CRISPRimmunity

Please click to download your results

Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NC_011992	Acidovorax ebreus TPSY, complete sequence	3 crisprs	DEDDh,cas2,cas1,cas9,WYL,csa3,DinG,Cas9_archaeal,PD-DExK	0	11	4	0

Results visualization

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Crispr_ID: NC_011992_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_011992_1

61495-62454

TypeII

Consensus_repeat	Method
GTTGTAGCTCCCTCTCTCACCCCGGATAGCTACACT	CRISPRCasFinder
GTTGTAGCTCCCTCTCTCACCCCGGATAGCTACACT	CRT
GTTGTAGCTCCCTCTCTCACCCCGGATAGCTACACT	PILER-CR

14 spacers

cas2,cas1,cas9

The CRISPR arrays of NC_011992_1

>merge|NC_011992|1|61495-62454|CRISPRCasFinder,CRT,PILER-CR
GTCATAGCTCCCTCTCTCACCCCGGATAGCTACACTACGCCCATATCGGCCCACTGAGCGATATTCGTTGTAGCTCCCTCTCTCACCCCGGATAGCTACACTCGGCAGGGTTTGGGGGAGGCGATTAAATTTGTTGTAGCTCCCTCTCTCACCCCGGATAGCTACACTCAGCTATGCAGCGCAGGGCATATGCTGCATGTTGTAGCTCCCTCTCTCACCCCGGATAGCTACACTGAAAGCAGGTCCGGCAAGCTACGCGCGACAGTTGTAGCTCCCTCTCTCACCCCGGATAGCTACACTGAAAGCAGGTCCGGCAAGCTACGCGCGACAGTTGTAGCTCCCTCTCTCACCCCGGATAGCTACACTATCAGCCTGAGCCTTTGCAGAGGCTTCCTCGTTGTAGCTCCCTCTCTCACCCCGGATAGCTACACTCATTCCCCCCGTGGCTCGTAATTTCGCATTGTTGTAGCTCCCTCTCTCACCCCGGATAGCTACACTTCGATGTAAGTCACCCCTGCCTTTTCTAGCGTTGTAGCTCCCTCTCTCACCCCGGATAGCTACACTTGAGCAGTTCGTCTACTGCGCGGAAGCCAGGTTGTAGCTCCCTCTCTCACCCCGGATAGCTACACTATAACCACTTGGATGGCCTGCGACGGCGGCGTTGTAGCTCCCTCTCTCACCCCGGATAGCTACACTGGATCGCCGTGGGTAATGCGAACGACGTTAGTTGTAGCTCCCTCTCTCACCCCGGATAGCTACACTAACACGTTCCCAGCGGCCTTTTGGGCGTCCGTTGTAGCTCCCTCTCTCACCCCGGATAGCTACACTGGCTACGCCCGGCGCGAAGAGGCCATCGCTGTTGTAGCTCCCTCTCTCACCCCGGATAGCTACACTCTGGACGGAGGGACAACAGCATGAGCGAGAGTTGTAGCTCCCTCTCTCACCCCGGATAGCTACACT

>NC_011992|1|1|61495-62454|CRISPRCasFinder
GTCATAGCTCCCTCTCTCACCCCGGATAGCTACACT	ACGCCCATATCGGCCCACTGAGCGATATTC
GTTGTAGCTCCCTCTCTCACCCCGGATAGCTACACT	CGGCAGGGTTTGGGGGAGGCGATTAAATTT
GTTGTAGCTCCCTCTCTCACCCCGGATAGCTACACT	CAGCTATGCAGCGCAGGGCATATGCTGCAT
GTTGTAGCTCCCTCTCTCACCCCGGATAGCTACACT	GAAAGCAGGTCCGGCAAGCTACGCGCGACA
GTTGTAGCTCCCTCTCTCACCCCGGATAGCTACACT	GAAAGCAGGTCCGGCAAGCTACGCGCGACA
GTTGTAGCTCCCTCTCTCACCCCGGATAGCTACACT	ATCAGCCTGAGCCTTTGCAGAGGCTTCCTC
GTTGTAGCTCCCTCTCTCACCCCGGATAGCTACACT	CATTCCCCCCGTGGCTCGTAATTTCGCATT
GTTGTAGCTCCCTCTCTCACCCCGGATAGCTACACT	TCGATGTAAGTCACCCCTGCCTTTTCTAGC
GTTGTAGCTCCCTCTCTCACCCCGGATAGCTACACT	TGAGCAGTTCGTCTACTGCGCGGAAGCCAG
GTTGTAGCTCCCTCTCTCACCCCGGATAGCTACACT	ATAACCACTTGGATGGCCTGCGACGGCGGC
GTTGTAGCTCCCTCTCTCACCCCGGATAGCTACACT	GGATCGCCGTGGGTAATGCGAACGACGTTA
GTTGTAGCTCCCTCTCTCACCCCGGATAGCTACACT	AACACGTTCCCAGCGGCCTTTTGGGCGTCC
GTTGTAGCTCCCTCTCTCACCCCGGATAGCTACACT	GGCTACGCCCGGCGCGAAGAGGCCATCGCT
GTTGTAGCTCCCTCTCTCACCCCGGATAGCTACACT	CTGGACGGAGGGACAACAGCATGAGCGAGA
GTTGTAGCTCCCTCTCTCACCCCGGATAGCTACACT

>NC_011992|1|1|61495-62454|CRT
GTCATAGCTCCCTCTCTCACCCCGGATAGCTACACT	ACGCCCATATCGGCCCACTGAGCGATATTC
GTTGTAGCTCCCTCTCTCACCCCGGATAGCTACACT	CGGCAGGGTTTGGGGGAGGCGATTAAATTT
GTTGTAGCTCCCTCTCTCACCCCGGATAGCTACACT	CAGCTATGCAGCGCAGGGCATATGCTGCAT
GTTGTAGCTCCCTCTCTCACCCCGGATAGCTACACT	GAAAGCAGGTCCGGCAAGCTACGCGCGACA
GTTGTAGCTCCCTCTCTCACCCCGGATAGCTACACT	GAAAGCAGGTCCGGCAAGCTACGCGCGACA
GTTGTAGCTCCCTCTCTCACCCCGGATAGCTACACT	ATCAGCCTGAGCCTTTGCAGAGGCTTCCTC
GTTGTAGCTCCCTCTCTCACCCCGGATAGCTACACT	CATTCCCCCCGTGGCTCGTAATTTCGCATT
GTTGTAGCTCCCTCTCTCACCCCGGATAGCTACACT	TCGATGTAAGTCACCCCTGCCTTTTCTAGC
GTTGTAGCTCCCTCTCTCACCCCGGATAGCTACACT	TGAGCAGTTCGTCTACTGCGCGGAAGCCAG
GTTGTAGCTCCCTCTCTCACCCCGGATAGCTACACT	ATAACCACTTGGATGGCCTGCGACGGCGGC
GTTGTAGCTCCCTCTCTCACCCCGGATAGCTACACT	GGATCGCCGTGGGTAATGCGAACGACGTTA
GTTGTAGCTCCCTCTCTCACCCCGGATAGCTACACT	AACACGTTCCCAGCGGCCTTTTGGGCGTCC
GTTGTAGCTCCCTCTCTCACCCCGGATAGCTACACT	GGCTACGCCCGGCGCGAAGAGGCCATCGCT
GTTGTAGCTCCCTCTCTCACCCCGGATAGCTACACT	CTGGACGGAGGGACAACAGCATGAGCGAGA
GTTGTAGCTCCCTCTCTCACCCCGGATAGCTACACT

>NC_011992|1|1|61561-62454|PILER-CR
GTTGTAGCTCCCTCTCTCACCCCGGATAGCTACACT	CGGCAGGGTTTGGGGGAGGCGATTAAATTT
GTTGTAGCTCCCTCTCTCACCCCGGATAGCTACACT	CAGCTATGCAGCGCAGGGCATATGCTGCAT
GTTGTAGCTCCCTCTCTCACCCCGGATAGCTACACT	GAAAGCAGGTCCGGCAAGCTACGCGCGACA
GTTGTAGCTCCCTCTCTCACCCCGGATAGCTACACT	GAAAGCAGGTCCGGCAAGCTACGCGCGACA
GTTGTAGCTCCCTCTCTCACCCCGGATAGCTACACT	ATCAGCCTGAGCCTTTGCAGAGGCTTCCTC
GTTGTAGCTCCCTCTCTCACCCCGGATAGCTACACT	CATTCCCCCCGTGGCTCGTAATTTCGCATT
GTTGTAGCTCCCTCTCTCACCCCGGATAGCTACACT	TCGATGTAAGTCACCCCTGCCTTTTCTAGC
GTTGTAGCTCCCTCTCTCACCCCGGATAGCTACACT	TGAGCAGTTCGTCTACTGCGCGGAAGCCAG
GTTGTAGCTCCCTCTCTCACCCCGGATAGCTACACT	ATAACCACTTGGATGGCCTGCGACGGCGGC
GTTGTAGCTCCCTCTCTCACCCCGGATAGCTACACT	GGATCGCCGTGGGTAATGCGAACGACGTTA
GTTGTAGCTCCCTCTCTCACCCCGGATAGCTACACT	AACACGTTCCCAGCGGCCTTTTGGGCGTCC
GTTGTAGCTCCCTCTCTCACCCCGGATAGCTACACT	GGCTACGCCCGGCGCGAAGAGGCCATCGCT
GTTGTAGCTCCCTCTCTCACCCCGGATAGCTACACT	CTGGACGGAGGGACAACAGCATGAGCGAGA
GTTGTAGCTCCCTCTCTCACCCCGGATAGCTACACT

Protein	Signature genes	Signature genes Name	Protein_function
NC_011992.1\|WP_148215398.1\|57197_58028_-\|helix-turn-helix-domain-containing-protein	unknown	unknown	gnl\|CDD\|380379
NC_011992.1\|WP_041838918.1\|56556_57132_+\|hypothetical-protein	unknown	unknown	unknown
NC_011992.1\|WP_012655174.1\|62518_62827_-\|CRISPR-associated-endonuclease-Cas2	cas2	COG3512_cas2_CAS-II-A:CAS-II-B:CAS-II-C	gnl\|CDD\|226043
NC_011992.1\|WP_012655176.1\|63758_67154_-\|type-II-CRISPR-RNA-guided-endonuclease-Cas9	cas9	COG3513_cas9_CAS-II-A:CAS-II-B:CAS-II-C	gnl\|CDD\|226044
NC_011992.1\|WP_012655177.1\|67349_68774_-\|FAD-binding-protein	unknown	unknown	gnl\|CDD\|178402
NC_011992.1\|WP_012655180.1\|70492_70915_-\|hotdog-fold-thioesterase	unknown	unknown	gnl\|CDD\|161843
NC_011992.1\|WP_012655171.1\|58177_59425_+\|MFS-transporter	unknown	unknown	gnl\|CDD\|340883
NC_011992.1\|WP_012655166.1\|53146_54142_+\|ParB/RepB/Spo0J-family-partition-protein	unknown	unknown	gnl\|CDD\|275105
NC_011992.1\|WP_012655179.1\|69561_70134_+\|cob(I)yrinic-acid-a,c-diamide-adenosyltransferase	unknown	unknown	gnl\|CDD\|376665
NC_011992.1\|WP_041838768.1\|72542_74009_-\|acetyl-CoA-hydrolase/transferase-family-protein	unknown	unknown	gnl\|CDD\|274588
NC_011992.1\|WP_012655164.1\|51740_52511_+\|ParA-family-protein	unknown	unknown	gnl\|CDD\|379293
NC_011992.1\|WP_012655165.1\|52597_53140_+\|serine-hydrolase-family-protein	unknown	unknown	gnl\|CDD\|226075
NC_011992.1\|WP_012655183.1\|74262_74994_+\|zf-TFIIB-domain-containing-protein	unknown	unknown	gnl\|CDD\|379195
NC_011992.1\|WP_012655173.1\|60622_61225_+\|NAD(P)H:quinone-oxidoreductase	unknown	unknown	gnl\|CDD\|179647
NC_011992.1\|WP_012655167.1\|54167_54965_+\|type-12-methyltransferase	unknown	unknown	gnl\|CDD\|369778
NC_011992.1\|WP_012655181.1\|71138_72296_+\|ABC-transporter-substrate-binding-protein	unknown	unknown	gnl\|CDD\|380549
NC_011992.1\|WP_012655178.1\|69025_69406_-\|calcium-binding-protein	unknown	unknown	gnl\|CDD\|320029
NC_011992.1\|WP_012655172.1\|59740_60484_+\|gamma-glutamylcyclotransferase	unknown	unknown	gnl\|CDD\|226226
NC_011992.1\|WP_148215399.1\|62863_63757_-\|type-II-CRISPR-associated-endonuclease-Cas1	cas1	cd09720_cas1_CAS-II-A:CAS-II-B:CAS-II-C	gnl\|CDD\|274694
NC_011992.1\|WP_012655168.1\|55130_56171_+\|peptidoglycan-binding-protein	unknown	unknown	gnl\|CDD\|366659

Protein	Function_ID	Function_description	E-value
NC_011992.1\|WP_012655168.1\|55130_56171_+\|peptidoglycan-binding-protein	gnl\|CDD\|366659	pfam01471, PG_binding_1, Putative peptidoglycan binding domain. This domain is composed of three alpha helices. This domain is found at the N or C-terminus of a variety of enzymes involved in bacterial cell wall degradation. This domain may have a general peptidoglycan binding function. This family is found N-terminal to the catalytic domain of matrixins. The domain is found to bind peptidoglycan experimentally.	7.74454e-17
NC_011992.1\|WP_148215398.1\|57197_58028_-\|helix-turn-helix-domain-containing-protein	gnl\|CDD\|380379	cd06124, cupin_NimR-like_N, AraC/XylS family transcriptional regulators similar to NimR, N-terminal cupin domain. This family contains mostly bacterial proteins containing an AraC/XylS family helix-turn-helix (HTH) DNA-binding domain C-terminal to a cupin domain, and may be possible transcriptional regulators. Included in this family is Escherichia coli HTH-type transcriptional regulator NimR (also called YeaM) that negatively regulates expression of the nimT operon and its own expression. Proteins in this family belong to the cupin superfamily with a conserved "jelly roll-like" beta-barrel fold capable of homodimerization.	1.37762e-26
NC_011992.1\|WP_012655179.1\|69561_70134_+\|cob(I)yrinic-acid-a,c-diamide-adenosyltransferase	gnl\|CDD\|376665	pfam01923, Cob_adeno_trans, Cobalamin adenosyltransferase. Cobalamin adenosyltransferase This family contains the gene products of PduO and EutT which are both cobalamin adenosyltransferases. PduO is a protein with ATP:cob(I)alamin adenosyltransferase activity. The main role of this protein is the conversion of inactive cobalamins to AdoCbl for 1,2-propanediol degradation.The EutT enzyme appears to be an adenosyl transferase, converting CNB12 to AdoB12.	7.00223e-70
NC_011992.1\|WP_012655174.1\|62518_62827_-\|CRISPR-associated-endonuclease-Cas2	gnl\|CDD\|226043	COG3512, COG3512, CRISPR-associated protein, Cas2 homolog [Defense mechanisms].	9.21282e-42
NC_011992.1\|WP_012655176.1\|63758_67154_-\|type-II-CRISPR-RNA-guided-endonuclease-Cas9	gnl\|CDD\|226044	COG3513, COG3513, Predicted CRISPR-associated nuclease, contains McrA/HNH-nuclease and RuvC-like nuclease domain [Defense mechanisms].	0
NC_011992.1\|WP_012655177.1\|67349_68774_-\|FAD-binding-protein	gnl\|CDD\|178402	PLN02805, PLN02805, D-lactate dehydrogenase [cytochrome].	5.90633e-147
NC_011992.1\|WP_012655180.1\|70492_70915_-\|hotdog-fold-thioesterase	gnl\|CDD\|161843	TIGR00369, Putative_esterase, uncharacterized domain 1. Most proteins containing this domain consist almost entirely of a single copy of this domain. A protein from C. elegans consists of two tandem copies of the domain. The domain is also found as the N-terminal region of an apparent initiation factor eIF-2B alpha subunit of Aquifex aeolicus. The function of the domain is unknown.	7.08883e-44
NC_011992.1\|WP_148215399.1\|62863_63757_-\|type-II-CRISPR-associated-endonuclease-Cas1	gnl\|CDD\|274694	TIGR03639, cas1_NMENI, CRISPR-associated endonuclease Cas1, subtype II/NMENI. The CRISPR-associated protein Cas1 is virtually universal to CRISPR systems. CRISPR, an acronym for Clustered Regularly Interspaced Short Palindromic Repeats, is a prokaryotic immunity system for foreign DNA, mostly from phage. CRISPR systems belong to different subtypes, distinguished by both nature of the repeats, the makeup of the cohort of associated Cas proteins, and by molecular phylogeny within the more universal Cas proteins such as this one. This model is of type EXCEPTION and provides more specific information than the EQUIVALOG model TIGR00287. It describes the Cas1 variant of the NMENI subtype of CRISPR/Cas system.	1.48305e-95
NC_011992.1\|WP_012655166.1\|53146_54142_+\|ParB/RepB/Spo0J-family-partition-protein	gnl\|CDD\|275105	TIGR04285, parB-like_partition_protein, nucleoid occlusion protein. This model describes nucleoid occlusion protein, a close homolog to ParB chromosome partitioning proteins including Spo0J in Bacillus subtilis. Its gene often is located near the gene for the Spo0J ortholog. This protein bind a specific DNA sequence and blocks cytokinesis from happening until chromosome segregation is complete.	6.27881e-72
NC_011992.1\|WP_041838768.1\|72542_74009_-\|acetyl-CoA-hydrolase/transferase-family-protein	gnl\|CDD\|274588	TIGR03458, Propionyl-CoA:succinate_CoA_transferase, succinate CoA transferase. This family of CoA transferases includes enzymes catalyzing at least two related but distinct activities. The E. coli YgfH protein has been characterized as a propionyl-CoA:succinate CoA transferase where it appears to be involved in a pathway for the decarboxylation of succinate to propionate. The Clostridium kluyveri CAT1 protein has been characterized as a acetyl-CoA:succinate CoA transferase and is believed to be involved in anaerobic succinate degradation. The propionate:succinate transferase activity has been reported in the propionic acid fermentation of propionibacterium species, where it is distinct from the coupled activities of distinct nucleotide-triphosphate dependent succinate and propionate/acetate CoA transferases (as inferred from activity in the absence of NTPs). The family represented by this model includes a member from Propionibacterium acnes KPA171202 which is likely to be responsible for this activity. A closely related clade not included in this family are the Ach1p proteins of fungi which are acetyl-CoA hydrolases. This name has been applied to many of the proteins represented by this model, possibly erroneously.	0
NC_011992.1\|WP_012655171.1\|58177_59425_+\|MFS-transporter	gnl\|CDD\|340883	cd17325, MFS_MdtG_SLC18_like, bacterial MdtG-like and eukaryotic solute carrier 18 (SLC18) family of the Major Facilitator Superfamily of transporters. This family is composed of eukaryotic solute carrier 18 (SLC18) family transporters and related bacterial multidrug resistance (MDR) transporters including several proteins from Escherichia coli such as multidrug resistance protein MdtG, from Bacillus subtilis such as multidrug resistance proteins 1 (Bmr1) and 2 (Bmr2), and from Staphylococcus aureus such as quinolone resistance protein NorA. The family also includes Escherichia coli arabinose efflux transporters YfcJ and YhhS. MDR transporters are drug/H+ antiporters (DHA) that mediate the efflux of a variety of drugs and toxic compounds, and confer resistance to these compounds. The SLC18 transporter family includes vesicular monoamine transporters (VAT1 and VAT2), vesicular acetylcholine transporter (VAChT), and SLC18B1, which is proposed to be a vesicular polyamine transporter (VPAT). The MdtG/SLC18 family belongs to the Major Facilitator Superfamily (MFS) of membrane transport proteins, which are thought to function through a single substrate binding site, alternating-access mechanism involving a rocker-switch type of movement.	3.00375e-28
NC_011992.1\|WP_012655165.1\|52597_53140_+\|serine-hydrolase-family-protein	gnl\|CDD\|226075	COG3545, COG3545, Predicted esterase of the alpha/beta hydrolase fold [General function prediction only].	1.73851e-63
NC_011992.1\|WP_012655183.1\|74262_74994_+\|zf-TFIIB-domain-containing-protein	gnl\|CDD\|379195	pfam13453, zf-TFIIB, Transcription factor zinc-finger.	0.000149185
NC_011992.1\|WP_012655172.1\|59740_60484_+\|gamma-glutamylcyclotransferase	gnl\|CDD\|226226	COG3703, ChaC, Uncharacterized protein involved in cation transport [Inorganic ion transport and metabolism].	2.18258e-48
NC_011992.1\|WP_012655167.1\|54167_54965_+\|type-12-methyltransferase	gnl\|CDD\|369778	pfam08242, Methyltransf_12, Methyltransferase domain. Members of this family are SAM dependent methyltransferases.	0.000287854
NC_011992.1\|WP_012655181.1\|71138_72296_+\|ABC-transporter-substrate-binding-protein	gnl\|CDD\|380549	cd06326, PBP1_ABC_ligand_binding-like, periplasmic ligand-binding domain of uncharacterized ABC-type transport systems predicted to be involved in uptake of amino acids, peptides, or inorganic ions. This group includes the type 1 periplasmic ligand-binding domain of uncharacterized ABC (ATPase Binding Cassette)-type transport systems that are predicted to be involved in the uptake of amino acids, peptides, or inorganic ions. This subgroup has high sequence similarity to members of the family of hydrophobic amino acid transporters (HAAT), such as leucine-isoleucine-valine binding protein (LIVBP); its ligand specificity has not been determined experimentally, however.	3.92615e-122
NC_011992.1\|WP_012655178.1\|69025_69406_-\|calcium-binding-protein	gnl\|CDD\|320029	cd15898, EFh_PI-PLC, EF-hand motif found in eukaryotic phosphoinositide-specific phospholipase C (PI-PLC, EC 3.1.4.11) isozymes. PI-PLC isozymes are signaling enzymes that hydrolyze the membrane phospholipids phosphatidylinositol-4,5-bisphosphate (PIP2) to generate two important second messengers in eukaryotic signal transduction cascades, Inositol 1,4,5-trisphosphate (InsP3) and diacylglycerol (DAG). InsP3 triggers inflow of calcium from intracellular stores, while DAG, together with calcium, activates protein kinase C, which goes on to phosphorylate other molecules, leading to altered cellular activity. Calcium is required for the catalysis. This family corresponds to the four EF-hand motifs containing PI-PLC isozymes, including PI-PLC-beta (1-4), -gamma (1-2), -delta (1,3,4), -epsilon (1), -zeta (1), eta (1-2). Lower eukaryotes such as yeast and slime molds contain only delta-type isozymes. In contrast, other types of isoforms present in higher eukaryotes. This family also includes 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase 1 (PLC1) from fungi. Some homologs from plants contain only two atypical EF-hand motifs and they are not included. All PI-PLC isozymes except sperm-specific PI-PLC-zeta share a core set of domains, including an N-terminal pleckstrin homology (PH) domain, four atypical EF-hand motifs, a PLC catalytic core, and a single C2 domain. PI-PLC-zeta lacks the PH domain. The PLC catalytic core domain is a TIM barrel with two highly conserved regions (X and Y) split by a highly degenerate linker sequence. Most of EF-hand motifs found in PI-PLCs consist of a helix-loop-helix structure, but lack residues critical to metal binding. Moreover, the EF-hand region of most of PI-PLCs may have an important regulatory function, but it has yet to be identified. However, PI-PLC-zeta is a key exception. It is responsible for Ca2+ oscillations in fertilized oocytes and exhibits a high sensitivity to Ca2+ mediated through its EF-hand domain. In addition, PI-PLC-eta2 shows a canonical EF-loop directing Ca2+-sensitivity and thus can amplify transient Ca2+ signals. Also it appears that PI-PLC-delta1 can regulate the binding of PH domain to PIP2 in a Ca2+-dependent manner through its functionally important EF-hand domains. PI-PLCs can be activated by a variety of extracellular ligands, such as growth factors, hormones, cytokines and lipids. Their activation has been implicated in tumorigenesis and/or metastasis linked to migration, proliferation, growth, inflammation, angiogenesis and actin cytoskeleton reorganization. PI-PLC-beta isozymes are activated by G-protein coupled receptor (GPCR) through different mechanisms. However, PI-PLC-gamma isozymes are activated by receptor tyrosine kinase (RTK), such as Rho and Ras GTPases. In contrast, PI-PLC-epsilon are activated by both GPCR and RTK. PI-PLC-delta1 and PLC-eta 1 are activated by GPCR-mediated calcium mobilization. The activation mechanism for PI-PLC-zeta remains unclear.	1.1652e-07
NC_011992.1\|WP_012655164.1\|51740_52511_+\|ParA-family-protein	gnl\|CDD\|379293	pfam13614, AAA_31, AAA domain. This family includes a wide variety of AAA domains including some that have lost essential nucleotide binding residues in the P-loop.	1.39195e-86
NC_011992.1\|WP_012655173.1\|60622_61225_+\|NAD(P)H:quinone-oxidoreductase	gnl\|CDD\|179647	PRK03767, PRK03767, NAD(P)H:quinone oxidoreductase; Provisional.	1.54097e-134

>NC_011992.1|WP_012655173.1|60622_61225_+|NAD(P)H:quinone-oxidoreductase
MSKVLVLYYSTYGHLETMAQAVAEGARSAGATVDVKRVPETVPQEIARSAHFKLDQSAPVATVTELENYDAIIVGAPTRFGRMPSQMGSFLDQAGGLWARGALNGKVGAAFTSTATQHGGQETTLFSIITNLLHFGMVIVGLPYSFQGQMTLDEVVGGAPYGATTIAGGQGQRQPSATELDGARFQGRLVAETANKLFGG
>NC_011992.1|WP_012655172.1|59740_60484_+|gamma-glutamylcyclotransferase
MEPHAFRHLPELQGRLTPPQASGLRLTDEVLAAWDAQARQQGLSADWRLPDDVVERSRQAVLAQSEGCDLWVFAYGSLMWNPAIHFDEVRRARLADHARRFALATTIGRGTPDSPGLVLTLQRGVGDCEGLAFRIPQALLERESRMLWRREMIHGSYCPGFQPLHTPQGGVRALVLSANTAHPLHRGGLSLDDTAAIIASAQGSVGSNRDYLDQLACQLDLLGIRDDYVRCLAARVRAHRAAPNRGG
>NC_011992.1|WP_012655171.1|58177_59425_+|MFS-transporter
MPMTTAAPTLRQDARTIGLIGLAHGSSHFFHLLLPPLFPFLIAEFGYSYSELGLLVSVFFVVSGVGQALSGFLVDRVGARPVLFAALASFALAGLTAGSASGYLGLVVASVLAGLGNAPFHPVDFTILNKRVSPARLGHGFSVHGISGNLGWATAPLFMAGIATATGSWRMACLSGGALALVILAIMVWNRDALDDRQGTWAHAPAKGATGSAHAQEHPMAFLKLPAVWLCFSFFFWSTCSLSAIQSFAAPALQRMYDMPLSLTSMVVTGYMLCSAVGMVIGGFLVGRVVRLEKTISICLMASAALLVLVGLGALPGTVALAVAALAGMGVGIAGPSRDMLIKRAAPPGATGRVYGTVYSGLDLGFSVAAPLFGVLLDRGQTADIFYGSALALVLSVVSAALVGGGVARRQAQAA
>NC_011992.1|WP_148215398.1|57197_58028_-|helix-turn-helix-domain-containing-protein
MLSYVESLTPHLFVPSRERPVRAKHRELRADTQVRPHSHPWAQVAISTTGVLRLTVPRGTYIVPPSRALWIPPGVEHAVTMVEDADLRTLYFYQPPGRCGPAVARAQEEPWRQCRVLEVSELLRAVVREMPTDPDDGAPPPPELLHRERHLSALILDELRRASSVRLGVDLPRDKRLRHLCEAVLADPTRHDTLADWARDTGASPRTVARLFRQELGSTFTQWRQQVILARAVALAAGRKPINQIAAELGYNSPSAFSAMVRRAVGLAPGRFLGSP
>NC_011992.1|WP_041838918.1|56556_57132_+|hypothetical-protein
MRIDVDPPDATIEQELSALHQRLHSPGDALHGLPSTPLPGHPGLFVRSRVADGELYVYIEDPLRQCLAGTTVFNRLVELNRRADRHLRAPHSRYAPAYQRRGLATAVYRWALDGGQCLVSGARQSAGAHALWQRLGRDYPQGYVCLQHKTPRYLGRQVDARVQEALATRRLLLGRGWTLARLAAATGMLSA
>NC_011992.1|WP_012655168.1|55130_56171_+|peptidoglycan-binding-protein
MSRKPLTLLAAACAALALTGCETTNMRMGSAESKTVATGAAAGGSAANESGQLERCQSPLGTVSLVENQDAGWYTILRNEYKLPPTANLLRLLIQQSNCFIVVERGAAGMRAMDRERQLMGSGEMRGGSNFGRGQMVASDYGMSPEIIFSNNDAGAIGGVLGGLIGGGSGRALAAVGGGLKTREASAMLTLVDNRSGVQVAASEGSASKSDFAGFGSLFGGSAGGGLGGYQNTAQGKVITAAFMDAYNQMVVALRSYKAQSVQGQGLGGGGRLGVDGGAAPSQTRAGAAMSVREAQERLNAMGYNVGTPDGSAGPKTARALREFQQAQGLPVTGRLDSATAGALSR
>NC_011992.1|WP_012655167.1|54167_54965_+|type-12-methyltransferase
MPRRPRRLHHLHAPPPRRIVLPWPLPAVLVWAAAWLLFAGLRGSVAPLAALGLACAVGVAGSLLAQGWWRRGLIALGFPLSAALGGAVALPAWGWLLPLALLLLVYPLNAWRDAPLFPTPPGALHGLQDAVPLSAGAPVLDAGCGLGDGLKALRAAYPQARLHGLEWSGPLALLCRLRCPWARVRRGDIWATDWGGYDLVYVFQRPESMARVAAKARAEMAPGRWLVSLAFAVPGVRPSARLDSFAGHAVWIYQLPLPADSAAPH
>NC_011992.1|WP_012655166.1|53146_54142_+|ParB/RepB/Spo0J-family-partition-protein
MVTKKPKGLGRGLEALLGPKVADKAPAGANAAGAADGPVSTLALDRLVPGIYQPRTRMDEGALYELAESIKAQGIMQPILVRRLDDEQAQQRRQERASQGASAAMGALSASGPLYEIIAGERRFRASRLAGLAEVPVLVRDVPNEAAAAMALIENIQREDLNPLEEAQGLQRLIREFGLTHELAAQAVGRSRSAASNLLRLLNLAEPVQTMLMAGDIDMGHARALLSLERAAQITAGNQIAAKKLSVREAESLVKKLGAEFALTPQKPKKDKSRDLKRVEEELSDLLMAEVEVRVKKRVKRGSRVEEMGELAIQFGSLEALNGLIERLRGG
>NC_011992.1|WP_012655165.1|52597_53140_+|serine-hydrolase-family-protein
MNPSQILLLPGWQNSGPGHWQTEWERLHGYQRVQQHDWMRPLRGDWSARLEEVVADAPGEVVLAAHSLGCILTAWWAAHTRYAHKVRGALLVAPGDVERPDLAAQIPGWAPIARQVLPFPAVLVGSQDDPYCSFERAQTLAGAWGARFVDCGPRGHINADSDLGEWPEGHALLRALMNKD
>NC_011992.1|WP_012655164.1|51740_52511_+|ParA-family-protein
MAKIFCIANQKGGVGKTTTSVNLAAGLAKIGQRVLLVDLDPQGNATMGSGVDKRALELSVYDVLLESASVPEAAVLSEQCGYRVLGANRELAGAEVELVPLEQRERRLKAALAAVDSDYDFVLIDCPPSLSMLTLNGLCSAHGVIVPMQCEYFALEGLTDLVNTIKQVHANLNPDLQIIGLLRVMFDPRITLQSQVSEQLKDHFGDKVFDTVIPRNVRLAEAPSYGLPGVVFDPAAKGSQAFVEFAREMVERVKRM
>NC_011992.1|WP_012655174.1|62518_62827_-|CRISPR-associated-endonuclease-Cas2
MRMLVFFDLPVVSKADRRAYTVFRRFLLNDGYDMIQFSVYGRILNGTDAAQKHMQRLLANLPSEGSVRVLTVTEKQFASMKLLVGLPLFQEKKVNAAQIALF
>NC_011992.1|WP_148215399.1|62863_63757_-|type-II-CRISPR-associated-endonuclease-Cas1
MVINRPAKLKREHFALVVEQEQSARVPFEDIAVIVLNHREITLTHPVLSACGEYGIGLYSTGDNHQPNGVFMPFLQHSRATRMQRLQLDLDKPSAKRAWAHIVQVKIGNQARCMELLGTVGTDRLASYARRVRSGDGGNLEAQASAYYFPQVFGRSFHRSQTGWSNAALDYGYAVMRGACARALVAHGMLPSLGLFHRSEQNAFNLADDLIEPYRPVVDLHVAQHRPADEDAELQPSDKVALVGLLNVDVAMPRGQMSVLASIEQAAESLARLYDGGSEQVLELPRLIGLRQHVFEI
>NC_011992.1|WP_012655176.1|63758_67154_-|type-II-CRISPR-RNA-guided-endonuclease-Cas9
MAQHVFGLDIGIASVGWAILGEQRIIDLGVRCFDKAETAKEGDPLNLTRRQARLLRRRLYRRAWRLTQLSRLLKRKGLIADAKLFAKAPSYGDSAWELRRQGLDRLLTPLEWARVIYHQCKHRGFHWTSKAEEAKADSDAEGGRVKQGLAHTKALMQAKNYRSAAEMVLAEFPDAQRNKRGQYDKALSRVLLGEELALLFATQRRLGNPHASDFFEKLILGDGDRKSGLFWQQKPALSGADLLKMLGKCTFEKGEYRAPKASFSVERHVWLTRLNNLRIVVDGRSRPLNEAERQAALLLPYQTETSKYKTLKNAFIKAGLWGDGVRFGGLAYPSQAQIDAEKTKDPEDQFLVKLPAWHELRKAFKAAGHEALWQQISTPALDGDPTLLDQIATVLSVYKDGAEVVQQLRQLALPEPAASIAVLEKISFDKFSSLSLKALRRIVPLMQSGLRYDEAVAQIPEYGHHSQRIEPGAAKHLYLPPFYEAQRKYAGKGDHIGSMQFRDDADIPRNPVVLRALNQARKVVNALIREYGSPIAVNIEMARDLSRPLDERNKVKRAQEEFRDRNDRARSEFERDFGYKPKAAAFEKWMLYREQLGQCAYSQQPLDIQRVLDDHNYAQVDHALPYSRSYDDSKNNKVLVLTHENQNKGNRTAFEYLTSFPDGEDGERWRTFVAWVQGNKAYRMAKRNRLLRKNYGVDESKGFIDRNLNDTRYICKFFKNYVEEHLQLAARADGDTARRCVVVNGQLTAFLRARWGLTKVRGDSDRHHALDAAVVAACTHGMVKALADYSRRKEISFLQEGFPDPETGEILNPAAFDRARQHFPEPWTHFAHELKARLFTDDLAALREDMQRLGSYTTEDLGRLRTLFVSRAPQRRSGGAVHKETIYAQPESLKQQGGVIEKILLTSLKLQDFDKLLNPESNDHFVEPHRNERLYAAIRQRLEQFGGRADKAFGPDNLFHKPDKNNQPTGPVVRSIKLVRGKQTGIPIRGGLAKNDSMLRVDIFTKAGKFHLVPVYVHHRVTGLPNRAIVAFKDEDEWTLIDESFAFLFSVYPNDYVKVTLKKEQQSGYYSGADRSTGAMNLWAHDRAASVGKDGLIRGIGVKTALSVEKFNVDVLGRIYLAPPETRSGLA
>NC_011992.1|WP_012655177.1|67349_68774_-|FAD-binding-protein
MNAPATTAHLQPLTTPRPVPQAMLDALAARFGAQYSAAQAVCEQHGRDEGSLQAPPPAAVVFAENTQDVQDAVRLAAQYGVPVIPYGAGSSLEGHLLAVQGGISIDMGRMNRVLSVDADDLTVTVQPGITRKQLNEAIKDTGLFFPIDPGADASIGGMAATRASGTNAVRYGTMRENVLALEVVTASGEVIRTGTRAKKSSAGYDLTRLMVGSEGTLGLFTEVTVRLYPLPEAVSAAICSFPTIEAAVRTVIQTIQLGVPIARVELIDANSVRMVNAHSKLRLREEPLLLMEFHGSPAGVQEQAEVVQDIAREWDGNAFEWATTPEERTRLWTARHNAYFAAVQSRPGCKAISTDTCVPISRLADCLLDSVAEADASGIPYFLVGHVGDGNFHFGYLLDPAVTAERETAERLNHQLVARALRLGGTCTGEHGVGVHKMGFLVDEAGEGAVEMMRAIKRALDPQNILNPGKIFAL
>NC_011992.1|WP_012655178.1|69025_69406_-|calcium-binding-protein
MPHTPQRRTLPSFDARSVMLFAALTVGGAAAQAQTPSAPSAQPQYQTGPGPATTQPKATFGGSSTATPSGSSASASAFERADANRDGQLSSAEAGQLPAIANRFQALDKDKNGSLSRTEFEAGSRS
>NC_011992.1|WP_012655179.1|69561_70134_+|cob(I)yrinic-acid-a,c-diamide-adenosyltransferase
MGNRLTQIATRTGDDGSTGLGDNTRVSKASGRPQAMGDVDELNSHIGLLLCEPLPADMRELLIDVQHQLFNLGGELSMPGYELLKDDALLQLDNALARYNAELPRLLEFILPAGTRAACQAHVCRTVARRAERAVVALQQHETMRAAPRQYLNRLSDLLFVLSRALNRMDGGSEVYWKSERLARQNDATE
>NC_011992.1|WP_012655180.1|70492_70915_-|hotdog-fold-thioesterase
MTLWKKPTTLALITASSANTAVSHLGIEFTEVGDDFLRARVPVDERTRQPFGLLHGGVSVVLAETLGSVGAYHASPEGWLAVGLDINANHLRAARSGWVTGTARPVHIGKTTQVWQIDMVNDAGELTCVSRITMAMLAPK
>NC_011992.1|WP_012655181.1|71138_72296_+|ABC-transporter-substrate-binding-protein
MQRRQFVLQAGRAAALAAAPAFVLPARAQDAPGVSAKALSIGCSAAMSGPLLGFGTDIQLGAGAAFAQANARGGVHGRTLQLQMVDDAYDPERTLANVKQIIGQGSALALLSCVGTPNNTAIVPLVEEAGIPYVAPITGASSLRKSTRNVFHVRASYTDEVQRLIQRLAGMGLKGIGVVYLDNGYGREMLEDATRALAALNMKPAVQVAVATDGKNLPQVLQAVAAARPSAVLLATAGTVSVGLVRGIKKESPGVLMAGLSVTLPSASVGQLGEDGSGLALSMIVPDPNRAKLQLVRDYQSAMRAQVKSEFSQGSLEAYVNARVLIEGLDRAGKDVTQPKLRAALAGIRNLDLGGFVVDYSGQAPYVGSRFIDLGVLGSTGRFIA
>NC_011992.1|WP_041838768.1|72542_74009_-|acetyl-CoA-hydrolase/transferase-family-protein
MSAAEAAALIPAGANIGMSGFTGAGYPKQVPQALAARIEAEHAAGRPFQVNVWTGASTAPELDGALAKVNGIHQRLPFQSDPICRDKINAGEVHYLDIHLSHVAQHAWFGFLGPMQVAVVEVLGILPDGRLIPSAAVGNNKTWLEIADKVILEVNSLPPIEMEGMHDIYYGTAIPPRRQPIHLTQATERIGEPYLRVDPSKVIAVVQTHQRDRDTAFAKPDAVSNQIAAHIIDFLAHEVKVGRLPKNMLPLQSGVGNVANAVLTGLLDGPFDELLGFTEVLQDGMLELIKRGKMTAASATAISLSSEALKDFNEHIAFYRDRIVLRPQEISNHPELVRRLGVIAMNAMIEADIYGNINSTHVMGSAMMNGIGGSGDYARNGYLSFFVTPSVAKGGKVSCIVPMVSHVDHTEHDTQIIVTEQGLADLRGLSPRQRAQVIIDKCAHPDFRPLLQDYFDRARSKGAQHTPHILGEALSWHERCLATGSMLP
>NC_011992.1|WP_012655183.1|74262_74994_+|zf-TFIIB-domain-containing-protein
MPFTPLCPSCRQPTEIRRFAASTGGTLELDLCFACQGMWFDPQENTRLAPAAVLELFELLHQHRGDAHHPLADRLRCPRCSQALAKGYDVAQGGRYVTYRCAARHGRFSTFGSFMVEKGFVRHLSTMEIEALAERVGTINCTSCGGTVDIRHDHACPYCRSALSLLDPQAVDKALARHGSAARQTAPADAASPDALADALVALERNRAREERARQRERLEGTRSDEFDLLTAGIEMVWSLLRR

You can click texts colored in the table to view more detailed information

Click the colored protein region to show detailed information

Crispr_ID: NC_011992_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_011992_2

710011-710112

Orphan

Consensus_repeat	Method
AGCCCCGCCGCTGCACGCAGCGC	CRISPRCasFinder

1 spacers

The CRISPR arrays of NC_011992_2

>merge|NC_011992|2|710011-710112|CRISPRCasFinder
AGCCCCGCCGCTGCACGCAGCGCCTGGGCTTTGTGCCGCAAGGCTGCCGCACCCGCTGGCGCGGGTCGCCGTGCCTTACAGCCCGGCCGCTGCACGCAGCGC

>NC_011992|2|2|710011-710112|CRISPRCasFinder
AGCCCCGCCGCTGCACGCAGCGC	CTGGGCTTTGTGCCGCAAGGCTGCCGCACCCGCTGGCGCGGGTCGCCGTGCCTTAC
AGCCCGGCCGCTGCACGCAGCGC

Protein	Signature genes	Signature genes Name	Protein_function
NC_011992.1\|WP_012655322.1\|713238_714327_+\|IS5-like-element-ISDisp1-family-transposase	unknown	unknown	gnl\|CDD\|377531
NC_011992.1\|WP_187148598.1\|709736_709877_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|236717
NC_011992.1\|WP_012655684.1\|711399_712275_+\|lysophospholipid-acyltransferase-family-protein	unknown	unknown	gnl\|CDD\|236348
NC_011992.1\|WP_011804154.1\|709117_709303_-\|DUF1328-domain-containing-protein	unknown	unknown	unknown
NC_011992.1\|WP_012655679.1\|707103_708138_-\|bifunctional-nicotinamide-nucleotide-adenylyltransferase/Nudix-hydroxylase	unknown	unknown	gnl\|CDD\|235436
NC_011992.1\|WP_012655691.1\|720682_721681_+\|protein-methionine-sulfoxide-reductase-catalytic-subunit-MsrP	unknown	unknown	gnl\|CDD\|235431
NC_011992.1\|WP_049760590.1\|715492_716215_-\|YihA-family-ribosome-biogenesis-GTP-binding-protein	unknown	unknown	gnl\|CDD\|234770
NC_011992.1\|WP_012655676.1\|701787_703404_+\|glucose-6-phosphate-isomerase	unknown	unknown	gnl\|CDD\|234679
NC_011992.1\|WP_012655686.1\|714514_715444_-\|alpha/beta-hydrolase	unknown	unknown	gnl\|CDD\|235628
NC_011992.1\|WP_012655690.1\|719256_720591_+\|c-type-cytochrome-biogenesis-protein-CcsB	unknown	unknown	gnl\|CDD\|274447
NC_011992.1\|WP_012655692.1\|721680_722340_+\|sulfoxide-reductase-heme-binding-subunit-YedZ	unknown	unknown	gnl\|CDD\|235452
NC_011992.1\|WP_012655675.1\|700840_701791_+\|transaldolase	unknown	unknown	gnl\|CDD\|235381
NC_011992.1\|WP_012655685.1\|712271_713144_+\|lipid-A-biosynthesis-acyltransferase	unknown	unknown	gnl\|CDD\|180770
NC_011992.1\|WP_012655677.1\|703434_704601_-\|GGDEF-domain-containing-protein	unknown	unknown	gnl\|CDD\|143635
NC_011992.1\|WP_012655678.1\|704871_706512_-\|chaperonin-GroEL	unknown	unknown	gnl\|CDD\|234573
NC_011992.1\|WP_012655674.1\|699169_700645_-\|glucose-6-phosphate-dehydrogenase	unknown	unknown	gnl\|CDD\|235579
NC_011992.1\|WP_012655689.1\|717106_719260_+\|cytochrome-c-biogenesis-protein-ResB	unknown	unknown	gnl\|CDD\|377471
NC_011992.1\|WP_012655688.1\|716299_716938_+\|c-type-cytochrome	unknown	unknown	gnl\|CDD\|225418
NC_011992.1\|WP_012655680.1\|708193_709051_-\|cysteine-hydrolase	unknown	unknown	gnl\|CDD\|238493
NC_011992.1\|WP_011804151.1\|706602_706893_-\|co-chaperone-GroES	unknown	unknown	gnl\|CDD\|178988

Protein	Function_ID	Function_description	E-value
NC_011992.1\|WP_012655322.1\|713238_714327_+\|IS5-like-element-ISDisp1-family-transposase	gnl\|CDD\|377531	pfam05598, DUF772, Transposase domain (DUF772). This presumed domain is found at the N-terminus of many proteins found in transposons.	2.47886e-30
NC_011992.1\|WP_012655676.1\|701787_703404_+\|glucose-6-phosphate-isomerase	gnl\|CDD\|234679	PRK00179, pgi, glucose-6-phosphate isomerase; Reviewed.	0
NC_011992.1\|WP_187148598.1\|709736_709877_-\|hypothetical-protein	gnl\|CDD\|236717	PRK10572, PRK10572, arabinose operon transcriptional regulator AraC.	0.000157405
NC_011992.1\|WP_012655684.1\|711399_712275_+\|lysophospholipid-acyltransferase-family-protein	gnl\|CDD\|236348	PRK08905, PRK08905, lysophospholipid acyltransferase family protein.	2.91842e-116
NC_011992.1\|WP_012655686.1\|714514_715444_-\|alpha/beta-hydrolase	gnl\|CDD\|235628	PRK05855, PRK05855, SDR family oxidoreductase.	6.88629e-24
NC_011992.1\|WP_012655679.1\|707103_708138_-\|bifunctional-nicotinamide-nucleotide-adenylyltransferase/Nudix-hydroxylase	gnl\|CDD\|235436	PRK05379, PRK05379, bifunctional nicotinamide-nucleotide adenylyltransferase/Nudix hydroxylase.	1.35377e-143
NC_011992.1\|WP_012655691.1\|720682_721681_+\|protein-methionine-sulfoxide-reductase-catalytic-subunit-MsrP	gnl\|CDD\|235431	PRK05363, PRK05363, protein-methionine-sulfoxide reductase catalytic subunit MsrP.	0
NC_011992.1\|WP_049760590.1\|715492_716215_-\|YihA-family-ribosome-biogenesis-GTP-binding-protein	gnl\|CDD\|234770	PRK00454, engB, GTP-binding protein YsxC; Reviewed.	1.28358e-93
NC_011992.1\|WP_012655675.1\|700840_701791_+\|transaldolase	gnl\|CDD\|235381	PRK05269, PRK05269, transaldolase B; Provisional.	0
NC_011992.1\|WP_012655690.1\|719256_720591_+\|c-type-cytochrome-biogenesis-protein-CcsB	gnl\|CDD\|274447	TIGR03144, cytochrome_c_biogenesis_protein_chloroplast, cytochrome c-type biogenesis protein CcsB. Members of this protein family represent one of two essential proteins of system II for c-type cytochrome biogenesis. Additional proteins tend to be part of the system but can be replaced by chemical reductants such as dithiothreitol. This protein is designated CcsB in Bordetella pertussis and some other bacteria, resC in Bacillus (where there is additional N-terminal sequence), and CcsA in chloroplast. We use the CcsB designation here. Member sequences show regions of strong sequence conservation and variable-length, poorly conserved regions in between; sparsely filled columns were removed from the seed alignment prior to model construction. [Energy metabolism, Electron transport, Protein fate, Protein modification and repair].	6.59271e-85
NC_011992.1\|WP_012655692.1\|721680_722340_+\|sulfoxide-reductase-heme-binding-subunit-YedZ	gnl\|CDD\|235452	PRK05419, PRK05419, protein-methionine-sulfoxide reductase heme-binding subunit MsrQ.	3.26746e-71
NC_011992.1\|WP_012655685.1\|712271_713144_+\|lipid-A-biosynthesis-acyltransferase	gnl\|CDD\|180770	PRK06946, PRK06946, lipid A biosynthesis lauroyl acyltransferase; Provisional.	5.87775e-82
NC_011992.1\|WP_012655677.1\|703434_704601_-\|GGDEF-domain-containing-protein	gnl\|CDD\|143635	cd01949, GGDEF, Diguanylate-cyclase (DGC) or GGDEF domain. Diguanylate-cyclase (DGC) or GGDEF domain: Originally named after a conserved residue pattern, and initially described as a domain of unknown function 1 (DUF1). This domain is widely present in bacteria, linked to a wide range of non-homologous domains in a variety of cell signaling proteins. The domain shows homology to the adenylyl cyclase catalytic domain. This correlates with the functional information available on two GGDEF-containing proteins, namely diguanylate cyclase and phosphodiesterase A of Acetobacter xylinum, both of which regulate the turnover of cyclic diguanosine monophosphate. Together with the EAL domain, GGDEF might be involved in regulating cell surface adhesion in bacteria.	3.30115e-59
NC_011992.1\|WP_012655678.1\|704871_706512_-\|chaperonin-GroEL	gnl\|CDD\|234573	PRK00013, groEL, chaperonin GroEL; Reviewed.	0
NC_011992.1\|WP_012655674.1\|699169_700645_-\|glucose-6-phosphate-dehydrogenase	gnl\|CDD\|235579	PRK05722, PRK05722, glucose-6-phosphate 1-dehydrogenase; Validated.	0
NC_011992.1\|WP_012655689.1\|717106_719260_+\|cytochrome-c-biogenesis-protein-ResB	gnl\|CDD\|377471	pfam05140, ResB, ResB-like family. This family includes both ResB and cytochrome c biogenesis proteins. Mutations in ResB indicate that they are essential for growth. ResB is predicted to be a transmembrane protein.	5.41792e-104
NC_011992.1\|WP_012655688.1\|716299_716938_+\|c-type-cytochrome	gnl\|CDD\|225418	COG2863, COG2863, Cytochrome c553 [Energy production and conversion].	5.49918e-25
NC_011992.1\|WP_012655680.1\|708193_709051_-\|cysteine-hydrolase	gnl\|CDD\|238493	cd01011, nicotinamidase, Nicotinamidase/pyrazinamidase (PZase). Nicotinamidase, a ubiquitous enzyme in prokaryotes, converts nicotinamide to nicotinic acid (niacin) and ammonia, which in turn can be recycled to make nicotinamide adenine dinucleotide (NAD). The same enzyme is also called pyrazinamidase, because in converts the tuberculosis drug pyrazinamide (PZA) into its active form pyrazinoic acid (POA).	1.38832e-11
NC_011992.1\|WP_011804151.1\|706602_706893_-\|co-chaperone-GroES	gnl\|CDD\|178988	PRK00364, groES, co-chaperonin GroES; Reviewed.	1.26852e-53

>NC_011992.1|WP_187148598.1|709736_709877_-|hypothetical-protein
MSTPRALLAAGGAPATVAQELGFEDQRHFHNALRERVAAAPGDSRR
>NC_011992.1|WP_011804154.1|709117_709303_-|DUF1328-domain-containing-protein
MLKYAIIFAIISLIAGALGFTGVAAGSAAIAKVLFVVFLVLAVLFVVLALLGIGAARKAIK
>NC_011992.1|WP_012655680.1|708193_709051_-|cysteine-hydrolase
MTRTVHLLAIDPQNDFCDLPAAWHSRDPHSGAVTAPALPVPGAHADMQRLAAFIRAQGAGIDHITVTLDSHQRYDVAHPAYWQRSDGGAVAPFTAITAAQVRAGAFAPRDPAALARTLDYLDTLETQGRYTLMVWPVHCEIGSWGHGVHTDVLAACSDWQAHRLRAVQSVFKGMSPWTEHYSAVQAEVPDAADPHTALNTHLLDQLASADLLLIAGEASSHCVRATTEHIIQHLARLHPGWSPRRLVLLTDCMSPVAGFEAQHEAFLEAMHAQGARLATSSEICL
>NC_011992.1|WP_012655679.1|707103_708138_-|bifunctional-nicotinamide-nucleotide-adenylyltransferase/Nudix-hydroxylase
MYDTAILIGRFEPVHTGHLALLREALVQARQVIVIVGSAFQARTPKNPFTWHEREAMLRGALPEGDRTRLTVLPVRDYYNEAVWVEAVRNAVARHSPPQARVGLVGHFKDATSSYLSAFPGWELIRMERQGRIDATAIRDAYFGATPATVAHALQPLAPMLPPATQALLEQFAHTPHFATLQQEWQMLRGYRAAWATAPYPPVFVTVDAVLRCQDHVLLIRRAHAPGRGLLAVPGGFIEQRETLWQSCLRELAEETNCALPEATLRAALRSVTVFDHPDRSQRGRTITHAHYFDLQDAPLPPVQAADDAAHAEWVAIDRLAGMEEAFFEDHFHMLDHFLRLTVH
>NC_011992.1|WP_011804151.1|706602_706893_-|co-chaperone-GroES
MNLRPLHDRVIVKRIESETTTASGIVIPDNAAEKPDQGEVLAVGPGKKNDKGELIALNVKVGDRVLFGKYSGQTVKVNGDELLVMKEDDLFAVVEK
>NC_011992.1|WP_012655678.1|704871_706512_-|chaperonin-GroEL
MAAKDVVFGGEARARMVEGVNILANAVKVTLGPKGRNVVLERSFGAPTVTKDGVSVAKEIELKDKLQNMGAQLVKEVASKTNDIAGDGTTTATVLAQAIVREGSKYVAAGLNPMDLKRGIDKAVVALVEELKKASKATTTSKEIAQVGSISANSDESVGKIIADAMDKVGKEGVITVEDGKSLENELDVVEGMQFDRGYLSPYFINNPEKQSAILDNPFVLLFDKKISNIRDLLPTLEQVAKASRPLLIIAEEVDGEALATLVVNTIRGILKVVAVKAPGFGDRRKAMLEDIAILTGGKVIAEEVGLTLEKVTLADLGQAKRIEVGKENTTIIDGAGAAADIEARVKQIRIQIEEATSDYDREKLQERVAKLAGGVAVIKVGAATEVEMKEKKARVEDALHATRAAVEEGIVAGGGVALLRAKQAVGNLSTGNPEQDAGIKLVLKAVEAPLREIVANAGGEPSVVVNEVLNGKGNYGFNAANDTYGDMLEMGILDPTKVTRTALQNAASVASLLLTTEAMVAEAPKDESAAPAMPGGMGGMGDMGM
>NC_011992.1|WP_012655677.1|703434_704601_-|GGDEF-domain-containing-protein
MHTTSRRLFPCILSRAPYRRVRVGMALLALLLMSSSALVMLLLHHPSANHHLDAVRWWAALSVGGLAVITLLIRTGWSERLRDPSLTLVQMAWTITSGAVAYVLAGEGRGVVPSVLAMILFFGALGLSPRQVVGIGLYAMAAFSVAVVVSPRFYATTFDVMDGAYAAMILIVLAGCMVVNLRVQQMRQRLDRQREALAEALAENRALAMRDELTGLYNRRAMVELIQLECRRRRRGQGALLFAMIDVDHFKRVNDHHGHAMGDHVLRVFADALRANVRETDVLARWGGDEFLLLLSDIEPRSAQTLLERTREAIAALPVPNAPPDLRLSMSAGLALHLPHSSPQETLERADQALYAAKDQGRNRVALAPELQPAPVDDAPAMPQAARA
>NC_011992.1|WP_012655676.1|701787_703404_+|glucose-6-phosphate-isomerase
MNFDDPRTRCDHTTAWQRLRAHYESAGRSFDLRAAFAQDAQRFERFSQDAPHVFADLSKNLIDAPTEALLLQLARECGVVAYRDAMFEGRPINNTEQRAVMHWLLRKPAPGHTGQARVAIDTVAPEIASALHDVHAMLEDMLALAERVRADDGITDIVNIGIGGSDLGPAMVVKALDDLRHPGKRLHFISNVDGMELGSLLRQLRPESTLFLIASKTFTTAETMSNAQAARAWFLDQGGSEDARARLPLARHFYALTTNLEAAAQFGITTTLGFWDWVGGRYSLWSAIGLPIAIAVGAPHFRALLAGAHAMDEHFRTAPLESNLPVRLALLDLWYRNFHDFSSRSMAPYSHGLRRLPAYLQQLEMESNGKGVDAHGQPLPYATSAVVWGEPGTNGQHAFFQMIHQGPDTVPVEFIALREPGRDLPDQHPRLVANALAQARALMMGRPEEADGHRRFSGNRPSTFLVLERLDPASLGALIALYEHRVFTSGALWGINSFDQWGVELGKGIAKDLEPRLATGDVQGLDPSSAGLLRRLAA
>NC_011992.1|WP_012655675.1|700840_701791_+|transaldolase
MNQLDALKQYTTVVADTGDFKQLAQFQPQDATTNPSLILKAVQKPEYAPLLKDCVTRWHGRAIDELMDRLIVRFGCEILSIIPGRVSTEVDARLSFDTAATVARAERIVELYQAEGLHIDRVLIKIAATWEGIQAARQLEQRGIHTNLTLLFSFAQAVACGQAKVQLISPFVGRIYDWYKKQAGANWDEAAMAGANDPGVQSVRAIYNHYKHFGIGTEVMGASFRNTGQIVALAGCDLLTIAPELLAQLAASDAPVARVLDPEAARRVALQPVQYDEAGFRYALNADAMATEKLAEGIRAFAADAAKLEQLMQAAA
>NC_011992.1|WP_012655674.1|699169_700645_-|glucose-6-phosphate-dehydrogenase
MSFDLVLFGGTGDLAWRKLLPALFQAFRHGSLPPQGRIIGVARDALSDGDYRALIARRFADVEGEKRPSDEEFERFAALLQYQRMDLSQPEDYALLARRLHERHADTVVMYLATAPALFTTVCEQLGAAGLATPATRVVLEKPLGHDLASNRAINAAVRSVFDERQIFRIDHYLGKPSVQNLLALRFGNALFEPLWRRETVASIEITMAEQLGVEQRGAFYDQTGALRDMVQNHALQLLCAIAMEPPINAHADAIRDEKLKVLRSLSTWTPATLLRDVVRGQYSTGTTACEGVRAYADEDGVAPGSTTETFVALRTEIANWRWAGVPFYIRTGKRLAAREAHIAINFRPTPHAIYRTPLGAANRLVIHLQPRDGLALHLFAAGQEKRGMRISEAQALAPVQLDLDFDQRFGSQRVGAYERLLLDVIAGRLNLFVRADEQEAAWHWVEPIMQAWAEQDARGEGPRPYAAGSWGPSAASALVAREGHTWMEEC
>NC_011992.1|WP_012655684.1|711399_712275_+|lysophospholipid-acyltransferase-family-protein
MSSLFRLVSALPLWLLHVIGAALGWVAFCASPTYRRRFIDNAARAGYALRDVRAAIAHAGRMVAEAPRLWLRPEPPACEIHGAECVQRAWGQGRGIVFLTPHIGCFELSVQAAARRWSPEHGPITILYRPARQRWLAEVMQTARNRPGIQAVPTTLQGVRQMIKALRRGEAVGLLPDQVPPQGLGVWSPFFGRPAYTMTLAARLVQQTGAAVILARCERLPRGRGYVLHLEDLPQPLAPTLDAAVLQLNQAMEYLIRQSPDQYLWGYARYKQPRAEMHTSAGTDAPPEGRA
>NC_011992.1|WP_012655685.1|712271_713144_+|lipid-A-biosynthesis-acyltransferase
MMARAGIALLNLLGRLPLPMLRALGRFIGRVLFVLAVPRRRVALRNLALCFPEVPESQRRAWARESFVVFCQTFLDRGWLWSGSEALVRSRVKLVGALHELEGDTPTIVFAPHFYSMDAGGLALPLNTRREFTSIFATNPDPVLDAWFMAGRQRFGNVRMLNRADGVKPIISCLRKGGLLYLLPDMDYGRNDSVFVPFFAMPDAATIPSLSRFARLGRAKVVALYSRMTPEGYVAELTPAWDHFPTEDHVADTARMNRELEAAIRTMPAQYYWVHKRFKTRPEGQDSVYQ
>NC_011992.1|WP_012655322.1|713238_714327_+|IS5-like-element-ISDisp1-family-transposase
MRGNQDFQGAMFSYISLEERVPQAHPLRKLRAVVDALLATMNREFEAVYARRGRPSVPPEMLLKALLLQILFSIRSERQLVEAINYNLLYRWFVGLNIEDKVWDHSTFSANRERLFNEDLARTFFERVKLSAQWGKLASDEHFSVDGTLIDAWASHKSFKRKDDDSGTPPGRNPEVDFKGQERCNDTHKSTTDADARLFKKSRGDKSRLCHMGHILMENRNGLIVDVEITHASGTAEREAALAMLERRGNRNKRATVGADKGYDSKAFIKGCRKLKVTPHVAAKDKHSAVDARVTRHEGYKTSLKVRKRIEEAFGWIKTVGGLAKTKLIGQAKLTGQALLCFATYNLVRMGSIGGWWNAHHA
>NC_011992.1|WP_012655686.1|714514_715444_-|alpha/beta-hydrolase
MAETITHTLPHGITLHCRVAGMPGRPVLLFLHGFPEGAFIWDALLGHFADPAHGGYRCVAPWLRGYAPSSAPAAIEAYRPKHLVQDIAALIAQEAGAGTPLAALVAHDWGGAVAWNLANQHPGLLKRLMVINAPHPGAFLRELQGSAAQQEASAYMHFLCRPDAESLLAENDFARLFGFFRRADGSAPGWLTPALRAHYRAQWAAGLAGPCNYYRASPLRPPRPASARDVGTPDIRSLTLPADMLQVSVPTQVLWGMEDPALLPGLLQGLQAWVPRLQVLHVPGATHWVVHEQPGLVRDTLADFLRQSL
>NC_011992.1|WP_049760590.1|715492_716215_-|YihA-family-ribosome-biogenesis-GTP-binding-protein
MPTTSHAPVAGSLPPAPDAKVAMGWMHTARFLTTAAQLHHLPAIEVPEIAFVGRSNAGKSTCINTLTQQRQLAFASKKPGRTQHINLFALGKQGATDAVLADLPGYGYAAVSRSDKLRWQQVMLSYLVSRESLTAIVLLCDPRLGLTELDEALLNAVRPRVEAGLKFLVLLTKADKLTRAEQAKALSITRLQAGGGEVRMFSALKKQGVDEVAQLLWQWAHPVQKEDAAVEALPPSKDQN
>NC_011992.1|WP_012655688.1|716299_716938_+|c-type-cytochrome
MKLLASLLMAAALAVPAASALAAGETPAPQKAAKPDLVKGEASYAAVCAACHAADGNSTIAANPKLAQQHPEYLVKQLQEFKAGKRADPIMQGMAAILSEDDMRNVSWWLASKQAKEGFAKDKDLVAMGERIYRGGIQERNIAACAGCHSPNGSGIPAQYPRLSGQHADYTVKQLVDFRDGKRGNNVQMRDVAAKLNDREIKAVADYIAGLR
>NC_011992.1|WP_012655689.1|717106_719260_+|cytochrome-c-biogenesis-protein-ResB
MSDTTFGPSSAPRTHAMRSMTELLASMRFAIALLTVICIASVIGTVLKQHEPAVNYVNQFGPFWADVFLALKLNAVYSAWWFLVILGFLVVSTSLCIARHAPKYLADLRTYKEDIREKSLQAFHHKASAELAAETPEAAARRVGQQLVAKGWKVRLQQRQTPAGDGWMVAAKAGAANKLGYIAAHSAIVLVCLGGLLDGDLVVRAQMWFGGKTPYAGSGLISEVKPEHRLSERNPTFRGNLVVAEGTQSGTAILSQSDGVLLQELPFAVELKKFIVEHYSTGMPKLFASEIVIHDRATGEATPARVEVNHPVSYRGIEIYQSSFDDGGSEVHLRARPMAPGAEPFDVQGVIGGSTRLTHSGSGEGMTLEFTGLRVLNVENFGDTGASGSGADVRKVDLRESIESRLGAGNKTVSKRELRNVGPSITYKLRDAAGQAREFHNFMLPVDTGDGQPMYLLGVRETPAEPFRYLRVPVDAEGGMDGFLRMRLALADPQMRELAVRRYAAAAVDGARPELAEQLAQSAGRALALFAGAIDEPAAAGGRPRGGLQAISDFMEANVPEDERNRASEVLVRILNGALFELAQITRERAGLAPLPQNGATQAFMTQAVLSLSDAQAYPVPLAFELRDFKQVQASVFQVARAPGKNVVYLGCALLIIGVFAMLYVRERRVWVWLAPQDAGARATMALSTNRKTLDADREFAQLTTQLIGTSPHGGAS
>NC_011992.1|WP_012655690.1|719256_720591_+|c-type-cytochrome-biogenesis-protein-CcsB
MNTATTTLTLSEGYFARRSWWDWLFALLVVAGGVFALQRYAAYMDVYEKAILLGSIPSAIWLGWFWRPLSTLMLMVAACSLLAIGLYQNNGAGDLARADTIFGLKYFLSSQSAILWMSMLFFMSTAFYWVGMLSRGQGQTMMRIGSRIAWVAVALALIGTMVRWYESYQIGPDIGHIPVSNLYEVFVMFCWMTAVFYLYYEEQYETRALGGFVMLVVSAAVGFLLWYTVVREAHEIQPLVPALKSWWMKLHVPANFIGYGTFALSAMVAFAYLIKQQASETRWWKLTPLWLLGVVLCFEPIVFRQGAADNGGGYWMVYFGVSALIVAGILLARRRIAERLPSFEILDDVMYKSIAVGFAFFTIATVLGALWAAEAWGGYWSWDPKETWALIVWLNYAAWLHMRLMKGLRGTMSAWWALVGLAVTTFAFLGVNMFLSGLHSYGTL
>NC_011992.1|WP_012655691.1|720682_721681_+|protein-methionine-sulfoxide-reductase-catalytic-subunit-MsrP
MLIPTRDNGYIHPCAGEITPRAVYEQRRAMLRLLAAGAGGAAMAGWAGRVALADQVRRPGRLAPLPGAPSAVPGAVTMEKVTEYQDATTYNNFYEFGTDKSDPARNAHTLKTRPWTVEVEGLVNKPRRFDIDELLKLSAQEDRIYRLRCVEGWSMVIPWVGYSLAELIKRVEPQGSAKYVEFVTLADKATMPYVGSHVLDWPYTEGLRLDEAMHPLTLLAFGMYGEVLPNQNGAPVRIVVPWKYGFKSAKSIVKIRFVEKEPGTAWNKAARQEYGFYSNVNPDVDHPRWSQATERRIGEGGLFAKKRKTLLFNGYEAQVGQLYAGMDLRKFY
>NC_011992.1|WP_012655692.1|721680_722340_+|sulfoxide-reductase-heme-binding-subunit-YedZ
MGHARLSGSTPALAGRGWGARVLLHPAAKPVLFVLCLLPLAWLVYGAAADRLGANPAEALIRSTGDWTLRMLCLTLAVTPLRLALAQPPLARFRRMLGLYTFAYAALHLLCYSWFDMGLDVPEIVRDVLKRPFILVGMGCFAVLLALAATSFNRAMRWMGGRRWQQLHRGVYLAAGLAILHFFWMRSGKNDFAEVAVYAAILAALLLARPWLRRRRRVV

You can click texts colored in the table to view more detailed information

Click the colored protein region to show detailed information

Crispr_ID: NC_011992_3

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_011992_3

1961813-1961891

Orphan

Consensus_repeat	Method
GCTGCACTGCGGCGGCCACCTGCGC	CRISPRCasFinder

1 spacers

The CRISPR arrays of NC_011992_3

>merge|NC_011992|3|1961813-1961891|CRISPRCasFinder
GCTGCACTGCGGCGGCCACCTGCGCACCGACTGGGGCGTGCAGGTGCAGGAATCGCTGCACTGCGGCGGCGACCTGCGC

>NC_011992|3|3|1961813-1961891|CRISPRCasFinder
GCTGCACTGCGGCGGCCACCTGCGC	ACCGACTGGGGCGTGCAGGTGCAGGAATC
GCTGCACTGCGGCGGCGACCTGCGC

Protein	Signature genes	Signature genes Name	Protein_function
NC_011992.1\|WP_015913365.1\|1958946_1961028_+\|TonB-dependent-receptor	unknown	unknown	gnl\|CDD\|238657
NC_011992.1\|WP_015913371.1\|1967497_1968133_-\|GntR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|224715
NC_011992.1\|WP_015913372.1\|1968257_1970420_+\|methylmalonyl-CoA-mutase	unknown	unknown	gnl\|CDD\|236508
NC_011992.1\|WP_015913362.1\|1957403_1957949_+\|peptide-methionine-(S)-S-oxide-reductase-MsrA	unknown	unknown	gnl\|CDD\|237597
NC_011992.1\|WP_015913364.1\|1958367_1958772_+\|hypothetical-protein	unknown	unknown	unknown
NC_011992.1\|WP_015913367.1\|1962451_1963675_+\|chromate-efflux-transporter	unknown	unknown	gnl\|CDD\|273350
NC_011992.1\|WP_015913363.1\|1958102_1958342_+\|hypothetical-protein	unknown	unknown	unknown
NC_011992.1\|WP_015913358.1\|1953002_1953356_+\|DUF3147-family-protein	unknown	unknown	gnl\|CDD\|181745
NC_011992.1\|WP_015913373.1\|1970416_1971445_+\|methylmalonyl-Co-A-mutase-associated-GTPase-MeaB	unknown	unknown	gnl\|CDD\|236515
NC_011992.1\|WP_015913376.1\|1973482_1975531_+\|acetyl/propionyl/methylcrotonyl-CoA-carboxylase-subunit-alpha	unknown	unknown	gnl\|CDD\|227111
NC_011992.1\|WP_015913360.1\|1954065_1955409_-\|TolC-family-outer-membrane-protein	unknown	unknown	gnl\|CDD\|236529
NC_011992.1\|WP_015913370.1\|1965499_1967329_-\|long-chain-fatty-acid--CoA-ligase	unknown	unknown	gnl\|CDD\|223953
NC_011992.1\|WP_015913375.1\|1973019_1973460_+\|PH-domain-containing-protein	unknown	unknown	gnl\|CDD\|369049
NC_011992.1\|WP_187148618.1\|1963739_1964198_-\|Lrp/AsnC-ligand-binding-domain-containing-protein	unknown	unknown	gnl\|CDD\|224439
NC_011992.1\|WP_015913374.1\|1971470_1973003_+\|acyl-CoA-carboxylase-subunit-beta	unknown	unknown	gnl\|CDD\|227136
NC_011992.1\|WP_015913361.1\|1956607_1957273_-\|TetR/AcrR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|224228
NC_011992.1\|WP_015913359.1\|1953400_1953982_+\|dihydrofolate-reductase-family-protein	unknown	unknown	gnl\|CDD\|223340
NC_011992.1\|WP_011805270.1\|1955479_1955818_-\|sulfurtransferase	unknown	unknown	gnl\|CDD\|238786
NC_011992.1\|WP_011805271.1\|1955849_1956560_-\|protein-L-isoaspartate-O-methyltransferase	unknown	unknown	gnl\|CDD\|225316
NC_011992.1\|WP_015913369.1\|1964329_1965499_+\|saccharopine-dehydrogenase-NADP-binding-domain-containing-protein	unknown	unknown	gnl\|CDD\|224662

Protein	Function_ID	Function_description	E-value
NC_011992.1\|WP_015913365.1\|1958946_1961028_+\|TonB-dependent-receptor	gnl\|CDD\|238657	cd01347, ligand_gated_channel, TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel. Energy (proton-motive force) and TonB-dependent conformational alteration of channel (parts of plug, and loops 7 and 8) allow passage of ligand. FepA residues 12-18 form the TonB box, which mediates the interaction with the TonB-containing inner membrane complex. TonB preferentially interacts with ligand-bound receptors. Transport thru the channel may resemble passage thru an air lock. In this model, ligand binding leads to closure of the extracellular end of pore, then a TonB-mediated signal facillitates opening of the interior side of pore, deforming the N-terminal plug and allowing passage of the ligand to the periplasm. Such a mechanism would prevent the free diffusion of small molecules thru the pore.	1.33601e-45
NC_011992.1\|WP_015913371.1\|1967497_1968133_-\|GntR-family-transcriptional-regulator	gnl\|CDD\|224715	COG1802, GntR, Transcriptional regulators [Transcription].	1.52269e-42
NC_011992.1\|WP_015913372.1\|1968257_1970420_+\|methylmalonyl-CoA-mutase	gnl\|CDD\|236508	PRK09426, PRK09426, methylmalonyl-CoA mutase; Reviewed.	0
NC_011992.1\|WP_015913362.1\|1957403_1957949_+\|peptide-methionine-(S)-S-oxide-reductase-MsrA	gnl\|CDD\|237597	PRK14054, PRK14054, peptide-methionine (S)-S-oxide reductase.	3.28391e-100
NC_011992.1\|WP_015913367.1\|1962451_1963675_+\|chromate-efflux-transporter	gnl\|CDD\|273350	TIGR00937, Chromate_transport_protein, chromate transporter, chromate ion transporter (CHR) family. Members of this family probably act as chromate transporters, and are found in Pseudomonas aeruginosa, Alcaligenes eutrophus, Vibrio cholerae, Bacillus subtilis, Ochrobactrum tritici, cyanobacteria and archaea. The protein reduces chromate accumulation and is essential for chromate resistance. [Transport and binding proteins, Anions].	1.39843e-79
NC_011992.1\|WP_015913374.1\|1971470_1973003_+\|acyl-CoA-carboxylase-subunit-beta	gnl\|CDD\|227136	COG4799, COG4799, Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta) [Lipid metabolism].	0
NC_011992.1\|WP_015913358.1\|1953002_1953356_+\|DUF3147-family-protein	gnl\|CDD\|181745	PRK09272, PRK09272, hypothetical protein; Provisional.	2.43017e-40
NC_011992.1\|WP_015913373.1\|1970416_1971445_+\|methylmalonyl-Co-A-mutase-associated-GTPase-MeaB	gnl\|CDD\|236515	PRK09435, PRK09435, methylmalonyl Co-A mutase-associated GTPase MeaB.	0
NC_011992.1\|WP_015913376.1\|1973482_1975531_+\|acetyl/propionyl/methylcrotonyl-CoA-carboxylase-subunit-alpha	gnl\|CDD\|227111	COG4770, COG4770, Acetyl/propionyl-CoA carboxylase, alpha subunit [Lipid metabolism].	0
NC_011992.1\|WP_015913360.1\|1954065_1955409_-\|TolC-family-outer-membrane-protein	gnl\|CDD\|236529	PRK09465, tolC, outer membrane channel protein; Reviewed.	6.42589e-84
NC_011992.1\|WP_015913370.1\|1965499_1967329_-\|long-chain-fatty-acid--CoA-ligase	gnl\|CDD\|223953	COG1022, FAA1, Long-chain acyl-CoA synthetases (AMP-forming) [Lipid metabolism].	1.01661e-165
NC_011992.1\|WP_015913375.1\|1973019_1973460_+\|PH-domain-containing-protein	gnl\|CDD\|369049	pfam06713, bPH_4, Bacterial PH domain. This family consists of several hypothetical proteins specific to Oceanobacillus and Bacillus species. Members of this family are typically around 130 residues in length. The function of this family is unknown. Members of this family have a PH domain like structure.	1.7788e-30
NC_011992.1\|WP_187148618.1\|1963739_1964198_-\|Lrp/AsnC-ligand-binding-domain-containing-protein	gnl\|CDD\|224439	COG1522, Lrp, Transcriptional regulators [Transcription].	1.66633e-32
NC_011992.1\|WP_015913361.1\|1956607_1957273_-\|TetR/AcrR-family-transcriptional-regulator	gnl\|CDD\|224228	COG1309, AcrR, Transcriptional regulator [Transcription].	1.02411e-20
NC_011992.1\|WP_015913359.1\|1953400_1953982_+\|dihydrofolate-reductase-family-protein	gnl\|CDD\|223340	COG0262, FolA, Dihydrofolate reductase [Coenzyme metabolism].	2.86039e-15
NC_011992.1\|WP_011805270.1\|1955479_1955818_-\|sulfurtransferase	gnl\|CDD\|238786	cd01528, RHOD_2, Member of the Rhodanese Homology Domain superfamily, subgroup 2. Subgroup 2 includes uncharacterized putative rhodanese-related domains.	1.35714e-29
NC_011992.1\|WP_011805271.1\|1955849_1956560_-\|protein-L-isoaspartate-O-methyltransferase	gnl\|CDD\|225316	COG2518, Pcm, Protein-L-isoaspartate carboxylmethyltransferase [Posttranslational modification, protein turnover, chaperones].	1.05758e-64
NC_011992.1\|WP_015913369.1\|1964329_1965499_+\|saccharopine-dehydrogenase-NADP-binding-domain-containing-protein	gnl\|CDD\|224662	COG1748, LYS9, Saccharopine dehydrogenase and related proteins [Amino acid transport and metabolism].	6.10723e-82

>NC_011992.1|WP_015913365.1|1958946_1961028_+|TonB-dependent-receptor
MNSFTPFARMPGAMHPLAWAALLCLTSAAPAWAQADARLPEVTVSSSGLQLGVSEMTQPVSVLEGDALVRQREATLGETLDGEPGITGSHFGAGASRPVIRGMDGPRVRVLSDGSELHDASTVSPDHAVAAEPLLATQVEVLRGPSALVYGGGAVGGVVNVLDGKVPTAVPDKGYEGSAELRAGSAAREKAGAVALTGGAGNLAVHVEAAGRDADDYRVGSGWAEGRRVPGSFNRTGTGSVGLSWVGSRGYLGLAFTRQNAKYGLPGHSHSFEGCHTHGNHLHCGSHDEHDHEDDGHDHDHGHEAVPVVDLRSERVDIRGELRDPFTGFSALRLRAGVTDYVHDEVEEGTVATTFKNKAHDLRVELQHEPVAGWRGVLGLQTGQRKFSAAGEEAYVQPTLTRQWGVFLLEEYRLGDWHGDWRIETALRHDRQSAEAQDSGVERRHHGTSASLGAVWRFAPGYAAGASITRAHRAPTAEELYARGLHMATSTYERGDASLRAETSRNIDLSLRKTSGDTTFDVSVFHNRIRNYIYGRTLDELDGLQLLQYSQAGATFTGMEGRVRQRITQRLGVTLFGDSVRARLDGGARLPRIAPARVGLRLDANWRDWDGAVEWVQVARQNRVAAFETATPGYGMLNLGLAYNSRTGSGTPWQVYLKARNLTDRLAYAHTSFIKDAAPLAGRNVTVGVRVSF
>NC_011992.1|WP_015913364.1|1958367_1958772_+|hypothetical-protein
MSLTPALLPQLRRRLALTWLLLALVLAPALGRMHQVLHLPAGQGLAHALHDDGHARDAASAGQQALDTLHALFAGHGAADCQVLDEQTLVGAALGQAPAQVQAQPQLPPARTPAPVPRAGRAAPFHARAPPLSA
>NC_011992.1|WP_015913363.1|1958102_1958342_+|hypothetical-protein
MKPWLATLLLGCAAVAHAQEHTAQQTKVDIERHRAMAAAHEAAAKCLESGKGEETCRKELQAACKNLAIGKYCGMKHAH
>NC_011992.1|WP_015913362.1|1957403_1957949_+|peptide-methionine-(S)-S-oxide-reductase-MsrA
MSDLQSITLGGGCFWCTEAVFDRVRGVTDVQSGYANGDVAEPTYEQVCSGTTGHAEVVRVTFDPAQIGVREILEIFFATHDPTTLNRQGNDVGTQYRSAIYFADPAHQDVAEELLRQMGQDKLFGAPVVTEVAPLVNYWPAEDYHQDYYRNHPNQGYCAFVVGPKVEKFRKTFARHLKPGA
>NC_011992.1|WP_015913361.1|1956607_1957273_-|TetR/AcrR-family-transcriptional-regulator
MAAALPPVPESSEPPRRGRRKEARPGELLDAALDLFVEKGFAATRVDEVAARAGVSKGTLFLYFPSKEDLFKAVVRKNIAGRFPEWDLEMETFEGTSSELVQYCFQTWWERVGSTKASGLGKLMLSEANNFPEIAEFYRREVVEPGHRLIRRILQRGMDRGEFRTLDLDHAVYLVLAPLMFLMFSQPSLSLCIPNPDTFSAQEYIRLQAENVLQGLCVRPT
>NC_011992.1|WP_011805271.1|1955849_1956560_-|protein-L-isoaspartate-O-methyltransferase
MNMPLNTSADICDPTEQARYNMVEQQIRPWNVLDEAVLELLFTVRREEFVPPAYQGAAFIDTQIPLNPSVEEAERLGQVMLAPRVDARMLQDLQVQSTDRVLEIGAGSGYMAALLAARAERVVSLEIVPELAEFARENLRSAGVDNAEVRQSDGALDPIPDGPFDVIVLSGSVAEIPQRLLGLLRDGGRLGAFVGHMPMMRATFVRRQGDRYETTQPWDVVVPRLRHFPEPTRFKF
>NC_011992.1|WP_011805270.1|1955479_1955818_-|sulfurtransferase
MIDHVRPAQLADWLTANAGSRPLVLDVREPWELQTASVTPQGFELVAIPMGELAARLDELDPARPVACLCHHGMRSLRVAGFLAHQGFDQVANITGGIEAWSHERDPAVPRY
>NC_011992.1|WP_015913360.1|1954065_1955409_-|TolC-family-outer-membrane-protein
MTSLQRLLSVSLAVGVCALGALPAQAQSLSTLVEWARSYDAPWQAAQAQLQAADSRAEQARAGLLPSAALNGGVTYARTDLTRGPLPPLDLHAPTQTVGVVASQPLYRPANRIGFEQGQRGIDIARAQRDGAEQDLLVRVSQAYFDVLAAQDTLTFMQAQKAAVAEQLAAAKRNFEVGTATVTDEREAHARHDLVSAQEIAAENDLHVKRLALEQTVGRSGLTPLPLAQPVQLPAVQPADVNSWVHVAEDQQPQVRQAAIALDVARLETAKAETGHLPTVDLQAGYSVQRTPNGTVTMPGVHSRANVASVGVALNLPLFAGFAVQNRVKETLSLEDKARADLDHARRSVAQATRAAFFGVQSGQSQVRALQAAEASTQSALEANQLGYEVGVRINIDVLNAQSQLYQTKRDLAVARYNVLMGTLRLKQAAGTLSMDDVVAVDSLLSR
>NC_011992.1|WP_015913359.1|1953400_1953982_+|dihydrofolate-reductase-family-protein
MKTQYFTATSLDGFLATEDDSLDWLFTLGSLEESSYPAFIAQVGALAMGSSTYEWMLRNADAVRAETGSAWPYTQPAWVFSSRRLPGIDGADIRFVQGDVRPVHAAMRLAAGTKNLWVVGGGDLAGQFYDAGLLDELILQVGSVTLGRGKPLFPRRLPSTALRLLDAQPLGTGMVELRYAVNRTGDPADFDRE
>NC_011992.1|WP_015913358.1|1953002_1953356_+|DUF3147-family-protein
MGWLVTKYLITAAVVVAVSEAAKRSDRLGALLAALPLVTFLALVWLYVEKQPQEKIANHAWYTFWYVVPTLPMFLAFPWLLPRIGFGLTLLASAAITVVCFGLFALAVRPLGVELLP
>NC_011992.1|WP_015913367.1|1962451_1963675_+|chromate-efflux-transporter
MPPISPFAATRHHASAWRVFLIFLRLGLTSFGGPVAHLGYFREEFVARRGWLTEDAYADLVALCQFLPGPASSQVGLALGLRQAGWGGALAAWLGFTLPSALVMALLGLGLVAGQGLVPAGMLHGLKVAAVAVVAQAVWGMARSLCRGPARLLLMVLACALALLWPGVVGQVGAMLVAGLAGLGLWGRAGAMPAPPSQGGLAAGVRPRTGALLLAAFAALLVLLPLAARAWPQGWLVLADAFYRAGALVFGGGHVVLPLLQAEVVATGWVAADDFLAGYGLAQAVPGPLFTFAAFLGAAAGHGAGGWLGAAVCLVAIFVPAFLLVAGALPFWDRLRHNARARAALAGVNAAVVGLLLAALYHPVWTSAIHAPADLALALAAFAALVWARVPPWLVVPLCGAAGWLLG
>NC_011992.1|WP_187148618.1|1963739_1964198_-|Lrp/AsnC-ligand-binding-domain-containing-protein
METPVELDALDQQLLSLLQANAREGTAELARRLGLARTTVVARIARLEREGVVAGYGVRLGQRLAGSAVRAWCALRVLPKAGPAVLQTLQALPQVEEVSAVSGPFDYLVFLRCTSHEQLDGLLDRIGQLDGVQNTQTSIVLSRKIDRRSVGG
>NC_011992.1|WP_015913369.1|1964329_1965499_+|saccharopine-dehydrogenase-NADP-binding-domain-containing-protein
MTRLHPVNASHPHRVLILGAGHIGRAIALLLEDAGSYTLTVADRDAAALKRLQVHSAATLQVTDDAMLEAAIAGHHAVLNALPFHQAVPVATLCARHGVHYFDLTEDVASTRAIQALAEGARSAFMPQCGLAPGFIGVVGNALAQRLDRVEALQLRVGALPRYPQGALRYAMTWSTEGLINEYCNPCDAIVQGRRTSVPALDGLETLLIDGVEYEAFNTSGGLGTLPQTWEGRVRQLDYKSVRYPGHHAILQLLLHELRLRDRRDLLKELLDGAVPTTQQDVIVILASARGQRDGRLVQESYAAHILGASVRGQMLSAIQRTTAAGICAALDLVIAGQLPQAGFIGQEQIALEDFLANRFGRVYRVPGSEGDAGSAQAPLARSLQAVGA
>NC_011992.1|WP_015913370.1|1965499_1967329_-|long-chain-fatty-acid--CoA-ligase
MNSSTPDLRGVQTLPELLAFRAALTPHSEAYRACDPGTGQWISLTWAQTQERVQQWGRAIAASGLPQGARIAILLPNGLDAMSIDQAVMATGCVPVPLHAIDNPGSIAYILADAEVSLLVVEEPEQWRRIRDVGMPLPHLMGVVTTNASTGLPTAAEQDVPVAPLAAWLQHAAADTPLPPPPGPEDLAAIVYTSGTTGKPKGVMLSHANVVADVKAVLERIAPTPQDVFLSFLPLSHTFERTGGYYLPMASGSCVVYARSVAQLAEDLKNVRPTVLVSVPRIYERVHAKLIETLSPSPLKMQLFQAAQAVGWKRFCAAQRLPAPQDDGAGGWMRALPWPLLRALVAKPLLAQFGGRVRVAVSGGAPLSPTIAHCFLGLGLQLVQGYGMTETTPVVSVNTLEDNDPSTVGRALPGVEVRIGENRELQVRGPIVMKGYWKRPEDTARTVSADGWLGTGDQAEIVDGRIRILGRIKEIIVTSTGEKVPPADLELAITADALFEQAFVVGEQRPFIACVAVVHAEEWRQLAGQLGLDANDPASLAHPSAQRAALARIEKLAAGFPRYAVPRAVHLVREPWTIENAFMTPTLKLKRTNLMAHYAAAIEAMYQKR
>NC_011992.1|WP_015913371.1|1967497_1968133_-|GntR-family-transcriptional-regulator
MSAVTLTPRALYEQVAEQLRQRIFRRELEPGSWIDELKIAEEFGISRTPLREALKVLAAEGLVTMKVRRGAYVTEMSDKDLHDVYHLLSLLESDAAGVVAARATPEQLRELEQLHADLAAAVQDRDRFFTINERIHMRLLEMADNRWRSQMVADLRKVMKLNRHNSLLKQGRIEDSLAEHETILAALRARDPQATVAAMSAHFAHGLEAAG
>NC_011992.1|WP_015913372.1|1968257_1970420_+|methylmalonyl-CoA-mutase
MSSHPDPIFQSADLAAWAKAAAKSAPGGDVNALNWVTPDGISVKPLYTAQDTQDLPYANTLPGFEPYLRGPQATMYAVRPWTIRQYAGFSTAEESNAFYRKALAAGGQGVSVAFDLATHRGYDSDHPRVTGDVGKAGVAIDSVEDMKILFDGIPLDKVSVSMTMNGAVLPVLAGYVVAAEEQGVSQDKLAGTIQNDILKEFMVRNTYIYPPKPSMRIIGDIIEYTSKNMPKFNSISISGYHMQEAGANQALELAFTLADGKEYVKTAIAKGMDVDDFAGRLSFFWAIGMNFYLEIAKMRAARLLWCRIMKGFNAKNPKSLMLRTHCQTSGWSLTEQDPYNNVVRTTIEAMAAVFGGTQSLHTNALDEAIALPTEFSARIARNTQLIIQEETHITNVIDPWAGSYMMEKLTQDMADAAWKIIEEVEAMGGMTAAVDSGWAKLKIEAAAAEKQARIDSGKEVIVGVNKYKLAKEDPVDILEVDNVKVRENQIARLNAIKAKRDQSAVDQALAALTSAAESGQGNLLDLSIQAIRARATVGEVSDALEKIFGRHRADTQKVTGVYAAAYDSAEGWEKLKGEIDQAAEQLGRRPRVMIAKLGQDGHDRGAKVVATAFADLGFDVDMGPLFQTPEECARQAIENDVHAVGVSTLAAGHKTLVPAIIEELKKQGADDIIVFVGGVVPAQDYDFLYGAGVKGVYGPGTPIPASAKDVLEQIKKAQAQ
>NC_011992.1|WP_015913373.1|1970416_1971445_+|methylmalonyl-Co-A-mutase-associated-GTPase-MeaB
MTPQQLQEGILHGAPAVRRRAMAKAITLLESTRADHRTQGDELLTALLPHTGRAFRLGISGVPGVGKSTFIEALGLHLIAQGLKVAVLAIDPSSTVSGGSILGDKTRMEHLSVHPDAYIRPSPSSGTLGGVAEKTREAMLVCEAAGYDVVIIETVGVGQSEIAVQGMTDMFCVLQLPNAGDDLQAIKKGVMELADLVVINKADIDPHAATRAQAQITSSLRLLSMHGNPEHAHHDESLWTPKVITLSALKGEGVDGFWAAVQEFRRLQTANGRLAARRERQSLAWMWERIDAGLKQAFRQHPQVRELLPRLQQDVAAGRVAASTAARNLLAAQSGQALQATI
>NC_011992.1|WP_015913374.1|1971470_1973003_+|acyl-CoA-carboxylase-subunit-beta
MQDILDQLEKKRELARLGGGQKRIDAQHKKGKLTARERIELLLDDGTFEEWDMFVEHRCTDFGMENTKIPGDGVVTGYGMINGRLVFVFSQDFTVFGGALSETHAEKICKVMDQAMKVGAPVIGLNDSGGARIQEGVASLGGYADVFQKNVLASGVIPQISMIMGPCAGGAVYSPAMTDFIFMVKDSSYMFVTGPEVVKTVTHEEVTAEELGGAITHTTKSGVADMAFENDVEALMMLRRLYNYLPLNNKEKAPVRPSNDPADRADLSLDTLVPDNPNKPYDMKELIVKTVDDGDFFELQPDYAKNILIGFARMEGQTVGIVANQPLVLAGCLDIKSSIKAARFVRFCDAFNIPVITFVDVPGFMPGTSQEYGGIIKHGAKLLYAYAECTVPKITVITRKAYGGAYDVMSSKHLRGDVNLAWPNAEIAVMGAKGAVEIIFREDKNDPAKLAAREAEYKARFANPFVAGARGFIDDVILPHETRKRICRSLAMLKNKQLDNPWRKHGNIPL
>NC_011992.1|WP_015913375.1|1973019_1973460_+|PH-domain-containing-protein
MTHTRPVFFSRVDAWILAIGPVTGLAAVGMALPPALRSGATAEVAVLGIVLASTLILPIWLLLDTHYTFTADTLRVHCGPFCWRIALAEVTEVSPSRSWVSSPALSLDRLRIRYGRGRSILLSPREKQRFVEQLRPQCPHVLVTGF
>NC_011992.1|WP_015913376.1|1973482_1975531_+|acetyl/propionyl/methylcrotonyl-CoA-carboxylase-subunit-alpha
MFTKILIANRGEIACRVIATAKKMGIATVAVYSDADKDARHVKLADEAVHIGAAPSRESYLLADKIIAACKQTGAQAVHPGYGFLSENEAFAKRVEEEGIVFIGPKHAAIAAMGDKIASKKLANQAGVNTIPGYNDPIAGPEAAVEIAKGIGYPVMIKASAGGGGKGLRVAFNDKEAFEGFASCQNEARNSFGDDRIFIEKFVQEPRHIEIQVLGDAHGNVIYLNERECSIQRRHQKVIEEAPSPFISDATRKAMGEQAVALAKAVGYQSAGTVEFVVGKDQDFYFLEMNTRLQVEHPVTECITGLDLVELMIRVAAGEKLAIRQEDVKRDGWAIECRINAEDPFRNFLPSTGRLVRFQAPEESMFQGDTTKKYGVRVDTGVFEGGEIPMYYDSMIAKLIVHGQDRNDAIEKMRAALNGFVIRGISSNIPFQAALLAHPKFVAGQFNTGFIAEHYSKGFAAEDVPHDDPLFLVALAAYMNRRYRARASGISGQLTGHEVQVGAQFTVVVLGAQGNNIHHEVTVTDYEPESRSSAVTIGNTTYRISSTAGLGDIRVQGQCNGKGFTAQVERGTAKNPLALRISHNGTQIDALVLSPLGARLHQLMPFKAPPDLSKFLLSPMPGLLVDVAVQPGQKVQAGEKLAVIEAMKMENILFAAQDGVVGKIVAGKGESLAVDQVILEFQ

You can click texts colored in the table to view more detailed information

Click the colored protein region to show detailed information

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NC_011992_1	1.2\|61597\|30\|NC_011992\|CRISPRCasFinder,CRT,PILER-CR	61597-61626	30	NZ_CP021369	Acidovorax carolinensis strain P4 plasmid pACP4.3, complete sequence	11190-11219	0	1.0
NC_011992_1	1.13\|62323\|30\|NC_011992\|CRISPRCasFinder,CRT,PILER-CR	62323-62352	30	CP000662	Rhodobacter sphaeroides ATCC 17025 plasmid pRSPA01, complete sequence	589589-589618	5	0.833
NC_011992_3	3.1\|1961838\|29\|NC_011992\|CRISPRCasFinder	1961838-1961866	29	NC_008010	Deinococcus geothermalis DSM 11300 plasmid pDGEO01, complete sequence	452784-452812	5	0.828
NC_011992_1	1.13\|62323\|30\|NC_011992\|CRISPRCasFinder,CRT,PILER-CR	62323-62352	30	NZ_CP040764	Paracoccus sp. 2251 plasmid unnamed3, complete sequence	65332-65361	7	0.767
NC_011992_1	1.13\|62323\|30\|NC_011992\|CRISPRCasFinder,CRT,PILER-CR	62323-62352	30	JX163858	Caulobacter phage phiCbK, complete genome	182483-182512	7	0.767
NC_011992_1	1.13\|62323\|30\|NC_011992\|CRISPRCasFinder,CRT,PILER-CR	62323-62352	30	NZ_CP050991	Chromobacterium violaceum strain FDAARGOS_635 plasmid unnamed, complete sequence	42259-42288	7	0.767
NC_011992_1	1.13\|62323\|30\|NC_011992\|CRISPRCasFinder,CRT,PILER-CR	62323-62352	30	NZ_MG651603	Chromobacterium violaceum strain ATCC 12472 plasmid pChV1, complete sequence	29283-29312	7	0.767
NC_011992_1	1.13\|62323\|30\|NC_011992\|CRISPRCasFinder,CRT,PILER-CR	62323-62352	30	KY555147	Caulobacter phage Ccr34, complete genome	25344-25373	7	0.767
NC_011992_1	1.13\|62323\|30\|NC_011992\|CRISPRCasFinder,CRT,PILER-CR	62323-62352	30	KY555146	Caulobacter phage Ccr32, complete genome	25345-25374	7	0.767
NC_011992_1	1.13\|62323\|30\|NC_011992\|CRISPRCasFinder,CRT,PILER-CR	62323-62352	30	NZ_CP024609	Massilia violaceinigra strain B2 plasmid unnamed, complete sequence	24172-24201	7	0.767
NC_011992_1	1.13\|62323\|30\|NC_011992\|CRISPRCasFinder,CRT,PILER-CR	62323-62352	30	NZ_AP022319	Burkholderia sp. THE68 plasmid BTHE68_p1, complete sequence	468266-468295	7	0.767
NC_011992_1	1.14\|62389\|30\|NC_011992\|CRISPRCasFinder,CRT,PILER-CR	62389-62418	30	NZ_CP011248	Agrobacterium tumefaciens strain Ach5 plasmid pAt, complete sequence	396330-396359	7	0.767
NC_011992_1	1.14\|62389\|30\|NC_011992\|CRISPRCasFinder,CRT,PILER-CR	62389-62418	30	NZ_CP032919	Agrobacterium tumefaciens strain 15955 plasmid pAt15955, complete sequence	667040-667069	7	0.767
NC_011992_1	1.14\|62389\|30\|NC_011992\|CRISPRCasFinder,CRT,PILER-CR	62389-62418	30	NZ_CP033029	Agrobacterium tumefaciens strain A6 plasmid pAtA6, complete sequence	667123-667152	7	0.767
NC_011992_3	3.1\|1961838\|29\|NC_011992\|CRISPRCasFinder	1961838-1961866	29	NC_015727	Cupriavidus necator N-1 plasmid pBB1, complete sequence	39323-39351	7	0.759
NC_011992_1	1.4\|61729\|30\|NC_011992\|CRISPRCasFinder,CRT,PILER-CR	61729-61758	30	NZ_CP038636	Cupriavidus oxalaticus strain X32 plasmid unnamed1, complete sequence	244959-244988	8	0.733
NC_011992_1	1.4\|61729\|30\|NC_011992\|CRISPRCasFinder,CRT,PILER-CR	61729-61758	30	NC_023714	Mycobacterium phage LinStu, complete genome	20334-20363	8	0.733
NC_011992_1	1.4\|61729\|30\|NC_011992\|CRISPRCasFinder,CRT,PILER-CR	61729-61758	30	MT889395	Mycobacterium phage Shifa, complete genome	18434-18463	8	0.733
NC_011992_1	1.4\|61729\|30\|NC_011992\|CRISPRCasFinder,CRT,PILER-CR	61729-61758	30	MK450422	Mycobacterium phage RoMag, complete genome	18500-18529	8	0.733
NC_011992_1	1.4\|61729\|30\|NC_011992\|CRISPRCasFinder,CRT,PILER-CR	61729-61758	30	MK359355	Mycobacterium phage Sprinklers, complete genome	18499-18528	8	0.733
NC_011992_1	1.4\|61729\|30\|NC_011992\|CRISPRCasFinder,CRT,PILER-CR	61729-61758	30	MK359349	Mycobacterium phage FoxtrotP1, complete genome	19909-19938	8	0.733
NC_011992_1	1.4\|61729\|30\|NC_011992\|CRISPRCasFinder,CRT,PILER-CR	61729-61758	30	MK359345	Mycobacterium phage QBert, complete genome	19318-19347	8	0.733
NC_011992_1	1.4\|61729\|30\|NC_011992\|CRISPRCasFinder,CRT,PILER-CR	61729-61758	30	NC_028869	Mycobacterium phage HyRo, complete genome	18988-19017	8	0.733
NC_011992_1	1.4\|61729\|30\|NC_011992\|CRISPRCasFinder,CRT,PILER-CR	61729-61758	30	JN204348	Mycobacterium phage Sebata, complete genome	20453-20482	8	0.733
NC_011992_1	1.5\|61795\|30\|NC_011992\|CRISPRCasFinder,CRT,PILER-CR	61795-61824	30	NZ_CP038636	Cupriavidus oxalaticus strain X32 plasmid unnamed1, complete sequence	244959-244988	8	0.733
NC_011992_1	1.5\|61795\|30\|NC_011992\|CRISPRCasFinder,CRT,PILER-CR	61795-61824	30	NC_023714	Mycobacterium phage LinStu, complete genome	20334-20363	8	0.733
NC_011992_1	1.5\|61795\|30\|NC_011992\|CRISPRCasFinder,CRT,PILER-CR	61795-61824	30	MT889395	Mycobacterium phage Shifa, complete genome	18434-18463	8	0.733
NC_011992_1	1.5\|61795\|30\|NC_011992\|CRISPRCasFinder,CRT,PILER-CR	61795-61824	30	MK450422	Mycobacterium phage RoMag, complete genome	18500-18529	8	0.733
NC_011992_1	1.5\|61795\|30\|NC_011992\|CRISPRCasFinder,CRT,PILER-CR	61795-61824	30	MK359355	Mycobacterium phage Sprinklers, complete genome	18499-18528	8	0.733
NC_011992_1	1.5\|61795\|30\|NC_011992\|CRISPRCasFinder,CRT,PILER-CR	61795-61824	30	MK359349	Mycobacterium phage FoxtrotP1, complete genome	19909-19938	8	0.733
NC_011992_1	1.5\|61795\|30\|NC_011992\|CRISPRCasFinder,CRT,PILER-CR	61795-61824	30	MK359345	Mycobacterium phage QBert, complete genome	19318-19347	8	0.733
NC_011992_1	1.5\|61795\|30\|NC_011992\|CRISPRCasFinder,CRT,PILER-CR	61795-61824	30	NC_028869	Mycobacterium phage HyRo, complete genome	18988-19017	8	0.733
NC_011992_1	1.5\|61795\|30\|NC_011992\|CRISPRCasFinder,CRT,PILER-CR	61795-61824	30	JN204348	Mycobacterium phage Sebata, complete genome	20453-20482	8	0.733
NC_011992_1	1.7\|61927\|30\|NC_011992\|CRISPRCasFinder,CRT,PILER-CR	61927-61956	30	MK240575	Thermobifida phage P318, complete genome	46282-46311	8	0.733
NC_011992_1	1.11\|62191\|30\|NC_011992\|CRISPRCasFinder,CRT,PILER-CR	62191-62220	30	NZ_CP027853	Plesiomonas shigelloides strain MS-17-188 plasmid pPS-MS-17-188-1, complete sequence	185552-185581	8	0.733
NC_011992_1	1.12\|62257\|30\|NC_011992\|CRISPRCasFinder,CRT,PILER-CR	62257-62286	30	NZ_CP020716	Cnuibacter physcomitrellae strain XA(T) plasmid unnamed1, complete sequence	56866-56895	8	0.733
NC_011992_1	1.13\|62323\|30\|NC_011992\|CRISPRCasFinder,CRT,PILER-CR	62323-62352	30	NZ_CP015742	Shinella sp. HZN7 plasmid pShin-06, complete sequence	49603-49632	8	0.733
NC_011992_1	1.14\|62389\|30\|NC_011992\|CRISPRCasFinder,CRT,PILER-CR	62389-62418	30	NZ_LR134403	Listeria monocytogenes strain NCTC7974 plasmid 6, complete sequence	196023-196052	8	0.733
NC_011992_1	1.3\|61663\|30\|NC_011992\|CRISPRCasFinder,CRT,PILER-CR	61663-61692	30	NZ_CP026974	Achromobacter insolitus strain FDAARGOS_88 plasmid unnamed1, complete sequence	325561-325590	9	0.7
NC_011992_1	1.6\|61861\|30\|NC_011992\|CRISPRCasFinder,CRT,PILER-CR	61861-61890	30	NC_048704	Pectobacterium phage Nepra, complete genome	70659-70688	9	0.7
NC_011992_1	1.6\|61861\|30\|NC_011992\|CRISPRCasFinder,CRT,PILER-CR	61861-61890	30	NC_048659	Pectobacterium phage phiA41, complete genome	56363-56392	9	0.7
NC_011992_1	1.6\|61861\|30\|NC_011992\|CRISPRCasFinder,CRT,PILER-CR	61861-61890	30	KY083726	Pectobacterium phage A38, complete genome	56363-56392	9	0.7
NC_011992_1	1.13\|62323\|30\|NC_011992\|CRISPRCasFinder,CRT,PILER-CR	62323-62352	30	MK977714	Corynebacterium phage Bran, complete genome	8978-9007	9	0.7
NC_011992_1	1.13\|62323\|30\|NC_011992\|CRISPRCasFinder,CRT,PILER-CR	62323-62352	30	NC_048780	Corynebacterium phage StAB, complete genome	8966-8995	9	0.7
NC_011992_1	1.13\|62323\|30\|NC_011992\|CRISPRCasFinder,CRT,PILER-CR	62323-62352	30	MK977706	Corynebacterium phage Dina, complete genome	8962-8991	9	0.7
NC_011992_1	1.13\|62323\|30\|NC_011992\|CRISPRCasFinder,CRT,PILER-CR	62323-62352	30	MH926061	Corynebacterium phage Troy, complete genome	8960-8989	9	0.7
NC_011992_1	1.13\|62323\|30\|NC_011992\|CRISPRCasFinder,CRT,PILER-CR	62323-62352	30	NC_048789	Corynebacterium phage Stiles, complete genome	8960-8989	9	0.7
NC_011992_1	1.13\|62323\|30\|NC_011992\|CRISPRCasFinder,CRT,PILER-CR	62323-62352	30	NC_048791	Corynebacterium phage Adelaide, complete genome	8973-9002	9	0.7
NC_011992_1	1.13\|62323\|30\|NC_011992\|CRISPRCasFinder,CRT,PILER-CR	62323-62352	30	NC_048069	Corynebacterium phage SamW, complete genome	8960-8989	9	0.7
NC_011992_1	1.13\|62323\|30\|NC_011992\|CRISPRCasFinder,CRT,PILER-CR	62323-62352	30	NC_048790	Corynebacterium phage Lederberg, complete genome	8960-8989	9	0.7
NC_011992_1	1.14\|62389\|30\|NC_011992\|CRISPRCasFinder,CRT,PILER-CR	62389-62418	30	MN734438	Sphingomonas phage Lucius, complete genome	38238-38267	9	0.7

1. spacer 1.2|61597|30|NC_011992|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP021369 (Acidovorax carolinensis strain P4 plasmid pACP4.3, complete sequence) position: , mismatch: 0, identity: 1.0

cggcagggtttgggggaggcgattaaattt	CRISPR spacer
cggcagggtttgggggaggcgattaaattt	Protospacer
******************************

2. spacer 1.13|62323|30|NC_011992|CRISPRCasFinder,CRT,PILER-CR matches to CP000662 (Rhodobacter sphaeroides ATCC 17025 plasmid pRSPA01, complete sequence) position: , mismatch: 5, identity: 0.833

ggctacgcccggcgcgaagaggccatcgct	CRISPR spacer
gccgatgccctgcgcgaagcggccatcgct	Protospacer
* * *.**** ******** **********

3. spacer 3.1|1961838|29|NC_011992|CRISPRCasFinder matches to NC_008010 (Deinococcus geothermalis DSM 11300 plasmid pDGEO01, complete sequence) position: , mismatch: 5, identity: 0.828

accgactggggcgtgcaggtgcaggaatc----	CRISPR spacer
accgactggggcgtggaggt----gaatctccg	Protospacer
*************** ****    *****

4. spacer 1.13|62323|30|NC_011992|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP040764 (Paracoccus sp. 2251 plasmid unnamed3, complete sequence) position: , mismatch: 7, identity: 0.767

ggctacgcccggcgcgaagaggccatcgct	CRISPR spacer
gcggacgcccggcgcgaaacggccatcgac	Protospacer
*   **************. ******** .

5. spacer 1.13|62323|30|NC_011992|CRISPRCasFinder,CRT,PILER-CR matches to JX163858 (Caulobacter phage phiCbK, complete genome) position: , mismatch: 7, identity: 0.767

ggctacgcccggcgcgaagaggccatcgct	CRISPR spacer
gcgatcgcccggcgcgacgaggccctcgcg	Protospacer
*    ************ ****** ****

6. spacer 1.13|62323|30|NC_011992|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP050991 (Chromobacterium violaceum strain FDAARGOS_635 plasmid unnamed, complete sequence) position: , mismatch: 7, identity: 0.767

ggctacgcccggcgcgaagaggccatcgct	CRISPR spacer
ttcgccgccctgcgcgaggaggccatcgcc	Protospacer
  *  ***** ******.***********.

7. spacer 1.13|62323|30|NC_011992|CRISPRCasFinder,CRT,PILER-CR matches to NZ_MG651603 (Chromobacterium violaceum strain ATCC 12472 plasmid pChV1, complete sequence) position: , mismatch: 7, identity: 0.767

ggctacgcccggcgcgaagaggccatcgct	CRISPR spacer
ttcgccgccctgcgcgaggaggccatcgcc	Protospacer
  *  ***** ******.***********.

8. spacer 1.13|62323|30|NC_011992|CRISPRCasFinder,CRT,PILER-CR matches to KY555147 (Caulobacter phage Ccr34, complete genome) position: , mismatch: 7, identity: 0.767

ggctacgcccggcgcgaagaggccatcgct	CRISPR spacer
gcgatcgcccggcgcgacgaggccctcgcg	Protospacer
*    ************ ****** ****

9. spacer 1.13|62323|30|NC_011992|CRISPRCasFinder,CRT,PILER-CR matches to KY555146 (Caulobacter phage Ccr32, complete genome) position: , mismatch: 7, identity: 0.767

ggctacgcccggcgcgaagaggccatcgct	CRISPR spacer
gcgatcgcccggcgcgacgaggccctcgcg	Protospacer
*    ************ ****** ****

10. spacer 1.13|62323|30|NC_011992|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP024609 (Massilia violaceinigra strain B2 plasmid unnamed, complete sequence) position: , mismatch: 7, identity: 0.767

ggctacgcccggcgcgaagaggccatcgct	CRISPR spacer
tgtttcgcctggcgcgaacaggccatcgga	Protospacer
 *.* ****.******** *********

11. spacer 1.13|62323|30|NC_011992|CRISPRCasFinder,CRT,PILER-CR matches to NZ_AP022319 (Burkholderia sp. THE68 plasmid BTHE68_p1, complete sequence) position: , mismatch: 7, identity: 0.767

ggctacgcccggcgcgaagaggccatcgct	CRISPR spacer
gtcgccgcccagcgcgaagaagccatcgtc	Protospacer
* *  *****.*********.*******..

12. spacer 1.14|62389|30|NC_011992|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP011248 (Agrobacterium tumefaciens strain Ach5 plasmid pAt, complete sequence) position: , mismatch: 7, identity: 0.767

ctggacggagggacaacagcatgagcgaga	CRISPR spacer
atgcacggagggacatcagcatgacagcca	Protospacer
 ** *********** ********  *  *

13. spacer 1.14|62389|30|NC_011992|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP032919 (Agrobacterium tumefaciens strain 15955 plasmid pAt15955, complete sequence) position: , mismatch: 7, identity: 0.767

ctggacggagggacaacagcatgagcgaga	CRISPR spacer
atgcacggagggacatcagcatgacagcca	Protospacer
 ** *********** ********  *  *

14. spacer 1.14|62389|30|NC_011992|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP033029 (Agrobacterium tumefaciens strain A6 plasmid pAtA6, complete sequence) position: , mismatch: 7, identity: 0.767

ctggacggagggacaacagcatgagcgaga	CRISPR spacer
atgcacggagggacatcagcatgacagcca	Protospacer
 ** *********** ********  *  *

15. spacer 3.1|1961838|29|NC_011992|CRISPRCasFinder matches to NC_015727 (Cupriavidus necator N-1 plasmid pBB1, complete sequence) position: , mismatch: 7, identity: 0.759

accgactggggcgtgcaggtgcaggaatc	CRISPR spacer
gccgactggggcgtgcaggcgctcgagcg	Protospacer
.******************.**  **..

16. spacer 1.4|61729|30|NC_011992|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP038636 (Cupriavidus oxalaticus strain X32 plasmid unnamed1, complete sequence) position: , mismatch: 8, identity: 0.733

gaaagcaggtccggcaagctacgcgcgaca	CRISPR spacer
ggggtcaagtccggcaagctgcgcgcgatc	Protospacer
*... **.************.*******.

17. spacer 1.4|61729|30|NC_011992|CRISPRCasFinder,CRT,PILER-CR matches to NC_023714 (Mycobacterium phage LinStu, complete genome) position: , mismatch: 8, identity: 0.733

gaaagcaggtccggcaagctacgcgcgaca	CRISPR spacer
cgctcccggtccgaccagctacgcgcgaca	Protospacer
 .   * ******.* **************

18. spacer 1.4|61729|30|NC_011992|CRISPRCasFinder,CRT,PILER-CR matches to MT889395 (Mycobacterium phage Shifa, complete genome) position: , mismatch: 8, identity: 0.733

gaaagcaggtccggcaagctacgcgcgaca	CRISPR spacer
cgctcccggtccgaccagctacgcgcgaca	Protospacer
 .   * ******.* **************

19. spacer 1.4|61729|30|NC_011992|CRISPRCasFinder,CRT,PILER-CR matches to MK450422 (Mycobacterium phage RoMag, complete genome) position: , mismatch: 8, identity: 0.733

gaaagcaggtccggcaagctacgcgcgaca	CRISPR spacer
cgctcccggtccgaccagctacgcgcgaca	Protospacer
 .   * ******.* **************

20. spacer 1.4|61729|30|NC_011992|CRISPRCasFinder,CRT,PILER-CR matches to MK359355 (Mycobacterium phage Sprinklers, complete genome) position: , mismatch: 8, identity: 0.733

gaaagcaggtccggcaagctacgcgcgaca	CRISPR spacer
cgctcccggtccgaccagctacgcgcgaca	Protospacer
 .   * ******.* **************

21. spacer 1.4|61729|30|NC_011992|CRISPRCasFinder,CRT,PILER-CR matches to MK359349 (Mycobacterium phage FoxtrotP1, complete genome) position: , mismatch: 8, identity: 0.733

gaaagcaggtccggcaagctacgcgcgaca	CRISPR spacer
cgctcccggtccgaccagctacgcgcgaca	Protospacer
 .   * ******.* **************

22. spacer 1.4|61729|30|NC_011992|CRISPRCasFinder,CRT,PILER-CR matches to MK359345 (Mycobacterium phage QBert, complete genome) position: , mismatch: 8, identity: 0.733

gaaagcaggtccggcaagctacgcgcgaca	CRISPR spacer
cgctcccggtccgaccagctacgcgcgaca	Protospacer
 .   * ******.* **************

23. spacer 1.4|61729|30|NC_011992|CRISPRCasFinder,CRT,PILER-CR matches to NC_028869 (Mycobacterium phage HyRo, complete genome) position: , mismatch: 8, identity: 0.733

gaaagcaggtccggcaagctacgcgcgaca	CRISPR spacer
cgctcccggtccgaccagctacgcgcgaca	Protospacer
 .   * ******.* **************

24. spacer 1.4|61729|30|NC_011992|CRISPRCasFinder,CRT,PILER-CR matches to JN204348 (Mycobacterium phage Sebata, complete genome) position: , mismatch: 8, identity: 0.733

gaaagcaggtccggcaagctacgcgcgaca	CRISPR spacer
cgctcccggtccgaccagctacgcgcgaca	Protospacer
 .   * ******.* **************

25. spacer 1.5|61795|30|NC_011992|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP038636 (Cupriavidus oxalaticus strain X32 plasmid unnamed1, complete sequence) position: , mismatch: 8, identity: 0.733

gaaagcaggtccggcaagctacgcgcgaca	CRISPR spacer
ggggtcaagtccggcaagctgcgcgcgatc	Protospacer
*... **.************.*******.

26. spacer 1.5|61795|30|NC_011992|CRISPRCasFinder,CRT,PILER-CR matches to NC_023714 (Mycobacterium phage LinStu, complete genome) position: , mismatch: 8, identity: 0.733

gaaagcaggtccggcaagctacgcgcgaca	CRISPR spacer
cgctcccggtccgaccagctacgcgcgaca	Protospacer
 .   * ******.* **************

27. spacer 1.5|61795|30|NC_011992|CRISPRCasFinder,CRT,PILER-CR matches to MT889395 (Mycobacterium phage Shifa, complete genome) position: , mismatch: 8, identity: 0.733

gaaagcaggtccggcaagctacgcgcgaca	CRISPR spacer
cgctcccggtccgaccagctacgcgcgaca	Protospacer
 .   * ******.* **************

28. spacer 1.5|61795|30|NC_011992|CRISPRCasFinder,CRT,PILER-CR matches to MK450422 (Mycobacterium phage RoMag, complete genome) position: , mismatch: 8, identity: 0.733

gaaagcaggtccggcaagctacgcgcgaca	CRISPR spacer
cgctcccggtccgaccagctacgcgcgaca	Protospacer
 .   * ******.* **************

29. spacer 1.5|61795|30|NC_011992|CRISPRCasFinder,CRT,PILER-CR matches to MK359355 (Mycobacterium phage Sprinklers, complete genome) position: , mismatch: 8, identity: 0.733

gaaagcaggtccggcaagctacgcgcgaca	CRISPR spacer
cgctcccggtccgaccagctacgcgcgaca	Protospacer
 .   * ******.* **************

30. spacer 1.5|61795|30|NC_011992|CRISPRCasFinder,CRT,PILER-CR matches to MK359349 (Mycobacterium phage FoxtrotP1, complete genome) position: , mismatch: 8, identity: 0.733

gaaagcaggtccggcaagctacgcgcgaca	CRISPR spacer
cgctcccggtccgaccagctacgcgcgaca	Protospacer
 .   * ******.* **************

31. spacer 1.5|61795|30|NC_011992|CRISPRCasFinder,CRT,PILER-CR matches to MK359345 (Mycobacterium phage QBert, complete genome) position: , mismatch: 8, identity: 0.733

gaaagcaggtccggcaagctacgcgcgaca	CRISPR spacer
cgctcccggtccgaccagctacgcgcgaca	Protospacer
 .   * ******.* **************

32. spacer 1.5|61795|30|NC_011992|CRISPRCasFinder,CRT,PILER-CR matches to NC_028869 (Mycobacterium phage HyRo, complete genome) position: , mismatch: 8, identity: 0.733

gaaagcaggtccggcaagctacgcgcgaca	CRISPR spacer
cgctcccggtccgaccagctacgcgcgaca	Protospacer
 .   * ******.* **************

33. spacer 1.5|61795|30|NC_011992|CRISPRCasFinder,CRT,PILER-CR matches to JN204348 (Mycobacterium phage Sebata, complete genome) position: , mismatch: 8, identity: 0.733

gaaagcaggtccggcaagctacgcgcgaca	CRISPR spacer
cgctcccggtccgaccagctacgcgcgaca	Protospacer
 .   * ******.* **************

34. spacer 1.7|61927|30|NC_011992|CRISPRCasFinder,CRT,PILER-CR matches to MK240575 (Thermobifida phage P318, complete genome) position: , mismatch: 8, identity: 0.733

cattccccccgtggctcgtaatttcgcatt	CRISPR spacer
ctacttccccgtggctagtaacttcgcatg	Protospacer
*  ...********** ****.*******

35. spacer 1.11|62191|30|NC_011992|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP027853 (Plesiomonas shigelloides strain MS-17-188 plasmid pPS-MS-17-188-1, complete sequence) position: , mismatch: 8, identity: 0.733

ggatcgccgtgggtaatgcgaacgacgtta	CRISPR spacer
cgatcaccgtgggtaatgcgaaattcagtg	Protospacer
 ****.****************   *. *.

36. spacer 1.12|62257|30|NC_011992|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP020716 (Cnuibacter physcomitrellae strain XA(T) plasmid unnamed1, complete sequence) position: , mismatch: 8, identity: 0.733

aacacgttcccagcggccttttgggcgtcc	CRISPR spacer
tcgatcggcccagcggccttttgggcgccc	Protospacer
   *.   *******************.**

37. spacer 1.13|62323|30|NC_011992|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP015742 (Shinella sp. HZN7 plasmid pShin-06, complete sequence) position: , mismatch: 8, identity: 0.733

ggctacgcccggcgcgaagaggccatcgct	CRISPR spacer
gaacatgcccggcgcgaagaggtcatccaa	Protospacer
*. .*.****************.****

38. spacer 1.14|62389|30|NC_011992|CRISPRCasFinder,CRT,PILER-CR matches to NZ_LR134403 (Listeria monocytogenes strain NCTC7974 plasmid 6, complete sequence) position: , mismatch: 8, identity: 0.733

ctggacggagggacaacagcatgagcgaga	CRISPR spacer
tgaattggagggacgacagcatgagagaga	Protospacer
. .. .********.********** ****

39. spacer 1.3|61663|30|NC_011992|CRISPRCasFinder,CRT,PILER-CR matches to NZ_CP026974 (Achromobacter insolitus strain FDAARGOS_88 plasmid unnamed1, complete sequence) position: , mismatch: 9, identity: 0.7

cagctatgcagcgcagggcatatgctgcat	CRISPR spacer
tcatttcgctgcgcagggcatatgctgccg	Protospacer
. ..* .** ******************

40. spacer 1.6|61861|30|NC_011992|CRISPRCasFinder,CRT,PILER-CR matches to NC_048704 (Pectobacterium phage Nepra, complete genome) position: , mismatch: 9, identity: 0.7

atcagcctgagcctttgcagaggcttcctc	CRISPR spacer
cgacatttgagcttttgcataggcttcctc	Protospacer
    ...*****.****** **********

41. spacer 1.6|61861|30|NC_011992|CRISPRCasFinder,CRT,PILER-CR matches to NC_048659 (Pectobacterium phage phiA41, complete genome) position: , mismatch: 9, identity: 0.7

atcagcctgagcctttgcagaggcttcctc	CRISPR spacer
cgacatttgagcttttgcataggcttcctc	Protospacer
    ...*****.****** **********

42. spacer 1.6|61861|30|NC_011992|CRISPRCasFinder,CRT,PILER-CR matches to KY083726 (Pectobacterium phage A38, complete genome) position: , mismatch: 9, identity: 0.7

atcagcctgagcctttgcagaggcttcctc	CRISPR spacer
cgacatttgagcttttgcataggcttcctc	Protospacer
    ...*****.****** **********

43. spacer 1.13|62323|30|NC_011992|CRISPRCasFinder,CRT,PILER-CR matches to MK977714 (Corynebacterium phage Bran, complete genome) position: , mismatch: 9, identity: 0.7

ggctacgcccggcgcgaagaggccatcgct	CRISPR spacer
attgtcgcccagcgcgaagaggccaccggc	Protospacer
. .  *****.**************.** .

44. spacer 1.13|62323|30|NC_011992|CRISPRCasFinder,CRT,PILER-CR matches to NC_048780 (Corynebacterium phage StAB, complete genome) position: , mismatch: 9, identity: 0.7

ggctacgcccggcgcgaagaggccatcgct	CRISPR spacer
attgtcgcccagcgcgaagaggccaccggc	Protospacer
. .  *****.**************.** .

45. spacer 1.13|62323|30|NC_011992|CRISPRCasFinder,CRT,PILER-CR matches to MK977706 (Corynebacterium phage Dina, complete genome) position: , mismatch: 9, identity: 0.7

ggctacgcccggcgcgaagaggccatcgct	CRISPR spacer
attgtcgcccagcgcgaagaggccaccggc	Protospacer
. .  *****.**************.** .

46. spacer 1.13|62323|30|NC_011992|CRISPRCasFinder,CRT,PILER-CR matches to MH926061 (Corynebacterium phage Troy, complete genome) position: , mismatch: 9, identity: 0.7

ggctacgcccggcgcgaagaggccatcgct	CRISPR spacer
attgtcgcccagcgcgaagaggccaccggc	Protospacer
. .  *****.**************.** .

47. spacer 1.13|62323|30|NC_011992|CRISPRCasFinder,CRT,PILER-CR matches to NC_048789 (Corynebacterium phage Stiles, complete genome) position: , mismatch: 9, identity: 0.7

ggctacgcccggcgcgaagaggccatcgct	CRISPR spacer
attgtcgcccagcgcgaagaggccaccggc	Protospacer
. .  *****.**************.** .

48. spacer 1.13|62323|30|NC_011992|CRISPRCasFinder,CRT,PILER-CR matches to NC_048791 (Corynebacterium phage Adelaide, complete genome) position: , mismatch: 9, identity: 0.7

ggctacgcccggcgcgaagaggccatcgct	CRISPR spacer
attgtcgcccagcgcgaagaggccaccggc	Protospacer
. .  *****.**************.** .

49. spacer 1.13|62323|30|NC_011992|CRISPRCasFinder,CRT,PILER-CR matches to NC_048069 (Corynebacterium phage SamW, complete genome) position: , mismatch: 9, identity: 0.7

ggctacgcccggcgcgaagaggccatcgct	CRISPR spacer
attgtcgcccagcgcgaagaggccaccggc	Protospacer
. .  *****.**************.** .

50. spacer 1.13|62323|30|NC_011992|CRISPRCasFinder,CRT,PILER-CR matches to NC_048790 (Corynebacterium phage Lederberg, complete genome) position: , mismatch: 9, identity: 0.7

ggctacgcccggcgcgaagaggccatcgct	CRISPR spacer
attgtcgcccagcgcgaagaggccaccggc	Protospacer
. .  *****.**************.** .

51. spacer 1.14|62389|30|NC_011992|CRISPRCasFinder,CRT,PILER-CR matches to MN734438 (Sphingomonas phage Lucius, complete genome) position: , mismatch: 9, identity: 0.7

ctggacggagggacaacagcatgagcgaga	CRISPR spacer
tcaaccggaaggacaacagcatgaccgaag	Protospacer
.... ****.************** ***..

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

363627 : 374620

Acinetobacter_phage(42.86%)

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_012655420.1\|363627_365364_-	MCP four helix bundle domain-containing protein	A0A2H4J162	uncultured_Caudovirales_phage	1.0e-13	31.2
WP_011803828.1\|365485_366088_-	chalcone isomerase family protein	NA	NA	NA	NA
WP_012655421.1\|366444_367944_+	anthranilate synthase component I	S4VT78	Pandoravirus	1.1e-40	29.9
WP_011803830.1\|367940_368285_+	chorismate mutase	NA	NA	NA	NA
WP_012655422.1\|368281_368854_+	aminodeoxychorismate/anthranilate synthase component II	A0A0P0IKJ1	Acinetobacter_phage	2.2e-66	62.1
WP_011803832.1\|368951_369986_+	anthranilate phosphoribosyltransferase	A0A0N7IRD9	Acinetobacter_phage	4.3e-81	46.5
WP_012655423.1\|369996_370170_+	hypothetical protein	NA	NA	NA	NA
WP_012655424.1\|370240_371041_+	indole-3-glycerol phosphate synthase TrpC	A0A0P0IR83	Acinetobacter_phage	1.1e-63	52.1
WP_012655425.1\|371179_373852_+	diguanylate cyclase	A0A127AWB9	Bacillus_phage	8.7e-17	34.3
WP_012655426.1\|373906_374620_+	uracil-DNA glycosylase	A0A1L5JKJ8	Bubaline_alphaherpesvirus	1.5e-45	47.6

DBSCAN-SWA_2

572107 : 581529

Escherichia_phage(33.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_012655576.1\|572107_572998_+	dTDP-4-dehydrorhamnose reductase	A0A291LA50	Escherichia_phage	2.1e-20	31.8
WP_012655577.1\|573018_573909_+	glucose-1-phosphate thymidylyltransferase RfbA	I7I009	Enterobacteria_phage	4.4e-98	58.5
WP_012655578.1\|573908_574454_+	dTDP-4-dehydrorhamnose 3,5-epimerase	A0A291LA62	Escherichia_phage	4.2e-51	56.9
WP_012655579.1\|574467_575601_+	glycosyltransferase	NA	NA	NA	NA
WP_012655580.1\|575573_576719_-	glycosyltransferase family 4 protein	J7Q7I8	Aeropyrum_coil-shaped_virus	7.3e-05	31.6
WP_012655581.1\|576715_577543_-	D-hexose-6-phosphate mutarotase	NA	NA	NA	NA
WP_012655582.1\|577555_578422_-	GDP-mannose 4,6-dehydratase	NA	NA	NA	NA
WP_012655583.1\|578418_579459_-	GDP-mannose 4,6-dehydratase	M1I1J0	Paramecium_bursaria_Chlorella_virus	5.3e-103	55.0
WP_012655584.1\|579678_581529_-	glycosyltransferase	A9YVR0	Ostreococcus_tauri_virus	4.8e-06	28.2

DBSCAN-SWA_3

699169 : 708138

uncultured_virus(33.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_012655674.1\|699169_700645_-	glucose-6-phosphate dehydrogenase	M4QQY0	Cyanophage	1.7e-62	33.7
WP_012655675.1\|700840_701791_+	transaldolase	A0A1D8KSY7	Synechococcus_phage	2.4e-09	33.3
WP_012655676.1\|701787_703404_+	glucose-6-phosphate isomerase	NA	NA	NA	NA
WP_012655677.1\|703434_704601_-	GGDEF domain-containing protein	A0A127AWB9	Bacillus_phage	8.8e-14	33.3
WP_012655678.1\|704871_706512_-	chaperonin GroEL	A0A219YK78	uncultured_virus	7.9e-170	60.9
WP_011804151.1\|706602_706893_-	co-chaperone GroES	A0A221S4A8	uncultured_virus	2.9e-19	46.8
WP_012655679.1\|707103_708138_-	bifunctional nicotinamide-nucleotide adenylyltransferase/Nudix hydroxylase	A0A1B0V161	Roseobacter_phage	5.3e-63	41.5

DBSCAN-SWA_4

3360410 : 3450024

Acidithiobacillus_phage(43.59%)

capsid,tRNA,head,integrase,terminase,portal,tail,transposase

attL 3356389:3356405|attR 3384552:3384568

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
3356389:3356405	attL	NA	NA	NA	NA
WP_015914401.1\|3360410_3361583_+\|tRNA	tRNA guanosine(34) transglycosylase Tgt	A0A1B1IVQ4	uncultured_Mediterranean_phage	4.9e-81	43.9
WP_015914402.1\|3361662_3362412_+	DUF72 domain-containing protein	NA	NA	NA	NA
WP_015914403.1\|3362408_3363569_-	hypothetical protein	NA	NA	NA	NA
WP_015914404.1\|3363647_3364448_-	DUF2145 domain-containing protein	NA	NA	NA	NA
WP_041839085.1\|3364450_3364909_-	hypothetical protein	NA	NA	NA	NA
WP_015914406.1\|3364932_3365415_-	hypothetical protein	NA	NA	NA	NA
WP_015914407.1\|3365543_3366053_-	Lrp/AsnC family transcriptional regulator	NA	NA	NA	NA
WP_015914408.1\|3366193_3367210_+	1-aminocyclopropane-1-carboxylate deaminase	NA	NA	NA	NA
WP_015914409.1\|3367249_3369205_-	MFS transporter	NA	NA	NA	NA
WP_011806966.1\|3369339_3370083_+	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_015914412.1\|3371365_3371782_+	YXWGXW repeat-containing protein	NA	NA	NA	NA
WP_011806970.1\|3371948_3372935_+	tripartite tricarboxylate transporter substrate binding protein	NA	NA	NA	NA
WP_015914413.1\|3372967_3374446_+	NAD(P)/FAD-dependent oxidoreductase	NA	NA	NA	NA
WP_015914414.1\|3374442_3375552_+	peroxidase-related enzyme	NA	NA	NA	NA
WP_015914415.1\|3375928_3377239_+	D-amino acid dehydrogenase	NA	NA	NA	NA
WP_011806974.1\|3377310_3378576_-	FIST C-terminal domain-containing protein	NA	NA	NA	NA
WP_015914416.1\|3378616_3379612_-	hypothetical protein	NA	NA	NA	NA
WP_011806976.1\|3379832_3380252_+	HU family DNA-binding protein	NA	NA	NA	NA
WP_041838898.1\|3380339_3381092_-	tyrosine-protein phosphatase	NA	NA	NA	NA
WP_187148584.1\|3381518_3382796_+\|integrase	integrase arm-type DNA-binding domain-containing protein	B7SYF8	Stenotrophomonas_phage	2.2e-106	49.5
WP_011805843.1\|3383301_3384528_-\|transposase	IS256 family transposase	A0A218MNI5	uncultured_virus	3.6e-50	48.7
WP_148215382.1\|3385187_3385403_-	AlpA family phage regulatory protein	NA	NA	NA	NA
3384552:3384568	attR	NA	NA	NA	NA
WP_015914420.1\|3386086_3386872_+	TIGR04255 family protein	NA	NA	NA	NA
WP_015914421.1\|3386874_3387516_+	hypothetical protein	NA	NA	NA	NA
WP_148215416.1\|3387593_3388373_+	hypothetical protein	NA	NA	NA	NA
WP_015914423.1\|3388523_3388994_+	hypothetical protein	NA	NA	NA	NA
WP_015914424.1\|3389130_3390696_+	recombinase family protein	E5DV73	Deep-sea_thermophilic_phage	1.3e-09	26.9
WP_015914425.1\|3390692_3391604_+	ParB/RepB/Spo0J family partition protein	NA	NA	NA	NA
WP_015914426.1\|3391600_3392479_+	ParB N-terminal domain-containing protein	NA	NA	NA	NA
WP_049760633.1\|3392523_3393858_+	hypothetical protein	NA	NA	NA	NA
WP_015914428.1\|3394292_3395210_+	WYL domain-containing protein	NA	NA	NA	NA
WP_015914429.1\|3395275_3396025_+	type III restriction protein res subunit	NA	NA	NA	NA
WP_085945350.1\|3396011_3397162_-\|transposase	IS3 family transposase	U5P429	Shigella_phage	1.3e-97	62.0
WP_041838900.1\|3397229_3398387_+	hypothetical protein	NA	NA	NA	NA
WP_148215383.1\|3398383_3398755_+	hypothetical protein	NA	NA	NA	NA
WP_187148585.1\|3398759_3401393_+	hypothetical protein	NA	NA	NA	NA
WP_187148586.1\|3401543_3403244_+	AAA family ATPase	NA	NA	NA	NA
WP_148215384.1\|3403240_3404503_+	hypothetical protein	NA	NA	NA	NA
WP_015914434.1\|3404509_3405694_-	site-specific DNA-methyltransferase	K4HZA5	Acidithiobacillus_phage	2.0e-05	44.6
WP_015914435.1\|3405913_3406894_+	HNH endonuclease	A0A2P0QEG9	Haloarcula_hispanica_pleomorphic_virus	1.0e-07	28.3
WP_015914436.1\|3406955_3407426_-	lysozyme	K4I410	Acidithiobacillus_phage	8.5e-69	79.7
WP_015914437.1\|3407422_3407899_-	hypothetical protein	K4ICR8	Acidithiobacillus_phage	3.6e-75	89.1
WP_015914438.1\|3407895_3408204_-	hypothetical protein	K4I011	Acidithiobacillus_phage	3.8e-25	80.0
WP_015914439.1\|3408283_3408505_-	hypothetical protein	NA	NA	NA	NA
WP_015914440.1\|3408497_3410453_-	hypothetical protein	A0A0M4UKC5	Ralstonia_phage	5.7e-58	36.8
WP_015914441.1\|3410470_3410866_-	hypothetical protein	Q6VSZ7	Vibrio_phage	3.9e-06	35.0
WP_015914442.1\|3410862_3411858_-	hypothetical protein	NA	NA	NA	NA
WP_015914443.1\|3411861_3413130_-	hypothetical protein	NA	NA	NA	NA
WP_015914444.1\|3413148_3416757_-	hypothetical protein	A0A0M4U447	Ralstonia_phage	5.9e-242	41.2
WP_015914445.1\|3416756_3417167_-	hypothetical protein	A0A0M4UTA7	Ralstonia_phage	1.8e-30	49.3
WP_015914446.1\|3417203_3421160_-\|tail	phage tail tape measure protein	A0A0P0ZCJ4	Stx2-converting_phage	7.3e-36	31.8
WP_015914447.1\|3421161_3421806_-	hypothetical protein	NA	NA	NA	NA
WP_041838904.1\|3421780_3421990_-	hypothetical protein	NA	NA	NA	NA
WP_015914448.1\|3421986_3422385_-	hypothetical protein	NA	NA	NA	NA
WP_015914449.1\|3422396_3423149_-	hypothetical protein	A0A2D2W2E0	Stenotrophomonas_phage	3.0e-47	45.4
WP_015914450.1\|3423145_3423364_-	hypothetical protein	NA	NA	NA	NA
WP_015914451.1\|3423369_3423816_-	hypothetical protein	A0A2I5ARB4	Synechococcus_phage	7.2e-09	32.6
WP_015914452.1\|3423819_3424122_-	hypothetical protein	NA	NA	NA	NA
WP_015914453.1\|3424121_3425126_-\|capsid	major capsid protein	Q9JMM2	Wolbachia_phage	3.2e-121	65.6
WP_015914454.1\|3425128_3425506_-\|head	head decoration protein	A0A1B2LRT0	Wolbachia_phage	2.7e-17	52.8
WP_015914455.1\|3425507_3426833_-	S49 family peptidase	K4HZZ6	Acidithiobacillus_phage	1.7e-66	50.7
WP_015914456.1\|3426878_3428378_-\|portal	phage portal protein	Q9JMM5	Wolbachia_phage	5.7e-151	56.8
WP_015914457.1\|3428377_3428584_-	hypothetical protein	A0A2H4JCJ9	uncultured_Caudovirales_phage	1.4e-23	83.8
WP_015914458.1\|3428613_3430569_-\|terminase	phage terminase large subunit family protein	A0A2H4JIC6	uncultured_Caudovirales_phage	0.0e+00	88.5
WP_015914459.1\|3430571_3431138_-	hypothetical protein	A0A2H4JCL4	uncultured_Caudovirales_phage	4.8e-50	60.1
WP_015914460.1\|3431248_3431455_+	hypothetical protein	NA	NA	NA	NA
WP_015914461.1\|3431550_3432132_+	DUF3489 domain-containing protein	A0A2H4JE21	uncultured_Caudovirales_phage	1.1e-28	85.3
WP_187148587.1\|3432610_3433078_+	hypothetical protein	NA	NA	NA	NA
WP_015914462.1\|3433110_3433353_+	hypothetical protein	NA	NA	NA	NA
WP_015914463.1\|3433316_3434594_-	site-specific DNA-methyltransferase	A0A2H4JGF1	uncultured_Caudovirales_phage	2.2e-220	88.3
WP_015914464.1\|3434590_3436006_-	site-specific DNA-methyltransferase	K4I3Y2	Acidithiobacillus_phage	4.7e-163	60.7
WP_015914465.1\|3436364_3436760_-	hypothetical protein	NA	NA	NA	NA
WP_015914466.1\|3436752_3436962_-	hypothetical protein	NA	NA	NA	NA
WP_015914467.1\|3436963_3437440_-	hypothetical protein	K4ICN3	Acidithiobacillus_phage	3.5e-62	76.2
WP_015914468.1\|3437569_3439852_-	hypothetical protein	K4HZY1	Acidithiobacillus_phage	0.0e+00	73.0
WP_015914469.1\|3439844_3440072_-	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_015914470.1\|3440068_3440806_-\|tRNA	isoleucyl-tRNA synthetase	K4HZA0	Acidithiobacillus_phage	1.3e-108	75.8
WP_015914471.1\|3440802_3441303_-	hypothetical protein	K4I3X7	Acidithiobacillus_phage	5.3e-69	75.5
WP_015914472.1\|3441310_3441934_-	hypothetical protein	K4ICM8	Acidithiobacillus_phage	4.9e-80	71.8
WP_015914473.1\|3441939_3442785_-	ATP-binding protein	K4HZX9	Acidithiobacillus_phage	1.8e-109	70.5
WP_015914474.1\|3442784_3443543_-	Bro-N domain-containing protein	K4I1D2	Acidithiobacillus_phage	1.6e-88	68.1
WP_015914475.1\|3443545_3443827_-	hypothetical protein	NA	NA	NA	NA
WP_015914476.1\|3443832_3444309_-	hypothetical protein	K4HZ96	Acidithiobacillus_phage	1.9e-52	63.3
WP_015914477.1\|3444320_3444584_-	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_015914478.1\|3444765_3445230_-	hypothetical protein	K4HZX2	Acidithiobacillus_phage	3.7e-16	38.9
WP_015914479.1\|3445226_3446651_-	recombinase family protein	K4ICM1	Acidithiobacillus_phage	3.1e-138	60.0
WP_015914480.1\|3446647_3447118_-	DUF2924 domain-containing protein	K4I3X1	Acidithiobacillus_phage	3.6e-35	51.8
WP_094766854.1\|3447114_3447330_-	hypothetical protein	NA	NA	NA	NA
WP_015914481.1\|3447439_3449152_-	DUF262 domain-containing protein	NA	NA	NA	NA
WP_041839090.1\|3449175_3450024_-	ImmA/IrrE family metallo-endopeptidase	A0A0A7RTT7	Clostridium_phage	6.4e-06	32.3

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. NC_011992

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection