CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Target MGE spacer number	Prophage number
NC_011370	Rhizobium leguminosarum bv. trifolii WSM2304 plasmid pRLG203, complete sequence	0 crisprs	NA	0	0
NC_011371	Rhizobium leguminosarum bv. trifolii WSM2304 plasmid pRLG204, complete sequence	0 crisprs	NA	0	0
NC_011369	Rhizobium leguminosarum bv. trifolii WSM2304, complete sequence	3 crisprs	cas3,csa3,WYL,DEDDh	1	6
NC_011368	Rhizobium leguminosarum bv. trifolii WSM2304 plasmid pRLG201, complete sequence	0 crisprs	csa3	0	0
NC_011366	Rhizobium leguminosarum bv. trifolii WSM2304 plasmid pRLG202, complete sequence	0 crisprs	DEDDh,csa3,WYL	0	0

Results visualization

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CRISPR-Cas detection and classification

Crispr_ID: NC_011369_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_011369_1

562025-562107

Orphan

Consensus_repeat	Method
GTAGCGGTTCCGGGATAACGACAT	CRISPRCasFinder

1 spacers

The CRISPR arrays of NC_011369_1

>merge|NC_011369|1|562025-562107|CRISPRCasFinder
GTAGCGGTTCCGGGATAACGACATGCATCAAACATCCAGAGCATGTCGCCCGGAAGTGCGTAGCGGTTCCGGGATAACGACAT

>NC_011369|1|1|562025-562107|CRISPRCasFinder
GTAGCGGTTCCGGGATAACGACAT	GCATCAAACATCCAGAGCATGTCGCCCGGAAGTGC
GTAGCGGTTCCGGGATAACGACAT

Protein	Signature genes	Signature genes Name	Protein_function
NC_011369.1\|WP_012556759.1\|547622_549557_+\|DUF2207-domain-containing-protein	unknown	unknown	gnl\|CDD\|378333
NC_011369.1\|WP_012556762.1\|551893_553711_+\|cache-domain-containing-protein	unknown	unknown	gnl\|CDD\|214599
NC_011369.1\|WP_003588195.1\|559137_560397_+\|class-I-SAM-dependent-methyltransferase	unknown	unknown	gnl\|CDD\|225139
NC_011369.1\|WP_012556773.1\|571134_572379_+\|aromatic-ring-hydroxylating-dioxygenase-subunit-alpha	unknown	unknown	gnl\|CDD\|226985
NC_011369.1\|WP_012556771.1\|569059_570034_-\|threonylcarbamoyl-AMP-synthase	unknown	unknown	gnl\|CDD\|223088
NC_011369.1\|WP_012556775.1\|573693_574839_-\|IS4-family-transposase	unknown	unknown	gnl\|CDD\|372999
NC_011369.1\|WP_012556760.1\|549622_550906_+\|phosphoribosylamine--glycine-ligase	unknown	unknown	gnl\|CDD\|234856
NC_011369.1\|WP_012556769.1\|564070_567406_+\|DUF1217-domain-containing-protein	unknown	unknown	gnl\|CDD\|369062
NC_011369.1\|WP_012556767.1\|562165_563125_+\|4-hydroxybenzoate-octaprenyltransferase	unknown	unknown	gnl\|CDD\|183808
NC_011369.1\|WP_012556761.1\|550999_551461_+\|hypothetical-protein	unknown	unknown	unknown
NC_011369.1\|WP_012556768.1\|563206_563773_-\|hypothetical-protein	unknown	unknown	unknown
NC_011369.1\|WP_012556770.1\|567586_569023_-\|FAD-binding-oxidoreductase	unknown	unknown	gnl\|CDD\|223354
NC_011369.1\|WP_012556758.1\|546323_547586_+\|3-phosphoshikimate-1-carboxyvinyltransferase	unknown	unknown	gnl\|CDD\|238797
NC_011369.1\|WP_012556766.1\|561186_561999_+\|MipA/OmpV-family-protein	unknown	unknown	gnl\|CDD\|226236
NC_011369.1\|WP_012556764.1\|556694_559004_+\|RNA-binding-transcriptional-accessory-protein	unknown	unknown	gnl\|CDD\|225094
NC_011369.1\|WP_012556765.1\|560432_561014_+\|histidine-phosphatase-family-protein	unknown	unknown	gnl\|CDD\|366010
NC_011369.1\|WP_003588177.1\|573051_573315_-\|DUF982-domain-containing-protein	unknown	unknown	gnl\|CDD\|368772
NC_011369.1\|WP_012556772.1\|570122_570731_-\|hypothetical-protein	unknown	unknown	unknown
NC_011369.1\|WP_012556763.1\|554082_556266_-\|glycine--tRNA-ligase-subunit-beta	unknown	unknown	gnl\|CDD\|234925
NC_011369.1\|WP_012556774.1\|572516_572987_+\|BA14K-family-protein	unknown	unknown	gnl\|CDD\|369573

Protein	Function_ID	Function_description	E-value
NC_011369.1\|WP_012556771.1\|569059_570034_-\|threonylcarbamoyl-AMP-synthase	gnl\|CDD\|223088	COG0009, SUA5, Putative translation factor (SUA5) [Translation, ribosomal structure and biogenesis].	7.27277e-79
NC_011369.1\|WP_012556762.1\|551893_553711_+\|cache-domain-containing-protein	gnl\|CDD\|214599	smart00283, MA, Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer). Thought to undergo reversible methylation in response to attractants or repellants during bacterial chemotaxis.	8.81529e-65
NC_011369.1\|WP_003588195.1\|559137_560397_+\|class-I-SAM-dependent-methyltransferase	gnl\|CDD\|225139	COG2230, Cfa, Cyclopropane fatty acid synthase and related methyltransferases [Cell envelope biogenesis, outer membrane].	2.47882e-126
NC_011369.1\|WP_012556773.1\|571134_572379_+\|aromatic-ring-hydroxylating-dioxygenase-subunit-alpha	gnl\|CDD\|226985	COG4638, HcaE, Phenylpropionate dioxygenase and related ring-hydroxylating dioxygenases, large terminal subunit [Inorganic ion transport and metabolism / General function prediction only].	1.37864e-114
NC_011369.1\|WP_012556775.1\|573693_574839_-\|IS4-family-transposase	gnl\|CDD\|372999	pfam14294, DUF4372, Domain of unknown function (DUF4372). This domain family is found in bacteria, and is approximately 80 amino acids in length. The family is found in association with pfam01609. There is a single completely conserved residue G that may be functionally important.	1.65086e-27
NC_011369.1\|WP_012556760.1\|549622_550906_+\|phosphoribosylamine--glycine-ligase	gnl\|CDD\|234856	PRK00885, PRK00885, phosphoribosylamine--glycine ligase; Provisional.	0
NC_011369.1\|WP_012556769.1\|564070_567406_+\|DUF1217-domain-containing-protein	gnl\|CDD\|369062	pfam06748, DUF1217, Protein of unknown function (DUF1217). This family represents a conserved region that is found within bacterial proteins, most of which are hypothetical. Some members contain multiple copies.	7.63063e-56
NC_011369.1\|WP_012556767.1\|562165_563125_+\|4-hydroxybenzoate-octaprenyltransferase	gnl\|CDD\|183808	PRK12878, ubiA, 4-hydroxybenzoate octaprenyltransferase.	0
NC_011369.1\|WP_012556759.1\|547622_549557_+\|DUF2207-domain-containing-protein	gnl\|CDD\|378333	pfam09972, DUF2207, Predicted membrane protein (DUF2207). This domain, found in various hypothetical bacterial proteins, has no known function.	9.82853e-72
NC_011369.1\|WP_012556770.1\|567586_569023_-\|FAD-binding-oxidoreductase	gnl\|CDD\|223354	COG0277, GlcD, FAD/FMN-containing dehydrogenases [Energy production and conversion].	4.98858e-127
NC_011369.1\|WP_012556758.1\|546323_547586_+\|3-phosphoshikimate-1-carboxyvinyltransferase	gnl\|CDD\|238797	cd01556, EPSP_synthase, EPSP synthase domain. 3-phosphoshikimate 1-carboxyvinyltransferase (5-enolpyruvylshikimate-3-phosphate synthase) (EC 2.5.1.19) catalyses the reaction between shikimate-3-phosphate (S3P) and phosphoenolpyruvate (PEP) to form 5-enolpyruvylshkimate-3-phosphate (EPSP), an intermediate in the shikimate pathway leading to aromatic amino acid biosynthesis. The reaction is phosphoenolpyruvate + 3-phosphoshikimate = phosphate + 5-O-(1-carboxyvinyl)-3-phosphoshikimate. It is found in bacteria and plants but not animals. The enzyme is the target of the widely used herbicide glyphosate, which has been shown to occupy the active site. In bacteria and plants, it is a single domain protein, while in fungi, the domain is found as part of a multidomain protein with functions that are all part of the shikimate pathway.	3.13389e-138
NC_011369.1\|WP_012556766.1\|561186_561999_+\|MipA/OmpV-family-protein	gnl\|CDD\|226236	COG3713, OmpV, Outer membrane protein V [Cell envelope biogenesis, outer membrane].	4.46356e-61
NC_011369.1\|WP_012556764.1\|556694_559004_+\|RNA-binding-transcriptional-accessory-protein	gnl\|CDD\|225094	COG2183, Tex, Transcriptional accessory protein [Transcription].	0
NC_011369.1\|WP_012556765.1\|560432_561014_+\|histidine-phosphatase-family-protein	gnl\|CDD\|366010	pfam00300, His_Phos_1, Histidine phosphatase superfamily (branch 1). The histidine phosphatase superfamily is so named because catalysis centers on a conserved His residue that is transiently phosphorylated during the catalytic cycle. Other conserved residues contribute to a 'phosphate pocket' and interact with the phospho group of substrate before, during and after its transfer to the His residue. Structure and sequence analyses show that different families contribute different additional residues to the 'phosphate pocket' and, more surprisingly, differ in the position, in sequence and in three dimensions, of a catalytically essential acidic residue. The superfamily may be divided into two main branches. The larger branch 1 contains a wide variety of catalytic functions, the best known being fructose 2,6-bisphosphatase (found in a bifunctional protein with 2-phosphofructokinase) and cofactor-dependent phosphoglycerate mutase. The latter is an unusual example of a mutase activity in the superfamily: the vast majority of members appear to be phosphatases. The bacterial regulatory protein phosphatase SixA is also in branch 1 and has a minimal, and possible ancestral-like structure, lacking the large domain insertions that contribute to binding of small molecules in branch 1 members.	2.63629e-57
NC_011369.1\|WP_003588177.1\|573051_573315_-\|DUF982-domain-containing-protein	gnl\|CDD\|368772	pfam06169, DUF982, Protein of unknown function (DUF982). This family consists of several hypothetical proteins from Rhizobium meliloti, Rhizobium loti and Agrobacterium tumefaciens. The function of this family is unknown. Structural modelling suggests this domain may bind nucleic acids.	4.10304e-21
NC_011369.1\|WP_012556763.1\|554082_556266_-\|glycine--tRNA-ligase-subunit-beta	gnl\|CDD\|234925	PRK01233, glyS, glycyl-tRNA synthetase subunit beta; Validated.	0
NC_011369.1\|WP_012556774.1\|572516_572987_+\|BA14K-family-protein	gnl\|CDD\|369573	pfam07886, BA14K, BA14K-like protein. The sequences found in this family are similar to the BA14K proteins expressed by Brucella abortus and by Brucella suis. BA14K was found to be strongly immunoreactive; it induces both humoral and cellular responses in hosts throughout the infective process.	9.63535e-11

>NC_011369.1|WP_012556766.1|561186_561999_+|MipA/OmpV-family-protein
MSHRSIVSISLAIAFISFGSAAAQESGQHFWSGDWYLNVGVAGFSAPKFEGSSHNEFKFSPLISVGRQGAGPRFSSRNDNPSFALIDKGAFRAGIVGKFVPSRDDGDGHELKGLRKVKWGAEAGGFVEVYPTDFLRARAEVRQGIRSHDGVVADLAIDAFTDITPDLQLSGGPRATFATRGYYDAYYGVSAKHAAESGLDPYKPTAGMQSYGAGAALTWKATENLSASSFLEYKRLAGPAADSSLVRDRGSKNQVLIGVSATYKFNFSLQ
>NC_011369.1|WP_012556765.1|560432_561014_+|histidine-phosphatase-family-protein
MSSAFPEIYLVRHGETEWSLSGRHTGRSDIPLTGNGEAAASKLADRLSGLSFSAVWSSPSARARKTCALAGFGAGAVIRDDLAEWDYGAYEGVTTKAILAERPGWQLFRDGCPNGETSADVGARADAIIHALREAAGTILIFSSSHFLRVLAARWLGLPPEGGAHFVLDTASISVLGYEHDLTEPVIRRWNQR
>NC_011369.1|WP_003588195.1|559137_560397_+|class-I-SAM-dependent-methyltransferase
MASAFLSIVQQIIRKGSLKLTLANGDTYMIGDDTGDMVAARLADQEAEDAIRRDPTMKLGEMYMQGRFILEQGNIYDFLSLVKQNTTNEIFDFKMAALLVGRIAWQQLKSRVPVNRNKHNVAHHYDLSAKLFDLFLDEDWQYSCAYFEPPGIGLDEAQLAKKRHIAAKLLLEPNQRILEIGSGWGGMGMYLTEATEGAEFTGITLSEEQLKVSRSRAEKRGLAERVRFELQDYRTLTGRKFDRIVSVGMFEHVGIGNYPNFFRKVSDLLDDNGVMVLHSIGRPKPSFGTNAFIEKYIFPGGYIPSVGEVLPPLEKAGLLVRDVEILPLHYAYTLRHWRERFVARKAEAVALYDEQFFRMWEFYLAGSEMGFRWDELFILQIQIAKNQFTVPDNRNYIARNEARLKEFEARRAPLEKVTF
>NC_011369.1|WP_012556764.1|556694_559004_+|RNA-binding-transcriptional-accessory-protein
MAADLRFLAARISAEINARPEQAKAAIELLDEGATVPFIARYRKEVTGGLDDTQLRNLAERLVYLRELEARRAAIVESITGQGKMTDELMGKVAGAETKAELEDLYLPYKPKRRTRAEIARERGLGPLAETILADRGREPAALAEGFVTADVPDVKTALEGARDIIAEGIAENADLLGRLRAHMRQASLLKAKVVDGKQATGEKFSDYFDHSERWATAPGHRALAMLRGWNEEVLTLTIEADAETASPNKPVERMIAVAYEIGASRPGDRWLMEVASWTWRVKLSMSLSLDLMRELRERAEEEAIHVFARNLKDLLLAAPAGSRATMGLDPGIRTGVKVAVVDGTGKVVATSTVYPFQPRNDVRGAQIELASLIRKHNVELISIGNGTGSRETEKLVADMLAELPAPKPTKVIVSEAGASVYSASATAAAEFPDLDVSLRGAVSIARRLQDPLAELVKIEPKSIGVGQYQHDVDQQKLSRSLDAVVEDAVNAVGVDLNTASAPLLSRVSGLGPSIADAIVRHRDSEGRFETRRDLLKVARLGGRTFEQCAGFLRIPNGKEPLDASSVHPEAYGVAKKIVAACGRDLRALMGDSAMLKSVDPRQFIDEKFGLPTVRDIISELEKPGRDPRPSFKTAAFAEGVNEISDLKPGMMLEGTVTNVAAFGAFVDIGVHQDGLVHVSQLADRFVKDPHEVVKAGDVVKVRVVEVDAKRKRIALSMKRDDGSAAPPPRGDSRGNQGSRPQNERRPAAPKPESQGAFGAALAEAMKRK
>NC_011369.1|WP_012556763.1|554082_556266_-|glycine--tRNA-ligase-subunit-beta
MPNLLLELRSEEIPARMQRKAAGDLKKLVTDALVEAGLSYEGAREYWTPRRLALDIHGLTARSADVREERKGPRTDANEKAIEGFLRGAGLSSVSEAQVVSDPKKGDFYVAVISKPGRAAEEIVAEVMPGIIRDFPWPKSMRWGKASSRPGAMRWVRPLQSIVCTFGPEHEETVVIPFEIDGITASNTTYGHRFHAPEAITVRRFDDYAASLEKAKVILDAERRKDIILHDARDIAFANGLELVEDEGLLEEVSGLVEWPQVLMGSFEEDYLSIPSEIIRLTIKTNQKCFVTRKQGEETLSNKFILVSNIQAHDGGKEIVHGNGKVVRARLSDALHFWKRDQGDLPDLETLTASAAKFGLDLKKPLDQRMAKLDALDVTFHAKLGTQGARVARIRALAEELAKITGADAALTDRAAVLAKADLRTEAVGEFPELQGLMGRKYAGLQGENGSVAAAIEDHYKPQGPSDRVPADKVAITVALADKLDTLIGFWAIGEKPTGSKDPFALRRAALGVVRILLERNVRLPLLTIMSQTSLLAKTGGDTVFAFAGDPAETFFDLLSFFHDRLKVYLRDQGARHDLIDAVLTSDADDLLMVARRVEALTAFITSEDGKNLLAGTKRATQLLAAEEKKGTVIADAVSPALLKLDAEKELFAAISGASKEAADAVASEDFRSAMAALSKLRGPVDRFFEDVLVNDEDAAIRANRLALLRLIREATGTVADFSKISG
>NC_011369.1|WP_012556762.1|551893_553711_+|cache-domain-containing-protein
MKNLKISKQLILLVVGLMIAFAVATSLQIRSSVDAIYKERYDMLRAEVQSAVSVLKLYQAKVTAGEMTLEEAQKQAYATVNAMKYDPDGYFFGYSYDIQMMFHFDASKIGQVNKGQPDSKGKLYREELVRLGQQGGGLVEYYSTAKPGQPAGDFRKTAYAQAFDPWKVVVVTGVYMEDLDAQINSTILTALSGSIILFFLAIAAAYLVIRGISGPLNNVHAALKAVAEEDVSIAIPHAGMNNEVGMMAKATQSLQEKIRERHAMSDREAAQQLALENERENNQRQQQDETALQARVVATIGQALEMIARGDLTVRCADLGQKYAALRDNFNDALSHLEAAMAKVSAKGTDIGTSKEEIRRASNELSQRTERQAASLEETSAALDELTVAVRQTADGAHEASKRVHSVSNEATHSDAIVGQAIEAMSGIEKSSSEITKIIGVIDEIAFQTNLLALNAGVEAARAGESGKGFAVVAQEVRELAQRSAAAAKEIKDQIARSSSQVEHGVRLVGEAGEALKRISDQIKAANEIVAKIAHSASEQDTTLRSISSSMNQLDAATQQNAAMAEETTASAETLASDTDELIDLIRGFRVSAAAPALHQGRRAA
>NC_011369.1|WP_012556761.1|550999_551461_+|hypothetical-protein
MRQIFLGAAILLMAGSAMASSIEVIGKTAAPAEGSIVTESCAACPPLQAELIKKDYTVPELKPGVLQASEVRDVDGEKKIYRTEGWMGGSPVVFVSKATPETTIAAAPSAPSADGIDMSATTAAVIGGDAKPVVAGMAEQPAALNVSDFELRF
>NC_011369.1|WP_012556760.1|549622_550906_+|phosphoribosylamine--glycine-ligase
MKVLLIGSGGREHALAWKLAQSPLMTEFYAAPGNPGIAEHAMLVPVNIEDHEAVAAFCKDKAIDFVVVGPEAPLVAGLADRLRADGLVVFGPSAAAAQLEGSKGFTKDICARYGIPTGAYQRFNNAPKAKAYIRDQGVPIVVKADGLAAGKGVTVAMTLDEALAAVDDCFEGAFGAAGAEVVVEAYLDGEEASFFCLCDGKNALPLATAQDHKRVGEGDTGVNTGGMGAYSPAPVMTAEMVERTMKEIIEPTMRGMAESGHPFSGVFFAGLMITSRGPELIEYNVRFGDPECQVMMMRLKSDLLPLLLATANGTLDQMSAEWSDDPALTVVMASKGYPAAYEKNTPILSLPEAGEGEKVFHAGTGLKDGALVATGGRVLNVTASGGTVAEAKDRAYALLDRVKWDNGFSRRDIGWRAIERETGSDKV
>NC_011369.1|WP_012556759.1|547622_549557_+|DUF2207-domain-containing-protein
MGRRFFGFCLALLLMLAASAAFAAEVIDNFASAIQLEKSGAMTVAETITVNAEGNRINHGIFRDFPLYFTDAEGRRRSVDFDMVSVTRDGEDEPWHTESISGGIRIYAGSADVSVTPGRHRYVFTYKTNRQIRYFDDHDELYWNVTGNGWIFPIRSATATVTLPPGVTATETTFFTGPQGATGKNARVSETGAGLVFATTAPLDANEGLTFAVRMPKGSIDPPSADMESTWWLKDNRNYFIGFGGLILVFAYYLRSWLKVGRDPARGVVVPRWDAPDGISPALVNYIDNKGFSGGGWTALASTALNLAVRGYVKLEDLKNSIVIRGTGKPLGKEKFQAGEAELLRVAGGAGATLTIDKANGERVKSVGQSFRSAIEKEHRGKYYNSNIGYTTGGIALSAAALVALFVFGSLQPDTIALMLVPTAISVFVAVFVAGFMRSMHRGNSLFGKIVAIIATAVGVFVGISILAVVVLALASSLVQLHETPMLFAVGGIVLLNILYFFIMGAPTPLGARMMDGIDGLRQYLTLAEKDRMNTAGAPEMSPQHFETLLPYAVALGVEKPWSRAFETWLAAAAAGAAAAYAPTWYSGNFNSGSFSDRVGGFSSSMASTIASTIPSPPPSSSSSGFSGGGSSGGGGGGGGGGGW
>NC_011369.1|WP_012556758.1|546323_547586_+|3-phosphoshikimate-1-carboxyvinyltransferase
MTRTAKLTIIPPGKPLSGRAMPPGSKSITNRALLLAGLAKGTSRLTGALKSDDTRYMADALRAMGVSIDEPDDTTFVVTGSGRLQPPKAPLFLGNAGTATRFLTAAAALVDGTVVVDGDEHMRKRPIGPLVEAMRTLGIDVTAETGCPPVTVKGTGRFQADRIRIDGGLSSQYVSALLMMAAGGDRPFDIELVGEDIGALGYIDLTTAAMKAFGAKVEKTSPVTWRVEPTGYRAADFIVEPDASAATYLWAAEVLTGGAIDLGVPSDAFSQPDARAYDMIARFPQLPAEIDGSQMQDAVPTLAVLAAFNETPVRFVGIANLRVKECDRIRALSSGLNRIRPGLAREEGDDLIVKSDPALVGKRLPAEIDSFADHRIAMSFALAGLKIDGITILDPDCVGKTFPAYWRTLAALGVTYQDKD
>NC_011369.1|WP_012556767.1|562165_563125_+|4-hydroxybenzoate-octaprenyltransferase
MQDTGDFNDRVSDAPSDNWVYRILPPWLWPYAQLARWDRPIGWQLLMWPCFWSATLAANAAIGEGLYSGSLLVSHLVLYFIGAVAMRGAGCTYNDLVDHEIDMEVARTRSRPLPSGRVTRAHAKIFIGLQALVGLFVLLQFNWFTVFLGVLSLGIVALYPYAKRFTDWPQFYLGLAFSWGALMGWAGILGGLSFAAVLLYAASVAWTIGYDTIYAHQDKEDDELIGVRSTARLFGDRTRVWLIGLYGLTLVLMFAAFALAGANLIAFLALFGAAGMFAWQIVRLDINDAAQCLALFKSNNRVGLIIFFGLFVSLLFAIP
>NC_011369.1|WP_012556768.1|563206_563773_-|hypothetical-protein
MNNPVMKPAWAGTTLRLDPSRFPQQVSYAIHDCSDDVNITIDERGAVLRKVLPSSGLPLSIALPKRVFQGVAARAIDHGDGEVTVTLELHHADPELCIPLLVAHDLSDIAADWRGWSEAFRIPMLMVEADGVARPLEDHIGGLRTSDLKPRRRHSYFANRRPRFLVRRTTGRLGVAMKIEGKEIIARN
>NC_011369.1|WP_012556769.1|564070_567406_+|DUF1217-domain-containing-protein
MITASLAYTILSKDMTSSLNKVASQATVKKDAEYYADHINKVTSVDDFLGDYKLYSYAMKAYGLEDMTYAKAFMKKVLESDLTDPNSYANKLSDTRYREFASAFNFNAPEKDVQTDAQEDDLIGLYKQSFIDADKATTAESTYYSNNIDSVTTVDDLVNNTRLRTYVLKTFNIDPTYASKDFLRQVLTSDLSDPTSVVNTQGGDKYKALAAQFSFNADGTVTGTAQTAAQKASVIETYTLNSQSVIIDNSVGSDVVYVNKTAADYNQAYYTAKIGTITNVDDLVADKRLTSYIKTAYSMGADFTAAALRTVLTDPGYAQLMGFTNVYNAFNFKSDGSTSSTARVRTLDQANKLSSAASQTANYYKVTSQSSSITNVDALLADGNMARYIKDAYGLGTGFSNADLKNILTDSAYAAAQGHADLNADFNFQADGSINGSVIQTDTQRKSTTDKSAANAAHFNAMIDSVTSVDDIMSDPVAVSYLRTSMQVADSVSDATLRTFLVDPAAASAQGYSDVHDLFNFKTDGSVATLYASQTAAQSASTSSKADNAAVYYQATIAGIANVDQLLSDQKLNNFVRNAFGIPSTVTDVALRGILTDQSGTGTYADVAAAFNFKADGSLKDGLAAQTDTQIRNTKFAAGARTDDYSARMATIANVDDLIADPAITNFLKSTYNLPLNISNADLKSYLTDATAASAAGYADLNADFNFAADGSLPVVSSVQTADQAQTTNDNYMARYDDEREEAIDEVASNYSSMMADSTSLLDTAEIKSVNDFMRTNATADFKKSNDNLPDPYHVALQAFGLTEQDVPRSMMRKILTSDAYDPNGYIASLKDERITNMARAFNFGPDGKAASPFQALPDATLAKYATDYKAHMTMLLKAGPVKDKASKDATTEVDYFAKGMAKVKSLDDFLDDSRLTDLVLKANNLDPKDYDKATLKKIFTSDPDDKKSYLNAKADARFKDIVAAFNFDKDGNLTRAKMGTIQNKAAEEHTQELYVQQTMEAQQGESNDGVRLALYFSRKAPSITSIYSILGDKALYQVVTTAYSLPSQMSGMDVTKQADLLNRFVKLEDLQDPKKVDKLVRRFTAMYDVQNSTQQSPALQILTGGGTQSS
>NC_011369.1|WP_012556770.1|567586_569023_-|FAD-binding-oxidoreductase
MSSTGISTELLDRFAAIVGDKYALRGEADLAPHLVENRGLYHGSSPLLLKPGSVEEVSAIMKLATETGTAIVPQTGNTGLVGGQTPRAGQSDIILSLERMNRIRDVDPVANVLVADGGAILADVQKAAEAHGRLFPLSLGSEGSCRIGGNLSTNAGGTAVLAYGNMRQLCLGLEVVLPTGEIWDGLRRLKKDNTGYDLRDLFIGAEGTLGIITGAVLKLFPQPLGHQVAFAGLNSVADALGLFNLASSLCGTSLTGFELMPRFGVEITTRHIDGVRDPLQAAYPWYVLIDISTSDSAETAERMMNGVLEQGFAAGLVLDAAIASSVAQQQAIWHMRESMSDAQKPEGGSIKHDVSVPVSRIPHFMAEAADAVLAAMPGARICAFGHMGDGNIHYNISQPVGADKAAFIGRWREMNQIVHGLVLAHGGSISAEHGIGQLKRDELAAIRPAIEIELMRRIKRAFDPANIMNPGKVVSLEI
>NC_011369.1|WP_012556771.1|569059_570034_-|threonylcarbamoyl-AMP-synthase
MARIIDIEADRRAALEAASAALADGFAIAIPTETVYGLAADATNPAAITRIYETKGRPRFNPLICHMADLAMAEEHAEFDPVSRALAAAFWPGPLTLVLPLKPQSPIHSLATAGLDSVGVRVPKGFAGALIGAFGRPLAAPSANTSGAISATSAAHVEADLGAKVPLILDAGPSTVGVESTIVKVEGDRVRLLRPGGLAAREIERVAGRPLLRAKTASAAIEAPGMLASHYAPGAAVRLNATAVEPGEALIAFGGAAVSGTNGARIVLDLSPRGDLAEAAANLFDYMKRADASGASSIAFSAIPEEGLGEAINDRLQRAAAPRD
>NC_011369.1|WP_012556772.1|570122_570731_-|hypothetical-protein
MAKLRYFDAKDASRSQEPQLVAAHSEFLRTGRIPRERRHWLAEEKRYFTHDEVAAKTGRKLQVAGEKTHQHINGFHHSIQFPKMIFHRTLEDSPHLGYCHVTAARTKFAHYEEVSWAFYIANFYSDIGENDNFFERIDVGYSRMYFAVAIKAGENSQDKMTIDRSVRGNGLLFRTHDPQAAIRNILLLGARNEQLREIIRQL
>NC_011369.1|WP_012556773.1|571134_572379_+|aromatic-ring-hydroxylating-dioxygenase-subunit-alpha
MDIRSNVLRQLKNRREGFSLERPFYIDEDYFQLDMEMIYYRDWLFIGHDCELPKAGAYFTVQIGSYPVVIVRGKDNVIRAFHNSCRHRGSRVCTKEHGSSVRLVCPYHQWTYDLEGKLAFARHMGDDFDKTGFNLKPVHCEVVAGYVFICLADTAPNFQPVRDKIEPYVAPHRISESKVAFQSTIIEKGNWKLVWENNRECYHCAANHPELCRTYPEAPSVTGTDGGADDPEIAGHWARCEAAGLPSKFQISPDGQFRTARMPLIEDAESYTMSGRPAVKRSLADDISISHIGTMLLFHYPTTWNHLLGDHAISFRVLPLSANETAVTTKWLVHKDAVEGVDYNLEELTHVWTETNDQDRRIVEENAFGIHSPAYEPGPYSSLHEGGVMQFLEWYSNFMVNRLQGDQTKISAVA
>NC_011369.1|WP_012556774.1|572516_572987_+|BA14K-family-protein
MFGLSNKIATAVLAAAVVLTGFVPSQAIQMPTAPQVEKSSTVENVQYRRYYRGDYYRPGYRPGAYYRPGYYGGYRGYSYYRPGYRHYNGYWYPLAAFGAGAVIGGAIVAQPRYVAPAPRMGSSHVAWCANRYRSYRAYDNTFQPYNGPRQQCYSPY
>NC_011369.1|WP_003588177.1|573051_573315_-|DUF982-domain-containing-protein
MKWCTSEEFAPLMLVVSGPEKYKLVASLVQAAEMLTVGWPIDDGDEYLIAIRACRAAIHGEISAQDARAALIRAADEAGISVITAVH
>NC_011369.1|WP_012556775.1|573693_574839_-|IS4-family-transposase
MRHDNSVFHDVLKRIPWTAFERLVEEHQADKHVRRLSTKSQLIALLYGQLAGATSLREIVGSLQSHGTRLYHLGARPVSRSTFADANGLRPSAVFAELFAQMVARAGRGLKRAVGEAVYLIDGSSLSLAGAGSQWARFSDQACGAKMHVVYDANAERPIYAAVTPANVNDITAAKEMPIEAGATYVFDLGYYDFGWWAKLNAAGCRIVTRLKSHTRLTVSAEQAANADAGILFDRIGLLPQRQAKSRRNPMNRPVREIGVRIETGKVLRIFSNDLTAPAEEIAALYKRRWAIELFFRWVKQTLKIRHFLGNSENAVRIQVAVALIAYLLLQMAKADQATVTSPLAFARLVRTNLMHRKRIDRLLKPRHSPPGNPGQMSLQW

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Crispr_ID: NC_011369_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_011369_2

1525879-1525984

Orphan

Consensus_repeat	Method
AAAGCATGTCGCGCAAAAGTGTGC	CRISPRCasFinder

1 spacers

The CRISPR arrays of NC_011369_2

>merge|NC_011369|2|1525879-1525984|CRISPRCasFinder
AAAGCATGTCGCGCAAAAGTGTGCCGCGGTTTTCCCAGGCAAAGCGCGAAGCGCTTTTGCCGCAACGACATGCGCAAAAACCAAAGCATGTCGCGCAAAGGTGTGC

>NC_011369|2|2|1525879-1525984|CRISPRCasFinder
AAAGCATGTCGCGCAAAAGTGTGC	CGCGGTTTTCCCAGGCAAAGCGCGAAGCGCTTTTGCCGCAACGACATGCGCAAAAACC
AAAGCATGTCGCGCAAAGGTGTGC

Protein	Signature genes	Signature genes Name	Protein_function
NC_011369.1\|WP_012557491.1\|1530036_1530423_+\|membrane-protein	unknown	unknown	gnl\|CDD\|226260
NC_011369.1\|WP_003586937.1\|1533928_1534075_-\|DUF1127-domain-containing-protein	unknown	unknown	gnl\|CDD\|227744
NC_011369.1\|WP_003586945.1\|1522666_1523440_+\|5'/3'-nucleotidase-SurE	unknown	unknown	gnl\|CDD\|234732
NC_011369.1\|WP_012557482.1\|1516801_1517815_+\|beta-N-acetylhexosaminidase	unknown	unknown	gnl\|CDD\|224389
NC_011369.1\|WP_012557486.1\|1521378_1522662_+\|serine--tRNA-ligase	unknown	unknown	gnl\|CDD\|235461
NC_011369.1\|WP_003538990.1\|1519585_1519777_+\|twin-arginine-translocase-TatA/TatE-family-subunit	unknown	unknown	gnl\|CDD\|234822
NC_011369.1\|WP_012557492.1\|1531354_1531822_+\|hypothetical-protein	unknown	unknown	unknown
NC_011369.1\|WP_012557484.1\|1518687_1519404_+\|SMC-Scp-complex-subunit-ScpB	unknown	unknown	gnl\|CDD\|224304
NC_011369.1\|WP_003586940.1\|1530425_1531283_+\|phytoene/squalene-synthase-family-protein	unknown	unknown	gnl\|CDD\|224478
NC_011369.1\|WP_003539017.1\|1533484_1533628_-\|DUF1127-domain-containing-protein	unknown	unknown	gnl\|CDD\|227744
NC_011369.1\|WP_012557493.1\|1531943_1533377_-\|methylenetetrahydrofolate--tRNA-(uracil(54)--C(5))-methyltransferase-(FADH(2)-oxidizing)-TrmFO	unknown	unknown	gnl\|CDD\|235416
NC_011369.1\|WP_012557487.1\|1523436_1524090_+\|protein-L-isoaspartate(D-aspartate)-O-methyltransferase	unknown	unknown	gnl\|CDD\|178974
NC_011369.1\|WP_012557483.1\|1517833_1518691_+\|segregation/condensation-protein-A	unknown	unknown	gnl\|CDD\|224273
NC_011369.1\|WP_003586948.1\|1520451_1521279_+\|twin-arginine-translocase-subunit-TatC	unknown	unknown	gnl\|CDD\|223876
NC_011369.1\|WP_012557490.1\|1527491_1530032_+\|protein-translocase-subunit-SecDF	unknown	unknown	gnl\|CDD\|237805
NC_011369.1\|WP_012557485.1\|1519828_1520455_+\|twin-arginine-translocase-subunit-TatB	unknown	unknown	gnl\|CDD\|234818
NC_011369.1\|WP_012557489.1\|1526022_1526895_-\|ATP-binding-protein	unknown	unknown	gnl\|CDD\|225327
NC_011369.1\|WP_003573534.1\|1527098_1527446_+\|preprotein-translocase-subunit-YajC	unknown	unknown	gnl\|CDD\|224775
NC_011369.1\|WP_012557494.1\|1534946_1536050_+\|DUF2157-domain-containing-protein	unknown	unknown	gnl\|CDD\|227209
NC_011369.1\|WP_012557488.1\|1524229_1525822_+\|peptidoglycan-DD-metalloendopeptidase-family-protein	unknown	unknown	gnl\|CDD\|223810

Protein	Function_ID	Function_description	E-value
NC_011369.1\|WP_012557491.1\|1530036_1530423_+\|membrane-protein	gnl\|CDD\|226260	COG3737, COG3737, Uncharacterized conserved protein [Function unknown].	4.39785e-60
NC_011369.1\|WP_003586937.1\|1533928_1534075_-\|DUF1127-domain-containing-protein	gnl\|CDD\|227744	COG5457, COG5457, Uncharacterized conserved small protein [Function unknown].	8.6446e-09
NC_011369.1\|WP_003586945.1\|1522666_1523440_+\|5'/3'-nucleotidase-SurE	gnl\|CDD\|234732	PRK00346, surE, 5'(3')-nucleotidase/polyphosphatase; Provisional.	1.02422e-125
NC_011369.1\|WP_012557482.1\|1516801_1517815_+\|beta-N-acetylhexosaminidase	gnl\|CDD\|224389	COG1472, BglX, Beta-glucosidase-related glycosidases [Carbohydrate transport and metabolism].	2.23783e-96
NC_011369.1\|WP_012557486.1\|1521378_1522662_+\|serine--tRNA-ligase	gnl\|CDD\|235461	PRK05431, PRK05431, seryl-tRNA synthetase; Provisional.	0
NC_011369.1\|WP_003538990.1\|1519585_1519777_+\|twin-arginine-translocase-TatA/TatE-family-subunit	gnl\|CDD\|234822	PRK00720, tatA, twin-arginine translocase TatA/TatE family subunit.	6.67623e-37
NC_011369.1\|WP_012557484.1\|1518687_1519404_+\|SMC-Scp-complex-subunit-ScpB	gnl\|CDD\|224304	COG1386, scpB, Chromosome segregation and condensation protein B [DNA replication, recombination and repair].	1.66185e-60
NC_011369.1\|WP_003586940.1\|1530425_1531283_+\|phytoene/squalene-synthase-family-protein	gnl\|CDD\|224478	COG1562, ERG9, Phytoene/squalene synthetase [Lipid metabolism].	7.74224e-59
NC_011369.1\|WP_003539017.1\|1533484_1533628_-\|DUF1127-domain-containing-protein	gnl\|CDD\|227744	COG5457, COG5457, Uncharacterized conserved small protein [Function unknown].	1.01998e-10
NC_011369.1\|WP_012557493.1\|1531943_1533377_-\|methylenetetrahydrofolate--tRNA-(uracil(54)--C(5))-methyltransferase-(FADH(2)-oxidizing)-TrmFO	gnl\|CDD\|235416	PRK05335, PRK05335, tRNA (uracil-5-)-methyltransferase Gid; Reviewed.	0
NC_011369.1\|WP_012557487.1\|1523436_1524090_+\|protein-L-isoaspartate(D-aspartate)-O-methyltransferase	gnl\|CDD\|178974	PRK00312, pcm, protein-L-isoaspartate(D-aspartate) O-methyltransferase.	5.08917e-107
NC_011369.1\|WP_012557483.1\|1517833_1518691_+\|segregation/condensation-protein-A	gnl\|CDD\|224273	COG1354, scpA, Rec8/ScpA/Scc1-like protein (kleisin family) [Replication, recombination, and repair].	5.24222e-69
NC_011369.1\|WP_003586948.1\|1520451_1521279_+\|twin-arginine-translocase-subunit-TatC	gnl\|CDD\|223876	COG0805, TatC, Sec-independent protein secretion pathway component TatC [Intracellular trafficking and secretion].	2.37819e-94
NC_011369.1\|WP_012557490.1\|1527491_1530032_+\|protein-translocase-subunit-SecDF	gnl\|CDD\|237805	PRK14726, PRK14726, protein translocase subunit SecDF.	0
NC_011369.1\|WP_012557485.1\|1519828_1520455_+\|twin-arginine-translocase-subunit-TatB	gnl\|CDD\|234818	PRK00708, PRK00708, twin-arginine translocase subunit TatB.	3.04414e-81
NC_011369.1\|WP_012557489.1\|1526022_1526895_-\|ATP-binding-protein	gnl\|CDD\|225327	COG2607, COG2607, Predicted ATPase (AAA+ superfamily) [General function prediction only].	4.41913e-161
NC_011369.1\|WP_003573534.1\|1527098_1527446_+\|preprotein-translocase-subunit-YajC	gnl\|CDD\|224775	COG1862, YajC, Preprotein translocase subunit YajC [Intracellular trafficking and secretion].	2.17356e-32
NC_011369.1\|WP_012557494.1\|1534946_1536050_+\|DUF2157-domain-containing-protein	gnl\|CDD\|227209	COG4872, COG4872, Predicted membrane protein [Function unknown].	2.23867e-43
NC_011369.1\|WP_012557488.1\|1524229_1525822_+\|peptidoglycan-DD-metalloendopeptidase-family-protein	gnl\|CDD\|223810	COG0739, NlpD, Membrane proteins related to metalloendopeptidases [Cell envelope biogenesis, outer membrane].	1.35336e-37

>NC_011369.1|WP_012557488.1|1524229_1525822_+|peptidoglycan-DD-metalloendopeptidase-family-protein
MRFSLSPKFGKSAGNLLVVSLLASAATGCSSDVTRFGGLFSSSGQDQITTSSIPRRGGAQADPVPRADLGGSAVASQSGYGGGNGALNQPYPSNPSYDPVRTSSARMASAPVAVQRSELAAPGAVAPVRQREKEVALAQPFPSAPQAEKNRLVAPTAPKLTPDTLTTGTTPKVSGWSGTNAPSVTLRPGESVATLSRRFGVPEKEILRVNNLKTASAATPGQAILIPTFNGGNAAKAASQAADLSKPGKMPEPVKAPEQNVAVVPGANSARDKTMASADATGKLPPGAGKDPKAPAGTYVVKQGDSLAKIAKATGTKIDDLKAANNLSASSVRVGQALKIPSGTADNIKTASIQPQKVDPKPAQTAPAQQTASVEPAPYKAPVATQTVDDVEKKSDVSSAAPESTGIGKYRWPVRGQVIASYGANVNGNRNDGIDISVPQGTPIKAAENGVVIYAGNGLKELGNTVLVRHDDGTVTVYGNADTLSVARGQKIQRGQTVAVSGMSGDVKQPQVHFEVRKDASPVNPMTFLE
>NC_011369.1|WP_012557487.1|1523436_1524090_+|protein-L-isoaspartate(D-aspartate)-O-methyltransferase
MTARLAEKEGFAALVLRLRAEGISDLDLLTAVEQTQRSLFVPPQFYDDAYSSRTIPIECGSFLEGIDFVVRILHHLKLKPGQRVLEIGTGSGFTAAVMGRMAERVLSIDRYKTLTSAAQRRMESLSLRNVIIRHADGSAGMQGEGTFDRILVTAAFNAMPRFYTDQLVSGGSMIAPLMISENECRMVRLTKTGSRFEREELFEAPYLPIVPRLAALL
>NC_011369.1|WP_003586945.1|1522666_1523440_+|5'/3'-nucleotidase-SurE
MRILLTNDDGIHAEGLAALERIARTLSDDVWIVAPETDQSGLAHSLSLSEPLRLRKISDKHFALRGTPTDCVIMGIRQVMDIKPDLVLSGVNSGSNVADDVTYSGTIAGAIEGTMQGVRSFALSQAYLYEDGARIVPWEVCETHAPALLEKLMVLDLPEGTFLNLNFPNCRPGEVDGAEVTMQGKLAFNLQVDARSDGRGFPYYWLKFGERAGAFIEGTDIHALKHNKISVTPLKLDLTDYSVTDRVARALGYGAQV
>NC_011369.1|WP_012557486.1|1521378_1522662_+|serine--tRNA-ligase
MLDIKWIRENPEALDAALAKRGAEPLAQNLVALDEKRRSAVQKAQDLLSRRNLASKEIGAALSQKNGELAEKLKVEVAELKAMLPAVEEEDRQLTAELNDALSRIPNIPFDDVPVGKDEHDNVVTRTVGEKPRWNHTPKEHFEIGEALGYMDFERAAKLSGSRFTVLTGPLARLERALGQFMIDLHTREHGYTEVSSPLMVRAEALFGTGNLPKFEEDLFKTTDGRYLIPTAEVTLTNLVREEILDQEKLPLRFTALTPSFRSEAGSAGRDTRGMLRQHQFWKCELVSITDAESAVAEHERMTACAEDVLKRLGLHFRTMTLCTGDMGFGSRKTYDLEVWLPGQNAFREISSCSVCGDFQARRMNARYRGKDDKSNRFVHTLNGSGTAVGRCLIAVLENYLNEDGSVTIPDVLLPYMGGLTKIERAA
>NC_011369.1|WP_003586948.1|1520451_1521279_+|twin-arginine-translocase-subunit-TatC
MSGDIEDKPQPLIEHLMELRTRLIWSIGAFFVAFIACFFFAKHLFNYLVIPYKTAVQWAHLDVEKAQLIYTAPQEFFFTQVKVAMFGGLVVAFPIIAAQVYKFVAPGLYKNERQAFLPFLIASPVLFLMGAALVYFFFTPMVMWFFLSMQQAPGHDEVAISLMPKVSEYLSLIMTLVFSFGLVFQLPVITTLLARVGLLTSQWLAEKRKFAIVLAFIVAAVLTPPDPMSQIGLAIPTILLYEISIHAARLVERQRARQAVEKDTESADVAKTDSV
>NC_011369.1|WP_012557485.1|1519828_1520455_+|twin-arginine-translocase-subunit-TatB
MFDIGWTELLVIAVVLIVVVGPKDLPPMLRAFGKMTQRARKVAGEFRAQFDEALREAELDDVRQTLSDAQKLNPVNSLREAMNPLRQMGNEIKADLQKATAVPENKTEVPPAAVSAPTPSMGLPETPPLVPAPAPTPEPVAAAVATADTVAAKSKAVRKLRAKAADKAAFAIAAPVENVPAEKPKRTTAARKPAAPKTPAQMKKKDEA
>NC_011369.1|WP_003538990.1|1519585_1519777_+|twin-arginine-translocase-TatA/TatE-family-subunit
MGSFSMWHWLIVLVIVLLLFGRGKIPELMGDVAKGIKSFKKGMTDEDAPDTAKTVDHKADETK
>NC_011369.1|WP_012557484.1|1518687_1519404_+|SMC-Scp-complex-subunit-ScpB
MIDPKSDEDFEDDFEGRSRDLQAEIEAERIAEALVFASSQPVSEGFLAERLPEKTDVRAIMLRLKAHYAPRGVNLVQIEGAWAFRTAADLSVVIRRDDNEVKKLSRAALEVLAIIAYHQPVTRAEIEDIRGVQTSRGTLDVLMEAGWVRFRGRRRTPGRPVTLGTTRDFLDHFGLEELRDLPGLEELKGAGLLSGRIPANFNIPSPLMNDELTEDEDPITQMDLEELGLLAPRGTSED
>NC_011369.1|WP_012557483.1|1517833_1518691_+|segregation/condensation-protein-A
MITVKGTERPQAATPMDKLWQENGAERASHEPALVIDVAGFEGPLDLLLYLARNQKVDLSRISVLALAEQYLQFVESARRIRIELAADYLVMAAWLAYLKSRLLIPQQIKDDGPSGEEMAATLAFRLKRLEAMRQAAEGLVNRNRLGRDIFVRGAPEHIPDRQQSAYAASLYDLLTAYAALRQRNAVTQVTIERRNVWSLTDARELLTQMIGEVGDWTAMEHYLLRYLATPEERVTAIASAFAASLELVREGKLEIRQDGAFQPIYMRRGPKYATLQVVEQEQPA
>NC_011369.1|WP_012557482.1|1516801_1517815_+|beta-N-acetylhexosaminidase
MTESKAMILGCSGLALTSEEKAFYRGERPWGFILFGRNISEAGQIADLVAELRDSVGWHAPVLIDQEGGRVQRIRPPVFARYPSGQALGDLYRRDPALGLRAAWVMSRLHAFDLSSLGIDVDCLPVLDVPVEGSSSVIGDRAYGGDPQTVIAMGRAAAEGLKAGGLLPVMKHMPGHGRGFADSHLELPVVTVSRDELEAHDFPPFIAMKDELMAMTCHVVFTAIDPDNPATTSRKVIDGVIREQIGFTGLLLSDDSSMNALSGTIGERAANIIAGGCDIVLHCNGHMDEMQDVVANVPPLAGQSLARAKAVEAGFAAPDAADEAELRAEFEAMFAIV
>NC_011369.1|WP_012557489.1|1526022_1526895_-|ATP-binding-protein
MTEEINTALLAELKRLANAVERLAGPAPAANDWDAADCFVWAPSRLHLQPVNKPNRVALKLIRGVDHVRDILHENTVRFAEGYAANNVLLWGARGMGKSSLVKAVHEDVRRESGAALKLVEVHREDIASLPNLLDLLKDTPYRVIVFCDDLSFDHDDTAYKSLKAALDGGVEGRPDNVLFYATSNRRHLLPRHMMENEQSTAINPSEAVEEKVSLSDRFGLWLGFHKCSQEDYLGMIDGYAEHFKLGLERDKMHAEALEWATTRGARSGRVAWQYIQDLAGRMRIHIDRA
>NC_011369.1|WP_003573534.1|1527098_1527446_+|preprotein-translocase-subunit-YajC
MFITPAFAQSATDTATGFGGSGFEMIILFVPLMVVWYFLLIRPQRAQAKKREETLKAIRRGDQVVTGGGLVGKVTKVIDDKEVEVEIADGVRVRIVRSGISDVRVKGEPVKADAA
>NC_011369.1|WP_012557490.1|1527491_1530032_+|protein-translocase-subunit-SecDF
MLHFSRWKTLLIWLAAFAAIIIAAPNLLSEAQRSSLPGWLRQDRVTLGLDLQGGSHIVLKVERSDIVKDRLEEAVANVRNTLRGAGIRYTGLTGNDQTVTVRITDPAETQKAVELLKPLTTAGGRSGPEVALQQGEEGQLSLQISDAGITADVASARTRSLDIVARRIAGFGHANFIVRPDGTDRIVVQVLGSVDAERLKNLLNQPAKLSFHLIDASMSGQEALNGRWPATSQVLYSLDDPPVPYLVDRTAFLTGSNMVGIEPVVDPQTQDSSIAYRLDADGTRRLAEVTGQNIGKHLAIVFDDQVMSSPAIDAAITGGEGAISANFSEDGVRDLAIMLRAGALPATLTSVEERSVSPRFGADSIFSGLIAGLVAVVLVAALMIALYRILGVIAVVSLVFNLIFIVAALSLAGATLTLPGIAGIVLIVGMAVDSNVLIYERIREEEKTAHSFAEAAGRGFSRAFATIVDANVTIFIAAIILFFLGSESIRGFAVTLAVGILTTVFTAFTLTRSIVAVWLQRRHPRHLPKSVLTHLFEHANIRFMGIRRYVFTASAIISLIAMAAFATAGLRLGIDFTGGSLIEVTAKQGNADLADLQSRLNDLNLGEVSVTRAGGPSNARIRIASQGGGENAEQSAATLVRGELQEDYDFRRVEVVGPAISGELTMMATLGVLAALAAILIYIWVRFEWQFAVGAIVATLHDVIILLGLFVLTGMEFNLTSVAAVLTVVGYSLNDTVVVYDRMRENLKRYKKMPLPILIDASINQTLSRTILTAATTLLALLALYLFGGEVIRSFTFTMLFGVALGTFSSIYIAAPVLIVFRLRPESPDGEESNKTDAGVKSGTVV
>NC_011369.1|WP_012557491.1|1530036_1530423_+|membrane-protein
MAKGIEIRAAHFPGRAPIDTYGNGGFRFADMSHRGSILCLPSGIHGWDMDMSKPLSPENFRRVLDEADDIEVLLVGTGTELRRLPEALKQALKARGIASDPMSTGAAVRTFNIMLAEQRAVAAALIAV
>NC_011369.1|WP_003586940.1|1530425_1531283_+|phytoene/squalene-synthase-family-protein
MVEAKPATNQETCLAMLRDSDRDRYLACLLSPEDKRGALAALYAFNAELARIRDLVHEPLPGEVRLQYWRDLLEGSAHGSTAANPVASALLTAIETHRLPRKTLIDMIEARTFDLYDDPMETRLSLEGYAGETASALIQLASLVLSPEEAARSADAAGHAGVAQAVAGLLLLMPLYRRRGQVYIPLQILSATGLNRDTFLAGEDRQRISAAIEAFAGLGREHLAKARAAGPIAPAVFPAFLPATLAEPVLFRAQKLGAVLFDRPLQPPQWRRQLSMALSAVRRKI
>NC_011369.1|WP_012557492.1|1531354_1531822_+|hypothetical-protein
MGIIVWCVLFAIVIFFAFVVTRMAAQNKEDGLHDTGLAIIEFGRAFPNEAIRQLQATENGQAIFVRLHDNKAGFMRNMSRHFACHLIEPGRVRVVSSQTGRGLVIDFLDAPHHNGDFEFASAKESAEVALWLLGNYIAEPDKDLPSDHISAANKH
>NC_011369.1|WP_012557493.1|1531943_1533377_-|methylenetetrahydrofolate--tRNA-(uracil(54)--C(5))-methyltransferase-(FADH(2)-oxidizing)-TrmFO
MNTISSYSPIHVVGGGLAGSEAAWQIASSGVPVILHEMRGVRGTDAHKTDGLAELVCSNSFRSDDATSNAVGVIHAEMRMAGSLIMATADRHQVPAGGALAVDRDGFSEAVTRAIHDHPLITVVREEITGLPPGDWDLAIVATGPLTAPSLASAIQAQTGEDSLAFFDAIAPIVYRESIDMDICWYQSRYDKVGPGGTGKDYINCPMDEAQYNAFVDALISGDTVGFKEWEGTPYFDGCLPIEVMAERGRETLRHGPMKPMGLTNAHNPTVKAYAVVQLRQDNALGTLYNMVGFQTKLKYGAQAEIFRMIPGLENAEFARLGGLHRNTYINSPTLLDPSLTLKSRPGLRFAGQITGCEGYVESASVGLMAGRFAAAERKGEAISLPPATTALGSLLGHITGGHIVTDEEPGKRSFQPMNINFGLFPELQPGSIVKPEGVKRFRGKDKTIMKRQLIARRALADCAAWLGQNSPLAESA
>NC_011369.1|WP_003539017.1|1533484_1533628_-|DUF1127-domain-containing-protein
MNPIRIARSWLSYRRTLNELGGLSNQTLSDIGVSRYDIRNIASRSFR
>NC_011369.1|WP_003586937.1|1533928_1534075_-|DUF1127-domain-containing-protein
MNFSRSFNNWRKYRQTVTELGRMSNRELHDLGIDRSDIHRVAREASAR
>NC_011369.1|WP_012557494.1|1534946_1536050_+|DUF2157-domain-containing-protein
MYRGRLERDLSLWVGKGLLGQETAGALLAEYDSRPASFSLGRVLMALAAVLLAAAILLVVASNWEAIPRLIRVGVILALIWVVHLAAARMLARGASAAASGLLIIGAMSFGGAISLVGQMYHLSGDEQTVMYLWFAIATISAILFRSGAVAVVAGFLSWASFAVYLENYDTHWIGFDPWMAPVMAAIVIGLVRYTGAERARHLAYLLLIGWLAWLYTLYEEIAVALAFAIGGMAAFVLTALPTRSVASLVRSAGAAPAFYSFLVAAIGFLLLHIEIEDGWPLVVLGVATLAASVLAIALHGRDNGAVRYLAYTTFAAEMLYLASVTVGSILGTSSLFLFSGLVVALVAWIVIRLERRFSANAQGERA

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Crispr_ID: NC_011369_3

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_011369_3

1538408-1538493

Orphan

Consensus_repeat	Method
GCCGCCCCGAAGAAGAAGGCCGC	CRISPRCasFinder

1 spacers

The CRISPR arrays of NC_011369_3

>merge|NC_011369|3|1538408-1538493|CRISPRCasFinder
GCCGCCCCGAAGAAGAAGGCCGCCGCCAAGGCTGAAGCTGCCGACGCCGGCGAAGGCGAAGAAGCCGCCGCTCCGAAGAAGAAGGC

>NC_011369|3|3|1538408-1538493|CRISPRCasFinder
GCCGCCCCGAAGAAGAAGGCCGC	CGCCAAGGCTGAAGCTGCCGACGCCGGCGAAGGCGAAGAA
GCCGCCGCTCCGAAGAAGAAGGC

Protein	Signature genes	Signature genes Name	Protein_function
NC_011369.1\|WP_003586937.1\|1533928_1534075_-\|DUF1127-domain-containing-protein	unknown	unknown	gnl\|CDD\|227744
NC_011369.1\|WP_012557501.1\|1543625_1544453_-\|DNA-repair-protein-RadC	unknown	unknown	gnl\|CDD\|178801
NC_011369.1\|WP_012557499.1\|1541110_1541914_-\|endonuclease/exonuclease/phosphatase-family-protein	unknown	unknown	gnl\|CDD\|197317
NC_011369.1\|WP_012557498.1\|1539178_1540954_-\|radical-SAM-protein	unknown	unknown	gnl\|CDD\|214792
NC_011369.1\|WP_012557492.1\|1531354_1531822_+\|hypothetical-protein	unknown	unknown	unknown
NC_011369.1\|WP_012557502.1\|1544460_1545297_-\|type-I-methionyl-aminopeptidase	unknown	unknown	gnl\|CDD\|235576
NC_011369.1\|WP_012557503.1\|1545443_1546082_-\|zeta-toxin-family-protein	unknown	unknown	gnl\|CDD\|226648
NC_011369.1\|WP_012557497.1\|1538688_1539126_+\|nuclear-transport-factor-2-family-protein	unknown	unknown	gnl\|CDD\|226158
NC_011369.1\|WP_003586940.1\|1530425_1531283_+\|phytoene/squalene-synthase-family-protein	unknown	unknown	gnl\|CDD\|224478
NC_011369.1\|WP_012557504.1\|1546485_1547145_+\|TetR/AcrR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|224228
NC_011369.1\|WP_012557493.1\|1531943_1533377_-\|methylenetetrahydrofolate--tRNA-(uracil(54)--C(5))-methyltransferase-(FADH(2)-oxidizing)-TrmFO	unknown	unknown	gnl\|CDD\|235416
NC_011369.1\|WP_003586920.1\|1546092_1546269_-\|hypothetical-protein	unknown	unknown	unknown
NC_011369.1\|WP_148221745.1\|1543485_1543602_-\|DNA-repair-protein-RadC	unknown	unknown	gnl\|CDD\|178801
NC_011369.1\|WP_012557490.1\|1527491_1530032_+\|protein-translocase-subunit-SecDF	unknown	unknown	gnl\|CDD\|237805
NC_011369.1\|WP_041671708.1\|1541978_1543385_-\|Si-specific-NAD(P)(+)-transhydrogenase	unknown	unknown	gnl\|CDD\|235373
NC_011369.1\|WP_012557491.1\|1530036_1530423_+\|membrane-protein	unknown	unknown	gnl\|CDD\|226260
NC_011369.1\|WP_003573534.1\|1527098_1527446_+\|preprotein-translocase-subunit-YajC	unknown	unknown	gnl\|CDD\|224775
NC_011369.1\|WP_003539017.1\|1533484_1533628_-\|DUF1127-domain-containing-protein	unknown	unknown	gnl\|CDD\|227744
NC_011369.1\|WP_012557494.1\|1534946_1536050_+\|DUF2157-domain-containing-protein	unknown	unknown	gnl\|CDD\|227209
NC_011369.1\|WP_012557495.1\|1536046_1536637_+\|GDYXXLXY-domain-containing-protein	unknown	unknown	gnl\|CDD\|379571

Protein	Function_ID	Function_description	E-value
NC_011369.1\|WP_003586937.1\|1533928_1534075_-\|DUF1127-domain-containing-protein	gnl\|CDD\|227744	COG5457, COG5457, Uncharacterized conserved small protein [Function unknown].	8.6446e-09
NC_011369.1\|WP_012557501.1\|1543625_1544453_-\|DNA-repair-protein-RadC	gnl\|CDD\|178801	PRK00024, PRK00024, DNA repair protein RadC.	7.12953e-108
NC_011369.1\|WP_012557499.1\|1541110_1541914_-\|endonuclease/exonuclease/phosphatase-family-protein	gnl\|CDD\|197317	cd09083, EEP-1, Exonuclease-Endonuclease-Phosphatase domain; uncharacterized family 1. This family of uncharacterized proteins belongs to a superfamily that includes the catalytic domain (exonuclease/endonuclease/phosphatase, EEP, domain) of a diverse set of proteins including the ExoIII family of apurinic/apyrimidinic (AP) endonucleases, inositol polyphosphate 5-phosphatases (INPP5), neutral sphingomyelinases (nSMases), deadenylases (such as the vertebrate circadian-clock regulated nocturnin), bacterial cytolethal distending toxin B (CdtB), deoxyribonuclease 1 (DNase1), the endonuclease domain of the non-LTR retrotransposon LINE-1, and related domains. These diverse enzymes share a common catalytic mechanism of cleaving phosphodiester bonds. Their substrates range from nucleic acids to phospholipids and perhaps, proteins.	1.80497e-13
NC_011369.1\|WP_012557498.1\|1539178_1540954_-\|radical-SAM-protein	gnl\|CDD\|214792	smart00729, Elp3, Elongator protein 3, MiaB family, Radical SAM. This superfamily contains MoaA, NifB, PqqE, coproporphyrinogen III oxidase, biotin synthase and MiaB families, and includes a representative in the eukaryotic elongator subunit, Elp-3. Some members of the family are methyltransferases.	1.35164e-20
NC_011369.1\|WP_012557502.1\|1544460_1545297_-\|type-I-methionyl-aminopeptidase	gnl\|CDD\|235576	PRK05716, PRK05716, methionine aminopeptidase; Validated.	3.51487e-160
NC_011369.1\|WP_012557503.1\|1545443_1546082_-\|zeta-toxin-family-protein	gnl\|CDD\|226648	COG4185, COG4185, Uncharacterized protein conserved in bacteria [Function unknown].	3.22605e-45
NC_011369.1\|WP_012557497.1\|1538688_1539126_+\|nuclear-transport-factor-2-family-protein	gnl\|CDD\|226158	COG3631, COG3631, Ketosteroid isomerase-related protein [General function prediction only].	1.02094e-09
NC_011369.1\|WP_003586940.1\|1530425_1531283_+\|phytoene/squalene-synthase-family-protein	gnl\|CDD\|224478	COG1562, ERG9, Phytoene/squalene synthetase [Lipid metabolism].	7.74224e-59
NC_011369.1\|WP_012557504.1\|1546485_1547145_+\|TetR/AcrR-family-transcriptional-regulator	gnl\|CDD\|224228	COG1309, AcrR, Transcriptional regulator [Transcription].	2.43425e-08
NC_011369.1\|WP_012557493.1\|1531943_1533377_-\|methylenetetrahydrofolate--tRNA-(uracil(54)--C(5))-methyltransferase-(FADH(2)-oxidizing)-TrmFO	gnl\|CDD\|235416	PRK05335, PRK05335, tRNA (uracil-5-)-methyltransferase Gid; Reviewed.	0
NC_011369.1\|WP_148221745.1\|1543485_1543602_-\|DNA-repair-protein-RadC	gnl\|CDD\|178801	PRK00024, PRK00024, DNA repair protein RadC.	0.000664802
NC_011369.1\|WP_012557490.1\|1527491_1530032_+\|protein-translocase-subunit-SecDF	gnl\|CDD\|237805	PRK14726, PRK14726, protein translocase subunit SecDF.	0
NC_011369.1\|WP_041671708.1\|1541978_1543385_-\|Si-specific-NAD(P)(+)-transhydrogenase	gnl\|CDD\|235373	PRK05249, PRK05249, Si-specific NAD(P)(+) transhydrogenase.	0
NC_011369.1\|WP_012557491.1\|1530036_1530423_+\|membrane-protein	gnl\|CDD\|226260	COG3737, COG3737, Uncharacterized conserved protein [Function unknown].	4.39785e-60
NC_011369.1\|WP_003573534.1\|1527098_1527446_+\|preprotein-translocase-subunit-YajC	gnl\|CDD\|224775	COG1862, YajC, Preprotein translocase subunit YajC [Intracellular trafficking and secretion].	2.17356e-32
NC_011369.1\|WP_003539017.1\|1533484_1533628_-\|DUF1127-domain-containing-protein	gnl\|CDD\|227744	COG5457, COG5457, Uncharacterized conserved small protein [Function unknown].	1.01998e-10
NC_011369.1\|WP_012557494.1\|1534946_1536050_+\|DUF2157-domain-containing-protein	gnl\|CDD\|227209	COG4872, COG4872, Predicted membrane protein [Function unknown].	2.23867e-43
NC_011369.1\|WP_012557495.1\|1536046_1536637_+\|GDYXXLXY-domain-containing-protein	gnl\|CDD\|379571	pfam14345, GDYXXLXY, GDYXXLXY protein. This family of proteins is functionally uncharacterized. This family of proteins is found in bacteria, archaea and eukaryotes. Proteins in this family are typically between 171 and 199 amino acids in length. It contains a conserved GDYXXLXY motif.	8.88169e-43

>NC_011369.1|WP_012557495.1|1536046_1536637_+|GDYXXLXY-domain-containing-protein
MNSLMARLHSGRGYLLSAIIVAGLQTVILGTIIQSRASILNNGAEVLLKTAPVDPRDFLRGDYVVLNYDISSVPVQTVSGGIPAEPGERTLWVRLKKQEDGFWTVIESSFRELPPLPETVILRSQPFYSGGLAAGDSIRVEYGIERYYVPEGQGKPIEEARNGGNVAIAVRVSPAGSAQIRGLLVDGKPVYDEPLY
>NC_011369.1|WP_012557494.1|1534946_1536050_+|DUF2157-domain-containing-protein
MYRGRLERDLSLWVGKGLLGQETAGALLAEYDSRPASFSLGRVLMALAAVLLAAAILLVVASNWEAIPRLIRVGVILALIWVVHLAAARMLARGASAAASGLLIIGAMSFGGAISLVGQMYHLSGDEQTVMYLWFAIATISAILFRSGAVAVVAGFLSWASFAVYLENYDTHWIGFDPWMAPVMAAIVIGLVRYTGAERARHLAYLLLIGWLAWLYTLYEEIAVALAFAIGGMAAFVLTALPTRSVASLVRSAGAAPAFYSFLVAAIGFLLLHIEIEDGWPLVVLGVATLAASVLAIALHGRDNGAVRYLAYTTFAAEMLYLASVTVGSILGTSSLFLFSGLVVALVAWIVIRLERRFSANAQGERA
>NC_011369.1|WP_003586937.1|1533928_1534075_-|DUF1127-domain-containing-protein
MNFSRSFNNWRKYRQTVTELGRMSNRELHDLGIDRSDIHRVAREASAR
>NC_011369.1|WP_003539017.1|1533484_1533628_-|DUF1127-domain-containing-protein
MNPIRIARSWLSYRRTLNELGGLSNQTLSDIGVSRYDIRNIASRSFR
>NC_011369.1|WP_012557493.1|1531943_1533377_-|methylenetetrahydrofolate--tRNA-(uracil(54)--C(5))-methyltransferase-(FADH(2)-oxidizing)-TrmFO
MNTISSYSPIHVVGGGLAGSEAAWQIASSGVPVILHEMRGVRGTDAHKTDGLAELVCSNSFRSDDATSNAVGVIHAEMRMAGSLIMATADRHQVPAGGALAVDRDGFSEAVTRAIHDHPLITVVREEITGLPPGDWDLAIVATGPLTAPSLASAIQAQTGEDSLAFFDAIAPIVYRESIDMDICWYQSRYDKVGPGGTGKDYINCPMDEAQYNAFVDALISGDTVGFKEWEGTPYFDGCLPIEVMAERGRETLRHGPMKPMGLTNAHNPTVKAYAVVQLRQDNALGTLYNMVGFQTKLKYGAQAEIFRMIPGLENAEFARLGGLHRNTYINSPTLLDPSLTLKSRPGLRFAGQITGCEGYVESASVGLMAGRFAAAERKGEAISLPPATTALGSLLGHITGGHIVTDEEPGKRSFQPMNINFGLFPELQPGSIVKPEGVKRFRGKDKTIMKRQLIARRALADCAAWLGQNSPLAESA
>NC_011369.1|WP_012557492.1|1531354_1531822_+|hypothetical-protein
MGIIVWCVLFAIVIFFAFVVTRMAAQNKEDGLHDTGLAIIEFGRAFPNEAIRQLQATENGQAIFVRLHDNKAGFMRNMSRHFACHLIEPGRVRVVSSQTGRGLVIDFLDAPHHNGDFEFASAKESAEVALWLLGNYIAEPDKDLPSDHISAANKH
>NC_011369.1|WP_003586940.1|1530425_1531283_+|phytoene/squalene-synthase-family-protein
MVEAKPATNQETCLAMLRDSDRDRYLACLLSPEDKRGALAALYAFNAELARIRDLVHEPLPGEVRLQYWRDLLEGSAHGSTAANPVASALLTAIETHRLPRKTLIDMIEARTFDLYDDPMETRLSLEGYAGETASALIQLASLVLSPEEAARSADAAGHAGVAQAVAGLLLLMPLYRRRGQVYIPLQILSATGLNRDTFLAGEDRQRISAAIEAFAGLGREHLAKARAAGPIAPAVFPAFLPATLAEPVLFRAQKLGAVLFDRPLQPPQWRRQLSMALSAVRRKI
>NC_011369.1|WP_012557491.1|1530036_1530423_+|membrane-protein
MAKGIEIRAAHFPGRAPIDTYGNGGFRFADMSHRGSILCLPSGIHGWDMDMSKPLSPENFRRVLDEADDIEVLLVGTGTELRRLPEALKQALKARGIASDPMSTGAAVRTFNIMLAEQRAVAAALIAV
>NC_011369.1|WP_012557490.1|1527491_1530032_+|protein-translocase-subunit-SecDF
MLHFSRWKTLLIWLAAFAAIIIAAPNLLSEAQRSSLPGWLRQDRVTLGLDLQGGSHIVLKVERSDIVKDRLEEAVANVRNTLRGAGIRYTGLTGNDQTVTVRITDPAETQKAVELLKPLTTAGGRSGPEVALQQGEEGQLSLQISDAGITADVASARTRSLDIVARRIAGFGHANFIVRPDGTDRIVVQVLGSVDAERLKNLLNQPAKLSFHLIDASMSGQEALNGRWPATSQVLYSLDDPPVPYLVDRTAFLTGSNMVGIEPVVDPQTQDSSIAYRLDADGTRRLAEVTGQNIGKHLAIVFDDQVMSSPAIDAAITGGEGAISANFSEDGVRDLAIMLRAGALPATLTSVEERSVSPRFGADSIFSGLIAGLVAVVLVAALMIALYRILGVIAVVSLVFNLIFIVAALSLAGATLTLPGIAGIVLIVGMAVDSNVLIYERIREEEKTAHSFAEAAGRGFSRAFATIVDANVTIFIAAIILFFLGSESIRGFAVTLAVGILTTVFTAFTLTRSIVAVWLQRRHPRHLPKSVLTHLFEHANIRFMGIRRYVFTASAIISLIAMAAFATAGLRLGIDFTGGSLIEVTAKQGNADLADLQSRLNDLNLGEVSVTRAGGPSNARIRIASQGGGENAEQSAATLVRGELQEDYDFRRVEVVGPAISGELTMMATLGVLAALAAILIYIWVRFEWQFAVGAIVATLHDVIILLGLFVLTGMEFNLTSVAAVLTVVGYSLNDTVVVYDRMRENLKRYKKMPLPILIDASINQTLSRTILTAATTLLALLALYLFGGEVIRSFTFTMLFGVALGTFSSIYIAAPVLIVFRLRPESPDGEESNKTDAGVKSGTVV
>NC_011369.1|WP_003573534.1|1527098_1527446_+|preprotein-translocase-subunit-YajC
MFITPAFAQSATDTATGFGGSGFEMIILFVPLMVVWYFLLIRPQRAQAKKREETLKAIRRGDQVVTGGGLVGKVTKVIDDKEVEVEIADGVRVRIVRSGISDVRVKGEPVKADAA
>NC_011369.1|WP_012557497.1|1538688_1539126_+|nuclear-transport-factor-2-family-protein
MTAKNDMKKLVEDIYAVRGRGDIEGTLALFGEDCTFRMAGNARMAPLSTESGGPAFRQVIEQLITVWDLSKIKTTGIYVDEDEHMVFAHREGEVRHIPSGVSFHTEFVDKIHFKDGKPVKIVEFVDTLQVAEIAQINQVAQTSSR
>NC_011369.1|WP_012557498.1|1539178_1540954_-|radical-SAM-protein
MSHVLEAARRRFQLILIKPSHYDDDGYVIRWWRAMIPSNSLAALYGIAAECAERKVLGPDTAIDITVIDETNTRIDFAGLLAQFKRHDNFGMIALVGVQTNQYPRALDIARPFRDAGLPVSIGGFHVSGCLSMLDGKAVGLEACRDMGISMFAGEAEGRLEMVLRDAASGELKPLYNFMNDLPGIGGTPVPFLPKDNIQRTLGLSTSFDAGRGCPYQCSFCTIINVQGRKSRFRSADDVEKLVRMNWAQGIHKFFITDDNFARNKDWEAIFDRLIELKERDGIPLGLMIQVDTLCHKIPNFIEKSRRAGVTRVFIGLENVNPDNLTAAKKNQNKITEYRKMLLAWKAQGIMTLAGYILGFPADTPESIRRDIAIIQEELPLDVIEFFILTPLPGSEDHQVLWKKNVEMDSDLNIYDVEHVCTAHPKMSKQEWEDIYHEAWALYYSPDHMKTLLRRAVATGVPLARLVKVLVSFATTVPLENVHPLQSGLLRLKTPSERRPDLPRENPLVFWPRFAWDTFRKHASLAGTIIGLTISAFLISREAKSKTYMDQALTPVADDEEETLSLFTKTAGGTAAVSHVRKVAELTRTAH
>NC_011369.1|WP_012557499.1|1541110_1541914_-|endonuclease/exonuclease/phosphatase-family-protein
MRIISLNAWGGRLHEALIDYVRQAEADVLCLQEVLRAPGADWGWSIYRDAGLELPQRANLFAEISAALPGHDGFFCPTSRGELFNGDSAIAAEFGLATFVRKSHSVIAQGLDFVHGGFSANGWGEHPRPRNAHCIRVVSRENASSLTIAHMHGLRDPAGKSDTAARKKQAAALVALVERVWPGGEGLVVCGDFNVLPDSETFAILARLGLSELVTGNGLVDTRTSYYLKQGRFADYMLVTPEVKIARFEVVEAPEVSDHRALLLDIG
>NC_011369.1|WP_041671708.1|1541978_1543385_-|Si-specific-NAD(P)(+)-transhydrogenase
MLQYDLVVVGSGPAGRRGAIQAAKLGKKVLVIEQGKRVGGVSVHTGTIPSKTLRETALNLSGWRERGFYGRSYRVKEEISADDLRRRLLITLNHEVEVLEHQFARNRVQHIRGKASFINPSTLQVIKDDGEITQVTGASVLLAVGTKPFRPDYIPFDGKTVLDSDELLDIQELPRSMVVIGAGVIGIEYATIFSALDTAVTVIDPKATMLDFIDKEIVEDFTYQLRDRNMKLLLGQKADKVETLEGGKVELTLDSGRRLTTDMVLFAAGRMGATDALNLPAIGLEADSRGRLKVNPETFQTSVANVYAAGDVVGFPSLASTSMEQGRIAARVAIGAVAKEPPKYFPYGIYAVPEISTCGLTEEEMKERGIPYECGIARFRETSRGHIMGLDTGLLKLIFSLKTRRLLGVHIVGEGATELVHIGQAVLNLKGTVEYFVENTFNYPTLAEAYKIAGLDAWNRMGDIKSEL
>NC_011369.1|WP_148221745.1|1543485_1543602_-|DNA-repair-protein-RadC
MTMVIIDAANAFDIIVHDHIINGDVGLTGPTLIKHRSG
>NC_011369.1|WP_012557501.1|1543625_1544453_-|DNA-repair-protein-RadC
MAKRPVATSSDDELPFEIEEPVAADERAFFGGQPQKPAAANAKAALPASLAAQEHYHGHRERLRDRFREQGDTALADYEILELLLFRLIPRRDTKPIAKALIERFGSLAGVFGAPAALLTEVKGVGEAVALDLKLISTVAHRTLKSELRSKQVLSSWSSVIQYCHAAMAHETREQFRILFLDKRNVLIADEVQGRGTVDHTPVYPREVVKRALELSATAMILVHNHPSGDPTPSRADIDMTKVIIEAAKALDITVHDHVIIGKDGHVSLKGLKLI
>NC_011369.1|WP_012557502.1|1544460_1545297_-|type-I-methionyl-aminopeptidase
MVNYIEASSAPSKNTGAIRLYDAQAYEGMRRACQLTARCLDALADIVKPGLVTDDIDRFVFDFGMDHGAHPATLNYRGYTKSTCTSINHVVCHGIPNDKPLREGDIVNIDVTFVLDGWHGDSSRMYPVGTIKRAAERLLEVTYESLMRGISAVRPGARTGAIGEAIQTYAEAERCSVVRDFCGHGVGRLFHDSPNILHYGRANEGPELREGMIFTIEPMINLGRPHVKVLADGWTAVTRDRSLSAQYEHTVGVTSDGCEIFTLSPGGLDRPGLPSLAG
>NC_011369.1|WP_012557503.1|1545443_1546082_-|zeta-toxin-family-protein
MPELTCIILGGPNGSGKSSAFAKLDLEGVWINADEIAKSLPESDDGKSKERRASEVALRRIAEMIETRQSFVFETTLSSQQSLRLMREAKSAGFKVDLYYVALDSVETNVERVRQRVQKGGHNIPEADIRRRHKGSLAKLTDALTIADEVLLIDNSGLEPHAVFAISGGVVQSFDIDDSQELHYLMAAKVCEAYGLIWAHDGFRKSVSAGSK
>NC_011369.1|WP_003586920.1|1546092_1546269_-|hypothetical-protein
MLLRKYRENKEALKQIGREALAESRRMGLTISAKDRQNEAKDRAKRERNKDRAPATVR
>NC_011369.1|WP_012557504.1|1546485_1547145_+|TetR/AcrR-family-transcriptional-regulator
MLDEAVKLENLPEVGGEPERRVRDRGATERAILAAAKGLLAEEGFQNFGINAVARRAGCDKQLIYRYYGGLNGLVEAIGADLGTWVRDRIPEDAGGMFLLTYGDLMERLSLLLLEALRNDPLMRRILAWEISENTEQVRRLSEARSKALALWLERMRGSLAPPKGVDAAAVNAVIIAAIQHLVLAAASGGQCAGLSLKTPKDWEKAATALKRIVRGVYG

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NC_011369_2	2.1\|1525903\|58\|NC_011369\|CRISPRCasFinder	1525903-1525960	58	NZ_CP020951	Rhizobium sp. CIAT894 plasmid pRheCIAT894d, complete sequence	215728-215785	6	0.897

1. spacer 2.1|1525903|58|NC_011369|CRISPRCasFinder matches to NZ_CP020951 (Rhizobium sp. CIAT894 plasmid pRheCIAT894d, complete sequence) position: , mismatch: 6, identity: 0.897

cgcggttttcccaggcaaagcgcgaagcgcttttgccgcaacgacatgcgcaaaaacc	CRISPR spacer
agcggttttgccaggcaaagcgcgaagcgcttttgccgcaacgacatgcgtaaaacaa	Protospacer
 ******** ****************************************.****

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

1188556 : 1197620

Aeromonas_phage(14.29%)

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_003587436.1\|1188556_1189855_+	serine hydroxymethyltransferase	A0A219Y950	Aeromonas_phage	4.9e-98	51.3
WP_003547190.1\|1189864_1190341_+	transcriptional repressor NrdR	NA	NA	NA	NA
WP_012557273.1\|1190344_1191559_+	bifunctional diaminohydroxyphosphoribosylaminopyrimidine deaminase/5-amino-6-(5-phosphoribosylamino)uracil reductase RibD	A0A1V0SE20	Indivirus	2.6e-32	36.6
WP_003587434.1\|1191558_1192170_+	riboflavin synthase	A0A2I2L4R9	Orpheovirus	2.0e-17	35.6
WP_003587433.1\|1192208_1193078_-	glucose-1-phosphate thymidylyltransferase RfbA	K7QKA7	Escherichia_phage	1.5e-95	59.2
WP_012557274.1\|1193088_1193976_-	dTDP-4-dehydrorhamnose reductase	NA	NA	NA	NA
WP_012557275.1\|1193978_1195034_-	dTDP-glucose 4,6-dehydratase	I7HTA3	Enterobacteria_phage	6.3e-96	51.5
WP_012557276.1\|1195040_1195619_-	dTDP-4-dehydrorhamnose 3,5-epimerase	A0A218MN57	uncultured_virus	7.1e-33	45.6
WP_012557277.1\|1195643_1197620_-	hypothetical protein	Q6XM29	Feldmannia_irregularis_virus	3.7e-20	31.3

DBSCAN-SWA_2

1260383 : 1271164

Bacillus_phage(16.67%)

protease

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_174293595.1\|1260383_1261838_-	GGDEF domain-containing protein	A0A127AWB9	Bacillus_phage	4.6e-12	34.1
WP_003573944.1\|1262052_1262682_+	ATP-dependent Clp endopeptidase proteolytic subunit ClpP	A0A223W000	Agrobacterium_phage	1.6e-62	59.2
WP_003573940.1\|1262983_1264261_+\|protease	ATP-dependent Clp protease ATP-binding subunit ClpX	G3M9Z9	Bacillus_virus	1.3e-132	58.4
WP_012557323.1\|1264682_1267100_+	endopeptidase La	A0A0R6PGP8	Moraxella_phage	2.5e-204	49.4
WP_003573937.1\|1267306_1267582_+	HU family DNA-binding protein	A0A172Q061	Acinetobacter_phage	1.6e-06	33.0
WP_012557324.1\|1267970_1268870_+	DMT family transporter	NA	NA	NA	NA
WP_174293565.1\|1268953_1271164_+	esterase-like activity of phytase family protein	M4SLV1	Cyanophage	6.0e-80	42.9

DBSCAN-SWA_3

1517833 : 1530032

uncultured_Mediterranean_phage(90.0%)

tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_012557483.1\|1517833_1518691_+	segregation/condensation protein A	A0A1B1IVW1	uncultured_Mediterranean_phage	2.5e-34	37.6
WP_012557484.1\|1518687_1519404_+	SMC-Scp complex subunit ScpB	A0A1B1IVT7	uncultured_Mediterranean_phage	2.8e-39	48.1
WP_003538990.1\|1519585_1519777_+	twin-arginine translocase TatA/TatE family subunit	A0A1B1IVR9	uncultured_Mediterranean_phage	8.9e-09	72.1
WP_012557485.1\|1519828_1520455_+	twin-arginine translocase subunit TatB	NA	NA	NA	NA
WP_003586948.1\|1520451_1521279_+	twin-arginine translocase subunit TatC	A0A1B1IVR7	uncultured_Mediterranean_phage	1.2e-52	46.1
WP_012557486.1\|1521378_1522662_+\|tRNA	serine--tRNA ligase	A0A1B1IVT2	uncultured_Mediterranean_phage	1.7e-98	45.3
WP_003586945.1\|1522666_1523440_+	5'/3'-nucleotidase SurE	A0A1B1ITZ2	uncultured_Mediterranean_phage	3.1e-23	30.2
WP_012557487.1\|1523436_1524090_+	protein-L-isoaspartate(D-aspartate) O-methyltransferase	A0A1B1IU40	uncultured_Mediterranean_phage	8.9e-16	34.7
WP_012557488.1\|1524229_1525822_+	peptidoglycan DD-metalloendopeptidase family protein	I3PV24	Clostridium_phage	8.6e-12	29.2
WP_012557489.1\|1526022_1526895_-	ATP-binding protein	NA	NA	NA	NA
WP_003573534.1\|1527098_1527446_+	preprotein translocase subunit YajC	A0A1B1IVR5	uncultured_Mediterranean_phage	3.2e-12	38.0
WP_012557490.1\|1527491_1530032_+	protein translocase subunit SecDF	A0A1B1IVP7	uncultured_Mediterranean_phage	4.8e-57	48.2

DBSCAN-SWA_4

1781606 : 1791862

uncultured_Mediterranean_phage(66.67%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_012557662.1\|1781606_1784528_-	excinuclease ABC subunit UvrA	A0A1B1IVR3	uncultured_Mediterranean_phage	0.0e+00	62.1
WP_003586486.1\|1784808_1785315_+	single-stranded DNA-binding protein	R9TP78	Rhizobium_phage	7.1e-45	57.1
WP_012557663.1\|1785401_1786049_-	MarC family protein	NA	NA	NA	NA
WP_012557664.1\|1786298_1789124_+	DNA gyrase subunit A	G3M9Z5	Bacillus_virus	2.1e-98	33.4
WP_003586478.1\|1789485_1789641_-	hypothetical protein	NA	NA	NA	NA
WP_012557665.1\|1789783_1790062_-	hypothetical protein	NA	NA	NA	NA
WP_012557666.1\|1790167_1790662_+	pantetheine-phosphate adenylyltransferase	A0A1B1IVQ3	uncultured_Mediterranean_phage	1.8e-24	37.2
WP_003586475.1\|1790751_1791324_+	peptidylprolyl isomerase	A0A1B1IVS0	uncultured_Mediterranean_phage	3.7e-42	52.0
WP_003573154.1\|1791352_1791862_+	peptidylprolyl isomerase	A0A1B1IVS0	uncultured_Mediterranean_phage	3.2e-45	59.4

DBSCAN-SWA_5

2462233 : 2490871

Sinorhizobium_phage(61.54%)

terminase,tail

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_012558202.1\|2462233_2462698_-	lysozyme	A0A0K1LL70	Rhodobacter_phage	2.0e-25	44.7
WP_012558203.1\|2462672_2462927_-	hypothetical protein	NA	NA	NA	NA
WP_012558205.1\|2463531_2463720_+	hypothetical protein	NA	NA	NA	NA
WP_012558206.1\|2463722_2464283_-	acyltransferase	A0A2R8FE91	Brazilian_cedratvirus	6.1e-05	44.6
WP_012558207.1\|2464367_2466839_-	hypothetical protein	A0A076G7H5	Sinorhizobium_phage	4.7e-49	53.1
WP_012558208.1\|2466852_2469054_-	hypothetical protein	A0A076G8H4	Sinorhizobium_phage	9.0e-270	66.2
WP_012558209.1\|2469050_2469467_-	hypothetical protein	A0A076G6J4	Sinorhizobium_phage	3.2e-35	53.7
WP_012558210.1\|2469473_2470088_-	hypothetical protein	A0A076G707	Sinorhizobium_phage	4.7e-75	66.7
WP_012558211.1\|2470088_2470820_-	hypothetical protein	A0A076GD29	Sinorhizobium_phage	1.4e-78	57.4
WP_012558212.1\|2470822_2473696_-\|tail	phage tail tape measure protein	A0A076G7H2	Sinorhizobium_phage	1.8e-214	50.9
WP_012558213.1\|2473699_2473993_-	hypothetical protein	A0A076G6J1	Sinorhizobium_phage	5.2e-32	62.9
WP_012558214.1\|2474046_2474460_-	hypothetical protein	A0A076G701	Sinorhizobium_phage	9.2e-51	75.2
WP_012558215.1\|2474459_2475200_-	hypothetical protein	A0A076GD25	Sinorhizobium_phage	5.4e-94	72.0
WP_012558216.1\|2475258_2475690_-	hypothetical protein	A0A076G7G6	Sinorhizobium_phage	6.9e-65	81.8
WP_012558218.1\|2475879_2476326_-	hypothetical protein	A0A076G8G8	Sinorhizobium_phage	3.4e-43	60.4
WP_012558219.1\|2476325_2477378_-	hypothetical protein	A0A076G6I6	Sinorhizobium_phage	1.1e-113	63.6
WP_012558220.1\|2477377_2477545_-	hypothetical protein	NA	NA	NA	NA
WP_012558221.1\|2477611_2478244_-	hypothetical protein	NA	NA	NA	NA
WP_012558222.1\|2478307_2478682_-	hypothetical protein	A0A076G8G5	Sinorhizobium_phage	2.1e-33	60.2
WP_012558223.1\|2478678_2479173_-	hypothetical protein	A0A2R3UAR2	Siphoviridae_environmental_samples	2.5e-18	40.7
WP_012558224.1\|2479178_2479541_-	hypothetical protein	NA	NA	NA	NA
WP_041671729.1\|2479610_2480594_-	DUF2184 domain-containing protein	A0A2D2W280	Sinorhizobium_phage	1.1e-89	54.8
WP_012558226.1\|2480639_2481107_-	hypothetical protein	A0A2D2W1Z4	Sinorhizobium_phage	4.3e-20	45.6
WP_012558227.1\|2481110_2482238_-	DUF2213 domain-containing protein	L7TMD6	Rhizobium_phage	3.0e-88	48.8
WP_148221749.1\|2482288_2482963_+	SLATT domain-containing protein	NA	NA	NA	NA
WP_012558229.1\|2482918_2484307_-	DUF1073 domain-containing protein	L7TRA1	Rhizobium_phage	3.0e-122	52.6
WP_012558230.1\|2484316_2485705_-\|terminase	phage terminase large subunit	W8E9V1	Pseudomonas_phage	8.1e-75	36.3
WP_012558231.1\|2485691_2486156_-	DUF2280 domain-containing protein	A0A125RNL6	Pseudomonas_phage	7.7e-38	57.0
WP_012558232.1\|2486192_2486438_+	hypothetical protein	NA	NA	NA	NA
WP_041671473.1\|2486434_2487019_-	hypothetical protein	A9YWZ4	Burkholderia_phage	1.7e-50	51.9
WP_012558235.1\|2487894_2488152_+	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_012558236.1\|2488268_2488952_-	hypothetical protein	A0A076G6H3	Sinorhizobium_phage	6.2e-36	44.1
WP_012558237.1\|2488981_2489446_-	hypothetical protein	NA	NA	NA	NA
WP_012558238.1\|2489445_2489742_-	hypothetical protein	NA	NA	NA	NA
WP_012558239.1\|2489738_2490500_-	YdaU family protein	A0A0U2RT81	Escherichia_phage	8.8e-15	44.2
WP_012558240.1\|2490496_2490871_-	DUF1064 domain-containing protein	A0A0R6PIG9	Moraxella_phage	1.6e-09	41.4

DBSCAN-SWA_6

3611112 : 3621154

Mycobacterium_phage(25.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_012559064.1\|3611112_3611823_+	7-cyano-7-deazaguanine synthase QueC	A0A2P1JXV3	Rhodococcus_phage	6.0e-50	48.7
WP_012559065.1\|3611822_3612179_+	6-carboxytetrahydropterin synthase QueD	NA	NA	NA	NA
WP_012559066.1\|3612175_3612904_+	7-carboxy-7-deazaguanine synthase QueE	A0A1U9WRB6	Streptococcus_virus	8.1e-42	39.0
WP_012559067.1\|3612916_3614140_-	adenylate/guanylate cyclase domain-containing protein	M1HLN3	Pelagibacter_phage	1.4e-14	29.9
WP_012559068.1\|3614239_3615214_-	class 1b ribonucleoside-diphosphate reductase subunit beta	R4TBI6	Mycobacterium_phage	5.1e-140	75.4
WP_012559069.1\|3615230_3617435_-	class 1b ribonucleoside-diphosphate reductase subunit alpha	A8E2R1	Enterococcus_phage	3.6e-210	51.8
WP_012559070.1\|3617413_3617818_-	class Ib ribonucleoside-diphosphate reductase assembly flavoprotein NrdI	A0A142F1R4	Bacillus_phage	6.5e-17	44.8
WP_012559071.1\|3617833_3618055_-	glutaredoxin-like protein NrdH	V5UN81	Mycobacterium_phage	7.9e-17	53.4
WP_012559072.1\|3618877_3621154_-	cadmium-translocating P-type ATPase	E4ZFI9	Streptococcus_phage	1.8e-127	41.4

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. NC_011369

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection