CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NC_011835	Bifidobacterium animalis subsp. lactis AD011, complete sequence	7 crisprs	csb3,cas3,cas7,cas2,cas1,WYL	1	9	1	0

Results visualization

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CRISPR-Cas detection and classification

Crispr_ID: NC_011835_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_011835_1

183654-184039

Orphan

Consensus_repeat	Method
GGTCGGTTTTGCGGATGCTTCCG	CRISPRCasFinder

7 spacers

The CRISPR arrays of NC_011835_1

>merge|NC_011835|1|183654-184039|CRISPRCasFinder
GGTCGGTTTTGCGGATGCTTCCGTATGGCATGCCGTTTTCAGACTTCTTCGCGGTCGGTTTTGCGGATGCTTCCGAAAGCTATGCTGTTTTCAGACCATTCCGTGGCGCGTTTCTCGGATACCTCCGAGAGGCATGCCATTTTGGAGCCTTCTGGCAGTACGTTTCTCGGATGCTTCCGTACGCTGTGCTGCGGGGAAGACGGCCTGCGGTTTGGTTCTCGGATGCTTCCGTGAGATGTGCCTCTGATGGGGTGGTTTCTGGCCCATCTCTCGGATGCGTCCGTATGCTGTGCCGCTGCAGGGGTGGTTTGCGGTCCGTTGTGCGGATGCTTCCGTAGGCTGTGCCATTTTAGATTCCTTTGTGGCACGTTTCTCGGATGCTTCCG

>NC_011835|1|1|183654-184039|CRISPRCasFinder
GGTCGGTTTTGCGGATGCTTCCG	TATGGCATGCCGTTTTCAGACTTCTTCGC
GGTCGGTTTTGCGGATGCTTCCG	AAAGCTATGCTGTTTTCAGACCATTCCGT
GGCGCGTTTCTCGGATACCTCCG	AGAGGCATGCCATTTTGGAGCCTTCTGGC
AGTACGTTTCTCGGATGCTTCCG	TACGCTGTGCTGCGGGGAAGACGGCCTGC
GGTTTGGTTCTCGGATGCTTCCG	TGAGATGTGCCTCTGATGGGGTGGTTTCT
GGCCCATCTCTCGGATGCGTCCG	TATGCTGTGCCGCTGCAGGGGTGGTTTGC
GGTCCGTTGTGCGGATGCTTCCG	TAGGCTGTGCCATTTTAGATTCCTTTGT
GGCACGTTTCTCGGATGCTTCCG

Protein	Signature genes	Signature genes Name	Protein_function
NC_011835.1\|WP_004218471.1\|195577_197413_+\|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|224055
NC_011835.1\|WP_072633038.1\|189731_190190_-\|ABC-transporter-permease	unknown	unknown	unknown
NC_011835.1\|WP_004268961.1\|187933_189478_+\|amino-acid-permease	unknown	unknown	gnl\|CDD\|224038
NC_011835.1\|WP_004218468.1\|191804_192227_-\|ATP-binding-cassette-domain-containing-protein	unknown	unknown	gnl\|CDD\|224059
NC_011835.1\|WP_004218455.1\|178580_179846_+\|AGE-family-epimerase/isomerase	unknown	unknown	gnl\|CDD\|369267
NC_011835.1\|WP_004218451.1\|176356_176992_-\|YesL-family-protein	unknown	unknown	gnl\|CDD\|377412
NC_011835.1\|WP_004218467.1\|190086_191808_-\|ABC-transporter-permease	unknown	unknown	gnl\|CDD\|223650
NC_011835.1\|WP_004218448.1\|172238_173621_+\|beta-glucosidase	unknown	unknown	gnl\|CDD\|274539
NC_011835.1\|WP_004218456.1\|180373_181114_+\|ATP-binding-cassette-domain-containing-protein	unknown	unknown	gnl\|CDD\|182331
NC_011835.1\|WP_004218449.1\|174050_174788_+\|hypothetical-protein	unknown	unknown	unknown
NC_011835.1\|WP_004218461.1\|184924_187879_+\|FtsX-like-permease-family-protein	unknown	unknown	gnl\|CDD\|223650
NC_011835.1\|WP_004218469.1\|192921_193515_+\|MarR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|197670
NC_011835.1\|WP_004218453.1\|177075_177807_-\|hypothetical-protein	unknown	unknown	unknown
NC_011835.1\|WP_004218470.1\|193586_195506_+\|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|224055
NC_011835.1\|WP_004218457.1\|181115_181982_+\|iron-export-ABC-transporter-permease-subunit-FetB	unknown	unknown	gnl\|CDD\|377092
NC_011835.1\|WP_004218459.1\|184212_184914_+\|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|213222
NC_011835.1\|WP_004218454.1\|178105_178267_+\|hypothetical-protein	unknown	unknown	unknown
NC_011835.1\|WP_004218450.1\|175044_176073_+\|LacI-family-DNA-binding-transcriptional-regulator	unknown	unknown	gnl\|CDD\|224525
NC_011835.1\|WP_004218458.1\|182134_183631_+\|amino-acid-permease	unknown	unknown	gnl\|CDD\|224038
NC_011835.1\|WP_004218464.1\|189489_189735_-\|FtsX-like-permease-family-protein	unknown	unknown	gnl\|CDD\|226957

Protein	Function_ID	Function_description	E-value
NC_011835.1\|WP_004218471.1\|195577_197413_+\|ABC-transporter-ATP-binding-protein	gnl\|CDD\|224055	COG1132, MdlB, ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms].	0
NC_011835.1\|WP_004268961.1\|187933_189478_+\|amino-acid-permease	gnl\|CDD\|224038	COG1113, AnsP, Gamma-aminobutyrate permease and related permeases [Amino acid transport and metabolism].	1.70709e-147
NC_011835.1\|WP_004218468.1\|191804_192227_-\|ATP-binding-cassette-domain-containing-protein	gnl\|CDD\|224059	COG1136, SalX, ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms].	4.3829e-49
NC_011835.1\|WP_004218451.1\|176356_176992_-\|YesL-family-protein	gnl\|CDD\|377412	pfam04854, DUF624, Protein of unknown function, DUF624. This family includes several uncharacterized bacterial proteins.	7.22333e-11
NC_011835.1\|WP_004218455.1\|178580_179846_+\|AGE-family-epimerase/isomerase	gnl\|CDD\|369267	pfam07221, GlcNAc_2-epim, N-acylglucosamine 2-epimerase (GlcNAc 2-epimerase). This family contains a number of eukaryotic and bacterial N-acylglucosamine 2-epimerase (GlcNAc 2-epimerase) enzymes (EC:5.3.1.8) approximately 500 residues long. This converts N-acyl-D-glucosamine to N-acyl-D-mannosamine.	5.66098e-127
NC_011835.1\|WP_004218448.1\|172238_173621_+\|beta-glucosidase	gnl\|CDD\|274539	TIGR03356, BGL, beta-galactosidase.	0
NC_011835.1\|WP_004218456.1\|180373_181114_+\|ATP-binding-cassette-domain-containing-protein	gnl\|CDD\|182331	PRK10247, PRK10247, putative ABC transporter ATP-binding protein YbbL; Provisional.	4.31445e-39
NC_011835.1\|WP_004218450.1\|175044_176073_+\|LacI-family-DNA-binding-transcriptional-regulator	gnl\|CDD\|224525	COG1609, PurR, Transcriptional regulators [Transcription].	2.91291e-76
NC_011835.1\|WP_004218461.1\|184924_187879_+\|FtsX-like-permease-family-protein	gnl\|CDD\|223650	COG0577, SalY, ABC-type antimicrobial peptide transport system, permease component [Defense mechanisms].	1.32837e-12
NC_011835.1\|WP_004218469.1\|192921_193515_+\|MarR-family-transcriptional-regulator	gnl\|CDD\|197670	smart00347, HTH_MARR, helix_turn_helix multiple antibiotic resistance protein.	1.25581e-13
NC_011835.1\|WP_004218470.1\|193586_195506_+\|ABC-transporter-ATP-binding-protein	gnl\|CDD\|224055	COG1132, MdlB, ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms].	1.18215e-139
NC_011835.1\|WP_004218457.1\|181115_181982_+\|iron-export-ABC-transporter-permease-subunit-FetB	gnl\|CDD\|377092	pfam03649, UPF0014, Uncharacterized protein family (UPF0014).	8.05493e-81
NC_011835.1\|WP_004218459.1\|184212_184914_+\|ABC-transporter-ATP-binding-protein	gnl\|CDD\|213222	cd03255, ABC_MJ0796_LolCDE_FtsE, ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein. This family is comprised of MJ0796 ATP-binding cassette, macrolide-specific ABC-type efflux carrier (MacAB), and proteins involved in cell division (FtsE), and release of lipoproteins from the cytoplasmic membrane (LolCDE). They are clustered together phylogenetically. MacAB is an exporter that confers resistance to macrolides, while the LolCDE system is not a transporter at all. An FtsE null mutants showed filamentous growth and appeared viable on high salt medium only, indicating a role for FtsE in cell division and/or salt transport. The LolCDE complex catalyzes the release of lipoproteins from the cytoplasmic membrane prior to their targeting to the outer membrane.	2.55179e-99
NC_011835.1\|WP_004218467.1\|190086_191808_-\|ABC-transporter-permease	gnl\|CDD\|223650	COG0577, SalY, ABC-type antimicrobial peptide transport system, permease component [Defense mechanisms].	4.61117e-28
NC_011835.1\|WP_004218458.1\|182134_183631_+\|amino-acid-permease	gnl\|CDD\|224038	COG1113, AnsP, Gamma-aminobutyrate permease and related permeases [Amino acid transport and metabolism].	2.07775e-179
NC_011835.1\|WP_004218464.1\|189489_189735_-\|FtsX-like-permease-family-protein	gnl\|CDD\|226957	COG4591, LolE, ABC-type transport system, involved in lipoprotein release, permease component [Cell envelope biogenesis, outer membrane].	0.00288599

>NC_011835.1|WP_004218458.1|182134_183631_+|amino-acid-permease
MSASHGAGERNADPQQLHKSLKNRHIQLIALGGAIGTGLFYGSSESIALAGPSILLAYVIGGAAIFVIVRAMSEMSVEEPKAGAFSYYASRYWSKRAGFISGWNYWFNYVLVSMVELAVVGSFVNYWFPNIPQWASAAFFLVLITLLNLFGVSEFGEFEFWFALIKIVAVIAMIAGGLWVIVANLPTDSGVRASFANWFTVDGGFFPHGAMSRAADGHWDGLLMALVVVMFSFGGTELIGVTAGEVENPSKTIPRATNGIIWRILVFYVAALGIIMAVVPWDRIDGKMSPFVQIFDSVGVPVAAGILNFVCLTAVMSVYNSALYSNSRMLFSLARQGNAPAYLGRVNKRGVPVAGVLTSAAVTVVAVVVVFLWPQFAFNYLMSIATIAAIINWTMIMITEMLFRRRVAAGDGPGELNGLRGAEALAKIRFKLPGWNWTPYVIIAFLAMVAVLMCFSPSYRIALIAGVIWLAVLFAAYAITSRASAKRDAKTVLDSTRK
>NC_011835.1|WP_004218457.1|181115_181982_+|iron-export-ABC-transporter-permease-subunit-FetB
MQQYFAIDNWGLLIAVLMVCIAAGVSALMKLGVAKSLLWATARSLVQLLAMGFILEYVIRAQNVWLVIGLIVVMLVAAAQITMSRAKGIPKGLVPLVLLSLAVTMLLMLALVGELVIRPNPWYSPQLIIPLTGMLLGNTVSALALGLSRFFNSMRERYEEVNTLLALGATPWEAAKPSITSSITLGLLPSIAMLASSGIVTIPGMMSGQIIAGQNPVNAAKYQFVILAAVSALTLLADSIILALVYKRCFISYDRYFVPPARDSVSTLDRIRRQAAERANRGPESAGE
>NC_011835.1|WP_004218456.1|180373_181114_+|ATP-binding-cassette-domain-containing-protein
MGSMSSAHDFHATGVTAVVNNDAGGTRTIFKDLSFAVHGGEIVDITGPSGSGKSTLLTSFARLNVNTTGKFVLDGVDSDTLSPQQWRERVAYLPQTSVLIGDNVADAIRLPWSLKIRVSQDHEAAEQKLPDSLIRSTLDSLGCDDIDLARAVQDLSGGQAARVSLTRTLLTHPGVLLADEVDAGLDEENADKVADILRKAADNGTAVVRIRHRKPDGRANRIMVLANGTISPLKTAQSAPSTHTEV
>NC_011835.1|WP_004218455.1|178580_179846_+|AGE-family-epimerase/isomerase
MANTDPKYQIGTPENKKFLDISRDNLIAFGRRFPAVDGSSYWLGDDGTPWKDRNRATWITCRMTHVYSLATLLGVDGAAELVDDGIRGLRGVLHDEEHDGWYAEITPDICHMPTKQAYAHAFVLLAASSALLAGRPGAKELLEQAENVYLTKFWDDKIGLSVDTWDTDFAELDTYRGLNANMHSVEACLAVADVTGDESWRTRAGRIIEHVLKWAEENNWRIPEHFNSDWEPELEFNADKPDDQFKPYGATPGHGIEWARLITQYALSVYGKDGVLNGDGKKYLDAAEHLFNRAVEDAWNADGAPGIVYTTDWDGKPVVHDRMHWTLAEGVNTAATLYHVTGKKEYADWYATFLEYIDTYLMDHKNGSWFHQLNRENEVIDTVWPGKSDLYHATQAMMIPLRDPALSIAPATKKGVEEGLN
>NC_011835.1|WP_004218454.1|178105_178267_+|hypothetical-protein
MYDEGPHIVLRRDGVCIVAKTPDGDMPQIEYWGRDFAFDTAGDALRQLDMRAI
>NC_011835.1|WP_004218453.1|177075_177807_-|hypothetical-protein
MEGKQPKLTPEQREAIDTLSSTPQYQGESKIKIFMKIPAKDKAAYSRTHFLVPLLAAVIVIALGTFVIVRLVSPVPRPALYAAAVSGSTPMGEADKLKDDYAKKLGKDVIIDDYFDMNKDGLSKLQTMIGNEQIDVVIAPHDVFAKLASFGYFDNLKTTLPAAEYAKVGKYAMAFHGFDDSRVTDAIDESGSGQGKSEPYGLLLEHAPRWDRIEGADDDALVGIAANTQQLDTAKNFIQYLYN
>NC_011835.1|WP_004218451.1|176356_176992_-|YesL-family-protein
MIAGGIFRQDNPYNTVMNRIGDIAMLSVAWFVCCLPVVTIGVSTAAACEVAREMQEDRDNGIFKGFWRAIKRRFGTGMLLTLFLGVLIALGAFDLWWISRSMAGDMASVLYGVTLAVFIIVAMLFAFLLPLSGRSKLSAGEQIKQSAKLATMKPFIALVVAAIYALPIVLLATLPSAVMWVPLVWCIFGGGASAWAQMWLIRRAFDLQPQD
>NC_011835.1|WP_004218450.1|175044_176073_+|LacI-family-DNA-binding-transcriptional-regulator
MVAQKAKVTIFDVAKASGVSSSAVSYALNGKPGVSDATREKVLQVARKLGWRPNGAAQSLAQSRTRRIGLVLGYDPQLLSAEPYIMRLISGLGSALEERDYSLLVRMSMDDDDEVSILEDWIATGNVDALLLLNLEIGDPRIELMKNNPQMPCLALADSSLTSGLPTLMSDDAAASGTMIRHLALFGHKNIARVAGPEELGHSYIRDAAFSEITTELGMRYRCLHTDYTPESGAEATKRLLSVEPRPTAIIYDNDVMALAGESVASVKGVRVPEDLSIISWGDSFMNVAAHPPITALSRNILESGRLAAQLMLKLIDGEDVENVEEPPYELIERASTAPAAQ
>NC_011835.1|WP_004218449.1|174050_174788_+|hypothetical-protein
MKVKKIAAIALASACAFSMAAVDFNGHRKPVWYASRDFFAPRLATIQPRTSEEYRETHSWEGVKVDADHLELIVLNDTNEPYKGSWAVNRVDFDGNVLATQQIDDVELDAASHKGFPLNEEIVDFGDANNELIVAVPSDDSFARVIYNPAEILTQELDAPADAFTTKAKRTADGVELTVTANDYVRDLFCMVGKVDDKATVEEGLVSLLPGESVTFHIGTDYAGDPADFAAANVLRSANDLKRDF
>NC_011835.1|WP_004218448.1|172238_173621_+|beta-glucosidase
MTMTFPKGFQFGTATAAYQIEGAVDEDGRTPSIWDVFSHAPGRVLNGDTGDKADDFYHRWQDDLKLVRDLGVNAYRFSIGVPRVIPTPDGKPNEKGLDFYERIVDQLLEYGIDPIVTLYHWDLPQYLNEDPYRDGWLNRETAFRMAEYAGIVAKRLGDRVHTYTTLNEPWCSAHLSYGGTEHAPGLGAGPLAFRAAHHLNLAHGLMCEAVRAEAGAKPDLSVTLNLQVNRGDADAVHRVDLIANRVFLDPMLRGYYPDELFAITKGICDWDFVHDGDLKLINQPIDVLGLNYYSTNLLAMSDRPQFPQSTEASTAPGASDIDWLPTDGPHTQMGWNIDPDALYNTLVRLNDDYDHIPLVVTENGMACPDEVEVGPDGVKMVHDDDRIDYLRRHLEAVHRAIEEGANVIGYFVWSLMDNFEWAFGYDRRFGLTYVDYDTEERIRKDSYNWYRNFIAEHSAK
>NC_011835.1|WP_004218459.1|184212_184914_+|ABC-transporter-ATP-binding-protein
MAYIEFNDVVKEYPAGSSSIRALDGASFAADEGELSVILGQSGAGKTTALNILGGMDTATSGRVIVGGRDITDLNHHDLVTYRRNDIGFVFQFYNLIPNLTALENVELASQICTDHFDPAQTLAKVGLADRLGNFPAQLSGGEQQRVSIARALAKKPKLLLCDEPTGALDYETGKEVLQLLQDICRTERMTVLIVTHNSALAPMAHKVIRFRSGKVTSQETNEHPVPISQIEW
>NC_011835.1|WP_004218461.1|184924_187879_+|FtsX-like-permease-family-protein
MARRKGVPVGDADVHAQIADSGSLHAEHGHARAVGSAFLLDTMRSGLHAWKPFLSILIITMLGVAVLTGIYAGCRDTFAAANRFYRAQGLHDVQVISTMGLTDADVDALRQVEGVEQAQGMRMIRVKVADGDGKQLNATLEEPASGSPAALDRPYVNEGWLPSKPGEVAVTAQFTHDTHKKLGDTVEVAADGEDDGTHGLKIVGIVTDPSDLTNPGGYSGSAFRSSVTNDYTFYTAPDGIQRTFVKADGTPIAAADPKVYGSIVLRLDDAENEDAFTASYDDLVSGTVKRIENGVQAKREQARRNALVEEAQNKLDAEKKKAFDQIDAAQAKLDAQRRQLDDQLKQLDAQTAQIPVGVPEPAQLAEAQRQWAAADTKLREAQQAIDTQRNEAFSAFAAEQQKVDGIATPRWYVQSRSALAGFSSLKSDISSIESLGKAFPIVFLVVAVMMSLTTMSRLVEEDRGLVGTYLGLGYGRIAITLRYALFALLACLIGGGLGLLIGFLGIPAFLLVVIRGLYAIPDLRLEYDWLYGSLGVLLFVVGVLGAALIASVREMRQMPAALMRPKAPKAGSRILLERVRPLWSRMSFLNKVTARNIFRFKARLIMTVGGVAGCTALILCGLAINDTVAALGPNQYRGVDQYDMLAVANDGDEQALRKKLVSDGTTTAIMETRIENGEITNANDRGTNVQLTVVPQRQLGELNTMFDLQPAQGDSLLGWVHGGNRNQPVRLDNSGIIVAQSAAQSLGIKAGSEVTLRGDGTQPHKVKVAQVTRSLIGAEAFISEDLYHQLFPAQQAGDGGTEPAITWNAVYAKLKGSDSEQSEYVQHLKNEATVMSATSCAQQAEDFKFDLMGAVVALIVALAGSLALVVLFTLAHTNVSERLREMATLKVLGFYGREVHHYVNREMMVLTVMGIVIGLPLGRWVSGLLTNALNMPGIYFEVHISWWSYIITVVATLAFAWLVQLFVNPVLDRIDPVSSLKSVE
>NC_011835.1|WP_004268961.1|187933_189478_+|amino-acid-permease
MSDVQQPAEPHETPHEEEVNASLETLDKDNEMERGLSNRHVQFIAIGGAIGTGLFLGSGKSINLAGPNIIFVYILVGGIMFLMMRAIGELMYRDPSQHTFINFIRFYLGDGWGKFALWSYWIVLILIGMTEITAVGQYCVTFFRTLGYDVSAWKGLIELGFLLLLVMINLIAVKAFGEAEFWFSMIKITLIVAMIATAVIMLVCGFKYNAVQVPGQDHVSPAGSVTLDNLTRGFSLAPNGWLAFLMSFQMVFFAYEMIEFMGVTVSETKNPRKVLPKAINGIIVRVLIFYVGALLAIMTIVPWRNFRPNKDGSFASPFIMVFEYAGANWAAALVFFVVVTAAASSLNSLLYSAGRHLYEIAEDSPSPAIAKLGVVSKTKVPARAIIASAILVLLSPVIEMIPRVSGAFVMFSSASSAVIIFIYILTMIAHYRYRNSPQFMANGFRMPAYRVLNPLTTAFFVFIYCTLFIGADTRGPAIAGLVWLVVFGGYCVLHERFQNRDLKQSIDSAGDAHA
>NC_011835.1|WP_004218464.1|189489_189735_-|FtsX-like-permease-family-protein
MIAIESVILSVFGTVLGILVGLGAGVVVRQAYRDNGLSTMSIPWLQLLGFLGAAILVGLIASISPASRALKKPVLEAVASD
>NC_011835.1|WP_072633038.1|189731_190190_-|ABC-transporter-permease
MLASVSDMIDDNLHADYVLVSAALSQSVSPKAVNDVKHTAGVGATTAVRTLPTVKLMQANEQFTAMAVDRELLDAMYPATHQEGDAAQAIEHGEIAVGRKVADSNGYAIGSTVEMESKNIGIDEAATKQAIAAYEQQVGEQVSVHRTGRYVA
>NC_011835.1|WP_004218467.1|190086_191808_-|ABC-transporter-permease
MIRIGLRDAKAHFHRLVMSIIAIALGVSFVVGSFCFRSMLNDQVTQLMGTNSDHDVYVRGTTEEQNDSSFATSGPISSGTSYNKIDTSLVTQIEQVKGIDNVSPPERTIGATLLDHDGNAVVTTGAPTLMISASSEHPWRAANFIAGTYATGEHEIALSQDAAKKAGLQVGDTTRLIVNGEPHTMKVSGVFTTQTAELGVLIILAQPALVNQLMQLQGEDTSKVDKIGVYGNRTTPLTVQKQHQLADRINKALPKDSKAHAVTGQSVRDEATKSTQESLGFVQPLILIFAVIALFVGAFIIANTFTMIVRDSMRGYALLRSVGASPAQVFFSVVIQALILGVIGSVLGVLLGWGLIELIDWGLSKGGFPLSGSPTPSPTAVAVGFMVGVVVTVIGSAIPARTAATAPPIQAMNETMNPEKPVTARGWIGAGMVAFGALCWLLCWLLAAKKVSWAWLTTVGTGWLLGLGGVCTAGGVIVLAPALVTGAAKVLGWLPSRIPGDRHAGHPQHRPHETSHRQHGRRPVRGRGNRQLPERARLVNARLGERYDRRQSSCRLCARLRRALAIRLAEGRQ
>NC_011835.1|WP_004218468.1|191804_192227_-|ATP-binding-cassette-domain-containing-protein
MDWFDKVVSVVKLQNRLDHRPSQLSGGQQQRVACARAIMERPSVIFADEPTGNLDSRSSHEVFEFLRMCVREYGQTIVMVTHDPRAASFADRVLVLSDGSIVQDLDHPSYDDILAVFAQDDDPQNGPVEVESATARSAEQ
>NC_011835.1|WP_004218469.1|192921_193515_+|MarR-family-transcriptional-regulator
MDYQLEAVHELMFAMWASRSKATRSFERGAQGEMFVLRELSFQGARTPSQLAQAMGATSGRISSILASLTKKGWIVRTGDPQDRRSVVVELSDEGRRAVRQRSDRLIENLSWVFSQMGERRTREFVGLLSEFMTYLSICEPDGSYPTVEQVEEAFERRARLHERMREMVRNGEQWHGSCRPHDAPSSNDADVDRPVQ
>NC_011835.1|WP_004218470.1|193586_195506_+|ABC-transporter-ATP-binding-protein
MIRIMKYLSKTEIGQLVLSLVTIVGQVYFDLELPSYMSQITRLVETPGSQMRDIWIAGGKMLLVSLGSLACAVITGYFAARVAASFGQRLRSLEFRKVESFGPSEMHRFSTASLITRSTNDITQIQMFITMGLQMLIKAPIMAVWAVCKIAGEGFEWTLATGIAVAILIISIAVLMVLVMPKFKAMQQLTDDINLVTRENLTGMRVVRAYNAQDYQEGKFERANSNLTNTQLFTNRAMSVMMPLMGTIMNGLSLAIYWIGAYLIQDAGLTDKLTLFSNMVVFSSYAMQVVMSFLLMSMVFVLWPRADVSAHRVLEVLDTDPLVKSGTAERGLTVQEAKQRGIITPAERARYADDLELAGEIEFRDVSFTYPDSREAMLEHISFTANRGDTVAIIGSTGSGKSSLINLVPRFYDATDGEVLVDGVNVREYDLKTLRDKIGYVPQRSFLFKGTVESNVSYGDRPDEPEDVPVIDVSRMSGRKAEREFLKAGEARELTAQEANRVREASDIAQATEFVSKMPKGFQSPIAQGGTNVSGGQKQRLSIARAVYRDPEILIFDDSFSALDFKTDREVRDALKETAKDATKLIVAQRVGTIMDADCILVLEDGKVVGQGTHRELLETCEVYQEIAKSQLSEEELSA
>NC_011835.1|WP_004218471.1|195577_197413_+|ABC-transporter-ATP-binding-protein
MGHGRAGAPVEKADDFGGALKELMRFSKRYIPAIVIALILGVGGAICQIIGPDYLGDMTDEITKGLPALVHGKPVLRSIDMTAVTRIGWTLVALYVGYALLSYVQSWMMATVTQRTAQRLRAAIDVKMNKLPLKYFDEHSTGDVMSRITNDVDAVGQTLGQSLGTLISSVTLFVGSLVMMFANNWILALCAVGATLLGMVLMLVVMRFSQKYFVKQQMALGDVNGHVEEMYSGHTVVKAFGGEADAIRRFERYNNDLYDSGWKSQFISGLMMPMMNLVGNLGYVVVCVVGAALAMNGSIEFGVIVAFMLYIRLFTQPLSQFAQAFQNLQRCAAGSERVFTFLDEPELADESDKQPLLGYGSNGEITPVEGRVSFEHVKFGYEPNKLVIHDFSADVEPGQKVAIVGPTGAGKTTMVNLLMRFYEIAGGKISIDGIDTKSVPRWNVHDQFSMVLQDTWVFNGTVRENVAYAKEDVTDEQVVAACRAVGLDRYIRSLPNGYDTVLDESATLSQGQKQLLTIARAMVQDSPILILDEATSSVDTRTEELIQTAMDKLTEGRTSFVIAHRLSTIRDADMILVMRDGDIVERGTHEELLAKHGFYADIYNAQFTLAQ

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Crispr_ID: NC_011835_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_011835_2

219431-219514

Orphan

Consensus_repeat	Method
TTTCCGTCTCTTTTTACGCAGAA	CRISPRCasFinder

1 spacers

The CRISPR arrays of NC_011835_2

>merge|NC_011835|2|219431-219514|CRISPRCasFinder
TTTCCGTCTCTTTTTACGCAGAAAGGGCCGGTTTGCGTAATTGGGGACATCGCTGGGCTGCTTTCTGTCTCTTTTTACGCAGAA

>NC_011835|2|2|219431-219514|CRISPRCasFinder
TTTCCGTCTCTTTTTACGCAGAA	AGGGCCGGTTTGCGTAATTGGGGACATCGCTGGGCTGC
TTTCTGTCTCTTTTTACGCAGAA

Protein	Signature genes	Signature genes Name	Protein_function
NC_011835.1\|WP_004218499.1\|226468_227848_+\|replicative-DNA-helicase	unknown	unknown	gnl\|CDD\|273206
NC_011835.1\|WP_004218496.1\|223301_223640_+\|P-II-family-nitrogen-regulator	unknown	unknown	gnl\|CDD\|366157
NC_011835.1\|WP_004218484.1\|210636_211377_+\|energy-coupling-factor-transporter-transmembrane-protein-EcfT	unknown	unknown	gnl\|CDD\|223692
NC_011835.1\|WP_004268977.1\|217750_219319_+\|C69-family-dipeptidase	unknown	unknown	gnl\|CDD\|335383
NC_011835.1\|WP_004218486.1\|212966_214550_-\|ZinT/AdcA-family-metal-binding-protein	unknown	unknown	gnl\|CDD\|370371
NC_011835.1\|WP_004218501.1\|229521_230271_+\|glutamine-amidotransferase	unknown	unknown	gnl\|CDD\|225974
NC_011835.1\|WP_004218488.1\|214745_215627_-\|patatin-family-protein	unknown	unknown	gnl\|CDD\|132847
NC_011835.1\|WP_004218495.1\|222004_223300_+\|ammonium-transporter	unknown	unknown	gnl\|CDD\|223083
NC_011835.1\|WP_004218497.1\|223950_225777_+\|nucleotidyltransferase-domain-containing-protein	unknown	unknown	gnl\|CDD\|235123
NC_011835.1\|WP_004218503.1\|230834_232985_+\|AarF/ABC1/UbiB-kinase-family-protein	unknown	unknown	gnl\|CDD\|223733
NC_011835.1\|WP_004218481.1\|204741_206940_-\|YhgE/Pip-domain-containing-protein	unknown	unknown	gnl\|CDD\|224428
NC_011835.1\|WP_004218485.1\|211429_212917_+\|ATP-binding-cassette-domain-containing-protein	unknown	unknown	gnl\|CDD\|213193
NC_011835.1\|WP_004218494.1\|220344_221745_+\|signal-recognition-particle-docking-protein-FtsY	unknown	unknown	gnl\|CDD\|236686
NC_011835.1\|WP_004218491.1\|216709_217420_-\|hypothetical-protein	unknown	unknown	unknown
NC_011835.1\|WP_004218483.1\|209998_210640_+\|MptD-family-putative-ECF-transporter-S-component	unknown	unknown	gnl\|CDD\|370580
NC_011835.1\|WP_004218498.1\|226137_226410_+\|helix-turn-helix-transcriptional-regulator	unknown	unknown	gnl\|CDD\|238045
NC_011835.1\|WP_004218502.1\|230378_230726_+\|phasin-family-protein	unknown	unknown	gnl\|CDD\|226447
NC_011835.1\|WP_004218489.1\|215762_216530_+\|hypothetical-protein	unknown	unknown	unknown
NC_011835.1\|WP_004218482.1\|206936_209705_-\|YhgE/Pip-domain-containing-protein	unknown	unknown	gnl\|CDD\|224428
NC_011835.1\|WP_004218500.1\|227944_229453_+\|Mur-ligase-family-protein	unknown	unknown	gnl\|CDD\|377986

Protein	Function_ID	Function_description	E-value
NC_011835.1\|WP_004218499.1\|226468_227848_+\|replicative-DNA-helicase	gnl\|CDD\|273206	TIGR00665, DnaB, replicative DNA helicase. This model describes the helicase DnaB, a homohexameric protein required for DNA replication. The homohexamer can form a ring around a single strand of DNA near a replication fork. An intein of > 400 residues is found at a conserved location in DnaB of Synechocystis PCC6803, Rhodothermus marinus (both experimentally confirmed), and Mycobacterium tuberculosis. The intein removes itself by a self-splicing reaction. The seed alignment contains inteins so that the model built from the seed alignment will model a low cost at common intein insertion sites. [DNA metabolism, DNA replication, recombination, and repair].	0
NC_011835.1\|WP_004218484.1\|210636_211377_+\|energy-coupling-factor-transporter-transmembrane-protein-EcfT	gnl\|CDD\|223692	COG0619, CbiQ, ABC-type cobalt transport system, permease component CbiQ and related transporters [Inorganic ion transport and metabolism].	8.57319e-16
NC_011835.1\|WP_004268977.1\|217750_219319_+\|C69-family-dipeptidase	gnl\|CDD\|335383	pfam03577, Peptidase_C69, Peptidase family C69.	0
NC_011835.1\|WP_004218486.1\|212966_214550_-\|ZinT/AdcA-family-metal-binding-protein	gnl\|CDD\|370371	pfam09223, ZinT, ZinT (YodA) periplasmic lipocalin-like zinc-recruitment. ZinT plays a critical role in recruiting periplasmic zinc to the bacterial zinc-uptake complex ZnuABC, consisting of families pfam01297,pfam00950, pfam00005, regulated by the transcription-regulator FUR, pfam01475. ZinT acts as a Zn2+-buffering protein that delivers Zn2+ to ZnuA (TroA), pfam01297. Members of this family of prokaryotic domains were first identified as part of the response of bacteria to a challenge with the toxic heavy metal cadmium. They are able to bind to cadmium, and ensure its subsequent elimination.	2.36038e-102
NC_011835.1\|WP_004218501.1\|229521_230271_+\|glutamine-amidotransferase	gnl\|CDD\|225974	COG3442, COG3442, Predicted glutamine amidotransferase [General function prediction only].	6.70842e-71
NC_011835.1\|WP_004218488.1\|214745_215627_-\|patatin-family-protein	gnl\|CDD\|132847	cd07208, Pat_hypo_Ecoli_yjju_like, Hypothetical patatin similar to yjju protein of Escherichia coli. Patatin-like phospholipase similar to yjju protein of Escherichia coli. This family predominantly consists of bacterial patatin glycoproteins, and some representatives from eukaryotes and archaea. The patatin protein accounts for up to 40% of the total soluble protein in potato tubers. Patatin is a storage protein, but it also has the enzymatic activity of a lipid acyl hydrolase, catalyzing the cleavage of fatty acids from membrane lipids. Members of this family have also been found in vertebrates.	1.81216e-110
NC_011835.1\|WP_004218496.1\|223301_223640_+\|P-II-family-nitrogen-regulator	gnl\|CDD\|366157	pfam00543, P-II, Nitrogen regulatory protein P-II. P-II modulates the activity of glutamine synthetase.	1.87627e-50
NC_011835.1\|WP_004218497.1\|223950_225777_+\|nucleotidyltransferase-domain-containing-protein	gnl\|CDD\|235123	PRK03381, PRK03381, PII uridylyl-transferase; Provisional.	2.75736e-140
NC_011835.1\|WP_004218503.1\|230834_232985_+\|AarF/ABC1/UbiB-kinase-family-protein	gnl\|CDD\|223733	COG0661, AarF, Predicted unusual protein kinase [General function prediction only].	9.00342e-109
NC_011835.1\|WP_004218481.1\|204741_206940_-\|YhgE/Pip-domain-containing-protein	gnl\|CDD\|224428	COG1511, COG1511, Predicted membrane protein [Function unknown].	3.31235e-80
NC_011835.1\|WP_004218485.1\|211429_212917_+\|ATP-binding-cassette-domain-containing-protein	gnl\|CDD\|213193	cd03226, ABC_cobalt_CbiO_domain2, Second domain of the ATP-binding cassette component of cobalt transport system. Domain II of the ABC component of a cobalt transport family found in bacteria, archaea, and eukaryota. The transition metal cobalt is an essential component of many enzymes and must be transported into cells in appropriate amounts when needed. The CbiMNQO family ABC transport system is involved in cobalt transport in association with the cobalamin (vitamin B12) biosynthetic pathways. Most cobalt (Cbi) transport systems possess a separate CbiN component, the cobalt-binding periplasmic protein, and they are encoded by the conserved gene cluster cbiMNQO. Both the CbiM and CbiQ proteins are integral cytoplasmic membrane proteins, and the CbiO protein has the linker peptide and the Walker A and B motifs commonly found in the ATPase components of the ABC-type transport systems.	9.80258e-74
NC_011835.1\|WP_004218494.1\|220344_221745_+\|signal-recognition-particle-docking-protein-FtsY	gnl\|CDD\|236686	PRK10416, PRK10416, signal recognition particle-docking protein FtsY; Provisional.	1.18657e-157
NC_011835.1\|WP_004218495.1\|222004_223300_+\|ammonium-transporter	gnl\|CDD\|223083	COG0004, AmtB, Ammonia permease [Inorganic ion transport and metabolism].	6.64221e-146
NC_011835.1\|WP_004218483.1\|209998_210640_+\|MptD-family-putative-ECF-transporter-S-component	gnl\|CDD\|370580	pfam09605, Trep_Strep, Hypothetical bacterial integral membrane protein (Trep_Strep). This family consists of strongly hydrophobic proteins about 190 amino acids in length with a strongly basic motif near the C-terminus. It is found in rather few species, but in paralogous families of 12 members in the oral pathogenic spirochaete Treponema denticola and 2 in Streptococcus pneumoniae R6.	3.6075e-52
NC_011835.1\|WP_004218498.1\|226137_226410_+\|helix-turn-helix-transcriptional-regulator	gnl\|CDD\|238045	cd00093, HTH_XRE, Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators.	9.90477e-14
NC_011835.1\|WP_004218502.1\|230378_230726_+\|phasin-family-protein	gnl\|CDD\|226447	COG3937, COG3937, Uncharacterized conserved protein [Function unknown].	7.70598e-09
NC_011835.1\|WP_004218482.1\|206936_209705_-\|YhgE/Pip-domain-containing-protein	gnl\|CDD\|224428	COG1511, COG1511, Predicted membrane protein [Function unknown].	3.59495e-89
NC_011835.1\|WP_004218500.1\|227944_229453_+\|Mur-ligase-family-protein	gnl\|CDD\|377986	pfam08353, DUF1727, Domain of unknown function (DUF1727). This domain of unknown function is found at the C-terminus of bacterial proteins which include UDP-N-acetylmuramyl tripeptide synthase and the related Mur ligase.	9.03252e-41

>NC_011835.1|WP_004268977.1|217750_219319_+|C69-family-dipeptidase
MSCTTLLVGKSASYDGSTIIARNDDSGSGTYDPKKFVAVRPEDQPRHYRSVISHMEIDLPGDPCLYSIVPNVRPNRGVLAEAGVNEHNVAMSATETIAVNSRVLAADPLVKLVPAHGEPGDADYREEVPGGFGEEDIITLVLPYVRTAREAVARIGELLATYGTYESNGIIASDVDEIWYVETIGGHHWIARRVPDDCYAAIPNQLGIDLLDIDDAMSECRNNMCSADLADFIEANHLDRAMPDPEFANHTAQHINPRTVFGTATPKDAIYNTPRAWYMQRHLNPSDDWDSPAAQYRPDSQDMPWAREPESKVTIEDVAFLMGSHFQGTPFDPYGTTGTAESRHRYRPIGVNRTGQMVCMQIRPYAPAAYRSIMWVSYGSGAFTTPAPFYANVTDTPAYLRDTDGENASTNSLYWTNRILAVMADAHYYDTDGEIEQYIEDVQAHGHRLVADTDASIRADADALASDSAHEGLKAVRLELETANKAMADWLQMRTQTLLNQVLYTTSNLMHNAFKMSDHWMS
>NC_011835.1|WP_004218491.1|216709_217420_-|hypothetical-protein
MAQHDNTNTEIIRPQGGSQTQAAADTAQIAHTQADAPTQPQGYAFDFAQQQGEQIPPSQGYAPQNGEQPFTTAANTAQPNMGGNGVPNNPQGGQMPMNGGAPGNRGTATLRGKPGGKTIGIIAAISLGCGLVAGIAGTAVTNAIYRSNEPSHSNMMMRGIGDRGFGEGDGDGESMPDFGSGNGSRNRRSYRADGQMPGMQDSDGANGESNGDARNRSQSNDSDSNADSGSSDSSKN
>NC_011835.1|WP_004218489.1|215762_216530_+|hypothetical-protein
MLVPMNDVNPYAAAAHIEVLPLTPTRQSIERALVEWMTQTGRPASDLSVSALCKKAFVARSTFYANYRHMGQVYESVENRLLRQLFECAVPMRVRADGTDETMRSFNAFVKVLHAHENEFRLVLVRQPSSRFVALWKQSLEYHVWHRLFETERGGAAAVDAVAEWGDGAAPGTSNGGSATSQEGLPAGTDADATNRNELPVRQGPATVNRALVFDMAATAFIAGVTFWLRTPQAVSLPEIRASVVKLVNNIDEIW
>NC_011835.1|WP_004218488.1|214745_215627_-|patatin-family-protein
MAVQQTTQPTRPTRREKVGVIDVGGGLRSAYSTGVLDYCLDNGIHFDYGLGVSAGAANITSYLAGQRGRPLRFYTKYCPRPEYMSLGNFLRDGSYLGLDYIYGTLMNEDGEDPLDYDALVAGGVPYRITVTDALSGMPKYLGPESMSRNHYDALKATACLPVLDKPYPLDGRPYFDGTISDPIPFRQAFADGCTKLVVILTRPRDFYRNPDKDIASSMMLAVRYPEAARALANRAHTYNVELNMCKRLEAQGKVRIIAPKSIDGVSTLTKDPDKIQNLYNRAYNDATALRNFL
>NC_011835.1|WP_004218486.1|212966_214550_-|ZinT/AdcA-family-metal-binding-protein
MTEQSTNQRSATHDEPRRRPITRTAIAFLAGLAVCGLAASTLSGCGNNAGENRTSAAAARQTTDSCDTTINVVASVNQWGSLAQQLGGSCVNVTSIINSTAADPHDHEATPADLTKLARADVVVLNGAGYDGWAQKAQLDEGRQRIVKASSLMGIADSQDDHDHEEGEGHHHHHGTVNPHLWFSPAAVLKMSEAITSAYVTKSGEASETAATARRHSNTWNAEYAEYTALVNRARAKNLQRRYVATESIIGHLLDYIGATDKTPDSYTNAMNNDAEPSASDLKNALDTVGSSNVDMLIVNPQEMGGFAKKLDAAARESGKTIISVTEQLPENHKTLLGWLTTITNQALADDPQHGWFLTQQVKDRTIADYAGQWRSVYPLLKNGKLRGVMEHKAATGDKTADEYTAYYDAGYKTDTETITIEGDRMAFTTNGRKVTATYRYDGHRILDYAKGNRGVRYLFTATGDVPQGAPKAVQFSDHGIAPGKAAHFHIFTGDSHDEVIKQMEHWPTYYPASMSDDEIVKEMLAH
>NC_011835.1|WP_004218485.1|211429_212917_+|ATP-binding-cassette-domain-containing-protein
MNGTRCALDGCSFRYASDESADGVERGVHAIDHVSLQARAGEVVMLVGRSGCGKTTVTRLLNGLAPEYFRGSLHGEARVGGLHAGVAAVEDYATEVGSVFQNPKTQYFHANSTDELAFPCENAGMEPSEIRRRIRERLRAFDVEHLHDRNIVDCSGGQQQQLAVVAATMLDPGVLVLDEPTSNLDAEAMERLRNMVKRLKRDGIAIVIAEHRLAWVADLADRYVVFDAGRVVGEYTAEQFHALPESQRRAWGLRALELSGPRGQVERIAQRAEPSGEKPVIATRGLKVGYERRRLFGRTKRGFVREVGDVNLFAGQIVGLIGRNGAGKSTFVKTVCGLVEPVAGEILVDGRAAKPGRLSALCAMVMQDVNYQLFASSVREEMLLEAMQHVRTAEDAQRVRERADGILRQLGLLDFAERHPMTLSGGQKQRLAIGVALMGEKRVVVLDEPTSGLDRHHMLQVGALMRDLADRGVCVLVVTHDDELAAEVCDRIVRF
>NC_011835.1|WP_004218484.1|210636_211377_+|energy-coupling-factor-transporter-transmembrane-protein-EcfT
MTEVVVPRETRVPIRATRGVLHFDPRVKLAMLVVANMMMFLHVGPYAGMMGVLLFSLPMLCGGKIALGMGMLACYAMCLGVDWLAAAVADAAPWLHVPGALAAGGAMMLPCLIAGMSAFATTPPGELVAALRRLHLPDAVVIPAIVLLRFFPTIARDYRMIRCSMRLRGINVGGWAMLCHPMRSLEYVLVPLLMNAANAAHDLTVSALTKGLGRRRATSSSAMLHMQAIDWAMLALCCLPLIPWQA
>NC_011835.1|WP_004218483.1|209998_210640_+|MptD-family-putative-ECF-transporter-S-component
MSDMERDARRREVRAAGGTRLTVADLINVGVFGAVYFALVGVAALASMAVFGVAGNILLPAIAAVLAGPVFMLMVARVRRFGAITLMGLMLGLFLFVSGHFATSLVTAIVFPLAADCIARFGAWRRPWALMLSYVVFSFGCTGPILPLWMMKDAYIASLERKGKDAAYIDALFGAVNGTTFVVAMVAIVIGALVGGLFGMRLMRRHFLKAAVA
>NC_011835.1|WP_004218482.1|206936_209705_-|YhgE/Pip-domain-containing-protein
MRNIWFILRRDLKRLIINPAAWVIIFGLTFIPALYAWFNIIGFWNPYGNTKGITVAVANEDAGADNAMMGKLELGDQIESTLKENHELGWTFLGKAKAMECVESGHCYAAIVIPRNFSENMAAVITGSGQRPTLEYYVNEKVNAVAPKMTDVGANTVDRQVNSAFVSTVSKAVTDTINTTNVQITQEGNATVAQTVAKLDATKANLSKSRTMIADLRKTLDGVDEKTTAAKQALAGVDSAATSASQGLTSASGLLTKTQGGITSFSNDLSTELDQGGNLFLQASGKASTSATRVANGVLTASGATGSALNELTSVNKTNAQILADLKALPDNPLSEQINEIVTDLSAENEKVAQTLQTLTTLNDSTTAAANSTLGTVDQFSATSTTTVDALSGARNTINSSAIPQLNSGLATLSGTAGTLSGFLTGTQSLTGQTNLILDQLTQICQSTSSSLNSTDDLLGKFITRIDTVTTDLKTLENTNVLSDLLGSKNGTLDASRIASFMLSPTVLDTHTLYPIDTYGSGMAPLFTSLALWVGVFMLMVLFKLEVDNEGLEGRHVTTNQTYMARYLLLAIVAGLQGIVCAVGDLIIRVQCANRFVFILTAWLTSLAYLAIAYALSATFMHVGKALVVALVMLQIPGASGLYPIEMMPDFYRALYPFFPFTYSINAFRETIAGFYDGDWLTKMLMLALFTAIAFFVGLVVRPWLGNFNHLFAREVHEGDMIVGERVYMPANRFDLAQALHVLADHGEYRRRIERRAKRFATLYPRLMRGALVAGFAVPIVLFIVFSFVGASDGSKLVALATWIAWILIIIIFLMTVESIRESLRRQTELGSLSEDSLRDMIMAQGVFGNNRHHITVPADELRPDAASNSRERAEKRREERDLNHREDTLDLNLNELRKPERQRKHRGSTSRRNHHDGRHSA
>NC_011835.1|WP_004218481.1|204741_206940_-|YhgE/Pip-domain-containing-protein
MSMLAKIFADDVRHLTSNIVSIIITIGLIVIPGLFTWFNVAACWDPFANTKNLQFAIANDDEGYKGDLLPMRINIGEQVVDTLRANSQLDWTFTKSSAEAIDGTKSGKYYAAVVIPKNFSKNMMTFFTDDAYHATLDYYNNEKLNALAPKVTGQGADTIAATINQTFSKTLTDTALNLASSMLDMLDKPEYQQRLKSFNGNIADLAGMLNDSAAVLRTYSSLTDSAKTLLASSNKLIADARASAKTGVDDLSAAKTGVSDLSGALGTSVNALGTAIDTSKTSLGSLNDRVDELFSAVDKQAGDTSAAINNLAGNVRTEATAYATTRGRLQELLDKSDNLGPVAKSAVQAFINRIGAVADDLNQTADRLTTAANDVDSKVGSSKETRQEIKDLAGKAQSSVSSISKDFDETIKPDLTAMTNAFSDAANSLNGTVSTLDSSLDSLSGTASDANKQLDSVHELIDNAATQLTDAAKELTNFNTQFAKALDTGNMGTIKKLLSGNTATLSTALSTPVELKRVALFPVDTFGAALTPFYTFLPLWVGALLLVVTLKIGISRKRQRELGNPKPWQIFLGHYGVFVSIALLQSTFSCAGTLLFLRVQVVHPWLFMLVGWFSSIVYSFFTYTLVSTFANVGKAIGVLFLVMQISGSNAAYPLSILPHFISDISPWLPVSYSVTAMRGAIAGIYENDYWIAMGKLALFLVPLLFIGLVLRHALLGFNHWYEARVERTKLLG
>NC_011835.1|WP_004218494.1|220344_221745_+|signal-recognition-particle-docking-protein-FtsY
MDTNTIYAIVIIAVIAVALIIGSWLIGRSRRNAINKSTEHAKAAADARLAAERAQAEQEEREAHEQAKEPAESGARQSSGGKPAEPTNEEKIEAEEPAISRAELEAQERERLSQTPPKLAAAEEVPGEESAQAESVVEDLAVVDEVPTPPAEQIEKPAGKKSRLQRLRERLSKSSNPFGKALFNILAKDQLSEADWEDVEDTLLLADVGAEASEELVDKLRTDARVTGESDPRQLRDALRSELLALVGPDMDRTLEAEKPDAKKPSVIIMVGVNGTGKTTTAGKLARLFVSEDKTVLLGAADTFRAAAADQLETWGAKVDVPVVRSDREGADPASVAFEASAKAKELGTDVLIIDTAGRLQNKANLMDELGKIRRVAEKNLPVDEVLLVLDATTGQNGMAQAKVFAEAIGITGVVLTKLDGSAKGGIVISVQKELGVPVKLVGVGEGPDDLAPFDPESFVDGILGE
>NC_011835.1|WP_004218495.1|222004_223300_+|ammonium-transporter
MSQLDSGNAAWILTSACLVFLMTPGVALFYGGMVRAKAVLNMLIMEAAALSVTMIIWGLWGWSIAYAGNSIGGVFGDPATGFLLRDTMVAQDGVFTSASLNSNNYPASVDVAFQAAFAMITVALICGAIAERVKYSTWMIFVALWITFDYAPMAHMVWNGGLLSADGAISQALGAAAHDFAGGTVVHINAAVAALIIVLIIGKRKGFGVEPMRPHNVPFVMLGAFLLWFGWFGFNAGSAFAANGVAGYAWVSTSLAAAAAMLTWGFTEKIRTGHYTAMGAASGIVAGLVAITPAADVVSPIWAIVLGAIAGVVTCLACSLKFKLGYDDSLDVVGVHGVGGLVGTVLLGFFMEGTGLFYSGKWNQLGVQLIIAIIAIAFSAVITTIIAFALEKTIGWRVTQAQEVAGIDLADQGERAYDFAGTASSVIREMK
>NC_011835.1|WP_004218496.1|223301_223640_+|P-II-family-nitrogen-regulator
MKLITAIIQPHKLDDVKEALASAGVHGLTVSEANGYGRQRGHTEIYRGAEYTVDLIPKVRVEVLSDDADAETLVDVIVKSAGSGTIGDGKVWVAPLDMVVRVRTGETGSAAI
>NC_011835.1|WP_004218497.1|223950_225777_+|nucleotidyltransferase-domain-containing-protein
MAMSTLKQQFLELSEPDADGVYRNGSAKRMARTNLAMRELEALWNEAVHSVPFQIPDSGIGLAAVGSLARGQIGPASDLDLVLITADHVALSTTQLNEFANKLWYPIWDSGLDLDHSVRTVSRCESVTDHDLPAAMGWLNVNPIAGDRHLIETTATAILERWRKAARKRLPELLESANVRNERFDRMSYVNQPDIKESRGGLRDTVLLSALAASWLADRPHGRYDDAVERLLDVRDAIHLITRKDADRLLTQYQAEVAAMLGLTDPTLPEGEREAKSIDDLQTLLASLSRTIAFALDSTASRAQRTLVHDKPRFSFFQILSPRAGGKREAPKFEMLAPGVAKHEQEIVLAPQADPLADPALPLRVAAAAGREGLPINTSTLVNLKRAPIHDKAWSDEMRRLFVELLASGERLPQVWEELDFVGIPGRLMPEWDAIRNRPSVSAAHRYTIDRHMLAVTAQLGRERPVNGGAFDDVHYTALLLAGILHDIGKRPGVADHAAEGARHAAVIVRRMGFDDQMVDWVRLLVREHLTLSDFASSRNPNDPEVGAELASLVDGDPQLLDMLFALTKADMSSLGATAGETISNTVGWSKWRARLVTQMAALARASM
>NC_011835.1|WP_004218498.1|226137_226410_+|helix-turn-helix-transcriptional-regulator
MRSFNSMLDEQMDDPEFATVFEAEIERLNAAVAVSRAREEARLTQEQLAERSGVSRVTINRIERGKLNPSMKTLSRLARAMGKQVRVSIS
>NC_011835.1|WP_004218499.1|226468_227848_+|replicative-DNA-helicase
MADGFHNNTRTDTSANAAGLFDRVPPHDDNAEMATLGGMLMSKDAIGEVSQIVSVDDFYEPKHQTIYEAIIGKFSASEPADAVTVANRLSDSGDLDKVGGIDYLHSLIASVPTAANASYYAEIVHQRALLRRVIASGTKIAQLGYDAEGSQAQDVINMAQAEVYEMSTGRVRQDYAPVQAAVHDALDQIDSIQKGELQAGVPTGFQEIDEVTKGLQPGQMVVVAGRPAMGKSTLGVDFARSAAIHHHDTTILFSLEMSKVELAQRIISAETGVPLAALRNADDIDPNRWNTLNNFYARLQDAPLFIDDSPNMSLMEIRAKCRRLKQTNDLKLVVIDYLQLMTSGKAVESRQQEVSEFSRALKLLAKELEVPVVALSQLNRGPEMRNDKKPQLSDLRESGSIEQDADVVFLVHRPDFYDEEDRPGEADIIMAKHRNGPTRTFGLVFQGQYSRFSDMNREV
>NC_011835.1|WP_004218500.1|227944_229453_+|Mur-ligase-family-protein
MADSGTSNANPVRTHAPWYGFATPFVGKSVRWASRLLHHGGSAFPGKVVERFDPTFLSRTLSTLPLGVVLVSGTNGKTTTTRMVATMLESLGLKVFTNPTGSNFTRGVVSSILTEVPLNGRLDADIAVLELDEAYAVHFVEQVQPRYALLLNVMRDQLDRFGEIDNTARLLGHVAAATRGTVVLNREDPRIARLRDVVKDGVRTRYFGLAEGLRHYFPADDDMTTTFQVQSADSAQAPEAADAQIVDVAHDVGTAHELHADVMLTKVGDHHAQMVIDGREYESDVKLEGVYNLFNAAAALAVVRAVQADLRKPNAVGYAAAQLGRADSARARAFTARAHTFADADTDALFAALADVTPAFGRGEVIDVNGSPVELLLVKNPMGFRLALASFPPESADTMIAINDQYADGRDMSWLWDVDFTSLRPTGVAMVSGVRAWDMALRLEYDQVPVARVEPDLNAAVREFVNANPGTPKHIYCTYTAMLAIRAELATVADVADAGVGK
>NC_011835.1|WP_004218501.1|229521_230271_+|glutamine-amidotransferase
MSKAIDVVSLYPKDMNIYGDSGNVLAVERRLALYGYEPHVHAVNQNDPWPEHADIILGGGGQDTGQKKIIEDLFRRADRLRDLAEHGVPMLMICGLYQLFGEYFETIDGTKLEGISIIRAYTVGRDVRMIGNLVEHSAQFGDVLGYENHSGQTFLREGVQPLGTVDGDGTGNNGEDHTEGARVHNVIGTYMHGSLLPKNPKITDFMIRTAVERRYGAFDPEQTDAQRAELARIDEYAAHAREAAATRPR
>NC_011835.1|WP_004218502.1|230378_230726_+|phasin-family-protein
MTDETKNETENKTNSAMPDFGEGLRKVFLAGVGAIAATAEKGQELVNDLVKRGELTVEQGKKLNSELAHKAGEKSDSLKEKLADASNTVRNAAAGLSDQAEQTIKKATEKKSDEQ
>NC_011835.1|WP_004218503.1|230834_232985_+|AarF/ABC1/UbiB-kinase-family-protein
MSDKNSDKSKRETEAHELRRDVRREEAGQRRQQRKDACEARHLEHEEKRETSELIDLSNRLENQEAHSDGPAFDNPTDDALRATVETAESEKILHLGDEVDEQGATIEHNLQREEAEQSGGEASETAAQPETPAPQSAQSERPADAHTHDIPASIARRQQPQVEETIGLFGMHKRNFSSEYHLTRMSKAKRLKQIGKIALEYDALHGLTPVKMRLMFEALGPTFVKVGQILSMRSEILPESFCAELSKLRADADPMPYAIVLGTLENEYQRPIDEIFEHIDTTPLGSASLAQVHRATLKTGEDVAVKVQRPGVRETMAQDVSIMRSLAKGATKIMHSSQVVDFRGVVEELWETFDEETNFLNEARNLAEFKRFCSHYAYMDCPTPFTDLCTEHVLVMQYIDGIPISHTRELIDDGYSLNEIGTKLVDNYAAQILDAGFFHADPHPGNIEIRGGKIILLDLGMTGRLDARTRVALKQMLFAVAKQNSADLADALLRFAGTDVERADYPSLLGDLDGIVEEFGTVDLADLDLAAFITSLTQMARRHGIEIPSSVTTVGRALVTLEGLLDEFIPNVNMIEIISQHIESSKTPVEMVKSEVKRLGIESEQALHSGLKGIVDAQTALHMLTRGELKMNLELVGSEEPLSQMSDMVNRLTMALIVVGLFIGSSIVYFAGMKPIIFGIPVVGFLGYVAAFVLSVWIVIDILIKRHAAKHKARK

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Crispr_ID: NC_011835_3

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_011835_3

642758-644162

Unclear

Consensus_repeat	Method
CCCTCAATGAAGCTCCGAAGCCGAGACTTCGGAGAT	CRISPRCasFinder
CCCTCAATGAAGCTCCGAAGCCGAGACTTCGGAGAT	CRT
CCCTCAATGAAGCTCCGAAGCCGAGACTTCGGAGAT	PILER-CR

19 spacers

cas1,cas2,cas7,cas3,csb3

The CRISPR arrays of NC_011835_3

>merge|NC_011835|3|642758-644162|CRISPRCasFinder,CRT,PILER-CR
TCCTCAATGAAGCTCCGAAGCCAAAACTTCGGAGATGCCTCCTGATGGATCTCCACGACGTTGCTGGCCCTTCCTCAATGAAGCTCCGAAGCCGAGACTTCGGAGATGCCATCCCGACTGTGGCGGCGGCGTTCGGTGTCGCCCCTCAATGAAGCTCCGAAGCCGAGACTTCGGAGATGACAGTGCGAACACAGTGCAGTCGGTGACGATCGCGCCCTCAATGAAGCTCCGAAGCCGAGACTTCGGAGATTCGGTCTTCTTGAGCTGGTCGGTGAGTGTCTTGAGCCCCTCAATGAAGCTCCGAAGCCGAGACTTCGGAGATGCAACGCCTTCGTTCGCCTCGTGGACTATCGCGGCCCCCTCAATGAAGCTCCGAAGCCGAGACTTCGGAGATCAGGTTCTCGAGGATGCTCACTATTTCCGTGAGGATGATCCCTCAATGAAGCTCCGAAGCCGAGACTTCGGAGATCTATACCCGTATGCAATGCTGTGCGCGTTGGATGCAAGCCCTCAATGAAGCTCCGAAGCCGAGACTTCGGAGATTGGCGCGAGCAGTATCACCACGTGGCTGCTCAACCGCCCTCAATGAAGCTCCGAAGCCGAGACTTCGGAGATAACGGTTCGATGGTTCGCACAGTGAGTTGTTCACTCCCCTCAATGAAGCTCCGAAGCCGAGACTTCGGAGATTTCGTCTCCTCCCTGCGCCGCTGATTGACCTGTTTCCCTCAATGAAGCTCCGAAGCCGAGACTTCGGAGATATTTCAGGCGGCATCAGACCTTGCGGCTGGGATTCCCTCAATGAAGCTCCGAAGCCGAGACTTCGGAGATGCGTGTGGTGGAAAAACCAGCCCGTCACCGAAGCGGCCCCCTCAATGAAGCTCCGAAGCCGAGACTTCGGAGATTCGCAGGTGAATATCGGTGGCGGCGGCTTGTCGTCCCTCAATGAAGCTCCGAAGCCGAGACTTCGGAGATCGGATAGTATCCTGCGTCGCGTCTCCAATGGCGACCCTCAATGAAGCTCCGAAGCCGAGACTTCGGAGATCTGACAGCATCCTCTCATTCCTCTCGAACGGCGAATACCCCTCAATGAAGCTCCGAAGCCGAGACTTCGGAGATTGTTCGCTTTGATGCGTGTGATTGAGTTCGGCTTCCCTCAATGAAGCTCCGAAGCCGAGACTTCGGAGATTTCGGCGCGTGTTCCTCCGCCGTTGCCGTTGTGGTGGGCCCCTCAATGAAGCTCCGAAGCCGAGACTTCGGAGATGAGGTCATGGTGAAGTCGCGTTCGGTGCCGGTCTTCCCTCAATGAAGCTCCGAAGCCGAGACTTCGGAGATCCGCCTCCCACTCCGCCACGCTGAGCGCCATATCGTCCCCTCAATGAAGCTCCGAAGCCGAGACTTCGGAGAT

>NC_011835|3|3|642758-644162|CRISPRCasFinder
TCCTCAATGAAGCTCCGAAGCCAAAACTTCGGAGAT	GCCTCCTGATGGATCTCCACGACGTTGCTGGCCCT
TCCTCAATGAAGCTCCGAAGCCGAGACTTCGGAGAT	GCCATCCCGACTGTGGCGGCGGCGTTCGGTGTCGC
CCCTCAATGAAGCTCCGAAGCCGAGACTTCGGAGAT	GACAGTGCGAACACAGTGCAGTCGGTGACGATCGCG
CCCTCAATGAAGCTCCGAAGCCGAGACTTCGGAGAT	TCGGTCTTCTTGAGCTGGTCGGTGAGTGTCTTGAGC
CCCTCAATGAAGCTCCGAAGCCGAGACTTCGGAGAT	GCAACGCCTTCGTTCGCCTCGTGGACTATCGCGGCC
CCCTCAATGAAGCTCCGAAGCCGAGACTTCGGAGAT	CAGGTTCTCGAGGATGCTCACTATTTCCGTGAGGATGAT
CCCTCAATGAAGCTCCGAAGCCGAGACTTCGGAGAT	CTATACCCGTATGCAATGCTGTGCGCGTTGGATGCAAG
CCCTCAATGAAGCTCCGAAGCCGAGACTTCGGAGAT	TGGCGCGAGCAGTATCACCACGTGGCTGCTCAACCG
CCCTCAATGAAGCTCCGAAGCCGAGACTTCGGAGAT	AACGGTTCGATGGTTCGCACAGTGAGTTGTTCACTC
CCCTCAATGAAGCTCCGAAGCCGAGACTTCGGAGAT	TTCGTCTCCTCCCTGCGCCGCTGATTGACCTGTTT
CCCTCAATGAAGCTCCGAAGCCGAGACTTCGGAGAT	ATTTCAGGCGGCATCAGACCTTGCGGCTGGGATT
CCCTCAATGAAGCTCCGAAGCCGAGACTTCGGAGAT	GCGTGTGGTGGAAAAACCAGCCCGTCACCGAAGCGGCC
CCCTCAATGAAGCTCCGAAGCCGAGACTTCGGAGAT	TCGCAGGTGAATATCGGTGGCGGCGGCTTGTCGT
CCCTCAATGAAGCTCCGAAGCCGAGACTTCGGAGAT	CGGATAGTATCCTGCGTCGCGTCTCCAATGGCGA
CCCTCAATGAAGCTCCGAAGCCGAGACTTCGGAGAT	CTGACAGCATCCTCTCATTCCTCTCGAACGGCGAATAC
CCCTCAATGAAGCTCCGAAGCCGAGACTTCGGAGAT	TGTTCGCTTTGATGCGTGTGATTGAGTTCGGCTT
CCCTCAATGAAGCTCCGAAGCCGAGACTTCGGAGAT	TTCGGCGCGTGTTCCTCCGCCGTTGCCGTTGTGGTGGGC
CCCTCAATGAAGCTCCGAAGCCGAGACTTCGGAGAT	GAGGTCATGGTGAAGTCGCGTTCGGTGCCGGTCTT
CCCTCAATGAAGCTCCGAAGCCGAGACTTCGGAGAT	CCGCCTCCCACTCCGCCACGCTGAGCGCCATATCGTC
CCCTCAATGAAGCTCCGAAGCCGAGACTTCGGAGAT

>NC_011835|3|1|642758-644162|CRT
TCCTCAATGAAGCTCCGAAGCCAAAACTTCGGAGAT	GCCTCCTGATGGATCTCCACGACGTTGCTGGCCCT
TCCTCAATGAAGCTCCGAAGCCGAGACTTCGGAGAT	GCCATCCCGACTGTGGCGGCGGCGTTCGGTGTCGC
CCCTCAATGAAGCTCCGAAGCCGAGACTTCGGAGAT	GACAGTGCGAACACAGTGCAGTCGGTGACGATCGCG
CCCTCAATGAAGCTCCGAAGCCGAGACTTCGGAGAT	TCGGTCTTCTTGAGCTGGTCGGTGAGTGTCTTGAGC
CCCTCAATGAAGCTCCGAAGCCGAGACTTCGGAGAT	GCAACGCCTTCGTTCGCCTCGTGGACTATCGCGGCC
CCCTCAATGAAGCTCCGAAGCCGAGACTTCGGAGAT	CAGGTTCTCGAGGATGCTCACTATTTCCGTGAGGATGAT
CCCTCAATGAAGCTCCGAAGCCGAGACTTCGGAGAT	CTATACCCGTATGCAATGCTGTGCGCGTTGGATGCAAG
CCCTCAATGAAGCTCCGAAGCCGAGACTTCGGAGAT	TGGCGCGAGCAGTATCACCACGTGGCTGCTCAACCG
CCCTCAATGAAGCTCCGAAGCCGAGACTTCGGAGAT	AACGGTTCGATGGTTCGCACAGTGAGTTGTTCACTC
CCCTCAATGAAGCTCCGAAGCCGAGACTTCGGAGAT	TTCGTCTCCTCCCTGCGCCGCTGATTGACCTGTTT
CCCTCAATGAAGCTCCGAAGCCGAGACTTCGGAGAT	ATTTCAGGCGGCATCAGACCTTGCGGCTGGGATT
CCCTCAATGAAGCTCCGAAGCCGAGACTTCGGAGAT	GCGTGTGGTGGAAAAACCAGCCCGTCACCGAAGCGGCC
CCCTCAATGAAGCTCCGAAGCCGAGACTTCGGAGAT	TCGCAGGTGAATATCGGTGGCGGCGGCTTGTCGT
CCCTCAATGAAGCTCCGAAGCCGAGACTTCGGAGAT	CGGATAGTATCCTGCGTCGCGTCTCCAATGGCGA
CCCTCAATGAAGCTCCGAAGCCGAGACTTCGGAGAT	CTGACAGCATCCTCTCATTCCTCTCGAACGGCGAATAC
CCCTCAATGAAGCTCCGAAGCCGAGACTTCGGAGAT	TGTTCGCTTTGATGCGTGTGATTGAGTTCGGCTT
CCCTCAATGAAGCTCCGAAGCCGAGACTTCGGAGAT	TTCGGCGCGTGTTCCTCCGCCGTTGCCGTTGTGGTGGGC
CCCTCAATGAAGCTCCGAAGCCGAGACTTCGGAGAT	GAGGTCATGGTGAAGTCGCGTTCGGTGCCGGTCTT
CCCTCAATGAAGCTCCGAAGCCGAGACTTCGGAGAT	CCGCCTCCCACTCCGCCACGCTGAGCGCCATATCGTC
CCCTCAATGAAGCTCCGAAGCCGAGACTTCGGAGAT

>NC_011835|3|1|642759-644162|PILER-CR
CCTCAATGAAGCTCCGAAGCCAAAACTTCGGAGATG	CCTCCTGATGGATCTCCACGACGTTGCTGGCCCTT
CCTCAATGAAGCTCCGAAGCCGAGACTTCGGAGATG	CCATCCCGACTGTGGCGGCGGCGTTCGGTGTCGCC
CCTCAATGAAGCTCCGAAGCCGAGACTTCGGAGATG	ACAGTGCGAACACAGTGCAGTCGGTGACGATCGCGC
CCTCAATGAAGCTCCGAAGCCGAGACTTCGGAGATT	CGGTCTTCTTGAGCTGGTCGGTGAGTGTCTTGAGCC
CCTCAATGAAGCTCCGAAGCCGAGACTTCGGAGATG	CAACGCCTTCGTTCGCCTCGTGGACTATCGCGGCCC
CCTCAATGAAGCTCCGAAGCCGAGACTTCGGAGATC	AGGTTCTCGAGGATGCTCACTATTTCCGTGAGGATGATC
CCTCAATGAAGCTCCGAAGCCGAGACTTCGGAGATC	TATACCCGTATGCAATGCTGTGCGCGTTGGATGCAAGC
CCTCAATGAAGCTCCGAAGCCGAGACTTCGGAGATT	GGCGCGAGCAGTATCACCACGTGGCTGCTCAACCGC
CCTCAATGAAGCTCCGAAGCCGAGACTTCGGAGATA	ACGGTTCGATGGTTCGCACAGTGAGTTGTTCACTCC
CCTCAATGAAGCTCCGAAGCCGAGACTTCGGAGATT	TCGTCTCCTCCCTGCGCCGCTGATTGACCTGTTTC
CCTCAATGAAGCTCCGAAGCCGAGACTTCGGAGATA	TTTCAGGCGGCATCAGACCTTGCGGCTGGGATTC
CCTCAATGAAGCTCCGAAGCCGAGACTTCGGAGATG	CGTGTGGTGGAAAAACCAGCCCGTCACCGAAGCGGCCC
CCTCAATGAAGCTCCGAAGCCGAGACTTCGGAGATT	CGCAGGTGAATATCGGTGGCGGCGGCTTGTCGTC
CCTCAATGAAGCTCCGAAGCCGAGACTTCGGAGATC	GGATAGTATCCTGCGTCGCGTCTCCAATGGCGAC
CCTCAATGAAGCTCCGAAGCCGAGACTTCGGAGATC	TGACAGCATCCTCTCATTCCTCTCGAACGGCGAATACC
CCTCAATGAAGCTCCGAAGCCGAGACTTCGGAGATT	GTTCGCTTTGATGCGTGTGATTGAGTTCGGCTTC
CCTCAATGAAGCTCCGAAGCCGAGACTTCGGAGATT	TCGGCGCGTGTTCCTCCGCCGTTGCCGTTGTGGTGGGCC
CCTCAATGAAGCTCCGAAGCCGAGACTTCGGAGATG	AGGTCATGGTGAAGTCGCGTTCGGTGCCGGTCTTC
CCTCAATGAAGCTCCGAAGCCGAGACTTCGGAGATC	CGCCTCCCACTCCGCCACGCTGAGCGCCATATCGTCC
CCTCAATGAAGCTCCGAAGCCGAGACTTCGGAGAT

Protein	Signature genes	Signature genes Name	Protein_function
NC_011835.1\|WP_004218204.1\|631005_631518_+\|DNA-mismatch-endonuclease-Vsr	unknown	unknown	gnl\|CDD\|226250
NC_011835.1\|WP_004269219.1\|644341_645613_-\|gamma-glutamylcysteine-synthetase	unknown	unknown	gnl\|CDD\|130503
NC_011835.1\|WP_004218233.1\|657786_658104_+\|exodeoxyribonuclease-VII-small-subunit	unknown	unknown	gnl\|CDD\|179195
NC_011835.1\|WP_004218235.1\|658104_659130_-\|endonuclease/exonuclease/phosphatase-family-protein	unknown	unknown	gnl\|CDD\|377028
NC_011835.1\|WP_004218212.1\|639182_640379_-\|type-I-U-CRISPR-associated-protein-Cas7	cas7	cd09738_cas7_CAS-I-U	gnl\|CDD\|378223
NC_011835.1\|WP_004218231.1\|653661_656088_-\|anaerobic-ribonucleoside-triphosphate-reductase	unknown	unknown	gnl\|CDD\|236436
NC_011835.1\|WP_012619748.1\|633063_633372_-\|helix-turn-helix-transcriptional-regulator	unknown	unknown	gnl\|CDD\|238045
NC_011835.1\|WP_004218228.1\|651220_651622_+\|DUF1304-domain-containing-protein	unknown	unknown	gnl\|CDD\|377753
NC_011835.1\|WP_004218229.1\|651884_652574_+\|hypothetical-protein	unknown	unknown	unknown
NC_011835.1\|WP_004218225.1\|645686_650363_-\|2-hydroxyacyl-CoA-dehydratase	unknown	unknown	gnl\|CDD\|226108
NC_011835.1\|WP_004218232.1\|656444_657743_+\|exodeoxyribonuclease-VII-large-subunit	unknown	unknown	gnl\|CDD\|272979
NC_011835.1\|WP_004269218.1\|633430_634477_-\|hypothetical-protein	csb3	cd09764_csb3_CAS-I-U	gnl\|CDD\|187733
NC_011835.1\|WP_004218205.1\|632521_632737_+\|antitoxin-VbhA-family-protein	unknown	unknown	gnl\|CDD\|375921
NC_011835.1\|WP_004218219.1\|641097_642729_-\|CRISPR-associated-endonuclease-Cas4/Cas1	cas1	cd09634_cas1_CAS-I:CAS-II:CAS-III:CAS-V	gnl\|CDD\|376633
NC_011835.1\|WP_004218209.1\|634480_637534_-\|hypothetical-protein	cas3	cd09696_cas3_CAS-I-U	gnl\|CDD\|274235
NC_011835.1\|WP_004218202.1\|629516_630068_-\|winged-helix-turn-helix-transcriptional-regulator	unknown	unknown	gnl\|CDD\|224759
NC_011835.1\|WP_004218203.1\|630325_630892_-\|NADPH-dependent-FMN-reductase	unknown	unknown	gnl\|CDD\|223508
NC_011835.1\|WP_014482306.1\|650606_651224_+\|DUF1211-domain-containing-protein	unknown	unknown	gnl\|CDD\|377696
NC_011835.1\|WP_072633051.1\|652570_653302_-\|anaerobic-ribonucleoside-triphosphate-reductase-activating-protein	unknown	unknown	gnl\|CDD\|379137
NC_011835.1\|WP_004218214.1\|640792_641086_-\|CRISPR-associated-endonuclease-Cas2	cas2	cd09725_cas2_CAS-I:CAS-II:CAS-III:CAS-V	gnl\|CDD\|187856

Protein	Function_ID	Function_description	E-value
NC_011835.1\|WP_004218204.1\|631005_631518_+\|DNA-mismatch-endonuclease-Vsr	gnl\|CDD\|226250	COG3727, Vsr, DNA G:T-mismatch repair endonuclease [DNA replication, recombination, and repair].	8.35049e-54
NC_011835.1\|WP_004269219.1\|644341_645613_-\|gamma-glutamylcysteine-synthetase	gnl\|CDD\|130503	TIGR01436, Glutamate--cysteine_ligase_chloroplastic, glutamate--cysteine ligase, plant type. This model represents one of two highly dissimilar forms of glutamate--cysteine ligase (gamma-glutamylcysteine synthetase), an enzyme of glutathione biosynthesis. The other type is modeled by TIGR01434. This type is found in plants (with a probable transit peptide), root nodule and other bacteria, but not E. coli and closely related species. [Biosynthesis of cofactors, prosthetic groups, and carriers, Glutathione and analogs].	6.6628e-50
NC_011835.1\|WP_004218233.1\|657786_658104_+\|exodeoxyribonuclease-VII-small-subunit	gnl\|CDD\|179195	PRK00977, PRK00977, exodeoxyribonuclease VII small subunit; Provisional.	1.25978e-10
NC_011835.1\|WP_004218235.1\|658104_659130_-\|endonuclease/exonuclease/phosphatase-family-protein	gnl\|CDD\|377028	pfam03372, Exo_endo_phos, Endonuclease/Exonuclease/phosphatase family. This large family of proteins includes magnesium dependent endonucleases and a large number of phosphatases involved in intracellular signalling. This family includes: AP endonuclease proteins EC:4.2.99.18, DNase I proteins EC:3.1.21.1, Synaptojanin an inositol-1,4,5-trisphosphate phosphatase EC:3.1.3.56, Sphingomyelinase EC:3.1.4.12, and Nocturnin.	2.71702e-23
NC_011835.1\|WP_004218212.1\|639182_640379_-\|type-I-U-CRISPR-associated-protein-Cas7	gnl\|CDD\|378223	pfam09617, Cas_GSU0053, CRISPR-associated protein GSU0053 (Cas_GSU0053). This entry is found in CRISPR-associated (cas) proteins in the genomes of Geobacter sulfurreducens PCA and Desulfotalea psychrophila LSv54 (both Desulfobacterales from the Deltaproteobacteria), Gemmata obscuriglobus (a Planctomycete), and Actinomyces naeslundii MG1 (Actinobacteria).	4.74467e-24
NC_011835.1\|WP_004218231.1\|653661_656088_-\|anaerobic-ribonucleoside-triphosphate-reductase	gnl\|CDD\|236436	PRK09263, PRK09263, anaerobic ribonucleoside triphosphate reductase; Provisional.	0
NC_011835.1\|WP_012619748.1\|633063_633372_-\|helix-turn-helix-transcriptional-regulator	gnl\|CDD\|238045	cd00093, HTH_XRE, Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators.	0.00139643
NC_011835.1\|WP_004218228.1\|651220_651622_+\|DUF1304-domain-containing-protein	gnl\|CDD\|377753	pfam06993, DUF1304, Protein of unknown function (DUF1304). This family consists of several hypothetical bacterial proteins of around 120 residues in length. The function of this family is unknown.	8.78634e-28
NC_011835.1\|WP_004218225.1\|645686_650363_-\|2-hydroxyacyl-CoA-dehydratase	gnl\|CDD\|226108	COG3580, COG3580, Uncharacterized protein conserved in bacteria [Function unknown].	9.43104e-132
NC_011835.1\|WP_004218232.1\|656444_657743_+\|exodeoxyribonuclease-VII-large-subunit	gnl\|CDD\|272979	TIGR00237, exodeoxyribonuclease_VII_large_subunit, exodeoxyribonuclease VII, large subunit. This family consist of exodeoxyribonuclease VII, large subunit XseA which catalyses exonucleolytic cleavage in either the 5'->3' or 3'->5' direction to yield 5'-phosphomononucleotides. Exonuclease VII consists of one large subunit and four small subunits. [DNA metabolism, Degradation of DNA].	7.32407e-149
NC_011835.1\|WP_004269218.1\|633430_634477_-\|hypothetical-protein	gnl\|CDD\|187733	cd09764, Csb3_I-U, CRISPR/Cas system-associated RAMP superfamily protein Csb3. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; RAMP superfamily protein; Might be a catalytically active RNA endoribonuclease.	2.25485e-177
NC_011835.1\|WP_004218205.1\|632521_632737_+\|antitoxin-VbhA-family-protein	gnl\|CDD\|375921	pfam18495, VbhA, Antitoxin VbhA. VbhT is a bacterial Fic protein of the mammalian pathogen B. schoenbuchensis7,8. It is composed of an N-terminal FIC domain and a C-terminal BID domain. FIC domains are known to catalyse adenylylation (also called AMPylation). This entry represents VbhA, an antitoxin that binds FIC domain (filamentation induced by cyclic AMP) of VbhT and inhibits its activity. It inhibits the adenylylation activity of VbhT by positioning close to the putative ATP-binding site, hence competing with ATP binding.	7.38963e-06
NC_011835.1\|WP_004218219.1\|641097_642729_-\|CRISPR-associated-endonuclease-Cas4/Cas1	gnl\|CDD\|376633	pfam01867, Cas_Cas1, CRISPR associated protein Cas1. Clustered regularly interspaced short palindromic repeats (CRISPRs) are a family of DNA direct repeats found in many prokaryotic genomes. This family of proteins corresponds to Cas1, a CRISPR-associated protein. Cas1 may be involved in linking DNA segments to CRISPR.	1.0918e-95
NC_011835.1\|WP_004218209.1\|634480_637534_-\|hypothetical-protein	gnl\|CDD\|274235	TIGR02621, CRISPR-associated_helicase_Cas3, CRISPR-associated helicase Cas3, subtype Dpsyc. This model describes a CRISPR-associated putative DEAH-box helicase, or Cas3, of a subtype found in Actinomyces naeslundii MG1, Geobacter sulfurreducens PCA, Gemmata obscuriglobus UQM 2246, and Desulfotalea psychrophila. This protein includes both DEAH and HD motifs.	1.40435e-50
NC_011835.1\|WP_004218202.1\|629516_630068_-\|winged-helix-turn-helix-transcriptional-regulator	gnl\|CDD\|224759	COG1846, MarR, Transcriptional regulators [Transcription].	1.71117e-10
NC_011835.1\|WP_004218203.1\|630325_630892_-\|NADPH-dependent-FMN-reductase	gnl\|CDD\|223508	COG0431, COG0431, Predicted flavoprotein [General function prediction only].	1.20079e-13
NC_011835.1\|WP_014482306.1\|650606_651224_+\|DUF1211-domain-containing-protein	gnl\|CDD\|377696	pfam06736, DUF1211, Protein of unknown function (DUF1211). This family represents a conserved region within a number of hypothetical proteins of unknown function found in eukaryotes, bacteria and archaea. These may possibly be integral membrane proteins.	2.98049e-27
NC_011835.1\|WP_072633051.1\|652570_653302_-\|anaerobic-ribonucleoside-triphosphate-reductase-activating-protein	gnl\|CDD\|379137	pfam13353, Fer4_12, 4Fe-4S single cluster domain. This family includes proteins containing domains which bind to iron-sulfur clusters. Members include bacterial ferredoxins, various dehydrogenases, and various reductases. The structure of the domain is an alpha-antiparallel beta sandwich.	1.52583e-70
NC_011835.1\|WP_004218214.1\|640792_641086_-\|CRISPR-associated-endonuclease-Cas2	gnl\|CDD\|187856	cd09725, Cas2_I_II_III, CRISPR/Cas system-associated protein Cas2. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas2 is present in majority of CRISPR/Cas systems along with Cas1; RNAse specific to U-rich regions; Possesses an RRM/ferredoxin fold.	8.4419e-18

>NC_011835.1|WP_004218219.1|641097_642729_-|CRISPR-associated-endonuclease-Cas4/Cas1
MKYAENNAMKRGEGLEDTLPISLICDFIFCPRRAWLEIQGEKIESLQMERGFHDHRAVDDANGGRGDTDYRAVNVNHQGWGLSGRLDAVRLNEDNGVIIREYKATPVRRSMDVTHAMRIQLALQAACMEDMGYRVDGTEIFFTSHHRIVPVELRKSDYEEAYGSVQEVRKLIECETAPLPFEDDPRCMRCSHAGICLPEERAHNIPEHRIMVKVPDHAVTHLATPGARAYLKSGRMHVSKNGDEITSVPLDSIQALQIHGNVDVSSGLMRELMWRNIPILWCSGTGRLMGWSVSSYGPNGETRVAQHVASHEGRLDLAREFISAKIHNQIVLLRRSDKNNNVLFDMKHIEKSVVNANRIQDILSLEGQAAALYFSQFHHLISVNKRNEWPWLERMRHPAPDPLNALLDYTYSLLLSDCIRAIVSCGLDAHAGFLHSSKRNKPALALDLMEEFRAPIADSVVQTVVNNGEIKRNGFANVMGSVRLRDETRKTLIGAYERRMATELKHPVYAYRASWRRIVEIQARMVLGRLEGSLERYRGIRVR
>NC_011835.1|WP_004218214.1|640792_641086_-|CRISPR-associated-endonuclease-Cas2
MNNLMQRYIIAYDIKDDSRRIRVSKLLQSYGNRLQYSVFLMEMREVRLVRMEERLHTLINGAEDSVVIARLDDAKTSESIVFIGSRNYEDVRVPTVI
>NC_011835.1|WP_004218212.1|639182_640379_-|type-I-U-CRISPR-associated-protein-Cas7
MMRKLTVQDLNEAAKIGGSNALTEVTSLAPAAGMGSIVAPAKYTAGNGSTYVYEKRWVNDECVDTVLIDSRTSQANRLEDYISRAIEVGHPIFSKMPQVRVRYEMIPGDESSVRYFDDVQLPHRAVDAHIRIAEFSESDKVKYMAARNSSLEDLSAMLAISPVTVMFGCWDSTRNKNQLRIPASFNGEIYAVLADQTHESPIHRAGARIDPVAAGVHLTKNEAKKIAERIKGTMNDKKLSKFASSGDGSTIVIGAIPPSTDANALDGIAVRSITRTHVLSFSMLRAMRFGKGPEGDEAIRVLLAAALINAMVGSNAELHLRENCFLVEADEPKTVLDRRGGKHDDLEMLTLEDADELLAQAYAQAQKKAGIDWHGQIITVQGDPAVIESASAADDDDR
>NC_011835.1|WP_004218209.1|634480_637534_-|hypothetical-protein
MEMNATTPNEMLVELYDLFVESLHQGRKPYLWQTRLMREVVNNGQWMKLISAPTGSGKTAVIDVHLFVNALAGLAALDDIPLPKELNHLLKSLSLDAVPRRMAVTVNRRGIVDDQYLEASAACARINDVASLDDDTESEILKLIAVGLYARQYSELMDRQWTFDQLAFQCQEQGKVVCSAQRLRGGLDDKADMRVWRYKPLECQILCGTPDMIGSRLLFSGYGVSDAAKPIEAALLAYDAVIVVDEAQLSRQFAYTAQQIPRIEACIRQGEPLPVSPLQVVVTTATPSGENISNLQDEQSICGVEEADFKIDLELRRRLRTPRPIQVLSVDDKQIATCMAKESIALQERLGGVVVCFVNTVPRASEVVRRLREALGKDAGDNAVRAFVGPMRDYERDQFVQRLDSTEPLYDAIRGDQSAITQTGLKFVVATQTLEAGIDADFSGMISELAPAASLVQRAGRVNRRGLRPEGPVVICCQNSGKIRGPYMKEDLTAAQMWLESLPVEGLTAWSSVLQPPAPAQLERMVLQRLEWWDVENLSHTSEDVFAEHRAAGRPYPADVDLWLRDDLADRVTPDVAVVIRTLPQDDYLAQRLLATTPPDSRELFPVTSYAMLDALQNKLKGRRAFIMRTNSSENGNAVHLLDGQADSDPTLRSGDVLIVDDGARVFSEGIPMLDPFSKDDKHSKKLQDEITSPGDVFNKCQQSMAVLHANREKQPALYEELSEVLRAETDTDETVEAEYQGIDVSKYPNLQEALNSCAINNHGFRIAFVDGFIDGDSSDSSVFIVLQSSDAADGDQLQEIGRFNRQGPVLLDGPGSHQESVGSRAELFAAKLGFDSRLVADIRTAGLHHDDGKKDPRFQTLLRYRMPNVPAEPLAKSMYRSSSWERAKRIELRLDGWRHEQRSAAECWALDSESLQAHDKELVTRLAGTSHGHGRSMFPMNAQQVIPDAIIQTVSEENGDGSQTIHAIRSAAEELFDAGYWQSIMERTNERYGLWGIAFLETLLRAADVTISMEGR
>NC_011835.1|WP_004269218.1|633430_634477_-|hypothetical-protein
MSVLRIPADYDDAFSHMLGFGLASILEDAVEDRICRLWWSGRHTLMVETNDEITEMECAHIVRAHAERWHKSQWLNARGSYAGKGKTVATLSPRIGTVAGREEWVALERDRRDAIDSLRTTLDERYIGALGEPSYWSLNRTKATPEIQQKFGASLWEMTPRNRGNEFVTMRLLKLASIITARTAEKVHSGLFGLTNVDELAGTEDSHTPTGLKVPSRTDNARAWCALFGFSNCPVYRSVHYETSPTAGFIRHDSGGGPSWHVVLPLTEKSWTLAKYRSVIRSYALDYVGENALHLDQDSLSDSTVALYAELCRWLRDQGLRYCMLFQRHGTQAKSPEYWLLRGQLIRL
>NC_011835.1|WP_012619748.1|633063_633372_-|helix-turn-helix-transcriptional-regulator
MHTTLDLSQYNDVTAYADAVHRPVVHVDYLPTPQAVARRVREAVDDRHLSMEQLAKDAHVSIQAAYSLRDSGLASLSEARRVFAVLDIHVHAYPVEMVPLSL
>NC_011835.1|WP_004218205.1|632521_632737_+|antitoxin-VbhA-family-protein
MSVKESDVEMVRAAKAARNTRNLALALHSAEMEGGHVSDVLLHEAHDYANGLIDAATLGLRVCARYGLNDR
>NC_011835.1|WP_004218204.1|631005_631518_+|DNA-mismatch-endonuclease-Vsr
MNKARKGAQWYARTIHCPGDTGGVAQSPSHPESPYARGTRSYTMSRIRGKDTSIEKTVRSYLFARGFRFRKNDKRYPGHPDIVLPKYRTIVFVNGCFWHMHEGCESFHMPKSNVEFWAAKLTRNRDRDRRQHEQLRQMGWRVIDVWECELRGDAREARLERLVGQIAEGV
>NC_011835.1|WP_004218203.1|630325_630892_-|NADPH-dependent-FMN-reductase
MADKPTIAFVETSLTDGSFEADLAKEIMGIVGDRAEAITIDYEDLPLAGEDPEYPLPEAALAVRDKLGNADAVWVVVSEYKKEIPDSLRNLFDWLSLPSTKDEEGKNVLDQKPVAISGVGGFEELHPRIMVGDLLEDAGMRLFPVEVGLSVPDEAVETGDWAMTGADQEALRTQADDFLTFVSENEVK
>NC_011835.1|WP_004218202.1|629516_630068_-|winged-helix-turn-helix-transcriptional-regulator
MDRVQGVNSPGMLRPSLEIKALHNLIGRYWNGIVPPDSMMSGANMPIVQYLHEHRDSDVFQYDIERAFSITRSTASRVLGLMEKKGLITRSAVDWDARVRKIELTPTASDLVVEIMRAAHQLETTLFTGFTPDEQERFMDDLARMRANLVETGLVGSERTAVEPATRTRQDATHQQQKGDEAA
>NC_011835.1|WP_004269219.1|644341_645613_-|gamma-glutamylcysteine-synthetase
MTAPRVSYAHLLVQPNPRHVRSLVRFFEEGCSAPGTGGFGVEIEHLPVHNADDTAVTYGEPNGVEELLRRLRPYYDSAQEYWQDDHLVGLAREGIAISLEPGGQIETSIGILRKPKDLLELHGQFMREATPILDELDFRLVNYGYQPKSSYADIPLNPKLRYAAMNEYLGRIGQFGPCMMRASASTQVSIDYTSERDAIDKMRLGTAIGPILAWFFRNTPYFEGAPNPWPLCRQRMWDYLDVQRTNVTPGLYDERFSWEDYAADVLSTPLMFADLTHTPEAEGASVHGTEFTAFYTTAADLYPDRELNAYEINHVLSTHFNDVRLKNFIEMRHWDSLPIERAELLTQIVSNLFYDVERRTSLESYFSGLTGEDVHAAKAVLQARGGDAKPYDQPMDYWAEVLGVGDALADVPGDAKWPEVRQG
>NC_011835.1|WP_004218225.1|645686_650363_-|2-hydroxyacyl-CoA-dehydratase
MASLVQEPSSISQTLNTEPRPLRIGLDIGSTTVKAVVLDDSDSLDATLFADYRRHHANVRATMEGLLRDIRAHLAELGRADEPVRLAITGSGGLALADAVHVPFVQEVIAETRAIDEAIPQADVIIELGGEDAKITYLKPTPEQRMNGSCAGGTGAFIDQMSTLLDTDAAGLNEMAKYYQTLYPIASRCGVFAKTDLQPLINDGAAKPDLAASIFTAVATQTIAGLASGRPIHGTVVFLGGPLFFMSELREAFRRALDGKVDEFITPTDAHLYVAYGAALAVGEPGQIEHADEYPARSLDDIINALEDLKNLPSNTATMPPLFDTAADRDAFNARHHREHVHVGTLEGARGPHFLGIDAGSTTIKATLVNDDREIVWSSYATNDGSPLTAAIEIVKRIQSELPSDAWIARSCATGYGEGLITTGLHLDEGVVETMAHYRGAEMVSPGVTAVIDIGGQDMKYLAVTDGVIDSIAVNEACSSGCGSFLQTFARSMGLTIEEFTQAALASEHPVDLGSRCTVFMNSSVKQAQKEGASIEDIAAGLCYSVVRNALYKVIKLRDSGELGSTVVVQGGTFLNDAVLRAFELLTEREVTRPNIAGLMGAYGAALTARMHYDDIADDTDGDTDAAGVHVACIDGVDHTVSSILHGTALDELSMTTERDVCKLCQNHCKLTITTFHDGSRYVTGNRCERGGDAKRKRSDRPNLYDFKYKRAFAYRRLTDKKATRGEIGIPRVLNMYENYPFWFTLLTSLGFKVVISGRSNHELFETGIESIASENICYPAKLVHGHIKWLLNKGIRTIFYPCVSFEDDLVPESDNHYNCPVVANYPVVIEANMPELRADGIRFMRPYFNLSKHSLMVDRIVEEFAWAGVTREEAEAAVAAAYAEDTVFKHDVQQEGVRALAYMKEHNCRGIVLAGRPYHVDPEVNHGIPETICSLGMVVLSEDSVSWLDPNDVPALTAYLAEDETDPAAHTSEGFRHVNDRKLTTMPLRVMNQWAYHARLYRAAQFVASWPGLELVQLNSFGCGLDAVTTDQVSEILADKADVYTMLKIDEVSNLGAAKIRLRSLKAAVEERERNAQRAATPAASAGTFRHTGTAAPTPGRQILLDAVMGRQAGGAQQNRQSATMSAYANRVPFGKDMRRDYTIVAPQMSPIHFRLVEAAIRASGYKFDVLEHASKTDVETGLKYVNNDACYPAIMTVGQLVEAIKSRRYDPDSTALAISQTGGMCRATNYFALIRKALVDAGYPQIPVIAISTQGFVDNPGFTPTVPLLHRAAKSLIIGDLLMKCLYRVRPYEANPGSANRLYERWNVIVRETLLNHGMSKTAKMLYGRAYWPYAKLVAKIVESFDALPLRDVERKVRVGVVGEILVKYQPDANNHVVEVIESQDCEAVVPGIIDFMTMRPYINDWNEHNLGTGRNKALYTAFKGVIHTYMKPVNDALESSGGKFEKDLPMDQLVAKAQTVTSIGVQAGEGWLLTGEIVELIESGCPNIICAQPFACLPNHVTGRGMFGKIRRLYPQANIVSIDYDPGASEANQLNRIKLMIAAAKKNAAAGRSSV
>NC_011835.1|WP_014482306.1|650606_651224_+|DUF1211-domain-containing-protein
MIGSRRVWECAMSKERVVAFTDAVLAIIMTILVLDLDKPDPLTWSGFGKLWPQFLAYAFSFFWLGSMWVHLHIEWSGVKLVDQPVLWTSITLLFFCSLIPYSTSLVAGNVLSWDLAIKIVGIMITLTIWPPAMLVFTLAAAMFLFLKSASAERRMQVKIKKDALANNGMATPDDVAAVGGSAEEYLAAIEAAKQAAKEADEGDKQ
>NC_011835.1|WP_004218228.1|651220_651622_+|DUF1304-domain-containing-protein
MNTALITASIFAMLAGLLHVYIFVMESFLWTSRSTRETFSMGADEAEQTKEMAFNQGFYNLFLAIMSIGGAIVLWCGVTVVGVTLMTAGSASMFCAALVLLCTAPDKHSAAIKQIFFPALTLIALLVALILFA
>NC_011835.1|WP_004218229.1|651884_652574_+|hypothetical-protein
MAIITVVAIVGGVVGGIIYKNKHDEAYARCQTAVSEFSEARKALLDTTSDSPALQKLVRNALGVDKILDAAADAASAAEGTVAQQGCAANATIIQLNLVANTLNSATESLRKSTAQIVRGASADTDNTGDESESAASSDTEDVAQAKRNLQEAIDQGRALLDTLKQRYADSAVGRQLTAGFEAALDLAQEKFDESGIKDSRYYKAAQATLDEATNAVNAWIDRQAQKAD
>NC_011835.1|WP_072633051.1|652570_653302_-|anaerobic-ribonucleoside-triphosphate-reductase-activating-protein
MNDSANGTWRSTGKPRLHDFAAGETGRGPAIPTPMSNNPKPGQWTNRMSHNMIADYKRFLMTDGEGIRCSLYVSGCPFHCVECYNSSIWDFQAGHEYNDKLEAQIMDDLAQSFVQGITFLGGEPLLNTGVLLPLARKIRERFGHTKDIWCWTGYTWEELMRDGETQDKLDLLHEIDILVDGRYIKTLHDSLLQFRGSRNQRILDVQESFRQGKPVVWAKLHDQERFIPEIYGKERAAGEGDAS
>NC_011835.1|WP_004218231.1|653661_656088_-|anaerobic-ribonucleoside-triphosphate-reductase
METQILGDTLSRTVVGDGDDVFEGMFTDRVLVEKRDGRVVDFDPVNIVVAVKSAFADLDKEVGPQEERMILDIANQIEGEIRERYNGPAKIEDIQNLVEHALIEDHLYEVARTYTNYRLNKDIQRAKATDINEAVSRLVNRDESLVRENANKDSNVYATQRDLLAGAVSKASAFSMLPDAVANAHMKGDIHFHDADYSPFTSMNNCSLPDFGDMLKHGFALGNAMMDSPKSIGTASTQITQIIKDIAGAQYGGQTVNRADEMLEEYAKRDYVKNLDMAHAMIPDSTPIEVARDMVAGLKAQEPRWLHFENREPLPADEAFDTNAPELEQIREIYAKIMTRKAIYDAMQTMEYQINSNRVSNGQTPFVTVGFGLGMSWFAREIQRAILLNRIRGLGKERHTAIFPKLVFTVKHGVNADEGDPNYDLKQLALECATKRMYPDVVFYDNIVKITGSFKAPMGCRSFLQGWIDPKTGKDVEDGRMNLGVVTVNVPRIALESHGDVERFWKIFDERMEVAHQALQFRIMRCKQATPVNAPTLFRYGAFGRLETNENVDQLFRNERATVSLGYIGLYEATAVFFGKDWMRDHAWDPEGKDFALSIVRRMNELCKQWSKAEGYHYSVYSTPAESLTDRFNRMDRKKFGKVEGVTDHDFYTNSFHYPVWLQPTPMEKLDYEKDFPYYASGGFINYCEFPCLQANPKALEAVWDYAYNIGIGYLGTNTPIDHCFVCGFEGDFAPTEEGFKCPECGNSDPDKCNVTKRTCGYLGNPVQRPMVHGRHEEIAHRVKHMAGETGHVTLADGETREWFEETK
>NC_011835.1|WP_004218232.1|656444_657743_+|exodeoxyribonuclease-VII-large-subunit
MVFNNGYQTGYRQGYAPAPAAGPNELPRMAAQTTAENPWPVSMVSQKFHSAVERWPAVWMEGQIIEINTRRSGSAYLTLRDNDQDVSMSVLGFGAFAQMARDYKQGDRVVVHGKADLYVKSTRLSLRADMIKRVGAGNLQEQINQLRMRLKGEGLFDESRKVALPEFPKNIGLICAPQARAEGDVVMNVNLRWPGVRFTIVHAHVQGEQCPPDIVSAIQQLDADPNVDVIIVARGGGSFEDLMGFSDERVVRATAACATPIISAIGHEDDWTLIDLAADVRASTPTDAAKRVVPDVREQQQLITEGINRMRTFIANRAGNEERLVEGYANRPSLTQPLTMLIPHERDIADAVSAMRNGLRRIVDEEQMQVERLAATLRALSPQSTLDRGYAVLQNADGAIIDDASQVQVGDELTLTLRRGKVVSQAQAVYDE
>NC_011835.1|WP_004218233.1|657786_658104_+|exodeoxyribonuclease-VII-small-subunit
MAEDMEITEVSETEPQTASSLSQEERERIAQLPYEQARDELIQAVRALENGGLSLEDSMKQWELGEALAQRAQSLLSTIRAKLDAAQQAQAQTANTAGTQSNLES
>NC_011835.1|WP_004218235.1|658104_659130_-|endonuclease/exonuclease/phosphatase-family-protein
MAMMRKHRVLGAIAGLLALASLCSCALRLLPVDLQTLPYVSVVLAATPWFAIVSVVSLVLALISTRWVTAIVAGVCLAIQVCWQLPFYHNGTPLSGSALSSQSLPRADTADAVARLMTCNVYKGHADAAAIVNAVRDNHVEVLALQETTPDFLKRLEEAGISQLLPYSQTSSADGYFGNALFSALPFENPSQTDVDSIASYMPGGTVGFDNGAIPVRFVSVHTQSPTEGRFEKWSRSIAELKQLNEHPDTDYILMGDFNSTWDHAVFRDMLGTRFQDAAEVSGHGLVFTWPADRKYLPAFAGIDHIVTSKDVTIGQVNSLTIPGSDHRALLATVDVSGLRH

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Crispr_ID: NC_011835_4

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_011835_4

906923-907000

Orphan

Consensus_repeat	Method
CACGGAATCTTCCGTGTGATCGACCG	CRISPRCasFinder

1 spacers

The CRISPR arrays of NC_011835_4

>merge|NC_011835|4|906923-907000|CRISPRCasFinder
CACGGAATCTTCCGTGTGATCGACCGCAGACGCCGTGGAAAACGGCGCATTGCACGGAAGCTTCCGTGTGATCGACCG

>NC_011835|4|4|906923-907000|CRISPRCasFinder
CACGGAATCTTCCGTGTGATCGACCG	CAGACGCCGTGGAAAACGGCGCATTG
CACGGAAGCTTCCGTGTGATCGACCG

Protein	Signature genes	Signature genes Name	Protein_function
NC_011835.1\|WP_193338208.1\|913249_914545_-\|ISL3-like-element-IS2001-family-transposase	unknown	unknown	gnl\|CDD\|376574
NC_011835.1\|WP_004219086.1\|892661_894140_-\|MFS-transporter	unknown	unknown	gnl\|CDD\|340879
NC_011835.1\|WP_012619808.1\|895358_896405_-\|LacI-family-DNA-binding-transcriptional-regulator	unknown	unknown	gnl\|CDD\|224525
NC_011835.1\|WP_004219443.1\|897314_897584_+\|type-II-toxin-antitoxin-system-RelB/DinJ-family-antitoxin	unknown	unknown	gnl\|CDD\|274102
NC_011835.1\|WP_004269164.1\|911658_912990_+\|ABC-transporter-substrate-binding-protein	unknown	unknown	gnl\|CDD\|379175
NC_011835.1\|WP_004218732.1\|916864_917116_+\|hypothetical-protein	unknown	unknown	unknown
NC_011835.1\|WP_004218733.1\|916050_916692_-\|sugar-O-acetyltransferase	unknown	unknown	gnl\|CDD\|100047
NC_011835.1\|WP_004219382.1\|909524_911300_-\|glycoside-hydrolase-family-13-protein	unknown	unknown	gnl\|CDD\|200471
NC_011835.1\|WP_004219365.1\|908593_909262_+\|histidine-phosphatase-family-protein	unknown	unknown	gnl\|CDD\|366010
NC_011835.1\|WP_004219369.1\|907138_907915_-\|nitroreductase-family-protein	unknown	unknown	gnl\|CDD\|380322
NC_011835.1\|WP_004219085.1\|894222_895176_-\|nucleoside-hydrolase	unknown	unknown	gnl\|CDD\|239116
NC_011835.1\|WP_004219373.1\|905925_906516_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|341046
NC_011835.1\|WP_004218731.1\|917199_919899_-\|aconitate-hydratase-AcnA	unknown	unknown	gnl\|CDD\|236445
NC_011835.1\|WP_004218730.1\|919966_922537_-\|HAD-IC-family-P-type-ATPase	unknown	unknown	gnl\|CDD\|319795
NC_011835.1\|WP_004219371.1\|906561_906813_+\|hypothetical-protein	unknown	unknown	unknown
NC_011835.1\|WP_004219367.1\|908014_908431_-\|DUF4235-domain-containing-protein	unknown	unknown	gnl\|CDD\|379422
NC_011835.1\|WP_004219444.1\|897748_899083_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|235057
NC_011835.1\|WP_004269239.1\|890439_891453_+\|ribose-phosphate-diphosphokinase	unknown	unknown	gnl\|CDD\|179535
NC_011835.1\|WP_004219087.1\|891590_892559_-\|ribokinase	unknown	unknown	gnl\|CDD\|238579
NC_011835.1\|WP_004219452.1\|899117_899654_-\|NAD+-synthetase	unknown	unknown	gnl\|CDD\|235057

Protein	Function_ID	Function_description	E-value
NC_011835.1\|WP_193338208.1\|913249_914545_-\|ISL3-like-element-IS2001-family-transposase	gnl\|CDD\|376574	pfam01610, DDE_Tnp_ISL3, Transposase. Transposase proteins are necessary for efficient DNA transposition. Contains transposases for IS204, IS1001, IS1096 and IS1165.	1.2097e-57
NC_011835.1\|WP_004219086.1\|892661_894140_-\|MFS-transporter	gnl\|CDD\|340879	cd17321, MFS_MMR_MDR_like, Methylenomycin A resistance protein (also called MMR peptide) and similar multidrug resistance (MDR) transporters of the Major Facilitator Superfamily. This family is composed of bacterial, fungal, and archaeal multidrug resistance (MDR) transporters including several proteins from Bacilli such as methylenomycin A resistance protein (also called MMR peptide), tetracycline resistance protein (TetB), and lincomycin resistance protein LmrB, as well as fungal proteins such as vacuolar basic amino acid transporters, which are involved in the transport into vacuoles of the basic amino acids histidine, lysine, and arginine in Saccharomyces cerevisiae, and aminotriazole/azole resistance proteins. MDR transporters are drug/H+ antiporters (DHA) that mediate the efflux of a variety of drugs and toxic compounds, and confer resistance to these compounds. For example, MMR confers resistance to the epoxide antibiotic methylenomycin while TetB resistance to tetracycline by an active tetracycline efflux. MMR-like MDR transporters belong to the Major Facilitator Superfamily (MFS) of membrane transport proteins, which are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	1.23068e-16
NC_011835.1\|WP_012619808.1\|895358_896405_-\|LacI-family-DNA-binding-transcriptional-regulator	gnl\|CDD\|224525	COG1609, PurR, Transcriptional regulators [Transcription].	1.13138e-93
NC_011835.1\|WP_004219443.1\|897314_897584_+\|type-II-toxin-antitoxin-system-RelB/DinJ-family-antitoxin	gnl\|CDD\|274102	TIGR02384, Putative_antitoxin_RelB, addiction module antitoxin, RelB/DinJ family. Plasmids may be maintained stably in bacterial populations through the action of addiction modules, in which a toxin and antidote are encoded in a cassette on the plasmid. In any daughter cell that lacks the plasmid, the toxin persists and is lethal after the antidote protein is depleted. Toxin/antitoxin pairs are also found on main chromosomes, and likely represent selfish DNA. Sequences in the seed for this alignment all were found adjacent to toxin genes. The resulting model appears to describe a narrower set of proteins than pfam04221, although many in the scope of this model are not obviously paired with toxin proteins. Several toxin/antitoxin pairs may occur in a single species. [Cellular processes, Toxin production and resistance, Mobile and extrachromosomal element functions, Other].	5.21989e-14
NC_011835.1\|WP_004218733.1\|916050_916692_-\|sugar-O-acetyltransferase	gnl\|CDD\|100047	cd03357, LbH_MAT_GAT, Maltose O-acetyltransferase (MAT) and Galactoside O-acetyltransferase (GAT): MAT and GAT catalyze the CoA-dependent acetylation of the 6-hydroxyl group of their respective sugar substrates. MAT acetylates maltose and glucose exclusively at the C6 position of the nonreducing end glucosyl moiety. GAT specifically acetylates galactopyranosides. Furthermore, MAT shows higher affinity toward artificial substrates containing an alkyl or hydrophobic chain as well as a glucosyl unit. Active MAT and GAT are homotrimers, with each subunit consisting of an N-terminal alpha-helical region and a C-terminal left-handed parallel alpha-helix (LbH) subdomain with 6 turns, each containing three imperfect tandem repeats of a hexapeptide repeat motif (X-[STAV]-X-[LIV]-[GAED]-X).	2.64242e-97
NC_011835.1\|WP_004219382.1\|909524_911300_-\|glycoside-hydrolase-family-13-protein	gnl\|CDD\|200471	cd11332, AmyAc_OligoGlu_TS, Alpha amylase catalytic domain found in oligo-1,6-glucosidase (also called isomaltase; sucrase-isomaltase; alpha-limit dextrinase), trehalose synthase (also called maltose alpha-D-glucosyltransferase), and related proteins. Oligo-1,6-glucosidase (EC 3.2.1.10) hydrolyzes the alpha-1,6-glucosidic linkage of isomaltooligosaccharides, pannose, and dextran. Unlike alpha-1,4-glucosidases (EC 3.2.1.20), it fails to hydrolyze the alpha-1,4-glucosidic bonds of maltosaccharides. Trehalose synthase (EC 5.4.99.16) catalyzes the isomerization of maltose to produce trehalulose. The Alpha-amylase family comprises the largest family of glycoside hydrolases (GH), with the majority of enzymes acting on starch, glycogen, and related oligo- and polysaccharides. These proteins catalyze the transformation of alpha-1,4 and alpha-1,6 glucosidic linkages with retention of the anomeric center. The protein is described as having 3 domains: A, B, C. A is a (beta/alpha) 8-barrel; B is a loop between the beta 3 strand and alpha 3 helix of A; C is the C-terminal extension characterized by a Greek key. The majority of the enzymes have an active site cleft found between domains A and B where a triad of catalytic residues (Asp, Glu and Asp) performs catalysis. Other members of this family have lost the catalytic activity as in the case of the human 4F2hc, or only have 2 residues that serve as the catalytic nucleophile and the acid/base, such as Thermus A4 beta-galactosidase with 2 Glu residues (GH42) and human alpha-galactosidase with 2 Asp residues (GH31). The family members are quite extensive and include: alpha amylase, maltosyltransferase, cyclodextrin glycotransferase, maltogenic amylase, neopullulanase, isoamylase, 1,4-alpha-D-glucan maltotetrahydrolase, 4-alpha-glucotransferase, oligo-1,6-glucosidase, amylosucrase, sucrose phosphorylase, and amylomaltase.	0
NC_011835.1\|WP_004219365.1\|908593_909262_+\|histidine-phosphatase-family-protein	gnl\|CDD\|366010	pfam00300, His_Phos_1, Histidine phosphatase superfamily (branch 1). The histidine phosphatase superfamily is so named because catalysis centers on a conserved His residue that is transiently phosphorylated during the catalytic cycle. Other conserved residues contribute to a 'phosphate pocket' and interact with the phospho group of substrate before, during and after its transfer to the His residue. Structure and sequence analyses show that different families contribute different additional residues to the 'phosphate pocket' and, more surprisingly, differ in the position, in sequence and in three dimensions, of a catalytically essential acidic residue. The superfamily may be divided into two main branches. The larger branch 1 contains a wide variety of catalytic functions, the best known being fructose 2,6-bisphosphatase (found in a bifunctional protein with 2-phosphofructokinase) and cofactor-dependent phosphoglycerate mutase. The latter is an unusual example of a mutase activity in the superfamily: the vast majority of members appear to be phosphatases. The bacterial regulatory protein phosphatase SixA is also in branch 1 and has a minimal, and possible ancestral-like structure, lacking the large domain insertions that contribute to binding of small molecules in branch 1 members.	5.61919e-50
NC_011835.1\|WP_004219369.1\|907138_907915_-\|nitroreductase-family-protein	gnl\|CDD\|380322	cd02146, NfsA-like, nitroreductase similar to Escherichia coli NfsA. This family contains NADPH-dependent flavin reductase and oxygen-insensitive nitroreductase. These enzymes are homodimeric flavoproteins that contain one FMN per monomer as a cofactor. Flavin reductase catalyzes the reduction of flavin by using NADPH as an electron donor. Oxygen-insensitive nitroreductase, such as NfsA protein in Escherichia coli, catalyzes reduction of nitrocompounds using NADPH as electron donor.	6.08897e-66
NC_011835.1\|WP_004219085.1\|894222_895176_-\|nucleoside-hydrolase	gnl\|CDD\|239116	cd02650, nuc_hydro_CaPnhB, NH_hydro_CaPnhB: A subgroup of nucleoside hydrolases similar to Corynebacterium ammoniagenes Purine/pyrimidine nucleoside hydrolase (pnhB). Nucleoside hydrolases cleave the N-glycosidic bond in nucleosides generating ribose and the respective base. These enzymes vary in their substrate specificity. .	2.91843e-133
NC_011835.1\|WP_004219373.1\|905925_906516_+\|hypothetical-protein	gnl\|CDD\|341046	cd17503, MFS_LmrB_MDR_like, Bacillus subtilis lincomycin resistance protein (LmrB) and similar multidrug resistance (MDR) transporters of the Major Facilitator Superfamily. This subfamily is composed of multidrug resistance (MDR) transporters including Bacillus subtilis lincomycin resistance protein LmrB, and several proteins from Escherichia coli such as the putative MDR transporters EmrB, MdtD, and YieQ. MDR transporters are drug/H+ antiporters (DHA) that mediate the efflux of a variety of drugs and toxic compounds, and confer resistance to these compounds. For example, MMR confers resistance to the epoxide antibiotic methylenomycin. This subfamily belongs to the Methylenomycin A resistance protein (also called MMR peptide) and similar multidrug resistance (MDR) transporters (MMR-like MDR transporter) family of the Major Facilitator Superfamily (MFS) of transporters. MFS proteins are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	1.30299e-12
NC_011835.1\|WP_004218731.1\|917199_919899_-\|aconitate-hydratase-AcnA	gnl\|CDD\|236445	PRK09277, PRK09277, aconitate hydratase AcnA.	0
NC_011835.1\|WP_004218730.1\|919966_922537_-\|HAD-IC-family-P-type-ATPase	gnl\|CDD\|319795	cd02609, P-type_ATPase, uncharacterized subfamily of P-type ATPase transporter, similar to uncharacterized Streptococcus pneumoniae exported protein 7, Exp7. This subfamily contains P-type ATPase transporters of unknown function, similar to Streptococcus pneumoniae Exp7. The P-type ATPases, are a large family of integral membrane transporters that are of critical importance in all kingdoms of life. They generate and maintain (electro-) chemical gradients across cellular membranes, by translocating cations, heavy metals and lipids. They are distinguished from other main classes of transport ATPases (F- , V- , and ABC- type) by the formation of a phosphorylated (P-) intermediate state in the catalytic cycle. A general characteristic of P-type ATPases is a bundle of transmembrane helices which make up the transport path, and three domains on the cytoplasmic side of the membrane. Members include pumps that transport various light metal ions, such as H(+), Na(+), K(+), Ca(2+), and Mg(2+), pumps that transport indispensable trace elements, such as Zn(2+) and Cu(2+), pumps that remove toxic heavy metal ions, such as Cd(2+), and pumps such as aminophospholipid translocases which transport phosphatidylserine and phosphatidylethanolamine.	0
NC_011835.1\|WP_004269164.1\|911658_912990_+\|ABC-transporter-substrate-binding-protein	gnl\|CDD\|379175	pfam13416, SBP_bac_8, Bacterial extracellular solute-binding protein. This family includes bacterial extracellular solute-binding proteins.	6.06288e-36
NC_011835.1\|WP_004219444.1\|897748_899083_-\|hypothetical-protein	gnl\|CDD\|235057	PRK02628, nadE, NAD synthetase; Reviewed.	1.98464e-35
NC_011835.1\|WP_004219367.1\|908014_908431_-\|DUF4235-domain-containing-protein	gnl\|CDD\|379422	pfam14019, DUF4235, Protein of unknown function (DUF4235). This family of integral membrane proteins is functionally uncharacterized. This family of proteins is found in bacteria. Proteins in this family are typically between 88 and 119 amino acids in length.	8.57425e-16
NC_011835.1\|WP_004269239.1\|890439_891453_+\|ribose-phosphate-diphosphokinase	gnl\|CDD\|179535	PRK03092, PRK03092, ribose-phosphate diphosphokinase.	0
NC_011835.1\|WP_004219087.1\|891590_892559_-\|ribokinase	gnl\|CDD\|238579	cd01174, ribokinase, Ribokinase catalyses the phosphorylation of ribose to ribose-5-phosphate using ATP. This reaction is the first step in the ribose metabolism. It traps ribose within the cell after uptake and also prepares the sugar for use in the synthesis of nucleotides and histidine, and for entry into the pentose phosphate pathway. Ribokinase is dimeric in solution.	9.76109e-100
NC_011835.1\|WP_004219452.1\|899117_899654_-\|NAD+-synthetase	gnl\|CDD\|235057	PRK02628, nadE, NAD synthetase; Reviewed.	8.91366e-57

>NC_011835.1|WP_004219371.1|906561_906813_+|hypothetical-protein
MHYFTPKRCETTTKIMYHDRQTAWQAAEQSRIERGVELWVYQCQYCGQWHLTHRDPALAQAVGHFKRSQKPYSRKKGFKPRRR
>NC_011835.1|WP_004219373.1|905925_906516_+|hypothetical-protein
MVNSQPMPAHALSLGQFPTVISRNLNLSIIATGIMAFVGILTETMTNVLLPVLMGLFTVSTATVQWLTTGYLLMVAVVISVSSYCNRRFTNRATFIIAMVLCIAALAAIAPTLHADSNAVFNTLQQLGGVVGTTVMALCLSIVQFGHGEVGSRDYMEATKQGGEWALIVVSVFVFVAILANLRAFLNERRQNVRMR
>NC_011835.1|WP_004219452.1|899117_899654_-|NAD+-synthetase
MIMNNGFVPVATASPNTRVADPMANAELCCDAIVRAANAGAKVVALPEVVLTSYIADDMLCHDIVLGAAEETLAHLVAETAKLDVVFSVGLPLCVNGKIYNTLAICHAGEIMGVVPKTYIPTYGVDFEGRWFSSGPADVTYITVAGQEHVPFGSHQVFRCCQMPQLCLGYEICEDIWA
>NC_011835.1|WP_004219444.1|897748_899083_-|hypothetical-protein
MIICNGPASNASLEKDLYRRSLISGQSARLLCCYAYCSSGQGDSTGDVTVGGQEIIAENGSILAQSEPFGDGFAVADVDVESLWGARRGMSSFHVEPTPQYADYHETMFDMTIPDHPLMRPVSKQPFIPADEKMRADCCSLAVTMQAHGLAARVGAQNADHLVIDTTNSSVTNTALAVLAVARFYDLERPAVPDMYVAISQDAQNGQSANVKLIEQLADALGLPLATLASARAEQQNAAQSSPEHPVLDIQELIGDTSWLIVNPSDMTQLALGLTQFPFDLGRQYGINSQIAHTFVPVIPRQYAQECADGNLQTLLGAICDPDNELHIPEHDTVSMSESAELGPAVVEDFYLDGFLRAQYRPAKTFALARQAFAGEYGEHELPGWMKAFYERFFGSQFLRHSLPDGPRIGSAGLDLRDGFMMPTYAQSTLWMNEVDALLNAATK
>NC_011835.1|WP_004219443.1|897314_897584_+|type-II-toxin-antitoxin-system-RelB/DinJ-family-antitoxin
MNMTSVTVRVDEDTKKQASDIAEDFGFDLSSVTRAFYRQIVRERRIPLNLSYSNVPEETLEALAEARRMAKEGAPRFQDADAMFDSLGI
>NC_011835.1|WP_012619808.1|895358_896405_-|LacI-family-DNA-binding-transcriptional-regulator
MVRRVTLREVAQEAQVSVATASLVLNNKPSRISQPTQQRIRDVARRLHYVVNENARGLVTNETRLIALIVPDIENMFFASLSKCLETECRRNGYQLFISNSDDDRTLERRLMRNFVGRDIDGLLLIPSIDSYTDRALLRDQICASPCPIVIIDRLITADICDGVGFDNELGGRLAAKKLLCAGHRRFACITGNKDSVNANTRCYGFLKTLQEHEVPADSILTLDGNYRFSGGYDAADAVADFGATCLFCCNDLMALGAIDRFRELGIAIPADISIIGYDNIVKRFGLLTRLTTVEQNVSELASQSWQCLYRHIQHHDSGRNCAEANDLLLLEPQLVEGDTVAQAPIFR
>NC_011835.1|WP_004219085.1|894222_895176_-|nucleoside-hydrolase
MKKLILDLDTGVDDALAISYALGSPEVELIGITGTYGNVLMEQGVRNALAITELLGHPEVPVYKGLPHASTKDSFEVLPISAFIHGENGIGDAVIPDPQRDAETEPAVDFIIDAVKTYGDDLVYVPTGPQTNIAAAFRKAPEIAEQLGKIVLMGGALTVPGNVNAWTEANISQDPDAADYVFRHTKDATMIGLDVTLQTLLTYKETQRWRDLGNAAGTFLADMTDFYIKAYETTAPHLGGCGLHDPLAVGVAVDPTLVTVHPINMKVDVEGPTRGRTIGDEDRLNDPHKTMGAALDVDVPRFLDEFMTRITNVAKNA
>NC_011835.1|WP_004219086.1|892661_894140_-|MFS-transporter
MTAPNNTAVVQEEPVDLEQQNKMAVRALILLLITFILGTLCLQGFNLVFTNIGSDVGAPEQAALITSLPSIVLGIVCFIYGSLGDFVSLKKLIVFGLVTLFVGSLFGFIANFFFTKNLWTVIIARILQTAGEQVSGSVYLVIATKYLKKELKVIFFGLFTAGYQVSAAIGVFAAGLLTSIAWQYLFLIPAVTIVFLPFLLHLLPNRRGGSQHVDWLGFTIFGLASAFLSLFFSYNSWWMLAVCVVLFVLFGVYINKASDPFITPAFFKNTRWLAAIMLIVLFYFTNYCVSPIFNTMGTTLYNMDVTQVSQYIVWAFIVAAVFGTTSGWIVGKIGRTTAIVLASLLMICGFVGSALCVNTDFGLLTLFACIFYAGCGLMYSPVVSTVLDTLPVDESGRGVGMNDLVMNVTASIGIAVFGAQLGGTALAGGSLTGATGPAAVYSNLLIIAAGVVVLGLVWFLVFHKHIYRGESAQVQKEVEQPEDVEEVLHPAK
>NC_011835.1|WP_004219087.1|891590_892559_-|ribokinase
MNQILDKLEQIHGSVSVVGSMNADYTVTTERLPGPGETVTGGPLQVLPGGKSGNQAAAAAKLGATVRMFGAVGSDSNADFLLTQLASAGVNTDGIRKVLGPSGTTVITVDSHGENTIVYSPGSNANVTVEYIESQRDLLTASSVLGLCLESPLETVTACATMCHDAGMKVLLNDSPFIATLPSELIAHADILLVNEHELVQLLHIDEPEDDDWDSFDWAQAQNRLSEFGFDQAIVTLGGDGSVVLDSTVDPSIIRIAPVRVDAVDTTGCGDSFMGTVLASLASGLSLEESAQLASYVSAYAATGYGAQASYGTAAQIRERFR
>NC_011835.1|WP_004269239.1|890439_891453_+|ribose-phosphate-diphosphokinase
MSAVLEGTPDKRLALVTGRAYPEQATETAHYLGTEVLPTTAYDFANGEMYVRYTEPIRGADVFIMQAHTQPINKWIMEQLIMIDAAKRASARSITVVAPFFGYSRQDKKHLGREPITAKLMFTLMRAAGADRVMTVDLHAAQEQGFFNGPVDHLTAMPILLDYMRDRLPLDNTTIVSPDAGRIKVSEQWAAKLGGLPLAFIHKTRDTTRPNHAEAHGIIGEVKDRDCVVIDDMIDTAGTICEAVRTLHDHGAKSVTLVATHGLLSGPAVERLKDSGVKEIVLTDTVPIPEEKRLPNMTVLSAAPLLAAGIRSVFESRSVSNLLNGLPEDMHTRHIYA
>NC_011835.1|WP_004219369.1|907138_907915_-|nitroreductase-family-protein
MAKIIHNDTVDVLLERVSIRAFKDEAIGLDVLNTIEQAAQNTASSQYLNDWSAIRIKDPAVKTEIARICNQDYIANAPVLYIFVLDQYRNSLIAQSEGVAVDSDEFTLKNSYRFSQAQNDAVLALHAMETAAESFELGTVILGSILGNIPELVKLLALPKYTYPVLGLALGKPDQHPDPKPRLPRDIQFFDDSYNAEPNRILDGIREYDREVQAYYDTRGKDLSERAYSDMTTKKATSTAALEMGFEHARAQGFDLEK
>NC_011835.1|WP_004219367.1|908014_908431_-|DUF4235-domain-containing-protein
MATAKPVQSAHTRDTNEKLANLDNTTKETVQRIDKVNNKITDLREQRMRDPDTLGDKAFKLAFPALIGMVAGKAFQSVWNLVTNKVHPSPNDDEADRKQGLLMSVLFAAASAAFSTVVTTYSDKLTQSIVGRLQRKRK
>NC_011835.1|WP_004219365.1|908593_909262_+|histidine-phosphatase-family-protein
MESAGKLVLLRHGQTVWSQSGQYTGRTNIPLTPVGREQAAAAGERLRATFPNGFTPSNIYTSDLARAMETAELAGFAEHNVTADLEEWDYGRAEGRTREQLNAAAGYEWNVWRDGPHSLDETLSGTRVEVFEDGSEITVVNGEGEALEDAAARTRTVIEQVLPALLAGENVLLVAHAHILRILTSQWLDLAPDFGRKLHLDTAHYSVLGIYKGDHVIYSWNS
>NC_011835.1|WP_004219382.1|909524_911300_-|glycoside-hydrolase-family-13-protein
MTANNMHDDWWKQAVVYQVYPRSFRDANGDGLGDIAGITEQVPYLKHLGVDAIWLSPFYPSELADGGYDVIDYRNVDPRLGTLEDFDELVTALHAHGMKIVVDIVPNHTSNMHEWFQAALTAEPGSPERDRYIFREGRGEHGELPPNDWQSLFGGPAWQRVADGQWYLHIFTVEQPDLNWKNPEVHEDFKKTLRFWSDRGVDGFRIDVAHGLAKDLDSKPLAEMDADCVFDTDNRNGNNPLWDRAEVHDIYREWNAVFNEYRPARFAVGEAWVIPEHQHLYAREGELGQVFNFEFAKANWNAAAFKVAIEDGIRSAHDAESTTTWVMSNHDVVRHASRYGLPQVPTTGYHELPNDWLLRDGTTYIEDRDLGARRARAAILMELGLPGSVYVYQGEELGLPEVANIPWNHLEDPIAFHTDHAGAQKGRDGCRVPLPWRADDEPRPADWDPLFGTGASFGFSDAPADGSAPADPHLPQPLWYKQYAADKQMADDTSMFNLYRQAMQFRQEHLTPSDDTDDITWLPGTDFNAHNAEVVAYTRPCTGEGDGTFACIVNFGPDPIDLPAGTVVLSSEPLDEPHKLSADTAVWMLLP
>NC_011835.1|WP_004269164.1|911658_912990_+|ABC-transporter-substrate-binding-protein
MNRTVKATVGLVAIAAMSLTGLAACGGSSADDGKGKVYFLNFKPEAADQWVALAKKYTDKTGVQVKVQTAASGTYEQTLKSELAKSDAPTIFQVNGPVGYQNWKGYTADLKDTGIYNELNNKDIALKDGDKVVGIPYVMETYGIIYNKDLLKKYTELPGAKIKDVKEIDSFDKLKEVADDMQAKKDQLGIKGAFTSAGFDSSSDWRFKTHLANIPLSYEFKEDGVTTQPETIKGTYLPNFKNIFDLYLKDSTTAPSQLSSKTGDDANSEFALGEAAFYQNGTWAWTDLQKAGMKPDQVGMLPIYIGAKGEENQGLATGSENYLCINAKASEADQKASKDFLNWVVTSDEGIKALSEDMGFTTPFKTFDKVKSDNPLVEEAVEDSNSGKEQVAWNFTMMPSEEWKNQLGQAMLAYAQGNGSWDDVQKAFVDNWKTEYDNAHANQ
>NC_011835.1|WP_193338208.1|913249_914545_-|ISL3-like-element-IS2001-family-transposase
MFDPQRFLGLDEMGLRVLSWRRLGRPDGPGLRQIRCEPDSHDARWCPSCGAYARVRSSWLRTLAHVPYGDDAVHLLVRVRRYECVPCSRSWSDDPEAVGAGRGVLSVPAVMWALRRVCLDSMTVSACARLLHVAWAVVDRAVRERGMLLLEQADRFSSVRAIGVDEHVWRHGAFGDRYVTVIVDLTPRCDGRPARLLDMVPGRSAQVLREWMQARGGEFTRRVGVVAMDAFAGWKQAVESVVPHAVEVIDPFHVVQLAAARVTRVRCRLQRDATGRRGVKGDRLYDCRRALLTSDEYLGARGRARLMALFAIQANRDLMLAHDAYQRVIHAYRCDDGRRGERMMRELIDDLTGPGRYKGCRELASLGRVLKRRMRDILALFRHPRSSNGPTEAINGRLETLRGNAMGFANTTSYIQRCLIHSSQLKDILTH
>NC_011835.1|WP_004218733.1|916050_916692_-|sugar-O-acetyltransferase
MTNGTSADTREYERMLSGELYIADDPYLKEHSLKRRRLVQEINRSDYDEFDKREALFRELFGSFGEGSYIEPPFRADYGCNTYIGRNFYANTDCIFLDVARIDIGDNVFCGPRVSLLTPYHPIDAQVRNEQLEGGKPISIGNDVWFGGNVTVCPGVTIGDDVVIGAGSVVVKDIPSHCIAVGNPCRPIRAITDADHEQWQRKAREYRAWKEGI
>NC_011835.1|WP_004218732.1|916864_917116_+|hypothetical-protein
MTLLWSSLFTIIVVGLALWVLYYIIRAAVSAGIKDAYAQMGFIREPDTKEDQLQRRREELQEERVQTIVNSEADRMSGKNGKH
>NC_011835.1|WP_004218731.1|917199_919899_-|aconitate-hydratase-AcnA
MSLRDEQLDVLKVGDKSYDYYRIADLEGVDHLPYSLKVLVENLVRNIDGANITDEQVRELLAWDPAADPSHEIQFIPSRVVMQDFTGVPCVVDLATMRDAVKSLGGDPEVINPQVQSDMIIDHSVQIDAYGVENAVEINMDIEYQRNGERYRFLRWGQQAFENFRVVPPGTGIIHQVNIEYLAQVVMRKELSKGTTLAYLDSCVGTDSHTTTVNGLGVLGWGVGGIEAEAAMLGQPISMLVPRVVGFKLTGSIPEGVTATDVVLTITDLLRRHGVVGKFVEFYGEGIASVPLANRATIGNMSPEFGSTCGIFPIDEVTLDYLRLTGRSEEQVALVEAYAKANKLWHDVNDPNFVEPSYSEYLELDLSTVVPSIAGPKRPQDRIELSHAKTTFEQTLPGYITEKTNGNPVPVSTDFRGDFELTNGDVAIASITSCTNTSNPSVMIAAGLIARNAVAKGLKPKPWVKTSLAPGSQVVADYLKQAGLQDDLDRLGYELVGFGCATCIGNSGPLLPEISEAINANDLTVTAVLSGNRNFEGRISPDVKMNYLASPPLVIAYALAGTMDFDFEHEALGKDPEGNDVYLKDIWPTNAEVEQVVSGNVSREMFLNDYASVFEGDSRWKGLDVPEGELFAWNPESTYVRKQTFFDGMSATPAPVEDIRDARVLALLGDSVTTDHISPAGAFKASSPAGKYLVEHGVEPKNFNSYGSRRGNHEVMVRGTFGNIRLRNMLLASVGEEVRPGGYTYDFLAMKPTTIYEASRDYIDNGVPLVVLGGKEYGTGSSRDWAAKGTAMLGVKAVIVESFERIHRSNLIGMGVLPLQFPEGESAESLGLDGTETYSITGITELNNGVTPKSVHVEATHKDGSKTEFEAVVRIDTPGEADYYRNGGILQYVLRNLMK
>NC_011835.1|WP_004218730.1|919966_922537_-|HAD-IC-family-P-type-ATPase
MSDSANAQQSVSMTGAQGGDDHAHMPDVTEKGLTAAEVRDRVERGQTNEVKSSTSRSLADIVRANVFTLFNGIIFTAMVMVLITGSWKDAVFGLVILINTGIGIVTELRAKRTLDKLSILIASDYLVRRDGKDVDVPHNGIVLGDCLWIRSGEQIPCDAEILHTWGLELDESMITGESRTVRKQEGETVYSGSTAVSGMALVKVTAVGAHSYAATLTAQAKVYKKNVSDLNKGINTILKFMTFLVVPLCMLLIVTQMRTVGGWHNAIATGEWRQAVVSSVAGVVGMVPEGLVLLTSLNFALAAIRLARKNTLVQDLDSVETLARVDALNLDKTGTITDGGIVYDDFIALPGCRNKQHAMQALYDLANEESPNGTGRAVLEGLGKQGFSGSAGLVRVPFSSARKWSAVAFHGLPDEGQNGVWYMGAPEVLLSGFDGEYQQILAQVNEYANNGNRVLLIAHVPGGDVPADFETNPQLERTAVPVAIVLCSEHIRSDAEPTLRWFREQGVRCRVISGDNPVTVGAIAAKVQLTGERKPVAMDARELPKNVDELARVLEGVDVLGRVLPEQKKAIVQALHTQDHVVAMTGDGVNDALAIKEADLGIAMGNAAPATKAVAEVVLVDSKFSHLPDVVARGRQVMANMERVASLFVTKTAYSALISLGVVLMGIPFPYLPRHISYIGALTIGAPAFFLALAPNTRRYIPGFLRRVVAFSVPCGIATGLSVLLSAWFIPRFMHWNVFTSEQQLFWLRSMCATVLFLMGIYVLSRVSKPLNSWRGWLVLAFAAAGVIGACIPFIARFFAFGLPAGRAVWILLLQMAVATVLFVISIWVFSRFLPKWMREAGRETGINGASHNTNG

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Crispr_ID: NC_011835_5

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_011835_5

928474-928659

Orphan

Consensus_repeat	Method
TTGCGTAAAAAGAGACAGA	PILER-CR

2 spacers

The CRISPR arrays of NC_011835_5

>merge|NC_011835|5|928474-928659|PILER-CR
TTGCGTAAAAGGAGACAGATTAAGCAAGAATCTGTCCCTTTTACGCATGATTATCTCGTGTGTGAACACCTTGTGTGCAAGTGCCCCTCAGCGTAATCAGCGTAAAAAGAGACAGTTCCGGTAAGGAAATTGTCTCCGATTACGCAACTAACCGTATGCACTCCCGTTTGCGTAAAAAGAGACAGA

>NC_011835|5|2|928474-928659|PILER-CR
TTGCGTAAAAGGAGACAGA	TTAAGCAAGAATCTGTCCCTTTTACGCATGATTATCTCGTGTGTGAACACCTTGTGTGCAAGTGCCCCTCAGCGTAAT
CAGCGTAAAAAGAGACAGT	TCCGGTAAGGAAATTGTCTCCGATTACGCAACTAACCGTATGCACTCCCGT
TTGCGTAAAAAGAGACAGA

Protein	Signature genes	Signature genes Name	Protein_function
NC_011835.1\|WP_004218724.1\|927796_928471_+\|membrane-protein	unknown	unknown	unknown
NC_011835.1\|WP_004218727.1\|924932_925703_-\|DUF3159-domain-containing-protein	unknown	unknown	gnl\|CDD\|371490
NC_011835.1\|WP_004218721.1\|931760_932687_-\|ABC-transporter-permease	unknown	unknown	gnl\|CDD\|223674
NC_011835.1\|WP_004218708.1\|941241_942357_-\|chorismate-mutase	unknown	unknown	gnl\|CDD\|270350
NC_011835.1\|WP_004218732.1\|916864_917116_+\|hypothetical-protein	unknown	unknown	unknown
NC_011835.1\|WP_004218718.1\|934904_935840_-\|tyrosine-recombinase-XerC	unknown	unknown	gnl\|CDD\|234698
NC_011835.1\|WP_004218726.1\|925771_926629_-\|DUF3710-domain-containing-protein	unknown	unknown	gnl\|CDD\|378867
NC_011835.1\|WP_012619816.1\|936892_939727_+\|FtsX-like-permease-family-protein	unknown	unknown	gnl\|CDD\|226957
NC_011835.1\|WP_004218716.1\|936078_936885_+\|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|224059
NC_011835.1\|WP_004218710.1\|939871_940123_+\|hypothetical-protein	unknown	unknown	unknown
NC_011835.1\|WP_004269170.1\|926762_927623_-\|endonuclease/exonuclease/phosphatase-family-protein	unknown	unknown	gnl\|CDD\|197336
NC_011835.1\|WP_004218729.1\|922585_923173_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|380532
NC_011835.1\|WP_004218720.1\|932987_934628_-\|ABC-transporter-substrate-binding-protein	unknown	unknown	gnl\|CDD\|173853
NC_011835.1\|WP_004218731.1\|917199_919899_-\|aconitate-hydratase-AcnA	unknown	unknown	gnl\|CDD\|236445
NC_011835.1\|WP_004218709.1\|940138_941233_-\|prephenate-dehydrogenase/arogenate-dehydrogenase-family-protein	unknown	unknown	gnl\|CDD\|235824
NC_011835.1\|WP_004218728.1\|923508_924819_-\|class-I-SAM-dependent-RNA-methyltransferase	unknown	unknown	gnl\|CDD\|225174
NC_011835.1\|WP_004218730.1\|919966_922537_-\|HAD-IC-family-P-type-ATPase	unknown	unknown	gnl\|CDD\|319795
NC_011835.1\|WP_004218722.1\|930790_931747_-\|ABC-transporter-permease	unknown	unknown	gnl\|CDD\|224094
NC_011835.1\|WP_004218733.1\|916050_916692_-\|sugar-O-acetyltransferase	unknown	unknown	gnl\|CDD\|100047
NC_011835.1\|WP_089194267.1\|928730_930719_-\|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|224048

Protein	Function_ID	Function_description	E-value
NC_011835.1\|WP_004218727.1\|924932_925703_-\|DUF3159-domain-containing-protein	gnl\|CDD\|371490	pfam11361, DUF3159, Protein of unknown function (DUF3159). Some members in this family of proteins with unknown function are annotated as membrane proteins however this cannot be confirmed. Currently this family of proteins has no known function.	7.39971e-73
NC_011835.1\|WP_004218721.1\|931760_932687_-\|ABC-transporter-permease	gnl\|CDD\|223674	COG0601, DppB, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism].	2.47608e-107
NC_011835.1\|WP_004218708.1\|941241_942357_-\|chorismate-mutase	gnl\|CDD\|270350	cd13632, PBP2_Aa-PDT_like, Catalytic domain of prephenate dehydratase from Arthrobacter aurescens and similar proteins, subgroup 3; the type 2 periplasmic binding protein fold. Prephenate dehydratase (PDT, EC:4.2.1.51) converts prephenate to phenylpyruvate through dehydration and decarboxylation reactions. PDT plays a key role in the biosynthesis of L-Phe in organisms that utilize the shikimate pathway. PDT is allosterically regulated by L-Phe and other amino acids. The catalytic PDT domain consists of two similar subdomains with a cleft in between, which hosts the highly conserved active site. In gram-postive bacteria and archaea, PDT is a monofunctional enzyme, consisting of a catalytic domain (PDT domain) and a regulatory domain (ACT) (aspartokinase, chorismate mustase domain). In gram-negative bacteria, PDT exists as fusion protein with chorismate mutase (CM), forming a bifunctional enzyme, P-protein (PheA). The CM in the P-protein catalyzes the pericycle isomerization of chorismate to prephenate that serves as a substrate for PDT. The CM and PDT are essentail enzymes for the biosynthesis of aromatic amino acids in microorganisms but are not found in humans. Thus, both CM and PDT can potentially serve as drug targets against microbial pathogens. The PDT domain has the same structural fold as the type 2 periplasmic binding proteins (PBP2), many of which are involved in chemotaxis and uptake of nutrients and other small molecules from the extracellular space as a primary receptor. The PBP2 proteins are typically comprised of two globular subdomains connected by a flexible hinge and bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap.	3.50315e-48
NC_011835.1\|WP_004218718.1\|934904_935840_-\|tyrosine-recombinase-XerC	gnl\|CDD\|234698	PRK00236, xerC, site-specific tyrosine recombinase XerC; Reviewed.	1.25243e-141
NC_011835.1\|WP_004218726.1\|925771_926629_-\|DUF3710-domain-containing-protein	gnl\|CDD\|378867	pfam12502, DUF3710, Protein of unknown function (DUF3710). This family of proteins is found in bacteria. Proteins in this family are typically between 237 and 284 amino acids in length. There are two conserved sequence motifs: DLG and DGPRW.	1.21457e-62
NC_011835.1\|WP_012619816.1\|936892_939727_+\|FtsX-like-permease-family-protein	gnl\|CDD\|226957	COG4591, LolE, ABC-type transport system, involved in lipoprotein release, permease component [Cell envelope biogenesis, outer membrane].	2.14759e-23
NC_011835.1\|WP_004218716.1\|936078_936885_+\|ABC-transporter-ATP-binding-protein	gnl\|CDD\|224059	COG1136, SalX, ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms].	7.2024e-112
NC_011835.1\|WP_004269170.1\|926762_927623_-\|endonuclease/exonuclease/phosphatase-family-protein	gnl\|CDD\|197336	cd10281, Nape_like_AP-endo, Neisseria meningitides Nape-like subfamily of the ExoIII family purinic/apyrimidinic (AP) endonucleases. This subfamily includes Neisseria meningitides Nape and related proteins. These are Escherichia coli exonuclease III (ExoIII)-like AP endonucleases and belong to the large EEP (exonuclease/endonuclease/phosphatase) superfamily that contains functionally diverse enzymes that share a common catalytic mechanism of cleaving phosphodiester bonds. AP endonucleases participate in the DNA base excision repair (BER) pathway. AP sites are one of the most common lesions in cellular DNA. During BER the damaged DNA is first recognized by DNA glycosylase. AP endonucleases then catalyze the hydrolytic cleavage of the phosphodiester bond 5' to the AP site, and this is followed by the coordinated actions of DNA polymerase, deoxyribose phosphatase, and DNA ligase. If left unrepaired, AP sites block DNA replication, and have both mutagenic and cytotoxic effects. AP endonucleases can carry out a variety of excision and incision reactions on DNA, including 3'-5' exonuclease, 3'-deoxyribose phosphodiesterase, 3'-phosphatase, and occasionally, nonspecific DNase activities. Different AP endonuclease enzymes catalyze the different reactions with different efficiences. Many organisms have two AP endonucleases, usually one is the dominant AP endonuclease, the other has weak AP endonuclease activity; for example, Neisseria meningitides Nape and NExo. Nape, found in this subfamily, is the dominant AP endonuclease. It exhibits strong AP endonuclease activity, and also exhibits 3'-5'exonuclease and 3'-deoxyribose phosphodiesterase activities.	8.13408e-110
NC_011835.1\|WP_004218729.1\|922585_923173_-\|hypothetical-protein	gnl\|CDD\|380532	cd06309, PBP1_galactofuranose_YtfQ-like, periplasmic binding domain of ABC-type galactofuranose YtfQ-like transport systems. Periplasmic binding domain of ABC-type YtfQ-like transport systems. The YtfQ protein from Escherichia coli is up-regulated under glucose-limited conditions and shares homology with a family of pentose/hexose sugar-binding proteins of the type 1 periplasmic binding protein superfamily. Members of this group are predicted to be involved in the transport of sugar-containing molecules across cellular and organellar membranes; however their ligand specificity is not determined experimentally.	0.000557278
NC_011835.1\|WP_004218720.1\|932987_934628_-\|ABC-transporter-substrate-binding-protein	gnl\|CDD\|173853	cd00995, PBP2_NikA_DppA_OppA_like, The substrate-binding domain of an ABC-type nickel/oligopeptide-like import system contains the type 2 periplasmic binding fold. This family represents the periplasmic substrate-binding domain of nickel/dipeptide/oligopeptide transport systems, which function in the import of nickel and peptides, and other closely related proteins. The oligopeptide-binding protein OppA is a periplasmic component of an ATP-binding cassette (ABC) transport system OppABCDEF consisting of five subunits: two homologous integral membrane proteins OppB and OppF that form the translocation pore; two homologous nucleotide-binding domains OppD and OppF that drive the transport process through binding and hydrolysis of ATP; and the substrate-binding protein or receptor OppA that determines the substrate specificity of the transport system. The dipeptide (DppA) and oligopeptide (OppA) binding proteins differ in several ways. The DppA binds dipeptides and some tripeptides and is involved in chemotaxis toward dipeptides, whereas the OppA binds peptides of a wide range of lengths (2-35 amino acid residues) and plays a role in recycling of cell wall peptides, which precludes any involvement in chemotaxis. Similar to the ABC-type dipeptide and oligopeptide import systems, nickel transporter is comprised of five subunits NikABCDE: the two pore-forming integral inner membrane proteins NikB and NikC; the two inner membrane-associated proteins with ATPase activity NikD and NikE; and the periplasmic nickel binding NikA, which is the initial nickel receptor that controls the chemotactic response away from nickel. Most of other periplasmic binding proteins are comprised of only two globular subdomains corresponding to domains I and III of the dipeptide/oligopeptide binding proteins. The structural topology of these domains is most similar to that of the type 2 periplasmic binding proteins (PBP2), which are responsible for the uptake of a variety of substrates such as phosphate, sulfate, polysaccharides, lysine/arginine/ornithine, and histidine. The PBP2 bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap. After binding their specific ligand with high affinity, they can interact with a cognate membrane transport complex comprised of two integral membrane domains and two cytoplasmically located ATPase domains. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis. Besides transport proteins, the PBP2 superfamily includes the ligand binding domains of ionotropic glutamate receptors, LysR-type transcriptional regulators, and unorthodox sensor proteins involved in signal transduction.	5.09772e-137
NC_011835.1\|WP_004218731.1\|917199_919899_-\|aconitate-hydratase-AcnA	gnl\|CDD\|236445	PRK09277, PRK09277, aconitate hydratase AcnA.	0
NC_011835.1\|WP_004218709.1\|940138_941233_-\|prephenate-dehydrogenase/arogenate-dehydrogenase-family-protein	gnl\|CDD\|235824	PRK06545, PRK06545, prephenate dehydrogenase; Validated.	1.78829e-64
NC_011835.1\|WP_004218728.1\|923508_924819_-\|class-I-SAM-dependent-RNA-methyltransferase	gnl\|CDD\|225174	COG2265, TrmA, SAM-dependent methyltransferases related to tRNA (uracil-5-)-methyltransferase [Translation, ribosomal structure and biogenesis].	3.30445e-81
NC_011835.1\|WP_004218730.1\|919966_922537_-\|HAD-IC-family-P-type-ATPase	gnl\|CDD\|319795	cd02609, P-type_ATPase, uncharacterized subfamily of P-type ATPase transporter, similar to uncharacterized Streptococcus pneumoniae exported protein 7, Exp7. This subfamily contains P-type ATPase transporters of unknown function, similar to Streptococcus pneumoniae Exp7. The P-type ATPases, are a large family of integral membrane transporters that are of critical importance in all kingdoms of life. They generate and maintain (electro-) chemical gradients across cellular membranes, by translocating cations, heavy metals and lipids. They are distinguished from other main classes of transport ATPases (F- , V- , and ABC- type) by the formation of a phosphorylated (P-) intermediate state in the catalytic cycle. A general characteristic of P-type ATPases is a bundle of transmembrane helices which make up the transport path, and three domains on the cytoplasmic side of the membrane. Members include pumps that transport various light metal ions, such as H(+), Na(+), K(+), Ca(2+), and Mg(2+), pumps that transport indispensable trace elements, such as Zn(2+) and Cu(2+), pumps that remove toxic heavy metal ions, such as Cd(2+), and pumps such as aminophospholipid translocases which transport phosphatidylserine and phosphatidylethanolamine.	0
NC_011835.1\|WP_004218722.1\|930790_931747_-\|ABC-transporter-permease	gnl\|CDD\|224094	COG1173, DppC, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism].	1.74143e-86
NC_011835.1\|WP_004218733.1\|916050_916692_-\|sugar-O-acetyltransferase	gnl\|CDD\|100047	cd03357, LbH_MAT_GAT, Maltose O-acetyltransferase (MAT) and Galactoside O-acetyltransferase (GAT): MAT and GAT catalyze the CoA-dependent acetylation of the 6-hydroxyl group of their respective sugar substrates. MAT acetylates maltose and glucose exclusively at the C6 position of the nonreducing end glucosyl moiety. GAT specifically acetylates galactopyranosides. Furthermore, MAT shows higher affinity toward artificial substrates containing an alkyl or hydrophobic chain as well as a glucosyl unit. Active MAT and GAT are homotrimers, with each subunit consisting of an N-terminal alpha-helical region and a C-terminal left-handed parallel alpha-helix (LbH) subdomain with 6 turns, each containing three imperfect tandem repeats of a hexapeptide repeat motif (X-[STAV]-X-[LIV]-[GAED]-X).	2.64242e-97
NC_011835.1\|WP_089194267.1\|928730_930719_-\|ABC-transporter-ATP-binding-protein	gnl\|CDD\|224048	COG1123, COG1123, ATPase components of various ABC-type transport systems, contain duplicated ATPase [General function prediction only].	0

>NC_011835.1|WP_004218724.1|927796_928471_+|membrane-protein
MTKPTDSPAAKLPMPRGFKLFIALAVLMVVGAAISLFDKSEFYADVFIEISVFCVFLAGFFTNTRTLQFAYLVGANIYVIVCLGAFSTVFFTKMNQGVGVLLIIQIIFSCLNLVPIIIYHLTDREFFYTYQRQLIYPTLFFVFVLLGHLPGGDVLTSEVSHEIFSLIIFAQAFEIMDAIHKVGKAHHMAAYAINTQPLGTKLVPDTDDADDSEGSLDEPEDVEE
>NC_011835.1|WP_004269170.1|926762_927623_-|endonuclease/exonuclease/phosphatase-family-protein
MALTITTSNLNGIRAAKRKGFDHWAKAHTPNVWCMQETRAPQEIIADIYGELAADYVHAGKIASPEELHTLVDVCRIKGRAGVGMISDMPVLETRVGLPGLEEDVDSGRWIEADVRTEQGYVITVVCVYVHAGGLVDDPKEAQKYRFLDTMTERMQQLQDEAASGGRQAVVCGDFNIAHNPIDLKNPKSNENNNGYFPRERAYMDKWIDQMDYVDVMRDLAGDIQGPYTWWSQRGRAFDNDSGWRLDYQFATPELAQQARGFVVDRASSYDSRWSDHAPLTISYDV
>NC_011835.1|WP_004218726.1|925771_926629_-|DUF3710-domain-containing-protein
MGLFGFGRKKKKQQDDERLAEAVDSRTEDVAVEDSEDDEQTEVLEGARTEVGVDYEGRGETVGPWDVDDANAPDYDEYLSLGAYYLPFVQGIQLRIKANNATHEIVGATMTIGNSSLEVEAFAAPKTMGLWDDVREDLLASNPEAEAVDGIFGTEVKLPVKLPNGKTAHTRIVGVDGPRWMLRGIFSGKAASDPDGTETKILNDAFAQIVVERGDEPLSPRDPIPMARPLTPNERRALAAQEEDGDLAGDDHSKIPGRPDGPLSTDQQVEQQTTLRRGPMFSEVR
>NC_011835.1|WP_004218727.1|924932_925703_-|DUF3159-domain-containing-protein
MSNQNERHASNTRPARARSGMAALANAGENDEFSVIAAIGGVRGVVESMLPGLLFVVLFICTSDLRMTVIASAALAVVQVVVRLIQRQSVMGALGGLVAVGICLFWAWKSGEARNYYMYGFITNAAYIVLLLVSMAVRVPGLGFLVEFIRSLPTEHFKAWLSGWRSDRALYKAYARITWLWIGLFALRLIVQVPLYMTNQVGWLGTTRLVMGIPFWALAIWISYLIVADPLHRHRMLEKERESTSTEGGDAHPTAQ
>NC_011835.1|WP_004218728.1|923508_924819_-|class-I-SAM-dependent-RNA-methyltransferase
MEATVDIERYADQGRCVAHIDGRVVFVRFALPGERVRIELDEPTNRNDRFWTGEVVEVLEPSPDRVEPLWPLAAPLAMGGGAGGADLIHVSLEGQERWKEATLKDVMKRLGHVDLDDVPVYAMPGDEQAHGLHWRTRIEMVTDDEGRPSMRRRGTHVRVPIDTMPLATRAVLEVAEMNGVWDGNLPENAQIRIAVPEPRVDAEQIADPEALRKAIGRNYAIMVDGKVRHGSRALKETIMVDGKPFEYTVDAGGFWQMHREAPMVLPQYVIDQIRETPGDRAPRNGRNLVIWDLYSGSGLFTLPLATLLDDRAKLVSIEGAKDAVANARRNLRNAGIHTVQALCGDVLHTLDKDIDPQRAHPDIVVLDPPRAGAKAKVCHKIANSGAPIVVYIACDPASLARDTATLTEHGYRIHSIAAFDIYPQTHHVETVAVFVK
>NC_011835.1|WP_004218729.1|922585_923173_-|hypothetical-protein
MARRTKRLAAIACAVAALALMAGCTPKGAAVGDTQNNETYEHNHNENTGARLDVAVIGSPHGGADELVMRSLATKEFKASYTGVQQYSADPQRAADFARKAVSDAVSRHPKVIVISGLTFHDDESQWNTALANARNAGIPVVLLNPADVPGDTKLFAATFVVNDRMMDAQPMGEALRSVIFDHPHEREIVVSTRS
>NC_011835.1|WP_004218730.1|919966_922537_-|HAD-IC-family-P-type-ATPase
MSDSANAQQSVSMTGAQGGDDHAHMPDVTEKGLTAAEVRDRVERGQTNEVKSSTSRSLADIVRANVFTLFNGIIFTAMVMVLITGSWKDAVFGLVILINTGIGIVTELRAKRTLDKLSILIASDYLVRRDGKDVDVPHNGIVLGDCLWIRSGEQIPCDAEILHTWGLELDESMITGESRTVRKQEGETVYSGSTAVSGMALVKVTAVGAHSYAATLTAQAKVYKKNVSDLNKGINTILKFMTFLVVPLCMLLIVTQMRTVGGWHNAIATGEWRQAVVSSVAGVVGMVPEGLVLLTSLNFALAAIRLARKNTLVQDLDSVETLARVDALNLDKTGTITDGGIVYDDFIALPGCRNKQHAMQALYDLANEESPNGTGRAVLEGLGKQGFSGSAGLVRVPFSSARKWSAVAFHGLPDEGQNGVWYMGAPEVLLSGFDGEYQQILAQVNEYANNGNRVLLIAHVPGGDVPADFETNPQLERTAVPVAIVLCSEHIRSDAEPTLRWFREQGVRCRVISGDNPVTVGAIAAKVQLTGERKPVAMDARELPKNVDELARVLEGVDVLGRVLPEQKKAIVQALHTQDHVVAMTGDGVNDALAIKEADLGIAMGNAAPATKAVAEVVLVDSKFSHLPDVVARGRQVMANMERVASLFVTKTAYSALISLGVVLMGIPFPYLPRHISYIGALTIGAPAFFLALAPNTRRYIPGFLRRVVAFSVPCGIATGLSVLLSAWFIPRFMHWNVFTSEQQLFWLRSMCATVLFLMGIYVLSRVSKPLNSWRGWLVLAFAAAGVIGACIPFIARFFAFGLPAGRAVWILLLQMAVATVLFVISIWVFSRFLPKWMREAGRETGINGASHNTNG
>NC_011835.1|WP_004218731.1|917199_919899_-|aconitate-hydratase-AcnA
MSLRDEQLDVLKVGDKSYDYYRIADLEGVDHLPYSLKVLVENLVRNIDGANITDEQVRELLAWDPAADPSHEIQFIPSRVVMQDFTGVPCVVDLATMRDAVKSLGGDPEVINPQVQSDMIIDHSVQIDAYGVENAVEINMDIEYQRNGERYRFLRWGQQAFENFRVVPPGTGIIHQVNIEYLAQVVMRKELSKGTTLAYLDSCVGTDSHTTTVNGLGVLGWGVGGIEAEAAMLGQPISMLVPRVVGFKLTGSIPEGVTATDVVLTITDLLRRHGVVGKFVEFYGEGIASVPLANRATIGNMSPEFGSTCGIFPIDEVTLDYLRLTGRSEEQVALVEAYAKANKLWHDVNDPNFVEPSYSEYLELDLSTVVPSIAGPKRPQDRIELSHAKTTFEQTLPGYITEKTNGNPVPVSTDFRGDFELTNGDVAIASITSCTNTSNPSVMIAAGLIARNAVAKGLKPKPWVKTSLAPGSQVVADYLKQAGLQDDLDRLGYELVGFGCATCIGNSGPLLPEISEAINANDLTVTAVLSGNRNFEGRISPDVKMNYLASPPLVIAYALAGTMDFDFEHEALGKDPEGNDVYLKDIWPTNAEVEQVVSGNVSREMFLNDYASVFEGDSRWKGLDVPEGELFAWNPESTYVRKQTFFDGMSATPAPVEDIRDARVLALLGDSVTTDHISPAGAFKASSPAGKYLVEHGVEPKNFNSYGSRRGNHEVMVRGTFGNIRLRNMLLASVGEEVRPGGYTYDFLAMKPTTIYEASRDYIDNGVPLVVLGGKEYGTGSSRDWAAKGTAMLGVKAVIVESFERIHRSNLIGMGVLPLQFPEGESAESLGLDGTETYSITGITELNNGVTPKSVHVEATHKDGSKTEFEAVVRIDTPGEADYYRNGGILQYVLRNLMK
>NC_011835.1|WP_004218732.1|916864_917116_+|hypothetical-protein
MTLLWSSLFTIIVVGLALWVLYYIIRAAVSAGIKDAYAQMGFIREPDTKEDQLQRRREELQEERVQTIVNSEADRMSGKNGKH
>NC_011835.1|WP_004218733.1|916050_916692_-|sugar-O-acetyltransferase
MTNGTSADTREYERMLSGELYIADDPYLKEHSLKRRRLVQEINRSDYDEFDKREALFRELFGSFGEGSYIEPPFRADYGCNTYIGRNFYANTDCIFLDVARIDIGDNVFCGPRVSLLTPYHPIDAQVRNEQLEGGKPISIGNDVWFGGNVTVCPGVTIGDDVVIGAGSVVVKDIPSHCIAVGNPCRPIRAITDADHEQWQRKAREYRAWKEGI
>NC_011835.1|WP_089194267.1|928730_930719_-|ABC-transporter-ATP-binding-protein
MQHEVGPLLEVKDLQVDFTTDEGKPIHAVRNSSFSVYPGQWVAIVGESGSGKSTSAMACLGLLPGTGHVVGGSIKLEGQEISQYSPKQFASIRGSKMGLVPQDPMSNLNPVYRIGTQVKEALTANHMDVAHEKRSNLSKALAQADITIKSEGDETFLGSKELPELLEAAGQALVKAGVEGGKYEKRMAYFREEWVPGSETRWRVADDLIKSGVKDDDAWYIAKKYVTGSTMTDRIAGLLDEAGLPDAATRARQYPHEFSGGMRQRALIAIGLACRPELLIADEPTSALDVTVQKRILDHLQELTNSLGTAVLFITHDLGLAAERAQHIVVMYKGQVVESGPSLEVLQNPQHPYTKRLVAAAPSLASQRIISVEEKGEDATSLMDHKVDEDKLEHSDVIIDVDHLTKEFKLPRRREMFKAVDDVSFKIRRGTTLAIVGESGSGKSTVANMVLRLLEPTSGKVLYNGQDIQEFKGKSLLDFRRHVQPVFQNPYGSLDPMYSIYRSIEEPLRIHKIGDKKSRLNRVKELLDMVELPESVMARYPNELSGGQRQRIAIARAMALNPDVIVCDEAVSALDVLVQDQVLHLLNDLQAKQGLTYLFITHDLAVVRQIADDVVVMQHGKLVEHDTTDEVFLHPQQQYTKDLLDAIPGGKLELGLNLEDKA
>NC_011835.1|WP_004218722.1|930790_931747_-|ABC-transporter-permease
MTDITNKPLPGQERFVAPLDETPLLSVDNVDESAPATSMWADAWRTLRKNPMFIISGIVILFILFVAIFPGVFTRTNPNYCNLENSLDGSQPGHPFGFDLQGCDVYARVVYGARTSISVGVLTTIIVVAVGTLIGAIAGFFGGWVDAVLSRLVDIFLAIPMLLGAIVVLQMFRTSSSIWKVVLVLALFGWVSTARIARGAVLSSKNLEFNTASTALGSTPMRNLFRHILPNSVAPIIVIGTTSLGSYIVSEATLSFLGIGLPPSVVSWGGDISKAQTVLRTDPMVLFYPSLALAITVLAFIMMGDAVKDALDPKSRTA
>NC_011835.1|WP_004218721.1|931760_932687_-|ABC-transporter-permease
MGKYLLRRILQMIPVVLGTTLLVYALVFALPGDPVKAMFGDKPVNEAVAAQIRSEYNLDKPFIVQYLLFLKNALSLNFGNTFAGQPVIDEISRAFPVTLKLALMAFCFEAIFGCVFGAISGLKKGKWYDSVILIVSLLLISVPTFVTGFVGQYFLGVKGHIFPVTAGADPGFFDLLLPAMVLGSVSMAYIIRLARSEISSNIAQDYVRTARAKGMSNTAVTFRHILRNSMIPVVTYLGQDLGALMGGAMITEQIFNIHGIGYLTYQSILKGEANLVVSVVTLLTLVFVICNLIVDMLYAALDPRIRYV
>NC_011835.1|WP_004218720.1|932987_934628_-|ABC-transporter-substrate-binding-protein
MKKKTLGLIAGICSLGMMLSLSACGSNGGSSAKGSGDNIITAYNSEPQNALIPGDTNETGGGKVGQLLFANLIAFNAKGEAENEVADSIKPNADSTQYTITLKDGWKFTDGTPVTAESFTKAWSYVANAKNAQKCSSFFSSIKGYDKLQDANSLKGDEQLEGLKVKDDKTFTVDLNAPDSVFPVKIGYLAFAPLPESFYKDPKAFGEKPVGNGMYKLDSWDHGKQIVLSKNADYKGSQKVANNGVTFKIYTSPDSAYADVQAGNLDVMDTVPASNTKTFQSDPDVEPYNKAGSVIQTFTIPADLDHWKTGTEEGQLRRQALSMAINREQIVEKVLNGIGTVATDFTAPVIPGYSKDLKGSDNLKYNPTKAKELWAKADAISKYDGKLTFSFNADGGAQPIYEAVVNQVNNTLGIQASINPMPTFQEFRDAISNRTIKGAFRTAWQPDYPSAENYLYQLYDTAAANGHGSNDGDYSNKDVDKLLDQAASATDQETAIKYYHDAEEILLEQLPAFPLYYSNADGVAAKGVKNFQMDWQNQPIYEEMSK
>NC_011835.1|WP_004218718.1|934904_935840_-|tyrosine-recombinase-XerC
MDAQVLMERFIEYLRSNRGLSEHTCMAYRGDILQCLEALDAFGRGNPDDVTLDDLRMWMGRMAHTVGKTSLARKTIAVRSFFTWAYEHGMLAHNPAHALRTPKIDRNLPAVLNEDQAERLMDTVDAEAGEKNAGKSKDDALNAHAKALRDCAMLELLYATGMRVGELVGLDMGSFDWSNRTVRVLGKGNKTRVIPFGAPAQQAVEHWLHGGRPVFANGNSGNAVFIGVRGCRIDQRVVRQVVHEQAEQAGVPDISPHALRHSAATHMLDGGADLREVQEMLGHSSLQTTQRYAHVSIEQLKDRYRQAFPRA
>NC_011835.1|WP_004218716.1|936078_936885_+|ABC-transporter-ATP-binding-protein
MSKQARTVTNPDDPVVARAVDLVKTYGDTDSQVTALNHVSVEFQRGELTAIMGPSGSGKSTLMHCMAGLDVPTSGQVFVEDLEVSSMKQKQLTQLRRKEIGFIFQSFNLVPTLTAEENILLPLQIAHRPVDRDWFRKVVGVVGLENRLDHRPSQLSGGQQQRVACARAMMERPSVIFADEPTGNLDSRSSREVLGFLRQCVQDYGQSIVMVTHDPRAASFADRVLVLSDGSITQDMDHPTYDDILAVFAEHDDPDNGPVDVEPAAREA
>NC_011835.1|WP_012619816.1|936892_939727_+|FtsX-like-permease-family-protein
MFRIGLRDTKAHFRRFIMSIIAIALGVAFVVGSFCFREMLNDQVSQMMGSNSDADVYVRGATEEKQEPGGSVTSYNSTYNEISTSIIPDIENVDGVASADATMQLGNAVLLDHNGDALTTVGAPTLVIGVDQDAPWRSAHFVSGEYPQTDDEVALLEDTADKAGLKTGDTAKLIVDGEAREMTVSGVFTSPSTQLGAILILARPSFVQHVLQEEGEDTSSIQFIGVYGSKTTPLDEEAQQQLADRINKALPKSADAHAVTGDSVRDDATKSIQDQLGFIQPLILIFAAIALFVGAFIIANTFTMIVRESMRGYALLRSVGASPLQVFASVLIQAVILGLVGSGIGVLLGWGLLELIAKGMTQSGMPLSGSPTPSATDVIVGVIVGVIVTIIGATLPAKTAATAPPIQAMNETVNPEKPVRARGWIGIAMVAVGAAFWVLCYLDADKRVDWQWLKDLGSGWTLGLGAAFVVIGAIVCAPAFVAPAAKVLGWIPSKAFPVTGKLATRNIGRAKRRTANTAAALFIGVAIVSCLGVVASSMKTSVSDLVDNNVNADYVVMAASMTQPISTKAVDAVEDTEGVGASSAVSMLPTVKVTNATKTIMPTTSKVDLFTKIAPVERQDGDAAKAIENGEAVIGRTVANDEHWKIGDTIDLKSENTSVDEQATKQAYEAYQKKIESQVTALQQEAQRLASSGDVSGAQSKAKEAESIVKQAQNTDPKQFVKMKTETKKEQVKIGAIVDDALYSDGIMISLPTAERLTSKDMMMVTQMYVQAKPGANIERLGKNLEKAVKPFYTISVLTRDEFKSSMSSMINSMLAIIYALLALSIIIAIFGIVNTLALNVSERTKEIGLLRAIGTSNGQVRGMLAIEAVILSVFGTLVGIVVGVAAGVVIRIAYESQGMTTLTIPWDQLVLFLIVAILVGLIASISPARRALKHPVLNAVASE
>NC_011835.1|WP_004218710.1|939871_940123_+|hypothetical-protein
MRLPERIPVGARVVVRITDGVDEYTGRHQYRDYVGHVRAWDGRTLQLTRDAAANGSRPAQDVDISATDIAILKPVPERPAARR
>NC_011835.1|WP_004218709.1|940138_941233_-|prephenate-dehydrogenase/arogenate-dehydrogenase-family-protein
MHEETIKQWDRDNAGEPQIAPEGIECPKHVAIVGLGLIGGSLARRLRESGCHVSAWNHRDHPYANARAAGIDCKDTLEELVAEEPDVLMLCNPLVAMPQVLQTIKPIINPQKTTLSDVGSVKGPVRTQVSEVGLLDCYVGAHPMAGNEHSGWVAADPTLFDDALWAVTFGLHTQYRRVVQIAGMITRGVRNTMIVIDDVTHDREASLISHMPHVLSTALINEMTSDANNAIASALSAGSWRDMTRVALTDPDRTRAMVVENAHNVEELLHRMIDWLSEFANALHEEDETEIRHFFAEGQPYRDYKAQINAGKVSDSTETIFQSLRIDPEHWREQLLKSAQRGEYIVRFTSGHRLIAEQHPSIRS
>NC_011835.1|WP_004218708.1|941241_942357_-|chorismate-mutase
MTRQSTRIHYLGPQGSFTHQAAIESAAEASRRLHMDVADFEFVACDTVPQILHAVELGQGWGTIAWENNVEGFVVPNLDLMMDAADAAGFLRVGVNVRFDAFVTERTYRHACEQYASEIAVDDAQIPARDNANAYGAASTPPTIDELAIRDCTAVCAHSHGLAQCRRFAREHGLKPVPAASNAAACRDLQDFQIALGPSICANIYGLHRVAANVGDFDGARTEFLTIAPRSQVVERLRIPRSDPKTEFESVIAFIPLVTGPGVLANLLDVLRDAQLNMVSLISRPVKGRDGTYSFLATLDAAPWDERFVNALVEICEHGDWVRTLAVYPRDERNYPTVSEWMLPAGGVRFEGEPHMANWRESADVRKELLW

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Crispr_ID: NC_011835_6

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_011835_6

1181706-1181817

Orphan

Consensus_repeat	Method
AAACAGGCGAGGGCATATCTGAGGGGCAGAGGCGCT	CRISPRCasFinder

1 spacers

The CRISPR arrays of NC_011835_6

>merge|NC_011835|6|1181706-1181817|CRISPRCasFinder
AAACAGGCGAGGGCATATCTGAGGGGCAGAGGCGCTTCGTCAAGGTGTCTGCGCGCTACGCGCGTAGCACGCTCCTAAACAGGCGAGGGCATATCTGAGGGGCAGCGGCGCT

>NC_011835|6|5|1181706-1181817|CRISPRCasFinder
AAACAGGCGAGGGCATATCTGAGGGGCAGAGGCGCT	TCGTCAAGGTGTCTGCGCGCTACGCGCGTAGCACGCTCCT
AAACAGGCGAGGGCATATCTGAGGGGCAGCGGCGCT

Protein	Signature genes	Signature genes Name	Protein_function
NC_011835.1\|WP_004217578.1\|1180446_1181703_+\|ABC-transporter-permease	unknown	unknown	gnl\|CDD\|378925
NC_011835.1\|WP_004217577.1\|1179131_1180412_+\|ABC-transporter-permease	unknown	unknown	gnl\|CDD\|378925
NC_011835.1\|WP_041777821.1\|1168797_1170132_-\|ABC-transporter-substrate-binding-protein	unknown	unknown	gnl\|CDD\|379175
NC_011835.1\|WP_004269154.1\|1187540_1190243_+\|DNA-translocase-FtsK	unknown	unknown	gnl\|CDD\|224588
NC_011835.1\|WP_004217587.1\|1191194_1191821_+\|CinA-family-protein	unknown	unknown	gnl\|CDD\|234789
NC_011835.1\|WP_004269158.1\|1183985_1184750_-\|GTP-pyrophosphokinase-family-protein	unknown	unknown	gnl\|CDD\|225232
NC_011835.1\|WP_004217575.1\|1176795_1177962_-\|signal-transduction-histidine-kinase	unknown	unknown	gnl\|CDD\|226951
NC_011835.1\|WP_004217584.1\|1186335_1187370_+\|tRNA-(adenosine(37)-N6)-dimethylallyltransferase-MiaA	unknown	unknown	gnl\|CDD\|234626
NC_011835.1\|WP_004217590.1\|1192488_1192740_+\|DUF3046-domain-containing-protein	unknown	unknown	gnl\|CDD\|378612
NC_011835.1\|WP_004218354.1\|1172727_1173831_+\|tryptophan--tRNA-ligase	unknown	unknown	gnl\|CDD\|183400
NC_011835.1\|WP_004217576.1\|1178108_1179098_+\|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|224054
NC_011835.1\|WP_004218356.1\|1172219_1172567_-\|DUF3073-domain-containing-protein	unknown	unknown	gnl\|CDD\|378620
NC_011835.1\|WP_004217579.1\|1181827_1182853_-\|dihydrodipicolinate-reductase	unknown	unknown	gnl\|CDD\|226326
NC_011835.1\|WP_004217589.1\|1191843_1192359_+\|helix-turn-helix-transcriptional-regulator	unknown	unknown	gnl\|CDD\|238045
NC_011835.1\|WP_004217574.1\|1176142_1176799_-\|response-regulator-transcription-factor	unknown	unknown	gnl\|CDD\|225107
NC_011835.1\|WP_014483180.1\|1174021_1175317_+\|ISL3-like-element-IS2001-family-transposase	unknown	unknown	gnl\|CDD\|376574
NC_011835.1\|WP_004269161.1\|1175345_1176161_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|376177
NC_011835.1\|WP_004217580.1\|1183114_1183900_+\|Bax-inhibitor-1/YccA-family-protein	unknown	unknown	gnl\|CDD\|198414
NC_011835.1\|WP_012619879.1\|1190358_1191012_+\|CDP-diacylglycerol--glycerol-3-phosphate-3-phosphatidyltransferase	unknown	unknown	gnl\|CDD\|273139
NC_011835.1\|WP_004269157.1\|1184864_1186355_+\|tRNA-(N6-isopentenyl-adenosine(37)-C2)-methylthiotransferase-MiaB	unknown	unknown	gnl\|CDD\|237674

Protein	Function_ID	Function_description	E-value
NC_011835.1\|WP_004217578.1\|1180446_1181703_+\|ABC-transporter-permease	gnl\|CDD\|378925	pfam12698, ABC2_membrane_3, ABC-2 family transporter protein. This family is related to the ABC-2 membrane transporter family pfam01061.	8.82582e-14
NC_011835.1\|WP_004217577.1\|1179131_1180412_+\|ABC-transporter-permease	gnl\|CDD\|378925	pfam12698, ABC2_membrane_3, ABC-2 family transporter protein. This family is related to the ABC-2 membrane transporter family pfam01061.	7.7497e-26
NC_011835.1\|WP_041777821.1\|1168797_1170132_-\|ABC-transporter-substrate-binding-protein	gnl\|CDD\|379175	pfam13416, SBP_bac_8, Bacterial extracellular solute-binding protein. This family includes bacterial extracellular solute-binding proteins.	4.42793e-35
NC_011835.1\|WP_004269154.1\|1187540_1190243_+\|DNA-translocase-FtsK	gnl\|CDD\|224588	COG1674, FtsK, DNA segregation ATPase FtsK/SpoIIIE and related proteins [Cell division and chromosome partitioning].	4.05786e-145
NC_011835.1\|WP_004217587.1\|1191194_1191821_+\|CinA-family-protein	gnl\|CDD\|234789	PRK00549, PRK00549, competence damage-inducible protein A; Provisional.	3.71156e-43
NC_011835.1\|WP_004269158.1\|1183985_1184750_-\|GTP-pyrophosphokinase-family-protein	gnl\|CDD\|225232	COG2357, COG2357, PpGpp synthetase catalytic domain [General function prediction only].	1.72281e-66
NC_011835.1\|WP_004217575.1\|1176795_1177962_-\|signal-transduction-histidine-kinase	gnl\|CDD\|226951	COG4585, COG4585, Signal transduction histidine kinase [Signal transduction mechanisms].	7.19472e-25
NC_011835.1\|WP_004217584.1\|1186335_1187370_+\|tRNA-(adenosine(37)-N6)-dimethylallyltransferase-MiaA	gnl\|CDD\|234626	PRK00091, miaA, tRNA delta(2)-isopentenylpyrophosphate transferase; Reviewed.	2.94457e-131
NC_011835.1\|WP_004217590.1\|1192488_1192740_+\|DUF3046-domain-containing-protein	gnl\|CDD\|378612	pfam11248, DUF3046, Protein of unknown function (DUF3046). This family of proteins with unknown function appears to be restricted to Actinobacteria.	1.06683e-27
NC_011835.1\|WP_004218354.1\|1172727_1173831_+\|tryptophan--tRNA-ligase	gnl\|CDD\|183400	PRK12282, PRK12282, tryptophanyl-tRNA synthetase II; Reviewed.	6.21754e-114
NC_011835.1\|WP_004217576.1\|1178108_1179098_+\|ABC-transporter-ATP-binding-protein	gnl\|CDD\|224054	COG1131, CcmA, ABC-type multidrug transport system, ATPase component [Defense mechanisms].	1.15504e-91
NC_011835.1\|WP_004218356.1\|1172219_1172567_-\|DUF3073-domain-containing-protein	gnl\|CDD\|378620	pfam11273, DUF3073, Protein of unknown function (DUF3073). This family of proteins with unknown function appears to be restricted to Actinobacteria.	8.53389e-24
NC_011835.1\|WP_004217579.1\|1181827_1182853_-\|dihydrodipicolinate-reductase	gnl\|CDD\|226326	COG3804, COG3804, Uncharacterized conserved protein related to dihydrodipicolinate reductase [Function unknown].	1.23291e-31
NC_011835.1\|WP_004217589.1\|1191843_1192359_+\|helix-turn-helix-transcriptional-regulator	gnl\|CDD\|238045	cd00093, HTH_XRE, Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators.	2.66652e-07
NC_011835.1\|WP_004217574.1\|1176142_1176799_-\|response-regulator-transcription-factor	gnl\|CDD\|225107	COG2197, CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain [Signal transduction mechanisms / Transcription].	7.3283e-47
NC_011835.1\|WP_014483180.1\|1174021_1175317_+\|ISL3-like-element-IS2001-family-transposase	gnl\|CDD\|376574	pfam01610, DDE_Tnp_ISL3, Transposase. Transposase proteins are necessary for efficient DNA transposition. Contains transposases for IS204, IS1001, IS1096 and IS1165.	5.16573e-58
NC_011835.1\|WP_004269161.1\|1175345_1176161_+\|hypothetical-protein	gnl\|CDD\|376177	pfam18755, RAMA, Restriction Enzyme Adenine Methylase Associated. An alpha+beta fold domain associated with restriction enzymes across prokaryotes and fused to JAB deubiquitinases, and chromatin proteins in a wide range of eukaryotes. The domain is predicted to function as a modified-DNA reader domain.	1.90584e-11
NC_011835.1\|WP_004217580.1\|1183114_1183900_+\|Bax-inhibitor-1/YccA-family-protein	gnl\|CDD\|198414	cd10432, BI-1-like_bacterial, Bacterial BAX inhibitor (BI)-1/YccA-like proteins. This family is comprised of bacterial relatives of the mammalian members of the BAX inhibitor (BI)-1 like family of small transmembrane proteins, which have been shown to have an antiapoptotic effect either by stimulating the antiapoptotic function of Bcl-2, a well-characterized oncogene, or by inhibiting the proapoptotic effect of Bax, another member of the Bcl-2 family. In plants, BI-1 like proteins play a role in pathogen resistance. A characterized prokaryotic member, Escherichia coli YccA, has been shown to interact with ATP-dependent protease FtsH, which degrades abnormal membrane proteins as part of a quality control mechanism to keep the integrity of biological membranes.	9.25694e-49
NC_011835.1\|WP_012619879.1\|1190358_1191012_+\|CDP-diacylglycerol--glycerol-3-phosphate-3-phosphatidyltransferase	gnl\|CDD\|273139	TIGR00560, pgsA, CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase. Alternate names: phosphatidylglycerophosphate synthase; glycerophosphate phosphatidyltransferase; PGP synthase. A number of related enzymes are quite similar in both sequence and catalytic activity, including Saccharamyces cerevisiae YDL142c, now known to be a cardiolipin synthase. There may be problems with incorrect transitive annotation of near homologs as authentic CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase. [Fatty acid and phospholipid metabolism, Biosynthesis].	8.8374e-27
NC_011835.1\|WP_004269157.1\|1184864_1186355_+\|tRNA-(N6-isopentenyl-adenosine(37)-C2)-methylthiotransferase-MiaB	gnl\|CDD\|237674	PRK14326, PRK14326, (dimethylallyl)adenosine tRNA methylthiotransferase; Provisional.	0

>NC_011835.1|WP_004217578.1|1180446_1181703_+|ABC-transporter-permease
MILVYIVYLSLMMFGLSWSIIQNLSNTDNSTTYETLRPEVAVVDRNGGVGSGFSDSLRKFLSKDCDLVDVGTTSQDLQTAAASNYADLIVIIPEHYVDDLAAAFTSDSAVPELQMVTSFTGAYGSLAKLQVEDFLNLTRMTALADAASSGSSVSVASLNAAAGSVIADLTGNADAYPQIAIAEDPAGTDDREANGRYAFQTMMDMGAYPMVAAMFTITAMTMGSFSGARVRRRMYASPQRTGSMLFQQFACCGLFGVLVSLFYLALALALPVAAGLPITGVDPRGFLLCALTMVAYSLTAAASGFMVSMIAVNSAAINAIANVYGLVIMFTSGMAFPVDLMPKVMIVIGKCTPGWWFCRSISAAMNSEGTVSVSNWFPGIALVLLFGVAFIALGLALSQMRRLRPNLAAPASTQLAEV
>NC_011835.1|WP_004217577.1|1179131_1180412_+|ABC-transporter-permease
MWSTFLNTMRVNLREKSSVFWLFCFPIILSTMFMGMFGNIGEVYEIHTMRFAVVADANFCRATNARQMLHAMQRNPLRNEGCGNAMEGAAPDTASGQVGSELRNLLELQAVSNVKEAKGLINADHGVRGYINATEDGLLNLTISRASVASVNDDTGNSGFSASLNILHGAVGMFNRRAITVTELLNTDSGVFRDATFTKEMGDTPTFTKVVSPTHFKPTESVRFYYALLAMTALMSMTFATTTVCATQANLSALGMRRSLAPLSKFNQLMGGFLASWLCASVSMVVATLYVHFVCKVDFGGRWPVLVLALLLASLTANALGTLIGSLPKLTSGVKIGITTALSCVLSIFSGLYGTGAMNLSDWTQRNAPGFAIVNPTQQITNLFYDLLHYDSYAPSLRTSGILLAMTVLALTLSTIFLRRQRYEHL
>NC_011835.1|WP_004217576.1|1178108_1179098_+|ABC-transporter-ATP-binding-protein
MNTAENNVQRDAAPAIEVRELVKRYADKLALDYLNMNVRTGEIYGLLGPNGSGKTTAINCILGLLTYDSGQIRAFGGKMGPTAYDLKRRIGVVPQDVAVFNELTVQENIEYFCSLYVADKMRRARLVDEAIEFVGLEDYRRFRPRKLSGGLPRRLNIACGIVHQPEPIFFDEPTVAVDPQSRNSILEGIKRLNERGATVVYTSHYMEEVEQICDRIQIIDHGRQIAIGTADELKRMIEAGERITVEAPALSANEALCQRAVSMLGDLEAVHEVTFENDELVVVCSQGEHNLIDVLQVLRSLDIPMGHVSSRAPTLNDVFLALTGTDLRD
>NC_011835.1|WP_004217575.1|1176795_1177962_-|signal-transduction-histidine-kinase
MIISVGAHALMFVVSVLFSVMLSGDTDTTFVIGLLFCVILCSLIRLAPLRCWIALAMMFCMVCLFVPQWIALMPIVGFDLGLRVQSLGRSFQMLVCVPPLVCGIVAGQHSPALHDLSAAATSPLVMALWILCALTSLAVLGGWVFALAQRRQRCFQSLADDQRERIRRSRARLADVESARSADLQHARLTERTRIAREIHDNVGHLLTRAIMLTNADQVIATSTGDTLHADQFGQLGHTLDEAMTMIRKSVHGLKDEGTDFRAMVEDAMATAKQSDVEIRLSNAIDAVPSHVAHAFTAVIRGALTNTIRHSAASEAHVHLIDLPGLWQLIVQGNGGVPERGRVASMGIGIADIEERARALDGTATCGYHNGGWRVFMSVPKTAERNMR
>NC_011835.1|WP_004217574.1|1176142_1176799_-|response-regulator-transcription-factor
MKVAIVDDDPIVCSSIGTILTTTGTAEVVWTAHDGAAAVVAYARQKPDVLLIDVQMPGTDGLEASERILVLTTFADPEYIRRAIELGTKGYLIKQDVASVIPAVQAVMAGQVVLGADVLRNLPMHDASGNVEEPKASPLPDDPRFAHLTDREHDIVELVAEELDNREIAAKLFLSEGTVRNRISGILAKTHISNRTKLAIEWLTSHDRHIHDHHIEVR
>NC_011835.1|WP_004269161.1|1175345_1176161_+|hypothetical-protein
MQRIAGFHVDGDEQRLAMLHLRGELSIDSNMKRLLLIRANEQLAGGRITRPRSLNAVPLIPVRIQSGSDFADWPAGQCDYWAERIGNYVLTQSTRKSMEGLDDFQTRRARILRSPSSRQFPLTRVIGELEKLTPQFLQLRQHQIVELIAQAWNINPGELGSLAEPQGQSDRTGTSAHRSRRTSKRVTVGEVVRAGLLTVGDRFVWNRPRKHEIWRITVTESGFRGEDGTEYATPTSAARAIGGSSASLNVWKRESDGRALSDIWKTYRTSM
>NC_011835.1|WP_014483180.1|1174021_1175317_+|ISL3-like-element-IS2001-family-transposase
MFDPQRFLGLDEMGLRVLSWRRLGRPDGPGLRQIRCEPDSHDARWCPSCGAYARVRSSWLRTLAHVPYGDDAVHLLVRVRRYECVPCSRSWSDDPEAVGAGRGVLSVPAVMWALRRVCLDSMTVSACARLLHVAWAVVDRAVRERGMLLLEQADRFSSVRAIGVDEHVWRHGAFGDRYVTVIVDLTPRCDGRPARLLDMVPGRSAQVLREWMQARGGEFTRRVGVVAMDAFAGWKQAVESVVPHAVEVIDPFHVVQLAAARVTRVRCRLQRDATGRRGVKGDRLYDCRRALLTSDEYLGARGRARLMALFAIQANRDLMLAHDAYQRVIHAYRCDDRRRGERMMRELIDDLTGPGRYKGCRELASLGRVLKRRMRDILALFRHPRSSNGPTEAINGRLETLRGNAMGFANTTSYIQRCLIHSSQLKDILTH
>NC_011835.1|WP_004218354.1|1172727_1173831_+|tryptophan--tRNA-ligase
MTDDMNAQLTAAGNEMSASFLAAKKRSDETLAKLKANPGKFTMLTGDRPTGRLHLGHFFGSIRERVAMQNLGVNTNIIIADYQVITDRDTTEHIDDNVLNLVLDYMAAGIDPEKTMIFTHSAVPAENQLMLPFLSLVTEAELHRNPTVKSEMESSGHALTGLLLTYPVHQACDILFCKANVVPIGKDNLPHVEITRTIARRFNERYAKKNPVFPEPAAILSEAPEIPGLDGRKMSKSYGNSIMLGATAEETAKLIKKSPTDSERTITFDPVNRPQVSALLTTAGLVTGRDPSEIAAEIGNAGAGALKKYVIDSVNEFLAPHRERRAELAKDMDSVRDILHDGNARANAIANQTLDEVREAMGMRYDR
>NC_011835.1|WP_004218356.1|1172219_1172567_-|DUF3073-domain-containing-protein
MGRGRQKAKQQKIARKLKYMTTDTDYDELAKELGAHEPGTGSFDPFADVENDEFEAQDVDETVDDLDEYAKWAAEAAAKATTGEMPETHAQPKPKPHKPIPMPVPETFKHTDQQE
>NC_011835.1|WP_041777821.1|1168797_1170132_-|ABC-transporter-substrate-binding-protein
MNRTVKATVGLVAIAAMSLTGLAACGGSSADDGKGKVYFLNFKPEAADQWVALAKKYTDKTGVQVKVQTAASGTYEQTLKSELAKSDAPTIFQVNGPVGYQNWKGYTADLKDTGIYNELNNKDIALKDGDKVVGIPYVMETYGIIYNKDLLKKYTELPGAKIKDVKEIDSFDKLKEVADDMQAKKDQLGIKGAFTSAGFDSSSDWRFKTHLANIPLSYEFKEDGVTTQPETIKGTYLPNFKNIFDLYLKDSTTAPSQLSSKTGDDANSEFALGEAAFYQNGTWAWTDLQKAGMKPDQVGMLPIYIGAKGEENQGLATASSENCLCVNAKASEADQKASKDFLNWVVTSDEGIKALSEDMGFTTPFKTFDKVKSDNPLVEEAVEDSNSGKEQVAWNFTMMPSEEWQNQLGQAMLAYAQGTGSWDDVRKAFVDNWKTEYDNAHANQ
>NC_011835.1|WP_004217579.1|1181827_1182853_-|dihydrodipicolinate-reductase
MEPIRAIQFGCGKMAKYTVRYMHDKGMQIVGAIDVNPDVVGMDVGEFAGIGPLNVTISDDADAVLDSCDADIAVVTLFSFMDDIEPMCEACLSRGISVITTCEEAIYPWTTNPAVTNRLDRIAKENGATMVGSGMQDIFWINMVAQVAGGCNSMTKISGATSYNVEDYGLALAKAHGVGLTAEQFEEQLAHPDEVVPSYVWNSNESLVQRLGLTIKSQTQRAVPYFSDVDVYSETMGETIPAGVCIGMSAVVTTETMQGLTIETSCIGKVYGPDDGDMCDWRIEGEPDTEFHVVKPATVEHTCATMVNRIPNVLNAPAGYVTVDQLPEINHLSYPAAMYVA
>NC_011835.1|WP_004217580.1|1183114_1183900_+|Bax-inhibitor-1/YccA-family-protein
MTYGQQPMNGSPYGQQPYGQQPMNYANTINVQASQSYERAEHVSVTRAYGEMCLGLLVTAAMAIFTQMSGFYMRFLQATGGMGMWILAIVEIGLAIYLGMRVMKMSTTAARVCFYVYAALMGVTLSTIFLAYDLGTIGIAFLVSAGFYFALTMFGLTTKGNMLKAGPILMIALVVLIIAEVIMMFVAPSNTMLKVVTAIGILLFAGLTIYDAQFTKKAFAVYASQGPEAIKKISILCALNLYLDFINLFLYILQALGLSRD
>NC_011835.1|WP_004269158.1|1183985_1184750_-|GTP-pyrophosphokinase-family-protein
MNTAEIRARLTAAGHSLGLDGTEEGERGVDLITDFINQMQIYEGAMYEISTKLEILDSEFQVQFSHNPIHHLERRLKSTESILGKLDRRGLPYTVEAIRDNLFDVAGIRVICNYRDDVYSVANYLSAQSDIQVLRVKDYIRNPKQNGYRSLHVIYAVPVFLSSGAHYTPVEVQFRTIAMDYWASLEHALRYKTDLPDDKHAEHSQTLLDCARALQNVETQMQTIHRDINGAPQGGEAPTANEDSPIRNATLKGQ
>NC_011835.1|WP_004269157.1|1184864_1186355_+|tRNA-(N6-isopentenyl-adenosine(37)-C2)-methylthiotransferase-MiaB
MNEDMMTPEERRTNISQAQHTTQVEPGAPQYGGASGRGRGLYYVHTLGCQMNVHDSERIAGVMEENGYRPASEEQFLAHDVDVVIMNTCAVRENATERMYGTIGKWKRFKYRNPHAQIAIGGCMAQLDRERIAKRTPWVDAVFGTKNIEDLPALLDQARAAQHTQVKVNEDLTLFPSQLPAHRASAHSAWVAISMGCNNTCTFCIVPTTRGKERDRRPGDVLAEIRETVTNGAKEITLLGQNVNSYGYGIGDRYAFSKLLRACGEIEGLERVRFTSPHPAAFTDDVIAAMAETPNVMHQLHFPLQSGSDRILRAMRRSYRSERFLGILAKIREAMPDAQISTDIIVGFPGETEEDFQQTLRVVEEARFSSAFTFIYSPRPGTPAAAMEQVPYDVALDRLERLLAVQERITEEILEKFVGRDVEVMITGVTGKKDAETHRYTGREKTGVLVHVGVPEGHDAPQIGDFVTATVTHAGRHNLIADPDLAKGQTYAIRRS
>NC_011835.1|WP_004217584.1|1186335_1187370_+|tRNA-(adenosine(37)-N6)-dimethylallyltransferase-MiaA
MPSAGVERHDGARVISIVGPTASGKTGLGIAIARRLADRGERAEIVNADAYQMYRGMDIGTAKASDEERAAVRHHLLDVIEPSETMSVARFQQMARETIADLKSRGIRPILVGGSGLYARAAIDDISFPGTDPQIREHLEERERTEGATALFRELAVKDPQAAEHMDPRNPRRIIRALEVIEVTGKPYSATLPRYRYVIPSVQLGLDLDRADLDKRIDVRTRQMFDGGFVDEVARLRSHLGPTAARALGYQQVIDHLDGLVDLDDTMADIAQKTKRLARKQMGWFGRDPRIHWLSALNPALVDNAMAVIDHADAGDYDAIDMHAQEYVQHHLGDIRRPSGAGPV
>NC_011835.1|WP_004269154.1|1187540_1190243_+|DNA-translocase-FtsK
MPRAFGSAVRKVSVGEYDPAYRRDGLCFVMIILAVFFCGSEWFRVDGALGRGLHSFASAIFGVMSVVVPVLLIVLAIRLMRNSGKQSHNTQVIAGGVMLLWSICSIIDVIMAADTKEFSWQNIQQAGGLVGFVVGSPLAWGLSQTFAIIVFVVAAVFSVLLMTRTHVTEIPQKLSRFSRRGSADSADAQQSDPEVGQFLNEVRVGDDTLAFADGVPAHDGTDVPEPDSKVGFLARLFHRRGKGPGTDTKLDRYAGDEAFLNAASRHGDANETDLHEGPRRVSSGGAFNDDATRSIDSGTWNAQPSGTIPLPSGSMPAATATGTDPWAHLDAEGETMVVSTQTGEILDRSPASSPMPPTGSRIPPAMPSPATPEDHEGMPDIPQQPDAPYHLPDLNLLVKGKPHAAHTQANDTVIHALNETFRQFKVDAKVVGFLRGPSVTQYEVEVAPGVKVEKVTNLDKNIAYAVASSDVRILSPIPGKSAIGIEIPNADREIVHLGDVLRSDKAMNDPNPMLTGVGKDVEGHFVTADLTKMPHLLVAGATGSGKSSFINSMLTSIIMRATPDQVRMIMVDPKRVELSAYAGIPHLITPIITDPKKAAQALEWVVKEMDARYSDLEFFGFRDVKDFNKAVRAGKVHAPAGSNRKVAPYPSLLVVVDEMADLMMVAKNDVESSIQRITQLARAAGVHLVLATQRPSVDVITGLIKANIPSRLAFATSSATDSRVILDTTGAETLIGQGDALFLPMGSAKPIRVQGAWVNESEIRKAVEFVRTQRKPHYREDIEQMAKEADQKKVDPTEDIGGDMDELLQAAELVVSSQFGSTSMLQRKLRVGFAKAGRLMDLLESRGVVGPSEGSKAREVLVQPQDLPQVLAFIKGESGSLTGARAPAEPTSGASGTAEY
>NC_011835.1|WP_012619879.1|1190358_1191012_+|CDP-diacylglycerol--glycerol-3-phosphate-3-phosphatidyltransferase
METEKSTKQSMWSQWSSPPNLVTLARIVLVVVFLGLYIGGGAWGARNIGMRWGAAIVFIIAASTDKIDGWMARKYNQVTELGKLLDPIADKLLTLGALVVAACFNEFGNMWIGWIVTGLYVVREIGITIMRFFVIDHGGKVIAASQAGKYKTFTLCLGLGLLLIPVWSFTHAVSQPAWLTVYFIVAYALIYFSLILCLYSGYEYLRGVFAKPAVTRK
>NC_011835.1|WP_004217587.1|1191194_1191821_+|CinA-family-protein
MAELFEVAELAGVTDVADVQRYCDEQARHILAHCDVRGLKIACAESLTAGLLADSFVRIPGASSVFLGSAVTYDIHAKAMVLGVDAELLRTHGAVDPEVARQMARGAAHLFYQEQYAHGVVGLSTTGVAGPGPDEGKPAGTVYIGFDVPCFSHSVIQERDFALRLALRGSRELVRHLTVACVLGKMREFTGSSQEKIPIMETRETHEG
>NC_011835.1|WP_004217589.1|1191843_1192359_+|helix-turn-helix-transcriptional-regulator
MEQMTMVNEQVEVKSVETPEQVRSGSARMRELTPAQRRAVMFAQQQVLRARAAKKAKDEHQAALARMWQEEDAETARPRAMVHRRETVGEVKEVSLRKAIGHVLRDLRTRDHKTLREVSEKAGVSLGYLSEVERGQKEASSELLASISESLGLSTSQMLRMVADYLDSVEA
>NC_011835.1|WP_004217590.1|1192488_1192740_+|DUF3046-domain-containing-protein
MLGAMREREFWQLLEEVFGRSYGRALAHDQGLTKLHGMTVVEALAAGEEPRVVWNVLCGQMDVPDAKRWGRDHNAPPLPVDFH

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Crispr_ID: NC_011835_7

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_011835_7

1906861-1906951

Orphan

Consensus_repeat	Method
TTGGCGTCCATGTCACGCGCGGAATCGAT	CRISPRCasFinder

1 spacers

The CRISPR arrays of NC_011835_7

>merge|NC_011835|7|1906861-1906951|CRISPRCasFinder
TTGGCGTCCATGTCACGCGCGGAATCGATCGTCCGAGAGTGGATTCGCGGATTGTCTTGATCTTGGCGCCCATGTCACGCGCGGAATCGAT

>NC_011835|7|6|1906861-1906951|CRISPRCasFinder
TTGGCGTCCATGTCACGCGCGGAATCGAT	CGTCCGAGAGTGGATTCGCGGATTGTCTTGATC
TTGGCGCCCATGTCACGCGCGGAATCGAT

Protein	Signature genes	Signature genes Name	Protein_function
NC_011835.1\|WP_004218981.1\|1902615_1903611_+\|23S-rRNA-(guanosine(2251)-2'-O)-methyltransferase-RlmB	unknown	unknown	gnl\|CDD\|223640
NC_011835.1\|WP_004218989.1\|1913956_1914850_+\|16S-rRNA-(adenine(1518)-N(6)/adenine(1519)-N(6))--dimethyltransferase-RsmA	unknown	unknown	gnl\|CDD\|234708
NC_011835.1\|WP_004218977.1\|1898519_1899101_-\|dCTP-deaminase	unknown	unknown	gnl\|CDD\|234753
NC_011835.1\|WP_004218987.1\|1910562_1911600_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|235012
NC_011835.1\|WP_004218988.1\|1912267_1913815_+\|G5-domain-containing-protein	unknown	unknown	gnl\|CDD\|226111
NC_011835.1\|WP_004218984.1\|1905415_1906549_-\|sn-glycerol-3-phosphate-ABC-transporter-ATP-binding-protein-UgpC	unknown	unknown	gnl\|CDD\|236947
NC_011835.1\|WP_004218990.1\|1914846_1915803_+\|4-diphosphocytidyl-2C-methyl-D-erythritol-kinase	unknown	unknown	gnl\|CDD\|224858
NC_011835.1\|WP_004218991.1\|1915874_1916501_+\|LytR-C-terminal-domain-containing-protein	unknown	unknown	gnl\|CDD\|379163
NC_011835.1\|WP_004218971.1\|1893127_1893637_-\|nucleoside-deaminase	unknown	unknown	gnl\|CDD\|223663
NC_011835.1\|WP_004218969.1\|1890789_1893012_-\|alpha-galactosidase	unknown	unknown	gnl\|CDD\|307952
NC_011835.1\|WP_004218985.1\|1906972_1907995_+\|potassium-channel-family-protein	unknown	unknown	gnl\|CDD\|369572
NC_011835.1\|WP_004218975.1\|1896910_1898470_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|380155
NC_011835.1\|WP_004268865.1\|1916630_1918049_-\|CCA-tRNA-nucleotidyltransferase	unknown	unknown	gnl\|CDD\|131739
NC_011835.1\|WP_015940210.1\|1925751_1926714_+\|thioredoxin-disulfide-reductase	unknown	unknown	gnl\|CDD\|273540
NC_011835.1\|WP_004218996.1\|1919241_1921491_+\|hypothetical-protein	unknown	unknown	unknown
NC_011835.1\|WP_004218979.1\|1899310_1902301_-\|cation-translocating-P-type-ATPase	unknown	unknown	gnl\|CDD\|223550
NC_011835.1\|WP_004218995.1\|1918234_1919239_+\|NUDIX-hydrolase	unknown	unknown	gnl\|CDD\|239645
NC_011835.1\|WP_004218982.1\|1903759_1905208_-\|DUF4032-domain-containing-protein	unknown	unknown	gnl\|CDD\|379077
NC_011835.1\|WP_004218974.1\|1895929_1896868_-\|esterase	unknown	unknown	gnl\|CDD\|223477
NC_011835.1\|WP_004218973.1\|1893786_1895859_+\|Na+/H+-antiporter	unknown	unknown	gnl\|CDD\|223104

Protein	Function_ID	Function_description	E-value
NC_011835.1\|WP_004218981.1\|1902615_1903611_+\|23S-rRNA-(guanosine(2251)-2'-O)-methyltransferase-RlmB	gnl\|CDD\|223640	COG0566, SpoU, rRNA methylases [Translation, ribosomal structure and biogenesis].	2.52914e-72
NC_011835.1\|WP_004218989.1\|1913956_1914850_+\|16S-rRNA-(adenine(1518)-N(6)/adenine(1519)-N(6))--dimethyltransferase-RsmA	gnl\|CDD\|234708	PRK00274, ksgA, 16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase RsmA.	7.3034e-125
NC_011835.1\|WP_004218977.1\|1898519_1899101_-\|dCTP-deaminase	gnl\|CDD\|234753	PRK00416, dcd, deoxycytidine triphosphate deaminase; Reviewed.	4.37887e-92
NC_011835.1\|WP_004218987.1\|1910562_1911600_+\|hypothetical-protein	gnl\|CDD\|235012	PRK02201, PRK02201, putative inner membrane protein translocase component YidC; Provisional.	0.000728081
NC_011835.1\|WP_004218988.1\|1912267_1913815_+\|G5-domain-containing-protein	gnl\|CDD\|226111	COG3583, COG3583, Uncharacterized protein conserved in bacteria [Function unknown].	2.68164e-36
NC_011835.1\|WP_004218984.1\|1905415_1906549_-\|sn-glycerol-3-phosphate-ABC-transporter-ATP-binding-protein-UgpC	gnl\|CDD\|236947	PRK11650, ugpC, sn-glycerol-3-phosphate ABC transporter ATP-binding protein UgpC.	2.85165e-175
NC_011835.1\|WP_004218990.1\|1914846_1915803_+\|4-diphosphocytidyl-2C-methyl-D-erythritol-kinase	gnl\|CDD\|224858	COG1947, IspE, 4-diphosphocytidyl-2C-methyl-D-erythritol 2-phosphate synthase [Lipid metabolism].	1.14612e-58
NC_011835.1\|WP_004218991.1\|1915874_1916501_+\|LytR-C-terminal-domain-containing-protein	gnl\|CDD\|379163	pfam13399, LytR_C, LytR cell envelope-related transcriptional attenuator. This family appears at the C-terminus of members of the LytR_cpsA_psr, pfam03816, family.	3.21486e-16
NC_011835.1\|WP_004218971.1\|1893127_1893637_-\|nucleoside-deaminase	gnl\|CDD\|223663	COG0590, CumB, Cytosine/adenosine deaminases [Nucleotide transport and metabolism / Translation, ribosomal structure and biogenesis].	2.26822e-59
NC_011835.1\|WP_004218969.1\|1890789_1893012_-\|alpha-galactosidase	gnl\|CDD\|307952	pfam02065, Melibiase, Melibiase. Glycoside hydrolase families GH27, GH31 and GH36 form the glycoside hydrolase clan GH-D. Glycoside hydrolase family 36 can be split into 11 families, GH36A to GH36K. This family includes enzymes from GH36A-B and GH36D-K and from GH27.	5.11586e-158
NC_011835.1\|WP_004218985.1\|1906972_1907995_+\|potassium-channel-family-protein	gnl\|CDD\|369572	pfam07885, Ion_trans_2, Ion channel. This family includes the two membrane helix type ion channels found in bacteria.	1.60974e-15
NC_011835.1\|WP_004218975.1\|1896910_1898470_-\|hypothetical-protein	gnl\|CDD\|380155	NF012221, MARTX_Nterm, MARTX multifunctional-autoprocessing repeats-in-toxin holotoxin RtxA. This model describes the N-terminal 1900 amino acids of MARTX family multifunctional-autoprocessing repeats-in-toxin holotoxins, which contain both repeat regions that facilitate their entry into eukaryotic target cells, and multiple effector domains.	0.000288677
NC_011835.1\|WP_004268865.1\|1916630_1918049_-\|CCA-tRNA-nucleotidyltransferase	gnl\|CDD\|131739	TIGR02692, putative_tRNA_nucleotidyltransferase, tRNA adenylyltransferase. The enzyme tRNA adenylyltransferase, also called tRNA-nucleotidyltransferase and CCA-adding enzyme, can add or repair the required CCA triplet at the 3'-end of tRNA molecules. Genes encoding tRNA include the CCA tail in some but not all bacteria, and this enzyme may be required for viability. Members of this family represent a distinct clade within the larger family pfam01743 (tRNA nucleotidyltransferase/poly(A) polymerase family protein). The example from Streptomyces coelicolor was shown to act as a CCA-adding enzyme and not as a poly(A) polymerase. [Protein synthesis, tRNA and rRNA base modification].	0
NC_011835.1\|WP_015940210.1\|1925751_1926714_+\|thioredoxin-disulfide-reductase	gnl\|CDD\|273540	TIGR01292, Thioredoxin_reductase, thioredoxin-disulfide reductase. This model describes thioredoxin-disulfide reductase, a member of the pyridine nucleotide-disulphide oxidoreductases (pfam00070). [Energy metabolism, Electron transport].	8.4585e-151
NC_011835.1\|WP_004218979.1\|1899310_1902301_-\|cation-translocating-P-type-ATPase	gnl\|CDD\|223550	COG0474, MgtA, Cation transport ATPase [Inorganic ion transport and metabolism].	0
NC_011835.1\|WP_004218995.1\|1918234_1919239_+\|NUDIX-hydrolase	gnl\|CDD\|239645	cd03673, Ap6A_hydrolase, Diadenosine hexaphosphate (Ap6A) hydrolase is a member of the Nudix hydrolase superfamily. Ap6A hydrolase specifically hydrolyzes diadenosine polyphosphates, but not ATP or diadenosine triphosphate, and it generates ATP as the product. Ap6A, the most preferred substrate, hydrolyzes to produce two ATP molecules, which is a novel hydrolysis mode for Ap6A. These results indicate that Ap6A hydrolase is a diadenosine polyphosphate hydrolase. It requires the presence of a divalent cation, such as Mn2+, Mg2+, Zn2+, and Co2+, for activity. Members of the Nudix superfamily are recognized by a highly conserved 23-residue nudix motif (GX5EX7REUXEEXGU, where U = I, L or V), which forms a structural motif that functions as a metal binding and catalytic site.	3.99945e-50
NC_011835.1\|WP_004218982.1\|1903759_1905208_-\|DUF4032-domain-containing-protein	gnl\|CDD\|379077	pfam13224, DUF4032, Domain of unknown function (DUF4032). This presumed domain is functionally uncharacterized. This domain family is found in bacteria, and is approximately 170 amino acids in length. The family is found in association with pfam06293.	6.16001e-95
NC_011835.1\|WP_004218974.1\|1895929_1896868_-\|esterase	gnl\|CDD\|223477	COG0400, COG0400, Predicted esterase [General function prediction only].	9.25712e-25
NC_011835.1\|WP_004218973.1\|1893786_1895859_+\|Na+/H+-antiporter	gnl\|CDD\|223104	COG0025, NhaP, NhaP-type Na+/H+ and K+/H+ antiporters [Inorganic ion transport and metabolism].	2.14183e-78

>NC_011835.1|WP_004218984.1|1905415_1906549_-|sn-glycerol-3-phosphate-ABC-transporter-ATP-binding-protein-UgpC
MAEVIFDHVTRIYPGNDKPSVDDLNLDIKDGEFLVLVGPSGCGKSTTLRMLAGLEEVNKGRILIGGKDVTTMQPKDRDIAMVFQNYALYPHMTVADNMGFALKIAGTPKDEIRKRVEKAAEILDLTEFLDRKPKALSGGQRQRVAMGRAIVREPKVFLMDEPLSNLDAKLRVQTRTQIAALQRQLGVTTLYVTHDQTEALTMGDRIAVIKLGILQQVGAPTELYDRPANVFVAGFIGSPSMNINTHPVVNGKAQIGADTMELPKEALDKLTPEDKNEIIVGFRPEDASLAAPDEANAFSLKVVNVEDLGSDGYIYGNIITDDSVAQKTTDTLMSDQNQLTTIRVNPRVLPKVGDVVKIKVNPAKMHLFSPSTELRLN
>NC_011835.1|WP_004218982.1|1903759_1905208_-|DUF4032-domain-containing-protein
MGITDNPQLDPRALKATSVKAEDPATPGPGPSTLKITAASSDPKMFTLPWEKPLATWPPELLVNLPRGISRHIVRFVHVGDEVYAMKEITRTVAEREYELLRQLQKLNLPTVQPIAVVTGRHDDNGEPLEAILVTKHLRFSMPYRALFARTLRPDTAERLIDALAVLMVRLHLAGFYWGDVSLSNVLFLKDADAFSAFLVDAETGDLQIELTAGQREYDIDLARTNIIGELMDLSSGELLPPDVDEISIGNRLVDRYHSLWSALTDTDNFSPNEMWKIEKRVNRLNELGFDVDELEMKTAEDGKRVLVRPRVVDAGYANRRLLRLTGLDVQENQARRLLNDLDAYRASSWREGEDLEIVATDWMREVFEPTVRMIPREYRSQIEPAQFFHEVLDHRWYMAEKAGHDVPMAEAVQSYIKNVLPQYQLDTKTVNELNADADAGVVDDEYTYDDASNNGAHTAPAAGHDDGYNPEDDPDAAVWAH
>NC_011835.1|WP_004218981.1|1902615_1903611_+|23S-rRNA-(guanosine(2251)-2'-O)-methyltransferase-RlmB
MATKKGPTKGSGGKHRNSLRGKGPTPKAEDRVYHKAYKAKKQAEKRQRSDPRLAARRRAAHFTSNSDDLVIGRNSVLEALRVGVPASVLYVANRIEHDDRTREIVRLAGQHGLNLLEADRLEMDRIARSGNHQGVILKADPFQYSSLHELVERAERKARAMEMADSKASRLSARPLFIALDGITDPQNLGAVIRSAAAFGVNGVILPERRSASVNAAAWKVSAGAAAHMPIARVVNLTKAIEALKERGYYSIGLDGGGSKLVGETGFETDPLVVVLGSEGKGLSRLTREACDAIASIPITSAVESLNASVAAGIALYATVNARRKAGEAAN
>NC_011835.1|WP_004218979.1|1899310_1902301_-|cation-translocating-P-type-ATPase
MDDRIIDPSALNREPHVEPADAEESKEVKAQEALLHDVDPSLASADEVAEALNVDTHTGLSSEEAKRRLEKFGANELASAPPVPKWKKFLQQFQDPLVYLLLAATAISLVAWIIEKVNAAPGAEGGEALPFDAIVIVLILIVNAVLGYVQEAKADEAVNALSEMTAPTSNVLRNGRVERIATTDIVPGDVLVLGEGDTVPADGRLFAAASLRIAEASLTGESVPVGKKPETLEKAKALGDRSNMVFNGTSVTQGTGRAIVTGTGMNTQVGKIADLLQSTEDDTTPLQKEMNHVSKILGIAVCIIAVVVLVALAVLEGFHSVHDVIDSLLLAVSLAVAAVPEGLATILTVVLALGVQRMAAHHAIVKKLHSVETLGSASVICSDKTGTLTRNEMTVERVVVPSGEVELTGTGYAPEGDMVSLNGDAVPENIAQEVYATLGAGTLANDGELREGPKPGTWEIVGDPTEVSLVVAARKTHADKRFHHFTRVAEIPFTSERKRMSVITKNDTDSGKLTVFAKGAPDVLLSYCDRIFVNGAVRKLTEGDRQDILKKVEELSREAYRTLGEAYRPLETASLSEVPGIRTNAAGDVSDISEQADVIEHQLVWTGMVGIIDPPRVEVRDAVAEAHRAGVRTVMITGDHPLTAARIASDLGIIEQGGKALTGDELDSMDEKQLDKATSEVSVYARVAPEHKLKIVESLQRQGNIAAMTGDGVNDAPAVKAADIGVAMGITGTEVTKQSAKMILADDNFSTIVAAVREGRGIFDNIRKFLRYLLSSNVGEVFTVFLGVVLAGFLGIKNPDSVGVTVPLLATQLLWINLLTDAAPALAMGVDPTTEDVMNRKPRKLTDRVIDGAMWGDIVYIGLIMAIVTLIGMDMHLSGGVFTDRSVDALGHDAQMVEARTMGFTILVFAQLFNAIASRSHLQSAFKGLFSNKWLWGAIALSIVLQLLVIYVPWLNTAFGTTPLPPMAWLECIGLAAIVLVASEIRKIFLRMRATH
>NC_011835.1|WP_004218977.1|1898519_1899101_-|dCTP-deaminase
MLLSDRDIRAAHAEGHISLDPWTDEMVQPASIDVRLDRFFRLFNNHAYTYVDPAENQGELTEQFEVGPDEPWILHPGEFALGSTWEYVKIDETLAARLEGKSSLGRLGILTHSTAGFIDPGFEGHITLELSNVSTLPVKLWPGMKIGQMCFFQLSSPSEHPYGSETTGSHYQGQRGPTPSRSYQNFYRAQITD
>NC_011835.1|WP_004218975.1|1896910_1898470_-|hypothetical-protein
MTDSGNPSDLQFPVSPEPRDFDVTHVVDKDALEFPSMDDDPSHAAAHESQLQSAGSANTAAIPAPPVNGHPHDHARRTARSGAHDATPTPDETPADSAALTLAASQPSAGRHAANTVNGASAGDAAPTQLFTSPHDDVLAGVSVNPPLPAEEPTRVVSSEWEQIVDSQTSVMPPAAPAAMPPAIPPTDADGNADGSGDEPDEEAPHHSANGGGKSHTKLIAGIVVGVLVIALIAGGIAWWSSSRRNNAQRNAYTLCQNTRDSYDDAHTALAAALKDANALTSTPTDQVADAKTLDTLKSAVADAEKLDQQSVAECAVDANTAAIEKTTDSLRNTANEITKAKSALDAATKAVNDSKNMQSQSAARDELTKAIDDAQKILDASANAVTDEQVRTDLENRIADARKLADGQNLNAEDVTAMVKTLTDAGTAVQQSQTEYANQQAATAQQAAEEAQRQAEAQAQAAQQAQQNAAQAQQQNAQTTTPDTSDAGTAGDGTTGAGATGTDGETTGNGGTPANGAQ
>NC_011835.1|WP_004218974.1|1895929_1896868_-|esterase
MSTADDTPNPDDPFEPSDDPEHLDDLSRELDDLVDFANLEREMTEAANTTPSGPYAGQSAGERKRMEPPVGRVASVVPGHFGDRLTVTEALASRGGGNAQPNRPLFVCLHGWGSNEDDLAGIMRYVAPYSDFVSLRAPLVLQEASPRGFAMQQGAYSWFHDAVPVGDDLDYDAYAAACAIDDWVTTNVGENRDVVPIGFSQGGTLAVELLRVHPQRYRAAISLSGFVAPGNVPATTPYDDILADLNIPVFYGYGELDTVLPKYMIYETIAWLEEHTWLTARGYRGLDHAVSMEEFSDLRQWLLDQDIASGII
>NC_011835.1|WP_004218973.1|1893786_1895859_+|Na+/H+-antiporter
MSVLILILCILGAVLLSSFLSRFLPRISTPLVQIVLGLIASQMPFFPDVQLDPELFLVLFIAPLLYLEAHEINKSQLLKSLKLSLSLAIGLAIFTMVVVGFSLHTLWPMFPLAAALALGAALGPTDAVAVSSLSHEATLTQRQIGVLKGESLFNDASGIVGFQFAIAAAVTGQFRVGEAAWEFLITFFGGAVFGCIVGVLANWVFESSRQLGWETTTTRILMELFLPFLLYLGAEAVHVSGILSVVAAGLVIRFDRTGIGPNVARTNIVASSVWSVLSFSLNGAVFILLGMLLPGAMRASWDNPMVSNYTLLAVILCVSTLIVGLRFLWVSGMLRLARAQDSHKRRRMTPERWRSAAVMTFGGAKGTITLSLMFTIPYTIADGEWFPMRDELIFIAGGVIIVTLLLSNFLLPVIAPNKAKDVPRETTEASIEVLRRTVEELAELTTDENRSAVMVVINSYTQRIGRLKNQLGTIDPSARIELQIDALNWEKEYVKRKLAEFRLDPTLSEREREVNVEACERLLDQIMDTLRHTNTKHDSSHVVWQVKGRAHLAQRRLVLLSRRAANTIRRSTPLVNENEIYASLRNLELGAFDHVIDRLYEEMSSNTYGTEYVSSLLMDYRRAEAALKSRPNMANSASLVTQIEDVKRESFGIELSVIQNMVEAGDITRAQARQLRKNVYVMSVAADSNF
>NC_011835.1|WP_004218971.1|1893127_1893637_-|nucleoside-deaminase
MRAGGRWHAYKGRGGIAMTQYAEAMGEALAQARMARSAGDVPVGAVVLDAHGEVIGRGRNLRERDADPLAHAEIVAMREAAAVRGNWNLADCTLVVTLEPCPMCAGACLQTRIGRIVFGGWDAKLGACGSVWDIPRDPHVGHEPEVYGGVCERECTALLAEFFHSRRHA
>NC_011835.1|WP_004218969.1|1890789_1893012_-|alpha-galactosidase
MTRISEFNATTHAGEALHVVSMENHDADSAFALAFVADELPRVVHWGRPLTQPRTLVSAVDALRPQRVSGALDETTWPSVLPTQAEAWTGEPRFVVRRDGVELFCRFVVTDIAVGDAGVAVTASDAEQGVEIIWTCEMRDSGLVRQRADVRNLGAGSLEIGKVELGFPVPADMTELLTTTGHHLRERSPQRQPLTIGRFQKASMVGRPDFDASLLLNAGRPGFGFTHGDVYAVHVAWSGNSLMAAERLPYTTGVIGGAEVLAGGEITLHDAADSYTTPWLYGSFGEGLNEVAARFHADLRATHARWRAEHGIADKPRPVILNTWEAVYFEHDYDTLVRLADKAAASGVERFVVDDGWFGDRRGDTAGLGDWRISQDVWPDGEHSLKALADYVHAKGMEFGLWFEPEMVNPDSAMYREHSDWVLMPTAHRLPMQGRNQQVVDLTNPQAYAYVYGCMDSLVGELGIDYIKWDHNKYVTEAVSPRTGSCAVHGQTLAVYRMFHDLKTSHPGLEIESCSSGGGRVDMGILELADRIWASDCVDPVERADIQRYTSLLVPPEMIGEHVGASPAHSTHRATSQEMRMAMAFFGHLGIEWNLLKEPQHDLDLLGEWVHAYKEHRVDFEHGVAVHDDAADPTVRVDGVISADGARAVYRFTQLTTSQTYPAAPIALPGLDAQATYRVRPLALNMASGEPFGEIGNGQSELGWWNANGVEMTGEALASYGLRPPSIHPANAVLFSVTRV
>NC_011835.1|WP_004218985.1|1906972_1907995_+|potassium-channel-family-protein
MTARKSARRPGLTLHTWQHYTNAPMFVLSAFFLFAYSWQILAGTHTRLCNLVINLVWVLYSIDYAISLYLAPNRWSWFKSNLILLITMILPMFQPLRLLRFVPMLHMFNRSAGTASRGRISLYAVAVVAMLIYVGALAEYSVEHKAPGATITSFPLSIWWAFVTVTTVGYGDVYPVTTLGRFIAIILMITGIAVIGIVSAMISSWVIDQVNVRPHPVIPAPAVGEDGGASPSANASTHDAGGCPDEDYTTGDEDIIDAPDPLNGSSLGPSLNPAQSRIVQAELLRLTDSVNRLHNEIEQLRRAEHRHMQASGQTARKLRWHANRNGHMPPHDSPEGDKPA
>NC_011835.1|WP_004218987.1|1910562_1911600_+|hypothetical-protein
MAANSKQPKRESRAQRRQEEQARVQAKRERLQKERRTQTIIGIVVTVVLIALIAIAGIAVYRNTHPSAARQQEAANEQSAAQATLKDSKVKPAKASELGGLLMSKNGYNKPVEGVPTVGIYMDFMCPGCGNLNRNLDQDLVKMMDAGQINIDLHIMSFMDRYSWINGDSNNVDDYSSRTANAAIYVAEHDDDPNHLLNFITNLYAKDFQPEEGSGYKQVTDDQIKVRMDGTGISKDVQGKAMQRGYDKWLDAVNTYTPTRSELFNRSGQLKGSMSTPTMTINGYYWDMNSSEVTSHKTLAEAFLEAIGLAQNKVGDAEVRPSIGATGKPLIGYADDNAGAATNSQ
>NC_011835.1|WP_004218988.1|1912267_1913815_+|G5-domain-containing-protein
MARRWTPQRMMRLRTIRIASSMVTIVALLLGFFVCTRKTVALEVNGKTTTVTTFATTIPGFLREQHVKLKTHDLVRSSTPGQLTDNSTVTVQSAYQTTISIDGQQMPFWTVADSAEQLIAFFEQNEVAANRITVDIKNVYNQLTGGLVINADGPVTVIADGKTFIAPNGKLPAASILDSKGITLGKNDRVSVSKDGSQTILRVERVTTKEITETEDVPFSTQTIVDDSLEPGATEVRQEGRNGQNQLRYRVTYVDGKEDSRELLDTTPLSTPIDRIIAIGPEPVKETPQKEDNSGASNDEGQSADQSAGNSAGTNDKQSATENNTGDAAEPSAESSPTPSAQPSQQPGAKPSEQPTSKPTQSAQPTQKPSEQPTQQPSAQPTQQPKPTPTPTQKPTQQPEQPTPSNCRLCKPSPSAAQAYAAGAAAQYGWTGKNWEDLVKLWNRESSWLWYAENKSSGAYGIPQSLPGSKMAQFGENWKEDAAVQIDWGLNYIATHPKYGSPSKAWAHSEKYGWY
>NC_011835.1|WP_004218989.1|1913956_1914850_+|16S-rRNA-(adenine(1518)-N(6)/adenine(1519)-N(6))--dimethyltransferase-RsmA
MGTAQADGGNLLGAADIRRIAAEEGITPTKKFGQNFVIDPGTVRKIVREAGVDAGDQVMEVGPGLGSLTLAILETGADLTAVEIDPPLAQRLPQTIAEFMPNATNRFRVVNMDALKVTPSQLPQLADAATFTLVANLPYNVATPILLTLLERFGNLDSFLVMVQKEVAERLSAQPGSKVYGTPSVKLAWYGTAKSVGNIGRNVFWPAPNVDSALVRFERHAADDPRNPNNRSVGRDLVFRLIDASFAQRRKTLHAALRKIVPSGAFERAGIDPTRRGETLDIDEFVALATACKELEA
>NC_011835.1|WP_004218990.1|1914846_1915803_+|4-diphosphocytidyl-2C-methyl-D-erythritol-kinase
MSAPNGARFQTPTLRADYASVHVDCPAKTNLTLHVGERREEWGGRHALETIYCGVGIYDTVTVTAKEPGTGFSLDLAGTHLGDLAASTSDMRRNHAVLAMFAMAQASGHEPDVSISIEKRIPVAAGLGGGSADAAGTLLALNALWNLNWPVARLREIAAALGADMPFCVTGGLALGTGFGERIKDLTASDPRIEHAVGDLFADAPSGDGVHMLVGAYLSQLSTPEVYSTFDVLGAGEGDLNELQHAAVSLHPRSGVAIREAQQAGATSAFVSGSGPTVIAVVPDDRVREATRAAWQASGAVDRIIDAQAPAAPLMRAE
>NC_011835.1|WP_004218991.1|1915874_1916501_+|LytR-C-terminal-domain-containing-protein
MAENNDAREERREYVHRRQTIVFAVVGAVLVVALFISSLFLFHVGGLGEVKTTAEGADHGVVAPCVSPAEDGSKPKYLDSKSVTTRVLNGTKFSGFANAVGRALQNREFVVQSIDNYDNAKVERTTIVFGKNAIPQAYTLAANFPDAQLQMDDRQDKLVDVILGATFQNLTKTDELPKTGSEIPNIEGCKPANDMKDLPKAPEHTSVG
>NC_011835.1|WP_004268865.1|1916630_1918049_-|CCA-tRNA-nucleotidyltransferase
MNFEVWPEAIELGQMFADEGFELALVGGPVRDLLLHRRSHDLDFCSNARPEQFEPILRRFGHDGFWDMGRKFGTLGAMRRRPDGTEVKVEVTTYRSDVYDPDSRKPEVSYGDSLEGDLSRRDFTVNAMALTVPDLEFVDPFGGANDLNKRVLRTPVDPYQSFDDDPLRMMRAVRFVAQLGFSIEPETAEAITRMTDRIEIVSAERVRDELTKLLLSDRPRAGIEALVDSGLADVVLPEIPALRLEIDEHHRHKDVFDHTMIVVDRAVALETGPDGPVPAPDLVLRLAALMHDIGKPKTRRFEPGGKVSFHHHDAVGAKMTRKRLKALRFDHHVVEQVSDLVDLHLRFHGYVDEPWTDAAVRRYVKDAGPLYARLNRLTRADATTQNRRKALMFEHAMDEMEERVAKLKEQEDIDAIRPDLNGDEIMAELGIAPGPLVGKAYRHMLEYRLDNGPVDHDTAVAELHNWYASQAE
>NC_011835.1|WP_004218995.1|1918234_1919239_+|NUDIX-hydrolase
MITPADVARMHANAAVNHALSPDDPDFDPLVPDELMYTSQTTTVHLNTVLDEARAVKAKLGAERIESASTQAAHMPTPADMPSHPTSHEAAQEQSGPSEDTVPNQARGTRRIPTPAQVAQAAHAARMMQALHATQPLYSSQPVPAQSTAVPAHPMRNAARRDPGKPTPAMMPQRRSTDRRSSFASLDAQELPVVREYSAGGLVFDAHGRVAIIARHSRSGHLEWCLPKGHIEKGETPQQTAVREIHEETGIIGEVVDSIATIDYWFTGTSQRVHKLVHHFALRQTGGELTVEGDPDHEAEDAIWVDFADLDDVLSYPNERKIAWLYARKLNRQA
>NC_011835.1|WP_004218996.1|1919241_1921491_+|hypothetical-protein
MNPHRTDLRHTARQRCKGTALLTVLFTLILALCTGFAVRPAHAEEPDATTNTDQAAKPGVSITVNSMTPVITPSSGYKLNLTVTNNTDADVDHGSIDALTNFTYNFISRTDLQEWAEGRGQIPLPDLLVTLHVPRIAAHKSVTVNSSLPASEEILKQFNSWGPRPLALDYRSDDGAQTSTLHSFVTRSQDGLQGERTPQLHMTMLMPLTAGDWSLDETTLKALRADRSAKTHASAIATLDGKSAEALRTKDQLTQRFPHVQALADPQVLATLQAPHMQALMQPADFDITRYSYADNANGYENAGVPLSSWAASSSVQTLRTVLNDGAAERPVYAMQGVGAWNTEALDTARMQGYDTVIATHDFDDQDDTAAHTGVYRVPTAHGDVTVMATHPMLSQLAAGQATSQEAQAETNTAGRLQRFIAQSAFYQMEQPYQNRCLLVSFGPDSSAANIAAFMGALQEASWLDLTDLETLRASEPYMSGDDAATVADTTTVDPAAYDTTTLDTTLTTLAHTRRDLQHFNTSVLLADGSMPGGPAAQTGDANNTKPGDGDANDADDASDNATSDTSGDALGALQWSNRWLQAHDELALLSLNANTARSSALTAATQAMVDYLRQGIGLTTPTNVNVVSESASLPVTVTNSLPYPISLRISSRTDSMEIVTSRFVDVNVPPGSEAQATLEIRVSTAGTTVANQELVNHEGVPLSGIHTTTITSSLQISDKSGIVFIIIAVLLGIVGLWRQFHRKKDPDE
>NC_011835.1|WP_015940210.1|1925751_1926714_+|thioredoxin-disulfide-reductase
MNSTATVHNVIIVGSGPAGYTAAIYLARAGLKPVVVAGALTPGGQLINTTEVENYPGFPDGVMGSDLMESMQRQAERFGAEIVFDDVESADLQGELKSVHLSGGQDLQTRTVIVATGSNYRHLNVPGELEYSGKGVSYCATCDGFFFRGKPIVVVGGGDSAMEEANFLARFGSSVTLIHRRDEFRASQIMVERTRENPKINLLMNTVVERINGDGKGVTSLDLRNTATNETSKIEANGVFVAIGHVPQTGFLGGQLDLDDHGYIRIDETSTGATRTSVPGVFAAGDCADAIYQQAIVAAGSGCRAALDVQSYLEDIPEGI

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Click the colored protein region to show detailed information

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity
NC_011835_6	6.1\|1181742\|40\|NC_011835\|CRISPRCasFinder	1181742-1181781	40	NC_011835.1	1306809-1306848	1	0.975

1. spacer 6.1|1181742|40|NC_011835|CRISPRCasFinder matches to position: 1306809-1306848, mismatch: 1, identity: 0.975

tcgtcaaggtgtctgcgcgctacgcgcgtagcacgctcct	CRISPR spacer
tcgtcaaggtgtctgcgcgcttcgcgcgtagcacgctcct	Protospacer
********************* ******************

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NC_011835_4	4.1\|906949\|26\|NC_011835\|CRISPRCasFinder	906949-906974	26	NC_014811	Mycolicibacterium gilvum Spyr1 plasmid pMSPYR101, complete sequence	16807-16832	4	0.846
NC_011835_1	1.7\|183989\|28\|NC_011835\|CRISPRCasFinder	183989-184016	28	NZ_CP042628	Escherichia coli strain NCYU-25-82 plasmid pNCYU-25-82-1_MCR3, complete sequence	11972-11999	5	0.821
NC_011835_1	1.7\|183989\|28\|NC_011835\|CRISPRCasFinder	183989-184016	28	NZ_CP053739	Escherichia coli strain CP8-3_Sichuan plasmid pCP8-3-IncR, complete sequence	4124-4151	5	0.821
NC_011835_1	1.7\|183989\|28\|NC_011835\|CRISPRCasFinder	183989-184016	28	NZ_CP053721	Escherichia coli strain CP131_Sichuan plasmid pCP131-IncHI1, complete sequence	93964-93991	5	0.821
NC_011835_1	1.7\|183989\|28\|NC_011835\|CRISPRCasFinder	183989-184016	28	CP042642	Escherichia coli strain NCYU-24-74 plasmid pNCYU-24-74-4_MCR3, complete sequence	11974-12001	5	0.821
NC_011835_1	1.7\|183989\|28\|NC_011835\|CRISPRCasFinder	183989-184016	28	LC549805	Escherichia coli VNCEc117 plasmid pVNCEc117 DNA, complete sequence	24862-24889	5	0.821
NC_011835_1	1.7\|183989\|28\|NC_011835\|CRISPRCasFinder	183989-184016	28	NZ_CP042618	Escherichia coli strain NCYU-26-73 plasmid pNCYU-26-73-3_MCR3, complete sequence	120679-120706	5	0.821
NC_011835_1	1.7\|183989\|28\|NC_011835\|CRISPRCasFinder	183989-184016	28	NZ_CP041114	Escherichia coli strain ECCTRSRTH03 plasmid unnamed4, complete sequence	26292-26319	5	0.821
NC_011835_1	1.7\|183989\|28\|NC_011835\|CRISPRCasFinder	183989-184016	28	NZ_CP033094	Escherichia coli strain CP53 plasmid pCP53-mcr, complete sequence	76080-76107	5	0.821
NC_011835_1	1.7\|183989\|28\|NC_011835\|CRISPRCasFinder	183989-184016	28	NZ_CP035200	Klebsiella pneumoniae strain LH375 plasmid pLH375-3, complete sequence	38316-38343	5	0.821
NC_011835_1	1.7\|183989\|28\|NC_011835\|CRISPRCasFinder	183989-184016	28	NZ_CP035208	Klebsiella quasipneumoniae strain TH114 plasmid pTH114-3, complete sequence	57753-57780	5	0.821
NC_011835_1	1.7\|183989\|28\|NC_011835\|CRISPRCasFinder	183989-184016	28	NZ_CP035213	Klebsiella pneumoniae strain TH164 plasmid pTH164-3, complete sequence	62999-63026	5	0.821
NC_011835_1	1.7\|183989\|28\|NC_011835\|CRISPRCasFinder	183989-184016	28	NZ_CP035195	Klebsiella pneumoniae strain LH102-A plasmid pLH102-A, complete sequence	580-607	5	0.821
NC_011835_1	1.7\|183989\|28\|NC_011835\|CRISPRCasFinder	183989-184016	28	MH114596	Salmonella enterica strain 13-1681 plasmid p131681, complete sequence	94181-94208	5	0.821
NC_011835_1	1.7\|183989\|28\|NC_011835\|CRISPRCasFinder	183989-184016	28	NZ_CP050727	Salmonella enterica subsp. enterica serovar Typhimurium strain ST113 plasmid pST-1, complete sequence	96797-96824	5	0.821
NC_011835_1	1.7\|183989\|28\|NC_011835\|CRISPRCasFinder	183989-184016	28	NZ_MK656937	Escherichia coli strain T3 plasmid pT3, complete sequence	66543-66570	5	0.821
NC_011835_1	1.7\|183989\|28\|NC_011835\|CRISPRCasFinder	183989-184016	28	NZ_MH341574	Klebsiella pneumoniae strain MYKLB95 plasmid MYKLB95-1, complete sequence	63574-63601	5	0.821
NC_011835_1	1.7\|183989\|28\|NC_011835\|CRISPRCasFinder	183989-184016	28	NZ_MF678351	Escherichia coli strain WCHEC025943 plasmid pMCR3_WCHEC1943, complete sequence	11573-11600	5	0.821
NC_011835_1	1.7\|183989\|28\|NC_011835\|CRISPRCasFinder	183989-184016	28	NZ_CP035205	Klebsiella pneumoniae strain LH94 plasmid pLH94-3, complete sequence	56399-56426	5	0.821
NC_011835_1	1.7\|183989\|28\|NC_011835\|CRISPRCasFinder	183989-184016	28	NZ_KX377410	Klebsiella pneumoniae strain WCHKP1511 plasmid pMCR_1511, complete sequence	54987-55014	5	0.821
NC_011835_1	1.7\|183989\|28\|NC_011835\|CRISPRCasFinder	183989-184016	28	MG780294	Escherichia coli plasmid pHN8, complete sequence	16608-16635	5	0.821
NC_011835_1	1.7\|183989\|28\|NC_011835\|CRISPRCasFinder	183989-184016	28	NZ_CP042602	Escherichia coli strain NCYU-29-69 plasmid pNCYU-29-69-3_MCR3, complete sequence	23677-23704	5	0.821
NC_011835_1	1.7\|183989\|28\|NC_011835\|CRISPRCasFinder	183989-184016	28	NZ_CP053734	Escherichia coli strain CP55_Sichuan plasmid pCP55-IncFII, complete sequence	7728-7755	5	0.821
NC_011835_1	1.7\|183989\|28\|NC_011835\|CRISPRCasFinder	183989-184016	28	NZ_CP053729	Escherichia coli strain CP61_Sichuan plasmid pCP61-IncFIB, complete sequence	62482-62509	5	0.821
NC_011835_1	1.7\|183989\|28\|NC_011835\|CRISPRCasFinder	183989-184016	28	NZ_CP053725	Escherichia coli strain CP66-6_Sichuan plasmid pCP66-6-IncFII, complete sequence	28939-28966	5	0.821
NC_011835_1	1.7\|183989\|28\|NC_011835\|CRISPRCasFinder	183989-184016	28	LC549806	Escherichia coli VNCEc57 plasmid pVNCEc57 DNA, complete sequence	5619-5646	5	0.821
NC_011835_1	1.7\|183989\|28\|NC_011835\|CRISPRCasFinder	183989-184016	28	NZ_CP039562	Salmonella enterica subsp. enterica serovar 1,4,[5],12:i:- strain PNCS014847 plasmid p08-5333.1, complete sequence	168070-168097	5	0.821
NC_011835_1	1.7\|183989\|28\|NC_011835\|CRISPRCasFinder	183989-184016	28	NZ_CP041095	Klebsiella pneumoniae subsp. pneumoniae strain KPCTRSRTH01 plasmid unnamed3, complete sequence	65966-65993	5	0.821
NC_011835_1	1.7\|183989\|28\|NC_011835\|CRISPRCasFinder	183989-184016	28	NZ_CP041104	Klebsiella pneumoniae subsp. pneumoniae strain KPCTRSRTH07 plasmid unnamed5, complete sequence	19874-19901	5	0.821
NC_011835_1	1.7\|183989\|28\|NC_011835\|CRISPRCasFinder	183989-184016	28	NZ_CP042608	Escherichia coli strain NCYU-29-19 plasmid pNCYU-29-19-2_MCR3, complete sequence	4476-4503	5	0.821
NC_011835_1	1.7\|183989\|28\|NC_011835\|CRISPRCasFinder	183989-184016	28	AP018353	Escherichia coli plasmid pVE769 DNA, complete genome, strain: E769	8379-8406	5	0.821
NC_011835_1	1.7\|183989\|28\|NC_011835\|CRISPRCasFinder	183989-184016	28	AP018354	Escherichia coli plasmid pVE155 DNA, complete genome, strain: E155	9181-9208	5	0.821
NC_011835_1	1.7\|183989\|28\|NC_011835\|CRISPRCasFinder	183989-184016	28	NZ_CP050732	Salmonella enterica subsp. enterica serovar Typhimurium strain ST101 plasmid pST101-1, complete sequence	81157-81184	5	0.821
NC_011835_1	1.7\|183989\|28\|NC_011835\|CRISPRCasFinder	183989-184016	28	NZ_CP045953	Salmonella enterica subsp. enterica serovar Typhimurium strain AUSMDU00008979 plasmid pAUSMDU00008979_01, complete sequence	84530-84557	5	0.821
NC_011835_1	1.7\|183989\|28\|NC_011835\|CRISPRCasFinder	183989-184016	28	NZ_MK770642	Klebsiella pneumoniae strain T38 plasmid pT38_MCR3, complete sequence	104267-104294	5	0.821
NC_011835_1	1.7\|183989\|28\|NC_011835\|CRISPRCasFinder	183989-184016	28	NZ_AP018939	Escherichia coli strain JSWP006 plasmid pJSWP006_1, complete sequence	78720-78747	5	0.821
NC_011835_1	1.7\|183989\|28\|NC_011835\|CRISPRCasFinder	183989-184016	28	NZ_MH043623	Escherichia coli strain GDZJ002 plasmid pGDZJ002-1, complete sequence	49606-49633	5	0.821
NC_011835_1	1.7\|183989\|28\|NC_011835\|CRISPRCasFinder	183989-184016	28	NZ_MH043626	Escherichia coli strain GDZJ004 plasmid pGDZJ004, complete sequence	49219-49246	5	0.821
NC_011835_1	1.7\|183989\|28\|NC_011835\|CRISPRCasFinder	183989-184016	28	NZ_MG552133	Escherichia coli strain ECSC102 plasmid pECSC102, complete sequence	48730-48757	5	0.821
NC_011835_1	1.7\|183989\|28\|NC_011835\|CRISPRCasFinder	183989-184016	28	NZ_MF489760	Escherichia coli strain WCHEC-LL123 plasmid pMCR3_WCHEC-LL123, complete sequence	50908-50935	5	0.821
NC_011835_1	1.7\|183989\|28\|NC_011835\|CRISPRCasFinder	183989-184016	28	NZ_MH077952	Escherichia coli strain EC17S-208 plasmid p17S-208, complete sequence	23294-23321	5	0.821
NC_011835_1	1.7\|183989\|28\|NC_011835\|CRISPRCasFinder	183989-184016	28	NZ_MH043625	Escherichia coli strain GDZJ003 plasmid pGDZJ003-1-MCR-3, complete sequence	49236-49263	5	0.821
NC_011835_1	1.7\|183989\|28\|NC_011835\|CRISPRCasFinder	183989-184016	28	NZ_CP027203	Escherichia coli strain WCHEC025943 plasmid pMCR3_025943, complete sequence	36962-36989	5	0.821
NC_011835_1	1.6\|183937\|29\|NC_011835\|CRISPRCasFinder	183937-183965	29	NZ_CP023068	Ensifer sojae CCBAU 05684 plasmid pSJ05684b, complete sequence	1640519-1640547	6	0.793
NC_011835_1	1.6\|183937\|29\|NC_011835\|CRISPRCasFinder	183937-183965	29	MH067974	Arthrobacter sp. strain ANT_H58 plasmid pA58H1, complete sequence	31125-31153	6	0.793
NC_011835_1	1.5\|183885\|29\|NC_011835\|CRISPRCasFinder	183885-183913	29	NZ_CP018233	Rhizobium leguminosarum strain Vaf-108 plasmid unnamed5, complete sequence	133734-133762	7	0.759
NC_011835_1	1.5\|183885\|29\|NC_011835\|CRISPRCasFinder	183885-183913	29	NZ_CP016293	Rhizobium leguminosarum strain Vaf10 plasmid unnamed5, complete sequence	235632-235660	7	0.759
NC_011835_1	1.5\|183885\|29\|NC_011835\|CRISPRCasFinder	183885-183913	29	NZ_CP022569	Rhizobium leguminosarum bv. viciae strain BIHB 1148 plasmid pSK05, complete sequence	149169-149197	7	0.759
NC_011835_3	3.13\|643660\|34\|NC_011835\|CRISPRCasFinder,CRT	643660-643693	34	NZ_CP031601	Roseovarius indicus strain DSM 26383 plasmid pRIdsm_03, complete sequence	33620-33653	7	0.794
NC_011835_3	3.32\|643661\|34\|NC_011835\|PILER-CR	643661-643694	34	NZ_CP031601	Roseovarius indicus strain DSM 26383 plasmid pRIdsm_03, complete sequence	33620-33653	7	0.794
NC_011835_1	1.6\|183937\|29\|NC_011835\|CRISPRCasFinder	183937-183965	29	NC_007950	Polaromonas sp. JS666 plasmid 2, complete sequence	275288-275316	8	0.724
NC_011835_3	3.1\|642794\|35\|NC_011835\|CRISPRCasFinder,CRT	642794-642828	35	MH001451	Mycobacterium phage Nairb, complete genome	7175-7209	8	0.771
NC_011835_3	3.1\|642794\|35\|NC_011835\|CRISPRCasFinder,CRT	642794-642828	35	MF155936	Mycobacterium phage ZenTime222, complete genome	7175-7209	8	0.771
NC_011835_3	3.1\|642794\|35\|NC_011835\|CRISPRCasFinder,CRT	642794-642828	35	MK494089	Mycobacterium phage Ibrahim, complete genome	7175-7209	8	0.771
NC_011835_3	3.1\|642794\|35\|NC_011835\|CRISPRCasFinder,CRT	642794-642828	35	NC_024135	Mycobacterium phage Bernal13, complete genome	7175-7209	8	0.771
NC_011835_3	3.1\|642794\|35\|NC_011835\|CRISPRCasFinder,CRT	642794-642828	35	MG925349	Mycobacterium phage Mendokysei, complete genome	7107-7141	8	0.771
NC_011835_3	3.1\|642794\|35\|NC_011835\|CRISPRCasFinder,CRT	642794-642828	35	KM591905	Mycobacterium phage RonRayGun, complete genome	7175-7209	8	0.771
NC_011835_3	3.1\|642794\|35\|NC_011835\|CRISPRCasFinder,CRT	642794-642828	35	MN735432	Mycobacteriophage Whitty, complete genome	7175-7209	8	0.771
NC_011835_3	3.13\|643660\|34\|NC_011835\|CRISPRCasFinder,CRT	643660-643693	34	NZ_CP045383	Labrenzia sp. THAF35 plasmid pTHAF35_c, complete sequence	15510-15543	8	0.765
NC_011835_3	3.20\|642795\|35\|NC_011835\|PILER-CR	642795-642829	35	MH001451	Mycobacterium phage Nairb, complete genome	7175-7209	8	0.771
NC_011835_3	3.20\|642795\|35\|NC_011835\|PILER-CR	642795-642829	35	MF155936	Mycobacterium phage ZenTime222, complete genome	7175-7209	8	0.771
NC_011835_3	3.20\|642795\|35\|NC_011835\|PILER-CR	642795-642829	35	MK494089	Mycobacterium phage Ibrahim, complete genome	7175-7209	8	0.771
NC_011835_3	3.20\|642795\|35\|NC_011835\|PILER-CR	642795-642829	35	NC_024135	Mycobacterium phage Bernal13, complete genome	7175-7209	8	0.771
NC_011835_3	3.20\|642795\|35\|NC_011835\|PILER-CR	642795-642829	35	MG925349	Mycobacterium phage Mendokysei, complete genome	7107-7141	8	0.771
NC_011835_3	3.20\|642795\|35\|NC_011835\|PILER-CR	642795-642829	35	KM591905	Mycobacterium phage RonRayGun, complete genome	7175-7209	8	0.771
NC_011835_3	3.20\|642795\|35\|NC_011835\|PILER-CR	642795-642829	35	MN735432	Mycobacteriophage Whitty, complete genome	7175-7209	8	0.771
NC_011835_3	3.32\|643661\|34\|NC_011835\|PILER-CR	643661-643694	34	NZ_CP045383	Labrenzia sp. THAF35 plasmid pTHAF35_c, complete sequence	15510-15543	8	0.765
NC_011835_7	7.1\|1906890\|33\|NC_011835\|CRISPRCasFinder	1906890-1906922	33	MT939492	Xanthomonas phage Xoo-sp14, complete genome	18873-18905	8	0.758

1. spacer 4.1|906949|26|NC_011835|CRISPRCasFinder matches to NC_014811 (Mycolicibacterium gilvum Spyr1 plasmid pMSPYR101, complete sequence) position: , mismatch: 4, identity: 0.846

cagacgccgtggaaaacggcgcattg	CRISPR spacer
ctgacgccgtggaagacggcgcaccg	Protospacer
* ************.********..*

2. spacer 1.7|183989|28|NC_011835|CRISPRCasFinder matches to NZ_CP042628 (Escherichia coli strain NCYU-25-82 plasmid pNCYU-25-82-1_MCR3, complete sequence) position: , mismatch: 5, identity: 0.821

taggctgtgccattttagattcctttgt	CRISPR spacer
caggctttgccattttagcttcctcttt	Protospacer
.***** *********** *****.* *

3. spacer 1.7|183989|28|NC_011835|CRISPRCasFinder matches to NZ_CP053739 (Escherichia coli strain CP8-3_Sichuan plasmid pCP8-3-IncR, complete sequence) position: , mismatch: 5, identity: 0.821

taggctgtgccattttagattcctttgt	CRISPR spacer
caggctttgccattttagcttcctcttt	Protospacer
.***** *********** *****.* *

4. spacer 1.7|183989|28|NC_011835|CRISPRCasFinder matches to NZ_CP053721 (Escherichia coli strain CP131_Sichuan plasmid pCP131-IncHI1, complete sequence) position: , mismatch: 5, identity: 0.821

taggctgtgccattttagattcctttgt	CRISPR spacer
caggctttgccattttagcttcctcttt	Protospacer
.***** *********** *****.* *

5. spacer 1.7|183989|28|NC_011835|CRISPRCasFinder matches to CP042642 (Escherichia coli strain NCYU-24-74 plasmid pNCYU-24-74-4_MCR3, complete sequence) position: , mismatch: 5, identity: 0.821

taggctgtgccattttagattcctttgt	CRISPR spacer
caggctttgccattttagcttcctcttt	Protospacer
.***** *********** *****.* *

6. spacer 1.7|183989|28|NC_011835|CRISPRCasFinder matches to LC549805 (Escherichia coli VNCEc117 plasmid pVNCEc117 DNA, complete sequence) position: , mismatch: 5, identity: 0.821

taggctgtgccattttagattcctttgt	CRISPR spacer
caggctttgccattttagcttcctcttt	Protospacer
.***** *********** *****.* *

7. spacer 1.7|183989|28|NC_011835|CRISPRCasFinder matches to NZ_CP042618 (Escherichia coli strain NCYU-26-73 plasmid pNCYU-26-73-3_MCR3, complete sequence) position: , mismatch: 5, identity: 0.821

taggctgtgccattttagattcctttgt	CRISPR spacer
caggctttgccattttagcttcctcttt	Protospacer
.***** *********** *****.* *

8. spacer 1.7|183989|28|NC_011835|CRISPRCasFinder matches to NZ_CP041114 (Escherichia coli strain ECCTRSRTH03 plasmid unnamed4, complete sequence) position: , mismatch: 5, identity: 0.821

taggctgtgccattttagattcctttgt	CRISPR spacer
caggctttgccattttagcttcctcttt	Protospacer
.***** *********** *****.* *

9. spacer 1.7|183989|28|NC_011835|CRISPRCasFinder matches to NZ_CP033094 (Escherichia coli strain CP53 plasmid pCP53-mcr, complete sequence) position: , mismatch: 5, identity: 0.821

taggctgtgccattttagattcctttgt	CRISPR spacer
caggctttgccattttagcttcctcttt	Protospacer
.***** *********** *****.* *

10. spacer 1.7|183989|28|NC_011835|CRISPRCasFinder matches to NZ_CP035200 (Klebsiella pneumoniae strain LH375 plasmid pLH375-3, complete sequence) position: , mismatch: 5, identity: 0.821

taggctgtgccattttagattcctttgt	CRISPR spacer
caggctttgccattttagcttcctcttt	Protospacer
.***** *********** *****.* *

11. spacer 1.7|183989|28|NC_011835|CRISPRCasFinder matches to NZ_CP035208 (Klebsiella quasipneumoniae strain TH114 plasmid pTH114-3, complete sequence) position: , mismatch: 5, identity: 0.821

taggctgtgccattttagattcctttgt	CRISPR spacer
caggctttgccattttagcttcctcttt	Protospacer
.***** *********** *****.* *

12. spacer 1.7|183989|28|NC_011835|CRISPRCasFinder matches to NZ_CP035213 (Klebsiella pneumoniae strain TH164 plasmid pTH164-3, complete sequence) position: , mismatch: 5, identity: 0.821

taggctgtgccattttagattcctttgt	CRISPR spacer
caggctttgccattttagcttcctcttt	Protospacer
.***** *********** *****.* *

13. spacer 1.7|183989|28|NC_011835|CRISPRCasFinder matches to NZ_CP035195 (Klebsiella pneumoniae strain LH102-A plasmid pLH102-A, complete sequence) position: , mismatch: 5, identity: 0.821

taggctgtgccattttagattcctttgt	CRISPR spacer
caggctttgccattttagcttcctcttt	Protospacer
.***** *********** *****.* *

14. spacer 1.7|183989|28|NC_011835|CRISPRCasFinder matches to MH114596 (Salmonella enterica strain 13-1681 plasmid p131681, complete sequence) position: , mismatch: 5, identity: 0.821

taggctgtgccattttagattcctttgt	CRISPR spacer
caggctttgccattttagcttcctcttt	Protospacer
.***** *********** *****.* *

15. spacer 1.7|183989|28|NC_011835|CRISPRCasFinder matches to NZ_CP050727 (Salmonella enterica subsp. enterica serovar Typhimurium strain ST113 plasmid pST-1, complete sequence) position: , mismatch: 5, identity: 0.821

taggctgtgccattttagattcctttgt	CRISPR spacer
caggctttgccattttagcttcctcttt	Protospacer
.***** *********** *****.* *

16. spacer 1.7|183989|28|NC_011835|CRISPRCasFinder matches to NZ_MK656937 (Escherichia coli strain T3 plasmid pT3, complete sequence) position: , mismatch: 5, identity: 0.821

taggctgtgccattttagattcctttgt	CRISPR spacer
caggctttgccattttagcttcctcttt	Protospacer
.***** *********** *****.* *

17. spacer 1.7|183989|28|NC_011835|CRISPRCasFinder matches to NZ_MH341574 (Klebsiella pneumoniae strain MYKLB95 plasmid MYKLB95-1, complete sequence) position: , mismatch: 5, identity: 0.821

taggctgtgccattttagattcctttgt	CRISPR spacer
caggctttgccattttagcttcctcttt	Protospacer
.***** *********** *****.* *

18. spacer 1.7|183989|28|NC_011835|CRISPRCasFinder matches to NZ_MF678351 (Escherichia coli strain WCHEC025943 plasmid pMCR3_WCHEC1943, complete sequence) position: , mismatch: 5, identity: 0.821

taggctgtgccattttagattcctttgt	CRISPR spacer
caggctttgccattttagcttcctcttt	Protospacer
.***** *********** *****.* *

19. spacer 1.7|183989|28|NC_011835|CRISPRCasFinder matches to NZ_CP035205 (Klebsiella pneumoniae strain LH94 plasmid pLH94-3, complete sequence) position: , mismatch: 5, identity: 0.821

taggctgtgccattttagattcctttgt	CRISPR spacer
caggctttgccattttagcttcctcttt	Protospacer
.***** *********** *****.* *

20. spacer 1.7|183989|28|NC_011835|CRISPRCasFinder matches to NZ_KX377410 (Klebsiella pneumoniae strain WCHKP1511 plasmid pMCR_1511, complete sequence) position: , mismatch: 5, identity: 0.821

taggctgtgccattttagattcctttgt	CRISPR spacer
caggctttgccattttagcttcctcttt	Protospacer
.***** *********** *****.* *

21. spacer 1.7|183989|28|NC_011835|CRISPRCasFinder matches to MG780294 (Escherichia coli plasmid pHN8, complete sequence) position: , mismatch: 5, identity: 0.821

taggctgtgccattttagattcctttgt	CRISPR spacer
caggctttgccattttagcttcctcttt	Protospacer
.***** *********** *****.* *

22. spacer 1.7|183989|28|NC_011835|CRISPRCasFinder matches to NZ_CP042602 (Escherichia coli strain NCYU-29-69 plasmid pNCYU-29-69-3_MCR3, complete sequence) position: , mismatch: 5, identity: 0.821

taggctgtgccattttagattcctttgt	CRISPR spacer
caggctttgccattttagcttcctcttt	Protospacer
.***** *********** *****.* *

23. spacer 1.7|183989|28|NC_011835|CRISPRCasFinder matches to NZ_CP053734 (Escherichia coli strain CP55_Sichuan plasmid pCP55-IncFII, complete sequence) position: , mismatch: 5, identity: 0.821

taggctgtgccattttagattcctttgt	CRISPR spacer
caggctttgccattttagcttcctcttt	Protospacer
.***** *********** *****.* *

24. spacer 1.7|183989|28|NC_011835|CRISPRCasFinder matches to NZ_CP053729 (Escherichia coli strain CP61_Sichuan plasmid pCP61-IncFIB, complete sequence) position: , mismatch: 5, identity: 0.821

taggctgtgccattttagattcctttgt	CRISPR spacer
caggctttgccattttagcttcctcttt	Protospacer
.***** *********** *****.* *

25. spacer 1.7|183989|28|NC_011835|CRISPRCasFinder matches to NZ_CP053725 (Escherichia coli strain CP66-6_Sichuan plasmid pCP66-6-IncFII, complete sequence) position: , mismatch: 5, identity: 0.821

taggctgtgccattttagattcctttgt	CRISPR spacer
caggctttgccattttagcttcctcttt	Protospacer
.***** *********** *****.* *

26. spacer 1.7|183989|28|NC_011835|CRISPRCasFinder matches to LC549806 (Escherichia coli VNCEc57 plasmid pVNCEc57 DNA, complete sequence) position: , mismatch: 5, identity: 0.821

taggctgtgccattttagattcctttgt	CRISPR spacer
caggctttgccattttagcttcctcttt	Protospacer
.***** *********** *****.* *

27. spacer 1.7|183989|28|NC_011835|CRISPRCasFinder matches to NZ_CP039562 (Salmonella enterica subsp. enterica serovar 1,4,[5],12:i:- strain PNCS014847 plasmid p08-5333.1, complete sequence) position: , mismatch: 5, identity: 0.821

taggctgtgccattttagattcctttgt	CRISPR spacer
caggctttgccattttagcttcctcttt	Protospacer
.***** *********** *****.* *

28. spacer 1.7|183989|28|NC_011835|CRISPRCasFinder matches to NZ_CP041095 (Klebsiella pneumoniae subsp. pneumoniae strain KPCTRSRTH01 plasmid unnamed3, complete sequence) position: , mismatch: 5, identity: 0.821

taggctgtgccattttagattcctttgt	CRISPR spacer
caggctttgccattttagcttcctcttt	Protospacer
.***** *********** *****.* *

29. spacer 1.7|183989|28|NC_011835|CRISPRCasFinder matches to NZ_CP041104 (Klebsiella pneumoniae subsp. pneumoniae strain KPCTRSRTH07 plasmid unnamed5, complete sequence) position: , mismatch: 5, identity: 0.821

taggctgtgccattttagattcctttgt	CRISPR spacer
caggctttgccattttagcttcctcttt	Protospacer
.***** *********** *****.* *

30. spacer 1.7|183989|28|NC_011835|CRISPRCasFinder matches to NZ_CP042608 (Escherichia coli strain NCYU-29-19 plasmid pNCYU-29-19-2_MCR3, complete sequence) position: , mismatch: 5, identity: 0.821

taggctgtgccattttagattcctttgt	CRISPR spacer
caggctttgccattttagcttcctcttt	Protospacer
.***** *********** *****.* *

31. spacer 1.7|183989|28|NC_011835|CRISPRCasFinder matches to AP018353 (Escherichia coli plasmid pVE769 DNA, complete genome, strain: E769) position: , mismatch: 5, identity: 0.821

taggctgtgccattttagattcctttgt	CRISPR spacer
caggctttgccattttagcttcctcttt	Protospacer
.***** *********** *****.* *

32. spacer 1.7|183989|28|NC_011835|CRISPRCasFinder matches to AP018354 (Escherichia coli plasmid pVE155 DNA, complete genome, strain: E155) position: , mismatch: 5, identity: 0.821

taggctgtgccattttagattcctttgt	CRISPR spacer
caggctttgccattttagcttcctcttt	Protospacer
.***** *********** *****.* *

33. spacer 1.7|183989|28|NC_011835|CRISPRCasFinder matches to NZ_CP050732 (Salmonella enterica subsp. enterica serovar Typhimurium strain ST101 plasmid pST101-1, complete sequence) position: , mismatch: 5, identity: 0.821

taggctgtgccattttagattcctttgt	CRISPR spacer
caggctttgccattttagcttcctcttt	Protospacer
.***** *********** *****.* *

34. spacer 1.7|183989|28|NC_011835|CRISPRCasFinder matches to NZ_CP045953 (Salmonella enterica subsp. enterica serovar Typhimurium strain AUSMDU00008979 plasmid pAUSMDU00008979_01, complete sequence) position: , mismatch: 5, identity: 0.821

taggctgtgccattttagattcctttgt	CRISPR spacer
caggctttgccattttagcttcctcttt	Protospacer
.***** *********** *****.* *

35. spacer 1.7|183989|28|NC_011835|CRISPRCasFinder matches to NZ_MK770642 (Klebsiella pneumoniae strain T38 plasmid pT38_MCR3, complete sequence) position: , mismatch: 5, identity: 0.821

taggctgtgccattttagattcctttgt	CRISPR spacer
caggctttgccattttagcttcctcttt	Protospacer
.***** *********** *****.* *

36. spacer 1.7|183989|28|NC_011835|CRISPRCasFinder matches to NZ_AP018939 (Escherichia coli strain JSWP006 plasmid pJSWP006_1, complete sequence) position: , mismatch: 5, identity: 0.821

taggctgtgccattttagattcctttgt	CRISPR spacer
caggctttgccattttagcttcctcttt	Protospacer
.***** *********** *****.* *

37. spacer 1.7|183989|28|NC_011835|CRISPRCasFinder matches to NZ_MH043623 (Escherichia coli strain GDZJ002 plasmid pGDZJ002-1, complete sequence) position: , mismatch: 5, identity: 0.821

taggctgtgccattttagattcctttgt	CRISPR spacer
caggctttgccattttagcttcctcttt	Protospacer
.***** *********** *****.* *

38. spacer 1.7|183989|28|NC_011835|CRISPRCasFinder matches to NZ_MH043626 (Escherichia coli strain GDZJ004 plasmid pGDZJ004, complete sequence) position: , mismatch: 5, identity: 0.821

taggctgtgccattttagattcctttgt	CRISPR spacer
caggctttgccattttagcttcctcttt	Protospacer
.***** *********** *****.* *

39. spacer 1.7|183989|28|NC_011835|CRISPRCasFinder matches to NZ_MG552133 (Escherichia coli strain ECSC102 plasmid pECSC102, complete sequence) position: , mismatch: 5, identity: 0.821

taggctgtgccattttagattcctttgt	CRISPR spacer
caggctttgccattttagcttcctcttt	Protospacer
.***** *********** *****.* *

40. spacer 1.7|183989|28|NC_011835|CRISPRCasFinder matches to NZ_MF489760 (Escherichia coli strain WCHEC-LL123 plasmid pMCR3_WCHEC-LL123, complete sequence) position: , mismatch: 5, identity: 0.821

taggctgtgccattttagattcctttgt	CRISPR spacer
caggctttgccattttagcttcctcttt	Protospacer
.***** *********** *****.* *

41. spacer 1.7|183989|28|NC_011835|CRISPRCasFinder matches to NZ_MH077952 (Escherichia coli strain EC17S-208 plasmid p17S-208, complete sequence) position: , mismatch: 5, identity: 0.821

taggctgtgccattttagattcctttgt	CRISPR spacer
caggctttgccattttagcttcctcttt	Protospacer
.***** *********** *****.* *

42. spacer 1.7|183989|28|NC_011835|CRISPRCasFinder matches to NZ_MH043625 (Escherichia coli strain GDZJ003 plasmid pGDZJ003-1-MCR-3, complete sequence) position: , mismatch: 5, identity: 0.821

taggctgtgccattttagattcctttgt	CRISPR spacer
caggctttgccattttagcttcctcttt	Protospacer
.***** *********** *****.* *

43. spacer 1.7|183989|28|NC_011835|CRISPRCasFinder matches to NZ_CP027203 (Escherichia coli strain WCHEC025943 plasmid pMCR3_025943, complete sequence) position: , mismatch: 5, identity: 0.821

taggctgtgccattttagattcctttgt	CRISPR spacer
caggctttgccattttagcttcctcttt	Protospacer
.***** *********** *****.* *

44. spacer 1.6|183937|29|NC_011835|CRISPRCasFinder matches to NZ_CP023068 (Ensifer sojae CCBAU 05684 plasmid pSJ05684b, complete sequence) position: , mismatch: 6, identity: 0.793

tatgctgtgccgctgcaggggtggtttgc	CRISPR spacer
cgtgctgtgccgctgcagggatggtgagg	Protospacer
..******************.****  *

45. spacer 1.6|183937|29|NC_011835|CRISPRCasFinder matches to MH067974 (Arthrobacter sp. strain ANT_H58 plasmid pA58H1, complete sequence) position: , mismatch: 6, identity: 0.793

tatgctgtgccgctgcaggggtggtttgc	CRISPR spacer
cctgctgtgctgctgcgggggtggtatcc	Protospacer
. ********.*****.******** * *

46. spacer 1.5|183885|29|NC_011835|CRISPRCasFinder matches to NZ_CP018233 (Rhizobium leguminosarum strain Vaf-108 plasmid unnamed5, complete sequence) position: , mismatch: 7, identity: 0.759

tgagatgtgcctctgatggggtggtttct	CRISPR spacer
cgagatgtgcctcttctggggtggtcagc	Protospacer
.*************  *********.  .

47. spacer 1.5|183885|29|NC_011835|CRISPRCasFinder matches to NZ_CP016293 (Rhizobium leguminosarum strain Vaf10 plasmid unnamed5, complete sequence) position: , mismatch: 7, identity: 0.759

tgagatgtgcctctgatggggtggtttct	CRISPR spacer
cgagatgtgcctcttctggggtggtcagc	Protospacer
.*************  *********.  .

48. spacer 1.5|183885|29|NC_011835|CRISPRCasFinder matches to NZ_CP022569 (Rhizobium leguminosarum bv. viciae strain BIHB 1148 plasmid pSK05, complete sequence) position: , mismatch: 7, identity: 0.759

tgagatgtgcctctgatggggtggtttct	CRISPR spacer
cgagatgtgcctcttctggggtggtcagc	Protospacer
.*************  *********.  .

49. spacer 3.13|643660|34|NC_011835|CRISPRCasFinder,CRT matches to NZ_CP031601 (Roseovarius indicus strain DSM 26383 plasmid pRIdsm_03, complete sequence) position: , mismatch: 7, identity: 0.794

tcgcaggtgaatatcggtggcggcggcttgtcgt	CRISPR spacer
tcacaggtgaatatcggtggaggcggatgatgga	Protospacer
**.***************** ***** * .* *

50. spacer 3.32|643661|34|NC_011835|PILER-CR matches to NZ_CP031601 (Roseovarius indicus strain DSM 26383 plasmid pRIdsm_03, complete sequence) position: , mismatch: 7, identity: 0.794

tcgcaggtgaatatcggtggcggcggcttgtcgt	CRISPR spacer
tcacaggtgaatatcggtggaggcggatgatgga	Protospacer
**.***************** ***** * .* *

51. spacer 1.6|183937|29|NC_011835|CRISPRCasFinder matches to NC_007950 (Polaromonas sp. JS666 plasmid 2, complete sequence) position: , mismatch: 8, identity: 0.724

tatgctgtgccgctgcaggggtggtttgc	CRISPR spacer
aaccatgtgccgctgcagggctggttgat	Protospacer
 *.  *************** ***** ..

52. spacer 3.1|642794|35|NC_011835|CRISPRCasFinder,CRT matches to MH001451 (Mycobacterium phage Nairb, complete genome) position: , mismatch: 8, identity: 0.771

gcctcctgatggatctccacgacgttgctggccct	CRISPR spacer
gattcctggtggatctccaccacgttgctgacggc	Protospacer
* .*****.*********** *********.*  .

53. spacer 3.1|642794|35|NC_011835|CRISPRCasFinder,CRT matches to MF155936 (Mycobacterium phage ZenTime222, complete genome) position: , mismatch: 8, identity: 0.771

gcctcctgatggatctccacgacgttgctggccct	CRISPR spacer
gattcctggtggatctccaccacgttgctgacggc	Protospacer
* .*****.*********** *********.*  .

54. spacer 3.1|642794|35|NC_011835|CRISPRCasFinder,CRT matches to MK494089 (Mycobacterium phage Ibrahim, complete genome) position: , mismatch: 8, identity: 0.771

gcctcctgatggatctccacgacgttgctggccct	CRISPR spacer
gattcctggtggatctccaccacgttgctgacggc	Protospacer
* .*****.*********** *********.*  .

55. spacer 3.1|642794|35|NC_011835|CRISPRCasFinder,CRT matches to NC_024135 (Mycobacterium phage Bernal13, complete genome) position: , mismatch: 8, identity: 0.771

gcctcctgatggatctccacgacgttgctggccct	CRISPR spacer
gattcctggtggatctccaccacgttgctgacggc	Protospacer
* .*****.*********** *********.*  .

56. spacer 3.1|642794|35|NC_011835|CRISPRCasFinder,CRT matches to MG925349 (Mycobacterium phage Mendokysei, complete genome) position: , mismatch: 8, identity: 0.771

gcctcctgatggatctccacgacgttgctggccct	CRISPR spacer
gattcctggtggatctccaccacgttgctgacggc	Protospacer
* .*****.*********** *********.*  .

57. spacer 3.1|642794|35|NC_011835|CRISPRCasFinder,CRT matches to KM591905 (Mycobacterium phage RonRayGun, complete genome) position: , mismatch: 8, identity: 0.771

gcctcctgatggatctccacgacgttgctggccct	CRISPR spacer
gattcctggtggatctccaccacgttgctgacggc	Protospacer
* .*****.*********** *********.*  .

58. spacer 3.1|642794|35|NC_011835|CRISPRCasFinder,CRT matches to MN735432 (Mycobacteriophage Whitty, complete genome) position: , mismatch: 8, identity: 0.771

gcctcctgatggatctccacgacgttgctggccct	CRISPR spacer
gattcctggtggatctccaccacgttgctgacggc	Protospacer
* .*****.*********** *********.*  .

59. spacer 3.13|643660|34|NC_011835|CRISPRCasFinder,CRT matches to NZ_CP045383 (Labrenzia sp. THAF35 plasmid pTHAF35_c, complete sequence) position: , mismatch: 8, identity: 0.765

tcgcaggtgaatatcggtggcggcggcttgtcgt	CRISPR spacer
tcacaggtgaatatcggtggaggcagatggcgga	Protospacer
**.***************** ***.* * *. *

60. spacer 3.20|642795|35|NC_011835|PILER-CR matches to MH001451 (Mycobacterium phage Nairb, complete genome) position: , mismatch: 8, identity: 0.771

gcctcctgatggatctccacgacgttgctggccct	CRISPR spacer
gattcctggtggatctccaccacgttgctgacggc	Protospacer
* .*****.*********** *********.*  .

61. spacer 3.20|642795|35|NC_011835|PILER-CR matches to MF155936 (Mycobacterium phage ZenTime222, complete genome) position: , mismatch: 8, identity: 0.771

gcctcctgatggatctccacgacgttgctggccct	CRISPR spacer
gattcctggtggatctccaccacgttgctgacggc	Protospacer
* .*****.*********** *********.*  .

62. spacer 3.20|642795|35|NC_011835|PILER-CR matches to MK494089 (Mycobacterium phage Ibrahim, complete genome) position: , mismatch: 8, identity: 0.771

gcctcctgatggatctccacgacgttgctggccct	CRISPR spacer
gattcctggtggatctccaccacgttgctgacggc	Protospacer
* .*****.*********** *********.*  .

63. spacer 3.20|642795|35|NC_011835|PILER-CR matches to NC_024135 (Mycobacterium phage Bernal13, complete genome) position: , mismatch: 8, identity: 0.771

gcctcctgatggatctccacgacgttgctggccct	CRISPR spacer
gattcctggtggatctccaccacgttgctgacggc	Protospacer
* .*****.*********** *********.*  .

64. spacer 3.20|642795|35|NC_011835|PILER-CR matches to MG925349 (Mycobacterium phage Mendokysei, complete genome) position: , mismatch: 8, identity: 0.771

gcctcctgatggatctccacgacgttgctggccct	CRISPR spacer
gattcctggtggatctccaccacgttgctgacggc	Protospacer
* .*****.*********** *********.*  .

65. spacer 3.20|642795|35|NC_011835|PILER-CR matches to KM591905 (Mycobacterium phage RonRayGun, complete genome) position: , mismatch: 8, identity: 0.771

gcctcctgatggatctccacgacgttgctggccct	CRISPR spacer
gattcctggtggatctccaccacgttgctgacggc	Protospacer
* .*****.*********** *********.*  .

66. spacer 3.20|642795|35|NC_011835|PILER-CR matches to MN735432 (Mycobacteriophage Whitty, complete genome) position: , mismatch: 8, identity: 0.771

gcctcctgatggatctccacgacgttgctggccct	CRISPR spacer
gattcctggtggatctccaccacgttgctgacggc	Protospacer
* .*****.*********** *********.*  .

67. spacer 3.32|643661|34|NC_011835|PILER-CR matches to NZ_CP045383 (Labrenzia sp. THAF35 plasmid pTHAF35_c, complete sequence) position: , mismatch: 8, identity: 0.765

tcgcaggtgaatatcggtggcggcggcttgtcgt	CRISPR spacer
tcacaggtgaatatcggtggaggcagatggcgga	Protospacer
**.***************** ***.* * *. *

68. spacer 7.1|1906890|33|NC_011835|CRISPRCasFinder matches to MT939492 (Xanthomonas phage Xoo-sp14, complete genome) position: , mismatch: 8, identity: 0.758

cgtccgagagtggattcgcggattgtcttgatc	CRISPR spacer
tcccagagcggggattcgcggattgtcttggcc	Protospacer
. .* *** * *******************..*

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

419179 : 427780

Pandoravirus(33.33%)

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_004268491.1\|419179_420310_+	3-deoxy-7-phosphoheptulonate synthase	S4W5F1	Pandoravirus	1.3e-78	44.5
WP_004268492.1\|420524_422528_+	acetyltransferase	A0A193GZ69	Enterobacter_phage	2.3e-22	33.0
WP_004268493.1\|422600_423848_+	3-deoxy-7-phosphoheptulonate synthase	S4W5F1	Pandoravirus	4.6e-85	49.2
WP_004268494.1\|423926_424619_+	5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase	NA	NA	NA	NA
WP_004268496.1\|424650_425874_+	two-component sensor histidine kinase	W8CYF6	Bacillus_phage	2.8e-26	29.3
WP_004268504.1\|425870_426578_+	response regulator transcription factor	W8CYM9	Bacillus_phage	2.4e-35	33.5
WP_004268505.1\|426664_427780_+	phosphate ABC transporter substrate-binding protein PstS	E3SII0	Synechococcus_phage	4.6e-20	29.7

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. NC_011835

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CRISPR-Cas detection and classification

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Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection