CRISPRimmunity

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Overview of predicted results

Overview of the results

Contig_ID	Contig_def	CRISPR array number	Contig Signature genes	Self targeting spacer number	Target MGE spacer number	Prophage number	Anti-CRISPR protein number
NC_012814	Bifidobacterium animalis subsp. lactis Bl-04, complete sequence	5 crisprs	WYL,cas3,DEDDh,csb3,csb2gr5,cas7,cas2,cas1	0	8	1	0

Results visualization

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CRISPR-Cas detection and classification

Crispr_ID: NC_012814_1

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_012814_1

183463-183848

Orphan

Consensus_repeat	Method
GGTCGGTTTTGCGGATGCTTCCG	CRISPRCasFinder

7 spacers

The CRISPR arrays of NC_012814_1

>merge|NC_012814|1|183463-183848|CRISPRCasFinder
GGTCGGTTTTGCGGATGCTTCCGTATGGCATGCCGTTTTCAGACTTCTTCGCGGTCGGTTTTGCGGATGCTTCCGAAAGCTATGCTGTTTTCAGACCATTCCGTGGCGCGTTTCTCGGATACCTCCGAGAGGCATGCCATTTTGGAGCCTTCTGGCAGTACGTTTCTCGGATGCTTCCGTACGCTGTGCTGCGGGGAAGACGGCCTGCGGTTTGGTTCTCGGATGCTTCCGTGAGATGTGCCTCTGATGGGGTGGTTTCTGGCCCATCTCTCGGATGCGTCCGTATGCTGTGCCGCTGCAGGGGTGGTTTGCGGTCCGTTGTGCGGATGCTTCCGTAGGCTGTGCCATTTTAGATTCCTTTGTGGCACGTTTCTCGGATGCTTCCG

>NC_012814|1|1|183463-183848|CRISPRCasFinder
GGTCGGTTTTGCGGATGCTTCCG	TATGGCATGCCGTTTTCAGACTTCTTCGC
GGTCGGTTTTGCGGATGCTTCCG	AAAGCTATGCTGTTTTCAGACCATTCCGT
GGCGCGTTTCTCGGATACCTCCG	AGAGGCATGCCATTTTGGAGCCTTCTGGC
AGTACGTTTCTCGGATGCTTCCG	TACGCTGTGCTGCGGGGAAGACGGCCTGC
GGTTTGGTTCTCGGATGCTTCCG	TGAGATGTGCCTCTGATGGGGTGGTTTCT
GGCCCATCTCTCGGATGCGTCCG	TATGCTGTGCCGCTGCAGGGGTGGTTTGC
GGTCCGTTGTGCGGATGCTTCCG	TAGGCTGTGCCATTTTAGATTCCTTTGT
GGCACGTTTCTCGGATGCTTCCG

Protein	Signature genes	Signature genes Name	Protein_function
NC_012814.1\|WP_004218470.1\|193395_195315_+\|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|224055
NC_012814.1\|WP_004218459.1\|184021_184723_+\|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|213222
NC_012814.1\|WP_004218453.1\|176884_177616_-\|hypothetical-protein	unknown	unknown	unknown
NC_012814.1\|WP_004268961.1\|187742_189287_+\|amino-acid-permease	unknown	unknown	gnl\|CDD\|224038
NC_012814.1\|WP_004218454.1\|177914_178076_+\|hypothetical-protein	unknown	unknown	unknown
NC_012814.1\|WP_004218457.1\|180924_181791_+\|iron-export-ABC-transporter-permease-subunit-FetB	unknown	unknown	gnl\|CDD\|377092
NC_012814.1\|WP_004218461.1\|184733_187688_+\|FtsX-like-permease-family-protein	unknown	unknown	gnl\|CDD\|223650
NC_012814.1\|WP_004218458.1\|181943_183440_+\|amino-acid-permease	unknown	unknown	gnl\|CDD\|224038
NC_012814.1\|WP_004218455.1\|178389_179655_+\|AGE-family-epimerase/isomerase	unknown	unknown	gnl\|CDD\|369267
NC_012814.1\|WP_004218451.1\|176165_176801_-\|YesL-family-protein	unknown	unknown	gnl\|CDD\|377412
NC_012814.1\|WP_004218469.1\|192730_193324_+\|MarR-family-transcriptional-regulator	unknown	unknown	gnl\|CDD\|197670
NC_012814.1\|WP_004218450.1\|174853_175882_+\|LacI-family-DNA-binding-transcriptional-regulator	unknown	unknown	gnl\|CDD\|224525
NC_012814.1\|WP_004218449.1\|173859_174597_+\|hypothetical-protein	unknown	unknown	unknown
NC_012814.1\|WP_004218467.1\|189895_191617_-\|ABC-transporter-permease	unknown	unknown	gnl\|CDD\|223650
NC_012814.1\|WP_072633038.1\|189540_189999_-\|ABC-transporter-permease	unknown	unknown	unknown
NC_012814.1\|WP_004218471.1\|195386_197222_+\|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|224055
NC_012814.1\|WP_004218464.1\|189298_189544_-\|FtsX-like-permease-family-protein	unknown	unknown	gnl\|CDD\|226957
NC_012814.1\|WP_004218456.1\|180182_180923_+\|ATP-binding-cassette-domain-containing-protein	unknown	unknown	gnl\|CDD\|182331
NC_012814.1\|WP_004218448.1\|172047_173430_+\|beta-glucosidase	unknown	unknown	gnl\|CDD\|274539
NC_012814.1\|WP_004218468.1\|191613_192036_-\|ATP-binding-cassette-domain-containing-protein	unknown	unknown	gnl\|CDD\|224059

Protein	Function_ID	Function_description	E-value
NC_012814.1\|WP_004218470.1\|193395_195315_+\|ABC-transporter-ATP-binding-protein	gnl\|CDD\|224055	COG1132, MdlB, ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms].	1.18215e-139
NC_012814.1\|WP_004218459.1\|184021_184723_+\|ABC-transporter-ATP-binding-protein	gnl\|CDD\|213222	cd03255, ABC_MJ0796_LolCDE_FtsE, ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and cell division protein. This family is comprised of MJ0796 ATP-binding cassette, macrolide-specific ABC-type efflux carrier (MacAB), and proteins involved in cell division (FtsE), and release of lipoproteins from the cytoplasmic membrane (LolCDE). They are clustered together phylogenetically. MacAB is an exporter that confers resistance to macrolides, while the LolCDE system is not a transporter at all. An FtsE null mutants showed filamentous growth and appeared viable on high salt medium only, indicating a role for FtsE in cell division and/or salt transport. The LolCDE complex catalyzes the release of lipoproteins from the cytoplasmic membrane prior to their targeting to the outer membrane.	2.55179e-99
NC_012814.1\|WP_004268961.1\|187742_189287_+\|amino-acid-permease	gnl\|CDD\|224038	COG1113, AnsP, Gamma-aminobutyrate permease and related permeases [Amino acid transport and metabolism].	1.70709e-147
NC_012814.1\|WP_004218461.1\|184733_187688_+\|FtsX-like-permease-family-protein	gnl\|CDD\|223650	COG0577, SalY, ABC-type antimicrobial peptide transport system, permease component [Defense mechanisms].	1.32837e-12
NC_012814.1\|WP_004218458.1\|181943_183440_+\|amino-acid-permease	gnl\|CDD\|224038	COG1113, AnsP, Gamma-aminobutyrate permease and related permeases [Amino acid transport and metabolism].	2.07775e-179
NC_012814.1\|WP_004218455.1\|178389_179655_+\|AGE-family-epimerase/isomerase	gnl\|CDD\|369267	pfam07221, GlcNAc_2-epim, N-acylglucosamine 2-epimerase (GlcNAc 2-epimerase). This family contains a number of eukaryotic and bacterial N-acylglucosamine 2-epimerase (GlcNAc 2-epimerase) enzymes (EC:5.3.1.8) approximately 500 residues long. This converts N-acyl-D-glucosamine to N-acyl-D-mannosamine.	5.66098e-127
NC_012814.1\|WP_004218451.1\|176165_176801_-\|YesL-family-protein	gnl\|CDD\|377412	pfam04854, DUF624, Protein of unknown function, DUF624. This family includes several uncharacterized bacterial proteins.	7.22333e-11
NC_012814.1\|WP_004218469.1\|192730_193324_+\|MarR-family-transcriptional-regulator	gnl\|CDD\|197670	smart00347, HTH_MARR, helix_turn_helix multiple antibiotic resistance protein.	1.25581e-13
NC_012814.1\|WP_004218450.1\|174853_175882_+\|LacI-family-DNA-binding-transcriptional-regulator	gnl\|CDD\|224525	COG1609, PurR, Transcriptional regulators [Transcription].	2.91291e-76
NC_012814.1\|WP_004218457.1\|180924_181791_+\|iron-export-ABC-transporter-permease-subunit-FetB	gnl\|CDD\|377092	pfam03649, UPF0014, Uncharacterized protein family (UPF0014).	8.05493e-81
NC_012814.1\|WP_004218467.1\|189895_191617_-\|ABC-transporter-permease	gnl\|CDD\|223650	COG0577, SalY, ABC-type antimicrobial peptide transport system, permease component [Defense mechanisms].	4.61117e-28
NC_012814.1\|WP_004218471.1\|195386_197222_+\|ABC-transporter-ATP-binding-protein	gnl\|CDD\|224055	COG1132, MdlB, ABC-type multidrug transport system, ATPase and permease components [Defense mechanisms].	0
NC_012814.1\|WP_004218464.1\|189298_189544_-\|FtsX-like-permease-family-protein	gnl\|CDD\|226957	COG4591, LolE, ABC-type transport system, involved in lipoprotein release, permease component [Cell envelope biogenesis, outer membrane].	0.00288599
NC_012814.1\|WP_004218456.1\|180182_180923_+\|ATP-binding-cassette-domain-containing-protein	gnl\|CDD\|182331	PRK10247, PRK10247, putative ABC transporter ATP-binding protein YbbL; Provisional.	4.31445e-39
NC_012814.1\|WP_004218448.1\|172047_173430_+\|beta-glucosidase	gnl\|CDD\|274539	TIGR03356, BGL, beta-galactosidase.	0
NC_012814.1\|WP_004218468.1\|191613_192036_-\|ATP-binding-cassette-domain-containing-protein	gnl\|CDD\|224059	COG1136, SalX, ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms].	4.3829e-49

>NC_012814.1|WP_004218458.1|181943_183440_+|amino-acid-permease
MSASHGAGERNADPQQLHKSLKNRHIQLIALGGAIGTGLFYGSSESIALAGPSILLAYVIGGAAIFVIVRAMSEMSVEEPKAGAFSYYASRYWSKRAGFISGWNYWFNYVLVSMVELAVVGSFVNYWFPNIPQWASAAFFLVLITLLNLFGVSEFGEFEFWFALIKIVAVIAMIAGGLWVIVANLPTDSGVRASFANWFTVDGGFFPHGAMSRAADGHWDGLLMALVVVMFSFGGTELIGVTAGEVENPSKTIPRATNGIIWRILVFYVAALGIIMAVVPWDRIDGKMSPFVQIFDSVGVPVAAGILNFVCLTAVMSVYNSALYSNSRMLFSLARQGNAPAYLGRVNKRGVPVAGVLTSAAVTVVAVVVVFLWPQFAFNYLMSIATIAAIINWTMIMITEMLFRRRVAAGDGPGELNGLRGAEALAKIRFKLPGWNWTPYVIIAFLAMVAVLMCFSPSYRIALIAGVIWLAVLFAAYAITSRASAKRDAKTVLDSTRK
>NC_012814.1|WP_004218457.1|180924_181791_+|iron-export-ABC-transporter-permease-subunit-FetB
MQQYFAIDNWGLLIAVLMVCIAAGVSALMKLGVAKSLLWATARSLVQLLAMGFILEYVIRAQNVWLVIGLIVVMLVAAAQITMSRAKGIPKGLVPLVLLSLAVTMLLMLALVGELVIRPNPWYSPQLIIPLTGMLLGNTVSALALGLSRFFNSMRERYEEVNTLLALGATPWEAAKPSITSSITLGLLPSIAMLASSGIVTIPGMMSGQIIAGQNPVNAAKYQFVILAAVSALTLLADSIILALVYKRCFISYDRYFVPPARDSVSTLDRIRRQAAERANRGPESAGE
>NC_012814.1|WP_004218456.1|180182_180923_+|ATP-binding-cassette-domain-containing-protein
MGSMSSAHDFHATGVTAVVNNDAGGTRTIFKDLSFAVHGGEIVDITGPSGSGKSTLLTSFARLNVNTTGKFVLDGVDSDTLSPQQWRERVAYLPQTSVLIGDNVADAIRLPWSLKIRVSQDHEAAEQKLPDSLIRSTLDSLGCDDIDLARAVQDLSGGQAARVSLTRTLLTHPGVLLADEVDAGLDEENADKVADILRKAADNGTAVVRIRHRKPDGRANRIMVLANGTISPLKTAQSAPSTHTEV
>NC_012814.1|WP_004218455.1|178389_179655_+|AGE-family-epimerase/isomerase
MANTDPKYQIGTPENKKFLDISRDNLIAFGRRFPAVDGSSYWLGDDGTPWKDRNRATWITCRMTHVYSLATLLGVDGAAELVDDGIRGLRGVLHDEEHDGWYAEITPDICHMPTKQAYAHAFVLLAASSALLAGRPGAKELLEQAENVYLTKFWDDKIGLSVDTWDTDFAELDTYRGLNANMHSVEACLAVADVTGDESWRTRAGRIIEHVLKWAEENNWRIPEHFNSDWEPELEFNADKPDDQFKPYGATPGHGIEWARLITQYALSVYGKDGVLNGDGKKYLDAAEHLFNRAVEDAWNADGAPGIVYTTDWDGKPVVHDRMHWTLAEGVNTAATLYHVTGKKEYADWYATFLEYIDTYLMDHKNGSWFHQLNRENEVIDTVWPGKSDLYHATQAMMIPLRDPALSIAPATKKGVEEGLN
>NC_012814.1|WP_004218454.1|177914_178076_+|hypothetical-protein
MYDEGPHIVLRRDGVCIVAKTPDGDMPQIEYWGRDFAFDTAGDALRQLDMRAI
>NC_012814.1|WP_004218453.1|176884_177616_-|hypothetical-protein
MEGKQPKLTPEQREAIDTLSSTPQYQGESKIKIFMKIPAKDKAAYSRTHFLVPLLAAVIVIALGTFVIVRLVSPVPRPALYAAAVSGSTPMGEADKLKDDYAKKLGKDVIIDDYFDMNKDGLSKLQTMIGNEQIDVVIAPHDVFAKLASFGYFDNLKTTLPAAEYAKVGKYAMAFHGFDDSRVTDAIDESGSGQGKSEPYGLLLEHAPRWDRIEGADDDALVGIAANTQQLDTAKNFIQYLYN
>NC_012814.1|WP_004218451.1|176165_176801_-|YesL-family-protein
MIAGGIFRQDNPYNTVMNRIGDIAMLSVAWFVCCLPVVTIGVSTAAACEVAREMQEDRDNGIFKGFWRAIKRRFGTGMLLTLFLGVLIALGAFDLWWISRSMAGDMASVLYGVTLAVFIIVAMLFAFLLPLSGRSKLSAGEQIKQSAKLATMKPFIALVVAAIYALPIVLLATLPSAVMWVPLVWCIFGGGASAWAQMWLIRRAFDLQPQD
>NC_012814.1|WP_004218450.1|174853_175882_+|LacI-family-DNA-binding-transcriptional-regulator
MVAQKAKVTIFDVAKASGVSSSAVSYALNGKPGVSDATREKVLQVARKLGWRPNGAAQSLAQSRTRRIGLVLGYDPQLLSAEPYIMRLISGLGSALEERDYSLLVRMSMDDDDEVSILEDWIATGNVDALLLLNLEIGDPRIELMKNNPQMPCLALADSSLTSGLPTLMSDDAAASGTMIRHLALFGHKNIARVAGPEELGHSYIRDAAFSEITTELGMRYRCLHTDYTPESGAEATKRLLSVEPRPTAIIYDNDVMALAGESVASVKGVRVPEDLSIISWGDSFMNVAAHPPITALSRNILESGRLAAQLMLKLIDGEDVENVEEPPYELIERASTAPAAQ
>NC_012814.1|WP_004218449.1|173859_174597_+|hypothetical-protein
MKVKKIAAIALASACAFSMAAVDFNGHRKPVWYASRDFFAPRLATIQPRTSEEYRETHSWEGVKVDADHLELIVLNDTNEPYKGSWAVNRVDFDGNVLATQQIDDVELDAASHKGFPLNEEIVDFGDANNELIVAVPSDDSFARVIYNPAEILTQELDAPADAFTTKAKRTADGVELTVTANDYVRDLFCMVGKVDDKATVEEGLVSLLPGESVTFHIGTDYAGDPADFAAANVLRSANDLKRDF
>NC_012814.1|WP_004218448.1|172047_173430_+|beta-glucosidase
MTMTFPKGFQFGTATAAYQIEGAVDEDGRTPSIWDVFSHAPGRVLNGDTGDKADDFYHRWQDDLKLVRDLGVNAYRFSIGVPRVIPTPDGKPNEKGLDFYERIVDQLLEYGIDPIVTLYHWDLPQYLNEDPYRDGWLNRETAFRMAEYAGIVAKRLGDRVHTYTTLNEPWCSAHLSYGGTEHAPGLGAGPLAFRAAHHLNLAHGLMCEAVRAEAGAKPDLSVTLNLQVNRGDADAVHRVDLIANRVFLDPMLRGYYPDELFAITKGICDWDFVHDGDLKLINQPIDVLGLNYYSTNLLAMSDRPQFPQSTEASTAPGASDIDWLPTDGPHTQMGWNIDPDALYNTLVRLNDDYDHIPLVVTENGMACPDEVEVGPDGVKMVHDDDRIDYLRRHLEAVHRAIEEGANVIGYFVWSLMDNFEWAFGYDRRFGLTYVDYDTEERIRKDSYNWYRNFIAEHSAK
>NC_012814.1|WP_004218459.1|184021_184723_+|ABC-transporter-ATP-binding-protein
MAYIEFNDVVKEYPAGSSSIRALDGASFAADEGELSVILGQSGAGKTTALNILGGMDTATSGRVIVGGRDITDLNHHDLVTYRRNDIGFVFQFYNLIPNLTALENVELASQICTDHFDPAQTLAKVGLADRLGNFPAQLSGGEQQRVSIARALAKKPKLLLCDEPTGALDYETGKEVLQLLQDICRTERMTVLIVTHNSALAPMAHKVIRFRSGKVTSQETNEHPVPISQIEW
>NC_012814.1|WP_004218461.1|184733_187688_+|FtsX-like-permease-family-protein
MARRKGVPVGDADVHAQIADSGSLHAEHGHARAVGSAFLLDTMRSGLHAWKPFLSILIITMLGVAVLTGIYAGCRDTFAAANRFYRAQGLHDVQVISTMGLTDADVDALRQVEGVEQAQGMRMIRVKVADGDGKQLNATLEEPASGSPAALDRPYVNEGWLPSKPGEVAVTAQFTHDTHKKLGDTVEVAADGEDDGTHGLKIVGIVTDPSDLTNPGGYSGSAFRSSVTNDYTFYTAPDGIQRTFVKADGTPIAAADPKVYGSIVLRLDDAENEDAFTASYDDLVSGTVKRIENGVQAKREQARRNALVEEAQNKLDAEKKKAFDQIDAAQAKLDAQRRQLDDQLKQLDAQTAQIPVGVPEPAQLAEAQRQWAAADTKLREAQQAIDTQRNEAFSAFAAEQQKVDGIATPRWYVQSRSALAGFSSLKSDISSIESLGKAFPIVFLVVAVMMSLTTMSRLVEEDRGLVGTYLGLGYGRIAITLRYALFALLACLIGGGLGLLIGFLGIPAFLLVVIRGLYAIPDLRLEYDWLYGSLGVLLFVVGVLGAALIASVREMRQMPAALMRPKAPKAGSRILLERVRPLWSRMSFLNKVTARNIFRFKARLIMTVGGVAGCTALILCGLAINDTVAALGPNQYRGVDQYDMLAVANDGDEQALRKKLVSDGTTTAIMETRIENGEITNANDRGTNVQLTVVPQRQLGELNTMFDLQPAQGDSLLGWVHGGNRNQPVRLDNSGIIVAQSAAQSLGIKAGSEVTLRGDGTQPHKVKVAQVTRSLIGAEAFISEDLYHQLFPAQQAGDGGTEPAITWNAVYAKLKGSDSEQSEYVQHLKNEATVMSATSCAQQAEDFKFDLMGAVVALIVALAGSLALVVLFTLAHTNVSERLREMATLKVLGFYGREVHHYVNREMMVLTVMGIVIGLPLGRWVSGLLTNALNMPGIYFEVHISWWSYIITVVATLAFAWLVQLFVNPVLDRIDPVSSLKSVE
>NC_012814.1|WP_004268961.1|187742_189287_+|amino-acid-permease
MSDVQQPAEPHETPHEEEVNASLETLDKDNEMERGLSNRHVQFIAIGGAIGTGLFLGSGKSINLAGPNIIFVYILVGGIMFLMMRAIGELMYRDPSQHTFINFIRFYLGDGWGKFALWSYWIVLILIGMTEITAVGQYCVTFFRTLGYDVSAWKGLIELGFLLLLVMINLIAVKAFGEAEFWFSMIKITLIVAMIATAVIMLVCGFKYNAVQVPGQDHVSPAGSVTLDNLTRGFSLAPNGWLAFLMSFQMVFFAYEMIEFMGVTVSETKNPRKVLPKAINGIIVRVLIFYVGALLAIMTIVPWRNFRPNKDGSFASPFIMVFEYAGANWAAALVFFVVVTAAASSLNSLLYSAGRHLYEIAEDSPSPAIAKLGVVSKTKVPARAIIASAILVLLSPVIEMIPRVSGAFVMFSSASSAVIIFIYILTMIAHYRYRNSPQFMANGFRMPAYRVLNPLTTAFFVFIYCTLFIGADTRGPAIAGLVWLVVFGGYCVLHERFQNRDLKQSIDSAGDAHA
>NC_012814.1|WP_004218464.1|189298_189544_-|FtsX-like-permease-family-protein
MIAIESVILSVFGTVLGILVGLGAGVVVRQAYRDNGLSTMSIPWLQLLGFLGAAILVGLIASISPASRALKKPVLEAVASD
>NC_012814.1|WP_072633038.1|189540_189999_-|ABC-transporter-permease
MLASVSDMIDDNLHADYVLVSAALSQSVSPKAVNDVKHTAGVGATTAVRTLPTVKLMQANEQFTAMAVDRELLDAMYPATHQEGDAAQAIEHGEIAVGRKVADSNGYAIGSTVEMESKNIGIDEAATKQAIAAYEQQVGEQVSVHRTGRYVA
>NC_012814.1|WP_004218467.1|189895_191617_-|ABC-transporter-permease
MIRIGLRDAKAHFHRLVMSIIAIALGVSFVVGSFCFRSMLNDQVTQLMGTNSDHDVYVRGTTEEQNDSSFATSGPISSGTSYNKIDTSLVTQIEQVKGIDNVSPPERTIGATLLDHDGNAVVTTGAPTLMISASSEHPWRAANFIAGTYATGEHEIALSQDAAKKAGLQVGDTTRLIVNGEPHTMKVSGVFTTQTAELGVLIILAQPALVNQLMQLQGEDTSKVDKIGVYGNRTTPLTVQKQHQLADRINKALPKDSKAHAVTGQSVRDEATKSTQESLGFVQPLILIFAVIALFVGAFIIANTFTMIVRDSMRGYALLRSVGASPAQVFFSVVIQALILGVIGSVLGVLLGWGLIELIDWGLSKGGFPLSGSPTPSPTAVAVGFMVGVVVTVIGSAIPARTAATAPPIQAMNETMNPEKPVTARGWIGAGMVAFGALCWLLCWLLAAKKVSWAWLTTVGTGWLLGLGGVCTAGGVIVLAPALVTGAAKVLGWLPSRIPGDRHAGHPQHRPHETSHRQHGRRPVRGRGNRQLPERARLVNARLGERYDRRQSSCRLCARLRRALAIRLAEGRQ
>NC_012814.1|WP_004218468.1|191613_192036_-|ATP-binding-cassette-domain-containing-protein
MDWFDKVVSVVKLQNRLDHRPSQLSGGQQQRVACARAIMERPSVIFADEPTGNLDSRSSHEVFEFLRMCVREYGQTIVMVTHDPRAASFADRVLVLSDGSIVQDLDHPSYDDILAVFAQDDDPQNGPVEVESATARSAEQ
>NC_012814.1|WP_004218469.1|192730_193324_+|MarR-family-transcriptional-regulator
MDYQLEAVHELMFAMWASRSKATRSFERGAQGEMFVLRELSFQGARTPSQLAQAMGATSGRISSILASLTKKGWIVRTGDPQDRRSVVVELSDEGRRAVRQRSDRLIENLSWVFSQMGERRTREFVGLLSEFMTYLSICEPDGSYPTVEQVEEAFERRARLHERMREMVRNGEQWHGSCRPHDAPSSNDADVDRPVQ
>NC_012814.1|WP_004218470.1|193395_195315_+|ABC-transporter-ATP-binding-protein
MIRIMKYLSKTEIGQLVLSLVTIVGQVYFDLELPSYMSQITRLVETPGSQMRDIWIAGGKMLLVSLGSLACAVITGYFAARVAASFGQRLRSLEFRKVESFGPSEMHRFSTASLITRSTNDITQIQMFITMGLQMLIKAPIMAVWAVCKIAGEGFEWTLATGIAVAILIISIAVLMVLVMPKFKAMQQLTDDINLVTRENLTGMRVVRAYNAQDYQEGKFERANSNLTNTQLFTNRAMSVMMPLMGTIMNGLSLAIYWIGAYLIQDAGLTDKLTLFSNMVVFSSYAMQVVMSFLLMSMVFVLWPRADVSAHRVLEVLDTDPLVKSGTAERGLTVQEAKQRGIITPAERARYADDLELAGEIEFRDVSFTYPDSREAMLEHISFTANRGDTVAIIGSTGSGKSSLINLVPRFYDATDGEVLVDGVNVREYDLKTLRDKIGYVPQRSFLFKGTVESNVSYGDRPDEPEDVPVIDVSRMSGRKAEREFLKAGEARELTAQEANRVREASDIAQATEFVSKMPKGFQSPIAQGGTNVSGGQKQRLSIARAVYRDPEILIFDDSFSALDFKTDREVRDALKETAKDATKLIVAQRVGTIMDADCILVLEDGKVVGQGTHRELLETCEVYQEIAKSQLSEEELSA
>NC_012814.1|WP_004218471.1|195386_197222_+|ABC-transporter-ATP-binding-protein
MGHGRAGAPVEKADDFGGALKELMRFSKRYIPAIVIALILGVGGAICQIIGPDYLGDMTDEITKGLPALVHGKPVLRSIDMTAVTRIGWTLVALYVGYALLSYVQSWMMATVTQRTAQRLRAAIDVKMNKLPLKYFDEHSTGDVMSRITNDVDAVGQTLGQSLGTLISSVTLFVGSLVMMFANNWILALCAVGATLLGMVLMLVVMRFSQKYFVKQQMALGDVNGHVEEMYSGHTVVKAFGGEADAIRRFERYNNDLYDSGWKSQFISGLMMPMMNLVGNLGYVVVCVVGAALAMNGSIEFGVIVAFMLYIRLFTQPLSQFAQAFQNLQRCAAGSERVFTFLDEPELADESDKQPLLGYGSNGEITPVEGRVSFEHVKFGYEPNKLVIHDFSADVEPGQKVAIVGPTGAGKTTMVNLLMRFYEIAGGKISIDGIDTKSVPRWNVHDQFSMVLQDTWVFNGTVRENVAYAKEDVTDEQVVAACRAVGLDRYIRSLPNGYDTVLDESATLSQGQKQLLTIARAMVQDSPILILDEATSSVDTRTEELIQTAMDKLTEGRTSFVIAHRLSTIRDADMILVMRDGDIVERGTHEELLAKHGFYADIYNAQFTLAQ

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Crispr_ID: NC_012814_2

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_012814_2

219240-219323

Orphan

Consensus_repeat	Method
TTTCCGTCTCTTTTTACGCAGAA	CRISPRCasFinder

1 spacers

The CRISPR arrays of NC_012814_2

>merge|NC_012814|2|219240-219323|CRISPRCasFinder
TTTCCGTCTCTTTTTACGCAGAAAGGGCCGGTTTGCGTAATTGGGGACATCGCTGGGCTGCTTTCTGTCTCTTTTTACGCAGAA

>NC_012814|2|2|219240-219323|CRISPRCasFinder
TTTCCGTCTCTTTTTACGCAGAA	AGGGCCGGTTTGCGTAATTGGGGACATCGCTGGGCTGC
TTTCTGTCTCTTTTTACGCAGAA

Protein	Signature genes	Signature genes Name	Protein_function
NC_012814.1\|WP_004218495.1\|221813_223109_+\|ammonium-transporter	unknown	unknown	gnl\|CDD\|223083
NC_012814.1\|WP_004218488.1\|214554_215436_-\|patatin-family-protein	unknown	unknown	gnl\|CDD\|132847
NC_012814.1\|WP_004218499.1\|226277_227657_+\|replicative-DNA-helicase	unknown	unknown	gnl\|CDD\|273206
NC_012814.1\|WP_004218483.1\|209807_210449_+\|MptD-family-putative-ECF-transporter-S-component	unknown	unknown	gnl\|CDD\|370580
NC_012814.1\|WP_004218484.1\|210445_211186_+\|energy-coupling-factor-transporter-transmembrane-protein-EcfT	unknown	unknown	gnl\|CDD\|223692
NC_012814.1\|WP_004218489.1\|215571_216339_+\|hypothetical-protein	unknown	unknown	unknown
NC_012814.1\|WP_004268977.1\|217559_219128_+\|C69-family-dipeptidase	unknown	unknown	gnl\|CDD\|335383
NC_012814.1\|WP_004218486.1\|212775_214359_-\|ZinT/AdcA-family-metal-binding-protein	unknown	unknown	gnl\|CDD\|370371
NC_012814.1\|WP_004218497.1\|223759_225586_+\|nucleotidyltransferase-domain-containing-protein	unknown	unknown	gnl\|CDD\|235123
NC_012814.1\|WP_004218502.1\|230187_230535_+\|phasin-family-protein	unknown	unknown	gnl\|CDD\|226447
NC_012814.1\|WP_004218485.1\|211238_212726_+\|ATP-binding-cassette-domain-containing-protein	unknown	unknown	gnl\|CDD\|213193
NC_012814.1\|WP_004218501.1\|229330_230080_+\|glutamine-amidotransferase	unknown	unknown	gnl\|CDD\|225974
NC_012814.1\|WP_004218482.1\|206745_209514_-\|YhgE/Pip-domain-containing-protein	unknown	unknown	gnl\|CDD\|224428
NC_012814.1\|WP_004218491.1\|216518_217229_-\|hypothetical-protein	unknown	unknown	unknown
NC_012814.1\|WP_004218481.1\|204550_206749_-\|YhgE/Pip-domain-containing-protein	unknown	unknown	gnl\|CDD\|224428
NC_012814.1\|WP_004218496.1\|223110_223449_+\|P-II-family-nitrogen-regulator	unknown	unknown	gnl\|CDD\|366157
NC_012814.1\|WP_004218494.1\|220153_221554_+\|signal-recognition-particle-docking-protein-FtsY	unknown	unknown	gnl\|CDD\|236686
NC_012814.1\|WP_004218498.1\|225946_226219_+\|helix-turn-helix-transcriptional-regulator	unknown	unknown	gnl\|CDD\|238045
NC_012814.1\|WP_004218500.1\|227753_229262_+\|Mur-ligase-family-protein	unknown	unknown	gnl\|CDD\|377986
NC_012814.1\|WP_004218503.1\|230643_232794_+\|AarF/ABC1/UbiB-kinase-family-protein	unknown	unknown	gnl\|CDD\|223733

Protein	Function_ID	Function_description	E-value
NC_012814.1\|WP_004218488.1\|214554_215436_-\|patatin-family-protein	gnl\|CDD\|132847	cd07208, Pat_hypo_Ecoli_yjju_like, Hypothetical patatin similar to yjju protein of Escherichia coli. Patatin-like phospholipase similar to yjju protein of Escherichia coli. This family predominantly consists of bacterial patatin glycoproteins, and some representatives from eukaryotes and archaea. The patatin protein accounts for up to 40% of the total soluble protein in potato tubers. Patatin is a storage protein, but it also has the enzymatic activity of a lipid acyl hydrolase, catalyzing the cleavage of fatty acids from membrane lipids. Members of this family have also been found in vertebrates.	1.81216e-110
NC_012814.1\|WP_004218499.1\|226277_227657_+\|replicative-DNA-helicase	gnl\|CDD\|273206	TIGR00665, DnaB, replicative DNA helicase. This model describes the helicase DnaB, a homohexameric protein required for DNA replication. The homohexamer can form a ring around a single strand of DNA near a replication fork. An intein of > 400 residues is found at a conserved location in DnaB of Synechocystis PCC6803, Rhodothermus marinus (both experimentally confirmed), and Mycobacterium tuberculosis. The intein removes itself by a self-splicing reaction. The seed alignment contains inteins so that the model built from the seed alignment will model a low cost at common intein insertion sites. [DNA metabolism, DNA replication, recombination, and repair].	0
NC_012814.1\|WP_004218483.1\|209807_210449_+\|MptD-family-putative-ECF-transporter-S-component	gnl\|CDD\|370580	pfam09605, Trep_Strep, Hypothetical bacterial integral membrane protein (Trep_Strep). This family consists of strongly hydrophobic proteins about 190 amino acids in length with a strongly basic motif near the C-terminus. It is found in rather few species, but in paralogous families of 12 members in the oral pathogenic spirochaete Treponema denticola and 2 in Streptococcus pneumoniae R6.	3.6075e-52
NC_012814.1\|WP_004218484.1\|210445_211186_+\|energy-coupling-factor-transporter-transmembrane-protein-EcfT	gnl\|CDD\|223692	COG0619, CbiQ, ABC-type cobalt transport system, permease component CbiQ and related transporters [Inorganic ion transport and metabolism].	8.57319e-16
NC_012814.1\|WP_004218482.1\|206745_209514_-\|YhgE/Pip-domain-containing-protein	gnl\|CDD\|224428	COG1511, COG1511, Predicted membrane protein [Function unknown].	3.59495e-89
NC_012814.1\|WP_004268977.1\|217559_219128_+\|C69-family-dipeptidase	gnl\|CDD\|335383	pfam03577, Peptidase_C69, Peptidase family C69.	0
NC_012814.1\|WP_004218486.1\|212775_214359_-\|ZinT/AdcA-family-metal-binding-protein	gnl\|CDD\|370371	pfam09223, ZinT, ZinT (YodA) periplasmic lipocalin-like zinc-recruitment. ZinT plays a critical role in recruiting periplasmic zinc to the bacterial zinc-uptake complex ZnuABC, consisting of families pfam01297,pfam00950, pfam00005, regulated by the transcription-regulator FUR, pfam01475. ZinT acts as a Zn2+-buffering protein that delivers Zn2+ to ZnuA (TroA), pfam01297. Members of this family of prokaryotic domains were first identified as part of the response of bacteria to a challenge with the toxic heavy metal cadmium. They are able to bind to cadmium, and ensure its subsequent elimination.	2.36038e-102
NC_012814.1\|WP_004218503.1\|230643_232794_+\|AarF/ABC1/UbiB-kinase-family-protein	gnl\|CDD\|223733	COG0661, AarF, Predicted unusual protein kinase [General function prediction only].	9.00342e-109
NC_012814.1\|WP_004218502.1\|230187_230535_+\|phasin-family-protein	gnl\|CDD\|226447	COG3937, COG3937, Uncharacterized conserved protein [Function unknown].	7.70598e-09
NC_012814.1\|WP_004218485.1\|211238_212726_+\|ATP-binding-cassette-domain-containing-protein	gnl\|CDD\|213193	cd03226, ABC_cobalt_CbiO_domain2, Second domain of the ATP-binding cassette component of cobalt transport system. Domain II of the ABC component of a cobalt transport family found in bacteria, archaea, and eukaryota. The transition metal cobalt is an essential component of many enzymes and must be transported into cells in appropriate amounts when needed. The CbiMNQO family ABC transport system is involved in cobalt transport in association with the cobalamin (vitamin B12) biosynthetic pathways. Most cobalt (Cbi) transport systems possess a separate CbiN component, the cobalt-binding periplasmic protein, and they are encoded by the conserved gene cluster cbiMNQO. Both the CbiM and CbiQ proteins are integral cytoplasmic membrane proteins, and the CbiO protein has the linker peptide and the Walker A and B motifs commonly found in the ATPase components of the ABC-type transport systems.	9.80258e-74
NC_012814.1\|WP_004218501.1\|229330_230080_+\|glutamine-amidotransferase	gnl\|CDD\|225974	COG3442, COG3442, Predicted glutamine amidotransferase [General function prediction only].	6.70842e-71
NC_012814.1\|WP_004218495.1\|221813_223109_+\|ammonium-transporter	gnl\|CDD\|223083	COG0004, AmtB, Ammonia permease [Inorganic ion transport and metabolism].	6.64221e-146
NC_012814.1\|WP_004218496.1\|223110_223449_+\|P-II-family-nitrogen-regulator	gnl\|CDD\|366157	pfam00543, P-II, Nitrogen regulatory protein P-II. P-II modulates the activity of glutamine synthetase.	1.87627e-50
NC_012814.1\|WP_004218481.1\|204550_206749_-\|YhgE/Pip-domain-containing-protein	gnl\|CDD\|224428	COG1511, COG1511, Predicted membrane protein [Function unknown].	3.31235e-80
NC_012814.1\|WP_004218497.1\|223759_225586_+\|nucleotidyltransferase-domain-containing-protein	gnl\|CDD\|235123	PRK03381, PRK03381, PII uridylyl-transferase; Provisional.	2.75736e-140
NC_012814.1\|WP_004218494.1\|220153_221554_+\|signal-recognition-particle-docking-protein-FtsY	gnl\|CDD\|236686	PRK10416, PRK10416, signal recognition particle-docking protein FtsY; Provisional.	1.18657e-157
NC_012814.1\|WP_004218498.1\|225946_226219_+\|helix-turn-helix-transcriptional-regulator	gnl\|CDD\|238045	cd00093, HTH_XRE, Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators.	9.90477e-14
NC_012814.1\|WP_004218500.1\|227753_229262_+\|Mur-ligase-family-protein	gnl\|CDD\|377986	pfam08353, DUF1727, Domain of unknown function (DUF1727). This domain of unknown function is found at the C-terminus of bacterial proteins which include UDP-N-acetylmuramyl tripeptide synthase and the related Mur ligase.	9.03252e-41

>NC_012814.1|WP_004268977.1|217559_219128_+|C69-family-dipeptidase
MSCTTLLVGKSASYDGSTIIARNDDSGSGTYDPKKFVAVRPEDQPRHYRSVISHMEIDLPGDPCLYSIVPNVRPNRGVLAEAGVNEHNVAMSATETIAVNSRVLAADPLVKLVPAHGEPGDADYREEVPGGFGEEDIITLVLPYVRTAREAVARIGELLATYGTYESNGIIASDVDEIWYVETIGGHHWIARRVPDDCYAAIPNQLGIDLLDIDDAMSECRNNMCSADLADFIEANHLDRAMPDPEFANHTAQHINPRTVFGTATPKDAIYNTPRAWYMQRHLNPSDDWDSPAAQYRPDSQDMPWAREPESKVTIEDVAFLMGSHFQGTPFDPYGTTGTAESRHRYRPIGVNRTGQMVCMQIRPYAPAAYRSIMWVSYGSGAFTTPAPFYANVTDTPAYLRDTDGENASTNSLYWTNRILAVMADAHYYDTDGEIEQYIEDVQAHGHRLVADTDASIRADADALASDSAHEGLKAVRLELETANKAMADWLQMRTQTLLNQVLYTTSNLMHNAFKMSDHWMS
>NC_012814.1|WP_004218491.1|216518_217229_-|hypothetical-protein
MAQHDNTNTEIIRPQGGSQTQAAADTAQIAHTQADAPTQPQGYAFDFAQQQGEQIPPSQGYAPQNGEQPFTTAANTAQPNMGGNGVPNNPQGGQMPMNGGAPGNRGTATLRGKPGGKTIGIIAAISLGCGLVAGIAGTAVTNAIYRSNEPSHSNMMMRGIGDRGFGEGDGDGESMPDFGSGNGSRNRRSYRADGQMPGMQDSDGANGESNGDARNRSQSNDSDSNADSGSSDSSKN
>NC_012814.1|WP_004218489.1|215571_216339_+|hypothetical-protein
MLVPMNDVNPYAAAAHIEVLPLTPTRQSIERALVEWMTQTGRPASDLSVSALCKKAFVARSTFYANYRHMGQVYESVENRLLRQLFECAVPMRVRADGTDETMRSFNAFVKVLHAHENEFRLVLVRQPSSRFVALWKQSLEYHVWHRLFETERGGAAAVDAVAEWGDGAAPGTSNGGSATSQEGLPAGTDADATNRNELPVRQGPATVNRALVFDMAATAFIAGVTFWLRTPQAVSLPEIRASVVKLVNNIDEIW
>NC_012814.1|WP_004218488.1|214554_215436_-|patatin-family-protein
MAVQQTTQPTRPTRREKVGVIDVGGGLRSAYSTGVLDYCLDNGIHFDYGLGVSAGAANITSYLAGQRGRPLRFYTKYCPRPEYMSLGNFLRDGSYLGLDYIYGTLMNEDGEDPLDYDALVAGGVPYRITVTDALSGMPKYLGPESMSRNHYDALKATACLPVLDKPYPLDGRPYFDGTISDPIPFRQAFADGCTKLVVILTRPRDFYRNPDKDIASSMMLAVRYPEAARALANRAHTYNVELNMCKRLEAQGKVRIIAPKSIDGVSTLTKDPDKIQNLYNRAYNDATALRNFL
>NC_012814.1|WP_004218486.1|212775_214359_-|ZinT/AdcA-family-metal-binding-protein
MTEQSTNQRSATHDEPRRRPITRTAIAFLAGLAVCGLAASTLSGCGNNAGENRTSAAAARQTTDSCDTTINVVASVNQWGSLAQQLGGSCVNVTSIINSTAADPHDHEATPADLTKLARADVVVLNGAGYDGWAQKAQLDEGRQRIVKASSLMGIADSQDDHDHEEGEGHHHHHGTVNPHLWFSPAAVLKMSEAITSAYVTKSGEASETAATARRHSNTWNAEYAEYTALVNRARAKNLQRRYVATESIIGHLLDYIGATDKTPDSYTNAMNNDAEPSASDLKNALDTVGSSNVDMLIVNPQEMGGFAKKLDAAARESGKTIISVTEQLPENHKTLLGWLTTITNQALADDPQHGWFLTQQVKDRTIADYAGQWRSVYPLLKNGKLRGVMEHKAATGDKTADEYTAYYDAGYKTDTETITIEGDRMAFTTNGRKVTATYRYDGHRILDYAKGNRGVRYLFTATGDVPQGAPKAVQFSDHGIAPGKAAHFHIFTGDSHDEVIKQMEHWPTYYPASMSDDEIVKEMLAH
>NC_012814.1|WP_004218485.1|211238_212726_+|ATP-binding-cassette-domain-containing-protein
MNGTRCALDGCSFRYASDESADGVERGVHAIDHVSLQARAGEVVMLVGRSGCGKTTVTRLLNGLAPEYFRGSLHGEARVGGLHAGVAAVEDYATEVGSVFQNPKTQYFHANSTDELAFPCENAGMEPSEIRRRIRERLRAFDVEHLHDRNIVDCSGGQQQQLAVVAATMLDPGVLVLDEPTSNLDAEAMERLRNMVKRLKRDGIAIVIAEHRLAWVADLADRYVVFDAGRVVGEYTAEQFHALPESQRRAWGLRALELSGPRGQVERIAQRAEPSGEKPVIATRGLKVGYERRRLFGRTKRGFVREVGDVNLFAGQIVGLIGRNGAGKSTFVKTVCGLVEPVAGEILVDGRAAKPGRLSALCAMVMQDVNYQLFASSVREEMLLEAMQHVRTAEDAQRVRERADGILRQLGLLDFAERHPMTLSGGQKQRLAIGVALMGEKRVVVLDEPTSGLDRHHMLQVGALMRDLADRGVCVLVVTHDDELAAEVCDRIVRF
>NC_012814.1|WP_004218484.1|210445_211186_+|energy-coupling-factor-transporter-transmembrane-protein-EcfT
MTEVVVPRETRVPIRATRGVLHFDPRVKLAMLVVANMMMFLHVGPYAGMMGVLLFSLPMLCGGKIALGMGMLACYAMCLGVDWLAAAVADAAPWLHVPGALAAGGAMMLPCLIAGMSAFATTPPGELVAALRRLHLPDAVVIPAIVLLRFFPTIARDYRMIRCSMRLRGINVGGWAMLCHPMRSLEYVLVPLLMNAANAAHDLTVSALTKGLGRRRATSSSAMLHMQAIDWAMLALCCLPLIPWQA
>NC_012814.1|WP_004218483.1|209807_210449_+|MptD-family-putative-ECF-transporter-S-component
MSDMERDARRREVRAAGGTRLTVADLINVGVFGAVYFALVGVAALASMAVFGVAGNILLPAIAAVLAGPVFMLMVARVRRFGAITLMGLMLGLFLFVSGHFATSLVTAIVFPLAADCIARFGAWRRPWALMLSYVVFSFGCTGPILPLWMMKDAYIASLERKGKDAAYIDALFGAVNGTTFVVAMVAIVIGALVGGLFGMRLMRRHFLKAAVA
>NC_012814.1|WP_004218482.1|206745_209514_-|YhgE/Pip-domain-containing-protein
MRNIWFILRRDLKRLIINPAAWVIIFGLTFIPALYAWFNIIGFWNPYGNTKGITVAVANEDAGADNAMMGKLELGDQIESTLKENHELGWTFLGKAKAMECVESGHCYAAIVIPRNFSENMAAVITGSGQRPTLEYYVNEKVNAVAPKMTDVGANTVDRQVNSAFVSTVSKAVTDTINTTNVQITQEGNATVAQTVAKLDATKANLSKSRTMIADLRKTLDGVDEKTTAAKQALAGVDSAATSASQGLTSASGLLTKTQGGITSFSNDLSTELDQGGNLFLQASGKASTSATRVANGVLTASGATGSALNELTSVNKTNAQILADLKALPDNPLSEQINEIVTDLSAENEKVAQTLQTLTTLNDSTTAAANSTLGTVDQFSATSTTTVDALSGARNTINSSAIPQLNSGLATLSGTAGTLSGFLTGTQSLTGQTNLILDQLTQICQSTSSSLNSTDDLLGKFITRIDTVTTDLKTLENTNVLSDLLGSKNGTLDASRIASFMLSPTVLDTHTLYPIDTYGSGMAPLFTSLALWVGVFMLMVLFKLEVDNEGLEGRHVTTNQTYMARYLLLAIVAGLQGIVCAVGDLIIRVQCANRFVFILTAWLTSLAYLAIAYALSATFMHVGKALVVALVMLQIPGASGLYPIEMMPDFYRALYPFFPFTYSINAFRETIAGFYDGDWLTKMLMLALFTAIAFFVGLVVRPWLGNFNHLFAREVHEGDMIVGERVYMPANRFDLAQALHVLADHGEYRRRIERRAKRFATLYPRLMRGALVAGFAVPIVLFIVFSFVGASDGSKLVALATWIAWILIIIIFLMTVESIRESLRRQTELGSLSEDSLRDMIMAQGVFGNNRHHITVPADELRPDAASNSRERAEKRREERDLNHREDTLDLNLNELRKPERQRKHRGSTSRRNHHDGRHSA
>NC_012814.1|WP_004218481.1|204550_206749_-|YhgE/Pip-domain-containing-protein
MSMLAKIFADDVRHLTSNIVSIIITIGLIVIPGLFTWFNVAACWDPFANTKNLQFAIANDDEGYKGDLLPMRINIGEQVVDTLRANSQLDWTFTKSSAEAIDGTKSGKYYAAVVIPKNFSKNMMTFFTDDAYHATLDYYNNEKLNALAPKVTGQGADTIAATINQTFSKTLTDTALNLASSMLDMLDKPEYQQRLKSFNGNIADLAGMLNDSAAVLRTYSSLTDSAKTLLASSNKLIADARASAKTGVDDLSAAKTGVSDLSGALGTSVNALGTAIDTSKTSLGSLNDRVDELFSAVDKQAGDTSAAINNLAGNVRTEATAYATTRGRLQELLDKSDNLGPVAKSAVQAFINRIGAVADDLNQTADRLTTAANDVDSKVGSSKETRQEIKDLAGKAQSSVSSISKDFDETIKPDLTAMTNAFSDAANSLNGTVSTLDSSLDSLSGTASDANKQLDSVHELIDNAATQLTDAAKELTNFNTQFAKALDTGNMGTIKKLLSGNTATLSTALSTPVELKRVALFPVDTFGAALTPFYTFLPLWVGALLLVVTLKIGISRKRQRELGNPKPWQIFLGHYGVFVSIALLQSTFSCAGTLLFLRVQVVHPWLFMLVGWFSSIVYSFFTYTLVSTFANVGKAIGVLFLVMQISGSNAAYPLSILPHFISDISPWLPVSYSVTAMRGAIAGIYENDYWIAMGKLALFLVPLLFIGLVLRHALLGFNHWYEARVERTKLLG
>NC_012814.1|WP_004218494.1|220153_221554_+|signal-recognition-particle-docking-protein-FtsY
MDTNTIYAIVIIAVIAVALIIGSWLIGRSRRNAINKSTEHAKAAADARLAAERAQAEQEEREAHEQAKEPAESGARQSSGGKPAEPTNEEKIEAEEPAISRAELEAQERERLSQTPPKLAAAEEVPGEESAQAESVVEDLAVVDEVPTPPAEQIEKPAGKKSRLQRLRERLSKSSNPFGKALFNILAKDQLSEADWEDVEDTLLLADVGAEASEELVDKLRTDARVTGESDPRQLRDALRSELLALVGPDMDRTLEAEKPDAKKPSVIIMVGVNGTGKTTTAGKLARLFVSEDKTVLLGAADTFRAAAADQLETWGAKVDVPVVRSDREGADPASVAFEASAKAKELGTDVLIIDTAGRLQNKANLMDELGKIRRVAEKNLPVDEVLLVLDATTGQNGMAQAKVFAEAIGITGVVLTKLDGSAKGGIVISVQKELGVPVKLVGVGEGPDDLAPFDPESFVDGILGE
>NC_012814.1|WP_004218495.1|221813_223109_+|ammonium-transporter
MSQLDSGNAAWILTSACLVFLMTPGVALFYGGMVRAKAVLNMLIMEAAALSVTMIIWGLWGWSIAYAGNSIGGVFGDPATGFLLRDTMVAQDGVFTSASLNSNNYPASVDVAFQAAFAMITVALICGAIAERVKYSTWMIFVALWITFDYAPMAHMVWNGGLLSADGAISQALGAAAHDFAGGTVVHINAAVAALIIVLIIGKRKGFGVEPMRPHNVPFVMLGAFLLWFGWFGFNAGSAFAANGVAGYAWVSTSLAAAAAMLTWGFTEKIRTGHYTAMGAASGIVAGLVAITPAADVVSPIWAIVLGAIAGVVTCLACSLKFKLGYDDSLDVVGVHGVGGLVGTVLLGFFMEGTGLFYSGKWNQLGVQLIIAIIAIAFSAVITTIIAFALEKTIGWRVTQAQEVAGIDLADQGERAYDFAGTASSVIREMK
>NC_012814.1|WP_004218496.1|223110_223449_+|P-II-family-nitrogen-regulator
MKLITAIIQPHKLDDVKEALASAGVHGLTVSEANGYGRQRGHTEIYRGAEYTVDLIPKVRVEVLSDDADAETLVDVIVKSAGSGTIGDGKVWVAPLDMVVRVRTGETGSAAI
>NC_012814.1|WP_004218497.1|223759_225586_+|nucleotidyltransferase-domain-containing-protein
MAMSTLKQQFLELSEPDADGVYRNGSAKRMARTNLAMRELEALWNEAVHSVPFQIPDSGIGLAAVGSLARGQIGPASDLDLVLITADHVALSTTQLNEFANKLWYPIWDSGLDLDHSVRTVSRCESVTDHDLPAAMGWLNVNPIAGDRHLIETTATAILERWRKAARKRLPELLESANVRNERFDRMSYVNQPDIKESRGGLRDTVLLSALAASWLADRPHGRYDDAVERLLDVRDAIHLITRKDADRLLTQYQAEVAAMLGLTDPTLPEGEREAKSIDDLQTLLASLSRTIAFALDSTASRAQRTLVHDKPRFSFFQILSPRAGGKREAPKFEMLAPGVAKHEQEIVLAPQADPLADPALPLRVAAAAGREGLPINTSTLVNLKRAPIHDKAWSDEMRRLFVELLASGERLPQVWEELDFVGIPGRLMPEWDAIRNRPSVSAAHRYTIDRHMLAVTAQLGRERPVNGGAFDDVHYTALLLAGILHDIGKRPGVADHAAEGARHAAVIVRRMGFDDQMVDWVRLLVREHLTLSDFASSRNPNDPEVGAELASLVDGDPQLLDMLFALTKADMSSLGATAGETISNTVGWSKWRARLVTQMAALARASM
>NC_012814.1|WP_004218498.1|225946_226219_+|helix-turn-helix-transcriptional-regulator
MRSFNSMLDEQMDDPEFATVFEAEIERLNAAVAVSRAREEARLTQEQLAERSGVSRVTINRIERGKLNPSMKTLSRLARAMGKQVRVSIS
>NC_012814.1|WP_004218499.1|226277_227657_+|replicative-DNA-helicase
MADGFHNNTRTDTSANAAGLFDRVPPHDDNAEMATLGGMLMSKDAIGEVSQIVSVDDFYEPKHQTIYEAIIGKFSASEPADAVTVANRLSDSGDLDKVGGIDYLHSLIASVPTAANASYYAEIVHQRALLRRVIASGTKIAQLGYDAEGSQAQDVINMAQAEVYEMSTGRVRQDYAPVQAAVHDALDQIDSIQKGELQAGVPTGFQEIDEVTKGLQPGQMVVVAGRPAMGKSTLGVDFARSAAIHHHDTTILFSLEMSKVELAQRIISAETGVPLAALRNADDIDPNRWNTLNNFYARLQDAPLFIDDSPNMSLMEIRAKCRRLKQTNDLKLVVIDYLQLMTSGKAVESRQQEVSEFSRALKLLAKELEVPVVALSQLNRGPEMRNDKKPQLSDLRESGSIEQDADVVFLVHRPDFYDEEDRPGEADIIMAKHRNGPTRTFGLVFQGQYSRFSDMNREV
>NC_012814.1|WP_004218500.1|227753_229262_+|Mur-ligase-family-protein
MADSGTSNANPVRTHAPWYGFATPFVGKSVRWASRLLHHGGSAFPGKVVERFDPTFLSRTLSTLPLGVVLVSGTNGKTTTTRMVATMLESLGLKVFTNPTGSNFTRGVVSSILTEVPLNGRLDADIAVLELDEAYAVHFVEQVQPRYALLLNVMRDQLDRFGEIDNTARLLGHVAAATRGTVVLNREDPRIARLRDVVKDGVRTRYFGLAEGLRHYFPADDDMTTTFQVQSADSAQAPEAADAQIVDVAHDVGTAHELHADVMLTKVGDHHAQMVIDGREYESDVKLEGVYNLFNAAAALAVVRAVQADLRKPNAVGYAAAQLGRADSARARAFTARAHTFADADTDALFAALADVTPAFGRGEVIDVNGSPVELLLVKNPMGFRLALASFPPESADTMIAINDQYADGRDMSWLWDVDFTSLRPTGVAMVSGVRAWDMALRLEYDQVPVARVEPDLNAAVREFVNANPGTPKHIYCTYTAMLAIRAELATVADVADAGVGK
>NC_012814.1|WP_004218501.1|229330_230080_+|glutamine-amidotransferase
MSKAIDVVSLYPKDMNIYGDSGNVLAVERRLALYGYEPHVHAVNQNDPWPEHADIILGGGGQDTGQKKIIEDLFRRADRLRDLAEHGVPMLMICGLYQLFGEYFETIDGTKLEGISIIRAYTVGRDVRMIGNLVEHSAQFGDVLGYENHSGQTFLREGVQPLGTVDGDGTGNNGEDHTEGARVHNVIGTYMHGSLLPKNPKITDFMIRTAVERRYGAFDPEQTDAQRAELARIDEYAAHAREAAATRPR
>NC_012814.1|WP_004218502.1|230187_230535_+|phasin-family-protein
MTDETKNETENKTNSAMPDFGEGLRKVFLAGVGAIAATAEKGQELVNDLVKRGELTVEQGKKLNSELAHKAGEKSDSLKEKLADASNTVRNAAAGLSDQAEQTIKKATEKKSDEQ
>NC_012814.1|WP_004218503.1|230643_232794_+|AarF/ABC1/UbiB-kinase-family-protein
MSDKNSDKSKRETEAHELRRDVRREEAGQRRQQRKDACEARHLEHEEKRETSELIDLSNRLENQEAHSDGPAFDNPTDDALRATVETAESEKILHLGDEVDEQGATIEHNLQREEAEQSGGEASETAAQPETPAPQSAQSERPADAHTHDIPASIARRQQPQVEETIGLFGMHKRNFSSEYHLTRMSKAKRLKQIGKIALEYDALHGLTPVKMRLMFEALGPTFVKVGQILSMRSEILPESFCAELSKLRADADPMPYAIVLGTLENEYQRPIDEIFEHIDTTPLGSASLAQVHRATLKTGEDVAVKVQRPGVRETMAQDVSIMRSLAKGATKIMHSSQVVDFRGVVEELWETFDEETNFLNEARNLAEFKRFCSHYAYMDCPTPFTDLCTEHVLVMQYIDGIPISHTRELIDDGYSLNEIGTKLVDNYAAQILDAGFFHADPHPGNIEIRGGKIILLDLGMTGRLDARTRVALKQMLFAVAKQNSADLADALLRFAGTDVERADYPSLLGDLDGIVEEFGTVDLADLDLAAFITSLTQMARRHGIEIPSSVTTVGRALVTLEGLLDEFIPNVNMIEIISQHIESSKTPVEMVKSEVKRLGIESEQALHSGLKGIVDAQTALHMLTRGELKMNLELVGSEEPLSQMSDMVNRLTMALIVVGLFIGSSIVYFAGMKPIIFGIPVVGFLGYVAAFVLSVWIVIDILIKRHAAKHKARK

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Crispr_ID: NC_012814_3

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_012814_3

1319465-1319650

Orphan

Consensus_repeat	Method
TTGCGTAAAAAGAGACAGA	PILER-CR

2 spacers

The CRISPR arrays of NC_012814_3

>merge|NC_012814|3|1319465-1319650|PILER-CR
TTGCGTAAAAGGAGACAGATTAAGCAAGAATCTGTCCCTTTTACGCATGATTATCTCGTGTGTGAACACCTTGTGTGCAAGTGCCCCTCAGCGTAATCAGCGTAAAAAGAGACAGTTCCGGTAAGGAAATTGTCTCCGATTACGCAACTAACCGTATGCACTCCCGTTTGCGTAAAAAGAGACAGA

>NC_012814|3|1|1319465-1319650|PILER-CR
TTGCGTAAAAGGAGACAGA	TTAAGCAAGAATCTGTCCCTTTTACGCATGATTATCTCGTGTGTGAACACCTTGTGTGCAAGTGCCCCTCAGCGTAAT
CAGCGTAAAAAGAGACAGT	TCCGGTAAGGAAATTGTCTCCGATTACGCAACTAACCGTATGCACTCCCGT
TTGCGTAAAAAGAGACAGA

Protein	Signature genes	Signature genes Name	Protein_function
NC_012814.1\|WP_004218710.1\|1330861_1331113_+\|hypothetical-protein	unknown	unknown	unknown
NC_012814.1\|WP_004218716.1\|1327068_1327875_+\|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|224059
NC_012814.1\|WP_004218727.1\|1315923_1316694_-\|DUF3159-domain-containing-protein	unknown	unknown	gnl\|CDD\|371490
NC_012814.1\|WP_004218724.1\|1318787_1319462_+\|membrane-protein	unknown	unknown	unknown
NC_012814.1\|WP_004218722.1\|1321781_1322738_-\|ABC-transporter-permease	unknown	unknown	gnl\|CDD\|224094
NC_012814.1\|WP_004218733.1\|1307041_1307683_-\|sugar-O-acetyltransferase	unknown	unknown	gnl\|CDD\|100047
NC_012814.1\|WP_089194267.1\|1319721_1321710_-\|ABC-transporter-ATP-binding-protein	unknown	unknown	gnl\|CDD\|224048
NC_012814.1\|WP_004218731.1\|1308190_1310890_-\|aconitate-hydratase-AcnA	unknown	unknown	gnl\|CDD\|236445
NC_012814.1\|WP_004218730.1\|1310957_1313528_-\|HAD-IC-family-P-type-ATPase	unknown	unknown	gnl\|CDD\|319795
NC_012814.1\|WP_004269170.1\|1317753_1318614_-\|endonuclease/exonuclease/phosphatase-family-protein	unknown	unknown	gnl\|CDD\|197336
NC_012814.1\|WP_004218721.1\|1322751_1323678_-\|ABC-transporter-permease	unknown	unknown	gnl\|CDD\|223674
NC_012814.1\|WP_004218708.1\|1332231_1333347_-\|chorismate-mutase	unknown	unknown	gnl\|CDD\|270350
NC_012814.1\|WP_004218726.1\|1316762_1317620_-\|DUF3710-domain-containing-protein	unknown	unknown	gnl\|CDD\|378867
NC_012814.1\|WP_004218718.1\|1325894_1326830_-\|tyrosine-recombinase-XerC	unknown	unknown	gnl\|CDD\|234698
NC_012814.1\|WP_004218729.1\|1313576_1314164_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|380532
NC_012814.1\|WP_004218728.1\|1314499_1315810_-\|class-I-SAM-dependent-RNA-methyltransferase	unknown	unknown	gnl\|CDD\|225174
NC_012814.1\|WP_004218709.1\|1331128_1332223_-\|prephenate-dehydrogenase/arogenate-dehydrogenase-family-protein	unknown	unknown	gnl\|CDD\|235824
NC_012814.1\|WP_012619816.1\|1327882_1330717_+\|FtsX-like-permease-family-protein	unknown	unknown	gnl\|CDD\|226957
NC_012814.1\|WP_004218732.1\|1307855_1308107_+\|hypothetical-protein	unknown	unknown	unknown
NC_012814.1\|WP_004218720.1\|1323977_1325618_-\|ABC-transporter-substrate-binding-protein	unknown	unknown	gnl\|CDD\|173853

Protein	Function_ID	Function_description	E-value
NC_012814.1\|WP_004218716.1\|1327068_1327875_+\|ABC-transporter-ATP-binding-protein	gnl\|CDD\|224059	COG1136, SalX, ABC-type antimicrobial peptide transport system, ATPase component [Defense mechanisms].	7.2024e-112
NC_012814.1\|WP_004218727.1\|1315923_1316694_-\|DUF3159-domain-containing-protein	gnl\|CDD\|371490	pfam11361, DUF3159, Protein of unknown function (DUF3159). Some members in this family of proteins with unknown function are annotated as membrane proteins however this cannot be confirmed. Currently this family of proteins has no known function.	7.39971e-73
NC_012814.1\|WP_004218733.1\|1307041_1307683_-\|sugar-O-acetyltransferase	gnl\|CDD\|100047	cd03357, LbH_MAT_GAT, Maltose O-acetyltransferase (MAT) and Galactoside O-acetyltransferase (GAT): MAT and GAT catalyze the CoA-dependent acetylation of the 6-hydroxyl group of their respective sugar substrates. MAT acetylates maltose and glucose exclusively at the C6 position of the nonreducing end glucosyl moiety. GAT specifically acetylates galactopyranosides. Furthermore, MAT shows higher affinity toward artificial substrates containing an alkyl or hydrophobic chain as well as a glucosyl unit. Active MAT and GAT are homotrimers, with each subunit consisting of an N-terminal alpha-helical region and a C-terminal left-handed parallel alpha-helix (LbH) subdomain with 6 turns, each containing three imperfect tandem repeats of a hexapeptide repeat motif (X-[STAV]-X-[LIV]-[GAED]-X).	2.64242e-97
NC_012814.1\|WP_089194267.1\|1319721_1321710_-\|ABC-transporter-ATP-binding-protein	gnl\|CDD\|224048	COG1123, COG1123, ATPase components of various ABC-type transport systems, contain duplicated ATPase [General function prediction only].	0
NC_012814.1\|WP_004218731.1\|1308190_1310890_-\|aconitate-hydratase-AcnA	gnl\|CDD\|236445	PRK09277, PRK09277, aconitate hydratase AcnA.	0
NC_012814.1\|WP_004218730.1\|1310957_1313528_-\|HAD-IC-family-P-type-ATPase	gnl\|CDD\|319795	cd02609, P-type_ATPase, uncharacterized subfamily of P-type ATPase transporter, similar to uncharacterized Streptococcus pneumoniae exported protein 7, Exp7. This subfamily contains P-type ATPase transporters of unknown function, similar to Streptococcus pneumoniae Exp7. The P-type ATPases, are a large family of integral membrane transporters that are of critical importance in all kingdoms of life. They generate and maintain (electro-) chemical gradients across cellular membranes, by translocating cations, heavy metals and lipids. They are distinguished from other main classes of transport ATPases (F- , V- , and ABC- type) by the formation of a phosphorylated (P-) intermediate state in the catalytic cycle. A general characteristic of P-type ATPases is a bundle of transmembrane helices which make up the transport path, and three domains on the cytoplasmic side of the membrane. Members include pumps that transport various light metal ions, such as H(+), Na(+), K(+), Ca(2+), and Mg(2+), pumps that transport indispensable trace elements, such as Zn(2+) and Cu(2+), pumps that remove toxic heavy metal ions, such as Cd(2+), and pumps such as aminophospholipid translocases which transport phosphatidylserine and phosphatidylethanolamine.	0
NC_012814.1\|WP_004218729.1\|1313576_1314164_-\|hypothetical-protein	gnl\|CDD\|380532	cd06309, PBP1_galactofuranose_YtfQ-like, periplasmic binding domain of ABC-type galactofuranose YtfQ-like transport systems. Periplasmic binding domain of ABC-type YtfQ-like transport systems. The YtfQ protein from Escherichia coli is up-regulated under glucose-limited conditions and shares homology with a family of pentose/hexose sugar-binding proteins of the type 1 periplasmic binding protein superfamily. Members of this group are predicted to be involved in the transport of sugar-containing molecules across cellular and organellar membranes; however their ligand specificity is not determined experimentally.	0.000557278
NC_012814.1\|WP_004218721.1\|1322751_1323678_-\|ABC-transporter-permease	gnl\|CDD\|223674	COG0601, DppB, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism].	2.47608e-107
NC_012814.1\|WP_004218708.1\|1332231_1333347_-\|chorismate-mutase	gnl\|CDD\|270350	cd13632, PBP2_Aa-PDT_like, Catalytic domain of prephenate dehydratase from Arthrobacter aurescens and similar proteins, subgroup 3; the type 2 periplasmic binding protein fold. Prephenate dehydratase (PDT, EC:4.2.1.51) converts prephenate to phenylpyruvate through dehydration and decarboxylation reactions. PDT plays a key role in the biosynthesis of L-Phe in organisms that utilize the shikimate pathway. PDT is allosterically regulated by L-Phe and other amino acids. The catalytic PDT domain consists of two similar subdomains with a cleft in between, which hosts the highly conserved active site. In gram-postive bacteria and archaea, PDT is a monofunctional enzyme, consisting of a catalytic domain (PDT domain) and a regulatory domain (ACT) (aspartokinase, chorismate mustase domain). In gram-negative bacteria, PDT exists as fusion protein with chorismate mutase (CM), forming a bifunctional enzyme, P-protein (PheA). The CM in the P-protein catalyzes the pericycle isomerization of chorismate to prephenate that serves as a substrate for PDT. The CM and PDT are essentail enzymes for the biosynthesis of aromatic amino acids in microorganisms but are not found in humans. Thus, both CM and PDT can potentially serve as drug targets against microbial pathogens. The PDT domain has the same structural fold as the type 2 periplasmic binding proteins (PBP2), many of which are involved in chemotaxis and uptake of nutrients and other small molecules from the extracellular space as a primary receptor. The PBP2 proteins are typically comprised of two globular subdomains connected by a flexible hinge and bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap.	3.50315e-48
NC_012814.1\|WP_004218726.1\|1316762_1317620_-\|DUF3710-domain-containing-protein	gnl\|CDD\|378867	pfam12502, DUF3710, Protein of unknown function (DUF3710). This family of proteins is found in bacteria. Proteins in this family are typically between 237 and 284 amino acids in length. There are two conserved sequence motifs: DLG and DGPRW.	1.21457e-62
NC_012814.1\|WP_004218718.1\|1325894_1326830_-\|tyrosine-recombinase-XerC	gnl\|CDD\|234698	PRK00236, xerC, site-specific tyrosine recombinase XerC; Reviewed.	1.25243e-141
NC_012814.1\|WP_004218728.1\|1314499_1315810_-\|class-I-SAM-dependent-RNA-methyltransferase	gnl\|CDD\|225174	COG2265, TrmA, SAM-dependent methyltransferases related to tRNA (uracil-5-)-methyltransferase [Translation, ribosomal structure and biogenesis].	3.30445e-81
NC_012814.1\|WP_004218722.1\|1321781_1322738_-\|ABC-transporter-permease	gnl\|CDD\|224094	COG1173, DppC, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components [Amino acid transport and metabolism / Inorganic ion transport and metabolism].	1.74143e-86
NC_012814.1\|WP_004218709.1\|1331128_1332223_-\|prephenate-dehydrogenase/arogenate-dehydrogenase-family-protein	gnl\|CDD\|235824	PRK06545, PRK06545, prephenate dehydrogenase; Validated.	1.78829e-64
NC_012814.1\|WP_012619816.1\|1327882_1330717_+\|FtsX-like-permease-family-protein	gnl\|CDD\|226957	COG4591, LolE, ABC-type transport system, involved in lipoprotein release, permease component [Cell envelope biogenesis, outer membrane].	2.14759e-23
NC_012814.1\|WP_004269170.1\|1317753_1318614_-\|endonuclease/exonuclease/phosphatase-family-protein	gnl\|CDD\|197336	cd10281, Nape_like_AP-endo, Neisseria meningitides Nape-like subfamily of the ExoIII family purinic/apyrimidinic (AP) endonucleases. This subfamily includes Neisseria meningitides Nape and related proteins. These are Escherichia coli exonuclease III (ExoIII)-like AP endonucleases and belong to the large EEP (exonuclease/endonuclease/phosphatase) superfamily that contains functionally diverse enzymes that share a common catalytic mechanism of cleaving phosphodiester bonds. AP endonucleases participate in the DNA base excision repair (BER) pathway. AP sites are one of the most common lesions in cellular DNA. During BER the damaged DNA is first recognized by DNA glycosylase. AP endonucleases then catalyze the hydrolytic cleavage of the phosphodiester bond 5' to the AP site, and this is followed by the coordinated actions of DNA polymerase, deoxyribose phosphatase, and DNA ligase. If left unrepaired, AP sites block DNA replication, and have both mutagenic and cytotoxic effects. AP endonucleases can carry out a variety of excision and incision reactions on DNA, including 3'-5' exonuclease, 3'-deoxyribose phosphodiesterase, 3'-phosphatase, and occasionally, nonspecific DNase activities. Different AP endonuclease enzymes catalyze the different reactions with different efficiences. Many organisms have two AP endonucleases, usually one is the dominant AP endonuclease, the other has weak AP endonuclease activity; for example, Neisseria meningitides Nape and NExo. Nape, found in this subfamily, is the dominant AP endonuclease. It exhibits strong AP endonuclease activity, and also exhibits 3'-5'exonuclease and 3'-deoxyribose phosphodiesterase activities.	8.13408e-110
NC_012814.1\|WP_004218720.1\|1323977_1325618_-\|ABC-transporter-substrate-binding-protein	gnl\|CDD\|173853	cd00995, PBP2_NikA_DppA_OppA_like, The substrate-binding domain of an ABC-type nickel/oligopeptide-like import system contains the type 2 periplasmic binding fold. This family represents the periplasmic substrate-binding domain of nickel/dipeptide/oligopeptide transport systems, which function in the import of nickel and peptides, and other closely related proteins. The oligopeptide-binding protein OppA is a periplasmic component of an ATP-binding cassette (ABC) transport system OppABCDEF consisting of five subunits: two homologous integral membrane proteins OppB and OppF that form the translocation pore; two homologous nucleotide-binding domains OppD and OppF that drive the transport process through binding and hydrolysis of ATP; and the substrate-binding protein or receptor OppA that determines the substrate specificity of the transport system. The dipeptide (DppA) and oligopeptide (OppA) binding proteins differ in several ways. The DppA binds dipeptides and some tripeptides and is involved in chemotaxis toward dipeptides, whereas the OppA binds peptides of a wide range of lengths (2-35 amino acid residues) and plays a role in recycling of cell wall peptides, which precludes any involvement in chemotaxis. Similar to the ABC-type dipeptide and oligopeptide import systems, nickel transporter is comprised of five subunits NikABCDE: the two pore-forming integral inner membrane proteins NikB and NikC; the two inner membrane-associated proteins with ATPase activity NikD and NikE; and the periplasmic nickel binding NikA, which is the initial nickel receptor that controls the chemotactic response away from nickel. Most of other periplasmic binding proteins are comprised of only two globular subdomains corresponding to domains I and III of the dipeptide/oligopeptide binding proteins. The structural topology of these domains is most similar to that of the type 2 periplasmic binding proteins (PBP2), which are responsible for the uptake of a variety of substrates such as phosphate, sulfate, polysaccharides, lysine/arginine/ornithine, and histidine. The PBP2 bind their ligand in the cleft between these domains in a manner resembling a Venus flytrap. After binding their specific ligand with high affinity, they can interact with a cognate membrane transport complex comprised of two integral membrane domains and two cytoplasmically located ATPase domains. This interaction triggers the ligand translocation across the cytoplasmic membrane energized by ATP hydrolysis. Besides transport proteins, the PBP2 superfamily includes the ligand binding domains of ionotropic glutamate receptors, LysR-type transcriptional regulators, and unorthodox sensor proteins involved in signal transduction.	5.09772e-137

>NC_012814.1|WP_004218724.1|1318787_1319462_+|membrane-protein
MTKPTDSPAAKLPMPRGFKLFIALAVLMVVGAAISLFDKSEFYADVFIEISVFCVFLAGFFTNTRTLQFAYLVGANIYVIVCLGAFSTVFFTKMNQGVGVLLIIQIIFSCLNLVPIIIYHLTDREFFYTYQRQLIYPTLFFVFVLLGHLPGGDVLTSEVSHEIFSLIIFAQAFEIMDAIHKVGKAHHMAAYAINTQPLGTKLVPDTDDADDSEGSLDEPEDVEE
>NC_012814.1|WP_004269170.1|1317753_1318614_-|endonuclease/exonuclease/phosphatase-family-protein
MALTITTSNLNGIRAAKRKGFDHWAKAHTPNVWCMQETRAPQEIIADIYGELAADYVHAGKIASPEELHTLVDVCRIKGRAGVGMISDMPVLETRVGLPGLEEDVDSGRWIEADVRTEQGYVITVVCVYVHAGGLVDDPKEAQKYRFLDTMTERMQQLQDEAASGGRQAVVCGDFNIAHNPIDLKNPKSNENNNGYFPRERAYMDKWIDQMDYVDVMRDLAGDIQGPYTWWSQRGRAFDNDSGWRLDYQFATPELAQQARGFVVDRASSYDSRWSDHAPLTISYDV
>NC_012814.1|WP_004218726.1|1316762_1317620_-|DUF3710-domain-containing-protein
MGLFGFGRKKKKQQDDERLAEAVDSRTEDVAVEDSEDDEQTEVLEGARTEVGVDYEGRGETVGPWDVDDANAPDYDEYLSLGAYYLPFVQGIQLRIKANNATHEIVGATMTIGNSSLEVEAFAAPKTMGLWDDVREDLLASNPEAEAVDGIFGTEVKLPVKLPNGKTAHTRIVGVDGPRWMLRGIFSGKAASDPDGTETKILNDAFAQIVVERGDEPLSPRDPIPMARPLTPNERRALAAQEEDGDLAGDDHSKIPGRPDGPLSTDQQVEQQTTLRRGPMFSEVR
>NC_012814.1|WP_004218727.1|1315923_1316694_-|DUF3159-domain-containing-protein
MSNQNERHASNTRPARARSGMAALANAGENDEFSVIAAIGGVRGVVESMLPGLLFVVLFICTSDLRMTVIASAALAVVQVVVRLIQRQSVMGALGGLVAVGICLFWAWKSGEARNYYMYGFITNAAYIVLLLVSMAVRVPGLGFLVEFIRSLPTEHFKAWLSGWRSDRALYKAYARITWLWIGLFALRLIVQVPLYMTNQVGWLGTTRLVMGIPFWALAIWISYLIVADPLHRHRMLEKERESTSTEGGDAHPTAQ
>NC_012814.1|WP_004218728.1|1314499_1315810_-|class-I-SAM-dependent-RNA-methyltransferase
MEATVDIERYADQGRCVAHIDGRVVFVRFALPGERVRIELDEPTNRNDRFWTGEVVEVLEPSPDRVEPLWPLAAPLAMGGGAGGADLIHVSLEGQERWKEATLKDVMKRLGHVDLDDVPVYAMPGDEQAHGLHWRTRIEMVTDDEGRPSMRRRGTHVRVPIDTMPLATRAVLEVAEMNGVWDGNLPENAQIRIAVPEPRVDAEQIADPEALRKAIGRNYAIMVDGKVRHGSRALKETIMVDGKPFEYTVDAGGFWQMHREAPMVLPQYVIDQIRETPGDRAPRNGRNLVIWDLYSGSGLFTLPLATLLDDRAKLVSIEGAKDAVANARRNLRNAGIHTVQALCGDVLHTLDKDIDPQRAHPDIVVLDPPRAGAKAKVCHKIANSGAPIVVYIACDPASLARDTATLTEHGYRIHSIAAFDIYPQTHHVETVAVFVK
>NC_012814.1|WP_004218729.1|1313576_1314164_-|hypothetical-protein
MARRTKRLAAIACAVAALALMAGCTPKGAAVGDTQNNETYEHNHNENTGARLDVAVIGSPHGGADELVMRSLATKEFKASYTGVQQYSADPQRAADFARKAVSDAVSRHPKVIVISGLTFHDDESQWNTALANARNAGIPVVLLNPADVPGDTKLFAATFVVNDRMMDAQPMGEALRSVIFDHPHEREIVVSTRS
>NC_012814.1|WP_004218730.1|1310957_1313528_-|HAD-IC-family-P-type-ATPase
MSDSANAQQSVSMTGAQGGDDHAHMPDVTEKGLTAAEVRDRVERGQTNEVKSSTSRSLADIVRANVFTLFNGIIFTAMVMVLITGSWKDAVFGLVILINTGIGIVTELRAKRTLDKLSILIASDYLVRRDGKDVDVPHNGIVLGDCLWIRSGEQIPCDAEILHTWGLELDESMITGESRTVRKQEGETVYSGSTAVSGMALVKVTAVGAHSYAATLTAQAKVYKKNVSDLNKGINTILKFMTFLVVPLCMLLIVTQMRTVGGWHNAIATGEWRQAVVSSVAGVVGMVPEGLVLLTSLNFALAAIRLARKNTLVQDLDSVETLARVDALNLDKTGTITDGGIVYDDFIALPGCRNKQHAMQALYDLANEESPNGTGRAVLEGLGKQGFSGSAGLVRVPFSSARKWSAVAFHGLPDEGQNGVWYMGAPEVLLSGFDGEYQQILAQVNEYANNGNRVLLIAHVPGGDVPADFETNPQLERTAVPVAIVLCSEHIRSDAEPTLRWFREQGVRCRVISGDNPVTVGAIAAKVQLTGERKPVAMDARELPKNVDELARVLEGVDVLGRVLPEQKKAIVQALHTQDHVVAMTGDGVNDALAIKEADLGIAMGNAAPATKAVAEVVLVDSKFSHLPDVVARGRQVMANMERVASLFVTKTAYSALISLGVVLMGIPFPYLPRHISYIGALTIGAPAFFLALAPNTRRYIPGFLRRVVAFSVPCGIATGLSVLLSAWFIPRFMHWNVFTSEQQLFWLRSMCATVLFLMGIYVLSRVSKPLNSWRGWLVLAFAAAGVIGACIPFIARFFAFGLPAGRAVWILLLQMAVATVLFVISIWVFSRFLPKWMREAGRETGINGASHNTNG
>NC_012814.1|WP_004218731.1|1308190_1310890_-|aconitate-hydratase-AcnA
MSLRDEQLDVLKVGDKSYDYYRIADLEGVDHLPYSLKVLVENLVRNIDGANITDEQVRELLAWDPAADPSHEIQFIPSRVVMQDFTGVPCVVDLATMRDAVKSLGGDPEVINPQVQSDMIIDHSVQIDAYGVENAVEINMDIEYQRNGERYRFLRWGQQAFENFRVVPPGTGIIHQVNIEYLAQVVMRKELSKGTTLAYLDSCVGTDSHTTTVNGLGVLGWGVGGIEAEAAMLGQPISMLVPRVVGFKLTGSIPEGVTATDVVLTITDLLRRHGVVGKFVEFYGEGIASVPLANRATIGNMSPEFGSTCGIFPIDEVTLDYLRLTGRSEEQVALVEAYAKANKLWHDVNDPNFVEPSYSEYLELDLSTVVPSIAGPKRPQDRIELSHAKTTFEQTLPGYITEKTNGNPVPVSTDFRGDFELTNGDVAIASITSCTNTSNPSVMIAAGLIARNAVAKGLKPKPWVKTSLAPGSQVVADYLKQAGLQDDLDRLGYELVGFGCATCIGNSGPLLPEISEAINANDLTVTAVLSGNRNFEGRISPDVKMNYLASPPLVIAYALAGTMDFDFEHEALGKDPEGNDVYLKDIWPTNAEVEQVVSGNVSREMFLNDYASVFEGDSRWKGLDVPEGELFAWNPESTYVRKQTFFDGMSATPAPVEDIRDARVLALLGDSVTTDHISPAGAFKASSPAGKYLVEHGVEPKNFNSYGSRRGNHEVMVRGTFGNIRLRNMLLASVGEEVRPGGYTYDFLAMKPTTIYEASRDYIDNGVPLVVLGGKEYGTGSSRDWAAKGTAMLGVKAVIVESFERIHRSNLIGMGVLPLQFPEGESAESLGLDGTETYSITGITELNNGVTPKSVHVEATHKDGSKTEFEAVVRIDTPGEADYYRNGGILQYVLRNLMK
>NC_012814.1|WP_004218732.1|1307855_1308107_+|hypothetical-protein
MTLLWSSLFTIIVVGLALWVLYYIIRAAVSAGIKDAYAQMGFIREPDTKEDQLQRRREELQEERVQTIVNSEADRMSGKNGKH
>NC_012814.1|WP_004218733.1|1307041_1307683_-|sugar-O-acetyltransferase
MTNGTSADTREYERMLSGELYIADDPYLKEHSLKRRRLVQEINRSDYDEFDKREALFRELFGSFGEGSYIEPPFRADYGCNTYIGRNFYANTDCIFLDVARIDIGDNVFCGPRVSLLTPYHPIDAQVRNEQLEGGKPISIGNDVWFGGNVTVCPGVTIGDDVVIGAGSVVVKDIPSHCIAVGNPCRPIRAITDADHEQWQRKAREYRAWKEGI
>NC_012814.1|WP_089194267.1|1319721_1321710_-|ABC-transporter-ATP-binding-protein
MQHEVGPLLEVKDLQVDFTTDEGKPIHAVRNSSFSVYPGQWVAIVGESGSGKSTSAMACLGLLPGTGHVVGGSIKLEGQEISQYSPKQFASIRGSKMGLVPQDPMSNLNPVYRIGTQVKEALTANHMDVAHEKRSNLSKALAQADITIKSEGDETFLGSKELPELLEAAGQALVKAGVEGGKYEKRMAYFREEWVPGSETRWRVADDLIKSGVKDDDAWYIAKKYVTGSTMTDRIAGLLDEAGLPDAATRARQYPHEFSGGMRQRALIAIGLACRPELLIADEPTSALDVTVQKRILDHLQELTNSLGTAVLFITHDLGLAAERAQHIVVMYKGQVVESGPSLEVLQNPQHPYTKRLVAAAPSLASQRIISVEEKGEDATSLMDHKVDEDKLEHSDVIIDVDHLTKEFKLPRRREMFKAVDDVSFKIRRGTTLAIVGESGSGKSTVANMVLRLLEPTSGKVLYNGQDIQEFKGKSLLDFRRHVQPVFQNPYGSLDPMYSIYRSIEEPLRIHKIGDKKSRLNRVKELLDMVELPESVMARYPNELSGGQRQRIAIARAMALNPDVIVCDEAVSALDVLVQDQVLHLLNDLQAKQGLTYLFITHDLAVVRQIADDVVVMQHGKLVEHDTTDEVFLHPQQQYTKDLLDAIPGGKLELGLNLEDKA
>NC_012814.1|WP_004218722.1|1321781_1322738_-|ABC-transporter-permease
MTDITNKPLPGQERFVAPLDETPLLSVDNVDESAPATSMWADAWRTLRKNPMFIISGIVILFILFVAIFPGVFTRTNPNYCNLENSLDGSQPGHPFGFDLQGCDVYARVVYGARTSISVGVLTTIIVVAVGTLIGAIAGFFGGWVDAVLSRLVDIFLAIPMLLGAIVVLQMFRTSSSIWKVVLVLALFGWVSTARIARGAVLSSKNLEFNTASTALGSTPMRNLFRHILPNSVAPIIVIGTTSLGSYIVSEATLSFLGIGLPPSVVSWGGDISKAQTVLRTDPMVLFYPSLALAITVLAFIMMGDAVKDALDPKSRTA
>NC_012814.1|WP_004218721.1|1322751_1323678_-|ABC-transporter-permease
MGKYLLRRILQMIPVVLGTTLLVYALVFALPGDPVKAMFGDKPVNEAVAAQIRSEYNLDKPFIVQYLLFLKNALSLNFGNTFAGQPVIDEISRAFPVTLKLALMAFCFEAIFGCVFGAISGLKKGKWYDSVILIVSLLLISVPTFVTGFVGQYFLGVKGHIFPVTAGADPGFFDLLLPAMVLGSVSMAYIIRLARSEISSNIAQDYVRTARAKGMSNTAVTFRHILRNSMIPVVTYLGQDLGALMGGAMITEQIFNIHGIGYLTYQSILKGEANLVVSVVTLLTLVFVICNLIVDMLYAALDPRIRYV
>NC_012814.1|WP_004218720.1|1323977_1325618_-|ABC-transporter-substrate-binding-protein
MKKKTLGLIAGICSLGMMLSLSACGSNGGSSAKGSGDNIITAYNSEPQNALIPGDTNETGGGKVGQLLFANLIAFNAKGEAENEVADSIKPNADSTQYTITLKDGWKFTDGTPVTAESFTKAWSYVANAKNAQKCSSFFSSIKGYDKLQDANSLKGDEQLEGLKVKDDKTFTVDLNAPDSVFPVKIGYLAFAPLPESFYKDPKAFGEKPVGNGMYKLDSWDHGKQIVLSKNADYKGSQKVANNGVTFKIYTSPDSAYADVQAGNLDVMDTVPASNTKTFQSDPDVEPYNKAGSVIQTFTIPADLDHWKTGTEEGQLRRQALSMAINREQIVEKVLNGIGTVATDFTAPVIPGYSKDLKGSDNLKYNPTKAKELWAKADAISKYDGKLTFSFNADGGAQPIYEAVVNQVNNTLGIQASINPMPTFQEFRDAISNRTIKGAFRTAWQPDYPSAENYLYQLYDTAAANGHGSNDGDYSNKDVDKLLDQAASATDQETAIKYYHDAEEILLEQLPAFPLYYSNADGVAAKGVKNFQMDWQNQPIYEEMSK
>NC_012814.1|WP_004218718.1|1325894_1326830_-|tyrosine-recombinase-XerC
MDAQVLMERFIEYLRSNRGLSEHTCMAYRGDILQCLEALDAFGRGNPDDVTLDDLRMWMGRMAHTVGKTSLARKTIAVRSFFTWAYEHGMLAHNPAHALRTPKIDRNLPAVLNEDQAERLMDTVDAEAGEKNAGKSKDDALNAHAKALRDCAMLELLYATGMRVGELVGLDMGSFDWSNRTVRVLGKGNKTRVIPFGAPAQQAVEHWLHGGRPVFANGNSGNAVFIGVRGCRIDQRVVRQVVHEQAEQAGVPDISPHALRHSAATHMLDGGADLREVQEMLGHSSLQTTQRYAHVSIEQLKDRYRQAFPRA
>NC_012814.1|WP_004218716.1|1327068_1327875_+|ABC-transporter-ATP-binding-protein
MSKQARTVTNPDDPVVARAVDLVKTYGDTDSQVTALNHVSVEFQRGELTAIMGPSGSGKSTLMHCMAGLDVPTSGQVFVEDLEVSSMKQKQLTQLRRKEIGFIFQSFNLVPTLTAEENILLPLQIAHRPVDRDWFRKVVGVVGLENRLDHRPSQLSGGQQQRVACARAMMERPSVIFADEPTGNLDSRSSREVLGFLRQCVQDYGQSIVMVTHDPRAASFADRVLVLSDGSITQDMDHPTYDDILAVFAEHDDPDNGPVDVEPAAREA
>NC_012814.1|WP_012619816.1|1327882_1330717_+|FtsX-like-permease-family-protein
MFRIGLRDTKAHFRRFIMSIIAIALGVAFVVGSFCFREMLNDQVSQMMGSNSDADVYVRGATEEKQEPGGSVTSYNSTYNEISTSIIPDIENVDGVASADATMQLGNAVLLDHNGDALTTVGAPTLVIGVDQDAPWRSAHFVSGEYPQTDDEVALLEDTADKAGLKTGDTAKLIVDGEAREMTVSGVFTSPSTQLGAILILARPSFVQHVLQEEGEDTSSIQFIGVYGSKTTPLDEEAQQQLADRINKALPKSADAHAVTGDSVRDDATKSIQDQLGFIQPLILIFAAIALFVGAFIIANTFTMIVRESMRGYALLRSVGASPLQVFASVLIQAVILGLVGSGIGVLLGWGLLELIAKGMTQSGMPLSGSPTPSATDVIVGVIVGVIVTIIGATLPAKTAATAPPIQAMNETVNPEKPVRARGWIGIAMVAVGAAFWVLCYLDADKRVDWQWLKDLGSGWTLGLGAAFVVIGAIVCAPAFVAPAAKVLGWIPSKAFPVTGKLATRNIGRAKRRTANTAAALFIGVAIVSCLGVVASSMKTSVSDLVDNNVNADYVVMAASMTQPISTKAVDAVEDTEGVGASSAVSMLPTVKVTNATKTIMPTTSKVDLFTKIAPVERQDGDAAKAIENGEAVIGRTVANDEHWKIGDTIDLKSENTSVDEQATKQAYEAYQKKIESQVTALQQEAQRLASSGDVSGAQSKAKEAESIVKQAQNTDPKQFVKMKTETKKEQVKIGAIVDDALYSDGIMISLPTAERLTSKDMMMVTQMYVQAKPGANIERLGKNLEKAVKPFYTISVLTRDEFKSSMSSMINSMLAIIYALLALSIIIAIFGIVNTLALNVSERTKEIGLLRAIGTSNGQVRGMLAIEAVILSVFGTLVGIVVGVAAGVVIRIAYESQGMTTLTIPWDQLVLFLIVAILVGLIASISPARRALKHPVLNAVASE
>NC_012814.1|WP_004218710.1|1330861_1331113_+|hypothetical-protein
MRLPERIPVGARVVVRITDGVDEYTGRHQYRDYVGHVRAWDGRTLQLTRDAAANGSRPAQDVDISATDIAILKPVPERPAARR
>NC_012814.1|WP_004218709.1|1331128_1332223_-|prephenate-dehydrogenase/arogenate-dehydrogenase-family-protein
MHEETIKQWDRDNAGEPQIAPEGIECPKHVAIVGLGLIGGSLARRLRESGCHVSAWNHRDHPYANARAAGIDCKDTLEELVAEEPDVLMLCNPLVAMPQVLQTIKPIINPQKTTLSDVGSVKGPVRTQVSEVGLLDCYVGAHPMAGNEHSGWVAADPTLFDDALWAVTFGLHTQYRRVVQIAGMITRGVRNTMIVIDDVTHDREASLISHMPHVLSTALINEMTSDANNAIASALSAGSWRDMTRVALTDPDRTRAMVVENAHNVEELLHRMIDWLSEFANALHEEDETEIRHFFAEGQPYRDYKAQINAGKVSDSTETIFQSLRIDPEHWREQLLKSAQRGEYIVRFTSGHRLIAEQHPSIRS
>NC_012814.1|WP_004218708.1|1332231_1333347_-|chorismate-mutase
MTRQSTRIHYLGPQGSFTHQAAIESAAEASRRLHMDVADFEFVACDTVPQILHAVELGQGWGTIAWENNVEGFVVPNLDLMMDAADAAGFLRVGVNVRFDAFVTERTYRHACEQYASEIAVDDAQIPARDNANAYGAASTPPTIDELAIRDCTAVCAHSHGLAQCRRFAREHGLKPVPAASNAAACRDLQDFQIALGPSICANIYGLHRVAANVGDFDGARTEFLTIAPRSQVVERLRIPRSDPKTEFESVIAFIPLVTGPGVLANLLDVLRDAQLNMVSLISRPVKGRDGTYSFLATLDAAPWDERFVNALVEICEHGDWVRTLAVYPRDERNYPTVSEWMLPAGGVRFEGEPHMANWRESADVRKELLW

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Crispr_ID: NC_012814_4

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_012814_4

1511615-1513233

Unclear

Consensus_repeat	Method
CCCTCAATGAAGCTCCGAAGCCGAGACTTCGGAGAT	CRISPRCasFinder
CCCTCAATGAAGCTCCGAAGCCGAGACTTCGGAGAT	CRT
CCCTCAATGAAGCTCCGAAGCCGAGACTTCGGAGAT	PILER-CR

22 spacers

cas1,cas2,cas7,csb2gr5,cas3,csb3

The CRISPR arrays of NC_012814_4

>merge|NC_012814|4|1511615-1513233|CRISPRCasFinder,CRT,PILER-CR
TCCTCAATGAAGCTCCGAAGCCAAAACTTCGGAGATGCCTCCTGATGGATCTCCACGACGTTGCTGGCCCTTCCTCAATGAAGCTCCGAAGCCGAGACTTCGGAGATGCCATCCCGACTGTGGCGGCGGCGTTCGGTGTCGCCCCTCAATGAAGCTCCGAAGCCGAGACTTCGGAGATGACAGTGCGAACACAGTGCAGTCGGTGACGATCGCGCCCTCAATGAAGCTCCGAAGCCGAGACTTCGGAGATTCGGTCTTCTTGAGCTGGTCGGTGAGTGTCTTGAGCCCCTCAATGAAGCTCCGAAGCCGAGACTTCGGAGATGCAACGCCTTCGTTCGCCTCGTGGACTATCGCGGCCCCCTCAATGAAGCTCCGAAGCCGAGACTTCGGAGATCAGGTTCTCGAGGATGCTCACTATTTCCGTGAGGATGATCCCTCAATGAAGCTCCGAAGCCGAGACTTCGGAGATCTATACCCGTATGCAATGCTGTGCGCGTTGGATGCAAGCCCTCAATGAAGCTCCGAAGCCGAGACTTCGGAGATTGGCGCGAGCAGTATCACCACGTGGCTGCTCAACCGCCCTCAATGAAGCTCCGAAGCCGAGACTTCGGAGATAACGGTTCGATGGTTCGCACAGTGAGTTGTTCACTCCCCTCAATGAAGCTCCGAAGCCGAGACTTCGGAGATTTCGTCTCCTCCCTGCGCCGCTGATTGACCTGTTTCCCTCAATGAAGCTCCGAAGCCGAGACTTCGGAGATGTGATCCCACGTGACGAATCATGGGCCGAGGGATTCCCTCAATGAAGCTCCGAAGCCGAGACTTCGGAGATGTCTCATCAGCGGCGCCACGGGTATCAATCTCAATCCCTCAATGAAGCTCCGAAGCCGAGACTTCGGAGATCCATTCCACCGTTTCGGCGTATTCGCACCACCAGTGCCCTCAATGAAGCTCCGAAGCCGAGACTTCGGAGATATTTCAGGCGGCATCAGACCTTGCGGCTGGGATTCCCTCAATGAAGCTCCGAAGCCGAGACTTCGGAGATGCGTGTGGTGGAAAAACCAGCCCGTCACCGAAGCGGCCCCCTCAATGAAGCTCCGAAGCCGAGACTTCGGAGATTCGCAGGTGAATATCGGTGGCGGCGGCTTGTCGTCCCTCAATGAAGCTCCGAAGCCGAGACTTCGGAGATCGGATAGTATCCTGCGTCGCGTCTCCAATGGCGACCCTCAATGAAGCTCCGAAGCCGAGACTTCGGAGATCTGACAGCATCCTCTCATTCCTCTCGAACGGCGAATACCCCTCAATGAAGCTCCGAAGCCGAGACTTCGGAGATTGTTCGCTTTGATGCGTGTGATTGAGTTCGGCTTCCCTCAATGAAGCTCCGAAGCCGAGACTTCGGAGATTTCGGCGCGTGTTCCTCCGCCGTTGCCGTTGTGGTGGGCCCCTCAATGAAGCTCCGAAGCCGAGACTTCGGAGATGAGGTCATGGTGAAGTCGCGTTCGGTGCCGGTCTTCCCTCAATGAAGCTCCGAAGCCGAGACTTCGGAGATCCGCCTCCCACTCCGCCACGCTGAGCGCCATATCGTCCCCTCAATGAAGCTCCGAAGCCGAGACTTCGGAGAT

>NC_012814|4|3|1511615-1513233|CRISPRCasFinder
TCCTCAATGAAGCTCCGAAGCCAAAACTTCGGAGAT	GCCTCCTGATGGATCTCCACGACGTTGCTGGCCCT
TCCTCAATGAAGCTCCGAAGCCGAGACTTCGGAGAT	GCCATCCCGACTGTGGCGGCGGCGTTCGGTGTCGC
CCCTCAATGAAGCTCCGAAGCCGAGACTTCGGAGAT	GACAGTGCGAACACAGTGCAGTCGGTGACGATCGCG
CCCTCAATGAAGCTCCGAAGCCGAGACTTCGGAGAT	TCGGTCTTCTTGAGCTGGTCGGTGAGTGTCTTGAGC
CCCTCAATGAAGCTCCGAAGCCGAGACTTCGGAGAT	GCAACGCCTTCGTTCGCCTCGTGGACTATCGCGGCC
CCCTCAATGAAGCTCCGAAGCCGAGACTTCGGAGAT	CAGGTTCTCGAGGATGCTCACTATTTCCGTGAGGATGAT
CCCTCAATGAAGCTCCGAAGCCGAGACTTCGGAGAT	CTATACCCGTATGCAATGCTGTGCGCGTTGGATGCAAG
CCCTCAATGAAGCTCCGAAGCCGAGACTTCGGAGAT	TGGCGCGAGCAGTATCACCACGTGGCTGCTCAACCG
CCCTCAATGAAGCTCCGAAGCCGAGACTTCGGAGAT	AACGGTTCGATGGTTCGCACAGTGAGTTGTTCACTC
CCCTCAATGAAGCTCCGAAGCCGAGACTTCGGAGAT	TTCGTCTCCTCCCTGCGCCGCTGATTGACCTGTTT
CCCTCAATGAAGCTCCGAAGCCGAGACTTCGGAGAT	GTGATCCCACGTGACGAATCATGGGCCGAGGGATT
CCCTCAATGAAGCTCCGAAGCCGAGACTTCGGAGAT	GTCTCATCAGCGGCGCCACGGGTATCAATCTCAAT
CCCTCAATGAAGCTCCGAAGCCGAGACTTCGGAGAT	CCATTCCACCGTTTCGGCGTATTCGCACCACCAGTG
CCCTCAATGAAGCTCCGAAGCCGAGACTTCGGAGAT	ATTTCAGGCGGCATCAGACCTTGCGGCTGGGATT
CCCTCAATGAAGCTCCGAAGCCGAGACTTCGGAGAT	GCGTGTGGTGGAAAAACCAGCCCGTCACCGAAGCGGCC
CCCTCAATGAAGCTCCGAAGCCGAGACTTCGGAGAT	TCGCAGGTGAATATCGGTGGCGGCGGCTTGTCGT
CCCTCAATGAAGCTCCGAAGCCGAGACTTCGGAGAT	CGGATAGTATCCTGCGTCGCGTCTCCAATGGCGA
CCCTCAATGAAGCTCCGAAGCCGAGACTTCGGAGAT	CTGACAGCATCCTCTCATTCCTCTCGAACGGCGAATAC
CCCTCAATGAAGCTCCGAAGCCGAGACTTCGGAGAT	TGTTCGCTTTGATGCGTGTGATTGAGTTCGGCTT
CCCTCAATGAAGCTCCGAAGCCGAGACTTCGGAGAT	TTCGGCGCGTGTTCCTCCGCCGTTGCCGTTGTGGTGGGC
CCCTCAATGAAGCTCCGAAGCCGAGACTTCGGAGAT	GAGGTCATGGTGAAGTCGCGTTCGGTGCCGGTCTT
CCCTCAATGAAGCTCCGAAGCCGAGACTTCGGAGAT	CCGCCTCCCACTCCGCCACGCTGAGCGCCATATCGTC
CCCTCAATGAAGCTCCGAAGCCGAGACTTCGGAGAT

>NC_012814|4|1|1511615-1513233|CRT
TCCTCAATGAAGCTCCGAAGCCAAAACTTCGGAGAT	GCCTCCTGATGGATCTCCACGACGTTGCTGGCCCT
TCCTCAATGAAGCTCCGAAGCCGAGACTTCGGAGAT	GCCATCCCGACTGTGGCGGCGGCGTTCGGTGTCGC
CCCTCAATGAAGCTCCGAAGCCGAGACTTCGGAGAT	GACAGTGCGAACACAGTGCAGTCGGTGACGATCGCG
CCCTCAATGAAGCTCCGAAGCCGAGACTTCGGAGAT	TCGGTCTTCTTGAGCTGGTCGGTGAGTGTCTTGAGC
CCCTCAATGAAGCTCCGAAGCCGAGACTTCGGAGAT	GCAACGCCTTCGTTCGCCTCGTGGACTATCGCGGCC
CCCTCAATGAAGCTCCGAAGCCGAGACTTCGGAGAT	CAGGTTCTCGAGGATGCTCACTATTTCCGTGAGGATGAT
CCCTCAATGAAGCTCCGAAGCCGAGACTTCGGAGAT	CTATACCCGTATGCAATGCTGTGCGCGTTGGATGCAAG
CCCTCAATGAAGCTCCGAAGCCGAGACTTCGGAGAT	TGGCGCGAGCAGTATCACCACGTGGCTGCTCAACCG
CCCTCAATGAAGCTCCGAAGCCGAGACTTCGGAGAT	AACGGTTCGATGGTTCGCACAGTGAGTTGTTCACTC
CCCTCAATGAAGCTCCGAAGCCGAGACTTCGGAGAT	TTCGTCTCCTCCCTGCGCCGCTGATTGACCTGTTT
CCCTCAATGAAGCTCCGAAGCCGAGACTTCGGAGAT	GTGATCCCACGTGACGAATCATGGGCCGAGGGATT
CCCTCAATGAAGCTCCGAAGCCGAGACTTCGGAGAT	GTCTCATCAGCGGCGCCACGGGTATCAATCTCAAT
CCCTCAATGAAGCTCCGAAGCCGAGACTTCGGAGAT	CCATTCCACCGTTTCGGCGTATTCGCACCACCAGTG
CCCTCAATGAAGCTCCGAAGCCGAGACTTCGGAGAT	ATTTCAGGCGGCATCAGACCTTGCGGCTGGGATT
CCCTCAATGAAGCTCCGAAGCCGAGACTTCGGAGAT	GCGTGTGGTGGAAAAACCAGCCCGTCACCGAAGCGGCC
CCCTCAATGAAGCTCCGAAGCCGAGACTTCGGAGAT	TCGCAGGTGAATATCGGTGGCGGCGGCTTGTCGT
CCCTCAATGAAGCTCCGAAGCCGAGACTTCGGAGAT	CGGATAGTATCCTGCGTCGCGTCTCCAATGGCGA
CCCTCAATGAAGCTCCGAAGCCGAGACTTCGGAGAT	CTGACAGCATCCTCTCATTCCTCTCGAACGGCGAATAC
CCCTCAATGAAGCTCCGAAGCCGAGACTTCGGAGAT	TGTTCGCTTTGATGCGTGTGATTGAGTTCGGCTT
CCCTCAATGAAGCTCCGAAGCCGAGACTTCGGAGAT	TTCGGCGCGTGTTCCTCCGCCGTTGCCGTTGTGGTGGGC
CCCTCAATGAAGCTCCGAAGCCGAGACTTCGGAGAT	GAGGTCATGGTGAAGTCGCGTTCGGTGCCGGTCTT
CCCTCAATGAAGCTCCGAAGCCGAGACTTCGGAGAT	CCGCCTCCCACTCCGCCACGCTGAGCGCCATATCGTC
CCCTCAATGAAGCTCCGAAGCCGAGACTTCGGAGAT

>NC_012814|4|2|1511616-1513233|PILER-CR
CCTCAATGAAGCTCCGAAGCCAAAACTTCGGAGATG	CCTCCTGATGGATCTCCACGACGTTGCTGGCCCTT
CCTCAATGAAGCTCCGAAGCCGAGACTTCGGAGATG	CCATCCCGACTGTGGCGGCGGCGTTCGGTGTCGCC
CCTCAATGAAGCTCCGAAGCCGAGACTTCGGAGATG	ACAGTGCGAACACAGTGCAGTCGGTGACGATCGCGC
CCTCAATGAAGCTCCGAAGCCGAGACTTCGGAGATT	CGGTCTTCTTGAGCTGGTCGGTGAGTGTCTTGAGCC
CCTCAATGAAGCTCCGAAGCCGAGACTTCGGAGATG	CAACGCCTTCGTTCGCCTCGTGGACTATCGCGGCCC
CCTCAATGAAGCTCCGAAGCCGAGACTTCGGAGATC	AGGTTCTCGAGGATGCTCACTATTTCCGTGAGGATGATC
CCTCAATGAAGCTCCGAAGCCGAGACTTCGGAGATC	TATACCCGTATGCAATGCTGTGCGCGTTGGATGCAAGC
CCTCAATGAAGCTCCGAAGCCGAGACTTCGGAGATT	GGCGCGAGCAGTATCACCACGTGGCTGCTCAACCGC
CCTCAATGAAGCTCCGAAGCCGAGACTTCGGAGATA	ACGGTTCGATGGTTCGCACAGTGAGTTGTTCACTCC
CCTCAATGAAGCTCCGAAGCCGAGACTTCGGAGATT	TCGTCTCCTCCCTGCGCCGCTGATTGACCTGTTTC
CCTCAATGAAGCTCCGAAGCCGAGACTTCGGAGATG	TGATCCCACGTGACGAATCATGGGCCGAGGGATTC
CCTCAATGAAGCTCCGAAGCCGAGACTTCGGAGATG	TCTCATCAGCGGCGCCACGGGTATCAATCTCAATC
CCTCAATGAAGCTCCGAAGCCGAGACTTCGGAGATC	CATTCCACCGTTTCGGCGTATTCGCACCACCAGTGC
CCTCAATGAAGCTCCGAAGCCGAGACTTCGGAGATA	TTTCAGGCGGCATCAGACCTTGCGGCTGGGATTC
CCTCAATGAAGCTCCGAAGCCGAGACTTCGGAGATG	CGTGTGGTGGAAAAACCAGCCCGTCACCGAAGCGGCCC
CCTCAATGAAGCTCCGAAGCCGAGACTTCGGAGATT	CGCAGGTGAATATCGGTGGCGGCGGCTTGTCGTC
CCTCAATGAAGCTCCGAAGCCGAGACTTCGGAGATC	GGATAGTATCCTGCGTCGCGTCTCCAATGGCGAC
CCTCAATGAAGCTCCGAAGCCGAGACTTCGGAGATC	TGACAGCATCCTCTCATTCCTCTCGAACGGCGAATACC
CCTCAATGAAGCTCCGAAGCCGAGACTTCGGAGATT	GTTCGCTTTGATGCGTGTGATTGAGTTCGGCTTC
CCTCAATGAAGCTCCGAAGCCGAGACTTCGGAGATT	TCGGCGCGTGTTCCTCCGCCGTTGCCGTTGTGGTGGGCC
CCTCAATGAAGCTCCGAAGCCGAGACTTCGGAGATG	AGGTCATGGTGAAGTCGCGTTCGGTGCCGGTCTTC
CCTCAATGAAGCTCCGAAGCCGAGACTTCGGAGATC	CGCCTCCCACTCCGCCACGCTGAGCGCCATATCGTCC
CCTCAATGAAGCTCCGAAGCCGAGACTTCGGAGAT

Protein	Signature genes	Signature genes Name	Protein_function
NC_012814.1\|WP_004218204.1\|1499864_1500377_+\|DNA-mismatch-endonuclease-Vsr	unknown	unknown	gnl\|CDD\|226250
NC_012814.1\|WP_004218219.1\|1509954_1511586_-\|CRISPR-associated-endonuclease-Cas4/Cas1	cas1	cd09634_cas1_CAS-I:CAS-II:CAS-III:CAS-V	gnl\|CDD\|376633
NC_012814.1\|WP_004218231.1\|1522732_1525159_-\|anaerobic-ribonucleoside-triphosphate-reductase	unknown	unknown	gnl\|CDD\|236436
NC_012814.1\|WP_004218225.1\|1514757_1519434_-\|2-hydroxyacyl-CoA-dehydratase	unknown	unknown	gnl\|CDD\|226108
NC_012814.1\|WP_004218203.1\|1499184_1499751_-\|NADPH-dependent-FMN-reductase	unknown	unknown	gnl\|CDD\|223508
NC_012814.1\|WP_004218228.1\|1520291_1520693_+\|DUF1304-domain-containing-protein	unknown	unknown	gnl\|CDD\|377753
NC_012814.1\|WP_012754398.1\|1506383_1508021_-\|type-I-U-CRISPR-associated-protein-Cas5/Cas6	csb2gr5	cls000315_csb2gr5_CAS-I-U	gnl\|CDD\|274005
NC_012814.1\|WP_012619748.1\|1501922_1502231_-\|helix-turn-helix-transcriptional-regulator	unknown	unknown	gnl\|CDD\|238045
NC_012814.1\|WP_004218214.1\|1509649_1509943_-\|CRISPR-associated-endonuclease-Cas2	cas2	cd09725_cas2_CAS-I:CAS-II:CAS-III:CAS-V	gnl\|CDD\|187856
NC_012814.1\|WP_004218209.1\|1503339_1506393_-\|hypothetical-protein	cas3	cd09696_cas3_CAS-I-U	gnl\|CDD\|274235
NC_012814.1\|WP_004218212.1\|1508039_1509236_-\|type-I-U-CRISPR-associated-protein-Cas7	cas7	cd09738_cas7_CAS-I-U	gnl\|CDD\|378223
NC_012814.1\|WP_004218205.1\|1501380_1501596_+\|antitoxin-VbhA-family-protein	unknown	unknown	gnl\|CDD\|375921
NC_012814.1\|WP_014482306.1\|1519677_1520295_+\|DUF1211-domain-containing-protein	unknown	unknown	gnl\|CDD\|377696
NC_012814.1\|WP_004269219.1\|1513412_1514684_-\|gamma-glutamylcysteine-synthetase	unknown	unknown	gnl\|CDD\|130503
NC_012814.1\|WP_004218235.1\|1527175_1528201_-\|endonuclease/exonuclease/phosphatase-family-protein	unknown	unknown	gnl\|CDD\|377028
NC_012814.1\|WP_004218229.1\|1520955_1521645_+\|hypothetical-protein	unknown	unknown	unknown
NC_012814.1\|WP_004218233.1\|1526857_1527175_+\|exodeoxyribonuclease-VII-small-subunit	unknown	unknown	gnl\|CDD\|179195
NC_012814.1\|WP_072633051.1\|1521641_1522373_-\|anaerobic-ribonucleoside-triphosphate-reductase-activating-protein	unknown	unknown	gnl\|CDD\|379137
NC_012814.1\|WP_004269218.1\|1502289_1503336_-\|hypothetical-protein	csb3	cd09764_csb3_CAS-I-U	gnl\|CDD\|187733
NC_012814.1\|WP_004218232.1\|1525515_1526814_+\|exodeoxyribonuclease-VII-large-subunit	unknown	unknown	gnl\|CDD\|272979

Protein	Function_ID	Function_description	E-value
NC_012814.1\|WP_004218204.1\|1499864_1500377_+\|DNA-mismatch-endonuclease-Vsr	gnl\|CDD\|226250	COG3727, Vsr, DNA G:T-mismatch repair endonuclease [DNA replication, recombination, and repair].	8.35049e-54
NC_012814.1\|WP_004218219.1\|1509954_1511586_-\|CRISPR-associated-endonuclease-Cas4/Cas1	gnl\|CDD\|376633	pfam01867, Cas_Cas1, CRISPR associated protein Cas1. Clustered regularly interspaced short palindromic repeats (CRISPRs) are a family of DNA direct repeats found in many prokaryotic genomes. This family of proteins corresponds to Cas1, a CRISPR-associated protein. Cas1 may be involved in linking DNA segments to CRISPR.	1.0918e-95
NC_012814.1\|WP_004218231.1\|1522732_1525159_-\|anaerobic-ribonucleoside-triphosphate-reductase	gnl\|CDD\|236436	PRK09263, PRK09263, anaerobic ribonucleoside triphosphate reductase; Provisional.	0
NC_012814.1\|WP_004218225.1\|1514757_1519434_-\|2-hydroxyacyl-CoA-dehydratase	gnl\|CDD\|226108	COG3580, COG3580, Uncharacterized protein conserved in bacteria [Function unknown].	9.43104e-132
NC_012814.1\|WP_004218203.1\|1499184_1499751_-\|NADPH-dependent-FMN-reductase	gnl\|CDD\|223508	COG0431, COG0431, Predicted flavoprotein [General function prediction only].	1.20079e-13
NC_012814.1\|WP_004218228.1\|1520291_1520693_+\|DUF1304-domain-containing-protein	gnl\|CDD\|377753	pfam06993, DUF1304, Protein of unknown function (DUF1304). This family consists of several hypothetical bacterial proteins of around 120 residues in length. The function of this family is unknown.	8.78634e-28
NC_012814.1\|WP_012754398.1\|1506383_1508021_-\|type-I-U-CRISPR-associated-protein-Cas5/Cas6	gnl\|CDD\|274005	TIGR02165, CRISPR-associated_protein_GSU0054_family, CRISPR-associated protein GSU0054/csb2, Dpsyc system. This model represents a CRISPR-associated protein from the Dpsyc subtype (a type I-C variant), named for Desulfotalea psychrophila LSv54. CRISPR systems confer resistance in prokaryotes to invasive DNA or RNA, including phage and plasmids. CRISPR-associated proteins typically are found near CRISPR repeats and other CRISPR-associated proteins, have low levels of sequence identify, have sequence relationships that suggest lateral transfer, and show some sequence similarity to DNA-active proteins such as helicases and repair proteins.	1.03104e-139
NC_012814.1\|WP_012619748.1\|1501922_1502231_-\|helix-turn-helix-transcriptional-regulator	gnl\|CDD\|238045	cd00093, HTH_XRE, Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators.	0.00139643
NC_012814.1\|WP_004218214.1\|1509649_1509943_-\|CRISPR-associated-endonuclease-Cas2	gnl\|CDD\|187856	cd09725, Cas2_I_II_III, CRISPR/Cas system-associated protein Cas2. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; Cas2 is present in majority of CRISPR/Cas systems along with Cas1; RNAse specific to U-rich regions; Possesses an RRM/ferredoxin fold.	8.4419e-18
NC_012814.1\|WP_004218209.1\|1503339_1506393_-\|hypothetical-protein	gnl\|CDD\|274235	TIGR02621, CRISPR-associated_helicase_Cas3, CRISPR-associated helicase Cas3, subtype Dpsyc. This model describes a CRISPR-associated putative DEAH-box helicase, or Cas3, of a subtype found in Actinomyces naeslundii MG1, Geobacter sulfurreducens PCA, Gemmata obscuriglobus UQM 2246, and Desulfotalea psychrophila. This protein includes both DEAH and HD motifs.	1.40435e-50
NC_012814.1\|WP_004218212.1\|1508039_1509236_-\|type-I-U-CRISPR-associated-protein-Cas7	gnl\|CDD\|378223	pfam09617, Cas_GSU0053, CRISPR-associated protein GSU0053 (Cas_GSU0053). This entry is found in CRISPR-associated (cas) proteins in the genomes of Geobacter sulfurreducens PCA and Desulfotalea psychrophila LSv54 (both Desulfobacterales from the Deltaproteobacteria), Gemmata obscuriglobus (a Planctomycete), and Actinomyces naeslundii MG1 (Actinobacteria).	4.74467e-24
NC_012814.1\|WP_004218205.1\|1501380_1501596_+\|antitoxin-VbhA-family-protein	gnl\|CDD\|375921	pfam18495, VbhA, Antitoxin VbhA. VbhT is a bacterial Fic protein of the mammalian pathogen B. schoenbuchensis7,8. It is composed of an N-terminal FIC domain and a C-terminal BID domain. FIC domains are known to catalyse adenylylation (also called AMPylation). This entry represents VbhA, an antitoxin that binds FIC domain (filamentation induced by cyclic AMP) of VbhT and inhibits its activity. It inhibits the adenylylation activity of VbhT by positioning close to the putative ATP-binding site, hence competing with ATP binding.	7.38963e-06
NC_012814.1\|WP_014482306.1\|1519677_1520295_+\|DUF1211-domain-containing-protein	gnl\|CDD\|377696	pfam06736, DUF1211, Protein of unknown function (DUF1211). This family represents a conserved region within a number of hypothetical proteins of unknown function found in eukaryotes, bacteria and archaea. These may possibly be integral membrane proteins.	2.98049e-27
NC_012814.1\|WP_004269219.1\|1513412_1514684_-\|gamma-glutamylcysteine-synthetase	gnl\|CDD\|130503	TIGR01436, Glutamate--cysteine_ligase_chloroplastic, glutamate--cysteine ligase, plant type. This model represents one of two highly dissimilar forms of glutamate--cysteine ligase (gamma-glutamylcysteine synthetase), an enzyme of glutathione biosynthesis. The other type is modeled by TIGR01434. This type is found in plants (with a probable transit peptide), root nodule and other bacteria, but not E. coli and closely related species. [Biosynthesis of cofactors, prosthetic groups, and carriers, Glutathione and analogs].	6.6628e-50
NC_012814.1\|WP_004218235.1\|1527175_1528201_-\|endonuclease/exonuclease/phosphatase-family-protein	gnl\|CDD\|377028	pfam03372, Exo_endo_phos, Endonuclease/Exonuclease/phosphatase family. This large family of proteins includes magnesium dependent endonucleases and a large number of phosphatases involved in intracellular signalling. This family includes: AP endonuclease proteins EC:4.2.99.18, DNase I proteins EC:3.1.21.1, Synaptojanin an inositol-1,4,5-trisphosphate phosphatase EC:3.1.3.56, Sphingomyelinase EC:3.1.4.12, and Nocturnin.	2.71702e-23
NC_012814.1\|WP_004218233.1\|1526857_1527175_+\|exodeoxyribonuclease-VII-small-subunit	gnl\|CDD\|179195	PRK00977, PRK00977, exodeoxyribonuclease VII small subunit; Provisional.	1.25978e-10
NC_012814.1\|WP_072633051.1\|1521641_1522373_-\|anaerobic-ribonucleoside-triphosphate-reductase-activating-protein	gnl\|CDD\|379137	pfam13353, Fer4_12, 4Fe-4S single cluster domain. This family includes proteins containing domains which bind to iron-sulfur clusters. Members include bacterial ferredoxins, various dehydrogenases, and various reductases. The structure of the domain is an alpha-antiparallel beta sandwich.	1.52583e-70
NC_012814.1\|WP_004269218.1\|1502289_1503336_-\|hypothetical-protein	gnl\|CDD\|187733	cd09764, Csb3_I-U, CRISPR/Cas system-associated RAMP superfamily protein Csb3. CRISPR (Clustered Regularly Interspaced Short Palindromic Repeats) and associated Cas proteins comprise a system for heritable host defense by prokaryotic cells against phage and other foreign DNA; RAMP superfamily protein; Might be a catalytically active RNA endoribonuclease.	2.25485e-177
NC_012814.1\|WP_004218232.1\|1525515_1526814_+\|exodeoxyribonuclease-VII-large-subunit	gnl\|CDD\|272979	TIGR00237, exodeoxyribonuclease_VII_large_subunit, exodeoxyribonuclease VII, large subunit. This family consist of exodeoxyribonuclease VII, large subunit XseA which catalyses exonucleolytic cleavage in either the 5'->3' or 3'->5' direction to yield 5'-phosphomononucleotides. Exonuclease VII consists of one large subunit and four small subunits. [DNA metabolism, Degradation of DNA].	7.32407e-149

>NC_012814.1|WP_004218219.1|1509954_1511586_-|CRISPR-associated-endonuclease-Cas4/Cas1
MKYAENNAMKRGEGLEDTLPISLICDFIFCPRRAWLEIQGEKIESLQMERGFHDHRAVDDANGGRGDTDYRAVNVNHQGWGLSGRLDAVRLNEDNGVIIREYKATPVRRSMDVTHAMRIQLALQAACMEDMGYRVDGTEIFFTSHHRIVPVELRKSDYEEAYGSVQEVRKLIECETAPLPFEDDPRCMRCSHAGICLPEERAHNIPEHRIMVKVPDHAVTHLATPGARAYLKSGRMHVSKNGDEITSVPLDSIQALQIHGNVDVSSGLMRELMWRNIPILWCSGTGRLMGWSVSSYGPNGETRVAQHVASHEGRLDLAREFISAKIHNQIVLLRRSDKNNNVLFDMKHIEKSVVNANRIQDILSLEGQAAALYFSQFHHLISVNKRNEWPWLERMRHPAPDPLNALLDYTYSLLLSDCIRAIVSCGLDAHAGFLHSSKRNKPALALDLMEEFRAPIADSVVQTVVNNGEIKRNGFANVMGSVRLRDETRKTLIGAYERRMATELKHPVYAYRASWRRIVEIQARMVLGRLEGSLERYRGIRVR
>NC_012814.1|WP_004218214.1|1509649_1509943_-|CRISPR-associated-endonuclease-Cas2
MNNLMQRYIIAYDIKDDSRRIRVSKLLQSYGNRLQYSVFLMEMREVRLVRMEERLHTLINGAEDSVVIARLDDAKTSESIVFIGSRNYEDVRVPTVI
>NC_012814.1|WP_004218212.1|1508039_1509236_-|type-I-U-CRISPR-associated-protein-Cas7
MMRKLTVQDLNEAAKIGGSNALTEVTSLAPAAGMGSIVAPAKYTAGNGSTYVYEKRWVNDECVDTVLIDSRTSQANRLEDYISRAIEVGHPIFSKMPQVRVRYEMIPGDESSVRYFDDVQLPHRAVDAHIRIAEFSESDKVKYMAARNSSLEDLSAMLAISPVTVMFGCWDSTRNKNQLRIPASFNGEIYAVLADQTHESPIHRAGARIDPVAAGVHLTKNEAKKIAERIKGTMNDKKLSKFASSGDGSTIVIGAIPPSTDANALDGIAVRSITRTHVLSFSMLRAMRFGKGPEGDEAIRVLLAAALINAMVGSNAELHLRENCFLVEADEPKTVLDRRGGKHDDLEMLTLEDADELLAQAYAQAQKKAGIDWHGQIITVQGDPAVIESASAADDDDR
>NC_012814.1|WP_012754398.1|1506383_1508021_-|type-I-U-CRISPR-associated-protein-Cas5/Cas6
MTFAIRIHFLLASYQGASEYGEKESFPTPMRLYQAMVSAAHTVFSSENSQGMLDKRLNAALEWLESNPPEAIRFPEIVSQSPTSHNAIAYRRKADKAPKAERARSAVMYRTDEQGDMILEWKNGPDDEECSTIADLCWEIPFLGGAGSPVRITVEEGFDFPLPDSYMLRPESQSLMEVERARELPCPAPGLHQELMEHYTQANPHPASKIPKDSSTKKDTEVRSEKRLQCVHRSTYSPQKQAKSAVQLPWTRMIIIPARVESNASAWNPRDDELTAWCVALHRLLVRRWGTDVSPYLTGRWSTDSMVKRPANNIAIQVLRKDYASLIADQRIAESLPAFILMIPSEMDAGELRKLGTLVRSLANSRIYYSHSKPALRLGNPIPGEGVHLWSKPRDGMHRIWSPMPFSVNETQAEKSPAGQSRSWTAECNLAVSIGHVFRNVFRGQIAEKRGRGKYWDLIDAVTAGDSFVRILAARTVARPDMGDYVHRMREGFMITASTGLIAFENVIKDEILAIGQSRHFGGGLLIPMDCPESCFTTKGQPKWR
>NC_012814.1|WP_004218209.1|1503339_1506393_-|hypothetical-protein
MEMNATTPNEMLVELYDLFVESLHQGRKPYLWQTRLMREVVNNGQWMKLISAPTGSGKTAVIDVHLFVNALAGLAALDDIPLPKELNHLLKSLSLDAVPRRMAVTVNRRGIVDDQYLEASAACARINDVASLDDDTESEILKLIAVGLYARQYSELMDRQWTFDQLAFQCQEQGKVVCSAQRLRGGLDDKADMRVWRYKPLECQILCGTPDMIGSRLLFSGYGVSDAAKPIEAALLAYDAVIVVDEAQLSRQFAYTAQQIPRIEACIRQGEPLPVSPLQVVVTTATPSGENISNLQDEQSICGVEEADFKIDLELRRRLRTPRPIQVLSVDDKQIATCMAKESIALQERLGGVVVCFVNTVPRASEVVRRLREALGKDAGDNAVRAFVGPMRDYERDQFVQRLDSTEPLYDAIRGDQSAITQTGLKFVVATQTLEAGIDADFSGMISELAPAASLVQRAGRVNRRGLRPEGPVVICCQNSGKIRGPYMKEDLTAAQMWLESLPVEGLTAWSSVLQPPAPAQLERMVLQRLEWWDVENLSHTSEDVFAEHRAAGRPYPADVDLWLRDDLADRVTPDVAVVIRTLPQDDYLAQRLLATTPPDSRELFPVTSYAMLDALQNKLKGRRAFIMRTNSSENGNAVHLLDGQADSDPTLRSGDVLIVDDGARVFSEGIPMLDPFSKDDKHSKKLQDEITSPGDVFNKCQQSMAVLHANREKQPALYEELSEVLRAETDTDETVEAEYQGIDVSKYPNLQEALNSCAINNHGFRIAFVDGFIDGDSSDSSVFIVLQSSDAADGDQLQEIGRFNRQGPVLLDGPGSHQESVGSRAELFAAKLGFDSRLVADIRTAGLHHDDGKKDPRFQTLLRYRMPNVPAEPLAKSMYRSSSWERAKRIELRLDGWRHEQRSAAECWALDSESLQAHDKELVTRLAGTSHGHGRSMFPMNAQQVIPDAIIQTVSEENGDGSQTIHAIRSAAEELFDAGYWQSIMERTNERYGLWGIAFLETLLRAADVTISMEGR
>NC_012814.1|WP_004269218.1|1502289_1503336_-|hypothetical-protein
MSVLRIPADYDDAFSHMLGFGLASILEDAVEDRICRLWWSGRHTLMVETNDEITEMECAHIVRAHAERWHKSQWLNARGSYAGKGKTVATLSPRIGTVAGREEWVALERDRRDAIDSLRTTLDERYIGALGEPSYWSLNRTKATPEIQQKFGASLWEMTPRNRGNEFVTMRLLKLASIITARTAEKVHSGLFGLTNVDELAGTEDSHTPTGLKVPSRTDNARAWCALFGFSNCPVYRSVHYETSPTAGFIRHDSGGGPSWHVVLPLTEKSWTLAKYRSVIRSYALDYVGENALHLDQDSLSDSTVALYAELCRWLRDQGLRYCMLFQRHGTQAKSPEYWLLRGQLIRL
>NC_012814.1|WP_012619748.1|1501922_1502231_-|helix-turn-helix-transcriptional-regulator
MHTTLDLSQYNDVTAYADAVHRPVVHVDYLPTPQAVARRVREAVDDRHLSMEQLAKDAHVSIQAAYSLRDSGLASLSEARRVFAVLDIHVHAYPVEMVPLSL
>NC_012814.1|WP_004218205.1|1501380_1501596_+|antitoxin-VbhA-family-protein
MSVKESDVEMVRAAKAARNTRNLALALHSAEMEGGHVSDVLLHEAHDYANGLIDAATLGLRVCARYGLNDR
>NC_012814.1|WP_004218204.1|1499864_1500377_+|DNA-mismatch-endonuclease-Vsr
MNKARKGAQWYARTIHCPGDTGGVAQSPSHPESPYARGTRSYTMSRIRGKDTSIEKTVRSYLFARGFRFRKNDKRYPGHPDIVLPKYRTIVFVNGCFWHMHEGCESFHMPKSNVEFWAAKLTRNRDRDRRQHEQLRQMGWRVIDVWECELRGDAREARLERLVGQIAEGV
>NC_012814.1|WP_004218203.1|1499184_1499751_-|NADPH-dependent-FMN-reductase
MADKPTIAFVETSLTDGSFEADLAKEIMGIVGDRAEAITIDYEDLPLAGEDPEYPLPEAALAVRDKLGNADAVWVVVSEYKKEIPDSLRNLFDWLSLPSTKDEEGKNVLDQKPVAISGVGGFEELHPRIMVGDLLEDAGMRLFPVEVGLSVPDEAVETGDWAMTGADQEALRTQADDFLTFVSENEVK
>NC_012814.1|WP_004269219.1|1513412_1514684_-|gamma-glutamylcysteine-synthetase
MTAPRVSYAHLLVQPNPRHVRSLVRFFEEGCSAPGTGGFGVEIEHLPVHNADDTAVTYGEPNGVEELLRRLRPYYDSAQEYWQDDHLVGLAREGIAISLEPGGQIETSIGILRKPKDLLELHGQFMREATPILDELDFRLVNYGYQPKSSYADIPLNPKLRYAAMNEYLGRIGQFGPCMMRASASTQVSIDYTSERDAIDKMRLGTAIGPILAWFFRNTPYFEGAPNPWPLCRQRMWDYLDVQRTNVTPGLYDERFSWEDYAADVLSTPLMFADLTHTPEAEGASVHGTEFTAFYTTAADLYPDRELNAYEINHVLSTHFNDVRLKNFIEMRHWDSLPIERAELLTQIVSNLFYDVERRTSLESYFSGLTGEDVHAAKAVLQARGGDAKPYDQPMDYWAEVLGVGDALADVPGDAKWPEVRQG
>NC_012814.1|WP_004218225.1|1514757_1519434_-|2-hydroxyacyl-CoA-dehydratase
MASLVQEPSSISQTLNTEPRPLRIGLDIGSTTVKAVVLDDSDSLDATLFADYRRHHANVRATMEGLLRDIRAHLAELGRADEPVRLAITGSGGLALADAVHVPFVQEVIAETRAIDEAIPQADVIIELGGEDAKITYLKPTPEQRMNGSCAGGTGAFIDQMSTLLDTDAAGLNEMAKYYQTLYPIASRCGVFAKTDLQPLINDGAAKPDLAASIFTAVATQTIAGLASGRPIHGTVVFLGGPLFFMSELREAFRRALDGKVDEFITPTDAHLYVAYGAALAVGEPGQIEHADEYPARSLDDIINALEDLKNLPSNTATMPPLFDTAADRDAFNARHHREHVHVGTLEGARGPHFLGIDAGSTTIKATLVNDDREIVWSSYATNDGSPLTAAIEIVKRIQSELPSDAWIARSCATGYGEGLITTGLHLDEGVVETMAHYRGAEMVSPGVTAVIDIGGQDMKYLAVTDGVIDSIAVNEACSSGCGSFLQTFARSMGLTIEEFTQAALASEHPVDLGSRCTVFMNSSVKQAQKEGASIEDIAAGLCYSVVRNALYKVIKLRDSGELGSTVVVQGGTFLNDAVLRAFELLTEREVTRPNIAGLMGAYGAALTARMHYDDIADDTDGDTDAAGVHVACIDGVDHTVSSILHGTALDELSMTTERDVCKLCQNHCKLTITTFHDGSRYVTGNRCERGGDAKRKRSDRPNLYDFKYKRAFAYRRLTDKKATRGEIGIPRVLNMYENYPFWFTLLTSLGFKVVISGRSNHELFETGIESIASENICYPAKLVHGHIKWLLNKGIRTIFYPCVSFEDDLVPESDNHYNCPVVANYPVVIEANMPELRADGIRFMRPYFNLSKHSLMVDRIVEEFAWAGVTREEAEAAVAAAYAEDTVFKHDVQQEGVRALAYMKEHNCRGIVLAGRPYHVDPEVNHGIPETICSLGMVVLSEDSVSWLDPNDVPALTAYLAEDETDPAAHTSEGFRHVNDRKLTTMPLRVMNQWAYHARLYRAAQFVASWPGLELVQLNSFGCGLDAVTTDQVSEILADKADVYTMLKIDEVSNLGAAKIRLRSLKAAVEERERNAQRAATPAASAGTFRHTGTAAPTPGRQILLDAVMGRQAGGAQQNRQSATMSAYANRVPFGKDMRRDYTIVAPQMSPIHFRLVEAAIRASGYKFDVLEHASKTDVETGLKYVNNDACYPAIMTVGQLVEAIKSRRYDPDSTALAISQTGGMCRATNYFALIRKALVDAGYPQIPVIAISTQGFVDNPGFTPTVPLLHRAAKSLIIGDLLMKCLYRVRPYEANPGSANRLYERWNVIVRETLLNHGMSKTAKMLYGRAYWPYAKLVAKIVESFDALPLRDVERKVRVGVVGEILVKYQPDANNHVVEVIESQDCEAVVPGIIDFMTMRPYINDWNEHNLGTGRNKALYTAFKGVIHTYMKPVNDALESSGGKFEKDLPMDQLVAKAQTVTSIGVQAGEGWLLTGEIVELIESGCPNIICAQPFACLPNHVTGRGMFGKIRRLYPQANIVSIDYDPGASEANQLNRIKLMIAAAKKNAAAGRSSV
>NC_012814.1|WP_014482306.1|1519677_1520295_+|DUF1211-domain-containing-protein
MIGSRRVWECAMSKERVVAFTDAVLAIIMTILVLDLDKPDPLTWSGFGKLWPQFLAYAFSFFWLGSMWVHLHIEWSGVKLVDQPVLWTSITLLFFCSLIPYSTSLVAGNVLSWDLAIKIVGIMITLTIWPPAMLVFTLAAAMFLFLKSASAERRMQVKIKKDALANNGMATPDDVAAVGGSAEEYLAAIEAAKQAAKEADEGDKQ
>NC_012814.1|WP_004218228.1|1520291_1520693_+|DUF1304-domain-containing-protein
MNTALITASIFAMLAGLLHVYIFVMESFLWTSRSTRETFSMGADEAEQTKEMAFNQGFYNLFLAIMSIGGAIVLWCGVTVVGVTLMTAGSASMFCAALVLLCTAPDKHSAAIKQIFFPALTLIALLVALILFA
>NC_012814.1|WP_004218229.1|1520955_1521645_+|hypothetical-protein
MAIITVVAIVGGVVGGIIYKNKHDEAYARCQTAVSEFSEARKALLDTTSDSPALQKLVRNALGVDKILDAAADAASAAEGTVAQQGCAANATIIQLNLVANTLNSATESLRKSTAQIVRGASADTDNTGDESESAASSDTEDVAQAKRNLQEAIDQGRALLDTLKQRYADSAVGRQLTAGFEAALDLAQEKFDESGIKDSRYYKAAQATLDEATNAVNAWIDRQAQKAD
>NC_012814.1|WP_072633051.1|1521641_1522373_-|anaerobic-ribonucleoside-triphosphate-reductase-activating-protein
MNDSANGTWRSTGKPRLHDFAAGETGRGPAIPTPMSNNPKPGQWTNRMSHNMIADYKRFLMTDGEGIRCSLYVSGCPFHCVECYNSSIWDFQAGHEYNDKLEAQIMDDLAQSFVQGITFLGGEPLLNTGVLLPLARKIRERFGHTKDIWCWTGYTWEELMRDGETQDKLDLLHEIDILVDGRYIKTLHDSLLQFRGSRNQRILDVQESFRQGKPVVWAKLHDQERFIPEIYGKERAAGEGDAS
>NC_012814.1|WP_004218231.1|1522732_1525159_-|anaerobic-ribonucleoside-triphosphate-reductase
METQILGDTLSRTVVGDGDDVFEGMFTDRVLVEKRDGRVVDFDPVNIVVAVKSAFADLDKEVGPQEERMILDIANQIEGEIRERYNGPAKIEDIQNLVEHALIEDHLYEVARTYTNYRLNKDIQRAKATDINEAVSRLVNRDESLVRENANKDSNVYATQRDLLAGAVSKASAFSMLPDAVANAHMKGDIHFHDADYSPFTSMNNCSLPDFGDMLKHGFALGNAMMDSPKSIGTASTQITQIIKDIAGAQYGGQTVNRADEMLEEYAKRDYVKNLDMAHAMIPDSTPIEVARDMVAGLKAQEPRWLHFENREPLPADEAFDTNAPELEQIREIYAKIMTRKAIYDAMQTMEYQINSNRVSNGQTPFVTVGFGLGMSWFAREIQRAILLNRIRGLGKERHTAIFPKLVFTVKHGVNADEGDPNYDLKQLALECATKRMYPDVVFYDNIVKITGSFKAPMGCRSFLQGWIDPKTGKDVEDGRMNLGVVTVNVPRIALESHGDVERFWKIFDERMEVAHQALQFRIMRCKQATPVNAPTLFRYGAFGRLETNENVDQLFRNERATVSLGYIGLYEATAVFFGKDWMRDHAWDPEGKDFALSIVRRMNELCKQWSKAEGYHYSVYSTPAESLTDRFNRMDRKKFGKVEGVTDHDFYTNSFHYPVWLQPTPMEKLDYEKDFPYYASGGFINYCEFPCLQANPKALEAVWDYAYNIGIGYLGTNTPIDHCFVCGFEGDFAPTEEGFKCPECGNSDPDKCNVTKRTCGYLGNPVQRPMVHGRHEEIAHRVKHMAGETGHVTLADGETREWFEETK
>NC_012814.1|WP_004218232.1|1525515_1526814_+|exodeoxyribonuclease-VII-large-subunit
MVFNNGYQTGYRQGYAPAPAAGPNELPRMAAQTTAENPWPVSMVSQKFHSAVERWPAVWMEGQIIEINTRRSGSAYLTLRDNDQDVSMSVLGFGAFAQMARDYKQGDRVVVHGKADLYVKSTRLSLRADMIKRVGAGNLQEQINQLRMRLKGEGLFDESRKVALPEFPKNIGLICAPQARAEGDVVMNVNLRWPGVRFTIVHAHVQGEQCPPDIVSAIQQLDADPNVDVIIVARGGGSFEDLMGFSDERVVRATAACATPIISAIGHEDDWTLIDLAADVRASTPTDAAKRVVPDVREQQQLITEGINRMRTFIANRAGNEERLVEGYANRPSLTQPLTMLIPHERDIADAVSAMRNGLRRIVDEEQMQVERLAATLRALSPQSTLDRGYAVLQNADGAIIDDASQVQVGDELTLTLRRGKVVSQAQAVYDE
>NC_012814.1|WP_004218233.1|1526857_1527175_+|exodeoxyribonuclease-VII-small-subunit
MAEDMEITEVSETEPQTASSLSQEERERIAQLPYEQARDELIQAVRALENGGLSLEDSMKQWELGEALAQRAQSLLSTIRAKLDAAQQAQAQTANTAGTQSNLES
>NC_012814.1|WP_004218235.1|1527175_1528201_-|endonuclease/exonuclease/phosphatase-family-protein
MAMMRKHRVLGAIAGLLALASLCSCALRLLPVDLQTLPYVSVVLAATPWFAIVSVVSLVLALISTRWVTAIVAGVCLAIQVCWQLPFYHNGTPLSGSALSSQSLPRADTADAVARLMTCNVYKGHADAAAIVNAVRDNHVEVLALQETTPDFLKRLEEAGISQLLPYSQTSSADGYFGNALFSALPFENPSQTDVDSIASYMPGGTVGFDNGAIPVRFVSVHTQSPTEGRFEKWSRSIAELKQLNEHPDTDYILMGDFNSTWDHAVFRDMLGTRFQDAAEVSGHGLVFTWPADRKYLPAFAGIDHIVTSKDVTIGQVNSLTIPGSDHRALLATVDVSGLRH

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Crispr_ID: NC_012814_5

CRISPR_ID

CRISPR_location

CRISPR_type

Repeat_type

Spacer_info

Cas_protein_info

CRISPR-Cas_info

NC_012814_5

1911846-1911936

Orphan

Consensus_repeat	Method
TTGGCGTCCATGTCACGCGCGGAATCGAT	CRISPRCasFinder

1 spacers

The CRISPR arrays of NC_012814_5

>merge|NC_012814|5|1911846-1911936|CRISPRCasFinder
TTGGCGTCCATGTCACGCGCGGAATCGATCGTCCGAGAGTGGATTCGCGGATTGTCTTGATCTTGGCGCCCATGTCACGCGCGGAATCGAT

>NC_012814|5|4|1911846-1911936|CRISPRCasFinder
TTGGCGTCCATGTCACGCGCGGAATCGAT	CGTCCGAGAGTGGATTCGCGGATTGTCTTGATC
TTGGCGCCCATGTCACGCGCGGAATCGAT

Protein	Signature genes	Signature genes Name	Protein_function
NC_012814.1\|WP_004218996.1\|1924225_1926475_+\|hypothetical-protein	unknown	unknown	unknown
NC_012814.1\|WP_004218982.1\|1908744_1910193_-\|DUF4032-domain-containing-protein	unknown	unknown	gnl\|CDD\|379077
NC_012814.1\|WP_004218969.1\|1895774_1897997_-\|alpha-galactosidase	unknown	unknown	gnl\|CDD\|307952
NC_012814.1\|WP_004218991.1\|1920858_1921485_+\|LytR-C-terminal-domain-containing-protein	unknown	unknown	gnl\|CDD\|379163
NC_012814.1\|WP_004218985.1\|1911957_1912980_+\|potassium-channel-family-protein	unknown	unknown	gnl\|CDD\|369572
NC_012814.1\|WP_004218984.1\|1910400_1911534_-\|sn-glycerol-3-phosphate-ABC-transporter-ATP-binding-protein-UgpC	unknown	unknown	gnl\|CDD\|236947
NC_012814.1\|WP_004218990.1\|1919830_1920787_+\|4-diphosphocytidyl-2C-methyl-D-erythritol-kinase	unknown	unknown	gnl\|CDD\|224858
NC_012814.1\|WP_004218986.1\|1913049_1915167_+\|protein-kinase	unknown	unknown	gnl\|CDD\|270916
NC_012814.1\|WP_004218977.1\|1903504_1904086_-\|dCTP-deaminase	unknown	unknown	gnl\|CDD\|234753
NC_012814.1\|WP_004218987.1\|1915546_1916584_+\|hypothetical-protein	unknown	unknown	gnl\|CDD\|235012
NC_012814.1\|WP_004218973.1\|1898771_1900844_+\|Na+/H+-antiporter	unknown	unknown	gnl\|CDD\|223104
NC_012814.1\|WP_004218995.1\|1923218_1924223_+\|NUDIX-hydrolase	unknown	unknown	gnl\|CDD\|239645
NC_012814.1\|WP_004218988.1\|1917251_1918799_+\|G5-domain-containing-protein	unknown	unknown	gnl\|CDD\|226111
NC_012814.1\|WP_004218975.1\|1901895_1903455_-\|hypothetical-protein	unknown	unknown	gnl\|CDD\|380155
NC_012814.1\|WP_004218989.1\|1918940_1919834_+\|16S-rRNA-(adenine(1518)-N(6)/adenine(1519)-N(6))--dimethyltransferase-RsmA	unknown	unknown	gnl\|CDD\|234708
NC_012814.1\|WP_004218979.1\|1904295_1907286_-\|cation-translocating-P-type-ATPase	unknown	unknown	gnl\|CDD\|223550
NC_012814.1\|WP_004218974.1\|1900914_1901853_-\|esterase	unknown	unknown	gnl\|CDD\|223477
NC_012814.1\|WP_004218981.1\|1907600_1908596_+\|23S-rRNA-(guanosine(2251)-2'-O)-methyltransferase-RlmB	unknown	unknown	gnl\|CDD\|223640
NC_012814.1\|WP_004268865.1\|1921614_1923033_-\|CCA-tRNA-nucleotidyltransferase	unknown	unknown	gnl\|CDD\|131739
NC_012814.1\|WP_004218971.1\|1898112_1898622_-\|nucleoside-deaminase	unknown	unknown	gnl\|CDD\|223663

Protein	Function_ID	Function_description	E-value
NC_012814.1\|WP_004218982.1\|1908744_1910193_-\|DUF4032-domain-containing-protein	gnl\|CDD\|379077	pfam13224, DUF4032, Domain of unknown function (DUF4032). This presumed domain is functionally uncharacterized. This domain family is found in bacteria, and is approximately 170 amino acids in length. The family is found in association with pfam06293.	6.16001e-95
NC_012814.1\|WP_004218969.1\|1895774_1897997_-\|alpha-galactosidase	gnl\|CDD\|307952	pfam02065, Melibiase, Melibiase. Glycoside hydrolase families GH27, GH31 and GH36 form the glycoside hydrolase clan GH-D. Glycoside hydrolase family 36 can be split into 11 families, GH36A to GH36K. This family includes enzymes from GH36A-B and GH36D-K and from GH27.	5.11586e-158
NC_012814.1\|WP_004218991.1\|1920858_1921485_+\|LytR-C-terminal-domain-containing-protein	gnl\|CDD\|379163	pfam13399, LytR_C, LytR cell envelope-related transcriptional attenuator. This family appears at the C-terminus of members of the LytR_cpsA_psr, pfam03816, family.	3.21486e-16
NC_012814.1\|WP_004218985.1\|1911957_1912980_+\|potassium-channel-family-protein	gnl\|CDD\|369572	pfam07885, Ion_trans_2, Ion channel. This family includes the two membrane helix type ion channels found in bacteria.	1.60974e-15
NC_012814.1\|WP_004218984.1\|1910400_1911534_-\|sn-glycerol-3-phosphate-ABC-transporter-ATP-binding-protein-UgpC	gnl\|CDD\|236947	PRK11650, ugpC, sn-glycerol-3-phosphate ABC transporter ATP-binding protein UgpC.	2.85165e-175
NC_012814.1\|WP_004218990.1\|1919830_1920787_+\|4-diphosphocytidyl-2C-methyl-D-erythritol-kinase	gnl\|CDD\|224858	COG1947, IspE, 4-diphosphocytidyl-2C-methyl-D-erythritol 2-phosphate synthase [Lipid metabolism].	1.14612e-58
NC_012814.1\|WP_004218986.1\|1913049_1915167_+\|protein-kinase	gnl\|CDD\|270916	cd14014, STKc_PknB_like, Catalytic domain of bacterial Serine/Threonine kinases, PknB and similar proteins. STKs catalyze the transfer of the gamma-phosphoryl group from ATP to serine/threonine residues on protein substrates. This subfamily includes many bacterial eukaryotic-type STKs including Staphylococcus aureus PknB (also called PrkC or Stk1), Bacillus subtilis PrkC, and Mycobacterium tuberculosis Pkn proteins (PknB, PknD, PknE, PknF, PknL, and PknH), among others. S. aureus PknB is the only eukaryotic-type STK present in this species, although many microorganisms encode for several such proteins. It is important for the survival and pathogenesis of S. aureus as it is involved in the regulation of purine and pyrimidine biosynthesis, cell wall metabolism, autolysis, virulence, and antibiotic resistance. M. tuberculosis PknB is essential for growth and it acts on diverse substrates including proteins involved in peptidoglycan synthesis, cell division, transcription, stress responses, and metabolic regulation. B. subtilis PrkC is located at the inner membrane of endospores and functions to trigger spore germination. Bacterial STKs in this subfamily show varied domain architectures. The well-characterized members such as S. aureus and M. tuberculosis PknB, and B. subtilis PrkC, contain an N-terminal cytosolic kinase domain, a transmembrane (TM) segment, and mutliple C-terminal extracellular PASTA domains. The PknB subfamily is part of a larger superfamily that includes the catalytic domains of other protein STKs, protein tyrosine kinases, RIO kinases, aminoglycoside phosphotransferase, choline kinase, and phosphoinositide 3-kinase.	3.82293e-72
NC_012814.1\|WP_004218977.1\|1903504_1904086_-\|dCTP-deaminase	gnl\|CDD\|234753	PRK00416, dcd, deoxycytidine triphosphate deaminase; Reviewed.	4.37887e-92
NC_012814.1\|WP_004218987.1\|1915546_1916584_+\|hypothetical-protein	gnl\|CDD\|235012	PRK02201, PRK02201, putative inner membrane protein translocase component YidC; Provisional.	0.000728081
NC_012814.1\|WP_004218973.1\|1898771_1900844_+\|Na+/H+-antiporter	gnl\|CDD\|223104	COG0025, NhaP, NhaP-type Na+/H+ and K+/H+ antiporters [Inorganic ion transport and metabolism].	2.14183e-78
NC_012814.1\|WP_004218995.1\|1923218_1924223_+\|NUDIX-hydrolase	gnl\|CDD\|239645	cd03673, Ap6A_hydrolase, Diadenosine hexaphosphate (Ap6A) hydrolase is a member of the Nudix hydrolase superfamily. Ap6A hydrolase specifically hydrolyzes diadenosine polyphosphates, but not ATP or diadenosine triphosphate, and it generates ATP as the product. Ap6A, the most preferred substrate, hydrolyzes to produce two ATP molecules, which is a novel hydrolysis mode for Ap6A. These results indicate that Ap6A hydrolase is a diadenosine polyphosphate hydrolase. It requires the presence of a divalent cation, such as Mn2+, Mg2+, Zn2+, and Co2+, for activity. Members of the Nudix superfamily are recognized by a highly conserved 23-residue nudix motif (GX5EX7REUXEEXGU, where U = I, L or V), which forms a structural motif that functions as a metal binding and catalytic site.	3.99945e-50
NC_012814.1\|WP_004218988.1\|1917251_1918799_+\|G5-domain-containing-protein	gnl\|CDD\|226111	COG3583, COG3583, Uncharacterized protein conserved in bacteria [Function unknown].	2.68164e-36
NC_012814.1\|WP_004218975.1\|1901895_1903455_-\|hypothetical-protein	gnl\|CDD\|380155	NF012221, MARTX_Nterm, MARTX multifunctional-autoprocessing repeats-in-toxin holotoxin RtxA. This model describes the N-terminal 1900 amino acids of MARTX family multifunctional-autoprocessing repeats-in-toxin holotoxins, which contain both repeat regions that facilitate their entry into eukaryotic target cells, and multiple effector domains.	0.000288677
NC_012814.1\|WP_004218989.1\|1918940_1919834_+\|16S-rRNA-(adenine(1518)-N(6)/adenine(1519)-N(6))--dimethyltransferase-RsmA	gnl\|CDD\|234708	PRK00274, ksgA, 16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase RsmA.	7.3034e-125
NC_012814.1\|WP_004218979.1\|1904295_1907286_-\|cation-translocating-P-type-ATPase	gnl\|CDD\|223550	COG0474, MgtA, Cation transport ATPase [Inorganic ion transport and metabolism].	0
NC_012814.1\|WP_004218974.1\|1900914_1901853_-\|esterase	gnl\|CDD\|223477	COG0400, COG0400, Predicted esterase [General function prediction only].	9.25712e-25
NC_012814.1\|WP_004218981.1\|1907600_1908596_+\|23S-rRNA-(guanosine(2251)-2'-O)-methyltransferase-RlmB	gnl\|CDD\|223640	COG0566, SpoU, rRNA methylases [Translation, ribosomal structure and biogenesis].	2.52914e-72
NC_012814.1\|WP_004268865.1\|1921614_1923033_-\|CCA-tRNA-nucleotidyltransferase	gnl\|CDD\|131739	TIGR02692, putative_tRNA_nucleotidyltransferase, tRNA adenylyltransferase. The enzyme tRNA adenylyltransferase, also called tRNA-nucleotidyltransferase and CCA-adding enzyme, can add or repair the required CCA triplet at the 3'-end of tRNA molecules. Genes encoding tRNA include the CCA tail in some but not all bacteria, and this enzyme may be required for viability. Members of this family represent a distinct clade within the larger family pfam01743 (tRNA nucleotidyltransferase/poly(A) polymerase family protein). The example from Streptomyces coelicolor was shown to act as a CCA-adding enzyme and not as a poly(A) polymerase. [Protein synthesis, tRNA and rRNA base modification].	0
NC_012814.1\|WP_004218971.1\|1898112_1898622_-\|nucleoside-deaminase	gnl\|CDD\|223663	COG0590, CumB, Cytosine/adenosine deaminases [Nucleotide transport and metabolism / Translation, ribosomal structure and biogenesis].	2.26822e-59

>NC_012814.1|WP_004218984.1|1910400_1911534_-|sn-glycerol-3-phosphate-ABC-transporter-ATP-binding-protein-UgpC
MAEVIFDHVTRIYPGNDKPSVDDLNLDIKDGEFLVLVGPSGCGKSTTLRMLAGLEEVNKGRILIGGKDVTTMQPKDRDIAMVFQNYALYPHMTVADNMGFALKIAGTPKDEIRKRVEKAAEILDLTEFLDRKPKALSGGQRQRVAMGRAIVREPKVFLMDEPLSNLDAKLRVQTRTQIAALQRQLGVTTLYVTHDQTEALTMGDRIAVIKLGILQQVGAPTELYDRPANVFVAGFIGSPSMNINTHPVVNGKAQIGADTMELPKEALDKLTPEDKNEIIVGFRPEDASLAAPDEANAFSLKVVNVEDLGSDGYIYGNIITDDSVAQKTTDTLMSDQNQLTTIRVNPRVLPKVGDVVKIKVNPAKMHLFSPSTELRLN
>NC_012814.1|WP_004218982.1|1908744_1910193_-|DUF4032-domain-containing-protein
MGITDNPQLDPRALKATSVKAEDPATPGPGPSTLKITAASSDPKMFTLPWEKPLATWPPELLVNLPRGISRHIVRFVHVGDEVYAMKEITRTVAEREYELLRQLQKLNLPTVQPIAVVTGRHDDNGEPLEAILVTKHLRFSMPYRALFARTLRPDTAERLIDALAVLMVRLHLAGFYWGDVSLSNVLFLKDADAFSAFLVDAETGDLQIELTAGQREYDIDLARTNIIGELMDLSSGELLPPDVDEISIGNRLVDRYHSLWSALTDTDNFSPNEMWKIEKRVNRLNELGFDVDELEMKTAEDGKRVLVRPRVVDAGYANRRLLRLTGLDVQENQARRLLNDLDAYRASSWREGEDLEIVATDWMREVFEPTVRMIPREYRSQIEPAQFFHEVLDHRWYMAEKAGHDVPMAEAVQSYIKNVLPQYQLDTKTVNELNADADAGVVDDEYTYDDASNNGAHTAPAAGHDDGYNPEDDPDAAVWAH
>NC_012814.1|WP_004218981.1|1907600_1908596_+|23S-rRNA-(guanosine(2251)-2'-O)-methyltransferase-RlmB
MATKKGPTKGSGGKHRNSLRGKGPTPKAEDRVYHKAYKAKKQAEKRQRSDPRLAARRRAAHFTSNSDDLVIGRNSVLEALRVGVPASVLYVANRIEHDDRTREIVRLAGQHGLNLLEADRLEMDRIARSGNHQGVILKADPFQYSSLHELVERAERKARAMEMADSKASRLSARPLFIALDGITDPQNLGAVIRSAAAFGVNGVILPERRSASVNAAAWKVSAGAAAHMPIARVVNLTKAIEALKERGYYSIGLDGGGSKLVGETGFETDPLVVVLGSEGKGLSRLTREACDAIASIPITSAVESLNASVAAGIALYATVNARRKAGEAAN
>NC_012814.1|WP_004218979.1|1904295_1907286_-|cation-translocating-P-type-ATPase
MDDRIIDPSALNREPHVEPADAEESKEVKAQEALLHDVDPSLASADEVAEALNVDTHTGLSSEEAKRRLEKFGANELASAPPVPKWKKFLQQFQDPLVYLLLAATAISLVAWIIEKVNAAPGAEGGEALPFDAIVIVLILIVNAVLGYVQEAKADEAVNALSEMTAPTSNVLRNGRVERIATTDIVPGDVLVLGEGDTVPADGRLFAAASLRIAEASLTGESVPVGKKPETLEKAKALGDRSNMVFNGTSVTQGTGRAIVTGTGMNTQVGKIADLLQSTEDDTTPLQKEMNHVSKILGIAVCIIAVVVLVALAVLEGFHSVHDVIDSLLLAVSLAVAAVPEGLATILTVVLALGVQRMAAHHAIVKKLHSVETLGSASVICSDKTGTLTRNEMTVERVVVPSGEVELTGTGYAPEGDMVSLNGDAVPENIAQEVYATLGAGTLANDGELREGPKPGTWEIVGDPTEVSLVVAARKTHADKRFHHFTRVAEIPFTSERKRMSVITKNDTDSGKLTVFAKGAPDVLLSYCDRIFVNGAVRKLTEGDRQDILKKVEELSREAYRTLGEAYRPLETASLSEVPGIRTNAAGDVSDISEQADVIEHQLVWTGMVGIIDPPRVEVRDAVAEAHRAGVRTVMITGDHPLTAARIASDLGIIEQGGKALTGDELDSMDEKQLDKATSEVSVYARVAPEHKLKIVESLQRQGNIAAMTGDGVNDAPAVKAADIGVAMGITGTEVTKQSAKMILADDNFSTIVAAVREGRGIFDNIRKFLRYLLSSNVGEVFTVFLGVVLAGFLGIKNPDSVGVTVPLLATQLLWINLLTDAAPALAMGVDPTTEDVMNRKPRKLTDRVIDGAMWGDIVYIGLIMAIVTLIGMDMHLSGGVFTDRSVDALGHDAQMVEARTMGFTILVFAQLFNAIASRSHLQSAFKGLFSNKWLWGAIALSIVLQLLVIYVPWLNTAFGTTPLPPMAWLECIGLAAIVLVASEIRKIFLRMRATH
>NC_012814.1|WP_004218977.1|1903504_1904086_-|dCTP-deaminase
MLLSDRDIRAAHAEGHISLDPWTDEMVQPASIDVRLDRFFRLFNNHAYTYVDPAENQGELTEQFEVGPDEPWILHPGEFALGSTWEYVKIDETLAARLEGKSSLGRLGILTHSTAGFIDPGFEGHITLELSNVSTLPVKLWPGMKIGQMCFFQLSSPSEHPYGSETTGSHYQGQRGPTPSRSYQNFYRAQITD
>NC_012814.1|WP_004218975.1|1901895_1903455_-|hypothetical-protein
MTDSGNPSDLQFPVSPEPRDFDVTHVVDKDALEFPSMDDDPSHAAAHESQLQSAGSANTAAIPAPPVNGHPHDHARRTARSGAHDATPTPDETPADSAALTLAASQPSAGRHAANTVNGASAGDAAPTQLFTSPHDDVLAGVSVNPPLPAEEPTRVVSSEWEQIVDSQTSVMPPAAPAAMPPAIPPTDADGNADGSGDEPDEEAPHHSANGGGKSHTKLIAGIVVGVLVIALIAGGIAWWSSSRRNNAQRNAYTLCQNTRDSYDDAHTALAAALKDANALTSTPTDQVADAKTLDTLKSAVADAEKLDQQSVAECAVDANTAAIEKTTDSLRNTANEITKAKSALDAATKAVNDSKNMQSQSAARDELTKAIDDAQKILDASANAVTDEQVRTDLENRIADARKLADGQNLNAEDVTAMVKTLTDAGTAVQQSQTEYANQQAATAQQAAEEAQRQAEAQAQAAQQAQQNAAQAQQQNAQTTTPDTSDAGTAGDGTTGAGATGTDGETTGNGGTPANGAQ
>NC_012814.1|WP_004218974.1|1900914_1901853_-|esterase
MSTADDTPNPDDPFEPSDDPEHLDDLSRELDDLVDFANLEREMTEAANTTPSGPYAGQSAGERKRMEPPVGRVASVVPGHFGDRLTVTEALASRGGGNAQPNRPLFVCLHGWGSNEDDLAGIMRYVAPYSDFVSLRAPLVLQEASPRGFAMQQGAYSWFHDAVPVGDDLDYDAYAAACAIDDWVTTNVGENRDVVPIGFSQGGTLAVELLRVHPQRYRAAISLSGFVAPGNVPATTPYDDILADLNIPVFYGYGELDTVLPKYMIYETIAWLEEHTWLTARGYRGLDHAVSMEEFSDLRQWLLDQDIASGII
>NC_012814.1|WP_004218973.1|1898771_1900844_+|Na+/H+-antiporter
MSVLILILCILGAVLLSSFLSRFLPRISTPLVQIVLGLIASQMPFFPDVQLDPELFLVLFIAPLLYLEAHEINKSQLLKSLKLSLSLAIGLAIFTMVVVGFSLHTLWPMFPLAAALALGAALGPTDAVAVSSLSHEATLTQRQIGVLKGESLFNDASGIVGFQFAIAAAVTGQFRVGEAAWEFLITFFGGAVFGCIVGVLANWVFESSRQLGWETTTTRILMELFLPFLLYLGAEAVHVSGILSVVAAGLVIRFDRTGIGPNVARTNIVASSVWSVLSFSLNGAVFILLGMLLPGAMRASWDNPMVSNYTLLAVILCVSTLIVGLRFLWVSGMLRLARAQDSHKRRRMTPERWRSAAVMTFGGAKGTITLSLMFTIPYTIADGEWFPMRDELIFIAGGVIIVTLLLSNFLLPVIAPNKAKDVPRETTEASIEVLRRTVEELAELTTDENRSAVMVVINSYTQRIGRLKNQLGTIDPSARIELQIDALNWEKEYVKRKLAEFRLDPTLSEREREVNVEACERLLDQIMDTLRHTNTKHDSSHVVWQVKGRAHLAQRRLVLLSRRAANTIRRSTPLVNENEIYASLRNLELGAFDHVIDRLYEEMSSNTYGTEYVSSLLMDYRRAEAALKSRPNMANSASLVTQIEDVKRESFGIELSVIQNMVEAGDITRAQARQLRKNVYVMSVAADSNF
>NC_012814.1|WP_004218971.1|1898112_1898622_-|nucleoside-deaminase
MRAGGRWHAYKGRGGIAMTQYAEAMGEALAQARMARSAGDVPVGAVVLDAHGEVIGRGRNLRERDADPLAHAEIVAMREAAAVRGNWNLADCTLVVTLEPCPMCAGACLQTRIGRIVFGGWDAKLGACGSVWDIPRDPHVGHEPEVYGGVCERECTALLAEFFHSRRHA
>NC_012814.1|WP_004218969.1|1895774_1897997_-|alpha-galactosidase
MTRISEFNATTHAGEALHVVSMENHDADSAFALAFVADELPRVVHWGRPLTQPRTLVSAVDALRPQRVSGALDETTWPSVLPTQAEAWTGEPRFVVRRDGVELFCRFVVTDIAVGDAGVAVTASDAEQGVEIIWTCEMRDSGLVRQRADVRNLGAGSLEIGKVELGFPVPADMTELLTTTGHHLRERSPQRQPLTIGRFQKASMVGRPDFDASLLLNAGRPGFGFTHGDVYAVHVAWSGNSLMAAERLPYTTGVIGGAEVLAGGEITLHDAADSYTTPWLYGSFGEGLNEVAARFHADLRATHARWRAEHGIADKPRPVILNTWEAVYFEHDYDTLVRLADKAAASGVERFVVDDGWFGDRRGDTAGLGDWRISQDVWPDGEHSLKALADYVHAKGMEFGLWFEPEMVNPDSAMYREHSDWVLMPTAHRLPMQGRNQQVVDLTNPQAYAYVYGCMDSLVGELGIDYIKWDHNKYVTEAVSPRTGSCAVHGQTLAVYRMFHDLKTSHPGLEIESCSSGGGRVDMGILELADRIWASDCVDPVERADIQRYTSLLVPPEMIGEHVGASPAHSTHRATSQEMRMAMAFFGHLGIEWNLLKEPQHDLDLLGEWVHAYKEHRVDFEHGVAVHDDAADPTVRVDGVISADGARAVYRFTQLTTSQTYPAAPIALPGLDAQATYRVRPLALNMASGEPFGEIGNGQSELGWWNANGVEMTGEALASYGLRPPSIHPANAVLFSVTRV
>NC_012814.1|WP_004218985.1|1911957_1912980_+|potassium-channel-family-protein
MTARKSARRPGLTLHTWQHYTNAPMFVLSAFFLFAYSWQILAGTHTRLCNLVINLVWVLYSIDYAISLYLAPNRWSWFKSNLILLITMILPMFQPLRLLRFVPMLHMFNRSAGTASRGRISLYAVAVVAMLIYVGALAEYSVEHKAPGATITSFPLSIWWAFVTVTTVGYGDVYPVTTLGRFIAIILMITGIAVIGIVSAMISSWVIDQVNVRPHPVIPAPAVGEDGGASPSANASTHDAGGCPDEDYTTGDEDIIDAPDPLNGSSLGPSLNPAQSRIVQAELLRLTDSVNRLHNEIEQLRRAEHRHMQASGQTARKLRWHANRNGHMPPHDSPEGDKPA
>NC_012814.1|WP_004218986.1|1913049_1915167_+|protein-kinase
MTDVYALQLQPGDVVGGYTLESRLGSGAMGSVWRAVDGGGNAYAMKILRASLSDSDDGNPDSPEYRAQMVARERLRREAVAMRKIRNSGVCQIVDMEIDDSLAFLVTELIEGENLREDVRHNGKYVGDDLERLSSKLIDAVHAVHEAGIVHRDIKPTNVMISVTGPVLVDFGIAMTPGESHVTSTGLVMGTPGFIAPEVIEGAESTAASDWWSLASVLAFAATGEPVFGTSPMMAVLQREASGHANLAGLPPHTLEAFRAALDPDPAQRCTPQELLEAIRTDAWTSDGEAMLPFDLRRIGRRETDAPGVSGSVLSTHERVENPRTLWHRQSLPTEAMPVNASTGTVPLPPMAQASHAANDNGDIVTPSFNDAESTGGTRVLPQQSFPRKWDSEHTATMPRPQPTTPLAATPPLEAATQSMRPMQSATGFQPVGPEANNAGASPNLDQPQYDAPNGAYAPQAPALPSDYGPVATAYQNTVRMHRTRGILPVLLATLPLMALAAACPMGAGIAASMLIWVELTLGMNLNTHVAHVLRRNGQEGSGSKVLRVAQLPWHAFAALFMSLWSLLLFWAIYVALMLAAIYLVRLPGAYYTLPPEPPWSRLDSVLLLAGSPTGINGLWLAISAAIAWAVTQFGPYSANLRAGAGVIVGLSPKQRLALRPDGNHRNIRRFIVLGIWVIMLALTIFNLEATPSIDWWPILPWSGF
>NC_012814.1|WP_004218987.1|1915546_1916584_+|hypothetical-protein
MAANSKQPKRESRAQRRQEEQARVQAKRERLQKERRTQTIIGIVVTVVLIALIAIAGIAVYRNTHPSAARQQEAANEQSAAQATLKDSKVKPAKASELGGLLMSKNGYNKPVEGVPTVGIYMDFMCPGCGNLNRNLDQDLVKMMDAGQINIDLHIMSFMDRYSWINGDSNNVDDYSSRTANAAIYVAEHDDDPNHLLNFITNLYAKDFQPEEGSGYKQVTDDQIKVRMDGTGISKDVQGKAMQRGYDKWLDAVNTYTPTRSELFNRSGQLKGSMSTPTMTINGYYWDMNSSEVTSHKTLAEAFLEAIGLAQNKVGDAEVRPSIGATGKPLIGYADDNAGAATNSQ
>NC_012814.1|WP_004218988.1|1917251_1918799_+|G5-domain-containing-protein
MARRWTPQRMMRLRTIRIASSMVTIVALLLGFFVCTRKTVALEVNGKTTTVTTFATTIPGFLREQHVKLKTHDLVRSSTPGQLTDNSTVTVQSAYQTTISIDGQQMPFWTVADSAEQLIAFFEQNEVAANRITVDIKNVYNQLTGGLVINADGPVTVIADGKTFIAPNGKLPAASILDSKGITLGKNDRVSVSKDGSQTILRVERVTTKEITETEDVPFSTQTIVDDSLEPGATEVRQEGRNGQNQLRYRVTYVDGKEDSRELLDTTPLSTPIDRIIAIGPEPVKETPQKEDNSGASNDEGQSADQSAGNSAGTNDKQSATENNTGDAAEPSAESSPTPSAQPSQQPGAKPSEQPTSKPTQSAQPTQKPSEQPTQQPSAQPTQQPKPTPTPTQKPTQQPEQPTPSNCRLCKPSPSAAQAYAAGAAAQYGWTGKNWEDLVKLWNRESSWLWYAENKSSGAYGIPQSLPGSKMAQFGENWKEDAAVQIDWGLNYIATHPKYGSPSKAWAHSEKYGWY
>NC_012814.1|WP_004218989.1|1918940_1919834_+|16S-rRNA-(adenine(1518)-N(6)/adenine(1519)-N(6))--dimethyltransferase-RsmA
MGTAQADGGNLLGAADIRRIAAEEGITPTKKFGQNFVIDPGTVRKIVREAGVDAGDQVMEVGPGLGSLTLAILETGADLTAVEIDPPLAQRLPQTIAEFMPNATNRFRVVNMDALKVTPSQLPQLADAATFTLVANLPYNVATPILLTLLERFGNLDSFLVMVQKEVAERLSAQPGSKVYGTPSVKLAWYGTAKSVGNIGRNVFWPAPNVDSALVRFERHAADDPRNPNNRSVGRDLVFRLIDASFAQRRKTLHAALRKIVPSGAFERAGIDPTRRGETLDIDEFVALATACKELEA
>NC_012814.1|WP_004218990.1|1919830_1920787_+|4-diphosphocytidyl-2C-methyl-D-erythritol-kinase
MSAPNGARFQTPTLRADYASVHVDCPAKTNLTLHVGERREEWGGRHALETIYCGVGIYDTVTVTAKEPGTGFSLDLAGTHLGDLAASTSDMRRNHAVLAMFAMAQASGHEPDVSISIEKRIPVAAGLGGGSADAAGTLLALNALWNLNWPVARLREIAAALGADMPFCVTGGLALGTGFGERIKDLTASDPRIEHAVGDLFADAPSGDGVHMLVGAYLSQLSTPEVYSTFDVLGAGEGDLNELQHAAVSLHPRSGVAIREAQQAGATSAFVSGSGPTVIAVVPDDRVREATRAAWQASGAVDRIIDAQAPAAPLMRAE
>NC_012814.1|WP_004218991.1|1920858_1921485_+|LytR-C-terminal-domain-containing-protein
MAENNDAREERREYVHRRQTIVFAVVGAVLVVALFISSLFLFHVGGLGEVKTTAEGADHGVVAPCVSPAEDGSKPKYLDSKSVTTRVLNGTKFSGFANAVGRALQNREFVVQSIDNYDNAKVERTTIVFGKNAIPQAYTLAANFPDAQLQMDDRQDKLVDVILGATFQNLTKTDELPKTGSEIPNIEGCKPANDMKDLPKAPEHTSVG
>NC_012814.1|WP_004268865.1|1921614_1923033_-|CCA-tRNA-nucleotidyltransferase
MNFEVWPEAIELGQMFADEGFELALVGGPVRDLLLHRRSHDLDFCSNARPEQFEPILRRFGHDGFWDMGRKFGTLGAMRRRPDGTEVKVEVTTYRSDVYDPDSRKPEVSYGDSLEGDLSRRDFTVNAMALTVPDLEFVDPFGGANDLNKRVLRTPVDPYQSFDDDPLRMMRAVRFVAQLGFSIEPETAEAITRMTDRIEIVSAERVRDELTKLLLSDRPRAGIEALVDSGLADVVLPEIPALRLEIDEHHRHKDVFDHTMIVVDRAVALETGPDGPVPAPDLVLRLAALMHDIGKPKTRRFEPGGKVSFHHHDAVGAKMTRKRLKALRFDHHVVEQVSDLVDLHLRFHGYVDEPWTDAAVRRYVKDAGPLYARLNRLTRADATTQNRRKALMFEHAMDEMEERVAKLKEQEDIDAIRPDLNGDEIMAELGIAPGPLVGKAYRHMLEYRLDNGPVDHDTAVAELHNWYASQAE
>NC_012814.1|WP_004218995.1|1923218_1924223_+|NUDIX-hydrolase
MITPADVARMHANAAVNHALSPDDPDFDPLVPDELMYTSQTTTVHLNTVLDEARAVKAKLGAERIESASTQAAHMPTPADMPSHPTSHEAAQEQSGPSEDTVPNQARGTRRIPTPAQVAQAAHAARMMQALHATQPLYSSQPVPAQSTAVPAHPMRNAARRDPGKPTPAMMPQRRSTDRRSSFASLDAQELPVVREYSAGGLVFDAHGRVAIIARHSRSGHLEWCLPKGHIEKGETPQQTAVREIHEETGIIGEVVDSIATIDYWFTGTSQRVHKLVHHFALRQTGGELTVEGDPDHEAEDAIWVDFADLDDVLSYPNERKIAWLYARKLNRQA
>NC_012814.1|WP_004218996.1|1924225_1926475_+|hypothetical-protein
MNPHRTDLRHTARQRCKGTALLTVLFTLILALCTGFAVRPAHAEEPDATTNTDQAAKPGVSITVNSMTPVITPSSGYKLNLTVTNNTDADVDHGSIDALTNFTYNFISRTDLQEWAEGRGQIPLPDLLVTLHVPRIAAHKSVTVNSSLPASEEILKQFNSWGPRPLALDYRSDDGAQTSTLHSFVTRSQDGLQGERTPQLHMTMLMPLTAGDWSLDETTLKALRADRSAKTHASAIATLDGKSAEALRTKDQLTQRFPHVQALADPQVLATLQAPHMQALMQPADFDITRYSYADNANGYENAGVPLSSWAASSSVQTLRTVLNDGAAERPVYAMQGVGAWNTEALDTARMQGYDTVIATHDFDDQDDTAAHTGVYRVPTAHGDVTVMATHPMLSQLAAGQATSQEAQAETNTAGRLQRFIAQSAFYQMEQPYQNRCLLVSFGPDSSAANIAAFMGALQEASWLDLTDLETLRASEPYMSGDDAATVADTTTVDPAAYDTTTLDTTLTTLAHTRRDLQHFNTSVLLADGSMPGGPAAQTGDANNTKPGDGDANDADDASDNATSDTSGDALGALQWSNRWLQAHDELALLSLNANTARSSALTAATQAMVDYLRQGIGLTTPTNVNVVSESASLPVTVTNSLPYPISLRISSRTDSMEIVTSRFVDVNVPPGSEAQATLEIRVSTAGTTVANQELVNHEGVPLSGIHTTTITSSLQISDKSGIVFIIIAVLLGIVGLWRQFHRKKDPDE

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Self-targeting detection

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_ID	Protospacer_location	Mismatch	Identity

MGE targeting detection<

CRISPR_ID	Spacer_Info	Spacer_region	Spacer_length	Hit_phage_ID	Hit_phage_def	Protospacer_location	Mismatch	Identity
NC_012814_1	1.7\|183798\|28\|NC_012814\|CRISPRCasFinder	183798-183825	28	NZ_CP042628	Escherichia coli strain NCYU-25-82 plasmid pNCYU-25-82-1_MCR3, complete sequence	11972-11999	5	0.821
NC_012814_1	1.7\|183798\|28\|NC_012814\|CRISPRCasFinder	183798-183825	28	NZ_CP053739	Escherichia coli strain CP8-3_Sichuan plasmid pCP8-3-IncR, complete sequence	4124-4151	5	0.821
NC_012814_1	1.7\|183798\|28\|NC_012814\|CRISPRCasFinder	183798-183825	28	NZ_CP053721	Escherichia coli strain CP131_Sichuan plasmid pCP131-IncHI1, complete sequence	93964-93991	5	0.821
NC_012814_1	1.7\|183798\|28\|NC_012814\|CRISPRCasFinder	183798-183825	28	CP042642	Escherichia coli strain NCYU-24-74 plasmid pNCYU-24-74-4_MCR3, complete sequence	11974-12001	5	0.821
NC_012814_1	1.7\|183798\|28\|NC_012814\|CRISPRCasFinder	183798-183825	28	LC549805	Escherichia coli VNCEc117 plasmid pVNCEc117 DNA, complete sequence	24862-24889	5	0.821
NC_012814_1	1.7\|183798\|28\|NC_012814\|CRISPRCasFinder	183798-183825	28	NZ_CP042618	Escherichia coli strain NCYU-26-73 plasmid pNCYU-26-73-3_MCR3, complete sequence	120679-120706	5	0.821
NC_012814_1	1.7\|183798\|28\|NC_012814\|CRISPRCasFinder	183798-183825	28	NZ_CP041114	Escherichia coli strain ECCTRSRTH03 plasmid unnamed4, complete sequence	26292-26319	5	0.821
NC_012814_1	1.7\|183798\|28\|NC_012814\|CRISPRCasFinder	183798-183825	28	NZ_CP033094	Escherichia coli strain CP53 plasmid pCP53-mcr, complete sequence	76080-76107	5	0.821
NC_012814_1	1.7\|183798\|28\|NC_012814\|CRISPRCasFinder	183798-183825	28	NZ_CP035200	Klebsiella pneumoniae strain LH375 plasmid pLH375-3, complete sequence	38316-38343	5	0.821
NC_012814_1	1.7\|183798\|28\|NC_012814\|CRISPRCasFinder	183798-183825	28	NZ_CP035208	Klebsiella quasipneumoniae strain TH114 plasmid pTH114-3, complete sequence	57753-57780	5	0.821
NC_012814_1	1.7\|183798\|28\|NC_012814\|CRISPRCasFinder	183798-183825	28	NZ_CP035213	Klebsiella pneumoniae strain TH164 plasmid pTH164-3, complete sequence	62999-63026	5	0.821
NC_012814_1	1.7\|183798\|28\|NC_012814\|CRISPRCasFinder	183798-183825	28	NZ_CP035195	Klebsiella pneumoniae strain LH102-A plasmid pLH102-A, complete sequence	580-607	5	0.821
NC_012814_1	1.7\|183798\|28\|NC_012814\|CRISPRCasFinder	183798-183825	28	MH114596	Salmonella enterica strain 13-1681 plasmid p131681, complete sequence	94181-94208	5	0.821
NC_012814_1	1.7\|183798\|28\|NC_012814\|CRISPRCasFinder	183798-183825	28	NZ_CP050727	Salmonella enterica subsp. enterica serovar Typhimurium strain ST113 plasmid pST-1, complete sequence	96797-96824	5	0.821
NC_012814_1	1.7\|183798\|28\|NC_012814\|CRISPRCasFinder	183798-183825	28	NZ_MK656937	Escherichia coli strain T3 plasmid pT3, complete sequence	66543-66570	5	0.821
NC_012814_1	1.7\|183798\|28\|NC_012814\|CRISPRCasFinder	183798-183825	28	NZ_MH341574	Klebsiella pneumoniae strain MYKLB95 plasmid MYKLB95-1, complete sequence	63574-63601	5	0.821
NC_012814_1	1.7\|183798\|28\|NC_012814\|CRISPRCasFinder	183798-183825	28	NZ_MF678351	Escherichia coli strain WCHEC025943 plasmid pMCR3_WCHEC1943, complete sequence	11573-11600	5	0.821
NC_012814_1	1.7\|183798\|28\|NC_012814\|CRISPRCasFinder	183798-183825	28	NZ_CP035205	Klebsiella pneumoniae strain LH94 plasmid pLH94-3, complete sequence	56399-56426	5	0.821
NC_012814_1	1.7\|183798\|28\|NC_012814\|CRISPRCasFinder	183798-183825	28	NZ_KX377410	Klebsiella pneumoniae strain WCHKP1511 plasmid pMCR_1511, complete sequence	54987-55014	5	0.821
NC_012814_1	1.7\|183798\|28\|NC_012814\|CRISPRCasFinder	183798-183825	28	MG780294	Escherichia coli plasmid pHN8, complete sequence	16608-16635	5	0.821
NC_012814_1	1.7\|183798\|28\|NC_012814\|CRISPRCasFinder	183798-183825	28	NZ_CP042602	Escherichia coli strain NCYU-29-69 plasmid pNCYU-29-69-3_MCR3, complete sequence	23677-23704	5	0.821
NC_012814_1	1.7\|183798\|28\|NC_012814\|CRISPRCasFinder	183798-183825	28	NZ_CP053734	Escherichia coli strain CP55_Sichuan plasmid pCP55-IncFII, complete sequence	7728-7755	5	0.821
NC_012814_1	1.7\|183798\|28\|NC_012814\|CRISPRCasFinder	183798-183825	28	NZ_CP053729	Escherichia coli strain CP61_Sichuan plasmid pCP61-IncFIB, complete sequence	62482-62509	5	0.821
NC_012814_1	1.7\|183798\|28\|NC_012814\|CRISPRCasFinder	183798-183825	28	NZ_CP053725	Escherichia coli strain CP66-6_Sichuan plasmid pCP66-6-IncFII, complete sequence	28939-28966	5	0.821
NC_012814_1	1.7\|183798\|28\|NC_012814\|CRISPRCasFinder	183798-183825	28	LC549806	Escherichia coli VNCEc57 plasmid pVNCEc57 DNA, complete sequence	5619-5646	5	0.821
NC_012814_1	1.7\|183798\|28\|NC_012814\|CRISPRCasFinder	183798-183825	28	NZ_CP039562	Salmonella enterica subsp. enterica serovar 1,4,[5],12:i:- strain PNCS014847 plasmid p08-5333.1, complete sequence	168070-168097	5	0.821
NC_012814_1	1.7\|183798\|28\|NC_012814\|CRISPRCasFinder	183798-183825	28	NZ_CP041095	Klebsiella pneumoniae subsp. pneumoniae strain KPCTRSRTH01 plasmid unnamed3, complete sequence	65966-65993	5	0.821
NC_012814_1	1.7\|183798\|28\|NC_012814\|CRISPRCasFinder	183798-183825	28	NZ_CP041104	Klebsiella pneumoniae subsp. pneumoniae strain KPCTRSRTH07 plasmid unnamed5, complete sequence	19874-19901	5	0.821
NC_012814_1	1.7\|183798\|28\|NC_012814\|CRISPRCasFinder	183798-183825	28	NZ_CP042608	Escherichia coli strain NCYU-29-19 plasmid pNCYU-29-19-2_MCR3, complete sequence	4476-4503	5	0.821
NC_012814_1	1.7\|183798\|28\|NC_012814\|CRISPRCasFinder	183798-183825	28	AP018353	Escherichia coli plasmid pVE769 DNA, complete genome, strain: E769	8379-8406	5	0.821
NC_012814_1	1.7\|183798\|28\|NC_012814\|CRISPRCasFinder	183798-183825	28	AP018354	Escherichia coli plasmid pVE155 DNA, complete genome, strain: E155	9181-9208	5	0.821
NC_012814_1	1.7\|183798\|28\|NC_012814\|CRISPRCasFinder	183798-183825	28	NZ_CP050732	Salmonella enterica subsp. enterica serovar Typhimurium strain ST101 plasmid pST101-1, complete sequence	81157-81184	5	0.821
NC_012814_1	1.7\|183798\|28\|NC_012814\|CRISPRCasFinder	183798-183825	28	NZ_CP045953	Salmonella enterica subsp. enterica serovar Typhimurium strain AUSMDU00008979 plasmid pAUSMDU00008979_01, complete sequence	84530-84557	5	0.821
NC_012814_1	1.7\|183798\|28\|NC_012814\|CRISPRCasFinder	183798-183825	28	NZ_MK770642	Klebsiella pneumoniae strain T38 plasmid pT38_MCR3, complete sequence	104267-104294	5	0.821
NC_012814_1	1.7\|183798\|28\|NC_012814\|CRISPRCasFinder	183798-183825	28	NZ_AP018939	Escherichia coli strain JSWP006 plasmid pJSWP006_1, complete sequence	78720-78747	5	0.821
NC_012814_1	1.7\|183798\|28\|NC_012814\|CRISPRCasFinder	183798-183825	28	NZ_MH043623	Escherichia coli strain GDZJ002 plasmid pGDZJ002-1, complete sequence	49606-49633	5	0.821
NC_012814_1	1.7\|183798\|28\|NC_012814\|CRISPRCasFinder	183798-183825	28	NZ_MH043626	Escherichia coli strain GDZJ004 plasmid pGDZJ004, complete sequence	49219-49246	5	0.821
NC_012814_1	1.7\|183798\|28\|NC_012814\|CRISPRCasFinder	183798-183825	28	NZ_MG552133	Escherichia coli strain ECSC102 plasmid pECSC102, complete sequence	48730-48757	5	0.821
NC_012814_1	1.7\|183798\|28\|NC_012814\|CRISPRCasFinder	183798-183825	28	NZ_MF489760	Escherichia coli strain WCHEC-LL123 plasmid pMCR3_WCHEC-LL123, complete sequence	50908-50935	5	0.821
NC_012814_1	1.7\|183798\|28\|NC_012814\|CRISPRCasFinder	183798-183825	28	NZ_MH077952	Escherichia coli strain EC17S-208 plasmid p17S-208, complete sequence	23294-23321	5	0.821
NC_012814_1	1.7\|183798\|28\|NC_012814\|CRISPRCasFinder	183798-183825	28	NZ_MH043625	Escherichia coli strain GDZJ003 plasmid pGDZJ003-1-MCR-3, complete sequence	49236-49263	5	0.821
NC_012814_1	1.7\|183798\|28\|NC_012814\|CRISPRCasFinder	183798-183825	28	NZ_CP027203	Escherichia coli strain WCHEC025943 plasmid pMCR3_025943, complete sequence	36962-36989	5	0.821
NC_012814_1	1.6\|183746\|29\|NC_012814\|CRISPRCasFinder	183746-183774	29	NZ_CP023068	Ensifer sojae CCBAU 05684 plasmid pSJ05684b, complete sequence	1640519-1640547	6	0.793
NC_012814_1	1.6\|183746\|29\|NC_012814\|CRISPRCasFinder	183746-183774	29	MH067974	Arthrobacter sp. strain ANT_H58 plasmid pA58H1, complete sequence	31125-31153	6	0.793
NC_012814_1	1.5\|183694\|29\|NC_012814\|CRISPRCasFinder	183694-183722	29	NZ_CP018233	Rhizobium leguminosarum strain Vaf-108 plasmid unnamed5, complete sequence	133734-133762	7	0.759
NC_012814_1	1.5\|183694\|29\|NC_012814\|CRISPRCasFinder	183694-183722	29	NZ_CP016293	Rhizobium leguminosarum strain Vaf10 plasmid unnamed5, complete sequence	235632-235660	7	0.759
NC_012814_1	1.5\|183694\|29\|NC_012814\|CRISPRCasFinder	183694-183722	29	NZ_CP022569	Rhizobium leguminosarum bv. viciae strain BIHB 1148 plasmid pSK05, complete sequence	149169-149197	7	0.759
NC_012814_4	4.16\|1512731\|34\|NC_012814\|CRISPRCasFinder,CRT	1512731-1512764	34	NZ_CP031601	Roseovarius indicus strain DSM 26383 plasmid pRIdsm_03, complete sequence	33620-33653	7	0.794
NC_012814_4	4.38\|1512732\|34\|NC_012814\|PILER-CR	1512732-1512765	34	NZ_CP031601	Roseovarius indicus strain DSM 26383 plasmid pRIdsm_03, complete sequence	33620-33653	7	0.794
NC_012814_1	1.6\|183746\|29\|NC_012814\|CRISPRCasFinder	183746-183774	29	NC_007950	Polaromonas sp. JS666 plasmid 2, complete sequence	275288-275316	8	0.724
NC_012814_4	4.1\|1511651\|35\|NC_012814\|CRISPRCasFinder,CRT	1511651-1511685	35	MH001451	Mycobacterium phage Nairb, complete genome	7175-7209	8	0.771
NC_012814_4	4.1\|1511651\|35\|NC_012814\|CRISPRCasFinder,CRT	1511651-1511685	35	MF155936	Mycobacterium phage ZenTime222, complete genome	7175-7209	8	0.771
NC_012814_4	4.1\|1511651\|35\|NC_012814\|CRISPRCasFinder,CRT	1511651-1511685	35	MK494089	Mycobacterium phage Ibrahim, complete genome	7175-7209	8	0.771
NC_012814_4	4.1\|1511651\|35\|NC_012814\|CRISPRCasFinder,CRT	1511651-1511685	35	NC_024135	Mycobacterium phage Bernal13, complete genome	7175-7209	8	0.771
NC_012814_4	4.1\|1511651\|35\|NC_012814\|CRISPRCasFinder,CRT	1511651-1511685	35	MG925349	Mycobacterium phage Mendokysei, complete genome	7107-7141	8	0.771
NC_012814_4	4.1\|1511651\|35\|NC_012814\|CRISPRCasFinder,CRT	1511651-1511685	35	KM591905	Mycobacterium phage RonRayGun, complete genome	7175-7209	8	0.771
NC_012814_4	4.1\|1511651\|35\|NC_012814\|CRISPRCasFinder,CRT	1511651-1511685	35	MN735432	Mycobacteriophage Whitty, complete genome	7175-7209	8	0.771
NC_012814_4	4.16\|1512731\|34\|NC_012814\|CRISPRCasFinder,CRT	1512731-1512764	34	NZ_CP045383	Labrenzia sp. THAF35 plasmid pTHAF35_c, complete sequence	15510-15543	8	0.765
NC_012814_4	4.23\|1511652\|35\|NC_012814\|PILER-CR	1511652-1511686	35	MH001451	Mycobacterium phage Nairb, complete genome	7175-7209	8	0.771
NC_012814_4	4.23\|1511652\|35\|NC_012814\|PILER-CR	1511652-1511686	35	MF155936	Mycobacterium phage ZenTime222, complete genome	7175-7209	8	0.771
NC_012814_4	4.23\|1511652\|35\|NC_012814\|PILER-CR	1511652-1511686	35	MK494089	Mycobacterium phage Ibrahim, complete genome	7175-7209	8	0.771
NC_012814_4	4.23\|1511652\|35\|NC_012814\|PILER-CR	1511652-1511686	35	NC_024135	Mycobacterium phage Bernal13, complete genome	7175-7209	8	0.771
NC_012814_4	4.23\|1511652\|35\|NC_012814\|PILER-CR	1511652-1511686	35	MG925349	Mycobacterium phage Mendokysei, complete genome	7107-7141	8	0.771
NC_012814_4	4.23\|1511652\|35\|NC_012814\|PILER-CR	1511652-1511686	35	KM591905	Mycobacterium phage RonRayGun, complete genome	7175-7209	8	0.771
NC_012814_4	4.23\|1511652\|35\|NC_012814\|PILER-CR	1511652-1511686	35	MN735432	Mycobacteriophage Whitty, complete genome	7175-7209	8	0.771
NC_012814_4	4.38\|1512732\|34\|NC_012814\|PILER-CR	1512732-1512765	34	NZ_CP045383	Labrenzia sp. THAF35 plasmid pTHAF35_c, complete sequence	15510-15543	8	0.765
NC_012814_5	5.1\|1911875\|33\|NC_012814\|CRISPRCasFinder	1911875-1911907	33	MT939492	Xanthomonas phage Xoo-sp14, complete genome	18873-18905	8	0.758

1. spacer 1.7|183798|28|NC_012814|CRISPRCasFinder matches to NZ_CP042628 (Escherichia coli strain NCYU-25-82 plasmid pNCYU-25-82-1_MCR3, complete sequence) position: , mismatch: 5, identity: 0.821

taggctgtgccattttagattcctttgt	CRISPR spacer
caggctttgccattttagcttcctcttt	Protospacer
.***** *********** *****.* *

2. spacer 1.7|183798|28|NC_012814|CRISPRCasFinder matches to NZ_CP053739 (Escherichia coli strain CP8-3_Sichuan plasmid pCP8-3-IncR, complete sequence) position: , mismatch: 5, identity: 0.821

taggctgtgccattttagattcctttgt	CRISPR spacer
caggctttgccattttagcttcctcttt	Protospacer
.***** *********** *****.* *

3. spacer 1.7|183798|28|NC_012814|CRISPRCasFinder matches to NZ_CP053721 (Escherichia coli strain CP131_Sichuan plasmid pCP131-IncHI1, complete sequence) position: , mismatch: 5, identity: 0.821

taggctgtgccattttagattcctttgt	CRISPR spacer
caggctttgccattttagcttcctcttt	Protospacer
.***** *********** *****.* *

4. spacer 1.7|183798|28|NC_012814|CRISPRCasFinder matches to CP042642 (Escherichia coli strain NCYU-24-74 plasmid pNCYU-24-74-4_MCR3, complete sequence) position: , mismatch: 5, identity: 0.821

taggctgtgccattttagattcctttgt	CRISPR spacer
caggctttgccattttagcttcctcttt	Protospacer
.***** *********** *****.* *

5. spacer 1.7|183798|28|NC_012814|CRISPRCasFinder matches to LC549805 (Escherichia coli VNCEc117 plasmid pVNCEc117 DNA, complete sequence) position: , mismatch: 5, identity: 0.821

taggctgtgccattttagattcctttgt	CRISPR spacer
caggctttgccattttagcttcctcttt	Protospacer
.***** *********** *****.* *

6. spacer 1.7|183798|28|NC_012814|CRISPRCasFinder matches to NZ_CP042618 (Escherichia coli strain NCYU-26-73 plasmid pNCYU-26-73-3_MCR3, complete sequence) position: , mismatch: 5, identity: 0.821

taggctgtgccattttagattcctttgt	CRISPR spacer
caggctttgccattttagcttcctcttt	Protospacer
.***** *********** *****.* *

7. spacer 1.7|183798|28|NC_012814|CRISPRCasFinder matches to NZ_CP041114 (Escherichia coli strain ECCTRSRTH03 plasmid unnamed4, complete sequence) position: , mismatch: 5, identity: 0.821

taggctgtgccattttagattcctttgt	CRISPR spacer
caggctttgccattttagcttcctcttt	Protospacer
.***** *********** *****.* *

8. spacer 1.7|183798|28|NC_012814|CRISPRCasFinder matches to NZ_CP033094 (Escherichia coli strain CP53 plasmid pCP53-mcr, complete sequence) position: , mismatch: 5, identity: 0.821

taggctgtgccattttagattcctttgt	CRISPR spacer
caggctttgccattttagcttcctcttt	Protospacer
.***** *********** *****.* *

9. spacer 1.7|183798|28|NC_012814|CRISPRCasFinder matches to NZ_CP035200 (Klebsiella pneumoniae strain LH375 plasmid pLH375-3, complete sequence) position: , mismatch: 5, identity: 0.821

taggctgtgccattttagattcctttgt	CRISPR spacer
caggctttgccattttagcttcctcttt	Protospacer
.***** *********** *****.* *

10. spacer 1.7|183798|28|NC_012814|CRISPRCasFinder matches to NZ_CP035208 (Klebsiella quasipneumoniae strain TH114 plasmid pTH114-3, complete sequence) position: , mismatch: 5, identity: 0.821

taggctgtgccattttagattcctttgt	CRISPR spacer
caggctttgccattttagcttcctcttt	Protospacer
.***** *********** *****.* *

11. spacer 1.7|183798|28|NC_012814|CRISPRCasFinder matches to NZ_CP035213 (Klebsiella pneumoniae strain TH164 plasmid pTH164-3, complete sequence) position: , mismatch: 5, identity: 0.821

taggctgtgccattttagattcctttgt	CRISPR spacer
caggctttgccattttagcttcctcttt	Protospacer
.***** *********** *****.* *

12. spacer 1.7|183798|28|NC_012814|CRISPRCasFinder matches to NZ_CP035195 (Klebsiella pneumoniae strain LH102-A plasmid pLH102-A, complete sequence) position: , mismatch: 5, identity: 0.821

taggctgtgccattttagattcctttgt	CRISPR spacer
caggctttgccattttagcttcctcttt	Protospacer
.***** *********** *****.* *

13. spacer 1.7|183798|28|NC_012814|CRISPRCasFinder matches to MH114596 (Salmonella enterica strain 13-1681 plasmid p131681, complete sequence) position: , mismatch: 5, identity: 0.821

taggctgtgccattttagattcctttgt	CRISPR spacer
caggctttgccattttagcttcctcttt	Protospacer
.***** *********** *****.* *

14. spacer 1.7|183798|28|NC_012814|CRISPRCasFinder matches to NZ_CP050727 (Salmonella enterica subsp. enterica serovar Typhimurium strain ST113 plasmid pST-1, complete sequence) position: , mismatch: 5, identity: 0.821

taggctgtgccattttagattcctttgt	CRISPR spacer
caggctttgccattttagcttcctcttt	Protospacer
.***** *********** *****.* *

15. spacer 1.7|183798|28|NC_012814|CRISPRCasFinder matches to NZ_MK656937 (Escherichia coli strain T3 plasmid pT3, complete sequence) position: , mismatch: 5, identity: 0.821

taggctgtgccattttagattcctttgt	CRISPR spacer
caggctttgccattttagcttcctcttt	Protospacer
.***** *********** *****.* *

16. spacer 1.7|183798|28|NC_012814|CRISPRCasFinder matches to NZ_MH341574 (Klebsiella pneumoniae strain MYKLB95 plasmid MYKLB95-1, complete sequence) position: , mismatch: 5, identity: 0.821

taggctgtgccattttagattcctttgt	CRISPR spacer
caggctttgccattttagcttcctcttt	Protospacer
.***** *********** *****.* *

17. spacer 1.7|183798|28|NC_012814|CRISPRCasFinder matches to NZ_MF678351 (Escherichia coli strain WCHEC025943 plasmid pMCR3_WCHEC1943, complete sequence) position: , mismatch: 5, identity: 0.821

taggctgtgccattttagattcctttgt	CRISPR spacer
caggctttgccattttagcttcctcttt	Protospacer
.***** *********** *****.* *

18. spacer 1.7|183798|28|NC_012814|CRISPRCasFinder matches to NZ_CP035205 (Klebsiella pneumoniae strain LH94 plasmid pLH94-3, complete sequence) position: , mismatch: 5, identity: 0.821

taggctgtgccattttagattcctttgt	CRISPR spacer
caggctttgccattttagcttcctcttt	Protospacer
.***** *********** *****.* *

19. spacer 1.7|183798|28|NC_012814|CRISPRCasFinder matches to NZ_KX377410 (Klebsiella pneumoniae strain WCHKP1511 plasmid pMCR_1511, complete sequence) position: , mismatch: 5, identity: 0.821

taggctgtgccattttagattcctttgt	CRISPR spacer
caggctttgccattttagcttcctcttt	Protospacer
.***** *********** *****.* *

20. spacer 1.7|183798|28|NC_012814|CRISPRCasFinder matches to MG780294 (Escherichia coli plasmid pHN8, complete sequence) position: , mismatch: 5, identity: 0.821

taggctgtgccattttagattcctttgt	CRISPR spacer
caggctttgccattttagcttcctcttt	Protospacer
.***** *********** *****.* *

21. spacer 1.7|183798|28|NC_012814|CRISPRCasFinder matches to NZ_CP042602 (Escherichia coli strain NCYU-29-69 plasmid pNCYU-29-69-3_MCR3, complete sequence) position: , mismatch: 5, identity: 0.821

taggctgtgccattttagattcctttgt	CRISPR spacer
caggctttgccattttagcttcctcttt	Protospacer
.***** *********** *****.* *

22. spacer 1.7|183798|28|NC_012814|CRISPRCasFinder matches to NZ_CP053734 (Escherichia coli strain CP55_Sichuan plasmid pCP55-IncFII, complete sequence) position: , mismatch: 5, identity: 0.821

taggctgtgccattttagattcctttgt	CRISPR spacer
caggctttgccattttagcttcctcttt	Protospacer
.***** *********** *****.* *

23. spacer 1.7|183798|28|NC_012814|CRISPRCasFinder matches to NZ_CP053729 (Escherichia coli strain CP61_Sichuan plasmid pCP61-IncFIB, complete sequence) position: , mismatch: 5, identity: 0.821

taggctgtgccattttagattcctttgt	CRISPR spacer
caggctttgccattttagcttcctcttt	Protospacer
.***** *********** *****.* *

24. spacer 1.7|183798|28|NC_012814|CRISPRCasFinder matches to NZ_CP053725 (Escherichia coli strain CP66-6_Sichuan plasmid pCP66-6-IncFII, complete sequence) position: , mismatch: 5, identity: 0.821

taggctgtgccattttagattcctttgt	CRISPR spacer
caggctttgccattttagcttcctcttt	Protospacer
.***** *********** *****.* *

25. spacer 1.7|183798|28|NC_012814|CRISPRCasFinder matches to LC549806 (Escherichia coli VNCEc57 plasmid pVNCEc57 DNA, complete sequence) position: , mismatch: 5, identity: 0.821

taggctgtgccattttagattcctttgt	CRISPR spacer
caggctttgccattttagcttcctcttt	Protospacer
.***** *********** *****.* *

26. spacer 1.7|183798|28|NC_012814|CRISPRCasFinder matches to NZ_CP039562 (Salmonella enterica subsp. enterica serovar 1,4,[5],12:i:- strain PNCS014847 plasmid p08-5333.1, complete sequence) position: , mismatch: 5, identity: 0.821

taggctgtgccattttagattcctttgt	CRISPR spacer
caggctttgccattttagcttcctcttt	Protospacer
.***** *********** *****.* *

27. spacer 1.7|183798|28|NC_012814|CRISPRCasFinder matches to NZ_CP041095 (Klebsiella pneumoniae subsp. pneumoniae strain KPCTRSRTH01 plasmid unnamed3, complete sequence) position: , mismatch: 5, identity: 0.821

taggctgtgccattttagattcctttgt	CRISPR spacer
caggctttgccattttagcttcctcttt	Protospacer
.***** *********** *****.* *

28. spacer 1.7|183798|28|NC_012814|CRISPRCasFinder matches to NZ_CP041104 (Klebsiella pneumoniae subsp. pneumoniae strain KPCTRSRTH07 plasmid unnamed5, complete sequence) position: , mismatch: 5, identity: 0.821

taggctgtgccattttagattcctttgt	CRISPR spacer
caggctttgccattttagcttcctcttt	Protospacer
.***** *********** *****.* *

29. spacer 1.7|183798|28|NC_012814|CRISPRCasFinder matches to NZ_CP042608 (Escherichia coli strain NCYU-29-19 plasmid pNCYU-29-19-2_MCR3, complete sequence) position: , mismatch: 5, identity: 0.821

taggctgtgccattttagattcctttgt	CRISPR spacer
caggctttgccattttagcttcctcttt	Protospacer
.***** *********** *****.* *

30. spacer 1.7|183798|28|NC_012814|CRISPRCasFinder matches to AP018353 (Escherichia coli plasmid pVE769 DNA, complete genome, strain: E769) position: , mismatch: 5, identity: 0.821

taggctgtgccattttagattcctttgt	CRISPR spacer
caggctttgccattttagcttcctcttt	Protospacer
.***** *********** *****.* *

31. spacer 1.7|183798|28|NC_012814|CRISPRCasFinder matches to AP018354 (Escherichia coli plasmid pVE155 DNA, complete genome, strain: E155) position: , mismatch: 5, identity: 0.821

taggctgtgccattttagattcctttgt	CRISPR spacer
caggctttgccattttagcttcctcttt	Protospacer
.***** *********** *****.* *

32. spacer 1.7|183798|28|NC_012814|CRISPRCasFinder matches to NZ_CP050732 (Salmonella enterica subsp. enterica serovar Typhimurium strain ST101 plasmid pST101-1, complete sequence) position: , mismatch: 5, identity: 0.821

taggctgtgccattttagattcctttgt	CRISPR spacer
caggctttgccattttagcttcctcttt	Protospacer
.***** *********** *****.* *

33. spacer 1.7|183798|28|NC_012814|CRISPRCasFinder matches to NZ_CP045953 (Salmonella enterica subsp. enterica serovar Typhimurium strain AUSMDU00008979 plasmid pAUSMDU00008979_01, complete sequence) position: , mismatch: 5, identity: 0.821

taggctgtgccattttagattcctttgt	CRISPR spacer
caggctttgccattttagcttcctcttt	Protospacer
.***** *********** *****.* *

34. spacer 1.7|183798|28|NC_012814|CRISPRCasFinder matches to NZ_MK770642 (Klebsiella pneumoniae strain T38 plasmid pT38_MCR3, complete sequence) position: , mismatch: 5, identity: 0.821

taggctgtgccattttagattcctttgt	CRISPR spacer
caggctttgccattttagcttcctcttt	Protospacer
.***** *********** *****.* *

35. spacer 1.7|183798|28|NC_012814|CRISPRCasFinder matches to NZ_AP018939 (Escherichia coli strain JSWP006 plasmid pJSWP006_1, complete sequence) position: , mismatch: 5, identity: 0.821

taggctgtgccattttagattcctttgt	CRISPR spacer
caggctttgccattttagcttcctcttt	Protospacer
.***** *********** *****.* *

36. spacer 1.7|183798|28|NC_012814|CRISPRCasFinder matches to NZ_MH043623 (Escherichia coli strain GDZJ002 plasmid pGDZJ002-1, complete sequence) position: , mismatch: 5, identity: 0.821

taggctgtgccattttagattcctttgt	CRISPR spacer
caggctttgccattttagcttcctcttt	Protospacer
.***** *********** *****.* *

37. spacer 1.7|183798|28|NC_012814|CRISPRCasFinder matches to NZ_MH043626 (Escherichia coli strain GDZJ004 plasmid pGDZJ004, complete sequence) position: , mismatch: 5, identity: 0.821

taggctgtgccattttagattcctttgt	CRISPR spacer
caggctttgccattttagcttcctcttt	Protospacer
.***** *********** *****.* *

38. spacer 1.7|183798|28|NC_012814|CRISPRCasFinder matches to NZ_MG552133 (Escherichia coli strain ECSC102 plasmid pECSC102, complete sequence) position: , mismatch: 5, identity: 0.821

taggctgtgccattttagattcctttgt	CRISPR spacer
caggctttgccattttagcttcctcttt	Protospacer
.***** *********** *****.* *

39. spacer 1.7|183798|28|NC_012814|CRISPRCasFinder matches to NZ_MF489760 (Escherichia coli strain WCHEC-LL123 plasmid pMCR3_WCHEC-LL123, complete sequence) position: , mismatch: 5, identity: 0.821

taggctgtgccattttagattcctttgt	CRISPR spacer
caggctttgccattttagcttcctcttt	Protospacer
.***** *********** *****.* *

40. spacer 1.7|183798|28|NC_012814|CRISPRCasFinder matches to NZ_MH077952 (Escherichia coli strain EC17S-208 plasmid p17S-208, complete sequence) position: , mismatch: 5, identity: 0.821

taggctgtgccattttagattcctttgt	CRISPR spacer
caggctttgccattttagcttcctcttt	Protospacer
.***** *********** *****.* *

41. spacer 1.7|183798|28|NC_012814|CRISPRCasFinder matches to NZ_MH043625 (Escherichia coli strain GDZJ003 plasmid pGDZJ003-1-MCR-3, complete sequence) position: , mismatch: 5, identity: 0.821

taggctgtgccattttagattcctttgt	CRISPR spacer
caggctttgccattttagcttcctcttt	Protospacer
.***** *********** *****.* *

42. spacer 1.7|183798|28|NC_012814|CRISPRCasFinder matches to NZ_CP027203 (Escherichia coli strain WCHEC025943 plasmid pMCR3_025943, complete sequence) position: , mismatch: 5, identity: 0.821

taggctgtgccattttagattcctttgt	CRISPR spacer
caggctttgccattttagcttcctcttt	Protospacer
.***** *********** *****.* *

43. spacer 1.6|183746|29|NC_012814|CRISPRCasFinder matches to NZ_CP023068 (Ensifer sojae CCBAU 05684 plasmid pSJ05684b, complete sequence) position: , mismatch: 6, identity: 0.793

tatgctgtgccgctgcaggggtggtttgc	CRISPR spacer
cgtgctgtgccgctgcagggatggtgagg	Protospacer
..******************.****  *

44. spacer 1.6|183746|29|NC_012814|CRISPRCasFinder matches to MH067974 (Arthrobacter sp. strain ANT_H58 plasmid pA58H1, complete sequence) position: , mismatch: 6, identity: 0.793

tatgctgtgccgctgcaggggtggtttgc	CRISPR spacer
cctgctgtgctgctgcgggggtggtatcc	Protospacer
. ********.*****.******** * *

45. spacer 1.5|183694|29|NC_012814|CRISPRCasFinder matches to NZ_CP018233 (Rhizobium leguminosarum strain Vaf-108 plasmid unnamed5, complete sequence) position: , mismatch: 7, identity: 0.759

tgagatgtgcctctgatggggtggtttct	CRISPR spacer
cgagatgtgcctcttctggggtggtcagc	Protospacer
.*************  *********.  .

46. spacer 1.5|183694|29|NC_012814|CRISPRCasFinder matches to NZ_CP016293 (Rhizobium leguminosarum strain Vaf10 plasmid unnamed5, complete sequence) position: , mismatch: 7, identity: 0.759

tgagatgtgcctctgatggggtggtttct	CRISPR spacer
cgagatgtgcctcttctggggtggtcagc	Protospacer
.*************  *********.  .

47. spacer 1.5|183694|29|NC_012814|CRISPRCasFinder matches to NZ_CP022569 (Rhizobium leguminosarum bv. viciae strain BIHB 1148 plasmid pSK05, complete sequence) position: , mismatch: 7, identity: 0.759

tgagatgtgcctctgatggggtggtttct	CRISPR spacer
cgagatgtgcctcttctggggtggtcagc	Protospacer
.*************  *********.  .

48. spacer 4.16|1512731|34|NC_012814|CRISPRCasFinder,CRT matches to NZ_CP031601 (Roseovarius indicus strain DSM 26383 plasmid pRIdsm_03, complete sequence) position: , mismatch: 7, identity: 0.794

tcgcaggtgaatatcggtggcggcggcttgtcgt	CRISPR spacer
tcacaggtgaatatcggtggaggcggatgatgga	Protospacer
**.***************** ***** * .* *

49. spacer 4.38|1512732|34|NC_012814|PILER-CR matches to NZ_CP031601 (Roseovarius indicus strain DSM 26383 plasmid pRIdsm_03, complete sequence) position: , mismatch: 7, identity: 0.794

tcgcaggtgaatatcggtggcggcggcttgtcgt	CRISPR spacer
tcacaggtgaatatcggtggaggcggatgatgga	Protospacer
**.***************** ***** * .* *

50. spacer 1.6|183746|29|NC_012814|CRISPRCasFinder matches to NC_007950 (Polaromonas sp. JS666 plasmid 2, complete sequence) position: , mismatch: 8, identity: 0.724

tatgctgtgccgctgcaggggtggtttgc	CRISPR spacer
aaccatgtgccgctgcagggctggttgat	Protospacer
 *.  *************** ***** ..

51. spacer 4.1|1511651|35|NC_012814|CRISPRCasFinder,CRT matches to MH001451 (Mycobacterium phage Nairb, complete genome) position: , mismatch: 8, identity: 0.771

gcctcctgatggatctccacgacgttgctggccct	CRISPR spacer
gattcctggtggatctccaccacgttgctgacggc	Protospacer
* .*****.*********** *********.*  .

52. spacer 4.1|1511651|35|NC_012814|CRISPRCasFinder,CRT matches to MF155936 (Mycobacterium phage ZenTime222, complete genome) position: , mismatch: 8, identity: 0.771

gcctcctgatggatctccacgacgttgctggccct	CRISPR spacer
gattcctggtggatctccaccacgttgctgacggc	Protospacer
* .*****.*********** *********.*  .

53. spacer 4.1|1511651|35|NC_012814|CRISPRCasFinder,CRT matches to MK494089 (Mycobacterium phage Ibrahim, complete genome) position: , mismatch: 8, identity: 0.771

gcctcctgatggatctccacgacgttgctggccct	CRISPR spacer
gattcctggtggatctccaccacgttgctgacggc	Protospacer
* .*****.*********** *********.*  .

54. spacer 4.1|1511651|35|NC_012814|CRISPRCasFinder,CRT matches to NC_024135 (Mycobacterium phage Bernal13, complete genome) position: , mismatch: 8, identity: 0.771

gcctcctgatggatctccacgacgttgctggccct	CRISPR spacer
gattcctggtggatctccaccacgttgctgacggc	Protospacer
* .*****.*********** *********.*  .

55. spacer 4.1|1511651|35|NC_012814|CRISPRCasFinder,CRT matches to MG925349 (Mycobacterium phage Mendokysei, complete genome) position: , mismatch: 8, identity: 0.771

gcctcctgatggatctccacgacgttgctggccct	CRISPR spacer
gattcctggtggatctccaccacgttgctgacggc	Protospacer
* .*****.*********** *********.*  .

56. spacer 4.1|1511651|35|NC_012814|CRISPRCasFinder,CRT matches to KM591905 (Mycobacterium phage RonRayGun, complete genome) position: , mismatch: 8, identity: 0.771

gcctcctgatggatctccacgacgttgctggccct	CRISPR spacer
gattcctggtggatctccaccacgttgctgacggc	Protospacer
* .*****.*********** *********.*  .

57. spacer 4.1|1511651|35|NC_012814|CRISPRCasFinder,CRT matches to MN735432 (Mycobacteriophage Whitty, complete genome) position: , mismatch: 8, identity: 0.771

gcctcctgatggatctccacgacgttgctggccct	CRISPR spacer
gattcctggtggatctccaccacgttgctgacggc	Protospacer
* .*****.*********** *********.*  .

58. spacer 4.16|1512731|34|NC_012814|CRISPRCasFinder,CRT matches to NZ_CP045383 (Labrenzia sp. THAF35 plasmid pTHAF35_c, complete sequence) position: , mismatch: 8, identity: 0.765

tcgcaggtgaatatcggtggcggcggcttgtcgt	CRISPR spacer
tcacaggtgaatatcggtggaggcagatggcgga	Protospacer
**.***************** ***.* * *. *

59. spacer 4.23|1511652|35|NC_012814|PILER-CR matches to MH001451 (Mycobacterium phage Nairb, complete genome) position: , mismatch: 8, identity: 0.771

gcctcctgatggatctccacgacgttgctggccct	CRISPR spacer
gattcctggtggatctccaccacgttgctgacggc	Protospacer
* .*****.*********** *********.*  .

60. spacer 4.23|1511652|35|NC_012814|PILER-CR matches to MF155936 (Mycobacterium phage ZenTime222, complete genome) position: , mismatch: 8, identity: 0.771

gcctcctgatggatctccacgacgttgctggccct	CRISPR spacer
gattcctggtggatctccaccacgttgctgacggc	Protospacer
* .*****.*********** *********.*  .

61. spacer 4.23|1511652|35|NC_012814|PILER-CR matches to MK494089 (Mycobacterium phage Ibrahim, complete genome) position: , mismatch: 8, identity: 0.771

gcctcctgatggatctccacgacgttgctggccct	CRISPR spacer
gattcctggtggatctccaccacgttgctgacggc	Protospacer
* .*****.*********** *********.*  .

62. spacer 4.23|1511652|35|NC_012814|PILER-CR matches to NC_024135 (Mycobacterium phage Bernal13, complete genome) position: , mismatch: 8, identity: 0.771

gcctcctgatggatctccacgacgttgctggccct	CRISPR spacer
gattcctggtggatctccaccacgttgctgacggc	Protospacer
* .*****.*********** *********.*  .

63. spacer 4.23|1511652|35|NC_012814|PILER-CR matches to MG925349 (Mycobacterium phage Mendokysei, complete genome) position: , mismatch: 8, identity: 0.771

gcctcctgatggatctccacgacgttgctggccct	CRISPR spacer
gattcctggtggatctccaccacgttgctgacggc	Protospacer
* .*****.*********** *********.*  .

64. spacer 4.23|1511652|35|NC_012814|PILER-CR matches to KM591905 (Mycobacterium phage RonRayGun, complete genome) position: , mismatch: 8, identity: 0.771

gcctcctgatggatctccacgacgttgctggccct	CRISPR spacer
gattcctggtggatctccaccacgttgctgacggc	Protospacer
* .*****.*********** *********.*  .

65. spacer 4.23|1511652|35|NC_012814|PILER-CR matches to MN735432 (Mycobacteriophage Whitty, complete genome) position: , mismatch: 8, identity: 0.771

gcctcctgatggatctccacgacgttgctggccct	CRISPR spacer
gattcctggtggatctccaccacgttgctgacggc	Protospacer
* .*****.*********** *********.*  .

66. spacer 4.38|1512732|34|NC_012814|PILER-CR matches to NZ_CP045383 (Labrenzia sp. THAF35 plasmid pTHAF35_c, complete sequence) position: , mismatch: 8, identity: 0.765

tcgcaggtgaatatcggtggcggcggcttgtcgt	CRISPR spacer
tcacaggtgaatatcggtggaggcagatggcgga	Protospacer
**.***************** ***.* * *. *

67. spacer 5.1|1911875|33|NC_012814|CRISPRCasFinder matches to MT939492 (Xanthomonas phage Xoo-sp14, complete genome) position: , mismatch: 8, identity: 0.758

cgtccgagagtggattcgcggattgtcttgatc	CRISPR spacer
tcccagagcggggattcgcggattgtcttggcc	Protospacer
. .* *** * *******************..*

Prophage detection

Region

Region Position

Protein_number

Hit_taxonomy

Key_proteins

Att_site

Prophage annotation

DBSCAN-SWA_1

419578 : 428179

Pandoravirus(33.33%)

The bacterium proteins that are colored denote the protein is present at specific phage-related keywords (such as 'capsid', 'head', 'integrase', 'plate', 'tail', 'fiber', 'coat', 'transposase', 'portal', 'terminase', 'protease' or 'lysin' and 'tRNA')

Protein_ID	Protein_Def	Hit_ID	Hit_Def	E-value	Identity
WP_004268491.1\|419578_420709_+	3-deoxy-7-phosphoheptulonate synthase	S4W5F1	Pandoravirus	1.3e-78	44.5
WP_004268492.1\|420923_422927_+	acetyltransferase	A0A193GZ69	Enterobacter_phage	2.3e-22	33.0
WP_004268493.1\|422999_424247_+	3-deoxy-7-phosphoheptulonate synthase	S4W5F1	Pandoravirus	4.6e-85	49.2
WP_004268494.1\|424325_425018_+	5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase	NA	NA	NA	NA
WP_004268496.1\|425049_426273_+	two-component sensor histidine kinase	W8CYF6	Bacillus_phage	2.8e-26	29.3
WP_004268504.1\|426269_426977_+	response regulator transcription factor	W8CYM9	Bacillus_phage	2.4e-35	33.5
WP_004268505.1\|427063_428179_+	phosphate ABC transporter substrate-binding protein PstS	E3SII0	Synechococcus_phage	4.6e-20	29.7

Anti-CRISPR protein detection

Acr ID	Acr position	Acr size	Homology with known anti	Neighbor HTH/AcRanker	Neighbor Aca	In prophage	Protospacer in prophage

Overview of predicted results

Overview of the results

Cas Category Instructions

Results visualization

1. NC_012814

Click the left colored region to show detailed information

CRISPR-Cas detection and classification

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Click the colored protein region to show detailed information

Self-targeting detection

MGE targeting detection<

Prophage detection

Anti-CRISPR protein detection