	632853-632885	33	NZ_CP006726	Leptospira interrogans serovar Linhai str. 56609 plasmid lcp2, complete sequence	3164-3196	9	0.727
NC_011296_2	2.16\|633136\|35\|NC_011296\|PILER-CR,CRISPRCasFinder,CRT	633136-633170	35	NZ_CP013615	Clostridium perfringens strain JP838 plasmid pJFP838A, complete sequence	283839-283873	9	0.743
NC_011296_5	5.50\|1932555\|40\|NC_011296\|PILER-CR,CRISPRCasFinder,CRT	1932555-1932594	40	MN694061	Marine virus AFVG_250M743, complete genome	12151-12190	9	0.775
NC_011296_5	5.72\|1934006\|36\|NC_011296\|CRISPRCasFinder,CRT,PILER-CR	1934006-1934041	36	MN693406	Marine virus AFVG_25M259, complete genome	43730-43765	9	0.75
NC_011296_5	5.113\|1936696\|37\|NC_011296\|CRISPRCasFinder,CRT,PILER-CR	1936696-1936732	37	NZ_CP012655	Lactobacillus plantarum strain HFC8 isolate Lactobacillus plantarum plasmid pMK02, complete sequence	20449-20485	9	0.757
NC_011296_2	2.6\|632426\|32\|NC_011296\|PILER-CR,CRISPRCasFinder,CRT	632426-632457	32	MN693546	Marine virus AFVG_25M34, complete genome	37916-37947	10	0.688
NC_011296_5	5.1\|1929334\|37\|NC_011296\|PILER-CR,CRISPRCasFinder,CRT	1929334-1929370	37	NZ_CP006684	Melissococcus plutonius S1 plasmid pMEPL_178, complete sequence	1250-1286	10	0.73
NC_011296_5	5.1\|1929334\|37\|NC_011296\|PILER-CR,CRISPRCasFinder,CRT	1929334-1929370	37	NZ_AP021886	Melissococcus plutonius strain DAT1033 plasmid pMP1, complete sequence	1250-1286	10	0.73
NC_011296_5	5.1\|1929334\|37\|NC_011296\|PILER-CR,CRISPRCasFinder,CRT	1929334-1929370	37	NZ_AP018525	Melissococcus plutonius strain DAT585 plasmid pMP1, complete sequence	1250-1286	10	0.73
NC_011296_5	5.1\|1929334\|37\|NC_011296\|PILER-CR,CRISPRCasFinder,CRT	1929334-1929370	37	NC_018265	Melissococcus plutonius DAT561 plasmid 1, complete sequence	197790-197826	10	0.73
NC_011296_5	5.66\|1933612\|36\|NC_011296\|CRISPRCasFinder,CRT,PILER-CR	1933612-1933647	36	MK448951	Streptococcus phage Javan470, complete genome	24287-24322	10	0.722
NC_011296_5	5.66\|1933612\|36\|NC_011296\|CRISPRCasFinder,CRT,PILER-CR	1933612-1933647	36	MK496824	Capybara microvirus Cap3_SP_646, complete genome	3351-3386	10	0.722
NC_011296_2	2.20\|633422\|34\|NC_011296\|PILER-CR,CRISPRCasFinder,CRT	633422-633455	34	CP011076	Brevibacillus laterosporus strain B9 plasmid unnamed2, complete sequence	763285-763318	11	0.676
NC_011296_5	5.33\|1931440\|36\|NC_011296\|PILER-CR,CRISPRCasFinder,CRT	1931440-1931475	36	NZ_CP009044	Campylobacter iguaniorum strain 1485E plasmid pCIG1485E, complete sequence	61949-61984	11	0.694
NC_011296_5	5.37\|1931700\|35\|NC_011296\|PILER-CR,CRISPRCasFinder,CRT	1931700-1931734	35	MT647606	Pelagibacter phage Mosig EXVC030M, partial genome	73733-73767	11	0.686

1. spacer 2.6|632426|32|NC_011296|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP009417 (Jeotgalibacillus malaysiensis strain malaysiensis plasmid unnamed, complete sequence) position: , mismatch: 7, identity: 0.781

tttttcttttttacaatattctctacttcttt	CRISPR spacer
tttttctttttcacaattttctctagtaccac	Protospacer
***********.***** ******* * *. .

2. spacer 2.6|632426|32|NC_011296|PILER-CR,CRISPRCasFinder,CRT matches to NC_047948 (Staphylococcus phage phiSA_BS2, complete genome) position: , mismatch: 7, identity: 0.781

tttttcttttttacaatattctctacttcttt	CRISPR spacer
gttttcttttttacaaaattctcttttaatat	Protospacer
 *************** ******* .*  * *

3. spacer 2.6|632426|32|NC_011296|PILER-CR,CRISPRCasFinder,CRT matches to MH078572 (Staphylococcus phage phiSA_BS1, complete genome) position: , mismatch: 7, identity: 0.781

tttttcttttttacaatattctctacttcttt	CRISPR spacer
gttttcttttttacaaaattctcttttaatat	Protospacer
 *************** ******* .*  * *

4. spacer 2.6|632426|32|NC_011296|PILER-CR,CRISPRCasFinder,CRT matches to MN582070 (Myoviridae sp. ctThM1, complete genome) position: , mismatch: 7, identity: 0.781

tttttcttttttacaatattctctacttcttt	CRISPR spacer
tttgcagcttttagaatcttctctacttcttt	Protospacer
*** .  .***** *** **************

5. spacer 2.6|632426|32|NC_011296|PILER-CR,CRISPRCasFinder,CRT matches to MK448755 (Streptococcus phage Javan423, complete genome) position: , mismatch: 7, identity: 0.781

tttttcttttttacaatattctctacttcttt	CRISPR spacer
tttttcttttttccaatcttctccgaattttt	Protospacer
************ **** *****..  *.***

6. spacer 2.6|632426|32|NC_011296|PILER-CR,CRISPRCasFinder,CRT matches to MK448756 (Streptococcus phage Javan425, complete genome) position: , mismatch: 7, identity: 0.781

tttttcttttttacaatattctctacttcttt	CRISPR spacer
tttttcttttttccaatcttctccgaattttt	Protospacer
************ **** *****..  *.***

7. spacer 5.7|1929726|36|NC_011296|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP033050 (Virgibacillus halodenitrificans strain Bac324 plasmid unnamed, complete sequence) position: , mismatch: 7, identity: 0.806

attgagaagaaaagcagaaagagaattatttttaga	CRISPR spacer
aagacgaagaaaagcagaaaaagaactatttttagg	Protospacer
*  . ***************.****.*********.

8. spacer 5.107|1936305|36|NC_011296|CRISPRCasFinder,CRT,PILER-CR matches to MN693017 (Marine virus AFVG_117M34, complete genome) position: , mismatch: 7, identity: 0.806

tggtgcaggtggctctggtggagctgcgggctctgc	CRISPR spacer
tggtggaggtggctttggtggagctggtggtaatgc	Protospacer
***** ********.***********  **.  ***

9. spacer 2.6|632426|32|NC_011296|PILER-CR,CRISPRCasFinder,CRT matches to NC_014633 (Ilyobacter polytropus DSM 2926 plasmid pILYOP01, complete sequence) position: , mismatch: 8, identity: 0.75

tttttcttttttacaatattctctacttcttt	CRISPR spacer
tacaatatttttacaatattttttacttcttt	Protospacer
* .  . *************.*.*********

10. spacer 2.6|632426|32|NC_011296|PILER-CR,CRISPRCasFinder,CRT matches to GU080336 (Sulfolobus turreted icosahedral virus 2, complete genome) position: , mismatch: 8, identity: 0.75

tttttcttttttacaatattctctacttcttt	CRISPR spacer
tctttcttttttataatatactctatccatct	Protospacer
*.***********.***** *****... *.*

11. spacer 2.12|632853|33|NC_011296|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP039285 (Leptospira interrogans strain FMAS_AW1 plasmid pLiSL2, complete sequence) position: , mismatch: 8, identity: 0.758

ccatttttacctccctttttggttttgtaaaaa	CRISPR spacer
acaagttcaccgccctttttggttttgtattac	Protospacer
 **  **.*** *****************  *

12. spacer 2.16|633136|35|NC_011296|PILER-CR,CRISPRCasFinder,CRT matches to NC_011892 (Methylobacterium nodulans ORS 2060 plasmid pMNOD01, complete sequence) position: , mismatch: 8, identity: 0.771

ttaatccataagttatattgtcttctttaaaataa	CRISPR spacer
gtaatccaaaagttatattttcttctacaagttta	Protospacer
 ******* ********** ****** .**. * *

13. spacer 5.7|1929726|36|NC_011296|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP034168 (Enterococcus avium strain 352 plasmid unnamed, complete sequence) position: , mismatch: 8, identity: 0.778

attgagaagaaaagcagaaagagaattatttttaga	CRISPR spacer
tatggaagaaaaagaaaaaagagaattatttttaga	Protospacer
  **..*..***** *.*******************

14. spacer 2.6|632426|32|NC_011296|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP053952 (Bacillus cereus strain FDAARGOS_798 plasmid unnamed1, complete sequence) position: , mismatch: 9, identity: 0.719

tttttcttttttacaatattctctacttcttt	CRISPR spacer
aatgcactgtttacaatactccctacttcttt	Protospacer
  * . .* *********.**.**********

15. spacer 2.6|632426|32|NC_011296|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP029750 (Staphylococcus aureus strain Smith plasmid pSS41, complete sequence) position: , mismatch: 9, identity: 0.719

tttttcttttttacaatattctc------tacttcttt	CRISPR spacer
tttttattttttacagtattctcgtagaataa------	Protospacer
***** *********.*******      **

16. spacer 2.6|632426|32|NC_011296|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP053949 (Bacillus cereus strain FDAARGOS_799 plasmid unnamed1, complete sequence) position: , mismatch: 9, identity: 0.719

tttttcttttttacaatattctctacttcttt	CRISPR spacer
aatgcactgtttacaatactccctacttcttt	Protospacer
  * . .* *********.**.**********

17. spacer 2.6|632426|32|NC_011296|PILER-CR,CRISPRCasFinder,CRT matches to NC_007021 (Staphylococcus phage Twort, complete genome) position: , mismatch: 9, identity: 0.719

tttttcttttttacaatattctctacttcttt	CRISPR spacer
catttcttttttagaattttctctaatacaag	Protospacer
. *********** *** ******* * *

18. spacer 2.6|632426|32|NC_011296|PILER-CR,CRISPRCasFinder,CRT matches to MN693506 (Marine virus AFVG_25M112, complete genome) position: , mismatch: 9, identity: 0.719

tttttcttttttacaatattctctacttcttt	CRISPR spacer
cttttcttttttgcaataatctctggatcaaa	Protospacer
.***********.***** *****.  **

19. spacer 2.6|632426|32|NC_011296|PILER-CR,CRISPRCasFinder,CRT matches to MT151386 (Staphylococcus virus Twort, complete genome) position: , mismatch: 9, identity: 0.719

tttttcttttttacaatattctctacttcttt	CRISPR spacer
catttcttttttagaattttctctaatacaag	Protospacer
. *********** *** ******* * *

20. spacer 2.6|632426|32|NC_011296|PILER-CR,CRISPRCasFinder,CRT matches to MT151386 (Staphylococcus virus Twort, complete genome) position: , mismatch: 9, identity: 0.719

tttttcttttttacaatattctctacttcttt	CRISPR spacer
catttcttttttagaattttctctaatacaag	Protospacer
. *********** *** ******* * *

21. spacer 2.9|632638|35|NC_011296|PILER-CR,CRISPRCasFinder,CRT matches to KM514685 (Lactobacillus phage Ldl1, complete genome) position: , mismatch: 9, identity: 0.743

caatttcaattaattctttcattttcccctccgat	CRISPR spacer
caattttaattaattctttcattttagttctctct	Protospacer
******.******************  ....*  *

22. spacer 2.9|632638|35|NC_011296|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP039703 (Clostridium butyricum strain 29-1 plasmid p-butyl_plas_29-1, complete sequence) position: , mismatch: 9, identity: 0.743

caatttcaattaattctttcattttcccctccgat	CRISPR spacer
tactttcaattaattcttgcatttttccagctgga	Protospacer
.* *************** ******.**  *.*.

23. spacer 2.9|632638|35|NC_011296|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP039706 (Clostridium butyricum strain 4-1 plasmid p-butyl_plas_4-1, complete sequence) position: , mismatch: 9, identity: 0.743

caatttcaattaattctttcattttcccctccgat	CRISPR spacer
tactttcaattaattcttgcatttttccagctgga	Protospacer
.* *************** ******.**  *.*.

24. spacer 2.9|632638|35|NC_011296|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP033246 (Clostridium butyricum strain CFSA3987 plasmid pCFSA3987, complete sequence) position: , mismatch: 9, identity: 0.743

caatttcaattaattctttcattttcccctccgat	CRISPR spacer
tactttcaattaattcttgcatttttccagctgga	Protospacer
.* *************** ******.**  *.*.

25. spacer 2.9|632638|35|NC_011296|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP033248 (Clostridium butyricum strain CFSA3989 plasmid pCFSA3989, complete sequence) position: , mismatch: 9, identity: 0.743

caatttcaattaattctttcattttcccctccgat	CRISPR spacer
tactttcaattaattcttgcatttttccagctgga	Protospacer
.* *************** ******.**  *.*.

26. spacer 2.9|632638|35|NC_011296|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP013238 (Clostridium butyricum strain CDC_51208 plasmid pNPD4_2, complete sequence) position: , mismatch: 9, identity: 0.743

caatttcaattaattctttcattttcccctccgat	CRISPR spacer
tactttcaattaattcttgcatttttccagctgga	Protospacer
.* *************** ******.**  *.*.

27. spacer 2.9|632638|35|NC_011296|PILER-CR,CRISPRCasFinder,CRT matches to NZ_AP019717 (Clostridium butyricum strain NBRC 13949 plasmid pCBU1, complete sequence) position: , mismatch: 9, identity: 0.743

caatttcaattaattctttcattttcccctccgat	CRISPR spacer
tactttcaattaattcttgcatttttccagctgga	Protospacer
.* *************** ******.**  *.*.

28. spacer 2.9|632638|35|NC_011296|PILER-CR,CRISPRCasFinder,CRT matches to NZ_LR214986 (Mycoplasma cynos strain NCTC10142 plasmid 13) position: , mismatch: 9, identity: 0.743

caatttcaattaattctttcattttccc--ctccgat	CRISPR spacer
cattttcaattaattcattcatttttataacttca--	Protospacer
** ************* ********. .  **.*.

29. spacer 2.12|632853|33|NC_011296|PILER-CR,CRISPRCasFinder,CRT matches to NC_020478 (Bacillus phage Andromeda, complete genome) position: , mismatch: 9, identity: 0.727

ccatttttacctccctttttggttttgtaaaaa	CRISPR spacer
ttctttttagctccctttttgtttttggcatac	Protospacer
.. ****** *********** *****  * *

30. spacer 2.12|632853|33|NC_011296|PILER-CR,CRISPRCasFinder,CRT matches to KC330681 (Bacillus phage Gemini, complete genome) position: , mismatch: 9, identity: 0.727

ccatttttacctccctttttggttttgtaaaaa	CRISPR spacer
ttctttttagctccctttttgtttttggcatac	Protospacer
.. ****** *********** *****  * *

31. spacer 2.12|632853|33|NC_011296|PILER-CR,CRISPRCasFinder,CRT matches to KC330679 (Bacillus phage Curly, complete genome) position: , mismatch: 9, identity: 0.727

ccatttttacctccctttttggttttgtaaaaa	CRISPR spacer
ttctttttagctccctttttgtttttggcatac	Protospacer
.. ****** *********** *****  * *

32. spacer 2.12|632853|33|NC_011296|PILER-CR,CRISPRCasFinder,CRT matches to MT514532 (Bacillus phage Bolokhovo, complete genome) position: , mismatch: 9, identity: 0.727

ccatttttacctccctttttggttttgtaaaaa	CRISPR spacer
ttctttttagctccctttttgtttttggcatac	Protospacer
.. ****** *********** *****  * *

33. spacer 2.12|632853|33|NC_011296|PILER-CR,CRISPRCasFinder,CRT matches to NC_025151 (Leptospira interrogans serovar Lai str. 56601 plasmid Laicp, complete sequence) position: , mismatch: 9, identity: 0.727

ccatttttacctccctttttggttttgtaaaaa	CRISPR spacer
gaaagttcaccgccctttttggttttgtattac	Protospacer
  *  **.*** *****************  *

34. spacer 2.12|632853|33|NC_011296|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP006726 (Leptospira interrogans serovar Linhai str. 56609 plasmid lcp2, complete sequence) position: , mismatch: 9, identity: 0.727

ccatttttacctccctttttggttttgtaaaaa	CRISPR spacer
gaaagttcaccgccctttttggttttgtattac	Protospacer
  *  **.*** *****************  *

35. spacer 2.16|633136|35|NC_011296|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP013615 (Clostridium perfringens strain JP838 plasmid pJFP838A, complete sequence) position: , mismatch: 9, identity: 0.743

ttaatccataagttatattgtcttctttaaaataa	CRISPR spacer
tatatacataagttatattatcttcttttataggt	Protospacer
*  ** *************.******** * * .

36. spacer 5.50|1932555|40|NC_011296|PILER-CR,CRISPRCasFinder,CRT matches to MN694061 (Marine virus AFVG_250M743, complete genome) position: , mismatch: 9, identity: 0.775

caactgtaactgttaaagatggtgaaaccactgctattgt	CRISPR spacer
ctaatgtaactgttaaagatggtggaacaactacattaga	Protospacer
* * ********************.*** ***.*  * *

37. spacer 5.72|1934006|36|NC_011296|CRISPRCasFinder,CRT,PILER-CR matches to MN693406 (Marine virus AFVG_25M259, complete genome) position: , mismatch: 9, identity: 0.75

gttcaacaaactctttgtgtttgattttattgacaa	CRISPR spacer
cttcaacaaactctttatgtttgttttgacgaagca	Protospacer
 ***************.****** *** *. .*  *

38. spacer 5.113|1936696|37|NC_011296|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP012655 (Lactobacillus plantarum strain HFC8 isolate Lactobacillus plantarum plasmid pMK02, complete sequence) position: , mismatch: 9, identity: 0.757

agacaggctt-----tgttggaagtttgacggggagagtatt	CRISPR spacer
-----agtttcagggtgttggaaatttgatggggagagtatt	Protospacer
     .*.**     ********.*****.************

39. spacer 2.6|632426|32|NC_011296|PILER-CR,CRISPRCasFinder,CRT matches to MN693546 (Marine virus AFVG_25M34, complete genome) position: , mismatch: 10, identity: 0.688

tttttcttttttacaatattctctacttcttt	CRISPR spacer
actttctttttgacagtattctctatgaagta	Protospacer
 .********* ***.*********.    *

40. spacer 5.1|1929334|37|NC_011296|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP006684 (Melissococcus plutonius S1 plasmid pMEPL_178, complete sequence) position: , mismatch: 10, identity: 0.73

aggatttaatcttttcaaaaatctgtctaacccactg	CRISPR spacer
ttgttttaatctttttaaaagtctgtctaaagttctt	Protospacer
  * ***********.****.*********  . **

41. spacer 5.1|1929334|37|NC_011296|PILER-CR,CRISPRCasFinder,CRT matches to NZ_AP021886 (Melissococcus plutonius strain DAT1033 plasmid pMP1, complete sequence) position: , mismatch: 10, identity: 0.73

aggatttaatcttttcaaaaatctgtctaacccactg	CRISPR spacer
ttgttttaatctttttaaaagtctgtctaaagttctt	Protospacer
  * ***********.****.*********  . **

42. spacer 5.1|1929334|37|NC_011296|PILER-CR,CRISPRCasFinder,CRT matches to NZ_AP018525 (Melissococcus plutonius strain DAT585 plasmid pMP1, complete sequence) position: , mismatch: 10, identity: 0.73

aggatttaatcttttcaaaaatctgtctaacccactg	CRISPR spacer
ttgttttaatctttttaaaagtctgtctaaagttctt	Protospacer
  * ***********.****.*********  . **

43. spacer 5.1|1929334|37|NC_011296|PILER-CR,CRISPRCasFinder,CRT matches to NC_018265 (Melissococcus plutonius DAT561 plasmid 1, complete sequence) position: , mismatch: 10, identity: 0.73

aggatttaatcttttcaaaaatctgtctaacccactg	CRISPR spacer
ttgttttaatctttttaaaagtctgtctaaagttctt	Protospacer
  * ***********.****.*********  . **

44. spacer 5.66|1933612|36|NC_011296|CRISPRCasFinder,CRT,PILER-CR matches to MK448951 (Streptococcus phage Javan470, complete genome) position: , mismatch: 10, identity: 0.722

aattttatactttgcaaattctgttttttatgtttg	CRISPR spacer
gaatttatcctttgcaacttctgttttttcaccctt	Protospacer
.* ***** ******** ***********   ..*

45. spacer 5.66|1933612|36|NC_011296|CRISPRCasFinder,CRT,PILER-CR matches to MK496824 (Capybara microvirus Cap3_SP_646, complete genome) position: , mismatch: 10, identity: 0.722

aattttatactttgcaaattctgttttttatgtttg	CRISPR spacer
tgttcgtatttttgcaaattctatttttaatgtttg	Protospacer
 .**.    .************.***** *******

46. spacer 2.20|633422|34|NC_011296|PILER-CR,CRISPRCasFinder,CRT matches to CP011076 (Brevibacillus laterosporus strain B9 plasmid unnamed2, complete sequence) position: , mismatch: 11, identity: 0.676

ggcttttcctttgcagcatcaattgctgcaactt	CRISPR spacer
caaattgcctttgctgcatcaattgctgatccgc	Protospacer
 .  ** ******* *************   * .

47. spacer 5.33|1931440|36|NC_011296|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP009044 (Campylobacter iguaniorum strain 1485E plasmid pCIG1485E, complete sequence) position: , mismatch: 11, identity: 0.694

tttaataaataatgctaatatttcattaaaagcaaa	CRISPR spacer
tagaataaataatgctaaaatttgattaagtttttg	Protospacer
*  *************** **** *****.  .  .

48. spacer 5.37|1931700|35|NC_011296|PILER-CR,CRISPRCasFinder,CRT matches to MT647606 (Pelagibacter phage Mosig EXVC030M, partial genome) position: , mismatch: 11, identity: 0.686

ggagttgatggatttatataattatcaggactcga	CRISPR spacer
caaactgatggatttatttacttatcaggaacatc	Protospacer
 .*..************ ** ********* .

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

450328 : 459941

Tupanvirus(28.57%)

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_164924893.1\|450328_451303_+	UDP-glucose 4-epimerase GalE	A0A2K9L5H6	Tupanvirus	4.1e-57	40.9
WP_012546080.1\|451664_452819_+	GDP-mannose 4,6-dehydratase	M1HGM9	Acanthocystis_turfacea_Chlorella_virus	1.7e-118	59.7
WP_012544929.1\|453390_454590_+	GDP-L-fucose synthase	M4R1H4	Synechococcus_phage	1.6e-87	46.3
WP_012545566.1\|454805_455753_+	SDR family oxidoreductase	A0A2K9KZK0	Tupanvirus	4.4e-88	49.8
WP_012546142.1\|455757_456828_+	NAD-dependent epimerase/dehydratase family protein	M1GXM0	Acanthocystis_turfacea_Chlorella_virus	1.5e-15	25.2
WP_012545331.1\|456845_457907_+	NAD-dependent epimerase/dehydratase family protein	H8ZJ37	Ostreococcus_tauri_virus	4.2e-15	27.0
WP_164924813.1\|457981_459352_+	oligosaccharide flippase family protein	NA	NA	NA	NA
WP_012546131.1\|459338_459941_+	adenylyl-sulfate kinase	A0A1B0XTK9	Freshwater_phage	1.4e-07	30.4

DBSCAN-SWA_2

593386 : 601586

Bacillus_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_012546125.1\|593386_594031_-	response regulator transcription factor	W8CYM9	Bacillus_phage	1.0e-19	30.6
WP_012545192.1\|594120_595743_-	chaperonin GroEL	A0A240F779	uncultured_virus	2.1e-170	58.6
WP_012546861.1\|595759_596026_-	co-chaperone GroES	A0A221S4G8	uncultured_virus	4.0e-15	52.9
WP_012546425.1\|596359_597571_+	lytic transglycosylase domain-containing protein	A0A0S2SXN2	Bacillus_phage	2.2e-12	38.9
WP_012544965.1\|597567_598170_-	tetratricopeptide repeat protein	NA	NA	NA	NA
WP_012545579.1\|598166_598817_-	histidinol phosphate phosphatase domain-containing protein	NA	NA	NA	NA
WP_012545477.1\|598813_599374_-	isochorismatase family protein	NA	NA	NA	NA
WP_012546622.1\|599374_599749_-	response regulator	W8CYM9	Bacillus_phage	4.8e-14	43.7
WP_164924824.1\|599729_601586_-	cell wall metabolism sensor histidine kinase WalK	A0A1V0SGX0	Hokovirus	3.8e-27	28.4

DBSCAN-SWA_3

1418376 : 1429048

Bacillus_virus(33.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_012544942.1\|1418376_1419048_-	cell division ATP-binding protein FtsE	G9BWD6	Planktothrix_phage	2.8e-28	35.3
WP_038059428.1\|1419044_1419968_-	transketolase family protein	NA	NA	NA	NA
WP_164924858.1\|1420014_1420842_-	transketolase	A0A2K9L6P9	Tupanvirus	4.6e-33	30.7
WP_012545544.1\|1420922_1423439_+	DNA polymerase I	A0A218MKQ4	uncultured_virus	2.1e-52	31.9
WP_012546417.1\|1423451_1424765_-	insulinase family protein	G3MBJ8	Bacillus_virus	1.8e-31	25.5
WP_012545053.1\|1424761_1426057_-	insulinase family protein	G3MBJ8	Bacillus_virus	2.8e-45	29.3
WP_012546385.1\|1426053_1426413_-	response regulator	NA	NA	NA	NA
WP_012544939.1\|1426393_1429048_-	PAS domain S-box protein	W8CYF6	Bacillus_phage	1.3e-20	29.9

DBSCAN-SWA_4

1841776 : 1849219

Indivirus(16.67%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_012546570.1\|1841776_1842427_+	ABC transporter ATP-binding protein	A0A1V0SE00	Indivirus	1.1e-16	30.6
WP_012546620.1\|1842430_1843753_-	signal recognition particle protein	D6PHS7	uncultured_phage	3.8e-05	29.6
WP_028842055.1\|1843753_1844251_-	redoxin domain-containing protein	NA	NA	NA	NA
WP_012545412.1\|1844254_1844587_-	thioredoxin	A0A1X9I9P5	Staphylococcus_phage	2.6e-19	39.4
WP_012546164.1\|1844695_1845145_-	Hsp20/alpha crystallin family protein	A0A1B2LRT2	Wolbachia_phage	5.9e-11	28.2
WP_012546043.1\|1845166_1847797_-	ATP-dependent chaperone ClpB	H6X3M6	Enterobacteria_phage	9.8e-122	32.2
WP_012545092.1\|1847810_1848149_-	MerR family transcriptional regulator	NA	NA	NA	NA
WP_012546226.1\|1848151_1849219_-	molecular chaperone DnaJ	E3T4P7	Cafeteria_roenbergensis_virus	2.8e-27	30.7

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. NC_011296

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection