CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NC_014034	Rhodobacter capsulatus SB 1003, complete sequence	8 crisprs	csa3,RT,cas10,csm3gr7,cas2,cas1,WYL,cas3,cas5,cas8c,cas7,cas4,DEDDh,cas13a	2	26	8	2
NC_014035	Rhodobacter capsulatus SB 1003 plasmid pRCB133, complete sequence	0 crisprs	csa3	0	0	0	0

Results visualization

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CRISPR-Cas detection and classification

Crispr_ID: NC_014034_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_014034_1

677593-677806

Orphan

Consensus_repeat	Method
CACCTGATCGGTCGAGAGCGCCGCGGCCTGCGTCGTGGTCAGC	PILER-CR

2 spacers

The CRISPR arrays of NC_014034_1

>merge|NC_014034|1|677593-677806|PILER-CR
GCGGCCTGCGTCGTGGTCAGCGCCCGCACATCCTCGGTGCCAAGGCCGCGCAGCGCCGCGGTGGACAGCGCCGCCAGCGCCGCGGTGCCGATCGCGGCCACCTGATCGGTCGAGAGCGCCGCGATCTGCGTCGAGCCGAGCGCGCGGATCGCGGTGGCCGAAATGCCGCGCACCTGATCGGTCGAGAGCGCCGCGGCCTGCGCCGTGGTCAGCC

>NC_014034|1|1|677593-677806|PILER-CR
GCGGCCTGCGTCGTGGTCAGCGCCCGCACATCCTCGGTGCCAAG	GCCGCGCAGCGCCGCGGTGGACAGCGCCGCCAGCGCCGCGGTGCCGATCGCGGCCACCTGATCGGTCGAGAGCGCCG
CGATCTGCGTCGAGCCGAGCGCGCGGATCGCGGTGGCCGAAATG	CCGCGCACCTGATCGGTCGAGAGCGCCGCGGCCTGCG
CCGTGGTCAGCC

Protein	Signature genes	Signature genes Name	Protein_function
NC_014034.1\|WP_013066377.1\|686248_687448_-\|ABC-transporter-permease	unknown	unknown	gnl\|CDD\|225669
NC_014034.1\|WP_013066384.1\|698314_700087_-\|trypsin-like-peptidase-domain-containing-protein	unknown	unknown	gnl\|CDD\|379142
NC_014034.1\|WP_013066381.1\|691189_693862_-\|putative-virulence-factor	unknown	unknown	gnl\|CDD\|370827
NC_014034.1\|WP_181443875.1\|674573_675326_+\|ATP-binding-cassette-domain-containing-protein	unknown	unknown	gnl\|CDD\|226961
NC_014034.1\|WP_013066373.1\|676446_677172_+\|GNAT-family-N-acetyltransferase	unknown	unknown	gnl\|CDD\|225910
NC_014034.1\|WP_031320878.1\|673135_673843_+\|ABC-transporter-permease-subunit	unknown	unknown	gnl\|CDD\|226670
NC_014034.1\|WP_013066383.1\|696990_698307_-\|hypothetical-protein	unknown	unknown	unknown
NC_014034.1\|WP_013066379.1\|688183_690097_-\|VWA-domain-containing-protein	unknown	unknown	gnl\|CDD\|238119
NC_014034.1\|WP_013066382.1\|693871_696994_-\|virulence-factor-SrfB	unknown	unknown	gnl\|CDD\|377861
NC_014034.1\|WP_013066376.1\|684613_686245_-\|SUMF1/EgtB/PvdO-family-nonheme-iron-enzyme	unknown	unknown	gnl\|CDD\|335469
NC_014034.1\|WP_013066375.1\|683785_684583_-\|hypothetical-protein	unknown	unknown	unknown
NC_014034.1\|WP_013066367.1\|671477_672308_+\|MurR/RpiR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|224651
NC_014034.1\|WP_013066372.1\|675322_676450_+\|o-succinylbenzoate-synthase	unknown	unknown	gnl\|CDD\|239433
NC_014034.1\|WP_115503909.1\|669798_671013_-\|molybdopterin-molybdotransferase-MoeA	unknown	unknown	gnl\|CDD\|238452
NC_014034.1\|WP_013066380.1\|690080_691193_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|236090
NC_014034.1\|WP_013066365.1\|667934_669794_+\|HAMP-domain-containing-protein	unknown	unknown	gnl\|CDD\|223715
NC_014034.1\|WP_013066368.1\|672331_673108_+\|ABC-transporter-substrate-binding-protein	unknown	unknown	gnl\|CDD\|270420
NC_014034.1\|WP_023910978.1\|687441_688182_-\|ATP-binding-cassette-domain-containing-protein	unknown	unknown	gnl\|CDD\|213222
NC_014034.1\|WP_013066370.1\|673844_674543_+\|ABC-transporter-permease-subunit	unknown	unknown	gnl\|CDD\|226634
NC_014034.1\|WP_013066364.1\|666093_667926_+\|EAL-domain-containing-protein	unknown	unknown	gnl\|CDD\|238923

Protein	Function_ID	Function_description	E-value
NC_014034.1\|WP_013066377.1\|686248_687448_-\|ABC-transporter-permease	gnl\|CDD\|225669	COG3127, COG3127, Predicted ABC-type transport system involved in lysophospholipase L1 biosynthesis, permease component [Secondary metabolites biosynthesis, transport, and catabolism].	0.00548526
NC_014034.1\|WP_013066384.1\|698314_700087_-\|trypsin-like-peptidase-domain-containing-protein	gnl\|CDD\|379142	pfam13365, Trypsin_2, Trypsin-like peptidase domain. This family includes trypsin-like peptidase domains.	7.16316e-15
NC_014034.1\|WP_013066381.1\|691189_693862_-\|putative-virulence-factor	gnl\|CDD\|370827	pfam10139, Virul_Fac, Putative bacterial virulence factor. Members of this family of prokaryotic proteins include various putative virulence factor effector proteins. Their exact function is, as yet, unknown.	0
NC_014034.1\|WP_181443875.1\|674573_675326_+\|ATP-binding-cassette-domain-containing-protein	gnl\|CDD\|226961	COG4598, HisP, ABC-type histidine transport system, ATPase component [Amino acid transport and metabolism].	3.07789e-138
NC_014034.1\|WP_013066373.1\|676446_677172_+\|GNAT-family-N-acetyltransferase	gnl\|CDD\|225910	COG3375, COG3375, Uncharacterized conserved protein [Function unknown].	3.40666e-51
NC_014034.1\|WP_031320878.1\|673135_673843_+\|ABC-transporter-permease-subunit	gnl\|CDD\|226670	COG4215, ArtQ, ABC-type arginine transport system, permease component [Amino acid transport and metabolism].	5.05326e-86
NC_014034.1\|WP_013066382.1\|693871_696994_-\|virulence-factor-SrfB	gnl\|CDD\|377861	pfam07520, SrfB, Virulence factor SrfB. This family includes homologs of SsrAB is a two-component regulatory system encoded within the Salmonella pathogenicity island SPI-2. Among the products of genes activated by SsrAB within epithelial and macrophage cells is Salmonella typhimurium srfB. homologs are found in several other proteobacteria.	0
NC_014034.1\|WP_013066376.1\|684613_686245_-\|SUMF1/EgtB/PvdO-family-nonheme-iron-enzyme	gnl\|CDD\|335469	pfam03781, FGE-sulfatase, Sulfatase-modifying factor enzyme 1. This domain is found in eukaryotic proteins required for post-translational sulfatase modification (SUMF1). These proteins are associated with the rare disorder multiple sulfatase deficiency (MSD). The protein product of the SUMF1 gene is FGE, formylglycine (FGly),-generating enzyme, which is a sulfatase. Sulfatases are enzymes essential for degradation and remodelling of sulfate esters, and formylglycine (FGly), the key catalytic in the active site, is unique to sulfatases. FGE is localized to the endoplasmic reticulum (ER) and interacts with and modifies the unfolded form of newly synthesized sulfatases. FGE is a single-domain monomer with a surprising paucity of secondary structure that adopts a unique fold which is stabilized by two Ca2+ ions. The effect of all mutations found in MSD patients is explained by the FGE structure, providing a molecular basis for MSD. A redox-active disulfide bond is present in the active site of FGE. An oxidized cysteine residue, possibly cysteine sulfenic acid, has been detected that may allow formulation of a structure-based mechanism for FGly formation from cysteine residues in all sulfatases. In Mycobacteria and Treponema denticola this enzyme functions as an iron(II)-dependent oxidoreductase.	1.68675e-12
NC_014034.1\|WP_013066379.1\|688183_690097_-\|VWA-domain-containing-protein	gnl\|CDD\|238119	cd00198, vWFA, Von Willebrand factor type A (vWA) domain was originally found in the blood coagulation protein von Willebrand factor (vWF). Typically, the vWA domain is made up of approximately 200 amino acid residues folded into a classic a/b para-rossmann type of fold. The vWA domain, since its discovery, has drawn great interest because of its widespread occurrence and its involvement in a wide variety of important cellular functions. These include basal membrane formation, cell migration, cell differentiation, adhesion, haemostasis, signaling, chromosomal stability, malignant transformation and in immune defenses In integrins these domains form heterodimers while in vWF it forms multimers. There are different interaction surfaces of this domain as seen by the various molecules it complexes with. Ligand binding in most cases is mediated by the presence of a metal ion dependent adhesion site termed as the MIDAS motif that is a characteristic feature of most, if not all A domains.	6.15744e-15
NC_014034.1\|WP_013066367.1\|671477_672308_+\|MurR/RpiR-family-transcriptional-regulator	gnl\|CDD\|224651	COG1737, RpiR, Transcriptional regulators [Transcription].	2.51678e-28
NC_014034.1\|WP_013066372.1\|675322_676450_+\|o-succinylbenzoate-synthase	gnl\|CDD\|239433	cd03317, NAAAR, N-acylamino acid racemase (NAAAR), an octameric enzyme that catalyzes the racemization of N-acylamino acids. NAAARs act on a broad range of N-acylamino acids rather than amino acids. Enantiopure amino acids are of industrial interest as chiral building blocks for antibiotics, herbicides, and drugs. NAAAR is a member of the enolase superfamily, characterized by the presence of an enolate anion intermediate which is generated by abstraction of the alpha-proton of the carboxylate substrate by an active site residue and is stabilized by coordination to the essential Mg2+ ion.	5.71038e-171
NC_014034.1\|WP_115503909.1\|669798_671013_-\|molybdopterin-molybdotransferase-MoeA	gnl\|CDD\|238452	cd00887, MoeA, MoeA family. Members of this family are involved in biosynthesis of the molybdenum cofactor (MoCF), an essential cofactor of a diverse group of redox enzymes. MoCF biosynthesis is an evolutionarily conserved pathway present in eubacteria, archaea and eukaryotes. MoCF contains a tricyclic pyranopterin, termed molybdopterin (MPT). MoeA, together with MoaB, is responsible for the metal incorporation into MPT, the third step in MoCF biosynthesis. The plant homolog Cnx1 is a MoeA-MogA fusion protein. The mammalian homolog gephyrin is a MogA-MoeA fusion protein, that plays a critical role in postsynaptic anchoring of inhibitory glycine receptors and major GABAa receptor subtypes.	8.47974e-135
NC_014034.1\|WP_013066380.1\|690080_691193_-\|hypothetical-protein	gnl\|CDD\|236090	PRK07764, PRK07764, DNA polymerase III subunits gamma and tau; Validated.	0.000514147
NC_014034.1\|WP_013066365.1\|667934_669794_+\|HAMP-domain-containing-protein	gnl\|CDD\|223715	COG0642, BaeS, Signal transduction histidine kinase [Signal transduction mechanisms].	5.71652e-18
NC_014034.1\|WP_013066368.1\|672331_673108_+\|ABC-transporter-substrate-binding-protein	gnl\|CDD\|270420	cd13702, PBP2_mlr5654_like, Substrate binding domain of ABC-type histidine/lysine/arginine/ornithine transporter-like; the type 2 periplasmic-binding protein fold. This group includes uncharacterized periplasmic substrate-binding protein similar to HisJ and LAO proteins which serve as initial receptors in the ABC transport of histidine-, arginine, and lysine-arginine-ornithine amino acids. This group belongs to the type 2 periplasmic-binding fold protein (PBP2) superfamily, whose members are involved in chemotaxis and uptake of nutrients and other small molecules from the extracellular space as a primary receptor. PBP2 typically comprises of two globular subdomains connected by a flexible hinge and bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap. After binding their specific ligand with high affinity, they can interact with a cognate membrane transport complex comprised of two integral membrane domains and two receptor cytoplasmically-located ATPase domains. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis.	7.61229e-124
NC_014034.1\|WP_023910978.1\|687441_688182_-\|ATP-binding-cassette-domain-containing-protein	gnl\|CDD\|213222	cd03255, ABC_MJ0796_LolCDE_FtsE, ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein. This family is comprised of MJ0796 ATP-binding cassette, macrolide-specific ABC-type efflux carrier (MacAB), and proteins involved in cell division (FtsE), and release of lipoproteins from the cytoplasmic membrane (LolCDE). They are clustered together phylogenetically. MacAB is an exporter that confers resistance to macrolides, while the LolCDE system is not a transporter at all. An FtsE null mutants showed filamentous growth and appeared viable on high salt medium only, indicating a role for FtsE in cell division and/or salt transport. The LolCDE complex catalyzes the release of lipoproteins from the cytoplasmic membrane prior to their targeting to the outer membrane.	1.66699e-50
NC_014034.1\|WP_013066370.1\|673844_674543_+\|ABC-transporter-permease-subunit	gnl\|CDD\|226634	COG4160, ArtM, ABC-type arginine/histidine transport system, permease component [Amino acid transport and metabolism].	1.08686e-77
NC_014034.1\|WP_013066364.1\|666093_667926_+\|EAL-domain-containing-protein	gnl\|CDD\|238923	cd01948, EAL, EAL domain. This domain is found in diverse bacterial signaling proteins. It is called EAL after its conserved residues and is also known as domain of unknown function 2 (DUF2). The EAL domain has been shown to stimulate degradation of a second messenger, cyclic di-GMP, and is a good candidate for a diguanylate phosphodiesterase function. Together with the GGDEF domain, EAL might be involved in regulating cell surface adhesiveness in bacteria.	9.6173e-88

>NC_014034.1|WP_013066373.1|676446_677172_+|GNAT-family-N-acetyltransferase
MTAAVILRELAGVAELQQAERFQVEVWGEGERPDNSDIMLALQHEGALVAGAFAGDQMLGFLFGFPSATPGVQHSHRLAVSQKARGLGLGARLKWFQRDWCLARGITLVRWTYDPLRAINAGLNIAVLGATAREYLPDYYGPMPGINAGLPSDRVMAVWQLDAPQVVARAAGQSPTLPPAAATAGIPADIDALLQADPDRALAERMRLRAALQEAFAAGLAITGFDRQSCRYLLDRPAAAA
>NC_014034.1|WP_013066372.1|675322_676450_+|o-succinylbenzoate-synthase
MTQAFAGLTIDSAELRVVNLPLITPFTVSNQTLTDKTFPLLTLRADGVEGYGEGVMDPYPDYLEETLPGALAFLRDLILPQIVGKRIGNPAELTALLAPWRGHKMSKALVELAFWDLWTKALNLPLCAALGGLRDAVPVGVSLGITPIERTLERIAEAEAAGYKRIKLKVAQGHDLKLLEAVRREFPAVKLTVDANTAYGLADLATLRAMDRFDLDYIEQPLAVDDIHDHALVQREIATAICLDESIRTPVDCRKALAAGAARVINIKVGRVGGYSAAKAIHDVSEAFGAPVWCGGMLESGIGRAHNIHLATLPNFTKPGDTSSASRYFHRDIIAEPLEATGGLMPVPGNGAGIGVTLDRPFLNTVTRSTEEFRP
>NC_014034.1|WP_181443875.1|674573_675326_+|ATP-binding-cassette-domain-containing-protein
MLSAQDIHKSFGAQEVLKGITLGARNHDVISILGTSGSGKSTFLRCLNCLEIPNSGTVAVHGEEIVFRNGRIGDQRQIERLRRHLGMVFQQFNLWTHRTALENVMEGPVQVKRMAKAEARDLAEGLLARVGLADRMHHYPAMLSGGQQQRVAIARALAMEPDVILFDEPTSALDPELVGEVLKVMQDLAAEGRTMIVVTHEMAFARDVSTEVVFLNEGRIAEQGPPDRLFEHPETEVFARFISKTRRDIA
>NC_014034.1|WP_013066370.1|673844_674543_+|ABC-transporter-permease-subunit
MSLIESLSANLPKLLDGLETTLILTGLGAALAAVFSPGLALIRLSGPAPAKVLLRVYISFMRGTPLLAQLFLVFYGSGQFRAELTTLGLWSFFRDPFNCAVLVFVLNSCAYQTEILRGGLQAVPPGEIEAARAIGMTRAQVLARVTFPHAYRIAWPALGNEVILLMKASALASIVTVFDLMGRTRQIFSRSFEFSVYFEAAVLYLLITVLFVFLWRQIERRLTRPMRRTQGN
>NC_014034.1|WP_031320878.1|673135_673843_+|ABC-transporter-permease-subunit
METLFSYGPQGWGDELLAGLGVTLQLAAATLPLGLLLGFFVAALSLSRRPGLRAMGWGYTTVMRGMPEILTLFIVYNGLGLGLNRLLDAFAPQFGAVDFPPFAAGVIALALVFAAFAAEVLRGAFQSVPEGQVLAGLAIGMTGRQVFWRIKLPQLWRFALPGMGNLWLNLLKDTALVSVIALDDLMRATKVAVGVTKQPFTFYLAACLIYWALCLGSELVLARLEARANRGLRRV
>NC_014034.1|WP_013066368.1|672331_673108_+|ABC-transporter-substrate-binding-protein
MTLRSKLLACTLALVAMTGAAQAEKLRLGTEGAYPPFNFVQPDGTIAGFDLDIGLELCKRIGADCEVVAQDWDGIIPGLIAQKYDFIIASMFITEERKQQVAFTNPYYMAAMTHVVPKESELTEFSNETLSGKVVGAQSGTTQADYAVKMYPDADVRLYPTQDEASLDMASGRLDVMVGDMLPLLDFVEKSEDGKCCKLAGAPITDPAFVGEGVGIAVRQEDNALRERLNKALDEIRADGTYKKINDKYFSIDIYSMK
>NC_014034.1|WP_013066367.1|671477_672308_+|MurR/RpiR-family-transcriptional-regulator
MRAIAHFMLAQFQDLPFETAATLAAKVQVSEVSIGRFCRAIGYANFKDLKDHLKGDIGDQPWLIKDRLEALRRASDQRDERLSQGLKAEIAGLVGVYELARTEAWARVALRFARARRVLVAGFQTERGLAQYFAAQMQYVRPGVQSVDLSAGNFAEVLAETDAPEDTCLAIFEARRYARQALVLARAAQARGIAVTIFTDRYCSWGADHASEVFSVATEVNQFWDSTAHLALLGNLLINDIFLALGEGAETRLNEIARLYGAFSGHVGNPLTQVAQ
>NC_014034.1|WP_115503909.1|669798_671013_-|molybdopterin-molybdotransferase-MoeA
MLDLDSARRLACGLVAPIGDSETLDLAQAAGRTSATSLRAEIALPRAARSAMDGFALRTADLAAALTLPVAGTVAAGMQAPPLPDGAALRIFTGAQIPAGADAVVPVEEVTETGAEVQLTAAPAPGSHIRAVGSEQPLGGLLLRRGTRIRAHHIGLLASNGVAEVAVVRRPRLAILSTGDELHRPGAEAASRDTMPDVNRPMLIALAQGAGAEVDDHGILPDDAEATVAKFASLQGRYDLIVTTGAVSMGGRDHLRPALIAAGGQIDGWKVALKPGKPVMFGRLGNAAVTGLPGNPFSAMVGFTLFVSAQIARLKGAVPAPLFHCAGRAGFDWTRKPDRAEIFPIRLGNREIDGLPVVHRLGEGTSATLFPLAEADGLGFVPAETARVSVGTPICWQTFEAGAR
>NC_014034.1|WP_013066365.1|667934_669794_+|HAMP-domain-containing-protein
MRLRLLRLRAKSLRATLIFDLTVIGITAAALFAVVLGVMIRSSFGALESVEIGRDVDRARAALSADLVANEAHVLDWGLWDETFFYLRAFDRAYEDRNINAISFENAEISCAAFLRLDRSAQRAFCFDPGTGAPDPDLAAAVLTDFDTMALQPSRAGKTSSAGYWQQGGRLFAVASTPVRRSDGSGTAEGLLVFLHLIEAATLSQSLQVPVRLDFSAFSPVPVVVGEEDVLDVAVPVAMGSGPPMAMLRFQLPRLVLAAGERLRDLTVLALLGLLAALMALLGRRLSTQVLAPILAFRQHVVQIRQAGELVPIEGPPRTDEIGALHRDFNEMAAELEALRLAHAEQSFALGREQNATGLLHNLRNSLSPVRVILADLERHLLPDLPPEAGRARQELADPLTADDRRRRLVAYLEALDADRDQRGAEARALLQEAGRSLTEALEAMRAPRDPARVNRDEACDLGRALGHAATAARFVEGPKIDLSIDCPPGLQVRGNRVLLAQILENLVVNATEAIAASGRAQGRIAISVTPAEDGRRCSVTLADDGDGFDAATGARLFERGFSTRTDKHGGLGLHWCANTLSTLGGALSLTSPGKGLGAVARLDLPLTEASAGRLRPAG
>NC_014034.1|WP_013066364.1|666093_667926_+|EAL-domain-containing-protein
MTILVIDDEAAVRDAYRLLFSGTVSSRPVSRADALAEELFGAAVPQAAPGPSMGFEISLAAQGLEGVELAARALQEGTPFKVAFVDVRMPPGIDGKETARRLRALDPDLNIVIVSAWSDHSVTDITAVAGPADKIFYICKPFEPDEVRQMARALSERWDNDTRQLMFLRAKVAELAASEARAQHMASHDFLTGAANRMAFQNRLIERLEAGTNDLFVAFLDLDHFKHVNDTFGHDAGDEVIRMACAAFVSRAPAGTMVARLGGDEFGVLLTGMDRETAVATCQGLLETCSGDFSVFGNSVFIGASCGLVDGSCHPGCDAADLMRFADLALFAAKQDGGQTVRVFDKQLDASQQFRQRIEAGLFYALASEELSIHYQPIVASDTLDVVGYEALLRWNSRDYGTVPPGVFMPIAEESPVTLLLGDWVVERVLRDARGWPGLFTAINFSPRQFQRQDFVARLAAEARQNGLAPALIQIEVTETTLRAHARQSRKIVDELRAQGFRVAIDDFGTGASSIASLQDLAVDAIKIDRSFIEGMDRDRPSAAIVTALSHLAAGLGLEIVAEGVERISQRDVLRQLGCTHLQGFLFGQGQAVDRLLSASGGEPGRSAAG
>NC_014034.1|WP_013066375.1|683785_684583_-|hypothetical-protein
MMHPFLVTALMALALATGGGDPARAETSGEFGSVIRIPREAFGPDAGEITFDELPRGSRNPIYAPPTYGAPEGGVIVGFGGFFEGQAIGTAATCPPGAALTGCVIGTPLAPLRLAQTAPATQIRQDGANPHSPSLSGTPVFNGPVTMIFDRDVAGVGLAGGYFDTPQSTAIQAFDRQGRLIGGVRNLGTGMEYLALVTGDGSDRIAGVQFSLVGAEGAGFAIDDLSFGKSSQILRENVAELAAQEAQKRTPGLEAGIQLSQPQRN
>NC_014034.1|WP_013066376.1|684613_686245_-|SUMF1/EgtB/PvdO-family-nonheme-iron-enzyme
MRLVPLSAFALALAGLAAPQPGGADPAPGGPAPEGPAIDWPVALYDPGAATPGGSPADLVLPMPCGGAMAFQRVDVPSDAGDPLSDLRIRLGRSDPEKGYAEYLRQTWLRGGFSGTTPASTHYFIARYELTEGQFNALTRPCGKAGRKDRLAQGGLSWLAAVDLAGRYTEWLYGHAAAALPRQDGALPHLRLPTETEWEFAARGGARVDANQFAALRFFAEGALGDYAFHFAPGSARGTIGPVGLRRPNPLGLFDVYGNVEELMLEPFHVNIFGRDQGQVGGLVTRGGSVLSSAEQIYSAARTEYPPFQAQTGKATAPETFGLRLVLSMHVATSDAELTRLRDHWVARATEGEGGGGQGGAAARDQAGALAEIIENELDPQRRTALVALQADLRAARDSENAARRQSAGSTLLAGTIFKASLIQTDAEIGRLVYNVKTLIDLQAIAPDPQRQVQIETLGTRLRATRARQHEFLLSMSRALSTLAVDITEADSRAAYRELRESLLLSEEQALVVGLDQFWRDLAQYKLRPDMDQGALLALALTQ
>NC_014034.1|WP_013066377.1|686248_687448_-|ABC-transporter-permease
MLIVSLALRDLFRDRLFLLCNVAVMVGVLVPLLILFGVKNGVYSTLIGRMMADPASLQIDSQGNAELTEARIAPLRAWPEVAFVTPKVRSQFDYVTVHHAGPGVSLREALLIPSGAGDPNLPPGLVLGPAEVAVSAGLAQQMQIATGDTVDLVTQAETRPKQLRLPMTVRAVLPETVSAGRSVLAPFATLETVEAFYDAYALPEHGITEGRPLADRVATYAGVRIYARRLEDLGPLQQRVETALGLATSARSRDVAMLLGLGRNLDLALGLTTALACCGLAAALLFGFWSDAMRKRGTLAALAMLGLPARALALLPLVQALATALIGIAVSFLLYALAARIATRMFGAGLEAEGSIARISPAQGGAIILAILGLVLVSATLSAWAAQRVDPARTLREGT
>NC_014034.1|WP_023910978.1|687441_688182_-|ATP-binding-cassette-domain-containing-protein
MRTGGVLGIDQLATTLSKGERSFTLRVAALELVSGEVLCVTGASGTGKTLFLELLSLLRAPEPPAGYHWTAPDRRRTDLARLWRFGARGTGLARMRGALFGFVPQAGALVPFLSVRANVALTQRISGRRDPARVAALLDRLGLNALADLPPSALSIGQRQRVSIARALAHRPAFVIADEPTAALDPAAADAVMRLLLDTAREDGAGVVLSSHDLARIEGLGPRRLEFVARELRPGLVRSEAREVRC
>NC_014034.1|WP_013066379.1|688183_690097_-|VWA-domain-containing-protein
MTFAARTALIALGLALGLAGAELQARPLLMEGKQATFQRVLTRPGTQVLAAPDGAVLKTEAAFHPFYVYERQAEWLRVGTSASAGPTGWVRAGSVVEWKQNITAAFTNAAGRSRQVMLEDRATLEALMQDEDVRARLADLVAQSDSGHVDPAQKVVSVEPAEFINIREKLYLMPILSFEEILHPLTYEPDLLLELASIPQRAPSPPAAAPPSPFDAGVVFVIDTTRSMRPYINSTRAAVARIVQSLRATDLGARVQFGVIGFRDNPASDPAGIGYRTRTLAPLARRADQAEVLAALDAAAEVATVSTPGFNEDSMAGVEDAVGTIDWTGGGADPFEGRYVILITDAGPDAQDDPDARSQIGPAELRADAEAHGIAVLTLHLRTPAGGTAQHGYAEAAYRQLSGFGGRDFYYPIENGDEAVFAATVERMVVALTDTIRTAMGQQPALPPEAGGDARIAELGLAMQLAWLGGQPGVAPPDVLRGWMSEKAVEDPRRLAVEPRLLVSKNEMATMAELLTEIGTAGEQNRSAEETDAFFDQIQSVIARMAQNPDRLIDAEAGSLGGALEFLEDLPYRSQLLSIDRTIWAQSAVQRREILDGLHRKIVQYRKWLLDPTVWTPLEPGAPDGEYVFAMPFDVLP
>NC_014034.1|WP_013066380.1|690080_691193_-|hypothetical-protein
MTLTVQRDPGHGAGGHALLRVENGAALPDEVTVSVFETYSERWLAPSAQDGPAGISVGAPNWQAGRHLFGPYRVQRRDGAAEIAIGPEIVNKIEGYTQVRIVAGPVEGHLFWPNDIQPLDLARQRIGLQVARRTGAAQGPEPALRQAEAGVTAPPPLPPDAPMTEQDSAGIAAPEPRRRRWLWLVLALALVVLAALLGLGYSRYLQQQWPFSAGVEPPPAPETPPGPTPEPAPAPTPEPAAATPGQADPCTPEALGALGGITAITRAAGACGQRVGRDQMLIFVETAAQAGDAEALLLFGTLYDAAVTDPTVETQLGLSFADAPAQAADYYSRARAAGSAAAAGRLTAVCARLRAAEDTLSRGALDDFCR
>NC_014034.1|WP_013066381.1|691189_693862_-|putative-virulence-factor
MSSDSISERCITLAGLGRAALGWLDVQSNADRVGAEKGSMTRTLRRAVRRAERLGKSARTPMSVSVFGPSQAGKSFLVSVLARPADGRLVAQFGPTGLDYISELNPEGEGESTGLVTRFTCTRPEVPAGFPIRLSLLSEADLARVIANSFFMDGDKSEPPPEPADLTAHLDTFQTRRQPQPLPGMSDEDVIEIAEYIETNFARQSSYAAALKSFRDPAAALAPLLAPEDRAEFLSVFWGRHAPMTQLYRELAGSLAQIGHPEEIHVGLEAVVPRESSILDVKTLSDVLSPATGAQTIEVLTGAGLRAKLPRARICALAAELVLPMRDVPHPLFATTDLLDFPGARNRFNKALEVTLKDPETLPGLLLRGKVAYLFDRYVENQEITSMLLCVPDSNMETVDLPRLVSTWIERTHGARPDQRALVDCILFFVLTKFDKHLGDNAAAGGEASRFQRRMEASLLEKFSNGSDNWVDSWAAGRPFQNCFWLRNPNFYVDGLIDYDDDRRELRIRPEKAARIAELRQGCLEATAVRRHFADPEGAWDAALTLNDGGVRYLVEALTRVCKPDQKLRQIEQQLGRVVEDLLQTLAPHHVADDLHTRIEEKRKSCNAILDDLLVALQQHRFGAVLSALGVDQDAIAENIVRVPSSIRIGSAVSAAASTGSAGAGPVRPAAPARPGGATVARPGGGPAPATPEAAARGGEQVRTLTLEEFQAEQSILLWIEGIKAFRDDPARASGYGLRPQSIADLVAELIHAARRTGLSGRMAERLSELNFGLTVERLAPTAAVLTAEMINDFVATLGMSALPETARPTVTPEVGPPRPAFARRPGQDDVTGLPATPRATASDMWEDWAFALDAVMDANARDGLGGDIDIEQNLRLGAILEGMHREGRR
>NC_014034.1|WP_013066382.1|693871_696994_-|virulence-factor-SrfB
MSSLNRQNPLAKVPEWRDEVTLVPWSGLQILDFGFRQSDIEMRGMRFIERVMERPDIAAGLEERVLIPLSGDEELDAPLLRGARADDDEYSVSPVAAMDPFLERWLPVPVLRRKSVYGEGGEELYDPGPTAWALLRTVRLPVPDPETGHTHRVQLALDTALGAEKDGASYPAPDRSDALNSREFRFVSDPARMDWFLRRVETDAAGQQVDPQGWVSDLLDELFLAYKRAERPGRRITAENLPHRLEHWARYLAYLRLLDTAIRFPLLRLCNTIGEYDAVTPIDVDLVLDIGNSRTCGILIEHIPGEARLDPARSYPLEIRDLSRPELSGAGLFESRVEFSEFCMIEETKLRRAHRAGGFIWPSPVRIGAEALRLVAGDEGTEVASGLSSPKRYLWDESAVLQDWRFHNHSDPNNLPRAARSAMRFLNAAGDVIAQVKLEERSKLRRPGRTSTDPAGRPRFSRSSLFGFMLSEIIAHALVQVNAPAGRARRPQSDLPRRLSRIILTLPTATSIQEQAIMRSRAKGAVDLIWSMLGLTGAESSVSRKPEVSEEWDEASCTQLVYLYSEITQKFDGHIERFLRLKGRERVQAKGRPPEPSLRLACIDVGGGTTDMMVTTYFCRENRMLVPEQTFREGFRVAGDDLVERVIASIILPELQNAITAAGGKSAPNLMRELFAGDIGGQDQQLAQKRRQFGLRVLQPLALELIGACERAGEFDTMTIALDAVLGLTPRPEEDSAADDSPRGLPAALIDYLETPARASGAETFRLAGTVLHCDRQKVDAITRETFQKALGNLAEVIDHLGVDIVLMTGRPSRLPALRTIFEEMLVVPPHRLILMNDYRTGRWYPFRDPVSQRIGDPKSTVAVGGMLIALSESRIPNFKVATAAFKMRSTAVFIGEMDASGQIPDDRVLFGGTELDPQGRDTGGSARLRMFTPIYLGFRQLPLPRWTTTPLYRLDLANAAAQRHKPPLVVTLERAEFDADPDDTRPDTALRREAAREAFEVSEIEDGDGQTVRRDQVVLKLHTLGAADDYWIDTGVFKF
>NC_014034.1|WP_013066383.1|696990_698307_-|hypothetical-protein
MSDGLITTTSSEGLQALGSAAQRSWELITGTLCDRLDRDHAAIFAEPVSTHGGARIEWYVPPGCSGRPVPLAALSGPEAEEIRARLAAIHGRILALADQISAQNGAQAGPPTGAQSSADNYWLAEALRNAIEVPDQDAIWALRQDDGSLRPILVNWGRLLDTTRAARGALSVLAPNRRPPAAAAAMAATALPAPAFPAAETHWLAAPPPPETPRPWGHWLVLLGWLLVAALIAAVLWLLIAPCGLRPGFLGFCPAPAAATAPALQAEALRAEIAQLTDRLALSERMCLNARKRAEAPAAPESEIADLDRRLQARGAAAGAMTISLVWSGRDDVDLRVSCPSGQIADLQRRPNDCGGLLDVDANYPALIAVEDPVENIHFNTPVPGRYRVQVARLTDVPPRGDLSFGVVLRRAGTPEQRREGTFRGREKRWSTEFEISR
>NC_014034.1|WP_013066384.1|698314_700087_-|trypsin-like-peptidase-domain-containing-protein
MAEHFLFRSSLQAEDCLSVAGQPVLERHAALHELLTARLGAEAAELFAEPFVSRGAAGAALNVAWHSVHAGEARPLADLDPALRRAVEDRLLRLLPKIEALATDPGLTPDLAALVRAALSLSQAADVRAINGVPVLVNWGVRPRGGAPALAGFMRGDAAAAGPAAAAPGPATVPPPIPDAAQPGPAMSAGLPPAATRPVLPLAAWLPLPILLVLLCLVLIWLLLPGTRVFPPQSVVRDADVSAAQETELGALRDRRDALRQALAGAQCREDGVLVLPGNRTPEGLSLPAPGAAPEQGQVAPDSPVAPAPERALLPAAPGAPAETDTLLARIEAATVLVIAPGAQGVSTGSGFAVGPGLIVTNQHVIEDLGPEGAFVVNKLLGQPQPAQVLKTAGPLEAVGADFALLKIGSTALPALPLADPAASLKLNHVVAAGFPGDVMETDAAYEALLRGDGAAMPGLVVVDGTVNAEQPLQGATETLLHSAPLAQGNSGGPLVDFCGRVLGVNTFVRQGPLRTLNFALSAAGLAEFLAGTPAAVTPDRASCQPTVAPASATPAPTPAPAPAPAAPAPGAPAGAPDGTVPATPGPGGE

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Crispr_ID: NC_014034_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_014034_2

1349552-1349802

TypeIII

Consensus_repeat	Method
GCCCAGATACCTCTCCCGCCAGTAAGCGGATTGAGAC	PILER-CR
ACCTCTCCCGCCAGTAAGCGGATTGAGAC	CRISPRCasFinder
ACCTCTCCCGCCAGTAAGCGGATTGAGAC	CRT

3 spacers

RT,cas10,csm3gr7,cas2,cas1,WYL

The CRISPR arrays of NC_014034_2

>merge|NC_014034|2|1349552-1349802|PILER-CR,CRISPRCasFinder,CRT
GCCCAGATACCTCTCCCGCCAGTAAGCGGATTGAGACGTCGATCCGGTCTCAAGCTGCGCCTGCGTCACGGCCCAGATACCTCTCCCGCCAGTAAGCGGATTGAGACACGGGGGCGGCGGCGAGGCAGGCGAAGGCGGCGGCGCCCAGACACCTCTCCCGCCAATAAGCGGATTGAGACTGCGTCACCTCCGATCAGCGCGAGGATGCGATCAGGCCCAGACACCTCTCCCGCCAGCAAGCGGAGTGCGTG

>NC_014034|2|2|1349552-1349730|PILER-CR
GCCCAGATACCTCTCCCGCCAGTAAGCGGATTGAGAC	GTCGATCCGGTCTCAAGCTGCGCCTGCGTCACG
GCCCAGATACCTCTCCCGCCAGTAAGCGGATTGAGAC	ACGGGGGCGGCGGCGAGGCAGGCGAAGGCGGCGGC
GCCCAGACACCTCTCCCGCCAATAAGCGGATTGAGAC

>NC_014034|2|1|1349560-1349802|CRISPRCasFinder
ACCTCTCCCGCCAGTAAGCGGATTGAGAC	GTCGATCCGGTCTCAAGCTGCGCCTGCGTCACGGCCCAGAT
ACCTCTCCCGCCAGTAAGCGGATTGAGAC	ACGGGGGCGGCGGCGAGGCAGGCGAAGGCGGCGGCGCCCAGAC
ACCTCTCCCGCCAATAAGCGGATTGAGAC	TGCGTCACCTCCGATCAGCGCGAGGATGCGATCAGGCCCAGAC
ACCTCTCCCGCCAGCAAGCGGAGTGCGTG

>NC_014034|2|1|1349560-1349802|CRT
ACCTCTCCCGCCAGTAAGCGGATTGAGAC	GTCGATCCGGTCTCAAGCTGCGCCTGCGTCACGGCCCAGAT
ACCTCTCCCGCCAGTAAGCGGATTGAGAC	ACGGGGGCGGCGGCGAGGCAGGCGAAGGCGGCGGCGCCCAGAC
ACCTCTCCCGCCAATAAGCGGATTGAGAC	TGCGTCACCTCCGATCAGCGCGAGGATGCGATCAGGCCCAGAC
ACCTCTCCCGCCAGCAAGCGGAGTGCGTG

Protein	Signature genes	Signature genes Name	Protein_function
NC_014034.1\|WP_031321060.1\|1356525_1358133_-\|CRISPR-associated-endonuclease-Cas1	cas1	cd09634_cas1_CAS-I:CAS-II:CAS-III:CAS-V	gnl\|CDD\|376633
NC_014034.1\|WP_013067005.1\|1347481_1349284_+\|hypothetical-protein	unknown	unknown	unknown
NC_014034.1\|WP_013067019.1\|1364838_1365822_-\|WYL-domain-containing-protein	WYL	pfam13280_WYL_CAS-I:CAS-III	gnl\|CDD\|379100
NC_014034.1\|WP_013066998.1\|1340003_1340639_-\|recombinase-family-protein	unknown	unknown	gnl\|CDD\|239737
NC_014034.1\|WP_148214845.1\|1344674_1345400_-\|hypothetical-protein	unknown	unknown	unknown
NC_014034.1\|WP_013067004.1\|1347027_1347285_+\|helix-turn-helix-transcriptional-regulator	unknown	unknown	gnl\|CDD\|238045
NC_014034.1\|WP_013067006.1\|1349931_1351398_+\|hypothetical-protein	cas10	cls000707_cas10_CAS-III	unknown
NC_014034.1\|WP_013067008.1\|1353037_1355665_+\|RAMP-family-CRISPR-associated-protein	csm3gr7	cd09726_csm3gr7_CAS-III-D	gnl\|CDD\|187857
NC_014034.1\|WP_013066997.1\|1337341_1339951_+\|DEAD/DEAH-box-helicase-family-protein	unknown	unknown	gnl\|CDD\|223989
NC_014034.1\|WP_131618292.1\|1346290_1346500_+\|hypothetical-protein	unknown	unknown	unknown
NC_014034.1\|WP_115503936.1\|1341655_1343008_+\|RNA-directed-DNA-polymerase-(reverse-transcriptase)-protein	RT	pfam00078_RT_CAS-I:CAS-III	gnl\|CDD\|275209
NC_014034.1\|WP_013067003.1\|1346637_1346949_-\|hypothetical-protein	unknown	unknown	unknown
NC_014034.1\|WP_013067017.1\|1363824_1364118_-\|hypothetical-protein	unknown	unknown	unknown
NC_014034.1\|WP_013067015.1\|1361402_1361615_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|235095
NC_014034.1\|WP_157834357.1\|1341064_1341655_+\|SLATT-domain-containing-protein	unknown	unknown	gnl\|CDD\|375597
NC_014034.1\|WP_013067002.1\|1345539_1345941_-\|hypothetical-protein	unknown	unknown	unknown
NC_014034.1\|WP_013067018.1\|1364117_1364585_-\|hypothetical-protein	unknown	unknown	unknown
NC_014034.1\|WP_013067009.1\|1355661_1355952_-\|CRISPR-associated-endonuclease-Cas2	cas2	pfam09827_cas2_CAS-I:CAS-II:CAS-III	gnl\|CDD\|378256
NC_014034.1\|WP_013067016.1\|1361707_1363828_-\|relaxase/mobilization-nuclease-domain-containing-protein	unknown	unknown	gnl\|CDD\|367497
NC_014034.1\|WP_013067007.1\|1351394_1353041_+\|hypothetical-protein	csm3gr7	cls000708_csm3gr7_CAS-III-D	gnl\|CDD\|187857

Protein	Function_ID	Function_description	E-value
NC_014034.1\|WP_031321060.1\|1356525_1358133_-\|CRISPR-associated-endonuclease-Cas1	gnl\|CDD\|376633	pfam01867, Cas_Cas1, CRISPR associated protein Cas1. Clustered regularly interspaced short palindromic repeats (CRISPRs) are a family of DNA direct repeats found in many prokaryotic genomes. This family of proteins corresponds to Cas1, a CRISPR-associated protein. Cas1 may be involved in linking DNA segments to CRISPR.	1.80138e-70
NC_014034.1\|WP_013067015.1\|1361402_1361615_+\|hypothetical-protein	gnl\|CDD\|235095	PRK02983, lysS, bifunctional lysylphosphatidylglycerol synthetase/lysine--tRNA ligase LysX.	0.00387258
NC_014034.1\|WP_013067019.1\|1364838_1365822_-\|WYL-domain-containing-protein	gnl\|CDD\|379100	pfam13280, WYL, WYL domain. WYL is a Sm-like SH3 beta-barrel fold containing domain. It is a member of the WYL-like superfamily, named for three conserved amino acids found in a subset of the superfamily. However, these residues are not strongly conserved throughout the family. Rather, the conservation pattern includes four basic residues and a position often occupied by a cysteine, which are predicted to line a ligand-binding groove typical of the Sm-like SH3 beta-barrels. A WYL domain protein (sll7009) is a negative regulator of the I-D CRISPR-Cas system in Synechocystis sp. It is predicted to be a ligand-sensing domain that could bind negatively charged ligands, such as nucleotides or nucleic acid fragments, to regulate CRISPR-Cas and other defense systems such as the abortive infection AbiG system.	7.20468e-30
NC_014034.1\|WP_013066998.1\|1340003_1340639_-\|recombinase-family-protein	gnl\|CDD\|239737	cd03768, SR_ResInv, Serine Recombinase (SR) family, Resolvase and Invertase subfamily, catalytic domain; members contain a C-terminal DNA binding domain. Serine recombinases catalyze site-specific recombination of DNA molecules by a concerted, four-strand cleavage and rejoining mechanism which involves a transient phosphoserine linkage between DNA and the enzyme. They are functionally versatile and include resolvases, invertases, integrases, and transposases. Resolvases and invertases affect resolution or inversion and comprise a major phylogenic group. Resolvases (e.g. Tn3, gamma-delta, and Tn5044) normally recombine two sites in direct repeat causing deletion of the DNA between the sites. Invertases (e.g. Gin and Hin) recombine sites in inverted repeat to invert the DNA between the sites. Cointegrate resolution with gamma-delta resolvase requires the formation of a synaptosome of three resolvase dimers bound to each of two res sites on the DNA. Also included in this subfamily are some putative integrases including a sequence from bacteriophage phi-FC1.	6.61007e-30
NC_014034.1\|WP_013067007.1\|1351394_1353041_+\|hypothetical-protein	gnl\|CDD\|187857	cd09726, RAMP_I_III, CRISPR/Cas system-associated RAMP superfamily protein. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; RAMP superfamily proteins.	3.78656e-09
NC_014034.1\|WP_013067004.1\|1347027_1347285_+\|helix-turn-helix-transcriptional-regulator	gnl\|CDD\|238045	cd00093, HTH_XRE, Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators.	3.89223e-11
NC_014034.1\|WP_013067008.1\|1353037_1355665_+\|RAMP-family-CRISPR-associated-protein	gnl\|CDD\|187857	cd09726, RAMP_I_III, CRISPR/Cas system-associated RAMP superfamily protein. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; RAMP superfamily proteins.	4.32316e-11
NC_014034.1\|WP_115503936.1\|1341655_1343008_+\|RNA-directed-DNA-polymerase-(reverse-transcriptase)-protein	gnl\|CDD\|275209	TIGR04416, hypothetical_protein, group II intron reverse transcriptase/maturase. Members of this protein family are multifunctional proteins encoded in most examples of bacterial group II introns. These group II introns are mobile selfish genetic elements, often with multiple highly identical copies per genome. Member proteins have an N-terminal reverse transcriptase (RNA-directed DNA polymerase) domain (pfam00078) followed by an RNA-binding maturase domain (pfam08388). Some members of this family may have an additional C-terminal DNA endonuclease domain that this model does not cover. A region of the group II intron ribozyme structure should be detectable nearby on the genome by Rfam model RF00029. [Mobile and extrachromosomal element functions, Other].	4.15975e-30
NC_014034.1\|WP_157834357.1\|1341064_1341655_+\|SLATT-domain-containing-protein	gnl\|CDD\|375597	pfam18160, SLATT_5, SMODS and SLOG-associating 2TM effector domain family 5. The SLATT domain contains two transmembrane helices. SLATT domains are generally predicted to function as pore-forming effectors in a class of conflict systems which are reliant on the production of second messenger nucleotide or nucleotide derivatives. SLATT domains are predicted to initiate cell suicide responses upon their activation. This SLATT family contains an additional C-terminal alpha-helix, and strictly associates with a reverse transcriptase domain, part of a predicted retroelement with diversity-generating potential.	4.36229e-43
NC_014034.1\|WP_013066997.1\|1337341_1339951_+\|DEAD/DEAH-box-helicase-family-protein	gnl\|CDD\|223989	COG1061, SSL2, DNA or RNA helicases of superfamily II [Transcription / DNA replication, recombination, and repair].	9.60605e-09
NC_014034.1\|WP_013067009.1\|1355661_1355952_-\|CRISPR-associated-endonuclease-Cas2	gnl\|CDD\|378256	pfam09827, CRISPR_Cas2, CRISPR associated protein Cas2. Members of this family of bacterial proteins comprise various hypothetical proteins, as well as CRISPR (clustered regularly interspaced short palindromic repeats) associated proteins, conferring resistance to infection by certain bacteriophages.	5.87522e-19
NC_014034.1\|WP_013067016.1\|1361707_1363828_-\|relaxase/mobilization-nuclease-domain-containing-protein	gnl\|CDD\|367497	pfam03432, Relaxase, Relaxase/Mobilisation nuclease domain. Relaxases/mobilisation proteins are required for the horizontal transfer of genetic information contained on plasmids that occurs during bacterial conjugation. The relaxase, in conjunction with several auxiliary proteins, forms the relaxation complex or relaxosome. Relaxases nick duplex DNA in a specific manner by catalyzing trans-esterification.	2.46547e-20

>NC_014034.1|WP_013067005.1|1347481_1349284_+|hypothetical-protein
MTIDLGPIQTRAAQEIAVGGLRVWYHLPFALLDDGIDPARHGWVAEKPKGTLQQQFYFHPFVSNALWDRADGGVSALFDLYRKPAFEFRHFTADFDSTDWKEMQDGKSEQLLCRRTFRGTVRTVELRRLREPAGSGRQSGLHGFAMLVVSVDFLCAAYGEYPRDKVKDPAPFAPLTLADAQDALDLSRRIFPRWHFYGEDALPGDALTRVPCFGPAPSRPEMDEGVRKGKTQLMPWVRELVAPFTLSEPDSRHFGDERAFITSAVLLGDGSEQEAEAFTLMTRVKDSDLMRLAEVDRRGTGYSYNKPFLDALAPGYFYTRQAPDGPTGTGNSTLYITASHHFCALGAGGYMRNVILGNGIPGHHDMGHAEEYYRHMQFLCVFEFFRLLQFSQTLSELVRSQRERGAIGDKSRTAVADFGQRLMRIRDEFLDFTHLHHFSNISSQLQPREMFDRLYAAFGIPAMFAEVEKELEAATSFHEMHTNAEAREDAARLNKLVSVGVPLSLLVGAGGMNIFIGDKAPFGLHAIVPALPGQTDAAGPPDGWLQLLQLSVLVAIIAGIWALAERVYFRDKRSFWGWLAYGAAAAAFAGSEALHLWPAP
>NC_014034.1|WP_013067004.1|1347027_1347285_+|helix-turn-helix-transcriptional-regulator
MPRTIHTEGQRALCEAIAAARREKGLNQADLARELHCQQSLIARIESGERRIDVLEFIKIFRALGVSPAEALRRVGEQIPADQGI
>NC_014034.1|WP_013067003.1|1346637_1346949_-|hypothetical-protein
MQDTDDLDLEPVTFLVEAEIAARRAFDARVAREPGFSALARKRVSRYLDNPIWRGLVELHINGATSFEHGLMLRGAGLVRPARFFVRRGSEVRILSLRQISRI
>NC_014034.1|WP_131618292.1|1346290_1346500_+|hypothetical-protein
MLAMHFPSPQPMEVGLERNGEAAVASQEDWQLRSASSYGPLLGGDFFFRKQPYNFDIGTAKAEFKMEAD
>NC_014034.1|WP_013067002.1|1345539_1345941_-|hypothetical-protein
MCAKPFHANDLGNHALREAQRVATALAEAGPSATDLISAPTMHAWIGVQDTRFGGAILMGRPEGHPVCRGPVSHTSRLCGLDPDLTWARTMTRWYRLGVPADPGEVSFYALRYGIPRDLILGPDRLRDAISWV
>NC_014034.1|WP_148214845.1|1344674_1345400_-|hypothetical-protein
MRRLFSFLLFPSLPICAAPRALFLLFPLTSLSVFSLFSPLSQKSSGFSGRTVRVKGRAAPPGHGMSNSFSQISSRTGGYQHLSAVARPRPPKARSGPNRIRPILVSPPETADPDHWPRFFVGRDLGQTGAQSGMDGGQQTGRKAGGSVPPARPALRPGQGDLQRLEAALRIVAGLVIENPVYAPIFRRLEREIALEKQAQAADVIARARAVIAQNESNALIDQNEIGTSNSAACSSEAPKP
>NC_014034.1|WP_115503936.1|1341655_1343008_+|RNA-directed-DNA-polymerase-(reverse-transcriptase)-protein
MLQMGSKETFCALFNPKELQDIFDKSVALKGAIGRDGQSVEAFRGRIKDELSLIERKALNCTYKFTAYSEKLVSKGAGKRPRQLSKPTVRDKVTLKALSKILVSLFPSAIPATPHSIVRDALGIIRGEFGEFYYVRLDIQEFFPSIDHDILMRLLRRRIRYRPILHLVKDAIRTPTGVKKSEGSLNQVGIPQGLSISSALASIYLADMDEELSSLCSGRYFRYVDDVLFVCKPSEAEEIARRATEILQKKRKISCHPVGTGGKSVIVPGAQGIDYIGYHFSPGLLRVRTSSVRKYLGVMVTEFSKCKQAGLAGSRLWRLNLRITGCIFDGKRIGWMFFFSQTEDVSQLKRIDAFIKSRAGLVSGQAEASRVKRLVRAYHEIKYNLHGTKYIPNFDKYGLEDKRRDICLLAPHLFSARVESMTADEINAAFRTCINKEISDIEKDLLEAFS
>NC_014034.1|WP_157834357.1|1341064_1341655_+|SLATT-domain-containing-protein
MTNVSGINSPTPDKSLADKIWLTSHCRMNAERRNRRYEIWATIELSSVSVGIIGLTTFRDRLGAFPVDEYTLILSIMTLVISTLIAGAKFGERAATFRECYLQLERLNASKQDLQEKTSEYNAILASYPNHSDIDYTSLIISRTLWRNQELCDPRGRSITWTWGTLGSWILYIFVEVLVYLVLPALVFLPAAVLAW
>NC_014034.1|WP_013066998.1|1340003_1340639_-|recombinase-family-protein
MSRTVLYARVSTADQTLSHQRTQAEMAGFVIDEVVADHGVSGVSTRLRERAEGRRLFDLLRKGDVLVVRWLDRLGRNYTDVTEVVRHFMQQGVIVRTVINNMTFDGSTSDPVQQAVRDSMIAFMAATAQAQAEALREAQRAGIEAAKANGNRYRGKKPTFDRSKLIVVRDMLDNGAGASEISKATGISRQAILRIRENPAQAEAALARWGM
>NC_014034.1|WP_013066997.1|1337341_1339951_+|DEAD/DEAH-box-helicase-family-protein
MRTLDYQERVLRTLDDYLDELKAQKVQADQIDAVRAANPNLAIPPLDFCAKAWENLNAVKPLPVRKFKDGTVVPFSPRVDGIGRAVPNVTFKVPTGGGKTWLAVNAVSRIMGRYLGKNEGFVLWVVPNEAIYTQTLKRLKDRQHPYRQALDRAAAGRVKVMEKGDRLDARDVETHLCVMVLMLQAANRQTQETLRMFRDRGDVHGFFPPEGDQAAHAAELKAVPNLDGYQGMFPMVKDSLGNALRKIRPVVVMDEGQKATSDLANKTLYDFNPLFVLELTATPKDVTAKGGGARYANLLVEVTGRELHAEDMIKMPLNLEPRQGTDWRGTLTAALDRLNTLQAAADAYRADRGELAYIRPIMLVQVERTGKDQRDGVHIHAEDVKEWLLQAGLDEAQIAIKTAEQNDLSQPENQDLLSPANRVRVIVTKAALQEGWDCPFAYVLCSLAAASNLSAMTQLVGRILRQPYALKTKVSALDECYVITHHAGTREVVEAIKAGLEKDGLADLVIEVPAGTGATAPGTQRRVERRAEFKSLKVYLPKVLCDDGGALRDLDYETDILSAIDWRDYDPSAVAQAIPENPLLAAAQLQRISLTDGGSDYFRQEEIAAASETLRYDPSYAVRVISDLVPNPFVARSILGRLVDVLKARGFDDKKLGAASGVIVDALRLALDKERTTRAEALFKAGVKAGRIQFRLRLDGNNWVMPETITTFEPDLSPHMTGGDGGPLKRSLFSPVFRNELNTEEQGVAVHLDGEAAVKWWHRNVAKTNYGIQGWQRGRIYPDFIFATGCAGGNGRIVMLETKGDHLQNPDTDYKREVLDFLTENFSWDQAVPAGQLQITQTGETLECALVLMRDIPARLPVLIAGHEP
>NC_014034.1|WP_013067006.1|1349931_1351398_+|hypothetical-protein
MFLYLEGVNLYATIYDTEDLSTIRGGSMALETLAQRAQAALGGTLRGQGASIALLEFSGPPPEEDKIRAFLSATPQCHFTLTWGTGETEAQAIKAARDRQFSQLATVVLPAIMAGVRPCAIDHTRPGTISDFDLKEQKERFLCASVADRRKIGRVGRPQLFRKRQPQPPQSFEDIAPEDAPGLKPNVRGKIAVIVADGMGGGDLAKAYGTDTAGFSTAMAAFRARLAEAIEDWASAEGLIYTDKAGVAHARVDVLMWGGDDMTFVVPASHVLGFLAALQGVLGAPFDKDKGTARFGHRIGCVIAQRKTPIRLLKKLAGSAEAALRDAVTPEMRKAGVSVVSLDVFESAPLPFASILDHRRTVYGQGYRSGADAVLLSHVAKMAAALRELDDEEGAILKMSQIYRLLDVARLSRRDLCSKAADEAIAEAMKGHFERVKGTPPDMAAWENGWTGQASRGLALLLAQVAQLQPYAQPFTDERARVLSEAVQ
>NC_014034.1|WP_013067007.1|1351394_1353041_+|hypothetical-protein
MTAPLVFDVTLSLKAPFLFPGQDPGRFGYDRVALRDLDGRPIIPQDQIKGLIRHGLTIMGETELVEGLMGKGSADARKDSGGAFEPAKGRMFLTDLRCTIEPDLRSTDYHRVQIDDESGAAKQGHLLRIEQVFAPEREVAFSGRITLFPTAKAPDAQALALLLAAALQCKRHIGAMASIGFGEVSGCSVEPALEAEEACKLPADPVGRFLWRFRVDRPYLVDAIRTDNGYIGQPTIPGGALKGLVARCAEMRGNPLDAQSLSDTVFGHATQHVAQALPLSVVCLKEKGAETCRDLAGKGALPDGVTLQIDWKAVHEAACVAGFKHCLAPPPRHVERVHTQIDATTGAAQDENLFSTTAVVPGNDVFTALVDTSALSAENARAVLSALCAPMPGLGRTDARVEPIDFVTDKAPSPVTGTVALVLQTKAWIEVDPALLRHDPLAAYAPAFKAFLPNSTLLEVHAAQELLGDYLARRFTGQSGYMPWLVTSRGSVFVLDVAPSDQAELAALQRKGLCSATRDGTALDWQSCPFVAENGYGAFLLSSVGGSR
>NC_014034.1|WP_013067008.1|1353037_1355665_+|RAMP-family-CRISPR-associated-protein
MKHLRRYRLEWTVLTPLHVGAGQSELRAHDEEDASEVALIARDHAGKPWIPGSTIKGALGATCTDVKVRLFGKPHEKGSQQARGTLTFSGARYVSKAGSSASFELAQTSVAVGTGVAAANKLYRRDFVPEGVTFTSDIDVESGDEPTVQADCAALETLLALAASSEGLNLGANKADDLGRLQITRIERAESRFGPTGWTAQTFAPHTIAASAPVRAPLFGLRMVCPGPFLSKGGQTDNETQPLMDAAGKAPRIMGTAVSGALRKRAEWLWALHLHRGGGAEMKSCKTSAGPRDLDPVQRLFGYEGRRGLLQVSPRNVSAKGSCQIPGVSLDAMTAAPRDGLLFFYHAHHGVTFDLSISTRADLDAAETNLFDLLKADLEANGLKLGMGTTKGFGWFCSDQDPILKHYSEKQTEALKLKSKEDPADHYAEAELPSNLVTIPYRLSRIDPNVIQLPEQRVSDRFSNHALLSKPMPAAASGHIDLVWHVETPVLVAAQTHDHTKPPKDVPFQKIGDTFAIPGSTIKGMLRAELERRVNARAYRIIENLLAITDDPEAERPHLDAKKQLAAFKAHRPDVNENYTPDFAEALFGFVREPESDDKSRSRHEALHLKARISCGMAWLVSEYDADKSRDELYVIAAAEPRPISKFYDHFGRKAYLVDNASAADVVARLKAAERKLDKYASPLKLLHPKQGQNLLFAQRIYLHNMTEAEIGAFLTVLTLDFTLRNRFLIGRARAFNAGKCFPAKIKLTLTPNDAGADYPARGGSKADMRMIGQSATPFLSAFGKFVNSGEDPSTARDPALARSMGFAAKEFNAAHDPLFGDYLRKRSRLDDGKIYYQQTSDDPKNRNFSASDRQKAFEANNGRLAAVLKKTWRD
>NC_014034.1|WP_013067009.1|1355661_1355952_-|CRISPR-associated-endonuclease-Cas2
MPRAEMLMVFTYDVSQDRKRRRVARILEGAATRVQYSVFEARLSEQRAAALAQRVAAELAPGDSLRVYAIGASGETRTRTYDDAAPIEPPGNYWIV
>NC_014034.1|WP_031321060.1|1356525_1358133_-|CRISPR-associated-endonuclease-Cas1
MAMAVDRISALRRMGYTWVVEADIEKAFDRIPHDPVLEALDTALDPAPGTRALIDLVGLWLAHGSGQLGTPGRGLAQGSPLSPLLSNLFFDGLDDRFDSGAARIVRFADDFVILARSEAGAEEARALAEEFVAGHGLRMVSRETRVVGFDRGFQFLGQLFVRSLVLPAPDEPDPDASAVMRELAEADAATAEAVAAGYDPGARVLYLVEPERRLSLRAESFAVLDGGGSLLLSLPPARVNRIELGPGAVVDDPVWRHALATDTTLAFLDGHGKTQGYLAPPQPAEAQLQLAQAALVLHPERRLALARVLVGARLRNQRARLAVLNRSAKATEVDRAIAALGRAIRGLAAPMPDLDTLRGHEGRAARIYWPALARLCTAHKGPFLCERPAKTPLNAAINYLTALLARDIRAALIGAGLHPGFGVLHQAQDRGDAAVYDLMEVFRATLSEGLAVSLFNRRRLREEMFEPQGDSLRLLTPGRRALITGYEEALERVIRSSQTGQRHALRRIMLEEARALARHCRSPETVPYLPQLQDY
>NC_014034.1|WP_013067015.1|1361402_1361615_+|hypothetical-protein
MDDGSGVALIGLIFSLFLLWFVLWVVILLPARMARKRGRSAVGWVLVSLILSPLVAIVLLVLLGRSWTAR
>NC_014034.1|WP_013067016.1|1361707_1363828_-|relaxase/mobilization-nuclease-domain-containing-protein
MIGKIIALRQEIRSADHGLAARIDYVAAKATYIDTPCIPGGIDVAAAQMAATCQRHRRNPRTAHVHIVLSWPAREVPSDNQARVAAKHAMARLGAEGHEAVIGVHRDTAHIHVHTIYSRVHPITGRLVDRWQDYTRLELACREIELLQGWARDNGRFRVEIDDTGPVPAVRLVPRPAEDWALKQARRKVQADLRQGDIDQARISGHLPLHLRLPIEAMTALRQGVESAKTWAEVLARLGRFGLGYRKTPRGAVIHLRGGSEAVAVSRLIPGESHAELVARLGPLPDQHMTPTPMPPGETRLTIRGYGRGKSARIGRRPAGARAQVGALHMALLDDLQLRDQIAVINLAAPRRMVFLRDGGWVTDLGEVIRMGGPGAIRPRIEIALKMIAARGWATLDITDDTPISRALMRAAADRGITTLMPPDPTGALLRVRLRRAAAMSGPPVLPPPITAALAARAEEMHRNDLSRTARRKDRAEKMHEAEDWTERIADDLADLPSDIRKTLLRAANAALRERARSETDLRRGLTRAAPLDLFPQLRPALHSAREIAPERITVKRMTFDMVRALHEHFARRAKDDPQGQPVVFEDLLHPRPDLWLLAHRDRTGTICGYEYALWADEPVRTGMVAGSTRGLGKLPEPARKTDHDLVPTLAVAIRRLSAVPRTGTQLLSLAGPRASPDAEEILRAGLVAPRMPEAPSAREDFGREP
>NC_014034.1|WP_013067017.1|1363824_1364118_-|hypothetical-protein
MKEGATKARSEKRKATEIVACRLYPHEFRAVEAAALASGLRSSGLLARRLLLDHLARPGIDVALLRDLALKLAAENPRPAQRSILARMIEHLDEAGT
>NC_014034.1|WP_013067018.1|1364117_1364585_-|hypothetical-protein
METENPQAARHVNQIPVGDLAKIIEALKNIKPDGRQPVSAAAAIKGALKKPIKSALKRGVSYAQLVALLRELGVELTTETLKGYMRESGKPASADQTEAKMDATKAPQTSEPAVIPAVPAEPLIAVNPSGSGTPEMMMSAGAPLPQPSAHQTGTV
>NC_014034.1|WP_013067019.1|1364838_1365822_-|WYL-domain-containing-protein
MSFSKAQDLIRLAQMAAARRTGVSLDEIVEEFSISHRTAQRMTQALETTFANVTAEDGEDRKRRWRIDPGALDRLQLRPETAIEALDIAGREAVAEGRLRHRQALAGLRDGLLARLSNRDAARAEADAEAVLQALATVTRPGPRVSLAPEILDAVTEALRGPFRLRVRYKSDDAPARVLEPHGVLLGHRTYLVARDPAKGDLIRTFRLDQILSAEVLDESFAMDPAFSMERFAARSFGVWQDPAQFGPVAWRFAPHAAERAAGFRFHPSQRLEWQADGGLIVRFEAAGWLEMAWHLYQWGDAVEVLEPKGLRALVEGHRRGDFGSMP

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Crispr_ID: NC_014034_3

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_014034_3

1356300-1356476

TypeIII

Consensus_repeat	Method
GCCCAGACACCTCTCCCGCCAGTAAGCGGATTGAGACA	PILER-CR
GCCCAGACACCTCTCCCGCCAGTAAGCGGATTGAGAC	CRISPRCasFinder

2 spacers

cas2,csm3gr7,cas10,cas1,WYL

The CRISPR arrays of NC_014034_3

>merge|NC_014034|3|1356300-1356476|PILER-CR,CRISPRCasFinder
GCCCAGACACCTCTCCCGCCAGTAAGCGGATTGAGACACCCAGAACAGGTGTTTGAGCGGCCCACCCGCGCCCAGACACCTCTCCCGCCAGTAAGCGGATTGAGACGAATGACAGCAACGTACAGCATCGTTTGCCTTTGCCCAGACACCTCTCCCGCCAGTAAGCGGATTGAGACA

>NC_014034|3|3|1356300-1356476|PILER-CR
GCCCAGACACCTCTCCCGCCAGTAAGCGGATTGAGACA	CCCAGAACAGGTGTTTGAGCGGCCCACCCGC
GCCCAGACACCTCTCCCGCCAGTAAGCGGATTGAGACG	AATGACAGCAACGTACAGCATCGTTTGCCTTT
GCCCAGACACCTCTCCCGCCAGTAAGCGGATTGAGACA

>NC_014034|3|2|1356300-1356475|CRISPRCasFinder
GCCCAGACACCTCTCCCGCCAGTAAGCGGATTGAGAC	ACCCAGAACAGGTGTTTGAGCGGCCCACCCGC
GCCCAGACACCTCTCCCGCCAGTAAGCGGATTGAGAC	GAATGACAGCAACGTACAGCATCGTTTGCCTTT
GCCCAGACACCTCTCCCGCCAGTAAGCGGATTGAGAC

Protein	Signature genes	Signature genes Name	Protein_function
NC_014034.1\|WP_031321060.1\|1356525_1358133_-\|CRISPR-associated-endonuclease-Cas1	cas1	cd09634_cas1_CAS-I:CAS-II:CAS-III:CAS-V	gnl\|CDD\|376633
NC_014034.1\|WP_013067005.1\|1347481_1349284_+\|hypothetical-protein	unknown	unknown	unknown
NC_014034.1\|WP_013067019.1\|1364838_1365822_-\|WYL-domain-containing-protein	WYL	pfam13280_WYL_CAS-I:CAS-III	gnl\|CDD\|379100
NC_014034.1\|WP_148214845.1\|1344674_1345400_-\|hypothetical-protein	unknown	unknown	unknown
NC_014034.1\|WP_013067004.1\|1347027_1347285_+\|helix-turn-helix-transcriptional-regulator	unknown	unknown	gnl\|CDD\|238045
NC_014034.1\|WP_013067006.1\|1349931_1351398_+\|hypothetical-protein	cas10	cls000707_cas10_CAS-III	unknown
NC_014034.1\|WP_013067023.1\|1370620_1373236_+\|PD-(D/E)XK-nuclease-family-protein	unknown	unknown	gnl\|CDD\|378929
NC_014034.1\|WP_013067008.1\|1353037_1355665_+\|RAMP-family-CRISPR-associated-protein	csm3gr7	cd09726_csm3gr7_CAS-III-D	gnl\|CDD\|187857
NC_014034.1\|WP_013067018.1\|1364117_1364585_-\|hypothetical-protein	unknown	unknown	unknown
NC_014034.1\|WP_131618292.1\|1346290_1346500_+\|hypothetical-protein	unknown	unknown	unknown
NC_014034.1\|WP_013067015.1\|1361402_1361615_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|235095
NC_014034.1\|WP_013067003.1\|1346637_1346949_-\|hypothetical-protein	unknown	unknown	unknown
NC_014034.1\|WP_013067022.1\|1369801_1370524_+\|hypothetical-protein	unknown	unknown	unknown
NC_014034.1\|WP_013067017.1\|1363824_1364118_-\|hypothetical-protein	unknown	unknown	unknown
NC_014034.1\|WP_013067002.1\|1345539_1345941_-\|hypothetical-protein	unknown	unknown	unknown
NC_014034.1\|WP_013067021.1\|1368433_1369741_+\|McrC-family-protein	unknown	unknown	gnl\|CDD\|370821
NC_014034.1\|WP_013067009.1\|1355661_1355952_-\|CRISPR-associated-endonuclease-Cas2	cas2	pfam09827_cas2_CAS-I:CAS-II:CAS-III	gnl\|CDD\|378256
NC_014034.1\|WP_013067016.1\|1361707_1363828_-\|relaxase/mobilization-nuclease-domain-containing-protein	unknown	unknown	gnl\|CDD\|367497
NC_014034.1\|WP_013067020.1\|1366010_1368437_+\|AAA-family-ATPase	unknown	unknown	gnl\|CDD\|183088
NC_014034.1\|WP_013067007.1\|1351394_1353041_+\|hypothetical-protein	csm3gr7	cls000708_csm3gr7_CAS-III-D	gnl\|CDD\|187857

Protein	Function_ID	Function_description	E-value
NC_014034.1\|WP_031321060.1\|1356525_1358133_-\|CRISPR-associated-endonuclease-Cas1	gnl\|CDD\|376633	pfam01867, Cas_Cas1, CRISPR associated protein Cas1. Clustered regularly interspaced short palindromic repeats (CRISPRs) are a family of DNA direct repeats found in many prokaryotic genomes. This family of proteins corresponds to Cas1, a CRISPR-associated protein. Cas1 may be involved in linking DNA segments to CRISPR.	1.80138e-70
NC_014034.1\|WP_013067015.1\|1361402_1361615_+\|hypothetical-protein	gnl\|CDD\|235095	PRK02983, lysS, bifunctional lysylphosphatidylglycerol synthetase/lysine--tRNA ligase LysX.	0.00387258
NC_014034.1\|WP_013067019.1\|1364838_1365822_-\|WYL-domain-containing-protein	gnl\|CDD\|379100	pfam13280, WYL, WYL domain. WYL is a Sm-like SH3 beta-barrel fold containing domain. It is a member of the WYL-like superfamily, named for three conserved amino acids found in a subset of the superfamily. However, these residues are not strongly conserved throughout the family. Rather, the conservation pattern includes four basic residues and a position often occupied by a cysteine, which are predicted to line a ligand-binding groove typical of the Sm-like SH3 beta-barrels. A WYL domain protein (sll7009) is a negative regulator of the I-D CRISPR-Cas system in Synechocystis sp. It is predicted to be a ligand-sensing domain that could bind negatively charged ligands, such as nucleotides or nucleic acid fragments, to regulate CRISPR-Cas and other defense systems such as the abortive infection AbiG system.	7.20468e-30
NC_014034.1\|WP_013067007.1\|1351394_1353041_+\|hypothetical-protein	gnl\|CDD\|187857	cd09726, RAMP_I_III, CRISPR/Cas system-associated RAMP superfamily protein. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; RAMP superfamily proteins.	3.78656e-09
NC_014034.1\|WP_013067004.1\|1347027_1347285_+\|helix-turn-helix-transcriptional-regulator	gnl\|CDD\|238045	cd00093, HTH_XRE, Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators.	3.89223e-11
NC_014034.1\|WP_013067023.1\|1370620_1373236_+\|PD-(D/E)XK-nuclease-family-protein	gnl\|CDD\|378929	pfam12705, PDDEXK_1, PD-(D/E)XK nuclease superfamily. Members of this family belong to the PD-(D/E)XK nuclease superfamily.	3.05879e-13
NC_014034.1\|WP_013067008.1\|1353037_1355665_+\|RAMP-family-CRISPR-associated-protein	gnl\|CDD\|187857	cd09726, RAMP_I_III, CRISPR/Cas system-associated RAMP superfamily protein. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; RAMP superfamily proteins.	4.32316e-11
NC_014034.1\|WP_013067021.1\|1368433_1369741_+\|McrC-family-protein	gnl\|CDD\|370821	pfam10117, McrBC, McrBC 5-methylcytosine restriction system component. Members of this family of bacterial proteins modify the specificity of mcrB restriction by expanding the range of modified sequences restricted.	5.61014e-78
NC_014034.1\|WP_013067016.1\|1361707_1363828_-\|relaxase/mobilization-nuclease-domain-containing-protein	gnl\|CDD\|367497	pfam03432, Relaxase, Relaxase/Mobilisation nuclease domain. Relaxases/mobilisation proteins are required for the horizontal transfer of genetic information contained on plasmids that occurs during bacterial conjugation. The relaxase, in conjunction with several auxiliary proteins, forms the relaxation complex or relaxosome. Relaxases nick duplex DNA in a specific manner by catalyzing trans-esterification.	2.46547e-20
NC_014034.1\|WP_013067020.1\|1366010_1368437_+\|AAA-family-ATPase	gnl\|CDD\|183088	PRK11331, PRK11331, 5-methylcytosine-specific restriction enzyme subunit McrB; Provisional.	1.3647e-22
NC_014034.1\|WP_013067009.1\|1355661_1355952_-\|CRISPR-associated-endonuclease-Cas2	gnl\|CDD\|378256	pfam09827, CRISPR_Cas2, CRISPR associated protein Cas2. Members of this family of bacterial proteins comprise various hypothetical proteins, as well as CRISPR (clustered regularly interspaced short palindromic repeats) associated proteins, conferring resistance to infection by certain bacteriophages.	5.87522e-19

>NC_014034.1|WP_013067009.1|1355661_1355952_-|CRISPR-associated-endonuclease-Cas2
MPRAEMLMVFTYDVSQDRKRRRVARILEGAATRVQYSVFEARLSEQRAAALAQRVAAELAPGDSLRVYAIGASGETRTRTYDDAAPIEPPGNYWIV
>NC_014034.1|WP_013067008.1|1353037_1355665_+|RAMP-family-CRISPR-associated-protein
MKHLRRYRLEWTVLTPLHVGAGQSELRAHDEEDASEVALIARDHAGKPWIPGSTIKGALGATCTDVKVRLFGKPHEKGSQQARGTLTFSGARYVSKAGSSASFELAQTSVAVGTGVAAANKLYRRDFVPEGVTFTSDIDVESGDEPTVQADCAALETLLALAASSEGLNLGANKADDLGRLQITRIERAESRFGPTGWTAQTFAPHTIAASAPVRAPLFGLRMVCPGPFLSKGGQTDNETQPLMDAAGKAPRIMGTAVSGALRKRAEWLWALHLHRGGGAEMKSCKTSAGPRDLDPVQRLFGYEGRRGLLQVSPRNVSAKGSCQIPGVSLDAMTAAPRDGLLFFYHAHHGVTFDLSISTRADLDAAETNLFDLLKADLEANGLKLGMGTTKGFGWFCSDQDPILKHYSEKQTEALKLKSKEDPADHYAEAELPSNLVTIPYRLSRIDPNVIQLPEQRVSDRFSNHALLSKPMPAAASGHIDLVWHVETPVLVAAQTHDHTKPPKDVPFQKIGDTFAIPGSTIKGMLRAELERRVNARAYRIIENLLAITDDPEAERPHLDAKKQLAAFKAHRPDVNENYTPDFAEALFGFVREPESDDKSRSRHEALHLKARISCGMAWLVSEYDADKSRDELYVIAAAEPRPISKFYDHFGRKAYLVDNASAADVVARLKAAERKLDKYASPLKLLHPKQGQNLLFAQRIYLHNMTEAEIGAFLTVLTLDFTLRNRFLIGRARAFNAGKCFPAKIKLTLTPNDAGADYPARGGSKADMRMIGQSATPFLSAFGKFVNSGEDPSTARDPALARSMGFAAKEFNAAHDPLFGDYLRKRSRLDDGKIYYQQTSDDPKNRNFSASDRQKAFEANNGRLAAVLKKTWRD
>NC_014034.1|WP_013067007.1|1351394_1353041_+|hypothetical-protein
MTAPLVFDVTLSLKAPFLFPGQDPGRFGYDRVALRDLDGRPIIPQDQIKGLIRHGLTIMGETELVEGLMGKGSADARKDSGGAFEPAKGRMFLTDLRCTIEPDLRSTDYHRVQIDDESGAAKQGHLLRIEQVFAPEREVAFSGRITLFPTAKAPDAQALALLLAAALQCKRHIGAMASIGFGEVSGCSVEPALEAEEACKLPADPVGRFLWRFRVDRPYLVDAIRTDNGYIGQPTIPGGALKGLVARCAEMRGNPLDAQSLSDTVFGHATQHVAQALPLSVVCLKEKGAETCRDLAGKGALPDGVTLQIDWKAVHEAACVAGFKHCLAPPPRHVERVHTQIDATTGAAQDENLFSTTAVVPGNDVFTALVDTSALSAENARAVLSALCAPMPGLGRTDARVEPIDFVTDKAPSPVTGTVALVLQTKAWIEVDPALLRHDPLAAYAPAFKAFLPNSTLLEVHAAQELLGDYLARRFTGQSGYMPWLVTSRGSVFVLDVAPSDQAELAALQRKGLCSATRDGTALDWQSCPFVAENGYGAFLLSSVGGSR
>NC_014034.1|WP_013067006.1|1349931_1351398_+|hypothetical-protein
MFLYLEGVNLYATIYDTEDLSTIRGGSMALETLAQRAQAALGGTLRGQGASIALLEFSGPPPEEDKIRAFLSATPQCHFTLTWGTGETEAQAIKAARDRQFSQLATVVLPAIMAGVRPCAIDHTRPGTISDFDLKEQKERFLCASVADRRKIGRVGRPQLFRKRQPQPPQSFEDIAPEDAPGLKPNVRGKIAVIVADGMGGGDLAKAYGTDTAGFSTAMAAFRARLAEAIEDWASAEGLIYTDKAGVAHARVDVLMWGGDDMTFVVPASHVLGFLAALQGVLGAPFDKDKGTARFGHRIGCVIAQRKTPIRLLKKLAGSAEAALRDAVTPEMRKAGVSVVSLDVFESAPLPFASILDHRRTVYGQGYRSGADAVLLSHVAKMAAALRELDDEEGAILKMSQIYRLLDVARLSRRDLCSKAADEAIAEAMKGHFERVKGTPPDMAAWENGWTGQASRGLALLLAQVAQLQPYAQPFTDERARVLSEAVQ
>NC_014034.1|WP_013067005.1|1347481_1349284_+|hypothetical-protein
MTIDLGPIQTRAAQEIAVGGLRVWYHLPFALLDDGIDPARHGWVAEKPKGTLQQQFYFHPFVSNALWDRADGGVSALFDLYRKPAFEFRHFTADFDSTDWKEMQDGKSEQLLCRRTFRGTVRTVELRRLREPAGSGRQSGLHGFAMLVVSVDFLCAAYGEYPRDKVKDPAPFAPLTLADAQDALDLSRRIFPRWHFYGEDALPGDALTRVPCFGPAPSRPEMDEGVRKGKTQLMPWVRELVAPFTLSEPDSRHFGDERAFITSAVLLGDGSEQEAEAFTLMTRVKDSDLMRLAEVDRRGTGYSYNKPFLDALAPGYFYTRQAPDGPTGTGNSTLYITASHHFCALGAGGYMRNVILGNGIPGHHDMGHAEEYYRHMQFLCVFEFFRLLQFSQTLSELVRSQRERGAIGDKSRTAVADFGQRLMRIRDEFLDFTHLHHFSNISSQLQPREMFDRLYAAFGIPAMFAEVEKELEAATSFHEMHTNAEAREDAARLNKLVSVGVPLSLLVGAGGMNIFIGDKAPFGLHAIVPALPGQTDAAGPPDGWLQLLQLSVLVAIIAGIWALAERVYFRDKRSFWGWLAYGAAAAAFAGSEALHLWPAP
>NC_014034.1|WP_013067004.1|1347027_1347285_+|helix-turn-helix-transcriptional-regulator
MPRTIHTEGQRALCEAIAAARREKGLNQADLARELHCQQSLIARIESGERRIDVLEFIKIFRALGVSPAEALRRVGEQIPADQGI
>NC_014034.1|WP_013067003.1|1346637_1346949_-|hypothetical-protein
MQDTDDLDLEPVTFLVEAEIAARRAFDARVAREPGFSALARKRVSRYLDNPIWRGLVELHINGATSFEHGLMLRGAGLVRPARFFVRRGSEVRILSLRQISRI
>NC_014034.1|WP_131618292.1|1346290_1346500_+|hypothetical-protein
MLAMHFPSPQPMEVGLERNGEAAVASQEDWQLRSASSYGPLLGGDFFFRKQPYNFDIGTAKAEFKMEAD
>NC_014034.1|WP_013067002.1|1345539_1345941_-|hypothetical-protein
MCAKPFHANDLGNHALREAQRVATALAEAGPSATDLISAPTMHAWIGVQDTRFGGAILMGRPEGHPVCRGPVSHTSRLCGLDPDLTWARTMTRWYRLGVPADPGEVSFYALRYGIPRDLILGPDRLRDAISWV
>NC_014034.1|WP_148214845.1|1344674_1345400_-|hypothetical-protein
MRRLFSFLLFPSLPICAAPRALFLLFPLTSLSVFSLFSPLSQKSSGFSGRTVRVKGRAAPPGHGMSNSFSQISSRTGGYQHLSAVARPRPPKARSGPNRIRPILVSPPETADPDHWPRFFVGRDLGQTGAQSGMDGGQQTGRKAGGSVPPARPALRPGQGDLQRLEAALRIVAGLVIENPVYAPIFRRLEREIALEKQAQAADVIARARAVIAQNESNALIDQNEIGTSNSAACSSEAPKP
>NC_014034.1|WP_031321060.1|1356525_1358133_-|CRISPR-associated-endonuclease-Cas1
MAMAVDRISALRRMGYTWVVEADIEKAFDRIPHDPVLEALDTALDPAPGTRALIDLVGLWLAHGSGQLGTPGRGLAQGSPLSPLLSNLFFDGLDDRFDSGAARIVRFADDFVILARSEAGAEEARALAEEFVAGHGLRMVSRETRVVGFDRGFQFLGQLFVRSLVLPAPDEPDPDASAVMRELAEADAATAEAVAAGYDPGARVLYLVEPERRLSLRAESFAVLDGGGSLLLSLPPARVNRIELGPGAVVDDPVWRHALATDTTLAFLDGHGKTQGYLAPPQPAEAQLQLAQAALVLHPERRLALARVLVGARLRNQRARLAVLNRSAKATEVDRAIAALGRAIRGLAAPMPDLDTLRGHEGRAARIYWPALARLCTAHKGPFLCERPAKTPLNAAINYLTALLARDIRAALIGAGLHPGFGVLHQAQDRGDAAVYDLMEVFRATLSEGLAVSLFNRRRLREEMFEPQGDSLRLLTPGRRALITGYEEALERVIRSSQTGQRHALRRIMLEEARALARHCRSPETVPYLPQLQDY
>NC_014034.1|WP_013067015.1|1361402_1361615_+|hypothetical-protein
MDDGSGVALIGLIFSLFLLWFVLWVVILLPARMARKRGRSAVGWVLVSLILSPLVAIVLLVLLGRSWTAR
>NC_014034.1|WP_013067016.1|1361707_1363828_-|relaxase/mobilization-nuclease-domain-containing-protein
MIGKIIALRQEIRSADHGLAARIDYVAAKATYIDTPCIPGGIDVAAAQMAATCQRHRRNPRTAHVHIVLSWPAREVPSDNQARVAAKHAMARLGAEGHEAVIGVHRDTAHIHVHTIYSRVHPITGRLVDRWQDYTRLELACREIELLQGWARDNGRFRVEIDDTGPVPAVRLVPRPAEDWALKQARRKVQADLRQGDIDQARISGHLPLHLRLPIEAMTALRQGVESAKTWAEVLARLGRFGLGYRKTPRGAVIHLRGGSEAVAVSRLIPGESHAELVARLGPLPDQHMTPTPMPPGETRLTIRGYGRGKSARIGRRPAGARAQVGALHMALLDDLQLRDQIAVINLAAPRRMVFLRDGGWVTDLGEVIRMGGPGAIRPRIEIALKMIAARGWATLDITDDTPISRALMRAAADRGITTLMPPDPTGALLRVRLRRAAAMSGPPVLPPPITAALAARAEEMHRNDLSRTARRKDRAEKMHEAEDWTERIADDLADLPSDIRKTLLRAANAALRERARSETDLRRGLTRAAPLDLFPQLRPALHSAREIAPERITVKRMTFDMVRALHEHFARRAKDDPQGQPVVFEDLLHPRPDLWLLAHRDRTGTICGYEYALWADEPVRTGMVAGSTRGLGKLPEPARKTDHDLVPTLAVAIRRLSAVPRTGTQLLSLAGPRASPDAEEILRAGLVAPRMPEAPSAREDFGREP
>NC_014034.1|WP_013067017.1|1363824_1364118_-|hypothetical-protein
MKEGATKARSEKRKATEIVACRLYPHEFRAVEAAALASGLRSSGLLARRLLLDHLARPGIDVALLRDLALKLAAENPRPAQRSILARMIEHLDEAGT
>NC_014034.1|WP_013067018.1|1364117_1364585_-|hypothetical-protein
METENPQAARHVNQIPVGDLAKIIEALKNIKPDGRQPVSAAAAIKGALKKPIKSALKRGVSYAQLVALLRELGVELTTETLKGYMRESGKPASADQTEAKMDATKAPQTSEPAVIPAVPAEPLIAVNPSGSGTPEMMMSAGAPLPQPSAHQTGTV
>NC_014034.1|WP_013067019.1|1364838_1365822_-|WYL-domain-containing-protein
MSFSKAQDLIRLAQMAAARRTGVSLDEIVEEFSISHRTAQRMTQALETTFANVTAEDGEDRKRRWRIDPGALDRLQLRPETAIEALDIAGREAVAEGRLRHRQALAGLRDGLLARLSNRDAARAEADAEAVLQALATVTRPGPRVSLAPEILDAVTEALRGPFRLRVRYKSDDAPARVLEPHGVLLGHRTYLVARDPAKGDLIRTFRLDQILSAEVLDESFAMDPAFSMERFAARSFGVWQDPAQFGPVAWRFAPHAAERAAGFRFHPSQRLEWQADGGLIVRFEAAGWLEMAWHLYQWGDAVEVLEPKGLRALVEGHRRGDFGSMP
>NC_014034.1|WP_013067020.1|1366010_1368437_+|AAA-family-ATPase
MTGVTDTRRLVFYDAEGALYFPVRDGGTGKSIFKIKPKGASNRAEDAIHLEDWLDVARAMLIDGLAARCRALSGGPINYLRFGAQKLVRYELDPELAEALGIAPTGVAGEETSEVSRAAIEAAMDAFDAWRQTGAQDEIFGAFGEPRDYWVRSTRDRENRVYPTKPLVGYLRGKTDLSGGWGQRNDAASFLHNAGFIIVDAEDRPVPPPERYDHLIRDAERVRLCARNYHIEPGREQGAAEVSIRSGDLAREMGLENAFPTICDALGGAKFQTLCALPPPRFTTPNPSSTTTFTYALAADGITPTMTAPDQAPVPPTNLILYGPPGTGKTYATAWEAVKLCLGAAADPLRDDRKALMAEYKRLCEEGRIEFTTFHQSMSYEDFVEGLRPVTDEGGSGFRLTPRDGIFKEISRRASTRPDDDFDLPEIDRSRPIFKLNMIGKGWRPGYDVSIATGRIYWLFGGKLDWSDPRFEDKEALAARWRETYPEATLNHASIGGTHYFRYGAKIGDYVALTHGLDRVFAFGRITGDYEYRPDLARPEVEDSPNSRTVDWLWSDPVGVERAAFYSGAFNPAHPLCVLNDSFDHDAFEAAIFGTKGIAEPHVLIIDEINRANISKVFGELITLLEADKRLGAANEIRLRLPYSGRNFGVPANLHIIGTMNTADRSIALLDTALRRRFTFRELMPDASVLPVDCGGVNLQKLLATLNARIEYFFDREHQIGHAYFTACTTRDDVAEVMRFKIIPLLAEYFYEDWGKVAAVLGDGSGRPERFLRAVPLEPPFGLGEEDIDDKKVSWQILETFDFADCAA
>NC_014034.1|WP_013067021.1|1368433_1369741_+|McrC-family-protein
MTQFHLREWDRLPFGSGPGQIPEPLAERLVTVAKASPFAGSGEGGVLEHLRHHIRARGVVGVIAAPGVSLEILPKIDLPPGEAGETRETGDAAVRRRLIHMLAVALDLRLDLGAVTGLSWQKETLLDILIRIFADKLTEALRRGMPRRYTGLEDDLPALRGRLDVTRQFTAHAVNPARLACRFDALSEDIVLNRILKATVTHLARMTGSGALRGRLRELAFVYADIADVAPAALEWDKVVLDRTNRAWAELLAMARLFLQNRYQTTSLGRAEGTALLFEMDALFEDYIGRLIRRGVQSSGLKVTLQGGGLYCLDDAGRGLFRTKPDILIRSSGQVVQVIDTKWKRISARIEDAKQGVSQADVYQMMAYAQLYRAPRVTLLYPHHQGLATPEGVQARFTISGRPTVVETASIDVGQGAGMAARLAALVLPEAVLQG
>NC_014034.1|WP_013067022.1|1369801_1370524_+|hypothetical-protein
MQMNHLAFARSPSLRVSLKRGLARQALSEAGAVPIDMARLIALASDFRPNRKALDRLGGRIGRLPGVVRVRLCPDPLRLVVVTRAPHGVVTCHAGVEQFREESLLYVRMEVGIEAGRVMFGFTALSYCLHAIERLVERTDLPLHQPLLPVLDAEACAGFADLMAGRELTEAEATFLPAQAEGVWVVSSDWMAFDTDWGLTCLEPRGIPMHSIRTFLAPEQMRPTLWLRWRDNPTCRMAQG
>NC_014034.1|WP_013067023.1|1370620_1373236_+|PD-(D/E)XK-nuclease-family-protein
MRLSPLQTASPVTGAIRPLTTGLLRDSYLVPRAAFDPDAVLAARPGAPWAQSLAVAPVETALAVRRALEALARATETLTPAEVQPDRLPEGRARAHLGALCDLWSDLGGALPEDLHVWRHVITAEAGAALEPLPLLAPIDCPHATAAETALAQALVRQHGLAPEAVSAAWLARQPSQSACATGALGHVQANLTGLAAPIAPDTSLQIFGLRDPMEEADFAAATVQGWLDRGTIDHAAEVGLLVPEDPAYACALAEAFERVGLPLSGAPVGAILRDPAADLIAALLPVLRGPAPRTALASVVISPLMPWPAATGRAIARDLIARGYSRLWRELDGAGAALLNALRPVASLPALFARLGEIDTLITPPGSLRLQIALLRSQGGERPDWPALLALVAPLPLPGIAAPRTVEGVSVFTENDLPWRSVRRLIVLGMQGRSWPRPQPANPFFTETEIALIGTATGLHLPGRARETARRLELFRRQLCAATEAAVLLAPARDMAGARLPPSTALALIARLLGQTDPAHLVVDPRQLSPSAQPFALTPRTPDAHAGRPDLPESGDVTLGRDLLALKGAAGADPPPQSPSQLETLIVSPLAWLLAEIDARDRIWSPETLDVLVLGTVVHGVLERVFPPETPPPAPEDMPRLTEAALAEVIARKASWLAEPAWAAERASLAREALRVVQGWARFLTETGAMTLANEISLAGDHGGLLMAGRADGLLRLPDGRHLVIDHKRGTSGKRRRRMQLGWDLQVALYRAMLERPSQTSALTDAVASGSPIVTAYHTTLDGAVLTDGAGAGLARAECPATDPAREALAHLVEVTAEVGAGRLRLNTASDAVRFEKERGITAYALAGDELIAALMLPEPEDAAEEGIDD

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Crispr_ID: NC_014034_4

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_014034_4

1358648-1358971

TypeIII

Consensus_repeat	Method
GCCCAGACACCTCTCCCGCCAGTAAGCGGATTGAGAC	PILER-CR
GCCCAGACACCTCTCCCGCCAGTAAGCGGATTGAGAC	CRISPRCasFinder
GCCCAGACACCTCTCCCGCCAGTAAGCGGATTGAGAC	CRT

4 spacers

cas1,cas2,csm3gr7,cas10,WYL

The CRISPR arrays of NC_014034_4

>merge|NC_014034|4|1358648-1358971|PILER-CR,CRISPRCasFinder,CRT
GCCCAGACACCTCTCCCGCCAGTAAGCGGATTGAGACTCTTCCATCGAGCACTTGCAACCAAACACCCCGTGCCCAGACACCTCTCCCGCCAGTAAGCGGATTGAGACCTCCTTTCTCCACCCCGCGGGGTGTGCGCACGTGGCCCAGACACCTCTCCCGCCAGTAAGCGGATTGAGACGGGCGTATTCACGGCCCACCAACGCCCCCCATGCGGTGCCCAGACACCTCTCCCGCCAGTAAGCGGATTGAGACGGAAGATTTTCGGTCATCTTACGCGATCCGCATAGCCCAGACACCTCTCCCGTCCATAAGCGGGTCAGCCG

>NC_014034|4|4|1358648-1358900|PILER-CR
GCCCAGACACCTCTCCCGCCAGTAAGCGGATTGAGAC	TCTTCCATCGAGCACTTGCAACCAAACACCCCGT
GCCCAGACACCTCTCCCGCCAGTAAGCGGATTGAGAC	CTCCTTTCTCCACCCCGCGGGGTGTGCGCACGTG
GCCCAGACACCTCTCCCGCCAGTAAGCGGATTGAGAC	GGGCGTATTCACGGCCCACCAACGCCCCCCATGCGGT
GCCCAGACACCTCTCCCGCCAGTAAGCGGATTGAGAC

>NC_014034|4|3|1358648-1358971|CRISPRCasFinder
GCCCAGACACCTCTCCCGCCAGTAAGCGGATTGAGAC	TCTTCCATCGAGCACTTGCAACCAAACACCCCGT
GCCCAGACACCTCTCCCGCCAGTAAGCGGATTGAGAC	CTCCTTTCTCCACCCCGCGGGGTGTGCGCACGTG
GCCCAGACACCTCTCCCGCCAGTAAGCGGATTGAGAC	GGGCGTATTCACGGCCCACCAACGCCCCCCATGCGGT
GCCCAGACACCTCTCCCGCCAGTAAGCGGATTGAGAC	GGAAGATTTTCGGTCATCTTACGCGATCCGCATA
GCCCAGACACCTCTCCCGTCCATAAGCGGGTCAGCCG

>NC_014034|4|2|1358648-1358971|CRT
GCCCAGACACCTCTCCCGCCAGTAAGCGGATTGAGAC	TCTTCCATCGAGCACTTGCAACCAAACACCCCGT
GCCCAGACACCTCTCCCGCCAGTAAGCGGATTGAGAC	CTCCTTTCTCCACCCCGCGGGGTGTGCGCACGTG
GCCCAGACACCTCTCCCGCCAGTAAGCGGATTGAGAC	GGGCGTATTCACGGCCCACCAACGCCCCCCATGCGGT
GCCCAGACACCTCTCCCGCCAGTAAGCGGATTGAGAC	GGAAGATTTTCGGTCATCTTACGCGATCCGCATA
GCCCAGACACCTCTCCCGTCCATAAGCGGGTCAGCCG

Protein	Signature genes	Signature genes Name	Protein_function
NC_014034.1\|WP_031321060.1\|1356525_1358133_-\|CRISPR-associated-endonuclease-Cas1	cas1	cd09634_cas1_CAS-I:CAS-II:CAS-III:CAS-V	gnl\|CDD\|376633
NC_014034.1\|WP_013067005.1\|1347481_1349284_+\|hypothetical-protein	unknown	unknown	unknown
NC_014034.1\|WP_013067019.1\|1364838_1365822_-\|WYL-domain-containing-protein	WYL	pfam13280_WYL_CAS-I:CAS-III	gnl\|CDD\|379100
NC_014034.1\|WP_013067007.1\|1351394_1353041_+\|hypothetical-protein	csm3gr7	cls000708_csm3gr7_CAS-III-D	gnl\|CDD\|187857
NC_014034.1\|WP_013067004.1\|1347027_1347285_+\|helix-turn-helix-transcriptional-regulator	unknown	unknown	gnl\|CDD\|238045
NC_014034.1\|WP_013067006.1\|1349931_1351398_+\|hypothetical-protein	cas10	cls000707_cas10_CAS-III	unknown
NC_014034.1\|WP_013067023.1\|1370620_1373236_+\|PD-(D/E)XK-nuclease-family-protein	unknown	unknown	gnl\|CDD\|378929
NC_014034.1\|WP_013067008.1\|1353037_1355665_+\|RAMP-family-CRISPR-associated-protein	csm3gr7	cd09726_csm3gr7_CAS-III-D	gnl\|CDD\|187857
NC_014034.1\|WP_013067018.1\|1364117_1364585_-\|hypothetical-protein	unknown	unknown	unknown
NC_014034.1\|WP_131618292.1\|1346290_1346500_+\|hypothetical-protein	unknown	unknown	unknown
NC_014034.1\|WP_013067015.1\|1361402_1361615_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|235095
NC_014034.1\|WP_013067003.1\|1346637_1346949_-\|hypothetical-protein	unknown	unknown	unknown
NC_014034.1\|WP_013067022.1\|1369801_1370524_+\|hypothetical-protein	unknown	unknown	unknown
NC_014034.1\|WP_013067017.1\|1363824_1364118_-\|hypothetical-protein	unknown	unknown	unknown
NC_014034.1\|WP_013067024.1\|1373228_1376378_+\|UvrD-helicase-domain-containing-protein	unknown	unknown	gnl\|CDD\|224000
NC_014034.1\|WP_013067002.1\|1345539_1345941_-\|hypothetical-protein	unknown	unknown	unknown
NC_014034.1\|WP_013067021.1\|1368433_1369741_+\|McrC-family-protein	unknown	unknown	gnl\|CDD\|370821
NC_014034.1\|WP_013067016.1\|1361707_1363828_-\|relaxase/mobilization-nuclease-domain-containing-protein	unknown	unknown	gnl\|CDD\|367497
NC_014034.1\|WP_013067020.1\|1366010_1368437_+\|AAA-family-ATPase	unknown	unknown	gnl\|CDD\|183088
NC_014034.1\|WP_013067009.1\|1355661_1355952_-\|CRISPR-associated-endonuclease-Cas2	cas2	pfam09827_cas2_CAS-I:CAS-II:CAS-III	gnl\|CDD\|378256

Protein	Function_ID	Function_description	E-value
NC_014034.1\|WP_031321060.1\|1356525_1358133_-\|CRISPR-associated-endonuclease-Cas1	gnl\|CDD\|376633	pfam01867, Cas_Cas1, CRISPR associated protein Cas1. Clustered regularly interspaced short palindromic repeats (CRISPRs) are a family of DNA direct repeats found in many prokaryotic genomes. This family of proteins corresponds to Cas1, a CRISPR-associated protein. Cas1 may be involved in linking DNA segments to CRISPR.	1.80138e-70
NC_014034.1\|WP_013067015.1\|1361402_1361615_+\|hypothetical-protein	gnl\|CDD\|235095	PRK02983, lysS, bifunctional lysylphosphatidylglycerol synthetase/lysine--tRNA ligase LysX.	0.00387258
NC_014034.1\|WP_013067024.1\|1373228_1376378_+\|UvrD-helicase-domain-containing-protein	gnl\|CDD\|224000	COG1074, RecB, ATP-dependent exoDNAse (exonuclease V) beta subunit (contains helicase and exonuclease domains) [DNA replication, recombination, and repair].	1.45438e-65
NC_014034.1\|WP_013067007.1\|1351394_1353041_+\|hypothetical-protein	gnl\|CDD\|187857	cd09726, RAMP_I_III, CRISPR/Cas system-associated RAMP superfamily protein. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; RAMP superfamily proteins.	3.78656e-09
NC_014034.1\|WP_013067004.1\|1347027_1347285_+\|helix-turn-helix-transcriptional-regulator	gnl\|CDD\|238045	cd00093, HTH_XRE, Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators.	3.89223e-11
NC_014034.1\|WP_013067008.1\|1353037_1355665_+\|RAMP-family-CRISPR-associated-protein	gnl\|CDD\|187857	cd09726, RAMP_I_III, CRISPR/Cas system-associated RAMP superfamily protein. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; RAMP superfamily proteins.	4.32316e-11
NC_014034.1\|WP_013067023.1\|1370620_1373236_+\|PD-(D/E)XK-nuclease-family-protein	gnl\|CDD\|378929	pfam12705, PDDEXK_1, PD-(D/E)XK nuclease superfamily. Members of this family belong to the PD-(D/E)XK nuclease superfamily.	3.05879e-13
NC_014034.1\|WP_013067009.1\|1355661_1355952_-\|CRISPR-associated-endonuclease-Cas2	gnl\|CDD\|378256	pfam09827, CRISPR_Cas2, CRISPR associated protein Cas2. Members of this family of bacterial proteins comprise various hypothetical proteins, as well as CRISPR (clustered regularly interspaced short palindromic repeats) associated proteins, conferring resistance to infection by certain bacteriophages.	5.87522e-19
NC_014034.1\|WP_013067021.1\|1368433_1369741_+\|McrC-family-protein	gnl\|CDD\|370821	pfam10117, McrBC, McrBC 5-methylcytosine restriction system component. Members of this family of bacterial proteins modify the specificity of mcrB restriction by expanding the range of modified sequences restricted.	5.61014e-78
NC_014034.1\|WP_013067019.1\|1364838_1365822_-\|WYL-domain-containing-protein	gnl\|CDD\|379100	pfam13280, WYL, WYL domain. WYL is a Sm-like SH3 beta-barrel fold containing domain. It is a member of the WYL-like superfamily, named for three conserved amino acids found in a subset of the superfamily. However, these residues are not strongly conserved throughout the family. Rather, the conservation pattern includes four basic residues and a position often occupied by a cysteine, which are predicted to line a ligand-binding groove typical of the Sm-like SH3 beta-barrels. A WYL domain protein (sll7009) is a negative regulator of the I-D CRISPR-Cas system in Synechocystis sp. It is predicted to be a ligand-sensing domain that could bind negatively charged ligands, such as nucleotides or nucleic acid fragments, to regulate CRISPR-Cas and other defense systems such as the abortive infection AbiG system.	7.20468e-30
NC_014034.1\|WP_013067020.1\|1366010_1368437_+\|AAA-family-ATPase	gnl\|CDD\|183088	PRK11331, PRK11331, 5-methylcytosine-specific restriction enzyme subunit McrB; Provisional.	1.3647e-22
NC_014034.1\|WP_013067016.1\|1361707_1363828_-\|relaxase/mobilization-nuclease-domain-containing-protein	gnl\|CDD\|367497	pfam03432, Relaxase, Relaxase/Mobilisation nuclease domain. Relaxases/mobilisation proteins are required for the horizontal transfer of genetic information contained on plasmids that occurs during bacterial conjugation. The relaxase, in conjunction with several auxiliary proteins, forms the relaxation complex or relaxosome. Relaxases nick duplex DNA in a specific manner by catalyzing trans-esterification.	2.46547e-20

>NC_014034.1|WP_031321060.1|1356525_1358133_-|CRISPR-associated-endonuclease-Cas1
MAMAVDRISALRRMGYTWVVEADIEKAFDRIPHDPVLEALDTALDPAPGTRALIDLVGLWLAHGSGQLGTPGRGLAQGSPLSPLLSNLFFDGLDDRFDSGAARIVRFADDFVILARSEAGAEEARALAEEFVAGHGLRMVSRETRVVGFDRGFQFLGQLFVRSLVLPAPDEPDPDASAVMRELAEADAATAEAVAAGYDPGARVLYLVEPERRLSLRAESFAVLDGGGSLLLSLPPARVNRIELGPGAVVDDPVWRHALATDTTLAFLDGHGKTQGYLAPPQPAEAQLQLAQAALVLHPERRLALARVLVGARLRNQRARLAVLNRSAKATEVDRAIAALGRAIRGLAAPMPDLDTLRGHEGRAARIYWPALARLCTAHKGPFLCERPAKTPLNAAINYLTALLARDIRAALIGAGLHPGFGVLHQAQDRGDAAVYDLMEVFRATLSEGLAVSLFNRRRLREEMFEPQGDSLRLLTPGRRALITGYEEALERVIRSSQTGQRHALRRIMLEEARALARHCRSPETVPYLPQLQDY
>NC_014034.1|WP_013067009.1|1355661_1355952_-|CRISPR-associated-endonuclease-Cas2
MPRAEMLMVFTYDVSQDRKRRRVARILEGAATRVQYSVFEARLSEQRAAALAQRVAAELAPGDSLRVYAIGASGETRTRTYDDAAPIEPPGNYWIV
>NC_014034.1|WP_013067008.1|1353037_1355665_+|RAMP-family-CRISPR-associated-protein
MKHLRRYRLEWTVLTPLHVGAGQSELRAHDEEDASEVALIARDHAGKPWIPGSTIKGALGATCTDVKVRLFGKPHEKGSQQARGTLTFSGARYVSKAGSSASFELAQTSVAVGTGVAAANKLYRRDFVPEGVTFTSDIDVESGDEPTVQADCAALETLLALAASSEGLNLGANKADDLGRLQITRIERAESRFGPTGWTAQTFAPHTIAASAPVRAPLFGLRMVCPGPFLSKGGQTDNETQPLMDAAGKAPRIMGTAVSGALRKRAEWLWALHLHRGGGAEMKSCKTSAGPRDLDPVQRLFGYEGRRGLLQVSPRNVSAKGSCQIPGVSLDAMTAAPRDGLLFFYHAHHGVTFDLSISTRADLDAAETNLFDLLKADLEANGLKLGMGTTKGFGWFCSDQDPILKHYSEKQTEALKLKSKEDPADHYAEAELPSNLVTIPYRLSRIDPNVIQLPEQRVSDRFSNHALLSKPMPAAASGHIDLVWHVETPVLVAAQTHDHTKPPKDVPFQKIGDTFAIPGSTIKGMLRAELERRVNARAYRIIENLLAITDDPEAERPHLDAKKQLAAFKAHRPDVNENYTPDFAEALFGFVREPESDDKSRSRHEALHLKARISCGMAWLVSEYDADKSRDELYVIAAAEPRPISKFYDHFGRKAYLVDNASAADVVARLKAAERKLDKYASPLKLLHPKQGQNLLFAQRIYLHNMTEAEIGAFLTVLTLDFTLRNRFLIGRARAFNAGKCFPAKIKLTLTPNDAGADYPARGGSKADMRMIGQSATPFLSAFGKFVNSGEDPSTARDPALARSMGFAAKEFNAAHDPLFGDYLRKRSRLDDGKIYYQQTSDDPKNRNFSASDRQKAFEANNGRLAAVLKKTWRD
>NC_014034.1|WP_013067007.1|1351394_1353041_+|hypothetical-protein
MTAPLVFDVTLSLKAPFLFPGQDPGRFGYDRVALRDLDGRPIIPQDQIKGLIRHGLTIMGETELVEGLMGKGSADARKDSGGAFEPAKGRMFLTDLRCTIEPDLRSTDYHRVQIDDESGAAKQGHLLRIEQVFAPEREVAFSGRITLFPTAKAPDAQALALLLAAALQCKRHIGAMASIGFGEVSGCSVEPALEAEEACKLPADPVGRFLWRFRVDRPYLVDAIRTDNGYIGQPTIPGGALKGLVARCAEMRGNPLDAQSLSDTVFGHATQHVAQALPLSVVCLKEKGAETCRDLAGKGALPDGVTLQIDWKAVHEAACVAGFKHCLAPPPRHVERVHTQIDATTGAAQDENLFSTTAVVPGNDVFTALVDTSALSAENARAVLSALCAPMPGLGRTDARVEPIDFVTDKAPSPVTGTVALVLQTKAWIEVDPALLRHDPLAAYAPAFKAFLPNSTLLEVHAAQELLGDYLARRFTGQSGYMPWLVTSRGSVFVLDVAPSDQAELAALQRKGLCSATRDGTALDWQSCPFVAENGYGAFLLSSVGGSR
>NC_014034.1|WP_013067006.1|1349931_1351398_+|hypothetical-protein
MFLYLEGVNLYATIYDTEDLSTIRGGSMALETLAQRAQAALGGTLRGQGASIALLEFSGPPPEEDKIRAFLSATPQCHFTLTWGTGETEAQAIKAARDRQFSQLATVVLPAIMAGVRPCAIDHTRPGTISDFDLKEQKERFLCASVADRRKIGRVGRPQLFRKRQPQPPQSFEDIAPEDAPGLKPNVRGKIAVIVADGMGGGDLAKAYGTDTAGFSTAMAAFRARLAEAIEDWASAEGLIYTDKAGVAHARVDVLMWGGDDMTFVVPASHVLGFLAALQGVLGAPFDKDKGTARFGHRIGCVIAQRKTPIRLLKKLAGSAEAALRDAVTPEMRKAGVSVVSLDVFESAPLPFASILDHRRTVYGQGYRSGADAVLLSHVAKMAAALRELDDEEGAILKMSQIYRLLDVARLSRRDLCSKAADEAIAEAMKGHFERVKGTPPDMAAWENGWTGQASRGLALLLAQVAQLQPYAQPFTDERARVLSEAVQ
>NC_014034.1|WP_013067005.1|1347481_1349284_+|hypothetical-protein
MTIDLGPIQTRAAQEIAVGGLRVWYHLPFALLDDGIDPARHGWVAEKPKGTLQQQFYFHPFVSNALWDRADGGVSALFDLYRKPAFEFRHFTADFDSTDWKEMQDGKSEQLLCRRTFRGTVRTVELRRLREPAGSGRQSGLHGFAMLVVSVDFLCAAYGEYPRDKVKDPAPFAPLTLADAQDALDLSRRIFPRWHFYGEDALPGDALTRVPCFGPAPSRPEMDEGVRKGKTQLMPWVRELVAPFTLSEPDSRHFGDERAFITSAVLLGDGSEQEAEAFTLMTRVKDSDLMRLAEVDRRGTGYSYNKPFLDALAPGYFYTRQAPDGPTGTGNSTLYITASHHFCALGAGGYMRNVILGNGIPGHHDMGHAEEYYRHMQFLCVFEFFRLLQFSQTLSELVRSQRERGAIGDKSRTAVADFGQRLMRIRDEFLDFTHLHHFSNISSQLQPREMFDRLYAAFGIPAMFAEVEKELEAATSFHEMHTNAEAREDAARLNKLVSVGVPLSLLVGAGGMNIFIGDKAPFGLHAIVPALPGQTDAAGPPDGWLQLLQLSVLVAIIAGIWALAERVYFRDKRSFWGWLAYGAAAAAFAGSEALHLWPAP
>NC_014034.1|WP_013067004.1|1347027_1347285_+|helix-turn-helix-transcriptional-regulator
MPRTIHTEGQRALCEAIAAARREKGLNQADLARELHCQQSLIARIESGERRIDVLEFIKIFRALGVSPAEALRRVGEQIPADQGI
>NC_014034.1|WP_013067003.1|1346637_1346949_-|hypothetical-protein
MQDTDDLDLEPVTFLVEAEIAARRAFDARVAREPGFSALARKRVSRYLDNPIWRGLVELHINGATSFEHGLMLRGAGLVRPARFFVRRGSEVRILSLRQISRI
>NC_014034.1|WP_131618292.1|1346290_1346500_+|hypothetical-protein
MLAMHFPSPQPMEVGLERNGEAAVASQEDWQLRSASSYGPLLGGDFFFRKQPYNFDIGTAKAEFKMEAD
>NC_014034.1|WP_013067002.1|1345539_1345941_-|hypothetical-protein
MCAKPFHANDLGNHALREAQRVATALAEAGPSATDLISAPTMHAWIGVQDTRFGGAILMGRPEGHPVCRGPVSHTSRLCGLDPDLTWARTMTRWYRLGVPADPGEVSFYALRYGIPRDLILGPDRLRDAISWV
>NC_014034.1|WP_013067015.1|1361402_1361615_+|hypothetical-protein
MDDGSGVALIGLIFSLFLLWFVLWVVILLPARMARKRGRSAVGWVLVSLILSPLVAIVLLVLLGRSWTAR
>NC_014034.1|WP_013067016.1|1361707_1363828_-|relaxase/mobilization-nuclease-domain-containing-protein
MIGKIIALRQEIRSADHGLAARIDYVAAKATYIDTPCIPGGIDVAAAQMAATCQRHRRNPRTAHVHIVLSWPAREVPSDNQARVAAKHAMARLGAEGHEAVIGVHRDTAHIHVHTIYSRVHPITGRLVDRWQDYTRLELACREIELLQGWARDNGRFRVEIDDTGPVPAVRLVPRPAEDWALKQARRKVQADLRQGDIDQARISGHLPLHLRLPIEAMTALRQGVESAKTWAEVLARLGRFGLGYRKTPRGAVIHLRGGSEAVAVSRLIPGESHAELVARLGPLPDQHMTPTPMPPGETRLTIRGYGRGKSARIGRRPAGARAQVGALHMALLDDLQLRDQIAVINLAAPRRMVFLRDGGWVTDLGEVIRMGGPGAIRPRIEIALKMIAARGWATLDITDDTPISRALMRAAADRGITTLMPPDPTGALLRVRLRRAAAMSGPPVLPPPITAALAARAEEMHRNDLSRTARRKDRAEKMHEAEDWTERIADDLADLPSDIRKTLLRAANAALRERARSETDLRRGLTRAAPLDLFPQLRPALHSAREIAPERITVKRMTFDMVRALHEHFARRAKDDPQGQPVVFEDLLHPRPDLWLLAHRDRTGTICGYEYALWADEPVRTGMVAGSTRGLGKLPEPARKTDHDLVPTLAVAIRRLSAVPRTGTQLLSLAGPRASPDAEEILRAGLVAPRMPEAPSAREDFGREP
>NC_014034.1|WP_013067017.1|1363824_1364118_-|hypothetical-protein
MKEGATKARSEKRKATEIVACRLYPHEFRAVEAAALASGLRSSGLLARRLLLDHLARPGIDVALLRDLALKLAAENPRPAQRSILARMIEHLDEAGT
>NC_014034.1|WP_013067018.1|1364117_1364585_-|hypothetical-protein
METENPQAARHVNQIPVGDLAKIIEALKNIKPDGRQPVSAAAAIKGALKKPIKSALKRGVSYAQLVALLRELGVELTTETLKGYMRESGKPASADQTEAKMDATKAPQTSEPAVIPAVPAEPLIAVNPSGSGTPEMMMSAGAPLPQPSAHQTGTV
>NC_014034.1|WP_013067019.1|1364838_1365822_-|WYL-domain-containing-protein
MSFSKAQDLIRLAQMAAARRTGVSLDEIVEEFSISHRTAQRMTQALETTFANVTAEDGEDRKRRWRIDPGALDRLQLRPETAIEALDIAGREAVAEGRLRHRQALAGLRDGLLARLSNRDAARAEADAEAVLQALATVTRPGPRVSLAPEILDAVTEALRGPFRLRVRYKSDDAPARVLEPHGVLLGHRTYLVARDPAKGDLIRTFRLDQILSAEVLDESFAMDPAFSMERFAARSFGVWQDPAQFGPVAWRFAPHAAERAAGFRFHPSQRLEWQADGGLIVRFEAAGWLEMAWHLYQWGDAVEVLEPKGLRALVEGHRRGDFGSMP
>NC_014034.1|WP_013067020.1|1366010_1368437_+|AAA-family-ATPase
MTGVTDTRRLVFYDAEGALYFPVRDGGTGKSIFKIKPKGASNRAEDAIHLEDWLDVARAMLIDGLAARCRALSGGPINYLRFGAQKLVRYELDPELAEALGIAPTGVAGEETSEVSRAAIEAAMDAFDAWRQTGAQDEIFGAFGEPRDYWVRSTRDRENRVYPTKPLVGYLRGKTDLSGGWGQRNDAASFLHNAGFIIVDAEDRPVPPPERYDHLIRDAERVRLCARNYHIEPGREQGAAEVSIRSGDLAREMGLENAFPTICDALGGAKFQTLCALPPPRFTTPNPSSTTTFTYALAADGITPTMTAPDQAPVPPTNLILYGPPGTGKTYATAWEAVKLCLGAAADPLRDDRKALMAEYKRLCEEGRIEFTTFHQSMSYEDFVEGLRPVTDEGGSGFRLTPRDGIFKEISRRASTRPDDDFDLPEIDRSRPIFKLNMIGKGWRPGYDVSIATGRIYWLFGGKLDWSDPRFEDKEALAARWRETYPEATLNHASIGGTHYFRYGAKIGDYVALTHGLDRVFAFGRITGDYEYRPDLARPEVEDSPNSRTVDWLWSDPVGVERAAFYSGAFNPAHPLCVLNDSFDHDAFEAAIFGTKGIAEPHVLIIDEINRANISKVFGELITLLEADKRLGAANEIRLRLPYSGRNFGVPANLHIIGTMNTADRSIALLDTALRRRFTFRELMPDASVLPVDCGGVNLQKLLATLNARIEYFFDREHQIGHAYFTACTTRDDVAEVMRFKIIPLLAEYFYEDWGKVAAVLGDGSGRPERFLRAVPLEPPFGLGEEDIDDKKVSWQILETFDFADCAA
>NC_014034.1|WP_013067021.1|1368433_1369741_+|McrC-family-protein
MTQFHLREWDRLPFGSGPGQIPEPLAERLVTVAKASPFAGSGEGGVLEHLRHHIRARGVVGVIAAPGVSLEILPKIDLPPGEAGETRETGDAAVRRRLIHMLAVALDLRLDLGAVTGLSWQKETLLDILIRIFADKLTEALRRGMPRRYTGLEDDLPALRGRLDVTRQFTAHAVNPARLACRFDALSEDIVLNRILKATVTHLARMTGSGALRGRLRELAFVYADIADVAPAALEWDKVVLDRTNRAWAELLAMARLFLQNRYQTTSLGRAEGTALLFEMDALFEDYIGRLIRRGVQSSGLKVTLQGGGLYCLDDAGRGLFRTKPDILIRSSGQVVQVIDTKWKRISARIEDAKQGVSQADVYQMMAYAQLYRAPRVTLLYPHHQGLATPEGVQARFTISGRPTVVETASIDVGQGAGMAARLAALVLPEAVLQG
>NC_014034.1|WP_013067022.1|1369801_1370524_+|hypothetical-protein
MQMNHLAFARSPSLRVSLKRGLARQALSEAGAVPIDMARLIALASDFRPNRKALDRLGGRIGRLPGVVRVRLCPDPLRLVVVTRAPHGVVTCHAGVEQFREESLLYVRMEVGIEAGRVMFGFTALSYCLHAIERLVERTDLPLHQPLLPVLDAEACAGFADLMAGRELTEAEATFLPAQAEGVWVVSSDWMAFDTDWGLTCLEPRGIPMHSIRTFLAPEQMRPTLWLRWRDNPTCRMAQG
>NC_014034.1|WP_013067023.1|1370620_1373236_+|PD-(D/E)XK-nuclease-family-protein
MRLSPLQTASPVTGAIRPLTTGLLRDSYLVPRAAFDPDAVLAARPGAPWAQSLAVAPVETALAVRRALEALARATETLTPAEVQPDRLPEGRARAHLGALCDLWSDLGGALPEDLHVWRHVITAEAGAALEPLPLLAPIDCPHATAAETALAQALVRQHGLAPEAVSAAWLARQPSQSACATGALGHVQANLTGLAAPIAPDTSLQIFGLRDPMEEADFAAATVQGWLDRGTIDHAAEVGLLVPEDPAYACALAEAFERVGLPLSGAPVGAILRDPAADLIAALLPVLRGPAPRTALASVVISPLMPWPAATGRAIARDLIARGYSRLWRELDGAGAALLNALRPVASLPALFARLGEIDTLITPPGSLRLQIALLRSQGGERPDWPALLALVAPLPLPGIAAPRTVEGVSVFTENDLPWRSVRRLIVLGMQGRSWPRPQPANPFFTETEIALIGTATGLHLPGRARETARRLELFRRQLCAATEAAVLLAPARDMAGARLPPSTALALIARLLGQTDPAHLVVDPRQLSPSAQPFALTPRTPDAHAGRPDLPESGDVTLGRDLLALKGAAGADPPPQSPSQLETLIVSPLAWLLAEIDARDRIWSPETLDVLVLGTVVHGVLERVFPPETPPPAPEDMPRLTEAALAEVIARKASWLAEPAWAAERASLAREALRVVQGWARFLTETGAMTLANEISLAGDHGGLLMAGRADGLLRLPDGRHLVIDHKRGTSGKRRRRMQLGWDLQVALYRAMLERPSQTSALTDAVASGSPIVTAYHTTLDGAVLTDGAGAGLARAECPATDPAREALAHLVEVTAEVGAGRLRLNTASDAVRFEKERGITAYALAGDELIAALMLPEPEDAAEEGIDD
>NC_014034.1|WP_013067024.1|1373228_1376378_+|UvrD-helicase-domain-containing-protein
MTDLTLVPAGAGAGKTTRIQRTVAGWVSAGLVAPGRILAVTFTEAAAAELKARIRAQLIAQDQVAEALELERAYIGTIHGLGQRLLTEHAFGAGRAPVSRLLTEAERDLLIRLQMGGCGPLQEVMGDLARFGYAWNRQTGASAEDQFRADVLRTIDLLRGLGARGASPDVLAGALAALDAGYGPRAAEGAPLTDALRRAAQALLARFPEGIADQATSDAAIKAFRDDHARLRRAAETDALNSDWGLWQKLRTLRQSKRGAPTPEGYDALAQGVMEAAEALLIHPGPLTDARAHLAALIHGAQALMAGYDAAKRAGGLIDFADMITETEALLAARPEILAATLGEIDCVVIDEFQDTNPVQFSLLWRLARGAARALIVGDTKQAIMRFQGADPRLSGALHAACPEAVDPLDHNYRSDPRIMRFVNALGPVLFPEGYDALAPHRAETGVPALEALVLPKAKKDVSAPCIAAHVAALLHEGAQVSDRATGQLRAAQPSDVAVLCYTAAKAASVAKALRAEGFAVRIQADGWRAAPIIRVVRAALALVADPEDSHAALRYLTLGPARLPLQAALTLAIDGALATHAGLAPLLSLAEDAPHLTVAALLSKIIPAAGLRDWAATLEAPAQALADLARFEAEAQAFDALAADLKAAAGFHGASAQVFLGWLAAQTGRDVDRHPDAAGWSAPGIEICTWHAAKGREWPITVVAGLDYKFIARPNTLRAEFDGFDDLDAVLDHAGLGWLPDFAAPEKQAAFAEALVADDERDAARELYVALTRARDRLILALPTAPSKEKPRPERMVDLLRARSGLATTTDGTGLTICGESFPARVVMAADPDAGAEAAPDPQPVPRFGLARPHPGTPLRLWRTTPSGLIAPADAARPNLRLIALGAAVRRQRDGFDLATERGSAWHLAFRVAAERPERLAEVGPATGLAPDTVAQIAAQAAALRHWLLAEGFDRLHFELPLQEIAADGSEINAIVDLLAEGPQGLLIVDHKSGACPYPEARFAGYASQLQAYAGLAERAFAKPVRGLAVNWMNEGEVSVLDLQEVPA

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Crispr_ID: NC_014034_5

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_014034_5

1395365-1398068

TypeI

I-C

Consensus_repeat	Method
GTCGCTCCCCCCGCGGGGGCGTGGATCGAAAC	PILER-CR
GTCGCTCCCCCCGCGGGGGCGTGGATCGAAAC	CRISPRCasFinder
GTCGCTCCCCCCGCGGGGGCGTGGATCGAAAC	CRT

40 spacers

cas2,cas1,cas4,cas7,cas8c,cas5,cas3,WYL

The CRISPR arrays of NC_014034_5

>merge|NC_014034|5|1395365-1398068|PILER-CR,CRISPRCasFinder,CRT
GTCGCTCCCCCCGCGGGGGCGTGGATCGAAACTGCACCCGCTGGCCCTGCCGGTGATCGGTGATCAGCGGTCGCTCCCCCCGCGGGGGCGTGGATCGAAACATCGCCGCTTTGGCGGTCGACAGGCTGGTAACGTGTCGCTCCCCCCGCGGGGGCGTGGATCGAAACATCTCGGTGCCGTCGCTCGTCCAGCCGGCCTGCTCGTCGCTCCCCCCGCGGGGGCGTGGATCGAAACCACCTTGCGGATTGTCACTTTCGCGGGGCGAAGCGTCGCTCCCCCCGCGGGGGCGTGGATCGAAACATCTGCATGTAGTCGGCGGGCAGTTCGAGCCGCAGTCGCTCCCCCCGCGGGGGCGTGGATCGAAACTGGTATGGATCTGGCGCAAACGGAAAGTCTGTCGTCGCTCCCCCCGCGGGGGCGTGGATCGAAACCTGCGGCGTGAGTTGCCAGTGATAGACGCCGTGGACGTCGCTCCCCCCGCGGGGGCGTGGATCGAAACTGCGCCGCCTATCGCATCCGGTCGAGCGCCGCGCAGTCGCTCCCCCCGCGGGGGCGTGGATCGAAACGATGCGTTCATGGCCTACGTCGGGCAGTGGACTGGTCGCTCCCCCCGCGGGGGCGTGGATCGAAACTCGCCCTCGATCCGCGCTTGCCTCACGCCTGCCGCGTCGCTCCCCCCGCGGGGGCGTGGATCGAAACAGGCGCATCTGATGTATATGCCCGGTGAGACGGCTGTCGCTCCCCCCGCGGGGGCGTGGATCGAAACTTTTCGTCATCTGGCAGGCTCGCGCCGCCACGCTGCGTCGCTCCCCCCGCGGGGGCGTGGATCGAAACCCGGCGAAAAACGGCCATGCCTCCGGGTGTCTGGCTGTCGCTCCCCCCGCGGGGGCGTGGATCGAAACAGCAGGTCAGCCGCGGCCCCGGTGAACTTCTGTTCGTCGCTCCCCCCGCGGGGGCGTGGATCGAAACAAGCAGTGGGGTGAGTGGGCTGACCAGACAAACGCTGTCGCTCCCCCCGCGGGGGCGTGGATCGAAACCGCGCCCTGCGGGTGATGGCGACGGGCACCACGGCGGTCGCTCCCCCCGCGGGGGCGTGGATCGAAACGGACCTGAAATTCCGCGGGAAACGCGGCGGCGAGCACGTCGCTCCCCCCGCGGGGGCGTGGATCGAAACTGCTTTCGTGGGACTGGCCAGCCGCCCGCGCCAAGTCGCTCCCCCCGCGGGGGCGTGGATCGAAACGATTTCGTCGCTTACGACGCCTATCTGATTTCGGGTCGCTCCCCCCGCGGGGGCGTGGATCGAAACCATGCGGCGATAACTCGCTCTTGCGATCCGTCATCGTCGCTCCCCCCGCGGGGGCGTGGATCGAAACCCTGTCCCTCATATGCTGCCACGATGCCCTTGAGTCGCTCCCCCCGCGGGGGCGTGGATCGAAACCGTGTGGATGATCATGCAGCGCGGACGGCTTGGGTCGCTCCCCCCGCGGGGGCGTGGATCGAAACCGGTCCAGAGATAGACCGCGCGGACCTCCTCAGACGTCGCTCCCCCCGCGGGGGCGTGGATCGAAACAGCCTGCGCGGCCGCATCGGCTTCCGCCTGCGTGGTCGCTCCCCCCGCGGGGGCGTGGATCGAAACATCAGCTCGTCGTTGGTCAGCCGGACGATGTCCGTCGCTCCCCCCGCGGGGGCGTGGATCGAAACTGCCGTCTTGAGTGATGGGGCGCGAGCACATGTCGTCGCTCCCCCCGCGGGGGCGTGGATCGAAACGTCCAGCTCGCGCCACATGTCTTCGACCGTGCGCCGTCGCTCCCCCCGCGGGGGCGTGGATCGAAACGTGTCTGCCACGACGCCCTGCACCAGATCCGCGCCGTCGCTCCCCCCGCGGGGGCGTGGATCGAAACACCGCGCACGCGCGAACGGCGTCAGCCCCGCGAACGTCGCTCCCCCCGCGGGAGCGTGGATCGAAACGGCTTTACAGCCTTCGCGCCCCACGCCAGACGGACGTCGCTCCCCCCGCGGGGGCGTGGATCGAAACTCTTCAATGGATATGGCAAAACCGTCCGCGACATGTCGCTCCCCCCGCGGGGGCGTGGATCGAAACACCGTCATCACCACGCAACCGCCCTGCACCACCGGTCGCTCCCCCCGCGGGGGCGTGGATCGAAACAACCCGATCATGGCCCGCCTCAGCGCCGCGCTGACGTCGCTCCCCCCGCGGGGGCGTGGATCGAAACATCCGCGGATCGGCGTGACCCGCCCCGCCCATCGGTCGCTCCCCCCGCGGGGGCGTGGATCGAAACTACAGAGTTCCGGTCTTGTTCTGTTCCGGTAACAGGTCGCTCCCCCCGCGGGCGCGTGGATCGAAACTTGTCTGACGCGCTCATCAGCACGTCAAGATTCAGTCGCTCCCCCCGCGGGGGCGTGGATCGAAACGGTGTCCAGCGTCACATGCAGCGGCGTCGCATCGCCATGTCGCTCCCCCCGCGGGGGCGTGGATCGAAACCCGGCACCTCAGCCCCGCCCGCTGTCTCACCAACAGTCGCTCCCCCCGCGGGGGCGTGGATCGAAACTCTATGGGAGGCTAGGGAGGCTACGCACCTTCAAAAGTCGCTCCCCCCGCGGGGGCGTGGATCGAAACCGCCGCGCAAAAAGCCCGCCAAGAAGCGGAGCAAGTCGCTCCCCCCGCGGGGGCGTGGATCGTAAG

>NC_014034|5|5|1395365-1398002|PILER-CR
GTCGCTCCCCCCGCGGGGGCGTGGATCGAAAC	TGCACCCGCTGGCCCTGCCGGTGATCGGTGATCAGCG
GTCGCTCCCCCCGCGGGGGCGTGGATCGAAAC	ATCGCCGCTTTGGCGGTCGACAGGCTGGTAACGT
GTCGCTCCCCCCGCGGGGGCGTGGATCGAAAC	ATCTCGGTGCCGTCGCTCGTCCAGCCGGCCTGCTC
GTCGCTCCCCCCGCGGGGGCGTGGATCGAAAC	CACCTTGCGGATTGTCACTTTCGCGGGGCGAAGC
GTCGCTCCCCCCGCGGGGGCGTGGATCGAAAC	ATCTGCATGTAGTCGGCGGGCAGTTCGAGCCGCA
GTCGCTCCCCCCGCGGGGGCGTGGATCGAAAC	TGGTATGGATCTGGCGCAAACGGAAAGTCTGTC
GTCGCTCCCCCCGCGGGGGCGTGGATCGAAAC	CTGCGGCGTGAGTTGCCAGTGATAGACGCCGTGGAC
GTCGCTCCCCCCGCGGGGGCGTGGATCGAAAC	TGCGCCGCCTATCGCATCCGGTCGAGCGCCGCGCA
GTCGCTCCCCCCGCGGGGGCGTGGATCGAAAC	GATGCGTTCATGGCCTACGTCGGGCAGTGGACTG
GTCGCTCCCCCCGCGGGGGCGTGGATCGAAAC	TCGCCCTCGATCCGCGCTTGCCTCACGCCTGCCGC
GTCGCTCCCCCCGCGGGGGCGTGGATCGAAAC	AGGCGCATCTGATGTATATGCCCGGTGAGACGGCT
GTCGCTCCCCCCGCGGGGGCGTGGATCGAAAC	TTTTCGTCATCTGGCAGGCTCGCGCCGCCACGCTGC
GTCGCTCCCCCCGCGGGGGCGTGGATCGAAAC	CCGGCGAAAAACGGCCATGCCTCCGGGTGTCTGGCT
GTCGCTCCCCCCGCGGGGGCGTGGATCGAAAC	AGCAGGTCAGCCGCGGCCCCGGTGAACTTCTGTTC
GTCGCTCCCCCCGCGGGGGCGTGGATCGAAAC	AAGCAGTGGGGTGAGTGGGCTGACCAGACAAACGCT
GTCGCTCCCCCCGCGGGGGCGTGGATCGAAAC	CGCGCCCTGCGGGTGATGGCGACGGGCACCACGGCG
GTCGCTCCCCCCGCGGGGGCGTGGATCGAAAC	GGACCTGAAATTCCGCGGGAAACGCGGCGGCGAGCAC
GTCGCTCCCCCCGCGGGGGCGTGGATCGAAAC	TGCTTTCGTGGGACTGGCCAGCCGCCCGCGCCAA
GTCGCTCCCCCCGCGGGGGCGTGGATCGAAAC	GATTTCGTCGCTTACGACGCCTATCTGATTTCGG
GTCGCTCCCCCCGCGGGGGCGTGGATCGAAAC	CATGCGGCGATAACTCGCTCTTGCGATCCGTCATC
GTCGCTCCCCCCGCGGGGGCGTGGATCGAAAC	CCTGTCCCTCATATGCTGCCACGATGCCCTTGA
GTCGCTCCCCCCGCGGGGGCGTGGATCGAAAC	CGTGTGGATGATCATGCAGCGCGGACGGCTTGG
GTCGCTCCCCCCGCGGGGGCGTGGATCGAAAC	CGGTCCAGAGATAGACCGCGCGGACCTCCTCAGAC
GTCGCTCCCCCCGCGGGGGCGTGGATCGAAAC	AGCCTGCGCGGCCGCATCGGCTTCCGCCTGCGTG
GTCGCTCCCCCCGCGGGGGCGTGGATCGAAAC	ATCAGCTCGTCGTTGGTCAGCCGGACGATGTCC
GTCGCTCCCCCCGCGGGGGCGTGGATCGAAAC	TGCCGTCTTGAGTGATGGGGCGCGAGCACATGTC
GTCGCTCCCCCCGCGGGGGCGTGGATCGAAAC	GTCCAGCTCGCGCCACATGTCTTCGACCGTGCGCC
GTCGCTCCCCCCGCGGGGGCGTGGATCGAAAC	GTGTCTGCCACGACGCCCTGCACCAGATCCGCGCC
GTCGCTCCCCCCGCGGGGGCGTGGATCGAAAC	ACCGCGCACGCGCGAACGGCGTCAGCCCCGCGAAC
GTCGCTCCCCCCGCGGGAGCGTGGATCGAAAC	GGCTTTACAGCCTTCGCGCCCCACGCCAGACGGAC
GTCGCTCCCCCCGCGGGGGCGTGGATCGAAAC	TCTTCAATGGATATGGCAAAACCGTCCGCGACAT
GTCGCTCCCCCCGCGGGGGCGTGGATCGAAAC	ACCGTCATCACCACGCAACCGCCCTGCACCACCG
GTCGCTCCCCCCGCGGGGGCGTGGATCGAAAC	AACCCGATCATGGCCCGCCTCAGCGCCGCGCTGAC
GTCGCTCCCCCCGCGGGGGCGTGGATCGAAAC	ATCCGCGGATCGGCGTGACCCGCCCCGCCCATCG
GTCGCTCCCCCCGCGGGGGCGTGGATCGAAAC	TACAGAGTTCCGGTCTTGTTCTGTTCCGGTAACAG
GTCGCTCCCCCCGCGGGCGCGTGGATCGAAAC	TTGTCTGACGCGCTCATCAGCACGTCAAGATTCA
GTCGCTCCCCCCGCGGGGGCGTGGATCGAAAC	GGTGTCCAGCGTCACATGCAGCGGCGTCGCATCGCCAT
GTCGCTCCCCCCGCGGGGGCGTGGATCGAAAC	CCGGCACCTCAGCCCCGCCCGCTGTCTCACCAACA
GTCGCTCCCCCCGCGGGGGCGTGGATCGAAAC	TCTATGGGAGGCTAGGGAGGCTACGCACCTTCAAAA
GTCGCTCCCCCCGCGGGGGCGTGGATCGAAAC

>NC_014034|5|4|1395365-1398068|CRISPRCasFinder
GTCGCTCCCCCCGCGGGGGCGTGGATCGAAAC	TGCACCCGCTGGCCCTGCCGGTGATCGGTGATCAGCG
GTCGCTCCCCCCGCGGGGGCGTGGATCGAAAC	ATCGCCGCTTTGGCGGTCGACAGGCTGGTAACGT
GTCGCTCCCCCCGCGGGGGCGTGGATCGAAAC	ATCTCGGTGCCGTCGCTCGTCCAGCCGGCCTGCTC
GTCGCTCCCCCCGCGGGGGCGTGGATCGAAAC	CACCTTGCGGATTGTCACTTTCGCGGGGCGAAGC
GTCGCTCCCCCCGCGGGGGCGTGGATCGAAAC	ATCTGCATGTAGTCGGCGGGCAGTTCGAGCCGCA
GTCGCTCCCCCCGCGGGGGCGTGGATCGAAAC	TGGTATGGATCTGGCGCAAACGGAAAGTCTGTC
GTCGCTCCCCCCGCGGGGGCGTGGATCGAAAC	CTGCGGCGTGAGTTGCCAGTGATAGACGCCGTGGAC
GTCGCTCCCCCCGCGGGGGCGTGGATCGAAAC	TGCGCCGCCTATCGCATCCGGTCGAGCGCCGCGCA
GTCGCTCCCCCCGCGGGGGCGTGGATCGAAAC	GATGCGTTCATGGCCTACGTCGGGCAGTGGACTG
GTCGCTCCCCCCGCGGGGGCGTGGATCGAAAC	TCGCCCTCGATCCGCGCTTGCCTCACGCCTGCCGC
GTCGCTCCCCCCGCGGGGGCGTGGATCGAAAC	AGGCGCATCTGATGTATATGCCCGGTGAGACGGCT
GTCGCTCCCCCCGCGGGGGCGTGGATCGAAAC	TTTTCGTCATCTGGCAGGCTCGCGCCGCCACGCTGC
GTCGCTCCCCCCGCGGGGGCGTGGATCGAAAC	CCGGCGAAAAACGGCCATGCCTCCGGGTGTCTGGCT
GTCGCTCCCCCCGCGGGGGCGTGGATCGAAAC	AGCAGGTCAGCCGCGGCCCCGGTGAACTTCTGTTC
GTCGCTCCCCCCGCGGGGGCGTGGATCGAAAC	AAGCAGTGGGGTGAGTGGGCTGACCAGACAAACGCT
GTCGCTCCCCCCGCGGGGGCGTGGATCGAAAC	CGCGCCCTGCGGGTGATGGCGACGGGCACCACGGCG
GTCGCTCCCCCCGCGGGGGCGTGGATCGAAAC	GGACCTGAAATTCCGCGGGAAACGCGGCGGCGAGCAC
GTCGCTCCCCCCGCGGGGGCGTGGATCGAAAC	TGCTTTCGTGGGACTGGCCAGCCGCCCGCGCCAA
GTCGCTCCCCCCGCGGGGGCGTGGATCGAAAC	GATTTCGTCGCTTACGACGCCTATCTGATTTCGG
GTCGCTCCCCCCGCGGGGGCGTGGATCGAAAC	CATGCGGCGATAACTCGCTCTTGCGATCCGTCATC
GTCGCTCCCCCCGCGGGGGCGTGGATCGAAAC	CCTGTCCCTCATATGCTGCCACGATGCCCTTGA
GTCGCTCCCCCCGCGGGGGCGTGGATCGAAAC	CGTGTGGATGATCATGCAGCGCGGACGGCTTGG
GTCGCTCCCCCCGCGGGGGCGTGGATCGAAAC	CGGTCCAGAGATAGACCGCGCGGACCTCCTCAGAC
GTCGCTCCCCCCGCGGGGGCGTGGATCGAAAC	AGCCTGCGCGGCCGCATCGGCTTCCGCCTGCGTG
GTCGCTCCCCCCGCGGGGGCGTGGATCGAAAC	ATCAGCTCGTCGTTGGTCAGCCGGACGATGTCC
GTCGCTCCCCCCGCGGGGGCGTGGATCGAAAC	TGCCGTCTTGAGTGATGGGGCGCGAGCACATGTC
GTCGCTCCCCCCGCGGGGGCGTGGATCGAAAC	GTCCAGCTCGCGCCACATGTCTTCGACCGTGCGCC
GTCGCTCCCCCCGCGGGGGCGTGGATCGAAAC	GTGTCTGCCACGACGCCCTGCACCAGATCCGCGCC
GTCGCTCCCCCCGCGGGGGCGTGGATCGAAAC	ACCGCGCACGCGCGAACGGCGTCAGCCCCGCGAAC
GTCGCTCCCCCCGCGGGAGCGTGGATCGAAAC	GGCTTTACAGCCTTCGCGCCCCACGCCAGACGGAC
GTCGCTCCCCCCGCGGGGGCGTGGATCGAAAC	TCTTCAATGGATATGGCAAAACCGTCCGCGACAT
GTCGCTCCCCCCGCGGGGGCGTGGATCGAAAC	ACCGTCATCACCACGCAACCGCCCTGCACCACCG
GTCGCTCCCCCCGCGGGGGCGTGGATCGAAAC	AACCCGATCATGGCCCGCCTCAGCGCCGCGCTGAC
GTCGCTCCCCCCGCGGGGGCGTGGATCGAAAC	ATCCGCGGATCGGCGTGACCCGCCCCGCCCATCG
GTCGCTCCCCCCGCGGGGGCGTGGATCGAAAC	TACAGAGTTCCGGTCTTGTTCTGTTCCGGTAACAG
GTCGCTCCCCCCGCGGGCGCGTGGATCGAAAC	TTGTCTGACGCGCTCATCAGCACGTCAAGATTCA
GTCGCTCCCCCCGCGGGGGCGTGGATCGAAAC	GGTGTCCAGCGTCACATGCAGCGGCGTCGCATCGCCAT
GTCGCTCCCCCCGCGGGGGCGTGGATCGAAAC	CCGGCACCTCAGCCCCGCCCGCTGTCTCACCAACA
GTCGCTCCCCCCGCGGGGGCGTGGATCGAAAC	TCTATGGGAGGCTAGGGAGGCTACGCACCTTCAAAA
GTCGCTCCCCCCGCGGGGGCGTGGATCGAAAC	CGCCGCGCAAAAAGCCCGCCAAGAAGCGGAGCAA
GTCGCTCCCCCCGCGGGGGCGTGGATCGTAAG

>NC_014034|5|3|1395365-1398068|CRT
GTCGCTCCCCCCGCGGGGGCGTGGATCGAAAC	TGCACCCGCTGGCCCTGCCGGTGATCGGTGATCAGCG
GTCGCTCCCCCCGCGGGGGCGTGGATCGAAAC	ATCGCCGCTTTGGCGGTCGACAGGCTGGTAACGT
GTCGCTCCCCCCGCGGGGGCGTGGATCGAAAC	ATCTCGGTGCCGTCGCTCGTCCAGCCGGCCTGCTC
GTCGCTCCCCCCGCGGGGGCGTGGATCGAAAC	CACCTTGCGGATTGTCACTTTCGCGGGGCGAAGC
GTCGCTCCCCCCGCGGGGGCGTGGATCGAAAC	ATCTGCATGTAGTCGGCGGGCAGTTCGAGCCGCA
GTCGCTCCCCCCGCGGGGGCGTGGATCGAAAC	TGGTATGGATCTGGCGCAAACGGAAAGTCTGTC
GTCGCTCCCCCCGCGGGGGCGTGGATCGAAAC	CTGCGGCGTGAGTTGCCAGTGATAGACGCCGTGGAC
GTCGCTCCCCCCGCGGGGGCGTGGATCGAAAC	TGCGCCGCCTATCGCATCCGGTCGAGCGCCGCGCA
GTCGCTCCCCCCGCGGGGGCGTGGATCGAAAC	GATGCGTTCATGGCCTACGTCGGGCAGTGGACTG
GTCGCTCCCCCCGCGGGGGCGTGGATCGAAAC	TCGCCCTCGATCCGCGCTTGCCTCACGCCTGCCGC
GTCGCTCCCCCCGCGGGGGCGTGGATCGAAAC	AGGCGCATCTGATGTATATGCCCGGTGAGACGGCT
GTCGCTCCCCCCGCGGGGGCGTGGATCGAAAC	TTTTCGTCATCTGGCAGGCTCGCGCCGCCACGCTGC
GTCGCTCCCCCCGCGGGGGCGTGGATCGAAAC	CCGGCGAAAAACGGCCATGCCTCCGGGTGTCTGGCT
GTCGCTCCCCCCGCGGGGGCGTGGATCGAAAC	AGCAGGTCAGCCGCGGCCCCGGTGAACTTCTGTTC
GTCGCTCCCCCCGCGGGGGCGTGGATCGAAAC	AAGCAGTGGGGTGAGTGGGCTGACCAGACAAACGCT
GTCGCTCCCCCCGCGGGGGCGTGGATCGAAAC	CGCGCCCTGCGGGTGATGGCGACGGGCACCACGGCG
GTCGCTCCCCCCGCGGGGGCGTGGATCGAAAC	GGACCTGAAATTCCGCGGGAAACGCGGCGGCGAGCAC
GTCGCTCCCCCCGCGGGGGCGTGGATCGAAAC	TGCTTTCGTGGGACTGGCCAGCCGCCCGCGCCAA
GTCGCTCCCCCCGCGGGGGCGTGGATCGAAAC	GATTTCGTCGCTTACGACGCCTATCTGATTTCGG
GTCGCTCCCCCCGCGGGGGCGTGGATCGAAAC	CATGCGGCGATAACTCGCTCTTGCGATCCGTCATC
GTCGCTCCCCCCGCGGGGGCGTGGATCGAAAC	CCTGTCCCTCATATGCTGCCACGATGCCCTTGA
GTCGCTCCCCCCGCGGGGGCGTGGATCGAAAC	CGTGTGGATGATCATGCAGCGCGGACGGCTTGG
GTCGCTCCCCCCGCGGGGGCGTGGATCGAAAC	CGGTCCAGAGATAGACCGCGCGGACCTCCTCAGAC
GTCGCTCCCCCCGCGGGGGCGTGGATCGAAAC	AGCCTGCGCGGCCGCATCGGCTTCCGCCTGCGTG
GTCGCTCCCCCCGCGGGGGCGTGGATCGAAAC	ATCAGCTCGTCGTTGGTCAGCCGGACGATGTCC
GTCGCTCCCCCCGCGGGGGCGTGGATCGAAAC	TGCCGTCTTGAGTGATGGGGCGCGAGCACATGTC
GTCGCTCCCCCCGCGGGGGCGTGGATCGAAAC	GTCCAGCTCGCGCCACATGTCTTCGACCGTGCGCC
GTCGCTCCCCCCGCGGGGGCGTGGATCGAAAC	GTGTCTGCCACGACGCCCTGCACCAGATCCGCGCC
GTCGCTCCCCCCGCGGGGGCGTGGATCGAAAC	ACCGCGCACGCGCGAACGGCGTCAGCCCCGCGAAC
GTCGCTCCCCCCGCGGGAGCGTGGATCGAAAC	GGCTTTACAGCCTTCGCGCCCCACGCCAGACGGAC
GTCGCTCCCCCCGCGGGGGCGTGGATCGAAAC	TCTTCAATGGATATGGCAAAACCGTCCGCGACAT
GTCGCTCCCCCCGCGGGGGCGTGGATCGAAAC	ACCGTCATCACCACGCAACCGCCCTGCACCACCG
GTCGCTCCCCCCGCGGGGGCGTGGATCGAAAC	AACCCGATCATGGCCCGCCTCAGCGCCGCGCTGAC
GTCGCTCCCCCCGCGGGGGCGTGGATCGAAAC	ATCCGCGGATCGGCGTGACCCGCCCCGCCCATCG
GTCGCTCCCCCCGCGGGGGCGTGGATCGAAAC	TACAGAGTTCCGGTCTTGTTCTGTTCCGGTAACAG
GTCGCTCCCCCCGCGGGCGCGTGGATCGAAAC	TTGTCTGACGCGCTCATCAGCACGTCAAGATTCA
GTCGCTCCCCCCGCGGGGGCGTGGATCGAAAC	GGTGTCCAGCGTCACATGCAGCGGCGTCGCATCGCCAT
GTCGCTCCCCCCGCGGGGGCGTGGATCGAAAC	CCGGCACCTCAGCCCCGCCCGCTGTCTCACCAACA
GTCGCTCCCCCCGCGGGGGCGTGGATCGAAAC	TCTATGGGAGGCTAGGGAGGCTACGCACCTTCAAAA
GTCGCTCCCCCCGCGGGGGCGTGGATCGAAAC	CGCCGCGCAAAAAGCCCGCCAAGAAGCGGAGCAA
GTCGCTCCCCCCGCGGGGGCGTGGATCGTAAG

Protein	Signature genes	Signature genes Name	Protein_function
NC_014034.1\|WP_080514588.1\|1401866_1402124_+\|SOS-response-associated-peptidase-family-protein	unknown	unknown	gnl\|CDD\|376837
NC_014034.1\|WP_013067048.1\|1409130_1413828_-\|hypothetical-protein	unknown	unknown	unknown
NC_014034.1\|WP_013067031.1\|1387447_1389712_+\|CRISPR-associated-endonuclease-Cas3''	cas3	COG1203_cas3_CAS-I	gnl\|CDD\|350688
NC_014034.1\|WP_013067042.1\|1402317_1402917_-\|hypothetical-protein	unknown	unknown	unknown
NC_014034.1\|WP_013067046.1\|1406609_1407524_+\|hypothetical-protein	unknown	unknown	unknown
NC_014034.1\|WP_157834359.1\|1379736_1380960_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|373965
NC_014034.1\|WP_013067032.1\|1389833_1390532_+\|type-I-C-CRISPR-associated-protein-Cas5	cas5	cd09752_cas5_CAS-I-C	gnl\|CDD\|187534
NC_014034.1\|WP_013067028.1\|1380962_1384055_+\|DEAD/DEAH-box-helicase	unknown	unknown	gnl\|CDD\|223627
NC_014034.1\|WP_013067044.1\|1404309_1405497_+\|DUF262-domain-containing-protein	unknown	unknown	gnl\|CDD\|377008
NC_014034.1\|WP_013067043.1\|1403064_1403901_-\|hypothetical-protein	unknown	unknown	unknown
NC_014034.1\|WP_013067036.1\|1393861_1394896_+\|type-I-C-CRISPR-associated-endonuclease-Cas1	cas1	cd09721_cas1_CAS-I-C	gnl\|CDD\|188360
NC_014034.1\|WP_013067035.1\|1393214_1393865_+\|CRISPR-associated-protein-Cas4	cas4	cd09637_cas4_CAS-I:CAS-II:CAS-V	gnl\|CDD\|273040
NC_014034.1\|WP_013067034.1\|1392264_1393215_+\|type-I-C-CRISPR-associated-protein-Cas7/Csd2	cas7	cd09689_cas7_CAS-I-C	gnl\|CDD\|377458
NC_014034.1\|WP_013067037.1\|1394897_1395188_+\|CRISPR-associated-endonuclease-Cas2	cas2	cd09725_cas2_CAS-I:CAS-II:CAS-III:CAS-V	gnl\|CDD\|187856
NC_014034.1\|WP_157834360.1\|1398736_1399888_-\|IS66-family-transposase	unknown	unknown	gnl\|CDD\|376980
NC_014034.1\|WP_013067033.1\|1390528_1392268_+\|type-I-C-CRISPR-associated-protein-Cas8c/Csd1	cas8c	cd09757_cas8c_CAS-I-C	gnl\|CDD\|273839
NC_014034.1\|WP_013067040.1\|1400692_1400920_-\|hypothetical-protein	unknown	unknown	unknown
NC_014034.1\|WP_013067030.1\|1386762_1387389_+\|WYL-domain-containing-protein	WYL	COG2378_WYL_CAS-I:CAS-III	gnl\|CDD\|225253
NC_014034.1\|WP_013067047.1\|1407817_1408726_-\|pirin-family-protein	unknown	unknown	gnl\|CDD\|224655
NC_014034.1\|WP_013067045.1\|1405489_1406608_+\|DUF3696-domain-containing-protein	unknown	unknown	gnl\|CDD\|227274

Protein	Function_ID	Function_description	E-value
NC_014034.1\|WP_080514588.1\|1401866_1402124_+\|SOS-response-associated-peptidase-family-protein	gnl\|CDD\|376837	pfam02586, SRAP, SOS response associated peptidase (SRAP). The SRAP family functions as a DNA-associated autoproteolytic switch that recruits diverse repair enzymes onto DNA damage. We propose that the human protein Q96FZ2:UniProtKB, the eukaryotic member of the SRAP family, which has been recently shown to bind specifically to DNA with 5-hydroxymethylcytosine, 5-formylcytosine and 5-carboxycytosine, is a sensor for these oxidized bases generated by the TET (tetrahedral aminopeptidase of the M42 family) enzymes from methylcytosine. Hence, its autoproteolytic activity might help it act as a switch that recruits DNA repair enzymes to remove these oxidized methylcytosine species as part of the DNA demethylation pathway downstream of the TET enzymes.	7.65816e-11
NC_014034.1\|WP_013067031.1\|1387447_1389712_+\|CRISPR-associated-endonuclease-Cas3''	gnl\|CDD\|350688	cd17930, DEXHc_cas3, DEXH/Q-box helicase domain of Cas3. CRISPR-associated (Cas) 3 is a nuclease-helicase responsible for degradation of dsDNA. The two enzymatic units of Cas3, a histidine-aspartate (HD) nuclease and a Superfamily 2 (SF2) helicase, may be expressed from separate genes as Cas3' (SF2 helicase) and Cas3'' (HD nuclease) or may be fused as a single HD-SF2 polypeptide. The nucleolytic activity of most Cas3 enzymes is transition metal ion-dependent. Cas3 is a member of the DEAD-like helicase superfamily, a diverse family of proteins involved in ATP-dependent RNA or DNA unwinding. This domain contains the ATP-binding region.	1.62784e-55
NC_014034.1\|WP_157834359.1\|1379736_1380960_+\|hypothetical-protein	gnl\|CDD\|373965	pfam15611, EH_Signature, EH_Signature domain. This domain with a strongly conserved glutamate at the N-terminus and a histidine at the C-terminus, is found in a SWI2/SNF2 four gene operon. Its strict-neighborhood association with SWI2/SNF2 ATPase strongly suggests a function in conjunction with it. The other genes in the operon are a OmpA protein and a TM protein. This has a DNA related function along with the TerY-P triad.	6.44134e-58
NC_014034.1\|WP_013067032.1\|1389833_1390532_+\|type-I-C-CRISPR-associated-protein-Cas5	gnl\|CDD\|187534	cd09752, Cas5_I-C, CRISPR/Cas system-associated RAMP superfamily protein Cas5. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas5 is a RAMP superfamily protein; Subunit of the Cascade complex; in subtype I-C this protein might be the endoribonuclease that generates crRNAs; also known as DevS family.	1.14695e-106
NC_014034.1\|WP_013067028.1\|1380962_1384055_+\|DEAD/DEAH-box-helicase	gnl\|CDD\|223627	COG0553, HepA, Superfamily II DNA/RNA helicases, SNF2 family [Transcription / DNA replication, recombination, and repair].	1.81228e-57
NC_014034.1\|WP_013067045.1\|1405489_1406608_+\|DUF3696-domain-containing-protein	gnl\|CDD\|227274	COG4938, COG4938, Uncharacterized conserved protein [Function unknown].	5.72611e-59
NC_014034.1\|WP_013067036.1\|1393861_1394896_+\|type-I-C-CRISPR-associated-endonuclease-Cas1	gnl\|CDD\|188360	TIGR03640, cas1_DVULG, CRISPR-associated endonuclease Cas1, subtype I-C/DVULG. The CRISPR-associated protein Cas1 is virtually universal to CRISPR systems. CRISPR, an acronym for Clustered Regularly Interspaced Short Palindromic Repeats, is prokaryotic immunity system for foreign DNA, mostly from phage. CRISPR systems belong to different subtypes, distinguished by both nature of the repeats, the makeup of the cohort of associated Cas proteins, and by molecular phylogeny within the more universal Cas proteins such as this one. This model is of type EXCEPTION and provides more specific information than the EQUIVALOG model TIGR00287. It describes the Cas1 protein particular to the DVULG subtype of CRISPR/Cas system.	0
NC_014034.1\|WP_013067035.1\|1393214_1393865_+\|CRISPR-associated-protein-Cas4	gnl\|CDD\|273040	TIGR00372, conserved_hypothetical_protein, CRISPR-associated protein Cas4. This model represents a family of proteins associated with CRISPR repeats in a wide set of prokaryotic genomes. This scope of this model has been broadened since it was first built to describe an archaeal subset only. The function of the protein is undefined. Distantly related proteins, excluded from this model, include ORFs from Mycobacteriophage D29 and Sulfolobus islandicus filamentous virus and a region of the Schizosaccharomyces pombe DNA replication helicase Dna2p.	4.03501e-37
NC_014034.1\|WP_013067034.1\|1392264_1393215_+\|type-I-C-CRISPR-associated-protein-Cas7/Csd2	gnl\|CDD\|377458	pfam05107, Cas_Cas7, CRISPR-associated protein Cas7. CRISPR-associated protein Cas7 is one of the components of the type I-B cascade-like antiviral defense complex. In Haloferax volcanii, Cas5, Cas6 and Cas7 form a small complex that aids the stability of CRISPR-derived RNA.	7.22287e-150
NC_014034.1\|WP_013067037.1\|1394897_1395188_+\|CRISPR-associated-endonuclease-Cas2	gnl\|CDD\|187856	cd09725, Cas2_I_II_III, CRISPR/Cas system-associated protein Cas2. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas2 is present in majority of CRISPR/Cas systems along with Cas1; RNAse specific to U-rich regions; Possesses an RRM/ferredoxin fold.	1.08624e-33
NC_014034.1\|WP_157834360.1\|1398736_1399888_-\|IS66-family-transposase	gnl\|CDD\|376980	pfam03050, DDE_Tnp_IS66, Transposase IS66 family. Transposase proteins are necessary for efficient DNA transposition. This family includes IS66 from Agrobacterium tumefaciens.	8.95851e-67
NC_014034.1\|WP_013067033.1\|1390528_1392268_+\|type-I-C-CRISPR-associated-protein-Cas8c/Csd1	gnl\|CDD\|273839	TIGR01863, CRISPR-associated_protein_CT1133_family, CRISPR-associated protein Cas8c/Csd1, subtype I-C/DVULG. CRISPR loci appear to be mobile elements with a wide host range. This model represents a protein that tends to be found near CRISPR repeats of the DVULG subtype of CRISPR/Cas locus. We designate this family Csd1 (CRISPR/Cas Subtype DVULG protein 1). The species range for this subtype, so far, is exclusively bacterial and mesophilic, although CRISPR loci in general are particularly common among archaea and thermophilic bacteria. In a few species (Xanthomonas axonopodis pv. citri str. 306 and Streptococcus mutans UA159), homology to this protein family is split across two tandem genes; the trusted cutoff to this family is set low enough to capture at least the longer of the two.	0
NC_014034.1\|WP_013067044.1\|1404309_1405497_+\|DUF262-domain-containing-protein	gnl\|CDD\|377008	pfam03235, DUF262, Protein of unknown function DUF262.	1.03836e-22
NC_014034.1\|WP_013067030.1\|1386762_1387389_+\|WYL-domain-containing-protein	gnl\|CDD\|225253	COG2378, COG2378, Predicted transcriptional regulator [Transcription].	1.34945e-10
NC_014034.1\|WP_013067047.1\|1407817_1408726_-\|pirin-family-protein	gnl\|CDD\|224655	COG1741, COG1741, Pirin-related protein [General function prediction only].	3.25263e-79

>NC_014034.1|WP_013067037.1|1394897_1395188_+|CRISPR-associated-endonuclease-Cas2
MLVLVTYDVNTLEEGGKKRLRRVAKACEDFGQRVQFSVFEIEVDPGQWVKLKARLEAVIRPEFDSLRYYYLGSNWERNVEHVGAKPALDLNGPLIL
>NC_014034.1|WP_013067036.1|1393861_1394896_+|type-I-C-CRISPR-associated-endonuclease-Cas1
MKKLLNTVYVTTEGAALRLEGETLVAEIEGADKTRVPLHMLASVVVFGPVLLTPALIAVCAERGITLALMGRNGRFQARVEGPVSGNVLLRREQYRRADSPEEIVRSFVLGKVSNQRAVIRRALRDYGDDMAPPARAALETAADRMAQILRRVQLADASVEAMRGSEGEAANLYFAVFDHLIRAPDAELRWTLRSRRPPLDPMNALVSFLYTLLTHDCRSACEAVGLDPAVGFLHRDRPGRPSLALDLMEELRAPLADRLALSLVNRRQLRAADFRQMEGGAVLLTDDARRSVLTAWQDRKREERLHPFLQEKAPFGLVPFLQAQMLARHLRGDIDAYPPWFWS
>NC_014034.1|WP_013067035.1|1393214_1393865_+|CRISPR-associated-protein-Cas4
MPAPPAEEETIPLSALQHAVYCLRQAALIHLERLWDENIFTAQGDVLHAVADKGGSRKGRGGRRVLSLPLGSVRLNLSGTADLVEFQPQPDGSERPFPVEYKRGKPKLHRADEAQLCAQALCLEEMTGQPVPEGALYYAQTKRRVTVPIDAELRALTMAAVADLAEVFARRTTPPPTPHRSRCRACSLIDLCRPETVARPVKRWRDQTLARLLEAR
>NC_014034.1|WP_013067034.1|1392264_1393215_+|type-I-C-CRISPR-associated-protein-Cas7/Csd2
MIPLSRRHDFVLIFDVTNGNPNGDPDAGNLPRLDPETNHGLVSDVSLKRKLRNYVELARTGEAGHHIYVQEGAILNEKHRQAYVAIRGDEKSKKDAKLNPKDDTEAKALRDWMCANFFDVRTFGAVMSTGVNCGQVKGPVQMTFARSVEPILPVEISITRMAATNEAEQKKRAEGEDGDTRTDNRTMGRKHIVPYGLYVAHGFISAKFAERTGFSEADLDLLFEALANMFEHDRSAARGEMTTRKLIVFAHENALGNAPAHALFDRIRIGRAVDGEFRNLDDRGLGNLAPARKFSDYRVEIDREGLPAGVEIRELL
>NC_014034.1|WP_013067033.1|1390528_1392268_+|type-I-C-CRISPR-associated-protein-Cas8c/Csd1
MSLLASLVRAYERMPDAPPYGYSTEKIGFCVVLTAAGEVVEVADLRDTDKKRSPRMLMVPQAVKRTVGIAPNFLWDKSAYVLGVTAGEGKRTAEEHAKFRERHLTALAGAEDPGLLALARFLQTWTPEAFGPPLWPEEAKDQNLVFRLADEFGYLHDRPAARALWARLGAEAASEAQVCLVTGASAPVARLHPSLKGVWGAQSSGASLISFNLDAFNSYGHEQGDNAPVSEGAAFAYTTALNRFLEKDSGHRLQIGDASTVFWADASEAEAAQAEGFFAAFFDTAATEKIEALNIGAQLARIRACEPLAEVAPQLASGVRFCVLGLAPNAARLSVRFWWEDDFGTLTAHYQRYLDDMRLDPPPRDDWPPLWRYLSELAPQGKRENVPPLIAGDWMRAILTGTAYPLTLLSTVLMRIRADGEINALRAAMLKSVLIRNFQSKEAPVALDPASKDTGYVLGRLFAAYENIQKAALGKGVNATIRDKFYGSASATPARVFGSLAANAFNHLAKIRKEKPAFAHYLQDELQQIANLLEVSAEPFPSSLSQESQAKFALGYYHQASFRKPADTEQEPHSEEQPQ
>NC_014034.1|WP_013067032.1|1389833_1390532_+|type-I-C-CRISPR-associated-protein-Cas5
MAYGIRLHVRGRHALFTRPELKVERVSYDVMTPSAARGILEAIHWKPAISWVIDRIHVLEPIRFQSIRRNEVGHKAPTGSIKQAMNRGDLAGLQILVDEDRQQRASTVLVAPAYVIEAHFTLTAKAGAEDSEGKHLDIFNRRAARGQCFHQPCLGTREFAADFALLAPDAALPARNPLAETADLGFGTPRDLGLMLWDIDHAAPGRPSMFFRARLVEGVMEVPRPGSPEVLR
>NC_014034.1|WP_013067031.1|1387447_1389712_+|CRISPR-associated-endonuclease-Cas3''
MTHYAHSGTQADRSDWQTLLDHLRMVALLAQDRGAAFGLGAAAELAGRLHDLGKYDPAFDRVLCGEPGPVVDHSTAGGRVLLDPASGCPKPVAEALAQTILGHHAGLPDTNSPEDGGCLVARIARPGAALAAQASADMPEDFNAVSDEFRRKLRKDKAGFDFSVATRMVFSCLVDADYRDTEAFYDALEGRSRDRDWPALQSLLPAFRARFDAHMAAFDPGTDLNRLRAEILAQVRAKAALPPGLITLSVPTGGGKTLASLGFALDHAACHGHRRIIYAIPFTSIIDQTVQVFADLLGAENVLEHHSAIEIETPGPGRREAADTKDRSRDKVRQAMEDWAAPVVVTTNVQLFESLFAARPSRCRKLHNIAGSVIVLDEAQCLPRKVLLPTLAMLDTLCAHYGCTVVLCTATQPAFDSAQLQPGGLALAGRELAPDPGTLAGRLRRARIVQGGAMDDAGLVAALAATPQGFVIVNSRRHALALYRAAEAAGLEGLLHLTTRQYPAHRREIIEQIRARLKAGQPCRLIATSLIEAGVDLDFPCGWRAEAGLDSVIQAAGRVNREGKRPLDASVLTVFSAPDNAPPGDVAQLAGAMQSVARGCDDLLDPAAIRRWFEEVYWRAGPKRLDAEGLMDRFTFDGSATNFAFRTVAERYRMIDSPMVPVIVARDETAADWVARLSNEWEKSGPLARALQPFTVQIPQRARETLRANDKGDFEAAPLRGDAFFVLSDGGLYRDDFGLWWEQADYLSADQSVI
>NC_014034.1|WP_013067030.1|1386762_1387389_+|WYL-domain-containing-protein
MGDLDGRAASLVLTRRGLGARLAGAVLAGGVGGGSAVAAVPAPDPDLRDAALRGLALAQHRGDPVTAAAARAALARLAETDPEAAILTRLYQLLDVRPAAYWQEAAANEPPARAEDLAVLHGAIRACAPVAFGYTDRGGTVTTRRALPLALVHPAQGVKLLAFCETREGFRQFFVRAMTGLSLQPGDFSADRGALLQGLLEKEEGGPL
>NC_014034.1|WP_013067028.1|1380962_1384055_+|DEAD/DEAH-box-helicase
MNLTFSHTPEQITLTATASRGGLLNRLRARKPADLTLLPPEERRLALALADLRALADEHHEPLQIESDGIRLSHRLAAALDADAAEALGLPPLTDLVLRTDVEGIVGEAGFRLRAEWMRAGVRKLPRRVGAILETDRGPQRIPLWMMEALDLAESHRSGAGDAADWEALARFRRALDPGVVQAGNVRAARLSLTDFLAGLEVSLADRFSISPNASGSDFEVVPFSGQRIADLETVPETMAELSGPELGDFQRKLRMRGALNAFRLAPGRFLVIDRAAAPVLGVMAEMQRAPREERAAFIRNPRPRLTAAIEAALEARGDLAGLDDAAREDSIERAAGPVLVETAEYEAFSARVTGIELFEKPALDLFTGSGTTWLPEVFAADVARQIAELPVERLETLAQDLERAIAAGEVSVAAGDVQVPARPEALAAVQGEIIARRGQPEPTEAALQEHAPGPLVLQTADNFEELHWRPATPPRSAVLPLRLPHTLRTPLKDHQIEAFDWQGQAWRAGLPGVLNADEQGLGKTLQTIAFLVWLNEEMTANPIRRGPVLVVAPTSLLQNWEQEVARHVDAPGLGHLIRLYGTGIGARRKAGQRGMDTQSGEALLDFADLERAAAAGAGHLTWVLTTYTTLTNYQHSLARIPFAAAVFDEIQAIKNPASLRAAAARAVKADFRIGLTGTPIENSTVDLWAIMDQLAPGALGTLREFRSRYGEPDEANMAELHARVFTPQGGLPALALRRMKDKVARDLPAKTRVLVPREMPALQAQVYDAARLQLASGTPGAALKLLHHIRTVSVHPALGSYGADAEFIAASARLSATFDILRQIRARGERALVFIENRQMQYRFIEIARAEFGLARIDLINGDTPIAQRQQIVNRFQAHLEDGGGFDLLVLGPKAAGTGLTLTAATHVIHLSRWWNPAVEEQCNDRVHRLGQTRPVQIHVPMAIHPGYRAHSFDCLLHTLMQRKRRMASAALWPMGDTDTDAQHLRGMVAQDVIGQGRGQIVPQAMAETFAREGVACPEPGEGGRYAFE
>NC_014034.1|WP_157834359.1|1379736_1380960_+|hypothetical-protein
MIERFGAHAQIAERDPERLISEMLARIRAWDWQKVPMRHVNAVGRLVFAAPWRDRPDCDPIRTFLLDEVAVSTRSGFLNPLVQTYITTFSTQSAACRRLGQALARARERLGAQWRALLTEVPEFFDTDRAPQALARKMMQMEDIWRGLRKLGLRHFNELGLMDAAHLAYLEQIGPKLTDRAEIERLLAWLRPAGQPPRATGAAEAIAALLRPWAGKAVPEDLRALICERLIEIYGDPRPVPNATWLAVGEDNLALFRRWLTKAELTFFIGVVNATQNSDMWPPRRDFWELLYRQGRIAEAWVAFPKPARDYARRNLQLWGQGNDRRFGEQIAGGSRTNTSLLIMRIGDKIVVDGCHSYKTHIFDAKDPQAPKLYQRKYDCEDIRLRSRVSRAHNPIPNWSDWVLRHI
>NC_014034.1|WP_157834360.1|1398736_1399888_-|IS66-family-transposase
MWEKHIYFRCACNRSAACKEHKPVSAHAEGFIGRRRTITPRTVVEAVCQKFYEHSTHYRQRRRLDNAGFNVARQTLGRNATHIAGFLEPVCDELWRHVTSGHAAHMDETPLRTQAKGGCETTWLWGLCRDERGWNKEAEPAVYCEHDASRGGHVAERMLEGALIDTLQIDGWKAYNRIRRVPGQNDGVEIARCMAHARRKFTDSQKAAPSTLAKRVIKGLKAVYEVEERVYGCPPEERQALRLAEALPVLEKIRADLLRVQPDLAKGSLKTAVNYFLSGWEDLTRYVYDGRLAIDNNPVERCMRGIALSKKNSLFAGNLMAAKNWAIFYSLIETARLNGVDPFRYLSWVIDQIEKGRELTDYSQLMPWHFKAANEAPSQGKAA
>NC_014034.1|WP_013067040.1|1400692_1400920_-|hypothetical-protein
MNGEAKNEEKDEKGIKFLFMNDFFRFWRFRAMTLIVPRAIPGDRNDLHLTPENENAGMLAHPDVDVMWKAEAHQH
>NC_014034.1|WP_080514588.1|1401866_1402124_+|SOS-response-associated-peptidase-family-protein
MGPHPVMVRGRQPEAWKAATFNARIEDAREKPAFRQVWRHGRCLVPVGDFYEWSGPKAASRISSPPPETRRTCIWRDWRAAGAIF
>NC_014034.1|WP_013067042.1|1402317_1402917_-|hypothetical-protein
MKISVNQFIDFAYGDKRKDKTKAASIIDDLDVPYDPAKDRYKQFREALASFEDGKVSTSEFLTLHSGVSANKSAGYKILCKNYLDLKEDYALIWQGRSPVEAEISGLRITTAWYLRTEENNQRRIIFLHFGKEQLPREKERGLLTVLRLAKPDSAGVGILNIQPGTLVTSTRIDQIEADYLRKRAEKFMAIAKDILAGR
>NC_014034.1|WP_013067043.1|1403064_1403901_-|hypothetical-protein
MADGNYLRDERLRVYLSAHTHHRLVLADLTLTEMFKKNALGTARSSLKIMADFPDQIFALKPTHLWLDAKVCSEADLQQLIDPDRSADIRQLTRDYRSEEAIPSFVERMKAREGEASQYMRQLSDQVRTLEISLQSLLKEFRVEELTQIRTGQGITSTLQEKIFNLVDEVTVEFVKTNQEPGRTAPLKRSEAHGMFAYRYALCVVIAFTRWVELGRQVKSLDHRLNDVVDNQLAATSTYFNEVLTKDRELRIVASNAKDVLKHLGAFTRPFPDEASAG
>NC_014034.1|WP_013067044.1|1404309_1405497_+|DUF262-domain-containing-protein
MATQTIITDPQRMTEEGTSFGTPSGIERELPSELGNDLQIAEPFNPDDIDVTTRSMTIDLLLSRMRSKAIDLEPDFQRRRGIWTDRQQSRLIESLLLRIPLPTLYAAEDEEENWAIVDGIQRLTTITRFIDPEAIGETPLMLTGLEYLGESFNEKLFDDLPARLKRRLRETELVVHVIRHGTPQEVKFNIFARINTGGMPLSAQELRHALIPGKARNYLSRLAGLEAFKQATANSIRDERMADREMVLRFLAFSMTDPKEFRAYDFDRFLGDAMREINRLNNRDLERLEDGFTRAMESALEIFGQDAFRKRYRETDARFPINKALFETIAVSLSNLSDSERARCILRHDEVRRRMMEAMHDREFDAAISQGTGDIRKVRKRFETVLKIFKDISDV
>NC_014034.1|WP_013067045.1|1405489_1406608_+|DUF3696-domain-containing-protein
MFDALTLHNFKAFRDVHIPLKPLTLLSGLNGSGKSTTLQALALLRQSWDAGFLSRQGFLLNGDLVELGTGVDVLNDQHEDEDIGITLFDREERAFAYRVAYEPRGDLLHFSADPNFSFYSDLEHQRGLFGHWFQYLRADRAGPEVSFPKAYHLVNERRFLGSRGQYTAHFLSLFGDEEVNPVLRHPDEAAPGLLSQVNAWFQEFSPGVGLAVEDIPRTDAVRLDYFYGGSAGISGSNPYRSTNVGFGLTYVLPILVACLASPPDSWLLIENPEAHLHPQGQAAMGQLMARSAATGTRIVVESHSDHFLNGIRLAVKNGEIPAGDVGLNFFRRPSGSSQPERIHPVVTPEGRLSEWPDGFFDQWDKSLDQLLS
>NC_014034.1|WP_013067046.1|1406609_1407524_+|hypothetical-protein
MTFIAFLNELSFPSGAVDAEAAEAAVVGLAKTLQSLRQIQSSAALHSSVPLASIPLGDDRWLGTVMAKGRSRDEWRFLRSFENRAPFRVNLGEAFGLEAEYRYGDVLAEGLGLGHIVGTLGVSFANEPWLAPTVPLRRISFDEHGGFEERVVHVHHAATPDHVKGHDEWLRRIPSEQVRDGDELWARRAEIFPHLLFLPRTEAHLRAFKAGEPRLSSARQALMDLEIAAAHWNTKDAAMPTFLTKTTPEKEQRSKLFYFIDLSGVERCFDWHSRYTPGAGRVHFWCDRSSGRLTIAHVGEKVPN
>NC_014034.1|WP_013067047.1|1407817_1408726_-|pirin-family-protein
MTFRPVLATSKAQPAIEGAGVHLHRVFGFGDPALTDPFLMMDDFRNDDPRLYAKGFPWHPHRGIETITYVLEGQVEHADSLGNRGLLGAGGVQWMTAGSGIVHQEMPFGNAQGQMHGFQLWANLPAALKMTAPRYQDVGAGDIPVEGDDDGTTVKVIIGTFWGKTGPVDGIAANPMLLDVSVPPGRRKALSVDTRANALAYVFAGSGTFRDASDPVGIKVEKEYRGQEMTLRDRTGNRTLVRFGAGDAITVQAGDEGIRFLLMTGRPIQEPVAWHGPIVMNTQEELRQALRELNDGTLIKHG
>NC_014034.1|WP_013067048.1|1409130_1413828_-|hypothetical-protein
MARNMTTQISHTVPPGDLARSGLTGVARHLLSVSVIALLFGLSPAAAQFRIDRNTEASEESSGVIQGTVGYLADTTTATGGDNLGDHVATMPLNMSGFSISGIATPDGTDPGAGVNVQYVDDMFGAYTPPEQDLSNYVTKSGMPQTITSAKTFDGPVLFSDDVQVTKVPASTRDVTNKAYVDDAVDDLVTLTTNQSVSGDKSFTGSVAVRTPTGDMGAANKLYVDNAISVAGGSYVTMGTNQIIGGTPITGAKGFTDAVTFGGEVNVTSAPDDANDAANKAYVDSLTDGLAGRVTVLEGDVTALTASVTTLQGDVSTLDTRVTNLANRTITAGSGITASGTLGGGITVAVDPTVVRTSGNQTLAGVKNFSSLPTVPTAAPTLAGQVASKAHVDAQVASAVGTTYAAGDGLSLAGTTFAVNGTVVRTTGDQTLAGVKTFSAPIAGSITGNAATATKLAAAKTINGVAFDGSAGITLPTVNTTGAQAVAGVKTFSDIPVIPITAPTVAGQVASKAYVDAQVAGAVGTTYAAGDGLCLAGTTFAVDGTVVRTSGDQTLAGVKTFSAPIAGSITGNAATATELQTARTINGVAFDGGANITLPTVNTTGAQTVAGVKTFSSPIAGSITGNAATASELQTARTINGVAFDGGANITLPTVNTTGAQAVAGVKTFSDIPVIPTTAPTVAGQVASKAYVDAQVAGAVGTTYTAGSGLSLTGTTFAADGTVVRTSGDQTLAGVKTFSAPIAGSITGNAATATKLASARTINGVAFDGTAGITLPTVNTTGAQAVAGVKTFSDIPILPVTAPTSDLQAVNKAYADTKFGIGSVLSTTDDFDDVLMSGYHKATTGISTAAALALNRPSGQPGMLEVLNNGGSIMQRYSTINSTGTFYRTRNSSGVWFAWKPFASYNAGDGIDLDVTTQTFAVDATVVRTTGTQSIAGTKTFSGALTATGTVNLSTTSYVPTMGTTSTALVNKGYVDGGFVDLTTAETIGGTKTFSAIPVIPTTAPTAAGQVASKAYVDSKVGATYTAGDGLSLTGTDFAVDGTVVRTAGAQTLAGVKTFMSPIAGSITGNAATATKLAAAANINGVAFDGSAAITLPTVNTSGAQAVAGLKTFSTIPQIPTSTPTLAAEVASKGYVDSKIVAASSYAAGSGLALSGNVFSADNTVVRTSGAQTLSGVKTFNDLPLLPAATPTLDNQVASKAYADTKFGAGAALTTTDDFNTVVDTNFYKVSTGIATAAAIALNRPSGQPGILEVVNNGNVLVQRYSTLGAKGTFYRTRTSAGTWASWASVADYGAGDGLTLDAATNDFAVDDTVIRDSGAQSIAGTKTFTGTLTGTGTVNLPAATYVPTMGTTSTAVANKAYADTKVSMTGNQAISGVKSFAAFPTVPVATDPTADNQVVSKKYADSLALNITRSLMLPYFNILVRATDSLASTGTARHDKITIAAVPVDMKRVVCFTLTRNSSFVGDDSFEKEECYIVQEGDVIEVKSSSFGAVVIAINNEDQVNDFSFPSRTKISGPFLFIDEQSPASTPFIYNFSGYSNHEGSSQLSTSISVREYLMPNVSP

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Crispr_ID: NC_014034_6

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_014034_6

1434284-1434909

Orphan

I-C

Consensus_repeat	Method
GTCGCTCCCCCCGCGGGGGCGTGGATCGAAAC	CRT
GTCGCTCCCCCCGCGGGGGCGTGGATCGAAAC	PILER-CR
GTCGCTCCCCCCGCGGGGGCGTGGATCGAAAC	CRISPRCasFinder

9 spacers

The CRISPR arrays of NC_014034_6

>merge|NC_014034|6|1434284-1434909|CRT,PILER-CR,CRISPRCasFinder
GGGTATATGCACCGCTTACCGTGGATCGAAACAGGCTGCTTTGGGCGGAACACCTGATCCTGCTGGGTCGCTCCCCCCGCGGGGGCGTGGATCGAAACGTCTCCGCTCTGCTTCACGGCTGCGTCAACCTTGTCGCTCCCCCCGCGGGGGCGTGGATCGAAACACGGATTGCATGGCGCCGAGGGACAGGCTTTGCAGTCGCTCCCCCCGCGGGGGCGTGGATCGAAACCGCCCGCGGCGTTTGACCTGGTCGCGGGCAGCTGGTCGCTCCCCCCGCGGGGGCGTGGATCGAAACGACGCGCTGAAGGAGGGTGATCTCGGTGGCGCCTTGTCGCTCCCCCCGCGGGGGCGTGGATCGAAACACGGATTGCATGGCGCCGAGGGACAGGCTTTGCAGTCGCTCCCCCCGCGGGGGCGTGGATCGAAACCGCCCGCGGCGTTTGACCTGGTCGCGGGCAGCTGGTCGCTCCCCCCGCGGGGGCGTGGATCGAAACGACGCGCTGAAGGAGGGTGATCTCGGTGGCGCCTTGTCGCTCCCCCCGCGGGGGCGTGGATCGAAACATGGAAAACCGCGGCTTCACCGCGCGGGATTGGGTCGCTCCCCCCGCGGGGGCGTGGATCGAAAC

>NC_014034|6|4|1434284-1434909|CRT
GGGTATATGCACCGCTTACCGTGGATCGAAAC	AGGCTGCTTTGGGCGGAACACCTGATCCTGCTGG
GTCGCTCCCCCCGCGGGGGCGTGGATCGAAAC	GTCTCCGCTCTGCTTCACGGCTGCGTCAACCTT
GTCGCTCCCCCCGCGGGGGCGTGGATCGAAAC	ACGGATTGCATGGCGCCGAGGGACAGGCTTTGCA
GTCGCTCCCCCCGCGGGGGCGTGGATCGAAAC	CGCCCGCGGCGTTTGACCTGGTCGCGGGCAGCTG
GTCGCTCCCCCCGCGGGGGCGTGGATCGAAAC	GACGCGCTGAAGGAGGGTGATCTCGGTGGCGCCTT
GTCGCTCCCCCCGCGGGGGCGTGGATCGAAAC	ACGGATTGCATGGCGCCGAGGGACAGGCTTTGCA
GTCGCTCCCCCCGCGGGGGCGTGGATCGAAAC	CGCCCGCGGCGTTTGACCTGGTCGCGGGCAGCTG
GTCGCTCCCCCCGCGGGGGCGTGGATCGAAAC	GACGCGCTGAAGGAGGGTGATCTCGGTGGCGCCTT
GTCGCTCCCCCCGCGGGGGCGTGGATCGAAAC	ATGGAAAACCGCGGCTTCACCGCGCGGGATTGG
GTCGCTCCCCCCGCGGGGGCGTGGATCGAAAC

>NC_014034|6|6|1434350-1434909|PILER-CR
GTCGCTCCCCCCGCGGGGGCGTGGATCGAAAC	GTCTCCGCTCTGCTTCACGGCTGCGTCAACCTT
GTCGCTCCCCCCGCGGGGGCGTGGATCGAAAC	ACGGATTGCATGGCGCCGAGGGACAGGCTTTGCA
GTCGCTCCCCCCGCGGGGGCGTGGATCGAAAC	CGCCCGCGGCGTTTGACCTGGTCGCGGGCAGCTG
GTCGCTCCCCCCGCGGGGGCGTGGATCGAAAC	GACGCGCTGAAGGAGGGTGATCTCGGTGGCGCCTT
GTCGCTCCCCCCGCGGGGGCGTGGATCGAAAC	ACGGATTGCATGGCGCCGAGGGACAGGCTTTGCA
GTCGCTCCCCCCGCGGGGGCGTGGATCGAAAC	CGCCCGCGGCGTTTGACCTGGTCGCGGGCAGCTG
GTCGCTCCCCCCGCGGGGGCGTGGATCGAAAC	GACGCGCTGAAGGAGGGTGATCTCGGTGGCGCCTT
GTCGCTCCCCCCGCGGGGGCGTGGATCGAAAC	ATGGAAAACCGCGGCTTCACCGCGCGGGATTGG
GTCGCTCCCCCCGCGGGGGCGTGGATCGAAAC

>NC_014034|6|5|1434350-1434909|CRISPRCasFinder
GTCGCTCCCCCCGCGGGGGCGTGGATCGAAAC	GTCTCCGCTCTGCTTCACGGCTGCGTCAACCTT
GTCGCTCCCCCCGCGGGGGCGTGGATCGAAAC	ACGGATTGCATGGCGCCGAGGGACAGGCTTTGCA
GTCGCTCCCCCCGCGGGGGCGTGGATCGAAAC	CGCCCGCGGCGTTTGACCTGGTCGCGGGCAGCTG
GTCGCTCCCCCCGCGGGGGCGTGGATCGAAAC	GACGCGCTGAAGGAGGGTGATCTCGGTGGCGCCTT
GTCGCTCCCCCCGCGGGGGCGTGGATCGAAAC	ACGGATTGCATGGCGCCGAGGGACAGGCTTTGCA
GTCGCTCCCCCCGCGGGGGCGTGGATCGAAAC	CGCCCGCGGCGTTTGACCTGGTCGCGGGCAGCTG
GTCGCTCCCCCCGCGGGGGCGTGGATCGAAAC	GACGCGCTGAAGGAGGGTGATCTCGGTGGCGCCTT
GTCGCTCCCCCCGCGGGGGCGTGGATCGAAAC	ATGGAAAACCGCGGCTTCACCGCGCGGGATTGG
GTCGCTCCCCCCGCGGGGGCGTGGATCGAAAC

Protein	Signature genes	Signature genes Name	Protein_function
NC_014034.1\|WP_115503939.1\|1442582_1442903_+\|hypothetical-protein	unknown	unknown	unknown
NC_014034.1\|WP_013067056.1\|1427422_1428361_+\|hypothetical-protein	unknown	unknown	unknown
NC_014034.1\|WP_013067064.1\|1439266_1441576_+\|hydantoinase-B/oxoprolinase-family-protein	unknown	unknown	gnl\|CDD\|223224
NC_014034.1\|WP_023911249.1\|1442287_1442503_+\|hypothetical-protein	unknown	unknown	unknown
NC_014034.1\|WP_013067065.1\|1441631_1442135_+\|acetone-carboxylase-subunit-gamma	unknown	unknown	gnl\|CDD\|370171
NC_014034.1\|WP_013067063.1\|1437098_1439252_+\|hydantoinase/oxoprolinase-family-protein	unknown	unknown	gnl\|CDD\|223223
NC_014034.1\|WP_181443846.1\|1432261_1432942_-\|AAA-family-ATPase	unknown	unknown	gnl\|CDD\|273258
NC_014034.1\|WP_080514591.1\|1447195_1447495_+\|transposase	unknown	unknown	gnl\|CDD\|372671
NC_014034.1\|WP_013067061.1\|1433786_1434221_-\|transposase	unknown	unknown	unknown
NC_014034.1\|WP_013067055.1\|1425743_1427426_+\|restriction-endonuclease-subunit-S	unknown	unknown	gnl\|CDD\|341135
NC_014034.1\|WP_013067062.1\|1435178_1436972_+\|sigma-54-dependent-Fis-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|225822
NC_014034.1\|WP_013067067.1\|1443009_1443876_-\|LysR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|223656
NC_014034.1\|WP_013067053.1\|1421842_1424296_+\|DEAD/DEAH-box-helicase-family-protein	unknown	unknown	gnl\|CDD\|226581
NC_014034.1\|WP_013067058.1\|1430562_1431498_+\|hypothetical-protein	unknown	unknown	unknown
NC_014034.1\|WP_013067054.1\|1424301_1425747_+\|N-6-DNA-methylase	unknown	unknown	gnl\|CDD\|280533
NC_014034.1\|WP_013067059.1\|1431970_1432210_-\|hypothetical-protein	unknown	unknown	unknown
NC_014034.1\|WP_013067069.1\|1445070_1446105_+\|ABC-transporter-substrate-binding-protein	unknown	unknown	gnl\|CDD\|238568
NC_014034.1\|WP_013067068.1\|1443972_1444884_+\|EamA-family-transporter	unknown	unknown	gnl\|CDD\|273359
NC_014034.1\|WP_080514681.1\|1428832_1430554_+\|DUF3696-domain-containing-protein	unknown	unknown	gnl\|CDD\|227274
NC_014034.1\|WP_013067060.1\|1433439_1433790_-\|IS66-family-insertion-sequence-element-accessory-protein-TnpB	unknown	unknown	gnl\|CDD\|377551

Protein	Function_ID	Function_description	E-value
NC_014034.1\|WP_080514591.1\|1447195_1447495_+\|transposase	gnl\|CDD\|372671	pfam13683, rve_3, Integrase core domain.	1.37581e-15
NC_014034.1\|WP_013067065.1\|1441631_1442135_+\|acetone-carboxylase-subunit-gamma	gnl\|CDD\|370171	pfam08882, Acetone_carb_G, Acetone carboxylase gamma subunit. Acetone carboxylase is the key enzyme of bacterial acetone metabolism, catalyzing the condensation of acetone and CO(2) to form acetoacetate.	2.60986e-70
NC_014034.1\|WP_013067064.1\|1439266_1441576_+\|hydantoinase-B/oxoprolinase-family-protein	gnl\|CDD\|223224	COG0146, HyuB, N-methylhydantoinase B/acetone carboxylase, alpha subunit [Amino acid transport and metabolism / Secondary metabolites biosynthesis, transport, and catabolism].	2.09991e-163
NC_014034.1\|WP_181443846.1\|1432261_1432942_-\|AAA-family-ATPase	gnl\|CDD\|273258	TIGR00763, Lon_protease, endopeptidase La. This protein, the ATP-dependent serine endopeptidase La, is induced by heat shock and other stresses in E. coli, B. subtilis, and other species. The yeast member, designated PIM1, is located in the mitochondrial matrix, required for mitochondrial function, and also induced by heat shock. [Protein fate, Degradation of proteins, peptides, and glycopeptides].	5.04002e-19
NC_014034.1\|WP_013067067.1\|1443009_1443876_-\|LysR-family-transcriptional-regulator	gnl\|CDD\|223656	COG0583, LysR, Transcriptional regulator [Transcription].	3.63578e-28
NC_014034.1\|WP_013067055.1\|1425743_1427426_+\|restriction-endonuclease-subunit-S	gnl\|CDD\|341135	cd17246, RMtype1_S_SonII-TRD2-CR2_like, Type I restriction-modification system specificity (S) subunit Target Recognition Domain-ConseRved domain (TRD-CR), similar to Shewanella oneidensis MR-1 S subunit (S.SonII) TRD2-CR2. This model contains Shewanella oneidensis MR-1 S subunit (S.SonII) TRD2-CR2 and similar TRD-CR's. S.SonII recognizes 5'... GTCANNNNNNRTCA ... 3'. The restriction-modification (RM) system S subunit consists of two variable target recognition domains (TRD1 and 2) and two conserved regions (CR1 and CR2) which separate the TRDs. The TRDs each bind to different specific sequences in the DNA. RM systems protect a bacterial cell against invasion of foreign DNA by endonucleolytic cleavage of DNA that lacks a site specific modification. The host genome is protected from cleavage by methylation of specific nucleotides in the target sites. In type I systems, both restriction and modification activities are present in one enzyme complex composed of one DNA specificity (S) subunit (this family), two modification (M) subunits and two restriction (R) subunits. This model contains both TRD1-CR1 and TRD2-CR2. It may also include TRD-CR-like sequence-recognition domains of various type II restriction enzymes and methyltransferases and type I DNA methyltransferases. S.SonII TRD1-CR1 does not belong to this subfamily.	5.07362e-48
NC_014034.1\|WP_013067062.1\|1435178_1436972_+\|sigma-54-dependent-Fis-family-transcriptional-regulator	gnl\|CDD\|225822	COG3284, AcoR, Transcriptional activator of acetoin/glycerol metabolism [Secondary metabolites biosynthesis, transport, and catabolism / Transcription].	2.93757e-84
NC_014034.1\|WP_013067063.1\|1437098_1439252_+\|hydantoinase/oxoprolinase-family-protein	gnl\|CDD\|223223	COG0145, HyuA, N-methylhydantoinase A/acetone carboxylase, beta subunit [Amino acid transport and metabolism / Secondary metabolites biosynthesis, transport, and catabolism].	5.01025e-170
NC_014034.1\|WP_013067053.1\|1421842_1424296_+\|DEAD/DEAH-box-helicase-family-protein	gnl\|CDD\|226581	COG4096, HsdR, Type I site-specific restriction-modification system, R (restriction) subunit and related helicases [Defense mechanisms].	0
NC_014034.1\|WP_013067069.1\|1445070_1446105_+\|ABC-transporter-substrate-binding-protein	gnl\|CDD\|238568	cd01148, TroA_a, Metal binding protein TroA_a. These proteins are predicted to function as initial receptors in ABC transport of metal ions in eubacteria. They belong to the TroA superfamily of helical backbone metal receptor proteins that share a distinct fold and ligand binding mechanism. A typical TroA protein is comprised of two globular subdomains connected by a single helix and can bind the metal ion in the cleft between these domains.	4.9215e-78
NC_014034.1\|WP_013067054.1\|1424301_1425747_+\|N-6-DNA-methylase	gnl\|CDD\|280533	pfam02384, N6_Mtase, N-6 DNA Methylase. Restriction-modification (R-M) systems protect a bacterial cell against invasion of foreign DNA by endonucleolytic cleavage of DNA that lacks a site specific modification. The R-M system is a complex containing three polypeptides: M (this family), S (pfam01420), and R. This family consists of N-6 adenine-specific DNA methylase EC:2.1.1.72 from Type I and Type IC restriction systems. These methylases have the same sequence specificity as their corresponding restriction enzymes.	1.2126e-85
NC_014034.1\|WP_013067068.1\|1443972_1444884_+\|EamA-family-transporter	gnl\|CDD\|273359	TIGR00950, Uncharacterized_inner_membrane_transporter_YicL, Carboxylate/Amino Acid/Amine Transporter. [Transport and binding proteins, Amino acids, peptides and amines].	2.01726e-20
NC_014034.1\|WP_080514681.1\|1428832_1430554_+\|DUF3696-domain-containing-protein	gnl\|CDD\|227274	COG4938, COG4938, Uncharacterized conserved protein [Function unknown].	2.71947e-26
NC_014034.1\|WP_013067060.1\|1433439_1433790_-\|IS66-family-insertion-sequence-element-accessory-protein-TnpB	gnl\|CDD\|377551	pfam05717, TnpB_IS66, IS66 Orf2 like protein. This protein is found in insertion sequences related to IS66. The function of these proteins is uncertain, but they are probably essential for transposition.	3.0727e-47

>NC_014034.1|WP_013067061.1|1433786_1434221_-|transposase
MLDEKEGGDVVVWGIPVITADNGRRVWPDEIKAMAVKKIEAGTKIVTVAKEIGANESLVAKWARAELPELPRRGRPQGKAASQGKSPQFVEVMVPSEPARQAKQKGAADAAACQIRIGDAEISLRGDFPAEQLAEILRAVRASQ
>NC_014034.1|WP_013067060.1|1433439_1433790_-|IS66-family-insertion-sequence-element-accessory-protein-TnpB
MSYHTPSYRIYLATEPIDFRKGMDGLVAHVASQFQLDPFDGAIWVFRSRRADKLKMIVWDGTGLVLTMKRLDGKRFVWPKAQSGPMMLNQVQFDALFAGIDWRGIAVNAPRKPVIA
>NC_014034.1|WP_181443846.1|1432261_1432942_-|AAA-family-ATPase
MRKSVREGWPGVRLPPLLLDGPPGIAKSTWARHLATALRMPSMSVEATVENASFGVLGCQRGWATAGPGRLLQLILQERVGNPIVVIDELEKAGRVTGTNGGSYDLCGGLLPLLESATASRWTCPYFQVPFDLGQVSWVMTVNATRPLPEPLLSRCPPIRLPQLTTRDLTGFARRQGARRALSDDSIEVIVEAIQASATPAQPISLRTVMRMISRAETLEAGPQWH
>NC_014034.1|WP_013067059.1|1431970_1432210_-|hypothetical-protein
MAFLFEDRARQKAEARARDEDRLARGEISAADLQKENAHFARALSGQNGPFRVGFPVKSQPGKRRYVEFPPNKVRKDDS
>NC_014034.1|WP_013067058.1|1430562_1431498_+|hypothetical-protein
MSVFLDPNIYCYSIDEWQQGAALDRMHHLTTFLESLGIEEERLEARNQVELWLSEILIFATYEMNPNINTPPNGFYFRQYVSGLLPALMRRKITFEAPAVDACRASERINIDNCVIEEALICALDEISTDDAKKITYIFASSRVSLALGGGVFSAEFEINEVNGRHFLDECDLFPLSSKVSPDIAIVAAAEVLKDKLSIEDATWREHSVCKAILHENFLPSITRADFGADERIYHSRVVYSLLQILSGRNCTINEHSMNPEKIWFDKKWHGKWNSYVFRNGPSDIDSRCSRIYYAKVDGGVLLYEYNGDAH
>NC_014034.1|WP_080514681.1|1428832_1430554_+|DUF3696-domain-containing-protein
MKIKYRINNFKAFSDSGEMSFSPVTVLCGANSTGKSSIIKSILLAKQSTAERRSSLKIDAPSQPLILNGELTKLGAWSDTITGKDRAKSMGFCWSVKLSQEEFDDALKRAGLLRRGEASSELDLANQRDLTLSVSLSSDTEVREELSARVDRWDVNLDDLNVRVFRQEVANGSRPLYRVEINSIRKLIRRKGSKFGSYRVILGDLHKALSGADTPISLGNVYAVNSGPFIGRIEPRFDETWTNFFEAIYKLSVSHRGRKRGPAPGWLEDLGAAVRTYRKGLSEGKMPTARNTAMRVLTYLAIEFVSEISLVFSETKAVLAPMWQDIRYLGPLRDQPRRYYQFDDTGGADVGVSGEFTVQVLALEQGRVLQSTRLASLPSNRIKFTDRKLTTLLDHTNFWLSWMGLPAVSPLNLQQSLYGLAVGDLRVGLLDVGFGVSQVLPIIVETLRAEKGDLVILEQPEIHLHPRVQALLGDFLLARSQDGVRFLVESHSEYLIKRLCRRVSESESENLRPSIEILFIEGSPEGASCRPVELNDYGEILNWPKGFFDLDEDLHWTHAALERRRASNAKKQK
>NC_014034.1|WP_013067056.1|1427422_1428361_+|hypothetical-protein
MTTLPKGKSLWIRSFYGFNPEEDGYAGWTKEAGRDHILKHIKGGDLILIYGAGSKETDKALRSYVLGFLQVDATPIDDRDKASPESLKRKAAQGWANKWTFGIPVRRAWRVDEKLLIRSIAFNTYRPEAGQAIGVWGAALEPEEIEKALKIRVTEVNVFGEPPIAATGLKKAPLGDEFKPSRGFPGAFGTHTSTKNDGETWLYLFRFEGDCHALVGRPKAHGGKSLAWKIGVSSDTAARLGQLNLGIPPAAKGRWGQFLQARFPDRRSAEAAEQRFKDESNGKLESLGGEFFWGDEMQAMLLFAGIPGVSRF
>NC_014034.1|WP_013067055.1|1425743_1427426_+|restriction-endonuclease-subunit-S
MNADQLLRLYDRVCEAEDAVPRLRRFVLDLAVRGKLVPQDPDDEPASELLKRIEKEKARLVNTGEIRKPKSQTPLNGDVCPFLVPRGWALTRLGSVIDLLSGQHLQPNEYSSNPAAGIPYITGPSDFAEVGLSISRYALVRKAVARGGQLLLTVKGSGVGKTTICDLPEVAISRQLMSLAPILWSIRFLEIITHRLADTLQEQARSLIPGISREDVADFAFPLPPLAEQHRIVAKVEELMALLDRIEAARAGREEGRNRLTAATLARLTDPKADAPAAARFALDTLAPLTTRPDQIKTLRQTILNLAVRGKLVPQDPADEPASELLKRFKAAKIAHKWETGDARNKLAPDAEVSSYPLELPKGWAVQSFENLFLFIDYRGNTPPKTDSGVPLITAKNVRMGSLNREPREFISEKTFKSWMTRGFPKLGDLFFTTEAPLANVCLNDIQEPFALAQRVICLQPYAEISTHYLMLALCGDVMQSLIDGQATGMTAKGIKASKLKPLPISLPPLAEQHRIVAKVDALMRLLDALEAALSASATTRARLLDATLRAALTDTGEAA
>NC_014034.1|WP_013067054.1|1424301_1425747_+|N-6-DNA-methylase
MSVRTLVKSLQQIMWKDTGVDGDAQRLSQMCWMFFLKIVDDQDEALELTRDDYTSPIPADLQWRAWAADPEGMTGDQLLSFVNEELFPGLKGLRPATPRARTIRDVFEDAYNFMKSGQLLRQVINKINEIDFNNLSERQHFGDIYEQLLNDLQNAGNAGEYYTPRAVTAFMVERIDPRPGEIVMDPACGTGGFLTCAMRHMRARHIRLPEHEDAMQRSLRAVEKKPLPHMLCVTNMLLNGIEEPHFVRHDNTLARPLTSWTRDERVDIVLTNPPFGGKEEDGIENNFPTFRTRETADLFLALIIRLLKPGGRAAVVLPDGSLFGEGIKTRLKEHLMAECNLHTIVRLPNSVFKPYASIGTNLLFFEKGTPTTETWFWEHRVPEGQKAYSMTKPIRLDHLAGCADWWGGATREGRVEGPQAWKVSAEEIKARGYNLDIKNPHAEAEDLGDPEHLLAALDEAEAEVTRLRAALKEILTEALAR
>NC_014034.1|WP_013067053.1|1421842_1424296_+|DEAD/DEAH-box-helicase-family-protein
MDKNGLSERDICSIFITPALQKAGWDPVTQIREEVGFTRGRINVRGKLVSRGQGKRADYILSIRPNIRLAVIEAKDNAHATGAGMQQALDYAETLNLPFAFSSNGDGFLFHDRTGMSPTPEVLLSLDDFPSPTELWARYCAWKGLDAAASSVALQDYHDDGSGKEPRYYQINAVNAAMEAIGRGENRVLLVMATGTGKTYTAFQIIWRYRQAFPGKRILFLADRNVLIDQTMVNDFRPFSGKMAKLSTQSKTIERADGSSVELPLGLDRKRRIDPSYEIYLGLYQAITGPAEEDKIFREFSQDFFDLIIIDECHRGSAAEDSAWREILDHFSGAVQIGMTATPKETEYASNIAYFGAPAYSYTLRQGIRDGFLAPYKVIKVHIDRDIQGYRPEAGQTDRDGALVEDRIYNTKDFDRTLVLDDRTKLVARKVTEFLKESGDRMAKTIVFCVDQEHAARMRQALVNENADLVAQNPRYVMRITGSDTEGLEQLGNFIDPEVSHPVIVTTSRLLSTGVDAQTCRLIVLDREVGSMTEFKQIVGRGTRVHEDTGKLYFTLMDFRGATNHFADPDFDGEPVQIYTPTGTDPIVPPDDVPPPEGDEPPLSATPGPDETVLIDPVATLGQTGSGAPQRKIYVDGVAATIVAERVEYLDEHGRLITESLRDYTRKALKRRFASLDDFLKRWKTPEKKQAVLDELAAEGLPLDLVAAELGRDLDPFDLICHIAFDAKPLTRRERAEGVKKRDVWARYGATARAVLTALLDKYADDGLLDFDDPKILKINPFSQMGTEVELIRAFGKKQDYLKAMHDLQAALYDESA
>NC_014034.1|WP_013067062.1|1435178_1436972_+|sigma-54-dependent-Fis-family-transcriptional-regulator
MAHRIRKRGWEEFMAVGRASPDVRSEVLQSWQRSAGRRIEKLKQAPLLSEEDLLTQRAQARRLRSGARGVLNRAGSLLGGSENILLLCDRGGVVLDAVGDETTLARGRENHLHLGGHWTEDAIGTNAIGTAIALARPVELRDAEHFCEEIHRWNCAATPITDQSTGLLLGVMDISWPSDLTQASAMALSAALALQVESELIRLLAREREFLMEQLHLRRLRRGNEPMLIMDRSGADVFATENFVRFCDDDKALRRLRERIPNLIDQAPDTISEALAGCLPGTDMEVIETGSDAIGVLISLRRNRLHAGESCPDLVRIGAAGAVSATLSAQAKRLAQTAIPLLVEGETGTGKTHLARAIHRASLQSGGPFELIDCARLTAAPLREDMLEGRIGADDGVLCLNRPEEASPEVQKLLLNLIEDVSGAGMRIIALATRPLYKEMQKGAFRSDLYYRLAGAKLEIRPLRERRDEIAPLLSELVRNHMADRGGRELKFTSGAMAALIAHAWPGNLLEMTHLIATLDALSPTGLIDVRSLPPEFRHSGGGSGEETLRDKERQEILGAIEVENGNLTRAARRLGIARSTLYLKLESYGLPRPRKT
>NC_014034.1|WP_013067063.1|1437098_1439252_+|hydantoinase/oxoprolinase-family-protein
MPLDREKTRSVQVLGIDAGGTMTDTFFVDANGDFVVGKAQSTPQNEALGLLESSREGLQHWGLSLEEALSSIQTGVYSGTAMLNRVVQRKGLRCGLIVNAGMEDFHRMGRAIQAYLGFAYEDRIHLNTHYYDEPLVPRHLTRGVMERIDMFGDVVIPLREETARQAAAELIAQDVEGIVISLLHSYKNPAHERRVRDIVAEELEKAGKTTPVFASTDYYPVRKETHRTNTTILEAYAAEPSRQTLRKITGAFKENGSRFDFRVMATHGGTISWKAKELARTIVSGPIGGVIGAKYLGEVLGYKNIACSDIGGTSFDVALITQNELTIRNDPDMARLVLSLPLVAMDSVGAGAGSFIRLDPYTKAIKLGPDSAGYRVGVCWAESGIETVTISDCHVILGYLNPDNFLGGQVKLDRQRAWDAMKTQIADPLGLSVEDAAAGVIELLDSDLRDYLRSMISGKGYSPSSFTCFSYGGAGPVHTYGYTEGLGFEDVIVPAWAAGFSAFGCAAADFEYRYDKSLDLNIARDGSDDLKAHEARTLNDAWHELTERVLEEFELNGYTRDQVKLQPGFRMQYRGQLNDLEIESPIPAAKTAADWDKLVAAFNDTYGRVYAASARSPELGYSVTGAIMRGMVPIPKPKIPKEPETGATPPEAAKLGTRKFYRKKKWVDARLYRMEKLLPGNRITGPAIIESDATTFVVPDGFETWLDGHRLFHLKEV
>NC_014034.1|WP_013067064.1|1439266_1441576_+|hydantoinase-B/oxoprolinase-family-protein
MNAPTAIRGIVRGGDTLKQHRDGIMEASKRTGHYAGLKQMELRDSDPIMYNKLFSRLRAGVVDARETAKKIAASPIVEQEGELCFTLYNAAGDSILTSTGIIIHVGTMGAAIKYMIENDWESNPGVKDRDIFCNNDSLIGNVHPCDIHTIVPIFHEGELIGWVGGVTHVIDTGAVGPGSMTTGQVQRFGDGYSVTCRKVGENDTLFRDWLHESQRSVRTTRYWMLDERTRIAGCHMIRKLVAEVIAEEGIEAYWKFAYEAVEHGRLGLQNRIKAMTIPGKYRQVGFVDVPYAHDDVRVPSDFAKVDTIMHTPSEMTIRPDGTWRLDFEGASRWGWHTYNAHSVSFTSGIWVMMTQTLIPTEMINDGAAYGTEFRLPKGTWMNPDDRRVAFAYSWHFLVSSWTALWRGLSRSYFGRGYLEEVNAGNANTSNWLQGGGFNQYDEIHAVNSFECAANGVGASAIGDGLSHAAAIWNPEGDMGDMEIWELAEPLVYLGRQIKASSGGAGKYRGGCGFESLRMVWNAKDWTMFFMGNGHISSDWGLMGGYPAASGYRFEAHETGLKEIIAQGGDIPHGGDTDPGNPVWDGLLKGARIKRDKQAITTEAMFKDYDLYLNYMRGGPGFGDPLDRDPGAVAADVNGGYLVERFAQSVYGVVLVKGADGLLAADAAATEARRAAIRKDRLAKAVPTAEWMKGERDRILKKEAGVHVQQMFAASFKLGPKWEEGFRKFWDLPIDWRLMEADLPIPSYGRDYSMDLSELPDVKTVQFVEE
>NC_014034.1|WP_013067065.1|1441631_1442135_+|acetone-carboxylase-subunit-gamma
MAYTKAKIKDLVDGKIDRDTLHTMLATPKDADRFVMYLEVLQDQVPWEDRIILPLGPKLYIVQRKSDHKWVVKSHAGHEFCDWRENWKLHAVMRVRETPEAMEEIYPRLMAPTAGWQVIREYYCPLSGDLLDVEAPTPWYPVIHDFEPDIDAFYSEWLGLKIPERAA
>NC_014034.1|WP_023911249.1|1442287_1442503_+|hypothetical-protein
MQVLICMNQSDLPHDLSGQIAVIPEAEEIAAQFRAALARKGVSQRDLSARAGVNAGREFRLCGRFGRICPG
>NC_014034.1|WP_115503939.1|1442582_1442903_+|hypothetical-protein
MLRFSLAGVQLKFSAVHAAGGGLTIPASGIGGNWIVKLRQRRRSVGNAIIAAFNDAAQNAPRSARRKFHNTLNINNYQFLRSVYGGHCFRQPSAASICDCDCQSIA
>NC_014034.1|WP_013067067.1|1443009_1443876_-|LysR-family-transcriptional-regulator
MEPQNWDDIRLFLALAREGTLQGAARRLGLGVATISRRIDRMEATLGLPLFLRRQTGHELTDQGAALLPRAEAMELALQEMRREAGAQVEIRGLVRLASIESLVAPVVLPALGPLLAANPGLDVEVHWGTATVNLHRHDADLALRMVPPERGNLTVRRLAQMGFGLYGPAEGAPPARHVTWPDAPSLAVPLAWSAAFGARTAPRLALNTLTAQVQAVRDGLGVAVLPHFLAREAGLRLLAARLPDGAPMERPILLATHAELAASRRVRAVAAAIADHVLAKRHDLEGA
>NC_014034.1|WP_013067068.1|1443972_1444884_+|EamA-family-transporter
MSDVFSAPRPRAETAAFALSALAAVFWGSNFEATRVVLQEMPPWTAAAGRFLIAALAILGWLWLAEGSGLPALRRNWKVFLGLGVVGVAGFNAALFLGMRSSSPVTAALIMGTSPLTTTLIEAALTRRWPKAGTLAGMAISLVGVALTVGAFSGARLAPGDGLILLGSLAWALYTVGCRRWVVAASPLETSVWTMLAGALALLGAAFALETPVASVLAASPAAWGATLWMALAGSVLAYLFWQVGIQIRGPGATSVLFNLVPVSALAIAALFGRTPELSQLAGVALAILGVLLASGRLTVPRR
>NC_014034.1|WP_013067069.1|1445070_1446105_+|ABC-transporter-substrate-binding-protein
MLPLKTAILGGVALSCLCSAALAERTSYPLTIENCEQKVTFAKAPERTVALGQNSAEILLLLGLEDRMAATAFWPNSVLPELAAAHDKVEVLTVEFPTLEAVLAQQPDFVPAMLVTLMGPDSKVTKREDLEALGIPTYLSPSACTTEADTQSANGSAASSAYGVRKDLWSMDLLYKEIEDMARIFDVAERGAAVIADFKAREAALRAEFAPREDLTFLFWFSSPSPADDAYLGGGHGPSGYIADLLGGSNAIRTEAEWPTLGWEGIMAANPTVFVAAQVDRNRWDLDRADTKIAWLTSDPAVSQMEAVKAGRIAVMSGAAMNPSIRTLYGAEQLADQLRSFDLP
>NC_014034.1|WP_080514591.1|1447195_1447495_+|transposase
MRLWKLKPWPRHQPKSASGKPGAGHIFTRPHTPKTNGRAERFIQTLLREWAYGLVHPSAQARNTDLPRWLDWFNTSRPHSALNGLSPVKRVNNLMRTHS

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Crispr_ID: NC_014034_7

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_014034_7

2157729-2158039

TypeVI-A

Consensus_repeat	Method
GGTTCAGTCCGCCGTCGTCTTGGCGGTGATGTGA	CRISPRCasFinder
GGTTCAGTCCGCCGTCGTCTTGGCGGTGATGTGAGGC	CRT
GGTTCAGTCCGCCGTCGTCTTGGCGGTGATGTGAGGC	PILER-CR

4 spacers

cas13a

The CRISPR arrays of NC_014034_7

>merge|NC_014034|7|2157729-2158039|CRISPRCasFinder,CRT,PILER-CR
TTGGGTTCCCGCCGTCATCTTGGCGGTGATGTGAGGCTTACCCCATACCCAAGAAAGGAACATCATGGGTTCAGTCCGCCGTCGTCTTGGCGGTGATGTGAGGCTCTCCCAGCATACCAAACCGCTGGCGACCATCAGGTTCAGTCCGCCGTCGTCTTGGCGGTGATGTGATGCACAGGAGAGACCGATGAAAATCACGGCCTTCGGTTCAGTCCGCCGTCGTCTTGGCGGTGACGTGAGGCACCTAAACAAGAGGTTCTACGATGCCGAAAGGGGTTCAGTCCGCCGTCGTCTTGGCGGTGATGTGAGGC

>NC_014034|7|6|2157729-2158036|CRISPRCasFinder
TTGGGTTCCCGCCGTCATCTTGGCGGTGATGTGA	GGCTTACCCCATACCCAAGAAAGGAACATCATG
GGTTCAGTCCGCCGTCGTCTTGGCGGTGATGTGA	GGCTCTCCCAGCATACCAAACCGCTGGCGACCATCA
GGTTCAGTCCGCCGTCGTCTTGGCGGTGATGTGA	TGCACAGGAGAGACCGATGAAAATCACGGCCTTC
GGTTCAGTCCGCCGTCGTCTTGGCGGTGACGTGA	GGCACCTAAACAAGAGGTTCTACGATGCCGAAAGG
GGTTCAGTCCGCCGTCGTCTTGGCGGTGATGTGA

>NC_014034|7|5|2157729-2158039|CRT
TTGGGTTCCCGCCGTCATCTTGGCGGTGATGTGAGGC	TTACCCCATACCCAAGAAAGGAACATCATG
GGTTCAGTCCGCCGTCGTCTTGGCGGTGATGTGAGGC	TCTCCCAGCATACCAAACCGCTGGCGACCATCA
GGTTCAGTCCGCCGTCGTCTTGGCGGTGATGTGATGC	ACAGGAGAGACCGATGAAAATCACGGCCTTC
GGTTCAGTCCGCCGTCGTCTTGGCGGTGACGTGAGGC	ACCTAAACAAGAGGTTCTACGATGCCGAAAGG
GGTTCAGTCCGCCGTCGTCTTGGCGGTGATGTGAGGC

>NC_014034|7|7|2157796-2158039|PILER-CR
GGTTCAGTCCGCCGTCGTCTTGGCGGTGATGTGAGGC	TCTCCCAGCATACCAAACCGCTGGCGACCATCA
GGTTCAGTCCGCCGTCGTCTTGGCGGTGATGTGATGC	ACAGGAGAGACCGATGAAAATCACGGCCTTCGGT
TCAGTCCGCCGTCGTCTTGGCGGTGACGTGAGGCACC	TAAACAAGAGGTTCTACGATGCCGAAAGGGGT
TCAGTCCGCCGTCGTCTTGGCGGTGATGTGAGGC

Protein	Signature genes	Signature genes Name	Protein_function
NC_014034.1\|WP_013067718.1\|2149834_2150071_+\|hypothetical-protein	unknown	unknown	unknown
NC_014034.1\|WP_013067728.1\|2158409_2162267_+\|hypothetical-protein	cas13a	cas13a_c2c2_CAS-VI-A	unknown
NC_014034.1\|WP_013067723.1\|2155435_2155756_+\|phage-holin-family-protein	unknown	unknown	gnl\|CDD\|374352
NC_014034.1\|WP_013067722.1\|2154879_2155374_+\|DUF4376-domain-containing-protein	unknown	unknown	gnl\|CDD\|373004
NC_014034.1\|WP_013067731.1\|2166078_2167413_+\|trigger-factor	unknown	unknown	gnl\|CDD\|234956
NC_014034.1\|WP_013067724.1\|2155757_2156432_+\|TIGR02594-family-protein	unknown	unknown	gnl\|CDD\|131643
NC_014034.1\|WP_013067725.1\|2156450_2156798_+\|hypothetical-protein	unknown	unknown	unknown
NC_014034.1\|WP_013067720.1\|2152997_2153936_+\|hypothetical-protein	unknown	unknown	unknown
NC_014034.1\|WP_013067719.1\|2150121_2153001_+\|phage-membrane-protein	unknown	unknown	unknown
NC_014034.1\|WP_013067733.1\|2168533_2168761_-\|30S-ribosomal-protein-S18	unknown	unknown	gnl\|CDD\|178997
NC_014034.1\|WP_013067737.1\|2170556_2171942_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|236545
NC_014034.1\|WP_023911505.1\|2156966_2157368_+\|DNA-adenine-methylase	unknown	unknown	gnl\|CDD\|366913
NC_014034.1\|WP_013067727.1\|2157352_2157628_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|275209
NC_014034.1\|WP_013067721.1\|2153935_2154880_+\|hypothetical-protein	unknown	unknown	unknown
NC_014034.1\|WP_013067736.1\|2169592_2170483_-\|DMT-family-transporter	unknown	unknown	gnl\|CDD\|307170
NC_014034.1\|WP_013067729.1\|2162723_2164274_+\|hypothetical-protein	unknown	unknown	unknown
NC_014034.1\|WP_013067734.1\|2168778_2169213_-\|30S-ribosomal-protein-S6	unknown	unknown	gnl\|CDD\|179034
NC_014034.1\|WP_013067730.1\|2164486_2165695_-\|site-specific-integrase	unknown	unknown	gnl\|CDD\|271182
NC_014034.1\|WP_013067732.1\|2167948_2168521_-\|50S-ribosomal-protein-L9	unknown	unknown	gnl\|CDD\|234659
NC_014034.1\|WP_013067738.1\|2172080_2173478_-\|aldehyde-dehydrogenase-family-protein	unknown	unknown	gnl\|CDD\|143452

Protein	Function_ID	Function_description	E-value
NC_014034.1\|WP_013067731.1\|2166078_2167413_+\|trigger-factor	gnl\|CDD\|234956	PRK01490, tig, trigger factor; Provisional.	6.15393e-152
NC_014034.1\|WP_013067723.1\|2155435_2155756_+\|phage-holin-family-protein	gnl\|CDD\|374352	pfam16083, Phage_holin_3_3, LydA holin phage, holin superfamily III. Phage_holin_3_3 is a family of small hydrophobic holin proteins with one or more transmembrane domains. Holins are encoded within the genomes of Gram-positive and Gram-negative bacteria as well as those of the bacteriophages of these organisms. Their primary function appears to be transport of murein hydrolases across the cytoplasmic membrane to the cell wall where these enzymes hydrolyze the cell wall polymer as a prelude to cell lysis. When chromosomally encoded, these enzymes are therefore autolysins. Holins may also facilitate leakage of electrolytes and nutrients from the cell cytoplasm, thereby promoting cell death. Some may catalyze export of nucleases. LydA and lydB are encoded on the dar operon. The phenotype of a rapid lysis in the absence of active LydB suggests that this protein might be an antagonist of the holin LydA.	2.42864e-13
NC_014034.1\|WP_013067722.1\|2154879_2155374_+\|DUF4376-domain-containing-protein	gnl\|CDD\|373004	pfam14301, DUF4376, Domain of unknown function (DUF4376). This domain family is found in bacteria and viruses, and is approximately 110 amino acids in length.	1.01392e-26
NC_014034.1\|WP_013067724.1\|2155757_2156432_+\|TIGR02594-family-protein	gnl\|CDD\|131643	TIGR02594, hypothetical_protein, TIGR02594 family protein. Members of this protein family known so far are restricted to the bacteria, and for the most to the proteobacteria. The function is unknown.	2.46865e-18
NC_014034.1\|WP_013067734.1\|2168778_2169213_-\|30S-ribosomal-protein-S6	gnl\|CDD\|179034	PRK00453, rpsF, 30S ribosomal protein S6; Reviewed.	5.176e-47
NC_014034.1\|WP_013067730.1\|2164486_2165695_-\|site-specific-integrase	gnl\|CDD\|271182	cd00801, INT_P4_C, Bacteriophage P4 integrase, C-terminal catalytic domain. P4-like integrases are found in temperate bacteriophages, integrative plasmids, pathogenicity and symbiosis islands, and other mobile genetic elements. The P4 integrase mediates integrative and excisive site-specific recombination between two sites, called attachment sites, located on the phage genome and the bacterial chromosome. The phage attachment site is often found adjacent to the integrase gene, while the host attachment sites are typically situated near tRNA genes. This family belongs to the superfamily of DNA breaking-rejoining enzymes, which share the same fold in their catalytic domain and the overall reaction mechanism. The catalytic domain contains six conserved active site residues. Their overall reaction mechanism involves cleavage of a single strand of a DNA duplex by nucleophilic attack of a conserved tyrosine to give a 3' phosphotyrosyl protein-DNA adduct. In the second rejoining step, a terminal 5' hydroxyl attacks the covalent adduct to release the enzyme and generate duplex DNA.	3.74385e-42
NC_014034.1\|WP_013067737.1\|2170556_2171942_-\|hypothetical-protein	gnl\|CDD\|236545	PRK09510, tolA, cell envelope integrity inner membrane protein TolA; Provisional.	2.4471e-09
NC_014034.1\|WP_023911505.1\|2156966_2157368_+\|DNA-adenine-methylase	gnl\|CDD\|366913	pfam02086, MethyltransfD12, D12 class N6 adenine-specific DNA methyltransferase.	1.88942e-11
NC_014034.1\|WP_013067727.1\|2157352_2157628_-\|hypothetical-protein	gnl\|CDD\|275209	TIGR04416, hypothetical_protein, group II intron reverse transcriptase/maturase. Members of this protein family are multifunctional proteins encoded in most examples of bacterial group II introns. These group II introns are mobile selfish genetic elements, often with multiple highly identical copies per genome. Member proteins have an N-terminal reverse transcriptase (RNA-directed DNA polymerase) domain (pfam00078) followed by an RNA-binding maturase domain (pfam08388). Some members of this family may have an additional C-terminal DNA endonuclease domain that this model does not cover. A region of the group II intron ribozyme structure should be detectable nearby on the genome by Rfam model RF00029. [Mobile and extrachromosomal element functions, Other].	3.41748e-19
NC_014034.1\|WP_013067733.1\|2168533_2168761_-\|30S-ribosomal-protein-S18	gnl\|CDD\|178997	PRK00391, rpsR, 30S ribosomal protein S18; Reviewed.	5.77485e-37
NC_014034.1\|WP_013067736.1\|2169592_2170483_-\|DMT-family-transporter	gnl\|CDD\|307170	pfam00892, EamA, EamA-like transporter family. This family includes many hypothetical membrane proteins of unknown function. Many of the proteins contain two copies of the aligned region. The family used to be known as DUF6. Members of this family usually carry 5+5 transmembrane domains, and this domain attempts to model five of these.	4.47803e-15
NC_014034.1\|WP_013067732.1\|2167948_2168521_-\|50S-ribosomal-protein-L9	gnl\|CDD\|234659	PRK00137, rplI, 50S ribosomal protein L9; Reviewed.	3.28408e-69
NC_014034.1\|WP_013067738.1\|2172080_2173478_-\|aldehyde-dehydrogenase-family-protein	gnl\|CDD\|143452	cd07134, ALDH_AlkH-like, Pseudomonas putida Aldehyde dehydrogenase AlkH-like. Aldehyde dehydrogenase AlkH (locus name P12693, EC=1.2.1.3) of the alkBFGHJKL operon that allows Pseudomonas putida to metabolize alkanes and the aldehyde dehydrogenase AldX of Bacillus subtilis (locus P46329, EC=1.2.1.3), and similar sequences, are present in this CD.	0

>NC_014034.1|WP_013067727.1|2157352_2157628_-|hypothetical-protein
MDLFFKATEYETLQASWLKVQQNGGAAGGDGVTIATFAQGATASLRDLALALRAGGWQQGPCRRVDIPKRKGGTRRLMIPPIADRIIHGTA
>NC_014034.1|WP_023911505.1|2156966_2157368_+|DNA-adenine-methylase
MMESMIPVAPVAPAAPWLGGKRNLAKRICTILDETPCRTYCEPFVGMGGIFLRRRARPRAEVINDAGRDIANLFRILQRHYPQFLEILRFQLTVRSEFERLLATRPDTLTDLERRIQDRLQRFGDCPMNYAVP
>NC_014034.1|WP_013067725.1|2156450_2156798_+|hypothetical-protein
MTDTLLATILAQIVLPILATITTALIGWAAAKLRARWGIEIEAAQREALHQALMTGAQLALTRRGRRDDGRDLDLLARDAVAYAQTSVPDAIQALAPRDGVLKNLAAAKIAALSR
>NC_014034.1|WP_013067724.1|2155757_2156432_+|TIGR02594-family-protein
MTTDWRAAQLRLRALGFEPGPIDGLCGPKTKAAITAFGRSRGLSAEPGFGPVIAALMGADAPCPDLPWMAEALRLKGLHERRDTTRLRAWLDPAAGAIDPRAMPWCGAFVASCLRAALPGVILPDTPLAARAWSRFGDPVAPVFGAVLVFWRGAPSGWQGHVGFCRGEDAGAYHVLGGNQSDAVTVTRIAKTRLLAARWPAGVPVTGRPVRLTTKGLALSSNEA
>NC_014034.1|WP_013067723.1|2155435_2155756_+|phage-holin-family-protein
MSDARGLVELVDAIWGGAVTTMAAALAGRLMWHSTEVRARKRRFLSRELLWELPVAVGMAIIGEAVAAYFELGRTVTTGVVATLAYLGPRGAQVALTRVFFHNKES
>NC_014034.1|WP_013067722.1|2154879_2155374_+|DUF4376-domain-containing-protein
MEHGFFHPAHGYWQTTGTPTPEIRAAYPEGTVEVPLRPGADHLWTGEGWEPAPARLSVDQALANLKAARDAAIARGIEVDGLRLQTDDLSQSRLTAAALAAQLDPTLTLRWKLATGEFVALSAPQIIALALAVRAHVQACFDREADLAAQIRAAADPAAVALTF
>NC_014034.1|WP_013067721.1|2153935_2154880_+|hypothetical-protein
MAKPAKPTVPPPPLRSNPETFSARMEASLLFWKTFAEYLDALGDHAETQADAALAAALAAGAGTGLALRGNGGKLMAVNAGATALEFLTASGAGKAILANASAAGLALASDADAAAQRATLGLGTVTALAEAVTDLSAITRSGWNRFAAAQTANTPFATGAGMVLTIFYDGSAAVQLVWGHNKGESDTGQWIRWRAASTWGGWVRLHGSQTEINGLIGALALGVAQSWQDVTAARLAGTNYQNTTGRPIAVSITTGGTTANTALYLGVATPANILIAATGTGSTLRIMSHQAIVPAGHYYRFEGAAPATWAELR
>NC_014034.1|WP_013067720.1|2152997_2153936_+|hypothetical-protein
MKILTPIAVTDATLISCSIPETDFPRWNAQTTYPRGAFVISPATHTVYRALQGDNTGHDPDLEQAALADPLIDDPDPVFWQVIGATNRWRLFDGKPSVLARAAEIIRVTLAPGVAVGGVAGFGISAAEIRVTMTDAGAVVYRRAIAMQDETVVSDGLGYYVEPITELSEFVLTDLPPYAAAQITIEAIRRGGQVSVGQIVLGPVWALGRPVIGGTGFQGVDFSYVKQDDYGDLTTVRRAATRLSTFETCLPNARLLGFDTRMRSLRGGTAAVWIGSDDPRKAAINYGFYRSYRAAYQTDAWSLISIEVQGIV
>NC_014034.1|WP_013067719.1|2150121_2153001_+|phage-membrane-protein
MSASAVIGALRVNLGLDSASFQKGVARSTASLGTLKGAAMAASAAVSAIGAAIGGPALAAIVTAAARSAREITRLSQVAGASAQELQHWSFGARTVGIEQEKLADILKDVNDKVGDYLSTGGGAMADFFEKIAPRVGVTAQAFRDLSGPQALQLYVSSLEKAGLSQAEMTFYMEAIASDSTLLLPLLRANGAEMARLGESASSFGAVLGTDAITALRAAERALDDISVVLEATRNRIAADLAPAVEAMARAFVNAMREGGFLRGVIDGLMAALPHLTAYAAAFTAGLIAWQAAAIAARLATMALSVSMAGLRAAIAATGVGVLVVAMGELGLAILDAVRKAGGFAAAWYKLKAKFFEVLRDMAGGWVEFTWALADGMNDLFGTRLMGADAGITQTLRDLQIGAEDAAAAAQEVATAATEAEVTLTGLGSAGSGAGKKLKKGLTEAQKAAQEFADALRDGFRSSVEGAVDWMLDGFQGGFKGLVSLARDALKQVVALFLKNRITLSLGLGVSGGAATGAAAGAAVSGAAAGGFAGPLGLLGTAGSFLGAIGSGAAGLGTALFGAGGGLGAAGTYLSSVVGSATSSLGPFGAAIGAALPILAGVGVVFSFFKKKVTQLDAGLRLTVTDMDTLVETFSKTKTSRFWGLSKKTRETFTEAGAAIADPIEAAVAGIVGGVADMADTLGIAGRDALKGFSTQIKISTHGLSDSEAQEAIRAGFTQLSDELARMILAAGEGVSGNLSAFTSAFARRGESASETLTRLSSALATANAWLDRLGKTAYDTSLAGADAASKWAGAFGGLEAMSEAVGSYYAGFYSPAERLAQAREELSQALAGLGIDALPGSRQAFRQLIDAAFASGDSDLAAKLIQLAPAMAEITDQAQALTAALKDLDTQSLYRSGAEALYAATSEGHRRRLTGADATVQGLLAEVVRAIREGDINNARLTARLLAVQERMSLDPAR
>NC_014034.1|WP_013067718.1|2149834_2150071_+|hypothetical-protein
MILRGAAAQRRAEIETARALNHQLAGLVAFAVHDPQHLPEFRPDDTAAATAATAQGAREVDHERVRGALIAMALRPGP
>NC_014034.1|WP_013067728.1|2158409_2162267_+|hypothetical-protein
MQIGKVQGRTISEFGDPAGGLKRKISTDGKNRKELPAHLSSDPKALIGQWISGIDKIYRKPDSRKSDGKAIHSPTPSKMQFDARDDLGEAFWKLVSEAGLAQDSDYDQFKRRLHPYGDKFQPADSGAKLKFEADPPEPQAFHGRWYGAMSKRGNDAKELAAALYEHLHVDEKRIDGQPKRNPKTDKFAPGLVVARALGIESSVLPRGMARLARNWGEEEIQTYFVVDVAASVKEVAKAAVSAAQAFDPPRQVSGRSLSPKVGFALAEHLERVTGSKRCSFDPAAGPSVLALHDEVKKTYKRLCARGKNAARAFPADKTELLALMRHTHENRVRNQMVRMGRVSEYRGQQAGDLAQSHYWTSAGQTEIKESEIFVRLWVGAFALAGRSMKAWIDPMGKIVNTEKNDRDLTAAVNIRQVISNKEMVAEAMARRGIYFGETPELDRLGAEGNEGFVFALLRYLRGCRNQTFHLGARAGFLKEIRKELEKTRWGKAKEAEHVVLTDKTVAAIRAIIDNDAKALGARLLADLSGAFVAHYASKEHFSTLYSEIVKAVKDAPEVSSGLPRLKLLLKRADGVRGYVHGLRDTRKHAFATKLPPPPAPRELDDPATKARYIALLRLYDGPFRAYASGITGTALAGPAARAKEAATALAQSVNVTKAYSDVMEGRTSRLRPPNDGETLREYLSALTGETATEFRVQIGYESDSENARKQAEFIENYRRDMLAFMFEDYIRAKGFDWILKIEPGATAMTRAPVLPEPIDTRGQYEHWQAALYLVMHFVPASDVSNLLHQLRKWEALQGKYELVQDGDATDQADARREALDLVKRFRDVLVLFLKTGEARFEGRAAPFDLKPFRALFANPATFDRLFMATPTTARPAEDDPEGDGASEPELRVARTLRGLRQIARYNHMAVLSDLFAKHKVRDEEVARLAEIEDETQEKSQIVAAQELRTDLHDKVMKCHPKTISPEERQSYAAAIKTIEEHRFLVGRVYLGDHLRLHRLMMDVIGRLIDYAGAYERDTGTFLINASKQLGAGADWAVTIAGAANTDARTQTRKDLAHFNVLDRADGTPDLTALVNRAREMMAYDRKRKNAVPRSILDMLARLGLTLKWQMKDHLLQDATITQAAIKHLDKVRLTVGGPAAVTEARFSQDYLQMVAAVFNGSVQNPKPRRRDDGDAWHKPPKPATAQSQPDQKPPNKAPSAGSRLPPPQVGEVYEGVVVKVIDTGSLGFLAVEGVAGNIGLHISRLRRIREDAIIVGRRYRFRVEIYVPPKSNTSKLNAADLVRID
>NC_014034.1|WP_013067729.1|2162723_2164274_+|hypothetical-protein
MLSPQIASHPVAEHSLCVFYELDGIDPAGWTGPRFGNLTRNPGQGIPADQKAALQGRYAEDALWEADETLSAGDDFHAHLQELLSGARPDLVRFHRLTERGHRFLSTACLYEKTTPPADRIAKRLRLSLTSAAKERIAAAGVVPGELGLEVESLSLALFMTAQGLALCRFVVDREDGAPLSAVELLEATVALSRLNEVRWIDKKAKTPIEAPAFSMAALIGQMVFGSRSQAEVSRRLSSHAMVRFDAILPITDRDRYALMLARHYTTDYQLSPDIGRVEWVRDFETVRHAIALEGAATVIGPTEGAPTLTEFLRNFRTSTFDRHYLPIAILALHERAFLVARTAASIMSAAEMLDAQKSLRRLAELREAALVLRLCYRFSEQSHISMHNAVNLAWRKVLRLDEMLAELDDSIRDIADHLERIHRRAQERKFAGVAIMGGAIIAGFSTFSIVKDLYDLFKASQTYGWIGVCVGGIALIGVAAFAHRKSAVFGALDQDCSKNYTVHAMLEKMTRRSKD
>NC_014034.1|WP_013067730.1|2164486_2165695_-|site-specific-integrase
MGARDKLTAVKIRAAAPGRYGDGAGLYLDRTEDGGKWLYRYTIAGRRRDMGLGSLDAVTLAQARRERDRWAAVLASGRDPISERAREREAAATREDPSLSDLVDTVFGAIKHTLKGEGEAGRWMSPLRVHVLPKIGARPASSLRTADFVRVLQPIWRMKPTVAEKAYSRLNLCFKKGKRIGYAVDPDTLAAARELLGDLHIEPEHIAATRWQDAPVLFTRLAGDTSGLMCLRLLLLTAVRGDAARGARFNEIDGSLWIVPKERVKGRLKAATDFRVPLSSQALAIVAEARRLSNDPETGLLFPGDRGEPISPNALLKAVNKIGEAGRPHGFRTTFRTWVQDTLDGSHDLAAEAALGHVIGNKVRRAYARSDYLDQRAALMQRWADYVTGESVQVVQLRPSAG
>NC_014034.1|WP_013067731.1|2166078_2167413_+|trigger-factor
MQVTQTLNEGLKRGYTITLTGAELDAKVTEKLIEVQPEVEIKGFRKGKVPMAMLRKNFGDRVLGDVLNESVDGAIKDLLDQSGDRPALQPKVEMENGKDWKPGTDAIFTVSYEALPPIPAFDRATVTLERLVVKADEASVTEALENLAKSAQAFEDRKKGTKAKDGDQVVIDFEGFLGDEPFEGGKGEEYPLVLGSNSFIPGFEDQLVGAKAGEDVEVKVTFPAEYGAAHLAGKEATFKCHVHAVKAPKPAEIDDELAKKFGAADLEALKGQVASRLEAEYKGASRAILKRALLDILDAQVKFDLPPSLVEAEAGQIAHQLWHEENPDHHGHDHGAVEPTEEHKTLAERRVRLGLLLAELGRNEKIEVTDAEMTQAVLAAARQYPGHEREFFEFVKGNAQMQQQIRAPLYEEKVIDFIVAGAAVTEKEVSKEELQKAIEALDEL
>NC_014034.1|WP_013067732.1|2167948_2168521_-|50S-ribosomal-protein-L9
MQVILLERVAKLGQMGDVVKVRDGYARNFLLPQGKALRANDANIKSFEARKAQLEARNLETKKEAEAAAAKLEGQKFVVIRSASDAGALYGSVTPRDAAEAATAGGFSVDKRQVALKAPIKELGLHDVHVILHPEVQATITINVARSAEEAAIQAAGKSIQQLAAEADAAAEFEIAELFDEVGAAASDDE
>NC_014034.1|WP_013067733.1|2168533_2168761_-|30S-ribosomal-protein-S18
MATKPFFRRRKVCPFSGDNAPKIDYKDVRLLQRYISERGKIVPARITAVSAKKQRELAQAIKRARFLALLPYAVK
>NC_014034.1|WP_013067734.1|2168778_2169213_-|30S-ribosomal-protein-S6
MPLYEHVLIARQDLSNAQAEGLIEHFSTVIGDNGGKVLGTEYWGVKTMAYKINKNRKGHYGFLRTDAPSAAVQEMERLARLHDDVMRVLTIKVDGHDEGPSVQMQKRDDRGDREERGDRGDRGDRGPRGDRGPREDRGPRPERR
>NC_014034.1|WP_013067736.1|2169592_2170483_-|DMT-family-transporter
MGETKGGWKLWAVLALPPLFWAGNFIVARASRGEWPPVALSFGRWSIALIALLPFAWPWLRRDWPLYRRYFGRILLLTLPGVAAFNSLVYWGLQTSTATNGMLLNSTIPLLIMALGALFWGQRLGLWAILGLIVSTLGVAVVILQGSWERAAALDFARGDLIIFAAMVAWALYTMGLKTFPAEVNRIGLLAVQIALALPILAPFLVWEISSGRVPVWTPASIGALVYIGIVPSVLAYLFYTKAVEMAGPARAGQFIHLLPVYGAILSAAFLHEPLHLYHAAGFGLILGGIVLAGRR
>NC_014034.1|WP_013067737.1|2170556_2171942_-|hypothetical-protein
MEEPTPKDQTQTEAAASPAAPTETGADLAAKEVVEKEAAAKDAAAKEAKAREEAAAKDAAAKAEAARAAAKDAAAKPKPAAAAKPAAAAKPASDPKPAAEPVVEKVTRTSETEVAFALGGLAGNNAHGAGFLQAALEGGVHPRMISCTSGQIYWVWRYLQALAGGESLETHLAEQIETLQPFGQRDADLMHMALFGKSGVFRPSLFEWPFDVMQNLARSLDAVSRAGGNVFWLKEMMSLTPARTLVSLFPDSFFAEIAQAFNATGIGILFNAYDPREGVEYVHANPSALAQLGIAPGGRKSCAAARSTPKSRRRRCADGLWLYEYGFEGSPEGGFGALDGAYYRPVLLSELSCARTIHVVRPVNRKWLGPLPDSKLALEDMKTEVSFNGIYAAERDRMLMVNRWIAAGILRDPRFAPIEIYEIEVETQRSFFDYVFESMDVFENARGLGREAFSGGLAPAE
>NC_014034.1|WP_013067738.1|2172080_2173478_-|aldehyde-dehydrogenase-family-protein
MSPAAEAFARLRAGDARRRTEFTVQKRRAVLKRLASEIRAREAEIMAALAADLGKPAVEVRISEIIPILSEIRHTSRHLKAWAGVRRVRPTLSMIGTRATIRPEPKGTVLILAPWNYPLCLALGPLVSAIAAGNAAVVKPSELAPATSALVAKIVAACLPEDLVAVVEGGVETATALLAQPFDHIFFTGSPAVGKVVMAAAAKTLASVTLELGGKSPVILGPDADLKKAARMVAWGKFQNAGQTCIAPDHVFVPRAQEAGFTKALRAEIARMYGARPQASRSFARLIGAKHFERVRGMVTEAVGHGATLITGGEAEAASRYLAPTVLTHVPADAALMREEIFGPVLPVIAYDDLGAVLAGIEAGEKPLALYVFARDRKLIARICAATTSGAVGVNVTLAHFLHLNLPFGGIGQSGLGAAHGRWGFQAFSHEKPVLENRFAVLDPLMPPYGKLSARLARLVQALVG

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Crispr_ID: NC_014034_8

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_014034_8

2557467-2557791

Orphan

Consensus_repeat	Method
GCCCTCTCCTCCTCCCTGGGCGG	CRISPRCasFinder
GCCCTCTCCTCCTCCCTGGGCC	PILER-CR
GCCCTCTCCTCCTCCCTGGGCGG	CRISPRCasFinder

4 spacers

The CRISPR arrays of NC_014034_8

>merge|NC_014034|8|2557467-2557791|CRISPRCasFinder,PILER-CR,CRISPRCasFinder
ACCCTCTCCTCCTCCCTGGGTCTCGGAGATCGGCGGCATCCTCTCTCCTCCTCCCTGAGGATGCCGCCACCCCATACCGGCCCCATCTGCCGGACCAAGGATCAAGCCCCTCTCCTCCTCCCTGGGGCTTCGATAGAAGACGGCGGCCTCGTCCTCCTCCCAGAGGCCGCCCGTCTTCGACCTGATCCTGCCGCCCTCTCCTCCTCCCTGGGCGGCGGTGTGGTGCTGCCCACCTCCTCCCGGGCGGCACCGGAAAACCCGAGGCCCTCTCCTCCTCCCTGGGCCGAGGTTATCGCGGCGGCGCTCTCTCCTCCTCCCTGAGCGC

>NC_014034|8|7|2557467-2557596|CRISPRCasFinder
ACCCTCTCCTCCTCCCTGGGTCT	CGGAGATCGGCGGCAT
CCTCTCTCCTCCTCCCTGAGGAT	GCCGCCACCCCATACCGGCCCCATCTGCCGGACCAAGGATCAAG
CCCCTCTCCTCCTCCCTGGGGCTTCGATAGAAGACGGCGGCCTCGTCCTCCTCCCAGAGGCCGCCCGTCTTCGACCTGATCCTGCCGCCCTCTCCTCCTCCCTGGGCGG	CGGTGTGGTGCTGCCCACCTCCTCCCGGGCGGCACCGGAAAACCCGAG
GCCCTCTCCTCCTCCCTGGGCCG	AGGTTATCGCGGCGGC


>NC_014034|8|8|2557574-2557751|PILER-CR
CCCTCTCCTCCTCCCTGGGGCT	TCGATAGAAGACGGCGGCCTCGTCCTCCTCCCAGAGGCCGCCCGTCTTCGACCTGATCCTGCCG
CCCTCTCCTCCTCCCTGGGCGG	CGGTGTGGTGCTGCCCACCTCCTCCCGGGCGGCACCGGAAAACCCGAGG
CCCTCTCCTCCTCCCTGGGCC

>NC_014034|8|8|2557659-2557791|CRISPRCasFinder
	CGGAGATCGGCGGCAT
CCTCTCTCCTCCTCCCTGAGGAT	GCCGCCACCCCATACCGGCCCCATCTGCCGGACCAAGGATCAAG
CCCCTCTCCTCCTCCCTGGGGCTTCGATAGAAGACGGCGGCCTCGTCCTCCTCCCAGAGGCCGCCCGTCTTCGACCTGATCCTGCCGCCCTCTCCTCCTCCCTGGGCGG	CGGTGTGGTGCTGCCCACCTCCTCCCGGGCGGCACCGGAAAACCCGAG
GCCCTCTCCTCCTCCCTGGGCCG	AGGTTATCGCGGCGGC
GCTCTCTCCTCCTCCCTGAGCGC

Protein	Signature genes	Signature genes Name	Protein_function
NC_014034.1\|WP_013068098.1\|2559993_2561433_-\|signal-recognition-particle-docking-protein-FtsY	unknown	unknown	gnl\|CDD\|236686
NC_014034.1\|WP_013068093.1\|2555882_2556947_-\|Mrp/NBP35-family-ATP-binding-protein	unknown	unknown	gnl\|CDD\|378455
NC_014034.1\|WP_013068097.1\|2559109_2559724_-\|septation-protein-IspZ	unknown	unknown	gnl\|CDD\|367894
NC_014034.1\|WP_013068092.1\|2554642_2555137_-\|division/cell-wall-cluster-transcriptional-repressor-MraZ	unknown	unknown	gnl\|CDD\|234728
NC_014034.1\|WP_013068085.1\|2548571_2548991_+\|TonB-system-transport-protein-ExbD	unknown	unknown	gnl\|CDD\|183064
NC_014034.1\|WP_013068101.1\|2563716_2565180_-\|exodeoxyribonuclease-VII-large-subunit	unknown	unknown	gnl\|CDD\|234714
NC_014034.1\|WP_013068090.1\|2553229_2553628_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|227749
NC_014034.1\|WP_013068089.1\|2551433_2553233_-\|penicillin-binding-protein-2	unknown	unknown	gnl\|CDD\|223839
NC_014034.1\|WP_013068095.1\|2557936_2558734_+\|23S-rRNA-(adenine(2030)-N(6))-methyltransferase-RlmJ	unknown	unknown	gnl\|CDD\|225509
NC_014034.1\|WP_013068096.1\|2558740_2558989_-\|hypothetical-protein	unknown	unknown	unknown
NC_014034.1\|WP_013068088.1\|2550059_2551265_-\|GTP-binding-protein	unknown	unknown	gnl\|CDD\|223597
NC_014034.1\|WP_013068087.1\|2549789_2550041_-\|hypothetical-protein	unknown	unknown	unknown
NC_014034.1\|WP_013068102.1\|2565265_2566528_+\|phosphoribosylamine--glycine-ligase	unknown	unknown	gnl\|CDD\|234856
NC_014034.1\|WP_013068103.1\|2566721_2568101_-\|L-serine-ammonia-lyase	unknown	unknown	gnl\|CDD\|273233
NC_014034.1\|WP_013068091.1\|2553624_2554641_-\|16S-rRNA-(cytosine(1402)-N(4))-methyltransferase-RsmH	unknown	unknown	gnl\|CDD\|234597
NC_014034.1\|WP_013068086.1\|2548987_2549806_+\|TonB-family-protein	unknown	unknown	gnl\|CDD\|223880
NC_014034.1\|WP_013068104.1\|2568313_2569282_+\|Hint-domain-containing-protein	unknown	unknown	gnl\|CDD\|372590
NC_014034.1\|WP_013068094.1\|2557250_2557454_+\|DUF1127-domain-containing-protein	unknown	unknown	gnl\|CDD\|368980
NC_014034.1\|WP_080514689.1\|2561825_2563124_+\|alkane-1-monooxygenase	unknown	unknown	gnl\|CDD\|239589
NC_014034.1\|WP_013068100.1\|2563191_2563602_+\|hypothetical-protein	unknown	unknown	unknown

Protein	Function_ID	Function_description	E-value
NC_014034.1\|WP_013068098.1\|2559993_2561433_-\|signal-recognition-particle-docking-protein-FtsY	gnl\|CDD\|236686	PRK10416, PRK10416, signal recognition particle-docking protein FtsY; Provisional.	1.78273e-167
NC_014034.1\|WP_013068093.1\|2555882_2556947_-\|Mrp/NBP35-family-ATP-binding-protein	gnl\|CDD\|378455	pfam10609, ParA, NUBPL iron-transfer P-loop NTPase. This family contains ATPases involved in plasmid partitioning. It also contains the cytosolic Fe-S cluster assembling factor NBP35 which is required for biogenesis and export of both ribosomal subunits.	1.42492e-134
NC_014034.1\|WP_013068097.1\|2559109_2559724_-\|septation-protein-IspZ	gnl\|CDD\|367894	pfam04279, IspA, Intracellular septation protein A.	3.82381e-61
NC_014034.1\|WP_013068092.1\|2554642_2555137_-\|division/cell-wall-cluster-transcriptional-repressor-MraZ	gnl\|CDD\|234728	PRK00326, PRK00326, transcriptional regulator MraZ.	4.15686e-41
NC_014034.1\|WP_013068085.1\|2548571_2548991_+\|TonB-system-transport-protein-ExbD	gnl\|CDD\|183064	PRK11267, PRK11267, biopolymer transport protein ExbD; Provisional.	2.11206e-53
NC_014034.1\|WP_013068101.1\|2563716_2565180_-\|exodeoxyribonuclease-VII-large-subunit	gnl\|CDD\|234714	PRK00286, xseA, exodeoxyribonuclease VII large subunit; Reviewed.	0
NC_014034.1\|WP_013068090.1\|2553229_2553628_-\|hypothetical-protein	gnl\|CDD\|227749	COG5462, COG5462, Predicted secreted (periplasmic) protein [Function unknown].	7.90696e-08
NC_014034.1\|WP_013068089.1\|2551433_2553233_-\|penicillin-binding-protein-2	gnl\|CDD\|223839	COG0768, FtsI, Cell division protein FtsI/penicillin-binding protein 2 [Cell envelope biogenesis, outer membrane].	9.63486e-127
NC_014034.1\|WP_013068095.1\|2557936_2558734_+\|23S-rRNA-(adenine(2030)-N(6))-methyltransferase-RlmJ	gnl\|CDD\|225509	COG2961, ComJ, Protein involved in catabolism of external DNA [General function prediction only].	9.22188e-74
NC_014034.1\|WP_013068088.1\|2550059_2551265_-\|GTP-binding-protein	gnl\|CDD\|223597	COG0523, COG0523, Putative GTPases (G3E family) [General function prediction only].	3.51233e-113
NC_014034.1\|WP_013068104.1\|2568313_2569282_+\|Hint-domain-containing-protein	gnl\|CDD\|372590	pfam13403, Hint_2, Hint domain. This domain is found in inteins.	6.51974e-41
NC_014034.1\|WP_013068103.1\|2566721_2568101_-\|L-serine-ammonia-lyase	gnl\|CDD\|273233	TIGR00720, hypothetical_protein_NEICINOT_00681, L-serine dehydratase, iron-sulfur-dependent, single chain form. This enzyme is also called serine deaminase and L-serine dehydratase 1. L-serine ammonia-lyase converts serine into pyruvate in the gluconeogenesis pathway from serine. This enzyme is comprised of a single chain in Escherichia coli, Mycobacterium tuberculosis, and several other species, but has separate alpha and beta chains in Bacillus subtilis and related species. The beta and alpha chains are homologous to the N-terminal and C-terminal regions, respectively, but are rather deeply branched in a UPGMA tree. This enzyme requires iron and dithiothreitol for activation in vitro, and is a predicted 4Fe-4S protein. Escherichia coli Pseudomonas aeruginosa have two copies of this protein. [Energy metabolism, Amino acids and amines, Energy metabolism, Glycolysis/gluconeogenesis].	0
NC_014034.1\|WP_013068091.1\|2553624_2554641_-\|16S-rRNA-(cytosine(1402)-N(4))-methyltransferase-RsmH	gnl\|CDD\|234597	PRK00050, PRK00050, 16S rRNA (cytosine(1402)-N(4))-methyltransferase RsmH.	5.49887e-148
NC_014034.1\|WP_013068086.1\|2548987_2549806_+\|TonB-family-protein	gnl\|CDD\|223880	COG0810, TonB, Periplasmic protein TonB, links inner and outer membranes [Cell envelope biogenesis, outer membrane].	2.24867e-16
NC_014034.1\|WP_013068094.1\|2557250_2557454_+\|DUF1127-domain-containing-protein	gnl\|CDD\|368980	pfam06568, DUF1127, Domain of unknown function (DUF1127). This family is found in several hypothetical bacterial proteins. In some cases it represents it represents the C-terminal region whereas in others it represents the whole sequence.	9.08076e-06
NC_014034.1\|WP_080514689.1\|2561825_2563124_+\|alkane-1-monooxygenase	gnl\|CDD\|239589	cd03512, Alkane-hydroxylase, Alkane hydroxylase is a bacterial, integral-membrane di-iron enzyme that shares a requirement for iron and oxygen for activity similar to that of the non-heme integral-membrane acyl coenzyme A (CoA) desaturases and acyl lipid desaturases. The alk genes in Pseudomonas oleovorans encode conversion of alkanes to acyl CoA. The alkane omega-hydroxylase (AlkB) system is responsible for the initial oxidation of inactivated alkanes. It is a three-component system comprising a soluble NADH-rubredoxin reductase (AlkT), a soluble rubredoxin (AlkG), and the integral membrane oxygenase (AlkB). AlkB utilizes the oxygen rebound mechanism to hydroxylate alkanes. This mechanism involves homolytic cleavage of the C-H bond by an electrophilic metal-oxo intermediate to generate a substrate-based radical. As with other members of this superfamily, this domain family has extensive hydrophobic regions that would be capable of spanning the membrane bilayer at least twice. The active site structure of AlkB is not known, however, spectroscopic and genetic evidence points to a nitrogen-rich coordination environment located in the cytoplasm with as many as eight histidines coordinating the two iron ions and a carboxylate residue bridging the two metals. Like all other members of this superfamily, there are eight conserved histidines seen in the histidine cluster motifs: HXXXH, HXXXHH, and HXXHH. These histidine residues are reported to be catalytically essential and proposed to be the ligands for the iron atoms contained within the homolog, stearoyl CoA desaturase. Also included in this CD are terminal alkane hydroxylases (AlkM), xylene monooxygenase hydroxylases (XylM), p-cymene monooxygenase hydroxylases (CymAa), and other related proteins.	6.77736e-97
NC_014034.1\|WP_013068102.1\|2565265_2566528_+\|phosphoribosylamine--glycine-ligase	gnl\|CDD\|234856	PRK00885, PRK00885, phosphoribosylamine--glycine ligase; Provisional.	0

>NC_014034.1|WP_013068094.1|2557250_2557454_+|DUF1127-domain-containing-protein
MALVSDIRTTDSGFSNFLASIREALARRKVYRQTLAELRSLSNRELNDLGMHRSMLTRIALEAAYGK
>NC_014034.1|WP_013068093.1|2555882_2556947_-|Mrp/NBP35-family-ATP-binding-protein
MTLTKESVLEALRKTALPGGGDAVGRNLVHALAVESGVVRFVLEGAPEAELLVIRPVLEAAVRALPGVQSLSVVIPAGPSKAPGGGVKIGGHAKPQDGPLPVPGVAHVIAVGSGKGGVGKSTVASNLAVALARAGKRVGLLDADLYGPSQPRMMGATEKPASPDGQTILPVRAHGVVLMSLGLMLREDEAVIWRGPMLMGALQQMLGQVKWDHFGPLDVLVIDLPPGTGDIQLSLCQKTVLDGAVIVSTPQDIALLDAKKALDMFAKLKLPVLGLIENMSTYVCPNCGHEAHLFGHGGVEAEAARLGLPFLGSLPLALEVREAGDAGRPVALGTGAAAGAYAAIAAELIGRGVA
>NC_014034.1|WP_013068092.1|2554642_2555137_-|division/cell-wall-cluster-transcriptional-repressor-MraZ
MAGMFIGEYTFKVDSKGRVSIPALFRRELEEGDPEAAVTKRPRLVIVYGADTQKMLQVHSFAGFQKLAAAINARPYSDPSRAILQRFVLNKAHPTEIDPDGRLVLPAQLRERFQLTGDAYFAGMGETFEIWNPETFAAVDQARLEKLMAEMGEDFDPLSLLNGG
>NC_014034.1|WP_013068091.1|2553624_2554641_-|16S-rRNA-(cytosine(1402)-N(4))-methyltransferase-RsmH
MDRPDTPHIPVLLRPLLQAVAPVLGTWLDGTFGAGGYARGLLAAGAGRVIGIDRDPLAFEMAAPWRGEFGERLVLVENTFSNLDAVAAEIAPEGLNGVVLDLGVSSMQLDQAERGFSFLRDGPLDMRMSQSGPSAADLVNTAEEGALADILYHYGEERASRRIARAIVEARKSAPYESTKQLVATIERCLPRPKPGQSHPATRSFQALRIAVNDEFGQLIAGLEAAERALKPGGKLAVVTFHSLEDRVVKRFFQARAGRAPGGSRYAPEAAPEAAAFDLVTRKGVGPDEIELAQNPRARSAILRIGARTDSPAGRADRSSLGLPAPLFETDRSRGRPR
>NC_014034.1|WP_013068090.1|2553229_2553628_-|hypothetical-protein
MKTISYILVSLCVLGLAFWAYHVNYATQDREQELRALNAEIADLQEGLSVLRAEWAYLNRPERLRELVNLNFASLGLLPMTPDQFGTAAMVAYPAPEGTDPLSIDQAVAQAIEVSAPPTDDESSRIAEEEAQ
>NC_014034.1|WP_013068089.1|2551433_2553233_-|penicillin-binding-protein-2
MSPRTPLRPLARILDARARGENPDLIERANIRARGEAGREAARARVAWRIGLVIGIFCVCFGAVGVRMGTLAASTPEEPQRADTAPAILAQRADITDREGRVLATNLVTHALYAQPPMMVDPVGTAKKLAKIFPDLDAKRLAADFTGTRKFVWIKKKISPEQLQQVHDIGEPGLLFGPREMRLYPNGRLAAHVLGGARFGNEGVDSAEIIGTAGVEKAFDGWLRDPANNGAPLKLSIDLTVQQAVEEILAGGMKLMNAKGATAVVMDAHSGEIVALASLPDFDPNDRPTPLVKGDASDSPLFNRAVQGVYELGSTFKIFAVAQALELGLVNPTTMLDTKSPMVWGRFRIRDFHNYGPALSITDIVVESSNVGTARIALLIGGQRQKAFLESLGFMAPTPVELSEAPSGRPIVPGKWSEITSMTVGYGHGLAASPLHLAAAYATIANGGYRVKPTLVHAATHERGPQVMSTEAARKSLAMMRAVVTRGTASFADVKGYEVAGKTGTADKVKPGGGYYDNKVIATFASAFPASDPKYVLVLTLDEPSSFAANETRRTAGWTAVPVAAEVIRRIAPILGLRPADSVPEVLDGIQLVKAAKGH
>NC_014034.1|WP_013068088.1|2550059_2551265_-|GTP-binding-protein
MTLSPTDPRLPVSVLSGFLGAGKTTLLNHVLNNRAGRRVAVIVNDMSEVNIDADLIREGTELNRAEEALVEMTNGCICCTLRDDLLKGVRALAEAGRFDYLLIEGTGVAEPLPVATTFDFRDETGASLSDIARLDCMVTVVDAINLTKDFASSDFLADRGETAGAEDDRTLVNLLTEQIEFADVVVLNKVTDAGPERLQIARQIVKALNPDARLIETDFGQVPAEAIFDTGLFDFARAAEHPLWAKELYGFANHTPETEEYGISSFVYHARAPFDPARIEAALGGALPGVIRAKGHFWLATRPDWAVEFSLAGASARVTPLGRWWASVPPERLPAHPDAQREIARNWAEPWGDRRQEIVFIGVDLDRDAICARLNAALVPAADFTPEAWADLPDPFPRWGA
>NC_014034.1|WP_013068087.1|2549789_2550041_-|hypothetical-protein
MRRNLTTSLRHRVRADPMAAFDRLPAPARAWARQAVLPWSAASVARIWARALAETGCPEAALARLHLAEARTLAREPSLSAKT
>NC_014034.1|WP_013068086.1|2548987_2549806_+|TonB-family-protein
MSLALTDPPEVPGRALLWGLALSLALHAVAVSVLSQTEAAPAALVAAGAGGEDLDGLEAIAATFVDLAPQIQLPEPEMALPLTAPVIDIPQVRLPDPVLLPPEPPKITPPKRAEEKPKPPPPKPKPEPRPRAEKPKQAKPAPVQSESRAASRAAGSGAGAQAGTGGTDAQATVSAGTTKSLLAKWGATIRTRIERRKSYPAAAGRAAGSVGLALKVSRDGALLSAAVNRSSGHPALDAAALAAVQKAGKFPAAPAELAKPSYAFSVAVKFSR
>NC_014034.1|WP_013068085.1|2548571_2548991_+|TonB-system-transport-protein-ExbD
MAVRLSDGEDLTPEAAINITPFIDVMLVLLIIFMVAAPLSTVDVPLDLPVASGQPQPRPPEPVVLSLSAEKGLMLGRDPVSATDLPARLAEATQGDLATRIFVSADKSVPYGEMMGLLNQLRAGGYLKIGLVGLEEAAP
>NC_014034.1|WP_013068095.1|2557936_2558734_+|23S-rRNA-(adenine(2030)-N(6))-methyltransferase-RlmJ
MLSYQHAYHAGNLADVHKHALMAALLDYMTRKDKPLSYMETHAGRGLYALDGAEAAKTGEAAAGIARAEAGRWFAPDHPYSRALAAVRKAHGPAAYPGSPLLAATLLRPVDSLQLCELHPQEFAALKAAMAAHGGIFHQKDGLQMALAMCPPTPRRGVLLIDPSWEVKSDYETVPKLVGQLARKWNVGVIALWYPILAPHVAVAPAQRAMVRALMADHPEALLSEVQFPPAREGHGMVGSGMVLLNPPWGLDEEAAQIGRRFAKL
>NC_014034.1|WP_013068096.1|2558740_2558989_-|hypothetical-protein
MSTVTANASETPAEVGFHHEPLALLLVVLFGPVGLLYTSVRGGVALILVALVGAIFTMGFAPLAVWPVCILWVLAAGMMRRS
>NC_014034.1|WP_013068097.1|2559109_2559724_-|septation-protein-IspZ
MAERKPIPQGLKLALDFGPLVVFFAAFFLLRDHPVTLGGETYGGFVLATAVFVPVLIASMAVLWRLSGHLAPMQVATLVLVTVFGGLSVWFNDPRFFKMKPTLIYLLFAALLGFGLIRGKPWLQLVMDGAIPMRAEGWVILTRRLVAFFLFLAIANEVIWRNFSDATWVNFKTFGLTILLMGFFVAQSRLFARFAPEEGGKSES
>NC_014034.1|WP_013068098.1|2559993_2561433_-|signal-recognition-particle-docking-protein-FtsY
MSFFNKLKSRLTRSSSKIEEGLDAIIAEAPDTTPEPEAEALAAPVAAPEPEPVVEPEPAVEQEPEPAVEPEPEPAVEPEPEPVVEPEPEPAVEPEPEPVAEPEPEPVAEPEPVAEPEPEPVVEPEPEPAAEPDPEPVAEPEPAKRGFFGRLLGRGGNGSEPETAPEPEPEPEPAPQPEPVAAVAPGRAGLLGRLVSRPDVPRRVLDDAMLESIEDLLIAADMGVDTALRVTANLAEGRMGRKLSVPELKDILAAEVARIMEPVARPMPLYARRPQVVLVVGVNGSGKTTTIGKLASQFRAAGKSVIIAAGDTFRAAAVEQLKVWGDRAGVPVMTAPEGADPASFAYDALTRAAAEGVDLLMIDTAGRLQNRADLMEELAKIVRVIRKIDESAPHNTLLVLDATTGQNALAQVEVFRKISDVSGLVMTKLDGTAKGGVLVALADKFGLPIHAIGVGEQIDDLSPFDPEEFAAALVGIEAD
>NC_014034.1|WP_080514689.1|2561825_2563124_+|alkane-1-monooxygenase
MVALRSLRKIGRETPDVDTFALFAFAPVPLIFLGALFGGIFSWLAIAWITVGIFVLDRRAPKPAPDAPEGAAFPKADKLSSALAITHFVLLPIVVASLAGFAGISTMGTLGLMIAAALWFGQVSNANAHELIHRADRKLFNLGKWVYISLLYGHHVSAHRLVHHVSVATPADPATATLGESYWNYASRTWSESFKAGYAKEKAIIEARIKANPGKPTIRERINRINPYATYVLGGLWFVIGAGLLFGSAGFASFLFLCALTQAQLMLSDYVQHYGLVRKETAPGDYEPVSAAHSWDAIETGSALMMLNAPRHSDHHAHPARPYPALQLGDLKEPGRPILPYSLPVMAMLALVPSQFAKLMDHRVLAVRKGESVYSEPKPKQAPAPAAAPTDAPTDDAGPLVLTDAEPAEAPAPEVSQAPAAPAAAEREKADA
>NC_014034.1|WP_013068100.1|2563191_2563602_+|hypothetical-protein
MRPVFISLALALTPLAALAEDIGPPLTAEQFDALTLGKTITYSAGNTTYGIEEYRPGRKVVWAFAAGDCEEGDWFPQGEQICFDYHSPDVGLQCWTFHLQGDALVAWFEGKRDGAPLVSLDTSAAPLNCPGPEVGV
>NC_014034.1|WP_013068101.1|2563716_2565180_-|exodeoxyribonuclease-VII-large-subunit
MDILDDGPEASKTGPSGNTPEFTVSEISGAVKRVIEGEFTRVRVRGEVGRVSRPGSGHLYFDLKDPNAVIAAVSWKGQVARMQIRPEEGMEVIATGKLTTFPGQSKYQLIVDDVEPAGAGALMAMLEARRKALAAEGLFDPARKKPIPYLPAVIGVVTSPSGAVIRDILHRLRDRFPRRVLIWPVAVQGQACAAEVAAAIRGFNALAPGGKVPRPDLIIVARGGGSLEDLWGFNEEAVVRAAAESKIPLISAVGHETDTTLIDFAADRRAPTPTAAAEMAVPVRAELATRLSEMQARISRATQTRMASRAQRLADLSRALGRPEAITRPRRQRFDLVADRLLPALRMVVVRKRAAFAPLEARISPKLLQTYLRVERDRLAGLSDRLLRAEQARLTRAQDRFARLAAMLQTLGYQETLRRGYAVVRGPADQVLTSAATAAGLAPLEIEFQDGRLRVLPSDAPPPAPAPKPAAKPRKAAKTPPDQGSLF
>NC_014034.1|WP_013068102.1|2565265_2566528_+|phosphoribosylamine--glycine-ligase
MNILILGSGGREHALAWAVKQNPKCDRLIVAPGNAGIGQLAELAAIDPCDATAVLACVAENAVDFVIVGPEAPLAAGVADALRAAGVLTFGPSAQAAQLEASKAFTKEICDACGAPTAAWARFADLEAALAHVRAQGAPIVVKADGLAAGKGVIVAMTLAEAEAGLREIFGGAFGAAGAEVVIEEFMAGEEASFFILSDGVNVAPIGTAQDHKRVGDGDTGPNTGGMGAYSPAPVLSAAIQEQVLAEIIRPTVAQMARRGMPFQGVLYAGLMIENGRARLVEYNVRFGDPECQVLMMRLGGQALDLLQACAEGRLDQITAQWAEDCALTVVMAARGYPGTYEKGSEIKGLDSLPETSAQMVFHAGTTAQDGRILATGGRVLNVTARAATLAEAQQRAYAMVDAIDWPEGFCRRDIGWRAL
>NC_014034.1|WP_013068103.1|2566721_2568101_-|L-serine-ammonia-lyase
MFLSVFDIFKVGVGPSSSHTMGPMVAGGRFLDMLRASPFHPRHLRVRLYGSLAFTGKGHATDRATILGLAGFLPESYEAEKAEAVLAANRESLTLTPPGLGPLHFDPDHDLIFDYGHPLPGHANGMVIEARDAEGDVILRETFYSIGGGFVLTEAEHAAIDDKTLAAPSPVPYPFRKADEMLAMAQASGLTIAQMKRRNERRFRSEPEIEAGLARIWQVMNDCLTRGLETDGVLPGGLKVKRRAKAIHAALEAERGLNMVAPHTINDWISCYAMAVNEENAAGGQVVTAPTNGAAGVVPAVIRYWLDHVPGASGSQVGDFLLTAAAVGGIIKTNASISGAECGCQAEVGSAAAMAAAGLAAVLGGTPEQIENAAEIALEHHLGMTCDPVKGLVQVPCIERNGLGAIKAISAASLALRGDGTHFVPLDAAIETMRQTGRDMHEHYKETSLGGLAVNVPNC
>NC_014034.1|WP_013068104.1|2568313_2569282_+|Hint-domain-containing-protein
MPTLCFWPLTEVTSSGPDPFGSVPGSEEAALGRAHFVLRPGAAMRFIDLPEADGADPDGAAIEPDVSYRIRPLASEDLADTQVVHLIDTPATGRGLAASERLKPGRAYRITGLETEGMLTPFASQAICFAAGTLIATRRGPKPVEDLGPEDRLQTSDNGYRPVQWVGRWRVGGLGATAPVRFAPGVLGNDRALFLSGQHRVLIRPATGPLAGEEVLVAAKALVGLPGIARAPRARVDWVHVMMPTHEVIFAENARAETMLAGPKTMSVLEPTQALALRQSLSSDPFTGLPARPIVPTPKVAKLILQHRRGHSPLESAGLVRR

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity
NC_014034_6	6.5\|1434579\|35\|NC_014034\|CRT,PILER-CR,CRISPRCasFinder	1434579-1434613	35	NC_014034.1	1063774-1063808	2	0.943
NC_014034_6	6.8\|1434778\|35\|NC_014034\|CRT,PILER-CR,CRISPRCasFinder	1434778-1434812	35	NC_014034.1	1063774-1063808	2	0.943

1. spacer 6.5|1434579|35|NC_014034|CRT,PILER-CR,CRISPRCasFinder matches to position: 1063774-1063808, mismatch: 2, identity: 0.943

gacgcgctgaaggagggtgatctcggtggcgcctt	CRISPR spacer
gacgcgctgaaggaaggtgatcttggtggcgcctt	Protospacer
**************.********.***********

2. spacer 6.8|1434778|35|NC_014034|CRT,PILER-CR,CRISPRCasFinder matches to position: 1063774-1063808, mismatch: 2, identity: 0.943

gacgcgctgaaggagggtgatctcggtggcgcctt	CRISPR spacer
gacgcgctgaaggaaggtgatcttggtggcgcctt	Protospacer
**************.********.***********

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NC_014034_5	5.6\|1395731\|33\|NC_014034\|PILER-CR,CRISPRCasFinder,CRT	1395731-1395763	33	NC_020489	Rhodobacter phage RcapNL, complete genome	39291-39323	0	1.0
NC_014034_5	5.6\|1395731\|33\|NC_014034\|PILER-CR,CRISPRCasFinder,CRT	1395731-1395763	33	JF974309	Rhodobacter phage RcNL1, * SEQUENCING IN PROGRESS *, 5 unordered pieces	49442-49474	0	1.0
NC_014034_5	5.35\|1397665\|35\|NC_014034\|PILER-CR,CRISPRCasFinder,CRT	1397665-1397699	35	NC_020489	Rhodobacter phage RcapNL, complete genome	22575-22609	0	1.0
NC_014034_5	5.35\|1397665\|35\|NC_014034\|PILER-CR,CRISPRCasFinder,CRT	1397665-1397699	35	JF974309	Rhodobacter phage RcNL1, * SEQUENCING IN PROGRESS *, 5 unordered pieces	22549-22583	0	1.0
NC_014034_5	5.38\|1397868\|35\|NC_014034\|PILER-CR,CRISPRCasFinder,CRT	1397868-1397902	35	NC_020489	Rhodobacter phage RcapNL, complete genome	29394-29428	0	1.0
NC_014034_5	5.38\|1397868\|35\|NC_014034\|PILER-CR,CRISPRCasFinder,CRT	1397868-1397902	35	JF974309	Rhodobacter phage RcNL1, * SEQUENCING IN PROGRESS *, 5 unordered pieces	29368-29402	0	1.0
NC_014034_5	5.9\|1395931\|34\|NC_014034\|PILER-CR,CRISPRCasFinder,CRT	1395931-1395964	34	NC_020489	Rhodobacter phage RcapNL, complete genome	18758-18791	1	0.971
NC_014034_5	5.9\|1395931\|34\|NC_014034\|PILER-CR,CRISPRCasFinder,CRT	1395931-1395964	34	JF974309	Rhodobacter phage RcNL1, * SEQUENCING IN PROGRESS *, 5 unordered pieces	18732-18765	1	0.971
NC_014034_5	5.16\|1396402\|36\|NC_014034\|PILER-CR,CRISPRCasFinder,CRT	1396402-1396437	36	NC_020489	Rhodobacter phage RcapNL, complete genome	20789-20824	1	0.972
NC_014034_5	5.16\|1396402\|36\|NC_014034\|PILER-CR,CRISPRCasFinder,CRT	1396402-1396437	36	JF974309	Rhodobacter phage RcNL1, * SEQUENCING IN PROGRESS *, 5 unordered pieces	20763-20798	1	0.972
NC_014034_5	5.11\|1396064\|35\|NC_014034\|PILER-CR,CRISPRCasFinder,CRT	1396064-1396098	35	NC_020489	Rhodobacter phage RcapNL, complete genome	7697-7731	2	0.943
NC_014034_5	5.11\|1396064\|35\|NC_014034\|PILER-CR,CRISPRCasFinder,CRT	1396064-1396098	35	JF974309	Rhodobacter phage RcNL1, * SEQUENCING IN PROGRESS *, 5 unordered pieces	7671-7705	2	0.943
NC_014034_6	6.2\|1434382\|33\|NC_014034\|CRT,PILER-CR,CRISPRCasFinder	1434382-1434414	33	NC_020489	Rhodobacter phage RcapNL, complete genome	9191-9223	2	0.939
NC_014034_6	6.2\|1434382\|33\|NC_014034\|CRT,PILER-CR,CRISPRCasFinder	1434382-1434414	33	JF974309	Rhodobacter phage RcNL1, * SEQUENCING IN PROGRESS *, 5 unordered pieces	9165-9197	2	0.939
NC_014034_6	6.5\|1434579\|35\|NC_014034\|CRT,PILER-CR,CRISPRCasFinder	1434579-1434613	35	NC_016165	Rhodobacter phage RcapMu, complete genome	30436-30470	2	0.943
NC_014034_6	6.5\|1434579\|35\|NC_014034\|CRT,PILER-CR,CRISPRCasFinder	1434579-1434613	35	JF974309	Rhodobacter phage RcNL1, * SEQUENCING IN PROGRESS *, 5 unordered pieces	38921-38955	2	0.943
NC_014034_6	6.8\|1434778\|35\|NC_014034\|CRT,PILER-CR,CRISPRCasFinder	1434778-1434812	35	NC_016165	Rhodobacter phage RcapMu, complete genome	30436-30470	2	0.943
NC_014034_6	6.8\|1434778\|35\|NC_014034\|CRT,PILER-CR,CRISPRCasFinder	1434778-1434812	35	JF974309	Rhodobacter phage RcNL1, * SEQUENCING IN PROGRESS *, 5 unordered pieces	38921-38955	2	0.943
NC_014034_2	2.2\|1349659\|35\|NC_014034\|PILER-CR	1349659-1349693	35	NZ_CP049788	Ralstonia solanacearum strain B2 plasmid unnamed, complete sequence	1368207-1368241	6	0.829
NC_014034_2	2.2\|1349659\|35\|NC_014034\|PILER-CR	1349659-1349693	35	CP023013	Ralstonia solanacearum strain T110 plasmid unnamed, complete sequence	548712-548746	6	0.829
NC_014034_2	2.2\|1349659\|35\|NC_014034\|PILER-CR	1349659-1349693	35	NZ_CP022783	Ralstonia solanacearum strain SL3755 plasmid unnamed, complete sequence	550205-550239	6	0.829
NC_014034_2	2.2\|1349659\|35\|NC_014034\|PILER-CR	1349659-1349693	35	NZ_CP022795	Ralstonia solanacearum strain SL2330 plasmid unnamed, complete sequence	549300-549334	6	0.829
NC_014034_5	5.24\|1396935\|34\|NC_014034\|PILER-CR,CRISPRCasFinder,CRT	1396935-1396968	34	NZ_CP032348	Azospirillum brasilense strain MTCC4039 plasmid p4, complete sequence	221889-221922	6	0.824
NC_014034_5	5.24\|1396935\|34\|NC_014034\|PILER-CR,CRISPRCasFinder,CRT	1396935-1396968	34	NZ_CP015740	Shinella sp. HZN7 plasmid pShin-04, complete sequence	97217-97250	6	0.824
NC_014034_5	5.28\|1397199\|35\|NC_014034\|PILER-CR,CRISPRCasFinder,CRT	1397199-1397233	35	NZ_CP012399	Chelatococcus sp. CO-6 plasmid pCO-6, complete sequence	757051-757085	6	0.829
NC_014034_5	5.33\|1397532\|35\|NC_014034\|PILER-CR,CRISPRCasFinder,CRT	1397532-1397566	35	NZ_CP016083	Streptomyces sp. SAT1 plasmid unnamed3, complete sequence	469047-469081	6	0.829
NC_014034_7	7.6\|2157833\|33\|NC_014034\|CRT,PILER-CR	2157833-2157865	33	NZ_CP013555	Rhizobium phaseoli strain N931 plasmid pRphaN931c, complete sequence	80925-80957	6	0.818
NC_014034_7	7.6\|2157833\|33\|NC_014034\|CRT,PILER-CR	2157833-2157865	33	NZ_CP013578	Rhizobium phaseoli strain N671 plasmid pRphaN671d, complete sequence	79004-79036	6	0.818
NC_014034_7	7.6\|2157833\|33\|NC_014034\|CRT,PILER-CR	2157833-2157865	33	NZ_CP013566	Rhizobium phaseoli strain N831 plasmid pRphaN831c, complete sequence	80925-80957	6	0.818
NC_014034_7	7.6\|2157833\|33\|NC_014034\|CRT,PILER-CR	2157833-2157865	33	NZ_CP013572	Rhizobium phaseoli strain N771 plasmid pRphaN671d, complete sequence	79004-79036	6	0.818
NC_014034_2	2.2\|1349659\|35\|NC_014034\|PILER-CR	1349659-1349693	35	NZ_AP022593	Mycolicibacterium arabiense strain JCM 18538 plasmid pJCM18538, complete sequence	5263725-5263759	7	0.8
NC_014034_5	5.24\|1396935\|34\|NC_014034\|PILER-CR,CRISPRCasFinder,CRT	1396935-1396968	34	CP054924	Verrucosispora sp. NA02020 plasmid unnamed, complete sequence	64148-64181	7	0.794
NC_014034_5	5.24\|1396935\|34\|NC_014034\|PILER-CR,CRISPRCasFinder,CRT	1396935-1396968	34	NZ_CP017947	Bosea sp. Tri-49 plasmid unnamed1, complete sequence	114898-114931	7	0.794
NC_014034_5	5.24\|1396935\|34\|NC_014034\|PILER-CR,CRISPRCasFinder,CRT	1396935-1396968	34	NZ_CP039340	Ralstonia solanacearum strain UW386 plasmid pUW386, complete sequence	1142455-1142488	7	0.794
NC_014034_5	5.33\|1397532\|35\|NC_014034\|PILER-CR,CRISPRCasFinder,CRT	1397532-1397566	35	NZ_AP014705	Methylobacterium aquaticum strain MA-22A plasmid pMaq22A_1p, complete sequence	138046-138080	7	0.8
NC_014034_7	7.2\|2157830\|36\|NC_014034\|CRISPRCasFinder	2157830-2157865	36	NZ_CP013555	Rhizobium phaseoli strain N931 plasmid pRphaN931c, complete sequence	80925-80960	7	0.806
NC_014034_7	7.2\|2157830\|36\|NC_014034\|CRISPRCasFinder	2157830-2157865	36	NZ_CP013578	Rhizobium phaseoli strain N671 plasmid pRphaN671d, complete sequence	79004-79039	7	0.806
NC_014034_7	7.2\|2157830\|36\|NC_014034\|CRISPRCasFinder	2157830-2157865	36	NZ_CP013566	Rhizobium phaseoli strain N831 plasmid pRphaN831c, complete sequence	80925-80960	7	0.806
NC_014034_7	7.2\|2157830\|36\|NC_014034\|CRISPRCasFinder	2157830-2157865	36	NZ_CP013572	Rhizobium phaseoli strain N771 plasmid pRphaN671d, complete sequence	79004-79039	7	0.806
NC_014034_7	7.6\|2157833\|33\|NC_014034\|CRT,PILER-CR	2157833-2157865	33	NZ_CP006991	Rhizobium sp. IE4771 plasmid pRetIE4771e, complete sequence	238917-238949	7	0.788
NC_014034_7	7.7\|2157903\|31\|NC_014034\|CRT	2157903-2157933	31	NZ_CP021084	Deinococcus ficus strain CC-FR2-10 plasmid pDFI3, complete sequence	165165-165195	7	0.774
NC_014034_2	2.2\|1349659\|35\|NC_014034\|PILER-CR	1349659-1349693	35	NZ_CP041652	Streptomyces sp. RLB1-9 plasmid pRLB1-9.2, complete sequence	46702-46736	8	0.771
NC_014034_3	3.1\|1356338\|31\|NC_014034\|PILER-CR	1356338-1356368	31	NZ_CP039965	Pseudorhodobacter sp. S12M18 plasmid unnamed1, complete sequence	325033-325063	8	0.742
NC_014034_5	5.24\|1396935\|34\|NC_014034\|PILER-CR,CRISPRCasFinder,CRT	1396935-1396968	34	NC_009620	Sinorhizobium medicae WSM419 plasmid pSMED01, complete sequence	1109735-1109768	8	0.765
NC_014034_5	5.24\|1396935\|34\|NC_014034\|PILER-CR,CRISPRCasFinder,CRT	1396935-1396968	34	NZ_CP012940	Ralstonia solanacearum strain UW163 plasmid unnamed, complete sequence	614519-614552	8	0.765
NC_014034_5	5.24\|1396935\|34\|NC_014034\|PILER-CR,CRISPRCasFinder,CRT	1396935-1396968	34	NZ_CP012944	Ralstonia solanacearum strain IBSBF1503 plasmid unnamed, complete sequence	1279919-1279952	8	0.765
NC_014034_5	5.24\|1396935\|34\|NC_014034\|PILER-CR,CRISPRCasFinder,CRT	1396935-1396968	34	NC_017575	Ralstonia solanacearum Po82 megaplasmid, complete sequence	1117903-1117936	8	0.765
NC_014034_5	5.24\|1396935\|34\|NC_014034\|PILER-CR,CRISPRCasFinder,CRT	1396935-1396968	34	NZ_CP026308	Ralstonia solanacearum strain IBSBF 2571 plasmid unnamed, complete sequence	1117849-1117882	8	0.765
NC_014034_5	5.24\|1396935\|34\|NC_014034\|PILER-CR,CRISPRCasFinder,CRT	1396935-1396968	34	NZ_CP051295	Ralstonia solanacearum strain CIAT_078 plasmid megaplasmid, complete sequence	606491-606524	8	0.765
NC_014034_5	5.24\|1396935\|34\|NC_014034\|PILER-CR,CRISPRCasFinder,CRT	1396935-1396968	34	NZ_CP041156	Leisingera aquaemixtae strain R2C4 plasmid unnamed1, complete sequence	69412-69445	8	0.765
NC_014034_5	5.24\|1396935\|34\|NC_014034\|PILER-CR,CRISPRCasFinder,CRT	1396935-1396968	34	NZ_LR536451	Methylocella tundrae isolate MTUNDRAET4 annotated genome plasmid 2	148174-148207	8	0.765
NC_014034_5	5.25\|1397001\|33\|NC_014034\|PILER-CR,CRISPRCasFinder,CRT	1397001-1397033	33	NZ_CP021355	Rhodococcus sp. S2-17 plasmid pRB98, complete sequence	287425-287457	8	0.758
NC_014034_5	5.25\|1397001\|33\|NC_014034\|PILER-CR,CRISPRCasFinder,CRT	1397001-1397033	33	NZ_KX710094	Leclercia adecarboxylata strain P10164 plasmid pP10164-3, complete sequence	73729-73761	8	0.758
NC_014034_5	5.25\|1397001\|33\|NC_014034\|PILER-CR,CRISPRCasFinder,CRT	1397001-1397033	33	NZ_CP040894	Leclercia adecarboxylata strain Z96-1 plasmid pZ96-1_3, complete sequence	25910-25942	8	0.758
NC_014034_5	5.31\|1397400\|34\|NC_014034\|PILER-CR,CRISPRCasFinder,CRT	1397400-1397433	34	NZ_CP021071	Mesorhizobium sp. WSM1497 plasmid pWSM1497, complete sequence	125627-125660	8	0.765
NC_014034_5	5.31\|1397400\|34\|NC_014034\|PILER-CR,CRISPRCasFinder,CRT	1397400-1397433	34	NZ_CP015065	Mesorhizobium ciceri biovar biserrulae strain WSM1284 plasmid pMc1284, complete sequence	155947-155980	8	0.765
NC_014034_5	5.31\|1397400\|34\|NC_014034\|PILER-CR,CRISPRCasFinder,CRT	1397400-1397433	34	NZ_CP015063	Mesorhizobium ciceri strain CC1192 plasmid pMc1192, complete sequence	173660-173693	8	0.765
NC_014034_5	5.31\|1397400\|34\|NC_014034\|PILER-CR,CRISPRCasFinder,CRT	1397400-1397433	34	NC_002682	Mesorhizobium japonicum MAFF 303099 plasmid pMLb, complete sequence	122068-122101	8	0.765
NC_014034_5	5.31\|1397400\|34\|NC_014034\|PILER-CR,CRISPRCasFinder,CRT	1397400-1397433	34	NC_014918	Mesorhizobium ciceri biovar biserrulae WSM1271 plasmid pMESCI01, complete sequence	366095-366128	8	0.765
NC_014034_5	5.34\|1397599\|34\|NC_014034\|PILER-CR,CRISPRCasFinder,CRT	1397599-1397632	34	NZ_CP049732	Rhizobium leguminosarum strain A1 plasmid pRL11, complete sequence	369320-369353	8	0.765
NC_014034_7	7.2\|2157830\|36\|NC_014034\|CRISPRCasFinder	2157830-2157865	36	NZ_CP006991	Rhizobium sp. IE4771 plasmid pRetIE4771e, complete sequence	238917-238952	8	0.778
NC_014034_2	2.2\|1349659\|35\|NC_014034\|PILER-CR	1349659-1349693	35	NZ_CP029357	Azospirillum sp. CFH 70021 plasmid unnamed2	367400-367434	9	0.743
NC_014034_2	2.2\|1349659\|35\|NC_014034\|PILER-CR	1349659-1349693	35	NC_018023	Mycolicibacterium chubuense NBB4 plasmid pMYCCH.02, complete sequence	85771-85805	9	0.743
NC_014034_2	2.2\|1349659\|35\|NC_014034\|PILER-CR	1349659-1349693	35	NZ_CP009439	Streptomyces glaucescens strain GLA.O plasmid pSglau1, complete sequence	151753-151787	9	0.743
NC_014034_3	3.2\|1356407\|32\|NC_014034\|PILER-CR	1356407-1356438	32	NZ_CP024308	Sinorhizobium fredii strain NXT3 plasmid pSfreNXT3a, complete sequence	377771-377802	9	0.719
NC_014034_3	3.2\|1356407\|32\|NC_014034\|PILER-CR	1356407-1356438	32	KR093641	Moraxella phage Mcat17, complete genome	52901-52932	9	0.719
NC_014034_3	3.3\|1356337\|32\|NC_014034\|CRISPRCasFinder	1356337-1356368	32	NZ_CP039965	Pseudorhodobacter sp. S12M18 plasmid unnamed1, complete sequence	325032-325063	9	0.719
NC_014034_5	5.5\|1395665\|34\|NC_014034\|PILER-CR,CRISPRCasFinder,CRT	1395665-1395698	34	NC_014159	Tsukamurella paurometabola DSM 20162 plasmid pTpau01, complete sequence	12274-12307	9	0.735
NC_014034_5	5.5\|1395665\|34\|NC_014034\|PILER-CR,CRISPRCasFinder,CRT	1395665-1395698	34	NZ_CP046100	Rhodococcus sp. AQ5-07 plasmid unnamed1, complete sequence	39488-39521	9	0.735
NC_014034_5	5.13\|1396199\|36\|NC_014034\|PILER-CR,CRISPRCasFinder,CRT	1396199-1396234	36	NZ_AP015031	Pseudomonas putida strain KF715 plasmid pKF715B, complete sequence	183426-183461	9	0.75
NC_014034_5	5.13\|1396199\|36\|NC_014034\|PILER-CR,CRISPRCasFinder,CRT	1396199-1396234	36	NZ_CP044084	Pseudomonas luteola strain FDAARGOS_637 plasmid unnamed1, complete sequence	292973-293008	9	0.75
NC_014034_5	5.16\|1396402\|36\|NC_014034\|PILER-CR,CRISPRCasFinder,CRT	1396402-1396437	36	NZ_LR594677	Variovorax sp. PBS-H4 plasmid 3	50560-50595	9	0.75
NC_014034_5	5.16\|1396402\|36\|NC_014034\|PILER-CR,CRISPRCasFinder,CRT	1396402-1396437	36	NZ_LR594661	Variovorax sp. PBL-H6 plasmid 3	29234-29269	9	0.75
NC_014034_5	5.16\|1396402\|36\|NC_014034\|PILER-CR,CRISPRCasFinder,CRT	1396402-1396437	36	NZ_CP044974	Hydrogenophaga sp. PBL-H3 substr. PBL-H3(B4) plasmid pPBL-H3_B4-2, complete sequence	101544-101579	9	0.75
NC_014034_5	5.16\|1396402\|36\|NC_014034\|PILER-CR,CRISPRCasFinder,CRT	1396402-1396437	36	AP018707	Uncultured bacterium plasmid pSN1104-11 DNA, complete sequence	37770-37805	9	0.75
NC_014034_5	5.16\|1396402\|36\|NC_014034\|PILER-CR,CRISPRCasFinder,CRT	1396402-1396437	36	AP018708	Uncultured bacterium plasmid pSN1104-34 DNA, complete sequence	37854-37889	9	0.75
NC_014034_5	5.16\|1396402\|36\|NC_014034\|PILER-CR,CRISPRCasFinder,CRT	1396402-1396437	36	NZ_CP044977	Hydrogenophaga sp. PBL-H3 substr. PBL-H3(B2) plasmid pPBL-H3_B2-2, complete sequence	104095-104130	9	0.75
NC_014034_5	5.16\|1396402\|36\|NC_014034\|PILER-CR,CRISPRCasFinder,CRT	1396402-1396437	36	NZ_CP044551	Hydrogenophaga sp. BPS33 plasmid pBPS33-2, complete sequence	103615-103650	9	0.75
NC_014034_5	5.19\|1396605\|34\|NC_014034\|PILER-CR,CRISPRCasFinder,CRT	1396605-1396638	34	NZ_CP036297	Planctomycetes bacterium Pla86 plasmid pPla86_1, complete sequence	35247-35280	9	0.735
NC_014034_5	5.19\|1396605\|34\|NC_014034\|PILER-CR,CRISPRCasFinder,CRT	1396605-1396638	34	NZ_CP036288	Planctomycetes bacterium Pla133 plasmid pPla133_1, complete sequence	35277-35310	9	0.735
NC_014034_5	5.24\|1396935\|34\|NC_014034\|PILER-CR,CRISPRCasFinder,CRT	1396935-1396968	34	NZ_CP026091	Ralstonia solanacearum strain IBSBF 2570 plasmid unnamed, complete sequence	1118128-1118161	9	0.735
NC_014034_5	5.24\|1396935\|34\|NC_014034\|PILER-CR,CRISPRCasFinder,CRT	1396935-1396968	34	NC_014309	Ralstonia solanacearum CFBP2957 plasmid RCFBPv3_mp, complete genome	792471-792504	9	0.735
NC_014034_5	5.24\|1396935\|34\|NC_014034\|PILER-CR,CRISPRCasFinder,CRT	1396935-1396968	34	NZ_CP026093	Ralstonia solanacearum strain SFC plasmid unnamed, complete sequence	1118249-1118282	9	0.735
NC_014034_5	5.24\|1396935\|34\|NC_014034\|PILER-CR,CRISPRCasFinder,CRT	1396935-1396968	34	NZ_CP021767	Ralstonia solanacearum strain RS 489 plasmid unnamed, complete sequence	842348-842381	9	0.735
NC_014034_5	5.24\|1396935\|34\|NC_014034\|PILER-CR,CRISPRCasFinder,CRT	1396935-1396968	34	NZ_CP021653	Ralstonia solanacearum strain RS 488 plasmid unnamed, complete sequence	842340-842373	9	0.735
NC_014034_5	5.24\|1396935\|34\|NC_014034\|PILER-CR,CRISPRCasFinder,CRT	1396935-1396968	34	NZ_CP012688	Ralstonia solanacearum strain UY031 plasmid unnamed, complete sequence	842347-842380	9	0.735
NC_014034_5	5.24\|1396935\|34\|NC_014034\|PILER-CR,CRISPRCasFinder,CRT	1396935-1396968	34	CP047139	Ralstonia solanacearum strain CFBP 8695 plasmid unnamed, complete sequence	850806-850839	9	0.735
NC_014034_5	5.24\|1396935\|34\|NC_014034\|PILER-CR,CRISPRCasFinder,CRT	1396935-1396968	34	CP047137	Ralstonia solanacearum strain CFBP 8697 plasmid unnamed, complete sequence	814052-814085	9	0.735
NC_014034_5	5.25\|1397001\|33\|NC_014034\|PILER-CR,CRISPRCasFinder,CRT	1397001-1397033	33	NC_003903	Streptomyces coelicolor A3(2) plasmid SCP1, complete sequence	122300-122332	9	0.727
NC_014034_5	5.25\|1397001\|33\|NC_014034\|PILER-CR,CRISPRCasFinder,CRT	1397001-1397033	33	NZ_CP046573	Rhodococcus sp. WAY2 plasmid pRWAY01, complete sequence	23579-23611	9	0.727
NC_014034_5	5.28\|1397199\|35\|NC_014034\|PILER-CR,CRISPRCasFinder,CRT	1397199-1397233	35	NZ_CP018096	Chelatococcus daeguensis strain TAD1 plasmid pTAD1, complete sequence	448768-448802	9	0.743
NC_014034_5	5.33\|1397532\|35\|NC_014034\|PILER-CR,CRISPRCasFinder,CRT	1397532-1397566	35	NC_006362	Nocardia farcinica IFM 10152 plasmid pNF1, complete sequence	59770-59804	9	0.743
NC_014034_2	2.2\|1349659\|35\|NC_014034\|PILER-CR	1349659-1349693	35	NZ_CP011665	Streptomyces sp. Mg1 plasmid pSMg1-1, complete sequence	71977-72011	10	0.714
NC_014034_5	5.5\|1395665\|34\|NC_014034\|PILER-CR,CRISPRCasFinder,CRT	1395665-1395698	34	NZ_LN832562	Paracoccus aminovorans isolate JCM7685 plasmid IV, complete sequence	419120-419153	10	0.706
NC_014034_5	5.22\|1396803\|33\|NC_014034\|PILER-CR,CRISPRCasFinder,CRT	1396803-1396835	33	NZ_CP026653	Streptomyces dengpaensis strain XZHG99 plasmid unnamed1, complete sequence	13931-13963	10	0.697
NC_014034_5	5.24\|1396935\|34\|NC_014034\|PILER-CR,CRISPRCasFinder,CRT	1396935-1396968	34	NZ_CP022775	Ralstonia solanacearum strain T12 plasmid unnamed, complete sequence	684048-684081	10	0.706
NC_014034_5	5.24\|1396935\|34\|NC_014034\|PILER-CR,CRISPRCasFinder,CRT	1396935-1396968	34	NZ_CP022762	Ralstonia solanacearum strain T95 plasmid unnamed, complete sequence	579412-579445	10	0.706
NC_014034_5	5.24\|1396935\|34\|NC_014034\|PILER-CR,CRISPRCasFinder,CRT	1396935-1396968	34	NZ_CP037902	Cupriavidus metallidurans strain BS1 plasmid p1, complete sequence	341427-341460	10	0.706
NC_014034_5	5.24\|1396935\|34\|NC_014034\|PILER-CR,CRISPRCasFinder,CRT	1396935-1396968	34	NZ_CP007129	Gemmatirosa kalamazoonesis strain KBS708 plasmid 1, complete sequence	390765-390798	10	0.706
NC_014034_5	5.24\|1396935\|34\|NC_014034\|PILER-CR,CRISPRCasFinder,CRT	1396935-1396968	34	NZ_CP046332	Cupriavidus metallidurans strain FDAARGOS_675 plasmid unnamed2	207019-207052	10	0.706
NC_014034_5	5.24\|1396935\|34\|NC_014034\|PILER-CR,CRISPRCasFinder,CRT	1396935-1396968	34	NZ_CP026546	Cupriavidus metallidurans strain Ni-2 plasmid unnamed2	191498-191531	10	0.706
NC_014034_5	5.24\|1396935\|34\|NC_014034\|PILER-CR,CRISPRCasFinder,CRT	1396935-1396968	34	NZ_CP023017	Ralstonia solanacearum strain SL3022 plasmid unnamed, complete sequence	638236-638269	10	0.706
NC_014034_5	5.24\|1396935\|34\|NC_014034\|PILER-CR,CRISPRCasFinder,CRT	1396935-1396968	34	NZ_CP014703	Ralstonia solanacearum strain KACC 10722 plasmid, complete sequence	578527-578560	10	0.706
NC_014034_5	5.24\|1396935\|34\|NC_014034\|PILER-CR,CRISPRCasFinder,CRT	1396935-1396968	34	NZ_CP022771	Ralstonia solanacearum strain T51 plasmid unnamed, complete sequence	579400-579433	10	0.706
NC_014034_5	5.24\|1396935\|34\|NC_014034\|PILER-CR,CRISPRCasFinder,CRT	1396935-1396968	34	NZ_CP022777	Ralstonia solanacearum strain T11 plasmid unnamed, complete sequence	579419-579452	10	0.706
NC_014034_5	5.24\|1396935\|34\|NC_014034\|PILER-CR,CRISPRCasFinder,CRT	1396935-1396968	34	NZ_CP022799	Ralstonia solanacearum strain SL2064 plasmid unnamed, complete sequence	579397-579430	10	0.706
NC_014034_5	5.24\|1396935\|34\|NC_014034\|PILER-CR,CRISPRCasFinder,CRT	1396935-1396968	34	NZ_CP022764	Ralstonia solanacearum strain T82 plasmid unnamed, complete sequence	684106-684139	10	0.706
NC_014034_5	5.24\|1396935\|34\|NC_014034\|PILER-CR,CRISPRCasFinder,CRT	1396935-1396968	34	NZ_CP022797	Ralstonia solanacearum strain SL2312 plasmid unnamed, complete sequence	684106-684139	10	0.706
NC_014034_5	5.24\|1396935\|34\|NC_014034\|PILER-CR,CRISPRCasFinder,CRT	1396935-1396968	34	NC_006466	Cupriavidus metallidurans CH34 plasmid pMOL30, complete sequence	215723-215756	10	0.706
NC_014034_5	5.24\|1396935\|34\|NC_014034\|PILER-CR,CRISPRCasFinder,CRT	1396935-1396968	34	NZ_CP043439	Cupriavidus campinensis strain MJ1 plasmid unnamed2, complete sequence	308189-308222	10	0.706
NC_014034_5	5.24\|1396935\|34\|NC_014034\|PILER-CR,CRISPRCasFinder,CRT	1396935-1396968	34	NZ_CP022758	Ralstonia solanacearum strain T101 plasmid unnamed, complete sequence	684095-684128	10	0.706
NC_014034_5	5.33\|1397532\|35\|NC_014034\|PILER-CR,CRISPRCasFinder,CRT	1397532-1397566	35	NC_022049	Paracoccus aminophilus JCM 7686 plasmid pAMI4, complete sequence	28662-28696	10	0.714
NC_014034_5	5.34\|1397599\|34\|NC_014034\|PILER-CR,CRISPRCasFinder,CRT	1397599-1397632	34	NZ_CP012748	Paraburkholderia caribensis MBA4 plasmid unnamed, complete sequence	933669-933702	10	0.706
NC_014034_5	5.24\|1396935\|34\|NC_014034\|PILER-CR,CRISPRCasFinder,CRT	1396935-1396968	34	NZ_CP039912	Agrobacterium tumefaciens strain CFBP6625 plasmid pAtCFBP6625a, complete sequence	269179-269212	11	0.676
NC_014034_5	5.25\|1397001\|33\|NC_014034\|PILER-CR,CRISPRCasFinder,CRT	1397001-1397033	33	CP054928	Streptomyces fulvissimus strain NA06532 plasmid unnamed2, complete sequence	51251-51283	11	0.667
NC_014034_5	5.19\|1396605\|34\|NC_014034\|PILER-CR,CRISPRCasFinder,CRT	1396605-1396638	34	MG592644	Vibrio phage 1.276.O._10N.286.54.E4, partial genome	10881-10914	12	0.647
NC_014034_5	5.19\|1396605\|34\|NC_014034\|PILER-CR,CRISPRCasFinder,CRT	1396605-1396638	34	MG592567	Vibrio phage 1.198.A._10N.286.54.F4, partial genome	12280-12313	12	0.647
NC_014034_5	5.19\|1396605\|34\|NC_014034\|PILER-CR,CRISPRCasFinder,CRT	1396605-1396638	34	MG592568	Vibrio phage 1.198.B._10N.286.54.F4, partial genome	12280-12313	12	0.647

1. spacer 5.6|1395731|33|NC_014034|PILER-CR,CRISPRCasFinder,CRT matches to NC_020489 (Rhodobacter phage RcapNL, complete genome) position: , mismatch: 0, identity: 1.0

tggtatggatctggcgcaaacggaaagtctgtc	CRISPR spacer
tggtatggatctggcgcaaacggaaagtctgtc	Protospacer
*********************************

2. spacer 5.6|1395731|33|NC_014034|PILER-CR,CRISPRCasFinder,CRT matches to JF974309 (Rhodobacter phage RcNL1, *** SEQUENCING IN PROGRESS ***, 5 unordered pieces) position: , mismatch: 0, identity: 1.0

tggtatggatctggcgcaaacggaaagtctgtc	CRISPR spacer
tggtatggatctggcgcaaacggaaagtctgtc	Protospacer
*********************************

3. spacer 5.35|1397665|35|NC_014034|PILER-CR,CRISPRCasFinder,CRT matches to NC_020489 (Rhodobacter phage RcapNL, complete genome) position: , mismatch: 0, identity: 1.0

tacagagttccggtcttgttctgttccggtaacag	CRISPR spacer
tacagagttccggtcttgttctgttccggtaacag	Protospacer
***********************************

4. spacer 5.35|1397665|35|NC_014034|PILER-CR,CRISPRCasFinder,CRT matches to JF974309 (Rhodobacter phage RcNL1, *** SEQUENCING IN PROGRESS ***, 5 unordered pieces) position: , mismatch: 0, identity: 1.0

tacagagttccggtcttgttctgttccggtaacag	CRISPR spacer
tacagagttccggtcttgttctgttccggtaacag	Protospacer
***********************************

5. spacer 5.38|1397868|35|NC_014034|PILER-CR,CRISPRCasFinder,CRT matches to NC_020489 (Rhodobacter phage RcapNL, complete genome) position: , mismatch: 0, identity: 1.0

ccggcacctcagccccgcccgctgtctcaccaaca	CRISPR spacer
ccggcacctcagccccgcccgctgtctcaccaaca	Protospacer
***********************************

6. spacer 5.38|1397868|35|NC_014034|PILER-CR,CRISPRCasFinder,CRT matches to JF974309 (Rhodobacter phage RcNL1, *** SEQUENCING IN PROGRESS ***, 5 unordered pieces) position: , mismatch: 0, identity: 1.0

ccggcacctcagccccgcccgctgtctcaccaaca	CRISPR spacer
ccggcacctcagccccgcccgctgtctcaccaaca	Protospacer
***********************************

7. spacer 5.9|1395931|34|NC_014034|PILER-CR,CRISPRCasFinder,CRT matches to NC_020489 (Rhodobacter phage RcapNL, complete genome) position: , mismatch: 1, identity: 0.971

gatgcgttcatggcctacgtcgggcagtggactg	CRISPR spacer
gacgcgttcatggcctacgtcgggcagtggactg	Protospacer
**.*******************************

8. spacer 5.9|1395931|34|NC_014034|PILER-CR,CRISPRCasFinder,CRT matches to JF974309 (Rhodobacter phage RcNL1, *** SEQUENCING IN PROGRESS ***, 5 unordered pieces) position: , mismatch: 1, identity: 0.971

gatgcgttcatggcctacgtcgggcagtggactg	CRISPR spacer
gacgcgttcatggcctacgtcgggcagtggactg	Protospacer
**.*******************************

9. spacer 5.16|1396402|36|NC_014034|PILER-CR,CRISPRCasFinder,CRT matches to NC_020489 (Rhodobacter phage RcapNL, complete genome) position: , mismatch: 1, identity: 0.972

cgcgccctgcgggtgatggcgacgggcaccacggcg	CRISPR spacer
cgcgccatgcgggtgatggcgacgggcaccacggcg	Protospacer
****** *****************************

10. spacer 5.16|1396402|36|NC_014034|PILER-CR,CRISPRCasFinder,CRT matches to JF974309 (Rhodobacter phage RcNL1, *** SEQUENCING IN PROGRESS ***, 5 unordered pieces) position: , mismatch: 1, identity: 0.972

cgcgccctgcgggtgatggcgacgggcaccacggcg	CRISPR spacer
cgcgccatgcgggtgatggcgacgggcaccacggcg	Protospacer
****** *****************************

11. spacer 5.11|1396064|35|NC_014034|PILER-CR,CRISPRCasFinder,CRT matches to NC_020489 (Rhodobacter phage RcapNL, complete genome) position: , mismatch: 2, identity: 0.943

aggcgcatctgatgtatatgcccggtgagacggct	CRISPR spacer
gggcgcatcggatgtatatgcccggtgagacggct	Protospacer
.******** *************************

12. spacer 5.11|1396064|35|NC_014034|PILER-CR,CRISPRCasFinder,CRT matches to JF974309 (Rhodobacter phage RcNL1, *** SEQUENCING IN PROGRESS ***, 5 unordered pieces) position: , mismatch: 2, identity: 0.943

aggcgcatctgatgtatatgcccggtgagacggct	CRISPR spacer
gggcgcatcggatgtatatgcccggtgagacggct	Protospacer
.******** *************************

13. spacer 6.2|1434382|33|NC_014034|CRT,PILER-CR,CRISPRCasFinder matches to NC_020489 (Rhodobacter phage RcapNL, complete genome) position: , mismatch: 2, identity: 0.939

gtctccgctctgcttcacggctgcgtcaacctt	CRISPR spacer
gtcgccgctctgcttcatggctgcgtcaacctt	Protospacer
*** *************.***************

14. spacer 6.2|1434382|33|NC_014034|CRT,PILER-CR,CRISPRCasFinder matches to JF974309 (Rhodobacter phage RcNL1, *** SEQUENCING IN PROGRESS ***, 5 unordered pieces) position: , mismatch: 2, identity: 0.939

gtctccgctctgcttcacggctgcgtcaacctt	CRISPR spacer
gtcgccgctctgcttcatggctgcgtcaacctt	Protospacer
*** *************.***************

15. spacer 6.5|1434579|35|NC_014034|CRT,PILER-CR,CRISPRCasFinder matches to NC_016165 (Rhodobacter phage RcapMu, complete genome) position: , mismatch: 2, identity: 0.943

gacgcgctgaaggagggtgatctcggtggcgcctt	CRISPR spacer
gacgcgctgaaggaaggtgatcttggtggcgcctt	Protospacer
**************.********.***********

16. spacer 6.5|1434579|35|NC_014034|CRT,PILER-CR,CRISPRCasFinder matches to JF974309 (Rhodobacter phage RcNL1, *** SEQUENCING IN PROGRESS ***, 5 unordered pieces) position: , mismatch: 2, identity: 0.943

gacgcgctgaaggagggtgatctcggtggcgcctt	CRISPR spacer
gacgcgctgaaggaaggtgatcttggtggcgcctt	Protospacer
**************.********.***********

17. spacer 6.8|1434778|35|NC_014034|CRT,PILER-CR,CRISPRCasFinder matches to NC_016165 (Rhodobacter phage RcapMu, complete genome) position: , mismatch: 2, identity: 0.943

gacgcgctgaaggagggtgatctcggtggcgcctt	CRISPR spacer
gacgcgctgaaggaaggtgatcttggtggcgcctt	Protospacer
**************.********.***********

18. spacer 6.8|1434778|35|NC_014034|CRT,PILER-CR,CRISPRCasFinder matches to JF974309 (Rhodobacter phage RcNL1, *** SEQUENCING IN PROGRESS ***, 5 unordered pieces) position: , mismatch: 2, identity: 0.943

gacgcgctgaaggagggtgatctcggtggcgcctt	CRISPR spacer
gacgcgctgaaggaaggtgatcttggtggcgcctt	Protospacer
**************.********.***********

19. spacer 2.2|1349659|35|NC_014034|PILER-CR matches to NZ_CP049788 (Ralstonia solanacearum strain B2 plasmid unnamed, complete sequence) position: , mismatch: 6, identity: 0.829

-acgggggcggcggcgaggcaggcgaaggcggcggc	CRISPR spacer
agcaggggc-tcggcgaggccgacgaaggcggcggc	Protospacer
 .*.*****  ********* *.*************

20. spacer 2.2|1349659|35|NC_014034|PILER-CR matches to CP023013 (Ralstonia solanacearum strain T110 plasmid unnamed, complete sequence) position: , mismatch: 6, identity: 0.829

-acgggggcggcggcgaggcaggcgaaggcggcggc	CRISPR spacer
agcaggggc-tcggcgaggccgacgaaggcggcggc	Protospacer
 .*.*****  ********* *.*************

21. spacer 2.2|1349659|35|NC_014034|PILER-CR matches to NZ_CP022783 (Ralstonia solanacearum strain SL3755 plasmid unnamed, complete sequence) position: , mismatch: 6, identity: 0.829

-acgggggcggcggcgaggcaggcgaaggcggcggc	CRISPR spacer
agcaggggc-tcggcgaggccgacgaaggcggcggc	Protospacer
 .*.*****  ********* *.*************

22. spacer 2.2|1349659|35|NC_014034|PILER-CR matches to NZ_CP022795 (Ralstonia solanacearum strain SL2330 plasmid unnamed, complete sequence) position: , mismatch: 6, identity: 0.829

-acgggggcggcggcgaggcaggcgaaggcggcggc	CRISPR spacer
agcaggggc-tcggcgaggccgacgaaggcggcggc	Protospacer
 .*.*****  ********* *.*************

23. spacer 5.24|1396935|34|NC_014034|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP032348 (Azospirillum brasilense strain MTCC4039 plasmid p4, complete sequence) position: , mismatch: 6, identity: 0.824

agcctgcgcggccgcatcggcttccgcctgcgtg	CRISPR spacer
tgcctgcgcggccgcatcgccttccgcgtgaaag	Protospacer
 ****************** ******* ** . *

24. spacer 5.24|1396935|34|NC_014034|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP015740 (Shinella sp. HZN7 plasmid pShin-04, complete sequence) position: , mismatch: 6, identity: 0.824

-agcctgcgcggccgcatcggcttccgcctgcgtg	CRISPR spacer
gagcgtgc-cgtccgcatcggcttgcgcctgcgac	Protospacer
 *** *** ** ************ ********

25. spacer 5.28|1397199|35|NC_014034|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP012399 (Chelatococcus sp. CO-6 plasmid pCO-6, complete sequence) position: , mismatch: 6, identity: 0.829

gtgtctgcc-acgacgccctgcaccagatccgcgcc	CRISPR spacer
-tctcggccttcgacgcgctgcagcagatccgcgcc	Protospacer
 * ** ***  ****** ***** ************

26. spacer 5.33|1397532|35|NC_014034|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP016083 (Streptomyces sp. SAT1 plasmid unnamed3, complete sequence) position: , mismatch: 6, identity: 0.829

--aacccgatcatggcccgcctcagcgccgcgctgac	CRISPR spacer
ctgaccc--tgatggtcggcctcagcgccgcgctgac	Protospacer
  .****  * ****.* *******************

27. spacer 7.6|2157833|33|NC_014034|CRT,PILER-CR matches to NZ_CP013555 (Rhizobium phaseoli strain N931 plasmid pRphaN931c, complete sequence) position: , mismatch: 6, identity: 0.818

tctcccagcataccaaaccgctggcgaccatca	CRISPR spacer
cgtcccagcaaaccaacccgctggcgaccaacg	Protospacer
. ******** ***** ************* *.

28. spacer 7.6|2157833|33|NC_014034|CRT,PILER-CR matches to NZ_CP013578 (Rhizobium phaseoli strain N671 plasmid pRphaN671d, complete sequence) position: , mismatch: 6, identity: 0.818

tctcccagcataccaaaccgctggcgaccatca	CRISPR spacer
cgtcccagcaaaccaacccgctggcgaccaacg	Protospacer
. ******** ***** ************* *.

29. spacer 7.6|2157833|33|NC_014034|CRT,PILER-CR matches to NZ_CP013566 (Rhizobium phaseoli strain N831 plasmid pRphaN831c, complete sequence) position: , mismatch: 6, identity: 0.818

tctcccagcataccaaaccgctggcgaccatca	CRISPR spacer
cgtcccagcaaaccaacccgctggcgaccaacg	Protospacer
. ******** ***** ************* *.

30. spacer 7.6|2157833|33|NC_014034|CRT,PILER-CR matches to NZ_CP013572 (Rhizobium phaseoli strain N771 plasmid pRphaN671d, complete sequence) position: , mismatch: 6, identity: 0.818

tctcccagcataccaaaccgctggcgaccatca	CRISPR spacer
cgtcccagcaaaccaacccgctggcgaccaacg	Protospacer
. ******** ***** ************* *.

31. spacer 2.2|1349659|35|NC_014034|PILER-CR matches to NZ_AP022593 (Mycolicibacterium arabiense strain JCM 18538 plasmid pJCM18538, complete sequence) position: , mismatch: 7, identity: 0.8

acgggggcggcggcgaggcaggcgaaggcggcggc	CRISPR spacer
gcggccgatgcggcgaggcaggcggaggcggcggg	Protospacer
.***  *  ***************.*********

32. spacer 5.24|1396935|34|NC_014034|PILER-CR,CRISPRCasFinder,CRT matches to CP054924 (Verrucosispora sp. NA02020 plasmid unnamed, complete sequence) position: , mismatch: 7, identity: 0.794

agcctgcgcggccgcatcggcttccgcctgcgtg	CRISPR spacer
cgtccgcgccgccgcctcggcttccgcctgcgcc	Protospacer
 *.*.**** ***** ****************.

33. spacer 5.24|1396935|34|NC_014034|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP017947 (Bosea sp. Tri-49 plasmid unnamed1, complete sequence) position: , mismatch: 7, identity: 0.794

agcctg--cgcggccgcatcggcttccgcctgcgtg	CRISPR spacer
--cccggccgcggcggcatcggctgccgcctgccgg	Protospacer
  **.*  ****** ********* ********  *

34. spacer 5.24|1396935|34|NC_014034|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP039340 (Ralstonia solanacearum strain UW386 plasmid pUW386, complete sequence) position: , mismatch: 7, identity: 0.794

agcctgcgcggccgcatcggcttccgcctgcgtg	CRISPR spacer
agactgcgcggtcgcatcggcttcacgcgccgtg	Protospacer
** ********.************   *  ****

35. spacer 5.33|1397532|35|NC_014034|PILER-CR,CRISPRCasFinder,CRT matches to NZ_AP014705 (Methylobacterium aquaticum strain MA-22A plasmid pMaq22A_1p, complete sequence) position: , mismatch: 7, identity: 0.8

aacccgat---catggcccgcctcagcgccgcgctgac	CRISPR spacer
---ccggccgacatggcccggctcatcgccgcgctgac	Protospacer
   ***..   ********* **** ************

36. spacer 7.2|2157830|36|NC_014034|CRISPRCasFinder matches to NZ_CP013555 (Rhizobium phaseoli strain N931 plasmid pRphaN931c, complete sequence) position: , mismatch: 7, identity: 0.806

ggctctcccagcataccaaaccgctggcgaccatca	CRISPR spacer
ggacgtcccagcaaaccaacccgctggcgaccaacg	Protospacer
** . ******** ***** ************* *.

37. spacer 7.2|2157830|36|NC_014034|CRISPRCasFinder matches to NZ_CP013578 (Rhizobium phaseoli strain N671 plasmid pRphaN671d, complete sequence) position: , mismatch: 7, identity: 0.806

ggctctcccagcataccaaaccgctggcgaccatca	CRISPR spacer
ggacgtcccagcaaaccaacccgctggcgaccaacg	Protospacer
** . ******** ***** ************* *.

38. spacer 7.2|2157830|36|NC_014034|CRISPRCasFinder matches to NZ_CP013566 (Rhizobium phaseoli strain N831 plasmid pRphaN831c, complete sequence) position: , mismatch: 7, identity: 0.806

ggctctcccagcataccaaaccgctggcgaccatca	CRISPR spacer
ggacgtcccagcaaaccaacccgctggcgaccaacg	Protospacer
** . ******** ***** ************* *.

39. spacer 7.2|2157830|36|NC_014034|CRISPRCasFinder matches to NZ_CP013572 (Rhizobium phaseoli strain N771 plasmid pRphaN671d, complete sequence) position: , mismatch: 7, identity: 0.806

ggctctcccagcataccaaaccgctggcgaccatca	CRISPR spacer
ggacgtcccagcaaaccaacccgctggcgaccaacg	Protospacer
** . ******** ***** ************* *.

40. spacer 7.6|2157833|33|NC_014034|CRT,PILER-CR matches to NZ_CP006991 (Rhizobium sp. IE4771 plasmid pRetIE4771e, complete sequence) position: , mismatch: 7, identity: 0.788

tctcccagcataccaaaccgctggcgaccatca	CRISPR spacer
cgtcccagcaaaccaacccgctggcgaccaatg	Protospacer
. ******** ***** ************* ..

41. spacer 7.7|2157903|31|NC_014034|CRT matches to NZ_CP021084 (Deinococcus ficus strain CC-FR2-10 plasmid pDFI3, complete sequence) position: , mismatch: 7, identity: 0.774

acaggagagaccgatgaaaatcacggccttc	CRISPR spacer
ccaggagagaccgatgaaaaacacctcgtgg	Protospacer
 ******************* ***  * *

42. spacer 2.2|1349659|35|NC_014034|PILER-CR matches to NZ_CP041652 (Streptomyces sp. RLB1-9 plasmid pRLB1-9.2, complete sequence) position: , mismatch: 8, identity: 0.771

acgggggcggcggcgaggcaggcgaaggcggcggc	CRISPR spacer
acggggacggcggccaggcaggcgagtacgacgag	Protospacer
******.******* **********. .**.**.

43. spacer 3.1|1356338|31|NC_014034|PILER-CR matches to NZ_CP039965 (Pseudorhodobacter sp. S12M18 plasmid unnamed1, complete sequence) position: , mismatch: 8, identity: 0.742

cccagaac---aggtgtttgagcggcccacccgc	CRISPR spacer
---ggggcgcaaggtgtttgaccgccccacccgc	Protospacer
   .*..*   ********** ** *********

44. spacer 5.24|1396935|34|NC_014034|PILER-CR,CRISPRCasFinder,CRT matches to NC_009620 (Sinorhizobium medicae WSM419 plasmid pSMED01, complete sequence) position: , mismatch: 8, identity: 0.765

agcctgcgcggccgcatcggcttccgcctgcgtg	CRISPR spacer
cgccggcgcggccgcatcgacttccgccttgaga	Protospacer
 *** **************.*********  . .

45. spacer 5.24|1396935|34|NC_014034|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP012940 (Ralstonia solanacearum strain UW163 plasmid unnamed, complete sequence) position: , mismatch: 8, identity: 0.765

agcctgcgcggccgcatcggcttccgcctgcgtg	CRISPR spacer
cgcgcggaccgccgcgtcgacttccgcctgcgtg	Protospacer
 ** .* .* *****.***.**************

46. spacer 5.24|1396935|34|NC_014034|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP012944 (Ralstonia solanacearum strain IBSBF1503 plasmid unnamed, complete sequence) position: , mismatch: 8, identity: 0.765

agcctgcgcggccgcatcggcttccgcctgcgtg	CRISPR spacer
cgcgcggaccgccgcgtcgacttccgcctgcgtg	Protospacer
 ** .* .* *****.***.**************

47. spacer 5.24|1396935|34|NC_014034|PILER-CR,CRISPRCasFinder,CRT matches to NC_017575 (Ralstonia solanacearum Po82 megaplasmid, complete sequence) position: , mismatch: 8, identity: 0.765

agcctgcgcggccgcatcggcttccgcctgcgtg	CRISPR spacer
cgcgcggaccgccgcgtcgacttccgcctgcgtg	Protospacer
 ** .* .* *****.***.**************

48. spacer 5.24|1396935|34|NC_014034|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP026308 (Ralstonia solanacearum strain IBSBF 2571 plasmid unnamed, complete sequence) position: , mismatch: 8, identity: 0.765

agcctgcgcggccgcatcggcttccgcctgcgtg	CRISPR spacer
cgcgcggaccgccgcgtcgacttccgcctgcgtg	Protospacer
 ** .* .* *****.***.**************

49. spacer 5.24|1396935|34|NC_014034|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP051295 (Ralstonia solanacearum strain CIAT_078 plasmid megaplasmid, complete sequence) position: , mismatch: 8, identity: 0.765

agcctgcgcggccgcatcggcttccgcctgcgtg	CRISPR spacer
cgcgcggaccgccgcgtcgacttccgcctgcgtg	Protospacer
 ** .* .* *****.***.**************

50. spacer 5.24|1396935|34|NC_014034|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP041156 (Leisingera aquaemixtae strain R2C4 plasmid unnamed1, complete sequence) position: , mismatch: 8, identity: 0.765

agcctgcgcggccgcatcggcttccgcctgcgtg	CRISPR spacer
tgcgagcgcggccgcggcggcttccgcctgaccg	Protospacer
 **  **********. *************  .*

51. spacer 5.24|1396935|34|NC_014034|PILER-CR,CRISPRCasFinder,CRT matches to NZ_LR536451 (Methylocella tundrae isolate MTUNDRAET4 annotated genome plasmid 2) position: , mismatch: 8, identity: 0.765

agcctgcgcggccgcatcggcttccgcctgcgtg	CRISPR spacer
aacgagcgcggccgcagcggcctccgcctgagcc	Protospacer
*.*  *********** ****.******** *.

52. spacer 5.25|1397001|33|NC_014034|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP021355 (Rhodococcus sp. S2-17 plasmid pRB98, complete sequence) position: , mismatch: 8, identity: 0.758

atcagctcgtcgttggtcagccggacgatgtcc	CRISPR spacer
gcgaagtagtcgttggtcagccggaagttgtcc	Protospacer
.. *. * ***************** * *****

53. spacer 5.25|1397001|33|NC_014034|PILER-CR,CRISPRCasFinder,CRT matches to NZ_KX710094 (Leclercia adecarboxylata strain P10164 plasmid pP10164-3, complete sequence) position: , mismatch: 8, identity: 0.758

atcagctcgtcgttggtcagccggacgatgtcc----	CRISPR spacer
atcagctcgtcattggtcagcggg----tgctcttta	Protospacer
***********.********* **    **..*

54. spacer 5.25|1397001|33|NC_014034|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP040894 (Leclercia adecarboxylata strain Z96-1 plasmid pZ96-1_3, complete sequence) position: , mismatch: 8, identity: 0.758

atcagctcgtcgttggtcagccggacgatgtcc----	CRISPR spacer
atcagctcgtcattggtcagcggg----tgctcttta	Protospacer
***********.********* **    **..*

55. spacer 5.31|1397400|34|NC_014034|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP021071 (Mesorhizobium sp. WSM1497 plasmid pWSM1497, complete sequence) position: , mismatch: 8, identity: 0.765

tcttcaatggatatggcaaaaccgtccgcgacat	CRISPR spacer
tggcctttggacatgccaaaaccgtccgcgacct	Protospacer
*  .*  ****.*** **************** *

56. spacer 5.31|1397400|34|NC_014034|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP015065 (Mesorhizobium ciceri biovar biserrulae strain WSM1284 plasmid pMc1284, complete sequence) position: , mismatch: 8, identity: 0.765

tcttcaatggatatggcaaaaccgtccgcgacat	CRISPR spacer
tggcctttggacatgccaaaaccgtccgcgacct	Protospacer
*  .*  ****.*** **************** *

57. spacer 5.31|1397400|34|NC_014034|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP015063 (Mesorhizobium ciceri strain CC1192 plasmid pMc1192, complete sequence) position: , mismatch: 8, identity: 0.765

tcttcaatggatatggcaaaaccgtccgcgacat	CRISPR spacer
tggcctttggacatgccaaaaccgtccgcgacct	Protospacer
*  .*  ****.*** **************** *

58. spacer 5.31|1397400|34|NC_014034|PILER-CR,CRISPRCasFinder,CRT matches to NC_002682 (Mesorhizobium japonicum MAFF 303099 plasmid pMLb, complete sequence) position: , mismatch: 8, identity: 0.765

tcttcaatggatatggcaaaaccgtccgcgacat	CRISPR spacer
tgacccttggacatgccaaaaccgtccgcgacct	Protospacer
*  .*  ****.*** **************** *

59. spacer 5.31|1397400|34|NC_014034|PILER-CR,CRISPRCasFinder,CRT matches to NC_014918 (Mesorhizobium ciceri biovar biserrulae WSM1271 plasmid pMESCI01, complete sequence) position: , mismatch: 8, identity: 0.765

tcttcaatggatatggcaaaaccgtccgcgacat	CRISPR spacer
tggcctttggacatgccaaaaccgtccgcgacct	Protospacer
*  .*  ****.*** **************** *

60. spacer 5.34|1397599|34|NC_014034|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP049732 (Rhizobium leguminosarum strain A1 plasmid pRL11, complete sequence) position: , mismatch: 8, identity: 0.765

atccgcggatcggcgtgacccgccccgcccatcg	CRISPR spacer
atccgcggatctgcgagacccgccacccgcctta	Protospacer
*********** *** ******** * * * *..

61. spacer 7.2|2157830|36|NC_014034|CRISPRCasFinder matches to NZ_CP006991 (Rhizobium sp. IE4771 plasmid pRetIE4771e, complete sequence) position: , mismatch: 8, identity: 0.778

ggctctcccagcataccaaaccgctggcgaccatca	CRISPR spacer
ggacgtcccagcaaaccaacccgctggcgaccaatg	Protospacer
** . ******** ***** ************* ..

62. spacer 2.2|1349659|35|NC_014034|PILER-CR matches to NZ_CP029357 (Azospirillum sp. CFH 70021 plasmid unnamed2) position: , mismatch: 9, identity: 0.743

acgggggcggcggcgaggcaggcgaaggcggcggc	CRISPR spacer
gcgaaggcggcggcgacgccggcgaaggcgcagag	Protospacer
.**..*********** ** **********  *.

63. spacer 2.2|1349659|35|NC_014034|PILER-CR matches to NC_018023 (Mycolicibacterium chubuense NBB4 plasmid pMYCCH.02, complete sequence) position: , mismatch: 9, identity: 0.743

acgggggcggcggcgaggcaggcgaaggcggcggc	CRISPR spacer
actatctcggcggcgaggcgggcgtaggcggccac	Protospacer
** .   ************.**** ******* .*

64. spacer 2.2|1349659|35|NC_014034|PILER-CR matches to NZ_CP009439 (Streptomyces glaucescens strain GLA.O plasmid pSglau1, complete sequence) position: , mismatch: 9, identity: 0.743

acgggggcggcggcgaggcaggcgaaggcggcggc	CRISPR spacer
atgagggcggcggcgaggccgacgaaggccaggaa	Protospacer
*.*.*************** *.******* . *.

65. spacer 3.2|1356407|32|NC_014034|PILER-CR matches to NZ_CP024308 (Sinorhizobium fredii strain NXT3 plasmid pSfreNXT3a, complete sequence) position: , mismatch: 9, identity: 0.719

aatgacagcaacgtacagcatcgtttgccttt	CRISPR spacer
tttgactgcaacgtaccgcatcgttgggcggg	Protospacer
  **** ********* ******** * *

66. spacer 3.2|1356407|32|NC_014034|PILER-CR matches to KR093641 (Moraxella phage Mcat17, complete genome) position: , mismatch: 9, identity: 0.719

aatgacagcaacgtacagcatcgtttgccttt	CRISPR spacer
aatgacagcaaagtacatcatcggcacagttg	Protospacer
*********** ***** ***** .    **

67. spacer 3.3|1356337|32|NC_014034|CRISPRCasFinder matches to NZ_CP039965 (Pseudorhodobacter sp. S12M18 plasmid unnamed1, complete sequence) position: , mismatch: 9, identity: 0.719

acccagaac---aggtgtttgagcggcccacccgc	CRISPR spacer
---tggggcgcaaggtgtttgaccgccccacccgc	Protospacer
   ..*..*   ********** ** *********

68. spacer 5.5|1395665|34|NC_014034|PILER-CR,CRISPRCasFinder,CRT matches to NC_014159 (Tsukamurella paurometabola DSM 20162 plasmid pTpau01, complete sequence) position: , mismatch: 9, identity: 0.735

atctgcatgtagtcggcgggcagttcgagccgca	CRISPR spacer
gcgcgcaggtagtcggcgggcagttcgatgcgtc	Protospacer
.. .*** ********************  **.

69. spacer 5.5|1395665|34|NC_014034|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP046100 (Rhodococcus sp. AQ5-07 plasmid unnamed1, complete sequence) position: , mismatch: 9, identity: 0.735

atctgcatgtagtcggcgggcagttcgagccgca	CRISPR spacer
agctgggtgtagtcggcgggcagttcggctggag	Protospacer
* *** .********************. . * .

70. spacer 5.13|1396199|36|NC_014034|PILER-CR,CRISPRCasFinder,CRT matches to NZ_AP015031 (Pseudomonas putida strain KF715 plasmid pKF715B, complete sequence) position: , mismatch: 9, identity: 0.75

ccggcga--aaaacggccatgcctccgggtgtctggct	CRISPR spacer
--gacggcttcgacggccatggcgccgggtgtctggct	Protospacer
  *.**.    .********* * **************

71. spacer 5.13|1396199|36|NC_014034|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP044084 (Pseudomonas luteola strain FDAARGOS_637 plasmid unnamed1, complete sequence) position: , mismatch: 9, identity: 0.75

ccggcga--aaaacggccatgcctccgggtgtctggct	CRISPR spacer
--gacggcttcgacggccatggcgccgggtgtctggct	Protospacer
  *.**.    .********* * **************

72. spacer 5.16|1396402|36|NC_014034|PILER-CR,CRISPRCasFinder,CRT matches to NZ_LR594677 (Variovorax sp. PBS-H4 plasmid 3) position: , mismatch: 9, identity: 0.75

cgcgccctgcgggtgatggcgacgggcaccacggcg	CRISPR spacer
caggccgcgcgggtgatggcgacgggcaccgtaaag	Protospacer
*. *** .**********************.... *

73. spacer 5.16|1396402|36|NC_014034|PILER-CR,CRISPRCasFinder,CRT matches to NZ_LR594661 (Variovorax sp. PBL-H6 plasmid 3) position: , mismatch: 9, identity: 0.75

cgcgccctgcgggtgatggcgacgggcaccacggcg	CRISPR spacer
caggccgcgcgggtgatggcgacgggcaccgtaaag	Protospacer
*. *** .**********************.... *

74. spacer 5.16|1396402|36|NC_014034|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP044974 (Hydrogenophaga sp. PBL-H3 substr. PBL-H3(B4) plasmid pPBL-H3_B4-2, complete sequence) position: , mismatch: 9, identity: 0.75

cgcgccctgcgggtgatggcgacgggcaccacggcg	CRISPR spacer
caggccgcgcgggtgatggcgacgggcaccgtaaag	Protospacer
*. *** .**********************.... *

75. spacer 5.16|1396402|36|NC_014034|PILER-CR,CRISPRCasFinder,CRT matches to AP018707 (Uncultured bacterium plasmid pSN1104-11 DNA, complete sequence) position: , mismatch: 9, identity: 0.75

cgcgccctgcgggtgatggcgacgggcaccacggcg	CRISPR spacer
caggccgcgcgggtgatggcgacgggcaccgtaaag	Protospacer
*. *** .**********************.... *

76. spacer 5.16|1396402|36|NC_014034|PILER-CR,CRISPRCasFinder,CRT matches to AP018708 (Uncultured bacterium plasmid pSN1104-34 DNA, complete sequence) position: , mismatch: 9, identity: 0.75

cgcgccctgcgggtgatggcgacgggcaccacggcg	CRISPR spacer
caggccgcgcgggtgatggcgacgggcaccgtaaag	Protospacer
*. *** .**********************.... *

77. spacer 5.16|1396402|36|NC_014034|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP044977 (Hydrogenophaga sp. PBL-H3 substr. PBL-H3(B2) plasmid pPBL-H3_B2-2, complete sequence) position: , mismatch: 9, identity: 0.75

cgcgccctgcgggtgatggcgacgggcaccacggcg	CRISPR spacer
caggccgcgcgggtgatggcgacgggcaccgtaaag	Protospacer
*. *** .**********************.... *

78. spacer 5.16|1396402|36|NC_014034|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP044551 (Hydrogenophaga sp. BPS33 plasmid pBPS33-2, complete sequence) position: , mismatch: 9, identity: 0.75

cgcgccctgcgggtgatggcgacgggcaccacggcg	CRISPR spacer
caggccgcgcgggtgatggcgacgggcaccgtaaag	Protospacer
*. *** .**********************.... *

79. spacer 5.19|1396605|34|NC_014034|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP036297 (Planctomycetes bacterium Pla86 plasmid pPla86_1, complete sequence) position: , mismatch: 9, identity: 0.735

gatttcgtcgcttacgacgcctatctgatttcgg	CRISPR spacer
tgattcgtcgcttacgccgcctagctgccgccgg	Protospacer
 . ************* ****** *** . .***

80. spacer 5.19|1396605|34|NC_014034|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP036288 (Planctomycetes bacterium Pla133 plasmid pPla133_1, complete sequence) position: , mismatch: 9, identity: 0.735

gatttcgtcgcttacgacgcctatctgatttcgg	CRISPR spacer
tgattcgtcgcttacgccgcctagctgccgccgg	Protospacer
 . ************* ****** *** . .***

81. spacer 5.24|1396935|34|NC_014034|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP026091 (Ralstonia solanacearum strain IBSBF 2570 plasmid unnamed, complete sequence) position: , mismatch: 9, identity: 0.735

agcctgcgcggccgcatcggcttccgcctgcgtg	CRISPR spacer
cgcgcggatcgccgcgtcgacttccgcctgcgtg	Protospacer
 ** .* .. *****.***.**************

82. spacer 5.24|1396935|34|NC_014034|PILER-CR,CRISPRCasFinder,CRT matches to NC_014309 (Ralstonia solanacearum CFBP2957 plasmid RCFBPv3_mp, complete genome) position: , mismatch: 9, identity: 0.735

agcctgcgcggccgcatcggcttccgcctgcgtg	CRISPR spacer
cgcgcggatcgccgcgtcgacttccgcctgcgtg	Protospacer
 ** .* .. *****.***.**************

83. spacer 5.24|1396935|34|NC_014034|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP026093 (Ralstonia solanacearum strain SFC plasmid unnamed, complete sequence) position: , mismatch: 9, identity: 0.735

agcctgcgcggccgcatcggcttccgcctgcgtg	CRISPR spacer
cgcgcggatcgccgcgtcgacttccgcctgcgtg	Protospacer
 ** .* .. *****.***.**************

84. spacer 5.24|1396935|34|NC_014034|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP021767 (Ralstonia solanacearum strain RS 489 plasmid unnamed, complete sequence) position: , mismatch: 9, identity: 0.735

agcctgcgcggccgcatcggcttccgcctgcgtg	CRISPR spacer
cgcgcggatcgccgcgtcgacttccgcctgcgtg	Protospacer
 ** .* .. *****.***.**************

85. spacer 5.24|1396935|34|NC_014034|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP021653 (Ralstonia solanacearum strain RS 488 plasmid unnamed, complete sequence) position: , mismatch: 9, identity: 0.735

agcctgcgcggccgcatcggcttccgcctgcgtg	CRISPR spacer
cgcgcggatcgccgcgtcgacttccgcctgcgtg	Protospacer
 ** .* .. *****.***.**************

86. spacer 5.24|1396935|34|NC_014034|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP012688 (Ralstonia solanacearum strain UY031 plasmid unnamed, complete sequence) position: , mismatch: 9, identity: 0.735

agcctgcgcggccgcatcggcttccgcctgcgtg	CRISPR spacer
cgcgcggatcgccgcgtcgacttccgcctgcgtg	Protospacer
 ** .* .. *****.***.**************

87. spacer 5.24|1396935|34|NC_014034|PILER-CR,CRISPRCasFinder,CRT matches to CP047139 (Ralstonia solanacearum strain CFBP 8695 plasmid unnamed, complete sequence) position: , mismatch: 9, identity: 0.735

agcctgcgcggccgcatcggcttccgcctgcgtg	CRISPR spacer
cgcgcggatcgccgcgtcgacttccgcctgcgtg	Protospacer
 ** .* .. *****.***.**************

88. spacer 5.24|1396935|34|NC_014034|PILER-CR,CRISPRCasFinder,CRT matches to CP047137 (Ralstonia solanacearum strain CFBP 8697 plasmid unnamed, complete sequence) position: , mismatch: 9, identity: 0.735

agcctgcgcggccgcatcggcttccgcctgcgtg	CRISPR spacer
cgcgcggatcgccgcgtcgacttccgcctgcgtg	Protospacer
 ** .* .. *****.***.**************

89. spacer 5.25|1397001|33|NC_014034|PILER-CR,CRISPRCasFinder,CRT matches to NC_003903 (Streptomyces coelicolor A3(2) plasmid SCP1, complete sequence) position: , mismatch: 9, identity: 0.727

atcagctcgtcgttggtcagccggacgatgtcc	CRISPR spacer
ttgcggatctcgttcgtcagccggacgacgtcc	Protospacer
 *  *  . ***** *************.****

90. spacer 5.25|1397001|33|NC_014034|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP046573 (Rhodococcus sp. WAY2 plasmid pRWAY01, complete sequence) position: , mismatch: 9, identity: 0.727

atcagctcgtcgttggtcagccggacgatgtcc	CRISPR spacer
gcgaagtactcgttggtcagccggaagttgtcc	Protospacer
.. *. *  **************** * *****

91. spacer 5.28|1397199|35|NC_014034|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP018096 (Chelatococcus daeguensis strain TAD1 plasmid pTAD1, complete sequence) position: , mismatch: 9, identity: 0.743

gtgtctgccacgacgccctgcaccagatccgcgcc	CRISPR spacer
tcgcggccttcgacgccctgcagcagatccgcgcc	Protospacer
 .*.   *. ************ ************

92. spacer 5.33|1397532|35|NC_014034|PILER-CR,CRISPRCasFinder,CRT matches to NC_006362 (Nocardia farcinica IFM 10152 plasmid pNF1, complete sequence) position: , mismatch: 9, identity: 0.743

aacccgatcatggcccgcctcagcgccgcgctgac	CRISPR spacer
gcgccgatcatggccggcctcatcgccgcagtcat	Protospacer
.  ************ ****** ******. * *.

93. spacer 2.2|1349659|35|NC_014034|PILER-CR matches to NZ_CP011665 (Streptomyces sp. Mg1 plasmid pSMg1-1, complete sequence) position: , mismatch: 10, identity: 0.714

acgggggcggcggcgaggcaggcgaaggcggcggc	CRISPR spacer
gtgatggcgacggcgaggcaggcgagggcgaggag	Protospacer
..*. ****.***************.****. *.

94. spacer 5.5|1395665|34|NC_014034|PILER-CR,CRISPRCasFinder,CRT matches to NZ_LN832562 (Paracoccus aminovorans isolate JCM7685 plasmid IV, complete sequence) position: , mismatch: 10, identity: 0.706

atctgcatgtagtcggcgggcagttcgagccgca	CRISPR spacer
gtgcgggccgagacggcgggcagttcgggccgca	Protospacer
.* .* ..  ** **************.******

95. spacer 5.22|1396803|33|NC_014034|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP026653 (Streptomyces dengpaensis strain XZHG99 plasmid unnamed1, complete sequence) position: , mismatch: 10, identity: 0.697

cgtgtggatgatcatgcagcgcggacggcttgg	CRISPR spacer
tagccgcgtgatcatgcagcgtggacgggttgc	Protospacer
..  .* .*************.****** ***

96. spacer 5.24|1396935|34|NC_014034|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP022775 (Ralstonia solanacearum strain T12 plasmid unnamed, complete sequence) position: , mismatch: 10, identity: 0.706

agcctgcgcggccgcatcggcttccgcctgcgtg	CRISPR spacer
cgagcggatcgccgcgtcgacttccgcctgcgtg	Protospacer
 *  .* .. *****.***.**************

97. spacer 5.24|1396935|34|NC_014034|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP022762 (Ralstonia solanacearum strain T95 plasmid unnamed, complete sequence) position: , mismatch: 10, identity: 0.706

agcctgcgcggccgcatcggcttccgcctgcgtg	CRISPR spacer
cgagcggatcgccgcgtcgacttccgcctgcgtg	Protospacer
 *  .* .. *****.***.**************

98. spacer 5.24|1396935|34|NC_014034|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP037902 (Cupriavidus metallidurans strain BS1 plasmid p1, complete sequence) position: , mismatch: 10, identity: 0.706

agcctgcgcggccgcatcggcttccgcctgcgtg	CRISPR spacer
agcgtgcgcggccggatcggcttcgatgtcggcc	Protospacer
*** ********** ********* .. *  *.

99. spacer 5.24|1396935|34|NC_014034|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP007129 (Gemmatirosa kalamazoonesis strain KBS708 plasmid 1, complete sequence) position: , mismatch: 10, identity: 0.706

agcctgcgcggccgcatcggcttccgcctgcgtg	CRISPR spacer
gcgctgcgcggccgctacggcttccgcggcctcg	Protospacer
.  ************  **********   * .*

100. spacer 5.24|1396935|34|NC_014034|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP046332 (Cupriavidus metallidurans strain FDAARGOS_675 plasmid unnamed2) position: , mismatch: 10, identity: 0.706

agcctgcgcggccgcatcggcttccgcctgcgtg	CRISPR spacer
agcgtgcgcggccggatcggcttcgatgtcggcc	Protospacer
*** ********** ********* .. *  *.

101. spacer 5.24|1396935|34|NC_014034|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP026546 (Cupriavidus metallidurans strain Ni-2 plasmid unnamed2) position: , mismatch: 10, identity: 0.706

agcctgcgcggccgcatcggcttccgcctgcgtg	CRISPR spacer
agcgtgcgcggccggatcggcttcgatgtcggcc	Protospacer
*** ********** ********* .. *  *.

102. spacer 5.24|1396935|34|NC_014034|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP023017 (Ralstonia solanacearum strain SL3022 plasmid unnamed, complete sequence) position: , mismatch: 10, identity: 0.706

agcctgcgcggccgcatcggcttccgcctgcgtg	CRISPR spacer
cgagcggatcgccgcgtcgacttccgcctgcgtg	Protospacer
 *  .* .. *****.***.**************

103. spacer 5.24|1396935|34|NC_014034|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP014703 (Ralstonia solanacearum strain KACC 10722 plasmid, complete sequence) position: , mismatch: 10, identity: 0.706

agcctgcgcggccgcatcggcttccgcctgcgtg	CRISPR spacer
cgagcggatcgccgcgtcgacttccgcctgcgtg	Protospacer
 *  .* .. *****.***.**************

104. spacer 5.24|1396935|34|NC_014034|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP022771 (Ralstonia solanacearum strain T51 plasmid unnamed, complete sequence) position: , mismatch: 10, identity: 0.706

agcctgcgcggccgcatcggcttccgcctgcgtg	CRISPR spacer
cgagcggatcgccgcgtcgacttccgcctgcgtg	Protospacer
 *  .* .. *****.***.**************

105. spacer 5.24|1396935|34|NC_014034|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP022777 (Ralstonia solanacearum strain T11 plasmid unnamed, complete sequence) position: , mismatch: 10, identity: 0.706

agcctgcgcggccgcatcggcttccgcctgcgtg	CRISPR spacer
cgagcggatcgccgcgtcgacttccgcctgcgtg	Protospacer
 *  .* .. *****.***.**************

106. spacer 5.24|1396935|34|NC_014034|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP022799 (Ralstonia solanacearum strain SL2064 plasmid unnamed, complete sequence) position: , mismatch: 10, identity: 0.706

agcctgcgcggccgcatcggcttccgcctgcgtg	CRISPR spacer
cgagcggatcgccgcgtcgacttccgcctgcgtg	Protospacer
 *  .* .. *****.***.**************

107. spacer 5.24|1396935|34|NC_014034|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP022764 (Ralstonia solanacearum strain T82 plasmid unnamed, complete sequence) position: , mismatch: 10, identity: 0.706

agcctgcgcggccgcatcggcttccgcctgcgtg	CRISPR spacer
cgagcggatcgccgcgtcgacttccgcctgcgtg	Protospacer
 *  .* .. *****.***.**************

108. spacer 5.24|1396935|34|NC_014034|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP022797 (Ralstonia solanacearum strain SL2312 plasmid unnamed, complete sequence) position: , mismatch: 10, identity: 0.706

agcctgcgcggccgcatcggcttccgcctgcgtg	CRISPR spacer
cgagcggatcgccgcgtcgacttccgcctgcgtg	Protospacer
 *  .* .. *****.***.**************

109. spacer 5.24|1396935|34|NC_014034|PILER-CR,CRISPRCasFinder,CRT matches to NC_006466 (Cupriavidus metallidurans CH34 plasmid pMOL30, complete sequence) position: , mismatch: 10, identity: 0.706

agcctgcgcggccgcatcggcttccgcctgcgtg	CRISPR spacer
agcgtgcgcggccggatcggcttcgatgtcggcc	Protospacer
*** ********** ********* .. *  *.

110. spacer 5.24|1396935|34|NC_014034|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP043439 (Cupriavidus campinensis strain MJ1 plasmid unnamed2, complete sequence) position: , mismatch: 10, identity: 0.706

agcctgcgcggccgcatcggcttccgcctgcgtg	CRISPR spacer
agcgtgcgcggccggatcggcttcgatgtcggcc	Protospacer
*** ********** ********* .. *  *.

111. spacer 5.24|1396935|34|NC_014034|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP022758 (Ralstonia solanacearum strain T101 plasmid unnamed, complete sequence) position: , mismatch: 10, identity: 0.706

agcctgcgcggccgcatcggcttccgcctgcgtg	CRISPR spacer
cgagcggatcgccgcgtcgacttccgcctgcgtg	Protospacer
 *  .* .. *****.***.**************

112. spacer 5.33|1397532|35|NC_014034|PILER-CR,CRISPRCasFinder,CRT matches to NC_022049 (Paracoccus aminophilus JCM 7686 plasmid pAMI4, complete sequence) position: , mismatch: 10, identity: 0.714

aacccgatcatggcccgcctcagcgccgcgctgac	CRISPR spacer
ggcgcgaacaaggcccgcctcagcgccgccgaaag	Protospacer
..* *** ** ******************   .*

113. spacer 5.34|1397599|34|NC_014034|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP012748 (Paraburkholderia caribensis MBA4 plasmid unnamed, complete sequence) position: , mismatch: 10, identity: 0.706

atccgcggatcggcgtgacccgccccgcccatcg	CRISPR spacer
atccgcagatcggcgtgatccgccgcttctggtc	Protospacer
******.***********.***** * .*.. .

114. spacer 5.24|1396935|34|NC_014034|PILER-CR,CRISPRCasFinder,CRT matches to NZ_CP039912 (Agrobacterium tumefaciens strain CFBP6625 plasmid pAtCFBP6625a, complete sequence) position: , mismatch: 11, identity: 0.676

agcctgcgcggccgcatcggcttccgcctgcgtg	CRISPR spacer
gctctgcgcggcttcatcggcttccgcggcaacg	Protospacer
. .*********. *************    ..*

115. spacer 5.25|1397001|33|NC_014034|PILER-CR,CRISPRCasFinder,CRT matches to CP054928 (Streptomyces fulvissimus strain NA06532 plasmid unnamed2, complete sequence) position: , mismatch: 11, identity: 0.667

atcagctcgtcgttggtcagccggacgatgtcc	CRISPR spacer
ggggagtcgtcgtcggtcagccggaagatggtg	Protospacer
.  .. *******.*********** **** .

116. spacer 5.19|1396605|34|NC_014034|PILER-CR,CRISPRCasFinder,CRT matches to MG592644 (Vibrio phage 1.276.O._10N.286.54.E4, partial genome) position: , mismatch: 12, identity: 0.647

gatttcgtcgcttacgacgcctatctgatttcgg	CRISPR spacer
acaagtacagctcacaacgcctatctgatttcgt	Protospacer
.    ... ***.**.*****************

117. spacer 5.19|1396605|34|NC_014034|PILER-CR,CRISPRCasFinder,CRT matches to MG592567 (Vibrio phage 1.198.A._10N.286.54.F4, partial genome) position: , mismatch: 12, identity: 0.647

gatttcgtcgcttacgacgcctatctgatttcgg	CRISPR spacer
acaagtacagctcacaacgcctatctgatttcgt	Protospacer
.    ... ***.**.*****************

118. spacer 5.19|1396605|34|NC_014034|PILER-CR,CRISPRCasFinder,CRT matches to MG592568 (Vibrio phage 1.198.B._10N.286.54.F4, partial genome) position: , mismatch: 12, identity: 0.647

gatttcgtcgcttacgacgcctatctgatttcgg	CRISPR spacer
acaagtacagctcacaacgcctatctgatttcgt	Protospacer
.    ... ***.**.*****************

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

980420 : 1093535

118

Rhodobacter_phage(69.74%)

head,holin,transposase,capsid,portal,integrase,tail,protease,terminase

attL 1038025:1038044|attR 1070594:1070613

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_023911097.1\|980420_981467_-\|holin	choline ABC transporter ATP-binding protein	G3M9Y6	Bacillus_virus	2.1e-19	33.2
WP_013066638.1\|981478_982495_-\|holin	choline ABC transporter permease subunit	NA	NA	NA	NA
WP_013066639.1\|982585_983512_-\|holin	choline ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_013066640.1\|983628_984213_+	transcriptional regulator BetI	NA	NA	NA	NA
WP_013066641.1\|984209_985661_+	betaine-aldehyde dehydrogenase	NA	NA	NA	NA
WP_013066642.1\|985744_987400_+\|holin	choline dehydrogenase	A0A1V0S9M4	Catovirus	6.5e-55	30.0
WP_013066643.1\|987453_988089_+	thermonuclease family protein	NA	NA	NA	NA
WP_013066644.1\|988163_988718_+	DUF1003 domain-containing protein	NA	NA	NA	NA
WP_013066645.1\|988793_989033_+	DUF465 domain-containing protein	NA	NA	NA	NA
WP_013066646.1\|989092_990490_-	XRE family transcriptional regulator	NA	NA	NA	NA
WP_013066647.1\|990599_991160_+	hypothetical protein	NA	NA	NA	NA
WP_013066648.1\|991153_992338_-	multidrug effflux MFS transporter	NA	NA	NA	NA
WP_013066649.1\|992623_992974_-	DMT family protein	NA	NA	NA	NA
WP_013066650.1\|993150_994683_+	acyl-CoA carboxylase subunit beta	NA	NA	NA	NA
WP_013066651.1\|994693_995233_+	hypothetical protein	NA	NA	NA	NA
WP_013066653.1\|995660_996059_+	hypothetical protein	NA	NA	NA	NA
WP_013066654.1\|996387_996597_+	hypothetical protein	NA	NA	NA	NA
WP_013066655.1\|996750_998736_+	acetyl/propionyl/methylcrotonyl-CoA carboxylase subunit alpha	NA	NA	NA	NA
WP_013066656.1\|998826_1000956_+	methylmalonyl-CoA mutase	NA	NA	NA	NA
WP_013066657.1\|1001078_1001564_-	bacterioferritin	NA	NA	NA	NA
WP_013066658.1\|1001585_1001828_-	(2Fe-2S)-binding protein	NA	NA	NA	NA
WP_080514577.1\|1001826_1002693_+	phosphatidylserine decarboxylase	A0A1V0SDU9	Indivirus	1.4e-11	38.8
WP_013066660.1\|1002694_1003432_+	CDP-diacylglycerol--serine O-phosphatidyltransferase	NA	NA	NA	NA
WP_131618281.1\|1009753_1010872_+	hypothetical protein	NA	NA	NA	NA
WP_013066661.1\|1011160_1011400_-	hypothetical protein	NA	NA	NA	NA
WP_013066662.1\|1011423_1012062_-	N-acetylmuramoyl-L-alanine amidase	F8TVB6	EBPR_siphovirus	2.9e-59	56.0
WP_013066663.1\|1012293_1014177_-	DUF2793 domain-containing protein	A0A0K1LM54	Rhodobacter_phage	2.2e-30	31.0
WP_013066664.1\|1014190_1018162_-\|tail	glycoside hydrolase/phage tail family protein	A0A0B5A7K5	Paracoccus_phage	6.9e-252	39.9
WP_013066665.1\|1018167_1018623_-	peptidase	F4YXU4	Roseobacter_phage	6.0e-27	43.7
WP_013066666.1\|1018615_1019521_-	DUF2163 domain-containing protein	A0A1V0DY93	Dinoroseobacter_phage	3.3e-61	43.8
WP_013066667.1\|1019517_1019817_-	hypothetical protein	NA	NA	NA	NA
WP_013066668.1\|1019813_1020440_-	DUF2460 domain-containing protein	A0A0B5A2K3	Paracoccus_phage	1.0e-61	56.8
WP_013066669.1\|1020440_1022537_-\|tail	phage tail length tape measure family protein	A0A0B5A0F2	Paracoccus_phage	6.2e-18	29.1
WP_181443899.1\|1022533_1022677_-	hypothetical protein	NA	NA	NA	NA
WP_013066671.1\|1022805_1023213_-	hypothetical protein	NA	NA	NA	NA
WP_013066672.1\|1023224_1024169_-	hypothetical protein	G8DH51	Emiliania_huxleyi_virus	7.7e-85	51.1
WP_013066673.1\|1024193_1024634_-	hypothetical protein	G8DH50	Emiliania_huxleyi_virus	2.4e-28	50.4
WP_013066674.1\|1024687_1025884_-	DUF4935 domain-containing protein	NA	NA	NA	NA
WP_013066675.1\|1026001_1026643_-	hypothetical protein	NA	NA	NA	NA
WP_013066676.1\|1026639_1026954_-	hypothetical protein	NA	NA	NA	NA
WP_013066677.1\|1026955_1027294_-	DUF2190 family protein	A0A2I7QRW1	Vibrio_phage	7.4e-06	37.6
WP_013066678.1\|1027320_1029339_-\|head,protease	HK97 family phage prohead protease	A0A2I7QRU0	Vibrio_phage	7.4e-69	30.4
WP_013066679.1\|1029431_1029989_+	hypothetical protein	NA	NA	NA	NA
WP_013066680.1\|1029997_1031521_-\|portal	phage portal protein	B7SYD6	Stenotrophomonas_phage	4.0e-83	39.3
WP_013066681.1\|1031517_1031727_-	hypothetical protein	NA	NA	NA	NA
WP_050759960.1\|1031726_1033652_-\|terminase	phage terminase large subunit family protein	A0A2H4JIC6	uncultured_Caudovirales_phage	7.3e-199	56.4
WP_013066683.1\|1033695_1034304_-	hypothetical protein	A0A2H4JCL4	uncultured_Caudovirales_phage	4.4e-33	47.5
WP_013066684.1\|1034395_1034617_+	hypothetical protein	NA	NA	NA	NA
WP_013066685.1\|1034628_1035546_+	hypothetical protein	NA	NA	NA	NA
WP_131618282.1\|1035579_1035882_-	hypothetical protein	NA	NA	NA	NA
WP_013066686.1\|1035950_1036655_-	pyridoxal-phosphate dependent enzyme	NA	NA	NA	NA
WP_013066687.1\|1036651_1037626_-	DNA methyltransferase	A0A1P8VV91	Erythrobacter_phage	9.8e-59	31.5
WP_013066688.1\|1037618_1038395_-	ParB N-terminal domain-containing protein	K4HZA5	Acidithiobacillus_phage	2.3e-47	69.4
1038025:1038044	attL	NA	NA	NA	NA
WP_013066689.1\|1038655_1039177_-	hypothetical protein	NA	NA	NA	NA
WP_013066690.1\|1039206_1040172_-	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_131618283.1\|1040168_1040363_-	hypothetical protein	NA	NA	NA	NA
WP_013066692.1\|1040376_1040631_-	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_013066693.1\|1040945_1041536_+	hypothetical protein	NA	NA	NA	NA
WP_013066694.1\|1041678_1042908_+\|integrase	tyrosine-type recombinase/integrase	A0A221SAN4	Ralstonia_phage	4.6e-37	33.1
WP_031320977.1\|1043105_1046486_+	type I restriction-modification system endonuclease	A0A2P1MXB6	Escherichia_phage	6.7e-06	22.8
WP_013066696.1\|1046485_1047955_+	N-6 DNA methylase	A0A2H4UVB0	Bodo_saltans_virus	4.1e-16	27.6
WP_013066697.1\|1047951_1048878_+	GIY-YIG nuclease family protein	NA	NA	NA	NA
WP_013066698.1\|1048874_1050500_+	restriction endonuclease subunit S	B3GAM1	uncultured_virus	1.5e-11	23.8
WP_013066699.1\|1050499_1052152_+	AAA family ATPase	NA	NA	NA	NA
WP_013066700.1\|1052148_1053003_+	hypothetical protein	NA	NA	NA	NA
WP_013066702.1\|1053809_1054994_+\|transposase	IS110 family transposase	A0A0U3ULR1	Bacillus_phage	1.3e-20	26.0
WP_013066703.1\|1055081_1056062_-	hypothetical protein	G8GWG3	Rhodobacter_phage	7.0e-174	100.0
WP_013066704.1\|1056061_1056328_-	hypothetical protein	G8GWG2	Rhodobacter_phage	8.6e-34	100.0
WP_013066705.1\|1056358_1057690_-	hypothetical protein	G8GWG1	Rhodobacter_phage	5.0e-255	100.0
WP_013066706.1\|1057716_1061145_-\|tail	tail protein	G8GWG0	Rhodobacter_phage	0.0e+00	100.0
WP_013066707.1\|1061141_1061582_-	C40 family peptidase	G8GWF9	Rhodobacter_phage	3.0e-84	100.0
WP_013066708.1\|1061584_1062112_-	hypothetical protein	G8GWF8	Rhodobacter_phage	2.8e-92	100.0
WP_013066709.1\|1062108_1062531_-	hypothetical protein	G8GWF7	Rhodobacter_phage	3.7e-63	100.0
WP_013066710.1\|1062527_1065611_-\|tail	phage tail length tape measure family protein	G8GWF6	Rhodobacter_phage	0.0e+00	100.0
WP_013066711.1\|1065612_1065828_-	DUF1799 domain-containing protein	G8GWF5	Rhodobacter_phage	4.8e-35	98.6
WP_013066712.1\|1065961_1066339_-	hypothetical protein	G8GWF4	Rhodobacter_phage	8.9e-69	100.0
WP_013066713.1\|1066471_1067398_-	hypothetical protein	G8GWF3	Rhodobacter_phage	2.0e-170	100.0
WP_013066714.1\|1067400_1067598_-	hypothetical protein	G8GWF2	Rhodobacter_phage	8.9e-28	100.0
WP_013066715.1\|1067600_1068032_-	hypothetical protein	G8GWF1	Rhodobacter_phage	1.0e-76	100.0
WP_013066716.1\|1068031_1068457_-	DUF1320 domain-containing protein	G8GWF0	Rhodobacter_phage	4.4e-72	100.0
WP_013066717.1\|1068456_1068747_-	hypothetical protein	G8GWE9	Rhodobacter_phage	3.0e-48	100.0
WP_013066718.1\|1068817_1069306_-	hypothetical protein	G8GWE8	Rhodobacter_phage	4.0e-53	100.0
WP_013066719.1\|1069370_1070324_-\|capsid	major capsid protein	G8GWE7	Rhodobacter_phage	2.6e-181	100.0
WP_013066720.1\|1070334_1070679_-	DUF2190 family protein	G8GWE6	Rhodobacter_phage	5.3e-52	100.0
1070594:1070613	attR	NA	NA	NA	NA
WP_013066721.1\|1070691_1071804_-	hypothetical protein	G8GWE4	Rhodobacter_phage	8.8e-189	100.0
WP_013066722.1\|1072071_1072626_-	phage virion morphogenesis protein	G8GWE3	Rhodobacter_phage	4.6e-98	100.0
WP_013066723.1\|1072718_1074200_-\|head	head morphogenesis protein	G8GWE2	Rhodobacter_phage	4.9e-296	100.0
WP_013066724.1\|1074295_1075672_-	DUF935 family protein	G8GWE1	Rhodobacter_phage	2.8e-261	99.8
WP_013066725.1\|1075668_1075893_-	hypothetical protein	G8GWE0	Rhodobacter_phage	2.6e-39	100.0
WP_016042342.1\|1075889_1076228_-	hypothetical protein	G8GWD9	Rhodobacter_phage	2.7e-64	100.0
WP_016042341.1\|1076227_1076377_-	hypothetical protein	G8GWD8	Rhodobacter_phage	2.3e-20	100.0
WP_013066727.1\|1076376_1078035_-\|terminase	phage terminase large subunit	G8GWD7	Rhodobacter_phage	3.0e-312	99.8
WP_013066728.1\|1078031_1078535_-	DUF1804 family protein	G8GWD6	Rhodobacter_phage	1.2e-84	100.0
WP_013066729.1\|1078521_1078788_-	hemolysin XhlA family protein	G8GWD5	Rhodobacter_phage	2.5e-41	100.0
WP_013066730.1\|1078784_1079297_-	hypothetical protein	G8GWD4	Rhodobacter_phage	2.2e-86	100.0
WP_013066731.1\|1079296_1080226_-	lysozyme	G8GWD3	Rhodobacter_phage	3.7e-172	100.0
WP_013066732.1\|1080297_1080666_-	helix-turn-helix domain-containing protein	G8GWD2	Rhodobacter_phage	1.1e-63	100.0
WP_013066733.1\|1080714_1081392_-	DUF2786 domain-containing protein	G8GWD1	Rhodobacter_phage	9.9e-119	100.0
WP_013066735.1\|1081495_1081942_-	regulatory protein GemA	G8GWC9	Rhodobacter_phage	6.0e-80	100.0
WP_013066736.1\|1081938_1082154_-	hypothetical protein	G8GWC8	Rhodobacter_phage	1.1e-34	100.0
WP_013066737.1\|1082150_1083035_-	hypothetical protein	G8GWC7	Rhodobacter_phage	3.7e-158	100.0
WP_013066738.1\|1083111_1083387_-	HU family DNA-binding protein	G8GWC6	Rhodobacter_phage	2.3e-42	100.0
WP_016042339.1\|1083479_1083713_-	hypothetical protein	G8GWC5	Rhodobacter_phage	3.3e-37	100.0
WP_013066740.1\|1083712_1084255_-	host-nuclease inhibitor Gam family protein	G8GWC4	Rhodobacter_phage	3.8e-89	100.0
WP_013066741.1\|1084241_1084607_-	hypothetical protein	G8GWC3	Rhodobacter_phage	2.6e-65	100.0
WP_013066742.1\|1084597_1085185_-	hypothetical protein	G8GWC2	Rhodobacter_phage	1.1e-100	100.0
WP_013066743.1\|1085184_1085958_-	ATP-binding protein	G8GWC1	Rhodobacter_phage	3.9e-143	100.0
WP_044033673.1\|1085990_1088279_-\|transposase	Mu transposase C-terminal domain-containing protein	G8GWC0	Rhodobacter_phage	0.0e+00	99.9
WP_013066745.1\|1088287_1088755_-	hypothetical protein	G8GWB9	Rhodobacter_phage	3.3e-81	100.0
WP_013066746.1\|1088756_1089608_-	ParB N-terminal domain-containing protein	G8GWB8	Rhodobacter_phage	1.8e-154	100.0
WP_013066747.1\|1089617_1089809_-	hypothetical protein	G8GWB7	Rhodobacter_phage	4.4e-24	100.0
WP_013066748.1\|1089808_1090099_-	hypothetical protein	G8GWB6	Rhodobacter_phage	7.6e-52	100.0
WP_013066751.1\|1090344_1090662_-	hypothetical protein	G8GWB3	Rhodobacter_phage	2.7e-50	100.0
WP_013066752.1\|1090658_1090952_-	helix-turn-helix domain-containing protein	G8GWB2	Rhodobacter_phage	4.0e-48	100.0
WP_016042336.1\|1091096_1091813_+	helix-turn-helix domain-containing protein	G8GWB1	Rhodobacter_phage	5.0e-137	100.0
WP_013066754.1\|1091974_1092355_+	hypothetical protein	G8GWB0	Rhodobacter_phage	8.4e-67	100.0
WP_013066755.1\|1092366_1092843_+	hypothetical protein	G8GWA9	Rhodobacter_phage	2.4e-87	100.0
WP_013066756.1\|1092845_1093535_+	hypothetical protein	G8GWA8	Rhodobacter_phage	2.0e-135	100.0

DBSCAN-SWA_2

1519773 : 1527630

Emiliania_huxleyi_virus(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_013067131.1\|1519773_1520343_-	lysozyme	F8TV87	EBPR_siphovirus	3.1e-41	51.4
WP_013067133.1\|1520471_1520822_-	hypothetical protein	NA	NA	NA	NA
WP_013067134.1\|1520818_1521445_-	DUF2460 domain-containing protein	A0A0B5A2K3	Paracoccus_phage	3.5e-62	55.8
WP_013067135.1\|1521454_1523896_-	hypothetical protein	A0A0K1LLC2	Rhodobacter_phage	3.3e-15	42.9
WP_031321105.1\|1523888_1524080_-	hypothetical protein	G8DH53	Emiliania_huxleyi_virus	4.2e-06	61.9
WP_013067137.1\|1524557_1525454_-	hypothetical protein	G8DH51	Emiliania_huxleyi_virus	1.2e-87	54.5
WP_013067138.1\|1525478_1525901_-	hypothetical protein	G8DH50	Emiliania_huxleyi_virus	1.1e-35	52.9
WP_013067139.1\|1526031_1526985_+	serine/threonine protein kinase	W5S4J6	Pithovirus	7.9e-13	26.4
WP_013067140.1\|1527006_1527630_-	hypothetical protein	G8DH49	Emiliania_huxleyi_virus	1.4e-50	50.7

DBSCAN-SWA_3

1762772 : 1835558

Roseobacter_phage(18.75%)

head,capsid,portal,tRNA,tail,protease

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_050759972.1\|1762772_1764083_+\|protease	RIP metalloprotease RseP	NA	NA	NA	NA
WP_013067355.1\|1764176_1764350_+	hypothetical protein	NA	NA	NA	NA
WP_013067356.1\|1764471_1766874_+	outer membrane protein assembly factor BamA	NA	NA	NA	NA
WP_013067357.1\|1766934_1767510_+	OmpH family outer membrane protein	NA	NA	NA	NA
WP_013067358.1\|1767614_1768076_+	3-hydroxyacyl-ACP dehydratase FabZ	NA	NA	NA	NA
WP_013067359.1\|1768078_1768873_+	acyl-ACP--UDP-N-acetylglucosamine O-acyltransferase	NA	NA	NA	NA
WP_080514600.1\|1768946_1769672_+	UDP-2,3-diacylglucosamine diphosphatase LpxI	NA	NA	NA	NA
WP_013067361.1\|1769668_1770820_+	lipid-A-disaccharide synthase	NA	NA	NA	NA
WP_013067362.1\|1770807_1771545_-	5-oxoprolinase subunit PxpA	NA	NA	NA	NA
WP_013067363.1\|1771541_1772555_-	biotin-dependent carboxyltransferase family protein	NA	NA	NA	NA
WP_013067364.1\|1772551_1773271_-	carboxyltransferase domain-containing protein	NA	NA	NA	NA
WP_013067365.1\|1773267_1774152_-	transglutaminase family protein	NA	NA	NA	NA
WP_013067366.1\|1774155_1776579_-	circularly permuted type 2 ATP-grasp protein	NA	NA	NA	NA
WP_013067367.1\|1776599_1780028_-	transglutaminase family protein	NA	NA	NA	NA
WP_013067368.1\|1780203_1783095_+	FAD:protein FMN transferase	NA	NA	NA	NA
WP_037091514.1\|1783091_1783964_-	transporter substrate-binding domain-containing protein	NA	NA	NA	NA
WP_013067370.1\|1783993_1784677_-	cytochrome c-550 PedF	NA	NA	NA	NA
WP_013067371.1\|1784877_1785858_+	ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_013067372.1\|1785866_1786685_+	ABC transporter permease subunit	NA	NA	NA	NA
WP_013067373.1\|1786681_1787275_+	ABC transporter ATP-binding protein	NA	NA	NA	NA
WP_013067374.1\|1787501_1788293_-	ABC transporter permease	NA	NA	NA	NA
WP_115503947.1\|1788289_1789090_-	ATP-binding cassette domain-containing protein	A0A2H4PQG7	Staphylococcus_phage	8.1e-11	26.3
WP_013067376.1\|1789028_1789454_-	hypothetical protein	NA	NA	NA	NA
WP_013067377.1\|1789462_1790425_-	YVTN family beta-propeller repeat protein	NA	NA	NA	NA
WP_013067378.1\|1790421_1791591_-	ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_013067379.1\|1791708_1792251_+	sel1 repeat family protein	NA	NA	NA	NA
WP_013067380.1\|1792364_1792751_+	c-type cytochrome	NA	NA	NA	NA
WP_013067381.1\|1793108_1794878_+	PQQ-dependent methanol/ethanol family dehydrogenase	A0A0B5IX34	Pandoravirus	2.2e-16	23.4
WP_013067382.1\|1795034_1795754_+	response regulator transcription factor	NA	NA	NA	NA
WP_013067383.1\|1795800_1796970_+	FIST C-terminal domain-containing protein	NA	NA	NA	NA
WP_013067384.1\|1796976_1799214_+	PAS-domain containing protein	A0A2K9L0Z8	Tupanvirus	1.7e-10	28.6
WP_044033654.1\|1799203_1800340_-\|tRNA	tRNA 2-thiouridine(34) synthase MnmA	NA	NA	NA	NA
WP_013067386.1\|1800466_1800745_+	DUF1153 domain-containing protein	NA	NA	NA	NA
WP_013067387.1\|1800840_1801554_+	response regulator transcription factor	F4YXP8	Roseobacter_phage	1.4e-17	49.5
WP_044033685.1\|1801620_1803741_+	NAD-dependent DNA ligase LigA	A0A289ZTZ3	Serratia_phage	9.8e-96	40.4
WP_013067389.1\|1803737_1805831_+	ATP-dependent DNA helicase RecG	NA	NA	NA	NA
WP_013067391.1\|1806137_1807550_-	methyl-accepting chemotaxis sensory transducer	A0A2H4J162	uncultured_Caudovirales_phage	8.2e-06	46.4
WP_013067392.1\|1807612_1808041_-	iron-sulfur cluster assembly scaffold protein	NA	NA	NA	NA
WP_013067393.1\|1808098_1808461_+	phosphoribosyl-AMP cyclohydrolase	NA	NA	NA	NA
WP_080514601.1\|1808776_1809307_+	Hint domain-containing protein	NA	NA	NA	NA
WP_013067395.1\|1809395_1810250_-	NAD(P)H-hydrate dehydratase	NA	NA	NA	NA
WP_013067396.1\|1810318_1810957_-	NAD(P)H-hydrate epimerase	NA	NA	NA	NA
WP_013067397.1\|1811126_1811465_+	P-II family nitrogen regulator	NA	NA	NA	NA
WP_013067398.1\|1811546_1812956_+	type I glutamate--ammonia ligase	NA	NA	NA	NA
WP_013067399.1\|1813173_1814103_+	ACP S-malonyltransferase	NA	NA	NA	NA
WP_013067400.1\|1814183_1814921_+	3-oxoacyl-ACP reductase FabG	NA	NA	NA	NA
WP_013067402.1\|1815124_1815358_+	acyl carrier protein	NA	NA	NA	NA
WP_013067403.1\|1815424_1815973_+	RNA 2',3'-cyclic phosphodiesterase	NA	NA	NA	NA
WP_013067404.1\|1816064_1817327_+	beta-ketoacyl-ACP synthase II	NA	NA	NA	NA
WP_037091459.1\|1817326_1818496_+	endolytic transglycosylase MltG	NA	NA	NA	NA
WP_013067406.1\|1818688_1819012_+	hypothetical protein	NA	NA	NA	NA
WP_031321187.1\|1818962_1820309_+	DNA-packaging protein	A0A0K1LMR9	Caulobacter_phage	2.1e-64	37.3
WP_013067408.1\|1820494_1821685_+\|portal	phage portal protein	W8ECU7	Geobacillus_phage	1.9e-64	39.9
WP_031323538.1\|1821694_1821922_+	hypothetical protein	NA	NA	NA	NA
WP_013067410.1\|1821932_1822487_+\|head,protease	HK97 family phage prohead protease	A0A0U2BX10	Paracoccus_phage	3.6e-34	54.2
WP_037091462.1\|1822554_1823715_+\|capsid	phage major capsid protein	B0VK33	Azospirillum_phage	3.7e-65	43.5
WP_013067412.1\|1823887_1824481_+	hypothetical protein	NA	NA	NA	NA
WP_013067413.1\|1824477_1824816_+\|head,tail	head-tail adaptor protein	NA	NA	NA	NA
WP_013067414.1\|1824812_1825220_+	DUF3168 domain-containing protein	NA	NA	NA	NA
WP_013067415.1\|1825260_1825674_+\|tail	phage major tail protein, TP901-1 family	NA	NA	NA	NA
WP_013067416.1\|1825681_1826008_+	gene transfer agent family protein	NA	NA	NA	NA
WP_013067417.1\|1826004_1826232_+\|tail	phage tail assembly chaperone	NA	NA	NA	NA
WP_013067418.1\|1826218_1826878_+\|tail	phage tail tape measure protein	D6PFD6	uncultured_phage	1.3e-11	32.8
WP_013067419.1\|1826888_1827521_+	DUF2460 domain-containing protein	A0A0B5A2K3	Paracoccus_phage	2.0e-57	48.8
WP_013067420.1\|1827520_1828411_+	DUF2163 domain-containing protein	A0A0K0PVK1	Roseobacter_phage	1.7e-54	40.9
WP_013067421.1\|1828407_1828860_+	peptidase	F4YXU4	Roseobacter_phage	3.3e-33	49.3
WP_013067422.1\|1828860_1832775_+\|tail	glycoside hydrolase/phage tail family protein	A0A0B5A7K5	Paracoccus_phage	8.6e-215	38.3
WP_013067423.1\|1832778_1833195_+	hypothetical protein	NA	NA	NA	NA
WP_013067424.1\|1833136_1833955_+	serine O-acetyltransferase	NA	NA	NA	NA
WP_013067425.1\|1833963_1834623_+	1-acyl-sn-glycerol-3-phosphate acyltransferase	NA	NA	NA	NA
WP_013067426.1\|1834619_1835558_+	phosphatidate cytidylyltransferase	A0A2K9L268	Tupanvirus	3.6e-10	29.1

DBSCAN-SWA_4

1839798 : 1848175

uncultured_Mediterranean_phage(33.33%)

tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_013067431.1\|1839798_1840683_-	fructose bisphosphate aldolase	A0A0K0KVJ8	Prochlorococcus_phage	3.0e-06	29.4
WP_013067432.1\|1840857_1842048_-	phosphoglycerate kinase	NA	NA	NA	NA
WP_013067433.1\|1842257_1842764_+	peptidylprolyl isomerase	A0A1B1IVS0	uncultured_Mediterranean_phage	2.1e-44	59.4
WP_013067434.1\|1842756_1843338_+	peptidylprolyl isomerase	A0A1B1IVS0	uncultured_Mediterranean_phage	1.1e-41	59.9
WP_013067435.1\|1843485_1844736_-\|tRNA	tyrosine--tRNA ligase	K4F5T3	Cronobacter_phage	3.9e-68	38.5
WP_013067436.1\|1844795_1845938_+	anhydro-N-acetylmuramic acid kinase	NA	NA	NA	NA
WP_013067437.1\|1846092_1846347_+	DUF2798 domain-containing protein	NA	NA	NA	NA
WP_013067438.1\|1846347_1846776_-	cupin domain-containing protein	A0A291ATU0	Pandoravirus	1.2e-24	41.1
WP_013067439.1\|1846900_1848175_-	phosphopyruvate hydratase	W6LP63	Streptococcus_phage	1.1e-147	61.6

DBSCAN-SWA_5

2124267 : 2157368

Rhodobacter_phage(13.33%)

head,holin,capsid,portal,tRNA,tail,terminase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_013067684.1\|2124267_2125104_-\|tRNA	tRNA glutamyl-Q(34) synthetase GluQRS	NA	NA	NA	NA
WP_013067685.1\|2125100_2126438_-\|tRNA	methylenetetrahydrofolate--tRNA-(uracil(54)- C(5))-methyltransferase (FADH(2)-oxidizing) TrmFO	NA	NA	NA	NA
WP_013067686.1\|2126505_2126856_-	hypothetical protein	NA	NA	NA	NA
WP_013067687.1\|2126916_2127621_-	hypothetical protein	NA	NA	NA	NA
WP_080514607.1\|2127650_2130443_-	DNA gyrase subunit A	G3M9Z5	Bacillus_virus	2.3e-92	36.9
WP_013067689.1\|2130552_2131038_-	disulfide bond formation protein B	NA	NA	NA	NA
WP_013067690.1\|2131040_2131625_-	DedA family protein	NA	NA	NA	NA
WP_013067691.1\|2131764_2132673_+	neutral zinc metallopeptidase	A0A1I9SA48	Rhodococcus_phage	9.5e-32	32.7
WP_013067692.1\|2132981_2133188_-	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_013067694.1\|2133935_2134133_-	hypothetical protein	NA	NA	NA	NA
WP_013067695.1\|2134129_2134339_-	hypothetical protein	NA	NA	NA	NA
WP_013067696.1\|2134424_2134718_-	DUF2312 domain-containing protein	A0A1X9HX62	Ruegeria_phage	1.3e-19	54.8
WP_013067697.1\|2134787_2135006_-	hypothetical protein	NA	NA	NA	NA
WP_013067698.1\|2135216_2135831_-	BRCT domain-containing protein	NA	NA	NA	NA
WP_148214849.1\|2136297_2136780_+	hypothetical protein	NA	NA	NA	NA
WP_013067700.1\|2136776_2137223_+	hypothetical protein	NA	NA	NA	NA
WP_013067701.1\|2137219_2137549_+	hypothetical protein	NA	NA	NA	NA
WP_050759977.1\|2137815_2138325_+	hypothetical protein	NA	NA	NA	NA
WP_013067703.1\|2138498_2139080_+	hypothetical protein	NA	NA	NA	NA
WP_013067704.1\|2139076_2139988_+	hypothetical protein	NA	NA	NA	NA
WP_013067705.1\|2140110_2140485_+	HNH endonuclease	F1C587	Cronobacter_phage	2.5e-07	40.5
WP_013067706.1\|2140607_2141048_+\|terminase	P27 family phage terminase small subunit	NA	NA	NA	NA
WP_013067707.1\|2141031_2142705_+\|terminase	phage terminase family protein	C7BGG7	Burkholderia_phage	1.1e-89	36.5
WP_115503960.1\|2142782_2143982_+\|portal	phage portal protein	Q6DMU2	Streptococcus_phage	3.7e-23	26.6
WP_013067709.1\|2143985_2144897_+	S49 family peptidase	A0A219YB02	Aeromonas_phage	4.2e-11	26.0
WP_023911500.1\|2145029_2146376_+\|capsid	phage major capsid protein	A4JX01	Burkholderia_virus	2.8e-64	42.4
WP_013067711.1\|2146430_2146991_+	hypothetical protein	NA	NA	NA	NA
WP_013067712.1\|2146990_2147923_+\|head,tail	head-tail adaptor protein	I3UM03	Rhodobacter_phage	6.1e-10	45.1
WP_013067713.1\|2147919_2148423_+	HK97 gp10 family phage protein	NA	NA	NA	NA
WP_013067714.1\|2148422_2148572_+	hypothetical protein	NA	NA	NA	NA
WP_013067715.1\|2148575_2148944_+	DUF3168 domain-containing protein	NA	NA	NA	NA
WP_013067716.1\|2148954_2149395_+	hypothetical protein	NA	NA	NA	NA
WP_013067717.1\|2149400_2149757_+	hypothetical protein	NA	NA	NA	NA
WP_013067718.1\|2149834_2150071_+	hypothetical protein	NA	NA	NA	NA
WP_013067719.1\|2150121_2153001_+	phage membrane protein	A0A1Q1PW43	Pseudoalteromonas_phage	6.7e-47	48.7
WP_013067720.1\|2152997_2153936_+	hypothetical protein	NA	NA	NA	NA
WP_013067721.1\|2153935_2154880_+	hypothetical protein	NA	NA	NA	NA
WP_013067722.1\|2154879_2155374_+	DUF4376 domain-containing protein	A0A1S5R1J2	Pseudomonas_phage	1.6e-12	47.3
WP_013067723.1\|2155435_2155756_+\|holin	phage holin family protein	I3UM16	Rhodobacter_phage	1.9e-40	80.2
WP_013067724.1\|2155757_2156432_+	TIGR02594 family protein	R9TRQ2	Rhizobium_phage	3.0e-35	41.7
WP_013067725.1\|2156450_2156798_+	hypothetical protein	A0A1B0T6I8	Thiobacimonas_phage	5.1e-10	43.8
WP_023911505.1\|2156966_2157368_+	DNA adenine methylase	A0A291AUP9	Sinorhizobium_phage	1.0e-30	64.3

DBSCAN-SWA_6

2499271 : 2508094

Erysipelothrix_phage(25.0%)

head,capsid,portal,integrase,tail

attL 2499136:2499152|attR 2516819:2516835

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
2499136:2499152	attL	NA	NA	NA	NA
WP_013068035.1\|2499271_2501080_+\|integrase	tyrosine-type recombinase/integrase	NA	NA	NA	NA
WP_013068036.1\|2501157_2502363_+\|portal	phage portal protein	A0A2K5B287	Erysipelothrix_phage	1.6e-55	35.8
WP_013068037.1\|2502355_2502676_+	gene transfer agent family protein	NA	NA	NA	NA
WP_013068038.1\|2502672_2504184_+\|capsid	phage major capsid protein	A0A0U2BX10	Paracoccus_phage	1.7e-22	34.7
WP_013068039.1\|2504187_2504826_+\|tail	phage tail assembly chaperone	NA	NA	NA	NA
WP_013068040.1\|2504828_2505173_+	HNH endonuclease	M1PLL8	Streptococcus_phage	1.1e-17	42.0
WP_013068041.1\|2505165_2505432_+	hypothetical protein	NA	NA	NA	NA
WP_131618310.1\|2505922_2506408_+	hypothetical protein	NA	NA	NA	NA
WP_013068043.1\|2506599_2506884_+\|head,tail	phage gp6-like head-tail connector protein	A0A0R6PKP1	Moraxella_phage	9.2e-10	38.6
WP_013068044.1\|2506885_2507365_+	HK97 gp10 family phage protein	NA	NA	NA	NA
WP_013068045.1\|2507357_2507780_+	DUF3168 domain-containing protein	NA	NA	NA	NA
WP_013068046.1\|2507782_2508094_+\|head	phage head closure protein	NA	NA	NA	NA
2516819:2516835	attR	NA	NA	NA	NA

DBSCAN-SWA_7

2917363 : 2925216

Acidithiobacillus_phage(66.67%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_115503985.1\|2917363_2917876_+	hypothetical protein	K4HZ96	Acidithiobacillus_phage	3.5e-23	41.7
WP_013068437.1\|2917976_2918834_+	ATP-binding protein	K4HZX9	Acidithiobacillus_phage	1.6e-60	47.8
WP_013068438.1\|2918855_2919641_+	hypothetical protein	K4ICM8	Acidithiobacillus_phage	1.4e-20	37.8
WP_013068439.1\|2919723_2919954_+	hypothetical protein	NA	NA	NA	NA
WP_031321475.1\|2920094_2920322_+	hypothetical protein	NA	NA	NA	NA
WP_013068440.1\|2920332_2920542_+	hypothetical protein	NA	NA	NA	NA
WP_013068441.1\|2920538_2921339_+	hypothetical protein	K4HZA0	Acidithiobacillus_phage	4.0e-66	53.4
WP_013068442.1\|2921331_2922651_+	AAA family ATPase	A0A0F6SJ43	Sinorhizobium_phage	5.2e-63	37.9
WP_013068443.1\|2922660_2925216_+	toprim domain-containing protein	A0A2D1GN57	Marinobacter_phage	1.8e-75	40.7

DBSCAN-SWA_8

3111015 : 3118797

Thiobacimonas_phage(33.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_013068614.1\|3111015_3111981_-	hypothetical protein	G8CLB2	Synechococcus_phage	1.2e-37	32.3
WP_013068616.1\|3112180_3112618_-	hypothetical protein	NA	NA	NA	NA
WP_013068617.1\|3112617_3113046_-	DUF1320 domain-containing protein	A0A1B0T6F3	Thiobacimonas_phage	5.4e-30	49.3
WP_013068618.1\|3113165_3113405_-	hypothetical protein	NA	NA	NA	NA
WP_013068619.1\|3113467_3114442_-	hypothetical protein	A0A219VH83	Ochrobactrum_phage	2.8e-82	51.7
WP_013068620.1\|3114465_3114849_-	DUF2190 family protein	NA	NA	NA	NA
WP_013068621.1\|3114845_3115946_-	hypothetical protein	A0A1B0T6E7	Thiobacimonas_phage	1.5e-47	39.6
WP_013068622.1\|3116051_3116507_-	phage virion morphogenesis protein	M4ST99	Rhodobacter_phage	1.7e-21	35.9
WP_023911836.1\|3116503_3116836_-	hypothetical protein	NA	NA	NA	NA
WP_013068625.1\|3116968_3117376_-	hypothetical protein	NA	NA	NA	NA
WP_013068626.1\|3117359_3117695_-	hypothetical protein	NA	NA	NA	NA
WP_013068627.1\|3117694_3117952_-	hypothetical protein	NA	NA	NA	NA
WP_013068628.1\|3118047_3118797_+	LexA family transcriptional regulator	G8GWB1	Rhodobacter_phage	6.4e-18	30.2

Anti-CRISPR protein detection

Acr_ID: NC_014034.1|WP_013068627.1|3117694_3117952_-|hypothetical-protein

Click the colored protein region to show detailed information

Acr_ID: NC_014034.1|WP_013066747.1|1089617_1089809_-|hypothetical-protein

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Acr ID

Acr position

Acr size

Homology with known anti

Neighbor HTH/AcRanker

Neighbor Aca

In prophage

Protospacer in prophage

NC_014034.1|WP_013068627.1|3117694_3117952_-|hypothetical-protein

3117694_3117952_-

85 aa aa

hit_Aca_id	identity	query_coverage	hit_coverage
gnl\|BL_ORD_ID\|85	1.0	1	1.0

3111015-3118797

NC_014034.1|WP_013066747.1|1089617_1089809_-|hypothetical-protein

1089617_1089809_-

63 aa aa

980420-1093535

yes

CRISPR ID	CRISPR type	Spacer info	Spacer location	Spacer length	Protospacer location	Mismatch
NC_014034_6	Orphan	6.5\|1434579\|35\|NC_014034\|CRT,PILER-CR,CRISPRCasFinder	1434579-1434613	35	1063808-1063774	2
NC_014034_6	Orphan	6.8\|1434778\|35\|NC_014034\|CRT,PILER-CR,CRISPRCasFinder	1434778-1434812	35	1063808-1063774	2

1. spacer 6.5|1434579|35|NC_014034|CRT,PILER-CR,CRISPRCasFinder matches to NC_014034 position: 1063808-1063774, mismatch: 2

gacgcgctgaaggagggtgatctcggtggcgcctt	CRISPR spacer
gacgcgctgaaggaaggtgatcttggtggcgcctt	Protospacer
**************.********.***********

2. spacer 6.8|1434778|35|NC_014034|CRT,PILER-CR,CRISPRCasFinder matches to NC_014034 position: 1063808-1063774, mismatch: 2

gacgcgctgaaggagggtgatctcggtggcgcctt	CRISPR spacer
gacgcgctgaaggaaggtgatcttggtggcgcctt	Protospacer
**************.********.***********

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. NC_014034

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CRISPR-Cas detection and classification

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Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection

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