CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Target MGE spacer number	Prophage number
NC_012807	Methylorubrum extorquens AM1 plasmid p1META1, complete sequence	0 crisprs	NA	0	4
NC_012809	Methylorubrum extorquens AM1 plasmid p2META1, complete sequence	0 crisprs	NA	0	3
NC_012808	Methylorubrum extorquens AM1, complete sequence	4 crisprs	DEDDh,csa3,cas3,WYL	2	11
NC_012810	Methylorubrum extorquens AM1 plasmid p3META1, complete sequence	0 crisprs	NA	0	3
NC_012811	Methylorubrum extorquens AM1 megaplasmid, complete sequence	2 crisprs	csa3,c2c9_V-U4,DEDDh,csf3gr5,DinG,csf2gr7,cas14j	11	73

Results visualization

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CRISPR-Cas detection and classification

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

0 : 1719

Enterobacteria_phage(100.0%)

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_043766665.1\|1092_1719_+	recombinase family protein	A0A0A7NPV4	Enterobacteria_phage	1.3e-35	50.5

DBSCAN-SWA_2

5763 : 11975

Mycobacterium_phage(20.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_012751911.1\|5763_6435_-	ParA family protein	A0A142F1W4	Mycobacterium_phage	8.0e-12	32.0
WP_050772747.1\|6771_8805_-	ParB/RepB/Spo0J family partition protein	G8DH78	Emiliania_huxleyi_virus	1.8e-38	30.5
WP_012751913.1\|8862_9885_-	DUF1738 domain-containing protein	A0A1V0EBY3	Caulobacter_phage	2.0e-70	56.6
WP_043768230.1\|10363_10696_+	type II toxin-antitoxin system RelE/ParE family toxin	NA	NA	NA	NA
WP_012751915.1\|10732_11047_+	XRE family transcriptional regulator	A0A0D5BHH6	Escherichia_phage	5.8e-05	31.9
WP_012751916.1\|11105_11291_-	hypothetical protein	NA	NA	NA	NA
WP_043768233.1\|11390_11975_-	recombinase family protein	E5FFF9	Burkholderia_phage	1.7e-29	41.8

DBSCAN-SWA_3

16099 : 19393

Leptospira_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_012751925.1\|16099_19393_-	CusA/CzcA family heavy metal efflux RND transporter	S5VTK5	Leptospira_phage	7.6e-55	22.4

DBSCAN-SWA_4

27931 : 34105

Enterobacteria_phage(50.0%)

transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_082222869.1\|27931_29794_+	cadmium-translocating P-type ATPase	E4ZFI9	Streptococcus_phage	4.9e-91	36.7
WP_080577080.1\|29805_31197_+\|transposase	IS21-like element ISMex13 family transposase	U5N3F9	Enterobacteria_phage	1.1e-44	34.1
WP_043766344.1\|31193_32060_+	ATP-binding protein	U5N3V8	Enterobacteria_phage	1.3e-51	46.7
WP_043768270.1\|32328_32907_+	FAD:protein FMN transferase	NA	NA	NA	NA
WP_076612078.1\|32876_34105_-\|transposase	IS3-like element ISMex33 family transposase	Q8W6R2	Burkholderia_virus	1.1e-104	67.6

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

2. NC_012811

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CRISPR-Cas detection and classification

Crispr_ID: NC_012811_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_012811_1

577825-578338

TypeIV-A

Consensus_repeat	Method
NCGGTTNACCCGCGCGNG	CRT
CGGTTCACCCGCGCGTGCGCGGAGGAGACAG	CRISPRCasFinder
CGGTTCACCCGCGCGTGCGCGGAGGAGACAG	CRISPRCasFinder

8 spacers

csf3gr5,DinG,csf2gr7,c2c9_V-U4

The CRISPR arrays of NC_012811_1

>merge|NC_012811|1|577825-578338|CRT,CRISPRCasFinder,CRISPRCasFinder
TCGGGTTACCCGCGCACACGGGGACGACAGTCCGACGCTTCGGATCCCACGTAGCTGGGGAGCGGTTCACCCGCGCGCGGGGAATATAGGAGATCGGCGTCGACCCCGCCGTGTGCCGATACGGTTCACCCGCGCGTGCGCGGAGGAGACAGGGCGAGGTTGGGCAGGATCAGGCCGCCGGTCGGTTCACCCGCGCGTGCGCGGAGGAGACAGATAACACCCGTGCTCAAACATCGCGAGGGAGTGGGTTCACCCGCGCGCGGGGAAGACAGAGCTGGGTCAGGCTGACATCCTTGGTGAACATCGGTTCACCCGCGCGCGCGGGGAGGACAGATGGACGGATGGGCGGAGCGTATGATCTCGACCGGTTCACCCGCGCGCGGGGAAGAAAATGGGGCGCTGCCGCGCTCGAACTCGTCGCAGGGTGTACCCGCGCGTGCGCGGGGGAGAGATCCTGCAGGGTACGCCGACAGACGTCCACGACGGTGTACCCGCGCGTGCGCGGGGGAGAGCC

>NC_012811|1|1|577825-578324|CRT
TCGGGTTACCCGCGCACA	CGGGGACGACAGTCCGACGCTTCGGATCCCACGTAGCTGGGGA
GCGGTTCACCCGCGCGCG	GGGAATATAGGAGATCGGCGTCGACCCCGCCGTGTGCCGAT
ACGGTTCACCCGCGCGTG	CGCGGAGGAGACAGGGCGAGGTTGGGCAGGATCAGGCCGCCGG
TCGGTTCACCCGCGCGTG	CGCGGAGGAGACAGATAACACCCGTGCTCAAACATCGCGAGGGAG
TGGGTTCACCCGCGCGCG	GGGAAGACAGAGCTGGGTCAGGCTGACATCCTTGGTGAACA
TCGGTTCACCCGCGCGCG	CGGGGAGGACAGATGGACGGATGGGCGGAGCGTATGATCTCGA
CCGGTTCACCCGCGCGCG	GGGAAGAAAATGGGGCGCTGCCGCGCTCGAACTCGTCGC
AGGGTGTACCCGCGCGTG	CGCGGGGGAGAGATCCTGCAGGGTACGCCGACAGACGTCCACG
ACGGTGTACCCGCGCGTG

>NC_012811|1|1|577946-578038|CRISPRCasFinder
CGGTTCACCCGCGCGTGCGCGGAGGAGACAG	GGCGAGGTTGGGCAGGATCAGGCCGCCGGT
CGGTTCACCCGCGCGTGCGCGGAGGAGACAGATAACACCCGTGCTCAAACATCGCGAGGGAGTGGGTTCACCCGCGCGCGGGGAAGACAGAGCTGGGTCAGGCTGACATCCTTGGTGAACATCGGTTCACCCGCGCGCGCGGGGAGGACAGATGGACGGATGGGCGGAGCGTATGATCTCGACCGGTTCACCCGCGCGCGGGGAAGAAAATGGGGCGCTGCCGCGCTCGAACTCGTCGCAGGGTGTACCCGCGCGTGCGCGGGGGAGAGAT	CCTGCAGGGTACGCCGACAGACGTCCACGA


>NC_012811|1|2|578247-578338|CRISPRCasFinder
	GGCGAGGTTGGGCAGGATCAGGCCGCCGGT
CGGTTCACCCGCGCGTGCGCGGAGGAGACAGATAACACCCGTGCTCAAACATCGCGAGGGAGTGGGTTCACCCGCGCGCGGGGAAGACAGAGCTGGGTCAGGCTGACATCCTTGGTGAACATCGGTTCACCCGCGCGCGCGGGGAGGACAGATGGACGGATGGGCGGAGCGTATGATCTCGACCGGTTCACCCGCGCGCGGGGAAGAAAATGGGGCGCTGCCGCGCTCGAACTCGTCGCAGGGTGTACCCGCGCGTGCGCGGGGGAGAGAT	CCTGCAGGGTACGCCGACAGACGTCCACGA
CGGTGTACCCGCGCGTGCGCGGGGGAGAGCC

Protein	Signature genes	Signature genes Name	Protein_function
NC_012811.1\|WP_003596621.1\|584309_585041_+\|hypothetical-protein	unknown	unknown	unknown
NC_012811.1\|WP_012753905.1\|568674_569352_-\|dTMP-kinase	unknown	unknown	gnl\|CDD\|184429
NC_012811.1\|WP_162094049.1\|586010_587219_-\|transposase	c2c9_V-U4	-	gnl\|CDD\|223747
NC_012811.1\|WP_012753915.1\|578458_579205_-\|hypothetical-protein	csf3gr5	mkCas0093_csf3gr5_CAS-IV-A	unknown
NC_012811.1\|WP_012753923.1\|587390_589322_-\|hypothetical-protein	unknown	unknown	unknown
NC_012811.1\|WP_012753917.1\|580940_581453_-\|hypothetical-protein	DinG	COG1199_DinG_CAS-IV-A	gnl\|CDD\|224120
NC_012811.1\|WP_012753904.1\|568230_568653_-\|hypothetical-protein	unknown	unknown	unknown
NC_012811.1\|WP_158022471.1\|583366_584035_-\|type-I-E-CRISPR-associated-protein-Cas6/Cse3/CasE	unknown	unknown	unknown
NC_012811.1\|WP_012753919.1\|582585_583380_-\|hypothetical-protein	unknown	unknown	unknown
NC_012811.1\|WP_012753907.1\|569683_570301_+\|hypothetical-protein	unknown	unknown	unknown
NC_012811.1\|WP_012753908.1\|570316_571615_-\|hypothetical-protein	unknown	unknown	unknown
NC_012811.1\|WP_012753909.1\|571635_572466_-\|hypothetical-protein	unknown	unknown	unknown
NC_012811.1\|WP_012753913.1\|576228_576999_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|181619
NC_012811.1\|WP_012753903.1\|567554_568220_-\|hypothetical-protein	unknown	unknown	unknown
NC_012811.1\|WP_012753911.1\|574774_575263_+\|hypothetical-protein	unknown	unknown	unknown
NC_012811.1\|WP_012753910.1\|572724_574581_+\|hypothetical-protein	unknown	unknown	unknown
NC_012811.1\|WP_012753916.1\|579201_580944_-\|hypothetical-protein	DinG	COG1199_DinG_CAS-IV-A	gnl\|CDD\|224120
NC_012811.1\|WP_012753918.1\|581452_582571_-\|hypothetical-protein	csf2gr7	mkCas0162_csf2gr7_CAS-IV-A	gnl\|CDD\|187837
NC_012811.1\|WP_050772740.1\|575272_576076_-\|hypothetical-protein	unknown	unknown	unknown
NC_012811.1\|WP_012753922.1\|585052_585790_+\|hypothetical-protein	unknown	unknown	unknown

>NC_012811.1|WP_012753913.1|576228_576999_+|hypothetical-protein
MADKAGETKSVGSALKVRAFVSKGTSKVKAAYLRVRALRAAPLDRKVLAAAAAGLLIGTALGFAGASRDHYRDEMQALRGEIGAGRGETARIVAMLDRDRTTMAEIRERLATASSEAERRDAVSSDRSERLNRDLATLHEDLRARSEALGREQAERIADLARMLDRRFQEAALSQPRVEPTRTGSIGGAAIPATIEDWALREVLDGVATIQDRKRRVIEVARGDSVPGVGRVESVERRGRTWAVVTKQGVIAPQGW
>NC_012811.1|WP_050772740.1|575272_576076_-|hypothetical-protein
MVGRRGDTGTELSTVPVIAVRAVLDPQAAESPEALRMAEAAGLPAGGIWNRFRPWAQVEDGEMAFGRHMIQSTGAYDDDREREPDPAEPAVAYVWGIDGIEAVDETLDGLERAGLGGRTSNDIRDVMRQLLGMPEAAMFAARRAASRRVAGILVLRRTVSIGVVGAPYASYSACIESYAVLAGGTDLRASLLAAAGMQIQADLLTLADGLRRAGHGGEVFCSVSEAPSAKGAVGTLRSVADLAADLVKHRYREATEKVGFTTFSAPR
>NC_012811.1|WP_012753911.1|574774_575263_+|hypothetical-protein
MSDRYVDSDGLAHEAMTFSEALEIVHELAQFNVLGDDHVAGAPDLATEQRRQNEAVNMLHDLVVNYSDQLDGSFQLPEKAAERPADRERLPSDADLSVPSNYLRLCLDIATQAYDPDAAKQNPDLEDEVLRQGQALDLGWDLLDLHGRDLDLSITVVPGPRA
>NC_012811.1|WP_012753910.1|572724_574581_+|hypothetical-protein
MAAKGYDSLPLFGIGPLHRIASRYEADGRVALVGPDGSATTMTETDFEAGFQVVVADAGRALPRDASLVRTATPPVGAVRMSEGFEPLVALDVPLAVQAKALLDRPEEAAHAVHLLDETKKVLRASVVPVVGYVDAAAANAVMTCAAAPAAKRAEAVAAACAKAAADWAPSNFADRFCRDTGIPRTMWKPVRSYETSAAANIASMMDRYAGADLASCLDRAAVMVLSREYAEVVGAAEIWLEGSDLLGTETEEAAQPSPDTPQWALDWRRAWFGDGRWSCAHRRFGAFDILVFEMSDMFQVVSWPTEAGAAAAPRRADEAAPYLAGPFYSLDVDAALPGGLEEAHLIAEEGFGTPVSMPWDRFLREFRPFPARVERWIPAQQVRWLDAEEANTTAGLVRADRWGRPTIPCALPLAAQMFTLRNLGMDENHIPHILAEGDARLLDPDTPEGQLVDALLAGTVANADDEDFANEEALDELLDRNQERLRAELAERCRGQAPRVVAKSLGIPPHAWRSRRGMPEREMVAMLVAARDLFGPWETKIADEPGALVIDAEHAGPLKDWLVNGEMVGRRPTPHGDLVGVRREGCDFLWTEAGGDLTVYGWRSPPQAGAPAGAVLN
>NC_012811.1|WP_012753909.1|571635_572466_-|hypothetical-protein
MKYRVTVEWKDCDERDVVRLRAADPATACAEAVRRGEDGLLQTVSASWDPEPAYVTAVSDADGRSLPVPRAFEEGAVHLGEDWPKAHAAAVLVREMKLAAAAAAGSSQGVAIDVVLRTFLGSPMEVATPPDDQGAYSVVVAWLDKANVLEIEVEAESVAAACAKAVEAAADGGATLVDFDTPSEVFVLALVEGDEPSAGEVIEHSLDVPAPWSEGWRLHARHLRALELFEAGAADALHAFRIAAGGREDLLEHVARAEAAFAAIPSPSTVSAAPSI
>NC_012811.1|WP_012753908.1|570316_571615_-|hypothetical-protein
MPVPTQEQFDAAPLYRAIVPTPEETERDWSAAEIVVGGLTLSRTDTDVGGFEYRLEGVPIAVGAPHEEEGWHGFRVQYLSSDAETMIHADDRDEALRRLGRLVERAVFTQDEILFMRLRDRDVEVDDIVDAAEDAFPELREPAFGEPVRGIRDGGRLWLQGAEAPQAWFEIRNDLVRCGEEGEVLCPAGLPILAQIDLLRNDPGAVRHLEDVRAIRTSIGDAARIPVVDTRYALHFFDLRNTGLADEVVTQEALDTYGRVGVAHYGDEEVAGLEAEVPQVVDPSVVPHDRTAERYIGDIMREAAGIHVHFEEIRGGRPYRDPIIRGVMREQMTPYLGGFPMEHVMASRAPRDPEGFAAFYNFWSEGEIVMEVPVQEHPSQPGYRTQPGHVFRRDGYDALVFADDMNLYAYAFPSPPDVVARPDEQETYAPRM
>NC_012811.1|WP_012753907.1|569683_570301_+|hypothetical-protein
MAERTFDDRGELVAMEVPVTGRASRTVLIRGEGLPDLIGVGAVDLPDETWLSIENRGREGRLYTQVGAIRQGVLALAGTRTTSAMLRGGHTVGQGAAAEEAVGGRLSMTEPGGRFPDTASWIGVKEDGTAFMVVANVGWDSFQLRAALAPYVAGAFHLQYLWVGTYEAAPELSIFGWELSMSRPAEPFPAPETEEAPRSPGAPLV
>NC_012811.1|WP_012753905.1|568674_569352_-|dTMP-kinase
MSDLPKRHPEGVFASLEGPEGAGKSSQINRLAERMRAAGREVVVTREPGGCKGAEVLRNLVLSGAVQWDPRTELMLFAAARREHVVRTIAPALARGAVVLSDRFSESSRAYQGAARGVGTALCDDLERIACDGILPDVVFLLDVDPVVGLARSKARATDSTMFEALDLEFHRTLRQAFLDRAAERPELFEVIPSMDVAATADAVWAAFLRRFPQALPRDLCAGGR
>NC_012811.1|WP_012753904.1|568230_568653_-|hypothetical-protein
MDNARNKRRFEFDLADIPMLAHALSIECGTWLGCDRAKYVRAKELHDLVAAEVPACSKHFDADDWQDFCRRISAGAAYEIVHRRRGWSWDSPDGEIVVRIEDKEWRSHRSGHPPEAEAIAELRAFLEEYAPMEPAAGPRP
>NC_012811.1|WP_012753903.1|567554_568220_-|hypothetical-protein
MTTHVMPEFVTFTGPDDLVDVDRMVAISVRAPVEWGILFSRRRQGMGRYPSLGLLPKLASPGLRLAAHVCGSYAEEIVATGACLELETLLANSGLRFSRFQINTTLPLDTRLLASFATRMSGARAIAQCRDIFPDDPSIDWLHDVSAGEGIVPAARPVPEQGIFGGYAGGLGPDSVAAQLAAIRKTHPAKQRFWIDMETKVRTNDIFDLGKVEAVLDAVYG
>NC_012811.1|WP_012753915.1|578458_579205_-|hypothetical-protein
MNASHRPIVVEAVLRTPISVTDPIHLDGVLLAAREKRHGPGSRGRPLDCVAWDDGFHRCSASFLVSDELGGVATVATTRVARLDLKSRDGELFVPPDGSEKISRKSREDVIGPMSAFRGVTRDFEVATGVRSLVWQVLGDPEGMLDLLSEIRCVGRMYTTGWGQVDEWLAHDCAADQAFCGAAVAGRPMRNLPAASAARFGIDADLTYPGRIEPPYGSRFDLVPIVAPTRIDLTGTTQAARRTFAFDA
>NC_012811.1|WP_012753916.1|579201_580944_-|hypothetical-protein
MIRTSPKAAVAALAGTIDLWRREHPEMADQLPLEDLDQWRLDAVCSHDEHLAYEAFRSQAQDADCLVMTQAALVVGLKARSTFGDNRRIVGVVVDEADRLEDAARSVLERRSSLADLDRCRQSIFDVVNRDDIGISPGVRTRILDLAMDLPGLIAPVHAFCGETRSLRDREIGGSADQLVVKGDEPWLTHVAGAATALAKTAAAMRSTRIPALASVADDVTARASIHSEFVACAKDPDKRLGRTFLVFSPKRGFPSVLVAAKYGSRIVQRLWNPASYDETMSALTPATIFTSATLSQPGLRGAERLSDMSRMVGLDWTPERLQVDLSGQHAPKKYGRVERFVLAHPSAPMPPRRSGEDEDAAFEADAAAYGAHRAACIVEAADRPPVSGRKRILVLTTSWFDNDLIAGALPERLANQLIVRQRGQSLAEVLELFRASEDAILVTPGAGEGFDAPGLIGRVLIPRLPFSPPEDAFGLPLVWQTENGTKASSDVVRMMRRLKQMIGRAIRVSDDVAEIWILDPRFGLPSLVQRRELLTPARQAKPVYHHCVPARFRGVLDEAEVFSPAEPAKARRRAAGGRR
>NC_012811.1|WP_012753917.1|580940_581453_-|hypothetical-protein
MAFDTTAWFENPAPHIEEALGEGGRYLELGLPHVVSPEQIAYATDVAQALTRSVGNGGLVAMPEAETGTGKTRGYLIPALLHATATGGRVLIATYRIDLRSAIVEREGPGAAAVVEAMTGRRPSIAPLMARSHFASPSRSEGLADRIAQEKPLAAARSAPSPPGHEHARN
>NC_012811.1|WP_012753918.1|581452_582571_-|hypothetical-protein
MDIRLEGTITATSAISVSRADARDRDKGVVMQRIMEAGTATFRPVIAGETIKGALRAAANRAVLARLGTRYDRILPLYRNMIGGIKGRAKQEPIDILKIRGLRSANPIASLFGLAEPMWIQGHLQVQWAIPRTDDCIAEIGAGARRDPATVDPTAFDALEPSEQTKYFAYQGTTREVSEIRGRRTAIKREIAKIRSKDVAEPGDAARIEQLAMEDKVLDVQIGTLRSDQDIAETVGRPLGTRKAIAAGTVMDHALILTGDDVSDVEVGLLLATLEEMSEECRIGGGRSAGHGFFEADYDVKIRDRKGAPWHSPGRLKLGAFKLEIPSDPLLERARRAFEQALSDPAANGIDVMFGGPAAEPVEAAAQIEEVA
>NC_012811.1|WP_012753919.1|582585_583380_-|hypothetical-protein
MSSSEGVSEVRCGSPEWRLFHERVGRYFEKSEAGDASGTCAICGVDLVGAVKGSSGPTCPPVRSAGSKRGKIEKGERIVFDPAVAARTGKSALTNVGCVVLIEPDRCSVATNVVPSRPLPADMTVSPVEPGSTGRFLAELGRRPPKAPFLLIEFDNKIPPLVLSQSPTRAAWCGGSAVATVDLTAIPRVAALAERLGPKLFATLASLKDRLASAGLNEADGKVLADLRTQGVITPDDLDLVPGRSSRLFSIVDKATAEAVVAQV
>NC_012811.1|WP_158022471.1|583366_584035_-|type-I-E-CRISPR-associated-protein-Cas6/Cse3/CasE
MANMTFPLELAVRTAREVAPSTAEDMGYVVKTMVGETYGRDAIKPWRIAAEGGGKVRIVGWIDAEQGVPVPKSRFASEIEVGFVPYEARKGDEVLLDLIVAPTQKIELPGGRFREVDVAEAAKDRGALAVYADWLKLQFSKPDTGCLPIGIPSFVETSQDRGVRKAIGGKTTTIRFPRVHALQKVRIVNQRAFERMLVAGLGRQRAFGYGCILPRELCDVVL
>NC_012811.1|WP_003596621.1|584309_585041_+|hypothetical-protein
MSRLVLSALAGVLTLAGAFTDAAWADEGCKPVDGNALPAEARIGRKAWIFDTVNTHAFEPPAEWTKADAYELIGPGNWVKSAKLPRLEYGQPVEIVEWRQVGAGLGQYQVRLPDGAERAVHAQTVHLFEFWRCPPSTLLEKRLPNGPTKPAAQYMPSAWVRIANPKATAVDGARRWIPEERLAKIAFAICNNYEPNIKRFRYWEEPLTCQGFTPGEHGGLSFTIDPSAVETISPTSMKILFSS
>NC_012811.1|WP_012753922.1|585052_585790_+|hypothetical-protein
MAWKTAIAPTLALLTSLLTSLLGAAAARADGCSPVDAHRIEPSQAAGMKVWLFEDRGGPGPFRKPFQWAKAATSRPEPGGTYAPTGAMLPYGQAATVVRFVRQGTMHGLYEVRLSDGSTHLVDRQVVKFHPFWQCRPEKLLDPTRDRGMRRLDRRLVDAVWVRVRNPQAVGLESWGAPTAPGELGQLAFLLCNNFDTARPGDPASAYDTSCQGFAPGRDRSKSYRIRHEDLETVSPISMRIIFES
>NC_012811.1|WP_162094049.1|586010_587219_-|transposase
MTYKLYPSPVQAAALERVCDLHRALYNAALEERIEAYRKAGRSIGFADQCISVTAIRLDDPAYRVLNAQSLQVTLKRLDRAFQSFFRRVKAGQAPGFPRFKGRDRFPGFGFKSHGDGFRFTPGQGWRNGTLHLSGIGEMTARGEARTPGELVCADVQRRAEGWFLSLVVSCEPHRERMGESIAGLDWGVETYATLCTGPMQFGEIENERFLAVEQEALKEEQRALSRALRGKRSKRAAKARKLIARRSRHLANRRKNRTHQVTARLVRGHATIVTEDLSVRNMTASARGSVEEPGRRVKQKAGLNRAILDTAPGSFLSHLRIKAEEAGCVLVLVDPRRHRPSQTCPVSGEVRKEGLGERTHTLPDGRVISRDQASAWVLWNIGQELAAGASPETALGAAIAA
>NC_012811.1|WP_012753923.1|587390_589322_-|hypothetical-protein
MVENSYAGYVSGLYTDLQGRLVYYAAFEAEGGVVAVALASEGPMRTVGDMTCLEGATLAGIGPVGMLAAQLVVDTDLKPHGRQKLRASALAARALGYVASAGGPEVLPPEMRCERWHAFLARAGAGVFAAWSVSVLSLAQGEEAGSPVLSVLDRIVTRWPVFARVLKDREAPLPAEVLKAGDDRMAEALVDHLFGHEAAALWVRERAVEFVRSLEGIVADVEVVDMVDLAGRLPVQFHPRGLSDLQGFDGAAALFGEMSRRHLAPADVCFMFASFAEDWTTAPPRAVPDFGDGGEETAEEACDLIADHLAAMTRRFGVPAWLEFAVPDFGNLPARTADSLVLSVVLALGEAGGSVSAPLAELFLKDIDLARLLRSLRISPTASSPPPGAAHVAEVERNFRDAEAAGEFAGRVAPRLRVGGARRIGIELVDSGFGRDLDLEGIRNGVGARGTASADRPRLRTGTYVVPPMNRPRNPGSQAPRIRARHVAGSILAGILVAAAVVVFSRPQGVTASVETGETAVQTRAAGRSPDFSHLSRLVERRAEMVRVAKLNPAPCPGDDGPGRICGRFGDLTLVVSERAATKPTIAGYVVEGRHPVEVFAWNAGIFRNPSAAWTSHLLQTLDDEAGRASAGIEASALAGDGR

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Crispr_ID: NC_012811_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_012811_2

620384-620470

TypeV-U4

I-E

Consensus_repeat	Method
CCGTTCCCCGCGCGAGCGGGGATGCT	CRISPRCasFinder

1 spacers

c2c9_V-U4

The CRISPR arrays of NC_012811_2

>merge|NC_012811|2|620384-620470|CRISPRCasFinder
CCGTTCCCCGCGCGAGCGGGGATGCTCCGGTGCGATCACGCAGCGCTACCTCAGCGACCCCCCGTTCCCCGCGCGAGCGGGAATGCT

>NC_012811|2|3|620384-620470|CRISPRCasFinder
CCGTTCCCCGCGCGAGCGGGGATGCT	CCGGTGCGATCACGCAGCGCTACCTCAGCGACCCC
CCGTTCCCCGCGCGAGCGGGAATGCT

Protein	Signature genes	Signature genes Name	Protein_function
NC_012811.1\|WP_158022501.1\|626539_628345_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|226875
NC_012811.1\|WP_012753949.1\|606456_612552_+\|putative-Ig-domain-containing-protein	unknown	unknown	gnl\|CDD\|227511
NC_012811.1\|WP_012753958.1\|619384_620245_+\|hypothetical-protein	unknown	unknown	unknown
NC_012811.1\|WP_158022473.1\|614843_615029_-\|hypothetical-protein	unknown	unknown	unknown
NC_012811.1\|WP_043767695.1\|624144_624561_-\|hypothetical-protein	unknown	unknown	unknown
NC_012811.1\|WP_012753965.1\|629202_630330_-\|transposase	c2c9_V-U4	-	gnl\|CDD\|223747
NC_012811.1\|WP_012753952.1\|614127_614448_-\|helix-turn-helix-transcriptional-regulator	unknown	unknown	gnl\|CDD\|238045
NC_012811.1\|WP_043767699.1\|625565_626408_-\|GIY-YIG-nuclease-family-protein	unknown	unknown	gnl\|CDD\|198387
NC_012811.1\|WP_012753967.1\|631417_632608_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|271164
NC_012811.1\|WP_012753964.1\|628617_629085_+\|hypothetical-protein	unknown	unknown	unknown
NC_012811.1\|WP_158022476.1\|624922_625267_-\|YkgJ-family-cysteine-cluster-protein	unknown	unknown	gnl\|CDD\|223799
NC_012811.1\|WP_012753951.1\|612890_614144_-\|HipA-domain-containing-protein	unknown	unknown	gnl\|CDD\|377920
NC_012811.1\|WP_012753948.1\|605963_606188_+\|hypothetical-protein	unknown	unknown	unknown
NC_012811.1\|WP_012753956.1\|617056_617887_+\|hypothetical-protein	unknown	unknown	unknown
NC_012811.1\|WP_012753966.1\|630380_631349_-\|hypothetical-protein	unknown	unknown	unknown
NC_012811.1\|WP_158022475.1\|618072_618984_+\|hypothetical-protein	unknown	unknown	unknown
NC_012811.1\|WP_158022474.1\|615557_617039_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|274760
NC_012811.1\|WP_012753969.1\|633318_634200_+\|porin	unknown	unknown	gnl\|CDD\|226163
NC_012811.1\|WP_043767986.1\|612633_612879_-\|hypothetical-protein	unknown	unknown	unknown
NC_012811.1\|WP_012753959.1\|620562_624141_+\|DotA/TraY-family-protein	unknown	unknown	gnl\|CDD\|275142

Protein	Function_ID	Function_description	E-value
NC_012811.1\|WP_158022501.1\|626539_628345_-\|hypothetical-protein	gnl\|CDD\|226875	COG4469, CoiA, Competence protein CoiA-like family, contains a predicted nuclease domain [General function prediction only].	0.000355657
NC_012811.1\|WP_012753949.1\|606456_612552_+\|putative-Ig-domain-containing-protein	gnl\|CDD\|227511	COG5184, ATS1, Alpha-tubulin suppressor and related RCC1 domain-containing proteins [Cell division and chromosome partitioning / Cytoskeleton].	7.04486e-19
NC_012811.1\|WP_012753951.1\|612890_614144_-\|HipA-domain-containing-protein	gnl\|CDD\|377920	pfam07804, HipA_C, HipA-like C-terminal domain. The members of this family are similar to a region close to the C-terminus of the HipA protein expressed by various bacterial species. This protein is known to be involved in high-frequency persistence to the lethal effects of inhibition of either DNA or peptidoglycan synthesis. When expressed alone, it is toxic to bacterial cells, but it is usually tightly associated with HipB, and the HipA-HipB complex may be involved in autoregulation of the hip operon. The hip proteins may be involved in cell division control and may interact with cell division genes or their products.	1.0775e-45
NC_012811.1\|WP_158022476.1\|624922_625267_-\|YkgJ-family-cysteine-cluster-protein	gnl\|CDD\|223799	COG0727, COG0727, Predicted Fe-S-cluster oxidoreductase [General function prediction only].	5.45327e-05
NC_012811.1\|WP_012753969.1\|633318_634200_+\|porin	gnl\|CDD\|226163	COG3637, COG3637, Opacity protein and related surface antigens [Cell envelope biogenesis, outer membrane].	2.56344e-09
NC_012811.1\|WP_012753965.1\|629202_630330_-\|transposase	gnl\|CDD\|223747	COG0675, COG0675, Transposase and inactivated derivatives [DNA replication, recombination, and repair].	1.91298e-35
NC_012811.1\|WP_012753967.1\|631417_632608_-\|hypothetical-protein	gnl\|CDD\|271164	cd09256, AP_MuD_MHD, Mu-homology domain (MHD) of a adaptor protein (AP) encoded by mu-2 related death-inducing gene, MuD (also known as MUDENG). This family corresponds to the MHD found in a protein encoded by MuD (also known as Adapter-related protein complex 5 subunit mu-1), which is distantly related to the C-terminal domain of the mu2 subunit of AP complexes that participates in clathrin-mediated endocytosis. MuD is evolutionary conserved from mammals to amphibians. It is able to induce cell death by itself and plays an important role in cell death in various tissues.	0.00516321
NC_012811.1\|WP_158022474.1\|615557_617039_+\|hypothetical-protein	gnl\|CDD\|274760	TIGR03743, SXT_TraD, conjugative coupling factor TraD, SXT/TOL subfamily. Members of this protein family are the putative conjugative coupling factor, TraD (or TraG), rather distantly related to the well-characterized TraD of the F plasmid. Members are associated with conjugative-transposon-like mobile genetic elements of the class that includes SXT, an antibiotic resistance transfer element in some Vibrio cholerae strains. [Mobile and extrachromosomal element functions, Other].	0.000595055
NC_012811.1\|WP_012753952.1\|614127_614448_-\|helix-turn-helix-transcriptional-regulator	gnl\|CDD\|238045	cd00093, HTH_XRE, Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators.	2.77128e-08
NC_012811.1\|WP_043767699.1\|625565_626408_-\|GIY-YIG-nuclease-family-protein	gnl\|CDD\|198387	cd10440, GIY-YIG_COG3680, GIY-YIG domain of uncharacterized proteins from bacteria and their eukaryotic homologs. This family includes a group of functionally uncharacterized proteins from bacteria and their eukaryotic homologs which are present only in metazoa. These proteins might have nuclease activities and possibly be engaged in DNA repair or recombination, since they share sequence homology with the catalytic GIY-YIG domain of bacterial UvrC DNA repair proteins. Distinct from their prokaryotic relatives, the eukaryotic homologs contain an N-terminal extension that includes the region of approximately 3-4 ankyrin repeats, unique motifs mediating protein-protein interactions. Some of eukaryotic homologs do have an additional LEM domain located between ankyrin repeats region and GIY-YIG domain. The LEM domain, found in inner nuclear membrane proteins, may be involved in protein- or DNA-binding. The different domain composition of the eukaryotic homologs suggests that they might participate in interactions with multiple partners and implies important cellular function.	1.40629e-30
NC_012811.1\|WP_012753959.1\|620562_624141_+\|DotA/TraY-family-protein	gnl\|CDD\|275142	TIGR04346, DotA_TraY, conjugal transfer/type IV secretion protein DotA/TraY. Members of this protein family include transfer protein TraY of IncI1 plasmid R64 and DotA (defect in organelle trafficking A) of Legionella pneumophila.	2.96208e-71

>NC_012811.1|WP_012753958.1|619384_620245_+|hypothetical-protein
MYAPDHKSFEGSLDQESRDYAFPLLTDSCERSFPITDRQALNHFLVYGPKSAARSRLLLDIAEAKVRRGSGLLHVSTLNDDIQTEIHDRTRAWSGFGQTAVSTYSGTDDTTSSSLLDKVFDDRWILFVRLPDPAKDAEAATKAEARFCADLMSLSKRVGEDFILSHWRRQYNGGARIFTHAPTPIVFDDASRYVGDLSGMQAAMFKGLGFSAIYGVEDDAAFGANDPKAAADVLRNAMTKVVMGDSIAVTCGLTPMPRLGAEFFRRTASVRDQRSRPRTLSQATAG
>NC_012811.1|WP_158022475.1|618072_618984_+|hypothetical-protein
MRSHVVERVFALGQSAAALETGVPRTTVQRHVEAWCASRELEVLDAAPDFLLLEPVRICGIDRVMIVDVDREALVEILTAGEAVRGWLCDPGRPSALRICTPLDPSIVRLVGSALPNVRTMVSPSAAARAVRTEADLGFRFLRRRGKASGCNGMPTASEFQRSLAREGAPGPGWPRMVAALATAARAALDLLGSRSREEGERRWAETELAAAGAERILRWLRVWREPVLEGLDHAFVNATAKLAAGVRRAIARRRPVLGFTDLRAFVLLRDFVRRSVPVPPGFPPRAISEGRPLAGLAAILTP
>NC_012811.1|WP_012753956.1|617056_617887_+|hypothetical-protein
MKIELIPTVGAAICGGCAVLVAEPVMGYLISHVNLVCMSTSAIILAGAASVGLRRRRAPELKPNFGNYSPPLSAAEWLAANNIQADADKSHAAAMIGSALRQQLISSTLHDVRVEALVLCLLKAGTSKQGGCELLDELAVAATGTDPEGKTARFLLRHDLRTDPVVKDLRDAIRAHHGFAATMLLAALERARRSGRCPPSAMTWLKQVDRSLWYAVSNLGRSAYHVEGLAAIAHYCAEITLGKSLLQPNVDDAARSLIRIHVERRDVADAPRAEAA
>NC_012811.1|WP_158022474.1|615557_617039_+|hypothetical-protein
MLGNEGWIMGTWAETKEHVGRAINSLTGSRTQTATALAALALPAILSPTAAAASAAAAGALLFARSRMLRLSFATTASRHDETYPIGTMEDGTPVALNAQQMNSGMLVYGTTGSGRTEALLGIAQGMLAKGSGMIFVDGRGDVSVYANIFVMAAAFGREDDVLVVTPAIHGAANLAHTFNPLQTGSLEQLKILINDLTEPKQTESYWHSRTTILTDIVLEALVFRRNAGNATINAEVFRDAFDFENVLLLAEDRELPEFLRRRACEYLRMLPGFQRERGPKQAQSTLEHHLYLKMYAMKAFGTLTEVGWMTSAGQQVDLEDVLSNNRILCIMLPSLDRSPLQADICTKAVLASLRMAMTSSAKVSTLDYTTGRSKPFPIILNDVGCGTSHSLMAIACEASSLGLSMIYGFQDEHCPSRLCGETGTSLVANANVRIQLSSEADGRMTLQYGGSSLNLAAPLPCTHQRSDQTQAFKNTVYLAPADLVPLTMCAAD
>NC_012811.1|WP_158022473.1|614843_615029_-|hypothetical-protein
METTDRKERTDEIADSTSRTIEGETCEGVGRYDLDDFLRLVAAYRNLGFGLIFVAADQAPA
>NC_012811.1|WP_012753952.1|614127_614448_-|helix-turn-helix-transcriptional-regulator
MQTTAILSTDELESLRLLSERVRLARLRRNLTQAEFAERMGVRRLTVVSLEKGRPGVTISTLLKALTVLGYTERLGDLLASDPIGEEMEIATGRKRAGGRYGVADF
>NC_012811.1|WP_012753951.1|612890_614144_-|HipA-domain-containing-protein
MWQTSKTGRIDRLVVFRWLAGSYVPAGELTFEGAGVKRLGRFRYAGSYLKREKAGEIDPIGLPLVGRSFPGAPEELPLAFYDAGPDGWGKQVLNHAFPKSVLSMPEYLALGGTDRTGDLAFGPTPEAGPQTWTPAEEPLVALPRETDDLEAIMAAAAAVDEGGGAKHHFTLLFRPSADVGGARPKARIRHEGRQWIAKFPATTDRFDDPRVEAACLDVAAAAGLPVPDRRIVEAGGRAALLVERFDRAPGINGSPYGYLSAATLLKQPPTSYGTDRTYVDIADAARRIGVPGAVEAAFARLLLNAYLHNTDDHLRNHAFINRGERWEFSPVFDLVPHPDVRRHVCAPAKGIGPAWDVDAAFEAHRSLKIAAEDAAAIRDRVVQAAKGLTGFMDARGVSRKDREYLRDAFPAAIEFKS
>NC_012811.1|WP_043767986.1|612633_612879_-|hypothetical-protein
MVQVAIFVAVMAVGQSLRWGMNPTIRPKRPYRAVEYWRHGVRLADAEGERISAAILSAPLPSATQPRVLASPRMRIAAEKL
>NC_012811.1|WP_012753949.1|606456_612552_+|putative-Ig-domain-containing-protein
MRHSFRSFVAVLMAVAQPLEATAQVAGPIYDFSPTGRYFRYRVEGVDVTGVNVLVRGPTEVVLTGAATSIETRVRGGAAPYVFDVASGVLPEGMTLNPSTGAASGGTTKAGRYIFTIRATDANGGTGTSLPYTIVVQNQKLEVSRSPSLSAPLGKAYSDKLGATGGRQPYTWAVAQGALPPGLVLDPATGALSGAPTSLGQHLFRAQVTDADGARALSTEYVLFVDDESLSLSGSAPAKGQVGANFAGRFAAAGGKSPYAYTLSGLPLPPGLALESDTGWIKGTPSAAGEYGGLRVRATDATARFVDSNYFSVSIVAALVASWSGTKAAVGTNYSSQVLRTGGRAPYAFSLASGTLPPGLTLRSSDGLITGAPSAAGTFGGLVVRVSDADGRVAHTPSFGIEVSNELTVVGLPSRIGTQGEPYSSSVAVGGGLKPYAFRLGAGTLPGGLTIDGSNGTISGVPASTGLTEGLKILVTDGTGRTTVSDAFSIEVRDRLFVSTASMPAYHSVNTDYAGTMTASGGARPYRFSIAGTLPTGLFLDAQSGRVLGTPKNTGTYGDLVATVRDAEGRVANSPKFAVTVSGPIAVQTPASYATVNMSFSSVVATTGGRGPFVYTSRSRLPDGLFLDPAYGIIHGTPTAIGTTPGIVIDVVDADGRTGSTPPFDFIVETPASVVEIPQRAKIVMGVDTHTSAPVVTGGTAPFTFALKGNVPSTLKIDPKTGAIGGITHDPAGVYYSSLRIVATDARGRSSESDPFAVLVVGPLAISYASTKLAFDLQNNFQRYPARIEGGCGDLRWDSSGYTPPDIGIDLYQGSIGVLRSLRFWDEGSFPNVVVTAQDACGVTATATVDIDVQDSQPNAMLNGPANINVPVGQIVRTSPVSTGGLASNRFALSGSTLPDFLSLDGTTGVISGTIPASTPSGTVWTFDLIVTDDFGRRAIVPRLKITAVTPPTLSYSNGGRLPFQTTTWNQHVPAVVGGCPVSSWQTTSGNLPQGINLGTNGTIQRDGGQMSAGTSSPVTITLLDTCNQTVSTDVTIDIRTGGVAATGPSQQGLVVGEASHTDAMTVTGFAPDAVYTLLGGPLPPGVALDANLRIAGTLSSSASPGTTYGTFVYRVTDSFGRTATTPAFALFAAAPPQIGYAASTSTSTGSTLSLRPNVSGGVTPYTYQLTGTLPAGLTFSTSSGNIEGSPTAAGSASNLTVRISDASGVTKTSNAFAISVANPLTVTGSPPNGKTGTAYSYTFSATGGQGGLTFSTQSTLPAGLSLSAGGVLSGTPTRAGTYPFVVSVSEASGRSSSLSVSLTVAQATTAGTWMSWGTGQLGDGLISSVSYVPRQASALQPSLSIAVTGDGTTACGIGADKRISCWGNNKWGKLGDGSDVTAPESRTSTVTPVMLSLYDNTWTHVVAGSNYFCALNASGSVYCWGPNGSGTGQSGIYSTPMLVGSGYVRLATSPVGRTTCGIKNDGYASCWGAIAGSSMSNVQSPRTVPSAGLDTWSRIAPGTSTICGIQTDRTLWCWGANASGELGKGYADGTSVYVPTKIGTKSDWAEVVNNGTSICALDTTGSGWCWGSNAEGQLGTGGSRGISAPTPVAGGHKWNKLVASGDGAICGINESNSLLCWGRNTTGQLGSLDTGNQFVPTVVAGPITNFSDVAVSSVTYALPADGGSSARTAGNLYSWGWSGGLGFRSTSDAPTPIVVGNKNDWVGTTGGLLFGCVSDVAGYGFCWGDNAYGQLGNSGGGGTVPTAISGGMTWSQLSAGQDTACGVTRDKELFCWGSNEKGQVGVNMTSPAYYAPQRVSVGTSYQKVFAGQFTFCGLGTDSTLSCWGENRYSLIGNSTYSTAVPAYAPKPVSGGHTFRTVAIGTTAACAIRNDASIWCWGQNDKGQYASTAVTSGDPVAAGTSNGQWTSIAAAGSSFCAIRTDGRLFCWGENPSVGALIGDGNASSKLNAGAVTSPREVAGGGTWTSIVGALGQTAFCGTQTGGQTKCWGQNFGAIPNASGNPTPMTSPLQAGGLAGIGLGMRNGYGIR
>NC_012811.1|WP_012753948.1|605963_606188_+|hypothetical-protein
MASPELTILELASEVTDLRLQLAEIQEQCIEMAVDAGQLHEEIRTLRRELKTTRRERDGYLERLCGRGGARTAA
>NC_012811.1|WP_012753959.1|620562_624141_+|DotA/TraY-family-protein
MADQRNRSGTDLGDLGRDTLVDDLVGRDQWRRSKLGYLTGVGPIRQSMSTIGRTVGETGRTWRALCRALFRRDSDARAVNVDDPAERFEASMFVHGRTEADLVALQRRSHHAFYLYAVLMVVAFVLGTLSHKFVPSSISIPVGLQILFGLAVVPMLGAFVFRWGYTNFIVRRRSYLPALAYLGSGDWFPQLPASAVVVRRRRAATKIAIAAATVAVGFGMLPTDAFAQNPPAPTGNGLAQAFDIFKTPGSDDLFMNLLSLVLPNVGPVPGLTGQAAAGSPAHNSLSMGLMIFSGILLLVACTMVAWHTITGTVMSAQTGKVLGERWSQVWSPARVVVGLGFLIPISGGFCAAQILVLYLVAWGGSAANMIWVPYVQAISSGSASTAEATAVTDKASFIANLPGTYDAVRQIAERELCYETNKIVFQRSGTNLAWNGIPETLKWDTLTAGDRFAVAGDLVMSTLNPNYWGLIDNTYQRFATQKTKKMDYGMYCGAITVSSVNDELSQASVNNSDNAGLAASVAAEYDKGRFAAVARAQEILRPIMQQAAKTYFPTGGSGGGGQQNAFYFHEGSGYQNIPLQIKAAVAAYNQEMLNAAQKALQMGAPQQGGNSAGTNLSQVTNGLGWASAGLYYTTLARIQGVVYSRASYPPSFSPDIQTPEAISIDSQVLSKALYSNSESQPGTLADFRTWWGRNNRAFLLDNERAENAAMAGTSTLKTSLFGELSDGASWWLIDKLLEGFKINPFNAMLSLVELGHSILSWITALGATIGVVSMASLTPAGLMGSAVMGGAGKGGIIGSFFLGVGVMILGALFTAGIVLAYILPMIPYLIVTFFVMAMLILVAEAMVAAPLWAFFHVRMDGQEFVESVQRPGYMISFNLLLRPSLMILGLIMSYLIHGAMAWFVWQTFKIAAKGATAGFSVGPVGAVVFISMYAYINYMIAIRCFNLATQVPDRVARWFGGQGEHTDEERMTQQAAGAMSGQIAQRAGSTINAGTIAGALGGGQQGRFPGGTPGGPRGLGAPGGRGPQMGRLANLGDNMANRTAGGGQEESGYAGGGQAGGQAGGGGGEAYGAGGSSGGGSRGGPGEPATAMGRRFANAAQEAGRAIGAGRRERDASRGGDAGPQDRTASRSGAVGSAGMGSTYGGNGRGGERSGQTGGDRVRRDNADPGVQNASFTRRGQMENRHQDIDDD
>NC_012811.1|WP_043767695.1|624144_624561_-|hypothetical-protein
MFDTNTHTGIDQGVAVGLALAVGNRIRGQEIAHENDLLLAEQAHEADLARYQAVIDQLRGQLLNTQIDLAAERCEIAGLRAFIKEVRTLDPATPALGASDQLGRGGRAKSIAKVAYETAYDRQADEFGLPALKGTYAK
>NC_012811.1|WP_158022476.1|624922_625267_-|YkgJ-family-cysteine-cluster-protein
MSPAFSMDGPYDCQACGACCVAVGPVAVQPHDTQVPRRRTRSVRRMVGFASFEADLGVRCMKADDGRCGALVGQPGSRVACGIYDRRPSVCAEFQPGSGYCLEARASARARFSA
>NC_012811.1|WP_043767699.1|625565_626408_-|GIY-YIG-nuclease-family-protein
METGVLFIGSQSDCKAFIRKFECYYIYILRRPDGRPFYIGKGRGERVFHHENEARHANNRKSNAYKLNVIRAVLSAGGTISYEIDSFHEHEAAAHEREMQLIRAIGRLHEGGPLTNLAPGGGSERGASPSSKLRHSATLSGAPADNPERAAINTFVTGIAPMNSVVIKPASQFIAKATQQYPSKTMKPSLRQAVALAASAASNGILLEGECMIPRKVVIDDVDGLIENGVSCDIVTSNLGFLVAAETPSEECFRLSAQQTKIVIALLGAQKCIDLGILRP
>NC_012811.1|WP_158022501.1|626539_628345_-|hypothetical-protein
MAHVSEVESGGRCACVCPGCGAPLVAKKGARIDHHFAHEGTADGMPCRTGPETALHKFAKEVLARRLHLELPPLTLEEGGDRWIGYGGGRYRFDGAVLEQRLGGIVPDVIVRRGDRDLLVEMAVTHPCGPEKIETIRSLDVAAIEIDLAGLPRDVSRADLEASILEAAPRRWIHNPHLADGRAELERRRALRQASARQRAQALAATYAKAMQELGAIRPSSKVLGEMTRDGFGTSIGIQVSGAGCFTVPPGDWQAELLSGMWDAYQARQTTTFTAERALARLRKQGWVRPQFARMSDQEVAGAKQEQVGFGSPLDAIRHWAAAVTFSGILMPWRPGWRVQGGYLLRASEARGRRLLPARRASEIKGLVGQILSCLPEAERDGFDLKAWAAAPLPGCGHSAAEATRFDDAKYEAFKATLTRLASDARYGSHLDHDHLGLPLEGLAARKQAAARAKSEAIRQERIAREEAATRARGEELLADARSELGSDADGWAATPRSELGGISPVDAARSSPAGARAAHGAVREEVRRVGVLAAGAAEAEEARRLLRVEARKLVPPAQFDLYLKSRRPELGGKSPLEFCVSPGFVPRCIAATLPSSRNRR
>NC_012811.1|WP_012753964.1|628617_629085_+|hypothetical-protein
MKASSRTMLATCLAVLASCGSPFAQTLPAPVQKSMQEARKSCKPEKAVFGKDFVARKDVNGDGVPDYVLDYEHFECGGSSSYYCGTGGCLTQVFASNDGGYVKVLDENVQGLEFKTLKGRPAMQIGLHGSSCGRPGMDPCGATLYWNGAKFSPAN
>NC_012811.1|WP_012753965.1|629202_630330_-|transposase
MSDATQVRSYKYRLRPNAAQSAALDAMLRDFCGLHNACLQQRDEAWRRRRKRLRYADQAAELRGARAEEPTLARWSFTALQQVLRRVEQSYAAFLSGKRGRPRFRAAARYHAATFRVGDGLRLRPNGRITVLGVPGEIKAVWHRTLPADARLGTAILTRQSGKWHVVLSVEATFAAPDGAGDVGVDLGLTCLFATSDGHREPIPRFERRAHKAQRRRQRALARCKRGSRRRAKAKLRLAAASARIARQRRDHAHKLSHGLVAAYRRLAFEDLNTAGLKRSRLARSIHDAAWRQLVEMCRYKASSAGGEVHLVDPRGTSQMCPVCGAVAAKPLSLRRHACACGCELDRDVAAAQVIRDRAFGPGHGLRSISGRVAA
>NC_012811.1|WP_012753966.1|630380_631349_-|hypothetical-protein
MPRVIDFTQGNETDWNEVRLPAPVLGTREISDEEIEAIADAMKDLVHGFEPQFSTYGRSVPRDQAAELYDAAHAWLSENATGPWHWTEHWSNHGHNIDVAVYVERVPDQAAFAAAFEHLFRYTPASEHALQKLAIERGVLPPLTSKESFLKWTREHQGFEFLPYEDLGDKGIRIAFSHPEIEAKFVERYGAKFTIEESDGRRTYAGSTAGTTWRDSPDTWLSNQSAIGNMRSSRDGAWELEVRYANVAEALVRDWGHIFQPGGDEGTYRAAEYPGVPYRVLPSDFRAYLEGTSDSYDAPYLPDELRRLLPQRIPSFRPGVSA
>NC_012811.1|WP_012753967.1|631417_632608_-|hypothetical-protein
MTSSPSMRRHGRRQFKPFRLSGSGPSPHEWIDSYGFRNRLVTPDDFPDRRWSSRFADAVLDLLPSNRREKMAAVLFAVACAVGAVLLLLPWDDGGRSRALLSADEFALSRMPPVVHAPPPPLSAPLISVPSVPADGIRPPPVVDLSAPGESRRFCPPGSAFGTAYDPSPCMPAPPIEGRKVYELRLAGNHQVGFLGALGARLGIPTGSLSLKVDGEQDPRDVALGQTTVGEAGKAVPAAPIASRLFVSIAMTVVAIVISFCLGSVAAHVLGSVVESWTGIPNPELKRSVASLACAGTLLVLGMFLMRNRPDADAWEMLPLLLGSMAMLWRPERLPNQFGALTAVLACIMITQVPLVPPHSALASLYGPAGLYVWDFVYLGLIAVVGHQCWRRITIT
>NC_012811.1|WP_012753969.1|633318_634200_+|porin
MKKLLLLSAILATSTTAALAADLPLRGAPPEPAPAVATPVFTWTGFFAGFNAGYGFGTSDDRGPITAAVPGTYGVFSNPGPQVIAFAGQRSADGFVGGGQIGYNYQFTPGSGVVVGVEADAQYVDFGSDRNRFVATSPLAPGAVAFNPNTLTGLDYFGTVRGRLGYAFDRTLVYATGGFAYGSGGGRDFGLPNFTRDEFQTGWTVGGGVEYALPTDSFLNFFRSSAVTLRVEGLYVNLDQGNRNNGLFAVGATGIPVGLGSAGVVQVSGSGNNRVDTEFAVIRSGVNYKFGSY

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NC_012811_1	1.1\|577843\|43\|NC_012811\|CRT	577843-577885	43	NC_012811	Methylorubrum extorquens AM1 megaplasmid, complete sequence	577843-577885	0	1.0
NC_012811_1	1.2\|577904\|41\|NC_012811\|CRT	577904-577944	41	NC_012811	Methylorubrum extorquens AM1 megaplasmid, complete sequence	577904-577944	0	1.0
NC_012811_1	1.3\|577963\|43\|NC_012811\|CRT	577963-578005	43	NC_012811	Methylorubrum extorquens AM1 megaplasmid, complete sequence	577963-578005	0	1.0
NC_012811_1	1.4\|578024\|45\|NC_012811\|CRT	578024-578068	45	NC_012811	Methylorubrum extorquens AM1 megaplasmid, complete sequence	578024-578068	0	1.0
NC_012811_1	1.5\|578087\|41\|NC_012811\|CRT	578087-578127	41	NC_012811	Methylorubrum extorquens AM1 megaplasmid, complete sequence	578087-578127	0	1.0
NC_012811_1	1.6\|578146\|43\|NC_012811\|CRT	578146-578188	43	NC_012811	Methylorubrum extorquens AM1 megaplasmid, complete sequence	578146-578188	0	1.0
NC_012811_1	1.7\|578207\|39\|NC_012811\|CRT	578207-578245	39	NC_012811	Methylorubrum extorquens AM1 megaplasmid, complete sequence	578207-578245	0	1.0
NC_012811_1	1.8\|578264\|43\|NC_012811\|CRT	578264-578306	43	NC_012811	Methylorubrum extorquens AM1 megaplasmid, complete sequence	578264-578306	0	1.0
NC_012811_1	1.9\|577977\|30\|NC_012811\|CRISPRCasFinder	577977-578006	30	NC_012811	Methylorubrum extorquens AM1 megaplasmid, complete sequence	577977-578006	0	1.0
NC_012811_1	1.10\|578278\|30\|NC_012811\|CRISPRCasFinder	578278-578307	30	NC_012811	Methylorubrum extorquens AM1 megaplasmid, complete sequence	578278-578307	0	1.0
NC_012811_2	2.1\|620410\|35\|NC_012811\|CRISPRCasFinder	620410-620444	35	NC_012811	Methylorubrum extorquens AM1 megaplasmid, complete sequence	620410-620444	0	1.0
NC_012811_1	1.9\|577977\|30\|NC_012811\|CRISPRCasFinder	577977-578006	30	NC_010514	Methylobacterium radiotolerans JCM 2831 plasmid pMRAD03, complete sequence	10507-10536	1	0.967
NC_012811_1	1.9\|577977\|30\|NC_012811\|CRISPRCasFinder	577977-578006	30	NC_013858	Azospirillum sp. B510 plasmid pAB510d, complete sequence	483314-483343	4	0.867
NC_012811_1	1.9\|577977\|30\|NC_012811\|CRISPRCasFinder	577977-578006	30	NZ_CP024583	Roseomonas sp. FDAARGOS_362 plasmid unnamed2, complete sequence	184593-184622	6	0.8
NC_012811_1	1.9\|577977\|30\|NC_012811\|CRISPRCasFinder	577977-578006	30	NC_013857	Azospirillum sp. B510 plasmid pAB510c, complete sequence	376414-376443	7	0.767
NC_012811_1	1.9\|577977\|30\|NC_012811\|CRISPRCasFinder	577977-578006	30	NZ_CP050118	Deinococcus radiodurans strain BNK-50 plasmid pMP1, complete sequence	42653-42682	7	0.767
NC_012811_1	1.9\|577977\|30\|NC_012811\|CRISPRCasFinder	577977-578006	30	NZ_CP050122	Deinococcus radiodurans strain BND-54 plasmid pMP1, complete sequence	164504-164533	7	0.767
NC_012811_1	1.9\|577977\|30\|NC_012811\|CRISPRCasFinder	577977-578006	30	NC_000958	Deinococcus radiodurans R1 plasmid MP1, complete sequence	159288-159317	7	0.767
NC_012811_1	1.9\|577977\|30\|NC_012811\|CRISPRCasFinder	577977-578006	30	NZ_CP029232	Sinorhizobium fredii CCBAU 45436 plasmid pSF45436b, complete sequence	834230-834259	7	0.767
NC_012811_1	1.9\|577977\|30\|NC_012811\|CRISPRCasFinder	577977-578006	30	NZ_CP031502	Deinococcus radiodurans strain R1 dM1 plasmid pMP1, complete sequence	175073-175102	7	0.767
NC_012811_1	1.9\|577977\|30\|NC_012811\|CRISPRCasFinder	577977-578006	30	NZ_CP032326	Azospirillum brasilense strain MTCC4035 plasmid p5, complete sequence	14215-14244	7	0.767
NC_012811_1	1.9\|577977\|30\|NC_012811\|CRISPRCasFinder	577977-578006	30	NZ_CP014519	Sinomonas atrocyanea strain KCTC 3377 plasmid pSA01, complete sequence	36705-36734	7	0.767
NC_012811_1	1.9\|577977\|30\|NC_012811\|CRISPRCasFinder	577977-578006	30	NZ_CP029832	Azospirillum ramasamyi strain M2T2B2 plasmid unnamed2, complete sequence	319235-319264	8	0.733
NC_012811_1	1.9\|577977\|30\|NC_012811\|CRISPRCasFinder	577977-578006	30	NZ_CP029232	Sinorhizobium fredii CCBAU 45436 plasmid pSF45436b, complete sequence	1345366-1345395	8	0.733
NC_012811_1	1.9\|577977\|30\|NC_012811\|CRISPRCasFinder	577977-578006	30	NZ_CP029452	Sinorhizobium fredii CCBAU 25509 plasmid pSF25509b, complete sequence	770651-770680	8	0.733
NC_012811_1	1.9\|577977\|30\|NC_012811\|CRISPRCasFinder	577977-578006	30	NC_006569	Ruegeria pomeroyi DSS-3 megaplasmid, complete sequence	136867-136896	8	0.733
NC_012811_1	1.9\|577977\|30\|NC_012811\|CRISPRCasFinder	577977-578006	30	NZ_CP021357	Rhodococcus sp. S2-17 plasmid pRB11, complete sequence	8514-8543	8	0.733
NC_012811_1	1.9\|577977\|30\|NC_012811\|CRISPRCasFinder	577977-578006	30	NZ_CP023071	Sinorhizobium fredii CCBAU 83666 plasmid pSF83666b, complete sequence	730560-730589	8	0.733
NC_012811_1	1.9\|577977\|30\|NC_012811\|CRISPRCasFinder	577977-578006	30	NZ_CP023066	Sinorhizobium sp. CCBAU 05631 plasmid pSS05631d, complete sequence	7748-7777	8	0.733
NC_012811_1	1.9\|577977\|30\|NC_012811\|CRISPRCasFinder	577977-578006	30	NZ_CP004394	Celeribacter indicus strain P73 plasmid pP73A, complete sequence	64706-64735	8	0.733
NC_012811_1	1.9\|577977\|30\|NC_012811\|CRISPRCasFinder	577977-578006	30	NC_005793	Achromobacter denitrificans plasmid pEST4011, complete sequence	19363-19392	10	0.667
NC_012811_1	1.3\|577963\|43\|NC_012811\|CRT	577963-578005	43	NC_010514	Methylobacterium radiotolerans JCM 2831 plasmid pMRAD03, complete sequence	10493-10535	11	0.744

1. spacer 1.1|577843|43|NC_012811|CRT matches to NC_012811 (Methylorubrum extorquens AM1 megaplasmid, complete sequence) position: , mismatch: 0, identity: 1.0

cggggacgacagtccgacgcttcggatcccacgtagctgggga	CRISPR spacer
cggggacgacagtccgacgcttcggatcccacgtagctgggga	Protospacer
*******************************************

2. spacer 1.2|577904|41|NC_012811|CRT matches to NC_012811 (Methylorubrum extorquens AM1 megaplasmid, complete sequence) position: , mismatch: 0, identity: 1.0

gggaatataggagatcggcgtcgaccccgccgtgtgccgat	CRISPR spacer
gggaatataggagatcggcgtcgaccccgccgtgtgccgat	Protospacer
*****************************************

3. spacer 1.3|577963|43|NC_012811|CRT matches to NC_012811 (Methylorubrum extorquens AM1 megaplasmid, complete sequence) position: , mismatch: 0, identity: 1.0

cgcggaggagacagggcgaggttgggcaggatcaggccgccgg	CRISPR spacer
cgcggaggagacagggcgaggttgggcaggatcaggccgccgg	Protospacer
*******************************************

4. spacer 1.4|578024|45|NC_012811|CRT matches to NC_012811 (Methylorubrum extorquens AM1 megaplasmid, complete sequence) position: , mismatch: 0, identity: 1.0

cgcggaggagacagataacacccgtgctcaaacatcgcgagggag	CRISPR spacer
cgcggaggagacagataacacccgtgctcaaacatcgcgagggag	Protospacer
*********************************************

5. spacer 1.5|578087|41|NC_012811|CRT matches to NC_012811 (Methylorubrum extorquens AM1 megaplasmid, complete sequence) position: , mismatch: 0, identity: 1.0

gggaagacagagctgggtcaggctgacatccttggtgaaca	CRISPR spacer
gggaagacagagctgggtcaggctgacatccttggtgaaca	Protospacer
*****************************************

6. spacer 1.6|578146|43|NC_012811|CRT matches to NC_012811 (Methylorubrum extorquens AM1 megaplasmid, complete sequence) position: , mismatch: 0, identity: 1.0

cggggaggacagatggacggatgggcggagcgtatgatctcga	CRISPR spacer
cggggaggacagatggacggatgggcggagcgtatgatctcga	Protospacer
*******************************************

7. spacer 1.7|578207|39|NC_012811|CRT matches to NC_012811 (Methylorubrum extorquens AM1 megaplasmid, complete sequence) position: , mismatch: 0, identity: 1.0

gggaagaaaatggggcgctgccgcgctcgaactcgtcgc	CRISPR spacer
gggaagaaaatggggcgctgccgcgctcgaactcgtcgc	Protospacer
***************************************

8. spacer 1.8|578264|43|NC_012811|CRT matches to NC_012811 (Methylorubrum extorquens AM1 megaplasmid, complete sequence) position: , mismatch: 0, identity: 1.0

cgcgggggagagatcctgcagggtacgccgacagacgtccacg	CRISPR spacer
cgcgggggagagatcctgcagggtacgccgacagacgtccacg	Protospacer
*******************************************

9. spacer 1.9|577977|30|NC_012811|CRISPRCasFinder matches to NC_012811 (Methylorubrum extorquens AM1 megaplasmid, complete sequence) position: , mismatch: 0, identity: 1.0

ggcgaggttgggcaggatcaggccgccggt	CRISPR spacer
ggcgaggttgggcaggatcaggccgccggt	Protospacer
******************************

10. spacer 1.10|578278|30|NC_012811|CRISPRCasFinder matches to NC_012811 (Methylorubrum extorquens AM1 megaplasmid, complete sequence) position: , mismatch: 0, identity: 1.0

cctgcagggtacgccgacagacgtccacga	CRISPR spacer
cctgcagggtacgccgacagacgtccacga	Protospacer
******************************

11. spacer 2.1|620410|35|NC_012811|CRISPRCasFinder matches to NC_012811 (Methylorubrum extorquens AM1 megaplasmid, complete sequence) position: , mismatch: 0, identity: 1.0

ccggtgcgatcacgcagcgctacctcagcgacccc	CRISPR spacer
ccggtgcgatcacgcagcgctacctcagcgacccc	Protospacer
***********************************

12. spacer 1.9|577977|30|NC_012811|CRISPRCasFinder matches to NC_010514 (Methylobacterium radiotolerans JCM 2831 plasmid pMRAD03, complete sequence) position: , mismatch: 1, identity: 0.967

ggcgaggttgggcaggatcaggccgccggt	CRISPR spacer
ggcgaggttgggcaggatcaagccgccggt	Protospacer
********************.*********

13. spacer 1.9|577977|30|NC_012811|CRISPRCasFinder matches to NC_013858 (Azospirillum sp. B510 plasmid pAB510d, complete sequence) position: , mismatch: 4, identity: 0.867

ggcgaggttgggcaggatcaggcc--gccggt	CRISPR spacer
ggcgaggttgagcaggatctggccgagccg--	Protospacer
**********.******** ****  ****

14. spacer 1.9|577977|30|NC_012811|CRISPRCasFinder matches to NZ_CP024583 (Roseomonas sp. FDAARGOS_362 plasmid unnamed2, complete sequence) position: , mismatch: 6, identity: 0.8

ggcgaggttgggcaggatcaggccgccggt	CRISPR spacer
gtcggcattggccaggatcaggccgccggc	Protospacer
* **. .**** *****************.

15. spacer 1.9|577977|30|NC_012811|CRISPRCasFinder matches to NC_013857 (Azospirillum sp. B510 plasmid pAB510c, complete sequence) position: , mismatch: 7, identity: 0.767

ggcgaggttgggcaggatcaggccgccggt	CRISPR spacer
tacgaggtctggcaggatcaggccgccctc	Protospacer
 .******. *****************  .

16. spacer 1.9|577977|30|NC_012811|CRISPRCasFinder matches to NZ_CP050118 (Deinococcus radiodurans strain BNK-50 plasmid pMP1, complete sequence) position: , mismatch: 7, identity: 0.767

ggcgaggttgggcaggatcaggccgccggt	CRISPR spacer
ttcgaggttgggcagggtcaggcggcggcc	Protospacer
  **************.****** ** * .

17. spacer 1.9|577977|30|NC_012811|CRISPRCasFinder matches to NZ_CP050122 (Deinococcus radiodurans strain BND-54 plasmid pMP1, complete sequence) position: , mismatch: 7, identity: 0.767

ggcgaggttgggcaggatcaggccgccggt	CRISPR spacer
ttcgaggttgggcagggtcaggcggcggcc	Protospacer
  **************.****** ** * .

18. spacer 1.9|577977|30|NC_012811|CRISPRCasFinder matches to NC_000958 (Deinococcus radiodurans R1 plasmid MP1, complete sequence) position: , mismatch: 7, identity: 0.767

ggcgaggttgggcaggatcaggccgccggt	CRISPR spacer
ttcgaggttgggcagggtcaggcggcggcc	Protospacer
  **************.****** ** * .

19. spacer 1.9|577977|30|NC_012811|CRISPRCasFinder matches to NZ_CP029232 (Sinorhizobium fredii CCBAU 45436 plasmid pSF45436b, complete sequence) position: , mismatch: 7, identity: 0.767

ggcgaggttgggcaggatcaggccgccggt	CRISPR spacer
ggcgagggtggtcaggatcaggccactcac	Protospacer
******* *** ************.*. ..

20. spacer 1.9|577977|30|NC_012811|CRISPRCasFinder matches to NZ_CP031502 (Deinococcus radiodurans strain R1 dM1 plasmid pMP1, complete sequence) position: , mismatch: 7, identity: 0.767

ggcgaggttgggcaggatcaggccgccggt	CRISPR spacer
ttcgaggttgggcagggtcaggcggcggcc	Protospacer
  **************.****** ** * .

21. spacer 1.9|577977|30|NC_012811|CRISPRCasFinder matches to NZ_CP032326 (Azospirillum brasilense strain MTCC4035 plasmid p5, complete sequence) position: , mismatch: 7, identity: 0.767

ggcgaggttgggcaggatcaggccgccggt	CRISPR spacer
gaccccgttgagcaggatcaggccggcggc	Protospacer
*.*   ****.************** ***.

22. spacer 1.9|577977|30|NC_012811|CRISPRCasFinder matches to NZ_CP014519 (Sinomonas atrocyanea strain KCTC 3377 plasmid pSA01, complete sequence) position: , mismatch: 7, identity: 0.767

ggcgaggttgggcaggatcaggccgccggt	CRISPR spacer
cgcgagggtgggcaggatcagggtcccgtc	Protospacer
 ****** ************** . *** .

23. spacer 1.9|577977|30|NC_012811|CRISPRCasFinder matches to NZ_CP029832 (Azospirillum ramasamyi strain M2T2B2 plasmid unnamed2, complete sequence) position: , mismatch: 8, identity: 0.733

ggcgaggttgggcaggatcaggccgccggt	CRISPR spacer
tacgaggtttggcaggatcaggcggcactc	Protospacer
 .******* ************* **   .

24. spacer 1.9|577977|30|NC_012811|CRISPRCasFinder matches to NZ_CP029232 (Sinorhizobium fredii CCBAU 45436 plasmid pSF45436b, complete sequence) position: , mismatch: 8, identity: 0.733

ggcgaggttgggcaggatcaggccgccggt	CRISPR spacer
atggtcgttgggcaggatgaagccgccggc	Protospacer
.  *  ************ *.********.

25. spacer 1.9|577977|30|NC_012811|CRISPRCasFinder matches to NZ_CP029452 (Sinorhizobium fredii CCBAU 25509 plasmid pSF25509b, complete sequence) position: , mismatch: 8, identity: 0.733

ggcgaggttgggcaggatcaggccgccggt	CRISPR spacer
atggtcgttgggcaggatgaagccgccggc	Protospacer
.  *  ************ *.********.

26. spacer 1.9|577977|30|NC_012811|CRISPRCasFinder matches to NC_006569 (Ruegeria pomeroyi DSS-3 megaplasmid, complete sequence) position: , mismatch: 8, identity: 0.733

ggcgaggttgggcaggatcaggccgccggt	CRISPR spacer
aagcaggttcggcaggatcaggccggcatt	Protospacer
..  ***** *************** *. *

27. spacer 1.9|577977|30|NC_012811|CRISPRCasFinder matches to NZ_CP021357 (Rhodococcus sp. S2-17 plasmid pRB11, complete sequence) position: , mismatch: 8, identity: 0.733

ggcgaggttgggcaggatcaggccgccggt	CRISPR spacer
gatttcgttgagcaggaccaggccgccggc	Protospacer
*..   ****.******.***********.

28. spacer 1.9|577977|30|NC_012811|CRISPRCasFinder matches to NZ_CP023071 (Sinorhizobium fredii CCBAU 83666 plasmid pSF83666b, complete sequence) position: , mismatch: 8, identity: 0.733

ggcgaggttgggcaggatcaggccgccggt	CRISPR spacer
atggtcgttgggcaggatgaagccgccggc	Protospacer
.  *  ************ *.********.

29. spacer 1.9|577977|30|NC_012811|CRISPRCasFinder matches to NZ_CP023066 (Sinorhizobium sp. CCBAU 05631 plasmid pSS05631d, complete sequence) position: , mismatch: 8, identity: 0.733

ggcgaggttgggcaggatcaggccgccggt	CRISPR spacer
gccgaggttgcgcaggatcaggcgcttgaa	Protospacer
* ******** ************  ..*.

30. spacer 1.9|577977|30|NC_012811|CRISPRCasFinder matches to NZ_CP004394 (Celeribacter indicus strain P73 plasmid pP73A, complete sequence) position: , mismatch: 8, identity: 0.733

ggcgaggttgggcaggatcaggccgccggt	CRISPR spacer
gagatcgttggtctggatcaggccgccggg	Protospacer
*. .  ***** * ***************

31. spacer 1.9|577977|30|NC_012811|CRISPRCasFinder matches to NC_005793 (Achromobacter denitrificans plasmid pEST4011, complete sequence) position: , mismatch: 10, identity: 0.667

ggcgaggttgggcaggatcaggccgccggt	CRISPR spacer
cctccccttgggctggatcaggccgccgca	Protospacer
  .    ****** **************

32. spacer 1.3|577963|43|NC_012811|CRT matches to NC_010514 (Methylobacterium radiotolerans JCM 2831 plasmid pMRAD03, complete sequence) position: , mismatch: 11, identity: 0.744

cgcggaggagacagggcgaggttgggcaggatcaggccgccgg	CRISPR spacer
tcgggttccaggagggcgaggttgggcaggatcaagccgccgg	Protospacer
.  **    .. **********************.********

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

0 : 16652

Agrobacterium_phage(33.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_131473057.1\|953_2375_+	hypothetical protein	NA	NA	NA	NA
WP_003598529.1\|2553_3141_+	hypothetical protein	NA	NA	NA	NA
WP_003598530.1\|3161_3551_+	hypothetical protein	NA	NA	NA	NA
WP_003598531.1\|3819_4809_-	AraC family transcriptional regulator	NA	NA	NA	NA
WP_012753525.1\|4949_5534_+	DUF3280 domain-containing protein	NA	NA	NA	NA
WP_131473058.1\|5629_6088_-	helix-turn-helix transcriptional regulator	A0A223W054	Agrobacterium_phage	8.5e-13	36.8
WP_003598534.1\|7675_8416_+	SDR family oxidoreductase	NA	NA	NA	NA
WP_003598535.1\|8471_15308_+	SDR family NAD(P)-dependent oxidoreductase	D0R7J2	Paenibacillus_phage	3.9e-29	29.2
WP_003598536.1\|15359_16652_+	NAD(P)-binding domain-containing protein	A0A2H4J2Q2	uncultured_Caudovirales_phage	2.6e-11	27.0

DBSCAN-SWA_2

31060 : 34526

Mollivirus(33.33%)

transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_003598550.1\|31060_32884_+	cytochrome P450	A0A0M4JJK6	Mollivirus	4.6e-17	23.2
WP_082222836.1\|32926_33154_-	DNA cytosine methyltransferase	M1PSQ0	Streptococcus_phage	9.0e-08	55.1
WP_076611539.1\|33175_34526_+\|transposase	IS3-like element ISMex16 family transposase	Q6J1X2	Lactobacillus_phage	2.6e-09	25.5

DBSCAN-SWA_3

37875 : 38805

Pseudomonas_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_003602968.1\|37875_38805_+	transglycosylase SLT domain-containing protein	A0A1Y0T0A2	Pseudomonas_phage	4.4e-16	30.2

DBSCAN-SWA_4

66012 : 67449

Pseudomonas_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_012753557.1\|66012_67449_-	MBOAT family protein	A0A125RNP0	Pseudomonas_phage	4.0e-61	38.2

DBSCAN-SWA_5

70821 : 72173

Lactobacillus_phage(100.0%)

transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_076611539.1\|70821_72173_-\|transposase	IS3-like element ISMex16 family transposase	Q6J1X2	Lactobacillus_phage	2.6e-09	25.5

DBSCAN-SWA_6

84550 : 85450

Klosneuvirus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_012753572.1\|84550_85450_-	HRDC domain-containing protein	A0A1V0SJN9	Klosneuvirus	7.2e-08	35.6

DBSCAN-SWA_7

89377 : 96792

Leptospira_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_012753575.1\|89377_92524_+	CusA/CzcA family heavy metal efflux RND transporter	S5VL66	Leptospira_phage	1.0e-24	19.9
WP_003600349.1\|92557_92923_+	hypothetical protein	NA	NA	NA	NA
WP_012753576.1\|92945_93416_+	DUF305 domain-containing protein	NA	NA	NA	NA
WP_003600351.1\|93607_93940_+	four-helix bundle copper-binding protein	NA	NA	NA	NA
WP_003600352.1\|93963_94197_+	hypothetical protein	NA	NA	NA	NA
WP_012753577.1\|94362_96792_+	cadmium-translocating P-type ATPase	A0A218MNH6	uncultured_virus	1.0e-80	36.8

DBSCAN-SWA_8

112566 : 115731

Leptospira_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_003599845.1\|112566_115731_-	efflux RND transporter permease subunit	S5VTK5	Leptospira_phage	1.4e-50	22.4

DBSCAN-SWA_9

122258 : 122630

uncultured_virus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_003599860.1\|122258_122630_+	DUF305 domain-containing protein	A0A218MND9	uncultured_virus	2.8e-06	38.6

DBSCAN-SWA_10

133023 : 144257

uncultured_Caudovirales_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_012605982.1\|133023_133380_+	DUF2958 domain-containing protein	A0A1W6DX76	Sphingobium_phage	5.3e-31	61.5
WP_012605983.1\|133376_134168_+	hydroxypyruvate reductase	NA	NA	NA	NA
WP_012753597.1\|134207_135620_+	pyruvate kinase	NA	NA	NA	NA
WP_012605985.1\|136070_136283_+	hypothetical protein	NA	NA	NA	NA
WP_012605986.1\|136330_137077_-	arsenical resistance protein ArsH	A0A2H4J5V6	uncultured_Caudovirales_phage	1.3e-82	65.7
WP_003599807.1\|137127_137487_+	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_012605987.1\|137479_138007_+	arsenate reductase ArsC	A0A2H4J8A6	uncultured_Caudovirales_phage	2.0e-26	43.9
WP_012605988.1\|138006_138432_+	arsenate reductase (glutaredoxin)	A0A2H4J8T1	uncultured_Caudovirales_phage	6.0e-45	63.7
WP_012605990.1\|139497_140673_+	MFS transporter	NA	NA	NA	NA
WP_003600291.1\|140860_141133_+	hypothetical protein	NA	NA	NA	NA
WP_043767489.1\|141263_143048_+	S8 family serine peptidase	A0A127AWU5	Bacillus_phage	9.9e-17	33.8
WP_155773804.1\|143067_143208_+	hypothetical protein	NA	NA	NA	NA
WP_012605994.1\|143576_144257_-	sigma-70 family RNA polymerase sigma factor	A0A076YQ50	Rhizobium_phage	1.7e-09	28.7

DBSCAN-SWA_11

148423 : 267349

101

Leptospira_phage(18.52%)

transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_076611187.1\|148423_149228_+\|transposase	IS5-like element ISMex32 family transposase	A0A0M5M147	Mycobacterium_phage	6.0e-22	32.8
WP_012753603.1\|150285_151521_-	carbohydrate porin	NA	NA	NA	NA
WP_012605998.1\|152377_152956_+	hypothetical protein	NA	NA	NA	NA
WP_012753604.1\|152928_153327_+	hypothetical protein	NA	NA	NA	NA
WP_012606000.1\|154236_154971_+	response regulator transcription factor	W8CYM9	Bacillus_phage	2.5e-27	33.8
WP_012606001.1\|154967_156302_+	HAMP domain-containing protein	A0A1V0SGX0	Hokovirus	3.8e-05	33.7
WP_003596692.1\|156398_156653_+	hypothetical protein	NA	NA	NA	NA
WP_012606002.1\|157215_157407_+	hypothetical protein	NA	NA	NA	NA
WP_003596689.1\|157751_158123_+	hypothetical protein	NA	NA	NA	NA
WP_012606003.1\|158247_159612_+	efflux RND transporter periplasmic adaptor subunit	NA	NA	NA	NA
WP_012606004.1\|159623_162872_+	CusA/CzcA family heavy metal efflux RND transporter	S5VTK5	Leptospira_phage	1.3e-62	24.1
WP_003596683.1\|162877_163432_+	hypothetical protein	NA	NA	NA	NA
WP_012606005.1\|163477_164395_+	cation transporter	NA	NA	NA	NA
WP_012606006.1\|164407_164578_+	hypothetical protein	NA	NA	NA	NA
WP_003596676.1\|164900_165155_+	hypothetical protein	NA	NA	NA	NA
WP_003596674.1\|165393_165534_+	hypothetical protein	NA	NA	NA	NA
WP_003596672.1\|165530_167075_-	DUF2235 domain-containing protein	NA	NA	NA	NA
WP_012606007.1\|167277_168018_-	Abi family protein	NA	NA	NA	NA
WP_012606256.1\|169763_171041_+\|transposase	IS110-like element ISMex12 family transposase	A0A1S7J231	Thermus_phage	2.6e-11	35.4
WP_003598644.1\|172874_173165_+	hypothetical protein	NA	NA	NA	NA
WP_003598646.1\|173161_173716_+	hypothetical protein	NA	NA	NA	NA
WP_131473059.1\|174195_174621_-	hypothetical protein	NA	NA	NA	NA
WP_003598647.1\|174617_174971_-	hypothetical protein	NA	NA	NA	NA
WP_049832675.1\|175085_176009_-\|transposase	IS110-like element ISMex31 family transposase	NA	NA	NA	NA
WP_085985055.1\|177150_178111_+\|transposase	IS630-like element ISMex30 family transposase	A0A2P0VP61	Tetraselmis_virus	2.3e-07	23.4
WP_003598652.1\|178279_178447_-	hypothetical protein	NA	NA	NA	NA
WP_041357443.1\|178521_178734_-	hypothetical protein	NA	NA	NA	NA
WP_080515519.1\|179042_179270_-	cytochrome C biogenesis protein	NA	NA	NA	NA
WP_003598654.1\|179371_180445_-	murein L,D-transpeptidase	NA	NA	NA	NA
WP_012753610.1\|180533_181055_-	signal peptidase II	NA	NA	NA	NA
WP_003598656.1\|181051_183247_-	cadmium-translocating P-type ATPase	E4ZFI9	Streptococcus_phage	3.2e-118	38.7
WP_003598658.1\|183347_183749_+	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_003598660.1\|184425_186846_-	heavy metal translocating P-type ATPase	E4ZFI9	Streptococcus_phage	3.6e-70	32.6
WP_003598662.1\|186913_187396_-	DUF305 domain-containing protein	A0A218MND9	uncultured_virus	3.9e-08	44.0
WP_003598663.1\|187450_187783_-	four-helix bundle copper-binding protein	NA	NA	NA	NA
WP_003598665.1\|187962_188361_-	DUF305 domain-containing protein	A0A218MND9	uncultured_virus	1.4e-08	45.9
WP_003598666.1\|188387_188753_-	hypothetical protein	NA	NA	NA	NA
WP_003598668.1\|188772_191922_-	CusA/CzcA family heavy metal efflux RND transporter	S5VL66	Leptospira_phage	1.9e-23	20.0
WP_003598670.1\|191935_193675_-	efflux RND transporter periplasmic adaptor subunit	NA	NA	NA	NA
WP_012753612.1\|193760_194240_-	hypothetical protein	NA	NA	NA	NA
WP_003598673.1\|194331_194544_-	heavy-metal-associated domain-containing protein	NA	NA	NA	NA
WP_003598674.1\|194924_195665_+	NYN domain-containing protein	NA	NA	NA	NA
WP_003598675.1\|195678_196155_-	metal-binding protein	NA	NA	NA	NA
WP_003598676.1\|196174_199348_-	efflux RND transporter permease subunit	S5VTK5	Leptospira_phage	1.9e-42	21.7
WP_085985476.1\|199754_200937_+\|transposase	IS3-like element ISMex5 family transposase	S5WIU1	Leptospira_phage	7.3e-32	32.4
WP_003598681.1\|202054_202276_-	hypothetical protein	NA	NA	NA	NA
WP_173390153.1\|202541_202901_-	hypothetical protein	NA	NA	NA	NA
WP_003598686.1\|203662_204094_-	hypothetical protein	NA	NA	NA	NA
WP_009867550.1\|206317_207586_-\|transposase	IS256-like element ISMex3 family transposase	A0A2P1JQX9	Mycobacterium_phage	2.5e-91	45.7
WP_043767519.1\|208155_209199_+\|transposase	IS110-like element ISMex9 family transposase	A0A1S7J231	Thermus_phage	7.9e-06	36.3
WP_012753615.1\|211130_211493_+	hypothetical protein	NA	NA	NA	NA
WP_085985476.1\|211886_213070_-\|transposase	IS3-like element ISMex5 family transposase	S5WIU1	Leptospira_phage	7.3e-32	32.4
WP_082222865.1\|213163_213619_+	DUF2380 domain-containing protein	NA	NA	NA	NA
WP_043767525.1\|213775_214126_-	hypothetical protein	NA	NA	NA	NA
WP_082222842.1\|214157_214379_-	FAD/NAD(P)-binding protein	NA	NA	NA	NA
WP_012753618.1\|214296_215403_-	RecQ family ATP-dependent DNA helicase	K7YHB4	Megavirus	6.7e-56	39.1
WP_003598388.1\|215497_215635_-	hypothetical protein	NA	NA	NA	NA
WP_043767528.1\|215631_216582_-	hypothetical protein	NA	NA	NA	NA
WP_012753620.1\|217435_217948_-	hypothetical protein	NA	NA	NA	NA
WP_012753621.1\|218117_218522_-	dihydrofolate reductase	A0A076YIY6	Rhizobium_phage	4.7e-23	41.9
WP_043767544.1\|218574_221055_-	hypothetical protein	NA	NA	NA	NA
WP_012753623.1\|221173_222301_-\|transposase	transposase	A0A7E5	Microcystis_virus	8.2e-17	32.1
WP_012753624.1\|222613_223081_-	hypothetical protein	NA	NA	NA	NA
WP_012753625.1\|223329_224076_+	DCL family protein	NA	NA	NA	NA
WP_158022446.1\|224195_224624_-	hypothetical protein	NA	NA	NA	NA
WP_012753629.1\|224613_224988_-	hypothetical protein	NA	NA	NA	NA
WP_012753630.1\|224984_225845_-	hypothetical protein	NA	NA	NA	NA
WP_162094044.1\|226030_227050_+	single-stranded DNA-binding protein	NA	NA	NA	NA
WP_012753632.1\|227238_227544_+	helix-turn-helix transcriptional regulator	A0A0K1LLP9	Caulobacter_phage	1.6e-07	45.5
WP_012753633.1\|227540_228887_+	type II toxin-antitoxin system HipA family toxin	NA	NA	NA	NA
WP_012753634.1\|228984_229635_-	transglutaminase-like cysteine peptidase	NA	NA	NA	NA
WP_012753635.1\|229724_230231_-	hypothetical protein	NA	NA	NA	NA
WP_012753636.1\|230288_230606_-	hypothetical protein	NA	NA	NA	NA
WP_012753637.1\|230685_231033_-	hypothetical protein	NA	NA	NA	NA
WP_012753638.1\|231029_231302_-	hypothetical protein	NA	NA	NA	NA
WP_003596419.1\|231709_231970_+	hypothetical protein	NA	NA	NA	NA
WP_012753639.1\|232280_232691_+	hypothetical protein	B4UTT1	Rhizobium_phage	3.6e-47	73.6
WP_012753641.1\|232971_233328_-	hypothetical protein	NA	NA	NA	NA
WP_158022447.1\|235159_236812_+	hypothetical protein	NA	NA	NA	NA
WP_082222843.1\|236829_239886_+	RHS domain-containing protein	NA	NA	NA	NA
WP_050772715.1\|239888_240101_+	SPOR domain-containing protein	NA	NA	NA	NA
WP_012778812.1\|240727_241738_+\|transposase	IS110-like element ISMex29 family transposase	A0A1S7J231	Thermus_phage	9.9e-14	29.0
WP_162094041.1\|244411_244654_+\|transposase	transposase	NA	NA	NA	NA
WP_080577080.1\|246194_247586_+\|transposase	IS21-like element ISMex13 family transposase	U5N3F9	Enterobacteria_phage	1.1e-44	34.1
WP_043766344.1\|247582_248449_+	ATP-binding protein	U5N3V8	Enterobacteria_phage	1.3e-51	46.7
WP_043767556.1\|250538_250778_+	hypothetical protein	NA	NA	NA	NA
WP_158022449.1\|251089_251578_-	hypothetical protein	NA	NA	NA	NA
WP_012753645.1\|251574_252237_-	hypothetical protein	NA	NA	NA	NA
WP_043767558.1\|252233_253316_-	hypothetical protein	NA	NA	NA	NA
WP_043767561.1\|253306_253957_-	hypothetical protein	NA	NA	NA	NA
WP_158022450.1\|254338_254824_-	prepilin-type N-terminal cleavage/methylation domain-containing protein	NA	NA	NA	NA
WP_012753650.1\|254820_256056_-	type II secretion system F family protein	NA	NA	NA	NA
WP_012753651.1\|256075_257830_-	type II/IV secretion system protein	NA	NA	NA	NA
WP_012753652.1\|258171_260253_+	type II secretion system secretin GspD	R9TEZ5	Vibrio_phage	3.4e-16	30.5
WP_158022452.1\|260246_260909_-	hypothetical protein	NA	NA	NA	NA
WP_012753653.1\|260993_261482_-	type II secretion system major pseudopilin GspG	NA	NA	NA	NA
WP_158022453.1\|261526_262105_+	prepilin peptidase	NA	NA	NA	NA
WP_050772717.1\|262101_262464_-	nitroreductase family protein	NA	NA	NA	NA
WP_009867550.1\|263190_264459_+\|transposase	IS256-like element ISMex3 family transposase	A0A2P1JQX9	Mycobacterium_phage	2.5e-91	45.7
WP_012753654.1\|265091_265790_+	hypothetical protein	NA	NA	NA	NA
WP_085985477.1\|265870_267349_+	AAA family ATPase	G3MAX6	Bacillus_virus	2.1e-41	34.7

DBSCAN-SWA_12

270519 : 271116

Erythrobacter_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_012753660.1\|270519_271116_+	MucR family transcriptional regulator	A0A1P8VVG0	Erythrobacter_phage	2.2e-21	44.2

DBSCAN-SWA_13

275927 : 276617

Aeromonas_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_012753668.1\|275927_276617_-	hypothetical protein	A0A291LE90	Aeromonas_phage	3.5e-10	29.7

DBSCAN-SWA_14

289837 : 293290

Gordonia_phage(50.0%)

transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_003596478.1\|289837_290578_-	hypothetical protein	A0A166Y0E3	Gordonia_phage	1.4e-52	59.9
WP_003596480.1\|290681_291173_-	hypothetical protein	NA	NA	NA	NA
WP_043767593.1\|291571_291976_+	hypothetical protein	NA	NA	NA	NA
WP_043767595.1\|292060_293290_+\|transposase	transposase	I4AZI9	Saccharomonospora_phage	6.5e-60	37.0

DBSCAN-SWA_15

300929 : 301799

Lactococcus_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_043767602.1\|300929_301799_-	ATP-binding protein	A0A059NT77	Lactococcus_phage	1.8e-40	39.1

DBSCAN-SWA_16

305092 : 305902

Planktothrix_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_012753701.1\|305092_305902_+	phosphonate ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	1.4e-23	38.6

DBSCAN-SWA_17

309857 : 313291

uncultured_Caudovirales_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_012753707.1\|309857_310571_-	arsenical resistance protein ArsH	A0A2H4J5V6	uncultured_Caudovirales_phage	9.6e-80	64.5
WP_043767958.1\|310654_311014_+	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_012753709.1\|311006_311534_+	arsenate reductase ArsC	A0A2H4J8A6	uncultured_Caudovirales_phage	3.4e-26	43.2
WP_043767611.1\|311533_311959_+	arsenate reductase (glutaredoxin)	A0A2H4J8T1	uncultured_Caudovirales_phage	1.3e-47	66.4
WP_012753711.1\|311995_313291_+	arsenic transporter	A0A2H4J144	uncultured_Caudovirales_phage	8.8e-140	61.2

DBSCAN-SWA_18

318988 : 319858

Lactococcus_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_043767602.1\|318988_319858_-	ATP-binding protein	A0A059NT77	Lactococcus_phage	1.8e-40	39.1

DBSCAN-SWA_19

327810 : 330121

Escherichia_phage(100.0%)

transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_043767620.1\|327810_328605_-	ATP-binding protein	A0A2L1IVB6	Escherichia_phage	1.3e-29	34.1
WP_158022498.1\|328594_330121_-\|transposase	IS21-like element ISMex27 family transposase	A0A2L1IVA1	Escherichia_phage	2.5e-16	25.0

DBSCAN-SWA_20

337641 : 341476

Rhizobium_phage(66.67%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_012753728.1\|337641_338475_-	serine/threonine protein phosphatase	V9QL63	Rhizobium_phage	2.4e-34	38.7
WP_012753729.1\|338532_339315_-	serine/threonine protein phosphatase	V9QL63	Rhizobium_phage	3.1e-23	34.3
WP_012753730.1\|339475_341476_+	ATP-dependent helicase	A0A068EQC7	Bacillus_phage	1.0e-41	25.2

DBSCAN-SWA_21

349380 : 349989

Cedratvirus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_012753742.1\|349380_349989_+	alpha/beta hydrolase	A0A285PWG0	Cedratvirus	9.8e-09	31.8

DBSCAN-SWA_22

363038 : 371715

Enterobacteria_phage(33.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_012753748.1\|363038_363902_+	DNA/RNA non-specific endonuclease	H6X497	Enterobacteria_phage	3.9e-27	32.6
WP_003596938.1\|363895_364156_+	hypothetical protein	NA	NA	NA	NA
WP_043767632.1\|364372_365116_+	response regulator	NA	NA	NA	NA
WP_012753750.1\|365129_368801_+	PAS-domain containing protein	Q8QKV7	Ectocarpus_siliculosus_virus	7.7e-40	30.3
WP_012753751.1\|368802_371715_+	response regulator	A0A1V0SGX0	Hokovirus	1.4e-55	34.0

DBSCAN-SWA_23

392255 : 393353

Burkholderia_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_003596909.1\|392255_393353_+	acyltransferase	A9YX16	Burkholderia_phage	3.6e-33	32.5

DBSCAN-SWA_24

402976 : 403870

Mycobacterium_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_012753776.1\|402976_403870_-	hypothetical protein	A0A0B5A0F7	Mycobacterium_phage	8.8e-06	25.9

DBSCAN-SWA_25

420164 : 421064

Clostridium_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_012753789.1\|420164_421064_-	ImmA/IrrE family metallo-endopeptidase	A0A090D850	Clostridium_phage	3.6e-07	33.8

DBSCAN-SWA_26

426329 : 427441

Leptospira_phage(100.0%)

transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_085985459.1\|426329_427441_-\|transposase	IS3-like element ISMex1 family transposase	S5WIU1	Leptospira_phage	6.8e-48	40.7

DBSCAN-SWA_27

446102 : 452348

Pseudomonas_phage(33.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_012753810.1\|446102_450044_+	TraM recognition domain-containing protein	F8SJ76	Pseudomonas_phage	5.2e-66	38.8
WP_003606808.1\|450047_450761_+	hypothetical protein	A0A0A8ILE3	Aurantimonas_phage	3.5e-05	29.3
WP_012753811.1\|450899_451175_+	hypothetical protein	NA	NA	NA	NA
WP_012753812.1\|451194_451818_-	hypothetical protein	NA	NA	NA	NA
WP_003606811.1\|451874_452348_-	macro domain-containing protein	A0A088C3J1	Shewanella_sp._phage	1.0e-05	28.8

DBSCAN-SWA_28

462998 : 466660

Bacillus_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_043767655.1\|462998_464861_-	single-stranded-DNA-specific exonuclease RecJ	A7KV88	Bacillus_phage	1.9e-55	29.5
WP_012753820.1\|464866_466660_-	ATP-dependent helicase	A7KV33	Bacillus_phage	4.6e-54	28.2

DBSCAN-SWA_29

469841 : 473095

uncultured_Caudovirales_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_012753822.1\|469841_470414_-	3'-5' exonuclease	A0A2H4J7C9	uncultured_Caudovirales_phage	4.4e-19	38.6
WP_012753823.1\|470500_473095_-	AAA family ATPase	A0A1P8DII4	Virus_Rctr197k	5.1e-30	31.8

DBSCAN-SWA_30

476545 : 476815

Sinorhizobium_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_012753828.1\|476545_476815_-	DUF2312 domain-containing protein	Q8W6H2	Sinorhizobium_phage	1.3e-21	71.1

DBSCAN-SWA_31

485143 : 487446

Ochrobactrum_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_003602323.1\|485143_486169_-	plasmid partitioning protein RepB	A0A240F4U0	Ochrobactrum_phage	3.2e-36	35.5
WP_003602321.1\|486168_487446_-	plasmid partitioning protein RepA	A0A240F4U1	Ochrobactrum_phage	2.6e-104	50.0

DBSCAN-SWA_32

492946 : 493915

Erythrobacter_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_012753840.1\|492946_493915_-	MucR family transcriptional regulator	A0A1P8VVG0	Erythrobacter_phage	6.2e-05	41.9

DBSCAN-SWA_33

523471 : 540637

Bacillus_virus(33.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_043767668.1\|523471_524647_+	lytic transglycosylase domain-containing protein	K4NWI2	Pseudomonas_phage	3.6e-23	41.8
WP_043767975.1\|524933_525920_-	hypothetical protein	NA	NA	NA	NA
WP_131473065.1\|526155_526527_+	hypothetical protein	NA	NA	NA	NA
WP_158022468.1\|526541_527000_+	hypothetical protein	NA	NA	NA	NA
WP_012753872.1\|527090_528671_+	extensin family protein	M4SNJ8	Pseudoalteromonas_phage	3.8e-12	33.9
WP_012753873.1\|528675_529350_+	hypothetical protein	NA	NA	NA	NA
WP_012753874.1\|529464_531081_+	amidohydrolase family protein	NA	NA	NA	NA
WP_003599249.1\|531160_533845_-	DNA gyrase subunit A	G3M9Z5	Bacillus_virus	3.7e-84	30.3
WP_012753875.1\|533884_534415_-	polymer-forming cytoskeletal protein	NA	NA	NA	NA
WP_012753876.1\|534558_535713_+	DNA cytosine methyltransferase	A0A1P8DJM9	Virus_Rctr41k	2.4e-24	32.9
WP_012753877.1\|535720_536566_-	hypothetical protein	NA	NA	NA	NA
WP_114415986.1\|536740_539206_-	DNA gyrase subunit B	G3M9Z3	Bacillus_virus	4.7e-09	47.0
WP_012753879.1\|539351_539807_+	hypothetical protein	NA	NA	NA	NA
WP_012753880.1\|539812_540637_-	J domain-containing protein	A0A2L0UZR4	Agrobacterium_phage	7.1e-10	22.5

DBSCAN-SWA_34

544340 : 546554

Bacillus_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_043767976.1\|544340_546554_+	ATP-dependent RecD-like DNA helicase	A0A218KCE8	Bacillus_phage	1.9e-57	29.9

DBSCAN-SWA_35

553824 : 554586

Vibrio_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_012753891.1\|553824_554586_-	sigma-70 family RNA polymerase sigma factor	A0A2I7RW72	Vibrio_phage	1.7e-05	27.7

DBSCAN-SWA_36

558329 : 559502

Yersinia_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_012753895.1\|558329_559502_+	hypothetical protein	G4KKC9	Yersinia_phage	6.7e-62	37.5

DBSCAN-SWA_37

564268 : 565081

Caulobacter_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_012753899.1\|564268_565081_-	metallophosphoesterase	K4K650	Caulobacter_phage	2.2e-40	34.6

DBSCAN-SWA_38

568674 : 569352

Streptococcus_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_012753905.1\|568674_569352_-	dTMP kinase	M1PSC7	Streptococcus_phage	2.3e-30	40.7

DBSCAN-SWA_39

586010 : 587219

Aeromonas_phage(100.0%)

transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_162094049.1\|586010_587219_-\|transposase	transposase	A0A1I9KF42	Aeromonas_phage	2.3e-17	27.2

DBSCAN-SWA_40

591212 : 591545

Ralstonia_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_012753927.1\|591212_591545_+	hypothetical protein	B2ZYH3	Ralstonia_phage	7.5e-19	51.6

DBSCAN-SWA_41

599629 : 602249

Cronobacter_phage(33.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_012753939.1\|599629_600958_-	Y-family DNA polymerase	F1C5A5	Cronobacter_phage	2.5e-89	43.4
WP_012753940.1\|600970_601405_-	translesion error-prone DNA polymerase V autoproteolytic subunit	A0A1W6JNS2	Morganella_phage	8.3e-18	40.0
WP_012753941.1\|601757_602249_+	MucR family transcriptional regulator	A0A1P8VVG0	Erythrobacter_phage	2.6e-20	45.3

DBSCAN-SWA_42

606456 : 612552

Rhodococcus_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_012753949.1\|606456_612552_+	putative Ig domain-containing protein	G9FH37	Rhodococcus_phage	7.1e-06	48.2

DBSCAN-SWA_43

629202 : 630330

Microcystis_virus(100.0%)

transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_012753965.1\|629202_630330_-\|transposase	transposase	A0A7E5	Microcystis_virus	1.4e-16	31.3

DBSCAN-SWA_44

639881 : 643100

Ectocarpus_siliculosus_virus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_012753975.1\|639881_643100_-	PAS domain S-box protein	Q8QKV7	Ectocarpus_siliculosus_virus	1.6e-44	34.5

DBSCAN-SWA_45

646864 : 648216

Lactobacillus_phage(100.0%)

transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_076611865.1\|646864_648216_-\|transposase	IS3-like element ISMex37 family transposase	Q6J1X2	Lactobacillus_phage	4.3e-12	29.1

DBSCAN-SWA_46

652198 : 654504

Aeromonas_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_003599000.1\|652198_652936_-	LuxR family transcriptional regulator	A0A1I9KF49	Aeromonas_phage	2.4e-17	28.6
WP_003599002.1\|653120_653687_-	hypothetical protein	NA	NA	NA	NA
WP_003599004.1\|653808_654504_-	response regulator transcription factor	A0A0K0PVG9	Roseobacter_phage	2.1e-15	50.0

DBSCAN-SWA_47

674955 : 684862

Bradyrhizobium_phage(25.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_012754009.1\|674955_675702_-	DNA polymerase III subunit epsilon	A0A1X9SH08	Bradyrhizobium_phage	3.7e-34	39.9
WP_012754010.1\|675771_676164_+	hypothetical protein	NA	NA	NA	NA
WP_003602949.1\|676181_676859_+	RusA family crossover junction endodeoxyribonuclease	NA	NA	NA	NA
WP_012754011.1\|676855_677359_+	L,D-transpeptidase	NA	NA	NA	NA
WP_012754012.1\|677392_678070_-	hypothetical protein	K4JRG5	Caulobacter_phage	6.0e-15	35.9
WP_012754013.1\|678098_678557_-	hypothetical protein	NA	NA	NA	NA
WP_012754014.1\|678622_680746_-	ATP-dependent helicase	A7KV33	Bacillus_phage	2.7e-53	26.7
WP_012754015.1\|680911_684862_+	DNA polymerase III subunit alpha	A0A0K1Y8F0	Streptomyces_phage	1.9e-153	33.8

DBSCAN-SWA_48

695657 : 704538

Streptococcus_phage(33.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_012754023.1\|695657_698324_-	DNA topoisomerase 3	A0A1X9I6W8	Streptococcus_phage	1.4e-35	32.5
WP_012754024.1\|698385_699225_-	hypothetical protein	Q4ZC36	Staphylococcus_virus	7.0e-05	30.6
WP_003604289.1\|699396_699774_+	hypothetical protein	NA	NA	NA	NA
WP_012754025.1\|699793_700822_-	hypothetical protein	NA	NA	NA	NA
WP_043767992.1\|700863_704538_-	strawberry notch C-terminal domain-containing protein	A0A0K0VLL6	Metopaulias_depressus_WSSV-like_virus	6.2e-05	26.6

DBSCAN-SWA_49

726619 : 734898

Mycobacterium_phage(50.0%)

integrase

attL 729296:729311|attR 737939:737954

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_012754047.1\|726619_726991_+	hypothetical protein	A0A1V0ED00	Caulobacter_phage	3.5e-09	31.5
WP_050772725.1\|726995_728447_+	DNA cytosine methyltransferase	A0A2H4PAK4	Aphanizomenon_phage	2.3e-19	32.7
WP_012754049.1\|728462_729263_+	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_012754050.1\|729275_729812_-	hypothetical protein	NA	NA	NA	NA
729296:729311	attL	NA	NA	NA	NA
WP_012754051.1\|729934_730735_+	peptidylprolyl isomerase	NA	NA	NA	NA
WP_193373953.1\|731085_731754_+	DNA cytosine methyltransferase	A0A076YHF8	Mycobacterium_phage	1.0e-11	48.5
WP_012754053.1\|731955_733068_-	hypothetical protein	NA	NA	NA	NA
WP_012754054.1\|733239_733713_+	hypothetical protein	NA	NA	NA	NA
WP_043767738.1\|733926_734898_-\|integrase	tyrosine-type recombinase/integrase	M4W8M4	Mycobacterium_phage	1.8e-12	28.6
737939:737954	attR	NA	NA	NA	NA

DBSCAN-SWA_50

742491 : 754391

Corynebacterium_phage(25.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_158022481.1\|742491_750987_+	putative Ig domain-containing protein	A0A1W6JQC9	Corynebacterium_phage	2.2e-05	40.0
WP_043767751.1\|751272_751680_+	septal ring lytic transglycosylase RlpA family protein	A0A0F6SJ38	Sinorhizobium_phage	8.3e-20	56.0
WP_012754067.1\|751684_752083_-	hypothetical protein	NA	NA	NA	NA
WP_012754068.1\|752158_752611_+	DNA mismatch endonuclease Vsr	I6NSG0	Burkholderia_phage	1.7e-34	55.2
WP_012754069.1\|752670_752919_+	hypothetical protein	NA	NA	NA	NA
WP_012754070.1\|752997_753810_+	hypothetical protein	NA	NA	NA	NA
WP_012754071.1\|753806_754391_+	metallophosphoesterase	A0A2H5BGP7	Vibrio_virus	1.3e-21	38.2

DBSCAN-SWA_51

806954 : 810495

Caulobacter_phage(33.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_043768021.1\|806954_807491_+	DUF262 domain-containing protein	K4JUV4	Caulobacter_phage	1.7e-36	53.4
WP_012754120.1\|807498_808488_+	hypothetical protein	NA	NA	NA	NA
WP_012754121.1\|808625_809852_+	DNA polymerase IV	I6RSM4	Salmonella_phage	6.8e-17	29.8
WP_012754122.1\|809973_810495_+	GIY-YIG nuclease family protein	A0A0M4U442	Ralstonia_phage	9.7e-05	34.1

DBSCAN-SWA_52

820802 : 892007

Leptospira_phage(13.64%)

transposase,protease,bacteriocin

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_012754133.1\|820802_821786_+	ATP-binding protein	A0A0U3CC34	Pseudomonas_phage	1.1e-14	29.4
WP_162094051.1\|822040_823411_+	S8 family serine peptidase	NA	NA	NA	NA
WP_043767785.1\|824385_825429_+\|transposase	IS110-like element ISMex9 family transposase	A0A1S7J231	Thermus_phage	7.9e-06	36.3
WP_012754134.1\|826041_826338_+	Twin-arginine translocation pathway signal precursor (fragment)	NA	NA	NA	NA
WP_012754135.1\|826371_827373_+	aldo/keto reductase	NA	NA	NA	NA
WP_012754136.1\|827435_828281_+	aldo/keto reductase	A0A2H4PQR8	Staphylococcus_phage	5.0e-51	42.1
WP_012754137.1\|828417_828975_+	NAD(P)H-dependent oxidoreductase	A0A2P0ZL77	Lactobacillus_phage	1.7e-15	35.1
WP_082222855.1\|829043_829727_-	CHAD domain-containing protein	NA	NA	NA	NA
WP_003596034.1\|829801_831451_+\|transposase	ISL3-like element ISMex10 family transposase	NA	NA	NA	NA
WP_043766344.1\|833478_834345_-	ATP-binding protein	U5N3V8	Enterobacteria_phage	1.3e-51	46.7
WP_080577080.1\|834341_835733_-\|transposase	IS21-like element ISMex13 family transposase	U5N3F9	Enterobacteria_phage	1.1e-44	34.1
WP_085985478.1\|836804_837903_+\|transposase	IS3-like element ISMex11 family transposase	S5WIU1	Leptospira_phage	4.1e-53	43.2
WP_012754139.1\|838466_839075_+	hypothetical protein	NA	NA	NA	NA
WP_012754140.1\|839183_840482_+	cytochrome c	NA	NA	NA	NA
WP_012754141.1\|840515_840977_+	(2Fe-2S)-binding protein	A0A0P0IVM8	Acinetobacter_phage	8.5e-13	38.5
WP_158022503.1\|840981_843282_+	molybdopterin-dependent oxidoreductase	NA	NA	NA	NA
WP_012754143.1\|843567_844389_-\|bacteriocin	bacteriocin family protein	NA	NA	NA	NA
WP_012754144.1\|844381_845458_-	Dyp-type peroxidase	NA	NA	NA	NA
WP_193373954.1\|845711_845966_-	DUF2171 domain-containing protein	NA	NA	NA	NA
WP_012754146.1\|846068_848684_-	ATP-dependent chaperone ClpB	A0A2I7SAX5	Vibrio_phage	2.6e-122	36.2
WP_043767798.1\|848877_849141_-	MerR family transcriptional regulator	NA	NA	NA	NA
WP_012754148.1\|849143_850046_-	J domain-containing protein	A0A2L0UZR4	Agrobacterium_phage	5.0e-25	29.3
WP_043767800.1\|850268_852173_-	molecular chaperone DnaK	G8DDB7	Micromonas_pusilla_virus	3.1e-149	49.2
WP_082222856.1\|852328_852985_-	nucleotide exchange factor GrpE	NA	NA	NA	NA
WP_085985476.1\|855362_856546_-\|transposase	IS3-like element ISMex5 family transposase	S5WIU1	Leptospira_phage	7.3e-32	32.4
WP_158022504.1\|856560_857886_+	sigma 54-interacting transcriptional regulator	NA	NA	NA	NA
WP_162094043.1\|857957_858110_-	hypothetical protein	NA	NA	NA	NA
WP_085985479.1\|858175_859314_-\|transposase	IS3-like element ISMex7 family transposase	A0A2P1JR32	Mycobacterium_phage	2.0e-18	30.1
WP_043768053.1\|859901_860393_-	phosphate-starvation-inducible PsiE family protein	NA	NA	NA	NA
WP_012754152.1\|860507_860999_-	Hsp20/alpha crystallin family protein	NA	NA	NA	NA
WP_012754153.1\|861019_861418_-	Hsp20/alpha crystallin family protein	A0A1B2LRT2	Wolbachia_phage	5.1e-06	29.8
WP_012754154.1\|861432_861858_-	Hsp20/alpha crystallin family protein	NA	NA	NA	NA
WP_012754155.1\|862060_862492_+	MarR family transcriptional regulator	NA	NA	NA	NA
WP_012754156.1\|862506_864339_+\|protease	ATP-dependent zinc metalloprotease FtsH	A0A0P0CCN8	Ostreococcus_mediterraneus_virus	3.4e-105	42.8
WP_012754157.1\|864401_867296_+\|protease	ATP-dependent Clp protease ATP-binding subunit	K4FB40	Cronobacter_phage	1.2e-123	39.9
WP_012754158.1\|867373_868546_+	sigma-70 family RNA polymerase sigma factor	NA	NA	NA	NA
WP_043767813.1\|868542_869190_+	HdeD family acid-resistance protein	NA	NA	NA	NA
WP_012754161.1\|869401_870022_+	hypothetical protein	NA	NA	NA	NA
WP_012754162.1\|870023_870587_+	ETC complex I subunit	NA	NA	NA	NA
WP_012754163.1\|871470_872385_+	heat resistance protein YfdX1	NA	NA	NA	NA
WP_012754164.1\|872487_873375_+	heat resistance protein YfdX2	NA	NA	NA	NA
WP_085985478.1\|873526_874625_+\|transposase	IS3-like element ISMex11 family transposase	S5WIU1	Leptospira_phage	4.1e-53	43.2
WP_012754165.1\|875465_875867_+	type IV secretory system conjugative DNA transfer family protein	NA	NA	NA	NA
WP_012754166.1\|876178_876475_-	hypothetical protein	NA	NA	NA	NA
WP_012754167.1\|876511_877135_-	AAA family ATPase	A2I303	Vibrio_virus	1.3e-19	37.6
WP_012754168.1\|877202_877508_-	type II toxin-antitoxin system RelE/ParE family toxin	NA	NA	NA	NA
WP_012754169.1\|877507_877774_-	CopG family ribbon-helix-helix protein	NA	NA	NA	NA
WP_003596034.1\|879428_881078_-\|transposase	ISL3-like element ISMex10 family transposase	NA	NA	NA	NA
WP_009867550.1\|881319_882588_-\|transposase	IS256-like element ISMex3 family transposase	A0A2P1JQX9	Mycobacterium_phage	2.5e-91	45.7
WP_158022486.1\|883935_884388_-	hypothetical protein	NA	NA	NA	NA
WP_012754171.1\|884469_885309_-	aldo/keto reductase	NA	NA	NA	NA
WP_012754172.1\|885512_886682_-	glutathione-dependent formaldehyde dehydrogenase	A0A0K0KVL7	Prochlorococcus_phage	6.5e-09	28.1
WP_012754173.1\|886694_887402_-	SRPBCC family protein	NA	NA	NA	NA
WP_012754174.1\|887991_888432_-	thioredoxin TrxC	A0A023NHA9	Dinoroseobacter_phage	2.5e-14	35.6
WP_012754175.1\|888781_889408_-	HdeD family acid-resistance protein	NA	NA	NA	NA
WP_043767605.1\|889641_891141_+\|transposase	IS21-like element ISMex8 family transposase	NA	NA	NA	NA
WP_043767602.1\|891137_892007_+	ATP-binding protein	A0A059NT77	Lactococcus_phage	1.8e-40	39.1

DBSCAN-SWA_53

903148 : 908885

Bacillus_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_162094052.1\|903148_905272_+	flap endonuclease	U5PWU8	Bacillus_phage	1.5e-16	30.9
WP_158022489.1\|905579_906128_+	hypothetical protein	NA	NA	NA	NA
WP_012754186.1\|906134_907220_-	hypothetical protein	NA	NA	NA	NA
WP_012754187.1\|907337_908885_-	DNA primase	A0A0K1LMQ9	Caulobacter_phage	2.6e-90	42.6

DBSCAN-SWA_54

913401 : 918139

Bacillus_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_012754196.1\|913401_916275_+	DNA polymerase I	B6V2J7	Bacillus_phage	1.2e-43	34.2
WP_003597064.1\|916274_916529_+	hypothetical protein	NA	NA	NA	NA
WP_012754197.1\|916518_916773_+	hypothetical protein	NA	NA	NA	NA
WP_012754198.1\|916769_917363_+	hypothetical protein	NA	NA	NA	NA
WP_012754199.1\|917422_918139_+	DUF2786 domain-containing protein	A0A219VHD3	Ochrobactrum_phage	1.2e-08	28.4

DBSCAN-SWA_55

922395 : 924081

Clostridioides_phage(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_003597049.1\|922395_923148_+	NERD domain-containing protein	A0A2R2ZH57	Clostridioides_phage	4.0e-12	32.8
WP_003597048.1\|923210_923576_+	hypothetical protein	NA	NA	NA	NA
WP_003597046.1\|923634_924081_+	NUDIX hydrolase	S5VM37	Pseudomonas_phage	1.2e-08	31.9

DBSCAN-SWA_56

928121 : 935235

Ectocarpus_siliculosus_virus(33.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_003597039.1\|928121_930260_+	hybrid sensor histidine kinase/response regulator	Q8QKY1	Ectocarpus_siliculosus_virus	3.2e-06	26.5
WP_003597038.1\|930256_932395_-	NAD-dependent DNA ligase LigA	A0A1W6DX16	Sphingobium_phage	4.4e-120	40.2
WP_012754209.1\|932507_933002_-	hypothetical protein	NA	NA	NA	NA
WP_003597034.1\|933191_934088_+	hypothetical protein	NA	NA	NA	NA
WP_003597030.1\|934200_935235_+	Holliday junction branch migration DNA helicase RuvB	B3GAM6	uncultured_virus	3.0e-05	33.3

DBSCAN-SWA_57

959724 : 972299

Leptospira_phage(40.0%)

transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_003597898.1\|959724_962862_+	efflux RND transporter permease subunit	S5VTK5	Leptospira_phage	1.1e-55	22.1
WP_003597899.1\|962980_963124_+	hypothetical protein	NA	NA	NA	NA
WP_003597900.1\|963245_963947_-	sigma-70 family RNA polymerase sigma factor	A0A076YQ50	Rhizobium_phage	1.0e-09	32.7
WP_003596034.1\|964054_965704_+\|transposase	ISL3-like element ISMex10 family transposase	NA	NA	NA	NA
WP_085985480.1\|965780_966963_+\|transposase	IS3-like element ISMex5 family transposase	S5WIU1	Leptospira_phage	7.3e-32	32.4
WP_158022491.1\|967022_967322_+	hypothetical protein	NA	NA	NA	NA
WP_082222861.1\|968010_970023_+	recombinase family protein	K4ICM1	Acidithiobacillus_phage	8.6e-09	24.5
WP_003602298.1\|970109_972299_+	recombinase family protein	A0A1B2LRQ3	Wolbachia_phage	3.1e-12	28.1

DBSCAN-SWA_58

975382 : 976081

Bacillus_virus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_003602290.1\|975382_976081_+	NUDIX hydrolase	G3MA14	Bacillus_virus	3.0e-17	27.9

DBSCAN-SWA_59

989636 : 991529

Bacillus_virus(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_012754224.1\|989636_991529_-	EAL domain-containing protein	G3MA91	Bacillus_virus	3.9e-19	35.9

DBSCAN-SWA_60

995620 : 995944

Pseudomonas_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_003605653.1\|995620_995944_+	hypothetical protein	A0A0S0N7T5	Pseudomonas_phage	4.6e-05	38.2

DBSCAN-SWA_61

1001682 : 1008624

Bacillus_phage(25.0%)

transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_003606519.1\|1001682_1002762_-	GGDEF domain-containing protein	A0A127AWB9	Bacillus_phage	1.6e-17	36.5
WP_012754227.1\|1003247_1004411_+	hypothetical protein	NA	NA	NA	NA
WP_050772732.1\|1004462_1004873_+	HNH endonuclease	A0A223W0A5	Agrobacterium_phage	2.1e-10	36.4
WP_043766665.1\|1004869_1005496_-	recombinase family protein	A0A0A7NPV4	Enterobacteria_phage	1.3e-35	50.5
WP_043765841.1\|1005633_1008624_+\|transposase	Tn3-like element ISMex22 family transposase	A0A1B0V7H9	Salmonella_phage	1.7e-157	35.3

DBSCAN-SWA_62

1013880 : 1014990

Rhizobium_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_012754231.1\|1013880_1014990_+	DNA phosphorothioation system sulfurtransferase DndC	R9TRT5	Rhizobium_phage	3.6e-17	27.6

DBSCAN-SWA_63

1022462 : 1023290

Mycobacterium_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_012754238.1\|1022462_1023290_+	hypothetical protein	A0A0B5A3N8	Mycobacterium_phage	1.4e-05	34.8

DBSCAN-SWA_64

1027260 : 1029594

Clostridium_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_158022492.1\|1027260_1029594_-	SEL1-like repeat protein	A0A0A7RWA3	Clostridium_phage	1.3e-21	37.9

DBSCAN-SWA_65

1034626 : 1039990

Bacillus_phage(50.0%)

transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_012754247.1\|1034626_1037977_+	UvrD-helicase domain-containing protein	A7KV33	Bacillus_phage	2.0e-02	39.4
WP_043767861.1\|1039060_1039990_+\|transposase	IS110 family transposase	A0A1S7J231	Thermus_phage	4.1e-14	29.9

DBSCAN-SWA_66

1061229 : 1065067

uncultured_Caudovirales_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_012754270.1\|1061229_1062510_-	sodium:proton antiporter	A0A2H4J178	uncultured_Caudovirales_phage	2.3e-39	39.9
WP_012754271.1\|1062534_1062798_-	hypothetical protein	NA	NA	NA	NA
WP_158022506.1\|1063858_1065067_+	Na+/H+ antiporter NhaA	A0A2H4J5W3	uncultured_Caudovirales_phage	1.0e-113	61.7

DBSCAN-SWA_67

1097525 : 1151823

uncultured_Mediterranean_phage(30.0%)

transposase,integrase

attL 1092363:1092381|attR 1162944:1162962

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
1092363:1092381	attL	NA	NA	NA	NA
WP_012754319.1\|1097525_1098107_-	metallophosphoesterase	A0A0P0IYW4	Pseudomonas_phage	4.6e-24	39.6
WP_158022495.1\|1098199_1099462_-\|integrase	integrase	NA	NA	NA	NA
WP_003596097.1\|1100139_1105398_+	DEAD/DEAH box helicase	A0A1B1IUF6	uncultured_Mediterranean_phage	2.5e-55	22.8
WP_003596095.1\|1105394_1108154_+	DEAD/DEAH box helicase	A0A1B1IUI1	uncultured_Mediterranean_phage	2.9e-31	26.2
WP_003596094.1\|1108153_1112143_+	N-6 DNA methylase	A0A1B1IUC6	uncultured_Mediterranean_phage	2.2e-40	23.5
WP_003596092.1\|1112139_1112946_+	HNH endonuclease	NA	NA	NA	NA
WP_085985459.1\|1113076_1114187_+\|transposase	IS3-like element ISMex1 family transposase	S5WIU1	Leptospira_phage	6.8e-48	40.7
WP_003596089.1\|1114502_1115711_+\|transposase	IS256-like element ISMex14 family transposase	A0A220NQR7	Corynebacterium_phage	4.9e-92	48.5
WP_003596081.1\|1115698_1116364_-	hypothetical protein	NA	NA	NA	NA
WP_085985481.1\|1116455_1117567_-\|transposase	IS3-like element ISMex1 family transposase	S5WIU1	Leptospira_phage	2.0e-47	40.3
WP_003596078.1\|1117899_1119093_+	hypothetical protein	NA	NA	NA	NA
WP_003596075.1\|1120680_1120947_+	hypothetical protein	NA	NA	NA	NA
WP_009867550.1\|1122453_1123722_+\|transposase	IS256-like element ISMex3 family transposase	A0A2P1JQX9	Mycobacterium_phage	2.5e-91	45.7
WP_003596073.1\|1124999_1125995_+	DMT family transporter	NA	NA	NA	NA
WP_003596072.1\|1126020_1127037_+	zinc-binding alcohol dehydrogenase family protein	NA	NA	NA	NA
WP_003596071.1\|1127151_1127469_+	cupin domain-containing protein	NA	NA	NA	NA
WP_003596070.1\|1127540_1128419_-	LysR family transcriptional regulator	NA	NA	NA	NA
WP_003596069.1\|1128508_1129255_-	L,D-transpeptidase	NA	NA	NA	NA
WP_003596067.1\|1129680_1130253_-	TetR/AcrR family transcriptional regulator	NA	NA	NA	NA
WP_003596066.1\|1130352_1130775_+	hypothetical protein	NA	NA	NA	NA
WP_003596065.1\|1130771_1131719_+	alpha/beta hydrolase	NA	NA	NA	NA
WP_003596064.1\|1131772_1132627_-	LysR family transcriptional regulator	NA	NA	NA	NA
WP_003596063.1\|1132727_1133729_+	zinc-dependent alcohol dehydrogenase family protein	NA	NA	NA	NA
WP_003596062.1\|1133818_1134928_+	hypothetical protein	NA	NA	NA	NA
WP_003596061.1\|1134940_1135378_+	cupin domain-containing protein	NA	NA	NA	NA
WP_003596060.1\|1135769_1136912_+	hypothetical protein	NA	NA	NA	NA
WP_012754324.1\|1137355_1137823_+	SDR family NAD(P)-dependent oxidoreductase	NA	NA	NA	NA
WP_003596058.1\|1137854_1138760_-	AraC family transcriptional regulator	NA	NA	NA	NA
WP_003596057.1\|1138896_1139640_+	SDR family oxidoreductase	NA	NA	NA	NA
WP_003596055.1\|1139653_1140007_+	VOC family protein	NA	NA	NA	NA
WP_003596053.1\|1141029_1141839_+	phosphonate ABC transporter ATP-binding protein	G9BWD6	Planktothrix_phage	1.0e-21	36.4
WP_003596052.1\|1141851_1142724_+	phosphate/phosphite/phosphonate ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_003596050.1\|1142727_1143561_+	phosphonate ABC transporter, permease protein PhnE	NA	NA	NA	NA
WP_003596049.1\|1143569_1144589_+	2-hydroxyacid dehydrogenase	NA	NA	NA	NA
WP_003596048.1\|1144616_1145486_+	LysR family transcriptional regulator	NA	NA	NA	NA
WP_003596046.1\|1145658_1146459_-	SDR family NAD(P)-dependent oxidoreductase	NA	NA	NA	NA
WP_043706435.1\|1146754_1147237_+	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_003596044.1\|1147812_1148850_+	transporter	NA	NA	NA	NA
WP_003596043.1\|1148903_1149350_+	hypothetical protein	NA	NA	NA	NA
WP_085985482.1\|1150639_1151823_-\|transposase	IS3-like element ISMex5 family transposase	S5WIU1	Leptospira_phage	1.6e-31	32.0
1162944:1162962	attR	NA	NA	NA	NA

DBSCAN-SWA_68

1178820 : 1179507

Caulobacter_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_003595982.1\|1178820_1179507_+	hypothetical protein	K4JRZ2	Caulobacter_phage	1.9e-24	35.8

DBSCAN-SWA_69

1186945 : 1190708

Emiliania_huxleyi_virus(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_003595967.1\|1186945_1187614_-	ribonuclease HII	D2TEQ2	Emiliania_huxleyi_virus	7.5e-18	36.0
WP_003595966.1\|1187624_1187873_-	hypothetical protein	NA	NA	NA	NA
WP_003595965.1\|1187869_1188079_-	hypothetical protein	NA	NA	NA	NA
WP_003595963.1\|1188075_1189272_-	AAA family ATPase	NA	NA	NA	NA
WP_003595962.1\|1189310_1189790_-	hypothetical protein	NA	NA	NA	NA
WP_003595959.1\|1189814_1190708_-	RNA ligase family protein	U5PS25	Bacillus_phage	3.6e-07	31.5

DBSCAN-SWA_70

1197652 : 1198822

Ralstonia_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_003603642.1\|1197652_1198822_-	glutathionylspermidine synthase family protein	B2ZXR7	Ralstonia_phage	3.5e-63	38.0

DBSCAN-SWA_71

1203405 : 1216419

Bacillus_phage(25.0%)

transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_003603637.1\|1203405_1205121_+	type I secretion system permease/ATPase	W8CYL7	Bacillus_phage	1.3e-21	24.1
WP_003603635.1\|1205120_1206416_+	HlyD family type I secretion periplasmic adaptor subunit	NA	NA	NA	NA
WP_003603633.1\|1206517_1208557_+	response regulator	A0A1V0SGX0	Hokovirus	5.4e-43	31.7
WP_003603631.1\|1208615_1209122_+	hypothetical protein	NA	NA	NA	NA
WP_012754339.1\|1209233_1210160_+	hypothetical protein	NA	NA	NA	NA
WP_003605542.1\|1210164_1210698_+	hypothetical protein	NA	NA	NA	NA
WP_003605543.1\|1210782_1211448_+	hypothetical protein	NA	NA	NA	NA
WP_003605544.1\|1211550_1213146_+	RNA polymerase sigma factor RpoD/SigA	F4YCU2	Synechococcus_phage	4.8e-39	40.5
WP_012754340.1\|1213204_1214818_+	pentapeptide repeat-containing protein	NA	NA	NA	NA
WP_003605548.1\|1214844_1215225_+	hypothetical protein	NA	NA	NA	NA
WP_003605550.1\|1215291_1216419_-\|transposase	transposase	A0A7E5	Microcystis_virus	1.7e-22	36.2

DBSCAN-SWA_72

1244469 : 1245477

uncultured_Mediterranean_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_003603519.1\|1244469_1245477_+	hypothetical protein	A0A1B1IPE0	uncultured_Mediterranean_phage	1.3e-74	45.5

DBSCAN-SWA_73

1251304 : 1255040

Orpheovirus(50.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_003604198.1\|1251304_1251934_+	hypothetical protein	A0A2I2L698	Orpheovirus	7.5e-20	34.6
WP_003604200.1\|1252100_1252607_+	hypothetical protein	NA	NA	NA	NA
WP_003604201.1\|1252927_1253350_+	hypothetical protein	NA	NA	NA	NA
WP_003604202.1\|1253420_1255040_+	AAA family ATPase	E3T5P9	Cafeteria_roenbergensis_virus	9.3e-06	27.1

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

3. NC_012809

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

0 : 1732

Enterobacteria_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_043766665.1\|1105_1732_+	recombinase family protein	A0A0A7NPV4	Enterobacteria_phage	1.3e-35	50.5

DBSCAN-SWA_2

5131 : 20937

Vibrio_phage(12.5%)

transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_043768327.1\|5131_5785_-	ParA family protein	D4HTX7	Vibrio_phage	3.0e-11	29.6
WP_043768329.1\|6089_7046_-	toll/interleukin-1 receptor domain-containing protein	NA	NA	NA	NA
WP_012753464.1\|7340_7667_+	type II toxin-antitoxin system RelE/ParE family toxin	A0A141GEX6	Brucella_phage	5.4e-14	43.8
WP_043768332.1\|7666_7984_+	transcriptional regulator	NA	NA	NA	NA
WP_012753466.1\|8031_9714_+	DUF262 domain-containing protein	NA	NA	NA	NA
WP_043768335.1\|9720_10161_-	hypothetical protein	A0A097EYP5	Mycobacterium_phage	1.3e-15	41.3
WP_012753468.1\|10165_10750_-	recombinase family protein	E5FFF9	Burkholderia_phage	8.5e-42	51.1
WP_082222874.1\|10998_11883_-	LysR family transcriptional regulator	NA	NA	NA	NA
WP_043768345.1\|13299_14052_-\|transposase	IS6-like element ISMex25 family transposase	A0A0N9SKD3	Staphylococcus_phage	1.5e-30	38.0
WP_050772750.1\|14048_14519_-	hypothetical protein	NA	NA	NA	NA
WP_043768348.1\|14950_15436_+	hypothetical protein	NA	NA	NA	NA
WP_043768352.1\|15624_16194_-	recombinase family protein	A0A219YA40	Aeromonas_phage	1.1e-33	47.8
WP_043768356.1\|16351_19315_+\|transposase	Tn3 family transposase	A0A1B0V7H9	Salmonella_phage	7.3e-182	38.1
WP_012753471.1\|19595_19898_-	type II toxin-antitoxin system RelE/ParE family toxin	NA	NA	NA	NA
WP_158022513.1\|19922_20354_-	hypothetical protein	NA	NA	NA	NA
WP_043768363.1\|20376_20937_-	recombinase family protein	M9Q1K0	Clostridium_phage	4.8e-26	40.3

DBSCAN-SWA_3

27532 : 35793

Saccharomonospora_phage(25.0%)

transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_043768368.1\|27532_27964_-\|transposase	IS200/IS605-like element ISMex34 family transposase	I4AZI8	Saccharomonospora_phage	4.0e-12	31.7
WP_043768370.1\|28368_28686_+	integration host factor subunit beta	A0A249Y2G7	Serratia_phage	1.0e-09	40.0
WP_043768371.1\|29086_29419_-	four-helix bundle copper-binding protein	NA	NA	NA	NA
WP_012753486.1\|29655_30360_-	hypothetical protein	NA	NA	NA	NA
WP_012753487.1\|30374_33269_-	Ti-type conjugative transfer relaxase TraA	V5UQN3	Mycobacterium_phage	2.1e-08	23.9
WP_043768374.1\|33503_33785_+	hypothetical protein	NA	NA	NA	NA
WP_012753488.1\|33781_34039_+	hypothetical protein	NA	NA	NA	NA
WP_012753489.1\|34048_34381_+	conjugal transfer protein TraD	NA	NA	NA	NA
WP_158022514.1\|34337_34637_+	conjugal transfer protein TraD	NA	NA	NA	NA
WP_043768345.1\|35040_35793_-\|transposase	IS6-like element ISMex25 family transposase	A0A0N9SKD3	Staphylococcus_phage	1.5e-30	38.0

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

4. NC_012810

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

0 : 9746

Mycobacterium_phage(33.33%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_158022516.1\|2063_3713_+	hypothetical protein	NA	NA	NA	NA
WP_158022519.1\|3681_4578_+	hypothetical protein	NA	NA	NA	NA
WP_012753493.1\|4567_5257_+	hypothetical protein	NA	NA	NA	NA
WP_012753494.1\|5358_5592_+	hypothetical protein	NA	NA	NA	NA
WP_043768391.1\|5596_6022_-	hypothetical protein	G8I4T1	Mycobacterium_phage	2.5e-11	36.8
WP_012753496.1\|6276_6924_+	ParA family protein	B0ZSI1	Halomonas_phage	4.7e-09	31.3
WP_012753497.1\|6923_7295_+	hypothetical protein	NA	NA	NA	NA
WP_012753498.1\|7341_7893_+	hypothetical protein	NA	NA	NA	NA
WP_158022517.1\|7959_8445_-	hypothetical protein	NA	NA	NA	NA
WP_043768398.1\|8495_8678_-	hypothetical protein	NA	NA	NA	NA
WP_012753501.1\|8978_9746_+	GntR family transcriptional regulator	A0A0A8IK91	Aurantimonas_phage	2.2e-13	33.0

DBSCAN-SWA_2

12782 : 13049

Burkholderia_phage(100.0%)

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_012753506.1\|12782_13049_+	pyocin activator PrtN family protein	I6NSR8	Burkholderia_phage	8.9e-23	64.6

DBSCAN-SWA_3

19477 : 23444

Clostridium_phage(50.0%)

tail

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_082222876.1\|19477_20158_-	recombinase family protein	M9Q1K0	Clostridium_phage	1.4e-27	48.8
WP_012753519.1\|20310_20586_-	hypothetical protein	NA	NA	NA	NA
WP_043768404.1\|20572_20797_-	hypothetical protein	NA	NA	NA	NA
WP_012753521.1\|20997_21303_+	helix-turn-helix transcriptional regulator	NA	NA	NA	NA
WP_085985484.1\|21299_22766_+\|tail	phage tail length tape measure family protein	NA	NA	NA	NA
WP_043766665.1\|22817_23444_-	recombinase family protein	A0A0A7NPV4	Enterobacteria_phage	1.3e-35	50.5

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

5. NC_012808

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Crispr_ID: NC_012808_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_012808_1

703389-703475

Orphan

Consensus_repeat	Method
TATGGCGGTTATTACGGCTACGGC	CRISPRCasFinder

1 spacers

The CRISPR arrays of NC_012808_1

>merge|NC_012808|1|703389-703475|CRISPRCasFinder
TATGGCGGTTATTACGGCTACGGCGTCCCCGTCGGCTATTACGGCGGCTACGGCTACCCGGTTTATGGCGGCTATTACGGCTACGGC

>NC_012808|1|1|703389-703475|CRISPRCasFinder
TATGGCGGTTATTACGGCTACGGC	GTCCCCGTCGGCTATTACGGCGGCTACGGCTACCCGGTT
TATGGCGGCTATTACGGCTACGGC

Protein	Signature genes	Signature genes Name	Protein_function
NC_012808.1\|WP_003598885.1\|695717_696536_-\|inositol-monophosphatase	unknown	unknown	gnl\|CDD\|223559
NC_012808.1\|WP_012752173.1\|707779_708607_-\|adenosylcobinamide-GDP-ribazoletransferase	unknown	unknown	gnl\|CDD\|234697
NC_012808.1\|WP_003598877.1\|700433_701417_+\|asparaginase	unknown	unknown	gnl\|CDD\|199208
NC_012808.1\|WP_003598880.1\|698741_699344_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|227315
NC_012808.1\|WP_012605861.1\|695042_695666_+\|membrane-integrity-associated-transporter-subunit-PqiC	unknown	unknown	gnl\|CDD\|225759
NC_012808.1\|WP_003603741.1\|708774_709812_+\|nicotinate-nucleotide--dimethylbenzimidazole-phosphoribosyltransferase	unknown	unknown	gnl\|CDD\|234636
NC_012808.1\|WP_012752168.1\|697522_697711_-\|hypothetical-protein	unknown	unknown	unknown
NC_012808.1\|WP_003598862.1\|706820_707033_-\|DUF1289-domain-containing-protein	unknown	unknown	gnl\|CDD\|377738
NC_012808.1\|WP_003598878.1\|699651_700404_+\|16S-rRNA-(uracil(1498)-N(3))-methyltransferase	unknown	unknown	gnl\|CDD\|236959
NC_012808.1\|WP_003598881.1\|697754_698705_-\|4-hydroxybenzoate-octaprenyltransferase	unknown	unknown	gnl\|CDD\|183808
NC_012808.1\|WP_003598872.1\|703569_703836_+\|sulfurtransferase-TusA-family-protein	unknown	unknown	gnl\|CDD\|238180
NC_012808.1\|WP_003598865.1\|705445_705886_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|153095
NC_012808.1\|WP_012252619.1\|704898_705297_+\|DUF3775-domain-containing-protein	unknown	unknown	gnl\|CDD\|378888
NC_012808.1\|WP_003603743.1\|709818_711360_-\|HAMP-domain-containing-histidine-kinase	unknown	unknown	gnl\|CDD\|223715
NC_012808.1\|WP_003598870.1\|703875_704442_+\|NUDIX-hydrolase	unknown	unknown	gnl\|CDD\|239516
NC_012808.1\|WP_003598864.1\|706131_706824_-\|TIGR02281-family-clan-AA-aspartic-protease	unknown	unknown	gnl\|CDD\|226106
NC_012808.1\|WP_003598876.1\|701603_702974_+\|glutamate--cysteine-ligase	unknown	unknown	gnl\|CDD\|178221
NC_012808.1\|WP_003598883.1\|696901_697402_+\|hypothetical-protein	unknown	unknown	unknown
NC_012808.1\|WP_003598888.1\|693839_694922_+\|MCE-family-protein	unknown	unknown	gnl\|CDD\|224380
NC_012808.1\|WP_012752172.1\|707087_707765_-\|hypothetical-protein	unknown	unknown	unknown

Protein	Function_ID	Function_description	E-value
NC_012808.1\|WP_003598885.1\|695717_696536_-\|inositol-monophosphatase	gnl\|CDD\|223559	COG0483, SuhB, Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family [Carbohydrate transport and metabolism].	1.28746e-64
NC_012808.1\|WP_012752173.1\|707779_708607_-\|adenosylcobinamide-GDP-ribazoletransferase	gnl\|CDD\|234697	PRK00235, cobS, cobalamin synthase; Reviewed.	1.49959e-49
NC_012808.1\|WP_003598877.1\|700433_701417_+\|asparaginase	gnl\|CDD\|199208	cd08964, L-asparaginase_II, Type II (periplasmic) bacterial L-asparaginase. Asparaginases (amidohydrolases, E.C. 3.5.1.1) are enzymes that catalyze the hydrolysis of asparagine to aspartic acid and ammonia. In bacteria, there are two classes of amidohydrolases. This model represents type II L-asparaginases, which tend to be highly specific for asparagine and localized to the periplasm. They are potent antileukemic agents and have been used in the treatment of acute lymphoblastic leukemia (ALL), but not without severe side effects. Tumor cells appear to have a heightened dependence on exogenous L-aspartate, and depleting their surroundings of L-aspartate may starve cancerous ALL cells. Type II L-asparaginase acts as a tetramer, which is actually a dimer of two tightly bound dimers. A conserved threonine residue is thought to supply the nucleophile hydroxy-group that attacks the amide bond. Many bacterial L-asparaginases have both L-asparagine and L-glutamine hydrolysis activities, to a different degree, and some of them are annotated as asparaginase/glutaminase.	3.51018e-108
NC_012808.1\|WP_003598880.1\|698741_699344_-\|hypothetical-protein	gnl\|CDD\|227315	COG4982, COG4982, 3-oxoacyl-[acyl-carrier protein].	0.00319042
NC_012808.1\|WP_012605861.1\|695042_695666_+\|membrane-integrity-associated-transporter-subunit-PqiC	gnl\|CDD\|225759	COG3218, COG3218, ABC-type uncharacterized transport system, auxiliary component [General function prediction only].	4.48648e-40
NC_012808.1\|WP_003603743.1\|709818_711360_-\|HAMP-domain-containing-histidine-kinase	gnl\|CDD\|223715	COG0642, BaeS, Signal transduction histidine kinase [Signal transduction mechanisms].	1.98996e-52
NC_012808.1\|WP_003598862.1\|706820_707033_-\|DUF1289-domain-containing-protein	gnl\|CDD\|377738	pfam06945, DUF1289, Protein of unknown function (DUF1289). This family consists of a number of hypothetical bacterial proteins. The aligned region spans around 56 residues and contains 4 highly conserved cysteine residues towards the N-terminus. The function of this family is unknown. Structural modelling suggests this domain may bind nucleic acids.	5.71069e-18
NC_012808.1\|WP_003603741.1\|708774_709812_+\|nicotinate-nucleotide--dimethylbenzimidazole-phosphoribosyltransferase	gnl\|CDD\|234636	PRK00105, cobT, nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase; Reviewed.	7.95149e-148
NC_012808.1\|WP_003598878.1\|699651_700404_+\|16S-rRNA-(uracil(1498)-N(3))-methyltransferase	gnl\|CDD\|236959	PRK11713, PRK11713, 16S ribosomal RNA methyltransferase RsmE; Provisional.	1.58347e-73
NC_012808.1\|WP_003598881.1\|697754_698705_-\|4-hydroxybenzoate-octaprenyltransferase	gnl\|CDD\|183808	PRK12878, ubiA, 4-hydroxybenzoate octaprenyltransferase.	1.1333e-150
NC_012808.1\|WP_012252619.1\|704898_705297_+\|DUF3775-domain-containing-protein	gnl\|CDD\|378888	pfam12616, DUF3775, Protein of unknown function (DUF3775). This domain family is found in bacteria, and is approximately 80 amino acids in length. There is a single completely conserved residue G that may be functionally important.	3.08823e-21
NC_012808.1\|WP_003598865.1\|705445_705886_-\|hypothetical-protein	gnl\|CDD\|153095	cd04706, PLA2_plant, PLA2_plant: Plant-specific sub-family of Phospholipase A2, a super-family of secretory and cytosolic enzymes; the latter are either Ca dependent or Ca independent. Enzymatically active PLA2 cleaves the sn-2 position of the glycerol backbone of phospholipids; secreted PLA2s have also been found to specifically bind to a variety of soluble and membrane proteins in mammals, including receptors. As a toxin, PLA2 is a potent presynaptic neurotoxin which blocks nerve terminals by binding to the nerve membrane and hydrolyzing stable membrane lipids. The products of the hydrolysis cannot form bilayers leading to a change in membrane conformation and ultimately to a block in the release of neurotransmitters. PLA2 may form dimers or oligomers. This sub-family does not appear to have a conserved active site and metal-binding loop.	5.34284e-09
NC_012808.1\|WP_003598870.1\|703875_704442_+\|NUDIX-hydrolase	gnl\|CDD\|239516	cd03424, ADPRase_NUDT5, ADP-ribose pyrophosphatase (ADPRase) catalyzes the hydrolysis of ADP-ribose and a variety of additional ADP-sugar conjugates to AMP and ribose-5-phosphate. Like other members of the Nudix hydrolase superfamily, it requires a divalent cation, such as Mg2+, for its activity. It also contains a highly conserved 23-residue Nudix motif (GX5EX7REUXEEXGU, where U = I, L or V) which functions as a metal binding site/catalytic site. In addition to the Nudix motif, there are additional conserved amino acid residues, distal from the signature sequence, that correlate with substrate specificity. In humans, there are four distinct ADPRase activities, three putative cytosolic enzymes (ADPRase-I, -II, and -Mn) and a single mitochondrial enzyme (ADPRase-m). Human ADPRase-II is also referred to as NUDT5. It lacks the N-terminal target sequence unique to mitochondrial ADPRase. The different cytosolic types are distinguished by their specificities for substrate and specific requirement for metal ions. NUDT5 forms a homodimer.	2.82993e-39
NC_012808.1\|WP_003598864.1\|706131_706824_-\|TIGR02281-family-clan-AA-aspartic-protease	gnl\|CDD\|226106	COG3577, COG3577, Predicted aspartyl protease [General function prediction only].	1.96874e-48
NC_012808.1\|WP_003598876.1\|701603_702974_+\|glutamate--cysteine-ligase	gnl\|CDD\|178221	PLN02611, PLN02611, glutamate--cysteine ligase.	0
NC_012808.1\|WP_003598872.1\|703569_703836_+\|sulfurtransferase-TusA-family-protein	gnl\|CDD\|238180	cd00291, SirA_YedF_YeeD, SirA, YedF, and YeeD. Two-layered alpha/beta sandwich domain. SirA (also known as UvrY, and YhhP) belongs to a family of bacterial two-component response regulators that controls secondary metabolism and virulence. The other member of this two-component system is a sensor kinase called BarA which phosphorylates SirA. A variety of microorganisms have similar proteins, all of which contain a common CPxP sequence motif in the N-terminal region. YhhP is suggested to be important for normal cell division and growth in rich nutrient medium. Moreover, despite a low primary sequence similarity, the YccP structure closely resembles the non-homologous C-terminal RNA-binding domain of E. coli translation initiation factor IF3. The signature CPxP motif serves to stabilize the N-terminal helix as part of the N-capping box and might be important in mRNA-binding.	3.45402e-21
NC_012808.1\|WP_003598888.1\|693839_694922_+\|MCE-family-protein	gnl\|CDD\|224380	COG1463, Ttg2C, ABC-type transport system involved in resistance to organic solvents, periplasmic component [Secondary metabolites biosynthesis, transport, and catabolism].	1.51792e-30

>NC_012808.1|WP_003598876.1|701603_702974_+|glutamate--cysteine-ligase
MARDTSDTTPLTTRDELIAWFAAGEKPRARFAIGTEHEKIPFYTADHMPVPYEGERGIRALLENLGRETGWEPILDAGNIIGLAGPEGGGAISIEPGGQFELSGAPLPDIHATATELDEHLAATKRAAEPLGIGFLDLGMSPKWTREATPQMPKSRYRIMRNYMPKVGKLGLDMMLRTATVQVNVDFASEADMVRKMRVSLALQPIATALFANSPFTDGRPNGFLSRRSEIWRDTDPDRTGMLAFAFDEGFGYEAYADWLLDVPMYFVKRGETYHDVAGASFRDLMAGRLAQLPGERATVSDWANHASTVFPEVRLKRFLEMRGADVGGPAMIAAQSAFWVGLLYDETALSAAWDLVRGWSASERESMRAAVPRLGLHASIGGRCLGAVAAEALAIARTGLQARARRDGNGRDEAVYLQPLEAIVAAGRSHAQERLADYEGPWEKSVDPAFTTCTF
>NC_012808.1|WP_003598877.1|700433_701417_+|asparaginase
MTLPRILLLSLGGTITMTRSLEGGIVPTLTAADLADSVPGLAAVASIETLSPLRRPSAGLTLDDLIGVACTLNERLAGDLDGAVVIQGTDTIEETAFVLESLVAGDKPVVVTGAMRGPESAGADGPGNLLAATIVAGSGAARGMGVLAVLNDEIHAARLVQKAHTALPSAFRSPLAGPVGLVIEGEARIFLRSHRSLTLTGPFTDEPTPVALLKMGIGDDGRLLAALPDLGFAGVVIEGMGAGHVPEALAEIVSTLIARLPVVLASRTETGPVFSRTYGYPGGEIDLLGRGALSAGILSGVKARLMLQLLLRAGVDRAAYGAYFADR
>NC_012808.1|WP_003598878.1|699651_700404_+|16S-rRNA-(uracil(1498)-N(3))-methyltransferase
MAAYDFTAPRLFVEADLAEGRVLPLERAQANYLLTVLRRAEGEPVLLFNGRDGEWRAEIVPQGRKSADLRVVAQTRPQPAPADLHYLFAPLKTGRIDYMAQKAVEMGAGRLQPVFTRFTQGERIKLDRLQANAIEAAEQCGILSVPEIGEPARLPACLDALEANRLLVFCDEDASVTDPVAALRGAADPANPPPLAVLVGPEGGFHAEERALIAARPNTVALSLGPRILRADTAAVAVLALVQAVLGDAR
>NC_012808.1|WP_003598880.1|698741_699344_-|hypothetical-protein
MSARIVAPTKTAAALVGLVLLAGPALAQSMGGMPLPSMDTPAEPAPSAGAPMSVPAPMAPAAPAQSVPQQAGTDCSSIQKTLIERKNLVAKANSASNSKKKMTPQEACSLFGQLQANGATGIKWITANKEWCSIPDSFSEGFKADHNKVAAIRTKVCGIAAQATKMEAQAKTQAQNGGGGGGLLGGPGLSGAFRMPQGAL
>NC_012808.1|WP_003598881.1|697754_698705_-|4-hydroxybenzoate-octaprenyltransferase
MPSPSEPGSGRVADAVAGHWADRLAPAGARPYLRLARIERPIGWWLLLLPCWWSAALAATAAGNPGPHLGHLVLFLIGAVAMRGAGSTYNDIADRKLDAQVERTRSRPLPSGQVTTKQAAAFLVAQALVGLAVLLQFNATAILVGMLSLAPVAIYPFMKRVMPMPQAVLGLAFGWGALMGWVAVFGRLDPPALWLYAGTICWIVGYDTIYAVQDIEDDEIVGIHSSARLFGARLRLAVGLCYAGTIALFVPALIGAGAGLLSWLGLGLFAAHLARQVMHLSERDGLRALALFRSNRDAGLILFAGLAADALWQGLH
>NC_012808.1|WP_012752168.1|697522_697711_-|hypothetical-protein
MSETDPHRPPDDPITQGARARIQGRPRDACPYPVNSPERTAWLEGYDGSPADRSPDRPLDNG
>NC_012808.1|WP_003598883.1|696901_697402_+|hypothetical-protein
MMTFEIMNQNCRPGGEDEMSAPCITVQATPLPVLGAAHGLAPVGVALAFADDAADACGEDRFSLLLVDGEGEVTMRLGPFPEEDVVAVWRDISTTGGLARMLLREDGAIVPVSQQLGPVVLGKGRQRRRHAALSGRRPRFLVRRKPARLPARPCIHRGESEIISRG
>NC_012808.1|WP_003598885.1|695717_696536_-|inositol-monophosphatase
MTQTTSSLAALRPVLHDAIREAAALALPFFRQGDQTSARVWSKAGGSPVTEADVAVDTFLKIRLSQIEPRAAWLSEETSDDPVRLGHDFVWIVDPIDGTRAFLSGHPDWSIAVALLARGEPVLGGVFAPATEQFYEAVAGEGATLNGAPIRVAPQATLEGARITGPKPMQDRLLDGAARLGPRPSVTVVDRVPSLALRLARVAEGRIDLGLVSRDARDWDLAGADLIVREAGGVVCDLQGRPAVYNRPEPRHGELIAVPLPLRDPALAALEA
>NC_012808.1|WP_012605861.1|695042_695666_+|membrane-integrity-associated-transporter-subunit-PqiC
MTRLPLSPALPGRHLSGRILRAGALLAPLALLGGCGGGTPLTFDLAALPGQARAGGAARSIVVSEPVGLQPMEADRIIVREPGGSLSFLGGGQWADRLPRLIQTRVIQSLENTGRLRSVSRPSDKVPSDYQLVSEIREFDVNSGTGEAVVDLSAKLIAEGTGRVVNARVFTARVPVKKVDPQSAAAGLDAALGQVLADLVRWVNTAR
>NC_012808.1|WP_003598888.1|693839_694922_+|MCE-family-protein
METRANYVLIGAFTIGVVLAAFGFVFWLQGGSRGQATQALRIVFSGSVGGLAKGSTVSFNGIKVGEALDVRLLPQDPRRVVAIVQVDPSTPLRADTRARLDSAMLTGVSQIALSGGSADAPALTPGSGDKMPTIFADSSDIQDMMAAAKQIAQRADDVLQRLDKVVAGNEGAINRTLANVESFSKTLAEAGPSIAGLVKSVDGQRLNRVIENAETFSTALANSSGDIQAGLHDARSLAAKLNASADKIDGVLKGAEGFLGSASGQQGAGTFAEIREAAISVRDAGRAFRALSENLDKRTANISTSFNRLSGTSRREVEALSSDGQRTLNTLSRAARSLERDPSQVIFGGKPSLPEYNGGR
>NC_012808.1|WP_003598872.1|703569_703836_+|sulfurtransferase-TusA-family-protein
MSEISQDGTVELDLSGLKCPLPALRTRKALRALAPGARLAVTATDPLAGIDIPNVVREEGAALEALERHGPAARFLIRRGVDRPPAQA
>NC_012808.1|WP_003598870.1|703875_704442_+|NUDIX-hydrolase
MPPEIRGTRTVHDGWATFLVAEVTTPEGAAVTREIEDHGEAVCVLPYDPERKVALLIRQFRAPPFFTAGVTDLLEVPAGLLDEADPAEGVRREAFEETGLRLSHLEPVSTVWSVPGISTERMHLYLAPYAESDREGPGGGLAEEHEAITVVEMPLSTLAAMSEAGEIVDMKTLVLLLSLRLRRPELFA
>NC_012808.1|WP_012252619.1|704898_705297_+|DUF3775-domain-containing-protein
MDIALDKITEIILRLRAVEVKEGATDPDSGSNPTDDGSIDMLVGGTDDATEQEIRSMIAGLNEDERADLGALLYIGRGDYEAAEWHTAVNFAKEREAAGDTVIRELLGTPDAAPLLEEGLDALGIPMEPPEA
>NC_012808.1|WP_003598865.1|705445_705886_-|hypothetical-protein
MAILPYRAARRLPLVAGLSAVLLGLAPLAVSAQSVVTPDVEAPPVEAPTAPDLGNGLPQGALVFHGNYCGPGSRGAGLPPIDALDRACMHHDACSPPVGQGLPTCSCNDQLAREARQVARTPRIDDELRTAAEFVAVGAKALACEP
>NC_012808.1|WP_003598864.1|706131_706824_-|TIGR02281-family-clan-AA-aspartic-protease
MMWAALAILGVGLAVLIANHDGGPVMGLDSDQLAGVVSMTALLLLLVAGRWRQALVMPGKTLASILIWLAIGAVIVVGYTYRDDAQRVGANVVGALRPGTAVVGPGGEVTITRRSDGDFAVLAAVNGGAEQRFVFDTGASSVVLTAETAERLGIRPPESAFTQRVSTANGTALTAPIRLDSITVGPITERNVNAMVSRPGMLTTNLLGQSFLDRLPSYEVRGDRLILRSR
>NC_012808.1|WP_003598862.1|706820_707033_-|DUF1289-domain-containing-protein
MLATPSKKPSSPCTKLCVLDAVTGLCEGCGRTRDEIGLWGSLSEAQRLAVMAALPERLRRAYPGREACAP
>NC_012808.1|WP_012752172.1|707087_707765_-|hypothetical-protein
MLEILRRLFQSRRVMAPSQAPSDSPLEAIDRADTAERIEILARGGFETEASTLETILDEYLNPDEIDPEDRRWVEAEVARAFARKRADEATWPLETDFDRLAIAFDTLDASGIIALHDAGYTRSDGISDAAEIYHQRRERGRASRGFVFYHGQDVEAVVCDQGLYLAFGAFDDRDATMAAIAAEIVAAVEAQGLRTHWEGDVGTRILVHPIHWLKRSPSDDPRAA
>NC_012808.1|WP_012752173.1|707779_708607_-|adenosylcobinamide-GDP-ribazoletransferase
MIERSGRDLGPPFPGAELVYDLAACLRFFTRLPVPPLPDEPAPYAAPDFRTVPRMLPLAGLLIAAPAALVLVLAWEIRLGPFVAAALALVALALITGAMHEDGLADVADGFGGGQSRERSLEIMRDSRIGAYGGTALFLGLALRAAMLATLLDRSGGLAAVSLLFAAALSRTVALLPLAILDPARPGGAGAAVGRPTRATLGIAGSICLILAGIAAALGLPPLGLGLALILAPLAAFGLSALAERKIGGQTGDVVGACQQVGEIAVLLALVAATA
>NC_012808.1|WP_003603741.1|708774_709812_+|nicotinate-nucleotide--dimethylbenzimidazole-phosphoribosyltransferase
MTSSPTPDTSPFADIRRLLTEMPGPDGDAVAAIRARDASLTKPPGALGRLEGLVEWLGAWQGKAKPTLDRPMVCVFAGSHGVVERGVSAFPAAVNRQMLDNFAAGGAAINQLCAAYGLGFRVFDLAVDLPTGDICSGPALDEKGCVATMAFGMEAVAAGTDCLAVGEMGIGNTTVAAAIYAALYGGEAEHWVGRGTGLDAAGLDRKAQAVRLALETHKDHLGDPLTILARLGGREIAAMAGAILAARLQRVPVVLDGYVATAAAAILHAADPHALDHCIAGHLSAEGAHGEVLERLGLKPVLSLDMRLGEASGAALALGLLKGALACHRDMATFEQAGVSGKSAD
>NC_012808.1|WP_003603743.1|709818_711360_-|HAMP-domain-containing-histidine-kinase
MADLTAEMVQRGRGPSSQEVAKRRGIAREMRSARERLTSTSGLERAFDTELLRLYAQYRVGAGIPLLILALMVAGASSIWVPAVTAAIWAAGAIAATTLMLLLSRRFLRQAPESLSLKHWGRAFVAAEFGQSAAWAMLLLVGVPEARTFALFGLVIVAAVTTMLAATVPVAALAGLVPLMLAALSLLIFSSDMDTMLLVAMTVASQLFFAGLARRLYASAVGTLQSRAEKDAIFAELEQAKANSDEARRRAEEANLAKSRFLATMSHELRTPLNAILGFSEVMKNEVFGAHVAPAYREYATDIHDSGMHLLNLINEILDLSRIEAGRYDLTEEAVQLAHTVEECRHMMTLRARSKGQTFASLIDDSLPRLWADERALRQIVLNLLSNAVKFTPPGGEITIKVGWTSSGGQYLSVKDSGPGIPEDELGTVMSSFGRGSLAIKTAEQGSGLGLPIVKGLIDLHGGGFQLKSKPREGTEVIVTFPASRGMDTLPAMTLAAEKAPAEAASARRARAA

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Crispr_ID: NC_012808_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_012808_2

1858141-1858385

Orphan

Consensus_repeat	Method
ACCCGGACAACGACGGCACCCTCGAC	CRISPRCasFinder

3 spacers

The CRISPR arrays of NC_012808_2

>merge|NC_012808|2|1858141-1858385|CRISPRCasFinder
ATCCGGACAAGGACGGCACGATCGATCTGAAGGAGGCCCTGGCCGCCGGCTCCGCTGCCTTCGACAAGCTCGATCCGGATAAGGACGGCACGCTCGACGCTAAGGAGCTGAAGGGCCGCGTCAGCGAGGCCGACCTCAAGAAGCTCGACCCGGACAACGACGGCACCCTCGACAAGAAGGAATACCTTGCCGCCGTCGAGGCGCAGTTCAAGGCCGCTAACCCGGACAACGACGGCACCATCGAC

>NC_012808|2|2|1858141-1858385|CRISPRCasFinder
ATCCGGACAAGGACGGCACGATCGAT	CTGAAGGAGGCCCTGGCCGCCGGCTCCGCTGCCTTCGACAAGCTCG
ATCCGGATAAGGACGGCACGCTCGAC	GCTAAGGAGCTGAAGGGCCGCGTCAGCGAGGCCGACCTCAAGAAGCTCG
ACCCGGACAACGACGGCACCCTCGAC	AAGAAGGAATACCTTGCCGCCGTCGAGGCGCAGTTCAAGGCCGCTA
ACCCGGACAACGACGGCACCATCGAC

Protein	Signature genes	Signature genes Name	Protein_function
NC_012808.1\|WP_003607156.1\|1869065_1869326_-\|PepSY-domain-containing-protein	unknown	unknown	gnl\|CDD\|379323
NC_012808.1\|WP_012752626.1\|1869475_1871014_+\|YifB-family-Mg-chelatase-like-AAA-ATPase	unknown	unknown	gnl\|CDD\|223679
NC_012808.1\|WP_003601812.1\|1849137_1850406_+\|ABC-transporter-substrate-binding-protein	unknown	unknown	gnl\|CDD\|274821
NC_012808.1\|WP_003601810.1\|1850572_1851559_+\|YVTN-family-beta-propeller-repeat-protein	unknown	unknown	gnl\|CDD\|274824
NC_012808.1\|WP_003601785.1\|1865992_1866316_-\|YbaB/EbfC-family-nucleoid-associated-protein	unknown	unknown	gnl\|CDD\|234669
NC_012808.1\|WP_003601795.1\|1858641_1859001_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|234609
NC_012808.1\|WP_003601808.1\|1851650_1852085_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|259872
NC_012808.1\|WP_003601790.1\|1862224_1862803_-\|polysaccharide-export-protein	unknown	unknown	gnl\|CDD\|224512
NC_012808.1\|WP_012752623.1\|1855200_1857720_+\|TonB-dependent-receptor	unknown	unknown	gnl\|CDD\|366183
NC_012808.1\|WP_012752625.1\|1866405_1868286_-\|DNA-polymerase-III-subunit-gamma/tau	unknown	unknown	gnl\|CDD\|236382
NC_012808.1\|WP_012752622.1\|1853119_1854013_+\|ABC-transporter-permease	unknown	unknown	gnl\|CDD\|163573
NC_012808.1\|WP_003601801.1\|1854023_1854653_+\|hypothetical-protein	unknown	unknown	unknown
NC_012808.1\|WP_003601804.1\|1852373_1853123_+\|ATP-binding-cassette-domain-containing-protein	unknown	unknown	gnl\|CDD\|274822
NC_012808.1\|WP_012752621.1\|1847616_1848327_-\|(5-formylfuran-3-yl)methyl-phosphate-synthase	unknown	unknown	gnl\|CDD\|235014
NC_012808.1\|WP_003607157.1\|1868542_1869031_+\|hypothetical-protein	unknown	unknown	unknown
NC_012808.1\|WP_003601806.1\|1852098_1852377_+\|hypothetical-protein	unknown	unknown	unknown
NC_012808.1\|WP_003601794.1\|1859104_1860661_-\|undecaprenyl-phosphate-glucose-phosphotransferase	unknown	unknown	gnl\|CDD\|274396
NC_012808.1\|WP_012752624.1\|1863024_1865439_+\|LPS-biosynthesis-protein	unknown	unknown	gnl\|CDD\|225747
NC_012808.1\|WP_003601792.1\|1860792_1862052_-\|glycosyltransferase-family-4-protein	unknown	unknown	gnl\|CDD\|340831
NC_012808.1\|WP_003601813.1\|1848372_1848906_-\|DUF3280-domain-containing-protein	unknown	unknown	gnl\|CDD\|371669

Protein	Function_ID	Function_description	E-value
NC_012808.1\|WP_003607156.1\|1869065_1869326_-\|PepSY-domain-containing-protein	gnl\|CDD\|379323	pfam13670, PepSY_2, Peptidase propeptide and YPEB domain. This region is likely to have a protease inhibitory function (personal obs:C Yeats). The name is derived from Peptidase & Bacillus subtilis YPEB.	1.17039e-13
NC_012808.1\|WP_012752626.1\|1869475_1871014_+\|YifB-family-Mg-chelatase-like-AAA-ATPase	gnl\|CDD\|223679	COG0606, COG0606, Predicted ATPase with chaperone activity [Posttranslational modification, protein turnover, chaperones].	0
NC_012808.1\|WP_003601812.1\|1849137_1850406_+\|ABC-transporter-substrate-binding-protein	gnl\|CDD\|274821	TIGR03863, PQQ_ABC_bind, ABC transporter, substrate binding protein, PQQ-dependent alcohol dehydrogenase system. Members of this protein family are putative substrate-binding proteins of an ABC transporter family that associates, in gene neighborhood and phylogenomic profile, with pyrroloquinoline-quinone (PQQ)-dependent degradation of certain alcohols, such as 2-phenylethanol in Pseudomonas putida U. [Transport and binding proteins, Carbohydrates, organic alcohols, and acids].	0
NC_012808.1\|WP_003601810.1\|1850572_1851559_+\|YVTN-family-beta-propeller-repeat-protein	gnl\|CDD\|274824	TIGR03866, PQQ_ABC_repeats, PQQ-dependent catabolism-associated beta-propeller protein. Members of this protein family consist of seven repeats each of the YVTN family beta-propeller repeat (see TIGR02276). Members occur invariably as part of a transport operon that is associated with PQQ-dependent catabolism of alcohols such as phenylethanol.	0
NC_012808.1\|WP_003601785.1\|1865992_1866316_-\|YbaB/EbfC-family-nucleoid-associated-protein	gnl\|CDD\|234669	PRK00153, PRK00153, YbaB/EbfC family nucleoid-associated protein.	2.3783e-38
NC_012808.1\|WP_003601795.1\|1858641_1859001_+\|hypothetical-protein	gnl\|CDD\|234609	PRK00068, PRK00068, hypothetical protein; Validated.	0.000154502
NC_012808.1\|WP_003601808.1\|1851650_1852085_+\|hypothetical-protein	gnl\|CDD\|259872	cd04210, Cupredoxin_like_1, Uncharacterized Cupredoxin-like subfamily. Cupredoxins contain type I copper centers and are involved in inter-molecular electron transfer reactions. Cupredoxins are blue copper proteins because they have an intense blue color due to the presence of a mononuclear type 1 (T1) copper site. Structurally, the cupredoxin-like fold consists of a beta-sandwich with 7 strands in 2 beta-sheets, which is arranged in a Greek-key beta-barrel. Some of these proteins have lost the ability to bind copper. Majority of family members contain multiple cupredoxin domain repeats; ceruloplasmin and coagulation factors V/VIII have six repeats; Laccase, ascorbate oxidase, and spore coat protein A, and multicopper oxidase CueO contain three repeats; and nitrite reductase has two repeats. Others are mono-domain cupredoxins, such as plastocyanin, pseudoazurin, plantacyanin, azurin, rusticyanin, stellacyanin, quinol oxidase and the periplasmic domain of cytochrome c oxidase subunit II.	2.06631e-07
NC_012808.1\|WP_003601790.1\|1862224_1862803_-\|polysaccharide-export-protein	gnl\|CDD\|224512	COG1596, Wza, Periplasmic protein involved in polysaccharide export, contains SLBB domain of b-grasp fold [Cell wall/membrane/envelope biogenesis].	1.70025e-30
NC_012808.1\|WP_012752623.1\|1855200_1857720_+\|TonB-dependent-receptor	gnl\|CDD\|366183	pfam00593, TonB_dep_Rec, TonB dependent receptor. This model now only covers the conserved part of the barrel structure.	1.7448e-33
NC_012808.1\|WP_012752625.1\|1866405_1868286_-\|DNA-polymerase-III-subunit-gamma/tau	gnl\|CDD\|236382	PRK09111, PRK09111, DNA polymerase III subunits gamma and tau; Validated.	0
NC_012808.1\|WP_012752622.1\|1853119_1854013_+\|ABC-transporter-permease	gnl\|CDD\|163573	TIGR03861, ABC_efflux_transporter_permease_protein, alcohol ABC transporter, permease protein. Members of this protein family, part of a larger class of efflux-type ABC transport permease proteins, are found exclusively in genomic contexts with pyrroloquinoline-quinone (PQQ) biosynthesis enzymes and/or PQQ-dependent alcohol dehydrogenases, such as the phenylethanol dehydrogenase PedE of Pseudomonas putida U. Members include PedC, an apparent phenylethanol transport protein whose suggested role is efflux to limit intracellular concentrations of toxic metabolites during phenylethanol catalysis. [Transport and binding proteins, Carbohydrates, organic alcohols, and acids].	4.94525e-117
NC_012808.1\|WP_003601794.1\|1859104_1860661_-\|undecaprenyl-phosphate-glucose-phosphotransferase	gnl\|CDD\|274396	TIGR03023, Sugar_transferase., Undecaprenyl-phosphate glucose phosphotransferase. This family of proteins encompasses the E. coli WcaJ protein involved in colanic acid biosynthesis, the Methylobacillus EpsB protein involved in methanolan biosynthesis, as well as the GumD protein involved in the biosynthesis of xanthan. All of these are closely related to the well-characterized WbaP (formerly RfbP) protein, which is the first enzyme in O-antigen biosynthesis in Salmonella typhimurium. The enzyme transfers galactose from UDP-galactose (NOTE: not glucose) to a polyprenyl carrier (utilizing the highly conserved C-terminal sugar transferase domain, pfam02397) a reaction which takes place at the cytoplasmic face of the inner membrane. The N-terminal hydrophobic domain is then believed to facilitate the "flippase" function of transferring the liposaccharide unit from the cytoplasmic face to the periplasmic face of the inner membrane. Most of these genes are found within large operons dedicated to the production of complex exopolysaccharides such as the enterobacterial O-antigen. Colanic acid biosynthesis utilizes a glucose-undecaprenyl carrier, knockout of EpsB abolishes incorporation of UDP-glucose into the lipid phase, and the C-terminal portion of GumD has been shown to be responsible for the glucosyl-1-transferase activity.	2.02286e-178
NC_012808.1\|WP_003601804.1\|1852373_1853123_+\|ATP-binding-cassette-domain-containing-protein	gnl\|CDD\|274822	TIGR03864, PQQ_ABC_ATP, ABC transporter, ATP-binding subunit, PQQ-dependent alcohol dehydrogenase system. Members of this protein family are the ATP-binding subunit of an ABC transporter system that is associated with PQQ biosynthesis and PQQ-dependent alcohol dehydrogenases. While this family shows homology to several efflux ABC transporter subunits, the presence of a periplasmic substrate-binding protein and association with systems for catabolism of alcohols suggests a role in import rather than detoxification. [Transport and binding proteins, Carbohydrates, organic alcohols, and acids].	9.2588e-127
NC_012808.1\|WP_012752621.1\|1847616_1848327_-\|(5-formylfuran-3-yl)methyl-phosphate-synthase	gnl\|CDD\|235014	PRK02227, PRK02227, (5-formylfuran-3-yl)methyl phosphate synthase.	2.6505e-75
NC_012808.1\|WP_012752624.1\|1863024_1865439_+\|LPS-biosynthesis-protein	gnl\|CDD\|225747	COG3206, GumC, Uncharacterized protein involved in exopolysaccharide biosynthesis [Cell envelope biogenesis, outer membrane].	9.57422e-76
NC_012808.1\|WP_003601792.1\|1860792_1862052_-\|glycosyltransferase-family-4-protein	gnl\|CDD\|340831	cd03801, GT4_PimA-like, phosphatidyl-myo-inositol mannosyltransferase. This family is most closely related to the GT4 family of glycosyltransferases and named after PimA in Propionibacterium freudenreichii, which is involved in the biosynthesis of phosphatidyl-myo-inositol mannosides (PIM) which are early precursors in the biosynthesis of lipomannans (LM) and lipoarabinomannans (LAM), and catalyzes the addition of a mannosyl residue from GDP-D-mannose (GDP-Man) to the position 2 of the carrier lipid phosphatidyl-myo-inositol (PI) to generate a phosphatidyl-myo-inositol bearing an alpha-1,2-linked mannose residue (PIM1). Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate residue. This group of glycosyltransferases is most closely related to the previously defined glycosyltransferase family 1 (GT1). The members of this family may transfer UDP, ADP, GDP, or CMP linked sugars. The diverse enzymatic activities among members of this family reflect a wide range of biological functions. The protein structure available for this family has the GTB topology, one of the two protein topologies observed for nucleotide-sugar-dependent glycosyltransferases. GTB proteins have distinct N- and C- terminal domains each containing a typical Rossmann fold. The two domains have high structural homology despite minimal sequence homology. The large cleft that separates the two domains includes the catalytic center and permits a high degree of flexibility. The members of this family are found mainly in certain bacteria and archaea.	1.78082e-46
NC_012808.1\|WP_003601813.1\|1848372_1848906_-\|DUF3280-domain-containing-protein	gnl\|CDD\|371669	pfam11684, DUF3280, Protein of unknown function (DUF2380). This family of proteins with unknown function appears to be restricted to Proteobacteria.	3.15992e-49

>NC_012808.1|WP_012752623.1|1855200_1857720_+|TonB-dependent-receptor
MRVLRGSLIASVALLPGHVMAQGAGGGQAVTLEEISVVSNTPVAASRRVVATQTPSGLREVTILDGIDRNKLPQNTSVLTSGDVSRVGFPSTVRALDERVGSISVNNAQGNPFQPTITYRGFEASPLGGSPQGVAVYLNGARFNTSFGDTVQWDLIPDIAVDRIELEGSNPAFGLNALGGSLAVTLKNGFTYQGSEINVLGGSFGRGAVAFQHGQRIDNIGLYVAGTKLGEDGWRKHSPSRLNQIYADLGVQGEKSEFHFNVIGASNSLTGNGTAPVELLKADRSDVFTYPDQTKNDFLRFQLSGTYDVTPTITVQGNAYYGLFRQRTANGDAADVENCEVDERFVCSEGADDNQFFLRDRTGSPVRTDRLRTFNFGGINPTFADRFDEGGPYAFLNQTRTSTDNFGATVQTVIRETPFGLPNRFVLGGQYDGGRTRFGADNSIGGLTLDRGFSPPGIVVSSDDGIITPVSVHTSNDYGGIYFSNNTDLTDRLTLTLQGRFNMAKIVLRDQIGTALNGDHYYQRFNPGVGATYKVIPDYLVAYGGYTEANRAPTPAELSCADPLAPCSLTNFFVGDPPLKQVVARTVEAGVRGRIPQPDEYFGGILSWKAGFFSTRNDDDILFVPAPDTIGRAFFRNVGSTKRQGVEASLFYNAPRWNAFIDYAFVDATFESPVELAAPGNPFNSAGGDESGVVLVRPGNRLPGVAPHQLKVGVQYQVTPEWRVGALARFATGKFLVGDPTNQNKTTGDFAVVGLNTSYRVASNIELYGYIENAFNANYATFGTFSPVNEVPIVRVPNATSNRSLAPGAPVAAFGGLRILFEPPPAAPVVEPFPLVRKG
>NC_012808.1|WP_003601801.1|1854023_1854653_+|hypothetical-protein
MIPRSVRAPLCLALILAAGPVLAQPKADPDWPCPQRKVTTLGYGSFWTGPDLAEAGEWGSDREAAQLARKLASRRTELREVDTLLDEFAQKADPAEKGKRLTRVFAGVFEIINGERSTVMNGISRYAQGQRRLAERIRDEADKVSEFKDSPESDSTKVASKEVADLESRFNWDRRIFDERNQSVSYVCEVPTILEQRLGEIARRIQAHL
>NC_012808.1|WP_012752622.1|1853119_1854013_+|ABC-transporter-permease
MRSPSNPAVAARAEDGAKPVPHAGRLDAVGYLIALGGIVRRELLRFFHQKERFFSAMVRPLVWLFIFAAGFRNTLGTSITPPYETYVLYEAYVVPGLAVMIQLFNGMQSSLSMVYDREVGSMKVLLTSPYPRWSLLLAKLVAGVSVSIVQAYAFLAIAWFWETGIPPLGYLAALPAFLASGLMLGAIGLFLSSLVRQLENFASVMNFVIFPMFFASSALYPLWQVRASSEWLYLICQANPFTHAVELVRFALYGRFEPVACAVVVGTGLLFFTLAAIAYDPGRGIMARRGGPAGEAA
>NC_012808.1|WP_003601804.1|1852373_1853123_+|ATP-binding-cassette-domain-containing-protein
MSAALEVAGVSHRFGQRAALSDVSITVERGHFMALLGPNGAGKTTLFSVITRLYNNQEGRVSILGHPLDREPSRALAGLGVVFQARTLDTDLTVAQNLHYHASLHGIGRAAARARIETLLARVGLAERRDDKIRTLSGGQSRRIEIARSLIHAPRLLLLDEPTVGLDLESRADIVAIVRALVREEGLSVLWATHIFEEISPEDDAVVLHKGRIVARGRAGEIGGPGETLEAAFRRLVAEPDKRAVKSAA
>NC_012808.1|WP_003601806.1|1852098_1852377_+|hypothetical-protein
MMRTRTSLAVPRGFRGSALLALVVLATPALADDKAACADGIAAVKARVEKLAPEAVPQKLKRALKIAEREQGEGEFDECLEALDDAKRALPK
>NC_012808.1|WP_003601808.1|1851650_1852085_+|hypothetical-protein
MRWTTRLGLAAAALMLAAAPAGALDLTKKRQNLPDLVLGNEEGNDFVVENKDIELEAGKAYRLRIVAKGRQEYKFYAPEFFRYIWFNQIVIEHKEIHGGGPPDHLEFDDPGEIAIEFVAIKPGAYKWYAQGLEEKGMAGTITVK
>NC_012808.1|WP_003601810.1|1850572_1851559_+|YVTN-family-beta-propeller-repeat-protein
MVARLRAGLGCALLAGVSLGSAGSAQAFTAYVTNEKANTVSVIDTETLAVTGTWKVGRRPRGVTLSKDDKELFVCASDDDRIDVLDTATGKVVRSLRSGPDPEQFILDQSGNPLYVANEDDSQVTILDIEKNKVLAEVPVGVEPEGMGLSPDGKILVNTSETTNMAHFIDTKTFEVIDNVLVDARPRFAEFSADGKFLWVSAEVGGTVSVIDVATRKVIKKITFKIPSVTDEQIQPVGVRLTKDGTRAFVALGPANRVAVVDAKTYEVQKYLPVGQRVWQLAFTPDEKQLYTTNGTSNDVSVIDVEGLKVVKSIPVGLLPWGVAISKK
>NC_012808.1|WP_003601812.1|1849137_1850406_+|ABC-transporter-substrate-binding-protein
MRLSVPLLLAAGLATGPAAFLAASIHARAQEPKAATGEPPPGSPANETPAPVPGSETHIAVLYRPVPAPSSYDAEADPEDLGVAGARMAVKDNNTTGRFTKQTFALDEVALDGERDPVEAAKALADKGVRFFVLALPAAEVLAVADALKETGAVILNAGAPDDRLRGADCRANLFHVLPSRAMQTDALAQYLTLMRWRKIFLITGPTERDKAYADAMRNSARKFGLKITAEKPWTFGPLAKARGDTPTRAEAMVFTRGLDYDLAVVADEEGDWGDYVPFRTVDPRPVAGTQGLIATTWHPTLETWGAAQAQNRFRRLASRLMRPLDYQVWAAVRTVGEAATQTRSTDPATLAAHLVKPEFSLPAYKGVSLTYRPWDHQLRQPIIVVQPKAMVSVAPEQGFIHQRTPLDTLGADMPETACKLP
>NC_012808.1|WP_003601813.1|1848372_1848906_-|DUF3280-domain-containing-protein
MRLRALVPALLPALTLLSTLNGAASAEDAARKAAIFPAEVNDPTLAYGRKPLPADQKRLDLVTDVLRKQLAEKGGLESVDLSPQAEEIRKESPLYKCNDCVAPIAKALGAELAVTAFADKGANQLFSLVVTIAEAETGKVVRRGQVVIRANTDDDWSHATRWIVKNRLLAEPLPGRS
>NC_012808.1|WP_012752621.1|1847616_1848327_-|(5-formylfuran-3-yl)methyl-phosphate-synthase
MSDIVSISSARPRLLVSVRGPDEALTALRAGADLIDAKDPERGALGALPPETVRAIVAGVGGRAVTSAVAGDGTGREIAAAIATIAATGVDFIKIAVGGADDAALAEAAAQAPGRVIGVLFAEDDVAEDGPARLAAAGFVGAMIDTRGKSGTTLTSLMAAPQLAAFVAGCRTHGLMSGLAGSLGLGDIPVLARLDPDYLGFRGGLCRASDRRQALDGARVAQAVEAMRAGPRADAA
>NC_012808.1|WP_003601795.1|1858641_1859001_+|hypothetical-protein
MRIALTLPVALAVLVTAGPALAVSCKDDISTVERRLNSAGAEQVTGKEPPGGVTSSNSPKALDKPPAGAPSDPSTKPTKAGVEEARTLLAKAKEQEKAGQETACQDTMTKVKEKAGALP
>NC_012808.1|WP_003601794.1|1859104_1860661_-|undecaprenyl-phosphate-glucose-phosphotransferase
MSAIDVRDLLKVARENGALTSVPTPLVLYSDENSDSAPSASNPAPTPPKGAWLSPVVLAGCVRLAEFCGLILLGLALHQALLRGVVPLAPRYHAAILAVTLAALGLFQASGSYRISAFRDLPRTAVKLATGWSIAFLMVAAAMVLAKVADHYSRIWLLSYYMAGLGILLGGRAALSAFVRMQMAKGRFDRRTAIVGGGPAAVELIHALEASGDNGIRIIGIFDDRGDDRSSTDVAGYPKLGNVSDLVTYARHAPVDLVVFTLPISAETRILQMLAKLSVLPVDIRLSAHATKLRLRPRAYSYLGGVPLLDVFDKPLADWDVILKGAFDRVVGLLLLLALSPAMIAVALAVKLTSPGPVLFRQKRYGFNNELIEIFKFRSMYVDLCDAGASQLVTKTDARVTPVGRFIRKTSLDELPQLFNVIRGDLSLVGPRPHAVQAKAANTLYDQVVDGYFARHKVKPGITGWAQINGWRGETDTSEKLQRRVEHDLHYIENWSILFDLKILLTTPLALFKTDNAY
>NC_012808.1|WP_003601792.1|1860792_1862052_-|glycosyltransferase-family-4-protein
MASPFAAPLTAALTPQGPTGHAIADLSSRVGTGERHRILHVFRAPVGGLFRHVIDLTRLQAEAGHAVGLVCDASTGGERAERTLADLTPYLALGVTRVPMRRNPHASDLHVLRTVRSQALAVGADVLHGHGAKGGVFARLAPLGRAGRGVIRAYTPHGGSYNYRPGTTLHRVYMAAEQVMARATDLFLFESEYVASRHAAFAGGSPRLERIVHNGIAEAEFAAVETADDPFDLVYVGELREAKGLPVLLRALARLRGQGRELRLLMVGSGPDTESIAAMAENLGLRHAIAFEPPQAIRPVLGRGRVMVVPSLAESLPYVVLEAAAAGQPLVATNVGGIPEIFGAFSSDLVPPGDCEALSAAILHILDEEPSRRQGRARALSNSLRTRFSMNRMATDVLCGYAAAFSAKRTRTASVPATA
>NC_012808.1|WP_003601790.1|1862224_1862803_-|polysaccharide-export-protein
MAMQRRAFLLALPSVLALGGCLRPDFRTVDLDATGTGSIGTRYSLAAGDKLRVIVFGQDNLSNIYAVDGGGRIAMPLIGVVQVGGQTTAQAARLIESKLAAGYVREPHVTVEVDAYRPFYILGEVTTSGQYPYVNGMTVETAVAIAAGFGPRAARDYAVLTREGQGGLINGIVPMSYPVRPGDTIVVKERFF
>NC_012808.1|WP_012752624.1|1863024_1865439_+|LPS-biosynthesis-protein
MPRLRLSTDPSLPPSGGPGGPGDGLAVAQIGGVLRRSWAWIAVPTLVAAIGAGVFVQVVTPRYTGEAKVLLESRDPAFARTAAERTDQTQPIDEQAVASQVQVAMSRDIAREAIRSLKLVGNPEFDPEAEGSSAIRRTLMMLGLVSAPMDRPSEDRILESYLDHLLVYPVGKSRILAVEFRSRDPELAARGANTVADLYLASLEAASVDTARYASTWLGNNIANLRARVAEAEAKVEAFRAKHGLIGTGSSAAAQPLSSQQLSELSSQLSQARTIQADLTARAKLLKDMIKEGRAFEIPDVANNELIRRTVESRMAMRAQLALESRTLLPAHPRIKELTAQVQDLENQIKAAAERVVRTLENDAKIAGARVESLRAAVEGQQDVVAKGNTSEVELRALEREAKSQREQLESYLARYREAAARDAENASPANARVVSRAIVPDLPSFPKKLPIVAFATMLAFLLASAGVIGRHLLVTPAGPGGDRTGDEGEPLVQSTRTDRPRDFYPEPEPPPSRRPVYEPVYGGAYPASAAERFAPALAFAHSLRATATVHHPVFASTAPIGAEAAAQADAAKTDKEGLGVPAKSSASSADLDGLIARLENGTGKGQGEGQGKGPLAGPSKGGCVLVVETPRADGTPGLASNLARVLGPRYQTLLVDVNGVVSGPSEPGLTDLVAGAADFLDVIQPVRGSRLHAVKRGAAPLDVLVEEPQGLAIGLNALSQSYDWVLCRLDARHAEDGAELIPAVGPCMDSIVIASDAPSDDPDLVSLYRLAKETGVARVVVARHGEDADLTPSLEGTSLRLSA
>NC_012808.1|WP_003601785.1|1865992_1866316_-|YbaB/EbfC-family-nucleoid-associated-protein
MRDLMGIMKQAQAMQEKMASVQSELEAVEVSGASGGGAVTVRMTAKGQVLGVSIDPSLMVADEREILEDLIVAACSDARGKAEATAQEKMAELTKGLPLPPGMKLPF
>NC_012808.1|WP_012752625.1|1866405_1868286_-|DNA-polymerase-III-subunit-gamma/tau
MDETHGTLTDEPGLPGMPTPAPVPATTPYRVLARKYRPQTFDDLIGQGAMVRTLGNAFAANRIPQAWMLTGVRGVGKTTTARILARGLNYLRTGQPDTGPTVSMPELGQHCQAIMESRHMDVLEMDAASHTGIDDVRGIIDGIRYSPVSARYKVYIVDEVHMLSEKAFNAFLKTLEEPPPHAKFVFATTEIRKVPVTILSRCQRFDLRRVEADVLAAHLKKICAAEGVEAEDEALAAVTRAAEGSVRDALSLLDQAIAHGAGAVSAAGVRDMLGLADRSRIVDLFEAVMRGDVPAAFAEIRAQYDAGADPAVVLSDLAGFTHLVTRLKLVPGAEADPTLSEAERVRGVAFAGRLPVRALSRAWQILLKALPEVQAAPRPLAAAEMAIVRLAYAADLPTPDEALRQLRADIASSEGNGAARPSLGRDGGSPMASHGSAALQMAPPAPQPSPRPTLAAVPSPVSAAAPQPASRPAPVAPAGPRLGRFEDVVAQAEAARDIALKVALERDVHLVRFEEGRIEFRLAPGGRQSLPTDLARALDAWTGRRWLVALSKEQGAPTLAENTRAAEETRHQNAAAHPLVREVLSRFPGAQIVDVRDKAPETDSADAAANGAGPAAPPPEETDDDA
>NC_012808.1|WP_003607157.1|1868542_1869031_+|hypothetical-protein
MRMTTIPVRLTVLALLASLSVPAGAQDRAGGPAQEGAPKDWQGRYRYEHAAGRTAGGTDIVVTYDLVLLPPDVSDGCVLTVRGFQADETLRCRTRREGQDLALTFDRYGDGRTVNRYGVAVYKPGQPLFTLAKGGALVTRWQGLKPDGQGVADRGAYFKRVR
>NC_012808.1|WP_003607156.1|1869065_1869326_-|PepSY-domain-containing-protein
MSFRPLAAFAIGFALLSGPVLADEKLPPDQQAKVEDILKKEGFTKWKEIELDDGMIEVDDAIDANGKQFDLKLDPKTLEVVKRKAE
>NC_012808.1|WP_012752626.1|1869475_1871014_+|YifB-family-Mg-chelatase-like-AAA-ATPase
MVTRVATVAFEGIEARAVDVQVQIAAGAVAFTIVGLADKAVAESRERVRSALIASGLALPAKRITVNLAPADLPKEGSHYDLPIALAVMGAIGALPADALGGYCVLGELALDGSITAVAGVLPAAMAANGRGLGLICPAATGPEAAWAAGDMDVLAPRSLIQLANHFKGSQVMARPQPAVAAPAGPMSDLRDIKGQEGAKRALEIAAAGGHNLLMNGPPGAGKSMLAARLPSILPPLGPRELLEVSMIQSVAGELKGGALSNRRPFRQPHHSASMAALVGGGLNARPGEASLAHGGVLFLDELPEFTPQVLDSLRQPMETGEIMIARANHRTTYPARFQLVAAMNPCRCGMALEPGYACRRGPNERCVAQYGARISGPLLDRIDLRIEVAAVTAADLIVPPPAEGSAEAAARVAAARALQSARYAALGLPAATTNATCPATVIESAAAPDAEGAALIRHAAETMRLSARGFHRTLRVALTLADLDGEAQVRRLHLAEALSYRARGEQPAAAA

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Crispr_ID: NC_012808_3

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_012808_3

2521865-2522136

Orphan

Consensus_repeat	Method
GGCAACAACGTCGTGCTCGGCGG	CRISPRCasFinder

4 spacers

The CRISPR arrays of NC_012808_3

>merge|NC_012808|3|2521865-2522136|CRISPRCasFinder
GGCAACAACGTCGTGCTCGGCGGCACGGGCCGCGACACGATCACCATCGGCGACGGCAACAACGTCGTGCTCGGCGATAGCGGCCAAGCCGATTTCGAGGCCGGCATCATCGTCGAGATCGCCAGCATCAGCCCGGAGGTCGGCGACAACGATACGATCGCGCTCGGCAGCGGCCGCAACACCGTCATCGGCGGTGCCGGCAGCGACAGCATCACTGCGGGCCTCCGCAACGGCGTGAAGGCCGGCACCGGCACCAACGTCATCCTCGGCGA

>NC_012808|3|3|2521865-2522136|CRISPRCasFinder
GGCAACAACGTCGTGCTCGGCGG	CACGGGCCGCGACACGATCACCATCGGCGAC
GGCAACAACGTCGTGCTCGGCGA	TAGCGGCCAAGCCGATTTCGAGGCC
GGCATCATCGTCGAGATCGCCAG	CATCAGCCCGGAGGTCGGCGACAACGATACGATCGCGCTCGGCAGC
GGCCGCAACACCGTCATCGGCGG	TGCCGGCAGCGACAGCATCACTGCGGGCCTCCGCAACGGCGTGAAGGCCGGCACC
GGCACCAACGTCATCCTCGGCGA

Protein	Signature genes	Signature genes Name	Protein_function
NC_012808.1\|WP_012752851.1\|2480045_2482433_+\|tryptophan-7-halogenase	unknown	unknown	gnl\|CDD\|368139
NC_012808.1\|WP_003601237.1\|2486251_2487052_+\|SapC-family-protein	unknown	unknown	gnl\|CDD\|377801
NC_012808.1\|WP_003600397.1\|2539343_2540783_-\|multicopper-oxidase-family-protein	unknown	unknown	gnl\|CDD\|225043
NC_012808.1\|WP_003600395.1\|2542719_2543346_+\|ATP-dependent-Clp-protease-proteolytic-subunit	unknown	unknown	gnl\|CDD\|178955
NC_012808.1\|WP_003601243.1\|2483322_2484255_+\|radical-SAM-protein	unknown	unknown	gnl\|CDD\|223609
NC_012808.1\|WP_003606160.1\|2477624_2477921_-\|DUF3467-domain-containing-protein	unknown	unknown	gnl\|CDD\|371814
NC_012808.1\|WP_012752852.1\|2482429_2483305_+\|hypothetical-protein	unknown	unknown	unknown
NC_012808.1\|WP_012752850.1\|2479356_2480016_+\|uridine-kinase	unknown	unknown	gnl\|CDD\|181310
NC_012808.1\|WP_003600394.1\|2543597_2544869_+\|ATP-dependent-Clp-protease-ATP-binding-subunit-ClpX	unknown	unknown	gnl\|CDD\|235422
NC_012808.1\|WP_003600403.1\|2534897_2535713_+\|2OG-Fe(II)-oxygenase	unknown	unknown	gnl\|CDD\|379309
NC_012808.1\|WP_012253842.1\|2541151_2542588_+\|trigger-factor	unknown	unknown	gnl\|CDD\|234956
NC_012808.1\|WP_003601241.1\|2484386_2485316_-\|helix-turn-helix-domain-containing-protein	unknown	unknown	gnl\|CDD\|236612
NC_012808.1\|WP_003600400.1\|2536647_2538027_+\|B12-binding-domain-containing-radical-SAM-protein	unknown	unknown	gnl\|CDD\|223963
NC_012808.1\|WP_012752849.1\|2475648_2477535_-\|efflux-RND-transporter-periplasmic-adaptor-subunit	unknown	unknown	gnl\|CDD\|273776
NC_012808.1\|WP_003600393.1\|2545136_2547557_+\|endopeptidase-La	unknown	unknown	gnl\|CDD\|223542
NC_012808.1\|WP_003606161.1\|2478307_2479360_+\|methyltransferase-domain-containing-protein	unknown	unknown	gnl\|CDD\|366359
NC_012808.1\|WP_012752855.1\|2548152_2548389_-\|hypothetical-protein	unknown	unknown	unknown
NC_012808.1\|WP_003601240.1\|2485952_2486255_+\|hypothetical-protein	unknown	unknown	unknown
NC_012808.1\|WP_003600402.1\|2535717_2536509_+\|methyltransferase-domain-containing-protein	unknown	unknown	gnl\|CDD\|225136
NC_012808.1\|WP_003600398.1\|2538023_2539337_+\|B12-binding-domain-containing-radical-SAM-protein	unknown	unknown	gnl\|CDD\|223963

Protein	Function_ID	Function_description	E-value
NC_012808.1\|WP_012752851.1\|2480045_2482433_+\|tryptophan-7-halogenase	gnl\|CDD\|368139	pfam04820, Trp_halogenase, Tryptophan halogenase. Tryptophan halogenase catalyzes the chlorination of tryptophan to form 7-chlorotryptophan. This is the first step in the biosynthesis of pyrrolnitrin, an antibiotic with broad-spectrum anti-fungal activity. Tryptophan halogenase is NADH-dependent.	1.73763e-80
NC_012808.1\|WP_003601237.1\|2486251_2487052_+\|SapC-family-protein	gnl\|CDD\|377801	pfam07277, SapC, SapC. This family contains a number of bacterial SapC proteins approximately 250 residues long. In Campylobacter fetus, SapC forms part of a paracrystalline surface layer (S-layer) that confers serum resistance.	2.50941e-91
NC_012808.1\|WP_003600395.1\|2542719_2543346_+\|ATP-dependent-Clp-protease-proteolytic-subunit	gnl\|CDD\|178955	PRK00277, clpP, ATP-dependent Clp protease proteolytic subunit; Reviewed.	2.92817e-146
NC_012808.1\|WP_003601243.1\|2483322_2484255_+\|radical-SAM-protein	gnl\|CDD\|223609	COG0535, COG0535, Predicted Fe-S oxidoreductases [General function prediction only].	1.11606e-23
NC_012808.1\|WP_003606160.1\|2477624_2477921_-\|DUF3467-domain-containing-protein	gnl\|CDD\|371814	pfam11950, DUF3467, Protein of unknown function (DUF3467). This family of proteins are functionally uncharacterized. This protein is found in bacteria, archaea and viruses. Proteins in this family are typically between 101 to 118 amino acids in length.	2.09627e-15
NC_012808.1\|WP_012752850.1\|2479356_2480016_+\|uridine-kinase	gnl\|CDD\|181310	PRK08233, PRK08233, hypothetical protein; Provisional.	2.08974e-17
NC_012808.1\|WP_003600394.1\|2543597_2544869_+\|ATP-dependent-Clp-protease-ATP-binding-subunit-ClpX	gnl\|CDD\|235422	PRK05342, clpX, ATP-dependent Clp protease ATP-binding subunit ClpX.	0
NC_012808.1\|WP_003600403.1\|2534897_2535713_+\|2OG-Fe(II)-oxygenase	gnl\|CDD\|379309	pfam13640, 2OG-FeII_Oxy_3, 2OG-Fe(II) oxygenase superfamily. This family contains members of the 2-oxoglutarate (2OG) and Fe(II)-dependent oxygenase superfamily.	6.83888e-05
NC_012808.1\|WP_012253842.1\|2541151_2542588_+\|trigger-factor	gnl\|CDD\|234956	PRK01490, tig, trigger factor; Provisional.	4.59294e-156
NC_012808.1\|WP_003601241.1\|2484386_2485316_-\|helix-turn-helix-domain-containing-protein	gnl\|CDD\|236612	PRK09685, PRK09685, DNA-binding transcriptional activator FeaR; Provisional.	6.69207e-20
NC_012808.1\|WP_003600400.1\|2536647_2538027_+\|B12-binding-domain-containing-radical-SAM-protein	gnl\|CDD\|223963	COG1032, COG1032, Fe-S oxidoreductase [Energy production and conversion].	1.47749e-20
NC_012808.1\|WP_012752849.1\|2475648_2477535_-\|efflux-RND-transporter-periplasmic-adaptor-subunit	gnl\|CDD\|273776	TIGR01730, COG0845:_Membrane-fusion_protein, RND family efflux transporter, MFP subunit. This model represents the MFP (membrane fusion protein) component of the RND family of transporters. RND refers to Resistance, Nodulation, and cell Division. It is, in part, a subfamily of pfam00529 (Pfam release 7.5) but hits substantial numbers of proteins missed by that model. The related HlyD secretion protein, for which pfam00529 is named, is outside the scope of this model. Attributed functions imply outward transport. These functions include nodulation, acriflavin resistance, heavy metal efflux, and multidrug resistance proteins. Most members of this family are found in Gram-negative bacteria. The proposed function of MFP proteins is to bring the inner and outer membranes together and enable transport to the outside of the outer membrane. Note, however, that a few members of this family are found in Gram-positive bacteria, where there is no outer membrane. [Transport and binding proteins, Unknown substrate].	9.60247e-25
NC_012808.1\|WP_003600393.1\|2545136_2547557_+\|endopeptidase-La	gnl\|CDD\|223542	COG0466, Lon, ATP-dependent Lon protease, bacterial type [Posttranslational modification, protein turnover, chaperones].	0
NC_012808.1\|WP_003606161.1\|2478307_2479360_+\|methyltransferase-domain-containing-protein	gnl\|CDD\|366359	pfam00891, Methyltransf_2, O-methyltransferase. This family includes a range of O-methyltransferases. These enzymes utilize S-adenosyl methionine.	4.42095e-23
NC_012808.1\|WP_003600397.1\|2539343_2540783_-\|multicopper-oxidase-family-protein	gnl\|CDD\|225043	COG2132, SufI, Putative multicopper oxidases [Secondary metabolites biosynthesis, transport, and catabolism].	3.62858e-54
NC_012808.1\|WP_003600402.1\|2535717_2536509_+\|methyltransferase-domain-containing-protein	gnl\|CDD\|225136	COG2226, UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis [Coenzyme metabolism].	3.20546e-17
NC_012808.1\|WP_003600398.1\|2538023_2539337_+\|B12-binding-domain-containing-radical-SAM-protein	gnl\|CDD\|223963	COG1032, COG1032, Fe-S oxidoreductase [Energy production and conversion].	3.20592e-26

>NC_012808.1|WP_003601237.1|2486251_2487052_+|SapC-family-protein
MSKQLLIYERAVPVTRQRHGSWSVKAGASFDFARGVNSVPLMVAEFPNSAAEYAIVFGGAADEIIPVALLGIRDNENLYVSESGSWSGSYVPAFLRRYPFVFSSDNANDADATFTLCVDEDFSGCNDEGRGERLFDADGERTQYLQNVLGFLQAYQVQFQRTKLFVKRLQEFGLLEPMQAQFTLRSGQRSTLSGFSVVSRDRLKALSAEQLAELMQADEMELIYLHLASLRNLAPIAERIGAPAESAQADETAPASPADFETSGNA
>NC_012808.1|WP_003601240.1|2485952_2486255_+|hypothetical-protein
MAVYRSAKPSFDIVSNRVQPMIIFAPTPITMASETRAFENGPPGLILSGEAVAARAASSASETLDQSKKWNHPSAAVGGTDMQQEAKMRESHKRRQMGSE
>NC_012808.1|WP_003601241.1|2484386_2485316_-|helix-turn-helix-domain-containing-protein
MVGPLFEPRAFHPGQQSPTGSASGAIIGDIMVARVVFGAQSYRRDRDLIARTPDHILFHLYNVGGFSGLISGQQTTIWSSQVAIIDLAQEIDTLAASSDTVALIVPRALLPGLADNPLPPRLDAGRNRLLAAHLIALRERSTLIEEPDVEEVVTQTLDFLRALLDPSRAEETAATPTLATCHLTLAEQTIRTHLASPDLSPEMIANEIGVSRATLYRMFAPYGGIMRSVQERRLLAVRAALSDPLETRRLSRLATDFGFRGKVHFSRSFRAQFGITASEFRAEQVALAQRDARSDLGVLHDWWPRLGNR
>NC_012808.1|WP_003601243.1|2483322_2484255_+|radical-SAM-protein
MGRYDHAAYVSLTMEFRCNLKCVHCMIEGTMDRLAPESDAHFEEILALNARERRWSGLILTGSEITLRRDLPELARRARASGFAHVRIQTHGMHLGQPSYCRRLVEAGVDEFFVSIAGSDAASHDALTLVPGSFERALRGLETLDAMEGVETLTNTVVTERSYRLLPDLVTRLAHLQRLTQMEFWVYFPMSERDEKGLVARHADVLPYLREAVLRARALGRAVEVKNFPECLLGDLGNALVNGQPELHIDPDFWREFERNGFYQCAHRETCSSRECLGLNTAYVAKFGLEADLVHPLPAPRRQAWSRAPA
>NC_012808.1|WP_012752852.1|2482429_2483305_+|hypothetical-protein
MTGLDPARLELSAPGDRYADYCLWDYEPVGPTAGRLRQASLLWHSLACAGADPRLFAICDALRDGLGPGRSVWGAKLRDGVTTWEFYFYDYARLDRTVSIERVLAILAPFAPCDLRYAGGRPYFMFSLDFDDALARGERSLDRLNIYVGNPGSSVSSGLSYGLTADGLVFDNLYSFFDAARERDAIAAKAACSAHFDLPGLDLDAMLWPELMRCGVVVVANKRLCDGVYFSRVGIDGLIAFLDRLAYPPAIRDFVRSERRRLSHLLFDVGIDYAVIDGRLTVTKSAYYGLL
>NC_012808.1|WP_012752851.1|2480045_2482433_+|tryptophan-7-halogenase
MFRSERSAPARLVVAGGGPAGWMAALYLKRVLRRAGWTVTLVGSAPAAGASAALATRPAFTRFLKGFGIDEAIFMRRCAATYRLASRYDDWFAEGQGHWHPFGACGPRIAGRDLFHYWMKLRGEGAEDEAGSYADYAPQALMAAEGRGPRPLADRSSLTESGDYGYHLDRKALVRFLRELALSEGVRGVTGRVREIERNLYGDVGALILDGGQTIEGDIFLDCTGAAAQLIGTALGEAWVAGSGPGDRVARLSLPRSPEVPPFTAYRGRAEGWTASLPLADRTEHLFVYDSRTTPPDAAAATLRRAFDGQAGIVDAELRHGRRASPWQRNVVAMGAAARAVEPLLGFDLDLVLAGLETFLAYLPRQGEGGDVLRRAYAARLNRFHDDAAEAVAAHYVLGRRSEPFWAAARAVMIPDRLADRLDLYELAGHVALSEEGPFSEGDHYLLFSGADFLPRRPFAPVDVADGREIARLLASIRAQSAQIAGAMAPHVRLMDALHGEAPVAAPAVRIAAASAPAGPAALRRTPEGARLADLVAGLAQPFGYERSVKASPAGLQTDRFLMSLHRASLGLTPEATLDRLAAGLGLPERERAEAAGLIGGADILHLGYEDGPSGALYKLYIEWSSRTDAAWTGVDETGAEPMLVHRAYKWKPGGAHPPVVTLYHWPRVRGPEEIQARLNRMAGAWGPAGAPARDTAHAILRLAQERGRGAVHYLEAREEPGLRLSYDLNLYACGLSVADAEPLLGQAFVDLGVPREAAAMVLRERLQETLGHVAGGVGRDGQPFVTVYSGVAGG
>NC_012808.1|WP_012752850.1|2479356_2480016_+|uridine-kinase
MSAPFVLAVSGPPGSGKTTLSHALSERFGGAPVLAYDAYEEITGWPPERVAAWLAGGAPLDAVPVPGLAEDLARLRRGEPVPDRERGGTLRLSRRAARPVIVLDTLLGRAHPGTGAQIDHLVWLDLPLDVALARKLRSFTGAARRDPTAAPGLLEALDAYLGRYDALLHPTYALQRERVRPAADQILGAGTLAAHLDAVQSAIQSTLHATLTAVPTPTA
>NC_012808.1|WP_003606161.1|2478307_2479360_+|methyltransferase-domain-containing-protein
MSAPELPGPEFPRVDRFLESEAAAHALSFALTSGLIDRLARRADTAISGLADEFRLERPQLACLTGLLVGAGIAAEPAPGRIGLSEAFRAVLPCRDLIEAKLAFAAAASEDLRRHFPAFVADLPAFMAASRTFELFRYDRCFEITPDNLDATRRWVAYTTCLTRYEAGPGLDRIEPGRHRRLLDLGGNSGEFAAQACRRAPDLTATVFDLPVVCALGRENLADRPEGARVAFQAGDMRRDPLPEGHDLVTFKSVLHDWPAGEARALLERAARALAPGGRLAIYERAPMALRERPLGYVQSADLVFQPFFRDADLYTETLAALGFVDCSVRCLALETPFHLIEARKPGGAR
>NC_012808.1|WP_003606160.1|2477624_2477921_-|DUF3467-domain-containing-protein
MSESSKPGAADQVRAIEWREDSMSTQFANVVNVQGTREQVDLFFGTNRTWNLAETESVVVDLSNRVILTPLAAKRLHSVLGGVLTEYENRHGRLDLDA
>NC_012808.1|WP_012752849.1|2475648_2477535_-|efflux-RND-transporter-periplasmic-adaptor-subunit
MSERLAVEGASAASPAARLSLLEPALWQVLRTSQTLQAAAEAWLTLQAPMLGAPRACVLLPGTSVGLAPLAVFPAQSECEAGLRETAEAAFRENRPVVQAMAEAGPHPGAAPHGSGAWIALPLVLDEACFAVTAFALDSLDKDELRAAIRQVQWGSAWLVAKQAELIGRGERRTLARSRSVLDLLAGVLEQSRFSAACTAAVTDLAIAFSCQRAAIGFVRRGSARIAAISHSAQFGREMNLVRRLGACMNEAIDQRSLILFPPPENEATVTTAHADLARLQYGGRVLTVPMLVDDRFVGAITLERPADQPFSLEIVEQVSACAAAIGPVLEDKRQNDRWLVLKATDAVMNGARLVFGPNHTGLKLGLAAVLAVVLALSVIKIDYRVTADARVEGLVRRSVVASYDGYLKTAGHRAGDTVRKGDLLAALEDRDLALERLRWVTERQQRTYEYDKALATRQPATINVVKSQIDQADAQIRLLDEQIARSKFTAPFDGLIVSGDLSQSIGGAISRGQVLFEIAPLDSYRVVLSVDERLIADLREGQTGHVLATSLPDQPQVLTIQTITPVAEAKNGRNLFRVEGRIEDGATRLRPGMEGIAKVDVDRRLLAWVWARPIVDWVRLALWHWWP
>NC_012808.1|WP_003600403.1|2534897_2535713_+|2OG-Fe(II)-oxygenase
MPFLQTISIDAAEASAHADALTQLREDAFQAVVIRNVLTPAECASIVTDLAANRQGFPTTSFPAPFRSHFYGMNLNLAEPDLRAYFDMAPGFTRSLGELMAPWGGFETRILALLSRLDGGRPYGPPALHDGRTYMATTLRSHHEGGYIPPHFDNEQKNRPSYRHLESVVEGDIFSFVLTLSKAERGGMLEVFDAKAEAWSGRFQNRDRAREKPDLARFARHAFDVEAGTIVLLRSGRFLHQVTPVEGARLRWTACSFMARSRTGDAVHCWG
>NC_012808.1|WP_003600402.1|2535717_2536509_+|methyltransferase-domain-containing-protein
MARIPVYFDAFLAAVAEGAAIEHVHLGHWDEPGAIGPARARAGFVEAQERLSAALVAWLDLAPGHRVLDVGCGFGGTLRALRRSDPEVEVIGLNLDPRQLAVGLRQDDRPRNAAWVAGDACRLPFAEAAFDRLLCVEAAFHFASRRAFFGEAQRVLTREGVLVMSDIVLTRPSLPPERVGLFADGLEAAFGPWPDKWAGLDAIRRDAEAAGFTLRVTDATANTEPSYHTIASDRRGQPTGGDVLRELHRLGCLHYLYCRLDKR
>NC_012808.1|WP_003600400.1|2536647_2538027_+|B12-binding-domain-containing-radical-SAM-protein
MLEPSSPTHRRIALVCMTPRPDAQELGELLLPSYGIRRIHAALLGDPDLADASVRLFDRRTADIEAYVADILDFEPDLVGFSIYVWSAPAMIAVARALRARRPSLAIVFGGPSARSAFFDLEPYRPAHAYLDAVVEGDGEEIICEIARLPQLDRAAWERVRGLTLPTATGWLRTERRPPITALDRIASPYAHGLMPQGGVAYLESFRGCPLSCRFCEWGTKENSKASFSADYIARELDAFRTLEAPAVFLLDAGLNLNIGAFRNLRLANQRSGFLKETLLWAEIYPSIVRDEHLAFIEEIGTAYLGVGMQSMDPAVLRLHDRPSDSPRFEAAVRALARVTNIELQIIAVLPGDTPEGFFRTLDYALSLPASVRVYHCLVLPDALLTRSRPEWNVRFDPHALTMRSCEGWSEDAVARTRAELRRRALAAGGKAGEFWWAFPRQPERVTQARASWRQAAAR
>NC_012808.1|WP_003600398.1|2538023_2539337_+|B12-binding-domain-containing-radical-SAM-protein
MKAARSGLRIALVAQYPERDPAMPSFVPNLGLRMVEATLRAAALPGLVCRVWDLNGGDPERVAREITAFDPDIVGFSAYLWSLPFLCRVAALIKQDDPARLVVFGGPSARPVMFARPPFAKAADDIDVLVINEGEETFLEIVSLEQRTPAALGTLRGVAVRDGAGWRETPARPLANLDSLASPYALNLVQHGGLGVLQTYRGCPFTCSFCEWGTMESPKRVRAVDHLTQEFEAIAGHDVYAALLVDAGLNLNRNAFLNLRRAAEESGFFERHGLICEVYPAAVRQEHLDFLATVRNAYVGIGLQSFDNAVLAHVDRTYDERRFDETFAKLDAVASLAVEIILGLPGDNPETFRRNFERARRLPCALRVYHCVVLPSGLMVRSPPEHRLDYDPVSLKMTSCTGWSEAALAAECRFLNRQASLQGGRSGEFFWTFPPPR
>NC_012808.1|WP_003600397.1|2539343_2540783_-|multicopper-oxidase-family-protein
MRNPDPTAQPAPGSFSRRDLLAGSAALALMPRTAAAQAPAGKAPPSEPKSIKAAPATLRLKPEPAPETAVWRLGEAEAPILRVKLGEAIRLRVENGTDKPLSLHWHGVRIVNAMDGVGGVTQEPIKPGASFTYDFTPPDAGSFLIRALVVGGSSEPSGRGIAGMLIVDEPSPPPVDADLALLVQDWRLDEAGALQPFGQVAFAAAAGRLGSVVTLNGRPIPLALDARPGSRLRLRLANACNARSLRIRFDGLKAYVAAVDGQPTDTFEPLKATLPFAPGTRYDLLLDLPAQAGPAGTITALVGQGLPLATLTAVGEPVAQSGRAAIGSIPENKRLPAEIRLQSALRRELVLTGGVRPDKAKPGAETPYSGDPAKIWQINGASGTAGAAPLFSVKRGGVVVLSIRNDTGFIQSLHLHGHVFRLLHQLDDGWEPYWLDTVQIPEGKSAQIAFVADNPGRWLLSATVLERFDTGLWTSFEVS
>NC_012808.1|WP_012253842.1|2541151_2542588_+|trigger-factor
MQVTETTSEGLKREFQVLLPANELEDRLNTELSNIKGKVQIKGFRPGKVPVAHLRKVYGKSVMADVLQNAVNEANQQIVTDKGLRLALEPQIEFPKDEEQTIIERALDAKGDLAFKVKLEVLPSFELADLSDVSIKKLVLKPSDEEVNETLERMAKDSRSFEPREEGAEAQSGDRVTIDFVGRIDGTEFEGGKGEDVDLELGSNTFIPGFEDQLVGAKVGDSRLVKVAFPADYQAEQLAGKDAEFDVTVKAVAAPGETKIDDELAKRFGMDDLEKLKEAVSKAVGSDYEAQSRRKLKKELLDALDGKYAFDLPPSLVHQEFAAVWAQVEQDLKTRGKTFEDEGTTEEASQAEYRKIAERRVRLGLVLAQVGETADIKVSDDEVNQALFARIRQFPGQEKQVYDFYRNNPQALAELRAPLFEEKVVDHVLGQVQVVEEPVSKEALFAEDDEADAVTGGAATDEKPSESNNEAAADKAAG
>NC_012808.1|WP_003600395.1|2542719_2543346_+|ATP-dependent-Clp-protease-proteolytic-subunit
MRDPVDYFHNSLVPMVVEQSSRGERAFDIYSRLLRERIIFLTGPVEDQGASLIVAQLLFLEAENPKKEISFYINSPGGVVTSGLSIYDTMQFIRCPVTTLCVGQAASMGSLLLAAGEAGHRFALPNARIMVHQPSGGFQGQATDILIHAREIEALKKRLNEIYVKHTGREYETIHQALERDNFMTADAAKEFGLIDDILHKRPEPAAA
>NC_012808.1|WP_003600394.1|2543597_2544869_+|ATP-dependent-Clp-protease-ATP-binding-subunit-ClpX
MSKTGGNDSKSTLYCSFCGKSQHEVRKLIAGPTVFICDECVELCMDIIREESKSSLVKSRDGVPTPKEIRRVLDDYVIGQDFAKKVLSVAVHNHYKRLAHATKHNDVELAKSNIMLIGPTGSGKTLLAQTLARILDVPFTMADATTLTEAGYVGEDVENIILKLLQASDYNVERAQRGIVYIDEIDKISRKSDNPSITRDVSGEGVQQALLKIMEGTVASVPPQGGRKHPQQEFLQVDTTNILFICGGAFAGLERIISQRGKGTSIGFGASVQAPDDRRTGEVFRSVEPEDLLKFGLIPEFVGRLPVLATLEDLDEEALKKILQEPKNALVKQYQRLFEMENVELTFQDEALSLVARKAIERKTGARGLRSILETILLDTMYDLPGLESVEQVVIGPEVVEGKSRPLFIHGDRNKEAPASVSA
>NC_012808.1|WP_003600393.1|2545136_2547557_+|endopeptidase-La
MTQSKSRQPVVPGSTGSYAVLPLRDIVVFPHMIVPLFVGREKSIRALEEAVRSDRHILLATQINASDDDPATDAIYTIGTLASVLQLLKLPDGTVKVLVEGAGRAQIESFVRSDEYYEAQALTLTDDLGDRVEAEALARSVISEFENYVKLNKKISPEVVSAVTQIDEPSKLADTVGSHLAVKIADKQAILEIPTVAQRLERVLSLMESEISVLQVEKRIRTRVKRQMEKTQREYYLNEQMKAIQKELGDEDGRDELAELEDKIEKTKLTKEAREKATAELKKLRQMSPMSAEATVVRNYLDWMLGIPWGKRSKIKKDLLGAQQVLDSDHFGLDKVKDRIVEYLAVQQRANKLTGPILCLVGPPGVGKTSLGKSIAKATGREFVRMSLGGVRDEAEIRGHRRTYIGSMPGKIVQSMRKAKTSNPLILLDEIDKMGMDFRGDPSAALLEVLDPEQNATFNDHYLEVDYDLSNVMFVTTANTLNIPGPLMDRMEVIRIAGYTEEEKLQIARRHLIPEAVKKHGLTPDEWSITDDGLMMLIRRYTREAGVRNLEREISNLIRKAVKEILITKVKQVEANPETLPEFLGPPKFRYGEIDADDQVGVVTGLAWTEVGGELLTIEGVMMPGKGKMTVTGNLRDVMKESISAAASYVRSRAIDFGIEPPLFERRDIHVHVPEGATPKDGPSAGIAMATAIISTLTGIPVRRDVAMTGEVTLRGRVLPIGGLKEKLLAALRGGIKTVMIPEENAKDIAEVPDSVKNGLEIIPVSRMDQVLQHALVRQPEPIEWDEPLPAKTPKRDEDGAAVIAH
>NC_012808.1|WP_012752855.1|2548152_2548389_-|hypothetical-protein
MTMCGKETVQYGRPRRRRHEAWIYRRSMRIVPLLLRGKEKTDRAEDARLQPSDNDNAAGRDASNRYEPRDRQASLASR

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Crispr_ID: NC_012808_4

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_012808_4

4675268-4675354

Orphan

Consensus_repeat	Method
CGGCTTTCGGGAAAAAGATGATGC	CRISPRCasFinder

1 spacers

The CRISPR arrays of NC_012808_4

>merge|NC_012808|4|4675268-4675354|CRISPRCasFinder
CGGCTTTCGGGAAAAAGATGATGCAAGAACGAAAGCGAAGAGCATCATCCTGAAAGGTGGCCAGCGGCTTTCGGAAAAAGATGATGC

>NC_012808|4|4|4675268-4675354|CRISPRCasFinder
CGGCTTTCGGGAAAAAGATGATGC	AAGAACGAAAGCGAAGAGCATCATCCTGAAAGGTGGCCA
GCGGCTTTCGGAAAAAGATGATGC

Protein	Signature genes	Signature genes Name	Protein_function
NC_012808.1\|WP_003599059.1\|4681486_4681951_+\|DUF2721-domain-containing-protein	unknown	unknown	gnl\|CDD\|378544
NC_012808.1\|WP_003599063.1\|4681141_4681471_+\|lipid-A-disaccharide-synthase-N-terminal-domain-containing-protein	unknown	unknown	gnl\|CDD\|226461
NC_012808.1\|WP_003599086.1\|4670568_4670778_+\|cold-shock-protein	unknown	unknown	gnl\|CDD\|224197
NC_012808.1\|WP_003599066.1\|4678585_4680382_+\|glycosyltransferase-family-39-protein	unknown	unknown	gnl\|CDD\|224720
NC_012808.1\|WP_012255296.1\|4671427_4671625_+\|hypothetical-protein	unknown	unknown	unknown
NC_012808.1\|WP_003599081.1\|4671691_4672033_-\|hypothetical-protein	unknown	unknown	unknown
NC_012808.1\|WP_003599091.1\|4666091_4666388_+\|succinate-dehydrogenase-assembly-factor-2	unknown	unknown	gnl\|CDD\|225489
NC_012808.1\|WP_131473064.1\|4663416_4663641_-\|hypothetical-protein	unknown	unknown	unknown
NC_012808.1\|WP_003599088.1\|4666601_4670192_+\|transcription-repair-coupling-factor	unknown	unknown	gnl\|CDD\|224118
NC_012808.1\|WP_003599065.1\|4680378_4681137_+\|glycosyltransferase-family-2-protein	unknown	unknown	gnl\|CDD\|133022
NC_012808.1\|WP_043766524.1\|4672291_4673692_-\|acyl--CoA-ligase	unknown	unknown	gnl\|CDD\|223395
NC_012808.1\|WP_003599070.1\|4676365_4678003_-\|acyl-CoA-synthetase	unknown	unknown	gnl\|CDD\|236169
NC_012808.1\|WP_003599084.1\|4670880_4671249_+\|hypothetical-protein	unknown	unknown	unknown
NC_012808.1\|WP_015857406.1\|4663710_4665900_-\|ATP-dependent-DNA-helicase-RecG	unknown	unknown	gnl\|CDD\|236794
NC_012808.1\|WP_012255300.1\|4675443_4675806_+\|response-regulator	unknown	unknown	gnl\|CDD\|381145
NC_012808.1\|WP_003599073.1\|4676094_4676322_-\|hypothetical-protein	unknown	unknown	unknown
NC_012808.1\|WP_015857409.1\|4673989_4675243_+\|ATP-binding-protein	unknown	unknown	gnl\|CDD\|237425
NC_012808.1\|WP_003599068.1\|4678141_4678336_-\|hypothetical-protein	unknown	unknown	unknown
NC_012808.1\|WP_003599075.1\|4675819_4676116_-\|type-II-toxin-antitoxin-system-RelE/ParE-family-toxin	unknown	unknown	gnl\|CDD\|368240
NC_012808.1\|WP_003599057.1\|4681954_4683466_-\|NAD(P)/FAD-dependent-oxidoreductase	unknown	unknown	gnl\|CDD\|224983

Protein	Function_ID	Function_description	E-value
NC_012808.1\|WP_003599059.1\|4681486_4681951_+\|DUF2721-domain-containing-protein	gnl\|CDD\|378544	pfam11026, DUF2721, Protein of unknown function (DUF2721). This family is conserved in bacteria. The function is not known.	6.68059e-22
NC_012808.1\|WP_003599063.1\|4681141_4681471_+\|lipid-A-disaccharide-synthase-N-terminal-domain-containing-protein	gnl\|CDD\|226461	COG3952, COG3952, Predicted membrane protein [Function unknown].	5.18556e-27
NC_012808.1\|WP_003599086.1\|4670568_4670778_+\|cold-shock-protein	gnl\|CDD\|224197	COG1278, CspC, Cold shock proteins [Transcription].	4.06042e-32
NC_012808.1\|WP_003599066.1\|4678585_4680382_+\|glycosyltransferase-family-39-protein	gnl\|CDD\|224720	COG1807, ArnT, 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family [Cell envelope biogenesis, outer membrane].	4.82273e-45
NC_012808.1\|WP_003599075.1\|4675819_4676116_-\|type-II-toxin-antitoxin-system-RelE/ParE-family-toxin	gnl\|CDD\|368240	pfam05016, ParE_toxin, ParE toxin of type II toxin-antitoxin system, parDE. ParE is the toxin family of a type II toxin-antitoxin family. It is toxic towards DNA gyrase, but is neutralized by the antitoxin ParD. The family also encompasses RelE/ParE described in.	7.14712e-07
NC_012808.1\|WP_003599091.1\|4666091_4666388_+\|succinate-dehydrogenase-assembly-factor-2	gnl\|CDD\|225489	COG2938, COG2938, Uncharacterized conserved protein [Function unknown].	1.78398e-27
NC_012808.1\|WP_003599088.1\|4666601_4670192_+\|transcription-repair-coupling-factor	gnl\|CDD\|224118	COG1197, Mfd, Transcription-repair coupling factor (superfamily II helicase) [DNA replication, recombination, and repair / Transcription].	0
NC_012808.1\|WP_003599065.1\|4680378_4681137_+\|glycosyltransferase-family-2-protein	gnl\|CDD\|133022	cd04179, DPM_DPG-synthase_like, DPM_DPG-synthase_like is a member of the Glycosyltransferase 2 superfamily. DPM1 is the catalytic subunit of eukaryotic dolichol-phosphate mannose (DPM) synthase. DPM synthase is required for synthesis of the glycosylphosphatidylinositol (GPI) anchor, N-glycan precursor, protein O-mannose, and C-mannose. In higher eukaryotes,the enzyme has three subunits, DPM1, DPM2 and DPM3. DPM is synthesized from dolichol phosphate and GDP-Man on the cytosolic surface of the ER membrane by DPM synthase and then is flipped onto the luminal side and used as a donor substrate. In lower eukaryotes, such as Saccharomyces cerevisiae and Trypanosoma brucei, DPM synthase consists of a single component (Dpm1p and TbDpm1, respectively) that possesses one predicted transmembrane region near the C terminus for anchoring to the ER membrane. In contrast, the Dpm1 homologues of higher eukaryotes, namely fission yeast, fungi, and animals, have no transmembrane region, suggesting the existence of adapter molecules for membrane anchoring. This family also includes bacteria and archaea DPM1_like enzymes. However, the enzyme structure and mechanism of function are not well understood. The UDP-glucose:dolichyl-phosphate glucosyltransferase (DPG_synthase) is a transmembrane-bound enzyme of the endoplasmic reticulum involved in protein N-linked glycosylation. This enzyme catalyzes the transfer of glucose from UDP-glucose to dolichyl phosphate. This protein family belongs to Glycosyltransferase 2 superfamily.	2.08491e-49
NC_012808.1\|WP_043766524.1\|4672291_4673692_-\|acyl--CoA-ligase	gnl\|CDD\|223395	COG0318, CaiC, Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II [Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism].	7.65111e-21
NC_012808.1\|WP_003599070.1\|4676365_4678003_-\|acyl-CoA-synthetase	gnl\|CDD\|236169	PRK08162, PRK08162, acyl-CoA synthetase; Validated.	0
NC_012808.1\|WP_015857406.1\|4663710_4665900_-\|ATP-dependent-DNA-helicase-RecG	gnl\|CDD\|236794	PRK10917, PRK10917, ATP-dependent DNA helicase RecG; Provisional.	0
NC_012808.1\|WP_012255300.1\|4675443_4675806_+\|response-regulator	gnl\|CDD\|381145	cd18161, REC_hyHK_blue-like, phosphoacceptor receiver (REC) domain of hybrid sensor histidine kinase/response regulators similar to Pseudomonas savastanoi blue-light-activated histidine kinase. Typically, two-component regulatory systems (TCSs) consist of a sensor (histidine kinase) that responds to specific input(s) by modifying the output of a cognate response regulator (RR). TCSs allow organisms to sense and respond to changes in environmental conditions. Hybrid sensor histidine kinase (HK)/response regulators contain all the elements of a classical TCS in a single polypeptide chain. Pseudomonas savastanoi blue-light-activated histidine kinase is a photosensitive HK and RR that is involved in increased bacterial virulence upon exposure to light. RRs share the common phosphoacceptor REC domain and different effector/output domains such as DNA, RNA, ligand-binding, protein-binding, or enzymatic domains. REC domains function as phosphorylation-mediated switches within response regulators, but some also transfer phosphoryl groups in multistep phosphorelays.	3.86603e-21
NC_012808.1\|WP_015857409.1\|4673989_4675243_+\|ATP-binding-protein	gnl\|CDD\|237425	PRK13557, PRK13557, histidine kinase; Provisional.	2.25632e-88
NC_012808.1\|WP_003599057.1\|4681954_4683466_-\|NAD(P)/FAD-dependent-oxidoreductase	gnl\|CDD\|224983	COG2072, TrkA, Predicted flavoprotein involved in K+ transport [Inorganic ion transport and metabolism].	1.56775e-94

>NC_012808.1|WP_015857409.1|4673989_4675243_+|ATP-binding-protein
MLELLRRLWEVENLSPHGICLLWRPELIWTHVVSDSLIAFAYFSIPVGLAYFVSRRRDVVFGWMFWSFAVFITACGATHLMAIWTLWVPDYGLEAAVKLITGMASIGTAVALWVLIPKALTLPSPTQLRQANEALQARIAERDAALAALEAANAERARAEEALRQSQKMEAIGQLTGGVAHDFNNLLNVVLLNLDRVERGLPEASPLRTRLRDAVKGAERAATMTHKLLAFARRQPLSPVSTDVNAQIASFAEFLRGTIGPRIRLETDLAPDLPRVRIDPNQFESAILNLAVNARDAMPEGGTLTLATRPLPEGDGFAVEVSDTGAGMAPEVEARAFEPFFTTKPLGQGTGLGLSQVFGFAQQSGGSAAFVRDGRPGTTVRLSFPAQAPAVSRPAVRQAPVAEPGFAPLLPPVAVAG
>NC_012808.1|WP_043766524.1|4672291_4673692_-|acyl--CoA-ligase
MSAQRAITQVEASQRALQGALKGASQGTPDAASHETPADAPLRRISLGSLLSATARRHPDRIAVVDPADKPDWSDRPAITWTYAAAAEIVERLARGLRSWRLPPGSRIGLCLPGSAESALAILAVEAAGHVACLLPVSWDEDRLLAAAQNVALSAVLTQARLGSAAPAERLCAVAARYFGLRYLAAFGPDVPDGVINLDRFVLDGPAGEPAGPAPAAAGIVSFIGGDPEQPVYRSGESVVAAAAAHLVAMRVAPAERILSLIGPHDLRGLATGLAAALVAGATLETLPLFDGAAFATALRRPGPTHLVAPAFLEKNLAGRDLPTDLRSVALVHRAPVRFPSRSRAVDRSQGLRLETVIDTVAFDETAILSGRRGTTGDLSLVLGKPERLALPAALMSMRRGADDRLAFRGQACTVTPLQRGNRQAIPSGMWQETPYAPVLFAGFATAIEVVEPSASAGSPKIFAPA
>NC_012808.1|WP_003599081.1|4671691_4672033_-|hypothetical-protein
MGALQQVLVVDDGRRAVDRSLAADLAGLGYASVTASIEAADDVLAVIARPAAILLQLSSSTNPHLAALADRLRARMRAGGIPVIEMDDAGPRPGAPVDLKSRIGPYVLAEPEL
>NC_012808.1|WP_012255296.1|4671427_4671625_+|hypothetical-protein
MFHKFKIGQRVRRAQSSPTDERLGFGTISEVVRLMPDDPTGEPSYRIRSGSAERAVRESEIIAAA
>NC_012808.1|WP_003599084.1|4670880_4671249_+|hypothetical-protein
MSFTKQNSFDDRRQDSASSREAMLARFRARPSNDDPAVQARQAERRAIAVARDERVKERETQRRLDAERLAAIAAAEREAEVARKAAEIEAAAERAREAQAKQKEERDARYAARKAKIKLRR
>NC_012808.1|WP_003599086.1|4670568_4670778_+|cold-shock-protein
MSIGTVKWFNEQKGFGFIQPEDGSKDVFVHISAVERAGLRGLTEGQKVSYEMETDRRSGKQSAGQLQVA
>NC_012808.1|WP_003599088.1|4666601_4670192_+|transcription-repair-coupling-factor
MAKPQPKPPAPKPQTARFALPKSAPLTKALDAIKRGDSPTLASVPDGFDALVAADLARALSGSFEGPAVLVHVARDSGRSNAFQNALKFVAPEIEAMSVPAWDCQPYDRVSPNGAIAAQRMTALSRLTRSRSSEEKPRILCTTVNALVQRVPPRSRVAVETFSAAIGNVVPMDKVVAWVEANGFLRTGTVRDTGEYAVRGGILDLSPPGLPNPIRLDFFGDTLESIRAFDPETQRTVGSLRSLDLVPMSEVQLTTETIRRFRQGYLSSFGAATRDDRLYETVSEGRRYAGLEHWMPLFYDGLDTLFDYLGDVPMLFDPQVEEAATERLALIQDYFQAREAALKNPQSGVAPYKPLPPRALYLTPNEWKSKVESGTVVRLTPFATPDSDERAVIDCGARAGRSFAPERADDAASVFDAAVAHIRDLQASGHHVILGSWSEGSRDRLCGVLTDHGLKKPTVINTFAAVNALKRGTDVAVAVWGLESGFTLDRLAVVAEGDILGDRLVRQKRKSKRPQDIILEVQALQPGDLVVHADHGIGRFVTLKTVTAAGAPHDCLELQYAGGLLLLPVENIELLTRYGSEDSEVALDRLGGGAWQARKAKMKRRILEMAGDLIKIAAARFVKSAPSLKAPEGLYEEFAARFAFQETEDQANAIDAVLDDLNAGRPMDRLVCGDVGFGKTEVALRAAFAAAISGKQVAVVVPTTLLARQHFRTFAERFKGLPINVAQLSRFVSAGEQRQNRAGLADGTVDIVVGTHALLAKNVAFKDLGLIIVDEEQHFGVAHKERLKALQADVHVLTLSATPIPRTLQLAMTGVRELSIIATPPMDRLAVRTFVTPFDPLLVREALLRERYRGGQSFYVAPRIEDLAEVKRFLDTEMPETTVAVAHGQMAAGQLEDVMTAFYEGKYDVLLSTTIVESGLDIPTANTLIVHRADMFGLAALYQLRGRVGRSKARAYALFTTPANRQLTTQAEQRLKVLQSLDTLGAGFQLASHDLDIRGAGNLLGDAQSGHIKEVGYELYQQMLEDAVTALKAGIEEPVEEAWSPTIALGAPVTIPEDYVEDLTVRLGLYRRLSTLENDAEMESFGAELIDRFGPLPPEVEQLLKIVTIKILCRDANVEKVEAGPKGVVVHFRNRSFANPQGLAAMVVEQGSFAKVRPDMSVVFIRELDGIPRRLKETTQILRGLVTIAKRAKKAA
>NC_012808.1|WP_003599091.1|4666091_4666388_+|succinate-dehydrogenase-assembly-factor-2
MSGTTRTSADLDPRRRRTLFRAWHRGIREMDLIMGRFADAEIGALSEEELTQFEALIEVPDRDLFRWLTGEDATPENYDTAVYRRLKAFHRHDAPIHS
>NC_012808.1|WP_015857406.1|4663710_4665900_-|ATP-dependent-DNA-helicase-RecG
MTSDTSQTLGHPADAAPPRSGGDVAPGLRPSLLDPLFAPARGLPGVGPKIAPLIEKLLGSEERPARVADLLFHLPQSGVARPLCGSIRDAPTGEPVTLGVTVVAHRPPMLGKRAFRVLVEDGTGDISLVFFGMPRGRIEKMLPLGSHRYVSGRIDLWDGTRQMVHPSRILDQEGLASLPAVEPIYGATEGLTSRVISRIVHGALDRLPVLPEWQDASYLARNRFPPFAEALRIEHRPEEAPPPPVEGQALPASPARKRLAYDELLASQLALALVRARQRRKPGRVNAGDGHLKERVEAAMPFALTGAQARAVEEIRADMAAERRMLRLLQGDVGSGKTAVALLAMASAVEAGRQAALMAPTEILARQHYERLVPLAGAMRLRLLTGRDRAAERRATLADLAAGEIDIVVGTHALFQESVAFRDLGLAVVDEQHRFGVHQRLALGAKGEAVDILVMTATPIPRTLALTFFGDMDVSVLDEKPAGRQPIKTITVPVERIDEVVGGLHRALAAGDRVYWICPLVAESEYVDLAAAAERFEDLQKHFGDAVGLIHGKMPGPEKDAAMEAFAAGRTRVLVSTTVVEVGVDVPEATIMVIEHAERFGLAQLHQLRGRVGRGSKASSCLLLYRGPLGQVAKARLEMMRSSEDGFRIAEEDLRLRGEGEVLGTRQSGAAAFRLARLETDGDLLEAARDDARLIVERDPRLQSERGRALRVLLYLFEREAAIRLIGAG
>NC_012808.1|WP_131473064.1|4663416_4663641_-|hypothetical-protein
MIARSETDDPERVVQEAEAAAPDIPGCGNAAREKSVFRFQSSLCAASLALGTSVGQGRKSGITLYLPQLPLNWR
>NC_012808.1|WP_012255300.1|4675443_4675806_+|response-regulator
MADKRTVLVVEDEEMLLSAVTMEFEDAGFAVLSAGTAEEAYGLLQGAGRVDLLFTDIRLPGQLDGWDLAERARVLHPALPVIYVTGYSAEQPRQVSESVLVMKPYRMTAIMSAAQQLGVE
>NC_012808.1|WP_003599075.1|4675819_4676116_-|type-II-toxin-antitoxin-system-RelE/ParE-family-toxin
MGEVWSVRVRYTLTAARQIEAALDFLASESPQAAFRLQERILSVVALLQAHPQAGRLTSKRGIRRFPLSSFPYLIDYRATDRDIVVRRFRHTARRPLS
>NC_012808.1|WP_003599073.1|4676094_4676322_-|hypothetical-protein
MTDLLERAVATARGLSPEMQDEIARLVLAYAGEEQSVIPLTPEEEADLAESDVEEARGDFATEEQMRAIWAKYGR
>NC_012808.1|WP_003599070.1|4676365_4678003_-|acyl-CoA-synthetase
MARTTIYDRDLDPNPANFQPLTPLTYLDRAARTFPDRVAVIHGPLRRSYADLYARCRRLAAALAARGIGRGDTVAVLLANTPAMIECHYGVPMTGAVLNTLNTRLDAGALAFCLDHGEAKVFIVDREFARIGREALDKAGVSPLVIDYDDPEFTGDSAPVGETDYEDFLAAGDPDFGWAMPGDEWDAISLNYTSGTTGDPKGVVYHHRGAALLSLGNVITAGLPQHAVYLWTLPMFHCNGWCFPWTLSIVAGTHVCLRQVRAPAMYAALAEHGVTHLSGAPIVMSTLLNAPEAQKRPLPRRVHFLTAAAPPPEAVLAAMGEAGFDVTHLYGLTETYGPAVVNAWHEDWDALSRDEQARKKARQGVRYPVLEGLDVRDPETMESLPADGTSLGEVMFRGNVVMRGYLKNPASTEAAFKGGWFRSGDLGVKHPDGYIQLKDRSKDIIISGGENISSIEVEDALFKHPAVAAAAVVAKPDAKWGETPCAFIELKEGREATSEELVAWCRERLAPYKLPRHVVFGELPKTSTGKVQKFVLREKAREGDA
>NC_012808.1|WP_003599068.1|4678141_4678336_-|hypothetical-protein
MANNSANPYTLEIEACERPAGHFTWAIRRNGKLFQRADRVQTTEEAAERSGLAALEKLLSGRER
>NC_012808.1|WP_003599066.1|4678585_4680382_+|glycosyltransferase-family-39-protein
MTRLGVAPAALSQAEGGWPLDGALRLSDRVLSFGAASHLRACLLLLLIGLASFLPGLASLQPMDRDEPRFAQASKQMLETGDLVDIRFQAEARHKKPVGIYWAQAAAVAAGEALGVPQARTQIGLYRIPSLLGALAAILLTYWAGLALLDRRRALLAAALFSACIMLSAEARLAKTDALLTACSVAAFGALARAWLGRARLERRRGPASLGTALVFWLGIALGILVKGPMVPLFAGLAAFVLCLREGSARWLLDLRPRLGLLITLAVVAPWFLAIAWKSGGAFFGEAVGRDMLGKVGTGAEKHWGPPGAYALAFFATFWPGAAFAALSLPFAWARRGEEAVALLLAWIVPMWLIFEAVPTKLPHYVLPLMPAVAILTVLALSRGALDPRRPGARWVAGLVVLIPVGLTLGVSLAAWRLDHVLPLAALPLLFAACVLAGLAWAAFARGAREGAGRGTGPEAGEGALVLAVAASVVLSGAVFGLTQPVLQSLKVSPRLAAIRDALPCEAPRVASLGLREPSLVFTVGTDLAMLNSGAEAIAFLREGGCRVVLVEDRFAAEFATAQGGQPLSPVGRVTGFNINGGKPVGVSAYAALPGSTP
>NC_012808.1|WP_003599065.1|4680378_4681137_+|glycosyltransferase-family-2-protein
MSMTTQSEPPRLSVVVPVKNEAGNIEALVAEIGHACQTLAPFEVIYVDDGSTDATLATLRGLQAKHPWLRVVRHDRGGGQSGAVRSGVLRARAPVIATLDGDGQNDPSFIPVLYAALEQAGPTVGLAQGQRIGRKGAWKQFQSRIANGVRGKILKDATRDTGCGLKVFRREVYLTLPYFDALHRFMPALVTREGFGVVHRDVVDRPRFTGHSNYGMFDRLWVGILDLAGVWWLIRRRRPAPRAEEIPHSESR
>NC_012808.1|WP_003599063.1|4681141_4681471_+|lipid-A-disaccharide-synthase-N-terminal-domain-containing-protein
MLIQLAEDLPAYFYDVFVTRFDFWLVFGIGAQLVFGSRFILQWIASERAGKSVMPLSFWFLSIIGGLMTLVYGFVRREPVIIIGQGLSTFIYLRNLALIFRERRRARRA
>NC_012808.1|WP_003599059.1|4681486_4681951_+|DUF2721-domain-containing-protein
MFQTATGDPESIAHIIQVALAPAFLLSALATLLNVFSTRLGRVADKVDALSASLPGADEAARATLARRLAYLRRRSLLLDLAVVLASLGGVMTGAAVLTLFVGALRDASAASVLFACFGLALGCTILAILAFLAEILLAGRGIRLEVERKQDRP
>NC_012808.1|WP_003599057.1|4681954_4683466_-|NAD(P)/FAD-dependent-oxidoreductase
MSEAPLDLVIVGAGFSGLAMAIRARQAGFDRLLVLEKAAGVGGTWRENTYPGAACDVPSQLYSLSFAPKSDWSRLFAPQPEIEAYLEGLVAAHGLAPFLRLETCVTRAVFDAEAGLWRVETDRGVVSARVLVGAMGALHHPALPRLPGLERFSGKAFHSATWDHSCDLRAKRVGVIGTGASAVQFVPEIVGRVAHLTQFQRSAPWILPRGDRPTGRGFQWLMRIAPLRRLHRASLFWRREVAALAGFTRVSRVTALAEAWSRRHLAASIADPALRRQLTPDYRLGCKRVLLSDDYYPALARPNASLVTAPIREVLPHGIVTADGAEHPLDMLIFATGFAPGGSVVRTEVIGRDGLSLLQAWKQGADAFRGVSVAGFPNFFLLLGPNTGLGHNSVLLMVEAQVAHVLGALKRLRDQPGGVLEVRPEAQARFRAEVDARMQDSIWTQGGCGSWYLDRAGRNRTLWPGTVGDYVRGTERMRVEDYRLTDPPGLCPGPTKGLVLSKP

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NC_012808_3	3.2\|2521942\|25\|NC_012808\|CRISPRCasFinder	2521942-2521966	25	CP007644	Rhizobium etli bv. phaseoli str. IE4803 plasmid pRetIE4803c, complete sequence	217593-217617	4	0.84
NC_012808_3	3.1\|2521888\|31\|NC_012808\|CRISPRCasFinder	2521888-2521918	31	NZ_CP010408	Streptomyces vietnamensis strain GIMV4.0001 plasmid pSVL1, complete sequence	46469-46499	5	0.839
NC_012808_3	3.1\|2521888\|31\|NC_012808\|CRISPRCasFinder	2521888-2521918	31	NZ_LR134451	Tsukamurella tyrosinosolvens strain NCTC13231 plasmid 9, complete sequence	745-775	5	0.839
NC_012808_3	3.1\|2521888\|31\|NC_012808\|CRISPRCasFinder	2521888-2521918	31	NZ_CP017422	Arthrobacter sp. ZXY-2 plasmid pZXY21, complete sequence	256369-256399	6	0.806
NC_012808_3	3.1\|2521888\|31\|NC_012808\|CRISPRCasFinder	2521888-2521918	31	NZ_CP039697	Novosphingobium sp. ABRDHK2 plasmid pABRDHK22, complete sequence	681520-681550	6	0.806
NC_012808_3	3.1\|2521888\|31\|NC_012808\|CRISPRCasFinder	2521888-2521918	31	NZ_CP023549	Rhodobacter sp. CZR27 plasmid unnamed1, complete sequence	62521-62551	6	0.806
NC_012808_3	3.1\|2521888\|31\|NC_012808\|CRISPRCasFinder	2521888-2521918	31	NZ_CP048420	Sphingomonas insulae strain KCTC 12872 plasmid unnamed2, complete sequence	70285-70315	6	0.806
NC_012808_3	3.1\|2521888\|31\|NC_012808\|CRISPRCasFinder	2521888-2521918	31	NC_006569	Ruegeria pomeroyi DSS-3 megaplasmid, complete sequence	30928-30958	6	0.806
NC_012808_3	3.1\|2521888\|31\|NC_012808\|CRISPRCasFinder	2521888-2521918	31	NZ_CP018784	Curtobacterium pusillum strain AA3 plasmid pCPAA3, complete sequence	498426-498456	8	0.742
NC_012808_3	3.1\|2521888\|31\|NC_012808\|CRISPRCasFinder	2521888-2521918	31	CP007644	Rhizobium etli bv. phaseoli str. IE4803 plasmid pRetIE4803c, complete sequence	21554-21584	8	0.742
NC_012808_3	3.1\|2521888\|31\|NC_012808\|CRISPRCasFinder	2521888-2521918	31	NZ_CP050095	Rhizobium leguminosarum bv. trifolii strain 22B plasmid pRL22b1, complete sequence	109422-109452	8	0.742
NC_012808_3	3.1\|2521888\|31\|NC_012808\|CRISPRCasFinder	2521888-2521918	31	NZ_CP050083	Rhizobium leguminosarum bv. trifolii strain 31B plasmid pRL31b3, complete sequence	165370-165400	8	0.742
NC_012808_3	3.1\|2521888\|31\|NC_012808\|CRISPRCasFinder	2521888-2521918	31	NZ_CP050100	Rhizobium leguminosarum bv. trifolii strain 9B plasmid pRL9b3, complete sequence	101792-101822	8	0.742
NC_012808_3	3.1\|2521888\|31\|NC_012808\|CRISPRCasFinder	2521888-2521918	31	NC_008381	Rhizobium leguminosarum bv. viciae 3841 plasmid pRL10, complete sequence	306491-306521	8	0.742
NC_012808_3	3.1\|2521888\|31\|NC_012808\|CRISPRCasFinder	2521888-2521918	31	NZ_CP025017	Rhizobium leguminosarum strain Norway plasmid pRLN5, complete sequence	97123-97153	8	0.742
NC_012808_3	3.1\|2521888\|31\|NC_012808\|CRISPRCasFinder	2521888-2521918	31	NZ_CP049733	Rhizobium leguminosarum strain A1 plasmid pRL10, complete sequence	156629-156659	8	0.742
NC_012808_3	3.1\|2521888\|31\|NC_012808\|CRISPRCasFinder	2521888-2521918	31	NZ_CP053443	Rhizobium leguminosarum bv. trifolii strain CC275e plasmid pRltCC275eC, complete sequence	77895-77925	8	0.742
NC_012808_3	3.1\|2521888\|31\|NC_012808\|CRISPRCasFinder	2521888-2521918	31	NZ_CP048284	Rhizobium leguminosarum bv. viciae 248 plasmid pRle248b, complete sequence	98593-98623	8	0.742
NC_012808_3	3.1\|2521888\|31\|NC_012808\|CRISPRCasFinder	2521888-2521918	31	NZ_CP054026	Rhizobium sp. JKLM12A2 plasmid pPR12A205, complete sequence	129091-129121	8	0.742
NC_012808_3	3.1\|2521888\|31\|NC_012808\|CRISPRCasFinder	2521888-2521918	31	NZ_CP054036	Rhizobium sp. JKLM13E plasmid pPR13E05, complete sequence	255135-255165	8	0.742
NC_012808_3	3.1\|2521888\|31\|NC_012808\|CRISPRCasFinder	2521888-2521918	31	NZ_CP053207	Rhizobium leguminosarum bv. trifolii TA1 plasmid pRltTA1C, complete sequence	187281-187311	8	0.742
NC_012808_3	3.1\|2521888\|31\|NC_012808\|CRISPRCasFinder	2521888-2521918	31	NZ_CP050106	Rhizobium leguminosarum bv. trifolii strain 4B plasmid pRL4b5, complete sequence	359536-359566	8	0.742
NC_012808_3	3.1\|2521888\|31\|NC_012808\|CRISPRCasFinder	2521888-2521918	31	NC_012854	Rhizobium leguminosarum bv. trifolii WSM1325 plasmid pR132505, complete sequence	227486-227516	8	0.742
NC_012808_3	3.1\|2521888\|31\|NC_012808\|CRISPRCasFinder	2521888-2521918	31	NZ_CP018232	Rhizobium leguminosarum strain Vaf-108 plasmid unnamed4, complete sequence	218220-218250	8	0.742
NC_012808_3	3.1\|2521888\|31\|NC_012808\|CRISPRCasFinder	2521888-2521918	31	NZ_CP025506	Rhizobium leguminosarum bv. viciae strain UPM791 plasmid pRlvE, complete sequence	350341-350371	8	0.742
NC_012808_3	3.1\|2521888\|31\|NC_012808\|CRISPRCasFinder	2521888-2521918	31	NZ_CP050111	Rhizobium leguminosarum bv. trifolii strain 3B plasmid pRL3b1, complete sequence	359720-359750	8	0.742
NC_012808_3	3.1\|2521888\|31\|NC_012808\|CRISPRCasFinder	2521888-2521918	31	NZ_CP030763	Rhizobium leguminosarum strain ATCC 14479 plasmid unnamed3, complete sequence	22889-22919	8	0.742
NC_012808_3	3.1\|2521888\|31\|NC_012808\|CRISPRCasFinder	2521888-2521918	31	NZ_CP022668	Rhizobium leguminosarum bv. viciae strain BIHB 1217 plasmid pPR3, complete sequence	238448-238478	8	0.742
NC_012808_3	3.1\|2521888\|31\|NC_012808\|CRISPRCasFinder	2521888-2521918	31	NZ_CP022568	Rhizobium leguminosarum bv. viciae strain BIHB 1148 plasmid pSK04, complete sequence	289251-289281	8	0.742
NC_012808_3	3.1\|2521888\|31\|NC_012808\|CRISPRCasFinder	2521888-2521918	31	NZ_CP050088	Rhizobium leguminosarum bv. trifolii strain 23B plasmid pRL23b6, complete sequence	496042-496072	8	0.742
NC_012808_3	3.1\|2521888\|31\|NC_012808\|CRISPRCasFinder	2521888-2521918	31	NZ_CP028969	Aminobacter sp. MSH1 plasmid pUSP1, complete sequence	272474-272504	9	0.71
NC_012808_3	3.1\|2521888\|31\|NC_012808\|CRISPRCasFinder	2521888-2521918	31	NZ_CP026266	Aminobacter sp. MSH1 plasmid pAM01, complete sequence	269751-269781	9	0.71
NC_012808_3	3.1\|2521888\|31\|NC_012808\|CRISPRCasFinder	2521888-2521918	31	CP047389	Agrobacterium sp. CGMCC 11546 plasmid pA	170400-170430	9	0.71
NC_012808_3	3.1\|2521888\|31\|NC_012808\|CRISPRCasFinder	2521888-2521918	31	NZ_CP015007	Aminobacter aminovorans strain KCTC 2477 plasmid pAA02, complete sequence	276449-276479	9	0.71

1. spacer 3.2|2521942|25|NC_012808|CRISPRCasFinder matches to CP007644 (Rhizobium etli bv. phaseoli str. IE4803 plasmid pRetIE4803c, complete sequence) position: , mismatch: 4, identity: 0.84

tagcggccaagccgatttcgaggcc	CRISPR spacer
aagcgcccaagccgagttcgaggct	Protospacer
 **** ********* ********.

2. spacer 3.1|2521888|31|NC_012808|CRISPRCasFinder matches to NZ_CP010408 (Streptomyces vietnamensis strain GIMV4.0001 plasmid pSVL1, complete sequence) position: , mismatch: 5, identity: 0.839

cacgggccgcgacacgatcaccatcggcgac	CRISPR spacer
catccgccgcgacacgatcgccttcggcgac	Protospacer
**.  **************.** ********

3. spacer 3.1|2521888|31|NC_012808|CRISPRCasFinder matches to NZ_LR134451 (Tsukamurella tyrosinosolvens strain NCTC13231 plasmid 9, complete sequence) position: , mismatch: 5, identity: 0.839

-cacgggccgcgacacgatcaccatcggcgac	CRISPR spacer
gcac-caccgcgacccgatccccatcggcgac	Protospacer
 ***  .******* ***** ***********

4. spacer 3.1|2521888|31|NC_012808|CRISPRCasFinder matches to NZ_CP017422 (Arthrobacter sp. ZXY-2 plasmid pZXY21, complete sequence) position: , mismatch: 6, identity: 0.806

cacgggccgcgacacgatcaccatcggcgac	CRISPR spacer
ctacgacggcgacacgatcaccatcggcaac	Protospacer
*   *.* ********************.**

5. spacer 3.1|2521888|31|NC_012808|CRISPRCasFinder matches to NZ_CP039697 (Novosphingobium sp. ABRDHK2 plasmid pABRDHK22, complete sequence) position: , mismatch: 6, identity: 0.806

-cacgggccgcgacacgatcaccatcggcgac	CRISPR spacer
cgacaagac-cggcacgatcaccatcggcgac	Protospacer
  **..* * **.*******************

6. spacer 3.1|2521888|31|NC_012808|CRISPRCasFinder matches to NZ_CP023549 (Rhodobacter sp. CZR27 plasmid unnamed1, complete sequence) position: , mismatch: 6, identity: 0.806

cacgggccgcgacacgatcaccatcggcgac	CRISPR spacer
cacggtccgcgacacgatcaccgacttcgtc	Protospacer
***** ****************. *  ** *

7. spacer 3.1|2521888|31|NC_012808|CRISPRCasFinder matches to NZ_CP048420 (Sphingomonas insulae strain KCTC 12872 plasmid unnamed2, complete sequence) position: , mismatch: 6, identity: 0.806

-cacgggccgcgacacgatcaccatcggcgac	CRISPR spacer
cgacaagac-cggcacgatcaccatcggcgac	Protospacer
  **..* * **.*******************

8. spacer 3.1|2521888|31|NC_012808|CRISPRCasFinder matches to NC_006569 (Ruegeria pomeroyi DSS-3 megaplasmid, complete sequence) position: , mismatch: 6, identity: 0.806

cacgggccgcgacacgatcaccatcggcgac	CRISPR spacer
caagctctgcggcatgatcaccatcggcgac	Protospacer
** *  *.***.**.****************

9. spacer 3.1|2521888|31|NC_012808|CRISPRCasFinder matches to NZ_CP018784 (Curtobacterium pusillum strain AA3 plasmid pCPAA3, complete sequence) position: , mismatch: 8, identity: 0.742

cacgggccgcgacacgatcaccatcggcgac	CRISPR spacer
cggcaaacgcgacaccgtcaccatcggcgac	Protospacer
*.  .. ******** .**************

10. spacer 3.1|2521888|31|NC_012808|CRISPRCasFinder matches to CP007644 (Rhizobium etli bv. phaseoli str. IE4803 plasmid pRetIE4803c, complete sequence) position: , mismatch: 8, identity: 0.742

cacgggccgcgacacgatcaccatcggcgac	CRISPR spacer
ctatcccggcgtcacgatcaccatccgcgac	Protospacer
*     * *** ************* *****

11. spacer 3.1|2521888|31|NC_012808|CRISPRCasFinder matches to NZ_CP050095 (Rhizobium leguminosarum bv. trifolii strain 22B plasmid pRL22b1, complete sequence) position: , mismatch: 8, identity: 0.742

cacgggccgcgacacgatcaccatcggcgac	CRISPR spacer
cccccttggcgacacgatcgccgtcggcgac	Protospacer
* *   . ***********.**.********

12. spacer 3.1|2521888|31|NC_012808|CRISPRCasFinder matches to NZ_CP050083 (Rhizobium leguminosarum bv. trifolii strain 31B plasmid pRL31b3, complete sequence) position: , mismatch: 8, identity: 0.742

cacgggccgcgacacgatcaccatcggcgac	CRISPR spacer
cccccttggcgacacgatcgccttcggcgac	Protospacer
* *   . ***********.** ********

13. spacer 3.1|2521888|31|NC_012808|CRISPRCasFinder matches to NZ_CP050100 (Rhizobium leguminosarum bv. trifolii strain 9B plasmid pRL9b3, complete sequence) position: , mismatch: 8, identity: 0.742

cacgggccgcgacacgatcaccatcggcgac	CRISPR spacer
cgcccctggcgacacgatcgccttcggcgac	Protospacer
*.*   . ***********.** ********

14. spacer 3.1|2521888|31|NC_012808|CRISPRCasFinder matches to NC_008381 (Rhizobium leguminosarum bv. viciae 3841 plasmid pRL10, complete sequence) position: , mismatch: 8, identity: 0.742

cacgggccgcgacacgatcaccatcggcgac	CRISPR spacer
cccccttggcgacacgatcgccgtcggcgac	Protospacer
* *   . ***********.**.********

15. spacer 3.1|2521888|31|NC_012808|CRISPRCasFinder matches to NZ_CP025017 (Rhizobium leguminosarum strain Norway plasmid pRLN5, complete sequence) position: , mismatch: 8, identity: 0.742

cacgggccgcgacacgatcaccatcggcgac	CRISPR spacer
cccccttggcgacacgatcgccctcggcgac	Protospacer
* *   . ***********.** ********

16. spacer 3.1|2521888|31|NC_012808|CRISPRCasFinder matches to NZ_CP049733 (Rhizobium leguminosarum strain A1 plasmid pRL10, complete sequence) position: , mismatch: 8, identity: 0.742

cacgggccgcgacacgatcaccatcggcgac	CRISPR spacer
cccccttggcgacacgatcgccttcggcgac	Protospacer
* *   . ***********.** ********

17. spacer 3.1|2521888|31|NC_012808|CRISPRCasFinder matches to NZ_CP053443 (Rhizobium leguminosarum bv. trifolii strain CC275e plasmid pRltCC275eC, complete sequence) position: , mismatch: 8, identity: 0.742

cacgggccgcgacacgatcaccatcggcgac	CRISPR spacer
cgcccctggcgacacgatcgccttcggcgac	Protospacer
*.*   . ***********.** ********

18. spacer 3.1|2521888|31|NC_012808|CRISPRCasFinder matches to NZ_CP048284 (Rhizobium leguminosarum bv. viciae 248 plasmid pRle248b, complete sequence) position: , mismatch: 8, identity: 0.742

cacgggccgcgacacgatcaccatcggcgac	CRISPR spacer
cccccttggcgacacgatcgccgtcggcgac	Protospacer
* *   . ***********.**.********

19. spacer 3.1|2521888|31|NC_012808|CRISPRCasFinder matches to NZ_CP054026 (Rhizobium sp. JKLM12A2 plasmid pPR12A205, complete sequence) position: , mismatch: 8, identity: 0.742

cacgggccgcgacacgatcaccatcggcgac	CRISPR spacer
cccccttggcgacacgatcgccgtcggcgac	Protospacer
* *   . ***********.**.********

20. spacer 3.1|2521888|31|NC_012808|CRISPRCasFinder matches to NZ_CP054036 (Rhizobium sp. JKLM13E plasmid pPR13E05, complete sequence) position: , mismatch: 8, identity: 0.742

cacgggccgcgacacgatcaccatcggcgac	CRISPR spacer
cccccttggcgacacgatcgccgtcggcgac	Protospacer
* *   . ***********.**.********

21. spacer 3.1|2521888|31|NC_012808|CRISPRCasFinder matches to NZ_CP053207 (Rhizobium leguminosarum bv. trifolii TA1 plasmid pRltTA1C, complete sequence) position: , mismatch: 8, identity: 0.742

cacgggccgcgacacgatcaccatcggcgac	CRISPR spacer
cccccttggcgacacgatcgccttcggcgac	Protospacer
* *   . ***********.** ********

22. spacer 3.1|2521888|31|NC_012808|CRISPRCasFinder matches to NZ_CP050106 (Rhizobium leguminosarum bv. trifolii strain 4B plasmid pRL4b5, complete sequence) position: , mismatch: 8, identity: 0.742

cacgggccgcgacacgatcaccatcggcgac	CRISPR spacer
cccccttggcgacacgatcgccttcggcgac	Protospacer
* *   . ***********.** ********

23. spacer 3.1|2521888|31|NC_012808|CRISPRCasFinder matches to NC_012854 (Rhizobium leguminosarum bv. trifolii WSM1325 plasmid pR132505, complete sequence) position: , mismatch: 8, identity: 0.742

cacgggccgcgacacgatcaccatcggcgac	CRISPR spacer
cgcccttggcgacacgatcgccgtcggcgac	Protospacer
*.*   . ***********.**.********

24. spacer 3.1|2521888|31|NC_012808|CRISPRCasFinder matches to NZ_CP018232 (Rhizobium leguminosarum strain Vaf-108 plasmid unnamed4, complete sequence) position: , mismatch: 8, identity: 0.742

cacgggccgcgacacgatcaccatcggcgac	CRISPR spacer
cccccttggcgacacgatcgccttcggcgac	Protospacer
* *   . ***********.** ********

25. spacer 3.1|2521888|31|NC_012808|CRISPRCasFinder matches to NZ_CP025506 (Rhizobium leguminosarum bv. viciae strain UPM791 plasmid pRlvE, complete sequence) position: , mismatch: 8, identity: 0.742

cacgggccgcgacacgatcaccatcggcgac	CRISPR spacer
cccccttggcgacacgatcgccttcggcgac	Protospacer
* *   . ***********.** ********

26. spacer 3.1|2521888|31|NC_012808|CRISPRCasFinder matches to NZ_CP050111 (Rhizobium leguminosarum bv. trifolii strain 3B plasmid pRL3b1, complete sequence) position: , mismatch: 8, identity: 0.742

cacgggccgcgacacgatcaccatcggcgac	CRISPR spacer
cccccttggcgacacgatcgccttcggcgac	Protospacer
* *   . ***********.** ********

27. spacer 3.1|2521888|31|NC_012808|CRISPRCasFinder matches to NZ_CP030763 (Rhizobium leguminosarum strain ATCC 14479 plasmid unnamed3, complete sequence) position: , mismatch: 8, identity: 0.742

cacgggccgcgacacgatcaccatcggcgac	CRISPR spacer
cccccttggcgacacgatcgccttcggcgac	Protospacer
* *   . ***********.** ********

28. spacer 3.1|2521888|31|NC_012808|CRISPRCasFinder matches to NZ_CP022668 (Rhizobium leguminosarum bv. viciae strain BIHB 1217 plasmid pPR3, complete sequence) position: , mismatch: 8, identity: 0.742

cacgggccgcgacacgatcaccatcggcgac	CRISPR spacer
cccccttggcgacacgatcgccttcggcgac	Protospacer
* *   . ***********.** ********

29. spacer 3.1|2521888|31|NC_012808|CRISPRCasFinder matches to NZ_CP022568 (Rhizobium leguminosarum bv. viciae strain BIHB 1148 plasmid pSK04, complete sequence) position: , mismatch: 8, identity: 0.742

cacgggccgcgacacgatcaccatcggcgac	CRISPR spacer
cccccttggcgacacgatcgccttcggcgac	Protospacer
* *   . ***********.** ********

30. spacer 3.1|2521888|31|NC_012808|CRISPRCasFinder matches to NZ_CP050088 (Rhizobium leguminosarum bv. trifolii strain 23B plasmid pRL23b6, complete sequence) position: , mismatch: 8, identity: 0.742

cacgggccgcgacacgatcaccatcggcgac	CRISPR spacer
cccccttggcgacacgatcgccttcggcgac	Protospacer
* *   . ***********.** ********

31. spacer 3.1|2521888|31|NC_012808|CRISPRCasFinder matches to NZ_CP028969 (Aminobacter sp. MSH1 plasmid pUSP1, complete sequence) position: , mismatch: 9, identity: 0.71

cacgggccgcgacacgatcaccatcggcgac	CRISPR spacer
ggcaagccgcgatccgatcaccatcggctca	Protospacer
 .*..*******. **************

32. spacer 3.1|2521888|31|NC_012808|CRISPRCasFinder matches to NZ_CP026266 (Aminobacter sp. MSH1 plasmid pAM01, complete sequence) position: , mismatch: 9, identity: 0.71

cacgggccgcgacacgatcaccatcggcgac	CRISPR spacer
ggcaagccgcgatccgatcaccatcggctca	Protospacer
 .*..*******. **************

33. spacer 3.1|2521888|31|NC_012808|CRISPRCasFinder matches to CP047389 (Agrobacterium sp. CGMCC 11546 plasmid pA) position: , mismatch: 9, identity: 0.71

cacgggccgcgacacgatcaccatcggcgac	CRISPR spacer
agtcgatcgcaacgcgatcaccatcggcgag	Protospacer
 .. *..***.**.****************

34. spacer 3.1|2521888|31|NC_012808|CRISPRCasFinder matches to NZ_CP015007 (Aminobacter aminovorans strain KCTC 2477 plasmid pAA02, complete sequence) position: , mismatch: 9, identity: 0.71

cacgggccgcgacacgatcaccatcggcgac	CRISPR spacer
gttgagccgcgccacgatcgccatcggcagt	Protospacer
  .*.****** *******.********...

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

867357 : 937864

Mycobacterium_phage(27.27%)

tRNA,transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_003598172.1\|867357_868683_-\|tRNA	proline--tRNA ligase	A0A2K9L6B6	Tupanvirus	7.6e-06	24.0
WP_012752224.1\|869158_869500_-	DUF1467 family protein	NA	NA	NA	NA
WP_003598176.1\|869565_869970_-	methylmalonyl-CoA epimerase	NA	NA	NA	NA
WP_003598177.1\|870120_871794_-	ribonuclease J	NA	NA	NA	NA
WP_003598178.1\|871813_872653_-	biotin--[acetyl-CoA-carboxylase] ligase	NA	NA	NA	NA
WP_003598179.1\|872672_874112_-	NADH-quinone oxidoreductase subunit NuoN	NA	NA	NA	NA
WP_003598180.1\|874108_875692_-	NADH-quinone oxidoreductase subunit M	NA	NA	NA	NA
WP_003598181.1\|875691_877803_-	NADH-quinone oxidoreductase subunit L	NA	NA	NA	NA
WP_003598182.1\|877861_878167_-	NADH-quinone oxidoreductase subunit NuoK	NA	NA	NA	NA
WP_003598184.1\|878172_878793_-	NADH-quinone oxidoreductase subunit J	NA	NA	NA	NA
WP_003598186.1\|879002_879491_-	NADH-quinone oxidoreductase subunit NuoI	NA	NA	NA	NA
WP_003598188.1\|879575_880598_-	NADH-quinone oxidoreductase subunit NuoH	NA	NA	NA	NA
WP_003598190.1\|880610_882677_-	NADH-quinone oxidoreductase subunit G	NA	NA	NA	NA
WP_003598192.1\|882711_884013_-	NADH-quinone oxidoreductase subunit NuoF	NA	NA	NA	NA
WP_003598194.1\|884023_885262_-	NADH-quinone oxidoreductase subunit NuoE	NA	NA	NA	NA
WP_003598196.1\|885280_886471_-	NADH-quinone oxidoreductase subunit D	NA	NA	NA	NA
WP_003598198.1\|886482_887142_-	NADH-quinone oxidoreductase subunit C	NA	NA	NA	NA
WP_003598199.1\|887153_887741_-	NADH-quinone oxidoreductase subunit B	NA	NA	NA	NA
WP_003598200.1\|887793_888159_-	NADH-quinone oxidoreductase subunit A	NA	NA	NA	NA
WP_003598202.1\|888990_889479_+	CAP domain-containing protein	NA	NA	NA	NA
WP_012752226.1\|889524_889971_-	pseudoazurin	NA	NA	NA	NA
WP_003598206.1\|890266_893740_+	carbamoyl-phosphate synthase large subunit	NA	NA	NA	NA
WP_173390180.1\|893876_894353_+	transcription elongation factor GreA	NA	NA	NA	NA
WP_003598208.1\|894357_894858_+	hypothetical protein	NA	NA	NA	NA
WP_003598210.1\|894868_895993_+	mitochondrial fission ELM1 family protein	NA	NA	NA	NA
WP_003598212.1\|896143_897118_+	thioredoxin-disulfide reductase	A0A2I2L5E1	Orpheovirus	8.8e-68	45.2
WP_003598214.1\|897458_898349_+	LysR family transcriptional regulator	NA	NA	NA	NA
WP_003598216.1\|898465_898921_+	type II 3-dehydroquinate dehydratase	NA	NA	NA	NA
WP_012752228.1\|898939_899410_+	acetyl-CoA carboxylase biotin carboxyl carrier protein	NA	NA	NA	NA
WP_003598219.1\|899420_900788_+	acetyl-CoA carboxylase biotin carboxylase subunit	NA	NA	NA	NA
WP_003598221.1\|900872_901547_+\|tRNA	leucyl/phenylalanyl-tRNA--protein transferase	NA	NA	NA	NA
WP_003598222.1\|901612_902233_-	TetR/AcrR family transcriptional regulator	NA	NA	NA	NA
WP_003598226.1\|902280_902760_+	DUF4188 domain-containing protein	NA	NA	NA	NA
WP_003598227.1\|902859_903519_-	DUF2155 domain-containing protein	NA	NA	NA	NA
WP_012752230.1\|903698_904115_-	NADH:ubiquinone oxidoreductase subunit NDUFA12	NA	NA	NA	NA
WP_012752231.1\|904634_908366_+	vitamin B12-dependent ribonucleotide reductase	A0A1X9SGV9	Bradyrhizobium_phage	0.0e+00	56.2
WP_080577072.1\|908637_909762_+	cyclic nucleotide-binding domain-containing protein	A0A218MLZ2	uncultured_virus	2.5e-13	38.7
WP_009867550.1\|910161_911430_-\|transposase	IS256-like element ISMex3 family transposase	A0A2P1JQX9	Mycobacterium_phage	2.5e-91	45.7
WP_190273131.1\|913054_913225_-	hypothetical protein	NA	NA	NA	NA
WP_085985461.1\|913884_914995_+\|transposase	IS3-like element ISMex1 family transposase	S5WIU1	Leptospira_phage	3.4e-47	40.3
WP_012752237.1\|916759_917812_+	hypothetical protein	NA	NA	NA	NA
WP_003605493.1\|917847_918981_+	metallophosphoesterase	NA	NA	NA	NA
WP_003605492.1\|919383_919743_-	DUF1476 family protein	NA	NA	NA	NA
WP_003603602.1\|919984_920215_+	hypothetical protein	NA	NA	NA	NA
WP_009867550.1\|920501_921770_-\|transposase	IS256-like element ISMex3 family transposase	A0A2P1JQX9	Mycobacterium_phage	2.5e-91	45.7
WP_043765884.1\|921984_922482_-	ferritin-like domain-containing protein	NA	NA	NA	NA
WP_003603598.1\|922853_924338_-	DUF2252 domain-containing protein	NA	NA	NA	NA
WP_003603596.1\|924805_925645_+	formate/nitrite transporter family protein	NA	NA	NA	NA
WP_085985459.1\|927313_928425_-\|transposase	IS3-like element ISMex1 family transposase	S5WIU1	Leptospira_phage	6.8e-48	40.7
WP_003596089.1\|929076_930285_-\|transposase	IS256-like element ISMex14 family transposase	A0A220NQR7	Corynebacterium_phage	4.9e-92	48.5
WP_003603591.1\|930824_932843_-	glycosyltransferase	M1IME2	Acanthocystis_turfacea_Chlorella_virus	1.8e-35	36.1
WP_043765886.1\|932824_934060_-	HlyD family efflux transporter periplasmic adaptor subunit	NA	NA	NA	NA
WP_003605095.1\|935838_936204_+	hypothetical protein	NA	NA	NA	NA
WP_009867550.1\|936595_937864_+\|transposase	IS256-like element ISMex3 family transposase	A0A2P1JQX9	Mycobacterium_phage	2.5e-91	45.7

DBSCAN-SWA_2

1112451 : 1147232

Leptospira_phage(33.33%)

integrase,transposase

attL 1127861:1127920|attR 1155492:1156694

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_085985459.1\|1112451_1113563_-\|transposase	IS3-like element ISMex1 family transposase	S5WIU1	Leptospira_phage	6.8e-48	40.7
WP_012752308.1\|1114319_1115348_-	urea transporter	NA	NA	NA	NA
WP_012752309.1\|1115363_1116299_-	urease accessory protein UreD	NA	NA	NA	NA
WP_012252936.1\|1116303_1116951_-	urease accessory protein UreG	NA	NA	NA	NA
WP_012752310.1\|1116971_1117652_-	urease accessory protein UreF	NA	NA	NA	NA
WP_012752311.1\|1117693_1118347_-	urease accessory protein UreE	NA	NA	NA	NA
WP_012752312.1\|1118370_1118754_-	fluoride efflux transporter CrcB	NA	NA	NA	NA
WP_043766716.1\|1118763_1119147_-	CrcB family protein	NA	NA	NA	NA
WP_012752314.1\|1119208_1120927_-	urease subunit alpha	NA	NA	NA	NA
WP_082222786.1\|1120963_1121374_-	urease subunit beta	NA	NA	NA	NA
WP_012752316.1\|1121398_1121701_-	urease subunit gamma	NA	NA	NA	NA
WP_012752317.1\|1122340_1124455_+	TonB-dependent receptor	NA	NA	NA	NA
WP_012752318.1\|1124451_1125183_+	DUF4198 domain-containing protein	NA	NA	NA	NA
WP_012752319.1\|1126012_1126366_+	hypothetical protein	NA	NA	NA	NA
WP_012752320.1\|1126410_1127316_+	PHB depolymerase family esterase	NA	NA	NA	NA
WP_043766719.1\|1127370_1127865_+	transglutaminase	NA	NA	NA	NA
1127861:1127920	attL	NA	NA	NA	NA
WP_085985459.1\|1127924_1129035_+\|transposase	IS3-like element ISMex1 family transposase	S5WIU1	Leptospira_phage	6.8e-48	40.7
WP_158022426.1\|1129072_1129324_+	hypothetical protein	NA	NA	NA	NA
WP_085985463.1\|1129748_1130710_-\|transposase	IS630-like element ISMex21 family transposase	A0A1V0SCG6	Indivirus	7.2e-14	24.4
WP_158022354.1\|1131506_1135025_+	hypothetical protein	NA	NA	NA	NA
WP_158022355.1\|1135021_1135489_+	response regulator	NA	NA	NA	NA
WP_012752323.1\|1135481_1136708_+	response regulator	NA	NA	NA	NA
WP_012752324.1\|1136991_1137555_+	recombinase family protein	Q1MVP4	Enterobacteria_phage	3.6e-29	42.2
WP_043765794.1\|1137812_1139156_+\|transposase	IS1380-like element ISMex4 family transposase	NA	NA	NA	NA
WP_012752325.1\|1140024_1140447_+	hypothetical protein	NA	NA	NA	NA
WP_158022356.1\|1141933_1144348_-	hypothetical protein	NA	NA	NA	NA
WP_082222788.1\|1144625_1145642_-\|integrase	site-specific integrase	A0A0A1I5U0	Burkholderia_phage	7.8e-51	36.1
WP_009867550.1\|1145963_1147232_-\|transposase	IS256-like element ISMex3 family transposase	A0A2P1JQX9	Mycobacterium_phage	2.5e-91	45.7
1155492:1156694	attR	NA	NA	NA	NA

DBSCAN-SWA_3

1360528 : 1373067

Paracoccus_phage(37.5%)

head,protease,tail

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_012752449.1\|1360528_1361092_-	lysozyme	W6E9Q2	Rhizobium_phage	3.1e-25	41.4
WP_003607221.1\|1361211_1362294_-	DUF2793 domain-containing protein	A0A0K1LM04	Rhodobacter_phage	7.6e-36	39.6
WP_012752450.1\|1362318_1366227_-	glycoside hydrolase TIM-barrel-like domain-containing protein	A0A0B5A7K5	Paracoccus_phage	1.5e-171	33.2
WP_003606565.1\|1366279_1366744_-	C40 family peptidase	A0A1V0DYB6	Dinoroseobacter_phage	6.5e-29	46.1
WP_003606566.1\|1366751_1367645_-	DUF2163 domain-containing protein	A0A0B5A5B8	Paracoccus_phage	3.6e-60	42.4
WP_003606567.1\|1367654_1368296_-	DUF2460 domain-containing protein	A0A0B5A2K3	Paracoccus_phage	3.7e-46	50.0
WP_012752451.1\|1368307_1368934_-\|tail	phage tail tape measure protein	G9JXH3	Shigella_phage	5.6e-07	66.7
WP_012752452.1\|1368930_1369164_-\|tail	phage tail assembly chaperone	NA	NA	NA	NA
WP_043765964.1\|1369160_1369487_-	gene transfer agent family protein	NA	NA	NA	NA
WP_003607717.1\|1369489_1369900_-\|tail	phage major tail protein, TP901-1 family	NA	NA	NA	NA
WP_003607719.1\|1369928_1370348_-	DUF3168 domain-containing protein	NA	NA	NA	NA
WP_012752454.1\|1370344_1370686_-\|head,tail	head-tail adaptor protein	NA	NA	NA	NA
WP_012752455.1\|1370707_1371283_-	hypothetical protein	NA	NA	NA	NA
WP_012752456.1\|1371315_1372071_+\|protease	trypsin-like serine protease	NA	NA	NA	NA
WP_003606880.1\|1372218_1373067_+\|protease	trypsin-like serine protease	I6WTR7	Cotesia_sesamiae_Mombasa_bracovirus	2.9e-06	23.4

DBSCAN-SWA_4

1958437 : 1995805

Leptospira_phage(22.22%)

integrase,transposase

attL 1992129:1992144|attR 1998718:1998733

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_085985459.1\|1958437_1959549_-\|transposase	IS3-like element ISMex1 family transposase	S5WIU1	Leptospira_phage	6.8e-48	40.7
WP_043766049.1\|1959682_1960516_-	DUF1738 domain-containing protein	A0A1V0EEV1	Caulobacter_phage	4.4e-52	42.3
WP_043766051.1\|1960959_1961766_+	hypothetical protein	NA	NA	NA	NA
WP_043766056.1\|1961823_1962267_-	PIN domain-containing protein	NA	NA	NA	NA
WP_043766059.1\|1962273_1962549_-	type II toxin-antitoxin system Phd/YefM family antitoxin	NA	NA	NA	NA
WP_043766062.1\|1962653_1963088_-	hypothetical protein	NA	NA	NA	NA
WP_043766064.1\|1963092_1963674_-	recombinase family protein	E5FFF9	Burkholderia_phage	4.2e-41	48.7
WP_082222825.1\|1964401_1964632_-	DUF2933 domain-containing protein	NA	NA	NA	NA
WP_012752685.1\|1964660_1965320_-	isoprenylcysteine carboxylmethyltransferase family protein	NA	NA	NA	NA
WP_158022369.1\|1965979_1968391_+	heavy metal translocating P-type ATPase	A0A218MNH6	uncultured_virus	2.7e-65	32.9
WP_082222826.1\|1968557_1970324_+	DUF3141 domain-containing protein	NA	NA	NA	NA
WP_012752688.1\|1970327_1971539_+	acetate/propionate family kinase	NA	NA	NA	NA
WP_012752689.1\|1971535_1972654_+	bifunctional enoyl-CoA hydratase/phosphate acetyltransferase	NA	NA	NA	NA
WP_012752690.1\|1972780_1973269_+	TetR/AcrR family transcriptional regulator C-terminal ligand-binding domain-containing protein	NA	NA	NA	NA
WP_085985459.1\|1973337_1974449_-\|transposase	IS3-like element ISMex1 family transposase	S5WIU1	Leptospira_phage	6.8e-48	40.7
WP_043766018.1\|1975882_1976836_-\|transposase	IS481-like element ISMex2 family transposase	NA	NA	NA	NA
WP_043766068.1\|1976919_1977204_-	hypothetical protein	NA	NA	NA	NA
WP_043766072.1\|1977706_1978438_-	ATP-binding protein	A0A2L1IVB6	Escherichia_phage	1.1e-33	32.5
WP_043766075.1\|1978437_1979937_-\|transposase	IS21-like element ISMex39 family transposase	NA	NA	NA	NA
WP_043766079.1\|1980106_1981660_+\|transposase	ISL3-like element ISMex26 family transposase	NA	NA	NA	NA
WP_050772659.1\|1981714_1982629_+	multicopper oxidase domain-containing protein	NA	NA	NA	NA
WP_012752691.1\|1982639_1983428_+	copper resistance protein B	NA	NA	NA	NA
WP_082222827.1\|1983736_1984033_+	hypothetical protein	NA	NA	NA	NA
WP_012752695.1\|1985648_1987067_+	copper oxidase	NA	NA	NA	NA
WP_012752696.1\|1987922_1988213_+	hypothetical protein	NA	NA	NA	NA
WP_043766087.1\|1989090_1989426_-	hypothetical protein	NA	NA	NA	NA
WP_012752698.1\|1989425_1990091_-	ParA family protein	M4HZI5	Mycobacterium_phage	1.5e-13	34.3
WP_012752700.1\|1991223_1992111_-	DNA adenine methylase	A0A0K1LM14	Caulobacter_phage	1.1e-61	48.0
WP_012752701.1\|1992107_1992740_-	hypothetical protein	NA	NA	NA	NA
1992129:1992144	attL	NA	NA	NA	NA
WP_043766091.1\|1993489_1993702_+	transcriptional regulator	NA	NA	NA	NA
WP_012752703.1\|1993698_1993866_+	hypothetical protein	NA	NA	NA	NA
WP_012752705.1\|1994482_1995805_+\|integrase	tyrosine-type recombinase/integrase	A0A291AUQ3	Sinorhizobium_phage	1.9e-41	31.4
1998718:1998733	attR	NA	NA	NA	NA

DBSCAN-SWA_5

3336249 : 3343517

Cronobacter_phage(16.67%)

tRNA

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_012753209.1\|3336249_3337521_-\|tRNA	tyrosine--tRNA ligase	K4F5T3	Cronobacter_phage	7.2e-54	37.7
WP_003599307.1\|3337661_3338795_+	anhydro-N-acetylmuramic acid kinase	NA	NA	NA	NA
WP_003599306.1\|3338804_3339428_+	DUF3578 domain-containing protein	NA	NA	NA	NA
WP_080577052.1\|3339421_3339712_-	putative addiction module antidote protein	A4JWV1	Burkholderia_virus	3.7e-14	44.0
WP_003599302.1\|3339711_3340014_-	type II toxin-antitoxin system RelE/ParE family toxin	A0A141GEX6	Brucella_phage	8.3e-25	60.2
WP_003599300.1\|3340135_3341236_+	chorismate synthase	A0A291AU41	Pandoravirus	1.4e-77	46.4
WP_003599298.1\|3341364_3342444_+	3,4-dihydroxy-2-butanone-4-phosphate synthase	A0A2H4PQS2	Staphylococcus_phage	1.2e-57	36.5
WP_043707076.1\|3342587_3343517_-	histone deacetylase family protein	A0A2K9KZC4	Tupanvirus	2.5e-35	32.7

DBSCAN-SWA_6

3894364 : 3915582

Leptospira_phage(33.33%)

integrase,transposase

attL 3887560:3887575|attR 3898479:3898494

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
3887560:3887575	attL	NA	NA	NA	NA
WP_043766330.1\|3894364_3895627_-\|integrase	tyrosine-type recombinase/integrase	B4UTU2	Rhizobium_phage	5.7e-59	36.6
WP_043766333.1\|3895898_3896459_-	hypothetical protein	NA	NA	NA	NA
WP_012753352.1\|3896458_3896707_-	hypothetical protein	NA	NA	NA	NA
WP_012753353.1\|3896706_3897573_-	hypothetical protein	NA	NA	NA	NA
WP_050772671.1\|3897750_3898767_-	hypothetical protein	NA	NA	NA	NA
3898479:3898494	attR	NA	NA	NA	NA
WP_012753356.1\|3898903_3899116_-	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_012753357.1\|3899112_3899592_-	hypothetical protein	NA	NA	NA	NA
WP_043766932.1\|3900606_3901479_+	DNA adenine methylase	R4JMC6	Burkholderia_phage	1.2e-52	43.8
WP_158022385.1\|3902093_3902237_-	hypothetical protein	NA	NA	NA	NA
WP_085985459.1\|3902684_3903795_+\|transposase	IS3-like element ISMex1 family transposase	S5WIU1	Leptospira_phage	6.8e-48	40.7
WP_076611539.1\|3904188_3905539_+\|transposase	IS3-like element ISMex16 family transposase	NA	NA	NA	NA
WP_012753360.1\|3906550_3907027_-	Rrf2 family transcriptional regulator	NA	NA	NA	NA
WP_015823806.1\|3907122_3908364_+	NO-inducible flavohemoprotein	NA	NA	NA	NA
WP_012753362.1\|3908418_3908862_+	PAS sensor domain-containing protein	NA	NA	NA	NA
WP_012753363.1\|3908879_3909674_+	5-formyltetrahydrofolate cyclo-ligase	NA	NA	NA	NA
WP_015823807.1\|3909886_3910579_+	GntR family transcriptional regulator	NA	NA	NA	NA
WP_043766018.1\|3910836_3911790_-\|transposase	IS481-like element ISMex2 family transposase	NA	NA	NA	NA
WP_158022386.1\|3911873_3912065_-	hypothetical protein	NA	NA	NA	NA
WP_043766344.1\|3912129_3912996_-	ATP-binding protein	U5N3V8	Enterobacteria_phage	1.3e-51	46.7
WP_080577080.1\|3912992_3914384_-\|transposase	IS21-like element ISMex13 family transposase	U5N3F9	Enterobacteria_phage	1.1e-44	34.1
WP_085985459.1\|3914471_3915582_+\|transposase	IS3-like element ISMex1 family transposase	S5WIU1	Leptospira_phage	6.8e-48	40.7

DBSCAN-SWA_7

4056895 : 4067665

Ralstonia_phage(10.0%)

integrase

attL 4046626:4046640|attR 4066207:4066221

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
4046626:4046640	attL	NA	NA	NA	NA
WP_043766946.1\|4056895_4058113_+\|integrase	site-specific integrase	A0A077KET4	Ralstonia_phage	2.0e-85	45.1
WP_043766949.1\|4058034_4058259_-	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_012753456.1\|4058326_4058632_-	hypothetical protein	A0A222YZB4	Escherichia_phage	5.1e-06	51.1
WP_158022392.1\|4058624_4058966_-	hypothetical protein	NA	NA	NA	NA
WP_015857135.1\|4058955_4059381_-	hypothetical protein	A0A076G7T6	Mycobacterium_phage	1.6e-13	39.2
WP_043766366.1\|4059435_4059672_-	hypothetical protein	NA	NA	NA	NA
WP_015857137.1\|4059722_4059983_-	hypothetical protein	F8TUU1	EBPR_podovirus	9.0e-12	50.6
WP_015857138.1\|4059987_4060539_-	hypothetical protein	NA	NA	NA	NA
WP_015857139.1\|4060535_4060892_-	hypothetical protein	NA	NA	NA	NA
WP_158022393.1\|4060895_4061648_-	hypothetical protein	NA	NA	NA	NA
WP_050772673.1\|4061649_4062792_-	hypothetical protein	Q8W6F5	Sinorhizobium_phage	4.5e-23	37.2
WP_158022394.1\|4062829_4063366_-	HNH endonuclease	A0A2H4IZP3	uncultured_Caudovirales_phage	1.9e-08	36.8
WP_015857143.1\|4063362_4063746_-	hypothetical protein	NA	NA	NA	NA
WP_015857144.1\|4063745_4064156_-	hypothetical protein	NA	NA	NA	NA
WP_015857145.1\|4064155_4064542_-	HNH endonuclease	NA	NA	NA	NA
WP_015857146.1\|4064534_4065335_-	HNH endonuclease	H2BCW0	Synechococcus_phage	3.2e-23	38.8
WP_015857147.1\|4065335_4065746_-	recombination protein NinB	I6R0N7	Salmonella_phage	1.1e-24	48.1
WP_015857149.1\|4066437_4067175_-	hypothetical protein	B0VK86	Azospirillum_phage	7.2e-30	35.2
4066207:4066221	attR	NA	NA	NA	NA
WP_043766369.1\|4067164_4067665_-	HNH endonuclease	M1HZB1	Paramecium_bursaria_Chlorella_virus	1.5e-10	36.6

DBSCAN-SWA_8

4075076 : 4133149

Escherichia_phage(18.18%)

transposase,tail,terminase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_043766380.1\|4075076_4076417_+	DNA cytosine methyltransferase	Q6V7R9	Burkholderia_virus	7.9e-59	38.9
WP_015857169.1\|4076413_4076728_+	hypothetical protein	NA	NA	NA	NA
WP_043766383.1\|4076801_4077149_+	hypothetical protein	NA	NA	NA	NA
WP_158022397.1\|4077148_4077880_+	hypothetical protein	Q94MV0	Myxococcus_phage	1.2e-16	43.4
WP_082222812.1\|4077876_4080186_+	DEAD/DEAH box helicase family protein	A0A2I7RTF8	Vibrio_phage	9.7e-73	39.5
WP_015857173.1\|4080166_4081105_+	toprim domain-containing protein	A0A0H5AWB1	Pseudomonas_phage	1.2e-45	36.0
WP_158022398.1\|4081134_4081446_+	hypothetical protein	NA	NA	NA	NA
WP_050772709.1\|4081497_4081899_+	hypothetical protein	A4JWM9	Burkholderia_virus	1.5e-34	61.2
WP_043766395.1\|4081942_4082698_+	hypothetical protein	NA	NA	NA	NA
WP_015857177.1\|4083179_4083548_+	DUF3307 domain-containing protein	A0A159B6H1	Gordonia_phage	2.5e-31	56.7
WP_015857178.1\|4083544_4083787_+	hypothetical protein	NA	NA	NA	NA
WP_015857179.1\|4083814_4084096_+	hypothetical protein	NA	NA	NA	NA
WP_015857180.1\|4084100_4084394_+	hypothetical protein	NA	NA	NA	NA
WP_015857181.1\|4084400_4085669_+\|terminase	PBSX family phage terminase large subunit	L7TP33	Pseudomonas_virus	2.8e-98	44.7
WP_015857182.1\|4085672_4086149_+	HNH endonuclease	J9SSY0	Escherichia_phage	1.4e-29	40.8
WP_015857183.1\|4086188_4086461_+	hypothetical protein	NA	NA	NA	NA
WP_015857184.1\|4086460_4088662_+	hypothetical protein	I3PUX6	Vibrio_phage	6.6e-95	35.7
WP_015857185.1\|4088710_4089550_+	hypothetical protein	NA	NA	NA	NA
WP_015857186.1\|4089775_4090996_+	hypothetical protein	A0A0E3M0Y6	Rhodoferax_phage	1.3e-47	33.9
WP_015857187.1\|4091661_4092132_+	hypothetical protein	NA	NA	NA	NA
WP_015857188.1\|4092138_4092495_+	hypothetical protein	NA	NA	NA	NA
WP_158022399.1\|4092652_4093453_+	hypothetical protein	NA	NA	NA	NA
WP_015857190.1\|4093455_4093998_+	hypothetical protein	NA	NA	NA	NA
WP_015857191.1\|4093997_4095428_+	hypothetical protein	NA	NA	NA	NA
WP_158022400.1\|4096209_4097688_+	hypothetical protein	A0A0E3JSB2	Rhodoferax_phage	3.8e-78	37.3
WP_015857194.1\|4097687_4098014_+	hypothetical protein	U6C692	Ralstonia_phage	1.2e-08	40.0
WP_015857195.1\|4098010_4098463_+	GNAT family N-acetyltransferase	NA	NA	NA	NA
WP_015857196.1\|4098464_4099169_+	hypothetical protein	NA	NA	NA	NA
WP_015857197.1\|4099168_4100536_+	hypothetical protein	NA	NA	NA	NA
WP_015857198.1\|4100525_4103180_+	cell wall hydrolase	L7TKC0	Rhizobium_phage	1.8e-14	32.2
WP_043766403.1\|4103161_4103347_-	hypothetical protein	NA	NA	NA	NA
WP_015857200.1\|4103546_4104896_+\|tail	phage tail protein	A0A1W6JT73	Escherichia_phage	8.6e-21	43.6
WP_158022401.1\|4104904_4106341_+	hypothetical protein	NA	NA	NA	NA
WP_015857201.1\|4106406_4107018_+	lysozyme	E5E3Z4	Acinetobacter_phage	7.1e-15	44.4
WP_050772678.1\|4108919_4109285_+\|transposase	IS200/IS605-like element ISMex20 family transposase	A0A1S5RHE3	Helicobacter_phage	7.2e-23	52.5
WP_003596282.1\|4109281_4109482_+	hypothetical protein	NA	NA	NA	NA
WP_003596281.1\|4109483_4109786_+	hypothetical protein	NA	NA	NA	NA
WP_003596280.1\|4109785_4110223_+	hypothetical protein	NA	NA	NA	NA
WP_015857202.1\|4110346_4110823_+	hypothetical protein	NA	NA	NA	NA
WP_162094038.1\|4110837_4111083_+	hypothetical protein	NA	NA	NA	NA
WP_158022402.1\|4111208_4111688_+	hypothetical protein	NA	NA	NA	NA
WP_158022403.1\|4111757_4112804_-	hypothetical protein	A0A0M4S6X1	Salmonella_phage	3.1e-50	38.6
WP_015857206.1\|4112973_4113240_-	hypothetical protein	NA	NA	NA	NA
WP_158022404.1\|4113477_4113711_+	hypothetical protein	NA	NA	NA	NA
WP_015857208.1\|4113754_4113997_-	hypothetical protein	NA	NA	NA	NA
WP_015857209.1\|4113993_4114212_-	hypothetical protein	NA	NA	NA	NA
WP_015857211.1\|4114471_4114711_-	hypothetical protein	NA	NA	NA	NA
WP_043766421.1\|4114714_4115380_-	serine/threonine protein phosphatase	B4UTT5	Rhizobium_phage	3.4e-47	42.0
WP_015857213.1\|4115631_4116069_-	hypothetical protein	NA	NA	NA	NA
WP_158022405.1\|4116302_4116851_+	hypothetical protein	NA	NA	NA	NA
WP_158022406.1\|4117235_4117400_-	hypothetical protein	NA	NA	NA	NA
WP_043766426.1\|4117509_4118604_+\|transposase	IS5-like element ISMex35 family transposase	NA	NA	NA	NA
WP_043766429.1\|4118672_4118912_-	hypothetical protein	NA	NA	NA	NA
WP_043766432.1\|4119062_4121051_-	right-handed parallel beta-helix repeat-containing protein	NA	NA	NA	NA
WP_015857218.1\|4121037_4121544_-	hypothetical protein	NA	NA	NA	NA
WP_158022407.1\|4122387_4125990_-	glycoside hydrolase family 99-like domain-containing protein	A0A1V0SDW6	Indivirus	1.0e-15	26.0
WP_015857219.1\|4126027_4126894_-	glucose-1-phosphate thymidylyltransferase RfbA	I7I009	Enterobacteria_phage	1.2e-92	55.9
WP_015857220.1\|4126909_4127800_-	dTDP-4-dehydrorhamnose reductase	NA	NA	NA	NA
WP_015857221.1\|4127802_4128861_-	dTDP-glucose 4,6-dehydratase	A0A1D7XFE8	Escherichia_phage	4.1e-87	49.0
WP_015857222.1\|4128994_4129546_-	dTDP-4-dehydrorhamnose 3,5-epimerase	A0A1D8EQH2	Escherichia_phage	2.3e-28	41.6
WP_043766436.1\|4130268_4131603_+\|transposase	IS1182-like element ISMex36 family transposase	NA	NA	NA	NA
WP_043765794.1\|4131805_4133149_+\|transposase	IS1380-like element ISMex4 family transposase	NA	NA	NA	NA

DBSCAN-SWA_9

4140943 : 4194086

Mycobacterium_phage(37.5%)

holin,tRNA,integrase,transposase

attL 4141350:4141368|attR 4203568:4203586

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_085985459.1\|4140943_4142054_+\|transposase	IS3-like element ISMex1 family transposase	S5WIU1	Leptospira_phage	6.8e-48	40.7
4141350:4141368	attL	NA	NA	NA	NA
WP_158022410.1\|4142078_4142426_-	PD-(D/E)XK nuclease family protein	NA	NA	NA	NA
WP_043766446.1\|4142695_4142980_-	hypothetical protein	NA	NA	NA	NA
WP_043765794.1\|4143450_4144794_+\|transposase	IS1380-like element ISMex4 family transposase	NA	NA	NA	NA
WP_015857232.1\|4145303_4145492_+	hypothetical protein	NA	NA	NA	NA
WP_015857233.1\|4145543_4145729_-	hypothetical protein	NA	NA	NA	NA
WP_009867550.1\|4145812_4147081_-\|transposase	IS256-like element ISMex3 family transposase	A0A2P1JQX9	Mycobacterium_phage	2.5e-91	45.7
WP_009867550.1\|4147855_4149124_+\|transposase	IS256-like element ISMex3 family transposase	A0A2P1JQX9	Mycobacterium_phage	2.5e-91	45.7
WP_043766449.1\|4149900_4151169_+\|transposase	IS256-like element ISMex3 family transposase	A0A2P1JQX9	Mycobacterium_phage	4.8e-90	45.4
WP_015857237.1\|4151332_4152220_-	YsnF/AvaK domain-containing protein	NA	NA	NA	NA
WP_050772681.1\|4152216_4152699_-	YsnF/AvaK domain-containing protein	NA	NA	NA	NA
WP_158022411.1\|4152695_4153664_-	PhnA-like protein	NA	NA	NA	NA
WP_015857242.1\|4154634_4154883_-	hypothetical protein	NA	NA	NA	NA
WP_015857243.1\|4156055_4156289_-	hypothetical protein	NA	NA	NA	NA
WP_012453265.1\|4157832_4158108_-	DUF2312 domain-containing protein	M4QRM3	Loktanella_phage	2.8e-11	46.4
WP_015857246.1\|4158297_4159122_-	hypothetical protein	NA	NA	NA	NA
WP_158022412.1\|4159361_4160213_-	hypothetical protein	NA	NA	NA	NA
WP_015857248.1\|4160310_4160547_-	AlpA family phage regulatory protein	NA	NA	NA	NA
WP_015857249.1\|4161003_4162152_-	hypothetical protein	NA	NA	NA	NA
WP_043766460.1\|4162206_4163397_-\|integrase	site-specific integrase	A0A077KET4	Ralstonia_phage	1.3e-81	46.9
WP_003600567.1\|4163859_4164042_+	DUF3606 domain-containing protein	NA	NA	NA	NA
WP_003604120.1\|4164284_4164500_+	hypothetical protein	NA	NA	NA	NA
WP_003604122.1\|4164824_4165352_+	hypothetical protein	NA	NA	NA	NA
WP_003604123.1\|4165397_4165619_-	hypothetical protein	NA	NA	NA	NA
WP_003604125.1\|4165842_4166058_-	hypothetical protein	NA	NA	NA	NA
WP_015857251.1\|4166181_4168017_-	allophanate hydrolase	NA	NA	NA	NA
WP_015857252.1\|4168328_4171856_-	urea carboxylase	NA	NA	NA	NA
WP_003605461.1\|4171860_4172481_-	urea carboxylase-associated family protein	NA	NA	NA	NA
WP_015857253.1\|4172495_4173302_-	DUF1989 domain-containing protein	NA	NA	NA	NA
WP_003605458.1\|4173466_4173838_-	cupin domain-containing protein	NA	NA	NA	NA
WP_003605456.1\|4173850_4175224_-	type III glutamate--ammonia ligase	NA	NA	NA	NA
WP_003605454.1\|4175225_4176026_-	creatininase family protein	NA	NA	NA	NA
WP_003605453.1\|4176022_4176964_-	ABC transporter ATP-binding protein	G3M9Y6	Bacillus_virus	1.2e-34	42.4
WP_015857254.1\|4176960_4178022_-	ABC transporter permease	NA	NA	NA	NA
WP_015857255.1\|4178032_4179043_-	ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_003606108.1\|4180044_4181373_+\|holin	betaine/proline/choline family ABC transporter ATP-binding protein	G3M9Y6	Bacillus_virus	2.7e-27	33.0
WP_015823926.1\|4181288_4182140_+	proline/glycine betaine ABC transporter permease	NA	NA	NA	NA
WP_003606104.1\|4182325_4183162_+	glycine betaine ABC transporter substrate-binding protein	NA	NA	NA	NA
WP_043766463.1\|4183242_4184592_+	hypothetical protein	NA	NA	NA	NA
WP_003606583.1\|4184768_4185800_-	GlxA family transcriptional regulator	NA	NA	NA	NA
WP_003606582.1\|4186236_4187490_+	sarcosine oxidase subunit beta family protein	NA	NA	NA	NA
WP_003606581.1\|4187509_4187842_+	sarcosine oxidase subunit delta	NA	NA	NA	NA
WP_043766465.1\|4187843_4190831_+	sarcosine oxidase subunit alpha family protein	NA	NA	NA	NA
WP_015857260.1\|4190823_4191414_+	sarcosine oxidase subunit gamma	NA	NA	NA	NA
WP_003607062.1\|4191556_4192918_+	L-serine ammonia-lyase	NA	NA	NA	NA
WP_003607061.1\|4193348_4193570_+	DUF1127 domain-containing protein	NA	NA	NA	NA
WP_003607059.1\|4193576_4194086_-\|tRNA	prolyl-tRNA synthetase associated domain-containing protein	NA	NA	NA	NA
4203568:4203586	attR	NA	NA	NA	NA

DBSCAN-SWA_10

4233188 : 4263019

Mycobacterium_phage(50.0%)

transposase

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_043766018.1\|4233188_4234142_-\|transposase	IS481-like element ISMex2 family transposase	NA	NA	NA	NA
WP_003606292.1\|4234265_4235438_+	GGDEF domain-containing protein	NA	NA	NA	NA
WP_003606293.1\|4235566_4236223_-	glutathione S-transferase family protein	NA	NA	NA	NA
WP_003606294.1\|4236573_4237788_+	polyhydroxyalkanoate depolymerase	NA	NA	NA	NA
WP_012254978.1\|4238222_4238540_+	30S ribosomal protein S21	NA	NA	NA	NA
WP_015857274.1\|4238639_4239029_-	response regulator	NA	NA	NA	NA
WP_003604305.1\|4239308_4240094_+	class II glutamine amidotransferase	NA	NA	NA	NA
WP_003604308.1\|4240245_4241037_+	TSUP family transporter	NA	NA	NA	NA
WP_003604310.1\|4241065_4242112_-	MaoC family dehydratase	NA	NA	NA	NA
WP_003604312.1\|4242306_4242597_-	YggT family protein	NA	NA	NA	NA
WP_009867550.1\|4243232_4244501_+\|transposase	IS256-like element ISMex3 family transposase	A0A2P1JQX9	Mycobacterium_phage	2.5e-91	45.7
WP_003597829.1\|4244541_4245039_+	HD domain-containing protein	NA	NA	NA	NA
WP_131473053.1\|4245828_4246095_+	hypothetical protein	NA	NA	NA	NA
WP_003597826.1\|4246323_4246524_+	hypothetical protein	NA	NA	NA	NA
WP_003597825.1\|4246547_4246880_-	hypothetical protein	NA	NA	NA	NA
WP_085985459.1\|4247243_4248355_-\|transposase	IS3-like element ISMex1 family transposase	S5WIU1	Leptospira_phage	6.8e-48	40.7
WP_015857281.1\|4248774_4250226_+	sensor domain-containing diguanylate cyclase	NA	NA	NA	NA
WP_043766483.1\|4250580_4252377_-	EAL domain-containing protein	NA	NA	NA	NA
WP_015857283.1\|4252773_4253082_-	hypothetical protein	NA	NA	NA	NA
WP_043766095.1\|4253711_4254665_-\|transposase	IS481-like element ISMex2 family transposase	NA	NA	NA	NA
WP_043766486.1\|4255912_4256977_+	hypothetical protein	NA	NA	NA	NA
WP_015857285.1\|4257022_4258126_+	hypothetical protein	NA	NA	NA	NA
WP_085985459.1\|4258325_4259436_+\|transposase	IS3-like element ISMex1 family transposase	S5WIU1	Leptospira_phage	6.8e-48	40.7
WP_082222814.1\|4259431_4260067_-	hypothetical protein	NA	NA	NA	NA
WP_193373938.1\|4260419_4260737_+	hypothetical protein	NA	NA	NA	NA
WP_015857287.1\|4260809_4261070_-	hypothetical protein	NA	NA	NA	NA
WP_015857288.1\|4261193_4261640_-	hypothetical protein	NA	NA	NA	NA
WP_009867550.1\|4261750_4263019_+\|transposase	IS256-like element ISMex3 family transposase	A0A2P1JQX9	Mycobacterium_phage	2.5e-91	45.7

DBSCAN-SWA_11

4874343 : 4905894

Leptospira_phage(57.14%)

integrase,transposase,protease

attL 4862311:4862328|attR 4908254:4908271

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
4862311:4862328	attL	NA	NA	NA	NA
WP_015857471.1\|4874343_4875513_-\|integrase	phage integrase	NA	NA	NA	NA
WP_015857473.1\|4875968_4876187_+	hypothetical protein	NA	NA	NA	NA
WP_015857474.1\|4876619_4876967_-	hypothetical protein	NA	NA	NA	NA
WP_158022415.1\|4877065_4877260_+	hypothetical protein	NA	NA	NA	NA
WP_015857475.1\|4877331_4877706_-	hypothetical protein	NA	NA	NA	NA
WP_015857476.1\|4877702_4878119_-	hypothetical protein	NA	NA	NA	NA
WP_158022416.1\|4878115_4878562_-	hypothetical protein	NA	NA	NA	NA
WP_015857478.1\|4878561_4879551_-	hypothetical protein	NA	NA	NA	NA
WP_158022417.1\|4879550_4880531_-	hypothetical protein	NA	NA	NA	NA
WP_085985459.1\|4881206_4882317_+\|transposase	IS3-like element ISMex1 family transposase	S5WIU1	Leptospira_phage	6.8e-48	40.7
WP_015857481.1\|4882379_4882847_-	hypothetical protein	NA	NA	NA	NA
WP_162094039.1\|4883228_4883897_-	phage antirepressor KilAC domain-containing protein	A0A2H4JDP7	uncultured_Caudovirales_phage	4.1e-32	42.1
WP_085985459.1\|4883979_4885091_-\|transposase	IS3-like element ISMex1 family transposase	S5WIU1	Leptospira_phage	6.8e-48	40.7
WP_158022418.1\|4885174_4885402_-	Arc family DNA-binding protein	NA	NA	NA	NA
WP_082222817.1\|4885492_4886029_+	Arc family DNA-binding protein	NA	NA	NA	NA
WP_015857483.1\|4886254_4886473_+	hypothetical protein	NA	NA	NA	NA
WP_158022419.1\|4886558_4886897_+	hypothetical protein	NA	NA	NA	NA
WP_158022420.1\|4886991_4887336_+	hypothetical protein	NA	NA	NA	NA
WP_043767041.1\|4887486_4888203_-	helix-turn-helix domain-containing protein	NA	NA	NA	NA
WP_015857485.1\|4888279_4888516_+	hypothetical protein	NA	NA	NA	NA
WP_043766556.1\|4888703_4888949_-	hypothetical protein	NA	NA	NA	NA
WP_015857486.1\|4889055_4889322_-	hypothetical protein	NA	NA	NA	NA
WP_043766558.1\|4889334_4889565_-	hypothetical protein	NA	NA	NA	NA
WP_015857488.1\|4889563_4889788_+	hypothetical protein	NA	NA	NA	NA
WP_158022421.1\|4889972_4890380_+	hypothetical protein	NA	NA	NA	NA
WP_015857491.1\|4890503_4890776_+	DUF837 domain-containing protein	NA	NA	NA	NA
WP_015857492.1\|4890768_4891047_+	hypothetical protein	NA	NA	NA	NA
WP_015857493.1\|4891133_4891481_+	hypothetical protein	NA	NA	NA	NA
WP_043766561.1\|4891482_4891755_+	hypothetical protein	A0A173G9J5	Propionibacterium_phage	3.1e-07	37.0
WP_085985459.1\|4891778_4892890_-\|transposase	IS3-like element ISMex1 family transposase	S5WIU1	Leptospira_phage	6.8e-48	40.7
WP_043766564.1\|4893353_4893653_-	hypothetical protein	NA	NA	NA	NA
WP_015857495.1\|4893874_4894534_+	hypothetical protein	NA	NA	NA	NA
WP_085985459.1\|4895499_4896610_+\|transposase	IS3-like element ISMex1 family transposase	S5WIU1	Leptospira_phage	6.8e-48	40.7
WP_043767043.1\|4896721_4896910_+	hypothetical protein	NA	NA	NA	NA
WP_015857496.1\|4896906_4897389_+	hypothetical protein	NA	NA	NA	NA
WP_158022422.1\|4898216_4898408_+	hypothetical protein	NA	NA	NA	NA
WP_015857501.1\|4898404_4898575_-	hypothetical protein	NA	NA	NA	NA
WP_015857502.1\|4900059_4900446_-	hypothetical protein	NA	NA	NA	NA
WP_015857503.1\|4900875_4901139_-	hypothetical protein	NA	NA	NA	NA
WP_003600131.1\|4901693_4902704_+	2-hydroxyacid dehydrogenase	M1HKI4	Acanthocystis_turfacea_Chlorella_virus	1.6e-64	42.7
WP_015857505.1\|4902732_4903686_-	LysR family transcriptional regulator	NA	NA	NA	NA
WP_003607233.1\|4903859_4904117_+	hypothetical protein	NA	NA	NA	NA
WP_003607231.1\|4904148_4904901_+	sulfite exporter TauE/SafE family protein	NA	NA	NA	NA
WP_043766569.1\|4904970_4905894_-\|protease	AprI/Inh family metalloprotease inhibitor	NA	NA	NA	NA
4908254:4908271	attR	NA	NA	NA	NA

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage