CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NC_011852	Glaesserella parasuis SH0165, complete sequence	5 crisprs	WYL,DEDDh,PD-DExK,DinG,cas3,cas2	10	5	8	0

Results visualization

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CRISPR-Cas detection and classification

Crispr_ID: NC_011852_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_011852_1

225173-225888

Orphan

Consensus_repeat	Method
CCAGGACAAGCGGGTCCAGCAGGACCACGAGG	CRISPRCasFinder

10 spacers

The CRISPR arrays of NC_011852_1

>merge|NC_011852|1|225173-225888|CRISPRCasFinder
CCAGGACAAGCGGGTCCAGCAGGTCCTAGAGGTGAACCAGGACAAGCGGGTCCAGCAGGTCCTAGAGGTGAACCAGGACAAGCGGGTCCAGCAGGACCACGAGGACCGCAGGGAACAGCGGGTGCTCAGGGACCTAAGGGGGATAAAGGCGATCCAGGACAAGCGGGTCCAGCAGGACCACGAGGTCCTGCGGGTCCACCTGGTCCTGTGGGTCCAGCAGGGGCTGCTGGTCCTAAGGGGGATAAAGGCGAACCAGGACAAGCGGGTCCAGCAGGACCACGAGGCCCTGCGGGTCCTAAAGGAGATGCAGGTCCAAAAGGTGATACAGGTCAGAGAGGTGAAACTGGCTCTGCGGGTCCAGCGGGACCAAAGGGTGAACCGGGTCCTAAAGGTGAACAAGGTATTCCAGGACCTGCGGGTCCAGCGGGACCAAAGGGTGAACCGGGTCCTAAAGGTGAACAAGGTATTCCAGGCCCTGCGGGTCCAACGGGTCCAAAAGGTGATACAGGTCAGAAAGGTGAAACTGGCCCTGCGGGTCCAGCGGGACCACAAGGCCCTGCGAGTCCAACGGGATCACAAGGCCCTGCGGGTCCAACGGGTCCAGCAGGACCACAAGGACCTACGGGTCCAACGGGGCCTGCGGGTCCAACGGGACCACAAGGCCCTGCGGGTCCAGCAGGACCACAAGGACCTGCGGGTCCAGCAGGACCACAAGG

>NC_011852|1|1|225173-225888|CRISPRCasFinder
CCAGGACAAGCGGGTCCAGCAGGTCCTAGAGG	TGAACCAGGACAAGCGGGTCCAGCAGGTCCTAGAGGTGAA
CCAGGACAAGCGGGTCCAGCAGGACCACGAGG	ACCGCAGGGAACAGCGGGTGCTCAGGGACCTAAGGGGGATAAAGGCGAT
CCAGGACAAGCGGGTCCAGCAGGACCACGAGG	TCCTGCGGGTCCACCTGGTCCTGTGGGTCCAGCAGGGGCTGCTGGTCCTAAGGGGGATAAAGGCGAA
CCAGGACAAGCGGGTCCAGCAGGACCACGAGG	CCCTGCGGGTCCTAAAGGAGATGCAGGTCCAAAAGGTGATACAGGTCAGAGAGGTGAA
ACTGGCTCTGCGGGTCCAGCGGGACCAAAGGG	TGAACCGGGTCCTAAAGGTGAACAAGGTATT
CCAGGACCTGCGGGTCCAGCGGGACCAAAGGG	TGAACCGGGTCCTAAAGGTGAACAAGGTATT
CCAGGCCCTGCGGGTCCAACGGGTCCAAAAGG	TGATACAGGTCAGAAAGGTGAA
ACTGGCCCTGCGGGTCCAGCGGGACCACAAGG	CCCTGCGAGTCCAACGGGATCA
CAAGGCCCTGCGGGTCCAACGGGTCCAGCAGG	ACCACAAGGACCTACGGGTCCA
ACGGGGCCTGCGGGTCCAACGGGACCACAAGG	CCCTGCGGGTCCAGCAGGACCA
CAAGGACCTGCGGGTCCAGCAGGACCACAAGG

Protein	Signature genes	Signature genes Name	Protein_function
NC_011852.1\|WP_005710857.1\|238231_239197_+\|MucB/RseB-C-terminal-domain-containing-protein	unknown	unknown	gnl\|CDD\|236525
NC_011852.1\|WP_012621615.1\|239632_241333_+\|long-chain-fatty-acid--CoA-ligase-FadD	unknown	unknown	gnl\|CDD\|236359
NC_011852.1\|WP_012621609.1\|228656_231269_+\|type-I-DNA-topoisomerase	unknown	unknown	gnl\|CDD\|236048
NC_011852.1\|WP_012621613.1\|236578_237940_+\|bifunctional-UDP-N-acetylglucosamine-diphosphorylase/glucosamine-1-phosphate-N-acetyltransferase-GlmU	unknown	unknown	gnl\|CDD\|181867
NC_011852.1\|WP_005713820.1\|221787_222048_+\|hypothetical-protein	unknown	unknown	unknown
NC_011852.1\|WP_005710865.1\|233053_233278_-\|YejL-family-protein	unknown	unknown	gnl\|CDD\|237471
NC_011852.1\|WP_012621611.1\|233481_234183_-\|3-deoxy-D-manno-octulosonic-acid-kinase	unknown	unknown	gnl\|CDD\|234975
NC_011852.1\|WP_012621607.1\|222040_222418_+\|hypothetical-protein	unknown	unknown	unknown
NC_011852.1\|WP_012621606.1\|219086_221648_+\|translation-initiation-factor-IF-2	unknown	unknown	gnl\|CDD\|235401
NC_011852.1\|WP_005713825.1\|217060_217522_+\|ribosome-maturation-factor-RimP	unknown	unknown	gnl\|CDD\|234627
NC_011852.1\|WP_012621614.1\|239193_239622_+\|SoxR-reducing-system-RseC-family-protein	unknown	unknown	gnl\|CDD\|377263
NC_011852.1\|WP_012621610.1\|231315_233052_-\|DUF3413-domain-containing-protein	unknown	unknown	gnl\|CDD\|225625
NC_011852.1\|WP_012621608.1\|227628_228519_-\|LysR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|176114
NC_011852.1\|WP_012621605.1\|217536_219069_+\|transcription-termination/antitermination-protein-NusA	unknown	unknown	gnl\|CDD\|236410
NC_011852.1\|WP_012621612.1\|235104_236556_+\|tRNA-4-thiouridine(8)-synthase-ThiI	unknown	unknown	gnl\|CDD\|234932
NC_011852.1\|WP_012621603.1\|213586_215650_+\|iron-ABC-transporter-permease	unknown	unknown	gnl\|CDD\|224099
NC_011852.1\|WP_010785778.1\|215633_216689_+\|ferric-ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|183133
NC_011852.1\|WP_012621602.1\|212415_213333_+\|recombination-associated-protein-RdgC	unknown	unknown	gnl\|CDD\|234726
NC_011852.1\|WP_005713832.1\|210131_211262_-\|SIS-domain-containing-protein	unknown	unknown	gnl\|CDD\|131862
NC_011852.1\|WP_005713831.1\|211313_212075_-\|DeoR/GlpR-transcriptional-regulator	unknown	unknown	gnl\|CDD\|224268

Protein	Function_ID	Function_description	E-value
NC_011852.1\|WP_005710857.1\|238231_239197_+\|MucB/RseB-C-terminal-domain-containing-protein	gnl\|CDD\|236525	PRK09455, rseB, anti-sigma E factor; Provisional.	4.24e-116
NC_011852.1\|WP_012621615.1\|239632_241333_+\|long-chain-fatty-acid--CoA-ligase-FadD	gnl\|CDD\|236359	PRK08974, PRK08974, long-chain-fatty-acid--CoA ligase FadD.	0
NC_011852.1\|WP_012621609.1\|228656_231269_+\|type-I-DNA-topoisomerase	gnl\|CDD\|236048	PRK07561, PRK07561, DNA topoisomerase I subunit omega; Validated.	0
NC_011852.1\|WP_012621614.1\|239193_239622_+\|SoxR-reducing-system-RseC-family-protein	gnl\|CDD\|377263	pfam04246, RseC_MucC, Positive regulator of sigma(E), RseC/MucC. This bacterial family of integral membrane proteins represents a positive regulator of the sigma(E) transcription factor, namely RseC/MucC. The sigma(E) transcription factor is up-regulated by cell envelope protein misfolding, and regulates the expression of genes that are collectively termed ECF (devoted to Extra-Cellular Functions). In Pseudomonas aeruginosa, de-repression of sigma(E) is associated with the alginate-overproducing phenotype characteristic of chronic respiratory tract colonisation in cystic fibrosis patients. The mechanism by which RseC/MucC positively regulates the sigma(E) transcription factor is unknown. RseC is also thought to have a role in thiamine biosynthesis in Salmonella typhimurium. In addition, this family also includes an N-terminal part of RnfF, a Rhodobacter capsulatus protein, of unknown function, that is essential for nitrogen fixation. This protein also contains an ApbE domain pfam02424, which is itself involved in thiamine biosynthesis.	3.675e-31
NC_011852.1\|WP_012621613.1\|236578_237940_+\|bifunctional-UDP-N-acetylglucosamine-diphosphorylase/glucosamine-1-phosphate-N-acetyltransferase-GlmU	gnl\|CDD\|181867	PRK09451, glmU, bifunctional UDP-N-acetylglucosamine diphosphorylase/glucosamine-1-phosphate N-acetyltransferase GlmU.	0
NC_011852.1\|WP_012621611.1\|233481_234183_-\|3-deoxy-D-manno-octulosonic-acid-kinase	gnl\|CDD\|234975	PRK01723, PRK01723, 3-deoxy-D-manno-octulosonic-acid kinase; Reviewed.	8.99055e-121
NC_011852.1\|WP_005710865.1\|233053_233278_-\|YejL-family-protein	gnl\|CDD\|237471	PRK13689, PRK13689, hypothetical protein; Provisional.	5.31456e-33
NC_011852.1\|WP_012621606.1\|219086_221648_+\|translation-initiation-factor-IF-2	gnl\|CDD\|235401	PRK05306, infB, translation initiation factor IF-2; Validated.	0
NC_011852.1\|WP_005713825.1\|217060_217522_+\|ribosome-maturation-factor-RimP	gnl\|CDD\|234627	PRK00092, PRK00092, ribosome maturation protein RimP; Reviewed.	2.69303e-74
NC_011852.1\|WP_012621610.1\|231315_233052_-\|DUF3413-domain-containing-protein	gnl\|CDD\|225625	COG3083, COG3083, Predicted hydrolase of alkaline phosphatase superfamily [General function prediction only].	0
NC_011852.1\|WP_012621608.1\|227628_228519_-\|LysR-family-transcriptional-regulator	gnl\|CDD\|176114	cd08422, PBP2_CrgA_like, The C-terminal substrate binding domain of LysR-type transcriptional regulator CrgA and its related homologs, contains the type 2 periplasmic binding domain. This CD includes the substrate binding domain of LysR-type transcriptional regulator (LTTR) CrgA and its related homologs. The LTTRs are acting as both auto-repressors and activators of target promoters, controlling operons involved in a wide variety of cellular processes such as amino acid biosynthesis, CO2 fixation, antibiotic resistance, degradation of aromatic compounds, nodule formation of nitrogen-fixing bacteria, and synthesis of virulence factors, to name a few. In contrast to the tetrameric form of other LTTRs, CrgA from Neisseria meningitides assembles into an octameric ring, which can bind up to four 63-bp DNA oligonucleotides. Phylogenetic cluster analysis further showed that the CrgA-like regulators form a subclass of the LTTRs that function as octamers. The CrgA is an auto-repressor of its own gene and activates the expression of the mdaB gene which coding for an NADPH-quinone reductase and that its action is increased by MBL (alpha-methylene-gamma-butyrolactone), an inducer of NADPH-quinone oxidoreductase. The structural topology of this substrate-binding domain is most similar to that of the type 2 periplasmic binding proteins (PBP2), which are responsible for the uptake of a variety of substrates such as phosphate, sulfate, polysaccharides, lysine/arginine/ornithine, and histidine. The PBP2 bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap. After binding their specific ligand with high affinity, they can interact with a cognate membrane transport complex comprised of two integral membrane domains and two cytoplasmically located ATPase domains. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis.	1.93895e-81
NC_011852.1\|WP_012621605.1\|217536_219069_+\|transcription-termination/antitermination-protein-NusA	gnl\|CDD\|236410	PRK09202, nusA, transcription elongation factor NusA; Validated.	0
NC_011852.1\|WP_012621612.1\|235104_236556_+\|tRNA-4-thiouridine(8)-synthase-ThiI	gnl\|CDD\|234932	PRK01269, PRK01269, tRNA s(4)U8 sulfurtransferase; Provisional.	0
NC_011852.1\|WP_012621603.1\|213586_215650_+\|iron-ABC-transporter-permease	gnl\|CDD\|224099	COG1178, ThiP, ABC-type Fe3+ transport system, permease component [Inorganic ion transport and metabolism].	3.23361e-132
NC_011852.1\|WP_010785778.1\|215633_216689_+\|ferric-ABC-transporter-ATP-binding-protein	gnl\|CDD\|183133	PRK11432, fbpC, ferric ABC transporter ATP-binding protein.	0
NC_011852.1\|WP_012621602.1\|212415_213333_+\|recombination-associated-protein-RdgC	gnl\|CDD\|234726	PRK00321, rdgC, recombination associated protein; Reviewed.	3.99663e-156
NC_011852.1\|WP_005713832.1\|210131_211262_-\|SIS-domain-containing-protein	gnl\|CDD\|131862	TIGR02815, agaS_fam, putative sugar isomerase, AgaS family. Some members of this protein family are found in regions associated with N-acetyl-galactosamine and galactosamine untilization and are suggested to be isomerases.	4.19956e-150
NC_011852.1\|WP_005713831.1\|211313_212075_-\|DeoR/GlpR-transcriptional-regulator	gnl\|CDD\|224268	COG1349, GlpR, Transcriptional regulators of sugar metabolism [Transcription / Carbohydrate transport and metabolism].	9.78371e-89

>NC_011852.1|WP_012621607.1|222040_222418_+|hypothetical-protein
MANLTIEYGSLFRKEFANFPVKDQDAIVEFVEHILKFGFTNLEGRNKSSDNVHKNDPHFAQKVKYARENHLWHYHIGILAFDLSKPFGDRTSEYVLHYQRFSDRIKIVDYSAHPPFNLPTASYLR
>NC_011852.1|WP_005713820.1|221787_222048_+|hypothetical-protein
MAQIYIQSDYFHQQMACIVQAIQSGMEKQALISYVQNVEKQIADKVEEPAFNYDLERMKAHVESETIEMPSDLTSAKAIKEWLLNG
>NC_011852.1|WP_012621606.1|219086_221648_+|translation-initiation-factor-IF-2
MSENEIKTDAPKKLSLQRRTKTTVSGTTAGGKAKEVQVEVRKSRKVDTEAAKKAQEEALKSKQEAEAKAKEEAKKAEAAKAEEAKKAVHQVPVMPNKQPKPAQPKAEAQPKQEKAVDPEKEAKRKEEAELRRKQEEVARQKAEMDAKRAAENARRLAENARRLAENARRLAEIAREEAIENGEDYEDDRFTSKYALEAERDSERRSEGNRGRGKGGVAKTKKGGRDDENGSKNERQSDRRNQKDTKGKGKHAKKGSALQQAFTKPAQAVTRDVVIGETITVAELANKMAVKATEIIKTMMKMGEMVTINQVIDQETAQLVAEEMGHKVILRKENELEEAILEDRDLHAEKVTRAPVVTIMGHVDHGKTSLLDYIRKAKVAAGEAGGITQHIGAYHVETDDGKMITFLDTPGHAAFTSMRARGAKATDIVVLVVAADDGVMPQTIEAIQHAKAAGAPIVVAVNKIDKPEANLERVEQELLQHEVISEKFGGDVQFVPVSAKKGMGIDDLLEAILLQSEVLELSAVKEGMASGVVIESYLDKGRGPVATILVQSGTLNKGDIVLCGFEYGRVRAMRDENGKDIESAGPSIPVEVLGLSGVPAAGDEATVVRDEKKVREVALYRQGKFRDVKLARQQKAKLENMFSNMAEGDVAELNVIVKADVQGSVEAIVQSLHELSTAEVKVKVVGSGVGGITETDATLAAASNAIVLGFNVRADASARRIIESENIDLRYYSIIYELLNEIKAAMSGMLQPEFKQEIIGLAEVRDVFRHPKFGAIAGCMVTEGIVKRNNPIRVLRDNVVIFEGELESLRRFKDDVSEVRNGMECGIGVKNYNDVKVGDQIEVFEVVEIKRSI
>NC_011852.1|WP_012621605.1|217536_219069_+|transcription-termination/antitermination-protein-NusA
MSKEILLAAEAVSNEKLLPKDAIFEALETALAISTKKKAAAEREDRKTGNGIDIDVRVVIDRKTGAFTTYRRWLVVEKVHHHTREITLEAAQFEDPNIQLGDYVEDEIESIAFDRITMQTARQVITMKIREAERNKVIEQFRSEEGKIVIGTVKKVSRESIILELAGKKDDTTKAEAVIVREDMLPRENFRPGDRVRGVLYAIKPESKGPQLFVTRAKPVMLQELFKLEVPEIGEEVIEIKGASRDPGSRAKIAVKSNDKRIDPVGACVGMRGARVQAITNELGGERVDIVLWDDNPAQFLINAMAPADVSSIVVDEDNHSMDIAVEANALAQAIGRNGQNVRLATQLTGWTLNVMTTDELEKKHQAEDNKVINLFMDALEIDEEFAHLLIEEGFTSLEEIAYVPVKELTAIDGLEDEDLVEELQVRAKNAITAKALAEEEALKQAHIEDKLLNLEGMDRHIAFKLAEKQITTLEDLAEQGVDDLADIEELTAEKAAELIMAARQICWFS
>NC_011852.1|WP_005713825.1|217060_217522_+|ribosome-maturation-factor-RimP
MATLEQKLQELVADPIDAMGFELVGVECQRAGRFLTVRLYIDKEGGVTVDDCSDVSRQVSAIFDVEDPIADKYNLEVSSPGLDRPLFTLAHYQRFVGREIVVHLRIPMLDRRKWQGELVSVEGDLITLKVDGNLQAFAFGNIQKANLIPVFNF
>NC_011852.1|WP_010785778.1|215633_216689_+|ferric-ABC-transporter-ATP-binding-protein
MEQKNDFLVLKNISKSFGKHRVIDNLNFSIKQGTMVTLLGPSGCGKTTVLRLVAGLESPTAGQIFIDGEDVTHNATQQRDICIVFQSYALFPHMSIGENVEYGLKMQGVSKEERKQRVKEALELVDLIGFEDRYVDQISGGQQQRVALARALILKPKVLLFDEPLSSLDANLRRSMREKIRELQQRLNITSLYVTHDQSEAFAVSDEVIVMDQGTIMQKDTAKNLYLQPNSLFVAHFMGESTIFSGKRQGNQINIGEFSFTLENAARFQVPDGDCLVGLRPESIRLLSDGTAAQYCEIKQAVYMGNHWEITALWQGKTLMINLNPEDYDESQRNCYIEIKNKGVFLLKDNA
>NC_011852.1|WP_012621603.1|213586_215650_+|iron-ABC-transporter-permease
MQTFFFRHSLTWVIFAFLGFCFFPVKALQYGLFGATSAEFQQAMGWNDINLTWIWFFPLLLYLYPNKTPSTLRSKCELFGAVGLFLFIFLSAILAKISLGYAVFFLIVALIALATNALAELKIMQGDRFIIASLISIILLIFFFMVYPTLAIFISMFYDGSEFVPSQVLSILQQPYVLRVIGNSLSVATTVGIVSTLFGLAFALYTTRIAKRTAFIGKIFSILPIVTPPFVVGLGVTLMLGRSGYVTAFLVDHLGFSNNWLYGFTGIVIAHTLALTPMSFMILDGALKSIHPSVEEAAYTLRSNRYQAFFYIIFPLLKPALANSFLVVVIQSLADFSTPLVLGGSFDVIATQIYFYIAGSQLDYASASTLGVILLLFSLTIFVVQYLWIGNRSYITVSGKSYRGDVQELPSGMKWAIICTLGFWVLFNFVLYGSIFYGSFTVSWGIDHTLTFNNYLNLFGQGFNSGAWPSLIQTVIFAASAAPITAIFGLLIAYITVRRDFKGKKPLEFLTLLCFAVPGTVAGVSYILAFNHQPIYLTGTGLIIILSMVMRNMPVGMRAAIAGLRQLDKALDEASLSLKAGTLKTICFVALPLLKPALLSALVTSFVRSMTTVSAIIFLVTADTRVATSYILNRVEDGEYGMAIAYGSMLIVVMLAMIFLFDWLVGDTHTARSKQKDEFGEKNGTKK
>NC_011852.1|WP_012621602.1|212415_213333_+|recombination-associated-protein-RdgC
MTYWFKNVMIYRLTSELRFTSSELDAQLQQTKFTPCQQSDIQKFGWSSPLAGSELLHFAQGQQFLLVSHKEEKLLPAHVVKKETENRIEALEQKEQRKLKKTEKQAIKDDVVAMLLPRAFSKHQFTAIWLDLDKQLVYVDSGSAKRAEDTLALLRKSLGSLPVVPISFTLQPSEVMTNWVAKGHTPSWLTLLEEAELKSFDTDSVIRCKRQDLESDEISQHLQAGKFVTKLALDWENHFSFVLNEDATLARVKFADEVREKNDDILKEDKAQRFDADFLLMTEELRLFTEKLTEEFGGVNSLLSF
>NC_011852.1|WP_005713831.1|211313_212075_-|DeoR/GlpR-transcriptional-regulator
MKSSVERRSDILALLQKTGSHRVEALSQHFGVSTVTIRSDLNVLEQQGYITRSHGFAVLNSRLIAELSIADKSNNYPELKQQIGHLAASLLKEGEKVILDSGTTTKAIVSAIGDLNLTVLTNGLDVAMALVSCPNVEVRMTGGVLRKNAMSFSGVMADNNLQHYRFDKVFLGVDGFDLQKGVTTFNEQEAQLNRLMCDAADQVIVVTDSSKFGQYSHFVICQANQIDVLVTDNKIPLSYREYLENVGVQVLIA
>NC_011852.1|WP_005713832.1|210131_211262_-|SIS-domain-containing-protein
MILNIANQTLEKQNAFWTAKEIAQQPATWRETVSIVKSSLVIPFLQPLVEYAKQGELRVIFTGAGTSAFIGEVVAPILSQHLGCAVEAIASTDLVSNPYQYLFSDKPTLLVSFARSGNSPESIGAVELVDEIVEEAYHLTITNNVNGALFKKCQQDPTAYPLALPESTHDKGFAMTSSASNMMLAALVAFLPDVFDDNWVEGAISVTEQLLEQDLLEIQRLAHLPLKRIVYLGSGHFQGLARETSLKLLELTAGERLGFFESSMGFRHGPKSLVQDETLIFIFLSQQPYTAQYDRDLYQELVRDGKAKEILLLGDTSGLIKAEICKLDDAARIFPFLVIGQLYSFYSSLYLGYTTDNPCPTGEVNRVVQGVTIYPY
>NC_011852.1|WP_012621608.1|227628_228519_-|LysR-family-transcriptional-regulator
MDKLKAINLFCKVIETQSFTQAAQQEQISLAMASKLVAQLEEHLNVRLLQRTTRRISPTEAGLLFYQRCQPILNELKDAEACVTNITSTLQGKLTMSLPMDFGSRFVAPHLHRFTETYPHLQLNLEFSDRRVDVVAEGYDLVLRIGKLEDSSIVAKRIAQAQHLIVASPRYLEKFGTPQTAWELQQHQCLRYESQTLWQFNENGHKIKFKPQSQVYSNNGYALVQMARAGHGIINIPKFLLKDELASGELIPILPHLEQELSDISLLYPNRRYLSPKVKVTIEFFSQLMQEQKIHL
>NC_011852.1|WP_012621609.1|228656_231269_+|type-I-DNA-topoisomerase
MGKSLVIVESPAKAKTINKYLGSDFVVKSSVGHIRDLPTSGAEKEEKTEKAKAVSTKGMTAEQKALVKSEKERTALVKRMGVDPYHDWNATYQILPGKEKVVSELKSLAKKADHIYLATDLDREGEAIAWHLREVIGGENERFSRVVFNEITKNAIKQAFEKPEQLNMDRVNAQQTRRFLDRVVGFMVSPLLWKKVARGLSAGRVQSVAVKLLVEREREIKAFQPEEFWDILAKTSAKKGDLALELVQHKGKKFSVKNQKEAEQAVKSLQNSAFIVTEIDKKPTSSRAKAPFITSTLQQTASTRLGFSVKKTMMLAQRLYEAGYITYMRTDSTNLSQDALTMARSYIEKQFGDRYLPEKPNFYASKEKAQEAHEAIRPSDVMVKMQDLSGMEKDAERLYDLIWRQFLACQMTPAEYDSTSLTVTAGDYELKTKGRVLRFDGWTKVLPIQGKTAEDQELPEVSLNETLKLNAVEPSQHFTKPPARYSEAALVKELEKRGIGRPSTYAAIISTIQERGYVRVENRRFYAEKMGEIVTDRLNEAFSDLMNYDFTANMEDTLDQIASGNSNWKVELNRFFADFSEKLTTAELDELEGGMRSNNLVATDIHCPTCQRQMAIRTASTGVFLGCTGYALSPKERCKTTINLIPEAELLNVLDEDSETNALMKRKRCPKCDTAMDSYVIDPQRKIHICGNNPNCDGYVIEEGSFKIKGYDGPIVECDKCGSDMHLKLGRFGKYMGCTNCDNTRKILKNGEVAPPREEPVAFPELKCEKSDAYFVLRDGASGVFMSAHNFPKSRETRAPKVAELALYRDRLPEKLQYLADAPQQDPEGNEAIIRFSRKEKRQYVTSEKNGKATKWIVDYLDGKWVERHR
>NC_011852.1|WP_012621610.1|231315_233052_-|DUF3413-domain-containing-protein
MLNQLRYLLPENSRQYREEISQRISWGHWFALFNIVVTLLISSRYAFNADWPNTLFGKLYFFISLFGHFSFVVFALYLLLLFPLSFLIKNNRAFRSISVIFATIGMTILLVDTEVFKRFYLHLSPLVWDLLVNPNDDGELTRQWQLLFVPMPLILLAEMLYSRWCWNKLRSFNRQKWGKYVAMLFLACFTATHLLYAWADMTLYRPITAQKANYPLSYPMTARSFLEKHGLIDRAVLEQQIEESGRLDTFYLNYPRKALQFVEPQHKPNVLFINLSGLKNEAITAETMPSLYQVSQNARRFTQHYNSSDSLSGSIVGLFYGLSGRYLDAILNEKAPSLLIARLQQLNYQFGLFSHNGFAEPIYHRALFAHFKLPKTKSNLEAIEKWKNWIGKRSDKAFFSYLDLQLPAGIDYAQQSKSLDWQFNDIWQTLEQQGLAQSTLIVITSDIAEQAVTSDNSFAQARIQVPMLIYWQGDNRTYSLPSSHLDIAPTLLSQFFGVTSPISDYAQGIDLTKENSRKWLLASNYKWNVAIMPNGEQFHINRKGDFEHFDLQGEKQTSRPPLALFLQLIQQSNLFIEK
>NC_011852.1|WP_005710865.1|233053_233278_-|YejL-family-protein
MATKSKYQDKQIEALLNDLIVTLEKHKAPVDLSLMALGNMITNILVTNVQSPQQREVLAEAFSSALKNSLKSAK
>NC_011852.1|WP_012621611.1|233481_234183_-|3-deoxy-D-manno-octulosonic-acid-kinase
MYYHFNTQLVADEKQSFVQQLLDCKDFSQSNRLLGSSKGRGTTWFLNTEKELGVNSVLRHYYRGGLFGKLVKDRYLFQSHEKTRAMQEFRLLAQLSKWQIPVPRPIAIRVKRQCCFYQADILLEKIADTQDLSQYLQTKSLTPAQYQQIGQLIRLLHDHQVHHSDLNIHNILIDNQGKFWLIDFDKCQIQQGNEWKQGNLDRLLRSFNKEKGRLSIHFYPQDWEILYQSYMNN
>NC_011852.1|WP_012621612.1|235104_236556_+|tRNA-4-thiouridine(8)-synthase-ThiI
MKFIIKLFPEIMIKSDSVRKRFIKILTSNIRNVLLRETENVAVIRNWDFIEVRAKVAEEAPLVLDLLKRTPGVHHILEVEEMPFTTMHDIFEHTLAKVKGELEGKTFCVRVRRKGKHDFRSLDVERYVGGGLNQHIESASVKLTNPDVTVRIDIDHDKMLLIKARHEGLGGYPIGTQEDVLSLISGGFDSGVSSYMLIRRGSRVHYCFFNLGGAAHEIGVKQMAYHIWSRYSSSHKVRFVAINFENVVGEILEKVDNGQMGVVLKRMMVRAASKIAERFDIQAIVTGEALGQVSSQTLTNLRLIDKTSDTLVLRPLITHDKEQIIAMAKEIGTDDIAKSMPEFCGVISKNPTVKAIESKIIEEEGNFNFDVLEQAVQNAHYLDIREIAQQTEKEVVSVETTSELGENDVILDIRSPEEVDEKPFSLEGVEVKELPFYKLSNHFGNLDQSKTYLLYCQRGVMSKLQALYLKENGFSNIKVFSIL
>NC_011852.1|WP_012621613.1|236578_237940_+|bifunctional-UDP-N-acetylglucosamine-diphosphorylase/glucosamine-1-phosphate-N-acetyltransferase-GlmU
MTQLSVVILAAGKGTRMYSDLPKVLHPIAGKPMVKHVIDTAKQLSAKQIHLIYGHGGDLLQQRLSAEPVNWVLQAEQLGTGHAMQQAAPFFADDENILMLYGDAPLITATTLEKLIAAKPENGIALLTVVLDNPTGYGRIIRENGSVVAIVEQKDANPEQLKIQEINTGVMVASGASFKKWLSQLDNNNAQGEYYITDVIAMANRDGYKVEAVQATNLMEVEGANNRLQLAALERYYQKIQAEKLLLAGVTIIDPARFDLRGTVTHGKDVVIDVNVILEGSIQLGNNVKIGAGSVLKNVVLGDNVEIKPYSVLEDSVIGESADVGPFARLRPGTELAAKAHVGNFVEIKKSTIGEGSKVGHLTYIGDSEIGANVNIGAGTITCNYDGANKFKTIIGDNVFVGSDTQLVAPVTVASGATIGAGSTITKDVAADELVITRVPQRHIQGWQRPTKK
>NC_011852.1|WP_005710857.1|238231_239197_+|MucB/RseB-C-terminal-domain-containing-protein
MKKYITLFVSLFLSITGFAQPLSTPLAYLTAMNKAHQTLNYEQLYIFQKGDDVTSLRYRHAYDNGQEYAQLLHLDATREEMILREDVVGYFGDYQPFSLKTPHILDDFPTVVYSNFSQLEGYAFLDNGKSRVADRIARVIRIVPRDDFRYQYMLWIDEENHLLLQSHLLDRDNNVLEQFRTIQSVVDEQLLYIVEPIRTLILPTLLQTKVHSELKPLEWQLKWVPNGFKQVASGQQNLSEVLAQDEQIESRLYSDGLFSFTVYLVQNKGISFQDQFWREGKTSVYSQTIGDKDVIIVGEIPLASARHIVQEIEFSSQGEEQ
>NC_011852.1|WP_012621614.1|239193_239622_+|SoxR-reducing-system-RseC-family-protein
MMIEQATVIQYQNGIARVQCQAKSSCGSCVAQSHCGSKALSALAGEKFAPQFDLVVAMPLQVGDKVKIGLAERSLLEGVFWLYAVPLFVIVLSTLVLSQWLNHELWVAAGVLCTTAVTFFMIKRAVAQKSQAQFIPVFLGKV
>NC_011852.1|WP_012621615.1|239632_241333_+|long-chain-fatty-acid--CoA-ligase-FadD
MEKIWFDNYPAEAERTLDVEPYESLVEMFEKAVQRHPDIPAYINMGQVLTFRKLEERSRAFAAYLQNELRLEKGERIALMIPNLLQYPIALFGALRAGLVVVNVNPLYTPRELEYQLNDSGAKAIVVVSNFAATLEKVVFNTQVKHVILTRMGDQLSFGKRTLVNFVVKYVKKLVPKYKLPHAVSFRETLSIGKQRQYVRPTLYKNDLAFLQYTGGTTGVAKGAMLSHSNVIANILQAKWVAYPLIQRSQERIGVIALPLYHVFALTVNCLLFIELGVTGLLITNPRDIPAFVKELKKYPVMAITGVNTLFNALLNNPQLKEVDFSNLKLSVGGGAAIQRAVADRWHKTTGCHIIEGYGMTECSPLIAATRNDSTEYSGSIGVPVPNTDIRIVDDAGNDLPIGERGELWVKGPQVMQGYWQRPEDTAEVLKDGWMATGDIVELGQDLNLRIVDRKKDMIIVSGFNVYPNEIEDVVALHPKVNEVVVVGIPSEVSGESIKVFVTKKDESLTREELRNHCRQHLTGYKIPREIEFRDELPKSNVGKILRRVLRDEEVARVKSQMEGKL

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Crispr_ID: NC_011852_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_011852_2

336328-336548

Orphan

Consensus_repeat	Method
CTTCATTTCTTCTGTTGGATTTT	CRISPRCasFinder

3 spacers

WYL

The CRISPR arrays of NC_011852_2

>merge|NC_011852|2|336328-336548|CRISPRCasFinder
TTTCATTTCTTCTGTTGGATTTTTTATATATCGAATAGCATAACCATTTTCTTTAATCGCAAGCAACTTCATTTCTTCTGTTGGATTTTCAATATATTGAATAGCACAACCATCCACTTTTACTGCAGCTAGCTTCGTTTCTTCTGTTGGATTTTTGAAAATATTAAAAGGCCAACCACGTTGTATAAGCTCTACTGGTGTCATATCTTCTATACGCTTTT

>NC_011852|2|2|336328-336548|CRISPRCasFinder
TTTCATTTCTTCTGTTGGATTTT	TTATATATCGAATAGCATAACCATTTTCTTTAATCGCAAGCAA
CTTCATTTCTTCTGTTGGATTTT	CAATATATTGAATAGCACAACCATCCACTTTTACTGCAGCTAG
CTTCGTTTCTTCTGTTGGATTTT	TGAAAATATTAAAAGGCCAACCACGTTGTATAAGCTCTACTGG
TGTCATATCTTCTATACGCTTTT

Protein	Signature genes	Signature genes Name	Protein_function
NC_011852.1\|WP_005713479.1\|334939_335326_-\|hypothetical-protein	unknown	unknown	unknown
NC_011852.1\|WP_012621663.1\|342199_342766_+\|UbiX-family-flavin-prenyltransferase	unknown	unknown	gnl\|CDD\|223241
NC_011852.1\|WP_012621660.1\|328461_330033_+\|glutamine-hydrolyzing-GMP-synthase	unknown	unknown	gnl\|CDD\|234614
NC_011852.1\|WP_010786833.1\|332154_333801_-\|DNA-repair-ATPase	unknown	unknown	gnl\|CDD\|224117
NC_011852.1\|WP_041603106.1\|342766_343204_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|235127
NC_011852.1\|WP_005713464.1\|338080_338425_+\|helix-turn-helix-transcriptional-regulator	unknown	unknown	gnl\|CDD\|238045
NC_011852.1\|WP_010786834.1\|331900_332158_-\|YkgJ-family-cysteine-cluster-protein	unknown	unknown	gnl\|CDD\|308985
NC_011852.1\|WP_005713493.1\|331233_331452_-\|hypothetical-protein	unknown	unknown	unknown
NC_011852.1\|WP_041603105.1\|341068_342019_-\|tRNA-2-thiocytidine(32)-synthetase-TtcA	unknown	unknown	gnl\|CDD\|236737
NC_011852.1\|WP_005713468.1\|336975_337863_-\|WYL-domain-containing-protein	WYL	COG2378_WYL_CAS-I:CAS-III	gnl\|CDD\|379100
NC_011852.1\|WP_005713471.1\|336628_336967_-\|hypothetical-protein	unknown	unknown	unknown
NC_011852.1\|WP_010786832.1\|333847_334924_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|237537
NC_011852.1\|WP_010786825.1\|346240_347080_+\|NADPH-dependent-7-cyano-7-deazaguanine-reductase-QueF	unknown	unknown	gnl\|CDD\|236986
NC_011852.1\|WP_005713459.1\|339384_340761_-\|Na+/H+-antiporter-family-protein	unknown	unknown	gnl\|CDD\|224967
NC_011852.1\|WP_005713476.1\|335352_336066_-\|DUF3944-domain-containing-protein	unknown	unknown	gnl\|CDD\|227078
NC_011852.1\|WP_049753210.1\|343395_346224_+\|bifunctional-[glutamate--ammonia-ligase]-adenylyl-L-tyrosine-phosphorylase/[glutamate--ammonia-ligase]-adenylyltransferase	unknown	unknown	gnl\|CDD\|236836
NC_011852.1\|WP_005712315.1\|330167_330638_+\|DUF4102-domain-containing-protein	unknown	unknown	gnl\|CDD\|379139
NC_011852.1\|WP_005713461.1\|338465_339269_-\|exodeoxyribonuclease-III	unknown	unknown	gnl\|CDD\|236970
NC_011852.1\|WP_010786835.1\|331504_331876_-\|hypothetical-protein	unknown	unknown	unknown
NC_011852.1\|WP_041603104.1\|327061_327694_+\|DUF1919-domain-containing-protein	unknown	unknown	gnl\|CDD\|370199

Protein	Function_ID	Function_description	E-value
NC_011852.1\|WP_005713468.1\|336975_337863_-\|WYL-domain-containing-protein	gnl\|CDD\|379100	pfam13280, WYL, WYL domain. WYL is a Sm-like SH3 beta-barrel fold containing domain. It is a member of the WYL-like superfamily, named for three conserved amino acids found in a subset of the superfamily. However, these residues are not strongly conserved throughout the family. Rather, the conservation pattern includes four basic residues and a position often occupied by a cysteine, which are predicted to line a ligand-binding groove typical of the Sm-like SH3 beta-barrels. A WYL domain protein (sll7009) is a negative regulator of the I-D CRISPR-Cas system in Synechocystis sp. It is predicted to be a ligand-sensing domain that could bind negatively charged ligands, such as nucleotides or nucleic acid fragments, to regulate CRISPR-Cas and other defense systems such as the abortive infection AbiG system.	3.39294e-25
NC_011852.1\|WP_012621660.1\|328461_330033_+\|glutamine-hydrolyzing-GMP-synthase	gnl\|CDD\|234614	PRK00074, guaA, GMP synthase; Reviewed.	0
NC_011852.1\|WP_010786833.1\|332154_333801_-\|DNA-repair-ATPase	gnl\|CDD\|224117	COG1196, Smc, Chromosome segregation ATPases [Cell division and chromosome partitioning].	0.00236377
NC_011852.1\|WP_041603106.1\|342766_343204_+\|hypothetical-protein	gnl\|CDD\|235127	PRK03467, PRK03467, hypothetical protein; Provisional.	3.94735e-43
NC_011852.1\|WP_005713464.1\|338080_338425_+\|helix-turn-helix-transcriptional-regulator	gnl\|CDD\|238045	cd00093, HTH_XRE, Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators.	1.90957e-12
NC_011852.1\|WP_010786834.1\|331900_332158_-\|YkgJ-family-cysteine-cluster-protein	gnl\|CDD\|308985	pfam03692, CxxCxxCC, Putative zinc- or iron-chelating domain. This family of proteins contains 8 conserved cysteines. It has in the past been annotated as being one of the complex of proteins of the flagellar Fli complex. However this was due to a mis-annotation of the original Salmonella LT2 Genbank entry of 'fliB'. With all its conserved cysteines it is possibly a domain that chelates iron or zinc ions.	2.31805e-07
NC_011852.1\|WP_012621663.1\|342199_342766_+\|UbiX-family-flavin-prenyltransferase	gnl\|CDD\|223241	COG0163, UbiX family flavin prenyltransferase [Coenzyme transport and metabolism].	1.33386e-102
NC_011852.1\|WP_041603105.1\|341068_342019_-\|tRNA-2-thiocytidine(32)-synthetase-TtcA	gnl\|CDD\|236737	PRK10696, PRK10696, tRNA 2-thiocytidine biosynthesis protein TtcA; Provisional.	0
NC_011852.1\|WP_010786825.1\|346240_347080_+\|NADPH-dependent-7-cyano-7-deazaguanine-reductase-QueF	gnl\|CDD\|236986	PRK11792, queF, 7-cyano-7-deazaguanine reductase; Provisional.	0
NC_011852.1\|WP_005713459.1\|339384_340761_-\|Na+/H+-antiporter-family-protein	gnl\|CDD\|224967	COG2056, COG2056, Predicted permease [General function prediction only].	0
NC_011852.1\|WP_005713476.1\|335352_336066_-\|DUF3944-domain-containing-protein	gnl\|CDD\|227078	COG4735, COG4735, Uncharacterized protein conserved in bacteria [Function unknown].	1.50452e-33
NC_011852.1\|WP_049753210.1\|343395_346224_+\|bifunctional-[glutamate--ammonia-ligase]-adenylyl-L-tyrosine-phosphorylase/[glutamate--ammonia-ligase]-adenylyltransferase	gnl\|CDD\|236836	PRK11072, PRK11072, bifunctional [glutamate--ammonia ligase]-adenylyl-L-tyrosine phosphorylase/[glutamate--ammonia-ligase] adenylyltransferase.	0
NC_011852.1\|WP_005712315.1\|330167_330638_+\|DUF4102-domain-containing-protein	gnl\|CDD\|379139	pfam13356, Arm-DNA-bind_3, Arm DNA-binding domain. This DNA-binding domain is found at the N-terminus of a wide variety of phage integrase proteins.	5.39647e-21
NC_011852.1\|WP_005713461.1\|338465_339269_-\|exodeoxyribonuclease-III	gnl\|CDD\|236970	PRK11756, PRK11756, exonuclease III; Provisional.	0
NC_011852.1\|WP_010786832.1\|333847_334924_-\|hypothetical-protein	gnl\|CDD\|237537	PRK13875, PRK13875, conjugal transfer protein TrbL; Provisional.	7.09125e-05
NC_011852.1\|WP_041603104.1\|327061_327694_+\|DUF1919-domain-containing-protein	gnl\|CDD\|370199	pfam08942, DUF1919, Domain of unknown function (DUF1919). This domain has no known function. It is found in various hypothetical and putative bacterial proteins.	2.68286e-96

>NC_011852.1|WP_005713476.1|335352_336066_-|DUF3944-domain-containing-protein
MAYVYDVDLEFLAQCTNEDLQPLVDILTKDKDGKKRYTEGLTSSRVYKVFYPDHNLYWKEIAEEIQKFGANTIATLFRLGKGVSYKTILIEVCEKMKVNFNKESSTELIEKHLLDKVLTSAIEELSEDDLKKLAEELKIPATHLGKQSLTALVLVELNSLLSTPVLWKTIHTMFPQTIGTLLAGTALGRILGFATGPIGWGITGIWALKDISGPATRVTVPAVIQIAFLRKKYSINN
>NC_011852.1|WP_005713479.1|334939_335326_-|hypothetical-protein
MFVQNLTAEQQSALIYLAHEIARADGSSDELQLGMVEILTKQSEDGVTEKAITVDELVTLFTTERAKCSLLLELLGVAHANEEYHLSEKDMIAGYARKLGISNEKLNALESWVEKQFALSREVTLLLD
>NC_011852.1|WP_010786832.1|333847_334924_-|hypothetical-protein
MPLPFILAGAAAVTIGTGIKKGIDGFKDNSAAKDITEAAESLYDTEKKLFDEQDAATNASLESLGQLQLSIGSDFAEFKRISELLLEKLAQHKEAKDLQINIPKNELDKIEGIAFSAVAYLGQLAGGAAIGAGAAYAVYGGVMALAAASTGTPIAALSGAAAYKATMAAIGGGAISAGGFGMAGGAAILGGAVVAPIVLVAGLAFAKHSEKKLESARDYRTQVKNAVSSMKLGRHHLKETEEYSNKIYKELNRVYQIFGQYFQDLKNMDTLVRNGVDINTISSAIIKIVDNGYKVAAILTDIITTPLFKPKKDDNGELVKNKEDTVEFETDKDGMKVINKEDIDAHITLSTYKSKDFE
>NC_011852.1|WP_010786833.1|332154_333801_-|DNA-repair-ATPase
MSNVLMTKPEFDWTGELEKTVVNSLVTTFGLDFLLFEDKRGGDVDTINNVRQGIYATDEAKNAYDSRGDYDGSIYRTHEDYKEKGRKDKKAIENGELYDAYNKNNKLNRKREIDHTISAKEIHDDAGRVLANVDGVKIANRDYNLNTTTWDVNNPKREHSVTKFINEIAPQKIKQLEKTIEHKKNQISKITGDTPEERHKREKLSKEIETHENQKKELESILENKEDILAADKKAREEYNKEINWKYYTSSKFFKSTALAAGRAGLKMGTRQALGLVLAEIWFELRERIPEIYQSLKQNFTIIKFLEKIAKTLSNIFERVKERFKDLLTAFKDGAIAGFFSNISTTVMNIFLVSEKMVMKLIREMWNSIVSAIKLITFNPDNLNAKELFKGVLKILSAGLSVLLGTMLNSHLNTILIFPMGDLIAAFVSALATGLMTCAFAYFIENGLSFKKLWEIINSYKNKYELMTEHMKEINAELDRYLLEWAKIEFNLNPNEIAVFVDSLEACNSELERSIVLEKEIHRRNIELPYESGNEQSTRNWLASLAVK
>NC_011852.1|WP_010786834.1|331900_332158_-|YkgJ-family-cysteine-cluster-protein
MSSLASFPCNACGKCCRRVNLSEQTAYLDRGDGVCHHFDEQTNLCKIYENRPLVCRVEDYYKAHLSHLYSWEEFVKLNLEICNKL
>NC_011852.1|WP_010786835.1|331504_331876_-|hypothetical-protein
MNFFDILGRVAKAISRSVGNSMENHIIELWNKLKNLDNDRLISFINSKDTLNTQVYISVLSIYSKSINSYYDFIYTIGKTKYNKDEIIRGTLRICKSNIIQLSNKREMNEIRQIANKFATEFS
>NC_011852.1|WP_005713493.1|331233_331452_-|hypothetical-protein
MNFEEQLVKEVVARMTEEEKWETFKALQKFDFDEMDRMFEEYDKKLRNIEQTLRKSEQLLEKMKAEHNSRKV
>NC_011852.1|WP_005712315.1|330167_330638_+|DUF4102-domain-containing-protein
MLTDSKIKSLKAKDKAYKVADRDGLYVVVSPAGTVTFRYDYRINGRRETLTIGKYGKDGISLVEAREKLMMARKMVSDGISPATEKRKKKNQIKSANNFEAFALKYIAETDFAESTRALRLATYEREIKKYFGYKLMTEISTEEIRGHCQIIGDNL
>NC_011852.1|WP_012621660.1|328461_330033_+|glutamine-hydrolyzing-GMP-synthase
MTNIHNHKILILDFGSQYTQLIARRVREIGVYCELWAWDVTEEQIREFNPTGIILSGGPESTTEENSPRAPEYVFNAGVPVLGICYGMQTMAMQLGGLTETSDHREFGYASVELKATDSLFAKLNDDLTACNPKLDVWMSHGDKVTRLPSNFQITGVTPTCPIAAMSDESRRFYGVQFHPEVTHTKSGLALLTNFVVNICGCETKWTAENIIEDAVARIKAQVGDDEVILGLSGGVDSSVTALLLHRAIGKNLHCVFVDNGLLRLNEGDQVMEMFGDKFGLNIIRVNAEDRFLDALKGIDEPEAKRKTIGKVFVDVFDDESKKLTSVKWLAQGTIYPDVIESAASKTGKAHVIKSHHNVGGLPDYMKLGLVEPLRELFKDEVRKIGLALGLPAEMLNRHPFPGPGLGVRVLGEIKKEYCDLVRRADAIFMEELHASGWYYKVSQAFTVFLPVKSVGVMGDGRKYDWAVSLRAVETIDFMTAHWAHLPYDLLGKISNRIINEVNGISRVVYDVSGKPPATIEWE
>NC_011852.1|WP_041603104.1|327061_327694_+|DUF1919-domain-containing-protein
MPLIRKITNKINDFFRKKHNAKNRQRLNTNTLTVIASNCTGAFMLHDLGLRFNSPFVNLFLTPTDFIKYVKNIAHYQTQEITFPKEIQRKYPVGLLGDIHIYFMHYHSEQEAVKKWQERTARMDLNHLFIMMAERDGCRDEDLLEFEQLPFKNKVVFTHKPYPELTSAVYIQGFEQQQKIGDLFEYCGLNRKRFYDQFDYVGWFNQHKQN
>NC_011852.1|WP_005713471.1|336628_336967_-|hypothetical-protein
MKKIDISEPFSTIKALINERQSFETCGIDAGNLFAFSQELEKYIESLNLKCRLYTKNRLAVGLSAVLNPRWGILSLAAIAAHNLLTLNPDCEIYRDLANKRVGVVWKKKFSS
>NC_011852.1|WP_005713468.1|336975_337863_-|WYL-domain-containing-protein
MQKNTVLAQRLSEILSQLNQGKRIDINQLAEDFGVSVRTIQRDIKDRLAFLEWEESGPRHYKINRYKLGILSQQDISRFALFASISDLFPKVDRDFYQEKLTDSVKVKGFQYEDIRHLDNEFQLIKQAIEAHKFIDFLYKKSGQIDGKFYKIAPYSLINKNGIWYLIGTDEDKQKTFCFTQITMLKMLDETFEPNQQLQEEIKSNDSISFGNQLSEVLVKVSSFASPYFLRRNLLPNQKLVHKSENGELILASENVNELDIVPLVQYWIPHLTIISPNGLQEKMVEKLKQYIAND
>NC_011852.1|WP_005713464.1|338080_338425_+|helix-turn-helix-transcriptional-regulator
MLDKSEQLIQTIGQAIAKYRQASGLTQAQLAEILGISNDAVSRMERGKTIPTVLRLLELSEIFHCEVADLVTESSNRSTDQAKVIEKLLQQLDSQQRSELLYLIERLVKWKNES
>NC_011852.1|WP_005713461.1|338465_339269_-|exodeoxyribonuclease-III
MKFISFNINGLRARPHQLEALIEKHQPDVIGLQEIKVADEDFPYDLVNHLGYHVFHHGQKGHYGVALLTKNQPLAVRKGFPTDNADAQKRMIMADLETPFGTLTVLNGYFPQGENRSHETKFPAKEKFYADLQRYLETELKPENPIVIMGDMNISPTDLDIGLGEVNRKRWLRDGKCSFLPEEREWLGRLHGYGLVDTFRAMNPTAEDKFSWFDYRSKGFDDNRGLRIDLVLASTPLAERCVETGIDLEIRAMDKPSDHAPVWAVFK
>NC_011852.1|WP_005713459.1|339384_340761_-|Na+/H+-antiporter-family-protein
MLLSNDVVISIIVLLALSLLRINVVIALIIAALTCGILGNSGNGMALGEALTTTVKSFTGGLGGGAETAMNYAVLGAFAVALSKSGVTDLLAYKIIKAFGKRPSGRSLFWFKYAVLFTLVAFAMASQNVIPVHIAFIPIVVPPLLSVMNQLKIDRRAVACALTFGLTATYMLIPAGFGQIFIENILVKNINQAGQPFNLVTNTAEVTQAMAIPVAGMIVGLLLAFFVTYRKPRVYVEDRPEPTADDIEARVANVKSFHIGVSIAAIVATCFVQLSTNSTVLGGLVGLIIFAVGGVFKLKQSNDIFQDGLRLMAMIGFVMIAASGYASVVNSTGGVAELVEGLKDSIGSKGMAAFLMLFVGLLITMGIGSSFSTVPIITSIYVPLCLSFGFSPLATVSIVGVAAALGDAGSPASDSTLGPTSGLNADGKHDHIWDSVVPTFIHYNIPLLVFGWIAAMIL
>NC_011852.1|WP_041603105.1|341068_342019_-|tRNA-2-thiocytidine(32)-synthetase-TtcA
MHQDAVQDTQKEKKIAYNFNKLQKRLRRNVGNAIADFNMIEDGDKVMVCLSGGKDSYTLLDILLNLRLNAPIHFDIVAVNLDQKQSGFPEHVLPEYLESIGVEYKIVEENTYGIVKEKIPEGKTTCSLCSRLRRGILYRTATELGATKIALGHHRDDMLETLFLNMFYGGKLKSMPPKLISDDGKQIVIRPLAYCKEKDIEKYAVAKQFPIIPCNLCGSQPNLQRQVVKEMLQTWDRQYPGRIETMFSALQNVAPSHLCDPNLFDFKGIKRGQLIDGVEGDIAFDKAEIPSAPVVQDKDDAADYAESGLIQIKAVS
>NC_011852.1|WP_012621663.1|342199_342766_+|UbiX-family-flavin-prenyltransferase
MLNKRIIIGISGASGFQYGYKALELLKPLDNIETHLVISKGAELTRQYETNISEEQLLSLADVVHPIHNLGASISSGSFKTIGMLIAPCSMRTLASVAHGFSDNLLARAADVVLKERRKLVLMVRETPLHLTHLDNMRKVTEMGGIIFPPVPALYHQPKTVDEIVTHSVARALDIFDLEIDIPRWTGK
>NC_011852.1|WP_041603106.1|342766_343204_+|hypothetical-protein
MKNPIPTHIVQFILKNHVVSLACHHQNQLWSASCFYAFDEKSHRLIVLSKQTTEHGKLMLANPNIAGTIAGQPDNIREIEGIQFQAVARCLENEQEKQTALQIYWKKHPLAKLMSSDVWEIVFTRIKHTENRVAFAKKSDWKKLF
>NC_011852.1|WP_049753210.1|343395_346224_+|bifunctional-[glutamate--ammonia-ligase]-adenylyl-L-tyrosine-phosphorylase/[glutamate--ammonia-ligase]-adenylyltransferase
MKLNTLMTLHQIPEHPQHFPQILPLINAIAMSDFVAQQLQKQPELLTAWLEKSPEIEDCERYAERLQAVISTVKNEEELQRELRRFRHREMATLSFIQSNQRASTQQVFERLSDLAEALILGARDWLFEQMCDEYGTPMNELGEKQELLILGMGKLGGRELNFSSDIDLIFTYPDVGETVGGRKPMENSKFFTRLGQRLIRALDEITLDGFVYRTDMRLRPFGDSGALVLSFTAMEDYYQEQGRDWERYAMIKAKILGEDLTNINHKYLKQMLRPFVYRRYLDFSAIQSLREMKQKISREVLRQGLVDNIKLGAGGIREVEFIVQTFQMMRGGRDKILQQRSLLAVLPQLAQLNLLSETQVNNLREAYLFLRHTENVLQAINDQQTQTLPTNEVDRARLAVANGAMDWESFLLQLHQHQQNVRAIFNELIGEDGSEESGEENPKFAEWRDILNVQLTQEDLATVLATYPVATQAHREIYQQLITTLQEWVKRPIGVRGREVLQKLMPKVLDQIFHEADYLLLLPRILKIVDKITLRTTYLELLLEKEQILPQLLQLCGQSIMLAEQIARYPMLLDELIFQQSLMTILPLEAYPQALREYLLRIPEDDEEALIDGLRQFKQSHLLRIAGADILGVLPVMKISDHLTYLAEAIIGEVVNLAWRQVAQRFGEPEHLQNGEKDFVVIAYGKLGGIELGYNSDLDLVFLHNAPEQSETVGGKKSISSHQFYLKLAQKINGIFNLNTSAGVLYEVDMRLRPSGEAGLLVSTFNAYNHYQKHEAWTWESQALVRTRAVYGTAELRQKFEQIRRETLSQERSSGQLREDIRNMREKMYHHLSKTTAGQFYLKTDQGGITDIEFIAQYLVLNYAHQYPQMADWSDNVRIFERAVDCGILTADEGERLKGCYTGLRDQIHRLNLLNKESIVDASEFIDERQYVATCWQRFLM
>NC_011852.1|WP_010786825.1|346240_347080_+|NADPH-dependent-7-cyano-7-deazaguanine-reductase-QueF
MNYNNECLSMLKLGKKTEYKSTYDPSLLQAVPRYLNRESLGIVKQQPFTVGADIWTLYELSWLNQNGVPQVAIADVIIDSSSSNIIESKSFKLYLNSFNQMRFPSREDVQRRIQSDLSKCAQGDVTVQIYKLSDFAMRSISEFNGECIDNQNICINRYDFTRESLQGIANGEIVEERLVSHLLKSNCLITSQPDWGSIQICYVGKQLDREKLLRYLVSFREHNEFHEQCVERIFCDLMEFAQPQKLTVYARYTRRGGLDINPFRSNFEGIPENLRMVRQ

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Crispr_ID: NC_011852_3

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_011852_3

576627-576748

Orphan

Consensus_repeat	Method
TTCATCATATGATCTTTTTTCAT	CRISPRCasFinder

2 spacers

The CRISPR arrays of NC_011852_3

>merge|NC_011852|3|576627-576748|CRISPRCasFinder
TTCATCATATGATCTTTTTTCATATCATCAGATTTCATCATTCCATCCTTTTTCATATCATCAGATTTCATCATATGATCTTTTTTCATATCATCAGATTTCATCATTCCATCCTTTTTCAT

>NC_011852|3|3|576627-576748|CRISPRCasFinder
TTCATCATATGATCTTTTTTCAT	ATCATCAGATTTCATCATTCCATCC
TTTTTCATATCATCAGATTTCAT	CATATGATCTTTTTTCATATCATCAGAT
TTCATCATTCCATCCTTTTTCAT

Protein	Signature genes	Signature genes Name	Protein_function
NC_011852.1\|WP_012621779.1\|580427_581081_+\|terminase	unknown	unknown	gnl\|CDD\|222861
NC_011852.1\|WP_010786764.1\|569194_570139_-\|50S-ribosomal-protein-L3-N(5)-glutamine-methyltransferase	unknown	unknown	gnl\|CDD\|236988
NC_011852.1\|WP_012621781.1\|582395_582914_+\|hypothetical-protein	unknown	unknown	unknown
NC_011852.1\|WP_012621776.1\|575421_576492_-\|peptide-methionine-(R)-S-oxide-reductase-MsrB	unknown	unknown	gnl\|CDD\|184456
NC_011852.1\|WP_005713976.1\|577066_577639_+\|sigma-70-family-RNA-polymerase-sigma-factor	unknown	unknown	gnl\|CDD\|237128
NC_011852.1\|WP_005714346.1\|570225_570756_+\|endonuclease-SmrB	unknown	unknown	gnl\|CDD\|235321
NC_011852.1\|WP_005713963.1\|581236_581761_+\|lysozyme	unknown	unknown	gnl\|CDD\|381620
NC_011852.1\|WP_010786762.1\|572262_573477_-\|amino-acid-permease	unknown	unknown	gnl\|CDD\|185086
NC_011852.1\|WP_005713968.1\|580224_580428_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|368296
NC_011852.1\|WP_005714341.1\|568058_569081_-\|HTH-type-transcriptional-repressor-PurR	unknown	unknown	gnl\|CDD\|236739
NC_011852.1\|WP_010786760.1\|574769_575420_-\|sulfite-exporter-TauE/SafE-family-protein	unknown	unknown	gnl\|CDD\|280792
NC_011852.1\|WP_010786754.1\|581115_581253_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|374351
NC_011852.1\|WP_005713975.1\|577635_577821_+\|zf-HC2-domain-containing-protein	unknown	unknown	gnl\|CDD\|379219
NC_011852.1\|WP_049753186.1\|578932_579229_-\|helix-turn-helix-domain-containing-protein	unknown	unknown	gnl\|CDD\|222859
NC_011852.1\|WP_005714340.1\|567451_568048_-\|DedA-family-protein	unknown	unknown	gnl\|CDD\|223659
NC_011852.1\|WP_012621780.1\|581745_582213_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|274606
NC_011852.1\|WP_012621778.1\|579396_580212_+\|GPO-family-capsid-scaffolding-protein	unknown	unknown	gnl\|CDD\|368675
NC_011852.1\|WP_010786763.1\|570897_572115_-\|tyrosine-transporter	unknown	unknown	gnl\|CDD\|273293
NC_011852.1\|WP_010786761.1\|574272_574752_-\|redoxin-family-protein	unknown	unknown	gnl\|CDD\|184456
NC_011852.1\|WP_049753185.1\|563305_566839_-\|YadA-like-family-protein	unknown	unknown	gnl\|CDD\|380308

Protein	Function_ID	Function_description	E-value
NC_011852.1\|WP_012621779.1\|580427_581081_+\|terminase	gnl\|CDD\|222861	PHA02537, M, terminase endonuclease subunit; Provisional.	2.78839e-60
NC_011852.1\|WP_010786764.1\|569194_570139_-\|50S-ribosomal-protein-L3-N(5)-glutamine-methyltransferase	gnl\|CDD\|236988	PRK11805, PRK11805, 50S ribosomal protein L3 N(5)-glutamine methyltransferase.	0
NC_011852.1\|WP_012621776.1\|575421_576492_-\|peptide-methionine-(R)-S-oxide-reductase-MsrB	gnl\|CDD\|184456	PRK14018, PRK14018, bifunctional peptide-methionine (S)-S-oxide reductase MsrA/peptide-methionine (R)-S-oxide reductase MsrB.	3.68364e-173
NC_011852.1\|WP_005713976.1\|577066_577639_+\|sigma-70-family-RNA-polymerase-sigma-factor	gnl\|CDD\|237128	PRK12530, PRK12530, RNA polymerase sigma factor; Provisional.	9.68415e-92
NC_011852.1\|WP_005714346.1\|570225_570756_+\|endonuclease-SmrB	gnl\|CDD\|235321	PRK04946, PRK04946, endonuclease SmrB.	3.83377e-101
NC_011852.1\|WP_005713963.1\|581236_581761_+\|lysozyme	gnl\|CDD\|381620	cd16901, lyz_P1, P1 lysozyme Lyz-like proteins. Enterobacteria phage P1 lysozyme Lyz is secreted to the Escherichia coli periplasm where it is membrane bound and inactive. Activation involves the release from the membrane, an intramolecular thiol-disulfide isomerization and extensive structural rearrangement of the N-terminal region. The dsDNA phages of eubacteria use endolysins or muralytic enzymes in conjunction with hollin, a small membrane protein, to degrade the peptidoglycan found in bacterial cell walls. Similarly, bacteria produce autolysins to facilitate the biosynthesis of its cell wall heteropolymer peptidoglycan and cell division. Endolysins and autolysins are found in viruses and bacteria, respectively. Both endolysin and autolysin enzymes cleave the glycosidic beta 1,4-bonds between the N-acetylmuramic acid and the N-acetylglucosamine of the peptidoglycan.	1.05525e-73
NC_011852.1\|WP_010786762.1\|572262_573477_-\|amino-acid-permease	gnl\|CDD\|185086	PRK15132, PRK15132, tyrosine transporter TyrP; Provisional.	1.49876e-136
NC_011852.1\|WP_005713968.1\|580224_580428_+\|hypothetical-protein	gnl\|CDD\|368296	pfam05125, Phage_cap_P2, Phage major capsid protein, P2 family.	0.000221902
NC_011852.1\|WP_005714341.1\|568058_569081_-\|HTH-type-transcriptional-repressor-PurR	gnl\|CDD\|236739	PRK10703, PRK10703, HTH-type transcriptional repressor PurR.	0
NC_011852.1\|WP_010786760.1\|574769_575420_-\|sulfite-exporter-TauE/SafE-family-protein	gnl\|CDD\|280792	pfam02683, DsbD, Cytochrome C biogenesis protein transmembrane region. This family consists of the transmembrane (i.e. non-catalytic) region of Cytochrome C biogenesis proteins also known as disulphide interchange proteins. These proteins posses a protein disulphide isomerase like domain that is not found within the aligned region of this family.	8.22254e-54
NC_011852.1\|WP_010786754.1\|581115_581253_+\|hypothetical-protein	gnl\|CDD\|374351	pfam16080, Phage_holin_2_3, Bacteriophage holin family HP1. Phage_holin_2_3 is a family of small hydrophobic phage proteins called holins with one transmembrane domain. Holins are produced by double-stranded DNA bacteriophages that use an endolysin-holin strategy to achieve lysis of their hosts. The endolysins are peptidoglycan-degrading enzymes that are usually accumulated in the cytosol until access to the cell wall substrate is provided by the holin membrane lesion.	2.72766e-08
NC_011852.1\|WP_005713975.1\|577635_577821_+\|zf-HC2-domain-containing-protein	gnl\|CDD\|379219	pfam13490, zf-HC2, Putative zinc-finger. This is a putative zinc-finger found in some anti-sigma factor proteins.	0.00822014
NC_011852.1\|WP_049753186.1\|578932_579229_-\|helix-turn-helix-domain-containing-protein	gnl\|CDD\|222859	PHA02535, P, terminase ATPase subunit; Provisional.	1.84404e-24
NC_011852.1\|WP_005714340.1\|567451_568048_-\|DedA-family-protein	gnl\|CDD\|223659	COG0586, DedA, Uncharacterized membrane-associated protein [Function unknown].	1.31235e-39
NC_011852.1\|WP_012621780.1\|581745_582213_+\|hypothetical-protein	gnl\|CDD\|274606	TIGR03495, Probable_spanin_inner_membrane_subunit, phage lysis regulatory protein, LysB family. Members of this protein family are phage lysis regulatory protein, including the well-studied protein LysB (lysis protein B) of Enterobacteria phage P2. For members of this family, genes are found in phage or in prophage regions of bacterial genomes, typically near a phage lysozyme or phage holin.	0.000477867
NC_011852.1\|WP_012621778.1\|579396_580212_+\|GPO-family-capsid-scaffolding-protein	gnl\|CDD\|368675	pfam05929, Phage_GPO, Phage capsid scaffolding protein (GPO) serine peptidase. This family consists of several bacteriophage capsid scaffolding proteins (GPO) and some related bacterial sequences. GPO is thought to function in both the assembly of proheads and the cleavage of GPN. The family is found to function as a serine peptidase, with a conserved Asp, His and Ser catalytic triad, as in subtilisin, and as represented in MEROPS:S73. The family includes capsid assembly scaffolding protein from Enterobacteria phage P2 which cleaves itself and then becomes the scaffold protein upon which the bacteriophage prohead is built - a mechanism quite common amongst phages.	3.6275e-111
NC_011852.1\|WP_010786763.1\|570897_572115_-\|tyrosine-transporter	gnl\|CDD\|273293	TIGR00837, Tyrosine-specific_transport_protein, aromatic amino acid transport protein. The Hydroxy/Aromatic Amino Acid Permease (HAAAP) Family- tyrosine/tryptophan subfamily (TC 2.A.42.1) The HAAAP family includes well characterized aromatic amino acid:H+ symport permeases and hydroxy amino acid permeases. This subfamily is specific for aromatic amino acid transporters and includes the tyrosine permease, TyrP, of E. coli, and the tryptophan transporters TnaB and Mtr of E. coli. [Transport and binding proteins, Amino acids, peptides and amines].	1.26385e-125
NC_011852.1\|WP_010786761.1\|574272_574752_-\|redoxin-family-protein	gnl\|CDD\|184456	PRK14018, PRK14018, bifunctional peptide-methionine (S)-S-oxide reductase MsrA/peptide-methionine (R)-S-oxide reductase MsrB.	2.36279e-34
NC_011852.1\|WP_049753185.1\|563305_566839_-\|YadA-like-family-protein	gnl\|CDD\|380308	NF033477, EmaA_autotrans, collagen-binding adhesin autotransporter EmaA. EmaA (extracellular matrix protein adhesin ) is an outer membrane protein first described in Aggregatibacter (Actinobacillus) actinomycetemcomitans, a member of the Gammaproteobacteria. It is a glycoprotein, and has a C-terminal beta-barrel domain that marks it as an autotransporter. It serves as an adhesin that binds collagen, the most abundant material in the host extracellular matrix. It shares homology with the collagen-binding protein YadA of Yersinia enterocolitica.	8.68684e-25

>NC_011852.1|WP_012621776.1|575421_576492_-|peptide-methionine-(R)-S-oxide-reductase-MsrB
MKSHKTVLFTLIMSAISNNSLAINHTNNSSKEMSKMTQTQNENIREIYLAGGCFWGIEAYMERIYGVKNATSGYANGKTDKTHYHIIGKTDHAETVHITYDANKISLEKLLKYYFQVIDPTSLNKQGNDRGRQYRTGIYYQNEQDKAIILKEIEALQTKYKDKIQVEVEPLKHYILAEEYHQDYLKKNPNGYCHIDLEQANNIIIDPKDYPKPSDEELKAKLTPLQYSVTQKKNTERSFSNEYWDNKKDGLYVDITTGEPLFSSRDKYDSGCGWPSFTKPIDKNVVTYQKDTSFNMIRTEVLSRSGKAHLGHVFDDGPKDKGGLRYCINSAAIKFIPLEQMEKENYGYLINLIKGK
>NC_011852.1|WP_010786760.1|574769_575420_-|sulfite-exporter-TauE/SafE-family-protein
MFDQNLLISSVFLAGLASFLSPCIFPIVPIYFGILSKGGKKVLNTLLFIMGLSLTFVSLGFSFGFLGDLLLNDTTRVIAGIIVIILGIHQLGIIKINFLEQTKLVEIKTNGKSASVEAFVLGLTFSLGWTPCIGPILASVLALSGDEGSALYGGAMMFVYVLGLALPFIIFSFFSDELLKRAKSLNKHLDKFKIIGGILIILMGLLLITNNLHSFM
>NC_011852.1|WP_010786761.1|574272_574752_-|redoxin-family-protein
MKKIMGLLLMLFSFNAFAEENKNLADIQFKDLDNNIVSLEKYKGKNVYVKMWASWCPICLAGLAEIDDLSADQNKNFEVITIVSPDKKGEKSTEKFIEWYKGLDYKNVVVLLDEQGEVLKRAKVRGYPSNVFLDSELNVKKVVPGHLSTTQITESINSK
>NC_011852.1|WP_010786762.1|572262_573477_-|amino-acid-permease
MKNKTLGSTLIVAGTTIGAGMLAMPLTSAGIGFGFTFLLLVALWLLLCFSALLFVEVYQTVDSDAGLGTLAEKYYGPFGRIVSTTVLIVFLYAILSAYVSGGSSILAAFLPTIIDAETTTRISGVIFTVVFGIFIILGTTSVDAVNRLLFTTKILAFILVLFLLLPKVSIDNLMAMPIDNALLISASPIFFTAFGFHGSIPSLNKYLEGNVKALRISIVVGTSIPLVAYILWQLATHGVLTQTEFLQILEKDPTLNGLAEAARQITGSSIIGAMVRIFSVLALITSFLGVALGLFEALEDLLKRVNINAGRVSLGALTFIPPMLFAFFYPQGFIAALGYAGQMFAFYAIVLPIAMVWKLRRQNLNLPYQVKGGSISLLLALVIGVFIVMVPFLIESGWLPKVVG
>NC_011852.1|WP_010786763.1|570897_572115_-|tyrosine-transporter
MKNKILGSALMIAGTTIGAGMLAMPLTSAGMGFGMTLVLLVGLWLLLTYTGLLFMEVYQTAAQQDVGVATLAEQYFGMPGRVLATVSLLVLLYALLAAYITGGGSLVSGLLPEMGEGDTTLKVGILLFTFILGAFVVVGIKGVDGLTRVLFIGKIVAFVFVLLMMFPKAKLENLTAVPLDNLLVISAIPIFFTSYGFHVIMGSINSYLDADIRKIRIAVIIGTVIPLGAYLLWQLATHGVLSQGEFVTLLNQDPTLNGLVKATSQITGSTILGEMVRIFSALALITSFLGGAMGIFEGVGDLLKRVNLPANRAILTPLTFIPPLAFALFYPNGFIAALGYAGLLFAFYGLILPIGLVWKARQAHPNLPYRVAGGSIGLILAFIMGIVIIVIPFLMQNGILPTVAG
>NC_011852.1|WP_005714346.1|570225_570756_+|endonuclease-SmrB
MLENDELALFREAIKGTKKIKQDTFVPKVEPRKKINEIRELKEKADTLFYFSDEYEPLLTEENDKVKYRREDVDPYILKQLRRGDFHPELFLDLHGLTKENAKKELASLILACEREGIYCASIMTGYGTRALKYQIPRWLVQHPKVIALHQAPREWGGNSAILILIEQPEKLDKKR
>NC_011852.1|WP_010786764.1|569194_570139_-|50S-ribosomal-protein-L3-N(5)-glutamine-methyltransferase
MYEHNLELLDEIASSPVADDLATILDMMRWAYSYFNASDLYYGHGHDNAWDEANQLVLTALALPMDVPETLYASRLTRVEKERIVEMVEQRLGLRKPVAYLTNSAWFSGLEFYVDERVIVPRSPIGELIQQGFTGILRAEPKRILDMCTGSGCIAIACADKFPNAEIDAVDLSVDALNVAEINIERHNMAHRVFPFQSDLFDDLPQDRYDLIVTNPPYVDQEDLDDMPEEFHHEPEMALGSGADGLDITKRILAQAADFLSDNGVLVCEVGNSMVHLIEQFPSVPFHWLEFKNGGLGVFSLTREQLVANRHLFF
>NC_011852.1|WP_005714341.1|568058_569081_-|HTH-type-transcriptional-repressor-PurR
MATIKDVAKLVGVSTTTVSHVINKTRFVAEDTTKAVWEAIASLNYSPSAVARSLKVNTTKSIGMIITTSEAPYFAEIVLAVEEYCYRQGYSLFLCNTQNDAEKVQNHLDMLIKKRVDGILVMCSEYTENSLALFNGTNVPMVVMDWGPNDGKSDRIIDHCLDGGYMATKHLIDNGHRDIAIIAGYLYKTTAKARYDGFVKAMTEAGLLIRKEWIFENDFQPEGGYESMNNLLNQDKLPTAVICGCDAMALGVISAITEKGLSVPQDISVIGYDNIHSSRFYAPPLTTIHQSKTRLGQMAIDTLLERIQQHNEQPSEPVTPKVLEFYPELVVRSSVRNLNQ
>NC_011852.1|WP_005714340.1|567451_568048_-|DedA-family-protein
MELLIEFFSSYGYWAVFLVLLACGFGLPIPEDITLVSGGVISGLGYTNVHWMLFVSMLGVLVGDSTMYWLGRIYGEKILQFPLIRRIATPERFATVQERFEKQGWKLLFVARFLPGLRAVVYLVSGITRRVTFTRFVLVDFFAAIISVPIWVYLGDFGAKNLDWLHQQIQKGQMAIWLMLLIGVAIVFWKWKKSHKVN
>NC_011852.1|WP_049753185.1|563305_566839_-|YadA-like-family-protein
MNKIFRVIWSHAQQAWVVVSELVKSHTKTSACTDKRAQVCTSDYFLDKQQDKFKLSFLSLVLLSIFFSPSAAANATNNAQPYLQDGATKSDKGYDDGTIGIGKESKASYGAIAIGQKAQAEARHNIAIGYGADSGTDANSITIGYNTKVTGQEAIAIGKQSKAGGRSVVLGGQAKGTSTQTVAIGNLATASASQSIAIGARSSSTAEYGIAVGGGATAGKHAVALGRESKGAGTDSIAIGNSAKTTGPDSVVVGANINVTDGQLVAIGYQASAKSRSTALGYKASAGGKHSVAVGDNAVTNDGAARATALGNNTVVSVGGGVALGYGSNANTAGGVEGLKQAHSVTTGESTVANGFKSTEKVDGNNKIGAVSVGNDRIKRQIVNVAAGKQDTDAVNVAQLKSLTMQTGGDNNSSGKVGIWDGKLEVKGTNEEIKTKAEGSTITISLEDKIKEQLAEIANKMSSFKIKTDKDNNEATIKDGDTIQFTGGENIKITRDNKNLTFGVTSGMFSSTTDGKLSKQTAGLATVDAVVSAVNSAGWKLTIAKGAGQATHLNTPYLIKMGDTVKFTAGDNIKLTQENGNITIATKGKLIENVVNETNGDVKITYTDGSHSTIKKGEKGDRGETGPAGPPGPMGPAGPKGDAGPRGEAGSTGPMGPVGPKGEKGDQGLVGPAGPAGERGEQGPKGDRGPKGDTGERGATGPAGPAGAKGEQGQKGDTGPMGPAGPTGAQGPVGPRGEAGPAGATGPQGPKGDNGAPGARGEKGEPGPAGPTGPRGDRGETGPAGPAGPRGEQGPKGEQGIQGPAGPTGPQGPQGTAGIQGPKGERGNVSVSGLPMEYTTEDGKSIINMGGNFYLEEPAKDGSIKLIPVVNVKGKFSTKTQNPDGSITLKSLAVKVNLANETPMVLGNVAEGVADTDAVNVKQLKSAKTEVESTDHSVVIKERQGDNQQIVYDLAVAKTKLTASKDKRTISAADKGNHFATGDEVAVAINTATAAARTEVEAGKNVKVTSKTGANGQNIYNVSVSGDLSDITSISNGDTKVSLGKDKQGNPVVNMNGARITNVGDGSAEGDIVNVRQLNKVVSSVNTGFNQLSRDIGRVDVNARAGIASAVAMANLPQISLPGKSAISVSNAQYRGQSAYAIGYSKISDNGKWLIRASVGSNTQRDTTIGGGVGFVW
>NC_011852.1|WP_005713976.1|577066_577639_+|sigma-70-family-RNA-polymerase-sigma-factor
MILKEINSSQMAAIREQMLKFAHLQLRDSQLAEDMVQEALLNALKNLDSFKRDAAFKTWVFAILKNKIIDYLRQKDRLVLESDLRDDENDSNVFFDQDGYWREECYPQEWQQPENAVYSDEFWIIFELCLTKLPAKQAHVFMMREYLELSANEICHTAEISQANLHTLLYRSRLQLQQCLSSKSIFGGKK
>NC_011852.1|WP_005713975.1|577635_577821_+|zf-HC2-domain-containing-protein
MKCQEVTKLVSEAQERPLLLKEKIGVRIHLLYCPHCRKFEKHCQQMSQLMKKFADDQNNAD
>NC_011852.1|WP_049753186.1|578932_579229_-|helix-turn-helix-domain-containing-protein
MTDIATNQAEKTALINMNTHREAQLKYWAGYSLTEIAKMLNIPVSTIASWKKREKWDEAPLFERVSGNIENRYMLLLQKDVKTGYDFKELDFLMQRRE
>NC_011852.1|WP_012621778.1|579396_580212_+|GPO-family-capsid-scaffolding-protein
MSKKSNWFVVATEGATVDGRQIERQWLSDIAETYDPKTYGARINLEHFHMSWFDPELAHSKCYGDVLAVKAEENDEGKLQLYAQIEPTDELVELVNSKQKVYTSIEVRTNFAKTGKAYLTGLAVTDTPASLGTQYLSFTTKNGEQQGEIFTTEAVECSLTFAEEPVSFFEKMKAMFSKEKADTAQHKADVEARFAEHEQAQLLLAEKFTELEDKLKQTEAEKMALCADFEKLSADLTALQSRVDVIGSEPEHGYTPRPEITGGELNNERVF
>NC_011852.1|WP_005713968.1|580224_580428_+|hypothetical-protein
MRKETATKFNTYLAGVAQDNGVDYNHIFTGKNFVSSNDDFVVENYAQVALLKNISMLASPDTTGVGG
>NC_011852.1|WP_012621779.1|580427_581081_+|terminase
MRPTQAHYLRVTAELAQSSEQAQLENLDEYEKMLYLLARHKKDLKAIASMEQRASYKKSILHHYLPWIEGALSAGNGKQDNVLMTWQVWSVDCGEYHLALQIADYAIHQDLTLPDGFSRSLCSMLAEEFADAAKKAQKVQKPFEVSYLLRVDELTKEKDMPDESRARLYREIGLLLETTQPETALSYLERALELNLNIGVQGSVKKLQKQLNQADTD
>NC_011852.1|WP_010786754.1|581115_581253_+|hypothetical-protein
MGILFGLFTLLMNWYYKDREIKLKEKALERYKINLKDILDDEQKS
>NC_011852.1|WP_005713963.1|581236_581761_+|lysozyme
MNKNLKFGGAMVCGIGAIIGLVQLNHPEIRTSPKGLDIIGNTEGCRRDPYVCPANVLTVGIGSTEATSGKIERKIYSDKEIADRWAKDLAEAERCVNRYANGKKMPQGAFDALTSITFNAGCGTMRHSTLFKLANQGYSPAMCEQFSRWVYANGKKLRGLEIRREKEQALCLAL
>NC_011852.1|WP_012621780.1|581745_582213_+|hypothetical-protein
MFSIISGMIEKSFGKAMIIALLIGVCINAFLCYERKTLQADNQSKQEEIALVRADNQSLANQLEQANQHILQYQKQVDKLHQQVLTKLTQAEKRTNEILLELENNQSWSYQPVPTGVSRLLNQRSDTVSNSKANSAPLPPNKAVPQPQVRDKNQR
>NC_011852.1|WP_012621781.1|582395_582914_+|hypothetical-protein
MLSYHFTKTQDNDSGIIYISTEFQIVNVTYMAIFSDDKDTLLFLEQDPTIAEIIQHKKTHSIKFAVKEYIETGNEDLYASPLNHQFGKTEIKALKSHLEKLVYEHYLLFKPDCYVFVADRPSLARMYSKMCCNPSSFMSDFETVSNLGDQQDCFIIKTPTYTGGNNEKNDRR

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Click the colored protein region to show detailed information

Crispr_ID: NC_011852_4

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_011852_4

593800-593898

Orphan

Consensus_repeat	Method
AATGGCGGTTTTGCTTCTTCCCGAATGTCG	CRISPRCasFinder

1 spacers

The CRISPR arrays of NC_011852_4

>merge|NC_011852|4|593800-593898|CRISPRCasFinder
AATGGCGGTTTTGCTTCTTCCCGAATGTCGCTTTCCGCCATTGGGGAATGTTCATTAGTGGCATTGGGTAATGGCGGTTTTGCTTCTTCCCGAATGTCG

>NC_011852|4|4|593800-593898|CRISPRCasFinder
AATGGCGGTTTTGCTTCTTCCCGAATGTCG	CTTTCCGCCATTGGGGAATGTTCATTAGTGGCATTGGGT
AATGGCGGTTTTGCTTCTTCCCGAATGTCG

Protein	Signature genes	Signature genes Name	Protein_function
NC_011852.1\|WP_012621787.1\|590264_590450_+\|type-II-toxin-antitoxin-system-HicA-family-toxin	unknown	unknown	gnl\|CDD\|377942
NC_011852.1\|WP_012621802.1\|599130_599301_-\|DUF1508-domain-containing-protein	unknown	unknown	gnl\|CDD\|377831
NC_011852.1\|WP_041603123.1\|598293_598539_+\|hypothetical-protein	unknown	unknown	unknown
NC_011852.1\|WP_012621791.1\|592710_593382_-\|holin	unknown	unknown	gnl\|CDD\|369163
NC_011852.1\|WP_012621789.1\|591312_591882_-\|recombination-protein-NinG	unknown	unknown	gnl\|CDD\|368603
NC_011852.1\|WP_012621797.1\|596725_597202_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|274008
NC_011852.1\|WP_012621788.1\|590938_591316_-\|antitermination-protein	unknown	unknown	unknown
NC_011852.1\|WP_010786745.1\|588084_588507_+\|type-II-toxin-antitoxin-system-YafO-family-toxin	unknown	unknown	gnl\|CDD\|372840
NC_011852.1\|WP_041603122.1\|595612_596266_+\|helix-turn-helix-domain-containing-protein	unknown	unknown	gnl\|CDD\|224885
NC_011852.1\|WP_012621798.1\|597319_597502_+\|type-II-toxin-antitoxin-system-HicA-family-toxin	unknown	unknown	gnl\|CDD\|377942
NC_011852.1\|WP_012621794.1\|595270_595477_-\|helix-turn-helix-transcriptional-regulator	unknown	unknown	gnl\|CDD\|197775
NC_011852.1\|WP_012621793.1\|594208_594991_-\|Rha-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|378235
NC_011852.1\|WP_012621796.1\|596298_596733_+\|hypothetical-protein	unknown	unknown	unknown
NC_011852.1\|WP_005714900.1\|590479_590917_+\|type-II-toxin-antitoxin-system-HicB-family-antitoxin	unknown	unknown	gnl\|CDD\|374224
NC_011852.1\|WP_010786746.1\|587549_588092_+\|hypothetical-protein	unknown	unknown	unknown
NC_011852.1\|WP_173655637.1\|589603_590041_+\|hypothetical-protein	unknown	unknown	unknown
NC_011852.1\|WP_012621799.1\|597541_597961_+\|type-II-toxin-antitoxin-system-HicB-family-antitoxin	unknown	unknown	gnl\|CDD\|224514
NC_011852.1\|WP_071610285.1\|592490_592688_-\|hypothetical-protein	unknown	unknown	unknown
NC_011852.1\|WP_012621801.1\|598816_599104_+\|hypothetical-protein	unknown	unknown	unknown
NC_011852.1\|WP_041603231.1\|592026_592455_-\|recombination-protein-NinB	unknown	unknown	gnl\|CDD\|368607

Protein	Function_ID	Function_description	E-value
NC_011852.1\|WP_012621787.1\|590264_590450_+\|type-II-toxin-antitoxin-system-HicA-family-toxin	gnl\|CDD\|377942	pfam07927, HicA_toxin, HicA toxin of bacterial toxin-antitoxin,. HicA_toxin is a bacterial family of toxins that act as mRNA interferases. The antitoxin that neutralizes this is family HicB, pfam15919.	1.3405e-11
NC_011852.1\|WP_012621793.1\|594208_594991_-\|Rha-family-transcriptional-regulator	gnl\|CDD\|378235	pfam09669, Phage_pRha, Phage regulatory protein Rha (Phage_pRha). Members of this protein family are found in temperate phage and bacterial prophage regions. Members include the product of the rha gene of the lambdoid phage phi-80, a late operon gene. The presence of this gene interferes with infection of bacterial strains that lack integration host factor (IHF), which regulates the rha gene. It is suggested that Rha is a phage regulatory protein.	1.16763e-13
NC_011852.1\|WP_012621789.1\|591312_591882_-\|recombination-protein-NinG	gnl\|CDD\|368603	pfam05766, NinG, Bacteriophage Lambda NinG protein. NinG or Rap is involved in recombination. Rap (recombination adept with plasmid) increases lambda-by-plasmid recombination catalyzed by Escherichia coli's RecBCD pathway.	1.75449e-79
NC_011852.1\|WP_012621797.1\|596725_597202_+\|hypothetical-protein	gnl\|CDD\|274008	TIGR02168, Chromosome_partition_protein_Smc, chromosome segregation protein SMC, common bacterial type. SMC (structural maintenance of chromosomes) proteins bind DNA and act in organizing and segregating chromosomes for partition. SMC proteins are found in bacteria, archaea, and eukaryotes. This family represents the SMC protein of most bacteria. The smc gene is often associated with scpB (TIGR00281) and scpA genes, where scp stands for segregation and condensation protein. SMC was shown (in Caulobacter crescentus) to be induced early in S phase but present and bound to DNA throughout the cell cycle. [Cellular processes, Cell division, DNA metabolism, Chromosome-associated proteins].	0.00419126
NC_011852.1\|WP_010786745.1\|588084_588507_+\|type-II-toxin-antitoxin-system-YafO-family-toxin	gnl\|CDD\|372840	pfam13957, YafO_toxin, Toxin YafO, type II toxin-antitoxin system. YafO is a toxin which inhibits protein synthesis. It acts as a ribosome-dependent mRNA interferase. It forms part of a type II toxin-antitoxin system, where the YafN protein acts as an antitoxin. This domain forms complexes with yafN antitoxins containing pfam02604.	4.91552e-33
NC_011852.1\|WP_041603122.1\|595612_596266_+\|helix-turn-helix-domain-containing-protein	gnl\|CDD\|224885	COG1974, LexA, SOS-response transcriptional repressors (RecA-mediated autopeptidases) [Transcription / Signal transduction mechanisms].	2.46544e-23
NC_011852.1\|WP_012621798.1\|597319_597502_+\|type-II-toxin-antitoxin-system-HicA-family-toxin	gnl\|CDD\|377942	pfam07927, HicA_toxin, HicA toxin of bacterial toxin-antitoxin,. HicA_toxin is a bacterial family of toxins that act as mRNA interferases. The antitoxin that neutralizes this is family HicB, pfam15919.	8.08351e-09
NC_011852.1\|WP_012621794.1\|595270_595477_-\|helix-turn-helix-transcriptional-regulator	gnl\|CDD\|197775	smart00530, HTH_XRE, Helix-turn-helix XRE-family like proteins.	9.47824e-13
NC_011852.1\|WP_041603231.1\|592026_592455_-\|recombination-protein-NinB	gnl\|CDD\|368607	pfam05772, NinB, NinB protein. The ninR region of phage lambda contains two recombination genes, orf (ninB) and rap (ninG), that have roles when the RecF and RecBCD recombination pathways of E. coli, respectively, operate on phage lambda. NinB binds to single-stranded DNA.	7.43928e-64
NC_011852.1\|WP_005714900.1\|590479_590917_+\|type-II-toxin-antitoxin-system-HicB-family-antitoxin	gnl\|CDD\|374224	pfam15919, HicB_lk_antitox, HicB_like antitoxin of bacterial toxin-antitoxin system. This is a family of HicB-like antitoxins.	2.4347e-24
NC_011852.1\|WP_012621802.1\|599130_599301_-\|DUF1508-domain-containing-protein	gnl\|CDD\|377831	pfam07411, DUF1508, Domain of unknown function (DUF1508). This family represents a series of bacterial domains of unknown function of around 50 residues in length. Members of this family are often found as tandem repeats and in some cases represent the whole protein. All member proteins are described as being hypothetical.	5.94265e-19
NC_011852.1\|WP_012621799.1\|597541_597961_+\|type-II-toxin-antitoxin-system-HicB-family-antitoxin	gnl\|CDD\|224514	COG1598, COG1598, Predicted nuclease of the RNAse H fold, HicB family [General function prediction only].	1.39026e-13
NC_011852.1\|WP_012621791.1\|592710_593382_-\|holin	gnl\|CDD\|369163	pfam06992, Phage_lambda_P, Replication protein P. This family consists of several Bacteriophage lambda replication protein P like proteins. The bacteriophage lambda P protein promoters replication of the phage chromosome by recruiting a key component of the cellular replication machinery to the viral origin. Specifically, P protein delivers one or more molecules of Escherichia coli DnaB helicase to a nucleoprotein structure formed by the lambda O initiator at the lambda replication origin.	1.5041e-76

>NC_011852.1|WP_012621791.1|592710_593382_-|holin
MQNVASMNLKSLVGQEPNYQVPAKTTAIPDGAIRAVNQLFIQLRAIFPAWKNSFPDADSYREAKRIWLETLVNEKITTIEQLQNGIERAKKSKNPFWPSVGEFVEWCKTVDYEALGLPDEDKLYKRLQAFMAFGMEEIQKFKFVSTAEYYLITGLYVRNRAGEWSDKQLKDEIKKSLVKMSKRLKTGEVLPEPKLALPQEVKAVNSEKVRAFWGGLLKQVRGF
>NC_011852.1|WP_071610285.1|592490_592688_-|hypothetical-protein
MSDYKCPKCGGELEDLSINDDWGWHVEEPYRCNGHYTGRFPNISKDCAMNRTKSCGYFTKEQVKK
>NC_011852.1|WP_041603231.1|592026_592455_-|recombination-protein-NinB
MEYKQKYFLRTEQIKNNALEFVKALPIDEKKPLVVDVKPATRNLKQNAKFHAMCVDIARQVQFNGEWLPLEAWKVLLISAHAEATKEGSCLVTGLEGELVNIRESTAQMSVKRMASLIEYATSWGVSNGVHFNDRWNFWGVK
>NC_011852.1|WP_012621789.1|591312_591882_-|recombination-protein-NinG
MIKPKVKTRKCKCCGGEFKSADSFRKWCSAECGVKLAKIAQEKARQKAIEKRNREERAKIKATRERLKSRSEWLKDAQAVFNEYIRLRDKDEPCISCQRFHQGQYHAGHYRTVKAMPELRFNEDNVHKQCSACNNHLSGNITEYRINLVRKIGVERVEALESYHPPVKWSAEDCKEIIKTYRAKIKELK
>NC_011852.1|WP_012621788.1|590938_591316_-|antitermination-protein
MIRLHISIDDILNVWVRRWASHRGCRGYPSLQSFMPEATVKITKYSIDELSEEHYLKLDEAVMTLHDLNLEAYQVLMAVFLQGQDKKNICLEMHISPRTYDNRLRTARDFMEGAVFGSGLIRLKF
>NC_011852.1|WP_005714900.1|590479_590917_+|type-II-toxin-antitoxin-system-HicB-family-antitoxin
MLFTVGVETPHNENEAFGLCVPALFTDEYSCFSAADAIDEIIPNVKDAIHTMLEMMVEDEFDISTLQDKGFVHYKQQEDFSHCDSWLLVDIDISAFLGKKQRVNIVLPQYLLDRIDNRVSHSNFYRDRSHFLAVASQRELTAQQV
>NC_011852.1|WP_012621787.1|590264_590450_+|type-II-toxin-antitoxin-system-HicA-family-toxin
MHSSDLIKELKEVGCFFVRHGKGDHQIWQSPITGKRFPIPHPKQDLPVGTSRSIKKSAGLL
>NC_011852.1|WP_173655637.1|589603_590041_+|hypothetical-protein
MGVYTEFGIGSLLTDLNKPNTPFITLGCAYWLFKDNRELSRSYLEFTFKNINVANNLTFLQQIDEEFEKYLSTHKNELSQIYSVPPEAFNLVVQNYYWQMDKFSYFGSEERSLIYVEMASQRHSDIEIFLELLHRFLTEYLVVPS
>NC_011852.1|WP_010786745.1|588084_588507_+|type-II-toxin-antitoxin-system-YafO-family-toxin
MAKVFVHPRLTLLEPLRPLAEGLLTFEASYRQIYPSTIGNYGRFEENPRSLLAGIHKLHVAVSEADFTKWQGKAGQSRKSDNYLVYAKHDFEDDVYLILDFISPDAHQRIKSVLADLVLIAEEFQETFPERFPEKYQQLI
>NC_011852.1|WP_010786746.1|587549_588092_+|hypothetical-protein
MKKSFTEKAKSLKDVSLAMGIFTSFFSQEIEAYPKQSDVLQVINQVKKASTLLTQQSESQTELFFAGLKELTQGVSLLNAVVRSMKTPEKVIDDLIFIDLMLNKLVKDIRQNYYHHFQEQLNDRATFKDYMNEVASFNLFTITLRQELGHYMVVPSTSNFTQADLDELIADSNRRYGING
>NC_011852.1|WP_012621793.1|594208_594991_-|Rha-family-transcriptional-regulator
MLLANKNPRCNVGNGEIMFMKTELLSLNQKENATLTMSSREIARITESRHRDVCLSIRNLMNKGVIGGYAESPYTHEQNGQVYYEYHINKRDTYVIVAQFSPEFTARLVDRWQELEQKQVQQLPSYSEALRQLADKIEESEQKSLQIASMESYFRNGISPFEFVKGLNGVNALKIGAFLVDKNWLYQDGNHKRVKSYARDQYLTEETTEISQHGKDPFVAYKPVLLKKGAAKLYEWYTKRELPMKANWNGVFTQDKVVGL
>NC_011852.1|WP_012621794.1|595270_595477_-|helix-turn-helix-transcriptional-regulator
MNRISEFRKAANLTQVEIAKLINKTQGAFGHYETGLREPSLSTAKKIVRVLNEHGVACSLDDVFPVGS
>NC_011852.1|WP_041603122.1|595612_596266_+|helix-turn-helix-domain-containing-protein
MKKQWNQYVREKMQEQNLRQDDIAESMGKTQGAIGHWLTGRRMPNVNEVAQMINLTGVNKVILNGDGTIEDFDPNITPTSVKKSRAYPLVSSIQAGMWTETYDFRDSEGYDYIDTEIDAGPDAFFLRVSGMSMEPKFSEGDLVLIDIRKRPHPGDFVAAVNGNGEATLKRYRELGELSPSGNPHFELVPLNQDFPTLSSMKQDIRIIGVAVEHRSYL
>NC_011852.1|WP_012621796.1|596298_596733_+|hypothetical-protein
MKDIEIMKKVTPEILANYLNTKGASLETFRCPICGRDHITIIDNQPFESSGSKVEISGVGTAVMQTILPTVLYPRHSEFNHLIENGLIDSSFHYLGNLITHMSANNSVILPVIHMICDNCGNIRTFSKAKILEWIAQQEGEKNE
>NC_011852.1|WP_012621797.1|596725_597202_+|hypothetical-protein
MNNLITPRVNNTISATMINQQPINQMEIIMQDYTFRVSSLEDKVNSIEKDVNTIKSNYLTKGEFFKVGGIALISLIITAGSALWVVFTNLDSKIGSWADKNEQRFQQIESKMHVLDVRLTKVEIKIDELDKKLGVIDNKFDNLTDKIDTLIQQKQVKN
>NC_011852.1|WP_012621798.1|597319_597502_+|type-II-toxin-antitoxin-system-HicA-family-toxin
MKYSEFLRYLLAQGCEIETQKRGSHRKVTLNGKQSVFPYHGSKEIGTGLVNKIKKDLDLK
>NC_011852.1|WP_012621799.1|597541_597961_+|type-II-toxin-antitoxin-system-HicB-family-antitoxin
MLRYPVEITKDDNNTYLVTCPDIPEMASVGEDIEEALLEAKDGLAAALEFYFDDRRTIPLPSSAKEGQHTVDLSILQSMKVFLLNEMIKQDVRKAEMARRLDVHLPQIDRLLDFKHATKVEFVEKAYSKLNRHFTILPH
>NC_011852.1|WP_041603123.1|598293_598539_+|hypothetical-protein
MTEQVSLFYSKQFKHVKTYDNSAVTGKAYSMFVDVDLNIVIEVWESRWIAEEKQWNLLSIKKSELMSADEGKKFWKEMINL
>NC_011852.1|WP_012621801.1|598816_599104_+|hypothetical-protein
MTKIIIERNPTSNKYCEKAEVRTTGKAGRLARMFAKNRKKQTANTLSRVDIACLERPSKKMIDIANYACNKGKIKPTTVRAKEKIRRSCRELIRI
>NC_011852.1|WP_012621802.1|599130_599301_-|DUF1508-domain-containing-protein
MYFQIFQGVNGQWYWRLKSANHETIASSEGYTTKQNCLHCIGLVMDTMRKTPVYEV

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Click the colored protein region to show detailed information

Crispr_ID: NC_011852_5

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_011852_5

638392-638490

Orphan

Consensus_repeat	Method
AATGGCGGTTTTGCTTCTTCCCGAATGTCG	CRISPRCasFinder

1 spacers

The CRISPR arrays of NC_011852_5

>merge|NC_011852|5|638392-638490|CRISPRCasFinder
AATGGCGGTTTTGCTTCTTCCCGAATGTCGCTTTCCGCCATTGGGGAATGTTCATTAGTGGCATTGGGTAATGGCGGTTTTGCTTCTTCCCGAATGTCG

>NC_011852|5|5|638392-638490|CRISPRCasFinder
AATGGCGGTTTTGCTTCTTCCCGAATGTCG	CTTTCCGCCATTGGGGAATGTTCATTAGTGGCATTGGGT
AATGGCGGTTTTGCTTCTTCCCGAATGTCG

Protein	Signature genes	Signature genes Name	Protein_function
NC_011852.1\|WP_010786732.1\|639862_640063_-\|helix-turn-helix-domain-containing-protein	unknown	unknown	gnl\|CDD\|374243
NC_011852.1\|WP_012621838.1\|638800_639583_-\|Rha-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|378235
NC_011852.1\|WP_012621789.1\|635904_636474_-\|recombination-protein-NinG	unknown	unknown	gnl\|CDD\|368603
NC_011852.1\|WP_005714534.1\|640941_641790_+\|KilA-N-domain-containing-protein	unknown	unknown	gnl\|CDD\|367917
NC_011852.1\|WP_012621839.1\|645881_646103_+\|hypothetical-protein	unknown	unknown	unknown
NC_011852.1\|WP_071610285.1\|637082_637280_-\|hypothetical-protein	unknown	unknown	unknown
NC_011852.1\|WP_012621837.1\|635303_635522_+\|hypothetical-protein	unknown	unknown	unknown
NC_011852.1\|WP_005714781.1\|634830_635007_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|224705
NC_011852.1\|WP_012621835.1\|633975_634539_+\|hypothetical-protein	unknown	unknown	unknown
NC_011852.1\|WP_010786728.1\|645696_645867_-\|DUF1508-domain-containing-protein	unknown	unknown	gnl\|CDD\|377831
NC_011852.1\|WP_005714539.1\|644805_645252_+\|hypothetical-protein	unknown	unknown	unknown
NC_011852.1\|WP_041603231.1\|636618_637047_-\|recombination-protein-NinB	unknown	unknown	gnl\|CDD\|368607
NC_011852.1\|WP_012621788.1\|635530_635908_-\|antitermination-protein	unknown	unknown	unknown
NC_011852.1\|WP_005714537.1\|644455_644746_-\|putative-addiction-module-antidote-protein	unknown	unknown	gnl\|CDD\|188241
NC_011852.1\|WP_012621833.1\|633066_633612_-\|lysozyme	unknown	unknown	gnl\|CDD\|381620
NC_011852.1\|WP_012621834.1\|633586_633862_-\|hypothetical-protein	unknown	unknown	unknown
NC_011852.1\|WP_010786731.1\|640189_640861_+\|helix-turn-helix-transcriptional-regulator	unknown	unknown	gnl\|CDD\|225484
NC_011852.1\|WP_010786729.1\|643611_644427_+\|DNA-adenine-methylase	unknown	unknown	gnl\|CDD\|223415
NC_011852.1\|WP_012621791.1\|637302_637974_-\|holin	unknown	unknown	gnl\|CDD\|369163
NC_011852.1\|WP_010786730.1\|641923_643567_+\|AAA-family-ATPase	unknown	unknown	gnl\|CDD\|224031

Protein	Function_ID	Function_description	E-value
NC_011852.1\|WP_010786732.1\|639862_640063_-\|helix-turn-helix-domain-containing-protein	gnl\|CDD\|374243	pfam15943, YdaS_antitoxin, Putative antitoxin of bacterial toxin-antitoxin system, YdaS/YdaT. YdaS_antitoxin is a family of putative bacterial antitoxins, neutralising the toxin YdaT, family pfam06254.	6.69213e-14
NC_011852.1\|WP_012621838.1\|638800_639583_-\|Rha-family-transcriptional-regulator	gnl\|CDD\|378235	pfam09669, Phage_pRha, Phage regulatory protein Rha (Phage_pRha). Members of this protein family are found in temperate phage and bacterial prophage regions. Members include the product of the rha gene of the lambdoid phage phi-80, a late operon gene. The presence of this gene interferes with infection of bacterial strains that lack integration host factor (IHF), which regulates the rha gene. It is suggested that Rha is a phage regulatory protein.	1.10777e-13
NC_011852.1\|WP_012621789.1\|635904_636474_-\|recombination-protein-NinG	gnl\|CDD\|368603	pfam05766, NinG, Bacteriophage Lambda NinG protein. NinG or Rap is involved in recombination. Rap (recombination adept with plasmid) increases lambda-by-plasmid recombination catalyzed by Escherichia coli's RecBCD pathway.	1.75449e-79
NC_011852.1\|WP_005714534.1\|640941_641790_+\|KilA-N-domain-containing-protein	gnl\|CDD\|367917	pfam04383, KilA-N, KilA-N domain. The amino-terminal module of the D6R/N1R proteins defines a novel, conserved DNA-binding domain (the KilA-N domain) that is found in a wide range of proteins of large bacterial and eukaryotic DNA viruses. The KilA-N domain family also includes the previously defined APSES domain. The KilA-N and APSES domains may also share a common fold with the nucleic acid-binding modules of the LAGLIDADG nucleases and the amino-terminal domains of the tRNA endonuclease.	2.2788e-23
NC_011852.1\|WP_010786729.1\|643611_644427_+\|DNA-adenine-methylase	gnl\|CDD\|223415	COG0338, Dam, Site-specific DNA methylase [DNA replication, recombination, and repair].	5.67268e-24
NC_011852.1\|WP_005714781.1\|634830_635007_-\|hypothetical-protein	gnl\|CDD\|224705	COG1792, MreC, Cell shape-determining protein [Cell envelope biogenesis, outer membrane].	0.000426805
NC_011852.1\|WP_010786728.1\|645696_645867_-\|DUF1508-domain-containing-protein	gnl\|CDD\|377831	pfam07411, DUF1508, Domain of unknown function (DUF1508). This family represents a series of bacterial domains of unknown function of around 50 residues in length. Members of this family are often found as tandem repeats and in some cases represent the whole protein. All member proteins are described as being hypothetical.	2.64791e-19
NC_011852.1\|WP_041603231.1\|636618_637047_-\|recombination-protein-NinB	gnl\|CDD\|368607	pfam05772, NinB, NinB protein. The ninR region of phage lambda contains two recombination genes, orf (ninB) and rap (ninG), that have roles when the RecF and RecBCD recombination pathways of E. coli, respectively, operate on phage lambda. NinB binds to single-stranded DNA.	7.43928e-64
NC_011852.1\|WP_005714537.1\|644455_644746_-\|putative-addiction-module-antidote-protein	gnl\|CDD\|188241	TIGR02684, conserved_hypothetical_protein, probable addiction module antidote protein. Members of this strictly bacterial protein family are small, at roughly 100 amino acids. The gene is almost invariably the downstream member of a gene pair. It is a predicted DNA-binding protein from a clade within Pfam helix-turn-helix family pfam01381. These gene pairs, when found on the bacterial chromosome, are located often with prophage regions, but also both in integrated plasmid regions and in housekeeping gene regions. Analysis suggests that the gene pair may serve as an addiction module. [Mobile and extrachromosomal element functions, Other].	1.58436e-38
NC_011852.1\|WP_012621833.1\|633066_633612_-\|lysozyme	gnl\|CDD\|381620	cd16901, lyz_P1, P1 lysozyme Lyz-like proteins. Enterobacteria phage P1 lysozyme Lyz is secreted to the Escherichia coli periplasm where it is membrane bound and inactive. Activation involves the release from the membrane, an intramolecular thiol-disulfide isomerization and extensive structural rearrangement of the N-terminal region. The dsDNA phages of eubacteria use endolysins or muralytic enzymes in conjunction with hollin, a small membrane protein, to degrade the peptidoglycan found in bacterial cell walls. Similarly, bacteria produce autolysins to facilitate the biosynthesis of its cell wall heteropolymer peptidoglycan and cell division. Endolysins and autolysins are found in viruses and bacteria, respectively. Both endolysin and autolysin enzymes cleave the glycosidic beta 1,4-bonds between the N-acetylmuramic acid and the N-acetylglucosamine of the peptidoglycan.	4.00937e-71
NC_011852.1\|WP_010786731.1\|640189_640861_+\|helix-turn-helix-transcriptional-regulator	gnl\|CDD\|225484	COG2932, COG2932, Predicted transcriptional regulator [Transcription].	3.86245e-24
NC_011852.1\|WP_012621791.1\|637302_637974_-\|holin	gnl\|CDD\|369163	pfam06992, Phage_lambda_P, Replication protein P. This family consists of several Bacteriophage lambda replication protein P like proteins. The bacteriophage lambda P protein promoters replication of the phage chromosome by recruiting a key component of the cellular replication machinery to the viral origin. Specifically, P protein delivers one or more molecules of Escherichia coli DnaB helicase to a nucleoprotein structure formed by the lambda O initiator at the lambda replication origin.	1.5041e-76
NC_011852.1\|WP_010786730.1\|641923_643567_+\|AAA-family-ATPase	gnl\|CDD\|224031	COG1106, COG1106, Predicted ATPases [General function prediction only].	3.65475e-09

>NC_011852.1|WP_012621791.1|637302_637974_-|holin
MQNVASMNLKSLVGQEPNYQVPAKTTAIPDGAIRAVNQLFIQLRAIFPAWKNSFPDADSYREAKRIWLETLVNEKITTIEQLQNGIERAKKSKNPFWPSVGEFVEWCKTVDYEALGLPDEDKLYKRLQAFMAFGMEEIQKFKFVSTAEYYLITGLYVRNRAGEWSDKQLKDEIKKSLVKMSKRLKTGEVLPEPKLALPQEVKAVNSEKVRAFWGGLLKQVRGF
>NC_011852.1|WP_071610285.1|637082_637280_-|hypothetical-protein
MSDYKCPKCGGELEDLSINDDWGWHVEEPYRCNGHYTGRFPNISKDCAMNRTKSCGYFTKEQVKK
>NC_011852.1|WP_041603231.1|636618_637047_-|recombination-protein-NinB
MEYKQKYFLRTEQIKNNALEFVKALPIDEKKPLVVDVKPATRNLKQNAKFHAMCVDIARQVQFNGEWLPLEAWKVLLISAHAEATKEGSCLVTGLEGELVNIRESTAQMSVKRMASLIEYATSWGVSNGVHFNDRWNFWGVK
>NC_011852.1|WP_012621789.1|635904_636474_-|recombination-protein-NinG
MIKPKVKTRKCKCCGGEFKSADSFRKWCSAECGVKLAKIAQEKARQKAIEKRNREERAKIKATRERLKSRSEWLKDAQAVFNEYIRLRDKDEPCISCQRFHQGQYHAGHYRTVKAMPELRFNEDNVHKQCSACNNHLSGNITEYRINLVRKIGVERVEALESYHPPVKWSAEDCKEIIKTYRAKIKELK
>NC_011852.1|WP_012621788.1|635530_635908_-|antitermination-protein
MIRLHISIDDILNVWVRRWASHRGCRGYPSLQSFMPEATVKITKYSIDELSEEHYLKLDEAVMTLHDLNLEAYQVLMAVFLQGQDKKNICLEMHISPRTYDNRLRTARDFMEGAVFGSGLIRLKF
>NC_011852.1|WP_012621837.1|635303_635522_+|hypothetical-protein
MANSMTEHSRKLRSKTANEYNKRMLAEGKVKQFSVRMETPVADEFVAILAEIGGKKAEAIKKLCEIYRQHQA
>NC_011852.1|WP_005714781.1|634830_635007_-|hypothetical-protein
MFNFRKQKQQVELIEQLQAEIEELKAENYRLRDLLSREWQEKRRFMKMINGKKKIATD
>NC_011852.1|WP_012621835.1|633975_634539_+|hypothetical-protein
MYFREGYTKFPYRPSNGSDDCQNPTPNAGGIDLVNHPEKIDEILEIAQLPELKTTLIELNKPDSPFITLGCSHWIGKYDNSHFSYIEFTFKDAKIANDFNFLVQLEKNLHLFFIEKLTTGFTKEQRDSYATYLKDRAQVYFRKIQYQDDLELRNLLGLEFHFQDRQMVDFHHKALRHFLTQHLVLSL
>NC_011852.1|WP_012621834.1|633586_633862_-|hypothetical-protein
MKNVMRDMGTQTYIWSGFSGIIAWLSEQQNLMILSLAIGIVTACANLYQRCDEGKAKRRERERAEEAHQIRMQIYRVRAERLSNEQAKKTG
>NC_011852.1|WP_012621833.1|633066_633612_-|lysozyme
MSKLRKLGKFGGGVCFVSAIIAVLNTDFHGQFRTSKQGLEIIGDAEGCKREPYLCPANVLTVGIGSTEASSGKIERKVYTDKEIAQRWLVDIQHAEKCVKRYANGGDIPQSVFDAATSLTFNAGCGTVSKSTFFRKIKSGDYVGACNELPKWVYSGGKKLRGLEIRREKEKALCLAGLIKS
>NC_011852.1|WP_012621838.1|638800_639583_-|Rha-family-transcriptional-regulator
MLLANKNPRCNVGNGEIMFMKTELLSLNQKENATLTMSSREIARITESRHRDVCLSIRNLMNKGVIGGYAESPYTHEQNGQVYYEYHINKRDTYVIVAQFSPEFTARLVDRWQELEQKQVQQLPSYSEALRQLADKIEESEQKSLQIASMESYFRNGISPFEFVKGLNGVNALKIGAFLVDKNWLYQDGNHKRVKSYARDQYLTEETTEISQHGKDPFVGYKPVLLKKGAAKLYEWYTKRELPMKANWNGVFTQDKVVGL
>NC_011852.1|WP_010786732.1|639862_640063_-|helix-turn-helix-domain-containing-protein
MNKVIDKAISECGSRDKLATACGVSVMTVSNWVRGFGIKAKHIKLISDATNGKISVDEILQSVTEG
>NC_011852.1|WP_010786731.1|640189_640861_+|helix-turn-helix-transcriptional-regulator
MSTLGERIEQAMNLKGLKRKELAEMLNISTMAVGDLINNKTKKPRYLVEIAEALNVDVKWLQTGEGEMRSHVNDVDVIDKDKDYSNTHINIDMYDIKLSAGNGKPVIEWVPRKSDEPLLFREAWFKVKRLSPKNCKAMYVRGHSMAPVLEDWDTVIVDISDTEIADGEVYAVVYNKHFYIKQIIRTGKGIQLVSFNPEYYPIDVMDDDLNNLQIIGRKVWRGG
>NC_011852.1|WP_005714534.1|640941_641790_+|KilA-N-domain-containing-protein
MVPNDVIIVQETEIRVTERNGEDYISLTDMCKAFGDGDQLIKNWLQNKNTIEFLQVWEEINNPNFNLVELHQIKNNIGLNRFVMSVKKWSATNAIGLIAKTGRYGSGTYAHKDIALEFGSWLSPEFKLYLIKEFQRLKQKEAQENKTEWNVKRILSKANYRIHTDAIQAHLIPRLLNSTQPIFVYSAEADILNQAMFGLTAKQWREQNPTLKGNIRDYASVEQLTVLAALESQNALLIEQGVSQKERLTILNRLAIQQMQSLLKSKSLEPLKDKPLLIEDRE
>NC_011852.1|WP_010786730.1|641923_643567_+|AAA-family-ATPase
MITNLNIIHYRKLKNLSLAFKPGINLISGTNGTCKSSILHIIGNAFQRFKRTSDGVDSSSLSVINAINKYTNPKVENLTKGDKTYNDPAKGTEGELFNIQLDNETYAFRRHNSQDELEDGEFKNRFRLILKYPRGEKQSLPFGMVIYLGLSRIVPVGELEDYTEEIKKNLPAKYQDELISLYQKMTDISITEPCIENSNEIKHRISFKSEVDGIDSDTISAGEDNIMIILTALVSLKYHFESCSNEEYKKSYLLIDEFDATLHPSLQFKLLSLLREFSRDFNIQIIFTTHSLYLIDKALKAEDNIIYLMKLANNSVAIMQNPDIFKIEMHLNSETRQDLYRDKKLPIFSEDNEARIMINFIFDILSEKDQKFASIRHYFHLVQMKSGCDNLKTLFKDKVLTANTLKAMCILDGDNRTHELTHNIISLPGQASPEKLTFQHLSELISKEIYNDFWFNEYLQQEGYSFEWVKSNVFPRASGLVSAYDRDKAKSLFNEQSYHHFFTIVMKDWLLRHWEDREMKGFIKDLNILFHNLADYYGIHTAYWPRL
>NC_011852.1|WP_010786729.1|643611_644427_+|DNA-adenine-methylase
MLHTPLRYPGGKAKFAPIIKQIIEQNNLKGHYVEPYAGGAGVALDLLFSGYCSDIHINDLDLAIFNFWKSITERTDDFIRLVNDTPITIEEWHKQKILLRREDISPLEHGFAAFFLNRTNRSGILKAGVIGGLKQSGDYKLDCRFNKTDLIKRIEKIGNVAKKIHVTNFDTENWLPIINKLVPSNSLIYLDPPYYEKGQGLYRNFYQHKDHVEVKNQLANIKTPWIVSYDNNPNIKEIYNKYRQQEYMLNYSANKKMKATEIVIYSNNLII
>NC_011852.1|WP_005714537.1|644455_644746_-|putative-addiction-module-antidote-protein
MVELQDFDMAEHLRSEEEIQLYLNEVLKEDDVDLILSALGDIAKARNMSQIAREAGVSREGLYKAFSGKGNPTFSTVLKVMRALNLTFEVKQAVHT
>NC_011852.1|WP_005714539.1|644805_645252_+|hypothetical-protein
MPLYENAKALIRQNLTEISQGKKAKLQVIGSFTDKQFLDINQHRKKAELPPLECNEIVYIGRHHYQSRSKDGYNINDMVKQAESALSVHSCLVPSNRATALENPHQRHDGYGNLVNDRAILELTSKKPRAELFSVIPKGDSIKPNDDQ
>NC_011852.1|WP_010786728.1|645696_645867_-|DUF1508-domain-containing-protein
MYFQIFQGVNGQWYWRLKSANHETIASSEGYTTKQNCLHCIGLVMDTTQKTPVYEV
>NC_011852.1|WP_012621839.1|645881_646103_+|hypothetical-protein
MHEKMKCYAVSYSFDGKKWATEIYANSFEEAQEKVKAMSQATVDGEIHLSVYIPENPLSKIARLMRRLFQKGG

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Click the colored protein region to show detailed information

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity
NC_011852_1	1.1\|225205\|40\|NC_011852\|CRISPRCasFinder	225205-225244	40	NC_011852.1	6723-6762	0	1.0
NC_011852_1	1.2\|225277\|49\|NC_011852\|CRISPRCasFinder	225277-225325	49	NC_011852.1	6642-6690	0	1.0
NC_011852_1	1.2\|225277\|49\|NC_011852\|CRISPRCasFinder	225277-225325	49	NC_011852.1	2021106-2021154	0	1.0
NC_011852_1	1.4\|225457\|58\|NC_011852\|CRISPRCasFinder	225457-225514	58	NC_011852.1	6453-6510	0	1.0
NC_011852_1	1.5\|225547\|31\|NC_011852\|CRISPRCasFinder	225547-225577	31	NC_011852.1	6327-6357	0	1.0
NC_011852_1	1.5\|225547\|31\|NC_011852\|CRISPRCasFinder	225547-225577	31	NC_011852.1	6390-6420	0	1.0
NC_011852_1	1.5\|225547\|31\|NC_011852\|CRISPRCasFinder	225547-225577	31	NC_011852.1	700326-700356	0	1.0
NC_011852_1	1.6\|225610\|31\|NC_011852\|CRISPRCasFinder	225610-225640	31	NC_011852.1	6327-6357	0	1.0
NC_011852_1	1.6\|225610\|31\|NC_011852\|CRISPRCasFinder	225610-225640	31	NC_011852.1	6390-6420	0	1.0
NC_011852_1	1.6\|225610\|31\|NC_011852\|CRISPRCasFinder	225610-225640	31	NC_011852.1	700326-700356	0	1.0
NC_011852_1	1.7\|225673\|22\|NC_011852\|CRISPRCasFinder	225673-225694	22	NC_011852.1	6273-6294	0	1.0
NC_011852_1	1.8\|225727\|22\|NC_011852\|CRISPRCasFinder	225727-225748	22	NC_011852.1	483801-483822	0	1.0
NC_011852_1	1.9\|225781\|22\|NC_011852\|CRISPRCasFinder	225781-225802	22	NC_011852.1	406239-406260	0	1.0
NC_011852_1	1.9\|225781\|22\|NC_011852\|CRISPRCasFinder	225781-225802	22	NC_011852.1	483738-483759	0	1.0
NC_011852_1	1.9\|225781\|22\|NC_011852\|CRISPRCasFinder	225781-225802	22	NC_011852.1	541379-541400	0	1.0
NC_011852_1	1.2\|225277\|49\|NC_011852\|CRISPRCasFinder	225277-225325	49	NC_011852.1	483855-483903	1	0.98
NC_011852_1	1.4\|225457\|58\|NC_011852\|CRISPRCasFinder	225457-225514	58	NC_011852.1	700389-700446	1	0.983
NC_011852_1	1.5\|225547\|31\|NC_011852\|CRISPRCasFinder	225547-225577	31	NC_011852.1	406005-406035	1	0.968
NC_011852_1	1.5\|225547\|31\|NC_011852\|CRISPRCasFinder	225547-225577	31	NC_011852.1	539678-539708	1	0.968
NC_011852_1	1.5\|225547\|31\|NC_011852\|CRISPRCasFinder	225547-225577	31	NC_011852.1	540641-540671	1	0.968
NC_011852_1	1.5\|225547\|31\|NC_011852\|CRISPRCasFinder	225547-225577	31	NC_011852.1	564437-564467	1	0.968
NC_011852_1	1.5\|225547\|31\|NC_011852\|CRISPRCasFinder	225547-225577	31	NC_011852.1	940607-940637	1	0.968
NC_011852_1	1.6\|225610\|31\|NC_011852\|CRISPRCasFinder	225610-225640	31	NC_011852.1	406005-406035	1	0.968
NC_011852_1	1.6\|225610\|31\|NC_011852\|CRISPRCasFinder	225610-225640	31	NC_011852.1	539678-539708	1	0.968
NC_011852_1	1.6\|225610\|31\|NC_011852\|CRISPRCasFinder	225610-225640	31	NC_011852.1	540641-540671	1	0.968
NC_011852_1	1.6\|225610\|31\|NC_011852\|CRISPRCasFinder	225610-225640	31	NC_011852.1	564437-564467	1	0.968
NC_011852_1	1.6\|225610\|31\|NC_011852\|CRISPRCasFinder	225610-225640	31	NC_011852.1	940607-940637	1	0.968
NC_011852_1	1.7\|225673\|22\|NC_011852\|CRISPRCasFinder	225673-225694	22	NC_011852.1	6453-6474	1	0.955
NC_011852_1	1.7\|225673\|22\|NC_011852\|CRISPRCasFinder	225673-225694	22	NC_011852.1	406059-406080	1	0.955
NC_011852_1	1.7\|225673\|22\|NC_011852\|CRISPRCasFinder	225673-225694	22	NC_011852.1	540596-540617	1	0.955
NC_011852_1	1.7\|225673\|22\|NC_011852\|CRISPRCasFinder	225673-225694	22	NC_011852.1	700389-700410	1	0.955
NC_011852_1	1.7\|225673\|22\|NC_011852\|CRISPRCasFinder	225673-225694	22	NC_011852.1	1491993-1492014	1	0.955
NC_011852_1	1.8\|225727\|22\|NC_011852\|CRISPRCasFinder	225727-225748	22	NC_011852.1	6192-6213	1	0.955
NC_011852_1	1.8\|225727\|22\|NC_011852\|CRISPRCasFinder	225727-225748	22	NC_011852.1	700209-700230	1	0.955
NC_011852_1	1.9\|225781\|22\|NC_011852\|CRISPRCasFinder	225781-225802	22	NC_011852.1	1727762-1727783	1	0.955
NC_011852_1	1.9\|225781\|22\|NC_011852\|CRISPRCasFinder	225781-225802	22	NC_011852.1	2020782-2020803	1	0.955
NC_011852_1	1.10\|225835\|22\|NC_011852\|CRISPRCasFinder	225835-225856	22	NC_011852.1	6246-6267	1	0.955
NC_011852_1	1.10\|225835\|22\|NC_011852\|CRISPRCasFinder	225835-225856	22	NC_011852.1	405645-405666	1	0.955
NC_011852_1	1.10\|225835\|22\|NC_011852\|CRISPRCasFinder	225835-225856	22	NC_011852.1	940328-940349	1	0.955
NC_011852_1	1.10\|225835\|22\|NC_011852\|CRISPRCasFinder	225835-225856	22	NC_011852.1	1490967-1490988	1	0.955
NC_011852_1	1.5\|225547\|31\|NC_011852\|CRISPRCasFinder	225547-225577	31	NC_011852.1	483963-483993	2	0.935
NC_011852_1	1.5\|225547\|31\|NC_011852\|CRISPRCasFinder	225547-225577	31	NC_011852.1	539840-539870	2	0.935
NC_011852_1	1.5\|225547\|31\|NC_011852\|CRISPRCasFinder	225547-225577	31	NC_011852.1	1493118-1493148	2	0.935
NC_011852_1	1.6\|225610\|31\|NC_011852\|CRISPRCasFinder	225610-225640	31	NC_011852.1	483963-483993	2	0.935
NC_011852_1	1.6\|225610\|31\|NC_011852\|CRISPRCasFinder	225610-225640	31	NC_011852.1	539840-539870	2	0.935
NC_011852_1	1.6\|225610\|31\|NC_011852\|CRISPRCasFinder	225610-225640	31	NC_011852.1	1493118-1493148	2	0.935
NC_011852_1	1.7\|225673\|22\|NC_011852\|CRISPRCasFinder	225673-225694	22	NC_011852.1	484071-484092	2	0.909
NC_011852_1	1.8\|225727\|22\|NC_011852\|CRISPRCasFinder	225727-225748	22	NC_011852.1	700236-700257	2	0.909
NC_011852_1	1.8\|225727\|22\|NC_011852\|CRISPRCasFinder	225727-225748	22	NC_011852.1	1727717-1727738	2	0.909
NC_011852_1	1.8\|225727\|22\|NC_011852\|CRISPRCasFinder	225727-225748	22	NC_011852.1	1727771-1727792	2	0.909
NC_011852_1	1.8\|225727\|22\|NC_011852\|CRISPRCasFinder	225727-225748	22	NC_011852.1	2020773-2020794	2	0.909
NC_011852_1	1.9\|225781\|22\|NC_011852\|CRISPRCasFinder	225781-225802	22	NC_011852.1	6228-6249	2	0.909
NC_011852_1	1.9\|225781\|22\|NC_011852\|CRISPRCasFinder	225781-225802	22	NC_011852.1	225880-225901	2	0.909
NC_011852_1	1.9\|225781\|22\|NC_011852\|CRISPRCasFinder	225781-225802	22	NC_011852.1	700218-700239	2	0.909
NC_011852_1	1.9\|225781\|22\|NC_011852\|CRISPRCasFinder	225781-225802	22	NC_011852.1	700245-700266	2	0.909
NC_011852_1	1.9\|225781\|22\|NC_011852\|CRISPRCasFinder	225781-225802	22	NC_011852.1	940697-940718	2	0.909
NC_011852_1	1.9\|225781\|22\|NC_011852\|CRISPRCasFinder	225781-225802	22	NC_011852.1	1727708-1727729	2	0.909
NC_011852_1	1.9\|225781\|22\|NC_011852\|CRISPRCasFinder	225781-225802	22	NC_011852.1	1727735-1727756	2	0.909
NC_011852_1	1.10\|225835\|22\|NC_011852\|CRISPRCasFinder	225835-225856	22	NC_011852.1	406086-406107	2	0.909
NC_011852_1	1.10\|225835\|22\|NC_011852\|CRISPRCasFinder	225835-225856	22	NC_011852.1	541172-541193	2	0.909
NC_011852_1	1.10\|225835\|22\|NC_011852\|CRISPRCasFinder	225835-225856	22	NC_011852.1	700236-700257	2	0.909
NC_011852_1	1.10\|225835\|22\|NC_011852\|CRISPRCasFinder	225835-225856	22	NC_011852.1	700362-700383	2	0.909
NC_011852_1	1.10\|225835\|22\|NC_011852\|CRISPRCasFinder	225835-225856	22	NC_011852.1	1492947-1492968	2	0.909
NC_011852_1	1.10\|225835\|22\|NC_011852\|CRISPRCasFinder	225835-225856	22	NC_011852.1	1727321-1727342	2	0.909
NC_011852_1	1.10\|225835\|22\|NC_011852\|CRISPRCasFinder	225835-225856	22	NC_011852.1	1727663-1727684	2	0.909
NC_011852_1	1.10\|225835\|22\|NC_011852\|CRISPRCasFinder	225835-225856	22	NC_011852.1	1727717-1727738	2	0.909
NC_011852_1	1.10\|225835\|22\|NC_011852\|CRISPRCasFinder	225835-225856	22	NC_011852.1	2021052-2021073	2	0.909
NC_011852_1	1.3\|225358\|67\|NC_011852\|CRISPRCasFinder	225358-225424	67	NC_011852.1	6543-6609	7	0.896
NC_011852_1	1.3\|225358\|67\|NC_011852\|CRISPRCasFinder	225358-225424	67	NC_011852.1	6795-6861	7	0.896
NC_011852_1	1.3\|225358\|67\|NC_011852\|CRISPRCasFinder	225358-225424	67	NC_011852.1	225106-225172	7	0.896

1. spacer 1.1|225205|40|NC_011852|CRISPRCasFinder matches to position: 6723-6762, mismatch: 0, identity: 1.0

tgaaccaggacaagcgggtccagcaggtcctagaggtgaa	CRISPR spacer
tgaaccaggacaagcgggtccagcaggtcctagaggtgaa	Protospacer
****************************************

2. spacer 1.2|225277|49|NC_011852|CRISPRCasFinder matches to position: 6642-6690, mismatch: 0, identity: 1.0

accgcagggaacagcgggtgctcagggacctaagggggataaaggcgat	CRISPR spacer
accgcagggaacagcgggtgctcagggacctaagggggataaaggcgat	Protospacer
*************************************************

3. spacer 1.2|225277|49|NC_011852|CRISPRCasFinder matches to position: 2021106-2021154, mismatch: 0, identity: 1.0

accgcagggaacagcgggtgctcagggacctaagggggataaaggcgat	CRISPR spacer
accgcagggaacagcgggtgctcagggacctaagggggataaaggcgat	Protospacer
*************************************************

4. spacer 1.4|225457|58|NC_011852|CRISPRCasFinder matches to position: 6453-6510, mismatch: 0, identity: 1.0

ccctgcgggtcctaaaggagatgcaggtccaaaaggtgatacaggtcagagaggtgaa	CRISPR spacer
ccctgcgggtcctaaaggagatgcaggtccaaaaggtgatacaggtcagagaggtgaa	Protospacer
**********************************************************

5. spacer 1.5|225547|31|NC_011852|CRISPRCasFinder matches to position: 6327-6357, mismatch: 0, identity: 1.0

tgaaccgggtcctaaaggtgaacaaggtatt	CRISPR spacer
tgaaccgggtcctaaaggtgaacaaggtatt	Protospacer
*******************************

6. spacer 1.5|225547|31|NC_011852|CRISPRCasFinder matches to position: 6390-6420, mismatch: 0, identity: 1.0

tgaaccgggtcctaaaggtgaacaaggtatt	CRISPR spacer
tgaaccgggtcctaaaggtgaacaaggtatt	Protospacer
*******************************

7. spacer 1.5|225547|31|NC_011852|CRISPRCasFinder matches to position: 700326-700356, mismatch: 0, identity: 1.0

tgaaccgggtcctaaaggtgaacaaggtatt	CRISPR spacer
tgaaccgggtcctaaaggtgaacaaggtatt	Protospacer
*******************************

8. spacer 1.6|225610|31|NC_011852|CRISPRCasFinder matches to position: 6327-6357, mismatch: 0, identity: 1.0

tgaaccgggtcctaaaggtgaacaaggtatt	CRISPR spacer
tgaaccgggtcctaaaggtgaacaaggtatt	Protospacer
*******************************

9. spacer 1.6|225610|31|NC_011852|CRISPRCasFinder matches to position: 6390-6420, mismatch: 0, identity: 1.0

tgaaccgggtcctaaaggtgaacaaggtatt	CRISPR spacer
tgaaccgggtcctaaaggtgaacaaggtatt	Protospacer
*******************************

10. spacer 1.6|225610|31|NC_011852|CRISPRCasFinder matches to position: 700326-700356, mismatch: 0, identity: 1.0

tgaaccgggtcctaaaggtgaacaaggtatt	CRISPR spacer
tgaaccgggtcctaaaggtgaacaaggtatt	Protospacer
*******************************

11. spacer 1.7|225673|22|NC_011852|CRISPRCasFinder matches to position: 6273-6294, mismatch: 0, identity: 1.0

tgatacaggtcagaaaggtgaa	CRISPR spacer
tgatacaggtcagaaaggtgaa	Protospacer
**********************

12. spacer 1.8|225727|22|NC_011852|CRISPRCasFinder matches to position: 483801-483822, mismatch: 0, identity: 1.0

ccctgcgagtccaacgggatca	CRISPR spacer
ccctgcgagtccaacgggatca	Protospacer
**********************

13. spacer 1.9|225781|22|NC_011852|CRISPRCasFinder matches to position: 406239-406260, mismatch: 0, identity: 1.0

accacaaggacctacgggtcca	CRISPR spacer
accacaaggacctacgggtcca	Protospacer
**********************

14. spacer 1.9|225781|22|NC_011852|CRISPRCasFinder matches to position: 483738-483759, mismatch: 0, identity: 1.0

accacaaggacctacgggtcca	CRISPR spacer
accacaaggacctacgggtcca	Protospacer
**********************

15. spacer 1.9|225781|22|NC_011852|CRISPRCasFinder matches to position: 541379-541400, mismatch: 0, identity: 1.0

accacaaggacctacgggtcca	CRISPR spacer
accacaaggacctacgggtcca	Protospacer
**********************

16. spacer 1.2|225277|49|NC_011852|CRISPRCasFinder matches to position: 483855-483903, mismatch: 1, identity: 0.98

accgcagggaacagcgggtgctcagggacctaagggggataaaggcgat	CRISPR spacer
accgcagggaacagcgggtgctcaggaacctaagggggataaaggcgat	Protospacer
**************************.**********************

17. spacer 1.4|225457|58|NC_011852|CRISPRCasFinder matches to position: 700389-700446, mismatch: 1, identity: 0.983

ccctgcgggtcctaaaggagatgcaggtccaaaaggtgatacaggtcagagaggtgaa	CRISPR spacer
ccctgcaggtcctaaaggagatgcaggtccaaaaggtgatacaggtcagagaggtgaa	Protospacer
******.***************************************************

18. spacer 1.5|225547|31|NC_011852|CRISPRCasFinder matches to position: 406005-406035, mismatch: 1, identity: 0.968

tgaaccgggtcctaaaggtgaacaaggtatt	CRISPR spacer
tgaacagggtcctaaaggtgaacaaggtatt	Protospacer
***** *************************

19. spacer 1.5|225547|31|NC_011852|CRISPRCasFinder matches to position: 539678-539708, mismatch: 1, identity: 0.968

tgaaccgggtcctaaaggtgaacaaggtatt	CRISPR spacer
tgaacagggtcctaaaggtgaacaaggtatt	Protospacer
***** *************************

20. spacer 1.5|225547|31|NC_011852|CRISPRCasFinder matches to position: 540641-540671, mismatch: 1, identity: 0.968

tgaaccgggtcctaaaggtgaacaaggtatt	CRISPR spacer
tgaaccgggtcctaaaggtgaaccaggtatt	Protospacer
*********************** *******

21. spacer 1.5|225547|31|NC_011852|CRISPRCasFinder matches to position: 564437-564467, mismatch: 1, identity: 0.968

tgaaccgggtcctaaaggtgaacaaggtatt	CRISPR spacer
tgaacagggtcctaaaggtgaacaaggtatt	Protospacer
***** *************************

22. spacer 1.5|225547|31|NC_011852|CRISPRCasFinder matches to position: 940607-940637, mismatch: 1, identity: 0.968

tgaaccgggtcctaaaggtgaacaaggtatt	CRISPR spacer
tgaacagggtcctaaaggtgaacaaggtatt	Protospacer
***** *************************

23. spacer 1.6|225610|31|NC_011852|CRISPRCasFinder matches to position: 406005-406035, mismatch: 1, identity: 0.968

tgaaccgggtcctaaaggtgaacaaggtatt	CRISPR spacer
tgaacagggtcctaaaggtgaacaaggtatt	Protospacer
***** *************************

24. spacer 1.6|225610|31|NC_011852|CRISPRCasFinder matches to position: 539678-539708, mismatch: 1, identity: 0.968

tgaaccgggtcctaaaggtgaacaaggtatt	CRISPR spacer
tgaacagggtcctaaaggtgaacaaggtatt	Protospacer
***** *************************

25. spacer 1.6|225610|31|NC_011852|CRISPRCasFinder matches to position: 540641-540671, mismatch: 1, identity: 0.968

tgaaccgggtcctaaaggtgaacaaggtatt	CRISPR spacer
tgaaccgggtcctaaaggtgaaccaggtatt	Protospacer
*********************** *******

26. spacer 1.6|225610|31|NC_011852|CRISPRCasFinder matches to position: 564437-564467, mismatch: 1, identity: 0.968

tgaaccgggtcctaaaggtgaacaaggtatt	CRISPR spacer
tgaacagggtcctaaaggtgaacaaggtatt	Protospacer
***** *************************

27. spacer 1.6|225610|31|NC_011852|CRISPRCasFinder matches to position: 940607-940637, mismatch: 1, identity: 0.968

tgaaccgggtcctaaaggtgaacaaggtatt	CRISPR spacer
tgaacagggtcctaaaggtgaacaaggtatt	Protospacer
***** *************************

28. spacer 1.7|225673|22|NC_011852|CRISPRCasFinder matches to position: 6453-6474, mismatch: 1, identity: 0.955

tgatacaggtcagaaaggtgaa	CRISPR spacer
tgatacaggtcagagaggtgaa	Protospacer
**************.*******

29. spacer 1.7|225673|22|NC_011852|CRISPRCasFinder matches to position: 406059-406080, mismatch: 1, identity: 0.955

tgatacaggtcagaaaggtgaa	CRISPR spacer
tgataccggtcagaaaggtgaa	Protospacer
****** ***************

30. spacer 1.7|225673|22|NC_011852|CRISPRCasFinder matches to position: 540596-540617, mismatch: 1, identity: 0.955

tgatacaggtcagaaaggtgaa	CRISPR spacer
tgataccggtcagaaaggtgaa	Protospacer
****** ***************

31. spacer 1.7|225673|22|NC_011852|CRISPRCasFinder matches to position: 700389-700410, mismatch: 1, identity: 0.955

tgatacaggtcagaaaggtgaa	CRISPR spacer
tgatacaggtcagagaggtgaa	Protospacer
**************.*******

32. spacer 1.7|225673|22|NC_011852|CRISPRCasFinder matches to position: 1491993-1492014, mismatch: 1, identity: 0.955

tgatacaggtcagaaaggtgaa	CRISPR spacer
tgatactggtcagaaaggtgaa	Protospacer
****** ***************

33. spacer 1.8|225727|22|NC_011852|CRISPRCasFinder matches to position: 6192-6213, mismatch: 1, identity: 0.955

ccctgcgagtccaacgggatca	CRISPR spacer
ccctgcgggtccaacgggatca	Protospacer
*******.**************

34. spacer 1.8|225727|22|NC_011852|CRISPRCasFinder matches to position: 700209-700230, mismatch: 1, identity: 0.955

ccctgcgagtccaacgggatca	CRISPR spacer
ccctgcgggtccaacgggatca	Protospacer
*******.**************

35. spacer 1.9|225781|22|NC_011852|CRISPRCasFinder matches to position: 1727762-1727783, mismatch: 1, identity: 0.955

accacaaggacctacgggtcca	CRISPR spacer
accacaaggccctacgggtcca	Protospacer
********* ************

36. spacer 1.9|225781|22|NC_011852|CRISPRCasFinder matches to position: 2020782-2020803, mismatch: 1, identity: 0.955

accacaaggacctacgggtcca	CRISPR spacer
accacaaggccctacgggtcca	Protospacer
********* ************

37. spacer 1.10|225835|22|NC_011852|CRISPRCasFinder matches to position: 6246-6267, mismatch: 1, identity: 0.955

ccctgcgggtccagcaggacca	CRISPR spacer
ccctgcgggtccagcgggacca	Protospacer
***************.******

38. spacer 1.10|225835|22|NC_011852|CRISPRCasFinder matches to position: 405645-405666, mismatch: 1, identity: 0.955

ccctgcgggtccagcaggacca	CRISPR spacer
ccctgcgggtccagcaggtcca	Protospacer
****************** ***

39. spacer 1.10|225835|22|NC_011852|CRISPRCasFinder matches to position: 940328-940349, mismatch: 1, identity: 0.955

ccctgcgggtccagcaggacca	CRISPR spacer
ccctgcgggtccagcaggtcca	Protospacer
****************** ***

40. spacer 1.10|225835|22|NC_011852|CRISPRCasFinder matches to position: 1490967-1490988, mismatch: 1, identity: 0.955

ccctgcgggtccagcaggacca	CRISPR spacer
ccctgcgggtccagcaggtcca	Protospacer
****************** ***

41. spacer 1.5|225547|31|NC_011852|CRISPRCasFinder matches to position: 483963-483993, mismatch: 2, identity: 0.935

tgaaccgggtcctaaaggtgaacaaggtatt	CRISPR spacer
tgaaccaggtcctaaaggtgaacaagggatt	Protospacer
******.******************** ***

42. spacer 1.5|225547|31|NC_011852|CRISPRCasFinder matches to position: 539840-539870, mismatch: 2, identity: 0.935

tgaaccgggtcctaaaggtgaacaaggtatt	CRISPR spacer
tgaaccaggtcctagaggtgaacaaggtatt	Protospacer
******.*******.****************

43. spacer 1.5|225547|31|NC_011852|CRISPRCasFinder matches to position: 1493118-1493148, mismatch: 2, identity: 0.935

tgaaccgggtcctaaaggtgaacaaggtatt	CRISPR spacer
tgaaccgggtcctagaggtgagcaaggtatt	Protospacer
**************.******.*********

44. spacer 1.6|225610|31|NC_011852|CRISPRCasFinder matches to position: 483963-483993, mismatch: 2, identity: 0.935

tgaaccgggtcctaaaggtgaacaaggtatt	CRISPR spacer
tgaaccaggtcctaaaggtgaacaagggatt	Protospacer
******.******************** ***

45. spacer 1.6|225610|31|NC_011852|CRISPRCasFinder matches to position: 539840-539870, mismatch: 2, identity: 0.935

tgaaccgggtcctaaaggtgaacaaggtatt	CRISPR spacer
tgaaccaggtcctagaggtgaacaaggtatt	Protospacer
******.*******.****************

46. spacer 1.6|225610|31|NC_011852|CRISPRCasFinder matches to position: 1493118-1493148, mismatch: 2, identity: 0.935

tgaaccgggtcctaaaggtgaacaaggtatt	CRISPR spacer
tgaaccgggtcctagaggtgagcaaggtatt	Protospacer
**************.******.*********

47. spacer 1.7|225673|22|NC_011852|CRISPRCasFinder matches to position: 484071-484092, mismatch: 2, identity: 0.909

tgatacaggtcagaaaggtgaa	CRISPR spacer
tgatacagatcagagaggtgaa	Protospacer
********.*****.*******

48. spacer 1.8|225727|22|NC_011852|CRISPRCasFinder matches to position: 700236-700257, mismatch: 2, identity: 0.909

ccctgcgagtccaacgggatca	CRISPR spacer
ccctgcgggtccaacgggacca	Protospacer
*******.***********.**

49. spacer 1.8|225727|22|NC_011852|CRISPRCasFinder matches to position: 1727717-1727738, mismatch: 2, identity: 0.909

ccctgcgagtccaacgggatca	CRISPR spacer
ccctgcgggtccaacgggacca	Protospacer
*******.***********.**

50. spacer 1.8|225727|22|NC_011852|CRISPRCasFinder matches to position: 1727771-1727792, mismatch: 2, identity: 0.909

ccctgcgagtccaacgggatca	CRISPR spacer
ccctacgggtccaacgggatca	Protospacer
****.**.**************

51. spacer 1.8|225727|22|NC_011852|CRISPRCasFinder matches to position: 2020773-2020794, mismatch: 2, identity: 0.909

ccctgcgagtccaacgggatca	CRISPR spacer
ccctacgggtccaacgggatca	Protospacer
****.**.**************

52. spacer 1.9|225781|22|NC_011852|CRISPRCasFinder matches to position: 6228-6249, mismatch: 2, identity: 0.909

accacaaggacctacgggtcca	CRISPR spacer
accacaaggtcctgcgggtcca	Protospacer
********* ***.********

53. spacer 1.9|225781|22|NC_011852|CRISPRCasFinder matches to position: 225880-225901, mismatch: 2, identity: 0.909

accacaaggacctacgggtcca	CRISPR spacer
accacaaggccctgcgggtcca	Protospacer
********* ***.********

54. spacer 1.9|225781|22|NC_011852|CRISPRCasFinder matches to position: 700218-700239, mismatch: 2, identity: 0.909

accacaaggacctacgggtcca	CRISPR spacer
accacaaggccctgcgggtcca	Protospacer
********* ***.********

55. spacer 1.9|225781|22|NC_011852|CRISPRCasFinder matches to position: 700245-700266, mismatch: 2, identity: 0.909

accacaaggacctacgggtcca	CRISPR spacer
accacaaggccctgcgggtcca	Protospacer
********* ***.********

56. spacer 1.9|225781|22|NC_011852|CRISPRCasFinder matches to position: 940697-940718, mismatch: 2, identity: 0.909

accacaaggacctacgggtcca	CRISPR spacer
accacaagaccctacgggtcca	Protospacer
********. ************

57. spacer 1.9|225781|22|NC_011852|CRISPRCasFinder matches to position: 1727708-1727729, mismatch: 2, identity: 0.909

accacaaggacctacgggtcca	CRISPR spacer
accacaaggccctgcgggtcca	Protospacer
********* ***.********

58. spacer 1.9|225781|22|NC_011852|CRISPRCasFinder matches to position: 1727735-1727756, mismatch: 2, identity: 0.909

accacaaggacctacgggtcca	CRISPR spacer
accacaagaccctacgggtcca	Protospacer
********. ************

59. spacer 1.10|225835|22|NC_011852|CRISPRCasFinder matches to position: 406086-406107, mismatch: 2, identity: 0.909

ccctgcgggtccagcaggacca	CRISPR spacer
ccctgcgggtccagtaggtcca	Protospacer
**************.*** ***

60. spacer 1.10|225835|22|NC_011852|CRISPRCasFinder matches to position: 541172-541193, mismatch: 2, identity: 0.909

ccctgcgggtccagcaggacca	CRISPR spacer
ccctgcgggtccagtaggtcca	Protospacer
**************.*** ***

61. spacer 1.10|225835|22|NC_011852|CRISPRCasFinder matches to position: 700236-700257, mismatch: 2, identity: 0.909

ccctgcgggtccagcaggacca	CRISPR spacer
ccctgcgggtccaacgggacca	Protospacer
*************.*.******

62. spacer 1.10|225835|22|NC_011852|CRISPRCasFinder matches to position: 700362-700383, mismatch: 2, identity: 0.909

ccctgcgggtccagcaggacca	CRISPR spacer
ccctgcaggtccagcgggacca	Protospacer
******.********.******

63. spacer 1.10|225835|22|NC_011852|CRISPRCasFinder matches to position: 1492947-1492968, mismatch: 2, identity: 0.909

ccctgcgggtccagcaggacca	CRISPR spacer
ccctgcgggtccagtaggtcca	Protospacer
**************.*** ***

64. spacer 1.10|225835|22|NC_011852|CRISPRCasFinder matches to position: 1727321-1727342, mismatch: 2, identity: 0.909

ccctgcgggtccagcaggacca	CRISPR spacer
ccctgcgggcccagcaggtcca	Protospacer
*********.******** ***

65. spacer 1.10|225835|22|NC_011852|CRISPRCasFinder matches to position: 1727663-1727684, mismatch: 2, identity: 0.909

ccctgcgggtccagcaggacca	CRISPR spacer
ccctgcgggcccagcaggtcca	Protospacer
*********.******** ***

66. spacer 1.10|225835|22|NC_011852|CRISPRCasFinder matches to position: 1727717-1727738, mismatch: 2, identity: 0.909

ccctgcgggtccagcaggacca	CRISPR spacer
ccctgcgggtccaacgggacca	Protospacer
*************.*.******

67. spacer 1.10|225835|22|NC_011852|CRISPRCasFinder matches to position: 2021052-2021073, mismatch: 2, identity: 0.909

ccctgcgggtccagcaggacca	CRISPR spacer
ccctgcgggtccagcgggtcca	Protospacer
***************.** ***

68. spacer 1.3|225358|67|NC_011852|CRISPRCasFinder matches to position: 6543-6609, mismatch: 7, identity: 0.896

tcctgcgggtccacctggtcctgtgggtccagcaggggctgctggtcctaagggggataa	CRISPR spacer
tcctgcgggtccacctggtcctgtgggtccagcaggggctgctggtcctaagggggataa	Protospacer
************************************************************

69. spacer 1.3|225358|67|NC_011852|CRISPRCasFinder matches to position: 6795-6861, mismatch: 7, identity: 0.896

tcctgcgggtccacctggtcctgtgggtccagcaggggctgctggtcctaagggggataa	CRISPR spacer
tcctgcgggtccacctggtcctgtgggtccagcaggggctgctggtcctaagggggataa	Protospacer
************************************************************

70. spacer 1.3|225358|67|NC_011852|CRISPRCasFinder matches to position: 225106-225172, mismatch: 7, identity: 0.896

tcctgcgggtccacctggtcctgtgggtccagcaggggctgctggtcctaagggggataa	CRISPR spacer
tcctgcgggtccacctggtcctgtgggtccagcaggggctgctggtcctaagggggataa	Protospacer
************************************************************

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NC_011852_1	1.9\|225781\|22\|NC_011852\|CRISPRCasFinder	225781-225802	22	MN585984	Mycobacterium phage AgronaGT15, complete genome	2077-2098	2	0.909
NC_011852_3	3.1\|576650\|25\|NC_011852\|CRISPRCasFinder	576650-576674	25	NZ_CP034302	Vibrio parahaemolyticus strain 20160303005-1 plasmid pVPSD2016-3, complete sequence	66575-66599	5	0.8
NC_011852_1	1.5\|225547\|31\|NC_011852\|CRISPRCasFinder	225547-225577	31	MK448705	Streptococcus phage Javan215, complete genome	33643-33673	6	0.806
NC_011852_1	1.6\|225610\|31\|NC_011852\|CRISPRCasFinder	225610-225640	31	MK448705	Streptococcus phage Javan215, complete genome	33643-33673	6	0.806
NC_011852_3	3.2\|576698\|28\|NC_011852\|CRISPRCasFinder	576698-576725	28	NZ_CP015507	Bacillus oceanisediminis 2691 plasmid pBO1, complete sequence	213313-213340	6	0.786
NC_011852_3	3.2\|576698\|28\|NC_011852\|CRISPRCasFinder	576698-576725	28	MN693877	Marine virus AFVG_250M566, complete genome	12531-12558	6	0.786
NC_011852_3	3.2\|576698\|28\|NC_011852\|CRISPRCasFinder	576698-576725	28	NZ_LR735438	Staphylococcus epidermidis strain none isolate Se_BPH0723 plasmid 2	29509-29536	6	0.786
NC_011852_3	3.2\|576698\|28\|NC_011852\|CRISPRCasFinder	576698-576725	28	NZ_CP035293	Staphylococcus haemolyticus strain ATCC 29970 plasmid unnamed2, complete sequence	15871-15898	6	0.786
NC_011852_3	3.2\|576698\|28\|NC_011852\|CRISPRCasFinder	576698-576725	28	NZ_CP054005	Staphylococcus hominis strain FDAARGOS_762 plasmid unnamed1, complete sequence	1983-2010	6	0.786
NC_011852_3	3.2\|576698\|28\|NC_011852\|CRISPRCasFinder	576698-576725	28	NZ_CP051648	Staphylococcus caprae strain SY333 plasmid pSY333-45, complete sequence	33888-33915	6	0.786
NC_011852_3	3.2\|576698\|28\|NC_011852\|CRISPRCasFinder	576698-576725	28	NZ_AP017321	Staphylococcus aureus strain MI plasmid pMI, complete sequence	7414-7441	6	0.786
NC_011852_3	3.2\|576698\|28\|NC_011852\|CRISPRCasFinder	576698-576725	28	NZ_CP054578	Staphylococcus saprophyticus strain UTI-050 plasmid pUTI-050-3, complete sequence	11705-11732	6	0.786
NC_011852_3	3.2\|576698\|28\|NC_011852\|CRISPRCasFinder	576698-576725	28	NC_013372	Staphylococcus epidermidis plasmid SAP016A, complete sequence	7307-7334	6	0.786
NC_011852_3	3.2\|576698\|28\|NC_011852\|CRISPRCasFinder	576698-576725	28	NC_009619	Staphylococcus aureus subsp. aureus JH1 plasmid pSJH101, complete sequence	14202-14229	6	0.786
NC_011852_3	3.2\|576698\|28\|NC_011852\|CRISPRCasFinder	576698-576725	28	NC_009477	Staphylococcus aureus subsp. aureus JH9 plasmid pSJH901, complete sequence	29011-29038	6	0.786
NC_011852_3	3.2\|576698\|28\|NC_011852\|CRISPRCasFinder	576698-576725	28	NZ_CP030325	Staphylococcus aureus strain AR_474 plasmid unnamed1, complete sequence	10957-10984	6	0.786
NC_011852_3	3.2\|576698\|28\|NC_011852\|CRISPRCasFinder	576698-576725	28	CP003674	Staphylococcus warneri SG1 plasmid clone pvSw5 genomic sequence	11996-12023	6	0.786
NC_011852_3	3.2\|576698\|28\|NC_011852\|CRISPRCasFinder	576698-576725	28	CP030497	Staphylococcus aureus strain ER02658.3 plasmid unnamed1, complete sequence	44693-44720	6	0.786
NC_011852_3	3.2\|576698\|28\|NC_011852\|CRISPRCasFinder	576698-576725	28	NZ_CP027419	Staphylococcus cohnii strain FDAARGOS_334 plasmid unnamed2, complete sequence	30640-30667	6	0.786
NC_011852_3	3.2\|576698\|28\|NC_011852\|CRISPRCasFinder	576698-576725	28	NC_013338	Staphylococcus aureus plasmid SAP068A, complete sequence	26082-26109	6	0.786
NC_011852_3	3.2\|576698\|28\|NC_011852\|CRISPRCasFinder	576698-576725	28	NZ_CP031278	Staphylococcus hominis strain 19A plasmid unnamed1, complete sequence	6298-6325	6	0.786
NC_011852_3	3.2\|576698\|28\|NC_011852\|CRISPRCasFinder	576698-576725	28	NZ_CP016854	Staphylococcus aureus subsp. aureus strain 5118.N plasmid p5118.Nb, complete sequence	46669-46696	6	0.786
NC_011852_3	3.2\|576698\|28\|NC_011852\|CRISPRCasFinder	576698-576725	28	NZ_CP014130	Staphylococcus epidermidis strain FDAARGOS_161 plasmid unnamed1, complete sequence	20582-20609	6	0.786
NC_011852_1	1.5\|225547\|31\|NC_011852\|CRISPRCasFinder	225547-225577	31	CP029253	Streptococcus phage VS-2018a, complete genome	32659-32689	7	0.774
NC_011852_1	1.5\|225547\|31\|NC_011852\|CRISPRCasFinder	225547-225577	31	KY705287	Streptococcus phage P9854, complete genome	17429-17459	7	0.774
NC_011852_1	1.5\|225547\|31\|NC_011852\|CRISPRCasFinder	225547-225577	31	KY705287	Streptococcus phage P9854, complete genome	18851-18881	7	0.774
NC_011852_1	1.5\|225547\|31\|NC_011852\|CRISPRCasFinder	225547-225577	31	KY705284	Streptococcus phage P9851, complete genome	16306-16336	7	0.774
NC_011852_1	1.5\|225547\|31\|NC_011852\|CRISPRCasFinder	225547-225577	31	KY705286	Streptococcus phage P9853, complete genome	17166-17196	7	0.774
NC_011852_1	1.5\|225547\|31\|NC_011852\|CRISPRCasFinder	225547-225577	31	KY705286	Streptococcus phage P9853, complete genome	18069-18099	7	0.774
NC_011852_1	1.5\|225547\|31\|NC_011852\|CRISPRCasFinder	225547-225577	31	MT774376	CrAssphage cr55_1, complete genome	95725-95755	7	0.774
NC_011852_1	1.5\|225547\|31\|NC_011852\|CRISPRCasFinder	225547-225577	31	MT774380	CrAssphage cr1_1, complete genome	99826-99856	7	0.774
NC_011852_1	1.6\|225610\|31\|NC_011852\|CRISPRCasFinder	225610-225640	31	CP029253	Streptococcus phage VS-2018a, complete genome	32659-32689	7	0.774
NC_011852_1	1.6\|225610\|31\|NC_011852\|CRISPRCasFinder	225610-225640	31	KY705287	Streptococcus phage P9854, complete genome	17429-17459	7	0.774
NC_011852_1	1.6\|225610\|31\|NC_011852\|CRISPRCasFinder	225610-225640	31	KY705287	Streptococcus phage P9854, complete genome	18851-18881	7	0.774
NC_011852_1	1.6\|225610\|31\|NC_011852\|CRISPRCasFinder	225610-225640	31	KY705284	Streptococcus phage P9851, complete genome	16306-16336	7	0.774
NC_011852_1	1.6\|225610\|31\|NC_011852\|CRISPRCasFinder	225610-225640	31	KY705286	Streptococcus phage P9853, complete genome	17166-17196	7	0.774
NC_011852_1	1.6\|225610\|31\|NC_011852\|CRISPRCasFinder	225610-225640	31	KY705286	Streptococcus phage P9853, complete genome	18069-18099	7	0.774
NC_011852_1	1.6\|225610\|31\|NC_011852\|CRISPRCasFinder	225610-225640	31	MT774376	CrAssphage cr55_1, complete genome	95725-95755	7	0.774
NC_011852_1	1.6\|225610\|31\|NC_011852\|CRISPRCasFinder	225610-225640	31	MT774380	CrAssphage cr1_1, complete genome	99826-99856	7	0.774
NC_011852_1	1.5\|225547\|31\|NC_011852\|CRISPRCasFinder	225547-225577	31	MT774380	CrAssphage cr1_1, complete genome	22-52	8	0.742
NC_011852_1	1.5\|225547\|31\|NC_011852\|CRISPRCasFinder	225547-225577	31	MT774380	CrAssphage cr1_1, complete genome	99853-99882	8	0.742
NC_011852_1	1.5\|225547\|31\|NC_011852\|CRISPRCasFinder	225547-225577	31	MK448940	Streptococcus phage Javan444, complete genome	30426-30456	8	0.742
NC_011852_1	1.5\|225547\|31\|NC_011852\|CRISPRCasFinder	225547-225577	31	MK448915	Streptococcus phage Javan350, complete genome	32482-32512	8	0.742
NC_011852_1	1.6\|225610\|31\|NC_011852\|CRISPRCasFinder	225610-225640	31	MT774380	CrAssphage cr1_1, complete genome	22-52	8	0.742
NC_011852_1	1.6\|225610\|31\|NC_011852\|CRISPRCasFinder	225610-225640	31	MT774380	CrAssphage cr1_1, complete genome	99853-99882	8	0.742
NC_011852_1	1.6\|225610\|31\|NC_011852\|CRISPRCasFinder	225610-225640	31	MK448940	Streptococcus phage Javan444, complete genome	30426-30456	8	0.742
NC_011852_1	1.6\|225610\|31\|NC_011852\|CRISPRCasFinder	225610-225640	31	MK448915	Streptococcus phage Javan350, complete genome	32482-32512	8	0.742
NC_011852_1	1.5\|225547\|31\|NC_011852\|CRISPRCasFinder	225547-225577	31	MK448980	Streptococcus phage Javan536, complete genome	33807-33837	9	0.71
NC_011852_1	1.5\|225547\|31\|NC_011852\|CRISPRCasFinder	225547-225577	31	MK448874	Streptococcus phage Javan206, complete genome	31674-31704	9	0.71
NC_011852_1	1.6\|225610\|31\|NC_011852\|CRISPRCasFinder	225610-225640	31	MK448980	Streptococcus phage Javan536, complete genome	33807-33837	9	0.71
NC_011852_1	1.6\|225610\|31\|NC_011852\|CRISPRCasFinder	225610-225640	31	MK448874	Streptococcus phage Javan206, complete genome	31674-31704	9	0.71
NC_011852_1	1.5\|225547\|31\|NC_011852\|CRISPRCasFinder	225547-225577	31	MT774380	CrAssphage cr1_1, complete genome	1-25	10	0.677
NC_011852_1	1.6\|225610\|31\|NC_011852\|CRISPRCasFinder	225610-225640	31	MT774380	CrAssphage cr1_1, complete genome	1-25	10	0.677

1. spacer 1.9|225781|22|NC_011852|CRISPRCasFinder matches to MN585984 (Mycobacterium phage AgronaGT15, complete genome) position: , mismatch: 2, identity: 0.909

accacaaggacctacgggtcca	CRISPR spacer
tccacagggacctacgggtcca	Protospacer
 *****.***************

2. spacer 3.1|576650|25|NC_011852|CRISPRCasFinder matches to NZ_CP034302 (Vibrio parahaemolyticus strain 20160303005-1 plasmid pVPSD2016-3, complete sequence) position: , mismatch: 5, identity: 0.8

atcatcagatttcatcattccatcc	CRISPR spacer
gttatcagatttcatcattccaata	Protospacer
.*.******************* .

3. spacer 1.5|225547|31|NC_011852|CRISPRCasFinder matches to MK448705 (Streptococcus phage Javan215, complete genome) position: , mismatch: 6, identity: 0.806

tgaaccgggtcctaaaggtgaacaaggtatt	CRISPR spacer
tattcagggtcctaaaggtgaccaaggtatc	Protospacer
*.  * *************** ********.

4. spacer 1.6|225610|31|NC_011852|CRISPRCasFinder matches to MK448705 (Streptococcus phage Javan215, complete genome) position: , mismatch: 6, identity: 0.806

tgaaccgggtcctaaaggtgaacaaggtatt	CRISPR spacer
tattcagggtcctaaaggtgaccaaggtatc	Protospacer
*.  * *************** ********.

5. spacer 3.2|576698|28|NC_011852|CRISPRCasFinder matches to NZ_CP015507 (Bacillus oceanisediminis 2691 plasmid pBO1, complete sequence) position: , mismatch: 6, identity: 0.786

catatgatcttttttcatatcatcagat	CRISPR spacer
gttatgatctttattcatattatcagcc	Protospacer
  ********** *******.***** .

6. spacer 3.2|576698|28|NC_011852|CRISPRCasFinder matches to MN693877 (Marine virus AFVG_250M566, complete genome) position: , mismatch: 6, identity: 0.786

catatgatcttttttcatatcatcagat	CRISPR spacer
catatgatctttattcataacatctatg	Protospacer
************ ****** **** .

7. spacer 3.2|576698|28|NC_011852|CRISPRCasFinder matches to NZ_LR735438 (Staphylococcus epidermidis strain none isolate Se_BPH0723 plasmid 2) position: , mismatch: 6, identity: 0.786

catatgatcttttttcatatcatcagat	CRISPR spacer
ttcaagatcttttttcatatcttcaaat	Protospacer
. .* **************** ***.**

8. spacer 3.2|576698|28|NC_011852|CRISPRCasFinder matches to NZ_CP035293 (Staphylococcus haemolyticus strain ATCC 29970 plasmid unnamed2, complete sequence) position: , mismatch: 6, identity: 0.786

catatgatcttttttcatatcatcagat	CRISPR spacer
ttcaagatcttttttcatatcttcaaat	Protospacer
. .* **************** ***.**

9. spacer 3.2|576698|28|NC_011852|CRISPRCasFinder matches to NZ_CP054005 (Staphylococcus hominis strain FDAARGOS_762 plasmid unnamed1, complete sequence) position: , mismatch: 6, identity: 0.786

catatgatcttttttcatatcatcagat	CRISPR spacer
ttcaagatcttttttcatatcttcaaat	Protospacer
. .* **************** ***.**

10. spacer 3.2|576698|28|NC_011852|CRISPRCasFinder matches to NZ_CP051648 (Staphylococcus caprae strain SY333 plasmid pSY333-45, complete sequence) position: , mismatch: 6, identity: 0.786

catatgatcttttttcatatcatcagat	CRISPR spacer
ttcaagatcttttttcatatcttcaaat	Protospacer
. .* **************** ***.**

11. spacer 3.2|576698|28|NC_011852|CRISPRCasFinder matches to NZ_AP017321 (Staphylococcus aureus strain MI plasmid pMI, complete sequence) position: , mismatch: 6, identity: 0.786

catatgatcttttttcatatcatcagat	CRISPR spacer
ttcaagatcttttttcatatcttcaaat	Protospacer
. .* **************** ***.**

12. spacer 3.2|576698|28|NC_011852|CRISPRCasFinder matches to NZ_CP054578 (Staphylococcus saprophyticus strain UTI-050 plasmid pUTI-050-3, complete sequence) position: , mismatch: 6, identity: 0.786

catatgatcttttttcatatcatcagat	CRISPR spacer
ttcaagatcttttttcatatcttcaaat	Protospacer
. .* **************** ***.**

13. spacer 3.2|576698|28|NC_011852|CRISPRCasFinder matches to NC_013372 (Staphylococcus epidermidis plasmid SAP016A, complete sequence) position: , mismatch: 6, identity: 0.786

catatgatcttttttcatatcatcagat	CRISPR spacer
ttcaagatcttttttcatatcttcaaat	Protospacer
. .* **************** ***.**

14. spacer 3.2|576698|28|NC_011852|CRISPRCasFinder matches to NC_009619 (Staphylococcus aureus subsp. aureus JH1 plasmid pSJH101, complete sequence) position: , mismatch: 6, identity: 0.786

catatgatcttttttcatatcatcagat	CRISPR spacer
ttcaagatcttttttcatatcttcaaat	Protospacer
. .* **************** ***.**

15. spacer 3.2|576698|28|NC_011852|CRISPRCasFinder matches to NC_009477 (Staphylococcus aureus subsp. aureus JH9 plasmid pSJH901, complete sequence) position: , mismatch: 6, identity: 0.786

catatgatcttttttcatatcatcagat	CRISPR spacer
ttcaagatcttttttcatatcttcaaat	Protospacer
. .* **************** ***.**

16. spacer 3.2|576698|28|NC_011852|CRISPRCasFinder matches to NZ_CP030325 (Staphylococcus aureus strain AR_474 plasmid unnamed1, complete sequence) position: , mismatch: 6, identity: 0.786

catatgatcttttttcatatcatcagat	CRISPR spacer
ttcaagatcttttttcatatcttcaaat	Protospacer
. .* **************** ***.**

17. spacer 3.2|576698|28|NC_011852|CRISPRCasFinder matches to CP003674 (Staphylococcus warneri SG1 plasmid clone pvSw5 genomic sequence) position: , mismatch: 6, identity: 0.786

catatgatcttttttcatatcatcagat	CRISPR spacer
ttcaagatcttttttcatatcttcaaat	Protospacer
. .* **************** ***.**

18. spacer 3.2|576698|28|NC_011852|CRISPRCasFinder matches to CP030497 (Staphylococcus aureus strain ER02658.3 plasmid unnamed1, complete sequence) position: , mismatch: 6, identity: 0.786

catatgatcttttttcatatcatcagat	CRISPR spacer
ttcaagatcttttttcatatcttcaaat	Protospacer
. .* **************** ***.**

19. spacer 3.2|576698|28|NC_011852|CRISPRCasFinder matches to NZ_CP027419 (Staphylococcus cohnii strain FDAARGOS_334 plasmid unnamed2, complete sequence) position: , mismatch: 6, identity: 0.786

catatgatcttttttcatatcatcagat	CRISPR spacer
ttcaagatcttttttcatatcttcaaat	Protospacer
. .* **************** ***.**

20. spacer 3.2|576698|28|NC_011852|CRISPRCasFinder matches to NC_013338 (Staphylococcus aureus plasmid SAP068A, complete sequence) position: , mismatch: 6, identity: 0.786

catatgatcttttttcatatcatcagat	CRISPR spacer
ttcaagatcttttttcatatcttcaaat	Protospacer
. .* **************** ***.**

21. spacer 3.2|576698|28|NC_011852|CRISPRCasFinder matches to NZ_CP031278 (Staphylococcus hominis strain 19A plasmid unnamed1, complete sequence) position: , mismatch: 6, identity: 0.786

catatgatcttttttcatatcatcagat	CRISPR spacer
ttcaagatcttttttcatatcttcaaat	Protospacer
. .* **************** ***.**

22. spacer 3.2|576698|28|NC_011852|CRISPRCasFinder matches to NZ_CP016854 (Staphylococcus aureus subsp. aureus strain 5118.N plasmid p5118.Nb, complete sequence) position: , mismatch: 6, identity: 0.786

catatgatcttttttcatatcatcagat	CRISPR spacer
ttcaagatcttttttcatatcttcaaat	Protospacer
. .* **************** ***.**

23. spacer 3.2|576698|28|NC_011852|CRISPRCasFinder matches to NZ_CP014130 (Staphylococcus epidermidis strain FDAARGOS_161 plasmid unnamed1, complete sequence) position: , mismatch: 6, identity: 0.786

catatgatcttttttcatatcatcagat	CRISPR spacer
ttcaagatcttttttcatatcttcaaat	Protospacer
. .* **************** ***.**

24. spacer 1.5|225547|31|NC_011852|CRISPRCasFinder matches to CP029253 (Streptococcus phage VS-2018a, complete genome) position: , mismatch: 7, identity: 0.774

tgaaccgggtcctaaaggtgaacaaggtatt	CRISPR spacer
accacaaggtcctaaaggtgaccaaggtata	Protospacer
   ** .************** ********

25. spacer 1.5|225547|31|NC_011852|CRISPRCasFinder matches to KY705287 (Streptococcus phage P9854, complete genome) position: , mismatch: 7, identity: 0.774

tgaaccgggtcctaaaggtgaacaaggtatt	CRISPR spacer
accacaaggtcctaaaggtgaccaaggtata	Protospacer
   ** .************** ********

26. spacer 1.5|225547|31|NC_011852|CRISPRCasFinder matches to KY705287 (Streptococcus phage P9854, complete genome) position: , mismatch: 7, identity: 0.774

tgaaccgggtcctaaaggtgaacaaggtatt	CRISPR spacer
accacaaggtcctaaaggtgaccaaggtata	Protospacer
   ** .************** ********

27. spacer 1.5|225547|31|NC_011852|CRISPRCasFinder matches to KY705284 (Streptococcus phage P9851, complete genome) position: , mismatch: 7, identity: 0.774

tgaaccgggtcctaaaggtgaacaaggtatt	CRISPR spacer
accacaaggtcctaaaggtgaccaaggtata	Protospacer
   ** .************** ********

28. spacer 1.5|225547|31|NC_011852|CRISPRCasFinder matches to KY705286 (Streptococcus phage P9853, complete genome) position: , mismatch: 7, identity: 0.774

tgaaccgggtcctaaaggtgaacaaggtatt	CRISPR spacer
accacaaggtcctaaaggtgaccaaggtata	Protospacer
   ** .************** ********

29. spacer 1.5|225547|31|NC_011852|CRISPRCasFinder matches to KY705286 (Streptococcus phage P9853, complete genome) position: , mismatch: 7, identity: 0.774

tgaaccgggtcctaaaggtgaacaaggtatt	CRISPR spacer
accacaaggtcctaaaggtgaccaaggtata	Protospacer
   ** .************** ********

30. spacer 1.5|225547|31|NC_011852|CRISPRCasFinder matches to MT774376 (CrAssphage cr55_1, complete genome) position: , mismatch: 7, identity: 0.774

tgaaccgggtcctaaaggtgaacaaggtatt	CRISPR spacer
ggaacctggtcctaaaggtgaaccgggagct	Protospacer
 ***** **************** .** ..*

31. spacer 1.5|225547|31|NC_011852|CRISPRCasFinder matches to MT774380 (CrAssphage cr1_1, complete genome) position: , mismatch: 7, identity: 0.774

tgaaccgggtcctaaaggtgaacaaggtatt	CRISPR spacer
agaacctggtcctaaaggtgaaccgggagct	Protospacer
 ***** **************** .** ..*

32. spacer 1.6|225610|31|NC_011852|CRISPRCasFinder matches to CP029253 (Streptococcus phage VS-2018a, complete genome) position: , mismatch: 7, identity: 0.774

tgaaccgggtcctaaaggtgaacaaggtatt	CRISPR spacer
accacaaggtcctaaaggtgaccaaggtata	Protospacer
   ** .************** ********

33. spacer 1.6|225610|31|NC_011852|CRISPRCasFinder matches to KY705287 (Streptococcus phage P9854, complete genome) position: , mismatch: 7, identity: 0.774

tgaaccgggtcctaaaggtgaacaaggtatt	CRISPR spacer
accacaaggtcctaaaggtgaccaaggtata	Protospacer
   ** .************** ********

34. spacer 1.6|225610|31|NC_011852|CRISPRCasFinder matches to KY705287 (Streptococcus phage P9854, complete genome) position: , mismatch: 7, identity: 0.774

tgaaccgggtcctaaaggtgaacaaggtatt	CRISPR spacer
accacaaggtcctaaaggtgaccaaggtata	Protospacer
   ** .************** ********

35. spacer 1.6|225610|31|NC_011852|CRISPRCasFinder matches to KY705284 (Streptococcus phage P9851, complete genome) position: , mismatch: 7, identity: 0.774

tgaaccgggtcctaaaggtgaacaaggtatt	CRISPR spacer
accacaaggtcctaaaggtgaccaaggtata	Protospacer
   ** .************** ********

36. spacer 1.6|225610|31|NC_011852|CRISPRCasFinder matches to KY705286 (Streptococcus phage P9853, complete genome) position: , mismatch: 7, identity: 0.774

tgaaccgggtcctaaaggtgaacaaggtatt	CRISPR spacer
accacaaggtcctaaaggtgaccaaggtata	Protospacer
   ** .************** ********

37. spacer 1.6|225610|31|NC_011852|CRISPRCasFinder matches to KY705286 (Streptococcus phage P9853, complete genome) position: , mismatch: 7, identity: 0.774

tgaaccgggtcctaaaggtgaacaaggtatt	CRISPR spacer
accacaaggtcctaaaggtgaccaaggtata	Protospacer
   ** .************** ********

38. spacer 1.6|225610|31|NC_011852|CRISPRCasFinder matches to MT774376 (CrAssphage cr55_1, complete genome) position: , mismatch: 7, identity: 0.774

tgaaccgggtcctaaaggtgaacaaggtatt	CRISPR spacer
ggaacctggtcctaaaggtgaaccgggagct	Protospacer
 ***** **************** .** ..*

39. spacer 1.6|225610|31|NC_011852|CRISPRCasFinder matches to MT774380 (CrAssphage cr1_1, complete genome) position: , mismatch: 7, identity: 0.774

tgaaccgggtcctaaaggtgaacaaggtatt	CRISPR spacer
agaacctggtcctaaaggtgaaccgggagct	Protospacer
 ***** **************** .** ..*

40. spacer 1.5|225547|31|NC_011852|CRISPRCasFinder matches to MT774380 (CrAssphage cr1_1, complete genome) position: , mismatch: 8, identity: 0.742

tgaaccgggtcctaaaggtgaacaaggtatt	CRISPR spacer
agaacctggtcctaaaggtgaaccgggagaa	Protospacer
 ***** **************** .** .

41. spacer 1.5|225547|31|NC_011852|CRISPRCasFinder matches to MT774380 (CrAssphage cr1_1, complete genome) position: , mismatch: 8, identity: 0.742

tgaaccgggtcctaaaggtgaacaaggtatt	CRISPR spacer
-gaacctggtcctaaaggtgaaccgggagaa	Protospacer
 ***** **************** .** .

42. spacer 1.5|225547|31|NC_011852|CRISPRCasFinder matches to MK448940 (Streptococcus phage Javan444, complete genome) position: , mismatch: 8, identity: 0.742

tgaaccgggtcctaaaggtgaacaaggtatt	CRISPR spacer
tattcaaggtcccaaaggtgaccaaggtatc	Protospacer
*.  * .*****.******** ********.

43. spacer 1.5|225547|31|NC_011852|CRISPRCasFinder matches to MK448915 (Streptococcus phage Javan350, complete genome) position: , mismatch: 8, identity: 0.742

tgaaccgggtcctaaaggtgaacaaggtatt	CRISPR spacer
tttgcaaggtcccaaaggtgaccaaggtatc	Protospacer
*  .* .*****.******** ********.

44. spacer 1.6|225610|31|NC_011852|CRISPRCasFinder matches to MT774380 (CrAssphage cr1_1, complete genome) position: , mismatch: 8, identity: 0.742

tgaaccgggtcctaaaggtgaacaaggtatt	CRISPR spacer
agaacctggtcctaaaggtgaaccgggagaa	Protospacer
 ***** **************** .** .

45. spacer 1.6|225610|31|NC_011852|CRISPRCasFinder matches to MT774380 (CrAssphage cr1_1, complete genome) position: , mismatch: 8, identity: 0.742

tgaaccgggtcctaaaggtgaacaaggtatt	CRISPR spacer
-gaacctggtcctaaaggtgaaccgggagaa	Protospacer
 ***** **************** .** .

46. spacer 1.6|225610|31|NC_011852|CRISPRCasFinder matches to MK448940 (Streptococcus phage Javan444, complete genome) position: , mismatch: 8, identity: 0.742

tgaaccgggtcctaaaggtgaacaaggtatt	CRISPR spacer
tattcaaggtcccaaaggtgaccaaggtatc	Protospacer
*.  * .*****.******** ********.

47. spacer 1.6|225610|31|NC_011852|CRISPRCasFinder matches to MK448915 (Streptococcus phage Javan350, complete genome) position: , mismatch: 8, identity: 0.742

tgaaccgggtcctaaaggtgaacaaggtatt	CRISPR spacer
tttgcaaggtcccaaaggtgaccaaggtatc	Protospacer
*  .* .*****.******** ********.

48. spacer 1.5|225547|31|NC_011852|CRISPRCasFinder matches to MK448980 (Streptococcus phage Javan536, complete genome) position: , mismatch: 9, identity: 0.71

tgaaccgggtcctaaaggtgaacaaggtatt	CRISPR spacer
cttgcaaggtccaaaaggtgaccaaggtatc	Protospacer
.  .* .***** ******** ********.

49. spacer 1.5|225547|31|NC_011852|CRISPRCasFinder matches to MK448874 (Streptococcus phage Javan206, complete genome) position: , mismatch: 9, identity: 0.71

tgaaccgggtcctaaaggtgaacaaggtatt	CRISPR spacer
cttgcaaggtcccaaaggtgaccaaggtatc	Protospacer
.  .* .*****.******** ********.

50. spacer 1.6|225610|31|NC_011852|CRISPRCasFinder matches to MK448980 (Streptococcus phage Javan536, complete genome) position: , mismatch: 9, identity: 0.71

tgaaccgggtcctaaaggtgaacaaggtatt	CRISPR spacer
cttgcaaggtccaaaaggtgaccaaggtatc	Protospacer
.  .* .***** ******** ********.

51. spacer 1.6|225610|31|NC_011852|CRISPRCasFinder matches to MK448874 (Streptococcus phage Javan206, complete genome) position: , mismatch: 9, identity: 0.71

tgaaccgggtcctaaaggtgaacaaggtatt	CRISPR spacer
cttgcaaggtcccaaaggtgaccaaggtatc	Protospacer
.  .* .*****.******** ********.

52. spacer 1.5|225547|31|NC_011852|CRISPRCasFinder matches to MT774380 (CrAssphage cr1_1, complete genome) position: , mismatch: 10, identity: 0.677

tgaaccgggtcctaaaggtgaacaaggtatt	CRISPR spacer
agaacctggtcctaaaggtgaaccg------	Protospacer
 ***** **************** .

53. spacer 1.6|225610|31|NC_011852|CRISPRCasFinder matches to MT774380 (CrAssphage cr1_1, complete genome) position: , mismatch: 10, identity: 0.677

tgaaccgggtcctaaaggtgaacaaggtatt	CRISPR spacer
agaacctggtcctaaaggtgaaccg------	Protospacer
 ***** **************** .

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

401165 : 465902

Mannheimia_phage(32.14%)

protease,transposase,integrase,tail

attL 411656:411674|attR 467356:467374

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_005714908.1\|401165_402152_-\|transposase	IS110 family transposase	Q75QL1	Wolbachia_phage	9.7e-22	32.7
WP_012621698.1\|402603_403590_+	o-succinylbenzoate synthase	NA	NA	NA	NA
WP_049753180.1\|403851_407841_+	YadA-like family protein	A0A2C9CZB7	Yersinia_phage	1.6e-06	42.5
WP_041603108.1\|407951_408203_-	hypothetical protein	NA	NA	NA	NA
WP_005714445.1\|408168_408552_-	YacL family protein	NA	NA	NA	NA
WP_012621699.1\|408636_411465_-	excinuclease ABC subunit UvrA	A0A1B1IVR3	uncultured_Mediterranean_phage	2.5e-304	55.7
411656:411674	attL	NA	NA	NA	NA
WP_012621700.1\|411723_412242_+	single-stranded DNA-binding protein	I3PGW4	Xanthomonas_phage	6.4e-41	55.2
WP_012621701.1\|412449_413664_+	ATP-binding protein	NA	NA	NA	NA
WP_012621702.1\|414053_415274_-	ATP-dependent RNA helicase RhlB	E3T5E1	Cafeteria_roenbergensis_virus	3.3e-40	31.1
WP_005712616.1\|415337_415610_-	HigA family addiction module antidote protein	A0A2P1MXE5	Escherichia_phage	2.2e-08	42.5
WP_012621703.1\|415620_415899_-	type II toxin-antitoxin system RelE/ParE family toxin	A0A0M3LQB1	Mannheimia_phage	2.6e-17	48.9
WP_005712612.1\|416047_417058_+	ornithine carbamoyltransferase	NA	NA	NA	NA
WP_012621704.1\|417404_418667_+	serine hydroxymethyltransferase	A0A240F3L3	Aeromonas_phage	4.3e-99	53.0
WP_012621705.1\|418780_420109_+	exodeoxyribonuclease VII large subunit	A0A1V0SD82	Indivirus	1.3e-42	39.1
WP_041603109.1\|420142_422386_-	DNA topoisomerase IV subunit A	G3M9Z5	Bacillus_virus	1.7e-85	35.5
WP_010786773.1\|422481_422847_+	hypothetical protein	NA	NA	NA	NA
WP_012621707.1\|422999_423782_-	alpha/beta fold hydrolase	NA	NA	NA	NA
WP_010786771.1\|423889_424450_+	replication initiation negative regulator SeqA	NA	NA	NA	NA
WP_012621708.1\|424453_425869_+	o-succinylbenzoate--CoA ligase	NA	NA	NA	NA
WP_012621709.1\|425861_429155_+	mechanosensitive channel MscK	NA	NA	NA	NA
WP_005712594.1\|429280_430363_+	chorismate synthase	A0A291AU41	Pandoravirus	2.9e-88	47.4
WP_012621710.1\|430570_430846_+	type II toxin-antitoxin system RelE/ParE family toxin	A0A0M3LQB1	Mannheimia_phage	1.7e-37	71.4
WP_005712590.1\|430854_431151_+	HigA family addiction module antidote protein	A0A0M3LPV0	Mannheimia_phage	6.4e-38	80.2
WP_012621711.1\|431166_432372_-	ROK family protein	NA	NA	NA	NA
WP_012621712.1\|432546_433674_+	ribonuclease D	NA	NA	NA	NA
WP_012621713.1\|434122_435322_+	acetate kinase	NA	NA	NA	NA
WP_010786962.1\|435430_437566_+	phosphate acetyltransferase	NA	NA	NA	NA
WP_005712580.1\|437676_438636_-	ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_012621715.1\|438814_439222_-\|protease	ClpXP protease specificity-enhancing factor	A0A1S5R3H3	Pseudomonas_phage	8.9e-22	46.1
WP_005712577.1\|439223_439865_-	glutathione S-transferase N-terminal domain-containing protein	NA	NA	NA	NA
WP_005712575.1\|440080_440398_+	DUF496 family protein	NA	NA	NA	NA
WP_012621716.1\|440441_441740_-	bifunctional tetrahydrofolate synthase/dihydrofolate synthase	NA	NA	NA	NA
WP_012621717.1\|441739_442630_-	acetyl-CoA carboxylase, carboxyltransferase subunit beta	NA	NA	NA	NA
WP_035499902.1\|442717_443080_-	type II toxin-antitoxin system PemK/MazF family toxin	NA	NA	NA	NA
WP_005712567.1\|443073_443343_-	antitoxin	NA	NA	NA	NA
WP_005712565.1\|443593_444784_+	aspartate/tyrosine/aromatic aminotransferase	NA	NA	NA	NA
WP_010786955.1\|444864_445779_-	DMT family transporter	NA	NA	NA	NA
WP_041603110.1\|445850_447038_+	NAD(P)/FAD-dependent oxidoreductase	NA	NA	NA	NA
WP_005714470.1\|447101_447983_-	N-acetylneuraminate lyase	NA	NA	NA	NA
WP_012621719.1\|448064_448931_-	MurR/RpiR family transcriptional regulator	NA	NA	NA	NA
WP_012621720.1\|448932_449403_-	YhcH/YjgK/YiaL family protein	NA	NA	NA	NA
WP_005714476.1\|450580_450859_+	type II toxin-antitoxin system RelE/ParE family toxin	A0A0M3LQB1	Mannheimia_phage	4.0e-18	50.0
WP_005714478.1\|450870_451152_+	HigA family addiction module antidote protein	A0A2L1IV52	Escherichia_phage	2.3e-08	36.6
WP_012621721.1\|451148_451886_-\|tail	phage minor tail protein L	A0A0M3LSQ5	Mannheimia_phage	3.0e-68	54.1
WP_157858957.1\|451895_452384_-	hypothetical protein	A0A0M3LS69	Mannheimia_phage	2.3e-32	60.3
WP_010786945.1\|453223_454711_-	DUF4041 domain-containing protein	X5JAC1	Clostridium_phage	1.8e-56	48.4
WP_010786944.1\|454828_455176_-	hypothetical protein	NA	NA	NA	NA
WP_012621722.1\|455252_455579_-\|tail	phage tail protein	A0A0M3LQW6	Mannheimia_phage	1.4e-38	60.7
WP_010786942.1\|455580_455916_-	hypothetical protein	A0A0M3LQT0	Mannheimia_phage	1.4e-33	67.3
WP_041603113.1\|456968_457490_-	phage antirepressor N-terminal domain-containing protein	A0A0M3LR56	Mannheimia_phage	1.5e-34	53.5
WP_041603221.1\|457758_458472_-	recombinase	A0A0R6PHM5	Moraxella_phage	6.5e-44	44.3
WP_160427089.1\|458524_458827_-	hypothetical protein	NA	NA	NA	NA
WP_041603114.1\|459180_460044_-\|transposase	IS256 family transposase	A0A218MNI5	uncultured_virus	1.6e-49	48.1
WP_049753181.1\|460074_460716_-\|integrase	integrase arm-type DNA-binding domain-containing protein	A0A1V0E8G8	Vibrio_phage	1.2e-20	33.2
WP_005712907.1\|460999_461329_-	preprotein translocase subunit SecG	NA	NA	NA	NA
WP_012621725.1\|461454_463377_-	DNA topoisomerase III	A0A1X9I6W8	Streptococcus_phage	1.0e-35	28.9
WP_012621726.1\|463384_464209_-	penicillin-insensitive murein endopeptidase	NA	NA	NA	NA
WP_005712900.1\|464566_464965_-	DUF423 domain-containing protein	NA	NA	NA	NA
WP_020997002.1\|465041_465188_-	type II toxin-antitoxin system RelE/ParE family toxin	NA	NA	NA	NA
WP_005712896.1\|465227_465590_-	hypothetical protein	A0A222YXG1	Escherichia_phage	2.4e-34	61.5
WP_005712894.1\|465599_465902_-	type II toxin-antitoxin system HigB family toxin	F5A3A2	Riemerella_phage	2.3e-11	37.6
467356:467374	attR	NA	NA	NA	NA

DBSCAN-SWA_2

545040 : 644746

118

Mannheimia_phage(42.37%)

tail,protease,transposase,portal,terminase,holin,tRNA,capsid

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_012621762.1\|545040_547044_+\|tRNA	bifunctional tRNA (5-methylaminomethyl-2-thiouridine)(34)-methyltransferase MnmD/FAD-dependent 5-carboxymethylaminomethyl-2-thiouridine(34) oxidoreductase MnmC	NA	NA	NA	NA
WP_012621763.1\|547170_547941_-	Nif3-like dinuclear metal center hexameric protein	NA	NA	NA	NA
WP_012621764.1\|548330_549563_-	molybdopterin molybdotransferase MoeA	NA	NA	NA	NA
WP_012621529.1\|549820_550792_+\|transposase	IS110 family transposase	A0A1S7J231	Thermus_phage	4.1e-09	28.8
WP_012621765.1\|550860_551484_-	MarC family protein	NA	NA	NA	NA
WP_041603119.1\|553595_553844_-	hypothetical protein	NA	NA	NA	NA
WP_012621767.1\|553806_555735_-\|protease	ATP-dependent zinc metalloprotease FtsH	G9E4U6	Ostreococcus_lucimarinus_virus	1.2e-116	43.2
WP_010786866.1\|555808_556435_-	23S rRNA (uridine(2552)-2'-O)-methyltransferase RlmE	NA	NA	NA	NA
WP_012621768.1\|556677_557466_+	SDR family oxidoreductase	NA	NA	NA	NA
WP_012621769.1\|557545_558208_+	Fic family protein	NA	NA	NA	NA
WP_012621770.1\|558265_558562_-	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_005714197.1\|558564_558909_-	type II toxin-antitoxin system RelE/ParE family toxin	NA	NA	NA	NA
WP_012621771.1\|559123_561103_+	exoribonuclease II	NA	NA	NA	NA
WP_012621772.1\|561213_562305_+	murein transglycosylase A	NA	NA	NA	NA
WP_049753185.1\|563305_566839_-	YadA-like family protein	NA	NA	NA	NA
WP_005714340.1\|567451_568048_-	DedA family protein	NA	NA	NA	NA
WP_005714341.1\|568058_569081_-	HTH-type transcriptional repressor PurR	C6ZCU4	Enterobacteria_phage	1.2e-35	33.8
WP_010786764.1\|569194_570139_-	50S ribosomal protein L3 N(5)-glutamine methyltransferase	NA	NA	NA	NA
WP_005714346.1\|570225_570756_+	endonuclease SmrB	NA	NA	NA	NA
WP_010786763.1\|570897_572115_-	tyrosine transporter	NA	NA	NA	NA
WP_010786762.1\|572262_573477_-	amino acid permease	NA	NA	NA	NA
WP_010786761.1\|574272_574752_-	redoxin family protein	NA	NA	NA	NA
WP_010786760.1\|574769_575420_-	sulfite exporter TauE/SafE family protein	NA	NA	NA	NA
WP_012621776.1\|575421_576492_-	peptide-methionine (R)-S-oxide reductase MsrB	NA	NA	NA	NA
WP_010786758.1\|576595_576925_-	hypothetical protein	NA	NA	NA	NA
WP_005713976.1\|577066_577639_+	sigma-70 family RNA polymerase sigma factor	NA	NA	NA	NA
WP_005713975.1\|577635_577821_+	zf-HC2 domain-containing protein	NA	NA	NA	NA
WP_049753186.1\|578932_579229_-	helix-turn-helix domain-containing protein	A0A0M3LRV4	Mannheimia_phage	5.4e-21	59.8
WP_012621778.1\|579396_580212_+\|capsid	GPO family capsid scaffolding protein	A0A0M3LSA0	Mannheimia_phage	4.8e-51	44.1
WP_005713968.1\|580224_580428_+	hypothetical protein	NA	NA	NA	NA
WP_012621779.1\|580427_581081_+\|terminase	terminase	A4JWP8	Burkholderia_virus	2.9e-38	42.1
WP_010786754.1\|581115_581253_+	hypothetical protein	NA	NA	NA	NA
WP_005713963.1\|581236_581761_+	lysozyme	A0A0M3LQY4	Mannheimia_phage	7.6e-50	56.8
WP_012621780.1\|581745_582213_+	hypothetical protein	NA	NA	NA	NA
WP_012621781.1\|582395_582914_+	hypothetical protein	NA	NA	NA	NA
WP_012621782.1\|583119_583338_+	TraR/DksA family transcriptional regulator	A0A0M3LS11	Mannheimia_phage	1.6e-22	72.6
WP_012621783.1\|583334_583769_+\|tail	phage tail protein	Q19UR3	Mannheimia_phage	7.2e-38	54.9
WP_005713954.1\|583809_584271_+	phage virion morphogenesis protein	Q19UR2	Mannheimia_phage	1.0e-42	62.0
WP_041603121.1\|584591_587423_+\|tail	phage tail tape measure protein	V5YUN9	Pseudomonas_phage	5.5e-62	37.2
WP_010786746.1\|587549_588092_+	hypothetical protein	NA	NA	NA	NA
WP_010786745.1\|588084_588507_+	type II toxin-antitoxin system YafO family toxin	NA	NA	NA	NA
WP_173655637.1\|589603_590041_+	hypothetical protein	A0A0M3LS77	Mannheimia_phage	5.4e-41	59.7
WP_012621787.1\|590264_590450_+	type II toxin-antitoxin system HicA family toxin	NA	NA	NA	NA
WP_005714900.1\|590479_590917_+	type II toxin-antitoxin system HicB family antitoxin	A0A0R6PJ17	Moraxella_phage	1.4e-20	36.9
WP_012621788.1\|590938_591316_-	antitermination protein	Q7Y5V5	Haemophilus_phage	5.2e-08	28.7
WP_012621789.1\|591312_591882_-	recombination protein NinG	A0A0U4KL68	Pseudomonas_phage	1.6e-48	54.0
WP_041603231.1\|592026_592455_-	recombination protein NinB	Q7Y5V7	Haemophilus_phage	2.8e-42	58.6
WP_071610285.1\|592490_592688_-	hypothetical protein	A0A0M3LR43	Mannheimia_phage	1.0e-28	80.0
WP_012621791.1\|592710_593382_-\|holin	holin	D0UIL4	Aggregatibacter_phage	2.7e-39	37.7
WP_012621792.1\|593381_594212_-	hypothetical protein	A0A1X9SFR3	Acinetobacter_phage	1.4e-34	37.8
WP_012621793.1\|594208_594991_-	Rha family transcriptional regulator	A0A2D0YGX8	Vibrio_phage	6.1e-27	34.8
WP_012621794.1\|595270_595477_-	helix-turn-helix transcriptional regulator	A0A286S2C1	Klebsiella_phage	2.8e-08	45.3
WP_041603122.1\|595612_596266_+	helix-turn-helix domain-containing protein	A0A0M3LSL8	Mannheimia_phage	2.8e-70	69.5
WP_012621796.1\|596298_596733_+	hypothetical protein	NA	NA	NA	NA
WP_012621797.1\|596725_597202_+	hypothetical protein	NA	NA	NA	NA
WP_012621798.1\|597319_597502_+	type II toxin-antitoxin system HicA family toxin	A0A0M3LQ86	Mannheimia_phage	1.4e-06	50.0
WP_012621799.1\|597541_597961_+	type II toxin-antitoxin system HicB family antitoxin	A0A2H4JFV9	uncultured_Caudovirales_phage	2.1e-26	44.9
WP_041603123.1\|598293_598539_+	hypothetical protein	NA	NA	NA	NA
WP_012621801.1\|598816_599104_+	hypothetical protein	NA	NA	NA	NA
WP_012621802.1\|599130_599301_-	DUF1508 domain-containing protein	NA	NA	NA	NA
WP_012621803.1\|599315_599537_+	hypothetical protein	NA	NA	NA	NA
WP_012621805.1\|599878_600520_+	DUF3560 domain-containing protein	NA	NA	NA	NA
WP_075621039.1\|600473_600725_+	hypothetical protein	NA	NA	NA	NA
WP_012621807.1\|600729_601443_+	serine/threonine-protein phosphatase	I6PCV8	Cronobacter_phage	1.1e-51	45.1
WP_012621808.1\|601988_602309_+	hypothetical protein	NA	NA	NA	NA
WP_012621809.1\|602305_602845_+	hypothetical protein	A0A0M3LSK4	Mannheimia_phage	1.5e-24	47.3
WP_012621810.1\|602831_603038_+	hypothetical protein	NA	NA	NA	NA
WP_012621811.1\|603034_603973_+	recombinase RecT	A0A0M3LNU3	Mannheimia_phage	1.1e-139	82.1
WP_041603235.1\|604035_604695_+	translocation protein TolB precursor	A0A0M3LP90	Mannheimia_phage	1.6e-100	80.8
WP_012621813.1\|604694_605174_+	single-stranded DNA-binding protein	I3PGW4	Xanthomonas_phage	4.7e-38	53.5
WP_012621814.1\|605219_605408_-	hypothetical protein	Q19US2	Mannheimia_phage	2.6e-13	72.4
WP_012621815.1\|605754_606672_+	hypothetical protein	A0A0M3LPL3	Mannheimia_phage	3.6e-31	58.0
WP_012621816.1\|606695_606959_+	hypothetical protein	NA	NA	NA	NA
WP_012621817.1\|607102_607321_-	hypothetical protein	A0A0M3LQV3	Mannheimia_phage	5.2e-21	77.8
WP_012621818.1\|607747_608044_-	hypothetical protein	A0A0M3LR47	Mannheimia_phage	1.6e-17	48.0
WP_041603124.1\|608152_609187_-	hypothetical protein	NA	NA	NA	NA
WP_012621820.1\|609186_614070_-	DUF1983 domain-containing protein	A0A0M3LQ61	Mannheimia_phage	2.1e-290	38.2
WP_012621822.1\|615297_615483_-	hypothetical protein	NA	NA	NA	NA
WP_012621823.1\|615596_616115_-\|tail	tail assembly protein	A0A0M3LPS1	Mannheimia_phage	3.1e-35	50.3
WP_041603125.1\|616144_616909_-	C40 family peptidase	A0A0M3LQI5	Mannheimia_phage	1.1e-65	48.8
WP_010786326.1\|616898_617636_-\|tail	phage minor tail protein L	A0A0M3LSQ5	Mannheimia_phage	3.0e-68	54.1
WP_010786325.1\|617635_617968_-\|tail	phage tail protein	A5LH39	Enterobacteria_phage	2.1e-13	40.0
WP_012621825.1\|618012_621387_-\|tail	phage tail tape measure protein	A0A0E3JQ03	Enterobacteria_phage	1.9e-61	25.5
WP_005714514.1\|621442_621718_-	hypothetical protein	NA	NA	NA	NA
WP_010786323.1\|621919_622186_-	hypothetical protein	NA	NA	NA	NA
WP_010786322.1\|622269_622539_-	type II toxin-antitoxin system mRNA interferase toxin, RelE/StbE family	NA	NA	NA	NA
WP_005714576.1\|622542_622809_-	type II toxin-antitoxin system RelB/DinJ family antitoxin	NA	NA	NA	NA
WP_005714573.1\|622877_623105_-	DUF4035 domain-containing protein	NA	NA	NA	NA
WP_005714571.1\|623149_623551_-	hypothetical protein	NA	NA	NA	NA
WP_012621826.1\|623624_624290_-	hypothetical protein	NA	NA	NA	NA
WP_005714567.1\|624292_624712_-\|tail	phage tail protein	A0A291AWY2	Escherichia_phage	7.2e-11	33.3
WP_012621827.1\|624711_625245_-\|tail	phage tail protein	M9NZH5	Enterobacteria_phage	3.2e-19	35.3
WP_012621828.1\|625248_625551_-\|tail	phage tail protein	NA	NA	NA	NA
WP_012621829.1\|625543_625870_-	DUF2190 family protein	NA	NA	NA	NA
WP_010786317.1\|625937_627905_-\|protease	Clp protease ClpP	A0A1W6JT88	Pseudomonas_phage	6.1e-193	56.8
WP_010786316.1\|627929_629429_-\|portal	phage portal protein	K7PHM5	Enterobacterial_phage	2.9e-155	56.8
WP_005714374.1\|629429_629651_-	hypothetical protein	K7PMB5	Enterobacterial_phage	1.3e-11	55.9
WP_010786315.1\|629668_631789_-\|terminase	phage terminase large subunit family protein	A5LH27	Enterobacteria_phage	2.3e-270	66.7
WP_005714379.1\|631788_632256_-	DUF1441 family protein	K7PJY2	Enterobacterial_phage	1.3e-40	53.9
WP_041603127.1\|632749_633094_-	DUF2570 domain-containing protein	A0A0M3LSP1	Mannheimia_phage	3.7e-05	56.2
WP_012621833.1\|633066_633612_-	lysozyme	A0A0M3LPQ1	Mannheimia_phage	9.3e-43	48.7
WP_012621834.1\|633586_633862_-	hypothetical protein	A0A0M3LR95	Mannheimia_phage	1.4e-18	69.6
WP_012621835.1\|633975_634539_+	hypothetical protein	NA	NA	NA	NA
WP_005714781.1\|634830_635007_-	hypothetical protein	NA	NA	NA	NA
WP_012621837.1\|635303_635522_+	hypothetical protein	NA	NA	NA	NA
WP_012621788.1\|635530_635908_-	antitermination protein	Q7Y5V5	Haemophilus_phage	5.2e-08	28.7
WP_012621789.1\|635904_636474_-	recombination protein NinG	A0A0U4KL68	Pseudomonas_phage	1.6e-48	54.0
WP_041603231.1\|636618_637047_-	recombination protein NinB	Q7Y5V7	Haemophilus_phage	2.8e-42	58.6
WP_071610285.1\|637082_637280_-	hypothetical protein	A0A0M3LR43	Mannheimia_phage	1.0e-28	80.0
WP_012621791.1\|637302_637974_-\|holin	holin	D0UIL4	Aggregatibacter_phage	2.7e-39	37.7
WP_012621792.1\|637973_638804_-	hypothetical protein	A0A1X9SFR3	Acinetobacter_phage	1.4e-34	37.8
WP_012621838.1\|638800_639583_-	Rha family transcriptional regulator	A0A2D0YGX8	Vibrio_phage	1.0e-26	34.8
WP_010786732.1\|639862_640063_-	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_010786731.1\|640189_640861_+	helix-turn-helix transcriptional regulator	A0A1B1P9J5	Acinetobacter_phage	1.4e-19	29.8
WP_005714534.1\|640941_641790_+	KilA-N domain-containing protein	Q4ZC41	Staphylococcus_virus	2.8e-70	52.4
WP_010786730.1\|641923_643567_+	AAA family ATPase	NA	NA	NA	NA
WP_010786729.1\|643611_644427_+	DNA adenine methylase	NA	NA	NA	NA
WP_005714537.1\|644455_644746_-	putative addiction module antidote protein	A4JWV1	Burkholderia_virus	2.4e-13	46.6

DBSCAN-SWA_3

703798 : 713579

Ostreococcus_lucimarinus_virus(12.5%)

tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_012621868.1\|703798_705061_-	inorganic phosphate transporter	E5ES24	Ostreococcus_lucimarinus_virus	4.3e-59	35.5
WP_005714552.1\|705080_705761_-	TIGR00153 family protein	NA	NA	NA	NA
WP_012621869.1\|706070_707054_+\|tRNA	phenylalanine--tRNA ligase subunit alpha	A0A2H4UW22	Bodo_saltans_virus	7.1e-33	38.0
WP_012621870.1\|707226_709614_+\|tRNA	phenylalanine--tRNA ligase subunit beta	A0A1L3IZU3	BeAn_58058_virus	1.4e-05	29.9
WP_005710633.1\|709630_709927_+	integration host factor subunit alpha	A0A0H3UZA0	Geobacillus_virus	7.9e-12	38.9
WP_005710634.1\|709979_710492_+	C40 family peptidase	A0A0K2SUC1	Clostridium_phage	7.0e-16	39.1
WP_010786629.1\|710679_711333_+	uridine kinase	A0A1V0SAA3	Catovirus	1.1e-34	37.0
WP_005710639.1\|711349_711934_+	dCTP deaminase	I4AZP2	Saccharomonospora_phage	2.2e-29	40.5
WP_012621871.1\|712064_713579_-	amidophosphoribosyltransferase	A0A0M3SGR2	Mollivirus	4.1e-80	39.2

DBSCAN-SWA_4

824799 : 934828

115

Burkholderia_virus(14.89%)

plate,transposase,head,terminase,integrase,tRNA,tail

attL 853825:853843|attR 877273:877291

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_012621934.1\|824799_826017_-\|integrase	tyrosine-type recombinase/integrase	A0A1V0E8G8	Vibrio_phage	4.8e-79	39.5
WP_012621936.1\|827363_828008_+	orotate phosphoribosyltransferase	NA	NA	NA	NA
WP_005714322.1\|828461_829724_-	transcription termination factor Rho	NA	NA	NA	NA
WP_012621940.1\|830376_831246_+	Hsp33 family molecular chaperone HslO	NA	NA	NA	NA
WP_012621941.1\|831316_832087_+	DNA polymerase III subunit epsilon	A0A1X9SH08	Bradyrhizobium_phage	1.2e-35	37.7
WP_012621942.1\|832371_833826_-	decarboxylating NADP(+)-dependent phosphogluconate dehydrogenase	M4QQM4	Ostreococcus_lucimarinus_virus	9.5e-42	28.3
WP_012621943.1\|834163_834682_-\|transposase	transposase	NA	NA	NA	NA
WP_012621944.1\|834733_835093_-	DUF1304 domain-containing protein	NA	NA	NA	NA
WP_012621945.1\|835101_836121_-	DUF1016 family protein	NA	NA	NA	NA
WP_012621946.1\|836159_836858_-	6-phosphogluconolactonase	NA	NA	NA	NA
WP_005711691.1\|836973_838458_-	glucose-6-phosphate dehydrogenase	M4SIY3	Cyanophage	4.4e-87	38.8
WP_010787081.1\|838522_839335_-	3'(2'),5'-bisphosphate nucleotidase CysQ	NA	NA	NA	NA
WP_096334835.1\|839564_840662_+	peptide chain release factor 2	A0A0S4KWG0	Pseudomonas_phage	6.3e-06	42.4
WP_041603135.1\|840752_841715_-\|tRNA	tRNA 5-methoxyuridine(34)/uridine 5-oxyacetic acid(34) synthase CmoB	NA	NA	NA	NA
WP_012621948.1\|841837_842935_-\|transposase	ISAs1 family transposase	NA	NA	NA	NA
WP_010786294.1\|843619_843961_-	helix-hairpin-helix domain-containing protein	NA	NA	NA	NA
WP_012621949.1\|844218_845484_+	3-ketoacyl-ACP reductase	NA	NA	NA	NA
WP_005714011.1\|845543_845942_+	MliC family protein	NA	NA	NA	NA
WP_012621950.1\|845950_847003_+	lipopolysaccharide heptosyltransferase II	NA	NA	NA	NA
WP_005714008.1\|847098_847686_+	NAD(P)H-dependent oxidoreductase	NA	NA	NA	NA
WP_012621951.1\|847856_849515_+	phospho-sugar mutase	A0A1X9I671	Streptococcus_phage	1.3e-79	34.9
WP_005714004.1\|849645_850653_+	rRNA methyltransferase	NA	NA	NA	NA
WP_012621952.1\|850855_851839_+	octaprenyl diphosphate synthase	A0A1V0SE37	Indivirus	1.2e-08	23.7
WP_012621953.1\|852047_852788_+	epoxyqueuosine reductase QueH	NA	NA	NA	NA
WP_010786300.1\|852882_853818_+	ACP S-malonyltransferase	NA	NA	NA	NA
853825:853843	attL	NA	NA	NA	NA
WP_010786301.1\|853960_854686_+	3-oxoacyl-ACP reductase FabG	Q06VL0	Trichoplusia_ni_ascovirus	1.4e-14	31.4
WP_012621955.1\|854801_856088_+	branched-chain amino acid transport system II carrier protein	NA	NA	NA	NA
WP_005713993.1\|856144_856969_+	bifunctional DNA-formamidopyrimidine glycosylase/DNA-(apurinic or apyrimidinic site) lyase	G3MA33	Bacillus_virus	1.1e-31	33.0
WP_010787222.1\|857593_857962_-	transcriptional regulator	Q6QIE8	Burkholderia_phage	6.8e-21	43.0
WP_012621956.1\|857963_858362_-	regulatory protein GemA	A0A219VHC6	Ochrobactrum_phage	1.1e-05	30.2
WP_157858959.1\|858351_858528_-	hypothetical protein	NA	NA	NA	NA
WP_173655629.1\|858524_858686_-	hypothetical protein	NA	NA	NA	NA
WP_012621958.1\|858682_858895_-	ANR family transcriptional regulator	NA	NA	NA	NA
WP_012621959.1\|858891_859416_-	host-nuclease inhibitor Gam family protein	F6MIJ0	Haemophilus_phage	2.6e-42	51.7
WP_012621960.1\|859408_859627_-	hypothetical protein	NA	NA	NA	NA
WP_041603136.1\|859619_860792_-	AAA family ATPase	A4JWN1	Burkholderia_virus	3.3e-109	55.3
WP_041603137.1\|860816_862619_-\|integrase,transposase	DDE-type integrase/transposase/recombinase	J9SGQ3	Pseudomonas_phage	3.2e-116	39.9
WP_012621963.1\|862629_863520_-	hypothetical protein	J9SW46	Pseudomonas_phage	3.2e-24	28.5
WP_012621964.1\|863548_863851_-	IclR family transcriptional regulator	A0A0S4L7B4	Pseudomonas_phage	3.3e-13	41.8
WP_012621965.1\|863847_863991_-	hypothetical protein	NA	NA	NA	NA
WP_012621966.1\|864046_864295_+	hypothetical protein	NA	NA	NA	NA
WP_012621967.1\|864487_864721_-	DNA-binding protein	NA	NA	NA	NA
WP_012621968.1\|864784_865084_+	hypothetical protein	NA	NA	NA	NA
WP_041603138.1\|865279_865639_+	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_012621970.1\|865686_866658_+	nucleoid-associated protein	A0A291AUQ0	Sinorhizobium_phage	1.2e-48	35.7
WP_012621971.1\|866657_867836_+	hypothetical protein	NA	NA	NA	NA
WP_012621972.1\|867929_868451_+	glycoside hydrolase family 108 protein	A0A0M3LSH2	Mannheimia_phage	6.6e-70	76.4
WP_012621973.1\|868551_868785_+	DUF2644 domain-containing protein	F6MIK0	Haemophilus_phage	2.1e-23	74.7
WP_012621974.1\|868781_869135_+	DUF2681 domain-containing protein	F6MIK1	Haemophilus_phage	5.0e-29	64.1
WP_012621975.1\|869159_869489_+	DUF2730 domain-containing protein	M1Q558	Vibrio_phage	6.1e-05	28.0
WP_012621976.1\|869492_869783_+	hypothetical protein	A0A0C4UR00	Shigella_phage	8.8e-24	59.8
WP_012621977.1\|869816_870389_+	DUF3486 family protein	A0A2I7S9D1	Vibrio_phage	7.0e-33	43.0
WP_041603139.1\|870375_871686_+\|terminase	terminase	A0A2P9JZI8	Alteromonadaceae_phage	1.1e-158	66.0
WP_012621979.1\|871689_873108_+	DUF935 family protein	A4JWJ5	Burkholderia_virus	9.7e-124	49.3
WP_012621980.1\|873104_874373_+\|head	phage head morphogenesis protein	J9STS2	Pseudomonas_phage	9.7e-59	48.4
WP_012621981.1\|874499_874955_+	phage virion morphogenesis protein	J9SNH3	Pseudomonas_phage	7.3e-17	31.4
WP_012621982.1\|875175_876282_+	hypothetical protein	A4JWJ9	Burkholderia_virus	4.3e-71	41.9
WP_012621983.1\|876317_877259_+	hypothetical protein	A4JWK0	Burkholderia_virus	2.7e-53	38.4
WP_012621984.1\|877325_877769_+	hypothetical protein	NA	NA	NA	NA
877273:877291	attR	NA	NA	NA	NA
WP_012621985.1\|877771_878209_+	DUF1320 domain-containing protein	NA	NA	NA	NA
WP_012621986.1\|878208_878709_+	Gp37 family protein	NA	NA	NA	NA
WP_012621987.1\|878718_880113_+\|tail	phage tail sheath subtilisin-like domain-containing protein	A4JWK5	Burkholderia_virus	1.9e-111	47.8
WP_012621988.1\|880112_880631_+\|tail	phage major tail tube protein	A4JWK6	Burkholderia_virus	6.2e-36	43.7
WP_012621990.1\|881544_881805_+	hypothetical protein	NA	NA	NA	NA
WP_012621991.1\|881884_882172_+\|tail	phage tail assembly protein	NA	NA	NA	NA
WP_106380187.1\|882173_882302_+\|tail	GpE family phage tail protein	NA	NA	NA	NA
WP_012621993.1\|882286_882571_-	hypothetical protein	NA	NA	NA	NA
WP_012621994.1\|882614_885293_+\|tail	phage tail tape measure protein	A4JWL0	Burkholderia_virus	3.2e-27	22.7
WP_012621995.1\|885292_886234_+\|tail	phage tail protein	NA	NA	NA	NA
WP_012621996.1\|886226_886445_+\|tail	tail protein X	Q6QIA3	Burkholderia_phage	9.9e-12	46.3
WP_012621997.1\|886448_887501_+	hypothetical protein	Q6QIA2	Burkholderia_phage	1.8e-58	38.6
WP_012621998.1\|887515_888100_+\|plate	phage baseplate assembly protein V	NA	NA	NA	NA
WP_012621999.1\|888157_888526_+	GPW/gp25 family protein	NA	NA	NA	NA
WP_012622000.1\|888512_889628_+\|plate	baseplate J/gp47 family protein	Q6QI99	Burkholderia_phage	5.4e-53	35.1
WP_012622001.1\|889620_890187_+\|tail	phage tail protein	Q6QI98	Burkholderia_phage	1.0e-39	43.5
WP_012622003.1\|892136_892703_+	DUF4376 domain-containing protein	F6MIL9	Haemophilus_phage	9.9e-96	89.4
WP_012622004.1\|892695_893175_+	hypothetical protein	F6MIM0	Haemophilus_phage	1.9e-84	92.9
WP_049753190.1\|893386_896413_+	DUF1983 domain-containing protein	A0A0M3LQ61	Mannheimia_phage	3.0e-13	62.5
WP_012622006.1\|896441_897233_+	transferrin-binding protein-like solute binding protein	NA	NA	NA	NA
WP_005713881.1\|897572_898529_-	zinc ABC transporter substrate-binding protein ZnuA	NA	NA	NA	NA
WP_012622007.1\|898666_900034_-	CDP-diacylglycerol--serine O-phosphatidyltransferase	NA	NA	NA	NA
WP_012622009.1\|900539_903356_-\|tRNA	isoleucine--tRNA ligase	A0A2K9V7W4	Bandra_megavirus	7.2e-78	25.5
WP_012622010.1\|903415_904078_-	zeta toxin family protein	NA	NA	NA	NA
WP_010786335.1\|904081_904363_-	hypothetical protein	NA	NA	NA	NA
WP_041603250.1\|904364_905312_-	bifunctional riboflavin kinase/FAD synthetase	NA	NA	NA	NA
WP_012622012.1\|905500_906535_+	phosphoribosylformylglycinamidine cyclo-ligase	M4QRQ6	Synechococcus_phage	8.5e-69	42.2
WP_012622013.1\|906889_908578_-	hypothetical protein	NA	NA	NA	NA
WP_016527658.1\|908642_909017_-	hypothetical protein	NA	NA	NA	NA
WP_012622015.1\|908982_909573_-	hypothetical protein	NA	NA	NA	NA
WP_012621529.1\|909701_910673_+\|transposase	IS110 family transposase	A0A1S7J231	Thermus_phage	4.1e-09	28.8
WP_005712922.1\|910944_911724_-	outer membrane protein assembly factor BamD	NA	NA	NA	NA
WP_012622017.1\|911860_912838_+	23S rRNA pseudouridine(1911/1915/1917) synthase RluD	NA	NA	NA	NA
WP_012622018.1\|913157_913469_-	BolA/IbaG family iron-sulfur metabolism protein	NA	NA	NA	NA
WP_012622019.1\|913552_914140_+	hypothetical protein	NA	NA	NA	NA
WP_012622020.1\|914376_915111_+	16S rRNA (uracil(1498)-N(3))-methyltransferase	NA	NA	NA	NA
WP_012622021.1\|915111_915669_+	YqgE/AlgH family protein	NA	NA	NA	NA
WP_010786342.1\|915668_916085_+	Holliday junction resolvase RuvX	NA	NA	NA	NA
WP_012622022.1\|916103_917414_-	deoxyguanosinetriphosphate triphosphohydrolase family protein	NA	NA	NA	NA
WP_010786345.1\|919084_920680_+	ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_005712947.1\|920773_921778_+	ABC transporter permease subunit	NA	NA	NA	NA
WP_005712949.1\|921806_922700_+	ABC transporter permease subunit	NA	NA	NA	NA
WP_005712951.1\|922710_923694_+	dipeptide ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	1.4e-17	30.0
WP_010786347.1\|923708_924689_+	ABC transporter ATP-binding protein	G3M9Y6	Bacillus_virus	4.2e-17	27.3
WP_005712956.1\|924740_925319_-	crossover junction endodeoxyribonuclease RuvC	G3MA90	Bacillus_virus	3.2e-09	27.8
WP_010786349.1\|925392_925881_-	hypothetical protein	NA	NA	NA	NA
WP_010786350.1\|925998_926739_-	YebC/PmpR family DNA-binding transcriptional regulator	NA	NA	NA	NA
WP_010786351.1\|926877_927327_-	dihydroneopterin triphosphate diphosphatase	NA	NA	NA	NA
WP_010786352.1\|927690_928371_+	TolC family protein	NA	NA	NA	NA
WP_005712965.1\|928530_929376_+	dihydropteroate synthase	A0A0B5J4J5	Pandoravirus	9.5e-18	25.8
WP_010786353.1\|929390_929738_+	ArsC family reductase	NA	NA	NA	NA
WP_010786354.1\|929823_930444_+	dephospho-CoA kinase	NA	NA	NA	NA
WP_010786355.1\|930447_930642_+	DNA gyrase inhibitor YacG	NA	NA	NA	NA
WP_010786356.1\|930638_931661_-	DNA polymerase III subunit delta	NA	NA	NA	NA
WP_005712977.1\|931665_932160_-	hypothetical protein	NA	NA	NA	NA
WP_041603251.1\|932242_934828_-\|tRNA	leucine--tRNA ligase	A0A2H4PQS0	Staphylococcus_phage	3.0e-187	42.7

DBSCAN-SWA_5

1124039 : 1132504

Staphylococcus_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_005712132.1\|1124039_1125359_-	sodium:proton antiporter	A0A2H4J178	uncultured_Caudovirales_phage	1.5e-30	33.7
WP_015939636.1\|1125550_1127425_+	SurA N-terminal domain-containing protein	NA	NA	NA	NA
WP_010786214.1\|1127875_1128967_+	bifunctional diaminohydroxyphosphoribosylaminopyrimidine deaminase/5-amino-6-(5-phosphoribosylamino)uracil reductase RibD	A0A1V0SE20	Indivirus	7.1e-50	37.3
WP_010786213.1\|1128968_1129613_+	riboflavin synthase	A0A2H4PQS5	Staphylococcus_phage	2.1e-41	42.1
WP_015939637.1\|1129744_1130944_+	bifunctional 3,4-dihydroxy-2-butanone-4-phosphate synthase/GTP cyclohydrolase II	A0A2H4PQS2	Staphylococcus_phage	2.4e-99	49.2
WP_010786211.1\|1131139_1131601_+	6,7-dimethyl-8-ribityllumazine synthase	A0A2H4PQS3	Staphylococcus_phage	4.6e-43	58.8
WP_010786210.1\|1131712_1132504_-	ABC transporter ATP-binding protein	A0A285PWH2	Cedratvirus	3.1e-10	28.0

DBSCAN-SWA_6

1142835 : 1146500

Mannheimia_phage(66.67%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_015939643.1\|1142835_1143375_-	hypothetical protein	A0A0M3LPL3	Mannheimia_phage	2.9e-44	69.6
WP_010786201.1\|1143718_1143907_+	hypothetical protein	Q19US2	Mannheimia_phage	7.4e-08	50.0
WP_010786200.1\|1143948_1144563_-	YqaJ viral recombinase family protein	A0A0M3LPU0	Mannheimia_phage	7.4e-89	78.2
WP_015939644.1\|1144559_1145426_-	phage recombination protein Bet	A0A2H4JAQ4	uncultured_Caudovirales_phage	1.8e-56	54.4
WP_015939645.1\|1145435_1145894_-	hypothetical protein	A0A0M3LR66	Mannheimia_phage	4.0e-23	44.3
WP_015939646.1\|1145902_1146061_-	hypothetical protein	NA	NA	NA	NA
WP_016528517.1\|1146317_1146500_-	hypothetical protein	F6MIM4	Haemophilus_phage	1.3e-25	96.7

DBSCAN-SWA_7

1623951 : 1661810

Shigella_phage(15.38%)

transposase,tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_020997266.1\|1623951_1624134_+\|transposase	transposase	F6MIM4	Haemophilus_phage	1.7e-25	96.7
WP_015939868.1\|1624600_1626373_-\|tRNA	aspartate--tRNA ligase	A0A2K9L3L6	Tupanvirus	3.0e-13	30.7
WP_005712850.1\|1626552_1627152_+	nucleotide exchange factor GrpE	NA	NA	NA	NA
WP_015939869.1\|1627248_1627551_+	hypothetical protein	NA	NA	NA	NA
WP_015939870.1\|1627614_1628067_+	DUF441 domain-containing protein	NA	NA	NA	NA
WP_015939871.1\|1628081_1632020_+	ATP-dependent RNA helicase HrpA	A0A1V0SBU4	Catovirus	5.0e-45	25.6
WP_015939872.1\|1632227_1633418_+\|tRNA	tyrosine--tRNA ligase	NA	NA	NA	NA
WP_015939873.1\|1633507_1634644_-	alanine racemase	NA	NA	NA	NA
WP_005712838.1\|1634767_1635682_+	SPFH/Band 7/PHB domain protein	NA	NA	NA	NA
WP_015939874.1\|1635691_1636132_+	NfeD family protein	NA	NA	NA	NA
WP_015939875.1\|1636206_1637433_-	uracil-xanthine permease	Q9KX94	Enterobacteria_phage	2.3e-57	36.5
WP_005712834.1\|1637627_1638923_-	NCS2 family permease	A0A0R6PHV4	Moraxella_phage	4.0e-68	37.0
WP_080513251.1\|1639108_1639249_-	glutathionylspermidine synthase family protein	I3WVW4	Acinetobacter_phage	2.9e-09	61.0
WP_010786500.1\|1639661_1640411_-	SDR family oxidoreductase	NA	NA	NA	NA
WP_005712827.1\|1640466_1641129_-	carbonate dehydratase	NA	NA	NA	NA
WP_012621529.1\|1641486_1642458_+\|transposase	IS110 family transposase	A0A1S7J231	Thermus_phage	4.1e-09	28.8
WP_005712825.1\|1642647_1643334_+	lipoprotein-releasing ABC transporter ATP-binding protein LolD	G9BWD6	Planktothrix_phage	2.8e-36	39.0
WP_010786501.1\|1643333_1644584_+	lipoprotein-releasing ABC transporter permease subunit LolE	NA	NA	NA	NA
WP_010786502.1\|1644617_1645604_-	amidohydrolase family protein	A0A076FFX9	Aureococcus_anophage	3.5e-32	29.4
WP_010786503.1\|1645845_1646619_-\|tRNA	tRNA cyclic N6-threonylcarbamoyladenosine(37) synthase TcdA	S4VW33	Pandoravirus	5.3e-15	28.0
WP_010786504.1\|1646664_1647948_-	NAD(P)/FAD-dependent oxidoreductase	NA	NA	NA	NA
WP_010786505.1\|1648286_1649036_-	class I SAM-dependent methyltransferase	NA	NA	NA	NA
WP_010786506.1\|1649056_1650007_-	lauroyl-Kdo(2)-lipid IV(A) myristoyltransferase	NA	NA	NA	NA
WP_015939877.1\|1650016_1650706_-	electron transport complex subunit E	NA	NA	NA	NA
WP_015939878.1\|1650895_1651438_-\|transposase	transposase	NA	NA	NA	NA
WP_015939879.1\|1651471_1652110_-	electron transport complex subunit RsxG	NA	NA	NA	NA
WP_010786510.1\|1652106_1653174_-	electron transport complex subunit RsxD	NA	NA	NA	NA
WP_005712807.1\|1653204_1653837_-	trimeric intracellular cation channel family protein	NA	NA	NA	NA
WP_010786511.1\|1653915_1655916_-	electron transport complex subunit RsxC	NA	NA	NA	NA
WP_010786512.1\|1655905_1656514_-	electron transport complex subunit RsxB	NA	NA	NA	NA
WP_010786513.1\|1656513_1657095_-	electron transport complex subunit RsxA	NA	NA	NA	NA
WP_015939880.1\|1657130_1657283_+	hypothetical protein	NA	NA	NA	NA
WP_005714908.1\|1659413_1660400_-\|transposase	IS110 family transposase	Q75QL1	Wolbachia_phage	9.7e-22	32.7
WP_015939882.1\|1660662_1660986_+\|transposase	IS3 family transposase	Q716C1	Shigella_phage	2.4e-14	43.4
WP_041603172.1\|1661588_1661810_+\|transposase	transposase	Q716C2	Shigella_phage	1.0e-16	58.0

DBSCAN-SWA_8

2051955 : 2123371

Wolbachia_phage(11.76%)

protease,transposase,integrase,tRNA

attL 2051930:2051989|attR 2066481:2067695

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
2051930:2051989	attL	NA	NA	NA	NA
WP_005714908.1\|2051955_2052942_-\|transposase	IS110 family transposase	Q75QL1	Wolbachia_phage	9.7e-22	32.7
WP_041603294.1\|2053414_2054509_-\|integrase	integrase arm-type DNA-binding domain-containing protein	A0A1B5FPC6	Escherichia_phage	6.2e-70	41.3
WP_010787229.1\|2055361_2056144_+	amino acid ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_010787230.1\|2056133_2056850_+	amino acid ABC transporter permease	NA	NA	NA	NA
WP_010787231.1\|2056852_2057602_+	amino acid ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	3.7e-34	40.1
WP_010787233.1\|2058100_2060143_+	DUF262 domain-containing protein	NA	NA	NA	NA
WP_010787234.1\|2060270_2061698_-	FAD-dependent oxidoreductase	NA	NA	NA	NA
WP_005714908.1\|2066506_2067493_-\|transposase	IS110 family transposase	Q75QL1	Wolbachia_phage	9.7e-22	32.7
WP_010786076.1\|2074075_2074387_-	RidA family protein	NA	NA	NA	NA
2066481:2067695	attR	NA	NA	NA	NA
WP_005710363.1\|2074455_2075475_-	branched-chain amino acid aminotransferase	NA	NA	NA	NA
WP_015940068.1\|2075913_2076810_+	transcriptional regulator GcvA	Q6JIH3	Burkholderia_virus	9.4e-24	30.2
WP_010786074.1\|2076831_2077506_+	pyrimidine 5'-nucleotidase	NA	NA	NA	NA
WP_010786073.1\|2077523_2078507_+	HTH-type transcriptional regulator CysB	NA	NA	NA	NA
WP_005710367.1\|2079351_2080179_+	3',5'-cyclic-AMP phosphodiesterase	NA	NA	NA	NA
WP_010786071.1\|2080273_2081263_-	2-hydroxyacid dehydrogenase	M1I4S0	Paramecium_bursaria_Chlorella_virus	7.1e-65	40.1
WP_005710371.1\|2081272_2082340_-	hypothetical protein	NA	NA	NA	NA
WP_005710372.1\|2082336_2083299_-	DNA cytosine methyltransferase	A7XXH6	Thermus_virus	1.1e-75	45.0
WP_005710374.1\|2083306_2084416_-	flavodoxin-dependent (E)-4-hydroxy-3-methylbut-2-enyl-diphosphate synthase	NA	NA	NA	NA
WP_015940071.1\|2084417_2085500_-	DUF4115 domain-containing protein	NA	NA	NA	NA
WP_015940072.1\|2085635_2087501_-	signal peptide peptidase SppA	A0A2H4UUF9	Bodo_saltans_virus	7.7e-12	23.1
WP_015940073.1\|2087719_2089501_+	lipid A ABC transporter ATP-binding protein/permease MsbA	W8CYL7	Bacillus_phage	1.0e-66	32.4
WP_005710383.1\|2089640_2090324_+	nicotinamide riboside transporter PnuC	U5J9C5	Bacillus_phage	1.0e-38	37.8
WP_005710385.1\|2090416_2091127_+	DnaA regulatory inactivator Hda	NA	NA	NA	NA
WP_015940075.1\|2091127_2091754_+	cytochrome c biogenesis heme-transporting ATPase CcmA	NA	NA	NA	NA
WP_005710389.1\|2091763_2092426_+	heme exporter protein CcmB	NA	NA	NA	NA
WP_010786066.1\|2092472_2093213_+	heme ABC transporter permease	NA	NA	NA	NA
WP_005710392.1\|2093221_2093416_+	heme exporter protein CcmD	NA	NA	NA	NA
WP_015940076.1\|2093580_2094969_+	DASS family sodium-coupled anion symporter	NA	NA	NA	NA
WP_041603198.1\|2095207_2096383_+	phosphoglycerate kinase	NA	NA	NA	NA
WP_015940078.1\|2096527_2097607_+	class II fructose-bisphosphate aldolase	NA	NA	NA	NA
WP_015940080.1\|2097779_2098580_+	ABC transporter ATP-binding protein	A0A2H4PQG7	Staphylococcus_phage	3.9e-13	29.9
WP_015940081.1\|2098592_2099231_+	nitroreductase family protein	NA	NA	NA	NA
WP_026916780.1\|2099337_2099853_+	TIGR00645 family protein	K4K6D8	Caulobacter_phage	5.6e-21	32.3
WP_015940083.1\|2099937_2101236_-	FAD-binding oxidoreductase	NA	NA	NA	NA
WP_010786058.1\|2101769_2102249_-	transcription elongation factor GreB	NA	NA	NA	NA
WP_015940084.1\|2102248_2103184_-	KpsF/GutQ family sugar-phosphate isomerase	A0A2P0VNK5	Tetraselmis_virus	8.0e-42	37.4
WP_010786056.1\|2103245_2103827_-	type IV pilus biogenesis/stability protein PilW	NA	NA	NA	NA
WP_012621529.1\|2103874_2104846_-\|transposase	IS110 family transposase	A0A1S7J231	Thermus_phage	4.1e-09	28.8
WP_015940085.1\|2105088_2106249_-\|tRNA	bifunctional tRNA (adenosine(37)-C2)-methyltransferase TrmG/ribosomal RNA large subunit methyltransferase RlmN	NA	NA	NA	NA
WP_005710405.1\|2106449_2106758_-	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_015940087.1\|2107933_2109373_+\|tRNA	glutamate--tRNA ligase	NA	NA	NA	NA
WP_010786049.1\|2112006_2112381_-	Soluble cytochrome b562	NA	NA	NA	NA
WP_015940089.1\|2112440_2113676_-	beta-ketoacyl-ACP synthase I	NA	NA	NA	NA
WP_015940090.1\|2113833_2116980_-	DEAD/DEAH box helicase family protein	A0A2K5B256	Erysipelothrix_phage	6.4e-128	32.0
WP_041603297.1\|2116992_2118882_-	site-specific DNA-methyltransferase	A0A2K5B2C1	Erysipelothrix_phage	2.7e-121	41.3
WP_010786047.1\|2118936_2119242_-	DUF4391 domain-containing protein	NA	NA	NA	NA
WP_015940092.1\|2119685_2120984_-	adenylosuccinate synthase	A0A285PX35	Cedratvirus	1.9e-73	36.6
WP_010786045.1\|2121266_2122154_-\|protease	protease modulator HflC	NA	NA	NA	NA
WP_015940093.1\|2122156_2123371_-\|protease	FtsH protease activity modulator HflK	NA	NA	NA	NA

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. NC_011852

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CRISPR-Cas detection and classification

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Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection